data_9MK7
# 
_entry.id   9MK7 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9MK7         pdb_00009mk7 10.2210/pdb9mk7/pdb 
WWPDB D_1000291143 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-02-26 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9MK7 
_pdbx_database_status.recvd_initial_deposition_date   2024-12-16 
_pdbx_database_status.SG_entry                        Y 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_contact_author.id                 1 
_pdbx_contact_author.email              l.halabelian@utoronto.ca 
_pdbx_contact_author.name_first         Levon 
_pdbx_contact_author.name_last          Halabelian 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-4361-3619 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Zeng, H.'                             1 ? 
'Ahmad, H.'                            2 ? 
'Dong, A.'                             3 ? 
'Seitova, A.'                          4 ? 
'Owen, D.'                             5 ? 
'Arrowsmith, C.H.'                     6 ? 
'Edwards, A.M.'                        7 ? 
'Halabelian, L.'                       8 ? 
'Structural Genomics Consortium (SGC)' 9 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To be published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Crystal structure of the WDR domain of WDR91 in complex with DR3634' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Zeng, H.'                             1 ? 
primary 'Ahmad, H.'                            2 ? 
primary 'Dong, A.'                             3 ? 
primary 'Seitova, A.'                          4 ? 
primary 'Owen, D.'                             5 ? 
primary 'Arrowsmith, C.H.'                     6 ? 
primary 'Edwards, A.M.'                        7 ? 
primary 'Halabelian, L.'                       8 ? 
primary 'Structural Genomics Consortium (SGC)' 9 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'WD repeat-containing protein 91' 41064.477 1  ? ? 'UNP residues 392-747' ? 
2 non-polymer syn 
'(1R)-1-({(6M)-2-(methylamino)-6-[3-(pyrrolidin-1-yl)phenyl]pyrimidin-4-yl}amino)-2,3-dihydro-1H-indene-4-carbonitrile' 410.514   
1  ? ? ?                      ? 
3 non-polymer syn 'UNKNOWN ATOM OR ION' ?         1  ? ? ?                      ? 
4 water       nat water 18.015    76 ? ? ?                      ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        WDR91 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MHHHHHHSSGRENLYFQGPEQPFIVLGQEEYGEHHSSIMHCRVDCSGRRVASLDVDGVIKVWSFNPIMQTKASSISKSPL
LSLEWATKRDRLLLLGSGVGTVRLYDTEAKKNLCEININDNMPRILSLACSPNGASFVCSAAAPSLTSQVDFSAPDIGSK
GMNQVPGRLLLWDTKTMKQQLQFSLDPEPIAINCTAFNHNGNLLVTGAADGVIRLFDMQQHECAMSWRAHYGEVYSVEFS
YDENTVYSIGEDGKFIQWNIHKSGLKVSEYSLPSDATGPFVLSGYSGYKQVQVPRGRLFAFDSEGNYMLTCSATGGVIYK
LGGDEKVLESCLSLGGHRAPVVTVDWSTAMDCGTCLTASMDGKIKLTTLLAHKA
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MHHHHHHSSGRENLYFQGPEQPFIVLGQEEYGEHHSSIMHCRVDCSGRRVASLDVDGVIKVWSFNPIMQTKASSISKSPL
LSLEWATKRDRLLLLGSGVGTVRLYDTEAKKNLCEININDNMPRILSLACSPNGASFVCSAAAPSLTSQVDFSAPDIGSK
GMNQVPGRLLLWDTKTMKQQLQFSLDPEPIAINCTAFNHNGNLLVTGAADGVIRLFDMQQHECAMSWRAHYGEVYSVEFS
YDENTVYSIGEDGKFIQWNIHKSGLKVSEYSLPSDATGPFVLSGYSGYKQVQVPRGRLFAFDSEGNYMLTCSATGGVIYK
LGGDEKVLESCLSLGGHRAPVVTVDWSTAMDCGTCLTASMDGKIKLTTLLAHKA
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 '(1R)-1-({(6M)-2-(methylamino)-6-[3-(pyrrolidin-1-yl)phenyl]pyrimidin-4-yl}amino)-2,3-dihydro-1H-indene-4-carbonitrile' A1BLV 
3 'UNKNOWN ATOM OR ION'                                                                                                   UNX   
4 water                                                                                                                   HOH   
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   HIS n 
1 3   HIS n 
1 4   HIS n 
1 5   HIS n 
1 6   HIS n 
1 7   HIS n 
1 8   SER n 
1 9   SER n 
1 10  GLY n 
1 11  ARG n 
1 12  GLU n 
1 13  ASN n 
1 14  LEU n 
1 15  TYR n 
1 16  PHE n 
1 17  GLN n 
1 18  GLY n 
1 19  PRO n 
1 20  GLU n 
1 21  GLN n 
1 22  PRO n 
1 23  PHE n 
1 24  ILE n 
1 25  VAL n 
1 26  LEU n 
1 27  GLY n 
1 28  GLN n 
1 29  GLU n 
1 30  GLU n 
1 31  TYR n 
1 32  GLY n 
1 33  GLU n 
1 34  HIS n 
1 35  HIS n 
1 36  SER n 
1 37  SER n 
1 38  ILE n 
1 39  MET n 
1 40  HIS n 
1 41  CYS n 
1 42  ARG n 
1 43  VAL n 
1 44  ASP n 
1 45  CYS n 
1 46  SER n 
1 47  GLY n 
1 48  ARG n 
1 49  ARG n 
1 50  VAL n 
1 51  ALA n 
1 52  SER n 
1 53  LEU n 
1 54  ASP n 
1 55  VAL n 
1 56  ASP n 
1 57  GLY n 
1 58  VAL n 
1 59  ILE n 
1 60  LYS n 
1 61  VAL n 
1 62  TRP n 
1 63  SER n 
1 64  PHE n 
1 65  ASN n 
1 66  PRO n 
1 67  ILE n 
1 68  MET n 
1 69  GLN n 
1 70  THR n 
1 71  LYS n 
1 72  ALA n 
1 73  SER n 
1 74  SER n 
1 75  ILE n 
1 76  SER n 
1 77  LYS n 
1 78  SER n 
1 79  PRO n 
1 80  LEU n 
1 81  LEU n 
1 82  SER n 
1 83  LEU n 
1 84  GLU n 
1 85  TRP n 
1 86  ALA n 
1 87  THR n 
1 88  LYS n 
1 89  ARG n 
1 90  ASP n 
1 91  ARG n 
1 92  LEU n 
1 93  LEU n 
1 94  LEU n 
1 95  LEU n 
1 96  GLY n 
1 97  SER n 
1 98  GLY n 
1 99  VAL n 
1 100 GLY n 
1 101 THR n 
1 102 VAL n 
1 103 ARG n 
1 104 LEU n 
1 105 TYR n 
1 106 ASP n 
1 107 THR n 
1 108 GLU n 
1 109 ALA n 
1 110 LYS n 
1 111 LYS n 
1 112 ASN n 
1 113 LEU n 
1 114 CYS n 
1 115 GLU n 
1 116 ILE n 
1 117 ASN n 
1 118 ILE n 
1 119 ASN n 
1 120 ASP n 
1 121 ASN n 
1 122 MET n 
1 123 PRO n 
1 124 ARG n 
1 125 ILE n 
1 126 LEU n 
1 127 SER n 
1 128 LEU n 
1 129 ALA n 
1 130 CYS n 
1 131 SER n 
1 132 PRO n 
1 133 ASN n 
1 134 GLY n 
1 135 ALA n 
1 136 SER n 
1 137 PHE n 
1 138 VAL n 
1 139 CYS n 
1 140 SER n 
1 141 ALA n 
1 142 ALA n 
1 143 ALA n 
1 144 PRO n 
1 145 SER n 
1 146 LEU n 
1 147 THR n 
1 148 SER n 
1 149 GLN n 
1 150 VAL n 
1 151 ASP n 
1 152 PHE n 
1 153 SER n 
1 154 ALA n 
1 155 PRO n 
1 156 ASP n 
1 157 ILE n 
1 158 GLY n 
1 159 SER n 
1 160 LYS n 
1 161 GLY n 
1 162 MET n 
1 163 ASN n 
1 164 GLN n 
1 165 VAL n 
1 166 PRO n 
1 167 GLY n 
1 168 ARG n 
1 169 LEU n 
1 170 LEU n 
1 171 LEU n 
1 172 TRP n 
1 173 ASP n 
1 174 THR n 
1 175 LYS n 
1 176 THR n 
1 177 MET n 
1 178 LYS n 
1 179 GLN n 
1 180 GLN n 
1 181 LEU n 
1 182 GLN n 
1 183 PHE n 
1 184 SER n 
1 185 LEU n 
1 186 ASP n 
1 187 PRO n 
1 188 GLU n 
1 189 PRO n 
1 190 ILE n 
1 191 ALA n 
1 192 ILE n 
1 193 ASN n 
1 194 CYS n 
1 195 THR n 
1 196 ALA n 
1 197 PHE n 
1 198 ASN n 
1 199 HIS n 
1 200 ASN n 
1 201 GLY n 
1 202 ASN n 
1 203 LEU n 
1 204 LEU n 
1 205 VAL n 
1 206 THR n 
1 207 GLY n 
1 208 ALA n 
1 209 ALA n 
1 210 ASP n 
1 211 GLY n 
1 212 VAL n 
1 213 ILE n 
1 214 ARG n 
1 215 LEU n 
1 216 PHE n 
1 217 ASP n 
1 218 MET n 
1 219 GLN n 
1 220 GLN n 
1 221 HIS n 
1 222 GLU n 
1 223 CYS n 
1 224 ALA n 
1 225 MET n 
1 226 SER n 
1 227 TRP n 
1 228 ARG n 
1 229 ALA n 
1 230 HIS n 
1 231 TYR n 
1 232 GLY n 
1 233 GLU n 
1 234 VAL n 
1 235 TYR n 
1 236 SER n 
1 237 VAL n 
1 238 GLU n 
1 239 PHE n 
1 240 SER n 
1 241 TYR n 
1 242 ASP n 
1 243 GLU n 
1 244 ASN n 
1 245 THR n 
1 246 VAL n 
1 247 TYR n 
1 248 SER n 
1 249 ILE n 
1 250 GLY n 
1 251 GLU n 
1 252 ASP n 
1 253 GLY n 
1 254 LYS n 
1 255 PHE n 
1 256 ILE n 
1 257 GLN n 
1 258 TRP n 
1 259 ASN n 
1 260 ILE n 
1 261 HIS n 
1 262 LYS n 
1 263 SER n 
1 264 GLY n 
1 265 LEU n 
1 266 LYS n 
1 267 VAL n 
1 268 SER n 
1 269 GLU n 
1 270 TYR n 
1 271 SER n 
1 272 LEU n 
1 273 PRO n 
1 274 SER n 
1 275 ASP n 
1 276 ALA n 
1 277 THR n 
1 278 GLY n 
1 279 PRO n 
1 280 PHE n 
1 281 VAL n 
1 282 LEU n 
1 283 SER n 
1 284 GLY n 
1 285 TYR n 
1 286 SER n 
1 287 GLY n 
1 288 TYR n 
1 289 LYS n 
1 290 GLN n 
1 291 VAL n 
1 292 GLN n 
1 293 VAL n 
1 294 PRO n 
1 295 ARG n 
1 296 GLY n 
1 297 ARG n 
1 298 LEU n 
1 299 PHE n 
1 300 ALA n 
1 301 PHE n 
1 302 ASP n 
1 303 SER n 
1 304 GLU n 
1 305 GLY n 
1 306 ASN n 
1 307 TYR n 
1 308 MET n 
1 309 LEU n 
1 310 THR n 
1 311 CYS n 
1 312 SER n 
1 313 ALA n 
1 314 THR n 
1 315 GLY n 
1 316 GLY n 
1 317 VAL n 
1 318 ILE n 
1 319 TYR n 
1 320 LYS n 
1 321 LEU n 
1 322 GLY n 
1 323 GLY n 
1 324 ASP n 
1 325 GLU n 
1 326 LYS n 
1 327 VAL n 
1 328 LEU n 
1 329 GLU n 
1 330 SER n 
1 331 CYS n 
1 332 LEU n 
1 333 SER n 
1 334 LEU n 
1 335 GLY n 
1 336 GLY n 
1 337 HIS n 
1 338 ARG n 
1 339 ALA n 
1 340 PRO n 
1 341 VAL n 
1 342 VAL n 
1 343 THR n 
1 344 VAL n 
1 345 ASP n 
1 346 TRP n 
1 347 SER n 
1 348 THR n 
1 349 ALA n 
1 350 MET n 
1 351 ASP n 
1 352 CYS n 
1 353 GLY n 
1 354 THR n 
1 355 CYS n 
1 356 LEU n 
1 357 THR n 
1 358 ALA n 
1 359 SER n 
1 360 MET n 
1 361 ASP n 
1 362 GLY n 
1 363 LYS n 
1 364 ILE n 
1 365 LYS n 
1 366 LEU n 
1 367 THR n 
1 368 THR n 
1 369 LEU n 
1 370 LEU n 
1 371 ALA n 
1 372 HIS n 
1 373 LYS n 
1 374 ALA n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   374 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'WDR91, HSPC049' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Spodoptera frugiperda' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     7108 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1BLV non-polymer         . 
'(1R)-1-({(6M)-2-(methylamino)-6-[3-(pyrrolidin-1-yl)phenyl]pyrimidin-4-yl}amino)-2,3-dihydro-1H-indene-4-carbonitrile' ? 
'C25 H26 N6'     410.514 
ALA   'L-peptide linking' y ALANINE ? 'C3 H7 N O2'     89.093  
ARG   'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 
ASN   'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3'    132.118 
ASP   'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS   'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S'   121.158 
GLN   'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3'   146.144 
GLU   'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY   'peptide linking'   y GLYCINE ? 'C2 H5 N O2'     75.067  
HIS   'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 
HOH   non-polymer         . WATER ? 'H2 O'           18.015  
ILE   'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2'    131.173 
LEU   'L-peptide linking' y LEUCINE ? 'C6 H13 N O2'    131.173 
LYS   'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 
MET   'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S'  149.211 
PHE   'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2'    165.189 
PRO   'L-peptide linking' y PROLINE ? 'C5 H9 N O2'     115.130 
SER   'L-peptide linking' y SERINE ? 'C3 H7 N O3'     105.093 
THR   'L-peptide linking' y THREONINE ? 'C4 H9 N O3'     119.119 
TRP   'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2'  204.225 
TYR   'L-peptide linking' y TYROSINE ? 'C9 H11 N O3'    181.189 
UNX   non-polymer         . 'UNKNOWN ATOM OR ION' ? ?                ?       
VAL   'L-peptide linking' y VALINE ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   374 ?   ?   ?   A . n 
A 1 2   HIS 2   375 ?   ?   ?   A . n 
A 1 3   HIS 3   376 ?   ?   ?   A . n 
A 1 4   HIS 4   377 ?   ?   ?   A . n 
A 1 5   HIS 5   378 ?   ?   ?   A . n 
A 1 6   HIS 6   379 ?   ?   ?   A . n 
A 1 7   HIS 7   380 ?   ?   ?   A . n 
A 1 8   SER 8   381 ?   ?   ?   A . n 
A 1 9   SER 9   382 ?   ?   ?   A . n 
A 1 10  GLY 10  383 ?   ?   ?   A . n 
A 1 11  ARG 11  384 ?   ?   ?   A . n 
A 1 12  GLU 12  385 ?   ?   ?   A . n 
A 1 13  ASN 13  386 ?   ?   ?   A . n 
A 1 14  LEU 14  387 ?   ?   ?   A . n 
A 1 15  TYR 15  388 ?   ?   ?   A . n 
A 1 16  PHE 16  389 ?   ?   ?   A . n 
A 1 17  GLN 17  390 ?   ?   ?   A . n 
A 1 18  GLY 18  391 ?   ?   ?   A . n 
A 1 19  PRO 19  392 ?   ?   ?   A . n 
A 1 20  GLU 20  393 ?   ?   ?   A . n 
A 1 21  GLN 21  394 394 GLN GLN A . n 
A 1 22  PRO 22  395 395 PRO PRO A . n 
A 1 23  PHE 23  396 396 PHE PHE A . n 
A 1 24  ILE 24  397 397 ILE ILE A . n 
A 1 25  VAL 25  398 398 VAL VAL A . n 
A 1 26  LEU 26  399 399 LEU LEU A . n 
A 1 27  GLY 27  400 400 GLY GLY A . n 
A 1 28  GLN 28  401 401 GLN GLN A . n 
A 1 29  GLU 29  402 402 GLU GLU A . n 
A 1 30  GLU 30  403 403 GLU GLU A . n 
A 1 31  TYR 31  404 404 TYR TYR A . n 
A 1 32  GLY 32  405 405 GLY GLY A . n 
A 1 33  GLU 33  406 406 GLU GLU A . n 
A 1 34  HIS 34  407 407 HIS HIS A . n 
A 1 35  HIS 35  408 408 HIS HIS A . n 
A 1 36  SER 36  409 409 SER SER A . n 
A 1 37  SER 37  410 410 SER SER A . n 
A 1 38  ILE 38  411 411 ILE ILE A . n 
A 1 39  MET 39  412 412 MET MET A . n 
A 1 40  HIS 40  413 413 HIS HIS A . n 
A 1 41  CYS 41  414 414 CYS CYS A . n 
A 1 42  ARG 42  415 415 ARG ARG A . n 
A 1 43  VAL 43  416 416 VAL VAL A . n 
A 1 44  ASP 44  417 417 ASP ASP A . n 
A 1 45  CYS 45  418 418 CYS CYS A . n 
A 1 46  SER 46  419 419 SER SER A . n 
A 1 47  GLY 47  420 420 GLY GLY A . n 
A 1 48  ARG 48  421 421 ARG ARG A . n 
A 1 49  ARG 49  422 422 ARG ARG A . n 
A 1 50  VAL 50  423 423 VAL VAL A . n 
A 1 51  ALA 51  424 424 ALA ALA A . n 
A 1 52  SER 52  425 425 SER SER A . n 
A 1 53  LEU 53  426 426 LEU LEU A . n 
A 1 54  ASP 54  427 427 ASP ASP A . n 
A 1 55  VAL 55  428 428 VAL VAL A . n 
A 1 56  ASP 56  429 429 ASP ASP A . n 
A 1 57  GLY 57  430 430 GLY GLY A . n 
A 1 58  VAL 58  431 431 VAL VAL A . n 
A 1 59  ILE 59  432 432 ILE ILE A . n 
A 1 60  LYS 60  433 433 LYS LYS A . n 
A 1 61  VAL 61  434 434 VAL VAL A . n 
A 1 62  TRP 62  435 435 TRP TRP A . n 
A 1 63  SER 63  436 436 SER SER A . n 
A 1 64  PHE 64  437 437 PHE PHE A . n 
A 1 65  ASN 65  438 438 ASN ASN A . n 
A 1 66  PRO 66  439 439 PRO PRO A . n 
A 1 67  ILE 67  440 440 ILE ILE A . n 
A 1 68  MET 68  441 441 MET MET A . n 
A 1 69  GLN 69  442 442 GLN GLN A . n 
A 1 70  THR 70  443 443 THR THR A . n 
A 1 71  LYS 71  444 444 LYS LYS A . n 
A 1 72  ALA 72  445 445 ALA ALA A . n 
A 1 73  SER 73  446 446 SER SER A . n 
A 1 74  SER 74  447 447 SER SER A . n 
A 1 75  ILE 75  448 448 ILE ILE A . n 
A 1 76  SER 76  449 449 SER SER A . n 
A 1 77  LYS 77  450 450 LYS LYS A . n 
A 1 78  SER 78  451 451 SER SER A . n 
A 1 79  PRO 79  452 452 PRO PRO A . n 
A 1 80  LEU 80  453 453 LEU LEU A . n 
A 1 81  LEU 81  454 454 LEU LEU A . n 
A 1 82  SER 82  455 455 SER SER A . n 
A 1 83  LEU 83  456 456 LEU LEU A . n 
A 1 84  GLU 84  457 457 GLU GLU A . n 
A 1 85  TRP 85  458 458 TRP TRP A . n 
A 1 86  ALA 86  459 459 ALA ALA A . n 
A 1 87  THR 87  460 460 THR THR A . n 
A 1 88  LYS 88  461 461 LYS LYS A . n 
A 1 89  ARG 89  462 462 ARG ARG A . n 
A 1 90  ASP 90  463 463 ASP ASP A . n 
A 1 91  ARG 91  464 464 ARG ARG A . n 
A 1 92  LEU 92  465 465 LEU LEU A . n 
A 1 93  LEU 93  466 466 LEU LEU A . n 
A 1 94  LEU 94  467 467 LEU LEU A . n 
A 1 95  LEU 95  468 468 LEU LEU A . n 
A 1 96  GLY 96  469 469 GLY GLY A . n 
A 1 97  SER 97  470 470 SER SER A . n 
A 1 98  GLY 98  471 471 GLY GLY A . n 
A 1 99  VAL 99  472 472 VAL VAL A . n 
A 1 100 GLY 100 473 473 GLY GLY A . n 
A 1 101 THR 101 474 474 THR THR A . n 
A 1 102 VAL 102 475 475 VAL VAL A . n 
A 1 103 ARG 103 476 476 ARG ARG A . n 
A 1 104 LEU 104 477 477 LEU LEU A . n 
A 1 105 TYR 105 478 478 TYR TYR A . n 
A 1 106 ASP 106 479 479 ASP ASP A . n 
A 1 107 THR 107 480 480 THR THR A . n 
A 1 108 GLU 108 481 481 GLU GLU A . n 
A 1 109 ALA 109 482 482 ALA ALA A . n 
A 1 110 LYS 110 483 483 LYS LYS A . n 
A 1 111 LYS 111 484 484 LYS LYS A . n 
A 1 112 ASN 112 485 485 ASN ASN A . n 
A 1 113 LEU 113 486 486 LEU LEU A . n 
A 1 114 CYS 114 487 487 CYS CYS A . n 
A 1 115 GLU 115 488 488 GLU GLU A . n 
A 1 116 ILE 116 489 489 ILE ILE A . n 
A 1 117 ASN 117 490 490 ASN ASN A . n 
A 1 118 ILE 118 491 491 ILE ILE A . n 
A 1 119 ASN 119 492 492 ASN ASN A . n 
A 1 120 ASP 120 493 493 ASP ASP A . n 
A 1 121 ASN 121 494 494 ASN ASN A . n 
A 1 122 MET 122 495 495 MET MET A . n 
A 1 123 PRO 123 496 496 PRO PRO A . n 
A 1 124 ARG 124 497 497 ARG ARG A . n 
A 1 125 ILE 125 498 498 ILE ILE A . n 
A 1 126 LEU 126 499 499 LEU LEU A . n 
A 1 127 SER 127 500 500 SER SER A . n 
A 1 128 LEU 128 501 501 LEU LEU A . n 
A 1 129 ALA 129 502 502 ALA ALA A . n 
A 1 130 CYS 130 503 503 CYS CYS A . n 
A 1 131 SER 131 504 504 SER SER A . n 
A 1 132 PRO 132 505 505 PRO PRO A . n 
A 1 133 ASN 133 506 506 ASN ASN A . n 
A 1 134 GLY 134 507 507 GLY GLY A . n 
A 1 135 ALA 135 508 508 ALA ALA A . n 
A 1 136 SER 136 509 509 SER SER A . n 
A 1 137 PHE 137 510 510 PHE PHE A . n 
A 1 138 VAL 138 511 511 VAL VAL A . n 
A 1 139 CYS 139 512 512 CYS CYS A . n 
A 1 140 SER 140 513 513 SER SER A . n 
A 1 141 ALA 141 514 514 ALA ALA A . n 
A 1 142 ALA 142 515 515 ALA ALA A . n 
A 1 143 ALA 143 516 516 ALA ALA A . n 
A 1 144 PRO 144 517 517 PRO PRO A . n 
A 1 145 SER 145 518 518 SER SER A . n 
A 1 146 LEU 146 519 519 LEU LEU A . n 
A 1 147 THR 147 520 ?   ?   ?   A . n 
A 1 148 SER 148 521 ?   ?   ?   A . n 
A 1 149 GLN 149 522 ?   ?   ?   A . n 
A 1 150 VAL 150 523 ?   ?   ?   A . n 
A 1 151 ASP 151 524 ?   ?   ?   A . n 
A 1 152 PHE 152 525 ?   ?   ?   A . n 
A 1 153 SER 153 526 ?   ?   ?   A . n 
A 1 154 ALA 154 527 ?   ?   ?   A . n 
A 1 155 PRO 155 528 ?   ?   ?   A . n 
A 1 156 ASP 156 529 ?   ?   ?   A . n 
A 1 157 ILE 157 530 ?   ?   ?   A . n 
A 1 158 GLY 158 531 ?   ?   ?   A . n 
A 1 159 SER 159 532 ?   ?   ?   A . n 
A 1 160 LYS 160 533 ?   ?   ?   A . n 
A 1 161 GLY 161 534 ?   ?   ?   A . n 
A 1 162 MET 162 535 535 MET MET A . n 
A 1 163 ASN 163 536 536 ASN ASN A . n 
A 1 164 GLN 164 537 537 GLN GLN A . n 
A 1 165 VAL 165 538 538 VAL VAL A . n 
A 1 166 PRO 166 539 539 PRO PRO A . n 
A 1 167 GLY 167 540 540 GLY GLY A . n 
A 1 168 ARG 168 541 541 ARG ARG A . n 
A 1 169 LEU 169 542 542 LEU LEU A . n 
A 1 170 LEU 170 543 543 LEU LEU A . n 
A 1 171 LEU 171 544 544 LEU LEU A . n 
A 1 172 TRP 172 545 545 TRP TRP A . n 
A 1 173 ASP 173 546 546 ASP ASP A . n 
A 1 174 THR 174 547 547 THR THR A . n 
A 1 175 LYS 175 548 548 LYS LYS A . n 
A 1 176 THR 176 549 549 THR THR A . n 
A 1 177 MET 177 550 550 MET MET A . n 
A 1 178 LYS 178 551 551 LYS LYS A . n 
A 1 179 GLN 179 552 552 GLN GLN A . n 
A 1 180 GLN 180 553 553 GLN GLN A . n 
A 1 181 LEU 181 554 554 LEU LEU A . n 
A 1 182 GLN 182 555 555 GLN GLN A . n 
A 1 183 PHE 183 556 556 PHE PHE A . n 
A 1 184 SER 184 557 557 SER SER A . n 
A 1 185 LEU 185 558 558 LEU LEU A . n 
A 1 186 ASP 186 559 559 ASP ASP A . n 
A 1 187 PRO 187 560 560 PRO PRO A . n 
A 1 188 GLU 188 561 561 GLU GLU A . n 
A 1 189 PRO 189 562 562 PRO PRO A . n 
A 1 190 ILE 190 563 563 ILE ILE A . n 
A 1 191 ALA 191 564 564 ALA ALA A . n 
A 1 192 ILE 192 565 565 ILE ILE A . n 
A 1 193 ASN 193 566 566 ASN ASN A . n 
A 1 194 CYS 194 567 567 CYS CYS A . n 
A 1 195 THR 195 568 568 THR THR A . n 
A 1 196 ALA 196 569 569 ALA ALA A . n 
A 1 197 PHE 197 570 570 PHE PHE A . n 
A 1 198 ASN 198 571 571 ASN ASN A . n 
A 1 199 HIS 199 572 572 HIS HIS A . n 
A 1 200 ASN 200 573 573 ASN ASN A . n 
A 1 201 GLY 201 574 574 GLY GLY A . n 
A 1 202 ASN 202 575 575 ASN ASN A . n 
A 1 203 LEU 203 576 576 LEU LEU A . n 
A 1 204 LEU 204 577 577 LEU LEU A . n 
A 1 205 VAL 205 578 578 VAL VAL A . n 
A 1 206 THR 206 579 579 THR THR A . n 
A 1 207 GLY 207 580 580 GLY GLY A . n 
A 1 208 ALA 208 581 581 ALA ALA A . n 
A 1 209 ALA 209 582 582 ALA ALA A . n 
A 1 210 ASP 210 583 583 ASP ASP A . n 
A 1 211 GLY 211 584 584 GLY GLY A . n 
A 1 212 VAL 212 585 585 VAL VAL A . n 
A 1 213 ILE 213 586 586 ILE ILE A . n 
A 1 214 ARG 214 587 587 ARG ARG A . n 
A 1 215 LEU 215 588 588 LEU LEU A . n 
A 1 216 PHE 216 589 589 PHE PHE A . n 
A 1 217 ASP 217 590 590 ASP ASP A . n 
A 1 218 MET 218 591 591 MET MET A . n 
A 1 219 GLN 219 592 592 GLN GLN A . n 
A 1 220 GLN 220 593 593 GLN GLN A . n 
A 1 221 HIS 221 594 594 HIS HIS A . n 
A 1 222 GLU 222 595 595 GLU GLU A . n 
A 1 223 CYS 223 596 596 CYS CYS A . n 
A 1 224 ALA 224 597 597 ALA ALA A . n 
A 1 225 MET 225 598 598 MET MET A . n 
A 1 226 SER 226 599 599 SER SER A . n 
A 1 227 TRP 227 600 600 TRP TRP A . n 
A 1 228 ARG 228 601 601 ARG ARG A . n 
A 1 229 ALA 229 602 602 ALA ALA A . n 
A 1 230 HIS 230 603 603 HIS HIS A . n 
A 1 231 TYR 231 604 604 TYR TYR A . n 
A 1 232 GLY 232 605 605 GLY GLY A . n 
A 1 233 GLU 233 606 606 GLU GLU A . n 
A 1 234 VAL 234 607 607 VAL VAL A . n 
A 1 235 TYR 235 608 608 TYR TYR A . n 
A 1 236 SER 236 609 609 SER SER A . n 
A 1 237 VAL 237 610 610 VAL VAL A . n 
A 1 238 GLU 238 611 611 GLU GLU A . n 
A 1 239 PHE 239 612 612 PHE PHE A . n 
A 1 240 SER 240 613 613 SER SER A . n 
A 1 241 TYR 241 614 614 TYR TYR A . n 
A 1 242 ASP 242 615 615 ASP ASP A . n 
A 1 243 GLU 243 616 616 GLU GLU A . n 
A 1 244 ASN 244 617 617 ASN ASN A . n 
A 1 245 THR 245 618 618 THR THR A . n 
A 1 246 VAL 246 619 619 VAL VAL A . n 
A 1 247 TYR 247 620 620 TYR TYR A . n 
A 1 248 SER 248 621 621 SER SER A . n 
A 1 249 ILE 249 622 622 ILE ILE A . n 
A 1 250 GLY 250 623 623 GLY GLY A . n 
A 1 251 GLU 251 624 624 GLU GLU A . n 
A 1 252 ASP 252 625 625 ASP ASP A . n 
A 1 253 GLY 253 626 626 GLY GLY A . n 
A 1 254 LYS 254 627 627 LYS LYS A . n 
A 1 255 PHE 255 628 628 PHE PHE A . n 
A 1 256 ILE 256 629 629 ILE ILE A . n 
A 1 257 GLN 257 630 630 GLN GLN A . n 
A 1 258 TRP 258 631 631 TRP TRP A . n 
A 1 259 ASN 259 632 632 ASN ASN A . n 
A 1 260 ILE 260 633 633 ILE ILE A . n 
A 1 261 HIS 261 634 634 HIS HIS A . n 
A 1 262 LYS 262 635 635 LYS LYS A . n 
A 1 263 SER 263 636 636 SER SER A . n 
A 1 264 GLY 264 637 637 GLY GLY A . n 
A 1 265 LEU 265 638 638 LEU LEU A . n 
A 1 266 LYS 266 639 639 LYS LYS A . n 
A 1 267 VAL 267 640 640 VAL VAL A . n 
A 1 268 SER 268 641 641 SER SER A . n 
A 1 269 GLU 269 642 642 GLU GLU A . n 
A 1 270 TYR 270 643 643 TYR TYR A . n 
A 1 271 SER 271 644 644 SER SER A . n 
A 1 272 LEU 272 645 645 LEU LEU A . n 
A 1 273 PRO 273 646 646 PRO PRO A . n 
A 1 274 SER 274 647 647 SER SER A . n 
A 1 275 ASP 275 648 648 ASP ASP A . n 
A 1 276 ALA 276 649 649 ALA ALA A . n 
A 1 277 THR 277 650 650 THR THR A . n 
A 1 278 GLY 278 651 651 GLY GLY A . n 
A 1 279 PRO 279 652 652 PRO PRO A . n 
A 1 280 PHE 280 653 653 PHE PHE A . n 
A 1 281 VAL 281 654 654 VAL VAL A . n 
A 1 282 LEU 282 655 655 LEU LEU A . n 
A 1 283 SER 283 656 656 SER SER A . n 
A 1 284 GLY 284 657 657 GLY GLY A . n 
A 1 285 TYR 285 658 658 TYR TYR A . n 
A 1 286 SER 286 659 659 SER SER A . n 
A 1 287 GLY 287 660 660 GLY GLY A . n 
A 1 288 TYR 288 661 661 TYR TYR A . n 
A 1 289 LYS 289 662 662 LYS LYS A . n 
A 1 290 GLN 290 663 663 GLN GLN A . n 
A 1 291 VAL 291 664 664 VAL VAL A . n 
A 1 292 GLN 292 665 665 GLN GLN A . n 
A 1 293 VAL 293 666 666 VAL VAL A . n 
A 1 294 PRO 294 667 667 PRO PRO A . n 
A 1 295 ARG 295 668 668 ARG ARG A . n 
A 1 296 GLY 296 669 669 GLY GLY A . n 
A 1 297 ARG 297 670 670 ARG ARG A . n 
A 1 298 LEU 298 671 671 LEU LEU A . n 
A 1 299 PHE 299 672 672 PHE PHE A . n 
A 1 300 ALA 300 673 673 ALA ALA A . n 
A 1 301 PHE 301 674 674 PHE PHE A . n 
A 1 302 ASP 302 675 675 ASP ASP A . n 
A 1 303 SER 303 676 676 SER SER A . n 
A 1 304 GLU 304 677 677 GLU GLU A . n 
A 1 305 GLY 305 678 678 GLY GLY A . n 
A 1 306 ASN 306 679 679 ASN ASN A . n 
A 1 307 TYR 307 680 680 TYR TYR A . n 
A 1 308 MET 308 681 681 MET MET A . n 
A 1 309 LEU 309 682 682 LEU LEU A . n 
A 1 310 THR 310 683 683 THR THR A . n 
A 1 311 CYS 311 684 684 CYS CYS A . n 
A 1 312 SER 312 685 685 SER SER A . n 
A 1 313 ALA 313 686 686 ALA ALA A . n 
A 1 314 THR 314 687 687 THR THR A . n 
A 1 315 GLY 315 688 688 GLY GLY A . n 
A 1 316 GLY 316 689 689 GLY GLY A . n 
A 1 317 VAL 317 690 690 VAL VAL A . n 
A 1 318 ILE 318 691 691 ILE ILE A . n 
A 1 319 TYR 319 692 692 TYR TYR A . n 
A 1 320 LYS 320 693 693 LYS LYS A . n 
A 1 321 LEU 321 694 694 LEU LEU A . n 
A 1 322 GLY 322 695 695 GLY GLY A . n 
A 1 323 GLY 323 696 696 GLY GLY A . n 
A 1 324 ASP 324 697 697 ASP ASP A . n 
A 1 325 GLU 325 698 698 GLU GLU A . n 
A 1 326 LYS 326 699 699 LYS LYS A . n 
A 1 327 VAL 327 700 700 VAL VAL A . n 
A 1 328 LEU 328 701 701 LEU LEU A . n 
A 1 329 GLU 329 702 702 GLU GLU A . n 
A 1 330 SER 330 703 703 SER SER A . n 
A 1 331 CYS 331 704 704 CYS CYS A . n 
A 1 332 LEU 332 705 705 LEU LEU A . n 
A 1 333 SER 333 706 706 SER SER A . n 
A 1 334 LEU 334 707 707 LEU LEU A . n 
A 1 335 GLY 335 708 708 GLY GLY A . n 
A 1 336 GLY 336 709 709 GLY GLY A . n 
A 1 337 HIS 337 710 710 HIS HIS A . n 
A 1 338 ARG 338 711 711 ARG ARG A . n 
A 1 339 ALA 339 712 712 ALA ALA A . n 
A 1 340 PRO 340 713 713 PRO PRO A . n 
A 1 341 VAL 341 714 714 VAL VAL A . n 
A 1 342 VAL 342 715 715 VAL VAL A . n 
A 1 343 THR 343 716 716 THR THR A . n 
A 1 344 VAL 344 717 717 VAL VAL A . n 
A 1 345 ASP 345 718 718 ASP ASP A . n 
A 1 346 TRP 346 719 719 TRP TRP A . n 
A 1 347 SER 347 720 720 SER SER A . n 
A 1 348 THR 348 721 721 THR THR A . n 
A 1 349 ALA 349 722 722 ALA ALA A . n 
A 1 350 MET 350 723 723 MET MET A . n 
A 1 351 ASP 351 724 724 ASP ASP A . n 
A 1 352 CYS 352 725 725 CYS CYS A . n 
A 1 353 GLY 353 726 726 GLY GLY A . n 
A 1 354 THR 354 727 727 THR THR A . n 
A 1 355 CYS 355 728 728 CYS CYS A . n 
A 1 356 LEU 356 729 729 LEU LEU A . n 
A 1 357 THR 357 730 730 THR THR A . n 
A 1 358 ALA 358 731 731 ALA ALA A . n 
A 1 359 SER 359 732 732 SER SER A . n 
A 1 360 MET 360 733 733 MET MET A . n 
A 1 361 ASP 361 734 734 ASP ASP A . n 
A 1 362 GLY 362 735 735 GLY GLY A . n 
A 1 363 LYS 363 736 736 LYS LYS A . n 
A 1 364 ILE 364 737 737 ILE ILE A . n 
A 1 365 LYS 365 738 738 LYS LYS A . n 
A 1 366 LEU 366 739 739 LEU LEU A . n 
A 1 367 THR 367 740 740 THR THR A . n 
A 1 368 THR 368 741 741 THR THR A . n 
A 1 369 LEU 369 742 742 LEU LEU A . n 
A 1 370 LEU 370 743 743 LEU LEU A . n 
A 1 371 ALA 371 744 744 ALA ALA A . n 
A 1 372 HIS 372 745 745 HIS HIS A . n 
A 1 373 LYS 373 746 ?   ?   ?   A . n 
A 1 374 ALA 374 747 ?   ?   ?   A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        A1BLV 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   A1BLV 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 A1BLV 1  801 801  A1BLV LIG A . 
C 3 UNX   1  802 1001 UNX   UNX A . 
D 4 HOH   1  901 117  HOH   HOH A . 
D 4 HOH   2  902 44   HOH   HOH A . 
D 4 HOH   3  903 32   HOH   HOH A . 
D 4 HOH   4  904 76   HOH   HOH A . 
D 4 HOH   5  905 105  HOH   HOH A . 
D 4 HOH   6  906 42   HOH   HOH A . 
D 4 HOH   7  907 88   HOH   HOH A . 
D 4 HOH   8  908 116  HOH   HOH A . 
D 4 HOH   9  909 82   HOH   HOH A . 
D 4 HOH   10 910 79   HOH   HOH A . 
D 4 HOH   11 911 71   HOH   HOH A . 
D 4 HOH   12 912 11   HOH   HOH A . 
D 4 HOH   13 913 100  HOH   HOH A . 
D 4 HOH   14 914 81   HOH   HOH A . 
D 4 HOH   15 915 109  HOH   HOH A . 
D 4 HOH   16 916 70   HOH   HOH A . 
D 4 HOH   17 917 43   HOH   HOH A . 
D 4 HOH   18 918 15   HOH   HOH A . 
D 4 HOH   19 919 85   HOH   HOH A . 
D 4 HOH   20 920 90   HOH   HOH A . 
D 4 HOH   21 921 56   HOH   HOH A . 
D 4 HOH   22 922 99   HOH   HOH A . 
D 4 HOH   23 923 50   HOH   HOH A . 
D 4 HOH   24 924 41   HOH   HOH A . 
D 4 HOH   25 925 113  HOH   HOH A . 
D 4 HOH   26 926 98   HOH   HOH A . 
D 4 HOH   27 927 61   HOH   HOH A . 
D 4 HOH   28 928 78   HOH   HOH A . 
D 4 HOH   29 929 72   HOH   HOH A . 
D 4 HOH   30 930 9    HOH   HOH A . 
D 4 HOH   31 931 3    HOH   HOH A . 
D 4 HOH   32 932 64   HOH   HOH A . 
D 4 HOH   33 933 111  HOH   HOH A . 
D 4 HOH   34 934 115  HOH   HOH A . 
D 4 HOH   35 935 75   HOH   HOH A . 
D 4 HOH   36 936 1    HOH   HOH A . 
D 4 HOH   37 937 21   HOH   HOH A . 
D 4 HOH   38 938 101  HOH   HOH A . 
D 4 HOH   39 939 73   HOH   HOH A . 
D 4 HOH   40 940 107  HOH   HOH A . 
D 4 HOH   41 941 51   HOH   HOH A . 
D 4 HOH   42 942 84   HOH   HOH A . 
D 4 HOH   43 943 106  HOH   HOH A . 
D 4 HOH   44 944 95   HOH   HOH A . 
D 4 HOH   45 945 26   HOH   HOH A . 
D 4 HOH   46 946 118  HOH   HOH A . 
D 4 HOH   47 947 86   HOH   HOH A . 
D 4 HOH   48 948 40   HOH   HOH A . 
D 4 HOH   49 949 69   HOH   HOH A . 
D 4 HOH   50 950 74   HOH   HOH A . 
D 4 HOH   51 951 65   HOH   HOH A . 
D 4 HOH   52 952 45   HOH   HOH A . 
D 4 HOH   53 953 97   HOH   HOH A . 
D 4 HOH   54 954 87   HOH   HOH A . 
D 4 HOH   55 955 5    HOH   HOH A . 
D 4 HOH   56 956 103  HOH   HOH A . 
D 4 HOH   57 957 60   HOH   HOH A . 
D 4 HOH   58 958 46   HOH   HOH A . 
D 4 HOH   59 959 39   HOH   HOH A . 
D 4 HOH   60 960 28   HOH   HOH A . 
D 4 HOH   61 961 96   HOH   HOH A . 
D 4 HOH   62 962 4    HOH   HOH A . 
D 4 HOH   63 963 112  HOH   HOH A . 
D 4 HOH   64 964 102  HOH   HOH A . 
D 4 HOH   65 965 47   HOH   HOH A . 
D 4 HOH   66 966 93   HOH   HOH A . 
D 4 HOH   67 967 108  HOH   HOH A . 
D 4 HOH   68 968 7    HOH   HOH A . 
D 4 HOH   69 969 80   HOH   HOH A . 
D 4 HOH   70 970 53   HOH   HOH A . 
D 4 HOH   71 971 92   HOH   HOH A . 
D 4 HOH   72 972 36   HOH   HOH A . 
D 4 HOH   73 973 13   HOH   HOH A . 
D 4 HOH   74 974 62   HOH   HOH A . 
D 4 HOH   75 975 33   HOH   HOH A . 
D 4 HOH   76 976 114  HOH   HOH A . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A GLN 394 ? CG  ? A GLN 21  CG  
2  1 Y 1 A GLN 394 ? CD  ? A GLN 21  CD  
3  1 Y 1 A GLN 394 ? OE1 ? A GLN 21  OE1 
4  1 Y 1 A GLN 394 ? NE2 ? A GLN 21  NE2 
5  1 Y 1 A ARG 421 ? NE  ? A ARG 48  NE  
6  1 Y 1 A ARG 421 ? CZ  ? A ARG 48  CZ  
7  1 Y 1 A ARG 421 ? NH1 ? A ARG 48  NH1 
8  1 Y 1 A ARG 421 ? NH2 ? A ARG 48  NH2 
9  1 Y 1 A ILE 432 ? CD1 ? A ILE 59  CD1 
10 1 Y 1 A ILE 448 ? CD1 ? A ILE 75  CD1 
11 1 Y 1 A LYS 450 ? CG  ? A LYS 77  CG  
12 1 Y 1 A LYS 450 ? CD  ? A LYS 77  CD  
13 1 Y 1 A LYS 450 ? CE  ? A LYS 77  CE  
14 1 Y 1 A LYS 450 ? NZ  ? A LYS 77  NZ  
15 1 Y 1 A LYS 483 ? NZ  ? A LYS 110 NZ  
16 1 Y 1 A LYS 484 ? CD  ? A LYS 111 CD  
17 1 Y 1 A LYS 484 ? CE  ? A LYS 111 CE  
18 1 Y 1 A LYS 484 ? NZ  ? A LYS 111 NZ  
19 1 Y 1 A MET 535 ? CG  ? A MET 162 CG  
20 1 Y 1 A MET 535 ? SD  ? A MET 162 SD  
21 1 Y 1 A MET 535 ? CE  ? A MET 162 CE  
22 1 Y 1 A ASN 536 ? CG  ? A ASN 163 CG  
23 1 Y 1 A ASN 536 ? OD1 ? A ASN 163 OD1 
24 1 Y 1 A ASN 536 ? ND2 ? A ASN 163 ND2 
25 1 Y 1 A LYS 548 ? CG  ? A LYS 175 CG  
26 1 Y 1 A LYS 548 ? CD  ? A LYS 175 CD  
27 1 Y 1 A LYS 548 ? CE  ? A LYS 175 CE  
28 1 Y 1 A LYS 548 ? NZ  ? A LYS 175 NZ  
29 1 Y 1 A LYS 551 ? NZ  ? A LYS 178 NZ  
30 1 Y 1 A TYR 658 ? CG  ? A TYR 285 CG  
31 1 Y 1 A TYR 658 ? CD1 ? A TYR 285 CD1 
32 1 Y 1 A TYR 658 ? CD2 ? A TYR 285 CD2 
33 1 Y 1 A TYR 658 ? CE1 ? A TYR 285 CE1 
34 1 Y 1 A TYR 658 ? CE2 ? A TYR 285 CE2 
35 1 Y 1 A TYR 658 ? CZ  ? A TYR 285 CZ  
36 1 Y 1 A TYR 658 ? OH  ? A TYR 285 OH  
37 1 Y 1 A SER 659 ? OG  ? A SER 286 OG  
38 1 Y 1 A LYS 693 ? CD  ? A LYS 320 CD  
39 1 Y 1 A LYS 693 ? CE  ? A LYS 320 CE  
40 1 Y 1 A LYS 693 ? NZ  ? A LYS 320 NZ  
41 1 Y 1 A ASP 697 ? CG  ? A ASP 324 CG  
42 1 Y 1 A ASP 697 ? OD1 ? A ASP 324 OD1 
43 1 Y 1 A ASP 697 ? OD2 ? A ASP 324 OD2 
44 1 Y 1 A GLU 698 ? CG  ? A GLU 325 CG  
45 1 Y 1 A GLU 698 ? CD  ? A GLU 325 CD  
46 1 Y 1 A GLU 698 ? OE1 ? A GLU 325 OE1 
47 1 Y 1 A GLU 698 ? OE2 ? A GLU 325 OE2 
48 1 Y 1 A LYS 699 ? CG  ? A LYS 326 CG  
49 1 Y 1 A LYS 699 ? CD  ? A LYS 326 CD  
50 1 Y 1 A LYS 699 ? CE  ? A LYS 326 CE  
51 1 Y 1 A LYS 699 ? NZ  ? A LYS 326 NZ  
52 1 Y 1 A VAL 700 ? CG1 ? A VAL 327 CG1 
53 1 Y 1 A VAL 700 ? CG2 ? A VAL 327 CG2 
54 1 Y 1 A GLU 702 ? CG  ? A GLU 329 CG  
55 1 Y 1 A GLU 702 ? CD  ? A GLU 329 CD  
56 1 Y 1 A GLU 702 ? OE1 ? A GLU 329 OE1 
57 1 Y 1 A GLU 702 ? OE2 ? A GLU 329 OE2 
58 1 Y 1 A ARG 711 ? CD  ? A ARG 338 CD  
59 1 Y 1 A ARG 711 ? NE  ? A ARG 338 NE  
60 1 Y 1 A ARG 711 ? CZ  ? A ARG 338 CZ  
61 1 Y 1 A ARG 711 ? NH1 ? A ARG 338 NH1 
62 1 Y 1 A ARG 711 ? NH2 ? A ARG 338 NH2 
63 1 Y 1 A ASP 724 ? CG  ? A ASP 351 CG  
64 1 Y 1 A ASP 724 ? OD1 ? A ASP 351 OD1 
65 1 Y 1 A ASP 724 ? OD2 ? A ASP 351 OD2 
66 1 Y 1 A LYS 736 ? CE  ? A LYS 363 CE  
67 1 Y 1 A LYS 736 ? NZ  ? A LYS 363 NZ  
68 1 Y 1 A HIS 745 ? CG  ? A HIS 372 CG  
69 1 Y 1 A HIS 745 ? ND1 ? A HIS 372 ND1 
70 1 Y 1 A HIS 745 ? CD2 ? A HIS 372 CD2 
71 1 Y 1 A HIS 745 ? CE1 ? A HIS 372 CE1 
72 1 Y 1 A HIS 745 ? NE2 ? A HIS 372 NE2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC   ? ? ? 5.8.0425 1 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? HKL-3000 ? ? ? .        2 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER   ? ? ? .        3 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? HKL-3000 ? ? ? .        4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9MK7 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     79.201 
_cell.length_a_esd                 ? 
_cell.length_b                     132.236 
_cell.length_b_esd                 ? 
_cell.length_c                     118.291 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9MK7 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                20 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'C 2 2 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9MK7 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.77 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          67.38 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '10% w/v PEG 8000, 20% v/v ethylene glycol, 0.02M of each alcohol,0.1M MES/imidazole pH6.5' 
_exptl_crystal_grow.pdbx_pH_range   6.5 
_exptl_crystal_grow.temp            291 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     CCD 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'RIGAKU SATURN A200' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2024-10-08 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1.54 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      'ROTATING ANODE' 
_diffrn_source.target                      ? 
_diffrn_source.type                        'RIGAKU FR-E+ SUPERBRIGHT' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.54 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   ? 
_diffrn_source.pdbx_synchrotron_site       ? 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9MK7 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.31 
_reflns.d_resolution_low                               50.00 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     27368 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.9 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                7.9 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          12.5 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               1.043 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.076 
_reflns.pdbx_Rpim_I_all                                0.027 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       215906 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.999 
_reflns.pdbx_CC_star                                   1.000 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.071 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
loop_
_reflns_shell.d_res_high 
_reflns_shell.d_res_low 
_reflns_shell.meanI_over_sigI_all 
_reflns_shell.meanI_over_sigI_obs 
_reflns_shell.number_measured_all 
_reflns_shell.number_measured_obs 
_reflns_shell.number_possible 
_reflns_shell.number_unique_all 
_reflns_shell.number_unique_obs 
_reflns_shell.percent_possible_obs 
_reflns_shell.Rmerge_F_all 
_reflns_shell.Rmerge_F_obs 
_reflns_shell.meanI_over_sigI_gt 
_reflns_shell.meanI_over_uI_all 
_reflns_shell.meanI_over_uI_gt 
_reflns_shell.number_measured_gt 
_reflns_shell.number_unique_gt 
_reflns_shell.percent_possible_gt 
_reflns_shell.Rmerge_F_gt 
_reflns_shell.Rmerge_I_gt 
_reflns_shell.pdbx_redundancy 
_reflns_shell.pdbx_chi_squared 
_reflns_shell.pdbx_netI_over_sigmaI_all 
_reflns_shell.pdbx_netI_over_sigmaI_obs 
_reflns_shell.pdbx_Rrim_I_all 
_reflns_shell.pdbx_Rpim_I_all 
_reflns_shell.pdbx_rejects 
_reflns_shell.pdbx_ordinal 
_reflns_shell.pdbx_diffrn_id 
_reflns_shell.pdbx_CC_half 
_reflns_shell.pdbx_CC_star 
_reflns_shell.pdbx_R_split 
_reflns_shell.percent_possible_all 
_reflns_shell.Rmerge_I_all 
_reflns_shell.Rmerge_I_obs 
_reflns_shell.pdbx_Rsym_value 
_reflns_shell.pdbx_percent_possible_ellipsoidal 
_reflns_shell.pdbx_percent_possible_spherical 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous 
_reflns_shell.pdbx_percent_possible_spherical_anomalous 
_reflns_shell.pdbx_redundancy_anomalous 
_reflns_shell.pdbx_CC_half_anomalous 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous 
_reflns_shell.pdbx_percent_possible_anomalous 
2.31 2.35  ? ? ? ? ? ? 1343 ? ? ? ? ? ? ? ? ? ? ? 7.0 1.010 ? ? 1.049 0.390 ? 1  1 0.694 0.905 ? 100.0 ? 0.971 ? ? ? ? ? ? ? ? ? 
2.35 2.39  ? ? ? ? ? ? 1360 ? ? ? ? ? ? ? ? ? ? ? 7.7 1.042 ? ? 1.011 0.360 ? 2  1 0.736 0.921 ? 99.9  ? 0.943 ? ? ? ? ? ? ? ? ? 
2.39 2.44  ? ? ? ? ? ? 1328 ? ? ? ? ? ? ? ? ? ? ? 7.9 1.081 ? ? 0.880 0.310 ? 3  1 0.827 0.951 ? 100.0 ? 0.823 ? ? ? ? ? ? ? ? ? 
2.44 2.49  ? ? ? ? ? ? 1365 ? ? ? ? ? ? ? ? ? ? ? 7.9 1.093 ? ? 0.817 0.287 ? 4  1 0.821 0.949 ? 100.0 ? 0.764 ? ? ? ? ? ? ? ? ? 
2.49 2.54  ? ? ? ? ? ? 1353 ? ? ? ? ? ? ? ? ? ? ? 8.0 1.118 ? ? 0.635 0.223 ? 5  1 0.880 0.968 ? 100.0 ? 0.593 ? ? ? ? ? ? ? ? ? 
2.54 2.60  ? ? ? ? ? ? 1339 ? ? ? ? ? ? ? ? ? ? ? 8.0 1.127 ? ? 0.550 0.193 ? 6  1 0.905 0.975 ? 100.0 ? 0.515 ? ? ? ? ? ? ? ? ? 
2.60 2.67  ? ? ? ? ? ? 1353 ? ? ? ? ? ? ? ? ? ? ? 8.0 1.099 ? ? 0.449 0.158 ? 7  1 0.941 0.985 ? 100.0 ? 0.420 ? ? ? ? ? ? ? ? ? 
2.67 2.74  ? ? ? ? ? ? 1365 ? ? ? ? ? ? ? ? ? ? ? 8.0 1.121 ? ? 0.361 0.126 ? 8  1 0.958 0.989 ? 100.0 ? 0.338 ? ? ? ? ? ? ? ? ? 
2.74 2.82  ? ? ? ? ? ? 1379 ? ? ? ? ? ? ? ? ? ? ? 8.0 1.126 ? ? 0.293 0.103 ? 9  1 0.969 0.992 ? 100.0 ? 0.274 ? ? ? ? ? ? ? ? ? 
2.82 2.91  ? ? ? ? ? ? 1324 ? ? ? ? ? ? ? ? ? ? ? 8.0 1.106 ? ? 0.235 0.082 ? 10 1 0.982 0.995 ? 100.0 ? 0.220 ? ? ? ? ? ? ? ? ? 
2.91 3.01  ? ? ? ? ? ? 1370 ? ? ? ? ? ? ? ? ? ? ? 8.0 1.146 ? ? 0.194 0.068 ? 11 1 0.988 0.997 ? 100.0 ? 0.182 ? ? ? ? ? ? ? ? ? 
3.01 3.13  ? ? ? ? ? ? 1362 ? ? ? ? ? ? ? ? ? ? ? 8.0 1.127 ? ? 0.140 0.049 ? 12 1 0.992 0.998 ? 100.0 ? 0.131 ? ? ? ? ? ? ? ? ? 
3.13 3.28  ? ? ? ? ? ? 1374 ? ? ? ? ? ? ? ? ? ? ? 8.0 0.987 ? ? 0.100 0.035 ? 13 1 0.996 0.999 ? 100.0 ? 0.093 ? ? ? ? ? ? ? ? ? 
3.28 3.45  ? ? ? ? ? ? 1362 ? ? ? ? ? ? ? ? ? ? ? 8.1 0.938 ? ? 0.073 0.025 ? 14 1 0.998 0.999 ? 100.0 ? 0.068 ? ? ? ? ? ? ? ? ? 
3.45 3.67  ? ? ? ? ? ? 1386 ? ? ? ? ? ? ? ? ? ? ? 8.0 1.037 ? ? 0.056 0.020 ? 15 1 0.998 1.000 ? 100.0 ? 0.052 ? ? ? ? ? ? ? ? ? 
3.67 3.95  ? ? ? ? ? ? 1363 ? ? ? ? ? ? ? ? ? ? ? 8.0 1.025 ? ? 0.050 0.018 ? 16 1 0.999 1.000 ? 100.0 ? 0.047 ? ? ? ? ? ? ? ? ? 
3.95 4.35  ? ? ? ? ? ? 1376 ? ? ? ? ? ? ? ? ? ? ? 8.0 0.671 ? ? 0.038 0.013 ? 17 1 0.999 1.000 ? 100.0 ? 0.036 ? ? ? ? ? ? ? ? ? 
4.35 4.98  ? ? ? ? ? ? 1399 ? ? ? ? ? ? ? ? ? ? ? 7.9 0.941 ? ? 0.030 0.011 ? 18 1 0.999 1.000 ? 100.0 ? 0.028 ? ? ? ? ? ? ? ? ? 
4.98 6.27  ? ? ? ? ? ? 1407 ? ? ? ? ? ? ? ? ? ? ? 7.9 1.145 ? ? 0.031 0.011 ? 19 1 1.000 1.000 ? 100.0 ? 0.029 ? ? ? ? ? ? ? ? ? 
6.27 50.00 ? ? ? ? ? ? 1460 ? ? ? ? ? ? ? ? ? ? ? 7.3 0.921 ? ? 0.025 0.009 ? 20 1 1.000 1.000 ? 98.1  ? 0.024 ? ? ? ? ? ? ? ? ? 
# 
_refine.aniso_B[1][1]                            -0.69 
_refine.aniso_B[1][2]                            -0.00 
_refine.aniso_B[1][3]                            0.00 
_refine.aniso_B[2][2]                            -0.57 
_refine.aniso_B[2][3]                            -0.00 
_refine.aniso_B[3][3]                            1.26 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               49.790 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.951 
_refine.correlation_coeff_Fo_to_Fc_free          0.926 
_refine.details                                  'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9MK7 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.31 
_refine.ls_d_res_low                             25.90 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     25931 
_refine.ls_number_reflns_R_free                  1376 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.45 
_refine.ls_percent_reflns_R_free                 5.0 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.20171 
_refine.ls_R_factor_R_free                       0.23777 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.19980 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    MASK 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'MAXIMUM LIKELIHOOD' 
_refine.pdbx_R_Free_selection_details            RANDOM 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.196 
_refine.pdbx_overall_ESU_R_Free                  0.179 
_refine.pdbx_solvent_vdw_probe_radii             1.20 
_refine.pdbx_solvent_ion_probe_radii             0.80 
_refine.pdbx_solvent_shrinkage_radii             0.80 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             11.398 
_refine.overall_SU_ML                            0.132 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         1 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.31 
_refine_hist.d_res_low                        25.90 
_refine_hist.number_atoms_solvent             76 
_refine_hist.number_atoms_total               2621 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        2544 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         1 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.010  0.012  2627 ? r_bond_refined_d             ? ? 
'X-RAY DIFFRACTION' ? 0.002  0.016  2390 ? r_bond_other_d               ? ? 
'X-RAY DIFFRACTION' ? 1.405  1.792  3578 ? r_angle_refined_deg          ? ? 
'X-RAY DIFFRACTION' ? 0.473  1.738  5498 ? r_angle_other_deg            ? ? 
'X-RAY DIFFRACTION' ? 8.406  5.000  341  ? r_dihedral_angle_1_deg       ? ? 
'X-RAY DIFFRACTION' ? 11.556 5.000  11   ? r_dihedral_angle_2_deg       ? ? 
'X-RAY DIFFRACTION' ? 14.715 10.000 393  ? r_dihedral_angle_3_deg       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_dihedral_angle_4_deg       ? ? 
'X-RAY DIFFRACTION' ? 0.067  0.200  404  ? r_chiral_restr               ? ? 
'X-RAY DIFFRACTION' ? 0.008  0.020  3188 ? r_gen_planes_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.020  586  ? r_gen_planes_other           ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_nbd_refined                ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_nbd_other                  ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_nbtor_refined              ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_nbtor_other                ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_xyhbond_nbd_refined        ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_xyhbond_nbd_other          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_metal_ion_refined          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_metal_ion_other            ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_symmetry_vdw_refined       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_symmetry_vdw_other         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_symmetry_hbond_refined     ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_symmetry_hbond_other       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_symmetry_metal_ion_refined ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_symmetry_metal_ion_other   ? ? 
'X-RAY DIFFRACTION' ? 2.840  2.822  1361 ? r_mcbond_it                  ? ? 
'X-RAY DIFFRACTION' ? 2.839  2.822  1361 ? r_mcbond_other               ? ? 
'X-RAY DIFFRACTION' ? 4.372  5.057  1703 ? r_mcangle_it                 ? ? 
'X-RAY DIFFRACTION' ? 4.371  5.059  1704 ? r_mcangle_other              ? ? 
'X-RAY DIFFRACTION' ? 3.515  3.069  1266 ? r_scbond_it                  ? ? 
'X-RAY DIFFRACTION' ? 3.513  3.071  1267 ? r_scbond_other               ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_scangle_it                 ? ? 
'X-RAY DIFFRACTION' ? 5.333  5.519  1876 ? r_scangle_other              ? ? 
'X-RAY DIFFRACTION' ? 7.655  25.89  2634 ? r_long_range_B_refined       ? ? 
'X-RAY DIFFRACTION' ? 7.657  25.85  2624 ? r_long_range_B_other         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_rigid_bond_restr           ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_sphericity_free            ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_sphericity_bonded          ? ? 
# 
_refine_ls_shell.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_ls_shell.d_res_high                       2.315 
_refine_ls_shell.d_res_low                        2.374 
_refine_ls_shell.number_reflns_all                ? 
_refine_ls_shell.number_reflns_obs                ? 
_refine_ls_shell.number_reflns_R_free             85 
_refine_ls_shell.number_reflns_R_work             1823 
_refine_ls_shell.percent_reflns_obs               95.98 
_refine_ls_shell.percent_reflns_R_free            ? 
_refine_ls_shell.R_factor_all                     ? 
_refine_ls_shell.R_factor_obs                     ? 
_refine_ls_shell.R_factor_R_free_error            ? 
_refine_ls_shell.R_factor_R_work                  0.317 
_refine_ls_shell.redundancy_reflns_all            ? 
_refine_ls_shell.redundancy_reflns_obs            ? 
_refine_ls_shell.wR_factor_all                    ? 
_refine_ls_shell.wR_factor_obs                    ? 
_refine_ls_shell.wR_factor_R_free                 ? 
_refine_ls_shell.wR_factor_R_work                 ? 
_refine_ls_shell.pdbx_R_complete                  ? 
_refine_ls_shell.pdbx_total_number_of_bins_used   20 
_refine_ls_shell.pdbx_phase_error                 ? 
_refine_ls_shell.pdbx_fsc_work                    ? 
_refine_ls_shell.pdbx_fsc_free                    ? 
_refine_ls_shell.R_factor_R_free                  0.312 
# 
_struct.entry_id                     9MK7 
_struct.title                        'Crystal structure of the WDR domain of WDR91 in complex with DR3634' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9MK7 
_struct_keywords.text            
'WD-repeat, WDR, WDR91, SGC, TRANSPORT PROTEIN, Structural Genomics, PSI-Biology, Structural Genomics Consortium' 
_struct_keywords.pdbx_keywords   'TRANSPORT PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    WDR91_HUMAN 
_struct_ref.pdbx_db_accession          A4D1P6 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;PEQPFIVLGQEEYGEHHSSIMHCRVDCSGRRVASLDVDGVIKVWSFNPIMQTKASSISKSPLLSLEWATKRDRLLLLGSG
VGTVRLYDTEAKKNLCEININDNMPRILSLACSPNGASFVCSAAAPSLTSQVDFSAPDIGSKGMNQVPGRLLLWDTKTMK
QQLQFSLDPEPIAINCTAFNHNGNLLVTGAADGVIRLFDMQQHECAMSWRAHYGEVYSVEFSYDENTVYSIGEDGKFIQW
NIHKSGLKVSEYSLPSDATGPFVLSGYSGYKQVQVPRGRLFAFDSEGNYMLTCSATGGVIYKLGGDEKVLESCLSLGGHR
APVVTVDWSTAMDCGTCLTASMDGKIKLTTLLAHKA
;
_struct_ref.pdbx_align_begin           392 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9MK7 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 19 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 374 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             A4D1P6 
_struct_ref_seq.db_align_beg                  392 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  747 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       392 
_struct_ref_seq.pdbx_auth_seq_align_end       747 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9MK7 MET A 1  ? UNP A4D1P6 ? ? 'expression tag' 374 1  
1 9MK7 HIS A 2  ? UNP A4D1P6 ? ? 'expression tag' 375 2  
1 9MK7 HIS A 3  ? UNP A4D1P6 ? ? 'expression tag' 376 3  
1 9MK7 HIS A 4  ? UNP A4D1P6 ? ? 'expression tag' 377 4  
1 9MK7 HIS A 5  ? UNP A4D1P6 ? ? 'expression tag' 378 5  
1 9MK7 HIS A 6  ? UNP A4D1P6 ? ? 'expression tag' 379 6  
1 9MK7 HIS A 7  ? UNP A4D1P6 ? ? 'expression tag' 380 7  
1 9MK7 SER A 8  ? UNP A4D1P6 ? ? 'expression tag' 381 8  
1 9MK7 SER A 9  ? UNP A4D1P6 ? ? 'expression tag' 382 9  
1 9MK7 GLY A 10 ? UNP A4D1P6 ? ? 'expression tag' 383 10 
1 9MK7 ARG A 11 ? UNP A4D1P6 ? ? 'expression tag' 384 11 
1 9MK7 GLU A 12 ? UNP A4D1P6 ? ? 'expression tag' 385 12 
1 9MK7 ASN A 13 ? UNP A4D1P6 ? ? 'expression tag' 386 13 
1 9MK7 LEU A 14 ? UNP A4D1P6 ? ? 'expression tag' 387 14 
1 9MK7 TYR A 15 ? UNP A4D1P6 ? ? 'expression tag' 388 15 
1 9MK7 PHE A 16 ? UNP A4D1P6 ? ? 'expression tag' 389 16 
1 9MK7 GLN A 17 ? UNP A4D1P6 ? ? 'expression tag' 390 17 
1 9MK7 GLY A 18 ? UNP A4D1P6 ? ? 'expression tag' 391 18 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
_struct_conf.conf_type_id            HELX_P 
_struct_conf.id                      HELX_P1 
_struct_conf.pdbx_PDB_helix_id       AA1 
_struct_conf.beg_label_comp_id       PRO 
_struct_conf.beg_label_asym_id       A 
_struct_conf.beg_label_seq_id        273 
_struct_conf.pdbx_beg_PDB_ins_code   ? 
_struct_conf.end_label_comp_id       THR 
_struct_conf.end_label_asym_id       A 
_struct_conf.end_label_seq_id        277 
_struct_conf.pdbx_end_PDB_ins_code   ? 
_struct_conf.beg_auth_comp_id        PRO 
_struct_conf.beg_auth_asym_id        A 
_struct_conf.beg_auth_seq_id         646 
_struct_conf.end_auth_comp_id        THR 
_struct_conf.end_auth_asym_id        A 
_struct_conf.end_auth_seq_id         650 
_struct_conf.pdbx_PDB_helix_class    5 
_struct_conf.details                 ? 
_struct_conf.pdbx_PDB_helix_length   5 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 ASN 65  A . ? ASN 438 A PRO 66  A ? PRO 439 A 1 8.93 
2 ASP 186 A . ? ASP 559 A PRO 187 A ? PRO 560 A 1 0.95 
3 GLY 278 A . ? GLY 651 A PRO 279 A ? PRO 652 A 1 4.80 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 4 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 4 ? 
AA7 ? 2 ? 
AA8 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE A 24  ? TYR A 31  ? ILE A 397 TYR A 404 
AA1 2 ILE A 364 ? LEU A 370 ? ILE A 737 LEU A 743 
AA1 3 CYS A 352 ? SER A 359 ? CYS A 725 SER A 732 
AA1 4 VAL A 341 ? ALA A 349 ? VAL A 714 ALA A 722 
AA2 1 ILE A 38  ? VAL A 43  ? ILE A 411 VAL A 416 
AA2 2 VAL A 50  ? ASP A 54  ? VAL A 423 ASP A 427 
AA2 3 VAL A 58  ? SER A 63  ? VAL A 431 SER A 436 
AA2 4 GLN A 69  ? ILE A 75  ? GLN A 442 ILE A 448 
AA3 1 LEU A 80  ? TRP A 85  ? LEU A 453 TRP A 458 
AA3 2 LEU A 92  ? SER A 97  ? LEU A 465 SER A 470 
AA3 3 THR A 101 ? ASP A 106 ? THR A 474 ASP A 479 
AA3 4 LYS A 111 ? ASN A 117 ? LYS A 484 ASN A 490 
AA4 1 ARG A 124 ? CYS A 130 ? ARG A 497 CYS A 503 
AA4 2 SER A 136 ? ALA A 142 ? SER A 509 ALA A 515 
AA4 3 GLY A 167 ? ASP A 173 ? GLY A 540 ASP A 546 
AA4 4 LYS A 178 ? PHE A 183 ? LYS A 551 PHE A 556 
AA5 1 ILE A 192 ? PHE A 197 ? ILE A 565 PHE A 570 
AA5 2 LEU A 203 ? ALA A 208 ? LEU A 576 ALA A 581 
AA5 3 VAL A 212 ? ASP A 217 ? VAL A 585 ASP A 590 
AA5 4 GLU A 222 ? ARG A 228 ? GLU A 595 ARG A 601 
AA6 1 VAL A 234 ? PHE A 239 ? VAL A 607 PHE A 612 
AA6 2 THR A 245 ? GLY A 250 ? THR A 618 GLY A 623 
AA6 3 LYS A 254 ? ASN A 259 ? LYS A 627 ASN A 632 
AA6 4 LYS A 266 ? SER A 271 ? LYS A 639 SER A 644 
AA7 1 PHE A 280 ? SER A 283 ? PHE A 653 SER A 656 
AA7 2 LYS A 289 ? GLN A 292 ? LYS A 662 GLN A 665 
AA8 1 PHE A 299 ? PHE A 301 ? PHE A 672 PHE A 674 
AA8 2 TYR A 307 ? THR A 310 ? TYR A 680 THR A 683 
AA8 3 VAL A 317 ? LYS A 320 ? VAL A 690 LYS A 693 
AA8 4 SER A 330 ? SER A 333 ? SER A 703 SER A 706 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N TYR A 31  ? N TYR A 404 O ILE A 364 ? O ILE A 737 
AA1 2 3 O LEU A 369 ? O LEU A 742 N GLY A 353 ? N GLY A 726 
AA1 3 4 O THR A 354 ? O THR A 727 N SER A 347 ? N SER A 720 
AA2 1 2 N MET A 39  ? N MET A 412 O LEU A 53  ? O LEU A 426 
AA2 2 3 N VAL A 50  ? N VAL A 423 O TRP A 62  ? O TRP A 435 
AA2 3 4 N VAL A 61  ? N VAL A 434 O LYS A 71  ? O LYS A 444 
AA3 1 2 N GLU A 84  ? N GLU A 457 O LEU A 94  ? O LEU A 467 
AA3 2 3 N LEU A 93  ? N LEU A 466 O TYR A 105 ? O TYR A 478 
AA3 3 4 N LEU A 104 ? N LEU A 477 O LEU A 113 ? O LEU A 486 
AA4 1 2 N ALA A 129 ? N ALA A 502 O VAL A 138 ? O VAL A 511 
AA4 2 3 N CYS A 139 ? N CYS A 512 O LEU A 170 ? O LEU A 543 
AA4 3 4 N LEU A 171 ? N LEU A 544 O GLN A 180 ? O GLN A 553 
AA5 1 2 N ALA A 196 ? N ALA A 569 O VAL A 205 ? O VAL A 578 
AA5 2 3 N LEU A 204 ? N LEU A 577 O PHE A 216 ? O PHE A 589 
AA5 3 4 N LEU A 215 ? N LEU A 588 O MET A 225 ? O MET A 598 
AA6 1 2 N GLU A 238 ? N GLU A 611 O TYR A 247 ? O TYR A 620 
AA6 2 3 N VAL A 246 ? N VAL A 619 O TRP A 258 ? O TRP A 631 
AA6 3 4 N GLN A 257 ? N GLN A 630 O VAL A 267 ? O VAL A 640 
AA7 1 2 N PHE A 280 ? N PHE A 653 O GLN A 292 ? O GLN A 665 
AA8 1 2 N ALA A 300 ? N ALA A 673 O LEU A 309 ? O LEU A 682 
AA8 2 3 N MET A 308 ? N MET A 681 O TYR A 319 ? O TYR A 692 
AA8 3 4 N ILE A 318 ? N ILE A 691 O LEU A 332 ? O LEU A 705 
# 
_pdbx_entry_details.entry_id                   9MK7 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   ND2 
_pdbx_validate_close_contact.auth_asym_id_1   A 
_pdbx_validate_close_contact.auth_comp_id_1   ASN 
_pdbx_validate_close_contact.auth_seq_id_1    573 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   OD1 
_pdbx_validate_close_contact.auth_asym_id_2   A 
_pdbx_validate_close_contact.auth_comp_id_2   ASN 
_pdbx_validate_close_contact.auth_seq_id_2    575 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             2.02 
# 
_pdbx_validate_rmsd_bond.id                        1 
_pdbx_validate_rmsd_bond.PDB_model_num             1 
_pdbx_validate_rmsd_bond.auth_atom_id_1            CD 
_pdbx_validate_rmsd_bond.auth_asym_id_1            A 
_pdbx_validate_rmsd_bond.auth_comp_id_1            GLU 
_pdbx_validate_rmsd_bond.auth_seq_id_1             611 
_pdbx_validate_rmsd_bond.PDB_ins_code_1            ? 
_pdbx_validate_rmsd_bond.label_alt_id_1            ? 
_pdbx_validate_rmsd_bond.auth_atom_id_2            OE2 
_pdbx_validate_rmsd_bond.auth_asym_id_2            A 
_pdbx_validate_rmsd_bond.auth_comp_id_2            GLU 
_pdbx_validate_rmsd_bond.auth_seq_id_2             611 
_pdbx_validate_rmsd_bond.PDB_ins_code_2            ? 
_pdbx_validate_rmsd_bond.label_alt_id_2            ? 
_pdbx_validate_rmsd_bond.bond_value                1.318 
_pdbx_validate_rmsd_bond.bond_target_value         1.252 
_pdbx_validate_rmsd_bond.bond_deviation            0.066 
_pdbx_validate_rmsd_bond.bond_standard_deviation   0.011 
_pdbx_validate_rmsd_bond.linker_flag               N 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 N  A LEU 456 ? ? CA A LEU 456 ? ? CB  A LEU 456 ? ? 98.03 110.40 -12.37 2.00 N 
2 1 CA A THR 687 ? ? CB A THR 687 ? ? OG1 A THR 687 ? ? 96.40 109.00 -12.60 2.10 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 PHE A 437 ? ? -145.98 -9.78  
2 1 ASN A 492 ? ? -67.30  79.11  
3 1 MET A 598 ? ? -173.42 138.19 
4 1 LYS A 635 ? ? -166.05 97.32  
5 1 ARG A 668 ? ? -142.02 -46.47 
# 
_pdbx_validate_peptide_omega.id               1 
_pdbx_validate_peptide_omega.PDB_model_num    1 
_pdbx_validate_peptide_omega.auth_comp_id_1   TYR 
_pdbx_validate_peptide_omega.auth_asym_id_1   A 
_pdbx_validate_peptide_omega.auth_seq_id_1    658 
_pdbx_validate_peptide_omega.PDB_ins_code_1   ? 
_pdbx_validate_peptide_omega.label_alt_id_1   ? 
_pdbx_validate_peptide_omega.auth_comp_id_2   SER 
_pdbx_validate_peptide_omega.auth_asym_id_2   A 
_pdbx_validate_peptide_omega.auth_seq_id_2    659 
_pdbx_validate_peptide_omega.PDB_ins_code_2   ? 
_pdbx_validate_peptide_omega.label_alt_id_2   ? 
_pdbx_validate_peptide_omega.omega            -147.57 
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1 1 ARG A 464 ? ? 0.095 'SIDE CHAIN' 
2 1 ARG A 668 ? ? 0.090 'SIDE CHAIN' 
3 1 ARG A 670 ? ? 0.136 'SIDE CHAIN' 
# 
_pdbx_SG_project.id                    1 
_pdbx_SG_project.project_name          PSI:Biology 
_pdbx_SG_project.full_name_of_center   'Structural Genomics Consortium' 
_pdbx_SG_project.initial_of_center     SGC 
# 
_pdbx_refine_tls.id               1 
_pdbx_refine_tls.pdbx_refine_id   'X-RAY DIFFRACTION' 
_pdbx_refine_tls.details          ? 
_pdbx_refine_tls.method           refined 
_pdbx_refine_tls.origin_x         -31.3823 
_pdbx_refine_tls.origin_y         -21.1446 
_pdbx_refine_tls.origin_z         -7.8060 
_pdbx_refine_tls.T[1][1]          0.1938 
_pdbx_refine_tls.T[1][1]_esd      ? 
_pdbx_refine_tls.T[1][2]          0.0045 
_pdbx_refine_tls.T[1][2]_esd      ? 
_pdbx_refine_tls.T[1][3]          -0.0079 
_pdbx_refine_tls.T[1][3]_esd      ? 
_pdbx_refine_tls.T[2][2]          0.0138 
_pdbx_refine_tls.T[2][2]_esd      ? 
_pdbx_refine_tls.T[2][3]          0.0336 
_pdbx_refine_tls.T[2][3]_esd      ? 
_pdbx_refine_tls.T[3][3]          0.0903 
_pdbx_refine_tls.T[3][3]_esd      ? 
_pdbx_refine_tls.L[1][1]          3.6883 
_pdbx_refine_tls.L[1][1]_esd      ? 
_pdbx_refine_tls.L[1][2]          0.1505 
_pdbx_refine_tls.L[1][2]_esd      ? 
_pdbx_refine_tls.L[1][3]          0.7661 
_pdbx_refine_tls.L[1][3]_esd      ? 
_pdbx_refine_tls.L[2][2]          1.9603 
_pdbx_refine_tls.L[2][2]_esd      ? 
_pdbx_refine_tls.L[2][3]          0.6390 
_pdbx_refine_tls.L[2][3]_esd      ? 
_pdbx_refine_tls.L[3][3]          3.3379 
_pdbx_refine_tls.L[3][3]_esd      ? 
_pdbx_refine_tls.S[1][1]          -0.0496 
_pdbx_refine_tls.S[1][1]_esd      ? 
_pdbx_refine_tls.S[1][2]          0.0958 
_pdbx_refine_tls.S[1][2]_esd      ? 
_pdbx_refine_tls.S[1][3]          0.1024 
_pdbx_refine_tls.S[1][3]_esd      ? 
_pdbx_refine_tls.S[2][1]          0.2489 
_pdbx_refine_tls.S[2][1]_esd      ? 
_pdbx_refine_tls.S[2][2]          -0.0740 
_pdbx_refine_tls.S[2][2]_esd      ? 
_pdbx_refine_tls.S[2][3]          -0.2383 
_pdbx_refine_tls.S[2][3]_esd      ? 
_pdbx_refine_tls.S[3][1]          0.0207 
_pdbx_refine_tls.S[3][1]_esd      ? 
_pdbx_refine_tls.S[3][2]          0.0501 
_pdbx_refine_tls.S[3][2]_esd      ? 
_pdbx_refine_tls.S[3][3]          0.1236 
_pdbx_refine_tls.S[3][3]_esd      ? 
# 
_pdbx_refine_tls_group.id                  1 
_pdbx_refine_tls_group.pdbx_refine_id      'X-RAY DIFFRACTION' 
_pdbx_refine_tls_group.refine_tls_id       1 
_pdbx_refine_tls_group.beg_label_asym_id   ? 
_pdbx_refine_tls_group.beg_label_seq_id    ? 
_pdbx_refine_tls_group.beg_auth_asym_id    A 
_pdbx_refine_tls_group.beg_auth_seq_id     394 
_pdbx_refine_tls_group.beg_PDB_ins_code    ? 
_pdbx_refine_tls_group.end_label_asym_id   ? 
_pdbx_refine_tls_group.end_label_seq_id    ? 
_pdbx_refine_tls_group.end_auth_asym_id    A 
_pdbx_refine_tls_group.end_auth_seq_id     801 
_pdbx_refine_tls_group.end_PDB_ins_code    ? 
_pdbx_refine_tls_group.selection           ? 
_pdbx_refine_tls_group.selection_details   ? 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 374 ? A MET 1   
2  1 Y 1 A HIS 375 ? A HIS 2   
3  1 Y 1 A HIS 376 ? A HIS 3   
4  1 Y 1 A HIS 377 ? A HIS 4   
5  1 Y 1 A HIS 378 ? A HIS 5   
6  1 Y 1 A HIS 379 ? A HIS 6   
7  1 Y 1 A HIS 380 ? A HIS 7   
8  1 Y 1 A SER 381 ? A SER 8   
9  1 Y 1 A SER 382 ? A SER 9   
10 1 Y 1 A GLY 383 ? A GLY 10  
11 1 Y 1 A ARG 384 ? A ARG 11  
12 1 Y 1 A GLU 385 ? A GLU 12  
13 1 Y 1 A ASN 386 ? A ASN 13  
14 1 Y 1 A LEU 387 ? A LEU 14  
15 1 Y 1 A TYR 388 ? A TYR 15  
16 1 Y 1 A PHE 389 ? A PHE 16  
17 1 Y 1 A GLN 390 ? A GLN 17  
18 1 Y 1 A GLY 391 ? A GLY 18  
19 1 Y 1 A PRO 392 ? A PRO 19  
20 1 Y 1 A GLU 393 ? A GLU 20  
21 1 Y 1 A THR 520 ? A THR 147 
22 1 Y 1 A SER 521 ? A SER 148 
23 1 Y 1 A GLN 522 ? A GLN 149 
24 1 Y 1 A VAL 523 ? A VAL 150 
25 1 Y 1 A ASP 524 ? A ASP 151 
26 1 Y 1 A PHE 525 ? A PHE 152 
27 1 Y 1 A SER 526 ? A SER 153 
28 1 Y 1 A ALA 527 ? A ALA 154 
29 1 Y 1 A PRO 528 ? A PRO 155 
30 1 Y 1 A ASP 529 ? A ASP 156 
31 1 Y 1 A ILE 530 ? A ILE 157 
32 1 Y 1 A GLY 531 ? A GLY 158 
33 1 Y 1 A SER 532 ? A SER 159 
34 1 Y 1 A LYS 533 ? A LYS 160 
35 1 Y 1 A GLY 534 ? A GLY 161 
36 1 Y 1 A LYS 746 ? A LYS 373 
37 1 Y 1 A ALA 747 ? A ALA 374 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1BLV C5   C Y N 1   
A1BLV C7   C N R 2   
A1BLV C8   C N N 3   
A1BLV C10  C Y N 4   
A1BLV C13  C Y N 5   
A1BLV C15  C Y N 6   
A1BLV C20  C Y N 7   
A1BLV C21  C Y N 8   
A1BLV C22  C Y N 9   
A1BLV C24  C N N 10  
A1BLV C26  C N N 11  
A1BLV C28  C Y N 12  
A1BLV C1   C N N 13  
A1BLV N2   N N N 14  
A1BLV C3   C Y N 15  
A1BLV N4   N Y N 16  
A1BLV N6   N N N 17  
A1BLV C9   C N N 18  
A1BLV C11  C Y N 19  
A1BLV C12  C Y N 20  
A1BLV C14  C Y N 21  
A1BLV C16  C N N 22  
A1BLV N17  N N N 23  
A1BLV C18  C Y N 24  
A1BLV C19  C Y N 25  
A1BLV N23  N N N 26  
A1BLV C25  C N N 27  
A1BLV C27  C N N 28  
A1BLV C29  C Y N 29  
A1BLV C30  C Y N 30  
A1BLV N31  N Y N 31  
A1BLV H1   H N N 32  
A1BLV H2   H N N 33  
A1BLV H3   H N N 34  
A1BLV H4   H N N 35  
A1BLV H5   H N N 36  
A1BLV H6   H N N 37  
A1BLV H7   H N N 38  
A1BLV H8   H N N 39  
A1BLV H9   H N N 40  
A1BLV H10  H N N 41  
A1BLV H11  H N N 42  
A1BLV H12  H N N 43  
A1BLV H13  H N N 44  
A1BLV H14  H N N 45  
A1BLV H15  H N N 46  
A1BLV H16  H N N 47  
A1BLV H17  H N N 48  
A1BLV H18  H N N 49  
A1BLV H19  H N N 50  
A1BLV H20  H N N 51  
A1BLV H21  H N N 52  
A1BLV H22  H N N 53  
A1BLV H23  H N N 54  
A1BLV H24  H N N 55  
A1BLV H25  H N N 56  
A1BLV H26  H N N 57  
ALA   N    N N N 58  
ALA   CA   C N S 59  
ALA   C    C N N 60  
ALA   O    O N N 61  
ALA   CB   C N N 62  
ALA   OXT  O N N 63  
ALA   H    H N N 64  
ALA   H2   H N N 65  
ALA   HA   H N N 66  
ALA   HB1  H N N 67  
ALA   HB2  H N N 68  
ALA   HB3  H N N 69  
ALA   HXT  H N N 70  
ARG   N    N N N 71  
ARG   CA   C N S 72  
ARG   C    C N N 73  
ARG   O    O N N 74  
ARG   CB   C N N 75  
ARG   CG   C N N 76  
ARG   CD   C N N 77  
ARG   NE   N N N 78  
ARG   CZ   C N N 79  
ARG   NH1  N N N 80  
ARG   NH2  N N N 81  
ARG   OXT  O N N 82  
ARG   H    H N N 83  
ARG   H2   H N N 84  
ARG   HA   H N N 85  
ARG   HB2  H N N 86  
ARG   HB3  H N N 87  
ARG   HG2  H N N 88  
ARG   HG3  H N N 89  
ARG   HD2  H N N 90  
ARG   HD3  H N N 91  
ARG   HE   H N N 92  
ARG   HH11 H N N 93  
ARG   HH12 H N N 94  
ARG   HH21 H N N 95  
ARG   HH22 H N N 96  
ARG   HXT  H N N 97  
ASN   N    N N N 98  
ASN   CA   C N S 99  
ASN   C    C N N 100 
ASN   O    O N N 101 
ASN   CB   C N N 102 
ASN   CG   C N N 103 
ASN   OD1  O N N 104 
ASN   ND2  N N N 105 
ASN   OXT  O N N 106 
ASN   H    H N N 107 
ASN   H2   H N N 108 
ASN   HA   H N N 109 
ASN   HB2  H N N 110 
ASN   HB3  H N N 111 
ASN   HD21 H N N 112 
ASN   HD22 H N N 113 
ASN   HXT  H N N 114 
ASP   N    N N N 115 
ASP   CA   C N S 116 
ASP   C    C N N 117 
ASP   O    O N N 118 
ASP   CB   C N N 119 
ASP   CG   C N N 120 
ASP   OD1  O N N 121 
ASP   OD2  O N N 122 
ASP   OXT  O N N 123 
ASP   H    H N N 124 
ASP   H2   H N N 125 
ASP   HA   H N N 126 
ASP   HB2  H N N 127 
ASP   HB3  H N N 128 
ASP   HD2  H N N 129 
ASP   HXT  H N N 130 
CYS   N    N N N 131 
CYS   CA   C N R 132 
CYS   C    C N N 133 
CYS   O    O N N 134 
CYS   CB   C N N 135 
CYS   SG   S N N 136 
CYS   OXT  O N N 137 
CYS   H    H N N 138 
CYS   H2   H N N 139 
CYS   HA   H N N 140 
CYS   HB2  H N N 141 
CYS   HB3  H N N 142 
CYS   HG   H N N 143 
CYS   HXT  H N N 144 
GLN   N    N N N 145 
GLN   CA   C N S 146 
GLN   C    C N N 147 
GLN   O    O N N 148 
GLN   CB   C N N 149 
GLN   CG   C N N 150 
GLN   CD   C N N 151 
GLN   OE1  O N N 152 
GLN   NE2  N N N 153 
GLN   OXT  O N N 154 
GLN   H    H N N 155 
GLN   H2   H N N 156 
GLN   HA   H N N 157 
GLN   HB2  H N N 158 
GLN   HB3  H N N 159 
GLN   HG2  H N N 160 
GLN   HG3  H N N 161 
GLN   HE21 H N N 162 
GLN   HE22 H N N 163 
GLN   HXT  H N N 164 
GLU   N    N N N 165 
GLU   CA   C N S 166 
GLU   C    C N N 167 
GLU   O    O N N 168 
GLU   CB   C N N 169 
GLU   CG   C N N 170 
GLU   CD   C N N 171 
GLU   OE1  O N N 172 
GLU   OE2  O N N 173 
GLU   OXT  O N N 174 
GLU   H    H N N 175 
GLU   H2   H N N 176 
GLU   HA   H N N 177 
GLU   HB2  H N N 178 
GLU   HB3  H N N 179 
GLU   HG2  H N N 180 
GLU   HG3  H N N 181 
GLU   HE2  H N N 182 
GLU   HXT  H N N 183 
GLY   N    N N N 184 
GLY   CA   C N N 185 
GLY   C    C N N 186 
GLY   O    O N N 187 
GLY   OXT  O N N 188 
GLY   H    H N N 189 
GLY   H2   H N N 190 
GLY   HA2  H N N 191 
GLY   HA3  H N N 192 
GLY   HXT  H N N 193 
HIS   N    N N N 194 
HIS   CA   C N S 195 
HIS   C    C N N 196 
HIS   O    O N N 197 
HIS   CB   C N N 198 
HIS   CG   C Y N 199 
HIS   ND1  N Y N 200 
HIS   CD2  C Y N 201 
HIS   CE1  C Y N 202 
HIS   NE2  N Y N 203 
HIS   OXT  O N N 204 
HIS   H    H N N 205 
HIS   H2   H N N 206 
HIS   HA   H N N 207 
HIS   HB2  H N N 208 
HIS   HB3  H N N 209 
HIS   HD1  H N N 210 
HIS   HD2  H N N 211 
HIS   HE1  H N N 212 
HIS   HE2  H N N 213 
HIS   HXT  H N N 214 
HOH   O    O N N 215 
HOH   H1   H N N 216 
HOH   H2   H N N 217 
ILE   N    N N N 218 
ILE   CA   C N S 219 
ILE   C    C N N 220 
ILE   O    O N N 221 
ILE   CB   C N S 222 
ILE   CG1  C N N 223 
ILE   CG2  C N N 224 
ILE   CD1  C N N 225 
ILE   OXT  O N N 226 
ILE   H    H N N 227 
ILE   H2   H N N 228 
ILE   HA   H N N 229 
ILE   HB   H N N 230 
ILE   HG12 H N N 231 
ILE   HG13 H N N 232 
ILE   HG21 H N N 233 
ILE   HG22 H N N 234 
ILE   HG23 H N N 235 
ILE   HD11 H N N 236 
ILE   HD12 H N N 237 
ILE   HD13 H N N 238 
ILE   HXT  H N N 239 
LEU   N    N N N 240 
LEU   CA   C N S 241 
LEU   C    C N N 242 
LEU   O    O N N 243 
LEU   CB   C N N 244 
LEU   CG   C N N 245 
LEU   CD1  C N N 246 
LEU   CD2  C N N 247 
LEU   OXT  O N N 248 
LEU   H    H N N 249 
LEU   H2   H N N 250 
LEU   HA   H N N 251 
LEU   HB2  H N N 252 
LEU   HB3  H N N 253 
LEU   HG   H N N 254 
LEU   HD11 H N N 255 
LEU   HD12 H N N 256 
LEU   HD13 H N N 257 
LEU   HD21 H N N 258 
LEU   HD22 H N N 259 
LEU   HD23 H N N 260 
LEU   HXT  H N N 261 
LYS   N    N N N 262 
LYS   CA   C N S 263 
LYS   C    C N N 264 
LYS   O    O N N 265 
LYS   CB   C N N 266 
LYS   CG   C N N 267 
LYS   CD   C N N 268 
LYS   CE   C N N 269 
LYS   NZ   N N N 270 
LYS   OXT  O N N 271 
LYS   H    H N N 272 
LYS   H2   H N N 273 
LYS   HA   H N N 274 
LYS   HB2  H N N 275 
LYS   HB3  H N N 276 
LYS   HG2  H N N 277 
LYS   HG3  H N N 278 
LYS   HD2  H N N 279 
LYS   HD3  H N N 280 
LYS   HE2  H N N 281 
LYS   HE3  H N N 282 
LYS   HZ1  H N N 283 
LYS   HZ2  H N N 284 
LYS   HZ3  H N N 285 
LYS   HXT  H N N 286 
MET   N    N N N 287 
MET   CA   C N S 288 
MET   C    C N N 289 
MET   O    O N N 290 
MET   CB   C N N 291 
MET   CG   C N N 292 
MET   SD   S N N 293 
MET   CE   C N N 294 
MET   OXT  O N N 295 
MET   H    H N N 296 
MET   H2   H N N 297 
MET   HA   H N N 298 
MET   HB2  H N N 299 
MET   HB3  H N N 300 
MET   HG2  H N N 301 
MET   HG3  H N N 302 
MET   HE1  H N N 303 
MET   HE2  H N N 304 
MET   HE3  H N N 305 
MET   HXT  H N N 306 
PHE   N    N N N 307 
PHE   CA   C N S 308 
PHE   C    C N N 309 
PHE   O    O N N 310 
PHE   CB   C N N 311 
PHE   CG   C Y N 312 
PHE   CD1  C Y N 313 
PHE   CD2  C Y N 314 
PHE   CE1  C Y N 315 
PHE   CE2  C Y N 316 
PHE   CZ   C Y N 317 
PHE   OXT  O N N 318 
PHE   H    H N N 319 
PHE   H2   H N N 320 
PHE   HA   H N N 321 
PHE   HB2  H N N 322 
PHE   HB3  H N N 323 
PHE   HD1  H N N 324 
PHE   HD2  H N N 325 
PHE   HE1  H N N 326 
PHE   HE2  H N N 327 
PHE   HZ   H N N 328 
PHE   HXT  H N N 329 
PRO   N    N N N 330 
PRO   CA   C N S 331 
PRO   C    C N N 332 
PRO   O    O N N 333 
PRO   CB   C N N 334 
PRO   CG   C N N 335 
PRO   CD   C N N 336 
PRO   OXT  O N N 337 
PRO   H    H N N 338 
PRO   HA   H N N 339 
PRO   HB2  H N N 340 
PRO   HB3  H N N 341 
PRO   HG2  H N N 342 
PRO   HG3  H N N 343 
PRO   HD2  H N N 344 
PRO   HD3  H N N 345 
PRO   HXT  H N N 346 
SER   N    N N N 347 
SER   CA   C N S 348 
SER   C    C N N 349 
SER   O    O N N 350 
SER   CB   C N N 351 
SER   OG   O N N 352 
SER   OXT  O N N 353 
SER   H    H N N 354 
SER   H2   H N N 355 
SER   HA   H N N 356 
SER   HB2  H N N 357 
SER   HB3  H N N 358 
SER   HG   H N N 359 
SER   HXT  H N N 360 
THR   N    N N N 361 
THR   CA   C N S 362 
THR   C    C N N 363 
THR   O    O N N 364 
THR   CB   C N R 365 
THR   OG1  O N N 366 
THR   CG2  C N N 367 
THR   OXT  O N N 368 
THR   H    H N N 369 
THR   H2   H N N 370 
THR   HA   H N N 371 
THR   HB   H N N 372 
THR   HG1  H N N 373 
THR   HG21 H N N 374 
THR   HG22 H N N 375 
THR   HG23 H N N 376 
THR   HXT  H N N 377 
TRP   N    N N N 378 
TRP   CA   C N S 379 
TRP   C    C N N 380 
TRP   O    O N N 381 
TRP   CB   C N N 382 
TRP   CG   C Y N 383 
TRP   CD1  C Y N 384 
TRP   CD2  C Y N 385 
TRP   NE1  N Y N 386 
TRP   CE2  C Y N 387 
TRP   CE3  C Y N 388 
TRP   CZ2  C Y N 389 
TRP   CZ3  C Y N 390 
TRP   CH2  C Y N 391 
TRP   OXT  O N N 392 
TRP   H    H N N 393 
TRP   H2   H N N 394 
TRP   HA   H N N 395 
TRP   HB2  H N N 396 
TRP   HB3  H N N 397 
TRP   HD1  H N N 398 
TRP   HE1  H N N 399 
TRP   HE3  H N N 400 
TRP   HZ2  H N N 401 
TRP   HZ3  H N N 402 
TRP   HH2  H N N 403 
TRP   HXT  H N N 404 
TYR   N    N N N 405 
TYR   CA   C N S 406 
TYR   C    C N N 407 
TYR   O    O N N 408 
TYR   CB   C N N 409 
TYR   CG   C Y N 410 
TYR   CD1  C Y N 411 
TYR   CD2  C Y N 412 
TYR   CE1  C Y N 413 
TYR   CE2  C Y N 414 
TYR   CZ   C Y N 415 
TYR   OH   O N N 416 
TYR   OXT  O N N 417 
TYR   H    H N N 418 
TYR   H2   H N N 419 
TYR   HA   H N N 420 
TYR   HB2  H N N 421 
TYR   HB3  H N N 422 
TYR   HD1  H N N 423 
TYR   HD2  H N N 424 
TYR   HE1  H N N 425 
TYR   HE2  H N N 426 
TYR   HH   H N N 427 
TYR   HXT  H N N 428 
VAL   N    N N N 429 
VAL   CA   C N S 430 
VAL   C    C N N 431 
VAL   O    O N N 432 
VAL   CB   C N N 433 
VAL   CG1  C N N 434 
VAL   CG2  C N N 435 
VAL   OXT  O N N 436 
VAL   H    H N N 437 
VAL   H2   H N N 438 
VAL   HA   H N N 439 
VAL   HB   H N N 440 
VAL   HG11 H N N 441 
VAL   HG12 H N N 442 
VAL   HG13 H N N 443 
VAL   HG21 H N N 444 
VAL   HG22 H N N 445 
VAL   HG23 H N N 446 
VAL   HXT  H N N 447 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1BLV C26 C27  sing N N 1   
A1BLV C26 C25  sing N N 2   
A1BLV C27 N23  sing N N 3   
A1BLV C28 C29  doub Y N 4   
A1BLV C28 C22  sing Y N 5   
A1BLV C29 C30  sing Y N 6   
A1BLV C25 C24  sing N N 7   
A1BLV N23 C22  sing N N 8   
A1BLV N23 C24  sing N N 9   
A1BLV C22 C21  doub Y N 10  
A1BLV C30 C20  doub Y N 11  
A1BLV C21 C20  sing Y N 12  
A1BLV C20 C19  sing N N 13  
A1BLV C19 C18  doub Y N 14  
A1BLV C19 N31  sing Y N 15  
A1BLV C18 C5   sing Y N 16  
A1BLV N31 C3   doub Y N 17  
A1BLV C5  N6   sing N N 18  
A1BLV C5  N4   doub Y N 19  
A1BLV C3  N4   sing Y N 20  
A1BLV C3  N2   sing N N 21  
A1BLV N6  C7   sing N N 22  
A1BLV N2  C1   sing N N 23  
A1BLV C8  C7   sing N N 24  
A1BLV C8  C9   sing N N 25  
A1BLV C7  C11  sing N N 26  
A1BLV C11 C12  doub Y N 27  
A1BLV C11 C10  sing Y N 28  
A1BLV C9  C10  sing N N 29  
A1BLV C12 C13  sing Y N 30  
A1BLV C10 C15  doub Y N 31  
A1BLV C13 C14  doub Y N 32  
A1BLV C15 C14  sing Y N 33  
A1BLV C15 C16  sing N N 34  
A1BLV C16 N17  trip N N 35  
A1BLV C7  H1   sing N N 36  
A1BLV C8  H2   sing N N 37  
A1BLV C8  H3   sing N N 38  
A1BLV C13 H4   sing N N 39  
A1BLV C21 H5   sing N N 40  
A1BLV C24 H6   sing N N 41  
A1BLV C24 H7   sing N N 42  
A1BLV C26 H8   sing N N 43  
A1BLV C26 H9   sing N N 44  
A1BLV C28 H10  sing N N 45  
A1BLV C1  H11  sing N N 46  
A1BLV C1  H12  sing N N 47  
A1BLV C1  H13  sing N N 48  
A1BLV N2  H14  sing N N 49  
A1BLV N6  H15  sing N N 50  
A1BLV C9  H16  sing N N 51  
A1BLV C9  H17  sing N N 52  
A1BLV C12 H18  sing N N 53  
A1BLV C14 H19  sing N N 54  
A1BLV C18 H20  sing N N 55  
A1BLV C25 H21  sing N N 56  
A1BLV C25 H22  sing N N 57  
A1BLV C27 H23  sing N N 58  
A1BLV C27 H24  sing N N 59  
A1BLV C29 H25  sing N N 60  
A1BLV C30 H26  sing N N 61  
ALA   N   CA   sing N N 62  
ALA   N   H    sing N N 63  
ALA   N   H2   sing N N 64  
ALA   CA  C    sing N N 65  
ALA   CA  CB   sing N N 66  
ALA   CA  HA   sing N N 67  
ALA   C   O    doub N N 68  
ALA   C   OXT  sing N N 69  
ALA   CB  HB1  sing N N 70  
ALA   CB  HB2  sing N N 71  
ALA   CB  HB3  sing N N 72  
ALA   OXT HXT  sing N N 73  
ARG   N   CA   sing N N 74  
ARG   N   H    sing N N 75  
ARG   N   H2   sing N N 76  
ARG   CA  C    sing N N 77  
ARG   CA  CB   sing N N 78  
ARG   CA  HA   sing N N 79  
ARG   C   O    doub N N 80  
ARG   C   OXT  sing N N 81  
ARG   CB  CG   sing N N 82  
ARG   CB  HB2  sing N N 83  
ARG   CB  HB3  sing N N 84  
ARG   CG  CD   sing N N 85  
ARG   CG  HG2  sing N N 86  
ARG   CG  HG3  sing N N 87  
ARG   CD  NE   sing N N 88  
ARG   CD  HD2  sing N N 89  
ARG   CD  HD3  sing N N 90  
ARG   NE  CZ   sing N N 91  
ARG   NE  HE   sing N N 92  
ARG   CZ  NH1  sing N N 93  
ARG   CZ  NH2  doub N N 94  
ARG   NH1 HH11 sing N N 95  
ARG   NH1 HH12 sing N N 96  
ARG   NH2 HH21 sing N N 97  
ARG   NH2 HH22 sing N N 98  
ARG   OXT HXT  sing N N 99  
ASN   N   CA   sing N N 100 
ASN   N   H    sing N N 101 
ASN   N   H2   sing N N 102 
ASN   CA  C    sing N N 103 
ASN   CA  CB   sing N N 104 
ASN   CA  HA   sing N N 105 
ASN   C   O    doub N N 106 
ASN   C   OXT  sing N N 107 
ASN   CB  CG   sing N N 108 
ASN   CB  HB2  sing N N 109 
ASN   CB  HB3  sing N N 110 
ASN   CG  OD1  doub N N 111 
ASN   CG  ND2  sing N N 112 
ASN   ND2 HD21 sing N N 113 
ASN   ND2 HD22 sing N N 114 
ASN   OXT HXT  sing N N 115 
ASP   N   CA   sing N N 116 
ASP   N   H    sing N N 117 
ASP   N   H2   sing N N 118 
ASP   CA  C    sing N N 119 
ASP   CA  CB   sing N N 120 
ASP   CA  HA   sing N N 121 
ASP   C   O    doub N N 122 
ASP   C   OXT  sing N N 123 
ASP   CB  CG   sing N N 124 
ASP   CB  HB2  sing N N 125 
ASP   CB  HB3  sing N N 126 
ASP   CG  OD1  doub N N 127 
ASP   CG  OD2  sing N N 128 
ASP   OD2 HD2  sing N N 129 
ASP   OXT HXT  sing N N 130 
CYS   N   CA   sing N N 131 
CYS   N   H    sing N N 132 
CYS   N   H2   sing N N 133 
CYS   CA  C    sing N N 134 
CYS   CA  CB   sing N N 135 
CYS   CA  HA   sing N N 136 
CYS   C   O    doub N N 137 
CYS   C   OXT  sing N N 138 
CYS   CB  SG   sing N N 139 
CYS   CB  HB2  sing N N 140 
CYS   CB  HB3  sing N N 141 
CYS   SG  HG   sing N N 142 
CYS   OXT HXT  sing N N 143 
GLN   N   CA   sing N N 144 
GLN   N   H    sing N N 145 
GLN   N   H2   sing N N 146 
GLN   CA  C    sing N N 147 
GLN   CA  CB   sing N N 148 
GLN   CA  HA   sing N N 149 
GLN   C   O    doub N N 150 
GLN   C   OXT  sing N N 151 
GLN   CB  CG   sing N N 152 
GLN   CB  HB2  sing N N 153 
GLN   CB  HB3  sing N N 154 
GLN   CG  CD   sing N N 155 
GLN   CG  HG2  sing N N 156 
GLN   CG  HG3  sing N N 157 
GLN   CD  OE1  doub N N 158 
GLN   CD  NE2  sing N N 159 
GLN   NE2 HE21 sing N N 160 
GLN   NE2 HE22 sing N N 161 
GLN   OXT HXT  sing N N 162 
GLU   N   CA   sing N N 163 
GLU   N   H    sing N N 164 
GLU   N   H2   sing N N 165 
GLU   CA  C    sing N N 166 
GLU   CA  CB   sing N N 167 
GLU   CA  HA   sing N N 168 
GLU   C   O    doub N N 169 
GLU   C   OXT  sing N N 170 
GLU   CB  CG   sing N N 171 
GLU   CB  HB2  sing N N 172 
GLU   CB  HB3  sing N N 173 
GLU   CG  CD   sing N N 174 
GLU   CG  HG2  sing N N 175 
GLU   CG  HG3  sing N N 176 
GLU   CD  OE1  doub N N 177 
GLU   CD  OE2  sing N N 178 
GLU   OE2 HE2  sing N N 179 
GLU   OXT HXT  sing N N 180 
GLY   N   CA   sing N N 181 
GLY   N   H    sing N N 182 
GLY   N   H2   sing N N 183 
GLY   CA  C    sing N N 184 
GLY   CA  HA2  sing N N 185 
GLY   CA  HA3  sing N N 186 
GLY   C   O    doub N N 187 
GLY   C   OXT  sing N N 188 
GLY   OXT HXT  sing N N 189 
HIS   N   CA   sing N N 190 
HIS   N   H    sing N N 191 
HIS   N   H2   sing N N 192 
HIS   CA  C    sing N N 193 
HIS   CA  CB   sing N N 194 
HIS   CA  HA   sing N N 195 
HIS   C   O    doub N N 196 
HIS   C   OXT  sing N N 197 
HIS   CB  CG   sing N N 198 
HIS   CB  HB2  sing N N 199 
HIS   CB  HB3  sing N N 200 
HIS   CG  ND1  sing Y N 201 
HIS   CG  CD2  doub Y N 202 
HIS   ND1 CE1  doub Y N 203 
HIS   ND1 HD1  sing N N 204 
HIS   CD2 NE2  sing Y N 205 
HIS   CD2 HD2  sing N N 206 
HIS   CE1 NE2  sing Y N 207 
HIS   CE1 HE1  sing N N 208 
HIS   NE2 HE2  sing N N 209 
HIS   OXT HXT  sing N N 210 
HOH   O   H1   sing N N 211 
HOH   O   H2   sing N N 212 
ILE   N   CA   sing N N 213 
ILE   N   H    sing N N 214 
ILE   N   H2   sing N N 215 
ILE   CA  C    sing N N 216 
ILE   CA  CB   sing N N 217 
ILE   CA  HA   sing N N 218 
ILE   C   O    doub N N 219 
ILE   C   OXT  sing N N 220 
ILE   CB  CG1  sing N N 221 
ILE   CB  CG2  sing N N 222 
ILE   CB  HB   sing N N 223 
ILE   CG1 CD1  sing N N 224 
ILE   CG1 HG12 sing N N 225 
ILE   CG1 HG13 sing N N 226 
ILE   CG2 HG21 sing N N 227 
ILE   CG2 HG22 sing N N 228 
ILE   CG2 HG23 sing N N 229 
ILE   CD1 HD11 sing N N 230 
ILE   CD1 HD12 sing N N 231 
ILE   CD1 HD13 sing N N 232 
ILE   OXT HXT  sing N N 233 
LEU   N   CA   sing N N 234 
LEU   N   H    sing N N 235 
LEU   N   H2   sing N N 236 
LEU   CA  C    sing N N 237 
LEU   CA  CB   sing N N 238 
LEU   CA  HA   sing N N 239 
LEU   C   O    doub N N 240 
LEU   C   OXT  sing N N 241 
LEU   CB  CG   sing N N 242 
LEU   CB  HB2  sing N N 243 
LEU   CB  HB3  sing N N 244 
LEU   CG  CD1  sing N N 245 
LEU   CG  CD2  sing N N 246 
LEU   CG  HG   sing N N 247 
LEU   CD1 HD11 sing N N 248 
LEU   CD1 HD12 sing N N 249 
LEU   CD1 HD13 sing N N 250 
LEU   CD2 HD21 sing N N 251 
LEU   CD2 HD22 sing N N 252 
LEU   CD2 HD23 sing N N 253 
LEU   OXT HXT  sing N N 254 
LYS   N   CA   sing N N 255 
LYS   N   H    sing N N 256 
LYS   N   H2   sing N N 257 
LYS   CA  C    sing N N 258 
LYS   CA  CB   sing N N 259 
LYS   CA  HA   sing N N 260 
LYS   C   O    doub N N 261 
LYS   C   OXT  sing N N 262 
LYS   CB  CG   sing N N 263 
LYS   CB  HB2  sing N N 264 
LYS   CB  HB3  sing N N 265 
LYS   CG  CD   sing N N 266 
LYS   CG  HG2  sing N N 267 
LYS   CG  HG3  sing N N 268 
LYS   CD  CE   sing N N 269 
LYS   CD  HD2  sing N N 270 
LYS   CD  HD3  sing N N 271 
LYS   CE  NZ   sing N N 272 
LYS   CE  HE2  sing N N 273 
LYS   CE  HE3  sing N N 274 
LYS   NZ  HZ1  sing N N 275 
LYS   NZ  HZ2  sing N N 276 
LYS   NZ  HZ3  sing N N 277 
LYS   OXT HXT  sing N N 278 
MET   N   CA   sing N N 279 
MET   N   H    sing N N 280 
MET   N   H2   sing N N 281 
MET   CA  C    sing N N 282 
MET   CA  CB   sing N N 283 
MET   CA  HA   sing N N 284 
MET   C   O    doub N N 285 
MET   C   OXT  sing N N 286 
MET   CB  CG   sing N N 287 
MET   CB  HB2  sing N N 288 
MET   CB  HB3  sing N N 289 
MET   CG  SD   sing N N 290 
MET   CG  HG2  sing N N 291 
MET   CG  HG3  sing N N 292 
MET   SD  CE   sing N N 293 
MET   CE  HE1  sing N N 294 
MET   CE  HE2  sing N N 295 
MET   CE  HE3  sing N N 296 
MET   OXT HXT  sing N N 297 
PHE   N   CA   sing N N 298 
PHE   N   H    sing N N 299 
PHE   N   H2   sing N N 300 
PHE   CA  C    sing N N 301 
PHE   CA  CB   sing N N 302 
PHE   CA  HA   sing N N 303 
PHE   C   O    doub N N 304 
PHE   C   OXT  sing N N 305 
PHE   CB  CG   sing N N 306 
PHE   CB  HB2  sing N N 307 
PHE   CB  HB3  sing N N 308 
PHE   CG  CD1  doub Y N 309 
PHE   CG  CD2  sing Y N 310 
PHE   CD1 CE1  sing Y N 311 
PHE   CD1 HD1  sing N N 312 
PHE   CD2 CE2  doub Y N 313 
PHE   CD2 HD2  sing N N 314 
PHE   CE1 CZ   doub Y N 315 
PHE   CE1 HE1  sing N N 316 
PHE   CE2 CZ   sing Y N 317 
PHE   CE2 HE2  sing N N 318 
PHE   CZ  HZ   sing N N 319 
PHE   OXT HXT  sing N N 320 
PRO   N   CA   sing N N 321 
PRO   N   CD   sing N N 322 
PRO   N   H    sing N N 323 
PRO   CA  C    sing N N 324 
PRO   CA  CB   sing N N 325 
PRO   CA  HA   sing N N 326 
PRO   C   O    doub N N 327 
PRO   C   OXT  sing N N 328 
PRO   CB  CG   sing N N 329 
PRO   CB  HB2  sing N N 330 
PRO   CB  HB3  sing N N 331 
PRO   CG  CD   sing N N 332 
PRO   CG  HG2  sing N N 333 
PRO   CG  HG3  sing N N 334 
PRO   CD  HD2  sing N N 335 
PRO   CD  HD3  sing N N 336 
PRO   OXT HXT  sing N N 337 
SER   N   CA   sing N N 338 
SER   N   H    sing N N 339 
SER   N   H2   sing N N 340 
SER   CA  C    sing N N 341 
SER   CA  CB   sing N N 342 
SER   CA  HA   sing N N 343 
SER   C   O    doub N N 344 
SER   C   OXT  sing N N 345 
SER   CB  OG   sing N N 346 
SER   CB  HB2  sing N N 347 
SER   CB  HB3  sing N N 348 
SER   OG  HG   sing N N 349 
SER   OXT HXT  sing N N 350 
THR   N   CA   sing N N 351 
THR   N   H    sing N N 352 
THR   N   H2   sing N N 353 
THR   CA  C    sing N N 354 
THR   CA  CB   sing N N 355 
THR   CA  HA   sing N N 356 
THR   C   O    doub N N 357 
THR   C   OXT  sing N N 358 
THR   CB  OG1  sing N N 359 
THR   CB  CG2  sing N N 360 
THR   CB  HB   sing N N 361 
THR   OG1 HG1  sing N N 362 
THR   CG2 HG21 sing N N 363 
THR   CG2 HG22 sing N N 364 
THR   CG2 HG23 sing N N 365 
THR   OXT HXT  sing N N 366 
TRP   N   CA   sing N N 367 
TRP   N   H    sing N N 368 
TRP   N   H2   sing N N 369 
TRP   CA  C    sing N N 370 
TRP   CA  CB   sing N N 371 
TRP   CA  HA   sing N N 372 
TRP   C   O    doub N N 373 
TRP   C   OXT  sing N N 374 
TRP   CB  CG   sing N N 375 
TRP   CB  HB2  sing N N 376 
TRP   CB  HB3  sing N N 377 
TRP   CG  CD1  doub Y N 378 
TRP   CG  CD2  sing Y N 379 
TRP   CD1 NE1  sing Y N 380 
TRP   CD1 HD1  sing N N 381 
TRP   CD2 CE2  doub Y N 382 
TRP   CD2 CE3  sing Y N 383 
TRP   NE1 CE2  sing Y N 384 
TRP   NE1 HE1  sing N N 385 
TRP   CE2 CZ2  sing Y N 386 
TRP   CE3 CZ3  doub Y N 387 
TRP   CE3 HE3  sing N N 388 
TRP   CZ2 CH2  doub Y N 389 
TRP   CZ2 HZ2  sing N N 390 
TRP   CZ3 CH2  sing Y N 391 
TRP   CZ3 HZ3  sing N N 392 
TRP   CH2 HH2  sing N N 393 
TRP   OXT HXT  sing N N 394 
TYR   N   CA   sing N N 395 
TYR   N   H    sing N N 396 
TYR   N   H2   sing N N 397 
TYR   CA  C    sing N N 398 
TYR   CA  CB   sing N N 399 
TYR   CA  HA   sing N N 400 
TYR   C   O    doub N N 401 
TYR   C   OXT  sing N N 402 
TYR   CB  CG   sing N N 403 
TYR   CB  HB2  sing N N 404 
TYR   CB  HB3  sing N N 405 
TYR   CG  CD1  doub Y N 406 
TYR   CG  CD2  sing Y N 407 
TYR   CD1 CE1  sing Y N 408 
TYR   CD1 HD1  sing N N 409 
TYR   CD2 CE2  doub Y N 410 
TYR   CD2 HD2  sing N N 411 
TYR   CE1 CZ   doub Y N 412 
TYR   CE1 HE1  sing N N 413 
TYR   CE2 CZ   sing Y N 414 
TYR   CE2 HE2  sing N N 415 
TYR   CZ  OH   sing N N 416 
TYR   OH  HH   sing N N 417 
TYR   OXT HXT  sing N N 418 
VAL   N   CA   sing N N 419 
VAL   N   H    sing N N 420 
VAL   N   H2   sing N N 421 
VAL   CA  C    sing N N 422 
VAL   CA  CB   sing N N 423 
VAL   CA  HA   sing N N 424 
VAL   C   O    doub N N 425 
VAL   C   OXT  sing N N 426 
VAL   CB  CG1  sing N N 427 
VAL   CB  CG2  sing N N 428 
VAL   CB  HB   sing N N 429 
VAL   CG1 HG11 sing N N 430 
VAL   CG1 HG12 sing N N 431 
VAL   CG1 HG13 sing N N 432 
VAL   CG2 HG21 sing N N 433 
VAL   CG2 HG22 sing N N 434 
VAL   CG2 HG23 sing N N 435 
VAL   OXT HXT  sing N N 436 
# 
_pdbx_audit_support.funding_organization   'Other private' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6VYC 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9MK7 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.012626 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   -0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.007562 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   -0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.008454 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
X 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . GLN   A 1 21  ? -31.691 -34.462 17.117  1.00 96.23  ? 394 GLN   A N   1 
ATOM   2    C CA  . GLN   A 1 21  ? -30.449 -34.237 16.329  1.00 94.17  ? 394 GLN   A CA  1 
ATOM   3    C C   . GLN   A 1 21  ? -30.401 -35.216 15.148  1.00 96.21  ? 394 GLN   A C   1 
ATOM   4    O O   . GLN   A 1 21  ? -29.783 -36.280 15.231  1.00 102.95 ? 394 GLN   A O   1 
ATOM   5    C CB  . GLN   A 1 21  ? -29.215 -34.331 17.231  1.00 94.90  ? 394 GLN   A CB  1 
ATOM   6    N N   . PRO   A 1 22  ? -31.027 -34.867 13.992  1.00 94.26  ? 395 PRO   A N   1 
ATOM   7    C CA  . PRO   A 1 22  ? -30.800 -35.580 12.723  1.00 93.13  ? 395 PRO   A CA  1 
ATOM   8    C C   . PRO   A 1 22  ? -29.453 -35.276 12.024  1.00 87.49  ? 395 PRO   A C   1 
ATOM   9    O O   . PRO   A 1 22  ? -29.041 -35.964 11.029  1.00 88.88  ? 395 PRO   A O   1 
ATOM   10   C CB  . PRO   A 1 22  ? -31.982 -35.153 11.805  1.00 84.21  ? 395 PRO   A CB  1 
ATOM   11   C CG  . PRO   A 1 22  ? -32.703 -34.029 12.553  1.00 86.30  ? 395 PRO   A CG  1 
ATOM   12   C CD  . PRO   A 1 22  ? -31.954 -33.737 13.843  1.00 89.97  ? 395 PRO   A CD  1 
ATOM   13   N N   . PHE   A 1 23  ? -28.792 -34.204 12.484  1.00 75.18  ? 396 PHE   A N   1 
ATOM   14   C CA  . PHE   A 1 23  ? -27.485 -33.867 11.959  1.00 71.46  ? 396 PHE   A CA  1 
ATOM   15   C C   . PHE   A 1 23  ? -26.546 -33.483 13.081  1.00 72.48  ? 396 PHE   A C   1 
ATOM   16   O O   . PHE   A 1 23  ? -26.976 -32.971 14.106  1.00 78.53  ? 396 PHE   A O   1 
ATOM   17   C CB  . PHE   A 1 23  ? -27.531 -32.674 11.012  1.00 68.16  ? 396 PHE   A CB  1 
ATOM   18   C CG  . PHE   A 1 23  ? -28.348 -32.949 9.767   1.00 64.69  ? 396 PHE   A CG  1 
ATOM   19   C CD1 . PHE   A 1 23  ? -27.805 -33.672 8.709   1.00 64.31  ? 396 PHE   A CD1 1 
ATOM   20   C CD2 . PHE   A 1 23  ? -29.673 -32.529 9.678   1.00 61.36  ? 396 PHE   A CD2 1 
ATOM   21   C CE1 . PHE   A 1 23  ? -28.570 -33.983 7.598   1.00 64.81  ? 396 PHE   A CE1 1 
ATOM   22   C CE2 . PHE   A 1 23  ? -30.426 -32.818 8.558   1.00 64.23  ? 396 PHE   A CE2 1 
ATOM   23   C CZ  . PHE   A 1 23  ? -29.868 -33.532 7.510   1.00 67.21  ? 396 PHE   A CZ  1 
ATOM   24   N N   . ILE   A 1 24  ? -25.255 -33.716 12.833  1.00 74.35  ? 397 ILE   A N   1 
ATOM   25   C CA  . ILE   A 1 24  ? -24.197 -33.212 13.689  1.00 77.81  ? 397 ILE   A CA  1 
ATOM   26   C C   . ILE   A 1 24  ? -23.434 -32.152 12.912  1.00 72.11  ? 397 ILE   A C   1 
ATOM   27   O O   . ILE   A 1 24  ? -23.049 -32.372 11.767  1.00 71.47  ? 397 ILE   A O   1 
ATOM   28   C CB  . ILE   A 1 24  ? -23.276 -34.349 14.174  1.00 84.24  ? 397 ILE   A CB  1 
ATOM   29   C CG1 . ILE   A 1 24  ? -24.032 -35.350 15.079  1.00 89.63  ? 397 ILE   A CG1 1 
ATOM   30   C CG2 . ILE   A 1 24  ? -22.040 -33.775 14.873  1.00 86.63  ? 397 ILE   A CG2 1 
ATOM   31   C CD1 . ILE   A 1 24  ? -23.669 -36.807 14.831  1.00 93.84  ? 397 ILE   A CD1 1 
ATOM   32   N N   . VAL   A 1 25  ? -23.237 -31.005 13.555  1.00 70.58  ? 398 VAL   A N   1 
ATOM   33   C CA  . VAL   A 1 25  ? -22.512 -29.895 12.973  1.00 71.27  ? 398 VAL   A CA  1 
ATOM   34   C C   . VAL   A 1 25  ? -21.015 -30.073 13.208  1.00 70.00  ? 398 VAL   A C   1 
ATOM   35   O O   . VAL   A 1 25  ? -20.547 -29.833 14.310  1.00 71.52  ? 398 VAL   A O   1 
ATOM   36   C CB  . VAL   A 1 25  ? -23.017 -28.596 13.621  1.00 75.36  ? 398 VAL   A CB  1 
ATOM   37   C CG1 . VAL   A 1 25  ? -22.324 -27.371 13.033  1.00 74.00  ? 398 VAL   A CG1 1 
ATOM   38   C CG2 . VAL   A 1 25  ? -24.535 -28.483 13.522  1.00 76.35  ? 398 VAL   A CG2 1 
ATOM   39   N N   . LEU   A 1 26  ? -20.261 -30.426 12.154  1.00 67.70  ? 399 LEU   A N   1 
ATOM   40   C CA  . LEU   A 1 26  ? -18.816 -30.614 12.274  1.00 67.71  ? 399 LEU   A CA  1 
ATOM   41   C C   . LEU   A 1 26  ? -18.080 -29.265 12.335  1.00 64.70  ? 399 LEU   A C   1 
ATOM   42   O O   . LEU   A 1 26  ? -16.993 -29.190 12.897  1.00 66.42  ? 399 LEU   A O   1 
ATOM   43   C CB  . LEU   A 1 26  ? -18.267 -31.483 11.142  1.00 67.62  ? 399 LEU   A CB  1 
ATOM   44   C CG  . LEU   A 1 26  ? -18.756 -32.934 11.079  1.00 69.38  ? 399 LEU   A CG  1 
ATOM   45   C CD1 . LEU   A 1 26  ? -18.171 -33.630 9.839   1.00 69.32  ? 399 LEU   A CD1 1 
ATOM   46   C CD2 . LEU   A 1 26  ? -18.425 -33.712 12.337  1.00 71.35  ? 399 LEU   A CD2 1 
ATOM   47   N N   . GLY   A 1 27  ? -18.669 -28.197 11.773  1.00 61.70  ? 400 GLY   A N   1 
ATOM   48   C CA  . GLY   A 1 27  ? -18.051 -26.875 11.847  1.00 62.16  ? 400 GLY   A CA  1 
ATOM   49   C C   . GLY   A 1 27  ? -18.785 -25.818 11.012  1.00 60.10  ? 400 GLY   A C   1 
ATOM   50   O O   . GLY   A 1 27  ? -19.571 -26.135 10.111  1.00 56.05  ? 400 GLY   A O   1 
ATOM   51   N N   . GLN   A 1 28  ? -18.510 -24.550 11.349  1.00 61.15  ? 401 GLN   A N   1 
ATOM   52   C CA  . GLN   A 1 28  ? -18.976 -23.406 10.590  1.00 60.59  ? 401 GLN   A CA  1 
ATOM   53   C C   . GLN   A 1 28  ? -17.796 -22.484 10.266  1.00 58.38  ? 401 GLN   A C   1 
ATOM   54   O O   . GLN   A 1 28  ? -17.154 -21.969 11.166  1.00 57.37  ? 401 GLN   A O   1 
ATOM   55   C CB  . GLN   A 1 28  ? -20.045 -22.638 11.364  1.00 62.12  ? 401 GLN   A CB  1 
ATOM   56   C CG  . GLN   A 1 28  ? -20.776 -21.624 10.488  1.00 61.71  ? 401 GLN   A CG  1 
ATOM   57   C CD  . GLN   A 1 28  ? -22.081 -21.140 11.071  1.00 60.77  ? 401 GLN   A CD  1 
ATOM   58   O OE1 . GLN   A 1 28  ? -22.111 -20.287 11.964  1.00 65.48  ? 401 GLN   A OE1 1 
ATOM   59   N NE2 . GLN   A 1 28  ? -23.176 -21.677 10.549  1.00 58.92  ? 401 GLN   A NE2 1 
ATOM   60   N N   A GLU   A 1 29  ? -17.555 -22.269 8.967   0.50 54.93  ? 402 GLU   A N   1 
ATOM   61   N N   B GLU   A 1 29  ? -17.520 -22.303 8.966   0.50 56.74  ? 402 GLU   A N   1 
ATOM   62   C CA  A GLU   A 1 29  ? -16.514 -21.363 8.508   0.50 54.10  ? 402 GLU   A CA  1 
ATOM   63   C CA  B GLU   A 1 29  ? -16.510 -21.359 8.507   0.50 56.98  ? 402 GLU   A CA  1 
ATOM   64   C C   A GLU   A 1 29  ? -17.158 -20.265 7.659   0.50 52.93  ? 402 GLU   A C   1 
ATOM   65   C C   B GLU   A 1 29  ? -17.190 -20.232 7.732   0.50 54.60  ? 402 GLU   A C   1 
ATOM   66   O O   A GLU   A 1 29  ? -18.265 -20.432 7.144   0.50 51.12  ? 402 GLU   A O   1 
ATOM   67   O O   B GLU   A 1 29  ? -18.348 -20.351 7.327   0.50 52.85  ? 402 GLU   A O   1 
ATOM   68   C CB  A GLU   A 1 29  ? -15.441 -22.128 7.732   0.50 52.46  ? 402 GLU   A CB  1 
ATOM   69   C CB  B GLU   A 1 29  ? -15.448 -22.007 7.615   0.50 57.05  ? 402 GLU   A CB  1 
ATOM   70   C CG  A GLU   A 1 29  ? -14.947 -23.389 8.441   0.50 52.66  ? 402 GLU   A CG  1 
ATOM   71   C CG  B GLU   A 1 29  ? -14.611 -23.079 8.309   0.50 59.35  ? 402 GLU   A CG  1 
ATOM   72   C CD  A GLU   A 1 29  ? -14.006 -23.141 9.604   0.50 54.35  ? 402 GLU   A CD  1 
ATOM   73   C CD  B GLU   A 1 29  ? -15.201 -24.474 8.236   0.50 58.90  ? 402 GLU   A CD  1 
ATOM   74   O OE1 A GLU   A 1 29  ? -13.495 -22.010 9.726   0.50 53.76  ? 402 GLU   A OE1 1 
ATOM   75   O OE1 B GLU   A 1 29  ? -15.512 -24.966 7.111   0.50 55.12  ? 402 GLU   A OE1 1 
ATOM   76   O OE2 A GLU   A 1 29  ? -13.815 -24.076 10.404  0.50 54.63  ? 402 GLU   A OE2 1 
ATOM   77   O OE2 B GLU   A 1 29  ? -15.336 -25.075 9.330   0.50 64.41  ? 402 GLU   A OE2 1 
ATOM   78   N N   . GLU   A 1 30  ? -16.445 -19.146 7.525   1.00 54.55  ? 403 GLU   A N   1 
ATOM   79   C CA  . GLU   A 1 30  ? -16.968 -17.964 6.862   1.00 54.06  ? 403 GLU   A CA  1 
ATOM   80   C C   . GLU   A 1 30  ? -16.120 -17.662 5.636   1.00 50.31  ? 403 GLU   A C   1 
ATOM   81   O O   . GLU   A 1 30  ? -14.911 -17.553 5.748   1.00 52.27  ? 403 GLU   A O   1 
ATOM   82   C CB  . GLU   A 1 30  ? -16.918 -16.774 7.817   1.00 55.47  ? 403 GLU   A CB  1 
ATOM   83   C CG  . GLU   A 1 30  ? -17.551 -15.509 7.240   1.00 57.37  ? 403 GLU   A CG  1 
ATOM   84   C CD  . GLU   A 1 30  ? -17.710 -14.381 8.239   1.00 58.90  ? 403 GLU   A CD  1 
ATOM   85   O OE1 . GLU   A 1 30  ? -16.944 -13.390 8.170   1.00 60.49  ? 403 GLU   A OE1 1 
ATOM   86   O OE2 . GLU   A 1 30  ? -18.604 -14.517 9.097   1.00 61.71  ? 403 GLU   A OE2 1 
ATOM   87   N N   . TYR   A 1 31  ? -16.775 -17.461 4.492   1.00 48.68  ? 404 TYR   A N   1 
ATOM   88   C CA  . TYR   A 1 31  ? -16.117 -16.868 3.331   1.00 49.43  ? 404 TYR   A CA  1 
ATOM   89   C C   . TYR   A 1 31  ? -16.497 -15.393 3.251   1.00 51.14  ? 404 TYR   A C   1 
ATOM   90   O O   . TYR   A 1 31  ? -17.685 -15.071 3.140   1.00 48.67  ? 404 TYR   A O   1 
ATOM   91   C CB  . TYR   A 1 31  ? -16.503 -17.589 2.051   1.00 45.59  ? 404 TYR   A CB  1 
ATOM   92   C CG  . TYR   A 1 31  ? -15.733 -17.141 0.826   1.00 46.19  ? 404 TYR   A CG  1 
ATOM   93   C CD1 . TYR   A 1 31  ? -14.404 -17.492 0.644   1.00 50.17  ? 404 TYR   A CD1 1 
ATOM   94   C CD2 . TYR   A 1 31  ? -16.333 -16.374 -0.148  1.00 43.87  ? 404 TYR   A CD2 1 
ATOM   95   C CE1 . TYR   A 1 31  ? -13.698 -17.101 -0.488  1.00 50.40  ? 404 TYR   A CE1 1 
ATOM   96   C CE2 . TYR   A 1 31  ? -15.650 -15.991 -1.289  1.00 44.93  ? 404 TYR   A CE2 1 
ATOM   97   C CZ  . TYR   A 1 31  ? -14.329 -16.357 -1.471  1.00 48.21  ? 404 TYR   A CZ  1 
ATOM   98   O OH  . TYR   A 1 31  ? -13.654 -15.976 -2.621  1.00 47.55  ? 404 TYR   A OH  1 
ATOM   99   N N   . GLY   A 1 32  ? -15.476 -14.520 3.311   1.00 53.78  ? 405 GLY   A N   1 
ATOM   100  C CA  . GLY   A 1 32  ? -15.682 -13.092 3.534   1.00 56.00  ? 405 GLY   A CA  1 
ATOM   101  C C   . GLY   A 1 32  ? -15.083 -12.218 2.431   1.00 56.90  ? 405 GLY   A C   1 
ATOM   102  O O   . GLY   A 1 32  ? -14.899 -11.030 2.636   1.00 62.48  ? 405 GLY   A O   1 
ATOM   103  N N   . GLU   A 1 33  ? -14.832 -12.783 1.245   1.00 57.54  ? 406 GLU   A N   1 
ATOM   104  C CA  . GLU   A 1 33  ? -14.136 -12.051 0.187   1.00 59.16  ? 406 GLU   A CA  1 
ATOM   105  C C   . GLU   A 1 33  ? -15.072 -11.068 -0.540  1.00 59.96  ? 406 GLU   A C   1 
ATOM   106  O O   . GLU   A 1 33  ? -14.600 -10.165 -1.225  1.00 62.77  ? 406 GLU   A O   1 
ATOM   107  C CB  . GLU   A 1 33  ? -13.522 -13.011 -0.840  1.00 62.22  ? 406 GLU   A CB  1 
ATOM   108  C CG  . GLU   A 1 33  ? -12.489 -13.973 -0.255  1.00 68.36  ? 406 GLU   A CG  1 
ATOM   109  C CD  . GLU   A 1 33  ? -11.309 -13.295 0.426   1.00 74.96  ? 406 GLU   A CD  1 
ATOM   110  O OE1 . GLU   A 1 33  ? -10.475 -12.751 -0.315  1.00 78.42  ? 406 GLU   A OE1 1 
ATOM   111  O OE2 . GLU   A 1 33  ? -11.238 -13.290 1.684   1.00 79.89  ? 406 GLU   A OE2 1 
ATOM   112  N N   . HIS   A 1 34  ? -16.392 -11.284 -0.457  1.00 55.95  ? 407 HIS   A N   1 
ATOM   113  C CA  . HIS   A 1 34  ? -17.355 -10.357 -1.023  1.00 54.81  ? 407 HIS   A CA  1 
ATOM   114  C C   . HIS   A 1 34  ? -17.581 -9.188  -0.064  1.00 59.42  ? 407 HIS   A C   1 
ATOM   115  O O   . HIS   A 1 34  ? -17.653 -9.371  1.158   1.00 59.95  ? 407 HIS   A O   1 
ATOM   116  C CB  . HIS   A 1 34  ? -18.687 -11.036 -1.337  1.00 51.91  ? 407 HIS   A CB  1 
ATOM   117  C CG  . HIS   A 1 34  ? -18.658 -12.059 -2.430  1.00 52.47  ? 407 HIS   A CG  1 
ATOM   118  N ND1 . HIS   A 1 34  ? -18.771 -11.740 -3.774  1.00 51.20  ? 407 HIS   A ND1 1 
ATOM   119  C CD2 . HIS   A 1 34  ? -18.610 -13.416 -2.369  1.00 49.93  ? 407 HIS   A CD2 1 
ATOM   120  C CE1 . HIS   A 1 34  ? -18.779 -12.861 -4.499  1.00 49.63  ? 407 HIS   A CE1 1 
ATOM   121  N NE2 . HIS   A 1 34  ? -18.676 -13.893 -3.669  1.00 51.32  ? 407 HIS   A NE2 1 
ATOM   122  N N   . HIS   A 1 35  ? -17.725 -7.988  -0.655  1.00 61.47  ? 408 HIS   A N   1 
ATOM   123  C CA  . HIS   A 1 35  ? -17.869 -6.755  0.100   1.00 66.95  ? 408 HIS   A CA  1 
ATOM   124  C C   . HIS   A 1 35  ? -19.258 -6.151  -0.124  1.00 64.27  ? 408 HIS   A C   1 
ATOM   125  O O   . HIS   A 1 35  ? -19.573 -5.107  0.438   1.00 69.73  ? 408 HIS   A O   1 
ATOM   126  C CB  . HIS   A 1 35  ? -16.707 -5.817  -0.246  1.00 70.69  ? 408 HIS   A CB  1 
ATOM   127  C CG  . HIS   A 1 35  ? -15.371 -6.422  0.064   1.00 76.49  ? 408 HIS   A CG  1 
ATOM   128  N ND1 . HIS   A 1 35  ? -15.075 -6.985  1.293   1.00 78.18  ? 408 HIS   A ND1 1 
ATOM   129  C CD2 . HIS   A 1 35  ? -14.259 -6.563  -0.689  1.00 78.88  ? 408 HIS   A CD2 1 
ATOM   130  C CE1 . HIS   A 1 35  ? -13.827 -7.440  1.277   1.00 82.65  ? 408 HIS   A CE1 1 
ATOM   131  N NE2 . HIS   A 1 35  ? -13.313 -7.194  0.083   1.00 84.65  ? 408 HIS   A NE2 1 
ATOM   132  N N   . SER   A 1 36  ? -20.077 -6.832  -0.928  1.00 58.77  ? 409 SER   A N   1 
ATOM   133  C CA  . SER   A 1 36  ? -21.449 -6.441  -1.197  1.00 58.86  ? 409 SER   A CA  1 
ATOM   134  C C   . SER   A 1 36  ? -22.375 -7.644  -1.032  1.00 58.09  ? 409 SER   A C   1 
ATOM   135  O O   . SER   A 1 36  ? -21.946 -8.791  -1.142  1.00 54.93  ? 409 SER   A O   1 
ATOM   136  C CB  . SER   A 1 36  ? -21.592 -5.883  -2.588  1.00 58.49  ? 409 SER   A CB  1 
ATOM   137  O OG  . SER   A 1 36  ? -20.834 -4.688  -2.716  1.00 67.45  ? 409 SER   A OG  1 
ATOM   138  N N   . SER   A 1 37  ? -23.669 -7.349  -0.892  1.00 55.06  ? 410 SER   A N   1 
ATOM   139  C CA  . SER   A 1 37  ? -24.684 -8.355  -0.702  1.00 52.79  ? 410 SER   A CA  1 
ATOM   140  C C   . SER   A 1 37  ? -24.588 -9.441  -1.775  1.00 50.12  ? 410 SER   A C   1 
ATOM   141  O O   . SER   A 1 37  ? -24.395 -9.157  -2.968  1.00 48.97  ? 410 SER   A O   1 
ATOM   142  C CB  . SER   A 1 37  ? -26.043 -7.761  -0.686  1.00 50.81  ? 410 SER   A CB  1 
ATOM   143  O OG  . SER   A 1 37  ? -26.995 -8.775  -0.417  1.00 51.74  ? 410 SER   A OG  1 
ATOM   144  N N   . ILE   A 1 38  ? -24.806 -10.683 -1.326  1.00 45.79  ? 411 ILE   A N   1 
ATOM   145  C CA  . ILE   A 1 38  ? -24.684 -11.850 -2.179  1.00 42.61  ? 411 ILE   A CA  1 
ATOM   146  C C   . ILE   A 1 38  ? -25.966 -12.007 -2.987  1.00 40.20  ? 411 ILE   A C   1 
ATOM   147  O O   . ILE   A 1 38  ? -27.067 -11.908 -2.460  1.00 39.76  ? 411 ILE   A O   1 
ATOM   148  C CB  . ILE   A 1 38  ? -24.382 -13.099 -1.337  1.00 40.74  ? 411 ILE   A CB  1 
ATOM   149  C CG1 . ILE   A 1 38  ? -23.068 -12.960 -0.566  1.00 44.27  ? 411 ILE   A CG1 1 
ATOM   150  C CG2 . ILE   A 1 38  ? -24.400 -14.341 -2.203  1.00 38.31  ? 411 ILE   A CG2 1 
ATOM   151  C CD1 . ILE   A 1 38  ? -21.889 -12.541 -1.424  1.00 45.82  ? 411 ILE   A CD1 1 
ATOM   152  N N   . MET   A 1 39  ? -25.820 -12.317 -4.269  1.00 42.03  ? 412 MET   A N   1 
ATOM   153  C CA  . MET   A 1 39  ? -26.978 -12.557 -5.103  1.00 42.99  ? 412 MET   A CA  1 
ATOM   154  C C   . MET   A 1 39  ? -27.240 -14.060 -5.211  1.00 40.21  ? 412 MET   A C   1 
ATOM   155  O O   . MET   A 1 39  ? -28.374 -14.479 -5.071  1.00 41.74  ? 412 MET   A O   1 
ATOM   156  C CB  . MET   A 1 39  ? -26.781 -11.953 -6.491  1.00 43.44  ? 412 MET   A CB  1 
ATOM   157  C CG  . MET   A 1 39  ? -28.028 -12.033 -7.352  1.00 49.57  ? 412 MET   A CG  1 
ATOM   158  S SD  . MET   A 1 39  ? -27.878 -11.173 -8.936  1.00 53.84  ? 412 MET   A SD  1 
ATOM   159  C CE  . MET   A 1 39  ? -27.071 -9.677  -8.366  1.00 44.16  ? 412 MET   A CE  1 
ATOM   160  N N   . HIS   A 1 40  ? -26.205 -14.831 -5.579  1.00 40.83  ? 413 HIS   A N   1 
ATOM   161  C CA  . HIS   A 1 40  ? -26.285 -16.280 -5.708  1.00 40.47  ? 413 HIS   A CA  1 
ATOM   162  C C   . HIS   A 1 40  ? -25.034 -16.903 -5.096  1.00 41.21  ? 413 HIS   A C   1 
ATOM   163  O O   . HIS   A 1 40  ? -23.962 -16.316 -5.170  1.00 45.43  ? 413 HIS   A O   1 
ATOM   164  C CB  . HIS   A 1 40  ? -26.366 -16.717 -7.179  1.00 42.22  ? 413 HIS   A CB  1 
ATOM   165  C CG  . HIS   A 1 40  ? -27.522 -16.174 -7.943  1.00 41.22  ? 413 HIS   A CG  1 
ATOM   166  N ND1 . HIS   A 1 40  ? -28.787 -16.694 -7.855  1.00 37.12  ? 413 HIS   A ND1 1 
ATOM   167  C CD2 . HIS   A 1 40  ? -27.605 -15.146 -8.830  1.00 45.18  ? 413 HIS   A CD2 1 
ATOM   168  C CE1 . HIS   A 1 40  ? -29.607 -15.998 -8.626  1.00 39.10  ? 413 HIS   A CE1 1 
ATOM   169  N NE2 . HIS   A 1 40  ? -28.913 -15.055 -9.240  1.00 39.92  ? 413 HIS   A NE2 1 
ATOM   170  N N   . CYS   A 1 41  ? -25.176 -18.107 -4.505  1.00 42.00  ? 414 CYS   A N   1 
ATOM   171  C CA  . CYS   A 1 41  ? -24.033 -18.957 -4.199  1.00 38.10  ? 414 CYS   A CA  1 
ATOM   172  C C   . CYS   A 1 41  ? -24.423 -20.409 -4.413  1.00 37.08  ? 414 CYS   A C   1 
ATOM   173  O O   . CYS   A 1 41  ? -25.363 -20.887 -3.797  1.00 35.41  ? 414 CYS   A O   1 
ATOM   174  C CB  . CYS   A 1 41  ? -23.514 -18.761 -2.777  1.00 41.23  ? 414 CYS   A CB  1 
ATOM   175  S SG  . CYS   A 1 41  ? -24.787 -18.844 -1.481  1.00 45.24  ? 414 CYS   A SG  1 
ATOM   176  N N   . ARG   A 1 42  ? -23.647 -21.123 -5.236  1.00 37.52  ? 415 ARG   A N   1 
ATOM   177  C CA  . ARG   A 1 42  ? -24.007 -22.487 -5.628  1.00 37.53  ? 415 ARG   A CA  1 
ATOM   178  C C   . ARG   A 1 42  ? -22.774 -23.389 -5.641  1.00 36.57  ? 415 ARG   A C   1 
ATOM   179  O O   . ARG   A 1 42  ? -21.719 -23.013 -6.148  1.00 37.29  ? 415 ARG   A O   1 
ATOM   180  C CB  . ARG   A 1 42  ? -24.627 -22.450 -7.037  1.00 41.14  ? 415 ARG   A CB  1 
ATOM   181  C CG  . ARG   A 1 42  ? -25.968 -21.735 -7.160  1.00 37.54  ? 415 ARG   A CG  1 
ATOM   182  C CD  . ARG   A 1 42  ? -27.067 -22.390 -6.272  1.00 39.97  ? 415 ARG   A CD  1 
ATOM   183  N NE  . ARG   A 1 42  ? -27.167 -23.854 -6.447  1.00 41.03  ? 415 ARG   A NE  1 
ATOM   184  C CZ  . ARG   A 1 42  ? -27.867 -24.469 -7.423  1.00 43.51  ? 415 ARG   A CZ  1 
ATOM   185  N NH1 . ARG   A 1 42  ? -28.577 -23.752 -8.259  1.00 37.38  ? 415 ARG   A NH1 1 
ATOM   186  N NH2 . ARG   A 1 42  ? -27.802 -25.788 -7.594  1.00 41.55  ? 415 ARG   A NH2 1 
ATOM   187  N N   . VAL   A 1 43  ? -22.915 -24.583 -5.064  1.00 35.81  ? 416 VAL   A N   1 
ATOM   188  C CA  . VAL   A 1 43  ? -21.876 -25.595 -5.125  1.00 37.32  ? 416 VAL   A CA  1 
ATOM   189  C C   . VAL   A 1 43  ? -21.915 -26.235 -6.503  1.00 34.86  ? 416 VAL   A C   1 
ATOM   190  O O   . VAL   A 1 43  ? -22.974 -26.373 -7.068  1.00 37.53  ? 416 VAL   A O   1 
ATOM   191  C CB  . VAL   A 1 43  ? -22.110 -26.618 -4.000  1.00 41.27  ? 416 VAL   A CB  1 
ATOM   192  C CG1 . VAL   A 1 43  ? -21.007 -27.676 -3.954  1.00 43.45  ? 416 VAL   A CG1 1 
ATOM   193  C CG2 . VAL   A 1 43  ? -22.268 -25.912 -2.649  1.00 41.63  ? 416 VAL   A CG2 1 
ATOM   194  N N   . ASP   A 1 44  ? -20.745 -26.512 -7.072  1.00 40.90  ? 417 ASP   A N   1 
ATOM   195  C CA  . ASP   A 1 44  ? -20.630 -27.169 -8.371  1.00 43.65  ? 417 ASP   A CA  1 
ATOM   196  C C   . ASP   A 1 44  ? -21.028 -28.638 -8.223  1.00 46.69  ? 417 ASP   A C   1 
ATOM   197  O O   . ASP   A 1 44  ? -21.254 -29.103 -7.113  1.00 47.44  ? 417 ASP   A O   1 
ATOM   198  C CB  . ASP   A 1 44  ? -19.206 -27.094 -8.894  1.00 43.25  ? 417 ASP   A CB  1 
ATOM   199  C CG  . ASP   A 1 44  ? -18.241 -28.064 -8.221  1.00 46.03  ? 417 ASP   A CG  1 
ATOM   200  O OD1 . ASP   A 1 44  ? -18.372 -28.232 -6.993  1.00 43.72  ? 417 ASP   A OD1 1 
ATOM   201  O OD2 . ASP   A 1 44  ? -17.346 -28.623 -8.925  1.00 47.25  ? 417 ASP   A OD2 1 
ATOM   202  N N   . CYS   A 1 45  ? -21.025 -29.373 -9.337  1.00 46.84  ? 418 CYS   A N   1 
ATOM   203  C CA  . CYS   A 1 45  ? -21.569 -30.726 -9.370  1.00 50.70  ? 418 CYS   A CA  1 
ATOM   204  C C   . CYS   A 1 45  ? -20.612 -31.722 -8.713  1.00 50.29  ? 418 CYS   A C   1 
ATOM   205  O O   . CYS   A 1 45  ? -21.057 -32.760 -8.253  1.00 53.06  ? 418 CYS   A O   1 
ATOM   206  C CB  . CYS   A 1 45  ? -21.907 -31.172 -10.793 1.00 55.85  ? 418 CYS   A CB  1 
ATOM   207  S SG  . CYS   A 1 45  ? -23.393 -30.359 -11.442 1.00 64.10  ? 418 CYS   A SG  1 
ATOM   208  N N   . SER   A 1 46  ? -19.317 -31.388 -8.644  1.00 48.27  ? 419 SER   A N   1 
ATOM   209  C CA  . SER   A 1 46  ? -18.356 -32.209 -7.924  1.00 52.81  ? 419 SER   A CA  1 
ATOM   210  C C   . SER   A 1 46  ? -18.560 -32.101 -6.408  1.00 53.87  ? 419 SER   A C   1 
ATOM   211  O O   . SER   A 1 46  ? -18.076 -32.956 -5.667  1.00 61.01  ? 419 SER   A O   1 
ATOM   212  C CB  . SER   A 1 46  ? -16.911 -31.871 -8.302  1.00 54.32  ? 419 SER   A CB  1 
ATOM   213  O OG  . SER   A 1 46  ? -16.453 -30.697 -7.631  1.00 52.37  ? 419 SER   A OG  1 
ATOM   214  N N   . GLY   A 1 47  ? -19.239 -31.048 -5.944  1.00 48.71  ? 420 GLY   A N   1 
ATOM   215  C CA  . GLY   A 1 47  ? -19.456 -30.859 -4.518  1.00 48.29  ? 420 GLY   A CA  1 
ATOM   216  C C   . GLY   A 1 47  ? -18.237 -30.256 -3.806  1.00 47.79  ? 420 GLY   A C   1 
ATOM   217  O O   . GLY   A 1 47  ? -18.216 -30.198 -2.577  1.00 47.39  ? 420 GLY   A O   1 
ATOM   218  N N   . ARG   A 1 48  ? -17.280 -29.735 -4.592  1.00 48.51  ? 421 ARG   A N   1 
ATOM   219  C CA  . ARG   A 1 48  ? -15.963 -29.331 -4.111  1.00 49.91  ? 421 ARG   A CA  1 
ATOM   220  C C   . ARG   A 1 48  ? -15.667 -27.839 -4.394  1.00 50.07  ? 421 ARG   A C   1 
ATOM   221  O O   . ARG   A 1 48  ? -14.658 -27.332 -3.919  1.00 51.25  ? 421 ARG   A O   1 
ATOM   222  C CB  . ARG   A 1 48  ? -14.855 -30.208 -4.733  1.00 52.60  ? 421 ARG   A CB  1 
ATOM   223  C CG  . ARG   A 1 48  ? -14.849 -31.703 -4.382  1.00 53.62  ? 421 ARG   A CG  1 
ATOM   224  C CD  . ARG   A 1 48  ? -13.639 -32.485 -4.943  1.00 53.30  ? 421 ARG   A CD  1 
ATOM   225  N N   . ARG   A 1 49  ? -16.503 -27.123 -5.173  1.00 46.04  ? 422 ARG   A N   1 
ATOM   226  C CA  . ARG   A 1 49  ? -16.249 -25.703 -5.419  1.00 46.65  ? 422 ARG   A CA  1 
ATOM   227  C C   . ARG   A 1 49  ? -17.534 -24.902 -5.217  1.00 43.79  ? 422 ARG   A C   1 
ATOM   228  O O   . ARG   A 1 49  ? -18.618 -25.414 -5.447  1.00 44.81  ? 422 ARG   A O   1 
ATOM   229  C CB  . ARG   A 1 49  ? -15.762 -25.408 -6.847  1.00 48.82  ? 422 ARG   A CB  1 
ATOM   230  C CG  . ARG   A 1 49  ? -14.467 -26.071 -7.290  1.00 52.73  ? 422 ARG   A CG  1 
ATOM   231  C CD  . ARG   A 1 49  ? -13.227 -25.305 -6.877  1.00 57.88  ? 422 ARG   A CD  1 
ATOM   232  N NE  . ARG   A 1 49  ? -11.970 -25.981 -7.231  1.00 63.23  ? 422 ARG   A NE  1 
ATOM   233  C CZ  . ARG   A 1 49  ? -11.498 -27.090 -6.627  1.00 66.65  ? 422 ARG   A CZ  1 
ATOM   234  N NH1 . ARG   A 1 49  ? -12.218 -27.681 -5.684  1.00 65.80  ? 422 ARG   A NH1 1 
ATOM   235  N NH2 . ARG   A 1 49  ? -10.330 -27.614 -6.984  1.00 66.46  ? 422 ARG   A NH2 1 
ATOM   236  N N   . VAL   A 1 50  ? -17.398 -23.631 -4.810  1.00 43.14  ? 423 VAL   A N   1 
ATOM   237  C CA  . VAL   A 1 50  ? -18.517 -22.700 -4.809  1.00 41.65  ? 423 VAL   A CA  1 
ATOM   238  C C   . VAL   A 1 50  ? -18.303 -21.609 -5.852  1.00 41.37  ? 423 VAL   A C   1 
ATOM   239  O O   . VAL   A 1 50  ? -17.224 -21.023 -5.959  1.00 44.92  ? 423 VAL   A O   1 
ATOM   240  C CB  . VAL   A 1 50  ? -18.706 -22.058 -3.431  1.00 42.70  ? 423 VAL   A CB  1 
ATOM   241  C CG1 . VAL   A 1 50  ? -19.764 -20.958 -3.464  1.00 41.14  ? 423 VAL   A CG1 1 
ATOM   242  C CG2 . VAL   A 1 50  ? -19.050 -23.113 -2.396  1.00 45.21  ? 423 VAL   A CG2 1 
ATOM   243  N N   . ALA   A 1 51  ? -19.370 -21.265 -6.553  1.00 38.61  ? 424 ALA   A N   1 
ATOM   244  C CA  . ALA   A 1 51  ? -19.405 -20.010 -7.295  1.00 41.17  ? 424 ALA   A CA  1 
ATOM   245  C C   . ALA   A 1 51  ? -20.402 -19.058 -6.648  1.00 36.22  ? 424 ALA   A C   1 
ATOM   246  O O   . ALA   A 1 51  ? -21.562 -19.397 -6.438  1.00 35.24  ? 424 ALA   A O   1 
ATOM   247  C CB  . ALA   A 1 51  ? -19.766 -20.268 -8.739  1.00 44.30  ? 424 ALA   A CB  1 
ATOM   248  N N   . SER   A 1 52  ? -19.935 -17.866 -6.323  1.00 39.91  ? 425 SER   A N   1 
ATOM   249  C CA  . SER   A 1 52  ? -20.797 -16.883 -5.687  1.00 40.44  ? 425 SER   A CA  1 
ATOM   250  C C   . SER   A 1 52  ? -20.737 -15.548 -6.437  1.00 41.55  ? 425 SER   A C   1 
ATOM   251  O O   . SER   A 1 52  ? -19.685 -15.115 -6.925  1.00 43.10  ? 425 SER   A O   1 
ATOM   252  C CB  . SER   A 1 52  ? -20.422 -16.737 -4.240  1.00 38.67  ? 425 SER   A CB  1 
ATOM   253  O OG  . SER   A 1 52  ? -19.031 -16.503 -4.137  1.00 39.16  ? 425 SER   A OG  1 
ATOM   254  N N   . LEU   A 1 53  ? -21.879 -14.872 -6.454  1.00 42.34  ? 426 LEU   A N   1 
ATOM   255  C CA  . LEU   A 1 53  ? -22.041 -13.625 -7.175  1.00 40.51  ? 426 LEU   A CA  1 
ATOM   256  C C   . LEU   A 1 53  ? -22.710 -12.595 -6.271  1.00 40.83  ? 426 LEU   A C   1 
ATOM   257  O O   . LEU   A 1 53  ? -23.743 -12.880 -5.651  1.00 38.88  ? 426 LEU   A O   1 
ATOM   258  C CB  . LEU   A 1 53  ? -22.899 -13.928 -8.393  1.00 40.38  ? 426 LEU   A CB  1 
ATOM   259  C CG  . LEU   A 1 53  ? -23.359 -12.713 -9.205  1.00 46.23  ? 426 LEU   A CG  1 
ATOM   260  C CD1 . LEU   A 1 53  ? -22.183 -11.981 -9.802  1.00 50.61  ? 426 LEU   A CD1 1 
ATOM   261  C CD2 . LEU   A 1 53  ? -24.353 -13.114 -10.302 1.00 47.94  ? 426 LEU   A CD2 1 
ATOM   262  N N   . ASP   A 1 54  ? -22.116 -11.405 -6.192  1.00 41.85  ? 427 ASP   A N   1 
ATOM   263  C CA  . ASP   A 1 54  ? -22.678 -10.339 -5.384  1.00 46.30  ? 427 ASP   A CA  1 
ATOM   264  C C   . ASP   A 1 54  ? -23.312 -9.271  -6.296  1.00 49.95  ? 427 ASP   A C   1 
ATOM   265  O O   . ASP   A 1 54  ? -23.238 -9.367  -7.526  1.00 50.35  ? 427 ASP   A O   1 
ATOM   266  C CB  . ASP   A 1 54  ? -21.625 -9.792  -4.449  1.00 46.78  ? 427 ASP   A CB  1 
ATOM   267  C CG  . ASP   A 1 54  ? -20.499 -9.024  -5.109  1.00 49.33  ? 427 ASP   A CG  1 
ATOM   268  O OD1 . ASP   A 1 54  ? -20.781 -8.310  -6.084  1.00 52.12  ? 427 ASP   A OD1 1 
ATOM   269  O OD2 . ASP   A 1 54  ? -19.370 -9.080  -4.580  1.00 52.49  ? 427 ASP   A OD2 1 
ATOM   270  N N   . VAL   A 1 55  ? -23.900 -8.242  -5.681  1.00 47.97  ? 428 VAL   A N   1 
ATOM   271  C CA  . VAL   A 1 55  ? -24.727 -7.287  -6.407  1.00 50.22  ? 428 VAL   A CA  1 
ATOM   272  C C   . VAL   A 1 55  ? -23.858 -6.238  -7.106  1.00 53.21  ? 428 VAL   A C   1 
ATOM   273  O O   . VAL   A 1 55  ? -24.378 -5.422  -7.842  1.00 51.42  ? 428 VAL   A O   1 
ATOM   274  C CB  . VAL   A 1 55  ? -25.756 -6.582  -5.505  1.00 50.03  ? 428 VAL   A CB  1 
ATOM   275  C CG1 . VAL   A 1 55  ? -26.799 -7.559  -4.991  1.00 49.65  ? 428 VAL   A CG1 1 
ATOM   276  C CG2 . VAL   A 1 55  ? -25.101 -5.787  -4.369  1.00 50.09  ? 428 VAL   A CG2 1 
ATOM   277  N N   . ASP   A 1 56  ? -22.550 -6.253  -6.857  1.00 52.74  ? 429 ASP   A N   1 
ATOM   278  C CA  . ASP   A 1 56  ? -21.613 -5.431  -7.604  1.00 53.87  ? 429 ASP   A CA  1 
ATOM   279  C C   . ASP   A 1 56  ? -21.075 -6.176  -8.827  1.00 53.11  ? 429 ASP   A C   1 
ATOM   280  O O   . ASP   A 1 56  ? -20.084 -5.761  -9.405  1.00 58.14  ? 429 ASP   A O   1 
ATOM   281  C CB  . ASP   A 1 56  ? -20.426 -5.026  -6.745  1.00 57.39  ? 429 ASP   A CB  1 
ATOM   282  C CG  . ASP   A 1 56  ? -20.698 -3.983  -5.669  1.00 63.10  ? 429 ASP   A CG  1 
ATOM   283  O OD1 . ASP   A 1 56  ? -21.812 -3.432  -5.652  1.00 65.66  ? 429 ASP   A OD1 1 
ATOM   284  O OD2 . ASP   A 1 56  ? -19.788 -3.739  -4.838  1.00 68.68  ? 429 ASP   A OD2 1 
ATOM   285  N N   . GLY   A 1 57  ? -21.645 -7.332  -9.161  1.00 51.84  ? 430 GLY   A N   1 
ATOM   286  C CA  . GLY   A 1 57  ? -21.150 -8.135  -10.281 1.00 53.07  ? 430 GLY   A CA  1 
ATOM   287  C C   . GLY   A 1 57  ? -19.769 -8.797  -10.043 1.00 53.63  ? 430 GLY   A C   1 
ATOM   288  O O   . GLY   A 1 57  ? -19.093 -9.172  -11.013 1.00 55.34  ? 430 GLY   A O   1 
ATOM   289  N N   . VAL   A 1 58  ? -19.336 -8.943  -8.780  1.00 50.17  ? 431 VAL   A N   1 
ATOM   290  C CA  . VAL   A 1 58  ? -18.133 -9.715  -8.488  1.00 51.51  ? 431 VAL   A CA  1 
ATOM   291  C C   . VAL   A 1 58  ? -18.489 -11.201 -8.447  1.00 51.19  ? 431 VAL   A C   1 
ATOM   292  O O   . VAL   A 1 58  ? -19.362 -11.627 -7.696  1.00 46.18  ? 431 VAL   A O   1 
ATOM   293  C CB  . VAL   A 1 58  ? -17.406 -9.313  -7.198  1.00 53.52  ? 431 VAL   A CB  1 
ATOM   294  C CG1 . VAL   A 1 58  ? -16.092 -10.064 -7.075  1.00 54.97  ? 431 VAL   A CG1 1 
ATOM   295  C CG2 . VAL   A 1 58  ? -17.155 -7.800  -7.121  1.00 55.69  ? 431 VAL   A CG2 1 
ATOM   296  N N   . ILE   A 1 59  ? -17.829 -11.971 -9.307  1.00 52.23  ? 432 ILE   A N   1 
ATOM   297  C CA  . ILE   A 1 59  ? -17.931 -13.408 -9.285  1.00 51.14  ? 432 ILE   A CA  1 
ATOM   298  C C   . ILE   A 1 59  ? -16.686 -13.953 -8.593  1.00 51.22  ? 432 ILE   A C   1 
ATOM   299  O O   . ILE   A 1 59  ? -15.573 -13.495 -8.846  1.00 50.24  ? 432 ILE   A O   1 
ATOM   300  C CB  . ILE   A 1 59  ? -18.080 -13.973 -10.705 1.00 57.09  ? 432 ILE   A CB  1 
ATOM   301  C CG1 . ILE   A 1 59  ? -19.461 -13.727 -11.266 1.00 56.54  ? 432 ILE   A CG1 1 
ATOM   302  C CG2 . ILE   A 1 59  ? -17.736 -15.461 -10.720 1.00 61.20  ? 432 ILE   A CG2 1 
ATOM   303  N N   . LYS   A 1 60  ? -16.903 -14.909 -7.684  1.00 50.12  ? 433 LYS   A N   1 
ATOM   304  C CA  . LYS   A 1 60  ? -15.824 -15.599 -6.996  1.00 48.80  ? 433 LYS   A CA  1 
ATOM   305  C C   . LYS   A 1 60  ? -16.061 -17.101 -7.100  1.00 47.30  ? 433 LYS   A C   1 
ATOM   306  O O   . LYS   A 1 60  ? -17.201 -17.560 -6.989  1.00 45.98  ? 433 LYS   A O   1 
ATOM   307  C CB  . LYS   A 1 60  ? -15.732 -15.268 -5.511  1.00 49.70  ? 433 LYS   A CB  1 
ATOM   308  C CG  . LYS   A 1 60  ? -15.558 -13.823 -5.145  1.00 51.59  ? 433 LYS   A CG  1 
ATOM   309  C CD  . LYS   A 1 60  ? -14.133 -13.347 -5.215  1.00 55.15  ? 433 LYS   A CD  1 
ATOM   310  C CE  . LYS   A 1 60  ? -13.989 -11.944 -4.691  1.00 57.28  ? 433 LYS   A CE  1 
ATOM   311  N NZ  . LYS   A 1 60  ? -12.567 -11.647 -4.579  1.00 59.75  ? 433 LYS   A NZ  1 
ATOM   312  N N   . VAL   A 1 61  ? -14.964 -17.836 -7.306  1.00 48.19  ? 434 VAL   A N   1 
ATOM   313  C CA  . VAL   A 1 61  ? -14.952 -19.286 -7.301  1.00 46.70  ? 434 VAL   A CA  1 
ATOM   314  C C   . VAL   A 1 61  ? -13.916 -19.741 -6.293  1.00 47.14  ? 434 VAL   A C   1 
ATOM   315  O O   . VAL   A 1 61  ? -12.759 -19.318 -6.357  1.00 50.84  ? 434 VAL   A O   1 
ATOM   316  C CB  . VAL   A 1 61  ? -14.627 -19.826 -8.704  1.00 47.44  ? 434 VAL   A CB  1 
ATOM   317  C CG1 . VAL   A 1 61  ? -14.546 -21.347 -8.736  1.00 46.30  ? 434 VAL   A CG1 1 
ATOM   318  C CG2 . VAL   A 1 61  ? -15.623 -19.317 -9.732  1.00 45.71  ? 434 VAL   A CG2 1 
ATOM   319  N N   . TRP   A 1 62  ? -14.339 -20.628 -5.386  1.00 47.07  ? 435 TRP   A N   1 
ATOM   320  C CA  . TRP   A 1 62  ? -13.522 -21.001 -4.247  1.00 47.99  ? 435 TRP   A CA  1 
ATOM   321  C C   . TRP   A 1 62  ? -13.789 -22.439 -3.808  1.00 48.20  ? 435 TRP   A C   1 
ATOM   322  O O   . TRP   A 1 62  ? -14.890 -22.950 -3.944  1.00 46.64  ? 435 TRP   A O   1 
ATOM   323  C CB  . TRP   A 1 62  ? -13.737 -20.008 -3.096  1.00 47.40  ? 435 TRP   A CB  1 
ATOM   324  C CG  . TRP   A 1 62  ? -15.169 -19.629 -2.812  1.00 44.81  ? 435 TRP   A CG  1 
ATOM   325  C CD1 . TRP   A 1 62  ? -15.940 -18.771 -3.529  1.00 43.65  ? 435 TRP   A CD1 1 
ATOM   326  C CD2 . TRP   A 1 62  ? -15.963 -20.003 -1.664  1.00 44.46  ? 435 TRP   A CD2 1 
ATOM   327  N NE1 . TRP   A 1 62  ? -17.165 -18.624 -2.941  1.00 42.36  ? 435 TRP   A NE1 1 
ATOM   328  C CE2 . TRP   A 1 62  ? -17.205 -19.344 -1.789  1.00 41.23  ? 435 TRP   A CE2 1 
ATOM   329  C CE3 . TRP   A 1 62  ? -15.752 -20.828 -0.551  1.00 44.44  ? 435 TRP   A CE3 1 
ATOM   330  C CZ2 . TRP   A 1 62  ? -18.232 -19.499 -0.866  1.00 41.44  ? 435 TRP   A CZ2 1 
ATOM   331  C CZ3 . TRP   A 1 62  ? -16.776 -20.985 0.364   1.00 43.42  ? 435 TRP   A CZ3 1 
ATOM   332  C CH2 . TRP   A 1 62  ? -17.991 -20.315 0.217   1.00 42.13  ? 435 TRP   A CH2 1 
ATOM   333  N N   . SER   A 1 63  ? -12.734 -23.090 -3.313  1.00 53.68  ? 436 SER   A N   1 
ATOM   334  C CA  . SER   A 1 63  ? -12.852 -24.340 -2.575  1.00 52.82  ? 436 SER   A CA  1 
ATOM   335  C C   . SER   A 1 63  ? -12.938 -24.038 -1.078  1.00 55.38  ? 436 SER   A C   1 
ATOM   336  O O   . SER   A 1 63  ? -12.664 -22.910 -0.653  1.00 56.22  ? 436 SER   A O   1 
ATOM   337  C CB  . SER   A 1 63  ? -11.695 -25.234 -2.878  1.00 52.65  ? 436 SER   A CB  1 
ATOM   338  O OG  . SER   A 1 63  ? -10.480 -24.541 -2.664  1.00 52.02  ? 436 SER   A OG  1 
ATOM   339  N N   . PHE   A 1 64  ? -13.285 -25.069 -0.291  1.00 54.08  ? 437 PHE   A N   1 
ATOM   340  C CA  . PHE   A 1 64  ? -13.580 -24.904 1.124   1.00 51.18  ? 437 PHE   A CA  1 
ATOM   341  C C   . PHE   A 1 64  ? -13.131 -26.130 1.924   1.00 52.89  ? 437 PHE   A C   1 
ATOM   342  O O   . PHE   A 1 64  ? -13.104 -26.102 3.148   1.00 56.52  ? 437 PHE   A O   1 
ATOM   343  C CB  . PHE   A 1 64  ? -15.076 -24.656 1.267   1.00 47.16  ? 437 PHE   A CB  1 
ATOM   344  C CG  . PHE   A 1 64  ? -15.939 -25.666 0.529   1.00 47.32  ? 437 PHE   A CG  1 
ATOM   345  C CD1 . PHE   A 1 64  ? -16.309 -26.868 1.128   1.00 50.78  ? 437 PHE   A CD1 1 
ATOM   346  C CD2 . PHE   A 1 64  ? -16.373 -25.415 -0.768  1.00 47.37  ? 437 PHE   A CD2 1 
ATOM   347  C CE1 . PHE   A 1 64  ? -17.095 -27.783 0.444   1.00 51.87  ? 437 PHE   A CE1 1 
ATOM   348  C CE2 . PHE   A 1 64  ? -17.173 -26.323 -1.448  1.00 47.11  ? 437 PHE   A CE2 1 
ATOM   349  C CZ  . PHE   A 1 64  ? -17.527 -27.509 -0.849  1.00 49.13  ? 437 PHE   A CZ  1 
ATOM   350  N N   . ASN   A 1 65  ? -12.749 -27.200 1.236   1.00 51.02  ? 438 ASN   A N   1 
ATOM   351  C CA  . ASN   A 1 65  ? -12.365 -28.421 1.920   1.00 52.01  ? 438 ASN   A CA  1 
ATOM   352  C C   . ASN   A 1 65  ? -10.958 -28.778 1.481   1.00 55.16  ? 438 ASN   A C   1 
ATOM   353  O O   . ASN   A 1 65  ? -10.778 -29.111 0.310   1.00 55.51  ? 438 ASN   A O   1 
ATOM   354  C CB  . ASN   A 1 65  ? -13.356 -29.545 1.645   1.00 49.71  ? 438 ASN   A CB  1 
ATOM   355  C CG  . ASN   A 1 65  ? -13.019 -30.809 2.393   1.00 53.53  ? 438 ASN   A CG  1 
ATOM   356  O OD1 . ASN   A 1 65  ? -12.322 -30.791 3.430   1.00 54.05  ? 438 ASN   A OD1 1 
ATOM   357  N ND2 . ASN   A 1 65  ? -13.492 -31.929 1.871   1.00 53.59  ? 438 ASN   A ND2 1 
ATOM   358  N N   . PRO   A 1 66  ? -9.922  -28.717 2.373   1.00 56.73  ? 439 PRO   A N   1 
ATOM   359  C CA  . PRO   A 1 66  ? -10.100 -28.501 3.818   1.00 58.02  ? 439 PRO   A CA  1 
ATOM   360  C C   . PRO   A 1 66  ? -10.162 -27.056 4.331   1.00 60.21  ? 439 PRO   A C   1 
ATOM   361  O O   . PRO   A 1 66  ? -10.567 -26.815 5.478   1.00 60.93  ? 439 PRO   A O   1 
ATOM   362  C CB  . PRO   A 1 66  ? -8.857  -29.194 4.338   1.00 61.07  ? 439 PRO   A CB  1 
ATOM   363  C CG  . PRO   A 1 66  ? -7.786  -28.843 3.327   1.00 61.79  ? 439 PRO   A CG  1 
ATOM   364  C CD  . PRO   A 1 66  ? -8.508  -28.848 1.999   1.00 58.80  ? 439 PRO   A CD  1 
ATOM   365  N N   . ILE   A 1 67  ? -9.679  -26.106 3.520   1.00 59.45  ? 440 ILE   A N   1 
ATOM   366  C CA  . ILE   A 1 67  ? -9.846  -24.696 3.843   1.00 59.60  ? 440 ILE   A CA  1 
ATOM   367  C C   . ILE   A 1 67  ? -10.451 -23.945 2.651   1.00 56.55  ? 440 ILE   A C   1 
ATOM   368  O O   . ILE   A 1 67  ? -10.454 -24.403 1.504   1.00 54.03  ? 440 ILE   A O   1 
ATOM   369  C CB  . ILE   A 1 67  ? -8.528  -24.042 4.300   1.00 60.22  ? 440 ILE   A CB  1 
ATOM   370  C CG1 . ILE   A 1 67  ? -7.419  -24.187 3.255   1.00 61.03  ? 440 ILE   A CG1 1 
ATOM   371  C CG2 . ILE   A 1 67  ? -8.097  -24.577 5.661   1.00 63.64  ? 440 ILE   A CG2 1 
ATOM   372  C CD1 . ILE   A 1 67  ? -6.193  -23.324 3.530   1.00 62.61  ? 440 ILE   A CD1 1 
ATOM   373  N N   . MET   A 1 68  ? -10.913 -22.750 2.966   1.00 56.80  ? 441 MET   A N   1 
ATOM   374  C CA  . MET   A 1 68  ? -11.369 -21.801 1.978   1.00 56.93  ? 441 MET   A CA  1 
ATOM   375  C C   . MET   A 1 68  ? -10.186 -21.225 1.233   1.00 57.05  ? 441 MET   A C   1 
ATOM   376  O O   . MET   A 1 68  ? -9.284  -20.701 1.847   1.00 60.38  ? 441 MET   A O   1 
ATOM   377  C CB  . MET   A 1 68  ? -12.160 -20.707 2.679   1.00 56.59  ? 441 MET   A CB  1 
ATOM   378  C CG  . MET   A 1 68  ? -13.580 -21.116 2.808   1.00 57.22  ? 441 MET   A CG  1 
ATOM   379  S SD  . MET   A 1 68  ? -14.437 -20.266 4.130   1.00 64.60  ? 441 MET   A SD  1 
ATOM   380  C CE  . MET   A 1 68  ? -15.999 -21.135 3.939   1.00 58.49  ? 441 MET   A CE  1 
ATOM   381  N N   . GLN   A 1 69  ? -10.168 -21.381 -0.087  1.00 57.45  ? 442 GLN   A N   1 
ATOM   382  C CA  . GLN   A 1 69  ? -9.292  -20.554 -0.893  1.00 61.59  ? 442 GLN   A CA  1 
ATOM   383  C C   . GLN   A 1 69  ? -9.966  -20.197 -2.223  1.00 58.64  ? 442 GLN   A C   1 
ATOM   384  O O   . GLN   A 1 69  ? -10.792 -20.953 -2.761  1.00 55.62  ? 442 GLN   A O   1 
ATOM   385  C CB  . GLN   A 1 69  ? -7.909  -21.188 -0.978  1.00 68.37  ? 442 GLN   A CB  1 
ATOM   386  C CG  . GLN   A 1 69  ? -7.765  -22.245 -2.055  1.00 72.01  ? 442 GLN   A CG  1 
ATOM   387  C CD  . GLN   A 1 69  ? -6.504  -23.066 -1.894  1.00 82.20  ? 442 GLN   A CD  1 
ATOM   388  O OE1 . GLN   A 1 69  ? -6.321  -24.097 -2.555  1.00 87.57  ? 442 GLN   A OE1 1 
ATOM   389  N NE2 . GLN   A 1 69  ? -5.634  -22.638 -0.985  1.00 85.01  ? 442 GLN   A NE2 1 
ATOM   390  N N   . THR   A 1 70  ? -9.649  -18.980 -2.682  1.00 57.16  ? 443 THR   A N   1 
ATOM   391  C CA  . THR   A 1 70  ? -10.221 -18.388 -3.879  1.00 56.70  ? 443 THR   A CA  1 
ATOM   392  C C   . THR   A 1 70  ? -9.451  -18.880 -5.096  1.00 58.08  ? 443 THR   A C   1 
ATOM   393  O O   . THR   A 1 70  ? -8.242  -18.795 -5.115  1.00 65.36  ? 443 THR   A O   1 
ATOM   394  C CB  . THR   A 1 70  ? -10.146 -16.865 -3.733  1.00 56.17  ? 443 THR   A CB  1 
ATOM   395  O OG1 . THR   A 1 70  ? -10.793 -16.609 -2.492  1.00 54.92  ? 443 THR   A OG1 1 
ATOM   396  C CG2 . THR   A 1 70  ? -10.821 -16.117 -4.874  1.00 55.92  ? 443 THR   A CG2 1 
ATOM   397  N N   . LYS   A 1 71  ? -10.155 -19.393 -6.103  1.00 60.59  ? 444 LYS   A N   1 
ATOM   398  C CA  . LYS   A 1 71  ? -9.506  -19.914 -7.306  1.00 63.73  ? 444 LYS   A CA  1 
ATOM   399  C C   . LYS   A 1 71  ? -9.624  -18.916 -8.463  1.00 64.23  ? 444 LYS   A C   1 
ATOM   400  O O   . LYS   A 1 71  ? -8.742  -18.848 -9.309  1.00 68.72  ? 444 LYS   A O   1 
ATOM   401  C CB  . LYS   A 1 71  ? -10.123 -21.251 -7.732  1.00 64.22  ? 444 LYS   A CB  1 
ATOM   402  C CG  . LYS   A 1 71  ? -9.976  -22.401 -6.731  1.00 69.35  ? 444 LYS   A CG  1 
ATOM   403  C CD  . LYS   A 1 71  ? -8.570  -22.991 -6.604  1.00 73.70  ? 444 LYS   A CD  1 
ATOM   404  C CE  . LYS   A 1 71  ? -8.546  -24.127 -5.623  1.00 74.68  ? 444 LYS   A CE  1 
ATOM   405  N NZ  . LYS   A 1 71  ? -7.222  -24.735 -5.479  1.00 77.78  ? 444 LYS   A NZ  1 
ATOM   406  N N   . ALA   A 1 72  ? -10.732 -18.162 -8.513  1.00 61.19  ? 445 ALA   A N   1 
ATOM   407  C CA  . ALA   A 1 72  ? -10.913 -17.141 -9.537  1.00 63.83  ? 445 ALA   A CA  1 
ATOM   408  C C   . ALA   A 1 72  ? -11.693 -15.946 -8.976  1.00 64.53  ? 445 ALA   A C   1 
ATOM   409  O O   . ALA   A 1 72  ? -12.609 -16.100 -8.169  1.00 60.00  ? 445 ALA   A O   1 
ATOM   410  C CB  . ALA   A 1 72  ? -11.600 -17.745 -10.759 1.00 61.10  ? 445 ALA   A CB  1 
ATOM   411  N N   . SER   A 1 73  ? -11.308 -14.743 -9.406  1.00 67.97  ? 446 SER   A N   1 
ATOM   412  C CA  . SER   A 1 73  ? -12.056 -13.541 -9.072  1.00 69.12  ? 446 SER   A CA  1 
ATOM   413  C C   . SER   A 1 73  ? -12.126 -12.632 -10.295 1.00 71.93  ? 446 SER   A C   1 
ATOM   414  O O   . SER   A 1 73  ? -11.115 -12.393 -10.936 1.00 76.93  ? 446 SER   A O   1 
ATOM   415  C CB  . SER   A 1 73  ? -11.436 -12.841 -7.902  1.00 66.68  ? 446 SER   A CB  1 
ATOM   416  O OG  . SER   A 1 73  ? -12.405 -12.047 -7.241  1.00 64.48  ? 446 SER   A OG  1 
ATOM   417  N N   . SER   A 1 74  ? -13.332 -12.181 -10.652 1.00 76.26  ? 447 SER   A N   1 
ATOM   418  C CA  . SER   A 1 74  ? -13.479 -11.203 -11.722 1.00 78.26  ? 447 SER   A CA  1 
ATOM   419  C C   . SER   A 1 74  ? -14.620 -10.238 -11.405 1.00 75.83  ? 447 SER   A C   1 
ATOM   420  O O   . SER   A 1 74  ? -15.590 -10.613 -10.735 1.00 66.89  ? 447 SER   A O   1 
ATOM   421  C CB  . SER   A 1 74  ? -13.652 -11.865 -13.090 1.00 79.82  ? 447 SER   A CB  1 
ATOM   422  O OG  . SER   A 1 74  ? -14.798 -12.702 -13.154 1.00 81.33  ? 447 SER   A OG  1 
ATOM   423  N N   . ILE   A 1 75  ? -14.434 -8.975  -11.844 1.00 77.94  ? 448 ILE   A N   1 
ATOM   424  C CA  . ILE   A 1 75  ? -15.472 -7.948  -11.839 1.00 76.78  ? 448 ILE   A CA  1 
ATOM   425  C C   . ILE   A 1 75  ? -16.136 -7.955  -13.215 1.00 72.69  ? 448 ILE   A C   1 
ATOM   426  O O   . ILE   A 1 75  ? -15.469 -7.804  -14.241 1.00 74.85  ? 448 ILE   A O   1 
ATOM   427  C CB  . ILE   A 1 75  ? -14.904 -6.543  -11.509 1.00 83.05  ? 448 ILE   A CB  1 
ATOM   428  C CG1 . ILE   A 1 75  ? -13.616 -6.604  -10.649 1.00 86.97  ? 448 ILE   A CG1 1 
ATOM   429  C CG2 . ILE   A 1 75  ? -15.969 -5.648  -10.863 1.00 80.02  ? 448 ILE   A CG2 1 
ATOM   430  N N   . SER   A 1 76  ? -17.456 -8.096  -13.234 1.00 65.02  ? 449 SER   A N   1 
ATOM   431  C CA  . SER   A 1 76  ? -18.196 -7.952  -14.470 1.00 67.73  ? 449 SER   A CA  1 
ATOM   432  C C   . SER   A 1 76  ? -18.467 -6.471  -14.754 1.00 74.02  ? 449 SER   A C   1 
ATOM   433  O O   . SER   A 1 76  ? -18.954 -5.755  -13.879 1.00 75.72  ? 449 SER   A O   1 
ATOM   434  C CB  . SER   A 1 76  ? -19.460 -8.728  -14.407 1.00 64.11  ? 449 SER   A CB  1 
ATOM   435  O OG  . SER   A 1 76  ? -20.027 -8.830  -15.701 1.00 65.48  ? 449 SER   A OG  1 
ATOM   436  N N   . LYS   A 1 77  ? -18.160 -6.020  -15.981 1.00 76.27  ? 450 LYS   A N   1 
ATOM   437  C CA  . LYS   A 1 77  ? -18.491 -4.662  -16.398 1.00 86.06  ? 450 LYS   A CA  1 
ATOM   438  C C   . LYS   A 1 77  ? -20.015 -4.545  -16.533 1.00 86.69  ? 450 LYS   A C   1 
ATOM   439  O O   . LYS   A 1 77  ? -20.617 -3.558  -16.106 1.00 88.19  ? 450 LYS   A O   1 
ATOM   440  C CB  . LYS   A 1 77  ? -17.743 -4.274  -17.686 1.00 88.12  ? 450 LYS   A CB  1 
ATOM   441  N N   . SER   A 1 78  ? -20.634 -5.595  -17.084 1.00 81.13  ? 451 SER   A N   1 
ATOM   442  C CA  . SER   A 1 78  ? -22.074 -5.638  -17.258 1.00 76.51  ? 451 SER   A CA  1 
ATOM   443  C C   . SER   A 1 78  ? -22.738 -6.282  -16.044 1.00 72.86  ? 451 SER   A C   1 
ATOM   444  O O   . SER   A 1 78  ? -22.165 -7.137  -15.384 1.00 65.84  ? 451 SER   A O   1 
ATOM   445  C CB  . SER   A 1 78  ? -22.426 -6.377  -18.503 1.00 77.12  ? 451 SER   A CB  1 
ATOM   446  O OG  . SER   A 1 78  ? -21.670 -5.884  -19.594 1.00 90.14  ? 451 SER   A OG  1 
ATOM   447  N N   . PRO   A 1 79  ? -23.993 -5.914  -15.730 1.00 71.35  ? 452 PRO   A N   1 
ATOM   448  C CA  . PRO   A 1 79  ? -24.725 -6.588  -14.663 1.00 61.66  ? 452 PRO   A CA  1 
ATOM   449  C C   . PRO   A 1 79  ? -24.873 -8.086  -14.914 1.00 59.02  ? 452 PRO   A C   1 
ATOM   450  O O   . PRO   A 1 79  ? -25.138 -8.512  -16.044 1.00 56.78  ? 452 PRO   A O   1 
ATOM   451  C CB  . PRO   A 1 79  ? -26.084 -5.864  -14.623 1.00 63.29  ? 452 PRO   A CB  1 
ATOM   452  C CG  . PRO   A 1 79  ? -26.171 -5.132  -15.959 1.00 70.15  ? 452 PRO   A CG  1 
ATOM   453  C CD  . PRO   A 1 79  ? -24.735 -4.796  -16.343 1.00 72.03  ? 452 PRO   A CD  1 
ATOM   454  N N   . LEU   A 1 80  ? -24.729 -8.867  -13.828 1.00 55.93  ? 453 LEU   A N   1 
ATOM   455  C CA  . LEU   A 1 80  ? -24.934 -10.314 -13.839 1.00 48.56  ? 453 LEU   A CA  1 
ATOM   456  C C   . LEU   A 1 80  ? -26.104 -10.648 -12.939 1.00 45.17  ? 453 LEU   A C   1 
ATOM   457  O O   . LEU   A 1 80  ? -26.188 -10.161 -11.819 1.00 45.94  ? 453 LEU   A O   1 
ATOM   458  C CB  . LEU   A 1 80  ? -23.682 -11.027 -13.355 1.00 49.57  ? 453 LEU   A CB  1 
ATOM   459  C CG  . LEU   A 1 80  ? -22.490 -11.012 -14.315 1.00 52.11  ? 453 LEU   A CG  1 
ATOM   460  C CD1 . LEU   A 1 80  ? -21.340 -11.891 -13.806 1.00 50.91  ? 453 LEU   A CD1 1 
ATOM   461  C CD2 . LEU   A 1 80  ? -22.929 -11.444 -15.700 1.00 52.69  ? 453 LEU   A CD2 1 
ATOM   462  N N   . LEU   A 1 81  ? -27.018 -11.467 -13.447 1.00 43.87  ? 454 LEU   A N   1 
ATOM   463  C CA  . LEU   A 1 81  ? -28.254 -11.730 -12.737 1.00 42.30  ? 454 LEU   A CA  1 
ATOM   464  C C   . LEU   A 1 81  ? -28.371 -13.199 -12.329 1.00 39.24  ? 454 LEU   A C   1 
ATOM   465  O O   . LEU   A 1 81  ? -29.256 -13.529 -11.542 1.00 39.71  ? 454 LEU   A O   1 
ATOM   466  C CB  . LEU   A 1 81  ? -29.418 -11.332 -13.626 1.00 41.40  ? 454 LEU   A CB  1 
ATOM   467  C CG  . LEU   A 1 81  ? -29.490 -9.862  -14.034 1.00 47.28  ? 454 LEU   A CG  1 
ATOM   468  C CD1 . LEU   A 1 81  ? -30.808 -9.651  -14.755 1.00 48.47  ? 454 LEU   A CD1 1 
ATOM   469  C CD2 . LEU   A 1 81  ? -29.360 -8.908  -12.859 1.00 48.76  ? 454 LEU   A CD2 1 
ATOM   470  N N   . SER   A 1 82  ? -27.583 -14.093 -12.958 1.00 37.21  ? 455 SER   A N   1 
ATOM   471  C CA  . SER   A 1 82  ? -27.842 -15.525 -12.814 1.00 36.54  ? 455 SER   A CA  1 
ATOM   472  C C   . SER   A 1 82  ? -26.584 -16.330 -13.057 1.00 34.88  ? 455 SER   A C   1 
ATOM   473  O O   . SER   A 1 82  ? -25.676 -15.887 -13.745 1.00 38.18  ? 455 SER   A O   1 
ATOM   474  C CB  . SER   A 1 82  ? -28.960 -15.995 -13.698 1.00 36.26  ? 455 SER   A CB  1 
ATOM   475  O OG  . SER   A 1 82  ? -28.647 -15.794 -15.075 1.00 41.58  ? 455 SER   A OG  1 
ATOM   476  N N   . LEU   A 1 83  ? -26.581 -17.538 -12.507 1.00 34.54  ? 456 LEU   A N   1 
ATOM   477  C CA  . LEU   A 1 83  ? -25.413 -18.395 -12.488 1.00 35.76  ? 456 LEU   A CA  1 
ATOM   478  C C   . LEU   A 1 83  ? -25.842 -19.857 -12.387 1.00 33.48  ? 456 LEU   A C   1 
ATOM   479  O O   . LEU   A 1 83  ? -26.820 -20.183 -11.706 1.00 32.67  ? 456 LEU   A O   1 
ATOM   480  C CB  . LEU   A 1 83  ? -24.748 -17.820 -11.249 1.00 41.00  ? 456 LEU   A CB  1 
ATOM   481  C CG  . LEU   A 1 83  ? -23.682 -18.622 -10.524 1.00 40.16  ? 456 LEU   A CG  1 
ATOM   482  C CD1 . LEU   A 1 83  ? -23.047 -17.630 -9.565  1.00 40.15  ? 456 LEU   A CD1 1 
ATOM   483  C CD2 . LEU   A 1 83  ? -24.262 -19.800 -9.802  1.00 38.49  ? 456 LEU   A CD2 1 
ATOM   484  N N   . GLU   A 1 84  ? -25.128 -20.730 -13.106 1.00 32.33  ? 457 GLU   A N   1 
ATOM   485  C CA  . GLU   A 1 84  ? -25.460 -22.133 -13.136 1.00 32.33  ? 457 GLU   A CA  1 
ATOM   486  C C   . GLU   A 1 84  ? -24.239 -22.926 -13.569 1.00 36.02  ? 457 GLU   A C   1 
ATOM   487  O O   . GLU   A 1 84  ? -23.643 -22.633 -14.599 1.00 38.34  ? 457 GLU   A O   1 
ATOM   488  C CB  . GLU   A 1 84  ? -26.620 -22.345 -14.106 1.00 34.78  ? 457 GLU   A CB  1 
ATOM   489  C CG  . GLU   A 1 84  ? -26.909 -23.807 -14.420 1.00 34.49  ? 457 GLU   A CG  1 
ATOM   490  C CD  . GLU   A 1 84  ? -27.696 -24.543 -13.338 1.00 35.64  ? 457 GLU   A CD  1 
ATOM   491  O OE1 . GLU   A 1 84  ? -27.801 -24.051 -12.161 1.00 35.79  ? 457 GLU   A OE1 1 
ATOM   492  O OE2 . GLU   A 1 84  ? -28.188 -25.653 -13.680 1.00 33.03  ? 457 GLU   A OE2 1 
ATOM   493  N N   . TRP   A 1 85  ? -23.864 -23.912 -12.740 1.00 36.10  ? 458 TRP   A N   1 
ATOM   494  C CA  . TRP   A 1 85  ? -22.788 -24.830 -13.037 1.00 35.52  ? 458 TRP   A CA  1 
ATOM   495  C C   . TRP   A 1 85  ? -23.258 -25.814 -14.087 1.00 36.73  ? 458 TRP   A C   1 
ATOM   496  O O   . TRP   A 1 85  ? -24.401 -26.273 -14.046 1.00 38.27  ? 458 TRP   A O   1 
ATOM   497  C CB  . TRP   A 1 85  ? -22.367 -25.599 -11.781 1.00 35.99  ? 458 TRP   A CB  1 
ATOM   498  C CG  . TRP   A 1 85  ? -21.566 -24.806 -10.780 1.00 34.86  ? 458 TRP   A CG  1 
ATOM   499  C CD1 . TRP   A 1 85  ? -22.011 -24.251 -9.609  1.00 34.70  ? 458 TRP   A CD1 1 
ATOM   500  C CD2 . TRP   A 1 85  ? -20.160 -24.525 -10.849 1.00 35.85  ? 458 TRP   A CD2 1 
ATOM   501  N NE1 . TRP   A 1 85  ? -20.973 -23.652 -8.945  1.00 35.97  ? 458 TRP   A NE1 1 
ATOM   502  C CE2 . TRP   A 1 85  ? -19.830 -23.795 -9.685  1.00 36.00  ? 458 TRP   A CE2 1 
ATOM   503  C CE3 . TRP   A 1 85  ? -19.148 -24.835 -11.765 1.00 37.85  ? 458 TRP   A CE3 1 
ATOM   504  C CZ2 . TRP   A 1 85  ? -18.536 -23.376 -9.423  1.00 37.71  ? 458 TRP   A CZ2 1 
ATOM   505  C CZ3 . TRP   A 1 85  ? -17.863 -24.423 -11.497 1.00 39.15  ? 458 TRP   A CZ3 1 
ATOM   506  C CH2 . TRP   A 1 85  ? -17.560 -23.718 -10.334 1.00 39.33  ? 458 TRP   A CH2 1 
ATOM   507  N N   . ALA   A 1 86  ? -22.361 -26.124 -15.005 1.00 36.74  ? 459 ALA   A N   1 
ATOM   508  C CA  . ALA   A 1 86  ? -22.563 -27.199 -15.947 1.00 39.75  ? 459 ALA   A CA  1 
ATOM   509  C C   . ALA   A 1 86  ? -22.601 -28.526 -15.200 1.00 42.04  ? 459 ALA   A C   1 
ATOM   510  O O   . ALA   A 1 86  ? -21.872 -28.675 -14.210 1.00 43.23  ? 459 ALA   A O   1 
ATOM   511  C CB  . ALA   A 1 86  ? -21.433 -27.191 -16.940 1.00 42.22  ? 459 ALA   A CB  1 
ATOM   512  N N   . THR   A 1 87  ? -23.313 -29.516 -15.777 1.00 41.63  ? 460 THR   A N   1 
ATOM   513  C CA  . THR   A 1 87  ? -23.513 -30.814 -15.141 1.00 45.01  ? 460 THR   A CA  1 
ATOM   514  C C   . THR   A 1 87  ? -22.488 -31.844 -15.600 1.00 49.37  ? 460 THR   A C   1 
ATOM   515  O O   . THR   A 1 87  ? -22.176 -32.759 -14.852 1.00 55.13  ? 460 THR   A O   1 
ATOM   516  C CB  . THR   A 1 87  ? -24.938 -31.285 -15.409 1.00 45.15  ? 460 THR   A CB  1 
ATOM   517  O OG1 . THR   A 1 87  ? -25.136 -31.122 -16.812 1.00 42.62  ? 460 THR   A OG1 1 
ATOM   518  C CG2 . THR   A 1 87  ? -25.945 -30.496 -14.584 1.00 39.33  ? 460 THR   A CG2 1 
ATOM   519  N N   . LYS   A 1 88  ? -21.960 -31.707 -16.816 1.00 51.69  ? 461 LYS   A N   1 
ATOM   520  C CA  . LYS   A 1 88  ? -21.121 -32.758 -17.371 1.00 53.60  ? 461 LYS   A CA  1 
ATOM   521  C C   . LYS   A 1 88  ? -19.714 -32.252 -17.662 1.00 56.32  ? 461 LYS   A C   1 
ATOM   522  O O   . LYS   A 1 88  ? -18.863 -33.035 -18.065 1.00 58.98  ? 461 LYS   A O   1 
ATOM   523  C CB  . LYS   A 1 88  ? -21.692 -33.394 -18.643 1.00 56.63  ? 461 LYS   A CB  1 
ATOM   524  C CG  . LYS   A 1 88  ? -22.870 -34.341 -18.438 1.00 59.72  ? 461 LYS   A CG  1 
ATOM   525  C CD  . LYS   A 1 88  ? -22.653 -35.429 -17.390 1.00 63.39  ? 461 LYS   A CD  1 
ATOM   526  C CE  . LYS   A 1 88  ? -23.767 -36.443 -17.425 1.00 67.42  ? 461 LYS   A CE  1 
ATOM   527  N NZ  . LYS   A 1 88  ? -23.371 -37.699 -16.787 1.00 71.64  ? 461 LYS   A NZ  1 
ATOM   528  N N   . ARG   A 1 89  ? -19.463 -30.966 -17.434 1.00 57.90  ? 462 ARG   A N   1 
ATOM   529  C CA  . ARG   A 1 89  ? -18.100 -30.455 -17.394 1.00 60.84  ? 462 ARG   A CA  1 
ATOM   530  C C   . ARG   A 1 89  ? -17.968 -29.540 -16.184 1.00 56.98  ? 462 ARG   A C   1 
ATOM   531  O O   . ARG   A 1 89  ? -18.238 -28.348 -16.273 1.00 53.35  ? 462 ARG   A O   1 
ATOM   532  C CB  . ARG   A 1 89  ? -17.690 -29.636 -18.622 1.00 66.13  ? 462 ARG   A CB  1 
ATOM   533  C CG  . ARG   A 1 89  ? -17.927 -30.289 -19.970 1.00 75.96  ? 462 ARG   A CG  1 
ATOM   534  C CD  . ARG   A 1 89  ? -16.835 -31.247 -20.395 1.00 82.03  ? 462 ARG   A CD  1 
ATOM   535  N NE  . ARG   A 1 89  ? -17.120 -31.720 -21.755 1.00 89.18  ? 462 ARG   A NE  1 
ATOM   536  C CZ  . ARG   A 1 89  ? -16.899 -31.024 -22.872 1.00 97.02  ? 462 ARG   A CZ  1 
ATOM   537  N NH1 . ARG   A 1 89  ? -16.294 -29.846 -22.825 1.00 94.35  ? 462 ARG   A NH1 1 
ATOM   538  N NH2 . ARG   A 1 89  ? -17.249 -31.531 -24.042 1.00 100.59 ? 462 ARG   A NH2 1 
ATOM   539  N N   . ASP   A 1 90  ? -17.488 -30.130 -15.094 1.00 58.73  ? 463 ASP   A N   1 
ATOM   540  C CA  . ASP   A 1 90  ? -17.436 -29.551 -13.758 1.00 61.38  ? 463 ASP   A CA  1 
ATOM   541  C C   . ASP   A 1 90  ? -16.909 -28.107 -13.751 1.00 57.38  ? 463 ASP   A C   1 
ATOM   542  O O   . ASP   A 1 90  ? -17.405 -27.285 -12.998 1.00 57.09  ? 463 ASP   A O   1 
ATOM   543  C CB  . ASP   A 1 90  ? -16.592 -30.465 -12.863 1.00 66.83  ? 463 ASP   A CB  1 
ATOM   544  C CG  . ASP   A 1 90  ? -17.236 -31.799 -12.471 1.00 65.80  ? 463 ASP   A CG  1 
ATOM   545  O OD1 . ASP   A 1 90  ? -18.484 -31.922 -12.551 1.00 68.22  ? 463 ASP   A OD1 1 
ATOM   546  O OD2 . ASP   A 1 90  ? -16.501 -32.695 -12.071 1.00 70.31  ? 463 ASP   A OD2 1 
ATOM   547  N N   . ARG   A 1 91  ? -15.886 -27.828 -14.566 1.00 57.58  ? 464 ARG   A N   1 
ATOM   548  C CA  . ARG   A 1 91  ? -15.161 -26.562 -14.561 1.00 59.65  ? 464 ARG   A CA  1 
ATOM   549  C C   . ARG   A 1 91  ? -15.963 -25.404 -15.191 1.00 53.75  ? 464 ARG   A C   1 
ATOM   550  O O   . ARG   A 1 91  ? -15.591 -24.247 -15.016 1.00 51.04  ? 464 ARG   A O   1 
ATOM   551  C CB  . ARG   A 1 91  ? -13.832 -26.745 -15.313 1.00 68.86  ? 464 ARG   A CB  1 
ATOM   552  C CG  . ARG   A 1 91  ? -13.967 -27.586 -16.580 1.00 82.45  ? 464 ARG   A CG  1 
ATOM   553  C CD  . ARG   A 1 91  ? -12.931 -27.323 -17.687 1.00 91.29  ? 464 ARG   A CD  1 
ATOM   554  N NE  . ARG   A 1 91  ? -13.131 -28.307 -18.764 1.00 102.20 ? 464 ARG   A NE  1 
ATOM   555  C CZ  . ARG   A 1 91  ? -13.353 -28.062 -20.066 1.00 105.15 ? 464 ARG   A CZ  1 
ATOM   556  N NH1 . ARG   A 1 91  ? -13.912 -28.994 -20.822 1.00 104.24 ? 464 ARG   A NH1 1 
ATOM   557  N NH2 . ARG   A 1 91  ? -13.103 -26.873 -20.591 1.00 104.00 ? 464 ARG   A NH2 1 
ATOM   558  N N   . LEU   A 1 92  ? -17.062 -25.691 -15.905 1.00 47.37  ? 465 LEU   A N   1 
ATOM   559  C CA  . LEU   A 1 92  ? -17.742 -24.668 -16.682 1.00 46.97  ? 465 LEU   A CA  1 
ATOM   560  C C   . LEU   A 1 92  ? -18.894 -24.057 -15.885 1.00 44.23  ? 465 LEU   A C   1 
ATOM   561  O O   . LEU   A 1 92  ? -19.705 -24.771 -15.281 1.00 43.13  ? 465 LEU   A O   1 
ATOM   562  C CB  . LEU   A 1 92  ? -18.231 -25.212 -18.019 1.00 48.19  ? 465 LEU   A CB  1 
ATOM   563  C CG  . LEU   A 1 92  ? -17.148 -25.738 -18.962 1.00 53.11  ? 465 LEU   A CG  1 
ATOM   564  C CD1 . LEU   A 1 92  ? -17.742 -26.416 -20.199 1.00 54.72  ? 465 LEU   A CD1 1 
ATOM   565  C CD2 . LEU   A 1 92  ? -16.210 -24.608 -19.342 1.00 56.12  ? 465 LEU   A CD2 1 
ATOM   566  N N   . LEU   A 1 93  ? -18.971 -22.716 -15.938 1.00 43.22  ? 466 LEU   A N   1 
ATOM   567  C CA  . LEU   A 1 93  ? -20.034 -21.949 -15.295 1.00 41.97  ? 466 LEU   A CA  1 
ATOM   568  C C   . LEU   A 1 93  ? -20.751 -21.099 -16.345 1.00 43.51  ? 466 LEU   A C   1 
ATOM   569  O O   . LEU   A 1 93  ? -20.106 -20.370 -17.108 1.00 44.65  ? 466 LEU   A O   1 
ATOM   570  C CB  . LEU   A 1 93  ? -19.369 -21.079 -14.243 1.00 41.45  ? 466 LEU   A CB  1 
ATOM   571  C CG  . LEU   A 1 93  ? -20.276 -20.249 -13.332 1.00 41.87  ? 466 LEU   A CG  1 
ATOM   572  C CD1 . LEU   A 1 93  ? -21.191 -21.083 -12.471 1.00 41.37  ? 466 LEU   A CD1 1 
ATOM   573  C CD2 . LEU   A 1 93  ? -19.384 -19.396 -12.460 1.00 45.36  ? 466 LEU   A CD2 1 
ATOM   574  N N   . LEU   A 1 94  ? -22.076 -21.222 -16.385 1.00 38.36  ? 467 LEU   A N   1 
ATOM   575  C CA  . LEU   A 1 94  ? -22.910 -20.357 -17.197 1.00 39.72  ? 467 LEU   A CA  1 
ATOM   576  C C   . LEU   A 1 94  ? -23.268 -19.107 -16.385 1.00 42.33  ? 467 LEU   A C   1 
ATOM   577  O O   . LEU   A 1 94  ? -23.661 -19.220 -15.223 1.00 39.36  ? 467 LEU   A O   1 
ATOM   578  C CB  . LEU   A 1 94  ? -24.171 -21.105 -17.638 1.00 39.12  ? 467 LEU   A CB  1 
ATOM   579  C CG  . LEU   A 1 94  ? -23.993 -22.186 -18.706 1.00 42.44  ? 467 LEU   A CG  1 
ATOM   580  C CD1 . LEU   A 1 94  ? -25.138 -23.142 -18.666 1.00 42.75  ? 467 LEU   A CD1 1 
ATOM   581  C CD2 . LEU   A 1 94  ? -23.894 -21.566 -20.076 1.00 48.58  ? 467 LEU   A CD2 1 
ATOM   582  N N   . LEU   A 1 95  ? -23.189 -17.927 -17.044 1.00 44.18  ? 468 LEU   A N   1 
ATOM   583  C CA  . LEU   A 1 95  ? -23.516 -16.645 -16.438 1.00 41.42  ? 468 LEU   A CA  1 
ATOM   584  C C   . LEU   A 1 95  ? -24.526 -15.906 -17.311 1.00 42.88  ? 468 LEU   A C   1 
ATOM   585  O O   . LEU   A 1 95  ? -24.349 -15.796 -18.521 1.00 48.02  ? 468 LEU   A O   1 
ATOM   586  C CB  . LEU   A 1 95  ? -22.231 -15.857 -16.279 1.00 43.43  ? 468 LEU   A CB  1 
ATOM   587  C CG  . LEU   A 1 95  ? -21.203 -16.473 -15.323 1.00 45.18  ? 468 LEU   A CG  1 
ATOM   588  C CD1 . LEU   A 1 95  ? -19.934 -15.649 -15.296 1.00 46.94  ? 468 LEU   A CD1 1 
ATOM   589  C CD2 . LEU   A 1 95  ? -21.775 -16.639 -13.904 1.00 44.64  ? 468 LEU   A CD2 1 
ATOM   590  N N   . GLY   A 1 96  ? -25.620 -15.461 -16.691 1.00 41.16  ? 469 GLY   A N   1 
ATOM   591  C CA  . GLY   A 1 96  ? -26.634 -14.683 -17.386 1.00 42.29  ? 469 GLY   A CA  1 
ATOM   592  C C   . GLY   A 1 96  ? -26.591 -13.225 -16.938 1.00 41.58  ? 469 GLY   A C   1 
ATOM   593  O O   . GLY   A 1 96  ? -26.556 -12.949 -15.743 1.00 40.61  ? 469 GLY   A O   1 
ATOM   594  N N   . SER   A 1 97  ? -26.573 -12.318 -17.919 1.00 43.22  ? 470 SER   A N   1 
ATOM   595  C CA  . SER   A 1 97  ? -26.307 -10.898 -17.709 1.00 44.09  ? 470 SER   A CA  1 
ATOM   596  C C   . SER   A 1 97  ? -27.620 -10.128 -17.657 1.00 43.59  ? 470 SER   A C   1 
ATOM   597  O O   . SER   A 1 97  ? -28.688 -10.690 -17.857 1.00 41.09  ? 470 SER   A O   1 
ATOM   598  C CB  . SER   A 1 97  ? -25.433 -10.320 -18.822 1.00 45.58  ? 470 SER   A CB  1 
ATOM   599  O OG  . SER   A 1 97  ? -26.212 -10.111 -19.998 1.00 43.70  ? 470 SER   A OG  1 
ATOM   600  N N   . GLY   A 1 98  ? -27.508 -8.820  -17.435 1.00 46.54  ? 471 GLY   A N   1 
ATOM   601  C CA  . GLY   A 1 98  ? -28.654 -7.930  -17.496 1.00 47.45  ? 471 GLY   A CA  1 
ATOM   602  C C   . GLY   A 1 98  ? -28.680 -7.159  -18.817 1.00 51.63  ? 471 GLY   A C   1 
ATOM   603  O O   . GLY   A 1 98  ? -29.416 -6.193  -18.918 1.00 52.50  ? 471 GLY   A O   1 
ATOM   604  N N   . VAL   A 1 99  ? -27.868 -7.610  -19.805 1.00 50.22  ? 472 VAL   A N   1 
ATOM   605  C CA  . VAL   A 1 99  ? -27.784 -6.995  -21.122 1.00 53.04  ? 472 VAL   A CA  1 
ATOM   606  C C   . VAL   A 1 99  ? -27.917 -8.072  -22.195 1.00 52.37  ? 472 VAL   A C   1 
ATOM   607  O O   . VAL   A 1 99  ? -27.303 -7.960  -23.238 1.00 53.75  ? 472 VAL   A O   1 
ATOM   608  C CB  . VAL   A 1 99  ? -26.487 -6.187  -21.355 1.00 55.76  ? 472 VAL   A CB  1 
ATOM   609  C CG1 . VAL   A 1 99  ? -26.434 -4.932  -20.484 1.00 56.16  ? 472 VAL   A CG1 1 
ATOM   610  C CG2 . VAL   A 1 99  ? -25.227 -7.047  -21.152 1.00 54.82  ? 472 VAL   A CG2 1 
ATOM   611  N N   . GLY   A 1 100 ? -28.726 -9.102  -21.935 1.00 50.17  ? 473 GLY   A N   1 
ATOM   612  C CA  . GLY   A 1 100 ? -29.151 -10.028 -22.971 1.00 49.84  ? 473 GLY   A CA  1 
ATOM   613  C C   . GLY   A 1 100 ? -28.057 -11.007 -23.414 1.00 51.20  ? 473 GLY   A C   1 
ATOM   614  O O   . GLY   A 1 100 ? -28.062 -11.445 -24.564 1.00 52.91  ? 473 GLY   A O   1 
ATOM   615  N N   . THR   A 1 101 ? -27.158 -11.395 -22.502 1.00 49.44  ? 474 THR   A N   1 
ATOM   616  C CA  . THR   A 1 101 ? -26.039 -12.257 -22.871 1.00 50.10  ? 474 THR   A CA  1 
ATOM   617  C C   . THR   A 1 101 ? -25.961 -13.425 -21.890 1.00 49.83  ? 474 THR   A C   1 
ATOM   618  O O   . THR   A 1 101 ? -26.329 -13.292 -20.723 1.00 46.72  ? 474 THR   A O   1 
ATOM   619  C CB  . THR   A 1 101 ? -24.721 -11.473 -22.929 1.00 51.76  ? 474 THR   A CB  1 
ATOM   620  O OG1 . THR   A 1 101 ? -24.397 -11.012 -21.620 1.00 50.08  ? 474 THR   A OG1 1 
ATOM   621  C CG2 . THR   A 1 101 ? -24.781 -10.270 -23.855 1.00 51.40  ? 474 THR   A CG2 1 
ATOM   622  N N   . VAL   A 1 102 ? -25.515 -14.580 -22.412 1.00 50.97  ? 475 VAL   A N   1 
ATOM   623  C CA  . VAL   A 1 102 ? -25.148 -15.734 -21.608 1.00 49.97  ? 475 VAL   A CA  1 
ATOM   624  C C   . VAL   A 1 102 ? -23.666 -16.007 -21.848 1.00 48.79  ? 475 VAL   A C   1 
ATOM   625  O O   . VAL   A 1 102 ? -23.266 -16.218 -22.990 1.00 47.50  ? 475 VAL   A O   1 
ATOM   626  C CB  . VAL   A 1 102 ? -26.007 -16.966 -21.975 1.00 49.55  ? 475 VAL   A CB  1 
ATOM   627  C CG1 . VAL   A 1 102 ? -25.519 -18.245 -21.309 1.00 47.22  ? 475 VAL   A CG1 1 
ATOM   628  C CG2 . VAL   A 1 102 ? -27.471 -16.744 -21.653 1.00 48.61  ? 475 VAL   A CG2 1 
ATOM   629  N N   . ARG   A 1 103 ? -22.871 -16.020 -20.768 1.00 48.77  ? 476 ARG   A N   1 
ATOM   630  C CA  . ARG   A 1 103 ? -21.450 -16.316 -20.871 1.00 53.09  ? 476 ARG   A CA  1 
ATOM   631  C C   . ARG   A 1 103 ? -21.162 -17.735 -20.384 1.00 52.71  ? 476 ARG   A C   1 
ATOM   632  O O   . ARG   A 1 103 ? -21.713 -18.197 -19.371 1.00 48.37  ? 476 ARG   A O   1 
ATOM   633  C CB  . ARG   A 1 103 ? -20.541 -15.380 -20.064 1.00 57.37  ? 476 ARG   A CB  1 
ATOM   634  C CG  . ARG   A 1 103 ? -20.976 -13.929 -20.095 1.00 64.27  ? 476 ARG   A CG  1 
ATOM   635  C CD  . ARG   A 1 103 ? -19.817 -12.983 -19.997 1.00 74.25  ? 476 ARG   A CD  1 
ATOM   636  N NE  . ARG   A 1 103 ? -19.504 -12.643 -18.613 1.00 77.41  ? 476 ARG   A NE  1 
ATOM   637  C CZ  . ARG   A 1 103 ? -19.781 -11.467 -18.089 1.00 80.96  ? 476 ARG   A CZ  1 
ATOM   638  N NH1 . ARG   A 1 103 ? -19.357 -11.196 -16.866 1.00 87.51  ? 476 ARG   A NH1 1 
ATOM   639  N NH2 . ARG   A 1 103 ? -20.460 -10.567 -18.794 1.00 75.54  ? 476 ARG   A NH2 1 
ATOM   640  N N   . LEU   A 1 104 ? -20.240 -18.382 -21.103 1.00 51.18  ? 477 LEU   A N   1 
ATOM   641  C CA  . LEU   A 1 104 ? -19.643 -19.624 -20.683 1.00 49.62  ? 477 LEU   A CA  1 
ATOM   642  C C   . LEU   A 1 104 ? -18.275 -19.293 -20.118 1.00 52.77  ? 477 LEU   A C   1 
ATOM   643  O O   . LEU   A 1 104 ? -17.391 -18.823 -20.848 1.00 57.41  ? 477 LEU   A O   1 
ATOM   644  C CB  . LEU   A 1 104 ? -19.570 -20.558 -21.886 1.00 50.72  ? 477 LEU   A CB  1 
ATOM   645  C CG  . LEU   A 1 104 ? -19.135 -22.002 -21.606 1.00 51.35  ? 477 LEU   A CG  1 
ATOM   646  C CD1 . LEU   A 1 104 ? -20.081 -22.749 -20.655 1.00 48.97  ? 477 LEU   A CD1 1 
ATOM   647  C CD2 . LEU   A 1 104 ? -19.039 -22.748 -22.923 1.00 52.68  ? 477 LEU   A CD2 1 
ATOM   648  N N   . TYR   A 1 105 ? -18.125 -19.510 -18.805 1.00 51.79  ? 478 TYR   A N   1 
ATOM   649  C CA  . TYR   A 1 105 ? -16.896 -19.183 -18.101 1.00 54.05  ? 478 TYR   A CA  1 
ATOM   650  C C   . TYR   A 1 105 ? -16.201 -20.478 -17.672 1.00 52.97  ? 478 TYR   A C   1 
ATOM   651  O O   . TYR   A 1 105 ? -16.812 -21.368 -17.078 1.00 48.30  ? 478 TYR   A O   1 
ATOM   652  C CB  . TYR   A 1 105 ? -17.265 -18.250 -16.945 1.00 55.24  ? 478 TYR   A CB  1 
ATOM   653  C CG  . TYR   A 1 105 ? -16.095 -17.844 -16.061 1.00 60.34  ? 478 TYR   A CG  1 
ATOM   654  C CD1 . TYR   A 1 105 ? -15.207 -16.847 -16.454 1.00 65.78  ? 478 TYR   A CD1 1 
ATOM   655  C CD2 . TYR   A 1 105 ? -15.897 -18.430 -14.814 1.00 62.17  ? 478 TYR   A CD2 1 
ATOM   656  C CE1 . TYR   A 1 105 ? -14.153 -16.460 -15.641 1.00 65.95  ? 478 TYR   A CE1 1 
ATOM   657  C CE2 . TYR   A 1 105 ? -14.845 -18.052 -13.992 1.00 62.46  ? 478 TYR   A CE2 1 
ATOM   658  C CZ  . TYR   A 1 105 ? -13.967 -17.073 -14.413 1.00 64.08  ? 478 TYR   A CZ  1 
ATOM   659  O OH  . TYR   A 1 105 ? -12.930 -16.701 -13.624 1.00 65.79  ? 478 TYR   A OH  1 
ATOM   660  N N   . ASP   A 1 106 ? -14.904 -20.567 -17.967 1.00 57.36  ? 479 ASP   A N   1 
ATOM   661  C CA  . ASP   A 1 106 ? -14.115 -21.728 -17.601 1.00 56.87  ? 479 ASP   A CA  1 
ATOM   662  C C   . ASP   A 1 106 ? -13.327 -21.393 -16.339 1.00 56.34  ? 479 ASP   A C   1 
ATOM   663  O O   . ASP   A 1 106 ? -12.437 -20.546 -16.381 1.00 57.06  ? 479 ASP   A O   1 
ATOM   664  C CB  . ASP   A 1 106 ? -13.288 -22.200 -18.779 1.00 59.18  ? 479 ASP   A CB  1 
ATOM   665  C CG  . ASP   A 1 106 ? -12.247 -23.265 -18.474 1.00 61.59  ? 479 ASP   A CG  1 
ATOM   666  O OD1 . ASP   A 1 106 ? -11.935 -23.465 -17.284 1.00 58.82  ? 479 ASP   A OD1 1 
ATOM   667  O OD2 . ASP   A 1 106 ? -11.764 -23.879 -19.432 1.00 63.98  ? 479 ASP   A OD2 1 
ATOM   668  N N   . THR   A 1 107 ? -13.636 -22.110 -15.242 1.00 55.14  ? 480 THR   A N   1 
ATOM   669  C CA  . THR   A 1 107 ? -13.186 -21.728 -13.906 1.00 56.63  ? 480 THR   A CA  1 
ATOM   670  C C   . THR   A 1 107 ? -11.741 -22.136 -13.668 1.00 59.76  ? 480 THR   A C   1 
ATOM   671  O O   . THR   A 1 107 ? -11.109 -21.562 -12.791 1.00 62.62  ? 480 THR   A O   1 
ATOM   672  C CB  . THR   A 1 107 ? -14.094 -22.278 -12.797 1.00 54.40  ? 480 THR   A CB  1 
ATOM   673  O OG1 . THR   A 1 107 ? -14.043 -23.707 -12.793 1.00 55.37  ? 480 THR   A OG1 1 
ATOM   674  C CG2 . THR   A 1 107 ? -15.526 -21.794 -12.953 1.00 51.93  ? 480 THR   A CG2 1 
ATOM   675  N N   . GLU   A 1 108 ? -11.206 -23.094 -14.437 1.00 64.88  ? 481 GLU   A N   1 
ATOM   676  C CA  . GLU   A 1 108 ? -9.791  -23.422 -14.295 1.00 71.13  ? 481 GLU   A CA  1 
ATOM   677  C C   . GLU   A 1 108 ? -8.947  -22.481 -15.156 1.00 73.36  ? 481 GLU   A C   1 
ATOM   678  O O   . GLU   A 1 108 ? -7.909  -22.028 -14.703 1.00 80.82  ? 481 GLU   A O   1 
ATOM   679  C CB  . GLU   A 1 108 ? -9.391  -24.893 -14.469 1.00 80.20  ? 481 GLU   A CB  1 
ATOM   680  C CG  . GLU   A 1 108 ? -10.171 -25.702 -15.508 1.00 86.63  ? 481 GLU   A CG  1 
ATOM   681  C CD  . GLU   A 1 108 ? -9.484  -27.014 -15.930 1.00 94.29  ? 481 GLU   A CD  1 
ATOM   682  O OE1 . GLU   A 1 108 ? -8.345  -27.257 -15.457 1.00 93.99  ? 481 GLU   A OE1 1 
ATOM   683  O OE2 . GLU   A 1 108 ? -10.062 -27.787 -16.741 1.00 91.57  ? 481 GLU   A OE2 1 
ATOM   684  N N   . ALA   A 1 109 ? -9.395  -22.159 -16.377 1.00 73.21  ? 482 ALA   A N   1 
ATOM   685  C CA  . ALA   A 1 109 ? -8.634  -21.268 -17.253 1.00 75.45  ? 482 ALA   A CA  1 
ATOM   686  C C   . ALA   A 1 109 ? -8.790  -19.803 -16.818 1.00 74.89  ? 482 ALA   A C   1 
ATOM   687  O O   . ALA   A 1 109 ? -7.952  -18.963 -17.144 1.00 77.24  ? 482 ALA   A O   1 
ATOM   688  C CB  . ALA   A 1 109 ? -9.045  -21.466 -18.701 1.00 75.05  ? 482 ALA   A CB  1 
ATOM   689  N N   . LYS   A 1 110 ? -9.852  -19.514 -16.056 1.00 73.85  ? 483 LYS   A N   1 
ATOM   690  C CA  . LYS   A 1 110 ? -10.105 -18.181 -15.523 1.00 76.42  ? 483 LYS   A CA  1 
ATOM   691  C C   . LYS   A 1 110 ? -10.379 -17.212 -16.681 1.00 76.96  ? 483 LYS   A C   1 
ATOM   692  O O   . LYS   A 1 110 ? -9.830  -16.116 -16.721 1.00 78.44  ? 483 LYS   A O   1 
ATOM   693  C CB  . LYS   A 1 110 ? -8.958  -17.726 -14.598 1.00 78.20  ? 483 LYS   A CB  1 
ATOM   694  C CG  . LYS   A 1 110 ? -8.849  -18.433 -13.210 1.00 76.68  ? 483 LYS   A CG  1 
ATOM   695  C CD  . LYS   A 1 110 ? -7.448  -18.899 -12.775 1.00 78.83  ? 483 LYS   A CD  1 
ATOM   696  C CE  . LYS   A 1 110 ? -6.825  -18.113 -11.645 1.00 78.93  ? 483 LYS   A CE  1 
ATOM   697  N N   . LYS   A 1 111 ? -11.258 -17.617 -17.613 1.00 76.31  ? 484 LYS   A N   1 
ATOM   698  C CA  . LYS   A 1 111 ? -11.530 -16.823 -18.809 1.00 79.35  ? 484 LYS   A CA  1 
ATOM   699  C C   . LYS   A 1 111 ? -12.897 -17.187 -19.398 1.00 75.96  ? 484 LYS   A C   1 
ATOM   700  O O   . LYS   A 1 111 ? -13.342 -18.338 -19.311 1.00 65.76  ? 484 LYS   A O   1 
ATOM   701  C CB  . LYS   A 1 111 ? -10.415 -16.961 -19.862 1.00 83.54  ? 484 LYS   A CB  1 
ATOM   702  C CG  . LYS   A 1 111 ? -10.311 -18.309 -20.579 1.00 84.34  ? 484 LYS   A CG  1 
ATOM   703  N N   . ASN   A 1 112 ? -13.546 -16.174 -19.999 1.00 74.35  ? 485 ASN   A N   1 
ATOM   704  C CA  . ASN   A 1 112 ? -14.802 -16.343 -20.714 1.00 70.81  ? 485 ASN   A CA  1 
ATOM   705  C C   . ASN   A 1 112 ? -14.512 -17.029 -22.046 1.00 68.18  ? 485 ASN   A C   1 
ATOM   706  O O   . ASN   A 1 112 ? -13.746 -16.519 -22.842 1.00 72.54  ? 485 ASN   A O   1 
ATOM   707  C CB  . ASN   A 1 112 ? -15.526 -15.009 -20.923 1.00 70.53  ? 485 ASN   A CB  1 
ATOM   708  C CG  . ASN   A 1 112 ? -16.051 -14.401 -19.634 1.00 73.48  ? 485 ASN   A CG  1 
ATOM   709  O OD1 . ASN   A 1 112 ? -16.826 -15.022 -18.886 1.00 69.72  ? 485 ASN   A OD1 1 
ATOM   710  N ND2 . ASN   A 1 112 ? -15.663 -13.167 -19.363 1.00 76.15  ? 485 ASN   A ND2 1 
ATOM   711  N N   . LEU   A 1 113 ? -15.138 -18.184 -22.279 1.00 67.25  ? 486 LEU   A N   1 
ATOM   712  C CA  . LEU   A 1 113 ? -14.908 -18.953 -23.493 1.00 67.00  ? 486 LEU   A CA  1 
ATOM   713  C C   . LEU   A 1 113 ? -15.734 -18.365 -24.628 1.00 67.38  ? 486 LEU   A C   1 
ATOM   714  O O   . LEU   A 1 113 ? -15.293 -18.359 -25.770 1.00 68.95  ? 486 LEU   A O   1 
ATOM   715  C CB  . LEU   A 1 113 ? -15.254 -20.426 -23.291 1.00 66.53  ? 486 LEU   A CB  1 
ATOM   716  C CG  . LEU   A 1 113 ? -14.290 -21.236 -22.417 1.00 67.97  ? 486 LEU   A CG  1 
ATOM   717  C CD1 . LEU   A 1 113 ? -14.754 -22.694 -22.345 1.00 65.58  ? 486 LEU   A CD1 1 
ATOM   718  C CD2 . LEU   A 1 113 ? -12.862 -21.136 -22.929 1.00 70.56  ? 486 LEU   A CD2 1 
ATOM   719  N N   . CYS   A 1 114 ? -16.969 -17.953 -24.320 1.00 64.16  ? 487 CYS   A N   1 
ATOM   720  C CA  . CYS   A 1 114 ? -17.802 -17.300 -25.305 1.00 62.15  ? 487 CYS   A CA  1 
ATOM   721  C C   . CYS   A 1 114 ? -18.890 -16.495 -24.602 1.00 58.52  ? 487 CYS   A C   1 
ATOM   722  O O   . CYS   A 1 114 ? -19.120 -16.673 -23.407 1.00 54.82  ? 487 CYS   A O   1 
ATOM   723  C CB  . CYS   A 1 114 ? -18.352 -18.306 -26.311 1.00 64.35  ? 487 CYS   A CB  1 
ATOM   724  S SG  . CYS   A 1 114 ? -19.439 -19.558 -25.583 1.00 62.30  ? 487 CYS   A SG  1 
ATOM   725  N N   . GLU   A 1 115 ? -19.498 -15.571 -25.360 1.00 57.40  ? 488 GLU   A N   1 
ATOM   726  C CA  . GLU   A 1 115 ? -20.585 -14.727 -24.890 1.00 58.84  ? 488 GLU   A CA  1 
ATOM   727  C C   . GLU   A 1 115 ? -21.599 -14.568 -26.024 1.00 58.20  ? 488 GLU   A C   1 
ATOM   728  O O   . GLU   A 1 115 ? -21.266 -14.109 -27.118 1.00 59.39  ? 488 GLU   A O   1 
ATOM   729  C CB  . GLU   A 1 115 ? -20.025 -13.394 -24.398 1.00 63.50  ? 488 GLU   A CB  1 
ATOM   730  C CG  . GLU   A 1 115 ? -21.107 -12.367 -24.084 1.00 67.52  ? 488 GLU   A CG  1 
ATOM   731  C CD  . GLU   A 1 115 ? -20.824 -11.427 -22.921 1.00 68.74  ? 488 GLU   A CD  1 
ATOM   732  O OE1 . GLU   A 1 115 ? -19.691 -10.943 -22.781 1.00 71.10  ? 488 GLU   A OE1 1 
ATOM   733  O OE2 . GLU   A 1 115 ? -21.780 -11.176 -22.156 1.00 68.85  ? 488 GLU   A OE2 1 
ATOM   734  N N   . ILE   A 1 116 ? -22.812 -15.042 -25.787 1.00 56.55  ? 489 ILE   A N   1 
ATOM   735  C CA  . ILE   A 1 116 ? -23.785 -15.142 -26.850 1.00 59.12  ? 489 ILE   A CA  1 
ATOM   736  C C   . ILE   A 1 116 ? -24.931 -14.206 -26.534 1.00 58.93  ? 489 ILE   A C   1 
ATOM   737  O O   . ILE   A 1 116 ? -25.491 -14.235 -25.433 1.00 55.75  ? 489 ILE   A O   1 
ATOM   738  C CB  . ILE   A 1 116 ? -24.254 -16.590 -27.074 1.00 62.93  ? 489 ILE   A CB  1 
ATOM   739  C CG1 . ILE   A 1 116 ? -23.122 -17.454 -27.610 1.00 71.31  ? 489 ILE   A CG1 1 
ATOM   740  C CG2 . ILE   A 1 116 ? -25.451 -16.631 -28.026 1.00 66.86  ? 489 ILE   A CG2 1 
ATOM   741  C CD1 . ILE   A 1 116 ? -22.308 -18.140 -26.540 1.00 78.28  ? 489 ILE   A CD1 1 
ATOM   742  N N   . ASN   A 1 117 ? -25.249 -13.375 -27.530 1.00 62.31  ? 490 ASN   A N   1 
ATOM   743  C CA  . ASN   A 1 117 ? -26.334 -12.421 -27.465 1.00 67.76  ? 490 ASN   A CA  1 
ATOM   744  C C   . ASN   A 1 117 ? -27.650 -13.151 -27.739 1.00 72.08  ? 490 ASN   A C   1 
ATOM   745  O O   . ASN   A 1 117 ? -27.749 -13.903 -28.713 1.00 75.16  ? 490 ASN   A O   1 
ATOM   746  C CB  . ASN   A 1 117 ? -26.095 -11.277 -28.446 1.00 74.81  ? 490 ASN   A CB  1 
ATOM   747  C CG  . ASN   A 1 117 ? -26.224 -9.928  -27.782 1.00 79.28  ? 490 ASN   A CG  1 
ATOM   748  O OD1 . ASN   A 1 117 ? -27.339 -9.520  -27.421 1.00 77.18  ? 490 ASN   A OD1 1 
ATOM   749  N ND2 . ASN   A 1 117 ? -25.097 -9.241  -27.599 1.00 77.11  ? 490 ASN   A ND2 1 
ATOM   750  N N   . ILE   A 1 118 ? -28.621 -12.963 -26.828 1.00 69.50  ? 491 ILE   A N   1 
ATOM   751  C CA  . ILE   A 1 118 ? -30.028 -13.214 -27.085 1.00 74.29  ? 491 ILE   A CA  1 
ATOM   752  C C   . ILE   A 1 118 ? -30.559 -12.108 -28.002 1.00 95.67  ? 491 ILE   A C   1 
ATOM   753  O O   . ILE   A 1 118 ? -30.819 -10.981 -27.553 1.00 95.01  ? 491 ILE   A O   1 
ATOM   754  C CB  . ILE   A 1 118 ? -30.790 -13.292 -25.749 1.00 73.97  ? 491 ILE   A CB  1 
ATOM   755  C CG1 . ILE   A 1 118 ? -30.634 -14.663 -25.118 1.00 72.67  ? 491 ILE   A CG1 1 
ATOM   756  C CG2 . ILE   A 1 118 ? -32.261 -12.898 -25.878 1.00 75.22  ? 491 ILE   A CG2 1 
ATOM   757  C CD1 . ILE   A 1 118 ? -29.350 -14.830 -24.322 1.00 73.89  ? 491 ILE   A CD1 1 
ATOM   758  N N   . ASN   A 1 119 ? -30.681 -12.431 -29.301 1.00 104.39 ? 492 ASN   A N   1 
ATOM   759  C CA  . ASN   A 1 119 ? -31.126 -11.466 -30.300 1.00 115.65 ? 492 ASN   A CA  1 
ATOM   760  C C   . ASN   A 1 119 ? -32.594 -11.117 -30.028 1.00 118.47 ? 492 ASN   A C   1 
ATOM   761  O O   . ASN   A 1 119 ? -33.489 -11.630 -30.704 1.00 113.97 ? 492 ASN   A O   1 
ATOM   762  C CB  . ASN   A 1 119 ? -30.899 -11.970 -31.730 1.00 114.36 ? 492 ASN   A CB  1 
ATOM   763  C CG  . ASN   A 1 119 ? -29.433 -12.047 -32.119 1.00 116.02 ? 492 ASN   A CG  1 
ATOM   764  O OD1 . ASN   A 1 119 ? -28.627 -11.197 -31.721 1.00 121.69 ? 492 ASN   A OD1 1 
ATOM   765  N ND2 . ASN   A 1 119 ? -29.064 -13.047 -32.906 1.00 110.25 ? 492 ASN   A ND2 1 
ATOM   766  N N   . ASP   A 1 120 ? -32.816 -10.231 -29.033 1.00 113.34 ? 493 ASP   A N   1 
ATOM   767  C CA  . ASP   A 1 120 ? -34.149 -9.935  -28.525 1.00 102.31 ? 493 ASP   A CA  1 
ATOM   768  C C   . ASP   A 1 120 ? -34.155 -8.620  -27.737 1.00 96.30  ? 493 ASP   A C   1 
ATOM   769  O O   . ASP   A 1 120 ? -33.131 -7.954  -27.578 1.00 99.34  ? 493 ASP   A O   1 
ATOM   770  C CB  . ASP   A 1 120 ? -34.680 -11.092 -27.685 1.00 104.74 ? 493 ASP   A CB  1 
ATOM   771  C CG  . ASP   A 1 120 ? -35.731 -11.982 -28.340 1.00 103.27 ? 493 ASP   A CG  1 
ATOM   772  O OD1 . ASP   A 1 120 ? -36.227 -11.621 -29.437 1.00 106.37 ? 493 ASP   A OD1 1 
ATOM   773  O OD2 . ASP   A 1 120 ? -36.055 -13.024 -27.741 1.00 84.75  ? 493 ASP   A OD2 1 
ATOM   774  N N   . ASN   A 1 121 ? -35.341 -8.293  -27.215 1.00 90.13  ? 494 ASN   A N   1 
ATOM   775  C CA  . ASN   A 1 121 ? -35.606 -7.071  -26.473 1.00 89.24  ? 494 ASN   A CA  1 
ATOM   776  C C   . ASN   A 1 121 ? -35.770 -7.384  -24.982 1.00 78.43  ? 494 ASN   A C   1 
ATOM   777  O O   . ASN   A 1 121 ? -36.382 -6.609  -24.242 1.00 73.04  ? 494 ASN   A O   1 
ATOM   778  C CB  . ASN   A 1 121 ? -36.869 -6.429  -27.033 1.00 100.28 ? 494 ASN   A CB  1 
ATOM   779  C CG  . ASN   A 1 121 ? -37.909 -7.481  -27.370 1.00 104.80 ? 494 ASN   A CG  1 
ATOM   780  O OD1 . ASN   A 1 121 ? -37.739 -8.665  -27.030 1.00 99.20  ? 494 ASN   A OD1 1 
ATOM   781  N ND2 . ASN   A 1 121 ? -38.975 -7.085  -28.049 1.00 105.62 ? 494 ASN   A ND2 1 
ATOM   782  N N   . MET   A 1 122 ? -35.234 -8.542  -24.557 1.00 66.74  ? 495 MET   A N   1 
ATOM   783  C CA  . MET   A 1 122 ? -35.423 -9.048  -23.205 1.00 58.43  ? 495 MET   A CA  1 
ATOM   784  C C   . MET   A 1 122 ? -34.064 -9.245  -22.563 1.00 53.06  ? 495 MET   A C   1 
ATOM   785  O O   . MET   A 1 122 ? -33.488 -10.321 -22.671 1.00 49.21  ? 495 MET   A O   1 
ATOM   786  C CB  . MET   A 1 122 ? -36.114 -10.411 -23.221 1.00 57.19  ? 495 MET   A CB  1 
ATOM   787  C CG  . MET   A 1 122 ? -37.291 -10.500 -24.155 1.00 59.76  ? 495 MET   A CG  1 
ATOM   788  S SD  . MET   A 1 122 ? -38.843 -10.524 -23.260 1.00 59.30  ? 495 MET   A SD  1 
ATOM   789  C CE  . MET   A 1 122 ? -40.151 -10.226 -24.461 1.00 59.91  ? 495 MET   A CE  1 
ATOM   790  N N   . PRO   A 1 123 ? -33.481 -8.195  -21.957 1.00 53.62  ? 496 PRO   A N   1 
ATOM   791  C CA  . PRO   A 1 123 ? -32.103 -8.265  -21.481 1.00 52.48  ? 496 PRO   A CA  1 
ATOM   792  C C   . PRO   A 1 123 ? -31.841 -8.961  -20.152 1.00 49.34  ? 496 PRO   A C   1 
ATOM   793  O O   . PRO   A 1 123 ? -30.688 -9.106  -19.774 1.00 51.08  ? 496 PRO   A O   1 
ATOM   794  C CB  . PRO   A 1 123 ? -31.743 -6.751  -21.405 1.00 55.42  ? 496 PRO   A CB  1 
ATOM   795  C CG  . PRO   A 1 123 ? -33.041 -6.082  -21.012 1.00 55.94  ? 496 PRO   A CG  1 
ATOM   796  C CD  . PRO   A 1 123 ? -34.067 -6.844  -21.838 1.00 56.58  ? 496 PRO   A CD  1 
ATOM   797  N N   . ARG   A 1 124 ? -32.890 -9.334  -19.417 1.00 46.06  ? 497 ARG   A N   1 
ATOM   798  C CA  . ARG   A 1 124 ? -32.690 -9.829  -18.058 1.00 44.00  ? 497 ARG   A CA  1 
ATOM   799  C C   . ARG   A 1 124 ? -32.698 -11.362 -18.066 1.00 40.80  ? 497 ARG   A C   1 
ATOM   800  O O   . ARG   A 1 124 ? -33.754 -11.983 -18.109 1.00 39.24  ? 497 ARG   A O   1 
ATOM   801  C CB  . ARG   A 1 124 ? -33.713 -9.200  -17.104 1.00 43.94  ? 497 ARG   A CB  1 
ATOM   802  C CG  . ARG   A 1 124 ? -33.478 -7.701  -16.943 1.00 49.54  ? 497 ARG   A CG  1 
ATOM   803  C CD  . ARG   A 1 124 ? -34.148 -7.118  -15.697 1.00 47.40  ? 497 ARG   A CD  1 
ATOM   804  N NE  . ARG   A 1 124 ? -35.597 -7.323  -15.769 1.00 49.36  ? 497 ARG   A NE  1 
ATOM   805  C CZ  . ARG   A 1 124 ? -36.385 -7.899  -14.845 1.00 46.08  ? 497 ARG   A CZ  1 
ATOM   806  N NH1 . ARG   A 1 124 ? -35.937 -8.206  -13.650 1.00 45.65  ? 497 ARG   A NH1 1 
ATOM   807  N NH2 . ARG   A 1 124 ? -37.648 -8.100  -15.115 1.00 47.00  ? 497 ARG   A NH2 1 
ATOM   808  N N   . ILE   A 1 125 ? -31.506 -11.962 -17.979 1.00 40.46  ? 498 ILE   A N   1 
ATOM   809  C CA  . ILE   A 1 125 ? -31.384 -13.410 -17.864 1.00 39.41  ? 498 ILE   A CA  1 
ATOM   810  C C   . ILE   A 1 125 ? -31.568 -13.796 -16.396 1.00 36.99  ? 498 ILE   A C   1 
ATOM   811  O O   . ILE   A 1 125 ? -30.600 -13.935 -15.650 1.00 35.25  ? 498 ILE   A O   1 
ATOM   812  C CB  . ILE   A 1 125 ? -30.048 -13.924 -18.439 1.00 40.41  ? 498 ILE   A CB  1 
ATOM   813  C CG1 . ILE   A 1 125 ? -29.713 -13.285 -19.778 1.00 42.12  ? 498 ILE   A CG1 1 
ATOM   814  C CG2 . ILE   A 1 125 ? -30.050 -15.455 -18.549 1.00 40.98  ? 498 ILE   A CG2 1 
ATOM   815  C CD1 . ILE   A 1 125 ? -30.792 -13.465 -20.832 1.00 42.82  ? 498 ILE   A CD1 1 
ATOM   816  N N   . LEU   A 1 126 ? -32.830 -14.024 -16.020 1.00 37.83  ? 499 LEU   A N   1 
ATOM   817  C CA  . LEU   A 1 126 ? -33.212 -14.232 -14.626 1.00 37.94  ? 499 LEU   A CA  1 
ATOM   818  C C   . LEU   A 1 126 ? -32.863 -15.634 -14.137 1.00 38.04  ? 499 LEU   A C   1 
ATOM   819  O O   . LEU   A 1 126 ? -32.635 -15.804 -12.954 1.00 37.95  ? 499 LEU   A O   1 
ATOM   820  C CB  . LEU   A 1 126 ? -34.697 -13.915 -14.424 1.00 37.27  ? 499 LEU   A CB  1 
ATOM   821  C CG  . LEU   A 1 126 ? -35.072 -12.430 -14.572 1.00 40.69  ? 499 LEU   A CG  1 
ATOM   822  C CD1 . LEU   A 1 126 ? -36.565 -12.217 -14.400 1.00 41.12  ? 499 LEU   A CD1 1 
ATOM   823  C CD2 . LEU   A 1 126 ? -34.276 -11.522 -13.603 1.00 41.29  ? 499 LEU   A CD2 1 
ATOM   824  N N   . SER   A 1 127 ? -32.751 -16.624 -15.031 1.00 38.46  ? 500 SER   A N   1 
ATOM   825  C CA  . SER   A 1 127 ? -32.618 -18.011 -14.582 1.00 33.59  ? 500 SER   A CA  1 
ATOM   826  C C   . SER   A 1 127 ? -31.878 -18.837 -15.642 1.00 33.58  ? 500 SER   A C   1 
ATOM   827  O O   . SER   A 1 127 ? -32.029 -18.611 -16.839 1.00 33.40  ? 500 SER   A O   1 
ATOM   828  C CB  . SER   A 1 127 ? -33.986 -18.560 -14.305 1.00 33.83  ? 500 SER   A CB  1 
ATOM   829  O OG  . SER   A 1 127 ? -33.962 -19.781 -13.595 1.00 36.06  ? 500 SER   A OG  1 
ATOM   830  N N   . LEU   A 1 128 ? -31.008 -19.729 -15.182 1.00 32.79  ? 501 LEU   A N   1 
ATOM   831  C CA  . LEU   A 1 128 ? -30.291 -20.670 -16.027 1.00 32.11  ? 501 LEU   A CA  1 
ATOM   832  C C   . LEU   A 1 128 ? -30.424 -22.049 -15.405 1.00 34.67  ? 501 LEU   A C   1 
ATOM   833  O O   . LEU   A 1 128 ? -30.258 -22.190 -14.186 1.00 36.31  ? 501 LEU   A O   1 
ATOM   834  C CB  . LEU   A 1 128 ? -28.831 -20.286 -16.093 1.00 34.09  ? 501 LEU   A CB  1 
ATOM   835  C CG  . LEU   A 1 128 ? -28.504 -19.106 -16.987 1.00 37.78  ? 501 LEU   A CG  1 
ATOM   836  C CD1 . LEU   A 1 128 ? -27.239 -18.491 -16.569 1.00 39.90  ? 501 LEU   A CD1 1 
ATOM   837  C CD2 . LEU   A 1 128 ? -28.435 -19.558 -18.441 1.00 41.94  ? 501 LEU   A CD2 1 
ATOM   838  N N   . ALA   A 1 129 ? -30.739 -23.053 -16.233 1.00 33.85  ? 502 ALA   A N   1 
ATOM   839  C CA  . ALA   A 1 129 ? -30.725 -24.433 -15.787 1.00 33.32  ? 502 ALA   A CA  1 
ATOM   840  C C   . ALA   A 1 129 ? -30.072 -25.301 -16.845 1.00 34.60  ? 502 ALA   A C   1 
ATOM   841  O O   . ALA   A 1 129 ? -30.481 -25.312 -18.012 1.00 35.64  ? 502 ALA   A O   1 
ATOM   842  C CB  . ALA   A 1 129 ? -32.116 -24.909 -15.427 1.00 32.30  ? 502 ALA   A CB  1 
ATOM   843  N N   . CYS   A 1 130 ? -29.079 -26.068 -16.398 1.00 33.18  ? 503 CYS   A N   1 
ATOM   844  C CA  . CYS   A 1 130 ? -28.350 -26.987 -17.264 1.00 35.16  ? 503 CYS   A CA  1 
ATOM   845  C C   . CYS   A 1 130 ? -28.950 -28.388 -17.140 1.00 34.88  ? 503 CYS   A C   1 
ATOM   846  O O   . CYS   A 1 130 ? -29.185 -28.874 -16.044 1.00 36.45  ? 503 CYS   A O   1 
ATOM   847  C CB  . CYS   A 1 130 ? -26.880 -26.912 -16.902 1.00 37.30  ? 503 CYS   A CB  1 
ATOM   848  S SG  . CYS   A 1 130 ? -25.824 -27.969 -17.898 1.00 40.45  ? 503 CYS   A SG  1 
ATOM   849  N N   A SER   A 1 131 ? -29.240 -29.003 -18.279 0.50 35.87  ? 504 SER   A N   1 
ATOM   850  N N   B SER   A 1 131 ? -29.215 -29.020 -18.288 0.50 34.15  ? 504 SER   A N   1 
ATOM   851  C CA  A SER   A 1 131 ? -29.792 -30.338 -18.297 0.50 35.94  ? 504 SER   A CA  1 
ATOM   852  C CA  B SER   A 1 131 ? -29.790 -30.352 -18.325 0.50 33.10  ? 504 SER   A CA  1 
ATOM   853  C C   A SER   A 1 131 ? -28.843 -31.289 -17.580 0.50 36.07  ? 504 SER   A C   1 
ATOM   854  C C   B SER   A 1 131 ? -28.845 -31.332 -17.640 0.50 34.75  ? 504 SER   A C   1 
ATOM   855  O O   A SER   A 1 131 ? -27.619 -31.140 -17.682 0.50 36.72  ? 504 SER   A O   1 
ATOM   856  O O   B SER   A 1 131 ? -27.624 -31.254 -17.830 0.50 35.89  ? 504 SER   A O   1 
ATOM   857  C CB  A SER   A 1 131 ? -30.050 -30.799 -19.709 0.50 38.55  ? 504 SER   A CB  1 
ATOM   858  C CB  B SER   A 1 131 ? -30.115 -30.795 -19.767 0.50 33.52  ? 504 SER   A CB  1 
ATOM   859  O OG  A SER   A 1 131 ? -30.932 -31.910 -19.706 0.50 39.58  ? 504 SER   A OG  1 
ATOM   860  O OG  B SER   A 1 131 ? -28.971 -31.220 -20.502 0.50 32.32  ? 504 SER   A OG  1 
ATOM   861  N N   . PRO   A 1 132 ? -29.380 -32.294 -16.848 1.00 34.40  ? 505 PRO   A N   1 
ATOM   862  C CA  . PRO   A 1 132 ? -28.552 -33.353 -16.253 1.00 37.40  ? 505 PRO   A CA  1 
ATOM   863  C C   . PRO   A 1 132 ? -27.601 -34.048 -17.211 1.00 39.79  ? 505 PRO   A C   1 
ATOM   864  O O   . PRO   A 1 132 ? -26.540 -34.480 -16.799 1.00 45.70  ? 505 PRO   A O   1 
ATOM   865  C CB  . PRO   A 1 132 ? -29.602 -34.379 -15.694 1.00 37.57  ? 505 PRO   A CB  1 
ATOM   866  C CG  . PRO   A 1 132 ? -30.824 -33.501 -15.410 1.00 38.35  ? 505 PRO   A CG  1 
ATOM   867  C CD  . PRO   A 1 132 ? -30.792 -32.386 -16.468 1.00 34.43  ? 505 PRO   A CD  1 
ATOM   868  N N   . ASN   A 1 133 ? -28.027 -34.244 -18.463 1.00 40.47  ? 506 ASN   A N   1 
ATOM   869  C CA  . ASN   A 1 133 ? -27.219 -35.002 -19.406 1.00 42.86  ? 506 ASN   A CA  1 
ATOM   870  C C   . ASN   A 1 133 ? -26.219 -34.073 -20.088 1.00 41.70  ? 506 ASN   A C   1 
ATOM   871  O O   . ASN   A 1 133 ? -25.343 -34.549 -20.773 1.00 45.06  ? 506 ASN   A O   1 
ATOM   872  C CB  . ASN   A 1 133 ? -28.061 -35.806 -20.383 1.00 45.03  ? 506 ASN   A CB  1 
ATOM   873  C CG  . ASN   A 1 133 ? -28.672 -34.984 -21.503 1.00 48.54  ? 506 ASN   A CG  1 
ATOM   874  O OD1 . ASN   A 1 133 ? -28.523 -33.751 -21.594 1.00 45.87  ? 506 ASN   A OD1 1 
ATOM   875  N ND2 . ASN   A 1 133 ? -29.344 -35.674 -22.402 1.00 51.86  ? 506 ASN   A ND2 1 
ATOM   876  N N   . GLY   A 1 134 ? -26.334 -32.752 -19.876 1.00 39.52  ? 507 GLY   A N   1 
ATOM   877  C CA  . GLY   A 1 134 ? -25.256 -31.843 -20.264 1.00 40.55  ? 507 GLY   A CA  1 
ATOM   878  C C   . GLY   A 1 134 ? -25.346 -31.365 -21.723 1.00 43.10  ? 507 GLY   A C   1 
ATOM   879  O O   . GLY   A 1 134 ? -24.498 -30.596 -22.175 1.00 41.84  ? 507 GLY   A O   1 
ATOM   880  N N   . ALA   A 1 135 ? -26.380 -31.812 -22.452 1.00 44.72  ? 508 ALA   A N   1 
ATOM   881  C CA  . ALA   A 1 135 ? -26.504 -31.530 -23.871 1.00 48.28  ? 508 ALA   A CA  1 
ATOM   882  C C   . ALA   A 1 135 ? -27.269 -30.221 -24.088 1.00 46.37  ? 508 ALA   A C   1 
ATOM   883  O O   . ALA   A 1 135 ? -27.207 -29.653 -25.168 1.00 48.20  ? 508 ALA   A O   1 
ATOM   884  C CB  . ALA   A 1 135 ? -27.191 -32.691 -24.590 1.00 48.60  ? 508 ALA   A CB  1 
ATOM   885  N N   . SER   A 1 136 ? -27.973 -29.728 -23.065 1.00 45.55  ? 509 SER   A N   1 
ATOM   886  C CA  . SER   A 1 136 ? -28.836 -28.569 -23.256 1.00 43.89  ? 509 SER   A CA  1 
ATOM   887  C C   . SER   A 1 136 ? -28.889 -27.738 -21.990 1.00 41.72  ? 509 SER   A C   1 
ATOM   888  O O   . SER   A 1 136 ? -28.485 -28.192 -20.921 1.00 40.61  ? 509 SER   A O   1 
ATOM   889  C CB  . SER   A 1 136 ? -30.222 -28.957 -23.724 1.00 43.27  ? 509 SER   A CB  1 
ATOM   890  O OG  . SER   A 1 136 ? -30.955 -29.628 -22.718 1.00 45.30  ? 509 SER   A OG  1 
ATOM   891  N N   . PHE   A 1 137 ? -29.317 -26.485 -22.155 1.00 39.06  ? 510 PHE   A N   1 
ATOM   892  C CA  . PHE   A 1 137 ? -29.651 -25.649 -21.023 1.00 37.13  ? 510 PHE   A CA  1 
ATOM   893  C C   . PHE   A 1 137 ? -30.771 -24.702 -21.426 1.00 36.83  ? 510 PHE   A C   1 
ATOM   894  O O   . PHE   A 1 137 ? -31.047 -24.453 -22.595 1.00 42.20  ? 510 PHE   A O   1 
ATOM   895  C CB  . PHE   A 1 137 ? -28.445 -24.874 -20.466 1.00 37.47  ? 510 PHE   A CB  1 
ATOM   896  C CG  . PHE   A 1 137 ? -27.977 -23.678 -21.288 1.00 37.64  ? 510 PHE   A CG  1 
ATOM   897  C CD1 . PHE   A 1 137 ? -27.051 -23.830 -22.305 1.00 37.88  ? 510 PHE   A CD1 1 
ATOM   898  C CD2 . PHE   A 1 137 ? -28.472 -22.407 -21.052 1.00 35.95  ? 510 PHE   A CD2 1 
ATOM   899  C CE1 . PHE   A 1 137 ? -26.641 -22.742 -23.056 1.00 38.87  ? 510 PHE   A CE1 1 
ATOM   900  C CE2 . PHE   A 1 137 ? -28.058 -21.333 -21.819 1.00 35.11  ? 510 PHE   A CE2 1 
ATOM   901  C CZ  . PHE   A 1 137 ? -27.134 -21.500 -22.799 1.00 36.46  ? 510 PHE   A CZ  1 
ATOM   902  N N   . VAL   A 1 138 ? -31.414 -24.188 -20.421 1.00 35.46  ? 511 VAL   A N   1 
ATOM   903  C CA  . VAL   A 1 138 ? -32.509 -23.285 -20.591 1.00 34.89  ? 511 VAL   A CA  1 
ATOM   904  C C   . VAL   A 1 138 ? -32.162 -21.986 -19.876 1.00 34.83  ? 511 VAL   A C   1 
ATOM   905  O O   . VAL   A 1 138 ? -31.443 -21.986 -18.859 1.00 31.13  ? 511 VAL   A O   1 
ATOM   906  C CB  . VAL   A 1 138 ? -33.732 -23.972 -20.001 1.00 38.63  ? 511 VAL   A CB  1 
ATOM   907  C CG1 . VAL   A 1 138 ? -34.720 -22.982 -19.468 1.00 50.50  ? 511 VAL   A CG1 1 
ATOM   908  C CG2 . VAL   A 1 138 ? -34.393 -24.891 -21.005 1.00 40.32  ? 511 VAL   A CG2 1 
ATOM   909  N N   . CYS   A 1 139 ? -32.664 -20.878 -20.421 1.00 32.48  ? 512 CYS   A N   1 
ATOM   910  C CA  . CYS   A 1 139 ? -32.630 -19.642 -19.696 1.00 34.54  ? 512 CYS   A CA  1 
ATOM   911  C C   . CYS   A 1 139 ? -33.937 -18.910 -19.879 1.00 37.16  ? 512 CYS   A C   1 
ATOM   912  O O   . CYS   A 1 139 ? -34.678 -19.149 -20.836 1.00 34.81  ? 512 CYS   A O   1 
ATOM   913  C CB  . CYS   A 1 139 ? -31.424 -18.805 -20.058 1.00 36.04  ? 512 CYS   A CB  1 
ATOM   914  S SG  . CYS   A 1 139 ? -31.626 -17.889 -21.590 1.00 35.19  ? 512 CYS   A SG  1 
ATOM   915  N N   . SER   A 1 140 ? -34.270 -18.141 -18.839 1.00 35.33  ? 513 SER   A N   1 
ATOM   916  C CA  . SER   A 1 140 ? -35.343 -17.188 -18.927 1.00 36.45  ? 513 SER   A CA  1 
ATOM   917  C C   . SER   A 1 140 ? -34.740 -15.845 -19.301 1.00 36.93  ? 513 SER   A C   1 
ATOM   918  O O   . SER   A 1 140 ? -33.633 -15.511 -18.880 1.00 38.08  ? 513 SER   A O   1 
ATOM   919  C CB  . SER   A 1 140 ? -36.130 -17.111 -17.664 1.00 36.68  ? 513 SER   A CB  1 
ATOM   920  O OG  . SER   A 1 140 ? -35.460 -16.327 -16.705 1.00 44.89  ? 513 SER   A OG  1 
ATOM   921  N N   . ALA   A 1 141 ? -35.457 -15.115 -20.137 1.00 37.51  ? 514 ALA   A N   1 
ATOM   922  C CA  . ALA   A 1 141 ? -35.038 -13.787 -20.541 1.00 41.15  ? 514 ALA   A CA  1 
ATOM   923  C C   . ALA   A 1 141 ? -36.229 -12.864 -20.417 1.00 40.72  ? 514 ALA   A C   1 
ATOM   924  O O   . ALA   A 1 141 ? -37.262 -13.141 -21.026 1.00 45.24  ? 514 ALA   A O   1 
ATOM   925  C CB  . ALA   A 1 141 ? -34.522 -13.840 -21.955 1.00 43.01  ? 514 ALA   A CB  1 
ATOM   926  N N   . ALA   A 1 142 ? -36.094 -11.802 -19.617 1.00 40.30  ? 515 ALA   A N   1 
ATOM   927  C CA  . ALA   A 1 142 ? -37.229 -10.938 -19.314 1.00 41.38  ? 515 ALA   A CA  1 
ATOM   928  C C   . ALA   A 1 142 ? -36.978 -9.493  -19.755 1.00 44.36  ? 515 ALA   A C   1 
ATOM   929  O O   . ALA   A 1 142 ? -35.848 -9.010  -19.788 1.00 45.71  ? 515 ALA   A O   1 
ATOM   930  C CB  . ALA   A 1 142 ? -37.541 -10.994 -17.837 1.00 39.61  ? 515 ALA   A CB  1 
ATOM   931  N N   . ALA   A 1 143 ? -38.088 -8.804  -20.019 1.00 46.47  ? 516 ALA   A N   1 
ATOM   932  C CA  . ALA   A 1 143 ? -38.113 -7.384  -20.254 1.00 48.97  ? 516 ALA   A CA  1 
ATOM   933  C C   . ALA   A 1 143 ? -37.621 -6.632  -19.019 1.00 51.91  ? 516 ALA   A C   1 
ATOM   934  O O   . ALA   A 1 143 ? -37.487 -7.208  -17.941 1.00 52.96  ? 516 ALA   A O   1 
ATOM   935  C CB  . ALA   A 1 143 ? -39.521 -6.983  -20.620 1.00 50.24  ? 516 ALA   A CB  1 
ATOM   936  N N   . PRO   A 1 144 ? -37.308 -5.320  -19.150 1.00 54.51  ? 517 PRO   A N   1 
ATOM   937  C CA  . PRO   A 1 144 ? -36.932 -4.503  -17.991 1.00 55.10  ? 517 PRO   A CA  1 
ATOM   938  C C   . PRO   A 1 144 ? -38.112 -4.413  -17.029 1.00 57.06  ? 517 PRO   A C   1 
ATOM   939  O O   . PRO   A 1 144 ? -39.259 -4.375  -17.469 1.00 57.57  ? 517 PRO   A O   1 
ATOM   940  C CB  . PRO   A 1 144 ? -36.543 -3.133  -18.564 1.00 55.14  ? 517 PRO   A CB  1 
ATOM   941  C CG  . PRO   A 1 144 ? -36.456 -3.340  -20.089 1.00 57.33  ? 517 PRO   A CG  1 
ATOM   942  C CD  . PRO   A 1 144 ? -37.266 -4.583  -20.427 1.00 55.17  ? 517 PRO   A CD  1 
ATOM   943  N N   . SER   A 1 145 ? -37.835 -4.416  -15.719 1.00 58.49  ? 518 SER   A N   1 
ATOM   944  C CA  . SER   A 1 145 ? -38.903 -4.221  -14.744 1.00 65.67  ? 518 SER   A CA  1 
ATOM   945  C C   . SER   A 1 145 ? -39.405 -2.788  -14.833 1.00 68.77  ? 518 SER   A C   1 
ATOM   946  O O   . SER   A 1 145 ? -38.656 -1.904  -15.229 1.00 70.41  ? 518 SER   A O   1 
ATOM   947  C CB  . SER   A 1 145 ? -38.471 -4.574  -13.342 1.00 70.04  ? 518 SER   A CB  1 
ATOM   948  O OG  . SER   A 1 145 ? -37.172 -4.082  -13.062 1.00 69.56  ? 518 SER   A OG  1 
ATOM   949  N N   . LEU   A 1 146 ? -40.690 -2.588  -14.518 1.00 74.35  ? 519 LEU   A N   1 
ATOM   950  C CA  . LEU   A 1 146 ? -41.337 -1.291  -14.661 1.00 78.58  ? 519 LEU   A CA  1 
ATOM   951  C C   . LEU   A 1 146 ? -40.902 -0.358  -13.515 1.00 77.97  ? 519 LEU   A C   1 
ATOM   952  O O   . LEU   A 1 146 ? -40.455 -0.909  -12.464 1.00 70.57  ? 519 LEU   A O   1 
ATOM   953  C CB  . LEU   A 1 146 ? -42.850 -1.499  -14.679 1.00 84.78  ? 519 LEU   A CB  1 
ATOM   954  C CG  . LEU   A 1 146 ? -43.413 -2.243  -15.898 1.00 91.20  ? 519 LEU   A CG  1 
ATOM   955  C CD1 . LEU   A 1 146 ? -44.900 -2.554  -15.730 1.00 92.36  ? 519 LEU   A CD1 1 
ATOM   956  C CD2 . LEU   A 1 146 ? -43.181 -1.457  -17.186 1.00 94.61  ? 519 LEU   A CD2 1 
ATOM   957  N N   . MET   A 1 162 ? -45.106 -5.004  -11.079 1.00 77.61  ? 535 MET   A N   1 
ATOM   958  C CA  . MET   A 1 162 ? -43.723 -4.545  -10.777 1.00 80.52  ? 535 MET   A CA  1 
ATOM   959  C C   . MET   A 1 162 ? -42.735 -5.302  -11.669 1.00 82.36  ? 535 MET   A C   1 
ATOM   960  O O   . MET   A 1 162 ? -42.067 -4.707  -12.517 1.00 80.89  ? 535 MET   A O   1 
ATOM   961  C CB  . MET   A 1 162 ? -43.391 -4.761  -9.293  1.00 81.84  ? 535 MET   A CB  1 
ATOM   962  N N   . ASN   A 1 163 ? -42.648 -6.625  -11.471 1.00 76.93  ? 536 ASN   A N   1 
ATOM   963  C CA  . ASN   A 1 163 ? -41.972 -7.491  -12.420 1.00 73.95  ? 536 ASN   A CA  1 
ATOM   964  C C   . ASN   A 1 163 ? -43.011 -8.258  -13.250 1.00 68.43  ? 536 ASN   A C   1 
ATOM   965  O O   . ASN   A 1 163 ? -42.668 -9.266  -13.869 1.00 65.87  ? 536 ASN   A O   1 
ATOM   966  C CB  . ASN   A 1 163 ? -40.953 -8.401  -11.733 1.00 72.96  ? 536 ASN   A CB  1 
ATOM   967  N N   . GLN   A 1 164 ? -44.252 -7.728  -13.339 1.00 66.66  ? 537 GLN   A N   1 
ATOM   968  C CA  . GLN   A 1 164 ? -45.283 -8.278  -14.220 1.00 64.52  ? 537 GLN   A CA  1 
ATOM   969  C C   . GLN   A 1 164 ? -45.007 -7.912  -15.674 1.00 58.58  ? 537 GLN   A C   1 
ATOM   970  O O   . GLN   A 1 164 ? -45.828 -7.275  -16.318 1.00 60.06  ? 537 GLN   A O   1 
ATOM   971  C CB  . GLN   A 1 164 ? -46.671 -7.700  -13.942 1.00 77.33  ? 537 GLN   A CB  1 
ATOM   972  C CG  . GLN   A 1 164 ? -47.225 -8.042  -12.568 1.00 83.63  ? 537 GLN   A CG  1 
ATOM   973  C CD  . GLN   A 1 164 ? -47.210 -9.528  -12.310 1.00 75.50  ? 537 GLN   A CD  1 
ATOM   974  O OE1 . GLN   A 1 164 ? -47.938 -10.305 -12.952 1.00 62.84  ? 537 GLN   A OE1 1 
ATOM   975  N NE2 . GLN   A 1 164 ? -46.352 -9.927  -11.377 1.00 73.09  ? 537 GLN   A NE2 1 
ATOM   976  N N   . VAL   A 1 165 ? -43.855 -8.327  -16.192 1.00 53.76  ? 538 VAL   A N   1 
ATOM   977  C CA  . VAL   A 1 165 ? -43.413 -7.883  -17.500 1.00 54.63  ? 538 VAL   A CA  1 
ATOM   978  C C   . VAL   A 1 165 ? -43.206 -9.097  -18.400 1.00 50.79  ? 538 VAL   A C   1 
ATOM   979  O O   . VAL   A 1 165 ? -43.040 -10.227 -17.929 1.00 49.35  ? 538 VAL   A O   1 
ATOM   980  C CB  . VAL   A 1 165 ? -42.131 -7.031  -17.436 1.00 55.23  ? 538 VAL   A CB  1 
ATOM   981  C CG1 . VAL   A 1 165 ? -42.368 -5.692  -16.748 1.00 57.06  ? 538 VAL   A CG1 1 
ATOM   982  C CG2 . VAL   A 1 165 ? -40.983 -7.789  -16.781 1.00 51.90  ? 538 VAL   A CG2 1 
ATOM   983  N N   . PRO   A 1 166 ? -43.220 -8.889  -19.731 1.00 49.63  ? 539 PRO   A N   1 
ATOM   984  C CA  . PRO   A 1 166 ? -42.940 -9.963  -20.676 1.00 46.66  ? 539 PRO   A CA  1 
ATOM   985  C C   . PRO   A 1 166 ? -41.612 -10.646 -20.378 1.00 43.00  ? 539 PRO   A C   1 
ATOM   986  O O   . PRO   A 1 166 ? -40.666 -10.019 -19.924 1.00 43.36  ? 539 PRO   A O   1 
ATOM   987  C CB  . PRO   A 1 166 ? -42.946 -9.245  -22.026 1.00 49.10  ? 539 PRO   A CB  1 
ATOM   988  C CG  . PRO   A 1 166 ? -43.930 -8.093  -21.814 1.00 51.75  ? 539 PRO   A CG  1 
ATOM   989  C CD  . PRO   A 1 166 ? -43.608 -7.633  -20.393 1.00 51.64  ? 539 PRO   A CD  1 
ATOM   990  N N   . GLY   A 1 167 ? -41.588 -11.950 -20.606 1.00 39.64  ? 540 GLY   A N   1 
ATOM   991  C CA  . GLY   A 1 167 ? -40.357 -12.697 -20.645 1.00 39.69  ? 540 GLY   A CA  1 
ATOM   992  C C   . GLY   A 1 167 ? -40.503 -13.905 -21.545 1.00 38.69  ? 540 GLY   A C   1 
ATOM   993  O O   . GLY   A 1 167 ? -41.600 -14.221 -22.008 1.00 39.32  ? 540 GLY   A O   1 
ATOM   994  N N   . ARG   A 1 168 ? -39.372 -14.563 -21.782 1.00 41.33  ? 541 ARG   A N   1 
ATOM   995  C CA  . ARG   A 1 168 ? -39.322 -15.737 -22.632 1.00 43.94  ? 541 ARG   A CA  1 
ATOM   996  C C   . ARG   A 1 168 ? -38.578 -16.839 -21.902 1.00 38.98  ? 541 ARG   A C   1 
ATOM   997  O O   . ARG   A 1 168 ? -37.872 -16.571 -20.938 1.00 36.88  ? 541 ARG   A O   1 
ATOM   998  C CB  . ARG   A 1 168 ? -38.587 -15.446 -23.946 1.00 46.50  ? 541 ARG   A CB  1 
ATOM   999  C CG  . ARG   A 1 168 ? -39.165 -14.340 -24.820 1.00 51.86  ? 541 ARG   A CG  1 
ATOM   1000 C CD  . ARG   A 1 168 ? -38.366 -14.238 -26.130 1.00 57.88  ? 541 ARG   A CD  1 
ATOM   1001 N NE  . ARG   A 1 168 ? -38.636 -13.041 -26.946 1.00 65.18  ? 541 ARG   A NE  1 
ATOM   1002 C CZ  . ARG   A 1 168 ? -39.794 -12.699 -27.495 1.00 69.09  ? 541 ARG   A CZ  1 
ATOM   1003 N NH1 . ARG   A 1 168 ? -40.858 -13.480 -27.366 1.00 73.59  ? 541 ARG   A NH1 1 
ATOM   1004 N NH2 . ARG   A 1 168 ? -39.890 -11.564 -28.163 1.00 71.13  ? 541 ARG   A NH2 1 
ATOM   1005 N N   . LEU   A 1 169 ? -38.742 -18.061 -22.411 1.00 37.62  ? 542 LEU   A N   1 
ATOM   1006 C CA  . LEU   A 1 169 ? -38.027 -19.226 -21.958 1.00 36.29  ? 542 LEU   A CA  1 
ATOM   1007 C C   . LEU   A 1 169 ? -37.324 -19.871 -23.145 1.00 37.89  ? 542 LEU   A C   1 
ATOM   1008 O O   . LEU   A 1 169 ? -37.998 -20.389 -24.042 1.00 38.29  ? 542 LEU   A O   1 
ATOM   1009 C CB  . LEU   A 1 169 ? -39.038 -20.170 -21.336 1.00 36.33  ? 542 LEU   A CB  1 
ATOM   1010 C CG  . LEU   A 1 169 ? -38.443 -21.396 -20.650 1.00 37.39  ? 542 LEU   A CG  1 
ATOM   1011 C CD1 . LEU   A 1 169 ? -37.493 -21.022 -19.516 1.00 37.39  ? 542 LEU   A CD1 1 
ATOM   1012 C CD2 . LEU   A 1 169 ? -39.552 -22.253 -20.126 1.00 40.41  ? 542 LEU   A CD2 1 
ATOM   1013 N N   . LEU   A 1 170 ? -35.977 -19.878 -23.108 1.00 35.03  ? 543 LEU   A N   1 
ATOM   1014 C CA  . LEU   A 1 170 ? -35.157 -20.315 -24.224 1.00 36.46  ? 543 LEU   A CA  1 
ATOM   1015 C C   . LEU   A 1 170 ? -34.521 -21.680 -23.938 1.00 38.35  ? 543 LEU   A C   1 
ATOM   1016 O O   . LEU   A 1 170 ? -33.981 -21.892 -22.864 1.00 38.69  ? 543 LEU   A O   1 
ATOM   1017 C CB  . LEU   A 1 170 ? -34.069 -19.280 -24.463 1.00 37.40  ? 543 LEU   A CB  1 
ATOM   1018 C CG  . LEU   A 1 170 ? -34.473 -17.973 -25.142 1.00 39.55  ? 543 LEU   A CG  1 
ATOM   1019 C CD1 . LEU   A 1 170 ? -35.598 -17.256 -24.509 1.00 41.45  ? 543 LEU   A CD1 1 
ATOM   1020 C CD2 . LEU   A 1 170 ? -33.288 -17.104 -25.156 1.00 41.81  ? 543 LEU   A CD2 1 
ATOM   1021 N N   . LEU   A 1 171 ? -34.468 -22.538 -24.970 1.00 39.58  ? 544 LEU   A N   1 
ATOM   1022 C CA  . LEU   A 1 171 ? -33.754 -23.807 -24.927 1.00 39.39  ? 544 LEU   A CA  1 
ATOM   1023 C C   . LEU   A 1 171 ? -32.539 -23.706 -25.848 1.00 41.54  ? 544 LEU   A C   1 
ATOM   1024 O O   . LEU   A 1 171 ? -32.650 -23.213 -26.969 1.00 44.86  ? 544 LEU   A O   1 
ATOM   1025 C CB  . LEU   A 1 171 ? -34.682 -24.947 -25.360 1.00 38.47  ? 544 LEU   A CB  1 
ATOM   1026 C CG  . LEU   A 1 171 ? -34.066 -26.344 -25.492 1.00 39.00  ? 544 LEU   A CG  1 
ATOM   1027 C CD1 . LEU   A 1 171 ? -33.580 -26.924 -24.159 1.00 38.54  ? 544 LEU   A CD1 1 
ATOM   1028 C CD2 . LEU   A 1 171 ? -35.075 -27.280 -26.092 1.00 40.58  ? 544 LEU   A CD2 1 
ATOM   1029 N N   . TRP   A 1 172 ? -31.382 -24.156 -25.339 1.00 39.80  ? 545 TRP   A N   1 
ATOM   1030 C CA  . TRP   A 1 172 ? -30.129 -24.100 -26.062 1.00 42.21  ? 545 TRP   A CA  1 
ATOM   1031 C C   . TRP   A 1 172 ? -29.532 -25.490 -26.216 1.00 42.64  ? 545 TRP   A C   1 
ATOM   1032 O O   . TRP   A 1 172 ? -29.710 -26.340 -25.356 1.00 44.70  ? 545 TRP   A O   1 
ATOM   1033 C CB  . TRP   A 1 172 ? -29.116 -23.248 -25.305 1.00 42.69  ? 545 TRP   A CB  1 
ATOM   1034 C CG  . TRP   A 1 172 ? -29.523 -21.830 -25.067 1.00 44.51  ? 545 TRP   A CG  1 
ATOM   1035 C CD1 . TRP   A 1 172 ? -30.506 -21.357 -24.243 1.00 43.25  ? 545 TRP   A CD1 1 
ATOM   1036 C CD2 . TRP   A 1 172 ? -28.836 -20.682 -25.578 1.00 45.17  ? 545 TRP   A CD2 1 
ATOM   1037 N NE1 . TRP   A 1 172 ? -30.509 -19.988 -24.248 1.00 42.15  ? 545 TRP   A NE1 1 
ATOM   1038 C CE2 . TRP   A 1 172 ? -29.497 -19.548 -25.056 1.00 44.69  ? 545 TRP   A CE2 1 
ATOM   1039 C CE3 . TRP   A 1 172 ? -27.759 -20.511 -26.451 1.00 49.81  ? 545 TRP   A CE3 1 
ATOM   1040 C CZ2 . TRP   A 1 172 ? -29.104 -18.256 -25.378 1.00 50.51  ? 545 TRP   A CZ2 1 
ATOM   1041 C CZ3 . TRP   A 1 172 ? -27.378 -19.233 -26.783 1.00 57.12  ? 545 TRP   A CZ3 1 
ATOM   1042 C CH2 . TRP   A 1 172 ? -28.041 -18.119 -26.244 1.00 58.49  ? 545 TRP   A CH2 1 
ATOM   1043 N N   . ASP   A 1 173 ? -28.660 -25.605 -27.208 1.00 44.41  ? 546 ASP   A N   1 
ATOM   1044 C CA  . ASP   A 1 173 ? -27.743 -26.711 -27.383 1.00 47.19  ? 546 ASP   A CA  1 
ATOM   1045 C C   . ASP   A 1 173 ? -26.369 -26.304 -26.835 1.00 48.31  ? 546 ASP   A C   1 
ATOM   1046 O O   . ASP   A 1 173 ? -25.792 -25.322 -27.294 1.00 47.49  ? 546 ASP   A O   1 
ATOM   1047 C CB  . ASP   A 1 173 ? -27.662 -27.041 -28.865 1.00 51.86  ? 546 ASP   A CB  1 
ATOM   1048 C CG  . ASP   A 1 173 ? -26.671 -28.112 -29.255 1.00 54.14  ? 546 ASP   A CG  1 
ATOM   1049 O OD1 . ASP   A 1 173 ? -26.883 -29.262 -28.876 1.00 57.18  ? 546 ASP   A OD1 1 
ATOM   1050 O OD2 . ASP   A 1 173 ? -25.693 -27.772 -29.919 1.00 63.88  ? 546 ASP   A OD2 1 
ATOM   1051 N N   . THR   A 1 174 ? -25.840 -27.081 -25.870 1.00 47.03  ? 547 THR   A N   1 
ATOM   1052 C CA  . THR   A 1 174 ? -24.561 -26.779 -25.227 1.00 46.38  ? 547 THR   A CA  1 
ATOM   1053 C C   . THR   A 1 174 ? -23.407 -26.993 -26.187 1.00 48.36  ? 547 THR   A C   1 
ATOM   1054 O O   . THR   A 1 174 ? -22.398 -26.321 -26.068 1.00 53.22  ? 547 THR   A O   1 
ATOM   1055 C CB  . THR   A 1 174 ? -24.352 -27.614 -23.954 1.00 44.16  ? 547 THR   A CB  1 
ATOM   1056 O OG1 . THR   A 1 174 ? -24.396 -28.996 -24.306 1.00 44.18  ? 547 THR   A OG1 1 
ATOM   1057 C CG2 . THR   A 1 174 ? -25.404 -27.328 -22.907 1.00 40.97  ? 547 THR   A CG2 1 
ATOM   1058 N N   . LYS   A 1 175 ? -23.537 -27.932 -27.121 1.00 51.50  ? 548 LYS   A N   1 
ATOM   1059 C CA  . LYS   A 1 175 ? -22.417 -28.272 -27.966 1.00 55.83  ? 548 LYS   A CA  1 
ATOM   1060 C C   . LYS   A 1 175 ? -22.082 -27.079 -28.861 1.00 59.20  ? 548 LYS   A C   1 
ATOM   1061 O O   . LYS   A 1 175 ? -20.895 -26.820 -29.112 1.00 60.94  ? 548 LYS   A O   1 
ATOM   1062 C CB  . LYS   A 1 175 ? -22.657 -29.531 -28.813 1.00 60.00  ? 548 LYS   A CB  1 
ATOM   1063 N N   . THR   A 1 176 ? -23.128 -26.396 -29.380 1.00 55.67  ? 549 THR   A N   1 
ATOM   1064 C CA  . THR   A 1 176 ? -22.943 -25.302 -30.340 1.00 56.95  ? 549 THR   A CA  1 
ATOM   1065 C C   . THR   A 1 176 ? -23.084 -23.940 -29.644 1.00 55.18  ? 549 THR   A C   1 
ATOM   1066 O O   . THR   A 1 176 ? -22.670 -22.928 -30.205 1.00 55.98  ? 549 THR   A O   1 
ATOM   1067 C CB  . THR   A 1 176 ? -23.945 -25.410 -31.493 1.00 56.18  ? 549 THR   A CB  1 
ATOM   1068 O OG1 . THR   A 1 176 ? -25.240 -25.334 -30.906 1.00 50.68  ? 549 THR   A OG1 1 
ATOM   1069 C CG2 . THR   A 1 176 ? -23.796 -26.679 -32.306 1.00 58.36  ? 549 THR   A CG2 1 
ATOM   1070 N N   . MET   A 1 177 ? -23.681 -23.938 -28.441 1.00 52.06  ? 550 MET   A N   1 
ATOM   1071 C CA  . MET   A 1 177 ? -24.076 -22.730 -27.712 1.00 52.50  ? 550 MET   A CA  1 
ATOM   1072 C C   . MET   A 1 177 ? -24.979 -21.843 -28.575 1.00 56.51  ? 550 MET   A C   1 
ATOM   1073 O O   . MET   A 1 177 ? -24.865 -20.616 -28.537 1.00 54.31  ? 550 MET   A O   1 
ATOM   1074 C CB  . MET   A 1 177 ? -22.861 -21.936 -27.226 1.00 53.74  ? 550 MET   A CB  1 
ATOM   1075 C CG  . MET   A 1 177 ? -22.075 -22.629 -26.119 1.00 54.63  ? 550 MET   A CG  1 
ATOM   1076 S SD  . MET   A 1 177 ? -22.999 -22.871 -24.587 1.00 49.83  ? 550 MET   A SD  1 
ATOM   1077 C CE  . MET   A 1 177 ? -23.164 -21.151 -24.072 1.00 48.97  ? 550 MET   A CE  1 
ATOM   1078 N N   . LYS   A 1 178 ? -25.891 -22.487 -29.333 1.00 59.35  ? 551 LYS   A N   1 
ATOM   1079 C CA  . LYS   A 1 178 ? -26.914 -21.800 -30.110 1.00 56.28  ? 551 LYS   A CA  1 
ATOM   1080 C C   . LYS   A 1 178 ? -28.289 -22.107 -29.502 1.00 53.74  ? 551 LYS   A C   1 
ATOM   1081 O O   . LYS   A 1 178 ? -28.512 -23.171 -28.927 1.00 49.46  ? 551 LYS   A O   1 
ATOM   1082 C CB  . LYS   A 1 178 ? -26.756 -22.211 -31.577 1.00 59.55  ? 551 LYS   A CB  1 
ATOM   1083 C CG  . LYS   A 1 178 ? -25.516 -21.593 -32.280 1.00 63.95  ? 551 LYS   A CG  1 
ATOM   1084 C CD  . LYS   A 1 178 ? -25.240 -22.082 -33.698 1.00 70.12  ? 551 LYS   A CD  1 
ATOM   1085 C CE  . LYS   A 1 178 ? -24.110 -21.337 -34.445 1.00 74.13  ? 551 LYS   A CE  1 
ATOM   1086 N N   . GLN   A 1 179 ? -29.218 -21.160 -29.621 1.00 52.34  ? 552 GLN   A N   1 
ATOM   1087 C CA  . GLN   A 1 179 ? -30.592 -21.410 -29.249 1.00 49.72  ? 552 GLN   A CA  1 
ATOM   1088 C C   . GLN   A 1 179 ? -31.218 -22.434 -30.192 1.00 46.41  ? 552 GLN   A C   1 
ATOM   1089 O O   . GLN   A 1 179 ? -30.939 -22.433 -31.363 1.00 45.38  ? 552 GLN   A O   1 
ATOM   1090 C CB  . GLN   A 1 179 ? -31.446 -20.174 -29.399 1.00 51.32  ? 552 GLN   A CB  1 
ATOM   1091 C CG  . GLN   A 1 179 ? -31.079 -19.027 -28.492 1.00 53.39  ? 552 GLN   A CG  1 
ATOM   1092 C CD  . GLN   A 1 179 ? -32.096 -17.922 -28.643 1.00 55.72  ? 552 GLN   A CD  1 
ATOM   1093 O OE1 . GLN   A 1 179 ? -33.304 -18.144 -28.520 1.00 56.61  ? 552 GLN   A OE1 1 
ATOM   1094 N NE2 . GLN   A 1 179 ? -31.614 -16.753 -29.021 1.00 58.40  ? 552 GLN   A NE2 1 
ATOM   1095 N N   . GLN   A 1 180 ? -32.100 -23.284 -29.653 1.00 45.78  ? 553 GLN   A N   1 
ATOM   1096 C CA  . GLN   A 1 180 ? -32.853 -24.223 -30.471 1.00 46.60  ? 553 GLN   A CA  1 
ATOM   1097 C C   . GLN   A 1 180 ? -34.279 -23.721 -30.632 1.00 45.05  ? 553 GLN   A C   1 
ATOM   1098 O O   . GLN   A 1 180 ? -34.822 -23.718 -31.724 1.00 42.53  ? 553 GLN   A O   1 
ATOM   1099 C CB  . GLN   A 1 180 ? -32.856 -25.571 -29.769 1.00 47.73  ? 553 GLN   A CB  1 
ATOM   1100 C CG  . GLN   A 1 180 ? -33.512 -26.696 -30.564 1.00 49.83  ? 553 GLN   A CG  1 
ATOM   1101 C CD  . GLN   A 1 180 ? -33.550 -27.988 -29.778 1.00 50.50  ? 553 GLN   A CD  1 
ATOM   1102 O OE1 . GLN   A 1 180 ? -32.754 -28.182 -28.853 1.00 55.41  ? 553 GLN   A OE1 1 
ATOM   1103 N NE2 . GLN   A 1 180 ? -34.479 -28.870 -30.120 1.00 50.40  ? 553 GLN   A NE2 1 
ATOM   1104 N N   . LEU   A 1 181 ? -34.895 -23.330 -29.514 1.00 42.32  ? 554 LEU   A N   1 
ATOM   1105 C CA  . LEU   A 1 181 ? -36.276 -22.910 -29.592 1.00 43.28  ? 554 LEU   A CA  1 
ATOM   1106 C C   . LEU   A 1 181 ? -36.615 -22.090 -28.378 1.00 41.16  ? 554 LEU   A C   1 
ATOM   1107 O O   . LEU   A 1 181 ? -35.830 -22.022 -27.427 1.00 38.77  ? 554 LEU   A O   1 
ATOM   1108 C CB  . LEU   A 1 181 ? -37.198 -24.120 -29.739 1.00 43.65  ? 554 LEU   A CB  1 
ATOM   1109 C CG  . LEU   A 1 181 ? -37.173 -25.148 -28.604 1.00 42.16  ? 554 LEU   A CG  1 
ATOM   1110 C CD1 . LEU   A 1 181 ? -38.065 -24.739 -27.483 1.00 40.96  ? 554 LEU   A CD1 1 
ATOM   1111 C CD2 . LEU   A 1 181 ? -37.593 -26.527 -29.105 1.00 44.68  ? 554 LEU   A CD2 1 
ATOM   1112 N N   A GLN   A 1 182 ? -37.785 -21.443 -28.450 0.50 42.52  ? 555 GLN   A N   1 
ATOM   1113 N N   B GLN   A 1 182 ? -37.800 -21.483 -28.423 0.50 42.19  ? 555 GLN   A N   1 
ATOM   1114 C CA  A GLN   A 1 182 ? -38.411 -20.763 -27.322 0.50 41.14  ? 555 GLN   A CA  1 
ATOM   1115 C CA  B GLN   A 1 182 ? -38.371 -20.785 -27.284 0.50 40.69  ? 555 GLN   A CA  1 
ATOM   1116 C C   A GLN   A 1 182 ? -39.756 -21.423 -27.038 0.50 41.25  ? 555 GLN   A C   1 
ATOM   1117 C C   B GLN   A 1 182 ? -39.765 -21.356 -27.029 0.50 41.02  ? 555 GLN   A C   1 
ATOM   1118 O O   A GLN   A 1 182 ? -40.508 -21.721 -27.962 0.50 43.90  ? 555 GLN   A O   1 
ATOM   1119 O O   B GLN   A 1 182 ? -40.542 -21.556 -27.961 0.50 43.55  ? 555 GLN   A O   1 
ATOM   1120 C CB  A GLN   A 1 182 ? -38.698 -19.284 -27.612 0.50 42.57  ? 555 GLN   A CB  1 
ATOM   1121 C CB  B GLN   A 1 182 ? -38.443 -19.277 -27.546 0.50 41.92  ? 555 GLN   A CB  1 
ATOM   1122 C CG  A GLN   A 1 182 ? -40.128 -18.871 -27.245 0.50 43.33  ? 555 GLN   A CG  1 
ATOM   1123 C CG  B GLN   A 1 182 ? -37.130 -18.635 -28.000 0.50 43.62  ? 555 GLN   A CG  1 
ATOM   1124 C CD  A GLN   A 1 182 ? -40.427 -17.383 -27.356 0.50 42.36  ? 555 GLN   A CD  1 
ATOM   1125 C CD  B GLN   A 1 182 ? -37.273 -17.155 -28.323 0.50 45.01  ? 555 GLN   A CD  1 
ATOM   1126 O OE1 A GLN   A 1 182 ? -41.585 -16.958 -27.311 0.50 40.29  ? 555 GLN   A OE1 1 
ATOM   1127 O OE1 B GLN   A 1 182 ? -38.381 -16.609 -28.337 0.50 48.84  ? 555 GLN   A OE1 1 
ATOM   1128 N NE2 A GLN   A 1 182 ? -39.388 -16.599 -27.571 0.50 43.03  ? 555 GLN   A NE2 1 
ATOM   1129 N NE2 B GLN   A 1 182 ? -36.161 -16.484 -28.570 0.50 43.77  ? 555 GLN   A NE2 1 
ATOM   1130 N N   . PHE   A 1 183 ? -40.065 -21.600 -25.755 1.00 40.48  ? 556 PHE   A N   1 
ATOM   1131 C CA  . PHE   A 1 183 ? -41.352 -22.128 -25.319 1.00 40.67  ? 556 PHE   A CA  1 
ATOM   1132 C C   . PHE   A 1 183 ? -42.381 -21.004 -25.232 1.00 42.54  ? 556 PHE   A C   1 
ATOM   1133 O O   . PHE   A 1 183 ? -42.150 -20.002 -24.562 1.00 44.96  ? 556 PHE   A O   1 
ATOM   1134 C CB  . PHE   A 1 183 ? -41.167 -22.757 -23.937 1.00 36.97  ? 556 PHE   A CB  1 
ATOM   1135 C CG  . PHE   A 1 183 ? -40.256 -23.974 -23.897 1.00 37.52  ? 556 PHE   A CG  1 
ATOM   1136 C CD1 . PHE   A 1 183 ? -40.754 -25.239 -24.145 1.00 39.37  ? 556 PHE   A CD1 1 
ATOM   1137 C CD2 . PHE   A 1 183 ? -38.912 -23.854 -23.567 1.00 40.09  ? 556 PHE   A CD2 1 
ATOM   1138 C CE1 . PHE   A 1 183 ? -39.940 -26.342 -24.065 1.00 41.05  ? 556 PHE   A CE1 1 
ATOM   1139 C CE2 . PHE   A 1 183 ? -38.093 -24.977 -23.483 1.00 41.14  ? 556 PHE   A CE2 1 
ATOM   1140 C CZ  . PHE   A 1 183 ? -38.606 -26.211 -23.743 1.00 40.67  ? 556 PHE   A CZ  1 
ATOM   1141 N N   . SER   A 1 184 ? -43.521 -21.187 -25.899 1.00 42.89  ? 557 SER   A N   1 
ATOM   1142 C CA  . SER   A 1 184 ? -44.637 -20.285 -25.719 1.00 46.16  ? 557 SER   A CA  1 
ATOM   1143 C C   . SER   A 1 184 ? -45.093 -20.357 -24.262 1.00 45.49  ? 557 SER   A C   1 
ATOM   1144 O O   . SER   A 1 184 ? -45.055 -21.416 -23.650 1.00 42.53  ? 557 SER   A O   1 
ATOM   1145 C CB  . SER   A 1 184 ? -45.741 -20.596 -26.679 1.00 47.53  ? 557 SER   A CB  1 
ATOM   1146 O OG  . SER   A 1 184 ? -45.234 -20.583 -28.009 1.00 51.05  ? 557 SER   A OG  1 
ATOM   1147 N N   . LEU   A 1 185 ? -45.479 -19.206 -23.723 1.00 46.22  ? 558 LEU   A N   1 
ATOM   1148 C CA  . LEU   A 1 185 ? -45.962 -19.087 -22.353 1.00 44.26  ? 558 LEU   A CA  1 
ATOM   1149 C C   . LEU   A 1 185 ? -47.419 -18.667 -22.374 1.00 44.22  ? 558 LEU   A C   1 
ATOM   1150 O O   . LEU   A 1 185 ? -47.743 -17.635 -22.946 1.00 48.21  ? 558 LEU   A O   1 
ATOM   1151 C CB  . LEU   A 1 185 ? -45.111 -18.031 -21.652 1.00 41.45  ? 558 LEU   A CB  1 
ATOM   1152 C CG  . LEU   A 1 185 ? -43.628 -18.357 -21.529 1.00 39.84  ? 558 LEU   A CG  1 
ATOM   1153 C CD1 . LEU   A 1 185 ? -42.918 -17.224 -20.836 1.00 39.46  ? 558 LEU   A CD1 1 
ATOM   1154 C CD2 . LEU   A 1 185 ? -43.440 -19.675 -20.795 1.00 38.42  ? 558 LEU   A CD2 1 
ATOM   1155 N N   . ASP   A 1 186 ? -48.280 -19.438 -21.713 1.00 46.72  ? 559 ASP   A N   1 
ATOM   1156 C CA  . ASP   A 1 186 ? -49.698 -19.094 -21.688 1.00 50.85  ? 559 ASP   A CA  1 
ATOM   1157 C C   . ASP   A 1 186 ? -50.076 -18.519 -20.321 1.00 46.17  ? 559 ASP   A C   1 
ATOM   1158 O O   . ASP   A 1 186 ? -49.560 -18.976 -19.308 1.00 43.82  ? 559 ASP   A O   1 
ATOM   1159 C CB  . ASP   A 1 186 ? -50.534 -20.311 -22.024 1.00 56.58  ? 559 ASP   A CB  1 
ATOM   1160 C CG  . ASP   A 1 186 ? -51.900 -19.978 -22.592 1.00 67.05  ? 559 ASP   A CG  1 
ATOM   1161 O OD1 . ASP   A 1 186 ? -51.979 -19.735 -23.836 1.00 79.63  ? 559 ASP   A OD1 1 
ATOM   1162 O OD2 . ASP   A 1 186 ? -52.849 -19.865 -21.780 1.00 67.86  ? 559 ASP   A OD2 1 
ATOM   1163 N N   . PRO   A 1 187 ? -51.000 -17.528 -20.207 1.00 48.57  ? 560 PRO   A N   1 
ATOM   1164 C CA  . PRO   A 1 187 ? -51.727 -16.935 -21.341 1.00 52.11  ? 560 PRO   A CA  1 
ATOM   1165 C C   . PRO   A 1 187 ? -50.939 -15.892 -22.127 1.00 54.42  ? 560 PRO   A C   1 
ATOM   1166 O O   . PRO   A 1 187 ? -51.346 -15.505 -23.212 1.00 52.95  ? 560 PRO   A O   1 
ATOM   1167 C CB  . PRO   A 1 187 ? -52.952 -16.295 -20.641 1.00 51.30  ? 560 PRO   A CB  1 
ATOM   1168 C CG  . PRO   A 1 187 ? -52.422 -15.842 -19.304 1.00 49.15  ? 560 PRO   A CG  1 
ATOM   1169 C CD  . PRO   A 1 187 ? -51.408 -16.924 -18.927 1.00 48.69  ? 560 PRO   A CD  1 
ATOM   1170 N N   . GLU   A 1 188 ? -49.812 -15.454 -21.561 1.00 56.30  ? 561 GLU   A N   1 
ATOM   1171 C CA  . GLU   A 1 188 ? -49.006 -14.396 -22.145 1.00 57.95  ? 561 GLU   A CA  1 
ATOM   1172 C C   . GLU   A 1 188 ? -47.548 -14.575 -21.742 1.00 50.35  ? 561 GLU   A C   1 
ATOM   1173 O O   . GLU   A 1 188 ? -47.273 -15.089 -20.665 1.00 44.37  ? 561 GLU   A O   1 
ATOM   1174 C CB  . GLU   A 1 188 ? -49.353 -13.023 -21.576 1.00 63.85  ? 561 GLU   A CB  1 
ATOM   1175 C CG  . GLU   A 1 188 ? -50.714 -12.495 -21.990 1.00 73.74  ? 561 GLU   A CG  1 
ATOM   1176 C CD  . GLU   A 1 188 ? -50.823 -11.030 -21.652 1.00 77.71  ? 561 GLU   A CD  1 
ATOM   1177 O OE1 . GLU   A 1 188 ? -50.383 -10.627 -20.540 1.00 71.14  ? 561 GLU   A OE1 1 
ATOM   1178 O OE2 . GLU   A 1 188 ? -51.323 -10.295 -22.522 1.00 89.73  ? 561 GLU   A OE2 1 
ATOM   1179 N N   . PRO   A 1 189 ? -46.600 -14.056 -22.557 1.00 48.81  ? 562 PRO   A N   1 
ATOM   1180 C CA  . PRO   A 1 189 ? -45.205 -13.936 -22.155 1.00 46.27  ? 562 PRO   A CA  1 
ATOM   1181 C C   . PRO   A 1 189 ? -45.079 -13.294 -20.781 1.00 45.17  ? 562 PRO   A C   1 
ATOM   1182 O O   . PRO   A 1 189 ? -45.778 -12.341 -20.456 1.00 49.65  ? 562 PRO   A O   1 
ATOM   1183 C CB  . PRO   A 1 189 ? -44.535 -13.076 -23.283 1.00 47.59  ? 562 PRO   A CB  1 
ATOM   1184 C CG  . PRO   A 1 189 ? -45.424 -13.322 -24.512 1.00 48.98  ? 562 PRO   A CG  1 
ATOM   1185 C CD  . PRO   A 1 189 ? -46.835 -13.557 -23.934 1.00 51.32  ? 562 PRO   A CD  1 
ATOM   1186 N N   . ILE   A 1 190 ? -44.176 -13.833 -19.974 1.00 40.95  ? 563 ILE   A N   1 
ATOM   1187 C CA  . ILE   A 1 190 ? -44.065 -13.398 -18.602 1.00 40.92  ? 563 ILE   A CA  1 
ATOM   1188 C C   . ILE   A 1 190 ? -42.663 -13.729 -18.125 1.00 37.42  ? 563 ILE   A C   1 
ATOM   1189 O O   . ILE   A 1 190 ? -42.068 -14.719 -18.570 1.00 36.84  ? 563 ILE   A O   1 
ATOM   1190 C CB  . ILE   A 1 190 ? -45.166 -14.051 -17.738 1.00 41.36  ? 563 ILE   A CB  1 
ATOM   1191 C CG1 . ILE   A 1 190 ? -45.168 -13.511 -16.293 1.00 42.64  ? 563 ILE   A CG1 1 
ATOM   1192 C CG2 . ILE   A 1 190 ? -45.043 -15.582 -17.753 1.00 39.61  ? 563 ILE   A CG2 1 
ATOM   1193 C CD1 . ILE   A 1 190 ? -45.690 -12.093 -16.147 1.00 42.57  ? 563 ILE   A CD1 1 
ATOM   1194 N N   . ALA   A 1 191 ? -42.139 -12.886 -17.234 1.00 37.76  ? 564 ALA   A N   1 
ATOM   1195 C CA  . ALA   A 1 191 ? -40.822 -13.097 -16.662 1.00 37.34  ? 564 ALA   A CA  1 
ATOM   1196 C C   . ALA   A 1 191 ? -40.827 -14.373 -15.824 1.00 35.76  ? 564 ALA   A C   1 
ATOM   1197 O O   . ALA   A 1 191 ? -41.662 -14.532 -14.934 1.00 35.25  ? 564 ALA   A O   1 
ATOM   1198 C CB  . ALA   A 1 191 ? -40.420 -11.904 -15.841 1.00 39.10  ? 564 ALA   A CB  1 
ATOM   1199 N N   . ILE   A 1 192 ? -39.876 -15.264 -16.101 1.00 32.48  ? 565 ILE   A N   1 
ATOM   1200 C CA  . ILE   A 1 192 ? -39.719 -16.472 -15.317 1.00 35.28  ? 565 ILE   A CA  1 
ATOM   1201 C C   . ILE   A 1 192 ? -38.531 -16.322 -14.370 1.00 34.64  ? 565 ILE   A C   1 
ATOM   1202 O O   . ILE   A 1 192 ? -37.439 -15.985 -14.808 1.00 32.79  ? 565 ILE   A O   1 
ATOM   1203 C CB  . ILE   A 1 192 ? -39.621 -17.695 -16.254 1.00 38.82  ? 565 ILE   A CB  1 
ATOM   1204 C CG1 . ILE   A 1 192 ? -41.026 -18.012 -16.808 1.00 40.05  ? 565 ILE   A CG1 1 
ATOM   1205 C CG2 . ILE   A 1 192 ? -38.984 -18.894 -15.537 1.00 37.27  ? 565 ILE   A CG2 1 
ATOM   1206 C CD1 . ILE   A 1 192 ? -41.094 -19.140 -17.784 1.00 41.66  ? 565 ILE   A CD1 1 
ATOM   1207 N N   . ASN   A 1 193 ? -38.766 -16.584 -13.070 1.00 31.88  ? 566 ASN   A N   1 
ATOM   1208 C CA  . ASN   A 1 193 ? -37.769 -16.314 -12.035 1.00 33.67  ? 566 ASN   A CA  1 
ATOM   1209 C C   . ASN   A 1 193 ? -36.921 -17.546 -11.716 1.00 33.83  ? 566 ASN   A C   1 
ATOM   1210 O O   . ASN   A 1 193 ? -35.791 -17.426 -11.271 1.00 38.13  ? 566 ASN   A O   1 
ATOM   1211 C CB  . ASN   A 1 193 ? -38.424 -15.856 -10.746 1.00 33.60  ? 566 ASN   A CB  1 
ATOM   1212 C CG  . ASN   A 1 193 ? -39.202 -14.583 -10.927 1.00 33.73  ? 566 ASN   A CG  1 
ATOM   1213 O OD1 . ASN   A 1 193 ? -38.776 -13.694 -11.668 1.00 39.52  ? 566 ASN   A OD1 1 
ATOM   1214 N ND2 . ASN   A 1 193 ? -40.341 -14.475 -10.266 1.00 33.80  ? 566 ASN   A ND2 1 
ATOM   1215 N N   . CYS   A 1 194 ? -37.488 -18.735 -11.896 1.00 33.32  ? 567 CYS   A N   1 
ATOM   1216 C CA  . CYS   A 1 194 ? -36.827 -19.942 -11.453 1.00 31.61  ? 567 CYS   A CA  1 
ATOM   1217 C C   . CYS   A 1 194 ? -37.162 -21.123 -12.356 1.00 30.56  ? 567 CYS   A C   1 
ATOM   1218 O O   . CYS   A 1 194 ? -38.247 -21.199 -12.948 1.00 34.27  ? 567 CYS   A O   1 
ATOM   1219 C CB  . CYS   A 1 194 ? -37.176 -20.259 -10.007 1.00 32.84  ? 567 CYS   A CB  1 
ATOM   1220 S SG  . CYS   A 1 194 ? -38.944 -20.257 -9.654  1.00 34.12  ? 567 CYS   A SG  1 
ATOM   1221 N N   . THR   A 1 195 ? -36.200 -22.042 -12.425 1.00 31.48  ? 568 THR   A N   1 
ATOM   1222 C CA  . THR   A 1 195 ? -36.248 -23.203 -13.293 1.00 33.88  ? 568 THR   A CA  1 
ATOM   1223 C C   . THR   A 1 195 ? -35.579 -24.335 -12.546 1.00 35.64  ? 568 THR   A C   1 
ATOM   1224 O O   . THR   A 1 195 ? -34.564 -24.110 -11.884 1.00 31.42  ? 568 THR   A O   1 
ATOM   1225 C CB  . THR   A 1 195 ? -35.515 -22.945 -14.611 1.00 35.36  ? 568 THR   A CB  1 
ATOM   1226 O OG1 . THR   A 1 195 ? -34.207 -22.569 -14.198 1.00 34.84  ? 568 THR   A OG1 1 
ATOM   1227 C CG2 . THR   A 1 195 ? -36.144 -21.857 -15.449 1.00 36.81  ? 568 THR   A CG2 1 
ATOM   1228 N N   . ALA   A 1 196 ? -36.058 -25.562 -12.791 1.00 33.88  ? 569 ALA   A N   1 
ATOM   1229 C CA  . ALA   A 1 196 ? -35.360 -26.738 -12.313 1.00 34.85  ? 569 ALA   A CA  1 
ATOM   1230 C C   . ALA   A 1 196 ? -35.738 -27.926 -13.177 1.00 34.05  ? 569 ALA   A C   1 
ATOM   1231 O O   . ALA   A 1 196 ? -36.904 -28.107 -13.491 1.00 35.92  ? 569 ALA   A O   1 
ATOM   1232 C CB  . ALA   A 1 196 ? -35.718 -27.007 -10.843 1.00 33.97  ? 569 ALA   A CB  1 
ATOM   1233 N N   . PHE   A 1 197 ? -34.738 -28.750 -13.482 1.00 32.95  ? 570 PHE   A N   1 
ATOM   1234 C CA  . PHE   A 1 197 ? -34.943 -30.002 -14.183 1.00 34.28  ? 570 PHE   A CA  1 
ATOM   1235 C C   . PHE   A 1 197 ? -35.177 -31.089 -13.158 1.00 32.08  ? 570 PHE   A C   1 
ATOM   1236 O O   . PHE   A 1 197 ? -34.726 -30.960 -12.066 1.00 31.98  ? 570 PHE   A O   1 
ATOM   1237 C CB  . PHE   A 1 197 ? -33.758 -30.458 -15.034 1.00 32.53  ? 570 PHE   A CB  1 
ATOM   1238 C CG  . PHE   A 1 197 ? -33.598 -29.767 -16.373 1.00 32.92  ? 570 PHE   A CG  1 
ATOM   1239 C CD1 . PHE   A 1 197 ? -34.296 -30.204 -17.485 1.00 32.81  ? 570 PHE   A CD1 1 
ATOM   1240 C CD2 . PHE   A 1 197 ? -32.739 -28.680 -16.512 1.00 32.26  ? 570 PHE   A CD2 1 
ATOM   1241 C CE1 . PHE   A 1 197 ? -34.088 -29.610 -18.722 1.00 33.54  ? 570 PHE   A CE1 1 
ATOM   1242 C CE2 . PHE   A 1 197 ? -32.556 -28.074 -17.741 1.00 32.68  ? 570 PHE   A CE2 1 
ATOM   1243 C CZ  . PHE   A 1 197 ? -33.211 -28.550 -18.850 1.00 33.37  ? 570 PHE   A CZ  1 
ATOM   1244 N N   . ASN   A 1 198 ? -35.796 -32.186 -13.583 1.00 34.84  ? 571 ASN   A N   1 
ATOM   1245 C CA  . ASN   A 1 198 ? -35.867 -33.407 -12.807 1.00 36.55  ? 571 ASN   A CA  1 
ATOM   1246 C C   . ASN   A 1 198 ? -34.593 -34.218 -13.043 1.00 40.19  ? 571 ASN   A C   1 
ATOM   1247 O O   . ASN   A 1 198 ? -33.653 -33.734 -13.675 1.00 44.63  ? 571 ASN   A O   1 
ATOM   1248 C CB  . ASN   A 1 198 ? -37.150 -34.171 -13.126 1.00 36.38  ? 571 ASN   A CB  1 
ATOM   1249 C CG  . ASN   A 1 198 ? -37.104 -34.804 -14.495 1.00 36.68  ? 571 ASN   A CG  1 
ATOM   1250 O OD1 . ASN   A 1 198 ? -36.376 -34.345 -15.373 1.00 34.83  ? 571 ASN   A OD1 1 
ATOM   1251 N ND2 . ASN   A 1 198 ? -37.893 -35.839 -14.704 1.00 38.79  ? 571 ASN   A ND2 1 
ATOM   1252 N N   . HIS   A 1 199 ? -34.544 -35.437 -12.489 1.00 38.62  ? 572 HIS   A N   1 
ATOM   1253 C CA  . HIS   A 1 199 ? -33.290 -36.153 -12.380 1.00 45.76  ? 572 HIS   A CA  1 
ATOM   1254 C C   . HIS   A 1 199 ? -32.789 -36.535 -13.780 1.00 44.16  ? 572 HIS   A C   1 
ATOM   1255 O O   . HIS   A 1 199 ? -31.603 -36.429 -14.043 1.00 46.95  ? 572 HIS   A O   1 
ATOM   1256 C CB  . HIS   A 1 199 ? -33.390 -37.362 -11.412 1.00 53.08  ? 572 HIS   A CB  1 
ATOM   1257 C CG  . HIS   A 1 199 ? -32.096 -38.132 -11.222 1.00 69.08  ? 572 HIS   A CG  1 
ATOM   1258 N ND1 . HIS   A 1 199 ? -31.847 -39.385 -11.776 1.00 81.83  ? 572 HIS   A ND1 1 
ATOM   1259 C CD2 . HIS   A 1 199 ? -30.970 -37.821 -10.513 1.00 75.31  ? 572 HIS   A CD2 1 
ATOM   1260 C CE1 . HIS   A 1 199 ? -30.623 -39.802 -11.428 1.00 77.60  ? 572 HIS   A CE1 1 
ATOM   1261 N NE2 . HIS   A 1 199 ? -30.076 -38.873 -10.653 1.00 78.15  ? 572 HIS   A NE2 1 
ATOM   1262 N N   . ASN   A 1 200 ? -33.665 -37.069 -14.634 1.00 43.52  ? 573 ASN   A N   1 
ATOM   1263 C CA  . ASN   A 1 200 ? -33.244 -37.510 -15.954 1.00 49.29  ? 573 ASN   A CA  1 
ATOM   1264 C C   . ASN   A 1 200 ? -33.376 -36.370 -16.988 1.00 47.13  ? 573 ASN   A C   1 
ATOM   1265 O O   . ASN   A 1 200 ? -32.944 -36.531 -18.110 1.00 47.72  ? 573 ASN   A O   1 
ATOM   1266 C CB  . ASN   A 1 200 ? -33.942 -38.812 -16.331 1.00 59.01  ? 573 ASN   A CB  1 
ATOM   1267 C CG  . ASN   A 1 200 ? -35.303 -38.594 -16.946 1.00 72.35  ? 573 ASN   A CG  1 
ATOM   1268 O OD1 . ASN   A 1 200 ? -35.653 -39.250 -17.934 1.00 95.15  ? 573 ASN   A OD1 1 
ATOM   1269 N ND2 . ASN   A 1 200 ? -36.111 -37.728 -16.357 1.00 72.52  ? 573 ASN   A ND2 1 
ATOM   1270 N N   . GLY   A 1 201 ? -33.969 -35.217 -16.615 1.00 40.62  ? 574 GLY   A N   1 
ATOM   1271 C CA  . GLY   A 1 201 ? -33.960 -34.048 -17.468 1.00 39.05  ? 574 GLY   A CA  1 
ATOM   1272 C C   . GLY   A 1 201 ? -35.081 -34.035 -18.511 1.00 41.26  ? 574 GLY   A C   1 
ATOM   1273 O O   . GLY   A 1 201 ? -35.161 -33.104 -19.303 1.00 42.07  ? 574 GLY   A O   1 
ATOM   1274 N N   . ASN   A 1 202 ? -36.020 -34.985 -18.452 1.00 41.40  ? 575 ASN   A N   1 
ATOM   1275 C CA  . ASN   A 1 202 ? -37.172 -34.937 -19.357 1.00 41.95  ? 575 ASN   A CA  1 
ATOM   1276 C C   . ASN   A 1 202 ? -38.285 -34.000 -18.865 1.00 38.79  ? 575 ASN   A C   1 
ATOM   1277 O O   . ASN   A 1 202 ? -39.228 -33.777 -19.611 1.00 37.09  ? 575 ASN   A O   1 
ATOM   1278 C CB  . ASN   A 1 202 ? -37.735 -36.325 -19.631 1.00 50.40  ? 575 ASN   A CB  1 
ATOM   1279 C CG  . ASN   A 1 202 ? -38.376 -36.915 -18.396 1.00 57.82  ? 575 ASN   A CG  1 
ATOM   1280 O OD1 . ASN   A 1 202 ? -37.720 -37.019 -17.354 1.00 61.40  ? 575 ASN   A OD1 1 
ATOM   1281 N ND2 . ASN   A 1 202 ? -39.641 -37.311 -18.480 1.00 59.46  ? 575 ASN   A ND2 1 
ATOM   1282 N N   . LEU   A 1 203 ? -38.196 -33.435 -17.624 1.00 37.61  ? 576 LEU   A N   1 
ATOM   1283 C CA  . LEU   A 1 203 ? -39.161 -32.437 -17.160 1.00 33.93  ? 576 LEU   A CA  1 
ATOM   1284 C C   . LEU   A 1 203 ? -38.400 -31.238 -16.596 1.00 33.29  ? 576 LEU   A C   1 
ATOM   1285 O O   . LEU   A 1 203 ? -37.330 -31.379 -16.007 1.00 35.65  ? 576 LEU   A O   1 
ATOM   1286 C CB  . LEU   A 1 203 ? -40.158 -32.949 -16.121 1.00 35.43  ? 576 LEU   A CB  1 
ATOM   1287 C CG  . LEU   A 1 203 ? -40.984 -34.193 -16.487 1.00 39.70  ? 576 LEU   A CG  1 
ATOM   1288 C CD1 . LEU   A 1 203 ? -41.658 -34.758 -15.218 1.00 40.52  ? 576 LEU   A CD1 1 
ATOM   1289 C CD2 . LEU   A 1 203 ? -42.052 -33.894 -17.552 1.00 39.94  ? 576 LEU   A CD2 1 
ATOM   1290 N N   . LEU   A 1 204 ? -38.962 -30.060 -16.841 1.00 31.77  ? 577 LEU   A N   1 
ATOM   1291 C CA  . LEU   A 1 204 ? -38.477 -28.797 -16.328 1.00 32.39  ? 577 LEU   A CA  1 
ATOM   1292 C C   . LEU   A 1 204 ? -39.627 -28.072 -15.653 1.00 31.37  ? 577 LEU   A C   1 
ATOM   1293 O O   . LEU   A 1 204 ? -40.667 -27.814 -16.272 1.00 30.60  ? 577 LEU   A O   1 
ATOM   1294 C CB  . LEU   A 1 204 ? -37.958 -27.938 -17.470 1.00 33.92  ? 577 LEU   A CB  1 
ATOM   1295 C CG  . LEU   A 1 204 ? -37.456 -26.559 -17.042 1.00 33.72  ? 577 LEU   A CG  1 
ATOM   1296 C CD1 . LEU   A 1 204 ? -36.043 -26.637 -16.536 1.00 34.71  ? 577 LEU   A CD1 1 
ATOM   1297 C CD2 . LEU   A 1 204 ? -37.558 -25.591 -18.174 1.00 37.51  ? 577 LEU   A CD2 1 
ATOM   1298 N N   . VAL   A 1 205 ? -39.433 -27.700 -14.403 1.00 30.63  ? 578 VAL   A N   1 
ATOM   1299 C CA  . VAL   A 1 205 ? -40.467 -26.936 -13.747 1.00 31.41  ? 578 VAL   A CA  1 
ATOM   1300 C C   . VAL   A 1 205 ? -40.002 -25.491 -13.637 1.00 29.94  ? 578 VAL   A C   1 
ATOM   1301 O O   . VAL   A 1 205 ? -38.813 -25.236 -13.431 1.00 29.81  ? 578 VAL   A O   1 
ATOM   1302 C CB  . VAL   A 1 205 ? -40.832 -27.552 -12.387 1.00 33.00  ? 578 VAL   A CB  1 
ATOM   1303 C CG1 . VAL   A 1 205 ? -39.674 -27.468 -11.398 1.00 32.10  ? 578 VAL   A CG1 1 
ATOM   1304 C CG2 . VAL   A 1 205 ? -42.083 -26.904 -11.798 1.00 35.16  ? 578 VAL   A CG2 1 
ATOM   1305 N N   . THR   A 1 206 ? -40.977 -24.559 -13.699 1.00 30.46  ? 579 THR   A N   1 
ATOM   1306 C CA  . THR   A 1 206 ? -40.694 -23.140 -13.715 1.00 31.11  ? 579 THR   A CA  1 
ATOM   1307 C C   . THR   A 1 206 ? -41.710 -22.393 -12.858 1.00 30.09  ? 579 THR   A C   1 
ATOM   1308 O O   . THR   A 1 206 ? -42.876 -22.756 -12.764 1.00 32.75  ? 579 THR   A O   1 
ATOM   1309 C CB  . THR   A 1 206 ? -40.698 -22.587 -15.153 1.00 33.82  ? 579 THR   A CB  1 
ATOM   1310 O OG1 . THR   A 1 206 ? -42.042 -22.554 -15.633 1.00 30.78  ? 579 THR   A OG1 1 
ATOM   1311 C CG2 . THR   A 1 206 ? -39.825 -23.399 -16.087 1.00 35.99  ? 579 THR   A CG2 1 
ATOM   1312 N N   . GLY   A 1 207 ? -41.247 -21.276 -12.309 1.00 30.28  ? 580 GLY   A N   1 
ATOM   1313 C CA  . GLY   A 1 207 ? -42.092 -20.344 -11.601 1.00 30.38  ? 580 GLY   A CA  1 
ATOM   1314 C C   . GLY   A 1 207 ? -41.870 -18.941 -12.133 1.00 31.30  ? 580 GLY   A C   1 
ATOM   1315 O O   . GLY   A 1 207 ? -40.738 -18.557 -12.402 1.00 33.37  ? 580 GLY   A O   1 
ATOM   1316 N N   . ALA   A 1 208 ? -42.964 -18.189 -12.241 1.00 35.40  ? 581 ALA   A N   1 
ATOM   1317 C CA  . ALA   A 1 208 ? -42.956 -16.925 -12.939 1.00 36.90  ? 581 ALA   A CA  1 
ATOM   1318 C C   . ALA   A 1 208 ? -43.489 -15.805 -12.054 1.00 37.44  ? 581 ALA   A C   1 
ATOM   1319 O O   . ALA   A 1 208 ? -44.059 -16.043 -10.986 1.00 34.53  ? 581 ALA   A O   1 
ATOM   1320 C CB  . ALA   A 1 208 ? -43.782 -17.043 -14.200 1.00 39.30  ? 581 ALA   A CB  1 
ATOM   1321 N N   . ALA   A 1 209 ? -43.423 -14.593 -12.622 1.00 38.03  ? 582 ALA   A N   1 
ATOM   1322 C CA  . ALA   A 1 209 ? -43.771 -13.370 -11.939 1.00 40.44  ? 582 ALA   A CA  1 
ATOM   1323 C C   . ALA   A 1 209 ? -45.288 -13.251 -11.787 1.00 39.80  ? 582 ALA   A C   1 
ATOM   1324 O O   . ALA   A 1 209 ? -45.744 -12.546 -10.905 1.00 42.99  ? 582 ALA   A O   1 
ATOM   1325 C CB  . ALA   A 1 209 ? -43.175 -12.183 -12.694 1.00 42.36  ? 582 ALA   A CB  1 
ATOM   1326 N N   . ASP   A 1 210 ? -46.057 -13.995 -12.594 1.00 39.16  ? 583 ASP   A N   1 
ATOM   1327 C CA  . ASP   A 1 210 ? -47.516 -14.007 -12.498 1.00 38.23  ? 583 ASP   A CA  1 
ATOM   1328 C C   . ASP   A 1 210 ? -48.012 -15.008 -11.441 1.00 39.28  ? 583 ASP   A C   1 
ATOM   1329 O O   . ASP   A 1 210 ? -49.219 -15.232 -11.323 1.00 43.82  ? 583 ASP   A O   1 
ATOM   1330 C CB  . ASP   A 1 210 ? -48.166 -14.275 -13.856 1.00 39.21  ? 583 ASP   A CB  1 
ATOM   1331 C CG  . ASP   A 1 210 ? -47.869 -15.618 -14.513 1.00 39.92  ? 583 ASP   A CG  1 
ATOM   1332 O OD1 . ASP   A 1 210 ? -47.008 -16.352 -13.983 1.00 38.01  ? 583 ASP   A OD1 1 
ATOM   1333 O OD2 . ASP   A 1 210 ? -48.507 -15.920 -15.573 1.00 42.60  ? 583 ASP   A OD2 1 
ATOM   1334 N N   . GLY   A 1 211 ? -47.099 -15.601 -10.660 1.00 37.38  ? 584 GLY   A N   1 
ATOM   1335 C CA  . GLY   A 1 211 ? -47.473 -16.558 -9.637  1.00 39.19  ? 584 GLY   A CA  1 
ATOM   1336 C C   . GLY   A 1 211 ? -47.775 -17.956 -10.193 1.00 40.80  ? 584 GLY   A C   1 
ATOM   1337 O O   . GLY   A 1 211 ? -48.238 -18.808 -9.448  1.00 39.77  ? 584 GLY   A O   1 
ATOM   1338 N N   . VAL   A 1 212 ? -47.494 -18.196 -11.490 1.00 39.62  ? 585 VAL   A N   1 
ATOM   1339 C CA  . VAL   A 1 212 ? -47.908 -19.431 -12.143 1.00 38.60  ? 585 VAL   A CA  1 
ATOM   1340 C C   . VAL   A 1 212 ? -46.717 -20.383 -12.237 1.00 36.41  ? 585 VAL   A C   1 
ATOM   1341 O O   . VAL   A 1 212 ? -45.586 -19.966 -12.506 1.00 34.77  ? 585 VAL   A O   1 
ATOM   1342 C CB  . VAL   A 1 212 ? -48.524 -19.222 -13.540 1.00 39.01  ? 585 VAL   A CB  1 
ATOM   1343 C CG1 . VAL   A 1 212 ? -48.864 -20.549 -14.199 1.00 39.13  ? 585 VAL   A CG1 1 
ATOM   1344 C CG2 . VAL   A 1 212 ? -49.763 -18.338 -13.508 1.00 38.74  ? 585 VAL   A CG2 1 
ATOM   1345 N N   . ILE   A 1 213 ? -46.987 -21.678 -12.000 1.00 37.12  ? 586 ILE   A N   1 
ATOM   1346 C CA  . ILE   A 1 213 ? -45.989 -22.718 -12.200 1.00 34.35  ? 586 ILE   A CA  1 
ATOM   1347 C C   . ILE   A 1 213 ? -46.289 -23.391 -13.531 1.00 35.44  ? 586 ILE   A C   1 
ATOM   1348 O O   . ILE   A 1 213 ? -47.415 -23.760 -13.795 1.00 37.15  ? 586 ILE   A O   1 
ATOM   1349 C CB  . ILE   A 1 213 ? -45.957 -23.733 -11.040 1.00 32.78  ? 586 ILE   A CB  1 
ATOM   1350 C CG1 . ILE   A 1 213 ? -45.398 -23.122 -9.785  1.00 32.79  ? 586 ILE   A CG1 1 
ATOM   1351 C CG2 . ILE   A 1 213 ? -45.169 -24.982 -11.423 1.00 31.58  ? 586 ILE   A CG2 1 
ATOM   1352 C CD1 . ILE   A 1 213 ? -45.269 -24.083 -8.612  1.00 33.71  ? 586 ILE   A CD1 1 
ATOM   1353 N N   . ARG   A 1 214 ? -45.264 -23.511 -14.357 1.00 33.54  ? 587 ARG   A N   1 
ATOM   1354 C CA  . ARG   A 1 214 ? -45.391 -24.149 -15.640 1.00 33.88  ? 587 ARG   A CA  1 
ATOM   1355 C C   . ARG   A 1 214 ? -44.411 -25.308 -15.684 1.00 33.03  ? 587 ARG   A C   1 
ATOM   1356 O O   . ARG   A 1 214 ? -43.217 -25.126 -15.453 1.00 31.98  ? 587 ARG   A O   1 
ATOM   1357 C CB  . ARG   A 1 214 ? -45.114 -23.121 -16.742 1.00 33.56  ? 587 ARG   A CB  1 
ATOM   1358 C CG  . ARG   A 1 214 ? -46.186 -22.040 -16.836 1.00 32.82  ? 587 ARG   A CG  1 
ATOM   1359 C CD  . ARG   A 1 214 ? -45.822 -20.962 -17.823 1.00 32.28  ? 587 ARG   A CD  1 
ATOM   1360 N NE  . ARG   A 1 214 ? -46.800 -19.877 -17.889 1.00 34.66  ? 587 ARG   A NE  1 
ATOM   1361 C CZ  . ARG   A 1 214 ? -46.948 -18.961 -16.962 1.00 37.76  ? 587 ARG   A CZ  1 
ATOM   1362 N NH1 . ARG   A 1 214 ? -45.994 -18.786 -16.047 1.00 37.60  ? 587 ARG   A NH1 1 
ATOM   1363 N NH2 . ARG   A 1 214 ? -47.996 -18.163 -16.996 1.00 38.89  ? 587 ARG   A NH2 1 
ATOM   1364 N N   . LEU   A 1 215 ? -44.940 -26.501 -15.986 1.00 35.97  ? 588 LEU   A N   1 
ATOM   1365 C CA  . LEU   A 1 215 ? -44.116 -27.691 -16.080 1.00 36.52  ? 588 LEU   A CA  1 
ATOM   1366 C C   . LEU   A 1 215 ? -44.042 -28.148 -17.531 1.00 37.79  ? 588 LEU   A C   1 
ATOM   1367 O O   . LEU   A 1 215 ? -45.072 -28.328 -18.185 1.00 40.81  ? 588 LEU   A O   1 
ATOM   1368 C CB  . LEU   A 1 215 ? -44.660 -28.785 -15.186 1.00 38.08  ? 588 LEU   A CB  1 
ATOM   1369 C CG  . LEU   A 1 215 ? -43.962 -30.138 -15.322 1.00 42.45  ? 588 LEU   A CG  1 
ATOM   1370 C CD1 . LEU   A 1 215 ? -42.763 -30.240 -14.415 1.00 40.71  ? 588 LEU   A CD1 1 
ATOM   1371 C CD2 . LEU   A 1 215 ? -44.946 -31.247 -15.037 1.00 48.09  ? 588 LEU   A CD2 1 
ATOM   1372 N N   . PHE   A 1 216 ? -42.802 -28.376 -17.994 1.00 37.05  ? 589 PHE   A N   1 
ATOM   1373 C CA  . PHE   A 1 216 ? -42.529 -28.590 -19.412 1.00 38.87  ? 589 PHE   A CA  1 
ATOM   1374 C C   . PHE   A 1 216 ? -41.981 -29.981 -19.642 1.00 35.94  ? 589 PHE   A C   1 
ATOM   1375 O O   . PHE   A 1 216 ? -41.074 -30.435 -18.967 1.00 35.76  ? 589 PHE   A O   1 
ATOM   1376 C CB  . PHE   A 1 216 ? -41.509 -27.609 -19.989 1.00 38.10  ? 589 PHE   A CB  1 
ATOM   1377 C CG  . PHE   A 1 216 ? -42.086 -26.217 -20.081 1.00 36.37  ? 589 PHE   A CG  1 
ATOM   1378 C CD1 . PHE   A 1 216 ? -42.838 -25.839 -21.180 1.00 40.66  ? 589 PHE   A CD1 1 
ATOM   1379 C CD2 . PHE   A 1 216 ? -41.939 -25.323 -19.042 1.00 35.43  ? 589 PHE   A CD2 1 
ATOM   1380 C CE1 . PHE   A 1 216 ? -43.417 -24.578 -21.243 1.00 41.25  ? 589 PHE   A CE1 1 
ATOM   1381 C CE2 . PHE   A 1 216 ? -42.540 -24.067 -19.097 1.00 36.62  ? 589 PHE   A CE2 1 
ATOM   1382 C CZ  . PHE   A 1 216 ? -43.261 -23.697 -20.193 1.00 39.94  ? 589 PHE   A CZ  1 
ATOM   1383 N N   . ASP   A 1 217 ? -42.561 -30.629 -20.621 1.00 37.48  ? 590 ASP   A N   1 
ATOM   1384 C CA  . ASP   A 1 217 ? -42.054 -31.867 -21.142 1.00 39.50  ? 590 ASP   A CA  1 
ATOM   1385 C C   . ASP   A 1 217 ? -40.966 -31.515 -22.150 1.00 39.65  ? 590 ASP   A C   1 
ATOM   1386 O O   . ASP   A 1 217 ? -41.248 -30.917 -23.169 1.00 40.60  ? 590 ASP   A O   1 
ATOM   1387 C CB  . ASP   A 1 217 ? -43.225 -32.681 -21.653 1.00 40.86  ? 590 ASP   A CB  1 
ATOM   1388 C CG  . ASP   A 1 217 ? -42.867 -33.921 -22.425 1.00 44.19  ? 590 ASP   A CG  1 
ATOM   1389 O OD1 . ASP   A 1 217 ? -41.665 -34.135 -22.683 1.00 44.29  ? 590 ASP   A OD1 1 
ATOM   1390 O OD2 . ASP   A 1 217 ? -43.807 -34.613 -22.823 1.00 52.68  ? 590 ASP   A OD2 1 
ATOM   1391 N N   . MET   A 1 218 ? -39.727 -31.888 -21.839 1.00 39.72  ? 591 MET   A N   1 
ATOM   1392 C CA  . MET   A 1 218 ? -38.573 -31.463 -22.598 1.00 41.34  ? 591 MET   A CA  1 
ATOM   1393 C C   . MET   A 1 218 ? -38.289 -32.425 -23.730 1.00 45.63  ? 591 MET   A C   1 
ATOM   1394 O O   . MET   A 1 218 ? -37.262 -32.299 -24.385 1.00 47.12  ? 591 MET   A O   1 
ATOM   1395 C CB  . MET   A 1 218 ? -37.356 -31.359 -21.686 1.00 39.83  ? 591 MET   A CB  1 
ATOM   1396 C CG  . MET   A 1 218 ? -37.597 -30.382 -20.534 1.00 39.87  ? 591 MET   A CG  1 
ATOM   1397 S SD  . MET   A 1 218 ? -37.984 -28.697 -21.082 1.00 38.95  ? 591 MET   A SD  1 
ATOM   1398 C CE  . MET   A 1 218 ? -36.294 -28.313 -21.542 1.00 40.41  ? 591 MET   A CE  1 
ATOM   1399 N N   . GLN   A 1 219 ? -39.209 -33.356 -23.985 1.00 48.42  ? 592 GLN   A N   1 
ATOM   1400 C CA  . GLN   A 1 219 ? -39.062 -34.256 -25.124 1.00 54.28  ? 592 GLN   A CA  1 
ATOM   1401 C C   . GLN   A 1 219 ? -39.969 -33.777 -26.257 1.00 50.54  ? 592 GLN   A C   1 
ATOM   1402 O O   . GLN   A 1 219 ? -39.524 -33.644 -27.378 1.00 51.54  ? 592 GLN   A O   1 
ATOM   1403 C CB  . GLN   A 1 219 ? -39.348 -35.722 -24.763 1.00 60.50  ? 592 GLN   A CB  1 
ATOM   1404 C CG  . GLN   A 1 219 ? -38.253 -36.383 -23.916 1.00 66.88  ? 592 GLN   A CG  1 
ATOM   1405 C CD  . GLN   A 1 219 ? -38.548 -37.836 -23.563 1.00 75.85  ? 592 GLN   A CD  1 
ATOM   1406 O OE1 . GLN   A 1 219 ? -39.396 -38.147 -22.717 1.00 72.27  ? 592 GLN   A OE1 1 
ATOM   1407 N NE2 . GLN   A 1 219 ? -37.841 -38.752 -24.209 1.00 81.88  ? 592 GLN   A NE2 1 
ATOM   1408 N N   . GLN   A 1 220 ? -41.236 -33.533 -25.933 1.00 47.36  ? 593 GLN   A N   1 
ATOM   1409 C CA  . GLN   A 1 220 ? -42.213 -32.987 -26.853 1.00 51.14  ? 593 GLN   A CA  1 
ATOM   1410 C C   . GLN   A 1 220 ? -42.086 -31.463 -26.982 1.00 50.96  ? 593 GLN   A C   1 
ATOM   1411 O O   . GLN   A 1 220 ? -42.680 -30.876 -27.889 1.00 50.26  ? 593 GLN   A O   1 
ATOM   1412 C CB  . GLN   A 1 220 ? -43.588 -33.317 -26.288 1.00 57.72  ? 593 GLN   A CB  1 
ATOM   1413 C CG  . GLN   A 1 220 ? -43.885 -34.809 -26.218 1.00 67.68  ? 593 GLN   A CG  1 
ATOM   1414 C CD  . GLN   A 1 220 ? -44.485 -35.338 -27.501 1.00 75.75  ? 593 GLN   A CD  1 
ATOM   1415 O OE1 . GLN   A 1 220 ? -43.848 -35.332 -28.559 1.00 79.22  ? 593 GLN   A OE1 1 
ATOM   1416 N NE2 . GLN   A 1 220 ? -45.739 -35.763 -27.422 1.00 80.72  ? 593 GLN   A NE2 1 
ATOM   1417 N N   . HIS   A 1 221 ? -41.371 -30.826 -26.031 1.00 46.15  ? 594 HIS   A N   1 
ATOM   1418 C CA  . HIS   A 1 221 ? -41.211 -29.376 -25.987 1.00 44.52  ? 594 HIS   A CA  1 
ATOM   1419 C C   . HIS   A 1 221 ? -42.583 -28.709 -25.885 1.00 46.75  ? 594 HIS   A C   1 
ATOM   1420 O O   . HIS   A 1 221 ? -42.943 -27.872 -26.713 1.00 46.00  ? 594 HIS   A O   1 
ATOM   1421 C CB  . HIS   A 1 221 ? -40.393 -28.869 -27.194 1.00 42.98  ? 594 HIS   A CB  1 
ATOM   1422 C CG  . HIS   A 1 221 ? -39.082 -29.553 -27.406 1.00 40.27  ? 594 HIS   A CG  1 
ATOM   1423 N ND1 . HIS   A 1 221 ? -38.025 -29.395 -26.532 1.00 39.43  ? 594 HIS   A ND1 1 
ATOM   1424 C CD2 . HIS   A 1 221 ? -38.641 -30.352 -28.357 1.00 41.57  ? 594 HIS   A CD2 1 
ATOM   1425 C CE1 . HIS   A 1 221 ? -36.994 -30.108 -26.947 1.00 39.17  ? 594 HIS   A CE1 1 
ATOM   1426 N NE2 . HIS   A 1 221 ? -37.342 -30.694 -28.058 1.00 43.05  ? 594 HIS   A NE2 1 
ATOM   1427 N N   . GLU   A 1 222 ? -43.343 -29.069 -24.848 1.00 49.25  ? 595 GLU   A N   1 
ATOM   1428 C CA  . GLU   A 1 222 ? -44.616 -28.411 -24.582 1.00 50.39  ? 595 GLU   A CA  1 
ATOM   1429 C C   . GLU   A 1 222 ? -44.868 -28.342 -23.086 1.00 44.11  ? 595 GLU   A C   1 
ATOM   1430 O O   . GLU   A 1 222 ? -44.188 -29.002 -22.306 1.00 43.87  ? 595 GLU   A O   1 
ATOM   1431 C CB  . GLU   A 1 222 ? -45.805 -29.102 -25.242 1.00 53.72  ? 595 GLU   A CB  1 
ATOM   1432 C CG  . GLU   A 1 222 ? -46.001 -30.546 -24.809 1.00 59.83  ? 595 GLU   A CG  1 
ATOM   1433 C CD  . GLU   A 1 222 ? -46.997 -31.310 -25.682 1.00 69.65  ? 595 GLU   A CD  1 
ATOM   1434 O OE1 . GLU   A 1 222 ? -47.667 -30.679 -26.532 1.00 74.35  ? 595 GLU   A OE1 1 
ATOM   1435 O OE2 . GLU   A 1 222 ? -47.072 -32.547 -25.537 1.00 73.36  ? 595 GLU   A OE2 1 
ATOM   1436 N N   . CYS   A 1 223 ? -45.843 -27.516 -22.721 1.00 42.41  ? 596 CYS   A N   1 
ATOM   1437 C CA  . CYS   A 1 223 ? -46.291 -27.378 -21.350 1.00 43.49  ? 596 CYS   A CA  1 
ATOM   1438 C C   . CYS   A 1 223 ? -47.167 -28.564 -20.995 1.00 41.87  ? 596 CYS   A C   1 
ATOM   1439 O O   . CYS   A 1 223 ? -48.222 -28.719 -21.562 1.00 42.40  ? 596 CYS   A O   1 
ATOM   1440 C CB  . CYS   A 1 223 ? -47.071 -26.088 -21.128 1.00 42.62  ? 596 CYS   A CB  1 
ATOM   1441 S SG  . CYS   A 1 223 ? -47.453 -25.799 -19.378 1.00 42.61  ? 596 CYS   A SG  1 
ATOM   1442 N N   . ALA   A 1 224 ? -46.691 -29.431 -20.088 1.00 41.94  ? 597 ALA   A N   1 
ATOM   1443 C CA  . ALA   A 1 224 ? -47.470 -30.607 -19.698 1.00 42.10  ? 597 ALA   A CA  1 
ATOM   1444 C C   . ALA   A 1 224 ? -48.569 -30.226 -18.705 1.00 42.25  ? 597 ALA   A C   1 
ATOM   1445 O O   . ALA   A 1 224 ? -49.571 -30.885 -18.642 1.00 42.54  ? 597 ALA   A O   1 
ATOM   1446 C CB  . ALA   A 1 224 ? -46.563 -31.665 -19.133 1.00 41.18  ? 597 ALA   A CB  1 
ATOM   1447 N N   . MET   A 1 225 ? -48.405 -29.093 -18.007 1.00 43.79  ? 598 MET   A N   1 
ATOM   1448 C CA  . MET   A 1 225 ? -49.158 -28.800 -16.811 1.00 45.04  ? 598 MET   A CA  1 
ATOM   1449 C C   . MET   A 1 225 ? -48.831 -27.376 -16.388 1.00 40.45  ? 598 MET   A C   1 
ATOM   1450 O O   . MET   A 1 225 ? -47.665 -26.984 -16.333 1.00 37.06  ? 598 MET   A O   1 
ATOM   1451 C CB  . MET   A 1 225 ? -48.681 -29.742 -15.703 1.00 53.16  ? 598 MET   A CB  1 
ATOM   1452 C CG  . MET   A 1 225 ? -49.700 -30.195 -14.710 1.00 60.76  ? 598 MET   A CG  1 
ATOM   1453 S SD  . MET   A 1 225 ? -48.972 -31.544 -13.748 1.00 65.06  ? 598 MET   A SD  1 
ATOM   1454 C CE  . MET   A 1 225 ? -49.011 -32.830 -15.009 1.00 72.63  ? 598 MET   A CE  1 
ATOM   1455 N N   . SER   A 1 226 ? -49.844 -26.630 -15.975 1.00 42.95  ? 599 SER   A N   1 
ATOM   1456 C CA  . SER   A 1 226 ? -49.603 -25.362 -15.295 1.00 42.21  ? 599 SER   A CA  1 
ATOM   1457 C C   . SER   A 1 226 ? -50.761 -25.060 -14.362 1.00 40.53  ? 599 SER   A C   1 
ATOM   1458 O O   . SER   A 1 226 ? -51.874 -25.492 -14.619 1.00 41.31  ? 599 SER   A O   1 
ATOM   1459 C CB  . SER   A 1 226 ? -49.440 -24.227 -16.284 1.00 40.03  ? 599 SER   A CB  1 
ATOM   1460 O OG  . SER   A 1 226 ? -50.638 -24.109 -17.034 1.00 42.04  ? 599 SER   A OG  1 
ATOM   1461 N N   . TRP   A 1 227 ? -50.498 -24.189 -13.386 1.00 40.02  ? 600 TRP   A N   1 
ATOM   1462 C CA  . TRP   A 1 227 ? -51.482 -23.822 -12.394 1.00 43.91  ? 600 TRP   A CA  1 
ATOM   1463 C C   . TRP   A 1 227 ? -51.017 -22.575 -11.645 1.00 44.35  ? 600 TRP   A C   1 
ATOM   1464 O O   . TRP   A 1 227 ? -49.825 -22.306 -11.550 1.00 43.44  ? 600 TRP   A O   1 
ATOM   1465 C CB  . TRP   A 1 227 ? -51.711 -24.995 -11.418 1.00 42.61  ? 600 TRP   A CB  1 
ATOM   1466 C CG  . TRP   A 1 227 ? -50.511 -25.354 -10.569 1.00 39.33  ? 600 TRP   A CG  1 
ATOM   1467 C CD1 . TRP   A 1 227 ? -50.238 -24.853 -9.330  1.00 40.88  ? 600 TRP   A CD1 1 
ATOM   1468 C CD2 . TRP   A 1 227 ? -49.462 -26.309 -10.846 1.00 37.22  ? 600 TRP   A CD2 1 
ATOM   1469 N NE1 . TRP   A 1 227 ? -49.094 -25.416 -8.822  1.00 39.98  ? 600 TRP   A NE1 1 
ATOM   1470 C CE2 . TRP   A 1 227 ? -48.590 -26.306 -9.730  1.00 37.44  ? 600 TRP   A CE2 1 
ATOM   1471 C CE3 . TRP   A 1 227 ? -49.163 -27.164 -11.913 1.00 39.74  ? 600 TRP   A CE3 1 
ATOM   1472 C CZ2 . TRP   A 1 227 ? -47.443 -27.105 -9.661  1.00 36.16  ? 600 TRP   A CZ2 1 
ATOM   1473 C CZ3 . TRP   A 1 227 ? -48.020 -27.946 -11.854 1.00 36.69  ? 600 TRP   A CZ3 1 
ATOM   1474 C CH2 . TRP   A 1 227 ? -47.181 -27.929 -10.732 1.00 35.98  ? 600 TRP   A CH2 1 
ATOM   1475 N N   . ARG   A 1 228 ? -51.982 -21.894 -11.035 1.00 47.08  ? 601 ARG   A N   1 
ATOM   1476 C CA  . ARG   A 1 228 ? -51.726 -20.754 -10.183 1.00 51.00  ? 601 ARG   A CA  1 
ATOM   1477 C C   . ARG   A 1 228 ? -51.196 -21.260 -8.838  1.00 46.46  ? 601 ARG   A C   1 
ATOM   1478 O O   . ARG   A 1 228 ? -51.857 -22.035 -8.154  1.00 46.17  ? 601 ARG   A O   1 
ATOM   1479 C CB  . ARG   A 1 228 ? -53.052 -19.982 -10.121 1.00 60.65  ? 601 ARG   A CB  1 
ATOM   1480 C CG  . ARG   A 1 228 ? -53.017 -18.697 -9.305  1.00 73.62  ? 601 ARG   A CG  1 
ATOM   1481 C CD  . ARG   A 1 228 ? -52.469 -17.468 -10.041 1.00 82.75  ? 601 ARG   A CD  1 
ATOM   1482 N NE  . ARG   A 1 228 ? -52.163 -16.423 -9.054  1.00 92.05  ? 601 ARG   A NE  1 
ATOM   1483 C CZ  . ARG   A 1 228 ? -52.877 -15.325 -8.823  1.00 98.06  ? 601 ARG   A CZ  1 
ATOM   1484 N NH1 . ARG   A 1 228 ? -52.596 -14.575 -7.778  1.00 103.69 ? 601 ARG   A NH1 1 
ATOM   1485 N NH2 . ARG   A 1 228 ? -53.893 -15.002 -9.604  1.00 99.13  ? 601 ARG   A NH2 1 
ATOM   1486 N N   . ALA   A 1 229 ? -49.992 -20.818 -8.463  1.00 43.39  ? 602 ALA   A N   1 
ATOM   1487 C CA  . ALA   A 1 229 ? -49.301 -21.386 -7.321  1.00 41.87  ? 602 ALA   A CA  1 
ATOM   1488 C C   . ALA   A 1 229 ? -49.244 -20.409 -6.147  1.00 41.89  ? 602 ALA   A C   1 
ATOM   1489 O O   . ALA   A 1 229 ? -49.253 -20.854 -5.016  1.00 39.63  ? 602 ALA   A O   1 
ATOM   1490 C CB  . ALA   A 1 229 ? -47.917 -21.812 -7.715  1.00 39.95  ? 602 ALA   A CB  1 
ATOM   1491 N N   . HIS   A 1 230 ? -49.020 -19.124 -6.432  1.00 39.63  ? 603 HIS   A N   1 
ATOM   1492 C CA  . HIS   A 1 230 ? -48.831 -18.116 -5.408  1.00 41.97  ? 603 HIS   A CA  1 
ATOM   1493 C C   . HIS   A 1 230 ? -49.616 -16.860 -5.779  1.00 44.67  ? 603 HIS   A C   1 
ATOM   1494 O O   . HIS   A 1 230 ? -49.907 -16.605 -6.943  1.00 41.68  ? 603 HIS   A O   1 
ATOM   1495 C CB  . HIS   A 1 230 ? -47.347 -17.815 -5.192  1.00 39.83  ? 603 HIS   A CB  1 
ATOM   1496 C CG  . HIS   A 1 230 ? -46.573 -18.958 -4.634  1.00 40.36  ? 603 HIS   A CG  1 
ATOM   1497 N ND1 . HIS   A 1 230 ? -46.376 -19.138 -3.281  1.00 40.97  ? 603 HIS   A ND1 1 
ATOM   1498 C CD2 . HIS   A 1 230 ? -45.949 -19.988 -5.237  1.00 38.52  ? 603 HIS   A CD2 1 
ATOM   1499 C CE1 . HIS   A 1 230 ? -45.688 -20.268 -3.091  1.00 38.93  ? 603 HIS   A CE1 1 
ATOM   1500 N NE2 . HIS   A 1 230 ? -45.384 -20.773 -4.262  1.00 36.92  ? 603 HIS   A NE2 1 
ATOM   1501 N N   . TYR   A 1 231 ? -50.030 -16.133 -4.751  1.00 47.88  ? 604 TYR   A N   1 
ATOM   1502 C CA  . TYR   A 1 231 ? -50.431 -14.748 -4.901  1.00 55.23  ? 604 TYR   A CA  1 
ATOM   1503 C C   . TYR   A 1 231 ? -49.156 -13.912 -4.920  1.00 50.44  ? 604 TYR   A C   1 
ATOM   1504 O O   . TYR   A 1 231 ? -48.496 -13.757 -3.897  1.00 52.78  ? 604 TYR   A O   1 
ATOM   1505 C CB  . TYR   A 1 231 ? -51.381 -14.348 -3.770  1.00 62.95  ? 604 TYR   A CB  1 
ATOM   1506 C CG  . TYR   A 1 231 ? -51.968 -12.954 -3.934  1.00 81.54  ? 604 TYR   A CG  1 
ATOM   1507 C CD1 . TYR   A 1 231 ? -52.951 -12.703 -4.891  1.00 94.23  ? 604 TYR   A CD1 1 
ATOM   1508 C CD2 . TYR   A 1 231 ? -51.557 -11.891 -3.129  1.00 86.46  ? 604 TYR   A CD2 1 
ATOM   1509 C CE1 . TYR   A 1 231 ? -53.500 -11.440 -5.047  1.00 97.53  ? 604 TYR   A CE1 1 
ATOM   1510 C CE2 . TYR   A 1 231 ? -52.090 -10.621 -3.285  1.00 90.12  ? 604 TYR   A CE2 1 
ATOM   1511 C CZ  . TYR   A 1 231 ? -53.065 -10.399 -4.245  1.00 98.72  ? 604 TYR   A CZ  1 
ATOM   1512 O OH  . TYR   A 1 231 ? -53.610 -9.163  -4.409  1.00 109.40 ? 604 TYR   A OH  1 
ATOM   1513 N N   . GLY   A 1 232 ? -48.791 -13.443 -6.107  1.00 45.31  ? 605 GLY   A N   1 
ATOM   1514 C CA  . GLY   A 1 232 ? -47.528 -12.772 -6.326  1.00 42.94  ? 605 GLY   A CA  1 
ATOM   1515 C C   . GLY   A 1 232 ? -46.552 -13.729 -6.980  1.00 42.15  ? 605 GLY   A C   1 
ATOM   1516 O O   . GLY   A 1 232 ? -46.917 -14.842 -7.332  1.00 43.47  ? 605 GLY   A O   1 
ATOM   1517 N N   . GLU   A 1 233 ? -45.288 -13.334 -7.006  1.00 41.91  ? 606 GLU   A N   1 
ATOM   1518 C CA  . GLU   A 1 233 ? -44.279 -14.046 -7.757  1.00 41.30  ? 606 GLU   A CA  1 
ATOM   1519 C C   . GLU   A 1 233 ? -43.954 -15.384 -7.105  1.00 40.69  ? 606 GLU   A C   1 
ATOM   1520 O O   . GLU   A 1 233 ? -43.996 -15.534 -5.886  1.00 38.81  ? 606 GLU   A O   1 
ATOM   1521 C CB  . GLU   A 1 233 ? -43.001 -13.213 -7.838  1.00 43.43  ? 606 GLU   A CB  1 
ATOM   1522 C CG  . GLU   A 1 233 ? -43.225 -11.818 -8.431  1.00 45.79  ? 606 GLU   A CG  1 
ATOM   1523 C CD  . GLU   A 1 233 ? -41.928 -11.158 -8.888  1.00 47.10  ? 606 GLU   A CD  1 
ATOM   1524 O OE1 . GLU   A 1 233 ? -41.149 -11.811 -9.625  1.00 46.94  ? 606 GLU   A OE1 1 
ATOM   1525 O OE2 . GLU   A 1 233 ? -41.679 -10.010 -8.495  1.00 54.02  ? 606 GLU   A OE2 1 
ATOM   1526 N N   . VAL   A 1 234 ? -43.516 -16.317 -7.957  1.00 37.97  ? 607 VAL   A N   1 
ATOM   1527 C CA  . VAL   A 1 234 ? -42.861 -17.531 -7.532  1.00 33.12  ? 607 VAL   A CA  1 
ATOM   1528 C C   . VAL   A 1 234 ? -41.362 -17.294 -7.555  1.00 32.89  ? 607 VAL   A C   1 
ATOM   1529 O O   . VAL   A 1 234 ? -40.853 -16.768 -8.521  1.00 34.27  ? 607 VAL   A O   1 
ATOM   1530 C CB  . VAL   A 1 234 ? -43.255 -18.701 -8.452  1.00 32.65  ? 607 VAL   A CB  1 
ATOM   1531 C CG1 . VAL   A 1 234 ? -42.778 -20.031 -7.893  1.00 32.28  ? 607 VAL   A CG1 1 
ATOM   1532 C CG2 . VAL   A 1 234 ? -44.758 -18.737 -8.719  1.00 33.29  ? 607 VAL   A CG2 1 
ATOM   1533 N N   . TYR   A 1 235 ? -40.659 -17.723 -6.497  1.00 33.66  ? 608 TYR   A N   1 
ATOM   1534 C CA  . TYR   A 1 235 ? -39.255 -17.408 -6.336  1.00 35.27  ? 608 TYR   A CA  1 
ATOM   1535 C C   . TYR   A 1 235 ? -38.357 -18.629 -6.543  1.00 34.10  ? 608 TYR   A C   1 
ATOM   1536 O O   . TYR   A 1 235 ? -37.237 -18.494 -7.016  1.00 36.33  ? 608 TYR   A O   1 
ATOM   1537 C CB  . TYR   A 1 235 ? -39.072 -16.858 -4.932  1.00 39.15  ? 608 TYR   A CB  1 
ATOM   1538 C CG  . TYR   A 1 235 ? -39.711 -15.512 -4.662  1.00 41.49  ? 608 TYR   A CG  1 
ATOM   1539 C CD1 . TYR   A 1 235 ? -39.710 -14.495 -5.618  1.00 41.67  ? 608 TYR   A CD1 1 
ATOM   1540 C CD2 . TYR   A 1 235 ? -40.221 -15.223 -3.405  1.00 45.89  ? 608 TYR   A CD2 1 
ATOM   1541 C CE1 . TYR   A 1 235 ? -40.212 -13.235 -5.326  1.00 44.04  ? 608 TYR   A CE1 1 
ATOM   1542 C CE2 . TYR   A 1 235 ? -40.735 -13.968 -3.104  1.00 51.15  ? 608 TYR   A CE2 1 
ATOM   1543 C CZ  . TYR   A 1 235 ? -40.726 -12.970 -4.064  1.00 47.80  ? 608 TYR   A CZ  1 
ATOM   1544 O OH  . TYR   A 1 235 ? -41.256 -11.752 -3.761  1.00 52.53  ? 608 TYR   A OH  1 
ATOM   1545 N N   . SER   A 1 236 ? -38.803 -19.799 -6.074  1.00 34.53  ? 609 SER   A N   1 
ATOM   1546 C CA  . SER   A 1 236 ? -38.046 -21.022 -6.237  1.00 32.91  ? 609 SER   A CA  1 
ATOM   1547 C C   . SER   A 1 236 ? -39.012 -22.189 -6.403  1.00 33.60  ? 609 SER   A C   1 
ATOM   1548 O O   . SER   A 1 236 ? -40.121 -22.171 -5.871  1.00 34.59  ? 609 SER   A O   1 
ATOM   1549 C CB  . SER   A 1 236 ? -37.077 -21.277 -5.086  1.00 35.13  ? 609 SER   A CB  1 
ATOM   1550 O OG  . SER   A 1 236 ? -36.087 -20.268 -4.964  1.00 38.31  ? 609 SER   A OG  1 
ATOM   1551 N N   . VAL   A 1 237 ? -38.544 -23.204 -7.142  1.00 34.07  ? 610 VAL   A N   1 
ATOM   1552 C CA  . VAL   A 1 237 ? -39.278 -24.427 -7.434  1.00 36.17  ? 610 VAL   A CA  1 
ATOM   1553 C C   . VAL   A 1 237 ? -38.277 -25.585 -7.423  1.00 35.94  ? 610 VAL   A C   1 
ATOM   1554 O O   . VAL   A 1 237 ? -37.114 -25.403 -7.788  1.00 33.52  ? 610 VAL   A O   1 
ATOM   1555 C CB  . VAL   A 1 237 ? -39.981 -24.370 -8.797  1.00 36.13  ? 610 VAL   A CB  1 
ATOM   1556 C CG1 . VAL   A 1 237 ? -41.158 -23.408 -8.798  1.00 37.69  ? 610 VAL   A CG1 1 
ATOM   1557 C CG2 . VAL   A 1 237 ? -38.987 -24.025 -9.910  1.00 36.73  ? 610 VAL   A CG2 1 
ATOM   1558 N N   . GLU   A 1 238 ? -38.735 -26.772 -7.011  1.00 35.20  ? 611 GLU   A N   1 
ATOM   1559 C CA  . GLU   A 1 238 ? -37.878 -27.938 -7.025  1.00 38.58  ? 611 GLU   A CA  1 
ATOM   1560 C C   . GLU   A 1 238 ? -38.751 -29.186 -7.119  1.00 38.98  ? 611 GLU   A C   1 
ATOM   1561 O O   . GLU   A 1 238 ? -39.870 -29.198 -6.598  1.00 40.17  ? 611 GLU   A O   1 
ATOM   1562 C CB  . GLU   A 1 238 ? -36.960 -27.940 -5.793  1.00 44.40  ? 611 GLU   A CB  1 
ATOM   1563 C CG  . GLU   A 1 238 ? -35.983 -29.126 -5.773  1.00 53.74  ? 611 GLU   A CG  1 
ATOM   1564 C CD  . GLU   A 1 238 ? -35.020 -29.156 -6.966  1.00 65.30  ? 611 GLU   A CD  1 
ATOM   1565 O OE1 . GLU   A 1 238 ? -34.116 -28.299 -6.834  1.00 63.70  ? 611 GLU   A OE1 1 
ATOM   1566 O OE2 . GLU   A 1 238 ? -35.187 -29.908 -8.036  1.00 54.34  ? 611 GLU   A OE2 1 
ATOM   1567 N N   . PHE   A 1 239 ? -38.213 -30.234 -7.771  1.00 37.16  ? 612 PHE   A N   1 
ATOM   1568 C CA  . PHE   A 1 239 ? -38.769 -31.580 -7.700  1.00 36.92  ? 612 PHE   A CA  1 
ATOM   1569 C C   . PHE   A 1 239 ? -38.425 -32.202 -6.346  1.00 39.46  ? 612 PHE   A C   1 
ATOM   1570 O O   . PHE   A 1 239 ? -37.311 -32.029 -5.853  1.00 41.22  ? 612 PHE   A O   1 
ATOM   1571 C CB  . PHE   A 1 239 ? -38.228 -32.439 -8.844  1.00 36.72  ? 612 PHE   A CB  1 
ATOM   1572 C CG  . PHE   A 1 239 ? -38.800 -32.051 -10.202 1.00 35.13  ? 612 PHE   A CG  1 
ATOM   1573 C CD1 . PHE   A 1 239 ? -38.199 -31.066 -10.977 1.00 34.51  ? 612 PHE   A CD1 1 
ATOM   1574 C CD2 . PHE   A 1 239 ? -39.958 -32.644 -10.677 1.00 33.98  ? 612 PHE   A CD2 1 
ATOM   1575 C CE1 . PHE   A 1 239 ? -38.741 -30.700 -12.209 1.00 35.38  ? 612 PHE   A CE1 1 
ATOM   1576 C CE2 . PHE   A 1 239 ? -40.514 -32.242 -11.881 1.00 35.42  ? 612 PHE   A CE2 1 
ATOM   1577 C CZ  . PHE   A 1 239 ? -39.896 -31.279 -12.652 1.00 33.59  ? 612 PHE   A CZ  1 
ATOM   1578 N N   . SER   A 1 240 ? -39.428 -32.837 -5.711  1.00 39.22  ? 613 SER   A N   1 
ATOM   1579 C CA  . SER   A 1 240 ? -39.176 -33.797 -4.655  1.00 40.60  ? 613 SER   A CA  1 
ATOM   1580 C C   . SER   A 1 240 ? -38.229 -34.875 -5.182  1.00 43.69  ? 613 SER   A C   1 
ATOM   1581 O O   . SER   A 1 240 ? -38.218 -35.183 -6.366  1.00 42.25  ? 613 SER   A O   1 
ATOM   1582 C CB  . SER   A 1 240 ? -40.455 -34.435 -4.138  1.00 39.48  ? 613 SER   A CB  1 
ATOM   1583 O OG  . SER   A 1 240 ? -40.960 -35.415 -5.048  1.00 38.75  ? 613 SER   A OG  1 
ATOM   1584 N N   . TYR   A 1 241 ? -37.530 -35.518 -4.260  1.00 47.53  ? 614 TYR   A N   1 
ATOM   1585 C CA  . TYR   A 1 241 ? -36.660 -36.622 -4.589  1.00 48.24  ? 614 TYR   A CA  1 
ATOM   1586 C C   . TYR   A 1 241 ? -37.418 -37.685 -5.374  1.00 46.76  ? 614 TYR   A C   1 
ATOM   1587 O O   . TYR   A 1 241 ? -36.869 -38.232 -6.315  1.00 47.60  ? 614 TYR   A O   1 
ATOM   1588 C CB  . TYR   A 1 241 ? -36.058 -37.152 -3.286  1.00 52.06  ? 614 TYR   A CB  1 
ATOM   1589 C CG  . TYR   A 1 241 ? -35.043 -38.248 -3.543  1.00 59.11  ? 614 TYR   A CG  1 
ATOM   1590 C CD1 . TYR   A 1 241 ? -33.826 -37.958 -4.141  1.00 61.77  ? 614 TYR   A CD1 1 
ATOM   1591 C CD2 . TYR   A 1 241 ? -35.340 -39.575 -3.270  1.00 63.03  ? 614 TYR   A CD2 1 
ATOM   1592 C CE1 . TYR   A 1 241 ? -32.901 -38.954 -4.399  1.00 64.50  ? 614 TYR   A CE1 1 
ATOM   1593 C CE2 . TYR   A 1 241 ? -34.427 -40.582 -3.525  1.00 71.50  ? 614 TYR   A CE2 1 
ATOM   1594 C CZ  . TYR   A 1 241 ? -33.204 -40.266 -4.094  1.00 70.32  ? 614 TYR   A CZ  1 
ATOM   1595 O OH  . TYR   A 1 241 ? -32.296 -41.248 -4.347  1.00 74.41  ? 614 TYR   A OH  1 
ATOM   1596 N N   . ASP   A 1 242 ? -38.649 -38.028 -4.954  1.00 48.31  ? 615 ASP   A N   1 
ATOM   1597 C CA  . ASP   A 1 242 ? -39.387 -39.115 -5.601  1.00 49.64  ? 615 ASP   A CA  1 
ATOM   1598 C C   . ASP   A 1 242 ? -40.085 -38.616 -6.873  1.00 45.73  ? 615 ASP   A C   1 
ATOM   1599 O O   . ASP   A 1 242 ? -40.623 -39.423 -7.622  1.00 46.67  ? 615 ASP   A O   1 
ATOM   1600 C CB  . ASP   A 1 242 ? -40.343 -39.854 -4.653  1.00 53.79  ? 615 ASP   A CB  1 
ATOM   1601 C CG  . ASP   A 1 242 ? -41.590 -39.113 -4.171  1.00 52.40  ? 615 ASP   A CG  1 
ATOM   1602 O OD1 . ASP   A 1 242 ? -41.679 -37.905 -4.368  1.00 51.41  ? 615 ASP   A OD1 1 
ATOM   1603 O OD2 . ASP   A 1 242 ? -42.479 -39.769 -3.615  1.00 62.69  ? 615 ASP   A OD2 1 
ATOM   1604 N N   . GLU   A 1 243 ? -40.118 -37.294 -7.068  1.00 42.92  ? 616 GLU   A N   1 
ATOM   1605 C CA  . GLU   A 1 243 ? -40.646 -36.682 -8.280  1.00 44.65  ? 616 GLU   A CA  1 
ATOM   1606 C C   . GLU   A 1 243 ? -42.148 -36.908 -8.373  1.00 43.80  ? 616 GLU   A C   1 
ATOM   1607 O O   . GLU   A 1 243 ? -42.733 -36.721 -9.421  1.00 43.98  ? 616 GLU   A O   1 
ATOM   1608 C CB  . GLU   A 1 243 ? -39.896 -37.110 -9.550  1.00 46.96  ? 616 GLU   A CB  1 
ATOM   1609 C CG  . GLU   A 1 243 ? -38.404 -36.775 -9.457  1.00 48.60  ? 616 GLU   A CG  1 
ATOM   1610 C CD  . GLU   A 1 243 ? -37.532 -36.823 -10.710 1.00 46.32  ? 616 GLU   A CD  1 
ATOM   1611 O OE1 . GLU   A 1 243 ? -37.954 -37.390 -11.738 1.00 43.00  ? 616 GLU   A OE1 1 
ATOM   1612 O OE2 . GLU   A 1 243 ? -36.411 -36.216 -10.637 1.00 47.34  ? 616 GLU   A OE2 1 
ATOM   1613 N N   . ASN   A 1 244 ? -42.792 -37.196 -7.241  1.00 46.46  ? 617 ASN   A N   1 
ATOM   1614 C CA  . ASN   A 1 244 ? -44.247 -37.181 -7.197  1.00 45.75  ? 617 ASN   A CA  1 
ATOM   1615 C C   . ASN   A 1 244 ? -44.765 -35.763 -6.933  1.00 44.77  ? 617 ASN   A C   1 
ATOM   1616 O O   . ASN   A 1 244 ? -45.923 -35.487 -7.209  1.00 49.71  ? 617 ASN   A O   1 
ATOM   1617 C CB  . ASN   A 1 244 ? -44.770 -38.180 -6.200  1.00 46.72  ? 617 ASN   A CB  1 
ATOM   1618 C CG  . ASN   A 1 244 ? -44.473 -39.585 -6.661  1.00 49.10  ? 617 ASN   A CG  1 
ATOM   1619 O OD1 . ASN   A 1 244 ? -44.864 -39.970 -7.772  1.00 49.44  ? 617 ASN   A OD1 1 
ATOM   1620 N ND2 . ASN   A 1 244 ? -43.812 -40.362 -5.820  1.00 50.11  ? 617 ASN   A ND2 1 
ATOM   1621 N N   . THR   A 1 245 ? -43.911 -34.862 -6.446  1.00 39.66  ? 618 THR   A N   1 
ATOM   1622 C CA  . THR   A 1 245 ? -44.362 -33.519 -6.139  1.00 40.02  ? 618 THR   A CA  1 
ATOM   1623 C C   . THR   A 1 245 ? -43.331 -32.514 -6.605  1.00 38.45  ? 618 THR   A C   1 
ATOM   1624 O O   . THR   A 1 245 ? -42.172 -32.845 -6.864  1.00 38.94  ? 618 THR   A O   1 
ATOM   1625 C CB  . THR   A 1 245 ? -44.653 -33.344 -4.641  1.00 41.81  ? 618 THR   A CB  1 
ATOM   1626 O OG1 . THR   A 1 245 ? -43.499 -33.676 -3.870  1.00 40.61  ? 618 THR   A OG1 1 
ATOM   1627 C CG2 . THR   A 1 245 ? -45.800 -34.225 -4.179  1.00 43.17  ? 618 THR   A CG2 1 
ATOM   1628 N N   . VAL   A 1 246 ? -43.771 -31.272 -6.662  1.00 38.30  ? 619 VAL   A N   1 
ATOM   1629 C CA  . VAL   A 1 246 ? -42.854 -30.162 -6.729  1.00 37.16  ? 619 VAL   A CA  1 
ATOM   1630 C C   . VAL   A 1 246 ? -43.140 -29.261 -5.550  1.00 37.14  ? 619 VAL   A C   1 
ATOM   1631 O O   . VAL   A 1 246 ? -44.273 -29.187 -5.083  1.00 37.41  ? 619 VAL   A O   1 
ATOM   1632 C CB  . VAL   A 1 246 ? -42.948 -29.388 -8.061  1.00 38.14  ? 619 VAL   A CB  1 
ATOM   1633 C CG1 . VAL   A 1 246 ? -42.568 -30.265 -9.270  1.00 42.89  ? 619 VAL   A CG1 1 
ATOM   1634 C CG2 . VAL   A 1 246 ? -44.320 -28.813 -8.270  1.00 37.21  ? 619 VAL   A CG2 1 
ATOM   1635 N N   . TYR   A 1 247 ? -42.095 -28.549 -5.125  1.00 37.59  ? 620 TYR   A N   1 
ATOM   1636 C CA  . TYR   A 1 247 ? -42.191 -27.584 -4.052  1.00 39.53  ? 620 TYR   A CA  1 
ATOM   1637 C C   . TYR   A 1 247 ? -42.002 -26.194 -4.639  1.00 36.46  ? 620 TYR   A C   1 
ATOM   1638 O O   . TYR   A 1 247 ? -41.143 -25.994 -5.485  1.00 33.92  ? 620 TYR   A O   1 
ATOM   1639 C CB  . TYR   A 1 247 ? -41.125 -27.819 -2.971  1.00 39.37  ? 620 TYR   A CB  1 
ATOM   1640 C CG  . TYR   A 1 247 ? -41.064 -29.214 -2.336  1.00 43.60  ? 620 TYR   A CG  1 
ATOM   1641 C CD1 . TYR   A 1 247 ? -41.970 -29.621 -1.384  1.00 50.08  ? 620 TYR   A CD1 1 
ATOM   1642 C CD2 . TYR   A 1 247 ? -40.003 -30.068 -2.603  1.00 48.23  ? 620 TYR   A CD2 1 
ATOM   1643 C CE1 . TYR   A 1 247 ? -41.870 -30.866 -0.769  1.00 56.30  ? 620 TYR   A CE1 1 
ATOM   1644 C CE2 . TYR   A 1 247 ? -39.902 -31.315 -2.017  1.00 50.06  ? 620 TYR   A CE2 1 
ATOM   1645 C CZ  . TYR   A 1 247 ? -40.845 -31.720 -1.113  1.00 51.12  ? 620 TYR   A CZ  1 
ATOM   1646 O OH  . TYR   A 1 247 ? -40.712 -32.951 -0.554  1.00 77.11  ? 620 TYR   A OH  1 
ATOM   1647 N N   . SER   A 1 248 ? -42.707 -25.216 -4.079  1.00 36.58  ? 621 SER   A N   1 
ATOM   1648 C CA  . SER   A 1 248 ? -42.501 -23.827 -4.454  1.00 35.14  ? 621 SER   A CA  1 
ATOM   1649 C C   . SER   A 1 248 ? -42.482 -22.935 -3.221  1.00 35.57  ? 621 SER   A C   1 
ATOM   1650 O O   . SER   A 1 248 ? -43.071 -23.233 -2.174  1.00 35.92  ? 621 SER   A O   1 
ATOM   1651 C CB  . SER   A 1 248 ? -43.551 -23.358 -5.436  1.00 32.80  ? 621 SER   A CB  1 
ATOM   1652 O OG  . SER   A 1 248 ? -44.811 -23.302 -4.790  1.00 33.31  ? 621 SER   A OG  1 
ATOM   1653 N N   . ILE   A 1 249 ? -41.834 -21.797 -3.393  1.00 35.25  ? 622 ILE   A N   1 
ATOM   1654 C CA  . ILE   A 1 249 ? -41.908 -20.728 -2.427  1.00 36.52  ? 622 ILE   A CA  1 
ATOM   1655 C C   . ILE   A 1 249 ? -42.093 -19.417 -3.180  1.00 35.60  ? 622 ILE   A C   1 
ATOM   1656 O O   . ILE   A 1 249 ? -41.512 -19.227 -4.244  1.00 34.96  ? 622 ILE   A O   1 
ATOM   1657 C CB  . ILE   A 1 249 ? -40.648 -20.759 -1.573  1.00 37.15  ? 622 ILE   A CB  1 
ATOM   1658 C CG1 . ILE   A 1 249 ? -40.730 -19.793 -0.430  1.00 40.16  ? 622 ILE   A CG1 1 
ATOM   1659 C CG2 . ILE   A 1 249 ? -39.418 -20.532 -2.442  1.00 39.60  ? 622 ILE   A CG2 1 
ATOM   1660 C CD1 . ILE   A 1 249 ? -39.622 -19.992 0.578   1.00 42.92  ? 622 ILE   A CD1 1 
ATOM   1661 N N   . GLY   A 1 250 ? -42.928 -18.527 -2.644  1.00 36.07  ? 623 GLY   A N   1 
ATOM   1662 C CA  . GLY   A 1 250 ? -43.247 -17.304 -3.358  1.00 38.41  ? 623 GLY   A CA  1 
ATOM   1663 C C   . GLY   A 1 250 ? -43.505 -16.116 -2.441  1.00 38.89  ? 623 GLY   A C   1 
ATOM   1664 O O   . GLY   A 1 250 ? -43.367 -16.204 -1.218  1.00 37.61  ? 623 GLY   A O   1 
ATOM   1665 N N   . GLU   A 1 251 ? -43.985 -15.042 -3.066  1.00 40.04  ? 624 GLU   A N   1 
ATOM   1666 C CA  . GLU   A 1 251 ? -44.064 -13.720 -2.456  1.00 41.36  ? 624 GLU   A CA  1 
ATOM   1667 C C   . GLU   A 1 251 ? -45.148 -13.645 -1.372  1.00 42.68  ? 624 GLU   A C   1 
ATOM   1668 O O   . GLU   A 1 251 ? -45.127 -12.726 -0.533  1.00 43.67  ? 624 GLU   A O   1 
ATOM   1669 C CB  . GLU   A 1 251 ? -44.347 -12.747 -3.603  1.00 43.51  ? 624 GLU   A CB  1 
ATOM   1670 C CG  . GLU   A 1 251 ? -44.431 -11.274 -3.184  1.00 47.28  ? 624 GLU   A CG  1 
ATOM   1671 C CD  . GLU   A 1 251 ? -44.736 -10.366 -4.373  1.00 49.39  ? 624 GLU   A CD  1 
ATOM   1672 O OE1 . GLU   A 1 251 ? -44.883 -10.851 -5.515  1.00 46.60  ? 624 GLU   A OE1 1 
ATOM   1673 O OE2 . GLU   A 1 251 ? -44.817 -9.162  -4.149  1.00 54.72  ? 624 GLU   A OE2 1 
ATOM   1674 N N   . ASP   A 1 252 ? -46.107 -14.590 -1.401  1.00 40.05  ? 625 ASP   A N   1 
ATOM   1675 C CA  . ASP   A 1 252 ? -47.180 -14.621 -0.420  1.00 41.30  ? 625 ASP   A CA  1 
ATOM   1676 C C   . ASP   A 1 252 ? -46.690 -15.236 0.883   1.00 42.44  ? 625 ASP   A C   1 
ATOM   1677 O O   . ASP   A 1 252 ? -47.465 -15.373 1.797   1.00 48.76  ? 625 ASP   A O   1 
ATOM   1678 C CB  . ASP   A 1 252 ? -48.422 -15.344 -0.924  1.00 40.84  ? 625 ASP   A CB  1 
ATOM   1679 C CG  . ASP   A 1 252 ? -48.207 -16.713 -1.568  1.00 40.56  ? 625 ASP   A CG  1 
ATOM   1680 O OD1 . ASP   A 1 252 ? -47.098 -17.314 -1.411  1.00 38.25  ? 625 ASP   A OD1 1 
ATOM   1681 O OD2 . ASP   A 1 252 ? -49.115 -17.147 -2.275  1.00 42.21  ? 625 ASP   A OD2 1 
ATOM   1682 N N   . GLY   A 1 253 ? -45.409 -15.611 0.973   1.00 45.36  ? 626 GLY   A N   1 
ATOM   1683 C CA  . GLY   A 1 253 ? -44.840 -16.127 2.220   1.00 44.25  ? 626 GLY   A CA  1 
ATOM   1684 C C   . GLY   A 1 253 ? -44.923 -17.661 2.357   1.00 43.62  ? 626 GLY   A C   1 
ATOM   1685 O O   . GLY   A 1 253 ? -44.422 -18.230 3.340   1.00 43.22  ? 626 GLY   A O   1 
ATOM   1686 N N   . LYS   A 1 254 ? -45.538 -18.324 1.375   1.00 42.07  ? 627 LYS   A N   1 
ATOM   1687 C CA  . LYS   A 1 254 ? -45.909 -19.724 1.508   1.00 46.36  ? 627 LYS   A CA  1 
ATOM   1688 C C   . LYS   A 1 254 ? -44.899 -20.655 0.839   1.00 42.11  ? 627 LYS   A C   1 
ATOM   1689 O O   . LYS   A 1 254 ? -44.349 -20.359 -0.218  1.00 40.22  ? 627 LYS   A O   1 
ATOM   1690 C CB  . LYS   A 1 254 ? -47.289 -19.966 0.904   1.00 52.83  ? 627 LYS   A CB  1 
ATOM   1691 C CG  . LYS   A 1 254 ? -48.371 -19.206 1.648   1.00 59.86  ? 627 LYS   A CG  1 
ATOM   1692 C CD  . LYS   A 1 254 ? -49.763 -19.435 1.083   1.00 69.11  ? 627 LYS   A CD  1 
ATOM   1693 C CE  . LYS   A 1 254 ? -50.806 -18.738 1.909   1.00 78.25  ? 627 LYS   A CE  1 
ATOM   1694 N NZ  . LYS   A 1 254 ? -52.071 -19.468 1.811   1.00 85.58  ? 627 LYS   A NZ  1 
ATOM   1695 N N   . PHE   A 1 255 ? -44.647 -21.762 1.532   1.00 41.43  ? 628 PHE   A N   1 
ATOM   1696 C CA  . PHE   A 1 255 ? -44.036 -22.964 1.006   1.00 39.49  ? 628 PHE   A CA  1 
ATOM   1697 C C   . PHE   A 1 255 ? -45.115 -24.007 0.742   1.00 39.71  ? 628 PHE   A C   1 
ATOM   1698 O O   . PHE   A 1 255 ? -45.830 -24.400 1.662   1.00 42.37  ? 628 PHE   A O   1 
ATOM   1699 C CB  . PHE   A 1 255 ? -43.081 -23.549 2.049   1.00 41.06  ? 628 PHE   A CB  1 
ATOM   1700 C CG  . PHE   A 1 255 ? -42.481 -24.896 1.675   1.00 41.69  ? 628 PHE   A CG  1 
ATOM   1701 C CD1 . PHE   A 1 255 ? -41.500 -24.987 0.696   1.00 41.99  ? 628 PHE   A CD1 1 
ATOM   1702 C CD2 . PHE   A 1 255 ? -42.842 -26.049 2.349   1.00 46.61  ? 628 PHE   A CD2 1 
ATOM   1703 C CE1 . PHE   A 1 255 ? -40.970 -26.212 0.335   1.00 40.88  ? 628 PHE   A CE1 1 
ATOM   1704 C CE2 . PHE   A 1 255 ? -42.270 -27.267 2.017   1.00 46.15  ? 628 PHE   A CE2 1 
ATOM   1705 C CZ  . PHE   A 1 255 ? -41.355 -27.344 0.998   1.00 44.77  ? 628 PHE   A CZ  1 
ATOM   1706 N N   . ILE   A 1 256 ? -45.175 -24.501 -0.494  1.00 36.77  ? 629 ILE   A N   1 
ATOM   1707 C CA  . ILE   A 1 256 ? -46.269 -25.348 -0.919  1.00 37.48  ? 629 ILE   A CA  1 
ATOM   1708 C C   . ILE   A 1 256 ? -45.709 -26.564 -1.652  1.00 39.63  ? 629 ILE   A C   1 
ATOM   1709 O O   . ILE   A 1 256 ? -44.743 -26.474 -2.414  1.00 37.53  ? 629 ILE   A O   1 
ATOM   1710 C CB  . ILE   A 1 256 ? -47.249 -24.579 -1.803  1.00 38.00  ? 629 ILE   A CB  1 
ATOM   1711 C CG1 . ILE   A 1 256 ? -47.635 -23.227 -1.145  1.00 40.86  ? 629 ILE   A CG1 1 
ATOM   1712 C CG2 . ILE   A 1 256 ? -48.469 -25.443 -2.134  1.00 38.45  ? 629 ILE   A CG2 1 
ATOM   1713 C CD1 . ILE   A 1 256 ? -48.860 -22.551 -1.745  1.00 41.06  ? 629 ILE   A CD1 1 
ATOM   1714 N N   . GLN   A 1 257 ? -46.351 -27.700 -1.412  1.00 41.27  ? 630 GLN   A N   1 
ATOM   1715 C CA  . GLN   A 1 257 ? -46.037 -28.916 -2.114  1.00 41.97  ? 630 GLN   A CA  1 
ATOM   1716 C C   . GLN   A 1 257 ? -47.197 -29.271 -3.030  1.00 40.84  ? 630 GLN   A C   1 
ATOM   1717 O O   . GLN   A 1 257 ? -48.349 -29.299 -2.593  1.00 41.84  ? 630 GLN   A O   1 
ATOM   1718 C CB  . GLN   A 1 257 ? -45.763 -29.996 -1.073  1.00 45.35  ? 630 GLN   A CB  1 
ATOM   1719 C CG  . GLN   A 1 257 ? -45.211 -31.288 -1.673  1.00 49.19  ? 630 GLN   A CG  1 
ATOM   1720 C CD  . GLN   A 1 257 ? -45.125 -32.402 -0.659  1.00 55.03  ? 630 GLN   A CD  1 
ATOM   1721 O OE1 . GLN   A 1 257 ? -45.585 -32.249 0.489   1.00 60.65  ? 630 GLN   A OE1 1 
ATOM   1722 N NE2 . GLN   A 1 257 ? -44.550 -33.531 -1.079  1.00 50.79  ? 630 GLN   A NE2 1 
ATOM   1723 N N   . TRP   A 1 258 ? -46.876 -29.580 -4.288  1.00 40.32  ? 631 TRP   A N   1 
ATOM   1724 C CA  . TRP   A 1 258 ? -47.884 -29.768 -5.319  1.00 41.43  ? 631 TRP   A CA  1 
ATOM   1725 C C   . TRP   A 1 258 ? -47.775 -31.157 -5.921  1.00 44.44  ? 631 TRP   A C   1 
ATOM   1726 O O   . TRP   A 1 258 ? -46.680 -31.568 -6.265  1.00 42.17  ? 631 TRP   A O   1 
ATOM   1727 C CB  . TRP   A 1 258 ? -47.682 -28.748 -6.435  1.00 39.07  ? 631 TRP   A CB  1 
ATOM   1728 C CG  . TRP   A 1 258 ? -47.589 -27.334 -5.969  1.00 37.26  ? 631 TRP   A CG  1 
ATOM   1729 C CD1 . TRP   A 1 258 ? -46.474 -26.594 -5.675  1.00 33.61  ? 631 TRP   A CD1 1 
ATOM   1730 C CD2 . TRP   A 1 258 ? -48.713 -26.474 -5.809  1.00 36.74  ? 631 TRP   A CD2 1 
ATOM   1731 N NE1 . TRP   A 1 258 ? -46.844 -25.329 -5.305  1.00 34.29  ? 631 TRP   A NE1 1 
ATOM   1732 C CE2 . TRP   A 1 258 ? -48.210 -25.222 -5.409  1.00 35.86  ? 631 TRP   A CE2 1 
ATOM   1733 C CE3 . TRP   A 1 258 ? -50.082 -26.639 -6.001  1.00 39.33  ? 631 TRP   A CE3 1 
ATOM   1734 C CZ2 . TRP   A 1 258 ? -49.053 -24.147 -5.173  1.00 37.61  ? 631 TRP   A CZ2 1 
ATOM   1735 C CZ3 . TRP   A 1 258 ? -50.920 -25.579 -5.755  1.00 40.28  ? 631 TRP   A CZ3 1 
ATOM   1736 C CH2 . TRP   A 1 258 ? -50.411 -24.349 -5.346  1.00 40.15  ? 631 TRP   A CH2 1 
ATOM   1737 N N   . ASN   A 1 259 ? -48.936 -31.781 -6.191  1.00 49.92  ? 632 ASN   A N   1 
ATOM   1738 C CA  . ASN   A 1 259 ? -48.999 -33.117 -6.763  1.00 51.11  ? 632 ASN   A CA  1 
ATOM   1739 C C   . ASN   A 1 259 ? -48.811 -33.031 -8.281  1.00 50.68  ? 632 ASN   A C   1 
ATOM   1740 O O   . ASN   A 1 259 ? -49.703 -32.570 -8.994  1.00 52.99  ? 632 ASN   A O   1 
ATOM   1741 C CB  . ASN   A 1 259 ? -50.310 -33.797 -6.396  1.00 51.00  ? 632 ASN   A CB  1 
ATOM   1742 C CG  . ASN   A 1 259 ? -50.396 -35.232 -6.872  1.00 53.61  ? 632 ASN   A CG  1 
ATOM   1743 O OD1 . ASN   A 1 259 ? -49.660 -35.655 -7.771  1.00 53.20  ? 632 ASN   A OD1 1 
ATOM   1744 N ND2 . ASN   A 1 259 ? -51.305 -36.001 -6.295  1.00 55.92  ? 632 ASN   A ND2 1 
ATOM   1745 N N   . ILE   A 1 260 ? -47.684 -33.575 -8.759  1.00 47.89  ? 633 ILE   A N   1 
ATOM   1746 C CA  . ILE   A 1 260 ? -47.274 -33.485 -10.160 1.00 52.13  ? 633 ILE   A CA  1 
ATOM   1747 C C   . ILE   A 1 260 ? -48.204 -34.306 -11.075 1.00 56.18  ? 633 ILE   A C   1 
ATOM   1748 O O   . ILE   A 1 260 ? -48.073 -34.212 -12.286 1.00 60.90  ? 633 ILE   A O   1 
ATOM   1749 C CB  . ILE   A 1 260 ? -45.807 -33.948 -10.303 1.00 53.17  ? 633 ILE   A CB  1 
ATOM   1750 C CG1 . ILE   A 1 260 ? -45.126 -33.232 -11.382 1.00 54.15  ? 633 ILE   A CG1 1 
ATOM   1751 C CG2 . ILE   A 1 260 ? -45.698 -35.479 -10.492 1.00 60.53  ? 633 ILE   A CG2 1 
ATOM   1752 C CD1 . ILE   A 1 260 ? -45.205 -31.725 -11.222 1.00 63.35  ? 633 ILE   A CD1 1 
ATOM   1753 N N   . HIS   A 1 261 ? -49.064 -35.170 -10.497 1.00 55.67  ? 634 HIS   A N   1 
ATOM   1754 C CA  . HIS   A 1 261 ? -49.980 -36.016 -11.265 1.00 63.65  ? 634 HIS   A CA  1 
ATOM   1755 C C   . HIS   A 1 261 ? -51.395 -35.412 -11.335 1.00 61.45  ? 634 HIS   A C   1 
ATOM   1756 O O   . HIS   A 1 261 ? -52.278 -36.082 -11.849 1.00 63.76  ? 634 HIS   A O   1 
ATOM   1757 C CB  . HIS   A 1 261 ? -50.109 -37.475 -10.713 1.00 61.17  ? 634 HIS   A CB  1 
ATOM   1758 C CG  . HIS   A 1 261 ? -48.803 -38.281 -10.511 1.00 63.77  ? 634 HIS   A CG  1 
ATOM   1759 N ND1 . HIS   A 1 261 ? -47.962 -38.714 -11.536 1.00 65.46  ? 634 HIS   A ND1 1 
ATOM   1760 C CD2 . HIS   A 1 261 ? -48.170 -38.698 -9.368  1.00 70.56  ? 634 HIS   A CD2 1 
ATOM   1761 C CE1 . HIS   A 1 261 ? -46.876 -39.361 -11.031 1.00 70.86  ? 634 HIS   A CE1 1 
ATOM   1762 N NE2 . HIS   A 1 261 ? -46.971 -39.343 -9.714  1.00 73.00  ? 634 HIS   A NE2 1 
ATOM   1763 N N   . LYS   A 1 262 ? -51.586 -34.151 -10.890 1.00 57.11  ? 635 LYS   A N   1 
ATOM   1764 C CA  . LYS   A 1 262 ? -52.908 -33.537 -10.772 1.00 59.44  ? 635 LYS   A CA  1 
ATOM   1765 C C   . LYS   A 1 262 ? -52.775 -32.026 -10.579 1.00 65.22  ? 635 LYS   A C   1 
ATOM   1766 O O   . LYS   A 1 262 ? -52.581 -31.562 -9.452  1.00 73.09  ? 635 LYS   A O   1 
ATOM   1767 C CB  . LYS   A 1 262 ? -53.643 -34.134 -9.571  1.00 60.43  ? 635 LYS   A CB  1 
ATOM   1768 C CG  . LYS   A 1 262 ? -54.296 -35.483 -9.826  1.00 68.15  ? 635 LYS   A CG  1 
ATOM   1769 C CD  . LYS   A 1 262 ? -54.393 -36.422 -8.630  1.00 68.93  ? 635 LYS   A CD  1 
ATOM   1770 C CE  . LYS   A 1 262 ? -55.080 -37.698 -8.994  1.00 71.49  ? 635 LYS   A CE  1 
ATOM   1771 N NZ  . LYS   A 1 262 ? -54.202 -38.610 -9.725  1.00 70.69  ? 635 LYS   A NZ  1 
ATOM   1772 N N   . SER   A 1 263 ? -52.910 -31.268 -11.683 1.00 68.26  ? 636 SER   A N   1 
ATOM   1773 C CA  . SER   A 1 263 ? -52.531 -29.848 -11.776 1.00 61.81  ? 636 SER   A CA  1 
ATOM   1774 C C   . SER   A 1 263 ? -53.211 -28.952 -10.710 1.00 62.89  ? 636 SER   A C   1 
ATOM   1775 O O   . SER   A 1 263 ? -54.433 -28.785 -10.694 1.00 59.08  ? 636 SER   A O   1 
ATOM   1776 C CB  . SER   A 1 263 ? -52.848 -29.362 -13.199 1.00 65.09  ? 636 SER   A CB  1 
ATOM   1777 O OG  . SER   A 1 263 ? -53.030 -27.953 -13.293 1.00 66.90  ? 636 SER   A OG  1 
ATOM   1778 N N   . GLY   A 1 264 ? -52.397 -28.332 -9.828  1.00 66.48  ? 637 GLY   A N   1 
ATOM   1779 C CA  . GLY   A 1 264 ? -52.880 -27.354 -8.852  1.00 58.89  ? 637 GLY   A CA  1 
ATOM   1780 C C   . GLY   A 1 264 ? -53.491 -28.016 -7.614  1.00 67.56  ? 637 GLY   A C   1 
ATOM   1781 O O   . GLY   A 1 264 ? -54.077 -27.330 -6.766  1.00 61.73  ? 637 GLY   A O   1 
ATOM   1782 N N   . LEU   A 1 265 ? -53.369 -29.356 -7.506  1.00 68.90  ? 638 LEU   A N   1 
ATOM   1783 C CA  . LEU   A 1 265 ? -53.765 -30.040 -6.281  1.00 61.35  ? 638 LEU   A CA  1 
ATOM   1784 C C   . LEU   A 1 265 ? -52.611 -29.927 -5.292  1.00 56.35  ? 638 LEU   A C   1 
ATOM   1785 O O   . LEU   A 1 265 ? -51.531 -30.508 -5.501  1.00 52.69  ? 638 LEU   A O   1 
ATOM   1786 C CB  . LEU   A 1 265 ? -54.184 -31.499 -6.485  1.00 61.74  ? 638 LEU   A CB  1 
ATOM   1787 C CG  . LEU   A 1 265 ? -54.467 -32.280 -5.188  1.00 65.52  ? 638 LEU   A CG  1 
ATOM   1788 C CD1 . LEU   A 1 265 ? -55.477 -31.568 -4.291  1.00 67.82  ? 638 LEU   A CD1 1 
ATOM   1789 C CD2 . LEU   A 1 265 ? -54.924 -33.680 -5.459  1.00 65.51  ? 638 LEU   A CD2 1 
ATOM   1790 N N   . LYS   A 1 266 ? -52.843 -29.134 -4.242  1.00 55.74  ? 639 LYS   A N   1 
ATOM   1791 C CA  . LYS   A 1 266 ? -51.878 -28.974 -3.180  1.00 55.86  ? 639 LYS   A CA  1 
ATOM   1792 C C   . LYS   A 1 266 ? -51.798 -30.288 -2.417  1.00 54.21  ? 639 LYS   A C   1 
ATOM   1793 O O   . LYS   A 1 266 ? -52.768 -31.024 -2.329  1.00 54.19  ? 639 LYS   A O   1 
ATOM   1794 C CB  . LYS   A 1 266 ? -52.225 -27.890 -2.146  1.00 59.42  ? 639 LYS   A CB  1 
ATOM   1795 C CG  . LYS   A 1 266 ? -52.401 -26.468 -2.637  1.00 61.65  ? 639 LYS   A CG  1 
ATOM   1796 C CD  . LYS   A 1 266 ? -52.465 -25.475 -1.486  1.00 63.35  ? 639 LYS   A CD  1 
ATOM   1797 C CE  . LYS   A 1 266 ? -53.633 -24.535 -1.546  1.00 71.20  ? 639 LYS   A CE  1 
ATOM   1798 N NZ  . LYS   A 1 266 ? -53.316 -23.317 -2.281  1.00 71.38  ? 639 LYS   A NZ  1 
ATOM   1799 N N   . VAL   A 1 267 ? -50.620 -30.557 -1.873  1.00 52.96  ? 640 VAL   A N   1 
ATOM   1800 C CA  . VAL   A 1 267 ? -50.424 -31.677 -0.989  1.00 52.49  ? 640 VAL   A CA  1 
ATOM   1801 C C   . VAL   A 1 267 ? -50.298 -31.136 0.421   1.00 52.91  ? 640 VAL   A C   1 
ATOM   1802 O O   . VAL   A 1 267 ? -50.842 -31.709 1.366   1.00 52.96  ? 640 VAL   A O   1 
ATOM   1803 C CB  . VAL   A 1 267 ? -49.185 -32.489 -1.407  1.00 50.86  ? 640 VAL   A CB  1 
ATOM   1804 C CG1 . VAL   A 1 267 ? -48.932 -33.667 -0.454  1.00 56.50  ? 640 VAL   A CG1 1 
ATOM   1805 C CG2 . VAL   A 1 267 ? -49.319 -32.973 -2.846  1.00 49.56  ? 640 VAL   A CG2 1 
ATOM   1806 N N   . SER   A 1 268 ? -49.566 -30.026 0.544   1.00 50.20  ? 641 SER   A N   1 
ATOM   1807 C CA  . SER   A 1 268 ? -49.458 -29.332 1.812   1.00 48.77  ? 641 SER   A CA  1 
ATOM   1808 C C   . SER   A 1 268 ? -49.026 -27.898 1.551   1.00 47.67  ? 641 SER   A C   1 
ATOM   1809 O O   . SER   A 1 268 ? -48.540 -27.571 0.456   1.00 43.43  ? 641 SER   A O   1 
ATOM   1810 C CB  . SER   A 1 268 ? -48.492 -30.027 2.728   1.00 50.13  ? 641 SER   A CB  1 
ATOM   1811 O OG  . SER   A 1 268 ? -47.171 -29.975 2.194   1.00 50.18  ? 641 SER   A OG  1 
ATOM   1812 N N   . GLU   A 1 269 ? -49.104 -27.086 2.606   1.00 49.75  ? 642 GLU   A N   1 
ATOM   1813 C CA  . GLU   A 1 269 ? -48.973 -25.653 2.497   1.00 52.46  ? 642 GLU   A CA  1 
ATOM   1814 C C   . GLU   A 1 269 ? -48.602 -25.125 3.871   1.00 52.59  ? 642 GLU   A C   1 
ATOM   1815 O O   . GLU   A 1 269 ? -49.254 -25.443 4.828   1.00 50.32  ? 642 GLU   A O   1 
ATOM   1816 C CB  . GLU   A 1 269 ? -50.312 -25.163 1.943   1.00 59.95  ? 642 GLU   A CB  1 
ATOM   1817 C CG  . GLU   A 1 269 ? -50.580 -23.674 2.143   1.00 68.10  ? 642 GLU   A CG  1 
ATOM   1818 C CD  . GLU   A 1 269 ? -51.793 -23.185 1.380   1.00 73.00  ? 642 GLU   A CD  1 
ATOM   1819 O OE1 . GLU   A 1 269 ? -52.886 -23.777 1.553   1.00 79.74  ? 642 GLU   A OE1 1 
ATOM   1820 O OE2 . GLU   A 1 269 ? -51.630 -22.228 0.590   1.00 80.00  ? 642 GLU   A OE2 1 
ATOM   1821 N N   . TYR   A 1 270 ? -47.509 -24.379 3.956   1.00 54.41  ? 643 TYR   A N   1 
ATOM   1822 C CA  . TYR   A 1 270 ? -47.082 -23.776 5.205   1.00 55.01  ? 643 TYR   A CA  1 
ATOM   1823 C C   . TYR   A 1 270 ? -46.781 -22.300 4.957   1.00 51.14  ? 643 TYR   A C   1 
ATOM   1824 O O   . TYR   A 1 270 ? -46.166 -21.937 3.954   1.00 48.37  ? 643 TYR   A O   1 
ATOM   1825 C CB  . TYR   A 1 270 ? -45.873 -24.565 5.724   1.00 57.40  ? 643 TYR   A CB  1 
ATOM   1826 C CG  . TYR   A 1 270 ? -46.173 -26.045 5.950   1.00 67.16  ? 643 TYR   A CG  1 
ATOM   1827 C CD1 . TYR   A 1 270 ? -46.751 -26.479 7.143   1.00 70.05  ? 643 TYR   A CD1 1 
ATOM   1828 C CD2 . TYR   A 1 270 ? -45.920 -27.014 4.964   1.00 68.54  ? 643 TYR   A CD2 1 
ATOM   1829 C CE1 . TYR   A 1 270 ? -47.047 -27.818 7.362   1.00 72.31  ? 643 TYR   A CE1 1 
ATOM   1830 C CE2 . TYR   A 1 270 ? -46.223 -28.359 5.173   1.00 68.58  ? 643 TYR   A CE2 1 
ATOM   1831 C CZ  . TYR   A 1 270 ? -46.781 -28.760 6.382   1.00 76.54  ? 643 TYR   A CZ  1 
ATOM   1832 O OH  . TYR   A 1 270 ? -47.109 -30.065 6.639   1.00 87.34  ? 643 TYR   A OH  1 
ATOM   1833 N N   . SER   A 1 271 ? -47.250 -21.455 5.862   1.00 53.57  ? 644 SER   A N   1 
ATOM   1834 C CA  . SER   A 1 271 ? -46.790 -20.079 5.971   1.00 52.76  ? 644 SER   A CA  1 
ATOM   1835 C C   . SER   A 1 271 ? -45.436 -20.052 6.671   1.00 50.29  ? 644 SER   A C   1 
ATOM   1836 O O   . SER   A 1 271 ? -45.349 -20.288 7.871   1.00 53.29  ? 644 SER   A O   1 
ATOM   1837 C CB  . SER   A 1 271 ? -47.801 -19.246 6.721   1.00 55.23  ? 644 SER   A CB  1 
ATOM   1838 O OG  . SER   A 1 271 ? -48.988 -19.154 5.951   1.00 57.55  ? 644 SER   A OG  1 
ATOM   1839 N N   . LEU   A 1 272 ? -44.380 -19.765 5.921   1.00 47.59  ? 645 LEU   A N   1 
ATOM   1840 C CA  . LEU   A 1 272 ? -43.074 -19.593 6.530   1.00 49.80  ? 645 LEU   A CA  1 
ATOM   1841 C C   . LEU   A 1 272 ? -43.009 -18.235 7.230   1.00 49.90  ? 645 LEU   A C   1 
ATOM   1842 O O   . LEU   A 1 272 ? -43.822 -17.341 6.960   1.00 48.88  ? 645 LEU   A O   1 
ATOM   1843 C CB  . LEU   A 1 272 ? -41.999 -19.735 5.457   1.00 51.35  ? 645 LEU   A CB  1 
ATOM   1844 C CG  . LEU   A 1 272 ? -41.780 -21.155 4.914   1.00 53.97  ? 645 LEU   A CG  1 
ATOM   1845 C CD1 . LEU   A 1 272 ? -40.539 -21.196 4.076   1.00 55.08  ? 645 LEU   A CD1 1 
ATOM   1846 C CD2 . LEU   A 1 272 ? -41.676 -22.176 6.014   1.00 56.67  ? 645 LEU   A CD2 1 
ATOM   1847 N N   . PRO   A 1 273 ? -42.068 -18.035 8.180   1.00 50.72  ? 646 PRO   A N   1 
ATOM   1848 C CA  . PRO   A 1 273 ? -41.812 -16.691 8.701   1.00 52.67  ? 646 PRO   A CA  1 
ATOM   1849 C C   . PRO   A 1 273 ? -41.441 -15.758 7.548   1.00 49.43  ? 646 PRO   A C   1 
ATOM   1850 O O   . PRO   A 1 273 ? -40.851 -16.177 6.563   1.00 48.37  ? 646 PRO   A O   1 
ATOM   1851 C CB  . PRO   A 1 273 ? -40.671 -16.872 9.741   1.00 53.03  ? 646 PRO   A CB  1 
ATOM   1852 C CG  . PRO   A 1 273 ? -40.726 -18.370 10.086  1.00 53.88  ? 646 PRO   A CG  1 
ATOM   1853 C CD  . PRO   A 1 273 ? -41.243 -19.072 8.827   1.00 50.44  ? 646 PRO   A CD  1 
ATOM   1854 N N   . SER   A 1 274 ? -41.856 -14.503 7.680   1.00 50.98  ? 647 SER   A N   1 
ATOM   1855 C CA  . SER   A 1 274 ? -41.628 -13.441 6.718   1.00 50.56  ? 647 SER   A CA  1 
ATOM   1856 C C   . SER   A 1 274 ? -40.205 -13.421 6.182   1.00 45.68  ? 647 SER   A C   1 
ATOM   1857 O O   . SER   A 1 274 ? -40.021 -13.084 5.027   1.00 43.92  ? 647 SER   A O   1 
ATOM   1858 C CB  . SER   A 1 274 ? -41.953 -12.113 7.332   1.00 54.25  ? 647 SER   A CB  1 
ATOM   1859 O OG  . SER   A 1 274 ? -43.286 -11.784 6.989   1.00 63.27  ? 647 SER   A OG  1 
ATOM   1860 N N   . ASP   A 1 275 ? -39.229 -13.670 7.070   1.00 44.92  ? 648 ASP   A N   1 
ATOM   1861 C CA  . ASP   A 1 275 ? -37.817 -13.450 6.818   1.00 44.91  ? 648 ASP   A CA  1 
ATOM   1862 C C   . ASP   A 1 275 ? -37.235 -14.627 6.035   1.00 45.77  ? 648 ASP   A C   1 
ATOM   1863 O O   . ASP   A 1 275 ? -36.036 -14.647 5.731   1.00 46.20  ? 648 ASP   A O   1 
ATOM   1864 C CB  . ASP   A 1 275 ? -37.058 -13.175 8.113   1.00 47.62  ? 648 ASP   A CB  1 
ATOM   1865 C CG  . ASP   A 1 275 ? -36.949 -14.330 9.101   1.00 50.01  ? 648 ASP   A CG  1 
ATOM   1866 O OD1 . ASP   A 1 275 ? -37.563 -15.380 8.878   1.00 50.93  ? 648 ASP   A OD1 1 
ATOM   1867 O OD2 . ASP   A 1 275 ? -36.222 -14.184 10.068  1.00 56.40  ? 648 ASP   A OD2 1 
ATOM   1868 N N   . ALA   A 1 276 ? -38.094 -15.601 5.719   1.00 43.95  ? 649 ALA   A N   1 
ATOM   1869 C CA  . ALA   A 1 276 ? -37.758 -16.631 4.758   1.00 42.97  ? 649 ALA   A CA  1 
ATOM   1870 C C   . ALA   A 1 276 ? -37.902 -16.106 3.330   1.00 41.90  ? 649 ALA   A C   1 
ATOM   1871 O O   . ALA   A 1 276 ? -37.260 -16.639 2.446   1.00 36.94  ? 649 ALA   A O   1 
ATOM   1872 C CB  . ALA   A 1 276 ? -38.637 -17.837 4.970   1.00 42.66  ? 649 ALA   A CB  1 
ATOM   1873 N N   . THR   A 1 277 ? -38.818 -15.139 3.095   1.00 42.34  ? 650 THR   A N   1 
ATOM   1874 C CA  . THR   A 1 277 ? -39.120 -14.703 1.741   1.00 40.37  ? 650 THR   A CA  1 
ATOM   1875 C C   . THR   A 1 277 ? -38.908 -13.195 1.576   1.00 43.22  ? 650 THR   A C   1 
ATOM   1876 O O   . THR   A 1 277 ? -38.995 -12.676 0.465   1.00 40.92  ? 650 THR   A O   1 
ATOM   1877 C CB  . THR   A 1 277 ? -40.544 -15.091 1.356   1.00 41.79  ? 650 THR   A CB  1 
ATOM   1878 O OG1 . THR   A 1 277 ? -41.292 -14.550 2.428   1.00 43.17  ? 650 THR   A OG1 1 
ATOM   1879 C CG2 . THR   A 1 277 ? -40.736 -16.588 1.156   1.00 40.99  ? 650 THR   A CG2 1 
ATOM   1880 N N   . GLY   A 1 278 ? -38.578 -12.501 2.664   1.00 47.82  ? 651 GLY   A N   1 
ATOM   1881 C CA  . GLY   A 1 278 ? -38.292 -11.080 2.573   1.00 50.68  ? 651 GLY   A CA  1 
ATOM   1882 C C   . GLY   A 1 278 ? -39.553 -10.292 2.227   1.00 54.78  ? 651 GLY   A C   1 
ATOM   1883 O O   . GLY   A 1 278 ? -40.667 -10.723 2.543   1.00 57.25  ? 651 GLY   A O   1 
ATOM   1884 N N   . PRO   A 1 279 ? -39.442 -9.098  1.606   1.00 58.34  ? 652 PRO   A N   1 
ATOM   1885 C CA  . PRO   A 1 279 ? -38.160 -8.538  1.140   1.00 54.01  ? 652 PRO   A CA  1 
ATOM   1886 C C   . PRO   A 1 279 ? -37.082 -8.390  2.213   1.00 50.27  ? 652 PRO   A C   1 
ATOM   1887 O O   . PRO   A 1 279 ? -37.380 -8.156  3.381   1.00 52.28  ? 652 PRO   A O   1 
ATOM   1888 C CB  . PRO   A 1 279 ? -38.584 -7.144  0.598   1.00 61.72  ? 652 PRO   A CB  1 
ATOM   1889 C CG  . PRO   A 1 279 ? -40.074 -7.267  0.317   1.00 64.68  ? 652 PRO   A CG  1 
ATOM   1890 C CD  . PRO   A 1 279 ? -40.575 -8.171  1.420   1.00 65.36  ? 652 PRO   A CD  1 
ATOM   1891 N N   . PHE   A 1 280 ? -35.815 -8.492  1.811   1.00 46.21  ? 653 PHE   A N   1 
ATOM   1892 C CA  . PHE   A 1 280 ? -34.733 -8.498  2.781   1.00 47.34  ? 653 PHE   A CA  1 
ATOM   1893 C C   . PHE   A 1 280 ? -34.225 -7.062  3.001   1.00 50.29  ? 653 PHE   A C   1 
ATOM   1894 O O   . PHE   A 1 280 ? -33.877 -6.358  2.060   1.00 50.11  ? 653 PHE   A O   1 
ATOM   1895 C CB  . PHE   A 1 280 ? -33.677 -9.489  2.281   1.00 48.12  ? 653 PHE   A CB  1 
ATOM   1896 C CG  . PHE   A 1 280 ? -34.200 -10.905 2.014   1.00 45.85  ? 653 PHE   A CG  1 
ATOM   1897 C CD1 . PHE   A 1 280 ? -34.648 -11.718 3.065   1.00 43.60  ? 653 PHE   A CD1 1 
ATOM   1898 C CD2 . PHE   A 1 280 ? -34.190 -11.439 0.728   1.00 43.68  ? 653 PHE   A CD2 1 
ATOM   1899 C CE1 . PHE   A 1 280 ? -35.125 -13.008 2.824   1.00 45.85  ? 653 PHE   A CE1 1 
ATOM   1900 C CE2 . PHE   A 1 280 ? -34.631 -12.748 0.496   1.00 45.00  ? 653 PHE   A CE2 1 
ATOM   1901 C CZ  . PHE   A 1 280 ? -35.124 -13.520 1.538   1.00 42.52  ? 653 PHE   A CZ  1 
ATOM   1902 N N   . VAL   A 1 281 ? -34.159 -6.642  4.268   1.00 50.26  ? 654 VAL   A N   1 
ATOM   1903 C CA  . VAL   A 1 281 ? -33.946 -5.251  4.609   1.00 52.21  ? 654 VAL   A CA  1 
ATOM   1904 C C   . VAL   A 1 281 ? -32.811 -5.150  5.623   1.00 54.36  ? 654 VAL   A C   1 
ATOM   1905 O O   . VAL   A 1 281 ? -32.855 -5.777  6.673   1.00 56.49  ? 654 VAL   A O   1 
ATOM   1906 C CB  . VAL   A 1 281 ? -35.208 -4.559  5.158   1.00 52.62  ? 654 VAL   A CB  1 
ATOM   1907 C CG1 . VAL   A 1 281 ? -34.904 -3.133  5.555   1.00 56.69  ? 654 VAL   A CG1 1 
ATOM   1908 C CG2 . VAL   A 1 281 ? -36.379 -4.600  4.178   1.00 51.07  ? 654 VAL   A CG2 1 
ATOM   1909 N N   . LEU   A 1 282 ? -31.812 -4.328  5.295   1.00 56.45  ? 655 LEU   A N   1 
ATOM   1910 C CA  . LEU   A 1 282 ? -30.771 -3.942  6.229   1.00 59.67  ? 655 LEU   A CA  1 
ATOM   1911 C C   . LEU   A 1 282 ? -30.854 -2.429  6.509   1.00 62.57  ? 655 LEU   A C   1 
ATOM   1912 O O   . LEU   A 1 282 ? -30.756 -1.621  5.589   1.00 60.97  ? 655 LEU   A O   1 
ATOM   1913 C CB  . LEU   A 1 282 ? -29.459 -4.353  5.568   1.00 59.06  ? 655 LEU   A CB  1 
ATOM   1914 C CG  . LEU   A 1 282 ? -28.235 -4.415  6.475   1.00 62.38  ? 655 LEU   A CG  1 
ATOM   1915 C CD1 . LEU   A 1 282 ? -28.464 -5.243  7.734   1.00 63.63  ? 655 LEU   A CD1 1 
ATOM   1916 C CD2 . LEU   A 1 282 ? -27.084 -4.955  5.667   1.00 59.86  ? 655 LEU   A CD2 1 
ATOM   1917 N N   . SER   A 1 283 ? -31.087 -2.057  7.781   1.00 66.84  ? 656 SER   A N   1 
ATOM   1918 C CA  . SER   A 1 283 ? -31.214 -0.659  8.187   1.00 72.25  ? 656 SER   A CA  1 
ATOM   1919 C C   . SER   A 1 283 ? -30.068 -0.252  9.102   1.00 75.13  ? 656 SER   A C   1 
ATOM   1920 O O   . SER   A 1 283 ? -29.482 -1.077  9.782   1.00 72.53  ? 656 SER   A O   1 
ATOM   1921 C CB  . SER   A 1 283 ? -32.523 -0.383  8.886   1.00 74.18  ? 656 SER   A CB  1 
ATOM   1922 O OG  . SER   A 1 283 ? -33.617 -0.952  8.179   1.00 77.38  ? 656 SER   A OG  1 
ATOM   1923 N N   . GLY   A 1 284 ? -29.774 1.052   9.097   1.00 86.65  ? 657 GLY   A N   1 
ATOM   1924 C CA  . GLY   A 1 284 ? -29.157 1.736   10.223  1.00 90.05  ? 657 GLY   A CA  1 
ATOM   1925 C C   . GLY   A 1 284 ? -30.096 2.830   10.720  1.00 96.01  ? 657 GLY   A C   1 
ATOM   1926 O O   . GLY   A 1 284 ? -31.226 2.928   10.243  1.00 95.86  ? 657 GLY   A O   1 
ATOM   1927 N N   . TYR   A 1 285 ? -29.611 3.681   11.636  1.00 102.26 ? 658 TYR   A N   1 
ATOM   1928 C CA  . TYR   A 1 285 ? -30.478 4.635   12.310  1.00 101.85 ? 658 TYR   A CA  1 
ATOM   1929 C C   . TYR   A 1 285 ? -30.868 5.769   11.354  1.00 102.39 ? 658 TYR   A C   1 
ATOM   1930 O O   . TYR   A 1 285 ? -31.696 6.610   11.709  1.00 123.48 ? 658 TYR   A O   1 
ATOM   1931 C CB  . TYR   A 1 285 ? -29.789 5.160   13.574  1.00 106.30 ? 658 TYR   A CB  1 
ATOM   1932 N N   . SER   A 1 286 ? -30.362 5.725   10.110  1.00 91.69  ? 659 SER   A N   1 
ATOM   1933 C CA  . SER   A 1 286 ? -30.035 6.920   9.334   1.00 95.10  ? 659 SER   A CA  1 
ATOM   1934 C C   . SER   A 1 286 ? -31.195 7.374   8.438   1.00 95.35  ? 659 SER   A C   1 
ATOM   1935 O O   . SER   A 1 286 ? -31.180 8.485   7.889   1.00 112.50 ? 659 SER   A O   1 
ATOM   1936 C CB  . SER   A 1 286 ? -28.788 6.662   8.509   1.00 88.69  ? 659 SER   A CB  1 
ATOM   1937 N N   . GLY   A 1 287 ? -32.221 6.525   8.316   1.00 90.87  ? 660 GLY   A N   1 
ATOM   1938 C CA  . GLY   A 1 287 ? -33.196 6.695   7.247   1.00 90.99  ? 660 GLY   A CA  1 
ATOM   1939 C C   . GLY   A 1 287 ? -32.806 5.814   5.966   1.00 85.45  ? 660 GLY   A C   1 
ATOM   1940 O O   . GLY   A 1 287 ? -33.546 5.718   4.934   1.00 84.91  ? 660 GLY   A O   1 
ATOM   1941 N N   . TYR   A 1 288 ? -31.616 5.184   6.082   1.00 74.65  ? 661 TYR   A N   1 
ATOM   1942 C CA  . TYR   A 1 288 ? -30.936 4.580   4.939   1.00 74.40  ? 661 TYR   A CA  1 
ATOM   1943 C C   . TYR   A 1 288 ? -31.108 3.040   5.019   1.00 74.15  ? 661 TYR   A C   1 
ATOM   1944 O O   . TYR   A 1 288 ? -30.609 2.362   5.923   1.00 78.92  ? 661 TYR   A O   1 
ATOM   1945 C CB  . TYR   A 1 288 ? -29.444 4.963   4.875   1.00 73.03  ? 661 TYR   A CB  1 
ATOM   1946 C CG  . TYR   A 1 288 ? -28.758 4.443   3.614   1.00 74.81  ? 661 TYR   A CG  1 
ATOM   1947 C CD1 . TYR   A 1 288 ? -28.219 3.144   3.565   1.00 72.15  ? 661 TYR   A CD1 1 
ATOM   1948 C CD2 . TYR   A 1 288 ? -28.739 5.200   2.442   1.00 76.75  ? 661 TYR   A CD2 1 
ATOM   1949 C CE1 . TYR   A 1 288 ? -27.638 2.649   2.406   1.00 70.31  ? 661 TYR   A CE1 1 
ATOM   1950 C CE2 . TYR   A 1 288 ? -28.154 4.715   1.281   1.00 76.55  ? 661 TYR   A CE2 1 
ATOM   1951 C CZ  . TYR   A 1 288 ? -27.600 3.440   1.266   1.00 74.18  ? 661 TYR   A CZ  1 
ATOM   1952 O OH  . TYR   A 1 288 ? -27.023 3.007   0.113   1.00 77.48  ? 661 TYR   A OH  1 
ATOM   1953 N N   . LYS   A 1 289 ? -31.792 2.461   4.033   1.00 66.95  ? 662 LYS   A N   1 
ATOM   1954 C CA  . LYS   A 1 289 ? -31.887 1.004   4.065   1.00 72.36  ? 662 LYS   A CA  1 
ATOM   1955 C C   . LYS   A 1 289 ? -31.480 0.374   2.734   1.00 60.94  ? 662 LYS   A C   1 
ATOM   1956 O O   . LYS   A 1 289 ? -31.516 0.975   1.675   1.00 61.07  ? 662 LYS   A O   1 
ATOM   1957 C CB  . LYS   A 1 289 ? -33.273 0.516   4.565   1.00 74.56  ? 662 LYS   A CB  1 
ATOM   1958 C CG  . LYS   A 1 289 ? -34.441 1.010   3.764   1.00 81.39  ? 662 LYS   A CG  1 
ATOM   1959 C CD  . LYS   A 1 289 ? -35.824 0.611   4.283   1.00 88.20  ? 662 LYS   A CD  1 
ATOM   1960 C CE  . LYS   A 1 289 ? -36.933 1.558   3.785   1.00 96.08  ? 662 LYS   A CE  1 
ATOM   1961 N NZ  . LYS   A 1 289 ? -38.068 0.807   3.238   1.00 91.00  ? 662 LYS   A NZ  1 
ATOM   1962 N N   . GLN   A 1 290 ? -31.004 -0.857  2.849   1.00 64.08  ? 663 GLN   A N   1 
ATOM   1963 C CA  . GLN   A 1 290 ? -30.795 -1.710  1.687   1.00 59.00  ? 663 GLN   A CA  1 
ATOM   1964 C C   . GLN   A 1 290 ? -31.943 -2.693  1.644   1.00 55.64  ? 663 GLN   A C   1 
ATOM   1965 O O   . GLN   A 1 290 ? -32.237 -3.319  2.661   1.00 60.29  ? 663 GLN   A O   1 
ATOM   1966 C CB  . GLN   A 1 290 ? -29.397 -2.309  1.809   1.00 58.47  ? 663 GLN   A CB  1 
ATOM   1967 C CG  . GLN   A 1 290 ? -28.311 -1.230  1.770   1.00 64.71  ? 663 GLN   A CG  1 
ATOM   1968 C CD  . GLN   A 1 290 ? -27.050 -1.567  2.536   1.00 69.78  ? 663 GLN   A CD  1 
ATOM   1969 O OE1 . GLN   A 1 290 ? -26.809 -2.711  2.928   1.00 67.10  ? 663 GLN   A OE1 1 
ATOM   1970 N NE2 . GLN   A 1 290 ? -26.232 -0.546  2.771   1.00 80.42  ? 663 GLN   A NE2 1 
ATOM   1971 N N   . VAL   A 1 291 ? -32.565 -2.808  0.455   1.00 55.51  ? 664 VAL   A N   1 
ATOM   1972 C CA  . VAL   A 1 291 ? -33.650 -3.753  0.206   1.00 52.93  ? 664 VAL   A CA  1 
ATOM   1973 C C   . VAL   A 1 291 ? -33.247 -4.701  -0.927  1.00 53.74  ? 664 VAL   A C   1 
ATOM   1974 O O   . VAL   A 1 291 ? -32.882 -4.230  -2.012  1.00 54.42  ? 664 VAL   A O   1 
ATOM   1975 C CB  . VAL   A 1 291 ? -34.946 -2.983  -0.135  1.00 53.70  ? 664 VAL   A CB  1 
ATOM   1976 C CG1 . VAL   A 1 291 ? -36.160 -3.895  -0.254  1.00 51.36  ? 664 VAL   A CG1 1 
ATOM   1977 C CG2 . VAL   A 1 291 ? -35.243 -1.886  0.870   1.00 55.22  ? 664 VAL   A CG2 1 
ATOM   1978 N N   . GLN   A 1 292 ? -33.354 -6.033  -0.664  1.00 51.70  ? 665 GLN   A N   1 
ATOM   1979 C CA  . GLN   A 1 292 ? -33.094 -7.085  -1.637  1.00 48.70  ? 665 GLN   A CA  1 
ATOM   1980 C C   . GLN   A 1 292 ? -34.362 -7.920  -1.780  1.00 47.82  ? 665 GLN   A C   1 
ATOM   1981 O O   . GLN   A 1 292 ? -34.889 -8.432  -0.797  1.00 49.37  ? 665 GLN   A O   1 
ATOM   1982 C CB  . GLN   A 1 292 ? -31.915 -8.003  -1.268  1.00 50.90  ? 665 GLN   A CB  1 
ATOM   1983 C CG  . GLN   A 1 292 ? -31.301 -8.773  -2.449  1.00 50.72  ? 665 GLN   A CG  1 
ATOM   1984 C CD  . GLN   A 1 292 ? -29.941 -9.410  -2.151  1.00 59.51  ? 665 GLN   A CD  1 
ATOM   1985 O OE1 . GLN   A 1 292 ? -29.279 -9.132  -1.146  1.00 56.39  ? 665 GLN   A OE1 1 
ATOM   1986 N NE2 . GLN   A 1 292 ? -29.491 -10.285 -3.040  1.00 70.54  ? 665 GLN   A NE2 1 
ATOM   1987 N N   . VAL   A 1 293 ? -34.898 -7.970  -2.998  1.00 46.80  ? 666 VAL   A N   1 
ATOM   1988 C CA  . VAL   A 1 293 ? -35.998 -8.864  -3.294  1.00 49.42  ? 666 VAL   A CA  1 
ATOM   1989 C C   . VAL   A 1 293 ? -35.387 -10.218 -3.617  1.00 45.20  ? 666 VAL   A C   1 
ATOM   1990 O O   . VAL   A 1 293 ? -34.265 -10.283 -4.098  1.00 47.43  ? 666 VAL   A O   1 
ATOM   1991 C CB  . VAL   A 1 293 ? -36.911 -8.407  -4.448  1.00 50.05  ? 666 VAL   A CB  1 
ATOM   1992 C CG1 . VAL   A 1 293 ? -37.581 -7.084  -4.146  1.00 53.43  ? 666 VAL   A CG1 1 
ATOM   1993 C CG2 . VAL   A 1 293 ? -36.158 -8.357  -5.780  1.00 52.36  ? 666 VAL   A CG2 1 
ATOM   1994 N N   . PRO   A 1 294 ? -36.106 -11.329 -3.354  1.00 44.72  ? 667 PRO   A N   1 
ATOM   1995 C CA  . PRO   A 1 294 ? -35.585 -12.659 -3.646  1.00 42.25  ? 667 PRO   A CA  1 
ATOM   1996 C C   . PRO   A 1 294 ? -35.164 -12.758 -5.105  1.00 42.60  ? 667 PRO   A C   1 
ATOM   1997 O O   . PRO   A 1 294 ? -35.870 -12.307 -5.984  1.00 46.18  ? 667 PRO   A O   1 
ATOM   1998 C CB  . PRO   A 1 294 ? -36.771 -13.547 -3.322  1.00 42.19  ? 667 PRO   A CB  1 
ATOM   1999 C CG  . PRO   A 1 294 ? -37.500 -12.797 -2.258  1.00 42.21  ? 667 PRO   A CG  1 
ATOM   2000 C CD  . PRO   A 1 294 ? -37.446 -11.363 -2.746  1.00 43.21  ? 667 PRO   A CD  1 
ATOM   2001 N N   . ARG   A 1 295 ? -34.013 -13.351 -5.338  1.00 42.50  ? 668 ARG   A N   1 
ATOM   2002 C CA  . ARG   A 1 295 ? -33.442 -13.458 -6.671  1.00 49.46  ? 668 ARG   A CA  1 
ATOM   2003 C C   . ARG   A 1 295 ? -32.784 -14.827 -6.784  1.00 47.67  ? 668 ARG   A C   1 
ATOM   2004 O O   . ARG   A 1 295 ? -32.959 -15.507 -7.767  1.00 48.30  ? 668 ARG   A O   1 
ATOM   2005 C CB  . ARG   A 1 295 ? -32.429 -12.317 -6.894  1.00 56.83  ? 668 ARG   A CB  1 
ATOM   2006 C CG  . ARG   A 1 295 ? -31.854 -12.133 -8.295  1.00 59.06  ? 668 ARG   A CG  1 
ATOM   2007 C CD  . ARG   A 1 295 ? -32.811 -11.475 -9.318  1.00 57.29  ? 668 ARG   A CD  1 
ATOM   2008 N NE  . ARG   A 1 295 ? -33.800 -12.414 -9.845  1.00 57.32  ? 668 ARG   A NE  1 
ATOM   2009 C CZ  . ARG   A 1 295 ? -33.511 -13.601 -10.457 1.00 58.43  ? 668 ARG   A CZ  1 
ATOM   2010 N NH1 . ARG   A 1 295 ? -32.291 -13.795 -10.961 1.00 49.76  ? 668 ARG   A NH1 1 
ATOM   2011 N NH2 . ARG   A 1 295 ? -34.463 -14.560 -10.585 1.00 45.82  ? 668 ARG   A NH2 1 
ATOM   2012 N N   . GLY   A 1 296 ? -32.005 -15.203 -5.760  1.00 47.83  ? 669 GLY   A N   1 
ATOM   2013 C CA  . GLY   A 1 296 ? -31.406 -16.508 -5.710  1.00 44.57  ? 669 GLY   A CA  1 
ATOM   2014 C C   . GLY   A 1 296 ? -32.378 -17.514 -5.109  1.00 44.99  ? 669 GLY   A C   1 
ATOM   2015 O O   . GLY   A 1 296 ? -33.482 -17.146 -4.687  1.00 45.73  ? 669 GLY   A O   1 
ATOM   2016 N N   . ARG   A 1 297 ? -31.927 -18.769 -5.099  1.00 35.81  ? 670 ARG   A N   1 
ATOM   2017 C CA  . ARG   A 1 297 ? -32.601 -19.882 -4.434  1.00 39.46  ? 670 ARG   A CA  1 
ATOM   2018 C C   . ARG   A 1 297 ? -32.882 -19.583 -2.962  1.00 34.98  ? 670 ARG   A C   1 
ATOM   2019 O O   . ARG   A 1 297 ? -31.961 -19.328 -2.184  1.00 30.93  ? 670 ARG   A O   1 
ATOM   2020 C CB  . ARG   A 1 297 ? -31.669 -21.097 -4.442  1.00 43.02  ? 670 ARG   A CB  1 
ATOM   2021 C CG  . ARG   A 1 297 ? -31.832 -21.919 -5.710  1.00 58.40  ? 670 ARG   A CG  1 
ATOM   2022 C CD  . ARG   A 1 297 ? -31.043 -23.220 -5.627  1.00 74.31  ? 670 ARG   A CD  1 
ATOM   2023 N NE  . ARG   A 1 297 ? -31.673 -24.338 -4.915  1.00 78.43  ? 670 ARG   A NE  1 
ATOM   2024 C CZ  . ARG   A 1 297 ? -32.761 -25.023 -5.310  1.00 73.16  ? 670 ARG   A CZ  1 
ATOM   2025 N NH1 . ARG   A 1 297 ? -32.876 -26.292 -4.963  1.00 63.50  ? 670 ARG   A NH1 1 
ATOM   2026 N NH2 . ARG   A 1 297 ? -33.657 -24.498 -6.137  1.00 65.33  ? 670 ARG   A NH2 1 
ATOM   2027 N N   . LEU   A 1 298 ? -34.152 -19.702 -2.596  1.00 31.55  ? 671 LEU   A N   1 
ATOM   2028 C CA  . LEU   A 1 298 ? -34.612 -19.426 -1.253  1.00 35.75  ? 671 LEU   A CA  1 
ATOM   2029 C C   . LEU   A 1 298 ? -34.687 -20.703 -0.399  1.00 38.17  ? 671 LEU   A C   1 
ATOM   2030 O O   . LEU   A 1 298 ? -34.954 -20.624 0.799   1.00 42.94  ? 671 LEU   A O   1 
ATOM   2031 C CB  . LEU   A 1 298 ? -35.973 -18.757 -1.362  1.00 35.41  ? 671 LEU   A CB  1 
ATOM   2032 C CG  . LEU   A 1 298 ? -35.982 -17.315 -1.874  1.00 41.08  ? 671 LEU   A CG  1 
ATOM   2033 C CD1 . LEU   A 1 298 ? -37.380 -16.734 -1.714  1.00 43.64  ? 671 LEU   A CD1 1 
ATOM   2034 C CD2 . LEU   A 1 298 ? -34.978 -16.453 -1.125  1.00 43.64  ? 671 LEU   A CD2 1 
ATOM   2035 N N   . PHE   A 1 299 ? -34.529 -21.883 -1.011  1.00 36.70  ? 672 PHE   A N   1 
ATOM   2036 C CA  . PHE   A 1 299 ? -34.478 -23.117 -0.249  1.00 37.04  ? 672 PHE   A CA  1 
ATOM   2037 C C   . PHE   A 1 299 ? -33.510 -24.078 -0.915  1.00 37.90  ? 672 PHE   A C   1 
ATOM   2038 O O   . PHE   A 1 299 ? -33.079 -23.871 -2.035  1.00 38.71  ? 672 PHE   A O   1 
ATOM   2039 C CB  . PHE   A 1 299 ? -35.875 -23.723 -0.061  1.00 40.98  ? 672 PHE   A CB  1 
ATOM   2040 C CG  . PHE   A 1 299 ? -36.716 -23.999 -1.303  1.00 40.88  ? 672 PHE   A CG  1 
ATOM   2041 C CD1 . PHE   A 1 299 ? -36.152 -24.188 -2.558  1.00 47.29  ? 672 PHE   A CD1 1 
ATOM   2042 C CD2 . PHE   A 1 299 ? -38.086 -24.129 -1.197  1.00 46.45  ? 672 PHE   A CD2 1 
ATOM   2043 C CE1 . PHE   A 1 299 ? -36.944 -24.513 -3.659  1.00 44.81  ? 672 PHE   A CE1 1 
ATOM   2044 C CE2 . PHE   A 1 299 ? -38.872 -24.418 -2.313  1.00 41.78  ? 672 PHE   A CE2 1 
ATOM   2045 C CZ  . PHE   A 1 299 ? -38.304 -24.624 -3.520  1.00 39.86  ? 672 PHE   A CZ  1 
ATOM   2046 N N   . ALA   A 1 300 ? -33.157 -25.123 -0.191  1.00 39.15  ? 673 ALA   A N   1 
ATOM   2047 C CA  . ALA   A 1 300 ? -32.302 -26.164 -0.714  1.00 39.85  ? 673 ALA   A CA  1 
ATOM   2048 C C   . ALA   A 1 300 ? -32.533 -27.393 0.152   1.00 39.56  ? 673 ALA   A C   1 
ATOM   2049 O O   . ALA   A 1 300 ? -33.202 -27.285 1.153   1.00 44.09  ? 673 ALA   A O   1 
ATOM   2050 C CB  . ALA   A 1 300 ? -30.851 -25.704 -0.755  1.00 35.24  ? 673 ALA   A CB  1 
ATOM   2051 N N   . PHE   A 1 301 ? -32.040 -28.554 -0.278  1.00 42.89  ? 674 PHE   A N   1 
ATOM   2052 C CA  . PHE   A 1 301 ? -32.460 -29.830 0.295   1.00 44.75  ? 674 PHE   A CA  1 
ATOM   2053 C C   . PHE   A 1 301 ? -31.259 -30.747 0.507   1.00 44.13  ? 674 PHE   A C   1 
ATOM   2054 O O   . PHE   A 1 301 ? -30.247 -30.624 -0.179  1.00 43.83  ? 674 PHE   A O   1 
ATOM   2055 C CB  . PHE   A 1 301 ? -33.472 -30.504 -0.649  1.00 44.19  ? 674 PHE   A CB  1 
ATOM   2056 C CG  . PHE   A 1 301 ? -34.692 -29.648 -0.931  1.00 46.45  ? 674 PHE   A CG  1 
ATOM   2057 C CD1 . PHE   A 1 301 ? -34.662 -28.667 -1.922  1.00 53.85  ? 674 PHE   A CD1 1 
ATOM   2058 C CD2 . PHE   A 1 301 ? -35.834 -29.767 -0.165  1.00 47.92  ? 674 PHE   A CD2 1 
ATOM   2059 C CE1 . PHE   A 1 301 ? -35.765 -27.852 -2.152  1.00 52.73  ? 674 PHE   A CE1 1 
ATOM   2060 C CE2 . PHE   A 1 301 ? -36.938 -28.969 -0.416  1.00 51.73  ? 674 PHE   A CE2 1 
ATOM   2061 C CZ  . PHE   A 1 301 ? -36.907 -28.020 -1.410  1.00 48.03  ? 674 PHE   A CZ  1 
ATOM   2062 N N   . ASP   A 1 302 ? -31.425 -31.729 1.402   1.00 44.04  ? 675 ASP   A N   1 
ATOM   2063 C CA  . ASP   A 1 302 ? -30.433 -32.775 1.573   1.00 49.61  ? 675 ASP   A CA  1 
ATOM   2064 C C   . ASP   A 1 302 ? -30.620 -33.829 0.477   1.00 54.45  ? 675 ASP   A C   1 
ATOM   2065 O O   . ASP   A 1 302 ? -31.477 -33.682 -0.411  1.00 48.97  ? 675 ASP   A O   1 
ATOM   2066 C CB  . ASP   A 1 302 ? -30.487 -33.377 2.957   1.00 50.18  ? 675 ASP   A CB  1 
ATOM   2067 C CG  . ASP   A 1 302 ? -31.689 -34.265 3.205   1.00 51.64  ? 675 ASP   A CG  1 
ATOM   2068 O OD1 . ASP   A 1 302 ? -32.691 -34.087 2.505   1.00 50.65  ? 675 ASP   A OD1 1 
ATOM   2069 O OD2 . ASP   A 1 302 ? -31.603 -35.128 4.092   1.00 62.64  ? 675 ASP   A OD2 1 
ATOM   2070 N N   . SER   A 1 303 ? -29.749 -34.847 0.499   1.00 57.15  ? 676 SER   A N   1 
ATOM   2071 C CA  . SER   A 1 303 ? -29.476 -35.664 -0.680  1.00 60.93  ? 676 SER   A CA  1 
ATOM   2072 C C   . SER   A 1 303 ? -30.757 -36.334 -1.168  1.00 57.30  ? 676 SER   A C   1 
ATOM   2073 O O   . SER   A 1 303 ? -30.990 -36.412 -2.368  1.00 53.94  ? 676 SER   A O   1 
ATOM   2074 C CB  . SER   A 1 303 ? -28.422 -36.694 -0.363  1.00 66.74  ? 676 SER   A CB  1 
ATOM   2075 O OG  . SER   A 1 303 ? -28.660 -37.224 0.933   1.00 64.64  ? 676 SER   A OG  1 
ATOM   2076 N N   . GLU   A 1 304 ? -31.585 -36.769 -0.206  1.00 61.35  ? 677 GLU   A N   1 
ATOM   2077 C CA  . GLU   A 1 304 ? -32.767 -37.579 -0.477  1.00 70.46  ? 677 GLU   A CA  1 
ATOM   2078 C C   . GLU   A 1 304 ? -34.024 -36.737 -0.266  1.00 64.20  ? 677 GLU   A C   1 
ATOM   2079 O O   . GLU   A 1 304 ? -35.134 -37.258 -0.223  1.00 64.20  ? 677 GLU   A O   1 
ATOM   2080 C CB  . GLU   A 1 304 ? -32.843 -38.758 0.497   1.00 76.30  ? 677 GLU   A CB  1 
ATOM   2081 C CG  . GLU   A 1 304 ? -31.547 -39.563 0.646   1.00 84.48  ? 677 GLU   A CG  1 
ATOM   2082 C CD  . GLU   A 1 304 ? -31.544 -40.930 -0.027  1.00 85.80  ? 677 GLU   A CD  1 
ATOM   2083 O OE1 . GLU   A 1 304 ? -32.556 -41.672 0.089   1.00 78.34  ? 677 GLU   A OE1 1 
ATOM   2084 O OE2 . GLU   A 1 304 ? -30.511 -41.252 -0.653  1.00 86.89  ? 677 GLU   A OE2 1 
ATOM   2085 N N   . GLY   A 1 305 ? -33.822 -35.454 -0.016  1.00 55.63  ? 678 GLY   A N   1 
ATOM   2086 C CA  . GLY   A 1 305 ? -34.923 -34.539 0.183   1.00 54.40  ? 678 GLY   A CA  1 
ATOM   2087 C C   . GLY   A 1 305 ? -35.786 -34.895 1.392   1.00 51.99  ? 678 GLY   A C   1 
ATOM   2088 O O   . GLY   A 1 305 ? -37.003 -34.791 1.333   1.00 52.28  ? 678 GLY   A O   1 
ATOM   2089 N N   . ASN   A 1 306 ? -35.156 -35.150 2.534   1.00 52.32  ? 679 ASN   A N   1 
ATOM   2090 C CA  . ASN   A 1 306 ? -35.923 -35.265 3.762   1.00 53.98  ? 679 ASN   A CA  1 
ATOM   2091 C C   . ASN   A 1 306 ? -35.892 -33.980 4.568   1.00 50.70  ? 679 ASN   A C   1 
ATOM   2092 O O   . ASN   A 1 306 ? -36.698 -33.814 5.475   1.00 49.50  ? 679 ASN   A O   1 
ATOM   2093 C CB  . ASN   A 1 306 ? -35.447 -36.432 4.600   1.00 60.36  ? 679 ASN   A CB  1 
ATOM   2094 C CG  . ASN   A 1 306 ? -35.920 -37.703 3.972   1.00 60.50  ? 679 ASN   A CG  1 
ATOM   2095 O OD1 . ASN   A 1 306 ? -37.109 -38.023 4.064   1.00 65.63  ? 679 ASN   A OD1 1 
ATOM   2096 N ND2 . ASN   A 1 306 ? -35.037 -38.355 3.239   1.00 59.48  ? 679 ASN   A ND2 1 
ATOM   2097 N N   . TYR   A 1 307 ? -34.970 -33.073 4.233   1.00 48.02  ? 680 TYR   A N   1 
ATOM   2098 C CA  . TYR   A 1 307 ? -34.815 -31.849 4.996   1.00 47.50  ? 680 TYR   A CA  1 
ATOM   2099 C C   . TYR   A 1 307 ? -34.636 -30.670 4.058   1.00 45.37  ? 680 TYR   A C   1 
ATOM   2100 O O   . TYR   A 1 307 ? -34.085 -30.821 2.961   1.00 45.49  ? 680 TYR   A O   1 
ATOM   2101 C CB  . TYR   A 1 307 ? -33.620 -32.003 5.928   1.00 50.33  ? 680 TYR   A CB  1 
ATOM   2102 C CG  . TYR   A 1 307 ? -33.848 -33.041 7.014   1.00 54.96  ? 680 TYR   A CG  1 
ATOM   2103 C CD1 . TYR   A 1 307 ? -34.511 -32.698 8.184   1.00 57.19  ? 680 TYR   A CD1 1 
ATOM   2104 C CD2 . TYR   A 1 307 ? -33.443 -34.367 6.858   1.00 58.37  ? 680 TYR   A CD2 1 
ATOM   2105 C CE1 . TYR   A 1 307 ? -34.773 -33.638 9.169   1.00 61.86  ? 680 TYR   A CE1 1 
ATOM   2106 C CE2 . TYR   A 1 307 ? -33.678 -35.314 7.850   1.00 60.69  ? 680 TYR   A CE2 1 
ATOM   2107 C CZ  . TYR   A 1 307 ? -34.355 -34.948 9.006   1.00 62.54  ? 680 TYR   A CZ  1 
ATOM   2108 O OH  . TYR   A 1 307 ? -34.615 -35.827 10.019  1.00 66.70  ? 680 TYR   A OH  1 
ATOM   2109 N N   . MET   A 1 308 ? -35.095 -29.493 4.513   1.00 45.02  ? 681 MET   A N   1 
ATOM   2110 C CA  . MET   A 1 308 ? -35.063 -28.293 3.695   1.00 41.54  ? 681 MET   A CA  1 
ATOM   2111 C C   . MET   A 1 308 ? -34.418 -27.141 4.459   1.00 41.61  ? 681 MET   A C   1 
ATOM   2112 O O   . MET   A 1 308 ? -34.793 -26.834 5.587   1.00 45.21  ? 681 MET   A O   1 
ATOM   2113 C CB  . MET   A 1 308 ? -36.464 -27.882 3.262   1.00 42.10  ? 681 MET   A CB  1 
ATOM   2114 C CG  . MET   A 1 308 ? -36.486 -26.593 2.437   1.00 42.59  ? 681 MET   A CG  1 
ATOM   2115 S SD  . MET   A 1 308 ? -38.153 -26.187 1.903   1.00 40.78  ? 681 MET   A SD  1 
ATOM   2116 C CE  . MET   A 1 308 ? -39.083 -25.903 3.408   1.00 44.91  ? 681 MET   A CE  1 
ATOM   2117 N N   . LEU   A 1 309 ? -33.448 -26.497 3.809   1.00 39.28  ? 682 LEU   A N   1 
ATOM   2118 C CA  . LEU   A 1 309 ? -32.830 -25.281 4.325   1.00 40.30  ? 682 LEU   A CA  1 
ATOM   2119 C C   . LEU   A 1 309 ? -33.515 -24.049 3.734   1.00 39.71  ? 682 LEU   A C   1 
ATOM   2120 O O   . LEU   A 1 309 ? -33.777 -24.018 2.533   1.00 36.38  ? 682 LEU   A O   1 
ATOM   2121 C CB  . LEU   A 1 309 ? -31.362 -25.351 3.929   1.00 39.13  ? 682 LEU   A CB  1 
ATOM   2122 C CG  . LEU   A 1 309 ? -30.513 -24.129 4.245   1.00 40.11  ? 682 LEU   A CG  1 
ATOM   2123 C CD1 . LEU   A 1 309 ? -30.324 -23.909 5.734   1.00 41.03  ? 682 LEU   A CD1 1 
ATOM   2124 C CD2 . LEU   A 1 309 ? -29.188 -24.299 3.523   1.00 40.22  ? 682 LEU   A CD2 1 
ATOM   2125 N N   . THR   A 1 310 ? -33.723 -23.029 4.590   1.00 40.99  ? 683 THR   A N   1 
ATOM   2126 C CA  . THR   A 1 310 ? -34.401 -21.777 4.252   1.00 39.05  ? 683 THR   A CA  1 
ATOM   2127 C C   . THR   A 1 310 ? -33.644 -20.623 4.890   1.00 40.35  ? 683 THR   A C   1 
ATOM   2128 O O   . THR   A 1 310 ? -32.854 -20.843 5.812   1.00 40.06  ? 683 THR   A O   1 
ATOM   2129 C CB  . THR   A 1 310 ? -35.843 -21.765 4.763   1.00 39.91  ? 683 THR   A CB  1 
ATOM   2130 O OG1 . THR   A 1 310 ? -35.740 -21.698 6.183   1.00 38.90  ? 683 THR   A OG1 1 
ATOM   2131 C CG2 . THR   A 1 310 ? -36.627 -22.991 4.346   1.00 41.53  ? 683 THR   A CG2 1 
ATOM   2132 N N   . CYS   A 1 311 ? -33.989 -19.390 4.462   1.00 41.01  ? 684 CYS   A N   1 
ATOM   2133 C CA  . CYS   A 1 311 ? -33.368 -18.171 4.973   1.00 40.54  ? 684 CYS   A CA  1 
ATOM   2134 C C   . CYS   A 1 311 ? -34.034 -17.720 6.276   1.00 43.67  ? 684 CYS   A C   1 
ATOM   2135 O O   . CYS   A 1 311 ? -35.200 -18.017 6.499   1.00 44.02  ? 684 CYS   A O   1 
ATOM   2136 C CB  . CYS   A 1 311 ? -33.512 -17.023 3.981   1.00 39.87  ? 684 CYS   A CB  1 
ATOM   2137 S SG  . CYS   A 1 311 ? -32.850 -17.361 2.324   1.00 36.62  ? 684 CYS   A SG  1 
ATOM   2138 N N   . SER   A 1 312 ? -33.276 -16.965 7.111   1.00 42.57  ? 685 SER   A N   1 
ATOM   2139 C CA  . SER   A 1 312 ? -33.824 -16.198 8.212   1.00 43.66  ? 685 SER   A CA  1 
ATOM   2140 C C   . SER   A 1 312 ? -32.915 -15.000 8.460   1.00 48.98  ? 685 SER   A C   1 
ATOM   2141 O O   . SER   A 1 312 ? -31.785 -14.972 7.973   1.00 51.59  ? 685 SER   A O   1 
ATOM   2142 C CB  . SER   A 1 312 ? -33.977 -17.030 9.491   1.00 45.33  ? 685 SER   A CB  1 
ATOM   2143 O OG  . SER   A 1 312 ? -32.768 -17.123 10.255  1.00 43.57  ? 685 SER   A OG  1 
ATOM   2144 N N   . ALA   A 1 313 ? -33.374 -14.068 9.307   1.00 48.77  ? 686 ALA   A N   1 
ATOM   2145 C CA  . ALA   A 1 313 ? -32.605 -12.879 9.617   1.00 50.53  ? 686 ALA   A CA  1 
ATOM   2146 C C   . ALA   A 1 313 ? -31.250 -13.283 10.205  1.00 51.68  ? 686 ALA   A C   1 
ATOM   2147 O O   . ALA   A 1 313 ? -30.257 -12.577 10.053  1.00 50.71  ? 686 ALA   A O   1 
ATOM   2148 C CB  . ALA   A 1 313 ? -33.398 -11.998 10.569  1.00 52.17  ? 686 ALA   A CB  1 
ATOM   2149 N N   . THR   A 1 314 ? -31.192 -14.456 10.825  1.00 50.31  ? 687 THR   A N   1 
ATOM   2150 C CA  . THR   A 1 314 ? -30.122 -14.715 11.763  1.00 53.89  ? 687 THR   A CA  1 
ATOM   2151 C C   . THR   A 1 314 ? -29.223 -15.856 11.279  1.00 53.10  ? 687 THR   A C   1 
ATOM   2152 O O   . THR   A 1 314 ? -28.147 -16.085 11.837  1.00 53.14  ? 687 THR   A O   1 
ATOM   2153 C CB  . THR   A 1 314 ? -30.797 -14.959 13.106  1.00 57.55  ? 687 THR   A CB  1 
ATOM   2154 O OG1 . THR   A 1 314 ? -30.002 -14.053 13.849  1.00 61.62  ? 687 THR   A OG1 1 
ATOM   2155 C CG2 . THR   A 1 314 ? -30.802 -16.402 13.566  1.00 59.67  ? 687 THR   A CG2 1 
ATOM   2156 N N   . GLY   A 1 315 ? -29.658 -16.535 10.208  1.00 48.67  ? 688 GLY   A N   1 
ATOM   2157 C CA  . GLY   A 1 315 ? -28.926 -17.644 9.638   1.00 46.81  ? 688 GLY   A CA  1 
ATOM   2158 C C   . GLY   A 1 315 ? -29.884 -18.660 9.029   1.00 45.61  ? 688 GLY   A C   1 
ATOM   2159 O O   . GLY   A 1 315 ? -31.097 -18.433 8.987   1.00 43.46  ? 688 GLY   A O   1 
ATOM   2160 N N   . GLY   A 1 316 ? -29.324 -19.795 8.599   1.00 48.10  ? 689 GLY   A N   1 
ATOM   2161 C CA  . GLY   A 1 316 ? -30.094 -20.838 7.932   1.00 47.29  ? 689 GLY   A CA  1 
ATOM   2162 C C   . GLY   A 1 316 ? -31.070 -21.519 8.894   1.00 47.84  ? 689 GLY   A C   1 
ATOM   2163 O O   . GLY   A 1 316 ? -30.755 -21.718 10.054  1.00 52.94  ? 689 GLY   A O   1 
ATOM   2164 N N   . VAL   A 1 317 ? -32.248 -21.896 8.395   1.00 46.11  ? 690 VAL   A N   1 
ATOM   2165 C CA  . VAL   A 1 317 ? -33.189 -22.647 9.195   1.00 46.39  ? 690 VAL   A CA  1 
ATOM   2166 C C   . VAL   A 1 317 ? -33.639 -23.876 8.419   1.00 44.53  ? 690 VAL   A C   1 
ATOM   2167 O O   . VAL   A 1 317 ? -34.084 -23.781 7.277   1.00 43.01  ? 690 VAL   A O   1 
ATOM   2168 C CB  . VAL   A 1 317 ? -34.369 -21.782 9.658   1.00 49.95  ? 690 VAL   A CB  1 
ATOM   2169 C CG1 . VAL   A 1 317 ? -35.431 -22.604 10.386  1.00 52.39  ? 690 VAL   A CG1 1 
ATOM   2170 C CG2 . VAL   A 1 317 ? -33.889 -20.619 10.533  1.00 48.73  ? 690 VAL   A CG2 1 
ATOM   2171 N N   . ILE   A 1 318 ? -33.518 -25.032 9.084   1.00 48.02  ? 691 ILE   A N   1 
ATOM   2172 C CA  . ILE   A 1 318 ? -33.709 -26.333 8.467   1.00 48.82  ? 691 ILE   A CA  1 
ATOM   2173 C C   . ILE   A 1 318 ? -34.954 -26.973 9.065   1.00 48.80  ? 691 ILE   A C   1 
ATOM   2174 O O   . ILE   A 1 318 ? -35.136 -26.969 10.276  1.00 52.75  ? 691 ILE   A O   1 
ATOM   2175 C CB  . ILE   A 1 318 ? -32.471 -27.235 8.647   1.00 50.55  ? 691 ILE   A CB  1 
ATOM   2176 C CG1 . ILE   A 1 318 ? -31.256 -26.683 7.926   1.00 47.89  ? 691 ILE   A CG1 1 
ATOM   2177 C CG2 . ILE   A 1 318 ? -32.770 -28.675 8.208   1.00 53.84  ? 691 ILE   A CG2 1 
ATOM   2178 C CD1 . ILE   A 1 318 ? -30.025 -27.568 8.018   1.00 47.56  ? 691 ILE   A CD1 1 
ATOM   2179 N N   . TYR   A 1 319 ? -35.784 -27.520 8.178   1.00 47.80  ? 692 TYR   A N   1 
ATOM   2180 C CA  . TYR   A 1 319 ? -37.013 -28.186 8.539   1.00 50.71  ? 692 TYR   A CA  1 
ATOM   2181 C C   . TYR   A 1 319 ? -37.030 -29.597 7.961   1.00 51.84  ? 692 TYR   A C   1 
ATOM   2182 O O   . TYR   A 1 319 ? -36.583 -29.824 6.833   1.00 52.50  ? 692 TYR   A O   1 
ATOM   2183 C CB  . TYR   A 1 319 ? -38.241 -27.490 7.952   1.00 49.96  ? 692 TYR   A CB  1 
ATOM   2184 C CG  . TYR   A 1 319 ? -38.475 -26.036 8.333   1.00 51.34  ? 692 TYR   A CG  1 
ATOM   2185 C CD1 . TYR   A 1 319 ? -39.265 -25.689 9.438   1.00 54.51  ? 692 TYR   A CD1 1 
ATOM   2186 C CD2 . TYR   A 1 319 ? -38.008 -25.007 7.519   1.00 48.13  ? 692 TYR   A CD2 1 
ATOM   2187 C CE1 . TYR   A 1 319 ? -39.524 -24.357 9.747   1.00 55.14  ? 692 TYR   A CE1 1 
ATOM   2188 C CE2 . TYR   A 1 319 ? -38.293 -23.682 7.798   1.00 49.38  ? 692 TYR   A CE2 1 
ATOM   2189 C CZ  . TYR   A 1 319 ? -39.045 -23.356 8.913   1.00 51.12  ? 692 TYR   A CZ  1 
ATOM   2190 O OH  . TYR   A 1 319 ? -39.277 -22.046 9.177   1.00 51.28  ? 692 TYR   A OH  1 
ATOM   2191 N N   . LYS   A 1 320 ? -37.695 -30.487 8.691   1.00 56.98  ? 693 LYS   A N   1 
ATOM   2192 C CA  . LYS   A 1 320 ? -38.012 -31.832 8.235   1.00 64.27  ? 693 LYS   A CA  1 
ATOM   2193 C C   . LYS   A 1 320 ? -39.245 -31.791 7.336   1.00 62.40  ? 693 LYS   A C   1 
ATOM   2194 O O   . LYS   A 1 320 ? -40.273 -31.256 7.723   1.00 65.84  ? 693 LYS   A O   1 
ATOM   2195 C CB  . LYS   A 1 320 ? -38.274 -32.741 9.446   1.00 68.98  ? 693 LYS   A CB  1 
ATOM   2196 C CG  . LYS   A 1 320 ? -38.432 -34.217 9.110   1.00 74.54  ? 693 LYS   A CG  1 
ATOM   2197 N N   . LEU   A 1 321 ? -39.122 -32.365 6.138   1.00 62.10  ? 694 LEU   A N   1 
ATOM   2198 C CA  . LEU   A 1 321 ? -40.241 -32.496 5.220   1.00 67.11  ? 694 LEU   A CA  1 
ATOM   2199 C C   . LEU   A 1 321 ? -40.992 -33.787 5.508   1.00 77.71  ? 694 LEU   A C   1 
ATOM   2200 O O   . LEU   A 1 321 ? -40.677 -34.474 6.472   1.00 79.06  ? 694 LEU   A O   1 
ATOM   2201 C CB  . LEU   A 1 321 ? -39.692 -32.490 3.799   1.00 60.97  ? 694 LEU   A CB  1 
ATOM   2202 C CG  . LEU   A 1 321 ? -38.904 -31.239 3.394   1.00 55.56  ? 694 LEU   A CG  1 
ATOM   2203 C CD1 . LEU   A 1 321 ? -38.383 -31.420 1.976   1.00 55.69  ? 694 LEU   A CD1 1 
ATOM   2204 C CD2 . LEU   A 1 321 ? -39.758 -30.003 3.509   1.00 52.64  ? 694 LEU   A CD2 1 
ATOM   2205 N N   . GLY   A 1 322 ? -41.963 -34.112 4.641   1.00 90.32  ? 695 GLY   A N   1 
ATOM   2206 C CA  . GLY   A 1 322 ? -42.599 -35.421 4.626   1.00 99.47  ? 695 GLY   A CA  1 
ATOM   2207 C C   . GLY   A 1 322 ? -43.857 -35.465 5.500   1.00 113.36 ? 695 GLY   A C   1 
ATOM   2208 O O   . GLY   A 1 322 ? -44.789 -36.210 5.202   1.00 126.54 ? 695 GLY   A O   1 
ATOM   2209 N N   . GLY   A 1 323 ? -43.867 -34.689 6.593   1.00 116.45 ? 696 GLY   A N   1 
ATOM   2210 C CA  . GLY   A 1 323 ? -45.030 -34.595 7.462   1.00 123.46 ? 696 GLY   A CA  1 
ATOM   2211 C C   . GLY   A 1 323 ? -46.229 -33.975 6.741   1.00 131.01 ? 696 GLY   A C   1 
ATOM   2212 O O   . GLY   A 1 323 ? -46.066 -33.151 5.837   1.00 133.12 ? 696 GLY   A O   1 
ATOM   2213 N N   . ASP   A 1 324 ? -47.431 -34.429 7.122   1.00 137.83 ? 697 ASP   A N   1 
ATOM   2214 C CA  . ASP   A 1 324 ? -48.662 -33.690 6.890   1.00 133.01 ? 697 ASP   A CA  1 
ATOM   2215 C C   . ASP   A 1 324 ? -49.156 -33.166 8.242   1.00 131.68 ? 697 ASP   A C   1 
ATOM   2216 O O   . ASP   A 1 324 ? -50.359 -33.145 8.496   1.00 145.63 ? 697 ASP   A O   1 
ATOM   2217 C CB  . ASP   A 1 324 ? -49.688 -34.534 6.137   1.00 125.69 ? 697 ASP   A CB  1 
ATOM   2218 N N   . GLU   A 1 325 ? -48.207 -32.769 9.113   1.00 113.31 ? 698 GLU   A N   1 
ATOM   2219 C CA  . GLU   A 1 325 ? -48.520 -32.112 10.375  1.00 107.85 ? 698 GLU   A CA  1 
ATOM   2220 C C   . GLU   A 1 325 ? -48.910 -30.653 10.104  1.00 109.94 ? 698 GLU   A C   1 
ATOM   2221 O O   . GLU   A 1 325 ? -48.608 -30.112 9.039   1.00 109.47 ? 698 GLU   A O   1 
ATOM   2222 C CB  . GLU   A 1 325 ? -47.326 -32.245 11.324  1.00 100.12 ? 698 GLU   A CB  1 
ATOM   2223 N N   . LYS   A 1 326 ? -49.579 -30.023 11.084  1.00 110.27 ? 699 LYS   A N   1 
ATOM   2224 C CA  . LYS   A 1 326 ? -50.207 -28.716 10.909  1.00 109.93 ? 699 LYS   A CA  1 
ATOM   2225 C C   . LYS   A 1 326 ? -49.137 -27.628 10.821  1.00 112.06 ? 699 LYS   A C   1 
ATOM   2226 O O   . LYS   A 1 326 ? -49.025 -26.952 9.802   1.00 102.59 ? 699 LYS   A O   1 
ATOM   2227 C CB  . LYS   A 1 326 ? -51.186 -28.418 12.055  1.00 113.56 ? 699 LYS   A CB  1 
ATOM   2228 N N   . VAL   A 1 327 ? -48.380 -27.441 11.917  1.00 119.74 ? 700 VAL   A N   1 
ATOM   2229 C CA  . VAL   A 1 327 ? -47.161 -26.640 11.893  1.00 114.68 ? 700 VAL   A CA  1 
ATOM   2230 C C   . VAL   A 1 327 ? -46.056 -27.472 11.234  1.00 110.70 ? 700 VAL   A C   1 
ATOM   2231 O O   . VAL   A 1 327 ? -46.137 -28.700 11.215  1.00 110.98 ? 700 VAL   A O   1 
ATOM   2232 C CB  . VAL   A 1 327 ? -46.754 -26.179 13.309  1.00 100.59 ? 700 VAL   A CB  1 
ATOM   2233 N N   . LEU   A 1 328 ? -45.037 -26.793 10.680  1.00 104.28 ? 701 LEU   A N   1 
ATOM   2234 C CA  . LEU   A 1 328 ? -43.893 -27.465 10.064  1.00 97.46  ? 701 LEU   A CA  1 
ATOM   2235 C C   . LEU   A 1 328 ? -42.762 -27.606 11.091  1.00 92.56  ? 701 LEU   A C   1 
ATOM   2236 O O   . LEU   A 1 328 ? -42.489 -26.667 11.850  1.00 88.77  ? 701 LEU   A O   1 
ATOM   2237 C CB  . LEU   A 1 328 ? -43.444 -26.678 8.831   1.00 95.57  ? 701 LEU   A CB  1 
ATOM   2238 C CG  . LEU   A 1 328 ? -42.467 -27.386 7.887   1.00 90.12  ? 701 LEU   A CG  1 
ATOM   2239 C CD1 . LEU   A 1 328 ? -43.074 -28.639 7.274   1.00 92.23  ? 701 LEU   A CD1 1 
ATOM   2240 C CD2 . LEU   A 1 328 ? -42.014 -26.425 6.805   1.00 84.94  ? 701 LEU   A CD2 1 
ATOM   2241 N N   . GLU   A 1 329 ? -42.104 -28.784 11.098  1.00 89.60  ? 702 GLU   A N   1 
ATOM   2242 C CA  . GLU   A 1 329 ? -41.251 -29.201 12.215  1.00 92.92  ? 702 GLU   A CA  1 
ATOM   2243 C C   . GLU   A 1 329 ? -39.847 -28.623 12.019  1.00 80.44  ? 702 GLU   A C   1 
ATOM   2244 O O   . GLU   A 1 329 ? -39.035 -29.178 11.262  1.00 78.92  ? 702 GLU   A O   1 
ATOM   2245 C CB  . GLU   A 1 329 ? -41.237 -30.725 12.424  1.00 91.52  ? 702 GLU   A CB  1 
ATOM   2246 N N   . SER   A 1 330 ? -39.596 -27.491 12.706  1.00 74.60  ? 703 SER   A N   1 
ATOM   2247 C CA  . SER   A 1 330 ? -38.324 -26.780 12.669  1.00 74.15  ? 703 SER   A CA  1 
ATOM   2248 C C   . SER   A 1 330 ? -37.309 -27.454 13.591  1.00 73.53  ? 703 SER   A C   1 
ATOM   2249 O O   . SER   A 1 330 ? -37.424 -27.319 14.804  1.00 77.79  ? 703 SER   A O   1 
ATOM   2250 C CB  . SER   A 1 330 ? -38.523 -25.333 13.069  1.00 75.66  ? 703 SER   A CB  1 
ATOM   2251 O OG  . SER   A 1 330 ? -37.274 -24.695 13.296  1.00 74.37  ? 703 SER   A OG  1 
ATOM   2252 N N   . CYS   A 1 331 ? -36.263 -28.081 13.017  1.00 71.16  ? 704 CYS   A N   1 
ATOM   2253 C CA  . CYS   A 1 331 ? -35.412 -28.983 13.789  1.00 72.84  ? 704 CYS   A CA  1 
ATOM   2254 C C   . CYS   A 1 331 ? -33.980 -28.455 13.999  1.00 68.66  ? 704 CYS   A C   1 
ATOM   2255 O O   . CYS   A 1 331 ? -33.343 -28.829 14.976  1.00 73.28  ? 704 CYS   A O   1 
ATOM   2256 C CB  . CYS   A 1 331 ? -35.418 -30.394 13.209  1.00 75.90  ? 704 CYS   A CB  1 
ATOM   2257 S SG  . CYS   A 1 331 ? -34.491 -30.549 11.665  1.00 72.40  ? 704 CYS   A SG  1 
ATOM   2258 N N   . LEU   A 1 332 ? -33.460 -27.581 13.128  1.00 63.74  ? 705 LEU   A N   1 
ATOM   2259 C CA  . LEU   A 1 332 ? -32.094 -27.104 13.317  1.00 62.44  ? 705 LEU   A CA  1 
ATOM   2260 C C   . LEU   A 1 332 ? -31.898 -25.693 12.747  1.00 58.90  ? 705 LEU   A C   1 
ATOM   2261 O O   . LEU   A 1 332 ? -32.398 -25.358 11.667  1.00 59.29  ? 705 LEU   A O   1 
ATOM   2262 C CB  . LEU   A 1 332 ? -31.145 -28.128 12.693  1.00 62.62  ? 705 LEU   A CB  1 
ATOM   2263 C CG  . LEU   A 1 332 ? -29.654 -27.784 12.710  1.00 63.63  ? 705 LEU   A CG  1 
ATOM   2264 C CD1 . LEU   A 1 332 ? -29.154 -27.606 14.112  1.00 70.43  ? 705 LEU   A CD1 1 
ATOM   2265 C CD2 . LEU   A 1 332 ? -28.862 -28.869 12.014  1.00 65.89  ? 705 LEU   A CD2 1 
ATOM   2266 N N   . SER   A 1 333 ? -31.149 -24.890 13.500  1.00 56.78  ? 706 SER   A N   1 
ATOM   2267 C CA  . SER   A 1 333 ? -30.851 -23.504 13.184  1.00 58.19  ? 706 SER   A CA  1 
ATOM   2268 C C   . SER   A 1 333 ? -29.339 -23.329 13.130  1.00 59.04  ? 706 SER   A C   1 
ATOM   2269 O O   . SER   A 1 333 ? -28.669 -23.595 14.125  1.00 63.34  ? 706 SER   A O   1 
ATOM   2270 C CB  . SER   A 1 333 ? -31.438 -22.571 14.223  1.00 59.55  ? 706 SER   A CB  1 
ATOM   2271 O OG  . SER   A 1 333 ? -32.849 -22.481 14.093  1.00 61.50  ? 706 SER   A OG  1 
ATOM   2272 N N   . LEU   A 1 334 ? -28.811 -22.861 11.990  1.00 53.80  ? 707 LEU   A N   1 
ATOM   2273 C CA  . LEU   A 1 334 ? -27.371 -22.868 11.777  1.00 52.84  ? 707 LEU   A CA  1 
ATOM   2274 C C   . LEU   A 1 334 ? -26.711 -21.627 12.379  1.00 53.05  ? 707 LEU   A C   1 
ATOM   2275 O O   . LEU   A 1 334 ? -25.528 -21.671 12.705  1.00 52.27  ? 707 LEU   A O   1 
ATOM   2276 C CB  . LEU   A 1 334 ? -27.067 -23.005 10.292  1.00 52.70  ? 707 LEU   A CB  1 
ATOM   2277 C CG  . LEU   A 1 334 ? -27.641 -24.245 9.610   1.00 54.96  ? 707 LEU   A CG  1 
ATOM   2278 C CD1 . LEU   A 1 334 ? -27.148 -24.355 8.197   1.00 52.57  ? 707 LEU   A CD1 1 
ATOM   2279 C CD2 . LEU   A 1 334 ? -27.298 -25.505 10.404  1.00 57.27  ? 707 LEU   A CD2 1 
ATOM   2280 N N   . GLY   A 1 335 ? -27.451 -20.505 12.456  1.00 54.45  ? 708 GLY   A N   1 
ATOM   2281 C CA  . GLY   A 1 335 ? -26.961 -19.286 13.106  1.00 54.35  ? 708 GLY   A CA  1 
ATOM   2282 C C   . GLY   A 1 335 ? -25.753 -18.666 12.384  1.00 54.71  ? 708 GLY   A C   1 
ATOM   2283 O O   . GLY   A 1 335 ? -25.409 -19.046 11.261  1.00 51.58  ? 708 GLY   A O   1 
ATOM   2284 N N   . GLY   A 1 336 ? -25.135 -17.666 13.033  1.00 58.43  ? 709 GLY   A N   1 
ATOM   2285 C CA  . GLY   A 1 336 ? -23.832 -17.148 12.626  1.00 57.34  ? 709 GLY   A CA  1 
ATOM   2286 C C   . GLY   A 1 336 ? -23.923 -15.909 11.724  1.00 57.06  ? 709 GLY   A C   1 
ATOM   2287 O O   . GLY   A 1 336 ? -22.906 -15.426 11.246  1.00 56.21  ? 709 GLY   A O   1 
ATOM   2288 N N   . HIS   A 1 337 ? -25.133 -15.410 11.456  1.00 56.17  ? 710 HIS   A N   1 
ATOM   2289 C CA  . HIS   A 1 337 ? -25.280 -14.259 10.575  1.00 55.34  ? 710 HIS   A CA  1 
ATOM   2290 C C   . HIS   A 1 337 ? -25.771 -13.060 11.384  1.00 59.41  ? 710 HIS   A C   1 
ATOM   2291 O O   . HIS   A 1 337 ? -26.707 -13.206 12.165  1.00 59.12  ? 710 HIS   A O   1 
ATOM   2292 C CB  . HIS   A 1 337 ? -26.213 -14.580 9.401   1.00 50.78  ? 710 HIS   A CB  1 
ATOM   2293 C CG  . HIS   A 1 337 ? -25.623 -15.470 8.353   1.00 46.17  ? 710 HIS   A CG  1 
ATOM   2294 N ND1 . HIS   A 1 337 ? -24.893 -14.982 7.291   1.00 42.79  ? 710 HIS   A ND1 1 
ATOM   2295 C CD2 . HIS   A 1 337 ? -25.664 -16.812 8.200   1.00 44.37  ? 710 HIS   A CD2 1 
ATOM   2296 C CE1 . HIS   A 1 337 ? -24.508 -16.007 6.521   1.00 45.21  ? 710 HIS   A CE1 1 
ATOM   2297 N NE2 . HIS   A 1 337 ? -24.971 -17.137 7.051   1.00 42.40  ? 710 HIS   A NE2 1 
ATOM   2298 N N   . ARG   A 1 338 ? -25.132 -11.890 11.156  1.00 60.51  ? 711 ARG   A N   1 
ATOM   2299 C CA  . ARG   A 1 338 ? -25.486 -10.619 11.792  1.00 65.98  ? 711 ARG   A CA  1 
ATOM   2300 C C   . ARG   A 1 338 ? -26.223 -9.710  10.791  1.00 62.53  ? 711 ARG   A C   1 
ATOM   2301 O O   . ARG   A 1 338 ? -26.462 -8.537  11.052  1.00 61.25  ? 711 ARG   A O   1 
ATOM   2302 C CB  . ARG   A 1 338 ? -24.225 -9.897  12.311  1.00 70.51  ? 711 ARG   A CB  1 
ATOM   2303 C CG  . ARG   A 1 338 ? -23.288 -10.705 13.206  1.00 72.85  ? 711 ARG   A CG  1 
ATOM   2304 N N   . ALA   A 1 339 ? -26.556 -10.259 9.626   1.00 57.46  ? 712 ALA   A N   1 
ATOM   2305 C CA  . ALA   A 1 339 ? -27.309 -9.551  8.611   1.00 55.16  ? 712 ALA   A CA  1 
ATOM   2306 C C   . ALA   A 1 339 ? -28.193 -10.559 7.899   1.00 51.06  ? 712 ALA   A C   1 
ATOM   2307 O O   . ALA   A 1 339 ? -27.873 -11.739 7.930   1.00 50.48  ? 712 ALA   A O   1 
ATOM   2308 C CB  . ALA   A 1 339 ? -26.350 -8.892  7.662   1.00 58.21  ? 712 ALA   A CB  1 
ATOM   2309 N N   . PRO   A 1 340 ? -29.346 -10.168 7.295   1.00 50.00  ? 713 PRO   A N   1 
ATOM   2310 C CA  . PRO   A 1 340 ? -30.269 -11.136 6.696   1.00 49.76  ? 713 PRO   A CA  1 
ATOM   2311 C C   . PRO   A 1 340 ? -29.647 -12.086 5.680   1.00 45.02  ? 713 PRO   A C   1 
ATOM   2312 O O   . PRO   A 1 340 ? -28.835 -11.673 4.853   1.00 42.89  ? 713 PRO   A O   1 
ATOM   2313 C CB  . PRO   A 1 340 ? -31.351 -10.236 6.072   1.00 48.13  ? 713 PRO   A CB  1 
ATOM   2314 C CG  . PRO   A 1 340 ? -31.412 -9.096  7.046   1.00 51.02  ? 713 PRO   A CG  1 
ATOM   2315 C CD  . PRO   A 1 340 ? -29.928 -8.822  7.322   1.00 53.61  ? 713 PRO   A CD  1 
ATOM   2316 N N   . VAL   A 1 341 ? -30.008 -13.372 5.820   1.00 43.58  ? 714 VAL   A N   1 
ATOM   2317 C CA  . VAL   A 1 341 ? -29.683 -14.401 4.842   1.00 40.26  ? 714 VAL   A CA  1 
ATOM   2318 C C   . VAL   A 1 341 ? -30.683 -14.272 3.713   1.00 38.88  ? 714 VAL   A C   1 
ATOM   2319 O O   . VAL   A 1 341 ? -31.874 -14.197 3.962   1.00 39.86  ? 714 VAL   A O   1 
ATOM   2320 C CB  . VAL   A 1 341 ? -29.707 -15.822 5.444   1.00 40.21  ? 714 VAL   A CB  1 
ATOM   2321 C CG1 . VAL   A 1 341 ? -29.453 -16.920 4.405   1.00 40.44  ? 714 VAL   A CG1 1 
ATOM   2322 C CG2 . VAL   A 1 341 ? -28.707 -15.950 6.557   1.00 43.43  ? 714 VAL   A CG2 1 
ATOM   2323 N N   . VAL   A 1 342 ? -30.187 -14.270 2.479   1.00 38.77  ? 715 VAL   A N   1 
ATOM   2324 C CA  . VAL   A 1 342 ? -31.035 -13.980 1.327   1.00 38.27  ? 715 VAL   A CA  1 
ATOM   2325 C C   . VAL   A 1 342 ? -30.977 -15.098 0.295   1.00 35.79  ? 715 VAL   A C   1 
ATOM   2326 O O   . VAL   A 1 342 ? -31.751 -15.068 -0.647  1.00 34.75  ? 715 VAL   A O   1 
ATOM   2327 C CB  . VAL   A 1 342 ? -30.624 -12.655 0.666   1.00 37.90  ? 715 VAL   A CB  1 
ATOM   2328 C CG1 . VAL   A 1 342 ? -30.758 -11.500 1.624   1.00 41.98  ? 715 VAL   A CG1 1 
ATOM   2329 C CG2 . VAL   A 1 342 ? -29.211 -12.723 0.109   1.00 38.45  ? 715 VAL   A CG2 1 
ATOM   2330 N N   . THR   A 1 343 ? -30.024 -16.039 0.421   1.00 37.48  ? 716 THR   A N   1 
ATOM   2331 C CA  . THR   A 1 343 ? -30.006 -17.204 -0.456  1.00 34.59  ? 716 THR   A CA  1 
ATOM   2332 C C   . THR   A 1 343 ? -29.194 -18.308 0.214   1.00 36.43  ? 716 THR   A C   1 
ATOM   2333 O O   . THR   A 1 343 ? -28.395 -18.047 1.133   1.00 37.36  ? 716 THR   A O   1 
ATOM   2334 C CB  . THR   A 1 343 ? -29.493 -16.824 -1.860  1.00 35.79  ? 716 THR   A CB  1 
ATOM   2335 O OG1 . THR   A 1 343 ? -29.703 -17.913 -2.758  1.00 37.53  ? 716 THR   A OG1 1 
ATOM   2336 C CG2 . THR   A 1 343 ? -28.021 -16.458 -1.883  1.00 37.02  ? 716 THR   A CG2 1 
ATOM   2337 N N   . VAL   A 1 344 ? -29.467 -19.556 -0.187  1.00 34.03  ? 717 VAL   A N   1 
ATOM   2338 C CA  . VAL   A 1 344 ? -28.867 -20.700 0.466   1.00 35.92  ? 717 VAL   A CA  1 
ATOM   2339 C C   . VAL   A 1 344 ? -28.489 -21.742 -0.580  1.00 37.46  ? 717 VAL   A C   1 
ATOM   2340 O O   . VAL   A 1 344 ? -28.895 -21.627 -1.732  1.00 34.61  ? 717 VAL   A O   1 
ATOM   2341 C CB  . VAL   A 1 344 ? -29.839 -21.290 1.483   1.00 36.89  ? 717 VAL   A CB  1 
ATOM   2342 C CG1 . VAL   A 1 344 ? -30.159 -20.318 2.598   1.00 38.53  ? 717 VAL   A CG1 1 
ATOM   2343 C CG2 . VAL   A 1 344 ? -31.108 -21.782 0.817   1.00 37.19  ? 717 VAL   A CG2 1 
ATOM   2344 N N   . ASP   A 1 345 ? -27.682 -22.734 -0.165  1.00 36.33  ? 718 ASP   A N   1 
ATOM   2345 C CA  . ASP   A 1 345 ? -27.528 -23.958 -0.926  1.00 37.35  ? 718 ASP   A CA  1 
ATOM   2346 C C   . ASP   A 1 345 ? -27.242 -25.128 0.023   1.00 39.02  ? 718 ASP   A C   1 
ATOM   2347 O O   . ASP   A 1 345 ? -26.889 -24.915 1.165   1.00 36.64  ? 718 ASP   A O   1 
ATOM   2348 C CB  . ASP   A 1 345 ? -26.440 -23.806 -1.973  1.00 39.98  ? 718 ASP   A CB  1 
ATOM   2349 C CG  . ASP   A 1 345 ? -26.542 -24.738 -3.171  1.00 38.23  ? 718 ASP   A CG  1 
ATOM   2350 O OD1 . ASP   A 1 345 ? -27.592 -25.398 -3.319  1.00 37.85  ? 718 ASP   A OD1 1 
ATOM   2351 O OD2 . ASP   A 1 345 ? -25.587 -24.766 -3.961  1.00 40.64  ? 718 ASP   A OD2 1 
ATOM   2352 N N   . TRP   A 1 346 ? -27.363 -26.356 -0.494  1.00 38.72  ? 719 TRP   A N   1 
ATOM   2353 C CA  . TRP   A 1 346 ? -27.070 -27.571 0.265   1.00 40.57  ? 719 TRP   A CA  1 
ATOM   2354 C C   . TRP   A 1 346 ? -26.539 -28.636 -0.695  1.00 39.74  ? 719 TRP   A C   1 
ATOM   2355 O O   . TRP   A 1 346 ? -27.255 -29.013 -1.619  1.00 38.58  ? 719 TRP   A O   1 
ATOM   2356 C CB  . TRP   A 1 346 ? -28.355 -28.063 0.934   1.00 38.70  ? 719 TRP   A CB  1 
ATOM   2357 C CG  . TRP   A 1 346 ? -28.154 -29.023 2.059   1.00 39.07  ? 719 TRP   A CG  1 
ATOM   2358 C CD1 . TRP   A 1 346 ? -27.071 -29.825 2.322   1.00 39.90  ? 719 TRP   A CD1 1 
ATOM   2359 C CD2 . TRP   A 1 346 ? -29.109 -29.276 3.111   1.00 38.31  ? 719 TRP   A CD2 1 
ATOM   2360 N NE1 . TRP   A 1 346 ? -27.278 -30.521 3.485   1.00 38.88  ? 719 TRP   A NE1 1 
ATOM   2361 C CE2 . TRP   A 1 346 ? -28.514 -30.212 3.988   1.00 39.19  ? 719 TRP   A CE2 1 
ATOM   2362 C CE3 . TRP   A 1 346 ? -30.386 -28.792 3.399   1.00 36.89  ? 719 TRP   A CE3 1 
ATOM   2363 C CZ2 . TRP   A 1 346 ? -29.165 -30.669 5.130   1.00 43.21  ? 719 TRP   A CZ2 1 
ATOM   2364 C CZ3 . TRP   A 1 346 ? -31.009 -29.209 4.553   1.00 38.68  ? 719 TRP   A CZ3 1 
ATOM   2365 C CH2 . TRP   A 1 346 ? -30.424 -30.173 5.385   1.00 41.77  ? 719 TRP   A CH2 1 
ATOM   2366 N N   . SER   A 1 347 ? -25.277 -29.042 -0.527  1.00 41.41  ? 720 SER   A N   1 
ATOM   2367 C CA  . SER   A 1 347 ? -24.695 -30.096 -1.351  1.00 48.06  ? 720 SER   A CA  1 
ATOM   2368 C C   . SER   A 1 347 ? -24.246 -31.254 -0.466  1.00 50.16  ? 720 SER   A C   1 
ATOM   2369 O O   . SER   A 1 347 ? -23.893 -31.051 0.689   1.00 46.83  ? 720 SER   A O   1 
ATOM   2370 C CB  . SER   A 1 347 ? -23.541 -29.607 -2.173  1.00 49.72  ? 720 SER   A CB  1 
ATOM   2371 O OG  . SER   A 1 347 ? -23.075 -30.637 -3.040  1.00 54.39  ? 720 SER   A OG  1 
ATOM   2372 N N   . THR   A 1 348 ? -24.309 -32.473 -1.008  1.00 59.11  ? 721 THR   A N   1 
ATOM   2373 C CA  . THR   A 1 348 ? -23.982 -33.669 -0.229  1.00 69.18  ? 721 THR   A CA  1 
ATOM   2374 C C   . THR   A 1 348 ? -23.028 -34.524 -1.051  1.00 70.39  ? 721 THR   A C   1 
ATOM   2375 O O   . THR   A 1 348 ? -23.339 -34.899 -2.182  1.00 65.17  ? 721 THR   A O   1 
ATOM   2376 C CB  . THR   A 1 348 ? -25.231 -34.448 0.222   1.00 66.22  ? 721 THR   A CB  1 
ATOM   2377 O OG1 . THR   A 1 348 ? -26.079 -34.582 -0.909  1.00 76.91  ? 721 THR   A OG1 1 
ATOM   2378 C CG2 . THR   A 1 348 ? -26.034 -33.738 1.302   1.00 60.57  ? 721 THR   A CG2 1 
ATOM   2379 N N   . ALA   A 1 349 ? -21.855 -34.784 -0.452  1.00 82.73  ? 722 ALA   A N   1 
ATOM   2380 C CA  . ALA   A 1 349 ? -20.716 -35.402 -1.120  1.00 85.84  ? 722 ALA   A CA  1 
ATOM   2381 C C   . ALA   A 1 349 ? -19.826 -36.070 -0.075  1.00 89.99  ? 722 ALA   A C   1 
ATOM   2382 O O   . ALA   A 1 349 ? -19.625 -35.530 1.014   1.00 81.70  ? 722 ALA   A O   1 
ATOM   2383 C CB  . ALA   A 1 349 ? -19.944 -34.356 -1.906  1.00 83.42  ? 722 ALA   A CB  1 
ATOM   2384 N N   . MET   A 1 350 ? -19.286 -37.244 -0.417  1.00 99.49  ? 723 MET   A N   1 
ATOM   2385 C CA  . MET   A 1 350 ? -18.476 -38.017 0.515   1.00 101.33 ? 723 MET   A CA  1 
ATOM   2386 C C   . MET   A 1 350 ? -19.302 -38.307 1.781   1.00 105.43 ? 723 MET   A C   1 
ATOM   2387 O O   . MET   A 1 350 ? -18.770 -38.263 2.888   1.00 110.65 ? 723 MET   A O   1 
ATOM   2388 C CB  . MET   A 1 350 ? -17.174 -37.270 0.876   1.00 100.94 ? 723 MET   A CB  1 
ATOM   2389 C CG  . MET   A 1 350 ? -16.373 -36.684 -0.317  1.00 104.60 ? 723 MET   A CG  1 
ATOM   2390 S SD  . MET   A 1 350 ? -15.028 -37.705 -0.982  1.00 108.84 ? 723 MET   A SD  1 
ATOM   2391 C CE  . MET   A 1 350 ? -14.162 -36.583 -2.095  1.00 107.50 ? 723 MET   A CE  1 
ATOM   2392 N N   . ASP   A 1 351 ? -20.613 -38.580 1.605   1.00 105.81 ? 724 ASP   A N   1 
ATOM   2393 C CA  . ASP   A 1 351 ? -21.503 -38.975 2.697   1.00 102.41 ? 724 ASP   A CA  1 
ATOM   2394 C C   . ASP   A 1 351 ? -21.552 -37.879 3.770   1.00 97.65  ? 724 ASP   A C   1 
ATOM   2395 O O   . ASP   A 1 351 ? -21.629 -38.174 4.961   1.00 112.59 ? 724 ASP   A O   1 
ATOM   2396 C CB  . ASP   A 1 351 ? -21.108 -40.335 3.262   1.00 101.11 ? 724 ASP   A CB  1 
ATOM   2397 N N   . CYS   A 1 352 ? -21.547 -36.613 3.326   1.00 88.73  ? 725 CYS   A N   1 
ATOM   2398 C CA  . CYS   A 1 352 ? -21.384 -35.458 4.200   1.00 78.38  ? 725 CYS   A CA  1 
ATOM   2399 C C   . CYS   A 1 352 ? -22.037 -34.219 3.577   1.00 61.57  ? 725 CYS   A C   1 
ATOM   2400 O O   . CYS   A 1 352 ? -22.002 -34.038 2.369   1.00 61.39  ? 725 CYS   A O   1 
ATOM   2401 C CB  . CYS   A 1 352 ? -19.906 -35.197 4.457   1.00 83.29  ? 725 CYS   A CB  1 
ATOM   2402 S SG  . CYS   A 1 352 ? -19.561 -33.518 5.042   1.00 82.11  ? 725 CYS   A SG  1 
ATOM   2403 N N   . GLY   A 1 353 ? -22.614 -33.357 4.414   1.00 57.42  ? 726 GLY   A N   1 
ATOM   2404 C CA  . GLY   A 1 353 ? -23.442 -32.251 3.939   1.00 57.15  ? 726 GLY   A CA  1 
ATOM   2405 C C   . GLY   A 1 353 ? -22.734 -30.895 4.063   1.00 55.98  ? 726 GLY   A C   1 
ATOM   2406 O O   . GLY   A 1 353 ? -22.135 -30.582 5.092   1.00 56.03  ? 726 GLY   A O   1 
ATOM   2407 N N   . THR   A 1 354 ? -22.858 -30.074 3.014   1.00 52.89  ? 727 THR   A N   1 
ATOM   2408 C CA  . THR   A 1 354 ? -22.322 -28.721 3.003   1.00 52.44  ? 727 THR   A CA  1 
ATOM   2409 C C   . THR   A 1 354 ? -23.468 -27.709 2.832   1.00 47.05  ? 727 THR   A C   1 
ATOM   2410 O O   . THR   A 1 354 ? -24.116 -27.679 1.791   1.00 43.66  ? 727 THR   A O   1 
ATOM   2411 C CB  . THR   A 1 354 ? -21.312 -28.628 1.854   1.00 54.74  ? 727 THR   A CB  1 
ATOM   2412 O OG1 . THR   A 1 354 ? -20.224 -29.509 2.133   1.00 58.84  ? 727 THR   A OG1 1 
ATOM   2413 C CG2 . THR   A 1 354 ? -20.755 -27.226 1.696   1.00 58.42  ? 727 THR   A CG2 1 
ATOM   2414 N N   . CYS   A 1 355 ? -23.703 -26.857 3.836   1.00 44.79  ? 728 CYS   A N   1 
ATOM   2415 C CA  . CYS   A 1 355 ? -24.740 -25.833 3.722   1.00 44.82  ? 728 CYS   A CA  1 
ATOM   2416 C C   . CYS   A 1 355 ? -24.141 -24.432 3.557   1.00 41.69  ? 728 CYS   A C   1 
ATOM   2417 O O   . CYS   A 1 355 ? -23.357 -23.985 4.395   1.00 42.43  ? 728 CYS   A O   1 
ATOM   2418 C CB  . CYS   A 1 355 ? -25.662 -25.843 4.938   1.00 48.68  ? 728 CYS   A CB  1 
ATOM   2419 S SG  . CYS   A 1 355 ? -26.477 -27.443 5.199   1.00 46.84  ? 728 CYS   A SG  1 
ATOM   2420 N N   . LEU   A 1 356 ? -24.615 -23.715 2.534   1.00 39.10  ? 729 LEU   A N   1 
ATOM   2421 C CA  . LEU   A 1 356 ? -24.267 -22.322 2.327   1.00 40.30  ? 729 LEU   A CA  1 
ATOM   2422 C C   . LEU   A 1 356 ? -25.414 -21.428 2.779   1.00 40.32  ? 729 LEU   A C   1 
ATOM   2423 O O   . LEU   A 1 356 ? -26.557 -21.607 2.364   1.00 40.03  ? 729 LEU   A O   1 
ATOM   2424 C CB  . LEU   A 1 356 ? -23.949 -22.058 0.859   1.00 41.97  ? 729 LEU   A CB  1 
ATOM   2425 C CG  . LEU   A 1 356 ? -22.846 -22.915 0.252   1.00 46.52  ? 729 LEU   A CG  1 
ATOM   2426 C CD1 . LEU   A 1 356 ? -22.582 -22.446 -1.159  1.00 50.68  ? 729 LEU   A CD1 1 
ATOM   2427 C CD2 . LEU   A 1 356 ? -21.603 -22.854 1.080   1.00 51.65  ? 729 LEU   A CD2 1 
ATOM   2428 N N   . THR   A 1 357 ? -25.074 -20.434 3.609   1.00 41.31  ? 730 THR   A N   1 
ATOM   2429 C CA  . THR   A 1 357 ? -25.978 -19.344 3.916   1.00 41.51  ? 730 THR   A CA  1 
ATOM   2430 C C   . THR   A 1 357 ? -25.259 -18.022 3.635   1.00 41.30  ? 730 THR   A C   1 
ATOM   2431 O O   . THR   A 1 357 ? -24.109 -17.832 4.050   1.00 40.78  ? 730 THR   A O   1 
ATOM   2432 C CB  . THR   A 1 357 ? -26.453 -19.468 5.362   1.00 41.91  ? 730 THR   A CB  1 
ATOM   2433 O OG1 . THR   A 1 357 ? -25.288 -19.449 6.177   1.00 44.11  ? 730 THR   A OG1 1 
ATOM   2434 C CG2 . THR   A 1 357 ? -27.236 -20.737 5.588   1.00 42.27  ? 730 THR   A CG2 1 
ATOM   2435 N N   . ALA   A 1 358 ? -25.960 -17.134 2.913   1.00 40.29  ? 731 ALA   A N   1 
ATOM   2436 C CA  . ALA   A 1 358 ? -25.382 -15.920 2.361   1.00 40.07  ? 731 ALA   A CA  1 
ATOM   2437 C C   . ALA   A 1 358 ? -26.242 -14.725 2.748   1.00 39.96  ? 731 ALA   A C   1 
ATOM   2438 O O   . ALA   A 1 358 ? -27.456 -14.748 2.579   1.00 38.01  ? 731 ALA   A O   1 
ATOM   2439 C CB  . ALA   A 1 358 ? -25.253 -16.031 0.869   1.00 39.45  ? 731 ALA   A CB  1 
ATOM   2440 N N   . SER   A 1 359 ? -25.583 -13.690 3.269   1.00 41.63  ? 732 SER   A N   1 
ATOM   2441 C CA  . SER   A 1 359 ? -26.253 -12.585 3.928   1.00 42.28  ? 732 SER   A CA  1 
ATOM   2442 C C   . SER   A 1 359 ? -25.949 -11.248 3.230   1.00 45.30  ? 732 SER   A C   1 
ATOM   2443 O O   . SER   A 1 359 ? -25.074 -11.146 2.368   1.00 45.83  ? 732 SER   A O   1 
ATOM   2444 C CB  . SER   A 1 359 ? -25.843 -12.551 5.374   1.00 45.44  ? 732 SER   A CB  1 
ATOM   2445 O OG  . SER   A 1 359 ? -24.423 -12.573 5.513   1.00 45.98  ? 732 SER   A OG  1 
ATOM   2446 N N   . MET   A 1 360 ? -26.652 -10.208 3.666   1.00 45.53  ? 733 MET   A N   1 
ATOM   2447 C CA  . MET   A 1 360 ? -26.687 -8.934  2.974   1.00 48.06  ? 733 MET   A CA  1 
ATOM   2448 C C   . MET   A 1 360 ? -25.412 -8.117  3.187   1.00 50.64  ? 733 MET   A C   1 
ATOM   2449 O O   . MET   A 1 360 ? -25.145 -7.206  2.421   1.00 51.40  ? 733 MET   A O   1 
ATOM   2450 C CB  . MET   A 1 360 ? -27.897 -8.124  3.438   1.00 47.31  ? 733 MET   A CB  1 
ATOM   2451 C CG  . MET   A 1 360 ? -29.172 -8.714  2.943   1.00 44.37  ? 733 MET   A CG  1 
ATOM   2452 S SD  . MET   A 1 360 ? -30.567 -7.654  3.321   1.00 45.88  ? 733 MET   A SD  1 
ATOM   2453 C CE  . MET   A 1 360 ? -30.395 -6.231  2.211   1.00 46.84  ? 733 MET   A CE  1 
ATOM   2454 N N   . ASP   A 1 361 ? -24.608 -8.501  4.180   1.00 51.63  ? 734 ASP   A N   1 
ATOM   2455 C CA  . ASP   A 1 361 ? -23.286 -7.931  4.417   1.00 51.05  ? 734 ASP   A CA  1 
ATOM   2456 C C   . ASP   A 1 361 ? -22.222 -8.560  3.499   1.00 50.29  ? 734 ASP   A C   1 
ATOM   2457 O O   . ASP   A 1 361 ? -21.053 -8.281  3.663   1.00 52.92  ? 734 ASP   A O   1 
ATOM   2458 C CB  . ASP   A 1 361 ? -22.880 -8.145  5.870   1.00 51.36  ? 734 ASP   A CB  1 
ATOM   2459 C CG  . ASP   A 1 361 ? -23.005 -9.594  6.343   1.00 51.29  ? 734 ASP   A CG  1 
ATOM   2460 O OD1 . ASP   A 1 361 ? -23.265 -10.453 5.481   1.00 49.75  ? 734 ASP   A OD1 1 
ATOM   2461 O OD2 . ASP   A 1 361 ? -22.941 -9.848  7.565   1.00 52.23  ? 734 ASP   A OD2 1 
ATOM   2462 N N   . GLY   A 1 362 ? -22.602 -9.480  2.598   1.00 49.90  ? 735 GLY   A N   1 
ATOM   2463 C CA  . GLY   A 1 362 ? -21.641 -10.134 1.710   1.00 49.32  ? 735 GLY   A CA  1 
ATOM   2464 C C   . GLY   A 1 362 ? -21.047 -11.433 2.291   1.00 49.36  ? 735 GLY   A C   1 
ATOM   2465 O O   . GLY   A 1 362 ? -20.278 -12.135 1.617   1.00 48.49  ? 735 GLY   A O   1 
ATOM   2466 N N   . LYS   A 1 363 ? -21.411 -11.775 3.525   1.00 49.04  ? 736 LYS   A N   1 
ATOM   2467 C CA  . LYS   A 1 363 ? -20.813 -12.917 4.196   1.00 49.91  ? 736 LYS   A CA  1 
ATOM   2468 C C   . LYS   A 1 363 ? -21.517 -14.205 3.775   1.00 46.72  ? 736 LYS   A C   1 
ATOM   2469 O O   . LYS   A 1 363 ? -22.732 -14.234 3.595   1.00 47.83  ? 736 LYS   A O   1 
ATOM   2470 C CB  . LYS   A 1 363 ? -20.849 -12.707 5.704   1.00 51.97  ? 736 LYS   A CB  1 
ATOM   2471 C CG  . LYS   A 1 363 ? -19.803 -11.756 6.202   1.00 55.07  ? 736 LYS   A CG  1 
ATOM   2472 C CD  . LYS   A 1 363 ? -19.977 -11.343 7.656   1.00 60.18  ? 736 LYS   A CD  1 
ATOM   2473 N N   . ILE   A 1 364 ? -20.720 -15.256 3.584   1.00 45.07  ? 737 ILE   A N   1 
ATOM   2474 C CA  . ILE   A 1 364 ? -21.236 -16.584 3.303   1.00 44.53  ? 737 ILE   A CA  1 
ATOM   2475 C C   . ILE   A 1 364 ? -20.704 -17.552 4.349   1.00 47.42  ? 737 ILE   A C   1 
ATOM   2476 O O   . ILE   A 1 364 ? -19.499 -17.659 4.541   1.00 50.17  ? 737 ILE   A O   1 
ATOM   2477 C CB  . ILE   A 1 364 ? -20.836 -17.040 1.890   1.00 44.73  ? 737 ILE   A CB  1 
ATOM   2478 C CG1 . ILE   A 1 364 ? -21.376 -16.100 0.813   1.00 40.82  ? 737 ILE   A CG1 1 
ATOM   2479 C CG2 . ILE   A 1 364 ? -21.261 -18.492 1.638   1.00 42.75  ? 737 ILE   A CG2 1 
ATOM   2480 C CD1 . ILE   A 1 364 ? -20.789 -16.344 -0.564  1.00 40.01  ? 737 ILE   A CD1 1 
ATOM   2481 N N   . LYS   A 1 365 ? -21.619 -18.220 5.047   1.00 48.02  ? 738 LYS   A N   1 
ATOM   2482 C CA  . LYS   A 1 365 ? -21.249 -19.216 6.026   1.00 48.90  ? 738 LYS   A CA  1 
ATOM   2483 C C   . LYS   A 1 365 ? -21.346 -20.584 5.361   1.00 49.37  ? 738 LYS   A C   1 
ATOM   2484 O O   . LYS   A 1 365 ? -22.349 -20.903 4.715   1.00 44.82  ? 738 LYS   A O   1 
ATOM   2485 C CB  . LYS   A 1 365 ? -22.130 -19.191 7.283   1.00 49.77  ? 738 LYS   A CB  1 
ATOM   2486 C CG  . LYS   A 1 365 ? -21.819 -18.106 8.309   1.00 55.03  ? 738 LYS   A CG  1 
ATOM   2487 C CD  . LYS   A 1 365 ? -20.335 -17.795 8.477   1.00 59.85  ? 738 LYS   A CD  1 
ATOM   2488 C CE  . LYS   A 1 365 ? -19.877 -17.447 9.873   1.00 65.46  ? 738 LYS   A CE  1 
ATOM   2489 N NZ  . LYS   A 1 365 ? -20.807 -16.637 10.642  1.00 67.95  ? 738 LYS   A NZ  1 
ATOM   2490 N N   . LEU   A 1 366 ? -20.299 -21.387 5.540   1.00 47.10  ? 739 LEU   A N   1 
ATOM   2491 C CA  . LEU   A 1 366 ? -20.330 -22.761 5.094   1.00 48.90  ? 739 LEU   A CA  1 
ATOM   2492 C C   . LEU   A 1 366 ? -20.369 -23.656 6.334   1.00 52.18  ? 739 LEU   A C   1 
ATOM   2493 O O   . LEU   A 1 366 ? -19.443 -23.629 7.149   1.00 54.60  ? 739 LEU   A O   1 
ATOM   2494 C CB  . LEU   A 1 366 ? -19.108 -22.996 4.205   1.00 50.20  ? 739 LEU   A CB  1 
ATOM   2495 C CG  . LEU   A 1 366 ? -19.059 -24.319 3.432   1.00 51.82  ? 739 LEU   A CG  1 
ATOM   2496 C CD1 . LEU   A 1 366 ? -18.288 -24.076 2.151   1.00 51.56  ? 739 LEU   A CD1 1 
ATOM   2497 C CD2 . LEU   A 1 366 ? -18.409 -25.486 4.248   1.00 54.39  ? 739 LEU   A CD2 1 
ATOM   2498 N N   . THR   A 1 367 ? -21.513 -24.338 6.522   1.00 50.19  ? 740 THR   A N   1 
ATOM   2499 C CA  . THR   A 1 367 ? -21.728 -25.229 7.652   1.00 52.35  ? 740 THR   A CA  1 
ATOM   2500 C C   . THR   A 1 367 ? -21.646 -26.679 7.163   1.00 53.68  ? 740 THR   A C   1 
ATOM   2501 O O   . THR   A 1 367 ? -22.360 -27.067 6.235   1.00 49.84  ? 740 THR   A O   1 
ATOM   2502 C CB  . THR   A 1 367 ? -23.087 -24.959 8.297   1.00 51.15  ? 740 THR   A CB  1 
ATOM   2503 O OG1 . THR   A 1 367 ? -23.235 -23.566 8.537   1.00 51.55  ? 740 THR   A OG1 1 
ATOM   2504 C CG2 . THR   A 1 367 ? -23.240 -25.695 9.611   1.00 55.20  ? 740 THR   A CG2 1 
ATOM   2505 N N   . THR   A 1 368 ? -20.796 -27.473 7.828   1.00 55.61  ? 741 THR   A N   1 
ATOM   2506 C CA  . THR   A 1 368 ? -20.575 -28.860 7.462   1.00 55.46  ? 741 THR   A CA  1 
ATOM   2507 C C   . THR   A 1 368 ? -21.374 -29.777 8.395   1.00 54.76  ? 741 THR   A C   1 
ATOM   2508 O O   . THR   A 1 368 ? -21.158 -29.757 9.605   1.00 53.02  ? 741 THR   A O   1 
ATOM   2509 C CB  . THR   A 1 368 ? -19.080 -29.167 7.511   1.00 57.18  ? 741 THR   A CB  1 
ATOM   2510 O OG1 . THR   A 1 368 ? -18.498 -28.317 6.529   1.00 55.26  ? 741 THR   A OG1 1 
ATOM   2511 C CG2 . THR   A 1 368 ? -18.786 -30.619 7.175   1.00 58.43  ? 741 THR   A CG2 1 
ATOM   2512 N N   . LEU   A 1 369 ? -22.267 -30.590 7.782   1.00 55.63  ? 742 LEU   A N   1 
ATOM   2513 C CA  . LEU   A 1 369 ? -23.203 -31.478 8.474   1.00 62.05  ? 742 LEU   A CA  1 
ATOM   2514 C C   . LEU   A 1 369 ? -22.891 -32.939 8.154   1.00 67.17  ? 742 LEU   A C   1 
ATOM   2515 O O   . LEU   A 1 369 ? -22.601 -33.287 7.006   1.00 67.09  ? 742 LEU   A O   1 
ATOM   2516 C CB  . LEU   A 1 369 ? -24.651 -31.206 8.068   1.00 59.23  ? 742 LEU   A CB  1 
ATOM   2517 C CG  . LEU   A 1 369 ? -25.234 -29.832 8.408   1.00 55.64  ? 742 LEU   A CG  1 
ATOM   2518 C CD1 . LEU   A 1 369 ? -26.722 -29.856 8.093   1.00 54.38  ? 742 LEU   A CD1 1 
ATOM   2519 C CD2 . LEU   A 1 369 ? -24.996 -29.424 9.848   1.00 57.25  ? 742 LEU   A CD2 1 
ATOM   2520 N N   . LEU   A 1 370 ? -23.055 -33.797 9.171   1.00 74.06  ? 743 LEU   A N   1 
ATOM   2521 C CA  . LEU   A 1 370 ? -23.124 -35.233 8.960   1.00 77.57  ? 743 LEU   A CA  1 
ATOM   2522 C C   . LEU   A 1 370 ? -24.476 -35.721 9.501   1.00 74.68  ? 743 LEU   A C   1 
ATOM   2523 O O   . LEU   A 1 370 ? -24.995 -35.177 10.540  1.00 78.01  ? 743 LEU   A O   1 
ATOM   2524 C CB  . LEU   A 1 370 ? -21.901 -35.853 9.651   1.00 90.50  ? 743 LEU   A CB  1 
ATOM   2525 C CG  . LEU   A 1 370 ? -21.432 -37.226 9.144   1.00 100.76 ? 743 LEU   A CG  1 
ATOM   2526 C CD1 . LEU   A 1 370 ? -19.956 -37.207 8.746   1.00 105.38 ? 743 LEU   A CD1 1 
ATOM   2527 C CD2 . LEU   A 1 370 ? -21.662 -38.296 10.205  1.00 106.19 ? 743 LEU   A CD2 1 
ATOM   2528 N N   . ALA   A 1 371 ? -25.064 -36.695 8.764   1.00 82.96  ? 744 ALA   A N   1 
ATOM   2529 C CA  . ALA   A 1 371 ? -26.313 -37.365 9.136   1.00 91.47  ? 744 ALA   A CA  1 
ATOM   2530 C C   . ALA   A 1 371 ? -26.075 -38.488 10.165  1.00 93.95  ? 744 ALA   A C   1 
ATOM   2531 O O   . ALA   A 1 371 ? -25.062 -38.496 10.867  1.00 89.96  ? 744 ALA   A O   1 
ATOM   2532 C CB  . ALA   A 1 371 ? -26.977 -37.895 7.879   1.00 90.81  ? 744 ALA   A CB  1 
ATOM   2533 N N   . HIS   A 1 372 ? -27.059 -39.399 10.300  1.00 103.86 ? 745 HIS   A N   1 
ATOM   2534 C CA  . HIS   A 1 372 ? -26.947 -40.548 11.196  1.00 108.84 ? 745 HIS   A CA  1 
ATOM   2535 C C   . HIS   A 1 372 ? -27.965 -41.620 10.785  1.00 105.56 ? 745 HIS   A C   1 
ATOM   2536 O O   . HIS   A 1 372 ? -28.152 -42.547 11.622  1.00 112.89 ? 745 HIS   A O   1 
ATOM   2537 C CB  . HIS   A 1 372 ? -27.107 -40.117 12.665  1.00 110.58 ? 745 HIS   A CB  1 
HETATM 2538 C C5  . A1BLV B 2 .   ? -18.932 -25.880 -25.436 1.00 67.88  ? 801 A1BLV A C5  1 
HETATM 2539 C C7  . A1BLV B 2 .   ? -19.875 -27.339 -23.623 1.00 56.75  ? 801 A1BLV A C7  1 
HETATM 2540 C C8  . A1BLV B 2 .   ? -20.005 -28.872 -23.709 1.00 55.83  ? 801 A1BLV A C8  1 
HETATM 2541 C C10 . A1BLV B 2 .   ? -21.247 -28.065 -21.833 1.00 52.37  ? 801 A1BLV A C10 1 
HETATM 2542 C C13 . A1BLV B 2 .   ? -22.298 -25.554 -21.216 1.00 46.90  ? 801 A1BLV A C13 1 
HETATM 2543 C C15 . A1BLV B 2 .   ? -22.136 -27.917 -20.756 1.00 48.10  ? 801 A1BLV A C15 1 
HETATM 2544 C C20 . A1BLV B 2 .   ? -18.171 -23.179 -27.976 1.00 85.40  ? 801 A1BLV A C20 1 
HETATM 2545 C C21 . A1BLV B 2 .   ? -17.090 -22.319 -28.198 1.00 96.97  ? 801 A1BLV A C21 1 
HETATM 2546 C C22 . A1BLV B 2 .   ? -17.146 -21.331 -29.191 1.00 103.69 ? 801 A1BLV A C22 1 
HETATM 2547 C C24 . A1BLV B 2 .   ? -14.783 -20.551 -28.671 1.00 119.51 ? 801 A1BLV A C24 1 
HETATM 2548 C C26 . A1BLV B 2 .   ? -14.386 -19.371 -30.739 1.00 126.32 ? 801 A1BLV A C26 1 
HETATM 2549 C C28 . A1BLV B 2 .   ? -18.311 -21.205 -29.961 1.00 95.02  ? 801 A1BLV A C28 1 
HETATM 2550 C C1  . A1BLV B 2 .   ? -15.271 -26.210 -23.660 1.00 72.49  ? 801 A1BLV A C1  1 
HETATM 2551 N N2  . A1BLV B 2 .   ? -15.589 -25.232 -24.671 1.00 72.32  ? 801 A1BLV A N2  1 
HETATM 2552 C C3  . A1BLV B 2 .   ? -16.795 -25.117 -25.240 1.00 71.86  ? 801 A1BLV A C3  1 
HETATM 2553 N N4  . A1BLV B 2 .   ? -17.757 -25.937 -24.792 1.00 68.83  ? 801 A1BLV A N4  1 
HETATM 2554 N N6  . A1BLV B 2 .   ? -19.950 -26.619 -24.886 1.00 60.95  ? 801 A1BLV A N6  1 
HETATM 2555 C C9  . A1BLV B 2 .   ? -20.612 -29.323 -22.365 1.00 54.01  ? 801 A1BLV A C9  1 
HETATM 2556 C C11 . A1BLV B 2 .   ? -20.892 -26.947 -22.578 1.00 52.76  ? 801 A1BLV A C11 1 
HETATM 2557 C C12 . A1BLV B 2 .   ? -21.420 -25.696 -22.274 1.00 51.95  ? 801 A1BLV A C12 1 
HETATM 2558 C C14 . A1BLV B 2 .   ? -22.659 -26.658 -20.459 1.00 46.36  ? 801 A1BLV A C14 1 
HETATM 2559 C C16 . A1BLV B 2 .   ? -22.392 -29.029 -19.877 1.00 53.58  ? 801 A1BLV A C16 1 
HETATM 2560 N N17 . A1BLV B 2 .   ? -22.576 -29.939 -19.206 1.00 54.21  ? 801 A1BLV A N17 1 
HETATM 2561 C C18 . A1BLV B 2 .   ? -19.142 -25.028 -26.530 1.00 73.40  ? 801 A1BLV A C18 1 
HETATM 2562 C C19 . A1BLV B 2 .   ? -18.072 -24.211 -26.906 1.00 76.37  ? 801 A1BLV A C19 1 
HETATM 2563 N N23 . A1BLV B 2 .   ? -16.015 -20.527 -29.466 1.00 116.12 ? 801 A1BLV A N23 1 
HETATM 2564 C C25 . A1BLV B 2 .   ? -13.701 -20.285 -29.698 1.00 123.56 ? 801 A1BLV A C25 1 
HETATM 2565 C C27 . A1BLV B 2 .   ? -15.899 -19.649 -30.634 1.00 118.75 ? 801 A1BLV A C27 1 
HETATM 2566 C C29 . A1BLV B 2 .   ? -19.380 -22.056 -29.742 1.00 90.19  ? 801 A1BLV A C29 1 
HETATM 2567 C C30 . A1BLV B 2 .   ? -19.315 -23.033 -28.760 1.00 88.28  ? 801 A1BLV A C30 1 
HETATM 2568 N N31 . A1BLV B 2 .   ? -16.895 -24.255 -26.265 1.00 77.25  ? 801 A1BLV A N31 1 
HETATM 2569 X UNK . UNX   C 3 .   ? -35.413 -32.853 -3.253  1.00 48.90  ? 802 UNX   A UNK 1 
HETATM 2570 O O   . HOH   D 4 .   ? -35.769 -35.181 -8.544  1.00 57.80  ? 901 HOH   A O   1 
HETATM 2571 O O   . HOH   D 4 .   ? -40.912 -17.855 -24.593 1.00 39.84  ? 902 HOH   A O   1 
HETATM 2572 O O   . HOH   D 4 .   ? -42.451 -12.486 3.188   1.00 57.41  ? 903 HOH   A O   1 
HETATM 2573 O O   . HOH   D 4 .   ? -28.774 -21.682 -11.294 1.00 29.65  ? 904 HOH   A O   1 
HETATM 2574 O O   . HOH   D 4 .   ? -29.829 -19.887 11.794  1.00 49.29  ? 905 HOH   A O   1 
HETATM 2575 O O   . HOH   D 4 .   ? -17.798 -25.952 7.649   1.00 45.86  ? 906 HOH   A O   1 
HETATM 2576 O O   . HOH   D 4 .   ? -40.108 -37.521 -13.112 1.00 46.10  ? 907 HOH   A O   1 
HETATM 2577 O O   . HOH   D 4 .   ? -50.255 -29.551 -9.085  1.00 61.37  ? 908 HOH   A O   1 
HETATM 2578 O O   . HOH   D 4 .   ? -24.132 -22.307 6.476   1.00 38.24  ? 909 HOH   A O   1 
HETATM 2579 O O   . HOH   D 4 .   ? -53.973 -32.275 -13.813 1.00 49.03  ? 910 HOH   A O   1 
HETATM 2580 O O   . HOH   D 4 .   ? -36.981 -17.988 8.376   1.00 40.91  ? 911 HOH   A O   1 
HETATM 2581 O O   . HOH   D 4 .   ? -36.109 -19.286 2.694   1.00 36.46  ? 912 HOH   A O   1 
HETATM 2582 O O   . HOH   D 4 .   ? -18.017 -13.261 0.963   1.00 42.00  ? 913 HOH   A O   1 
HETATM 2583 O O   . HOH   D 4 .   ? -13.597 -27.911 -1.602  1.00 47.36  ? 914 HOH   A O   1 
HETATM 2584 O O   . HOH   D 4 .   ? -23.274 -12.106 8.843   1.00 47.44  ? 915 HOH   A O   1 
HETATM 2585 O O   . HOH   D 4 .   ? -37.868 -20.427 7.680   1.00 39.03  ? 916 HOH   A O   1 
HETATM 2586 O O   . HOH   D 4 .   ? -30.520 -32.174 -23.162 1.00 51.43  ? 917 HOH   A O   1 
HETATM 2587 O O   . HOH   D 4 .   ? -9.023  -25.853 -0.154  1.00 59.17  ? 918 HOH   A O   1 
HETATM 2588 O O   . HOH   D 4 .   ? -29.972 -29.646 -13.656 1.00 50.51  ? 919 HOH   A O   1 
HETATM 2589 O O   . HOH   D 4 .   ? -33.408 -32.329 -21.109 1.00 42.91  ? 920 HOH   A O   1 
HETATM 2590 O O   . HOH   D 4 .   ? -40.794 -11.338 -0.936  1.00 50.13  ? 921 HOH   A O   1 
HETATM 2591 O O   . HOH   D 4 .   ? -26.109 -27.430 -12.387 1.00 55.86  ? 922 HOH   A O   1 
HETATM 2592 O O   . HOH   D 4 .   ? -36.123 -38.271 -13.437 1.00 37.35  ? 923 HOH   A O   1 
HETATM 2593 O O   . HOH   D 4 .   ? -39.604 -11.174 -11.799 1.00 47.23  ? 924 HOH   A O   1 
HETATM 2594 O O   . HOH   D 4 .   ? -13.577 -19.555 8.685   1.00 59.45  ? 925 HOH   A O   1 
HETATM 2595 O O   . HOH   D 4 .   ? -45.560 -15.699 5.768   1.00 61.75  ? 926 HOH   A O   1 
HETATM 2596 O O   . HOH   D 4 .   ? -35.489 -16.168 -6.163  1.00 45.61  ? 927 HOH   A O   1 
HETATM 2597 O O   . HOH   D 4 .   ? -34.248 -23.969 -34.328 1.00 38.71  ? 928 HOH   A O   1 
HETATM 2598 O O   . HOH   D 4 .   ? -33.508 -13.521 5.985   1.00 40.88  ? 929 HOH   A O   1 
HETATM 2599 O O   . HOH   D 4 .   ? -30.507 -13.169 -4.047  1.00 47.82  ? 930 HOH   A O   1 
HETATM 2600 O O   . HOH   D 4 .   ? -32.043 -23.191 -12.414 1.00 27.02  ? 931 HOH   A O   1 
HETATM 2601 O O   . HOH   D 4 .   ? -43.448 -36.260 -3.063  1.00 38.10  ? 932 HOH   A O   1 
HETATM 2602 O O   . HOH   D 4 .   ? -32.461 -13.806 -2.940  1.00 47.91  ? 933 HOH   A O   1 
HETATM 2603 O O   . HOH   D 4 .   ? -43.059 -8.288  -2.262  1.00 56.90  ? 934 HOH   A O   1 
HETATM 2604 O O   . HOH   D 4 .   ? -48.477 -37.955 -14.103 1.00 54.97  ? 935 HOH   A O   1 
HETATM 2605 O O   . HOH   D 4 .   ? -27.848 -19.259 -4.236  1.00 33.56  ? 936 HOH   A O   1 
HETATM 2606 O O   . HOH   D 4 .   ? -29.259 -18.984 -6.439  1.00 37.88  ? 937 HOH   A O   1 
HETATM 2607 O O   . HOH   D 4 .   ? -17.328 -7.720  -3.370  1.00 51.93  ? 938 HOH   A O   1 
HETATM 2608 O O   . HOH   D 4 .   ? -42.341 -16.420 4.129   1.00 51.63  ? 939 HOH   A O   1 
HETATM 2609 O O   . HOH   D 4 .   ? -44.941 -24.267 9.629   1.00 65.78  ? 940 HOH   A O   1 
HETATM 2610 O O   . HOH   D 4 .   ? -33.582 -30.159 -22.152 1.00 39.92  ? 941 HOH   A O   1 
HETATM 2611 O O   . HOH   D 4 .   ? -11.809 -24.449 -9.516  1.00 56.86  ? 942 HOH   A O   1 
HETATM 2612 O O   . HOH   D 4 .   ? -48.891 -22.252 7.959   1.00 55.99  ? 943 HOH   A O   1 
HETATM 2613 O O   . HOH   D 4 .   ? -42.985 -11.200 0.434   1.00 58.15  ? 944 HOH   A O   1 
HETATM 2614 O O   . HOH   D 4 .   ? -42.505 -15.767 -24.164 1.00 48.98  ? 945 HOH   A O   1 
HETATM 2615 O O   . HOH   D 4 .   ? -27.917 -31.885 -1.102  1.00 55.14  ? 946 HOH   A O   1 
HETATM 2616 O O   . HOH   D 4 .   ? -48.774 -15.044 -18.294 1.00 46.10  ? 947 HOH   A O   1 
HETATM 2617 O O   . HOH   D 4 .   ? -39.012 -15.126 -18.787 1.00 34.50  ? 948 HOH   A O   1 
HETATM 2618 O O   . HOH   D 4 .   ? -48.227 -11.497 -2.217  1.00 61.93  ? 949 HOH   A O   1 
HETATM 2619 O O   . HOH   D 4 .   ? -54.743 -25.703 -13.094 1.00 60.44  ? 950 HOH   A O   1 
HETATM 2620 O O   . HOH   D 4 .   ? -25.626 -24.398 -10.375 1.00 37.37  ? 951 HOH   A O   1 
HETATM 2621 O O   . HOH   D 4 .   ? -19.962 -28.115 -12.071 1.00 46.33  ? 952 HOH   A O   1 
HETATM 2622 O O   . HOH   D 4 .   ? -11.727 -29.878 -2.259  1.00 47.19  ? 953 HOH   A O   1 
HETATM 2623 O O   . HOH   D 4 .   ? -51.326 -15.489 -15.496 1.00 53.66  ? 954 HOH   A O   1 
HETATM 2624 O O   . HOH   D 4 .   ? -34.586 -20.058 -7.381  1.00 42.71  ? 955 HOH   A O   1 
HETATM 2625 O O   . HOH   D 4 .   ? -24.049 -7.154  -11.641 1.00 62.72  ? 956 HOH   A O   1 
HETATM 2626 O O   . HOH   D 4 .   ? -34.177 -17.838 -8.910  1.00 47.68  ? 957 HOH   A O   1 
HETATM 2627 O O   . HOH   D 4 .   ? -24.699 -26.997 -9.286  1.00 45.27  ? 958 HOH   A O   1 
HETATM 2628 O O   . HOH   D 4 .   ? -43.949 -20.448 -14.831 1.00 36.99  ? 959 HOH   A O   1 
HETATM 2629 O O   . HOH   D 4 .   ? -52.468 -27.889 -16.296 1.00 46.07  ? 960 HOH   A O   1 
HETATM 2630 O O   . HOH   D 4 .   ? -35.486 -7.861  6.577   1.00 54.14  ? 961 HOH   A O   1 
HETATM 2631 O O   . HOH   D 4 .   ? -8.668  -14.784 -10.746 1.00 72.31  ? 962 HOH   A O   1 
HETATM 2632 O O   . HOH   D 4 .   ? -38.437 -34.732 -1.260  1.00 49.47  ? 963 HOH   A O   1 
HETATM 2633 O O   . HOH   D 4 .   ? -24.498 -4.565  -0.279  1.00 47.79  ? 964 HOH   A O   1 
HETATM 2634 O O   . HOH   D 4 .   ? -31.600 -32.535 -11.897 1.00 59.93  ? 965 HOH   A O   1 
HETATM 2635 O O   . HOH   D 4 .   ? -30.168 -28.748 -2.575  1.00 49.08  ? 966 HOH   A O   1 
HETATM 2636 O O   . HOH   D 4 .   ? -30.783 -25.587 16.374  1.00 51.37  ? 967 HOH   A O   1 
HETATM 2637 O O   . HOH   D 4 .   ? -30.300 -19.680 -12.286 1.00 33.06  ? 968 HOH   A O   1 
HETATM 2638 O O   . HOH   D 4 .   ? -39.332 -37.349 -2.088  1.00 49.47  ? 969 HOH   A O   1 
HETATM 2639 O O   . HOH   D 4 .   ? -35.701 -22.616 -8.060  1.00 35.50  ? 970 HOH   A O   1 
HETATM 2640 O O   . HOH   D 4 .   ? -54.733 -22.944 -11.895 1.00 47.52  ? 971 HOH   A O   1 
HETATM 2641 O O   . HOH   D 4 .   ? -31.894 -28.073 -12.517 1.00 36.79  ? 972 HOH   A O   1 
HETATM 2642 O O   . HOH   D 4 .   ? -33.071 -24.642 -9.174  1.00 45.82  ? 973 HOH   A O   1 
HETATM 2643 O O   . HOH   D 4 .   ? -36.568 -14.701 -8.221  1.00 42.67  ? 974 HOH   A O   1 
HETATM 2644 O O   . HOH   D 4 .   ? -44.637 -13.129 4.331   1.00 61.94  ? 975 HOH   A O   1 
HETATM 2645 O O   . HOH   D 4 .   ? -35.052 -40.194 -12.724 1.00 57.18  ? 976 HOH   A O   1 
# 
loop_
_atom_site_anisotrop.id 
_atom_site_anisotrop.type_symbol 
_atom_site_anisotrop.pdbx_label_atom_id 
_atom_site_anisotrop.pdbx_label_alt_id 
_atom_site_anisotrop.pdbx_label_comp_id 
_atom_site_anisotrop.pdbx_label_asym_id 
_atom_site_anisotrop.pdbx_label_seq_id 
_atom_site_anisotrop.pdbx_PDB_ins_code 
_atom_site_anisotrop.U[1][1] 
_atom_site_anisotrop.U[2][2] 
_atom_site_anisotrop.U[3][3] 
_atom_site_anisotrop.U[1][2] 
_atom_site_anisotrop.U[1][3] 
_atom_site_anisotrop.U[2][3] 
_atom_site_anisotrop.pdbx_auth_seq_id 
_atom_site_anisotrop.pdbx_auth_comp_id 
_atom_site_anisotrop.pdbx_auth_asym_id 
_atom_site_anisotrop.pdbx_auth_atom_id 
1    N N   . GLN   A 21  ? 1.6621 1.1933 0.8009 -0.1061 -0.1211 0.3392  394 GLN   A N   
2    C CA  . GLN   A 21  ? 1.6229 1.1445 0.8104 -0.0775 -0.1430 0.3248  394 GLN   A CA  
3    C C   . GLN   A 21  ? 1.6505 1.1267 0.8780 -0.0736 -0.1422 0.3329  394 GLN   A C   
4    O O   . GLN   A 21  ? 1.7535 1.1843 0.9737 -0.0653 -0.1610 0.3599  394 GLN   A O   
5    C CB  . GLN   A 21  ? 1.6422 1.1594 0.8038 -0.0599 -0.1752 0.3401  394 GLN   A CB  
6    N N   . PRO   A 22  ? 1.6074 1.0947 0.8790 -0.0777 -0.1218 0.3082  395 PRO   A N   
7    C CA  . PRO   A 22  ? 1.5894 1.0424 0.9066 -0.0689 -0.1231 0.3063  395 PRO   A CA  
8    C C   . PRO   A 22  ? 1.5023 0.9577 0.8640 -0.0390 -0.1436 0.2907  395 PRO   A C   
9    O O   . PRO   A 22  ? 1.5174 0.9440 0.9155 -0.0271 -0.1487 0.2897  395 PRO   A O   
10   C CB  . PRO   A 22  ? 1.4600 0.9347 0.8048 -0.0843 -0.0942 0.2830  395 PRO   A CB  
11   C CG  . PRO   A 22  ? 1.4777 1.0028 0.7986 -0.0960 -0.0792 0.2682  395 PRO   A CG  
12   C CD  . PRO   A 22  ? 1.5344 1.0694 0.8145 -0.0886 -0.0980 0.2792  395 PRO   A CD  
13   N N   . PHE   A 23  ? 1.3337 0.8271 0.6957 -0.0278 -0.1539 0.2753  396 PHE   A N   
14   C CA  . PHE   A 23  ? 1.2701 0.7726 0.6724 -0.0025 -0.1734 0.2620  396 PHE   A CA  
15   C C   . PHE   A 23  ? 1.2856 0.8051 0.6628 0.0084  -0.1977 0.2680  396 PHE   A C   
16   O O   . PHE   A 23  ? 1.3693 0.9093 0.7051 -0.0035 -0.1947 0.2695  396 PHE   A O   
17   C CB  . PHE   A 23  ? 1.2009 0.7410 0.6477 0.0004  -0.1608 0.2278  396 PHE   A CB  
18   C CG  . PHE   A 23  ? 1.1502 0.6802 0.6272 -0.0072 -0.1393 0.2183  396 PHE   A CG  
19   C CD1 . PHE   A 23  ? 1.1406 0.6481 0.6547 0.0060  -0.1443 0.2177  396 PHE   A CD1 
20   C CD2 . PHE   A 23  ? 1.1062 0.6514 0.5736 -0.0271 -0.1146 0.2091  396 PHE   A CD2 
21   C CE1 . PHE   A 23  ? 1.1419 0.6405 0.6799 -0.0016 -0.1257 0.2085  396 PHE   A CE1 
22   C CE2 . PHE   A 23  ? 1.1360 0.6741 0.6300 -0.0343 -0.0968 0.2007  396 PHE   A CE2 
23   C CZ  . PHE   A 23  ? 1.1701 0.6847 0.6985 -0.0220 -0.1027 0.2001  396 PHE   A CZ  
24   N N   . ILE   A 24  ? 1.3015 0.8166 0.7067 0.0318  -0.2216 0.2688  397 ILE   A N   
25   C CA  . ILE   A 24  ? 1.3404 0.8802 0.7355 0.0450  -0.2469 0.2680  397 ILE   A CA  
26   C C   . ILE   A 24  ? 1.2376 0.8157 0.6866 0.0563  -0.2493 0.2366  397 ILE   A C   
27   O O   . ILE   A 24  ? 1.2150 0.7885 0.7118 0.0670  -0.2466 0.2276  397 ILE   A O   
28   C CB  . ILE   A 24  ? 1.4367 0.9446 0.8192 0.0633  -0.2758 0.2967  397 ILE   A CB  
29   C CG1 . ILE   A 24  ? 1.5386 1.0063 0.8606 0.0489  -0.2748 0.3324  397 ILE   A CG1 
30   C CG2 . ILE   A 24  ? 1.4553 0.9966 0.8396 0.0801  -0.3044 0.2912  397 ILE   A CG2 
31   C CD1 . ILE   A 24  ? 1.6096 1.0207 0.9351 0.0620  -0.2894 0.3601  397 ILE   A CD1 
32   N N   . VAL   A 25  ? 1.2088 0.8246 0.6481 0.0524  -0.2541 0.2200  398 VAL   A N   
33   C CA  . VAL   A 25  ? 1.1900 0.8419 0.6759 0.0591  -0.2577 0.1917  398 VAL   A CA  
34   C C   . VAL   A 25  ? 1.1628 0.8277 0.6692 0.0796  -0.2886 0.1951  398 VAL   A C   
35   O O   . VAL   A 25  ? 1.1866 0.8667 0.6638 0.0817  -0.3085 0.1989  398 VAL   A O   
36   C CB  . VAL   A 25  ? 1.2386 0.9207 0.7038 0.0449  -0.2502 0.1711  398 VAL   A CB  
37   C CG1 . VAL   A 25  ? 1.1948 0.9095 0.7074 0.0483  -0.2537 0.1425  398 VAL   A CG1 
38   C CG2 . VAL   A 25  ? 1.2616 0.9351 0.7041 0.0265  -0.2208 0.1685  398 VAL   A CG2 
39   N N   . LEU   A 26  ? 1.1163 0.7812 0.6746 0.0948  -0.2923 0.1909  399 LEU   A N   
40   C CA  . LEU   A 26  ? 1.1011 0.7846 0.6870 0.1160  -0.3208 0.1919  399 LEU   A CA  
41   C C   . LEU   A 26  ? 1.0371 0.7699 0.6511 0.1131  -0.3287 0.1663  399 LEU   A C   
42   O O   . LEU   A 26  ? 1.0481 0.8049 0.6703 0.1251  -0.3553 0.1662  399 LEU   A O   
43   C CB  . LEU   A 26  ? 1.0887 0.7593 0.7212 0.1343  -0.3211 0.1940  399 LEU   A CB  
44   C CG  . LEU   A 26  ? 1.1361 0.7530 0.7470 0.1408  -0.3196 0.2190  399 LEU   A CG  
45   C CD1 . LEU   A 26  ? 1.1199 0.7301 0.7838 0.1601  -0.3186 0.2125  399 LEU   A CD1 
46   C CD2 . LEU   A 26  ? 1.1832 0.7778 0.7498 0.1503  -0.3459 0.2470  399 LEU   A CD2 
47   N N   . GLY   A 27  ? 0.9892 0.7365 0.6185 0.0968  -0.3072 0.1448  400 GLY   A N   
48   C CA  . GLY   A 27  ? 0.9734 0.7607 0.6277 0.0907  -0.3143 0.1210  400 GLY   A CA  
49   C C   . GLY   A 27  ? 0.9385 0.7315 0.6132 0.0744  -0.2888 0.1006  400 GLY   A C   
50   O O   . GLY   A 27  ? 0.8911 0.6646 0.5737 0.0711  -0.2663 0.1032  400 GLY   A O   
51   N N   . GLN   A 28  ? 0.9407 0.7597 0.6230 0.0645  -0.2946 0.0802  401 GLN   A N   
52   C CA  . GLN   A 28  ? 0.9232 0.7487 0.6302 0.0509  -0.2762 0.0604  401 GLN   A CA  
53   C C   . GLN   A 28  ? 0.8681 0.7273 0.6226 0.0486  -0.2896 0.0442  401 GLN   A C   
54   O O   . GLN   A 28  ? 0.8512 0.7298 0.5988 0.0466  -0.3104 0.0352  401 GLN   A O   
55   C CB  . GLN   A 28  ? 0.9589 0.7763 0.6247 0.0377  -0.2672 0.0491  401 GLN   A CB  
56   C CG  . GLN   A 28  ? 0.9472 0.7617 0.6355 0.0265  -0.2459 0.0323  401 GLN   A CG  
57   C CD  . GLN   A 28  ? 0.9524 0.7553 0.6013 0.0177  -0.2316 0.0231  401 GLN   A CD  
58   O OE1 . GLN   A 28  ? 1.0153 0.8278 0.6448 0.0123  -0.2402 0.0062  401 GLN   A OE1 
59   N NE2 . GLN   A 28  ? 0.9384 0.7230 0.5772 0.0162  -0.2095 0.0319  401 GLN   A NE2 
60   N N   A GLU   A 29  ? 0.8061 0.6733 0.6075 0.0470  -0.2769 0.0404  402 GLU   A N   
61   N N   B GLU   A 29  ? 0.8287 0.6964 0.6308 0.0476  -0.2775 0.0408  402 GLU   A N   
62   C CA  A GLU   A 29  ? 0.7686 0.6685 0.6182 0.0406  -0.2853 0.0267  402 GLU   A CA  
63   C CA  B GLU   A 29  ? 0.8050 0.7050 0.6548 0.0406  -0.2853 0.0266  402 GLU   A CA  
64   C C   A GLU   A 29  ? 0.7505 0.6435 0.6171 0.0246  -0.2651 0.0148  402 GLU   A C   
65   C C   B GLU   A 29  ? 0.7727 0.6650 0.6368 0.0242  -0.2656 0.0143  402 GLU   A C   
66   O O   A GLU   A 29  ? 0.7408 0.6092 0.5923 0.0232  -0.2441 0.0190  402 GLU   A O   
67   O O   B GLU   A 29  ? 0.7653 0.6319 0.6107 0.0223  -0.2452 0.0177  402 GLU   A O   
68   C CB  A GLU   A 29  ? 0.7255 0.6487 0.6187 0.0540  -0.2906 0.0346  402 GLU   A CB  
69   C CB  B GLU   A 29  ? 0.7820 0.7065 0.6792 0.0522  -0.2888 0.0331  402 GLU   A CB  
70   C CG  A GLU   A 29  ? 0.7344 0.6558 0.6103 0.0744  -0.3095 0.0495  402 GLU   A CG  
71   C CG  B GLU   A 29  ? 0.8094 0.7441 0.7013 0.0718  -0.3119 0.0445  402 GLU   A CG  
72   C CD  A GLU   A 29  ? 0.7490 0.6963 0.6197 0.0773  -0.3396 0.0451  402 GLU   A CD  
73   C CD  B GLU   A 29  ? 0.8236 0.7251 0.6892 0.0875  -0.3053 0.0635  402 GLU   A CD  
74   O OE1 A GLU   A 29  ? 0.7253 0.6992 0.6178 0.0634  -0.3470 0.0280  402 GLU   A OE1 
75   O OE1 B GLU   A 29  ? 0.7726 0.6639 0.6577 0.0915  -0.2865 0.0670  402 GLU   A OE1 
76   O OE2 A GLU   A 29  ? 0.7644 0.7035 0.6075 0.0926  -0.3565 0.0593  402 GLU   A OE2 
77   O OE2 B GLU   A 29  ? 0.9127 0.7979 0.7366 0.0949  -0.3201 0.0752  402 GLU   A OE2 
78   N N   . GLU   A 30  ? 0.7530 0.6678 0.6517 0.0122  -0.2730 0.0007  403 GLU   A N   
79   C CA  . GLU   A 30  ? 0.7453 0.6501 0.6587 -0.0036 -0.2586 -0.0100 403 GLU   A CA  
80   C C   . GLU   A 30  ? 0.6714 0.6011 0.6390 -0.0101 -0.2534 -0.0080 403 GLU   A C   
81   O O   . GLU   A 30  ? 0.6749 0.6375 0.6734 -0.0121 -0.2692 -0.0112 403 GLU   A O   
82   C CB  . GLU   A 30  ? 0.7673 0.6708 0.6693 -0.0162 -0.2728 -0.0294 403 GLU   A CB  
83   C CG  . GLU   A 30  ? 0.7939 0.6785 0.7074 -0.0311 -0.2602 -0.0409 403 GLU   A CG  
84   C CD  . GLU   A 30  ? 0.8221 0.6969 0.7187 -0.0410 -0.2731 -0.0632 403 GLU   A CD  
85   O OE1 . GLU   A 30  ? 0.8287 0.7132 0.7564 -0.0555 -0.2848 -0.0752 403 GLU   A OE1 
86   O OE2 . GLU   A 30  ? 0.8780 0.7364 0.7300 -0.0348 -0.2713 -0.0694 403 GLU   A OE2 
87   N N   . TYR   A 31  ? 0.6514 0.5683 0.6298 -0.0147 -0.2315 -0.0034 404 TYR   A N   
88   C CA  . TYR   A 31  ? 0.6381 0.5768 0.6629 -0.0262 -0.2243 -0.0023 404 TYR   A CA  
89   C C   . TYR   A 31  ? 0.6643 0.5855 0.6931 -0.0455 -0.2223 -0.0122 404 TYR   A C   
90   O O   . TYR   A 31  ? 0.6519 0.5409 0.6562 -0.0458 -0.2101 -0.0134 404 TYR   A O   
91   C CB  . TYR   A 31  ? 0.5863 0.5250 0.6207 -0.0188 -0.2028 0.0098  404 TYR   A CB  
92   C CG  . TYR   A 31  ? 0.5686 0.5374 0.6488 -0.0297 -0.1944 0.0131  404 TYR   A CG  
93   C CD1 . TYR   A 31  ? 0.5919 0.6048 0.7093 -0.0272 -0.2031 0.0134  404 TYR   A CD1 
94   C CD2 . TYR   A 31  ? 0.5414 0.4976 0.6275 -0.0421 -0.1780 0.0167  404 TYR   A CD2 
95   C CE1 . TYR   A 31  ? 0.5698 0.6164 0.7288 -0.0387 -0.1931 0.0168  404 TYR   A CE1 
96   C CE2 . TYR   A 31  ? 0.5326 0.5178 0.6565 -0.0536 -0.1690 0.0225  404 TYR   A CE2 
97   C CZ  . TYR   A 31  ? 0.5463 0.5784 0.7068 -0.0529 -0.1753 0.0224  404 TYR   A CZ  
98   O OH  . TYR   A 31  ? 0.5141 0.5806 0.7118 -0.0660 -0.1641 0.0284  404 TYR   A OH  
99   N N   . GLY   A 32  ? 0.6795 0.6223 0.7413 -0.0614 -0.2351 -0.0195 405 GLY   A N   
100  C CA  . GLY   A 32  ? 0.7138 0.6356 0.7784 -0.0801 -0.2402 -0.0319 405 GLY   A CA  
101  C C   . GLY   A 32  ? 0.7065 0.6403 0.8149 -0.1006 -0.2339 -0.0263 405 GLY   A C   
102  O O   . GLY   A 32  ? 0.7775 0.6985 0.8979 -0.1191 -0.2428 -0.0360 405 GLY   A O   
103  N N   . GLU   A 33  ? 0.6998 0.6561 0.8303 -0.0982 -0.2180 -0.0106 406 GLU   A N   
104  C CA  . GLU   A 33  ? 0.6996 0.6763 0.8716 -0.1191 -0.2112 -0.0026 406 GLU   A CA  
105  C C   . GLU   A 33  ? 0.7258 0.6625 0.8898 -0.1308 -0.1985 0.0035  406 GLU   A C   
106  O O   . GLU   A 33  ? 0.7503 0.6917 0.9430 -0.1527 -0.1962 0.0101  406 GLU   A O   
107  C CB  . GLU   A 33  ? 0.7157 0.7356 0.9126 -0.1115 -0.1978 0.0102  406 GLU   A CB  
108  C CG  . GLU   A 33  ? 0.7741 0.8368 0.9864 -0.0980 -0.2113 0.0051  406 GLU   A CG  
109  C CD  . GLU   A 33  ? 0.8374 0.9300 1.0807 -0.1146 -0.2324 -0.0053 406 GLU   A CD  
110  O OE1 . GLU   A 33  ? 0.8561 0.9824 1.1410 -0.1342 -0.2281 -0.0012 406 GLU   A OE1 
111  O OE2 . GLU   A 33  ? 0.9087 0.9927 1.1339 -0.1094 -0.2529 -0.0177 406 GLU   A OE2 
112  N N   . HIS   A 34  ? 0.6996 0.5995 0.8265 -0.1162 -0.1897 0.0030  407 HIS   A N   
113  C CA  . HIS   A 34  ? 0.7013 0.5621 0.8191 -0.1230 -0.1808 0.0070  407 HIS   A CA  
114  C C   . HIS   A 34  ? 0.7740 0.5998 0.8836 -0.1323 -0.1969 -0.0102 407 HIS   A C   
115  O O   . HIS   A 34  ? 0.7890 0.6104 0.8782 -0.1240 -0.2099 -0.0272 407 HIS   A O   
116  C CB  . HIS   A 34  ? 0.6820 0.5229 0.7673 -0.1036 -0.1654 0.0116  407 HIS   A CB  
117  C CG  . HIS   A 34  ? 0.6783 0.5455 0.7697 -0.0952 -0.1483 0.0268  407 HIS   A CG  
118  N ND1 . HIS   A 34  ? 0.6560 0.5278 0.7615 -0.1034 -0.1340 0.0420  407 HIS   A ND1 
119  C CD2 . HIS   A 34  ? 0.6424 0.5297 0.7247 -0.0783 -0.1436 0.0281  407 HIS   A CD2 
120  C CE1 . HIS   A 34  ? 0.6279 0.5249 0.7329 -0.0917 -0.1207 0.0496  407 HIS   A CE1 
121  N NE2 . HIS   A 34  ? 0.6508 0.5554 0.7434 -0.0761 -0.1265 0.0409  407 HIS   A NE2 
122  N N   . HIS   A 35  ? 0.8041 0.6032 0.9282 -0.1491 -0.1961 -0.0056 408 HIS   A N   
123  C CA  . HIS   A 35  ? 0.8865 0.6480 1.0090 -0.1597 -0.2120 -0.0229 408 HIS   A CA  
124  C C   . HIS   A 35  ? 0.8763 0.5894 0.9762 -0.1499 -0.2052 -0.0245 408 HIS   A C   
125  O O   . HIS   A 35  ? 0.9593 0.6345 1.0557 -0.1546 -0.2172 -0.0405 408 HIS   A O   
126  C CB  . HIS   A 35  ? 0.9178 0.6872 1.0807 -0.1894 -0.2213 -0.0181 408 HIS   A CB  
127  C CG  . HIS   A 35  ? 0.9652 0.7884 1.1526 -0.1968 -0.2293 -0.0198 408 HIS   A CG  
128  N ND1 . HIS   A 35  ? 0.9854 0.8258 1.1592 -0.1854 -0.2439 -0.0385 408 HIS   A ND1 
129  C CD2 . HIS   A 35  ? 0.9683 0.8354 1.1932 -0.2132 -0.2249 -0.0054 408 HIS   A CD2 
130  C CE1 . HIS   A 35  ? 1.0151 0.9063 1.2189 -0.1932 -0.2498 -0.0355 408 HIS   A CE1 
131  N NE2 . HIS   A 35  ? 1.0231 0.9331 1.2598 -0.2102 -0.2377 -0.0166 408 HIS   A NE2 
132  N N   . SER   A 36  ? 0.8103 0.5264 0.8961 -0.1353 -0.1871 -0.0098 409 SER   A N   
133  C CA  . SER   A 36  ? 0.8305 0.5098 0.8959 -0.1225 -0.1797 -0.0106 409 SER   A CA  
134  C C   . SER   A 36  ? 0.8262 0.5187 0.8619 -0.0994 -0.1671 -0.0121 409 SER   A C   
135  O O   . SER   A 36  ? 0.7752 0.5020 0.8098 -0.0947 -0.1606 -0.0048 409 SER   A O   
136  C CB  . SER   A 36  ? 0.8244 0.4920 0.9059 -0.1321 -0.1703 0.0126  409 SER   A CB  
137  O OG  . SER   A 36  ? 0.9357 0.5839 1.0431 -0.1558 -0.1822 0.0156  409 SER   A OG  
138  N N   . SER   A 37  ? 0.8041 0.4689 0.8188 -0.0854 -0.1630 -0.0205 410 SER   A N   
139  C CA  . SER   A 37  ? 0.7812 0.4559 0.7684 -0.0661 -0.1509 -0.0232 410 SER   A CA  
140  C C   . SER   A 37  ? 0.7364 0.4395 0.7281 -0.0638 -0.1355 -0.0019 410 SER   A C   
141  O O   . SER   A 37  ? 0.7151 0.4205 0.7248 -0.0716 -0.1293 0.0155  410 SER   A O   
142  C CB  . SER   A 37  ? 0.7704 0.4167 0.7435 -0.0536 -0.1473 -0.0324 410 SER   A CB  
143  O OG  . SER   A 37  ? 0.7857 0.4467 0.7336 -0.0378 -0.1353 -0.0360 410 SER   A OG  
144  N N   . ILE   A 38  ? 0.6816 0.4041 0.6541 -0.0527 -0.1295 -0.0043 411 ILE   A N   
145  C CA  . ILE   A 38  ? 0.6319 0.3799 0.6070 -0.0487 -0.1166 0.0109  411 ILE   A CA  
146  C C   . ILE   A 38  ? 0.6075 0.3478 0.5718 -0.0395 -0.1025 0.0165  411 ILE   A C   
147  O O   . ILE   A 38  ? 0.6135 0.3392 0.5580 -0.0300 -0.1004 0.0056  411 ILE   A O   
148  C CB  . ILE   A 38  ? 0.6077 0.3731 0.5672 -0.0409 -0.1183 0.0068  411 ILE   A CB  
149  C CG1 . ILE   A 38  ? 0.6439 0.4221 0.6159 -0.0487 -0.1344 0.0016  411 ILE   A CG1 
150  C CG2 . ILE   A 38  ? 0.5697 0.3551 0.5308 -0.0344 -0.1052 0.0196  411 ILE   A CG2 
151  C CD1 . ILE   A 38  ? 0.6451 0.4421 0.6535 -0.0625 -0.1367 0.0119  411 ILE   A CD1 
152  N N   . MET   A 39  ? 0.6215 0.3769 0.5985 -0.0420 -0.0923 0.0325  412 MET   A N   
153  C CA  . MET   A 39  ? 0.6375 0.3910 0.6048 -0.0335 -0.0801 0.0378  412 MET   A CA  
154  C C   . MET   A 39  ? 0.5998 0.3731 0.5548 -0.0250 -0.0696 0.0384  412 MET   A C   
155  O O   . MET   A 39  ? 0.6266 0.3950 0.5640 -0.0162 -0.0630 0.0330  412 MET   A O   
156  C CB  . MET   A 39  ? 0.6362 0.3936 0.6206 -0.0414 -0.0756 0.0549  412 MET   A CB  
157  C CG  . MET   A 39  ? 0.7180 0.4731 0.6920 -0.0322 -0.0660 0.0600  412 MET   A CG  
158  S SD  . MET   A 39  ? 0.7671 0.5236 0.7551 -0.0414 -0.0631 0.0826  412 MET   A SD  
159  C CE  . MET   A 39  ? 0.6489 0.3755 0.6534 -0.0559 -0.0788 0.0837  412 MET   A CE  
160  N N   . HIS   A 40  ? 0.5959 0.3922 0.5631 -0.0279 -0.0679 0.0452  413 HIS   A N   
161  C CA  . HIS   A 40  ? 0.5893 0.4002 0.5481 -0.0197 -0.0600 0.0453  413 HIS   A CA  
162  C C   . HIS   A 40  ? 0.5912 0.4158 0.5589 -0.0197 -0.0682 0.0440  413 HIS   A C   
163  O O   . HIS   A 40  ? 0.6335 0.4701 0.6226 -0.0280 -0.0752 0.0468  413 HIS   A O   
164  C CB  . HIS   A 40  ? 0.6021 0.4321 0.5699 -0.0191 -0.0476 0.0545  413 HIS   A CB  
165  C CG  . HIS   A 40  ? 0.5943 0.4164 0.5551 -0.0181 -0.0408 0.0578  413 HIS   A CG  
166  N ND1 . HIS   A 40  ? 0.5508 0.3659 0.4935 -0.0102 -0.0347 0.0517  413 HIS   A ND1 
167  C CD2 . HIS   A 40  ? 0.6417 0.4630 0.6117 -0.0241 -0.0401 0.0677  413 HIS   A CD2 
168  C CE1 . HIS   A 40  ? 0.5768 0.3893 0.5193 -0.0095 -0.0314 0.0560  413 HIS   A CE1 
169  N NE2 . HIS   A 40  ? 0.5818 0.3957 0.5392 -0.0173 -0.0350 0.0668  413 HIS   A NE2 
170  N N   . CYS   A 41  ? 0.6066 0.4299 0.5589 -0.0106 -0.0680 0.0408  414 CYS   A N   
171  C CA  . CYS   A 41  ? 0.5488 0.3875 0.5112 -0.0061 -0.0748 0.0417  414 CYS   A CA  
172  C C   . CYS   A 41  ? 0.5405 0.3771 0.4912 0.0044  -0.0675 0.0428  414 CYS   A C   
173  O O   . CYS   A 41  ? 0.5344 0.3513 0.4597 0.0074  -0.0655 0.0409  414 CYS   A O   
174  C CB  . CYS   A 41  ? 0.5935 0.4252 0.5475 -0.0065 -0.0909 0.0364  414 CYS   A CB  
175  S SG  . CYS   A 41  ? 0.6673 0.4706 0.5807 -0.0035 -0.0923 0.0295  414 CYS   A SG  
176  N N   . ARG   A 42  ? 0.5324 0.3902 0.5029 0.0096  -0.0640 0.0450  415 ARG   A N   
177  C CA  . ARG   A 42  ? 0.5366 0.3897 0.4995 0.0197  -0.0569 0.0440  415 ARG   A CA  
178  C C   . ARG   A 42  ? 0.5127 0.3822 0.4943 0.0306  -0.0637 0.0430  415 ARG   A C   
179  O O   . ARG   A 42  ? 0.5024 0.4023 0.5119 0.0295  -0.0651 0.0427  415 ARG   A O   
180  C CB  . ARG   A 42  ? 0.5770 0.4409 0.5450 0.0175  -0.0417 0.0438  415 ARG   A CB  
181  C CG  . ARG   A 42  ? 0.5421 0.3913 0.4930 0.0105  -0.0351 0.0443  415 ARG   A CG  
182  C CD  . ARG   A 42  ? 0.5907 0.4137 0.5141 0.0127  -0.0346 0.0412  415 ARG   A CD  
183  N NE  . ARG   A 42  ? 0.6080 0.4246 0.5261 0.0196  -0.0311 0.0395  415 ARG   A NE  
184  C CZ  . ARG   A 42  ? 0.6387 0.4582 0.5560 0.0204  -0.0203 0.0358  415 ARG   A CZ  
185  N NH1 . ARG   A 42  ? 0.5567 0.3875 0.4758 0.0154  -0.0124 0.0351  415 ARG   A NH1 
186  N NH2 . ARG   A 42  ? 0.6174 0.4283 0.5331 0.0266  -0.0190 0.0326  415 ARG   A NH2 
187  N N   . VAL   A 43  ? 0.5146 0.3643 0.4816 0.0410  -0.0683 0.0431  416 VAL   A N   
188  C CA  . VAL   A 43  ? 0.5245 0.3847 0.5088 0.0555  -0.0754 0.0413  416 VAL   A CA  
189  C C   . VAL   A 43  ? 0.4835 0.3581 0.4827 0.0616  -0.0621 0.0347  416 VAL   A C   
190  O O   . VAL   A 43  ? 0.5262 0.3883 0.5112 0.0568  -0.0504 0.0331  416 VAL   A O   
191  C CB  . VAL   A 43  ? 0.5940 0.4205 0.5536 0.0640  -0.0863 0.0461  416 VAL   A CB  
192  C CG1 . VAL   A 43  ? 0.6135 0.4461 0.5912 0.0825  -0.0973 0.0449  416 VAL   A CG1 
193  C CG2 . VAL   A 43  ? 0.6099 0.4242 0.5476 0.0561  -0.0974 0.0513  416 VAL   A CG2 
194  N N   . ASP   A 44  ? 0.5392 0.4460 0.5688 0.0714  -0.0635 0.0294  417 ASP   A N   
195  C CA  . ASP   A 44  ? 0.5623 0.4886 0.6074 0.0793  -0.0513 0.0199  417 ASP   A CA  
196  C C   . ASP   A 44  ? 0.6162 0.5092 0.6486 0.0937  -0.0539 0.0149  417 ASP   A C   
197  O O   . ASP   A 44  ? 0.6434 0.5019 0.6570 0.0968  -0.0656 0.0217  417 ASP   A O   
198  C CB  . ASP   A 44  ? 0.5287 0.5030 0.6113 0.0871  -0.0524 0.0140  417 ASP   A CB  
199  C CG  . ASP   A 44  ? 0.5593 0.5330 0.6566 0.1075  -0.0677 0.0098  417 ASP   A CG  
200  O OD1 . ASP   A 44  ? 0.5465 0.4886 0.6260 0.1095  -0.0825 0.0177  417 ASP   A OD1 
201  O OD2 . ASP   A 44  ? 0.5536 0.5610 0.6803 0.1222  -0.0652 -0.0014 417 ASP   A OD2 
202  N N   . CYS   A 45  ? 0.6106 0.5150 0.6539 0.1025  -0.0439 0.0027  418 CYS   A N   
203  C CA  . CYS   A 45  ? 0.6757 0.5437 0.7066 0.1131  -0.0449 -0.0039 418 CYS   A CA  
204  C C   . CYS   A 45  ? 0.6707 0.5258 0.7142 0.1342  -0.0609 -0.0056 418 CYS   A C   
205  O O   . CYS   A 45  ? 0.7260 0.5366 0.7534 0.1408  -0.0675 -0.0041 418 CYS   A O   
206  C CB  . CYS   A 45  ? 0.7334 0.6173 0.7710 0.1156  -0.0299 -0.0196 418 CYS   A CB  
207  S SG  . CYS   A 45  ? 0.8460 0.7293 0.8602 0.0934  -0.0148 -0.0162 418 CYS   A SG  
208  N N   . SER   A 46  ? 0.6226 0.5162 0.6952 0.1438  -0.0679 -0.0076 419 SER   A N   
209  C CA  . SER   A 46  ? 0.6781 0.5637 0.7646 0.1655  -0.0861 -0.0079 419 SER   A CA  
210  C C   . SER   A 46  ? 0.7121 0.5617 0.7729 0.1608  -0.1030 0.0102  419 SER   A C   
211  O O   . SER   A 46  ? 0.8104 0.6369 0.8708 0.1780  -0.1201 0.0145  419 SER   A O   
212  C CB  . SER   A 46  ? 0.6634 0.6085 0.7920 0.1770  -0.0887 -0.0167 419 SER   A CB  
213  O OG  . SER   A 46  ? 0.6290 0.5982 0.7625 0.1633  -0.0952 -0.0058 419 SER   A OG  
214  N N   . GLY   A 47  ? 0.6552 0.5012 0.6943 0.1390  -0.0990 0.0206  420 GLY   A N   
215  C CA  . GLY   A 47  ? 0.6681 0.4861 0.6804 0.1334  -0.1134 0.0356  420 GLY   A CA  
216  C C   . GLY   A 47  ? 0.6450 0.4943 0.6763 0.1383  -0.1298 0.0383  420 GLY   A C   
217  O O   . GLY   A 47  ? 0.6533 0.4837 0.6635 0.1373  -0.1450 0.0493  420 GLY   A O   
218  N N   . ARG   A 48  ? 0.6242 0.5248 0.6941 0.1408  -0.1256 0.0282  421 ARG   A N   
219  C CA  . ARG   A 48  ? 0.6196 0.5587 0.7180 0.1474  -0.1410 0.0274  421 ARG   A CA  
220  C C   . ARG   A 48  ? 0.6027 0.5821 0.7176 0.1261  -0.1340 0.0260  421 ARG   A C   
221  O O   . ARG   A 48  ? 0.5992 0.6111 0.7368 0.1259  -0.1469 0.0254  421 ARG   A O   
222  C CB  . ARG   A 48  ? 0.6303 0.6004 0.7678 0.1723  -0.1449 0.0155  421 ARG   A CB  
223  C CG  . ARG   A 48  ? 0.6592 0.5897 0.7883 0.1978  -0.1574 0.0161  421 ARG   A CG  
224  C CD  . ARG   A 48  ? 0.6287 0.5945 0.8019 0.2261  -0.1635 0.0013  421 ARG   A CD  
225  N N   . ARG   A 49  ? 0.5551 0.5332 0.6609 0.1081  -0.1151 0.0258  422 ARG   A N   
226  C CA  . ARG   A 49  ? 0.5481 0.5563 0.6679 0.0873  -0.1101 0.0271  422 ARG   A CA  
227  C C   . ARG   A 49  ? 0.5345 0.5086 0.6206 0.0690  -0.1027 0.0336  422 ARG   A C   
228  O O   . ARG   A 49  ? 0.5662 0.5092 0.6271 0.0705  -0.0935 0.0345  422 ARG   A O   
229  C CB  . ARG   A 49  ? 0.5496 0.6039 0.7011 0.0831  -0.0931 0.0209  422 ARG   A CB  
230  C CG  . ARG   A 49  ? 0.5702 0.6715 0.7618 0.1005  -0.0958 0.0109  422 ARG   A CG  
231  C CD  . ARG   A 49  ? 0.6092 0.7554 0.8344 0.0934  -0.1070 0.0109  422 ARG   A CD  
232  N NE  . ARG   A 49  ? 0.6460 0.8429 0.9132 0.1125  -0.1104 -0.0001 422 ARG   A NE  
233  C CZ  . ARG   A 49  ? 0.6898 0.8793 0.9632 0.1395  -0.1267 -0.0054 422 ARG   A CZ  
234  N NH1 . ARG   A 49  ? 0.7107 0.8420 0.9474 0.1481  -0.1394 0.0017  422 ARG   A NH1 
235  N NH2 . ARG   A 49  ? 0.6562 0.8968 0.9721 0.1580  -0.1300 -0.0173 422 ARG   A NH2 
236  N N   . VAL   A 50  ? 0.5230 0.5045 0.6115 0.0518  -0.1071 0.0364  423 VAL   A N   
237  C CA  . VAL   A 50  ? 0.5206 0.4767 0.5852 0.0356  -0.0992 0.0401  423 VAL   A CA  
238  C C   . VAL   A 50  ? 0.5009 0.4835 0.5875 0.0196  -0.0879 0.0419  423 VAL   A C   
239  O O   . VAL   A 50  ? 0.5246 0.5408 0.6411 0.0120  -0.0927 0.0417  423 VAL   A O   
240  C CB  . VAL   A 50  ? 0.5479 0.4821 0.5922 0.0288  -0.1141 0.0410  423 VAL   A CB  
241  C CG1 . VAL   A 50  ? 0.5416 0.4538 0.5674 0.0136  -0.1066 0.0419  423 VAL   A CG1 
242  C CG2 . VAL   A 50  ? 0.5987 0.5047 0.6143 0.0422  -0.1239 0.0429  423 VAL   A CG2 
243  N N   . ALA   A 51  ? 0.4767 0.4430 0.5471 0.0127  -0.0741 0.0450  424 ALA   A N   
244  C CA  . ALA   A 51  ? 0.5017 0.4795 0.5830 -0.0048 -0.0667 0.0508  424 ALA   A CA  
245  C C   . ALA   A 51  ? 0.4593 0.4000 0.5166 -0.0141 -0.0707 0.0526  424 ALA   A C   
246  O O   . ALA   A 51  ? 0.4654 0.3781 0.4955 -0.0083 -0.0667 0.0511  424 ALA   A O   
247  C CB  . ALA   A 51  ? 0.5350 0.5289 0.6190 -0.0043 -0.0488 0.0533  424 ALA   A CB  
248  N N   . SER   A 52  ? 0.5015 0.4436 0.5711 -0.0286 -0.0788 0.0545  425 SER   A N   
249  C CA  . SER   A 52  ? 0.5264 0.4335 0.5765 -0.0358 -0.0839 0.0530  425 SER   A CA  
250  C C   . SER   A 52  ? 0.5356 0.4425 0.6004 -0.0531 -0.0807 0.0611  425 SER   A C   
251  O O   . SER   A 52  ? 0.5368 0.4710 0.6298 -0.0653 -0.0812 0.0668  425 SER   A O   
252  C CB  . SER   A 52  ? 0.5096 0.4061 0.5533 -0.0352 -0.1013 0.0444  425 SER   A CB  
253  O OG  . SER   A 52  ? 0.4957 0.4223 0.5698 -0.0427 -0.1109 0.0440  425 SER   A OG  
254  N N   . LEU   A 53  ? 0.5625 0.4376 0.6083 -0.0542 -0.0786 0.0618  426 LEU   A N   
255  C CA  . LEU   A 53  ? 0.5399 0.4047 0.5944 -0.0681 -0.0766 0.0716  426 LEU   A CA  
256  C C   . LEU   A 53  ? 0.5614 0.3866 0.6031 -0.0702 -0.0877 0.0636  426 LEU   A C   
257  O O   . LEU   A 53  ? 0.5516 0.3567 0.5690 -0.0578 -0.0876 0.0540  426 LEU   A O   
258  C CB  . LEU   A 53  ? 0.5404 0.4087 0.5848 -0.0626 -0.0615 0.0808  426 LEU   A CB  
259  C CG  . LEU   A 53  ? 0.6196 0.4714 0.6654 -0.0731 -0.0596 0.0939  426 LEU   A CG  
260  C CD1 . LEU   A 53  ? 0.6599 0.5310 0.7321 -0.0930 -0.0603 0.1071  426 LEU   A CD1 
261  C CD2 . LEU   A 53  ? 0.6446 0.5012 0.6756 -0.0646 -0.0468 0.1010  426 LEU   A CD2 
262  N N   . ASP   A 54  ? 0.5718 0.3871 0.6310 -0.0866 -0.0970 0.0663  427 ASP   A N   
263  C CA  . ASP   A 54  ? 0.6443 0.4201 0.6945 -0.0884 -0.1087 0.0561  427 ASP   A CA  
264  C C   . ASP   A 54  ? 0.6984 0.4484 0.7508 -0.0945 -0.1058 0.0687  427 ASP   A C   
265  O O   . ASP   A 54  ? 0.6958 0.4619 0.7552 -0.0992 -0.0949 0.0867  427 ASP   A O   
266  C CB  . ASP   A 54  ? 0.6451 0.4213 0.7111 -0.1011 -0.1248 0.0462  427 ASP   A CB  
267  C CG  . ASP   A 54  ? 0.6622 0.4515 0.7607 -0.1243 -0.1276 0.0589  427 ASP   A CG  
268  O OD1 . ASP   A 54  ? 0.7001 0.4758 0.8042 -0.1333 -0.1217 0.0744  427 ASP   A OD1 
269  O OD2 . ASP   A 54  ? 0.6880 0.5003 0.8058 -0.1342 -0.1370 0.0532  427 ASP   A OD2 
270  N N   . VAL   A 55  ? 0.6887 0.3990 0.7349 -0.0938 -0.1165 0.0587  428 VAL   A N   
271  C CA  . VAL   A 55  ? 0.7283 0.4072 0.7725 -0.0932 -0.1160 0.0688  428 VAL   A CA  
272  C C   . VAL   A 55  ? 0.7615 0.4306 0.8297 -0.1166 -0.1212 0.0869  428 VAL   A C   
273  O O   . VAL   A 55  ? 0.7476 0.3902 0.8157 -0.1188 -0.1218 0.1009  428 VAL   A O   
274  C CB  . VAL   A 55  ? 0.7440 0.3831 0.7739 -0.0803 -0.1256 0.0491  428 VAL   A CB  
275  C CG1 . VAL   A 55  ? 0.7434 0.3942 0.7487 -0.0591 -0.1174 0.0351  428 VAL   A CG1 
276  C CG2 . VAL   A 55  ? 0.7489 0.3668 0.7873 -0.0901 -0.1426 0.0313  428 VAL   A CG2 
277  N N   . ASP   A 56  ? 0.7414 0.4321 0.8304 -0.1345 -0.1257 0.0873  429 ASP   A N   
278  C CA  . ASP   A 56  ? 0.7467 0.4391 0.8608 -0.1607 -0.1274 0.1070  429 ASP   A CA  
279  C C   . ASP   A 56  ? 0.7182 0.4591 0.8404 -0.1669 -0.1103 0.1280  429 ASP   A C   
280  O O   . ASP   A 56  ? 0.7681 0.5276 0.9131 -0.1902 -0.1085 0.1436  429 ASP   A O   
281  C CB  . ASP   A 56  ? 0.7818 0.4797 0.9188 -0.1794 -0.1410 0.0956  429 ASP   A CB  
282  C CG  . ASP   A 56  ? 0.8714 0.5194 1.0064 -0.1811 -0.1600 0.0757  429 ASP   A CG  
283  O OD1 . ASP   A 56  ? 0.9236 0.5291 1.0420 -0.1680 -0.1627 0.0722  429 ASP   A OD1 
284  O OD2 . ASP   A 56  ? 0.9346 0.5892 1.0857 -0.1945 -0.1728 0.0618  429 ASP   A OD2 
285  N N   . GLY   A 57  ? 0.6996 0.4652 0.8046 -0.1472 -0.0976 0.1260  430 GLY   A N   
286  C CA  . GLY   A 57  ? 0.6970 0.5110 0.8083 -0.1501 -0.0813 0.1407  430 GLY   A CA  
287  C C   . GLY   A 57  ? 0.6798 0.5421 0.8154 -0.1586 -0.0797 0.1353  430 GLY   A C   
288  O O   . GLY   A 57  ? 0.6827 0.5882 0.8318 -0.1668 -0.0671 0.1480  430 GLY   A O   
289  N N   . VAL   A 58  ? 0.6351 0.4943 0.7767 -0.1559 -0.0927 0.1161  431 VAL   A N   
290  C CA  . VAL   A 58  ? 0.6289 0.5357 0.7923 -0.1579 -0.0931 0.1091  431 VAL   A CA  
291  C C   . VAL   A 58  ? 0.6233 0.5509 0.7708 -0.1326 -0.0847 0.1002  431 VAL   A C   
292  O O   . VAL   A 58  ? 0.5770 0.4782 0.6994 -0.1153 -0.0889 0.0882  431 VAL   A O   
293  C CB  . VAL   A 58  ? 0.6516 0.5527 0.8290 -0.1658 -0.1121 0.0934  431 VAL   A CB  
294  C CG1 . VAL   A 58  ? 0.6421 0.5992 0.8472 -0.1681 -0.1128 0.0890  431 VAL   A CG1 
295  C CG2 . VAL   A 58  ? 0.6845 0.5548 0.8766 -0.1913 -0.1228 0.0988  431 VAL   A CG2 
296  N N   . ILE   A 59  ? 0.6157 0.5907 0.7781 -0.1316 -0.0721 0.1062  432 ILE   A N   
297  C CA  . ILE   A 59  ? 0.5977 0.5937 0.7514 -0.1091 -0.0659 0.0966  432 ILE   A CA  
298  C C   . ILE   A 59  ? 0.5787 0.6097 0.7576 -0.1071 -0.0750 0.0862  432 ILE   A C   
299  O O   . ILE   A 59  ? 0.5442 0.6098 0.7549 -0.1240 -0.0760 0.0905  432 ILE   A O   
300  C CB  . ILE   A 59  ? 0.6637 0.6891 0.8163 -0.1054 -0.0466 0.1061  432 ILE   A CB  
301  C CG1 . ILE   A 59  ? 0.6776 0.6696 0.8008 -0.1006 -0.0398 0.1132  432 ILE   A CG1 
302  C CG2 . ILE   A 59  ? 0.7044 0.7606 0.8602 -0.0851 -0.0416 0.0940  432 ILE   A CG2 
303  N N   . LYS   A 60  ? 0.5728 0.5944 0.7370 -0.0870 -0.0826 0.0732  433 LYS   A N   
304  C CA  . LYS   A 60  ? 0.5391 0.5918 0.7232 -0.0792 -0.0933 0.0636  433 LYS   A CA  
305  C C   . LYS   A 60  ? 0.5217 0.5814 0.6940 -0.0539 -0.0876 0.0580  433 LYS   A C   
306  O O   . LYS   A 60  ? 0.5271 0.5523 0.6675 -0.0425 -0.0836 0.0570  433 LYS   A O   
307  C CB  . LYS   A 60  ? 0.5611 0.5904 0.7368 -0.0795 -0.1141 0.0536  433 LYS   A CB  
308  C CG  . LYS   A 60  ? 0.5875 0.6003 0.7721 -0.1026 -0.1240 0.0540  433 LYS   A CG  
309  C CD  . LYS   A 60  ? 0.6041 0.6601 0.8309 -0.1207 -0.1309 0.0543  433 LYS   A CD  
310  C CE  . LYS   A 60  ? 0.6366 0.6688 0.8708 -0.1444 -0.1438 0.0521  433 LYS   A CE  
311  N NZ  . LYS   A 60  ? 0.6385 0.7168 0.9147 -0.1615 -0.1528 0.0497  433 LYS   A NZ  
312  N N   . VAL   A 61  ? 0.5083 0.6134 0.7090 -0.0458 -0.0880 0.0536  434 VAL   A N   
313  C CA  . VAL   A 61  ? 0.4889 0.6006 0.6847 -0.0205 -0.0867 0.0464  434 VAL   A CA  
314  C C   . VAL   A 61  ? 0.4817 0.6131 0.6961 -0.0104 -0.1056 0.0386  434 VAL   A C   
315  O O   . VAL   A 61  ? 0.5017 0.6771 0.7526 -0.0197 -0.1104 0.0370  434 VAL   A O   
316  C CB  . VAL   A 61  ? 0.4788 0.6306 0.6931 -0.0158 -0.0680 0.0463  434 VAL   A CB  
317  C CG1 . VAL   A 61  ? 0.4632 0.6198 0.6762 0.0116  -0.0678 0.0361  434 VAL   A CG1 
318  C CG2 . VAL   A 61  ? 0.4686 0.6046 0.6633 -0.0267 -0.0510 0.0554  434 VAL   A CG2 
319  N N   . TRP   A 62  ? 0.4995 0.6000 0.6887 0.0083  -0.1164 0.0349  435 TRP   A N   
320  C CA  . TRP   A 62  ? 0.5052 0.6153 0.7029 0.0186  -0.1381 0.0299  435 TRP   A CA  
321  C C   . TRP   A 62  ? 0.5215 0.6099 0.6997 0.0452  -0.1440 0.0284  435 TRP   A C   
322  O O   . TRP   A 62  ? 0.5253 0.5751 0.6717 0.0508  -0.1350 0.0314  435 TRP   A O   
323  C CB  . TRP   A 62  ? 0.5117 0.5970 0.6921 0.0039  -0.1533 0.0298  435 TRP   A CB  
324  C CG  . TRP   A 62  ? 0.5107 0.5434 0.6483 -0.0016 -0.1474 0.0329  435 TRP   A CG  
325  C CD1 . TRP   A 62  ? 0.5036 0.5204 0.6344 -0.0166 -0.1330 0.0369  435 TRP   A CD1 
326  C CD2 . TRP   A 62  ? 0.5331 0.5259 0.6302 0.0069  -0.1569 0.0320  435 TRP   A CD2 
327  N NE1 . TRP   A 62  ? 0.5150 0.4872 0.6071 -0.0157 -0.1327 0.0366  435 TRP   A NE1 
328  C CE2 . TRP   A 62  ? 0.5125 0.4708 0.5831 -0.0029 -0.1461 0.0333  435 TRP   A CE2 
329  C CE3 . TRP   A 62  ? 0.5414 0.5257 0.6213 0.0220  -0.1735 0.0313  435 TRP   A CE3 
330  C CZ2 . TRP   A 62  ? 0.5411 0.4621 0.5711 0.0011  -0.1492 0.0320  435 TRP   A CZ2 
331  C CZ3 . TRP   A 62  ? 0.5565 0.5008 0.5922 0.0243  -0.1765 0.0327  435 TRP   A CZ3 
332  C CH2 . TRP   A 62  ? 0.5576 0.4731 0.5697 0.0134  -0.1637 0.0320  435 TRP   A CH2 
333  N N   . SER   A 63  ? 0.5747 0.6898 0.7749 0.0613  -0.1600 0.0241  436 SER   A N   
334  C CA  . SER   A 63  ? 0.5793 0.6679 0.7596 0.0857  -0.1730 0.0254  436 SER   A CA  
335  C C   . SER   A 63  ? 0.6286 0.6936 0.7820 0.0826  -0.1945 0.0292  436 SER   A C   
336  O O   . SER   A 63  ? 0.6327 0.7108 0.7924 0.0641  -0.2012 0.0268  436 SER   A O   
337  C CB  . SER   A 63  ? 0.5510 0.6801 0.7693 0.1080  -0.1799 0.0187  436 SER   A CB  
338  O OG  . SER   A 63  ? 0.5124 0.6942 0.7697 0.1007  -0.1912 0.0138  436 SER   A OG  
339  N N   . PHE   A 64  ? 0.6335 0.6641 0.7570 0.1005  -0.2058 0.0351  437 PHE   A N   
340  C CA  . PHE   A 64  ? 0.6179 0.6216 0.7051 0.0979  -0.2237 0.0404  437 PHE   A CA  
341  C C   . PHE   A 64  ? 0.6465 0.6394 0.7235 0.1228  -0.2443 0.0474  437 PHE   A C   
342  O O   . PHE   A 64  ? 0.7059 0.6858 0.7557 0.1237  -0.2632 0.0528  437 PHE   A O   
343  C CB  . PHE   A 64  ? 0.5977 0.5543 0.6398 0.0854  -0.2096 0.0452  437 PHE   A CB  
344  C CG  . PHE   A 64  ? 0.6142 0.5413 0.6423 0.0946  -0.1929 0.0499  437 PHE   A CG  
345  C CD1 . PHE   A 64  ? 0.6794 0.5712 0.6787 0.1095  -0.2004 0.0593  437 PHE   A CD1 
346  C CD2 . PHE   A 64  ? 0.6075 0.5416 0.6505 0.0871  -0.1706 0.0454  437 PHE   A CD2 
347  C CE1 . PHE   A 64  ? 0.7063 0.5695 0.6949 0.1154  -0.1858 0.0621  437 PHE   A CE1 
348  C CE2 . PHE   A 64  ? 0.6168 0.5258 0.6473 0.0943  -0.1564 0.0472  437 PHE   A CE2 
349  C CZ  . PHE   A 64  ? 0.6628 0.5361 0.6678 0.1080  -0.1639 0.0545  437 PHE   A CZ  
350  N N   . ASN   A 65  ? 0.6138 0.6122 0.7123 0.1437  -0.2417 0.0469  438 ASN   A N   
351  C CA  . ASN   A 65  ? 0.6353 0.6161 0.7245 0.1695  -0.2619 0.0549  438 ASN   A CA  
352  C C   . ASN   A 65  ? 0.6398 0.6725 0.7833 0.1895  -0.2725 0.0454  438 ASN   A C   
353  O O   . ASN   A 65  ? 0.6278 0.6791 0.8019 0.1968  -0.2566 0.0362  438 ASN   A O   
354  C CB  . ASN   A 65  ? 0.6340 0.5610 0.6935 0.1789  -0.2514 0.0633  438 ASN   A CB  
355  C CG  . ASN   A 65  ? 0.6960 0.5954 0.7423 0.2044  -0.2735 0.0748  438 ASN   A CG  
356  O OD1 . ASN   A 65  ? 0.7004 0.6107 0.7426 0.2126  -0.2986 0.0811  438 ASN   A OD1 
357  N ND2 . ASN   A 65  ? 0.7114 0.5736 0.7510 0.2175  -0.2660 0.0778  438 ASN   A ND2 
358  N N   . PRO   A 66  ? 0.6450 0.7072 0.8033 0.1996  -0.2995 0.0458  439 PRO   A N   
359  C CA  . PRO   A 66  ? 0.6823 0.7223 0.7999 0.1949  -0.3211 0.0566  439 PRO   A CA  
360  C C   . PRO   A 66  ? 0.7062 0.7648 0.8167 0.1664  -0.3223 0.0507  439 PRO   A C   
361  O O   . PRO   A 66  ? 0.7373 0.7722 0.8055 0.1595  -0.3354 0.0576  439 PRO   A O   
362  C CB  . PRO   A 66  ? 0.7021 0.7716 0.8464 0.2226  -0.3501 0.0574  439 PRO   A CB  
363  C CG  . PRO   A 66  ? 0.6664 0.8034 0.8776 0.2252  -0.3433 0.0398  439 PRO   A CG  
364  C CD  . PRO   A 66  ? 0.6308 0.7556 0.8475 0.2161  -0.3102 0.0343  439 PRO   A CD  
365  N N   . ILE   A 67  ? 0.6676 0.7707 0.8204 0.1502  -0.3103 0.0375  440 ILE   A N   
366  C CA  . ILE   A 67  ? 0.6683 0.7804 0.8158 0.1212  -0.3086 0.0310  440 ILE   A CA  
367  C C   . ILE   A 67  ? 0.6263 0.7367 0.7853 0.1004  -0.2791 0.0264  440 ILE   A C   
368  O O   . ILE   A 67  ? 0.5840 0.7038 0.7652 0.1072  -0.2611 0.0255  440 ILE   A O   
369  C CB  . ILE   A 67  ? 0.6439 0.8131 0.8307 0.1164  -0.3304 0.0209  440 ILE   A CB  
370  C CG1 . ILE   A 67  ? 0.6129 0.8417 0.8641 0.1234  -0.3249 0.0126  440 ILE   A CG1 
371  C CG2 . ILE   A 67  ? 0.6955 0.8622 0.8601 0.1334  -0.3623 0.0262  440 ILE   A CG2 
372  C CD1 . ILE   A 67  ? 0.5970 0.8883 0.8934 0.1104  -0.3412 0.0011  440 ILE   A CD1 
373  N N   . MET   A 68  ? 0.6380 0.7380 0.7819 0.0757  -0.2762 0.0226  441 MET   A N   
374  C CA  . MET   A 68  ? 0.6355 0.7357 0.7915 0.0537  -0.2533 0.0192  441 MET   A CA  
375  C C   . MET   A 68  ? 0.5986 0.7570 0.8120 0.0435  -0.2520 0.0122  441 MET   A C   
376  O O   . MET   A 68  ? 0.6228 0.8132 0.8580 0.0363  -0.2706 0.0055  441 MET   A O   
377  C CB  . MET   A 68  ? 0.6526 0.7215 0.7759 0.0333  -0.2548 0.0160  441 MET   A CB  
378  C CG  . MET   A 68  ? 0.6941 0.7111 0.7688 0.0376  -0.2421 0.0228  441 MET   A CG  
379  S SD  . MET   A 68  ? 0.8150 0.7976 0.8418 0.0249  -0.2513 0.0172  441 MET   A SD  
380  C CE  . MET   A 68  ? 0.7687 0.7033 0.7502 0.0338  -0.2314 0.0278  441 MET   A CE  
381  N N   . GLN   A 69  ? 0.5896 0.7655 0.8275 0.0429  -0.2302 0.0134  442 GLN   A N   
382  C CA  . GLN   A 69  ? 0.6089 0.8362 0.8950 0.0243  -0.2229 0.0089  442 GLN   A CA  
383  C C   . GLN   A 69  ? 0.5743 0.7935 0.8602 0.0115  -0.1944 0.0141  442 GLN   A C   
384  O O   . GLN   A 69  ? 0.5528 0.7447 0.8157 0.0249  -0.1801 0.0180  442 GLN   A O   
385  C CB  . GLN   A 69  ? 0.6584 0.9472 0.9919 0.0401  -0.2340 0.0025  442 GLN   A CB  
386  C CG  . GLN   A 69  ? 0.6918 1.0007 1.0436 0.0614  -0.2178 0.0016  442 GLN   A CG  
387  C CD  . GLN   A 69  ? 0.7894 1.1514 1.1824 0.0856  -0.2332 -0.0064 442 GLN   A CD  
388  O OE1 . GLN   A 69  ? 0.8482 1.2236 1.2552 0.1099  -0.2253 -0.0103 442 GLN   A OE1 
389  N NE2 . GLN   A 69  ? 0.8082 1.2005 1.2212 0.0810  -0.2569 -0.0107 442 GLN   A NE2 
390  N N   . THR   A 70  ? 0.5410 0.7807 0.8501 -0.0164 -0.1880 0.0147  443 THR   A N   
391  C CA  . THR   A 70  ? 0.5377 0.7707 0.8459 -0.0332 -0.1640 0.0223  443 THR   A CA  
392  C C   . THR   A 70  ? 0.5235 0.8133 0.8700 -0.0284 -0.1479 0.0220  443 THR   A C   
393  O O   . THR   A 70  ? 0.5826 0.9286 0.9719 -0.0323 -0.1542 0.0167  443 THR   A O   
394  C CB  . THR   A 70  ? 0.5305 0.7569 0.8466 -0.0655 -0.1674 0.0245  443 THR   A CB  
395  O OG1 . THR   A 70  ? 0.5424 0.7212 0.8229 -0.0635 -0.1839 0.0199  443 THR   A OG1 
396  C CG2 . THR   A 70  ? 0.5346 0.7453 0.8446 -0.0839 -0.1456 0.0357  443 THR   A CG2 
397  N N   . LYS   A 71  ? 0.5639 0.8428 0.8953 -0.0202 -0.1273 0.0260  444 LYS   A N   
398  C CA  . LYS   A 71  ? 0.5749 0.9085 0.9380 -0.0139 -0.1103 0.0231  444 LYS   A CA  
399  C C   . LYS   A 71  ? 0.5730 0.9233 0.9439 -0.0417 -0.0896 0.0337  444 LYS   A C   
400  O O   . LYS   A 71  ? 0.5976 1.0086 1.0047 -0.0490 -0.0778 0.0329  444 LYS   A O   
401  C CB  . LYS   A 71  ? 0.5941 0.9092 0.9366 0.0149  -0.1016 0.0182  444 LYS   A CB  
402  C CG  . LYS   A 71  ? 0.6675 0.9649 1.0025 0.0443  -0.1209 0.0105  444 LYS   A CG  
403  C CD  . LYS   A 71  ? 0.6873 1.0442 1.0685 0.0614  -0.1318 -0.0002 444 LYS   A CD  
404  C CE  . LYS   A 71  ? 0.7132 1.0428 1.0813 0.0916  -0.1525 -0.0042 444 LYS   A CE  
405  N NZ  . LYS   A 71  ? 0.7187 1.1042 1.1321 0.1123  -0.1654 -0.0150 444 LYS   A NZ  
406  N N   . ALA   A 72  ? 0.5637 0.8613 0.8998 -0.0562 -0.0851 0.0441  445 ALA   A N   
407  C CA  . ALA   A 72  ? 0.5938 0.8985 0.9328 -0.0827 -0.0686 0.0577  445 ALA   A CA  
408  C C   . ALA   A 72  ? 0.6296 0.8778 0.9443 -0.1024 -0.0771 0.0665  445 ALA   A C   
409  O O   . ALA   A 72  ? 0.6008 0.7967 0.8821 -0.0909 -0.0866 0.0627  445 ALA   A O   
410  C CB  . ALA   A 72  ? 0.5645 0.8713 0.8856 -0.0725 -0.0469 0.0609  445 ALA   A CB  
411  N N   . SER   A 73  ? 0.6634 0.9229 0.9962 -0.1325 -0.0736 0.0780  446 SER   A N   
412  C CA  . SER   A 73  ? 0.7033 0.9075 1.0154 -0.1510 -0.0802 0.0865  446 SER   A CA  
413  C C   . SER   A 73  ? 0.7351 0.9457 1.0523 -0.1761 -0.0642 0.1064  446 SER   A C   
414  O O   . SER   A 73  ? 0.7695 1.0329 1.1202 -0.1939 -0.0560 0.1130  446 SER   A O   
415  C CB  . SER   A 73  ? 0.6693 0.8665 0.9978 -0.1644 -0.1019 0.0785  446 SER   A CB  
416  O OG  . SER   A 73  ? 0.6730 0.8053 0.9716 -0.1690 -0.1120 0.0782  446 SER   A OG  
417  N N   . SER   A 74  ? 0.8178 0.9781 1.1014 -0.1763 -0.0593 0.1166  447 SER   A N   
418  C CA  . SER   A 74  ? 0.8443 1.0011 1.1279 -0.2004 -0.0477 0.1386  447 SER   A CA  
419  C C   . SER   A 74  ? 0.8470 0.9320 1.1019 -0.2047 -0.0566 0.1454  447 SER   A C   
420  O O   . SER   A 74  ? 0.7563 0.8018 0.9834 -0.1834 -0.0634 0.1337  447 SER   A O   
421  C CB  . SER   A 74  ? 0.8546 1.0474 1.1305 -0.1931 -0.0253 0.1477  447 SER   A CB  
422  O OG  . SER   A 74  ? 0.8943 1.0599 1.1360 -0.1660 -0.0216 0.1403  447 SER   A OG  
423  N N   . ILE   A 75  ? 0.8756 0.9456 1.1402 -0.2335 -0.0573 0.1639  448 ILE   A N   
424  C CA  . ILE   A 75  ? 0.8908 0.8949 1.1316 -0.2386 -0.0640 0.1743  448 ILE   A CA  
425  C C   . ILE   A 75  ? 0.8447 0.8516 1.0655 -0.2376 -0.0469 0.1959  448 ILE   A C   
426  O O   . ILE   A 75  ? 0.8537 0.9014 1.0885 -0.2563 -0.0335 0.2143  448 ILE   A O   
427  C CB  . ILE   A 75  ? 0.9717 0.9497 1.2340 -0.2704 -0.0771 0.1827  448 ILE   A CB  
428  C CG1 . ILE   A 75  ? 0.9976 1.0111 1.2956 -0.2830 -0.0879 0.1672  448 ILE   A CG1 
429  C CG2 . ILE   A 75  ? 0.9666 0.8675 1.2062 -0.2656 -0.0925 0.1787  448 ILE   A CG2 
430  N N   . SER   A 76  ? 0.7720 0.7384 0.9598 -0.2169 -0.0477 0.1939  449 SER   A N   
431  C CA  . SER   A 76  ? 0.8146 0.7774 0.9812 -0.2159 -0.0356 0.2145  449 SER   A CA  
432  C C   . SER   A 76  ? 0.9110 0.8261 1.0752 -0.2368 -0.0439 0.2373  449 SER   A C   
433  O O   . SER   A 76  ? 0.9520 0.8125 1.1125 -0.2345 -0.0603 0.2292  449 SER   A O   
434  C CB  . SER   A 76  ? 0.7849 0.7297 0.9212 -0.1861 -0.0336 0.2026  449 SER   A CB  
435  O OG  . SER   A 76  ? 0.8041 0.7617 0.9220 -0.1839 -0.0206 0.2201  449 SER   A OG  
436  N N   . LYS   A 77  ? 0.9325 0.8676 1.0975 -0.2567 -0.0326 0.2657  450 LYS   A N   
437  C CA  . LYS   A 77  ? 1.0749 0.9610 1.2338 -0.2756 -0.0403 0.2922  450 LYS   A CA  
438  C C   . LYS   A 77  ? 1.1100 0.9481 1.2357 -0.2506 -0.0461 0.2932  450 LYS   A C   
439  O O   . LYS   A 77  ? 1.1514 0.9273 1.2721 -0.2505 -0.0619 0.2965  450 LYS   A O   
440  C CB  . LYS   A 77  ? 1.0861 1.0103 1.2517 -0.3046 -0.0258 0.3251  450 LYS   A CB  
441  N N   . SER   A 78  ? 1.0361 0.9051 1.1414 -0.2281 -0.0339 0.2873  451 SER   A N   
442  C CA  . SER   A 78  ? 0.9981 0.8340 1.0747 -0.2038 -0.0380 0.2860  451 SER   A CA  
443  C C   . SER   A 78  ? 0.9594 0.7771 1.0316 -0.1780 -0.0457 0.2527  451 SER   A C   
444  O O   . SER   A 78  ? 0.8574 0.7033 0.9409 -0.1734 -0.0425 0.2320  451 SER   A O   
445  C CB  . SER   A 78  ? 0.9983 0.8766 1.0550 -0.1958 -0.0221 0.2966  451 SER   A CB  
446  O OG  . SER   A 78  ? 1.1531 1.0587 1.2131 -0.2216 -0.0125 0.3268  451 SER   A OG  
447  N N   . PRO   A 79  ? 0.9612 0.7336 1.0161 -0.1596 -0.0558 0.2472  452 PRO   A N   
448  C CA  . PRO   A 79  ? 0.8446 0.6061 0.8919 -0.1357 -0.0602 0.2172  452 PRO   A CA  
449  C C   . PRO   A 79  ? 0.7987 0.6069 0.8368 -0.1209 -0.0459 0.2043  452 PRO   A C   
450  O O   . PRO   A 79  ? 0.7650 0.6008 0.7914 -0.1183 -0.0348 0.2164  452 PRO   A O   
451  C CB  . PRO   A 79  ? 0.8862 0.6005 0.9177 -0.1198 -0.0706 0.2184  452 PRO   A CB  
452  C CG  . PRO   A 79  ? 0.9768 0.6865 1.0018 -0.1307 -0.0692 0.2518  452 PRO   A CG  
453  C CD  . PRO   A 79  ? 0.9878 0.7177 1.0312 -0.1611 -0.0644 0.2701  452 PRO   A CD  
454  N N   . LEU   A 80  ? 0.7565 0.5703 0.7981 -0.1110 -0.0475 0.1795  453 LEU   A N   
455  C CA  . LEU   A 80  ? 0.6551 0.5018 0.6881 -0.0955 -0.0370 0.1646  453 LEU   A CA  
456  C C   . LEU   A 80  ? 0.6263 0.4468 0.6431 -0.0759 -0.0424 0.1453  453 LEU   A C   
457  O O   . LEU   A 80  ? 0.6451 0.4363 0.6640 -0.0745 -0.0535 0.1337  453 LEU   A O   
458  C CB  . LEU   A 80  ? 0.6513 0.5295 0.7026 -0.1012 -0.0346 0.1547  453 LEU   A CB  
459  C CG  . LEU   A 80  ? 0.6631 0.5840 0.7327 -0.1185 -0.0249 0.1699  453 LEU   A CG  
460  C CD1 . LEU   A 80  ? 0.6290 0.5864 0.7188 -0.1182 -0.0229 0.1561  453 LEU   A CD1 
461  C CD2 . LEU   A 80  ? 0.6662 0.6142 0.7216 -0.1146 -0.0107 0.1813  453 LEU   A CD2 
462  N N   . LEU   A 81  ? 0.6108 0.4445 0.6116 -0.0618 -0.0340 0.1413  454 LEU   A N   
463  C CA  . LEU   A 81  ? 0.6025 0.4159 0.5884 -0.0453 -0.0372 0.1254  454 LEU   A CA  
464  C C   . LEU   A 81  ? 0.5594 0.3931 0.5382 -0.0357 -0.0297 0.1089  454 LEU   A C   
465  O O   . LEU   A 81  ? 0.5737 0.3936 0.5412 -0.0250 -0.0315 0.0948  454 LEU   A O   
466  C CB  . LEU   A 81  ? 0.5971 0.4046 0.5711 -0.0375 -0.0363 0.1346  454 LEU   A CB  
467  C CG  . LEU   A 81  ? 0.6796 0.4588 0.6578 -0.0441 -0.0460 0.1528  454 LEU   A CG  
468  C CD1 . LEU   A 81  ? 0.7004 0.4756 0.6653 -0.0306 -0.0470 0.1582  454 LEU   A CD1 
469  C CD2 . LEU   A 81  ? 0.7088 0.4481 0.6955 -0.0460 -0.0595 0.1440  454 LEU   A CD2 
470  N N   . SER   A 82  ? 0.5207 0.3876 0.5055 -0.0388 -0.0206 0.1111  455 SER   A N   
471  C CA  . SER   A 82  ? 0.5099 0.3916 0.4867 -0.0283 -0.0136 0.0972  455 SER   A CA  
472  C C   . SER   A 82  ? 0.4744 0.3858 0.4651 -0.0312 -0.0084 0.0957  455 SER   A C   
473  O O   . SER   A 82  ? 0.5044 0.4369 0.5091 -0.0414 -0.0056 0.1069  455 SER   A O   
474  C CB  . SER   A 82  ? 0.5080 0.3990 0.4707 -0.0207 -0.0060 0.0963  455 SER   A CB  
475  O OG  . SER   A 82  ? 0.5661 0.4827 0.5310 -0.0263 0.0005  0.1097  455 SER   A OG  
476  N N   . LEU   A 83  ? 0.4707 0.3841 0.4573 -0.0218 -0.0070 0.0822  456 LEU   A N   
477  C CA  . LEU   A 83  ? 0.4735 0.4104 0.4747 -0.0198 -0.0051 0.0772  456 LEU   A CA  
478  C C   . LEU   A 83  ? 0.4483 0.3842 0.4393 -0.0071 -0.0008 0.0642  456 LEU   A C   
479  O O   . LEU   A 83  ? 0.4521 0.3628 0.4262 -0.0024 -0.0032 0.0583  456 LEU   A O   
480  C CB  . LEU   A 83  ? 0.5421 0.4635 0.5520 -0.0245 -0.0176 0.0766  456 LEU   A CB  
481  C CG  . LEU   A 83  ? 0.5236 0.4564 0.5459 -0.0194 -0.0231 0.0690  456 LEU   A CG  
482  C CD1 . LEU   A 83  ? 0.5236 0.4461 0.5558 -0.0289 -0.0361 0.0710  456 LEU   A CD1 
483  C CD2 . LEU   A 83  ? 0.5141 0.4290 0.5192 -0.0065 -0.0247 0.0587  456 LEU   A CD2 
484  N N   . GLU   A 84  ? 0.4207 0.3848 0.4227 -0.0021 0.0059  0.0593  457 GLU   A N   
485  C CA  . GLU   A 84  ? 0.4245 0.3848 0.4191 0.0095  0.0092  0.0463  457 GLU   A CA  
486  C C   . GLU   A 84  ? 0.4546 0.4446 0.4692 0.0169  0.0122  0.0392  457 GLU   A C   
487  O O   . GLU   A 84  ? 0.4680 0.4937 0.4950 0.0132  0.0203  0.0418  457 GLU   A O   
488  C CB  . GLU   A 84  ? 0.4598 0.4226 0.4391 0.0099  0.0180  0.0437  457 GLU   A CB  
489  C CG  . GLU   A 84  ? 0.4578 0.4202 0.4322 0.0197  0.0227  0.0286  457 GLU   A CG  
490  C CD  . GLU   A 84  ? 0.4893 0.4149 0.4496 0.0229  0.0173  0.0229  457 GLU   A CD  
491  O OE1 . GLU   A 84  ? 0.5005 0.4038 0.4554 0.0198  0.0093  0.0290  457 GLU   A OE1 
492  O OE2 . GLU   A 84  ? 0.4603 0.3803 0.4144 0.0277  0.0211  0.0116  457 GLU   A OE2 
493  N N   . TRP   A 85  ? 0.4594 0.4351 0.4768 0.0277  0.0053  0.0308  458 TRP   A N   
494  C CA  . TRP   A 85  ? 0.4375 0.4371 0.4749 0.0397  0.0060  0.0209  458 TRP   A CA  
495  C C   . TRP   A 85  ? 0.4521 0.4595 0.4838 0.0479  0.0164  0.0081  458 TRP   A C   
496  O O   . TRP   A 85  ? 0.4877 0.4674 0.4989 0.0478  0.0176  0.0045  458 TRP   A O   
497  C CB  . TRP   A 85  ? 0.4513 0.4261 0.4901 0.0506  -0.0072 0.0176  458 TRP   A CB  
498  C CG  . TRP   A 85  ? 0.4325 0.4098 0.4821 0.0455  -0.0192 0.0259  458 TRP   A CG  
499  C CD1 . TRP   A 85  ? 0.4460 0.3932 0.4793 0.0388  -0.0292 0.0330  458 TRP   A CD1 
500  C CD2 . TRP   A 85  ? 0.4222 0.4374 0.5025 0.0467  -0.0229 0.0256  458 TRP   A CD2 
501  N NE1 . TRP   A 85  ? 0.4516 0.4129 0.5020 0.0358  -0.0401 0.0364  458 TRP   A NE1 
502  C CE2 . TRP   A 85  ? 0.4279 0.4313 0.5086 0.0397  -0.0366 0.0327  458 TRP   A CE2 
503  C CE3 . TRP   A 85  ? 0.4228 0.4841 0.5310 0.0530  -0.0157 0.0184  458 TRP   A CE3 
504  C CZ2 . TRP   A 85  ? 0.4291 0.4648 0.5386 0.0376  -0.0443 0.0332  458 TRP   A CZ2 
505  C CZ3 . TRP   A 85  ? 0.4179 0.5137 0.5558 0.0514  -0.0221 0.0195  458 TRP   A CZ3 
506  C CH2 . TRP   A 85  ? 0.4242 0.5067 0.5634 0.0434  -0.0369 0.0271  458 TRP   A CH2 
507  N N   . ALA   A 86  ? 0.4323 0.4802 0.4834 0.0542  0.0238  -0.0002 459 ALA   A N   
508  C CA  . ALA   A 86  ? 0.4674 0.5259 0.5169 0.0652  0.0321  -0.0177 459 ALA   A CA  
509  C C   . ALA   A 86  ? 0.5087 0.5311 0.5573 0.0808  0.0229  -0.0296 459 ALA   A C   
510  O O   . ALA   A 86  ? 0.5238 0.5351 0.5836 0.0876  0.0116  -0.0259 459 ALA   A O   
511  C CB  . ALA   A 86  ? 0.4723 0.5866 0.5453 0.0698  0.0417  -0.0253 459 ALA   A CB  
512  N N   . THR   A 87  ? 0.5119 0.5203 0.5494 0.0869  0.0275  -0.0446 460 THR   A N   
513  C CA  . THR   A 87  ? 0.5701 0.5360 0.6038 0.0991  0.0187  -0.0543 460 THR   A CA  
514  C C   . THR   A 87  ? 0.6122 0.5947 0.6689 0.1203  0.0182  -0.0740 460 THR   A C   
515  O O   . THR   A 87  ? 0.6944 0.6443 0.7559 0.1339  0.0067  -0.0777 460 THR   A O   
516  C CB  . THR   A 87  ? 0.5897 0.5261 0.5996 0.0912  0.0224  -0.0596 460 THR   A CB  
517  O OG1 . THR   A 87  ? 0.5449 0.5194 0.5550 0.0890  0.0349  -0.0710 460 THR   A OG1 
518  C CG2 . THR   A 87  ? 0.5311 0.4426 0.5205 0.0747  0.0195  -0.0416 460 THR   A CG2 
519  N N   . LYS   A 88  ? 0.6199 0.6534 0.6903 0.1241  0.0302  -0.0867 461 LYS   A N   
520  C CA  . LYS   A 88  ? 0.6309 0.6827 0.7229 0.1462  0.0314  -0.1108 461 LYS   A CA  
521  C C   . LYS   A 88  ? 0.6353 0.7467 0.7578 0.1531  0.0356  -0.1120 461 LYS   A C   
522  O O   . LYS   A 88  ? 0.6533 0.7885 0.7990 0.1738  0.0366  -0.1328 461 LYS   A O   
523  C CB  . LYS   A 88  ? 0.6681 0.7321 0.7513 0.1492  0.0428  -0.1339 461 LYS   A CB  
524  C CG  . LYS   A 88  ? 0.7334 0.7397 0.7958 0.1478  0.0372  -0.1421 461 LYS   A CG  
525  C CD  . LYS   A 88  ? 0.7964 0.7474 0.8646 0.1625  0.0216  -0.1445 461 LYS   A CD  
526  C CE  . LYS   A 88  ? 0.8707 0.7700 0.9208 0.1590  0.0185  -0.1556 461 LYS   A CE  
527  N NZ  . LYS   A 88  ? 0.9372 0.7879 0.9968 0.1775  0.0047  -0.1641 461 LYS   A NZ  
528  N N   . ARG   A 89  ? 0.6467 0.7819 0.7712 0.1360  0.0376  -0.0909 462 ARG   A N   
529  C CA  . ARG   A 89  ? 0.6565 0.8423 0.8127 0.1391  0.0383  -0.0882 462 ARG   A CA  
530  C C   . ARG   A 89  ? 0.6143 0.7807 0.7700 0.1261  0.0260  -0.0646 462 ARG   A C   
531  O O   . ARG   A 89  ? 0.5680 0.7440 0.7148 0.1047  0.0307  -0.0472 462 ARG   A O   
532  C CB  . ARG   A 89  ? 0.6989 0.9507 0.8631 0.1269  0.0565  -0.0875 462 ARG   A CB  
533  C CG  . ARG   A 89  ? 0.8160 1.0959 0.9741 0.1350  0.0712  -0.1099 462 ARG   A CG  
534  C CD  . ARG   A 89  ? 0.8694 1.1889 1.0585 0.1601  0.0746  -0.1373 462 ARG   A CD  
535  N NE  . ARG   A 89  ? 0.9527 1.3037 1.1321 0.1650  0.0902  -0.1595 462 ARG   A NE  
536  C CZ  . ARG   A 89  ? 1.0321 1.4450 1.2089 0.1521  0.1082  -0.1574 462 ARG   A CZ  
537  N NH1 . ARG   A 89  ? 0.9822 1.4329 1.1696 0.1335  0.1134  -0.1341 462 ARG   A NH1 
538  N NH2 . ARG   A 89  ? 1.0737 1.5113 1.2368 0.1575  0.1206  -0.1790 462 ARG   A NH2 
539  N N   . ASP   A 90  ? 0.6417 0.7821 0.8077 0.1406  0.0095  -0.0653 463 ASP   A N   
540  C CA  . ASP   A 90  ? 0.6861 0.7988 0.8470 0.1325  -0.0057 -0.0469 463 ASP   A CA  
541  C C   . ASP   A 90  ? 0.6188 0.7692 0.7920 0.1121  -0.0026 -0.0321 463 ASP   A C   
542  O O   . ASP   A 90  ? 0.6298 0.7531 0.7862 0.0965  -0.0091 -0.0163 463 ASP   A O   
543  C CB  . ASP   A 90  ? 0.7530 0.8539 0.9322 0.1556  -0.0231 -0.0530 463 ASP   A CB  
544  C CG  . ASP   A 90  ? 0.7654 0.8083 0.9262 0.1719  -0.0318 -0.0600 463 ASP   A CG  
545  O OD1 . ASP   A 90  ? 0.8196 0.8229 0.9493 0.1609  -0.0268 -0.0564 463 ASP   A OD1 
546  O OD2 . ASP   A 90  ? 0.8187 0.8556 0.9970 0.1949  -0.0442 -0.0681 463 ASP   A OD2 
547  N N   . ARG   A 91  ? 0.5904 0.8033 0.7938 0.1122  0.0071  -0.0384 464 ARG   A N   
548  C CA  . ARG   A 91  ? 0.5970 0.8500 0.8193 0.0924  0.0093  -0.0252 464 ARG   A CA  
549  C C   . ARG   A 91  ? 0.5305 0.7807 0.7308 0.0664  0.0211  -0.0092 464 ARG   A C   
550  O O   . ARG   A 91  ? 0.4882 0.7534 0.6976 0.0465  0.0201  0.0054  464 ARG   A O   
551  C CB  . ARG   A 91  ? 0.6758 1.0017 0.9386 0.1005  0.0182  -0.0379 464 ARG   A CB  
552  C CG  . ARG   A 91  ? 0.8397 1.1912 1.1016 0.1141  0.0347  -0.0570 464 ARG   A CG  
553  C CD  . ARG   A 91  ? 0.9138 1.3482 1.2065 0.1110  0.0523  -0.0652 464 ARG   A CD  
554  N NE  . ARG   A 91  ? 1.0476 1.4999 1.3357 0.1288  0.0656  -0.0884 464 ARG   A NE  
555  C CZ  . ARG   A 91  ? 1.0755 1.5667 1.3527 0.1190  0.0861  -0.0916 464 ARG   A CZ  
556  N NH1 . ARG   A 91  ? 1.0716 1.5559 1.3329 0.1345  0.0935  -0.1125 464 ARG   A NH1 
557  N NH2 . ARG   A 91  ? 1.0469 1.5787 1.3256 0.0921  0.0981  -0.0724 464 ARG   A NH2 
558  N N   . LEU   A 92  ? 0.4659 0.6957 0.6383 0.0663  0.0308  -0.0118 465 LEU   A N   
559  C CA  . LEU   A 92  ? 0.4651 0.7000 0.6191 0.0453  0.0419  0.0025  465 LEU   A CA  
560  C C   . LEU   A 92  ? 0.4591 0.6367 0.5848 0.0348  0.0325  0.0163  465 LEU   A C   
561  O O   . LEU   A 92  ? 0.4660 0.5998 0.5730 0.0449  0.0255  0.0103  465 LEU   A O   
562  C CB  . LEU   A 92  ? 0.4780 0.7338 0.6191 0.0503  0.0576  -0.0085 465 LEU   A CB  
563  C CG  . LEU   A 92  ? 0.5103 0.8303 0.6774 0.0602  0.0701  -0.0245 465 LEU   A CG  
564  C CD1 . LEU   A 92  ? 0.5314 0.8667 0.6809 0.0677  0.0838  -0.0401 465 LEU   A CD1 
565  C CD2 . LEU   A 92  ? 0.5241 0.8962 0.7119 0.0405  0.0780  -0.0091 465 LEU   A CD2 
566  N N   . LEU   A 93  ? 0.4464 0.6259 0.5697 0.0140  0.0332  0.0348  466 LEU   A N   
567  C CA  . LEU   A 93  ? 0.4547 0.5860 0.5540 0.0041  0.0255  0.0469  466 LEU   A CA  
568  C C   . LEU   A 93  ? 0.4776 0.6145 0.5607 -0.0096 0.0356  0.0600  466 LEU   A C   
569  O O   . LEU   A 93  ? 0.4761 0.6488 0.5714 -0.0230 0.0433  0.0710  466 LEU   A O   
570  C CB  . LEU   A 93  ? 0.4460 0.5690 0.5599 -0.0062 0.0128  0.0557  466 LEU   A CB  
571  C CG  . LEU   A 93  ? 0.4744 0.5484 0.5679 -0.0144 0.0023  0.0643  466 LEU   A CG  
572  C CD1 . LEU   A 93  ? 0.4891 0.5223 0.5601 -0.0008 -0.0044 0.0553  466 LEU   A CD1 
573  C CD2 . LEU   A 93  ? 0.5116 0.5875 0.6242 -0.0257 -0.0095 0.0697  466 LEU   A CD2 
574  N N   . LEU   A 94  ? 0.4324 0.5362 0.4887 -0.0064 0.0351  0.0595  467 LEU   A N   
575  C CA  . LEU   A 94  ? 0.4562 0.5577 0.4951 -0.0171 0.0403  0.0732  467 LEU   A CA  
576  C C   . LEU   A 94  ? 0.5024 0.5686 0.5373 -0.0284 0.0294  0.0878  467 LEU   A C   
577  O O   . LEU   A 94  ? 0.4781 0.5093 0.5079 -0.0233 0.0191  0.0820  467 LEU   A O   
578  C CB  . LEU   A 94  ? 0.4610 0.5487 0.4764 -0.0073 0.0439  0.0632  467 LEU   A CB  
579  C CG  . LEU   A 94  ? 0.4916 0.6139 0.5068 0.0021  0.0553  0.0480  467 LEU   A CG  
580  C CD1 . LEU   A 94  ? 0.5097 0.6076 0.5068 0.0122  0.0543  0.0332  467 LEU   A CD1 
581  C CD2 . LEU   A 94  ? 0.5581 0.7196 0.5677 -0.0075 0.0663  0.0590  467 LEU   A CD2 
582  N N   . LEU   A 95  ? 0.5231 0.5974 0.5582 -0.0437 0.0317  0.1068  468 LEU   A N   
583  C CA  . LEU   A 95  ? 0.5006 0.5397 0.5332 -0.0545 0.0211  0.1204  468 LEU   A CA  
584  C C   . LEU   A 95  ? 0.5291 0.5578 0.5422 -0.0584 0.0232  0.1352  468 LEU   A C   
585  O O   . LEU   A 95  ? 0.5851 0.6447 0.5945 -0.0646 0.0329  0.1460  468 LEU   A O   
586  C CB  . LEU   A 95  ? 0.5125 0.5676 0.5698 -0.0712 0.0187  0.1309  468 LEU   A CB  
587  C CG  . LEU   A 95  ? 0.5235 0.5902 0.6026 -0.0667 0.0132  0.1168  468 LEU   A CG  
588  C CD1 . LEU   A 95  ? 0.5288 0.6191 0.6355 -0.0857 0.0114  0.1271  468 LEU   A CD1 
589  C CD2 . LEU   A 95  ? 0.5346 0.5575 0.6039 -0.0568 -0.0004 0.1055  468 LEU   A CD2 
590  N N   . GLY   A 96  ? 0.5254 0.5133 0.5250 -0.0532 0.0139  0.1344  469 GLY   A N   
591  C CA  . GLY   A 96  ? 0.5497 0.5239 0.5330 -0.0540 0.0123  0.1481  469 GLY   A CA  
592  C C   . GLY   A 96  ? 0.5504 0.4902 0.5392 -0.0645 0.0009  0.1633  469 GLY   A C   
593  O O   . GLY   A 96  ? 0.5455 0.4565 0.5409 -0.0632 -0.0086 0.1542  469 GLY   A O   
594  N N   . SER   A 97  ? 0.5716 0.5142 0.5564 -0.0752 0.0016  0.1865  470 SER   A N   
595  C CA  . SER   A 97  ? 0.5906 0.5011 0.5832 -0.0892 -0.0087 0.2047  470 SER   A CA  
596  C C   . SER   A 97  ? 0.6025 0.4728 0.5807 -0.0786 -0.0196 0.2097  470 SER   A C   
597  O O   . SER   A 97  ? 0.5743 0.4488 0.5378 -0.0624 -0.0180 0.2003  470 SER   A O   
598  C CB  . SER   A 97  ? 0.5996 0.5353 0.5968 -0.1097 -0.0017 0.2310  470 SER   A CB  
599  O OG  . SER   A 97  ? 0.5807 0.5232 0.5563 -0.1065 0.0011  0.2480  470 SER   A OG  
600  N N   . GLY   A 98  ? 0.6503 0.4828 0.6350 -0.0885 -0.0312 0.2246  471 GLY   A N   
601  C CA  . GLY   A 98  ? 0.6786 0.4715 0.6527 -0.0779 -0.0432 0.2320  471 GLY   A CA  
602  C C   . GLY   A 98  ? 0.7346 0.5283 0.6989 -0.0877 -0.0436 0.2650  471 GLY   A C   
603  O O   . GLY   A 98  ? 0.7602 0.5154 0.7190 -0.0816 -0.0564 0.2770  471 GLY   A O   
604  N N   . VAL   A 99  ? 0.7024 0.5413 0.6641 -0.1020 -0.0299 0.2790  472 VAL   A N   
605  C CA  . VAL   A 99  ? 0.7394 0.5881 0.6876 -0.1140 -0.0277 0.3123  472 VAL   A CA  
606  C C   . VAL   A 99  ? 0.7175 0.6237 0.6485 -0.1086 -0.0125 0.3104  472 VAL   A C   
607  O O   . VAL   A 99  ? 0.7269 0.6650 0.6503 -0.1243 -0.0031 0.3323  472 VAL   A O   
608  C CB  . VAL   A 99  ? 0.7694 0.6174 0.7317 -0.1440 -0.0256 0.3368  472 VAL   A CB  
609  C CG1 . VAL   A 99  ? 0.7907 0.5752 0.7676 -0.1515 -0.0433 0.3424  472 VAL   A CG1 
610  C CG2 . VAL   A 99  ? 0.7351 0.6320 0.7157 -0.1561 -0.0107 0.3227  472 VAL   A CG2 
611  N N   . GLY   A 100 ? 0.6874 0.6069 0.6119 -0.0877 -0.0100 0.2837  473 GLY   A N   
612  C CA  . GLY   A 100 ? 0.6743 0.6393 0.5799 -0.0796 0.0003  0.2797  473 GLY   A CA  
613  C C   . GLY   A 100 ? 0.6720 0.6905 0.5828 -0.0889 0.0182  0.2710  473 GLY   A C   
614  O O   . GLY   A 100 ? 0.6852 0.7457 0.5793 -0.0900 0.0281  0.2767  473 GLY   A O   
615  N N   . THR   A 101 ? 0.6417 0.6613 0.5753 -0.0935 0.0217  0.2550  474 THR   A N   
616  C CA  . THR   A 101 ? 0.6297 0.7004 0.5733 -0.1005 0.0374  0.2461  474 THR   A CA  
617  C C   . THR   A 101 ? 0.6217 0.6933 0.5782 -0.0861 0.0386  0.2131  474 THR   A C   
618  O O   . THR   A 101 ? 0.5931 0.6252 0.5568 -0.0793 0.0278  0.2025  474 THR   A O   
619  C CB  . THR   A 101 ? 0.6412 0.7223 0.6032 -0.1248 0.0410  0.2659  474 THR   A CB  
620  O OG1 . THR   A 101 ? 0.6258 0.6678 0.6092 -0.1280 0.0296  0.2592  474 THR   A OG1 
621  C CG2 . THR   A 101 ? 0.6437 0.7174 0.5917 -0.1419 0.0389  0.3027  474 THR   A CG2 
622  N N   . VAL   A 102 ? 0.6207 0.7376 0.5781 -0.0808 0.0517  0.1970  475 VAL   A N   
623  C CA  . VAL   A 102 ? 0.6015 0.7236 0.5736 -0.0692 0.0537  0.1691  475 VAL   A CA  
624  C C   . VAL   A 102 ? 0.5646 0.7308 0.5584 -0.0784 0.0644  0.1677  475 VAL   A C   
625  O O   . VAL   A 102 ? 0.5345 0.7470 0.5231 -0.0830 0.0774  0.1719  475 VAL   A O   
626  C CB  . VAL   A 102 ? 0.5978 0.7305 0.5542 -0.0518 0.0581  0.1471  475 VAL   A CB  
627  C CG1 . VAL   A 102 ? 0.5613 0.7003 0.5322 -0.0403 0.0608  0.1204  475 VAL   A CG1 
628  C CG2 . VAL   A 102 ? 0.6040 0.6990 0.5437 -0.0430 0.0478  0.1462  475 VAL   A CG2 
629  N N   . ARG   A 103 ? 0.5597 0.7154 0.5777 -0.0803 0.0587  0.1603  476 ARG   A N   
630  C CA  . ARG   A 103 ? 0.5909 0.7914 0.6349 -0.0871 0.0672  0.1562  476 ARG   A CA  
631  C C   . ARG   A 103 ? 0.5784 0.7911 0.6332 -0.0671 0.0686  0.1271  476 ARG   A C   
632  O O   . ARG   A 103 ? 0.5375 0.7114 0.5887 -0.0544 0.0580  0.1142  476 ARG   A O   
633  C CB  . ARG   A 103 ? 0.6403 0.8303 0.7091 -0.1041 0.0591  0.1675  476 ARG   A CB  
634  C CG  . ARG   A 103 ? 0.7430 0.8961 0.8026 -0.1216 0.0509  0.1937  476 ARG   A CG  
635  C CD  . ARG   A 103 ? 0.8566 1.0231 0.9413 -0.1466 0.0503  0.2102  476 ARG   A CD  
636  N NE  . ARG   A 103 ? 0.9018 1.0345 1.0049 -0.1484 0.0350  0.2015  476 ARG   A NE  
637  C CZ  . ARG   A 103 ? 0.9628 1.0481 1.0650 -0.1608 0.0219  0.2145  476 ARG   A CZ  
638  N NH1 . ARG   A 103 ? 1.0474 1.1101 1.1674 -0.1636 0.0086  0.2039  476 ARG   A NH1 
639  N NH2 . ARG   A 103 ? 0.9085 0.9694 0.9921 -0.1695 0.0211  0.2374  476 ARG   A NH2 
640  N N   . LEU   A 104 ? 0.5359 0.8038 0.6048 -0.0650 0.0816  0.1179  477 LEU   A N   
641  C CA  . LEU   A 104 ? 0.5046 0.7892 0.5915 -0.0468 0.0823  0.0921  477 LEU   A CA  
642  C C   . LEU   A 104 ? 0.5243 0.8342 0.6462 -0.0554 0.0800  0.0943  477 LEU   A C   
643  O O   . LEU   A 104 ? 0.5614 0.9210 0.6988 -0.0703 0.0912  0.1042  477 LEU   A O   
644  C CB  . LEU   A 104 ? 0.5051 0.8359 0.5859 -0.0361 0.0978  0.0766  477 LEU   A CB  
645  C CG  . LEU   A 104 ? 0.5041 0.8465 0.6003 -0.0126 0.0981  0.0464  477 LEU   A CG  
646  C CD1 . LEU   A 104 ? 0.4981 0.7813 0.5811 0.0028  0.0848  0.0340  477 LEU   A CD1 
647  C CD2 . LEU   A 104 ? 0.5068 0.8982 0.5965 -0.0041 0.1143  0.0304  477 LEU   A CD2 
648  N N   . TYR   A 105 ? 0.5189 0.7964 0.6524 -0.0475 0.0651  0.0861  478 TYR   A N   
649  C CA  . TYR   A 105 ? 0.5296 0.8273 0.6965 -0.0550 0.0588  0.0869  478 TYR   A CA  
650  C C   . TYR   A 105 ? 0.5022 0.8205 0.6898 -0.0317 0.0562  0.0627  478 TYR   A C   
651  O O   . TYR   A 105 ? 0.4598 0.7417 0.6337 -0.0124 0.0482  0.0494  478 TYR   A O   
652  C CB  . TYR   A 105 ? 0.5640 0.8089 0.7259 -0.0656 0.0418  0.0980  478 TYR   A CB  
653  C CG  . TYR   A 105 ? 0.6129 0.8721 0.8074 -0.0746 0.0314  0.0977  478 TYR   A CG  
654  C CD1 . TYR   A 105 ? 0.6629 0.9558 0.8803 -0.0997 0.0358  0.1127  478 TYR   A CD1 
655  C CD2 . TYR   A 105 ? 0.6406 0.8795 0.8419 -0.0598 0.0161  0.0836  478 TYR   A CD2 
656  C CE1 . TYR   A 105 ? 0.6492 0.9577 0.8986 -0.1097 0.0252  0.1110  478 TYR   A CE1 
657  C CE2 . TYR   A 105 ? 0.6293 0.8838 0.8599 -0.0676 0.0046  0.0824  478 TYR   A CE2 
658  C CZ  . TYR   A 105 ? 0.6292 0.9199 0.8854 -0.0926 0.0090  0.0947  478 TYR   A CZ  
659  O OH  . TYR   A 105 ? 0.6342 0.9438 0.9216 -0.1020 -0.0029 0.0920  478 TYR   A OH  
660  N N   . ASP   A 106 ? 0.5266 0.9042 0.7484 -0.0340 0.0625  0.0578  479 ASP   A N   
661  C CA  . ASP   A 106 ? 0.5039 0.9061 0.7507 -0.0102 0.0588  0.0351  479 ASP   A CA  
662  C C   . ASP   A 106 ? 0.4906 0.8872 0.7629 -0.0133 0.0411  0.0368  479 ASP   A C   
663  O O   . ASP   A 106 ? 0.4784 0.9124 0.7771 -0.0332 0.0425  0.0464  479 ASP   A O   
664  C CB  . ASP   A 106 ? 0.5017 0.9770 0.7696 -0.0053 0.0774  0.0235  479 ASP   A CB  
665  C CG  . ASP   A 106 ? 0.5083 1.0203 0.8113 0.0194  0.0737  -0.0003 479 ASP   A CG  
666  O OD1 . ASP   A 106 ? 0.4770 0.9644 0.7933 0.0286  0.0551  -0.0035 479 ASP   A OD1 
667  O OD2 . ASP   A 106 ? 0.5162 1.0822 0.8325 0.0303  0.0890  -0.0160 479 ASP   A OD2 
668  N N   . THR   A 107 ? 0.4927 0.8454 0.7569 0.0058  0.0244  0.0271  480 THR   A N   
669  C CA  . THR   A 107 ? 0.5138 0.8478 0.7901 0.0025  0.0045  0.0303  480 THR   A CA  
670  C C   . THR   A 107 ? 0.5201 0.9097 0.8408 0.0121  -0.0008 0.0187  480 THR   A C   
671  O O   . THR   A 107 ? 0.5487 0.9427 0.8877 0.0026  -0.0151 0.0228  480 THR   A O   
672  C CB  . THR   A 107 ? 0.5175 0.7852 0.7641 0.0172  -0.0111 0.0272  480 THR   A CB  
673  O OG1 . THR   A 107 ? 0.5300 0.7960 0.7776 0.0453  -0.0126 0.0108  480 THR   A OG1 
674  C CG2 . THR   A 107 ? 0.5160 0.7338 0.7231 0.0071  -0.0065 0.0376  480 THR   A CG2 
675  N N   . GLU   A 108 ? 0.5637 0.9981 0.9032 0.0313  0.0098  0.0027  481 GLU   A N   
676  C CA  . GLU   A 108 ? 0.6064 1.1027 0.9933 0.0413  0.0057  -0.0093 481 GLU   A CA  
677  C C   . GLU   A 108 ? 0.6016 1.1676 1.0180 0.0151  0.0219  -0.0016 481 GLU   A C   
678  O O   . GLU   A 108 ? 0.6706 1.2765 1.1235 0.0055  0.0142  -0.0009 481 GLU   A O   
679  C CB  . GLU   A 108 ? 0.7099 1.2248 1.1123 0.0777  0.0049  -0.0330 481 GLU   A CB  
680  C CG  . GLU   A 108 ? 0.8030 1.3070 1.1814 0.0914  0.0213  -0.0441 481 GLU   A CG  
681  C CD  . GLU   A 108 ? 0.8788 1.4196 1.2839 0.1252  0.0239  -0.0711 481 GLU   A CD  
682  O OE1 . GLU   A 108 ? 0.8482 1.4291 1.2937 0.1385  0.0136  -0.0802 481 GLU   A OE1 
683  O OE2 . GLU   A 108 ? 0.8533 1.3847 1.2409 0.1389  0.0353  -0.0848 481 GLU   A OE2 
684  N N   . ALA   A 109 ? 0.6000 1.1814 0.9999 0.0016  0.0436  0.0053  482 ALA   A N   
685  C CA  . ALA   A 109 ? 0.5984 1.2458 1.0223 -0.0259 0.0608  0.0162  482 ALA   A CA  
686  C C   . ALA   A 109 ? 0.6028 1.2221 1.0205 -0.0616 0.0539  0.0418  482 ALA   A C   
687  O O   . ALA   A 109 ? 0.6068 1.2753 1.0525 -0.0882 0.0611  0.0527  482 ALA   A O   
688  C CB  . ALA   A 109 ? 0.5907 1.2653 0.9955 -0.0271 0.0854  0.0157  482 ALA   A CB  
689  N N   . LYS   A 110 ? 0.6278 1.1681 1.0102 -0.0621 0.0396  0.0503  483 LYS   A N   
690  C CA  . LYS   A 110 ? 0.6755 1.1782 1.0499 -0.0912 0.0300  0.0705  483 LYS   A CA  
691  C C   . LYS   A 110 ? 0.6825 1.1967 1.0447 -0.1195 0.0480  0.0926  483 LYS   A C   
692  O O   . LYS   A 110 ? 0.6903 1.2196 1.0705 -0.1499 0.0482  0.1087  483 LYS   A O   
693  C CB  . LYS   A 110 ? 0.6756 1.2049 1.0904 -0.1025 0.0147  0.0679  483 LYS   A CB  
694  C CG  . LYS   A 110 ? 0.6645 1.1663 1.0824 -0.0779 -0.0092 0.0518  483 LYS   A CG  
695  C CD  . LYS   A 110 ? 0.6543 1.2192 1.1215 -0.0681 -0.0181 0.0369  483 LYS   A CD  
696  C CE  . LYS   A 110 ? 0.6494 1.2119 1.1376 -0.0850 -0.0396 0.0390  483 LYS   A CE  
697  N N   . LYS   A 111 ? 0.6883 1.1925 1.0184 -0.1101 0.0620  0.0940  484 LYS   A N   
698  C CA  . LYS   A 111 ? 0.7270 1.2463 1.0416 -0.1337 0.0791  0.1157  484 LYS   A CA  
699  C C   . LYS   A 111 ? 0.7127 1.1918 0.9817 -0.1202 0.0845  0.1170  484 LYS   A C   
700  O O   . LYS   A 111 ? 0.5906 1.0595 0.8482 -0.0919 0.0836  0.0963  484 LYS   A O   
701  C CB  . LYS   A 111 ? 0.7404 1.3493 1.0841 -0.1432 0.1001  0.1144  484 LYS   A CB  
702  C CG  . LYS   A 111 ? 0.7357 1.3890 1.0797 -0.1139 0.1139  0.0897  484 LYS   A CG  
703  N N   . ASN   A 112 ? 0.7081 1.1641 0.9524 -0.1416 0.0889  0.1421  485 ASN   A N   
704  C CA  . ASN   A 112 ? 0.6866 1.1140 0.8896 -0.1328 0.0943  0.1468  485 ASN   A CA  
705  C C   . ASN   A 112 ? 0.6329 1.1250 0.8327 -0.1272 0.1159  0.1398  485 ASN   A C   
706  O O   . ASN   A 112 ? 0.6662 1.2115 0.8785 -0.1478 0.1301  0.1535  485 ASN   A O   
707  C CB  . ASN   A 112 ? 0.7053 1.0890 0.8853 -0.1555 0.0899  0.1766  485 ASN   A CB  
708  C CG  . ASN   A 112 ? 0.7670 1.0810 0.9440 -0.1562 0.0684  0.1786  485 ASN   A CG  
709  O OD1 . ASN   A 112 ? 0.7372 1.0113 0.9002 -0.1343 0.0582  0.1622  485 ASN   A OD1 
710  N ND2 . ASN   A 112 ? 0.8019 1.1000 0.9912 -0.1823 0.0615  0.1982  485 ASN   A ND2 
711  N N   . LEU   A 113 ? 0.6284 1.1158 0.8109 -0.1002 0.1185  0.1177  486 LEU   A N   
712  C CA  . LEU   A 113 ? 0.6067 1.1537 0.7850 -0.0910 0.1378  0.1045  486 LEU   A CA  
713  C C   . LEU   A 113 ? 0.6242 1.1708 0.7649 -0.1044 0.1474  0.1252  486 LEU   A C   
714  O O   . LEU   A 113 ? 0.6250 1.2319 0.7626 -0.1127 0.1657  0.1289  486 LEU   A O   
715  C CB  . LEU   A 113 ? 0.6051 1.1426 0.7802 -0.0576 0.1350  0.0712  486 LEU   A CB  
716  C CG  . LEU   A 113 ? 0.6057 1.1579 0.8187 -0.0394 0.1278  0.0483  486 LEU   A CG  
717  C CD1 . LEU   A 113 ? 0.5841 1.1186 0.7890 -0.0072 0.1248  0.0181  486 LEU   A CD1 
718  C CD2 . LEU   A 113 ? 0.5987 1.2329 0.8490 -0.0475 0.1418  0.0451  486 LEU   A CD2 
719  N N   . CYS   A 114 ? 0.6150 1.0963 0.7263 -0.1039 0.1348  0.1368  487 CYS   A N   
720  C CA  . CYS   A 114 ? 0.6033 1.0788 0.6793 -0.1155 0.1398  0.1591  487 CYS   A CA  
721  C C   . CYS   A 114 ? 0.5886 0.9886 0.6463 -0.1189 0.1216  0.1758  487 CYS   A C   
722  O O   . CYS   A 114 ? 0.5532 0.9085 0.6210 -0.1087 0.1072  0.1644  487 CYS   A O   
723  C CB  . CYS   A 114 ? 0.6296 1.1339 0.6815 -0.0978 0.1508  0.1399  487 CYS   A CB  
724  S SG  . CYS   A 114 ? 0.6243 1.0773 0.6655 -0.0666 0.1379  0.1078  487 CYS   A SG  
725  N N   . GLU   A 115 ? 0.5866 0.9762 0.6180 -0.1334 0.1223  0.2036  488 GLU   A N   
726  C CA  . GLU   A 115 ? 0.6332 0.9561 0.6464 -0.1352 0.1058  0.2203  488 GLU   A CA  
727  C C   . GLU   A 115 ? 0.6366 0.9623 0.6122 -0.1332 0.1088  0.2337  488 GLU   A C   
728  O O   . GLU   A 115 ? 0.6433 1.0068 0.6064 -0.1489 0.1199  0.2552  488 GLU   A O   
729  C CB  . GLU   A 115 ? 0.6950 0.9930 0.7244 -0.1598 0.0981  0.2467  488 GLU   A CB  
730  C CG  . GLU   A 115 ? 0.7745 1.0057 0.7849 -0.1622 0.0815  0.2662  488 GLU   A CG  
731  C CD  . GLU   A 115 ? 0.7994 0.9817 0.8305 -0.1738 0.0662  0.2732  488 GLU   A CD  
732  O OE1 . GLU   A 115 ? 0.8145 1.0160 0.8708 -0.1950 0.0692  0.2826  488 GLU   A OE1 
733  O OE2 . GLU   A 115 ? 0.8224 0.9489 0.8447 -0.1615 0.0511  0.2678  488 GLU   A OE2 
734  N N   . ILE   A 116 ? 0.6330 0.9250 0.5906 -0.1136 0.0997  0.2196  489 ILE   A N   
735  C CA  . ILE   A 116 ? 0.6731 0.9759 0.5972 -0.1077 0.1018  0.2251  489 ILE   A CA  
736  C C   . ILE   A 116 ? 0.6950 0.9404 0.6036 -0.1066 0.0846  0.2437  489 ILE   A C   
737  O O   . ILE   A 116 ? 0.6672 0.8660 0.5848 -0.0961 0.0721  0.2318  489 ILE   A O   
738  C CB  . ILE   A 116 ? 0.7169 1.0405 0.6335 -0.0859 0.1070  0.1902  489 ILE   A CB  
739  C CG1 . ILE   A 116 ? 0.7981 1.1834 0.7280 -0.0851 0.1245  0.1721  489 ILE   A CG1 
740  C CG2 . ILE   A 116 ? 0.7769 1.1046 0.6589 -0.0792 0.1047  0.1942  489 ILE   A CG2 
741  C CD1 . ILE   A 116 ? 0.8766 1.2568 0.8405 -0.0768 0.1236  0.1492  489 ILE   A CD1 
742  N N   . ASN   A 117 ? 0.7434 0.9955 0.6283 -0.1172 0.0844  0.2734  490 ASN   A N   
743  C CA  . ASN   A 117 ? 0.8342 1.0374 0.7028 -0.1147 0.0677  0.2942  490 ASN   A CA  
744  C C   . ASN   A 117 ? 0.8957 1.0989 0.7440 -0.0928 0.0626  0.2753  490 ASN   A C   
745  O O   . ASN   A 117 ? 0.9251 1.1749 0.7558 -0.0885 0.0727  0.2658  490 ASN   A O   
746  C CB  . ASN   A 117 ? 0.9271 1.1372 0.7781 -0.1347 0.0684  0.3358  490 ASN   A CB  
747  C CG  . ASN   A 117 ? 1.0016 1.1492 0.8614 -0.1443 0.0520  0.3612  490 ASN   A CG  
748  O OD1 . ASN   A 117 ? 0.9929 1.0944 0.8449 -0.1299 0.0355  0.3624  490 ASN   A OD1 
749  N ND2 . ASN   A 117 ? 0.9684 1.1148 0.8465 -0.1684 0.0561  0.3793  490 ASN   A ND2 
750  N N   . ILE   A 118 ? 0.8779 1.0317 0.7309 -0.0796 0.0475  0.2670  491 ILE   A N   
751  C CA  . ILE   A 118 ? 0.9471 1.0934 0.7819 -0.0624 0.0384  0.2587  491 ILE   A CA  
752  C C   . ILE   A 118 ? 1.2278 1.3678 1.0394 -0.0665 0.0291  0.2935  491 ILE   A C   
753  O O   . ILE   A 118 ? 1.2333 1.3269 1.0496 -0.0684 0.0155  0.3141  491 ILE   A O   
754  C CB  . ILE   A 118 ? 0.9533 1.0532 0.8037 -0.0489 0.0268  0.2397  491 ILE   A CB  
755  C CG1 . ILE   A 118 ? 0.9286 1.0409 0.7915 -0.0408 0.0350  0.2044  491 ILE   A CG1 
756  C CG2 . ILE   A 118 ? 0.9802 1.0603 0.8173 -0.0346 0.0125  0.2430  491 ILE   A CG2 
757  C CD1 . ILE   A 118 ? 0.9373 1.0465 0.8235 -0.0496 0.0413  0.1985  491 ILE   A CD1 
758  N N   . ASN   A 119 ? 1.3313 1.5181 1.1169 -0.0677 0.0360  0.3001  492 ASN   A N   
759  C CA  . ASN   A 119 ? 1.4828 1.6700 1.2414 -0.0719 0.0273  0.3358  492 ASN   A CA  
760  C C   . ASN   A 119 ? 1.5317 1.6841 1.2855 -0.0522 0.0073  0.3344  492 ASN   A C   
761  O O   . ASN   A 119 ? 1.4717 1.6516 1.2069 -0.0399 0.0039  0.3246  492 ASN   A O   
762  C CB  . ASN   A 119 ? 1.4548 1.7060 1.1842 -0.0773 0.0398  0.3404  492 ASN   A CB  
763  C CG  . ASN   A 119 ? 1.4617 1.7511 1.1953 -0.0983 0.0595  0.3487  492 ASN   A CG  
764  O OD1 . ASN   A 119 ? 1.5363 1.8023 1.2848 -0.1154 0.0602  0.3717  492 ASN   A OD1 
765  N ND2 . ASN   A 119 ? 1.3721 1.7225 1.0940 -0.0977 0.0757  0.3290  492 ASN   A ND2 
766  N N   . ASP   A 120 ? 1.4799 1.5745 1.2520 -0.0493 -0.0059 0.3425  493 ASP   A N   
767  C CA  . ASP   A 120 ? 1.3500 1.4114 1.1258 -0.0286 -0.0238 0.3347  493 ASP   A CA  
768  C C   . ASP   A 120 ? 1.2899 1.2884 1.0805 -0.0293 -0.0386 0.3540  493 ASP   A C   
769  O O   . ASP   A 120 ? 1.3325 1.3112 1.1306 -0.0478 -0.0356 0.3736  493 ASP   A O   
770  C CB  . ASP   A 120 ? 1.3731 1.4418 1.1648 -0.0152 -0.0196 0.2922  493 ASP   A CB  
771  C CG  . ASP   A 120 ? 1.3465 1.4535 1.1235 -0.0016 -0.0205 0.2731  493 ASP   A CG  
772  O OD1 . ASP   A 120 ? 1.3868 1.5143 1.1403 0.0014  -0.0278 0.2924  493 ASP   A OD1 
773  O OD2 . ASP   A 120 ? 1.1052 1.2206 0.8942 0.0049  -0.0150 0.2397  493 ASP   A OD2 
774  N N   . ASN   A 121 ? 1.2193 1.1886 1.0164 -0.0086 -0.0545 0.3450  494 ASN   A N   
775  C CA  . ASN   A 121 ? 1.2236 1.1321 1.0346 -0.0028 -0.0713 0.3574  494 ASN   A CA  
776  C C   . ASN   A 121 ? 1.0861 0.9702 0.9236 0.0055  -0.0707 0.3233  494 ASN   A C   
777  O O   . ASN   A 121 ? 1.0281 0.8690 0.8781 0.0187  -0.0852 0.3204  494 ASN   A O   
778  C CB  . ASN   A 121 ? 1.3710 1.2691 1.1698 0.0175  -0.0907 0.3716  494 ASN   A CB  
779  C CG  . ASN   A 121 ? 1.4149 1.3601 1.2069 0.0341  -0.0888 0.3460  494 ASN   A CG  
780  O OD1 . ASN   A 121 ? 1.3316 1.3076 1.1299 0.0310  -0.0738 0.3157  494 ASN   A OD1 
781  N ND2 . ASN   A 121 ? 1.4273 1.3786 1.2069 0.0513  -0.1049 0.3578  494 ASN   A ND2 
782  N N   . MET   A 122 ? 0.9260 0.8389 0.7708 -0.0009 -0.0542 0.2972  495 MET   A N   
783  C CA  . MET   A 122 ? 0.8191 0.7172 0.6836 0.0065  -0.0522 0.2650  495 MET   A CA  
784  C C   . MET   A 122 ? 0.7486 0.6412 0.6262 -0.0113 -0.0417 0.2609  495 MET   A C   
785  O O   . MET   A 122 ? 0.6883 0.6158 0.5657 -0.0177 -0.0274 0.2470  495 MET   A O   
786  C CB  . MET   A 122 ? 0.7915 0.7287 0.6528 0.0163  -0.0435 0.2358  495 MET   A CB  
787  C CG  . MET   A 122 ? 0.8205 0.7828 0.6671 0.0299  -0.0507 0.2387  495 MET   A CG  
788  S SD  . MET   A 122 ? 0.8140 0.7645 0.6745 0.0528  -0.0614 0.2136  495 MET   A SD  
789  C CE  . MET   A 122 ? 0.8176 0.7946 0.6639 0.0695  -0.0755 0.2251  495 MET   A CE  
790  N N   . PRO   A 123 ? 0.7657 0.6159 0.6556 -0.0200 -0.0496 0.2733  496 PRO   A N   
791  C CA  . PRO   A 123 ? 0.7469 0.5967 0.6503 -0.0394 -0.0412 0.2732  496 PRO   A CA  
792  C C   . PRO   A 123 ? 0.7034 0.5483 0.6227 -0.0363 -0.0373 0.2424  496 PRO   A C   
793  O O   . PRO   A 123 ? 0.7197 0.5699 0.6511 -0.0509 -0.0313 0.2409  496 PRO   A O   
794  C CB  . PRO   A 123 ? 0.7981 0.5999 0.7077 -0.0503 -0.0545 0.2996  496 PRO   A CB  
795  C CG  . PRO   A 123 ? 0.8178 0.5810 0.7267 -0.0283 -0.0713 0.2948  496 PRO   A CG  
796  C CD  . PRO   A 123 ? 0.8188 0.6206 0.7103 -0.0124 -0.0679 0.2901  496 PRO   A CD  
797  N N   . ARG   A 124 ? 0.6649 0.5004 0.5846 -0.0180 -0.0415 0.2192  497 ARG   A N   
798  C CA  . ARG   A 124 ? 0.6384 0.4632 0.5700 -0.0157 -0.0398 0.1935  497 ARG   A CA  
799  C C   . ARG   A 124 ? 0.5867 0.4494 0.5140 -0.0126 -0.0265 0.1738  497 ARG   A C   
800  O O   . ARG   A 124 ? 0.5654 0.4400 0.4853 0.0000  -0.0251 0.1602  497 ARG   A O   
801  C CB  . ARG   A 124 ? 0.6482 0.4373 0.5837 -0.0001 -0.0519 0.1804  497 ARG   A CB  
802  C CG  . ARG   A 124 ? 0.7317 0.4756 0.6748 -0.0042 -0.0661 0.1966  497 ARG   A CG  
803  C CD  . ARG   A 124 ? 0.7139 0.4215 0.6652 0.0096  -0.0770 0.1764  497 ARG   A CD  
804  N NE  . ARG   A 124 ? 0.7375 0.4546 0.6832 0.0314  -0.0792 0.1645  497 ARG   A NE  
805  C CZ  . ARG   A 124 ? 0.6926 0.4186 0.6395 0.0443  -0.0760 0.1371  497 ARG   A CZ  
806  N NH1 . ARG   A 124 ? 0.6883 0.4070 0.6392 0.0399  -0.0728 0.1183  497 ARG   A NH1 
807  N NH2 . ARG   A 124 ? 0.6995 0.4425 0.6436 0.0612  -0.0770 0.1294  497 ARG   A NH2 
808  N N   . ILE   A 125 ? 0.5740 0.4547 0.5084 -0.0243 -0.0177 0.1714  498 ILE   A N   
809  C CA  . ILE   A 125 ? 0.5518 0.4606 0.4847 -0.0207 -0.0069 0.1519  498 ILE   A CA  
810  C C   . ILE   A 125 ? 0.5266 0.4136 0.4651 -0.0147 -0.0102 0.1313  498 ILE   A C   
811  O O   . ILE   A 125 ? 0.5028 0.3848 0.4516 -0.0211 -0.0104 0.1268  498 ILE   A O   
812  C CB  . ILE   A 125 ? 0.5518 0.4924 0.4912 -0.0324 0.0033  0.1568  498 ILE   A CB  
813  C CG1 . ILE   A 125 ? 0.5688 0.5296 0.5019 -0.0424 0.0066  0.1812  498 ILE   A CG1 
814  C CG2 . ILE   A 125 ? 0.5506 0.5189 0.4872 -0.0254 0.0134  0.1363  498 ILE   A CG2 
815  C CD1 . ILE   A 125 ? 0.5785 0.5562 0.4920 -0.0336 0.0076  0.1848  498 ILE   A CD1 
816  N N   . LEU   A 126 ? 0.5423 0.4216 0.4734 -0.0026 -0.0125 0.1186  499 LEU   A N   
817  C CA  . LEU   A 126 ? 0.5499 0.4090 0.4824 0.0028  -0.0156 0.1010  499 LEU   A CA  
818  C C   . LEU   A 126 ? 0.5475 0.4196 0.4782 0.0020  -0.0076 0.0863  499 LEU   A C   
819  O O   . LEU   A 126 ? 0.5512 0.4077 0.4831 0.0020  -0.0102 0.0767  499 LEU   A O   
820  C CB  . LEU   A 126 ? 0.5458 0.3971 0.4729 0.0152  -0.0199 0.0931  499 LEU   A CB  
821  C CG  . LEU   A 126 ? 0.5958 0.4232 0.5268 0.0201  -0.0316 0.1048  499 LEU   A CG  
822  C CD1 . LEU   A 126 ? 0.6020 0.4291 0.5311 0.0356  -0.0356 0.0941  499 LEU   A CD1 
823  C CD2 . LEU   A 126 ? 0.6116 0.4058 0.5515 0.0145  -0.0398 0.1054  499 LEU   A CD2 
824  N N   . SER   A 127 ? 0.5449 0.4441 0.4723 0.0013  0.0010  0.0847  500 SER   A N   
825  C CA  . SER   A 127 ? 0.4819 0.3872 0.4072 0.0027  0.0071  0.0697  500 SER   A CA  
826  C C   . SER   A 127 ? 0.4716 0.4051 0.3992 0.0005  0.0152  0.0699  500 SER   A C   
827  O O   . SER   A 127 ? 0.4634 0.4181 0.3875 -0.0003 0.0184  0.0773  500 SER   A O   
828  C CB  . SER   A 127 ? 0.4885 0.3920 0.4046 0.0083  0.0089  0.0573  500 SER   A CB  
829  O OG  . SER   A 127 ? 0.5195 0.4182 0.4322 0.0079  0.0128  0.0448  500 SER   A OG  
830  N N   . LEU   A 128 ? 0.4592 0.3936 0.3927 0.0005  0.0177  0.0621  501 LEU   A N   
831  C CA  . LEU   A 128 ? 0.4405 0.4009 0.3784 0.0017  0.0253  0.0567  501 LEU   A CA  
832  C C   . LEU   A 128 ? 0.4774 0.4265 0.4130 0.0073  0.0266  0.0405  501 LEU   A C   
833  O O   . LEU   A 128 ? 0.5059 0.4315 0.4421 0.0080  0.0210  0.0388  501 LEU   A O   
834  C CB  . LEU   A 128 ? 0.4559 0.4298 0.4094 -0.0029 0.0254  0.0649  501 LEU   A CB  
835  C CG  . LEU   A 128 ? 0.4962 0.4868 0.4525 -0.0116 0.0267  0.0829  501 LEU   A CG  
836  C CD1 . LEU   A 128 ? 0.5163 0.5096 0.4900 -0.0197 0.0236  0.0917  501 LEU   A CD1 
837  C CD2 . LEU   A 128 ? 0.5380 0.5662 0.4892 -0.0112 0.0370  0.0824  501 LEU   A CD2 
838  N N   . ALA   A 129 ? 0.4635 0.4276 0.3951 0.0107  0.0330  0.0290  502 ALA   A N   
839  C CA  . ALA   A 129 ? 0.4615 0.4119 0.3925 0.0154  0.0338  0.0143  502 ALA   A CA  
840  C C   . ALA   A 129 ? 0.4672 0.4427 0.4046 0.0207  0.0403  0.0030  502 ALA   A C   
841  O O   . ALA   A 129 ? 0.4740 0.4742 0.4058 0.0200  0.0459  -0.0012 502 ALA   A O   
842  C CB  . ALA   A 129 ? 0.4585 0.3915 0.3771 0.0131  0.0336  0.0070  502 ALA   A CB  
843  N N   . CYS   A 130 ? 0.4476 0.4168 0.3960 0.0275  0.0386  -0.0033 503 CYS   A N   
844  C CA  . CYS   A 130 ? 0.4621 0.4537 0.4199 0.0359  0.0442  -0.0180 503 CYS   A CA  
845  C C   . CYS   A 130 ? 0.4688 0.4356 0.4206 0.0410  0.0432  -0.0356 503 CYS   A C   
846  O O   . CYS   A 130 ? 0.5020 0.4325 0.4502 0.0410  0.0367  -0.0342 503 CYS   A O   
847  C CB  . CYS   A 130 ? 0.4788 0.4819 0.4562 0.0419  0.0418  -0.0150 503 CYS   A CB  
848  S SG  . CYS   A 130 ? 0.5019 0.5388 0.4959 0.0558  0.0489  -0.0353 503 CYS   A SG  
849  N N   A SER   A 131 ? 0.4758 0.4620 0.4248 0.0435  0.0496  -0.0516 504 SER   A N   
850  N N   B SER   A 131 ? 0.4538 0.4403 0.4031 0.0438  0.0496  -0.0519 504 SER   A N   
851  C CA  A SER   A 131 ? 0.4860 0.4483 0.4312 0.0467  0.0484  -0.0705 504 SER   A CA  
852  C CA  B SER   A 131 ? 0.4499 0.4127 0.3950 0.0468  0.0486  -0.0709 504 SER   A CA  
853  C C   A SER   A 131 ? 0.4918 0.4289 0.4496 0.0586  0.0427  -0.0768 504 SER   A C   
854  C C   B SER   A 131 ? 0.4748 0.4128 0.4327 0.0589  0.0430  -0.0780 504 SER   A C   
855  O O   A SER   A 131 ? 0.4878 0.4460 0.4613 0.0684  0.0431  -0.0765 504 SER   A O   
856  O O   B SER   A 131 ? 0.4764 0.4367 0.4502 0.0693  0.0439  -0.0795 504 SER   A O   
857  C CB  A SER   A 131 ? 0.5101 0.5025 0.4520 0.0488  0.0555  -0.0897 504 SER   A CB  
858  C CB  B SER   A 131 ? 0.4463 0.4398 0.3874 0.0483  0.0557  -0.0902 504 SER   A CB  
859  O OG  A SER   A 131 ? 0.5342 0.4997 0.4699 0.0464  0.0533  -0.1068 504 SER   A OG  
860  O OG  B SER   A 131 ? 0.4176 0.4390 0.3714 0.0608  0.0606  -0.1041 504 SER   A OG  
861  N N   . PRO   A 132 ? 0.4874 0.3801 0.4394 0.0578  0.0368  -0.0820 505 PRO   A N   
862  C CA  . PRO   A 132 ? 0.5318 0.3950 0.4942 0.0711  0.0293  -0.0884 505 PRO   A CA  
863  C C   . PRO   A 132 ? 0.5487 0.4349 0.5282 0.0881  0.0322  -0.1102 505 PRO   A C   
864  O O   . PRO   A 132 ? 0.6205 0.5002 0.6155 0.1032  0.0262  -0.1122 505 PRO   A O   
865  C CB  . PRO   A 132 ? 0.5548 0.3684 0.5041 0.0628  0.0249  -0.0922 505 PRO   A CB  
866  C CG  . PRO   A 132 ? 0.5687 0.3863 0.5020 0.0442  0.0285  -0.0789 505 PRO   A CG  
867  C CD  . PRO   A 132 ? 0.5011 0.3699 0.4369 0.0433  0.0363  -0.0788 505 PRO   A CD  
868  N N   . ASN   A 133 ? 0.5495 0.4620 0.5259 0.0868  0.0406  -0.1285 506 ASN   A N   
869  C CA  . ASN   A 133 ? 0.5674 0.5026 0.5582 0.1037  0.0443  -0.1540 506 ASN   A CA  
870  C C   . ASN   A 133 ? 0.5289 0.5243 0.5312 0.1086  0.0530  -0.1502 506 ASN   A C   
871  O O   . ASN   A 133 ? 0.5568 0.5808 0.5743 0.1238  0.0574  -0.1696 506 ASN   A O   
872  C CB  . ASN   A 133 ? 0.5984 0.5322 0.5802 0.1010  0.0481  -0.1795 506 ASN   A CB  
873  C CG  . ASN   A 133 ? 0.6311 0.6133 0.5998 0.0900  0.0580  -0.1805 506 ASN   A CG  
874  O OD1 . ASN   A 133 ? 0.5876 0.6023 0.5529 0.0832  0.0625  -0.1600 506 ASN   A OD1 
875  N ND2 . ASN   A 133 ? 0.6742 0.6610 0.6351 0.0882  0.0603  -0.2048 506 ASN   A ND2 
876  N N   . GLY   A 134 ? 0.4970 0.5113 0.4931 0.0953  0.0554  -0.1256 507 GLY   A N   
877  C CA  . GLY   A 134 ? 0.4890 0.5529 0.4987 0.0971  0.0619  -0.1166 507 GLY   A CA  
878  C C   . GLY   A 134 ? 0.5057 0.6238 0.5078 0.0922  0.0750  -0.1228 507 GLY   A C   
879  O O   . GLY   A 134 ? 0.4716 0.6348 0.4831 0.0905  0.0823  -0.1142 507 GLY   A O   
880  N N   . ALA   A 135 ? 0.5333 0.6483 0.5176 0.0885  0.0775  -0.1369 508 ALA   A N   
881  C CA  . ALA   A 135 ? 0.5649 0.7312 0.5382 0.0855  0.0885  -0.1456 508 ALA   A CA  
882  C C   . ALA   A 135 ? 0.5429 0.7212 0.4977 0.0681  0.0897  -0.1193 508 ALA   A C   
883  O O   . ALA   A 135 ? 0.5542 0.7784 0.4987 0.0635  0.0981  -0.1161 508 ALA   A O   
884  C CB  . ALA   A 135 ? 0.5742 0.7340 0.5382 0.0911  0.0890  -0.1768 508 ALA   A CB  
885  N N   . SER   A 136 ? 0.5475 0.6856 0.4976 0.0592  0.0809  -0.1002 509 SER   A N   
886  C CA  . SER   A 136 ? 0.5298 0.6740 0.4635 0.0459  0.0799  -0.0787 509 SER   A CA  
887  C C   . SER   A 136 ? 0.5118 0.6230 0.4502 0.0396  0.0722  -0.0551 509 SER   A C   
888  O O   . SER   A 136 ? 0.5044 0.5845 0.4542 0.0443  0.0667  -0.0566 509 SER   A O   
889  C CB  . SER   A 136 ? 0.5300 0.6676 0.4462 0.0415  0.0776  -0.0898 509 SER   A CB  
890  O OG  . SER   A 136 ? 0.5709 0.6613 0.4888 0.0402  0.0700  -0.0957 509 SER   A OG  
891  N N   . PHE   A 137 ? 0.4784 0.5982 0.4073 0.0299  0.0713  -0.0333 510 PHE   A N   
892  C CA  . PHE   A 137 ? 0.4645 0.5515 0.3944 0.0240  0.0633  -0.0146 510 PHE   A CA  
893  C C   . PHE   A 137 ? 0.4647 0.5551 0.3793 0.0170  0.0606  -0.0012 510 PHE   A C   
894  O O   . PHE   A 137 ? 0.5261 0.6478 0.4295 0.0153  0.0646  0.0002  510 PHE   A O   
895  C CB  . PHE   A 137 ? 0.4628 0.5524 0.4081 0.0218  0.0622  0.0011  510 PHE   A CB  
896  C CG  . PHE   A 137 ? 0.4545 0.5766 0.3989 0.0131  0.0668  0.0205  510 PHE   A CG  
897  C CD1 . PHE   A 137 ? 0.4408 0.6078 0.3905 0.0136  0.0770  0.0170  510 PHE   A CD1 
898  C CD2 . PHE   A 137 ? 0.4402 0.5476 0.3780 0.0044  0.0610  0.0421  510 PHE   A CD2 
899  C CE1 . PHE   A 137 ? 0.4445 0.6411 0.3911 0.0027  0.0820  0.0377  510 PHE   A CE1 
900  C CE2 . PHE   A 137 ? 0.4222 0.5539 0.3578 -0.0049 0.0643  0.0624  510 PHE   A CE2 
901  C CZ  . PHE   A 137 ? 0.4232 0.5992 0.3626 -0.0071 0.0750  0.0617  510 PHE   A CZ  
902  N N   . VAL   A 138 ? 0.4583 0.5170 0.3720 0.0141  0.0533  0.0079  511 VAL   A N   
903  C CA  . VAL   A 138 ? 0.4551 0.5121 0.3583 0.0106  0.0487  0.0192  511 VAL   A CA  
904  C C   . VAL   A 138 ? 0.4584 0.4978 0.3671 0.0069  0.0430  0.0401  511 VAL   A C   
905  O O   . VAL   A 138 ? 0.4147 0.4339 0.3339 0.0066  0.0407  0.0413  511 VAL   A O   
906  C CB  . VAL   A 138 ? 0.5108 0.5472 0.4098 0.0114  0.0455  0.0056  511 VAL   A CB  
907  C CG1 . VAL   A 138 ? 0.6667 0.6895 0.5625 0.0100  0.0388  0.0168  511 VAL   A CG1 
908  C CG2 . VAL   A 138 ? 0.5274 0.5856 0.4186 0.0121  0.0488  -0.0122 511 VAL   A CG2 
909  N N   . CYS   A 139 ? 0.4288 0.4750 0.3301 0.0046  0.0394  0.0563  512 CYS   A N   
910  C CA  . CYS   A 139 ? 0.4615 0.4834 0.3675 0.0019  0.0318  0.0731  512 CYS   A CA  
911  C C   . CYS   A 139 ? 0.4995 0.5153 0.3967 0.0056  0.0247  0.0792  512 CYS   A C   
912  O O   . CYS   A 139 ? 0.4655 0.5042 0.3525 0.0083  0.0255  0.0764  512 CYS   A O   
913  C CB  . CYS   A 139 ? 0.4752 0.5063 0.3877 -0.0056 0.0332  0.0915  512 CYS   A CB  
914  S SG  . CYS   A 139 ? 0.4600 0.5181 0.3586 -0.0102 0.0339  0.1132  512 CYS   A SG  
915  N N   . SER   A 140 ? 0.4847 0.4702 0.3872 0.0072  0.0171  0.0834  513 SER   A N   
916  C CA  . SER   A 140 ? 0.5029 0.4802 0.4017 0.0129  0.0086  0.0912  513 SER   A CA  
917  C C   . SER   A 140 ? 0.5120 0.4790 0.4120 0.0089  0.0026  0.1153  513 SER   A C   
918  O O   . SER   A 140 ? 0.5278 0.4827 0.4361 0.0010  0.0033  0.1223  513 SER   A O   
919  C CB  . SER   A 140 ? 0.5121 0.4656 0.4156 0.0183  0.0042  0.0795  513 SER   A CB  
920  O OG  . SER   A 140 ? 0.6232 0.5480 0.5341 0.0160  -0.0005 0.0855  513 SER   A OG  
921  N N   . ALA   A 141 ? 0.5200 0.4932 0.4120 0.0134  -0.0037 0.1285  514 ALA   A N   
922  C CA  . ALA   A 141 ? 0.5714 0.5293 0.4627 0.0093  -0.0112 0.1546  514 ALA   A CA  
923  C C   . ALA   A 141 ? 0.5727 0.5107 0.4636 0.0219  -0.0245 0.1594  514 ALA   A C   
924  O O   . ALA   A 141 ? 0.6255 0.5846 0.5087 0.0313  -0.0269 0.1551  514 ALA   A O   
925  C CB  . ALA   A 141 ? 0.5883 0.5786 0.4670 0.0016  -0.0056 0.1711  514 ALA   A CB  
926  N N   . ALA   A 142 ? 0.5772 0.4762 0.4778 0.0231  -0.0337 0.1660  515 ALA   A N   
927  C CA  . ALA   A 142 ? 0.5970 0.4741 0.5010 0.0386  -0.0469 0.1655  515 ALA   A CA  
928  C C   . ALA   A 142 ? 0.6452 0.4912 0.5488 0.0376  -0.0597 0.1933  515 ALA   A C   
929  O O   . ALA   A 142 ? 0.6669 0.4966 0.5729 0.0224  -0.0588 0.2092  515 ALA   A O   
930  C CB  . ALA   A 142 ? 0.5779 0.4335 0.4937 0.0449  -0.0478 0.1425  515 ALA   A CB  
931  N N   . ALA   A 143 ? 0.6753 0.5120 0.5782 0.0545  -0.0727 0.1979  516 ALA   A N   
932  C CA  . ALA   A 143 ? 0.7196 0.5169 0.6241 0.0587  -0.0885 0.2215  516 ALA   A CA  
933  C C   . ALA   A 143 ? 0.7673 0.5174 0.6874 0.0562  -0.0940 0.2137  516 ALA   A C   
934  O O   . ALA   A 143 ? 0.7773 0.5293 0.7055 0.0553  -0.0866 0.1884  516 ALA   A O   
935  C CB  . ALA   A 143 ? 0.7347 0.5354 0.6386 0.0822  -0.1018 0.2210  516 ALA   A CB  
936  N N   . PRO   A 144 ? 0.8141 0.5193 0.7375 0.0540  -0.1078 0.2359  517 PRO   A N   
937  C CA  . PRO   A 144 ? 0.8326 0.4894 0.7715 0.0528  -0.1158 0.2260  517 PRO   A CA  
938  C C   . PRO   A 144 ? 0.8568 0.5053 0.8058 0.0780  -0.1222 0.1960  517 PRO   A C   
939  O O   . PRO   A 144 ? 0.8592 0.5215 0.8066 0.0981  -0.1283 0.1944  517 PRO   A O   
940  C CB  . PRO   A 144 ? 0.8485 0.4588 0.7876 0.0462  -0.1310 0.2585  517 PRO   A CB  
941  C CG  . PRO   A 144 ? 0.8724 0.5133 0.7923 0.0383  -0.1273 0.2903  517 PRO   A CG  
942  C CD  . PRO   A 144 ? 0.8291 0.5268 0.7400 0.0507  -0.1168 0.2723  517 PRO   A CD  
943  N N   . SER   A 145 ? 0.8772 0.5087 0.8365 0.0768  -0.1203 0.1712  518 SER   A N   
944  C CA  . SER   A 145 ? 0.9674 0.5916 0.9360 0.0999  -0.1256 0.1419  518 SER   A CA  
945  C C   . SER   A 145 ? 1.0196 0.5957 0.9976 0.1169  -0.1461 0.1498  518 SER   A C   
946  O O   . SER   A 145 ? 1.0535 0.5896 1.0322 0.1051  -0.1560 0.1739  518 SER   A O   
947  C CB  . SER   A 145 ? 1.0226 0.6429 0.9956 0.0940  -0.1187 0.1144  518 SER   A CB  
948  O OG  . SER   A 145 ? 1.0259 0.6149 1.0021 0.0739  -0.1219 0.1241  518 SER   A OG  
949  N N   . LEU   A 146 ? 1.0856 0.6676 1.0718 0.1444  -0.1526 0.1301  519 LEU   A N   
950  C CA  . LEU   A 146 ? 1.1497 0.6890 1.1467 0.1668  -0.1736 0.1353  519 LEU   A CA  
951  C C   . LEU   A 146 ? 1.1559 0.6414 1.1650 0.1679  -0.1828 0.1177  519 LEU   A C   
952  O O   . LEU   A 146 ? 1.0585 0.5557 1.0671 0.1574  -0.1711 0.0934  519 LEU   A O   
953  C CB  . LEU   A 146 ? 1.2142 0.7879 1.2192 0.1968  -0.1760 0.1163  519 LEU   A CB  
954  C CG  . LEU   A 146 ? 1.2823 0.9057 1.2771 0.1985  -0.1719 0.1332  519 LEU   A CG  
955  C CD1 . LEU   A 146 ? 1.2790 0.9442 1.2860 0.2258  -0.1727 0.1084  519 LEU   A CD1 
956  C CD2 . LEU   A 146 ? 1.3374 0.9341 1.3233 0.1976  -0.1873 0.1738  519 LEU   A CD2 
957  N N   . MET   A 162 ? 1.0657 0.8035 1.0796 0.2080  -0.1166 -0.0078 535 MET   A N   
958  C CA  . MET   A 162 ? 1.1215 0.8107 1.1272 0.1903  -0.1204 0.0037  535 MET   A CA  
959  C C   . MET   A 162 ? 1.1467 0.8443 1.1380 0.1646  -0.1129 0.0315  535 MET   A C   
960  O O   . MET   A 162 ? 1.1384 0.8077 1.1274 0.1575  -0.1224 0.0587  535 MET   A O   
961  C CB  . MET   A 162 ? 1.1406 0.8264 1.1426 0.1842  -0.1117 -0.0235 535 MET   A CB  
962  N N   . ASN   A 163 ? 1.0682 0.8049 1.0498 0.1506  -0.0957 0.0244  536 ASN   A N   
963  C CA  . ASN   A 163 ? 1.0281 0.7833 0.9982 0.1315  -0.0876 0.0456  536 ASN   A CA  
964  C C   . ASN   A 163 ? 0.9428 0.7447 0.9125 0.1383  -0.0826 0.0452  536 ASN   A C   
965  O O   . ASN   A 163 ? 0.9051 0.7324 0.8650 0.1237  -0.0727 0.0533  536 ASN   A O   
966  C CB  . ASN   A 163 ? 1.0175 0.7764 0.9779 0.1105  -0.0748 0.0406  536 ASN   A CB  
967  N N   . GLN   A 164 ? 0.9124 0.7256 0.8944 0.1611  -0.0910 0.0357  537 GLN   A N   
968  C CA  . GLN   A 164 ? 0.8695 0.7278 0.8542 0.1690  -0.0901 0.0361  537 GLN   A CA  
969  C C   . GLN   A 164 ? 0.7984 0.6516 0.7755 0.1684  -0.1007 0.0665  537 GLN   A C   
970  O O   . GLN   A 164 ? 0.8130 0.6716 0.7973 0.1875  -0.1143 0.0731  537 GLN   A O   
971  C CB  . GLN   A 164 ? 1.0199 0.8946 1.0236 0.1961  -0.0985 0.0178  537 GLN   A CB  
972  C CG  . GLN   A 164 ? 1.0911 0.9833 1.1030 0.1995  -0.0872 -0.0143 537 GLN   A CG  
973  C CD  . GLN   A 164 ? 0.9789 0.9085 0.9813 0.1782  -0.0677 -0.0230 537 GLN   A CD  
974  O OE1 . GLN   A 164 ? 0.8032 0.7758 0.8085 0.1760  -0.0631 -0.0248 537 GLN   A OE1 
975  N NE2 . GLN   A 164 ? 0.9584 0.8694 0.9491 0.1620  -0.0577 -0.0281 537 GLN   A NE2 
976  N N   . VAL   A 165 ? 0.7449 0.5907 0.7069 0.1469  -0.0944 0.0850  538 VAL   A N   
977  C CA  . VAL   A 165 ? 0.7619 0.6005 0.7133 0.1433  -0.1030 0.1160  538 VAL   A CA  
978  C C   . VAL   A 165 ? 0.7037 0.5847 0.6411 0.1285  -0.0911 0.1206  538 VAL   A C   
979  O O   . VAL   A 165 ? 0.6790 0.5812 0.6148 0.1169  -0.0762 0.1032  538 VAL   A O   
980  C CB  . VAL   A 165 ? 0.7871 0.5769 0.7344 0.1308  -0.1078 0.1369  538 VAL   A CB  
981  C CG1 . VAL   A 165 ? 0.8216 0.5636 0.7825 0.1466  -0.1234 0.1342  538 VAL   A CG1 
982  C CG2 . VAL   A 165 ? 0.7467 0.5354 0.6898 0.1086  -0.0927 0.1296  538 VAL   A CG2 
983  N N   . PRO   A 166 ? 0.6888 0.5823 0.6144 0.1289  -0.0981 0.1441  539 PRO   A N   
984  C CA  . PRO   A 166 ? 0.6431 0.5763 0.5534 0.1152  -0.0877 0.1478  539 PRO   A CA  
985  C C   . PRO   A 166 ? 0.6008 0.5279 0.5049 0.0931  -0.0723 0.1471  539 PRO   A C   
986  O O   . PRO   A 166 ? 0.6164 0.5081 0.5228 0.0853  -0.0731 0.1576  539 PRO   A O   
987  C CB  . PRO   A 166 ? 0.6780 0.6133 0.5740 0.1191  -0.1002 0.1785  539 PRO   A CB  
988  C CG  . PRO   A 166 ? 0.7148 0.6278 0.6237 0.1435  -0.1195 0.1818  539 PRO   A CG  
989  C CD  . PRO   A 166 ? 0.7217 0.5933 0.6471 0.1446  -0.1177 0.1670  539 PRO   A CD  
990  N N   . GLY   A 167 ? 0.5484 0.5106 0.4470 0.0841  -0.0595 0.1327  540 GLY   A N   
991  C CA  . GLY   A 167 ? 0.5503 0.5153 0.4421 0.0660  -0.0462 0.1335  540 GLY   A CA  
992  C C   . GLY   A 167 ? 0.5269 0.5350 0.4080 0.0604  -0.0374 0.1247  540 GLY   A C   
993  O O   . GLY   A 167 ? 0.5261 0.5618 0.4061 0.0688  -0.0414 0.1156  540 GLY   A O   
994  N N   . ARG   A 168 ? 0.5602 0.5749 0.4352 0.0466  -0.0261 0.1258  541 ARG   A N   
995  C CA  . ARG   A 168 ? 0.5841 0.6364 0.4489 0.0410  -0.0172 0.1149  541 ARG   A CA  
996  C C   . ARG   A 168 ? 0.5207 0.5683 0.3919 0.0321  -0.0047 0.0967  541 ARG   A C   
997  O O   . ARG   A 168 ? 0.5007 0.5198 0.3808 0.0286  -0.0031 0.0986  541 ARG   A O   
998  C CB  . ARG   A 168 ? 0.6152 0.6878 0.4635 0.0347  -0.0159 0.1361  541 ARG   A CB  
999  C CG  . ARG   A 168 ? 0.6857 0.7618 0.5227 0.0423  -0.0293 0.1605  541 ARG   A CG  
1000 C CD  . ARG   A 168 ? 0.7602 0.8623 0.5764 0.0327  -0.0249 0.1811  541 ARG   A CD  
1001 N NE  . ARG   A 168 ? 0.8588 0.9567 0.6608 0.0367  -0.0380 0.2130  541 ARG   A NE  
1002 C CZ  . ARG   A 168 ? 0.9070 1.0167 0.7011 0.0503  -0.0519 0.2179  541 ARG   A CZ  
1003 N NH1 . ARG   A 168 ? 0.9544 1.0869 0.7548 0.0601  -0.0539 0.1912  541 ARG   A NH1 
1004 N NH2 . ARG   A 168 ? 0.9410 1.0397 0.7220 0.0538  -0.0648 0.2506  541 ARG   A NH2 
1005 N N   . LEU   A 169 ? 0.4961 0.5712 0.3621 0.0291  0.0026  0.0792  542 LEU   A N   
1006 C CA  . LEU   A 169 ? 0.4787 0.5509 0.3490 0.0222  0.0133  0.0624  542 LEU   A CA  
1007 C C   . LEU   A 169 ? 0.4923 0.5953 0.3520 0.0178  0.0207  0.0601  542 LEU   A C   
1008 O O   . LEU   A 169 ? 0.4907 0.6228 0.3410 0.0194  0.0203  0.0501  542 LEU   A O   
1009 C CB  . LEU   A 169 ? 0.4775 0.5491 0.3535 0.0229  0.0145  0.0394  542 LEU   A CB  
1010 C CG  . LEU   A 169 ? 0.4937 0.5522 0.3744 0.0167  0.0233  0.0230  542 LEU   A CG  
1011 C CD1 . LEU   A 169 ? 0.5020 0.5286 0.3900 0.0152  0.0240  0.0311  542 LEU   A CD1 
1012 C CD2 . LEU   A 169 ? 0.5308 0.5889 0.4156 0.0144  0.0242  0.0040  542 LEU   A CD2 
1013 N N   . LEU   A 170 ? 0.4561 0.5558 0.3188 0.0126  0.0275  0.0668  543 LEU   A N   
1014 C CA  . LEU   A 170 ? 0.4661 0.5991 0.3201 0.0091  0.0359  0.0660  543 LEU   A CA  
1015 C C   . LEU   A 170 ? 0.4868 0.6215 0.3489 0.0089  0.0449  0.0418  543 LEU   A C   
1016 O O   . LEU   A 170 ? 0.4955 0.6034 0.3710 0.0085  0.0457  0.0386  543 LEU   A O   
1017 C CB  . LEU   A 170 ? 0.4775 0.6115 0.3318 0.0028  0.0375  0.0916  543 LEU   A CB  
1018 C CG  . LEU   A 170 ? 0.5080 0.6447 0.3499 0.0018  0.0293  0.1193  543 LEU   A CG  
1019 C CD1 . LEU   A 170 ? 0.5406 0.6485 0.3858 0.0091  0.0164  0.1243  543 LEU   A CD1 
1020 C CD2 . LEU   A 170 ? 0.5369 0.6681 0.3834 -0.0082 0.0320  0.1426  543 LEU   A CD2 
1021 N N   . LEU   A 171 ? 0.4944 0.6619 0.3473 0.0099  0.0509  0.0260  544 LEU   A N   
1022 C CA  . LEU   A 171 ? 0.4882 0.6597 0.3486 0.0119  0.0591  0.0026  544 LEU   A CA  
1023 C C   . LEU   A 171 ? 0.5044 0.7119 0.3619 0.0109  0.0686  0.0071  544 LEU   A C   
1024 O O   . LEU   A 171 ? 0.5406 0.7822 0.3816 0.0085  0.0704  0.0169  544 LEU   A O   
1025 C CB  . LEU   A 171 ? 0.4757 0.6560 0.3299 0.0141  0.0585  -0.0242 544 LEU   A CB  
1026 C CG  . LEU   A 171 ? 0.4796 0.6621 0.3401 0.0178  0.0653  -0.0519 544 LEU   A CG  
1027 C CD1 . LEU   A 171 ? 0.4819 0.6224 0.3598 0.0196  0.0647  -0.0568 544 LEU   A CD1 
1028 C CD2 . LEU   A 171 ? 0.4988 0.6917 0.3513 0.0173  0.0632  -0.0769 544 LEU   A CD2 
1029 N N   . TRP   A 172 ? 0.4788 0.6807 0.3527 0.0128  0.0744  0.0006  545 TRP   A N   
1030 C CA  . TRP   A 172 ? 0.4957 0.7353 0.3728 0.0119  0.0849  0.0028  545 TRP   A CA  
1031 C C   . TRP   A 172 ? 0.4939 0.7453 0.3807 0.0215  0.0918  -0.0282 545 TRP   A C   
1032 O O   . TRP   A 172 ? 0.5279 0.7450 0.4255 0.0274  0.0872  -0.0442 545 TRP   A O   
1033 C CB  . TRP   A 172 ? 0.5001 0.7279 0.3940 0.0063  0.0848  0.0239  545 TRP   A CB  
1034 C CG  . TRP   A 172 ? 0.5311 0.7410 0.4191 -0.0026 0.0772  0.0540  545 TRP   A CG  
1035 C CD1 . TRP   A 172 ? 0.5289 0.6991 0.4152 -0.0021 0.0660  0.0609  545 TRP   A CD1 
1036 C CD2 . TRP   A 172 ? 0.5336 0.7628 0.4197 -0.0137 0.0804  0.0811  545 TRP   A CD2 
1037 N NE1 . TRP   A 172 ? 0.5189 0.6801 0.4022 -0.0098 0.0608  0.0887  545 TRP   A NE1 
1038 C CE2 . TRP   A 172 ? 0.5403 0.7344 0.4230 -0.0183 0.0690  0.1031  545 TRP   A CE2 
1039 C CE3 . TRP   A 172 ? 0.5772 0.8512 0.4641 -0.0209 0.0921  0.0887  545 TRP   A CE3 
1040 C CZ2 . TRP   A 172 ? 0.6145 0.8103 0.4943 -0.0301 0.0674  0.1334  545 TRP   A CZ2 
1041 C CZ3 . TRP   A 172 ? 0.6690 0.9492 0.5521 -0.0351 0.0922  0.1205  545 TRP   A CZ3 
1042 C CH2 . TRP   A 172 ? 0.7015 0.9395 0.5811 -0.0399 0.0792  0.1432  545 TRP   A CH2 
1043 N N   . ASP   A 173 ? 0.5011 0.7999 0.3863 0.0226  0.1029  -0.0336 546 ASP   A N   
1044 C CA  . ASP   A 173 ? 0.5253 0.8426 0.4249 0.0336  0.1109  -0.0611 546 ASP   A CA  
1045 C C   . ASP   A 173 ? 0.5286 0.8545 0.4523 0.0330  0.1153  -0.0492 546 ASP   A C   
1046 O O   . ASP   A 173 ? 0.5081 0.8659 0.4301 0.0226  0.1217  -0.0271 546 ASP   A O   
1047 C CB  . ASP   A 173 ? 0.5716 0.9443 0.4543 0.0357  0.1214  -0.0766 546 ASP   A CB  
1048 C CG  . ASP   A 173 ? 0.5860 0.9880 0.4831 0.0489  0.1314  -0.1079 546 ASP   A CG  
1049 O OD1 . ASP   A 173 ? 0.6309 1.0045 0.5370 0.0604  0.1267  -0.1356 546 ASP   A OD1 
1050 O OD2 . ASP   A 173 ? 0.6914 1.1441 0.5915 0.0474  0.1436  -0.1037 546 ASP   A OD2 
1051 N N   . THR   A 174 ? 0.5141 0.8125 0.4602 0.0434  0.1112  -0.0636 547 THR   A N   
1052 C CA  . THR   A 174 ? 0.4946 0.8006 0.4668 0.0442  0.1125  -0.0548 547 THR   A CA  
1053 C C   . THR   A 174 ? 0.4950 0.8639 0.4785 0.0488  0.1270  -0.0665 547 THR   A C   
1054 O O   . THR   A 174 ? 0.5419 0.9374 0.5426 0.0422  0.1317  -0.0516 547 THR   A O   
1055 C CB  . THR   A 174 ? 0.4754 0.7360 0.4661 0.0561  0.1022  -0.0668 547 THR   A CB  
1056 O OG1 . THR   A 174 ? 0.4753 0.7349 0.4683 0.0720  0.1038  -0.0990 547 THR   A OG1 
1057 C CG2 . THR   A 174 ? 0.4577 0.6614 0.4376 0.0498  0.0897  -0.0537 547 THR   A CG2 
1058 N N   . LYS   A 175 ? 0.5288 0.9239 0.5041 0.0596  0.1342  -0.0947 548 LYS   A N   
1059 C CA  . LYS   A 175 ? 0.5585 1.0159 0.5467 0.0672  0.1488  -0.1115 548 LYS   A CA  
1060 C C   . LYS   A 175 ? 0.5875 1.0983 0.5632 0.0488  0.1609  -0.0856 548 LYS   A C   
1061 O O   . LYS   A 175 ? 0.5867 1.1467 0.5818 0.0467  0.1722  -0.0829 548 LYS   A O   
1062 C CB  . LYS   A 175 ? 0.6083 1.0826 0.5887 0.0835  0.1538  -0.1509 548 LYS   A CB  
1063 N N   . THR   A 176 ? 0.5558 1.0595 0.4997 0.0358  0.1585  -0.0669 549 THR   A N   
1064 C CA  . THR   A 176 ? 0.5627 1.1130 0.4882 0.0180  0.1687  -0.0399 549 THR   A CA  
1065 C C   . THR   A 176 ? 0.5512 1.0679 0.4776 0.0000  0.1600  0.0009  549 THR   A C   
1066 O O   . THR   A 176 ? 0.5532 1.1014 0.4722 -0.0170 0.1674  0.0285  549 THR   A O   
1067 C CB  . THR   A 176 ? 0.5590 1.1286 0.4471 0.0168  0.1706  -0.0452 549 THR   A CB  
1068 O OG1 . THR   A 176 ? 0.5128 1.0238 0.3889 0.0169  0.1542  -0.0394 549 THR   A OG1 
1069 C CG2 . THR   A 176 ? 0.5752 1.1822 0.4598 0.0331  0.1797  -0.0874 549 THR   A CG2 
1070 N N   . MET   A 177 ? 0.5303 0.9831 0.4646 0.0034  0.1444  0.0038  550 MET   A N   
1071 C CA  . MET   A 177 ? 0.5502 0.9619 0.4826 -0.0102 0.1334  0.0365  550 MET   A CA  
1072 C C   . MET   A 177 ? 0.6100 1.0266 0.5103 -0.0214 0.1319  0.0602  550 MET   A C   
1073 O O   . MET   A 177 ? 0.5857 0.9948 0.4830 -0.0368 0.1292  0.0927  550 MET   A O   
1074 C CB  . MET   A 177 ? 0.5537 0.9767 0.5113 -0.0224 0.1363  0.0558  550 MET   A CB  
1075 C CG  . MET   A 177 ? 0.5590 0.9671 0.5493 -0.0111 0.1321  0.0375  550 MET   A CG  
1076 S SD  . MET   A 177 ? 0.5243 0.8532 0.5157 -0.0026 0.1125  0.0336  550 MET   A SD  
1077 C CE  . MET   A 177 ? 0.5238 0.8243 0.5124 -0.0236 0.1039  0.0716  550 MET   A CE  
1078 N N   . LYS   A 178 ? 0.6504 1.0772 0.5273 -0.0131 0.1319  0.0433  551 LYS   A N   
1079 C CA  . LYS   A 178 ? 0.6210 1.0507 0.4666 -0.0196 0.1269  0.0622  551 LYS   A CA  
1080 C C   . LYS   A 178 ? 0.6067 0.9885 0.4465 -0.0110 0.1120  0.0523  551 LYS   A C   
1081 O O   . LYS   A 178 ? 0.5553 0.9170 0.4068 0.0000  0.1097  0.0240  551 LYS   A O   
1082 C CB  . LYS   A 178 ? 0.6491 1.1417 0.4719 -0.0191 0.1397  0.0514  551 LYS   A CB  
1083 C CG  . LYS   A 178 ? 0.6867 1.2325 0.5103 -0.0327 0.1554  0.0706  551 LYS   A CG  
1084 C CD  . LYS   A 178 ? 0.7491 1.3648 0.5500 -0.0315 0.1707  0.0563  551 LYS   A CD  
1085 C CE  . LYS   A 178 ? 0.7820 1.4548 0.5796 -0.0489 0.1875  0.0807  551 LYS   A CE  
1086 N N   . GLN   A 179 ? 0.6007 0.9644 0.4235 -0.0162 0.1017  0.0766  552 GLN   A N   
1087 C CA  . GLN   A 179 ? 0.5802 0.9121 0.3966 -0.0086 0.0890  0.0669  552 GLN   A CA  
1088 C C   . GLN   A 179 ? 0.5335 0.8972 0.3326 -0.0014 0.0915  0.0394  552 GLN   A C   
1089 O O   . GLN   A 179 ? 0.5111 0.9217 0.2913 -0.0039 0.0992  0.0403  552 GLN   A O   
1090 C CB  . GLN   A 179 ? 0.6107 0.9268 0.4121 -0.0130 0.0772  0.0972  552 GLN   A CB  
1091 C CG  . GLN   A 179 ? 0.6450 0.9226 0.4608 -0.0201 0.0712  0.1242  552 GLN   A CG  
1092 C CD  . GLN   A 179 ? 0.6860 0.9433 0.4878 -0.0200 0.0573  0.1493  552 GLN   A CD  
1093 O OE1 . GLN   A 179 ? 0.7027 0.9485 0.4995 -0.0105 0.0477  0.1386  552 GLN   A OE1 
1094 N NE2 . GLN   A 179 ? 0.7224 0.9792 0.5174 -0.0307 0.0561  0.1827  552 GLN   A NE2 
1095 N N   . GLN   A 180 ? 0.5320 0.8701 0.3371 0.0059  0.0845  0.0151  553 GLN   A N   
1096 C CA  . GLN   A 180 ? 0.5392 0.9017 0.3295 0.0109  0.0840  -0.0122 553 GLN   A CA  
1097 C C   . GLN   A 180 ? 0.5264 0.8822 0.3029 0.0105  0.0705  -0.0027 553 GLN   A C   
1098 O O   . GLN   A 180 ? 0.4899 0.8818 0.2440 0.0108  0.0682  -0.0053 553 GLN   A O   
1099 C CB  . GLN   A 180 ? 0.5557 0.8932 0.3644 0.0174  0.0851  -0.0462 553 GLN   A CB  
1100 C CG  . GLN   A 180 ? 0.5790 0.9376 0.3766 0.0214  0.0847  -0.0801 553 GLN   A CG  
1101 C CD  . GLN   A 180 ? 0.5929 0.9161 0.4096 0.0262  0.0840  -0.1102 553 GLN   A CD  
1102 O OE1 . GLN   A 180 ? 0.6580 0.9527 0.4944 0.0292  0.0867  -0.1084 553 GLN   A OE1 
1103 N NE2 . GLN   A 180 ? 0.5934 0.9169 0.4046 0.0261  0.0791  -0.1368 553 GLN   A NE2 
1104 N N   . LEU   A 181 ? 0.5016 0.8137 0.2924 0.0109  0.0613  0.0062  554 LEU   A N   
1105 C CA  . LEU   A 181 ? 0.5176 0.8261 0.3005 0.0127  0.0484  0.0117  554 LEU   A CA  
1106 C C   . LEU   A 181 ? 0.5002 0.7649 0.2988 0.0132  0.0406  0.0297  554 LEU   A C   
1107 O O   . LEU   A 181 ? 0.4742 0.7099 0.2888 0.0114  0.0449  0.0336  554 LEU   A O   
1108 C CB  . LEU   A 181 ? 0.5196 0.8357 0.3033 0.0147  0.0457  -0.0221 554 LEU   A CB  
1109 C CG  . LEU   A 181 ? 0.5058 0.7847 0.3114 0.0142  0.0485  -0.0449 554 LEU   A CG  
1110 C CD1 . LEU   A 181 ? 0.4976 0.7423 0.3162 0.0135  0.0402  -0.0367 554 LEU   A CD1 
1111 C CD2 . LEU   A 181 ? 0.5336 0.8266 0.3373 0.0137  0.0499  -0.0811 554 LEU   A CD2 
1112 N N   A GLN   A 182 ? 0.5194 0.7830 0.3130 0.0169  0.0284  0.0395  555 GLN   A N   
1113 N N   B GLN   A 182 ? 0.5152 0.7783 0.3094 0.0169  0.0284  0.0385  555 GLN   A N   
1114 C CA  A GLN   A 182 ? 0.5093 0.7358 0.3181 0.0201  0.0198  0.0493  555 GLN   A CA  
1115 C CA  B GLN   A 182 ? 0.5037 0.7291 0.3130 0.0200  0.0202  0.0489  555 GLN   A CA  
1116 C C   A GLN   A 182 ? 0.5073 0.7367 0.3230 0.0231  0.0138  0.0269  555 GLN   A C   
1117 C C   B GLN   A 182 ? 0.5047 0.7334 0.3203 0.0234  0.0134  0.0283  555 GLN   A C   
1118 O O   A GLN   A 182 ? 0.5335 0.7965 0.3380 0.0248  0.0089  0.0176  555 GLN   A O   
1119 O O   B GLN   A 182 ? 0.5294 0.7917 0.3336 0.0255  0.0078  0.0210  555 GLN   A O   
1120 C CB  A GLN   A 182 ? 0.5315 0.7537 0.3323 0.0241  0.0089  0.0813  555 GLN   A CB  
1121 C CB  B GLN   A 182 ? 0.5239 0.7433 0.3255 0.0228  0.0109  0.0827  555 GLN   A CB  
1122 C CG  A GLN   A 182 ? 0.5411 0.7562 0.3488 0.0333  -0.0045 0.0799  555 GLN   A CG  
1123 C CG  B GLN   A 182 ? 0.5471 0.7698 0.3405 0.0155  0.0175  0.1065  555 GLN   A CG  
1124 C CD  A GLN   A 182 ? 0.5348 0.7358 0.3388 0.0406  -0.0175 0.1105  555 GLN   A CD  
1125 C CD  B GLN   A 182 ? 0.5713 0.7831 0.3556 0.0166  0.0067  0.1419  555 GLN   A CD  
1126 O OE1 A GLN   A 182 ? 0.5064 0.7099 0.3145 0.0511  -0.0300 0.1109  555 GLN   A OE1 
1127 O OE1 B GLN   A 182 ? 0.6225 0.8281 0.4051 0.0259  -0.0068 0.1480  555 GLN   A OE1 
1128 N NE2 A GLN   A 182 ? 0.5500 0.7381 0.3468 0.0349  -0.0151 0.1361  555 GLN   A NE2 
1129 N NE2 B GLN   A 182 ? 0.5579 0.7669 0.3381 0.0071  0.0120  0.1657  555 GLN   A NE2 
1130 N N   . PHE   A 183 ? 0.5024 0.6993 0.3362 0.0228  0.0139  0.0192  556 PHE   A N   
1131 C CA  . PHE   A 183 ? 0.5007 0.7000 0.3444 0.0232  0.0094  0.0005  556 PHE   A CA  
1132 C C   . PHE   A 183 ? 0.5220 0.7250 0.3692 0.0322  -0.0029 0.0147  556 PHE   A C   
1133 O O   . PHE   A 183 ? 0.5596 0.7359 0.4125 0.0370  -0.0061 0.0327  556 PHE   A O   
1134 C CB  . PHE   A 183 ? 0.4604 0.6244 0.3196 0.0180  0.0160  -0.0108 556 PHE   A CB  
1135 C CG  . PHE   A 183 ? 0.4703 0.6257 0.3294 0.0116  0.0260  -0.0270 556 PHE   A CG  
1136 C CD1 . PHE   A 183 ? 0.4903 0.6549 0.3506 0.0058  0.0283  -0.0525 556 PHE   A CD1 
1137 C CD2 . PHE   A 183 ? 0.5087 0.6454 0.3690 0.0118  0.0319  -0.0174 556 PHE   A CD2 
1138 C CE1 . PHE   A 183 ? 0.5155 0.6665 0.3774 0.0023  0.0357  -0.0679 556 PHE   A CE1 
1139 C CE2 . PHE   A 183 ? 0.5237 0.6523 0.3869 0.0092  0.0395  -0.0333 556 PHE   A CE2 
1140 C CZ  . PHE   A 183 ? 0.5160 0.6498 0.3794 0.0055  0.0412  -0.0582 556 PHE   A CZ  
1141 N N   . SER   A 184 ? 0.5159 0.7522 0.3612 0.0352  -0.0107 0.0046  557 SER   A N   
1142 C CA  . SER   A 184 ? 0.5523 0.7953 0.4064 0.0461  -0.0232 0.0127  557 SER   A CA  
1143 C C   . SER   A 184 ? 0.5451 0.7625 0.4206 0.0453  -0.0198 0.0028  557 SER   A C   
1144 O O   . SER   A 184 ? 0.5081 0.7173 0.3905 0.0344  -0.0102 -0.0160 557 SER   A O   
1145 C CB  . SER   A 184 ? 0.5555 0.8442 0.4061 0.0489  -0.0325 0.0008  557 SER   A CB  
1146 O OG  . SER   A 184 ? 0.5997 0.9136 0.4262 0.0486  -0.0345 0.0093  557 SER   A OG  
1147 N N   . LEU   A 185 ? 0.5562 0.7593 0.4404 0.0571  -0.0278 0.0166  558 LEU   A N   
1148 C CA  . LEU   A 185 ? 0.5317 0.7153 0.4344 0.0587  -0.0250 0.0077  558 LEU   A CA  
1149 C C   . LEU   A 185 ? 0.5165 0.7295 0.4340 0.0704  -0.0354 0.0004  558 LEU   A C   
1150 O O   . LEU   A 185 ? 0.5652 0.7853 0.4812 0.0856  -0.0488 0.0157  558 LEU   A O   
1151 C CB  . LEU   A 185 ? 0.5102 0.6522 0.4124 0.0643  -0.0261 0.0267  558 LEU   A CB  
1152 C CG  . LEU   A 185 ? 0.5019 0.6180 0.3939 0.0533  -0.0165 0.0341  558 LEU   A CG  
1153 C CD1 . LEU   A 185 ? 0.5087 0.5872 0.4034 0.0580  -0.0199 0.0515  558 LEU   A CD1 
1154 C CD2 . LEU   A 185 ? 0.4845 0.5947 0.3805 0.0407  -0.0042 0.0139  558 LEU   A CD2 
1155 N N   . ASP   A 186 ? 0.5376 0.7669 0.4705 0.0635  -0.0294 -0.0217 559 ASP   A N   
1156 C CA  . ASP   A 186 ? 0.5717 0.8367 0.5234 0.0742  -0.0381 -0.0316 559 ASP   A CA  
1157 C C   . ASP   A 186 ? 0.5123 0.7609 0.4810 0.0814  -0.0349 -0.0359 559 ASP   A C   
1158 O O   . ASP   A 186 ? 0.4919 0.7136 0.4592 0.0698  -0.0223 -0.0407 559 ASP   A O   
1159 C CB  . ASP   A 186 ? 0.6283 0.9335 0.5879 0.0601  -0.0344 -0.0549 559 ASP   A CB  
1160 C CG  . ASP   A 186 ? 0.7385 1.0948 0.7143 0.0717  -0.0476 -0.0629 559 ASP   A CG  
1161 O OD1 . ASP   A 186 ? 0.8938 1.2734 0.8583 0.0794  -0.0603 -0.0552 559 ASP   A OD1 
1162 O OD2 . ASP   A 186 ? 0.7349 1.1091 0.7341 0.0747  -0.0460 -0.0755 559 ASP   A OD2 
1163 N N   . PRO   A 187 ? 0.5315 0.7970 0.5166 0.1015  -0.0461 -0.0357 560 PRO   A N   
1164 C CA  . PRO   A 187 ? 0.5642 0.8631 0.5525 0.1182  -0.0637 -0.0292 560 PRO   A CA  
1165 C C   . PRO   A 187 ? 0.6090 0.8797 0.5789 0.1309  -0.0763 -0.0005 560 PRO   A C   
1166 O O   . PRO   A 187 ? 0.5840 0.8790 0.5487 0.1421  -0.0911 0.0096  560 PRO   A O   
1167 C CB  . PRO   A 187 ? 0.5365 0.8592 0.5533 0.1361  -0.0694 -0.0420 560 PRO   A CB  
1168 C CG  . PRO   A 187 ? 0.5227 0.8026 0.5419 0.1374  -0.0602 -0.0421 560 PRO   A CG  
1169 C CD  . PRO   A 187 ? 0.5313 0.7856 0.5330 0.1109  -0.0431 -0.0433 560 PRO   A CD  
1170 N N   . GLU   A 188 ? 0.6529 0.8735 0.6126 0.1277  -0.0707 0.0131  561 GLU   A N   
1171 C CA  . GLU   A 188 ? 0.6895 0.8782 0.6339 0.1364  -0.0812 0.0418  561 GLU   A CA  
1172 C C   . GLU   A 188 ? 0.6118 0.7592 0.5420 0.1204  -0.0690 0.0513  561 GLU   A C   
1173 O O   . GLU   A 188 ? 0.5390 0.6712 0.4756 0.1108  -0.0565 0.0371  561 GLU   A O   
1174 C CB  . GLU   A 188 ? 0.7686 0.9308 0.7267 0.1585  -0.0937 0.0499  561 GLU   A CB  
1175 C CG  . GLU   A 188 ? 0.8766 1.0738 0.8514 0.1815  -0.1104 0.0454  561 GLU   A CG  
1176 C CD  . GLU   A 188 ? 0.9357 1.0967 0.9200 0.2054  -0.1257 0.0584  561 GLU   A CD  
1177 O OE1 . GLU   A 188 ? 0.8631 0.9856 0.8542 0.2054  -0.1195 0.0531  561 GLU   A OE1 
1178 O OE2 . GLU   A 188 ? 1.0854 1.2549 1.0689 0.2239  -0.1449 0.0742  561 GLU   A OE2 
1179 N N   . PRO   A 189 ? 0.6045 0.7339 0.5160 0.1181  -0.0734 0.0769  562 PRO   A N   
1180 C CA  . PRO   A 189 ? 0.5882 0.6789 0.4910 0.1056  -0.0646 0.0885  562 PRO   A CA  
1181 C C   . PRO   A 189 ? 0.5822 0.6342 0.4996 0.1106  -0.0642 0.0837  562 PRO   A C   
1182 O O   . PRO   A 189 ? 0.6385 0.6797 0.5678 0.1279  -0.0759 0.0848  562 PRO   A O   
1183 C CB  . PRO   A 189 ? 0.6141 0.6954 0.4987 0.1067  -0.0738 0.1206  562 PRO   A CB  
1184 C CG  . PRO   A 189 ? 0.6195 0.7464 0.4948 0.1137  -0.0827 0.1217  562 PRO   A CG  
1185 C CD  . PRO   A 189 ? 0.6342 0.7840 0.5315 0.1264  -0.0873 0.0969  562 PRO   A CD  
1186 N N   . ILE   A 190 ? 0.5358 0.5678 0.4521 0.0965  -0.0515 0.0768  563 ILE   A N   
1187 C CA  . ILE   A 190 ? 0.5422 0.5429 0.4697 0.0994  -0.0500 0.0681  563 ILE   A CA  
1188 C C   . ILE   A 190 ? 0.5086 0.4838 0.4290 0.0833  -0.0405 0.0725  563 ILE   A C   
1189 O O   . ILE   A 190 ? 0.4994 0.4894 0.4110 0.0703  -0.0309 0.0715  563 ILE   A O   
1190 C CB  . ILE   A 190 ? 0.5360 0.5592 0.4761 0.1026  -0.0438 0.0413  563 ILE   A CB  
1191 C CG1 . ILE   A 190 ? 0.5582 0.5539 0.5078 0.1078  -0.0426 0.0306  563 ILE   A CG1 
1192 C CG2 . ILE   A 190 ? 0.5085 0.5537 0.4428 0.0852  -0.0296 0.0279  563 ILE   A CG2 
1193 C CD1 . ILE   A 190 ? 0.5594 0.5377 0.5203 0.1290  -0.0574 0.0345  563 ILE   A CD1 
1194 N N   . ALA   A 191 ? 0.5237 0.4617 0.4493 0.0852  -0.0442 0.0760  564 ALA   A N   
1195 C CA  . ALA   A 191 ? 0.5271 0.4423 0.4492 0.0711  -0.0374 0.0791  564 ALA   A CA  
1196 C C   . ALA   A 191 ? 0.5037 0.4300 0.4250 0.0627  -0.0248 0.0589  564 ALA   A C   
1197 O O   . ALA   A 191 ? 0.4942 0.4240 0.4210 0.0681  -0.0229 0.0418  564 ALA   A O   
1198 C CB  . ALA   A 191 ? 0.5604 0.4354 0.4895 0.0753  -0.0460 0.0836  564 ALA   A CB  
1199 N N   . ILE   A 192 ? 0.4625 0.3943 0.3771 0.0498  -0.0163 0.0613  565 ILE   A N   
1200 C CA  . ILE   A 192 ? 0.4977 0.4322 0.4103 0.0416  -0.0062 0.0458  565 ILE   A CA  
1201 C C   . ILE   A 192 ? 0.4987 0.4055 0.4117 0.0353  -0.0057 0.0485  565 ILE   A C   
1202 O O   . ILE   A 192 ? 0.4776 0.3772 0.3910 0.0301  -0.0073 0.0620  565 ILE   A O   
1203 C CB  . ILE   A 192 ? 0.5359 0.4963 0.4426 0.0345  0.0014  0.0421  565 ILE   A CB  
1204 C CG1 . ILE   A 192 ? 0.5413 0.5308 0.4493 0.0394  0.0006  0.0322  565 ILE   A CG1 
1205 C CG2 . ILE   A 192 ? 0.5197 0.4720 0.4241 0.0251  0.0100  0.0320  565 ILE   A CG2 
1206 C CD1 . ILE   A 192 ? 0.5548 0.5706 0.4572 0.0329  0.0062  0.0253  565 ILE   A CD1 
1207 N N   . ASN   A 193 ? 0.4678 0.3630 0.3803 0.0350  -0.0034 0.0355  566 ASN   A N   
1208 C CA  . ASN   A 193 ? 0.4992 0.3690 0.4112 0.0308  -0.0056 0.0362  566 ASN   A CA  
1209 C C   . ASN   A 193 ? 0.5026 0.3731 0.4095 0.0215  0.0010  0.0337  566 ASN   A C   
1210 O O   . ASN   A 193 ? 0.5612 0.4178 0.4696 0.0172  -0.0016 0.0384  566 ASN   A O   
1211 C CB  . ASN   A 193 ? 0.5026 0.3604 0.4137 0.0364  -0.0079 0.0235  566 ASN   A CB  
1212 C CG  . ASN   A 193 ? 0.5033 0.3561 0.4221 0.0489  -0.0163 0.0234  566 ASN   A CG  
1213 O OD1 . ASN   A 193 ? 0.5786 0.4201 0.5028 0.0511  -0.0242 0.0376  566 ASN   A OD1 
1214 N ND2 . ASN   A 193 ? 0.5008 0.3625 0.4210 0.0574  -0.0148 0.0081  566 ASN   A ND2 
1215 N N   . CYS   A 194 ? 0.4927 0.3783 0.3948 0.0187  0.0087  0.0254  567 CYS   A N   
1216 C CA  . CYS   A 194 ? 0.4746 0.3546 0.3716 0.0119  0.0136  0.0219  567 CYS   A CA  
1217 C C   . CYS   A 194 ? 0.4561 0.3533 0.3517 0.0086  0.0203  0.0166  567 CYS   A C   
1218 O O   . CYS   A 194 ? 0.4968 0.4122 0.3932 0.0096  0.0225  0.0112  567 CYS   A O   
1219 C CB  . CYS   A 194 ? 0.4977 0.3639 0.3860 0.0096  0.0148  0.0141  567 CYS   A CB  
1220 S SG  . CYS   A 194 ? 0.5096 0.3913 0.3954 0.0108  0.0200  0.0021  567 CYS   A SG  
1221 N N   . THR   A 195 ? 0.4697 0.3615 0.3649 0.0054  0.0225  0.0166  568 THR   A N   
1222 C CA  . THR   A 195 ? 0.4961 0.3997 0.3911 0.0031  0.0278  0.0094  568 THR   A CA  
1223 C C   . THR   A 195 ? 0.5262 0.4096 0.4182 0.0005  0.0287  0.0059  568 THR   A C   
1224 O O   . THR   A 195 ? 0.4766 0.3468 0.3703 0.0027  0.0244  0.0122  568 THR   A O   
1225 C CB  . THR   A 195 ? 0.5065 0.4299 0.4070 0.0061  0.0282  0.0144  568 THR   A CB  
1226 O OG1 . THR   A 195 ? 0.5012 0.4149 0.4075 0.0071  0.0252  0.0229  568 THR   A OG1 
1227 C CG2 . THR   A 195 ? 0.5187 0.4603 0.4195 0.0089  0.0258  0.0216  568 THR   A CG2 
1228 N N   . ALA   A 196 ? 0.5054 0.3873 0.3944 -0.0036 0.0330  -0.0040 569 ALA   A N   
1229 C CA  . ALA   A 196 ? 0.5258 0.3855 0.4128 -0.0042 0.0325  -0.0067 569 ALA   A CA  
1230 C C   . ALA   A 196 ? 0.5141 0.3772 0.4024 -0.0071 0.0366  -0.0197 569 ALA   A C   
1231 O O   . ALA   A 196 ? 0.5351 0.4084 0.4212 -0.0141 0.0400  -0.0268 569 ALA   A O   
1232 C CB  . ALA   A 196 ? 0.5268 0.3613 0.4025 -0.0101 0.0311  -0.0027 569 ALA   A CB  
1233 N N   . PHE   A 197 ? 0.5014 0.3558 0.3948 -0.0012 0.0353  -0.0243 570 PHE   A N   
1234 C CA  . PHE   A 197 ? 0.5190 0.3691 0.4141 -0.0026 0.0377  -0.0395 570 PHE   A CA  
1235 C C   . PHE   A 197 ? 0.5066 0.3176 0.3947 -0.0091 0.0355  -0.0393 570 PHE   A C   
1236 O O   . PHE   A 197 ? 0.5136 0.3046 0.3966 -0.0079 0.0313  -0.0275 570 PHE   A O   
1237 C CB  . PHE   A 197 ? 0.4904 0.3498 0.3956 0.0090  0.0375  -0.0479 570 PHE   A CB  
1238 C CG  . PHE   A 197 ? 0.4800 0.3809 0.3896 0.0130  0.0418  -0.0517 570 PHE   A CG  
1239 C CD1 . PHE   A 197 ? 0.4730 0.3933 0.3801 0.0103  0.0456  -0.0669 570 PHE   A CD1 
1240 C CD2 . PHE   A 197 ? 0.4631 0.3842 0.3782 0.0180  0.0417  -0.0391 570 PHE   A CD2 
1241 C CE1 . PHE   A 197 ? 0.4689 0.4290 0.3762 0.0141  0.0492  -0.0688 570 PHE   A CE1 
1242 C CE2 . PHE   A 197 ? 0.4556 0.4140 0.3720 0.0199  0.0460  -0.0394 570 PHE   A CE2 
1243 C CZ  . PHE   A 197 ? 0.4593 0.4379 0.3704 0.0187  0.0499  -0.0537 570 PHE   A CZ  
1244 N N   . ASN   A 198 ? 0.5452 0.3454 0.4329 -0.0161 0.0374  -0.0526 571 ASN   A N   
1245 C CA  . ASN   A 198 ? 0.5830 0.3407 0.4650 -0.0226 0.0345  -0.0523 571 ASN   A CA  
1246 C C   . ASN   A 198 ? 0.6329 0.3709 0.5230 -0.0076 0.0287  -0.0582 571 ASN   A C   
1247 O O   . ASN   A 198 ? 0.6777 0.4401 0.5779 0.0064  0.0284  -0.0614 571 ASN   A O   
1248 C CB  . ASN   A 198 ? 0.5829 0.3363 0.4629 -0.0394 0.0385  -0.0638 571 ASN   A CB  
1249 C CG  . ASN   A 198 ? 0.5795 0.3450 0.4690 -0.0354 0.0391  -0.0859 571 ASN   A CG  
1250 O OD1 . ASN   A 198 ? 0.5449 0.3373 0.4411 -0.0214 0.0393  -0.0920 571 ASN   A OD1 
1251 N ND2 . ASN   A 198 ? 0.6119 0.3601 0.5018 -0.0490 0.0395  -0.0987 571 ASN   A ND2 
1252 N N   . HIS   A 199 ? 0.6292 0.3229 0.5153 -0.0105 0.0239  -0.0586 572 HIS   A N   
1253 C CA  . HIS   A 199 ? 0.7252 0.3945 0.6190 0.0065  0.0157  -0.0605 572 HIS   A CA  
1254 C C   . HIS   A 199 ? 0.6927 0.3829 0.6023 0.0194  0.0177  -0.0844 572 HIS   A C   
1255 O O   . HIS   A 199 ? 0.7196 0.4227 0.6414 0.0377  0.0149  -0.0877 572 HIS   A O   
1256 C CB  . HIS   A 199 ? 0.8405 0.4516 0.7245 0.0008  0.0082  -0.0524 572 HIS   A CB  
1257 C CG  . HIS   A 199 ? 1.0497 0.6321 0.9427 0.0217  -0.0029 -0.0534 572 HIS   A CG  
1258 N ND1 . HIS   A 199 ? 1.2184 0.7698 1.1208 0.0299  -0.0079 -0.0706 572 HIS   A ND1 
1259 C CD2 . HIS   A 199 ? 1.1284 0.7090 1.0239 0.0374  -0.0114 -0.0403 572 HIS   A CD2 
1260 C CE1 . HIS   A 199 ? 1.1681 0.7007 1.0795 0.0517  -0.0189 -0.0679 572 HIS   A CE1 
1261 N NE2 . HIS   A 199 ? 1.1700 0.7216 1.0775 0.0559  -0.0214 -0.0489 572 HIS   A NE2 
1262 N N   . ASN   A 200 ? 0.6833 0.3771 0.5931 0.0098  0.0221  -0.1026 573 ASN   A N   
1263 C CA  . ASN   A 200 ? 0.7457 0.4596 0.6673 0.0216  0.0240  -0.1282 573 ASN   A CA  
1264 C C   . ASN   A 200 ? 0.6977 0.4723 0.6204 0.0225  0.0323  -0.1321 573 ASN   A C   
1265 O O   . ASN   A 200 ? 0.6937 0.4958 0.6236 0.0326  0.0353  -0.1512 573 ASN   A O   
1266 C CB  . ASN   A 200 ? 0.8796 0.5609 0.8013 0.0127  0.0219  -0.1484 573 ASN   A CB  
1267 C CG  . ASN   A 200 ? 1.0423 0.7482 0.9583 -0.0069 0.0281  -0.1572 573 ASN   A CG  
1268 O OD1 . ASN   A 200 ? 1.3277 1.0395 1.2479 -0.0089 0.0286  -0.1827 573 ASN   A OD1 
1269 N ND2 . ASN   A 200 ? 1.0424 0.7630 0.9497 -0.0211 0.0318  -0.1386 573 ASN   A ND2 
1270 N N   . GLY   A 201 ? 0.6111 0.4063 0.5259 0.0124  0.0355  -0.1140 574 GLY   A N   
1271 C CA  . GLY   A 201 ? 0.5741 0.4201 0.4892 0.0148  0.0409  -0.1119 574 GLY   A CA  
1272 C C   . GLY   A 201 ? 0.5946 0.4681 0.5048 0.0052  0.0448  -0.1262 574 GLY   A C   
1273 O O   . GLY   A 201 ? 0.5918 0.5068 0.4996 0.0070  0.0483  -0.1235 574 GLY   A O   
1274 N N   . ASN   A 202 ? 0.6046 0.4557 0.5127 -0.0069 0.0434  -0.1389 575 ASN   A N   
1275 C CA  . ASN   A 202 ? 0.6027 0.4833 0.5076 -0.0176 0.0455  -0.1525 575 ASN   A CA  
1276 C C   . ASN   A 202 ? 0.5590 0.4553 0.4593 -0.0298 0.0466  -0.1366 575 ASN   A C   
1277 O O   . ASN   A 202 ? 0.5274 0.4551 0.4265 -0.0365 0.0470  -0.1455 575 ASN   A O   
1278 C CB  . ASN   A 202 ? 0.7173 0.5727 0.6248 -0.0273 0.0431  -0.1760 575 ASN   A CB  
1279 C CG  . ASN   A 202 ? 0.8267 0.6369 0.7330 -0.0435 0.0411  -0.1659 575 ASN   A CG  
1280 O OD1 . ASN   A 202 ? 0.8841 0.6598 0.7889 -0.0391 0.0389  -0.1495 575 ASN   A OD1 
1281 N ND2 . ASN   A 202 ? 0.8469 0.6588 0.7535 -0.0633 0.0415  -0.1747 575 ASN   A ND2 
1282 N N   . LEU   A 203 ? 0.5511 0.4286 0.4491 -0.0313 0.0463  -0.1148 576 LEU   A N   
1283 C CA  . LEU   A 203 ? 0.4993 0.3952 0.3944 -0.0389 0.0477  -0.1019 576 LEU   A CA  
1284 C C   . LEU   A 203 ? 0.4907 0.3898 0.3841 -0.0282 0.0469  -0.0816 576 LEU   A C   
1285 O O   . LEU   A 203 ? 0.5284 0.4041 0.4220 -0.0210 0.0451  -0.0740 576 LEU   A O   
1286 C CB  . LEU   A 203 ? 0.5264 0.3997 0.4197 -0.0561 0.0491  -0.0992 576 LEU   A CB  
1287 C CG  . LEU   A 203 ? 0.5826 0.4463 0.4794 -0.0720 0.0494  -0.1179 576 LEU   A CG  
1288 C CD1 . LEU   A 203 ? 0.6043 0.4373 0.4977 -0.0904 0.0518  -0.1090 576 LEU   A CD1 
1289 C CD2 . LEU   A 203 ? 0.5684 0.4782 0.4706 -0.0774 0.0497  -0.1322 576 LEU   A CD2 
1290 N N   . LEU   A 204 ? 0.4617 0.3907 0.3546 -0.0268 0.0469  -0.0740 577 LEU   A N   
1291 C CA  . LEU   A 204 ? 0.4690 0.4006 0.3610 -0.0192 0.0453  -0.0559 577 LEU   A CA  
1292 C C   . LEU   A 204 ? 0.4539 0.3926 0.3451 -0.0246 0.0453  -0.0503 577 LEU   A C   
1293 O O   . LEU   A 204 ? 0.4340 0.4003 0.3280 -0.0271 0.0451  -0.0565 577 LEU   A O   
1294 C CB  . LEU   A 204 ? 0.4779 0.4399 0.3709 -0.0097 0.0444  -0.0519 577 LEU   A CB  
1295 C CG  . LEU   A 204 ? 0.4750 0.4375 0.3687 -0.0037 0.0416  -0.0329 577 LEU   A CG  
1296 C CD1 . LEU   A 204 ? 0.4925 0.4367 0.3896 0.0009  0.0411  -0.0262 577 LEU   A CD1 
1297 C CD2 . LEU   A 204 ? 0.5129 0.5070 0.4052 0.0009  0.0401  -0.0264 577 LEU   A CD2 
1298 N N   . VAL   A 205 ? 0.4526 0.3704 0.3407 -0.0250 0.0448  -0.0397 578 VAL   A N   
1299 C CA  . VAL   A 205 ? 0.4590 0.3871 0.3471 -0.0277 0.0455  -0.0367 578 VAL   A CA  
1300 C C   . VAL   A 205 ? 0.4384 0.3711 0.3278 -0.0162 0.0409  -0.0248 578 VAL   A C   
1301 O O   . VAL   A 205 ? 0.4425 0.3595 0.3306 -0.0110 0.0382  -0.0163 578 VAL   A O   
1302 C CB  . VAL   A 205 ? 0.4890 0.3943 0.3703 -0.0385 0.0493  -0.0357 578 VAL   A CB  
1303 C CG1 . VAL   A 205 ? 0.4903 0.3655 0.3636 -0.0341 0.0463  -0.0243 578 VAL   A CG1 
1304 C CG2 . VAL   A 205 ? 0.5091 0.4344 0.3923 -0.0423 0.0524  -0.0375 578 VAL   A CG2 
1305 N N   . THR   A 206 ? 0.4368 0.3900 0.3304 -0.0126 0.0394  -0.0249 579 THR   A N   
1306 C CA  . THR   A 206 ? 0.4437 0.3985 0.3398 -0.0015 0.0335  -0.0145 579 THR   A CA  
1307 C C   . THR   A 206 ? 0.4279 0.3882 0.3270 0.0013  0.0330  -0.0174 579 THR   A C   
1308 O O   . THR   A 206 ? 0.4539 0.4335 0.3569 -0.0030 0.0368  -0.0275 579 THR   A O   
1309 C CB  . THR   A 206 ? 0.4692 0.4471 0.3686 0.0052  0.0292  -0.0102 579 THR   A CB  
1310 O OG1 . THR   A 206 ? 0.4198 0.4255 0.3241 0.0059  0.0283  -0.0186 579 THR   A OG1 
1311 C CG2 . THR   A 206 ? 0.4966 0.4779 0.3929 0.0024  0.0316  -0.0116 579 THR   A CG2 
1312 N N   . GLY   A 207 ? 0.4351 0.3811 0.3343 0.0095  0.0278  -0.0098 580 GLY   A N   
1313 C CA  . GLY   A 207 ? 0.4333 0.3842 0.3367 0.0168  0.0257  -0.0142 580 GLY   A CA  
1314 C C   . GLY   A 207 ? 0.4441 0.3913 0.3539 0.0299  0.0158  -0.0051 580 GLY   A C   
1315 O O   . GLY   A 207 ? 0.4768 0.4063 0.3846 0.0300  0.0115  0.0065  580 GLY   A O   
1316 N N   . ALA   A 208 ? 0.4873 0.4514 0.4061 0.0404  0.0119  -0.0104 581 ALA   A N   
1317 C CA  . ALA   A 208 ? 0.5054 0.4658 0.4307 0.0538  0.0008  -0.0004 581 ALA   A CA  
1318 C C   . ALA   A 208 ? 0.5130 0.4636 0.4456 0.0669  -0.0047 -0.0073 581 ALA   A C   
1319 O O   . ALA   A 208 ? 0.4740 0.4310 0.4070 0.0661  0.0015  -0.0221 581 ALA   A O   
1320 C CB  . ALA   A 208 ? 0.5237 0.5155 0.4539 0.0583  -0.0021 0.0004  581 ALA   A CB  
1321 N N   . ALA   A 209 ? 0.5226 0.4609 0.4613 0.0795  -0.0167 0.0031  582 ALA   A N   
1322 C CA  . ALA   A 209 ? 0.5561 0.4770 0.5032 0.0946  -0.0252 -0.0026 582 ALA   A CA  
1323 C C   . ALA   A 209 ? 0.5331 0.4860 0.4930 0.1086  -0.0251 -0.0194 582 ALA   A C   
1324 O O   . ALA   A 209 ? 0.5731 0.5200 0.5404 0.1207  -0.0276 -0.0329 582 ALA   A O   
1325 C CB  . ALA   A 209 ? 0.5890 0.4820 0.5384 0.1018  -0.0391 0.0168  582 ALA   A CB  
1326 N N   . ASP   A 210 ? 0.5114 0.5015 0.4749 0.1063  -0.0217 -0.0211 583 ASP   A N   
1327 C CA  . ASP   A 210 ? 0.4813 0.5108 0.4603 0.1174  -0.0208 -0.0381 583 ASP   A CA  
1328 C C   . ASP   A 210 ? 0.4874 0.5395 0.4655 0.1044  -0.0048 -0.0567 583 ASP   A C   
1329 O O   . ASP   A 210 ? 0.5267 0.6192 0.5188 0.1084  -0.0007 -0.0720 583 ASP   A O   
1330 C CB  . ASP   A 210 ? 0.4808 0.5433 0.4656 0.1206  -0.0265 -0.0323 583 ASP   A CB  
1331 C CG  . ASP   A 210 ? 0.4879 0.5668 0.4620 0.1000  -0.0176 -0.0294 583 ASP   A CG  
1332 O OD1 . ASP   A 210 ? 0.4745 0.5334 0.4362 0.0835  -0.0077 -0.0285 583 ASP   A OD1 
1333 O OD2 . ASP   A 210 ? 0.5095 0.6211 0.4880 0.1017  -0.0220 -0.0290 583 ASP   A OD2 
1334 N N   . GLY   A 211 ? 0.4766 0.5046 0.4388 0.0884  0.0038  -0.0547 584 GLY   A N   
1335 C CA  . GLY   A 211 ? 0.4960 0.5399 0.4527 0.0741  0.0185  -0.0677 584 GLY   A CA  
1336 C C   . GLY   A 211 ? 0.5095 0.5766 0.4641 0.0555  0.0273  -0.0674 584 GLY   A C   
1337 O O   . GLY   A 211 ? 0.4923 0.5747 0.4438 0.0415  0.0394  -0.0765 584 GLY   A O   
1338 N N   . VAL   A 212 ? 0.4937 0.5624 0.4489 0.0544  0.0213  -0.0571 585 VAL   A N   
1339 C CA  . VAL   A 212 ? 0.4726 0.5654 0.4286 0.0390  0.0274  -0.0608 585 VAL   A CA  
1340 C C   . VAL   A 212 ? 0.4604 0.5233 0.3997 0.0236  0.0317  -0.0516 585 VAL   A C   
1341 O O   . VAL   A 212 ? 0.4517 0.4863 0.3828 0.0280  0.0261  -0.0388 585 VAL   A O   
1342 C CB  . VAL   A 212 ? 0.4641 0.5867 0.4312 0.0476  0.0181  -0.0600 585 VAL   A CB  
1343 C CG1 . VAL   A 212 ? 0.4582 0.6033 0.4251 0.0300  0.0238  -0.0667 585 VAL   A CG1 
1344 C CG2 . VAL   A 212 ? 0.4430 0.5990 0.4299 0.0654  0.0119  -0.0698 585 VAL   A CG2 
1345 N N   . ILE   A 213 ? 0.4682 0.5380 0.4042 0.0051  0.0415  -0.0585 586 ILE   A N   
1346 C CA  . ILE   A 213 ? 0.4461 0.4896 0.3693 -0.0076 0.0444  -0.0524 586 ILE   A CA  
1347 C C   . ILE   A 213 ? 0.4513 0.5158 0.3795 -0.0123 0.0424  -0.0572 586 ILE   A C   
1348 O O   . ILE   A 213 ? 0.4585 0.5553 0.3976 -0.0183 0.0445  -0.0687 586 ILE   A O   
1349 C CB  . ILE   A 213 ? 0.4348 0.4624 0.3483 -0.0248 0.0547  -0.0549 586 ILE   A CB  
1350 C CG1 . ILE   A 213 ? 0.4461 0.4504 0.3491 -0.0199 0.0553  -0.0493 586 ILE   A CG1 
1351 C CG2 . ILE   A 213 ? 0.4303 0.4343 0.3350 -0.0369 0.0563  -0.0518 586 ILE   A CG2 
1352 C CD1 . ILE   A 213 ? 0.4685 0.4552 0.3568 -0.0363 0.0640  -0.0478 586 ILE   A CD1 
1353 N N   . ARG   A 214 ? 0.4347 0.4840 0.3556 -0.0096 0.0383  -0.0495 587 ARG   A N   
1354 C CA  . ARG   A 214 ? 0.4323 0.5005 0.3543 -0.0133 0.0362  -0.0554 587 ARG   A CA  
1355 C C   . ARG   A 214 ? 0.4336 0.4751 0.3463 -0.0235 0.0408  -0.0566 587 ARG   A C   
1356 O O   . ARG   A 214 ? 0.4314 0.4466 0.3368 -0.0188 0.0402  -0.0464 587 ARG   A O   
1357 C CB  . ARG   A 214 ? 0.4240 0.5055 0.3452 0.0018  0.0268  -0.0456 587 ARG   A CB  
1358 C CG  . ARG   A 214 ? 0.4023 0.5102 0.3345 0.0145  0.0196  -0.0452 587 ARG   A CG  
1359 C CD  . ARG   A 214 ? 0.3953 0.5073 0.3237 0.0292  0.0089  -0.0304 587 ARG   A CD  
1360 N NE  . ARG   A 214 ? 0.4153 0.5466 0.3549 0.0446  -0.0003 -0.0287 587 ARG   A NE  
1361 C CZ  . ARG   A 214 ? 0.4574 0.5733 0.4039 0.0546  -0.0025 -0.0261 587 ARG   A CZ  
1362 N NH1 . ARG   A 214 ? 0.4699 0.5487 0.4098 0.0515  0.0019  -0.0203 587 ARG   A NH1 
1363 N NH2 . ARG   A 214 ? 0.4597 0.5976 0.4200 0.0696  -0.0106 -0.0297 587 ARG   A NH2 
1364 N N   . LEU   A 215 ? 0.4674 0.5165 0.3825 -0.0372 0.0444  -0.0704 588 LEU   A N   
1365 C CA  . LEU   A 215 ? 0.4857 0.5075 0.3941 -0.0455 0.0474  -0.0745 588 LEU   A CA  
1366 C C   . LEU   A 215 ? 0.4952 0.5369 0.4037 -0.0443 0.0441  -0.0857 588 LEU   A C   
1367 O O   . LEU   A 215 ? 0.5206 0.5939 0.4357 -0.0495 0.0421  -0.0977 588 LEU   A O   
1368 C CB  . LEU   A 215 ? 0.5109 0.5158 0.4199 -0.0638 0.0538  -0.0812 588 LEU   A CB  
1369 C CG  . LEU   A 215 ? 0.5787 0.5513 0.4826 -0.0723 0.0550  -0.0873 588 LEU   A CG  
1370 C CD1 . LEU   A 215 ? 0.5734 0.5054 0.4677 -0.0673 0.0552  -0.0741 588 LEU   A CD1 
1371 C CD2 . LEU   A 215 ? 0.6496 0.6191 0.5582 -0.0940 0.0593  -0.0985 588 LEU   A CD2 
1372 N N   . PHE   A 216 ? 0.4934 0.5192 0.3950 -0.0378 0.0437  -0.0831 589 PHE   A N   
1373 C CA  . PHE   A 216 ? 0.5098 0.5588 0.4082 -0.0332 0.0412  -0.0924 589 PHE   A CA  
1374 C C   . PHE   A 216 ? 0.4800 0.5082 0.3771 -0.0393 0.0440  -0.1082 589 PHE   A C   
1375 O O   . PHE   A 216 ? 0.4895 0.4834 0.3856 -0.0380 0.0462  -0.1041 589 PHE   A O   
1376 C CB  . PHE   A 216 ? 0.4994 0.5566 0.3915 -0.0192 0.0392  -0.0778 589 PHE   A CB  
1377 C CG  . PHE   A 216 ? 0.4703 0.5482 0.3632 -0.0116 0.0339  -0.0633 589 PHE   A CG  
1378 C CD1 . PHE   A 216 ? 0.5128 0.6285 0.4036 -0.0082 0.0284  -0.0663 589 PHE   A CD1 
1379 C CD2 . PHE   A 216 ? 0.4638 0.5225 0.3595 -0.0074 0.0331  -0.0483 589 PHE   A CD2 
1380 C CE1 . PHE   A 216 ? 0.5146 0.6456 0.4071 0.0008  0.0215  -0.0525 589 PHE   A CE1 
1381 C CE2 . PHE   A 216 ? 0.4732 0.5465 0.3715 0.0010  0.0270  -0.0374 589 PHE   A CE2 
1382 C CZ  . PHE   A 216 ? 0.5042 0.6119 0.4014 0.0059  0.0209  -0.0386 589 PHE   A CZ  
1383 N N   . ASP   A 217 ? 0.4919 0.5422 0.3899 -0.0448 0.0423  -0.1274 590 ASP   A N   
1384 C CA  . ASP   A 217 ? 0.5227 0.5585 0.4195 -0.0476 0.0433  -0.1468 590 ASP   A CA  
1385 C C   . ASP   A 217 ? 0.5209 0.5753 0.4100 -0.0327 0.0437  -0.1466 590 ASP   A C   
1386 O O   . ASP   A 217 ? 0.5217 0.6161 0.4047 -0.0282 0.0412  -0.1474 590 ASP   A O   
1387 C CB  . ASP   A 217 ? 0.5330 0.5844 0.4349 -0.0622 0.0409  -0.1690 590 ASP   A CB  
1388 C CG  . ASP   A 217 ? 0.5788 0.6204 0.4798 -0.0649 0.0402  -0.1947 590 ASP   A CG  
1389 O OD1 . ASP   A 217 ? 0.5862 0.6141 0.4826 -0.0525 0.0420  -0.1964 590 ASP   A OD1 
1390 O OD2 . ASP   A 217 ? 0.6810 0.7331 0.5871 -0.0787 0.0373  -0.2145 590 ASP   A OD2 
1391 N N   . MET   A 218 ? 0.5306 0.5582 0.4203 -0.0253 0.0467  -0.1446 591 MET   A N   
1392 C CA  . MET   A 218 ? 0.5461 0.5933 0.4312 -0.0118 0.0491  -0.1413 591 MET   A CA  
1393 C C   . MET   A 218 ? 0.5961 0.6587 0.4786 -0.0088 0.0505  -0.1684 591 MET   A C   
1394 O O   . MET   A 218 ? 0.6099 0.6909 0.4895 0.0020  0.0543  -0.1703 591 MET   A O   
1395 C CB  . MET   A 218 ? 0.5351 0.5524 0.4257 -0.0044 0.0512  -0.1273 591 MET   A CB  
1396 C CG  . MET   A 218 ? 0.5402 0.5425 0.4319 -0.0071 0.0494  -0.1030 591 MET   A CG  
1397 S SD  . MET   A 218 ? 0.5180 0.5580 0.4039 -0.0039 0.0475  -0.0834 591 MET   A SD  
1398 C CE  . MET   A 218 ? 0.5329 0.5829 0.4195 0.0065  0.0513  -0.0747 591 MET   A CE  
1399 N N   . GLN   A 219 ? 0.6324 0.6909 0.5163 -0.0191 0.0475  -0.1906 592 GLN   A N   
1400 C CA  . GLN   A 219 ? 0.7023 0.7771 0.5827 -0.0166 0.0476  -0.2207 592 GLN   A CA  
1401 C C   . GLN   A 219 ? 0.6413 0.7679 0.5110 -0.0203 0.0443  -0.2277 592 GLN   A C   
1402 O O   . GLN   A 219 ? 0.6454 0.8087 0.5040 -0.0120 0.0461  -0.2370 592 GLN   A O   
1403 C CB  . GLN   A 219 ? 0.7921 0.8247 0.6816 -0.0256 0.0450  -0.2446 592 GLN   A CB  
1404 C CG  . GLN   A 219 ? 0.8867 0.8699 0.7845 -0.0172 0.0464  -0.2422 592 GLN   A CG  
1405 C CD  . GLN   A 219 ? 1.0139 0.9482 0.9196 -0.0263 0.0421  -0.2631 592 GLN   A CD  
1406 O OE1 . GLN   A 219 ? 0.9774 0.8818 0.8864 -0.0434 0.0396  -0.2558 592 GLN   A OE1 
1407 N NE2 . GLN   A 219 ? 1.0922 1.0174 1.0012 -0.0153 0.0414  -0.2899 592 GLN   A NE2 
1408 N N   . GLN   A 220 ? 0.5981 0.7297 0.4713 -0.0324 0.0393  -0.2231 593 GLN   A N   
1409 C CA  . GLN   A 220 ? 0.6323 0.8131 0.4977 -0.0351 0.0336  -0.2263 593 GLN   A CA  
1410 C C   . GLN   A 220 ? 0.6239 0.8314 0.4807 -0.0251 0.0327  -0.1956 593 GLN   A C   
1411 O O   . GLN   A 220 ? 0.6039 0.8548 0.4507 -0.0229 0.0269  -0.1940 593 GLN   A O   
1412 C CB  . GLN   A 220 ? 0.7132 0.8884 0.5913 -0.0516 0.0287  -0.2324 593 GLN   A CB  
1413 C CG  . GLN   A 220 ? 0.8456 0.9934 0.7325 -0.0659 0.0280  -0.2620 593 GLN   A CG  
1414 C CD  . GLN   A 220 ? 0.9367 1.1227 0.8185 -0.0708 0.0217  -0.2923 593 GLN   A CD  
1415 O OE1 . GLN   A 220 ? 0.9768 1.1884 0.8445 -0.0592 0.0219  -0.3038 593 GLN   A OE1 
1416 N NE2 . GLN   A 220 ? 0.9928 1.1882 0.8860 -0.0888 0.0162  -0.3056 593 GLN   A NE2 
1417 N N   . HIS   A 221 ? 0.5709 0.7504 0.4321 -0.0197 0.0369  -0.1711 594 HIS   A N   
1418 C CA  . HIS   A 221 ? 0.5472 0.7411 0.4030 -0.0117 0.0354  -0.1413 594 HIS   A CA  
1419 C C   . HIS   A 221 ? 0.5681 0.7807 0.4274 -0.0150 0.0273  -0.1343 594 HIS   A C   
1420 O O   . HIS   A 221 ? 0.5501 0.7980 0.3994 -0.0089 0.0212  -0.1244 594 HIS   A O   
1421 C CB  . HIS   A 221 ? 0.5218 0.7503 0.3610 -0.0027 0.0374  -0.1354 594 HIS   A CB  
1422 C CG  . HIS   A 221 ? 0.4903 0.7109 0.3287 0.0018  0.0460  -0.1466 594 HIS   A CG  
1423 N ND1 . HIS   A 221 ? 0.4867 0.6768 0.3346 0.0057  0.0514  -0.1332 594 HIS   A ND1 
1424 C CD2 . HIS   A 221 ? 0.5023 0.7439 0.3333 0.0045  0.0498  -0.1704 594 HIS   A CD2 
1425 C CE1 . HIS   A 221 ? 0.4819 0.6758 0.3304 0.0114  0.0579  -0.1486 594 HIS   A CE1 
1426 N NE2 . HIS   A 221 ? 0.5243 0.7489 0.3623 0.0113  0.0577  -0.1720 594 HIS   A NE2 
1427 N N   . GLU   A 222 ? 0.6024 0.7927 0.4761 -0.0240 0.0272  -0.1384 595 GLU   A N   
1428 C CA  . GLU   A 222 ? 0.6076 0.8174 0.4894 -0.0257 0.0207  -0.1325 595 GLU   A CA  
1429 C C   . GLU   A 222 ? 0.5347 0.7116 0.4296 -0.0311 0.0248  -0.1244 595 GLU   A C   
1430 O O   . GLU   A 222 ? 0.5439 0.6826 0.4402 -0.0362 0.0313  -0.1256 595 GLU   A O   
1431 C CB  . GLU   A 222 ? 0.6372 0.8799 0.5240 -0.0355 0.0151  -0.1562 595 GLU   A CB  
1432 C CG  . GLU   A 222 ? 0.7195 0.9376 0.6159 -0.0525 0.0198  -0.1798 595 GLU   A CG  
1433 C CD  . GLU   A 222 ? 0.8313 1.0832 0.7316 -0.0639 0.0134  -0.2070 595 GLU   A CD  
1434 O OE1 . GLU   A 222 ? 0.8764 1.1753 0.7732 -0.0579 0.0046  -0.2069 595 GLU   A OE1 
1435 O OE2 . GLU   A 222 ? 0.8835 1.1136 0.7900 -0.0785 0.0161  -0.2283 595 GLU   A OE2 
1436 N N   . CYS   A 223 ? 0.5045 0.6988 0.4079 -0.0284 0.0202  -0.1162 596 CYS   A N   
1437 C CA  . CYS   A 223 ? 0.5210 0.6951 0.4361 -0.0335 0.0243  -0.1111 596 CYS   A CA  
1438 C C   . CYS   A 223 ? 0.4963 0.6719 0.4224 -0.0527 0.0281  -0.1311 596 CYS   A C   
1439 O O   . CYS   A 223 ? 0.4878 0.7005 0.4226 -0.0580 0.0232  -0.1443 596 CYS   A O   
1440 C CB  . CYS   A 223 ? 0.5001 0.6963 0.4228 -0.0220 0.0182  -0.0991 596 CYS   A CB  
1441 S SG  . CYS   A 223 ? 0.5039 0.6770 0.4380 -0.0256 0.0250  -0.0936 596 CYS   A SG  
1442 N N   . ALA   A 224 ? 0.5111 0.6459 0.4366 -0.0640 0.0358  -0.1327 597 ALA   A N   
1443 C CA  . ALA   A 224 ? 0.5118 0.6410 0.4467 -0.0857 0.0397  -0.1488 597 ALA   A CA  
1444 C C   . ALA   A 224 ? 0.5043 0.6490 0.4521 -0.0936 0.0433  -0.1450 597 ALA   A C   
1445 O O   . ALA   A 224 ? 0.4979 0.6603 0.4579 -0.1114 0.0451  -0.1585 597 ALA   A O   
1446 C CB  . ALA   A 224 ? 0.5196 0.5972 0.4476 -0.0939 0.0450  -0.1496 597 ALA   A CB  
1447 N N   . MET   A 225 ? 0.5249 0.6678 0.4711 -0.0799 0.0441  -0.1280 598 MET   A N   
1448 C CA  . MET   A 225 ? 0.5360 0.6842 0.4909 -0.0861 0.0503  -0.1242 598 MET   A CA  
1449 C C   . MET   A 225 ? 0.4788 0.6269 0.4309 -0.0649 0.0475  -0.1087 598 MET   A C   
1450 O O   . MET   A 225 ? 0.4503 0.5679 0.3896 -0.0539 0.0459  -0.0960 598 MET   A O   
1451 C CB  . MET   A 225 ? 0.6567 0.7599 0.6031 -0.1024 0.0593  -0.1198 598 MET   A CB  
1452 C CG  . MET   A 225 ? 0.7468 0.8596 0.7019 -0.1227 0.0682  -0.1233 598 MET   A CG  
1453 S SD  . MET   A 225 ? 0.8269 0.8786 0.7665 -0.1430 0.0754  -0.1159 598 MET   A SD  
1454 C CE  . MET   A 225 ? 0.9229 0.9682 0.8682 -0.1560 0.0702  -0.1349 598 MET   A CE  
1455 N N   . SER   A 226 ? 0.4954 0.6756 0.4609 -0.0600 0.0475  -0.1107 599 SER   A N   
1456 C CA  . SER   A 226 ? 0.4890 0.6618 0.4528 -0.0419 0.0459  -0.0987 599 SER   A CA  
1457 C C   . SER   A 226 ? 0.4530 0.6548 0.4318 -0.0446 0.0519  -0.1064 599 SER   A C   
1458 O O   . SER   A 226 ? 0.4443 0.6858 0.4393 -0.0547 0.0535  -0.1199 599 SER   A O   
1459 C CB  . SER   A 226 ? 0.4565 0.6432 0.4212 -0.0196 0.0335  -0.0914 599 SER   A CB  
1460 O OG  . SER   A 226 ? 0.4602 0.6961 0.4409 -0.0168 0.0273  -0.1026 599 SER   A OG  
1461 N N   . TRP   A 227 ? 0.4528 0.6397 0.4277 -0.0332 0.0538  -0.0991 600 TRP   A N   
1462 C CA  . TRP   A 227 ? 0.4889 0.7034 0.4759 -0.0333 0.0609  -0.1076 600 TRP   A CA  
1463 C C   . TRP   A 227 ? 0.5027 0.6982 0.4843 -0.0129 0.0579  -0.1008 600 TRP   A C   
1464 O O   . TRP   A 227 ? 0.5106 0.6639 0.4759 -0.0074 0.0541  -0.0881 600 TRP   A O   
1465 C CB  . TRP   A 227 ? 0.4765 0.6848 0.4576 -0.0605 0.0756  -0.1108 600 TRP   A CB  
1466 C CG  . TRP   A 227 ? 0.4611 0.6158 0.4174 -0.0667 0.0799  -0.0975 600 TRP   A CG  
1467 C CD1 . TRP   A 227 ? 0.4893 0.6295 0.4345 -0.0626 0.0850  -0.0927 600 TRP   A CD1 
1468 C CD2 . TRP   A 227 ? 0.4539 0.5658 0.3944 -0.0771 0.0787  -0.0888 600 TRP   A CD2 
1469 N NE1 . TRP   A 227 ? 0.5011 0.5935 0.4242 -0.0701 0.0861  -0.0802 600 TRP   A NE1 
1470 C CE2 . TRP   A 227 ? 0.4758 0.5495 0.3970 -0.0780 0.0822  -0.0774 600 TRP   A CE2 
1471 C CE3 . TRP   A 227 ? 0.4887 0.5917 0.4296 -0.0844 0.0745  -0.0913 600 TRP   A CE3 
1472 C CZ2 . TRP   A 227 ? 0.4802 0.5085 0.3850 -0.0843 0.0806  -0.0673 600 TRP   A CZ2 
1473 C CZ3 . TRP   A 227 ? 0.4706 0.5277 0.3955 -0.0900 0.0740  -0.0831 600 TRP   A CZ3 
1474 C CH2 . TRP   A 227 ? 0.4794 0.4998 0.3876 -0.0897 0.0768  -0.0707 600 TRP   A CH2 
1475 N N   . ARG   A 228 ? 0.5211 0.7496 0.5178 -0.0035 0.0605  -0.1115 601 ARG   A N   
1476 C CA  . ARG   A 228 ? 0.5766 0.7907 0.5704 0.0148  0.0587  -0.1107 601 ARG   A CA  
1477 C C   . ARG   A 228 ? 0.5344 0.7223 0.5082 -0.0004 0.0710  -0.1081 601 ARG   A C   
1478 O O   . ARG   A 228 ? 0.5233 0.7333 0.4975 -0.0190 0.0843  -0.1151 601 ARG   A O   
1479 C CB  . ARG   A 228 ? 0.6730 0.9382 0.6930 0.0311  0.0570  -0.1269 601 ARG   A CB  
1480 C CG  . ARG   A 228 ? 0.8394 1.0958 0.8617 0.0544  0.0536  -0.1320 601 ARG   A CG  
1481 C CD  . ARG   A 228 ? 0.9637 1.1922 0.9880 0.0804  0.0351  -0.1221 601 ARG   A CD  
1482 N NE  . ARG   A 228 ? 1.0904 1.2954 1.1113 0.0967  0.0332  -0.1270 601 ARG   A NE  
1483 C CZ  . ARG   A 228 ? 1.1546 1.3769 1.1943 0.1221  0.0265  -0.1404 601 ARG   A CZ  
1484 N NH1 . ARG   A 228 ? 1.2347 1.4361 1.2690 0.1327  0.0274  -0.1489 601 ARG   A NH1 
1485 N NH2 . ARG   A 228 ? 1.1467 1.4088 1.2111 0.1375  0.0184  -0.1471 601 ARG   A NH2 
1486 N N   . ALA   A 229 ? 0.5168 0.6589 0.4727 0.0063  0.0661  -0.0968 602 ALA   A N   
1487 C CA  . ALA   A 229 ? 0.5147 0.6280 0.4482 -0.0080 0.0746  -0.0911 602 ALA   A CA  
1488 C C   . ALA   A 229 ? 0.5184 0.6274 0.4458 0.0044  0.0756  -0.0975 602 ALA   A C   
1489 O O   . ALA   A 229 ? 0.4954 0.6032 0.4072 -0.0079 0.0860  -0.0990 602 ALA   A O   
1490 C CB  . ALA   A 229 ? 0.5108 0.5786 0.4285 -0.0124 0.0685  -0.0753 602 ALA   A CB  
1491 N N   . HIS   A 230 ? 0.4899 0.5896 0.4260 0.0278  0.0636  -0.0993 603 HIS   A N   
1492 C CA  . HIS   A 230 ? 0.5252 0.6137 0.4558 0.0415  0.0616  -0.1074 603 HIS   A CA  
1493 C C   . HIS   A 230 ? 0.5446 0.6536 0.4989 0.0674  0.0529  -0.1201 603 HIS   A C   
1494 O O   . HIS   A 230 ? 0.4983 0.6162 0.4687 0.0767  0.0438  -0.1157 603 HIS   A O   
1495 C CB  . HIS   A 230 ? 0.5209 0.5584 0.4339 0.0423  0.0529  -0.0942 603 HIS   A CB  
1496 C CG  . HIS   A 230 ? 0.5421 0.5593 0.4322 0.0213  0.0598  -0.0834 603 HIS   A CG  
1497 N ND1 . HIS   A 230 ? 0.5585 0.5698 0.4284 0.0139  0.0665  -0.0868 603 HIS   A ND1 
1498 C CD2 . HIS   A 230 ? 0.5262 0.5272 0.4099 0.0074  0.0601  -0.0695 603 HIS   A CD2 
1499 C CE1 . HIS   A 230 ? 0.5452 0.5363 0.3974 -0.0038 0.0698  -0.0731 603 HIS   A CE1 
1500 N NE2 . HIS   A 230 ? 0.5195 0.5021 0.3809 -0.0069 0.0657  -0.0634 603 HIS   A NE2 
1501 N N   . TYR   A 231 ? 0.5812 0.7010 0.5369 0.0791  0.0559  -0.1370 604 TYR   A N   
1502 C CA  . TYR   A 231 ? 0.6675 0.7887 0.6422 0.1078  0.0440  -0.1490 604 TYR   A CA  
1503 C C   . TYR   A 231 ? 0.6295 0.6934 0.5934 0.1157  0.0298  -0.1380 604 TYR   A C   
1504 O O   . TYR   A 231 ? 0.6726 0.7138 0.6190 0.1117  0.0317  -0.1420 604 TYR   A O   
1505 C CB  . TYR   A 231 ? 0.7508 0.9088 0.7323 0.1177  0.0538  -0.1752 604 TYR   A CB  
1506 C CG  . TYR   A 231 ? 0.9761 1.1397 0.9821 0.1509  0.0412  -0.1917 604 TYR   A CG  
1507 C CD1 . TYR   A 231 ? 1.1161 1.3134 1.1508 0.1663  0.0347  -0.1954 604 TYR   A CD1 
1508 C CD2 . TYR   A 231 ? 1.0499 1.1842 1.0509 0.1677  0.0343  -0.2045 604 TYR   A CD2 
1509 C CE1 . TYR   A 231 ? 1.1493 1.3490 1.2074 0.1991  0.0212  -0.2095 604 TYR   A CE1 
1510 C CE2 . TYR   A 231 ? 1.0887 1.2222 1.1132 0.1994  0.0212  -0.2203 604 TYR   A CE2 
1511 C CZ  . TYR   A 231 ? 1.1775 1.3428 1.2307 0.2160  0.0145  -0.2219 604 TYR   A CZ  
1512 O OH  . TYR   A 231 ? 1.3055 1.4681 1.3829 0.2496  0.0000  -0.2365 604 TYR   A OH  
1513 N N   . GLY   A 232 ? 0.5684 0.6114 0.5415 0.1242  0.0157  -0.1229 605 GLY   A N   
1514 C CA  . GLY   A 232 ? 0.5586 0.5496 0.5231 0.1263  0.0029  -0.1080 605 GLY   A CA  
1515 C C   . GLY   A 232 ? 0.5583 0.5339 0.5090 0.1055  0.0051  -0.0862 605 GLY   A C   
1516 O O   . GLY   A 232 ? 0.5671 0.5686 0.5158 0.0920  0.0147  -0.0837 605 GLY   A O   
1517 N N   . GLU   A 233 ? 0.5722 0.5065 0.5137 0.1020  -0.0028 -0.0732 606 GLU   A N   
1518 C CA  . GLU   A 233 ? 0.5721 0.4924 0.5047 0.0866  -0.0027 -0.0532 606 GLU   A CA  
1519 C C   . GLU   A 233 ? 0.5676 0.4943 0.4841 0.0674  0.0100  -0.0539 606 GLU   A C   
1520 O O   . GLU   A 233 ? 0.5475 0.4737 0.4534 0.0638  0.0158  -0.0646 606 GLU   A O   
1521 C CB  . GLU   A 233 ? 0.6137 0.4926 0.5437 0.0871  -0.0141 -0.0405 606 GLU   A CB  
1522 C CG  . GLU   A 233 ? 0.6443 0.5066 0.5886 0.1047  -0.0285 -0.0366 606 GLU   A CG  
1523 C CD  . GLU   A 233 ? 0.6740 0.4986 0.6170 0.0991  -0.0388 -0.0176 606 GLU   A CD  
1524 O OE1 . GLU   A 233 ? 0.6731 0.5000 0.6104 0.0856  -0.0355 -0.0011 606 GLU   A OE1 
1525 O OE2 . GLU   A 233 ? 0.7699 0.5640 0.7184 0.1075  -0.0497 -0.0204 606 GLU   A OE2 
1526 N N   . VAL   A 234 ? 0.5334 0.4625 0.4466 0.0557  0.0128  -0.0412 607 VAL   A N   
1527 C CA  . VAL   A 234 ? 0.4793 0.4012 0.3777 0.0389  0.0207  -0.0369 607 VAL   A CA  
1528 C C   . VAL   A 234 ? 0.4889 0.3790 0.3817 0.0362  0.0133  -0.0243 607 VAL   A C   
1529 O O   . VAL   A 234 ? 0.5061 0.3890 0.4068 0.0403  0.0062  -0.0137 607 VAL   A O   
1530 C CB  . VAL   A 234 ? 0.4659 0.4080 0.3664 0.0289  0.0273  -0.0341 607 VAL   A CB  
1531 C CG1 . VAL   A 234 ? 0.4693 0.4016 0.3554 0.0125  0.0352  -0.0317 607 VAL   A CG1 
1532 C CG2 . VAL   A 234 ? 0.4576 0.4369 0.3702 0.0325  0.0317  -0.0461 607 VAL   A CG2 
1533 N N   . TYR   A 235 ? 0.5084 0.3828 0.3874 0.0285  0.0151  -0.0247 608 TYR   A N   
1534 C CA  . TYR   A 235 ? 0.5382 0.3870 0.4146 0.0266  0.0070  -0.0155 608 TYR   A CA  
1535 C C   . TYR   A 235 ? 0.5272 0.3710 0.3973 0.0160  0.0100  -0.0059 608 TYR   A C   
1536 O O   . TYR   A 235 ? 0.5571 0.3903 0.4326 0.0151  0.0044  0.0036  608 TYR   A O   
1537 C CB  . TYR   A 235 ? 0.5951 0.4311 0.4613 0.0285  0.0036  -0.0249 608 TYR   A CB  
1538 C CG  . TYR   A 235 ? 0.6225 0.4569 0.4968 0.0415  -0.0018 -0.0368 608 TYR   A CG  
1539 C CD1 . TYR   A 235 ? 0.6220 0.4483 0.5129 0.0507  -0.0104 -0.0314 608 TYR   A CD1 
1540 C CD2 . TYR   A 235 ? 0.6804 0.5186 0.5444 0.0451  0.0003  -0.0532 608 TYR   A CD2 
1541 C CE1 . TYR   A 235 ? 0.6523 0.4695 0.5515 0.0644  -0.0179 -0.0425 608 TYR   A CE1 
1542 C CE2 . TYR   A 235 ? 0.7456 0.5797 0.6182 0.0594  -0.0057 -0.0676 608 TYR   A CE2 
1543 C CZ  . TYR   A 235 ? 0.7013 0.5223 0.5926 0.0697  -0.0157 -0.0623 608 TYR   A CZ  
1544 O OH  . TYR   A 235 ? 0.7609 0.5733 0.6617 0.0856  -0.0232 -0.0770 608 TYR   A OH  
1545 N N   . SER   A 236 ? 0.5344 0.3842 0.3931 0.0080  0.0184  -0.0090 609 SER   A N   
1546 C CA  . SER   A 236 ? 0.5187 0.3597 0.3720 0.0000  0.0202  -0.0014 609 SER   A CA  
1547 C C   . SER   A 236 ? 0.5250 0.3777 0.3739 -0.0085 0.0302  -0.0052 609 SER   A C   
1548 O O   . SER   A 236 ? 0.5344 0.4008 0.3790 -0.0115 0.0366  -0.0129 609 SER   A O   
1549 C CB  . SER   A 236 ? 0.5578 0.3791 0.3976 -0.0027 0.0153  0.0024  609 SER   A CB  
1550 O OG  . SER   A 236 ? 0.5992 0.4107 0.4456 0.0026  0.0052  0.0051  609 SER   A OG  
1551 N N   . VAL   A 237 ? 0.5318 0.3796 0.3831 -0.0127 0.0313  -0.0009 610 VAL   A N   
1552 C CA  . VAL   A 237 ? 0.5574 0.4102 0.4064 -0.0228 0.0390  -0.0045 610 VAL   A CA  
1553 C C   . VAL   A 237 ? 0.5642 0.3933 0.4079 -0.0262 0.0367  0.0014  610 VAL   A C   
1554 O O   . VAL   A 237 ? 0.5339 0.3557 0.3837 -0.0186 0.0304  0.0061  610 VAL   A O   
1555 C CB  . VAL   A 237 ? 0.5441 0.4211 0.4073 -0.0211 0.0413  -0.0107 610 VAL   A CB  
1556 C CG1 . VAL   A 237 ? 0.5532 0.4553 0.4232 -0.0167 0.0429  -0.0175 610 VAL   A CG1 
1557 C CG2 . VAL   A 237 ? 0.5485 0.4261 0.4208 -0.0127 0.0356  -0.0058 610 VAL   A CG2 
1558 N N   . GLU   A 238 ? 0.5619 0.3795 0.3959 -0.0378 0.0417  0.0013  611 GLU   A N   
1559 C CA  . GLU   A 238 ? 0.6148 0.4058 0.4450 -0.0393 0.0382  0.0063  611 GLU   A CA  
1560 C C   . GLU   A 238 ? 0.6239 0.4069 0.4501 -0.0539 0.0448  0.0028  611 GLU   A C   
1561 O O   . GLU   A 238 ? 0.6375 0.4314 0.4573 -0.0658 0.0521  0.0011  611 GLU   A O   
1562 C CB  . GLU   A 238 ? 0.7011 0.4690 0.5168 -0.0364 0.0312  0.0171  611 GLU   A CB  
1563 C CG  . GLU   A 238 ? 0.8298 0.5685 0.6434 -0.0341 0.0249  0.0230  611 GLU   A CG  
1564 C CD  . GLU   A 238 ? 0.9674 0.7126 0.8010 -0.0219 0.0208  0.0178  611 GLU   A CD  
1565 O OE1 . GLU   A 238 ? 0.9425 0.6955 0.7820 -0.0126 0.0147  0.0213  611 GLU   A OE1 
1566 O OE2 . GLU   A 238 ? 0.8246 0.5715 0.6685 -0.0223 0.0242  0.0090  611 GLU   A OE2 
1567 N N   . PHE   A 239 ? 0.6053 0.3699 0.4366 -0.0532 0.0420  0.0005  612 PHE   A N   
1568 C CA  . PHE   A 239 ? 0.6112 0.3542 0.4372 -0.0678 0.0453  -0.0008 612 PHE   A CA  
1569 C C   . PHE   A 239 ? 0.6618 0.3698 0.4676 -0.0740 0.0421  0.0144  612 PHE   A C   
1570 O O   . PHE   A 239 ? 0.6908 0.3836 0.4915 -0.0619 0.0335  0.0230  612 PHE   A O   
1571 C CB  . PHE   A 239 ? 0.6082 0.3403 0.4467 -0.0621 0.0419  -0.0109 612 PHE   A CB  
1572 C CG  . PHE   A 239 ? 0.5710 0.3390 0.4247 -0.0605 0.0458  -0.0262 612 PHE   A CG  
1573 C CD1 . PHE   A 239 ? 0.5514 0.3451 0.4145 -0.0455 0.0436  -0.0283 612 PHE   A CD1 
1574 C CD2 . PHE   A 239 ? 0.5520 0.3293 0.4096 -0.0754 0.0512  -0.0372 612 PHE   A CD2 
1575 C CE1 . PHE   A 239 ? 0.5481 0.3751 0.4211 -0.0441 0.0462  -0.0397 612 PHE   A CE1 
1576 C CE2 . PHE   A 239 ? 0.5541 0.3677 0.4238 -0.0733 0.0531  -0.0507 612 PHE   A CE2 
1577 C CZ  . PHE   A 239 ? 0.5209 0.3585 0.3966 -0.0569 0.0503  -0.0512 612 PHE   A CZ  
1578 N N   . SER   A 240 ? 0.6655 0.3653 0.4592 -0.0938 0.0490  0.0187  613 SER   A N   
1579 C CA  . SER   A 240 ? 0.7034 0.3629 0.4762 -0.1033 0.0458  0.0348  613 SER   A CA  
1580 C C   . SER   A 240 ? 0.7534 0.3740 0.5326 -0.0948 0.0358  0.0348  613 SER   A C   
1581 O O   . SER   A 240 ? 0.7272 0.3528 0.5251 -0.0905 0.0359  0.0196  613 SER   A O   
1582 C CB  . SER   A 240 ? 0.6933 0.3515 0.4553 -0.1297 0.0563  0.0389  613 SER   A CB  
1583 O OG  . SER   A 240 ? 0.6831 0.3301 0.4588 -0.1412 0.0584  0.0288  613 SER   A OG  
1584 N N   . TYR   A 241 ? 0.8208 0.4023 0.5828 -0.0931 0.0272  0.0516  614 TYR   A N   
1585 C CA  . TYR   A 241 ? 0.8419 0.3816 0.6093 -0.0836 0.0163  0.0526  614 TYR   A CA  
1586 C C   . TYR   A 241 ? 0.8261 0.3475 0.6028 -0.0982 0.0207  0.0415  614 TYR   A C   
1587 O O   . TYR   A 241 ? 0.8353 0.3442 0.6291 -0.0860 0.0152  0.0277  614 TYR   A O   
1588 C CB  . TYR   A 241 ? 0.9116 0.4117 0.6544 -0.0831 0.0061  0.0762  614 TYR   A CB  
1589 C CG  . TYR   A 241 ? 1.0138 0.4684 0.7636 -0.0681 -0.0080 0.0780  614 TYR   A CG  
1590 C CD1 . TYR   A 241 ? 1.0371 0.5026 0.8073 -0.0417 -0.0171 0.0678  614 TYR   A CD1 
1591 C CD2 . TYR   A 241 ? 1.0844 0.4868 0.8235 -0.0808 -0.0120 0.0881  614 TYR   A CD2 
1592 C CE1 . TYR   A 241 ? 1.0808 0.5091 0.8608 -0.0250 -0.0300 0.0663  614 TYR   A CE1 
1593 C CE2 . TYR   A 241 ? 1.2036 0.5614 0.9513 -0.0643 -0.0263 0.0879  614 TYR   A CE2 
1594 C CZ  . TYR   A 241 ? 1.1767 0.5495 0.9456 -0.0348 -0.0353 0.0757  614 TYR   A CZ  
1595 O OH  . TYR   A 241 ? 1.2380 0.5710 1.0182 -0.0157 -0.0495 0.0728  614 TYR   A OH  
1596 N N   . ASP   A 242 ? 0.8499 0.3698 0.6158 -0.1249 0.0304  0.0467  615 ASP   A N   
1597 C CA  . ASP   A 242 ? 0.8708 0.3695 0.6456 -0.1427 0.0334  0.0368  615 ASP   A CA  
1598 C C   . ASP   A 242 ? 0.7980 0.3435 0.5960 -0.1437 0.0413  0.0114  615 ASP   A C   
1599 O O   . ASP   A 242 ? 0.8096 0.3446 0.6189 -0.1557 0.0425  -0.0025 615 ASP   A O   
1600 C CB  . ASP   A 242 ? 0.9381 0.4122 0.6934 -0.1738 0.0396  0.0543  615 ASP   A CB  
1601 C CG  . ASP   A 242 ? 0.9064 0.4284 0.6558 -0.1945 0.0552  0.0561  615 ASP   A CG  
1602 O OD1 . ASP   A 242 ? 0.8750 0.4461 0.6320 -0.1823 0.0597  0.0467  615 ASP   A OD1 
1603 O OD2 . ASP   A 242 ? 1.0444 0.5543 0.7830 -0.2231 0.0626  0.0665  615 ASP   A OD2 
1604 N N   . GLU   A 243 ? 0.7439 0.3392 0.5475 -0.1323 0.0457  0.0063  616 GLU   A N   
1605 C CA  . GLU   A 243 ? 0.7440 0.3850 0.5674 -0.1287 0.0507  -0.0145 616 GLU   A CA  
1606 C C   . GLU   A 243 ? 0.7246 0.3872 0.5522 -0.1546 0.0607  -0.0215 616 GLU   A C   
1607 O O   . GLU   A 243 ? 0.7105 0.4058 0.5546 -0.1557 0.0632  -0.0398 616 GLU   A O   
1608 C CB  . GLU   A 243 ? 0.7700 0.4047 0.6094 -0.1127 0.0440  -0.0322 616 GLU   A CB  
1609 C CG  . GLU   A 243 ? 0.7944 0.4185 0.6336 -0.0870 0.0353  -0.0261 616 GLU   A CG  
1610 C CD  . GLU   A 243 ? 0.7562 0.3914 0.6121 -0.0670 0.0311  -0.0437 616 GLU   A CD  
1611 O OE1 . GLU   A 243 ? 0.7090 0.3497 0.5751 -0.0712 0.0328  -0.0632 616 GLU   A OE1 
1612 O OE2 . GLU   A 243 ? 0.7655 0.4088 0.6242 -0.0475 0.0265  -0.0383 616 GLU   A OE2 
1613 N N   . ASN   A 244 ? 0.7669 0.4187 0.5794 -0.1753 0.0668  -0.0062 617 ASN   A N   
1614 C CA  . ASN   A 244 ? 0.7446 0.4301 0.5633 -0.1999 0.0783  -0.0120 617 ASN   A CA  
1615 C C   . ASN   A 244 ? 0.7128 0.4540 0.5340 -0.1920 0.0854  -0.0139 617 ASN   A C   
1616 O O   . ASN   A 244 ? 0.7569 0.5407 0.5912 -0.2041 0.0935  -0.0247 617 ASN   A O   
1617 C CB  . ASN   A 244 ? 0.7731 0.4260 0.5760 -0.2286 0.0833  0.0042  617 ASN   A CB  
1618 C CG  . ASN   A 244 ? 0.8204 0.4184 0.6264 -0.2378 0.0756  0.0016  617 ASN   A CG  
1619 O OD1 . ASN   A 244 ? 0.8152 0.4221 0.6412 -0.2421 0.0744  -0.0198 617 ASN   A OD1 
1620 N ND2 . ASN   A 244 ? 0.8590 0.3998 0.6448 -0.2407 0.0692  0.0225  617 ASN   A ND2 
1621 N N   . THR   A 245 ? 0.6512 0.3930 0.4625 -0.1710 0.0812  -0.0051 618 THR   A N   
1622 C CA  . THR   A 245 ? 0.6398 0.4273 0.4532 -0.1625 0.0865  -0.0078 618 THR   A CA  
1623 C C   . THR   A 245 ? 0.6167 0.4091 0.4350 -0.1345 0.0776  -0.0101 618 THR   A C   
1624 O O   . THR   A 245 ? 0.6340 0.3954 0.4500 -0.1224 0.0686  -0.0060 618 THR   A O   
1625 C CB  . THR   A 245 ? 0.6698 0.4573 0.4612 -0.1731 0.0935  0.0067  618 THR   A CB  
1626 O OG1 . THR   A 245 ? 0.6766 0.4199 0.4464 -0.1664 0.0854  0.0239  618 THR   A OG1 
1627 C CG2 . THR   A 245 ? 0.6868 0.4788 0.4745 -0.2043 0.1050  0.0100  618 THR   A CG2 
1628 N N   . VAL   A 246 ? 0.5992 0.4310 0.4250 -0.1246 0.0802  -0.0162 619 VAL   A N   
1629 C CA  . VAL   A 246 ? 0.5837 0.4180 0.4101 -0.1020 0.0728  -0.0140 619 VAL   A CA  
1630 C C   . VAL   A 246 ? 0.5827 0.4307 0.3977 -0.1002 0.0765  -0.0097 619 VAL   A C   
1631 O O   . VAL   A 246 ? 0.5775 0.4514 0.3923 -0.1119 0.0861  -0.0142 619 VAL   A O   
1632 C CB  . VAL   A 246 ? 0.5798 0.4432 0.4262 -0.0881 0.0693  -0.0255 619 VAL   A CB  
1633 C CG1 . VAL   A 246 ? 0.6405 0.4933 0.4957 -0.0884 0.0656  -0.0323 619 VAL   A CG1 
1634 C CG2 . VAL   A 246 ? 0.5496 0.4561 0.4080 -0.0921 0.0756  -0.0361 619 VAL   A CG2 
1635 N N   . TYR   A 247 ? 0.5955 0.4296 0.4029 -0.0851 0.0687  -0.0033 620 TYR   A N   
1636 C CA  . TYR   A 247 ? 0.6202 0.4652 0.4166 -0.0802 0.0699  -0.0022 620 TYR   A CA  
1637 C C   . TYR   A 247 ? 0.5700 0.4332 0.3820 -0.0614 0.0641  -0.0100 620 TYR   A C   
1638 O O   . TYR   A 247 ? 0.5377 0.3913 0.3596 -0.0511 0.0562  -0.0081 620 TYR   A O   
1639 C CB  . TYR   A 247 ? 0.6363 0.4493 0.4101 -0.0790 0.0634  0.0110  620 TYR   A CB  
1640 C CG  . TYR   A 247 ? 0.7060 0.4898 0.4605 -0.0956 0.0654  0.0241  620 TYR   A CG  
1641 C CD1 . TYR   A 247 ? 0.7915 0.5828 0.5284 -0.1136 0.0758  0.0286  620 TYR   A CD1 
1642 C CD2 . TYR   A 247 ? 0.7773 0.5249 0.5302 -0.0920 0.0559  0.0332  620 TYR   A CD2 
1643 C CE1 . TYR   A 247 ? 0.8876 0.6473 0.6042 -0.1300 0.0765  0.0445  620 TYR   A CE1 
1644 C CE2 . TYR   A 247 ? 0.8174 0.5320 0.5526 -0.1050 0.0552  0.0468  620 TYR   A CE2 
1645 C CZ  . TYR   A 247 ? 0.8359 0.5541 0.5521 -0.1251 0.0653  0.0539  620 TYR   A CZ  
1646 O OH  . TYR   A 247 ? 1.1839 0.8645 0.8811 -0.1391 0.0635  0.0706  620 TYR   A OH  
1647 N N   . SER   A 248 ? 0.5633 0.4505 0.3757 -0.0568 0.0677  -0.0179 621 SER   A N   
1648 C CA  . SER   A 248 ? 0.5378 0.4344 0.3629 -0.0387 0.0605  -0.0238 621 SER   A CA  
1649 C C   . SER   A 248 ? 0.5469 0.4447 0.3599 -0.0328 0.0598  -0.0282 621 SER   A C   
1650 O O   . SER   A 248 ? 0.5530 0.4607 0.3508 -0.0420 0.0682  -0.0309 621 SER   A O   
1651 C CB  . SER   A 248 ? 0.4904 0.4190 0.3367 -0.0334 0.0629  -0.0342 621 SER   A CB  
1652 O OG  . SER   A 248 ? 0.4866 0.4451 0.3336 -0.0389 0.0728  -0.0445 621 SER   A OG  
1653 N N   . ILE   A 249 ? 0.5431 0.4326 0.3634 -0.0180 0.0497  -0.0299 622 ILE   A N   
1654 C CA  . ILE   A 249 ? 0.5603 0.4525 0.3746 -0.0092 0.0472  -0.0392 622 ILE   A CA  
1655 C C   . ILE   A 249 ? 0.5397 0.4377 0.3753 0.0072  0.0398  -0.0465 622 ILE   A C   
1656 O O   . ILE   A 249 ? 0.5308 0.4185 0.3790 0.0114  0.0327  -0.0382 622 ILE   A O   
1657 C CB  . ILE   A 249 ? 0.5834 0.4481 0.3798 -0.0106 0.0391  -0.0316 622 ILE   A CB  
1658 C CG1 . ILE   A 249 ? 0.6242 0.4919 0.4097 -0.0039 0.0367  -0.0438 622 ILE   A CG1 
1659 C CG2 . ILE   A 249 ? 0.6173 0.4610 0.4262 -0.0051 0.0277  -0.0220 622 ILE   A CG2 
1660 C CD1 . ILE   A 249 ? 0.6736 0.5199 0.4371 -0.0077 0.0290  -0.0372 622 ILE   A CD1 
1661 N N   . GLY   A 250 ? 0.5385 0.4539 0.3779 0.0169  0.0416  -0.0619 623 GLY   A N   
1662 C CA  . GLY   A 250 ? 0.5602 0.4786 0.4206 0.0341  0.0335  -0.0684 623 GLY   A CA  
1663 C C   . GLY   A 250 ? 0.5666 0.4843 0.4267 0.0477  0.0295  -0.0854 623 GLY   A C   
1664 O O   . GLY   A 250 ? 0.5568 0.4738 0.3982 0.0435  0.0332  -0.0931 623 GLY   A O   
1665 N N   . GLU   A 251 ? 0.5736 0.4936 0.4541 0.0649  0.0220  -0.0922 624 GLU   A N   
1666 C CA  . GLU   A 251 ? 0.5925 0.5010 0.4779 0.0816  0.0136  -0.1082 624 GLU   A CA  
1667 C C   . GLU   A 251 ? 0.5997 0.5411 0.4808 0.0873  0.0243  -0.1320 624 GLU   A C   
1668 O O   . GLU   A 251 ? 0.6160 0.5489 0.4944 0.0991  0.0195  -0.1498 624 GLU   A O   
1669 C CB  . GLU   A 251 ? 0.6144 0.5149 0.5238 0.0982  0.0020  -0.1048 624 GLU   A CB  
1670 C CG  . GLU   A 251 ? 0.6657 0.5457 0.5849 0.1181  -0.0099 -0.1203 624 GLU   A CG  
1671 C CD  . GLU   A 251 ? 0.6888 0.5572 0.6303 0.1343  -0.0228 -0.1125 624 GLU   A CD  
1672 O OE1 . GLU   A 251 ? 0.6476 0.5279 0.5951 0.1302  -0.0221 -0.0956 624 GLU   A OE1 
1673 O OE2 . GLU   A 251 ? 0.7606 0.6063 0.7120 0.1513  -0.0344 -0.1233 624 GLU   A OE2 
1674 N N   . ASP   A 252 ? 0.5532 0.5339 0.4346 0.0784  0.0390  -0.1338 625 ASP   A N   
1675 C CA  . ASP   A 252 ? 0.5568 0.5775 0.4350 0.0808  0.0521  -0.1552 625 ASP   A CA  
1676 C C   . ASP   A 252 ? 0.5830 0.6006 0.4290 0.0647  0.0606  -0.1553 625 ASP   A C   
1677 O O   . ASP   A 252 ? 0.6545 0.7064 0.4917 0.0626  0.0735  -0.1706 625 ASP   A O   
1678 C CB  . ASP   A 252 ? 0.5302 0.5980 0.4234 0.0752  0.0647  -0.1575 625 ASP   A CB  
1679 C CG  . ASP   A 252 ? 0.5291 0.5959 0.4160 0.0519  0.0707  -0.1364 625 ASP   A CG  
1680 O OD1 . ASP   A 252 ? 0.5180 0.5506 0.3844 0.0382  0.0682  -0.1198 625 ASP   A OD1 
1681 O OD2 . ASP   A 252 ? 0.5332 0.6326 0.4377 0.0490  0.0761  -0.1378 625 ASP   A OD2 
1682 N N   . GLY   A 253 ? 0.6385 0.6182 0.4666 0.0536  0.0533  -0.1378 626 GLY   A N   
1683 C CA  . GLY   A 253 ? 0.6373 0.6109 0.4330 0.0405  0.0575  -0.1360 626 GLY   A CA  
1684 C C   . GLY   A 253 ? 0.6321 0.6152 0.4100 0.0169  0.0699  -0.1181 626 GLY   A C   
1685 O O   . GLY   A 253 ? 0.6395 0.6149 0.3877 0.0047  0.0724  -0.1115 626 GLY   A O   
1686 N N   . LYS   A 254 ? 0.6018 0.5995 0.3969 0.0105  0.0760  -0.1102 627 LYS   A N   
1687 C CA  . LYS   A 254 ? 0.6563 0.6664 0.4387 -0.0121 0.0891  -0.0976 627 LYS   A CA  
1688 C C   . LYS   A 254 ? 0.6161 0.5899 0.3940 -0.0228 0.0820  -0.0748 627 LYS   A C   
1689 O O   . LYS   A 254 ? 0.5924 0.5479 0.3879 -0.0140 0.0714  -0.0696 627 LYS   A O   
1690 C CB  . LYS   A 254 ? 0.7163 0.7691 0.5216 -0.0149 0.1006  -0.1063 627 LYS   A CB  
1691 C CG  . LYS   A 254 ? 0.7888 0.8857 0.5998 -0.0049 0.1101  -0.1304 627 LYS   A CG  
1692 C CD  . LYS   A 254 ? 0.8806 1.0271 0.7180 -0.0072 0.1212  -0.1404 627 LYS   A CD  
1693 C CE  . LYS   A 254 ? 0.9778 1.1733 0.8217 0.0032  0.1321  -0.1659 627 LYS   A CE  
1694 N NZ  . LYS   A 254 ? 1.0479 1.2974 0.9062 -0.0124 0.1490  -0.1707 627 LYS   A NZ  
1695 N N   . PHE   A 255 ? 0.6192 0.5832 0.3717 -0.0414 0.0879  -0.0613 628 PHE   A N   
1696 C CA  . PHE   A 255 ? 0.6051 0.5419 0.3533 -0.0545 0.0854  -0.0416 628 PHE   A CA  
1697 C C   . PHE   A 255 ? 0.5992 0.5575 0.3517 -0.0734 0.0995  -0.0392 628 PHE   A C   
1698 O O   . PHE   A 255 ? 0.6316 0.6106 0.3677 -0.0876 0.1122  -0.0398 628 PHE   A O   
1699 C CB  . PHE   A 255 ? 0.6453 0.5536 0.3611 -0.0627 0.0811  -0.0270 628 PHE   A CB  
1700 C CG  . PHE   A 255 ? 0.6657 0.5431 0.3751 -0.0754 0.0782  -0.0069 628 PHE   A CG  
1701 C CD1 . PHE   A 255 ? 0.6727 0.5246 0.3980 -0.0665 0.0663  -0.0009 628 PHE   A CD1 
1702 C CD2 . PHE   A 255 ? 0.7371 0.6097 0.4240 -0.0957 0.0870  0.0059  628 PHE   A CD2 
1703 C CE1 . PHE   A 255 ? 0.6690 0.4933 0.3908 -0.0752 0.0634  0.0137  628 PHE   A CE1 
1704 C CE2 . PHE   A 255 ? 0.7444 0.5825 0.4264 -0.1052 0.0824  0.0234  628 PHE   A CE2 
1705 C CZ  . PHE   A 255 ? 0.7285 0.5433 0.4293 -0.0936 0.0705  0.0255  628 PHE   A CZ  
1706 N N   . ILE   A 256 ? 0.5569 0.5101 0.3299 -0.0754 0.0972  -0.0358 629 ILE   A N   
1707 C CA  . ILE   A 256 ? 0.5544 0.5315 0.3382 -0.0926 0.1088  -0.0377 629 ILE   A CA  
1708 C C   . ILE   A 256 ? 0.5926 0.5366 0.3762 -0.1041 0.1045  -0.0242 629 ILE   A C   
1709 O O   . ILE   A 256 ? 0.5724 0.4907 0.3626 -0.0923 0.0927  -0.0201 629 ILE   A O   
1710 C CB  . ILE   A 256 ? 0.5373 0.5543 0.3520 -0.0811 0.1102  -0.0550 629 ILE   A CB  
1711 C CG1 . ILE   A 256 ? 0.5640 0.6067 0.3818 -0.0630 0.1108  -0.0706 629 ILE   A CG1 
1712 C CG2 . ILE   A 256 ? 0.5279 0.5774 0.3554 -0.1009 0.1224  -0.0593 629 ILE   A CG2 
1713 C CD1 . ILE   A 256 ? 0.5409 0.6305 0.3885 -0.0524 0.1142  -0.0888 629 ILE   A CD1 
1714 N N   . GLN   A 257 ? 0.6150 0.5612 0.3919 -0.1279 0.1146  -0.0183 630 GLN   A N   
1715 C CA  . GLN   A 257 ? 0.6330 0.5491 0.4125 -0.1402 0.1114  -0.0094 630 GLN   A CA  
1716 C C   . GLN   A 257 ? 0.5995 0.5479 0.4040 -0.1515 0.1184  -0.0215 630 GLN   A C   
1717 O O   . GLN   A 257 ? 0.5984 0.5843 0.4070 -0.1657 0.1310  -0.0278 630 GLN   A O   
1718 C CB  . GLN   A 257 ? 0.6962 0.5801 0.4465 -0.1600 0.1149  0.0091  630 GLN   A CB  
1719 C CG  . GLN   A 257 ? 0.7596 0.5993 0.5098 -0.1695 0.1084  0.0195  630 GLN   A CG  
1720 C CD  . GLN   A 257 ? 0.8540 0.6605 0.5761 -0.1911 0.1116  0.0398  630 GLN   A CD  
1721 O OE1 . GLN   A 257 ? 0.9270 0.7494 0.6278 -0.2023 0.1209  0.0469  630 GLN   A OE1 
1722 N NE2 . GLN   A 257 ? 0.8163 0.5764 0.5371 -0.1968 0.1038  0.0493  630 GLN   A NE2 
1723 N N   . TRP   A 258 ? 0.5914 0.5281 0.4123 -0.1461 0.1103  -0.0255 631 TRP   A N   
1724 C CA  . TRP   A 258 ? 0.5858 0.5562 0.4319 -0.1528 0.1134  -0.0397 631 TRP   A CA  
1725 C C   . TRP   A 258 ? 0.6331 0.5748 0.4805 -0.1709 0.1119  -0.0372 631 TRP   A C   
1726 O O   . TRP   A 258 ? 0.6204 0.5211 0.4606 -0.1630 0.1027  -0.0306 631 TRP   A O   
1727 C CB  . TRP   A 258 ? 0.5438 0.5321 0.4085 -0.1281 0.1037  -0.0498 631 TRP   A CB  
1728 C CG  . TRP   A 258 ? 0.5155 0.5200 0.3800 -0.1072 0.1014  -0.0521 631 TRP   A CG  
1729 C CD1 . TRP   A 258 ? 0.4817 0.4600 0.3352 -0.0898 0.0930  -0.0448 631 TRP   A CD1 
1730 C CD2 . TRP   A 258 ? 0.4879 0.5404 0.3674 -0.1012 0.1067  -0.0651 631 TRP   A CD2 
1731 N NE1 . TRP   A 258 ? 0.4804 0.4828 0.3395 -0.0744 0.0926  -0.0525 631 TRP   A NE1 
1732 C CE2 . TRP   A 258 ? 0.4796 0.5276 0.3552 -0.0791 0.1007  -0.0654 631 TRP   A CE2 
1733 C CE3 . TRP   A 258 ? 0.4985 0.5986 0.3970 -0.1116 0.1151  -0.0777 631 TRP   A CE3 
1734 C CZ2 . TRP   A 258 ? 0.4846 0.5705 0.3737 -0.0655 0.1026  -0.0786 631 TRP   A CZ2 
1735 C CZ3 . TRP   A 258 ? 0.4913 0.6348 0.4045 -0.0977 0.1176  -0.0905 631 TRP   A CZ3 
1736 C CH2 . TRP   A 258 ? 0.4942 0.6287 0.4024 -0.0738 0.1113  -0.0912 631 TRP   A CH2 
1737 N N   . ASN   A 259 ? 0.6889 0.6573 0.5504 -0.1926 0.1199  -0.0459 632 ASN   A N   
1738 C CA  . ASN   A 259 ? 0.7115 0.6536 0.5767 -0.2127 0.1185  -0.0469 632 ASN   A CA  
1739 C C   . ASN   A 259 ? 0.6970 0.6474 0.5812 -0.1988 0.1084  -0.0622 632 ASN   A C   
1740 O O   . ASN   A 259 ? 0.7033 0.7018 0.6083 -0.1970 0.1091  -0.0772 632 ASN   A O   
1741 C CB  . ASN   A 259 ? 0.6984 0.6673 0.5718 -0.2447 0.1311  -0.0503 632 ASN   A CB  
1742 C CG  . ASN   A 259 ? 0.7418 0.6766 0.6184 -0.2693 0.1292  -0.0510 632 ASN   A CG  
1743 O OD1 . ASN   A 259 ? 0.7463 0.6492 0.6256 -0.2592 0.1181  -0.0562 632 ASN   A OD1 
1744 N ND2 . ASN   A 259 ? 0.7684 0.7104 0.6456 -0.3024 0.1403  -0.0469 632 ASN   A ND2 
1745 N N   . ILE   A 260 ? 0.6793 0.5842 0.5558 -0.1903 0.0991  -0.0586 633 ILE   A N   
1746 C CA  . ILE   A 260 ? 0.7271 0.6374 0.6159 -0.1749 0.0898  -0.0718 633 ILE   A CA  
1747 C C   . ILE   A 260 ? 0.7665 0.6952 0.6725 -0.1934 0.0903  -0.0897 633 ILE   A C   
1748 O O   . ILE   A 260 ? 0.8182 0.7616 0.7341 -0.1826 0.0834  -0.1034 633 ILE   A O   
1749 C CB  . ILE   A 260 ? 0.7613 0.6207 0.6381 -0.1619 0.0815  -0.0647 633 ILE   A CB  
1750 C CG1 . ILE   A 260 ? 0.7664 0.6408 0.6501 -0.1381 0.0741  -0.0718 633 ILE   A CG1 
1751 C CG2 . ILE   A 260 ? 0.8690 0.6863 0.7444 -0.1794 0.0796  -0.0683 633 ILE   A CG2 
1752 C CD1 . ILE   A 260 ? 0.8711 0.7790 0.7566 -0.1213 0.0741  -0.0671 633 ILE   A CD1 
1753 N N   . HIS   A 261 ? 0.7606 0.6861 0.6685 -0.2228 0.0982  -0.0891 634 HIS   A N   
1754 C CA  . HIS   A 261 ? 0.8503 0.7918 0.7760 -0.2449 0.0984  -0.1067 634 HIS   A CA  
1755 C C   . HIS   A 261 ? 0.7926 0.8032 0.7389 -0.2541 0.1050  -0.1175 634 HIS   A C   
1756 O O   . HIS   A 261 ? 0.8093 0.8404 0.7726 -0.2758 0.1058  -0.1322 634 HIS   A O   
1757 C CB  . HIS   A 261 ? 0.8371 0.7305 0.7562 -0.2763 0.1019  -0.1007 634 HIS   A CB  
1758 C CG  . HIS   A 261 ? 0.9009 0.7205 0.8013 -0.2695 0.0944  -0.0895 634 HIS   A CG  
1759 N ND1 . HIS   A 261 ? 0.9303 0.7231 0.8334 -0.2539 0.0835  -0.1025 634 HIS   A ND1 
1760 C CD2 . HIS   A 261 ? 1.0109 0.7806 0.8893 -0.2737 0.0956  -0.0664 634 HIS   A CD2 
1761 C CE1 . HIS   A 261 ? 1.0250 0.7552 0.9119 -0.2477 0.0782  -0.0890 634 HIS   A CE1 
1762 N NE2 . HIS   A 261 ? 1.0627 0.7772 0.9338 -0.2590 0.0845  -0.0658 634 HIS   A NE2 
1763 N N   . LYS   A 262 ? 0.7252 0.7722 0.6723 -0.2362 0.1083  -0.1125 635 LYS   A N   
1764 C CA  . LYS   A 262 ? 0.7258 0.8390 0.6935 -0.2417 0.1150  -0.1223 635 LYS   A CA  
1765 C C   . LYS   A 262 ? 0.7897 0.9309 0.7574 -0.2109 0.1131  -0.1193 635 LYS   A C   
1766 O O   . LYS   A 262 ? 0.8963 1.0300 0.8508 -0.2071 0.1201  -0.1075 635 LYS   A O   
1767 C CB  . LYS   A 262 ? 0.7377 0.8551 0.7030 -0.2725 0.1299  -0.1146 635 LYS   A CB  
1768 C CG  . LYS   A 262 ? 0.8342 0.9447 0.8102 -0.3088 0.1330  -0.1216 635 LYS   A CG  
1769 C CD  . LYS   A 262 ? 0.8609 0.9370 0.8209 -0.3409 0.1449  -0.1040 635 LYS   A CD  
1770 C CE  . LYS   A 262 ? 0.8912 0.9598 0.8652 -0.3778 0.1465  -0.1121 635 LYS   A CE  
1771 N NZ  . LYS   A 262 ? 0.9050 0.9095 0.8712 -0.3766 0.1338  -0.1148 635 LYS   A NZ  
1772 N N   . SER   A 263 ? 0.8129 0.9859 0.7946 -0.1896 0.1028  -0.1302 636 SER   A N   
1773 C CA  . SER   A 263 ? 0.7279 0.9127 0.7079 -0.1572 0.0964  -0.1258 636 SER   A CA  
1774 C C   . SER   A 263 ? 0.7288 0.9461 0.7146 -0.1513 0.1047  -0.1250 636 SER   A C   
1775 O O   . SER   A 263 ? 0.6550 0.9268 0.6630 -0.1572 0.1092  -0.1375 636 SER   A O   
1776 C CB  . SER   A 263 ? 0.7525 0.9723 0.7481 -0.1415 0.0841  -0.1374 636 SER   A CB  
1777 O OG  . SER   A 263 ? 0.7638 1.0114 0.7666 -0.1143 0.0782  -0.1359 636 SER   A OG  
1778 N N   . GLY   A 264 ? 0.7906 0.9775 0.7576 -0.1380 0.1061  -0.1123 637 GLY   A N   
1779 C CA  . GLY   A 264 ? 0.6846 0.8984 0.6544 -0.1272 0.1124  -0.1140 637 GLY   A CA  
1780 C C   . GLY   A 264 ? 0.7928 1.0174 0.7567 -0.1531 0.1291  -0.1128 637 GLY   A C   
1781 O O   . GLY   A 264 ? 0.7067 0.9640 0.6745 -0.1475 0.1372  -0.1181 637 GLY   A O   
1782 N N   . LEU   A 265 ? 0.8222 1.0194 0.7763 -0.1817 0.1344  -0.1059 638 LEU   A N   
1783 C CA  . LEU   A 265 ? 0.7307 0.9277 0.6723 -0.2087 0.1499  -0.0985 638 LEU   A CA  
1784 C C   . LEU   A 265 ? 0.6956 0.8414 0.6038 -0.2019 0.1495  -0.0805 638 LEU   A C   
1785 O O   . LEU   A 265 ? 0.6734 0.7634 0.5650 -0.2016 0.1413  -0.0684 638 LEU   A O   
1786 C CB  . LEU   A 265 ? 0.7383 0.9244 0.6831 -0.2444 0.1552  -0.0967 638 LEU   A CB  
1787 C CG  . LEU   A 265 ? 0.7955 0.9718 0.7218 -0.2754 0.1710  -0.0830 638 LEU   A CG  
1788 C CD1 . LEU   A 265 ? 0.8008 1.0405 0.7352 -0.2775 0.1861  -0.0902 638 LEU   A CD1 
1789 C CD2 . LEU   A 265 ? 0.7981 0.9606 0.7304 -0.3119 0.1749  -0.0811 638 LEU   A CD2 
1790 N N   . LYS   A 266 ? 0.6830 0.8516 0.5832 -0.1941 0.1575  -0.0812 639 LYS   A N   
1791 C CA  . LYS   A 266 ? 0.7084 0.8375 0.5764 -0.1890 0.1574  -0.0663 639 LYS   A CA  
1792 C C   . LYS   A 266 ? 0.7052 0.8044 0.5500 -0.2211 0.1663  -0.0489 639 LYS   A C   
1793 O O   . LYS   A 266 ? 0.6934 0.8182 0.5472 -0.2484 0.1779  -0.0507 639 LYS   A O   
1794 C CB  . LYS   A 266 ? 0.7440 0.9072 0.6064 -0.1757 0.1649  -0.0738 639 LYS   A CB  
1795 C CG  . LYS   A 266 ? 0.7555 0.9472 0.6394 -0.1431 0.1568  -0.0909 639 LYS   A CG  
1796 C CD  . LYS   A 266 ? 0.7750 0.9845 0.6472 -0.1289 0.1622  -0.0981 639 LYS   A CD  
1797 C CE  . LYS   A 266 ? 0.8440 1.1165 0.7448 -0.1137 0.1672  -0.1212 639 LYS   A CE  
1798 N NZ  . LYS   A 266 ? 0.8430 1.1089 0.7603 -0.0800 0.1509  -0.1301 639 LYS   A NZ  
1799 N N   . VAL   A 267 ? 0.7173 0.7618 0.5329 -0.2176 0.1596  -0.0313 640 VAL   A N   
1800 C CA  . VAL   A 267 ? 0.7320 0.7421 0.5200 -0.2440 0.1657  -0.0108 640 VAL   A CA  
1801 C C   . VAL   A 267 ? 0.7439 0.7632 0.5032 -0.2418 0.1729  -0.0033 640 VAL   A C   
1802 O O   . VAL   A 267 ? 0.7472 0.7767 0.4881 -0.2673 0.1865  0.0074  640 VAL   A O   
1803 C CB  . VAL   A 267 ? 0.7383 0.6799 0.5142 -0.2410 0.1511  0.0036  640 VAL   A CB  
1804 C CG1 . VAL   A 267 ? 0.8343 0.7327 0.5796 -0.2665 0.1546  0.0279  640 VAL   A CG1 
1805 C CG2 . VAL   A 267 ? 0.7141 0.6511 0.5176 -0.2415 0.1442  -0.0081 640 VAL   A CG2 
1806 N N   . SER   A 268 ? 0.7120 0.7281 0.4672 -0.2120 0.1635  -0.0091 641 SER   A N   
1807 C CA  . SER   A 268 ? 0.6975 0.7276 0.4278 -0.2058 0.1687  -0.0081 641 SER   A CA  
1808 C C   . SER   A 268 ? 0.6761 0.7165 0.4185 -0.1719 0.1585  -0.0245 641 SER   A C   
1809 O O   . SER   A 268 ? 0.6207 0.6455 0.3838 -0.1547 0.1457  -0.0294 641 SER   A O   
1810 C CB  . SER   A 268 ? 0.7443 0.7249 0.4355 -0.2148 0.1640  0.0163  641 SER   A CB  
1811 O OG  . SER   A 268 ? 0.7613 0.6932 0.4520 -0.1953 0.1449  0.0225  641 SER   A OG  
1812 N N   . GLU   A 269 ? 0.7007 0.7627 0.4266 -0.1634 0.1633  -0.0315 642 GLU   A N   
1813 C CA  . GLU   A 269 ? 0.7251 0.8035 0.4646 -0.1338 0.1560  -0.0508 642 GLU   A CA  
1814 C C   . GLU   A 269 ? 0.7369 0.8164 0.4447 -0.1290 0.1579  -0.0519 642 GLU   A C   
1815 O O   . GLU   A 269 ? 0.7050 0.8129 0.3939 -0.1455 0.1731  -0.0513 642 GLU   A O   
1816 C CB  . GLU   A 269 ? 0.7893 0.9250 0.5632 -0.1296 0.1654  -0.0722 642 GLU   A CB  
1817 C CG  . GLU   A 269 ? 0.8786 1.0432 0.6656 -0.1013 0.1626  -0.0954 642 GLU   A CG  
1818 C CD  . GLU   A 269 ? 0.9104 1.1268 0.7363 -0.0920 0.1669  -0.1154 642 GLU   A CD  
1819 O OE1 . GLU   A 269 ? 0.9778 1.2393 0.8126 -0.1114 0.1830  -0.1199 642 GLU   A OE1 
1820 O OE2 . GLU   A 269 ? 0.9934 1.2048 0.8412 -0.0661 0.1535  -0.1252 642 GLU   A OE2 
1821 N N   . TYR   A 270 ? 0.7728 0.8211 0.4733 -0.1086 0.1422  -0.0528 643 TYR   A N   
1822 C CA  . TYR   A 270 ? 0.7899 0.8388 0.4612 -0.1018 0.1410  -0.0573 643 TYR   A CA  
1823 C C   . TYR   A 270 ? 0.7343 0.7845 0.4240 -0.0727 0.1292  -0.0786 643 TYR   A C   
1824 O O   . TYR   A 270 ? 0.7007 0.7248 0.4121 -0.0593 0.1153  -0.0769 643 TYR   A O   
1825 C CB  . TYR   A 270 ? 0.8471 0.8480 0.4857 -0.1112 0.1310  -0.0325 643 TYR   A CB  
1826 C CG  . TYR   A 270 ? 0.9800 0.9715 0.6003 -0.1400 0.1408  -0.0093 643 TYR   A CG  
1827 C CD1 . TYR   A 270 ? 1.0197 1.0342 0.6077 -0.1596 0.1556  -0.0027 643 TYR   A CD1 
1828 C CD2 . TYR   A 270 ? 1.0030 0.9630 0.6380 -0.1488 0.1359  0.0053  643 TYR   A CD2 
1829 C CE1 . TYR   A 270 ? 1.0581 1.0603 0.6288 -0.1884 0.1644  0.0208  643 TYR   A CE1 
1830 C CE2 . TYR   A 270 ? 1.0134 0.9593 0.6330 -0.1759 0.1438  0.0256  643 TYR   A CE2 
1831 C CZ  . TYR   A 270 ? 1.1186 1.0836 0.7059 -0.1965 0.1578  0.0350  643 TYR   A CZ  
1832 O OH  . TYR   A 270 ? 1.2665 1.2151 0.8370 -0.2259 0.1658  0.0576  643 TYR   A OH  
1833 N N   . SER   A 271 ? 0.7575 0.8390 0.4387 -0.0635 0.1353  -0.0990 644 SER   A N   
1834 C CA  . SER   A 271 ? 0.7474 0.8205 0.4365 -0.0377 0.1224  -0.1186 644 SER   A CA  
1835 C C   . SER   A 271 ? 0.7394 0.7726 0.3985 -0.0375 0.1085  -0.1079 644 SER   A C   
1836 O O   . SER   A 271 ? 0.7862 0.8283 0.4103 -0.0465 0.1138  -0.1070 644 SER   A O   
1837 C CB  . SER   A 271 ? 0.7620 0.8835 0.4529 -0.0271 0.1340  -0.1474 644 SER   A CB  
1838 O OG  . SER   A 271 ? 0.7670 0.9267 0.4926 -0.0232 0.1434  -0.1587 644 SER   A OG  
1839 N N   . LEU   A 272 ? 0.7142 0.7071 0.3869 -0.0279 0.0907  -0.0999 645 LEU   A N   
1840 C CA  . LEU   A 272 ? 0.7604 0.7203 0.4113 -0.0255 0.0756  -0.0932 645 LEU   A CA  
1841 C C   . LEU   A 272 ? 0.7600 0.7274 0.4085 -0.0083 0.0691  -0.1198 645 LEU   A C   
1842 O O   . LEU   A 272 ? 0.7326 0.7210 0.4037 0.0059  0.0729  -0.1419 645 LEU   A O   
1843 C CB  . LEU   A 272 ? 0.7865 0.7076 0.4567 -0.0220 0.0603  -0.0772 645 LEU   A CB  
1844 C CG  . LEU   A 272 ? 0.8258 0.7314 0.4932 -0.0379 0.0634  -0.0518 645 LEU   A CG  
1845 C CD1 . LEU   A 272 ? 0.8464 0.7175 0.5288 -0.0320 0.0476  -0.0397 645 LEU   A CD1 
1846 C CD2 . LEU   A 272 ? 0.8736 0.7767 0.5029 -0.0547 0.0685  -0.0369 645 LEU   A CD2 
1847 N N   . PRO   A 273 ? 0.7849 0.7361 0.4061 -0.0084 0.0582  -0.1202 646 PRO   A N   
1848 C CA  . PRO   A 273 ? 0.8097 0.7590 0.4325 0.0082  0.0477  -0.1468 646 PRO   A CA  
1849 C C   . PRO   A 273 ? 0.7640 0.6874 0.4266 0.0231  0.0343  -0.1518 646 PRO   A C   
1850 O O   . PRO   A 273 ? 0.7527 0.6530 0.4320 0.0192  0.0280  -0.1312 646 PRO   A O   
1851 C CB  . PRO   A 273 ? 0.8316 0.7639 0.4193 0.0020  0.0353  -0.1403 646 PRO   A CB  
1852 C CG  . PRO   A 273 ? 0.8503 0.7876 0.4092 -0.0181 0.0451  -0.1124 646 PRO   A CG  
1853 C CD  . PRO   A 273 ? 0.7981 0.7324 0.3857 -0.0236 0.0540  -0.0965 646 PRO   A CD  
1854 N N   . SER   A 274 ? 0.7770 0.7059 0.4538 0.0405  0.0308  -0.1796 647 SER   A N   
1855 C CA  . SER   A 274 ? 0.7684 0.6718 0.4806 0.0556  0.0176  -0.1861 647 SER   A CA  
1856 C C   . SER   A 274 ? 0.7178 0.5809 0.4370 0.0501  0.0003  -0.1669 647 SER   A C   
1857 O O   . SER   A 274 ? 0.6920 0.5369 0.4397 0.0547  -0.0058 -0.1577 647 SER   A O   
1858 C CB  . SER   A 274 ? 0.8131 0.7183 0.5296 0.0737  0.0119  -0.2197 647 SER   A CB  
1859 O OG  . SER   A 274 ? 0.9109 0.8452 0.6475 0.0870  0.0233  -0.2354 647 SER   A OG  
1860 N N   . ASP   A 275 ? 0.7201 0.5729 0.4135 0.0415  -0.0079 -0.1634 648 ASP   A N   
1861 C CA  . ASP   A 275 ? 0.7283 0.5489 0.4291 0.0377  -0.0261 -0.1521 648 ASP   A CA  
1862 C C   . ASP   A 275 ? 0.7401 0.5536 0.4450 0.0261  -0.0245 -0.1210 648 ASP   A C   
1863 O O   . ASP   A 275 ? 0.7497 0.5427 0.4629 0.0220  -0.0377 -0.1087 648 ASP   A O   
1864 C CB  . ASP   A 275 ? 0.7727 0.5902 0.4463 0.0351  -0.0374 -0.1645 648 ASP   A CB  
1865 C CG  . ASP   A 275 ? 0.8103 0.6457 0.4441 0.0234  -0.0313 -0.1530 648 ASP   A CG  
1866 O OD1 . ASP   A 275 ? 0.8198 0.6697 0.4457 0.0160  -0.0165 -0.1363 648 ASP   A OD1 
1867 O OD2 . ASP   A 275 ? 0.8996 0.7328 0.5105 0.0209  -0.0427 -0.1595 648 ASP   A OD2 
1868 N N   . ALA   A 276 ? 0.7124 0.5444 0.4130 0.0207  -0.0085 -0.1102 649 ALA   A N   
1869 C CA  . ALA   A 276 ? 0.6992 0.5234 0.4099 0.0126  -0.0060 -0.0852 649 ALA   A CA  
1870 C C   . ALA   A 276 ? 0.6764 0.4931 0.4225 0.0197  -0.0075 -0.0826 649 ALA   A C   
1871 O O   . ALA   A 276 ? 0.6132 0.4188 0.3716 0.0152  -0.0104 -0.0649 649 ALA   A O   
1872 C CB  . ALA   A 276 ? 0.6945 0.5386 0.3877 0.0023  0.0105  -0.0762 649 ALA   A CB  
1873 N N   . THR   A 277 ? 0.6739 0.4996 0.4352 0.0314  -0.0047 -0.0999 650 THR   A N   
1874 C CA  . THR   A 277 ? 0.6403 0.4618 0.4316 0.0385  -0.0059 -0.0951 650 THR   A CA  
1875 C C   . THR   A 277 ? 0.6772 0.4786 0.4863 0.0513  -0.0190 -0.1078 650 THR   A C   
1876 O O   . THR   A 277 ? 0.6434 0.4355 0.4758 0.0573  -0.0232 -0.1011 650 THR   A O   
1877 C CB  . THR   A 277 ? 0.6463 0.4975 0.4437 0.0411  0.0088  -0.0996 650 THR   A CB  
1878 O OG1 . THR   A 277 ? 0.6615 0.5303 0.4481 0.0484  0.0134  -0.1226 650 THR   A OG1 
1879 C CG2 . THR   A 277 ? 0.6354 0.4997 0.4222 0.0262  0.0204  -0.0837 650 THR   A CG2 
1880 N N   . GLY   A 278 ? 0.7423 0.5348 0.5396 0.0545  -0.0267 -0.1251 651 GLY   A N   
1881 C CA  . GLY   A 278 ? 0.7814 0.5482 0.5957 0.0650  -0.0410 -0.1380 651 GLY   A CA  
1882 C C   . GLY   A 278 ? 0.8252 0.5999 0.6562 0.0828  -0.0377 -0.1541 651 GLY   A C   
1883 O O   . GLY   A 278 ? 0.8478 0.6551 0.6720 0.0876  -0.0239 -0.1643 651 GLY   A O   
1884 N N   . PRO   A 279 ? 0.8722 0.6183 0.7261 0.0934  -0.0507 -0.1570 652 PRO   A N   
1885 C CA  . PRO   A 279 ? 0.8259 0.5351 0.6909 0.0849  -0.0661 -0.1430 652 PRO   A CA  
1886 C C   . PRO   A 279 ? 0.7880 0.4837 0.6382 0.0750  -0.0755 -0.1520 652 PRO   A C   
1887 O O   . PRO   A 279 ? 0.8164 0.5196 0.6502 0.0805  -0.0754 -0.1768 652 PRO   A O   
1888 C CB  . PRO   A 279 ? 0.9251 0.6063 0.8137 0.1010  -0.0777 -0.1514 652 PRO   A CB  
1889 C CG  . PRO   A 279 ? 0.9511 0.6608 0.8457 0.1179  -0.0669 -0.1603 652 PRO   A CG  
1890 C CD  . PRO   A 279 ? 0.9547 0.7029 0.8256 0.1147  -0.0519 -0.1755 652 PRO   A CD  
1891 N N   . PHE   A 280 ? 0.7400 0.4190 0.5967 0.0606  -0.0841 -0.1332 653 PHE   A N   
1892 C CA  . PHE   A 280 ? 0.7607 0.4332 0.6046 0.0500  -0.0938 -0.1398 653 PHE   A CA  
1893 C C   . PHE   A 280 ? 0.8050 0.4420 0.6638 0.0514  -0.1118 -0.1552 653 PHE   A C   
1894 O O   . PHE   A 280 ? 0.8032 0.4145 0.6860 0.0488  -0.1196 -0.1427 653 PHE   A O   
1895 C CB  . PHE   A 280 ? 0.7676 0.4480 0.6126 0.0346  -0.0928 -0.1132 653 PHE   A CB  
1896 C CG  . PHE   A 280 ? 0.7337 0.4424 0.5657 0.0333  -0.0764 -0.0990 653 PHE   A CG  
1897 C CD1 . PHE   A 280 ? 0.7078 0.4374 0.5113 0.0333  -0.0682 -0.1073 653 PHE   A CD1 
1898 C CD2 . PHE   A 280 ? 0.6997 0.4132 0.5465 0.0304  -0.0697 -0.0771 653 PHE   A CD2 
1899 C CE1 . PHE   A 280 ? 0.7331 0.4832 0.5256 0.0297  -0.0541 -0.0934 653 PHE   A CE1 
1900 C CE2 . PHE   A 280 ? 0.7128 0.4484 0.5486 0.0280  -0.0561 -0.0663 653 PHE   A CE2 
1901 C CZ  . PHE   A 280 ? 0.6847 0.4364 0.4945 0.0273  -0.0485 -0.0742 653 PHE   A CZ  
1902 N N   . VAL   A 281 ? 0.8106 0.4455 0.6533 0.0543  -0.1187 -0.1824 654 VAL   A N   
1903 C CA  . VAL   A 281 ? 0.8427 0.4431 0.6978 0.0586  -0.1352 -0.2047 654 VAL   A CA  
1904 C C   . VAL   A 281 ? 0.8750 0.4720 0.7183 0.0456  -0.1487 -0.2164 654 VAL   A C   
1905 O O   . VAL   A 281 ? 0.9028 0.5262 0.7174 0.0455  -0.1447 -0.2283 654 VAL   A O   
1906 C CB  . VAL   A 281 ? 0.8495 0.4494 0.7002 0.0804  -0.1324 -0.2364 654 VAL   A CB  
1907 C CG1 . VAL   A 281 ? 0.9106 0.4691 0.7742 0.0851  -0.1515 -0.2620 654 VAL   A CG1 
1908 C CG2 . VAL   A 281 ? 0.8227 0.4296 0.6878 0.0952  -0.1211 -0.2270 654 VAL   A CG2 
1909 N N   . LEU   A 282 ? 0.9046 0.4699 0.7703 0.0339  -0.1652 -0.2126 655 LEU   A N   
1910 C CA  . LEU   A 282 ? 0.9494 0.5073 0.8103 0.0220  -0.1820 -0.2290 655 LEU   A CA  
1911 C C   . LEU   A 282 ? 0.9955 0.5105 0.8711 0.0268  -0.1983 -0.2572 655 LEU   A C   
1912 O O   . LEU   A 282 ? 0.9777 0.4571 0.8815 0.0240  -0.2049 -0.2461 655 LEU   A O   
1913 C CB  . LEU   A 282 ? 0.9347 0.4960 0.8132 0.0012  -0.1872 -0.1998 655 LEU   A CB  
1914 C CG  . LEU   A 282 ? 0.9755 0.5462 0.8483 -0.0134 -0.2025 -0.2090 655 LEU   A CG  
1915 C CD1 . LEU   A 282 ? 0.9934 0.5968 0.8274 -0.0066 -0.1990 -0.2238 655 LEU   A CD1 
1916 C CD2 . LEU   A 282 ? 0.9325 0.5154 0.8265 -0.0306 -0.2037 -0.1783 655 LEU   A CD2 
1917 N N   . SER   A 283 ? 1.0556 0.5736 0.9104 0.0347  -0.2047 -0.2940 656 SER   A N   
1918 C CA  . SER   A 283 ? 1.1338 0.6108 1.0002 0.0416  -0.2209 -0.3272 656 SER   A CA  
1919 C C   . SER   A 283 ? 1.1742 0.6438 1.0365 0.0253  -0.2406 -0.3469 656 SER   A C   
1920 O O   . SER   A 283 ? 1.1368 0.6420 0.9770 0.0161  -0.2403 -0.3445 656 SER   A O   
1921 C CB  . SER   A 283 ? 1.1612 0.6470 1.0100 0.0673  -0.2130 -0.3614 656 SER   A CB  
1922 O OG  . SER   A 283 ? 1.1948 0.7006 1.0445 0.0818  -0.1935 -0.3446 656 SER   A OG  
1923 N N   . GLY   A 284 ? 1.3287 0.7498 1.2136 0.0219  -0.2593 -0.3663 657 GLY   A N   
1924 C CA  . GLY   A 284 ? 1.3782 0.7875 1.2557 0.0150  -0.2790 -0.4033 657 GLY   A CA  
1925 C C   . GLY   A 284 ? 1.4648 0.8413 1.3417 0.0373  -0.2850 -0.4460 657 GLY   A C   
1926 O O   . GLY   A 284 ? 1.4635 0.8342 1.3442 0.0590  -0.2727 -0.4450 657 GLY   A O   
1927 N N   . TYR   A 285 ? 1.5520 0.9065 1.4269 0.0325  -0.3052 -0.4845 658 TYR   A N   
1928 C CA  . TYR   A 285 ? 1.5568 0.8865 1.4265 0.0560  -0.3110 -0.5326 658 TYR   A CA  
1929 C C   . TYR   A 285 ? 1.5731 0.8362 1.4809 0.0644  -0.3197 -0.5295 658 TYR   A C   
1930 O O   . TYR   A 285 ? 1.8484 1.0843 1.7587 0.0884  -0.3246 -0.5667 658 TYR   A O   
1931 C CB  . TYR   A 285 ? 1.6190 0.9463 1.4736 0.0473  -0.3311 -0.5761 658 TYR   A CB  
1932 N N   . SER   A 286 ? 1.4357 0.6763 1.3716 0.0471  -0.3200 -0.4837 659 SER   A N   
1933 C CA  . SER   A 286 ? 1.4905 0.6592 1.4636 0.0380  -0.3380 -0.4763 659 SER   A CA  
1934 C C   . SER   A 286 ? 1.4992 0.6357 1.4879 0.0639  -0.3318 -0.4661 659 SER   A C   
1935 O O   . SER   A 286 ? 1.7295 0.7991 1.7459 0.0637  -0.3479 -0.4651 659 SER   A O   
1936 C CB  . SER   A 286 ? 1.4034 0.5695 1.3969 0.0027  -0.3419 -0.4323 659 SER   A CB  
1937 N N   . GLY   A 287 ? 1.4326 0.6163 1.4037 0.0863  -0.3096 -0.4591 660 GLY   A N   
1938 C CA  . GLY   A 287 ? 1.4344 0.6008 1.4220 0.1065  -0.3019 -0.4374 660 GLY   A CA  
1939 C C   . GLY   A 287 ? 1.3547 0.5428 1.3493 0.0877  -0.2888 -0.3781 660 GLY   A C   
1940 O O   . GLY   A 287 ? 1.3454 0.5304 1.3502 0.1010  -0.2802 -0.3519 660 GLY   A O   
1941 N N   . TYR   A 288 ? 1.2117 0.4239 1.2006 0.0576  -0.2885 -0.3603 661 TYR   A N   
1942 C CA  . TYR   A 288 ? 1.2008 0.4247 1.2013 0.0352  -0.2811 -0.3100 661 TYR   A CA  
1943 C C   . TYR   A 288 ? 1.1822 0.4770 1.1580 0.0368  -0.2586 -0.2946 661 TYR   A C   
1944 O O   . TYR   A 288 ? 1.2370 0.5690 1.1925 0.0286  -0.2563 -0.3069 661 TYR   A O   
1945 C CB  . TYR   A 288 ? 1.1847 0.3873 1.2027 0.0002  -0.2967 -0.2984 661 TYR   A CB  
1946 C CG  . TYR   A 288 ? 1.1979 0.4135 1.2308 -0.0219 -0.2883 -0.2475 661 TYR   A CG  
1947 C CD1 . TYR   A 288 ? 1.1483 0.4239 1.1691 -0.0329 -0.2739 -0.2278 661 TYR   A CD1 
1948 C CD2 . TYR   A 288 ? 1.2298 0.3994 1.2868 -0.0292 -0.2938 -0.2187 661 TYR   A CD2 
1949 C CE1 . TYR   A 288 ? 1.1153 0.4065 1.1496 -0.0504 -0.2650 -0.1850 661 TYR   A CE1 
1950 C CE2 . TYR   A 288 ? 1.2178 0.4049 1.2856 -0.0488 -0.2844 -0.1734 661 TYR   A CE2 
1951 C CZ  . TYR   A 288 ? 1.1706 0.4200 1.2277 -0.0590 -0.2696 -0.1585 661 TYR   A CZ  
1952 O OH  . TYR   A 288 ? 1.2024 0.4699 1.2712 -0.0769 -0.2602 -0.1175 661 TYR   A OH  
1953 N N   . LYS   A 289 ? 1.0846 0.3970 1.0619 0.0463  -0.2429 -0.2659 662 LYS   A N   
1954 C CA  . LYS   A 289 ? 1.1400 0.5131 1.0962 0.0450  -0.2230 -0.2506 662 LYS   A CA  
1955 C C   . LYS   A 289 ? 0.9873 0.3724 0.9556 0.0309  -0.2138 -0.2049 662 LYS   A C   
1956 O O   . LYS   A 289 ? 0.9926 0.3464 0.9812 0.0286  -0.2180 -0.1831 662 LYS   A O   
1957 C CB  . LYS   A 289 ? 1.1638 0.5697 1.0991 0.0722  -0.2078 -0.2711 662 LYS   A CB  
1958 C CG  . LYS   A 289 ? 1.2513 0.6400 1.2012 0.0948  -0.2045 -0.2678 662 LYS   A CG  
1959 C CD  . LYS   A 289 ? 1.3303 0.7561 1.2647 0.1212  -0.1898 -0.2912 662 LYS   A CD  
1960 C CE  . LYS   A 289 ? 1.4327 0.8305 1.3872 0.1486  -0.1949 -0.3022 662 LYS   A CE  
1961 N NZ  . LYS   A 289 ? 1.3550 0.7949 1.3075 0.1640  -0.1769 -0.2911 662 LYS   A NZ  
1962 N N   . GLN   A 290 ? 1.0166 0.4475 0.9706 0.0206  -0.2022 -0.1911 663 GLN   A N   
1963 C CA  . GLN   A 290 ? 0.9426 0.3965 0.9026 0.0121  -0.1894 -0.1532 663 GLN   A CA  
1964 C C   . GLN   A 290 ? 0.8941 0.3844 0.8353 0.0302  -0.1708 -0.1529 663 GLN   A C   
1965 O O   . GLN   A 290 ? 0.9515 0.4692 0.8697 0.0364  -0.1648 -0.1719 663 GLN   A O   
1966 C CB  . GLN   A 290 ? 0.9280 0.4030 0.8906 -0.0115 -0.1920 -0.1398 663 GLN   A CB  
1967 C CG  . GLN   A 290 ? 1.0108 0.4505 0.9972 -0.0320 -0.2107 -0.1400 663 GLN   A CG  
1968 C CD  . GLN   A 290 ? 1.0680 0.5290 1.0543 -0.0505 -0.2193 -0.1464 663 GLN   A CD  
1969 O OE1 . GLN   A 290 ? 1.0256 0.5284 0.9954 -0.0497 -0.2112 -0.1433 663 GLN   A OE1 
1970 N NE2 . GLN   A 290 ? 1.2064 0.6370 1.2119 -0.0676 -0.2374 -0.1557 663 GLN   A NE2 
1971 N N   . VAL   A 291 ? 0.8892 0.3801 0.8399 0.0369  -0.1624 -0.1305 664 VAL   A N   
1972 C CA  . VAL   A 291 ? 0.8488 0.3753 0.7866 0.0512  -0.1449 -0.1270 664 VAL   A CA  
1973 C C   . VAL   A 291 ? 0.8502 0.3997 0.7917 0.0394  -0.1343 -0.0930 664 VAL   A C   
1974 O O   . VAL   A 291 ? 0.8592 0.3904 0.8180 0.0321  -0.1386 -0.0704 664 VAL   A O   
1975 C CB  . VAL   A 291 ? 0.8613 0.3715 0.8074 0.0744  -0.1460 -0.1373 664 VAL   A CB  
1976 C CG1 . VAL   A 291 ? 0.8216 0.3731 0.7566 0.0890  -0.1286 -0.1391 664 VAL   A CG1 
1977 C CG2 . VAL   A 291 ? 0.8898 0.3710 0.8371 0.0872  -0.1588 -0.1724 664 VAL   A CG2 
1978 N N   . GLN   A 292 ? 0.8171 0.4059 0.7412 0.0379  -0.1204 -0.0902 665 GLN   A N   
1979 C CA  . GLN   A 292 ? 0.7704 0.3841 0.6957 0.0299  -0.1091 -0.0639 665 GLN   A CA  
1980 C C   . GLN   A 292 ? 0.7539 0.3956 0.6671 0.0428  -0.0941 -0.0665 665 GLN   A C   
1981 O O   . GLN   A 292 ? 0.7738 0.4328 0.6690 0.0482  -0.0878 -0.0837 665 GLN   A O   
1982 C CB  . GLN   A 292 ? 0.7942 0.4264 0.7132 0.0146  -0.1081 -0.0562 665 GLN   A CB  
1983 C CG  . GLN   A 292 ? 0.7828 0.4326 0.7116 0.0046  -0.1006 -0.0291 665 GLN   A CG  
1984 C CD  . GLN   A 292 ? 0.8887 0.5527 0.8197 -0.0091 -0.1038 -0.0225 665 GLN   A CD  
1985 O OE1 . GLN   A 292 ? 0.8520 0.5101 0.7803 -0.0143 -0.1144 -0.0351 665 GLN   A OE1 
1986 N NE2 . GLN   A 292 ? 1.0192 0.7047 0.9562 -0.0143 -0.0952 -0.0038 665 GLN   A NE2 
1987 N N   . VAL   A 293 ? 0.7361 0.3825 0.6593 0.0472  -0.0889 -0.0502 666 VAL   A N   
1988 C CA  . VAL   A 293 ? 0.7619 0.4388 0.6771 0.0557  -0.0749 -0.0504 666 VAL   A CA  
1989 C C   . VAL   A 293 ? 0.7032 0.4035 0.6107 0.0428  -0.0652 -0.0349 666 VAL   A C   
1990 O O   . VAL   A 293 ? 0.7308 0.4255 0.6458 0.0309  -0.0690 -0.0194 666 VAL   A O   
1991 C CB  . VAL   A 293 ? 0.7656 0.4422 0.6938 0.0674  -0.0748 -0.0414 666 VAL   A CB  
1992 C CG1 . VAL   A 293 ? 0.8137 0.4647 0.7514 0.0840  -0.0858 -0.0574 666 VAL   A CG1 
1993 C CG2 . VAL   A 293 ? 0.7935 0.4638 0.7321 0.0568  -0.0773 -0.0133 666 VAL   A CG2 
1994 N N   . PRO   A 294 ? 0.6926 0.4199 0.5864 0.0446  -0.0525 -0.0394 667 PRO   A N   
1995 C CA  . PRO   A 294 ? 0.6579 0.4025 0.5448 0.0341  -0.0442 -0.0263 667 PRO   A CA  
1996 C C   . PRO   A 294 ? 0.6566 0.4041 0.5577 0.0299  -0.0434 -0.0063 667 PRO   A C   
1997 O O   . PRO   A 294 ? 0.6985 0.4480 0.6082 0.0367  -0.0430 -0.0019 667 PRO   A O   
1998 C CB  . PRO   A 294 ? 0.6536 0.4217 0.5275 0.0379  -0.0315 -0.0348 667 PRO   A CB  
1999 C CG  . PRO   A 294 ? 0.6568 0.4227 0.5243 0.0473  -0.0334 -0.0562 667 PRO   A CG  
2000 C CD  . PRO   A 294 ? 0.6710 0.4138 0.5568 0.0563  -0.0454 -0.0579 667 PRO   A CD  
2001 N N   . ARG   A 295 ? 0.6537 0.4041 0.5568 0.0195  -0.0436 0.0051  668 ARG   A N   
2002 C CA  . ARG   A 295 ? 0.7352 0.4930 0.6508 0.0142  -0.0419 0.0229  668 ARG   A CA  
2003 C C   . ARG   A 295 ? 0.7082 0.4832 0.6195 0.0082  -0.0350 0.0277  668 ARG   A C   
2004 O O   . ARG   A 295 ? 0.7102 0.5014 0.6233 0.0080  -0.0273 0.0347  668 ARG   A O   
2005 C CB  . ARG   A 295 ? 0.8297 0.5693 0.7601 0.0070  -0.0528 0.0317  668 ARG   A CB  
2006 C CG  . ARG   A 295 ? 0.8510 0.5986 0.7940 0.0000  -0.0511 0.0518  668 ARG   A CG  
2007 C CD  . ARG   A 295 ? 0.8292 0.5735 0.7741 0.0071  -0.0510 0.0604  668 ARG   A CD  
2008 N NE  . ARG   A 295 ? 0.8246 0.5927 0.7604 0.0149  -0.0409 0.0577  668 ARG   A NE  
2009 C CZ  . ARG   A 295 ? 0.8312 0.6250 0.7638 0.0107  -0.0311 0.0617  668 ARG   A CZ  
2010 N NH1 . ARG   A 295 ? 0.7160 0.5185 0.6559 0.0006  -0.0297 0.0728  668 ARG   A NH1 
2011 N NH2 . ARG   A 295 ? 0.6685 0.4799 0.5923 0.0165  -0.0228 0.0533  668 ARG   A NH2 
2012 N N   . GLY   A 296 ? 0.7136 0.4843 0.6193 0.0044  -0.0392 0.0231  669 GLY   A N   
2013 C CA  . GLY   A 296 ? 0.6697 0.4522 0.5713 0.0017  -0.0350 0.0266  669 GLY   A CA  
2014 C C   . GLY   A 296 ? 0.6806 0.4656 0.5629 0.0049  -0.0274 0.0193  669 GLY   A C   
2015 O O   . GLY   A 296 ? 0.6937 0.4767 0.5670 0.0086  -0.0246 0.0103  669 GLY   A O   
2016 N N   . ARG   A 297 ? 0.5643 0.3542 0.4421 0.0033  -0.0243 0.0232  670 ARG   A N   
2017 C CA  . ARG   A 297 ? 0.6176 0.4053 0.4762 0.0028  -0.0184 0.0199  670 ARG   A CA  
2018 C C   . ARG   A 297 ? 0.5702 0.3490 0.4097 0.0022  -0.0225 0.0126  670 ARG   A C   
2019 O O   . ARG   A 297 ? 0.5222 0.2941 0.3587 0.0017  -0.0328 0.0127  670 ARG   A O   
2020 C CB  . ARG   A 297 ? 0.6634 0.4491 0.5219 0.0023  -0.0201 0.0264  670 ARG   A CB  
2021 C CG  . ARG   A 297 ? 0.8517 0.6470 0.7199 0.0030  -0.0118 0.0288  670 ARG   A CG  
2022 C CD  . ARG   A 297 ? 1.0556 0.8447 0.9231 0.0051  -0.0139 0.0323  670 ARG   A CD  
2023 N NE  . ARG   A 297 ? 1.1196 0.8930 0.9674 0.0023  -0.0110 0.0326  670 ARG   A NE  
2024 C CZ  . ARG   A 297 ? 1.0552 0.8278 0.8967 -0.0022 -0.0013 0.0295  670 ARG   A CZ  
2025 N NH1 . ARG   A 297 ? 0.9423 0.6977 0.7726 -0.0051 -0.0004 0.0324  670 ARG   A NH1 
2026 N NH2 . ARG   A 297 ? 0.9484 0.7368 0.7969 -0.0039 0.0060  0.0241  670 ARG   A NH2 
2027 N N   . LEU   A 298 ? 0.5297 0.3129 0.3560 0.0018  -0.0141 0.0056  671 LEU   A N   
2028 C CA  . LEU   A 298 ? 0.5903 0.3715 0.3962 0.0012  -0.0149 -0.0032 671 LEU   A CA  
2029 C C   . LEU   A 298 ? 0.6301 0.4080 0.4119 -0.0052 -0.0112 0.0024  671 LEU   A C   
2030 O O   . LEU   A 298 ? 0.6978 0.4762 0.4575 -0.0072 -0.0115 -0.0025 671 LEU   A O   
2031 C CB  . LEU   A 298 ? 0.5812 0.3747 0.3893 0.0051  -0.0070 -0.0150 671 LEU   A CB  
2032 C CG  . LEU   A 298 ? 0.6479 0.4380 0.4748 0.0132  -0.0136 -0.0214 671 LEU   A CG  
2033 C CD1 . LEU   A 298 ? 0.6759 0.4793 0.5029 0.0202  -0.0071 -0.0355 671 LEU   A CD1 
2034 C CD2 . LEU   A 298 ? 0.6859 0.4603 0.5118 0.0140  -0.0268 -0.0256 671 LEU   A CD2 
2035 N N   . PHE   A 299 ? 0.6120 0.3861 0.3964 -0.0086 -0.0073 0.0126  672 PHE   A N   
2036 C CA  . PHE   A 299 ? 0.6272 0.3905 0.3895 -0.0149 -0.0063 0.0213  672 PHE   A CA  
2037 C C   . PHE   A 299 ? 0.6385 0.3897 0.4118 -0.0126 -0.0113 0.0317  672 PHE   A C   
2038 O O   . PHE   A 299 ? 0.6390 0.3961 0.4357 -0.0079 -0.0119 0.0306  672 PHE   A O   
2039 C CB  . PHE   A 299 ? 0.6790 0.4499 0.4279 -0.0240 0.0077  0.0196  672 PHE   A CB  
2040 C CG  . PHE   A 299 ? 0.6678 0.4501 0.4352 -0.0261 0.0178  0.0161  672 PHE   A CG  
2041 C CD1 . PHE   A 299 ? 0.7426 0.5227 0.5314 -0.0213 0.0150  0.0184  672 PHE   A CD1 
2042 C CD2 . PHE   A 299 ? 0.7343 0.5336 0.4970 -0.0336 0.0301  0.0097  672 PHE   A CD2 
2043 C CE1 . PHE   A 299 ? 0.7026 0.4949 0.5047 -0.0238 0.0233  0.0144  672 PHE   A CE1 
2044 C CE2 . PHE   A 299 ? 0.6649 0.4776 0.4447 -0.0361 0.0377  0.0056  672 PHE   A CE2 
2045 C CZ  . PHE   A 299 ? 0.6362 0.4442 0.4339 -0.0313 0.0337  0.0079  672 PHE   A CZ  
2046 N N   . ALA   A 300 ? 0.6659 0.4005 0.4210 -0.0153 -0.0154 0.0417  673 ALA   A N   
2047 C CA  . ALA   A 300 ? 0.6763 0.3967 0.4410 -0.0109 -0.0209 0.0500  673 ALA   A CA  
2048 C C   . ALA   A 300 ? 0.6890 0.3867 0.4271 -0.0173 -0.0216 0.0618  673 ALA   A C   
2049 O O   . ALA   A 300 ? 0.7547 0.4528 0.4675 -0.0256 -0.0180 0.0641  673 ALA   A O   
2050 C CB  . ALA   A 300 ? 0.6115 0.3354 0.3920 -0.0008 -0.0347 0.0509  673 ALA   A CB  
2051 N N   . PHE   A 301 ? 0.7358 0.4138 0.4798 -0.0139 -0.0253 0.0690  674 PHE   A N   
2052 C CA  . PHE   A 301 ? 0.7762 0.4264 0.4974 -0.0223 -0.0244 0.0815  674 PHE   A CA  
2053 C C   . PHE   A 301 ? 0.7768 0.4012 0.4985 -0.0109 -0.0399 0.0926  674 PHE   A C   
2054 O O   . PHE   A 301 ? 0.7619 0.3938 0.5094 0.0030  -0.0474 0.0869  674 PHE   A O   
2055 C CB  . PHE   A 301 ? 0.7673 0.4141 0.4976 -0.0318 -0.0110 0.0762  674 PHE   A CB  
2056 C CG  . PHE   A 301 ? 0.7852 0.4610 0.5187 -0.0409 0.0031  0.0648  674 PHE   A CG  
2057 C CD1 . PHE   A 301 ? 0.8620 0.5635 0.6202 -0.0333 0.0057  0.0517  674 PHE   A CD1 
2058 C CD2 . PHE   A 301 ? 0.8098 0.4894 0.5216 -0.0564 0.0131  0.0677  674 PHE   A CD2 
2059 C CE1 . PHE   A 301 ? 0.8382 0.5651 0.6001 -0.0386 0.0162  0.0418  674 PHE   A CE1 
2060 C CE2 . PHE   A 301 ? 0.8455 0.5558 0.5639 -0.0619 0.0252  0.0554  674 PHE   A CE2 
2061 C CZ  . PHE   A 301 ? 0.7829 0.5152 0.5266 -0.0517 0.0257  0.0423  674 PHE   A CZ  
2062 N N   . ASP   A 302 ? 0.7949 0.3894 0.4889 -0.0172 -0.0442 0.1089  675 ASP   A N   
2063 C CA  . ASP   A 302 ? 0.8758 0.4394 0.5698 -0.0054 -0.0598 0.1209  675 ASP   A CA  
2064 C C   . ASP   A 302 ? 0.9379 0.4798 0.6509 -0.0042 -0.0553 0.1162  675 ASP   A C   
2065 O O   . ASP   A 302 ? 0.8599 0.4150 0.5855 -0.0131 -0.0405 0.1035  675 ASP   A O   
2066 C CB  . ASP   A 302 ? 0.9048 0.4420 0.5598 -0.0120 -0.0683 0.1426  675 ASP   A CB  
2067 C CG  . ASP   A 302 ? 0.9396 0.4514 0.5710 -0.0327 -0.0566 0.1540  675 ASP   A CG  
2068 O OD1 . ASP   A 302 ? 0.9187 0.4448 0.5611 -0.0448 -0.0398 0.1420  675 ASP   A OD1 
2069 O OD2 . ASP   A 302 ? 1.0996 0.5782 0.7022 -0.0373 -0.0652 0.1757  675 ASP   A OD2 
2070 N N   . SER   A 303 ? 0.9812 0.4917 0.6985 0.0092  -0.0695 0.1242  676 SER   A N   
2071 C CA  . SER   A 303 ? 1.0245 0.5211 0.7692 0.0192  -0.0693 0.1129  676 SER   A CA  
2072 C C   . SER   A 303 ? 0.9866 0.4648 0.7256 0.0001  -0.0550 0.1097  676 SER   A C   
2073 O O   . SER   A 303 ? 0.9324 0.4221 0.6949 0.0015  -0.0466 0.0917  676 SER   A O   
2074 C CB  . SER   A 303 ? 1.1092 0.5705 0.8560 0.0375  -0.0885 0.1231  676 SER   A CB  
2075 O OG  . SER   A 303 ? 1.1063 0.5334 0.8162 0.0287  -0.0969 0.1478  676 SER   A OG  
2076 N N   . GLU   A 304 ? 1.0567 0.5104 0.7635 -0.0189 -0.0522 0.1273  677 GLU   A N   
2077 C CA  . GLU   A 304 ? 1.1821 0.6131 0.8817 -0.0403 -0.0407 0.1281  677 GLU   A CA  
2078 C C   . GLU   A 304 ? 1.0945 0.5613 0.7833 -0.0617 -0.0228 0.1244  677 GLU   A C   
2079 O O   . GLU   A 304 ? 1.1011 0.5581 0.7800 -0.0840 -0.0118 0.1275  677 GLU   A O   
2080 C CB  . GLU   A 304 ? 1.2839 0.6605 0.9544 -0.0499 -0.0496 0.1536  677 GLU   A CB  
2081 C CG  . GLU   A 304 ? 1.3990 0.7365 1.0743 -0.0259 -0.0714 0.1627  677 GLU   A CG  
2082 C CD  . GLU   A 304 ? 1.4285 0.7149 1.1165 -0.0236 -0.0767 0.1597  677 GLU   A CD  
2083 O OE1 . GLU   A 304 ? 1.3494 0.6046 1.0226 -0.0482 -0.0690 0.1681  677 GLU   A OE1 
2084 O OE2 . GLU   A 304 ? 1.4362 0.7149 1.1501 0.0025  -0.0886 0.1479  677 GLU   A OE2 
2085 N N   . GLY   A 305 ? 0.9723 0.4793 0.6620 -0.0551 -0.0211 0.1187  678 GLY   A N   
2086 C CA  . GLY   A 305 ? 0.9468 0.4904 0.6295 -0.0700 -0.0058 0.1123  678 GLY   A CA  
2087 C C   . GLY   A 305 ? 0.9315 0.4650 0.5789 -0.0917 0.0006  0.1296  678 GLY   A C   
2088 O O   . GLY   A 305 ? 0.9296 0.4822 0.5746 -0.1103 0.0162  0.1246  678 GLY   A O   
2089 N N   . ASN   A 306 ? 0.9520 0.4641 0.5715 -0.0889 -0.0109 0.1492  679 ASN   A N   
2090 C CA  . ASN   A 306 ? 0.9855 0.4978 0.5673 -0.1093 -0.0037 0.1657  679 ASN   A CA  
2091 C C   . ASN   A 306 ? 0.9355 0.4875 0.5031 -0.1049 -0.0020 0.1599  679 ASN   A C   
2092 O O   . ASN   A 306 ? 0.9245 0.4922 0.4640 -0.1215 0.0083  0.1664  679 ASN   A O   
2093 C CB  . ASN   A 306 ? 1.0927 0.5553 0.6454 -0.1131 -0.0166 0.1939  679 ASN   A CB  
2094 C CG  . ASN   A 306 ? 1.1048 0.5275 0.6661 -0.1262 -0.0134 0.1994  679 ASN   A CG  
2095 O OD1 . ASN   A 306 ? 1.1716 0.5982 0.7238 -0.1525 0.0023  0.2026  679 ASN   A OD1 
2096 N ND2 . ASN   A 306 ? 1.0955 0.4854 0.6787 -0.1081 -0.0273 0.1963  679 ASN   A ND2 
2097 N N   . TYR   A 307 ? 0.8892 0.4585 0.4766 -0.0835 -0.0119 0.1466  680 TYR   A N   
2098 C CA  . TYR   A 307 ? 0.8760 0.4772 0.4514 -0.0781 -0.0134 0.1392  680 TYR   A CA  
2099 C C   . TYR   A 307 ? 0.8272 0.4586 0.4378 -0.0651 -0.0115 0.1156  680 TYR   A C   
2100 O O   . TYR   A 307 ? 0.8207 0.4458 0.4619 -0.0544 -0.0158 0.1093  680 TYR   A O   
2101 C CB  . TYR   A 307 ? 0.9246 0.5084 0.4792 -0.0667 -0.0337 0.1540  680 TYR   A CB  
2102 C CG  . TYR   A 307 ? 1.0068 0.5620 0.5192 -0.0803 -0.0364 0.1808  680 TYR   A CG  
2103 C CD1 . TYR   A 307 ? 1.0415 0.6156 0.5156 -0.0946 -0.0285 0.1867  680 TYR   A CD1 
2104 C CD2 . TYR   A 307 ? 1.0663 0.5752 0.5763 -0.0795 -0.0462 0.2002  680 TYR   A CD2 
2105 C CE1 . TYR   A 307 ? 1.1227 0.6726 0.5549 -0.1099 -0.0295 0.2140  680 TYR   A CE1 
2106 C CE2 . TYR   A 307 ? 1.1195 0.5976 0.5889 -0.0936 -0.0494 0.2282  680 TYR   A CE2 
2107 C CZ  . TYR   A 307 ? 1.1491 0.6487 0.5783 -0.1101 -0.0404 0.2365  680 TYR   A CZ  
2108 O OH  . TYR   A 307 ? 1.2254 0.6985 0.6104 -0.1264 -0.0422 0.2665  680 TYR   A OH  
2109 N N   . MET   A 308 ? 0.8140 0.4777 0.4189 -0.0661 -0.0053 0.1028  681 MET   A N   
2110 C CA  . MET   A 308 ? 0.7512 0.4405 0.3867 -0.0556 -0.0034 0.0823  681 MET   A CA  
2111 C C   . MET   A 308 ? 0.7496 0.4532 0.3778 -0.0463 -0.0135 0.0746  681 MET   A C   
2112 O O   . MET   A 308 ? 0.8016 0.5154 0.4008 -0.0520 -0.0115 0.0742  681 MET   A O   
2113 C CB  . MET   A 308 ? 0.7469 0.4618 0.3910 -0.0648 0.0147  0.0692  681 MET   A CB  
2114 C CG  . MET   A 308 ? 0.7354 0.4736 0.4089 -0.0531 0.0153  0.0503  681 MET   A CG  
2115 S SD  . MET   A 308 ? 0.6979 0.4677 0.3838 -0.0608 0.0341  0.0355  681 MET   A SD  
2116 C CE  . MET   A 308 ? 0.7539 0.5452 0.4072 -0.0711 0.0442  0.0320  681 MET   A CE  
2117 N N   . LEU   A 309 ? 0.7104 0.4164 0.3657 -0.0330 -0.0240 0.0673  682 LEU   A N   
2118 C CA  . LEU   A 309 ? 0.7183 0.4378 0.3748 -0.0254 -0.0341 0.0566  682 LEU   A CA  
2119 C C   . LEU   A 309 ? 0.6974 0.4374 0.3740 -0.0236 -0.0254 0.0379  682 LEU   A C   
2120 O O   . LEU   A 309 ? 0.6454 0.3885 0.3481 -0.0218 -0.0189 0.0348  682 LEU   A O   
2121 C CB  . LEU   A 309 ? 0.6994 0.4105 0.3766 -0.0144 -0.0506 0.0611  682 LEU   A CB  
2122 C CG  . LEU   A 309 ? 0.7044 0.4281 0.3916 -0.0080 -0.0632 0.0502  682 LEU   A CG  
2123 C CD1 . LEU   A 309 ? 0.7265 0.4521 0.3801 -0.0097 -0.0730 0.0502  682 LEU   A CD1 
2124 C CD2 . LEU   A 309 ? 0.6963 0.4185 0.4132 0.0009  -0.0751 0.0544  682 LEU   A CD2 
2125 N N   . THR   A 310 ? 0.7136 0.4663 0.3773 -0.0225 -0.0272 0.0251  683 THR   A N   
2126 C CA  . THR   A 310 ? 0.6784 0.4471 0.3579 -0.0185 -0.0213 0.0061  683 THR   A CA  
2127 C C   . THR   A 310 ? 0.6947 0.4642 0.3740 -0.0123 -0.0352 -0.0060 683 THR   A C   
2128 O O   . THR   A 310 ? 0.6992 0.4638 0.3588 -0.0130 -0.0469 -0.0013 683 THR   A O   
2129 C CB  . THR   A 310 ? 0.6892 0.4760 0.3512 -0.0246 -0.0053 -0.0022 683 THR   A CB  
2130 O OG1 . THR   A 310 ? 0.6863 0.4775 0.3140 -0.0275 -0.0090 -0.0045 683 THR   A OG1 
2131 C CG2 . THR   A 310 ? 0.7109 0.4975 0.3694 -0.0351 0.0080  0.0099  683 THR   A CG2 
2132 N N   . CYS   A 311 ? 0.6944 0.4699 0.3936 -0.0066 -0.0344 -0.0223 684 CYS   A N   
2133 C CA  . CYS   A 311 ? 0.6882 0.4608 0.3911 -0.0017 -0.0477 -0.0370 684 CYS   A CA  
2134 C C   . CYS   A 311 ? 0.7337 0.5180 0.4073 -0.0012 -0.0452 -0.0543 684 CYS   A C   
2135 O O   . CYS   A 311 ? 0.7378 0.5368 0.3979 -0.0030 -0.0302 -0.0582 684 CYS   A O   
2136 C CB  . CYS   A 311 ? 0.6702 0.4388 0.4056 0.0041  -0.0485 -0.0465 684 CYS   A CB  
2137 S SG  . CYS   A 311 ? 0.6199 0.3818 0.3895 0.0033  -0.0488 -0.0286 684 CYS   A SG  
2138 N N   . SER   A 312 ? 0.7238 0.5046 0.3891 0.0007  -0.0602 -0.0664 685 SER   A N   
2139 C CA  . SER   A 312 ? 0.7412 0.5332 0.3845 0.0039  -0.0599 -0.0899 685 SER   A CA  
2140 C C   . SER   A 312 ? 0.8082 0.5882 0.4643 0.0076  -0.0786 -0.1065 685 SER   A C   
2141 O O   . SER   A 312 ? 0.8388 0.6062 0.5152 0.0049  -0.0915 -0.0959 685 SER   A O   
2142 C CB  . SER   A 312 ? 0.7726 0.5788 0.3709 -0.0023 -0.0569 -0.0851 685 SER   A CB  
2143 O OG  . SER   A 312 ? 0.7575 0.5579 0.3398 -0.0043 -0.0757 -0.0811 685 SER   A OG  
2144 N N   . ALA   A 313 ? 0.8079 0.5941 0.4510 0.0128  -0.0803 -0.1336 686 ALA   A N   
2145 C CA  . ALA   A 313 ? 0.8310 0.6031 0.4855 0.0152  -0.0986 -0.1533 686 ALA   A CA  
2146 C C   . ALA   A 313 ? 0.8498 0.6210 0.4927 0.0076  -0.1162 -0.1436 686 ALA   A C   
2147 O O   . ALA   A 313 ? 0.8347 0.5928 0.4992 0.0050  -0.1331 -0.1490 686 ALA   A O   
2148 C CB  . ALA   A 313 ? 0.8547 0.6363 0.4910 0.0232  -0.0965 -0.1864 686 ALA   A CB  
2149 N N   . THR   A 314 ? 0.8384 0.6236 0.4493 0.0034  -0.1130 -0.1273 687 THR   A N   
2150 C CA  . THR   A 314 ? 0.8892 0.6793 0.4788 -0.0005 -0.1312 -0.1248 687 THR   A CA  
2151 C C   . THR   A 314 ? 0.8777 0.6639 0.4757 -0.0041 -0.1369 -0.0939 687 THR   A C   
2152 O O   . THR   A 314 ? 0.8796 0.6694 0.4700 -0.0058 -0.1551 -0.0888 687 THR   A O   
2153 C CB  . THR   A 314 ? 0.9455 0.7558 0.4851 -0.0007 -0.1257 -0.1353 687 THR   A CB  
2154 O OG1 . THR   A 314 ? 0.9982 0.8088 0.5340 -0.0001 -0.1460 -0.1577 687 THR   A OG1 
2155 C CG2 . THR   A 314 ? 0.9810 0.8000 0.4862 -0.0061 -0.1211 -0.1073 687 THR   A CG2 
2156 N N   . GLY   A 315 ? 0.8177 0.5974 0.4338 -0.0040 -0.1223 -0.0755 688 GLY   A N   
2157 C CA  . GLY   A 315 ? 0.7924 0.5670 0.4191 -0.0051 -0.1256 -0.0490 688 GLY   A CA  
2158 C C   . GLY   A 315 ? 0.7796 0.5513 0.4018 -0.0063 -0.1057 -0.0325 688 GLY   A C   
2159 O O   . GLY   A 315 ? 0.7531 0.5301 0.3679 -0.0070 -0.0895 -0.0416 688 GLY   A O   
2160 N N   . GLY   A 316 ? 0.8119 0.5762 0.4393 -0.0062 -0.1081 -0.0098 689 GLY   A N   
2161 C CA  . GLY   A 316 ? 0.8041 0.5617 0.4309 -0.0086 -0.0916 0.0057  689 GLY   A CA  
2162 C C   . GLY   A 316 ? 0.8242 0.5856 0.4078 -0.0152 -0.0810 0.0114  689 GLY   A C   
2163 O O   . GLY   A 316 ? 0.8989 0.6635 0.4489 -0.0167 -0.0904 0.0147  689 GLY   A O   
2164 N N   . VAL   A 317 ? 0.8014 0.5646 0.3858 -0.0202 -0.0614 0.0134  690 VAL   A N   
2165 C CA  . VAL   A 317 ? 0.8156 0.5844 0.3624 -0.0299 -0.0490 0.0218  690 VAL   A CA  
2166 C C   . VAL   A 317 ? 0.7943 0.5492 0.3482 -0.0365 -0.0380 0.0408  690 VAL   A C   
2167 O O   . VAL   A 317 ? 0.7645 0.5202 0.3494 -0.0354 -0.0286 0.0360  690 VAL   A O   
2168 C CB  . VAL   A 317 ? 0.8560 0.6495 0.3920 -0.0320 -0.0347 -0.0001 690 VAL   A CB  
2169 C CG1 . VAL   A 317 ? 0.8948 0.7006 0.3949 -0.0450 -0.0181 0.0093  690 VAL   A CG1 
2170 C CG2 . VAL   A 317 ? 0.8407 0.6444 0.3662 -0.0253 -0.0472 -0.0213 690 VAL   A CG2 
2171 N N   . ILE   A 318 ? 0.8535 0.5945 0.3765 -0.0438 -0.0404 0.0627  691 ILE   A N   
2172 C CA  . ILE   A 318 ? 0.8695 0.5883 0.3971 -0.0501 -0.0349 0.0827  691 ILE   A CA  
2173 C C   . ILE   A 318 ? 0.8777 0.6024 0.3740 -0.0677 -0.0173 0.0915  691 ILE   A C   
2174 O O   . ILE   A 318 ? 0.9376 0.6719 0.3946 -0.0744 -0.0171 0.0962  691 ILE   A O   
2175 C CB  . ILE   A 318 ? 0.9026 0.5937 0.4244 -0.0435 -0.0544 0.1033  691 ILE   A CB  
2176 C CG1 . ILE   A 318 ? 0.8564 0.5477 0.4152 -0.0278 -0.0695 0.0945  691 ILE   A CG1 
2177 C CG2 . ILE   A 318 ? 0.9545 0.6167 0.4742 -0.0510 -0.0491 0.1241  691 ILE   A CG2 
2178 C CD1 . ILE   A 318 ? 0.8591 0.5287 0.4191 -0.0182 -0.0889 0.1120  691 ILE   A CD1 
2179 N N   . TYR   A 319 ? 0.8599 0.5814 0.3747 -0.0759 -0.0026 0.0932  692 TYR   A N   
2180 C CA  . TYR   A 319 ? 0.9012 0.6303 0.3950 -0.0956 0.0157  0.1014  692 TYR   A CA  
2181 C C   . TYR   A 319 ? 0.9255 0.6202 0.4237 -0.1051 0.0163  0.1224  692 TYR   A C   
2182 O O   . TYR   A 319 ? 0.9282 0.6066 0.4597 -0.0961 0.0109  0.1195  692 TYR   A O   
2183 C CB  . TYR   A 319 ? 0.8728 0.6358 0.3894 -0.0990 0.0345  0.0796  692 TYR   A CB  
2184 C CG  . TYR   A 319 ? 0.8781 0.6747 0.3976 -0.0885 0.0364  0.0539  692 TYR   A CG  
2185 C CD1 . TYR   A 319 ? 0.9181 0.7453 0.4077 -0.0964 0.0481  0.0461  692 TYR   A CD1 
2186 C CD2 . TYR   A 319 ? 0.8253 0.6241 0.3792 -0.0713 0.0282  0.0362  692 TYR   A CD2 
2187 C CE1 . TYR   A 319 ? 0.9147 0.7708 0.4096 -0.0847 0.0496  0.0188  692 TYR   A CE1 
2188 C CE2 . TYR   A 319 ? 0.8311 0.6546 0.3905 -0.0615 0.0294  0.0120  692 TYR   A CE2 
2189 C CZ  . TYR   A 319 ? 0.8534 0.7046 0.3843 -0.0670 0.0395  0.0018  692 TYR   A CZ  
2190 O OH  . TYR   A 319 ? 0.8461 0.7183 0.3840 -0.0548 0.0390  -0.0248 692 TYR   A OH  
2191 N N   . LYS   A 320 ? 1.0038 0.6912 0.4696 -0.1252 0.0254  0.1411  693 LYS   A N   
2192 C CA  . LYS   A 320 ? 1.1065 0.7612 0.5742 -0.1398 0.0292  0.1599  693 LYS   A CA  
2193 C C   . LYS   A 320 ? 1.0659 0.7435 0.5614 -0.1518 0.0490  0.1448  693 LYS   A C   
2194 O O   . LYS   A 320 ? 1.0984 0.8155 0.5874 -0.1624 0.0656  0.1340  693 LYS   A O   
2195 C CB  . LYS   A 320 ? 1.1879 0.8258 0.6071 -0.1598 0.0313  0.1883  693 LYS   A CB  
2196 C CG  . LYS   A 320 ? 1.2743 0.8661 0.6916 -0.1754 0.0310  0.2120  693 LYS   A CG  
2197 N N   . LEU   A 321 ? 1.0590 0.7143 0.5860 -0.1491 0.0464  0.1427  694 LEU   A N   
2198 C CA  . LEU   A 321 ? 1.1074 0.7814 0.6608 -0.1612 0.0623  0.1298  694 LEU   A CA  
2199 C C   . LEU   A 321 ? 1.2544 0.9072 0.7907 -0.1893 0.0717  0.1492  694 LEU   A C   
2200 O O   . LEU   A 321 ? 1.2925 0.9173 0.7938 -0.1987 0.0665  0.1736  694 LEU   A O   
2201 C CB  . LEU   A 321 ? 1.0207 0.6824 0.6132 -0.1450 0.0541  0.1173  694 LEU   A CB  
2202 C CG  . LEU   A 321 ? 0.9396 0.6197 0.5517 -0.1198 0.0448  0.1006  694 LEU   A CG  
2203 C CD1 . LEU   A 321 ? 0.9336 0.6019 0.5804 -0.1074 0.0385  0.0918  694 LEU   A CD1 
2204 C CD2 . LEU   A 321 ? 0.8849 0.6119 0.5034 -0.1186 0.0563  0.0816  694 LEU   A CD2 
2205 N N   . GLY   A 322 ? 1.4015 1.0670 0.9630 -0.2031 0.0842  0.1387  695 GLY   A N   
2206 C CA  . GLY   A 322 ? 1.5287 1.1673 1.0834 -0.2307 0.0910  0.1547  695 GLY   A CA  
2207 C C   . GLY   A 322 ? 1.6996 1.3736 1.2338 -0.2596 0.1115  0.1607  695 GLY   A C   
2208 O O   . GLY   A 322 ? 1.8632 1.5386 1.4061 -0.2854 0.1233  0.1633  695 GLY   A O   
2209 N N   . GLY   A 323 ? 1.7377 1.4420 1.2446 -0.2561 0.1159  0.1622  696 GLY   A N   
2210 C CA  . GLY   A 323 ? 1.8184 1.5667 1.3056 -0.2809 0.1371  0.1645  696 GLY   A CA  
2211 C C   . GLY   A 323 ? 1.8824 1.6885 1.4067 -0.2847 0.1539  0.1363  696 GLY   A C   
2212 O O   . GLY   A 323 ? 1.8928 1.7147 1.4502 -0.2610 0.1482  0.1125  696 GLY   A O   
2213 N N   . ASP   A 324 ? 1.9602 1.7973 1.4793 -0.3158 0.1741  0.1408  697 ASP   A N   
2214 C CA  . ASP   A 324 ? 1.8666 1.7746 1.4124 -0.3197 0.1926  0.1147  697 ASP   A CA  
2215 C C   . ASP   A 324 ? 1.8449 1.7999 1.3581 -0.3277 0.2082  0.1156  697 ASP   A C   
2216 O O   . ASP   A 324 ? 2.0011 2.0110 1.5212 -0.3483 0.2295  0.1076  697 ASP   A O   
2217 C CB  . ASP   A 324 ? 1.7613 1.6791 1.3349 -0.3476 0.2038  0.1132  697 ASP   A CB  
2218 N N   . GLU   A 325 ? 1.6305 1.5666 1.1082 -0.3118 0.1974  0.1244  698 GLU   A N   
2219 C CA  . GLU   A 325 ? 1.5571 1.5386 1.0020 -0.3132 0.2095  0.1201  698 GLU   A CA  
2220 C C   . GLU   A 325 ? 1.5554 1.5920 1.0297 -0.2860 0.2135  0.0813  698 GLU   A C   
2221 O O   . GLU   A 325 ? 1.5403 1.5670 1.0521 -0.2628 0.2016  0.0638  698 GLU   A O   
2222 C CB  . GLU   A 325 ? 1.4890 1.4285 0.8866 -0.3052 0.1934  0.1423  698 GLU   A CB  
2223 N N   . LYS   A 326 ? 1.5465 1.6406 1.0024 -0.2889 0.2300  0.0681  699 LYS   A N   
2224 C CA  . LYS   A 326 ? 1.5131 1.6652 0.9982 -0.2662 0.2371  0.0299  699 LYS   A CA  
2225 C C   . LYS   A 326 ? 1.5475 1.6755 1.0346 -0.2296 0.2159  0.0143  699 LYS   A C   
2226 O O   . LYS   A 326 ? 1.4157 1.5395 0.9427 -0.2069 0.2059  -0.0044 699 LYS   A O   
2227 C CB  . LYS   A 326 ? 1.5435 1.7647 1.0063 -0.2795 0.2614  0.0192  699 LYS   A CB  
2228 N N   . VAL   A 327 ? 1.6639 1.7787 1.1070 -0.2253 0.2090  0.0221  700 VAL   A N   
2229 C CA  . VAL   A 327 ? 1.6118 1.6929 1.0524 -0.1964 0.1858  0.0139  700 VAL   A CA  
2230 C C   . VAL   A 327 ? 1.5832 1.5965 1.0261 -0.1968 0.1658  0.0407  700 VAL   A C   
2231 O O   . VAL   A 327 ? 1.5992 1.5880 1.0292 -0.2203 0.1693  0.0683  700 VAL   A O   
2232 C CB  . VAL   A 327 ? 1.4447 1.5395 0.8374 -0.1926 0.1843  0.0110  700 VAL   A CB  
2233 N N   . LEU   A 328 ? 1.5057 1.4896 0.9668 -0.1708 0.1451  0.0315  701 LEU   A N   
2234 C CA  . LEU   A 328 ? 1.4371 1.3627 0.9030 -0.1669 0.1256  0.0526  701 LEU   A CA  
2235 C C   . LEU   A 328 ? 1.3982 1.2963 0.8224 -0.1634 0.1098  0.0690  701 LEU   A C   
2236 O O   . LEU   A 328 ? 1.3490 1.2666 0.7570 -0.1509 0.1055  0.0532  701 LEU   A O   
2237 C CB  . LEU   A 328 ? 1.4017 1.3168 0.9125 -0.1431 0.1135  0.0345  701 LEU   A CB  
2238 C CG  . LEU   A 328 ? 1.3438 1.2092 0.8710 -0.1390 0.0976  0.0512  701 LEU   A CG  
2239 C CD1 . LEU   A 328 ? 1.3718 1.2245 0.9078 -0.1597 0.1069  0.0665  701 LEU   A CD1 
2240 C CD2 . LEU   A 328 ? 1.2659 1.1292 0.8322 -0.1160 0.0871  0.0327  701 LEU   A CD2 
2241 N N   . GLU   A 329 ? 1.3813 1.2337 0.7893 -0.1735 0.0998  0.0998  702 GLU   A N   
2242 C CA  . GLU   A 329 ? 1.4464 1.2759 0.8079 -0.1758 0.0869  0.1221  702 GLU   A CA  
2243 C C   . GLU   A 329 ? 1.2930 1.0979 0.6654 -0.1500 0.0617  0.1162  702 GLU   A C   
2244 O O   . GLU   A 329 ? 1.2803 1.0456 0.6725 -0.1426 0.0473  0.1281  702 GLU   A O   
2245 C CB  . GLU   A 329 ? 1.4498 1.2407 0.7867 -0.1980 0.0868  0.1592  702 GLU   A CB  
2246 N N   . SER   A 330 ? 1.2140 1.0455 0.5747 -0.1370 0.0570  0.0956  703 SER   A N   
2247 C CA  . SER   A 330 ? 1.2103 1.0267 0.5804 -0.1153 0.0339  0.0865  703 SER   A CA  
2248 C C   . SER   A 330 ? 1.2244 1.0150 0.5545 -0.1163 0.0154  0.1121  703 SER   A C   
2249 O O   . SER   A 330 ? 1.2865 1.0963 0.5726 -0.1223 0.0165  0.1142  703 SER   A O   
2250 C CB  . SER   A 330 ? 1.2164 1.0687 0.5896 -0.1030 0.0357  0.0531  703 SER   A CB  
2251 O OG  . SER   A 330 ? 1.2041 1.0432 0.5782 -0.0868 0.0126  0.0462  703 SER   A OG  
2252 N N   . CYS   A 331 ? 1.2022 0.9529 0.5485 -0.1077 -0.0028 0.1288  704 CYS   A N   
2253 C CA  . CYS   A 331 ? 1.2449 0.9667 0.5557 -0.1091 -0.0204 0.1584  704 CYS   A CA  
2254 C C   . CYS   A 331 ? 1.1925 0.9075 0.5086 -0.0885 -0.0474 0.1531  704 CYS   A C   
2255 O O   . CYS   A 331 ? 1.2663 0.9731 0.5447 -0.0877 -0.0630 0.1707  704 CYS   A O   
2256 C CB  . CYS   A 331 ? 1.2959 0.9753 0.6126 -0.1178 -0.0207 0.1867  704 CYS   A CB  
2257 S SG  . CYS   A 331 ? 1.2415 0.8916 0.6175 -0.0982 -0.0341 0.1803  704 CYS   A SG  
2258 N N   . LEU   A 332 ? 1.1132 0.8339 0.4746 -0.0730 -0.0537 0.1299  705 LEU   A N   
2259 C CA  . LEU   A 332 ? 1.0949 0.8126 0.4647 -0.0565 -0.0788 0.1251  705 LEU   A CA  
2260 C C   . LEU   A 332 ? 1.0304 0.7691 0.4381 -0.0460 -0.0796 0.0925  705 LEU   A C   
2261 O O   . LEU   A 332 ? 1.0224 0.7633 0.4670 -0.0451 -0.0669 0.0803  705 LEU   A O   
2262 C CB  . LEU   A 332 ? 1.1025 0.7850 0.4917 -0.0480 -0.0942 0.1468  705 LEU   A CB  
2263 C CG  . LEU   A 332 ? 1.1096 0.7912 0.5169 -0.0302 -0.1205 0.1432  705 LEU   A CG  
2264 C CD1 . LEU   A 332 ? 1.2063 0.8995 0.5700 -0.0292 -0.1373 0.1483  705 LEU   A CD1 
2265 C CD2 . LEU   A 332 ? 1.1411 0.7912 0.5710 -0.0204 -0.1324 0.1625  705 LEU   A CD2 
2266 N N   . SER   A 333 ? 1.0025 0.7553 0.3993 -0.0387 -0.0962 0.0797  706 SER   A N   
2267 C CA  . SER   A 333 ? 1.0050 0.7738 0.4320 -0.0304 -0.1008 0.0498  706 SER   A CA  
2268 C C   . SER   A 333 ? 1.0115 0.7741 0.4577 -0.0196 -0.1268 0.0511  706 SER   A C   
2269 O O   . SER   A 333 ? 1.0752 0.8403 0.4908 -0.0179 -0.1441 0.0598  706 SER   A O   
2270 C CB  . SER   A 333 ? 1.0234 0.8190 0.4202 -0.0334 -0.0961 0.0269  706 SER   A CB  
2271 O OG  . SER   A 333 ? 1.0451 0.8546 0.4370 -0.0411 -0.0707 0.0186  706 SER   A OG  
2272 N N   . LEU   A 334 ? 0.9300 0.6882 0.4260 -0.0129 -0.1297 0.0424  707 LEU   A N   
2273 C CA  . LEU   A 334 ? 0.9103 0.6659 0.4311 -0.0039 -0.1520 0.0463  707 LEU   A CA  
2274 C C   . LEU   A 334 ? 0.9059 0.6795 0.4301 -0.0022 -0.1679 0.0233  707 LEU   A C   
2275 O O   . LEU   A 334 ? 0.8922 0.6712 0.4224 0.0031  -0.1898 0.0265  707 LEU   A O   
2276 C CB  . LEU   A 334 ? 0.8948 0.6416 0.4656 0.0005  -0.1468 0.0489  707 LEU   A CB  
2277 C CG  . LEU   A 334 ? 0.9298 0.6573 0.5011 -0.0008 -0.1330 0.0684  707 LEU   A CG  
2278 C CD1 . LEU   A 334 ? 0.8848 0.6084 0.5040 0.0053  -0.1309 0.0684  707 LEU   A CD1 
2279 C CD2 . LEU   A 334 ? 0.9753 0.6868 0.5136 0.0009  -0.1441 0.0931  707 LEU   A CD2 
2280 N N   . GLY   A 335 ? 0.9202 0.7032 0.4452 -0.0060 -0.1577 -0.0012 708 GLY   A N   
2281 C CA  . GLY   A 335 ? 0.9147 0.7108 0.4396 -0.0057 -0.1723 -0.0266 708 GLY   A CA  
2282 C C   . GLY   A 335 ? 0.9033 0.6991 0.4763 -0.0032 -0.1880 -0.0328 708 GLY   A C   
2283 O O   . GLY   A 335 ? 0.8542 0.6424 0.4630 -0.0011 -0.1842 -0.0200 708 GLY   A O   
2284 N N   . GLY   A 336 ? 0.9465 0.7528 0.5205 -0.0048 -0.2052 -0.0542 709 GLY   A N   
2285 C CA  . GLY   A 336 ? 0.9175 0.7291 0.5320 -0.0056 -0.2239 -0.0588 709 GLY   A CA  
2286 C C   . GLY   A 336 ? 0.9029 0.7061 0.5590 -0.0106 -0.2184 -0.0767 709 GLY   A C   
2287 O O   . GLY   A 336 ? 0.8780 0.6858 0.5718 -0.0145 -0.2308 -0.0792 709 GLY   A O   
2288 N N   . HIS   A 337 ? 0.8971 0.6889 0.5480 -0.0106 -0.2000 -0.0874 710 HIS   A N   
2289 C CA  . HIS   A 337 ? 0.8784 0.6574 0.5666 -0.0139 -0.1957 -0.1011 710 HIS   A CA  
2290 C C   . HIS   A 337 ? 0.9365 0.7109 0.6099 -0.0144 -0.2001 -0.1327 710 HIS   A C   
2291 O O   . HIS   A 337 ? 0.9434 0.7234 0.5794 -0.0100 -0.1912 -0.1421 710 HIS   A O   
2292 C CB  . HIS   A 337 ? 0.8192 0.5877 0.5221 -0.0110 -0.1731 -0.0884 710 HIS   A CB  
2293 C CG  . HIS   A 337 ? 0.7517 0.5222 0.4802 -0.0108 -0.1697 -0.0634 710 HIS   A CG  
2294 N ND1 . HIS   A 337 ? 0.6951 0.4640 0.4666 -0.0152 -0.1728 -0.0595 710 HIS   A ND1 
2295 C CD2 . HIS   A 337 ? 0.7316 0.5056 0.4486 -0.0069 -0.1634 -0.0423 710 HIS   A CD2 
2296 C CE1 . HIS   A 337 ? 0.7189 0.4943 0.5042 -0.0125 -0.1675 -0.0388 710 HIS   A CE1 
2297 N NE2 . HIS   A 337 ? 0.6938 0.4696 0.4472 -0.0067 -0.1625 -0.0286 710 HIS   A NE2 
2298 N N   . ARG   A 338 ? 0.9433 0.7078 0.6477 -0.0206 -0.2133 -0.1490 711 ARG   A N   
2299 C CA  . ARG   A 338 ? 1.0183 0.7718 0.7168 -0.0209 -0.2201 -0.1822 711 ARG   A CA  
2300 C C   . ARG   A 338 ? 0.9734 0.7012 0.7012 -0.0190 -0.2087 -0.1886 711 ARG   A C   
2301 O O   . ARG   A 338 ? 0.9610 0.6714 0.6948 -0.0185 -0.2153 -0.2151 711 ARG   A O   
2302 C CB  . ARG   A 338 ? 1.0700 0.8261 0.7828 -0.0308 -0.2461 -0.1976 711 ARG   A CB  
2303 C CG  . ARG   A 338 ? 1.0978 0.8811 0.7888 -0.0324 -0.2624 -0.1902 711 ARG   A CG  
2304 N N   . ALA   A 339 ? 0.9041 0.6286 0.6504 -0.0173 -0.1932 -0.1642 712 ALA   A N   
2305 C CA  . ALA   A 339 ? 0.8740 0.5771 0.6448 -0.0140 -0.1823 -0.1652 712 ALA   A CA  
2306 C C   . ALA   A 339 ? 0.8211 0.5331 0.5857 -0.0073 -0.1609 -0.1443 712 ALA   A C   
2307 O O   . ALA   A 339 ? 0.8121 0.5406 0.5652 -0.0087 -0.1574 -0.1251 712 ALA   A O   
2308 C CB  . ALA   A 339 ? 0.9034 0.5915 0.7165 -0.0252 -0.1919 -0.1560 712 ALA   A CB  
2309 N N   . PRO   A 340 ? 0.8089 0.5107 0.5801 0.0007  -0.1472 -0.1483 713 PRO   A N   
2310 C CA  . PRO   A 340 ? 0.8042 0.5180 0.5684 0.0060  -0.1275 -0.1316 713 PRO   A CA  
2311 C C   . PRO   A 340 ? 0.7367 0.4562 0.5176 0.0002  -0.1233 -0.1024 713 PRO   A C   
2312 O O   . PRO   A 340 ? 0.7027 0.4132 0.5135 -0.0058 -0.1302 -0.0932 713 PRO   A O   
2313 C CB  . PRO   A 340 ? 0.7829 0.4831 0.5627 0.0153  -0.1197 -0.1428 713 PRO   A CB  
2314 C CG  . PRO   A 340 ? 0.8258 0.5142 0.5983 0.0196  -0.1314 -0.1740 713 PRO   A CG  
2315 C CD  . PRO   A 340 ? 0.8582 0.5383 0.6402 0.0069  -0.1509 -0.1724 713 PRO   A CD  
2316 N N   . VAL   A 341 ? 0.7202 0.4551 0.4803 0.0014  -0.1123 -0.0889 714 VAL   A N   
2317 C CA  . VAL   A 341 ? 0.6722 0.4120 0.4452 -0.0010 -0.1055 -0.0645 714 VAL   A CA  
2318 C C   . VAL   A 341 ? 0.6506 0.3877 0.4390 0.0029  -0.0908 -0.0605 714 VAL   A C   
2319 O O   . VAL   A 341 ? 0.6661 0.4074 0.4410 0.0083  -0.0804 -0.0704 714 VAL   A O   
2320 C CB  . VAL   A 341 ? 0.6773 0.4283 0.4221 -0.0014 -0.1012 -0.0520 714 VAL   A CB  
2321 C CG1 . VAL   A 341 ? 0.6749 0.4277 0.4340 -0.0021 -0.0941 -0.0301 714 VAL   A CG1 
2322 C CG2 . VAL   A 341 ? 0.7221 0.4774 0.4503 -0.0038 -0.1180 -0.0543 714 VAL   A CG2 
2323 N N   . VAL   A 342 ? 0.6408 0.3750 0.4570 0.0002  -0.0901 -0.0463 715 VAL   A N   
2324 C CA  . VAL   A 342 ? 0.6301 0.3619 0.4620 0.0040  -0.0794 -0.0423 715 VAL   A CA  
2325 C C   . VAL   A 342 ? 0.5925 0.3353 0.4318 0.0025  -0.0693 -0.0236 715 VAL   A C   
2326 O O   . VAL   A 342 ? 0.5756 0.3210 0.4236 0.0056  -0.0599 -0.0198 715 VAL   A O   
2327 C CB  . VAL   A 342 ? 0.6219 0.3376 0.4803 0.0019  -0.0881 -0.0438 715 VAL   A CB  
2328 C CG1 . VAL   A 342 ? 0.6806 0.3806 0.5338 0.0044  -0.0988 -0.0655 715 VAL   A CG1 
2329 C CG2 . VAL   A 342 ? 0.6210 0.3393 0.5003 -0.0079 -0.0958 -0.0296 715 VAL   A CG2 
2330 N N   . THR   A 343 ? 0.6123 0.3616 0.4498 -0.0011 -0.0729 -0.0132 716 THR   A N   
2331 C CA  . THR   A 343 ? 0.5712 0.3292 0.4136 -0.0007 -0.0636 0.0006  716 THR   A CA  
2332 C C   . THR   A 343 ? 0.5975 0.3582 0.4284 -0.0010 -0.0694 0.0073  716 THR   A C   
2333 O O   . THR   A 343 ? 0.6114 0.3711 0.4370 -0.0022 -0.0825 0.0036  716 THR   A O   
2334 C CB  . THR   A 343 ? 0.5750 0.3380 0.4465 -0.0028 -0.0621 0.0096  716 THR   A CB  
2335 O OG1 . THR   A 343 ? 0.5930 0.3657 0.4671 -0.0010 -0.0516 0.0185  716 THR   A OG1 
2336 C CG2 . THR   A 343 ? 0.5829 0.3501 0.4736 -0.0081 -0.0739 0.0136  716 THR   A CG2 
2337 N N   . VAL   A 344 ? 0.5683 0.3309 0.3937 0.0005  -0.0608 0.0163  717 VAL   A N   
2338 C CA  . VAL   A 344 ? 0.5978 0.3571 0.4097 0.0021  -0.0666 0.0241  717 VAL   A CA  
2339 C C   . VAL   A 344 ? 0.6111 0.3731 0.4388 0.0054  -0.0617 0.0334  717 VAL   A C   
2340 O O   . VAL   A 344 ? 0.5678 0.3361 0.4109 0.0050  -0.0519 0.0330  717 VAL   A O   
2341 C CB  . VAL   A 344 ? 0.6242 0.3757 0.4017 0.0000  -0.0614 0.0237  717 VAL   A CB  
2342 C CG1 . VAL   A 344 ? 0.6505 0.4034 0.4100 -0.0016 -0.0661 0.0115  717 VAL   A CG1 
2343 C CG2 . VAL   A 344 ? 0.6287 0.3806 0.4035 -0.0025 -0.0448 0.0243  717 VAL   A CG2 
2344 N N   . ASP   A 345 ? 0.5997 0.3573 0.4232 0.0099  -0.0701 0.0409  718 ASP   A N   
2345 C CA  . ASP   A 345 ? 0.6111 0.3652 0.4428 0.0149  -0.0654 0.0474  718 ASP   A CA  
2346 C C   . ASP   A 345 ? 0.6451 0.3816 0.4557 0.0191  -0.0740 0.0566  718 ASP   A C   
2347 O O   . ASP   A 345 ? 0.6215 0.3553 0.4153 0.0191  -0.0855 0.0587  718 ASP   A O   
2348 C CB  . ASP   A 345 ? 0.6268 0.3995 0.4926 0.0199  -0.0677 0.0467  718 ASP   A CB  
2349 C CG  . ASP   A 345 ? 0.5995 0.3747 0.4783 0.0246  -0.0578 0.0471  718 ASP   A CG  
2350 O OD1 . ASP   A 345 ? 0.6045 0.3656 0.4679 0.0220  -0.0485 0.0472  718 ASP   A OD1 
2351 O OD2 . ASP   A 345 ? 0.6150 0.4091 0.5200 0.0299  -0.0591 0.0459  718 ASP   A OD2 
2352 N N   . TRP   A 346 ? 0.6451 0.3689 0.4569 0.0231  -0.0697 0.0618  719 TRP   A N   
2353 C CA  . TRP   A 346 ? 0.6823 0.3829 0.4760 0.0281  -0.0789 0.0731  719 TRP   A CA  
2354 C C   . TRP   A 346 ? 0.6668 0.3609 0.4820 0.0386  -0.0790 0.0735  719 TRP   A C   
2355 O O   . TRP   A 346 ? 0.6512 0.3420 0.4725 0.0351  -0.0660 0.0686  719 TRP   A O   
2356 C CB  . TRP   A 346 ? 0.6768 0.3570 0.4363 0.0168  -0.0702 0.0793  719 TRP   A CB  
2357 C CG  . TRP   A 346 ? 0.6996 0.3545 0.4303 0.0178  -0.0811 0.0947  719 TRP   A CG  
2358 C CD1 . TRP   A 346 ? 0.7134 0.3546 0.4477 0.0307  -0.0974 0.1043  719 TRP   A CD1 
2359 C CD2 . TRP   A 346 ? 0.7074 0.3488 0.3992 0.0052  -0.0764 0.1039  719 TRP   A CD2 
2360 N NE1 . TRP   A 346 ? 0.7208 0.3374 0.4188 0.0270  -0.1048 0.1207  719 TRP   A NE1 
2361 C CE2 . TRP   A 346 ? 0.7337 0.3509 0.4041 0.0101  -0.0913 0.1213  719 TRP   A CE2 
2362 C CE3 . TRP   A 346 ? 0.6924 0.3430 0.3663 -0.0089 -0.0614 0.0990  719 TRP   A CE3 
2363 C CZ2 . TRP   A 346 ? 0.8041 0.4050 0.4325 -0.0011 -0.0905 0.1361  719 TRP   A CZ2 
2364 C CZ3 . TRP   A 346 ? 0.7317 0.3713 0.3666 -0.0198 -0.0596 0.1108  719 TRP   A CZ3 
2365 C CH2 . TRP   A 346 ? 0.7874 0.4013 0.3983 -0.0173 -0.0733 0.1304  719 TRP   A CH2 
2366 N N   . SER   A 347 ? 0.6823 0.3790 0.5118 0.0524  -0.0939 0.0766  720 SER   A N   
2367 C CA  . SER   A 347 ? 0.7614 0.4523 0.6124 0.0659  -0.0954 0.0744  720 SER   A CA  
2368 C C   . SER   A 347 ? 0.8034 0.4633 0.6390 0.0766  -0.1114 0.0872  720 SER   A C   
2369 O O   . SER   A 347 ? 0.7683 0.4249 0.5858 0.0771  -0.1249 0.0969  720 SER   A O   
2370 C CB  . SER   A 347 ? 0.7574 0.4846 0.6469 0.0758  -0.0979 0.0646  720 SER   A CB  
2371 O OG  . SER   A 347 ? 0.8104 0.5352 0.7208 0.0901  -0.0971 0.0587  720 SER   A OG  
2372 N N   . THR   A 348 ? 0.9233 0.5581 0.7643 0.0848  -0.1104 0.0872  721 THR   A N   
2373 C CA  . THR   A 348 ? 1.0690 0.6651 0.8942 0.0953  -0.1261 0.1015  721 THR   A CA  
2374 C C   . THR   A 348 ? 1.0735 0.6687 0.9320 0.1178  -0.1331 0.0924  721 THR   A C   
2375 O O   . THR   A 348 ? 1.0017 0.5970 0.8771 0.1188  -0.1208 0.0789  721 THR   A O   
2376 C CB  . THR   A 348 ? 1.0579 0.6103 0.8476 0.0799  -0.1193 0.1140  721 THR   A CB  
2377 O OG1 . THR   A 348 ? 1.1891 0.7427 0.9903 0.0710  -0.1010 0.1008  721 THR   A OG1 
2378 C CG2 . THR   A 348 ? 0.9976 0.5524 0.7514 0.0610  -0.1153 0.1245  721 THR   A CG2 
2379 N N   . ALA   A 349 ? 1.2257 0.8239 1.0937 0.1366  -0.1537 0.0984  722 ALA   A N   
2380 C CA  . ALA   A 349 ? 1.2485 0.8586 1.1543 0.1622  -0.1629 0.0873  722 ALA   A CA  
2381 C C   . ALA   A 349 ? 1.3094 0.9000 1.2095 0.1816  -0.1893 0.1022  722 ALA   A C   
2382 O O   . ALA   A 349 ? 1.2088 0.8062 1.0890 0.1766  -0.2011 0.1153  722 ALA   A O   
2383 C CB  . ALA   A 349 ? 1.1849 0.8565 1.1281 0.1647  -0.1561 0.0704  722 ALA   A CB  
2384 N N   . MET   A 350 ? 1.4319 0.9985 1.3497 0.2050  -0.1996 0.0990  723 MET   A N   
2385 C CA  . MET   A 350 ? 1.4650 1.0069 1.3779 0.2268  -0.2269 0.1144  723 MET   A CA  
2386 C C   . MET   A 350 ? 1.5515 1.0441 1.4101 0.2105  -0.2341 0.1428  723 MET   A C   
2387 O O   . MET   A 350 ? 1.6239 1.1147 1.4654 0.2173  -0.2547 0.1599  723 MET   A O   
2388 C CB  . MET   A 350 ? 1.4327 1.0300 1.3726 0.2409  -0.2423 0.1103  723 MET   A CB  
2389 C CG  . MET   A 350 ? 1.4405 1.1008 1.4330 0.2496  -0.2314 0.0836  723 MET   A CG  
2390 S SD  . MET   A 350 ? 1.4716 1.1478 1.5158 0.2906  -0.2457 0.0669  723 MET   A SD  
2391 C CE  . MET   A 350 ? 1.4069 1.1734 1.5039 0.2892  -0.2298 0.0408  723 MET   A CE  
2392 N N   . ASP   A 351 ? 1.5770 1.0344 1.4086 0.1879  -0.2166 0.1474  724 ASP   A N   
2393 C CA  . ASP   A 351 ? 1.5665 0.9774 1.3470 0.1697  -0.2195 0.1741  724 ASP   A CA  
2394 C C   . ASP   A 351 ? 1.5051 0.9466 1.2582 0.1558  -0.2223 0.1845  724 ASP   A C   
2395 O O   . ASP   A 351 ? 1.7157 1.1318 1.4303 0.1524  -0.2361 0.2087  724 ASP   A O   
2396 C CB  . ASP   A 351 ? 1.5736 0.9263 1.3416 0.1877  -0.2424 0.1945  724 ASP   A CB  
2397 N N   . CYS   A 352 ? 1.3685 0.8628 1.1399 0.1470  -0.2088 0.1659  725 CYS   A N   
2398 C CA  . CYS   A 352 ? 1.2311 0.7601 0.9867 0.1377  -0.2131 0.1684  725 CYS   A CA  
2399 C C   . CYS   A 352 ? 1.0027 0.5683 0.7682 0.1187  -0.1903 0.1502  725 CYS   A C   
2400 O O   . CYS   A 352 ? 0.9831 0.5671 0.7823 0.1210  -0.1773 0.1326  725 CYS   A O   
2401 C CB  . CYS   A 352 ? 1.2732 0.8352 1.0559 0.1600  -0.2356 0.1646  725 CYS   A CB  
2402 S SG  . CYS   A 352 ? 1.2396 0.8574 1.0225 0.1478  -0.2374 0.1550  725 CYS   A SG  
2403 N N   . GLY   A 353 ? 0.9565 0.5331 0.6918 0.1012  -0.1863 0.1542  726 GLY   A N   
2404 C CA  . GLY   A 353 ? 0.9436 0.5453 0.6822 0.0832  -0.1652 0.1394  726 GLY   A CA  
2405 C C   . GLY   A 353 ? 0.9080 0.5539 0.6649 0.0834  -0.1705 0.1264  726 GLY   A C   
2406 O O   . GLY   A 353 ? 0.9103 0.5655 0.6531 0.0865  -0.1877 0.1319  726 GLY   A O   
2407 N N   . THR   A 354 ? 0.8503 0.5224 0.6367 0.0782  -0.1558 0.1096  727 THR   A N   
2408 C CA  . THR   A 354 ? 0.8258 0.5353 0.6311 0.0742  -0.1582 0.0974  727 THR   A CA  
2409 C C   . THR   A 354 ? 0.7598 0.4740 0.5536 0.0563  -0.1402 0.0889  727 THR   A C   
2410 O O   . THR   A 354 ? 0.7125 0.4269 0.5191 0.0517  -0.1233 0.0829  727 THR   A O   
2411 C CB  . THR   A 354 ? 0.8294 0.5672 0.6832 0.0850  -0.1583 0.0869  727 THR   A CB  
2412 O OG1 . THR   A 354 ? 0.8774 0.6147 0.7435 0.1042  -0.1769 0.0928  727 THR   A OG1 
2413 C CG2 . THR   A 354 ? 0.8557 0.6308 0.7329 0.0774  -0.1593 0.0756  727 THR   A CG2 
2414 N N   . CYS   A 355 ? 0.7370 0.4569 0.5077 0.0476  -0.1449 0.0868  728 CYS   A N   
2415 C CA  . CYS   A 355 ? 0.7383 0.4636 0.5010 0.0340  -0.1298 0.0764  728 CYS   A CA  
2416 C C   . CYS   A 355 ? 0.6819 0.4329 0.4689 0.0307  -0.1346 0.0627  728 CYS   A C   
2417 O O   . CYS   A 355 ? 0.6887 0.4504 0.4729 0.0320  -0.1512 0.0603  728 CYS   A O   
2418 C CB  . CYS   A 355 ? 0.8066 0.5189 0.5239 0.0254  -0.1281 0.0807  728 CYS   A CB  
2419 S SG  . CYS   A 355 ? 0.8048 0.4840 0.4907 0.0232  -0.1213 0.0998  728 CYS   A SG  
2420 N N   . LEU   A 356 ? 0.6398 0.3986 0.4473 0.0250  -0.1204 0.0543  729 LEU   A N   
2421 C CA  . LEU   A 356 ? 0.6425 0.4181 0.4704 0.0189  -0.1229 0.0430  729 LEU   A CA  
2422 C C   . LEU   A 356 ? 0.6527 0.4201 0.4591 0.0106  -0.1151 0.0337  729 LEU   A C   
2423 O O   . LEU   A 356 ? 0.6550 0.4139 0.4519 0.0083  -0.0997 0.0338  729 LEU   A O   
2424 C CB  . LEU   A 356 ? 0.6465 0.4364 0.5115 0.0185  -0.1137 0.0417  729 LEU   A CB  
2425 C CG  . LEU   A 356 ? 0.6907 0.4949 0.5816 0.0282  -0.1185 0.0471  729 LEU   A CG  
2426 C CD1 . LEU   A 356 ? 0.7257 0.5498 0.6498 0.0250  -0.1077 0.0445  729 LEU   A CD1 
2427 C CD2 . LEU   A 356 ? 0.7483 0.5667 0.6475 0.0325  -0.1386 0.0471  729 LEU   A CD2 
2428 N N   . THR   A 357 ? 0.6652 0.4376 0.4669 0.0067  -0.1267 0.0236  730 THR   A N   
2429 C CA  . THR   A 357 ? 0.6731 0.4402 0.4636 0.0010  -0.1212 0.0101  730 THR   A CA  
2430 C C   . THR   A 357 ? 0.6588 0.4325 0.4778 -0.0043 -0.1302 -0.0002 730 THR   A C   
2431 O O   . THR   A 357 ? 0.6449 0.4292 0.4752 -0.0057 -0.1463 -0.0017 730 THR   A O   
2432 C CB  . THR   A 357 ? 0.6933 0.4562 0.4428 0.0006  -0.1259 0.0052  730 THR   A CB  
2433 O OG1 . THR   A 357 ? 0.7192 0.4902 0.4663 0.0019  -0.1460 0.0049  730 THR   A OG1 
2434 C CG2 . THR   A 357 ? 0.7100 0.4644 0.4316 0.0021  -0.1154 0.0181  730 THR   A CG2 
2435 N N   . ALA   A 358 ? 0.6441 0.4113 0.4753 -0.0075 -0.1203 -0.0063 731 ALA   A N   
2436 C CA  . ALA   A 358 ? 0.6312 0.3987 0.4924 -0.0145 -0.1262 -0.0116 731 ALA   A CA  
2437 C C   . ALA   A 358 ? 0.6382 0.3896 0.4905 -0.0159 -0.1260 -0.0278 731 ALA   A C   
2438 O O   . ALA   A 358 ? 0.6202 0.3645 0.4594 -0.0110 -0.1134 -0.0305 731 ALA   A O   
2439 C CB  . ALA   A 358 ? 0.6120 0.3858 0.5008 -0.0160 -0.1157 0.0004  731 ALA   A CB  
2440 N N   . SER   A 359 ? 0.6577 0.4045 0.5193 -0.0223 -0.1407 -0.0399 732 SER   A N   
2441 C CA  . SER   A 359 ? 0.6754 0.4052 0.5259 -0.0218 -0.1447 -0.0602 732 SER   A CA  
2442 C C   . SER   A 359 ? 0.7089 0.4220 0.5903 -0.0299 -0.1505 -0.0639 732 SER   A C   
2443 O O   . SER   A 359 ? 0.7041 0.4230 0.6142 -0.0388 -0.1525 -0.0504 732 SER   A O   
2444 C CB  . SER   A 359 ? 0.7214 0.4563 0.5487 -0.0222 -0.1591 -0.0752 732 SER   A CB  
2445 O OG  . SER   A 359 ? 0.7180 0.4653 0.5635 -0.0301 -0.1750 -0.0713 732 SER   A OG  
2446 N N   . MET   A 360 ? 0.7209 0.4131 0.5959 -0.0269 -0.1537 -0.0830 733 MET   A N   
2447 C CA  . MET   A 360 ? 0.7530 0.4200 0.6531 -0.0320 -0.1578 -0.0855 733 MET   A CA  
2448 C C   . MET   A 360 ? 0.7805 0.4405 0.7031 -0.0477 -0.1760 -0.0903 733 MET   A C   
2449 O O   . MET   A 360 ? 0.7878 0.4287 0.7364 -0.0572 -0.1796 -0.0843 733 MET   A O   
2450 C CB  . MET   A 360 ? 0.7551 0.4006 0.6417 -0.0205 -0.1565 -0.1071 733 MET   A CB  
2451 C CG  . MET   A 360 ? 0.7192 0.3724 0.5941 -0.0075 -0.1385 -0.1007 733 MET   A CG  
2452 S SD  . MET   A 360 ? 0.7475 0.3799 0.6155 0.0082  -0.1373 -0.1266 733 MET   A SD  
2453 C CE  . MET   A 360 ? 0.7611 0.3544 0.6642 0.0048  -0.1470 -0.1200 733 MET   A CE  
2454 N N   . ASP   A 361 ? 0.7903 0.4680 0.7033 -0.0516 -0.1875 -0.0987 734 ASP   A N   
2455 C CA  . ASP   A 361 ? 0.7740 0.4552 0.7102 -0.0679 -0.2054 -0.1029 734 ASP   A CA  
2456 C C   . ASP   A 361 ? 0.7462 0.4540 0.7104 -0.0776 -0.2025 -0.0784 734 ASP   A C   
2457 O O   . ASP   A 361 ? 0.7677 0.4888 0.7540 -0.0914 -0.2160 -0.0798 734 ASP   A O   
2458 C CB  . ASP   A 361 ? 0.7812 0.4761 0.6942 -0.0664 -0.2202 -0.1224 734 ASP   A CB  
2459 C CG  . ASP   A 361 ? 0.7806 0.5029 0.6650 -0.0548 -0.2136 -0.1127 734 ASP   A CG  
2460 O OD1 . ASP   A 361 ? 0.7570 0.4878 0.6451 -0.0497 -0.1984 -0.0914 734 ASP   A OD1 
2461 O OD2 . ASP   A 361 ? 0.7988 0.5310 0.6546 -0.0508 -0.2233 -0.1265 734 ASP   A OD2 
2462 N N   . GLY   A 362 ? 0.7374 0.4577 0.7006 -0.0699 -0.1853 -0.0584 735 GLY   A N   
2463 C CA  . GLY   A 362 ? 0.7120 0.4610 0.7008 -0.0763 -0.1810 -0.0382 735 GLY   A CA  
2464 C C   . GLY   A 362 ? 0.7057 0.4853 0.6842 -0.0680 -0.1844 -0.0352 735 GLY   A C   
2465 O O   . GLY   A 362 ? 0.6789 0.4854 0.6779 -0.0689 -0.1806 -0.0210 735 GLY   A O   
2466 N N   . LYS   A 363 ? 0.7137 0.4897 0.6599 -0.0589 -0.1915 -0.0482 736 LYS   A N   
2467 C CA  . LYS   A 363 ? 0.7208 0.5207 0.6548 -0.0512 -0.1986 -0.0441 736 LYS   A CA  
2468 C C   . LYS   A 363 ? 0.6858 0.4874 0.6019 -0.0376 -0.1823 -0.0294 736 LYS   A C   
2469 O O   . LYS   A 363 ? 0.7124 0.4960 0.6089 -0.0323 -0.1685 -0.0299 736 LYS   A O   
2470 C CB  . LYS   A 363 ? 0.7580 0.5545 0.6622 -0.0492 -0.2144 -0.0624 736 LYS   A CB  
2471 C CG  . LYS   A 363 ? 0.7877 0.5918 0.7128 -0.0627 -0.2350 -0.0768 736 LYS   A CG  
2472 C CD  . LYS   A 363 ? 0.8651 0.6633 0.7583 -0.0614 -0.2503 -0.0996 736 LYS   A CD  
2473 N N   . ILE   A 364 ? 0.6540 0.4780 0.5801 -0.0320 -0.1846 -0.0173 737 ILE   A N   
2474 C CA  . ILE   A 364 ? 0.6531 0.4762 0.5627 -0.0194 -0.1727 -0.0045 737 ILE   A CA  
2475 C C   . ILE   A 364 ? 0.6932 0.5253 0.5832 -0.0102 -0.1867 -0.0016 737 ILE   A C   
2476 O O   . ILE   A 364 ? 0.7136 0.5682 0.6243 -0.0099 -0.2018 -0.0010 737 ILE   A O   
2477 C CB  . ILE   A 364 ? 0.6401 0.4781 0.5814 -0.0184 -0.1611 0.0079  737 ILE   A CB  
2478 C CG1 . ILE   A 364 ? 0.5882 0.4175 0.5453 -0.0277 -0.1480 0.0085  737 ILE   A CG1 
2479 C CG2 . ILE   A 364 ? 0.6209 0.4561 0.5470 -0.0050 -0.1514 0.0186  737 ILE   A CG2 
2480 C CD1 . ILE   A 364 ? 0.5599 0.4108 0.5493 -0.0299 -0.1382 0.0197  737 ILE   A CD1 
2481 N N   . LYS   A 365 ? 0.7196 0.5355 0.5695 -0.0033 -0.1822 0.0008  738 LYS   A N   
2482 C CA  . LYS   A 365 ? 0.7379 0.5569 0.5629 0.0055  -0.1947 0.0081  738 LYS   A CA  
2483 C C   . LYS   A 365 ? 0.7448 0.5590 0.5719 0.0158  -0.1854 0.0251  738 LYS   A C   
2484 O O   . LYS   A 365 ? 0.6945 0.4937 0.5146 0.0155  -0.1669 0.0292  738 LYS   A O   
2485 C CB  . LYS   A 365 ? 0.7697 0.5751 0.5459 0.0050  -0.1961 0.0026  738 LYS   A CB  
2486 C CG  . LYS   A 365 ? 0.8374 0.6499 0.6035 -0.0015 -0.2119 -0.0160 738 LYS   A CG  
2487 C CD  . LYS   A 365 ? 0.8812 0.7166 0.6762 -0.0033 -0.2340 -0.0199 738 LYS   A CD  
2488 C CE  . LYS   A 365 ? 0.9570 0.8029 0.7271 -0.0047 -0.2559 -0.0320 738 LYS   A CE  
2489 N NZ  . LYS   A 365 ? 1.0036 0.8370 0.7410 -0.0101 -0.2523 -0.0504 738 LYS   A NZ  
2490 N N   . LEU   A 366 ? 0.7083 0.5353 0.5461 0.0256  -0.1998 0.0334  739 LEU   A N   
2491 C CA  . LEU   A 366 ? 0.7345 0.5521 0.5714 0.0378  -0.1948 0.0480  739 LEU   A CA  
2492 C C   . LEU   A 366 ? 0.7941 0.5972 0.5911 0.0456  -0.2084 0.0591  739 LEU   A C   
2493 O O   . LEU   A 366 ? 0.8203 0.6381 0.6161 0.0506  -0.2299 0.0591  739 LEU   A O   
2494 C CB  . LEU   A 366 ? 0.7264 0.5703 0.6104 0.0454  -0.1998 0.0485  739 LEU   A CB  
2495 C CG  . LEU   A 366 ? 0.7462 0.5824 0.6401 0.0596  -0.1928 0.0584  739 LEU   A CG  
2496 C CD1 . LEU   A 366 ? 0.7165 0.5832 0.6592 0.0606  -0.1859 0.0525  739 LEU   A CD1 
2497 C CD2 . LEU   A 366 ? 0.7850 0.6147 0.6667 0.0767  -0.2123 0.0696  739 LEU   A CD2 
2498 N N   . THR   A 367 ? 0.7897 0.5653 0.5519 0.0442  -0.1957 0.0683  740 THR   A N   
2499 C CA  . THR   A 367 ? 0.8376 0.5950 0.5565 0.0484  -0.2053 0.0829  740 THR   A CA  
2500 C C   . THR   A 367 ? 0.8603 0.5963 0.5828 0.0600  -0.2041 0.0999  740 THR   A C   
2501 O O   . THR   A 367 ? 0.8134 0.5354 0.5447 0.0575  -0.1856 0.1006  740 THR   A O   
2502 C CB  . THR   A 367 ? 0.8412 0.5847 0.5173 0.0359  -0.1914 0.0814  740 THR   A CB  
2503 O OG1 . THR   A 367 ? 0.8396 0.6001 0.5187 0.0271  -0.1904 0.0615  740 THR   A OG1 
2504 C CG2 . THR   A 367 ? 0.9134 0.6439 0.5400 0.0369  -0.2022 0.0969  740 THR   A CG2 
2505 N N   . THR   A 368 ? 0.8887 0.6208 0.6032 0.0733  -0.2255 0.1129  741 THR   A N   
2506 C CA  . THR   A 368 ? 0.8933 0.6011 0.6127 0.0874  -0.2290 0.1284  741 THR   A CA  
2507 C C   . THR   A 368 ? 0.9144 0.5850 0.5809 0.0835  -0.2300 0.1496  741 THR   A C   
2508 O O   . THR   A 368 ? 0.9036 0.5748 0.5359 0.0836  -0.2463 0.1591  741 THR   A O   
2509 C CB  . THR   A 368 ? 0.8983 0.6260 0.6481 0.1071  -0.2531 0.1294  741 THR   A CB  
2510 O OG1 . THR   A 368 ? 0.8457 0.6091 0.6445 0.1058  -0.2467 0.1105  741 THR   A OG1 
2511 C CG2 . THR   A 368 ? 0.9211 0.6210 0.6776 0.1256  -0.2596 0.1438  741 THR   A CG2 
2512 N N   . LEU   A 369 ? 0.9376 0.5773 0.5986 0.0791  -0.2129 0.1570  742 LEU   A N   
2513 C CA  . LEU   A 369 ? 1.0470 0.6494 0.6611 0.0700  -0.2084 0.1778  742 LEU   A CA  
2514 C C   . LEU   A 369 ? 1.1229 0.6867 0.7424 0.0837  -0.2169 0.1949  742 LEU   A C   
2515 O O   . LEU   A 369 ? 1.1093 0.6710 0.7686 0.0937  -0.2119 0.1852  742 LEU   A O   
2516 C CB  . LEU   A 369 ? 1.0167 0.6140 0.6195 0.0498  -0.1806 0.1713  742 LEU   A CB  
2517 C CG  . LEU   A 369 ? 0.9642 0.5924 0.5574 0.0362  -0.1697 0.1543  742 LEU   A CG  
2518 C CD1 . LEU   A 369 ? 0.9554 0.5755 0.5351 0.0188  -0.1441 0.1520  742 LEU   A CD1 
2519 C CD2 . LEU   A 369 ? 0.9939 0.6331 0.5482 0.0339  -0.1843 0.1593  742 LEU   A CD2 
2520 N N   . LEU   A 370 ? 1.2354 0.7665 0.8119 0.0827  -0.2285 0.2205  743 LEU   A N   
2521 C CA  . LEU   A 370 ? 1.2979 0.7794 0.8697 0.0899  -0.2333 0.2399  743 LEU   A CA  
2522 C C   . LEU   A 370 ? 1.2878 0.7373 0.8122 0.0654  -0.2179 0.2583  743 LEU   A C   
2523 O O   . LEU   A 370 ? 1.3392 0.8031 0.8216 0.0497  -0.2146 0.2651  743 LEU   A O   
2524 C CB  . LEU   A 370 ? 1.4666 0.9372 1.0348 0.1135  -0.2654 0.2565  743 LEU   A CB  
2525 C CG  . LEU   A 370 ? 1.6051 1.0312 1.1918 0.1337  -0.2776 0.2681  743 LEU   A CG  
2526 C CD1 . LEU   A 370 ? 1.6391 1.0913 1.2732 0.1645  -0.2988 0.2557  743 LEU   A CD1 
2527 C CD2 . LEU   A 370 ? 1.7081 1.0818 1.2445 0.1320  -0.2929 0.3041  743 LEU   A CD2 
2528 N N   . ALA   A 371 ? 1.4029 0.8135 0.9356 0.0609  -0.2071 0.2634  744 ALA   A N   
2529 C CA  . ALA   A 371 ? 1.5350 0.9110 1.0294 0.0363  -0.1926 0.2822  744 ALA   A CA  
2530 C C   . ALA   A 371 ? 1.5963 0.9238 1.0495 0.0386  -0.2125 0.3184  744 ALA   A C   
2531 O O   . ALA   A 371 ? 1.5478 0.8785 0.9918 0.0569  -0.2374 0.3291  744 ALA   A O   
2532 C CB  . ALA   A 371 ? 1.5232 0.8796 1.0473 0.0300  -0.1747 0.2701  744 ALA   A CB  
2533 N N   . HIS   A 372 ? 1.7452 1.0293 1.1715 0.0176  -0.2017 0.3385  745 HIS   A N   
2534 C CA  . HIS   A 372 ? 1.8400 1.0696 1.2256 0.0163  -0.2193 0.3767  745 HIS   A CA  
2535 C C   . HIS   A 372 ? 1.8181 0.9953 1.1971 -0.0053 -0.2049 0.3899  745 HIS   A C   
2536 O O   . HIS   A 372 ? 1.9411 1.0700 1.2779 -0.0156 -0.2149 0.4261  745 HIS   A O   
2537 C CB  . HIS   A 372 ? 1.8749 1.1235 1.2030 0.0036  -0.2240 0.3979  745 HIS   A CB  
2538 C C5  . A1BLV B .   ? 0.6716 1.1555 0.7518 0.0431  0.1438  -0.0475 801 A1BLV A C5  
2539 C C7  . A1BLV B .   ? 0.5660 0.9425 0.6476 0.0692  0.1170  -0.0695 801 A1BLV A C7  
2540 C C8  . A1BLV B .   ? 0.5581 0.9201 0.6428 0.0934  0.1148  -0.1036 801 A1BLV A C8  
2541 C C10 . A1BLV B .   ? 0.5529 0.8179 0.6191 0.0774  0.0918  -0.0698 801 A1BLV A C10 
2542 C C13 . A1BLV B .   ? 0.5029 0.7357 0.5433 0.0399  0.0849  -0.0158 801 A1BLV A C13 
2543 C C15 . A1BLV B .   ? 0.5230 0.7288 0.5756 0.0724  0.0789  -0.0579 801 A1BLV A C15 
2544 C C20 . A1BLV B .   ? 0.8598 1.4719 0.9130 -0.0139 0.1795  0.0132  801 A1BLV A C20 
2545 C C21 . A1BLV B .   ? 0.9840 1.6441 1.0563 -0.0337 0.1899  0.0334  801 A1BLV A C21 
2546 C C22 . A1BLV B .   ? 1.0658 1.7583 1.1156 -0.0576 0.2012  0.0621  801 A1BLV A C22 
2547 C C24 . A1BLV B .   ? 1.2189 1.9853 1.3363 -0.0814 0.2131  0.0759  801 A1BLV A C24 
2548 C C26 . A1BLV B .   ? 1.2846 2.1450 1.3696 -0.1212 0.2443  0.1148  801 A1BLV A C26 
2549 C C28 . A1BLV B .   ? 0.9753 1.6525 0.9824 -0.0590 0.2005  0.0699  801 A1BLV A C28 
2550 C C1  . A1BLV B .   ? 0.6683 1.2243 0.8613 0.0620  0.1377  -0.0624 801 A1BLV A C1  
2551 N N2  . A1BLV B .   ? 0.6640 1.2491 0.8346 0.0378  0.1517  -0.0418 801 A1BLV A N2  
2552 C C3  . A1BLV B .   ? 0.6799 1.2384 0.8118 0.0323  0.1533  -0.0359 801 A1BLV A C3  
2553 N N4  . A1BLV B .   ? 0.6660 1.1677 0.7816 0.0479  0.1419  -0.0504 801 A1BLV A N4  
2554 N N6  . A1BLV B .   ? 0.6083 1.0334 0.6740 0.0548  0.1317  -0.0595 801 A1BLV A N6  
2555 C C9  . A1BLV B .   ? 0.5603 0.8495 0.6421 0.0988  0.0969  -0.1009 801 A1BLV A C9  
2556 C C11 . A1BLV B .   ? 0.5430 0.8532 0.6082 0.0614  0.1023  -0.0524 801 A1BLV A C11 
2557 C C12 . A1BLV B .   ? 0.5436 0.8347 0.5954 0.0420  0.0982  -0.0242 801 A1BLV A C12 
2558 C C14 . A1BLV B .   ? 0.5094 0.7024 0.5494 0.0542  0.0761  -0.0323 801 A1BLV A C14 
2559 C C16 . A1BLV B .   ? 0.6077 0.7664 0.6615 0.0863  0.0679  -0.0711 801 A1BLV A C16 
2560 N N17 . A1BLV B .   ? 0.6282 0.7490 0.6824 0.0969  0.0593  -0.0807 801 A1BLV A N17 
2561 C C18 . A1BLV B .   ? 0.7363 1.2571 0.7951 0.0249  0.1560  -0.0296 801 A1BLV A C18 
2562 C C19 . A1BLV B .   ? 0.7503 1.3253 0.8259 0.0091  0.1673  -0.0128 801 A1BLV A C19 
2563 N N23 . A1BLV B .   ? 1.1990 1.9439 1.2691 -0.0803 0.2135  0.0824  801 A1BLV A N23 
2564 C C25 . A1BLV B .   ? 1.2358 2.0935 1.3652 -0.0976 0.2368  0.0812  801 A1BLV A C25 
2565 C C27 . A1BLV B .   ? 1.2249 2.0152 1.2719 -0.1056 0.2287  0.1112  801 A1BLV A C27 
2566 C C29 . A1BLV B .   ? 0.9340 1.5679 0.9247 -0.0385 0.1898  0.0476  801 A1BLV A C29 
2567 C C30 . A1BLV B .   ? 0.9133 1.5141 0.9268 -0.0174 0.1801  0.0198  801 A1BLV A C30 
2568 N N31 . A1BLV B .   ? 0.7421 1.3374 0.8556 0.0118  0.1666  -0.0167 801 A1BLV A N31 
# 
