data_9MIG
# 
_entry.id   9MIG 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9MIG         pdb_00009mig 10.2210/pdb9mig/pdb 
WWPDB D_1000291047 ?            ?                   
EMDB  EMD-48289    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-02-26 ? 
2 'EM metadata'     1 0 2025-02-26 ? 
3 'Additional map'  1 0 2025-02-26 1 
4 'Half map'        1 0 2025-02-26 1 
5 'Half map'        1 0 2025-02-26 2 
6 Image             1 0 2025-02-26 ? 
7 'Primary map'     1 0 2025-02-26 ? 
8 'Structure model' 1 1 2025-03-12 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Additional map'  repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 'Half map'        repository 'Initial release' ? ? 
6 6 Image             repository 'Initial release' ? ? 
7 7 'Primary map'     repository 'Initial release' ? ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 8 'Structure model' 'Data collection'     
2 8 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 8 'Structure model' citation        
2 8 'Structure model' citation_author 
3 8 'Structure model' em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 8 'Structure model' '_citation.journal_volume'          
2 8 'Structure model' '_citation.page_first'              
3 8 'Structure model' '_citation.page_last'               
4 8 'Structure model' '_citation_author.identifier_ORCID' 
5 8 'Structure model' '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9MIG 
_pdbx_database_status.recvd_initial_deposition_date   2024-12-12 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of Human NLRP3 complex with compound 3' 
_pdbx_database_related.db_id          EMD-48289 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              xiaodi.yu1981@gmail.com 
_pdbx_contact_author.name_first         Xiaodi 
_pdbx_contact_author.name_last          Yu 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-7520-0646 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Mammoliti, O.'    1  ? 
'Carbajo, R.J.'    2  ? 
'Perez-Benito, L.' 3  ? 
'Yu, X.'           4  ? 
'Prieri, M.L.C.'   5  ? 
'Bontempi, L.'     6  ? 
'Embrechts, S.'    7  ? 
'Paesmans, I.'     8  ? 
'Bassi, M.'        9  ? 
'Bhattacharya, A.' 10 ? 
'Roman, S.C.'      11 ? 
'Hoog, S.D.'       12 ? 
'Demin, S.'        13 ? 
'Gijsen, H.J.M.'   14 ? 
'Hache, G.'        15 ? 
'Jacobs, T.'       16 ? 
'Jerhaoui, S.'     17 ? 
'Leenaerts, J.'    18 ? 
'Lutter, F.H.'     19 ? 
'Matico, R.'       20 ? 
'Oehlrich, D.'     21 ? 
'Perrier, M.'      22 ? 
'Ryabchuk, P.'     23 ? 
'Schepens, W.'     24 ? 
'Sharma, S.'       25 ? 
'Somers, M.'       26 ? 
'Suarez, J.'       27 ? 
'Surkyn, M.'       28 ? 
'Opdenbosch, N.V.' 29 ? 
'Verhulst, T.'     30 ? 
'Bottelbergs, A.'  31 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            J.Med.Chem. 
_citation.journal_id_ASTM           JMCMAR 
_citation.journal_id_CSD            0151 
_citation.journal_id_ISSN           0022-2623 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            68 
_citation.language                  ? 
_citation.page_first                4848 
_citation.page_last                 4887 
_citation.title                     
'Discovery of Potent and Brain-Penetrant Bicyclic NLRP3 Inhibitors with Peripheral and Central In Vivo Activity.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1021/acs.jmedchem.4c03108 
_citation.pdbx_database_id_PubMed   39932543 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Mammoliti, O.'      1  ? 
primary 'Carbajo, R.'        2  ? 
primary 'Perez-Benito, L.'   3  ? 
primary 'Yu, X.'             4  ? 
primary 'Prieri, M.L.C.'     5  ? 
primary 'Bontempi, L.'       6  ? 
primary 'Embrechts, S.'      7  ? 
primary 'Paesmans, I.'       8  ? 
primary 'Bassi, M.'          9  ? 
primary 'Bhattacharya, A.'   10 ? 
primary 'Canellas, S.'       11 ? 
primary 'De Hoog, S.'        12 ? 
primary 'Demin, S.'          13 ? 
primary 'Gijsen, H.J.M.'     14 ? 
primary 'Hache, G.'          15 ? 
primary 'Jacobs, T.'         16 ? 
primary 'Jerhaoui, S.'       17 ? 
primary 'Leenaerts, J.'      18 ? 
primary 'Lutter, F.H.'       19 ? 
primary 'Mahieu, M.'         20 ? 
primary 'Matico, R.'         21 ? 
primary 'Miller, R.'         22 ? 
primary 'Oehlrich, D.'       23 ? 
primary 'Perrier, M.'        24 ? 
primary 'Ryabchuk, P.'       25 ? 
primary 'Schepens, W.'       26 ? 
primary 'Sharma, S.'         27 ? 
primary 'Somers, M.'         28 ? 
primary 'Suarez, J.'         29 ? 
primary 'Surkyn, M.'         30 ? 
primary 'Van Opdenbosch, N.' 31 ? 
primary 'Verhulst, T.'       32 ? 
primary 'Bottelbergs, A.'    33 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'NACHT, LRR and PYD domains-containing protein 3'                                                             
118323.531 1 3.6.4.- ? ? ? 
2 non-polymer syn "ADENOSINE-5'-TRIPHOSPHATE"                                                                                   
507.181    1 ?       ? ? ? 
3 non-polymer syn '(2P)-2-(4-{[(3R)-1-methylpiperidin-3-yl]amino}-5,6,7,8-tetrahydrophthalazin-1-yl)-5-(trifluoromethyl)phenol' 
406.445    1 ?       ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        
;Angiotensin/vasopressin receptor AII/AVP-like,Caterpiller protein 1.1,CLR1.1,Cold-induced autoinflammatory syndrome 1 protein,Cryopyrin,PYRIN-containing APAF1-like protein 1
;
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMIDFNGEEKAWAMAVWIFAAINR
RDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGLLEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGE
SVSLNKRYTRLRLIKEHRSQQEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM
LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCT
DWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQ
ENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ
KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEKEGRTNVPGSRLKLPSRDVTV
LLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEE
DFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL
VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSSNQKL
VELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAK
NPQCNLQKLGLVNSGLTSVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWD
LSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALETLQEEKPELTVVFEPSW
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMIDFNGEEKAWAMAVWIFAAINR
RDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGLLEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGE
SVSLNKRYTRLRLIKEHRSQQEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM
LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCT
DWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQ
ENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ
KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEKEGRTNVPGSRLKLPSRDVTV
LLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEE
DFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL
VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSSNQKL
VELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAK
NPQCNLQKLGLVNSGLTSVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWD
LSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALETLQEEKPELTVVFEPSW
;
_entity_poly.pdbx_strand_id                 C 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 "ADENOSINE-5'-TRIPHOSPHATE"                                                                                   ATP   
3 '(2P)-2-(4-{[(3R)-1-methylpiperidin-3-yl]amino}-5,6,7,8-tetrahydrophthalazin-1-yl)-5-(trifluoromethyl)phenol' A1BLQ 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1    MET n 
1 2    LYS n 
1 3    MET n 
1 4    ALA n 
1 5    SER n 
1 6    THR n 
1 7    ARG n 
1 8    CYS n 
1 9    LYS n 
1 10   LEU n 
1 11   ALA n 
1 12   ARG n 
1 13   TYR n 
1 14   LEU n 
1 15   GLU n 
1 16   ASP n 
1 17   LEU n 
1 18   GLU n 
1 19   ASP n 
1 20   VAL n 
1 21   ASP n 
1 22   LEU n 
1 23   LYS n 
1 24   LYS n 
1 25   PHE n 
1 26   LYS n 
1 27   MET n 
1 28   HIS n 
1 29   LEU n 
1 30   GLU n 
1 31   ASP n 
1 32   TYR n 
1 33   PRO n 
1 34   PRO n 
1 35   GLN n 
1 36   LYS n 
1 37   GLY n 
1 38   CYS n 
1 39   ILE n 
1 40   PRO n 
1 41   LEU n 
1 42   PRO n 
1 43   ARG n 
1 44   GLY n 
1 45   GLN n 
1 46   THR n 
1 47   GLU n 
1 48   LYS n 
1 49   ALA n 
1 50   ASP n 
1 51   HIS n 
1 52   VAL n 
1 53   ASP n 
1 54   LEU n 
1 55   ALA n 
1 56   THR n 
1 57   LEU n 
1 58   MET n 
1 59   ILE n 
1 60   ASP n 
1 61   PHE n 
1 62   ASN n 
1 63   GLY n 
1 64   GLU n 
1 65   GLU n 
1 66   LYS n 
1 67   ALA n 
1 68   TRP n 
1 69   ALA n 
1 70   MET n 
1 71   ALA n 
1 72   VAL n 
1 73   TRP n 
1 74   ILE n 
1 75   PHE n 
1 76   ALA n 
1 77   ALA n 
1 78   ILE n 
1 79   ASN n 
1 80   ARG n 
1 81   ARG n 
1 82   ASP n 
1 83   LEU n 
1 84   TYR n 
1 85   GLU n 
1 86   LYS n 
1 87   ALA n 
1 88   LYS n 
1 89   ARG n 
1 90   ASP n 
1 91   GLU n 
1 92   PRO n 
1 93   LYS n 
1 94   TRP n 
1 95   GLY n 
1 96   SER n 
1 97   ASP n 
1 98   ASN n 
1 99   ALA n 
1 100  ARG n 
1 101  VAL n 
1 102  SER n 
1 103  ASN n 
1 104  PRO n 
1 105  THR n 
1 106  VAL n 
1 107  ILE n 
1 108  CYS n 
1 109  GLN n 
1 110  GLU n 
1 111  ASP n 
1 112  SER n 
1 113  ILE n 
1 114  GLU n 
1 115  GLU n 
1 116  GLU n 
1 117  TRP n 
1 118  MET n 
1 119  GLY n 
1 120  LEU n 
1 121  LEU n 
1 122  GLU n 
1 123  TYR n 
1 124  LEU n 
1 125  SER n 
1 126  ARG n 
1 127  ILE n 
1 128  SER n 
1 129  ILE n 
1 130  CYS n 
1 131  LYS n 
1 132  MET n 
1 133  LYS n 
1 134  LYS n 
1 135  ASP n 
1 136  TYR n 
1 137  ARG n 
1 138  LYS n 
1 139  LYS n 
1 140  TYR n 
1 141  ARG n 
1 142  LYS n 
1 143  TYR n 
1 144  VAL n 
1 145  ARG n 
1 146  SER n 
1 147  ARG n 
1 148  PHE n 
1 149  GLN n 
1 150  CYS n 
1 151  ILE n 
1 152  GLU n 
1 153  ASP n 
1 154  ARG n 
1 155  ASN n 
1 156  ALA n 
1 157  ARG n 
1 158  LEU n 
1 159  GLY n 
1 160  GLU n 
1 161  SER n 
1 162  VAL n 
1 163  SER n 
1 164  LEU n 
1 165  ASN n 
1 166  LYS n 
1 167  ARG n 
1 168  TYR n 
1 169  THR n 
1 170  ARG n 
1 171  LEU n 
1 172  ARG n 
1 173  LEU n 
1 174  ILE n 
1 175  LYS n 
1 176  GLU n 
1 177  HIS n 
1 178  ARG n 
1 179  SER n 
1 180  GLN n 
1 181  GLN n 
1 182  GLU n 
1 183  ARG n 
1 184  GLU n 
1 185  GLN n 
1 186  GLU n 
1 187  LEU n 
1 188  LEU n 
1 189  ALA n 
1 190  ILE n 
1 191  GLY n 
1 192  LYS n 
1 193  THR n 
1 194  LYS n 
1 195  THR n 
1 196  CYS n 
1 197  GLU n 
1 198  SER n 
1 199  PRO n 
1 200  VAL n 
1 201  SER n 
1 202  PRO n 
1 203  ILE n 
1 204  LYS n 
1 205  MET n 
1 206  GLU n 
1 207  LEU n 
1 208  LEU n 
1 209  PHE n 
1 210  ASP n 
1 211  PRO n 
1 212  ASP n 
1 213  ASP n 
1 214  GLU n 
1 215  HIS n 
1 216  SER n 
1 217  GLU n 
1 218  PRO n 
1 219  VAL n 
1 220  HIS n 
1 221  THR n 
1 222  VAL n 
1 223  VAL n 
1 224  PHE n 
1 225  GLN n 
1 226  GLY n 
1 227  ALA n 
1 228  ALA n 
1 229  GLY n 
1 230  ILE n 
1 231  GLY n 
1 232  LYS n 
1 233  THR n 
1 234  ILE n 
1 235  LEU n 
1 236  ALA n 
1 237  ARG n 
1 238  LYS n 
1 239  MET n 
1 240  MET n 
1 241  LEU n 
1 242  ASP n 
1 243  TRP n 
1 244  ALA n 
1 245  SER n 
1 246  GLY n 
1 247  THR n 
1 248  LEU n 
1 249  TYR n 
1 250  GLN n 
1 251  ASP n 
1 252  ARG n 
1 253  PHE n 
1 254  ASP n 
1 255  TYR n 
1 256  LEU n 
1 257  PHE n 
1 258  TYR n 
1 259  ILE n 
1 260  HIS n 
1 261  CYS n 
1 262  ARG n 
1 263  GLU n 
1 264  VAL n 
1 265  SER n 
1 266  LEU n 
1 267  VAL n 
1 268  THR n 
1 269  GLN n 
1 270  ARG n 
1 271  SER n 
1 272  LEU n 
1 273  GLY n 
1 274  ASP n 
1 275  LEU n 
1 276  ILE n 
1 277  MET n 
1 278  SER n 
1 279  CYS n 
1 280  CYS n 
1 281  PRO n 
1 282  ASP n 
1 283  PRO n 
1 284  ASN n 
1 285  PRO n 
1 286  PRO n 
1 287  ILE n 
1 288  HIS n 
1 289  LYS n 
1 290  ILE n 
1 291  VAL n 
1 292  ARG n 
1 293  LYS n 
1 294  PRO n 
1 295  SER n 
1 296  ARG n 
1 297  ILE n 
1 298  LEU n 
1 299  PHE n 
1 300  LEU n 
1 301  MET n 
1 302  ASP n 
1 303  GLY n 
1 304  PHE n 
1 305  ASP n 
1 306  GLU n 
1 307  LEU n 
1 308  GLN n 
1 309  GLY n 
1 310  ALA n 
1 311  PHE n 
1 312  ASP n 
1 313  GLU n 
1 314  HIS n 
1 315  ILE n 
1 316  GLY n 
1 317  PRO n 
1 318  LEU n 
1 319  CYS n 
1 320  THR n 
1 321  ASP n 
1 322  TRP n 
1 323  GLN n 
1 324  LYS n 
1 325  ALA n 
1 326  GLU n 
1 327  ARG n 
1 328  GLY n 
1 329  ASP n 
1 330  ILE n 
1 331  LEU n 
1 332  LEU n 
1 333  SER n 
1 334  SER n 
1 335  LEU n 
1 336  ILE n 
1 337  ARG n 
1 338  LYS n 
1 339  LYS n 
1 340  LEU n 
1 341  LEU n 
1 342  PRO n 
1 343  GLU n 
1 344  ALA n 
1 345  SER n 
1 346  LEU n 
1 347  LEU n 
1 348  ILE n 
1 349  THR n 
1 350  THR n 
1 351  ARG n 
1 352  PRO n 
1 353  VAL n 
1 354  ALA n 
1 355  LEU n 
1 356  GLU n 
1 357  LYS n 
1 358  LEU n 
1 359  GLN n 
1 360  HIS n 
1 361  LEU n 
1 362  LEU n 
1 363  ASP n 
1 364  HIS n 
1 365  PRO n 
1 366  ARG n 
1 367  HIS n 
1 368  VAL n 
1 369  GLU n 
1 370  ILE n 
1 371  LEU n 
1 372  GLY n 
1 373  PHE n 
1 374  SER n 
1 375  GLU n 
1 376  ALA n 
1 377  LYS n 
1 378  ARG n 
1 379  LYS n 
1 380  GLU n 
1 381  TYR n 
1 382  PHE n 
1 383  PHE n 
1 384  LYS n 
1 385  TYR n 
1 386  PHE n 
1 387  SER n 
1 388  ASP n 
1 389  GLU n 
1 390  ALA n 
1 391  GLN n 
1 392  ALA n 
1 393  ARG n 
1 394  ALA n 
1 395  ALA n 
1 396  PHE n 
1 397  SER n 
1 398  LEU n 
1 399  ILE n 
1 400  GLN n 
1 401  GLU n 
1 402  ASN n 
1 403  GLU n 
1 404  VAL n 
1 405  LEU n 
1 406  PHE n 
1 407  THR n 
1 408  MET n 
1 409  CYS n 
1 410  PHE n 
1 411  ILE n 
1 412  PRO n 
1 413  LEU n 
1 414  VAL n 
1 415  CYS n 
1 416  TRP n 
1 417  ILE n 
1 418  VAL n 
1 419  CYS n 
1 420  THR n 
1 421  GLY n 
1 422  LEU n 
1 423  LYS n 
1 424  GLN n 
1 425  GLN n 
1 426  MET n 
1 427  GLU n 
1 428  SER n 
1 429  GLY n 
1 430  LYS n 
1 431  SER n 
1 432  LEU n 
1 433  ALA n 
1 434  GLN n 
1 435  THR n 
1 436  SER n 
1 437  LYS n 
1 438  THR n 
1 439  THR n 
1 440  THR n 
1 441  ALA n 
1 442  VAL n 
1 443  TYR n 
1 444  VAL n 
1 445  PHE n 
1 446  PHE n 
1 447  LEU n 
1 448  SER n 
1 449  SER n 
1 450  LEU n 
1 451  LEU n 
1 452  GLN n 
1 453  PRO n 
1 454  ARG n 
1 455  GLY n 
1 456  GLY n 
1 457  SER n 
1 458  GLN n 
1 459  GLU n 
1 460  HIS n 
1 461  GLY n 
1 462  LEU n 
1 463  CYS n 
1 464  ALA n 
1 465  HIS n 
1 466  LEU n 
1 467  TRP n 
1 468  GLY n 
1 469  LEU n 
1 470  CYS n 
1 471  SER n 
1 472  LEU n 
1 473  ALA n 
1 474  ALA n 
1 475  ASP n 
1 476  GLY n 
1 477  ILE n 
1 478  TRP n 
1 479  ASN n 
1 480  GLN n 
1 481  LYS n 
1 482  ILE n 
1 483  LEU n 
1 484  PHE n 
1 485  GLU n 
1 486  GLU n 
1 487  SER n 
1 488  ASP n 
1 489  LEU n 
1 490  ARG n 
1 491  ASN n 
1 492  HIS n 
1 493  GLY n 
1 494  LEU n 
1 495  GLN n 
1 496  LYS n 
1 497  ALA n 
1 498  ASP n 
1 499  VAL n 
1 500  SER n 
1 501  ALA n 
1 502  PHE n 
1 503  LEU n 
1 504  ARG n 
1 505  MET n 
1 506  ASN n 
1 507  LEU n 
1 508  PHE n 
1 509  GLN n 
1 510  LYS n 
1 511  GLU n 
1 512  VAL n 
1 513  ASP n 
1 514  CYS n 
1 515  GLU n 
1 516  LYS n 
1 517  PHE n 
1 518  TYR n 
1 519  SER n 
1 520  PHE n 
1 521  ILE n 
1 522  HIS n 
1 523  MET n 
1 524  THR n 
1 525  PHE n 
1 526  GLN n 
1 527  GLU n 
1 528  PHE n 
1 529  PHE n 
1 530  ALA n 
1 531  ALA n 
1 532  MET n 
1 533  TYR n 
1 534  TYR n 
1 535  LEU n 
1 536  LEU n 
1 537  GLU n 
1 538  GLU n 
1 539  GLU n 
1 540  LYS n 
1 541  GLU n 
1 542  GLY n 
1 543  ARG n 
1 544  THR n 
1 545  ASN n 
1 546  VAL n 
1 547  PRO n 
1 548  GLY n 
1 549  SER n 
1 550  ARG n 
1 551  LEU n 
1 552  LYS n 
1 553  LEU n 
1 554  PRO n 
1 555  SER n 
1 556  ARG n 
1 557  ASP n 
1 558  VAL n 
1 559  THR n 
1 560  VAL n 
1 561  LEU n 
1 562  LEU n 
1 563  GLU n 
1 564  ASN n 
1 565  TYR n 
1 566  GLY n 
1 567  LYS n 
1 568  PHE n 
1 569  GLU n 
1 570  LYS n 
1 571  GLY n 
1 572  TYR n 
1 573  LEU n 
1 574  ILE n 
1 575  PHE n 
1 576  VAL n 
1 577  VAL n 
1 578  ARG n 
1 579  PHE n 
1 580  LEU n 
1 581  PHE n 
1 582  GLY n 
1 583  LEU n 
1 584  VAL n 
1 585  ASN n 
1 586  GLN n 
1 587  GLU n 
1 588  ARG n 
1 589  THR n 
1 590  SER n 
1 591  TYR n 
1 592  LEU n 
1 593  GLU n 
1 594  LYS n 
1 595  LYS n 
1 596  LEU n 
1 597  SER n 
1 598  CYS n 
1 599  LYS n 
1 600  ILE n 
1 601  SER n 
1 602  GLN n 
1 603  GLN n 
1 604  ILE n 
1 605  ARG n 
1 606  LEU n 
1 607  GLU n 
1 608  LEU n 
1 609  LEU n 
1 610  LYS n 
1 611  TRP n 
1 612  ILE n 
1 613  GLU n 
1 614  VAL n 
1 615  LYS n 
1 616  ALA n 
1 617  LYS n 
1 618  ALA n 
1 619  LYS n 
1 620  LYS n 
1 621  LEU n 
1 622  GLN n 
1 623  ILE n 
1 624  GLN n 
1 625  PRO n 
1 626  SER n 
1 627  GLN n 
1 628  LEU n 
1 629  GLU n 
1 630  LEU n 
1 631  PHE n 
1 632  TYR n 
1 633  CYS n 
1 634  LEU n 
1 635  TYR n 
1 636  GLU n 
1 637  MET n 
1 638  GLN n 
1 639  GLU n 
1 640  GLU n 
1 641  ASP n 
1 642  PHE n 
1 643  VAL n 
1 644  GLN n 
1 645  ARG n 
1 646  ALA n 
1 647  MET n 
1 648  ASP n 
1 649  TYR n 
1 650  PHE n 
1 651  PRO n 
1 652  LYS n 
1 653  ILE n 
1 654  GLU n 
1 655  ILE n 
1 656  ASN n 
1 657  LEU n 
1 658  SER n 
1 659  THR n 
1 660  ARG n 
1 661  MET n 
1 662  ASP n 
1 663  HIS n 
1 664  MET n 
1 665  VAL n 
1 666  SER n 
1 667  SER n 
1 668  PHE n 
1 669  CYS n 
1 670  ILE n 
1 671  GLU n 
1 672  ASN n 
1 673  CYS n 
1 674  HIS n 
1 675  ARG n 
1 676  VAL n 
1 677  GLU n 
1 678  SER n 
1 679  LEU n 
1 680  SER n 
1 681  LEU n 
1 682  GLY n 
1 683  PHE n 
1 684  LEU n 
1 685  HIS n 
1 686  ASN n 
1 687  MET n 
1 688  PRO n 
1 689  LYS n 
1 690  GLU n 
1 691  GLU n 
1 692  GLU n 
1 693  GLU n 
1 694  GLU n 
1 695  GLU n 
1 696  LYS n 
1 697  GLU n 
1 698  GLY n 
1 699  ARG n 
1 700  HIS n 
1 701  LEU n 
1 702  ASP n 
1 703  MET n 
1 704  VAL n 
1 705  GLN n 
1 706  CYS n 
1 707  VAL n 
1 708  LEU n 
1 709  PRO n 
1 710  SER n 
1 711  SER n 
1 712  SER n 
1 713  HIS n 
1 714  ALA n 
1 715  ALA n 
1 716  CYS n 
1 717  SER n 
1 718  HIS n 
1 719  GLY n 
1 720  LEU n 
1 721  VAL n 
1 722  ASN n 
1 723  SER n 
1 724  HIS n 
1 725  LEU n 
1 726  THR n 
1 727  SER n 
1 728  SER n 
1 729  PHE n 
1 730  CYS n 
1 731  ARG n 
1 732  GLY n 
1 733  LEU n 
1 734  PHE n 
1 735  SER n 
1 736  VAL n 
1 737  LEU n 
1 738  SER n 
1 739  THR n 
1 740  SER n 
1 741  GLN n 
1 742  SER n 
1 743  LEU n 
1 744  THR n 
1 745  GLU n 
1 746  LEU n 
1 747  ASP n 
1 748  LEU n 
1 749  SER n 
1 750  ASP n 
1 751  ASN n 
1 752  SER n 
1 753  LEU n 
1 754  GLY n 
1 755  ASP n 
1 756  PRO n 
1 757  GLY n 
1 758  MET n 
1 759  ARG n 
1 760  VAL n 
1 761  LEU n 
1 762  CYS n 
1 763  GLU n 
1 764  THR n 
1 765  LEU n 
1 766  GLN n 
1 767  HIS n 
1 768  PRO n 
1 769  GLY n 
1 770  CYS n 
1 771  ASN n 
1 772  ILE n 
1 773  ARG n 
1 774  ARG n 
1 775  LEU n 
1 776  TRP n 
1 777  LEU n 
1 778  GLY n 
1 779  ARG n 
1 780  CYS n 
1 781  GLY n 
1 782  LEU n 
1 783  SER n 
1 784  HIS n 
1 785  GLU n 
1 786  CYS n 
1 787  CYS n 
1 788  PHE n 
1 789  ASP n 
1 790  ILE n 
1 791  SER n 
1 792  LEU n 
1 793  VAL n 
1 794  LEU n 
1 795  SER n 
1 796  SER n 
1 797  ASN n 
1 798  GLN n 
1 799  LYS n 
1 800  LEU n 
1 801  VAL n 
1 802  GLU n 
1 803  LEU n 
1 804  ASP n 
1 805  LEU n 
1 806  SER n 
1 807  ASP n 
1 808  ASN n 
1 809  ALA n 
1 810  LEU n 
1 811  GLY n 
1 812  ASP n 
1 813  PHE n 
1 814  GLY n 
1 815  ILE n 
1 816  ARG n 
1 817  LEU n 
1 818  LEU n 
1 819  CYS n 
1 820  VAL n 
1 821  GLY n 
1 822  LEU n 
1 823  LYS n 
1 824  HIS n 
1 825  LEU n 
1 826  LEU n 
1 827  CYS n 
1 828  ASN n 
1 829  LEU n 
1 830  LYS n 
1 831  LYS n 
1 832  LEU n 
1 833  TRP n 
1 834  LEU n 
1 835  VAL n 
1 836  SER n 
1 837  CYS n 
1 838  CYS n 
1 839  LEU n 
1 840  THR n 
1 841  SER n 
1 842  ALA n 
1 843  CYS n 
1 844  CYS n 
1 845  GLN n 
1 846  ASP n 
1 847  LEU n 
1 848  ALA n 
1 849  SER n 
1 850  VAL n 
1 851  LEU n 
1 852  SER n 
1 853  THR n 
1 854  SER n 
1 855  HIS n 
1 856  SER n 
1 857  LEU n 
1 858  THR n 
1 859  ARG n 
1 860  LEU n 
1 861  TYR n 
1 862  VAL n 
1 863  GLY n 
1 864  GLU n 
1 865  ASN n 
1 866  ALA n 
1 867  LEU n 
1 868  GLY n 
1 869  ASP n 
1 870  SER n 
1 871  GLY n 
1 872  VAL n 
1 873  ALA n 
1 874  ILE n 
1 875  LEU n 
1 876  CYS n 
1 877  GLU n 
1 878  LYS n 
1 879  ALA n 
1 880  LYS n 
1 881  ASN n 
1 882  PRO n 
1 883  GLN n 
1 884  CYS n 
1 885  ASN n 
1 886  LEU n 
1 887  GLN n 
1 888  LYS n 
1 889  LEU n 
1 890  GLY n 
1 891  LEU n 
1 892  VAL n 
1 893  ASN n 
1 894  SER n 
1 895  GLY n 
1 896  LEU n 
1 897  THR n 
1 898  SER n 
1 899  VAL n 
1 900  CYS n 
1 901  CYS n 
1 902  SER n 
1 903  ALA n 
1 904  LEU n 
1 905  SER n 
1 906  SER n 
1 907  VAL n 
1 908  LEU n 
1 909  SER n 
1 910  THR n 
1 911  ASN n 
1 912  GLN n 
1 913  ASN n 
1 914  LEU n 
1 915  THR n 
1 916  HIS n 
1 917  LEU n 
1 918  TYR n 
1 919  LEU n 
1 920  ARG n 
1 921  GLY n 
1 922  ASN n 
1 923  THR n 
1 924  LEU n 
1 925  GLY n 
1 926  ASP n 
1 927  LYS n 
1 928  GLY n 
1 929  ILE n 
1 930  LYS n 
1 931  LEU n 
1 932  LEU n 
1 933  CYS n 
1 934  GLU n 
1 935  GLY n 
1 936  LEU n 
1 937  LEU n 
1 938  HIS n 
1 939  PRO n 
1 940  ASP n 
1 941  CYS n 
1 942  LYS n 
1 943  LEU n 
1 944  GLN n 
1 945  VAL n 
1 946  LEU n 
1 947  GLU n 
1 948  LEU n 
1 949  ASP n 
1 950  ASN n 
1 951  CYS n 
1 952  ASN n 
1 953  LEU n 
1 954  THR n 
1 955  SER n 
1 956  HIS n 
1 957  CYS n 
1 958  CYS n 
1 959  TRP n 
1 960  ASP n 
1 961  LEU n 
1 962  SER n 
1 963  THR n 
1 964  LEU n 
1 965  LEU n 
1 966  THR n 
1 967  SER n 
1 968  SER n 
1 969  GLN n 
1 970  SER n 
1 971  LEU n 
1 972  ARG n 
1 973  LYS n 
1 974  LEU n 
1 975  SER n 
1 976  LEU n 
1 977  GLY n 
1 978  ASN n 
1 979  ASN n 
1 980  ASP n 
1 981  LEU n 
1 982  GLY n 
1 983  ASP n 
1 984  LEU n 
1 985  GLY n 
1 986  VAL n 
1 987  MET n 
1 988  MET n 
1 989  PHE n 
1 990  CYS n 
1 991  GLU n 
1 992  VAL n 
1 993  LEU n 
1 994  LYS n 
1 995  GLN n 
1 996  GLN n 
1 997  SER n 
1 998  CYS n 
1 999  LEU n 
1 1000 LEU n 
1 1001 GLN n 
1 1002 ASN n 
1 1003 LEU n 
1 1004 GLY n 
1 1005 LEU n 
1 1006 SER n 
1 1007 GLU n 
1 1008 MET n 
1 1009 TYR n 
1 1010 PHE n 
1 1011 ASN n 
1 1012 TYR n 
1 1013 GLU n 
1 1014 THR n 
1 1015 LYS n 
1 1016 SER n 
1 1017 ALA n 
1 1018 LEU n 
1 1019 GLU n 
1 1020 THR n 
1 1021 LEU n 
1 1022 GLN n 
1 1023 GLU n 
1 1024 GLU n 
1 1025 LYS n 
1 1026 PRO n 
1 1027 GLU n 
1 1028 LEU n 
1 1029 THR n 
1 1030 VAL n 
1 1031 VAL n 
1 1032 PHE n 
1 1033 GLU n 
1 1034 PRO n 
1 1035 SER n 
1 1036 TRP n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   1036 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'NLRP3, C1orf7, CIAS1, NALP3, PYPAF1' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Spodoptera frugiperda' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     7108 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1BLQ non-polymer         . 
'(2P)-2-(4-{[(3R)-1-methylpiperidin-3-yl]amino}-5,6,7,8-tetrahydrophthalazin-1-yl)-5-(trifluoromethyl)phenol' ? 'C21 H25 F3 N4 O' 
406.445 
ALA   'L-peptide linking' y ALANINE ? 'C3 H7 N O2'        89.093  
ARG   'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1'    175.209 
ASN   'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3'       132.118 
ASP   'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'        133.103 
ATP   non-polymer         . "ADENOSINE-5'-TRIPHOSPHATE" ? 'C10 H16 N5 O13 P3' 507.181 
CYS   'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S'      121.158 
GLN   'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3'      146.144 
GLU   'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'        147.129 
GLY   'peptide linking'   y GLYCINE ? 'C2 H5 N O2'        75.067  
HIS   'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1'    156.162 
ILE   'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2'       131.173 
LEU   'L-peptide linking' y LEUCINE ? 'C6 H13 N O2'       131.173 
LYS   'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1'    147.195 
MET   'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S'     149.211 
PHE   'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2'       165.189 
PRO   'L-peptide linking' y PROLINE ? 'C5 H9 N O2'        115.130 
SER   'L-peptide linking' y SERINE ? 'C3 H7 N O3'        105.093 
THR   'L-peptide linking' y THREONINE ? 'C4 H9 N O3'        119.119 
TRP   'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2'     204.225 
TYR   'L-peptide linking' y TYROSINE ? 'C9 H11 N O3'       181.189 
VAL   'L-peptide linking' y VALINE ? 'C5 H11 N O2'       117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1    MET 1    1    ?    ?   ?   C . n 
A 1 2    LYS 2    2    ?    ?   ?   C . n 
A 1 3    MET 3    3    ?    ?   ?   C . n 
A 1 4    ALA 4    4    ?    ?   ?   C . n 
A 1 5    SER 5    5    ?    ?   ?   C . n 
A 1 6    THR 6    6    ?    ?   ?   C . n 
A 1 7    ARG 7    7    ?    ?   ?   C . n 
A 1 8    CYS 8    8    ?    ?   ?   C . n 
A 1 9    LYS 9    9    ?    ?   ?   C . n 
A 1 10   LEU 10   10   ?    ?   ?   C . n 
A 1 11   ALA 11   11   ?    ?   ?   C . n 
A 1 12   ARG 12   12   ?    ?   ?   C . n 
A 1 13   TYR 13   13   ?    ?   ?   C . n 
A 1 14   LEU 14   14   ?    ?   ?   C . n 
A 1 15   GLU 15   15   ?    ?   ?   C . n 
A 1 16   ASP 16   16   ?    ?   ?   C . n 
A 1 17   LEU 17   17   ?    ?   ?   C . n 
A 1 18   GLU 18   18   ?    ?   ?   C . n 
A 1 19   ASP 19   19   ?    ?   ?   C . n 
A 1 20   VAL 20   20   ?    ?   ?   C . n 
A 1 21   ASP 21   21   ?    ?   ?   C . n 
A 1 22   LEU 22   22   ?    ?   ?   C . n 
A 1 23   LYS 23   23   ?    ?   ?   C . n 
A 1 24   LYS 24   24   ?    ?   ?   C . n 
A 1 25   PHE 25   25   ?    ?   ?   C . n 
A 1 26   LYS 26   26   ?    ?   ?   C . n 
A 1 27   MET 27   27   ?    ?   ?   C . n 
A 1 28   HIS 28   28   ?    ?   ?   C . n 
A 1 29   LEU 29   29   ?    ?   ?   C . n 
A 1 30   GLU 30   30   ?    ?   ?   C . n 
A 1 31   ASP 31   31   ?    ?   ?   C . n 
A 1 32   TYR 32   32   ?    ?   ?   C . n 
A 1 33   PRO 33   33   ?    ?   ?   C . n 
A 1 34   PRO 34   34   ?    ?   ?   C . n 
A 1 35   GLN 35   35   ?    ?   ?   C . n 
A 1 36   LYS 36   36   ?    ?   ?   C . n 
A 1 37   GLY 37   37   ?    ?   ?   C . n 
A 1 38   CYS 38   38   ?    ?   ?   C . n 
A 1 39   ILE 39   39   ?    ?   ?   C . n 
A 1 40   PRO 40   40   ?    ?   ?   C . n 
A 1 41   LEU 41   41   ?    ?   ?   C . n 
A 1 42   PRO 42   42   ?    ?   ?   C . n 
A 1 43   ARG 43   43   ?    ?   ?   C . n 
A 1 44   GLY 44   44   ?    ?   ?   C . n 
A 1 45   GLN 45   45   ?    ?   ?   C . n 
A 1 46   THR 46   46   ?    ?   ?   C . n 
A 1 47   GLU 47   47   ?    ?   ?   C . n 
A 1 48   LYS 48   48   ?    ?   ?   C . n 
A 1 49   ALA 49   49   ?    ?   ?   C . n 
A 1 50   ASP 50   50   ?    ?   ?   C . n 
A 1 51   HIS 51   51   ?    ?   ?   C . n 
A 1 52   VAL 52   52   ?    ?   ?   C . n 
A 1 53   ASP 53   53   ?    ?   ?   C . n 
A 1 54   LEU 54   54   ?    ?   ?   C . n 
A 1 55   ALA 55   55   ?    ?   ?   C . n 
A 1 56   THR 56   56   ?    ?   ?   C . n 
A 1 57   LEU 57   57   ?    ?   ?   C . n 
A 1 58   MET 58   58   ?    ?   ?   C . n 
A 1 59   ILE 59   59   ?    ?   ?   C . n 
A 1 60   ASP 60   60   ?    ?   ?   C . n 
A 1 61   PHE 61   61   ?    ?   ?   C . n 
A 1 62   ASN 62   62   ?    ?   ?   C . n 
A 1 63   GLY 63   63   ?    ?   ?   C . n 
A 1 64   GLU 64   64   ?    ?   ?   C . n 
A 1 65   GLU 65   65   ?    ?   ?   C . n 
A 1 66   LYS 66   66   ?    ?   ?   C . n 
A 1 67   ALA 67   67   ?    ?   ?   C . n 
A 1 68   TRP 68   68   ?    ?   ?   C . n 
A 1 69   ALA 69   69   ?    ?   ?   C . n 
A 1 70   MET 70   70   ?    ?   ?   C . n 
A 1 71   ALA 71   71   ?    ?   ?   C . n 
A 1 72   VAL 72   72   ?    ?   ?   C . n 
A 1 73   TRP 73   73   ?    ?   ?   C . n 
A 1 74   ILE 74   74   ?    ?   ?   C . n 
A 1 75   PHE 75   75   ?    ?   ?   C . n 
A 1 76   ALA 76   76   ?    ?   ?   C . n 
A 1 77   ALA 77   77   ?    ?   ?   C . n 
A 1 78   ILE 78   78   ?    ?   ?   C . n 
A 1 79   ASN 79   79   ?    ?   ?   C . n 
A 1 80   ARG 80   80   ?    ?   ?   C . n 
A 1 81   ARG 81   81   ?    ?   ?   C . n 
A 1 82   ASP 82   82   ?    ?   ?   C . n 
A 1 83   LEU 83   83   ?    ?   ?   C . n 
A 1 84   TYR 84   84   ?    ?   ?   C . n 
A 1 85   GLU 85   85   ?    ?   ?   C . n 
A 1 86   LYS 86   86   ?    ?   ?   C . n 
A 1 87   ALA 87   87   ?    ?   ?   C . n 
A 1 88   LYS 88   88   ?    ?   ?   C . n 
A 1 89   ARG 89   89   ?    ?   ?   C . n 
A 1 90   ASP 90   90   ?    ?   ?   C . n 
A 1 91   GLU 91   91   ?    ?   ?   C . n 
A 1 92   PRO 92   92   ?    ?   ?   C . n 
A 1 93   LYS 93   93   ?    ?   ?   C . n 
A 1 94   TRP 94   94   ?    ?   ?   C . n 
A 1 95   GLY 95   95   ?    ?   ?   C . n 
A 1 96   SER 96   96   ?    ?   ?   C . n 
A 1 97   ASP 97   97   ?    ?   ?   C . n 
A 1 98   ASN 98   98   ?    ?   ?   C . n 
A 1 99   ALA 99   99   ?    ?   ?   C . n 
A 1 100  ARG 100  100  ?    ?   ?   C . n 
A 1 101  VAL 101  101  ?    ?   ?   C . n 
A 1 102  SER 102  102  ?    ?   ?   C . n 
A 1 103  ASN 103  103  ?    ?   ?   C . n 
A 1 104  PRO 104  104  ?    ?   ?   C . n 
A 1 105  THR 105  105  ?    ?   ?   C . n 
A 1 106  VAL 106  106  ?    ?   ?   C . n 
A 1 107  ILE 107  107  ?    ?   ?   C . n 
A 1 108  CYS 108  108  ?    ?   ?   C . n 
A 1 109  GLN 109  109  ?    ?   ?   C . n 
A 1 110  GLU 110  110  ?    ?   ?   C . n 
A 1 111  ASP 111  111  ?    ?   ?   C . n 
A 1 112  SER 112  112  ?    ?   ?   C . n 
A 1 113  ILE 113  113  ?    ?   ?   C . n 
A 1 114  GLU 114  114  ?    ?   ?   C . n 
A 1 115  GLU 115  115  ?    ?   ?   C . n 
A 1 116  GLU 116  116  ?    ?   ?   C . n 
A 1 117  TRP 117  117  ?    ?   ?   C . n 
A 1 118  MET 118  118  ?    ?   ?   C . n 
A 1 119  GLY 119  119  ?    ?   ?   C . n 
A 1 120  LEU 120  120  ?    ?   ?   C . n 
A 1 121  LEU 121  121  ?    ?   ?   C . n 
A 1 122  GLU 122  122  ?    ?   ?   C . n 
A 1 123  TYR 123  123  ?    ?   ?   C . n 
A 1 124  LEU 124  124  ?    ?   ?   C . n 
A 1 125  SER 125  125  ?    ?   ?   C . n 
A 1 126  ARG 126  126  ?    ?   ?   C . n 
A 1 127  ILE 127  127  ?    ?   ?   C . n 
A 1 128  SER 128  128  ?    ?   ?   C . n 
A 1 129  ILE 129  129  ?    ?   ?   C . n 
A 1 130  CYS 130  130  ?    ?   ?   C . n 
A 1 131  LYS 131  131  ?    ?   ?   C . n 
A 1 132  MET 132  132  ?    ?   ?   C . n 
A 1 133  LYS 133  133  133  LYS LYS C . n 
A 1 134  LYS 134  134  134  LYS LYS C . n 
A 1 135  ASP 135  135  135  ASP ASP C . n 
A 1 136  TYR 136  136  136  TYR TYR C . n 
A 1 137  ARG 137  137  137  ARG ARG C . n 
A 1 138  LYS 138  138  138  LYS LYS C . n 
A 1 139  LYS 139  139  139  LYS LYS C . n 
A 1 140  TYR 140  140  140  TYR TYR C . n 
A 1 141  ARG 141  141  141  ARG ARG C . n 
A 1 142  LYS 142  142  142  LYS LYS C . n 
A 1 143  TYR 143  143  143  TYR TYR C . n 
A 1 144  VAL 144  144  144  VAL VAL C . n 
A 1 145  ARG 145  145  145  ARG ARG C . n 
A 1 146  SER 146  146  146  SER SER C . n 
A 1 147  ARG 147  147  147  ARG ARG C . n 
A 1 148  PHE 148  148  148  PHE PHE C . n 
A 1 149  GLN 149  149  149  GLN GLN C . n 
A 1 150  CYS 150  150  150  CYS CYS C . n 
A 1 151  ILE 151  151  151  ILE ILE C . n 
A 1 152  GLU 152  152  152  GLU GLU C . n 
A 1 153  ASP 153  153  153  ASP ASP C . n 
A 1 154  ARG 154  154  154  ARG ARG C . n 
A 1 155  ASN 155  155  155  ASN ASN C . n 
A 1 156  ALA 156  156  156  ALA ALA C . n 
A 1 157  ARG 157  157  157  ARG ARG C . n 
A 1 158  LEU 158  158  158  LEU LEU C . n 
A 1 159  GLY 159  159  159  GLY GLY C . n 
A 1 160  GLU 160  160  160  GLU GLU C . n 
A 1 161  SER 161  161  161  SER SER C . n 
A 1 162  VAL 162  162  162  VAL VAL C . n 
A 1 163  SER 163  163  163  SER SER C . n 
A 1 164  LEU 164  164  164  LEU LEU C . n 
A 1 165  ASN 165  165  165  ASN ASN C . n 
A 1 166  LYS 166  166  166  LYS LYS C . n 
A 1 167  ARG 167  167  167  ARG ARG C . n 
A 1 168  TYR 168  168  168  TYR TYR C . n 
A 1 169  THR 169  169  169  THR THR C . n 
A 1 170  ARG 170  170  170  ARG ARG C . n 
A 1 171  LEU 171  171  171  LEU LEU C . n 
A 1 172  ARG 172  172  172  ARG ARG C . n 
A 1 173  LEU 173  173  173  LEU LEU C . n 
A 1 174  ILE 174  174  174  ILE ILE C . n 
A 1 175  LYS 175  175  175  LYS LYS C . n 
A 1 176  GLU 176  176  176  GLU GLU C . n 
A 1 177  HIS 177  177  ?    ?   ?   C . n 
A 1 178  ARG 178  178  ?    ?   ?   C . n 
A 1 179  SER 179  179  ?    ?   ?   C . n 
A 1 180  GLN 180  180  ?    ?   ?   C . n 
A 1 181  GLN 181  181  ?    ?   ?   C . n 
A 1 182  GLU 182  182  ?    ?   ?   C . n 
A 1 183  ARG 183  183  ?    ?   ?   C . n 
A 1 184  GLU 184  184  ?    ?   ?   C . n 
A 1 185  GLN 185  185  ?    ?   ?   C . n 
A 1 186  GLU 186  186  ?    ?   ?   C . n 
A 1 187  LEU 187  187  ?    ?   ?   C . n 
A 1 188  LEU 188  188  ?    ?   ?   C . n 
A 1 189  ALA 189  189  ?    ?   ?   C . n 
A 1 190  ILE 190  190  ?    ?   ?   C . n 
A 1 191  GLY 191  191  ?    ?   ?   C . n 
A 1 192  LYS 192  192  ?    ?   ?   C . n 
A 1 193  THR 193  193  ?    ?   ?   C . n 
A 1 194  LYS 194  194  ?    ?   ?   C . n 
A 1 195  THR 195  195  ?    ?   ?   C . n 
A 1 196  CYS 196  196  ?    ?   ?   C . n 
A 1 197  GLU 197  197  ?    ?   ?   C . n 
A 1 198  SER 198  198  ?    ?   ?   C . n 
A 1 199  PRO 199  199  ?    ?   ?   C . n 
A 1 200  VAL 200  200  ?    ?   ?   C . n 
A 1 201  SER 201  201  201  SER SER C . n 
A 1 202  PRO 202  202  202  PRO PRO C . n 
A 1 203  ILE 203  203  203  ILE ILE C . n 
A 1 204  LYS 204  204  204  LYS LYS C . n 
A 1 205  MET 205  205  205  MET MET C . n 
A 1 206  GLU 206  206  206  GLU GLU C . n 
A 1 207  LEU 207  207  207  LEU LEU C . n 
A 1 208  LEU 208  208  208  LEU LEU C . n 
A 1 209  PHE 209  209  209  PHE PHE C . n 
A 1 210  ASP 210  210  210  ASP ASP C . n 
A 1 211  PRO 211  211  211  PRO PRO C . n 
A 1 212  ASP 212  212  212  ASP ASP C . n 
A 1 213  ASP 213  213  213  ASP ASP C . n 
A 1 214  GLU 214  214  214  GLU GLU C . n 
A 1 215  HIS 215  215  215  HIS HIS C . n 
A 1 216  SER 216  216  216  SER SER C . n 
A 1 217  GLU 217  217  217  GLU GLU C . n 
A 1 218  PRO 218  218  218  PRO PRO C . n 
A 1 219  VAL 219  219  219  VAL VAL C . n 
A 1 220  HIS 220  220  220  HIS HIS C . n 
A 1 221  THR 221  221  221  THR THR C . n 
A 1 222  VAL 222  222  222  VAL VAL C . n 
A 1 223  VAL 223  223  223  VAL VAL C . n 
A 1 224  PHE 224  224  224  PHE PHE C . n 
A 1 225  GLN 225  225  225  GLN GLN C . n 
A 1 226  GLY 226  226  226  GLY GLY C . n 
A 1 227  ALA 227  227  227  ALA ALA C . n 
A 1 228  ALA 228  228  228  ALA ALA C . n 
A 1 229  GLY 229  229  229  GLY GLY C . n 
A 1 230  ILE 230  230  230  ILE ILE C . n 
A 1 231  GLY 231  231  231  GLY GLY C . n 
A 1 232  LYS 232  232  232  LYS LYS C . n 
A 1 233  THR 233  233  233  THR THR C . n 
A 1 234  ILE 234  234  234  ILE ILE C . n 
A 1 235  LEU 235  235  235  LEU LEU C . n 
A 1 236  ALA 236  236  236  ALA ALA C . n 
A 1 237  ARG 237  237  237  ARG ARG C . n 
A 1 238  LYS 238  238  238  LYS LYS C . n 
A 1 239  MET 239  239  239  MET MET C . n 
A 1 240  MET 240  240  240  MET MET C . n 
A 1 241  LEU 241  241  241  LEU LEU C . n 
A 1 242  ASP 242  242  242  ASP ASP C . n 
A 1 243  TRP 243  243  243  TRP TRP C . n 
A 1 244  ALA 244  244  244  ALA ALA C . n 
A 1 245  SER 245  245  245  SER SER C . n 
A 1 246  GLY 246  246  246  GLY GLY C . n 
A 1 247  THR 247  247  247  THR THR C . n 
A 1 248  LEU 248  248  248  LEU LEU C . n 
A 1 249  TYR 249  249  249  TYR TYR C . n 
A 1 250  GLN 250  250  250  GLN GLN C . n 
A 1 251  ASP 251  251  251  ASP ASP C . n 
A 1 252  ARG 252  252  252  ARG ARG C . n 
A 1 253  PHE 253  253  253  PHE PHE C . n 
A 1 254  ASP 254  254  254  ASP ASP C . n 
A 1 255  TYR 255  255  255  TYR TYR C . n 
A 1 256  LEU 256  256  256  LEU LEU C . n 
A 1 257  PHE 257  257  257  PHE PHE C . n 
A 1 258  TYR 258  258  258  TYR TYR C . n 
A 1 259  ILE 259  259  259  ILE ILE C . n 
A 1 260  HIS 260  260  260  HIS HIS C . n 
A 1 261  CYS 261  261  261  CYS CYS C . n 
A 1 262  ARG 262  262  262  ARG ARG C . n 
A 1 263  GLU 263  263  263  GLU GLU C . n 
A 1 264  VAL 264  264  264  VAL VAL C . n 
A 1 265  SER 265  265  265  SER SER C . n 
A 1 266  LEU 266  266  266  LEU LEU C . n 
A 1 267  VAL 267  267  267  VAL VAL C . n 
A 1 268  THR 268  268  268  THR THR C . n 
A 1 269  GLN 269  269  269  GLN GLN C . n 
A 1 270  ARG 270  270  270  ARG ARG C . n 
A 1 271  SER 271  271  271  SER SER C . n 
A 1 272  LEU 272  272  272  LEU LEU C . n 
A 1 273  GLY 273  273  273  GLY GLY C . n 
A 1 274  ASP 274  274  274  ASP ASP C . n 
A 1 275  LEU 275  275  275  LEU LEU C . n 
A 1 276  ILE 276  276  276  ILE ILE C . n 
A 1 277  MET 277  277  277  MET MET C . n 
A 1 278  SER 278  278  278  SER SER C . n 
A 1 279  CYS 279  279  279  CYS CYS C . n 
A 1 280  CYS 280  280  280  CYS CYS C . n 
A 1 281  PRO 281  281  281  PRO PRO C . n 
A 1 282  ASP 282  282  282  ASP ASP C . n 
A 1 283  PRO 283  283  283  PRO PRO C . n 
A 1 284  ASN 284  284  284  ASN ASN C . n 
A 1 285  PRO 285  285  285  PRO PRO C . n 
A 1 286  PRO 286  286  286  PRO PRO C . n 
A 1 287  ILE 287  287  287  ILE ILE C . n 
A 1 288  HIS 288  288  288  HIS HIS C . n 
A 1 289  LYS 289  289  289  LYS LYS C . n 
A 1 290  ILE 290  290  290  ILE ILE C . n 
A 1 291  VAL 291  291  291  VAL VAL C . n 
A 1 292  ARG 292  292  292  ARG ARG C . n 
A 1 293  LYS 293  293  293  LYS LYS C . n 
A 1 294  PRO 294  294  294  PRO PRO C . n 
A 1 295  SER 295  295  295  SER SER C . n 
A 1 296  ARG 296  296  296  ARG ARG C . n 
A 1 297  ILE 297  297  297  ILE ILE C . n 
A 1 298  LEU 298  298  298  LEU LEU C . n 
A 1 299  PHE 299  299  299  PHE PHE C . n 
A 1 300  LEU 300  300  300  LEU LEU C . n 
A 1 301  MET 301  301  301  MET MET C . n 
A 1 302  ASP 302  302  302  ASP ASP C . n 
A 1 303  GLY 303  303  303  GLY GLY C . n 
A 1 304  PHE 304  304  304  PHE PHE C . n 
A 1 305  ASP 305  305  305  ASP ASP C . n 
A 1 306  GLU 306  306  306  GLU GLU C . n 
A 1 307  LEU 307  307  307  LEU LEU C . n 
A 1 308  GLN 308  308  308  GLN GLN C . n 
A 1 309  GLY 309  309  309  GLY GLY C . n 
A 1 310  ALA 310  310  310  ALA ALA C . n 
A 1 311  PHE 311  311  311  PHE PHE C . n 
A 1 312  ASP 312  312  312  ASP ASP C . n 
A 1 313  GLU 313  313  313  GLU GLU C . n 
A 1 314  HIS 314  314  314  HIS HIS C . n 
A 1 315  ILE 315  315  315  ILE ILE C . n 
A 1 316  GLY 316  316  316  GLY GLY C . n 
A 1 317  PRO 317  317  317  PRO PRO C . n 
A 1 318  LEU 318  318  318  LEU LEU C . n 
A 1 319  CYS 319  319  319  CYS CYS C . n 
A 1 320  THR 320  320  320  THR THR C . n 
A 1 321  ASP 321  321  321  ASP ASP C . n 
A 1 322  TRP 322  322  322  TRP TRP C . n 
A 1 323  GLN 323  323  323  GLN GLN C . n 
A 1 324  LYS 324  324  324  LYS LYS C . n 
A 1 325  ALA 325  325  325  ALA ALA C . n 
A 1 326  GLU 326  326  326  GLU GLU C . n 
A 1 327  ARG 327  327  327  ARG ARG C . n 
A 1 328  GLY 328  328  328  GLY GLY C . n 
A 1 329  ASP 329  329  329  ASP ASP C . n 
A 1 330  ILE 330  330  330  ILE ILE C . n 
A 1 331  LEU 331  331  331  LEU LEU C . n 
A 1 332  LEU 332  332  332  LEU LEU C . n 
A 1 333  SER 333  333  333  SER SER C . n 
A 1 334  SER 334  334  334  SER SER C . n 
A 1 335  LEU 335  335  335  LEU LEU C . n 
A 1 336  ILE 336  336  336  ILE ILE C . n 
A 1 337  ARG 337  337  337  ARG ARG C . n 
A 1 338  LYS 338  338  338  LYS LYS C . n 
A 1 339  LYS 339  339  339  LYS LYS C . n 
A 1 340  LEU 340  340  340  LEU LEU C . n 
A 1 341  LEU 341  341  341  LEU LEU C . n 
A 1 342  PRO 342  342  342  PRO PRO C . n 
A 1 343  GLU 343  343  343  GLU GLU C . n 
A 1 344  ALA 344  344  344  ALA ALA C . n 
A 1 345  SER 345  345  345  SER SER C . n 
A 1 346  LEU 346  346  346  LEU LEU C . n 
A 1 347  LEU 347  347  347  LEU LEU C . n 
A 1 348  ILE 348  348  348  ILE ILE C . n 
A 1 349  THR 349  349  349  THR THR C . n 
A 1 350  THR 350  350  350  THR THR C . n 
A 1 351  ARG 351  351  351  ARG ARG C . n 
A 1 352  PRO 352  352  352  PRO PRO C . n 
A 1 353  VAL 353  353  353  VAL VAL C . n 
A 1 354  ALA 354  354  354  ALA ALA C . n 
A 1 355  LEU 355  355  355  LEU LEU C . n 
A 1 356  GLU 356  356  356  GLU GLU C . n 
A 1 357  LYS 357  357  357  LYS LYS C . n 
A 1 358  LEU 358  358  358  LEU LEU C . n 
A 1 359  GLN 359  359  359  GLN GLN C . n 
A 1 360  HIS 360  360  360  HIS HIS C . n 
A 1 361  LEU 361  361  361  LEU LEU C . n 
A 1 362  LEU 362  362  362  LEU LEU C . n 
A 1 363  ASP 363  363  363  ASP ASP C . n 
A 1 364  HIS 364  364  364  HIS HIS C . n 
A 1 365  PRO 365  365  365  PRO PRO C . n 
A 1 366  ARG 366  366  366  ARG ARG C . n 
A 1 367  HIS 367  367  367  HIS HIS C . n 
A 1 368  VAL 368  368  368  VAL VAL C . n 
A 1 369  GLU 369  369  369  GLU GLU C . n 
A 1 370  ILE 370  370  370  ILE ILE C . n 
A 1 371  LEU 371  371  371  LEU LEU C . n 
A 1 372  GLY 372  372  372  GLY GLY C . n 
A 1 373  PHE 373  373  373  PHE PHE C . n 
A 1 374  SER 374  374  374  SER SER C . n 
A 1 375  GLU 375  375  375  GLU GLU C . n 
A 1 376  ALA 376  376  376  ALA ALA C . n 
A 1 377  LYS 377  377  377  LYS LYS C . n 
A 1 378  ARG 378  378  378  ARG ARG C . n 
A 1 379  LYS 379  379  379  LYS LYS C . n 
A 1 380  GLU 380  380  380  GLU GLU C . n 
A 1 381  TYR 381  381  381  TYR TYR C . n 
A 1 382  PHE 382  382  382  PHE PHE C . n 
A 1 383  PHE 383  383  383  PHE PHE C . n 
A 1 384  LYS 384  384  384  LYS LYS C . n 
A 1 385  TYR 385  385  385  TYR TYR C . n 
A 1 386  PHE 386  386  386  PHE PHE C . n 
A 1 387  SER 387  387  387  SER SER C . n 
A 1 388  ASP 388  388  388  ASP ASP C . n 
A 1 389  GLU 389  389  389  GLU GLU C . n 
A 1 390  ALA 390  390  390  ALA ALA C . n 
A 1 391  GLN 391  391  391  GLN GLN C . n 
A 1 392  ALA 392  392  392  ALA ALA C . n 
A 1 393  ARG 393  393  393  ARG ARG C . n 
A 1 394  ALA 394  394  394  ALA ALA C . n 
A 1 395  ALA 395  395  395  ALA ALA C . n 
A 1 396  PHE 396  396  396  PHE PHE C . n 
A 1 397  SER 397  397  397  SER SER C . n 
A 1 398  LEU 398  398  398  LEU LEU C . n 
A 1 399  ILE 399  399  399  ILE ILE C . n 
A 1 400  GLN 400  400  400  GLN GLN C . n 
A 1 401  GLU 401  401  401  GLU GLU C . n 
A 1 402  ASN 402  402  402  ASN ASN C . n 
A 1 403  GLU 403  403  403  GLU GLU C . n 
A 1 404  VAL 404  404  404  VAL VAL C . n 
A 1 405  LEU 405  405  405  LEU LEU C . n 
A 1 406  PHE 406  406  406  PHE PHE C . n 
A 1 407  THR 407  407  407  THR THR C . n 
A 1 408  MET 408  408  408  MET MET C . n 
A 1 409  CYS 409  409  409  CYS CYS C . n 
A 1 410  PHE 410  410  410  PHE PHE C . n 
A 1 411  ILE 411  411  411  ILE ILE C . n 
A 1 412  PRO 412  412  412  PRO PRO C . n 
A 1 413  LEU 413  413  413  LEU LEU C . n 
A 1 414  VAL 414  414  414  VAL VAL C . n 
A 1 415  CYS 415  415  415  CYS CYS C . n 
A 1 416  TRP 416  416  416  TRP TRP C . n 
A 1 417  ILE 417  417  417  ILE ILE C . n 
A 1 418  VAL 418  418  418  VAL VAL C . n 
A 1 419  CYS 419  419  419  CYS CYS C . n 
A 1 420  THR 420  420  420  THR THR C . n 
A 1 421  GLY 421  421  421  GLY GLY C . n 
A 1 422  LEU 422  422  422  LEU LEU C . n 
A 1 423  LYS 423  423  423  LYS LYS C . n 
A 1 424  GLN 424  424  424  GLN GLN C . n 
A 1 425  GLN 425  425  425  GLN GLN C . n 
A 1 426  MET 426  426  426  MET MET C . n 
A 1 427  GLU 427  427  427  GLU GLU C . n 
A 1 428  SER 428  428  428  SER SER C . n 
A 1 429  GLY 429  429  429  GLY GLY C . n 
A 1 430  LYS 430  430  430  LYS LYS C . n 
A 1 431  SER 431  431  431  SER SER C . n 
A 1 432  LEU 432  432  432  LEU LEU C . n 
A 1 433  ALA 433  433  433  ALA ALA C . n 
A 1 434  GLN 434  434  434  GLN GLN C . n 
A 1 435  THR 435  435  435  THR THR C . n 
A 1 436  SER 436  436  436  SER SER C . n 
A 1 437  LYS 437  437  437  LYS LYS C . n 
A 1 438  THR 438  438  438  THR THR C . n 
A 1 439  THR 439  439  439  THR THR C . n 
A 1 440  THR 440  440  440  THR THR C . n 
A 1 441  ALA 441  441  441  ALA ALA C . n 
A 1 442  VAL 442  442  442  VAL VAL C . n 
A 1 443  TYR 443  443  443  TYR TYR C . n 
A 1 444  VAL 444  444  444  VAL VAL C . n 
A 1 445  PHE 445  445  445  PHE PHE C . n 
A 1 446  PHE 446  446  446  PHE PHE C . n 
A 1 447  LEU 447  447  447  LEU LEU C . n 
A 1 448  SER 448  448  448  SER SER C . n 
A 1 449  SER 449  449  449  SER SER C . n 
A 1 450  LEU 450  450  450  LEU LEU C . n 
A 1 451  LEU 451  451  451  LEU LEU C . n 
A 1 452  GLN 452  452  452  GLN GLN C . n 
A 1 453  PRO 453  453  453  PRO PRO C . n 
A 1 454  ARG 454  454  ?    ?   ?   C . n 
A 1 455  GLY 455  455  ?    ?   ?   C . n 
A 1 456  GLY 456  456  ?    ?   ?   C . n 
A 1 457  SER 457  457  ?    ?   ?   C . n 
A 1 458  GLN 458  458  ?    ?   ?   C . n 
A 1 459  GLU 459  459  ?    ?   ?   C . n 
A 1 460  HIS 460  460  ?    ?   ?   C . n 
A 1 461  GLY 461  461  ?    ?   ?   C . n 
A 1 462  LEU 462  462  462  LEU LEU C . n 
A 1 463  CYS 463  463  463  CYS CYS C . n 
A 1 464  ALA 464  464  464  ALA ALA C . n 
A 1 465  HIS 465  465  465  HIS HIS C . n 
A 1 466  LEU 466  466  466  LEU LEU C . n 
A 1 467  TRP 467  467  467  TRP TRP C . n 
A 1 468  GLY 468  468  468  GLY GLY C . n 
A 1 469  LEU 469  469  469  LEU LEU C . n 
A 1 470  CYS 470  470  470  CYS CYS C . n 
A 1 471  SER 471  471  471  SER SER C . n 
A 1 472  LEU 472  472  472  LEU LEU C . n 
A 1 473  ALA 473  473  473  ALA ALA C . n 
A 1 474  ALA 474  474  474  ALA ALA C . n 
A 1 475  ASP 475  475  475  ASP ASP C . n 
A 1 476  GLY 476  476  476  GLY GLY C . n 
A 1 477  ILE 477  477  477  ILE ILE C . n 
A 1 478  TRP 478  478  478  TRP TRP C . n 
A 1 479  ASN 479  479  479  ASN ASN C . n 
A 1 480  GLN 480  480  480  GLN GLN C . n 
A 1 481  LYS 481  481  481  LYS LYS C . n 
A 1 482  ILE 482  482  482  ILE ILE C . n 
A 1 483  LEU 483  483  483  LEU LEU C . n 
A 1 484  PHE 484  484  484  PHE PHE C . n 
A 1 485  GLU 485  485  485  GLU GLU C . n 
A 1 486  GLU 486  486  486  GLU GLU C . n 
A 1 487  SER 487  487  487  SER SER C . n 
A 1 488  ASP 488  488  488  ASP ASP C . n 
A 1 489  LEU 489  489  489  LEU LEU C . n 
A 1 490  ARG 490  490  490  ARG ARG C . n 
A 1 491  ASN 491  491  491  ASN ASN C . n 
A 1 492  HIS 492  492  492  HIS HIS C . n 
A 1 493  GLY 493  493  493  GLY GLY C . n 
A 1 494  LEU 494  494  494  LEU LEU C . n 
A 1 495  GLN 495  495  495  GLN GLN C . n 
A 1 496  LYS 496  496  496  LYS LYS C . n 
A 1 497  ALA 497  497  497  ALA ALA C . n 
A 1 498  ASP 498  498  498  ASP ASP C . n 
A 1 499  VAL 499  499  499  VAL VAL C . n 
A 1 500  SER 500  500  500  SER SER C . n 
A 1 501  ALA 501  501  501  ALA ALA C . n 
A 1 502  PHE 502  502  502  PHE PHE C . n 
A 1 503  LEU 503  503  503  LEU LEU C . n 
A 1 504  ARG 504  504  504  ARG ARG C . n 
A 1 505  MET 505  505  505  MET MET C . n 
A 1 506  ASN 506  506  506  ASN ASN C . n 
A 1 507  LEU 507  507  507  LEU LEU C . n 
A 1 508  PHE 508  508  508  PHE PHE C . n 
A 1 509  GLN 509  509  509  GLN GLN C . n 
A 1 510  LYS 510  510  510  LYS LYS C . n 
A 1 511  GLU 511  511  511  GLU GLU C . n 
A 1 512  VAL 512  512  512  VAL VAL C . n 
A 1 513  ASP 513  513  513  ASP ASP C . n 
A 1 514  CYS 514  514  514  CYS CYS C . n 
A 1 515  GLU 515  515  515  GLU GLU C . n 
A 1 516  LYS 516  516  516  LYS LYS C . n 
A 1 517  PHE 517  517  517  PHE PHE C . n 
A 1 518  TYR 518  518  518  TYR TYR C . n 
A 1 519  SER 519  519  519  SER SER C . n 
A 1 520  PHE 520  520  520  PHE PHE C . n 
A 1 521  ILE 521  521  521  ILE ILE C . n 
A 1 522  HIS 522  522  522  HIS HIS C . n 
A 1 523  MET 523  523  523  MET MET C . n 
A 1 524  THR 524  524  524  THR THR C . n 
A 1 525  PHE 525  525  525  PHE PHE C . n 
A 1 526  GLN 526  526  526  GLN GLN C . n 
A 1 527  GLU 527  527  527  GLU GLU C . n 
A 1 528  PHE 528  528  528  PHE PHE C . n 
A 1 529  PHE 529  529  529  PHE PHE C . n 
A 1 530  ALA 530  530  530  ALA ALA C . n 
A 1 531  ALA 531  531  531  ALA ALA C . n 
A 1 532  MET 532  532  532  MET MET C . n 
A 1 533  TYR 533  533  533  TYR TYR C . n 
A 1 534  TYR 534  534  534  TYR TYR C . n 
A 1 535  LEU 535  535  535  LEU LEU C . n 
A 1 536  LEU 536  536  536  LEU LEU C . n 
A 1 537  GLU 537  537  537  GLU GLU C . n 
A 1 538  GLU 538  538  ?    ?   ?   C . n 
A 1 539  GLU 539  539  ?    ?   ?   C . n 
A 1 540  LYS 540  540  ?    ?   ?   C . n 
A 1 541  GLU 541  541  ?    ?   ?   C . n 
A 1 542  GLY 542  542  ?    ?   ?   C . n 
A 1 543  ARG 543  543  ?    ?   ?   C . n 
A 1 544  THR 544  544  ?    ?   ?   C . n 
A 1 545  ASN 545  545  ?    ?   ?   C . n 
A 1 546  VAL 546  546  ?    ?   ?   C . n 
A 1 547  PRO 547  547  ?    ?   ?   C . n 
A 1 548  GLY 548  548  ?    ?   ?   C . n 
A 1 549  SER 549  549  ?    ?   ?   C . n 
A 1 550  ARG 550  550  ?    ?   ?   C . n 
A 1 551  LEU 551  551  ?    ?   ?   C . n 
A 1 552  LYS 552  552  ?    ?   ?   C . n 
A 1 553  LEU 553  553  553  LEU LEU C . n 
A 1 554  PRO 554  554  554  PRO PRO C . n 
A 1 555  SER 555  555  555  SER SER C . n 
A 1 556  ARG 556  556  556  ARG ARG C . n 
A 1 557  ASP 557  557  557  ASP ASP C . n 
A 1 558  VAL 558  558  558  VAL VAL C . n 
A 1 559  THR 559  559  559  THR THR C . n 
A 1 560  VAL 560  560  560  VAL VAL C . n 
A 1 561  LEU 561  561  561  LEU LEU C . n 
A 1 562  LEU 562  562  562  LEU LEU C . n 
A 1 563  GLU 563  563  563  GLU GLU C . n 
A 1 564  ASN 564  564  564  ASN ASN C . n 
A 1 565  TYR 565  565  565  TYR TYR C . n 
A 1 566  GLY 566  566  566  GLY GLY C . n 
A 1 567  LYS 567  567  567  LYS LYS C . n 
A 1 568  PHE 568  568  568  PHE PHE C . n 
A 1 569  GLU 569  569  569  GLU GLU C . n 
A 1 570  LYS 570  570  570  LYS LYS C . n 
A 1 571  GLY 571  571  571  GLY GLY C . n 
A 1 572  TYR 572  572  572  TYR TYR C . n 
A 1 573  LEU 573  573  573  LEU LEU C . n 
A 1 574  ILE 574  574  574  ILE ILE C . n 
A 1 575  PHE 575  575  575  PHE PHE C . n 
A 1 576  VAL 576  576  576  VAL VAL C . n 
A 1 577  VAL 577  577  577  VAL VAL C . n 
A 1 578  ARG 578  578  578  ARG ARG C . n 
A 1 579  PHE 579  579  579  PHE PHE C . n 
A 1 580  LEU 580  580  580  LEU LEU C . n 
A 1 581  PHE 581  581  581  PHE PHE C . n 
A 1 582  GLY 582  582  582  GLY GLY C . n 
A 1 583  LEU 583  583  583  LEU LEU C . n 
A 1 584  VAL 584  584  584  VAL VAL C . n 
A 1 585  ASN 585  585  585  ASN ASN C . n 
A 1 586  GLN 586  586  586  GLN GLN C . n 
A 1 587  GLU 587  587  587  GLU GLU C . n 
A 1 588  ARG 588  588  588  ARG ARG C . n 
A 1 589  THR 589  589  589  THR THR C . n 
A 1 590  SER 590  590  590  SER SER C . n 
A 1 591  TYR 591  591  591  TYR TYR C . n 
A 1 592  LEU 592  592  592  LEU LEU C . n 
A 1 593  GLU 593  593  593  GLU GLU C . n 
A 1 594  LYS 594  594  594  LYS LYS C . n 
A 1 595  LYS 595  595  595  LYS LYS C . n 
A 1 596  LEU 596  596  596  LEU LEU C . n 
A 1 597  SER 597  597  597  SER SER C . n 
A 1 598  CYS 598  598  598  CYS CYS C . n 
A 1 599  LYS 599  599  599  LYS LYS C . n 
A 1 600  ILE 600  600  600  ILE ILE C . n 
A 1 601  SER 601  601  601  SER SER C . n 
A 1 602  GLN 602  602  602  GLN GLN C . n 
A 1 603  GLN 603  603  603  GLN GLN C . n 
A 1 604  ILE 604  604  604  ILE ILE C . n 
A 1 605  ARG 605  605  605  ARG ARG C . n 
A 1 606  LEU 606  606  606  LEU LEU C . n 
A 1 607  GLU 607  607  607  GLU GLU C . n 
A 1 608  LEU 608  608  608  LEU LEU C . n 
A 1 609  LEU 609  609  609  LEU LEU C . n 
A 1 610  LYS 610  610  610  LYS LYS C . n 
A 1 611  TRP 611  611  611  TRP TRP C . n 
A 1 612  ILE 612  612  612  ILE ILE C . n 
A 1 613  GLU 613  613  613  GLU GLU C . n 
A 1 614  VAL 614  614  614  VAL VAL C . n 
A 1 615  LYS 615  615  615  LYS LYS C . n 
A 1 616  ALA 616  616  616  ALA ALA C . n 
A 1 617  LYS 617  617  617  LYS LYS C . n 
A 1 618  ALA 618  618  618  ALA ALA C . n 
A 1 619  LYS 619  619  619  LYS LYS C . n 
A 1 620  LYS 620  620  620  LYS LYS C . n 
A 1 621  LEU 621  621  621  LEU LEU C . n 
A 1 622  GLN 622  622  622  GLN GLN C . n 
A 1 623  ILE 623  623  623  ILE ILE C . n 
A 1 624  GLN 624  624  624  GLN GLN C . n 
A 1 625  PRO 625  625  625  PRO PRO C . n 
A 1 626  SER 626  626  626  SER SER C . n 
A 1 627  GLN 627  627  627  GLN GLN C . n 
A 1 628  LEU 628  628  628  LEU LEU C . n 
A 1 629  GLU 629  629  629  GLU GLU C . n 
A 1 630  LEU 630  630  630  LEU LEU C . n 
A 1 631  PHE 631  631  631  PHE PHE C . n 
A 1 632  TYR 632  632  632  TYR TYR C . n 
A 1 633  CYS 633  633  633  CYS CYS C . n 
A 1 634  LEU 634  634  634  LEU LEU C . n 
A 1 635  TYR 635  635  635  TYR TYR C . n 
A 1 636  GLU 636  636  636  GLU GLU C . n 
A 1 637  MET 637  637  637  MET MET C . n 
A 1 638  GLN 638  638  638  GLN GLN C . n 
A 1 639  GLU 639  639  639  GLU GLU C . n 
A 1 640  GLU 640  640  640  GLU GLU C . n 
A 1 641  ASP 641  641  641  ASP ASP C . n 
A 1 642  PHE 642  642  642  PHE PHE C . n 
A 1 643  VAL 643  643  643  VAL VAL C . n 
A 1 644  GLN 644  644  644  GLN GLN C . n 
A 1 645  ARG 645  645  645  ARG ARG C . n 
A 1 646  ALA 646  646  646  ALA ALA C . n 
A 1 647  MET 647  647  647  MET MET C . n 
A 1 648  ASP 648  648  648  ASP ASP C . n 
A 1 649  TYR 649  649  649  TYR TYR C . n 
A 1 650  PHE 650  650  650  PHE PHE C . n 
A 1 651  PRO 651  651  651  PRO PRO C . n 
A 1 652  LYS 652  652  652  LYS LYS C . n 
A 1 653  ILE 653  653  653  ILE ILE C . n 
A 1 654  GLU 654  654  654  GLU GLU C . n 
A 1 655  ILE 655  655  655  ILE ILE C . n 
A 1 656  ASN 656  656  656  ASN ASN C . n 
A 1 657  LEU 657  657  657  LEU LEU C . n 
A 1 658  SER 658  658  658  SER SER C . n 
A 1 659  THR 659  659  659  THR THR C . n 
A 1 660  ARG 660  660  660  ARG ARG C . n 
A 1 661  MET 661  661  661  MET MET C . n 
A 1 662  ASP 662  662  662  ASP ASP C . n 
A 1 663  HIS 663  663  663  HIS HIS C . n 
A 1 664  MET 664  664  664  MET MET C . n 
A 1 665  VAL 665  665  665  VAL VAL C . n 
A 1 666  SER 666  666  666  SER SER C . n 
A 1 667  SER 667  667  667  SER SER C . n 
A 1 668  PHE 668  668  668  PHE PHE C . n 
A 1 669  CYS 669  669  669  CYS CYS C . n 
A 1 670  ILE 670  670  670  ILE ILE C . n 
A 1 671  GLU 671  671  671  GLU GLU C . n 
A 1 672  ASN 672  672  672  ASN ASN C . n 
A 1 673  CYS 673  673  673  CYS CYS C . n 
A 1 674  HIS 674  674  674  HIS HIS C . n 
A 1 675  ARG 675  675  675  ARG ARG C . n 
A 1 676  VAL 676  676  676  VAL VAL C . n 
A 1 677  GLU 677  677  677  GLU GLU C . n 
A 1 678  SER 678  678  678  SER SER C . n 
A 1 679  LEU 679  679  679  LEU LEU C . n 
A 1 680  SER 680  680  680  SER SER C . n 
A 1 681  LEU 681  681  681  LEU LEU C . n 
A 1 682  GLY 682  682  682  GLY GLY C . n 
A 1 683  PHE 683  683  683  PHE PHE C . n 
A 1 684  LEU 684  684  684  LEU LEU C . n 
A 1 685  HIS 685  685  685  HIS HIS C . n 
A 1 686  ASN 686  686  686  ASN ASN C . n 
A 1 687  MET 687  687  ?    ?   ?   C . n 
A 1 688  PRO 688  688  ?    ?   ?   C . n 
A 1 689  LYS 689  689  ?    ?   ?   C . n 
A 1 690  GLU 690  690  ?    ?   ?   C . n 
A 1 691  GLU 691  691  ?    ?   ?   C . n 
A 1 692  GLU 692  692  ?    ?   ?   C . n 
A 1 693  GLU 693  693  ?    ?   ?   C . n 
A 1 694  GLU 694  694  ?    ?   ?   C . n 
A 1 695  GLU 695  695  ?    ?   ?   C . n 
A 1 696  LYS 696  696  ?    ?   ?   C . n 
A 1 697  GLU 697  697  ?    ?   ?   C . n 
A 1 698  GLY 698  698  ?    ?   ?   C . n 
A 1 699  ARG 699  699  ?    ?   ?   C . n 
A 1 700  HIS 700  700  ?    ?   ?   C . n 
A 1 701  LEU 701  701  ?    ?   ?   C . n 
A 1 702  ASP 702  702  ?    ?   ?   C . n 
A 1 703  MET 703  703  ?    ?   ?   C . n 
A 1 704  VAL 704  704  ?    ?   ?   C . n 
A 1 705  GLN 705  705  ?    ?   ?   C . n 
A 1 706  CYS 706  706  ?    ?   ?   C . n 
A 1 707  VAL 707  707  ?    ?   ?   C . n 
A 1 708  LEU 708  708  ?    ?   ?   C . n 
A 1 709  PRO 709  709  ?    ?   ?   C . n 
A 1 710  SER 710  710  ?    ?   ?   C . n 
A 1 711  SER 711  711  ?    ?   ?   C . n 
A 1 712  SER 712  712  ?    ?   ?   C . n 
A 1 713  HIS 713  713  ?    ?   ?   C . n 
A 1 714  ALA 714  714  ?    ?   ?   C . n 
A 1 715  ALA 715  715  ?    ?   ?   C . n 
A 1 716  CYS 716  716  ?    ?   ?   C . n 
A 1 717  SER 717  717  ?    ?   ?   C . n 
A 1 718  HIS 718  718  ?    ?   ?   C . n 
A 1 719  GLY 719  719  ?    ?   ?   C . n 
A 1 720  LEU 720  720  ?    ?   ?   C . n 
A 1 721  VAL 721  721  ?    ?   ?   C . n 
A 1 722  ASN 722  722  ?    ?   ?   C . n 
A 1 723  SER 723  723  ?    ?   ?   C . n 
A 1 724  HIS 724  724  ?    ?   ?   C . n 
A 1 725  LEU 725  725  725  LEU LEU C . n 
A 1 726  THR 726  726  726  THR THR C . n 
A 1 727  SER 727  727  727  SER SER C . n 
A 1 728  SER 728  728  728  SER SER C . n 
A 1 729  PHE 729  729  729  PHE PHE C . n 
A 1 730  CYS 730  730  730  CYS CYS C . n 
A 1 731  ARG 731  731  731  ARG ARG C . n 
A 1 732  GLY 732  732  732  GLY GLY C . n 
A 1 733  LEU 733  733  733  LEU LEU C . n 
A 1 734  PHE 734  734  734  PHE PHE C . n 
A 1 735  SER 735  735  735  SER SER C . n 
A 1 736  VAL 736  736  736  VAL VAL C . n 
A 1 737  LEU 737  737  737  LEU LEU C . n 
A 1 738  SER 738  738  738  SER SER C . n 
A 1 739  THR 739  739  739  THR THR C . n 
A 1 740  SER 740  740  740  SER SER C . n 
A 1 741  GLN 741  741  741  GLN GLN C . n 
A 1 742  SER 742  742  742  SER SER C . n 
A 1 743  LEU 743  743  743  LEU LEU C . n 
A 1 744  THR 744  744  744  THR THR C . n 
A 1 745  GLU 745  745  745  GLU GLU C . n 
A 1 746  LEU 746  746  746  LEU LEU C . n 
A 1 747  ASP 747  747  747  ASP ASP C . n 
A 1 748  LEU 748  748  748  LEU LEU C . n 
A 1 749  SER 749  749  749  SER SER C . n 
A 1 750  ASP 750  750  750  ASP ASP C . n 
A 1 751  ASN 751  751  751  ASN ASN C . n 
A 1 752  SER 752  752  752  SER SER C . n 
A 1 753  LEU 753  753  753  LEU LEU C . n 
A 1 754  GLY 754  754  754  GLY GLY C . n 
A 1 755  ASP 755  755  755  ASP ASP C . n 
A 1 756  PRO 756  756  756  PRO PRO C . n 
A 1 757  GLY 757  757  757  GLY GLY C . n 
A 1 758  MET 758  758  758  MET MET C . n 
A 1 759  ARG 759  759  759  ARG ARG C . n 
A 1 760  VAL 760  760  760  VAL VAL C . n 
A 1 761  LEU 761  761  761  LEU LEU C . n 
A 1 762  CYS 762  762  762  CYS CYS C . n 
A 1 763  GLU 763  763  763  GLU GLU C . n 
A 1 764  THR 764  764  764  THR THR C . n 
A 1 765  LEU 765  765  765  LEU LEU C . n 
A 1 766  GLN 766  766  766  GLN GLN C . n 
A 1 767  HIS 767  767  767  HIS HIS C . n 
A 1 768  PRO 768  768  768  PRO PRO C . n 
A 1 769  GLY 769  769  769  GLY GLY C . n 
A 1 770  CYS 770  770  770  CYS CYS C . n 
A 1 771  ASN 771  771  771  ASN ASN C . n 
A 1 772  ILE 772  772  772  ILE ILE C . n 
A 1 773  ARG 773  773  773  ARG ARG C . n 
A 1 774  ARG 774  774  774  ARG ARG C . n 
A 1 775  LEU 775  775  775  LEU LEU C . n 
A 1 776  TRP 776  776  776  TRP TRP C . n 
A 1 777  LEU 777  777  777  LEU LEU C . n 
A 1 778  GLY 778  778  778  GLY GLY C . n 
A 1 779  ARG 779  779  779  ARG ARG C . n 
A 1 780  CYS 780  780  780  CYS CYS C . n 
A 1 781  GLY 781  781  781  GLY GLY C . n 
A 1 782  LEU 782  782  782  LEU LEU C . n 
A 1 783  SER 783  783  783  SER SER C . n 
A 1 784  HIS 784  784  784  HIS HIS C . n 
A 1 785  GLU 785  785  785  GLU GLU C . n 
A 1 786  CYS 786  786  786  CYS CYS C . n 
A 1 787  CYS 787  787  787  CYS CYS C . n 
A 1 788  PHE 788  788  788  PHE PHE C . n 
A 1 789  ASP 789  789  789  ASP ASP C . n 
A 1 790  ILE 790  790  790  ILE ILE C . n 
A 1 791  SER 791  791  791  SER SER C . n 
A 1 792  LEU 792  792  792  LEU LEU C . n 
A 1 793  VAL 793  793  793  VAL VAL C . n 
A 1 794  LEU 794  794  794  LEU LEU C . n 
A 1 795  SER 795  795  795  SER SER C . n 
A 1 796  SER 796  796  796  SER SER C . n 
A 1 797  ASN 797  797  797  ASN ASN C . n 
A 1 798  GLN 798  798  798  GLN GLN C . n 
A 1 799  LYS 799  799  799  LYS LYS C . n 
A 1 800  LEU 800  800  800  LEU LEU C . n 
A 1 801  VAL 801  801  801  VAL VAL C . n 
A 1 802  GLU 802  802  802  GLU GLU C . n 
A 1 803  LEU 803  803  803  LEU LEU C . n 
A 1 804  ASP 804  804  804  ASP ASP C . n 
A 1 805  LEU 805  805  805  LEU LEU C . n 
A 1 806  SER 806  806  806  SER SER C . n 
A 1 807  ASP 807  807  807  ASP ASP C . n 
A 1 808  ASN 808  808  808  ASN ASN C . n 
A 1 809  ALA 809  809  809  ALA ALA C . n 
A 1 810  LEU 810  810  810  LEU LEU C . n 
A 1 811  GLY 811  811  811  GLY GLY C . n 
A 1 812  ASP 812  812  812  ASP ASP C . n 
A 1 813  PHE 813  813  813  PHE PHE C . n 
A 1 814  GLY 814  814  814  GLY GLY C . n 
A 1 815  ILE 815  815  815  ILE ILE C . n 
A 1 816  ARG 816  816  816  ARG ARG C . n 
A 1 817  LEU 817  817  817  LEU LEU C . n 
A 1 818  LEU 818  818  818  LEU LEU C . n 
A 1 819  CYS 819  819  819  CYS CYS C . n 
A 1 820  VAL 820  820  820  VAL VAL C . n 
A 1 821  GLY 821  821  821  GLY GLY C . n 
A 1 822  LEU 822  822  822  LEU LEU C . n 
A 1 823  LYS 823  823  823  LYS LYS C . n 
A 1 824  HIS 824  824  824  HIS HIS C . n 
A 1 825  LEU 825  825  825  LEU LEU C . n 
A 1 826  LEU 826  826  826  LEU LEU C . n 
A 1 827  CYS 827  827  827  CYS CYS C . n 
A 1 828  ASN 828  828  828  ASN ASN C . n 
A 1 829  LEU 829  829  829  LEU LEU C . n 
A 1 830  LYS 830  830  830  LYS LYS C . n 
A 1 831  LYS 831  831  831  LYS LYS C . n 
A 1 832  LEU 832  832  832  LEU LEU C . n 
A 1 833  TRP 833  833  833  TRP TRP C . n 
A 1 834  LEU 834  834  834  LEU LEU C . n 
A 1 835  VAL 835  835  835  VAL VAL C . n 
A 1 836  SER 836  836  836  SER SER C . n 
A 1 837  CYS 837  837  837  CYS CYS C . n 
A 1 838  CYS 838  838  838  CYS CYS C . n 
A 1 839  LEU 839  839  839  LEU LEU C . n 
A 1 840  THR 840  840  840  THR THR C . n 
A 1 841  SER 841  841  841  SER SER C . n 
A 1 842  ALA 842  842  842  ALA ALA C . n 
A 1 843  CYS 843  843  843  CYS CYS C . n 
A 1 844  CYS 844  844  844  CYS CYS C . n 
A 1 845  GLN 845  845  845  GLN GLN C . n 
A 1 846  ASP 846  846  846  ASP ASP C . n 
A 1 847  LEU 847  847  847  LEU LEU C . n 
A 1 848  ALA 848  848  848  ALA ALA C . n 
A 1 849  SER 849  849  849  SER SER C . n 
A 1 850  VAL 850  850  850  VAL VAL C . n 
A 1 851  LEU 851  851  851  LEU LEU C . n 
A 1 852  SER 852  852  852  SER SER C . n 
A 1 853  THR 853  853  853  THR THR C . n 
A 1 854  SER 854  854  854  SER SER C . n 
A 1 855  HIS 855  855  855  HIS HIS C . n 
A 1 856  SER 856  856  856  SER SER C . n 
A 1 857  LEU 857  857  857  LEU LEU C . n 
A 1 858  THR 858  858  858  THR THR C . n 
A 1 859  ARG 859  859  859  ARG ARG C . n 
A 1 860  LEU 860  860  860  LEU LEU C . n 
A 1 861  TYR 861  861  861  TYR TYR C . n 
A 1 862  VAL 862  862  862  VAL VAL C . n 
A 1 863  GLY 863  863  863  GLY GLY C . n 
A 1 864  GLU 864  864  864  GLU GLU C . n 
A 1 865  ASN 865  865  865  ASN ASN C . n 
A 1 866  ALA 866  866  866  ALA ALA C . n 
A 1 867  LEU 867  867  867  LEU LEU C . n 
A 1 868  GLY 868  868  868  GLY GLY C . n 
A 1 869  ASP 869  869  869  ASP ASP C . n 
A 1 870  SER 870  870  870  SER SER C . n 
A 1 871  GLY 871  871  871  GLY GLY C . n 
A 1 872  VAL 872  872  872  VAL VAL C . n 
A 1 873  ALA 873  873  873  ALA ALA C . n 
A 1 874  ILE 874  874  874  ILE ILE C . n 
A 1 875  LEU 875  875  875  LEU LEU C . n 
A 1 876  CYS 876  876  876  CYS CYS C . n 
A 1 877  GLU 877  877  877  GLU GLU C . n 
A 1 878  LYS 878  878  878  LYS LYS C . n 
A 1 879  ALA 879  879  879  ALA ALA C . n 
A 1 880  LYS 880  880  880  LYS LYS C . n 
A 1 881  ASN 881  881  881  ASN ASN C . n 
A 1 882  PRO 882  882  882  PRO PRO C . n 
A 1 883  GLN 883  883  883  GLN GLN C . n 
A 1 884  CYS 884  884  884  CYS CYS C . n 
A 1 885  ASN 885  885  885  ASN ASN C . n 
A 1 886  LEU 886  886  886  LEU LEU C . n 
A 1 887  GLN 887  887  887  GLN GLN C . n 
A 1 888  LYS 888  888  888  LYS LYS C . n 
A 1 889  LEU 889  889  889  LEU LEU C . n 
A 1 890  GLY 890  890  890  GLY GLY C . n 
A 1 891  LEU 891  891  891  LEU LEU C . n 
A 1 892  VAL 892  892  892  VAL VAL C . n 
A 1 893  ASN 893  893  893  ASN ASN C . n 
A 1 894  SER 894  894  894  SER SER C . n 
A 1 895  GLY 895  895  895  GLY GLY C . n 
A 1 896  LEU 896  896  896  LEU LEU C . n 
A 1 897  THR 897  897  897  THR THR C . n 
A 1 898  SER 898  898  898  SER SER C . n 
A 1 899  VAL 899  899  899  VAL VAL C . n 
A 1 900  CYS 900  900  900  CYS CYS C . n 
A 1 901  CYS 901  901  901  CYS CYS C . n 
A 1 902  SER 902  902  902  SER SER C . n 
A 1 903  ALA 903  903  903  ALA ALA C . n 
A 1 904  LEU 904  904  904  LEU LEU C . n 
A 1 905  SER 905  905  905  SER SER C . n 
A 1 906  SER 906  906  906  SER SER C . n 
A 1 907  VAL 907  907  907  VAL VAL C . n 
A 1 908  LEU 908  908  908  LEU LEU C . n 
A 1 909  SER 909  909  909  SER SER C . n 
A 1 910  THR 910  910  910  THR THR C . n 
A 1 911  ASN 911  911  911  ASN ASN C . n 
A 1 912  GLN 912  912  912  GLN GLN C . n 
A 1 913  ASN 913  913  913  ASN ASN C . n 
A 1 914  LEU 914  914  914  LEU LEU C . n 
A 1 915  THR 915  915  915  THR THR C . n 
A 1 916  HIS 916  916  916  HIS HIS C . n 
A 1 917  LEU 917  917  917  LEU LEU C . n 
A 1 918  TYR 918  918  918  TYR TYR C . n 
A 1 919  LEU 919  919  919  LEU LEU C . n 
A 1 920  ARG 920  920  920  ARG ARG C . n 
A 1 921  GLY 921  921  921  GLY GLY C . n 
A 1 922  ASN 922  922  922  ASN ASN C . n 
A 1 923  THR 923  923  923  THR THR C . n 
A 1 924  LEU 924  924  924  LEU LEU C . n 
A 1 925  GLY 925  925  925  GLY GLY C . n 
A 1 926  ASP 926  926  926  ASP ASP C . n 
A 1 927  LYS 927  927  927  LYS LYS C . n 
A 1 928  GLY 928  928  928  GLY GLY C . n 
A 1 929  ILE 929  929  929  ILE ILE C . n 
A 1 930  LYS 930  930  930  LYS LYS C . n 
A 1 931  LEU 931  931  931  LEU LEU C . n 
A 1 932  LEU 932  932  932  LEU LEU C . n 
A 1 933  CYS 933  933  933  CYS CYS C . n 
A 1 934  GLU 934  934  934  GLU GLU C . n 
A 1 935  GLY 935  935  935  GLY GLY C . n 
A 1 936  LEU 936  936  936  LEU LEU C . n 
A 1 937  LEU 937  937  937  LEU LEU C . n 
A 1 938  HIS 938  938  938  HIS HIS C . n 
A 1 939  PRO 939  939  939  PRO PRO C . n 
A 1 940  ASP 940  940  940  ASP ASP C . n 
A 1 941  CYS 941  941  941  CYS CYS C . n 
A 1 942  LYS 942  942  942  LYS LYS C . n 
A 1 943  LEU 943  943  943  LEU LEU C . n 
A 1 944  GLN 944  944  944  GLN GLN C . n 
A 1 945  VAL 945  945  945  VAL VAL C . n 
A 1 946  LEU 946  946  946  LEU LEU C . n 
A 1 947  GLU 947  947  947  GLU GLU C . n 
A 1 948  LEU 948  948  948  LEU LEU C . n 
A 1 949  ASP 949  949  949  ASP ASP C . n 
A 1 950  ASN 950  950  950  ASN ASN C . n 
A 1 951  CYS 951  951  951  CYS CYS C . n 
A 1 952  ASN 952  952  952  ASN ASN C . n 
A 1 953  LEU 953  953  953  LEU LEU C . n 
A 1 954  THR 954  954  954  THR THR C . n 
A 1 955  SER 955  955  955  SER SER C . n 
A 1 956  HIS 956  956  956  HIS HIS C . n 
A 1 957  CYS 957  957  957  CYS CYS C . n 
A 1 958  CYS 958  958  958  CYS CYS C . n 
A 1 959  TRP 959  959  959  TRP TRP C . n 
A 1 960  ASP 960  960  960  ASP ASP C . n 
A 1 961  LEU 961  961  961  LEU LEU C . n 
A 1 962  SER 962  962  962  SER SER C . n 
A 1 963  THR 963  963  963  THR THR C . n 
A 1 964  LEU 964  964  964  LEU LEU C . n 
A 1 965  LEU 965  965  965  LEU LEU C . n 
A 1 966  THR 966  966  966  THR THR C . n 
A 1 967  SER 967  967  967  SER SER C . n 
A 1 968  SER 968  968  968  SER SER C . n 
A 1 969  GLN 969  969  969  GLN GLN C . n 
A 1 970  SER 970  970  970  SER SER C . n 
A 1 971  LEU 971  971  971  LEU LEU C . n 
A 1 972  ARG 972  972  972  ARG ARG C . n 
A 1 973  LYS 973  973  973  LYS LYS C . n 
A 1 974  LEU 974  974  974  LEU LEU C . n 
A 1 975  SER 975  975  975  SER SER C . n 
A 1 976  LEU 976  976  976  LEU LEU C . n 
A 1 977  GLY 977  977  977  GLY GLY C . n 
A 1 978  ASN 978  978  978  ASN ASN C . n 
A 1 979  ASN 979  979  979  ASN ASN C . n 
A 1 980  ASP 980  980  980  ASP ASP C . n 
A 1 981  LEU 981  981  981  LEU LEU C . n 
A 1 982  GLY 982  982  982  GLY GLY C . n 
A 1 983  ASP 983  983  983  ASP ASP C . n 
A 1 984  LEU 984  984  984  LEU LEU C . n 
A 1 985  GLY 985  985  985  GLY GLY C . n 
A 1 986  VAL 986  986  986  VAL VAL C . n 
A 1 987  MET 987  987  987  MET MET C . n 
A 1 988  MET 988  988  988  MET MET C . n 
A 1 989  PHE 989  989  989  PHE PHE C . n 
A 1 990  CYS 990  990  990  CYS CYS C . n 
A 1 991  GLU 991  991  991  GLU GLU C . n 
A 1 992  VAL 992  992  992  VAL VAL C . n 
A 1 993  LEU 993  993  993  LEU LEU C . n 
A 1 994  LYS 994  994  994  LYS LYS C . n 
A 1 995  GLN 995  995  995  GLN GLN C . n 
A 1 996  GLN 996  996  996  GLN GLN C . n 
A 1 997  SER 997  997  997  SER SER C . n 
A 1 998  CYS 998  998  998  CYS CYS C . n 
A 1 999  LEU 999  999  999  LEU LEU C . n 
A 1 1000 LEU 1000 1000 1000 LEU LEU C . n 
A 1 1001 GLN 1001 1001 1001 GLN GLN C . n 
A 1 1002 ASN 1002 1002 1002 ASN ASN C . n 
A 1 1003 LEU 1003 1003 1003 LEU LEU C . n 
A 1 1004 GLY 1004 1004 1004 GLY GLY C . n 
A 1 1005 LEU 1005 1005 1005 LEU LEU C . n 
A 1 1006 SER 1006 1006 1006 SER SER C . n 
A 1 1007 GLU 1007 1007 1007 GLU GLU C . n 
A 1 1008 MET 1008 1008 1008 MET MET C . n 
A 1 1009 TYR 1009 1009 1009 TYR TYR C . n 
A 1 1010 PHE 1010 1010 1010 PHE PHE C . n 
A 1 1011 ASN 1011 1011 1011 ASN ASN C . n 
A 1 1012 TYR 1012 1012 1012 TYR TYR C . n 
A 1 1013 GLU 1013 1013 1013 GLU GLU C . n 
A 1 1014 THR 1014 1014 1014 THR THR C . n 
A 1 1015 LYS 1015 1015 1015 LYS LYS C . n 
A 1 1016 SER 1016 1016 1016 SER SER C . n 
A 1 1017 ALA 1017 1017 1017 ALA ALA C . n 
A 1 1018 LEU 1018 1018 1018 LEU LEU C . n 
A 1 1019 GLU 1019 1019 1019 GLU GLU C . n 
A 1 1020 THR 1020 1020 1020 THR THR C . n 
A 1 1021 LEU 1021 1021 1021 LEU LEU C . n 
A 1 1022 GLN 1022 1022 1022 GLN GLN C . n 
A 1 1023 GLU 1023 1023 1023 GLU GLU C . n 
A 1 1024 GLU 1024 1024 1024 GLU GLU C . n 
A 1 1025 LYS 1025 1025 1025 LYS LYS C . n 
A 1 1026 PRO 1026 1026 1026 PRO PRO C . n 
A 1 1027 GLU 1027 1027 1027 GLU GLU C . n 
A 1 1028 LEU 1028 1028 1028 LEU LEU C . n 
A 1 1029 THR 1029 1029 1029 THR THR C . n 
A 1 1030 VAL 1030 1030 1030 VAL VAL C . n 
A 1 1031 VAL 1031 1031 1031 VAL VAL C . n 
A 1 1032 PHE 1032 1032 1032 PHE PHE C . n 
A 1 1033 GLU 1033 1033 1033 GLU GLU C . n 
A 1 1034 PRO 1034 1034 1034 PRO PRO C . n 
A 1 1035 SER 1035 1035 1035 SER SER C . n 
A 1 1036 TRP 1036 1036 ?    ?   ?   C . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        A1BLQ 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   A1BLQ 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 ATP   1 1201 1201 ATP   ATP C . 
C 3 A1BLQ 1 1202 1202 A1BLQ LIG C . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9MIG 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9MIG 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9MIG 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9MIG 
_struct.title                        'Cryo-EM structure of Human NLRP3 complex with compound 3' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9MIG 
_struct_keywords.text            'NLRP3, cryo-EM, small molecule inhibitor, inflammasome, IMMUNE SYSTEM' 
_struct_keywords.pdbx_keywords   'IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    NLRP3_HUMAN 
_struct_ref.pdbx_db_accession          Q96P20 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMIDFNGEEKAWAMAVWIFAAINR
RDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGLLEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGE
SVSLNKRYTRLRLIKEHRSQQEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMM
LDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCT
DWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQ
ENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQ
KILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEKEGRTNVPGSRLKLPSRDVTV
LLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEE
DFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGL
VNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSSNQKL
VELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAK
NPQCNLQKLGLVNSGLTSVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWD
LSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALETLQEEKPELTVVFEPSW
;
_struct_ref.pdbx_align_begin           1 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9MIG 
_struct_ref_seq.pdbx_strand_id                C 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 1036 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             Q96P20 
_struct_ref_seq.db_align_beg                  1 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  1036 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       1036 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 TYR A 136  ? PHE A 148  ? TYR C 136  PHE C 148  1 ? 13 
HELX_P HELX_P2  AA2 LEU A 164  ? TYR A 168  ? LEU C 164  TYR C 168  5 ? 5  
HELX_P HELX_P3  AA3 GLY A 231  ? SER A 245  ? GLY C 231  SER C 245  1 ? 15 
HELX_P HELX_P4  AA4 ARG A 262  ? VAL A 264  ? ARG C 262  VAL C 264  5 ? 3  
HELX_P HELX_P5  AA5 GLY A 273  ? SER A 278  ? GLY C 273  SER C 278  1 ? 6  
HELX_P HELX_P6  AA6 LYS A 289  ? LYS A 293  ? LYS C 289  LYS C 293  5 ? 5  
HELX_P HELX_P7  AA7 GLY A 303  ? LEU A 307  ? GLY C 303  LEU C 307  5 ? 5  
HELX_P HELX_P8  AA8 GLY A 328  ? ARG A 337  ? GLY C 328  ARG C 337  1 ? 10 
HELX_P HELX_P9  AA9 ARG A 351  ? LYS A 357  ? ARG C 351  LYS C 357  5 ? 7  
HELX_P HELX_P10 AB1 LEU A 358  ? ASP A 363  ? LEU C 358  ASP C 363  1 ? 6  
HELX_P HELX_P11 AB2 SER A 374  ? PHE A 386  ? SER C 374  PHE C 386  1 ? 13 
HELX_P HELX_P12 AB3 ASP A 388  ? GLU A 401  ? ASP C 388  GLU C 401  1 ? 14 
HELX_P HELX_P13 AB4 ASN A 402  ? CYS A 409  ? ASN C 402  CYS C 409  1 ? 8  
HELX_P HELX_P14 AB5 ILE A 411  ? SER A 428  ? ILE C 411  SER C 428  1 ? 18 
HELX_P HELX_P15 AB6 THR A 438  ? GLN A 452  ? THR C 438  GLN C 452  1 ? 15 
HELX_P HELX_P16 AB7 LEU A 462  ? ALA A 464  ? LEU C 462  ALA C 464  5 ? 3  
HELX_P HELX_P17 AB8 HIS A 465  ? ASN A 479  ? HIS C 465  ASN C 479  1 ? 15 
HELX_P HELX_P18 AB9 GLU A 485  ? ASN A 491  ? GLU C 485  ASN C 491  1 ? 7  
HELX_P HELX_P19 AC1 ALA A 497  ? MET A 505  ? ALA C 497  MET C 505  1 ? 9  
HELX_P HELX_P20 AC2 HIS A 522  ? TYR A 534  ? HIS C 522  TYR C 534  1 ? 13 
HELX_P HELX_P21 AC3 ASP A 557  ? ASN A 564  ? ASP C 557  ASN C 564  1 ? 8  
HELX_P HELX_P22 AC4 LYS A 567  ? GLY A 571  ? LYS C 567  GLY C 571  5 ? 5  
HELX_P HELX_P23 AC5 LEU A 573  ? VAL A 584  ? LEU C 573  VAL C 584  1 ? 12 
HELX_P HELX_P24 AC6 LEU A 592  ? LEU A 596  ? LEU C 592  LEU C 596  5 ? 5  
HELX_P HELX_P25 AC7 SER A 597  ? ALA A 618  ? SER C 597  ALA C 618  1 ? 22 
HELX_P HELX_P26 AC8 LEU A 628  ? MET A 637  ? LEU C 628  MET C 637  1 ? 10 
HELX_P HELX_P27 AC9 GLU A 639  ? MET A 647  ? GLU C 639  MET C 647  1 ? 9  
HELX_P HELX_P28 AD1 ASP A 648  ? PHE A 650  ? ASP C 648  PHE C 650  5 ? 3  
HELX_P HELX_P29 AD2 THR A 659  ? ASN A 672  ? THR C 659  ASN C 672  1 ? 14 
HELX_P HELX_P30 AD3 CYS A 730  ? SER A 738  ? CYS C 730  SER C 738  1 ? 9  
HELX_P HELX_P31 AD4 GLY A 754  ? LEU A 765  ? GLY C 754  LEU C 765  1 ? 12 
HELX_P HELX_P32 AD5 GLU A 785  ? SER A 795  ? GLU C 785  SER C 795  1 ? 11 
HELX_P HELX_P33 AD6 GLY A 811  ? LYS A 823  ? GLY C 811  LYS C 823  1 ? 13 
HELX_P HELX_P34 AD7 THR A 840  ? ALA A 842  ? THR C 840  ALA C 842  5 ? 3  
HELX_P HELX_P35 AD8 CYS A 843  ? SER A 854  ? CYS C 843  SER C 854  1 ? 12 
HELX_P HELX_P36 AD9 GLY A 868  ? LYS A 880  ? GLY C 868  LYS C 880  1 ? 13 
HELX_P HELX_P37 AE1 THR A 897  ? VAL A 899  ? THR C 897  VAL C 899  5 ? 3  
HELX_P HELX_P38 AE2 CYS A 900  ? ASN A 911  ? CYS C 900  ASN C 911  1 ? 12 
HELX_P HELX_P39 AE3 LEU A 924  ? LEU A 937  ? LEU C 924  LEU C 937  1 ? 14 
HELX_P HELX_P40 AE4 THR A 954  ? HIS A 956  ? THR C 954  HIS C 956  5 ? 3  
HELX_P HELX_P41 AE5 CYS A 957  ? SER A 968  ? CYS C 957  SER C 968  1 ? 12 
HELX_P HELX_P42 AE6 GLY A 982  ? LEU A 993  ? GLY C 982  LEU C 993  1 ? 12 
HELX_P HELX_P43 AE7 ASN A 1011 ? LYS A 1025 ? ASN C 1011 LYS C 1025 1 ? 15 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 7  ? 
AA2 ? 2  ? 
AA3 ? 2  ? 
AA4 ? 11 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1  2  ? anti-parallel 
AA1 2  3  ? anti-parallel 
AA1 3  4  ? parallel      
AA1 4  5  ? parallel      
AA1 5  6  ? parallel      
AA1 6  7  ? parallel      
AA2 1  2  ? anti-parallel 
AA3 1  2  ? anti-parallel 
AA4 1  2  ? parallel      
AA4 2  3  ? parallel      
AA4 3  4  ? parallel      
AA4 4  5  ? parallel      
AA4 5  6  ? parallel      
AA4 6  7  ? parallel      
AA4 7  8  ? parallel      
AA4 8  9  ? parallel      
AA4 9  10 ? parallel      
AA4 10 11 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1  PRO A 202 ? ILE A 203 ? PRO C 202 ILE C 203 
AA1 2  LEU A 173 ? LYS A 175 ? LEU C 173 LYS C 175 
AA1 3  ARG A 366 ? ILE A 370 ? ARG C 366 ILE C 370 
AA1 4  THR A 221 ? GLN A 225 ? THR C 221 GLN C 225 
AA1 5  SER A 345 ? THR A 350 ? SER C 345 THR C 350 
AA1 6  ILE A 297 ? ASP A 302 ? ILE C 297 ASP C 302 
AA1 7  TYR A 255 ? HIS A 260 ? TYR C 255 HIS C 260 
AA2 1  GLN A 269 ? ARG A 270 ? GLN C 269 ARG C 270 
AA2 2  GLU A 326 ? ARG A 327 ? GLU C 326 ARG C 327 
AA3 1  PHE A 508 ? GLN A 509 ? PHE C 508 GLN C 509 
AA3 2  SER A 519 ? PHE A 520 ? SER C 519 PHE C 520 
AA4 1  LYS A 652 ? LEU A 657 ? LYS C 652 LEU C 657 
AA4 2  SER A 678 ? PHE A 683 ? SER C 678 PHE C 683 
AA4 3  GLU A 745 ? ASP A 747 ? GLU C 745 ASP C 747 
AA4 4  ARG A 774 ? TRP A 776 ? ARG C 774 TRP C 776 
AA4 5  GLU A 802 ? ASP A 804 ? GLU C 802 ASP C 804 
AA4 6  LYS A 831 ? TRP A 833 ? LYS C 831 TRP C 833 
AA4 7  ARG A 859 ? TYR A 861 ? ARG C 859 TYR C 861 
AA4 8  LYS A 888 ? LEU A 889 ? LYS C 888 LEU C 889 
AA4 9  HIS A 916 ? TYR A 918 ? HIS C 916 TYR C 918 
AA4 10 VAL A 945 ? LEU A 948 ? VAL C 945 LEU C 948 
AA4 11 LYS A 973 ? LEU A 976 ? LYS C 973 LEU C 976 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1  2  O ILE A 203 ? O ILE C 203 N LEU A 173 ? N LEU C 173 
AA1 2  3  N ILE A 174 ? N ILE C 174 O GLU A 369 ? O GLU C 369 
AA1 3  4  O ARG A 366 ? O ARG C 366 N VAL A 223 ? N VAL C 223 
AA1 4  5  N PHE A 224 ? N PHE C 224 O ILE A 348 ? O ILE C 348 
AA1 5  6  O LEU A 347 ? O LEU C 347 N MET A 301 ? N MET C 301 
AA1 6  7  O LEU A 300 ? O LEU C 300 N ILE A 259 ? N ILE C 259 
AA2 1  2  N ARG A 270 ? N ARG C 270 O GLU A 326 ? O GLU C 326 
AA3 1  2  N GLN A 509 ? N GLN C 509 O SER A 519 ? O SER C 519 
AA4 1  2  N ILE A 655 ? N ILE C 655 O GLY A 682 ? O GLY C 682 
AA4 2  3  N LEU A 679 ? N LEU C 679 O ASP A 747 ? O ASP C 747 
AA4 3  4  N LEU A 746 ? N LEU C 746 O ARG A 774 ? O ARG C 774 
AA4 4  5  N LEU A 775 ? N LEU C 775 O GLU A 802 ? O GLU C 802 
AA4 5  6  N LEU A 803 ? N LEU C 803 O LYS A 831 ? O LYS C 831 
AA4 6  7  N LEU A 832 ? N LEU C 832 O ARG A 859 ? O ARG C 859 
AA4 7  8  N LEU A 860 ? N LEU C 860 O LYS A 888 ? O LYS C 888 
AA4 8  9  N LEU A 889 ? N LEU C 889 O HIS A 916 ? O HIS C 916 
AA4 9  10 N LEU A 917 ? N LEU C 917 O VAL A 945 ? O VAL C 945 
AA4 10 11 N LEU A 946 ? N LEU C 946 O LYS A 973 ? O LYS C 973 
# 
_pdbx_entry_details.entry_id                   9MIG 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 LEU C 164  ? ? 65.78   117.47  
2  1 HIS C 215  ? ? 72.39   -23.49  
3  1 LYS C 289  ? ? -106.37 -130.00 
4  1 SER C 295  ? ? 83.74   -11.12  
5  1 CYS C 319  ? ? 65.18   77.72   
6  1 ASP C 321  ? ? 79.78   99.52   
7  1 GLU C 343  ? ? 72.54   -1.89   
8  1 ASP C 363  ? ? 64.34   -67.65  
9  1 GLN C 434  ? ? -162.11 103.52  
10 1 ALA C 497  ? ? -163.26 -88.21  
11 1 SER C 555  ? ? -158.62 -67.90  
12 1 TYR C 572  ? ? 67.84   -24.47  
13 1 THR C 589  ? ? -125.39 -167.90 
14 1 TYR C 591  ? ? 77.07   94.59   
15 1 LEU C 592  ? ? 72.40   -49.97  
16 1 LEU C 684  ? ? -113.07 -164.91 
17 1 HIS C 685  ? ? -68.00  86.05   
18 1 SER C 727  ? ? -163.80 -163.04 
19 1 ALA C 809  ? ? -107.72 42.61   
20 1 ALA C 866  ? ? -99.91  39.77   
21 1 ASN C 950  ? ? -24.24  96.38   
22 1 THR C 1029 ? ? -45.47  -74.04  
23 1 PHE C 1032 ? ? 71.17   55.28   
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9MIG 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9MIG 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.6 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               157467 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'NLRP3 hexamer' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9MIG 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS GLACIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            200 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             2400 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9MIG 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9MIG 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 C MET 1    ? A MET 1    
2   1 Y 1 C LYS 2    ? A LYS 2    
3   1 Y 1 C MET 3    ? A MET 3    
4   1 Y 1 C ALA 4    ? A ALA 4    
5   1 Y 1 C SER 5    ? A SER 5    
6   1 Y 1 C THR 6    ? A THR 6    
7   1 Y 1 C ARG 7    ? A ARG 7    
8   1 Y 1 C CYS 8    ? A CYS 8    
9   1 Y 1 C LYS 9    ? A LYS 9    
10  1 Y 1 C LEU 10   ? A LEU 10   
11  1 Y 1 C ALA 11   ? A ALA 11   
12  1 Y 1 C ARG 12   ? A ARG 12   
13  1 Y 1 C TYR 13   ? A TYR 13   
14  1 Y 1 C LEU 14   ? A LEU 14   
15  1 Y 1 C GLU 15   ? A GLU 15   
16  1 Y 1 C ASP 16   ? A ASP 16   
17  1 Y 1 C LEU 17   ? A LEU 17   
18  1 Y 1 C GLU 18   ? A GLU 18   
19  1 Y 1 C ASP 19   ? A ASP 19   
20  1 Y 1 C VAL 20   ? A VAL 20   
21  1 Y 1 C ASP 21   ? A ASP 21   
22  1 Y 1 C LEU 22   ? A LEU 22   
23  1 Y 1 C LYS 23   ? A LYS 23   
24  1 Y 1 C LYS 24   ? A LYS 24   
25  1 Y 1 C PHE 25   ? A PHE 25   
26  1 Y 1 C LYS 26   ? A LYS 26   
27  1 Y 1 C MET 27   ? A MET 27   
28  1 Y 1 C HIS 28   ? A HIS 28   
29  1 Y 1 C LEU 29   ? A LEU 29   
30  1 Y 1 C GLU 30   ? A GLU 30   
31  1 Y 1 C ASP 31   ? A ASP 31   
32  1 Y 1 C TYR 32   ? A TYR 32   
33  1 Y 1 C PRO 33   ? A PRO 33   
34  1 Y 1 C PRO 34   ? A PRO 34   
35  1 Y 1 C GLN 35   ? A GLN 35   
36  1 Y 1 C LYS 36   ? A LYS 36   
37  1 Y 1 C GLY 37   ? A GLY 37   
38  1 Y 1 C CYS 38   ? A CYS 38   
39  1 Y 1 C ILE 39   ? A ILE 39   
40  1 Y 1 C PRO 40   ? A PRO 40   
41  1 Y 1 C LEU 41   ? A LEU 41   
42  1 Y 1 C PRO 42   ? A PRO 42   
43  1 Y 1 C ARG 43   ? A ARG 43   
44  1 Y 1 C GLY 44   ? A GLY 44   
45  1 Y 1 C GLN 45   ? A GLN 45   
46  1 Y 1 C THR 46   ? A THR 46   
47  1 Y 1 C GLU 47   ? A GLU 47   
48  1 Y 1 C LYS 48   ? A LYS 48   
49  1 Y 1 C ALA 49   ? A ALA 49   
50  1 Y 1 C ASP 50   ? A ASP 50   
51  1 Y 1 C HIS 51   ? A HIS 51   
52  1 Y 1 C VAL 52   ? A VAL 52   
53  1 Y 1 C ASP 53   ? A ASP 53   
54  1 Y 1 C LEU 54   ? A LEU 54   
55  1 Y 1 C ALA 55   ? A ALA 55   
56  1 Y 1 C THR 56   ? A THR 56   
57  1 Y 1 C LEU 57   ? A LEU 57   
58  1 Y 1 C MET 58   ? A MET 58   
59  1 Y 1 C ILE 59   ? A ILE 59   
60  1 Y 1 C ASP 60   ? A ASP 60   
61  1 Y 1 C PHE 61   ? A PHE 61   
62  1 Y 1 C ASN 62   ? A ASN 62   
63  1 Y 1 C GLY 63   ? A GLY 63   
64  1 Y 1 C GLU 64   ? A GLU 64   
65  1 Y 1 C GLU 65   ? A GLU 65   
66  1 Y 1 C LYS 66   ? A LYS 66   
67  1 Y 1 C ALA 67   ? A ALA 67   
68  1 Y 1 C TRP 68   ? A TRP 68   
69  1 Y 1 C ALA 69   ? A ALA 69   
70  1 Y 1 C MET 70   ? A MET 70   
71  1 Y 1 C ALA 71   ? A ALA 71   
72  1 Y 1 C VAL 72   ? A VAL 72   
73  1 Y 1 C TRP 73   ? A TRP 73   
74  1 Y 1 C ILE 74   ? A ILE 74   
75  1 Y 1 C PHE 75   ? A PHE 75   
76  1 Y 1 C ALA 76   ? A ALA 76   
77  1 Y 1 C ALA 77   ? A ALA 77   
78  1 Y 1 C ILE 78   ? A ILE 78   
79  1 Y 1 C ASN 79   ? A ASN 79   
80  1 Y 1 C ARG 80   ? A ARG 80   
81  1 Y 1 C ARG 81   ? A ARG 81   
82  1 Y 1 C ASP 82   ? A ASP 82   
83  1 Y 1 C LEU 83   ? A LEU 83   
84  1 Y 1 C TYR 84   ? A TYR 84   
85  1 Y 1 C GLU 85   ? A GLU 85   
86  1 Y 1 C LYS 86   ? A LYS 86   
87  1 Y 1 C ALA 87   ? A ALA 87   
88  1 Y 1 C LYS 88   ? A LYS 88   
89  1 Y 1 C ARG 89   ? A ARG 89   
90  1 Y 1 C ASP 90   ? A ASP 90   
91  1 Y 1 C GLU 91   ? A GLU 91   
92  1 Y 1 C PRO 92   ? A PRO 92   
93  1 Y 1 C LYS 93   ? A LYS 93   
94  1 Y 1 C TRP 94   ? A TRP 94   
95  1 Y 1 C GLY 95   ? A GLY 95   
96  1 Y 1 C SER 96   ? A SER 96   
97  1 Y 1 C ASP 97   ? A ASP 97   
98  1 Y 1 C ASN 98   ? A ASN 98   
99  1 Y 1 C ALA 99   ? A ALA 99   
100 1 Y 1 C ARG 100  ? A ARG 100  
101 1 Y 1 C VAL 101  ? A VAL 101  
102 1 Y 1 C SER 102  ? A SER 102  
103 1 Y 1 C ASN 103  ? A ASN 103  
104 1 Y 1 C PRO 104  ? A PRO 104  
105 1 Y 1 C THR 105  ? A THR 105  
106 1 Y 1 C VAL 106  ? A VAL 106  
107 1 Y 1 C ILE 107  ? A ILE 107  
108 1 Y 1 C CYS 108  ? A CYS 108  
109 1 Y 1 C GLN 109  ? A GLN 109  
110 1 Y 1 C GLU 110  ? A GLU 110  
111 1 Y 1 C ASP 111  ? A ASP 111  
112 1 Y 1 C SER 112  ? A SER 112  
113 1 Y 1 C ILE 113  ? A ILE 113  
114 1 Y 1 C GLU 114  ? A GLU 114  
115 1 Y 1 C GLU 115  ? A GLU 115  
116 1 Y 1 C GLU 116  ? A GLU 116  
117 1 Y 1 C TRP 117  ? A TRP 117  
118 1 Y 1 C MET 118  ? A MET 118  
119 1 Y 1 C GLY 119  ? A GLY 119  
120 1 Y 1 C LEU 120  ? A LEU 120  
121 1 Y 1 C LEU 121  ? A LEU 121  
122 1 Y 1 C GLU 122  ? A GLU 122  
123 1 Y 1 C TYR 123  ? A TYR 123  
124 1 Y 1 C LEU 124  ? A LEU 124  
125 1 Y 1 C SER 125  ? A SER 125  
126 1 Y 1 C ARG 126  ? A ARG 126  
127 1 Y 1 C ILE 127  ? A ILE 127  
128 1 Y 1 C SER 128  ? A SER 128  
129 1 Y 1 C ILE 129  ? A ILE 129  
130 1 Y 1 C CYS 130  ? A CYS 130  
131 1 Y 1 C LYS 131  ? A LYS 131  
132 1 Y 1 C MET 132  ? A MET 132  
133 1 Y 1 C HIS 177  ? A HIS 177  
134 1 Y 1 C ARG 178  ? A ARG 178  
135 1 Y 1 C SER 179  ? A SER 179  
136 1 Y 1 C GLN 180  ? A GLN 180  
137 1 Y 1 C GLN 181  ? A GLN 181  
138 1 Y 1 C GLU 182  ? A GLU 182  
139 1 Y 1 C ARG 183  ? A ARG 183  
140 1 Y 1 C GLU 184  ? A GLU 184  
141 1 Y 1 C GLN 185  ? A GLN 185  
142 1 Y 1 C GLU 186  ? A GLU 186  
143 1 Y 1 C LEU 187  ? A LEU 187  
144 1 Y 1 C LEU 188  ? A LEU 188  
145 1 Y 1 C ALA 189  ? A ALA 189  
146 1 Y 1 C ILE 190  ? A ILE 190  
147 1 Y 1 C GLY 191  ? A GLY 191  
148 1 Y 1 C LYS 192  ? A LYS 192  
149 1 Y 1 C THR 193  ? A THR 193  
150 1 Y 1 C LYS 194  ? A LYS 194  
151 1 Y 1 C THR 195  ? A THR 195  
152 1 Y 1 C CYS 196  ? A CYS 196  
153 1 Y 1 C GLU 197  ? A GLU 197  
154 1 Y 1 C SER 198  ? A SER 198  
155 1 Y 1 C PRO 199  ? A PRO 199  
156 1 Y 1 C VAL 200  ? A VAL 200  
157 1 Y 1 C ARG 454  ? A ARG 454  
158 1 Y 1 C GLY 455  ? A GLY 455  
159 1 Y 1 C GLY 456  ? A GLY 456  
160 1 Y 1 C SER 457  ? A SER 457  
161 1 Y 1 C GLN 458  ? A GLN 458  
162 1 Y 1 C GLU 459  ? A GLU 459  
163 1 Y 1 C HIS 460  ? A HIS 460  
164 1 Y 1 C GLY 461  ? A GLY 461  
165 1 Y 1 C GLU 538  ? A GLU 538  
166 1 Y 1 C GLU 539  ? A GLU 539  
167 1 Y 1 C LYS 540  ? A LYS 540  
168 1 Y 1 C GLU 541  ? A GLU 541  
169 1 Y 1 C GLY 542  ? A GLY 542  
170 1 Y 1 C ARG 543  ? A ARG 543  
171 1 Y 1 C THR 544  ? A THR 544  
172 1 Y 1 C ASN 545  ? A ASN 545  
173 1 Y 1 C VAL 546  ? A VAL 546  
174 1 Y 1 C PRO 547  ? A PRO 547  
175 1 Y 1 C GLY 548  ? A GLY 548  
176 1 Y 1 C SER 549  ? A SER 549  
177 1 Y 1 C ARG 550  ? A ARG 550  
178 1 Y 1 C LEU 551  ? A LEU 551  
179 1 Y 1 C LYS 552  ? A LYS 552  
180 1 Y 1 C MET 687  ? A MET 687  
181 1 Y 1 C PRO 688  ? A PRO 688  
182 1 Y 1 C LYS 689  ? A LYS 689  
183 1 Y 1 C GLU 690  ? A GLU 690  
184 1 Y 1 C GLU 691  ? A GLU 691  
185 1 Y 1 C GLU 692  ? A GLU 692  
186 1 Y 1 C GLU 693  ? A GLU 693  
187 1 Y 1 C GLU 694  ? A GLU 694  
188 1 Y 1 C GLU 695  ? A GLU 695  
189 1 Y 1 C LYS 696  ? A LYS 696  
190 1 Y 1 C GLU 697  ? A GLU 697  
191 1 Y 1 C GLY 698  ? A GLY 698  
192 1 Y 1 C ARG 699  ? A ARG 699  
193 1 Y 1 C HIS 700  ? A HIS 700  
194 1 Y 1 C LEU 701  ? A LEU 701  
195 1 Y 1 C ASP 702  ? A ASP 702  
196 1 Y 1 C MET 703  ? A MET 703  
197 1 Y 1 C VAL 704  ? A VAL 704  
198 1 Y 1 C GLN 705  ? A GLN 705  
199 1 Y 1 C CYS 706  ? A CYS 706  
200 1 Y 1 C VAL 707  ? A VAL 707  
201 1 Y 1 C LEU 708  ? A LEU 708  
202 1 Y 1 C PRO 709  ? A PRO 709  
203 1 Y 1 C SER 710  ? A SER 710  
204 1 Y 1 C SER 711  ? A SER 711  
205 1 Y 1 C SER 712  ? A SER 712  
206 1 Y 1 C HIS 713  ? A HIS 713  
207 1 Y 1 C ALA 714  ? A ALA 714  
208 1 Y 1 C ALA 715  ? A ALA 715  
209 1 Y 1 C CYS 716  ? A CYS 716  
210 1 Y 1 C SER 717  ? A SER 717  
211 1 Y 1 C HIS 718  ? A HIS 718  
212 1 Y 1 C GLY 719  ? A GLY 719  
213 1 Y 1 C LEU 720  ? A LEU 720  
214 1 Y 1 C VAL 721  ? A VAL 721  
215 1 Y 1 C ASN 722  ? A ASN 722  
216 1 Y 1 C SER 723  ? A SER 723  
217 1 Y 1 C HIS 724  ? A HIS 724  
218 1 Y 1 C TRP 1036 ? A TRP 1036 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1BLQ N1     N N N 1   
A1BLQ N3     N Y N 2   
A1BLQ C4     C N N 3   
A1BLQ C5     C N R 4   
A1BLQ C6     C N N 5   
A1BLQ C7     C Y N 6   
A1BLQ C8     C Y N 7   
A1BLQ C10    C Y N 8   
A1BLQ C13    C Y N 9   
A1BLQ C15    C N N 10  
A1BLQ C17    C N N 11  
A1BLQ C20    C N N 12  
A1BLQ C21    C Y N 13  
A1BLQ C1     C N N 14  
A1BLQ C2     C N N 15  
A1BLQ C3     C N N 16  
A1BLQ N2     N N N 17  
A1BLQ N4     N Y N 18  
A1BLQ C9     C Y N 19  
A1BLQ C11    C Y N 20  
A1BLQ C12    C Y N 21  
A1BLQ C14    C Y N 22  
A1BLQ O1     O N N 23  
A1BLQ F1     F N N 24  
A1BLQ F2     F N N 25  
A1BLQ F3     F N N 26  
A1BLQ C16    C Y N 27  
A1BLQ C18    C N N 28  
A1BLQ C19    C N N 29  
A1BLQ H8     H N N 30  
A1BLQ H9     H N N 31  
A1BLQ H10    H N N 32  
A1BLQ H11    H N N 33  
A1BLQ H12    H N N 34  
A1BLQ H14    H N N 35  
A1BLQ H16    H N N 36  
A1BLQ H19    H N N 37  
A1BLQ H18    H N N 38  
A1BLQ H25    H N N 39  
A1BLQ H24    H N N 40  
A1BLQ H3     H N N 41  
A1BLQ H1     H N N 42  
A1BLQ H2     H N N 43  
A1BLQ H5     H N N 44  
A1BLQ H4     H N N 45  
A1BLQ H6     H N N 46  
A1BLQ H7     H N N 47  
A1BLQ H13    H N N 48  
A1BLQ H15    H N N 49  
A1BLQ H17    H N N 50  
A1BLQ H20    H N N 51  
A1BLQ H21    H N N 52  
A1BLQ H23    H N N 53  
A1BLQ H22    H N N 54  
ALA   N      N N N 55  
ALA   CA     C N S 56  
ALA   C      C N N 57  
ALA   O      O N N 58  
ALA   CB     C N N 59  
ALA   OXT    O N N 60  
ALA   H      H N N 61  
ALA   H2     H N N 62  
ALA   HA     H N N 63  
ALA   HB1    H N N 64  
ALA   HB2    H N N 65  
ALA   HB3    H N N 66  
ALA   HXT    H N N 67  
ARG   N      N N N 68  
ARG   CA     C N S 69  
ARG   C      C N N 70  
ARG   O      O N N 71  
ARG   CB     C N N 72  
ARG   CG     C N N 73  
ARG   CD     C N N 74  
ARG   NE     N N N 75  
ARG   CZ     C N N 76  
ARG   NH1    N N N 77  
ARG   NH2    N N N 78  
ARG   OXT    O N N 79  
ARG   H      H N N 80  
ARG   H2     H N N 81  
ARG   HA     H N N 82  
ARG   HB2    H N N 83  
ARG   HB3    H N N 84  
ARG   HG2    H N N 85  
ARG   HG3    H N N 86  
ARG   HD2    H N N 87  
ARG   HD3    H N N 88  
ARG   HE     H N N 89  
ARG   HH11   H N N 90  
ARG   HH12   H N N 91  
ARG   HH21   H N N 92  
ARG   HH22   H N N 93  
ARG   HXT    H N N 94  
ASN   N      N N N 95  
ASN   CA     C N S 96  
ASN   C      C N N 97  
ASN   O      O N N 98  
ASN   CB     C N N 99  
ASN   CG     C N N 100 
ASN   OD1    O N N 101 
ASN   ND2    N N N 102 
ASN   OXT    O N N 103 
ASN   H      H N N 104 
ASN   H2     H N N 105 
ASN   HA     H N N 106 
ASN   HB2    H N N 107 
ASN   HB3    H N N 108 
ASN   HD21   H N N 109 
ASN   HD22   H N N 110 
ASN   HXT    H N N 111 
ASP   N      N N N 112 
ASP   CA     C N S 113 
ASP   C      C N N 114 
ASP   O      O N N 115 
ASP   CB     C N N 116 
ASP   CG     C N N 117 
ASP   OD1    O N N 118 
ASP   OD2    O N N 119 
ASP   OXT    O N N 120 
ASP   H      H N N 121 
ASP   H2     H N N 122 
ASP   HA     H N N 123 
ASP   HB2    H N N 124 
ASP   HB3    H N N 125 
ASP   HD2    H N N 126 
ASP   HXT    H N N 127 
ATP   PG     P N N 128 
ATP   O1G    O N N 129 
ATP   O2G    O N N 130 
ATP   O3G    O N N 131 
ATP   PB     P N R 132 
ATP   O1B    O N N 133 
ATP   O2B    O N N 134 
ATP   O3B    O N N 135 
ATP   PA     P N R 136 
ATP   O1A    O N N 137 
ATP   O2A    O N N 138 
ATP   O3A    O N N 139 
ATP   "O5'"  O N N 140 
ATP   "C5'"  C N N 141 
ATP   "C4'"  C N R 142 
ATP   "O4'"  O N N 143 
ATP   "C3'"  C N S 144 
ATP   "O3'"  O N N 145 
ATP   "C2'"  C N R 146 
ATP   "O2'"  O N N 147 
ATP   "C1'"  C N R 148 
ATP   N9     N Y N 149 
ATP   C8     C Y N 150 
ATP   N7     N Y N 151 
ATP   C5     C Y N 152 
ATP   C6     C Y N 153 
ATP   N6     N N N 154 
ATP   N1     N Y N 155 
ATP   C2     C Y N 156 
ATP   N3     N Y N 157 
ATP   C4     C Y N 158 
ATP   HOG2   H N N 159 
ATP   HOG3   H N N 160 
ATP   HOB2   H N N 161 
ATP   HOA2   H N N 162 
ATP   "H5'1" H N N 163 
ATP   "H5'2" H N N 164 
ATP   "H4'"  H N N 165 
ATP   "H3'"  H N N 166 
ATP   "HO3'" H N N 167 
ATP   "H2'"  H N N 168 
ATP   "HO2'" H N N 169 
ATP   "H1'"  H N N 170 
ATP   H8     H N N 171 
ATP   HN61   H N N 172 
ATP   HN62   H N N 173 
ATP   H2     H N N 174 
CYS   N      N N N 175 
CYS   CA     C N R 176 
CYS   C      C N N 177 
CYS   O      O N N 178 
CYS   CB     C N N 179 
CYS   SG     S N N 180 
CYS   OXT    O N N 181 
CYS   H      H N N 182 
CYS   H2     H N N 183 
CYS   HA     H N N 184 
CYS   HB2    H N N 185 
CYS   HB3    H N N 186 
CYS   HG     H N N 187 
CYS   HXT    H N N 188 
GLN   N      N N N 189 
GLN   CA     C N S 190 
GLN   C      C N N 191 
GLN   O      O N N 192 
GLN   CB     C N N 193 
GLN   CG     C N N 194 
GLN   CD     C N N 195 
GLN   OE1    O N N 196 
GLN   NE2    N N N 197 
GLN   OXT    O N N 198 
GLN   H      H N N 199 
GLN   H2     H N N 200 
GLN   HA     H N N 201 
GLN   HB2    H N N 202 
GLN   HB3    H N N 203 
GLN   HG2    H N N 204 
GLN   HG3    H N N 205 
GLN   HE21   H N N 206 
GLN   HE22   H N N 207 
GLN   HXT    H N N 208 
GLU   N      N N N 209 
GLU   CA     C N S 210 
GLU   C      C N N 211 
GLU   O      O N N 212 
GLU   CB     C N N 213 
GLU   CG     C N N 214 
GLU   CD     C N N 215 
GLU   OE1    O N N 216 
GLU   OE2    O N N 217 
GLU   OXT    O N N 218 
GLU   H      H N N 219 
GLU   H2     H N N 220 
GLU   HA     H N N 221 
GLU   HB2    H N N 222 
GLU   HB3    H N N 223 
GLU   HG2    H N N 224 
GLU   HG3    H N N 225 
GLU   HE2    H N N 226 
GLU   HXT    H N N 227 
GLY   N      N N N 228 
GLY   CA     C N N 229 
GLY   C      C N N 230 
GLY   O      O N N 231 
GLY   OXT    O N N 232 
GLY   H      H N N 233 
GLY   H2     H N N 234 
GLY   HA2    H N N 235 
GLY   HA3    H N N 236 
GLY   HXT    H N N 237 
HIS   N      N N N 238 
HIS   CA     C N S 239 
HIS   C      C N N 240 
HIS   O      O N N 241 
HIS   CB     C N N 242 
HIS   CG     C Y N 243 
HIS   ND1    N Y N 244 
HIS   CD2    C Y N 245 
HIS   CE1    C Y N 246 
HIS   NE2    N Y N 247 
HIS   OXT    O N N 248 
HIS   H      H N N 249 
HIS   H2     H N N 250 
HIS   HA     H N N 251 
HIS   HB2    H N N 252 
HIS   HB3    H N N 253 
HIS   HD1    H N N 254 
HIS   HD2    H N N 255 
HIS   HE1    H N N 256 
HIS   HE2    H N N 257 
HIS   HXT    H N N 258 
ILE   N      N N N 259 
ILE   CA     C N S 260 
ILE   C      C N N 261 
ILE   O      O N N 262 
ILE   CB     C N S 263 
ILE   CG1    C N N 264 
ILE   CG2    C N N 265 
ILE   CD1    C N N 266 
ILE   OXT    O N N 267 
ILE   H      H N N 268 
ILE   H2     H N N 269 
ILE   HA     H N N 270 
ILE   HB     H N N 271 
ILE   HG12   H N N 272 
ILE   HG13   H N N 273 
ILE   HG21   H N N 274 
ILE   HG22   H N N 275 
ILE   HG23   H N N 276 
ILE   HD11   H N N 277 
ILE   HD12   H N N 278 
ILE   HD13   H N N 279 
ILE   HXT    H N N 280 
LEU   N      N N N 281 
LEU   CA     C N S 282 
LEU   C      C N N 283 
LEU   O      O N N 284 
LEU   CB     C N N 285 
LEU   CG     C N N 286 
LEU   CD1    C N N 287 
LEU   CD2    C N N 288 
LEU   OXT    O N N 289 
LEU   H      H N N 290 
LEU   H2     H N N 291 
LEU   HA     H N N 292 
LEU   HB2    H N N 293 
LEU   HB3    H N N 294 
LEU   HG     H N N 295 
LEU   HD11   H N N 296 
LEU   HD12   H N N 297 
LEU   HD13   H N N 298 
LEU   HD21   H N N 299 
LEU   HD22   H N N 300 
LEU   HD23   H N N 301 
LEU   HXT    H N N 302 
LYS   N      N N N 303 
LYS   CA     C N S 304 
LYS   C      C N N 305 
LYS   O      O N N 306 
LYS   CB     C N N 307 
LYS   CG     C N N 308 
LYS   CD     C N N 309 
LYS   CE     C N N 310 
LYS   NZ     N N N 311 
LYS   OXT    O N N 312 
LYS   H      H N N 313 
LYS   H2     H N N 314 
LYS   HA     H N N 315 
LYS   HB2    H N N 316 
LYS   HB3    H N N 317 
LYS   HG2    H N N 318 
LYS   HG3    H N N 319 
LYS   HD2    H N N 320 
LYS   HD3    H N N 321 
LYS   HE2    H N N 322 
LYS   HE3    H N N 323 
LYS   HZ1    H N N 324 
LYS   HZ2    H N N 325 
LYS   HZ3    H N N 326 
LYS   HXT    H N N 327 
MET   N      N N N 328 
MET   CA     C N S 329 
MET   C      C N N 330 
MET   O      O N N 331 
MET   CB     C N N 332 
MET   CG     C N N 333 
MET   SD     S N N 334 
MET   CE     C N N 335 
MET   OXT    O N N 336 
MET   H      H N N 337 
MET   H2     H N N 338 
MET   HA     H N N 339 
MET   HB2    H N N 340 
MET   HB3    H N N 341 
MET   HG2    H N N 342 
MET   HG3    H N N 343 
MET   HE1    H N N 344 
MET   HE2    H N N 345 
MET   HE3    H N N 346 
MET   HXT    H N N 347 
PHE   N      N N N 348 
PHE   CA     C N S 349 
PHE   C      C N N 350 
PHE   O      O N N 351 
PHE   CB     C N N 352 
PHE   CG     C Y N 353 
PHE   CD1    C Y N 354 
PHE   CD2    C Y N 355 
PHE   CE1    C Y N 356 
PHE   CE2    C Y N 357 
PHE   CZ     C Y N 358 
PHE   OXT    O N N 359 
PHE   H      H N N 360 
PHE   H2     H N N 361 
PHE   HA     H N N 362 
PHE   HB2    H N N 363 
PHE   HB3    H N N 364 
PHE   HD1    H N N 365 
PHE   HD2    H N N 366 
PHE   HE1    H N N 367 
PHE   HE2    H N N 368 
PHE   HZ     H N N 369 
PHE   HXT    H N N 370 
PRO   N      N N N 371 
PRO   CA     C N S 372 
PRO   C      C N N 373 
PRO   O      O N N 374 
PRO   CB     C N N 375 
PRO   CG     C N N 376 
PRO   CD     C N N 377 
PRO   OXT    O N N 378 
PRO   H      H N N 379 
PRO   HA     H N N 380 
PRO   HB2    H N N 381 
PRO   HB3    H N N 382 
PRO   HG2    H N N 383 
PRO   HG3    H N N 384 
PRO   HD2    H N N 385 
PRO   HD3    H N N 386 
PRO   HXT    H N N 387 
SER   N      N N N 388 
SER   CA     C N S 389 
SER   C      C N N 390 
SER   O      O N N 391 
SER   CB     C N N 392 
SER   OG     O N N 393 
SER   OXT    O N N 394 
SER   H      H N N 395 
SER   H2     H N N 396 
SER   HA     H N N 397 
SER   HB2    H N N 398 
SER   HB3    H N N 399 
SER   HG     H N N 400 
SER   HXT    H N N 401 
THR   N      N N N 402 
THR   CA     C N S 403 
THR   C      C N N 404 
THR   O      O N N 405 
THR   CB     C N R 406 
THR   OG1    O N N 407 
THR   CG2    C N N 408 
THR   OXT    O N N 409 
THR   H      H N N 410 
THR   H2     H N N 411 
THR   HA     H N N 412 
THR   HB     H N N 413 
THR   HG1    H N N 414 
THR   HG21   H N N 415 
THR   HG22   H N N 416 
THR   HG23   H N N 417 
THR   HXT    H N N 418 
TRP   N      N N N 419 
TRP   CA     C N S 420 
TRP   C      C N N 421 
TRP   O      O N N 422 
TRP   CB     C N N 423 
TRP   CG     C Y N 424 
TRP   CD1    C Y N 425 
TRP   CD2    C Y N 426 
TRP   NE1    N Y N 427 
TRP   CE2    C Y N 428 
TRP   CE3    C Y N 429 
TRP   CZ2    C Y N 430 
TRP   CZ3    C Y N 431 
TRP   CH2    C Y N 432 
TRP   OXT    O N N 433 
TRP   H      H N N 434 
TRP   H2     H N N 435 
TRP   HA     H N N 436 
TRP   HB2    H N N 437 
TRP   HB3    H N N 438 
TRP   HD1    H N N 439 
TRP   HE1    H N N 440 
TRP   HE3    H N N 441 
TRP   HZ2    H N N 442 
TRP   HZ3    H N N 443 
TRP   HH2    H N N 444 
TRP   HXT    H N N 445 
TYR   N      N N N 446 
TYR   CA     C N S 447 
TYR   C      C N N 448 
TYR   O      O N N 449 
TYR   CB     C N N 450 
TYR   CG     C Y N 451 
TYR   CD1    C Y N 452 
TYR   CD2    C Y N 453 
TYR   CE1    C Y N 454 
TYR   CE2    C Y N 455 
TYR   CZ     C Y N 456 
TYR   OH     O N N 457 
TYR   OXT    O N N 458 
TYR   H      H N N 459 
TYR   H2     H N N 460 
TYR   HA     H N N 461 
TYR   HB2    H N N 462 
TYR   HB3    H N N 463 
TYR   HD1    H N N 464 
TYR   HD2    H N N 465 
TYR   HE1    H N N 466 
TYR   HE2    H N N 467 
TYR   HH     H N N 468 
TYR   HXT    H N N 469 
VAL   N      N N N 470 
VAL   CA     C N S 471 
VAL   C      C N N 472 
VAL   O      O N N 473 
VAL   CB     C N N 474 
VAL   CG1    C N N 475 
VAL   CG2    C N N 476 
VAL   OXT    O N N 477 
VAL   H      H N N 478 
VAL   H2     H N N 479 
VAL   HA     H N N 480 
VAL   HB     H N N 481 
VAL   HG11   H N N 482 
VAL   HG12   H N N 483 
VAL   HG13   H N N 484 
VAL   HG21   H N N 485 
VAL   HG22   H N N 486 
VAL   HG23   H N N 487 
VAL   HXT    H N N 488 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1BLQ C1    N1     sing N N 1   
A1BLQ N1    C2     sing N N 2   
A1BLQ N1    C6     sing N N 3   
A1BLQ C2    C3     sing N N 4   
A1BLQ C6    C5     sing N N 5   
A1BLQ F3    C15    sing N N 6   
A1BLQ F1    C15    sing N N 7   
A1BLQ C3    C4     sing N N 8   
A1BLQ C15   C12    sing N N 9   
A1BLQ C15   F2     sing N N 10  
A1BLQ N4    N3     doub Y N 11  
A1BLQ N4    C8     sing Y N 12  
A1BLQ N3    C7     sing Y N 13  
A1BLQ C13   C12    doub Y N 14  
A1BLQ C13   C14    sing Y N 15  
A1BLQ C5    C4     sing N N 16  
A1BLQ C5    N2     sing N N 17  
A1BLQ C12   C11    sing Y N 18  
A1BLQ O1    C14    sing N N 19  
A1BLQ C14   C9     doub Y N 20  
A1BLQ C11   C10    doub Y N 21  
A1BLQ C9    C10    sing Y N 22  
A1BLQ C9    C8     sing N N 23  
A1BLQ C8    C16    doub Y N 24  
A1BLQ N2    C7     sing N N 25  
A1BLQ C7    C21    doub Y N 26  
A1BLQ C16   C21    sing Y N 27  
A1BLQ C16   C17    sing N N 28  
A1BLQ C21   C20    sing N N 29  
A1BLQ C17   C18    sing N N 30  
A1BLQ C20   C19    sing N N 31  
A1BLQ C19   C18    sing N N 32  
A1BLQ C4    H8     sing N N 33  
A1BLQ C4    H9     sing N N 34  
A1BLQ C5    H10    sing N N 35  
A1BLQ C6    H11    sing N N 36  
A1BLQ C6    H12    sing N N 37  
A1BLQ C10   H14    sing N N 38  
A1BLQ C13   H16    sing N N 39  
A1BLQ C17   H19    sing N N 40  
A1BLQ C17   H18    sing N N 41  
A1BLQ C20   H25    sing N N 42  
A1BLQ C20   H24    sing N N 43  
A1BLQ C1    H3     sing N N 44  
A1BLQ C1    H1     sing N N 45  
A1BLQ C1    H2     sing N N 46  
A1BLQ C2    H5     sing N N 47  
A1BLQ C2    H4     sing N N 48  
A1BLQ C3    H6     sing N N 49  
A1BLQ C3    H7     sing N N 50  
A1BLQ N2    H13    sing N N 51  
A1BLQ C11   H15    sing N N 52  
A1BLQ O1    H17    sing N N 53  
A1BLQ C18   H20    sing N N 54  
A1BLQ C18   H21    sing N N 55  
A1BLQ C19   H23    sing N N 56  
A1BLQ C19   H22    sing N N 57  
ALA   N     CA     sing N N 58  
ALA   N     H      sing N N 59  
ALA   N     H2     sing N N 60  
ALA   CA    C      sing N N 61  
ALA   CA    CB     sing N N 62  
ALA   CA    HA     sing N N 63  
ALA   C     O      doub N N 64  
ALA   C     OXT    sing N N 65  
ALA   CB    HB1    sing N N 66  
ALA   CB    HB2    sing N N 67  
ALA   CB    HB3    sing N N 68  
ALA   OXT   HXT    sing N N 69  
ARG   N     CA     sing N N 70  
ARG   N     H      sing N N 71  
ARG   N     H2     sing N N 72  
ARG   CA    C      sing N N 73  
ARG   CA    CB     sing N N 74  
ARG   CA    HA     sing N N 75  
ARG   C     O      doub N N 76  
ARG   C     OXT    sing N N 77  
ARG   CB    CG     sing N N 78  
ARG   CB    HB2    sing N N 79  
ARG   CB    HB3    sing N N 80  
ARG   CG    CD     sing N N 81  
ARG   CG    HG2    sing N N 82  
ARG   CG    HG3    sing N N 83  
ARG   CD    NE     sing N N 84  
ARG   CD    HD2    sing N N 85  
ARG   CD    HD3    sing N N 86  
ARG   NE    CZ     sing N N 87  
ARG   NE    HE     sing N N 88  
ARG   CZ    NH1    sing N N 89  
ARG   CZ    NH2    doub N N 90  
ARG   NH1   HH11   sing N N 91  
ARG   NH1   HH12   sing N N 92  
ARG   NH2   HH21   sing N N 93  
ARG   NH2   HH22   sing N N 94  
ARG   OXT   HXT    sing N N 95  
ASN   N     CA     sing N N 96  
ASN   N     H      sing N N 97  
ASN   N     H2     sing N N 98  
ASN   CA    C      sing N N 99  
ASN   CA    CB     sing N N 100 
ASN   CA    HA     sing N N 101 
ASN   C     O      doub N N 102 
ASN   C     OXT    sing N N 103 
ASN   CB    CG     sing N N 104 
ASN   CB    HB2    sing N N 105 
ASN   CB    HB3    sing N N 106 
ASN   CG    OD1    doub N N 107 
ASN   CG    ND2    sing N N 108 
ASN   ND2   HD21   sing N N 109 
ASN   ND2   HD22   sing N N 110 
ASN   OXT   HXT    sing N N 111 
ASP   N     CA     sing N N 112 
ASP   N     H      sing N N 113 
ASP   N     H2     sing N N 114 
ASP   CA    C      sing N N 115 
ASP   CA    CB     sing N N 116 
ASP   CA    HA     sing N N 117 
ASP   C     O      doub N N 118 
ASP   C     OXT    sing N N 119 
ASP   CB    CG     sing N N 120 
ASP   CB    HB2    sing N N 121 
ASP   CB    HB3    sing N N 122 
ASP   CG    OD1    doub N N 123 
ASP   CG    OD2    sing N N 124 
ASP   OD2   HD2    sing N N 125 
ASP   OXT   HXT    sing N N 126 
ATP   PG    O1G    doub N N 127 
ATP   PG    O2G    sing N N 128 
ATP   PG    O3G    sing N N 129 
ATP   PG    O3B    sing N N 130 
ATP   O2G   HOG2   sing N N 131 
ATP   O3G   HOG3   sing N N 132 
ATP   PB    O1B    doub N N 133 
ATP   PB    O2B    sing N N 134 
ATP   PB    O3B    sing N N 135 
ATP   PB    O3A    sing N N 136 
ATP   O2B   HOB2   sing N N 137 
ATP   PA    O1A    doub N N 138 
ATP   PA    O2A    sing N N 139 
ATP   PA    O3A    sing N N 140 
ATP   PA    "O5'"  sing N N 141 
ATP   O2A   HOA2   sing N N 142 
ATP   "O5'" "C5'"  sing N N 143 
ATP   "C5'" "C4'"  sing N N 144 
ATP   "C5'" "H5'1" sing N N 145 
ATP   "C5'" "H5'2" sing N N 146 
ATP   "C4'" "O4'"  sing N N 147 
ATP   "C4'" "C3'"  sing N N 148 
ATP   "C4'" "H4'"  sing N N 149 
ATP   "O4'" "C1'"  sing N N 150 
ATP   "C3'" "O3'"  sing N N 151 
ATP   "C3'" "C2'"  sing N N 152 
ATP   "C3'" "H3'"  sing N N 153 
ATP   "O3'" "HO3'" sing N N 154 
ATP   "C2'" "O2'"  sing N N 155 
ATP   "C2'" "C1'"  sing N N 156 
ATP   "C2'" "H2'"  sing N N 157 
ATP   "O2'" "HO2'" sing N N 158 
ATP   "C1'" N9     sing N N 159 
ATP   "C1'" "H1'"  sing N N 160 
ATP   N9    C8     sing Y N 161 
ATP   N9    C4     sing Y N 162 
ATP   C8    N7     doub Y N 163 
ATP   C8    H8     sing N N 164 
ATP   N7    C5     sing Y N 165 
ATP   C5    C6     sing Y N 166 
ATP   C5    C4     doub Y N 167 
ATP   C6    N6     sing N N 168 
ATP   C6    N1     doub Y N 169 
ATP   N6    HN61   sing N N 170 
ATP   N6    HN62   sing N N 171 
ATP   N1    C2     sing Y N 172 
ATP   C2    N3     doub Y N 173 
ATP   C2    H2     sing N N 174 
ATP   N3    C4     sing Y N 175 
CYS   N     CA     sing N N 176 
CYS   N     H      sing N N 177 
CYS   N     H2     sing N N 178 
CYS   CA    C      sing N N 179 
CYS   CA    CB     sing N N 180 
CYS   CA    HA     sing N N 181 
CYS   C     O      doub N N 182 
CYS   C     OXT    sing N N 183 
CYS   CB    SG     sing N N 184 
CYS   CB    HB2    sing N N 185 
CYS   CB    HB3    sing N N 186 
CYS   SG    HG     sing N N 187 
CYS   OXT   HXT    sing N N 188 
GLN   N     CA     sing N N 189 
GLN   N     H      sing N N 190 
GLN   N     H2     sing N N 191 
GLN   CA    C      sing N N 192 
GLN   CA    CB     sing N N 193 
GLN   CA    HA     sing N N 194 
GLN   C     O      doub N N 195 
GLN   C     OXT    sing N N 196 
GLN   CB    CG     sing N N 197 
GLN   CB    HB2    sing N N 198 
GLN   CB    HB3    sing N N 199 
GLN   CG    CD     sing N N 200 
GLN   CG    HG2    sing N N 201 
GLN   CG    HG3    sing N N 202 
GLN   CD    OE1    doub N N 203 
GLN   CD    NE2    sing N N 204 
GLN   NE2   HE21   sing N N 205 
GLN   NE2   HE22   sing N N 206 
GLN   OXT   HXT    sing N N 207 
GLU   N     CA     sing N N 208 
GLU   N     H      sing N N 209 
GLU   N     H2     sing N N 210 
GLU   CA    C      sing N N 211 
GLU   CA    CB     sing N N 212 
GLU   CA    HA     sing N N 213 
GLU   C     O      doub N N 214 
GLU   C     OXT    sing N N 215 
GLU   CB    CG     sing N N 216 
GLU   CB    HB2    sing N N 217 
GLU   CB    HB3    sing N N 218 
GLU   CG    CD     sing N N 219 
GLU   CG    HG2    sing N N 220 
GLU   CG    HG3    sing N N 221 
GLU   CD    OE1    doub N N 222 
GLU   CD    OE2    sing N N 223 
GLU   OE2   HE2    sing N N 224 
GLU   OXT   HXT    sing N N 225 
GLY   N     CA     sing N N 226 
GLY   N     H      sing N N 227 
GLY   N     H2     sing N N 228 
GLY   CA    C      sing N N 229 
GLY   CA    HA2    sing N N 230 
GLY   CA    HA3    sing N N 231 
GLY   C     O      doub N N 232 
GLY   C     OXT    sing N N 233 
GLY   OXT   HXT    sing N N 234 
HIS   N     CA     sing N N 235 
HIS   N     H      sing N N 236 
HIS   N     H2     sing N N 237 
HIS   CA    C      sing N N 238 
HIS   CA    CB     sing N N 239 
HIS   CA    HA     sing N N 240 
HIS   C     O      doub N N 241 
HIS   C     OXT    sing N N 242 
HIS   CB    CG     sing N N 243 
HIS   CB    HB2    sing N N 244 
HIS   CB    HB3    sing N N 245 
HIS   CG    ND1    sing Y N 246 
HIS   CG    CD2    doub Y N 247 
HIS   ND1   CE1    doub Y N 248 
HIS   ND1   HD1    sing N N 249 
HIS   CD2   NE2    sing Y N 250 
HIS   CD2   HD2    sing N N 251 
HIS   CE1   NE2    sing Y N 252 
HIS   CE1   HE1    sing N N 253 
HIS   NE2   HE2    sing N N 254 
HIS   OXT   HXT    sing N N 255 
ILE   N     CA     sing N N 256 
ILE   N     H      sing N N 257 
ILE   N     H2     sing N N 258 
ILE   CA    C      sing N N 259 
ILE   CA    CB     sing N N 260 
ILE   CA    HA     sing N N 261 
ILE   C     O      doub N N 262 
ILE   C     OXT    sing N N 263 
ILE   CB    CG1    sing N N 264 
ILE   CB    CG2    sing N N 265 
ILE   CB    HB     sing N N 266 
ILE   CG1   CD1    sing N N 267 
ILE   CG1   HG12   sing N N 268 
ILE   CG1   HG13   sing N N 269 
ILE   CG2   HG21   sing N N 270 
ILE   CG2   HG22   sing N N 271 
ILE   CG2   HG23   sing N N 272 
ILE   CD1   HD11   sing N N 273 
ILE   CD1   HD12   sing N N 274 
ILE   CD1   HD13   sing N N 275 
ILE   OXT   HXT    sing N N 276 
LEU   N     CA     sing N N 277 
LEU   N     H      sing N N 278 
LEU   N     H2     sing N N 279 
LEU   CA    C      sing N N 280 
LEU   CA    CB     sing N N 281 
LEU   CA    HA     sing N N 282 
LEU   C     O      doub N N 283 
LEU   C     OXT    sing N N 284 
LEU   CB    CG     sing N N 285 
LEU   CB    HB2    sing N N 286 
LEU   CB    HB3    sing N N 287 
LEU   CG    CD1    sing N N 288 
LEU   CG    CD2    sing N N 289 
LEU   CG    HG     sing N N 290 
LEU   CD1   HD11   sing N N 291 
LEU   CD1   HD12   sing N N 292 
LEU   CD1   HD13   sing N N 293 
LEU   CD2   HD21   sing N N 294 
LEU   CD2   HD22   sing N N 295 
LEU   CD2   HD23   sing N N 296 
LEU   OXT   HXT    sing N N 297 
LYS   N     CA     sing N N 298 
LYS   N     H      sing N N 299 
LYS   N     H2     sing N N 300 
LYS   CA    C      sing N N 301 
LYS   CA    CB     sing N N 302 
LYS   CA    HA     sing N N 303 
LYS   C     O      doub N N 304 
LYS   C     OXT    sing N N 305 
LYS   CB    CG     sing N N 306 
LYS   CB    HB2    sing N N 307 
LYS   CB    HB3    sing N N 308 
LYS   CG    CD     sing N N 309 
LYS   CG    HG2    sing N N 310 
LYS   CG    HG3    sing N N 311 
LYS   CD    CE     sing N N 312 
LYS   CD    HD2    sing N N 313 
LYS   CD    HD3    sing N N 314 
LYS   CE    NZ     sing N N 315 
LYS   CE    HE2    sing N N 316 
LYS   CE    HE3    sing N N 317 
LYS   NZ    HZ1    sing N N 318 
LYS   NZ    HZ2    sing N N 319 
LYS   NZ    HZ3    sing N N 320 
LYS   OXT   HXT    sing N N 321 
MET   N     CA     sing N N 322 
MET   N     H      sing N N 323 
MET   N     H2     sing N N 324 
MET   CA    C      sing N N 325 
MET   CA    CB     sing N N 326 
MET   CA    HA     sing N N 327 
MET   C     O      doub N N 328 
MET   C     OXT    sing N N 329 
MET   CB    CG     sing N N 330 
MET   CB    HB2    sing N N 331 
MET   CB    HB3    sing N N 332 
MET   CG    SD     sing N N 333 
MET   CG    HG2    sing N N 334 
MET   CG    HG3    sing N N 335 
MET   SD    CE     sing N N 336 
MET   CE    HE1    sing N N 337 
MET   CE    HE2    sing N N 338 
MET   CE    HE3    sing N N 339 
MET   OXT   HXT    sing N N 340 
PHE   N     CA     sing N N 341 
PHE   N     H      sing N N 342 
PHE   N     H2     sing N N 343 
PHE   CA    C      sing N N 344 
PHE   CA    CB     sing N N 345 
PHE   CA    HA     sing N N 346 
PHE   C     O      doub N N 347 
PHE   C     OXT    sing N N 348 
PHE   CB    CG     sing N N 349 
PHE   CB    HB2    sing N N 350 
PHE   CB    HB3    sing N N 351 
PHE   CG    CD1    doub Y N 352 
PHE   CG    CD2    sing Y N 353 
PHE   CD1   CE1    sing Y N 354 
PHE   CD1   HD1    sing N N 355 
PHE   CD2   CE2    doub Y N 356 
PHE   CD2   HD2    sing N N 357 
PHE   CE1   CZ     doub Y N 358 
PHE   CE1   HE1    sing N N 359 
PHE   CE2   CZ     sing Y N 360 
PHE   CE2   HE2    sing N N 361 
PHE   CZ    HZ     sing N N 362 
PHE   OXT   HXT    sing N N 363 
PRO   N     CA     sing N N 364 
PRO   N     CD     sing N N 365 
PRO   N     H      sing N N 366 
PRO   CA    C      sing N N 367 
PRO   CA    CB     sing N N 368 
PRO   CA    HA     sing N N 369 
PRO   C     O      doub N N 370 
PRO   C     OXT    sing N N 371 
PRO   CB    CG     sing N N 372 
PRO   CB    HB2    sing N N 373 
PRO   CB    HB3    sing N N 374 
PRO   CG    CD     sing N N 375 
PRO   CG    HG2    sing N N 376 
PRO   CG    HG3    sing N N 377 
PRO   CD    HD2    sing N N 378 
PRO   CD    HD3    sing N N 379 
PRO   OXT   HXT    sing N N 380 
SER   N     CA     sing N N 381 
SER   N     H      sing N N 382 
SER   N     H2     sing N N 383 
SER   CA    C      sing N N 384 
SER   CA    CB     sing N N 385 
SER   CA    HA     sing N N 386 
SER   C     O      doub N N 387 
SER   C     OXT    sing N N 388 
SER   CB    OG     sing N N 389 
SER   CB    HB2    sing N N 390 
SER   CB    HB3    sing N N 391 
SER   OG    HG     sing N N 392 
SER   OXT   HXT    sing N N 393 
THR   N     CA     sing N N 394 
THR   N     H      sing N N 395 
THR   N     H2     sing N N 396 
THR   CA    C      sing N N 397 
THR   CA    CB     sing N N 398 
THR   CA    HA     sing N N 399 
THR   C     O      doub N N 400 
THR   C     OXT    sing N N 401 
THR   CB    OG1    sing N N 402 
THR   CB    CG2    sing N N 403 
THR   CB    HB     sing N N 404 
THR   OG1   HG1    sing N N 405 
THR   CG2   HG21   sing N N 406 
THR   CG2   HG22   sing N N 407 
THR   CG2   HG23   sing N N 408 
THR   OXT   HXT    sing N N 409 
TRP   N     CA     sing N N 410 
TRP   N     H      sing N N 411 
TRP   N     H2     sing N N 412 
TRP   CA    C      sing N N 413 
TRP   CA    CB     sing N N 414 
TRP   CA    HA     sing N N 415 
TRP   C     O      doub N N 416 
TRP   C     OXT    sing N N 417 
TRP   CB    CG     sing N N 418 
TRP   CB    HB2    sing N N 419 
TRP   CB    HB3    sing N N 420 
TRP   CG    CD1    doub Y N 421 
TRP   CG    CD2    sing Y N 422 
TRP   CD1   NE1    sing Y N 423 
TRP   CD1   HD1    sing N N 424 
TRP   CD2   CE2    doub Y N 425 
TRP   CD2   CE3    sing Y N 426 
TRP   NE1   CE2    sing Y N 427 
TRP   NE1   HE1    sing N N 428 
TRP   CE2   CZ2    sing Y N 429 
TRP   CE3   CZ3    doub Y N 430 
TRP   CE3   HE3    sing N N 431 
TRP   CZ2   CH2    doub Y N 432 
TRP   CZ2   HZ2    sing N N 433 
TRP   CZ3   CH2    sing Y N 434 
TRP   CZ3   HZ3    sing N N 435 
TRP   CH2   HH2    sing N N 436 
TRP   OXT   HXT    sing N N 437 
TYR   N     CA     sing N N 438 
TYR   N     H      sing N N 439 
TYR   N     H2     sing N N 440 
TYR   CA    C      sing N N 441 
TYR   CA    CB     sing N N 442 
TYR   CA    HA     sing N N 443 
TYR   C     O      doub N N 444 
TYR   C     OXT    sing N N 445 
TYR   CB    CG     sing N N 446 
TYR   CB    HB2    sing N N 447 
TYR   CB    HB3    sing N N 448 
TYR   CG    CD1    doub Y N 449 
TYR   CG    CD2    sing Y N 450 
TYR   CD1   CE1    sing Y N 451 
TYR   CD1   HD1    sing N N 452 
TYR   CD2   CE2    doub Y N 453 
TYR   CD2   HD2    sing N N 454 
TYR   CE1   CZ     doub Y N 455 
TYR   CE1   HE1    sing N N 456 
TYR   CE2   CZ     sing Y N 457 
TYR   CE2   HE2    sing N N 458 
TYR   CZ    OH     sing N N 459 
TYR   OH    HH     sing N N 460 
TYR   OXT   HXT    sing N N 461 
VAL   N     CA     sing N N 462 
VAL   N     H      sing N N 463 
VAL   N     H2     sing N N 464 
VAL   CA    C      sing N N 465 
VAL   CA    CB     sing N N 466 
VAL   CA    HA     sing N N 467 
VAL   C     O      doub N N 468 
VAL   C     OXT    sing N N 469 
VAL   CB    CG1    sing N N 470 
VAL   CB    CG2    sing N N 471 
VAL   CB    HB     sing N N 472 
VAL   CG1   HG11   sing N N 473 
VAL   CG1   HG12   sing N N 474 
VAL   CG1   HG13   sing N N 475 
VAL   CG2   HG21   sing N N 476 
VAL   CG2   HG22   sing N N 477 
VAL   CG2   HG23   sing N N 478 
VAL   OXT   HXT    sing N N 479 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-12-12 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9MIG 
_em_admin.last_update        2025-03-12 
_em_admin.map_release_date   2025-02-26 
_em_admin.title              'Cryo-EM structure of Human NLRP3 complex with compound 3' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          7108 
_em_entity_assembly_recombinant.organism             'Spodoptera frugiperda' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         43.8 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'FEI FALCON IV (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'        ? 2  ? ? 1 ? ? 
MASKING                    ? 3  ? ? ? ? ? 
'CTF CORRECTION'           ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'       ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'     ? 6  ? ? ? ? ? 
'MODEL FITTING'            ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'         ? 8  ? ? ? ? ? 
OTHER                      ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ? ? 
CLASSIFICATION             ? 12 1 ? ? ? ? 
RECONSTRUCTION             ? 13 1 ? ? ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9MIG 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
F 
H 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N     . LYS   A 1 133  ? 108.081 110.038 99.613  1.00 76.96  ? 133  LYS   C N     1 
ATOM   2    C CA    . LYS   A 1 133  ? 107.525 108.844 100.237 1.00 78.30  ? 133  LYS   C CA    1 
ATOM   3    C C     . LYS   A 1 133  ? 108.625 107.992 100.860 1.00 72.34  ? 133  LYS   C C     1 
ATOM   4    O O     . LYS   A 1 133  ? 109.181 108.346 101.899 1.00 70.34  ? 133  LYS   C O     1 
ATOM   5    C CB    . LYS   A 1 133  ? 106.728 108.031 99.215  1.00 82.44  ? 133  LYS   C CB    1 
ATOM   6    C CG    . LYS   A 1 133  ? 105.444 108.707 98.749  1.00 89.46  ? 133  LYS   C CG    1 
ATOM   7    C CD    . LYS   A 1 133  ? 104.702 107.854 97.726  1.00 92.92  ? 133  LYS   C CD    1 
ATOM   8    C CE    . LYS   A 1 133  ? 103.419 108.533 97.264  1.00 97.84  ? 133  LYS   C CE    1 
ATOM   9    N NZ    . LYS   A 1 133  ? 102.709 107.731 96.232  1.00 102.40 ? 133  LYS   C NZ    1 
ATOM   10   N N     . LYS   A 1 134  ? 108.933 106.864 100.229 1.00 70.76  ? 134  LYS   C N     1 
ATOM   11   C CA    . LYS   A 1 134  ? 109.975 105.980 100.729 1.00 65.23  ? 134  LYS   C CA    1 
ATOM   12   C C     . LYS   A 1 134  ? 111.356 106.544 100.423 1.00 58.68  ? 134  LYS   C C     1 
ATOM   13   O O     . LYS   A 1 134  ? 111.582 107.098 99.346  1.00 60.81  ? 134  LYS   C O     1 
ATOM   14   C CB    . LYS   A 1 134  ? 109.836 104.585 100.119 1.00 66.59  ? 134  LYS   C CB    1 
ATOM   15   C CG    . LYS   A 1 134  ? 108.588 103.826 100.550 1.00 75.74  ? 134  LYS   C CG    1 
ATOM   16   C CD    . LYS   A 1 134  ? 108.545 102.435 99.923  1.00 83.34  ? 134  LYS   C CD    1 
ATOM   17   C CE    . LYS   A 1 134  ? 107.298 101.666 100.346 1.00 88.06  ? 134  LYS   C CE    1 
ATOM   18   N NZ    . LYS   A 1 134  ? 107.238 100.314 99.719  1.00 88.64  ? 134  LYS   C NZ    1 
ATOM   19   N N     . ASP   A 1 135  ? 112.282 106.380 101.361 1.00 51.40  ? 135  ASP   C N     1 
ATOM   20   C CA    . ASP   A 1 135  ? 113.663 106.791 101.152 1.00 42.91  ? 135  ASP   C CA    1 
ATOM   21   C C     . ASP   A 1 135  ? 114.393 105.755 100.309 1.00 38.29  ? 135  ASP   C C     1 
ATOM   22   O O     . ASP   A 1 135  ? 113.979 104.597 100.240 1.00 39.64  ? 135  ASP   C O     1 
ATOM   23   C CB    . ASP   A 1 135  ? 114.377 106.999 102.496 1.00 38.19  ? 135  ASP   C CB    1 
ATOM   24   C CG    . ASP   A 1 135  ? 115.720 107.758 102.387 1.00 36.04  ? 135  ASP   C CG    1 
ATOM   25   O OD1   . ASP   A 1 135  ? 116.237 107.890 101.293 1.00 37.94  ? 135  ASP   C OD1   1 
ATOM   26   O OD2   . ASP   A 1 135  ? 116.213 108.192 103.403 1.00 30.18  ? 135  ASP   C OD2   1 
ATOM   27   N N     . TYR   A 1 136  ? 115.479 106.173 99.677  1.00 32.54  ? 136  TYR   C N     1 
ATOM   28   C CA    . TYR   A 1 136  ? 116.300 105.282 98.871  1.00 27.49  ? 136  TYR   C CA    1 
ATOM   29   C C     . TYR   A 1 136  ? 117.502 104.789 99.657  1.00 24.83  ? 136  TYR   C C     1 
ATOM   30   O O     . TYR   A 1 136  ? 118.020 103.701 99.402  1.00 24.88  ? 136  TYR   C O     1 
ATOM   31   C CB    . TYR   A 1 136  ? 116.759 105.976 97.591  1.00 28.28  ? 136  TYR   C CB    1 
ATOM   32   C CG    . TYR   A 1 136  ? 117.500 105.060 96.642  1.00 23.74  ? 136  TYR   C CG    1 
ATOM   33   C CD1   . TYR   A 1 136  ? 116.800 104.117 95.913  1.00 23.56  ? 136  TYR   C CD1   1 
ATOM   34   C CD2   . TYR   A 1 136  ? 118.871 105.164 96.501  1.00 22.55  ? 136  TYR   C CD2   1 
ATOM   35   C CE1   . TYR   A 1 136  ? 117.466 103.278 95.054  1.00 21.59  ? 136  TYR   C CE1   1 
ATOM   36   C CE2   . TYR   A 1 136  ? 119.539 104.322 95.640  1.00 20.04  ? 136  TYR   C CE2   1 
ATOM   37   C CZ    . TYR   A 1 136  ? 118.837 103.382 94.920  1.00 22.09  ? 136  TYR   C CZ    1 
ATOM   38   O OH    . TYR   A 1 136  ? 119.496 102.539 94.066  1.00 27.38  ? 136  TYR   C OH    1 
ATOM   39   N N     . ARG   A 1 137  ? 117.959 105.596 100.610 1.00 24.25  ? 137  ARG   C N     1 
ATOM   40   C CA    . ARG   A 1 137  ? 119.166 105.263 101.356 1.00 20.39  ? 137  ARG   C CA    1 
ATOM   41   C C     . ARG   A 1 137  ? 119.031 103.924 102.064 1.00 20.40  ? 137  ARG   C C     1 
ATOM   42   O O     . ARG   A 1 137  ? 119.993 103.161 102.148 1.00 20.88  ? 137  ARG   C O     1 
ATOM   43   C CB    . ARG   A 1 137  ? 119.482 106.340 102.378 1.00 20.62  ? 137  ARG   C CB    1 
ATOM   44   C CG    . ARG   A 1 137  ? 120.008 107.626 101.793 1.00 22.65  ? 137  ARG   C CG    1 
ATOM   45   C CD    . ARG   A 1 137  ? 120.270 108.642 102.832 1.00 23.82  ? 137  ARG   C CD    1 
ATOM   46   N NE    . ARG   A 1 137  ? 119.041 109.100 103.447 1.00 26.32  ? 137  ARG   C NE    1 
ATOM   47   C CZ    . ARG   A 1 137  ? 118.944 110.074 104.361 1.00 33.53  ? 137  ARG   C CZ    1 
ATOM   48   N NH1   . ARG   A 1 137  ? 120.012 110.726 104.784 1.00 35.44  ? 137  ARG   C NH1   1 
ATOM   49   N NH2   . ARG   A 1 137  ? 117.750 110.370 104.832 1.00 34.42  ? 137  ARG   C NH2   1 
ATOM   50   N N     . LYS   A 1 138  ? 117.837 103.633 102.568 1.00 23.96  ? 138  LYS   C N     1 
ATOM   51   C CA    . LYS   A 1 138  ? 117.597 102.377 103.262 1.00 20.63  ? 138  LYS   C CA    1 
ATOM   52   C C     . LYS   A 1 138  ? 117.671 101.195 102.306 1.00 21.39  ? 138  LYS   C C     1 
ATOM   53   O O     . LYS   A 1 138  ? 118.136 100.117 102.680 1.00 24.01  ? 138  LYS   C O     1 
ATOM   54   C CB    . LYS   A 1 138  ? 116.243 102.401 103.967 1.00 29.45  ? 138  LYS   C CB    1 
ATOM   55   C CG    . LYS   A 1 138  ? 116.182 103.321 105.181 1.00 35.19  ? 138  LYS   C CG    1 
ATOM   56   C CD    . LYS   A 1 138  ? 114.803 103.282 105.836 1.00 34.57  ? 138  LYS   C CD    1 
ATOM   57   C CE    . LYS   A 1 138  ? 114.735 104.189 107.057 1.00 30.36  ? 138  LYS   C CE    1 
ATOM   58   N NZ    . LYS   A 1 138  ? 113.384 104.167 107.687 1.00 33.81  ? 138  LYS   C NZ    1 
ATOM   59   N N     . LYS   A 1 139  ? 117.199 101.391 101.079 1.00 20.62  ? 139  LYS   C N     1 
ATOM   60   C CA    . LYS   A 1 139  ? 117.198 100.324 100.089 1.00 17.45  ? 139  LYS   C CA    1 
ATOM   61   C C     . LYS   A 1 139  ? 118.618 100.041 99.630  1.00 19.52  ? 139  LYS   C C     1 
ATOM   62   O O     . LYS   A 1 139  ? 119.010 98.885  99.462  1.00 21.97  ? 139  LYS   C O     1 
ATOM   63   C CB    . LYS   A 1 139  ? 116.313 100.694 98.900  1.00 21.73  ? 139  LYS   C CB    1 
ATOM   64   C CG    . LYS   A 1 139  ? 116.110 99.574  97.888  1.00 25.28  ? 139  LYS   C CG    1 
ATOM   65   C CD    . LYS   A 1 139  ? 115.053 99.956  96.853  1.00 28.79  ? 139  LYS   C CD    1 
ATOM   66   C CE    . LYS   A 1 139  ? 114.773 98.811  95.891  1.00 35.16  ? 139  LYS   C CE    1 
ATOM   67   N NZ    . LYS   A 1 139  ? 113.702 99.156  94.911  1.00 45.33  ? 139  LYS   C NZ    1 
ATOM   68   N N     . TYR   A 1 140  ? 119.397 101.102 99.443  1.00 18.91  ? 140  TYR   C N     1 
ATOM   69   C CA    . TYR   A 1 140  ? 120.781 100.946 99.031  1.00 14.25  ? 140  TYR   C CA    1 
ATOM   70   C C     . TYR   A 1 140  ? 121.596 100.261 100.118 1.00 15.10  ? 140  TYR   C C     1 
ATOM   71   O O     . TYR   A 1 140  ? 122.368 99.346  99.834  1.00 19.26  ? 140  TYR   C O     1 
ATOM   72   C CB    . TYR   A 1 140  ? 121.404 102.284 98.653  1.00 13.57  ? 140  TYR   C CB    1 
ATOM   73   C CG    . TYR   A 1 140  ? 122.807 102.132 98.173  1.00 11.14  ? 140  TYR   C CG    1 
ATOM   74   C CD1   . TYR   A 1 140  ? 123.047 101.476 96.987  1.00 16.98  ? 140  TYR   C CD1   1 
ATOM   75   C CD2   . TYR   A 1 140  ? 123.854 102.633 98.905  1.00 11.43  ? 140  TYR   C CD2   1 
ATOM   76   C CE1   . TYR   A 1 140  ? 124.330 101.323 96.537  1.00 15.68  ? 140  TYR   C CE1   1 
ATOM   77   C CE2   . TYR   A 1 140  ? 125.147 102.480 98.446  1.00 11.47  ? 140  TYR   C CE2   1 
ATOM   78   C CZ    . TYR   A 1 140  ? 125.374 101.820 97.261  1.00 11.31  ? 140  TYR   C CZ    1 
ATOM   79   O OH    . TYR   A 1 140  ? 126.645 101.655 96.784  1.00 14.13  ? 140  TYR   C OH    1 
ATOM   80   N N     . ARG   A 1 141  ? 121.426 100.688 101.368 1.00 15.23  ? 141  ARG   C N     1 
ATOM   81   C CA    . ARG   A 1 141  ? 122.156 100.059 102.459 1.00 12.38  ? 141  ARG   C CA    1 
ATOM   82   C C     . ARG   A 1 141  ? 121.829 98.575  102.547 1.00 15.72  ? 141  ARG   C C     1 
ATOM   83   O O     . ARG   A 1 141  ? 122.722 97.757  102.766 1.00 20.74  ? 141  ARG   C O     1 
ATOM   84   C CB    . ARG   A 1 141  ? 121.844 100.727 103.787 1.00 13.26  ? 141  ARG   C CB    1 
ATOM   85   C CG    . ARG   A 1 141  ? 122.485 102.087 103.993 1.00 13.78  ? 141  ARG   C CG    1 
ATOM   86   C CD    . ARG   A 1 141  ? 122.022 102.719 105.252 1.00 13.35  ? 141  ARG   C CD    1 
ATOM   87   N NE    . ARG   A 1 141  ? 122.553 104.063 105.415 1.00 16.34  ? 141  ARG   C NE    1 
ATOM   88   C CZ    . ARG   A 1 141  ? 123.707 104.379 106.044 1.00 16.34  ? 141  ARG   C CZ    1 
ATOM   89   N NH1   . ARG   A 1 141  ? 124.454 103.443 106.585 1.00 16.26  ? 141  ARG   C NH1   1 
ATOM   90   N NH2   . ARG   A 1 141  ? 124.086 105.642 106.116 1.00 16.81  ? 141  ARG   C NH2   1 
ATOM   91   N N     . LYS   A 1 142  ? 120.560 98.217  102.353 1.00 16.54  ? 142  LYS   C N     1 
ATOM   92   C CA    . LYS   A 1 142  ? 120.175 96.813  102.379 1.00 15.66  ? 142  LYS   C CA    1 
ATOM   93   C C     . LYS   A 1 142  ? 120.894 96.039  101.283 1.00 16.55  ? 142  LYS   C C     1 
ATOM   94   O O     . LYS   A 1 142  ? 121.416 94.949  101.522 1.00 20.29  ? 142  LYS   C O     1 
ATOM   95   C CB    . LYS   A 1 142  ? 118.664 96.662  102.229 1.00 20.61  ? 142  LYS   C CB    1 
ATOM   96   C CG    . LYS   A 1 142  ? 118.158 95.225  102.314 1.00 22.56  ? 142  LYS   C CG    1 
ATOM   97   C CD    . LYS   A 1 142  ? 116.635 95.175  102.250 1.00 24.62  ? 142  LYS   C CD    1 
ATOM   98   C CE    . LYS   A 1 142  ? 116.118 93.748  102.310 1.00 25.67  ? 142  LYS   C CE    1 
ATOM   99   N NZ    . LYS   A 1 142  ? 114.632 93.697  102.238 1.00 26.00  ? 142  LYS   C NZ    1 
ATOM   100  N N     . TYR   A 1 143  ? 120.940 96.612  100.086 1.00 16.25  ? 143  TYR   C N     1 
ATOM   101  C CA    . TYR   A 1 143  ? 121.632 95.990  98.966  1.00 16.89  ? 143  TYR   C CA    1 
ATOM   102  C C     . TYR   A 1 143  ? 123.098 95.736  99.284  1.00 18.42  ? 143  TYR   C C     1 
ATOM   103  O O     . TYR   A 1 143  ? 123.612 94.640  99.045  1.00 20.50  ? 143  TYR   C O     1 
ATOM   104  C CB    . TYR   A 1 143  ? 121.498 96.857  97.719  1.00 20.05  ? 143  TYR   C CB    1 
ATOM   105  C CG    . TYR   A 1 143  ? 122.281 96.369  96.544  1.00 18.57  ? 143  TYR   C CG    1 
ATOM   106  C CD1   . TYR   A 1 143  ? 121.880 95.236  95.874  1.00 21.59  ? 143  TYR   C CD1   1 
ATOM   107  C CD2   . TYR   A 1 143  ? 123.389 97.074  96.117  1.00 23.64  ? 143  TYR   C CD2   1 
ATOM   108  C CE1   . TYR   A 1 143  ? 122.588 94.798  94.779  1.00 26.65  ? 143  TYR   C CE1   1 
ATOM   109  C CE2   . TYR   A 1 143  ? 124.099 96.639  95.022  1.00 28.30  ? 143  TYR   C CE2   1 
ATOM   110  C CZ    . TYR   A 1 143  ? 123.698 95.507  94.351  1.00 30.47  ? 143  TYR   C CZ    1 
ATOM   111  O OH    . TYR   A 1 143  ? 124.397 95.075  93.249  1.00 36.40  ? 143  TYR   C OH    1 
ATOM   112  N N     . VAL   A 1 144  ? 123.775 96.742  99.827  1.00 16.05  ? 144  VAL   C N     1 
ATOM   113  C CA    . VAL   A 1 144  ? 125.185 96.601  100.153 1.00 11.92  ? 144  VAL   C CA    1 
ATOM   114  C C     . VAL   A 1 144  ? 125.401 95.522  101.205 1.00 14.33  ? 144  VAL   C C     1 
ATOM   115  O O     . VAL   A 1 144  ? 126.319 94.712  101.079 1.00 19.76  ? 144  VAL   C O     1 
ATOM   116  C CB    . VAL   A 1 144  ? 125.770 97.932  100.644 1.00 9.65   ? 144  VAL   C CB    1 
ATOM   117  C CG1   . VAL   A 1 144  ? 127.187 97.726  101.168 1.00 11.76  ? 144  VAL   C CG1   1 
ATOM   118  C CG2   . VAL   A 1 144  ? 125.777 98.926  99.504  1.00 14.01  ? 144  VAL   C CG2   1 
ATOM   119  N N     . ARG   A 1 145  ? 124.563 95.494  102.241 1.00 15.52  ? 145  ARG   C N     1 
ATOM   120  C CA    . ARG   A 1 145  ? 124.714 94.467  103.264 1.00 12.98  ? 145  ARG   C CA    1 
ATOM   121  C C     . ARG   A 1 145  ? 124.557 93.078  102.669 1.00 16.70  ? 145  ARG   C C     1 
ATOM   122  O O     . ARG   A 1 145  ? 125.311 92.167  103.002 1.00 21.32  ? 145  ARG   C O     1 
ATOM   123  C CB    . ARG   A 1 145  ? 123.683 94.602  104.378 1.00 14.01  ? 145  ARG   C CB    1 
ATOM   124  C CG    . ARG   A 1 145  ? 123.869 95.759  105.323 1.00 14.18  ? 145  ARG   C CG    1 
ATOM   125  C CD    . ARG   A 1 145  ? 123.071 95.591  106.562 1.00 15.49  ? 145  ARG   C CD    1 
ATOM   126  N NE    . ARG   A 1 145  ? 121.643 95.539  106.306 1.00 14.67  ? 145  ARG   C NE    1 
ATOM   127  C CZ    . ARG   A 1 145  ? 120.816 96.608  106.262 1.00 17.05  ? 145  ARG   C CZ    1 
ATOM   128  N NH1   . ARG   A 1 145  ? 121.271 97.830  106.455 1.00 19.35  ? 145  ARG   C NH1   1 
ATOM   129  N NH2   . ARG   A 1 145  ? 119.530 96.425  106.026 1.00 19.68  ? 145  ARG   C NH2   1 
ATOM   130  N N     . SER   A 1 146  ? 123.577 92.908  101.789 1.00 16.89  ? 146  SER   C N     1 
ATOM   131  C CA    . SER   A 1 146  ? 123.322 91.600  101.203 1.00 16.96  ? 146  SER   C CA    1 
ATOM   132  C C     . SER   A 1 146  ? 124.424 91.152  100.255 1.00 21.48  ? 146  SER   C C     1 
ATOM   133  O O     . SER   A 1 146  ? 124.782 89.974  100.227 1.00 27.62  ? 146  SER   C O     1 
ATOM   134  C CB    . SER   A 1 146  ? 122.002 91.608  100.459 1.00 17.33  ? 146  SER   C CB    1 
ATOM   135  O OG    . SER   A 1 146  ? 120.923 91.738  101.343 1.00 20.65  ? 146  SER   C OG    1 
ATOM   136  N N     . ARG   A 1 147  ? 124.950 92.079  99.462  1.00 19.97  ? 147  ARG   C N     1 
ATOM   137  C CA    . ARG   A 1 147  ? 125.959 91.729  98.473  1.00 18.97  ? 147  ARG   C CA    1 
ATOM   138  C C     . ARG   A 1 147  ? 127.342 91.481  99.070  1.00 21.63  ? 147  ARG   C C     1 
ATOM   139  O O     . ARG   A 1 147  ? 127.980 90.473  98.767  1.00 27.10  ? 147  ARG   C O     1 
ATOM   140  C CB    . ARG   A 1 147  ? 126.057 92.810  97.410  1.00 21.37  ? 147  ARG   C CB    1 
ATOM   141  C CG    . ARG   A 1 147  ? 127.045 92.512  96.304  1.00 26.76  ? 147  ARG   C CG    1 
ATOM   142  C CD    . ARG   A 1 147  ? 126.906 93.449  95.170  1.00 28.63  ? 147  ARG   C CD    1 
ATOM   143  N NE    . ARG   A 1 147  ? 127.810 93.099  94.084  1.00 37.79  ? 147  ARG   C NE    1 
ATOM   144  C CZ    . ARG   A 1 147  ? 129.049 93.595  93.901  1.00 41.17  ? 147  ARG   C CZ    1 
ATOM   145  N NH1   . ARG   A 1 147  ? 129.546 94.491  94.722  1.00 36.14  ? 147  ARG   C NH1   1 
ATOM   146  N NH2   . ARG   A 1 147  ? 129.763 93.166  92.879  1.00 50.07  ? 147  ARG   C NH2   1 
ATOM   147  N N     . PHE   A 1 148  ? 127.816 92.391  99.913  1.00 19.67  ? 148  PHE   C N     1 
ATOM   148  C CA    . PHE   A 1 148  ? 129.180 92.293  100.430 1.00 18.31  ? 148  PHE   C CA    1 
ATOM   149  C C     . PHE   A 1 148  ? 129.276 91.407  101.665 1.00 22.30  ? 148  PHE   C C     1 
ATOM   150  O O     . PHE   A 1 148  ? 129.558 91.886  102.759 1.00 23.20  ? 148  PHE   C O     1 
ATOM   151  C CB    . PHE   A 1 148  ? 129.714 93.686  100.762 1.00 14.12  ? 148  PHE   C CB    1 
ATOM   152  C CG    . PHE   A 1 148  ? 129.958 94.556  99.561  1.00 13.89  ? 148  PHE   C CG    1 
ATOM   153  C CD1   . PHE   A 1 148  ? 128.944 95.309  99.023  1.00 16.41  ? 148  PHE   C CD1   1 
ATOM   154  C CD2   . PHE   A 1 148  ? 131.206 94.632  98.986  1.00 14.44  ? 148  PHE   C CD2   1 
ATOM   155  C CE1   . PHE   A 1 148  ? 129.162 96.122  97.939  1.00 15.70  ? 148  PHE   C CE1   1 
ATOM   156  C CE2   . PHE   A 1 148  ? 131.432 95.445  97.898  1.00 12.28  ? 148  PHE   C CE2   1 
ATOM   157  C CZ    . PHE   A 1 148  ? 130.406 96.191  97.377  1.00 12.20  ? 148  PHE   C CZ    1 
ATOM   158  N N     . GLN   A 1 149  ? 129.052 90.110  101.478 1.00 27.89  ? 149  GLN   C N     1 
ATOM   159  C CA    . GLN   A 1 149  ? 129.098 89.144  102.578 1.00 30.53  ? 149  GLN   C CA    1 
ATOM   160  C C     . GLN   A 1 149  ? 130.274 88.176  102.533 1.00 40.30  ? 149  GLN   C C     1 
ATOM   161  O O     . GLN   A 1 149  ? 130.566 87.514  103.532 1.00 43.22  ? 149  GLN   C O     1 
ATOM   162  C CB    . GLN   A 1 149  ? 127.802 88.341  102.642 1.00 30.68  ? 149  GLN   C CB    1 
ATOM   163  C CG    . GLN   A 1 149  ? 126.615 89.127  103.114 1.00 27.68  ? 149  GLN   C CG    1 
ATOM   164  C CD    . GLN   A 1 149  ? 126.747 89.496  104.585 1.00 31.07  ? 149  GLN   C CD    1 
ATOM   165  O OE1   . GLN   A 1 149  ? 127.069 88.641  105.417 1.00 36.18  ? 149  GLN   C OE1   1 
ATOM   166  N NE2   . GLN   A 1 149  ? 126.501 90.748  104.914 1.00 24.59  ? 149  GLN   C NE2   1 
ATOM   167  N N     . CYS   A 1 150  ? 130.923 88.048  101.381 1.00 41.64  ? 150  CYS   C N     1 
ATOM   168  C CA    . CYS   A 1 150  ? 131.977 87.058  101.238 1.00 48.72  ? 150  CYS   C CA    1 
ATOM   169  C C     . CYS   A 1 150  ? 133.337 87.705  101.024 1.00 49.91  ? 150  CYS   C C     1 
ATOM   170  O O     . CYS   A 1 150  ? 133.434 88.854  100.597 1.00 46.34  ? 150  CYS   C O     1 
ATOM   171  C CB    . CYS   A 1 150  ? 131.665 86.134  100.070 1.00 50.21  ? 150  CYS   C CB    1 
ATOM   172  S SG    . CYS   A 1 150  ? 130.107 85.259  100.228 1.00 57.60  ? 150  CYS   C SG    1 
ATOM   173  N N     . ILE   A 1 151  ? 134.393 86.954  101.317 1.00 49.92  ? 151  ILE   C N     1 
ATOM   174  C CA    . ILE   A 1 151  ? 135.750 87.427  101.081 1.00 49.43  ? 151  ILE   C CA    1 
ATOM   175  C C     . ILE   A 1 151  ? 136.043 87.499  99.586  1.00 50.98  ? 151  ILE   C C     1 
ATOM   176  O O     . ILE   A 1 151  ? 136.620 88.473  99.107  1.00 46.56  ? 151  ILE   C O     1 
ATOM   177  C CB    . ILE   A 1 151  ? 136.775 86.528  101.801 1.00 47.37  ? 151  ILE   C CB    1 
ATOM   178  C CG1   . ILE   A 1 151  ? 136.612 86.710  103.320 1.00 46.94  ? 151  ILE   C CG1   1 
ATOM   179  C CG2   . ILE   A 1 151  ? 138.191 86.851  101.362 1.00 35.69  ? 151  ILE   C CG2   1 
ATOM   180  C CD1   . ILE   A 1 151  ? 137.378 85.720  104.160 1.00 43.66  ? 151  ILE   C CD1   1 
ATOM   181  N N     . GLU   A 1 152  ? 135.652 86.459  98.854  1.00 54.25  ? 152  GLU   C N     1 
ATOM   182  C CA    . GLU   A 1 152  ? 135.873 86.405  97.413  1.00 56.83  ? 152  GLU   C CA    1 
ATOM   183  C C     . GLU   A 1 152  ? 134.724 87.017  96.613  1.00 56.24  ? 152  GLU   C C     1 
ATOM   184  O O     . GLU   A 1 152  ? 134.937 87.579  95.538  1.00 57.61  ? 152  GLU   C O     1 
ATOM   185  C CB    . GLU   A 1 152  ? 136.073 84.951  96.967  1.00 62.43  ? 152  GLU   C CB    1 
ATOM   186  C CG    . GLU   A 1 152  ? 137.359 84.307  97.454  1.00 58.04  ? 152  GLU   C CG    1 
ATOM   187  C CD    . GLU   A 1 152  ? 138.567 84.871  96.765  1.00 55.06  ? 152  GLU   C CD    1 
ATOM   188  O OE1   . GLU   A 1 152  ? 138.484 85.126  95.586  1.00 55.32  ? 152  GLU   C OE1   1 
ATOM   189  O OE2   . GLU   A 1 152  ? 139.580 85.036  97.405  1.00 44.08  ? 152  GLU   C OE2   1 
ATOM   190  N N     . ASP   A 1 153  ? 133.500 86.851  97.118  1.00 55.55  ? 153  ASP   C N     1 
ATOM   191  C CA    . ASP   A 1 153  ? 132.280 87.234  96.403  1.00 58.99  ? 153  ASP   C CA    1 
ATOM   192  C C     . ASP   A 1 153  ? 132.260 86.615  95.010  1.00 64.27  ? 153  ASP   C C     1 
ATOM   193  O O     . ASP   A 1 153  ? 131.836 87.243  94.036  1.00 65.93  ? 153  ASP   C O     1 
ATOM   194  C CB    . ASP   A 1 153  ? 132.124 88.761  96.326  1.00 56.78  ? 153  ASP   C CB    1 
ATOM   195  C CG    . ASP   A 1 153  ? 131.819 89.417  97.694  1.00 48.67  ? 153  ASP   C CG    1 
ATOM   196  O OD1   . ASP   A 1 153  ? 131.119 88.812  98.493  1.00 46.86  ? 153  ASP   C OD1   1 
ATOM   197  O OD2   . ASP   A 1 153  ? 132.269 90.519  97.910  1.00 37.32  ? 153  ASP   C OD2   1 
ATOM   198  N N     . ARG   A 1 154  ? 132.721 85.371  94.930  1.00 66.45  ? 154  ARG   C N     1 
ATOM   199  C CA    . ARG   A 1 154  ? 132.787 84.623  93.684  1.00 68.07  ? 154  ARG   C CA    1 
ATOM   200  C C     . ARG   A 1 154  ? 132.570 83.138  93.919  1.00 71.22  ? 154  ARG   C C     1 
ATOM   201  O O     . ARG   A 1 154  ? 132.648 82.652  95.047  1.00 68.21  ? 154  ARG   C O     1 
ATOM   202  C CB    . ARG   A 1 154  ? 134.119 84.829  92.974  1.00 67.24  ? 154  ARG   C CB    1 
ATOM   203  C CG    . ARG   A 1 154  ? 134.140 85.965  91.947  1.00 67.22  ? 154  ARG   C CG    1 
ATOM   204  C CD    . ARG   A 1 154  ? 134.723 87.216  92.478  1.00 63.88  ? 154  ARG   C CD    1 
ATOM   205  N NE    . ARG   A 1 154  ? 134.849 88.223  91.440  1.00 67.20  ? 154  ARG   C NE    1 
ATOM   206  C CZ    . ARG   A 1 154  ? 133.939 89.188  91.180  1.00 64.39  ? 154  ARG   C CZ    1 
ATOM   207  N NH1   . ARG   A 1 154  ? 132.829 89.274  91.892  1.00 64.69  ? 154  ARG   C NH1   1 
ATOM   208  N NH2   . ARG   A 1 154  ? 134.165 90.045  90.202  1.00 61.16  ? 154  ARG   C NH2   1 
ATOM   209  N N     . ASN   A 1 155  ? 132.290 82.418  92.841  1.00 73.63  ? 155  ASN   C N     1 
ATOM   210  C CA    . ASN   A 1 155  ? 132.120 80.976  92.894  1.00 74.53  ? 155  ASN   C CA    1 
ATOM   211  C C     . ASN   A 1 155  ? 133.483 80.297  92.859  1.00 81.06  ? 155  ASN   C C     1 
ATOM   212  O O     . ASN   A 1 155  ? 134.507 80.931  93.103  1.00 67.27  ? 155  ASN   C O     1 
ATOM   213  C CB    . ASN   A 1 155  ? 131.265 80.481  91.746  1.00 78.10  ? 155  ASN   C CB    1 
ATOM   214  C CG    . ASN   A 1 155  ? 131.980 80.506  90.420  1.00 73.41  ? 155  ASN   C CG    1 
ATOM   215  O OD1   . ASN   A 1 155  ? 132.935 81.276  90.213  1.00 69.15  ? 155  ASN   C OD1   1 
ATOM   216  N ND2   . ASN   A 1 155  ? 131.545 79.657  89.523  1.00 73.36  ? 155  ASN   C ND2   1 
ATOM   217  N N     . ALA   A 1 156  ? 133.476 78.995  92.587  1.00 81.20  ? 156  ALA   C N     1 
ATOM   218  C CA    . ALA   A 1 156  ? 134.673 78.162  92.499  1.00 75.36  ? 156  ALA   C CA    1 
ATOM   219  C C     . ALA   A 1 156  ? 135.385 77.973  93.837  1.00 83.75  ? 156  ALA   C C     1 
ATOM   220  O O     . ALA   A 1 156  ? 136.483 77.426  93.877  1.00 77.92  ? 156  ALA   C O     1 
ATOM   221  C CB    . ALA   A 1 156  ? 135.647 78.762  91.487  1.00 67.14  ? 156  ALA   C CB    1 
ATOM   222  N N     . ARG   A 1 157  ? 134.754 78.347  94.946  1.00 87.22  ? 157  ARG   C N     1 
ATOM   223  C CA    . ARG   A 1 157  ? 135.404 78.152  96.238  1.00 90.36  ? 157  ARG   C CA    1 
ATOM   224  C C     . ARG   A 1 157  ? 135.258 76.717  96.732  1.00 93.49  ? 157  ARG   C C     1 
ATOM   225  O O     . ARG   A 1 157  ? 134.524 76.441  97.681  1.00 98.02  ? 157  ARG   C O     1 
ATOM   226  C CB    . ARG   A 1 157  ? 134.857 79.110  97.287  1.00 81.31  ? 157  ARG   C CB    1 
ATOM   227  C CG    . ARG   A 1 157  ? 135.613 79.079  98.621  1.00 90.09  ? 157  ARG   C CG    1 
ATOM   228  C CD    . ARG   A 1 157  ? 135.143 80.123  99.561  1.00 84.75  ? 157  ARG   C CD    1 
ATOM   229  N NE    . ARG   A 1 157  ? 135.821 80.027  100.851 1.00 81.65  ? 157  ARG   C NE    1 
ATOM   230  C CZ    . ARG   A 1 157  ? 137.011 80.596  101.150 1.00 78.94  ? 157  ARG   C CZ    1 
ATOM   231  N NH1   . ARG   A 1 157  ? 137.656 81.307  100.249 1.00 76.00  ? 157  ARG   C NH1   1 
ATOM   232  N NH2   . ARG   A 1 157  ? 137.530 80.436  102.357 1.00 81.89  ? 157  ARG   C NH2   1 
ATOM   233  N N     . LEU   A 1 158  ? 135.964 75.807  96.066  1.00 86.67  ? 158  LEU   C N     1 
ATOM   234  C CA    . LEU   A 1 158  ? 136.001 74.392  96.427  1.00 96.14  ? 158  LEU   C CA    1 
ATOM   235  C C     . LEU   A 1 158  ? 134.623 73.851  96.794  1.00 93.72  ? 158  LEU   C C     1 
ATOM   236  O O     . LEU   A 1 158  ? 134.390 73.440  97.931  1.00 96.03  ? 158  LEU   C O     1 
ATOM   237  C CB    . LEU   A 1 158  ? 136.970 74.183  97.599  1.00 91.44  ? 158  LEU   C CB    1 
ATOM   238  C CG    . LEU   A 1 158  ? 138.429 74.658  97.362  1.00 89.95  ? 158  LEU   C CG    1 
ATOM   239  C CD1   . LEU   A 1 158  ? 139.221 74.498  98.647  1.00 78.10  ? 158  LEU   C CD1   1 
ATOM   240  C CD2   . LEU   A 1 158  ? 139.070 73.847  96.228  1.00 73.96  ? 158  LEU   C CD2   1 
ATOM   241  N N     . GLY   A 1 159  ? 133.704 73.863  95.831  1.00 95.62  ? 159  GLY   C N     1 
ATOM   242  C CA    . GLY   A 1 159  ? 132.328 73.443  96.085  1.00 102.68 ? 159  GLY   C CA    1 
ATOM   243  C C     . GLY   A 1 159  ? 131.406 74.648  96.232  1.00 90.26  ? 159  GLY   C C     1 
ATOM   244  O O     . GLY   A 1 159  ? 130.252 74.516  96.642  1.00 101.79 ? 159  GLY   C O     1 
ATOM   245  N N     . GLU   A 1 160  ? 131.930 75.819  95.882  1.00 96.37  ? 160  GLU   C N     1 
ATOM   246  C CA    . GLU   A 1 160  ? 131.196 77.081  95.934  1.00 85.74  ? 160  GLU   C CA    1 
ATOM   247  C C     . GLU   A 1 160  ? 130.632 77.376  97.319  1.00 204.45 ? 160  GLU   C C     1 
ATOM   248  O O     . GLU   A 1 160  ? 129.476 77.780  97.456  1.00 104.07 ? 160  GLU   C O     1 
ATOM   249  C CB    . GLU   A 1 160  ? 130.065 77.084  94.898  1.00 94.35  ? 160  GLU   C CB    1 
ATOM   250  C CG    . GLU   A 1 160  ? 130.544 76.907  93.463  1.00 94.09  ? 160  GLU   C CG    1 
ATOM   251  C CD    . GLU   A 1 160  ? 129.468 77.100  92.424  1.00 89.35  ? 160  GLU   C CD    1 
ATOM   252  O OE1   . GLU   A 1 160  ? 128.332 77.296  92.786  1.00 112.98 ? 160  GLU   C OE1   1 
ATOM   253  O OE2   . GLU   A 1 160  ? 129.794 77.055  91.260  1.00 97.58  ? 160  GLU   C OE2   1 
ATOM   254  N N     . SER   A 1 161  ? 131.459 77.193  98.343  1.00 99.76  ? 161  SER   C N     1 
ATOM   255  C CA    . SER   A 1 161  ? 131.054 77.481  99.710  1.00 90.21  ? 161  SER   C CA    1 
ATOM   256  C C     . SER   A 1 161  ? 131.105 78.977  99.991  1.00 87.33  ? 161  SER   C C     1 
ATOM   257  O O     . SER   A 1 161  ? 131.616 79.760  99.188  1.00 95.38  ? 161  SER   C O     1 
ATOM   258  C CB    . SER   A 1 161  ? 131.935 76.736  100.694 1.00 91.60  ? 161  SER   C CB    1 
ATOM   259  O OG    . SER   A 1 161  ? 133.238 77.246  100.692 1.00 91.60  ? 161  SER   C OG    1 
ATOM   260  N N     . VAL   A 1 162  ? 130.563 79.370  101.137 1.00 92.82  ? 162  VAL   C N     1 
ATOM   261  C CA    . VAL   A 1 162  ? 130.571 80.766  101.550 1.00 81.91  ? 162  VAL   C CA    1 
ATOM   262  C C     . VAL   A 1 162  ? 131.737 81.028  102.497 1.00 78.42  ? 162  VAL   C C     1 
ATOM   263  O O     . VAL   A 1 162  ? 131.848 80.388  103.542 1.00 76.15  ? 162  VAL   C O     1 
ATOM   264  C CB    . VAL   A 1 162  ? 129.235 81.119  102.237 1.00 82.15  ? 162  VAL   C CB    1 
ATOM   265  C CG1   . VAL   A 1 162  ? 129.243 82.550  102.705 1.00 75.78  ? 162  VAL   C CG1   1 
ATOM   266  C CG2   . VAL   A 1 162  ? 128.091 80.904  101.260 1.00 85.31  ? 162  VAL   C CG2   1 
ATOM   267  N N     . SER   A 1 163  ? 132.610 81.958  102.120 1.00 72.63  ? 163  SER   C N     1 
ATOM   268  C CA    . SER   A 1 163  ? 133.804 82.265  102.902 1.00 72.32  ? 163  SER   C CA    1 
ATOM   269  C C     . SER   A 1 163  ? 133.472 82.967  104.209 1.00 64.75  ? 163  SER   C C     1 
ATOM   270  O O     . SER   A 1 163  ? 134.148 82.761  105.221 1.00 64.84  ? 163  SER   C O     1 
ATOM   271  C CB    . SER   A 1 163  ? 134.716 83.157  102.092 1.00 67.10  ? 163  SER   C CB    1 
ATOM   272  O OG    . SER   A 1 163  ? 134.104 84.393  101.851 1.00 58.76  ? 163  SER   C OG    1 
ATOM   273  N N     . LEU   A 1 164  ? 132.421 83.784  104.173 1.00 63.29  ? 164  LEU   C N     1 
ATOM   274  C CA    . LEU   A 1 164  ? 131.937 84.566  105.306 1.00 60.31  ? 164  LEU   C CA    1 
ATOM   275  C C     . LEU   A 1 164  ? 132.942 85.630  105.736 1.00 55.91  ? 164  LEU   C C     1 
ATOM   276  O O     . LEU   A 1 164  ? 134.031 85.314  106.215 1.00 52.39  ? 164  LEU   C O     1 
ATOM   277  C CB    . LEU   A 1 164  ? 131.616 83.648  106.499 1.00 60.74  ? 164  LEU   C CB    1 
ATOM   278  C CG    . LEU   A 1 164  ? 130.528 82.587  106.268 1.00 61.82  ? 164  LEU   C CG    1 
ATOM   279  C CD1   . LEU   A 1 164  ? 130.494 81.650  107.443 1.00 64.24  ? 164  LEU   C CD1   1 
ATOM   280  C CD2   . LEU   A 1 164  ? 129.176 83.267  106.097 1.00 60.72  ? 164  LEU   C CD2   1 
ATOM   281  N N     . ASN   A 1 165  ? 132.551 86.899  105.637 1.00 51.38  ? 165  ASN   C N     1 
ATOM   282  C CA    . ASN   A 1 165  ? 133.432 87.997  106.028 1.00 50.53  ? 165  ASN   C CA    1 
ATOM   283  C C     . ASN   A 1 165  ? 133.731 88.028  107.523 1.00 52.07  ? 165  ASN   C C     1 
ATOM   284  O O     . ASN   A 1 165  ? 134.597 88.781  107.966 1.00 48.47  ? 165  ASN   C O     1 
ATOM   285  C CB    . ASN   A 1 165  ? 132.882 89.337  105.574 1.00 45.19  ? 165  ASN   C CB    1 
ATOM   286  C CG    . ASN   A 1 165  ? 133.176 89.606  104.131 1.00 43.34  ? 165  ASN   C CG    1 
ATOM   287  O OD1   . ASN   A 1 165  ? 134.151 89.079  103.590 1.00 45.65  ? 165  ASN   C OD1   1 
ATOM   288  N ND2   . ASN   A 1 165  ? 132.370 90.410  103.497 1.00 41.25  ? 165  ASN   C ND2   1 
ATOM   289  N N     . LYS   A 1 166  ? 133.052 87.189  108.302 1.00 53.14  ? 166  LYS   C N     1 
ATOM   290  C CA    . LYS   A 1 166  ? 133.330 87.106  109.733 1.00 55.86  ? 166  LYS   C CA    1 
ATOM   291  C C     . LYS   A 1 166  ? 134.725 86.525  109.949 1.00 52.19  ? 166  LYS   C C     1 
ATOM   292  O O     . LYS   A 1 166  ? 135.295 86.627  111.033 1.00 52.67  ? 166  LYS   C O     1 
ATOM   293  C CB    . LYS   A 1 166  ? 132.300 86.241  110.466 1.00 57.00  ? 166  LYS   C CB    1 
ATOM   294  C CG    . LYS   A 1 166  ? 132.464 84.732  110.267 1.00 58.83  ? 166  LYS   C CG    1 
ATOM   295  C CD    . LYS   A 1 166  ? 131.362 83.958  110.986 1.00 62.30  ? 166  LYS   C CD    1 
ATOM   296  C CE    . LYS   A 1 166  ? 131.641 82.456  110.993 1.00 64.17  ? 166  LYS   C CE    1 
ATOM   297  N NZ    . LYS   A 1 166  ? 130.532 81.689  111.632 1.00 66.72  ? 166  LYS   C NZ    1 
ATOM   298  N N     . ARG   A 1 167  ? 135.256 85.898  108.900 1.00 51.49  ? 167  ARG   C N     1 
ATOM   299  C CA    . ARG   A 1 167  ? 136.571 85.275  108.901 1.00 51.28  ? 167  ARG   C CA    1 
ATOM   300  C C     . ARG   A 1 167  ? 137.684 86.305  108.722 1.00 44.25  ? 167  ARG   C C     1 
ATOM   301  O O     . ARG   A 1 167  ? 138.867 85.988  108.860 1.00 38.61  ? 167  ARG   C O     1 
ATOM   302  C CB    . ARG   A 1 167  ? 136.636 84.246  107.782 1.00 55.36  ? 167  ARG   C CB    1 
ATOM   303  C CG    . ARG   A 1 167  ? 137.909 83.422  107.693 1.00 49.17  ? 167  ARG   C CG    1 
ATOM   304  C CD    . ARG   A 1 167  ? 137.843 82.463  106.557 1.00 50.49  ? 167  ARG   C CD    1 
ATOM   305  N NE    . ARG   A 1 167  ? 136.692 81.574  106.663 1.00 71.30  ? 167  ARG   C NE    1 
ATOM   306  C CZ    . ARG   A 1 167  ? 136.637 80.483  107.457 1.00 77.36  ? 167  ARG   C CZ    1 
ATOM   307  N NH1   . ARG   A 1 167  ? 137.670 80.163  108.205 1.00 67.49  ? 167  ARG   C NH1   1 
ATOM   308  N NH2   . ARG   A 1 167  ? 135.541 79.741  107.488 1.00 75.76  ? 167  ARG   C NH2   1 
ATOM   309  N N     . TYR   A 1 168  ? 137.307 87.536  108.394 1.00 40.81  ? 168  TYR   C N     1 
ATOM   310  C CA    . TYR   A 1 168  ? 138.278 88.590  108.148 1.00 35.11  ? 168  TYR   C CA    1 
ATOM   311  C C     . TYR   A 1 168  ? 139.164 88.855  109.353 1.00 34.57  ? 168  TYR   C C     1 
ATOM   312  O O     . TYR   A 1 168  ? 138.682 89.072  110.465 1.00 36.42  ? 168  TYR   C O     1 
ATOM   313  C CB    . TYR   A 1 168  ? 137.554 89.879  107.761 1.00 32.45  ? 168  TYR   C CB    1 
ATOM   314  C CG    . TYR   A 1 168  ? 138.445 91.097  107.695 1.00 28.68  ? 168  TYR   C CG    1 
ATOM   315  C CD1   . TYR   A 1 168  ? 139.273 91.299  106.619 1.00 28.09  ? 168  TYR   C CD1   1 
ATOM   316  C CD2   . TYR   A 1 168  ? 138.421 92.015  108.729 1.00 30.00  ? 168  TYR   C CD2   1 
ATOM   317  C CE1   . TYR   A 1 168  ? 140.079 92.418  106.567 1.00 24.91  ? 168  TYR   C CE1   1 
ATOM   318  C CE2   . TYR   A 1 168  ? 139.220 93.129  108.681 1.00 27.92  ? 168  TYR   C CE2   1 
ATOM   319  C CZ    . TYR   A 1 168  ? 140.047 93.332  107.608 1.00 26.24  ? 168  TYR   C CZ    1 
ATOM   320  O OH    . TYR   A 1 168  ? 140.849 94.445  107.565 1.00 27.54  ? 168  TYR   C OH    1 
ATOM   321  N N     . THR   A 1 169  ? 140.466 88.895  109.107 1.00 31.48  ? 169  THR   C N     1 
ATOM   322  C CA    . THR   A 1 169  ? 141.439 89.224  110.134 1.00 30.47  ? 169  THR   C CA    1 
ATOM   323  C C     . THR   A 1 169  ? 141.909 90.659  109.946 1.00 30.22  ? 169  THR   C C     1 
ATOM   324  O O     . THR   A 1 169  ? 142.310 91.057  108.852 1.00 28.05  ? 169  THR   C O     1 
ATOM   325  C CB    . THR   A 1 169  ? 142.630 88.252  110.088 1.00 28.64  ? 169  THR   C CB    1 
ATOM   326  O OG1   . THR   A 1 169  ? 142.167 86.921  110.348 1.00 29.18  ? 169  THR   C OG1   1 
ATOM   327  C CG2   . THR   A 1 169  ? 143.676 88.630  111.119 1.00 26.91  ? 169  THR   C CG2   1 
ATOM   328  N N     . ARG   A 1 170  ? 141.836 91.445  111.010 1.00 33.52  ? 170  ARG   C N     1 
ATOM   329  C CA    . ARG   A 1 170  ? 142.179 92.859  110.932 1.00 32.98  ? 170  ARG   C CA    1 
ATOM   330  C C     . ARG   A 1 170  ? 143.619 93.077  110.493 1.00 32.49  ? 170  ARG   C C     1 
ATOM   331  O O     . ARG   A 1 170  ? 144.535 92.418  110.985 1.00 29.95  ? 170  ARG   C O     1 
ATOM   332  C CB    . ARG   A 1 170  ? 141.961 93.535  112.278 1.00 36.62  ? 170  ARG   C CB    1 
ATOM   333  C CG    . ARG   A 1 170  ? 142.154 95.048  112.281 1.00 38.91  ? 170  ARG   C CG    1 
ATOM   334  C CD    . ARG   A 1 170  ? 141.958 95.624  113.638 1.00 48.77  ? 170  ARG   C CD    1 
ATOM   335  N NE    . ARG   A 1 170  ? 140.580 95.492  114.100 1.00 49.96  ? 170  ARG   C NE    1 
ATOM   336  C CZ    . ARG   A 1 170  ? 139.581 96.358  113.819 1.00 48.43  ? 170  ARG   C CZ    1 
ATOM   337  N NH1   . ARG   A 1 170  ? 139.807 97.421  113.076 1.00 45.30  ? 170  ARG   C NH1   1 
ATOM   338  N NH2   . ARG   A 1 170  ? 138.369 96.135  114.296 1.00 42.22  ? 170  ARG   C NH2   1 
ATOM   339  N N     . LEU   A 1 171  ? 143.810 94.016  109.572 1.00 28.67  ? 171  LEU   C N     1 
ATOM   340  C CA    . LEU   A 1 171  ? 145.139 94.400  109.121 1.00 21.02  ? 171  LEU   C CA    1 
ATOM   341  C C     . LEU   A 1 171  ? 145.475 95.757  109.715 1.00 19.54  ? 171  LEU   C C     1 
ATOM   342  O O     . LEU   A 1 171  ? 144.595 96.603  109.870 1.00 22.66  ? 171  LEU   C O     1 
ATOM   343  C CB    . LEU   A 1 171  ? 145.191 94.466  107.588 1.00 16.09  ? 171  LEU   C CB    1 
ATOM   344  C CG    . LEU   A 1 171  ? 144.780 93.183  106.834 1.00 16.21  ? 171  LEU   C CG    1 
ATOM   345  C CD1   . LEU   A 1 171  ? 144.815 93.452  105.336 1.00 14.39  ? 171  LEU   C CD1   1 
ATOM   346  C CD2   . LEU   A 1 171  ? 145.723 92.048  107.193 1.00 15.47  ? 171  LEU   C CD2   1 
ATOM   347  N N     . ARG   A 1 172  ? 146.738 95.968  110.053 1.00 16.09  ? 172  ARG   C N     1 
ATOM   348  C CA    . ARG   A 1 172  ? 147.153 97.237  110.636 1.00 14.97  ? 172  ARG   C CA    1 
ATOM   349  C C     . ARG   A 1 172  ? 147.349 98.316  109.581 1.00 13.46  ? 172  ARG   C C     1 
ATOM   350  O O     . ARG   A 1 172  ? 147.875 98.058  108.497 1.00 14.94  ? 172  ARG   C O     1 
ATOM   351  C CB    . ARG   A 1 172  ? 148.427 97.062  111.444 1.00 20.20  ? 172  ARG   C CB    1 
ATOM   352  C CG    . ARG   A 1 172  ? 148.264 96.220  112.699 1.00 18.51  ? 172  ARG   C CG    1 
ATOM   353  C CD    . ARG   A 1 172  ? 149.542 96.068  113.442 1.00 21.36  ? 172  ARG   C CD    1 
ATOM   354  N NE    . ARG   A 1 172  ? 150.510 95.258  112.712 1.00 19.15  ? 172  ARG   C NE    1 
ATOM   355  C CZ    . ARG   A 1 172  ? 151.789 95.057  113.095 1.00 24.33  ? 172  ARG   C CZ    1 
ATOM   356  N NH1   . ARG   A 1 172  ? 152.245 95.614  114.196 1.00 28.25  ? 172  ARG   C NH1   1 
ATOM   357  N NH2   . ARG   A 1 172  ? 152.589 94.304  112.359 1.00 18.17  ? 172  ARG   C NH2   1 
ATOM   358  N N     . LEU   A 1 173  ? 146.926 99.532  109.911 1.00 14.29  ? 173  LEU   C N     1 
ATOM   359  C CA    . LEU   A 1 173  ? 147.091 100.675 109.026 1.00 12.38  ? 173  LEU   C CA    1 
ATOM   360  C C     . LEU   A 1 173  ? 148.086 101.662 109.606 1.00 15.33  ? 173  LEU   C C     1 
ATOM   361  O O     . LEU   A 1 173  ? 147.880 102.194 110.698 1.00 19.15  ? 173  LEU   C O     1 
ATOM   362  C CB    . LEU   A 1 173  ? 145.754 101.394 108.817 1.00 13.03  ? 173  LEU   C CB    1 
ATOM   363  C CG    . LEU   A 1 173  ? 144.602 100.570 108.239 1.00 11.01  ? 173  LEU   C CG    1 
ATOM   364  C CD1   . LEU   A 1 173  ? 143.358 101.454 108.138 1.00 13.08  ? 173  LEU   C CD1   1 
ATOM   365  C CD2   . LEU   A 1 173  ? 144.989 100.033 106.886 1.00 11.81  ? 173  LEU   C CD2   1 
ATOM   366  N N     . ILE   A 1 174  ? 149.164 101.907 108.880 1.00 13.01  ? 174  ILE   C N     1 
ATOM   367  C CA    . ILE   A 1 174  ? 150.191 102.828 109.347 1.00 11.80  ? 174  ILE   C CA    1 
ATOM   368  C C     . ILE   A 1 174  ? 150.235 104.070 108.474 1.00 12.97  ? 174  ILE   C C     1 
ATOM   369  O O     . ILE   A 1 174  ? 150.372 103.975 107.255 1.00 16.47  ? 174  ILE   C O     1 
ATOM   370  C CB    . ILE   A 1 174  ? 151.571 102.144 109.353 1.00 13.37  ? 174  ILE   C CB    1 
ATOM   371  C CG1   . ILE   A 1 174  ? 151.518 100.840 110.191 1.00 17.40  ? 174  ILE   C CG1   1 
ATOM   372  C CG2   . ILE   A 1 174  ? 152.643 103.093 109.875 1.00 23.62  ? 174  ILE   C CG2   1 
ATOM   373  C CD1   . ILE   A 1 174  ? 151.157 101.013 111.653 1.00 23.83  ? 174  ILE   C CD1   1 
ATOM   374  N N     . LYS   A 1 175  ? 150.121 105.238 109.092 1.00 15.04  ? 175  LYS   C N     1 
ATOM   375  C CA    . LYS   A 1 175  ? 150.165 106.478 108.331 1.00 13.16  ? 175  LYS   C CA    1 
ATOM   376  C C     . LYS   A 1 175  ? 151.575 106.736 107.824 1.00 14.09  ? 175  LYS   C C     1 
ATOM   377  O O     . LYS   A 1 175  ? 152.543 106.641 108.578 1.00 19.95  ? 175  LYS   C O     1 
ATOM   378  C CB    . LYS   A 1 175  ? 149.688 107.652 109.179 1.00 16.91  ? 175  LYS   C CB    1 
ATOM   379  C CG    . LYS   A 1 175  ? 149.671 108.985 108.443 1.00 17.75  ? 175  LYS   C CG    1 
ATOM   380  C CD    . LYS   A 1 175  ? 149.197 110.114 109.345 1.00 32.59  ? 175  LYS   C CD    1 
ATOM   381  C CE    . LYS   A 1 175  ? 149.320 111.461 108.641 1.00 47.64  ? 175  LYS   C CE    1 
ATOM   382  N NZ    . LYS   A 1 175  ? 148.957 112.601 109.535 1.00 59.39  ? 175  LYS   C NZ    1 
ATOM   383  N N     . GLU   A 1 176  ? 151.694 107.090 106.552 1.00 13.85  ? 176  GLU   C N     1 
ATOM   384  C CA    . GLU   A 1 176  ? 152.998 107.370 105.974 1.00 14.98  ? 176  GLU   C CA    1 
ATOM   385  C C     . GLU   A 1 176  ? 153.343 108.849 106.090 1.00 21.05  ? 176  GLU   C C     1 
ATOM   386  O O     . GLU   A 1 176  ? 152.801 109.688 105.370 1.00 19.41  ? 176  GLU   C O     1 
ATOM   387  C CB    . GLU   A 1 176  ? 153.043 106.924 104.513 1.00 13.09  ? 176  GLU   C CB    1 
ATOM   388  C CG    . GLU   A 1 176  ? 154.387 107.130 103.838 1.00 16.53  ? 176  GLU   C CG    1 
ATOM   389  C CD    . GLU   A 1 176  ? 154.421 106.618 102.428 1.00 23.43  ? 176  GLU   C CD    1 
ATOM   390  O OE1   . GLU   A 1 176  ? 153.484 105.969 102.027 1.00 19.55  ? 176  GLU   C OE1   1 
ATOM   391  O OE2   . GLU   A 1 176  ? 155.384 106.876 101.747 1.00 28.79  ? 176  GLU   C OE2   1 
ATOM   392  N N     . SER   A 1 201  ? 152.960 105.157 113.108 1.00 24.46  ? 201  SER   C N     1 
ATOM   393  C CA    . SER   A 1 201  ? 151.771 105.920 113.457 1.00 23.82  ? 201  SER   C CA    1 
ATOM   394  C C     . SER   A 1 201  ? 150.492 105.170 113.089 1.00 21.46  ? 201  SER   C C     1 
ATOM   395  O O     . SER   A 1 201  ? 149.901 105.433 112.045 1.00 21.17  ? 201  SER   C O     1 
ATOM   396  C CB    . SER   A 1 201  ? 151.800 107.260 112.747 1.00 22.26  ? 201  SER   C CB    1 
ATOM   397  O OG    . SER   A 1 201  ? 152.867 108.044 113.206 1.00 30.76  ? 201  SER   C OG    1 
ATOM   398  N N     . PRO   A 1 202  ? 150.061 104.212 113.924 1.00 23.07  ? 202  PRO   C N     1 
ATOM   399  C CA    . PRO   A 1 202  ? 148.851 103.419 113.773 1.00 22.99  ? 202  PRO   C CA    1 
ATOM   400  C C     . PRO   A 1 202  ? 147.607 104.298 113.726 1.00 22.43  ? 202  PRO   C C     1 
ATOM   401  O O     . PRO   A 1 202  ? 147.469 105.232 114.509 1.00 22.93  ? 202  PRO   C O     1 
ATOM   402  C CB    . PRO   A 1 202  ? 148.861 102.550 115.042 1.00 24.85  ? 202  PRO   C CB    1 
ATOM   403  C CG    . PRO   A 1 202  ? 150.308 102.496 115.456 1.00 26.78  ? 202  PRO   C CG    1 
ATOM   404  C CD    . PRO   A 1 202  ? 150.860 103.862 115.098 1.00 26.07  ? 202  PRO   C CD    1 
ATOM   405  N N     . ILE   A 1 203  ? 146.700 103.961 112.819 1.00 21.03  ? 203  ILE   C N     1 
ATOM   406  C CA    . ILE   A 1 203  ? 145.436 104.676 112.685 1.00 19.30  ? 203  ILE   C CA    1 
ATOM   407  C C     . ILE   A 1 203  ? 144.272 103.697 112.627 1.00 22.70  ? 203  ILE   C C     1 
ATOM   408  O O     . ILE   A 1 203  ? 144.463 102.486 112.523 1.00 23.91  ? 203  ILE   C O     1 
ATOM   409  C CB    . ILE   A 1 203  ? 145.449 105.601 111.458 1.00 16.27  ? 203  ILE   C CB    1 
ATOM   410  C CG1   . ILE   A 1 203  ? 145.648 104.789 110.195 1.00 17.56  ? 203  ILE   C CG1   1 
ATOM   411  C CG2   . ILE   A 1 203  ? 146.543 106.651 111.620 1.00 24.60  ? 203  ILE   C CG2   1 
ATOM   412  C CD1   . ILE   A 1 203  ? 145.515 105.586 108.937 1.00 21.29  ? 203  ILE   C CD1   1 
ATOM   413  N N     . LYS   A 1 204  ? 143.058 104.219 112.733 1.00 21.57  ? 204  LYS   C N     1 
ATOM   414  C CA    . LYS   A 1 204  ? 141.859 103.391 112.690 1.00 23.51  ? 204  LYS   C CA    1 
ATOM   415  C C     . LYS   A 1 204  ? 141.253 103.369 111.291 1.00 23.95  ? 204  LYS   C C     1 
ATOM   416  O O     . LYS   A 1 204  ? 141.634 104.165 110.435 1.00 24.13  ? 204  LYS   C O     1 
ATOM   417  C CB    . LYS   A 1 204  ? 140.835 103.889 113.710 1.00 27.16  ? 204  LYS   C CB    1 
ATOM   418  C CG    . LYS   A 1 204  ? 141.300 103.799 115.156 1.00 27.77  ? 204  LYS   C CG    1 
ATOM   419  C CD    . LYS   A 1 204  ? 140.210 104.256 116.116 1.00 35.64  ? 204  LYS   C CD    1 
ATOM   420  C CE    . LYS   A 1 204  ? 140.691 104.191 117.560 1.00 44.71  ? 204  LYS   C CE    1 
ATOM   421  N NZ    . LYS   A 1 204  ? 139.619 104.585 118.519 1.00 43.87  ? 204  LYS   C NZ    1 
ATOM   422  N N     . MET   A 1 205  ? 140.308 102.455 111.060 1.00 25.67  ? 205  MET   C N     1 
ATOM   423  C CA    . MET   A 1 205  ? 139.573 102.430 109.794 1.00 24.31  ? 205  MET   C CA    1 
ATOM   424  C C     . MET   A 1 205  ? 138.739 103.695 109.659 1.00 23.22  ? 205  MET   C C     1 
ATOM   425  O O     . MET   A 1 205  ? 138.529 104.198 108.556 1.00 24.51  ? 205  MET   C O     1 
ATOM   426  C CB    . MET   A 1 205  ? 138.682 101.197 109.698 1.00 26.56  ? 205  MET   C CB    1 
ATOM   427  C CG    . MET   A 1 205  ? 139.427 99.879  109.510 1.00 29.56  ? 205  MET   C CG    1 
ATOM   428  S SD    . MET   A 1 205  ? 138.333 98.427  109.541 1.00 31.59  ? 205  MET   C SD    1 
ATOM   429  C CE    . MET   A 1 205  ? 137.371 98.634  108.047 1.00 17.49  ? 205  MET   C CE    1 
ATOM   430  N N     . GLU   A 1 206  ? 138.269 104.210 110.787 1.00 21.79  ? 206  GLU   C N     1 
ATOM   431  C CA    . GLU   A 1 206  ? 137.564 105.478 110.806 1.00 20.71  ? 206  GLU   C CA    1 
ATOM   432  C C     . GLU   A 1 206  ? 138.563 106.595 111.087 1.00 23.31  ? 206  GLU   C C     1 
ATOM   433  O O     . GLU   A 1 206  ? 139.748 106.333 111.270 1.00 24.89  ? 206  GLU   C O     1 
ATOM   434  C CB    . GLU   A 1 206  ? 136.443 105.461 111.849 1.00 20.31  ? 206  GLU   C CB    1 
ATOM   435  C CG    . GLU   A 1 206  ? 136.897 105.279 113.299 1.00 29.07  ? 206  GLU   C CG    1 
ATOM   436  C CD    . GLU   A 1 206  ? 137.096 103.844 113.702 1.00 30.33  ? 206  GLU   C CD    1 
ATOM   437  O OE1   . GLU   A 1 206  ? 137.323 103.027 112.843 1.00 30.14  ? 206  GLU   C OE1   1 
ATOM   438  O OE2   . GLU   A 1 206  ? 137.029 103.567 114.876 1.00 28.31  ? 206  GLU   C OE2   1 
ATOM   439  N N     . LEU   A 1 207  ? 138.089 107.839 111.109 1.00 22.80  ? 207  LEU   C N     1 
ATOM   440  C CA    . LEU   A 1 207  ? 138.950 109.008 111.320 1.00 27.64  ? 207  LEU   C CA    1 
ATOM   441  C C     . LEU   A 1 207  ? 139.957 109.215 110.182 1.00 27.64  ? 207  LEU   C C     1 
ATOM   442  O O     . LEU   A 1 207  ? 140.918 109.972 110.330 1.00 30.64  ? 207  LEU   C O     1 
ATOM   443  C CB    . LEU   A 1 207  ? 139.743 108.878 112.635 1.00 25.61  ? 207  LEU   C CB    1 
ATOM   444  C CG    . LEU   A 1 207  ? 138.939 108.594 113.916 1.00 28.14  ? 207  LEU   C CG    1 
ATOM   445  C CD1   . LEU   A 1 207  ? 139.913 108.365 115.064 1.00 25.89  ? 207  LEU   C CD1   1 
ATOM   446  C CD2   . LEU   A 1 207  ? 138.013 109.752 114.217 1.00 34.98  ? 207  LEU   C CD2   1 
ATOM   447  N N     . LEU   A 1 208  ? 139.728 108.564 109.043 1.00 23.18  ? 208  LEU   C N     1 
ATOM   448  C CA    . LEU   A 1 208  ? 140.639 108.681 107.910 1.00 21.73  ? 208  LEU   C CA    1 
ATOM   449  C C     . LEU   A 1 208  ? 140.517 110.022 107.210 1.00 26.65  ? 208  LEU   C C     1 
ATOM   450  O O     . LEU   A 1 208  ? 141.492 110.541 106.673 1.00 29.06  ? 208  LEU   C O     1 
ATOM   451  C CB    . LEU   A 1 208  ? 140.372 107.583 106.876 1.00 19.54  ? 208  LEU   C CB    1 
ATOM   452  C CG    . LEU   A 1 208  ? 140.694 106.155 107.282 1.00 16.54  ? 208  LEU   C CG    1 
ATOM   453  C CD1   . LEU   A 1 208  ? 140.138 105.217 106.237 1.00 16.67  ? 208  LEU   C CD1   1 
ATOM   454  C CD2   . LEU   A 1 208  ? 142.192 105.971 107.396 1.00 16.74  ? 208  LEU   C CD2   1 
ATOM   455  N N     . PHE   A 1 209  ? 139.314 110.577 107.198 1.00 25.42  ? 209  PHE   C N     1 
ATOM   456  C CA    . PHE   A 1 209  ? 139.079 111.799 106.446 1.00 29.18  ? 209  PHE   C CA    1 
ATOM   457  C C     . PHE   A 1 209  ? 139.057 113.033 107.351 1.00 35.44  ? 209  PHE   C C     1 
ATOM   458  O O     . PHE   A 1 209  ? 138.876 114.162 106.884 1.00 36.83  ? 209  PHE   C O     1 
ATOM   459  C CB    . PHE   A 1 209  ? 137.764 111.670 105.681 1.00 26.09  ? 209  PHE   C CB    1 
ATOM   460  C CG    . PHE   A 1 209  ? 137.759 110.513 104.716 1.00 15.31  ? 209  PHE   C CG    1 
ATOM   461  C CD1   . PHE   A 1 209  ? 137.234 109.294 105.092 1.00 14.83  ? 209  PHE   C CD1   1 
ATOM   462  C CD2   . PHE   A 1 209  ? 138.277 110.640 103.443 1.00 15.60  ? 209  PHE   C CD2   1 
ATOM   463  C CE1   . PHE   A 1 209  ? 137.233 108.230 104.224 1.00 14.80  ? 209  PHE   C CE1   1 
ATOM   464  C CE2   . PHE   A 1 209  ? 138.276 109.577 102.571 1.00 12.53  ? 209  PHE   C CE2   1 
ATOM   465  C CZ    . PHE   A 1 209  ? 137.755 108.370 102.965 1.00 9.85   ? 209  PHE   C CZ    1 
ATOM   466  N N     . ASP   A 1 210  ? 139.246 112.816 108.651 1.00 37.27  ? 210  ASP   C N     1 
ATOM   467  C CA    . ASP   A 1 210  ? 139.236 113.913 109.613 1.00 42.03  ? 210  ASP   C CA    1 
ATOM   468  C C     . ASP   A 1 210  ? 140.449 114.828 109.431 1.00 45.27  ? 210  ASP   C C     1 
ATOM   469  O O     . ASP   A 1 210  ? 141.508 114.367 109.005 1.00 43.21  ? 210  ASP   C O     1 
ATOM   470  C CB    . ASP   A 1 210  ? 139.228 113.385 111.048 1.00 41.93  ? 210  ASP   C CB    1 
ATOM   471  C CG    . ASP   A 1 210  ? 137.892 112.811 111.476 1.00 40.31  ? 210  ASP   C CG    1 
ATOM   472  O OD1   . ASP   A 1 210  ? 136.927 112.952 110.756 1.00 38.23  ? 210  ASP   C OD1   1 
ATOM   473  O OD2   . ASP   A 1 210  ? 137.839 112.250 112.536 1.00 39.49  ? 210  ASP   C OD2   1 
ATOM   474  N N     . PRO   A 1 211  ? 140.321 116.120 109.768 1.00 48.01  ? 211  PRO   C N     1 
ATOM   475  C CA    . PRO   A 1 211  ? 141.386 117.097 109.860 1.00 56.50  ? 211  PRO   C CA    1 
ATOM   476  C C     . PRO   A 1 211  ? 142.460 116.629 110.828 1.00 57.60  ? 211  PRO   C C     1 
ATOM   477  O O     . PRO   A 1 211  ? 142.157 115.984 111.831 1.00 59.51  ? 211  PRO   C O     1 
ATOM   478  C CB    . PRO   A 1 211  ? 140.659 118.335 110.397 1.00 60.05  ? 211  PRO   C CB    1 
ATOM   479  C CG    . PRO   A 1 211  ? 139.229 118.162 109.971 1.00 54.52  ? 211  PRO   C CG    1 
ATOM   480  C CD    . PRO   A 1 211  ? 138.979 116.672 110.019 1.00 49.35  ? 211  PRO   C CD    1 
ATOM   481  N N     . ASP   A 1 212  ? 143.712 116.953 110.521 1.00 68.45  ? 212  ASP   C N     1 
ATOM   482  C CA    . ASP   A 1 212  ? 144.834 116.565 111.362 1.00 82.63  ? 212  ASP   C CA    1 
ATOM   483  C C     . ASP   A 1 212  ? 145.175 117.635 112.403 1.00 86.54  ? 212  ASP   C C     1 
ATOM   484  O O     . ASP   A 1 212  ? 144.371 118.528 112.678 1.00 84.04  ? 212  ASP   C O     1 
ATOM   485  C CB    . ASP   A 1 212  ? 146.046 116.176 110.502 1.00 85.15  ? 212  ASP   C CB    1 
ATOM   486  C CG    . ASP   A 1 212  ? 146.589 117.299 109.672 1.00 84.52  ? 212  ASP   C CG    1 
ATOM   487  O OD1   . ASP   A 1 212  ? 146.176 118.403 109.885 1.00 85.14  ? 212  ASP   C OD1   1 
ATOM   488  O OD2   . ASP   A 1 212  ? 147.415 117.046 108.825 1.00 85.87  ? 212  ASP   C OD2   1 
ATOM   489  N N     . ASP   A 1 213  ? 146.339 117.488 113.035 1.00 91.57  ? 213  ASP   C N     1 
ATOM   490  C CA    . ASP   A 1 213  ? 146.738 118.271 114.204 1.00 99.85  ? 213  ASP   C CA    1 
ATOM   491  C C     . ASP   A 1 213  ? 146.833 119.786 114.012 1.00 103.80 ? 213  ASP   C C     1 
ATOM   492  O O     . ASP   A 1 213  ? 146.596 120.534 114.961 1.00 104.30 ? 213  ASP   C O     1 
ATOM   493  C CB    . ASP   A 1 213  ? 148.090 117.769 114.709 1.00 106.29 ? 213  ASP   C CB    1 
ATOM   494  C CG    . ASP   A 1 213  ? 148.017 116.386 115.340 1.00 103.45 ? 213  ASP   C CG    1 
ATOM   495  O OD1   . ASP   A 1 213  ? 146.935 115.929 115.624 1.00 103.45 ? 213  ASP   C OD1   1 
ATOM   496  O OD2   . ASP   A 1 213  ? 149.051 115.795 115.527 1.00 110.86 ? 213  ASP   C OD2   1 
ATOM   497  N N     . GLU   A 1 214  ? 147.210 120.249 112.824 1.00 101.04 ? 214  GLU   C N     1 
ATOM   498  C CA    . GLU   A 1 214  ? 147.395 121.687 112.622 1.00 99.30  ? 214  GLU   C CA    1 
ATOM   499  C C     . GLU   A 1 214  ? 146.703 122.155 111.350 1.00 133.32 ? 214  GLU   C C     1 
ATOM   500  O O     . GLU   A 1 214  ? 146.502 121.375 110.425 1.00 92.23  ? 214  GLU   C O     1 
ATOM   501  C CB    . GLU   A 1 214  ? 148.894 122.028 112.588 1.00 111.49 ? 214  GLU   C CB    1 
ATOM   502  C CG    . GLU   A 1 214  ? 149.226 123.519 112.426 1.00 111.21 ? 214  GLU   C CG    1 
ATOM   503  C CD    . GLU   A 1 214  ? 148.672 124.382 113.527 1.00 105.38 ? 214  GLU   C CD    1 
ATOM   504  O OE1   . GLU   A 1 214  ? 149.408 124.730 114.420 1.00 112.45 ? 214  GLU   C OE1   1 
ATOM   505  O OE2   . GLU   A 1 214  ? 147.500 124.690 113.472 1.00 116.13 ? 214  GLU   C OE2   1 
ATOM   506  N N     . HIS   A 1 215  ? 146.303 123.428 111.325 1.00 94.64  ? 215  HIS   C N     1 
ATOM   507  C CA    . HIS   A 1 215  ? 145.588 124.045 110.199 1.00 85.67  ? 215  HIS   C CA    1 
ATOM   508  C C     . HIS   A 1 215  ? 144.138 123.557 110.092 1.00 146.06 ? 215  HIS   C C     1 
ATOM   509  O O     . HIS   A 1 215  ? 143.285 124.244 109.531 1.00 90.81  ? 215  HIS   C O     1 
ATOM   510  C CB    . HIS   A 1 215  ? 146.308 123.796 108.865 1.00 97.95  ? 215  HIS   C CB    1 
ATOM   511  C CG    . HIS   A 1 215  ? 147.737 124.234 108.845 1.00 110.41 ? 215  HIS   C CG    1 
ATOM   512  N ND1   . HIS   A 1 215  ? 148.112 125.561 108.926 1.00 116.30 ? 215  HIS   C ND1   1 
ATOM   513  C CD2   . HIS   A 1 215  ? 148.884 123.524 108.750 1.00 112.14 ? 215  HIS   C CD2   1 
ATOM   514  C CE1   . HIS   A 1 215  ? 149.430 125.645 108.882 1.00 116.24 ? 215  HIS   C CE1   1 
ATOM   515  N NE2   . HIS   A 1 215  ? 149.922 124.423 108.776 1.00 115.91 ? 215  HIS   C NE2   1 
ATOM   516  N N     . SER   A 1 216  ? 143.869 122.374 110.642 1.00 91.90  ? 216  SER   C N     1 
ATOM   517  C CA    . SER   A 1 216  ? 142.545 121.770 110.661 1.00 82.39  ? 216  SER   C CA    1 
ATOM   518  C C     . SER   A 1 216  ? 141.945 121.649 109.266 1.00 80.56  ? 216  SER   C C     1 
ATOM   519  O O     . SER   A 1 216  ? 140.746 121.859 109.077 1.00 71.92  ? 216  SER   C O     1 
ATOM   520  C CB    . SER   A 1 216  ? 141.617 122.573 111.554 1.00 85.22  ? 216  SER   C CB    1 
ATOM   521  O OG    . SER   A 1 216  ? 142.105 122.632 112.869 1.00 84.78  ? 216  SER   C OG    1 
ATOM   522  N N     . GLU   A 1 217  ? 142.771 121.278 108.295 1.00 78.54  ? 217  GLU   C N     1 
ATOM   523  C CA    . GLU   A 1 217  ? 142.302 121.079 106.931 1.00 71.28  ? 217  GLU   C CA    1 
ATOM   524  C C     . GLU   A 1 217  ? 141.760 119.655 106.761 1.00 63.26  ? 217  GLU   C C     1 
ATOM   525  O O     . GLU   A 1 217  ? 142.451 118.701 107.116 1.00 62.97  ? 217  GLU   C O     1 
ATOM   526  C CB    . GLU   A 1 217  ? 143.441 121.322 105.937 1.00 77.28  ? 217  GLU   C CB    1 
ATOM   527  C CG    . GLU   A 1 217  ? 143.937 122.760 105.892 1.00 86.27  ? 217  GLU   C CG    1 
ATOM   528  C CD    . GLU   A 1 217  ? 145.062 122.964 104.910 1.00 92.53  ? 217  GLU   C CD    1 
ATOM   529  O OE1   . GLU   A 1 217  ? 145.479 122.002 104.312 1.00 88.04  ? 217  GLU   C OE1   1 
ATOM   530  O OE2   . GLU   A 1 217  ? 145.504 124.079 104.760 1.00 88.92  ? 217  GLU   C OE2   1 
ATOM   531  N N     . PRO   A 1 218  ? 140.551 119.489 106.209 1.00 56.93  ? 218  PRO   C N     1 
ATOM   532  C CA    . PRO   A 1 218  ? 139.867 118.226 105.991 1.00 53.68  ? 218  PRO   C CA    1 
ATOM   533  C C     . PRO   A 1 218  ? 140.549 117.440 104.888 1.00 48.60  ? 218  PRO   C C     1 
ATOM   534  O O     . PRO   A 1 218  ? 141.213 118.023 104.031 1.00 47.73  ? 218  PRO   C O     1 
ATOM   535  C CB    . PRO   A 1 218  ? 138.460 118.676 105.592 1.00 51.45  ? 218  PRO   C CB    1 
ATOM   536  C CG    . PRO   A 1 218  ? 138.657 120.041 104.970 1.00 59.43  ? 218  PRO   C CG    1 
ATOM   537  C CD    . PRO   A 1 218  ? 139.814 120.665 105.732 1.00 60.62  ? 218  PRO   C CD    1 
ATOM   538  N N     . VAL   A 1 219  ? 140.381 116.122 104.902 1.00 40.27  ? 219  VAL   C N     1 
ATOM   539  C CA    . VAL   A 1 219  ? 140.992 115.277 103.890 1.00 31.25  ? 219  VAL   C CA    1 
ATOM   540  C C     . VAL   A 1 219  ? 139.957 114.697 102.945 1.00 27.86  ? 219  VAL   C C     1 
ATOM   541  O O     . VAL   A 1 219  ? 139.065 113.962 103.362 1.00 27.74  ? 219  VAL   C O     1 
ATOM   542  C CB    . VAL   A 1 219  ? 141.766 114.138 104.574 1.00 28.54  ? 219  VAL   C CB    1 
ATOM   543  C CG1   . VAL   A 1 219  ? 142.370 113.201 103.537 1.00 24.98  ? 219  VAL   C CG1   1 
ATOM   544  C CG2   . VAL   A 1 219  ? 142.846 114.730 105.456 1.00 34.63  ? 219  VAL   C CG2   1 
ATOM   545  N N     . HIS   A 1 220  ? 140.082 115.015 101.665 1.00 25.78  ? 220  HIS   C N     1 
ATOM   546  C CA    . HIS   A 1 220  ? 139.149 114.503 100.675 1.00 20.46  ? 220  HIS   C CA    1 
ATOM   547  C C     . HIS   A 1 220  ? 139.601 113.162 100.124 1.00 18.47  ? 220  HIS   C C     1 
ATOM   548  O O     . HIS   A 1 220  ? 138.777 112.296 99.823  1.00 18.37  ? 220  HIS   C O     1 
ATOM   549  C CB    . HIS   A 1 220  ? 139.001 115.484 99.514  1.00 24.00  ? 220  HIS   C CB    1 
ATOM   550  C CG    . HIS   A 1 220  ? 138.422 116.787 99.901  1.00 30.10  ? 220  HIS   C CG    1 
ATOM   551  N ND1   . HIS   A 1 220  ? 139.183 117.814 100.411 1.00 35.96  ? 220  HIS   C ND1   1 
ATOM   552  C CD2   . HIS   A 1 220  ? 137.154 117.243 99.855  1.00 32.30  ? 220  HIS   C CD2   1 
ATOM   553  C CE1   . HIS   A 1 220  ? 138.404 118.851 100.659 1.00 40.96  ? 220  HIS   C CE1   1 
ATOM   554  N NE2   . HIS   A 1 220  ? 137.168 118.531 100.330 1.00 37.75  ? 220  HIS   C NE2   1 
ATOM   555  N N     . THR   A 1 221  ? 140.912 113.003 99.969  1.00 15.42  ? 221  THR   C N     1 
ATOM   556  C CA    . THR   A 1 221  ? 141.453 111.810 99.339  1.00 10.33  ? 221  THR   C CA    1 
ATOM   557  C C     . THR   A 1 221  ? 142.369 111.032 100.261 1.00 12.52  ? 221  THR   C C     1 
ATOM   558  O O     . THR   A 1 221  ? 143.304 111.584 100.845 1.00 17.33  ? 221  THR   C O     1 
ATOM   559  C CB    . THR   A 1 221  ? 142.221 112.171 98.056  1.00 11.50  ? 221  THR   C CB    1 
ATOM   560  O OG1   . THR   A 1 221  ? 141.337 112.828 97.147  1.00 16.70  ? 221  THR   C OG1   1 
ATOM   561  C CG2   . THR   A 1 221  ? 142.766 110.914 97.395  1.00 11.79  ? 221  THR   C CG2   1 
ATOM   562  N N     . VAL   A 1 222  ? 142.101 109.741 100.366 1.00 10.13  ? 222  VAL   C N     1 
ATOM   563  C CA    . VAL   A 1 222  ? 142.919 108.830 101.151 1.00 6.89   ? 222  VAL   C CA    1 
ATOM   564  C C     . VAL   A 1 222  ? 143.429 107.719 100.251 1.00 8.55   ? 222  VAL   C C     1 
ATOM   565  O O     . VAL   A 1 222  ? 142.659 107.129 99.497  1.00 8.78   ? 222  VAL   C O     1 
ATOM   566  C CB    . VAL   A 1 222  ? 142.108 108.245 102.317 1.00 7.02   ? 222  VAL   C CB    1 
ATOM   567  C CG1   . VAL   A 1 222  ? 142.945 107.252 103.092 1.00 6.93   ? 222  VAL   C CG1   1 
ATOM   568  C CG2   . VAL   A 1 222  ? 141.656 109.373 103.227 1.00 14.37  ? 222  VAL   C CG2   1 
ATOM   569  N N     . VAL   A 1 223  ? 144.726 107.454 100.297 1.00 6.84   ? 223  VAL   C N     1 
ATOM   570  C CA    . VAL   A 1 223  ? 145.297 106.436 99.430  1.00 0.23   ? 223  VAL   C CA    1 
ATOM   571  C C     . VAL   A 1 223  ? 145.915 105.305 100.231 1.00 0.75   ? 223  VAL   C C     1 
ATOM   572  O O     . VAL   A 1 223  ? 146.827 105.518 101.029 1.00 0.00   ? 223  VAL   C O     1 
ATOM   573  C CB    . VAL   A 1 223  ? 146.363 107.058 98.514  1.00 7.42   ? 223  VAL   C CB    1 
ATOM   574  C CG1   . VAL   A 1 223  ? 146.955 105.998 97.600  1.00 9.45   ? 223  VAL   C CG1   1 
ATOM   575  C CG2   . VAL   A 1 223  ? 145.738 108.167 97.711  1.00 7.56   ? 223  VAL   C CG2   1 
ATOM   576  N N     . PHE   A 1 224  ? 145.423 104.100 99.999  1.00 0.07   ? 224  PHE   C N     1 
ATOM   577  C CA    . PHE   A 1 224  ? 145.929 102.907 100.653 1.00 0.02   ? 224  PHE   C CA    1 
ATOM   578  C C     . PHE   A 1 224  ? 146.881 102.188 99.731  1.00 0.03   ? 224  PHE   C C     1 
ATOM   579  O O     . PHE   A 1 224  ? 146.571 101.974 98.558  1.00 0.06   ? 224  PHE   C O     1 
ATOM   580  C CB    . PHE   A 1 224  ? 144.800 101.940 100.998 1.00 0.04   ? 224  PHE   C CB    1 
ATOM   581  C CG    . PHE   A 1 224  ? 143.894 102.323 102.128 1.00 0.02   ? 224  PHE   C CG    1 
ATOM   582  C CD1   . PHE   A 1 224  ? 144.066 103.477 102.861 1.00 3.45   ? 224  PHE   C CD1   1 
ATOM   583  C CD2   . PHE   A 1 224  ? 142.855 101.490 102.463 1.00 0.52   ? 224  PHE   C CD2   1 
ATOM   584  C CE1   . PHE   A 1 224  ? 143.219 103.774 103.899 1.00 13.76  ? 224  PHE   C CE1   1 
ATOM   585  C CE2   . PHE   A 1 224  ? 142.015 101.788 103.492 1.00 11.46  ? 224  PHE   C CE2   1 
ATOM   586  C CZ    . PHE   A 1 224  ? 142.199 102.925 104.210 1.00 8.55   ? 224  PHE   C CZ    1 
ATOM   587  N N     . GLN   A 1 225  ? 148.020 101.774 100.254 1.00 1.28   ? 225  GLN   C N     1 
ATOM   588  C CA    . GLN   A 1 225  ? 148.953 101.045 99.419  1.00 3.79   ? 225  GLN   C CA    1 
ATOM   589  C C     . GLN   A 1 225  ? 149.502 99.804  100.090 1.00 8.10   ? 225  GLN   C C     1 
ATOM   590  O O     . GLN   A 1 225  ? 149.637 99.741  101.312 1.00 11.96  ? 225  GLN   C O     1 
ATOM   591  C CB    . GLN   A 1 225  ? 150.110 101.947 98.995  1.00 6.73   ? 225  GLN   C CB    1 
ATOM   592  C CG    . GLN   A 1 225  ? 150.955 102.430 100.139 1.00 7.46   ? 225  GLN   C CG    1 
ATOM   593  C CD    . GLN   A 1 225  ? 152.103 103.280 99.679  1.00 8.23   ? 225  GLN   C CD    1 
ATOM   594  O OE1   . GLN   A 1 225  ? 152.711 103.007 98.641  1.00 12.10  ? 225  GLN   C OE1   1 
ATOM   595  N NE2   . GLN   A 1 225  ? 152.413 104.309 100.449 1.00 10.28  ? 225  GLN   C NE2   1 
ATOM   596  N N     . GLY   A 1 226  ? 149.869 98.830  99.273  1.00 9.62   ? 226  GLY   C N     1 
ATOM   597  C CA    . GLY   A 1 226  ? 150.518 97.630  99.782  1.00 11.41  ? 226  GLY   C CA    1 
ATOM   598  C C     . GLY   A 1 226  ? 150.855 96.633  98.683  1.00 14.44  ? 226  GLY   C C     1 
ATOM   599  O O     . GLY   A 1 226  ? 150.383 96.744  97.550  1.00 17.68  ? 226  GLY   C O     1 
ATOM   600  N N     . ALA   A 1 227  ? 151.675 95.655  99.041  1.00 14.16  ? 227  ALA   C N     1 
ATOM   601  C CA    . ALA   A 1 227  ? 152.151 94.627  98.122  1.00 21.41  ? 227  ALA   C CA    1 
ATOM   602  C C     . ALA   A 1 227  ? 151.026 93.695  97.695  1.00 18.51  ? 227  ALA   C C     1 
ATOM   603  O O     . ALA   A 1 227  ? 149.985 93.611  98.347  1.00 21.36  ? 227  ALA   C O     1 
ATOM   604  C CB    . ALA   A 1 227  ? 153.262 93.824  98.776  1.00 16.12  ? 227  ALA   C CB    1 
ATOM   605  N N     . ALA   A 1 228  ? 151.234 93.006  96.582  1.00 18.74  ? 228  ALA   C N     1 
ATOM   606  C CA    . ALA   A 1 228  ? 150.257 92.038  96.117  1.00 23.52  ? 228  ALA   C CA    1 
ATOM   607  C C     . ALA   A 1 228  ? 150.055 90.961  97.168  1.00 17.15  ? 228  ALA   C C     1 
ATOM   608  O O     . ALA   A 1 228  ? 151.012 90.461  97.747  1.00 18.28  ? 228  ALA   C O     1 
ATOM   609  C CB    . ALA   A 1 228  ? 150.722 91.416  94.813  1.00 17.53  ? 228  ALA   C CB    1 
ATOM   610  N N     . GLY   A 1 229  ? 148.802 90.588  97.398  1.00 18.29  ? 229  GLY   C N     1 
ATOM   611  C CA    . GLY   A 1 229  ? 148.482 89.518  98.338  1.00 12.68  ? 229  GLY   C CA    1 
ATOM   612  C C     . GLY   A 1 229  ? 148.238 90.010  99.765  1.00 11.37  ? 229  GLY   C C     1 
ATOM   613  O O     . GLY   A 1 229  ? 147.864 89.220  100.636 1.00 14.15  ? 229  GLY   C O     1 
ATOM   614  N N     . ILE   A 1 230  ? 148.462 91.301  100.019 1.00 16.24  ? 230  ILE   C N     1 
ATOM   615  C CA    . ILE   A 1 230  ? 148.256 91.860  101.358 1.00 5.62   ? 230  ILE   C CA    1 
ATOM   616  C C     . ILE   A 1 230  ? 146.787 91.908  101.754 1.00 11.59  ? 230  ILE   C C     1 
ATOM   617  O O     . ILE   A 1 230  ? 146.449 91.631  102.900 1.00 15.26  ? 230  ILE   C O     1 
ATOM   618  C CB    . ILE   A 1 230  ? 148.898 93.250  101.498 1.00 5.11   ? 230  ILE   C CB    1 
ATOM   619  C CG1   . ILE   A 1 230  ? 150.447 93.139  101.385 1.00 12.74  ? 230  ILE   C CG1   1 
ATOM   620  C CG2   . ILE   A 1 230  ? 148.489 93.902  102.820 1.00 9.71   ? 230  ILE   C CG2   1 
ATOM   621  C CD1   . ILE   A 1 230  ? 151.140 92.294  102.457 1.00 10.59  ? 230  ILE   C CD1   1 
ATOM   622  N N     . GLY   A 1 231  ? 145.912 92.261  100.822 1.00 13.53  ? 231  GLY   C N     1 
ATOM   623  C CA    . GLY   A 1 231  ? 144.482 92.275  101.126 1.00 11.67  ? 231  GLY   C CA    1 
ATOM   624  C C     . GLY   A 1 231  ? 143.845 93.661  101.074 1.00 11.51  ? 231  GLY   C C     1 
ATOM   625  O O     . GLY   A 1 231  ? 142.905 93.947  101.817 1.00 14.68  ? 231  GLY   C O     1 
ATOM   626  N N     . LYS   A 1 232  ? 144.340 94.507  100.179 1.00 11.77  ? 232  LYS   C N     1 
ATOM   627  C CA    . LYS   A 1 232  ? 143.811 95.856  100.001 1.00 11.62  ? 232  LYS   C CA    1 
ATOM   628  C C     . LYS   A 1 232  ? 142.314 95.836  99.699  1.00 12.47  ? 232  LYS   C C     1 
ATOM   629  O O     . LYS   A 1 232  ? 141.550 96.643  100.231 1.00 16.73  ? 232  LYS   C O     1 
ATOM   630  C CB    . LYS   A 1 232  ? 144.526 96.552  98.842  1.00 11.68  ? 232  LYS   C CB    1 
ATOM   631  C CG    . LYS   A 1 232  ? 146.030 96.745  99.019  1.00 12.60  ? 232  LYS   C CG    1 
ATOM   632  C CD    . LYS   A 1 232  ? 146.641 97.534  97.855  1.00 11.27  ? 232  LYS   C CD    1 
ATOM   633  C CE    . LYS   A 1 232  ? 146.810 96.670  96.608  1.00 13.77  ? 232  LYS   C CE    1 
ATOM   634  N NZ    . LYS   A 1 232  ? 147.867 95.643  96.787  1.00 16.63  ? 232  LYS   C NZ    1 
ATOM   635  N N     . THR   A 1 233  ? 141.909 94.924  98.819  1.00 13.46  ? 233  THR   C N     1 
ATOM   636  C CA    . THR   A 1 233  ? 140.526 94.831  98.366  1.00 11.11  ? 233  THR   C CA    1 
ATOM   637  C C     . THR   A 1 233  ? 139.600 94.273  99.438  1.00 13.43  ? 233  THR   C C     1 
ATOM   638  O O     . THR   A 1 233  ? 138.425 94.632  99.495  1.00 18.12  ? 233  THR   C O     1 
ATOM   639  C CB    . THR   A 1 233  ? 140.420 93.984  97.086  1.00 12.59  ? 233  THR   C CB    1 
ATOM   640  O OG1   . THR   A 1 233  ? 139.095 94.045  96.579  1.00 16.80  ? 233  THR   C OG1   1 
ATOM   641  C CG2   . THR   A 1 233  ? 140.769 92.559  97.354  1.00 17.01  ? 233  THR   C CG2   1 
ATOM   642  N N     . ILE   A 1 234  ? 140.114 93.400  100.299 1.00 13.68  ? 234  ILE   C N     1 
ATOM   643  C CA    . ILE   A 1 234  ? 139.263 92.834  101.331 1.00 11.59  ? 234  ILE   C CA    1 
ATOM   644  C C     . ILE   A 1 234  ? 138.938 93.912  102.335 1.00 13.69  ? 234  ILE   C C     1 
ATOM   645  O O     . ILE   A 1 234  ? 137.808 94.008  102.807 1.00 18.31  ? 234  ILE   C O     1 
ATOM   646  C CB    . ILE   A 1 234  ? 139.892 91.626  102.036 1.00 10.58  ? 234  ILE   C CB    1 
ATOM   647  C CG1   . ILE   A 1 234  ? 140.174 90.514  101.036 1.00 13.91  ? 234  ILE   C CG1   1 
ATOM   648  C CG2   . ILE   A 1 234  ? 138.979 91.122  103.134 1.00 12.92  ? 234  ILE   C CG2   1 
ATOM   649  C CD1   . ILE   A 1 234  ? 139.014 90.148  100.135 1.00 17.47  ? 234  ILE   C CD1   1 
ATOM   650  N N     . LEU   A 1 235  ? 139.928 94.734  102.650 1.00 13.98  ? 235  LEU   C N     1 
ATOM   651  C CA    . LEU   A 1 235  ? 139.705 95.851  103.544 1.00 11.63  ? 235  LEU   C CA    1 
ATOM   652  C C     . LEU   A 1 235  ? 138.644 96.782  102.961 1.00 12.84  ? 235  LEU   C C     1 
ATOM   653  O O     . LEU   A 1 235  ? 137.763 97.249  103.684 1.00 16.31  ? 235  LEU   C O     1 
ATOM   654  C CB    . LEU   A 1 235  ? 141.017 96.609  103.761 1.00 11.68  ? 235  LEU   C CB    1 
ATOM   655  C CG    . LEU   A 1 235  ? 140.972 97.818  104.694 1.00 12.64  ? 235  LEU   C CG    1 
ATOM   656  C CD1   . LEU   A 1 235  ? 140.587 97.388  106.101 1.00 18.12  ? 235  LEU   C CD1   1 
ATOM   657  C CD2   . LEU   A 1 235  ? 142.328 98.472  104.692 1.00 14.38  ? 235  LEU   C CD2   1 
ATOM   658  N N     . ALA   A 1 236  ? 138.715 97.045  101.655 1.00 12.77  ? 236  ALA   C N     1 
ATOM   659  C CA    . ALA   A 1 236  ? 137.728 97.899  101.000 1.00 10.91  ? 236  ALA   C CA    1 
ATOM   660  C C     . ALA   A 1 236  ? 136.325 97.292  101.077 1.00 11.45  ? 236  ALA   C C     1 
ATOM   661  O O     . ALA   A 1 236  ? 135.351 97.996  101.339 1.00 15.01  ? 236  ALA   C O     1 
ATOM   662  C CB    . ALA   A 1 236  ? 138.113 98.135  99.551  1.00 12.09  ? 236  ALA   C CB    1 
ATOM   663  N N     . ARG   A 1 237  ? 136.228 95.977  100.882 1.00 11.59  ? 237  ARG   C N     1 
ATOM   664  C CA    . ARG   A 1 237  ? 134.937 95.303  100.980 1.00 9.90   ? 237  ARG   C CA    1 
ATOM   665  C C     . ARG   A 1 237  ? 134.418 95.314  102.412 1.00 12.39  ? 237  ARG   C C     1 
ATOM   666  O O     . ARG   A 1 237  ? 133.215 95.453  102.642 1.00 13.69  ? 237  ARG   C O     1 
ATOM   667  C CB    . ARG   A 1 237  ? 135.029 93.875  100.474 1.00 11.10  ? 237  ARG   C CB    1 
ATOM   668  C CG    . ARG   A 1 237  ? 135.177 93.759  98.970  1.00 14.30  ? 237  ARG   C CG    1 
ATOM   669  C CD    . ARG   A 1 237  ? 135.323 92.354  98.516  1.00 18.10  ? 237  ARG   C CD    1 
ATOM   670  N NE    . ARG   A 1 237  ? 135.480 92.290  97.070  1.00 26.65  ? 237  ARG   C NE    1 
ATOM   671  C CZ    . ARG   A 1 237  ? 135.821 91.190  96.361  1.00 39.41  ? 237  ARG   C CZ    1 
ATOM   672  N NH1   . ARG   A 1 237  ? 136.044 90.040  96.953  1.00 45.74  ? 237  ARG   C NH1   1 
ATOM   673  N NH2   . ARG   A 1 237  ? 135.931 91.269  95.046  1.00 42.05  ? 237  ARG   C NH2   1 
ATOM   674  N N     . LYS   A 1 238  ? 135.323 95.193  103.379 1.00 13.65  ? 238  LYS   C N     1 
ATOM   675  C CA    . LYS   A 1 238  ? 134.928 95.233  104.777 1.00 10.19  ? 238  LYS   C CA    1 
ATOM   676  C C     . LYS   A 1 238  ? 134.333 96.591  105.111 1.00 12.24  ? 238  LYS   C C     1 
ATOM   677  O O     . LYS   A 1 238  ? 133.309 96.672  105.787 1.00 16.51  ? 238  LYS   C O     1 
ATOM   678  C CB    . LYS   A 1 238  ? 136.115 94.944  105.693 1.00 13.43  ? 238  LYS   C CB    1 
ATOM   679  C CG    . LYS   A 1 238  ? 135.776 94.881  107.180 1.00 15.53  ? 238  LYS   C CG    1 
ATOM   680  C CD    . LYS   A 1 238  ? 134.856 93.696  107.491 1.00 21.88  ? 238  LYS   C CD    1 
ATOM   681  C CE    . LYS   A 1 238  ? 134.820 93.373  108.984 1.00 27.84  ? 238  LYS   C CE    1 
ATOM   682  N NZ    . LYS   A 1 238  ? 134.107 94.413  109.782 1.00 23.91  ? 238  LYS   C NZ    1 
ATOM   683  N N     . MET   A 1 239  ? 134.952 97.659  104.610 1.00 12.30  ? 239  MET   C N     1 
ATOM   684  C CA    . MET   A 1 239  ? 134.442 99.000  104.861 1.00 9.36   ? 239  MET   C CA    1 
ATOM   685  C C     . MET   A 1 239  ? 133.032 99.169  104.313 1.00 10.59  ? 239  MET   C C     1 
ATOM   686  O O     . MET   A 1 239  ? 132.180 99.775  104.962 1.00 12.29  ? 239  MET   C O     1 
ATOM   687  C CB    . MET   A 1 239  ? 135.369 100.052 104.263 1.00 9.78   ? 239  MET   C CB    1 
ATOM   688  C CG    . MET   A 1 239  ? 136.703 100.164 104.970 1.00 11.19  ? 239  MET   C CG    1 
ATOM   689  S SD    . MET   A 1 239  ? 137.844 101.302 104.183 1.00 12.40  ? 239  MET   C SD    1 
ATOM   690  C CE    . MET   A 1 239  ? 137.173 102.882 104.685 1.00 15.62  ? 239  MET   C CE    1 
ATOM   691  N N     . MET   A 1 240  ? 132.773 98.618  103.129 1.00 11.35  ? 240  MET   C N     1 
ATOM   692  C CA    . MET   A 1 240  ? 131.441 98.712  102.539 1.00 9.40   ? 240  MET   C CA    1 
ATOM   693  C C     . MET   A 1 240  ? 130.395 98.065  103.430 1.00 9.30   ? 240  MET   C C     1 
ATOM   694  O O     . MET   A 1 240  ? 129.305 98.609  103.620 1.00 11.59  ? 240  MET   C O     1 
ATOM   695  C CB    . MET   A 1 240  ? 131.416 98.047  101.167 1.00 11.05  ? 240  MET   C CB    1 
ATOM   696  C CG    . MET   A 1 240  ? 132.119 98.811  100.079 1.00 10.19  ? 240  MET   C CG    1 
ATOM   697  S SD    . MET   A 1 240  ? 131.349 100.387 99.733  1.00 11.59  ? 240  MET   C SD    1 
ATOM   698  C CE    . MET   A 1 240  ? 129.776 99.890  99.036  1.00 12.04  ? 240  MET   C CE    1 
ATOM   699  N N     . LEU   A 1 241  ? 130.727 96.903  103.980 1.00 10.52  ? 241  LEU   C N     1 
ATOM   700  C CA    . LEU   A 1 241  ? 129.795 96.188  104.837 1.00 9.22   ? 241  LEU   C CA    1 
ATOM   701  C C     . LEU   A 1 241  ? 129.610 96.869  106.189 1.00 12.16  ? 241  LEU   C C     1 
ATOM   702  O O     . LEU   A 1 241  ? 128.483 97.007  106.663 1.00 15.63  ? 241  LEU   C O     1 
ATOM   703  C CB    . LEU   A 1 241  ? 130.263 94.747  105.042 1.00 9.45   ? 241  LEU   C CB    1 
ATOM   704  C CG    . LEU   A 1 241  ? 129.383 93.868  105.946 1.00 10.56  ? 241  LEU   C CG    1 
ATOM   705  C CD1   . LEU   A 1 241  ? 127.973 93.788  105.378 1.00 15.98  ? 241  LEU   C CD1   1 
ATOM   706  C CD2   . LEU   A 1 241  ? 130.001 92.478  106.042 1.00 22.94  ? 241  LEU   C CD2   1 
ATOM   707  N N     . ASP   A 1 242  ? 130.703 97.301  106.816 1.00 11.34  ? 242  ASP   C N     1 
ATOM   708  C CA    . ASP   A 1 242  ? 130.594 97.928  108.129 1.00 9.28   ? 242  ASP   C CA    1 
ATOM   709  C C     . ASP   A 1 242  ? 129.784 99.211  108.052 1.00 10.88  ? 242  ASP   C C     1 
ATOM   710  O O     . ASP   A 1 242  ? 129.039 99.551  108.976 1.00 13.46  ? 242  ASP   C O     1 
ATOM   711  C CB    . ASP   A 1 242  ? 131.970 98.219  108.720 1.00 9.83   ? 242  ASP   C CB    1 
ATOM   712  C CG    . ASP   A 1 242  ? 132.682 96.982  109.193 1.00 13.89  ? 242  ASP   C CG    1 
ATOM   713  O OD1   . ASP   A 1 242  ? 132.060 95.951  109.299 1.00 13.97  ? 242  ASP   C OD1   1 
ATOM   714  O OD2   . ASP   A 1 242  ? 133.857 97.058  109.465 1.00 18.49  ? 242  ASP   C OD2   1 
ATOM   715  N N     . TRP   A 1 243  ? 129.919 99.930  106.948 1.00 10.87  ? 243  TRP   C N     1 
ATOM   716  C CA    . TRP   A 1 243  ? 129.119 101.121 106.742 1.00 9.55   ? 243  TRP   C CA    1 
ATOM   717  C C     . TRP   A 1 243  ? 127.647 100.785 106.582 1.00 10.71  ? 243  TRP   C C     1 
ATOM   718  O O     . TRP   A 1 243  ? 126.788 101.385 107.222 1.00 15.03  ? 243  TRP   C O     1 
ATOM   719  C CB    . TRP   A 1 243  ? 129.601 101.892 105.534 1.00 9.35   ? 243  TRP   C CB    1 
ATOM   720  C CG    . TRP   A 1 243  ? 128.671 102.969 105.131 1.00 8.87   ? 243  TRP   C CG    1 
ATOM   721  C CD1   . TRP   A 1 243  ? 128.589 104.220 105.642 1.00 10.07  ? 243  TRP   C CD1   1 
ATOM   722  C CD2   . TRP   A 1 243  ? 127.658 102.889 104.118 1.00 9.59   ? 243  TRP   C CD2   1 
ATOM   723  N NE1   . TRP   A 1 243  ? 127.598 104.916 105.019 1.00 10.98  ? 243  TRP   C NE1   1 
ATOM   724  C CE2   . TRP   A 1 243  ? 127.027 104.119 104.080 1.00 10.21  ? 243  TRP   C CE2   1 
ATOM   725  C CE3   . TRP   A 1 243  ? 127.258 101.888 103.232 1.00 10.30  ? 243  TRP   C CE3   1 
ATOM   726  C CZ2   . TRP   A 1 243  ? 125.996 104.372 103.228 1.00 10.67  ? 243  TRP   C CZ2   1 
ATOM   727  C CZ3   . TRP   A 1 243  ? 126.221 102.149 102.366 1.00 9.65   ? 243  TRP   C CZ3   1 
ATOM   728  C CH2   . TRP   A 1 243  ? 125.610 103.364 102.362 1.00 9.96   ? 243  TRP   C CH2   1 
ATOM   729  N N     . ALA   A 1 244  ? 127.348 99.814  105.727 1.00 10.72  ? 244  ALA   C N     1 
ATOM   730  C CA    . ALA   A 1 244  ? 125.962 99.455  105.456 1.00 10.72  ? 244  ALA   C CA    1 
ATOM   731  C C     . ALA   A 1 244  ? 125.267 98.963  106.720 1.00 11.68  ? 244  ALA   C C     1 
ATOM   732  O O     . ALA   A 1 244  ? 124.062 99.165  106.895 1.00 15.43  ? 244  ALA   C O     1 
ATOM   733  C CB    . ALA   A 1 244  ? 125.908 98.415  104.363 1.00 12.64  ? 244  ALA   C CB    1 
ATOM   734  N N     . SER   A 1 245  ? 126.031 98.347  107.619 1.00 11.39  ? 245  SER   C N     1 
ATOM   735  C CA    . SER   A 1 245  ? 125.506 97.862  108.890 1.00 10.52  ? 245  SER   C CA    1 
ATOM   736  C C     . SER   A 1 245  ? 125.351 98.984  109.917 1.00 12.68  ? 245  SER   C C     1 
ATOM   737  O O     . SER   A 1 245  ? 124.805 98.769  110.999 1.00 16.62  ? 245  SER   C O     1 
ATOM   738  C CB    . SER   A 1 245  ? 126.401 96.775  109.450 1.00 11.82  ? 245  SER   C CB    1 
ATOM   739  O OG    . SER   A 1 245  ? 126.382 95.631  108.638 1.00 11.48  ? 245  SER   C OG    1 
ATOM   740  N N     . GLY   A 1 246  ? 125.831 100.181 109.579 1.00 12.15  ? 246  GLY   C N     1 
ATOM   741  C CA    . GLY   A 1 246  ? 125.699 101.352 110.439 1.00 11.43  ? 246  GLY   C CA    1 
ATOM   742  C C     . GLY   A 1 246  ? 126.728 101.458 111.563 1.00 12.31  ? 246  GLY   C C     1 
ATOM   743  O O     . GLY   A 1 246  ? 126.459 102.106 112.575 1.00 14.97  ? 246  GLY   C O     1 
ATOM   744  N N     . THR   A 1 247  ? 127.900 100.841 111.407 1.00 11.08  ? 247  THR   C N     1 
ATOM   745  C CA    . THR   A 1 247  ? 128.909 100.930 112.460 1.00 9.17   ? 247  THR   C CA    1 
ATOM   746  C C     . THR   A 1 247  ? 130.088 101.809 112.049 1.00 10.14  ? 247  THR   C C     1 
ATOM   747  O O     . THR   A 1 247  ? 130.798 102.350 112.898 1.00 13.84  ? 247  THR   C O     1 
ATOM   748  C CB    . THR   A 1 247  ? 129.431 99.536  112.837 1.00 9.73   ? 247  THR   C CB    1 
ATOM   749  O OG1   . THR   A 1 247  ? 130.094 98.961  111.711 1.00 13.36  ? 247  THR   C OG1   1 
ATOM   750  C CG2   . THR   A 1 247  ? 128.276 98.641  113.242 1.00 13.58  ? 247  THR   C CG2   1 
ATOM   751  N N     . LEU   A 1 248  ? 130.291 101.959 110.745 1.00 11.11  ? 248  LEU   C N     1 
ATOM   752  C CA    . LEU   A 1 248  ? 131.405 102.740 110.217 1.00 8.77   ? 248  LEU   C CA    1 
ATOM   753  C C     . LEU   A 1 248  ? 130.909 103.916 109.378 1.00 10.32  ? 248  LEU   C C     1 
ATOM   754  O O     . LEU   A 1 248  ? 130.150 103.733 108.431 1.00 13.12  ? 248  LEU   C O     1 
ATOM   755  C CB    . LEU   A 1 248  ? 132.306 101.822 109.378 1.00 9.63   ? 248  LEU   C CB    1 
ATOM   756  C CG    . LEU   A 1 248  ? 133.472 102.471 108.651 1.00 9.83   ? 248  LEU   C CG    1 
ATOM   757  C CD1   . LEU   A 1 248  ? 134.491 102.995 109.649 1.00 17.61  ? 248  LEU   C CD1   1 
ATOM   758  C CD2   . LEU   A 1 248  ? 134.103 101.458 107.722 1.00 11.99  ? 248  LEU   C CD2   1 
ATOM   759  N N     . TYR   A 1 249  ? 131.335 105.126 109.732 1.00 10.64  ? 249  TYR   C N     1 
ATOM   760  C CA    . TYR   A 1 249  ? 130.917 106.341 109.026 1.00 8.94   ? 249  TYR   C CA    1 
ATOM   761  C C     . TYR   A 1 249  ? 129.404 106.432 108.889 1.00 11.45  ? 249  TYR   C C     1 
ATOM   762  O O     . TYR   A 1 249  ? 128.895 106.753 107.816 1.00 14.27  ? 249  TYR   C O     1 
ATOM   763  C CB    . TYR   A 1 249  ? 131.517 106.424 107.620 1.00 9.18   ? 249  TYR   C CB    1 
ATOM   764  C CG    . TYR   A 1 249  ? 133.005 106.459 107.539 1.00 9.03   ? 249  TYR   C CG    1 
ATOM   765  C CD1   . TYR   A 1 249  ? 133.676 105.456 106.876 1.00 9.42   ? 249  TYR   C CD1   1 
ATOM   766  C CD2   . TYR   A 1 249  ? 133.699 107.487 108.115 1.00 12.18  ? 249  TYR   C CD2   1 
ATOM   767  C CE1   . TYR   A 1 249  ? 135.040 105.476 106.798 1.00 9.33   ? 249  TYR   C CE1   1 
ATOM   768  C CE2   . TYR   A 1 249  ? 135.066 107.514 108.033 1.00 15.34  ? 249  TYR   C CE2   1 
ATOM   769  C CZ    . TYR   A 1 249  ? 135.734 106.508 107.379 1.00 13.89  ? 249  TYR   C CZ    1 
ATOM   770  O OH    . TYR   A 1 249  ? 137.096 106.537 107.298 1.00 19.76  ? 249  TYR   C OH    1 
ATOM   771  N N     . GLN   A 1 250  ? 128.683 106.148 109.964 1.00 13.07  ? 250  GLN   C N     1 
ATOM   772  C CA    . GLN   A 1 250  ? 127.226 106.130 109.918 1.00 13.14  ? 250  GLN   C CA    1 
ATOM   773  C C     . GLN   A 1 250  ? 126.607 107.528 109.873 1.00 15.41  ? 250  GLN   C C     1 
ATOM   774  O O     . GLN   A 1 250  ? 125.407 107.670 109.645 1.00 17.10  ? 250  GLN   C O     1 
ATOM   775  C CB    . GLN   A 1 250  ? 126.666 105.354 111.118 1.00 11.95  ? 250  GLN   C CB    1 
ATOM   776  C CG    . GLN   A 1 250  ? 126.762 106.075 112.458 1.00 12.63  ? 250  GLN   C CG    1 
ATOM   777  C CD    . GLN   A 1 250  ? 128.087 105.861 113.148 1.00 15.81  ? 250  GLN   C CD    1 
ATOM   778  O OE1   . GLN   A 1 250  ? 129.132 105.729 112.500 1.00 17.92  ? 250  GLN   C OE1   1 
ATOM   779  N NE2   . GLN   A 1 250  ? 128.057 105.828 114.474 1.00 14.17  ? 250  GLN   C NE2   1 
ATOM   780  N N     . ASP   A 1 251  ? 127.412 108.552 110.134 1.00 14.80  ? 251  ASP   C N     1 
ATOM   781  C CA    . ASP   A 1 251  ? 126.918 109.921 110.198 1.00 14.31  ? 251  ASP   C CA    1 
ATOM   782  C C     . ASP   A 1 251  ? 127.219 110.757 108.952 1.00 15.15  ? 251  ASP   C C     1 
ATOM   783  O O     . ASP   A 1 251  ? 126.316 111.374 108.381 1.00 15.43  ? 251  ASP   C O     1 
ATOM   784  C CB    . ASP   A 1 251  ? 127.484 110.601 111.446 1.00 15.08  ? 251  ASP   C CB    1 
ATOM   785  C CG    . ASP   A 1 251  ? 129.000 110.468 111.555 1.00 20.40  ? 251  ASP   C CG    1 
ATOM   786  O OD1   . ASP   A 1 251  ? 129.601 109.884 110.670 1.00 18.99  ? 251  ASP   C OD1   1 
ATOM   787  O OD2   . ASP   A 1 251  ? 129.548 110.947 112.515 1.00 21.24  ? 251  ASP   C OD2   1 
ATOM   788  N N     . ARG   A 1 252  ? 128.494 110.827 108.576 1.00 14.88  ? 252  ARG   C N     1 
ATOM   789  C CA    . ARG   A 1 252  ? 128.954 111.730 107.524 1.00 12.94  ? 252  ARG   C CA    1 
ATOM   790  C C     . ARG   A 1 252  ? 128.675 111.281 106.088 1.00 14.16  ? 252  ARG   C C     1 
ATOM   791  O O     . ARG   A 1 252  ? 128.663 112.117 105.186 1.00 18.82  ? 252  ARG   C O     1 
ATOM   792  C CB    . ARG   A 1 252  ? 130.444 111.998 107.668 1.00 12.99  ? 252  ARG   C CB    1 
ATOM   793  C CG    . ARG   A 1 252  ? 131.346 110.854 107.291 1.00 17.46  ? 252  ARG   C CG    1 
ATOM   794  C CD    . ARG   A 1 252  ? 132.763 111.194 107.501 1.00 14.34  ? 252  ARG   C CD    1 
ATOM   795  N NE    . ARG   A 1 252  ? 133.116 111.194 108.901 1.00 13.50  ? 252  ARG   C NE    1 
ATOM   796  C CZ    . ARG   A 1 252  ? 134.219 111.763 109.408 1.00 20.65  ? 252  ARG   C CZ    1 
ATOM   797  N NH1   . ARG   A 1 252  ? 135.066 112.387 108.628 1.00 26.35  ? 252  ARG   C NH1   1 
ATOM   798  N NH2   . ARG   A 1 252  ? 134.461 111.700 110.702 1.00 35.01  ? 252  ARG   C NH2   1 
ATOM   799  N N     . PHE   A 1 253  ? 128.502 109.981 105.843 1.00 12.11  ? 253  PHE   C N     1 
ATOM   800  C CA    . PHE   A 1 253  ? 128.289 109.531 104.468 1.00 9.58   ? 253  PHE   C CA    1 
ATOM   801  C C     . PHE   A 1 253  ? 126.921 108.907 104.260 1.00 11.58  ? 253  PHE   C C     1 
ATOM   802  O O     . PHE   A 1 253  ? 126.541 107.965 104.956 1.00 14.56  ? 253  PHE   C O     1 
ATOM   803  C CB    . PHE   A 1 253  ? 129.356 108.519 104.035 1.00 8.65   ? 253  PHE   C CB    1 
ATOM   804  C CG    . PHE   A 1 253  ? 130.759 109.064 103.942 1.00 8.18   ? 253  PHE   C CG    1 
ATOM   805  C CD1   . PHE   A 1 253  ? 131.032 110.251 103.285 1.00 10.05  ? 253  PHE   C CD1   1 
ATOM   806  C CD2   . PHE   A 1 253  ? 131.811 108.373 104.504 1.00 8.31   ? 253  PHE   C CD2   1 
ATOM   807  C CE1   . PHE   A 1 253  ? 132.320 110.734 103.208 1.00 8.65   ? 253  PHE   C CE1   1 
ATOM   808  C CE2   . PHE   A 1 253  ? 133.097 108.855 104.428 1.00 8.46   ? 253  PHE   C CE2   1 
ATOM   809  C CZ    . PHE   A 1 253  ? 133.352 110.036 103.782 1.00 7.41   ? 253  PHE   C CZ    1 
ATOM   810  N N     . ASP   A 1 254  ? 126.201 109.403 103.256 1.00 12.68  ? 254  ASP   C N     1 
ATOM   811  C CA    . ASP   A 1 254  ? 124.904 108.839 102.907 1.00 13.51  ? 254  ASP   C CA    1 
ATOM   812  C C     . ASP   A 1 254  ? 125.069 107.675 101.941 1.00 14.49  ? 254  ASP   C C     1 
ATOM   813  O O     . ASP   A 1 254  ? 124.275 106.735 101.956 1.00 17.50  ? 254  ASP   C O     1 
ATOM   814  C CB    . ASP   A 1 254  ? 123.984 109.886 102.271 1.00 19.56  ? 254  ASP   C CB    1 
ATOM   815  C CG    . ASP   A 1 254  ? 123.526 110.987 103.217 1.00 23.43  ? 254  ASP   C CG    1 
ATOM   816  O OD1   . ASP   A 1 254  ? 123.054 110.690 104.292 1.00 23.21  ? 254  ASP   C OD1   1 
ATOM   817  O OD2   . ASP   A 1 254  ? 123.636 112.129 102.845 1.00 23.07  ? 254  ASP   C OD2   1 
ATOM   818  N N     . TYR   A 1 255  ? 126.094 107.745 101.091 1.00 11.12  ? 255  TYR   C N     1 
ATOM   819  C CA    . TYR   A 1 255  ? 126.352 106.668 100.140 1.00 10.15  ? 255  TYR   C CA    1 
ATOM   820  C C     . TYR   A 1 255  ? 127.826 106.348 99.985  1.00 10.15  ? 255  TYR   C C     1 
ATOM   821  O O     . TYR   A 1 255  ? 128.665 107.248 99.911  1.00 10.91  ? 255  TYR   C O     1 
ATOM   822  C CB    . TYR   A 1 255  ? 125.802 107.006 98.763  1.00 10.79  ? 255  TYR   C CB    1 
ATOM   823  C CG    . TYR   A 1 255  ? 124.355 107.231 98.731  1.00 11.62  ? 255  TYR   C CG    1 
ATOM   824  C CD1   . TYR   A 1 255  ? 123.853 108.473 99.004  1.00 14.96  ? 255  TYR   C CD1   1 
ATOM   825  C CD2   . TYR   A 1 255  ? 123.520 106.190 98.419  1.00 14.30  ? 255  TYR   C CD2   1 
ATOM   826  C CE1   . TYR   A 1 255  ? 122.508 108.678 98.978  1.00 23.16  ? 255  TYR   C CE1   1 
ATOM   827  C CE2   . TYR   A 1 255  ? 122.170 106.382 98.388  1.00 18.28  ? 255  TYR   C CE2   1 
ATOM   828  C CZ    . TYR   A 1 255  ? 121.658 107.623 98.665  1.00 24.17  ? 255  TYR   C CZ    1 
ATOM   829  O OH    . TYR   A 1 255  ? 120.303 107.824 98.637  1.00 26.74  ? 255  TYR   C OH    1 
ATOM   830  N N     . LEU   A 1 256  ? 128.115 105.063 99.841  1.00 11.02  ? 256  LEU   C N     1 
ATOM   831  C CA    . LEU   A 1 256  ? 129.433 104.603 99.441  1.00 1.02   ? 256  LEU   C CA    1 
ATOM   832  C C     . LEU   A 1 256  ? 129.294 103.895 98.114  1.00 12.81  ? 256  LEU   C C     1 
ATOM   833  O O     . LEU   A 1 256  ? 128.527 102.942 98.001  1.00 13.21  ? 256  LEU   C O     1 
ATOM   834  C CB    . LEU   A 1 256  ? 130.038 103.628 100.454 1.00 11.76  ? 256  LEU   C CB    1 
ATOM   835  C CG    . LEU   A 1 256  ? 130.227 104.107 101.880 1.00 10.95  ? 256  LEU   C CG    1 
ATOM   836  C CD1   . LEU   A 1 256  ? 130.906 103.010 102.659 1.00 13.70  ? 256  LEU   C CD1   1 
ATOM   837  C CD2   . LEU   A 1 256  ? 131.035 105.334 101.891 1.00 10.74  ? 256  LEU   C CD2   1 
ATOM   838  N N     . PHE   A 1 257  ? 130.019 104.354 97.110  1.00 12.09  ? 257  PHE   C N     1 
ATOM   839  C CA    . PHE   A 1 257  ? 129.924 103.738 95.797  1.00 0.56   ? 257  PHE   C CA    1 
ATOM   840  C C     . PHE   A 1 257  ? 131.200 102.987 95.477  1.00 0.06   ? 257  PHE   C C     1 
ATOM   841  O O     . PHE   A 1 257  ? 132.267 103.585 95.342  1.00 7.78   ? 257  PHE   C O     1 
ATOM   842  C CB    . PHE   A 1 257  ? 129.629 104.784 94.725  1.00 10.75  ? 257  PHE   C CB    1 
ATOM   843  C CG    . PHE   A 1 257  ? 128.277 105.422 94.876  1.00 9.88   ? 257  PHE   C CG    1 
ATOM   844  C CD1   . PHE   A 1 257  ? 128.151 106.739 95.271  1.00 9.15   ? 257  PHE   C CD1   1 
ATOM   845  C CD2   . PHE   A 1 257  ? 127.127 104.694 94.637  1.00 11.85  ? 257  PHE   C CD2   1 
ATOM   846  C CE1   . PHE   A 1 257  ? 126.905 107.308 95.414  1.00 9.56   ? 257  PHE   C CE1   1 
ATOM   847  C CE2   . PHE   A 1 257  ? 125.888 105.260 94.781  1.00 10.53  ? 257  PHE   C CE2   1 
ATOM   848  C CZ    . PHE   A 1 257  ? 125.776 106.564 95.168  1.00 9.29   ? 257  PHE   C CZ    1 
ATOM   849  N N     . TYR   A 1 258  ? 131.094 101.670 95.382  1.00 14.49  ? 258  TYR   C N     1 
ATOM   850  C CA    . TYR   A 1 258  ? 132.265 100.835 95.163  1.00 6.60   ? 258  TYR   C CA    1 
ATOM   851  C C     . TYR   A 1 258  ? 132.576 100.685 93.683  1.00 13.09  ? 258  TYR   C C     1 
ATOM   852  O O     . TYR   A 1 258  ? 131.739 100.223 92.906  1.00 18.21  ? 258  TYR   C O     1 
ATOM   853  C CB    . TYR   A 1 258  ? 132.046 99.467  95.803  1.00 10.45  ? 258  TYR   C CB    1 
ATOM   854  C CG    . TYR   A 1 258  ? 133.188 98.515  95.645  1.00 9.54   ? 258  TYR   C CG    1 
ATOM   855  C CD1   . TYR   A 1 258  ? 134.335 98.677  96.391  1.00 9.41   ? 258  TYR   C CD1   1 
ATOM   856  C CD2   . TYR   A 1 258  ? 133.082 97.472  94.757  1.00 12.34  ? 258  TYR   C CD2   1 
ATOM   857  C CE1   . TYR   A 1 258  ? 135.374 97.789  96.244  1.00 9.44   ? 258  TYR   C CE1   1 
ATOM   858  C CE2   . TYR   A 1 258  ? 134.114 96.586  94.612  1.00 12.38  ? 258  TYR   C CE2   1 
ATOM   859  C CZ    . TYR   A 1 258  ? 135.256 96.742  95.346  1.00 10.93  ? 258  TYR   C CZ    1 
ATOM   860  O OH    . TYR   A 1 258  ? 136.282 95.849  95.192  1.00 15.82  ? 258  TYR   C OH    1 
ATOM   861  N N     . ILE   A 1 259  ? 133.785 101.076 93.301  1.00 12.47  ? 259  ILE   C N     1 
ATOM   862  C CA    . ILE   A 1 259  ? 134.237 100.994 91.921  1.00 12.54  ? 259  ILE   C CA    1 
ATOM   863  C C     . ILE   A 1 259  ? 135.322 99.941  91.789  1.00 14.19  ? 259  ILE   C C     1 
ATOM   864  O O     . ILE   A 1 259  ? 136.379 100.043 92.412  1.00 17.08  ? 259  ILE   C O     1 
ATOM   865  C CB    . ILE   A 1 259  ? 134.781 102.352 91.436  1.00 13.06  ? 259  ILE   C CB    1 
ATOM   866  C CG1   . ILE   A 1 259  ? 133.672 103.414 91.497  1.00 14.17  ? 259  ILE   C CG1   1 
ATOM   867  C CG2   . ILE   A 1 259  ? 135.350 102.218 90.022  1.00 18.70  ? 259  ILE   C CG2   1 
ATOM   868  C CD1   . ILE   A 1 259  ? 134.170 104.838 91.307  1.00 16.70  ? 259  ILE   C CD1   1 
ATOM   869  N N     . HIS   A 1 260  ? 135.069 98.930  90.974  1.00 15.35  ? 260  HIS   C N     1 
ATOM   870  C CA    . HIS   A 1 260  ? 136.047 97.871  90.798  1.00 15.60  ? 260  HIS   C CA    1 
ATOM   871  C C     . HIS   A 1 260  ? 136.814 98.139  89.514  1.00 20.84  ? 260  HIS   C C     1 
ATOM   872  O O     . HIS   A 1 260  ? 136.260 98.026  88.423  1.00 24.75  ? 260  HIS   C O     1 
ATOM   873  C CB    . HIS   A 1 260  ? 135.352 96.505  90.752  1.00 18.94  ? 260  HIS   C CB    1 
ATOM   874  C CG    . HIS   A 1 260  ? 136.274 95.333  90.883  1.00 22.48  ? 260  HIS   C CG    1 
ATOM   875  N ND1   . HIS   A 1 260  ? 135.931 94.067  90.452  1.00 28.48  ? 260  HIS   C ND1   1 
ATOM   876  C CD2   . HIS   A 1 260  ? 137.513 95.225  91.417  1.00 20.03  ? 260  HIS   C CD2   1 
ATOM   877  C CE1   . HIS   A 1 260  ? 136.924 93.235  90.709  1.00 31.40  ? 260  HIS   C CE1   1 
ATOM   878  N NE2   . HIS   A 1 260  ? 137.892 93.913  91.296  1.00 23.46  ? 260  HIS   C NE2   1 
ATOM   879  N N     . CYS   A 1 261  ? 138.075 98.541  89.642  1.00 19.85  ? 261  CYS   C N     1 
ATOM   880  C CA    . CYS   A 1 261  ? 138.854 98.997  88.494  1.00 18.80  ? 261  CYS   C CA    1 
ATOM   881  C C     . CYS   A 1 261  ? 139.077 97.907  87.460  1.00 21.98  ? 261  CYS   C C     1 
ATOM   882  O O     . CYS   A 1 261  ? 139.173 98.183  86.267  1.00 24.71  ? 261  CYS   C O     1 
ATOM   883  C CB    . CYS   A 1 261  ? 140.194 99.546  88.950  1.00 17.69  ? 261  CYS   C CB    1 
ATOM   884  S SG    . CYS   A 1 261  ? 140.076 101.120 89.816  1.00 20.48  ? 261  CYS   C SG    1 
ATOM   885  N N     . ARG   A 1 262  ? 139.104 96.663  87.905  1.00 22.17  ? 262  ARG   C N     1 
ATOM   886  C CA    . ARG   A 1 262  ? 139.275 95.529  87.009  1.00 21.09  ? 262  ARG   C CA    1 
ATOM   887  C C     . ARG   A 1 262  ? 138.185 95.500  85.941  1.00 24.00  ? 262  ARG   C C     1 
ATOM   888  O O     . ARG   A 1 262  ? 138.381 94.949  84.857  1.00 28.96  ? 262  ARG   C O     1 
ATOM   889  C CB    . ARG   A 1 262  ? 139.242 94.232  87.800  1.00 23.98  ? 262  ARG   C CB    1 
ATOM   890  C CG    . ARG   A 1 262  ? 139.496 92.975  87.002  1.00 27.89  ? 262  ARG   C CG    1 
ATOM   891  C CD    . ARG   A 1 262  ? 139.462 91.769  87.865  1.00 28.37  ? 262  ARG   C CD    1 
ATOM   892  N NE    . ARG   A 1 262  ? 140.547 91.767  88.837  1.00 31.11  ? 262  ARG   C NE    1 
ATOM   893  C CZ    . ARG   A 1 262  ? 140.851 90.748  89.660  1.00 37.19  ? 262  ARG   C CZ    1 
ATOM   894  N NH1   . ARG   A 1 262  ? 140.158 89.631  89.634  1.00 37.70  ? 262  ARG   C NH1   1 
ATOM   895  N NH2   . ARG   A 1 262  ? 141.860 90.886  90.496  1.00 38.18  ? 262  ARG   C NH2   1 
ATOM   896  N N     . GLU   A 1 263  ? 137.020 96.056  86.270  1.00 26.17  ? 263  GLU   C N     1 
ATOM   897  C CA    . GLU   A 1 263  ? 135.858 96.032  85.394  1.00 27.34  ? 263  GLU   C CA    1 
ATOM   898  C C     . GLU   A 1 263  ? 135.674 97.346  84.634  1.00 28.18  ? 263  GLU   C C     1 
ATOM   899  O O     . GLU   A 1 263  ? 134.671 97.531  83.941  1.00 31.79  ? 263  GLU   C O     1 
ATOM   900  C CB    . GLU   A 1 263  ? 134.605 95.727  86.220  1.00 27.22  ? 263  GLU   C CB    1 
ATOM   901  C CG    . GLU   A 1 263  ? 134.642 94.373  86.936  1.00 29.96  ? 263  GLU   C CG    1 
ATOM   902  C CD    . GLU   A 1 263  ? 133.418 94.102  87.776  1.00 33.49  ? 263  GLU   C CD    1 
ATOM   903  O OE1   . GLU   A 1 263  ? 132.332 94.310  87.292  1.00 39.68  ? 263  GLU   C OE1   1 
ATOM   904  O OE2   . GLU   A 1 263  ? 133.572 93.696  88.909  1.00 28.79  ? 263  GLU   C OE2   1 
ATOM   905  N N     . VAL   A 1 264  ? 136.627 98.265  84.775  1.00 27.67  ? 264  VAL   C N     1 
ATOM   906  C CA    . VAL   A 1 264  ? 136.538 99.565  84.120  1.00 26.62  ? 264  VAL   C CA    1 
ATOM   907  C C     . VAL   A 1 264  ? 137.432 99.641  82.894  1.00 30.96  ? 264  VAL   C C     1 
ATOM   908  O O     . VAL   A 1 264  ? 138.641 99.437  82.982  1.00 31.12  ? 264  VAL   C O     1 
ATOM   909  C CB    . VAL   A 1 264  ? 136.922 100.694 85.095  1.00 26.48  ? 264  VAL   C CB    1 
ATOM   910  C CG1   . VAL   A 1 264  ? 136.907 102.032 84.381  1.00 28.21  ? 264  VAL   C CG1   1 
ATOM   911  C CG2   . VAL   A 1 264  ? 135.946 100.712 86.248  1.00 26.45  ? 264  VAL   C CG2   1 
ATOM   912  N N     . SER   A 1 265  ? 136.830 99.953  81.754  1.00 34.90  ? 265  SER   C N     1 
ATOM   913  C CA    . SER   A 1 265  ? 137.570 100.073 80.506  1.00 37.17  ? 265  SER   C CA    1 
ATOM   914  C C     . SER   A 1 265  ? 138.102 101.481 80.310  1.00 39.52  ? 265  SER   C C     1 
ATOM   915  O O     . SER   A 1 265  ? 137.444 102.460 80.660  1.00 40.21  ? 265  SER   C O     1 
ATOM   916  C CB    . SER   A 1 265  ? 136.697 99.697  79.330  1.00 41.86  ? 265  SER   C CB    1 
ATOM   917  O OG    . SER   A 1 265  ? 137.355 99.962  78.120  1.00 45.87  ? 265  SER   C OG    1 
ATOM   918  N N     . LEU   A 1 266  ? 139.284 101.577 79.714  1.00 39.31  ? 266  LEU   C N     1 
ATOM   919  C CA    . LEU   A 1 266  ? 139.895 102.859 79.387  1.00 39.42  ? 266  LEU   C CA    1 
ATOM   920  C C     . LEU   A 1 266  ? 139.719 103.173 77.907  1.00 43.83  ? 266  LEU   C C     1 
ATOM   921  O O     . LEU   A 1 266  ? 140.349 104.086 77.377  1.00 45.37  ? 266  LEU   C O     1 
ATOM   922  C CB    . LEU   A 1 266  ? 141.392 102.840 79.725  1.00 33.90  ? 266  LEU   C CB    1 
ATOM   923  C CG    . LEU   A 1 266  ? 141.767 102.581 81.198  1.00 30.11  ? 266  LEU   C CG    1 
ATOM   924  C CD1   . LEU   A 1 266  ? 143.288 102.526 81.311  1.00 32.30  ? 266  LEU   C CD1   1 
ATOM   925  C CD2   . LEU   A 1 266  ? 141.204 103.682 82.080  1.00 30.53  ? 266  LEU   C CD2   1 
ATOM   926  N N     . VAL   A 1 267  ? 138.893 102.379 77.235  1.00 45.34  ? 267  VAL   C N     1 
ATOM   927  C CA    . VAL   A 1 267  ? 138.679 102.523 75.800  1.00 47.63  ? 267  VAL   C CA    1 
ATOM   928  C C     . VAL   A 1 267  ? 137.317 103.119 75.461  1.00 48.48  ? 267  VAL   C C     1 
ATOM   929  O O     . VAL   A 1 267  ? 137.195 103.903 74.519  1.00 49.62  ? 267  VAL   C O     1 
ATOM   930  C CB    . VAL   A 1 267  ? 138.829 101.157 75.105  1.00 50.25  ? 267  VAL   C CB    1 
ATOM   931  C CG1   . VAL   A 1 267  ? 138.509 101.280 73.618  1.00 52.50  ? 267  VAL   C CG1   1 
ATOM   932  C CG2   . VAL   A 1 267  ? 140.247 100.653 75.307  1.00 53.94  ? 267  VAL   C CG2   1 
ATOM   933  N N     . THR   A 1 268  ? 136.287 102.690 76.179  1.00 48.02  ? 268  THR   C N     1 
ATOM   934  C CA    . THR   A 1 268  ? 134.918 103.071 75.866  1.00 49.81  ? 268  THR   C CA    1 
ATOM   935  C C     . THR   A 1 268  ? 134.555 104.453 76.392  1.00 49.12  ? 268  THR   C C     1 
ATOM   936  O O     . THR   A 1 268  ? 135.271 105.036 77.210  1.00 47.72  ? 268  THR   C O     1 
ATOM   937  C CB    . THR   A 1 268  ? 133.929 102.038 76.430  1.00 45.67  ? 268  THR   C CB    1 
ATOM   938  O OG1   . THR   A 1 268  ? 134.061 101.980 77.856  1.00 46.22  ? 268  THR   C OG1   1 
ATOM   939  C CG2   . THR   A 1 268  ? 134.216 100.666 75.843  1.00 49.25  ? 268  THR   C CG2   1 
ATOM   940  N N     . GLN   A 1 269  ? 133.423 104.966 75.911  1.00 50.55  ? 269  GLN   C N     1 
ATOM   941  C CA    . GLN   A 1 269  ? 132.904 106.268 76.310  1.00 52.42  ? 269  GLN   C CA    1 
ATOM   942  C C     . GLN   A 1 269  ? 131.657 106.135 77.174  1.00 50.26  ? 269  GLN   C C     1 
ATOM   943  O O     . GLN   A 1 269  ? 130.698 105.465 76.787  1.00 49.68  ? 269  GLN   C O     1 
ATOM   944  C CB    . GLN   A 1 269  ? 132.575 107.101 75.067  1.00 55.69  ? 269  GLN   C CB    1 
ATOM   945  C CG    . GLN   A 1 269  ? 132.020 108.474 75.361  1.00 57.36  ? 269  GLN   C CG    1 
ATOM   946  C CD    . GLN   A 1 269  ? 131.707 109.256 74.118  1.00 63.07  ? 269  GLN   C CD    1 
ATOM   947  O OE1   . GLN   A 1 269  ? 131.662 108.696 73.020  1.00 73.33  ? 269  GLN   C OE1   1 
ATOM   948  N NE2   . GLN   A 1 269  ? 131.485 110.559 74.267  1.00 66.97  ? 269  GLN   C NE2   1 
ATOM   949  N N     . ARG   A 1 270  ? 131.664 106.779 78.338  1.00 47.29  ? 270  ARG   C N     1 
ATOM   950  C CA    . ARG   A 1 270  ? 130.507 106.739 79.225  1.00 44.33  ? 270  ARG   C CA    1 
ATOM   951  C C     . ARG   A 1 270  ? 130.405 107.970 80.117  1.00 44.68  ? 270  ARG   C C     1 
ATOM   952  O O     . ARG   A 1 270  ? 131.403 108.622 80.421  1.00 45.60  ? 270  ARG   C O     1 
ATOM   953  C CB    . ARG   A 1 270  ? 130.537 105.485 80.088  1.00 37.30  ? 270  ARG   C CB    1 
ATOM   954  C CG    . ARG   A 1 270  ? 131.700 105.381 81.069  1.00 40.26  ? 270  ARG   C CG    1 
ATOM   955  C CD    . ARG   A 1 270  ? 131.656 104.091 81.823  1.00 35.58  ? 270  ARG   C CD    1 
ATOM   956  N NE    . ARG   A 1 270  ? 132.814 103.915 82.700  1.00 33.47  ? 270  ARG   C NE    1 
ATOM   957  C CZ    . ARG   A 1 270  ? 132.889 104.311 83.993  1.00 37.50  ? 270  ARG   C CZ    1 
ATOM   958  N NH1   . ARG   A 1 270  ? 131.876 104.909 84.576  1.00 34.96  ? 270  ARG   C NH1   1 
ATOM   959  N NH2   . ARG   A 1 270  ? 133.992 104.099 84.681  1.00 40.24  ? 270  ARG   C NH2   1 
ATOM   960  N N     . SER   A 1 271  ? 129.187 108.257 80.559  1.00 43.07  ? 271  SER   C N     1 
ATOM   961  C CA    . SER   A 1 271  ? 128.908 109.304 81.533  1.00 40.27  ? 271  SER   C CA    1 
ATOM   962  C C     . SER   A 1 271  ? 129.152 108.749 82.915  1.00 35.50  ? 271  SER   C C     1 
ATOM   963  O O     . SER   A 1 271  ? 129.551 107.592 83.058  1.00 36.32  ? 271  SER   C O     1 
ATOM   964  C CB    . SER   A 1 271  ? 127.475 109.779 81.400  1.00 45.09  ? 271  SER   C CB    1 
ATOM   965  O OG    . SER   A 1 271  ? 126.579 108.767 81.774  1.00 41.81  ? 271  SER   C OG    1 
ATOM   966  N N     . LEU   A 1 272  ? 128.914 109.544 83.950  1.00 35.54  ? 272  LEU   C N     1 
ATOM   967  C CA    . LEU   A 1 272  ? 129.108 109.027 85.292  1.00 31.50  ? 272  LEU   C CA    1 
ATOM   968  C C     . LEU   A 1 272  ? 127.896 108.179 85.660  1.00 30.55  ? 272  LEU   C C     1 
ATOM   969  O O     . LEU   A 1 272  ? 127.112 108.522 86.545  1.00 28.81  ? 272  LEU   C O     1 
ATOM   970  C CB    . LEU   A 1 272  ? 129.271 110.178 86.288  1.00 31.13  ? 272  LEU   C CB    1 
ATOM   971  C CG    . LEU   A 1 272  ? 129.678 109.793 87.722  1.00 28.94  ? 272  LEU   C CG    1 
ATOM   972  C CD1   . LEU   A 1 272  ? 131.103 109.253 87.741  1.00 31.10  ? 272  LEU   C CD1   1 
ATOM   973  C CD2   . LEU   A 1 272  ? 129.553 110.996 88.610  1.00 29.03  ? 272  LEU   C CD2   1 
ATOM   974  N N     . GLY   A 1 273  ? 127.758 107.060 84.949  1.00 32.32  ? 273  GLY   C N     1 
ATOM   975  C CA    . GLY   A 1 273  ? 126.647 106.138 85.090  1.00 28.15  ? 273  GLY   C CA    1 
ATOM   976  C C     . GLY   A 1 273  ? 127.008 105.007 86.031  1.00 26.31  ? 273  GLY   C C     1 
ATOM   977  O O     . GLY   A 1 273  ? 126.216 104.096 86.259  1.00 26.24  ? 273  GLY   C O     1 
ATOM   978  N N     . ASP   A 1 274  ? 128.199 105.074 86.610  1.00 26.02  ? 274  ASP   C N     1 
ATOM   979  C CA    . ASP   A 1 274  ? 128.614 104.063 87.564  1.00 25.67  ? 274  ASP   C CA    1 
ATOM   980  C C     . ASP   A 1 274  ? 127.940 104.322 88.908  1.00 24.80  ? 274  ASP   C C     1 
ATOM   981  O O     . ASP   A 1 274  ? 127.949 103.472 89.800  1.00 26.22  ? 274  ASP   C O     1 
ATOM   982  C CB    . ASP   A 1 274  ? 130.142 103.998 87.654  1.00 26.26  ? 274  ASP   C CB    1 
ATOM   983  C CG    . ASP   A 1 274  ? 130.788 105.315 87.973  1.00 27.40  ? 274  ASP   C CG    1 
ATOM   984  O OD1   . ASP   A 1 274  ? 130.100 106.204 88.397  1.00 28.96  ? 274  ASP   C OD1   1 
ATOM   985  O OD2   . ASP   A 1 274  ? 131.967 105.439 87.734  1.00 26.27  ? 274  ASP   C OD2   1 
ATOM   986  N N     . LEU   A 1 275  ? 127.233 105.449 88.988  1.00 21.17  ? 275  LEU   C N     1 
ATOM   987  C CA    . LEU   A 1 275  ? 126.368 105.747 90.117  1.00 18.45  ? 275  LEU   C CA    1 
ATOM   988  C C     . LEU   A 1 275  ? 125.087 104.943 89.990  1.00 22.10  ? 275  LEU   C C     1 
ATOM   989  O O     . LEU   A 1 275  ? 124.314 104.844 90.937  1.00 25.58  ? 275  LEU   C O     1 
ATOM   990  C CB    . LEU   A 1 275  ? 126.025 107.238 90.174  1.00 19.49  ? 275  LEU   C CB    1 
ATOM   991  C CG    . LEU   A 1 275  ? 127.163 108.193 90.523  1.00 22.15  ? 275  LEU   C CG    1 
ATOM   992  C CD1   . LEU   A 1 275  ? 126.693 109.620 90.308  1.00 32.18  ? 275  LEU   C CD1   1 
ATOM   993  C CD2   . LEU   A 1 275  ? 127.566 107.995 91.975  1.00 22.95  ? 275  LEU   C CD2   1 
ATOM   994  N N     . ILE   A 1 276  ? 124.862 104.380 88.806  1.00 22.66  ? 276  ILE   C N     1 
ATOM   995  C CA    . ILE   A 1 276  ? 123.705 103.540 88.550  1.00 24.22  ? 276  ILE   C CA    1 
ATOM   996  C C     . ILE   A 1 276  ? 124.117 102.075 88.607  1.00 24.37  ? 276  ILE   C C     1 
ATOM   997  O O     . ILE   A 1 276  ? 123.442 101.254 89.220  1.00 26.79  ? 276  ILE   C O     1 
ATOM   998  C CB    . ILE   A 1 276  ? 123.078 103.861 87.184  1.00 27.17  ? 276  ILE   C CB    1 
ATOM   999  C CG1   . ILE   A 1 276  ? 122.598 105.318 87.184  1.00 31.18  ? 276  ILE   C CG1   1 
ATOM   1000 C CG2   . ILE   A 1 276  ? 121.915 102.900 86.906  1.00 27.99  ? 276  ILE   C CG2   1 
ATOM   1001 C CD1   . ILE   A 1 276  ? 122.241 105.855 85.819  1.00 36.34  ? 276  ILE   C CD1   1 
ATOM   1002 N N     . MET   A 1 277  ? 125.237 101.748 87.966  1.00 23.57  ? 277  MET   C N     1 
ATOM   1003 C CA    . MET   A 1 277  ? 125.714 100.368 87.909  1.00 21.75  ? 277  MET   C CA    1 
ATOM   1004 C C     . MET   A 1 277  ? 126.033 99.819  89.297  1.00 22.36  ? 277  MET   C C     1 
ATOM   1005 O O     . MET   A 1 277  ? 125.846 98.632  89.559  1.00 23.81  ? 277  MET   C O     1 
ATOM   1006 C CB    . MET   A 1 277  ? 126.951 100.273 87.020  1.00 22.61  ? 277  MET   C CB    1 
ATOM   1007 C CG    . MET   A 1 277  ? 126.680 100.501 85.542  1.00 34.67  ? 277  MET   C CG    1 
ATOM   1008 S SD    . MET   A 1 277  ? 128.120 100.169 84.498  1.00 0.00   ? 277  MET   C SD    1 
ATOM   1009 C CE    . MET   A 1 277  ? 129.118 101.638 84.772  1.00 0.00   ? 277  MET   C CE    1 
ATOM   1010 N N     . SER   A 1 278  ? 126.504 100.688 90.190  1.00 22.89  ? 278  SER   C N     1 
ATOM   1011 C CA    . SER   A 1 278  ? 126.849 100.294 91.552  1.00 22.97  ? 278  SER   C CA    1 
ATOM   1012 C C     . SER   A 1 278  ? 125.645 100.296 92.500  1.00 27.50  ? 278  SER   C C     1 
ATOM   1013 O O     . SER   A 1 278  ? 125.789 99.988  93.684  1.00 28.93  ? 278  SER   C O     1 
ATOM   1014 C CB    . SER   A 1 278  ? 127.929 101.204 92.103  1.00 18.25  ? 278  SER   C CB    1 
ATOM   1015 O OG    . SER   A 1 278  ? 127.471 102.520 92.210  1.00 20.12  ? 278  SER   C OG    1 
ATOM   1016 N N     . CYS   A 1 279  ? 124.467 100.663 91.993  1.00 26.32  ? 279  CYS   C N     1 
ATOM   1017 C CA    . CYS   A 1 279  ? 123.248 100.714 92.799  1.00 24.34  ? 279  CYS   C CA    1 
ATOM   1018 C C     . CYS   A 1 279  ? 122.500 99.398  92.827  1.00 27.89  ? 279  CYS   C C     1 
ATOM   1019 O O     . CYS   A 1 279  ? 122.811 98.470  92.080  1.00 29.62  ? 279  CYS   C O     1 
ATOM   1020 C CB    . CYS   A 1 279  ? 122.283 101.797 92.317  1.00 23.05  ? 279  CYS   C CB    1 
ATOM   1021 S SG    . CYS   A 1 279  ? 122.698 103.455 92.852  1.00 22.99  ? 279  CYS   C SG    1 
ATOM   1022 N N     . CYS   A 1 280  ? 121.502 99.336  93.698  1.00 28.21  ? 280  CYS   C N     1 
ATOM   1023 C CA    . CYS   A 1 280  ? 120.633 98.178  93.808  1.00 30.86  ? 280  CYS   C CA    1 
ATOM   1024 C C     . CYS   A 1 280  ? 120.047 97.884  92.420  1.00 35.89  ? 280  CYS   C C     1 
ATOM   1025 O O     . CYS   A 1 280  ? 120.174 98.720  91.531  1.00 36.48  ? 280  CYS   C O     1 
ATOM   1026 C CB    . CYS   A 1 280  ? 119.531 98.490  94.825  1.00 28.45  ? 280  CYS   C CB    1 
ATOM   1027 S SG    . CYS   A 1 280  ? 118.241 99.561  94.186  1.00 42.10  ? 280  CYS   C SG    1 
ATOM   1028 N N     . PRO   A 1 281  ? 119.379 96.736  92.213  1.00 41.72  ? 281  PRO   C N     1 
ATOM   1029 C CA    . PRO   A 1 281  ? 118.859 96.251  90.938  1.00 46.25  ? 281  PRO   C CA    1 
ATOM   1030 C C     . PRO   A 1 281  ? 117.924 97.226  90.222  1.00 48.66  ? 281  PRO   C C     1 
ATOM   1031 O O     . PRO   A 1 281  ? 117.715 97.107  89.016  1.00 49.94  ? 281  PRO   C O     1 
ATOM   1032 C CB    . PRO   A 1 281  ? 118.110 94.978  91.360  1.00 49.05  ? 281  PRO   C CB    1 
ATOM   1033 C CG    . PRO   A 1 281  ? 118.796 94.538  92.624  1.00 47.92  ? 281  PRO   C CG    1 
ATOM   1034 C CD    . PRO   A 1 281  ? 119.129 95.817  93.334  1.00 42.65  ? 281  PRO   C CD    1 
ATOM   1035 N N     . ASP   A 1 282  ? 117.341 98.169  90.951  1.00 45.71  ? 282  ASP   C N     1 
ATOM   1036 C CA    . ASP   A 1 282  ? 116.431 99.126  90.335  1.00 49.27  ? 282  ASP   C CA    1 
ATOM   1037 C C     . ASP   A 1 282  ? 117.186 99.978  89.312  1.00 49.99  ? 282  ASP   C C     1 
ATOM   1038 O O     . ASP   A 1 282  ? 118.070 100.742 89.693  1.00 41.47  ? 282  ASP   C O     1 
ATOM   1039 C CB    . ASP   A 1 282  ? 115.812 100.039 91.395  1.00 50.24  ? 282  ASP   C CB    1 
ATOM   1040 C CG    . ASP   A 1 282  ? 114.713 100.946 90.847  1.00 51.87  ? 282  ASP   C CG    1 
ATOM   1041 O OD1   . ASP   A 1 282  ? 114.730 101.247 89.670  1.00 55.18  ? 282  ASP   C OD1   1 
ATOM   1042 O OD2   . ASP   A 1 282  ? 113.858 101.324 91.618  1.00 55.19  ? 282  ASP   C OD2   1 
ATOM   1043 N N     . PRO   A 1 283  ? 116.853 99.876  88.017  1.00 52.06  ? 283  PRO   C N     1 
ATOM   1044 C CA    . PRO   A 1 283  ? 117.541 100.495 86.897  1.00 50.52  ? 283  PRO   C CA    1 
ATOM   1045 C C     . PRO   A 1 283  ? 117.381 102.012 86.843  1.00 49.81  ? 283  PRO   C C     1 
ATOM   1046 O O     . PRO   A 1 283  ? 118.059 102.680 86.061  1.00 48.72  ? 283  PRO   C O     1 
ATOM   1047 C CB    . PRO   A 1 283  ? 116.878 99.819  85.692  1.00 51.37  ? 283  PRO   C CB    1 
ATOM   1048 C CG    . PRO   A 1 283  ? 115.500 99.433  86.173  1.00 52.19  ? 283  PRO   C CG    1 
ATOM   1049 C CD    . PRO   A 1 283  ? 115.668 99.088  87.633  1.00 51.24  ? 283  PRO   C CD    1 
ATOM   1050 N N     . ASN   A 1 284  ? 116.475 102.563 87.652  1.00 50.27  ? 284  ASN   C N     1 
ATOM   1051 C CA    . ASN   A 1 284  ? 116.228 104.003 87.617  1.00 48.99  ? 284  ASN   C CA    1 
ATOM   1052 C C     . ASN   A 1 284  ? 116.278 104.656 89.001  1.00 47.29  ? 284  ASN   C C     1 
ATOM   1053 O O     . ASN   A 1 284  ? 115.256 105.140 89.489  1.00 45.93  ? 284  ASN   C O     1 
ATOM   1054 C CB    . ASN   A 1 284  ? 114.887 104.290 86.973  1.00 52.51  ? 284  ASN   C CB    1 
ATOM   1055 C CG    . ASN   A 1 284  ? 114.810 103.809 85.555  1.00 55.35  ? 284  ASN   C CG    1 
ATOM   1056 O OD1   . ASN   A 1 284  ? 115.443 104.371 84.654  1.00 57.93  ? 284  ASN   C OD1   1 
ATOM   1057 N ND2   . ASN   A 1 284  ? 114.034 102.782 85.339  1.00 54.24  ? 284  ASN   C ND2   1 
ATOM   1058 N N     . PRO   A 1 285  ? 117.453 104.701 89.641  1.00 40.16  ? 285  PRO   C N     1 
ATOM   1059 C CA    . PRO   A 1 285  ? 117.693 105.279 90.946  1.00 35.26  ? 285  PRO   C CA    1 
ATOM   1060 C C     . PRO   A 1 285  ? 117.569 106.798 90.874  1.00 34.55  ? 285  PRO   C C     1 
ATOM   1061 O O     . PRO   A 1 285  ? 117.744 107.382 89.805  1.00 39.57  ? 285  PRO   C O     1 
ATOM   1062 C CB    . PRO   A 1 285  ? 119.126 104.827 91.245  1.00 34.46  ? 285  PRO   C CB    1 
ATOM   1063 C CG    . PRO   A 1 285  ? 119.750 104.626 89.892  1.00 33.01  ? 285  PRO   C CG    1 
ATOM   1064 C CD    . PRO   A 1 285  ? 118.644 104.127 89.012  1.00 38.48  ? 285  PRO   C CD    1 
ATOM   1065 N N     . PRO   A 1 286  ? 117.319 107.459 92.005  1.00 33.11  ? 286  PRO   C N     1 
ATOM   1066 C CA    . PRO   A 1 286  ? 117.164 108.891 92.158  1.00 37.28  ? 286  PRO   C CA    1 
ATOM   1067 C C     . PRO   A 1 286  ? 118.501 109.618 92.103  1.00 35.27  ? 286  PRO   C C     1 
ATOM   1068 O O     . PRO   A 1 286  ? 118.927 110.240 93.074  1.00 36.86  ? 286  PRO   C O     1 
ATOM   1069 C CB    . PRO   A 1 286  ? 116.514 108.983 93.538  1.00 36.38  ? 286  PRO   C CB    1 
ATOM   1070 C CG    . PRO   A 1 286  ? 117.064 107.796 94.285  1.00 33.17  ? 286  PRO   C CG    1 
ATOM   1071 C CD    . PRO   A 1 286  ? 117.158 106.699 93.247  1.00 33.03  ? 286  PRO   C CD    1 
ATOM   1072 N N     . ILE   A 1 287  ? 119.146 109.544 90.946  1.00 35.76  ? 287  ILE   C N     1 
ATOM   1073 C CA    . ILE   A 1 287  ? 120.465 110.129 90.743  1.00 36.55  ? 287  ILE   C CA    1 
ATOM   1074 C C     . ILE   A 1 287  ? 120.430 111.642 90.887  1.00 41.49  ? 287  ILE   C C     1 
ATOM   1075 O O     . ILE   A 1 287  ? 121.423 112.253 91.268  1.00 44.68  ? 287  ILE   C O     1 
ATOM   1076 C CB    . ILE   A 1 287  ? 121.047 109.746 89.364  1.00 36.32  ? 287  ILE   C CB    1 
ATOM   1077 C CG1   . ILE   A 1 287  ? 121.223 108.213 89.250  1.00 35.54  ? 287  ILE   C CG1   1 
ATOM   1078 C CG2   . ILE   A 1 287  ? 122.383 110.444 89.130  1.00 35.79  ? 287  ILE   C CG2   1 
ATOM   1079 C CD1   . ILE   A 1 287  ? 122.114 107.568 90.309  1.00 31.06  ? 287  ILE   C CD1   1 
ATOM   1080 N N     . HIS   A 1 288  ? 119.295 112.251 90.561  1.00 43.47  ? 288  HIS   C N     1 
ATOM   1081 C CA    . HIS   A 1 288  ? 119.163 113.703 90.607  1.00 48.91  ? 288  HIS   C CA    1 
ATOM   1082 C C     . HIS   A 1 288  ? 118.706 114.220 91.972  1.00 49.24  ? 288  HIS   C C     1 
ATOM   1083 O O     . HIS   A 1 288  ? 118.420 115.409 92.120  1.00 51.50  ? 288  HIS   C O     1 
ATOM   1084 C CB    . HIS   A 1 288  ? 118.159 114.180 89.554  1.00 52.65  ? 288  HIS   C CB    1 
ATOM   1085 C CG    . HIS   A 1 288  ? 118.593 113.979 88.137  1.00 53.45  ? 288  HIS   C CG    1 
ATOM   1086 N ND1   . HIS   A 1 288  ? 119.381 114.890 87.462  1.00 56.43  ? 288  HIS   C ND1   1 
ATOM   1087 C CD2   . HIS   A 1 288  ? 118.349 112.975 87.266  1.00 57.16  ? 288  HIS   C CD2   1 
ATOM   1088 C CE1   . HIS   A 1 288  ? 119.596 114.454 86.234  1.00 56.46  ? 288  HIS   C CE1   1 
ATOM   1089 N NE2   . HIS   A 1 288  ? 118.983 113.295 86.091  1.00 61.77  ? 288  HIS   C NE2   1 
ATOM   1090 N N     . LYS   A 1 289  ? 118.616 113.339 92.966  1.00 43.12  ? 289  LYS   C N     1 
ATOM   1091 C CA    . LYS   A 1 289  ? 118.181 113.763 94.293  1.00 40.31  ? 289  LYS   C CA    1 
ATOM   1092 C C     . LYS   A 1 289  ? 119.355 113.799 95.262  1.00 38.68  ? 289  LYS   C C     1 
ATOM   1093 O O     . LYS   A 1 289  ? 120.407 114.358 94.956  1.00 40.68  ? 289  LYS   C O     1 
ATOM   1094 C CB    . LYS   A 1 289  ? 117.089 112.830 94.818  1.00 41.33  ? 289  LYS   C CB    1 
ATOM   1095 C CG    . LYS   A 1 289  ? 115.846 112.743 93.936  1.00 47.63  ? 289  LYS   C CG    1 
ATOM   1096 C CD    . LYS   A 1 289  ? 115.084 114.061 93.893  1.00 53.55  ? 289  LYS   C CD    1 
ATOM   1097 C CE    . LYS   A 1 289  ? 113.783 113.914 93.123  1.00 58.27  ? 289  LYS   C CE    1 
ATOM   1098 N NZ    . LYS   A 1 289  ? 113.042 115.201 93.033  1.00 68.45  ? 289  LYS   C NZ    1 
ATOM   1099 N N     . ILE   A 1 290  ? 119.189 113.176 96.426  1.00 38.15  ? 290  ILE   C N     1 
ATOM   1100 C CA    . ILE   A 1 290  ? 120.223 113.177 97.458  1.00 42.17  ? 290  ILE   C CA    1 
ATOM   1101 C C     . ILE   A 1 290  ? 121.540 112.574 96.973  1.00 42.41  ? 290  ILE   C C     1 
ATOM   1102 O O     . ILE   A 1 290  ? 122.612 112.940 97.453  1.00 37.77  ? 290  ILE   C O     1 
ATOM   1103 C CB    . ILE   A 1 290  ? 119.735 112.437 98.721  1.00 44.96  ? 290  ILE   C CB    1 
ATOM   1104 C CG1   . ILE   A 1 290  ? 120.721 112.697 99.885  1.00 39.45  ? 290  ILE   C CG1   1 
ATOM   1105 C CG2   . ILE   A 1 290  ? 119.567 110.944 98.438  1.00 34.20  ? 290  ILE   C CG2   1 
ATOM   1106 C CD1   . ILE   A 1 290  ? 120.196 112.294 101.246 1.00 36.66  ? 290  ILE   C CD1   1 
ATOM   1107 N N     . VAL   A 1 291  ? 121.460 111.663 96.013  1.00 36.84  ? 291  VAL   C N     1 
ATOM   1108 C CA    . VAL   A 1 291  ? 122.634 111.010 95.456  1.00 28.30  ? 291  VAL   C CA    1 
ATOM   1109 C C     . VAL   A 1 291  ? 123.564 112.012 94.768  1.00 30.35  ? 291  VAL   C C     1 
ATOM   1110 O O     . VAL   A 1 291  ? 124.739 111.723 94.545  1.00 30.49  ? 291  VAL   C O     1 
ATOM   1111 C CB    . VAL   A 1 291  ? 122.191 109.906 94.469  1.00 28.28  ? 291  VAL   C CB    1 
ATOM   1112 C CG1   . VAL   A 1 291  ? 123.386 109.334 93.712  1.00 32.40  ? 291  VAL   C CG1   1 
ATOM   1113 C CG2   . VAL   A 1 291  ? 121.492 108.803 95.246  1.00 21.44  ? 291  VAL   C CG2   1 
ATOM   1114 N N     . ARG   A 1 292  ? 123.027 113.177 94.408  1.00 34.09  ? 292  ARG   C N     1 
ATOM   1115 C CA    . ARG   A 1 292  ? 123.782 114.205 93.707  1.00 32.61  ? 292  ARG   C CA    1 
ATOM   1116 C C     . ARG   A 1 292  ? 124.392 115.243 94.648  1.00 36.10  ? 292  ARG   C C     1 
ATOM   1117 O O     . ARG   A 1 292  ? 125.004 116.206 94.190  1.00 35.83  ? 292  ARG   C O     1 
ATOM   1118 C CB    . ARG   A 1 292  ? 122.872 114.906 92.708  1.00 46.63  ? 292  ARG   C CB    1 
ATOM   1119 C CG    . ARG   A 1 292  ? 123.523 115.938 91.791  1.00 58.19  ? 292  ARG   C CG    1 
ATOM   1120 C CD    . ARG   A 1 292  ? 122.578 116.387 90.737  1.00 58.09  ? 292  ARG   C CD    1 
ATOM   1121 N NE    . ARG   A 1 292  ? 121.441 117.108 91.297  1.00 63.66  ? 292  ARG   C NE    1 
ATOM   1122 C CZ    . ARG   A 1 292  ? 120.348 117.487 90.600  1.00 65.21  ? 292  ARG   C CZ    1 
ATOM   1123 N NH1   . ARG   A 1 292  ? 120.249 117.209 89.318  1.00 65.14  ? 292  ARG   C NH1   1 
ATOM   1124 N NH2   . ARG   A 1 292  ? 119.374 118.139 91.212  1.00 70.88  ? 292  ARG   C NH2   1 
ATOM   1125 N N     . LYS   A 1 293  ? 124.229 115.063 95.958  1.00 37.06  ? 293  LYS   C N     1 
ATOM   1126 C CA    . LYS   A 1 293  ? 124.753 116.041 96.911  1.00 32.63  ? 293  LYS   C CA    1 
ATOM   1127 C C     . LYS   A 1 293  ? 126.196 115.727 97.333  1.00 26.10  ? 293  LYS   C C     1 
ATOM   1128 O O     . LYS   A 1 293  ? 126.434 114.764 98.065  1.00 24.64  ? 293  LYS   C O     1 
ATOM   1129 C CB    . LYS   A 1 293  ? 123.858 116.100 98.151  1.00 32.04  ? 293  LYS   C CB    1 
ATOM   1130 C CG    . LYS   A 1 293  ? 124.261 117.152 99.178  1.00 28.23  ? 293  LYS   C CG    1 
ATOM   1131 C CD    . LYS   A 1 293  ? 123.263 117.213 100.333 1.00 32.34  ? 293  LYS   C CD    1 
ATOM   1132 C CE    . LYS   A 1 293  ? 123.685 118.246 101.373 1.00 39.28  ? 293  LYS   C CE    1 
ATOM   1133 N NZ    . LYS   A 1 293  ? 122.704 118.346 102.493 1.00 32.24  ? 293  LYS   C NZ    1 
ATOM   1134 N N     . PRO   A 1 294  ? 127.171 116.550 96.936  1.00 22.90  ? 294  PRO   C N     1 
ATOM   1135 C CA    . PRO   A 1 294  ? 128.583 116.337 97.151  1.00 20.57  ? 294  PRO   C CA    1 
ATOM   1136 C C     . PRO   A 1 294  ? 128.893 116.487 98.624  1.00 21.84  ? 294  PRO   C C     1 
ATOM   1137 O O     . PRO   A 1 294  ? 128.172 117.180 99.338  1.00 22.93  ? 294  PRO   C O     1 
ATOM   1138 C CB    . PRO   A 1 294  ? 129.225 117.434 96.305  1.00 29.03  ? 294  PRO   C CB    1 
ATOM   1139 C CG    . PRO   A 1 294  ? 128.186 118.531 96.246  1.00 34.18  ? 294  PRO   C CG    1 
ATOM   1140 C CD    . PRO   A 1 294  ? 126.845 117.819 96.273  1.00 31.15  ? 294  PRO   C CD    1 
ATOM   1141 N N     . SER   A 1 295  ? 129.963 115.833 99.062  1.00 20.61  ? 295  SER   C N     1 
ATOM   1142 C CA    . SER   A 1 295  ? 130.439 115.844 100.446 1.00 18.92  ? 295  SER   C CA    1 
ATOM   1143 C C     . SER   A 1 295  ? 129.701 114.818 101.301 1.00 18.02  ? 295  SER   C C     1 
ATOM   1144 O O     . SER   A 1 295  ? 130.121 114.523 102.420 1.00 18.65  ? 295  SER   C O     1 
ATOM   1145 C CB    . SER   A 1 295  ? 130.308 117.218 101.079 1.00 23.81  ? 295  SER   C CB    1 
ATOM   1146 O OG    . SER   A 1 295  ? 129.038 117.406 101.640 1.00 23.22  ? 295  SER   C OG    1 
ATOM   1147 N N     . ARG   A 1 296  ? 128.619 114.247 100.769 1.00 16.93  ? 296  ARG   C N     1 
ATOM   1148 C CA    . ARG   A 1 296  ? 127.881 113.217 101.489 1.00 13.68  ? 296  ARG   C CA    1 
ATOM   1149 C C     . ARG   A 1 296  ? 128.135 111.838 100.900 1.00 13.27  ? 296  ARG   C C     1 
ATOM   1150 O O     . ARG   A 1 296  ? 127.535 110.848 101.331 1.00 16.74  ? 296  ARG   C O     1 
ATOM   1151 C CB    . ARG   A 1 296  ? 126.391 113.501 101.463 1.00 17.60  ? 296  ARG   C CB    1 
ATOM   1152 C CG    . ARG   A 1 296  ? 125.963 114.830 102.072 1.00 23.98  ? 296  ARG   C CG    1 
ATOM   1153 C CD    . ARG   A 1 296  ? 126.189 114.877 103.545 1.00 17.71  ? 296  ARG   C CD    1 
ATOM   1154 N NE    . ARG   A 1 296  ? 125.449 113.833 104.245 1.00 15.82  ? 296  ARG   C NE    1 
ATOM   1155 C CZ    . ARG   A 1 296  ? 125.601 113.527 105.549 1.00 17.00  ? 296  ARG   C CZ    1 
ATOM   1156 N NH1   . ARG   A 1 296  ? 126.453 114.202 106.292 1.00 17.50  ? 296  ARG   C NH1   1 
ATOM   1157 N NH2   . ARG   A 1 296  ? 124.899 112.545 106.086 1.00 18.08  ? 296  ARG   C NH2   1 
ATOM   1158 N N     . ILE   A 1 297  ? 129.010 111.770 99.903  1.00 12.31  ? 297  ILE   C N     1 
ATOM   1159 C CA    . ILE   A 1 297  ? 129.304 110.493 99.272  1.00 7.43   ? 297  ILE   C CA    1 
ATOM   1160 C C     . ILE   A 1 297  ? 130.801 110.222 99.228  1.00 7.36   ? 297  ILE   C C     1 
ATOM   1161 O O     . ILE   A 1 297  ? 131.608 111.148 99.104  1.00 12.31  ? 297  ILE   C O     1 
ATOM   1162 C CB    . ILE   A 1 297  ? 128.720 110.433 97.845  1.00 7.01   ? 297  ILE   C CB    1 
ATOM   1163 C CG1   . ILE   A 1 297  ? 129.396 111.464 96.928  1.00 8.67   ? 297  ILE   C CG1   1 
ATOM   1164 C CG2   . ILE   A 1 297  ? 127.215 110.707 97.912  1.00 11.96  ? 297  ILE   C CG2   1 
ATOM   1165 C CD1   . ILE   A 1 297  ? 129.053 111.295 95.463  1.00 8.82   ? 297  ILE   C CD1   1 
ATOM   1166 N N     . LEU   A 1 298  ? 131.152 108.944 99.295  1.00 7.28   ? 298  LEU   C N     1 
ATOM   1167 C CA    . LEU   A 1 298  ? 132.533 108.491 99.173  1.00 7.40   ? 298  LEU   C CA    1 
ATOM   1168 C C     . LEU   A 1 298  ? 132.661 107.418 98.110  1.00 0.11   ? 298  LEU   C C     1 
ATOM   1169 O O     . LEU   A 1 298  ? 131.954 106.410 98.138  1.00 8.03   ? 298  LEU   C O     1 
ATOM   1170 C CB    . LEU   A 1 298  ? 133.040 107.962 100.531 1.00 6.94   ? 298  LEU   C CB    1 
ATOM   1171 C CG    . LEU   A 1 298  ? 134.355 107.114 100.534 1.00 0.94   ? 298  LEU   C CG    1 
ATOM   1172 C CD1   . LEU   A 1 298  ? 135.509 107.958 100.105 1.00 6.06   ? 298  LEU   C CD1   1 
ATOM   1173 C CD2   . LEU   A 1 298  ? 134.614 106.573 101.932 1.00 11.04  ? 298  LEU   C CD2   1 
ATOM   1174 N N     . PHE   A 1 299  ? 133.578 107.629 97.182  1.00 0.35   ? 299  PHE   C N     1 
ATOM   1175 C CA    . PHE   A 1 299  ? 133.846 106.639 96.155  1.00 0.01   ? 299  PHE   C CA    1 
ATOM   1176 C C     . PHE   A 1 299  ? 134.997 105.757 96.599  1.00 0.03   ? 299  PHE   C C     1 
ATOM   1177 O O     . PHE   A 1 299  ? 135.989 106.250 97.136  1.00 0.00   ? 299  PHE   C O     1 
ATOM   1178 C CB    . PHE   A 1 299  ? 134.218 107.305 94.832  1.00 0.28   ? 299  PHE   C CB    1 
ATOM   1179 C CG    . PHE   A 1 299  ? 133.114 108.046 94.151  1.00 0.15   ? 299  PHE   C CG    1 
ATOM   1180 C CD1   . PHE   A 1 299  ? 133.022 109.423 94.255  1.00 1.85   ? 299  PHE   C CD1   1 
ATOM   1181 C CD2   . PHE   A 1 299  ? 132.176 107.378 93.393  1.00 1.89   ? 299  PHE   C CD2   1 
ATOM   1182 C CE1   . PHE   A 1 299  ? 132.019 110.110 93.612  1.00 10.19  ? 299  PHE   C CE1   1 
ATOM   1183 C CE2   . PHE   A 1 299  ? 131.172 108.063 92.752  1.00 12.97  ? 299  PHE   C CE2   1 
ATOM   1184 C CZ    . PHE   A 1 299  ? 131.094 109.431 92.862  1.00 11.66  ? 299  PHE   C CZ    1 
ATOM   1185 N N     . LEU   A 1 300  ? 134.890 104.465 96.347  1.00 0.03   ? 300  LEU   C N     1 
ATOM   1186 C CA    . LEU   A 1 300  ? 135.991 103.559 96.636  1.00 0.02   ? 300  LEU   C CA    1 
ATOM   1187 C C     . LEU   A 1 300  ? 136.569 103.040 95.334  1.00 12.05  ? 300  LEU   C C     1 
ATOM   1188 O O     . LEU   A 1 300  ? 135.949 102.223 94.655  1.00 14.64  ? 300  LEU   C O     1 
ATOM   1189 C CB    . LEU   A 1 300  ? 135.526 102.378 97.499  1.00 0.29   ? 300  LEU   C CB    1 
ATOM   1190 C CG    . LEU   A 1 300  ? 135.325 102.653 98.991  1.00 0.25   ? 300  LEU   C CG    1 
ATOM   1191 C CD1   . LEU   A 1 300  ? 133.946 103.268 99.232  1.00 0.03   ? 300  LEU   C CD1   1 
ATOM   1192 C CD2   . LEU   A 1 300  ? 135.471 101.351 99.753  1.00 0.51   ? 300  LEU   C CD2   1 
ATOM   1193 N N     . MET   A 1 301  ? 137.737 103.541 94.967  1.00 14.44  ? 301  MET   C N     1 
ATOM   1194 C CA    . MET   A 1 301  ? 138.361 103.178 93.704  1.00 12.21  ? 301  MET   C CA    1 
ATOM   1195 C C     . MET   A 1 301  ? 139.366 102.074 93.943  1.00 11.21  ? 301  MET   C C     1 
ATOM   1196 O O     . MET   A 1 301  ? 140.529 102.324 94.266  1.00 14.28  ? 301  MET   C O     1 
ATOM   1197 C CB    . MET   A 1 301  ? 138.997 104.402 93.063  1.00 13.38  ? 301  MET   C CB    1 
ATOM   1198 C CG    . MET   A 1 301  ? 139.567 104.167 91.688  1.00 15.07  ? 301  MET   C CG    1 
ATOM   1199 S SD    . MET   A 1 301  ? 140.221 105.666 90.945  1.00 30.91  ? 301  MET   C SD    1 
ATOM   1200 C CE    . MET   A 1 301  ? 138.722 106.589 90.570  1.00 24.06  ? 301  MET   C CE    1 
ATOM   1201 N N     . ASP   A 1 302  ? 138.879 100.850 93.852  1.00 12.10  ? 302  ASP   C N     1 
ATOM   1202 C CA    . ASP   A 1 302  ? 139.629 99.682  94.262  1.00 12.22  ? 302  ASP   C CA    1 
ATOM   1203 C C     . ASP   A 1 302  ? 140.439 99.065  93.124  1.00 16.23  ? 302  ASP   C C     1 
ATOM   1204 O O     . ASP   A 1 302  ? 139.872 98.614  92.124  1.00 20.03  ? 302  ASP   C O     1 
ATOM   1205 C CB    . ASP   A 1 302  ? 138.680 98.642  94.846  1.00 12.61  ? 302  ASP   C CB    1 
ATOM   1206 C CG    . ASP   A 1 302  ? 139.389 97.478  95.481  1.00 15.44  ? 302  ASP   C CG    1 
ATOM   1207 O OD1   . ASP   A 1 302  ? 140.600 97.511  95.575  1.00 16.64  ? 302  ASP   C OD1   1 
ATOM   1208 O OD2   . ASP   A 1 302  ? 138.713 96.554  95.879  1.00 18.48  ? 302  ASP   C OD2   1 
ATOM   1209 N N     . GLY   A 1 303  ? 141.765 99.071  93.265  1.00 15.35  ? 303  GLY   C N     1 
ATOM   1210 C CA    . GLY   A 1 303  ? 142.655 98.479  92.269  1.00 17.72  ? 303  GLY   C CA    1 
ATOM   1211 C C     . GLY   A 1 303  ? 143.058 99.431  91.151  1.00 17.44  ? 303  GLY   C C     1 
ATOM   1212 O O     . GLY   A 1 303  ? 142.975 99.083  89.976  1.00 21.03  ? 303  GLY   C O     1 
ATOM   1213 N N     . PHE   A 1 304  ? 143.523 100.622 91.497  1.00 14.02  ? 304  PHE   C N     1 
ATOM   1214 C CA    . PHE   A 1 304  ? 143.950 101.569 90.470  1.00 15.21  ? 304  PHE   C CA    1 
ATOM   1215 C C     . PHE   A 1 304  ? 144.956 100.924 89.520  1.00 18.07  ? 304  PHE   C C     1 
ATOM   1216 O O     . PHE   A 1 304  ? 144.902 101.117 88.306  1.00 21.06  ? 304  PHE   C O     1 
ATOM   1217 C CB    . PHE   A 1 304  ? 144.569 102.821 91.092  1.00 14.62  ? 304  PHE   C CB    1 
ATOM   1218 C CG    . PHE   A 1 304  ? 145.025 103.826 90.069  1.00 16.88  ? 304  PHE   C CG    1 
ATOM   1219 C CD1   . PHE   A 1 304  ? 144.111 104.668 89.449  1.00 20.16  ? 304  PHE   C CD1   1 
ATOM   1220 C CD2   . PHE   A 1 304  ? 146.361 103.932 89.722  1.00 17.27  ? 304  PHE   C CD2   1 
ATOM   1221 C CE1   . PHE   A 1 304  ? 144.524 105.590 88.507  1.00 23.27  ? 304  PHE   C CE1   1 
ATOM   1222 C CE2   . PHE   A 1 304  ? 146.776 104.852 88.781  1.00 20.87  ? 304  PHE   C CE2   1 
ATOM   1223 C CZ    . PHE   A 1 304  ? 145.856 105.683 88.173  1.00 26.17  ? 304  PHE   C CZ    1 
ATOM   1224 N N     . ASP   A 1 305  ? 145.883 100.158 90.076  1.00 16.89  ? 305  ASP   C N     1 
ATOM   1225 C CA    . ASP   A 1 305  ? 146.939 99.523  89.302  1.00 17.65  ? 305  ASP   C CA    1 
ATOM   1226 C C     . ASP   A 1 305  ? 146.434 98.409  88.389  1.00 20.27  ? 305  ASP   C C     1 
ATOM   1227 O O     . ASP   A 1 305  ? 147.177 97.921  87.538  1.00 22.44  ? 305  ASP   C O     1 
ATOM   1228 C CB    . ASP   A 1 305  ? 148.000 98.962  90.241  1.00 14.70  ? 305  ASP   C CB    1 
ATOM   1229 C CG    . ASP   A 1 305  ? 147.426 97.986  91.234  1.00 19.80  ? 305  ASP   C CG    1 
ATOM   1230 O OD1   . ASP   A 1 305  ? 146.800 98.442  92.164  1.00 18.64  ? 305  ASP   C OD1   1 
ATOM   1231 O OD2   . ASP   A 1 305  ? 147.609 96.806  91.074  1.00 22.14  ? 305  ASP   C OD2   1 
ATOM   1232 N N     . GLU   A 1 306  ? 145.185 97.989  88.573  1.00 20.10  ? 306  GLU   C N     1 
ATOM   1233 C CA    . GLU   A 1 306  ? 144.632 96.905  87.777  1.00 20.37  ? 306  GLU   C CA    1 
ATOM   1234 C C     . GLU   A 1 306  ? 143.945 97.408  86.519  1.00 22.83  ? 306  GLU   C C     1 
ATOM   1235 O O     . GLU   A 1 306  ? 143.432 96.611  85.733  1.00 27.00  ? 306  GLU   C O     1 
ATOM   1236 C CB    . GLU   A 1 306  ? 143.651 96.067  88.594  1.00 20.57  ? 306  GLU   C CB    1 
ATOM   1237 C CG    . GLU   A 1 306  ? 144.291 95.315  89.740  1.00 25.91  ? 306  GLU   C CG    1 
ATOM   1238 C CD    . GLU   A 1 306  ? 143.338 94.386  90.427  1.00 32.30  ? 306  GLU   C CD    1 
ATOM   1239 O OE1   . GLU   A 1 306  ? 142.768 93.560  89.757  1.00 33.98  ? 306  GLU   C OE1   1 
ATOM   1240 O OE2   . GLU   A 1 306  ? 143.181 94.496  91.624  1.00 33.35  ? 306  GLU   C OE2   1 
ATOM   1241 N N     . LEU   A 1 307  ? 143.918 98.722  86.322  1.00 20.92  ? 307  LEU   C N     1 
ATOM   1242 C CA    . LEU   A 1 307  ? 143.302 99.253  85.118  1.00 20.35  ? 307  LEU   C CA    1 
ATOM   1243 C C     . LEU   A 1 307  ? 144.045 98.706  83.914  1.00 26.39  ? 307  LEU   C C     1 
ATOM   1244 O O     . LEU   A 1 307  ? 145.273 98.752  83.863  1.00 28.90  ? 307  LEU   C O     1 
ATOM   1245 C CB    . LEU   A 1 307  ? 143.352 100.785 85.112  1.00 18.56  ? 307  LEU   C CB    1 
ATOM   1246 C CG    . LEU   A 1 307  ? 142.473 101.507 86.148  1.00 19.62  ? 307  LEU   C CG    1 
ATOM   1247 C CD1   . LEU   A 1 307  ? 142.855 102.980 86.179  1.00 22.09  ? 307  LEU   C CD1   1 
ATOM   1248 C CD2   . LEU   A 1 307  ? 140.997 101.342 85.778  1.00 25.59  ? 307  LEU   C CD2   1 
ATOM   1249 N N     . GLN   A 1 308  ? 143.304 98.168  82.957  1.00 28.88  ? 308  GLN   C N     1 
ATOM   1250 C CA    . GLN   A 1 308  ? 143.916 97.556  81.788  1.00 30.91  ? 308  GLN   C CA    1 
ATOM   1251 C C     . GLN   A 1 308  ? 144.021 98.523  80.626  1.00 32.87  ? 308  GLN   C C     1 
ATOM   1252 O O     . GLN   A 1 308  ? 143.052 99.195  80.274  1.00 33.32  ? 308  GLN   C O     1 
ATOM   1253 C CB    . GLN   A 1 308  ? 143.131 96.310  81.387  1.00 32.69  ? 308  GLN   C CB    1 
ATOM   1254 C CG    . GLN   A 1 308  ? 143.153 95.239  82.445  1.00 31.49  ? 308  GLN   C CG    1 
ATOM   1255 C CD    . GLN   A 1 308  ? 144.558 94.740  82.698  1.00 36.98  ? 308  GLN   C CD    1 
ATOM   1256 O OE1   . GLN   A 1 308  ? 145.161 94.068  81.858  1.00 38.97  ? 308  GLN   C OE1   1 
ATOM   1257 N NE2   . GLN   A 1 308  ? 145.095 95.079  83.860  1.00 34.15  ? 308  GLN   C NE2   1 
ATOM   1258 N N     . GLY   A 1 309  ? 145.201 98.576  80.022  1.00 32.95  ? 309  GLY   C N     1 
ATOM   1259 C CA    . GLY   A 1 309  ? 145.452 99.463  78.896  1.00 33.87  ? 309  GLY   C CA    1 
ATOM   1260 C C     . GLY   A 1 309  ? 146.241 100.686 79.336  1.00 31.39  ? 309  GLY   C C     1 
ATOM   1261 O O     . GLY   A 1 309  ? 146.413 100.934 80.529  1.00 31.32  ? 309  GLY   C O     1 
ATOM   1262 N N     . ALA   A 1 310  ? 146.741 101.446 78.371  1.00 30.57  ? 310  ALA   C N     1 
ATOM   1263 C CA    . ALA   A 1 310  ? 147.531 102.625 78.686  1.00 30.79  ? 310  ALA   C CA    1 
ATOM   1264 C C     . ALA   A 1 310  ? 146.677 103.668 79.381  1.00 31.10  ? 310  ALA   C C     1 
ATOM   1265 O O     . ALA   A 1 310  ? 145.518 103.872 79.025  1.00 34.14  ? 310  ALA   C O     1 
ATOM   1266 C CB    . ALA   A 1 310  ? 148.141 103.209 77.425  1.00 33.29  ? 310  ALA   C CB    1 
ATOM   1267 N N     . PHE   A 1 311  ? 147.263 104.340 80.360  1.00 30.85  ? 311  PHE   C N     1 
ATOM   1268 C CA    . PHE   A 1 311  ? 146.571 105.393 81.083  1.00 32.63  ? 311  PHE   C CA    1 
ATOM   1269 C C     . PHE   A 1 311  ? 147.337 106.706 80.972  1.00 38.49  ? 311  PHE   C C     1 
ATOM   1270 O O     . PHE   A 1 311  ? 148.466 106.812 81.449  1.00 37.13  ? 311  PHE   C O     1 
ATOM   1271 C CB    . PHE   A 1 311  ? 146.404 105.001 82.550  1.00 31.31  ? 311  PHE   C CB    1 
ATOM   1272 C CG    . PHE   A 1 311  ? 145.569 105.948 83.328  1.00 30.21  ? 311  PHE   C CG    1 
ATOM   1273 C CD1   . PHE   A 1 311  ? 144.232 105.674 83.560  1.00 29.33  ? 311  PHE   C CD1   1 
ATOM   1274 C CD2   . PHE   A 1 311  ? 146.104 107.114 83.824  1.00 31.88  ? 311  PHE   C CD2   1 
ATOM   1275 C CE1   . PHE   A 1 311  ? 143.451 106.549 84.273  1.00 31.44  ? 311  PHE   C CE1   1 
ATOM   1276 C CE2   . PHE   A 1 311  ? 145.331 107.990 84.533  1.00 32.16  ? 311  PHE   C CE2   1 
ATOM   1277 C CZ    . PHE   A 1 311  ? 143.999 107.711 84.761  1.00 32.22  ? 311  PHE   C CZ    1 
ATOM   1278 N N     . ASP   A 1 312  ? 146.728 107.691 80.319  1.00 41.98  ? 312  ASP   C N     1 
ATOM   1279 C CA    . ASP   A 1 312  ? 147.353 108.996 80.106  1.00 44.20  ? 312  ASP   C CA    1 
ATOM   1280 C C     . ASP   A 1 312  ? 146.906 109.999 81.167  1.00 46.53  ? 312  ASP   C C     1 
ATOM   1281 O O     . ASP   A 1 312  ? 145.727 110.347 81.243  1.00 46.63  ? 312  ASP   C O     1 
ATOM   1282 C CB    . ASP   A 1 312  ? 147.031 109.530 78.710  1.00 47.29  ? 312  ASP   C CB    1 
ATOM   1283 C CG    . ASP   A 1 312  ? 147.817 110.788 78.370  1.00 53.74  ? 312  ASP   C CG    1 
ATOM   1284 O OD1   . ASP   A 1 312  ? 148.371 111.387 79.269  1.00 51.45  ? 312  ASP   C OD1   1 
ATOM   1285 O OD2   . ASP   A 1 312  ? 147.868 111.132 77.213  1.00 56.59  ? 312  ASP   C OD2   1 
ATOM   1286 N N     . GLU   A 1 313  ? 147.838 110.418 82.016  1.00 45.01  ? 313  GLU   C N     1 
ATOM   1287 C CA    . GLU   A 1 313  ? 147.533 111.297 83.139  1.00 45.76  ? 313  GLU   C CA    1 
ATOM   1288 C C     . GLU   A 1 313  ? 147.473 112.778 82.739  1.00 48.66  ? 313  GLU   C C     1 
ATOM   1289 O O     . GLU   A 1 313  ? 147.119 113.628 83.559  1.00 47.83  ? 313  GLU   C O     1 
ATOM   1290 C CB    . GLU   A 1 313  ? 148.552 111.084 84.273  1.00 41.47  ? 313  GLU   C CB    1 
ATOM   1291 C CG    . GLU   A 1 313  ? 149.929 111.697 84.050  1.00 44.15  ? 313  GLU   C CG    1 
ATOM   1292 C CD    . GLU   A 1 313  ? 150.846 110.846 83.213  1.00 46.10  ? 313  GLU   C CD    1 
ATOM   1293 O OE1   . GLU   A 1 313  ? 150.357 110.081 82.420  1.00 45.66  ? 313  GLU   C OE1   1 
ATOM   1294 O OE2   . GLU   A 1 313  ? 152.037 110.962 83.366  1.00 44.66  ? 313  GLU   C OE2   1 
ATOM   1295 N N     . HIS   A 1 314  ? 147.830 113.091 81.490  1.00 51.25  ? 314  HIS   C N     1 
ATOM   1296 C CA    . HIS   A 1 314  ? 147.855 114.482 81.031  1.00 53.62  ? 314  HIS   C CA    1 
ATOM   1297 C C     . HIS   A 1 314  ? 146.879 114.718 79.889  1.00 54.67  ? 314  HIS   C C     1 
ATOM   1298 O O     . HIS   A 1 314  ? 147.180 114.442 78.728  1.00 54.80  ? 314  HIS   C O     1 
ATOM   1299 C CB    . HIS   A 1 314  ? 149.255 114.883 80.559  1.00 53.34  ? 314  HIS   C CB    1 
ATOM   1300 C CG    . HIS   A 1 314  ? 150.292 114.852 81.625  1.00 51.29  ? 314  HIS   C CG    1 
ATOM   1301 N ND1   . HIS   A 1 314  ? 150.342 115.780 82.644  1.00 49.01  ? 314  HIS   C ND1   1 
ATOM   1302 C CD2   . HIS   A 1 314  ? 151.328 114.011 81.829  1.00 50.94  ? 314  HIS   C CD2   1 
ATOM   1303 C CE1   . HIS   A 1 314  ? 151.363 115.502 83.435  1.00 49.30  ? 314  HIS   C CE1   1 
ATOM   1304 N NE2   . HIS   A 1 314  ? 151.977 114.434 82.961  1.00 49.64  ? 314  HIS   C NE2   1 
ATOM   1305 N N     . ILE   A 1 315  ? 145.709 115.245 80.224  1.00 58.98  ? 315  ILE   C N     1 
ATOM   1306 C CA    . ILE   A 1 315  ? 144.655 115.437 79.240  1.00 61.08  ? 315  ILE   C CA    1 
ATOM   1307 C C     . ILE   A 1 315  ? 144.139 116.873 79.223  1.00 59.96  ? 315  ILE   C C     1 
ATOM   1308 O O     . ILE   A 1 315  ? 144.286 117.611 80.197  1.00 62.54  ? 315  ILE   C O     1 
ATOM   1309 C CB    . ILE   A 1 315  ? 143.482 114.482 79.512  1.00 58.90  ? 315  ILE   C CB    1 
ATOM   1310 C CG1   . ILE   A 1 315  ? 142.884 114.786 80.893  1.00 57.36  ? 315  ILE   C CG1   1 
ATOM   1311 C CG2   . ILE   A 1 315  ? 143.970 113.030 79.440  1.00 53.79  ? 315  ILE   C CG2   1 
ATOM   1312 C CD1   . ILE   A 1 315  ? 141.567 114.121 81.144  1.00 52.30  ? 315  ILE   C CD1   1 
ATOM   1313 N N     . GLY   A 1 316  ? 143.500 117.235 78.117  1.00 60.65  ? 316  GLY   C N     1 
ATOM   1314 C CA    . GLY   A 1 316  ? 142.848 118.529 77.945  1.00 60.72  ? 316  GLY   C CA    1 
ATOM   1315 C C     . GLY   A 1 316  ? 141.429 118.562 78.529  1.00 57.98  ? 316  GLY   C C     1 
ATOM   1316 O O     . GLY   A 1 316  ? 141.170 119.271 79.503  1.00 56.69  ? 316  GLY   C O     1 
ATOM   1317 N N     . PRO   A 1 317  ? 140.485 117.832 77.927  1.00 58.24  ? 317  PRO   C N     1 
ATOM   1318 C CA    . PRO   A 1 317  ? 139.077 117.788 78.267  1.00 56.69  ? 317  PRO   C CA    1 
ATOM   1319 C C     . PRO   A 1 317  ? 138.818 116.986 79.530  1.00 54.63  ? 317  PRO   C C     1 
ATOM   1320 O O     . PRO   A 1 317  ? 138.470 115.810 79.462  1.00 54.12  ? 317  PRO   C O     1 
ATOM   1321 C CB    . PRO   A 1 317  ? 138.464 117.124 77.032  1.00 57.78  ? 317  PRO   C CB    1 
ATOM   1322 C CG    . PRO   A 1 317  ? 139.557 116.227 76.506  1.00 56.85  ? 317  PRO   C CG    1 
ATOM   1323 C CD    . PRO   A 1 317  ? 140.852 116.959 76.794  1.00 57.64  ? 317  PRO   C CD    1 
ATOM   1324 N N     . LEU   A 1 318  ? 138.972 117.636 80.678  1.00 52.51  ? 318  LEU   C N     1 
ATOM   1325 C CA    . LEU   A 1 318  ? 138.788 116.988 81.977  1.00 52.00  ? 318  LEU   C CA    1 
ATOM   1326 C C     . LEU   A 1 318  ? 137.367 116.468 82.149  1.00 48.71  ? 318  LEU   C C     1 
ATOM   1327 O O     . LEU   A 1 318  ? 137.126 115.561 82.941  1.00 48.58  ? 318  LEU   C O     1 
ATOM   1328 C CB    . LEU   A 1 318  ? 139.110 117.971 83.112  1.00 45.92  ? 318  LEU   C CB    1 
ATOM   1329 C CG    . LEU   A 1 318  ? 140.569 117.987 83.627  1.00 49.31  ? 318  LEU   C CG    1 
ATOM   1330 C CD1   . LEU   A 1 318  ? 140.863 116.703 84.392  1.00 44.78  ? 318  LEU   C CD1   1 
ATOM   1331 C CD2   . LEU   A 1 318  ? 141.517 118.143 82.452  1.00 55.78  ? 318  LEU   C CD2   1 
ATOM   1332 N N     . CYS   A 1 319  ? 136.433 117.052 81.407  1.00 48.95  ? 319  CYS   C N     1 
ATOM   1333 C CA    . CYS   A 1 319  ? 135.038 116.624 81.397  1.00 49.43  ? 319  CYS   C CA    1 
ATOM   1334 C C     . CYS   A 1 319  ? 134.298 116.810 82.708  1.00 44.67  ? 319  CYS   C C     1 
ATOM   1335 O O     . CYS   A 1 319  ? 134.032 115.843 83.424  1.00 41.08  ? 319  CYS   C O     1 
ATOM   1336 C CB    . CYS   A 1 319  ? 134.927 115.152 81.016  1.00 51.20  ? 319  CYS   C CB    1 
ATOM   1337 S SG    . CYS   A 1 319  ? 133.227 114.558 80.948  1.00 56.26  ? 319  CYS   C SG    1 
ATOM   1338 N N     . THR   A 1 320  ? 133.898 118.041 82.984  1.00 45.03  ? 320  THR   C N     1 
ATOM   1339 C CA    . THR   A 1 320  ? 133.033 118.315 84.116  1.00 43.59  ? 320  THR   C CA    1 
ATOM   1340 C C     . THR   A 1 320  ? 131.605 118.019 83.690  1.00 42.92  ? 320  THR   C C     1 
ATOM   1341 O O     . THR   A 1 320  ? 131.351 117.820 82.503  1.00 45.70  ? 320  THR   C O     1 
ATOM   1342 C CB    . THR   A 1 320  ? 133.164 119.771 84.586  1.00 43.04  ? 320  THR   C CB    1 
ATOM   1343 O OG1   . THR   A 1 320  ? 132.766 120.648 83.525  1.00 46.71  ? 320  THR   C OG1   1 
ATOM   1344 C CG2   . THR   A 1 320  ? 134.603 120.064 84.976  1.00 43.15  ? 320  THR   C CG2   1 
ATOM   1345 N N     . ASP   A 1 321  ? 130.685 117.985 84.650  1.00 42.95  ? 321  ASP   C N     1 
ATOM   1346 C CA    . ASP   A 1 321  ? 129.280 117.659 84.390  1.00 46.33  ? 321  ASP   C CA    1 
ATOM   1347 C C     . ASP   A 1 321  ? 129.095 116.153 84.265  1.00 47.86  ? 321  ASP   C C     1 
ATOM   1348 O O     . ASP   A 1 321  ? 129.364 115.556 83.224  1.00 47.91  ? 321  ASP   C O     1 
ATOM   1349 C CB    . ASP   A 1 321  ? 128.740 118.354 83.131  1.00 51.87  ? 321  ASP   C CB    1 
ATOM   1350 C CG    . ASP   A 1 321  ? 127.210 118.360 83.082  1.00 54.48  ? 321  ASP   C CG    1 
ATOM   1351 O OD1   . ASP   A 1 321  ? 126.609 118.269 84.129  1.00 52.49  ? 321  ASP   C OD1   1 
ATOM   1352 O OD2   . ASP   A 1 321  ? 126.659 118.444 82.008  1.00 51.29  ? 321  ASP   C OD2   1 
ATOM   1353 N N     . TRP   A 1 322  ? 128.634 115.540 85.346  1.00 43.23  ? 322  TRP   C N     1 
ATOM   1354 C CA    . TRP   A 1 322  ? 128.455 114.095 85.434  1.00 41.48  ? 322  TRP   C CA    1 
ATOM   1355 C C     . TRP   A 1 322  ? 127.562 113.519 84.334  1.00 43.57  ? 322  TRP   C C     1 
ATOM   1356 O O     . TRP   A 1 322  ? 127.618 112.325 84.037  1.00 44.91  ? 322  TRP   C O     1 
ATOM   1357 C CB    . TRP   A 1 322  ? 127.905 113.736 86.820  1.00 40.57  ? 322  TRP   C CB    1 
ATOM   1358 C CG    . TRP   A 1 322  ? 126.557 114.270 87.106  1.00 43.67  ? 322  TRP   C CG    1 
ATOM   1359 C CD1   . TRP   A 1 322  ? 126.258 115.462 87.683  1.00 43.95  ? 322  TRP   C CD1   1 
ATOM   1360 C CD2   . TRP   A 1 322  ? 125.300 113.610 86.876  1.00 44.51  ? 322  TRP   C CD2   1 
ATOM   1361 N NE1   . TRP   A 1 322  ? 124.904 115.598 87.803  1.00 45.14  ? 322  TRP   C NE1   1 
ATOM   1362 C CE2   . TRP   A 1 322  ? 124.301 114.479 87.304  1.00 44.77  ? 322  TRP   C CE2   1 
ATOM   1363 C CE3   . TRP   A 1 322  ? 124.943 112.383 86.313  1.00 45.60  ? 322  TRP   C CE3   1 
ATOM   1364 C CZ2   . TRP   A 1 322  ? 122.966 114.147 87.229  1.00 48.53  ? 322  TRP   C CZ2   1 
ATOM   1365 C CZ3   . TRP   A 1 322  ? 123.607 112.055 86.233  1.00 47.56  ? 322  TRP   C CZ3   1 
ATOM   1366 C CH2   . TRP   A 1 322  ? 122.643 112.918 86.669  1.00 49.73  ? 322  TRP   C CH2   1 
ATOM   1367 N N     . GLN   A 1 323  ? 126.739 114.363 83.721  1.00 45.83  ? 323  GLN   C N     1 
ATOM   1368 C CA    . GLN   A 1 323  ? 125.820 113.910 82.682  1.00 46.67  ? 323  GLN   C CA    1 
ATOM   1369 C C     . GLN   A 1 323  ? 126.485 113.794 81.308  1.00 48.87  ? 323  GLN   C C     1 
ATOM   1370 O O     . GLN   A 1 323  ? 125.873 113.293 80.364  1.00 51.34  ? 323  GLN   C O     1 
ATOM   1371 C CB    . GLN   A 1 323  ? 124.623 114.859 82.591  1.00 50.02  ? 323  GLN   C CB    1 
ATOM   1372 C CG    . GLN   A 1 323  ? 123.770 114.878 83.837  1.00 50.02  ? 323  GLN   C CG    1 
ATOM   1373 C CD    . GLN   A 1 323  ? 122.607 115.835 83.752  1.00 52.58  ? 323  GLN   C CD    1 
ATOM   1374 O OE1   . GLN   A 1 323  ? 121.729 115.694 82.897  1.00 55.73  ? 323  GLN   C OE1   1 
ATOM   1375 N NE2   . GLN   A 1 323  ? 122.591 116.822 84.640  1.00 49.45  ? 323  GLN   C NE2   1 
ATOM   1376 N N     . LYS   A 1 324  ? 127.728 114.261 81.190  1.00 49.34  ? 324  LYS   C N     1 
ATOM   1377 C CA    . LYS   A 1 324  ? 128.441 114.217 79.917  1.00 49.16  ? 324  LYS   C CA    1 
ATOM   1378 C C     . LYS   A 1 324  ? 129.257 112.940 79.773  1.00 47.54  ? 324  LYS   C C     1 
ATOM   1379 O O     . LYS   A 1 324  ? 130.029 112.585 80.661  1.00 48.10  ? 324  LYS   C O     1 
ATOM   1380 C CB    . LYS   A 1 324  ? 129.356 115.432 79.765  1.00 50.64  ? 324  LYS   C CB    1 
ATOM   1381 C CG    . LYS   A 1 324  ? 130.091 115.483 78.429  1.00 54.70  ? 324  LYS   C CG    1 
ATOM   1382 C CD    . LYS   A 1 324  ? 130.898 116.757 78.281  1.00 57.56  ? 324  LYS   C CD    1 
ATOM   1383 C CE    . LYS   A 1 324  ? 131.646 116.778 76.958  1.00 59.37  ? 324  LYS   C CE    1 
ATOM   1384 N NZ    . LYS   A 1 324  ? 132.394 118.044 76.767  1.00 59.42  ? 324  LYS   C NZ    1 
ATOM   1385 N N     . ALA   A 1 325  ? 129.089 112.252 78.645  1.00 47.46  ? 325  ALA   C N     1 
ATOM   1386 C CA    . ALA   A 1 325  ? 129.825 111.014 78.409  1.00 50.79  ? 325  ALA   C CA    1 
ATOM   1387 C C     . ALA   A 1 325  ? 131.178 111.286 77.770  1.00 52.86  ? 325  ALA   C C     1 
ATOM   1388 O O     . ALA   A 1 325  ? 131.276 112.027 76.792  1.00 56.21  ? 325  ALA   C O     1 
ATOM   1389 C CB    . ALA   A 1 325  ? 129.012 110.080 77.525  1.00 48.69  ? 325  ALA   C CB    1 
ATOM   1390 N N     . GLU   A 1 326  ? 132.207 110.638 78.303  1.00 48.98  ? 326  GLU   C N     1 
ATOM   1391 C CA    . GLU   A 1 326  ? 133.568 110.767 77.798  1.00 48.02  ? 326  GLU   C CA    1 
ATOM   1392 C C     . GLU   A 1 326  ? 134.358 109.488 77.984  1.00 48.52  ? 326  GLU   C C     1 
ATOM   1393 O O     . GLU   A 1 326  ? 133.865 108.510 78.545  1.00 47.46  ? 326  GLU   C O     1 
ATOM   1394 C CB    . GLU   A 1 326  ? 134.306 111.914 78.481  1.00 47.44  ? 326  GLU   C CB    1 
ATOM   1395 C CG    . GLU   A 1 326  ? 134.325 113.199 77.690  1.00 53.93  ? 326  GLU   C CG    1 
ATOM   1396 C CD    . GLU   A 1 326  ? 135.196 113.109 76.463  1.00 56.91  ? 326  GLU   C CD    1 
ATOM   1397 O OE1   . GLU   A 1 326  ? 135.883 112.118 76.307  1.00 54.18  ? 326  GLU   C OE1   1 
ATOM   1398 O OE2   . GLU   A 1 326  ? 135.184 114.034 75.685  1.00 59.64  ? 326  GLU   C OE2   1 
ATOM   1399 N N     . ARG   A 1 327  ? 135.591 109.500 77.508  1.00 49.30  ? 327  ARG   C N     1 
ATOM   1400 C CA    . ARG   A 1 327  ? 136.441 108.325 77.600  1.00 46.92  ? 327  ARG   C CA    1 
ATOM   1401 C C     . ARG   A 1 327  ? 136.623 107.899 79.053  1.00 43.70  ? 327  ARG   C C     1 
ATOM   1402 O O     . ARG   A 1 327  ? 136.721 108.736 79.953  1.00 42.56  ? 327  ARG   C O     1 
ATOM   1403 C CB    . ARG   A 1 327  ? 137.804 108.590 76.990  1.00 47.45  ? 327  ARG   C CB    1 
ATOM   1404 C CG    . ARG   A 1 327  ? 137.826 108.859 75.501  1.00 48.73  ? 327  ARG   C CG    1 
ATOM   1405 C CD    . ARG   A 1 327  ? 139.205 109.190 75.037  1.00 49.97  ? 327  ARG   C CD    1 
ATOM   1406 N NE    . ARG   A 1 327  ? 140.145 108.104 75.315  1.00 49.72  ? 327  ARG   C NE    1 
ATOM   1407 C CZ    . ARG   A 1 327  ? 140.325 107.020 74.531  1.00 54.55  ? 327  ARG   C CZ    1 
ATOM   1408 N NH1   . ARG   A 1 327  ? 139.629 106.878 73.421  1.00 52.72  ? 327  ARG   C NH1   1 
ATOM   1409 N NH2   . ARG   A 1 327  ? 141.202 106.095 74.884  1.00 55.20  ? 327  ARG   C NH2   1 
ATOM   1410 N N     . GLY   A 1 328  ? 136.678 106.590 79.278  1.00 42.03  ? 328  GLY   C N     1 
ATOM   1411 C CA    . GLY   A 1 328  ? 136.849 106.048 80.623  1.00 38.19  ? 328  GLY   C CA    1 
ATOM   1412 C C     . GLY   A 1 328  ? 138.088 106.596 81.334  1.00 38.41  ? 328  GLY   C C     1 
ATOM   1413 O O     . GLY   A 1 328  ? 138.069 106.797 82.549  1.00 40.34  ? 328  GLY   C O     1 
ATOM   1414 N N     . ASP   A 1 329  ? 139.162 106.849 80.590  1.00 38.68  ? 329  ASP   C N     1 
ATOM   1415 C CA    . ASP   A 1 329  ? 140.390 107.356 81.196  1.00 36.60  ? 329  ASP   C CA    1 
ATOM   1416 C C     . ASP   A 1 329  ? 140.209 108.791 81.663  1.00 37.49  ? 329  ASP   C C     1 
ATOM   1417 O O     . ASP   A 1 329  ? 140.642 109.161 82.757  1.00 38.25  ? 329  ASP   C O     1 
ATOM   1418 C CB    . ASP   A 1 329  ? 141.540 107.254 80.195  1.00 36.24  ? 329  ASP   C CB    1 
ATOM   1419 C CG    . ASP   A 1 329  ? 141.183 107.886 78.867  1.00 43.26  ? 329  ASP   C CG    1 
ATOM   1420 O OD1   . ASP   A 1 329  ? 140.040 108.248 78.708  1.00 45.34  ? 329  ASP   C OD1   1 
ATOM   1421 O OD2   . ASP   A 1 329  ? 142.029 107.987 78.010  1.00 46.53  ? 329  ASP   C OD2   1 
ATOM   1422 N N     . ILE   A 1 330  ? 139.512 109.582 80.861  1.00 40.09  ? 330  ILE   C N     1 
ATOM   1423 C CA    . ILE   A 1 330  ? 139.217 110.962 81.214  1.00 38.30  ? 330  ILE   C CA    1 
ATOM   1424 C C     . ILE   A 1 330  ? 138.349 111.020 82.455  1.00 37.35  ? 330  ILE   C C     1 
ATOM   1425 O O     . ILE   A 1 330  ? 138.588 111.829 83.353  1.00 36.67  ? 330  ILE   C O     1 
ATOM   1426 C CB    . ILE   A 1 330  ? 138.506 111.701 80.066  1.00 40.77  ? 330  ILE   C CB    1 
ATOM   1427 C CG1   . ILE   A 1 330  ? 139.481 111.889 78.890  1.00 44.41  ? 330  ILE   C CG1   1 
ATOM   1428 C CG2   . ILE   A 1 330  ? 137.941 113.040 80.560  1.00 44.78  ? 330  ILE   C CG2   1 
ATOM   1429 C CD1   . ILE   A 1 330  ? 138.829 112.381 77.619  1.00 47.60  ? 330  ILE   C CD1   1 
ATOM   1430 N N     . LEU   A 1 331  ? 137.335 110.165 82.501  1.00 37.07  ? 331  LEU   C N     1 
ATOM   1431 C CA    . LEU   A 1 331  ? 136.405 110.151 83.616  1.00 33.75  ? 331  LEU   C CA    1 
ATOM   1432 C C     . LEU   A 1 331  ? 137.104 109.771 84.923  1.00 36.06  ? 331  LEU   C C     1 
ATOM   1433 O O     . LEU   A 1 331  ? 136.863 110.393 85.960  1.00 32.77  ? 331  LEU   C O     1 
ATOM   1434 C CB    . LEU   A 1 331  ? 135.259 109.181 83.305  1.00 32.35  ? 331  LEU   C CB    1 
ATOM   1435 C CG    . LEU   A 1 331  ? 134.133 109.067 84.341  1.00 33.84  ? 331  LEU   C CG    1 
ATOM   1436 C CD1   . LEU   A 1 331  ? 133.461 110.423 84.534  1.00 36.79  ? 331  LEU   C CD1   1 
ATOM   1437 C CD2   . LEU   A 1 331  ? 133.128 108.039 83.846  1.00 36.09  ? 331  LEU   C CD2   1 
ATOM   1438 N N     . LEU   A 1 332  ? 137.988 108.772 84.877  1.00 36.16  ? 332  LEU   C N     1 
ATOM   1439 C CA    . LEU   A 1 332  ? 138.717 108.376 86.079  1.00 28.68  ? 332  LEU   C CA    1 
ATOM   1440 C C     . LEU   A 1 332  ? 139.637 109.490 86.562  1.00 31.66  ? 332  LEU   C C     1 
ATOM   1441 O O     . LEU   A 1 332  ? 139.707 109.763 87.761  1.00 32.91  ? 332  LEU   C O     1 
ATOM   1442 C CB    . LEU   A 1 332  ? 139.545 107.118 85.812  1.00 26.55  ? 332  LEU   C CB    1 
ATOM   1443 C CG    . LEU   A 1 332  ? 138.765 105.810 85.622  1.00 28.69  ? 332  LEU   C CG    1 
ATOM   1444 C CD1   . LEU   A 1 332  ? 139.714 104.763 85.096  1.00 34.31  ? 332  LEU   C CD1   1 
ATOM   1445 C CD2   . LEU   A 1 332  ? 138.161 105.361 86.950  1.00 32.78  ? 332  LEU   C CD2   1 
ATOM   1446 N N     . SER   A 1 333  ? 140.312 110.165 85.630  1.00 32.14  ? 333  SER   C N     1 
ATOM   1447 C CA    . SER   A 1 333  ? 141.187 111.271 86.002  1.00 29.27  ? 333  SER   C CA    1 
ATOM   1448 C C     . SER   A 1 333  ? 140.389 112.432 86.580  1.00 31.23  ? 333  SER   C C     1 
ATOM   1449 O O     . SER   A 1 333  ? 140.827 113.085 87.528  1.00 31.33  ? 333  SER   C O     1 
ATOM   1450 C CB    . SER   A 1 333  ? 141.993 111.743 84.805  1.00 29.34  ? 333  SER   C CB    1 
ATOM   1451 O OG    . SER   A 1 333  ? 142.937 110.782 84.422  1.00 32.78  ? 333  SER   C OG    1 
ATOM   1452 N N     . SER   A 1 334  ? 139.206 112.673 86.025  1.00 31.12  ? 334  SER   C N     1 
ATOM   1453 C CA    . SER   A 1 334  ? 138.349 113.754 86.485  1.00 30.25  ? 334  SER   C CA    1 
ATOM   1454 C C     . SER   A 1 334  ? 137.925 113.547 87.937  1.00 29.18  ? 334  SER   C C     1 
ATOM   1455 O O     . SER   A 1 334  ? 137.905 114.493 88.731  1.00 31.17  ? 334  SER   C O     1 
ATOM   1456 C CB    . SER   A 1 334  ? 137.136 113.861 85.595  1.00 34.27  ? 334  SER   C CB    1 
ATOM   1457 O OG    . SER   A 1 334  ? 136.359 114.964 85.944  1.00 36.92  ? 334  SER   C OG    1 
ATOM   1458 N N     . LEU   A 1 335  ? 137.591 112.307 88.304  1.00 29.85  ? 335  LEU   C N     1 
ATOM   1459 C CA    . LEU   A 1 335  ? 137.223 112.039 89.692  1.00 26.48  ? 335  LEU   C CA    1 
ATOM   1460 C C     . LEU   A 1 335  ? 138.424 112.187 90.624  1.00 26.64  ? 335  LEU   C C     1 
ATOM   1461 O O     . LEU   A 1 335  ? 138.317 112.790 91.691  1.00 29.59  ? 335  LEU   C O     1 
ATOM   1462 C CB    . LEU   A 1 335  ? 136.643 110.621 89.843  1.00 23.76  ? 335  LEU   C CB    1 
ATOM   1463 C CG    . LEU   A 1 335  ? 135.249 110.368 89.222  1.00 26.23  ? 335  LEU   C CG    1 
ATOM   1464 C CD1   . LEU   A 1 335  ? 134.948 108.872 89.247  1.00 23.31  ? 335  LEU   C CD1   1 
ATOM   1465 C CD2   . LEU   A 1 335  ? 134.178 111.133 90.015  1.00 29.08  ? 335  LEU   C CD2   1 
ATOM   1466 N N     . ILE   A 1 336  ? 139.581 111.676 90.211  1.00 25.84  ? 336  ILE   C N     1 
ATOM   1467 C CA    . ILE   A 1 336  ? 140.768 111.713 91.062  1.00 22.16  ? 336  ILE   C CA    1 
ATOM   1468 C C     . ILE   A 1 336  ? 141.232 113.143 91.312  1.00 25.28  ? 336  ILE   C C     1 
ATOM   1469 O O     . ILE   A 1 336  ? 141.638 113.484 92.422  1.00 25.61  ? 336  ILE   C O     1 
ATOM   1470 C CB    . ILE   A 1 336  ? 141.919 110.879 90.470  1.00 21.41  ? 336  ILE   C CB    1 
ATOM   1471 C CG1   . ILE   A 1 336  ? 141.529 109.398 90.457  1.00 20.77  ? 336  ILE   C CG1   1 
ATOM   1472 C CG2   . ILE   A 1 336  ? 143.179 111.068 91.320  1.00 24.43  ? 336  ILE   C CG2   1 
ATOM   1473 C CD1   . ILE   A 1 336  ? 142.442 108.527 89.624  1.00 21.08  ? 336  ILE   C CD1   1 
ATOM   1474 N N     . ARG   A 1 337  ? 141.180 113.974 90.274  1.00 27.90  ? 337  ARG   C N     1 
ATOM   1475 C CA    . ARG   A 1 337  ? 141.636 115.359 90.354  1.00 28.91  ? 337  ARG   C CA    1 
ATOM   1476 C C     . ARG   A 1 337  ? 140.570 116.307 90.907  1.00 30.36  ? 337  ARG   C C     1 
ATOM   1477 O O     . ARG   A 1 337  ? 140.789 117.517 90.972  1.00 32.32  ? 337  ARG   C O     1 
ATOM   1478 C CB    . ARG   A 1 337  ? 142.064 115.852 88.979  1.00 29.78  ? 337  ARG   C CB    1 
ATOM   1479 C CG    . ARG   A 1 337  ? 143.288 115.162 88.406  1.00 29.82  ? 337  ARG   C CG    1 
ATOM   1480 C CD    . ARG   A 1 337  ? 143.581 115.624 87.026  1.00 29.03  ? 337  ARG   C CD    1 
ATOM   1481 N NE    . ARG   A 1 337  ? 144.003 117.019 86.989  1.00 34.56  ? 337  ARG   C NE    1 
ATOM   1482 C CZ    . ARG   A 1 337  ? 145.279 117.443 87.133  1.00 37.26  ? 337  ARG   C CZ    1 
ATOM   1483 N NH1   . ARG   A 1 337  ? 146.252 116.580 87.317  1.00 34.94  ? 337  ARG   C NH1   1 
ATOM   1484 N NH2   . ARG   A 1 337  ? 145.555 118.735 87.088  1.00 39.87  ? 337  ARG   C NH2   1 
ATOM   1485 N N     . LYS   A 1 338  ? 139.422 115.759 91.303  1.00 28.81  ? 338  LYS   C N     1 
ATOM   1486 C CA    . LYS   A 1 338  ? 138.324 116.535 91.874  1.00 25.91  ? 338  LYS   C CA    1 
ATOM   1487 C C     . LYS   A 1 338  ? 137.781 117.612 90.950  1.00 26.17  ? 338  LYS   C C     1 
ATOM   1488 O O     . LYS   A 1 338  ? 137.456 118.713 91.398  1.00 28.95  ? 338  LYS   C O     1 
ATOM   1489 C CB    . LYS   A 1 338  ? 138.759 117.172 93.196  1.00 25.46  ? 338  LYS   C CB    1 
ATOM   1490 C CG    . LYS   A 1 338  ? 139.327 116.187 94.195  1.00 26.41  ? 338  LYS   C CG    1 
ATOM   1491 C CD    . LYS   A 1 338  ? 138.273 115.194 94.637  1.00 19.66  ? 338  LYS   C CD    1 
ATOM   1492 C CE    . LYS   A 1 338  ? 138.829 114.208 95.614  1.00 18.27  ? 338  LYS   C CE    1 
ATOM   1493 N NZ    . LYS   A 1 338  ? 137.813 113.220 96.009  1.00 20.66  ? 338  LYS   C NZ    1 
ATOM   1494 N N     . LYS   A 1 339  ? 137.638 117.288 89.671  1.00 28.45  ? 339  LYS   C N     1 
ATOM   1495 C CA    . LYS   A 1 339  ? 137.011 118.217 88.744  1.00 28.49  ? 339  LYS   C CA    1 
ATOM   1496 C C     . LYS   A 1 339  ? 135.555 117.822 88.587  1.00 29.17  ? 339  LYS   C C     1 
ATOM   1497 O O     . LYS   A 1 339  ? 134.680 118.662 88.375  1.00 32.62  ? 339  LYS   C O     1 
ATOM   1498 C CB    . LYS   A 1 339  ? 137.729 118.213 87.395  1.00 32.34  ? 339  LYS   C CB    1 
ATOM   1499 C CG    . LYS   A 1 339  ? 139.210 118.576 87.473  1.00 33.25  ? 339  LYS   C CG    1 
ATOM   1500 C CD    . LYS   A 1 339  ? 139.421 119.966 88.065  1.00 34.12  ? 339  LYS   C CD    1 
ATOM   1501 C CE    . LYS   A 1 339  ? 140.887 120.365 88.037  1.00 35.42  ? 339  LYS   C CE    1 
ATOM   1502 N NZ    . LYS   A 1 339  ? 141.110 121.697 88.672  1.00 33.29  ? 339  LYS   C NZ    1 
ATOM   1503 N N     . LEU   A 1 340  ? 135.301 116.529 88.730  1.00 28.65  ? 340  LEU   C N     1 
ATOM   1504 C CA    . LEU   A 1 340  ? 133.955 115.992 88.664  1.00 27.23  ? 340  LEU   C CA    1 
ATOM   1505 C C     . LEU   A 1 340  ? 133.423 115.743 90.068  1.00 30.49  ? 340  LEU   C C     1 
ATOM   1506 O O     . LEU   A 1 340  ? 134.068 115.080 90.878  1.00 30.99  ? 340  LEU   C O     1 
ATOM   1507 C CB    . LEU   A 1 340  ? 133.945 114.710 87.832  1.00 25.11  ? 340  LEU   C CB    1 
ATOM   1508 C CG    . LEU   A 1 340  ? 132.637 113.948 87.767  1.00 29.56  ? 340  LEU   C CG    1 
ATOM   1509 C CD1   . LEU   A 1 340  ? 131.581 114.808 87.121  1.00 38.13  ? 340  LEU   C CD1   1 
ATOM   1510 C CD2   . LEU   A 1 340  ? 132.850 112.702 86.953  1.00 32.46  ? 340  LEU   C CD2   1 
ATOM   1511 N N     . LEU   A 1 341  ? 132.266 116.325 90.370  1.00 29.92  ? 341  LEU   C N     1 
ATOM   1512 C CA    . LEU   A 1 341  ? 131.681 116.262 91.706  1.00 25.84  ? 341  LEU   C CA    1 
ATOM   1513 C C     . LEU   A 1 341  ? 132.665 116.691 92.799  1.00 25.10  ? 341  LEU   C C     1 
ATOM   1514 O O     . LEU   A 1 341  ? 133.084 115.866 93.614  1.00 25.88  ? 341  LEU   C O     1 
ATOM   1515 C CB    . LEU   A 1 341  ? 131.187 114.842 92.013  1.00 23.61  ? 341  LEU   C CB    1 
ATOM   1516 C CG    . LEU   A 1 341  ? 130.096 114.267 91.092  1.00 28.88  ? 341  LEU   C CG    1 
ATOM   1517 C CD1   . LEU   A 1 341  ? 129.853 112.823 91.478  1.00 27.00  ? 341  LEU   C CD1   1 
ATOM   1518 C CD2   . LEU   A 1 341  ? 128.814 115.076 91.233  1.00 30.80  ? 341  LEU   C CD2   1 
ATOM   1519 N N     . PRO   A 1 342  ? 133.031 117.979 92.851  1.00 26.60  ? 342  PRO   C N     1 
ATOM   1520 C CA    . PRO   A 1 342  ? 133.932 118.563 93.818  1.00 26.11  ? 342  PRO   C CA    1 
ATOM   1521 C C     . PRO   A 1 342  ? 133.423 118.296 95.219  1.00 25.70  ? 342  PRO   C C     1 
ATOM   1522 O O     . PRO   A 1 342  ? 132.217 118.207 95.438  1.00 28.13  ? 342  PRO   C O     1 
ATOM   1523 C CB    . PRO   A 1 342  ? 133.872 120.057 93.481  1.00 32.20  ? 342  PRO   C CB    1 
ATOM   1524 C CG    . PRO   A 1 342  ? 133.460 120.105 92.037  1.00 31.85  ? 342  PRO   C CG    1 
ATOM   1525 C CD    . PRO   A 1 342  ? 132.513 118.943 91.865  1.00 30.56  ? 342  PRO   C CD    1 
ATOM   1526 N N     . GLU   A 1 343  ? 134.351 118.159 96.152  1.00 25.50  ? 343  GLU   C N     1 
ATOM   1527 C CA    . GLU   A 1 343  ? 134.068 117.900 97.562  1.00 29.35  ? 343  GLU   C CA    1 
ATOM   1528 C C     . GLU   A 1 343  ? 133.577 116.482 97.851  1.00 27.52  ? 343  GLU   C C     1 
ATOM   1529 O O     . GLU   A 1 343  ? 133.393 116.120 99.012  1.00 26.86  ? 343  GLU   C O     1 
ATOM   1530 C CB    . GLU   A 1 343  ? 133.057 118.912 98.115  1.00 33.38  ? 343  GLU   C CB    1 
ATOM   1531 C CG    . GLU   A 1 343  ? 133.488 120.368 97.969  1.00 42.97  ? 343  GLU   C CG    1 
ATOM   1532 C CD    . GLU   A 1 343  ? 134.717 120.681 98.778  1.00 68.33  ? 343  GLU   C CD    1 
ATOM   1533 O OE1   . GLU   A 1 343  ? 134.886 120.082 99.818  1.00 46.84  ? 343  GLU   C OE1   1 
ATOM   1534 O OE2   . GLU   A 1 343  ? 135.489 121.511 98.358  1.00 54.66  ? 343  GLU   C OE2   1 
ATOM   1535 N N     . ALA   A 1 344  ? 133.419 115.652 96.824  1.00 22.81  ? 344  ALA   C N     1 
ATOM   1536 C CA    . ALA   A 1 344  ? 133.133 114.247 97.070  1.00 16.52  ? 344  ALA   C CA    1 
ATOM   1537 C C     . ALA   A 1 344  ? 134.398 113.601 97.613  1.00 16.13  ? 344  ALA   C C     1 
ATOM   1538 O O     . ALA   A 1 344  ? 135.501 113.985 97.218  1.00 22.49  ? 344  ALA   C O     1 
ATOM   1539 C CB    . ALA   A 1 344  ? 132.661 113.557 95.799  1.00 16.37  ? 344  ALA   C CB    1 
ATOM   1540 N N     . SER   A 1 345  ? 134.253 112.640 98.515  1.00 12.16  ? 345  SER   C N     1 
ATOM   1541 C CA    . SER   A 1 345  ? 135.420 111.974 99.076  1.00 10.72  ? 345  SER   C CA    1 
ATOM   1542 C C     . SER   A 1 345  ? 135.839 110.810 98.189  1.00 9.69   ? 345  SER   C C     1 
ATOM   1543 O O     . SER   A 1 345  ? 135.022 110.267 97.441  1.00 10.12  ? 345  SER   C O     1 
ATOM   1544 C CB    . SER   A 1 345  ? 135.131 111.503 100.485 1.00 12.35  ? 345  SER   C CB    1 
ATOM   1545 O OG    . SER   A 1 345  ? 134.872 112.586 101.334 1.00 15.20  ? 345  SER   C OG    1 
ATOM   1546 N N     . LEU   A 1 346  ? 137.112 110.435 98.261  1.00 9.26   ? 346  LEU   C N     1 
ATOM   1547 C CA    . LEU   A 1 346  ? 137.621 109.334 97.449  1.00 9.52   ? 346  LEU   C CA    1 
ATOM   1548 C C     . LEU   A 1 346  ? 138.686 108.508 98.166  1.00 7.62   ? 346  LEU   C C     1 
ATOM   1549 O O     . LEU   A 1 346  ? 139.675 109.045 98.665  1.00 12.74  ? 346  LEU   C O     1 
ATOM   1550 C CB    . LEU   A 1 346  ? 138.198 109.898 96.142  1.00 9.16   ? 346  LEU   C CB    1 
ATOM   1551 C CG    . LEU   A 1 346  ? 138.871 108.906 95.183  1.00 10.79  ? 346  LEU   C CG    1 
ATOM   1552 C CD1   . LEU   A 1 346  ? 137.855 107.926 94.633  1.00 11.23  ? 346  LEU   C CD1   1 
ATOM   1553 C CD2   . LEU   A 1 346  ? 139.515 109.682 94.049  1.00 15.81  ? 346  LEU   C CD2   1 
ATOM   1554 N N     . LEU   A 1 347  ? 138.490 107.195 98.179  1.00 1.89   ? 347  LEU   C N     1 
ATOM   1555 C CA    . LEU   A 1 347  ? 139.466 106.260 98.719  1.00 0.01   ? 347  LEU   C CA    1 
ATOM   1556 C C     . LEU   A 1 347  ? 140.061 105.440 97.586  1.00 0.05   ? 347  LEU   C C     1 
ATOM   1557 O O     . LEU   A 1 347  ? 139.327 104.836 96.806  1.00 15.28  ? 347  LEU   C O     1 
ATOM   1558 C CB    . LEU   A 1 347  ? 138.804 105.330 99.745  1.00 0.08   ? 347  LEU   C CB    1 
ATOM   1559 C CG    . LEU   A 1 347  ? 139.684 104.214 100.332 1.00 0.04   ? 347  LEU   C CG    1 
ATOM   1560 C CD1   . LEU   A 1 347  ? 140.786 104.817 101.167 1.00 0.06   ? 347  LEU   C CD1   1 
ATOM   1561 C CD2   . LEU   A 1 347  ? 138.826 103.297 101.170 1.00 0.05   ? 347  LEU   C CD2   1 
ATOM   1562 N N     . ILE   A 1 348  ? 141.382 105.430 97.481  1.00 0.51   ? 348  ILE   C N     1 
ATOM   1563 C CA    . ILE   A 1 348  ? 142.061 104.709 96.406  1.00 0.21   ? 348  ILE   C CA    1 
ATOM   1564 C C     . ILE   A 1 348  ? 142.948 103.604 96.947  1.00 0.19   ? 348  ILE   C C     1 
ATOM   1565 O O     . ILE   A 1 348  ? 143.692 103.821 97.899  1.00 0.00   ? 348  ILE   C O     1 
ATOM   1566 C CB    . ILE   A 1 348  ? 142.935 105.659 95.560  1.00 1.58   ? 348  ILE   C CB    1 
ATOM   1567 C CG1   . ILE   A 1 348  ? 142.071 106.727 94.920  1.00 10.86  ? 348  ILE   C CG1   1 
ATOM   1568 C CG2   . ILE   A 1 348  ? 143.699 104.869 94.497  1.00 10.84  ? 348  ILE   C CG2   1 
ATOM   1569 C CD1   . ILE   A 1 348  ? 142.857 107.871 94.336  1.00 11.64  ? 348  ILE   C CD1   1 
ATOM   1570 N N     . THR   A 1 349  ? 142.885 102.426 96.336  1.00 3.82   ? 349  THR   C N     1 
ATOM   1571 C CA    . THR   A 1 349  ? 143.804 101.355 96.707  1.00 0.48   ? 349  THR   C CA    1 
ATOM   1572 C C     . THR   A 1 349  ? 144.760 101.109 95.547  1.00 6.70   ? 349  THR   C C     1 
ATOM   1573 O O     . THR   A 1 349  ? 144.344 101.092 94.386  1.00 9.71   ? 349  THR   C O     1 
ATOM   1574 C CB    . THR   A 1 349  ? 143.064 100.052 97.048  1.00 12.17  ? 349  THR   C CB    1 
ATOM   1575 O OG1   . THR   A 1 349  ? 142.382 99.589  95.889  1.00 14.27  ? 349  THR   C OG1   1 
ATOM   1576 C CG2   . THR   A 1 349  ? 142.050 100.287 98.168  1.00 14.56  ? 349  THR   C CG2   1 
ATOM   1577 N N     . THR   A 1 350  ? 146.045 100.937 95.850  1.00 6.91   ? 350  THR   C N     1 
ATOM   1578 C CA    . THR   A 1 350  ? 147.035 100.752 94.793  1.00 7.79   ? 350  THR   C CA    1 
ATOM   1579 C C     . THR   A 1 350  ? 148.309 100.052 95.253  1.00 8.74   ? 350  THR   C C     1 
ATOM   1580 O O     . THR   A 1 350  ? 148.675 100.103 96.425  1.00 11.92  ? 350  THR   C O     1 
ATOM   1581 C CB    . THR   A 1 350  ? 147.418 102.112 94.190  1.00 8.17   ? 350  THR   C CB    1 
ATOM   1582 O OG1   . THR   A 1 350  ? 148.234 101.905 93.043  1.00 14.91  ? 350  THR   C OG1   1 
ATOM   1583 C CG2   . THR   A 1 350  ? 148.181 102.949 95.205  1.00 6.23   ? 350  THR   C CG2   1 
ATOM   1584 N N     . ARG   A 1 351  ? 149.011 99.439  94.313  1.00 10.21  ? 351  ARG   C N     1 
ATOM   1585 C CA    . ARG   A 1 351  ? 150.345 98.918  94.587  1.00 9.74   ? 351  ARG   C CA    1 
ATOM   1586 C C     . ARG   A 1 351  ? 151.330 100.091 94.590  1.00 11.28  ? 351  ARG   C C     1 
ATOM   1587 O O     . ARG   A 1 351  ? 151.207 100.975 93.747  1.00 17.12  ? 351  ARG   C O     1 
ATOM   1588 C CB    . ARG   A 1 351  ? 150.761 97.916  93.529  1.00 10.39  ? 351  ARG   C CB    1 
ATOM   1589 C CG    . ARG   A 1 351  ? 149.996 96.621  93.533  1.00 10.79  ? 351  ARG   C CG    1 
ATOM   1590 C CD    . ARG   A 1 351  ? 150.184 95.878  92.264  1.00 11.66  ? 351  ARG   C CD    1 
ATOM   1591 N NE    . ARG   A 1 351  ? 151.537 95.401  92.088  1.00 10.04  ? 351  ARG   C NE    1 
ATOM   1592 C CZ    . ARG   A 1 351  ? 152.001 94.857  90.946  1.00 10.11  ? 351  ARG   C CZ    1 
ATOM   1593 N NH1   . ARG   A 1 351  ? 151.206 94.735  89.905  1.00 11.06  ? 351  ARG   C NH1   1 
ATOM   1594 N NH2   . ARG   A 1 351  ? 153.250 94.446  90.872  1.00 12.34  ? 351  ARG   C NH2   1 
ATOM   1595 N N     . PRO   A 1 352  ? 152.332 100.120 95.477  1.00 9.46   ? 352  PRO   C N     1 
ATOM   1596 C CA    . PRO   A 1 352  ? 153.341 101.162 95.584  1.00 9.41   ? 352  PRO   C CA    1 
ATOM   1597 C C     . PRO   A 1 352  ? 153.975 101.507 94.237  1.00 13.49  ? 352  PRO   C C     1 
ATOM   1598 O O     . PRO   A 1 352  ? 154.258 102.668 93.955  1.00 16.96  ? 352  PRO   C O     1 
ATOM   1599 C CB    . PRO   A 1 352  ? 154.360 100.515 96.527  1.00 10.70  ? 352  PRO   C CB    1 
ATOM   1600 C CG    . PRO   A 1 352  ? 153.534 99.606  97.393  1.00 12.43  ? 352  PRO   C CG    1 
ATOM   1601 C CD    . PRO   A 1 352  ? 152.470 99.048  96.466  1.00 11.38  ? 352  PRO   C CD    1 
ATOM   1602 N N     . VAL   A 1 353  ? 154.162 100.504 93.385  1.00 13.28  ? 353  VAL   C N     1 
ATOM   1603 C CA    . VAL   A 1 353  ? 154.781 100.727 92.083  1.00 11.63  ? 353  VAL   C CA    1 
ATOM   1604 C C     . VAL   A 1 353  ? 153.942 101.621 91.180  1.00 16.45  ? 353  VAL   C C     1 
ATOM   1605 O O     . VAL   A 1 353  ? 154.477 102.357 90.350  1.00 24.16  ? 353  VAL   C O     1 
ATOM   1606 C CB    . VAL   A 1 353  ? 155.053 99.380  91.379  1.00 10.89  ? 353  VAL   C CB    1 
ATOM   1607 C CG1   . VAL   A 1 353  ? 153.753 98.704  90.942  1.00 14.00  ? 353  VAL   C CG1   1 
ATOM   1608 C CG2   . VAL   A 1 353  ? 155.937 99.622  90.173  1.00 17.61  ? 353  VAL   C CG2   1 
ATOM   1609 N N     . ALA   A 1 354  ? 152.626 101.554 91.329  1.00 14.81  ? 354  ALA   C N     1 
ATOM   1610 C CA    . ALA   A 1 354  ? 151.732 102.264 90.438  1.00 13.71  ? 354  ALA   C CA    1 
ATOM   1611 C C     . ALA   A 1 354  ? 151.583 103.717 90.836  1.00 16.22  ? 354  ALA   C C     1 
ATOM   1612 O O     . ALA   A 1 354  ? 150.902 104.479 90.151  1.00 21.19  ? 354  ALA   C O     1 
ATOM   1613 C CB    . ALA   A 1 354  ? 150.378 101.593 90.415  1.00 13.57  ? 354  ALA   C CB    1 
ATOM   1614 N N     . LEU   A 1 355  ? 152.233 104.119 91.924  1.00 16.48  ? 355  LEU   C N     1 
ATOM   1615 C CA    . LEU   A 1 355  ? 152.153 105.505 92.346  1.00 18.50  ? 355  LEU   C CA    1 
ATOM   1616 C C     . LEU   A 1 355  ? 152.831 106.400 91.323  1.00 23.28  ? 355  LEU   C C     1 
ATOM   1617 O O     . LEU   A 1 355  ? 152.553 107.597 91.246  1.00 26.95  ? 355  LEU   C O     1 
ATOM   1618 C CB    . LEU   A 1 355  ? 152.794 105.706 93.721  1.00 14.34  ? 355  LEU   C CB    1 
ATOM   1619 C CG    . LEU   A 1 355  ? 152.051 105.096 94.917  1.00 14.32  ? 355  LEU   C CG    1 
ATOM   1620 C CD1   . LEU   A 1 355  ? 152.912 105.229 96.152  1.00 16.12  ? 355  LEU   C CD1   1 
ATOM   1621 C CD2   . LEU   A 1 355  ? 150.725 105.813 95.121  1.00 15.03  ? 355  LEU   C CD2   1 
ATOM   1622 N N     . GLU   A 1 356  ? 153.702 105.819 90.509  1.00 22.04  ? 356  GLU   C N     1 
ATOM   1623 C CA    . GLU   A 1 356  ? 154.418 106.591 89.511  1.00 25.27  ? 356  GLU   C CA    1 
ATOM   1624 C C     . GLU   A 1 356  ? 153.467 107.405 88.636  1.00 27.46  ? 356  GLU   C C     1 
ATOM   1625 O O     . GLU   A 1 356  ? 153.778 108.539 88.269  1.00 31.44  ? 356  GLU   C O     1 
ATOM   1626 C CB    . GLU   A 1 356  ? 155.260 105.664 88.631  1.00 28.03  ? 356  GLU   C CB    1 
ATOM   1627 C CG    . GLU   A 1 356  ? 156.101 106.381 87.584  1.00 35.55  ? 356  GLU   C CG    1 
ATOM   1628 C CD    . GLU   A 1 356  ? 157.185 107.235 88.183  1.00 42.53  ? 356  GLU   C CD    1 
ATOM   1629 O OE1   . GLU   A 1 356  ? 157.526 107.019 89.322  1.00 42.39  ? 356  GLU   C OE1   1 
ATOM   1630 O OE2   . GLU   A 1 356  ? 157.675 108.104 87.502  1.00 42.90  ? 356  GLU   C OE2   1 
ATOM   1631 N N     . LYS   A 1 357  ? 152.310 106.834 88.294  1.00 24.16  ? 357  LYS   C N     1 
ATOM   1632 C CA    . LYS   A 1 357  ? 151.368 107.514 87.413  1.00 21.29  ? 357  LYS   C CA    1 
ATOM   1633 C C     . LYS   A 1 357  ? 150.140 108.036 88.150  1.00 23.37  ? 357  LYS   C C     1 
ATOM   1634 O O     . LYS   A 1 357  ? 149.179 108.477 87.523  1.00 28.77  ? 357  LYS   C O     1 
ATOM   1635 C CB    . LYS   A 1 357  ? 150.940 106.589 86.278  1.00 20.87  ? 357  LYS   C CB    1 
ATOM   1636 C CG    . LYS   A 1 357  ? 152.070 106.224 85.323  1.00 26.47  ? 357  LYS   C CG    1 
ATOM   1637 C CD    . LYS   A 1 357  ? 151.583 105.339 84.186  1.00 30.04  ? 357  LYS   C CD    1 
ATOM   1638 C CE    . LYS   A 1 357  ? 150.906 106.142 83.077  1.00 30.02  ? 357  LYS   C CE    1 
ATOM   1639 N NZ    . LYS   A 1 357  ? 151.892 106.944 82.284  1.00 39.90  ? 357  LYS   C NZ    1 
ATOM   1640 N N     . LEU   A 1 358  ? 150.161 107.963 89.477  1.00 22.12  ? 358  LEU   C N     1 
ATOM   1641 C CA    . LEU   A 1 358  ? 149.039 108.427 90.289  1.00 21.81  ? 358  LEU   C CA    1 
ATOM   1642 C C     . LEU   A 1 358  ? 149.406 109.716 91.026  1.00 26.56  ? 358  LEU   C C     1 
ATOM   1643 O O     . LEU   A 1 358  ? 148.548 110.554 91.310  1.00 29.07  ? 358  LEU   C O     1 
ATOM   1644 C CB    . LEU   A 1 358  ? 148.607 107.332 91.277  1.00 19.51  ? 358  LEU   C CB    1 
ATOM   1645 C CG    . LEU   A 1 358  ? 147.391 107.644 92.169  1.00 16.98  ? 358  LEU   C CG    1 
ATOM   1646 C CD1   . LEU   A 1 358  ? 146.159 107.918 91.321  1.00 23.81  ? 358  LEU   C CD1   1 
ATOM   1647 C CD2   . LEU   A 1 358  ? 147.136 106.469 93.100  1.00 18.01  ? 358  LEU   C CD2   1 
ATOM   1648 N N     . GLN   A 1 359  ? 150.694 109.878 91.323  1.00 26.22  ? 359  GLN   C N     1 
ATOM   1649 C CA    . GLN   A 1 359  ? 151.190 111.032 92.074  1.00 26.58  ? 359  GLN   C CA    1 
ATOM   1650 C C     . GLN   A 1 359  ? 150.868 112.355 91.387  1.00 29.83  ? 359  GLN   C C     1 
ATOM   1651 O O     . GLN   A 1 359  ? 150.832 113.404 92.029  1.00 33.68  ? 359  GLN   C O     1 
ATOM   1652 C CB    . GLN   A 1 359  ? 152.708 110.931 92.255  1.00 28.20  ? 359  GLN   C CB    1 
ATOM   1653 C CG    . GLN   A 1 359  ? 153.500 111.113 90.959  1.00 32.77  ? 359  GLN   C CG    1 
ATOM   1654 C CD    . GLN   A 1 359  ? 154.986 110.890 91.132  1.00 36.43  ? 359  GLN   C CD    1 
ATOM   1655 O OE1   . GLN   A 1 359  ? 155.612 111.443 92.042  1.00 37.50  ? 359  GLN   C OE1   1 
ATOM   1656 N NE2   . GLN   A 1 359  ? 155.564 110.079 90.252  1.00 34.78  ? 359  GLN   C NE2   1 
ATOM   1657 N N     . HIS   A 1 360  ? 150.634 112.302 90.081  1.00 29.60  ? 360  HIS   C N     1 
ATOM   1658 C CA    . HIS   A 1 360  ? 150.370 113.494 89.288  1.00 30.50  ? 360  HIS   C CA    1 
ATOM   1659 C C     . HIS   A 1 360  ? 148.898 113.881 89.323  1.00 31.80  ? 360  HIS   C C     1 
ATOM   1660 O O     . HIS   A 1 360  ? 148.515 114.942 88.832  1.00 35.47  ? 360  HIS   C O     1 
ATOM   1661 C CB    . HIS   A 1 360  ? 150.788 113.260 87.834  1.00 31.00  ? 360  HIS   C CB    1 
ATOM   1662 C CG    . HIS   A 1 360  ? 152.240 112.983 87.676  1.00 34.62  ? 360  HIS   C CG    1 
ATOM   1663 N ND1   . HIS   A 1 360  ? 153.209 113.922 87.946  1.00 38.41  ? 360  HIS   C ND1   1 
ATOM   1664 C CD2   . HIS   A 1 360  ? 152.894 111.869 87.278  1.00 35.37  ? 360  HIS   C CD2   1 
ATOM   1665 C CE1   . HIS   A 1 360  ? 154.399 113.397 87.724  1.00 40.44  ? 360  HIS   C CE1   1 
ATOM   1666 N NE2   . HIS   A 1 360  ? 154.235 112.153 87.317  1.00 36.65  ? 360  HIS   C NE2   1 
ATOM   1667 N N     . LEU   A 1 361  ? 148.067 113.001 89.867  1.00 28.64  ? 361  LEU   C N     1 
ATOM   1668 C CA    . LEU   A 1 361  ? 146.634 113.238 89.902  1.00 26.88  ? 361  LEU   C CA    1 
ATOM   1669 C C     . LEU   A 1 361  ? 146.147 113.594 91.304  1.00 29.00  ? 361  LEU   C C     1 
ATOM   1670 O O     . LEU   A 1 361  ? 145.183 114.339 91.465  1.00 31.85  ? 361  LEU   C O     1 
ATOM   1671 C CB    . LEU   A 1 361  ? 145.902 111.982 89.421  1.00 23.47  ? 361  LEU   C CB    1 
ATOM   1672 C CG    . LEU   A 1 361  ? 146.252 111.484 88.012  1.00 23.58  ? 361  LEU   C CG    1 
ATOM   1673 C CD1   . LEU   A 1 361  ? 145.530 110.178 87.758  1.00 25.77  ? 361  LEU   C CD1   1 
ATOM   1674 C CD2   . LEU   A 1 361  ? 145.843 112.521 86.989  1.00 31.43  ? 361  LEU   C CD2   1 
ATOM   1675 N N     . LEU   A 1 362  ? 146.805 113.030 92.314  1.00 28.10  ? 362  LEU   C N     1 
ATOM   1676 C CA    . LEU   A 1 362  ? 146.355 113.150 93.698  1.00 28.27  ? 362  LEU   C CA    1 
ATOM   1677 C C     . LEU   A 1 362  ? 146.508 114.543 94.305  1.00 31.92  ? 362  LEU   C C     1 
ATOM   1678 O O     . LEU   A 1 362  ? 145.665 114.973 95.094  1.00 30.70  ? 362  LEU   C O     1 
ATOM   1679 C CB    . LEU   A 1 362  ? 147.143 112.176 94.567  1.00 26.67  ? 362  LEU   C CB    1 
ATOM   1680 C CG    . LEU   A 1 362  ? 146.929 110.695 94.290  1.00 23.53  ? 362  LEU   C CG    1 
ATOM   1681 C CD1   . LEU   A 1 362  ? 147.986 109.895 95.045  1.00 24.01  ? 362  LEU   C CD1   1 
ATOM   1682 C CD2   . LEU   A 1 362  ? 145.544 110.276 94.721  1.00 20.21  ? 362  LEU   C CD2   1 
ATOM   1683 N N     . ASP   A 1 363  ? 147.603 115.223 93.976  1.00 35.99  ? 363  ASP   C N     1 
ATOM   1684 C CA    . ASP   A 1 363  ? 147.930 116.547 94.521  1.00 42.06  ? 363  ASP   C CA    1 
ATOM   1685 C C     . ASP   A 1 363  ? 148.185 116.556 96.034  1.00 40.61  ? 363  ASP   C C     1 
ATOM   1686 O O     . ASP   A 1 363  ? 149.306 116.807 96.476  1.00 40.24  ? 363  ASP   C O     1 
ATOM   1687 C CB    . ASP   A 1 363  ? 146.843 117.572 94.184  1.00 45.11  ? 363  ASP   C CB    1 
ATOM   1688 C CG    . ASP   A 1 363  ? 146.827 117.970 92.717  1.00 47.36  ? 363  ASP   C CG    1 
ATOM   1689 O OD1   . ASP   A 1 363  ? 147.801 117.736 92.038  1.00 42.77  ? 363  ASP   C OD1   1 
ATOM   1690 O OD2   . ASP   A 1 363  ? 145.841 118.517 92.292  1.00 49.95  ? 363  ASP   C OD2   1 
ATOM   1691 N N     . HIS   A 1 364  ? 147.144 116.305 96.829  1.00 37.27  ? 364  HIS   C N     1 
ATOM   1692 C CA    . HIS   A 1 364  ? 147.276 116.357 98.288  1.00 35.83  ? 364  HIS   C CA    1 
ATOM   1693 C C     . HIS   A 1 364  ? 146.575 115.204 99.020  1.00 30.46  ? 364  HIS   C C     1 
ATOM   1694 O O     . HIS   A 1 364  ? 145.638 115.445 99.780  1.00 26.85  ? 364  HIS   C O     1 
ATOM   1695 C CB    . HIS   A 1 364  ? 146.707 117.677 98.817  1.00 43.12  ? 364  HIS   C CB    1 
ATOM   1696 C CG    . HIS   A 1 364  ? 147.355 118.889 98.227  1.00 49.41  ? 364  HIS   C CG    1 
ATOM   1697 N ND1   . HIS   A 1 364  ? 148.631 119.289 98.561  1.00 54.49  ? 364  HIS   C ND1   1 
ATOM   1698 C CD2   . HIS   A 1 364  ? 146.900 119.791 97.326  1.00 55.17  ? 364  HIS   C CD2   1 
ATOM   1699 C CE1   . HIS   A 1 364  ? 148.934 120.384 97.885  1.00 58.67  ? 364  HIS   C CE1   1 
ATOM   1700 N NE2   . HIS   A 1 364  ? 147.901 120.707 97.130  1.00 57.64  ? 364  HIS   C NE2   1 
ATOM   1701 N N     . PRO   A 1 365  ? 147.013 113.959 98.806  1.00 21.56  ? 365  PRO   C N     1 
ATOM   1702 C CA    . PRO   A 1 365  ? 146.488 112.735 99.386  1.00 14.92  ? 365  PRO   C CA    1 
ATOM   1703 C C     . PRO   A 1 365  ? 146.975 112.508 100.806 1.00 14.15  ? 365  PRO   C C     1 
ATOM   1704 O O     . PRO   A 1 365  ? 148.071 112.929 101.166 1.00 20.11  ? 365  PRO   C O     1 
ATOM   1705 C CB    . PRO   A 1 365  ? 147.086 111.679 98.466  1.00 16.28  ? 365  PRO   C CB    1 
ATOM   1706 C CG    . PRO   A 1 365  ? 148.412 112.280 98.056  1.00 20.22  ? 365  PRO   C CG    1 
ATOM   1707 C CD    . PRO   A 1 365  ? 148.143 113.748 97.901  1.00 25.87  ? 365  PRO   C CD    1 
ATOM   1708 N N     . ARG   A 1 366  ? 146.214 111.724 101.560 1.00 12.45  ? 366  ARG   C N     1 
ATOM   1709 C CA    . ARG   A 1 366  ? 146.707 111.155 102.808 1.00 9.76   ? 366  ARG   C CA    1 
ATOM   1710 C C     . ARG   A 1 366  ? 147.120 109.703 102.573 1.00 9.09   ? 366  ARG   C C     1 
ATOM   1711 O O     . ARG   A 1 366  ? 146.284 108.868 102.238 1.00 12.33  ? 366  ARG   C O     1 
ATOM   1712 C CB    . ARG   A 1 366  ? 145.640 111.213 103.882 1.00 12.74  ? 366  ARG   C CB    1 
ATOM   1713 C CG    . ARG   A 1 366  ? 146.051 110.632 105.210 1.00 16.67  ? 366  ARG   C CG    1 
ATOM   1714 C CD    . ARG   A 1 366  ? 144.964 110.718 106.197 1.00 17.89  ? 366  ARG   C CD    1 
ATOM   1715 N NE    . ARG   A 1 366  ? 145.351 110.126 107.464 1.00 24.05  ? 366  ARG   C NE    1 
ATOM   1716 C CZ    . ARG   A 1 366  ? 144.555 110.040 108.549 1.00 34.92  ? 366  ARG   C CZ    1 
ATOM   1717 N NH1   . ARG   A 1 366  ? 143.333 110.507 108.505 1.00 34.02  ? 366  ARG   C NH1   1 
ATOM   1718 N NH2   . ARG   A 1 366  ? 145.005 109.481 109.656 1.00 36.83  ? 366  ARG   C NH2   1 
ATOM   1719 N N     . HIS   A 1 367  ? 148.407 109.406 102.721 1.00 7.46   ? 367  HIS   C N     1 
ATOM   1720 C CA    . HIS   A 1 367  ? 148.899 108.062 102.420 1.00 6.07   ? 367  HIS   C CA    1 
ATOM   1721 C C     . HIS   A 1 367  ? 148.902 107.143 103.632 1.00 7.58   ? 367  HIS   C C     1 
ATOM   1722 O O     . HIS   A 1 367  ? 149.400 107.502 104.700 1.00 14.12  ? 367  HIS   C O     1 
ATOM   1723 C CB    . HIS   A 1 367  ? 150.312 108.118 101.835 1.00 7.98   ? 367  HIS   C CB    1 
ATOM   1724 C CG    . HIS   A 1 367  ? 150.380 108.618 100.428 1.00 7.77   ? 367  HIS   C CG    1 
ATOM   1725 N ND1   . HIS   A 1 367  ? 149.986 107.852 99.351  1.00 8.59   ? 367  HIS   C ND1   1 
ATOM   1726 C CD2   . HIS   A 1 367  ? 150.812 109.791 99.918  1.00 8.81   ? 367  HIS   C CD2   1 
ATOM   1727 C CE1   . HIS   A 1 367  ? 150.168 108.540 98.238  1.00 9.91   ? 367  HIS   C CE1   1 
ATOM   1728 N NE2   . HIS   A 1 367  ? 150.675 109.716 98.554  1.00 10.80  ? 367  HIS   C NE2   1 
ATOM   1729 N N     . VAL   A 1 368  ? 148.346 105.948 103.443 1.00 5.40   ? 368  VAL   C N     1 
ATOM   1730 C CA    . VAL   A 1 368  ? 148.295 104.918 104.473 1.00 5.31   ? 368  VAL   C CA    1 
ATOM   1731 C C     . VAL   A 1 368  ? 148.806 103.580 103.942 1.00 5.63   ? 368  VAL   C C     1 
ATOM   1732 O O     . VAL   A 1 368  ? 148.389 103.135 102.875 1.00 0.11   ? 368  VAL   C O     1 
ATOM   1733 C CB    . VAL   A 1 368  ? 146.853 104.749 104.962 1.00 5.79   ? 368  VAL   C CB    1 
ATOM   1734 C CG1   . VAL   A 1 368  ? 146.779 103.659 106.004 1.00 10.54  ? 368  VAL   C CG1   1 
ATOM   1735 C CG2   . VAL   A 1 368  ? 146.342 106.074 105.517 1.00 7.74   ? 368  VAL   C CG2   1 
ATOM   1736 N N     . GLU   A 1 369  ? 149.705 102.937 104.681 1.00 8.10   ? 369  GLU   C N     1 
ATOM   1737 C CA    . GLU   A 1 369  ? 150.220 101.636 104.262 1.00 7.67   ? 369  GLU   C CA    1 
ATOM   1738 C C     . GLU   A 1 369  ? 149.495 100.501 104.974 1.00 9.01   ? 369  GLU   C C     1 
ATOM   1739 O O     . GLU   A 1 369  ? 149.230 100.578 106.174 1.00 13.77  ? 369  GLU   C O     1 
ATOM   1740 C CB    . GLU   A 1 369  ? 151.721 101.538 104.522 1.00 9.63   ? 369  GLU   C CB    1 
ATOM   1741 C CG    . GLU   A 1 369  ? 152.358 100.264 103.988 1.00 12.10  ? 369  GLU   C CG    1 
ATOM   1742 C CD    . GLU   A 1 369  ? 153.842 100.236 104.164 1.00 24.92  ? 369  GLU   C CD    1 
ATOM   1743 O OE1   . GLU   A 1 369  ? 154.365 101.136 104.776 1.00 22.77  ? 369  GLU   C OE1   1 
ATOM   1744 O OE2   . GLU   A 1 369  ? 154.461 99.318  103.681 1.00 28.81  ? 369  GLU   C OE2   1 
ATOM   1745 N N     . ILE   A 1 370  ? 149.180 99.442  104.233 1.00 9.12   ? 370  ILE   C N     1 
ATOM   1746 C CA    . ILE   A 1 370  ? 148.509 98.284  104.815 1.00 8.84   ? 370  ILE   C CA    1 
ATOM   1747 C C     . ILE   A 1 370  ? 149.497 97.166  105.118 1.00 11.41  ? 370  ILE   C C     1 
ATOM   1748 O O     . ILE   A 1 370  ? 150.260 96.742  104.254 1.00 15.00  ? 370  ILE   C O     1 
ATOM   1749 C CB    . ILE   A 1 370  ? 147.399 97.754  103.895 1.00 7.83   ? 370  ILE   C CB    1 
ATOM   1750 C CG1   . ILE   A 1 370  ? 146.355 98.835  103.688 1.00 8.62   ? 370  ILE   C CG1   1 
ATOM   1751 C CG2   . ILE   A 1 370  ? 146.758 96.522  104.526 1.00 9.80   ? 370  ILE   C CG2   1 
ATOM   1752 C CD1   . ILE   A 1 370  ? 145.367 98.532  102.609 1.00 9.83   ? 370  ILE   C CD1   1 
ATOM   1753 N N     . LEU   A 1 371  ? 149.478 96.701  106.362 1.00 11.68  ? 371  LEU   C N     1 
ATOM   1754 C CA    . LEU   A 1 371  ? 150.397 95.673  106.839 1.00 9.46   ? 371  LEU   C CA    1 
ATOM   1755 C C     . LEU   A 1 371  ? 149.767 94.286  106.801 1.00 10.18  ? 371  LEU   C C     1 
ATOM   1756 O O     . LEU   A 1 371  ? 148.549 94.154  106.712 1.00 13.99  ? 371  LEU   C O     1 
ATOM   1757 C CB    . LEU   A 1 371  ? 150.835 95.999  108.268 1.00 10.56  ? 371  LEU   C CB    1 
ATOM   1758 C CG    . LEU   A 1 371  ? 151.996 97.009  108.435 1.00 11.90  ? 371  LEU   C CG    1 
ATOM   1759 C CD1   . LEU   A 1 371  ? 151.666 98.320  107.723 1.00 14.53  ? 371  LEU   C CD1   1 
ATOM   1760 C CD2   . LEU   A 1 371  ? 152.210 97.256  109.921 1.00 16.19  ? 371  LEU   C CD2   1 
ATOM   1761 N N     . GLY   A 1 372  ? 150.607 93.257  106.861 1.00 9.20   ? 372  GLY   C N     1 
ATOM   1762 C CA    . GLY   A 1 372  ? 150.152 91.868  106.825 1.00 9.56   ? 372  GLY   C CA    1 
ATOM   1763 C C     . GLY   A 1 372  ? 149.914 91.301  108.222 1.00 12.47  ? 372  GLY   C C     1 
ATOM   1764 O O     . GLY   A 1 372  ? 149.620 92.036  109.165 1.00 15.18  ? 372  GLY   C O     1 
ATOM   1765 N N     . PHE   A 1 373  ? 150.000 89.980  108.343 1.00 12.73  ? 373  PHE   C N     1 
ATOM   1766 C CA    . PHE   A 1 373  ? 149.685 89.313  109.598 1.00 12.22  ? 373  PHE   C CA    1 
ATOM   1767 C C     . PHE   A 1 373  ? 150.874 89.246  110.548 1.00 17.60  ? 373  PHE   C C     1 
ATOM   1768 O O     . PHE   A 1 373  ? 151.991 88.914  110.146 1.00 19.71  ? 373  PHE   C O     1 
ATOM   1769 C CB    . PHE   A 1 373  ? 149.208 87.879  109.334 1.00 13.45  ? 373  PHE   C CB    1 
ATOM   1770 C CG    . PHE   A 1 373  ? 147.841 87.710  108.673 1.00 11.11  ? 373  PHE   C CG    1 
ATOM   1771 C CD1   . PHE   A 1 373  ? 146.896 88.724  108.644 1.00 13.26  ? 373  PHE   C CD1   1 
ATOM   1772 C CD2   . PHE   A 1 373  ? 147.507 86.495  108.084 1.00 10.47  ? 373  PHE   C CD2   1 
ATOM   1773 C CE1   . PHE   A 1 373  ? 145.670 88.523  108.047 1.00 13.93  ? 373  PHE   C CE1   1 
ATOM   1774 C CE2   . PHE   A 1 373  ? 146.281 86.304  107.491 1.00 9.44   ? 373  PHE   C CE2   1 
ATOM   1775 C CZ    . PHE   A 1 373  ? 145.365 87.318  107.474 1.00 12.88  ? 373  PHE   C CZ    1 
ATOM   1776 N N     . SER   A 1 374  ? 150.606 89.494  111.826 1.00 20.52  ? 374  SER   C N     1 
ATOM   1777 C CA    . SER   A 1 374  ? 151.580 89.292  112.891 1.00 21.78  ? 374  SER   C CA    1 
ATOM   1778 C C     . SER   A 1 374  ? 151.547 87.830  113.304 1.00 24.93  ? 374  SER   C C     1 
ATOM   1779 O O     . SER   A 1 374  ? 150.637 87.098  112.915 1.00 26.50  ? 374  SER   C O     1 
ATOM   1780 C CB    . SER   A 1 374  ? 151.262 90.177  114.077 1.00 25.59  ? 374  SER   C CB    1 
ATOM   1781 O OG    . SER   A 1 374  ? 150.051 89.797  114.677 1.00 29.14  ? 374  SER   C OG    1 
ATOM   1782 N N     . GLU   A 1 375  ? 152.511 87.391  114.100 1.00 24.36  ? 375  GLU   C N     1 
ATOM   1783 C CA    . GLU   A 1 375  ? 152.566 85.979  114.462 1.00 24.45  ? 375  GLU   C CA    1 
ATOM   1784 C C     . GLU   A 1 375  ? 151.271 85.503  115.118 1.00 26.23  ? 375  GLU   C C     1 
ATOM   1785 O O     . GLU   A 1 375  ? 150.797 84.398  114.847 1.00 29.44  ? 375  GLU   C O     1 
ATOM   1786 C CB    . GLU   A 1 375  ? 153.750 85.726  115.393 1.00 25.29  ? 375  GLU   C CB    1 
ATOM   1787 C CG    . GLU   A 1 375  ? 155.113 85.933  114.739 1.00 28.05  ? 375  GLU   C CG    1 
ATOM   1788 C CD    . GLU   A 1 375  ? 155.522 87.381  114.677 1.00 34.03  ? 375  GLU   C CD    1 
ATOM   1789 O OE1   . GLU   A 1 375  ? 154.779 88.209  115.155 1.00 31.36  ? 375  GLU   C OE1   1 
ATOM   1790 O OE2   . GLU   A 1 375  ? 156.570 87.660  114.147 1.00 33.79  ? 375  GLU   C OE2   1 
ATOM   1791 N N     . ALA   A 1 376  ? 150.688 86.348  115.962 1.00 25.81  ? 376  ALA   C N     1 
ATOM   1792 C CA    . ALA   A 1 376  ? 149.445 85.999  116.640 1.00 27.86  ? 376  ALA   C CA    1 
ATOM   1793 C C     . ALA   A 1 376  ? 148.302 85.827  115.647 1.00 29.89  ? 376  ALA   C C     1 
ATOM   1794 O O     . ALA   A 1 376  ? 147.443 84.958  115.821 1.00 33.83  ? 376  ALA   C O     1 
ATOM   1795 C CB    . ALA   A 1 376  ? 149.087 87.074  117.652 1.00 32.49  ? 376  ALA   C CB    1 
ATOM   1796 N N     . LYS   A 1 377  ? 148.280 86.670  114.622 1.00 26.10  ? 377  LYS   C N     1 
ATOM   1797 C CA    . LYS   A 1 377  ? 147.217 86.648  113.628 1.00 23.33  ? 377  LYS   C CA    1 
ATOM   1798 C C     . LYS   A 1 377  ? 147.374 85.473  112.677 1.00 23.32  ? 377  LYS   C C     1 
ATOM   1799 O O     . LYS   A 1 377  ? 146.388 84.879  112.243 1.00 25.48  ? 377  LYS   C O     1 
ATOM   1800 C CB    . LYS   A 1 377  ? 147.183 87.968  112.867 1.00 22.37  ? 377  LYS   C CB    1 
ATOM   1801 C CG    . LYS   A 1 377  ? 146.649 89.141  113.688 1.00 25.56  ? 377  LYS   C CG    1 
ATOM   1802 C CD    . LYS   A 1 377  ? 146.658 90.443  112.886 1.00 28.19  ? 377  LYS   C CD    1 
ATOM   1803 C CE    . LYS   A 1 377  ? 145.888 91.558  113.602 1.00 38.32  ? 377  LYS   C CE    1 
ATOM   1804 N NZ    . LYS   A 1 377  ? 146.481 91.897  114.926 1.00 41.02  ? 377  LYS   C NZ    1 
ATOM   1805 N N     . ARG   A 1 378  ? 148.620 85.128  112.365 1.00 23.18  ? 378  ARG   C N     1 
ATOM   1806 C CA    . ARG   A 1 378  ? 148.875 84.011  111.469 1.00 22.21  ? 378  ARG   C CA    1 
ATOM   1807 C C     . ARG   A 1 378  ? 148.330 82.745  112.101 1.00 29.82  ? 378  ARG   C C     1 
ATOM   1808 O O     . ARG   A 1 378  ? 147.678 81.940  111.437 1.00 32.84  ? 378  ARG   C O     1 
ATOM   1809 C CB    . ARG   A 1 378  ? 150.369 83.844  111.224 1.00 21.21  ? 378  ARG   C CB    1 
ATOM   1810 C CG    . ARG   A 1 378  ? 151.011 84.986  110.471 1.00 20.97  ? 378  ARG   C CG    1 
ATOM   1811 C CD    . ARG   A 1 378  ? 152.475 84.896  110.466 1.00 19.11  ? 378  ARG   C CD    1 
ATOM   1812 N NE    . ARG   A 1 378  ? 153.069 86.205  110.292 1.00 17.49  ? 378  ARG   C NE    1 
ATOM   1813 C CZ    . ARG   A 1 378  ? 154.381 86.476  110.359 1.00 19.16  ? 378  ARG   C CZ    1 
ATOM   1814 N NH1   . ARG   A 1 378  ? 155.253 85.518  110.567 1.00 21.81  ? 378  ARG   C NH1   1 
ATOM   1815 N NH2   . ARG   A 1 378  ? 154.781 87.722  110.219 1.00 19.90  ? 378  ARG   C NH2   1 
ATOM   1816 N N     . LYS   A 1 379  ? 148.569 82.588  113.401 1.00 31.98  ? 379  LYS   C N     1 
ATOM   1817 C CA    . LYS   A 1 379  ? 148.087 81.418  114.113 1.00 33.05  ? 379  LYS   C CA    1 
ATOM   1818 C C     . LYS   A 1 379  ? 146.569 81.336  114.076 1.00 34.14  ? 379  LYS   C C     1 
ATOM   1819 O O     . LYS   A 1 379  ? 146.016 80.276  113.776 1.00 35.98  ? 379  LYS   C O     1 
ATOM   1820 C CB    . LYS   A 1 379  ? 148.582 81.420  115.557 1.00 34.33  ? 379  LYS   C CB    1 
ATOM   1821 C CG    . LYS   A 1 379  ? 148.192 80.181  116.351 1.00 39.42  ? 379  LYS   C CG    1 
ATOM   1822 C CD    . LYS   A 1 379  ? 148.797 80.209  117.741 1.00 42.58  ? 379  LYS   C CD    1 
ATOM   1823 C CE    . LYS   A 1 379  ? 148.400 78.987  118.544 1.00 43.45  ? 379  LYS   C CE    1 
ATOM   1824 N NZ    . LYS   A 1 379  ? 148.971 79.021  119.919 1.00 48.07  ? 379  LYS   C NZ    1 
ATOM   1825 N N     . GLU   A 1 380  ? 145.888 82.453  114.339 1.00 32.88  ? 380  GLU   C N     1 
ATOM   1826 C CA    . GLU   A 1 380  ? 144.433 82.419  114.325 1.00 34.73  ? 380  GLU   C CA    1 
ATOM   1827 C C     . GLU   A 1 380  ? 143.908 82.016  112.961 1.00 37.45  ? 380  GLU   C C     1 
ATOM   1828 O O     . GLU   A 1 380  ? 142.977 81.217  112.868 1.00 40.09  ? 380  GLU   C O     1 
ATOM   1829 C CB    . GLU   A 1 380  ? 143.826 83.771  114.702 1.00 34.51  ? 380  GLU   C CB    1 
ATOM   1830 C CG    . GLU   A 1 380  ? 143.935 84.148  116.170 1.00 37.65  ? 380  GLU   C CG    1 
ATOM   1831 C CD    . GLU   A 1 380  ? 143.165 85.408  116.498 1.00 47.62  ? 380  GLU   C CD    1 
ATOM   1832 O OE1   . GLU   A 1 380  ? 142.647 86.016  115.586 1.00 44.20  ? 380  GLU   C OE1   1 
ATOM   1833 O OE2   . GLU   A 1 380  ? 143.091 85.758  117.651 1.00 52.41  ? 380  GLU   C OE2   1 
ATOM   1834 N N     . TYR   A 1 381  ? 144.526 82.523  111.898 1.00 32.14  ? 381  TYR   C N     1 
ATOM   1835 C CA    . TYR   A 1 381  ? 144.064 82.198  110.558 1.00 28.51  ? 381  TYR   C CA    1 
ATOM   1836 C C     . TYR   A 1 381  ? 143.980 80.692  110.373 1.00 31.67  ? 381  TYR   C C     1 
ATOM   1837 O O     . TYR   A 1 381  ? 142.992 80.182  109.845 1.00 37.64  ? 381  TYR   C O     1 
ATOM   1838 C CB    . TYR   A 1 381  ? 144.978 82.789  109.488 1.00 23.98  ? 381  TYR   C CB    1 
ATOM   1839 C CG    . TYR   A 1 381  ? 144.455 82.575  108.083 1.00 22.79  ? 381  TYR   C CG    1 
ATOM   1840 C CD1   . TYR   A 1 381  ? 143.631 83.527  107.508 1.00 21.28  ? 381  TYR   C CD1   1 
ATOM   1841 C CD2   . TYR   A 1 381  ? 144.781 81.428  107.376 1.00 26.19  ? 381  TYR   C CD2   1 
ATOM   1842 C CE1   . TYR   A 1 381  ? 143.142 83.340  106.237 1.00 17.17  ? 381  TYR   C CE1   1 
ATOM   1843 C CE2   . TYR   A 1 381  ? 144.283 81.243  106.101 1.00 23.30  ? 381  TYR   C CE2   1 
ATOM   1844 C CZ    . TYR   A 1 381  ? 143.470 82.197  105.534 1.00 18.87  ? 381  TYR   C CZ    1 
ATOM   1845 O OH    . TYR   A 1 381  ? 142.978 82.014  104.266 1.00 20.82  ? 381  TYR   C OH    1 
ATOM   1846 N N     . PHE   A 1 382  ? 145.017 79.977  110.797 1.00 32.92  ? 382  PHE   C N     1 
ATOM   1847 C CA    . PHE   A 1 382  ? 145.046 78.530  110.624 1.00 34.58  ? 382  PHE   C CA    1 
ATOM   1848 C C     . PHE   A 1 382  ? 143.938 77.852  111.422 1.00 40.12  ? 382  PHE   C C     1 
ATOM   1849 O O     . PHE   A 1 382  ? 143.305 76.912  110.937 1.00 42.56  ? 382  PHE   C O     1 
ATOM   1850 C CB    . PHE   A 1 382  ? 146.405 77.968  111.043 1.00 34.87  ? 382  PHE   C CB    1 
ATOM   1851 C CG    . PHE   A 1 382  ? 147.508 78.365  110.116 1.00 32.43  ? 382  PHE   C CG    1 
ATOM   1852 C CD1   . PHE   A 1 382  ? 148.427 79.321  110.489 1.00 31.73  ? 382  PHE   C CD1   1 
ATOM   1853 C CD2   . PHE   A 1 382  ? 147.615 77.805  108.869 1.00 29.25  ? 382  PHE   C CD2   1 
ATOM   1854 C CE1   . PHE   A 1 382  ? 149.431 79.716  109.637 1.00 30.85  ? 382  PHE   C CE1   1 
ATOM   1855 C CE2   . PHE   A 1 382  ? 148.616 78.197  108.012 1.00 25.33  ? 382  PHE   C CE2   1 
ATOM   1856 C CZ    . PHE   A 1 382  ? 149.523 79.158  108.397 1.00 27.32  ? 382  PHE   C CZ    1 
ATOM   1857 N N     . PHE   A 1 383  ? 143.697 78.327  112.638 1.00 40.36  ? 383  PHE   C N     1 
ATOM   1858 C CA    . PHE   A 1 383  ? 142.662 77.737  113.480 1.00 44.36  ? 383  PHE   C CA    1 
ATOM   1859 C C     . PHE   A 1 383  ? 141.255 78.078  113.000 1.00 43.99  ? 383  PHE   C C     1 
ATOM   1860 O O     . PHE   A 1 383  ? 140.332 77.281  113.161 1.00 46.11  ? 383  PHE   C O     1 
ATOM   1861 C CB    . PHE   A 1 383  ? 142.861 78.144  114.938 1.00 43.07  ? 383  PHE   C CB    1 
ATOM   1862 C CG    . PHE   A 1 383  ? 143.897 77.300  115.628 1.00 42.97  ? 383  PHE   C CG    1 
ATOM   1863 C CD1   . PHE   A 1 383  ? 145.225 77.673  115.637 1.00 43.41  ? 383  PHE   C CD1   1 
ATOM   1864 C CD2   . PHE   A 1 383  ? 143.540 76.124  116.261 1.00 49.59  ? 383  PHE   C CD2   1 
ATOM   1865 C CE1   . PHE   A 1 383  ? 146.175 76.897  116.254 1.00 44.82  ? 383  PHE   C CE1   1 
ATOM   1866 C CE2   . PHE   A 1 383  ? 144.489 75.344  116.883 1.00 54.90  ? 383  PHE   C CE2   1 
ATOM   1867 C CZ    . PHE   A 1 383  ? 145.810 75.735  116.876 1.00 49.72  ? 383  PHE   C CZ    1 
ATOM   1868 N N     . LYS   A 1 384  ? 141.090 79.251  112.403 1.00 41.71  ? 384  LYS   C N     1 
ATOM   1869 C CA    . LYS   A 1 384  ? 139.797 79.626  111.849 1.00 44.15  ? 384  LYS   C CA    1 
ATOM   1870 C C     . LYS   A 1 384  ? 139.549 78.890  110.532 1.00 41.14  ? 384  LYS   C C     1 
ATOM   1871 O O     . LYS   A 1 384  ? 138.419 78.496  110.232 1.00 48.13  ? 384  LYS   C O     1 
ATOM   1872 C CB    . LYS   A 1 384  ? 139.714 81.144  111.669 1.00 40.14  ? 384  LYS   C CB    1 
ATOM   1873 C CG    . LYS   A 1 384  ? 139.648 81.905  112.996 1.00 45.48  ? 384  LYS   C CG    1 
ATOM   1874 C CD    . LYS   A 1 384  ? 139.611 83.417  112.809 1.00 46.74  ? 384  LYS   C CD    1 
ATOM   1875 C CE    . LYS   A 1 384  ? 139.579 84.124  114.167 1.00 48.19  ? 384  LYS   C CE    1 
ATOM   1876 N NZ    . LYS   A 1 384  ? 139.604 85.606  114.039 1.00 44.70  ? 384  LYS   C NZ    1 
ATOM   1877 N N     . TYR   A 1 385  ? 140.611 78.702  109.749 1.00 39.74  ? 385  TYR   C N     1 
ATOM   1878 C CA    . TYR   A 1 385  ? 140.534 77.997  108.474 1.00 40.17  ? 385  TYR   C CA    1 
ATOM   1879 C C     . TYR   A 1 385  ? 140.226 76.515  108.676 1.00 44.88  ? 385  TYR   C C     1 
ATOM   1880 O O     . TYR   A 1 385  ? 139.349 75.959  108.011 1.00 46.09  ? 385  TYR   C O     1 
ATOM   1881 C CB    . TYR   A 1 385  ? 141.840 78.156  107.694 1.00 41.81  ? 385  TYR   C CB    1 
ATOM   1882 C CG    . TYR   A 1 385  ? 141.795 77.575  106.304 1.00 36.52  ? 385  TYR   C CG    1 
ATOM   1883 C CD1   . TYR   A 1 385  ? 141.427 78.368  105.234 1.00 33.35  ? 385  TYR   C CD1   1 
ATOM   1884 C CD2   . TYR   A 1 385  ? 142.107 76.249  106.101 1.00 39.60  ? 385  TYR   C CD2   1 
ATOM   1885 C CE1   . TYR   A 1 385  ? 141.385 77.831  103.965 1.00 32.62  ? 385  TYR   C CE1   1 
ATOM   1886 C CE2   . TYR   A 1 385  ? 142.063 75.712  104.839 1.00 38.37  ? 385  TYR   C CE2   1 
ATOM   1887 C CZ    . TYR   A 1 385  ? 141.703 76.496  103.772 1.00 34.52  ? 385  TYR   C CZ    1 
ATOM   1888 O OH    . TYR   A 1 385  ? 141.658 75.960  102.509 1.00 37.11  ? 385  TYR   C OH    1 
ATOM   1889 N N     . PHE   A 1 386  ? 140.955 75.872  109.589 1.00 44.63  ? 386  PHE   C N     1 
ATOM   1890 C CA    . PHE   A 1 386  ? 140.768 74.454  109.864 1.00 46.69  ? 386  PHE   C CA    1 
ATOM   1891 C C     . PHE   A 1 386  ? 139.847 74.260  111.065 1.00 50.70  ? 386  PHE   C C     1 
ATOM   1892 O O     . PHE   A 1 386  ? 140.256 74.450  112.208 1.00 51.64  ? 386  PHE   C O     1 
ATOM   1893 C CB    . PHE   A 1 386  ? 142.115 73.771  110.133 1.00 46.12  ? 386  PHE   C CB    1 
ATOM   1894 C CG    . PHE   A 1 386  ? 143.038 73.680  108.938 1.00 43.81  ? 386  PHE   C CG    1 
ATOM   1895 C CD1   . PHE   A 1 386  ? 144.073 74.592  108.762 1.00 41.70  ? 386  PHE   C CD1   1 
ATOM   1896 C CD2   . PHE   A 1 386  ? 142.874 72.688  107.991 1.00 42.84  ? 386  PHE   C CD2   1 
ATOM   1897 C CE1   . PHE   A 1 386  ? 144.913 74.508  107.670 1.00 40.95  ? 386  PHE   C CE1   1 
ATOM   1898 C CE2   . PHE   A 1 386  ? 143.714 72.606  106.903 1.00 41.71  ? 386  PHE   C CE2   1 
ATOM   1899 C CZ    . PHE   A 1 386  ? 144.731 73.516  106.740 1.00 42.50  ? 386  PHE   C CZ    1 
ATOM   1900 N N     . SER   A 1 387  ? 138.600 73.873  110.798 1.00 53.92  ? 387  SER   C N     1 
ATOM   1901 C CA    . SER   A 1 387  ? 137.577 73.768  111.839 1.00 56.04  ? 387  SER   C CA    1 
ATOM   1902 C C     . SER   A 1 387  ? 137.912 72.726  112.904 1.00 57.78  ? 387  SER   C C     1 
ATOM   1903 O O     . SER   A 1 387  ? 137.489 72.849  114.056 1.00 59.15  ? 387  SER   C O     1 
ATOM   1904 C CB    . SER   A 1 387  ? 136.243 73.429  111.205 1.00 59.86  ? 387  SER   C CB    1 
ATOM   1905 O OG    . SER   A 1 387  ? 136.279 72.158  110.616 1.00 57.19  ? 387  SER   C OG    1 
ATOM   1906 N N     . ASP   A 1 388  ? 138.688 71.717  112.529 1.00 58.36  ? 388  ASP   C N     1 
ATOM   1907 C CA    . ASP   A 1 388  ? 139.138 70.704  113.473 1.00 59.86  ? 388  ASP   C CA    1 
ATOM   1908 C C     . ASP   A 1 388  ? 140.434 71.146  114.127 1.00 60.29  ? 388  ASP   C C     1 
ATOM   1909 O O     . ASP   A 1 388  ? 141.476 71.193  113.472 1.00 75.45  ? 388  ASP   C O     1 
ATOM   1910 C CB    . ASP   A 1 388  ? 139.350 69.354  112.792 1.00 62.34  ? 388  ASP   C CB    1 
ATOM   1911 C CG    . ASP   A 1 388  ? 139.799 68.266  113.783 1.00 61.53  ? 388  ASP   C CG    1 
ATOM   1912 O OD1   . ASP   A 1 388  ? 139.937 68.579  114.953 1.00 61.00  ? 388  ASP   C OD1   1 
ATOM   1913 O OD2   . ASP   A 1 388  ? 140.011 67.147  113.363 1.00 65.71  ? 388  ASP   C OD2   1 
ATOM   1914 N N     . GLU   A 1 389  ? 140.378 71.468  115.414 1.00 59.61  ? 389  GLU   C N     1 
ATOM   1915 C CA    . GLU   A 1 389  ? 141.547 71.987  116.110 1.00 58.96  ? 389  GLU   C CA    1 
ATOM   1916 C C     . GLU   A 1 389  ? 142.714 71.007  116.057 1.00 58.77  ? 389  GLU   C C     1 
ATOM   1917 O O     . GLU   A 1 389  ? 143.874 71.421  116.056 1.00 75.18  ? 389  GLU   C O     1 
ATOM   1918 C CB    . GLU   A 1 389  ? 141.214 72.325  117.562 1.00 64.41  ? 389  GLU   C CB    1 
ATOM   1919 C CG    . GLU   A 1 389  ? 140.312 73.543  117.729 1.00 68.15  ? 389  GLU   C CG    1 
ATOM   1920 C CD    . GLU   A 1 389  ? 140.021 73.862  119.167 1.00 75.72  ? 389  GLU   C CD    1 
ATOM   1921 O OE1   . GLU   A 1 389  ? 140.420 73.101  120.014 1.00 76.32  ? 389  GLU   C OE1   1 
ATOM   1922 O OE2   . GLU   A 1 389  ? 139.397 74.866  119.419 1.00 72.92  ? 389  GLU   C OE2   1 
ATOM   1923 N N     . ALA   A 1 390  ? 142.424 69.707  116.018 1.00 58.27  ? 390  ALA   C N     1 
ATOM   1924 C CA    . ALA   A 1 390  ? 143.492 68.720  115.949 1.00 60.80  ? 390  ALA   C CA    1 
ATOM   1925 C C     . ALA   A 1 390  ? 144.289 68.892  114.660 1.00 62.06  ? 390  ALA   C C     1 
ATOM   1926 O O     . ALA   A 1 390  ? 145.506 68.692  114.633 1.00 58.33  ? 390  ALA   C O     1 
ATOM   1927 C CB    . ALA   A 1 390  ? 142.926 67.313  116.031 1.00 63.59  ? 390  ALA   C CB    1 
ATOM   1928 N N     . GLN   A 1 391  ? 143.595 69.264  113.588 1.00 60.43  ? 391  GLN   C N     1 
ATOM   1929 C CA    . GLN   A 1 391  ? 144.229 69.423  112.291 1.00 54.66  ? 391  GLN   C CA    1 
ATOM   1930 C C     . GLN   A 1 391  ? 144.852 70.801  112.187 1.00 50.05  ? 391  GLN   C C     1 
ATOM   1931 O O     . GLN   A 1 391  ? 145.886 70.974  111.535 1.00 48.89  ? 391  GLN   C O     1 
ATOM   1932 C CB    . GLN   A 1 391  ? 143.205 69.204  111.183 1.00 58.69  ? 391  GLN   C CB    1 
ATOM   1933 C CG    . GLN   A 1 391  ? 142.674 67.777  111.119 1.00 62.03  ? 391  GLN   C CG    1 
ATOM   1934 C CD    . GLN   A 1 391  ? 141.573 67.596  110.085 1.00 65.95  ? 391  GLN   C CD    1 
ATOM   1935 O OE1   . GLN   A 1 391  ? 141.728 67.966  108.919 1.00 67.74  ? 391  GLN   C OE1   1 
ATOM   1936 N NE2   . GLN   A 1 391  ? 140.449 67.027  110.510 1.00 68.95  ? 391  GLN   C NE2   1 
ATOM   1937 N N     . ALA   A 1 392  ? 144.241 71.779  112.847 1.00 49.89  ? 392  ALA   C N     1 
ATOM   1938 C CA    . ALA   A 1 392  ? 144.777 73.123  112.880 1.00 47.85  ? 392  ALA   C CA    1 
ATOM   1939 C C     . ALA   A 1 392  ? 146.136 73.124  113.559 1.00 48.64  ? 392  ALA   C C     1 
ATOM   1940 O O     . ALA   A 1 392  ? 147.060 73.795  113.121 1.00 50.94  ? 392  ALA   C O     1 
ATOM   1941 C CB    . ALA   A 1 392  ? 143.844 74.070  113.593 1.00 47.04  ? 392  ALA   C CB    1 
ATOM   1942 N N     . ARG   A 1 393  ? 146.251 72.329  114.631 1.00 50.60  ? 393  ARG   C N     1 
ATOM   1943 C CA    . ARG   A 1 393  ? 147.527 72.222  115.324 1.00 50.05  ? 393  ARG   C CA    1 
ATOM   1944 C C     . ARG   A 1 393  ? 148.569 71.585  114.425 1.00 49.86  ? 393  ARG   C C     1 
ATOM   1945 O O     . ARG   A 1 393  ? 149.705 72.065  114.358 1.00 48.06  ? 393  ARG   C O     1 
ATOM   1946 C CB    . ARG   A 1 393  ? 147.391 71.402  116.603 1.00 55.79  ? 393  ARG   C CB    1 
ATOM   1947 C CG    . ARG   A 1 393  ? 146.696 72.121  117.748 1.00 58.79  ? 393  ARG   C CG    1 
ATOM   1948 C CD    . ARG   A 1 393  ? 146.869 71.419  119.048 1.00 64.61  ? 393  ARG   C CD    1 
ATOM   1949 N NE    . ARG   A 1 393  ? 146.202 70.121  119.080 1.00 68.35  ? 393  ARG   C NE    1 
ATOM   1950 C CZ    . ARG   A 1 393  ? 144.913 69.918  119.434 1.00 68.02  ? 393  ARG   C CZ    1 
ATOM   1951 N NH1   . ARG   A 1 393  ? 144.147 70.932  119.772 1.00 71.88  ? 393  ARG   C NH1   1 
ATOM   1952 N NH2   . ARG   A 1 393  ? 144.418 68.691  119.445 1.00 72.84  ? 393  ARG   C NH2   1 
ATOM   1953 N N     . ALA   A 1 394  ? 148.198 70.533  113.704 1.00 50.19  ? 394  ALA   C N     1 
ATOM   1954 C CA    . ALA   A 1 394  ? 149.139 69.894  112.804 1.00 50.57  ? 394  ALA   C CA    1 
ATOM   1955 C C     . ALA   A 1 394  ? 149.605 70.870  111.727 1.00 49.39  ? 394  ALA   C C     1 
ATOM   1956 O O     . ALA   A 1 394  ? 150.792 70.976  111.444 1.00 47.83  ? 394  ALA   C O     1 
ATOM   1957 C CB    . ALA   A 1 394  ? 148.518 68.666  112.164 1.00 52.68  ? 394  ALA   C CB    1 
ATOM   1958 N N     . ALA   A 1 395  ? 148.650 71.605  111.144 1.00 47.27  ? 395  ALA   C N     1 
ATOM   1959 C CA    . ALA   A 1 395  ? 148.996 72.541  110.077 1.00 42.05  ? 395  ALA   C CA    1 
ATOM   1960 C C     . ALA   A 1 395  ? 149.901 73.637  110.599 1.00 40.98  ? 395  ALA   C C     1 
ATOM   1961 O O     . ALA   A 1 395  ? 150.902 73.982  109.957 1.00 43.93  ? 395  ALA   C O     1 
ATOM   1962 C CB    . ALA   A 1 395  ? 147.733 73.161  109.497 1.00 42.79  ? 395  ALA   C CB    1 
ATOM   1963 N N     . PHE   A 1 396  ? 149.588 74.163  111.772 1.00 39.79  ? 396  PHE   C N     1 
ATOM   1964 C CA    . PHE   A 1 396  ? 150.376 75.239  112.329 1.00 35.94  ? 396  PHE   C CA    1 
ATOM   1965 C C     . PHE   A 1 396  ? 151.797 74.784  112.605 1.00 39.94  ? 396  PHE   C C     1 
ATOM   1966 O O     . PHE   A 1 396  ? 152.747 75.482  112.257 1.00 41.63  ? 396  PHE   C O     1 
ATOM   1967 C CB    . PHE   A 1 396  ? 149.754 75.791  113.604 1.00 35.57  ? 396  PHE   C CB    1 
ATOM   1968 C CG    . PHE   A 1 396  ? 150.489 76.978  114.101 1.00 35.00  ? 396  PHE   C CG    1 
ATOM   1969 C CD1   . PHE   A 1 396  ? 150.320 78.195  113.482 1.00 34.30  ? 396  PHE   C CD1   1 
ATOM   1970 C CD2   . PHE   A 1 396  ? 151.361 76.889  115.169 1.00 40.75  ? 396  PHE   C CD2   1 
ATOM   1971 C CE1   . PHE   A 1 396  ? 151.005 79.306  113.909 1.00 36.84  ? 396  PHE   C CE1   1 
ATOM   1972 C CE2   . PHE   A 1 396  ? 152.049 78.001  115.603 1.00 42.58  ? 396  PHE   C CE2   1 
ATOM   1973 C CZ    . PHE   A 1 396  ? 151.868 79.211  114.970 1.00 39.85  ? 396  PHE   C CZ    1 
ATOM   1974 N N     . SER   A 1 397  ? 151.950 73.614  113.225 1.00 42.02  ? 397  SER   C N     1 
ATOM   1975 C CA    . SER   A 1 397  ? 153.276 73.107  113.562 1.00 42.73  ? 397  SER   C CA    1 
ATOM   1976 C C     . SER   A 1 397  ? 154.121 72.851  112.320 1.00 44.73  ? 397  SER   C C     1 
ATOM   1977 O O     . SER   A 1 397  ? 155.311 73.164  112.298 1.00 45.01  ? 397  SER   C O     1 
ATOM   1978 C CB    . SER   A 1 397  ? 153.160 71.826  114.366 1.00 46.79  ? 397  SER   C CB    1 
ATOM   1979 O OG    . SER   A 1 397  ? 152.623 72.072  115.638 1.00 50.60  ? 397  SER   C OG    1 
ATOM   1980 N N     . LEU   A 1 398  ? 153.506 72.317  111.270 1.00 43.37  ? 398  LEU   C N     1 
ATOM   1981 C CA    . LEU   A 1 398  ? 154.240 72.029  110.042 1.00 42.44  ? 398  LEU   C CA    1 
ATOM   1982 C C     . LEU   A 1 398  ? 154.833 73.294  109.443 1.00 41.85  ? 398  LEU   C C     1 
ATOM   1983 O O     . LEU   A 1 398  ? 155.944 73.280  108.912 1.00 42.00  ? 398  LEU   C O     1 
ATOM   1984 C CB    . LEU   A 1 398  ? 153.309 71.367  109.019 1.00 43.06  ? 398  LEU   C CB    1 
ATOM   1985 C CG    . LEU   A 1 398  ? 152.876 69.929  109.330 1.00 52.42  ? 398  LEU   C CG    1 
ATOM   1986 C CD1   . LEU   A 1 398  ? 151.713 69.555  108.433 1.00 54.86  ? 398  LEU   C CD1   1 
ATOM   1987 C CD2   . LEU   A 1 398  ? 154.043 68.984  109.096 1.00 58.44  ? 398  LEU   C CD2   1 
ATOM   1988 N N     . ILE   A 1 399  ? 154.100 74.393  109.547 1.00 38.86  ? 399  ILE   C N     1 
ATOM   1989 C CA    . ILE   A 1 399  ? 154.556 75.668  109.018 1.00 33.79  ? 399  ILE   C CA    1 
ATOM   1990 C C     . ILE   A 1 399  ? 155.490 76.374  109.995 1.00 36.66  ? 399  ILE   C C     1 
ATOM   1991 O O     . ILE   A 1 399  ? 156.506 76.931  109.593 1.00 37.93  ? 399  ILE   C O     1 
ATOM   1992 C CB    . ILE   A 1 399  ? 153.361 76.558  108.676 1.00 28.51  ? 399  ILE   C CB    1 
ATOM   1993 C CG1   . ILE   A 1 399  ? 152.563 75.876  107.577 1.00 29.83  ? 399  ILE   C CG1   1 
ATOM   1994 C CG2   . ILE   A 1 399  ? 153.840 77.943  108.224 1.00 31.07  ? 399  ILE   C CG2   1 
ATOM   1995 C CD1   . ILE   A 1 399  ? 151.214 76.448  107.376 1.00 34.31  ? 399  ILE   C CD1   1 
ATOM   1996 N N     . GLN   A 1 400  ? 155.161 76.340  111.282 1.00 39.07  ? 400  GLN   C N     1 
ATOM   1997 C CA    . GLN   A 1 400  ? 155.977 76.998  112.301 1.00 38.51  ? 400  GLN   C CA    1 
ATOM   1998 C C     . GLN   A 1 400  ? 157.416 76.488  112.279 1.00 39.32  ? 400  GLN   C C     1 
ATOM   1999 O O     . GLN   A 1 400  ? 158.354 77.258  112.494 1.00 39.47  ? 400  GLN   C O     1 
ATOM   2000 C CB    . GLN   A 1 400  ? 155.374 76.780  113.693 1.00 39.15  ? 400  GLN   C CB    1 
ATOM   2001 C CG    . GLN   A 1 400  ? 156.128 77.469  114.830 1.00 39.40  ? 400  GLN   C CG    1 
ATOM   2002 C CD    . GLN   A 1 400  ? 156.046 78.987  114.787 1.00 46.00  ? 400  GLN   C CD    1 
ATOM   2003 O OE1   . GLN   A 1 400  ? 155.012 79.575  115.120 1.00 41.96  ? 400  GLN   C OE1   1 
ATOM   2004 N NE2   . GLN   A 1 400  ? 157.133 79.626  114.372 1.00 43.94  ? 400  GLN   C NE2   1 
ATOM   2005 N N     . GLU   A 1 401  ? 157.586 75.195  112.009 1.00 40.77  ? 401  GLU   C N     1 
ATOM   2006 C CA    . GLU   A 1 401  ? 158.905 74.572  111.938 1.00 42.80  ? 401  GLU   C CA    1 
ATOM   2007 C C     . GLU   A 1 401  ? 159.743 75.068  110.756 1.00 41.15  ? 401  GLU   C C     1 
ATOM   2008 O O     . GLU   A 1 401  ? 160.964 74.903  110.748 1.00 44.20  ? 401  GLU   C O     1 
ATOM   2009 C CB    . GLU   A 1 401  ? 158.770 73.049  111.862 1.00 45.37  ? 401  GLU   C CB    1 
ATOM   2010 C CG    . GLU   A 1 401  ? 158.309 72.395  113.156 1.00 51.42  ? 401  GLU   C CG    1 
ATOM   2011 C CD    . GLU   A 1 401  ? 158.098 70.907  113.026 1.00 59.16  ? 401  GLU   C CD    1 
ATOM   2012 O OE1   . GLU   A 1 401  ? 158.160 70.405  111.928 1.00 54.33  ? 401  GLU   C OE1   1 
ATOM   2013 O OE2   . GLU   A 1 401  ? 157.873 70.272  114.030 1.00 54.42  ? 401  GLU   C OE2   1 
ATOM   2014 N N     . ASN   A 1 402  ? 159.095 75.636  109.743 1.00 38.21  ? 402  ASN   C N     1 
ATOM   2015 C CA    . ASN   A 1 402  ? 159.792 76.132  108.564 1.00 33.61  ? 402  ASN   C CA    1 
ATOM   2016 C C     . ASN   A 1 402  ? 159.908 77.652  108.642 1.00 31.71  ? 402  ASN   C C     1 
ATOM   2017 O O     . ASN   A 1 402  ? 158.972 78.375  108.305 1.00 34.78  ? 402  ASN   C O     1 
ATOM   2018 C CB    . ASN   A 1 402  ? 159.074 75.682  107.301 1.00 32.60  ? 402  ASN   C CB    1 
ATOM   2019 C CG    . ASN   A 1 402  ? 159.780 76.069  106.030 1.00 33.98  ? 402  ASN   C CG    1 
ATOM   2020 O OD1   . ASN   A 1 402  ? 160.248 77.203  105.879 1.00 34.39  ? 402  ASN   C OD1   1 
ATOM   2021 N ND2   . ASN   A 1 402  ? 159.868 75.142  105.110 1.00 35.75  ? 402  ASN   C ND2   1 
ATOM   2022 N N     . GLU   A 1 403  ? 161.057 78.138  109.104 1.00 32.00  ? 403  GLU   C N     1 
ATOM   2023 C CA    . GLU   A 1 403  ? 161.214 79.563  109.385 1.00 32.44  ? 403  GLU   C CA    1 
ATOM   2024 C C     . GLU   A 1 403  ? 160.968 80.438  108.163 1.00 32.90  ? 403  GLU   C C     1 
ATOM   2025 O O     . GLU   A 1 403  ? 160.393 81.525  108.271 1.00 32.33  ? 403  GLU   C O     1 
ATOM   2026 C CB    . GLU   A 1 403  ? 162.615 79.838  109.932 1.00 35.14  ? 403  GLU   C CB    1 
ATOM   2027 C CG    . GLU   A 1 403  ? 162.869 81.291  110.317 1.00 39.58  ? 403  GLU   C CG    1 
ATOM   2028 C CD    . GLU   A 1 403  ? 162.028 81.746  111.476 1.00 43.49  ? 403  GLU   C CD    1 
ATOM   2029 O OE1   . GLU   A 1 403  ? 161.572 80.911  112.218 1.00 43.23  ? 403  GLU   C OE1   1 
ATOM   2030 O OE2   . GLU   A 1 403  ? 161.840 82.930  111.619 1.00 41.23  ? 403  GLU   C OE2   1 
ATOM   2031 N N     . VAL   A 1 404  ? 161.410 79.975  107.001 1.00 32.86  ? 404  VAL   C N     1 
ATOM   2032 C CA    . VAL   A 1 404  ? 161.262 80.766  105.791 1.00 28.92  ? 404  VAL   C CA    1 
ATOM   2033 C C     . VAL   A 1 404  ? 159.802 80.864  105.373 1.00 27.66  ? 404  VAL   C C     1 
ATOM   2034 O O     . VAL   A 1 404  ? 159.314 81.950  105.060 1.00 28.40  ? 404  VAL   C O     1 
ATOM   2035 C CB    . VAL   A 1 404  ? 162.094 80.164  104.648 1.00 28.21  ? 404  VAL   C CB    1 
ATOM   2036 C CG1   . VAL   A 1 404  ? 161.812 80.898  103.355 1.00 28.60  ? 404  VAL   C CG1   1 
ATOM   2037 C CG2   . VAL   A 1 404  ? 163.567 80.259  104.998 1.00 33.71  ? 404  VAL   C CG2   1 
ATOM   2038 N N     . LEU   A 1 405  ? 159.102 79.737  105.380 1.00 27.60  ? 405  LEU   C N     1 
ATOM   2039 C CA    . LEU   A 1 405  ? 157.702 79.734  104.984 1.00 24.82  ? 405  LEU   C CA    1 
ATOM   2040 C C     . LEU   A 1 405  ? 156.854 80.481  105.998 1.00 24.23  ? 405  LEU   C C     1 
ATOM   2041 O O     . LEU   A 1 405  ? 155.874 81.135  105.636 1.00 25.39  ? 405  LEU   C O     1 
ATOM   2042 C CB    . LEU   A 1 405  ? 157.177 78.307  104.830 1.00 24.25  ? 405  LEU   C CB    1 
ATOM   2043 C CG    . LEU   A 1 405  ? 155.746 78.172  104.266 1.00 26.37  ? 405  LEU   C CG    1 
ATOM   2044 C CD1   . LEU   A 1 405  ? 155.677 78.779  102.858 1.00 28.10  ? 405  LEU   C CD1   1 
ATOM   2045 C CD2   . LEU   A 1 405  ? 155.373 76.716  104.234 1.00 30.57  ? 405  LEU   C CD2   1 
ATOM   2046 N N     . PHE   A 1 406  ? 157.216 80.369  107.270 1.00 26.62  ? 406  PHE   C N     1 
ATOM   2047 C CA    . PHE   A 1 406  ? 156.481 81.053  108.319 1.00 24.24  ? 406  PHE   C CA    1 
ATOM   2048 C C     . PHE   A 1 406  ? 156.555 82.554  108.073 1.00 24.82  ? 406  PHE   C C     1 
ATOM   2049 O O     . PHE   A 1 406  ? 155.546 83.253  108.148 1.00 26.91  ? 406  PHE   C O     1 
ATOM   2050 C CB    . PHE   A 1 406  ? 157.035 80.689  109.694 1.00 29.97  ? 406  PHE   C CB    1 
ATOM   2051 C CG    . PHE   A 1 406  ? 156.240 81.232  110.834 1.00 29.95  ? 406  PHE   C CG    1 
ATOM   2052 C CD1   . PHE   A 1 406  ? 155.058 80.622  111.218 1.00 31.49  ? 406  PHE   C CD1   1 
ATOM   2053 C CD2   . PHE   A 1 406  ? 156.666 82.346  111.529 1.00 31.17  ? 406  PHE   C CD2   1 
ATOM   2054 C CE1   . PHE   A 1 406  ? 154.321 81.112  112.268 1.00 33.13  ? 406  PHE   C CE1   1 
ATOM   2055 C CE2   . PHE   A 1 406  ? 155.931 82.839  112.583 1.00 29.32  ? 406  PHE   C CE2   1 
ATOM   2056 C CZ    . PHE   A 1 406  ? 154.756 82.223  112.953 1.00 30.60  ? 406  PHE   C CZ    1 
ATOM   2057 N N     . THR   A 1 407  ? 157.751 83.046  107.746 1.00 24.45  ? 407  THR   C N     1 
ATOM   2058 C CA    . THR   A 1 407  ? 157.940 84.454  107.413 1.00 22.65  ? 407  THR   C CA    1 
ATOM   2059 C C     . THR   A 1 407  ? 157.104 84.855  106.198 1.00 20.87  ? 407  THR   C C     1 
ATOM   2060 O O     . THR   A 1 407  ? 156.449 85.897  106.198 1.00 19.85  ? 407  THR   C O     1 
ATOM   2061 C CB    . THR   A 1 407  ? 159.422 84.766  107.139 1.00 23.58  ? 407  THR   C CB    1 
ATOM   2062 O OG1   . THR   A 1 407  ? 160.188 84.532  108.334 1.00 29.71  ? 407  THR   C OG1   1 
ATOM   2063 C CG2   . THR   A 1 407  ? 159.585 86.215  106.690 1.00 24.37  ? 407  THR   C CG2   1 
ATOM   2064 N N     . MET   A 1 408  ? 157.107 84.017  105.163 1.00 21.69  ? 408  MET   C N     1 
ATOM   2065 C CA    . MET   A 1 408  ? 156.346 84.302  103.949 1.00 16.78  ? 408  MET   C CA    1 
ATOM   2066 C C     . MET   A 1 408  ? 154.846 84.398  104.211 1.00 15.50  ? 408  MET   C C     1 
ATOM   2067 O O     . MET   A 1 408  ? 154.151 85.182  103.564 1.00 17.88  ? 408  MET   C O     1 
ATOM   2068 C CB    . MET   A 1 408  ? 156.606 83.242  102.893 1.00 17.09  ? 408  MET   C CB    1 
ATOM   2069 C CG    . MET   A 1 408  ? 157.980 83.278  102.274 1.00 18.67  ? 408  MET   C CG    1 
ATOM   2070 S SD    . MET   A 1 408  ? 158.272 81.879  101.194 1.00 24.28  ? 408  MET   C SD    1 
ATOM   2071 C CE    . MET   A 1 408  ? 157.111 82.193  99.873  1.00 24.07  ? 408  MET   C CE    1 
ATOM   2072 N N     . CYS   A 1 409  ? 154.352 83.625  105.186 1.00 15.87  ? 409  CYS   C N     1 
ATOM   2073 C CA    . CYS   A 1 409  ? 152.925 83.613  105.525 1.00 13.41  ? 409  CYS   C CA    1 
ATOM   2074 C C     . CYS   A 1 409  ? 152.444 84.958  106.065 1.00 12.25  ? 409  CYS   C C     1 
ATOM   2075 O O     . CYS   A 1 409  ? 151.253 85.146  106.310 1.00 13.67  ? 409  CYS   C O     1 
ATOM   2076 C CB    . CYS   A 1 409  ? 152.618 82.519  106.547 1.00 16.66  ? 409  CYS   C CB    1 
ATOM   2077 S SG    . CYS   A 1 409  ? 152.758 80.835  105.891 1.00 26.46  ? 409  CYS   C SG    1 
ATOM   2078 N N     . PHE   A 1 410  ? 153.366 85.908  106.188 1.00 13.76  ? 410  PHE   C N     1 
ATOM   2079 C CA    . PHE   A 1 410  ? 153.054 87.295  106.502 1.00 12.10  ? 410  PHE   C CA    1 
ATOM   2080 C C     . PHE   A 1 410  ? 151.966 87.810  105.574 1.00 9.78   ? 410  PHE   C C     1 
ATOM   2081 O O     . PHE   A 1 410  ? 151.058 88.530  105.996 1.00 12.05  ? 410  PHE   C O     1 
ATOM   2082 C CB    . PHE   A 1 410  ? 154.321 88.142  106.355 1.00 13.23  ? 410  PHE   C CB    1 
ATOM   2083 C CG    . PHE   A 1 410  ? 154.124 89.622  106.430 1.00 9.63   ? 410  PHE   C CG    1 
ATOM   2084 C CD1   . PHE   A 1 410  ? 153.822 90.238  107.618 1.00 13.41  ? 410  PHE   C CD1   1 
ATOM   2085 C CD2   . PHE   A 1 410  ? 154.271 90.406  105.298 1.00 10.85  ? 410  PHE   C CD2   1 
ATOM   2086 C CE1   . PHE   A 1 410  ? 153.662 91.603  107.684 1.00 13.95  ? 410  PHE   C CE1   1 
ATOM   2087 C CE2   . PHE   A 1 410  ? 154.114 91.771  105.358 1.00 11.98  ? 410  PHE   C CE2   1 
ATOM   2088 C CZ    . PHE   A 1 410  ? 153.809 92.371  106.551 1.00 11.15  ? 410  PHE   C CZ    1 
ATOM   2089 N N     . ILE   A 1 411  ? 152.079 87.458  104.297 1.00 10.01  ? 411  ILE   C N     1 
ATOM   2090 C CA    . ILE   A 1 411  ? 151.113 87.863  103.291 1.00 8.25   ? 411  ILE   C CA    1 
ATOM   2091 C C     . ILE   A 1 411  ? 149.941 86.872  103.290 1.00 9.60   ? 411  ILE   C C     1 
ATOM   2092 O O     . ILE   A 1 411  ? 150.148 85.698  102.997 1.00 8.76   ? 411  ILE   C O     1 
ATOM   2093 C CB    . ILE   A 1 411  ? 151.772 87.871  101.899 1.00 8.11   ? 411  ILE   C CB    1 
ATOM   2094 C CG1   . ILE   A 1 411  ? 152.862 88.892  101.860 1.00 8.90   ? 411  ILE   C CG1   1 
ATOM   2095 C CG2   . ILE   A 1 411  ? 150.786 88.162  100.829 1.00 12.44  ? 411  ILE   C CG2   1 
ATOM   2096 C CD1   . ILE   A 1 411  ? 154.212 88.308  102.041 1.00 12.37  ? 411  ILE   C CD1   1 
ATOM   2097 N N     . PRO   A 1 412  ? 148.709 87.322  103.569 1.00 7.78   ? 412  PRO   C N     1 
ATOM   2098 C CA    . PRO   A 1 412  ? 147.502 86.520  103.636 1.00 6.96   ? 412  PRO   C CA    1 
ATOM   2099 C C     . PRO   A 1 412  ? 147.356 85.576  102.455 1.00 8.94   ? 412  PRO   C C     1 
ATOM   2100 O O     . PRO   A 1 412  ? 146.982 84.416  102.632 1.00 13.89  ? 412  PRO   C O     1 
ATOM   2101 C CB    . PRO   A 1 412  ? 146.421 87.592  103.641 1.00 7.81   ? 412  PRO   C CB    1 
ATOM   2102 C CG    . PRO   A 1 412  ? 147.063 88.737  104.353 1.00 7.47   ? 412  PRO   C CG    1 
ATOM   2103 C CD    . PRO   A 1 412  ? 148.493 88.732  103.879 1.00 7.70   ? 412  PRO   C CD    1 
ATOM   2104 N N     . LEU   A 1 413  ? 147.698 86.039  101.257 1.00 10.45  ? 413  LEU   C N     1 
ATOM   2105 C CA    . LEU   A 1 413  ? 147.616 85.186  100.082 1.00 10.07  ? 413  LEU   C CA    1 
ATOM   2106 C C     . LEU   A 1 413  ? 148.493 83.950  100.224 1.00 13.60  ? 413  LEU   C C     1 
ATOM   2107 O O     . LEU   A 1 413  ? 148.124 82.866  99.774  1.00 18.80  ? 413  LEU   C O     1 
ATOM   2108 C CB    . LEU   A 1 413  ? 148.014 85.966  98.826  1.00 8.97   ? 413  LEU   C CB    1 
ATOM   2109 C CG    . LEU   A 1 413  ? 148.013 85.186  97.498  1.00 10.46  ? 413  LEU   C CG    1 
ATOM   2110 C CD1   . LEU   A 1 413  ? 146.626 84.639  97.204  1.00 10.77  ? 413  LEU   C CD1   1 
ATOM   2111 C CD2   . LEU   A 1 413  ? 148.459 86.120  96.383  1.00 14.96  ? 413  LEU   C CD2   1 
ATOM   2112 N N     . VAL   A 1 414  ? 149.672 84.105  100.819 1.00 11.53  ? 414  VAL   C N     1 
ATOM   2113 C CA    . VAL   A 1 414  ? 150.591 82.987  100.927 1.00 9.22   ? 414  VAL   C CA    1 
ATOM   2114 C C     . VAL   A 1 414  ? 150.076 81.962  101.913 1.00 15.32  ? 414  VAL   C C     1 
ATOM   2115 O O     . VAL   A 1 414  ? 150.129 80.761  101.646 1.00 20.03  ? 414  VAL   C O     1 
ATOM   2116 C CB    . VAL   A 1 414  ? 151.992 83.446  101.349 1.00 9.34   ? 414  VAL   C CB    1 
ATOM   2117 C CG1   . VAL   A 1 414  ? 152.885 82.230  101.607 1.00 14.51  ? 414  VAL   C CG1   1 
ATOM   2118 C CG2   . VAL   A 1 414  ? 152.577 84.317  100.265 1.00 11.68  ? 414  VAL   C CG2   1 
ATOM   2119 N N     . CYS   A 1 415  ? 149.586 82.424  103.059 1.00 16.26  ? 415  CYS   C N     1 
ATOM   2120 C CA    . CYS   A 1 415  ? 149.100 81.474  104.049 1.00 16.80  ? 415  CYS   C CA    1 
ATOM   2121 C C     . CYS   A 1 415  ? 147.862 80.756  103.527 1.00 18.62  ? 415  CYS   C C     1 
ATOM   2122 O O     . CYS   A 1 415  ? 147.648 79.584  103.835 1.00 24.47  ? 415  CYS   C O     1 
ATOM   2123 C CB    . CYS   A 1 415  ? 148.783 82.160  105.378 1.00 14.50  ? 415  CYS   C CB    1 
ATOM   2124 S SG    . CYS   A 1 415  ? 147.294 83.153  105.375 1.00 18.15  ? 415  CYS   C SG    1 
ATOM   2125 N N     . TRP   A 1 416  ? 147.078 81.433  102.685 1.00 17.90  ? 416  TRP   C N     1 
ATOM   2126 C CA    . TRP   A 1 416  ? 145.927 80.801  102.058 1.00 19.07  ? 416  TRP   C CA    1 
ATOM   2127 C C     . TRP   A 1 416  ? 146.349 79.680  101.116 1.00 21.00  ? 416  TRP   C C     1 
ATOM   2128 O O     . TRP   A 1 416  ? 145.785 78.585  101.154 1.00 28.13  ? 416  TRP   C O     1 
ATOM   2129 C CB    . TRP   A 1 416  ? 145.069 81.802  101.299 1.00 16.77  ? 416  TRP   C CB    1 
ATOM   2130 C CG    . TRP   A 1 416  ? 143.985 81.120  100.557 1.00 17.46  ? 416  TRP   C CG    1 
ATOM   2131 C CD1   . TRP   A 1 416  ? 142.816 80.670  101.069 1.00 22.56  ? 416  TRP   C CD1   1 
ATOM   2132 C CD2   . TRP   A 1 416  ? 143.967 80.777  99.158  1.00 20.68  ? 416  TRP   C CD2   1 
ATOM   2133 N NE1   . TRP   A 1 416  ? 142.082 80.065  100.092 1.00 28.88  ? 416  TRP   C NE1   1 
ATOM   2134 C CE2   . TRP   A 1 416  ? 142.773 80.121  98.919  1.00 24.41  ? 416  TRP   C CE2   1 
ATOM   2135 C CE3   . TRP   A 1 416  ? 144.857 80.968  98.110  1.00 25.15  ? 416  TRP   C CE3   1 
ATOM   2136 C CZ2   . TRP   A 1 416  ? 142.444 79.638  97.679  1.00 26.98  ? 416  TRP   C CZ2   1 
ATOM   2137 C CZ3   . TRP   A 1 416  ? 144.527 80.485  96.855  1.00 24.08  ? 416  TRP   C CZ3   1 
ATOM   2138 C CH2   . TRP   A 1 416  ? 143.347 79.834  96.648  1.00 25.30  ? 416  TRP   C CH2   1 
ATOM   2139 N N     . ILE   A 1 417  ? 147.347 79.950  100.271 1.00 19.12  ? 417  ILE   C N     1 
ATOM   2140 C CA    . ILE   A 1 417  ? 147.808 78.947  99.319  1.00 19.25  ? 417  ILE   C CA    1 
ATOM   2141 C C     . ILE   A 1 417  ? 148.316 77.718  100.060 1.00 23.33  ? 417  ILE   C C     1 
ATOM   2142 O O     . ILE   A 1 417  ? 148.020 76.583  99.677  1.00 28.37  ? 417  ILE   C O     1 
ATOM   2143 C CB    . ILE   A 1 417  ? 148.924 79.495  98.399  1.00 15.60  ? 417  ILE   C CB    1 
ATOM   2144 C CG1   . ILE   A 1 417  ? 148.368 80.577  97.470  1.00 16.60  ? 417  ILE   C CG1   1 
ATOM   2145 C CG2   . ILE   A 1 417  ? 149.501 78.361  97.582  1.00 20.30  ? 417  ILE   C CG2   1 
ATOM   2146 C CD1   . ILE   A 1 417  ? 149.423 81.375  96.732  1.00 17.97  ? 417  ILE   C CD1   1 
ATOM   2147 N N     . VAL   A 1 418  ? 149.082 77.943  101.125 1.00 22.48  ? 418  VAL   C N     1 
ATOM   2148 C CA    . VAL   A 1 418  ? 149.615 76.846  101.918 1.00 20.10  ? 418  VAL   C CA    1 
ATOM   2149 C C     . VAL   A 1 418  ? 148.499 76.064  102.603 1.00 27.95  ? 418  VAL   C C     1 
ATOM   2150 O O     . VAL   A 1 418  ? 148.520 74.830  102.613 1.00 33.62  ? 418  VAL   C O     1 
ATOM   2151 C CB    . VAL   A 1 418  ? 150.604 77.373  102.972 1.00 19.58  ? 418  VAL   C CB    1 
ATOM   2152 C CG1   . VAL   A 1 418  ? 151.016 76.256  103.906 1.00 32.54  ? 418  VAL   C CG1   1 
ATOM   2153 C CG2   . VAL   A 1 418  ? 151.828 77.948  102.287 1.00 24.28  ? 418  VAL   C CG2   1 
ATOM   2154 N N     . CYS   A 1 419  ? 147.525 76.770  103.179 1.00 27.74  ? 419  CYS   C N     1 
ATOM   2155 C CA    . CYS   A 1 419  ? 146.418 76.110  103.862 1.00 28.65  ? 419  CYS   C CA    1 
ATOM   2156 C C     . CYS   A 1 419  ? 145.624 75.210  102.930 1.00 31.50  ? 419  CYS   C C     1 
ATOM   2157 O O     . CYS   A 1 419  ? 145.286 74.085  103.296 1.00 37.75  ? 419  CYS   C O     1 
ATOM   2158 C CB    . CYS   A 1 419  ? 145.459 77.128  104.465 1.00 29.10  ? 419  CYS   C CB    1 
ATOM   2159 S SG    . CYS   A 1 419  ? 146.093 77.999  105.874 1.00 31.27  ? 419  CYS   C SG    1 
ATOM   2160 N N     . THR   A 1 420  ? 145.336 75.693  101.721 1.00 30.55  ? 420  THR   C N     1 
ATOM   2161 C CA    . THR   A 1 420  ? 144.575 74.897  100.765 1.00 29.74  ? 420  THR   C CA    1 
ATOM   2162 C C     . THR   A 1 420  ? 145.336 73.630  100.410 1.00 37.75  ? 420  THR   C C     1 
ATOM   2163 O O     . THR   A 1 420  ? 144.756 72.544  100.352 1.00 44.25  ? 420  THR   C O     1 
ATOM   2164 C CB    . THR   A 1 420  ? 144.255 75.693  99.488  1.00 27.15  ? 420  THR   C CB    1 
ATOM   2165 O OG1   . THR   A 1 420  ? 143.452 76.831  99.823  1.00 28.01  ? 420  THR   C OG1   1 
ATOM   2166 C CG2   . THR   A 1 420  ? 143.486 74.814  98.502  1.00 32.25  ? 420  THR   C CG2   1 
ATOM   2167 N N     . GLY   A 1 421  ? 146.639 73.762  100.183 1.00 35.43  ? 421  GLY   C N     1 
ATOM   2168 C CA    . GLY   A 1 421  ? 147.468 72.611  99.858  1.00 38.20  ? 421  GLY   C CA    1 
ATOM   2169 C C     . GLY   A 1 421  ? 147.426 71.570  100.974 1.00 43.65  ? 421  GLY   C C     1 
ATOM   2170 O O     . GLY   A 1 421  ? 147.242 70.378  100.715 1.00 50.31  ? 421  GLY   C O     1 
ATOM   2171 N N     . LEU   A 1 422  ? 147.593 72.015  102.219 1.00 37.92  ? 422  LEU   C N     1 
ATOM   2172 C CA    . LEU   A 1 422  ? 147.557 71.094  103.348 1.00 41.21  ? 422  LEU   C CA    1 
ATOM   2173 C C     . LEU   A 1 422  ? 146.176 70.477  103.525 1.00 47.29  ? 422  LEU   C C     1 
ATOM   2174 O O     . LEU   A 1 422  ? 146.066 69.288  103.822 1.00 51.39  ? 422  LEU   C O     1 
ATOM   2175 C CB    . LEU   A 1 422  ? 147.971 71.805  104.641 1.00 37.74  ? 422  LEU   C CB    1 
ATOM   2176 C CG    . LEU   A 1 422  ? 149.458 72.201  104.764 1.00 36.98  ? 422  LEU   C CG    1 
ATOM   2177 C CD1   . LEU   A 1 422  ? 149.629 73.086  105.988 1.00 35.40  ? 422  LEU   C CD1   1 
ATOM   2178 C CD2   . LEU   A 1 422  ? 150.330 70.941  104.889 1.00 47.96  ? 422  LEU   C CD2   1 
ATOM   2179 N N     . LYS   A 1 423  ? 145.123 71.268  103.328 1.00 44.42  ? 423  LYS   C N     1 
ATOM   2180 C CA    . LYS   A 1 423  ? 143.765 70.752  103.465 1.00 46.94  ? 423  LYS   C CA    1 
ATOM   2181 C C     . LYS   A 1 423  ? 143.526 69.604  102.500 1.00 48.68  ? 423  LYS   C C     1 
ATOM   2182 O O     . LYS   A 1 423  ? 142.938 68.586  102.870 1.00 58.67  ? 423  LYS   C O     1 
ATOM   2183 C CB    . LYS   A 1 423  ? 142.731 71.851  103.223 1.00 44.96  ? 423  LYS   C CB    1 
ATOM   2184 C CG    . LYS   A 1 423  ? 141.276 71.407  103.421 1.00 49.50  ? 423  LYS   C CG    1 
ATOM   2185 C CD    . LYS   A 1 423  ? 140.306 72.575  103.228 1.00 50.12  ? 423  LYS   C CD    1 
ATOM   2186 C CE    . LYS   A 1 423  ? 138.871 72.205  103.615 1.00 56.21  ? 423  LYS   C CE    1 
ATOM   2187 N NZ    . LYS   A 1 423  ? 138.282 71.173  102.710 1.00 62.49  ? 423  LYS   C NZ    1 
ATOM   2188 N N     . GLN   A 1 424  ? 143.990 69.764  101.264 1.00 48.85  ? 424  GLN   C N     1 
ATOM   2189 C CA    . GLN   A 1 424  ? 143.823 68.723  100.261 1.00 54.24  ? 424  GLN   C CA    1 
ATOM   2190 C C     . GLN   A 1 424  ? 144.580 67.462  100.662 1.00 55.86  ? 424  GLN   C C     1 
ATOM   2191 O O     . GLN   A 1 424  ? 144.067 66.350  100.513 1.00 60.93  ? 424  GLN   C O     1 
ATOM   2192 C CB    . GLN   A 1 424  ? 144.306 69.227  98.901  1.00 53.54  ? 424  GLN   C CB    1 
ATOM   2193 C CG    . GLN   A 1 424  ? 143.418 70.300  98.298  1.00 55.42  ? 424  GLN   C CG    1 
ATOM   2194 C CD    . GLN   A 1 424  ? 144.044 70.962  97.090  1.00 68.09  ? 424  GLN   C CD    1 
ATOM   2195 O OE1   . GLN   A 1 424  ? 145.239 70.801  96.823  1.00 64.90  ? 424  GLN   C OE1   1 
ATOM   2196 N NE2   . GLN   A 1 424  ? 143.241 71.715  96.354  1.00 70.16  ? 424  GLN   C NE2   1 
ATOM   2197 N N     . GLN   A 1 425  ? 145.777 67.632  101.218 1.00 53.02  ? 425  GLN   C N     1 
ATOM   2198 C CA    . GLN   A 1 425  ? 146.547 66.490  101.688 1.00 57.28  ? 425  GLN   C CA    1 
ATOM   2199 C C     . GLN   A 1 425  ? 145.860 65.794  102.859 1.00 63.12  ? 425  GLN   C C     1 
ATOM   2200 O O     . GLN   A 1 425  ? 145.901 64.568  102.971 1.00 67.60  ? 425  GLN   C O     1 
ATOM   2201 C CB    . GLN   A 1 425  ? 147.957 66.909  102.092 1.00 57.15  ? 425  GLN   C CB    1 
ATOM   2202 C CG    . GLN   A 1 425  ? 148.863 67.265  100.946 1.00 57.43  ? 425  GLN   C CG    1 
ATOM   2203 C CD    . GLN   A 1 425  ? 150.269 67.546  101.422 1.00 57.02  ? 425  GLN   C CD    1 
ATOM   2204 O OE1   . GLN   A 1 425  ? 151.034 66.612  101.715 1.00 61.33  ? 425  GLN   C OE1   1 
ATOM   2205 N NE2   . GLN   A 1 425  ? 150.617 68.820  101.511 1.00 54.50  ? 425  GLN   C NE2   1 
ATOM   2206 N N     . MET   A 1 426  ? 145.223 66.564  103.734 1.00 57.68  ? 426  MET   C N     1 
ATOM   2207 C CA    . MET   A 1 426  ? 144.512 65.969  104.859 1.00 59.97  ? 426  MET   C CA    1 
ATOM   2208 C C     . MET   A 1 426  ? 143.373 65.090  104.364 1.00 63.57  ? 426  MET   C C     1 
ATOM   2209 O O     . MET   A 1 426  ? 143.223 63.947  104.799 1.00 64.98  ? 426  MET   C O     1 
ATOM   2210 C CB    . MET   A 1 426  ? 143.975 67.057  105.788 1.00 60.60  ? 426  MET   C CB    1 
ATOM   2211 C CG    . MET   A 1 426  ? 145.035 67.798  106.565 1.00 59.57  ? 426  MET   C CG    1 
ATOM   2212 S SD    . MET   A 1 426  ? 144.386 69.166  107.496 1.00 61.57  ? 426  MET   C SD    1 
ATOM   2213 C CE    . MET   A 1 426  ? 145.888 69.814  108.217 1.00 54.99  ? 426  MET   C CE    1 
ATOM   2214 N N     . GLU   A 1 427  ? 142.588 65.614  103.426 1.00 60.66  ? 427  GLU   C N     1 
ATOM   2215 C CA    . GLU   A 1 427  ? 141.434 64.898  102.889 1.00 64.83  ? 427  GLU   C CA    1 
ATOM   2216 C C     . GLU   A 1 427  ? 141.838 63.613  102.180 1.00 65.02  ? 427  GLU   C C     1 
ATOM   2217 O O     . GLU   A 1 427  ? 141.137 62.603  102.259 1.00 68.44  ? 427  GLU   C O     1 
ATOM   2218 C CB    . GLU   A 1 427  ? 140.657 65.789  101.919 1.00 65.47  ? 427  GLU   C CB    1 
ATOM   2219 C CG    . GLU   A 1 427  ? 139.918 66.944  102.574 1.00 65.91  ? 427  GLU   C CG    1 
ATOM   2220 C CD    . GLU   A 1 427  ? 139.244 67.843  101.573 1.00 68.27  ? 427  GLU   C CD    1 
ATOM   2221 O OE1   . GLU   A 1 427  ? 139.362 67.583  100.398 1.00 68.32  ? 427  GLU   C OE1   1 
ATOM   2222 O OE2   . GLU   A 1 427  ? 138.619 68.798  101.986 1.00 67.85  ? 427  GLU   C OE2   1 
ATOM   2223 N N     . SER   A 1 428  ? 142.979 63.648  101.503 1.00 64.92  ? 428  SER   C N     1 
ATOM   2224 C CA    . SER   A 1 428  ? 143.468 62.501  100.750 1.00 67.47  ? 428  SER   C CA    1 
ATOM   2225 C C     . SER   A 1 428  ? 144.266 61.511  101.602 1.00 71.78  ? 428  SER   C C     1 
ATOM   2226 O O     . SER   A 1 428  ? 144.728 60.490  101.091 1.00 71.35  ? 428  SER   C O     1 
ATOM   2227 C CB    . SER   A 1 428  ? 144.316 62.969  99.583  1.00 68.46  ? 428  SER   C CB    1 
ATOM   2228 O OG    . SER   A 1 428  ? 143.544 63.652  98.631  1.00 67.75  ? 428  SER   C OG    1 
ATOM   2229 N N     . GLY   A 1 429  ? 144.450 61.815  102.889 1.00 67.45  ? 429  GLY   C N     1 
ATOM   2230 C CA    . GLY   A 1 429  ? 145.194 60.926  103.780 1.00 68.77  ? 429  GLY   C CA    1 
ATOM   2231 C C     . GLY   A 1 429  ? 146.703 60.938  103.532 1.00 69.42  ? 429  GLY   C C     1 
ATOM   2232 O O     . GLY   A 1 429  ? 147.364 59.905  103.651 1.00 69.93  ? 429  GLY   C O     1 
ATOM   2233 N N     . LYS   A 1 430  ? 147.246 62.096  103.171 1.00 67.36  ? 430  LYS   C N     1 
ATOM   2234 C CA    . LYS   A 1 430  ? 148.669 62.217  102.876 1.00 70.19  ? 430  LYS   C CA    1 
ATOM   2235 C C     . LYS   A 1 430  ? 149.463 62.678  104.099 1.00 68.62  ? 430  LYS   C C     1 
ATOM   2236 O O     . LYS   A 1 430  ? 148.896 63.003  105.141 1.00 66.60  ? 430  LYS   C O     1 
ATOM   2237 C CB    . LYS   A 1 430  ? 148.890 63.162  101.696 1.00 67.90  ? 430  LYS   C CB    1 
ATOM   2238 C CG    . LYS   A 1 430  ? 148.140 62.769  100.422 1.00 69.51  ? 430  LYS   C CG    1 
ATOM   2239 C CD    . LYS   A 1 430  ? 148.624 61.432  99.864  1.00 74.85  ? 430  LYS   C CD    1 
ATOM   2240 C CE    . LYS   A 1 430  ? 147.974 61.122  98.523  1.00 79.59  ? 430  LYS   C CE    1 
ATOM   2241 N NZ    . LYS   A 1 430  ? 148.385 59.789  97.999  1.00 83.26  ? 430  LYS   C NZ    1 
ATOM   2242 N N     . SER   A 1 431  ? 150.788 62.677  103.958 1.00 68.89  ? 431  SER   C N     1 
ATOM   2243 C CA    . SER   A 1 431  ? 151.732 62.999  105.033 1.00 69.12  ? 431  SER   C CA    1 
ATOM   2244 C C     . SER   A 1 431  ? 151.767 64.477  105.426 1.00 66.54  ? 431  SER   C C     1 
ATOM   2245 O O     . SER   A 1 431  ? 152.422 64.844  106.402 1.00 65.40  ? 431  SER   C O     1 
ATOM   2246 C CB    . SER   A 1 431  ? 153.120 62.555  104.619 1.00 70.31  ? 431  SER   C CB    1 
ATOM   2247 O OG    . SER   A 1 431  ? 153.567 63.284  103.508 1.00 66.88  ? 431  SER   C OG    1 
ATOM   2248 N N     . LEU   A 1 432  ? 151.080 65.316  104.659 1.00 64.83  ? 432  LEU   C N     1 
ATOM   2249 C CA    . LEU   A 1 432  ? 151.038 66.761  104.894 1.00 63.88  ? 432  LEU   C CA    1 
ATOM   2250 C C     . LEU   A 1 432  ? 152.410 67.391  104.700 1.00 62.03  ? 432  LEU   C C     1 
ATOM   2251 O O     . LEU   A 1 432  ? 152.924 68.079  105.582 1.00 58.37  ? 432  LEU   C O     1 
ATOM   2252 C CB    . LEU   A 1 432  ? 150.543 67.079  106.313 1.00 64.06  ? 432  LEU   C CB    1 
ATOM   2253 C CG    . LEU   A 1 432  ? 149.233 66.418  106.753 1.00 63.91  ? 432  LEU   C CG    1 
ATOM   2254 C CD1   . LEU   A 1 432  ? 148.857 66.938  108.136 1.00 63.06  ? 432  LEU   C CD1   1 
ATOM   2255 C CD2   . LEU   A 1 432  ? 148.154 66.703  105.747 1.00 60.14  ? 432  LEU   C CD2   1 
ATOM   2256 N N     . ALA   A 1 433  ? 153.011 67.131  103.546 1.00 61.41  ? 433  ALA   C N     1 
ATOM   2257 C CA    . ALA   A 1 433  ? 154.331 67.656  103.236 1.00 59.02  ? 433  ALA   C CA    1 
ATOM   2258 C C     . ALA   A 1 433  ? 154.257 69.128  102.854 1.00 53.21  ? 433  ALA   C C     1 
ATOM   2259 O O     . ALA   A 1 433  ? 153.299 69.570  102.219 1.00 52.20  ? 433  ALA   C O     1 
ATOM   2260 C CB    . ALA   A 1 433  ? 154.959 66.856  102.107 1.00 59.26  ? 433  ALA   C CB    1 
ATOM   2261 N N     . GLN   A 1 434  ? 155.291 69.876  103.226 1.00 49.81  ? 434  GLN   C N     1 
ATOM   2262 C CA    . GLN   A 1 434  ? 155.437 71.270  102.822 1.00 46.03  ? 434  GLN   C CA    1 
ATOM   2263 C C     . GLN   A 1 434  ? 156.879 71.720  103.012 1.00 44.68  ? 434  GLN   C C     1 
ATOM   2264 O O     . GLN   A 1 434  ? 157.321 71.945  104.138 1.00 41.08  ? 434  GLN   C O     1 
ATOM   2265 C CB    . GLN   A 1 434  ? 154.481 72.168  103.607 1.00 42.49  ? 434  GLN   C CB    1 
ATOM   2266 C CG    . GLN   A 1 434  ? 154.652 73.644  103.322 1.00 38.39  ? 434  GLN   C CG    1 
ATOM   2267 C CD    . GLN   A 1 434  ? 154.435 74.000  101.862 1.00 40.65  ? 434  GLN   C CD    1 
ATOM   2268 O OE1   . GLN   A 1 434  ? 155.389 74.036  101.070 1.00 42.26  ? 434  GLN   C OE1   1 
ATOM   2269 N NE2   . GLN   A 1 434  ? 153.183 74.263  101.498 1.00 35.41  ? 434  GLN   C NE2   1 
ATOM   2270 N N     . THR   A 1 435  ? 157.619 71.809  101.913 1.00 44.97  ? 435  THR   C N     1 
ATOM   2271 C CA    . THR   A 1 435  ? 159.042 72.115  101.972 1.00 43.87  ? 435  THR   C CA    1 
ATOM   2272 C C     . THR   A 1 435  ? 159.423 73.363  101.177 1.00 42.71  ? 435  THR   C C     1 
ATOM   2273 O O     . THR   A 1 435  ? 160.604 73.603  100.927 1.00 42.87  ? 435  THR   C O     1 
ATOM   2274 C CB    . THR   A 1 435  ? 159.868 70.922  101.458 1.00 44.61  ? 435  THR   C CB    1 
ATOM   2275 O OG1   . THR   A 1 435  ? 159.512 70.646  100.096 1.00 45.43  ? 435  THR   C OG1   1 
ATOM   2276 C CG2   . THR   A 1 435  ? 159.583 69.691  102.302 1.00 45.63  ? 435  THR   C CG2   1 
ATOM   2277 N N     . SER   A 1 436  ? 158.431 74.139  100.745 1.00 39.94  ? 436  SER   C N     1 
ATOM   2278 C CA    . SER   A 1 436  ? 158.710 75.314  99.925  1.00 34.14  ? 436  SER   C CA    1 
ATOM   2279 C C     . SER   A 1 436  ? 159.449 76.408  100.692 1.00 31.61  ? 436  SER   C C     1 
ATOM   2280 O O     . SER   A 1 436  ? 159.122 76.705  101.840 1.00 33.32  ? 436  SER   C O     1 
ATOM   2281 C CB    . SER   A 1 436  ? 157.419 75.859  99.360  1.00 35.67  ? 436  SER   C CB    1 
ATOM   2282 O OG    . SER   A 1 436  ? 156.844 74.946  98.465  1.00 36.62  ? 436  SER   C OG    1 
ATOM   2283 N N     . LYS   A 1 437  ? 160.437 77.022  100.036 1.00 30.70  ? 437  LYS   C N     1 
ATOM   2284 C CA    . LYS   A 1 437  ? 161.214 78.114  100.623 1.00 29.51  ? 437  LYS   C CA    1 
ATOM   2285 C C     . LYS   A 1 437  ? 161.044 79.436  99.870  1.00 27.95  ? 437  LYS   C C     1 
ATOM   2286 O O     . LYS   A 1 437  ? 161.228 80.511  100.436 1.00 28.79  ? 437  LYS   C O     1 
ATOM   2287 C CB    . LYS   A 1 437  ? 162.694 77.739  100.667 1.00 31.20  ? 437  LYS   C CB    1 
ATOM   2288 C CG    . LYS   A 1 437  ? 163.010 76.564  101.574 1.00 42.04  ? 437  LYS   C CG    1 
ATOM   2289 C CD    . LYS   A 1 437  ? 164.498 76.251  101.582 1.00 49.02  ? 437  LYS   C CD    1 
ATOM   2290 C CE    . LYS   A 1 437  ? 164.807 75.058  102.476 1.00 50.40  ? 437  LYS   C CE    1 
ATOM   2291 N NZ    . LYS   A 1 437  ? 166.256 74.716  102.462 1.00 61.07  ? 437  LYS   C NZ    1 
ATOM   2292 N N     . THR   A 1 438  ? 160.737 79.349  98.583  1.00 25.69  ? 438  THR   C N     1 
ATOM   2293 C CA    . THR   A 1 438  ? 160.645 80.528  97.729  1.00 21.56  ? 438  THR   C CA    1 
ATOM   2294 C C     . THR   A 1 438  ? 159.210 80.768  97.284  1.00 24.05  ? 438  THR   C C     1 
ATOM   2295 O O     . THR   A 1 438  ? 158.353 79.898  97.450  1.00 27.59  ? 438  THR   C O     1 
ATOM   2296 C CB    . THR   A 1 438  ? 161.553 80.372  96.498  1.00 22.33  ? 438  THR   C CB    1 
ATOM   2297 O OG1   . THR   A 1 438  ? 161.102 79.261  95.706  1.00 25.46  ? 438  THR   C OG1   1 
ATOM   2298 C CG2   . THR   A 1 438  ? 162.991 80.136  96.928  1.00 25.41  ? 438  THR   C CG2   1 
ATOM   2299 N N     . THR   A 1 439  ? 158.944 81.944  96.714  1.00 22.74  ? 439  THR   C N     1 
ATOM   2300 C CA    . THR   A 1 439  ? 157.599 82.255  96.239  1.00 18.57  ? 439  THR   C CA    1 
ATOM   2301 C C     . THR   A 1 439  ? 157.217 81.300  95.128  1.00 21.12  ? 439  THR   C C     1 
ATOM   2302 O O     . THR   A 1 439  ? 156.097 80.787  95.093  1.00 23.08  ? 439  THR   C O     1 
ATOM   2303 C CB    . THR   A 1 439  ? 157.486 83.712  95.742  1.00 21.31  ? 439  THR   C CB    1 
ATOM   2304 O OG1   . THR   A 1 439  ? 157.775 84.611  96.822  1.00 23.58  ? 439  THR   C OG1   1 
ATOM   2305 C CG2   . THR   A 1 439  ? 156.072 83.986  95.234  1.00 21.22  ? 439  THR   C CG2   1 
ATOM   2306 N N     . THR   A 1 440  ? 158.155 81.044  94.226  1.00 21.90  ? 440  THR   C N     1 
ATOM   2307 C CA    . THR   A 1 440  ? 157.899 80.140  93.123  1.00 19.90  ? 440  THR   C CA    1 
ATOM   2308 C C     . THR   A 1 440  ? 157.569 78.752  93.652  1.00 24.98  ? 440  THR   C C     1 
ATOM   2309 O O     . THR   A 1 440  ? 156.606 78.128  93.216  1.00 32.03  ? 440  THR   C O     1 
ATOM   2310 C CB    . THR   A 1 440  ? 159.103 80.066  92.169  1.00 19.04  ? 440  THR   C CB    1 
ATOM   2311 O OG1   . THR   A 1 440  ? 159.369 81.370  91.644  1.00 23.38  ? 440  THR   C OG1   1 
ATOM   2312 C CG2   . THR   A 1 440  ? 158.806 79.124  91.017  1.00 23.27  ? 440  THR   C CG2   1 
ATOM   2313 N N     . ALA   A 1 441  ? 158.349 78.278  94.622  1.00 24.63  ? 441  ALA   C N     1 
ATOM   2314 C CA    . ALA   A 1 441  ? 158.129 76.941  95.164  1.00 24.90  ? 441  ALA   C CA    1 
ATOM   2315 C C     . ALA   A 1 441  ? 156.723 76.790  95.737  1.00 25.99  ? 441  ALA   C C     1 
ATOM   2316 O O     . ALA   A 1 441  ? 156.101 75.736  95.581  1.00 31.33  ? 441  ALA   C O     1 
ATOM   2317 C CB    . ALA   A 1 441  ? 159.158 76.642  96.240  1.00 28.87  ? 441  ALA   C CB    1 
ATOM   2318 N N     . VAL   A 1 442  ? 156.208 77.833  96.386  1.00 25.20  ? 442  VAL   C N     1 
ATOM   2319 C CA    . VAL   A 1 442  ? 154.866 77.767  96.956  1.00 23.58  ? 442  VAL   C CA    1 
ATOM   2320 C C     . VAL   A 1 442  ? 153.807 77.645  95.864  1.00 25.24  ? 442  VAL   C C     1 
ATOM   2321 O O     . VAL   A 1 442  ? 152.897 76.821  95.961  1.00 30.26  ? 442  VAL   C O     1 
ATOM   2322 C CB    . VAL   A 1 442  ? 154.579 79.002  97.839  1.00 20.05  ? 442  VAL   C CB    1 
ATOM   2323 C CG1   . VAL   A 1 442  ? 153.115 79.036  98.257  1.00 17.46  ? 442  VAL   C CG1   1 
ATOM   2324 C CG2   . VAL   A 1 442  ? 155.461 78.954  99.075  1.00 22.72  ? 442  VAL   C CG2   1 
ATOM   2325 N N     . TYR   A 1 443  ? 153.936 78.462  94.819  1.00 23.40  ? 443  TYR   C N     1 
ATOM   2326 C CA    . TYR   A 1 443  ? 152.982 78.437  93.713  1.00 20.26  ? 443  TYR   C CA    1 
ATOM   2327 C C     . TYR   A 1 443  ? 153.043 77.135  92.927  1.00 25.13  ? 443  TYR   C C     1 
ATOM   2328 O O     . TYR   A 1 443  ? 152.005 76.596  92.540  1.00 31.29  ? 443  TYR   C O     1 
ATOM   2329 C CB    . TYR   A 1 443  ? 153.210 79.635  92.792  1.00 19.73  ? 443  TYR   C CB    1 
ATOM   2330 C CG    . TYR   A 1 443  ? 152.556 80.895  93.299  1.00 16.83  ? 443  TYR   C CG    1 
ATOM   2331 C CD1   . TYR   A 1 443  ? 152.984 81.473  94.478  1.00 17.41  ? 443  TYR   C CD1   1 
ATOM   2332 C CD2   . TYR   A 1 443  ? 151.529 81.470  92.588  1.00 18.63  ? 443  TYR   C CD2   1 
ATOM   2333 C CE1   . TYR   A 1 443  ? 152.385 82.608  94.946  1.00 15.62  ? 443  TYR   C CE1   1 
ATOM   2334 C CE2   . TYR   A 1 443  ? 150.929 82.612  93.057  1.00 18.47  ? 443  TYR   C CE2   1 
ATOM   2335 C CZ    . TYR   A 1 443  ? 151.355 83.177  94.236  1.00 16.26  ? 443  TYR   C CZ    1 
ATOM   2336 O OH    . TYR   A 1 443  ? 150.755 84.314  94.715  1.00 17.46  ? 443  TYR   C OH    1 
ATOM   2337 N N     . VAL   A 1 444  ? 154.246 76.611  92.714  1.00 25.97  ? 444  VAL   C N     1 
ATOM   2338 C CA    . VAL   A 1 444  ? 154.385 75.353  91.996  1.00 27.75  ? 444  VAL   C CA    1 
ATOM   2339 C C     . VAL   A 1 444  ? 153.761 74.214  92.781  1.00 34.53  ? 444  VAL   C C     1 
ATOM   2340 O O     . VAL   A 1 444  ? 153.068 73.375  92.213  1.00 40.82  ? 444  VAL   C O     1 
ATOM   2341 C CB    . VAL   A 1 444  ? 155.859 75.021  91.714  1.00 30.95  ? 444  VAL   C CB    1 
ATOM   2342 C CG1   . VAL   A 1 444  ? 155.977 73.603  91.174  1.00 36.45  ? 444  VAL   C CG1   1 
ATOM   2343 C CG2   . VAL   A 1 444  ? 156.420 75.998  90.698  1.00 34.53  ? 444  VAL   C CG2   1 
ATOM   2344 N N     . PHE   A 1 445  ? 154.015 74.180  94.086  1.00 36.27  ? 445  PHE   C N     1 
ATOM   2345 C CA    . PHE   A 1 445  ? 153.476 73.133  94.944  1.00 37.67  ? 445  PHE   C CA    1 
ATOM   2346 C C     . PHE   A 1 445  ? 151.956 73.099  94.858  1.00 38.96  ? 445  PHE   C C     1 
ATOM   2347 O O     . PHE   A 1 445  ? 151.355 72.037  94.677  1.00 45.11  ? 445  PHE   C O     1 
ATOM   2348 C CB    . PHE   A 1 445  ? 153.914 73.371  96.388  1.00 42.25  ? 445  PHE   C CB    1 
ATOM   2349 C CG    . PHE   A 1 445  ? 153.464 72.328  97.361  1.00 45.33  ? 445  PHE   C CG    1 
ATOM   2350 C CD1   . PHE   A 1 445  ? 154.167 71.141  97.482  1.00 49.46  ? 445  PHE   C CD1   1 
ATOM   2351 C CD2   . PHE   A 1 445  ? 152.352 72.529  98.165  1.00 46.11  ? 445  PHE   C CD2   1 
ATOM   2352 C CE1   . PHE   A 1 445  ? 153.772 70.179  98.382  1.00 49.97  ? 445  PHE   C CE1   1 
ATOM   2353 C CE2   . PHE   A 1 445  ? 151.956 71.563  99.066  1.00 49.37  ? 445  PHE   C CE2   1 
ATOM   2354 C CZ    . PHE   A 1 445  ? 152.673 70.389  99.171  1.00 51.76  ? 445  PHE   C CZ    1 
ATOM   2355 N N     . PHE   A 1 446  ? 151.338 74.269  94.970  1.00 36.57  ? 446  PHE   C N     1 
ATOM   2356 C CA    . PHE   A 1 446  ? 149.890 74.391  94.892  1.00 35.48  ? 446  PHE   C CA    1 
ATOM   2357 C C     . PHE   A 1 446  ? 149.354 73.841  93.581  1.00 41.36  ? 446  PHE   C C     1 
ATOM   2358 O O     . PHE   A 1 446  ? 148.436 73.018  93.572  1.00 48.68  ? 446  PHE   C O     1 
ATOM   2359 C CB    . PHE   A 1 446  ? 149.505 75.860  95.028  1.00 32.39  ? 446  PHE   C CB    1 
ATOM   2360 C CG    . PHE   A 1 446  ? 148.047 76.170  94.860  1.00 29.55  ? 446  PHE   C CG    1 
ATOM   2361 C CD1   . PHE   A 1 446  ? 147.154 75.996  95.897  1.00 28.82  ? 446  PHE   C CD1   1 
ATOM   2362 C CD2   . PHE   A 1 446  ? 147.573 76.657  93.659  1.00 33.54  ? 446  PHE   C CD2   1 
ATOM   2363 C CE1   . PHE   A 1 446  ? 145.823 76.307  95.732  1.00 32.24  ? 446  PHE   C CE1   1 
ATOM   2364 C CE2   . PHE   A 1 446  ? 146.245 76.967  93.493  1.00 36.27  ? 446  PHE   C CE2   1 
ATOM   2365 C CZ    . PHE   A 1 446  ? 145.369 76.794  94.529  1.00 30.71  ? 446  PHE   C CZ    1 
ATOM   2366 N N     . LEU   A 1 447  ? 149.931 74.294  92.470  1.00 38.74  ? 447  LEU   C N     1 
ATOM   2367 C CA    . LEU   A 1 447  ? 149.462 73.878  91.158  1.00 42.65  ? 447  LEU   C CA    1 
ATOM   2368 C C     . LEU   A 1 447  ? 149.814 72.432  90.862  1.00 50.92  ? 447  LEU   C C     1 
ATOM   2369 O O     . LEU   A 1 447  ? 149.091 71.749  90.140  1.00 60.72  ? 447  LEU   C O     1 
ATOM   2370 C CB    . LEU   A 1 447  ? 150.040 74.788  90.081  1.00 35.06  ? 447  LEU   C CB    1 
ATOM   2371 C CG    . LEU   A 1 447  ? 149.545 76.236  90.098  1.00 33.83  ? 447  LEU   C CG    1 
ATOM   2372 C CD1   . LEU   A 1 447  ? 150.363 77.027  89.130  1.00 34.51  ? 447  LEU   C CD1   1 
ATOM   2373 C CD2   . LEU   A 1 447  ? 148.068 76.294  89.733  1.00 42.99  ? 447  LEU   C CD2   1 
ATOM   2374 N N     . SER   A 1 448  ? 150.914 71.952  91.421  1.00 45.24  ? 448  SER   C N     1 
ATOM   2375 C CA    . SER   A 1 448  ? 151.299 70.564  91.227  1.00 49.74  ? 448  SER   C CA    1 
ATOM   2376 C C     . SER   A 1 448  ? 150.219 69.637  91.761  1.00 56.81  ? 448  SER   C C     1 
ATOM   2377 O O     . SER   A 1 448  ? 149.755 68.739  91.057  1.00 67.12  ? 448  SER   C O     1 
ATOM   2378 C CB    . SER   A 1 448  ? 152.612 70.289  91.929  1.00 50.79  ? 448  SER   C CB    1 
ATOM   2379 O OG    . SER   A 1 448  ? 152.944 68.936  91.854  1.00 61.62  ? 448  SER   C OG    1 
ATOM   2380 N N     . SER   A 1 449  ? 149.779 69.893  92.992  1.00 51.79  ? 449  SER   C N     1 
ATOM   2381 C CA    . SER   A 1 449  ? 148.727 69.090  93.601  1.00 57.48  ? 449  SER   C CA    1 
ATOM   2382 C C     . SER   A 1 449  ? 147.383 69.311  92.911  1.00 62.76  ? 449  SER   C C     1 
ATOM   2383 O O     . SER   A 1 449  ? 146.583 68.388  92.788  1.00 71.87  ? 449  SER   C O     1 
ATOM   2384 C CB    . SER   A 1 449  ? 148.598 69.416  95.078  1.00 54.74  ? 449  SER   C CB    1 
ATOM   2385 O OG    . SER   A 1 449  ? 149.726 68.988  95.793  1.00 56.06  ? 449  SER   C OG    1 
ATOM   2386 N N     . LEU   A 1 450  ? 147.138 70.542  92.475  1.00 58.41  ? 450  LEU   C N     1 
ATOM   2387 C CA    . LEU   A 1 450  ? 145.877 70.901  91.840  1.00 59.31  ? 450  LEU   C CA    1 
ATOM   2388 C C     . LEU   A 1 450  ? 145.699 70.297  90.447  1.00 65.50  ? 450  LEU   C C     1 
ATOM   2389 O O     . LEU   A 1 450  ? 144.625 69.790  90.115  1.00 88.52  ? 450  LEU   C O     1 
ATOM   2390 C CB    . LEU   A 1 450  ? 145.779 72.432  91.755  1.00 67.01  ? 450  LEU   C CB    1 
ATOM   2391 C CG    . LEU   A 1 450  ? 144.434 73.009  91.345  1.00 65.87  ? 450  LEU   C CG    1 
ATOM   2392 C CD1   . LEU   A 1 450  ? 144.214 74.320  92.084  1.00 53.45  ? 450  LEU   C CD1   1 
ATOM   2393 C CD2   . LEU   A 1 450  ? 144.408 73.258  89.853  1.00 69.93  ? 450  LEU   C CD2   1 
ATOM   2394 N N     . LEU   A 1 451  ? 146.733 70.388  89.613  1.00 60.94  ? 451  LEU   C N     1 
ATOM   2395 C CA    . LEU   A 1 451  ? 146.643 69.985  88.210  1.00 63.06  ? 451  LEU   C CA    1 
ATOM   2396 C C     . LEU   A 1 451  ? 147.025 68.528  87.932  1.00 71.38  ? 451  LEU   C C     1 
ATOM   2397 O O     . LEU   A 1 451  ? 146.676 67.984  86.886  1.00 80.92  ? 451  LEU   C O     1 
ATOM   2398 C CB    . LEU   A 1 451  ? 147.521 70.906  87.349  1.00 77.33  ? 451  LEU   C CB    1 
ATOM   2399 C CG    . LEU   A 1 451  ? 147.119 72.402  87.288  1.00 68.58  ? 451  LEU   C CG    1 
ATOM   2400 C CD1   . LEU   A 1 451  ? 148.204 73.179  86.550  1.00 56.55  ? 451  LEU   C CD1   1 
ATOM   2401 C CD2   . LEU   A 1 451  ? 145.781 72.550  86.557  1.00 63.71  ? 451  LEU   C CD2   1 
ATOM   2402 N N     . GLN   A 1 452  ? 147.777 67.899  88.831  1.00 64.77  ? 452  GLN   C N     1 
ATOM   2403 C CA    . GLN   A 1 452  ? 148.193 66.526  88.577  1.00 76.49  ? 452  GLN   C CA    1 
ATOM   2404 C C     . GLN   A 1 452  ? 147.045 65.488  88.571  1.00 81.93  ? 452  GLN   C C     1 
ATOM   2405 O O     . GLN   A 1 452  ? 147.002 64.651  87.669  1.00 81.89  ? 452  GLN   C O     1 
ATOM   2406 C CB    . GLN   A 1 452  ? 149.296 66.100  89.557  1.00 82.30  ? 452  GLN   C CB    1 
ATOM   2407 C CG    . GLN   A 1 452  ? 149.821 64.692  89.329  1.00 85.90  ? 452  GLN   C CG    1 
ATOM   2408 C CD    . GLN   A 1 452  ? 150.447 64.522  87.959  1.00 83.99  ? 452  GLN   C CD    1 
ATOM   2409 O OE1   . GLN   A 1 452  ? 151.024 65.464  87.406  1.00 84.58  ? 452  GLN   C OE1   1 
ATOM   2410 N NE2   . GLN   A 1 452  ? 150.337 63.321  87.404  1.00 84.53  ? 452  GLN   C NE2   1 
ATOM   2411 N N     . PRO   A 1 453  ? 146.107 65.508  89.537  1.00 80.59  ? 453  PRO   C N     1 
ATOM   2412 C CA    . PRO   A 1 453  ? 145.054 64.520  89.711  1.00 83.12  ? 453  PRO   C CA    1 
ATOM   2413 C C     . PRO   A 1 453  ? 144.339 64.198  88.410  1.00 82.21  ? 453  PRO   C C     1 
ATOM   2414 O O     . PRO   A 1 453  ? 143.134 63.943  88.411  1.00 86.46  ? 453  PRO   C O     1 
ATOM   2415 C CB    . PRO   A 1 453  ? 144.121 65.212  90.710  1.00 78.24  ? 453  PRO   C CB    1 
ATOM   2416 C CG    . PRO   A 1 453  ? 145.045 66.073  91.523  1.00 74.96  ? 453  PRO   C CG    1 
ATOM   2417 C CD    . PRO   A 1 453  ? 146.046 66.604  90.514  1.00 71.83  ? 453  PRO   C CD    1 
ATOM   2418 N N     . LEU   A 1 462  ? 143.163 69.496  83.459  1.00 78.79  ? 462  LEU   C N     1 
ATOM   2419 C CA    . LEU   A 1 462  ? 144.368 69.179  84.220  1.00 82.75  ? 462  LEU   C CA    1 
ATOM   2420 C C     . LEU   A 1 462  ? 145.625 69.594  83.462  1.00 86.71  ? 462  LEU   C C     1 
ATOM   2421 O O     . LEU   A 1 462  ? 145.581 70.480  82.608  1.00 76.80  ? 462  LEU   C O     1 
ATOM   2422 C CB    . LEU   A 1 462  ? 144.413 67.673  84.521  1.00 83.62  ? 462  LEU   C CB    1 
ATOM   2423 C CG    . LEU   A 1 462  ? 143.245 67.097  85.336  1.00 79.23  ? 462  LEU   C CG    1 
ATOM   2424 C CD1   . LEU   A 1 462  ? 143.419 65.598  85.424  1.00 80.90  ? 462  LEU   C CD1   1 
ATOM   2425 C CD2   . LEU   A 1 462  ? 143.224 67.718  86.739  1.00 78.65  ? 462  LEU   C CD2   1 
ATOM   2426 N N     . CYS   A 1 463  ? 146.741 68.928  83.761  1.00 77.28  ? 463  CYS   C N     1 
ATOM   2427 C CA    . CYS   A 1 463  ? 148.031 69.243  83.142  1.00 85.19  ? 463  CYS   C CA    1 
ATOM   2428 C C     . CYS   A 1 463  ? 148.025 69.071  81.623  1.00 78.65  ? 463  CYS   C C     1 
ATOM   2429 O O     . CYS   A 1 463  ? 148.857 69.648  80.921  1.00 84.37  ? 463  CYS   C O     1 
ATOM   2430 C CB    . CYS   A 1 463  ? 149.137 68.361  83.722  1.00 81.36  ? 463  CYS   C CB    1 
ATOM   2431 S SG    . CYS   A 1 463  ? 149.536 68.688  85.458  1.00 87.27  ? 463  CYS   C SG    1 
ATOM   2432 N N     . ALA   A 1 464  ? 147.075 68.296  81.115  1.00 85.72  ? 464  ALA   C N     1 
ATOM   2433 C CA    . ALA   A 1 464  ? 146.952 68.044  79.683  1.00 84.62  ? 464  ALA   C CA    1 
ATOM   2434 C C     . ALA   A 1 464  ? 146.708 69.339  78.917  1.00 77.62  ? 464  ALA   C C     1 
ATOM   2435 O O     . ALA   A 1 464  ? 146.967 69.419  77.715  1.00 79.66  ? 464  ALA   C O     1 
ATOM   2436 C CB    . ALA   A 1 464  ? 145.818 67.070  79.416  1.00 84.61  ? 464  ALA   C CB    1 
ATOM   2437 N N     . HIS   A 1 465  ? 146.182 70.343  79.609  1.00 82.56  ? 465  HIS   C N     1 
ATOM   2438 C CA    . HIS   A 1 465  ? 145.852 71.613  78.991  1.00 72.86  ? 465  HIS   C CA    1 
ATOM   2439 C C     . HIS   A 1 465  ? 146.751 72.731  79.501  1.00 68.18  ? 465  HIS   C C     1 
ATOM   2440 O O     . HIS   A 1 465  ? 146.419 73.911  79.368  1.00 69.46  ? 465  HIS   C O     1 
ATOM   2441 C CB    . HIS   A 1 465  ? 144.387 71.949  79.261  1.00 81.96  ? 465  HIS   C CB    1 
ATOM   2442 C CG    . HIS   A 1 465  ? 143.454 70.952  78.671  1.00 83.71  ? 465  HIS   C CG    1 
ATOM   2443 N ND1   . HIS   A 1 465  ? 143.116 70.947  77.335  1.00 83.80  ? 465  HIS   C ND1   1 
ATOM   2444 C CD2   . HIS   A 1 465  ? 142.799 69.912  79.232  1.00 85.23  ? 465  HIS   C CD2   1 
ATOM   2445 C CE1   . HIS   A 1 465  ? 142.286 69.947  77.102  1.00 91.51  ? 465  HIS   C CE1   1 
ATOM   2446 N NE2   . HIS   A 1 465  ? 142.079 69.302  78.237  1.00 90.05  ? 465  HIS   C NE2   1 
ATOM   2447 N N     . LEU   A 1 466  ? 147.896 72.363  80.074  1.00 68.86  ? 466  LEU   C N     1 
ATOM   2448 C CA    . LEU   A 1 466  ? 148.823 73.344  80.622  1.00 61.63  ? 466  LEU   C CA    1 
ATOM   2449 C C     . LEU   A 1 466  ? 149.249 74.355  79.577  1.00 58.40  ? 466  LEU   C C     1 
ATOM   2450 O O     . LEU   A 1 466  ? 149.358 75.546  79.870  1.00 57.28  ? 466  LEU   C O     1 
ATOM   2451 C CB    . LEU   A 1 466  ? 150.074 72.651  81.178  1.00 64.29  ? 466  LEU   C CB    1 
ATOM   2452 C CG    . LEU   A 1 466  ? 151.186 73.572  81.757  1.00 57.06  ? 466  LEU   C CG    1 
ATOM   2453 C CD1   . LEU   A 1 466  ? 150.652 74.359  82.960  1.00 55.74  ? 466  LEU   C CD1   1 
ATOM   2454 C CD2   . LEU   A 1 466  ? 152.373 72.710  82.153  1.00 67.36  ? 466  LEU   C CD2   1 
ATOM   2455 N N     . TRP   A 1 467  ? 149.519 73.886  78.364  1.00 59.21  ? 467  TRP   C N     1 
ATOM   2456 C CA    . TRP   A 1 467  ? 149.962 74.786  77.314  1.00 59.39  ? 467  TRP   C CA    1 
ATOM   2457 C C     . TRP   A 1 467  ? 148.878 75.803  76.991  1.00 56.00  ? 467  TRP   C C     1 
ATOM   2458 O O     . TRP   A 1 467  ? 149.140 77.001  76.912  1.00 57.89  ? 467  TRP   C O     1 
ATOM   2459 C CB    . TRP   A 1 467  ? 150.340 74.009  76.056  1.00 60.83  ? 467  TRP   C CB    1 
ATOM   2460 C CG    . TRP   A 1 467  ? 150.956 74.868  75.007  1.00 65.49  ? 467  TRP   C CG    1 
ATOM   2461 C CD1   . TRP   A 1 467  ? 152.280 75.156  74.876  1.00 64.62  ? 467  TRP   C CD1   1 
ATOM   2462 C CD2   . TRP   A 1 467  ? 150.286 75.569  73.937  1.00 68.58  ? 467  TRP   C CD2   1 
ATOM   2463 N NE1   . TRP   A 1 467  ? 152.480 75.982  73.805  1.00 66.97  ? 467  TRP   C NE1   1 
ATOM   2464 C CE2   . TRP   A 1 467  ? 151.271 76.242  73.214  1.00 69.33  ? 467  TRP   C CE2   1 
ATOM   2465 C CE3   . TRP   A 1 467  ? 148.948 75.670  73.532  1.00 69.20  ? 467  TRP   C CE3   1 
ATOM   2466 C CZ2   . TRP   A 1 467  ? 150.965 77.023  72.114  1.00 73.28  ? 467  TRP   C CZ2   1 
ATOM   2467 C CZ3   . TRP   A 1 467  ? 148.643 76.450  72.428  1.00 71.31  ? 467  TRP   C CZ3   1 
ATOM   2468 C CH2   . TRP   A 1 467  ? 149.625 77.104  71.734  1.00 74.69  ? 467  TRP   C CH2   1 
ATOM   2469 N N     . GLY   A 1 468  ? 147.649 75.323  76.809  1.00 57.80  ? 468  GLY   C N     1 
ATOM   2470 C CA    . GLY   A 1 468  ? 146.543 76.209  76.469  1.00 58.83  ? 468  GLY   C CA    1 
ATOM   2471 C C     . GLY   A 1 468  ? 146.292 77.227  77.572  1.00 54.90  ? 468  GLY   C C     1 
ATOM   2472 O O     . GLY   A 1 468  ? 146.042 78.403  77.300  1.00 56.00  ? 468  GLY   C O     1 
ATOM   2473 N N     . LEU   A 1 469  ? 146.382 76.780  78.822  1.00 51.95  ? 469  LEU   C N     1 
ATOM   2474 C CA    . LEU   A 1 469  ? 146.157 77.656  79.962  1.00 49.14  ? 469  LEU   C CA    1 
ATOM   2475 C C     . LEU   A 1 469  ? 147.253 78.711  80.055  1.00 48.67  ? 469  LEU   C C     1 
ATOM   2476 O O     . LEU   A 1 469  ? 146.976 79.885  80.313  1.00 47.14  ? 469  LEU   C O     1 
ATOM   2477 C CB    . LEU   A 1 469  ? 146.095 76.829  81.257  1.00 47.19  ? 469  LEU   C CB    1 
ATOM   2478 C CG    . LEU   A 1 469  ? 145.802 77.593  82.574  1.00 38.80  ? 469  LEU   C CG    1 
ATOM   2479 C CD1   . LEU   A 1 469  ? 144.444 78.290  82.485  1.00 44.90  ? 469  LEU   C CD1   1 
ATOM   2480 C CD2   . LEU   A 1 469  ? 145.820 76.600  83.735  1.00 42.76  ? 469  LEU   C CD2   1 
ATOM   2481 N N     . CYS   A 1 470  ? 148.497 78.298  79.826  1.00 47.22  ? 470  CYS   C N     1 
ATOM   2482 C CA    . CYS   A 1 470  ? 149.614 79.229  79.868  1.00 43.06  ? 470  CYS   C CA    1 
ATOM   2483 C C     . CYS   A 1 470  ? 149.521 80.252  78.743  1.00 46.76  ? 470  CYS   C C     1 
ATOM   2484 O O     . CYS   A 1 470  ? 149.800 81.433  78.952  1.00 46.63  ? 470  CYS   C O     1 
ATOM   2485 C CB    . CYS   A 1 470  ? 150.939 78.485  79.777  1.00 43.80  ? 470  CYS   C CB    1 
ATOM   2486 S SG    . CYS   A 1 470  ? 151.315 77.488  81.235  1.00 49.22  ? 470  CYS   C SG    1 
ATOM   2487 N N     . SER   A 1 471  ? 149.105 79.809  77.556  1.00 47.82  ? 471  SER   C N     1 
ATOM   2488 C CA    . SER   A 1 471  ? 148.948 80.717  76.427  1.00 47.38  ? 471  SER   C CA    1 
ATOM   2489 C C     . SER   A 1 471  ? 147.864 81.744  76.716  1.00 46.12  ? 471  SER   C C     1 
ATOM   2490 O O     . SER   A 1 471  ? 148.016 82.924  76.393  1.00 46.35  ? 471  SER   C O     1 
ATOM   2491 C CB    . SER   A 1 471  ? 148.603 79.948  75.166  1.00 55.47  ? 471  SER   C CB    1 
ATOM   2492 O OG    . SER   A 1 471  ? 149.668 79.142  74.751  1.00 56.41  ? 471  SER   C OG    1 
ATOM   2493 N N     . LEU   A 1 472  ? 146.783 81.304  77.357  1.00 49.38  ? 472  LEU   C N     1 
ATOM   2494 C CA    . LEU   A 1 472  ? 145.699 82.200  77.726  1.00 47.48  ? 472  LEU   C CA    1 
ATOM   2495 C C     . LEU   A 1 472  ? 146.210 83.301  78.650  1.00 46.01  ? 472  LEU   C C     1 
ATOM   2496 O O     . LEU   A 1 472  ? 145.931 84.481  78.451  1.00 46.97  ? 472  LEU   C O     1 
ATOM   2497 C CB    . LEU   A 1 472  ? 144.593 81.424  78.452  1.00 49.17  ? 472  LEU   C CB    1 
ATOM   2498 C CG    . LEU   A 1 472  ? 143.377 82.239  78.924  1.00 49.25  ? 472  LEU   C CG    1 
ATOM   2499 C CD1   . LEU   A 1 472  ? 142.583 82.711  77.711  1.00 53.79  ? 472  LEU   C CD1   1 
ATOM   2500 C CD2   . LEU   A 1 472  ? 142.529 81.394  79.854  1.00 48.48  ? 472  LEU   C CD2   1 
ATOM   2501 N N     . ALA   A 1 473  ? 146.959 82.888  79.676  1.00 42.54  ? 473  ALA   C N     1 
ATOM   2502 C CA    . ALA   A 1 473  ? 147.491 83.848  80.639  1.00 36.24  ? 473  ALA   C CA    1 
ATOM   2503 C C     . ALA   A 1 473  ? 148.483 84.787  79.976  1.00 36.90  ? 473  ALA   C C     1 
ATOM   2504 O O     . ALA   A 1 473  ? 148.467 86.001  80.252  1.00 37.37  ? 473  ALA   C O     1 
ATOM   2505 C CB    . ALA   A 1 473  ? 148.176 83.097  81.770  1.00 35.11  ? 473  ALA   C CB    1 
ATOM   2506 N N     . ALA   A 1 474  ? 149.332 84.271  79.102  1.00 40.25  ? 474  ALA   C N     1 
ATOM   2507 C CA    . ALA   A 1 474  ? 150.328 85.069  78.419  1.00 38.76  ? 474  ALA   C CA    1 
ATOM   2508 C C     . ALA   A 1 474  ? 149.670 86.126  77.542  1.00 41.03  ? 474  ALA   C C     1 
ATOM   2509 O O     . ALA   A 1 474  ? 150.090 87.275  77.505  1.00 42.54  ? 474  ALA   C O     1 
ATOM   2510 C CB    . ALA   A 1 474  ? 151.251 84.198  77.594  1.00 41.19  ? 474  ALA   C CB    1 
ATOM   2511 N N     . ASP   A 1 475  ? 148.595 85.718  76.862  1.00 42.24  ? 475  ASP   C N     1 
ATOM   2512 C CA    . ASP   A 1 475  ? 147.864 86.644  76.009  1.00 41.72  ? 475  ASP   C CA    1 
ATOM   2513 C C     . ASP   A 1 475  ? 147.246 87.743  76.848  1.00 39.68  ? 475  ASP   C C     1 
ATOM   2514 O O     . ASP   A 1 475  ? 147.293 88.919  76.481  1.00 40.32  ? 475  ASP   C O     1 
ATOM   2515 C CB    . ASP   A 1 475  ? 146.769 85.900  75.239  1.00 43.37  ? 475  ASP   C CB    1 
ATOM   2516 C CG    . ASP   A 1 475  ? 146.010 86.785  74.272  1.00 46.67  ? 475  ASP   C CG    1 
ATOM   2517 O OD1   . ASP   A 1 475  ? 146.601 87.253  73.332  1.00 47.76  ? 475  ASP   C OD1   1 
ATOM   2518 O OD2   . ASP   A 1 475  ? 144.839 86.988  74.483  1.00 49.31  ? 475  ASP   C OD2   1 
ATOM   2519 N N     . GLY   A 1 476  ? 146.696 87.368  77.997  1.00 40.69  ? 476  GLY   C N     1 
ATOM   2520 C CA    . GLY   A 1 476  ? 146.069 88.326  78.895  1.00 39.48  ? 476  GLY   C CA    1 
ATOM   2521 C C     . GLY   A 1 476  ? 147.044 89.403  79.361  1.00 38.09  ? 476  GLY   C C     1 
ATOM   2522 O O     . GLY   A 1 476  ? 146.661 90.561  79.533  1.00 39.70  ? 476  GLY   C O     1 
ATOM   2523 N N     . ILE   A 1 477  ? 148.308 89.041  79.555  1.00 38.02  ? 477  ILE   C N     1 
ATOM   2524 C CA    . ILE   A 1 477  ? 149.284 90.031  79.991  1.00 36.26  ? 477  ILE   C CA    1 
ATOM   2525 C C     . ILE   A 1 477  ? 149.654 90.988  78.864  1.00 37.40  ? 477  ILE   C C     1 
ATOM   2526 O O     . ILE   A 1 477  ? 149.662 92.208  79.050  1.00 37.80  ? 477  ILE   C O     1 
ATOM   2527 C CB    . ILE   A 1 477  ? 150.569 89.356  80.520  1.00 33.23  ? 477  ILE   C CB    1 
ATOM   2528 C CG1   . ILE   A 1 477  ? 150.272 88.483  81.775  1.00 32.95  ? 477  ILE   C CG1   1 
ATOM   2529 C CG2   . ILE   A 1 477  ? 151.630 90.406  80.826  1.00 30.70  ? 477  ILE   C CG2   1 
ATOM   2530 C CD1   . ILE   A 1 477  ? 149.716 89.227  82.985  1.00 32.05  ? 477  ILE   C CD1   1 
ATOM   2531 N N     . TRP   A 1 478  ? 149.960 90.436  77.693  1.00 39.92  ? 478  TRP   C N     1 
ATOM   2532 C CA    . TRP   A 1 478  ? 150.415 91.251  76.571  1.00 41.71  ? 478  TRP   C CA    1 
ATOM   2533 C C     . TRP   A 1 478  ? 149.312 92.094  75.935  1.00 42.12  ? 478  TRP   C C     1 
ATOM   2534 O O     . TRP   A 1 478  ? 149.567 93.210  75.482  1.00 40.05  ? 478  TRP   C O     1 
ATOM   2535 C CB    . TRP   A 1 478  ? 151.061 90.363  75.507  1.00 43.41  ? 478  TRP   C CB    1 
ATOM   2536 C CG    . TRP   A 1 478  ? 152.456 89.947  75.859  1.00 45.73  ? 478  TRP   C CG    1 
ATOM   2537 C CD1   . TRP   A 1 478  ? 152.875 88.706  76.229  1.00 46.31  ? 478  TRP   C CD1   1 
ATOM   2538 C CD2   . TRP   A 1 478  ? 153.635 90.784  75.871  1.00 47.59  ? 478  TRP   C CD2   1 
ATOM   2539 N NE1   . TRP   A 1 478  ? 154.224 88.716  76.470  1.00 48.87  ? 478  TRP   C NE1   1 
ATOM   2540 C CE2   . TRP   A 1 478  ? 154.702 89.980  76.259  1.00 49.49  ? 478  TRP   C CE2   1 
ATOM   2541 C CE3   . TRP   A 1 478  ? 153.864 92.133  75.594  1.00 43.49  ? 478  TRP   C CE3   1 
ATOM   2542 C CZ2   . TRP   A 1 478  ? 155.984 90.475  76.375  1.00 47.41  ? 478  TRP   C CZ2   1 
ATOM   2543 C CZ3   . TRP   A 1 478  ? 155.155 92.628  75.714  1.00 42.75  ? 478  TRP   C CZ3   1 
ATOM   2544 C CH2   . TRP   A 1 478  ? 156.183 91.822  76.095  1.00 44.92  ? 478  TRP   C CH2   1 
ATOM   2545 N N     . ASN   A 1 479  ? 148.087 91.572  75.906  1.00 41.29  ? 479  ASN   C N     1 
ATOM   2546 C CA    . ASN   A 1 479  ? 146.974 92.293  75.294  1.00 37.46  ? 479  ASN   C CA    1 
ATOM   2547 C C     . ASN   A 1 479  ? 146.062 92.940  76.330  1.00 38.05  ? 479  ASN   C C     1 
ATOM   2548 O O     . ASN   A 1 479  ? 144.972 93.409  76.002  1.00 39.52  ? 479  ASN   C O     1 
ATOM   2549 C CB    . ASN   A 1 479  ? 146.200 91.382  74.360  1.00 38.17  ? 479  ASN   C CB    1 
ATOM   2550 C CG    . ASN   A 1 479  ? 146.975 91.097  73.091  1.00 41.73  ? 479  ASN   C CG    1 
ATOM   2551 O OD1   . ASN   A 1 479  ? 147.576 92.014  72.518  1.00 42.68  ? 479  ASN   C OD1   1 
ATOM   2552 N ND2   . ASN   A 1 479  ? 146.978 89.867  72.640  1.00 43.22  ? 479  ASN   C ND2   1 
ATOM   2553 N N     . GLN   A 1 480  ? 146.532 92.995  77.571  1.00 38.36  ? 480  GLN   C N     1 
ATOM   2554 C CA    . GLN   A 1 480  ? 145.826 93.665  78.658  1.00 36.29  ? 480  GLN   C CA    1 
ATOM   2555 C C     . GLN   A 1 480  ? 144.380 93.212  78.847  1.00 36.07  ? 480  GLN   C C     1 
ATOM   2556 O O     . GLN   A 1 480  ? 143.445 94.003  78.729  1.00 35.75  ? 480  GLN   C O     1 
ATOM   2557 C CB    . GLN   A 1 480  ? 145.898 95.178  78.459  1.00 35.64  ? 480  GLN   C CB    1 
ATOM   2558 C CG    . GLN   A 1 480  ? 147.291 95.728  78.660  1.00 36.17  ? 480  GLN   C CG    1 
ATOM   2559 C CD    . GLN   A 1 480  ? 147.664 95.734  80.124  1.00 36.85  ? 480  GLN   C CD    1 
ATOM   2560 O OE1   . GLN   A 1 480  ? 147.186 96.595  80.877  1.00 37.07  ? 480  GLN   C OE1   1 
ATOM   2561 N NE2   . GLN   A 1 480  ? 148.494 94.775  80.548  1.00 35.48  ? 480  GLN   C NE2   1 
ATOM   2562 N N     . LYS   A 1 481  ? 144.211 91.924  79.133  1.00 36.89  ? 481  LYS   C N     1 
ATOM   2563 C CA    . LYS   A 1 481  ? 142.897 91.346  79.391  1.00 36.37  ? 481  LYS   C CA    1 
ATOM   2564 C C     . LYS   A 1 481  ? 142.907 90.474  80.645  1.00 38.89  ? 481  LYS   C C     1 
ATOM   2565 O O     . LYS   A 1 481  ? 143.596 89.457  80.701  1.00 39.93  ? 481  LYS   C O     1 
ATOM   2566 C CB    . LYS   A 1 481  ? 142.437 90.518  78.189  1.00 40.10  ? 481  LYS   C CB    1 
ATOM   2567 C CG    . LYS   A 1 481  ? 141.063 89.866  78.360  1.00 46.10  ? 481  LYS   C CG    1 
ATOM   2568 C CD    . LYS   A 1 481  ? 140.710 88.957  77.181  1.00 53.82  ? 481  LYS   C CD    1 
ATOM   2569 C CE    . LYS   A 1 481  ? 140.351 89.749  75.932  1.00 57.82  ? 481  LYS   C CE    1 
ATOM   2570 N NZ    . LYS   A 1 481  ? 139.802 88.870  74.869  1.00 64.67  ? 481  LYS   C NZ    1 
ATOM   2571 N N     . ILE   A 1 482  ? 142.105 90.857  81.637  1.00 37.89  ? 482  ILE   C N     1 
ATOM   2572 C CA    . ILE   A 1 482  ? 141.968 90.065  82.859  1.00 34.84  ? 482  ILE   C CA    1 
ATOM   2573 C C     . ILE   A 1 482  ? 140.704 89.219  82.818  1.00 41.93  ? 482  ILE   C C     1 
ATOM   2574 O O     . ILE   A 1 482  ? 140.687 88.090  83.309  1.00 45.83  ? 482  ILE   C O     1 
ATOM   2575 C CB    . ILE   A 1 482  ? 141.962 90.940  84.127  1.00 32.39  ? 482  ILE   C CB    1 
ATOM   2576 C CG1   . ILE   A 1 482  ? 143.314 91.636  84.282  1.00 36.29  ? 482  ILE   C CG1   1 
ATOM   2577 C CG2   . ILE   A 1 482  ? 141.668 90.069  85.357  1.00 36.36  ? 482  ILE   C CG2   1 
ATOM   2578 C CD1   . ILE   A 1 482  ? 143.341 92.699  85.368  1.00 34.02  ? 482  ILE   C CD1   1 
ATOM   2579 N N     . LEU   A 1 483  ? 139.632 89.794  82.282  1.00 42.89  ? 483  LEU   C N     1 
ATOM   2580 C CA    . LEU   A 1 483  ? 138.344 89.120  82.223  1.00 43.39  ? 483  LEU   C CA    1 
ATOM   2581 C C     . LEU   A 1 483  ? 138.143 88.479  80.857  1.00 46.80  ? 483  LEU   C C     1 
ATOM   2582 O O     . LEU   A 1 483  ? 138.112 89.168  79.837  1.00 47.74  ? 483  LEU   C O     1 
ATOM   2583 C CB    . LEU   A 1 483  ? 137.219 90.121  82.510  1.00 41.83  ? 483  LEU   C CB    1 
ATOM   2584 C CG    . LEU   A 1 483  ? 137.325 90.880  83.839  1.00 39.64  ? 483  LEU   C CG    1 
ATOM   2585 C CD1   . LEU   A 1 483  ? 136.155 91.833  83.963  1.00 41.43  ? 483  LEU   C CD1   1 
ATOM   2586 C CD2   . LEU   A 1 483  ? 137.340 89.892  84.994  1.00 45.19  ? 483  LEU   C CD2   1 
ATOM   2587 N N     . PHE   A 1 484  ? 138.039 87.155  80.847  1.00 48.73  ? 484  PHE   C N     1 
ATOM   2588 C CA    . PHE   A 1 484  ? 137.965 86.392  79.608  1.00 52.01  ? 484  PHE   C CA    1 
ATOM   2589 C C     . PHE   A 1 484  ? 136.536 86.031  79.247  1.00 55.96  ? 484  PHE   C C     1 
ATOM   2590 O O     . PHE   A 1 484  ? 135.746 85.633  80.103  1.00 60.58  ? 484  PHE   C O     1 
ATOM   2591 C CB    . PHE   A 1 484  ? 138.768 85.098  79.741  1.00 53.23  ? 484  PHE   C CB    1 
ATOM   2592 C CG    . PHE   A 1 484  ? 140.220 85.313  79.985  1.00 52.04  ? 484  PHE   C CG    1 
ATOM   2593 C CD1   . PHE   A 1 484  ? 140.743 85.125  81.249  1.00 47.83  ? 484  PHE   C CD1   1 
ATOM   2594 C CD2   . PHE   A 1 484  ? 141.067 85.712  78.967  1.00 55.15  ? 484  PHE   C CD2   1 
ATOM   2595 C CE1   . PHE   A 1 484  ? 142.080 85.327  81.494  1.00 47.46  ? 484  PHE   C CE1   1 
ATOM   2596 C CE2   . PHE   A 1 484  ? 142.412 85.914  79.209  1.00 50.90  ? 484  PHE   C CE2   1 
ATOM   2597 C CZ    . PHE   A 1 484  ? 142.917 85.719  80.476  1.00 48.42  ? 484  PHE   C CZ    1 
ATOM   2598 N N     . GLU   A 1 485  ? 136.213 86.134  77.966  1.00 64.32  ? 485  GLU   C N     1 
ATOM   2599 C CA    . GLU   A 1 485  ? 134.907 85.717  77.478  1.00 67.14  ? 485  GLU   C CA    1 
ATOM   2600 C C     . GLU   A 1 485  ? 134.963 84.234  77.160  1.00 66.25  ? 485  GLU   C C     1 
ATOM   2601 O O     . GLU   A 1 485  ? 136.035 83.705  76.865  1.00 73.37  ? 485  GLU   C O     1 
ATOM   2602 C CB    . GLU   A 1 485  ? 134.497 86.532  76.248  1.00 72.78  ? 485  GLU   C CB    1 
ATOM   2603 C CG    . GLU   A 1 485  ? 133.033 86.377  75.839  1.00 76.62  ? 485  GLU   C CG    1 
ATOM   2604 C CD    . GLU   A 1 485  ? 132.629 87.318  74.741  1.00 80.50  ? 485  GLU   C CD    1 
ATOM   2605 O OE1   . GLU   A 1 485  ? 133.423 88.149  74.374  1.00 81.66  ? 485  GLU   C OE1   1 
ATOM   2606 O OE2   . GLU   A 1 485  ? 131.524 87.205  74.267  1.00 82.40  ? 485  GLU   C OE2   1 
ATOM   2607 N N     . GLU   A 1 486  ? 133.824 83.555  77.188  1.00 68.93  ? 486  GLU   C N     1 
ATOM   2608 C CA    . GLU   A 1 486  ? 133.829 82.137  76.846  1.00 73.51  ? 486  GLU   C CA    1 
ATOM   2609 C C     . GLU   A 1 486  ? 134.533 81.914  75.511  1.00 75.51  ? 486  GLU   C C     1 
ATOM   2610 O O     . GLU   A 1 486  ? 135.243 80.923  75.339  1.00 75.02  ? 486  GLU   C O     1 
ATOM   2611 C CB    . GLU   A 1 486  ? 132.413 81.564  76.795  1.00 76.80  ? 486  GLU   C CB    1 
ATOM   2612 C CG    . GLU   A 1 486  ? 132.381 80.063  76.520  1.00 85.30  ? 486  GLU   C CG    1 
ATOM   2613 C CD    . GLU   A 1 486  ? 131.005 79.464  76.587  1.00 86.24  ? 486  GLU   C CD    1 
ATOM   2614 O OE1   . GLU   A 1 486  ? 130.065 80.195  76.783  1.00 93.60  ? 486  GLU   C OE1   1 
ATOM   2615 O OE2   . GLU   A 1 486  ? 130.895 78.261  76.445  1.00 96.49  ? 486  GLU   C OE2   1 
ATOM   2616 N N     . SER   A 1 487  ? 134.348 82.842  74.569  1.00 69.59  ? 487  SER   C N     1 
ATOM   2617 C CA    . SER   A 1 487  ? 134.975 82.752  73.256  1.00 70.63  ? 487  SER   C CA    1 
ATOM   2618 C C     . SER   A 1 487  ? 136.501 82.770  73.345  1.00 70.95  ? 487  SER   C C     1 
ATOM   2619 O O     . SER   A 1 487  ? 137.182 82.188  72.501  1.00 71.32  ? 487  SER   C O     1 
ATOM   2620 C CB    . SER   A 1 487  ? 134.511 83.901  72.377  1.00 79.78  ? 487  SER   C CB    1 
ATOM   2621 O OG    . SER   A 1 487  ? 133.143 83.795  72.086  1.00 82.27  ? 487  SER   C OG    1 
ATOM   2622 N N     . ASP   A 1 488  ? 137.044 83.425  74.371  1.00 77.63  ? 488  ASP   C N     1 
ATOM   2623 C CA    . ASP   A 1 488  ? 138.490 83.530  74.510  1.00 72.58  ? 488  ASP   C CA    1 
ATOM   2624 C C     . ASP   A 1 488  ? 139.048 82.237  75.068  1.00 71.67  ? 488  ASP   C C     1 
ATOM   2625 O O     . ASP   A 1 488  ? 140.183 81.857  74.776  1.00 73.60  ? 488  ASP   C O     1 
ATOM   2626 C CB    . ASP   A 1 488  ? 138.879 84.685  75.435  1.00 65.60  ? 488  ASP   C CB    1 
ATOM   2627 C CG    . ASP   A 1 488  ? 138.523 86.044  74.876  1.00 67.44  ? 488  ASP   C CG    1 
ATOM   2628 O OD1   . ASP   A 1 488  ? 138.823 86.305  73.732  1.00 71.97  ? 488  ASP   C OD1   1 
ATOM   2629 O OD2   . ASP   A 1 488  ? 137.968 86.837  75.613  1.00 66.60  ? 488  ASP   C OD2   1 
ATOM   2630 N N     . LEU   A 1 489  ? 138.240 81.546  75.860  1.00 70.51  ? 489  LEU   C N     1 
ATOM   2631 C CA    . LEU   A 1 489  ? 138.667 80.267  76.396  1.00 71.04  ? 489  LEU   C CA    1 
ATOM   2632 C C     . LEU   A 1 489  ? 138.590 79.217  75.290  1.00 63.47  ? 489  LEU   C C     1 
ATOM   2633 O O     . LEU   A 1 489  ? 139.503 78.407  75.114  1.00 86.20  ? 489  LEU   C O     1 
ATOM   2634 C CB    . LEU   A 1 489  ? 137.767 79.854  77.568  1.00 66.69  ? 489  LEU   C CB    1 
ATOM   2635 C CG    . LEU   A 1 489  ? 137.764 80.785  78.801  1.00 63.93  ? 489  LEU   C CG    1 
ATOM   2636 C CD1   . LEU   A 1 489  ? 136.720 80.288  79.793  1.00 63.58  ? 489  LEU   C CD1   1 
ATOM   2637 C CD2   . LEU   A 1 489  ? 139.134 80.814  79.436  1.00 66.40  ? 489  LEU   C CD2   1 
ATOM   2638 N N     . ARG   A 1 490  ? 137.523 79.281  74.496  1.00 79.19  ? 490  ARG   C N     1 
ATOM   2639 C CA    . ARG   A 1 490  ? 137.322 78.334  73.408  1.00 81.89  ? 490  ARG   C CA    1 
ATOM   2640 C C     . ARG   A 1 490  ? 138.438 78.437  72.376  1.00 78.74  ? 490  ARG   C C     1 
ATOM   2641 O O     . ARG   A 1 490  ? 138.904 77.427  71.845  1.00 72.35  ? 490  ARG   C O     1 
ATOM   2642 C CB    . ARG   A 1 490  ? 135.984 78.577  72.727  1.00 81.88  ? 490  ARG   C CB    1 
ATOM   2643 C CG    . ARG   A 1 490  ? 134.764 78.241  73.573  1.00 84.66  ? 490  ARG   C CG    1 
ATOM   2644 C CD    . ARG   A 1 490  ? 133.503 78.512  72.855  1.00 91.39  ? 490  ARG   C CD    1 
ATOM   2645 N NE    . ARG   A 1 490  ? 133.270 77.542  71.795  1.00 97.18  ? 490  ARG   C NE    1 
ATOM   2646 C CZ    . ARG   A 1 490  ? 132.443 77.729  70.748  1.00 99.56  ? 490  ARG   C CZ    1 
ATOM   2647 N NH1   . ARG   A 1 490  ? 131.777 78.859  70.625  1.00 102.05 ? 490  ARG   C NH1   1 
ATOM   2648 N NH2   . ARG   A 1 490  ? 132.299 76.775  69.845  1.00 103.55 ? 490  ARG   C NH2   1 
ATOM   2649 N N     . ASN   A 1 491  ? 138.901 79.657  72.125  1.00 75.58  ? 491  ASN   C N     1 
ATOM   2650 C CA    . ASN   A 1 491  ? 139.939 79.907  71.133  1.00 73.74  ? 491  ASN   C CA    1 
ATOM   2651 C C     . ASN   A 1 491  ? 141.299 79.338  71.531  1.00 75.25  ? 491  ASN   C C     1 
ATOM   2652 O O     . ASN   A 1 491  ? 142.210 79.268  70.705  1.00 72.74  ? 491  ASN   C O     1 
ATOM   2653 C CB    . ASN   A 1 491  ? 140.054 81.393  70.859  1.00 73.41  ? 491  ASN   C CB    1 
ATOM   2654 C CG    . ASN   A 1 491  ? 138.896 81.921  70.058  1.00 75.22  ? 491  ASN   C CG    1 
ATOM   2655 O OD1   . ASN   A 1 491  ? 138.177 81.159  69.399  1.00 79.90  ? 491  ASN   C OD1   1 
ATOM   2656 N ND2   . ASN   A 1 491  ? 138.701 83.213  70.098  1.00 79.72  ? 491  ASN   C ND2   1 
ATOM   2657 N N     . HIS   A 1 492  ? 141.446 78.939  72.793  1.00 73.57  ? 492  HIS   C N     1 
ATOM   2658 C CA    . HIS   A 1 492  ? 142.689 78.347  73.268  1.00 69.06  ? 492  HIS   C CA    1 
ATOM   2659 C C     . HIS   A 1 492  ? 142.520 76.851  73.495  1.00 71.63  ? 492  HIS   C C     1 
ATOM   2660 O O     . HIS   A 1 492  ? 143.401 76.192  74.049  1.00 69.16  ? 492  HIS   C O     1 
ATOM   2661 C CB    . HIS   A 1 492  ? 143.168 79.028  74.555  1.00 64.83  ? 492  HIS   C CB    1 
ATOM   2662 C CG    . HIS   A 1 492  ? 143.710 80.408  74.342  1.00 61.14  ? 492  HIS   C CG    1 
ATOM   2663 N ND1   . HIS   A 1 492  ? 142.912 81.529  74.264  1.00 62.79  ? 492  HIS   C ND1   1 
ATOM   2664 C CD2   . HIS   A 1 492  ? 144.981 80.839  74.191  1.00 60.22  ? 492  HIS   C CD2   1 
ATOM   2665 C CE1   . HIS   A 1 492  ? 143.674 82.593  74.073  1.00 59.28  ? 492  HIS   C CE1   1 
ATOM   2666 N NE2   . HIS   A 1 492  ? 144.934 82.197  74.025  1.00 56.54  ? 492  HIS   C NE2   1 
ATOM   2667 N N     . GLY   A 1 493  ? 141.378 76.321  73.062  1.00 75.03  ? 493  GLY   C N     1 
ATOM   2668 C CA    . GLY   A 1 493  ? 141.078 74.906  73.214  1.00 75.65  ? 493  GLY   C CA    1 
ATOM   2669 C C     . GLY   A 1 493  ? 140.654 74.561  74.635  1.00 75.85  ? 493  GLY   C C     1 
ATOM   2670 O O     . GLY   A 1 493  ? 140.767 73.409  75.057  1.00 79.79  ? 493  GLY   C O     1 
ATOM   2671 N N     . LEU   A 1 494  ? 140.186 75.557  75.383  1.00 74.86  ? 494  LEU   C N     1 
ATOM   2672 C CA    . LEU   A 1 494  ? 139.790 75.355  76.769  1.00 76.39  ? 494  LEU   C CA    1 
ATOM   2673 C C     . LEU   A 1 494  ? 138.283 75.496  76.907  1.00 85.18  ? 494  LEU   C C     1 
ATOM   2674 O O     . LEU   A 1 494  ? 137.780 76.589  77.159  1.00 77.33  ? 494  LEU   C O     1 
ATOM   2675 C CB    . LEU   A 1 494  ? 140.477 76.406  77.654  1.00 74.75  ? 494  LEU   C CB    1 
ATOM   2676 C CG    . LEU   A 1 494  ? 142.007 76.515  77.516  1.00 68.65  ? 494  LEU   C CG    1 
ATOM   2677 C CD1   . LEU   A 1 494  ? 142.482 77.756  78.259  1.00 62.17  ? 494  LEU   C CD1   1 
ATOM   2678 C CD2   . LEU   A 1 494  ? 142.670 75.266  78.075  1.00 67.45  ? 494  LEU   C CD2   1 
ATOM   2679 N N     . GLN   A 1 495  ? 137.548 74.407  76.717  1.00 88.42  ? 495  GLN   C N     1 
ATOM   2680 C CA    . GLN   A 1 495  ? 136.095 74.519  76.750  1.00 90.09  ? 495  GLN   C CA    1 
ATOM   2681 C C     . GLN   A 1 495  ? 135.390 73.217  77.094  1.00 95.29  ? 495  GLN   C C     1 
ATOM   2682 O O     . GLN   A 1 495  ? 135.761 72.148  76.612  1.00 87.92  ? 495  GLN   C O     1 
ATOM   2683 C CB    . GLN   A 1 495  ? 135.586 75.036  75.403  1.00 86.26  ? 495  GLN   C CB    1 
ATOM   2684 C CG    . GLN   A 1 495  ? 135.910 74.127  74.217  1.00 90.23  ? 495  GLN   C CG    1 
ATOM   2685 C CD    . GLN   A 1 495  ? 135.539 74.744  72.875  1.00 94.81  ? 495  GLN   C CD    1 
ATOM   2686 O OE1   . GLN   A 1 495  ? 134.375 75.071  72.619  1.00 94.94  ? 495  GLN   C OE1   1 
ATOM   2687 N NE2   . GLN   A 1 495  ? 136.534 74.907  72.009  1.00 88.79  ? 495  GLN   C NE2   1 
ATOM   2688 N N     . LYS   A 1 496  ? 134.335 73.336  77.896  1.00 96.98  ? 496  LYS   C N     1 
ATOM   2689 C CA    . LYS   A 1 496  ? 133.452 72.224  78.240  1.00 100.11 ? 496  LYS   C CA    1 
ATOM   2690 C C     . LYS   A 1 496  ? 134.211 71.013  78.773  1.00 97.28  ? 496  LYS   C C     1 
ATOM   2691 O O     . LYS   A 1 496  ? 133.866 69.871  78.467  1.00 92.49  ? 496  LYS   C O     1 
ATOM   2692 C CB    . LYS   A 1 496  ? 132.614 71.825  77.025  1.00 99.57  ? 496  LYS   C CB    1 
ATOM   2693 C CG    . LYS   A 1 496  ? 131.807 72.972  76.403  1.00 99.68  ? 496  LYS   C CG    1 
ATOM   2694 C CD    . LYS   A 1 496  ? 130.631 73.395  77.294  1.00 106.23 ? 496  LYS   C CD    1 
ATOM   2695 C CE    . LYS   A 1 496  ? 129.701 74.380  76.570  1.00 99.18  ? 496  LYS   C CE    1 
ATOM   2696 N NZ    . LYS   A 1 496  ? 130.282 75.763  76.474  1.00 97.79  ? 496  LYS   C NZ    1 
ATOM   2697 N N     . ALA   A 1 497  ? 135.232 71.263  79.585  1.00 91.51  ? 497  ALA   C N     1 
ATOM   2698 C CA    . ALA   A 1 497  ? 136.026 70.192  80.170  1.00 84.69  ? 497  ALA   C CA    1 
ATOM   2699 C C     . ALA   A 1 497  ? 136.847 70.693  81.355  1.00 78.89  ? 497  ALA   C C     1 
ATOM   2700 O O     . ALA   A 1 497  ? 136.421 70.608  82.509  1.00 85.08  ? 497  ALA   C O     1 
ATOM   2701 C CB    . ALA   A 1 497  ? 136.943 69.585  79.117  1.00 86.24  ? 497  ALA   C CB    1 
ATOM   2702 N N     . ASP   A 1 498  ? 138.046 71.183  81.061  1.00 81.72  ? 498  ASP   C N     1 
ATOM   2703 C CA    . ASP   A 1 498  ? 138.993 71.585  82.084  1.00 75.43  ? 498  ASP   C CA    1 
ATOM   2704 C C     . ASP   A 1 498  ? 138.589 72.877  82.772  1.00 98.42  ? 498  ASP   C C     1 
ATOM   2705 O O     . ASP   A 1 498  ? 138.915 73.088  83.938  1.00 62.75  ? 498  ASP   C O     1 
ATOM   2706 C CB    . ASP   A 1 498  ? 140.370 71.732  81.458  1.00 79.06  ? 498  ASP   C CB    1 
ATOM   2707 C CG    . ASP   A 1 498  ? 140.327 72.656  80.285  1.00 81.14  ? 498  ASP   C CG    1 
ATOM   2708 O OD1   . ASP   A 1 498  ? 139.396 72.531  79.513  1.00 82.09  ? 498  ASP   C OD1   1 
ATOM   2709 O OD2   . ASP   A 1 498  ? 141.193 73.480  80.154  1.00 79.49  ? 498  ASP   C OD2   1 
ATOM   2710 N N     . VAL   A 1 499  ? 137.825 73.716  82.083  1.00 74.96  ? 499  VAL   C N     1 
ATOM   2711 C CA    . VAL   A 1 499  ? 137.386 74.963  82.687  1.00 71.52  ? 499  VAL   C CA    1 
ATOM   2712 C C     . VAL   A 1 499  ? 136.561 74.651  83.925  1.00 74.65  ? 499  VAL   C C     1 
ATOM   2713 O O     . VAL   A 1 499  ? 136.717 75.299  84.959  1.00 84.21  ? 499  VAL   C O     1 
ATOM   2714 C CB    . VAL   A 1 499  ? 136.561 75.803  81.691  1.00 70.38  ? 499  VAL   C CB    1 
ATOM   2715 C CG1   . VAL   A 1 499  ? 135.952 77.023  82.400  1.00 65.79  ? 499  VAL   C CG1   1 
ATOM   2716 C CG2   . VAL   A 1 499  ? 137.464 76.242  80.530  1.00 74.36  ? 499  VAL   C CG2   1 
ATOM   2717 N N     . SER   A 1 500  ? 135.697 73.643  83.821  1.00 77.63  ? 500  SER   C N     1 
ATOM   2718 C CA    . SER   A 1 500  ? 134.886 73.226  84.956  1.00 80.33  ? 500  SER   C CA    1 
ATOM   2719 C C     . SER   A 1 500  ? 135.776 72.679  86.062  1.00 79.19  ? 500  SER   C C     1 
ATOM   2720 O O     . SER   A 1 500  ? 135.541 72.938  87.246  1.00 79.23  ? 500  SER   C O     1 
ATOM   2721 C CB    . SER   A 1 500  ? 133.883 72.169  84.532  1.00 75.21  ? 500  SER   C CB    1 
ATOM   2722 O OG    . SER   A 1 500  ? 132.934 72.694  83.643  1.00 78.48  ? 500  SER   C OG    1 
ATOM   2723 N N     . ALA   A 1 501  ? 136.808 71.931  85.681  1.00 79.00  ? 501  ALA   C N     1 
ATOM   2724 C CA    . ALA   A 1 501  ? 137.751 71.385  86.652  1.00 78.83  ? 501  ALA   C CA    1 
ATOM   2725 C C     . ALA   A 1 501  ? 138.491 72.503  87.383  1.00 88.93  ? 501  ALA   C C     1 
ATOM   2726 O O     . ALA   A 1 501  ? 138.736 72.415  88.586  1.00 69.60  ? 501  ALA   C O     1 
ATOM   2727 C CB    . ALA   A 1 501  ? 138.747 70.464  85.970  1.00 79.59  ? 501  ALA   C CB    1 
ATOM   2728 N N     . PHE   A 1 502  ? 138.825 73.562  86.651  1.00 70.93  ? 502  PHE   C N     1 
ATOM   2729 C CA    . PHE   A 1 502  ? 139.539 74.690  87.227  1.00 69.76  ? 502  PHE   C CA    1 
ATOM   2730 C C     . PHE   A 1 502  ? 138.647 75.423  88.219  1.00 66.70  ? 502  PHE   C C     1 
ATOM   2731 O O     . PHE   A 1 502  ? 139.121 75.917  89.249  1.00 71.94  ? 502  PHE   C O     1 
ATOM   2732 C CB    . PHE   A 1 502  ? 139.995 75.655  86.135  1.00 68.65  ? 502  PHE   C CB    1 
ATOM   2733 C CG    . PHE   A 1 502  ? 140.990 75.085  85.139  1.00 68.48  ? 502  PHE   C CG    1 
ATOM   2734 C CD1   . PHE   A 1 502  ? 141.085 75.635  83.865  1.00 68.45  ? 502  PHE   C CD1   1 
ATOM   2735 C CD2   . PHE   A 1 502  ? 141.823 74.011  85.457  1.00 72.57  ? 502  PHE   C CD2   1 
ATOM   2736 C CE1   . PHE   A 1 502  ? 141.978 75.130  82.942  1.00 68.12  ? 502  PHE   C CE1   1 
ATOM   2737 C CE2   . PHE   A 1 502  ? 142.714 73.513  84.531  1.00 71.69  ? 502  PHE   C CE2   1 
ATOM   2738 C CZ    . PHE   A 1 502  ? 142.791 74.072  83.275  1.00 66.70  ? 502  PHE   C CZ    1 
ATOM   2739 N N     . LEU   A 1 503  ? 137.349 75.485  87.919  1.00 62.25  ? 503  LEU   C N     1 
ATOM   2740 C CA    . LEU   A 1 503  ? 136.405 76.098  88.843  1.00 61.59  ? 503  LEU   C CA    1 
ATOM   2741 C C     . LEU   A 1 503  ? 136.281 75.241  90.106  1.00 71.52  ? 503  LEU   C C     1 
ATOM   2742 O O     . LEU   A 1 503  ? 136.299 75.756  91.220  1.00 64.17  ? 503  LEU   C O     1 
ATOM   2743 C CB    . LEU   A 1 503  ? 135.009 76.230  88.198  1.00 71.67  ? 503  LEU   C CB    1 
ATOM   2744 C CG    . LEU   A 1 503  ? 134.858 77.186  86.978  1.00 65.80  ? 503  LEU   C CG    1 
ATOM   2745 C CD1   . LEU   A 1 503  ? 133.474 76.996  86.377  1.00 76.25  ? 503  LEU   C CD1   1 
ATOM   2746 C CD2   . LEU   A 1 503  ? 135.050 78.623  87.402  1.00 58.22  ? 503  LEU   C CD2   1 
ATOM   2747 N N     . ARG   A 1 504  ? 136.198 73.921  89.940  1.00 76.80  ? 504  ARG   C N     1 
ATOM   2748 C CA    . ARG   A 1 504  ? 136.040 73.031  91.092  1.00 78.65  ? 504  ARG   C CA    1 
ATOM   2749 C C     . ARG   A 1 504  ? 137.227 73.113  92.043  1.00 69.19  ? 504  ARG   C C     1 
ATOM   2750 O O     . ARG   A 1 504  ? 137.061 73.062  93.262  1.00 76.26  ? 504  ARG   C O     1 
ATOM   2751 C CB    . ARG   A 1 504  ? 135.867 71.580  90.662  1.00 78.41  ? 504  ARG   C CB    1 
ATOM   2752 C CG    . ARG   A 1 504  ? 134.532 71.237  90.023  1.00 81.12  ? 504  ARG   C CG    1 
ATOM   2753 C CD    . ARG   A 1 504  ? 134.321 69.766  89.972  1.00 98.85  ? 504  ARG   C CD    1 
ATOM   2754 N NE    . ARG   A 1 504  ? 135.319 69.074  89.154  1.00 88.49  ? 504  ARG   C NE    1 
ATOM   2755 C CZ    . ARG   A 1 504  ? 135.221 68.858  87.824  1.00 83.23  ? 504  ARG   C CZ    1 
ATOM   2756 N NH1   . ARG   A 1 504  ? 134.178 69.294  87.154  1.00 86.51  ? 504  ARG   C NH1   1 
ATOM   2757 N NH2   . ARG   A 1 504  ? 136.180 68.201  87.193  1.00 81.99  ? 504  ARG   C NH2   1 
ATOM   2758 N N     . MET   A 1 505  ? 138.424 73.244  91.482  1.00 72.86  ? 505  MET   C N     1 
ATOM   2759 C CA    . MET   A 1 505  ? 139.648 73.285  92.270  1.00 86.67  ? 505  MET   C CA    1 
ATOM   2760 C C     . MET   A 1 505  ? 140.015 74.682  92.760  1.00 62.85  ? 505  MET   C C     1 
ATOM   2761 O O     . MET   A 1 505  ? 141.065 74.871  93.375  1.00 68.49  ? 505  MET   C O     1 
ATOM   2762 C CB    . MET   A 1 505  ? 140.800 72.714  91.466  1.00 77.54  ? 505  MET   C CB    1 
ATOM   2763 C CG    . MET   A 1 505  ? 140.688 71.227  91.167  1.00 77.22  ? 505  MET   C CG    1 
ATOM   2764 S SD    . MET   A 1 505  ? 140.574 70.205  92.665  1.00 126.37 ? 505  MET   C SD    1 
ATOM   2765 C CE    . MET   A 1 505  ? 142.248 70.281  93.300  1.00 76.38  ? 505  MET   C CE    1 
ATOM   2766 N N     . ASN   A 1 506  ? 139.160 75.659  92.492  1.00 78.07  ? 506  ASN   C N     1 
ATOM   2767 C CA    . ASN   A 1 506  ? 139.400 77.037  92.902  1.00 69.75  ? 506  ASN   C CA    1 
ATOM   2768 C C     . ASN   A 1 506  ? 140.692 77.614  92.335  1.00 57.09  ? 506  ASN   C C     1 
ATOM   2769 O O     . ASN   A 1 506  ? 141.439 78.286  93.046  1.00 62.79  ? 506  ASN   C O     1 
ATOM   2770 C CB    . ASN   A 1 506  ? 139.390 77.145  94.419  1.00 70.17  ? 506  ASN   C CB    1 
ATOM   2771 C CG    . ASN   A 1 506  ? 139.145 78.542  94.907  1.00 72.51  ? 506  ASN   C CG    1 
ATOM   2772 O OD1   . ASN   A 1 506  ? 138.618 79.394  94.183  1.00 76.95  ? 506  ASN   C OD1   1 
ATOM   2773 N ND2   . ASN   A 1 506  ? 139.503 78.790  96.134  1.00 69.34  ? 506  ASN   C ND2   1 
ATOM   2774 N N     . LEU   A 1 507  ? 140.943 77.376  91.049  1.00 54.68  ? 507  LEU   C N     1 
ATOM   2775 C CA    . LEU   A 1 507  ? 142.072 77.996  90.357  1.00 58.75  ? 507  LEU   C CA    1 
ATOM   2776 C C     . LEU   A 1 507  ? 141.582 79.154  89.510  1.00 46.81  ? 507  LEU   C C     1 
ATOM   2777 O O     . LEU   A 1 507  ? 142.293 80.141  89.292  1.00 41.44  ? 507  LEU   C O     1 
ATOM   2778 C CB    . LEU   A 1 507  ? 142.797 76.996  89.445  1.00 57.96  ? 507  LEU   C CB    1 
ATOM   2779 C CG    . LEU   A 1 507  ? 143.976 77.582  88.617  1.00 40.28  ? 507  LEU   C CG    1 
ATOM   2780 C CD1   . LEU   A 1 507  ? 145.041 78.130  89.564  1.00 39.98  ? 507  LEU   C CD1   1 
ATOM   2781 C CD2   . LEU   A 1 507  ? 144.551 76.492  87.710  1.00 44.86  ? 507  LEU   C CD2   1 
ATOM   2782 N N     . PHE   A 1 508  ? 140.372 78.994  88.996  1.00 50.13  ? 508  PHE   C N     1 
ATOM   2783 C CA    . PHE   A 1 508  ? 139.773 79.915  88.051  1.00 45.06  ? 508  PHE   C CA    1 
ATOM   2784 C C     . PHE   A 1 508  ? 138.363 80.239  88.555  1.00 45.18  ? 508  PHE   C C     1 
ATOM   2785 O O     . PHE   A 1 508  ? 137.734 79.393  89.188  1.00 58.61  ? 508  PHE   C O     1 
ATOM   2786 C CB    . PHE   A 1 508  ? 139.791 79.222  86.684  1.00 50.06  ? 508  PHE   C CB    1 
ATOM   2787 C CG    . PHE   A 1 508  ? 139.805 80.067  85.454  1.00 41.26  ? 508  PHE   C CG    1 
ATOM   2788 C CD1   . PHE   A 1 508  ? 140.875 80.911  85.187  1.00 45.04  ? 508  PHE   C CD1   1 
ATOM   2789 C CD2   . PHE   A 1 508  ? 138.803 79.966  84.521  1.00 47.19  ? 508  PHE   C CD2   1 
ATOM   2790 C CE1   . PHE   A 1 508  ? 140.923 81.647  84.028  1.00 49.11  ? 508  PHE   C CE1   1 
ATOM   2791 C CE2   . PHE   A 1 508  ? 138.857 80.698  83.360  1.00 53.41  ? 508  PHE   C CE2   1 
ATOM   2792 C CZ    . PHE   A 1 508  ? 139.918 81.541  83.117  1.00 52.42  ? 508  PHE   C CZ    1 
ATOM   2793 N N     . GLN   A 1 509  ? 137.883 81.457  88.312  1.00 41.50  ? 509  GLN   C N     1 
ATOM   2794 C CA    . GLN   A 1 509  ? 136.552 81.879  88.760  1.00 45.55  ? 509  GLN   C CA    1 
ATOM   2795 C C     . GLN   A 1 509  ? 135.645 82.259  87.593  1.00 51.80  ? 509  GLN   C C     1 
ATOM   2796 O O     . GLN   A 1 509  ? 136.121 82.695  86.544  1.00 51.75  ? 509  GLN   C O     1 
ATOM   2797 C CB    . GLN   A 1 509  ? 136.669 83.061  89.724  1.00 45.35  ? 509  GLN   C CB    1 
ATOM   2798 C CG    . GLN   A 1 509  ? 137.423 82.737  90.986  1.00 45.07  ? 509  GLN   C CG    1 
ATOM   2799 C CD    . GLN   A 1 509  ? 137.553 83.916  91.934  1.00 50.57  ? 509  GLN   C CD    1 
ATOM   2800 O OE1   . GLN   A 1 509  ? 137.482 85.077  91.520  1.00 47.27  ? 509  GLN   C OE1   1 
ATOM   2801 N NE2   . GLN   A 1 509  ? 137.747 83.619  93.215  1.00 53.53  ? 509  GLN   C NE2   1 
ATOM   2802 N N     . LYS   A 1 510  ? 134.332 82.116  87.785  1.00 55.61  ? 510  LYS   C N     1 
ATOM   2803 C CA    . LYS   A 1 510  ? 133.356 82.459  86.752  1.00 58.56  ? 510  LYS   C CA    1 
ATOM   2804 C C     . LYS   A 1 510  ? 132.757 83.854  86.919  1.00 66.63  ? 510  LYS   C C     1 
ATOM   2805 O O     . LYS   A 1 510  ? 132.037 84.323  86.041  1.00 69.68  ? 510  LYS   C O     1 
ATOM   2806 C CB    . LYS   A 1 510  ? 132.235 81.422  86.719  1.00 66.19  ? 510  LYS   C CB    1 
ATOM   2807 C CG    . LYS   A 1 510  ? 131.221 81.608  85.602  1.00 65.88  ? 510  LYS   C CG    1 
ATOM   2808 C CD    . LYS   A 1 510  ? 130.297 80.413  85.496  1.00 63.31  ? 510  LYS   C CD    1 
ATOM   2809 C CE    . LYS   A 1 510  ? 129.237 80.632  84.436  1.00 70.15  ? 510  LYS   C CE    1 
ATOM   2810 N NZ    . LYS   A 1 510  ? 128.313 79.470  84.332  1.00 83.54  ? 510  LYS   C NZ    1 
ATOM   2811 N N     . GLU   A 1 511  ? 132.989 84.481  88.071  1.00 66.26  ? 511  GLU   C N     1 
ATOM   2812 C CA    . GLU   A 1 511  ? 132.366 85.768  88.389  1.00 66.06  ? 511  GLU   C CA    1 
ATOM   2813 C C     . GLU   A 1 511  ? 130.859 85.715  88.166  1.00 74.93  ? 511  GLU   C C     1 
ATOM   2814 O O     . GLU   A 1 511  ? 130.322 86.365  87.272  1.00 72.40  ? 511  GLU   C O     1 
ATOM   2815 C CB    . GLU   A 1 511  ? 132.981 86.922  87.587  1.00 68.31  ? 511  GLU   C CB    1 
ATOM   2816 C CG    . GLU   A 1 511  ? 134.457 87.169  87.867  1.00 64.43  ? 511  GLU   C CG    1 
ATOM   2817 C CD    . GLU   A 1 511  ? 134.905 88.556  87.471  1.00 56.70  ? 511  GLU   C CD    1 
ATOM   2818 O OE1   . GLU   A 1 511  ? 134.291 89.140  86.612  1.00 57.19  ? 511  GLU   C OE1   1 
ATOM   2819 O OE2   . GLU   A 1 511  ? 135.849 89.042  88.063  1.00 54.44  ? 511  GLU   C OE2   1 
ATOM   2820 N N     . VAL   A 1 512  ? 130.188 84.916  88.986  1.00 79.67  ? 512  VAL   C N     1 
ATOM   2821 C CA    . VAL   A 1 512  ? 128.760 84.634  88.852  1.00 91.38  ? 512  VAL   C CA    1 
ATOM   2822 C C     . VAL   A 1 512  ? 127.843 85.782  89.271  1.00 84.38  ? 512  VAL   C C     1 
ATOM   2823 O O     . VAL   A 1 512  ? 126.620 85.665  89.181  1.00 86.28  ? 512  VAL   C O     1 
ATOM   2824 C CB    . VAL   A 1 512  ? 128.388 83.373  89.661  1.00 92.31  ? 512  VAL   C CB    1 
ATOM   2825 C CG1   . VAL   A 1 512  ? 129.164 82.183  89.128  1.00 80.46  ? 512  VAL   C CG1   1 
ATOM   2826 C CG2   . VAL   A 1 512  ? 128.697 83.591  91.156  1.00 90.16  ? 512  VAL   C CG2   1 
ATOM   2827 N N     . ASP   A 1 513  ? 128.412 86.887  89.741  1.00 85.78  ? 513  ASP   C N     1 
ATOM   2828 C CA    . ASP   A 1 513  ? 127.584 88.002  90.186  1.00 90.32  ? 513  ASP   C CA    1 
ATOM   2829 C C     . ASP   A 1 513  ? 127.046 88.807  89.009  1.00 86.16  ? 513  ASP   C C     1 
ATOM   2830 O O     . ASP   A 1 513  ? 127.515 89.910  88.726  1.00 90.16  ? 513  ASP   C O     1 
ATOM   2831 C CB    . ASP   A 1 513  ? 128.365 88.937  91.112  1.00 86.95  ? 513  ASP   C CB    1 
ATOM   2832 C CG    . ASP   A 1 513  ? 127.469 90.009  91.749  1.00 87.00  ? 513  ASP   C CG    1 
ATOM   2833 O OD1   . ASP   A 1 513  ? 126.281 89.789  91.822  1.00 94.73  ? 513  ASP   C OD1   1 
ATOM   2834 O OD2   . ASP   A 1 513  ? 127.980 91.037  92.148  1.00 85.31  ? 513  ASP   C OD2   1 
ATOM   2835 N N     . CYS   A 1 514  ? 126.046 88.243  88.337  1.00 81.93  ? 514  CYS   C N     1 
ATOM   2836 C CA    . CYS   A 1 514  ? 125.389 88.877  87.198  1.00 88.34  ? 514  CYS   C CA    1 
ATOM   2837 C C     . CYS   A 1 514  ? 126.362 89.201  86.073  1.00 82.98  ? 514  CYS   C C     1 
ATOM   2838 O O     . CYS   A 1 514  ? 126.311 90.290  85.500  1.00 90.07  ? 514  CYS   C O     1 
ATOM   2839 C CB    . CYS   A 1 514  ? 124.702 90.172  87.631  1.00 112.21 ? 514  CYS   C CB    1 
ATOM   2840 S SG    . CYS   A 1 514  ? 123.554 89.970  89.000  1.00 96.85  ? 514  CYS   C SG    1 
ATOM   2841 N N     . GLU   A 1 515  ? 127.237 88.256  85.755  1.00 90.04  ? 515  GLU   C N     1 
ATOM   2842 C CA    . GLU   A 1 515  ? 128.219 88.455  84.700  1.00 90.85  ? 515  GLU   C CA    1 
ATOM   2843 C C     . GLU   A 1 515  ? 128.629 87.112  84.099  1.00 77.49  ? 515  GLU   C C     1 
ATOM   2844 O O     . GLU   A 1 515  ? 128.445 86.066  84.720  1.00 79.32  ? 515  GLU   C O     1 
ATOM   2845 C CB    . GLU   A 1 515  ? 129.424 89.223  85.259  1.00 83.16  ? 515  GLU   C CB    1 
ATOM   2846 C CG    . GLU   A 1 515  ? 130.470 89.654  84.242  1.00 82.79  ? 515  GLU   C CG    1 
ATOM   2847 C CD    . GLU   A 1 515  ? 129.901 90.437  83.089  1.00 79.38  ? 515  GLU   C CD    1 
ATOM   2848 O OE1   . GLU   A 1 515  ? 129.330 89.824  82.217  1.00 78.69  ? 515  GLU   C OE1   1 
ATOM   2849 O OE2   . GLU   A 1 515  ? 130.055 91.633  83.069  1.00 92.79  ? 515  GLU   C OE2   1 
ATOM   2850 N N     . LYS   A 1 516  ? 129.159 87.137  82.878  1.00 80.69  ? 516  LYS   C N     1 
ATOM   2851 C CA    . LYS   A 1 516  ? 129.595 85.912  82.212  1.00 75.68  ? 516  LYS   C CA    1 
ATOM   2852 C C     . LYS   A 1 516  ? 131.071 85.913  81.807  1.00 73.56  ? 516  LYS   C C     1 
ATOM   2853 O O     . LYS   A 1 516  ? 131.437 85.298  80.805  1.00 71.42  ? 516  LYS   C O     1 
ATOM   2854 C CB    . LYS   A 1 516  ? 128.732 85.638  80.985  1.00 82.38  ? 516  LYS   C CB    1 
ATOM   2855 C CG    . LYS   A 1 516  ? 127.283 85.341  81.302  1.00 87.87  ? 516  LYS   C CG    1 
ATOM   2856 C CD    . LYS   A 1 516  ? 126.511 84.971  80.048  1.00 100.18 ? 516  LYS   C CD    1 
ATOM   2857 C CE    . LYS   A 1 516  ? 125.060 84.649  80.369  1.00 100.23 ? 516  LYS   C CE    1 
ATOM   2858 N NZ    . LYS   A 1 516  ? 124.294 84.287  79.148  1.00 94.63  ? 516  LYS   C NZ    1 
ATOM   2859 N N     . PHE   A 1 517  ? 131.916 86.587  82.579  1.00 66.78  ? 517  PHE   C N     1 
ATOM   2860 C CA    . PHE   A 1 517  ? 133.346 86.589  82.290  1.00 58.46  ? 517  PHE   C CA    1 
ATOM   2861 C C     . PHE   A 1 517  ? 134.114 85.765  83.304  1.00 54.24  ? 517  PHE   C C     1 
ATOM   2862 O O     . PHE   A 1 517  ? 133.783 85.750  84.481  1.00 61.09  ? 517  PHE   C O     1 
ATOM   2863 C CB    . PHE   A 1 517  ? 133.928 87.997  82.282  1.00 60.64  ? 517  PHE   C CB    1 
ATOM   2864 C CG    . PHE   A 1 517  ? 133.461 88.854  81.161  1.00 65.52  ? 517  PHE   C CG    1 
ATOM   2865 C CD1   . PHE   A 1 517  ? 132.702 89.968  81.408  1.00 67.57  ? 517  PHE   C CD1   1 
ATOM   2866 C CD2   . PHE   A 1 517  ? 133.777 88.541  79.854  1.00 62.71  ? 517  PHE   C CD2   1 
ATOM   2867 C CE1   . PHE   A 1 517  ? 132.259 90.763  80.378  1.00 70.13  ? 517  PHE   C CE1   1 
ATOM   2868 C CE2   . PHE   A 1 517  ? 133.338 89.329  78.815  1.00 64.59  ? 517  PHE   C CE2   1 
ATOM   2869 C CZ    . PHE   A 1 517  ? 132.575 90.443  79.078  1.00 71.30  ? 517  PHE   C CZ    1 
ATOM   2870 N N     . TYR   A 1 518  ? 135.170 85.128  82.837  1.00 54.58  ? 518  TYR   C N     1 
ATOM   2871 C CA    . TYR   A 1 518  ? 136.019 84.315  83.690  1.00 54.97  ? 518  TYR   C CA    1 
ATOM   2872 C C     . TYR   A 1 518  ? 137.319 85.027  84.041  1.00 50.06  ? 518  TYR   C C     1 
ATOM   2873 O O     . TYR   A 1 518  ? 137.781 85.903  83.313  1.00 50.84  ? 518  TYR   C O     1 
ATOM   2874 C CB    . TYR   A 1 518  ? 136.340 83.000  83.005  1.00 51.94  ? 518  TYR   C CB    1 
ATOM   2875 C CG    . TYR   A 1 518  ? 135.180 82.068  82.831  1.00 52.60  ? 518  TYR   C CG    1 
ATOM   2876 C CD1   . TYR   A 1 518  ? 134.312 82.226  81.768  1.00 59.46  ? 518  TYR   C CD1   1 
ATOM   2877 C CD2   . TYR   A 1 518  ? 135.002 81.034  83.726  1.00 53.92  ? 518  TYR   C CD2   1 
ATOM   2878 C CE1   . TYR   A 1 518  ? 133.259 81.351  81.606  1.00 63.19  ? 518  TYR   C CE1   1 
ATOM   2879 C CE2   . TYR   A 1 518  ? 133.957 80.161  83.566  1.00 55.88  ? 518  TYR   C CE2   1 
ATOM   2880 C CZ    . TYR   A 1 518  ? 133.086 80.311  82.511  1.00 60.86  ? 518  TYR   C CZ    1 
ATOM   2881 O OH    . TYR   A 1 518  ? 132.041 79.430  82.350  1.00 65.09  ? 518  TYR   C OH    1 
ATOM   2882 N N     . SER   A 1 519  ? 137.917 84.635  85.156  1.00 43.54  ? 519  SER   C N     1 
ATOM   2883 C CA    . SER   A 1 519  ? 139.192 85.217  85.561  1.00 40.43  ? 519  SER   C CA    1 
ATOM   2884 C C     . SER   A 1 519  ? 139.999 84.264  86.432  1.00 40.62  ? 519  SER   C C     1 
ATOM   2885 O O     . SER   A 1 519  ? 139.480 83.268  86.927  1.00 43.55  ? 519  SER   C O     1 
ATOM   2886 C CB    . SER   A 1 519  ? 138.946 86.511  86.305  1.00 41.25  ? 519  SER   C CB    1 
ATOM   2887 O OG    . SER   A 1 519  ? 138.276 86.277  87.509  1.00 46.19  ? 519  SER   C OG    1 
ATOM   2888 N N     . PHE   A 1 520  ? 141.273 84.588  86.627  1.00 38.31  ? 520  PHE   C N     1 
ATOM   2889 C CA    . PHE   A 1 520  ? 142.124 83.826  87.537  1.00 32.82  ? 520  PHE   C CA    1 
ATOM   2890 C C     . PHE   A 1 520  ? 141.864 84.280  88.966  1.00 34.42  ? 520  PHE   C C     1 
ATOM   2891 O O     . PHE   A 1 520  ? 141.494 85.430  89.189  1.00 38.86  ? 520  PHE   C O     1 
ATOM   2892 C CB    . PHE   A 1 520  ? 143.603 84.011  87.188  1.00 30.75  ? 520  PHE   C CB    1 
ATOM   2893 C CG    . PHE   A 1 520  ? 144.054 83.254  85.964  1.00 28.74  ? 520  PHE   C CG    1 
ATOM   2894 C CD1   . PHE   A 1 520  ? 144.111 83.865  84.722  1.00 32.02  ? 520  PHE   C CD1   1 
ATOM   2895 C CD2   . PHE   A 1 520  ? 144.436 81.922  86.064  1.00 27.09  ? 520  PHE   C CD2   1 
ATOM   2896 C CE1   . PHE   A 1 520  ? 144.535 83.160  83.608  1.00 35.10  ? 520  PHE   C CE1   1 
ATOM   2897 C CE2   . PHE   A 1 520  ? 144.857 81.222  84.957  1.00 27.37  ? 520  PHE   C CE2   1 
ATOM   2898 C CZ    . PHE   A 1 520  ? 144.907 81.840  83.729  1.00 27.85  ? 520  PHE   C CZ    1 
ATOM   2899 N N     . ILE   A 1 521  ? 142.067 83.389  89.934  1.00 32.61  ? 521  ILE   C N     1 
ATOM   2900 C CA    . ILE   A 1 521  ? 141.836 83.766  91.333  1.00 31.51  ? 521  ILE   C CA    1 
ATOM   2901 C C     . ILE   A 1 521  ? 142.720 84.916  91.794  1.00 26.77  ? 521  ILE   C C     1 
ATOM   2902 O O     . ILE   A 1 521  ? 142.332 85.683  92.679  1.00 32.57  ? 521  ILE   C O     1 
ATOM   2903 C CB    . ILE   A 1 521  ? 142.008 82.558  92.280  1.00 31.48  ? 521  ILE   C CB    1 
ATOM   2904 C CG1   . ILE   A 1 521  ? 143.423 81.952  92.121  1.00 34.25  ? 521  ILE   C CG1   1 
ATOM   2905 C CG2   . ILE   A 1 521  ? 140.911 81.545  92.042  1.00 43.25  ? 521  ILE   C CG2   1 
ATOM   2906 C CD1   . ILE   A 1 521  ? 143.746 80.867  93.120  1.00 37.74  ? 521  ILE   C CD1   1 
ATOM   2907 N N     . HIS   A 1 522  ? 143.894 85.070  91.198  1.00 23.81  ? 522  HIS   C N     1 
ATOM   2908 C CA    . HIS   A 1 522  ? 144.753 86.192  91.538  1.00 21.44  ? 522  HIS   C CA    1 
ATOM   2909 C C     . HIS   A 1 522  ? 145.717 86.506  90.404  1.00 22.91  ? 522  HIS   C C     1 
ATOM   2910 O O     . HIS   A 1 522  ? 146.124 85.614  89.654  1.00 23.22  ? 522  HIS   C O     1 
ATOM   2911 C CB    . HIS   A 1 522  ? 145.524 85.946  92.838  1.00 21.33  ? 522  HIS   C CB    1 
ATOM   2912 C CG    . HIS   A 1 522  ? 146.080 87.200  93.401  1.00 18.49  ? 522  HIS   C CG    1 
ATOM   2913 N ND1   . HIS   A 1 522  ? 147.266 87.749  92.967  1.00 23.41  ? 522  HIS   C ND1   1 
ATOM   2914 C CD2   . HIS   A 1 522  ? 145.604 88.036  94.341  1.00 15.77  ? 522  HIS   C CD2   1 
ATOM   2915 C CE1   . HIS   A 1 522  ? 147.487 88.875  93.619  1.00 18.40  ? 522  HIS   C CE1   1 
ATOM   2916 N NE2   . HIS   A 1 522  ? 146.499 89.069  94.453  1.00 15.53  ? 522  HIS   C NE2   1 
ATOM   2917 N N     . MET   A 1 523  ? 146.107 87.770  90.301  1.00 22.14  ? 523  MET   C N     1 
ATOM   2918 C CA    . MET   A 1 523  ? 147.035 88.202  89.263  1.00 20.69  ? 523  MET   C CA    1 
ATOM   2919 C C     . MET   A 1 523  ? 148.377 87.488  89.333  1.00 23.21  ? 523  MET   C C     1 
ATOM   2920 O O     . MET   A 1 523  ? 149.022 87.304  88.303  1.00 25.45  ? 523  MET   C O     1 
ATOM   2921 C CB    . MET   A 1 523  ? 147.263 89.705  89.335  1.00 21.99  ? 523  MET   C CB    1 
ATOM   2922 C CG    . MET   A 1 523  ? 146.088 90.546  88.883  1.00 30.70  ? 523  MET   C CG    1 
ATOM   2923 S SD    . MET   A 1 523  ? 145.520 90.123  87.221  1.00 40.50  ? 523  MET   C SD    1 
ATOM   2924 C CE    . MET   A 1 523  ? 146.916 90.595  86.202  1.00 29.97  ? 523  MET   C CE    1 
ATOM   2925 N N     . THR   A 1 524  ? 148.797 87.071  90.528  1.00 21.08  ? 524  THR   C N     1 
ATOM   2926 C CA    . THR   A 1 524  ? 150.062 86.359  90.633  1.00 16.59  ? 524  THR   C CA    1 
ATOM   2927 C C     . THR   A 1 524  ? 149.980 85.002  89.953  1.00 21.71  ? 524  THR   C C     1 
ATOM   2928 O O     . THR   A 1 524  ? 150.988 84.503  89.454  1.00 22.28  ? 524  THR   C O     1 
ATOM   2929 C CB    . THR   A 1 524  ? 150.494 86.162  92.093  1.00 12.10  ? 524  THR   C CB    1 
ATOM   2930 O OG1   . THR   A 1 524  ? 149.435 85.527  92.809  1.00 19.92  ? 524  THR   C OG1   1 
ATOM   2931 C CG2   . THR   A 1 524  ? 150.851 87.483  92.746  1.00 12.88  ? 524  THR   C CG2   1 
ATOM   2932 N N     . PHE   A 1 525  ? 148.788 84.406  89.903  1.00 21.81  ? 525  PHE   C N     1 
ATOM   2933 C CA    . PHE   A 1 525  ? 148.631 83.129  89.224  1.00 21.00  ? 525  PHE   C CA    1 
ATOM   2934 C C     . PHE   A 1 525  ? 148.651 83.332  87.725  1.00 22.49  ? 525  PHE   C C     1 
ATOM   2935 O O     . PHE   A 1 525  ? 149.257 82.551  86.995  1.00 26.93  ? 525  PHE   C O     1 
ATOM   2936 C CB    . PHE   A 1 525  ? 147.353 82.416  89.657  1.00 20.32  ? 525  PHE   C CB    1 
ATOM   2937 C CG    . PHE   A 1 525  ? 147.521 81.672  90.931  1.00 20.32  ? 525  PHE   C CG    1 
ATOM   2938 C CD1   . PHE   A 1 525  ? 147.145 82.221  92.140  1.00 19.71  ? 525  PHE   C CD1   1 
ATOM   2939 C CD2   . PHE   A 1 525  ? 148.076 80.413  90.919  1.00 23.44  ? 525  PHE   C CD2   1 
ATOM   2940 C CE1   . PHE   A 1 525  ? 147.321 81.521  93.314  1.00 20.87  ? 525  PHE   C CE1   1 
ATOM   2941 C CE2   . PHE   A 1 525  ? 148.255 79.714  92.080  1.00 25.63  ? 525  PHE   C CE2   1 
ATOM   2942 C CZ    . PHE   A 1 525  ? 147.878 80.266  93.284  1.00 24.53  ? 525  PHE   C CZ    1 
ATOM   2943 N N     . GLN   A 1 526  ? 148.013 84.402  87.264  1.00 22.28  ? 526  GLN   C N     1 
ATOM   2944 C CA    . GLN   A 1 526  ? 148.040 84.696  85.839  1.00 24.06  ? 526  GLN   C CA    1 
ATOM   2945 C C     . GLN   A 1 526  ? 149.467 84.978  85.381  1.00 25.02  ? 526  GLN   C C     1 
ATOM   2946 O O     . GLN   A 1 526  ? 149.918 84.445  84.367  1.00 30.13  ? 526  GLN   C O     1 
ATOM   2947 C CB    . GLN   A 1 526  ? 147.153 85.888  85.506  1.00 25.75  ? 526  GLN   C CB    1 
ATOM   2948 C CG    . GLN   A 1 526  ? 147.094 86.196  84.033  1.00 24.73  ? 526  GLN   C CG    1 
ATOM   2949 C CD    . GLN   A 1 526  ? 146.195 87.343  83.726  1.00 33.01  ? 526  GLN   C CD    1 
ATOM   2950 O OE1   . GLN   A 1 526  ? 145.337 87.715  84.528  1.00 36.10  ? 526  GLN   C OE1   1 
ATOM   2951 N NE2   . GLN   A 1 526  ? 146.382 87.919  82.554  1.00 35.04  ? 526  GLN   C NE2   1 
ATOM   2952 N N     . GLU   A 1 527  ? 150.185 85.796  86.148  1.00 23.47  ? 527  GLU   C N     1 
ATOM   2953 C CA    . GLU   A 1 527  ? 151.566 86.120  85.823  1.00 22.05  ? 527  GLU   C CA    1 
ATOM   2954 C C     . GLU   A 1 527  ? 152.462 84.893  85.933  1.00 22.05  ? 527  GLU   C C     1 
ATOM   2955 O O     . GLU   A 1 527  ? 153.376 84.717  85.128  1.00 26.13  ? 527  GLU   C O     1 
ATOM   2956 C CB    . GLU   A 1 527  ? 152.065 87.272  86.701  1.00 18.05  ? 527  GLU   C CB    1 
ATOM   2957 C CG    . GLU   A 1 527  ? 151.455 88.630  86.305  1.00 20.98  ? 527  GLU   C CG    1 
ATOM   2958 C CD    . GLU   A 1 527  ? 151.928 89.806  87.116  1.00 16.01  ? 527  GLU   C CD    1 
ATOM   2959 O OE1   . GLU   A 1 527  ? 151.951 89.717  88.315  1.00 15.91  ? 527  GLU   C OE1   1 
ATOM   2960 O OE2   . GLU   A 1 527  ? 152.278 90.802  86.526  1.00 16.74  ? 527  GLU   C OE2   1 
ATOM   2961 N N     . PHE   A 1 528  ? 152.182 84.027  86.903  1.00 22.41  ? 528  PHE   C N     1 
ATOM   2962 C CA    . PHE   A 1 528  ? 152.926 82.783  87.043  1.00 21.50  ? 528  PHE   C CA    1 
ATOM   2963 C C     . PHE   A 1 528  ? 152.817 81.945  85.778  1.00 25.52  ? 528  PHE   C C     1 
ATOM   2964 O O     . PHE   A 1 528  ? 153.820 81.470  85.246  1.00 30.07  ? 528  PHE   C O     1 
ATOM   2965 C CB    . PHE   A 1 528  ? 152.406 81.967  88.222  1.00 21.03  ? 528  PHE   C CB    1 
ATOM   2966 C CG    . PHE   A 1 528  ? 153.049 80.648  88.330  1.00 18.79  ? 528  PHE   C CG    1 
ATOM   2967 C CD1   . PHE   A 1 528  ? 154.254 80.510  88.968  1.00 21.74  ? 528  PHE   C CD1   1 
ATOM   2968 C CD2   . PHE   A 1 528  ? 152.464 79.540  87.777  1.00 22.98  ? 528  PHE   C CD2   1 
ATOM   2969 C CE1   . PHE   A 1 528  ? 154.865 79.291  89.053  1.00 24.28  ? 528  PHE   C CE1   1 
ATOM   2970 C CE2   . PHE   A 1 528  ? 153.071 78.326  87.860  1.00 23.61  ? 528  PHE   C CE2   1 
ATOM   2971 C CZ    . PHE   A 1 528  ? 154.269 78.199  88.494  1.00 23.29  ? 528  PHE   C CZ    1 
ATOM   2972 N N     . PHE   A 1 529  ? 151.592 81.762  85.295  1.00 27.02  ? 529  PHE   C N     1 
ATOM   2973 C CA    . PHE   A 1 529  ? 151.371 80.974  84.096  1.00 28.31  ? 529  PHE   C CA    1 
ATOM   2974 C C     . PHE   A 1 529  ? 152.020 81.621  82.878  1.00 31.86  ? 529  PHE   C C     1 
ATOM   2975 O O     . PHE   A 1 529  ? 152.576 80.928  82.028  1.00 37.15  ? 529  PHE   C O     1 
ATOM   2976 C CB    . PHE   A 1 529  ? 149.880 80.768  83.859  1.00 28.15  ? 529  PHE   C CB    1 
ATOM   2977 C CG    . PHE   A 1 529  ? 149.290 79.685  84.703  1.00 27.85  ? 529  PHE   C CG    1 
ATOM   2978 C CD1   . PHE   A 1 529  ? 148.309 79.966  85.632  1.00 26.78  ? 529  PHE   C CD1   1 
ATOM   2979 C CD2   . PHE   A 1 529  ? 149.721 78.376  84.570  1.00 29.59  ? 529  PHE   C CD2   1 
ATOM   2980 C CE1   . PHE   A 1 529  ? 147.771 78.965  86.405  1.00 32.15  ? 529  PHE   C CE1   1 
ATOM   2981 C CE2   . PHE   A 1 529  ? 149.186 77.379  85.340  1.00 31.06  ? 529  PHE   C CE2   1 
ATOM   2982 C CZ    . PHE   A 1 529  ? 148.211 77.673  86.255  1.00 35.41  ? 529  PHE   C CZ    1 
ATOM   2983 N N     . ALA   A 1 530  ? 151.962 82.950  82.805  1.00 29.27  ? 530  ALA   C N     1 
ATOM   2984 C CA    . ALA   A 1 530  ? 152.620 83.651  81.709  1.00 29.33  ? 530  ALA   C CA    1 
ATOM   2985 C C     . ALA   A 1 530  ? 154.124 83.400  81.761  1.00 29.89  ? 530  ALA   C C     1 
ATOM   2986 O O     . ALA   A 1 530  ? 154.773 83.260  80.725  1.00 33.37  ? 530  ALA   C O     1 
ATOM   2987 C CB    . ALA   A 1 530  ? 152.332 85.143  81.784  1.00 29.59  ? 530  ALA   C CB    1 
ATOM   2988 N N     . ALA   A 1 531  ? 154.687 83.313  82.964  1.00 29.82  ? 531  ALA   C N     1 
ATOM   2989 C CA    . ALA   A 1 531  ? 156.110 83.033  83.095  1.00 28.07  ? 531  ALA   C CA    1 
ATOM   2990 C C     . ALA   A 1 531  ? 156.435 81.632  82.584  1.00 31.62  ? 531  ALA   C C     1 
ATOM   2991 O O     . ALA   A 1 531  ? 157.435 81.432  81.899  1.00 35.17  ? 531  ALA   C O     1 
ATOM   2992 C CB    . ALA   A 1 531  ? 156.551 83.173  84.540  1.00 23.70  ? 531  ALA   C CB    1 
ATOM   2993 N N     . MET   A 1 532  ? 155.582 80.653  82.894  1.00 32.11  ? 532  MET   C N     1 
ATOM   2994 C CA    . MET   A 1 532  ? 155.843 79.300  82.416  1.00 34.79  ? 532  MET   C CA    1 
ATOM   2995 C C     . MET   A 1 532  ? 155.760 79.224  80.909  1.00 38.93  ? 532  MET   C C     1 
ATOM   2996 O O     . MET   A 1 532  ? 156.528 78.500  80.280  1.00 43.21  ? 532  MET   C O     1 
ATOM   2997 C CB    . MET   A 1 532  ? 154.874 78.281  83.010  1.00 36.45  ? 532  MET   C CB    1 
ATOM   2998 C CG    . MET   A 1 532  ? 155.074 77.964  84.479  1.00 37.25  ? 532  MET   C CG    1 
ATOM   2999 S SD    . MET   A 1 532  ? 153.933 76.691  85.048  1.00 40.12  ? 532  MET   C SD    1 
ATOM   3000 C CE    . MET   A 1 532  ? 154.671 75.215  84.362  1.00 52.64  ? 532  MET   C CE    1 
ATOM   3001 N N     . TYR   A 1 533  ? 154.845 79.992  80.330  1.00 38.48  ? 533  TYR   C N     1 
ATOM   3002 C CA    . TYR   A 1 533  ? 154.615 79.976  78.892  1.00 41.48  ? 533  TYR   C CA    1 
ATOM   3003 C C     . TYR   A 1 533  ? 155.909 80.041  78.091  1.00 42.93  ? 533  TYR   C C     1 
ATOM   3004 O O     . TYR   A 1 533  ? 156.096 79.287  77.138  1.00 47.42  ? 533  TYR   C O     1 
ATOM   3005 C CB    . TYR   A 1 533  ? 153.701 81.132  78.494  1.00 40.87  ? 533  TYR   C CB    1 
ATOM   3006 C CG    . TYR   A 1 533  ? 153.535 81.277  77.034  1.00 44.02  ? 533  TYR   C CG    1 
ATOM   3007 C CD1   . TYR   A 1 533  ? 152.737 80.397  76.329  1.00 49.06  ? 533  TYR   C CD1   1 
ATOM   3008 C CD2   . TYR   A 1 533  ? 154.188 82.303  76.386  1.00 41.92  ? 533  TYR   C CD2   1 
ATOM   3009 C CE1   . TYR   A 1 533  ? 152.602 80.540  74.972  1.00 54.13  ? 533  TYR   C CE1   1 
ATOM   3010 C CE2   . TYR   A 1 533  ? 154.051 82.446  75.036  1.00 47.44  ? 533  TYR   C CE2   1 
ATOM   3011 C CZ    . TYR   A 1 533  ? 153.260 81.563  74.331  1.00 53.34  ? 533  TYR   C CZ    1 
ATOM   3012 O OH    . TYR   A 1 533  ? 153.127 81.691  72.988  1.00 57.22  ? 533  TYR   C OH    1 
ATOM   3013 N N     . TYR   A 1 534  ? 156.807 80.933  78.484  1.00 40.75  ? 534  TYR   C N     1 
ATOM   3014 C CA    . TYR   A 1 534  ? 158.044 81.160  77.748  1.00 38.53  ? 534  TYR   C CA    1 
ATOM   3015 C C     . TYR   A 1 534  ? 158.982 79.963  77.795  1.00 41.31  ? 534  TYR   C C     1 
ATOM   3016 O O     . TYR   A 1 534  ? 159.903 79.860  76.984  1.00 44.98  ? 534  TYR   C O     1 
ATOM   3017 C CB    . TYR   A 1 534  ? 158.770 82.380  78.317  1.00 34.91  ? 534  TYR   C CB    1 
ATOM   3018 C CG    . TYR   A 1 534  ? 158.096 83.665  78.006  1.00 35.36  ? 534  TYR   C CG    1 
ATOM   3019 C CD1   . TYR   A 1 534  ? 157.213 84.207  78.913  1.00 37.00  ? 534  TYR   C CD1   1 
ATOM   3020 C CD2   . TYR   A 1 534  ? 158.353 84.304  76.817  1.00 41.39  ? 534  TYR   C CD2   1 
ATOM   3021 C CE1   . TYR   A 1 534  ? 156.576 85.387  78.629  1.00 38.90  ? 534  TYR   C CE1   1 
ATOM   3022 C CE2   . TYR   A 1 534  ? 157.720 85.486  76.529  1.00 40.98  ? 534  TYR   C CE2   1 
ATOM   3023 C CZ    . TYR   A 1 534  ? 156.832 86.026  77.428  1.00 39.56  ? 534  TYR   C CZ    1 
ATOM   3024 O OH    . TYR   A 1 534  ? 156.192 87.198  77.135  1.00 41.26  ? 534  TYR   C OH    1 
ATOM   3025 N N     . LEU   A 1 535  ? 158.796 79.099  78.784  1.00 42.98  ? 535  LEU   C N     1 
ATOM   3026 C CA    . LEU   A 1 535  ? 159.702 77.986  79.008  1.00 45.60  ? 535  LEU   C CA    1 
ATOM   3027 C C     . LEU   A 1 535  ? 159.137 76.627  78.582  1.00 50.95  ? 535  LEU   C C     1 
ATOM   3028 O O     . LEU   A 1 535  ? 159.821 75.610  78.717  1.00 56.53  ? 535  LEU   C O     1 
ATOM   3029 C CB    . LEU   A 1 535  ? 160.063 77.937  80.499  1.00 45.85  ? 535  LEU   C CB    1 
ATOM   3030 C CG    . LEU   A 1 535  ? 160.706 79.205  81.090  1.00 39.31  ? 535  LEU   C CG    1 
ATOM   3031 C CD1   . LEU   A 1 535  ? 160.897 79.014  82.582  1.00 37.45  ? 535  LEU   C CD1   1 
ATOM   3032 C CD2   . LEU   A 1 535  ? 162.033 79.477  80.412  1.00 48.41  ? 535  LEU   C CD2   1 
ATOM   3033 N N     . LEU   A 1 536  ? 157.896 76.597  78.093  1.00 49.99  ? 536  LEU   C N     1 
ATOM   3034 C CA    . LEU   A 1 536  ? 157.235 75.318  77.816  1.00 53.57  ? 536  LEU   C CA    1 
ATOM   3035 C C     . LEU   A 1 536  ? 157.776 74.617  76.589  1.00 61.24  ? 536  LEU   C C     1 
ATOM   3036 O O     . LEU   A 1 536  ? 158.117 75.255  75.591  1.00 61.65  ? 536  LEU   C O     1 
ATOM   3037 C CB    . LEU   A 1 536  ? 155.726 75.511  77.598  1.00 50.89  ? 536  LEU   C CB    1 
ATOM   3038 C CG    . LEU   A 1 536  ? 154.904 76.002  78.779  1.00 47.49  ? 536  LEU   C CG    1 
ATOM   3039 C CD1   . LEU   A 1 536  ? 153.506 76.272  78.310  1.00 51.99  ? 536  LEU   C CD1   1 
ATOM   3040 C CD2   . LEU   A 1 536  ? 154.896 74.963  79.888  1.00 50.86  ? 536  LEU   C CD2   1 
ATOM   3041 N N     . GLU   A 1 537  ? 157.789 73.288  76.640  1.00 65.21  ? 537  GLU   C N     1 
ATOM   3042 C CA    . GLU   A 1 537  ? 158.111 72.478  75.473  1.00 69.81  ? 537  GLU   C CA    1 
ATOM   3043 C C     . GLU   A 1 537  ? 159.462 72.862  74.896  1.00 70.70  ? 537  GLU   C C     1 
ATOM   3044 O O     . GLU   A 1 537  ? 160.211 72.008  74.422  1.00 72.88  ? 537  GLU   C O     1 
ATOM   3045 C CB    . GLU   A 1 537  ? 157.032 72.638  74.394  1.00 72.43  ? 537  GLU   C CB    1 
ATOM   3046 C CG    . GLU   A 1 537  ? 155.641 72.167  74.797  1.00 78.53  ? 537  GLU   C CG    1 
ATOM   3047 C CD    . GLU   A 1 537  ? 155.551 70.684  74.987  1.00 83.21  ? 537  GLU   C CD    1 
ATOM   3048 O OE1   . GLU   A 1 537  ? 156.406 69.987  74.498  1.00 80.61  ? 537  GLU   C OE1   1 
ATOM   3049 O OE2   . GLU   A 1 537  ? 154.620 70.244  75.620  1.00 84.99  ? 537  GLU   C OE2   1 
ATOM   3050 N N     . LEU   A 1 553  ? 149.923 83.896  71.407  1.00 60.69  ? 553  LEU   C N     1 
ATOM   3051 C CA    . LEU   A 1 553  ? 151.293 83.632  70.983  1.00 63.68  ? 553  LEU   C CA    1 
ATOM   3052 C C     . LEU   A 1 553  ? 151.982 84.900  70.469  1.00 63.16  ? 553  LEU   C C     1 
ATOM   3053 O O     . LEU   A 1 553  ? 152.508 84.911  69.358  1.00 63.04  ? 553  LEU   C O     1 
ATOM   3054 C CB    . LEU   A 1 553  ? 151.290 82.556  69.885  1.00 67.52  ? 553  LEU   C CB    1 
ATOM   3055 C CG    . LEU   A 1 553  ? 151.245 81.072  70.360  1.00 69.79  ? 553  LEU   C CG    1 
ATOM   3056 C CD1   . LEU   A 1 553  ? 150.086 80.861  71.350  1.00 69.86  ? 553  LEU   C CD1   1 
ATOM   3057 C CD2   . LEU   A 1 553  ? 151.071 80.171  69.144  1.00 70.06  ? 553  LEU   C CD2   1 
ATOM   3058 N N     . PRO   A 1 554  ? 151.995 85.973  71.275  1.00 61.14  ? 554  PRO   C N     1 
ATOM   3059 C CA    . PRO   A 1 554  ? 152.472 87.307  70.945  1.00 60.75  ? 554  PRO   C CA    1 
ATOM   3060 C C     . PRO   A 1 554  ? 153.978 87.422  70.722  1.00 59.63  ? 554  PRO   C C     1 
ATOM   3061 O O     . PRO   A 1 554  ? 154.432 88.378  70.094  1.00 60.65  ? 554  PRO   C O     1 
ATOM   3062 C CB    . PRO   A 1 554  ? 152.059 88.108  72.189  1.00 58.96  ? 554  PRO   C CB    1 
ATOM   3063 C CG    . PRO   A 1 554  ? 151.995 87.087  73.307  1.00 55.96  ? 554  PRO   C CG    1 
ATOM   3064 C CD    . PRO   A 1 554  ? 151.498 85.836  72.657  1.00 59.93  ? 554  PRO   C CD    1 
ATOM   3065 N N     . SER   A 1 555  ? 154.761 86.487  71.256  1.00 57.92  ? 555  SER   C N     1 
ATOM   3066 C CA    . SER   A 1 555  ? 156.211 86.618  71.138  1.00 57.28  ? 555  SER   C CA    1 
ATOM   3067 C C     . SER   A 1 555  ? 156.953 85.301  71.308  1.00 55.88  ? 555  SER   C C     1 
ATOM   3068 O O     . SER   A 1 555  ? 157.611 84.820  70.384  1.00 54.62  ? 555  SER   C O     1 
ATOM   3069 C CB    . SER   A 1 555  ? 156.734 87.588  72.180  1.00 54.21  ? 555  SER   C CB    1 
ATOM   3070 O OG    . SER   A 1 555  ? 156.674 87.021  73.464  1.00 53.19  ? 555  SER   C OG    1 
ATOM   3071 N N     . ARG   A 1 556  ? 156.909 84.777  72.532  1.00 54.17  ? 556  ARG   C N     1 
ATOM   3072 C CA    . ARG   A 1 556  ? 157.766 83.677  72.980  1.00 52.04  ? 556  ARG   C CA    1 
ATOM   3073 C C     . ARG   A 1 556  ? 159.225 84.103  72.922  1.00 51.70  ? 556  ARG   C C     1 
ATOM   3074 O O     . ARG   A 1 556  ? 160.109 83.310  72.596  1.00 50.81  ? 556  ARG   C O     1 
ATOM   3075 C CB    . ARG   A 1 556  ? 157.576 82.415  72.146  1.00 54.42  ? 556  ARG   C CB    1 
ATOM   3076 C CG    . ARG   A 1 556  ? 156.201 81.813  72.208  1.00 56.98  ? 556  ARG   C CG    1 
ATOM   3077 C CD    . ARG   A 1 556  ? 156.144 80.496  71.544  1.00 61.81  ? 556  ARG   C CD    1 
ATOM   3078 N NE    . ARG   A 1 556  ? 156.885 79.481  72.285  1.00 63.72  ? 556  ARG   C NE    1 
ATOM   3079 C CZ    . ARG   A 1 556  ? 157.255 78.285  71.790  1.00 70.88  ? 556  ARG   C CZ    1 
ATOM   3080 N NH1   . ARG   A 1 556  ? 156.954 77.963  70.551  1.00 74.75  ? 556  ARG   C NH1   1 
ATOM   3081 N NH2   . ARG   A 1 556  ? 157.923 77.436  72.553  1.00 65.77  ? 556  ARG   C NH2   1 
ATOM   3082 N N     . ASP   A 1 557  ? 159.465 85.364  73.266  1.00 51.42  ? 557  ASP   C N     1 
ATOM   3083 C CA    . ASP   A 1 557  ? 160.806 85.932  73.278  1.00 51.13  ? 557  ASP   C CA    1 
ATOM   3084 C C     . ASP   A 1 557  ? 161.092 86.673  74.577  1.00 49.02  ? 557  ASP   C C     1 
ATOM   3085 O O     . ASP   A 1 557  ? 160.452 87.677  74.894  1.00 49.33  ? 557  ASP   C O     1 
ATOM   3086 C CB    . ASP   A 1 557  ? 161.023 86.882  72.102  1.00 53.14  ? 557  ASP   C CB    1 
ATOM   3087 C CG    . ASP   A 1 557  ? 162.465 87.389  72.045  1.00 52.72  ? 557  ASP   C CG    1 
ATOM   3088 O OD1   . ASP   A 1 557  ? 163.238 87.019  72.912  1.00 51.47  ? 557  ASP   C OD1   1 
ATOM   3089 O OD2   . ASP   A 1 557  ? 162.783 88.139  71.155  1.00 52.82  ? 557  ASP   C OD2   1 
ATOM   3090 N N     . VAL   A 1 558  ? 162.051 86.155  75.329  1.00 45.74  ? 558  VAL   C N     1 
ATOM   3091 C CA    . VAL   A 1 558  ? 162.427 86.722  76.612  1.00 43.44  ? 558  VAL   C CA    1 
ATOM   3092 C C     . VAL   A 1 558  ? 162.937 88.149  76.473  1.00 44.98  ? 558  VAL   C C     1 
ATOM   3093 O O     . VAL   A 1 558  ? 162.709 88.976  77.357  1.00 44.68  ? 558  VAL   C O     1 
ATOM   3094 C CB    . VAL   A 1 558  ? 163.504 85.860  77.281  1.00 41.78  ? 558  VAL   C CB    1 
ATOM   3095 C CG1   . VAL   A 1 558  ? 164.044 86.567  78.528  1.00 42.39  ? 558  VAL   C CG1   1 
ATOM   3096 C CG2   . VAL   A 1 558  ? 162.906 84.512  77.638  1.00 42.31  ? 558  VAL   C CG2   1 
ATOM   3097 N N     . THR   A 1 559  ? 163.669 88.432  75.397  1.00 45.75  ? 559  THR   C N     1 
ATOM   3098 C CA    . THR   A 1 559  ? 164.227 89.764  75.226  1.00 45.95  ? 559  THR   C CA    1 
ATOM   3099 C C     . THR   A 1 559  ? 163.115 90.794  75.172  1.00 47.60  ? 559  THR   C C     1 
ATOM   3100 O O     . THR   A 1 559  ? 163.177 91.825  75.841  1.00 47.51  ? 559  THR   C O     1 
ATOM   3101 C CB    . THR   A 1 559  ? 165.076 89.856  73.945  1.00 48.19  ? 559  THR   C CB    1 
ATOM   3102 O OG1   . THR   A 1 559  ? 166.197 88.969  74.050  1.00 50.09  ? 559  THR   C OG1   1 
ATOM   3103 C CG2   . THR   A 1 559  ? 165.571 91.281  73.746  1.00 50.37  ? 559  THR   C CG2   1 
ATOM   3104 N N     . VAL   A 1 560  ? 162.080 90.491  74.401  1.00 47.57  ? 560  VAL   C N     1 
ATOM   3105 C CA    . VAL   A 1 560  ? 160.945 91.387  74.260  1.00 46.98  ? 560  VAL   C CA    1 
ATOM   3106 C C     . VAL   A 1 560  ? 160.262 91.590  75.604  1.00 45.07  ? 560  VAL   C C     1 
ATOM   3107 O O     . VAL   A 1 560  ? 159.863 92.702  75.952  1.00 43.80  ? 560  VAL   C O     1 
ATOM   3108 C CB    . VAL   A 1 560  ? 159.943 90.823  73.232  1.00 47.44  ? 560  VAL   C CB    1 
ATOM   3109 C CG1   . VAL   A 1 560  ? 158.664 91.647  73.229  1.00 49.04  ? 560  VAL   C CG1   1 
ATOM   3110 C CG2   . VAL   A 1 560  ? 160.586 90.833  71.856  1.00 47.40  ? 560  VAL   C CG2   1 
ATOM   3111 N N     . LEU   A 1 561  ? 160.126 90.508  76.363  1.00 43.26  ? 561  LEU   C N     1 
ATOM   3112 C CA    . LEU   A 1 561  ? 159.514 90.584  77.680  1.00 42.53  ? 561  LEU   C CA    1 
ATOM   3113 C C     . LEU   A 1 561  ? 160.286 91.519  78.612  1.00 41.29  ? 561  LEU   C C     1 
ATOM   3114 O O     . LEU   A 1 561  ? 159.700 92.401  79.244  1.00 40.36  ? 561  LEU   C O     1 
ATOM   3115 C CB    . LEU   A 1 561  ? 159.472 89.182  78.307  1.00 40.76  ? 561  LEU   C CB    1 
ATOM   3116 C CG    . LEU   A 1 561  ? 158.915 89.081  79.729  1.00 32.67  ? 561  LEU   C CG    1 
ATOM   3117 C CD1   . LEU   A 1 561  ? 157.432 89.416  79.727  1.00 34.69  ? 561  LEU   C CD1   1 
ATOM   3118 C CD2   . LEU   A 1 561  ? 159.173 87.689  80.251  1.00 32.14  ? 561  LEU   C CD2   1 
ATOM   3119 N N     . LEU   A 1 562  ? 161.596 91.338  78.690  1.00 40.30  ? 562  LEU   C N     1 
ATOM   3120 C CA    . LEU   A 1 562  ? 162.421 92.126  79.606  1.00 37.61  ? 562  LEU   C CA    1 
ATOM   3121 C C     . LEU   A 1 562  ? 162.436 93.608  79.234  1.00 39.54  ? 562  LEU   C C     1 
ATOM   3122 O O     . LEU   A 1 562  ? 162.446 94.474  80.112  1.00 38.83  ? 562  LEU   C O     1 
ATOM   3123 C CB    . LEU   A 1 562  ? 163.851 91.570  79.627  1.00 36.65  ? 562  LEU   C CB    1 
ATOM   3124 C CG    . LEU   A 1 562  ? 164.034 90.169  80.269  1.00 34.95  ? 562  LEU   C CG    1 
ATOM   3125 C CD1   . LEU   A 1 562  ? 165.450 89.686  80.005  1.00 37.01  ? 562  LEU   C CD1   1 
ATOM   3126 C CD2   . LEU   A 1 562  ? 163.767 90.241  81.772  1.00 32.04  ? 562  LEU   C CD2   1 
ATOM   3127 N N     . GLU   A 1 563  ? 162.406 93.899  77.939  1.00 42.80  ? 563  GLU   C N     1 
ATOM   3128 C CA    . GLU   A 1 563  ? 162.428 95.277  77.448  1.00 43.16  ? 563  GLU   C CA    1 
ATOM   3129 C C     . GLU   A 1 563  ? 161.177 96.058  77.837  1.00 40.11  ? 563  GLU   C C     1 
ATOM   3130 O O     . GLU   A 1 563  ? 161.157 97.286  77.752  1.00 39.02  ? 563  GLU   C O     1 
ATOM   3131 C CB    . GLU   A 1 563  ? 162.591 95.304  75.928  1.00 45.58  ? 563  GLU   C CB    1 
ATOM   3132 C CG    . GLU   A 1 563  ? 163.976 94.912  75.429  1.00 49.34  ? 563  GLU   C CG    1 
ATOM   3133 C CD    . GLU   A 1 563  ? 164.062 94.862  73.928  1.00 56.32  ? 563  GLU   C CD    1 
ATOM   3134 O OE1   . GLU   A 1 563  ? 163.056 95.056  73.288  1.00 54.70  ? 563  GLU   C OE1   1 
ATOM   3135 O OE2   . GLU   A 1 563  ? 165.135 94.630  73.422  1.00 58.79  ? 563  GLU   C OE2   1 
ATOM   3136 N N     . ASN   A 1 564  ? 160.122 95.350  78.230  1.00 38.48  ? 564  ASN   C N     1 
ATOM   3137 C CA    . ASN   A 1 564  ? 158.861 95.978  78.587  1.00 37.51  ? 564  ASN   C CA    1 
ATOM   3138 C C     . ASN   A 1 564  ? 158.611 95.940  80.089  1.00 34.03  ? 564  ASN   C C     1 
ATOM   3139 O O     . ASN   A 1 564  ? 157.480 96.134  80.536  1.00 31.97  ? 564  ASN   C O     1 
ATOM   3140 C CB    . ASN   A 1 564  ? 157.723 95.312  77.838  1.00 38.92  ? 564  ASN   C CB    1 
ATOM   3141 C CG    . ASN   A 1 564  ? 157.672 95.708  76.379  1.00 40.55  ? 564  ASN   C CG    1 
ATOM   3142 O OD1   . ASN   A 1 564  ? 157.030 96.710  76.034  1.00 39.83  ? 564  ASN   C OD1   1 
ATOM   3143 N ND2   . ASN   A 1 564  ? 158.327 94.966  75.521  1.00 42.77  ? 564  ASN   C ND2   1 
ATOM   3144 N N     . TYR   A 1 565  ? 159.661 95.669  80.863  1.00 31.56  ? 565  TYR   C N     1 
ATOM   3145 C CA    . TYR   A 1 565  ? 159.541 95.534  82.311  1.00 27.57  ? 565  TYR   C CA    1 
ATOM   3146 C C     . TYR   A 1 565  ? 159.035 96.803  82.993  1.00 26.12  ? 565  TYR   C C     1 
ATOM   3147 O O     . TYR   A 1 565  ? 158.020 96.790  83.683  1.00 26.33  ? 565  TYR   C O     1 
ATOM   3148 C CB    . TYR   A 1 565  ? 160.899 95.140  82.894  1.00 26.32  ? 565  TYR   C CB    1 
ATOM   3149 C CG    . TYR   A 1 565  ? 160.919 94.930  84.382  1.00 23.83  ? 565  TYR   C CG    1 
ATOM   3150 C CD1   . TYR   A 1 565  ? 160.559 93.705  84.904  1.00 20.85  ? 565  TYR   C CD1   1 
ATOM   3151 C CD2   . TYR   A 1 565  ? 161.305 95.954  85.224  1.00 27.30  ? 565  TYR   C CD2   1 
ATOM   3152 C CE1   . TYR   A 1 565  ? 160.589 93.498  86.262  1.00 19.20  ? 565  TYR   C CE1   1 
ATOM   3153 C CE2   . TYR   A 1 565  ? 161.330 95.750  86.582  1.00 25.08  ? 565  TYR   C CE2   1 
ATOM   3154 C CZ    . TYR   A 1 565  ? 160.978 94.529  87.100  1.00 18.15  ? 565  TYR   C CZ    1 
ATOM   3155 O OH    . TYR   A 1 565  ? 161.015 94.338  88.452  1.00 18.80  ? 565  TYR   C OH    1 
ATOM   3156 N N     . GLY   A 1 566  ? 159.732 97.912  82.800  1.00 29.82  ? 566  GLY   C N     1 
ATOM   3157 C CA    . GLY   A 1 566  ? 159.371 99.147  83.493  1.00 33.34  ? 566  GLY   C CA    1 
ATOM   3158 C C     . GLY   A 1 566  ? 158.260 99.909  82.781  1.00 37.17  ? 566  GLY   C C     1 
ATOM   3159 O O     . GLY   A 1 566  ? 158.436 101.067 82.402  1.00 40.48  ? 566  GLY   C O     1 
ATOM   3160 N N     . LYS   A 1 567  ? 157.126 99.252  82.566  1.00 31.04  ? 567  LYS   C N     1 
ATOM   3161 C CA    . LYS   A 1 567  ? 156.032 99.890  81.847  1.00 28.31  ? 567  LYS   C CA    1 
ATOM   3162 C C     . LYS   A 1 567  ? 154.662 99.568  82.431  1.00 28.26  ? 567  LYS   C C     1 
ATOM   3163 O O     . LYS   A 1 567  ? 154.294 98.403  82.594  1.00 27.99  ? 567  LYS   C O     1 
ATOM   3164 C CB    . LYS   A 1 567  ? 156.062 99.490  80.371  1.00 31.92  ? 567  LYS   C CB    1 
ATOM   3165 C CG    . LYS   A 1 567  ? 157.305 99.947  79.617  1.00 36.04  ? 567  LYS   C CG    1 
ATOM   3166 C CD    . LYS   A 1 567  ? 157.173 99.694  78.125  1.00 37.64  ? 567  LYS   C CD    1 
ATOM   3167 C CE    . LYS   A 1 567  ? 158.429 100.125 77.377  1.00 41.74  ? 567  LYS   C CE    1 
ATOM   3168 N NZ    . LYS   A 1 567  ? 158.273 99.989  75.901  1.00 45.60  ? 567  LYS   C NZ    1 
ATOM   3169 N N     . PHE   A 1 568  ? 153.886 100.620 82.677  1.00 26.48  ? 568  PHE   C N     1 
ATOM   3170 C CA    . PHE   A 1 568  ? 152.516 100.505 83.165  1.00 25.32  ? 568  PHE   C CA    1 
ATOM   3171 C C     . PHE   A 1 568  ? 151.665 99.689  82.211  1.00 26.43  ? 568  PHE   C C     1 
ATOM   3172 O O     . PHE   A 1 568  ? 150.865 98.850  82.626  1.00 28.53  ? 568  PHE   C O     1 
ATOM   3173 C CB    . PHE   A 1 568  ? 151.888 101.886 83.326  1.00 25.07  ? 568  PHE   C CB    1 
ATOM   3174 C CG    . PHE   A 1 568  ? 150.448 101.869 83.782  1.00 24.82  ? 568  PHE   C CG    1 
ATOM   3175 C CD1   . PHE   A 1 568  ? 150.130 101.805 85.128  1.00 25.02  ? 568  PHE   C CD1   1 
ATOM   3176 C CD2   . PHE   A 1 568  ? 149.413 101.918 82.864  1.00 29.15  ? 568  PHE   C CD2   1 
ATOM   3177 C CE1   . PHE   A 1 568  ? 148.817 101.794 85.547  1.00 19.88  ? 568  PHE   C CE1   1 
ATOM   3178 C CE2   . PHE   A 1 568  ? 148.099 101.904 83.281  1.00 26.49  ? 568  PHE   C CE2   1 
ATOM   3179 C CZ    . PHE   A 1 568  ? 147.801 101.843 84.624  1.00 20.41  ? 568  PHE   C CZ    1 
ATOM   3180 N N     . GLU   A 1 569  ? 151.835 99.958  80.926  1.00 27.04  ? 569  GLU   C N     1 
ATOM   3181 C CA    . GLU   A 1 569  ? 151.019 99.381  79.868  1.00 29.61  ? 569  GLU   C CA    1 
ATOM   3182 C C     . GLU   A 1 569  ? 151.049 97.857  79.818  1.00 31.36  ? 569  GLU   C C     1 
ATOM   3183 O O     . GLU   A 1 569  ? 150.177 97.250  79.199  1.00 32.93  ? 569  GLU   C O     1 
ATOM   3184 C CB    . GLU   A 1 569  ? 151.469 99.942  78.517  1.00 30.19  ? 569  GLU   C CB    1 
ATOM   3185 C CG    . GLU   A 1 569  ? 151.246 101.439 78.361  1.00 34.35  ? 569  GLU   C CG    1 
ATOM   3186 C CD    . GLU   A 1 569  ? 152.315 102.271 79.018  1.00 35.98  ? 569  GLU   C CD    1 
ATOM   3187 O OE1   . GLU   A 1 569  ? 153.253 101.703 79.525  1.00 36.06  ? 569  GLU   C OE1   1 
ATOM   3188 O OE2   . GLU   A 1 569  ? 152.192 103.472 79.028  1.00 38.32  ? 569  GLU   C OE2   1 
ATOM   3189 N N     . LYS   A 1 570  ? 152.062 97.234  80.420  1.00 29.38  ? 570  LYS   C N     1 
ATOM   3190 C CA    . LYS   A 1 570  ? 152.146 95.777  80.412  1.00 27.14  ? 570  LYS   C CA    1 
ATOM   3191 C C     . LYS   A 1 570  ? 151.972 95.205  81.815  1.00 26.03  ? 570  LYS   C C     1 
ATOM   3192 O O     . LYS   A 1 570  ? 152.161 94.010  82.037  1.00 26.40  ? 570  LYS   C O     1 
ATOM   3193 C CB    . LYS   A 1 570  ? 153.466 95.318  79.793  1.00 28.19  ? 570  LYS   C CB    1 
ATOM   3194 C CG    . LYS   A 1 570  ? 153.678 95.782  78.341  1.00 33.86  ? 570  LYS   C CG    1 
ATOM   3195 C CD    . LYS   A 1 570  ? 152.610 95.217  77.403  1.00 35.13  ? 570  LYS   C CD    1 
ATOM   3196 C CE    . LYS   A 1 570  ? 152.873 95.582  75.946  1.00 39.77  ? 570  LYS   C CE    1 
ATOM   3197 N NZ    . LYS   A 1 570  ? 152.652 97.030  75.682  1.00 39.73  ? 570  LYS   C NZ    1 
ATOM   3198 N N     . GLY   A 1 571  ? 151.610 96.065  82.766  1.00 25.41  ? 571  GLY   C N     1 
ATOM   3199 C CA    . GLY   A 1 571  ? 151.397 95.651  84.147  1.00 22.58  ? 571  GLY   C CA    1 
ATOM   3200 C C     . GLY   A 1 571  ? 152.691 95.523  84.948  1.00 21.61  ? 571  GLY   C C     1 
ATOM   3201 O O     . GLY   A 1 571  ? 152.738 94.793  85.938  1.00 23.78  ? 571  GLY   C O     1 
ATOM   3202 N N     . TYR   A 1 572  ? 153.748 96.196  84.499  1.00 21.57  ? 572  TYR   C N     1 
ATOM   3203 C CA    . TYR   A 1 572  ? 155.063 96.174  85.144  1.00 19.10  ? 572  TYR   C CA    1 
ATOM   3204 C C     . TYR   A 1 572  ? 155.785 94.821  85.067  1.00 19.02  ? 572  TYR   C C     1 
ATOM   3205 O O     . TYR   A 1 572  ? 157.009 94.766  85.150  1.00 20.86  ? 572  TYR   C O     1 
ATOM   3206 C CB    . TYR   A 1 572  ? 154.959 96.653  86.591  1.00 18.54  ? 572  TYR   C CB    1 
ATOM   3207 C CG    . TYR   A 1 572  ? 154.428 98.057  86.713  1.00 18.05  ? 572  TYR   C CG    1 
ATOM   3208 C CD1   . TYR   A 1 572  ? 153.171 98.291  87.241  1.00 16.51  ? 572  TYR   C CD1   1 
ATOM   3209 C CD2   . TYR   A 1 572  ? 155.206 99.116  86.285  1.00 25.72  ? 572  TYR   C CD2   1 
ATOM   3210 C CE1   . TYR   A 1 572  ? 152.702 99.585  87.348  1.00 17.95  ? 572  TYR   C CE1   1 
ATOM   3211 C CE2   . TYR   A 1 572  ? 154.738 100.405 86.391  1.00 27.24  ? 572  TYR   C CE2   1 
ATOM   3212 C CZ    . TYR   A 1 572  ? 153.495 100.642 86.920  1.00 19.58  ? 572  TYR   C CZ    1 
ATOM   3213 O OH    . TYR   A 1 572  ? 153.038 101.930 87.022  1.00 19.52  ? 572  TYR   C OH    1 
ATOM   3214 N N     . LEU   A 1 573  ? 155.048 93.731  84.914  1.00 16.61  ? 573  LEU   C N     1 
ATOM   3215 C CA    . LEU   A 1 573  ? 155.661 92.422  84.718  1.00 14.55  ? 573  LEU   C CA    1 
ATOM   3216 C C     . LEU   A 1 573  ? 156.644 92.055  85.824  1.00 16.55  ? 573  LEU   C C     1 
ATOM   3217 O O     . LEU   A 1 573  ? 157.624 91.348  85.578  1.00 19.25  ? 573  LEU   C O     1 
ATOM   3218 C CB    . LEU   A 1 573  ? 156.412 92.408  83.380  1.00 17.63  ? 573  LEU   C CB    1 
ATOM   3219 C CG    . LEU   A 1 573  ? 155.602 92.792  82.140  1.00 23.13  ? 573  LEU   C CG    1 
ATOM   3220 C CD1   . LEU   A 1 573  ? 156.540 92.914  80.958  1.00 25.99  ? 573  LEU   C CD1   1 
ATOM   3221 C CD2   . LEU   A 1 573  ? 154.554 91.738  81.872  1.00 27.99  ? 573  LEU   C CD2   1 
ATOM   3222 N N     . ILE   A 1 574  ? 156.395 92.519  87.043  1.00 14.92  ? 574  ILE   C N     1 
ATOM   3223 C CA    . ILE   A 1 574  ? 157.321 92.253  88.134  1.00 12.52  ? 574  ILE   C CA    1 
ATOM   3224 C C     . ILE   A 1 574  ? 157.338 90.783  88.497  1.00 13.77  ? 574  ILE   C C     1 
ATOM   3225 O O     . ILE   A 1 574  ? 158.403 90.180  88.630  1.00 16.54  ? 574  ILE   C O     1 
ATOM   3226 C CB    . ILE   A 1 574  ? 156.983 93.103  89.369  1.00 10.24  ? 574  ILE   C CB    1 
ATOM   3227 C CG1   . ILE   A 1 574  ? 157.259 94.575  89.052  1.00 13.24  ? 574  ILE   C CG1   1 
ATOM   3228 C CG2   . ILE   A 1 574  ? 157.809 92.636  90.572  1.00 11.50  ? 574  ILE   C CG2   1 
ATOM   3229 C CD1   . ILE   A 1 574  ? 156.675 95.548  90.047  1.00 12.76  ? 574  ILE   C CD1   1 
ATOM   3230 N N     . PHE   A 1 575  ? 156.158 90.198  88.646  1.00 12.62  ? 575  PHE   C N     1 
ATOM   3231 C CA    . PHE   A 1 575  ? 156.068 88.796  89.010  1.00 10.93  ? 575  PHE   C CA    1 
ATOM   3232 C C     . PHE   A 1 575  ? 156.397 87.885  87.843  1.00 15.51  ? 575  PHE   C C     1 
ATOM   3233 O O     . PHE   A 1 575  ? 156.900 86.784  88.041  1.00 19.32  ? 575  PHE   C O     1 
ATOM   3234 C CB    . PHE   A 1 575  ? 154.696 88.468  89.568  1.00 10.97  ? 575  PHE   C CB    1 
ATOM   3235 C CG    . PHE   A 1 575  ? 154.514 88.926  90.971  1.00 10.11  ? 575  PHE   C CG    1 
ATOM   3236 C CD1   . PHE   A 1 575  ? 153.937 90.147  91.244  1.00 9.92   ? 575  PHE   C CD1   1 
ATOM   3237 C CD2   . PHE   A 1 575  ? 154.919 88.133  92.026  1.00 9.83   ? 575  PHE   C CD2   1 
ATOM   3238 C CE1   . PHE   A 1 575  ? 153.773 90.572  92.538  1.00 8.32   ? 575  PHE   C CE1   1 
ATOM   3239 C CE2   . PHE   A 1 575  ? 154.753 88.555  93.321  1.00 11.09  ? 575  PHE   C CE2   1 
ATOM   3240 C CZ    . PHE   A 1 575  ? 154.180 89.778  93.574  1.00 10.26  ? 575  PHE   C CZ    1 
ATOM   3241 N N     . VAL   A 1 576  ? 156.137 88.331  86.621  1.00 16.71  ? 576  VAL   C N     1 
ATOM   3242 C CA    . VAL   A 1 576  ? 156.427 87.469  85.485  1.00 15.06  ? 576  VAL   C CA    1 
ATOM   3243 C C     . VAL   A 1 576  ? 157.924 87.207  85.412  1.00 18.90  ? 576  VAL   C C     1 
ATOM   3244 O O     . VAL   A 1 576  ? 158.353 86.064  85.248  1.00 20.73  ? 576  VAL   C O     1 
ATOM   3245 C CB    . VAL   A 1 576  ? 155.958 88.101  84.163  1.00 15.22  ? 576  VAL   C CB    1 
ATOM   3246 C CG1   . VAL   A 1 576  ? 156.429 87.249  82.996  1.00 21.18  ? 576  VAL   C CG1   1 
ATOM   3247 C CG2   . VAL   A 1 576  ? 154.451 88.215  84.154  1.00 20.61  ? 576  VAL   C CG2   1 
ATOM   3248 N N     . VAL   A 1 577  ? 158.723 88.262  85.549  1.00 18.74  ? 577  VAL   C N     1 
ATOM   3249 C CA    . VAL   A 1 577  ? 160.170 88.105  85.516  1.00 17.31  ? 577  VAL   C CA    1 
ATOM   3250 C C     . VAL   A 1 577  ? 160.676 87.395  86.763  1.00 19.31  ? 577  VAL   C C     1 
ATOM   3251 O O     . VAL   A 1 577  ? 161.556 86.537  86.678  1.00 20.90  ? 577  VAL   C O     1 
ATOM   3252 C CB    . VAL   A 1 577  ? 160.873 89.461  85.338  1.00 16.04  ? 577  VAL   C CB    1 
ATOM   3253 C CG1   . VAL   A 1 577  ? 162.381 89.292  85.487  1.00 18.84  ? 577  VAL   C CG1   1 
ATOM   3254 C CG2   . VAL   A 1 577  ? 160.539 90.011  83.956  1.00 19.84  ? 577  VAL   C CG2   1 
ATOM   3255 N N     . ARG   A 1 578  ? 160.134 87.752  87.923  1.00 17.92  ? 578  ARG   C N     1 
ATOM   3256 C CA    . ARG   A 1 578  ? 160.550 87.113  89.161  1.00 14.84  ? 578  ARG   C CA    1 
ATOM   3257 C C     . ARG   A 1 578  ? 160.311 85.606  89.114  1.00 17.54  ? 578  ARG   C C     1 
ATOM   3258 O O     . ARG   A 1 578  ? 161.167 84.826  89.537  1.00 19.55  ? 578  ARG   C O     1 
ATOM   3259 C CB    . ARG   A 1 578  ? 159.811 87.704  90.343  1.00 10.68  ? 578  ARG   C CB    1 
ATOM   3260 C CG    . ARG   A 1 578  ? 160.240 87.165  91.676  1.00 12.03  ? 578  ARG   C CG    1 
ATOM   3261 C CD    . ARG   A 1 578  ? 159.485 87.768  92.780  1.00 10.16  ? 578  ARG   C CD    1 
ATOM   3262 N NE    . ARG   A 1 578  ? 159.701 89.200  92.865  1.00 9.41   ? 578  ARG   C NE    1 
ATOM   3263 C CZ    . ARG   A 1 578  ? 158.954 90.032  93.603  1.00 8.27   ? 578  ARG   C CZ    1 
ATOM   3264 N NH1   . ARG   A 1 578  ? 157.961 89.564  94.311  1.00 9.85   ? 578  ARG   C NH1   1 
ATOM   3265 N NH2   . ARG   A 1 578  ? 159.214 91.322  93.619  1.00 9.03   ? 578  ARG   C NH2   1 
ATOM   3266 N N     . PHE   A 1 579  ? 159.161 85.190  88.587  1.00 18.10  ? 579  PHE   C N     1 
ATOM   3267 C CA    . PHE   A 1 579  ? 158.861 83.769  88.493  1.00 18.71  ? 579  PHE   C CA    1 
ATOM   3268 C C     . PHE   A 1 579  ? 159.795 83.077  87.514  1.00 21.81  ? 579  PHE   C C     1 
ATOM   3269 O O     . PHE   A 1 579  ? 160.219 81.949  87.761  1.00 28.09  ? 579  PHE   C O     1 
ATOM   3270 C CB    . PHE   A 1 579  ? 157.404 83.524  88.100  1.00 17.32  ? 579  PHE   C CB    1 
ATOM   3271 C CG    . PHE   A 1 579  ? 156.414 83.669  89.244  1.00 17.20  ? 579  PHE   C CG    1 
ATOM   3272 C CD1   . PHE   A 1 579  ? 155.331 84.529  89.150  1.00 17.70  ? 579  PHE   C CD1   1 
ATOM   3273 C CD2   . PHE   A 1 579  ? 156.566 82.939  90.412  1.00 18.53  ? 579  PHE   C CD2   1 
ATOM   3274 C CE1   . PHE   A 1 579  ? 154.430 84.653  90.191  1.00 17.43  ? 579  PHE   C CE1   1 
ATOM   3275 C CE2   . PHE   A 1 579  ? 155.667 83.065  91.451  1.00 19.43  ? 579  PHE   C CE2   1 
ATOM   3276 C CZ    . PHE   A 1 579  ? 154.599 83.921  91.338  1.00 17.41  ? 579  PHE   C CZ    1 
ATOM   3277 N N     . LEU   A 1 580  ? 160.165 83.750  86.425  1.00 22.34  ? 580  LEU   C N     1 
ATOM   3278 C CA    . LEU   A 1 580  ? 161.112 83.145  85.495  1.00 23.22  ? 580  LEU   C CA    1 
ATOM   3279 C C     . LEU   A 1 580  ? 162.428 82.842  86.194  1.00 27.36  ? 580  LEU   C C     1 
ATOM   3280 O O     . LEU   A 1 580  ? 163.023 81.791  85.975  1.00 31.47  ? 580  LEU   C O     1 
ATOM   3281 C CB    . LEU   A 1 580  ? 161.369 84.058  84.288  1.00 21.59  ? 580  LEU   C CB    1 
ATOM   3282 C CG    . LEU   A 1 580  ? 160.227 84.181  83.274  1.00 25.63  ? 580  LEU   C CG    1 
ATOM   3283 C CD1   . LEU   A 1 580  ? 160.525 85.314  82.316  1.00 24.17  ? 580  LEU   C CD1   1 
ATOM   3284 C CD2   . LEU   A 1 580  ? 160.072 82.871  82.507  1.00 33.86  ? 580  LEU   C CD2   1 
ATOM   3285 N N     . PHE   A 1 581  ? 162.877 83.730  87.075  1.00 24.55  ? 581  PHE   C N     1 
ATOM   3286 C CA    . PHE   A 1 581  ? 164.112 83.446  87.795  1.00 23.65  ? 581  PHE   C CA    1 
ATOM   3287 C C     . PHE   A 1 581  ? 163.996 82.162  88.609  1.00 28.09  ? 581  PHE   C C     1 
ATOM   3288 O O     . PHE   A 1 581  ? 164.914 81.349  88.621  1.00 32.70  ? 581  PHE   C O     1 
ATOM   3289 C CB    . PHE   A 1 581  ? 164.492 84.596  88.726  1.00 21.26  ? 581  PHE   C CB    1 
ATOM   3290 C CG    . PHE   A 1 581  ? 165.293 85.666  88.075  1.00 21.47  ? 581  PHE   C CG    1 
ATOM   3291 C CD1   . PHE   A 1 581  ? 164.705 86.831  87.627  1.00 24.32  ? 581  PHE   C CD1   1 
ATOM   3292 C CD2   . PHE   A 1 581  ? 166.649 85.508  87.917  1.00 24.30  ? 581  PHE   C CD2   1 
ATOM   3293 C CE1   . PHE   A 1 581  ? 165.462 87.815  87.036  1.00 24.28  ? 581  PHE   C CE1   1 
ATOM   3294 C CE2   . PHE   A 1 581  ? 167.402 86.484  87.327  1.00 27.90  ? 581  PHE   C CE2   1 
ATOM   3295 C CZ    . PHE   A 1 581  ? 166.809 87.641  86.886  1.00 24.76  ? 581  PHE   C CZ    1 
ATOM   3296 N N     . GLY   A 1 582  ? 162.860 81.980  89.276  1.00 27.62  ? 582  GLY   C N     1 
ATOM   3297 C CA    . GLY   A 1 582  ? 162.627 80.779  90.080  1.00 27.19  ? 582  GLY   C CA    1 
ATOM   3298 C C     . GLY   A 1 582  ? 162.456 79.517  89.229  1.00 28.31  ? 582  GLY   C C     1 
ATOM   3299 O O     . GLY   A 1 582  ? 162.966 78.450  89.574  1.00 34.37  ? 582  GLY   C O     1 
ATOM   3300 N N     . LEU   A 1 583  ? 161.721 79.642  88.126  1.00 28.63  ? 583  LEU   C N     1 
ATOM   3301 C CA    . LEU   A 1 583  ? 161.430 78.509  87.250  1.00 31.03  ? 583  LEU   C CA    1 
ATOM   3302 C C     . LEU   A 1 583  ? 162.677 78.012  86.530  1.00 36.95  ? 583  LEU   C C     1 
ATOM   3303 O O     . LEU   A 1 583  ? 162.842 76.812  86.300  1.00 44.48  ? 583  LEU   C O     1 
ATOM   3304 C CB    . LEU   A 1 583  ? 160.371 78.907  86.212  1.00 29.41  ? 583  LEU   C CB    1 
ATOM   3305 C CG    . LEU   A 1 583  ? 158.936 79.151  86.736  1.00 25.99  ? 583  LEU   C CG    1 
ATOM   3306 C CD1   . LEU   A 1 583  ? 158.118 79.819  85.640  1.00 28.73  ? 583  LEU   C CD1   1 
ATOM   3307 C CD2   . LEU   A 1 583  ? 158.298 77.825  87.135  1.00 26.55  ? 583  LEU   C CD2   1 
ATOM   3308 N N     . VAL   A 1 584  ? 163.559 78.933  86.170  1.00 34.52  ? 584  VAL   C N     1 
ATOM   3309 C CA    . VAL   A 1 584  ? 164.773 78.571  85.459  1.00 37.59  ? 584  VAL   C CA    1 
ATOM   3310 C C     . VAL   A 1 584  ? 165.843 78.085  86.417  1.00 43.49  ? 584  VAL   C C     1 
ATOM   3311 O O     . VAL   A 1 584  ? 166.674 78.860  86.882  1.00 45.48  ? 584  VAL   C O     1 
ATOM   3312 C CB    . VAL   A 1 584  ? 165.301 79.786  84.680  1.00 34.46  ? 584  VAL   C CB    1 
ATOM   3313 C CG1   . VAL   A 1 584  ? 166.596 79.442  83.945  1.00 46.26  ? 584  VAL   C CG1   1 
ATOM   3314 C CG2   . VAL   A 1 584  ? 164.256 80.223  83.684  1.00 40.31  ? 584  VAL   C CG2   1 
ATOM   3315 N N     . ASN   A 1 585  ? 165.836 76.787  86.682  1.00 50.05  ? 585  ASN   C N     1 
ATOM   3316 C CA    . ASN   A 1 585  ? 166.781 76.192  87.619  1.00 54.05  ? 585  ASN   C CA    1 
ATOM   3317 C C     . ASN   A 1 585  ? 167.244 74.836  87.103  1.00 61.39  ? 585  ASN   C C     1 
ATOM   3318 O O     . ASN   A 1 585  ? 166.796 74.376  86.051  1.00 63.24  ? 585  ASN   C O     1 
ATOM   3319 C CB    . ASN   A 1 585  ? 166.137 76.065  88.997  1.00 52.15  ? 585  ASN   C CB    1 
ATOM   3320 C CG    . ASN   A 1 585  ? 167.127 76.054  90.159  1.00 54.85  ? 585  ASN   C CG    1 
ATOM   3321 O OD1   . ASN   A 1 585  ? 168.131 75.326  90.154  1.00 62.93  ? 585  ASN   C OD1   1 
ATOM   3322 N ND2   . ASN   A 1 585  ? 166.847 76.848  91.157  1.00 40.89  ? 585  ASN   C ND2   1 
ATOM   3323 N N     . GLN   A 1 586  ? 168.131 74.195  87.852  1.00 65.46  ? 586  GLN   C N     1 
ATOM   3324 C CA    . GLN   A 1 586  ? 168.618 72.870  87.510  1.00 69.78  ? 586  GLN   C CA    1 
ATOM   3325 C C     . GLN   A 1 586  ? 168.053 71.843  88.478  1.00 73.14  ? 586  GLN   C C     1 
ATOM   3326 O O     . GLN   A 1 586  ? 167.853 70.680  88.126  1.00 75.58  ? 586  GLN   C O     1 
ATOM   3327 C CB    . GLN   A 1 586  ? 170.147 72.836  87.541  1.00 72.59  ? 586  GLN   C CB    1 
ATOM   3328 C CG    . GLN   A 1 586  ? 170.798 73.756  86.529  1.00 70.78  ? 586  GLN   C CG    1 
ATOM   3329 C CD    . GLN   A 1 586  ? 172.316 73.712  86.586  1.00 73.71  ? 586  GLN   C CD    1 
ATOM   3330 O OE1   . GLN   A 1 586  ? 172.951 72.861  85.954  1.00 80.06  ? 586  GLN   C OE1   1 
ATOM   3331 N NE2   . GLN   A 1 586  ? 172.904 74.627  87.346  1.00 71.61  ? 586  GLN   C NE2   1 
ATOM   3332 N N     . GLU   A 1 587  ? 167.785 72.282  89.703  1.00 75.48  ? 587  GLU   C N     1 
ATOM   3333 C CA    . GLU   A 1 587  ? 167.287 71.379  90.734  1.00 78.79  ? 587  GLU   C CA    1 
ATOM   3334 C C     . GLU   A 1 587  ? 165.777 71.261  90.650  1.00 79.13  ? 587  GLU   C C     1 
ATOM   3335 O O     . GLU   A 1 587  ? 165.053 71.683  91.552  1.00 79.73  ? 587  GLU   C O     1 
ATOM   3336 C CB    . GLU   A 1 587  ? 167.708 71.860  92.124  1.00 81.55  ? 587  GLU   C CB    1 
ATOM   3337 C CG    . GLU   A 1 587  ? 169.212 71.869  92.346  1.00 85.25  ? 587  GLU   C CG    1 
ATOM   3338 C CD    . GLU   A 1 587  ? 169.602 72.235  93.752  1.00 87.28  ? 587  GLU   C CD    1 
ATOM   3339 O OE1   . GLU   A 1 587  ? 168.730 72.479  94.551  1.00 90.48  ? 587  GLU   C OE1   1 
ATOM   3340 O OE2   . GLU   A 1 587  ? 170.779 72.267  94.028  1.00 91.20  ? 587  GLU   C OE2   1 
ATOM   3341 N N     . ARG   A 1 588  ? 165.312 70.697  89.547  1.00 83.65  ? 588  ARG   C N     1 
ATOM   3342 C CA    . ARG   A 1 588  ? 163.889 70.566  89.278  1.00 82.03  ? 588  ARG   C CA    1 
ATOM   3343 C C     . ARG   A 1 588  ? 163.435 69.127  89.447  1.00 86.65  ? 588  ARG   C C     1 
ATOM   3344 O O     . ARG   A 1 588  ? 164.226 68.194  89.313  1.00 85.82  ? 588  ARG   C O     1 
ATOM   3345 C CB    . ARG   A 1 588  ? 163.565 71.069  87.881  1.00 79.94  ? 588  ARG   C CB    1 
ATOM   3346 C CG    . ARG   A 1 588  ? 163.722 72.575  87.716  1.00 74.53  ? 588  ARG   C CG    1 
ATOM   3347 C CD    . ARG   A 1 588  ? 163.421 73.046  86.330  1.00 75.83  ? 588  ARG   C CD    1 
ATOM   3348 N NE    . ARG   A 1 588  ? 164.465 72.655  85.382  1.00 74.08  ? 588  ARG   C NE    1 
ATOM   3349 C CZ    . ARG   A 1 588  ? 164.333 71.750  84.378  1.00 79.68  ? 588  ARG   C CZ    1 
ATOM   3350 N NH1   . ARG   A 1 588  ? 163.184 71.136  84.154  1.00 83.20  ? 588  ARG   C NH1   1 
ATOM   3351 N NH2   . ARG   A 1 588  ? 165.373 71.480  83.605  1.00 75.93  ? 588  ARG   C NH2   1 
ATOM   3352 N N     . THR   A 1 589  ? 162.156 68.959  89.748  1.00 85.94  ? 589  THR   C N     1 
ATOM   3353 C CA    . THR   A 1 589  ? 161.577 67.638  89.952  1.00 91.06  ? 589  THR   C CA    1 
ATOM   3354 C C     . THR   A 1 589  ? 160.371 67.414  89.056  1.00 97.72  ? 589  THR   C C     1 
ATOM   3355 O O     . THR   A 1 589  ? 160.149 68.157  88.101  1.00 79.59  ? 589  THR   C O     1 
ATOM   3356 C CB    . THR   A 1 589  ? 161.195 67.420  91.431  1.00 99.42  ? 589  THR   C CB    1 
ATOM   3357 O OG1   . THR   A 1 589  ? 160.824 66.045  91.625  1.00 90.56  ? 589  THR   C OG1   1 
ATOM   3358 C CG2   . THR   A 1 589  ? 160.041 68.334  91.836  1.00 86.89  ? 589  THR   C CG2   1 
ATOM   3359 N N     . SER   A 1 590  ? 159.628 66.354  89.337  1.00 93.17  ? 590  SER   C N     1 
ATOM   3360 C CA    . SER   A 1 590  ? 158.451 66.014  88.552  1.00 98.85  ? 590  SER   C CA    1 
ATOM   3361 C C     . SER   A 1 590  ? 157.273 66.919  88.893  1.00 86.45  ? 590  SER   C C     1 
ATOM   3362 O O     . SER   A 1 590  ? 157.301 67.637  89.890  1.00 88.40  ? 590  SER   C O     1 
ATOM   3363 C CB    . SER   A 1 590  ? 158.075 64.563  88.773  1.00 84.02  ? 590  SER   C CB    1 
ATOM   3364 O OG    . SER   A 1 590  ? 157.662 64.345  90.092  1.00 98.91  ? 590  SER   C OG    1 
ATOM   3365 N N     . TYR   A 1 591  ? 156.241 66.869  88.053  1.00 90.30  ? 591  TYR   C N     1 
ATOM   3366 C CA    . TYR   A 1 591  ? 155.018 67.659  88.204  1.00 89.18  ? 591  TYR   C CA    1 
ATOM   3367 C C     . TYR   A 1 591  ? 155.230 69.112  87.773  1.00 82.44  ? 591  TYR   C C     1 
ATOM   3368 O O     . TYR   A 1 591  ? 155.685 69.946  88.555  1.00 79.21  ? 591  TYR   C O     1 
ATOM   3369 C CB    . TYR   A 1 591  ? 154.498 67.629  89.646  1.00 91.74  ? 591  TYR   C CB    1 
ATOM   3370 C CG    . TYR   A 1 591  ? 154.371 66.244  90.246  1.00 87.14  ? 591  TYR   C CG    1 
ATOM   3371 C CD1   . TYR   A 1 591  ? 155.132 65.901  91.355  1.00 93.27  ? 591  TYR   C CD1   1 
ATOM   3372 C CD2   . TYR   A 1 591  ? 153.518 65.321  89.687  1.00 90.17  ? 591  TYR   C CD2   1 
ATOM   3373 C CE1   . TYR   A 1 591  ? 155.025 64.639  91.903  1.00 97.77  ? 591  TYR   C CE1   1 
ATOM   3374 C CE2   . TYR   A 1 591  ? 153.411 64.057  90.233  1.00 95.82  ? 591  TYR   C CE2   1 
ATOM   3375 C CZ    . TYR   A 1 591  ? 154.162 63.716  91.335  1.00 96.89  ? 591  TYR   C CZ    1 
ATOM   3376 O OH    . TYR   A 1 591  ? 154.053 62.458  91.882  1.00 97.45  ? 591  TYR   C OH    1 
ATOM   3377 N N     . LEU   A 1 592  ? 154.898 69.403  86.513  1.00 82.35  ? 592  LEU   C N     1 
ATOM   3378 C CA    . LEU   A 1 592  ? 154.981 70.744  85.913  1.00 81.01  ? 592  LEU   C CA    1 
ATOM   3379 C C     . LEU   A 1 592  ? 156.418 71.203  85.643  1.00 81.01  ? 592  LEU   C C     1 
ATOM   3380 O O     . LEU   A 1 592  ? 156.740 71.658  84.546  1.00 78.45  ? 592  LEU   C O     1 
ATOM   3381 C CB    . LEU   A 1 592  ? 154.276 71.782  86.807  1.00 69.40  ? 592  LEU   C CB    1 
ATOM   3382 C CG    . LEU   A 1 592  ? 152.761 71.569  87.041  1.00 66.28  ? 592  LEU   C CG    1 
ATOM   3383 C CD1   . LEU   A 1 592  ? 152.266 72.557  88.090  1.00 56.65  ? 592  LEU   C CD1   1 
ATOM   3384 C CD2   . LEU   A 1 592  ? 152.006 71.761  85.737  1.00 72.70  ? 592  LEU   C CD2   1 
ATOM   3385 N N     . GLU   A 1 593  ? 157.284 71.095  86.642  1.00 83.51  ? 593  GLU   C N     1 
ATOM   3386 C CA    . GLU   A 1 593  ? 158.660 71.567  86.523  1.00 83.33  ? 593  GLU   C CA    1 
ATOM   3387 C C     . GLU   A 1 593  ? 159.460 70.826  85.455  1.00 80.99  ? 593  GLU   C C     1 
ATOM   3388 O O     . GLU   A 1 593  ? 160.393 71.384  84.874  1.00 80.76  ? 593  GLU   C O     1 
ATOM   3389 C CB    . GLU   A 1 593  ? 159.386 71.454  87.865  1.00 84.32  ? 593  GLU   C CB    1 
ATOM   3390 C CG    . GLU   A 1 593  ? 158.918 72.430  88.923  1.00 81.81  ? 593  GLU   C CG    1 
ATOM   3391 C CD    . GLU   A 1 593  ? 159.739 72.358  90.186  1.00 81.52  ? 593  GLU   C CD    1 
ATOM   3392 O OE1   . GLU   A 1 593  ? 160.576 71.483  90.294  1.00 85.87  ? 593  GLU   C OE1   1 
ATOM   3393 O OE2   . GLU   A 1 593  ? 159.536 73.187  91.043  1.00 72.26  ? 593  GLU   C OE2   1 
ATOM   3394 N N     . LYS   A 1 594  ? 159.110 69.568  85.196  1.00 85.91  ? 594  LYS   C N     1 
ATOM   3395 C CA    . LYS   A 1 594  ? 159.842 68.764  84.222  1.00 81.08  ? 594  LYS   C CA    1 
ATOM   3396 C C     . LYS   A 1 594  ? 159.297 68.918  82.805  1.00 80.97  ? 594  LYS   C C     1 
ATOM   3397 O O     . LYS   A 1 594  ? 159.780 68.267  81.878  1.00 77.92  ? 594  LYS   C O     1 
ATOM   3398 C CB    . LYS   A 1 594  ? 159.833 67.286  84.608  1.00 86.14  ? 594  LYS   C CB    1 
ATOM   3399 C CG    . LYS   A 1 594  ? 158.480 66.591  84.466  1.00 87.24  ? 594  LYS   C CG    1 
ATOM   3400 C CD    . LYS   A 1 594  ? 158.588 65.098  84.776  1.00 89.36  ? 594  LYS   C CD    1 
ATOM   3401 C CE    . LYS   A 1 594  ? 159.231 64.334  83.621  1.00 93.46  ? 594  LYS   C CE    1 
ATOM   3402 N NZ    . LYS   A 1 594  ? 159.192 62.866  83.840  1.00 96.97  ? 594  LYS   C NZ    1 
ATOM   3403 N N     . LYS   A 1 595  ? 158.276 69.755  82.633  1.00 80.88  ? 595  LYS   C N     1 
ATOM   3404 C CA    . LYS   A 1 595  ? 157.665 69.951  81.323  1.00 80.20  ? 595  LYS   C CA    1 
ATOM   3405 C C     . LYS   A 1 595  ? 158.286 71.145  80.609  1.00 74.50  ? 595  LYS   C C     1 
ATOM   3406 O O     . LYS   A 1 595  ? 157.854 71.529  79.517  1.00 67.65  ? 595  LYS   C O     1 
ATOM   3407 C CB    . LYS   A 1 595  ? 156.155 70.136  81.462  1.00 77.30  ? 595  LYS   C CB    1 
ATOM   3408 C CG    . LYS   A 1 595  ? 155.436 68.908  81.997  1.00 80.21  ? 595  LYS   C CG    1 
ATOM   3409 C CD    . LYS   A 1 595  ? 153.937 69.136  82.095  1.00 85.50  ? 595  LYS   C CD    1 
ATOM   3410 C CE    . LYS   A 1 595  ? 153.227 67.913  82.651  1.00 84.07  ? 595  LYS   C CE    1 
ATOM   3411 N NZ    . LYS   A 1 595  ? 153.283 66.764  81.706  1.00 84.00  ? 595  LYS   C NZ    1 
ATOM   3412 N N     . LEU   A 1 596  ? 159.293 71.732  81.245  1.00 71.53  ? 596  LEU   C N     1 
ATOM   3413 C CA    . LEU   A 1 596  ? 159.983 72.890  80.703  1.00 65.62  ? 596  LEU   C CA    1 
ATOM   3414 C C     . LEU   A 1 596  ? 161.219 72.434  79.934  1.00 66.83  ? 596  LEU   C C     1 
ATOM   3415 O O     . LEU   A 1 596  ? 161.857 71.445  80.298  1.00 70.30  ? 596  LEU   C O     1 
ATOM   3416 C CB    . LEU   A 1 596  ? 160.378 73.840  81.843  1.00 65.59  ? 596  LEU   C CB    1 
ATOM   3417 C CG    . LEU   A 1 596  ? 159.227 74.284  82.790  1.00 62.74  ? 596  LEU   C CG    1 
ATOM   3418 C CD1   . LEU   A 1 596  ? 159.782 75.254  83.832  1.00 58.20  ? 596  LEU   C CD1   1 
ATOM   3419 C CD2   . LEU   A 1 596  ? 158.106 74.918  81.986  1.00 55.81  ? 596  LEU   C CD2   1 
ATOM   3420 N N     . SER   A 1 597  ? 161.552 73.150  78.868  1.00 64.85  ? 597  SER   C N     1 
ATOM   3421 C CA    . SER   A 1 597  ? 162.701 72.787  78.040  1.00 69.15  ? 597  SER   C CA    1 
ATOM   3422 C C     . SER   A 1 597  ? 164.035 73.164  78.661  1.00 69.50  ? 597  SER   C C     1 
ATOM   3423 O O     . SER   A 1 597  ? 164.202 74.270  79.182  1.00 70.08  ? 597  SER   C O     1 
ATOM   3424 C CB    . SER   A 1 597  ? 162.585 73.419  76.675  1.00 67.20  ? 597  SER   C CB    1 
ATOM   3425 O OG    . SER   A 1 597  ? 163.782 73.282  75.954  1.00 67.67  ? 597  SER   C OG    1 
ATOM   3426 N N     . CYS   A 1 598  ? 164.991 72.238  78.587  1.00 68.79  ? 598  CYS   C N     1 
ATOM   3427 C CA    . CYS   A 1 598  ? 166.333 72.470  79.107  1.00 73.34  ? 598  CYS   C CA    1 
ATOM   3428 C C     . CYS   A 1 598  ? 167.087 73.494  78.276  1.00 73.90  ? 598  CYS   C C     1 
ATOM   3429 O O     . CYS   A 1 598  ? 167.726 74.393  78.824  1.00 73.17  ? 598  CYS   C O     1 
ATOM   3430 C CB    . CYS   A 1 598  ? 167.140 71.177  79.143  1.00 90.68  ? 598  CYS   C CB    1 
ATOM   3431 S SG    . CYS   A 1 598  ? 168.793 71.384  79.847  1.00 73.46  ? 598  CYS   C SG    1 
ATOM   3432 N N     . LYS   A 1 599  ? 167.040 73.347  76.956  1.00 70.94  ? 599  LYS   C N     1 
ATOM   3433 C CA    . LYS   A 1 599  ? 167.758 74.262  76.080  1.00 74.51  ? 599  LYS   C CA    1 
ATOM   3434 C C     . LYS   A 1 599  ? 167.230 75.677  76.243  1.00 68.98  ? 599  LYS   C C     1 
ATOM   3435 O O     . LYS   A 1 599  ? 167.998 76.640  76.246  1.00 71.43  ? 599  LYS   C O     1 
ATOM   3436 C CB    . LYS   A 1 599  ? 167.659 73.810  74.624  1.00 75.10  ? 599  LYS   C CB    1 
ATOM   3437 C CG    . LYS   A 1 599  ? 168.468 72.557  74.310  1.00 78.90  ? 599  LYS   C CG    1 
ATOM   3438 C CD    . LYS   A 1 599  ? 168.330 72.150  72.849  1.00 91.31  ? 599  LYS   C CD    1 
ATOM   3439 C CE    . LYS   A 1 599  ? 169.172 70.916  72.537  1.00 95.11  ? 599  LYS   C CE    1 
ATOM   3440 N NZ    . LYS   A 1 599  ? 169.037 70.498  71.116  1.00 88.78  ? 599  LYS   C NZ    1 
ATOM   3441 N N     . ILE   A 1 600  ? 165.918 75.801  76.412  1.00 61.61  ? 600  ILE   C N     1 
ATOM   3442 C CA    . ILE   A 1 600  ? 165.316 77.111  76.602  1.00 66.23  ? 600  ILE   C CA    1 
ATOM   3443 C C     . ILE   A 1 600  ? 165.720 77.681  77.950  1.00 68.30  ? 600  ILE   C C     1 
ATOM   3444 O O     . ILE   A 1 600  ? 166.029 78.870  78.049  1.00 56.38  ? 600  ILE   C O     1 
ATOM   3445 C CB    . ILE   A 1 600  ? 163.786 77.054  76.487  1.00 64.15  ? 600  ILE   C CB    1 
ATOM   3446 C CG1   . ILE   A 1 600  ? 163.370 76.577  75.065  1.00 65.26  ? 600  ILE   C CG1   1 
ATOM   3447 C CG2   . ILE   A 1 600  ? 163.187 78.422  76.800  1.00 61.34  ? 600  ILE   C CG2   1 
ATOM   3448 C CD1   . ILE   A 1 600  ? 163.846 77.451  73.912  1.00 74.33  ? 600  ILE   C CD1   1 
ATOM   3449 N N     . SER   A 1 601  ? 165.726 76.837  78.983  1.00 63.01  ? 601  SER   C N     1 
ATOM   3450 C CA    . SER   A 1 601  ? 166.129 77.263  80.315  1.00 57.91  ? 601  SER   C CA    1 
ATOM   3451 C C     . SER   A 1 601  ? 167.561 77.790  80.295  1.00 61.16  ? 601  SER   C C     1 
ATOM   3452 O O     . SER   A 1 601  ? 167.878 78.780  80.957  1.00 59.22  ? 601  SER   C O     1 
ATOM   3453 C CB    . SER   A 1 601  ? 166.015 76.113  81.293  1.00 58.50  ? 601  SER   C CB    1 
ATOM   3454 O OG    . SER   A 1 601  ? 164.677 75.730  81.469  1.00 60.59  ? 601  SER   C OG    1 
ATOM   3455 N N     . GLN   A 1 602  ? 168.425 77.149  79.515  1.00 63.37  ? 602  GLN   C N     1 
ATOM   3456 C CA    . GLN   A 1 602  ? 169.806 77.598  79.409  1.00 63.94  ? 602  GLN   C CA    1 
ATOM   3457 C C     . GLN   A 1 602  ? 169.909 78.952  78.712  1.00 55.93  ? 602  GLN   C C     1 
ATOM   3458 O O     . GLN   A 1 602  ? 170.664 79.824  79.154  1.00 58.74  ? 602  GLN   C O     1 
ATOM   3459 C CB    . GLN   A 1 602  ? 170.637 76.560  78.658  1.00 73.02  ? 602  GLN   C CB    1 
ATOM   3460 C CG    . GLN   A 1 602  ? 170.853 75.269  79.427  1.00 77.74  ? 602  GLN   C CG    1 
ATOM   3461 C CD    . GLN   A 1 602  ? 171.480 74.191  78.572  1.00 89.89  ? 602  GLN   C CD    1 
ATOM   3462 O OE1   . GLN   A 1 602  ? 171.521 74.307  77.344  1.00 88.33  ? 602  GLN   C OE1   1 
ATOM   3463 N NE2   . GLN   A 1 602  ? 171.968 73.135  79.211  1.00 88.54  ? 602  GLN   C NE2   1 
ATOM   3464 N N     . GLN   A 1 603  ? 169.136 79.142  77.645  1.00 57.18  ? 603  GLN   C N     1 
ATOM   3465 C CA    . GLN   A 1 603  ? 169.165 80.395  76.901  1.00 56.44  ? 603  GLN   C CA    1 
ATOM   3466 C C     . GLN   A 1 603  ? 168.647 81.564  77.731  1.00 54.70  ? 603  GLN   C C     1 
ATOM   3467 O O     . GLN   A 1 603  ? 169.209 82.660  77.691  1.00 53.59  ? 603  GLN   C O     1 
ATOM   3468 C CB    . GLN   A 1 603  ? 168.339 80.266  75.623  1.00 60.63  ? 603  GLN   C CB    1 
ATOM   3469 C CG    . GLN   A 1 603  ? 168.951 79.353  74.577  1.00 64.51  ? 603  GLN   C CG    1 
ATOM   3470 C CD    . GLN   A 1 603  ? 168.029 79.132  73.407  1.00 69.92  ? 603  GLN   C CD    1 
ATOM   3471 O OE1   . GLN   A 1 603  ? 166.872 79.559  73.434  1.00 67.73  ? 603  GLN   C OE1   1 
ATOM   3472 N NE2   . GLN   A 1 603  ? 168.527 78.463  72.377  1.00 65.49  ? 603  GLN   C NE2   1 
ATOM   3473 N N     . ILE   A 1 604  ? 167.586 81.326  78.496  1.00 52.38  ? 604  ILE   C N     1 
ATOM   3474 C CA    . ILE   A 1 604  ? 167.024 82.375  79.335  1.00 49.10  ? 604  ILE   C CA    1 
ATOM   3475 C C     . ILE   A 1 604  ? 167.919 82.696  80.520  1.00 49.57  ? 604  ILE   C C     1 
ATOM   3476 O O     . ILE   A 1 604  ? 168.048 83.861  80.896  1.00 47.58  ? 604  ILE   C O     1 
ATOM   3477 C CB    . ILE   A 1 604  ? 165.604 82.023  79.810  1.00 47.99  ? 604  ILE   C CB    1 
ATOM   3478 C CG1   . ILE   A 1 604  ? 165.009 83.223  80.544  1.00 45.58  ? 604  ILE   C CG1   1 
ATOM   3479 C CG2   . ILE   A 1 604  ? 165.612 80.817  80.646  1.00 51.08  ? 604  ILE   C CG2   1 
ATOM   3480 C CD1   . ILE   A 1 604  ? 163.548 83.113  80.887  1.00 41.34  ? 604  ILE   C CD1   1 
ATOM   3481 N N     . ARG   A 1 605  ? 168.563 81.690  81.101  1.00 50.29  ? 605  ARG   C N     1 
ATOM   3482 C CA    . ARG   A 1 605  ? 169.446 81.947  82.226  1.00 47.11  ? 605  ARG   C CA    1 
ATOM   3483 C C     . ARG   A 1 605  ? 170.516 82.960  81.831  1.00 46.72  ? 605  ARG   C C     1 
ATOM   3484 O O     . ARG   A 1 605  ? 170.832 83.872  82.598  1.00 46.55  ? 605  ARG   C O     1 
ATOM   3485 C CB    . ARG   A 1 605  ? 170.091 80.661  82.716  1.00 48.27  ? 605  ARG   C CB    1 
ATOM   3486 C CG    . ARG   A 1 605  ? 170.898 80.800  83.998  1.00 46.80  ? 605  ARG   C CG    1 
ATOM   3487 C CD    . ARG   A 1 605  ? 171.431 79.493  84.480  1.00 47.48  ? 605  ARG   C CD    1 
ATOM   3488 N NE    . ARG   A 1 605  ? 170.361 78.554  84.844  1.00 53.26  ? 605  ARG   C NE    1 
ATOM   3489 C CZ    . ARG   A 1 605  ? 170.004 77.452  84.141  1.00 55.82  ? 605  ARG   C CZ    1 
ATOM   3490 N NH1   . ARG   A 1 605  ? 170.620 77.141  83.022  1.00 60.10  ? 605  ARG   C NH1   1 
ATOM   3491 N NH2   . ARG   A 1 605  ? 169.026 76.683  84.583  1.00 56.62  ? 605  ARG   C NH2   1 
ATOM   3492 N N     . LEU   A 1 606  ? 171.059 82.812  80.624  1.00 47.96  ? 606  LEU   C N     1 
ATOM   3493 C CA    . LEU   A 1 606  ? 172.071 83.741  80.139  1.00 46.63  ? 606  LEU   C CA    1 
ATOM   3494 C C     . LEU   A 1 606  ? 171.505 85.145  79.952  1.00 45.23  ? 606  LEU   C C     1 
ATOM   3495 O O     . LEU   A 1 606  ? 172.152 86.133  80.311  1.00 46.82  ? 606  LEU   C O     1 
ATOM   3496 C CB    . LEU   A 1 606  ? 172.635 83.245  78.802  1.00 48.27  ? 606  LEU   C CB    1 
ATOM   3497 C CG    . LEU   A 1 606  ? 173.472 81.958  78.848  1.00 51.41  ? 606  LEU   C CG    1 
ATOM   3498 C CD1   . LEU   A 1 606  ? 173.709 81.477  77.429  1.00 52.06  ? 606  LEU   C CD1   1 
ATOM   3499 C CD2   . LEU   A 1 606  ? 174.801 82.227  79.555  1.00 54.09  ? 606  LEU   C CD2   1 
ATOM   3500 N N     . GLU   A 1 607  ? 170.290 85.240  79.416  1.00 45.57  ? 607  GLU   C N     1 
ATOM   3501 C CA    . GLU   A 1 607  ? 169.678 86.546  79.192  1.00 45.20  ? 607  GLU   C CA    1 
ATOM   3502 C C     . GLU   A 1 607  ? 169.337 87.242  80.502  1.00 44.76  ? 607  GLU   C C     1 
ATOM   3503 O O     . GLU   A 1 607  ? 169.502 88.456  80.629  1.00 43.04  ? 607  GLU   C O     1 
ATOM   3504 C CB    . GLU   A 1 607  ? 168.414 86.415  78.343  1.00 47.63  ? 607  GLU   C CB    1 
ATOM   3505 C CG    . GLU   A 1 607  ? 168.663 85.989  76.905  1.00 51.42  ? 607  GLU   C CG    1 
ATOM   3506 C CD    . GLU   A 1 607  ? 169.532 86.952  76.142  1.00 52.75  ? 607  GLU   C CD    1 
ATOM   3507 O OE1   . GLU   A 1 607  ? 169.278 88.130  76.196  1.00 54.84  ? 607  GLU   C OE1   1 
ATOM   3508 O OE2   . GLU   A 1 607  ? 170.469 86.504  75.513  1.00 57.19  ? 607  GLU   C OE2   1 
ATOM   3509 N N     . LEU   A 1 608  ? 168.883 86.473  81.486  1.00 42.05  ? 608  LEU   C N     1 
ATOM   3510 C CA    . LEU   A 1 608  ? 168.537 87.044  82.778  1.00 37.74  ? 608  LEU   C CA    1 
ATOM   3511 C C     . LEU   A 1 608  ? 169.779 87.557  83.491  1.00 38.57  ? 608  LEU   C C     1 
ATOM   3512 O O     . LEU   A 1 608  ? 169.733 88.590  84.163  1.00 38.58  ? 608  LEU   C O     1 
ATOM   3513 C CB    . LEU   A 1 608  ? 167.816 86.013  83.648  1.00 36.48  ? 608  LEU   C CB    1 
ATOM   3514 C CG    . LEU   A 1 608  ? 166.395 85.599  83.191  1.00 35.69  ? 608  LEU   C CG    1 
ATOM   3515 C CD1   . LEU   A 1 608  ? 165.917 84.430  84.052  1.00 36.63  ? 608  LEU   C CD1   1 
ATOM   3516 C CD2   . LEU   A 1 608  ? 165.428 86.781  83.312  1.00 34.49  ? 608  LEU   C CD2   1 
ATOM   3517 N N     . LEU   A 1 609  ? 170.901 86.859  83.334  1.00 41.16  ? 609  LEU   C N     1 
ATOM   3518 C CA    . LEU   A 1 609  ? 172.135 87.311  83.960  1.00 39.11  ? 609  LEU   C CA    1 
ATOM   3519 C C     . LEU   A 1 609  ? 172.598 88.624  83.343  1.00 39.85  ? 609  LEU   C C     1 
ATOM   3520 O O     . LEU   A 1 609  ? 173.006 89.538  84.059  1.00 40.52  ? 609  LEU   C O     1 
ATOM   3521 C CB    . LEU   A 1 609  ? 173.234 86.254  83.822  1.00 41.41  ? 609  LEU   C CB    1 
ATOM   3522 C CG    . LEU   A 1 609  ? 174.597 86.582  84.485  1.00 39.21  ? 609  LEU   C CG    1 
ATOM   3523 C CD1   . LEU   A 1 609  ? 174.416 86.810  85.996  1.00 41.69  ? 609  LEU   C CD1   1 
ATOM   3524 C CD2   . LEU   A 1 609  ? 175.550 85.423  84.237  1.00 43.58  ? 609  LEU   C CD2   1 
ATOM   3525 N N     . LYS   A 1 610  ? 172.519 88.726  82.013  1.00 41.74  ? 610  LYS   C N     1 
ATOM   3526 C CA    . LYS   A 1 610  ? 172.886 89.964  81.330  1.00 41.62  ? 610  LYS   C CA    1 
ATOM   3527 C C     . LYS   A 1 610  ? 171.973 91.102  81.759  1.00 40.53  ? 610  LYS   C C     1 
ATOM   3528 O O     . LYS   A 1 610  ? 172.422 92.238  81.933  1.00 41.59  ? 610  LYS   C O     1 
ATOM   3529 C CB    . LYS   A 1 610  ? 172.826 89.786  79.815  1.00 43.53  ? 610  LYS   C CB    1 
ATOM   3530 C CG    . LYS   A 1 610  ? 173.946 88.925  79.241  1.00 48.91  ? 610  LYS   C CG    1 
ATOM   3531 C CD    . LYS   A 1 610  ? 173.954 88.949  77.716  1.00 52.57  ? 610  LYS   C CD    1 
ATOM   3532 C CE    . LYS   A 1 610  ? 172.804 88.132  77.143  1.00 53.24  ? 610  LYS   C CE    1 
ATOM   3533 N NZ    . LYS   A 1 610  ? 172.884 88.012  75.661  1.00 57.16  ? 610  LYS   C NZ    1 
ATOM   3534 N N     . TRP   A 1 611  ? 170.694 90.797  81.948  1.00 38.53  ? 611  TRP   C N     1 
ATOM   3535 C CA    . TRP   A 1 611  ? 169.720 91.778  82.396  1.00 35.36  ? 611  TRP   C CA    1 
ATOM   3536 C C     . TRP   A 1 611  ? 170.129 92.345  83.750  1.00 37.84  ? 611  TRP   C C     1 
ATOM   3537 O O     . TRP   A 1 611  ? 170.143 93.561  83.942  1.00 38.21  ? 611  TRP   C O     1 
ATOM   3538 C CB    . TRP   A 1 611  ? 168.334 91.143  82.458  1.00 34.24  ? 611  TRP   C CB    1 
ATOM   3539 C CG    . TRP   A 1 611  ? 167.228 92.049  82.885  1.00 30.57  ? 611  TRP   C CG    1 
ATOM   3540 C CD1   . TRP   A 1 611  ? 166.633 93.010  82.134  1.00 33.51  ? 611  TRP   C CD1   1 
ATOM   3541 C CD2   . TRP   A 1 611  ? 166.556 92.067  84.164  1.00 27.77  ? 611  TRP   C CD2   1 
ATOM   3542 N NE1   . TRP   A 1 611  ? 165.642 93.626  82.853  1.00 32.55  ? 611  TRP   C NE1   1 
ATOM   3543 C CE2   . TRP   A 1 611  ? 165.570 93.048  84.091  1.00 27.08  ? 611  TRP   C CE2   1 
ATOM   3544 C CE3   . TRP   A 1 611  ? 166.684 91.313  85.331  1.00 29.19  ? 611  TRP   C CE3   1 
ATOM   3545 C CZ2   . TRP   A 1 611  ? 164.737 93.328  85.157  1.00 26.62  ? 611  TRP   C CZ2   1 
ATOM   3546 C CZ3   . TRP   A 1 611  ? 165.846 91.590  86.399  1.00 26.53  ? 611  TRP   C CZ3   1 
ATOM   3547 C CH2   . TRP   A 1 611  ? 164.891 92.564  86.310  1.00 24.29  ? 611  TRP   C CH2   1 
ATOM   3548 N N     . ILE   A 1 612  ? 170.510 91.462  84.676  1.00 38.30  ? 612  ILE   C N     1 
ATOM   3549 C CA    . ILE   A 1 612  ? 170.973 91.921  85.980  1.00 34.96  ? 612  ILE   C CA    1 
ATOM   3550 C C     . ILE   A 1 612  ? 172.232 92.754  85.838  1.00 37.77  ? 612  ILE   C C     1 
ATOM   3551 O O     . ILE   A 1 612  ? 172.348 93.807  86.464  1.00 39.08  ? 612  ILE   C O     1 
ATOM   3552 C CB    . ILE   A 1 612  ? 171.264 90.750  86.938  1.00 30.91  ? 612  ILE   C CB    1 
ATOM   3553 C CG1   . ILE   A 1 612  ? 169.964 90.048  87.313  1.00 29.37  ? 612  ILE   C CG1   1 
ATOM   3554 C CG2   . ILE   A 1 612  ? 171.982 91.276  88.194  1.00 31.89  ? 612  ILE   C CG2   1 
ATOM   3555 C CD1   . ILE   A 1 612  ? 170.172 88.737  88.017  1.00 31.85  ? 612  ILE   C CD1   1 
ATOM   3556 N N     . GLU   A 1 613  ? 173.185 92.300  85.032  1.00 39.45  ? 613  GLU   C N     1 
ATOM   3557 C CA    . GLU   A 1 613  ? 174.427 93.044  84.872  1.00 40.30  ? 613  GLU   C CA    1 
ATOM   3558 C C     . GLU   A 1 613  ? 174.173 94.485  84.458  1.00 42.22  ? 613  GLU   C C     1 
ATOM   3559 O O     . GLU   A 1 613  ? 174.749 95.414  85.029  1.00 43.05  ? 613  GLU   C O     1 
ATOM   3560 C CB    . GLU   A 1 613  ? 175.332 92.384  83.830  1.00 41.36  ? 613  GLU   C CB    1 
ATOM   3561 C CG    . GLU   A 1 613  ? 176.625 93.140  83.577  1.00 43.35  ? 613  GLU   C CG    1 
ATOM   3562 C CD    . GLU   A 1 613  ? 177.566 92.444  82.638  1.00 44.72  ? 613  GLU   C CD    1 
ATOM   3563 O OE1   . GLU   A 1 613  ? 177.231 91.400  82.144  1.00 44.25  ? 613  GLU   C OE1   1 
ATOM   3564 O OE2   . GLU   A 1 613  ? 178.635 92.969  82.417  1.00 47.42  ? 613  GLU   C OE2   1 
ATOM   3565 N N     . VAL   A 1 614  ? 173.305 94.676  83.472  1.00 40.47  ? 614  VAL   C N     1 
ATOM   3566 C CA    . VAL   A 1 614  ? 173.028 96.015  82.975  1.00 40.52  ? 614  VAL   C CA    1 
ATOM   3567 C C     . VAL   A 1 614  ? 172.319 96.871  84.013  1.00 42.36  ? 614  VAL   C C     1 
ATOM   3568 O O     . VAL   A 1 614  ? 172.669 98.038  84.198  1.00 43.62  ? 614  VAL   C O     1 
ATOM   3569 C CB    . VAL   A 1 614  ? 172.180 95.950  81.691  1.00 41.94  ? 614  VAL   C CB    1 
ATOM   3570 C CG1   . VAL   A 1 614  ? 171.745 97.357  81.269  1.00 40.81  ? 614  VAL   C CG1   1 
ATOM   3571 C CG2   . VAL   A 1 614  ? 172.993 95.291  80.584  1.00 42.55  ? 614  VAL   C CG2   1 
ATOM   3572 N N     . LYS   A 1 615  ? 171.310 96.309  84.672  1.00 39.22  ? 615  LYS   C N     1 
ATOM   3573 C CA    . LYS   A 1 615  ? 170.547 97.066  85.655  1.00 38.55  ? 615  LYS   C CA    1 
ATOM   3574 C C     . LYS   A 1 615  ? 171.362 97.340  86.918  1.00 42.12  ? 615  LYS   C C     1 
ATOM   3575 O O     . LYS   A 1 615  ? 171.212 98.389  87.541  1.00 44.32  ? 615  LYS   C O     1 
ATOM   3576 C CB    . LYS   A 1 615  ? 169.250 96.332  86.000  1.00 34.65  ? 615  LYS   C CB    1 
ATOM   3577 C CG    . LYS   A 1 615  ? 168.252 96.204  84.830  1.00 36.78  ? 615  LYS   C CG    1 
ATOM   3578 C CD    . LYS   A 1 615  ? 167.658 97.560  84.432  1.00 39.68  ? 615  LYS   C CD    1 
ATOM   3579 C CE    . LYS   A 1 615  ? 166.522 97.408  83.415  1.00 40.34  ? 615  LYS   C CE    1 
ATOM   3580 N NZ    . LYS   A 1 615  ? 167.027 97.123  82.042  1.00 43.27  ? 615  LYS   C NZ    1 
ATOM   3581 N N     . ALA   A 1 616  ? 172.218 96.395  87.301  1.00 40.82  ? 616  ALA   C N     1 
ATOM   3582 C CA    . ALA   A 1 616  ? 173.057 96.562  88.481  1.00 36.94  ? 616  ALA   C CA    1 
ATOM   3583 C C     . ALA   A 1 616  ? 174.088 97.665  88.256  1.00 41.83  ? 616  ALA   C C     1 
ATOM   3584 O O     . ALA   A 1 616  ? 174.341 98.476  89.148  1.00 41.86  ? 616  ALA   C O     1 
ATOM   3585 C CB    . ALA   A 1 616  ? 173.748 95.252  88.825  1.00 36.54  ? 616  ALA   C CB    1 
ATOM   3586 N N     . LYS   A 1 617  ? 174.663 97.714  87.052  1.00 45.15  ? 617  LYS   C N     1 
ATOM   3587 C CA    . LYS   A 1 617  ? 175.619 98.762  86.702  1.00 46.83  ? 617  LYS   C CA    1 
ATOM   3588 C C     . LYS   A 1 617  ? 174.933 100.113 86.552  1.00 48.51  ? 617  LYS   C C     1 
ATOM   3589 O O     . LYS   A 1 617  ? 175.461 101.145 86.974  1.00 50.70  ? 617  LYS   C O     1 
ATOM   3590 C CB    . LYS   A 1 617  ? 176.352 98.428  85.402  1.00 45.69  ? 617  LYS   C CB    1 
ATOM   3591 C CG    . LYS   A 1 617  ? 177.366 97.301  85.496  1.00 47.08  ? 617  LYS   C CG    1 
ATOM   3592 C CD    . LYS   A 1 617  ? 178.027 97.062  84.144  1.00 48.28  ? 617  LYS   C CD    1 
ATOM   3593 C CE    . LYS   A 1 617  ? 179.004 95.901  84.189  1.00 49.01  ? 617  LYS   C CE    1 
ATOM   3594 N NZ    . LYS   A 1 617  ? 179.647 95.669  82.865  1.00 47.60  ? 617  LYS   C NZ    1 
ATOM   3595 N N     . ALA   A 1 618  ? 173.745 100.110 85.955  1.00 48.73  ? 618  ALA   C N     1 
ATOM   3596 C CA    . ALA   A 1 618  ? 173.015 101.341 85.698  1.00 51.20  ? 618  ALA   C CA    1 
ATOM   3597 C C     . ALA   A 1 618  ? 172.304 101.808 86.953  1.00 55.20  ? 618  ALA   C C     1 
ATOM   3598 O O     . ALA   A 1 618  ? 171.071 101.835 87.016  1.00 56.94  ? 618  ALA   C O     1 
ATOM   3599 C CB    . ALA   A 1 618  ? 172.014 101.138 84.575  1.00 51.77  ? 618  ALA   C CB    1 
ATOM   3600 N N     . LYS   A 1 619  ? 173.085 102.201 87.949  1.00 54.73  ? 619  LYS   C N     1 
ATOM   3601 C CA    . LYS   A 1 619  ? 172.532 102.630 89.221  1.00 58.28  ? 619  LYS   C CA    1 
ATOM   3602 C C     . LYS   A 1 619  ? 172.035 104.062 89.112  1.00 61.72  ? 619  LYS   C C     1 
ATOM   3603 O O     . LYS   A 1 619  ? 172.663 105.001 89.602  1.00 59.71  ? 619  LYS   C O     1 
ATOM   3604 C CB    . LYS   A 1 619  ? 173.577 102.499 90.328  1.00 59.23  ? 619  LYS   C CB    1 
ATOM   3605 C CG    . LYS   A 1 619  ? 173.069 102.833 91.719  1.00 57.67  ? 619  LYS   C CG    1 
ATOM   3606 C CD    . LYS   A 1 619  ? 174.146 102.601 92.766  1.00 51.99  ? 619  LYS   C CD    1 
ATOM   3607 C CE    . LYS   A 1 619  ? 173.641 102.936 94.159  1.00 46.96  ? 619  LYS   C CE    1 
ATOM   3608 N NZ    . LYS   A 1 619  ? 173.372 104.394 94.312  1.00 47.82  ? 619  LYS   C NZ    1 
ATOM   3609 N N     . LYS   A 1 620  ? 170.902 104.206 88.442  1.00 63.06  ? 620  LYS   C N     1 
ATOM   3610 C CA    . LYS   A 1 620  ? 170.280 105.491 88.164  1.00 65.62  ? 620  LYS   C CA    1 
ATOM   3611 C C     . LYS   A 1 620  ? 168.901 105.547 88.804  1.00 64.86  ? 620  LYS   C C     1 
ATOM   3612 O O     . LYS   A 1 620  ? 168.335 104.511 89.154  1.00 66.35  ? 620  LYS   C O     1 
ATOM   3613 C CB    . LYS   A 1 620  ? 170.167 105.704 86.652  1.00 63.36  ? 620  LYS   C CB    1 
ATOM   3614 C CG    . LYS   A 1 620  ? 171.490 105.602 85.887  1.00 65.05  ? 620  LYS   C CG    1 
ATOM   3615 C CD    . LYS   A 1 620  ? 172.449 106.727 86.253  1.00 67.28  ? 620  LYS   C CD    1 
ATOM   3616 C CE    . LYS   A 1 620  ? 173.712 106.673 85.403  1.00 67.95  ? 620  LYS   C CE    1 
ATOM   3617 N NZ    . LYS   A 1 620  ? 174.681 107.743 85.775  1.00 71.38  ? 620  LYS   C NZ    1 
ATOM   3618 N N     . LEU   A 1 621  ? 168.346 106.746 88.945  1.00 67.05  ? 621  LEU   C N     1 
ATOM   3619 C CA    . LEU   A 1 621  ? 166.983 106.857 89.450  1.00 69.29  ? 621  LEU   C CA    1 
ATOM   3620 C C     . LEU   A 1 621  ? 166.001 106.531 88.334  1.00 65.63  ? 621  LEU   C C     1 
ATOM   3621 O O     . LEU   A 1 621  ? 165.990 107.184 87.291  1.00 65.53  ? 621  LEU   C O     1 
ATOM   3622 C CB    . LEU   A 1 621  ? 166.719 108.270 89.993  1.00 70.67  ? 621  LEU   C CB    1 
ATOM   3623 C CG    . LEU   A 1 621  ? 165.297 108.540 90.545  1.00 71.24  ? 621  LEU   C CG    1 
ATOM   3624 C CD1   . LEU   A 1 621  ? 165.044 107.679 91.781  1.00 67.36  ? 621  LEU   C CD1   1 
ATOM   3625 C CD2   . LEU   A 1 621  ? 165.170 110.019 90.885  1.00 74.75  ? 621  LEU   C CD2   1 
ATOM   3626 N N     . GLN   A 1 622  ? 165.205 105.491 88.551  1.00 63.34  ? 622  GLN   C N     1 
ATOM   3627 C CA    . GLN   A 1 622  ? 164.283 104.987 87.542  1.00 61.69  ? 622  GLN   C CA    1 
ATOM   3628 C C     . GLN   A 1 622  ? 163.287 104.015 88.163  1.00 57.01  ? 622  GLN   C C     1 
ATOM   3629 O O     . GLN   A 1 622  ? 163.382 103.700 89.347  1.00 55.93  ? 622  GLN   C O     1 
ATOM   3630 C CB    . GLN   A 1 622  ? 165.069 104.334 86.400  1.00 60.52  ? 622  GLN   C CB    1 
ATOM   3631 C CG    . GLN   A 1 622  ? 165.967 103.187 86.830  1.00 57.96  ? 622  GLN   C CG    1 
ATOM   3632 C CD    . GLN   A 1 622  ? 166.878 102.718 85.706  1.00 56.93  ? 622  GLN   C CD    1 
ATOM   3633 O OE1   . GLN   A 1 622  ? 166.527 102.824 84.526  1.00 56.53  ? 622  GLN   C OE1   1 
ATOM   3634 N NE2   . GLN   A 1 622  ? 168.046 102.195 86.061  1.00 61.17  ? 622  GLN   C NE2   1 
ATOM   3635 N N     . ILE   A 1 623  ? 162.343 103.525 87.361  1.00 53.65  ? 623  ILE   C N     1 
ATOM   3636 C CA    . ILE   A 1 623  ? 161.337 102.589 87.866  1.00 55.96  ? 623  ILE   C CA    1 
ATOM   3637 C C     . ILE   A 1 623  ? 161.688 101.142 87.542  1.00 49.52  ? 623  ILE   C C     1 
ATOM   3638 O O     . ILE   A 1 623  ? 160.874 100.234 87.712  1.00 45.69  ? 623  ILE   C O     1 
ATOM   3639 C CB    . ILE   A 1 623  ? 159.941 102.934 87.322  1.00 58.81  ? 623  ILE   C CB    1 
ATOM   3640 C CG1   . ILE   A 1 623  ? 159.905 102.791 85.784  1.00 52.78  ? 623  ILE   C CG1   1 
ATOM   3641 C CG2   . ILE   A 1 623  ? 159.576 104.356 87.747  1.00 55.67  ? 623  ILE   C CG2   1 
ATOM   3642 C CD1   . ILE   A 1 623  ? 158.505 102.830 85.198  1.00 50.42  ? 623  ILE   C CD1   1 
ATOM   3643 N N     . GLN   A 1 624  ? 162.915 100.943 87.099  1.00 47.01  ? 624  GLN   C N     1 
ATOM   3644 C CA    . GLN   A 1 624  ? 163.474 99.624  86.860  1.00 40.10  ? 624  GLN   C CA    1 
ATOM   3645 C C     . GLN   A 1 624  ? 163.918 99.136  88.243  1.00 37.87  ? 624  GLN   C C     1 
ATOM   3646 O O     . GLN   A 1 624  ? 163.745 99.880  89.213  1.00 38.58  ? 624  GLN   C O     1 
ATOM   3647 C CB    . GLN   A 1 624  ? 164.636 99.741  85.863  1.00 45.38  ? 624  GLN   C CB    1 
ATOM   3648 C CG    . GLN   A 1 624  ? 164.334 100.562 84.621  1.00 49.52  ? 624  GLN   C CG    1 
ATOM   3649 C CD    . GLN   A 1 624  ? 163.288 99.948  83.721  1.00 46.54  ? 624  GLN   C CD    1 
ATOM   3650 O OE1   . GLN   A 1 624  ? 163.071 98.731  83.712  1.00 43.09  ? 624  GLN   C OE1   1 
ATOM   3651 N NE2   . GLN   A 1 624  ? 162.639 100.800 82.936  1.00 46.41  ? 624  GLN   C NE2   1 
ATOM   3652 N N     . PRO   A 1 625  ? 164.451 97.924  88.409  1.00 28.93  ? 625  PRO   C N     1 
ATOM   3653 C CA    . PRO   A 1 625  ? 164.882 97.360  89.663  1.00 22.57  ? 625  PRO   C CA    1 
ATOM   3654 C C     . PRO   A 1 625  ? 165.768 98.333  90.418  1.00 24.49  ? 625  PRO   C C     1 
ATOM   3655 O O     . PRO   A 1 625  ? 166.684 98.925  89.811  1.00 30.91  ? 625  PRO   C O     1 
ATOM   3656 C CB    . PRO   A 1 625  ? 165.607 96.099  89.224  1.00 22.26  ? 625  PRO   C CB    1 
ATOM   3657 C CG    . PRO   A 1 625  ? 164.950 95.732  87.923  1.00 23.88  ? 625  PRO   C CG    1 
ATOM   3658 C CD    . PRO   A 1 625  ? 164.682 97.046  87.261  1.00 28.41  ? 625  PRO   C CD    1 
ATOM   3659 N N     . SER   A 1 626  ? 165.545 98.517  91.707  1.00 20.19  ? 626  SER   C N     1 
ATOM   3660 C CA    . SER   A 1 626  ? 166.242 99.518  92.504  1.00 22.78  ? 626  SER   C CA    1 
ATOM   3661 C C     . SER   A 1 626  ? 167.146 98.938  93.591  1.00 25.72  ? 626  SER   C C     1 
ATOM   3662 O O     . SER   A 1 626  ? 167.080 99.359  94.747  1.00 28.71  ? 626  SER   C O     1 
ATOM   3663 C CB    . SER   A 1 626  ? 165.233 100.461 93.125  1.00 26.92  ? 626  SER   C CB    1 
ATOM   3664 O OG    . SER   A 1 626  ? 164.305 99.758  93.915  1.00 21.71  ? 626  SER   C OG    1 
ATOM   3665 N N     . GLN   A 1 627  ? 167.980 97.976  93.214  1.00 23.90  ? 627  GLN   C N     1 
ATOM   3666 C CA    . GLN   A 1 627  ? 168.969 97.330  94.089  1.00 20.25  ? 627  GLN   C CA    1 
ATOM   3667 C C     . GLN   A 1 627  ? 168.362 96.456  95.183  1.00 18.70  ? 627  GLN   C C     1 
ATOM   3668 O O     . GLN   A 1 627  ? 169.091 95.917  96.012  1.00 20.15  ? 627  GLN   C O     1 
ATOM   3669 C CB    . GLN   A 1 627  ? 169.874 98.374  94.757  1.00 22.69  ? 627  GLN   C CB    1 
ATOM   3670 C CG    . GLN   A 1 627  ? 170.671 99.245  93.798  1.00 31.96  ? 627  GLN   C CG    1 
ATOM   3671 C CD    . GLN   A 1 627  ? 171.763 98.479  93.082  1.00 34.10  ? 627  GLN   C CD    1 
ATOM   3672 O OE1   . GLN   A 1 627  ? 172.571 97.803  93.722  1.00 23.41  ? 627  GLN   C OE1   1 
ATOM   3673 N NE2   . GLN   A 1 627  ? 171.800 98.585  91.760  1.00 50.42  ? 627  GLN   C NE2   1 
ATOM   3674 N N     . LEU   A 1 628  ? 167.045 96.288  95.168  1.00 17.65  ? 628  LEU   C N     1 
ATOM   3675 C CA    . LEU   A 1 628  ? 166.381 95.383  96.098  1.00 16.17  ? 628  LEU   C CA    1 
ATOM   3676 C C     . LEU   A 1 628  ? 165.591 94.331  95.329  1.00 16.85  ? 628  LEU   C C     1 
ATOM   3677 O O     . LEU   A 1 628  ? 165.680 93.140  95.618  1.00 18.15  ? 628  LEU   C O     1 
ATOM   3678 C CB    . LEU   A 1 628  ? 165.471 96.155  97.063  1.00 13.27  ? 628  LEU   C CB    1 
ATOM   3679 C CG    . LEU   A 1 628  ? 164.700 95.305  98.109  1.00 9.81   ? 628  LEU   C CG    1 
ATOM   3680 C CD1   . LEU   A 1 628  ? 165.683 94.558  99.013  1.00 11.78  ? 628  LEU   C CD1   1 
ATOM   3681 C CD2   . LEU   A 1 628  ? 163.816 96.221  98.943  1.00 12.28  ? 628  LEU   C CD2   1 
ATOM   3682 N N     . GLU   A 1 629  ? 164.843 94.771  94.317  1.00 15.44  ? 629  GLU   C N     1 
ATOM   3683 C CA    . GLU   A 1 629  ? 164.051 93.851  93.510  1.00 12.48  ? 629  GLU   C CA    1 
ATOM   3684 C C     . GLU   A 1 629  ? 164.971 92.826  92.853  1.00 16.48  ? 629  GLU   C C     1 
ATOM   3685 O O     . GLU   A 1 629  ? 164.586 91.672  92.661  1.00 21.45  ? 629  GLU   C O     1 
ATOM   3686 C CB    . GLU   A 1 629  ? 163.240 94.613  92.462  1.00 13.23  ? 629  GLU   C CB    1 
ATOM   3687 C CG    . GLU   A 1 629  ? 162.042 93.849  91.899  1.00 12.44  ? 629  GLU   C CG    1 
ATOM   3688 C CD    . GLU   A 1 629  ? 162.350 92.989  90.722  1.00 16.31  ? 629  GLU   C CD    1 
ATOM   3689 O OE1   . GLU   A 1 629  ? 163.337 93.225  90.076  1.00 21.45  ? 629  GLU   C OE1   1 
ATOM   3690 O OE2   . GLU   A 1 629  ? 161.572 92.107  90.447  1.00 16.70  ? 629  GLU   C OE2   1 
ATOM   3691 N N     . LEU   A 1 630  ? 166.199 93.242  92.537  1.00 15.40  ? 630  LEU   C N     1 
ATOM   3692 C CA    . LEU   A 1 630  ? 167.185 92.335  91.973  1.00 14.84  ? 630  LEU   C CA    1 
ATOM   3693 C C     . LEU   A 1 630  ? 167.542 91.260  92.992  1.00 18.04  ? 630  LEU   C C     1 
ATOM   3694 O O     . LEU   A 1 630  ? 167.809 90.115  92.626  1.00 20.08  ? 630  LEU   C O     1 
ATOM   3695 C CB    . LEU   A 1 630  ? 168.452 93.099  91.556  1.00 15.95  ? 630  LEU   C CB    1 
ATOM   3696 C CG    . LEU   A 1 630  ? 168.287 94.086  90.384  1.00 18.75  ? 630  LEU   C CG    1 
ATOM   3697 C CD1   . LEU   A 1 630  ? 169.554 94.914  90.222  1.00 28.52  ? 630  LEU   C CD1   1 
ATOM   3698 C CD2   . LEU   A 1 630  ? 167.992 93.322  89.094  1.00 19.36  ? 630  LEU   C CD2   1 
ATOM   3699 N N     . PHE   A 1 631  ? 167.535 91.618  94.278  1.00 17.87  ? 631  PHE   C N     1 
ATOM   3700 C CA    . PHE   A 1 631  ? 167.833 90.646  95.321  1.00 16.68  ? 631  PHE   C CA    1 
ATOM   3701 C C     . PHE   A 1 631  ? 166.676 89.668  95.455  1.00 17.76  ? 631  PHE   C C     1 
ATOM   3702 O O     . PHE   A 1 631  ? 166.890 88.474  95.653  1.00 19.13  ? 631  PHE   C O     1 
ATOM   3703 C CB    . PHE   A 1 631  ? 168.107 91.324  96.665  1.00 16.32  ? 631  PHE   C CB    1 
ATOM   3704 C CG    . PHE   A 1 631  ? 169.390 92.130  96.740  1.00 16.42  ? 631  PHE   C CG    1 
ATOM   3705 C CD1   . PHE   A 1 631  ? 170.357 92.072  95.743  1.00 18.96  ? 631  PHE   C CD1   1 
ATOM   3706 C CD2   . PHE   A 1 631  ? 169.635 92.942  97.838  1.00 16.91  ? 631  PHE   C CD2   1 
ATOM   3707 C CE1   . PHE   A 1 631  ? 171.511 92.803  95.844  1.00 19.00  ? 631  PHE   C CE1   1 
ATOM   3708 C CE2   . PHE   A 1 631  ? 170.798 93.670  97.931  1.00 15.06  ? 631  PHE   C CE2   1 
ATOM   3709 C CZ    . PHE   A 1 631  ? 171.733 93.598  96.934  1.00 17.91  ? 631  PHE   C CZ    1 
ATOM   3710 N N     . TYR   A 1 632  ? 165.450 90.166  95.313  1.00 15.65  ? 632  TYR   C N     1 
ATOM   3711 C CA    . TYR   A 1 632  ? 164.283 89.290  95.343  1.00 12.90  ? 632  TYR   C CA    1 
ATOM   3712 C C     . TYR   A 1 632  ? 164.365 88.271  94.211  1.00 15.15  ? 632  TYR   C C     1 
ATOM   3713 O O     . TYR   A 1 632  ? 164.071 87.091  94.405  1.00 18.49  ? 632  TYR   C O     1 
ATOM   3714 C CB    . TYR   A 1 632  ? 162.985 90.098  95.251  1.00 10.89  ? 632  TYR   C CB    1 
ATOM   3715 C CG    . TYR   A 1 632  ? 162.457 90.588  96.588  1.00 10.24  ? 632  TYR   C CG    1 
ATOM   3716 C CD1   . TYR   A 1 632  ? 162.905 91.774  97.138  1.00 11.50  ? 632  TYR   C CD1   1 
ATOM   3717 C CD2   . TYR   A 1 632  ? 161.510 89.842  97.257  1.00 11.48  ? 632  TYR   C CD2   1 
ATOM   3718 C CE1   . TYR   A 1 632  ? 162.410 92.199  98.358  1.00 11.21  ? 632  TYR   C CE1   1 
ATOM   3719 C CE2   . TYR   A 1 632  ? 161.015 90.271  98.468  1.00 11.25  ? 632  TYR   C CE2   1 
ATOM   3720 C CZ    . TYR   A 1 632  ? 161.462 91.441  99.018  1.00 10.19  ? 632  TYR   C CZ    1 
ATOM   3721 O OH    . TYR   A 1 632  ? 160.963 91.854  100.234 1.00 14.19  ? 632  TYR   C OH    1 
ATOM   3722 N N     . CYS   A 1 633  ? 164.802 88.723  93.035  1.00 16.35  ? 633  CYS   C N     1 
ATOM   3723 C CA    . CYS   A 1 633  ? 164.981 87.834  91.891  1.00 16.26  ? 633  CYS   C CA    1 
ATOM   3724 C C     . CYS   A 1 633  ? 166.051 86.781  92.161  1.00 20.48  ? 633  CYS   C C     1 
ATOM   3725 O O     . CYS   A 1 633  ? 165.851 85.594  91.888  1.00 24.31  ? 633  CYS   C O     1 
ATOM   3726 C CB    . CYS   A 1 633  ? 165.388 88.627  90.654  1.00 16.26  ? 633  CYS   C CB    1 
ATOM   3727 S SG    . CYS   A 1 633  ? 164.087 89.656  89.970  1.00 19.22  ? 633  CYS   C SG    1 
ATOM   3728 N N     . LEU   A 1 634  ? 167.181 87.209  92.717  1.00 20.82  ? 634  LEU   C N     1 
ATOM   3729 C CA    . LEU   A 1 634  ? 168.267 86.291  93.031  1.00 21.57  ? 634  LEU   C CA    1 
ATOM   3730 C C     . LEU   A 1 634  ? 167.879 85.330  94.146  1.00 22.46  ? 634  LEU   C C     1 
ATOM   3731 O O     . LEU   A 1 634  ? 168.296 84.175  94.147  1.00 25.76  ? 634  LEU   C O     1 
ATOM   3732 C CB    . LEU   A 1 634  ? 169.527 87.072  93.410  1.00 21.32  ? 634  LEU   C CB    1 
ATOM   3733 C CG    . LEU   A 1 634  ? 170.213 87.844  92.263  1.00 17.34  ? 634  LEU   C CG    1 
ATOM   3734 C CD1   . LEU   A 1 634  ? 171.319 88.719  92.836  1.00 22.96  ? 634  LEU   C CD1   1 
ATOM   3735 C CD2   . LEU   A 1 634  ? 170.783 86.859  91.257  1.00 24.86  ? 634  LEU   C CD2   1 
ATOM   3736 N N     . TYR   A 1 635  ? 167.070 85.795  95.088  1.00 20.55  ? 635  TYR   C N     1 
ATOM   3737 C CA    . TYR   A 1 635  ? 166.588 84.934  96.157  1.00 19.73  ? 635  TYR   C CA    1 
ATOM   3738 C C     . TYR   A 1 635  ? 165.794 83.770  95.577  1.00 23.67  ? 635  TYR   C C     1 
ATOM   3739 O O     . TYR   A 1 635  ? 165.982 82.621  95.973  1.00 26.62  ? 635  TYR   C O     1 
ATOM   3740 C CB    . TYR   A 1 635  ? 165.743 85.715  97.158  1.00 19.00  ? 635  TYR   C CB    1 
ATOM   3741 C CG    . TYR   A 1 635  ? 165.260 84.878  98.309  1.00 18.53  ? 635  TYR   C CG    1 
ATOM   3742 C CD1   . TYR   A 1 635  ? 166.097 84.640  99.378  1.00 21.81  ? 635  TYR   C CD1   1 
ATOM   3743 C CD2   . TYR   A 1 635  ? 163.986 84.342  98.295  1.00 22.04  ? 635  TYR   C CD2   1 
ATOM   3744 C CE1   . TYR   A 1 635  ? 165.667 83.870  100.434 1.00 22.72  ? 635  TYR   C CE1   1 
ATOM   3745 C CE2   . TYR   A 1 635  ? 163.555 83.567  99.351  1.00 24.52  ? 635  TYR   C CE2   1 
ATOM   3746 C CZ    . TYR   A 1 635  ? 164.391 83.331  100.416 1.00 24.08  ? 635  TYR   C CZ    1 
ATOM   3747 O OH    . TYR   A 1 635  ? 163.963 82.557  101.466 1.00 27.75  ? 635  TYR   C OH    1 
ATOM   3748 N N     . GLU   A 1 636  ? 164.907 84.057  94.624  1.00 23.91  ? 636  GLU   C N     1 
ATOM   3749 C CA    . GLU   A 1 636  ? 164.136 82.989  93.992  1.00 23.42  ? 636  GLU   C CA    1 
ATOM   3750 C C     . GLU   A 1 636  ? 165.071 82.016  93.279  1.00 26.43  ? 636  GLU   C C     1 
ATOM   3751 O O     . GLU   A 1 636  ? 164.868 80.800  93.309  1.00 29.96  ? 636  GLU   C O     1 
ATOM   3752 C CB    . GLU   A 1 636  ? 163.130 83.567  92.995  1.00 18.30  ? 636  GLU   C CB    1 
ATOM   3753 C CG    . GLU   A 1 636  ? 161.999 84.350  93.631  1.00 17.23  ? 636  GLU   C CG    1 
ATOM   3754 C CD    . GLU   A 1 636  ? 161.058 83.500  94.422  1.00 23.58  ? 636  GLU   C CD    1 
ATOM   3755 O OE1   . GLU   A 1 636  ? 160.475 82.599  93.857  1.00 26.00  ? 636  GLU   C OE1   1 
ATOM   3756 O OE2   . GLU   A 1 636  ? 160.917 83.738  95.603  1.00 28.01  ? 636  GLU   C OE2   1 
ATOM   3757 N N     . MET   A 1 637  ? 166.125 82.550  92.672  1.00 25.04  ? 637  MET   C N     1 
ATOM   3758 C CA    . MET   A 1 637  ? 167.117 81.720  92.003  1.00 25.82  ? 637  MET   C CA    1 
ATOM   3759 C C     . MET   A 1 637  ? 168.097 81.131  93.011  1.00 28.35  ? 637  MET   C C     1 
ATOM   3760 O O     . MET   A 1 637  ? 169.242 81.574  93.123  1.00 30.46  ? 637  MET   C O     1 
ATOM   3761 C CB    . MET   A 1 637  ? 167.857 82.536  90.943  1.00 25.57  ? 637  MET   C CB    1 
ATOM   3762 C CG    . MET   A 1 637  ? 168.912 81.767  90.142  1.00 27.97  ? 637  MET   C CG    1 
ATOM   3763 S SD    . MET   A 1 637  ? 168.223 80.422  89.186  1.00 35.28  ? 637  MET   C SD    1 
ATOM   3764 C CE    . MET   A 1 637  ? 169.682 79.798  88.348  1.00 40.63  ? 637  MET   C CE    1 
ATOM   3765 N N     . GLN   A 1 638  ? 167.651 80.109  93.732  1.00 29.24  ? 638  GLN   C N     1 
ATOM   3766 C CA    . GLN   A 1 638  ? 168.460 79.497  94.784  1.00 28.85  ? 638  GLN   C CA    1 
ATOM   3767 C C     . GLN   A 1 638  ? 169.582 78.640  94.221  1.00 31.99  ? 638  GLN   C C     1 
ATOM   3768 O O     . GLN   A 1 638  ? 169.545 77.414  94.308  1.00 36.31  ? 638  GLN   C O     1 
ATOM   3769 C CB    . GLN   A 1 638  ? 167.594 78.628  95.705  1.00 30.36  ? 638  GLN   C CB    1 
ATOM   3770 C CG    . GLN   A 1 638  ? 166.631 79.383  96.590  1.00 27.18  ? 638  GLN   C CG    1 
ATOM   3771 C CD    . GLN   A 1 638  ? 167.323 79.963  97.814  1.00 28.93  ? 638  GLN   C CD    1 
ATOM   3772 O OE1   . GLN   A 1 638  ? 167.853 79.218  98.644  1.00 32.06  ? 638  GLN   C OE1   1 
ATOM   3773 N NE2   . GLN   A 1 638  ? 167.329 81.275  97.934  1.00 28.54  ? 638  GLN   C NE2   1 
ATOM   3774 N N     . GLU   A 1 639  ? 170.583 79.300  93.660  1.00 30.86  ? 639  GLU   C N     1 
ATOM   3775 C CA    . GLU   A 1 639  ? 171.757 78.633  93.118  1.00 35.59  ? 639  GLU   C CA    1 
ATOM   3776 C C     . GLU   A 1 639  ? 172.985 79.504  93.306  1.00 38.70  ? 639  GLU   C C     1 
ATOM   3777 O O     . GLU   A 1 639  ? 173.107 80.556  92.678  1.00 39.18  ? 639  GLU   C O     1 
ATOM   3778 C CB    . GLU   A 1 639  ? 171.562 78.324  91.634  1.00 36.82  ? 639  GLU   C CB    1 
ATOM   3779 C CG    . GLU   A 1 639  ? 172.731 77.601  90.995  1.00 44.09  ? 639  GLU   C CG    1 
ATOM   3780 C CD    . GLU   A 1 639  ? 172.517 77.277  89.546  1.00 49.55  ? 639  GLU   C CD    1 
ATOM   3781 O OE1   . GLU   A 1 639  ? 171.639 76.510  89.243  1.00 54.90  ? 639  GLU   C OE1   1 
ATOM   3782 O OE2   . GLU   A 1 639  ? 173.245 77.795  88.735  1.00 49.63  ? 639  GLU   C OE2   1 
ATOM   3783 N N     . GLU   A 1 640  ? 173.915 79.058  94.142  1.00 38.31  ? 640  GLU   C N     1 
ATOM   3784 C CA    . GLU   A 1 640  ? 175.095 79.853  94.459  1.00 38.12  ? 640  GLU   C CA    1 
ATOM   3785 C C     . GLU   A 1 640  ? 175.912 80.182  93.219  1.00 41.36  ? 640  GLU   C C     1 
ATOM   3786 O O     . GLU   A 1 640  ? 176.447 81.281  93.093  1.00 40.28  ? 640  GLU   C O     1 
ATOM   3787 C CB    . GLU   A 1 640  ? 175.965 79.120  95.477  1.00 40.10  ? 640  GLU   C CB    1 
ATOM   3788 C CG    . GLU   A 1 640  ? 175.328 78.989  96.854  1.00 45.08  ? 640  GLU   C CG    1 
ATOM   3789 C CD    . GLU   A 1 640  ? 174.333 77.860  96.936  1.00 58.21  ? 640  GLU   C CD    1 
ATOM   3790 O OE1   . GLU   A 1 640  ? 174.156 77.173  95.954  1.00 49.73  ? 640  GLU   C OE1   1 
ATOM   3791 O OE2   . GLU   A 1 640  ? 173.743 77.691  97.975  1.00 57.79  ? 640  GLU   C OE2   1 
ATOM   3792 N N     . ASP   A 1 641  ? 175.971 79.250  92.274  1.00 41.12  ? 641  ASP   C N     1 
ATOM   3793 C CA    . ASP   A 1 641  ? 176.742 79.467  91.055  1.00 43.20  ? 641  ASP   C CA    1 
ATOM   3794 C C     . ASP   A 1 641  ? 176.226 80.672  90.268  1.00 40.98  ? 641  ASP   C C     1 
ATOM   3795 O O     . ASP   A 1 641  ? 176.994 81.345  89.578  1.00 40.88  ? 641  ASP   C O     1 
ATOM   3796 C CB    . ASP   A 1 641  ? 176.705 78.224  90.164  1.00 48.36  ? 641  ASP   C CB    1 
ATOM   3797 C CG    . ASP   A 1 641  ? 177.506 77.058  90.728  1.00 54.85  ? 641  ASP   C CG    1 
ATOM   3798 O OD1   . ASP   A 1 641  ? 178.285 77.264  91.628  1.00 50.12  ? 641  ASP   C OD1   1 
ATOM   3799 O OD2   . ASP   A 1 641  ? 177.326 75.965  90.250  1.00 56.65  ? 641  ASP   C OD2   1 
ATOM   3800 N N     . PHE   A 1 642  ? 174.924 80.939  90.358  1.00 37.87  ? 642  PHE   C N     1 
ATOM   3801 C CA    . PHE   A 1 642  ? 174.332 82.066  89.655  1.00 34.49  ? 642  PHE   C CA    1 
ATOM   3802 C C     . PHE   A 1 642  ? 174.387 83.322  90.515  1.00 35.52  ? 642  PHE   C C     1 
ATOM   3803 O O     . PHE   A 1 642  ? 174.699 84.410  90.025  1.00 36.74  ? 642  PHE   C O     1 
ATOM   3804 C CB    . PHE   A 1 642  ? 172.879 81.774  89.286  1.00 37.42  ? 642  PHE   C CB    1 
ATOM   3805 C CG    . PHE   A 1 642  ? 172.244 82.830  88.419  1.00 36.16  ? 642  PHE   C CG    1 
ATOM   3806 C CD1   . PHE   A 1 642  ? 172.349 82.760  87.041  1.00 36.90  ? 642  PHE   C CD1   1 
ATOM   3807 C CD2   . PHE   A 1 642  ? 171.549 83.894  88.973  1.00 35.31  ? 642  PHE   C CD2   1 
ATOM   3808 C CE1   . PHE   A 1 642  ? 171.768 83.719  86.243  1.00 38.50  ? 642  PHE   C CE1   1 
ATOM   3809 C CE2   . PHE   A 1 642  ? 170.970 84.854  88.172  1.00 33.45  ? 642  PHE   C CE2   1 
ATOM   3810 C CZ    . PHE   A 1 642  ? 171.080 84.765  86.806  1.00 36.37  ? 642  PHE   C CZ    1 
ATOM   3811 N N     . VAL   A 1 643  ? 174.044 83.177  91.793  1.00 31.61  ? 643  VAL   C N     1 
ATOM   3812 C CA    . VAL   A 1 643  ? 173.939 84.322  92.686  1.00 29.25  ? 643  VAL   C CA    1 
ATOM   3813 C C     . VAL   A 1 643  ? 175.289 84.949  92.985  1.00 34.15  ? 643  VAL   C C     1 
ATOM   3814 O O     . VAL   A 1 643  ? 175.424 86.171  92.951  1.00 36.15  ? 643  VAL   C O     1 
ATOM   3815 C CB    . VAL   A 1 643  ? 173.254 83.919  94.004  1.00 27.16  ? 643  VAL   C CB    1 
ATOM   3816 C CG1   . VAL   A 1 643  ? 173.295 85.085  95.002  1.00 28.38  ? 643  VAL   C CG1   1 
ATOM   3817 C CG2   . VAL   A 1 643  ? 171.819 83.517  93.713  1.00 29.75  ? 643  VAL   C CG2   1 
ATOM   3818 N N     . GLN   A 1 644  ? 176.292 84.124  93.269  1.00 35.93  ? 644  GLN   C N     1 
ATOM   3819 C CA    . GLN   A 1 644  ? 177.614 84.634  93.607  1.00 34.71  ? 644  GLN   C CA    1 
ATOM   3820 C C     . GLN   A 1 644  ? 178.241 85.346  92.421  1.00 34.87  ? 644  GLN   C C     1 
ATOM   3821 O O     . GLN   A 1 644  ? 179.119 86.189  92.589  1.00 37.17  ? 644  GLN   C O     1 
ATOM   3822 C CB    . GLN   A 1 644  ? 178.530 83.503  94.075  1.00 34.08  ? 644  GLN   C CB    1 
ATOM   3823 C CG    . GLN   A 1 644  ? 178.144 82.905  95.416  1.00 38.06  ? 644  GLN   C CG    1 
ATOM   3824 C CD    . GLN   A 1 644  ? 179.050 81.758  95.816  1.00 40.70  ? 644  GLN   C CD    1 
ATOM   3825 O OE1   . GLN   A 1 644  ? 179.864 81.288  95.017  1.00 40.19  ? 644  GLN   C OE1   1 
ATOM   3826 N NE2   . GLN   A 1 644  ? 178.915 81.298  97.053  1.00 40.34  ? 644  GLN   C NE2   1 
ATOM   3827 N N     . ARG   A 1 645  ? 177.788 85.004  91.220  1.00 34.93  ? 645  ARG   C N     1 
ATOM   3828 C CA    . ARG   A 1 645  ? 178.294 85.629  90.009  1.00 34.85  ? 645  ARG   C CA    1 
ATOM   3829 C C     . ARG   A 1 645  ? 177.537 86.916  89.714  1.00 35.05  ? 645  ARG   C C     1 
ATOM   3830 O O     . ARG   A 1 645  ? 178.135 87.939  89.385  1.00 37.64  ? 645  ARG   C O     1 
ATOM   3831 C CB    . ARG   A 1 645  ? 178.166 84.678  88.832  1.00 36.00  ? 645  ARG   C CB    1 
ATOM   3832 C CG    . ARG   A 1 645  ? 178.720 85.198  87.528  1.00 39.47  ? 645  ARG   C CG    1 
ATOM   3833 C CD    . ARG   A 1 645  ? 178.662 84.167  86.471  1.00 44.95  ? 645  ARG   C CD    1 
ATOM   3834 N NE    . ARG   A 1 645  ? 179.132 84.676  85.198  1.00 54.47  ? 645  ARG   C NE    1 
ATOM   3835 C CZ    . ARG   A 1 645  ? 179.108 83.987  84.041  1.00 62.21  ? 645  ARG   C CZ    1 
ATOM   3836 N NH1   . ARG   A 1 645  ? 178.633 82.760  84.014  1.00 58.64  ? 645  ARG   C NH1   1 
ATOM   3837 N NH2   . ARG   A 1 645  ? 179.562 84.547  82.933  1.00 57.54  ? 645  ARG   C NH2   1 
ATOM   3838 N N     . ALA   A 1 646  ? 176.217 86.879  89.850  1.00 31.77  ? 646  ALA   C N     1 
ATOM   3839 C CA    . ALA   A 1 646  ? 175.400 88.057  89.590  1.00 29.38  ? 646  ALA   C CA    1 
ATOM   3840 C C     . ALA   A 1 646  ? 175.766 89.185  90.549  1.00 31.40  ? 646  ALA   C C     1 
ATOM   3841 O O     . ALA   A 1 646  ? 175.780 90.357  90.173  1.00 33.60  ? 646  ALA   C O     1 
ATOM   3842 C CB    . ALA   A 1 646  ? 173.931 87.712  89.727  1.00 30.71  ? 646  ALA   C CB    1 
ATOM   3843 N N     . MET   A 1 647  ? 176.098 88.822  91.785  1.00 32.06  ? 647  MET   C N     1 
ATOM   3844 C CA    . MET   A 1 647  ? 176.434 89.794  92.815  1.00 31.24  ? 647  MET   C CA    1 
ATOM   3845 C C     . MET   A 1 647  ? 177.745 90.536  92.561  1.00 34.30  ? 647  MET   C C     1 
ATOM   3846 O O     . MET   A 1 647  ? 178.039 91.521  93.241  1.00 34.09  ? 647  MET   C O     1 
ATOM   3847 C CB    . MET   A 1 647  ? 176.451 89.134  94.184  1.00 29.72  ? 647  MET   C CB    1 
ATOM   3848 C CG    . MET   A 1 647  ? 175.070 88.792  94.730  1.00 27.76  ? 647  MET   C CG    1 
ATOM   3849 S SD    . MET   A 1 647  ? 173.975 90.229  94.829  1.00 30.32  ? 647  MET   C SD    1 
ATOM   3850 C CE    . MET   A 1 647  ? 174.799 91.243  96.047  1.00 31.18  ? 647  MET   C CE    1 
ATOM   3851 N N     . ASP   A 1 648  ? 178.519 90.100  91.572  1.00 34.22  ? 648  ASP   C N     1 
ATOM   3852 C CA    . ASP   A 1 648  ? 179.775 90.763  91.239  1.00 33.07  ? 648  ASP   C CA    1 
ATOM   3853 C C     . ASP   A 1 648  ? 179.543 92.140  90.637  1.00 34.53  ? 648  ASP   C C     1 
ATOM   3854 O O     . ASP   A 1 648  ? 180.476 92.930  90.500  1.00 37.70  ? 648  ASP   C O     1 
ATOM   3855 C CB    . ASP   A 1 648  ? 180.607 89.929  90.265  1.00 35.03  ? 648  ASP   C CB    1 
ATOM   3856 C CG    . ASP   A 1 648  ? 181.310 88.758  90.918  1.00 39.89  ? 648  ASP   C CG    1 
ATOM   3857 O OD1   . ASP   A 1 648  ? 181.453 88.766  92.120  1.00 38.99  ? 648  ASP   C OD1   1 
ATOM   3858 O OD2   . ASP   A 1 648  ? 181.714 87.865  90.212  1.00 41.87  ? 648  ASP   C OD2   1 
ATOM   3859 N N     . TYR   A 1 649  ? 178.299 92.433  90.279  1.00 32.35  ? 649  TYR   C N     1 
ATOM   3860 C CA    . TYR   A 1 649  ? 177.967 93.702  89.653  1.00 30.23  ? 649  TYR   C CA    1 
ATOM   3861 C C     . TYR   A 1 649  ? 177.405 94.690  90.666  1.00 32.88  ? 649  TYR   C C     1 
ATOM   3862 O O     . TYR   A 1 649  ? 176.884 95.741  90.293  1.00 35.97  ? 649  TYR   C O     1 
ATOM   3863 C CB    . TYR   A 1 649  ? 176.961 93.477  88.527  1.00 34.22  ? 649  TYR   C CB    1 
ATOM   3864 C CG    . TYR   A 1 649  ? 177.437 92.469  87.512  1.00 37.40  ? 649  TYR   C CG    1 
ATOM   3865 C CD1   . TYR   A 1 649  ? 176.736 91.284  87.341  1.00 38.05  ? 649  TYR   C CD1   1 
ATOM   3866 C CD2   . TYR   A 1 649  ? 178.580 92.710  86.773  1.00 39.98  ? 649  TYR   C CD2   1 
ATOM   3867 C CE1   . TYR   A 1 649  ? 177.175 90.347  86.433  1.00 37.47  ? 649  TYR   C CE1   1 
ATOM   3868 C CE2   . TYR   A 1 649  ? 179.017 91.772  85.863  1.00 40.03  ? 649  TYR   C CE2   1 
ATOM   3869 C CZ    . TYR   A 1 649  ? 178.320 90.594  85.693  1.00 38.28  ? 649  TYR   C CZ    1 
ATOM   3870 O OH    . TYR   A 1 649  ? 178.762 89.660  84.784  1.00 40.26  ? 649  TYR   C OH    1 
ATOM   3871 N N     . PHE   A 1 650  ? 177.546 94.373  91.953  1.00 30.65  ? 650  PHE   C N     1 
ATOM   3872 C CA    . PHE   A 1 650  ? 177.044 95.238  93.015  1.00 27.53  ? 650  PHE   C CA    1 
ATOM   3873 C C     . PHE   A 1 650  ? 178.138 95.660  94.003  1.00 28.95  ? 650  PHE   C C     1 
ATOM   3874 O O     . PHE   A 1 650  ? 178.110 95.223  95.151  1.00 29.54  ? 650  PHE   C O     1 
ATOM   3875 C CB    . PHE   A 1 650  ? 175.963 94.504  93.818  1.00 27.36  ? 650  PHE   C CB    1 
ATOM   3876 C CG    . PHE   A 1 650  ? 174.739 94.094  93.053  1.00 30.02  ? 650  PHE   C CG    1 
ATOM   3877 C CD1   . PHE   A 1 650  ? 174.778 93.023  92.196  1.00 31.95  ? 650  PHE   C CD1   1 
ATOM   3878 C CD2   . PHE   A 1 650  ? 173.540 94.753  93.227  1.00 27.57  ? 650  PHE   C CD2   1 
ATOM   3879 C CE1   . PHE   A 1 650  ? 173.661 92.612  91.520  1.00 27.92  ? 650  PHE   C CE1   1 
ATOM   3880 C CE2   . PHE   A 1 650  ? 172.413 94.347  92.552  1.00 25.41  ? 650  PHE   C CE2   1 
ATOM   3881 C CZ    . PHE   A 1 650  ? 172.480 93.268  91.697  1.00 23.70  ? 650  PHE   C CZ    1 
ATOM   3882 N N     . PRO   A 1 651  ? 179.107 96.499  93.591  1.00 28.85  ? 651  PRO   C N     1 
ATOM   3883 C CA    . PRO   A 1 651  ? 180.212 96.988  94.404  1.00 25.37  ? 651  PRO   C CA    1 
ATOM   3884 C C     . PRO   A 1 651  ? 179.732 97.910  95.519  1.00 23.08  ? 651  PRO   C C     1 
ATOM   3885 O O     . PRO   A 1 651  ? 180.397 98.064  96.548  1.00 24.67  ? 651  PRO   C O     1 
ATOM   3886 C CB    . PRO   A 1 651  ? 181.071 97.740  93.379  1.00 25.38  ? 651  PRO   C CB    1 
ATOM   3887 C CG    . PRO   A 1 651  ? 180.112 98.118  92.270  1.00 30.83  ? 651  PRO   C CG    1 
ATOM   3888 C CD    . PRO   A 1 651  ? 179.115 96.982  92.207  1.00 31.47  ? 651  PRO   C CD    1 
ATOM   3889 N N     . LYS   A 1 652  ? 178.562 98.503  95.319  1.00 21.69  ? 652  LYS   C N     1 
ATOM   3890 C CA    . LYS   A 1 652  ? 177.971 99.379  96.313  1.00 18.86  ? 652  LYS   C CA    1 
ATOM   3891 C C     . LYS   A 1 652  ? 176.511 99.021  96.488  1.00 20.88  ? 652  LYS   C C     1 
ATOM   3892 O O     . LYS   A 1 652  ? 175.748 99.021  95.520  1.00 28.41  ? 652  LYS   C O     1 
ATOM   3893 C CB    . LYS   A 1 652  ? 178.110 100.840 95.895  1.00 24.22  ? 652  LYS   C CB    1 
ATOM   3894 C CG    . LYS   A 1 652  ? 179.548 101.311 95.739  1.00 29.33  ? 652  LYS   C CG    1 
ATOM   3895 C CD    . LYS   A 1 652  ? 179.611 102.791 95.427  1.00 30.25  ? 652  LYS   C CD    1 
ATOM   3896 C CE    . LYS   A 1 652  ? 181.045 103.262 95.278  1.00 34.22  ? 652  LYS   C CE    1 
ATOM   3897 N NZ    . LYS   A 1 652  ? 181.118 104.713 94.978  1.00 44.67  ? 652  LYS   C NZ    1 
ATOM   3898 N N     . ILE   A 1 653  ? 176.119 98.705  97.711  1.00 18.21  ? 653  ILE   C N     1 
ATOM   3899 C CA    . ILE   A 1 653  ? 174.748 98.308  97.973  1.00 14.99  ? 653  ILE   C CA    1 
ATOM   3900 C C     . ILE   A 1 653  ? 174.025 99.332  98.835  1.00 15.88  ? 653  ILE   C C     1 
ATOM   3901 O O     . ILE   A 1 653  ? 174.393 99.567  99.983  1.00 19.49  ? 653  ILE   C O     1 
ATOM   3902 C CB    . ILE   A 1 653  ? 174.710 96.916  98.638  1.00 14.33  ? 653  ILE   C CB    1 
ATOM   3903 C CG1   . ILE   A 1 653  ? 175.335 95.874  97.680  1.00 17.13  ? 653  ILE   C CG1   1 
ATOM   3904 C CG2   . ILE   A 1 653  ? 173.283 96.541  99.015  1.00 18.98  ? 653  ILE   C CG2   1 
ATOM   3905 C CD1   . ILE   A 1 653  ? 175.538 94.499  98.288  1.00 18.38  ? 653  ILE   C CD1   1 
ATOM   3906 N N     . GLU   A 1 654  ? 172.985 99.930  98.272  1.00 16.70  ? 654  GLU   C N     1 
ATOM   3907 C CA    . GLU   A 1 654  ? 172.176 100.910 98.987  1.00 16.69  ? 654  GLU   C CA    1 
ATOM   3908 C C     . GLU   A 1 654  ? 170.738 100.423 99.043  1.00 19.04  ? 654  GLU   C C     1 
ATOM   3909 O O     . GLU   A 1 654  ? 170.053 100.387 98.023  1.00 24.76  ? 654  GLU   C O     1 
ATOM   3910 C CB    . GLU   A 1 654  ? 172.261 102.276 98.302  1.00 23.88  ? 654  GLU   C CB    1 
ATOM   3911 C CG    . GLU   A 1 654  ? 173.666 102.881 98.291  1.00 29.82  ? 654  GLU   C CG    1 
ATOM   3912 C CD    . GLU   A 1 654  ? 173.737 104.229 97.618  1.00 41.58  ? 654  GLU   C CD    1 
ATOM   3913 O OE1   . GLU   A 1 654  ? 172.757 104.641 97.041  1.00 41.56  ? 654  GLU   C OE1   1 
ATOM   3914 O OE2   . GLU   A 1 654  ? 174.777 104.843 97.671  1.00 40.81  ? 654  GLU   C OE2   1 
ATOM   3915 N N     . ILE   A 1 655  ? 170.302 99.987  100.220 1.00 16.26  ? 655  ILE   C N     1 
ATOM   3916 C CA    . ILE   A 1 655  ? 168.985 99.370  100.346 1.00 14.48  ? 655  ILE   C CA    1 
ATOM   3917 C C     . ILE   A 1 655  ? 168.162 99.922  101.507 1.00 17.92  ? 655  ILE   C C     1 
ATOM   3918 O O     . ILE   A 1 655  ? 168.709 100.393 102.503 1.00 19.29  ? 655  ILE   C O     1 
ATOM   3919 C CB    . ILE   A 1 655  ? 169.137 97.840  100.449 1.00 13.58  ? 655  ILE   C CB    1 
ATOM   3920 C CG1   . ILE   A 1 655  ? 170.062 97.477  101.633 1.00 14.70  ? 655  ILE   C CG1   1 
ATOM   3921 C CG2   . ILE   A 1 655  ? 169.659 97.285  99.134  1.00 17.88  ? 655  ILE   C CG2   1 
ATOM   3922 C CD1   . ILE   A 1 655  ? 170.247 95.983  101.860 1.00 16.77  ? 655  ILE   C CD1   1 
ATOM   3923 N N     . ASN   A 1 656  ? 166.839 99.834  101.364 1.00 18.46  ? 656  ASN   C N     1 
ATOM   3924 C CA    . ASN   A 1 656  ? 165.885 100.269 102.384 1.00 17.60  ? 656  ASN   C CA    1 
ATOM   3925 C C     . ASN   A 1 656  ? 165.008 99.099  102.810 1.00 19.37  ? 656  ASN   C C     1 
ATOM   3926 O O     . ASN   A 1 656  ? 164.316 98.500  101.989 1.00 24.05  ? 656  ASN   C O     1 
ATOM   3927 C CB    . ASN   A 1 656  ? 165.039 101.414 101.874 1.00 19.13  ? 656  ASN   C CB    1 
ATOM   3928 C CG    . ASN   A 1 656  ? 165.844 102.638 101.566 1.00 27.67  ? 656  ASN   C CG    1 
ATOM   3929 O OD1   . ASN   A 1 656  ? 166.337 103.322 102.468 1.00 26.55  ? 656  ASN   C OD1   1 
ATOM   3930 N ND2   . ASN   A 1 656  ? 165.991 102.933 100.301 1.00 36.04  ? 656  ASN   C ND2   1 
ATOM   3931 N N     . LEU   A 1 657  ? 165.088 98.741  104.085 1.00 17.88  ? 657  LEU   C N     1 
ATOM   3932 C CA    . LEU   A 1 657  ? 164.424 97.548  104.597 1.00 15.24  ? 657  LEU   C CA    1 
ATOM   3933 C C     . LEU   A 1 657  ? 163.291 97.897  105.559 1.00 19.76  ? 657  LEU   C C     1 
ATOM   3934 O O     . LEU   A 1 657  ? 163.523 98.540  106.585 1.00 23.59  ? 657  LEU   C O     1 
ATOM   3935 C CB    . LEU   A 1 657  ? 165.478 96.691  105.304 1.00 15.36  ? 657  LEU   C CB    1 
ATOM   3936 C CG    . LEU   A 1 657  ? 166.766 96.460  104.482 1.00 15.33  ? 657  LEU   C CG    1 
ATOM   3937 C CD1   . LEU   A 1 657  ? 167.794 95.747  105.326 1.00 16.28  ? 657  LEU   C CD1   1 
ATOM   3938 C CD2   . LEU   A 1 657  ? 166.440 95.649  103.252 1.00 19.80  ? 657  LEU   C CD2   1 
ATOM   3939 N N     . SER   A 1 658  ? 162.064 97.484  105.225 1.00 20.51  ? 658  SER   C N     1 
ATOM   3940 C CA    . SER   A 1 658  ? 160.913 97.813  106.065 1.00 21.34  ? 658  SER   C CA    1 
ATOM   3941 C C     . SER   A 1 658  ? 160.244 96.585  106.675 1.00 21.96  ? 658  SER   C C     1 
ATOM   3942 O O     . SER   A 1 658  ? 159.557 96.693  107.689 1.00 29.25  ? 658  SER   C O     1 
ATOM   3943 C CB    . SER   A 1 658  ? 159.881 98.583  105.269 1.00 23.50  ? 658  SER   C CB    1 
ATOM   3944 O OG    . SER   A 1 658  ? 159.371 97.805  104.226 1.00 27.22  ? 658  SER   C OG    1 
ATOM   3945 N N     . THR   A 1 659  ? 160.440 95.414  106.081 1.00 18.97  ? 659  THR   C N     1 
ATOM   3946 C CA    . THR   A 1 659  ? 159.811 94.217  106.639 1.00 17.44  ? 659  THR   C CA    1 
ATOM   3947 C C     . THR   A 1 659  ? 160.759 93.038  106.783 1.00 19.34  ? 659  THR   C C     1 
ATOM   3948 O O     . THR   A 1 659  ? 161.940 93.119  106.441 1.00 22.63  ? 659  THR   C O     1 
ATOM   3949 C CB    . THR   A 1 659  ? 158.586 93.775  105.832 1.00 19.15  ? 659  THR   C CB    1 
ATOM   3950 O OG1   . THR   A 1 659  ? 157.908 92.743  106.565 1.00 23.99  ? 659  THR   C OG1   1 
ATOM   3951 C CG2   . THR   A 1 659  ? 158.989 93.256  104.474 1.00 21.90  ? 659  THR   C CG2   1 
ATOM   3952 N N     . ARG   A 1 660  ? 160.234 91.939  107.316 1.00 18.62  ? 660  ARG   C N     1 
ATOM   3953 C CA    . ARG   A 1 660  ? 161.048 90.762  107.597 1.00 19.93  ? 660  ARG   C CA    1 
ATOM   3954 C C     . ARG   A 1 660  ? 161.533 90.076  106.324 1.00 21.56  ? 660  ARG   C C     1 
ATOM   3955 O O     . ARG   A 1 660  ? 162.645 89.548  106.283 1.00 23.44  ? 660  ARG   C O     1 
ATOM   3956 C CB    . ARG   A 1 660  ? 160.290 89.771  108.457 1.00 23.74  ? 660  ARG   C CB    1 
ATOM   3957 C CG    . ARG   A 1 660  ? 161.135 88.611  108.965 1.00 29.73  ? 660  ARG   C CG    1 
ATOM   3958 C CD    . ARG   A 1 660  ? 160.439 87.843  110.029 1.00 38.63  ? 660  ARG   C CD    1 
ATOM   3959 N NE    . ARG   A 1 660  ? 161.196 86.661  110.439 1.00 43.22  ? 660  ARG   C NE    1 
ATOM   3960 C CZ    . ARG   A 1 660  ? 162.228 86.668  111.316 1.00 49.80  ? 660  ARG   C CZ    1 
ATOM   3961 N NH1   . ARG   A 1 660  ? 162.626 87.799  111.863 1.00 46.75  ? 660  ARG   C NH1   1 
ATOM   3962 N NH2   . ARG   A 1 660  ? 162.844 85.540  111.632 1.00 49.04  ? 660  ARG   C NH2   1 
ATOM   3963 N N     . MET   A 1 661  ? 160.705 90.094  105.283 1.00 19.98  ? 661  MET   C N     1 
ATOM   3964 C CA    . MET   A 1 661  ? 161.099 89.497  104.013 1.00 19.37  ? 661  MET   C CA    1 
ATOM   3965 C C     . MET   A 1 661  ? 162.246 90.264  103.377 1.00 20.49  ? 661  MET   C C     1 
ATOM   3966 O O     . MET   A 1 661  ? 163.080 89.686  102.683 1.00 20.56  ? 661  MET   C O     1 
ATOM   3967 C CB    . MET   A 1 661  ? 159.927 89.435  103.049 1.00 15.25  ? 661  MET   C CB    1 
ATOM   3968 C CG    . MET   A 1 661  ? 158.891 88.423  103.419 1.00 17.87  ? 661  MET   C CG    1 
ATOM   3969 S SD    . MET   A 1 661  ? 157.525 88.400  102.280 1.00 19.18  ? 661  MET   C SD    1 
ATOM   3970 C CE    . MET   A 1 661  ? 158.211 87.551  100.862 1.00 13.38  ? 661  MET   C CE    1 
ATOM   3971 N N     . ASP   A 1 662  ? 162.298 91.568  103.619 1.00 19.35  ? 662  ASP   C N     1 
ATOM   3972 C CA    . ASP   A 1 662  ? 163.355 92.380  103.050 1.00 16.33  ? 662  ASP   C CA    1 
ATOM   3973 C C     . ASP   A 1 662  ? 164.682 91.957  103.648 1.00 18.71  ? 662  ASP   C C     1 
ATOM   3974 O O     . ASP   A 1 662  ? 165.698 91.899  102.954 1.00 19.37  ? 662  ASP   C O     1 
ATOM   3975 C CB    . ASP   A 1 662  ? 163.127 93.854  103.362 1.00 16.41  ? 662  ASP   C CB    1 
ATOM   3976 C CG    . ASP   A 1 662  ? 161.943 94.467  102.676 1.00 17.55  ? 662  ASP   C CG    1 
ATOM   3977 O OD1   . ASP   A 1 662  ? 161.520 93.985  101.651 1.00 15.13  ? 662  ASP   C OD1   1 
ATOM   3978 O OD2   . ASP   A 1 662  ? 161.433 95.429  103.216 1.00 22.18  ? 662  ASP   C OD2   1 
ATOM   3979 N N     . HIS   A 1 663  ? 164.661 91.638  104.938 1.00 19.09  ? 663  HIS   C N     1 
ATOM   3980 C CA    . HIS   A 1 663  ? 165.872 91.243  105.638 1.00 18.67  ? 663  HIS   C CA    1 
ATOM   3981 C C     . HIS   A 1 663  ? 166.363 89.863  105.217 1.00 20.41  ? 663  HIS   C C     1 
ATOM   3982 O O     . HIS   A 1 663  ? 167.565 89.667  105.036 1.00 22.86  ? 663  HIS   C O     1 
ATOM   3983 C CB    . HIS   A 1 663  ? 165.652 91.263  107.155 1.00 18.86  ? 663  HIS   C CB    1 
ATOM   3984 C CG    . HIS   A 1 663  ? 165.543 92.638  107.732 1.00 19.46  ? 663  HIS   C CG    1 
ATOM   3985 N ND1   . HIS   A 1 663  ? 166.595 93.517  107.743 1.00 23.34  ? 663  HIS   C ND1   1 
ATOM   3986 C CD2   . HIS   A 1 663  ? 164.510 93.281  108.321 1.00 20.84  ? 663  HIS   C CD2   1 
ATOM   3987 C CE1   . HIS   A 1 663  ? 166.211 94.649  108.302 1.00 24.31  ? 663  HIS   C CE1   1 
ATOM   3988 N NE2   . HIS   A 1 663  ? 164.953 94.530  108.665 1.00 20.14  ? 663  HIS   C NE2   1 
ATOM   3989 N N     . MET   A 1 664  ? 165.454 88.900  105.037 1.00 19.25  ? 664  MET   C N     1 
ATOM   3990 C CA    . MET   A 1 664  ? 165.910 87.560  104.666 1.00 17.35  ? 664  MET   C CA    1 
ATOM   3991 C C     . MET   A 1 664  ? 166.433 87.540  103.231 1.00 20.34  ? 664  MET   C C     1 
ATOM   3992 O O     . MET   A 1 664  ? 167.388 86.824  102.921 1.00 22.34  ? 664  MET   C O     1 
ATOM   3993 C CB    . MET   A 1 664  ? 164.795 86.523  104.841 1.00 19.10  ? 664  MET   C CB    1 
ATOM   3994 C CG    . MET   A 1 664  ? 163.796 86.447  103.695 1.00 23.00  ? 664  MET   C CG    1 
ATOM   3995 S SD    . MET   A 1 664  ? 162.459 85.265  103.988 1.00 24.94  ? 664  MET   C SD    1 
ATOM   3996 C CE    . MET   A 1 664  ? 161.557 85.405  102.442 1.00 21.48  ? 664  MET   C CE    1 
ATOM   3997 N N     . VAL   A 1 665  ? 165.834 88.358  102.368 1.00 20.40  ? 665  VAL   C N     1 
ATOM   3998 C CA    . VAL   A 1 665  ? 166.259 88.455  100.979 1.00 17.40  ? 665  VAL   C CA    1 
ATOM   3999 C C     . VAL   A 1 665  ? 167.593 89.183  100.841 1.00 20.57  ? 665  VAL   C C     1 
ATOM   4000 O O     . VAL   A 1 665  ? 168.490 88.718  100.131 1.00 22.20  ? 665  VAL   C O     1 
ATOM   4001 C CB    . VAL   A 1 665  ? 165.173 89.157  100.151 1.00 14.54  ? 665  VAL   C CB    1 
ATOM   4002 C CG1   . VAL   A 1 665  ? 165.684 89.480  98.774  1.00 18.96  ? 665  VAL   C CG1   1 
ATOM   4003 C CG2   . VAL   A 1 665  ? 163.963 88.239  100.047 1.00 17.51  ? 665  VAL   C CG2   1 
ATOM   4004 N N     . SER   A 1 666  ? 167.733 90.315  101.527 1.00 20.06  ? 666  SER   C N     1 
ATOM   4005 C CA    . SER   A 1 666  ? 168.972 91.075  101.483 1.00 17.38  ? 666  SER   C CA    1 
ATOM   4006 C C     . SER   A 1 666  ? 170.106 90.318  102.153 1.00 19.72  ? 666  SER   C C     1 
ATOM   4007 O O     . SER   A 1 666  ? 171.240 90.353  101.678 1.00 24.00  ? 666  SER   C O     1 
ATOM   4008 C CB    . SER   A 1 666  ? 168.775 92.422  102.143 1.00 16.44  ? 666  SER   C CB    1 
ATOM   4009 O OG    . SER   A 1 666  ? 167.897 93.210  101.391 1.00 18.58  ? 666  SER   C OG    1 
ATOM   4010 N N     . SER   A 1 667  ? 169.807 89.611  103.241 1.00 20.29  ? 667  SER   C N     1 
ATOM   4011 C CA    . SER   A 1 667  ? 170.828 88.843  103.938 1.00 19.87  ? 667  SER   C CA    1 
ATOM   4012 C C     . SER   A 1 667  ? 171.403 87.770  103.027 1.00 23.08  ? 667  SER   C C     1 
ATOM   4013 O O     . SER   A 1 667  ? 172.619 87.609  102.934 1.00 27.12  ? 667  SER   C O     1 
ATOM   4014 C CB    . SER   A 1 667  ? 170.249 88.206  105.182 1.00 20.50  ? 667  SER   C CB    1 
ATOM   4015 O OG    . SER   A 1 667  ? 171.212 87.443  105.849 1.00 27.27  ? 667  SER   C OG    1 
ATOM   4016 N N     . PHE   A 1 668  ? 170.526 87.053  102.325 1.00 23.89  ? 668  PHE   C N     1 
ATOM   4017 C CA    . PHE   A 1 668  ? 170.955 86.012  101.401 1.00 24.22  ? 668  PHE   C CA    1 
ATOM   4018 C C     . PHE   A 1 668  ? 171.892 86.552  100.326 1.00 26.28  ? 668  PHE   C C     1 
ATOM   4019 O O     . PHE   A 1 668  ? 172.957 85.983  100.076 1.00 28.36  ? 668  PHE   C O     1 
ATOM   4020 C CB    . PHE   A 1 668  ? 169.734 85.373  100.739 1.00 23.47  ? 668  PHE   C CB    1 
ATOM   4021 C CG    . PHE   A 1 668  ? 170.055 84.426  99.621  1.00 22.09  ? 668  PHE   C CG    1 
ATOM   4022 C CD1   . PHE   A 1 668  ? 170.458 83.130  99.876  1.00 22.45  ? 668  PHE   C CD1   1 
ATOM   4023 C CD2   . PHE   A 1 668  ? 169.947 84.838  98.304  1.00 25.70  ? 668  PHE   C CD2   1 
ATOM   4024 C CE1   . PHE   A 1 668  ? 170.745 82.268  98.836  1.00 24.12  ? 668  PHE   C CE1   1 
ATOM   4025 C CE2   . PHE   A 1 668  ? 170.233 83.984  97.270  1.00 25.57  ? 668  PHE   C CE2   1 
ATOM   4026 C CZ    . PHE   A 1 668  ? 170.634 82.696  97.533  1.00 25.19  ? 668  PHE   C CZ    1 
ATOM   4027 N N     . CYS   A 1 669  ? 171.486 87.635  99.673  1.00 23.82  ? 669  CYS   C N     1 
ATOM   4028 C CA    . CYS   A 1 669  ? 172.274 88.189  98.580  1.00 23.88  ? 669  CYS   C CA    1 
ATOM   4029 C C     . CYS   A 1 669  ? 173.582 88.814  99.045  1.00 27.09  ? 669  CYS   C C     1 
ATOM   4030 O O     . CYS   A 1 669  ? 174.608 88.668  98.383  1.00 30.19  ? 669  CYS   C O     1 
ATOM   4031 C CB    . CYS   A 1 669  ? 171.459 89.212  97.814  1.00 25.00  ? 669  CYS   C CB    1 
ATOM   4032 S SG    . CYS   A 1 669  ? 170.125 88.467  96.894  1.00 28.61  ? 669  CYS   C SG    1 
ATOM   4033 N N     . ILE   A 1 670  ? 173.557 89.511  100.176 1.00 24.71  ? 670  ILE   C N     1 
ATOM   4034 C CA    . ILE   A 1 670  ? 174.771 90.130  100.690 1.00 22.13  ? 670  ILE   C CA    1 
ATOM   4035 C C     . ILE   A 1 670  ? 175.769 89.074  101.135 1.00 24.59  ? 670  ILE   C C     1 
ATOM   4036 O O     . ILE   A 1 670  ? 176.966 89.208  100.890 1.00 26.83  ? 670  ILE   C O     1 
ATOM   4037 C CB    . ILE   A 1 670  ? 174.477 91.121  101.832 1.00 19.06  ? 670  ILE   C CB    1 
ATOM   4038 C CG1   . ILE   A 1 670  ? 173.731 92.345  101.263 1.00 19.50  ? 670  ILE   C CG1   1 
ATOM   4039 C CG2   . ILE   A 1 670  ? 175.781 91.549  102.513 1.00 22.23  ? 670  ILE   C CG2   1 
ATOM   4040 C CD1   . ILE   A 1 670  ? 173.138 93.262  102.312 1.00 19.76  ? 670  ILE   C CD1   1 
ATOM   4041 N N     . GLU   A 1 671  ? 175.291 88.027  101.806 1.00 26.22  ? 671  GLU   C N     1 
ATOM   4042 C CA    . GLU   A 1 671  ? 176.191 86.966  102.235 1.00 27.86  ? 671  GLU   C CA    1 
ATOM   4043 C C     . GLU   A 1 671  ? 176.892 86.335  101.037 1.00 30.13  ? 671  GLU   C C     1 
ATOM   4044 O O     . GLU   A 1 671  ? 178.104 86.115  101.064 1.00 31.43  ? 671  GLU   C O     1 
ATOM   4045 C CB    . GLU   A 1 671  ? 175.439 85.888  103.017 1.00 29.72  ? 671  GLU   C CB    1 
ATOM   4046 C CG    . GLU   A 1 671  ? 176.341 84.792  103.570 1.00 32.09  ? 671  GLU   C CG    1 
ATOM   4047 C CD    . GLU   A 1 671  ? 175.609 83.784  104.404 1.00 39.33  ? 671  GLU   C CD    1 
ATOM   4048 O OE1   . GLU   A 1 671  ? 174.418 83.906  104.548 1.00 35.79  ? 671  GLU   C OE1   1 
ATOM   4049 O OE2   . GLU   A 1 671  ? 176.245 82.887  104.902 1.00 47.31  ? 671  GLU   C OE2   1 
ATOM   4050 N N     . ASN   A 1 672  ? 176.142 86.079  99.965  1.00 29.12  ? 672  ASN   C N     1 
ATOM   4051 C CA    . ASN   A 1 672  ? 176.720 85.510  98.753  1.00 27.82  ? 672  ASN   C CA    1 
ATOM   4052 C C     . ASN   A 1 672  ? 177.286 86.594  97.849  1.00 30.64  ? 672  ASN   C C     1 
ATOM   4053 O O     . ASN   A 1 672  ? 176.853 86.755  96.708  1.00 33.10  ? 672  ASN   C O     1 
ATOM   4054 C CB    . ASN   A 1 672  ? 175.689 84.690  98.002  1.00 28.46  ? 672  ASN   C CB    1 
ATOM   4055 C CG    . ASN   A 1 672  ? 175.337 83.420  98.704  1.00 32.22  ? 672  ASN   C CG    1 
ATOM   4056 O OD1   . ASN   A 1 672  ? 176.213 82.725  99.234  1.00 36.01  ? 672  ASN   C OD1   1 
ATOM   4057 N ND2   . ASN   A 1 672  ? 174.074 83.099  98.724  1.00 30.05  ? 672  ASN   C ND2   1 
ATOM   4058 N N     . CYS   A 1 673  ? 178.259 87.333  98.369  1.00 31.06  ? 673  CYS   C N     1 
ATOM   4059 C CA    . CYS   A 1 673  ? 178.892 88.427  97.644  1.00 29.59  ? 673  CYS   C CA    1 
ATOM   4060 C C     . CYS   A 1 673  ? 180.300 88.666  98.161  1.00 33.04  ? 673  CYS   C C     1 
ATOM   4061 O O     . CYS   A 1 673  ? 180.507 88.877  99.355  1.00 34.19  ? 673  CYS   C O     1 
ATOM   4062 C CB    . CYS   A 1 673  ? 178.085 89.713  97.786  1.00 26.30  ? 673  CYS   C CB    1 
ATOM   4063 S SG    . CYS   A 1 673  ? 178.760 91.103  96.861  1.00 30.15  ? 673  CYS   C SG    1 
ATOM   4064 N N     . HIS   A 1 674  ? 181.271 88.631  97.261  1.00 33.74  ? 674  HIS   C N     1 
ATOM   4065 C CA    . HIS   A 1 674  ? 182.662 88.793  97.658  1.00 33.30  ? 674  HIS   C CA    1 
ATOM   4066 C C     . HIS   A 1 674  ? 183.275 90.086  97.131  1.00 33.77  ? 674  HIS   C C     1 
ATOM   4067 O O     . HIS   A 1 674  ? 184.481 90.298  97.255  1.00 33.86  ? 674  HIS   C O     1 
ATOM   4068 C CB    . HIS   A 1 674  ? 183.479 87.600  97.158  1.00 36.40  ? 674  HIS   C CB    1 
ATOM   4069 C CG    . HIS   A 1 674  ? 182.990 86.285  97.690  1.00 39.92  ? 674  HIS   C CG    1 
ATOM   4070 N ND1   . HIS   A 1 674  ? 183.166 85.899  99.001  1.00 45.68  ? 674  HIS   C ND1   1 
ATOM   4071 C CD2   . HIS   A 1 674  ? 182.326 85.271  97.084  1.00 39.64  ? 674  HIS   C CD2   1 
ATOM   4072 C CE1   . HIS   A 1 674  ? 182.630 84.704  99.179  1.00 44.89  ? 674  HIS   C CE1   1 
ATOM   4073 N NE2   . HIS   A 1 674  ? 182.116 84.302  98.033  1.00 41.90  ? 674  HIS   C NE2   1 
ATOM   4074 N N     . ARG   A 1 675  ? 182.461 90.938  96.518  1.00 31.42  ? 675  ARG   C N     1 
ATOM   4075 C CA    . ARG   A 1 675  ? 182.988 92.156  95.914  1.00 29.80  ? 675  ARG   C CA    1 
ATOM   4076 C C     . ARG   A 1 675  ? 182.210 93.419  96.267  1.00 28.91  ? 675  ARG   C C     1 
ATOM   4077 O O     . ARG   A 1 675  ? 182.114 94.332  95.450  1.00 29.21  ? 675  ARG   C O     1 
ATOM   4078 C CB    . ARG   A 1 675  ? 183.064 92.005  94.401  1.00 33.84  ? 675  ARG   C CB    1 
ATOM   4079 C CG    . ARG   A 1 675  ? 184.102 90.989  93.933  1.00 40.87  ? 675  ARG   C CG    1 
ATOM   4080 C CD    . ARG   A 1 675  ? 184.174 90.883  92.456  1.00 46.04  ? 675  ARG   C CD    1 
ATOM   4081 N NE    . ARG   A 1 675  ? 185.274 90.016  92.039  1.00 48.13  ? 675  ARG   C NE    1 
ATOM   4082 C CZ    . ARG   A 1 675  ? 185.236 88.661  91.990  1.00 53.62  ? 675  ARG   C CZ    1 
ATOM   4083 N NH1   . ARG   A 1 675  ? 184.144 87.998  92.314  1.00 47.80  ? 675  ARG   C NH1   1 
ATOM   4084 N NH2   . ARG   A 1 675  ? 186.313 87.994  91.609  1.00 52.55  ? 675  ARG   C NH2   1 
ATOM   4085 N N     . VAL   A 1 676  ? 181.689 93.491  97.487  1.00 26.26  ? 676  VAL   C N     1 
ATOM   4086 C CA    . VAL   A 1 676  ? 180.999 94.701  97.934  1.00 23.52  ? 676  VAL   C CA    1 
ATOM   4087 C C     . VAL   A 1 676  ? 181.938 95.556  98.771  1.00 25.26  ? 676  VAL   C C     1 
ATOM   4088 O O     . VAL   A 1 676  ? 182.509 95.082  99.750  1.00 26.55  ? 676  VAL   C O     1 
ATOM   4089 C CB    . VAL   A 1 676  ? 179.728 94.355  98.746  1.00 21.64  ? 676  VAL   C CB    1 
ATOM   4090 C CG1   . VAL   A 1 676  ? 180.047 93.359  99.870  1.00 24.24  ? 676  VAL   C CG1   1 
ATOM   4091 C CG2   . VAL   A 1 676  ? 179.137 95.644  99.334  1.00 19.99  ? 676  VAL   C CG2   1 
ATOM   4092 N N     . GLU   A 1 677  ? 182.107 96.815  98.377  1.00 24.60  ? 677  GLU   C N     1 
ATOM   4093 C CA    . GLU   A 1 677  ? 183.029 97.709  99.066  1.00 20.84  ? 677  GLU   C CA    1 
ATOM   4094 C C     . GLU   A 1 677  ? 182.322 98.582  100.095 1.00 17.36  ? 677  GLU   C C     1 
ATOM   4095 O O     . GLU   A 1 677  ? 182.876 98.869  101.160 1.00 19.39  ? 677  GLU   C O     1 
ATOM   4096 C CB    . GLU   A 1 677  ? 183.753 98.597  98.055  1.00 23.35  ? 677  GLU   C CB    1 
ATOM   4097 C CG    . GLU   A 1 677  ? 184.640 97.842  97.075  1.00 31.22  ? 677  GLU   C CG    1 
ATOM   4098 C CD    . GLU   A 1 677  ? 185.308 98.746  96.071  1.00 42.07  ? 677  GLU   C CD    1 
ATOM   4099 O OE1   . GLU   A 1 677  ? 185.056 99.928  96.104  1.00 42.65  ? 677  GLU   C OE1   1 
ATOM   4100 O OE2   . GLU   A 1 677  ? 186.066 98.253  95.270  1.00 37.76  ? 677  GLU   C OE2   1 
ATOM   4101 N N     . SER   A 1 678  ? 181.093 98.982  99.798  1.00 16.80  ? 678  SER   C N     1 
ATOM   4102 C CA    . SER   A 1 678  ? 180.359 99.826  100.732 1.00 13.27  ? 678  SER   C CA    1 
ATOM   4103 C C     . SER   A 1 678  ? 178.902 99.421  100.818 1.00 15.24  ? 678  SER   C C     1 
ATOM   4104 O O     . SER   A 1 678  ? 178.322 98.923  99.849  1.00 19.89  ? 678  SER   C O     1 
ATOM   4105 C CB    . SER   A 1 678  ? 180.459 101.287 100.339 1.00 15.51  ? 678  SER   C CB    1 
ATOM   4106 O OG    . SER   A 1 678  ? 179.820 101.530 99.121  1.00 23.87  ? 678  SER   C OG    1 
ATOM   4107 N N     . LEU   A 1 679  ? 178.322 99.645  101.990 1.00 12.90  ? 679  LEU   C N     1 
ATOM   4108 C CA    . LEU   A 1 679  ? 176.932 99.302  102.253 1.00 12.28  ? 679  LEU   C CA    1 
ATOM   4109 C C     . LEU   A 1 679  ? 176.211 100.390 103.030 1.00 11.55  ? 679  LEU   C C     1 
ATOM   4110 O O     . LEU   A 1 679  ? 176.734 100.902 104.022 1.00 13.96  ? 679  LEU   C O     1 
ATOM   4111 C CB    . LEU   A 1 679  ? 176.877 97.998  103.054 1.00 11.98  ? 679  LEU   C CB    1 
ATOM   4112 C CG    . LEU   A 1 679  ? 175.500 97.519  103.514 1.00 14.61  ? 679  LEU   C CG    1 
ATOM   4113 C CD1   . LEU   A 1 679  ? 174.666 97.077  102.324 1.00 15.96  ? 679  LEU   C CD1   1 
ATOM   4114 C CD2   . LEU   A 1 679  ? 175.701 96.398  104.458 1.00 18.52  ? 679  LEU   C CD2   1 
ATOM   4115 N N     . SER   A 1 680  ? 174.999 100.715 102.594 1.00 11.93  ? 680  SER   C N     1 
ATOM   4116 C CA    . SER   A 1 680  ? 174.150 101.667 103.299 1.00 9.58   ? 680  SER   C CA    1 
ATOM   4117 C C     . SER   A 1 680  ? 172.801 101.043 103.630 1.00 13.44  ? 680  SER   C C     1 
ATOM   4118 O O     . SER   A 1 680  ? 172.083 100.579 102.740 1.00 20.12  ? 680  SER   C O     1 
ATOM   4119 C CB    . SER   A 1 680  ? 173.949 102.913 102.467 1.00 11.49  ? 680  SER   C CB    1 
ATOM   4120 O OG    . SER   A 1 680  ? 173.064 103.795 103.097 1.00 13.72  ? 680  SER   C OG    1 
ATOM   4121 N N     . LEU   A 1 681  ? 172.475 100.991 104.919 1.00 12.39  ? 681  LEU   C N     1 
ATOM   4122 C CA    . LEU   A 1 681  ? 171.231 100.357 105.352 1.00 12.01  ? 681  LEU   C CA    1 
ATOM   4123 C C     . LEU   A 1 681  ? 170.213 101.352 105.884 1.00 15.86  ? 681  LEU   C C     1 
ATOM   4124 O O     . LEU   A 1 681  ? 170.308 101.824 107.017 1.00 20.30  ? 681  LEU   C O     1 
ATOM   4125 C CB    . LEU   A 1 681  ? 171.511 99.310  106.431 1.00 13.90  ? 681  LEU   C CB    1 
ATOM   4126 C CG    . LEU   A 1 681  ? 172.463 98.180  106.048 1.00 15.32  ? 681  LEU   C CG    1 
ATOM   4127 C CD1   . LEU   A 1 681  ? 172.729 97.315  107.264 1.00 17.86  ? 681  LEU   C CD1   1 
ATOM   4128 C CD2   . LEU   A 1 681  ? 171.841 97.360  104.937 1.00 16.60  ? 681  LEU   C CD2   1 
ATOM   4129 N N     . GLY   A 1 682  ? 169.219 101.649 105.062 1.00 18.04  ? 682  GLY   C N     1 
ATOM   4130 C CA    . GLY   A 1 682  ? 168.176 102.602 105.408 1.00 20.83  ? 682  GLY   C CA    1 
ATOM   4131 C C     . GLY   A 1 682  ? 167.034 101.928 106.154 1.00 20.35  ? 682  GLY   C C     1 
ATOM   4132 O O     . GLY   A 1 682  ? 165.964 101.710 105.590 1.00 22.93  ? 682  GLY   C O     1 
ATOM   4133 N N     . PHE   A 1 683  ? 167.257 101.579 107.415 1.00 19.01  ? 683  PHE   C N     1 
ATOM   4134 C CA    . PHE   A 1 683  ? 166.208 100.913 108.179 1.00 19.26  ? 683  PHE   C CA    1 
ATOM   4135 C C     . PHE   A 1 683  ? 164.990 101.825 108.270 1.00 21.20  ? 683  PHE   C C     1 
ATOM   4136 O O     . PHE   A 1 683  ? 165.115 103.000 108.613 1.00 23.49  ? 683  PHE   C O     1 
ATOM   4137 C CB    . PHE   A 1 683  ? 166.689 100.585 109.598 1.00 19.87  ? 683  PHE   C CB    1 
ATOM   4138 C CG    . PHE   A 1 683  ? 167.858 99.627  109.688 1.00 18.43  ? 683  PHE   C CG    1 
ATOM   4139 C CD1   . PHE   A 1 683  ? 168.024 98.579  108.792 1.00 19.84  ? 683  PHE   C CD1   1 
ATOM   4140 C CD2   . PHE   A 1 683  ? 168.804 99.786  110.689 1.00 20.61  ? 683  PHE   C CD2   1 
ATOM   4141 C CE1   . PHE   A 1 683  ? 169.107 97.731  108.900 1.00 21.61  ? 683  PHE   C CE1   1 
ATOM   4142 C CE2   . PHE   A 1 683  ? 169.880 98.936  110.792 1.00 23.67  ? 683  PHE   C CE2   1 
ATOM   4143 C CZ    . PHE   A 1 683  ? 170.029 97.908  109.898 1.00 23.32  ? 683  PHE   C CZ    1 
ATOM   4144 N N     . LEU   A 1 684  ? 163.813 101.282 107.972 1.00 25.17  ? 684  LEU   C N     1 
ATOM   4145 C CA    . LEU   A 1 684  ? 162.576 102.063 108.008 1.00 27.67  ? 684  LEU   C CA    1 
ATOM   4146 C C     . LEU   A 1 684  ? 161.640 101.594 109.119 1.00 32.93  ? 684  LEU   C C     1 
ATOM   4147 O O     . LEU   A 1 684  ? 162.047 100.874 110.035 1.00 34.83  ? 684  LEU   C O     1 
ATOM   4148 C CB    . LEU   A 1 684  ? 161.855 101.980 106.651 1.00 27.41  ? 684  LEU   C CB    1 
ATOM   4149 C CG    . LEU   A 1 684  ? 162.669 102.411 105.411 1.00 28.12  ? 684  LEU   C CG    1 
ATOM   4150 C CD1   . LEU   A 1 684  ? 161.828 102.194 104.164 1.00 28.75  ? 684  LEU   C CD1   1 
ATOM   4151 C CD2   . LEU   A 1 684  ? 163.081 103.873 105.538 1.00 30.94  ? 684  LEU   C CD2   1 
ATOM   4152 N N     . HIS   A 1 685  ? 160.380 102.017 109.045 1.00 32.12  ? 685  HIS   C N     1 
ATOM   4153 C CA    . HIS   A 1 685  ? 159.401 101.674 110.069 1.00 40.90  ? 685  HIS   C CA    1 
ATOM   4154 C C     . HIS   A 1 685  ? 159.085 100.188 110.039 1.00 41.83  ? 685  HIS   C C     1 
ATOM   4155 O O     . HIS   A 1 685  ? 158.127 99.759  109.396 1.00 41.69  ? 685  HIS   C O     1 
ATOM   4156 C CB    . HIS   A 1 685  ? 158.103 102.467 109.858 1.00 45.33  ? 685  HIS   C CB    1 
ATOM   4157 C CG    . HIS   A 1 685  ? 157.108 102.358 110.991 1.00 47.46  ? 685  HIS   C CG    1 
ATOM   4158 N ND1   . HIS   A 1 685  ? 156.533 101.156 111.378 1.00 47.62  ? 685  HIS   C ND1   1 
ATOM   4159 C CD2   . HIS   A 1 685  ? 156.584 103.305 111.803 1.00 49.48  ? 685  HIS   C CD2   1 
ATOM   4160 C CE1   . HIS   A 1 685  ? 155.699 101.382 112.380 1.00 44.01  ? 685  HIS   C CE1   1 
ATOM   4161 N NE2   . HIS   A 1 685  ? 155.716 102.674 112.656 1.00 44.91  ? 685  HIS   C NE2   1 
ATOM   4162 N N     . ASN   A 1 686  ? 159.895 99.403  110.738 1.00 41.67  ? 686  ASN   C N     1 
ATOM   4163 C CA    . ASN   A 1 686  ? 159.707 97.962  110.777 1.00 43.79  ? 686  ASN   C CA    1 
ATOM   4164 C C     . ASN   A 1 686  ? 158.238 97.612  110.996 1.00 45.72  ? 686  ASN   C C     1 
ATOM   4165 O O     . ASN   A 1 686  ? 157.520 98.318  111.709 1.00 46.06  ? 686  ASN   C O     1 
ATOM   4166 C CB    . ASN   A 1 686  ? 160.577 97.329  111.850 1.00 48.36  ? 686  ASN   C CB    1 
ATOM   4167 C CG    . ASN   A 1 686  ? 160.566 95.824  111.789 1.00 49.61  ? 686  ASN   C CG    1 
ATOM   4168 O OD1   . ASN   A 1 686  ? 159.582 95.179  112.171 1.00 45.72  ? 686  ASN   C OD1   1 
ATOM   4169 N ND2   . ASN   A 1 686  ? 161.641 95.255  111.309 1.00 47.74  ? 686  ASN   C ND2   1 
ATOM   4170 N N     . LEU   A 1 725  ? 164.821 100.575 114.357 1.00 31.27  ? 725  LEU   C N     1 
ATOM   4171 C CA    . LEU   A 1 725  ? 165.283 99.293  114.867 1.00 34.71  ? 725  LEU   C CA    1 
ATOM   4172 C C     . LEU   A 1 725  ? 165.141 99.218  116.377 1.00 39.30  ? 725  LEU   C C     1 
ATOM   4173 O O     . LEU   A 1 725  ? 164.108 98.772  116.889 1.00 43.33  ? 725  LEU   C O     1 
ATOM   4174 C CB    . LEU   A 1 725  ? 166.740 99.054  114.430 1.00 30.19  ? 725  LEU   C CB    1 
ATOM   4175 C CG    . LEU   A 1 725  ? 167.453 97.770  114.967 1.00 35.35  ? 725  LEU   C CG    1 
ATOM   4176 C CD1   . LEU   A 1 725  ? 166.653 96.541  114.605 1.00 41.67  ? 725  LEU   C CD1   1 
ATOM   4177 C CD2   . LEU   A 1 725  ? 168.840 97.696  114.365 1.00 32.00  ? 725  LEU   C CD2   1 
ATOM   4178 N N     . THR   A 1 726  ? 166.173 99.643  117.104 1.00 38.03  ? 726  THR   C N     1 
ATOM   4179 C CA    . THR   A 1 726  ? 166.172 99.600  118.563 1.00 38.13  ? 726  THR   C CA    1 
ATOM   4180 C C     . THR   A 1 726  ? 165.706 98.225  119.050 1.00 43.08  ? 726  THR   C C     1 
ATOM   4181 O O     . THR   A 1 726  ? 164.916 98.110  119.987 1.00 43.33  ? 726  THR   C O     1 
ATOM   4182 C CB    . THR   A 1 726  ? 165.260 100.720 119.128 1.00 36.00  ? 726  THR   C CB    1 
ATOM   4183 O OG1   . THR   A 1 726  ? 165.498 101.929 118.399 1.00 37.07  ? 726  THR   C OG1   1 
ATOM   4184 C CG2   . THR   A 1 726  ? 165.560 100.973 120.594 1.00 34.12  ? 726  THR   C CG2   1 
ATOM   4185 N N     . SER   A 1 727  ? 166.204 97.180  118.398 1.00 43.60  ? 727  SER   C N     1 
ATOM   4186 C CA    . SER   A 1 727  ? 165.826 95.805  118.702 1.00 49.06  ? 727  SER   C CA    1 
ATOM   4187 C C     . SER   A 1 727  ? 166.812 94.810  118.102 1.00 47.56  ? 727  SER   C C     1 
ATOM   4188 O O     . SER   A 1 727  ? 167.930 95.166  117.730 1.00 44.66  ? 727  SER   C O     1 
ATOM   4189 C CB    . SER   A 1 727  ? 164.428 95.513  118.187 1.00 48.50  ? 727  SER   C CB    1 
ATOM   4190 O OG    . SER   A 1 727  ? 163.964 94.280  118.674 1.00 54.38  ? 727  SER   C OG    1 
ATOM   4191 N N     . SER   A 1 728  ? 166.386 93.552  118.015 1.00 50.27  ? 728  SER   C N     1 
ATOM   4192 C CA    . SER   A 1 728  ? 167.204 92.462  117.485 1.00 49.92  ? 728  SER   C CA    1 
ATOM   4193 C C     . SER   A 1 728  ? 166.858 92.137  116.035 1.00 51.10  ? 728  SER   C C     1 
ATOM   4194 O O     . SER   A 1 728  ? 167.406 91.202  115.451 1.00 46.26  ? 728  SER   C O     1 
ATOM   4195 C CB    . SER   A 1 728  ? 167.030 91.218  118.337 1.00 50.44  ? 728  SER   C CB    1 
ATOM   4196 O OG    . SER   A 1 728  ? 167.520 91.417  119.641 1.00 50.27  ? 728  SER   C OG    1 
ATOM   4197 N N     . PHE   A 1 729  ? 165.947 92.907  115.448 1.00 52.49  ? 729  PHE   C N     1 
ATOM   4198 C CA    . PHE   A 1 729  ? 165.439 92.632  114.107 1.00 53.41  ? 729  PHE   C CA    1 
ATOM   4199 C C     . PHE   A 1 729  ? 166.545 92.496  113.065 1.00 46.83  ? 729  PHE   C C     1 
ATOM   4200 O O     . PHE   A 1 729  ? 166.462 91.652  112.172 1.00 43.45  ? 729  PHE   C O     1 
ATOM   4201 C CB    . PHE   A 1 729  ? 164.493 93.744  113.646 1.00 52.38  ? 729  PHE   C CB    1 
ATOM   4202 C CG    . PHE   A 1 729  ? 163.179 93.799  114.361 1.00 56.46  ? 729  PHE   C CG    1 
ATOM   4203 C CD1   . PHE   A 1 729  ? 162.794 94.946  115.038 1.00 57.41  ? 729  PHE   C CD1   1 
ATOM   4204 C CD2   . PHE   A 1 729  ? 162.319 92.712  114.355 1.00 58.40  ? 729  PHE   C CD2   1 
ATOM   4205 C CE1   . PHE   A 1 729  ? 161.579 95.006  115.694 1.00 59.77  ? 729  PHE   C CE1   1 
ATOM   4206 C CE2   . PHE   A 1 729  ? 161.105 92.768  115.011 1.00 63.01  ? 729  PHE   C CE2   1 
ATOM   4207 C CZ    . PHE   A 1 729  ? 160.736 93.916  115.682 1.00 64.64  ? 729  PHE   C CZ    1 
ATOM   4208 N N     . CYS   A 1 730  ? 167.569 93.335  113.163 1.00 42.37  ? 730  CYS   C N     1 
ATOM   4209 C CA    . CYS   A 1 730  ? 168.639 93.351  112.177 1.00 37.35  ? 730  CYS   C CA    1 
ATOM   4210 C C     . CYS   A 1 730  ? 169.872 92.591  112.645 1.00 38.41  ? 730  CYS   C C     1 
ATOM   4211 O O     . CYS   A 1 730  ? 170.936 92.697  112.033 1.00 37.15  ? 730  CYS   C O     1 
ATOM   4212 C CB    . CYS   A 1 730  ? 169.039 94.786  111.865 1.00 32.35  ? 730  CYS   C CB    1 
ATOM   4213 S SG    . CYS   A 1 730  ? 167.718 95.748  111.154 1.00 40.50  ? 730  CYS   C SG    1 
ATOM   4214 N N     . ARG   A 1 731  ? 169.740 91.835  113.728 1.00 40.45  ? 731  ARG   C N     1 
ATOM   4215 C CA    . ARG   A 1 731  ? 170.877 91.108  114.275 1.00 38.68  ? 731  ARG   C CA    1 
ATOM   4216 C C     . ARG   A 1 731  ? 171.473 90.150  113.253 1.00 38.07  ? 731  ARG   C C     1 
ATOM   4217 O O     . ARG   A 1 731  ? 172.695 90.024  113.150 1.00 39.22  ? 731  ARG   C O     1 
ATOM   4218 C CB    . ARG   A 1 731  ? 170.470 90.330  115.514 1.00 41.74  ? 731  ARG   C CB    1 
ATOM   4219 C CG    . ARG   A 1 731  ? 171.609 89.627  116.236 1.00 43.45  ? 731  ARG   C CG    1 
ATOM   4220 C CD    . ARG   A 1 731  ? 171.121 88.898  117.433 1.00 46.60  ? 731  ARG   C CD    1 
ATOM   4221 N NE    . ARG   A 1 731  ? 170.566 89.801  118.431 1.00 45.76  ? 731  ARG   C NE    1 
ATOM   4222 C CZ    . ARG   A 1 731  ? 171.284 90.462  119.360 1.00 47.31  ? 731  ARG   C CZ    1 
ATOM   4223 N NH1   . ARG   A 1 731  ? 172.590 90.313  119.418 1.00 41.42  ? 731  ARG   C NH1   1 
ATOM   4224 N NH2   . ARG   A 1 731  ? 170.669 91.259  120.217 1.00 48.70  ? 731  ARG   C NH2   1 
ATOM   4225 N N     . GLY   A 1 732  ? 170.610 89.469  112.503 1.00 39.65  ? 732  GLY   C N     1 
ATOM   4226 C CA    . GLY   A 1 732  ? 171.059 88.502  111.510 1.00 41.24  ? 732  GLY   C CA    1 
ATOM   4227 C C     . GLY   A 1 732  ? 171.866 89.164  110.400 1.00 37.26  ? 732  GLY   C C     1 
ATOM   4228 O O     . GLY   A 1 732  ? 172.833 88.589  109.899 1.00 36.79  ? 732  GLY   C O     1 
ATOM   4229 N N     . LEU   A 1 733  ? 171.465 90.372  110.014 1.00 34.14  ? 733  LEU   C N     1 
ATOM   4230 C CA    . LEU   A 1 733  ? 172.154 91.079  108.946 1.00 31.11  ? 733  LEU   C CA    1 
ATOM   4231 C C     . LEU   A 1 733  ? 173.523 91.542  109.407 1.00 32.41  ? 733  LEU   C C     1 
ATOM   4232 O O     . LEU   A 1 733  ? 174.506 91.420  108.676 1.00 34.78  ? 733  LEU   C O     1 
ATOM   4233 C CB    . LEU   A 1 733  ? 171.319 92.272  108.464 1.00 27.20  ? 733  LEU   C CB    1 
ATOM   4234 C CG    . LEU   A 1 733  ? 171.929 93.137  107.330 1.00 23.61  ? 733  LEU   C CG    1 
ATOM   4235 C CD1   . LEU   A 1 733  ? 172.233 92.278  106.099 1.00 23.91  ? 733  LEU   C CD1   1 
ATOM   4236 C CD2   . LEU   A 1 733  ? 170.937 94.228  106.973 1.00 22.00  ? 733  LEU   C CD2   1 
ATOM   4237 N N     . PHE   A 1 734  ? 173.594 92.063  110.629 1.00 31.63  ? 734  PHE   C N     1 
ATOM   4238 C CA    . PHE   A 1 734  ? 174.864 92.543  111.153 1.00 29.60  ? 734  PHE   C CA    1 
ATOM   4239 C C     . PHE   A 1 734  ? 175.851 91.393  111.302 1.00 32.19  ? 734  PHE   C C     1 
ATOM   4240 O O     . PHE   A 1 734  ? 177.046 91.555  111.042 1.00 34.15  ? 734  PHE   C O     1 
ATOM   4241 C CB    . PHE   A 1 734  ? 174.663 93.267  112.483 1.00 28.24  ? 734  PHE   C CB    1 
ATOM   4242 C CG    . PHE   A 1 734  ? 174.144 94.672  112.325 1.00 23.72  ? 734  PHE   C CG    1 
ATOM   4243 C CD1   . PHE   A 1 734  ? 172.921 95.047  112.858 1.00 27.11  ? 734  PHE   C CD1   1 
ATOM   4244 C CD2   . PHE   A 1 734  ? 174.878 95.619  111.633 1.00 22.53  ? 734  PHE   C CD2   1 
ATOM   4245 C CE1   . PHE   A 1 734  ? 172.452 96.339  112.706 1.00 26.19  ? 734  PHE   C CE1   1 
ATOM   4246 C CE2   . PHE   A 1 734  ? 174.409 96.903  111.478 1.00 21.62  ? 734  PHE   C CE2   1 
ATOM   4247 C CZ    . PHE   A 1 734  ? 173.197 97.264  112.015 1.00 20.83  ? 734  PHE   C CZ    1 
ATOM   4248 N N     . SER   A 1 735  ? 175.347 90.224  111.690 1.00 33.23  ? 735  SER   C N     1 
ATOM   4249 C CA    . SER   A 1 735  ? 176.191 89.046  111.824 1.00 34.65  ? 735  SER   C CA    1 
ATOM   4250 C C     . SER   A 1 735  ? 176.841 88.700  110.488 1.00 35.22  ? 735  SER   C C     1 
ATOM   4251 O O     . SER   A 1 735  ? 178.047 88.462  110.418 1.00 36.85  ? 735  SER   C O     1 
ATOM   4252 C CB    . SER   A 1 735  ? 175.369 87.873  112.321 1.00 41.47  ? 735  SER   C CB    1 
ATOM   4253 O OG    . SER   A 1 735  ? 176.159 86.726  112.463 1.00 46.85  ? 735  SER   C OG    1 
ATOM   4254 N N     . VAL   A 1 736  ? 176.054 88.728  109.413 1.00 35.43  ? 736  VAL   C N     1 
ATOM   4255 C CA    . VAL   A 1 736  ? 176.578 88.445  108.079 1.00 35.21  ? 736  VAL   C CA    1 
ATOM   4256 C C     . VAL   A 1 736  ? 177.657 89.437  107.669 1.00 34.56  ? 736  VAL   C C     1 
ATOM   4257 O O     . VAL   A 1 736  ? 178.694 89.057  107.123 1.00 35.24  ? 736  VAL   C O     1 
ATOM   4258 C CB    . VAL   A 1 736  ? 175.445 88.488  107.034 1.00 31.75  ? 736  VAL   C CB    1 
ATOM   4259 C CG1   . VAL   A 1 736  ? 176.018 88.431  105.618 1.00 30.33  ? 736  VAL   C CG1   1 
ATOM   4260 C CG2   . VAL   A 1 736  ? 174.509 87.321  107.262 1.00 35.04  ? 736  VAL   C CG2   1 
ATOM   4261 N N     . LEU   A 1 737  ? 177.422 90.713  107.935 1.00 33.52  ? 737  LEU   C N     1 
ATOM   4262 C CA    . LEU   A 1 737  ? 178.369 91.744  107.537 1.00 30.63  ? 737  LEU   C CA    1 
ATOM   4263 C C     . LEU   A 1 737  ? 179.716 91.571  108.225 1.00 33.08  ? 737  LEU   C C     1 
ATOM   4264 O O     . LEU   A 1 737  ? 180.757 91.857  107.634 1.00 32.68  ? 737  LEU   C O     1 
ATOM   4265 C CB    . LEU   A 1 737  ? 177.815 93.133  107.876 1.00 24.84  ? 737  LEU   C CB    1 
ATOM   4266 C CG    . LEU   A 1 737  ? 176.529 93.538  107.154 1.00 25.73  ? 737  LEU   C CG    1 
ATOM   4267 C CD1   . LEU   A 1 737  ? 176.078 94.893  107.674 1.00 23.25  ? 737  LEU   C CD1   1 
ATOM   4268 C CD2   . LEU   A 1 737  ? 176.752 93.561  105.669 1.00 27.39  ? 737  LEU   C CD2   1 
ATOM   4269 N N     . SER   A 1 738  ? 179.701 91.084  109.462 1.00 35.28  ? 738  SER   C N     1 
ATOM   4270 C CA    . SER   A 1 738  ? 180.917 90.944  110.262 1.00 35.45  ? 738  SER   C CA    1 
ATOM   4271 C C     . SER   A 1 738  ? 181.911 89.942  109.696 1.00 35.93  ? 738  SER   C C     1 
ATOM   4272 O O     . SER   A 1 738  ? 183.068 89.920  110.110 1.00 38.54  ? 738  SER   C O     1 
ATOM   4273 C CB    . SER   A 1 738  ? 180.575 90.506  111.666 1.00 37.26  ? 738  SER   C CB    1 
ATOM   4274 O OG    . SER   A 1 738  ? 180.254 89.139  111.715 1.00 37.81  ? 738  SER   C OG    1 
ATOM   4275 N N     . THR   A 1 739  ? 181.469 89.091  108.775 1.00 36.42  ? 739  THR   C N     1 
ATOM   4276 C CA    . THR   A 1 739  ? 182.365 88.084  108.229 1.00 38.38  ? 739  THR   C CA    1 
ATOM   4277 C C     . THR   A 1 739  ? 182.837 88.450  106.828 1.00 40.31  ? 739  THR   C C     1 
ATOM   4278 O O     . THR   A 1 739  ? 183.595 87.699  106.210 1.00 40.33  ? 739  THR   C O     1 
ATOM   4279 C CB    . THR   A 1 739  ? 181.695 86.698  108.207 1.00 39.90  ? 739  THR   C CB    1 
ATOM   4280 O OG1   . THR   A 1 739  ? 180.557 86.720  107.340 1.00 39.37  ? 739  THR   C OG1   1 
ATOM   4281 C CG2   . THR   A 1 739  ? 181.239 86.331  109.611 1.00 40.59  ? 739  THR   C CG2   1 
ATOM   4282 N N     . SER   A 1 740  ? 182.384 89.593  106.315 1.00 37.37  ? 740  SER   C N     1 
ATOM   4283 C CA    . SER   A 1 740  ? 182.774 90.014  104.977 1.00 35.83  ? 740  SER   C CA    1 
ATOM   4284 C C     . SER   A 1 740  ? 184.236 90.418  104.944 1.00 34.91  ? 740  SER   C C     1 
ATOM   4285 O O     . SER   A 1 740  ? 184.733 91.077  105.856 1.00 36.21  ? 740  SER   C O     1 
ATOM   4286 C CB    . SER   A 1 740  ? 181.920 91.167  104.500 1.00 34.03  ? 740  SER   C CB    1 
ATOM   4287 O OG    . SER   A 1 740  ? 182.365 91.623  103.246 1.00 32.87  ? 740  SER   C OG    1 
ATOM   4288 N N     . GLN   A 1 741  ? 184.928 90.027  103.885 1.00 33.84  ? 741  GLN   C N     1 
ATOM   4289 C CA    . GLN   A 1 741  ? 186.329 90.391  103.748 1.00 34.61  ? 741  GLN   C CA    1 
ATOM   4290 C C     . GLN   A 1 741  ? 186.536 91.508  102.736 1.00 33.26  ? 741  GLN   C C     1 
ATOM   4291 O O     . GLN   A 1 741  ? 187.669 91.904  102.465 1.00 35.42  ? 741  GLN   C O     1 
ATOM   4292 C CB    . GLN   A 1 741  ? 187.157 89.159  103.386 1.00 36.98  ? 741  GLN   C CB    1 
ATOM   4293 C CG    . GLN   A 1 741  ? 187.033 88.047  104.415 1.00 42.29  ? 741  GLN   C CG    1 
ATOM   4294 C CD    . GLN   A 1 741  ? 187.391 88.537  105.805 1.00 42.66  ? 741  GLN   C CD    1 
ATOM   4295 O OE1   . GLN   A 1 741  ? 188.524 88.963  106.065 1.00 40.49  ? 741  GLN   C OE1   1 
ATOM   4296 N NE2   . GLN   A 1 741  ? 186.414 88.509  106.706 1.00 42.26  ? 741  GLN   C NE2   1 
ATOM   4297 N N     . SER   A 1 742  ? 185.442 92.008  102.165 1.00 28.57  ? 742  SER   C N     1 
ATOM   4298 C CA    . SER   A 1 742  ? 185.539 93.054  101.151 1.00 26.28  ? 742  SER   C CA    1 
ATOM   4299 C C     . SER   A 1 742  ? 184.911 94.376  101.591 1.00 23.76  ? 742  SER   C C     1 
ATOM   4300 O O     . SER   A 1 742  ? 185.225 95.429  101.037 1.00 24.63  ? 742  SER   C O     1 
ATOM   4301 C CB    . SER   A 1 742  ? 184.898 92.584  99.861  1.00 30.97  ? 742  SER   C CB    1 
ATOM   4302 O OG    . SER   A 1 742  ? 185.602 91.496  99.320  1.00 34.71  ? 742  SER   C OG    1 
ATOM   4303 N N     . LEU   A 1 743  ? 184.028 94.328  102.585 1.00 22.68  ? 743  LEU   C N     1 
ATOM   4304 C CA    . LEU   A 1 743  ? 183.337 95.536  103.021 1.00 18.29  ? 743  LEU   C CA    1 
ATOM   4305 C C     . LEU   A 1 743  ? 184.298 96.464  103.741 1.00 19.05  ? 743  LEU   C C     1 
ATOM   4306 O O     . LEU   A 1 743  ? 184.971 96.056  104.684 1.00 21.66  ? 743  LEU   C O     1 
ATOM   4307 C CB    . LEU   A 1 743  ? 182.166 95.176  103.955 1.00 16.48  ? 743  LEU   C CB    1 
ATOM   4308 C CG    . LEU   A 1 743  ? 181.300 96.357  104.479 1.00 12.51  ? 743  LEU   C CG    1 
ATOM   4309 C CD1   . LEU   A 1 743  ? 180.544 96.999  103.318 1.00 15.98  ? 743  LEU   C CD1   1 
ATOM   4310 C CD2   . LEU   A 1 743  ? 180.325 95.840  105.533 1.00 15.37  ? 743  LEU   C CD2   1 
ATOM   4311 N N     . THR   A 1 744  ? 184.355 97.718  103.309 1.00 17.17  ? 744  THR   C N     1 
ATOM   4312 C CA    . THR   A 1 744  ? 185.240 98.694  103.925 1.00 11.41  ? 744  THR   C CA    1 
ATOM   4313 C C     . THR   A 1 744  ? 184.467 99.803  104.625 1.00 10.94  ? 744  THR   C C     1 
ATOM   4314 O O     . THR   A 1 744  ? 184.867 100.268 105.698 1.00 15.55  ? 744  THR   C O     1 
ATOM   4315 C CB    . THR   A 1 744  ? 186.182 99.310  102.873 1.00 12.93  ? 744  THR   C CB    1 
ATOM   4316 O OG1   . THR   A 1 744  ? 186.986 98.278  102.288 1.00 17.69  ? 744  THR   C OG1   1 
ATOM   4317 C CG2   . THR   A 1 744  ? 187.085 100.340 103.508 1.00 14.67  ? 744  THR   C CG2   1 
ATOM   4318 N N     . GLU   A 1 745  ? 183.370 100.241 104.016 1.00 10.01  ? 745  GLU   C N     1 
ATOM   4319 C CA    . GLU   A 1 745  ? 182.605 101.360 104.558 1.00 7.80   ? 745  GLU   C CA    1 
ATOM   4320 C C     . GLU   A 1 745  ? 181.165 100.994 104.891 1.00 8.97   ? 745  GLU   C C     1 
ATOM   4321 O O     . GLU   A 1 745  ? 180.429 100.489 104.042 1.00 15.78  ? 745  GLU   C O     1 
ATOM   4322 C CB    . GLU   A 1 745  ? 182.621 102.519 103.570 1.00 10.34  ? 745  GLU   C CB    1 
ATOM   4323 C CG    . GLU   A 1 745  ? 181.841 103.736 104.010 1.00 10.66  ? 745  GLU   C CG    1 
ATOM   4324 C CD    . GLU   A 1 745  ? 181.965 104.873 103.047 1.00 12.60  ? 745  GLU   C CD    1 
ATOM   4325 O OE1   . GLU   A 1 745  ? 182.998 104.997 102.428 1.00 14.09  ? 745  GLU   C OE1   1 
ATOM   4326 O OE2   . GLU   A 1 745  ? 181.028 105.622 102.921 1.00 11.63  ? 745  GLU   C OE2   1 
ATOM   4327 N N     . LEU   A 1 746  ? 180.760 101.273 106.127 1.00 6.82   ? 746  LEU   C N     1 
ATOM   4328 C CA    . LEU   A 1 746  ? 179.397 100.986 106.563 1.00 6.51   ? 746  LEU   C CA    1 
ATOM   4329 C C     . LEU   A 1 746  ? 178.661 102.258 106.976 1.00 6.45   ? 746  LEU   C C     1 
ATOM   4330 O O     . LEU   A 1 746  ? 179.082 102.963 107.894 1.00 9.01   ? 746  LEU   C O     1 
ATOM   4331 C CB    . LEU   A 1 746  ? 179.422 99.977  107.723 1.00 7.42   ? 746  LEU   C CB    1 
ATOM   4332 C CG    . LEU   A 1 746  ? 178.062 99.619  108.366 1.00 7.17   ? 746  LEU   C CG    1 
ATOM   4333 C CD1   . LEU   A 1 746  ? 177.154 98.944  107.336 1.00 9.91   ? 746  LEU   C CD1   1 
ATOM   4334 C CD2   . LEU   A 1 746  ? 178.300 98.688  109.547 1.00 8.90   ? 746  LEU   C CD2   1 
ATOM   4335 N N     . ASP   A 1 747  ? 177.562 102.548 106.285 1.00 7.05   ? 747  ASP   C N     1 
ATOM   4336 C CA    . ASP   A 1 747  ? 176.780 103.755 106.534 1.00 5.83   ? 747  ASP   C CA    1 
ATOM   4337 C C     . ASP   A 1 747  ? 175.430 103.453 107.180 1.00 8.55   ? 747  ASP   C C     1 
ATOM   4338 O O     . ASP   A 1 747  ? 174.563 102.819 106.573 1.00 13.61  ? 747  ASP   C O     1 
ATOM   4339 C CB    . ASP   A 1 747  ? 176.576 104.538 105.237 1.00 7.26   ? 747  ASP   C CB    1 
ATOM   4340 C CG    . ASP   A 1 747  ? 175.854 105.864 105.447 1.00 9.64   ? 747  ASP   C CG    1 
ATOM   4341 O OD1   . ASP   A 1 747  ? 175.267 106.046 106.494 1.00 12.28  ? 747  ASP   C OD1   1 
ATOM   4342 O OD2   . ASP   A 1 747  ? 175.897 106.687 104.561 1.00 7.78   ? 747  ASP   C OD2   1 
ATOM   4343 N N     . LEU   A 1 748  ? 175.281 103.861 108.436 1.00 7.36   ? 748  LEU   C N     1 
ATOM   4344 C CA    . LEU   A 1 748  ? 174.061 103.615 109.190 1.00 7.33   ? 748  LEU   C CA    1 
ATOM   4345 C C     . LEU   A 1 748  ? 173.435 104.919 109.659 1.00 9.26   ? 748  LEU   C C     1 
ATOM   4346 O O     . LEU   A 1 748  ? 172.766 104.951 110.690 1.00 13.04  ? 748  LEU   C O     1 
ATOM   4347 C CB    . LEU   A 1 748  ? 174.362 102.738 110.402 1.00 7.29   ? 748  LEU   C CB    1 
ATOM   4348 C CG    . LEU   A 1 748  ? 174.882 101.347 110.101 1.00 9.79   ? 748  LEU   C CG    1 
ATOM   4349 C CD1   . LEU   A 1 748  ? 175.456 100.774 111.352 1.00 12.78  ? 748  LEU   C CD1   1 
ATOM   4350 C CD2   . LEU   A 1 748  ? 173.753 100.471 109.582 1.00 12.02  ? 748  LEU   C CD2   1 
ATOM   4351 N N     . SER   A 1 749  ? 173.659 105.988 108.908 1.00 8.52   ? 749  SER   C N     1 
ATOM   4352 C CA    . SER   A 1 749  ? 173.144 107.305 109.266 1.00 8.17   ? 749  SER   C CA    1 
ATOM   4353 C C     . SER   A 1 749  ? 171.652 107.458 108.995 1.00 11.62  ? 749  SER   C C     1 
ATOM   4354 O O     . SER   A 1 749  ? 171.059 106.701 108.227 1.00 18.62  ? 749  SER   C O     1 
ATOM   4355 C CB    . SER   A 1 749  ? 173.905 108.377 108.513 1.00 8.98   ? 749  SER   C CB    1 
ATOM   4356 O OG    . SER   A 1 749  ? 175.234 108.468 108.963 1.00 12.37  ? 749  SER   C OG    1 
ATOM   4357 N N     . ASP   A 1 750  ? 171.057 108.461 109.631 1.00 11.55  ? 750  ASP   C N     1 
ATOM   4358 C CA    . ASP   A 1 750  ? 169.672 108.865 109.402 1.00 11.92  ? 750  ASP   C CA    1 
ATOM   4359 C C     . ASP   A 1 750  ? 168.638 107.753 109.570 1.00 15.33  ? 750  ASP   C C     1 
ATOM   4360 O O     . ASP   A 1 750  ? 167.691 107.652 108.788 1.00 19.94  ? 750  ASP   C O     1 
ATOM   4361 C CB    . ASP   A 1 750  ? 169.541 109.485 108.012 1.00 14.05  ? 750  ASP   C CB    1 
ATOM   4362 C CG    . ASP   A 1 750  ? 170.323 110.784 107.886 1.00 18.03  ? 750  ASP   C CG    1 
ATOM   4363 O OD1   . ASP   A 1 750  ? 170.214 111.609 108.765 1.00 18.30  ? 750  ASP   C OD1   1 
ATOM   4364 O OD2   . ASP   A 1 750  ? 171.032 110.939 106.921 1.00 20.07  ? 750  ASP   C OD2   1 
ATOM   4365 N N     . ASN   A 1 751  ? 168.792 106.950 110.611 1.00 14.71  ? 751  ASN   C N     1 
ATOM   4366 C CA    . ASN   A 1 751  ? 167.807 105.928 110.950 1.00 15.77  ? 751  ASN   C CA    1 
ATOM   4367 C C     . ASN   A 1 751  ? 167.815 105.710 112.455 1.00 17.82  ? 751  ASN   C C     1 
ATOM   4368 O O     . ASN   A 1 751  ? 168.768 106.087 113.134 1.00 19.57  ? 751  ASN   C O     1 
ATOM   4369 C CB    . ASN   A 1 751  ? 168.066 104.641 110.194 1.00 15.63  ? 751  ASN   C CB    1 
ATOM   4370 C CG    . ASN   A 1 751  ? 169.325 103.996 110.600 1.00 15.33  ? 751  ASN   C CG    1 
ATOM   4371 O OD1   . ASN   A 1 751  ? 169.341 103.145 111.498 1.00 17.59  ? 751  ASN   C OD1   1 
ATOM   4372 N ND2   . ASN   A 1 751  ? 170.393 104.377 109.975 1.00 16.36  ? 751  ASN   C ND2   1 
ATOM   4373 N N     . SER   A 1 752  ? 166.762 105.099 112.983 1.00 19.75  ? 752  SER   C N     1 
ATOM   4374 C CA    . SER   A 1 752  ? 166.615 104.964 114.430 1.00 18.65  ? 752  SER   C CA    1 
ATOM   4375 C C     . SER   A 1 752  ? 167.458 103.852 115.036 1.00 20.84  ? 752  SER   C C     1 
ATOM   4376 O O     . SER   A 1 752  ? 166.932 102.898 115.612 1.00 27.33  ? 752  SER   C O     1 
ATOM   4377 C CB    . SER   A 1 752  ? 165.158 104.731 114.777 1.00 30.26  ? 752  SER   C CB    1 
ATOM   4378 O OG    . SER   A 1 752  ? 164.368 105.821 114.391 1.00 33.69  ? 752  SER   C OG    1 
ATOM   4379 N N     . LEU   A 1 753  ? 168.771 104.005 114.955 1.00 19.48  ? 753  LEU   C N     1 
ATOM   4380 C CA    . LEU   A 1 753  ? 169.692 103.052 115.557 1.00 19.25  ? 753  LEU   C CA    1 
ATOM   4381 C C     . LEU   A 1 753  ? 169.907 103.433 117.009 1.00 20.74  ? 753  LEU   C C     1 
ATOM   4382 O O     . LEU   A 1 753  ? 170.989 103.875 117.393 1.00 25.93  ? 753  LEU   C O     1 
ATOM   4383 C CB    . LEU   A 1 753  ? 171.040 103.053 114.813 1.00 19.07  ? 753  LEU   C CB    1 
ATOM   4384 C CG    . LEU   A 1 753  ? 172.062 101.957 115.211 1.00 19.35  ? 753  LEU   C CG    1 
ATOM   4385 C CD1   . LEU   A 1 753  ? 171.576 100.597 114.736 1.00 21.69  ? 753  LEU   C CD1   1 
ATOM   4386 C CD2   . LEU   A 1 753  ? 173.413 102.301 114.600 1.00 19.71  ? 753  LEU   C CD2   1 
ATOM   4387 N N     . GLY   A 1 754  ? 168.866 103.262 117.813 1.00 19.55  ? 754  GLY   C N     1 
ATOM   4388 C CA    . GLY   A 1 754  ? 168.903 103.690 119.204 1.00 21.85  ? 754  GLY   C CA    1 
ATOM   4389 C C     . GLY   A 1 754  ? 169.964 102.914 119.963 1.00 23.99  ? 754  GLY   C C     1 
ATOM   4390 O O     . GLY   A 1 754  ? 170.520 101.945 119.443 1.00 25.32  ? 754  GLY   C O     1 
ATOM   4391 N N     . ASP   A 1 755  ? 170.241 103.331 121.197 1.00 21.91  ? 755  ASP   C N     1 
ATOM   4392 C CA    . ASP   A 1 755  ? 171.325 102.732 121.961 1.00 20.77  ? 755  ASP   C CA    1 
ATOM   4393 C C     . ASP   A 1 755  ? 171.371 101.194 121.888 1.00 27.57  ? 755  ASP   C C     1 
ATOM   4394 O O     . ASP   A 1 755  ? 172.446 100.653 121.631 1.00 29.01  ? 755  ASP   C O     1 
ATOM   4395 C CB    . ASP   A 1 755  ? 171.320 103.225 123.417 1.00 19.73  ? 755  ASP   C CB    1 
ATOM   4396 C CG    . ASP   A 1 755  ? 171.769 104.669 123.548 1.00 25.14  ? 755  ASP   C CG    1 
ATOM   4397 O OD1   . ASP   A 1 755  ? 172.262 105.234 122.595 1.00 24.51  ? 755  ASP   C OD1   1 
ATOM   4398 O OD2   . ASP   A 1 755  ? 171.613 105.198 124.616 1.00 25.44  ? 755  ASP   C OD2   1 
ATOM   4399 N N     . PRO   A 1 756  ? 170.258 100.452 122.093 1.00 26.54  ? 756  PRO   C N     1 
ATOM   4400 C CA    . PRO   A 1 756  ? 170.193 99.005  121.985 1.00 24.75  ? 756  PRO   C CA    1 
ATOM   4401 C C     . PRO   A 1 756  ? 170.747 98.494  120.654 1.00 27.42  ? 756  PRO   C C     1 
ATOM   4402 O O     . PRO   A 1 756  ? 171.349 97.420  120.597 1.00 29.70  ? 756  PRO   C O     1 
ATOM   4403 C CB    . PRO   A 1 756  ? 168.692 98.738  122.109 1.00 27.15  ? 756  PRO   C CB    1 
ATOM   4404 C CG    . PRO   A 1 756  ? 168.188 99.870  122.953 1.00 27.59  ? 756  PRO   C CG    1 
ATOM   4405 C CD    . PRO   A 1 756  ? 168.986 101.071 122.501 1.00 27.19  ? 756  PRO   C CD    1 
ATOM   4406 N N     . GLY   A 1 757  ? 170.534 99.264  119.584 1.00 27.14  ? 757  GLY   C N     1 
ATOM   4407 C CA    . GLY   A 1 757  ? 171.004 98.871  118.264 1.00 27.06  ? 757  GLY   C CA    1 
ATOM   4408 C C     . GLY   A 1 757  ? 172.497 99.108  118.150 1.00 25.59  ? 757  GLY   C C     1 
ATOM   4409 O O     . GLY   A 1 757  ? 173.212 98.356  117.481 1.00 27.39  ? 757  GLY   C O     1 
ATOM   4410 N N     . MET   A 1 758  ? 172.966 100.151 118.823 1.00 24.19  ? 758  MET   C N     1 
ATOM   4411 C CA    . MET   A 1 758  ? 174.374 100.496 118.790 1.00 23.48  ? 758  MET   C CA    1 
ATOM   4412 C C     . MET   A 1 758  ? 175.178 99.491  119.596 1.00 25.60  ? 758  MET   C C     1 
ATOM   4413 O O     . MET   A 1 758  ? 176.323 99.197  119.259 1.00 27.48  ? 758  MET   C O     1 
ATOM   4414 C CB    . MET   A 1 758  ? 174.593 101.909 119.308 1.00 22.55  ? 758  MET   C CB    1 
ATOM   4415 C CG    . MET   A 1 758  ? 175.985 102.451 119.050 1.00 19.72  ? 758  MET   C CG    1 
ATOM   4416 S SD    . MET   A 1 758  ? 176.325 102.652 117.303 1.00 20.82  ? 758  MET   C SD    1 
ATOM   4417 C CE    . MET   A 1 758  ? 177.982 101.985 117.202 1.00 16.76  ? 758  MET   C CE    1 
ATOM   4418 N N     . ARG   A 1 759  ? 174.567 98.936  120.642 1.00 25.83  ? 759  ARG   C N     1 
ATOM   4419 C CA    . ARG   A 1 759  ? 175.235 97.911  121.432 1.00 24.11  ? 759  ARG   C CA    1 
ATOM   4420 C C     . ARG   A 1 759  ? 175.481 96.665  120.589 1.00 27.78  ? 759  ARG   C C     1 
ATOM   4421 O O     . ARG   A 1 759  ? 176.572 96.094  120.622 1.00 29.60  ? 759  ARG   C O     1 
ATOM   4422 C CB    . ARG   A 1 759  ? 174.426 97.533  122.657 1.00 24.91  ? 759  ARG   C CB    1 
ATOM   4423 C CG    . ARG   A 1 759  ? 175.106 96.511  123.553 1.00 28.18  ? 759  ARG   C CG    1 
ATOM   4424 C CD    . ARG   A 1 759  ? 174.336 96.244  124.784 1.00 29.67  ? 759  ARG   C CD    1 
ATOM   4425 N NE    . ARG   A 1 759  ? 174.991 95.240  125.603 1.00 30.39  ? 759  ARG   C NE    1 
ATOM   4426 C CZ    . ARG   A 1 759  ? 174.516 94.758  126.765 1.00 31.94  ? 759  ARG   C CZ    1 
ATOM   4427 N NH1   . ARG   A 1 759  ? 173.371 95.190  127.245 1.00 36.61  ? 759  ARG   C NH1   1 
ATOM   4428 N NH2   . ARG   A 1 759  ? 175.209 93.845  127.422 1.00 34.12  ? 759  ARG   C NH2   1 
ATOM   4429 N N     . VAL   A 1 760  ? 174.476 96.264  119.807 1.00 27.85  ? 760  VAL   C N     1 
ATOM   4430 C CA    . VAL   A 1 760  ? 174.611 95.095  118.940 1.00 27.66  ? 760  VAL   C CA    1 
ATOM   4431 C C     . VAL   A 1 760  ? 175.706 95.322  117.910 1.00 27.77  ? 760  VAL   C C     1 
ATOM   4432 O O     . VAL   A 1 760  ? 176.527 94.438  117.653 1.00 29.53  ? 760  VAL   C O     1 
ATOM   4433 C CB    . VAL   A 1 760  ? 173.283 94.789  118.219 1.00 27.60  ? 760  VAL   C CB    1 
ATOM   4434 C CG1   . VAL   A 1 760  ? 173.485 93.694  117.162 1.00 28.47  ? 760  VAL   C CG1   1 
ATOM   4435 C CG2   . VAL   A 1 760  ? 172.252 94.352  119.238 1.00 33.19  ? 760  VAL   C CG2   1 
ATOM   4436 N N     . LEU   A 1 761  ? 175.726 96.514  117.326 1.00 24.93  ? 761  LEU   C N     1 
ATOM   4437 C CA    . LEU   A 1 761  ? 176.752 96.848  116.353 1.00 22.38  ? 761  LEU   C CA    1 
ATOM   4438 C C     . LEU   A 1 761  ? 178.134 96.869  116.996 1.00 26.04  ? 761  LEU   C C     1 
ATOM   4439 O O     . LEU   A 1 761  ? 179.090 96.343  116.430 1.00 26.48  ? 761  LEU   C O     1 
ATOM   4440 C CB    . LEU   A 1 761  ? 176.448 98.202  115.713 1.00 18.76  ? 761  LEU   C CB    1 
ATOM   4441 C CG    . LEU   A 1 761  ? 177.461 98.722  114.688 1.00 17.62  ? 761  LEU   C CG    1 
ATOM   4442 C CD1   . LEU   A 1 761  ? 177.597 97.750  113.522 1.00 19.38  ? 761  LEU   C CD1   1 
ATOM   4443 C CD2   . LEU   A 1 761  ? 176.989 100.060 114.201 1.00 17.28  ? 761  LEU   C CD2   1 
ATOM   4444 N N     . CYS   A 1 762  ? 178.245 97.451  118.185 1.00 25.24  ? 762  CYS   C N     1 
ATOM   4445 C CA    . CYS   A 1 762  ? 179.535 97.516  118.857 1.00 22.02  ? 762  CYS   C CA    1 
ATOM   4446 C C     . CYS   A 1 762  ? 180.094 96.132  119.144 1.00 26.29  ? 762  CYS   C C     1 
ATOM   4447 O O     . CYS   A 1 762  ? 181.299 95.917  119.050 1.00 25.81  ? 762  CYS   C O     1 
ATOM   4448 C CB    . CYS   A 1 762  ? 179.434 98.302  120.153 1.00 21.52  ? 762  CYS   C CB    1 
ATOM   4449 S SG    . CYS   A 1 762  ? 179.193 100.061 119.901 1.00 29.03  ? 762  CYS   C SG    1 
ATOM   4450 N N     . GLU   A 1 763  ? 179.226 95.183  119.482 1.00 28.87  ? 763  GLU   C N     1 
ATOM   4451 C CA    . GLU   A 1 763  ? 179.672 93.808  119.671 1.00 29.77  ? 763  GLU   C CA    1 
ATOM   4452 C C     . GLU   A 1 763  ? 180.116 93.217  118.334 1.00 29.01  ? 763  GLU   C C     1 
ATOM   4453 O O     . GLU   A 1 763  ? 181.136 92.533  118.244 1.00 31.93  ? 763  GLU   C O     1 
ATOM   4454 C CB    . GLU   A 1 763  ? 178.547 92.959  120.270 1.00 30.41  ? 763  GLU   C CB    1 
ATOM   4455 C CG    . GLU   A 1 763  ? 178.193 93.301  121.718 1.00 35.54  ? 763  GLU   C CG    1 
ATOM   4456 C CD    . GLU   A 1 763  ? 176.949 92.599  122.202 1.00 40.99  ? 763  GLU   C CD    1 
ATOM   4457 O OE1   . GLU   A 1 763  ? 176.254 92.039  121.387 1.00 38.94  ? 763  GLU   C OE1   1 
ATOM   4458 O OE2   . GLU   A 1 763  ? 176.694 92.619  123.385 1.00 42.97  ? 763  GLU   C OE2   1 
ATOM   4459 N N     . THR   A 1 764  ? 179.358 93.523  117.288 1.00 27.97  ? 764  THR   C N     1 
ATOM   4460 C CA    . THR   A 1 764  ? 179.610 93.021  115.942 1.00 27.01  ? 764  THR   C CA    1 
ATOM   4461 C C     . THR   A 1 764  ? 180.954 93.510  115.397 1.00 29.06  ? 764  THR   C C     1 
ATOM   4462 O O     . THR   A 1 764  ? 181.696 92.757  114.761 1.00 31.48  ? 764  THR   C O     1 
ATOM   4463 C CB    . THR   A 1 764  ? 178.470 93.457  115.000 1.00 27.48  ? 764  THR   C CB    1 
ATOM   4464 O OG1   . THR   A 1 764  ? 177.221 92.954  115.497 1.00 29.09  ? 764  THR   C OG1   1 
ATOM   4465 C CG2   . THR   A 1 764  ? 178.689 92.923  113.621 1.00 28.80  ? 764  THR   C CG2   1 
ATOM   4466 N N     . LEU   A 1 765  ? 181.272 94.772  115.663 1.00 27.84  ? 765  LEU   C N     1 
ATOM   4467 C CA    . LEU   A 1 765  ? 182.485 95.406  115.153 1.00 24.00  ? 765  LEU   C CA    1 
ATOM   4468 C C     . LEU   A 1 765  ? 183.761 94.869  115.790 1.00 25.20  ? 765  LEU   C C     1 
ATOM   4469 O O     . LEU   A 1 765  ? 184.861 95.217  115.361 1.00 26.98  ? 765  LEU   C O     1 
ATOM   4470 C CB    . LEU   A 1 765  ? 182.426 96.921  115.385 1.00 19.76  ? 765  LEU   C CB    1 
ATOM   4471 C CG    . LEU   A 1 765  ? 181.367 97.710  114.590 1.00 19.24  ? 765  LEU   C CG    1 
ATOM   4472 C CD1   . LEU   A 1 765  ? 181.277 99.110  115.160 1.00 20.10  ? 765  LEU   C CD1   1 
ATOM   4473 C CD2   . LEU   A 1 765  ? 181.745 97.763  113.123 1.00 19.42  ? 765  LEU   C CD2   1 
ATOM   4474 N N     . GLN   A 1 766  ? 183.633 94.050  116.831 1.00 25.95  ? 766  GLN   C N     1 
ATOM   4475 C CA    . GLN   A 1 766  ? 184.807 93.516  117.509 1.00 27.70  ? 766  GLN   C CA    1 
ATOM   4476 C C     . GLN   A 1 766  ? 185.252 92.181  116.926 1.00 31.98  ? 766  GLN   C C     1 
ATOM   4477 O O     . GLN   A 1 766  ? 186.248 91.609  117.369 1.00 34.53  ? 766  GLN   C O     1 
ATOM   4478 C CB    . GLN   A 1 766  ? 184.540 93.382  119.008 1.00 28.45  ? 766  GLN   C CB    1 
ATOM   4479 C CG    . GLN   A 1 766  ? 184.358 94.713  119.697 1.00 26.97  ? 766  GLN   C CG    1 
ATOM   4480 C CD    . GLN   A 1 766  ? 183.976 94.589  121.149 1.00 25.10  ? 766  GLN   C CD    1 
ATOM   4481 O OE1   . GLN   A 1 766  ? 184.757 94.127  121.984 1.00 26.42  ? 766  GLN   C OE1   1 
ATOM   4482 N NE2   . GLN   A 1 766  ? 182.759 95.004  121.459 1.00 24.18  ? 766  GLN   C NE2   1 
ATOM   4483 N N     . HIS   A 1 767  ? 184.523 91.680  115.932 1.00 33.24  ? 767  HIS   C N     1 
ATOM   4484 C CA    . HIS   A 1 767  ? 184.892 90.415  115.307 1.00 36.10  ? 767  HIS   C CA    1 
ATOM   4485 C C     . HIS   A 1 767  ? 186.278 90.558  114.656 1.00 37.90  ? 767  HIS   C C     1 
ATOM   4486 O O     . HIS   A 1 767  ? 186.518 91.530  113.937 1.00 39.45  ? 767  HIS   C O     1 
ATOM   4487 C CB    . HIS   A 1 767  ? 183.859 90.022  114.239 1.00 38.41  ? 767  HIS   C CB    1 
ATOM   4488 C CG    . HIS   A 1 767  ? 183.970 88.601  113.772 1.00 41.74  ? 767  HIS   C CG    1 
ATOM   4489 N ND1   . HIS   A 1 767  ? 185.007 88.154  112.981 1.00 42.94  ? 767  HIS   C ND1   1 
ATOM   4490 C CD2   . HIS   A 1 767  ? 183.169 87.532  113.983 1.00 42.19  ? 767  HIS   C CD2   1 
ATOM   4491 C CE1   . HIS   A 1 767  ? 184.838 86.867  112.728 1.00 45.44  ? 767  HIS   C CE1   1 
ATOM   4492 N NE2   . HIS   A 1 767  ? 183.731 86.468  113.325 1.00 43.96  ? 767  HIS   C NE2   1 
ATOM   4493 N N     . PRO   A 1 768  ? 187.197 89.604  114.864 1.00 37.77  ? 768  PRO   C N     1 
ATOM   4494 C CA    . PRO   A 1 768  ? 188.535 89.559  114.296 1.00 39.80  ? 768  PRO   C CA    1 
ATOM   4495 C C     . PRO   A 1 768  ? 188.576 89.750  112.782 1.00 42.29  ? 768  PRO   C C     1 
ATOM   4496 O O     . PRO   A 1 768  ? 189.560 90.259  112.246 1.00 41.66  ? 768  PRO   C O     1 
ATOM   4497 C CB    . PRO   A 1 768  ? 188.993 88.147  114.676 1.00 39.42  ? 768  PRO   C CB    1 
ATOM   4498 C CG    . PRO   A 1 768  ? 188.266 87.845  115.957 1.00 40.03  ? 768  PRO   C CG    1 
ATOM   4499 C CD    . PRO   A 1 768  ? 186.910 88.501  115.803 1.00 38.95  ? 768  PRO   C CD    1 
ATOM   4500 N N     . GLY   A 1 769  ? 187.521 89.329  112.091 1.00 41.83  ? 769  GLY   C N     1 
ATOM   4501 C CA    . GLY   A 1 769  ? 187.474 89.417  110.635 1.00 41.61  ? 769  GLY   C CA    1 
ATOM   4502 C C     . GLY   A 1 769  ? 186.589 90.549  110.123 1.00 39.76  ? 769  GLY   C C     1 
ATOM   4503 O O     . GLY   A 1 769  ? 186.193 90.536  108.960 1.00 39.38  ? 769  GLY   C O     1 
ATOM   4504 N N     . CYS   A 1 770  ? 186.242 91.495  110.996 1.00 37.21  ? 770  CYS   C N     1 
ATOM   4505 C CA    . CYS   A 1 770  ? 185.318 92.578  110.650 1.00 32.28  ? 770  CYS   C CA    1 
ATOM   4506 C C     . CYS   A 1 770  ? 185.746 93.379  109.417 1.00 32.79  ? 770  CYS   C C     1 
ATOM   4507 O O     . CYS   A 1 770  ? 184.981 93.504  108.464 1.00 33.55  ? 770  CYS   C O     1 
ATOM   4508 C CB    . CYS   A 1 770  ? 185.168 93.532  111.830 1.00 29.25  ? 770  CYS   C CB    1 
ATOM   4509 S SG    . CYS   A 1 770  ? 184.033 94.883  111.530 1.00 34.88  ? 770  CYS   C SG    1 
ATOM   4510 N N     . ASN   A 1 771  ? 186.959 93.928  109.447 1.00 32.39  ? 771  ASN   C N     1 
ATOM   4511 C CA    . ASN   A 1 771  ? 187.541 94.686  108.328 1.00 29.29  ? 771  ASN   C CA    1 
ATOM   4512 C C     . ASN   A 1 771  ? 186.855 96.009  107.974 1.00 23.29  ? 771  ASN   C C     1 
ATOM   4513 O O     . ASN   A 1 771  ? 187.165 96.596  106.938 1.00 21.80  ? 771  ASN   C O     1 
ATOM   4514 C CB    . ASN   A 1 771  ? 187.592 93.831  107.074 1.00 29.97  ? 771  ASN   C CB    1 
ATOM   4515 C CG    . ASN   A 1 771  ? 188.456 92.640  107.214 1.00 39.52  ? 771  ASN   C CG    1 
ATOM   4516 O OD1   . ASN   A 1 771  ? 189.630 92.739  107.596 1.00 39.22  ? 771  ASN   C OD1   1 
ATOM   4517 N ND2   . ASN   A 1 771  ? 187.905 91.504  106.910 1.00 40.23  ? 771  ASN   C ND2   1 
ATOM   4518 N N     . ILE   A 1 772  ? 185.971 96.515  108.822 1.00 21.77  ? 772  ILE   C N     1 
ATOM   4519 C CA    . ILE   A 1 772  ? 185.363 97.812  108.528 1.00 15.23  ? 772  ILE   C CA    1 
ATOM   4520 C C     . ILE   A 1 772  ? 186.310 98.934  108.928 1.00 15.26  ? 772  ILE   C C     1 
ATOM   4521 O O     . ILE   A 1 772  ? 186.769 98.985  110.068 1.00 19.36  ? 772  ILE   C O     1 
ATOM   4522 C CB    . ILE   A 1 772  ? 183.995 97.972  109.223 1.00 12.89  ? 772  ILE   C CB    1 
ATOM   4523 C CG1   . ILE   A 1 772  ? 183.013 96.938  108.645 1.00 16.39  ? 772  ILE   C CG1   1 
ATOM   4524 C CG2   . ILE   A 1 772  ? 183.459 99.396  109.053 1.00 9.99   ? 772  ILE   C CG2   1 
ATOM   4525 C CD1   . ILE   A 1 772  ? 181.701 96.840  109.389 1.00 16.77  ? 772  ILE   C CD1   1 
ATOM   4526 N N     . ARG   A 1 773  ? 186.618 99.820  107.980 1.00 13.39  ? 773  ARG   C N     1 
ATOM   4527 C CA    . ARG   A 1 773  ? 187.565 100.900 108.233 1.00 10.47  ? 773  ARG   C CA    1 
ATOM   4528 C C     . ARG   A 1 773  ? 186.877 102.242 108.431 1.00 9.31   ? 773  ARG   C C     1 
ATOM   4529 O O     . ARG   A 1 773  ? 187.387 103.109 109.143 1.00 15.28  ? 773  ARG   C O     1 
ATOM   4530 C CB    . ARG   A 1 773  ? 188.562 101.016 107.098 1.00 10.40  ? 773  ARG   C CB    1 
ATOM   4531 C CG    . ARG   A 1 773  ? 189.507 99.840  106.973 1.00 15.03  ? 773  ARG   C CG    1 
ATOM   4532 C CD    . ARG   A 1 773  ? 190.449 100.003 105.840 1.00 16.82  ? 773  ARG   C CD    1 
ATOM   4533 N NE    . ARG   A 1 773  ? 191.410 98.913  105.777 1.00 20.23  ? 773  ARG   C NE    1 
ATOM   4534 C CZ    . ARG   A 1 773  ? 191.176 97.706  105.219 1.00 26.07  ? 773  ARG   C CZ    1 
ATOM   4535 N NH1   . ARG   A 1 773  ? 190.007 97.436  104.677 1.00 23.78  ? 773  ARG   C NH1   1 
ATOM   4536 N NH2   . ARG   A 1 773  ? 192.126 96.790  105.221 1.00 27.19  ? 773  ARG   C NH2   1 
ATOM   4537 N N     . ARG   A 1 774  ? 185.724 102.423 107.808 1.00 7.71   ? 774  ARG   C N     1 
ATOM   4538 C CA    . ARG   A 1 774  ? 185.009 103.684 107.938 1.00 7.29   ? 774  ARG   C CA    1 
ATOM   4539 C C     . ARG   A 1 774  ? 183.583 103.442 108.397 1.00 6.61   ? 774  ARG   C C     1 
ATOM   4540 O O     . ARG   A 1 774  ? 182.846 102.677 107.772 1.00 12.28  ? 774  ARG   C O     1 
ATOM   4541 C CB    . ARG   A 1 774  ? 185.011 104.433 106.617 1.00 7.77   ? 774  ARG   C CB    1 
ATOM   4542 C CG    . ARG   A 1 774  ? 186.397 104.763 106.075 1.00 8.48   ? 774  ARG   C CG    1 
ATOM   4543 C CD    . ARG   A 1 774  ? 186.334 105.629 104.861 1.00 7.80   ? 774  ARG   C CD    1 
ATOM   4544 N NE    . ARG   A 1 774  ? 185.756 104.938 103.714 1.00 10.94  ? 774  ARG   C NE    1 
ATOM   4545 C CZ    . ARG   A 1 774  ? 186.431 104.151 102.854 1.00 13.96  ? 774  ARG   C CZ    1 
ATOM   4546 N NH1   . ARG   A 1 774  ? 187.724 103.941 103.001 1.00 11.84  ? 774  ARG   C NH1   1 
ATOM   4547 N NH2   . ARG   A 1 774  ? 185.773 103.593 101.856 1.00 13.11  ? 774  ARG   C NH2   1 
ATOM   4548 N N     . LEU   A 1 775  ? 183.205 104.069 109.505 1.00 3.19   ? 775  LEU   C N     1 
ATOM   4549 C CA    . LEU   A 1 775  ? 181.872 103.881 110.059 1.00 4.31   ? 775  LEU   C CA    1 
ATOM   4550 C C     . LEU   A 1 775  ? 181.161 105.214 110.242 1.00 0.49   ? 775  LEU   C C     1 
ATOM   4551 O O     . LEU   A 1 775  ? 181.644 106.094 110.959 1.00 19.12  ? 775  LEU   C O     1 
ATOM   4552 C CB    . LEU   A 1 775  ? 181.974 103.142 111.400 1.00 0.75   ? 775  LEU   C CB    1 
ATOM   4553 C CG    . LEU   A 1 775  ? 180.665 102.867 112.146 1.00 0.33   ? 775  LEU   C CG    1 
ATOM   4554 C CD1   . LEU   A 1 775  ? 179.794 101.906 111.346 1.00 7.59   ? 775  LEU   C CD1   1 
ATOM   4555 C CD2   . LEU   A 1 775  ? 180.992 102.280 113.498 1.00 8.34   ? 775  LEU   C CD2   1 
ATOM   4556 N N     . TRP   A 1 776  ? 180.017 105.363 109.589 1.00 9.66   ? 776  TRP   C N     1 
ATOM   4557 C CA    . TRP   A 1 776  ? 179.260 106.605 109.659 1.00 0.40   ? 776  TRP   C CA    1 
ATOM   4558 C C     . TRP   A 1 776  ? 178.008 106.435 110.510 1.00 9.35   ? 776  TRP   C C     1 
ATOM   4559 O O     . TRP   A 1 776  ? 177.123 105.645 110.175 1.00 8.28   ? 776  TRP   C O     1 
ATOM   4560 C CB    . TRP   A 1 776  ? 178.880 107.065 108.252 1.00 7.15   ? 776  TRP   C CB    1 
ATOM   4561 C CG    . TRP   A 1 776  ? 180.068 107.329 107.372 1.00 8.27   ? 776  TRP   C CG    1 
ATOM   4562 C CD1   . TRP   A 1 776  ? 180.688 106.431 106.570 1.00 9.54   ? 776  TRP   C CD1   1 
ATOM   4563 C CD2   . TRP   A 1 776  ? 180.784 108.568 107.203 1.00 10.60  ? 776  TRP   C CD2   1 
ATOM   4564 N NE1   . TRP   A 1 776  ? 181.737 107.023 105.922 1.00 8.86   ? 776  TRP   C NE1   1 
ATOM   4565 C CE2   . TRP   A 1 776  ? 181.810 108.324 106.295 1.00 9.84   ? 776  TRP   C CE2   1 
ATOM   4566 C CE3   . TRP   A 1 776  ? 180.632 109.844 107.727 1.00 14.76  ? 776  TRP   C CE3   1 
ATOM   4567 C CZ2   . TRP   A 1 776  ? 182.702 109.305 105.918 1.00 16.21  ? 776  TRP   C CZ2   1 
ATOM   4568 C CZ3   . TRP   A 1 776  ? 181.525 110.836 107.349 1.00 15.33  ? 776  TRP   C CZ3   1 
ATOM   4569 C CH2   . TRP   A 1 776  ? 182.534 110.572 106.465 1.00 15.98  ? 776  TRP   C CH2   1 
ATOM   4570 N N     . LEU   A 1 777  ? 177.934 107.173 111.617 1.00 9.12   ? 777  LEU   C N     1 
ATOM   4571 C CA    . LEU   A 1 777  ? 176.811 107.081 112.543 1.00 10.95  ? 777  LEU   C CA    1 
ATOM   4572 C C     . LEU   A 1 777  ? 176.232 108.460 112.811 1.00 11.15  ? 777  LEU   C C     1 
ATOM   4573 O O     . LEU   A 1 777  ? 176.368 108.977 113.919 1.00 6.80   ? 777  LEU   C O     1 
ATOM   4574 C CB    . LEU   A 1 777  ? 177.277 106.499 113.882 1.00 5.72   ? 777  LEU   C CB    1 
ATOM   4575 C CG    . LEU   A 1 777  ? 177.922 105.132 113.844 1.00 2.52   ? 777  LEU   C CG    1 
ATOM   4576 C CD1   . LEU   A 1 777  ? 178.562 104.864 115.184 1.00 1.20   ? 777  LEU   C CD1   1 
ATOM   4577 C CD2   . LEU   A 1 777  ? 176.888 104.072 113.525 1.00 7.14   ? 777  LEU   C CD2   1 
ATOM   4578 N N     . GLY   A 1 778  ? 175.614 109.061 111.800 1.00 7.59   ? 778  GLY   C N     1 
ATOM   4579 C CA    . GLY   A 1 778  ? 175.149 110.440 111.898 1.00 6.90   ? 778  GLY   C CA    1 
ATOM   4580 C C     . GLY   A 1 778  ? 173.935 110.574 112.805 1.00 7.53   ? 778  GLY   C C     1 
ATOM   4581 O O     . GLY   A 1 778  ? 173.966 110.178 113.967 1.00 9.03   ? 778  GLY   C O     1 
ATOM   4582 N N     . ARG   A 1 779  ? 172.856 111.145 112.288 1.00 8.25   ? 779  ARG   C N     1 
ATOM   4583 C CA    . ARG   A 1 779  ? 171.699 111.422 113.130 1.00 8.27   ? 779  ARG   C CA    1 
ATOM   4584 C C     . ARG   A 1 779  ? 170.933 110.151 113.488 1.00 12.12  ? 779  ARG   C C     1 
ATOM   4585 O O     . ARG   A 1 779  ? 169.832 109.911 112.995 1.00 17.85  ? 779  ARG   C O     1 
ATOM   4586 C CB    . ARG   A 1 779  ? 170.772 112.407 112.434 1.00 9.94   ? 779  ARG   C CB    1 
ATOM   4587 C CG    . ARG   A 1 779  ? 169.602 112.915 113.271 1.00 14.52  ? 779  ARG   C CG    1 
ATOM   4588 C CD    . ARG   A 1 779  ? 168.774 113.887 112.511 1.00 16.00  ? 779  ARG   C CD    1 
ATOM   4589 N NE    . ARG   A 1 779  ? 169.519 115.103 112.201 1.00 15.68  ? 779  ARG   C NE    1 
ATOM   4590 C CZ    . ARG   A 1 779  ? 169.659 116.162 113.031 1.00 20.85  ? 779  ARG   C CZ    1 
ATOM   4591 N NH1   . ARG   A 1 779  ? 169.096 116.154 114.222 1.00 17.08  ? 779  ARG   C NH1   1 
ATOM   4592 N NH2   . ARG   A 1 779  ? 170.366 117.211 112.648 1.00 20.47  ? 779  ARG   C NH2   1 
ATOM   4593 N N     . CYS   A 1 780  ? 171.529 109.342 114.361 1.00 11.53  ? 780  CYS   C N     1 
ATOM   4594 C CA    . CYS   A 1 780  ? 170.940 108.084 114.805 1.00 10.65  ? 780  CYS   C CA    1 
ATOM   4595 C C     . CYS   A 1 780  ? 170.220 108.228 116.139 1.00 12.33  ? 780  CYS   C C     1 
ATOM   4596 O O     . CYS   A 1 780  ? 169.523 107.316 116.580 1.00 17.79  ? 780  CYS   C O     1 
ATOM   4597 C CB    . CYS   A 1 780  ? 172.015 107.013 114.937 1.00 10.51  ? 780  CYS   C CB    1 
ATOM   4598 S SG    . CYS   A 1 780  ? 172.786 106.537 113.388 1.00 12.14  ? 780  CYS   C SG    1 
ATOM   4599 N N     . GLY   A 1 781  ? 170.386 109.377 116.779 1.00 12.97  ? 781  GLY   C N     1 
ATOM   4600 C CA    . GLY   A 1 781  ? 169.750 109.630 118.064 1.00 12.45  ? 781  GLY   C CA    1 
ATOM   4601 C C     . GLY   A 1 781  ? 170.432 108.893 119.212 1.00 12.84  ? 781  GLY   C C     1 
ATOM   4602 O O     . GLY   A 1 781  ? 169.775 108.504 120.177 1.00 16.64  ? 781  GLY   C O     1 
ATOM   4603 N N     . LEU   A 1 782  ? 171.743 108.697 119.110 1.00 14.67  ? 782  LEU   C N     1 
ATOM   4604 C CA    . LEU   A 1 782  ? 172.479 107.985 120.151 1.00 15.31  ? 782  LEU   C CA    1 
ATOM   4605 C C     . LEU   A 1 782  ? 172.644 108.852 121.391 1.00 14.75  ? 782  LEU   C C     1 
ATOM   4606 O O     . LEU   A 1 782  ? 172.762 110.076 121.289 1.00 17.74  ? 782  LEU   C O     1 
ATOM   4607 C CB    . LEU   A 1 782  ? 173.872 107.587 119.654 1.00 14.40  ? 782  LEU   C CB    1 
ATOM   4608 C CG    . LEU   A 1 782  ? 173.942 106.655 118.447 1.00 12.87  ? 782  LEU   C CG    1 
ATOM   4609 C CD1   . LEU   A 1 782  ? 175.400 106.481 118.034 1.00 11.41  ? 782  LEU   C CD1   1 
ATOM   4610 C CD2   . LEU   A 1 782  ? 173.326 105.323 118.797 1.00 18.06  ? 782  LEU   C CD2   1 
ATOM   4611 N N     . SER   A 1 783  ? 172.676 108.220 122.562 1.00 13.75  ? 783  SER   C N     1 
ATOM   4612 C CA    . SER   A 1 783  ? 172.905 108.953 123.804 1.00 13.13  ? 783  SER   C CA    1 
ATOM   4613 C C     . SER   A 1 783  ? 174.272 108.652 124.390 1.00 14.96  ? 783  SER   C C     1 
ATOM   4614 O O     . SER   A 1 783  ? 175.056 107.901 123.811 1.00 17.76  ? 783  SER   C O     1 
ATOM   4615 C CB    . SER   A 1 783  ? 171.851 108.627 124.831 1.00 20.11  ? 783  SER   C CB    1 
ATOM   4616 O OG    . SER   A 1 783  ? 172.045 109.392 125.987 1.00 22.81  ? 783  SER   C OG    1 
ATOM   4617 N N     . HIS   A 1 784  ? 174.560 109.229 125.552 1.00 13.72  ? 784  HIS   C N     1 
ATOM   4618 C CA    . HIS   A 1 784  ? 175.878 109.083 126.160 1.00 11.90  ? 784  HIS   C CA    1 
ATOM   4619 C C     . HIS   A 1 784  ? 176.185 107.651 126.560 1.00 14.76  ? 784  HIS   C C     1 
ATOM   4620 O O     . HIS   A 1 784  ? 177.347 107.255 126.626 1.00 17.72  ? 784  HIS   C O     1 
ATOM   4621 C CB    . HIS   A 1 784  ? 176.011 109.980 127.387 1.00 12.71  ? 784  HIS   C CB    1 
ATOM   4622 C CG    . HIS   A 1 784  ? 175.019 109.680 128.446 1.00 14.41  ? 784  HIS   C CG    1 
ATOM   4623 N ND1   . HIS   A 1 784  ? 173.737 110.181 128.422 1.00 17.48  ? 784  HIS   C ND1   1 
ATOM   4624 C CD2   . HIS   A 1 784  ? 175.103 108.918 129.558 1.00 17.20  ? 784  HIS   C CD2   1 
ATOM   4625 C CE1   . HIS   A 1 784  ? 173.077 109.741 129.478 1.00 20.97  ? 784  HIS   C CE1   1 
ATOM   4626 N NE2   . HIS   A 1 784  ? 173.885 108.974 130.183 1.00 17.65  ? 784  HIS   C NE2   1 
ATOM   4627 N N     . GLU   A 1 785  ? 175.156 106.853 126.795 1.00 18.29  ? 785  GLU   C N     1 
ATOM   4628 C CA    . GLU   A 1 785  ? 175.375 105.473 127.207 1.00 18.53  ? 785  GLU   C CA    1 
ATOM   4629 C C     . GLU   A 1 785  ? 176.074 104.659 126.127 1.00 18.82  ? 785  GLU   C C     1 
ATOM   4630 O O     . GLU   A 1 785  ? 176.842 103.747 126.434 1.00 21.03  ? 785  GLU   C O     1 
ATOM   4631 C CB    . GLU   A 1 785  ? 174.056 104.803 127.596 1.00 17.05  ? 785  GLU   C CB    1 
ATOM   4632 C CG    . GLU   A 1 785  ? 173.495 105.249 128.946 1.00 26.20  ? 785  GLU   C CG    1 
ATOM   4633 C CD    . GLU   A 1 785  ? 174.373 104.840 130.115 1.00 30.07  ? 785  GLU   C CD    1 
ATOM   4634 O OE1   . GLU   A 1 785  ? 174.794 103.710 130.151 1.00 23.22  ? 785  GLU   C OE1   1 
ATOM   4635 O OE2   . GLU   A 1 785  ? 174.620 105.661 130.966 1.00 28.51  ? 785  GLU   C OE2   1 
ATOM   4636 N N     . CYS   A 1 786  ? 175.833 104.982 124.858 1.00 18.49  ? 786  CYS   C N     1 
ATOM   4637 C CA    . CYS   A 1 786  ? 176.423 104.206 123.777 1.00 16.17  ? 786  CYS   C CA    1 
ATOM   4638 C C     . CYS   A 1 786  ? 177.928 104.429 123.682 1.00 18.67  ? 786  CYS   C C     1 
ATOM   4639 O O     . CYS   A 1 786  ? 178.627 103.658 123.028 1.00 20.44  ? 786  CYS   C O     1 
ATOM   4640 C CB    . CYS   A 1 786  ? 175.832 104.586 122.434 1.00 15.03  ? 786  CYS   C CB    1 
ATOM   4641 S SG    . CYS   A 1 786  ? 176.484 106.122 121.802 1.00 22.10  ? 786  CYS   C SG    1 
ATOM   4642 N N     . CYS   A 1 787  ? 178.427 105.500 124.310 1.00 16.62  ? 787  CYS   C N     1 
ATOM   4643 C CA    . CYS   A 1 787  ? 179.843 105.821 124.226 1.00 11.63  ? 787  CYS   C CA    1 
ATOM   4644 C C     . CYS   A 1 787  ? 180.666 104.817 124.993 1.00 12.73  ? 787  CYS   C C     1 
ATOM   4645 O O     . CYS   A 1 787  ? 181.855 104.645 124.729 1.00 15.25  ? 787  CYS   C O     1 
ATOM   4646 C CB    . CYS   A 1 787  ? 180.126 107.213 124.763 1.00 11.69  ? 787  CYS   C CB    1 
ATOM   4647 S SG    . CYS   A 1 787  ? 179.493 108.512 123.720 1.00 14.98  ? 787  CYS   C SG    1 
ATOM   4648 N N     . PHE   A 1 788  ? 180.041 104.138 125.940 1.00 13.49  ? 788  PHE   C N     1 
ATOM   4649 C CA    . PHE   A 1 788  ? 180.738 103.110 126.680 1.00 13.87  ? 788  PHE   C CA    1 
ATOM   4650 C C     . PHE   A 1 788  ? 181.127 101.993 125.725 1.00 17.91  ? 788  PHE   C C     1 
ATOM   4651 O O     . PHE   A 1 788  ? 182.246 101.482 125.762 1.00 18.51  ? 788  PHE   C O     1 
ATOM   4652 C CB    . PHE   A 1 788  ? 179.868 102.574 127.808 1.00 13.02  ? 788  PHE   C CB    1 
ATOM   4653 C CG    . PHE   A 1 788  ? 180.532 101.515 128.592 1.00 10.22  ? 788  PHE   C CG    1 
ATOM   4654 C CD1   . PHE   A 1 788  ? 181.517 101.829 129.502 1.00 10.02  ? 788  PHE   C CD1   1 
ATOM   4655 C CD2   . PHE   A 1 788  ? 180.183 100.195 128.417 1.00 14.90  ? 788  PHE   C CD2   1 
ATOM   4656 C CE1   . PHE   A 1 788  ? 182.144 100.841 130.220 1.00 12.82  ? 788  PHE   C CE1   1 
ATOM   4657 C CE2   . PHE   A 1 788  ? 180.805 99.205  129.134 1.00 15.48  ? 788  PHE   C CE2   1 
ATOM   4658 C CZ    . PHE   A 1 788  ? 181.788 99.527  130.036 1.00 13.62  ? 788  PHE   C CZ    1 
ATOM   4659 N N     . ASP   A 1 789  ? 180.189 101.623 124.861 1.00 17.85  ? 789  ASP   C N     1 
ATOM   4660 C CA    . ASP   A 1 789  ? 180.391 100.531 123.929 1.00 15.55  ? 789  ASP   C CA    1 
ATOM   4661 C C     . ASP   A 1 789  ? 181.292 100.955 122.772 1.00 18.77  ? 789  ASP   C C     1 
ATOM   4662 O O     . ASP   A 1 789  ? 182.090 100.157 122.277 1.00 20.82  ? 789  ASP   C O     1 
ATOM   4663 C CB    . ASP   A 1 789  ? 179.043 100.060 123.405 1.00 14.72  ? 789  ASP   C CB    1 
ATOM   4664 C CG    . ASP   A 1 789  ? 178.170 99.476  124.487 1.00 21.87  ? 789  ASP   C CG    1 
ATOM   4665 O OD1   . ASP   A 1 789  ? 178.683 98.818  125.360 1.00 21.11  ? 789  ASP   C OD1   1 
ATOM   4666 O OD2   . ASP   A 1 789  ? 176.987 99.706  124.443 1.00 26.17  ? 789  ASP   C OD2   1 
ATOM   4667 N N     . ILE   A 1 790  ? 181.195 102.218 122.361 1.00 17.59  ? 790  ILE   C N     1 
ATOM   4668 C CA    . ILE   A 1 790  ? 182.063 102.726 121.305 1.00 13.55  ? 790  ILE   C CA    1 
ATOM   4669 C C     . ILE   A 1 790  ? 183.505 102.715 121.789 1.00 15.01  ? 790  ILE   C C     1 
ATOM   4670 O O     . ILE   A 1 790  ? 184.414 102.361 121.038 1.00 18.89  ? 790  ILE   C O     1 
ATOM   4671 C CB    . ILE   A 1 790  ? 181.659 104.138 120.845 1.00 10.73  ? 790  ILE   C CB    1 
ATOM   4672 C CG1   . ILE   A 1 790  ? 180.301 104.078 120.133 1.00 12.27  ? 790  ILE   C CG1   1 
ATOM   4673 C CG2   . ILE   A 1 790  ? 182.730 104.710 119.909 1.00 10.44  ? 790  ILE   C CG2   1 
ATOM   4674 C CD1   . ILE   A 1 790  ? 179.654 105.431 119.916 1.00 10.93  ? 790  ILE   C CD1   1 
ATOM   4675 N N     . SER   A 1 791  ? 183.714 103.107 123.045 1.00 14.31  ? 791  SER   C N     1 
ATOM   4676 C CA    . SER   A 1 791  ? 185.043 103.099 123.638 1.00 13.34  ? 791  SER   C CA    1 
ATOM   4677 C C     . SER   A 1 791  ? 185.646 101.702 123.602 1.00 18.41  ? 791  SER   C C     1 
ATOM   4678 O O     . SER   A 1 791  ? 186.814 101.530 123.245 1.00 19.84  ? 791  SER   C O     1 
ATOM   4679 C CB    . SER   A 1 791  ? 184.975 103.581 125.068 1.00 13.88  ? 791  SER   C CB    1 
ATOM   4680 O OG    . SER   A 1 791  ? 186.238 103.558 125.665 1.00 18.27  ? 791  SER   C OG    1 
ATOM   4681 N N     . LEU   A 1 792  ? 184.839 100.695 123.941 1.00 20.33  ? 792  LEU   C N     1 
ATOM   4682 C CA    . LEU   A 1 792  ? 185.309 99.315  123.929 1.00 20.11  ? 792  LEU   C CA    1 
ATOM   4683 C C     . LEU   A 1 792  ? 185.744 98.888  122.533 1.00 21.59  ? 792  LEU   C C     1 
ATOM   4684 O O     . LEU   A 1 792  ? 186.723 98.157  122.384 1.00 23.92  ? 792  LEU   C O     1 
ATOM   4685 C CB    . LEU   A 1 792  ? 184.209 98.366  124.422 1.00 16.56  ? 792  LEU   C CB    1 
ATOM   4686 C CG    . LEU   A 1 792  ? 183.828 98.461  125.907 1.00 15.64  ? 792  LEU   C CG    1 
ATOM   4687 C CD1   . LEU   A 1 792  ? 182.591 97.619  126.149 1.00 18.19  ? 792  LEU   C CD1   1 
ATOM   4688 C CD2   . LEU   A 1 792  ? 184.979 97.972  126.774 1.00 18.47  ? 792  LEU   C CD2   1 
ATOM   4689 N N     . VAL   A 1 793  ? 185.030 99.352  121.509 1.00 19.10  ? 793  VAL   C N     1 
ATOM   4690 C CA    . VAL   A 1 793  ? 185.402 99.023  120.138 1.00 17.07  ? 793  VAL   C CA    1 
ATOM   4691 C C     . VAL   A 1 793  ? 186.720 99.685  119.756 1.00 21.12  ? 793  VAL   C C     1 
ATOM   4692 O O     . VAL   A 1 793  ? 187.597 99.044  119.187 1.00 23.41  ? 793  VAL   C O     1 
ATOM   4693 C CB    . VAL   A 1 793  ? 184.311 99.461  119.142 1.00 15.91  ? 793  VAL   C CB    1 
ATOM   4694 C CG1   . VAL   A 1 793  ? 184.799 99.278  117.702 1.00 16.62  ? 793  VAL   C CG1   1 
ATOM   4695 C CG2   . VAL   A 1 793  ? 183.064 98.641  119.370 1.00 23.61  ? 793  VAL   C CG2   1 
ATOM   4696 N N     . LEU   A 1 794  ? 186.870 100.967 120.078 1.00 21.69  ? 794  LEU   C N     1 
ATOM   4697 C CA    . LEU   A 1 794  ? 188.081 101.700 119.713 1.00 18.55  ? 794  LEU   C CA    1 
ATOM   4698 C C     . LEU   A 1 794  ? 189.331 101.095 120.342 1.00 20.67  ? 794  LEU   C C     1 
ATOM   4699 O O     . LEU   A 1 794  ? 190.397 101.077 119.728 1.00 24.56  ? 794  LEU   C O     1 
ATOM   4700 C CB    . LEU   A 1 794  ? 187.964 103.168 120.148 1.00 14.54  ? 794  LEU   C CB    1 
ATOM   4701 C CG    . LEU   A 1 794  ? 186.969 104.044 119.369 1.00 11.23  ? 794  LEU   C CG    1 
ATOM   4702 C CD1   . LEU   A 1 794  ? 186.800 105.370 120.095 1.00 12.20  ? 794  LEU   C CD1   1 
ATOM   4703 C CD2   . LEU   A 1 794  ? 187.490 104.282 117.964 1.00 11.18  ? 794  LEU   C CD2   1 
ATOM   4704 N N     . SER   A 1 795  ? 189.197 100.577 121.557 1.00 20.50  ? 795  SER   C N     1 
ATOM   4705 C CA    . SER   A 1 795  ? 190.332 100.013 122.279 1.00 23.61  ? 795  SER   C CA    1 
ATOM   4706 C C     . SER   A 1 795  ? 190.768 98.633  121.775 1.00 25.61  ? 795  SER   C C     1 
ATOM   4707 O O     . SER   A 1 795  ? 191.807 98.126  122.202 1.00 28.09  ? 795  SER   C O     1 
ATOM   4708 C CB    . SER   A 1 795  ? 190.011 99.918  123.758 1.00 25.32  ? 795  SER   C CB    1 
ATOM   4709 O OG    . SER   A 1 795  ? 189.840 101.190 124.324 1.00 25.11  ? 795  SER   C OG    1 
ATOM   4710 N N     . SER   A 1 796  ? 189.979 97.999  120.904 1.00 23.51  ? 796  SER   C N     1 
ATOM   4711 C CA    . SER   A 1 796  ? 190.349 96.667  120.422 1.00 23.91  ? 796  SER   C CA    1 
ATOM   4712 C C     . SER   A 1 796  ? 190.335 96.567  118.898 1.00 26.06  ? 796  SER   C C     1 
ATOM   4713 O O     . SER   A 1 796  ? 191.026 95.727  118.316 1.00 27.20  ? 796  SER   C O     1 
ATOM   4714 C CB    . SER   A 1 796  ? 189.423 95.619  121.005 1.00 24.11  ? 796  SER   C CB    1 
ATOM   4715 O OG    . SER   A 1 796  ? 188.113 95.778  120.536 1.00 24.79  ? 796  SER   C OG    1 
ATOM   4716 N N     . ASN   A 1 797  ? 189.560 97.427  118.248 1.00 25.08  ? 797  ASN   C N     1 
ATOM   4717 C CA    . ASN   A 1 797  ? 189.434 97.414  116.800 1.00 22.54  ? 797  ASN   C CA    1 
ATOM   4718 C C     . ASN   A 1 797  ? 190.542 98.244  116.183 1.00 22.03  ? 797  ASN   C C     1 
ATOM   4719 O O     . ASN   A 1 797  ? 190.498 99.472  116.215 1.00 21.27  ? 797  ASN   C O     1 
ATOM   4720 C CB    . ASN   A 1 797  ? 188.074 97.930  116.370 1.00 19.55  ? 797  ASN   C CB    1 
ATOM   4721 C CG    . ASN   A 1 797  ? 187.855 97.860  114.886 1.00 22.28  ? 797  ASN   C CG    1 
ATOM   4722 O OD1   . ASN   A 1 797  ? 188.806 97.870  114.087 1.00 24.28  ? 797  ASN   C OD1   1 
ATOM   4723 N ND2   . ASN   A 1 797  ? 186.608 97.791  114.492 1.00 22.48  ? 797  ASN   C ND2   1 
ATOM   4724 N N     . GLN   A 1 798  ? 191.537 97.566  115.628 1.00 24.13  ? 798  GLN   C N     1 
ATOM   4725 C CA    . GLN   A 1 798  ? 192.718 98.227  115.089 1.00 25.36  ? 798  GLN   C CA    1 
ATOM   4726 C C     . GLN   A 1 798  ? 192.556 98.579  113.614 1.00 28.21  ? 798  GLN   C C     1 
ATOM   4727 O O     . GLN   A 1 798  ? 193.489 99.081  112.985 1.00 26.80  ? 798  GLN   C O     1 
ATOM   4728 C CB    . GLN   A 1 798  ? 193.950 97.338  115.283 1.00 28.15  ? 798  GLN   C CB    1 
ATOM   4729 C CG    . GLN   A 1 798  ? 194.312 97.107  116.739 1.00 32.15  ? 798  GLN   C CG    1 
ATOM   4730 C CD    . GLN   A 1 798  ? 195.531 96.221  116.914 1.00 41.95  ? 798  GLN   C CD    1 
ATOM   4731 O OE1   . GLN   A 1 798  ? 196.591 96.477  116.336 1.00 40.13  ? 798  GLN   C OE1   1 
ATOM   4732 N NE2   . GLN   A 1 798  ? 195.388 95.170  117.714 1.00 38.81  ? 798  GLN   C NE2   1 
ATOM   4733 N N     . LYS   A 1 799  ? 191.378 98.300  113.058 1.00 24.55  ? 799  LYS   C N     1 
ATOM   4734 C CA    . LYS   A 1 799  ? 191.131 98.559  111.645 1.00 18.52  ? 799  LYS   C CA    1 
ATOM   4735 C C     . LYS   A 1 799  ? 190.397 99.877  111.435 1.00 16.75  ? 799  LYS   C C     1 
ATOM   4736 O O     . LYS   A 1 799  ? 190.660 100.586 110.468 1.00 18.44  ? 799  LYS   C O     1 
ATOM   4737 C CB    . LYS   A 1 799  ? 190.311 97.425  111.025 1.00 20.60  ? 799  LYS   C CB    1 
ATOM   4738 C CG    . LYS   A 1 799  ? 190.947 96.038  111.115 1.00 25.28  ? 799  LYS   C CG    1 
ATOM   4739 C CD    . LYS   A 1 799  ? 192.257 95.952  110.343 1.00 28.62  ? 799  LYS   C CD    1 
ATOM   4740 C CE    . LYS   A 1 799  ? 192.793 94.527  110.339 1.00 32.95  ? 799  LYS   C CE    1 
ATOM   4741 N NZ    . LYS   A 1 799  ? 194.108 94.429  109.650 1.00 36.86  ? 799  LYS   C NZ    1 
ATOM   4742 N N     . LEU   A 1 800  ? 189.490 100.213 112.347 1.00 16.18  ? 800  LEU   C N     1 
ATOM   4743 C CA    . LEU   A 1 800  ? 188.676 101.417 112.197 1.00 12.01  ? 800  LEU   C CA    1 
ATOM   4744 C C     . LEU   A 1 800  ? 189.544 102.674 112.136 1.00 11.47  ? 800  LEU   C C     1 
ATOM   4745 O O     . LEU   A 1 800  ? 190.383 102.906 113.005 1.00 15.33  ? 800  LEU   C O     1 
ATOM   4746 C CB    . LEU   A 1 800  ? 187.678 101.515 113.365 1.00 11.11  ? 800  LEU   C CB    1 
ATOM   4747 C CG    . LEU   A 1 800  ? 186.650 102.671 113.321 1.00 7.09   ? 800  LEU   C CG    1 
ATOM   4748 C CD1   . LEU   A 1 800  ? 185.683 102.472 112.160 1.00 7.87   ? 800  LEU   C CD1   1 
ATOM   4749 C CD2   . LEU   A 1 800  ? 185.889 102.705 114.635 1.00 6.94   ? 800  LEU   C CD2   1 
ATOM   4750 N N     . VAL   A 1 801  ? 189.333 103.480 111.093 1.00 9.53   ? 801  VAL   C N     1 
ATOM   4751 C CA    . VAL   A 1 801  ? 190.092 104.705 110.860 1.00 8.13   ? 801  VAL   C CA    1 
ATOM   4752 C C     . VAL   A 1 801  ? 189.242 105.964 110.985 1.00 2.59   ? 801  VAL   C C     1 
ATOM   4753 O O     . VAL   A 1 801  ? 189.700 106.976 111.518 1.00 0.00   ? 801  VAL   C O     1 
ATOM   4754 C CB    . VAL   A 1 801  ? 190.741 104.683 109.468 1.00 7.81   ? 801  VAL   C CB    1 
ATOM   4755 C CG1   . VAL   A 1 801  ? 191.442 105.992 109.202 1.00 8.39   ? 801  VAL   C CG1   1 
ATOM   4756 C CG2   . VAL   A 1 801  ? 191.728 103.553 109.394 1.00 9.01   ? 801  VAL   C CG2   1 
ATOM   4757 N N     . GLU   A 1 802  ? 188.035 105.931 110.437 1.00 0.03   ? 802  GLU   C N     1 
ATOM   4758 C CA    . GLU   A 1 802  ? 187.195 107.125 110.421 1.00 0.14   ? 802  GLU   C CA    1 
ATOM   4759 C C     . GLU   A 1 802  ? 185.879 106.881 111.146 1.00 0.01   ? 802  GLU   C C     1 
ATOM   4760 O O     . GLU   A 1 802  ? 185.185 105.901 110.869 1.00 0.00   ? 802  GLU   C O     1 
ATOM   4761 C CB    . GLU   A 1 802  ? 186.914 107.548 108.979 1.00 8.54   ? 802  GLU   C CB    1 
ATOM   4762 C CG    . GLU   A 1 802  ? 188.164 107.784 108.135 1.00 6.83   ? 802  GLU   C CG    1 
ATOM   4763 C CD    . GLU   A 1 802  ? 187.854 108.254 106.745 1.00 9.16   ? 802  GLU   C CD    1 
ATOM   4764 O OE1   . GLU   A 1 802  ? 186.697 108.306 106.407 1.00 11.47  ? 802  GLU   C OE1   1 
ATOM   4765 O OE2   . GLU   A 1 802  ? 188.768 108.573 106.021 1.00 10.05  ? 802  GLU   C OE2   1 
ATOM   4766 N N     . LEU   A 1 803  ? 185.529 107.776 112.069 1.00 0.02   ? 803  LEU   C N     1 
ATOM   4767 C CA    . LEU   A 1 803  ? 184.292 107.625 112.831 1.00 0.02   ? 803  LEU   C CA    1 
ATOM   4768 C C     . LEU   A 1 803  ? 183.496 108.920 112.892 1.00 0.00   ? 803  LEU   C C     1 
ATOM   4769 O O     . LEU   A 1 803  ? 183.980 109.932 113.403 1.00 0.00   ? 803  LEU   C O     1 
ATOM   4770 C CB    . LEU   A 1 803  ? 184.619 107.151 114.253 1.00 0.00   ? 803  LEU   C CB    1 
ATOM   4771 C CG    . LEU   A 1 803  ? 183.445 106.981 115.221 1.00 0.00   ? 803  LEU   C CG    1 
ATOM   4772 C CD1   . LEU   A 1 803  ? 182.531 105.866 114.737 1.00 0.00   ? 803  LEU   C CD1   1 
ATOM   4773 C CD2   . LEU   A 1 803  ? 183.991 106.670 116.606 1.00 0.01   ? 803  LEU   C CD2   1 
ATOM   4774 N N     . ASP   A 1 804  ? 182.266 108.883 112.389 1.00 0.04   ? 804  ASP   C N     1 
ATOM   4775 C CA    . ASP   A 1 804  ? 181.418 110.074 112.389 1.00 0.00   ? 804  ASP   C CA    1 
ATOM   4776 C C     . ASP   A 1 804  ? 180.267 109.984 113.381 1.00 0.01   ? 804  ASP   C C     1 
ATOM   4777 O O     . ASP   A 1 804  ? 179.355 109.179 113.199 1.00 0.00   ? 804  ASP   C O     1 
ATOM   4778 C CB    . ASP   A 1 804  ? 180.849 110.341 111.002 1.00 0.05   ? 804  ASP   C CB    1 
ATOM   4779 C CG    . ASP   A 1 804  ? 180.053 111.647 110.939 1.00 0.08   ? 804  ASP   C CG    1 
ATOM   4780 O OD1   . ASP   A 1 804  ? 179.895 112.266 111.973 1.00 1.10   ? 804  ASP   C OD1   1 
ATOM   4781 O OD2   . ASP   A 1 804  ? 179.602 112.007 109.875 1.00 0.13   ? 804  ASP   C OD2   1 
ATOM   4782 N N     . LEU   A 1 805  ? 180.327 110.787 114.446 1.00 0.10   ? 805  LEU   C N     1 
ATOM   4783 C CA    . LEU   A 1 805  ? 179.309 110.776 115.496 1.00 0.03   ? 805  LEU   C CA    1 
ATOM   4784 C C     . LEU   A 1 805  ? 178.454 112.046 115.489 1.00 0.02   ? 805  LEU   C C     1 
ATOM   4785 O O     . LEU   A 1 805  ? 177.812 112.380 116.490 1.00 0.29   ? 805  LEU   C O     1 
ATOM   4786 C CB    . LEU   A 1 805  ? 179.979 110.615 116.865 1.00 0.16   ? 805  LEU   C CB    1 
ATOM   4787 C CG    . LEU   A 1 805  ? 180.804 109.337 117.056 1.00 0.01   ? 805  LEU   C CG    1 
ATOM   4788 C CD1   . LEU   A 1 805  ? 181.520 109.393 118.387 1.00 0.01   ? 805  LEU   C CD1   1 
ATOM   4789 C CD2   . LEU   A 1 805  ? 179.897 108.121 116.991 1.00 0.02   ? 805  LEU   C CD2   1 
ATOM   4790 N N     . SER   A 1 806  ? 178.452 112.755 114.368 1.00 0.02   ? 806  SER   C N     1 
ATOM   4791 C CA    . SER   A 1 806  ? 177.741 114.023 114.265 1.00 0.00   ? 806  SER   C CA    1 
ATOM   4792 C C     . SER   A 1 806  ? 176.247 113.883 114.508 1.00 0.05   ? 806  SER   C C     1 
ATOM   4793 O O     . SER   A 1 806  ? 175.640 112.873 114.164 1.00 0.00   ? 806  SER   C O     1 
ATOM   4794 C CB    . SER   A 1 806  ? 177.934 114.624 112.889 1.00 0.07   ? 806  SER   C CB    1 
ATOM   4795 O OG    . SER   A 1 806  ? 179.285 114.853 112.622 1.00 7.91   ? 806  SER   C OG    1 
ATOM   4796 N N     . ASP   A 1 807  ? 175.661 114.926 115.082 1.00 0.19   ? 807  ASP   C N     1 
ATOM   4797 C CA    . ASP   A 1 807  ? 174.218 115.058 115.292 1.00 0.29   ? 807  ASP   C CA    1 
ATOM   4798 C C     . ASP   A 1 807  ? 173.607 114.090 116.308 1.00 8.60   ? 807  ASP   C C     1 
ATOM   4799 O O     . ASP   A 1 807  ? 172.386 114.048 116.465 1.00 11.55  ? 807  ASP   C O     1 
ATOM   4800 C CB    . ASP   A 1 807  ? 173.477 114.923 113.960 1.00 7.62   ? 807  ASP   C CB    1 
ATOM   4801 C CG    . ASP   A 1 807  ? 173.814 116.041 112.991 1.00 9.02   ? 807  ASP   C CG    1 
ATOM   4802 O OD1   . ASP   A 1 807  ? 173.798 117.179 113.396 1.00 10.81  ? 807  ASP   C OD1   1 
ATOM   4803 O OD2   . ASP   A 1 807  ? 174.083 115.749 111.852 1.00 11.90  ? 807  ASP   C OD2   1 
ATOM   4804 N N     . ASN   A 1 808  ? 174.437 113.364 117.047 1.00 9.09   ? 808  ASN   C N     1 
ATOM   4805 C CA    . ASN   A 1 808  ? 173.934 112.544 118.144 1.00 10.07  ? 808  ASN   C CA    1 
ATOM   4806 C C     . ASN   A 1 808  ? 173.819 113.404 119.396 1.00 12.45  ? 808  ASN   C C     1 
ATOM   4807 O O     . ASN   A 1 808  ? 174.134 114.591 119.363 1.00 15.59  ? 808  ASN   C O     1 
ATOM   4808 C CB    . ASN   A 1 808  ? 174.831 111.353 118.379 1.00 9.96   ? 808  ASN   C CB    1 
ATOM   4809 C CG    . ASN   A 1 808  ? 174.753 110.357 117.285 1.00 9.20   ? 808  ASN   C CG    1 
ATOM   4810 O OD1   . ASN   A 1 808  ? 173.737 109.666 117.104 1.00 13.05  ? 808  ASN   C OD1   1 
ATOM   4811 N ND2   . ASN   A 1 808  ? 175.816 110.269 116.540 1.00 7.64   ? 808  ASN   C ND2   1 
ATOM   4812 N N     . ALA   A 1 809  ? 173.361 112.825 120.499 1.00 13.09  ? 809  ALA   C N     1 
ATOM   4813 C CA    . ALA   A 1 809  ? 173.212 113.581 121.739 1.00 11.27  ? 809  ALA   C CA    1 
ATOM   4814 C C     . ALA   A 1 809  ? 174.278 113.169 122.740 1.00 12.89  ? 809  ALA   C C     1 
ATOM   4815 O O     . ALA   A 1 809  ? 174.009 112.991 123.929 1.00 16.10  ? 809  ALA   C O     1 
ATOM   4816 C CB    . ALA   A 1 809  ? 171.832 113.370 122.327 1.00 15.19  ? 809  ALA   C CB    1 
ATOM   4817 N N     . LEU   A 1 810  ? 175.495 113.011 122.253 1.00 13.73  ? 810  LEU   C N     1 
ATOM   4818 C CA    . LEU   A 1 810  ? 176.591 112.560 123.091 1.00 12.04  ? 810  LEU   C CA    1 
ATOM   4819 C C     . LEU   A 1 810  ? 177.157 113.744 123.839 1.00 11.75  ? 810  LEU   C C     1 
ATOM   4820 O O     . LEU   A 1 810  ? 178.126 114.355 123.396 1.00 16.01  ? 810  LEU   C O     1 
ATOM   4821 C CB    . LEU   A 1 810  ? 177.694 111.936 122.233 1.00 11.36  ? 810  LEU   C CB    1 
ATOM   4822 C CG    . LEU   A 1 810  ? 177.238 110.869 121.243 1.00 13.30  ? 810  LEU   C CG    1 
ATOM   4823 C CD1   . LEU   A 1 810  ? 178.442 110.300 120.534 1.00 13.84  ? 810  LEU   C CD1   1 
ATOM   4824 C CD2   . LEU   A 1 810  ? 176.448 109.790 121.954 1.00 17.70  ? 810  LEU   C CD2   1 
ATOM   4825 N N     . GLY   A 1 811  ? 176.530 114.086 124.953 1.00 10.23  ? 811  GLY   C N     1 
ATOM   4826 C CA    . GLY   A 1 811  ? 176.885 115.302 125.669 1.00 12.28  ? 811  GLY   C CA    1 
ATOM   4827 C C     . GLY   A 1 811  ? 178.242 115.160 126.331 1.00 13.53  ? 811  GLY   C C     1 
ATOM   4828 O O     . GLY   A 1 811  ? 178.933 114.159 126.134 1.00 16.03  ? 811  GLY   C O     1 
ATOM   4829 N N     . ASP   A 1 812  ? 178.611 116.150 127.138 1.00 13.98  ? 812  ASP   C N     1 
ATOM   4830 C CA    . ASP   A 1 812  ? 179.935 116.203 127.747 1.00 13.19  ? 812  ASP   C CA    1 
ATOM   4831 C C     . ASP   A 1 812  ? 180.326 114.896 128.425 1.00 15.78  ? 812  ASP   C C     1 
ATOM   4832 O O     . ASP   A 1 812  ? 181.486 114.486 128.362 1.00 18.16  ? 812  ASP   C O     1 
ATOM   4833 C CB    . ASP   A 1 812  ? 179.992 117.325 128.777 1.00 14.36  ? 812  ASP   C CB    1 
ATOM   4834 C CG    . ASP   A 1 812  ? 179.901 118.706 128.158 1.00 19.23  ? 812  ASP   C CG    1 
ATOM   4835 O OD1   . ASP   A 1 812  ? 180.077 118.833 126.967 1.00 21.10  ? 812  ASP   C OD1   1 
ATOM   4836 O OD2   . ASP   A 1 812  ? 179.642 119.630 128.885 1.00 20.97  ? 812  ASP   C OD2   1 
ATOM   4837 N N     . PHE   A 1 813  ? 179.370 114.231 129.068 1.00 14.94  ? 813  PHE   C N     1 
ATOM   4838 C CA    . PHE   A 1 813  ? 179.670 112.961 129.714 1.00 13.39  ? 813  PHE   C CA    1 
ATOM   4839 C C     . PHE   A 1 813  ? 180.064 111.907 128.684 1.00 14.50  ? 813  PHE   C C     1 
ATOM   4840 O O     . PHE   A 1 813  ? 180.934 111.073 128.937 1.00 18.48  ? 813  PHE   C O     1 
ATOM   4841 C CB    . PHE   A 1 813  ? 178.503 112.456 130.546 1.00 13.41  ? 813  PHE   C CB    1 
ATOM   4842 C CG    . PHE   A 1 813  ? 178.845 111.211 131.290 1.00 18.79  ? 813  PHE   C CG    1 
ATOM   4843 C CD1   . PHE   A 1 813  ? 179.705 111.247 132.370 1.00 16.84  ? 813  PHE   C CD1   1 
ATOM   4844 C CD2   . PHE   A 1 813  ? 178.321 110.003 130.911 1.00 14.05  ? 813  PHE   C CD2   1 
ATOM   4845 C CE1   . PHE   A 1 813  ? 180.029 110.095 133.048 1.00 5.14   ? 813  PHE   C CE1   1 
ATOM   4846 C CE2   . PHE   A 1 813  ? 178.637 108.852 131.587 1.00 17.81  ? 813  PHE   C CE2   1 
ATOM   4847 C CZ    . PHE   A 1 813  ? 179.493 108.896 132.654 1.00 0.88   ? 813  PHE   C CZ    1 
ATOM   4848 N N     . GLY   A 1 814  ? 179.392 111.909 127.537 1.00 13.12  ? 814  GLY   C N     1 
ATOM   4849 C CA    . GLY   A 1 814  ? 179.677 110.920 126.512 1.00 10.83  ? 814  GLY   C CA    1 
ATOM   4850 C C     . GLY   A 1 814  ? 181.116 111.069 126.048 1.00 10.40  ? 814  GLY   C C     1 
ATOM   4851 O O     . GLY   A 1 814  ? 181.824 110.079 125.859 1.00 12.88  ? 814  GLY   C O     1 
ATOM   4852 N N     . ILE   A 1 815  ? 181.563 112.314 125.913 1.00 12.04  ? 815  ILE   C N     1 
ATOM   4853 C CA    . ILE   A 1 815  ? 182.935 112.587 125.502 1.00 11.04  ? 815  ILE   C CA    1 
ATOM   4854 C C     . ILE   A 1 815  ? 183.918 112.095 126.548 1.00 13.69  ? 815  ILE   C C     1 
ATOM   4855 O O     . ILE   A 1 815  ? 184.924 111.469 126.213 1.00 17.43  ? 815  ILE   C O     1 
ATOM   4856 C CB    . ILE   A 1 815  ? 183.165 114.087 125.249 1.00 10.46  ? 815  ILE   C CB    1 
ATOM   4857 C CG1   . ILE   A 1 815  ? 182.310 114.575 124.080 1.00 11.82  ? 815  ILE   C CG1   1 
ATOM   4858 C CG2   . ILE   A 1 815  ? 184.630 114.371 124.998 1.00 11.97  ? 815  ILE   C CG2   1 
ATOM   4859 C CD1   . ILE   A 1 815  ? 182.551 113.884 122.752 1.00 10.18  ? 815  ILE   C CD1   1 
ATOM   4860 N N     . ARG   A 1 816  ? 183.614 112.336 127.817 1.00 13.30  ? 816  ARG   C N     1 
ATOM   4861 C CA    . ARG   A 1 816  ? 184.476 111.866 128.890 1.00 11.10  ? 816  ARG   C CA    1 
ATOM   4862 C C     . ARG   A 1 816  ? 184.741 110.368 128.760 1.00 10.34  ? 816  ARG   C C     1 
ATOM   4863 O O     . ARG   A 1 816  ? 185.868 109.915 128.967 1.00 14.15  ? 816  ARG   C O     1 
ATOM   4864 C CB    . ARG   A 1 816  ? 183.852 112.164 130.240 1.00 10.99  ? 816  ARG   C CB    1 
ATOM   4865 C CG    . ARG   A 1 816  ? 184.687 111.779 131.434 1.00 12.84  ? 816  ARG   C CG    1 
ATOM   4866 C CD    . ARG   A 1 816  ? 184.038 112.198 132.695 1.00 13.45  ? 816  ARG   C CD    1 
ATOM   4867 N NE    . ARG   A 1 816  ? 184.834 111.848 133.857 1.00 17.47  ? 816  ARG   C NE    1 
ATOM   4868 C CZ    . ARG   A 1 816  ? 184.541 112.204 135.124 1.00 20.09  ? 816  ARG   C CZ    1 
ATOM   4869 N NH1   . ARG   A 1 816  ? 183.467 112.919 135.381 1.00 19.19  ? 816  ARG   C NH1   1 
ATOM   4870 N NH2   . ARG   A 1 816  ? 185.337 111.833 136.111 1.00 23.86  ? 816  ARG   C NH2   1 
ATOM   4871 N N     . LEU   A 1 817  ? 183.709 109.601 128.400 1.00 10.12  ? 817  LEU   C N     1 
ATOM   4872 C CA    . LEU   A 1 817  ? 183.868 108.161 128.196 1.00 9.63   ? 817  LEU   C CA    1 
ATOM   4873 C C     . LEU   A 1 817  ? 184.568 107.836 126.879 1.00 12.32  ? 817  LEU   C C     1 
ATOM   4874 O O     . LEU   A 1 817  ? 185.454 106.986 126.823 1.00 14.47  ? 817  LEU   C O     1 
ATOM   4875 C CB    . LEU   A 1 817  ? 182.504 107.463 128.176 1.00 8.11   ? 817  LEU   C CB    1 
ATOM   4876 C CG    . LEU   A 1 817  ? 181.718 107.410 129.474 1.00 7.05   ? 817  LEU   C CG    1 
ATOM   4877 C CD1   . LEU   A 1 817  ? 180.339 106.865 129.171 1.00 7.21   ? 817  LEU   C CD1   1 
ATOM   4878 C CD2   . LEU   A 1 817  ? 182.433 106.522 130.476 1.00 0.07   ? 817  LEU   C CD2   1 
ATOM   4879 N N     . LEU   A 1 818  ? 184.179 108.521 125.812 1.00 11.84  ? 818  LEU   C N     1 
ATOM   4880 C CA    . LEU   A 1 818  ? 184.729 108.252 124.488 1.00 8.84   ? 818  LEU   C CA    1 
ATOM   4881 C C     . LEU   A 1 818  ? 186.235 108.472 124.466 1.00 12.62  ? 818  LEU   C C     1 
ATOM   4882 O O     . LEU   A 1 818  ? 186.971 107.741 123.799 1.00 15.77  ? 818  LEU   C O     1 
ATOM   4883 C CB    . LEU   A 1 818  ? 184.059 109.163 123.451 1.00 8.31   ? 818  LEU   C CB    1 
ATOM   4884 C CG    . LEU   A 1 818  ? 184.449 108.956 121.980 1.00 6.82   ? 818  LEU   C CG    1 
ATOM   4885 C CD1   . LEU   A 1 818  ? 184.043 107.564 121.522 1.00 8.05   ? 818  LEU   C CD1   1 
ATOM   4886 C CD2   . LEU   A 1 818  ? 183.766 110.022 121.140 1.00 6.58   ? 818  LEU   C CD2   1 
ATOM   4887 N N     . CYS   A 1 819  ? 186.691 109.475 125.212 1.00 13.88  ? 819  CYS   C N     1 
ATOM   4888 C CA    . CYS   A 1 819  ? 188.105 109.814 125.271 1.00 12.80  ? 819  CYS   C CA    1 
ATOM   4889 C C     . CYS   A 1 819  ? 188.947 108.715 125.898 1.00 17.03  ? 819  CYS   C C     1 
ATOM   4890 O O     . CYS   A 1 819  ? 190.164 108.690 125.717 1.00 19.51  ? 819  CYS   C O     1 
ATOM   4891 C CB    . CYS   A 1 819  ? 188.315 111.110 126.041 1.00 11.25  ? 819  CYS   C CB    1 
ATOM   4892 S SG    . CYS   A 1 819  ? 187.672 112.554 125.193 1.00 19.50  ? 819  CYS   C SG    1 
ATOM   4893 N N     . VAL   A 1 820  ? 188.321 107.801 126.630 1.00 16.06  ? 820  VAL   C N     1 
ATOM   4894 C CA    . VAL   A 1 820  ? 189.074 106.718 127.239 1.00 16.11  ? 820  VAL   C CA    1 
ATOM   4895 C C     . VAL   A 1 820  ? 189.595 105.793 126.152 1.00 17.51  ? 820  VAL   C C     1 
ATOM   4896 O O     . VAL   A 1 820  ? 190.741 105.348 126.198 1.00 21.29  ? 820  VAL   C O     1 
ATOM   4897 C CB    . VAL   A 1 820  ? 188.211 105.934 128.243 1.00 14.10  ? 820  VAL   C CB    1 
ATOM   4898 C CG1   . VAL   A 1 820  ? 188.968 104.710 128.747 1.00 14.85  ? 820  VAL   C CG1   1 
ATOM   4899 C CG2   . VAL   A 1 820  ? 187.841 106.847 129.402 1.00 15.03  ? 820  VAL   C CG2   1 
ATOM   4900 N N     . GLY   A 1 821  ? 188.746 105.502 125.172 1.00 15.89  ? 821  GLY   C N     1 
ATOM   4901 C CA    . GLY   A 1 821  ? 189.139 104.667 124.048 1.00 15.20  ? 821  GLY   C CA    1 
ATOM   4902 C C     . GLY   A 1 821  ? 190.133 105.400 123.152 1.00 17.46  ? 821  GLY   C C     1 
ATOM   4903 O O     . GLY   A 1 821  ? 191.096 104.815 122.666 1.00 20.90  ? 821  GLY   C O     1 
ATOM   4904 N N     . LEU   A 1 822  ? 189.912 106.697 122.951 1.00 16.86  ? 822  LEU   C N     1 
ATOM   4905 C CA    . LEU   A 1 822  ? 190.765 107.480 122.057 1.00 16.63  ? 822  LEU   C CA    1 
ATOM   4906 C C     . LEU   A 1 822  ? 192.201 107.569 122.566 1.00 19.89  ? 822  LEU   C C     1 
ATOM   4907 O O     . LEU   A 1 822  ? 193.143 107.600 121.776 1.00 22.57  ? 822  LEU   C O     1 
ATOM   4908 C CB    . LEU   A 1 822  ? 190.194 108.891 121.875 1.00 14.75  ? 822  LEU   C CB    1 
ATOM   4909 C CG    . LEU   A 1 822  ? 188.847 108.987 121.122 1.00 11.88  ? 822  LEU   C CG    1 
ATOM   4910 C CD1   . LEU   A 1 822  ? 188.314 110.410 121.209 1.00 11.96  ? 822  LEU   C CD1   1 
ATOM   4911 C CD2   . LEU   A 1 822  ? 189.040 108.594 119.673 1.00 9.87   ? 822  LEU   C CD2   1 
ATOM   4912 N N     . LYS   A 1 823  ? 192.375 107.589 123.884 1.00 19.48  ? 823  LYS   C N     1 
ATOM   4913 C CA    . LYS   A 1 823  ? 193.707 107.668 124.480 1.00 18.76  ? 823  LYS   C CA    1 
ATOM   4914 C C     . LYS   A 1 823  ? 194.363 106.296 124.628 1.00 21.61  ? 823  LYS   C C     1 
ATOM   4915 O O     . LYS   A 1 823  ? 195.500 106.197 125.093 1.00 26.09  ? 823  LYS   C O     1 
ATOM   4916 C CB    . LYS   A 1 823  ? 193.637 108.325 125.862 1.00 17.79  ? 823  LYS   C CB    1 
ATOM   4917 C CG    . LYS   A 1 823  ? 193.239 109.793 125.863 1.00 22.38  ? 823  LYS   C CG    1 
ATOM   4918 C CD    . LYS   A 1 823  ? 193.319 110.407 127.271 1.00 24.29  ? 823  LYS   C CD    1 
ATOM   4919 C CE    . LYS   A 1 823  ? 192.152 109.945 128.159 1.00 22.85  ? 823  LYS   C CE    1 
ATOM   4920 N NZ    . LYS   A 1 823  ? 192.130 110.655 129.475 1.00 22.28  ? 823  LYS   C NZ    1 
ATOM   4921 N N     . HIS   A 1 824  ? 193.633 105.240 124.293 1.00 22.00  ? 824  HIS   C N     1 
ATOM   4922 C CA    . HIS   A 1 824  ? 194.102 103.878 124.506 1.00 24.37  ? 824  HIS   C CA    1 
ATOM   4923 C C     . HIS   A 1 824  ? 195.075 103.432 123.422 1.00 25.52  ? 824  HIS   C C     1 
ATOM   4924 O O     . HIS   A 1 824  ? 194.937 103.786 122.250 1.00 27.67  ? 824  HIS   C O     1 
ATOM   4925 C CB    . HIS   A 1 824  ? 192.912 102.917 124.574 1.00 25.34  ? 824  HIS   C CB    1 
ATOM   4926 C CG    . HIS   A 1 824  ? 193.223 101.613 125.246 1.00 29.26  ? 824  HIS   C CG    1 
ATOM   4927 N ND1   . HIS   A 1 824  ? 193.859 100.573 124.606 1.00 29.36  ? 824  HIS   C ND1   1 
ATOM   4928 C CD2   . HIS   A 1 824  ? 192.986 101.189 126.508 1.00 34.35  ? 824  HIS   C CD2   1 
ATOM   4929 C CE1   . HIS   A 1 824  ? 194.001 99.566  125.444 1.00 32.29  ? 824  HIS   C CE1   1 
ATOM   4930 N NE2   . HIS   A 1 824  ? 193.480 99.915  126.606 1.00 37.62  ? 824  HIS   C NE2   1 
ATOM   4931 N N     . LEU   A 1 825  ? 196.049 102.624 123.806 1.00 27.25  ? 825  LEU   C N     1 
ATOM   4932 C CA    . LEU   A 1 825  ? 196.973 102.069 122.831 1.00 28.95  ? 825  LEU   C CA    1 
ATOM   4933 C C     . LEU   A 1 825  ? 196.219 101.144 121.893 1.00 30.40  ? 825  LEU   C C     1 
ATOM   4934 O O     . LEU   A 1 825  ? 195.199 100.566 122.266 1.00 31.33  ? 825  LEU   C O     1 
ATOM   4935 C CB    . LEU   A 1 825  ? 198.108 101.304 123.522 1.00 31.91  ? 825  LEU   C CB    1 
ATOM   4936 C CG    . LEU   A 1 825  ? 199.063 102.140 124.407 1.00 36.51  ? 825  LEU   C CG    1 
ATOM   4937 C CD1   . LEU   A 1 825  ? 200.037 101.202 125.104 1.00 38.02  ? 825  LEU   C CD1   1 
ATOM   4938 C CD2   . LEU   A 1 825  ? 199.819 103.157 123.548 1.00 36.17  ? 825  LEU   C CD2   1 
ATOM   4939 N N     . LEU   A 1 826  ? 196.707 101.031 120.664 1.00 29.53  ? 826  LEU   C N     1 
ATOM   4940 C CA    . LEU   A 1 826  ? 196.087 100.225 119.611 1.00 29.31  ? 826  LEU   C CA    1 
ATOM   4941 C C     . LEU   A 1 826  ? 194.832 100.883 119.039 1.00 27.93  ? 826  LEU   C C     1 
ATOM   4942 O O     . LEU   A 1 826  ? 194.188 100.323 118.153 1.00 29.08  ? 826  LEU   C O     1 
ATOM   4943 C CB    . LEU   A 1 826  ? 195.722 98.819  120.136 1.00 30.96  ? 826  LEU   C CB    1 
ATOM   4944 C CG    . LEU   A 1 826  ? 196.856 98.016  120.812 1.00 38.11  ? 826  LEU   C CG    1 
ATOM   4945 C CD1   . LEU   A 1 826  ? 196.288 96.710  121.340 1.00 35.39  ? 826  LEU   C CD1   1 
ATOM   4946 C CD2   . LEU   A 1 826  ? 197.971 97.749  119.806 1.00 39.11  ? 826  LEU   C CD2   1 
ATOM   4947 N N     . CYS   A 1 827  ? 194.531 102.104 119.467 1.00 24.54  ? 827  CYS   C N     1 
ATOM   4948 C CA    . CYS   A 1 827  ? 193.460 102.852 118.834 1.00 20.15  ? 827  CYS   C CA    1 
ATOM   4949 C C     . CYS   A 1 827  ? 194.044 103.621 117.662 1.00 23.28  ? 827  CYS   C C     1 
ATOM   4950 O O     . CYS   A 1 827  ? 194.895 104.492 117.845 1.00 24.92  ? 827  CYS   C O     1 
ATOM   4951 C CB    . CYS   A 1 827  ? 192.811 103.818 119.813 1.00 18.42  ? 827  CYS   C CB    1 
ATOM   4952 S SG    . CYS   A 1 827  ? 191.482 104.784 119.101 1.00 21.02  ? 827  CYS   C SG    1 
ATOM   4953 N N     . ASN   A 1 828  ? 193.620 103.274 116.454 1.00 22.20  ? 828  ASN   C N     1 
ATOM   4954 C CA    . ASN   A 1 828  ? 194.200 103.840 115.244 1.00 18.69  ? 828  ASN   C CA    1 
ATOM   4955 C C     . ASN   A 1 828  ? 193.299 104.863 114.571 1.00 14.65  ? 828  ASN   C C     1 
ATOM   4956 O O     . ASN   A 1 828  ? 193.492 105.194 113.403 1.00 13.76  ? 828  ASN   C O     1 
ATOM   4957 C CB    . ASN   A 1 828  ? 194.554 102.732 114.269 1.00 18.80  ? 828  ASN   C CB    1 
ATOM   4958 C CG    . ASN   A 1 828  ? 195.691 101.866 114.757 1.00 25.43  ? 828  ASN   C CG    1 
ATOM   4959 O OD1   . ASN   A 1 828  ? 196.614 102.348 115.425 1.00 25.19  ? 828  ASN   C OD1   1 
ATOM   4960 N ND2   . ASN   A 1 828  ? 195.647 100.600 114.428 1.00 29.31  ? 828  ASN   C ND2   1 
ATOM   4961 N N     . LEU   A 1 829  ? 192.307 105.360 115.295 1.00 12.98  ? 829  LEU   C N     1 
ATOM   4962 C CA    . LEU   A 1 829  ? 191.366 106.305 114.706 1.00 7.73   ? 829  LEU   C CA    1 
ATOM   4963 C C     . LEU   A 1 829  ? 192.102 107.560 114.253 1.00 8.40   ? 829  LEU   C C     1 
ATOM   4964 O O     . LEU   A 1 829  ? 192.891 108.127 115.007 1.00 13.52  ? 829  LEU   C O     1 
ATOM   4965 C CB    . LEU   A 1 829  ? 190.293 106.680 115.737 1.00 6.00   ? 829  LEU   C CB    1 
ATOM   4966 C CG    . LEU   A 1 829  ? 189.061 107.387 115.184 1.00 5.53   ? 829  LEU   C CG    1 
ATOM   4967 C CD1   . LEU   A 1 829  ? 188.220 106.393 114.401 1.00 1.54   ? 829  LEU   C CD1   1 
ATOM   4968 C CD2   . LEU   A 1 829  ? 188.270 107.987 116.313 1.00 5.80   ? 829  LEU   C CD2   1 
ATOM   4969 N N     . LYS   A 1 830  ? 191.841 107.998 113.020 1.00 7.09   ? 830  LYS   C N     1 
ATOM   4970 C CA    . LYS   A 1 830  ? 192.508 109.176 112.476 1.00 5.83   ? 830  LYS   C CA    1 
ATOM   4971 C C     . LYS   A 1 830  ? 191.591 110.384 112.342 1.00 0.83   ? 830  LYS   C C     1 
ATOM   4972 O O     . LYS   A 1 830  ? 192.025 111.520 112.538 1.00 1.41   ? 830  LYS   C O     1 
ATOM   4973 C CB    . LYS   A 1 830  ? 193.123 108.866 111.114 1.00 5.66   ? 830  LYS   C CB    1 
ATOM   4974 C CG    . LYS   A 1 830  ? 194.263 107.865 111.160 1.00 9.84   ? 830  LYS   C CG    1 
ATOM   4975 C CD    . LYS   A 1 830  ? 194.867 107.645 109.782 1.00 9.95   ? 830  LYS   C CD    1 
ATOM   4976 C CE    . LYS   A 1 830  ? 195.981 106.614 109.833 1.00 13.44  ? 830  LYS   C CE    1 
ATOM   4977 N NZ    . LYS   A 1 830  ? 196.579 106.377 108.493 1.00 19.51  ? 830  LYS   C NZ    1 
ATOM   4978 N N     . LYS   A 1 831  ? 190.332 110.147 111.991 1.00 0.98   ? 831  LYS   C N     1 
ATOM   4979 C CA    . LYS   A 1 831  ? 189.408 111.252 111.762 1.00 0.48   ? 831  LYS   C CA    1 
ATOM   4980 C C     . LYS   A 1 831  ? 188.141 111.123 112.589 1.00 0.02   ? 831  LYS   C C     1 
ATOM   4981 O O     . LYS   A 1 831  ? 187.395 110.153 112.454 1.00 0.00   ? 831  LYS   C O     1 
ATOM   4982 C CB    . LYS   A 1 831  ? 189.070 111.345 110.277 1.00 0.93   ? 831  LYS   C CB    1 
ATOM   4983 C CG    . LYS   A 1 831  ? 188.117 112.470 109.905 1.00 6.07   ? 831  LYS   C CG    1 
ATOM   4984 C CD    . LYS   A 1 831  ? 188.178 112.779 108.399 1.00 4.54   ? 831  LYS   C CD    1 
ATOM   4985 C CE    . LYS   A 1 831  ? 187.509 111.696 107.561 1.00 1.57   ? 831  LYS   C CE    1 
ATOM   4986 N NZ    . LYS   A 1 831  ? 187.558 112.014 106.099 1.00 12.89  ? 831  LYS   C NZ    1 
ATOM   4987 N N     . LEU   A 1 832  ? 187.898 112.107 113.447 1.00 0.05   ? 832  LEU   C N     1 
ATOM   4988 C CA    . LEU   A 1 832  ? 186.739 112.059 114.330 1.00 0.02   ? 832  LEU   C CA    1 
ATOM   4989 C C     . LEU   A 1 832  ? 185.837 113.282 114.185 1.00 0.00   ? 832  LEU   C C     1 
ATOM   4990 O O     . LEU   A 1 832  ? 186.284 114.419 114.338 1.00 0.00   ? 832  LEU   C O     1 
ATOM   4991 C CB    . LEU   A 1 832  ? 187.215 111.935 115.783 1.00 0.00   ? 832  LEU   C CB    1 
ATOM   4992 C CG    . LEU   A 1 832  ? 186.132 111.937 116.869 1.00 0.00   ? 832  LEU   C CG    1 
ATOM   4993 C CD1   . LEU   A 1 832  ? 185.257 110.688 116.753 1.00 0.00   ? 832  LEU   C CD1   1 
ATOM   4994 C CD2   . LEU   A 1 832  ? 186.804 111.995 118.226 1.00 0.03   ? 832  LEU   C CD2   1 
ATOM   4995 N N     . TRP   A 1 833  ? 184.560 113.030 113.911 1.00 0.03   ? 833  TRP   C N     1 
ATOM   4996 C CA    . TRP   A 1 833  ? 183.579 114.107 113.783 1.00 0.00   ? 833  TRP   C CA    1 
ATOM   4997 C C     . TRP   A 1 833  ? 182.662 114.174 114.999 1.00 0.00   ? 833  TRP   C C     1 
ATOM   4998 O O     . TRP   A 1 833  ? 181.926 113.228 115.280 1.00 0.00   ? 833  TRP   C O     1 
ATOM   4999 C CB    . TRP   A 1 833  ? 182.708 113.895 112.551 1.00 0.02   ? 833  TRP   C CB    1 
ATOM   5000 C CG    . TRP   A 1 833  ? 183.424 113.944 111.252 1.00 0.08   ? 833  TRP   C CG    1 
ATOM   5001 C CD1   . TRP   A 1 833  ? 184.170 112.957 110.696 1.00 3.00   ? 833  TRP   C CD1   1 
ATOM   5002 C CD2   . TRP   A 1 833  ? 183.455 115.040 110.322 1.00 0.02   ? 833  TRP   C CD2   1 
ATOM   5003 N NE1   . TRP   A 1 833  ? 184.662 113.364 109.488 1.00 0.06   ? 833  TRP   C NE1   1 
ATOM   5004 C CE2   . TRP   A 1 833  ? 184.222 114.628 109.236 1.00 0.03   ? 833  TRP   C CE2   1 
ATOM   5005 C CE3   . TRP   A 1 833  ? 182.869 116.303 110.306 1.00 0.07   ? 833  TRP   C CE3   1 
ATOM   5006 C CZ2   . TRP   A 1 833  ? 184.460 115.451 108.159 1.00 0.04   ? 833  TRP   C CZ2   1 
ATOM   5007 C CZ3   . TRP   A 1 833  ? 183.103 117.132 109.224 1.00 0.01   ? 833  TRP   C CZ3   1 
ATOM   5008 C CH2   . TRP   A 1 833  ? 183.871 116.712 108.172 1.00 1.91   ? 833  TRP   C CH2   1 
ATOM   5009 N N     . LEU   A 1 834  ? 182.688 115.304 115.703 1.00 0.04   ? 834  LEU   C N     1 
ATOM   5010 C CA    . LEU   A 1 834  ? 181.852 115.514 116.885 1.00 0.03   ? 834  LEU   C CA    1 
ATOM   5011 C C     . LEU   A 1 834  ? 180.973 116.746 116.715 1.00 0.01   ? 834  LEU   C C     1 
ATOM   5012 O O     . LEU   A 1 834  ? 180.713 117.473 117.675 1.00 0.35   ? 834  LEU   C O     1 
ATOM   5013 C CB    . LEU   A 1 834  ? 182.725 115.695 118.128 1.00 0.14   ? 834  LEU   C CB    1 
ATOM   5014 C CG    . LEU   A 1 834  ? 183.651 114.541 118.471 1.00 0.01   ? 834  LEU   C CG    1 
ATOM   5015 C CD1   . LEU   A 1 834  ? 184.576 114.968 119.588 1.00 0.01   ? 834  LEU   C CD1   1 
ATOM   5016 C CD2   . LEU   A 1 834  ? 182.839 113.327 118.876 1.00 0.00   ? 834  LEU   C CD2   1 
ATOM   5017 N N     . VAL   A 1 835  ? 180.533 116.980 115.490 1.00 0.02   ? 835  VAL   C N     1 
ATOM   5018 C CA    . VAL   A 1 835  ? 179.729 118.144 115.150 1.00 0.00   ? 835  VAL   C CA    1 
ATOM   5019 C C     . VAL   A 1 835  ? 178.320 118.059 115.718 1.00 0.02   ? 835  VAL   C C     1 
ATOM   5020 O O     . VAL   A 1 835  ? 177.675 117.014 115.650 1.00 0.00   ? 835  VAL   C O     1 
ATOM   5021 C CB    . VAL   A 1 835  ? 179.671 118.297 113.622 1.00 0.11   ? 835  VAL   C CB    1 
ATOM   5022 C CG1   . VAL   A 1 835  ? 178.739 119.418 113.235 1.00 0.03   ? 835  VAL   C CG1   1 
ATOM   5023 C CG2   . VAL   A 1 835  ? 181.065 118.572 113.111 1.00 0.01   ? 835  VAL   C CG2   1 
ATOM   5024 N N     . SER   A 1 836  ? 177.852 119.165 116.286 1.00 0.26   ? 836  SER   C N     1 
ATOM   5025 C CA    . SER   A 1 836  ? 176.504 119.258 116.847 1.00 0.03   ? 836  SER   C CA    1 
ATOM   5026 C C     . SER   A 1 836  ? 176.195 118.155 117.853 1.00 2.75   ? 836  SER   C C     1 
ATOM   5027 O O     . SER   A 1 836  ? 175.174 117.483 117.741 1.00 8.68   ? 836  SER   C O     1 
ATOM   5028 C CB    . SER   A 1 836  ? 175.464 119.207 115.740 1.00 2.94   ? 836  SER   C CB    1 
ATOM   5029 O OG    . SER   A 1 836  ? 175.612 120.269 114.843 1.00 5.64   ? 836  SER   C OG    1 
ATOM   5030 N N     . CYS   A 1 837  ? 177.066 117.970 118.841 1.00 9.41   ? 837  CYS   C N     1 
ATOM   5031 C CA    . CYS   A 1 837  ? 176.863 116.921 119.837 1.00 0.02   ? 837  CYS   C CA    1 
ATOM   5032 C C     . CYS   A 1 837  ? 176.501 117.484 121.205 1.00 12.33  ? 837  CYS   C C     1 
ATOM   5033 O O     . CYS   A 1 837  ? 176.685 116.827 122.225 1.00 15.45  ? 837  CYS   C O     1 
ATOM   5034 C CB    . CYS   A 1 837  ? 178.101 116.041 119.957 1.00 0.99   ? 837  CYS   C CB    1 
ATOM   5035 S SG    . CYS   A 1 837  ? 178.405 115.042 118.512 1.00 7.30   ? 837  CYS   C SG    1 
ATOM   5036 N N     . CYS   A 1 838  ? 175.979 118.702 121.228 1.00 14.88  ? 838  CYS   C N     1 
ATOM   5037 C CA    . CYS   A 1 838  ? 175.556 119.332 122.472 1.00 14.36  ? 838  CYS   C CA    1 
ATOM   5038 C C     . CYS   A 1 838  ? 176.689 119.407 123.483 1.00 14.85  ? 838  CYS   C C     1 
ATOM   5039 O O     . CYS   A 1 838  ? 176.483 119.136 124.666 1.00 20.20  ? 838  CYS   C O     1 
ATOM   5040 C CB    . CYS   A 1 838  ? 174.402 118.555 123.099 1.00 18.29  ? 838  CYS   C CB    1 
ATOM   5041 S SG    . CYS   A 1 838  ? 172.996 118.329 122.007 1.00 33.09  ? 838  CYS   C SG    1 
ATOM   5042 N N     . LEU   A 1 839  ? 177.877 119.781 123.021 1.00 14.19  ? 839  LEU   C N     1 
ATOM   5043 C CA    . LEU   A 1 839  ? 179.028 119.873 123.907 1.00 14.23  ? 839  LEU   C CA    1 
ATOM   5044 C C     . LEU   A 1 839  ? 179.213 121.279 124.436 1.00 12.94  ? 839  LEU   C C     1 
ATOM   5045 O O     . LEU   A 1 839  ? 178.870 122.256 123.765 1.00 14.23  ? 839  LEU   C O     1 
ATOM   5046 C CB    . LEU   A 1 839  ? 180.303 119.462 123.170 1.00 13.79  ? 839  LEU   C CB    1 
ATOM   5047 C CG    . LEU   A 1 839  ? 180.294 118.096 122.522 1.00 12.45  ? 839  LEU   C CG    1 
ATOM   5048 C CD1   . LEU   A 1 839  ? 181.633 117.869 121.838 1.00 18.04  ? 839  LEU   C CD1   1 
ATOM   5049 C CD2   . LEU   A 1 839  ? 180.014 117.040 123.565 1.00 14.53  ? 839  LEU   C CD2   1 
ATOM   5050 N N     . THR   A 1 840  ? 179.802 121.385 125.618 1.00 13.15  ? 840  THR   C N     1 
ATOM   5051 C CA    . THR   A 1 840  ? 180.155 122.687 126.169 1.00 12.54  ? 840  THR   C CA    1 
ATOM   5052 C C     . THR   A 1 840  ? 181.634 122.724 126.490 1.00 14.96  ? 840  THR   C C     1 
ATOM   5053 O O     . THR   A 1 840  ? 182.343 121.731 126.312 1.00 17.81  ? 840  THR   C O     1 
ATOM   5054 C CB    . THR   A 1 840  ? 179.366 123.025 127.443 1.00 17.62  ? 840  THR   C CB    1 
ATOM   5055 O OG1   . THR   A 1 840  ? 179.870 122.254 128.539 1.00 21.27  ? 840  THR   C OG1   1 
ATOM   5056 C CG2   . THR   A 1 840  ? 177.894 122.729 127.253 1.00 22.40  ? 840  THR   C CG2   1 
ATOM   5057 N N     . SER   A 1 841  ? 182.102 123.867 126.972 1.00 14.26  ? 841  SER   C N     1 
ATOM   5058 C CA    . SER   A 1 841  ? 183.515 124.056 127.267 1.00 14.89  ? 841  SER   C CA    1 
ATOM   5059 C C     . SER   A 1 841  ? 184.017 123.077 128.320 1.00 19.25  ? 841  SER   C C     1 
ATOM   5060 O O     . SER   A 1 841  ? 185.221 122.850 128.444 1.00 22.07  ? 841  SER   C O     1 
ATOM   5061 C CB    . SER   A 1 841  ? 183.753 125.474 127.739 1.00 15.22  ? 841  SER   C CB    1 
ATOM   5062 O OG    . SER   A 1 841  ? 183.131 125.696 128.971 1.00 19.12  ? 841  SER   C OG    1 
ATOM   5063 N N     . ALA   A 1 842  ? 183.097 122.480 129.069 1.00 19.30  ? 842  ALA   C N     1 
ATOM   5064 C CA    . ALA   A 1 842  ? 183.451 121.536 130.118 1.00 17.98  ? 842  ALA   C CA    1 
ATOM   5065 C C     . ALA   A 1 842  ? 184.183 120.317 129.562 1.00 20.20  ? 842  ALA   C C     1 
ATOM   5066 O O     . ALA   A 1 842  ? 184.957 119.680 130.276 1.00 21.53  ? 842  ALA   C O     1 
ATOM   5067 C CB    . ALA   A 1 842  ? 182.205 121.092 130.861 1.00 18.11  ? 842  ALA   C CB    1 
ATOM   5068 N N     . CYS   A 1 843  ? 183.927 119.970 128.300 1.00 20.62  ? 843  CYS   C N     1 
ATOM   5069 C CA    . CYS   A 1 843  ? 184.518 118.773 127.707 1.00 17.90  ? 843  CYS   C CA    1 
ATOM   5070 C C     . CYS   A 1 843  ? 185.856 119.053 127.038 1.00 19.12  ? 843  CYS   C C     1 
ATOM   5071 O O     . CYS   A 1 843  ? 186.506 118.134 126.534 1.00 19.75  ? 843  CYS   C O     1 
ATOM   5072 C CB    . CYS   A 1 843  ? 183.596 118.177 126.655 1.00 15.46  ? 843  CYS   C CB    1 
ATOM   5073 S SG    . CYS   A 1 843  ? 183.537 119.127 125.137 1.00 21.25  ? 843  CYS   C SG    1 
ATOM   5074 N N     . CYS   A 1 844  ? 186.261 120.320 126.998 1.00 19.73  ? 844  CYS   C N     1 
ATOM   5075 C CA    . CYS   A 1 844  ? 187.480 120.677 126.289 1.00 17.30  ? 844  CYS   C CA    1 
ATOM   5076 C C     . CYS   A 1 844  ? 188.712 120.087 126.936 1.00 18.81  ? 844  CYS   C C     1 
ATOM   5077 O O     . CYS   A 1 844  ? 189.705 119.829 126.258 1.00 21.14  ? 844  CYS   C O     1 
ATOM   5078 C CB    . CYS   A 1 844  ? 187.637 122.183 126.195 1.00 17.70  ? 844  CYS   C CB    1 
ATOM   5079 S SG    . CYS   A 1 844  ? 186.500 122.941 125.056 1.00 21.97  ? 844  CYS   C SG    1 
ATOM   5080 N N     . GLN   A 1 845  ? 188.663 119.867 128.241 1.00 19.31  ? 845  GLN   C N     1 
ATOM   5081 C CA    . GLN   A 1 845  ? 189.815 119.316 128.929 1.00 20.10  ? 845  GLN   C CA    1 
ATOM   5082 C C     . GLN   A 1 845  ? 190.117 117.899 128.458 1.00 24.66  ? 845  GLN   C C     1 
ATOM   5083 O O     . GLN   A 1 845  ? 191.282 117.511 128.357 1.00 25.22  ? 845  GLN   C O     1 
ATOM   5084 C CB    . GLN   A 1 845  ? 189.594 119.334 130.439 1.00 19.33  ? 845  GLN   C CB    1 
ATOM   5085 C CG    . GLN   A 1 845  ? 190.805 118.912 131.244 1.00 21.90  ? 845  GLN   C CG    1 
ATOM   5086 C CD    . GLN   A 1 845  ? 191.974 119.851 131.061 1.00 24.29  ? 845  GLN   C CD    1 
ATOM   5087 O OE1   . GLN   A 1 845  ? 191.848 121.063 131.255 1.00 26.04  ? 845  GLN   C OE1   1 
ATOM   5088 N NE2   . GLN   A 1 845  ? 193.121 119.300 130.688 1.00 24.73  ? 845  GLN   C NE2   1 
ATOM   5089 N N     . ASP   A 1 846  ? 189.078 117.126 128.157 1.00 22.80  ? 846  ASP   C N     1 
ATOM   5090 C CA    . ASP   A 1 846  ? 189.289 115.744 127.754 1.00 19.24  ? 846  ASP   C CA    1 
ATOM   5091 C C     . ASP   A 1 846  ? 189.663 115.658 126.285 1.00 20.72  ? 846  ASP   C C     1 
ATOM   5092 O O     . ASP   A 1 846  ? 190.506 114.847 125.903 1.00 22.95  ? 846  ASP   C O     1 
ATOM   5093 C CB    . ASP   A 1 846  ? 188.044 114.906 128.020 1.00 16.59  ? 846  ASP   C CB    1 
ATOM   5094 C CG    . ASP   A 1 846  ? 187.738 114.761 129.488 1.00 20.82  ? 846  ASP   C CG    1 
ATOM   5095 O OD1   . ASP   A 1 846  ? 188.602 114.340 130.220 1.00 19.91  ? 846  ASP   C OD1   1 
ATOM   5096 O OD2   . ASP   A 1 846  ? 186.638 115.070 129.874 1.00 21.41  ? 846  ASP   C OD2   1 
ATOM   5097 N N     . LEU   A 1 847  ? 189.071 116.518 125.465 1.00 20.14  ? 847  LEU   C N     1 
ATOM   5098 C CA    . LEU   A 1 847  ? 189.417 116.529 124.053 1.00 17.83  ? 847  LEU   C CA    1 
ATOM   5099 C C     . LEU   A 1 847  ? 190.857 116.992 123.886 1.00 19.95  ? 847  LEU   C C     1 
ATOM   5100 O O     . LEU   A 1 847  ? 191.589 116.482 123.035 1.00 22.49  ? 847  LEU   C O     1 
ATOM   5101 C CB    . LEU   A 1 847  ? 188.475 117.453 123.275 1.00 14.74  ? 847  LEU   C CB    1 
ATOM   5102 C CG    . LEU   A 1 847  ? 187.018 116.990 123.132 1.00 13.37  ? 847  LEU   C CG    1 
ATOM   5103 C CD1   . LEU   A 1 847  ? 186.189 118.130 122.554 1.00 12.67  ? 847  LEU   C CD1   1 
ATOM   5104 C CD2   . LEU   A 1 847  ? 186.948 115.765 122.222 1.00 13.46  ? 847  LEU   C CD2   1 
ATOM   5105 N N     . ALA   A 1 848  ? 191.266 117.956 124.709 1.00 18.94  ? 848  ALA   C N     1 
ATOM   5106 C CA    . ALA   A 1 848  ? 192.619 118.485 124.660 1.00 18.73  ? 848  ALA   C CA    1 
ATOM   5107 C C     . ALA   A 1 848  ? 193.635 117.409 125.027 1.00 21.14  ? 848  ALA   C C     1 
ATOM   5108 O O     . ALA   A 1 848  ? 194.696 117.312 124.407 1.00 24.07  ? 848  ALA   C O     1 
ATOM   5109 C CB    . ALA   A 1 848  ? 192.740 119.674 125.587 1.00 21.19  ? 848  ALA   C CB    1 
ATOM   5110 N N     . SER   A 1 849  ? 193.289 116.574 126.008 1.00 22.54  ? 849  SER   C N     1 
ATOM   5111 C CA    . SER   A 1 849  ? 194.162 115.480 126.415 1.00 24.01  ? 849  SER   C CA    1 
ATOM   5112 C C     . SER   A 1 849  ? 194.344 114.478 125.283 1.00 25.03  ? 849  SER   C C     1 
ATOM   5113 O O     . SER   A 1 849  ? 195.442 113.950 125.089 1.00 26.62  ? 849  SER   C O     1 
ATOM   5114 C CB    . SER   A 1 849  ? 193.599 114.777 127.633 1.00 23.32  ? 849  SER   C CB    1 
ATOM   5115 O OG    . SER   A 1 849  ? 193.615 115.620 128.753 1.00 26.25  ? 849  SER   C OG    1 
ATOM   5116 N N     . VAL   A 1 850  ? 193.282 114.233 124.517 1.00 23.64  ? 850  VAL   C N     1 
ATOM   5117 C CA    . VAL   A 1 850  ? 193.376 113.315 123.390 1.00 19.30  ? 850  VAL   C CA    1 
ATOM   5118 C C     . VAL   A 1 850  ? 194.319 113.860 122.329 1.00 22.55  ? 850  VAL   C C     1 
ATOM   5119 O O     . VAL   A 1 850  ? 195.173 113.135 121.825 1.00 24.26  ? 850  VAL   C O     1 
ATOM   5120 C CB    . VAL   A 1 850  ? 191.996 113.057 122.753 1.00 15.71  ? 850  VAL   C CB    1 
ATOM   5121 C CG1   . VAL   A 1 850  ? 192.157 112.252 121.473 1.00 15.98  ? 850  VAL   C CG1   1 
ATOM   5122 C CG2   . VAL   A 1 850  ? 191.119 112.300 123.726 1.00 22.99  ? 850  VAL   C CG2   1 
ATOM   5123 N N     . LEU   A 1 851  ? 194.197 115.145 122.002 1.00 23.90  ? 851  LEU   C N     1 
ATOM   5124 C CA    . LEU   A 1 851  ? 195.075 115.727 120.991 1.00 20.82  ? 851  LEU   C CA    1 
ATOM   5125 C C     . LEU   A 1 851  ? 196.535 115.632 121.409 1.00 22.58  ? 851  LEU   C C     1 
ATOM   5126 O O     . LEU   A 1 851  ? 197.411 115.361 120.586 1.00 25.35  ? 851  LEU   C O     1 
ATOM   5127 C CB    . LEU   A 1 851  ? 194.730 117.205 120.755 1.00 16.74  ? 851  LEU   C CB    1 
ATOM   5128 C CG    . LEU   A 1 851  ? 193.408 117.508 120.040 1.00 15.95  ? 851  LEU   C CG    1 
ATOM   5129 C CD1   . LEU   A 1 851  ? 193.159 119.015 120.082 1.00 15.49  ? 851  LEU   C CD1   1 
ATOM   5130 C CD2   . LEU   A 1 851  ? 193.486 117.015 118.601 1.00 15.19  ? 851  LEU   C CD2   1 
ATOM   5131 N N     . SER   A 1 852  ? 196.790 115.830 122.696 1.00 23.78  ? 852  SER   C N     1 
ATOM   5132 C CA    . SER   A 1 852  ? 198.141 115.768 123.231 1.00 25.22  ? 852  SER   C CA    1 
ATOM   5133 C C     . SER   A 1 852  ? 198.746 114.365 123.188 1.00 26.39  ? 852  SER   C C     1 
ATOM   5134 O O     . SER   A 1 852  ? 199.901 114.198 122.790 1.00 26.42  ? 852  SER   C O     1 
ATOM   5135 C CB    . SER   A 1 852  ? 198.146 116.264 124.661 1.00 28.66  ? 852  SER   C CB    1 
ATOM   5136 O OG    . SER   A 1 852  ? 199.436 116.219 125.206 1.00 32.73  ? 852  SER   C OG    1 
ATOM   5137 N N     . THR   A 1 853  ? 197.984 113.356 123.619 1.00 27.94  ? 853  THR   C N     1 
ATOM   5138 C CA    . THR   A 1 853  ? 198.540 112.011 123.749 1.00 27.76  ? 853  THR   C CA    1 
ATOM   5139 C C     . THR   A 1 853  ? 198.276 111.082 122.561 1.00 29.25  ? 853  THR   C C     1 
ATOM   5140 O O     . THR   A 1 853  ? 198.985 110.088 122.395 1.00 29.31  ? 853  THR   C O     1 
ATOM   5141 C CB    . THR   A 1 853  ? 198.002 111.326 125.017 1.00 29.02  ? 853  THR   C CB    1 
ATOM   5142 O OG1   . THR   A 1 853  ? 196.586 111.146 124.899 1.00 26.70  ? 853  THR   C OG1   1 
ATOM   5143 C CG2   . THR   A 1 853  ? 198.295 112.183 126.241 1.00 32.82  ? 853  THR   C CG2   1 
ATOM   5144 N N     . SER   A 1 854  ? 197.273 111.381 121.740 1.00 27.24  ? 854  SER   C N     1 
ATOM   5145 C CA    . SER   A 1 854  ? 196.959 110.511 120.612 1.00 25.04  ? 854  SER   C CA    1 
ATOM   5146 C C     . SER   A 1 854  ? 197.698 110.951 119.361 1.00 25.09  ? 854  SER   C C     1 
ATOM   5147 O O     . SER   A 1 854  ? 197.382 111.978 118.760 1.00 23.64  ? 854  SER   C O     1 
ATOM   5148 C CB    . SER   A 1 854  ? 195.468 110.497 120.338 1.00 21.33  ? 854  SER   C CB    1 
ATOM   5149 O OG    . SER   A 1 854  ? 195.172 109.682 119.240 1.00 22.40  ? 854  SER   C OG    1 
ATOM   5150 N N     . HIS   A 1 855  ? 198.678 110.158 118.952 1.00 26.62  ? 855  HIS   C N     1 
ATOM   5151 C CA    . HIS   A 1 855  ? 199.510 110.496 117.808 1.00 27.64  ? 855  HIS   C CA    1 
ATOM   5152 C C     . HIS   A 1 855  ? 198.816 110.182 116.488 1.00 28.80  ? 855  HIS   C C     1 
ATOM   5153 O O     . HIS   A 1 855  ? 199.249 110.632 115.426 1.00 28.42  ? 855  HIS   C O     1 
ATOM   5154 C CB    . HIS   A 1 855  ? 200.820 109.716 117.878 1.00 30.77  ? 855  HIS   C CB    1 
ATOM   5155 C CG    . HIS   A 1 855  ? 200.601 108.250 117.776 1.00 32.95  ? 855  HIS   C CG    1 
ATOM   5156 N ND1   . HIS   A 1 855  ? 199.996 107.521 118.778 1.00 34.23  ? 855  HIS   C ND1   1 
ATOM   5157 C CD2   . HIS   A 1 855  ? 200.894 107.369 116.793 1.00 34.05  ? 855  HIS   C CD2   1 
ATOM   5158 C CE1   . HIS   A 1 855  ? 199.927 106.253 118.414 1.00 37.20  ? 855  HIS   C CE1   1 
ATOM   5159 N NE2   . HIS   A 1 855  ? 200.465 106.134 117.214 1.00 36.17  ? 855  HIS   C NE2   1 
ATOM   5160 N N     . SER   A 1 856  ? 197.745 109.398 116.557 1.00 25.82  ? 856  SER   C N     1 
ATOM   5161 C CA    . SER   A 1 856  ? 197.045 108.961 115.357 1.00 20.87  ? 856  SER   C CA    1 
ATOM   5162 C C     . SER   A 1 856  ? 195.906 109.887 114.944 1.00 15.98  ? 856  SER   C C     1 
ATOM   5163 O O     . SER   A 1 856  ? 195.517 109.899 113.779 1.00 16.54  ? 856  SER   C O     1 
ATOM   5164 C CB    . SER   A 1 856  ? 196.504 107.559 115.558 1.00 23.25  ? 856  SER   C CB    1 
ATOM   5165 O OG    . SER   A 1 856  ? 197.547 106.634 115.724 1.00 26.82  ? 856  SER   C OG    1 
ATOM   5166 N N     . LEU   A 1 857  ? 195.367 110.664 115.882 1.00 16.26  ? 857  LEU   C N     1 
ATOM   5167 C CA    . LEU   A 1 857  ? 194.231 111.522 115.556 1.00 12.07  ? 857  LEU   C CA    1 
ATOM   5168 C C     . LEU   A 1 857  ? 194.723 112.805 114.906 1.00 12.64  ? 857  LEU   C C     1 
ATOM   5169 O O     . LEU   A 1 857  ? 195.383 113.621 115.550 1.00 16.08  ? 857  LEU   C O     1 
ATOM   5170 C CB    . LEU   A 1 857  ? 193.428 111.857 116.826 1.00 11.71  ? 857  LEU   C CB    1 
ATOM   5171 C CG    . LEU   A 1 857  ? 192.168 112.744 116.640 1.00 8.32   ? 857  LEU   C CG    1 
ATOM   5172 C CD1   . LEU   A 1 857  ? 191.121 111.995 115.829 1.00 8.75   ? 857  LEU   C CD1   1 
ATOM   5173 C CD2   . LEU   A 1 857  ? 191.613 113.126 117.997 1.00 10.36  ? 857  LEU   C CD2   1 
ATOM   5174 N N     . THR   A 1 858  ? 194.410 112.972 113.620 1.00 10.58  ? 858  THR   C N     1 
ATOM   5175 C CA    . THR   A 1 858  ? 194.917 114.103 112.851 1.00 9.36   ? 858  THR   C CA    1 
ATOM   5176 C C     . THR   A 1 858  ? 193.821 115.045 112.347 1.00 7.49   ? 858  THR   C C     1 
ATOM   5177 O O     . THR   A 1 858  ? 194.101 116.188 111.979 1.00 12.28  ? 858  THR   C O     1 
ATOM   5178 C CB    . THR   A 1 858  ? 195.771 113.605 111.673 1.00 10.89  ? 858  THR   C CB    1 
ATOM   5179 O OG1   . THR   A 1 858  ? 194.983 112.763 110.828 1.00 12.10  ? 858  THR   C OG1   1 
ATOM   5180 C CG2   . THR   A 1 858  ? 196.958 112.819 112.194 1.00 15.02  ? 858  THR   C CG2   1 
ATOM   5181 N N     . ARG   A 1 859  ? 192.577 114.585 112.336 1.00 8.78   ? 859  ARG   C N     1 
ATOM   5182 C CA    . ARG   A 1 859  ? 191.472 115.427 111.888 1.00 0.23   ? 859  ARG   C CA    1 
ATOM   5183 C C     . ARG   A 1 859  ? 190.398 115.488 112.961 1.00 0.01   ? 859  ARG   C C     1 
ATOM   5184 O O     . ARG   A 1 859  ? 189.827 114.459 113.327 1.00 0.00   ? 859  ARG   C O     1 
ATOM   5185 C CB    . ARG   A 1 859  ? 190.834 114.893 110.614 1.00 9.25   ? 859  ARG   C CB    1 
ATOM   5186 C CG    . ARG   A 1 859  ? 191.618 115.042 109.320 1.00 9.94   ? 859  ARG   C CG    1 
ATOM   5187 C CD    . ARG   A 1 859  ? 192.460 113.863 109.066 1.00 10.65  ? 859  ARG   C CD    1 
ATOM   5188 N NE    . ARG   A 1 859  ? 192.861 113.745 107.665 1.00 14.36  ? 859  ARG   C NE    1 
ATOM   5189 C CZ    . ARG   A 1 859  ? 193.994 114.253 107.137 1.00 18.27  ? 859  ARG   C CZ    1 
ATOM   5190 N NH1   . ARG   A 1 859  ? 194.827 114.927 107.890 1.00 18.40  ? 859  ARG   C NH1   1 
ATOM   5191 N NH2   . ARG   A 1 859  ? 194.268 114.068 105.857 1.00 27.86  ? 859  ARG   C NH2   1 
ATOM   5192 N N     . LEU   A 1 860  ? 190.125 116.679 113.475 1.00 0.00   ? 860  LEU   C N     1 
ATOM   5193 C CA    . LEU   A 1 860  ? 189.125 116.814 114.527 1.00 0.01   ? 860  LEU   C CA    1 
ATOM   5194 C C     . LEU   A 1 860  ? 188.117 117.907 114.211 1.00 0.00   ? 860  LEU   C C     1 
ATOM   5195 O O     . LEU   A 1 860  ? 188.481 119.076 114.063 1.00 0.00   ? 860  LEU   C O     1 
ATOM   5196 C CB    . LEU   A 1 860  ? 189.810 117.111 115.867 1.00 0.00   ? 860  LEU   C CB    1 
ATOM   5197 C CG    . LEU   A 1 860  ? 188.876 117.375 117.058 1.00 0.00   ? 860  LEU   C CG    1 
ATOM   5198 C CD1   . LEU   A 1 860  ? 188.069 116.112 117.381 1.00 0.00   ? 860  LEU   C CD1   1 
ATOM   5199 C CD2   . LEU   A 1 860  ? 189.697 117.804 118.256 1.00 0.05   ? 860  LEU   C CD2   1 
ATOM   5200 N N     . TYR   A 1 861  ? 186.846 117.532 114.129 1.00 0.01   ? 861  TYR   C N     1 
ATOM   5201 C CA    . TYR   A 1 861  ? 185.799 118.497 113.830 1.00 0.00   ? 861  TYR   C CA    1 
ATOM   5202 C C     . TYR   A 1 861  ? 184.841 118.645 115.005 1.00 0.00   ? 861  TYR   C C     1 
ATOM   5203 O O     . TYR   A 1 861  ? 184.085 117.726 115.317 1.00 0.00   ? 861  TYR   C O     1 
ATOM   5204 C CB    . TYR   A 1 861  ? 185.047 118.068 112.577 1.00 0.02   ? 861  TYR   C CB    1 
ATOM   5205 C CG    . TYR   A 1 861  ? 185.931 117.944 111.364 1.00 0.03   ? 861  TYR   C CG    1 
ATOM   5206 C CD1   . TYR   A 1 861  ? 186.565 116.749 111.102 1.00 1.18   ? 861  TYR   C CD1   1 
ATOM   5207 C CD2   . TYR   A 1 861  ? 186.112 119.016 110.520 1.00 0.12   ? 861  TYR   C CD2   1 
ATOM   5208 C CE1   . TYR   A 1 861  ? 187.372 116.624 109.999 1.00 0.04   ? 861  TYR   C CE1   1 
ATOM   5209 C CE2   . TYR   A 1 861  ? 186.926 118.891 109.413 1.00 0.15   ? 861  TYR   C CE2   1 
ATOM   5210 C CZ    . TYR   A 1 861  ? 187.556 117.697 109.158 1.00 0.90   ? 861  TYR   C CZ    1 
ATOM   5211 O OH    . TYR   A 1 861  ? 188.366 117.567 108.060 1.00 10.35  ? 861  TYR   C OH    1 
ATOM   5212 N N     . VAL   A 1 862  ? 184.885 119.797 115.670 1.00 0.01   ? 862  VAL   C N     1 
ATOM   5213 C CA    . VAL   A 1 862  ? 184.071 120.030 116.863 1.00 0.01   ? 862  VAL   C CA    1 
ATOM   5214 C C     . VAL   A 1 862  ? 183.187 121.263 116.759 1.00 0.02   ? 862  VAL   C C     1 
ATOM   5215 O O     . VAL   A 1 862  ? 182.794 121.837 117.774 1.00 0.12   ? 862  VAL   C O     1 
ATOM   5216 C CB    . VAL   A 1 862  ? 184.962 120.158 118.106 1.00 0.02   ? 862  VAL   C CB    1 
ATOM   5217 C CG1   . VAL   A 1 862  ? 185.625 118.849 118.392 1.00 0.00   ? 862  VAL   C CG1   1 
ATOM   5218 C CG2   . VAL   A 1 862  ? 186.005 121.236 117.877 1.00 0.02   ? 862  VAL   C CG2   1 
ATOM   5219 N N     . GLY   A 1 863  ? 182.871 121.672 115.545 1.00 0.09   ? 863  GLY   C N     1 
ATOM   5220 C CA    . GLY   A 1 863  ? 182.044 122.852 115.357 1.00 0.13   ? 863  GLY   C CA    1 
ATOM   5221 C C     . GLY   A 1 863  ? 180.591 122.573 115.705 1.00 0.05   ? 863  GLY   C C     1 
ATOM   5222 O O     . GLY   A 1 863  ? 180.224 121.441 116.016 1.00 0.00   ? 863  GLY   C O     1 
ATOM   5223 N N     . GLU   A 1 864  ? 179.776 123.620 115.658 1.00 0.14   ? 864  GLU   C N     1 
ATOM   5224 C CA    . GLU   A 1 864  ? 178.361 123.559 116.008 1.00 0.01   ? 864  GLU   C CA    1 
ATOM   5225 C C     . GLU   A 1 864  ? 178.131 123.078 117.443 1.00 7.46   ? 864  GLU   C C     1 
ATOM   5226 O O     . GLU   A 1 864  ? 177.182 122.349 117.721 1.00 7.66   ? 864  GLU   C O     1 
ATOM   5227 C CB    . GLU   A 1 864  ? 177.609 122.660 115.031 1.00 2.87   ? 864  GLU   C CB    1 
ATOM   5228 C CG    . GLU   A 1 864  ? 177.768 123.037 113.566 1.00 0.58   ? 864  GLU   C CG    1 
ATOM   5229 C CD    . GLU   A 1 864  ? 177.153 124.354 113.229 1.00 8.49   ? 864  GLU   C CD    1 
ATOM   5230 O OE1   . GLU   A 1 864  ? 176.395 124.850 114.024 1.00 12.64  ? 864  GLU   C OE1   1 
ATOM   5231 O OE2   . GLU   A 1 864  ? 177.434 124.868 112.172 1.00 16.26  ? 864  GLU   C OE2   1 
ATOM   5232 N N     . ASN   A 1 865  ? 178.988 123.518 118.354 1.00 7.50   ? 865  ASN   C N     1 
ATOM   5233 C CA    . ASN   A 1 865  ? 178.868 123.208 119.773 1.00 0.52   ? 865  ASN   C CA    1 
ATOM   5234 C C     . ASN   A 1 865  ? 179.035 124.501 120.562 1.00 8.09   ? 865  ASN   C C     1 
ATOM   5235 O O     . ASN   A 1 865  ? 179.230 125.561 119.976 1.00 10.06  ? 865  ASN   C O     1 
ATOM   5236 C CB    . ASN   A 1 865  ? 179.894 122.176 120.200 1.00 10.90  ? 865  ASN   C CB    1 
ATOM   5237 C CG    . ASN   A 1 865  ? 179.634 120.792 119.655 1.00 0.10   ? 865  ASN   C CG    1 
ATOM   5238 O OD1   . ASN   A 1 865  ? 178.646 120.127 120.012 1.00 9.13   ? 865  ASN   C OD1   1 
ATOM   5239 N ND2   . ASN   A 1 865  ? 180.521 120.335 118.812 1.00 7.28   ? 865  ASN   C ND2   1 
ATOM   5240 N N     . ALA   A 1 866  ? 178.965 124.434 121.884 1.00 9.06   ? 866  ALA   C N     1 
ATOM   5241 C CA    . ALA   A 1 866  ? 179.116 125.637 122.697 1.00 7.72   ? 866  ALA   C CA    1 
ATOM   5242 C C     . ALA   A 1 866  ? 180.525 125.742 123.269 1.00 10.37  ? 866  ALA   C C     1 
ATOM   5243 O O     . ALA   A 1 866  ? 180.713 126.155 124.416 1.00 14.49  ? 866  ALA   C O     1 
ATOM   5244 C CB    . ALA   A 1 866  ? 178.093 125.643 123.822 1.00 10.63  ? 866  ALA   C CB    1 
ATOM   5245 N N     . LEU   A 1 867  ? 181.523 125.389 122.467 1.00 9.95   ? 867  LEU   C N     1 
ATOM   5246 C CA    . LEU   A 1 867  ? 182.904 125.441 122.927 1.00 9.78   ? 867  LEU   C CA    1 
ATOM   5247 C C     . LEU   A 1 867  ? 183.430 126.853 122.763 1.00 11.76  ? 867  LEU   C C     1 
ATOM   5248 O O     . LEU   A 1 867  ? 184.248 127.122 121.884 1.00 18.57  ? 867  LEU   C O     1 
ATOM   5249 C CB    . LEU   A 1 867  ? 183.790 124.476 122.123 1.00 7.77   ? 867  LEU   C CB    1 
ATOM   5250 C CG    . LEU   A 1 867  ? 183.332 123.019 122.057 1.00 7.61   ? 867  LEU   C CG    1 
ATOM   5251 C CD1   . LEU   A 1 867  ? 184.367 122.212 121.302 1.00 7.44   ? 867  LEU   C CD1   1 
ATOM   5252 C CD2   . LEU   A 1 867  ? 183.117 122.479 123.444 1.00 14.28  ? 867  LEU   C CD2   1 
ATOM   5253 N N     . GLY   A 1 868  ? 182.955 127.750 123.617 1.00 9.76   ? 868  GLY   C N     1 
ATOM   5254 C CA    . GLY   A 1 868  ? 183.243 129.172 123.480 1.00 13.13  ? 868  GLY   C CA    1 
ATOM   5255 C C     . GLY   A 1 868  ? 184.709 129.483 123.743 1.00 18.37  ? 868  GLY   C C     1 
ATOM   5256 O O     . GLY   A 1 868  ? 185.546 128.582 123.818 1.00 19.65  ? 868  GLY   C O     1 
ATOM   5257 N N     . ASP   A 1 869  ? 185.028 130.765 123.876 1.00 18.52  ? 869  ASP   C N     1 
ATOM   5258 C CA    . ASP   A 1 869  ? 186.415 131.200 123.984 1.00 16.80  ? 869  ASP   C CA    1 
ATOM   5259 C C     . ASP   A 1 869  ? 187.152 130.614 125.183 1.00 21.07  ? 869  ASP   C C     1 
ATOM   5260 O O     . ASP   A 1 869  ? 188.363 130.389 125.123 1.00 24.26  ? 869  ASP   C O     1 
ATOM   5261 C CB    . ASP   A 1 869  ? 186.452 132.719 124.049 1.00 19.65  ? 869  ASP   C CB    1 
ATOM   5262 C CG    . ASP   A 1 869  ? 185.505 133.234 125.088 1.00 31.48  ? 869  ASP   C CG    1 
ATOM   5263 O OD1   . ASP   A 1 869  ? 184.368 132.810 125.060 1.00 29.70  ? 869  ASP   C OD1   1 
ATOM   5264 O OD2   . ASP   A 1 869  ? 185.899 134.024 125.906 1.00 37.55  ? 869  ASP   C OD2   1 
ATOM   5265 N N     . SER   A 1 870  ? 186.425 130.329 126.258 1.00 20.59  ? 870  SER   C N     1 
ATOM   5266 C CA    . SER   A 1 870  ? 187.032 129.751 127.448 1.00 19.55  ? 870  SER   C CA    1 
ATOM   5267 C C     . SER   A 1 870  ? 187.338 128.271 127.247 1.00 20.78  ? 870  SER   C C     1 
ATOM   5268 O O     . SER   A 1 870  ? 188.060 127.664 128.037 1.00 24.25  ? 870  SER   C O     1 
ATOM   5269 C CB    . SER   A 1 870  ? 186.113 129.927 128.640 1.00 22.00  ? 870  SER   C CB    1 
ATOM   5270 O OG    . SER   A 1 870  ? 184.954 129.152 128.498 1.00 23.51  ? 870  SER   C OG    1 
ATOM   5271 N N     . GLY   A 1 871  ? 186.770 127.692 126.193 1.00 20.46  ? 871  GLY   C N     1 
ATOM   5272 C CA    . GLY   A 1 871  ? 186.942 126.281 125.886 1.00 19.75  ? 871  GLY   C CA    1 
ATOM   5273 C C     . GLY   A 1 871  ? 188.023 126.075 124.833 1.00 19.69  ? 871  GLY   C C     1 
ATOM   5274 O O     . GLY   A 1 871  ? 188.892 125.213 124.977 1.00 22.72  ? 871  GLY   C O     1 
ATOM   5275 N N     . VAL   A 1 872  ? 187.984 126.885 123.780 1.00 19.20  ? 872  VAL   C N     1 
ATOM   5276 C CA    . VAL   A 1 872  ? 188.948 126.750 122.698 1.00 19.54  ? 872  VAL   C CA    1 
ATOM   5277 C C     . VAL   A 1 872  ? 190.354 126.994 123.214 1.00 24.16  ? 872  VAL   C C     1 
ATOM   5278 O O     . VAL   A 1 872  ? 191.314 126.403 122.724 1.00 26.98  ? 872  VAL   C O     1 
ATOM   5279 C CB    . VAL   A 1 872  ? 188.632 127.728 121.553 1.00 18.21  ? 872  VAL   C CB    1 
ATOM   5280 C CG1   . VAL   A 1 872  ? 189.005 129.137 121.933 1.00 24.58  ? 872  VAL   C CG1   1 
ATOM   5281 C CG2   . VAL   A 1 872  ? 189.375 127.323 120.312 1.00 17.93  ? 872  VAL   C CG2   1 
ATOM   5282 N N     . ALA   A 1 873  ? 190.474 127.848 124.229 1.00 23.03  ? 873  ALA   C N     1 
ATOM   5283 C CA    . ALA   A 1 873  ? 191.763 128.143 124.828 1.00 22.14  ? 873  ALA   C CA    1 
ATOM   5284 C C     . ALA   A 1 873  ? 192.426 126.879 125.366 1.00 25.66  ? 873  ALA   C C     1 
ATOM   5285 O O     . ALA   A 1 873  ? 193.652 126.764 125.346 1.00 28.58  ? 873  ALA   C O     1 
ATOM   5286 C CB    . ALA   A 1 873  ? 191.591 129.161 125.939 1.00 21.91  ? 873  ALA   C CB    1 
ATOM   5287 N N     . ILE   A 1 874  ? 191.623 125.936 125.858 1.00 24.18  ? 874  ILE   C N     1 
ATOM   5288 C CA    . ILE   A 1 874  ? 192.148 124.694 126.407 1.00 22.22  ? 874  ILE   C CA    1 
ATOM   5289 C C     . ILE   A 1 874  ? 192.653 123.805 125.281 1.00 25.20  ? 874  ILE   C C     1 
ATOM   5290 O O     . ILE   A 1 874  ? 193.746 123.237 125.359 1.00 29.20  ? 874  ILE   C O     1 
ATOM   5291 C CB    . ILE   A 1 874  ? 191.071 123.963 127.222 1.00 17.73  ? 874  ILE   C CB    1 
ATOM   5292 C CG1   . ILE   A 1 874  ? 190.714 124.787 128.453 1.00 20.09  ? 874  ILE   C CG1   1 
ATOM   5293 C CG2   . ILE   A 1 874  ? 191.546 122.579 127.615 1.00 20.28  ? 874  ILE   C CG2   1 
ATOM   5294 C CD1   . ILE   A 1 874  ? 189.465 124.311 129.157 1.00 24.53  ? 874  ILE   C CD1   1 
ATOM   5295 N N     . LEU   A 1 875  ? 191.860 123.705 124.219 1.00 24.15  ? 875  LEU   C N     1 
ATOM   5296 C CA    . LEU   A 1 875  ? 192.257 122.917 123.062 1.00 21.21  ? 875  LEU   C CA    1 
ATOM   5297 C C     . LEU   A 1 875  ? 193.516 123.501 122.442 1.00 27.38  ? 875  LEU   C C     1 
ATOM   5298 O O     . LEU   A 1 875  ? 194.402 122.764 122.010 1.00 29.35  ? 875  LEU   C O     1 
ATOM   5299 C CB    . LEU   A 1 875  ? 191.143 122.907 122.003 1.00 17.75  ? 875  LEU   C CB    1 
ATOM   5300 C CG    . LEU   A 1 875  ? 189.844 122.165 122.362 1.00 16.99  ? 875  LEU   C CG    1 
ATOM   5301 C CD1   . LEU   A 1 875  ? 188.797 122.442 121.290 1.00 15.54  ? 875  LEU   C CD1   1 
ATOM   5302 C CD2   . LEU   A 1 875  ? 190.112 120.680 122.463 1.00 19.77  ? 875  LEU   C CD2   1 
ATOM   5303 N N     . CYS   A 1 876  ? 193.595 124.832 122.404 1.00 28.62  ? 876  CYS   C N     1 
ATOM   5304 C CA    . CYS   A 1 876  ? 194.739 125.513 121.817 1.00 30.67  ? 876  CYS   C CA    1 
ATOM   5305 C C     . CYS   A 1 876  ? 196.005 125.287 122.626 1.00 32.23  ? 876  CYS   C C     1 
ATOM   5306 O O     . CYS   A 1 876  ? 197.071 125.045 122.061 1.00 36.96  ? 876  CYS   C O     1 
ATOM   5307 C CB    . CYS   A 1 876  ? 194.481 127.011 121.702 1.00 29.35  ? 876  CYS   C CB    1 
ATOM   5308 S SG    . CYS   A 1 876  ? 193.241 127.449 120.468 1.00 33.36  ? 876  CYS   C SG    1 
ATOM   5309 N N     . GLU   A 1 877  ? 195.901 125.344 123.949 1.00 31.49  ? 877  GLU   C N     1 
ATOM   5310 C CA    . GLU   A 1 877  ? 197.080 125.161 124.785 1.00 34.00  ? 877  GLU   C CA    1 
ATOM   5311 C C     . GLU   A 1 877  ? 197.758 123.827 124.506 1.00 34.70  ? 877  GLU   C C     1 
ATOM   5312 O O     . GLU   A 1 877  ? 198.987 123.742 124.483 1.00 36.39  ? 877  GLU   C O     1 
ATOM   5313 C CB    . GLU   A 1 877  ? 196.711 125.254 126.267 1.00 35.26  ? 877  GLU   C CB    1 
ATOM   5314 C CG    . GLU   A 1 877  ? 197.887 125.065 127.231 1.00 39.96  ? 877  GLU   C CG    1 
ATOM   5315 C CD    . GLU   A 1 877  ? 198.931 126.149 127.129 1.00 49.88  ? 877  GLU   C CD    1 
ATOM   5316 O OE1   . GLU   A 1 877  ? 198.638 127.190 126.590 1.00 47.41  ? 877  GLU   C OE1   1 
ATOM   5317 O OE2   . GLU   A 1 877  ? 200.025 125.931 127.592 1.00 46.88  ? 877  GLU   C OE2   1 
ATOM   5318 N N     . LYS   A 1 878  ? 196.970 122.780 124.281 1.00 31.33  ? 878  LYS   C N     1 
ATOM   5319 C CA    . LYS   A 1 878  ? 197.566 121.483 123.998 1.00 30.35  ? 878  LYS   C CA    1 
ATOM   5320 C C     . LYS   A 1 878  ? 197.905 121.317 122.513 1.00 32.35  ? 878  LYS   C C     1 
ATOM   5321 O O     . LYS   A 1 878  ? 198.923 120.717 122.172 1.00 33.98  ? 878  LYS   C O     1 
ATOM   5322 C CB    . LYS   A 1 878  ? 196.646 120.357 124.468 1.00 30.63  ? 878  LYS   C CB    1 
ATOM   5323 C CG    . LYS   A 1 878  ? 196.374 120.327 125.991 1.00 31.60  ? 878  LYS   C CG    1 
ATOM   5324 C CD    . LYS   A 1 878  ? 197.646 120.185 126.817 1.00 36.21  ? 878  LYS   C CD    1 
ATOM   5325 C CE    . LYS   A 1 878  ? 197.324 120.028 128.299 1.00 35.22  ? 878  LYS   C CE    1 
ATOM   5326 N NZ    . LYS   A 1 878  ? 198.556 119.951 129.129 1.00 44.68  ? 878  LYS   C NZ    1 
ATOM   5327 N N     . ALA   A 1 879  ? 197.078 121.881 121.627 1.00 31.81  ? 879  ALA   C N     1 
ATOM   5328 C CA    . ALA   A 1 879  ? 197.319 121.797 120.185 1.00 32.28  ? 879  ALA   C CA    1 
ATOM   5329 C C     . ALA   A 1 879  ? 198.569 122.585 119.809 1.00 34.51  ? 879  ALA   C C     1 
ATOM   5330 O O     . ALA   A 1 879  ? 199.227 122.300 118.808 1.00 35.73  ? 879  ALA   C O     1 
ATOM   5331 C CB    . ALA   A 1 879  ? 196.117 122.312 119.411 1.00 30.04  ? 879  ALA   C CB    1 
ATOM   5332 N N     . LYS   A 1 880  ? 198.896 123.580 120.626 1.00 34.99  ? 880  LYS   C N     1 
ATOM   5333 C CA    . LYS   A 1 880  ? 200.087 124.399 120.457 1.00 34.00  ? 880  LYS   C CA    1 
ATOM   5334 C C     . LYS   A 1 880  ? 201.361 123.567 120.488 1.00 33.15  ? 880  LYS   C C     1 
ATOM   5335 O O     . LYS   A 1 880  ? 202.371 123.950 119.901 1.00 35.00  ? 880  LYS   C O     1 
ATOM   5336 C CB    . LYS   A 1 880  ? 200.142 125.471 121.544 1.00 36.22  ? 880  LYS   C CB    1 
ATOM   5337 C CG    . LYS   A 1 880  ? 201.338 126.406 121.463 1.00 39.57  ? 880  LYS   C CG    1 
ATOM   5338 C CD    . LYS   A 1 880  ? 201.241 127.520 122.502 1.00 41.77  ? 880  LYS   C CD    1 
ATOM   5339 C CE    . LYS   A 1 880  ? 201.529 127.010 123.913 1.00 42.47  ? 880  LYS   C CE    1 
ATOM   5340 N NZ    . LYS   A 1 880  ? 201.541 128.116 124.906 1.00 43.78  ? 880  LYS   C NZ    1 
ATOM   5341 N N     . ASN   A 1 881  ? 201.339 122.454 121.210 1.00 34.88  ? 881  ASN   C N     1 
ATOM   5342 C CA    . ASN   A 1 881  ? 202.522 121.620 121.342 1.00 37.26  ? 881  ASN   C CA    1 
ATOM   5343 C C     . ASN   A 1 881  ? 202.965 121.128 119.960 1.00 36.27  ? 881  ASN   C C     1 
ATOM   5344 O O     . ASN   A 1 881  ? 202.186 120.482 119.260 1.00 38.66  ? 881  ASN   C O     1 
ATOM   5345 C CB    . ASN   A 1 881  ? 202.243 120.447 122.270 1.00 40.85  ? 881  ASN   C CB    1 
ATOM   5346 C CG    . ASN   A 1 881  ? 203.475 119.649 122.616 1.00 43.30  ? 881  ASN   C CG    1 
ATOM   5347 O OD1   . ASN   A 1 881  ? 204.197 119.163 121.735 1.00 43.37  ? 881  ASN   C OD1   1 
ATOM   5348 N ND2   . ASN   A 1 881  ? 203.734 119.504 123.891 1.00 44.28  ? 881  ASN   C ND2   1 
ATOM   5349 N N     . PRO   A 1 882  ? 204.218 121.378 119.558 1.00 37.88  ? 882  PRO   C N     1 
ATOM   5350 C CA    . PRO   A 1 882  ? 204.772 121.097 118.243 1.00 39.38  ? 882  PRO   C CA    1 
ATOM   5351 C C     . PRO   A 1 882  ? 204.787 119.605 117.909 1.00 39.99  ? 882  PRO   C C     1 
ATOM   5352 O O     . PRO   A 1 882  ? 205.003 119.229 116.758 1.00 40.46  ? 882  PRO   C O     1 
ATOM   5353 C CB    . PRO   A 1 882  ? 206.192 121.671 118.349 1.00 38.56  ? 882  PRO   C CB    1 
ATOM   5354 C CG    . PRO   A 1 882  ? 206.506 121.670 119.828 1.00 40.98  ? 882  PRO   C CG    1 
ATOM   5355 C CD    . PRO   A 1 882  ? 205.188 121.957 120.506 1.00 39.35  ? 882  PRO   C CD    1 
ATOM   5356 N N     . GLN   A 1 883  ? 204.572 118.758 118.914 1.00 39.75  ? 883  GLN   C N     1 
ATOM   5357 C CA    . GLN   A 1 883  ? 204.563 117.316 118.705 1.00 41.94  ? 883  GLN   C CA    1 
ATOM   5358 C C     . GLN   A 1 883  ? 203.152 116.786 118.455 1.00 38.88  ? 883  GLN   C C     1 
ATOM   5359 O O     . GLN   A 1 883  ? 202.960 115.585 118.266 1.00 36.98  ? 883  GLN   C O     1 
ATOM   5360 C CB    . GLN   A 1 883  ? 205.185 116.601 119.906 1.00 44.95  ? 883  GLN   C CB    1 
ATOM   5361 C CG    . GLN   A 1 883  ? 206.623 117.002 120.179 1.00 48.68  ? 883  GLN   C CG    1 
ATOM   5362 C CD    . GLN   A 1 883  ? 207.535 116.713 119.008 1.00 52.82  ? 883  GLN   C CD    1 
ATOM   5363 O OE1   . GLN   A 1 883  ? 207.591 115.585 118.510 1.00 49.59  ? 883  GLN   C OE1   1 
ATOM   5364 N NE2   . GLN   A 1 883  ? 208.253 117.732 118.555 1.00 49.50  ? 883  GLN   C NE2   1 
ATOM   5365 N N     . CYS   A 1 884  ? 202.165 117.678 118.459 1.00 35.53  ? 884  CYS   C N     1 
ATOM   5366 C CA    . CYS   A 1 884  ? 200.790 117.294 118.170 1.00 31.13  ? 884  CYS   C CA    1 
ATOM   5367 C C     . CYS   A 1 884  ? 200.641 117.122 116.661 1.00 31.63  ? 884  CYS   C C     1 
ATOM   5368 O O     . CYS   A 1 884  ? 201.119 117.957 115.895 1.00 32.28  ? 884  CYS   C O     1 
ATOM   5369 C CB    . CYS   A 1 884  ? 199.810 118.349 118.684 1.00 29.05  ? 884  CYS   C CB    1 
ATOM   5370 S SG    . CYS   A 1 884  ? 198.067 117.917 118.467 1.00 33.35  ? 884  CYS   C SG    1 
ATOM   5371 N N     . ASN   A 1 885  ? 200.006 116.034 116.232 1.00 27.61  ? 885  ASN   C N     1 
ATOM   5372 C CA    . ASN   A 1 885  ? 199.915 115.728 114.805 1.00 23.61  ? 885  ASN   C CA    1 
ATOM   5373 C C     . ASN   A 1 885  ? 198.655 116.266 114.140 1.00 20.22  ? 885  ASN   C C     1 
ATOM   5374 O O     . ASN   A 1 885  ? 198.389 115.969 112.978 1.00 19.25  ? 885  ASN   C O     1 
ATOM   5375 C CB    . ASN   A 1 885  ? 200.030 114.236 114.572 1.00 21.12  ? 885  ASN   C CB    1 
ATOM   5376 C CG    . ASN   A 1 885  ? 201.412 113.724 114.835 1.00 28.56  ? 885  ASN   C CG    1 
ATOM   5377 O OD1   . ASN   A 1 885  ? 202.399 114.461 114.722 1.00 32.25  ? 885  ASN   C OD1   1 
ATOM   5378 N ND2   . ASN   A 1 885  ? 201.509 112.469 115.176 1.00 28.83  ? 885  ASN   C ND2   1 
ATOM   5379 N N     . LEU   A 1 886  ? 197.894 117.072 114.862 1.00 17.93  ? 886  LEU   C N     1 
ATOM   5380 C CA    . LEU   A 1 886  ? 196.661 117.632 114.327 1.00 11.89  ? 886  LEU   C CA    1 
ATOM   5381 C C     . LEU   A 1 886  ? 196.919 118.408 113.040 1.00 12.22  ? 886  LEU   C C     1 
ATOM   5382 O O     . LEU   A 1 886  ? 197.751 119.313 113.011 1.00 16.73  ? 886  LEU   C O     1 
ATOM   5383 C CB    . LEU   A 1 886  ? 196.038 118.558 115.380 1.00 10.90  ? 886  LEU   C CB    1 
ATOM   5384 C CG    . LEU   A 1 886  ? 194.714 119.239 115.032 1.00 6.38   ? 886  LEU   C CG    1 
ATOM   5385 C CD1   . LEU   A 1 886  ? 193.609 118.201 114.921 1.00 5.13   ? 886  LEU   C CD1   1 
ATOM   5386 C CD2   . LEU   A 1 886  ? 194.395 120.257 116.117 1.00 7.57   ? 886  LEU   C CD2   1 
ATOM   5387 N N     . GLN   A 1 887  ? 196.191 118.053 111.979 1.00 10.84  ? 887  GLN   C N     1 
ATOM   5388 C CA    . GLN   A 1 887  ? 196.341 118.713 110.685 1.00 9.10   ? 887  GLN   C CA    1 
ATOM   5389 C C     . GLN   A 1 887  ? 195.135 119.565 110.313 1.00 7.19   ? 887  GLN   C C     1 
ATOM   5390 O O     . GLN   A 1 887  ? 195.288 120.627 109.704 1.00 2.50   ? 887  GLN   C O     1 
ATOM   5391 C CB    . GLN   A 1 887  ? 196.596 117.692 109.582 1.00 9.46   ? 887  GLN   C CB    1 
ATOM   5392 C CG    . GLN   A 1 887  ? 197.911 116.976 109.718 1.00 12.34  ? 887  GLN   C CG    1 
ATOM   5393 C CD    . GLN   A 1 887  ? 198.223 116.085 108.534 1.00 14.05  ? 887  GLN   C CD    1 
ATOM   5394 O OE1   . GLN   A 1 887  ? 197.375 115.852 107.664 1.00 16.21  ? 887  GLN   C OE1   1 
ATOM   5395 N NE2   . GLN   A 1 887  ? 199.448 115.575 108.490 1.00 16.32  ? 887  GLN   C NE2   1 
ATOM   5396 N N     . LYS   A 1 888  ? 193.940 119.109 110.669 1.00 5.84   ? 888  LYS   C N     1 
ATOM   5397 C CA    . LYS   A 1 888  ? 192.734 119.852 110.324 1.00 2.62   ? 888  LYS   C CA    1 
ATOM   5398 C C     . LYS   A 1 888  ? 191.880 120.104 111.554 1.00 0.18   ? 888  LYS   C C     1 
ATOM   5399 O O     . LYS   A 1 888  ? 191.546 119.169 112.283 1.00 0.00   ? 888  LYS   C O     1 
ATOM   5400 C CB    . LYS   A 1 888  ? 191.909 119.087 109.296 1.00 10.93  ? 888  LYS   C CB    1 
ATOM   5401 C CG    . LYS   A 1 888  ? 192.641 118.750 108.010 1.00 9.85   ? 888  LYS   C CG    1 
ATOM   5402 C CD    . LYS   A 1 888  ? 191.679 118.221 106.968 1.00 12.36  ? 888  LYS   C CD    1 
ATOM   5403 C CE    . LYS   A 1 888  ? 192.385 117.894 105.665 1.00 16.42  ? 888  LYS   C CE    1 
ATOM   5404 N NZ    . LYS   A 1 888  ? 191.440 117.372 104.644 1.00 22.80  ? 888  LYS   C NZ    1 
ATOM   5405 N N     . LEU   A 1 889  ? 191.512 121.360 111.783 1.00 0.30   ? 889  LEU   C N     1 
ATOM   5406 C CA    . LEU   A 1 889  ? 190.703 121.684 112.952 1.00 0.06   ? 889  LEU   C CA    1 
ATOM   5407 C C     . LEU   A 1 889  ? 189.452 122.482 112.582 1.00 0.03   ? 889  LEU   C C     1 
ATOM   5408 O O     . LEU   A 1 889  ? 189.537 123.614 112.096 1.00 2.67   ? 889  LEU   C O     1 
ATOM   5409 C CB    . LEU   A 1 889  ? 191.571 122.445 113.957 1.00 0.05   ? 889  LEU   C CB    1 
ATOM   5410 C CG    . LEU   A 1 889  ? 190.903 122.896 115.244 1.00 0.01   ? 889  LEU   C CG    1 
ATOM   5411 C CD1   . LEU   A 1 889  ? 190.391 121.679 116.036 1.00 0.00   ? 889  LEU   C CD1   1 
ATOM   5412 C CD2   . LEU   A 1 889  ? 191.914 123.679 116.068 1.00 0.01   ? 889  LEU   C CD2   1 
ATOM   5413 N N     . GLY   A 1 890  ? 188.290 121.880 112.818 1.00 0.06   ? 890  GLY   C N     1 
ATOM   5414 C CA    . GLY   A 1 890  ? 187.008 122.461 112.424 1.00 0.01   ? 890  GLY   C CA    1 
ATOM   5415 C C     . GLY   A 1 890  ? 186.288 123.251 113.520 1.00 0.03   ? 890  GLY   C C     1 
ATOM   5416 O O     . GLY   A 1 890  ? 185.157 122.920 113.885 1.00 0.01   ? 890  GLY   C O     1 
ATOM   5417 N N     . LEU   A 1 891  ? 186.906 124.320 114.007 1.00 0.08   ? 891  LEU   C N     1 
ATOM   5418 C CA    . LEU   A 1 891  ? 186.253 125.190 114.990 1.00 0.07   ? 891  LEU   C CA    1 
ATOM   5419 C C     . LEU   A 1 891  ? 185.328 126.166 114.293 1.00 0.01   ? 891  LEU   C C     1 
ATOM   5420 O O     . LEU   A 1 891  ? 185.598 127.365 114.249 1.00 0.72   ? 891  LEU   C O     1 
ATOM   5421 C CB    . LEU   A 1 891  ? 187.292 125.991 115.774 1.00 0.11   ? 891  LEU   C CB    1 
ATOM   5422 C CG    . LEU   A 1 891  ? 188.190 125.218 116.705 1.00 0.16   ? 891  LEU   C CG    1 
ATOM   5423 C CD1   . LEU   A 1 891  ? 189.340 126.104 117.102 1.00 6.86   ? 891  LEU   C CD1   1 
ATOM   5424 C CD2   . LEU   A 1 891  ? 187.402 124.796 117.937 1.00 0.47   ? 891  LEU   C CD2   1 
ATOM   5425 N N     . VAL   A 1 892  ? 184.254 125.634 113.730 1.00 0.13   ? 892  VAL   C N     1 
ATOM   5426 C CA    . VAL   A 1 892  ? 183.399 126.388 112.826 1.00 0.02   ? 892  VAL   C CA    1 
ATOM   5427 C C     . VAL   A 1 892  ? 182.422 127.326 113.520 1.00 0.05   ? 892  VAL   C C     1 
ATOM   5428 O O     . VAL   A 1 892  ? 182.527 128.541 113.402 1.00 0.01   ? 892  VAL   C O     1 
ATOM   5429 C CB    . VAL   A 1 892  ? 182.613 125.391 111.953 1.00 0.11   ? 892  VAL   C CB    1 
ATOM   5430 C CG1   . VAL   A 1 892  ? 181.604 126.101 111.101 1.00 9.01   ? 892  VAL   C CG1   1 
ATOM   5431 C CG2   . VAL   A 1 892  ? 183.592 124.628 111.077 1.00 0.00   ? 892  VAL   C CG2   1 
ATOM   5432 N N     . ASN   A 1 893  ? 181.471 126.779 114.252 1.00 9.48   ? 893  ASN   C N     1 
ATOM   5433 C CA    . ASN   A 1 893  ? 180.418 127.609 114.827 1.00 8.23   ? 893  ASN   C CA    1 
ATOM   5434 C C     . ASN   A 1 893  ? 180.331 127.433 116.328 1.00 8.52   ? 893  ASN   C C     1 
ATOM   5435 O O     . ASN   A 1 893  ? 179.288 127.060 116.861 1.00 10.86  ? 893  ASN   C O     1 
ATOM   5436 C CB    . ASN   A 1 893  ? 179.088 127.294 114.177 1.00 8.89   ? 893  ASN   C CB    1 
ATOM   5437 C CG    . ASN   A 1 893  ? 178.012 128.244 114.574 1.00 9.88   ? 893  ASN   C CG    1 
ATOM   5438 O OD1   . ASN   A 1 893  ? 178.296 129.385 114.941 1.00 11.13  ? 893  ASN   C OD1   1 
ATOM   5439 N ND2   . ASN   A 1 893  ? 176.780 127.801 114.510 1.00 14.10  ? 893  ASN   C ND2   1 
ATOM   5440 N N     . SER   A 1 894  ? 181.440 127.695 117.002 1.00 7.64   ? 894  SER   C N     1 
ATOM   5441 C CA    . SER   A 1 894  ? 181.532 127.511 118.439 1.00 7.54   ? 894  SER   C CA    1 
ATOM   5442 C C     . SER   A 1 894  ? 181.195 128.784 119.200 1.00 10.13  ? 894  SER   C C     1 
ATOM   5443 O O     . SER   A 1 894  ? 181.195 128.801 120.430 1.00 14.80  ? 894  SER   C O     1 
ATOM   5444 C CB    . SER   A 1 894  ? 182.919 127.048 118.807 1.00 9.38   ? 894  SER   C CB    1 
ATOM   5445 O OG    . SER   A 1 894  ? 183.204 125.801 118.244 1.00 6.44   ? 894  SER   C OG    1 
ATOM   5446 N N     . GLY   A 1 895  ? 180.917 129.857 118.472 1.00 12.08  ? 895  GLY   C N     1 
ATOM   5447 C CA    . GLY   A 1 895  ? 180.618 131.128 119.111 1.00 13.40  ? 895  GLY   C CA    1 
ATOM   5448 C C     . GLY   A 1 895  ? 181.878 131.782 119.654 1.00 13.85  ? 895  GLY   C C     1 
ATOM   5449 O O     . GLY   A 1 895  ? 181.855 132.401 120.717 1.00 17.08  ? 895  GLY   C O     1 
ATOM   5450 N N     . LEU   A 1 896  ? 182.986 131.627 118.938 1.00 13.06  ? 896  LEU   C N     1 
ATOM   5451 C CA    . LEU   A 1 896  ? 184.244 132.198 119.384 1.00 13.32  ? 896  LEU   C CA    1 
ATOM   5452 C C     . LEU   A 1 896  ? 184.252 133.689 119.149 1.00 15.15  ? 896  LEU   C C     1 
ATOM   5453 O O     . LEU   A 1 896  ? 183.631 134.182 118.204 1.00 19.32  ? 896  LEU   C O     1 
ATOM   5454 C CB    . LEU   A 1 896  ? 185.423 131.579 118.629 1.00 12.56  ? 896  LEU   C CB    1 
ATOM   5455 C CG    . LEU   A 1 896  ? 185.597 130.074 118.761 1.00 12.78  ? 896  LEU   C CG    1 
ATOM   5456 C CD1   . LEU   A 1 896  ? 186.821 129.633 117.969 1.00 13.19  ? 896  LEU   C CD1   1 
ATOM   5457 C CD2   . LEU   A 1 896  ? 185.724 129.700 120.222 1.00 17.05  ? 896  LEU   C CD2   1 
ATOM   5458 N N     . THR   A 1 897  ? 184.974 134.406 119.997 1.00 15.65  ? 897  THR   C N     1 
ATOM   5459 C CA    . THR   A 1 897  ? 185.138 135.839 119.837 1.00 16.85  ? 897  THR   C CA    1 
ATOM   5460 C C     . THR   A 1 897  ? 186.610 136.189 119.730 1.00 21.80  ? 897  THR   C C     1 
ATOM   5461 O O     . THR   A 1 897  ? 187.478 135.337 119.933 1.00 25.49  ? 897  THR   C O     1 
ATOM   5462 C CB    . THR   A 1 897  ? 184.485 136.611 120.993 1.00 23.46  ? 897  THR   C CB    1 
ATOM   5463 O OG1   . THR   A 1 897  ? 185.164 136.310 122.212 1.00 29.69  ? 897  THR   C OG1   1 
ATOM   5464 C CG2   . THR   A 1 897  ? 183.027 136.217 121.119 1.00 22.62  ? 897  THR   C CG2   1 
ATOM   5465 N N     . SER   A 1 898  ? 186.891 137.446 119.411 1.00 21.31  ? 898  SER   C N     1 
ATOM   5466 C CA    . SER   A 1 898  ? 188.248 137.901 119.135 1.00 23.68  ? 898  SER   C CA    1 
ATOM   5467 C C     . SER   A 1 898  ? 189.213 137.661 120.282 1.00 28.10  ? 898  SER   C C     1 
ATOM   5468 O O     . SER   A 1 898  ? 190.417 137.522 120.069 1.00 32.67  ? 898  SER   C O     1 
ATOM   5469 C CB    . SER   A 1 898  ? 188.225 139.378 118.828 1.00 27.15  ? 898  SER   C CB    1 
ATOM   5470 O OG    . SER   A 1 898  ? 187.865 140.112 119.966 1.00 30.18  ? 898  SER   C OG    1 
ATOM   5471 N N     . VAL   A 1 899  ? 188.694 137.571 121.495 1.00 27.13  ? 899  VAL   C N     1 
ATOM   5472 C CA    . VAL   A 1 899  ? 189.535 137.382 122.667 1.00 26.58  ? 899  VAL   C CA    1 
ATOM   5473 C C     . VAL   A 1 899  ? 190.325 136.079 122.606 1.00 28.75  ? 899  VAL   C C     1 
ATOM   5474 O O     . VAL   A 1 899  ? 191.354 135.946 123.267 1.00 30.31  ? 899  VAL   C O     1 
ATOM   5475 C CB    . VAL   A 1 899  ? 188.677 137.408 123.947 1.00 26.81  ? 899  VAL   C CB    1 
ATOM   5476 C CG1   . VAL   A 1 899  ? 187.887 136.112 124.086 1.00 27.59  ? 899  VAL   C CG1   1 
ATOM   5477 C CG2   . VAL   A 1 899  ? 189.570 137.619 125.166 1.00 32.22  ? 899  VAL   C CG2   1 
ATOM   5478 N N     . CYS   A 1 900  ? 189.841 135.105 121.838 1.00 28.91  ? 900  CYS   C N     1 
ATOM   5479 C CA    . CYS   A 1 900  ? 190.514 133.815 121.764 1.00 28.70  ? 900  CYS   C CA    1 
ATOM   5480 C C     . CYS   A 1 900  ? 191.444 133.709 120.570 1.00 31.44  ? 900  CYS   C C     1 
ATOM   5481 O O     . CYS   A 1 900  ? 192.114 132.691 120.395 1.00 31.99  ? 900  CYS   C O     1 
ATOM   5482 C CB    . CYS   A 1 900  ? 189.515 132.683 121.641 1.00 24.70  ? 900  CYS   C CB    1 
ATOM   5483 S SG    . CYS   A 1 900  ? 188.802 132.557 120.006 1.00 29.71  ? 900  CYS   C SG    1 
ATOM   5484 N N     . CYS   A 1 901  ? 191.472 134.732 119.725 1.00 31.33  ? 901  CYS   C N     1 
ATOM   5485 C CA    . CYS   A 1 901  ? 192.264 134.641 118.511 1.00 28.03  ? 901  CYS   C CA    1 
ATOM   5486 C C     . CYS   A 1 901  ? 193.746 134.611 118.815 1.00 32.70  ? 901  CYS   C C     1 
ATOM   5487 O O     . CYS   A 1 901  ? 194.537 134.129 118.003 1.00 35.55  ? 901  CYS   C O     1 
ATOM   5488 C CB    . CYS   A 1 901  ? 191.954 135.785 117.563 1.00 29.77  ? 901  CYS   C CB    1 
ATOM   5489 S SG    . CYS   A 1 901  ? 190.349 135.650 116.800 1.00 33.47  ? 901  CYS   C SG    1 
ATOM   5490 N N     . SER   A 1 902  ? 194.125 135.095 119.992 1.00 32.79  ? 902  SER   C N     1 
ATOM   5491 C CA    . SER   A 1 902  ? 195.515 135.052 120.396 1.00 36.10  ? 902  SER   C CA    1 
ATOM   5492 C C     . SER   A 1 902  ? 195.934 133.613 120.699 1.00 38.33  ? 902  SER   C C     1 
ATOM   5493 O O     . SER   A 1 902  ? 197.113 133.268 120.599 1.00 38.20  ? 902  SER   C O     1 
ATOM   5494 C CB    . SER   A 1 902  ? 195.729 135.932 121.609 1.00 34.72  ? 902  SER   C CB    1 
ATOM   5495 O OG    . SER   A 1 902  ? 195.090 135.400 122.734 1.00 35.21  ? 902  SER   C OG    1 
ATOM   5496 N N     . ALA   A 1 903  ? 194.963 132.765 121.052 1.00 33.93  ? 903  ALA   C N     1 
ATOM   5497 C CA    . ALA   A 1 903  ? 195.253 131.365 121.321 1.00 32.80  ? 903  ALA   C CA    1 
ATOM   5498 C C     . ALA   A 1 903  ? 195.444 130.630 120.007 1.00 32.31  ? 903  ALA   C C     1 
ATOM   5499 O O     . ALA   A 1 903  ? 196.351 129.805 119.868 1.00 36.21  ? 903  ALA   C O     1 
ATOM   5500 C CB    . ALA   A 1 903  ? 194.129 130.735 122.128 1.00 34.18  ? 903  ALA   C CB    1 
ATOM   5501 N N     . LEU   A 1 904  ? 194.611 130.968 119.026 1.00 32.07  ? 904  LEU   C N     1 
ATOM   5502 C CA    . LEU   A 1 904  ? 194.720 130.376 117.702 1.00 30.21  ? 904  LEU   C CA    1 
ATOM   5503 C C     . LEU   A 1 904  ? 196.029 130.809 117.060 1.00 35.03  ? 904  LEU   C C     1 
ATOM   5504 O O     . LEU   A 1 904  ? 196.682 130.026 116.370 1.00 35.67  ? 904  LEU   C O     1 
ATOM   5505 C CB    . LEU   A 1 904  ? 193.529 130.793 116.825 1.00 23.95  ? 904  LEU   C CB    1 
ATOM   5506 C CG    . LEU   A 1 904  ? 192.150 130.219 117.231 1.00 22.86  ? 904  LEU   C CG    1 
ATOM   5507 C CD1   . LEU   A 1 904  ? 191.053 130.912 116.435 1.00 22.49  ? 904  LEU   C CD1   1 
ATOM   5508 C CD2   . LEU   A 1 904  ? 192.117 128.720 116.964 1.00 21.48  ? 904  LEU   C CD2   1 
ATOM   5509 N N     . SER   A 1 905  ? 196.424 132.056 117.319 1.00 32.40  ? 905  SER   C N     1 
ATOM   5510 C CA    . SER   A 1 905  ? 197.672 132.596 116.801 1.00 32.50  ? 905  SER   C CA    1 
ATOM   5511 C C     . SER   A 1 905  ? 198.865 131.803 117.312 1.00 35.60  ? 905  SER   C C     1 
ATOM   5512 O O     . SER   A 1 905  ? 199.753 131.439 116.536 1.00 37.98  ? 905  SER   C O     1 
ATOM   5513 C CB    . SER   A 1 905  ? 197.815 134.046 117.200 1.00 33.68  ? 905  SER   C CB    1 
ATOM   5514 O OG    . SER   A 1 905  ? 199.024 134.571 116.742 1.00 38.47  ? 905  SER   C OG    1 
ATOM   5515 N N     . SER   A 1 906  ? 198.872 131.504 118.613 1.00 35.66  ? 906  SER   C N     1 
ATOM   5516 C CA    . SER   A 1 906  ? 199.960 130.733 119.203 1.00 37.66  ? 906  SER   C CA    1 
ATOM   5517 C C     . SER   A 1 906  ? 200.069 129.353 118.567 1.00 37.14  ? 906  SER   C C     1 
ATOM   5518 O O     . SER   A 1 906  ? 201.176 128.874 118.296 1.00 38.24  ? 906  SER   C O     1 
ATOM   5519 C CB    . SER   A 1 906  ? 199.748 130.582 120.696 1.00 40.74  ? 906  SER   C CB    1 
ATOM   5520 O OG    . SER   A 1 906  ? 199.848 131.817 121.349 1.00 43.99  ? 906  SER   C OG    1 
ATOM   5521 N N     . VAL   A 1 907  ? 198.928 128.722 118.299 1.00 36.14  ? 907  VAL   C N     1 
ATOM   5522 C CA    . VAL   A 1 907  ? 198.931 127.408 117.671 1.00 35.19  ? 907  VAL   C CA    1 
ATOM   5523 C C     . VAL   A 1 907  ? 199.473 127.479 116.250 1.00 34.55  ? 907  VAL   C C     1 
ATOM   5524 O O     . VAL   A 1 907  ? 200.310 126.670 115.862 1.00 35.64  ? 907  VAL   C O     1 
ATOM   5525 C CB    . VAL   A 1 907  ? 197.519 126.793 117.642 1.00 32.64  ? 907  VAL   C CB    1 
ATOM   5526 C CG1   . VAL   A 1 907  ? 197.526 125.492 116.832 1.00 29.78  ? 907  VAL   C CG1   1 
ATOM   5527 C CG2   . VAL   A 1 907  ? 197.056 126.523 119.057 1.00 38.24  ? 907  VAL   C CG2   1 
ATOM   5528 N N     . LEU   A 1 908  ? 199.023 128.470 115.483 1.00 33.94  ? 908  LEU   C N     1 
ATOM   5529 C CA    . LEU   A 1 908  ? 199.485 128.615 114.105 1.00 32.21  ? 908  LEU   C CA    1 
ATOM   5530 C C     . LEU   A 1 908  ? 200.993 128.827 114.044 1.00 37.20  ? 908  LEU   C C     1 
ATOM   5531 O O     . LEU   A 1 908  ? 201.672 128.266 113.182 1.00 38.13  ? 908  LEU   C O     1 
ATOM   5532 C CB    . LEU   A 1 908  ? 198.784 129.812 113.449 1.00 30.09  ? 908  LEU   C CB    1 
ATOM   5533 C CG    . LEU   A 1 908  ? 197.294 129.638 113.127 1.00 24.76  ? 908  LEU   C CG    1 
ATOM   5534 C CD1   . LEU   A 1 908  ? 196.690 130.995 112.813 1.00 26.74  ? 908  LEU   C CD1   1 
ATOM   5535 C CD2   . LEU   A 1 908  ? 197.144 128.714 111.933 1.00 23.49  ? 908  LEU   C CD2   1 
ATOM   5536 N N     . SER   A 1 909  ? 201.513 129.622 114.970 1.00 37.19  ? 909  SER   C N     1 
ATOM   5537 C CA    . SER   A 1 909  ? 202.939 129.917 115.035 1.00 37.94  ? 909  SER   C CA    1 
ATOM   5538 C C     . SER   A 1 909  ? 203.791 128.698 115.399 1.00 36.98  ? 909  SER   C C     1 
ATOM   5539 O O     . SER   A 1 909  ? 204.831 128.456 114.786 1.00 40.62  ? 909  SER   C O     1 
ATOM   5540 C CB    . SER   A 1 909  ? 203.177 131.023 116.040 1.00 41.36  ? 909  SER   C CB    1 
ATOM   5541 O OG    . SER   A 1 909  ? 204.540 131.308 116.172 1.00 43.86  ? 909  SER   C OG    1 
ATOM   5542 N N     . THR   A 1 910  ? 203.361 127.944 116.412 1.00 37.35  ? 910  THR   C N     1 
ATOM   5543 C CA    . THR   A 1 910  ? 204.161 126.830 116.922 1.00 37.42  ? 910  THR   C CA    1 
ATOM   5544 C C     . THR   A 1 910  ? 203.900 125.490 116.229 1.00 37.21  ? 910  THR   C C     1 
ATOM   5545 O O     . THR   A 1 910  ? 204.838 124.735 115.962 1.00 37.91  ? 910  THR   C O     1 
ATOM   5546 C CB    . THR   A 1 910  ? 203.928 126.659 118.435 1.00 39.17  ? 910  THR   C CB    1 
ATOM   5547 O OG1   . THR   A 1 910  ? 204.265 127.879 119.106 1.00 39.98  ? 910  THR   C OG1   1 
ATOM   5548 C CG2   . THR   A 1 910  ? 204.793 125.529 118.985 1.00 39.25  ? 910  THR   C CG2   1 
ATOM   5549 N N     . ASN   A 1 911  ? 202.639 125.177 115.959 1.00 35.30  ? 911  ASN   C N     1 
ATOM   5550 C CA    . ASN   A 1 911  ? 202.288 123.885 115.387 1.00 32.36  ? 911  ASN   C CA    1 
ATOM   5551 C C     . ASN   A 1 911  ? 202.455 123.899 113.873 1.00 31.71  ? 911  ASN   C C     1 
ATOM   5552 O O     . ASN   A 1 911  ? 201.659 124.496 113.150 1.00 33.00  ? 911  ASN   C O     1 
ATOM   5553 C CB    . ASN   A 1 911  ? 200.872 123.498 115.781 1.00 29.31  ? 911  ASN   C CB    1 
ATOM   5554 C CG    . ASN   A 1 911  ? 200.490 122.129 115.316 1.00 26.72  ? 911  ASN   C CG    1 
ATOM   5555 O OD1   . ASN   A 1 911  ? 200.848 121.710 114.207 1.00 26.87  ? 911  ASN   C OD1   1 
ATOM   5556 N ND2   . ASN   A 1 911  ? 199.773 121.409 116.143 1.00 28.17  ? 911  ASN   C ND2   1 
ATOM   5557 N N     . GLN   A 1 912  ? 203.498 123.228 113.391 1.00 30.12  ? 912  GLN   C N     1 
ATOM   5558 C CA    . GLN   A 1 912  ? 203.825 123.240 111.970 1.00 32.76  ? 912  GLN   C CA    1 
ATOM   5559 C C     . GLN   A 1 912  ? 203.087 122.151 111.202 1.00 31.57  ? 912  GLN   C C     1 
ATOM   5560 O O     . GLN   A 1 912  ? 203.275 121.997 109.996 1.00 30.45  ? 912  GLN   C O     1 
ATOM   5561 C CB    . GLN   A 1 912  ? 205.335 123.082 111.767 1.00 35.67  ? 912  GLN   C CB    1 
ATOM   5562 C CG    . GLN   A 1 912  ? 206.159 124.240 112.309 1.00 40.40  ? 912  GLN   C CG    1 
ATOM   5563 C CD    . GLN   A 1 912  ? 207.649 124.049 112.079 1.00 47.61  ? 912  GLN   C CD    1 
ATOM   5564 O OE1   . GLN   A 1 912  ? 208.066 123.529 111.040 1.00 44.53  ? 912  GLN   C OE1   1 
ATOM   5565 N NE2   . GLN   A 1 912  ? 208.461 124.465 113.046 1.00 49.03  ? 912  GLN   C NE2   1 
ATOM   5566 N N     . ASN   A 1 913  ? 202.262 121.382 111.905 1.00 28.28  ? 913  ASN   C N     1 
ATOM   5567 C CA    . ASN   A 1 913  ? 201.510 120.311 111.268 1.00 23.15  ? 913  ASN   C CA    1 
ATOM   5568 C C     . ASN   A 1 913  ? 200.146 120.803 110.803 1.00 19.95  ? 913  ASN   C C     1 
ATOM   5569 O O     . ASN   A 1 913  ? 199.612 120.315 109.810 1.00 19.21  ? 913  ASN   C O     1 
ATOM   5570 C CB    . ASN   A 1 913  ? 201.369 119.129 112.206 1.00 23.46  ? 913  ASN   C CB    1 
ATOM   5571 C CG    . ASN   A 1 913  ? 202.682 118.448 112.452 1.00 28.09  ? 913  ASN   C CG    1 
ATOM   5572 O OD1   . ASN   A 1 913  ? 203.537 118.392 111.561 1.00 29.80  ? 913  ASN   C OD1   1 
ATOM   5573 N ND2   . ASN   A 1 913  ? 202.866 117.933 113.638 1.00 29.83  ? 913  ASN   C ND2   1 
ATOM   5574 N N     . LEU   A 1 914  ? 199.592 121.785 111.506 1.00 18.33  ? 914  LEU   C N     1 
ATOM   5575 C CA    . LEU   A 1 914  ? 198.265 122.291 111.166 1.00 12.65  ? 914  LEU   C CA    1 
ATOM   5576 C C     . LEU   A 1 914  ? 198.270 122.929 109.781 1.00 13.27  ? 914  LEU   C C     1 
ATOM   5577 O O     . LEU   A 1 914  ? 199.046 123.847 109.516 1.00 18.24  ? 914  LEU   C O     1 
ATOM   5578 C CB    . LEU   A 1 914  ? 197.812 123.320 112.218 1.00 12.19  ? 914  LEU   C CB    1 
ATOM   5579 C CG    . LEU   A 1 914  ? 196.387 123.918 112.058 1.00 7.31   ? 914  LEU   C CG    1 
ATOM   5580 C CD1   . LEU   A 1 914  ? 195.336 122.837 112.277 1.00 6.43   ? 914  LEU   C CD1   1 
ATOM   5581 C CD2   . LEU   A 1 914  ? 196.205 125.040 113.066 1.00 11.34  ? 914  LEU   C CD2   1 
ATOM   5582 N N     . THR   A 1 915  ? 197.392 122.445 108.897 1.00 11.67  ? 915  THR   C N     1 
ATOM   5583 C CA    . THR   A 1 915  ? 197.308 122.971 107.535 1.00 9.96   ? 915  THR   C CA    1 
ATOM   5584 C C     . THR   A 1 915  ? 195.944 123.554 107.174 1.00 9.26   ? 915  THR   C C     1 
ATOM   5585 O O     . THR   A 1 915  ? 195.851 124.367 106.252 1.00 17.77  ? 915  THR   C O     1 
ATOM   5586 C CB    . THR   A 1 915  ? 197.685 121.905 106.490 1.00 9.51   ? 915  THR   C CB    1 
ATOM   5587 O OG1   . THR   A 1 915  ? 196.846 120.756 106.643 1.00 10.14  ? 915  THR   C OG1   1 
ATOM   5588 C CG2   . THR   A 1 915  ? 199.135 121.509 106.637 1.00 12.50  ? 915  THR   C CG2   1 
ATOM   5589 N N     . HIS   A 1 916  ? 194.891 123.162 107.889 1.00 7.19   ? 916  HIS   C N     1 
ATOM   5590 C CA    . HIS   A 1 916  ? 193.551 123.654 107.565 1.00 5.67   ? 916  HIS   C CA    1 
ATOM   5591 C C     . HIS   A 1 916  ? 192.805 124.129 108.806 1.00 0.23   ? 916  HIS   C C     1 
ATOM   5592 O O     . HIS   A 1 916  ? 192.666 123.388 109.781 1.00 3.03   ? 916  HIS   C O     1 
ATOM   5593 C CB    . HIS   A 1 916  ? 192.714 122.565 106.887 1.00 6.69   ? 916  HIS   C CB    1 
ATOM   5594 C CG    . HIS   A 1 916  ? 193.265 122.045 105.586 1.00 8.61   ? 916  HIS   C CG    1 
ATOM   5595 N ND1   . HIS   A 1 916  ? 194.390 121.247 105.513 1.00 10.11  ? 916  HIS   C ND1   1 
ATOM   5596 C CD2   . HIS   A 1 916  ? 192.828 122.191 104.318 1.00 9.99   ? 916  HIS   C CD2   1 
ATOM   5597 C CE1   . HIS   A 1 916  ? 194.629 120.946 104.249 1.00 11.17  ? 916  HIS   C CE1   1 
ATOM   5598 N NE2   . HIS   A 1 916  ? 193.694 121.503 103.506 1.00 11.70  ? 916  HIS   C NE2   1 
ATOM   5599 N N     . LEU   A 1 917  ? 192.309 125.360 108.754 1.00 0.44   ? 917  LEU   C N     1 
ATOM   5600 C CA    . LEU   A 1 917  ? 191.568 125.935 109.872 1.00 0.30   ? 917  LEU   C CA    1 
ATOM   5601 C C     . LEU   A 1 917  ? 190.271 126.565 109.377 1.00 0.06   ? 917  LEU   C C     1 
ATOM   5602 O O     . LEU   A 1 917  ? 190.288 127.411 108.481 1.00 12.66  ? 917  LEU   C O     1 
ATOM   5603 C CB    . LEU   A 1 917  ? 192.447 126.976 110.584 1.00 10.48  ? 917  LEU   C CB    1 
ATOM   5604 C CG    . LEU   A 1 917  ? 191.842 127.711 111.792 1.00 0.27   ? 917  LEU   C CG    1 
ATOM   5605 C CD1   . LEU   A 1 917  ? 191.574 126.719 112.926 1.00 0.75   ? 917  LEU   C CD1   1 
ATOM   5606 C CD2   . LEU   A 1 917  ? 192.816 128.801 112.248 1.00 11.97  ? 917  LEU   C CD2   1 
ATOM   5607 N N     . TYR   A 1 918  ? 189.147 126.125 109.934 1.00 0.23   ? 918  TYR   C N     1 
ATOM   5608 C CA    . TYR   A 1 918  ? 187.842 126.592 109.473 1.00 0.06   ? 918  TYR   C CA    1 
ATOM   5609 C C     . TYR   A 1 918  ? 187.118 127.386 110.554 1.00 0.06   ? 918  TYR   C C     1 
ATOM   5610 O O     . TYR   A 1 918  ? 186.686 126.813 111.548 1.00 0.07   ? 918  TYR   C O     1 
ATOM   5611 C CB    . TYR   A 1 918  ? 186.991 125.392 109.059 1.00 0.19   ? 918  TYR   C CB    1 
ATOM   5612 C CG    . TYR   A 1 918  ? 187.668 124.488 108.052 1.00 0.51   ? 918  TYR   C CG    1 
ATOM   5613 C CD1   . TYR   A 1 918  ? 188.370 123.381 108.489 1.00 0.55   ? 918  TYR   C CD1   1 
ATOM   5614 C CD2   . TYR   A 1 918  ? 187.600 124.764 106.707 1.00 2.21   ? 918  TYR   C CD2   1 
ATOM   5615 C CE1   . TYR   A 1 918  ? 188.994 122.559 107.581 1.00 0.55   ? 918  TYR   C CE1   1 
ATOM   5616 C CE2   . TYR   A 1 918  ? 188.225 123.943 105.799 1.00 0.61   ? 918  TYR   C CE2   1 
ATOM   5617 C CZ    . TYR   A 1 918  ? 188.919 122.847 106.233 1.00 2.55   ? 918  TYR   C CZ    1 
ATOM   5618 O OH    . TYR   A 1 918  ? 189.542 122.030 105.324 1.00 8.47   ? 918  TYR   C OH    1 
ATOM   5619 N N     . LEU   A 1 919  ? 187.008 128.704 110.381 1.00 4.29   ? 919  LEU   C N     1 
ATOM   5620 C CA    . LEU   A 1 919  ? 186.419 129.551 111.421 1.00 1.95   ? 919  LEU   C CA    1 
ATOM   5621 C C     . LEU   A 1 919  ? 185.070 130.169 111.050 1.00 6.08   ? 919  LEU   C C     1 
ATOM   5622 O O     . LEU   A 1 919  ? 184.586 131.069 111.741 1.00 7.59   ? 919  LEU   C O     1 
ATOM   5623 C CB    . LEU   A 1 919  ? 187.401 130.669 111.785 1.00 10.08  ? 919  LEU   C CB    1 
ATOM   5624 C CG    . LEU   A 1 919  ? 188.751 130.211 112.353 1.00 7.17   ? 919  LEU   C CG    1 
ATOM   5625 C CD1   . LEU   A 1 919  ? 189.665 131.412 112.505 1.00 7.99   ? 919  LEU   C CD1   1 
ATOM   5626 C CD2   . LEU   A 1 919  ? 188.545 129.519 113.705 1.00 11.52  ? 919  LEU   C CD2   1 
ATOM   5627 N N     . ARG   A 1 920  ? 184.463 129.713 109.966 1.00 5.71   ? 920  ARG   C N     1 
ATOM   5628 C CA    . ARG   A 1 920  ? 183.212 130.322 109.533 1.00 5.92   ? 920  ARG   C CA    1 
ATOM   5629 C C     . ARG   A 1 920  ? 182.106 130.180 110.563 1.00 6.24   ? 920  ARG   C C     1 
ATOM   5630 O O     . ARG   A 1 920  ? 181.819 129.080 111.017 1.00 11.12  ? 920  ARG   C O     1 
ATOM   5631 C CB    . ARG   A 1 920  ? 182.739 129.702 108.229 1.00 8.13   ? 920  ARG   C CB    1 
ATOM   5632 C CG    . ARG   A 1 920  ? 182.395 128.243 108.247 1.00 8.53   ? 920  ARG   C CG    1 
ATOM   5633 C CD    . ARG   A 1 920  ? 182.065 127.743 106.881 1.00 8.93   ? 920  ARG   C CD    1 
ATOM   5634 N NE    . ARG   A 1 920  ? 180.897 128.415 106.311 1.00 12.14  ? 920  ARG   C NE    1 
ATOM   5635 C CZ    . ARG   A 1 920  ? 179.614 128.091 106.549 1.00 14.12  ? 920  ARG   C CZ    1 
ATOM   5636 N NH1   . ARG   A 1 920  ? 179.302 127.099 107.360 1.00 12.02  ? 920  ARG   C NH1   1 
ATOM   5637 N NH2   . ARG   A 1 920  ? 178.667 128.789 105.949 1.00 16.42  ? 920  ARG   C NH2   1 
ATOM   5638 N N     . GLY   A 1 921  ? 181.426 131.279 110.874 1.00 7.37   ? 921  GLY   C N     1 
ATOM   5639 C CA    . GLY   A 1 921  ? 180.317 131.245 111.823 1.00 7.03   ? 921  GLY   C CA    1 
ATOM   5640 C C     . GLY   A 1 921  ? 180.652 131.895 113.165 1.00 7.96   ? 921  GLY   C C     1 
ATOM   5641 O O     . GLY   A 1 921  ? 179.753 132.202 113.948 1.00 10.18  ? 921  GLY   C O     1 
ATOM   5642 N N     . ASN   A 1 922  ? 181.931 132.128 113.430 1.00 7.78   ? 922  ASN   C N     1 
ATOM   5643 C CA    . ASN   A 1 922  ? 182.315 132.781 114.674 1.00 7.50   ? 922  ASN   C CA    1 
ATOM   5644 C C     . ASN   A 1 922  ? 182.123 134.285 114.520 1.00 12.78  ? 922  ASN   C C     1 
ATOM   5645 O O     . ASN   A 1 922  ? 181.755 134.748 113.445 1.00 16.00  ? 922  ASN   C O     1 
ATOM   5646 C CB    . ASN   A 1 922  ? 183.753 132.450 115.019 1.00 9.05   ? 922  ASN   C CB    1 
ATOM   5647 C CG    . ASN   A 1 922  ? 183.962 130.992 115.310 1.00 7.34   ? 922  ASN   C CG    1 
ATOM   5648 O OD1   . ASN   A 1 922  ? 183.400 130.428 116.261 1.00 10.12  ? 922  ASN   C OD1   1 
ATOM   5649 N ND2   . ASN   A 1 922  ? 184.769 130.368 114.494 1.00 5.41   ? 922  ASN   C ND2   1 
ATOM   5650 N N     . THR   A 1 923  ? 182.386 135.052 115.575 1.00 13.79  ? 923  THR   C N     1 
ATOM   5651 C CA    . THR   A 1 923  ? 182.304 136.513 115.495 1.00 13.15  ? 923  THR   C CA    1 
ATOM   5652 C C     . THR   A 1 923  ? 183.642 137.115 115.879 1.00 14.95  ? 923  THR   C C     1 
ATOM   5653 O O     . THR   A 1 923  ? 183.925 137.319 117.058 1.00 20.46  ? 923  THR   C O     1 
ATOM   5654 C CB    . THR   A 1 923  ? 181.202 137.073 116.415 1.00 12.47  ? 923  THR   C CB    1 
ATOM   5655 O OG1   . THR   A 1 923  ? 179.939 136.496 116.059 1.00 16.23  ? 923  THR   C OG1   1 
ATOM   5656 C CG2   . THR   A 1 923  ? 181.119 138.584 116.279 1.00 16.85  ? 923  THR   C CG2   1 
ATOM   5657 N N     . LEU   A 1 924  ? 184.489 137.348 114.889 1.00 15.72  ? 924  LEU   C N     1 
ATOM   5658 C CA    . LEU   A 1 924  ? 185.861 137.722 115.181 1.00 18.61  ? 924  LEU   C CA    1 
ATOM   5659 C C     . LEU   A 1 924  ? 186.089 139.212 114.979 1.00 20.82  ? 924  LEU   C C     1 
ATOM   5660 O O     . LEU   A 1 924  ? 186.816 139.853 115.742 1.00 26.64  ? 924  LEU   C O     1 
ATOM   5661 C CB    . LEU   A 1 924  ? 186.795 136.918 114.275 1.00 20.73  ? 924  LEU   C CB    1 
ATOM   5662 C CG    . LEU   A 1 924  ? 186.630 135.382 114.330 1.00 13.07  ? 924  LEU   C CG    1 
ATOM   5663 C CD1   . LEU   A 1 924  ? 187.613 134.760 113.364 1.00 14.60  ? 924  LEU   C CD1   1 
ATOM   5664 C CD2   . LEU   A 1 924  ? 186.844 134.876 115.746 1.00 15.00  ? 924  LEU   C CD2   1 
ATOM   5665 N N     . GLY   A 1 925  ? 185.460 139.764 113.954 1.00 22.62  ? 925  GLY   C N     1 
ATOM   5666 C CA    . GLY   A 1 925  ? 185.618 141.173 113.644 1.00 27.01  ? 925  GLY   C CA    1 
ATOM   5667 C C     . GLY   A 1 925  ? 187.024 141.458 113.149 1.00 30.43  ? 925  GLY   C C     1 
ATOM   5668 O O     . GLY   A 1 925  ? 187.788 140.541 112.837 1.00 31.96  ? 925  GLY   C O     1 
ATOM   5669 N N     . ASP   A 1 926  ? 187.380 142.732 113.106 1.00 31.87  ? 926  ASP   C N     1 
ATOM   5670 C CA    . ASP   A 1 926  ? 188.688 143.130 112.625 1.00 34.91  ? 926  ASP   C CA    1 
ATOM   5671 C C     . ASP   A 1 926  ? 189.769 142.850 113.658 1.00 39.49  ? 926  ASP   C C     1 
ATOM   5672 O O     . ASP   A 1 926  ? 190.923 142.600 113.304 1.00 41.08  ? 926  ASP   C O     1 
ATOM   5673 C CB    . ASP   A 1 926  ? 188.668 144.611 112.261 1.00 38.03  ? 926  ASP   C CB    1 
ATOM   5674 C CG    . ASP   A 1 926  ? 188.150 145.455 113.411 1.00 43.47  ? 926  ASP   C CG    1 
ATOM   5675 O OD1   . ASP   A 1 926  ? 187.208 145.013 114.039 1.00 44.86  ? 926  ASP   C OD1   1 
ATOM   5676 O OD2   . ASP   A 1 926  ? 188.683 146.515 113.665 1.00 47.28  ? 926  ASP   C OD2   1 
ATOM   5677 N N     . LYS   A 1 927  ? 189.399 142.856 114.935 1.00 37.27  ? 927  LYS   C N     1 
ATOM   5678 C CA    . LYS   A 1 927  ? 190.378 142.614 115.982 1.00 37.95  ? 927  LYS   C CA    1 
ATOM   5679 C C     . LYS   A 1 927  ? 190.860 141.176 115.917 1.00 38.81  ? 927  LYS   C C     1 
ATOM   5680 O O     . LYS   A 1 927  ? 192.054 140.904 116.062 1.00 40.52  ? 927  LYS   C O     1 
ATOM   5681 C CB    . LYS   A 1 927  ? 189.791 142.915 117.363 1.00 35.57  ? 927  LYS   C CB    1 
ATOM   5682 C CG    . LYS   A 1 927  ? 189.912 144.379 117.798 1.00 42.89  ? 927  LYS   C CG    1 
ATOM   5683 C CD    . LYS   A 1 927  ? 188.986 145.275 116.983 1.00 44.19  ? 927  LYS   C CD    1 
ATOM   5684 C CE    . LYS   A 1 927  ? 189.167 146.743 117.311 1.00 45.76  ? 927  LYS   C CE    1 
ATOM   5685 N NZ    . LYS   A 1 927  ? 188.332 147.602 116.417 1.00 46.23  ? 927  LYS   C NZ    1 
ATOM   5686 N N     . GLY   A 1 928  ? 189.936 140.253 115.668 1.00 33.97  ? 928  GLY   C N     1 
ATOM   5687 C CA    . GLY   A 1 928  ? 190.297 138.854 115.556 1.00 33.44  ? 928  GLY   C CA    1 
ATOM   5688 C C     . GLY   A 1 928  ? 191.222 138.622 114.372 1.00 35.31  ? 928  GLY   C C     1 
ATOM   5689 O O     . GLY   A 1 928  ? 192.198 137.877 114.474 1.00 36.87  ? 928  GLY   C O     1 
ATOM   5690 N N     . ILE   A 1 929  ? 190.948 139.296 113.256 1.00 36.72  ? 929  ILE   C N     1 
ATOM   5691 C CA    . ILE   A 1 929  ? 191.800 139.148 112.084 1.00 37.94  ? 929  ILE   C CA    1 
ATOM   5692 C C     . ILE   A 1 929  ? 193.210 139.627 112.377 1.00 40.26  ? 929  ILE   C C     1 
ATOM   5693 O O     . ILE   A 1 929  ? 194.178 138.969 111.993 1.00 40.74  ? 929  ILE   C O     1 
ATOM   5694 C CB    . ILE   A 1 929  ? 191.238 139.915 110.872 1.00 34.17  ? 929  ILE   C CB    1 
ATOM   5695 C CG1   . ILE   A 1 929  ? 189.883 139.317 110.433 1.00 33.44  ? 929  ILE   C CG1   1 
ATOM   5696 C CG2   . ILE   A 1 929  ? 192.246 139.917 109.714 1.00 39.38  ? 929  ILE   C CG2   1 
ATOM   5697 C CD1   . ILE   A 1 929  ? 189.909 137.860 109.997 1.00 32.47  ? 929  ILE   C CD1   1 
ATOM   5698 N N     . LYS   A 1 930  ? 193.336 140.762 113.061 1.00 39.91  ? 930  LYS   C N     1 
ATOM   5699 C CA    . LYS   A 1 930  ? 194.660 141.281 113.379 1.00 42.03  ? 930  LYS   C CA    1 
ATOM   5700 C C     . LYS   A 1 930  ? 195.461 140.288 114.212 1.00 41.88  ? 930  LYS   C C     1 
ATOM   5701 O O     . LYS   A 1 930  ? 196.635 140.039 113.928 1.00 45.58  ? 930  LYS   C O     1 
ATOM   5702 C CB    . LYS   A 1 930  ? 194.550 142.612 114.121 1.00 43.18  ? 930  LYS   C CB    1 
ATOM   5703 C CG    . LYS   A 1 930  ? 194.102 143.769 113.249 1.00 45.98  ? 930  LYS   C CG    1 
ATOM   5704 C CD    . LYS   A 1 930  ? 193.998 145.070 114.033 1.00 50.87  ? 930  LYS   C CD    1 
ATOM   5705 C CE    . LYS   A 1 930  ? 193.422 146.196 113.170 1.00 51.70  ? 930  LYS   C CE    1 
ATOM   5706 N NZ    . LYS   A 1 930  ? 194.327 146.564 112.031 1.00 56.87  ? 930  LYS   C NZ    1 
ATOM   5707 N N     . LEU   A 1 931  ? 194.825 139.693 115.218 1.00 38.64  ? 931  LEU   C N     1 
ATOM   5708 C CA    . LEU   A 1 931  ? 195.515 138.721 116.058 1.00 40.28  ? 931  LEU   C CA    1 
ATOM   5709 C C     . LEU   A 1 931  ? 195.906 137.476 115.269 1.00 41.30  ? 931  LEU   C C     1 
ATOM   5710 O O     . LEU   A 1 931  ? 197.017 136.955 115.414 1.00 41.50  ? 931  LEU   C O     1 
ATOM   5711 C CB    . LEU   A 1 931  ? 194.625 138.331 117.245 1.00 39.67  ? 931  LEU   C CB    1 
ATOM   5712 C CG    . LEU   A 1 931  ? 194.430 139.403 118.337 1.00 38.90  ? 931  LEU   C CG    1 
ATOM   5713 C CD1   . LEU   A 1 931  ? 193.316 138.963 119.283 1.00 36.83  ? 931  LEU   C CD1   1 
ATOM   5714 C CD2   . LEU   A 1 931  ? 195.736 139.587 119.109 1.00 42.15  ? 931  LEU   C CD2   1 
ATOM   5715 N N     . LEU   A 1 932  ? 195.013 137.004 114.406 1.00 38.54  ? 932  LEU   C N     1 
ATOM   5716 C CA    . LEU   A 1 932  ? 195.333 135.831 113.611 1.00 37.19  ? 932  LEU   C CA    1 
ATOM   5717 C C     . LEU   A 1 932  ? 196.487 136.130 112.676 1.00 41.14  ? 932  LEU   C C     1 
ATOM   5718 O O     . LEU   A 1 932  ? 197.364 135.292 112.485 1.00 42.04  ? 932  LEU   C O     1 
ATOM   5719 C CB    . LEU   A 1 932  ? 194.121 135.372 112.789 1.00 33.16  ? 932  LEU   C CB    1 
ATOM   5720 C CG    . LEU   A 1 932  ? 192.947 134.752 113.572 1.00 31.12  ? 932  LEU   C CG    1 
ATOM   5721 C CD1   . LEU   A 1 932  ? 191.766 134.568 112.627 1.00 31.31  ? 932  LEU   C CD1   1 
ATOM   5722 C CD2   . LEU   A 1 932  ? 193.371 133.407 114.172 1.00 27.14  ? 932  LEU   C CD2   1 
ATOM   5723 N N     . CYS   A 1 933  ? 196.503 137.335 112.112 1.00 40.45  ? 933  CYS   C N     1 
ATOM   5724 C CA    . CYS   A 1 933  ? 197.552 137.726 111.183 1.00 41.16  ? 933  CYS   C CA    1 
ATOM   5725 C C     . CYS   A 1 933  ? 198.922 137.722 111.842 1.00 41.69  ? 933  CYS   C C     1 
ATOM   5726 O O     . CYS   A 1 933  ? 199.916 137.354 111.216 1.00 46.37  ? 933  CYS   C O     1 
ATOM   5727 C CB    . CYS   A 1 933  ? 197.264 139.096 110.589 1.00 42.48  ? 933  CYS   C CB    1 
ATOM   5728 S SG    . CYS   A 1 933  ? 195.868 139.087 109.461 1.00 46.74  ? 933  CYS   C SG    1 
ATOM   5729 N N     . GLU   A 1 934  ? 198.991 138.093 113.114 1.00 43.56  ? 934  GLU   C N     1 
ATOM   5730 C CA    . GLU   A 1 934  ? 200.277 138.074 113.797 1.00 46.51  ? 934  GLU   C CA    1 
ATOM   5731 C C     . GLU   A 1 934  ? 200.851 136.660 113.794 1.00 47.20  ? 934  GLU   C C     1 
ATOM   5732 O O     . GLU   A 1 934  ? 202.058 136.469 113.640 1.00 48.52  ? 934  GLU   C O     1 
ATOM   5733 C CB    . GLU   A 1 934  ? 200.148 138.589 115.233 1.00 48.77  ? 934  GLU   C CB    1 
ATOM   5734 C CG    . GLU   A 1 934  ? 199.905 140.091 115.352 1.00 53.34  ? 934  GLU   C CG    1 
ATOM   5735 C CD    . GLU   A 1 934  ? 199.773 140.551 116.782 1.00 60.46  ? 934  GLU   C CD    1 
ATOM   5736 O OE1   . GLU   A 1 934  ? 199.678 139.714 117.648 1.00 54.86  ? 934  GLU   C OE1   1 
ATOM   5737 O OE2   . GLU   A 1 934  ? 199.771 141.739 117.007 1.00 64.41  ? 934  GLU   C OE2   1 
ATOM   5738 N N     . GLY   A 1 935  ? 199.975 135.668 113.948 1.00 45.04  ? 935  GLY   C N     1 
ATOM   5739 C CA    . GLY   A 1 935  ? 200.384 134.265 113.902 1.00 44.19  ? 935  GLY   C CA    1 
ATOM   5740 C C     . GLY   A 1 935  ? 200.595 133.776 112.465 1.00 41.33  ? 935  GLY   C C     1 
ATOM   5741 O O     . GLY   A 1 935  ? 201.571 133.089 112.165 1.00 41.30  ? 935  GLY   C O     1 
ATOM   5742 N N     . LEU   A 1 936  ? 199.679 134.139 111.574 1.00 40.72  ? 936  LEU   C N     1 
ATOM   5743 C CA    . LEU   A 1 936  ? 199.708 133.676 110.190 1.00 40.93  ? 936  LEU   C CA    1 
ATOM   5744 C C     . LEU   A 1 936  ? 200.931 134.180 109.438 1.00 46.12  ? 936  LEU   C C     1 
ATOM   5745 O O     . LEU   A 1 936  ? 201.454 133.493 108.562 1.00 47.93  ? 936  LEU   C O     1 
ATOM   5746 C CB    . LEU   A 1 936  ? 198.451 134.140 109.455 1.00 39.19  ? 936  LEU   C CB    1 
ATOM   5747 C CG    . LEU   A 1 936  ? 197.130 133.494 109.869 1.00 34.60  ? 936  LEU   C CG    1 
ATOM   5748 C CD1   . LEU   A 1 936  ? 195.981 134.304 109.313 1.00 35.99  ? 936  LEU   C CD1   1 
ATOM   5749 C CD2   . LEU   A 1 936  ? 197.070 132.084 109.337 1.00 33.94  ? 936  LEU   C CD2   1 
ATOM   5750 N N     . LEU   A 1 937  ? 201.387 135.381 109.779 1.00 44.96  ? 937  LEU   C N     1 
ATOM   5751 C CA    . LEU   A 1 937  ? 202.532 135.995 109.117 1.00 45.04  ? 937  LEU   C CA    1 
ATOM   5752 C C     . LEU   A 1 937  ? 203.861 135.499 109.669 1.00 47.20  ? 937  LEU   C C     1 
ATOM   5753 O O     . LEU   A 1 937  ? 204.924 135.913 109.204 1.00 48.90  ? 937  LEU   C O     1 
ATOM   5754 C CB    . LEU   A 1 937  ? 202.457 137.518 109.263 1.00 47.57  ? 937  LEU   C CB    1 
ATOM   5755 C CG    . LEU   A 1 937  ? 201.288 138.208 108.537 1.00 51.37  ? 937  LEU   C CG    1 
ATOM   5756 C CD1   . LEU   A 1 937  ? 201.217 139.663 108.966 1.00 53.42  ? 937  LEU   C CD1   1 
ATOM   5757 C CD2   . LEU   A 1 937  ? 201.497 138.116 107.035 1.00 54.41  ? 937  LEU   C CD2   1 
ATOM   5758 N N     . HIS   A 1 938  ? 203.808 134.621 110.662 1.00 47.12  ? 938  HIS   C N     1 
ATOM   5759 C CA    . HIS   A 1 938  ? 205.014 134.048 111.237 1.00 48.55  ? 938  HIS   C CA    1 
ATOM   5760 C C     . HIS   A 1 938  ? 205.683 133.160 110.179 1.00 49.76  ? 938  HIS   C C     1 
ATOM   5761 O O     . HIS   A 1 938  ? 204.986 132.442 109.464 1.00 49.13  ? 938  HIS   C O     1 
ATOM   5762 C CB    . HIS   A 1 938  ? 204.656 133.232 112.489 1.00 49.68  ? 938  HIS   C CB    1 
ATOM   5763 C CG    . HIS   A 1 938  ? 205.821 132.818 113.307 1.00 51.50  ? 938  HIS   C CG    1 
ATOM   5764 N ND1   . HIS   A 1 938  ? 206.644 131.774 112.953 1.00 52.04  ? 938  HIS   C ND1   1 
ATOM   5765 C CD2   . HIS   A 1 938  ? 206.316 133.312 114.465 1.00 52.16  ? 938  HIS   C CD2   1 
ATOM   5766 C CE1   . HIS   A 1 938  ? 207.596 131.643 113.863 1.00 52.65  ? 938  HIS   C CE1   1 
ATOM   5767 N NE2   . HIS   A 1 938  ? 207.419 132.565 114.785 1.00 52.76  ? 938  HIS   C NE2   1 
ATOM   5768 N N     . PRO   A 1 939  ? 207.016 133.187 110.045 1.00 51.35  ? 939  PRO   C N     1 
ATOM   5769 C CA    . PRO   A 1 939  ? 207.785 132.428 109.071 1.00 53.03  ? 939  PRO   C CA    1 
ATOM   5770 C C     . PRO   A 1 939  ? 207.607 130.912 109.177 1.00 52.40  ? 939  PRO   C C     1 
ATOM   5771 O O     . PRO   A 1 939  ? 207.835 130.198 108.202 1.00 51.53  ? 939  PRO   C O     1 
ATOM   5772 C CB    . PRO   A 1 939  ? 209.232 132.848 109.383 1.00 53.46  ? 939  PRO   C CB    1 
ATOM   5773 C CG    . PRO   A 1 939  ? 209.190 133.425 110.781 1.00 53.85  ? 939  PRO   C CG    1 
ATOM   5774 C CD    . PRO   A 1 939  ? 207.834 134.068 110.894 1.00 52.09  ? 939  PRO   C CD    1 
ATOM   5775 N N     . ASP   A 1 940  ? 207.196 130.414 110.344 1.00 51.32  ? 940  ASP   C N     1 
ATOM   5776 C CA    . ASP   A 1 940  ? 207.019 128.975 110.505 1.00 52.53  ? 940  ASP   C CA    1 
ATOM   5777 C C     . ASP   A 1 940  ? 205.563 128.545 110.338 1.00 47.24  ? 940  ASP   C C     1 
ATOM   5778 O O     . ASP   A 1 940  ? 205.224 127.389 110.590 1.00 44.01  ? 940  ASP   C O     1 
ATOM   5779 C CB    . ASP   A 1 940  ? 207.527 128.513 111.874 1.00 54.21  ? 940  ASP   C CB    1 
ATOM   5780 C CG    . ASP   A 1 940  ? 209.041 128.689 112.055 1.00 55.46  ? 940  ASP   C CG    1 
ATOM   5781 O OD1   . ASP   A 1 940  ? 209.755 128.639 111.081 1.00 55.48  ? 940  ASP   C OD1   1 
ATOM   5782 O OD2   . ASP   A 1 940  ? 209.468 128.850 113.174 1.00 56.05  ? 940  ASP   C OD2   1 
ATOM   5783 N N     . CYS   A 1 941  ? 204.697 129.461 109.916 1.00 43.26  ? 941  CYS   C N     1 
ATOM   5784 C CA    . CYS   A 1 941  ? 203.296 129.108 109.718 1.00 40.07  ? 941  CYS   C CA    1 
ATOM   5785 C C     . CYS   A 1 941  ? 203.109 128.356 108.406 1.00 40.06  ? 941  CYS   C C     1 
ATOM   5786 O O     . CYS   A 1 941  ? 203.511 128.831 107.343 1.00 40.66  ? 941  CYS   C O     1 
ATOM   5787 C CB    . CYS   A 1 941  ? 202.410 130.348 109.711 1.00 41.37  ? 941  CYS   C CB    1 
ATOM   5788 S SG    . CYS   A 1 941  ? 200.656 129.985 109.490 1.00 43.38  ? 941  CYS   C SG    1 
ATOM   5789 N N     . LYS   A 1 942  ? 202.515 127.171 108.484 1.00 37.01  ? 942  LYS   C N     1 
ATOM   5790 C CA    . LYS   A 1 942  ? 202.338 126.330 107.307 1.00 29.64  ? 942  LYS   C CA    1 
ATOM   5791 C C     . LYS   A 1 942  ? 200.877 126.209 106.892 1.00 24.52  ? 942  LYS   C C     1 
ATOM   5792 O O     . LYS   A 1 942  ? 200.534 125.365 106.066 1.00 23.04  ? 942  LYS   C O     1 
ATOM   5793 C CB    . LYS   A 1 942  ? 202.923 124.941 107.561 1.00 29.36  ? 942  LYS   C CB    1 
ATOM   5794 C CG    . LYS   A 1 942  ? 204.411 124.936 107.935 1.00 37.10  ? 942  LYS   C CG    1 
ATOM   5795 C CD    . LYS   A 1 942  ? 205.296 125.455 106.802 1.00 39.44  ? 942  LYS   C CD    1 
ATOM   5796 C CE    . LYS   A 1 942  ? 206.770 125.355 107.170 1.00 45.46  ? 942  LYS   C CE    1 
ATOM   5797 N NZ    . LYS   A 1 942  ? 207.652 125.869 106.083 1.00 50.56  ? 942  LYS   C NZ    1 
ATOM   5798 N N     . LEU   A 1 943  ? 200.013 127.038 107.468 1.00 23.39  ? 943  LEU   C N     1 
ATOM   5799 C CA    . LEU   A 1 943  ? 198.592 126.949 107.159 1.00 17.50  ? 943  LEU   C CA    1 
ATOM   5800 C C     . LEU   A 1 943  ? 198.374 127.148 105.667 1.00 21.09  ? 943  LEU   C C     1 
ATOM   5801 O O     . LEU   A 1 943  ? 198.863 128.118 105.089 1.00 25.14  ? 943  LEU   C O     1 
ATOM   5802 C CB    . LEU   A 1 943  ? 197.799 128.017 107.931 1.00 14.65  ? 943  LEU   C CB    1 
ATOM   5803 C CG    . LEU   A 1 943  ? 196.267 127.875 107.893 1.00 10.67  ? 943  LEU   C CG    1 
ATOM   5804 C CD1   . LEU   A 1 943  ? 195.850 126.693 108.753 1.00 11.81  ? 943  LEU   C CD1   1 
ATOM   5805 C CD2   . LEU   A 1 943  ? 195.621 129.144 108.380 1.00 13.17  ? 943  LEU   C CD2   1 
ATOM   5806 N N     . GLN   A 1 944  ? 197.633 126.235 105.043 1.00 17.35  ? 944  GLN   C N     1 
ATOM   5807 C CA    . GLN   A 1 944  ? 197.372 126.316 103.613 1.00 15.71  ? 944  GLN   C CA    1 
ATOM   5808 C C     . GLN   A 1 944  ? 195.980 126.853 103.333 1.00 13.93  ? 944  GLN   C C     1 
ATOM   5809 O O     . GLN   A 1 944  ? 195.781 127.634 102.401 1.00 25.94  ? 944  GLN   C O     1 
ATOM   5810 C CB    . GLN   A 1 944  ? 197.532 124.946 102.960 1.00 14.67  ? 944  GLN   C CB    1 
ATOM   5811 C CG    . GLN   A 1 944  ? 198.940 124.409 102.991 1.00 17.84  ? 944  GLN   C CG    1 
ATOM   5812 C CD    . GLN   A 1 944  ? 199.039 123.052 102.349 1.00 19.45  ? 944  GLN   C CD    1 
ATOM   5813 O OE1   . GLN   A 1 944  ? 198.061 122.554 101.784 1.00 17.69  ? 944  GLN   C OE1   1 
ATOM   5814 N NE2   . GLN   A 1 944  ? 200.212 122.438 102.428 1.00 20.13  ? 944  GLN   C NE2   1 
ATOM   5815 N N     . VAL   A 1 945  ? 195.016 126.431 104.140 1.00 10.36  ? 945  VAL   C N     1 
ATOM   5816 C CA    . VAL   A 1 945  ? 193.643 126.854 103.937 1.00 8.69   ? 945  VAL   C CA    1 
ATOM   5817 C C     . VAL   A 1 945  ? 193.065 127.563 105.138 1.00 9.29   ? 945  VAL   C C     1 
ATOM   5818 O O     . VAL   A 1 945  ? 192.929 126.981 106.215 1.00 11.57  ? 945  VAL   C O     1 
ATOM   5819 C CB    . VAL   A 1 945  ? 192.758 125.647 103.614 1.00 9.46   ? 945  VAL   C CB    1 
ATOM   5820 C CG1   . VAL   A 1 945  ? 191.309 126.084 103.479 1.00 10.53  ? 945  VAL   C CG1   1 
ATOM   5821 C CG2   . VAL   A 1 945  ? 193.246 124.995 102.329 1.00 17.15  ? 945  VAL   C CG2   1 
ATOM   5822 N N     . LEU   A 1 946  ? 192.663 128.805 104.928 1.00 10.04  ? 946  LEU   C N     1 
ATOM   5823 C CA    . LEU   A 1 946  ? 192.001 129.572 105.966 1.00 7.24   ? 946  LEU   C CA    1 
ATOM   5824 C C     . LEU   A 1 946  ? 190.610 129.958 105.498 1.00 7.93   ? 946  LEU   C C     1 
ATOM   5825 O O     . LEU   A 1 946  ? 190.458 130.679 104.509 1.00 15.70  ? 946  LEU   C O     1 
ATOM   5826 C CB    . LEU   A 1 946  ? 192.834 130.813 106.304 1.00 8.19   ? 946  LEU   C CB    1 
ATOM   5827 C CG    . LEU   A 1 946  ? 192.262 131.782 107.344 1.00 7.83   ? 946  LEU   C CG    1 
ATOM   5828 C CD1   . LEU   A 1 946  ? 192.085 131.077 108.685 1.00 8.68   ? 946  LEU   C CD1   1 
ATOM   5829 C CD2   . LEU   A 1 946  ? 193.222 132.945 107.491 1.00 11.96  ? 946  LEU   C CD2   1 
ATOM   5830 N N     . GLU   A 1 947  ? 189.593 129.465 106.187 1.00 6.05   ? 947  GLU   C N     1 
ATOM   5831 C CA    . GLU   A 1 947  ? 188.222 129.757 105.793 1.00 5.69   ? 947  GLU   C CA    1 
ATOM   5832 C C     . GLU   A 1 947  ? 187.585 130.779 106.726 1.00 5.89   ? 947  GLU   C C     1 
ATOM   5833 O O     . GLU   A 1 947  ? 187.501 130.561 107.937 1.00 6.24   ? 947  GLU   C O     1 
ATOM   5834 C CB    . GLU   A 1 947  ? 187.399 128.473 105.754 1.00 3.84   ? 947  GLU   C CB    1 
ATOM   5835 C CG    . GLU   A 1 947  ? 185.973 128.647 105.283 1.00 6.80   ? 947  GLU   C CG    1 
ATOM   5836 C CD    . GLU   A 1 947  ? 185.239 127.347 105.185 1.00 6.79   ? 947  GLU   C CD    1 
ATOM   5837 O OE1   . GLU   A 1 947  ? 184.992 126.750 106.205 1.00 7.94   ? 947  GLU   C OE1   1 
ATOM   5838 O OE2   . GLU   A 1 947  ? 184.934 126.938 104.092 1.00 12.71  ? 947  GLU   C OE2   1 
ATOM   5839 N N     . LEU   A 1 948  ? 187.150 131.903 106.162 1.00 7.48   ? 948  LEU   C N     1 
ATOM   5840 C CA    . LEU   A 1 948  ? 186.569 133.000 106.933 1.00 7.11   ? 948  LEU   C CA    1 
ATOM   5841 C C     . LEU   A 1 948  ? 185.254 133.483 106.344 1.00 10.29  ? 948  LEU   C C     1 
ATOM   5842 O O     . LEU   A 1 948  ? 185.187 134.575 105.767 1.00 16.33  ? 948  LEU   C O     1 
ATOM   5843 C CB    . LEU   A 1 948  ? 187.535 134.190 107.014 1.00 7.24   ? 948  LEU   C CB    1 
ATOM   5844 C CG    . LEU   A 1 948  ? 188.851 133.978 107.772 1.00 7.46   ? 948  LEU   C CG    1 
ATOM   5845 C CD1   . LEU   A 1 948  ? 189.799 135.132 107.464 1.00 9.02   ? 948  LEU   C CD1   1 
ATOM   5846 C CD2   . LEU   A 1 948  ? 188.579 133.914 109.271 1.00 9.46   ? 948  LEU   C CD2   1 
ATOM   5847 N N     . ASP   A 1 949  ? 184.204 132.702 106.520 1.00 10.06  ? 949  ASP   C N     1 
ATOM   5848 C CA    . ASP   A 1 949  ? 182.877 133.106 106.093 1.00 11.16  ? 949  ASP   C CA    1 
ATOM   5849 C C     . ASP   A 1 949  ? 182.358 134.049 107.145 1.00 12.54  ? 949  ASP   C C     1 
ATOM   5850 O O     . ASP   A 1 949  ? 183.074 134.345 108.095 1.00 13.91  ? 949  ASP   C O     1 
ATOM   5851 C CB    . ASP   A 1 949  ? 181.930 131.921 105.951 1.00 13.98  ? 949  ASP   C CB    1 
ATOM   5852 C CG    . ASP   A 1 949  ? 180.798 132.122 104.977 1.00 21.22  ? 949  ASP   C CG    1 
ATOM   5853 O OD1   . ASP   A 1 949  ? 180.443 133.252 104.724 1.00 28.41  ? 949  ASP   C OD1   1 
ATOM   5854 O OD2   . ASP   A 1 949  ? 180.274 131.135 104.510 1.00 19.39  ? 949  ASP   C OD2   1 
ATOM   5855 N N     . ASN   A 1 950  ? 181.146 134.544 106.975 1.00 16.08  ? 950  ASN   C N     1 
ATOM   5856 C CA    . ASN   A 1 950  ? 180.591 135.511 107.910 1.00 16.34  ? 950  ASN   C CA    1 
ATOM   5857 C C     . ASN   A 1 950  ? 181.229 135.419 109.289 1.00 14.90  ? 950  ASN   C C     1 
ATOM   5858 O O     . ASN   A 1 950  ? 180.800 134.628 110.128 1.00 17.96  ? 950  ASN   C O     1 
ATOM   5859 C CB    . ASN   A 1 950  ? 179.095 135.336 108.053 1.00 17.01  ? 950  ASN   C CB    1 
ATOM   5860 C CG    . ASN   A 1 950  ? 178.478 136.468 108.830 1.00 25.59  ? 950  ASN   C CG    1 
ATOM   5861 O OD1   . ASN   A 1 950  ? 179.181 137.310 109.422 1.00 26.77  ? 950  ASN   C OD1   1 
ATOM   5862 N ND2   . ASN   A 1 950  ? 177.169 136.509 108.847 1.00 27.78  ? 950  ASN   C ND2   1 
ATOM   5863 N N     . CYS   A 1 951  ? 182.220 136.275 109.529 1.00 15.95  ? 951  CYS   C N     1 
ATOM   5864 C CA    . CYS   A 1 951  ? 182.841 136.427 110.837 1.00 13.70  ? 951  CYS   C CA    1 
ATOM   5865 C C     . CYS   A 1 951  ? 182.650 137.850 111.322 1.00 19.49  ? 951  CYS   C C     1 
ATOM   5866 O O     . CYS   A 1 951  ? 183.436 138.350 112.131 1.00 21.64  ? 951  CYS   C O     1 
ATOM   5867 C CB    . CYS   A 1 951  ? 184.339 136.108 110.813 1.00 13.54  ? 951  CYS   C CB    1 
ATOM   5868 S SG    . CYS   A 1 951  ? 184.750 134.389 110.529 1.00 14.59  ? 951  CYS   C SG    1 
ATOM   5869 N N     . ASN   A 1 952  ? 181.608 138.506 110.809 1.00 19.75  ? 952  ASN   C N     1 
ATOM   5870 C CA    . ASN   A 1 952  ? 181.325 139.897 111.141 1.00 19.65  ? 952  ASN   C CA    1 
ATOM   5871 C C     . ASN   A 1 952  ? 182.514 140.801 110.841 1.00 24.57  ? 952  ASN   C C     1 
ATOM   5872 O O     . ASN   A 1 952  ? 182.877 141.650 111.654 1.00 28.18  ? 952  ASN   C O     1 
ATOM   5873 C CB    . ASN   A 1 952  ? 180.924 140.028 112.597 1.00 20.33  ? 952  ASN   C CB    1 
ATOM   5874 C CG    . ASN   A 1 952  ? 180.231 141.326 112.891 1.00 28.18  ? 952  ASN   C CG    1 
ATOM   5875 O OD1   . ASN   A 1 952  ? 179.508 141.865 112.044 1.00 34.80  ? 952  ASN   C OD1   1 
ATOM   5876 N ND2   . ASN   A 1 952  ? 180.433 141.843 114.077 1.00 30.30  ? 952  ASN   C ND2   1 
ATOM   5877 N N     . LEU   A 1 953  ? 183.118 140.618 109.672 1.00 26.77  ? 953  LEU   C N     1 
ATOM   5878 C CA    . LEU   A 1 953  ? 184.270 141.417 109.279 1.00 30.58  ? 953  LEU   C CA    1 
ATOM   5879 C C     . LEU   A 1 953  ? 183.847 142.696 108.583 1.00 34.31  ? 953  LEU   C C     1 
ATOM   5880 O O     . LEU   A 1 953  ? 182.785 142.758 107.962 1.00 37.52  ? 953  LEU   C O     1 
ATOM   5881 C CB    . LEU   A 1 953  ? 185.182 140.632 108.330 1.00 27.27  ? 953  LEU   C CB    1 
ATOM   5882 C CG    . LEU   A 1 953  ? 185.686 139.289 108.833 1.00 24.08  ? 953  LEU   C CG    1 
ATOM   5883 C CD1   . LEU   A 1 953  ? 186.590 138.678 107.775 1.00 21.76  ? 953  LEU   C CD1   1 
ATOM   5884 C CD2   . LEU   A 1 953  ? 186.415 139.472 110.154 1.00 26.53  ? 953  LEU   C CD2   1 
ATOM   5885 N N     . THR   A 1 954  ? 184.699 143.705 108.683 1.00 35.25  ? 954  THR   C N     1 
ATOM   5886 C CA    . THR   A 1 954  ? 184.497 144.985 108.028 1.00 41.58  ? 954  THR   C CA    1 
ATOM   5887 C C     . THR   A 1 954  ? 185.728 145.346 107.211 1.00 47.53  ? 954  THR   C C     1 
ATOM   5888 O O     . THR   A 1 954  ? 186.752 144.665 107.285 1.00 46.65  ? 954  THR   C O     1 
ATOM   5889 C CB    . THR   A 1 954  ? 184.212 146.093 109.052 1.00 46.49  ? 954  THR   C CB    1 
ATOM   5890 O OG1   . THR   A 1 954  ? 185.381 146.306 109.854 1.00 48.60  ? 954  THR   C OG1   1 
ATOM   5891 C CG2   . THR   A 1 954  ? 183.045 145.696 109.952 1.00 44.75  ? 954  THR   C CG2   1 
ATOM   5892 N N     . SER   A 1 955  ? 185.634 146.427 106.445 1.00 48.66  ? 955  SER   C N     1 
ATOM   5893 C CA    . SER   A 1 955  ? 186.706 146.853 105.547 1.00 50.34  ? 955  SER   C CA    1 
ATOM   5894 C C     . SER   A 1 955  ? 187.989 147.231 106.281 1.00 50.97  ? 955  SER   C C     1 
ATOM   5895 O O     . SER   A 1 955  ? 189.064 147.291 105.683 1.00 51.98  ? 955  SER   C O     1 
ATOM   5896 C CB    . SER   A 1 955  ? 186.235 148.026 104.718 1.00 54.05  ? 955  SER   C CB    1 
ATOM   5897 O OG    . SER   A 1 955  ? 186.035 149.158 105.521 1.00 52.21  ? 955  SER   C OG    1 
ATOM   5898 N N     . HIS   A 1 956  ? 187.886 147.454 107.582 1.00 52.48  ? 956  HIS   C N     1 
ATOM   5899 C CA    . HIS   A 1 956  ? 189.029 147.852 108.393 1.00 54.41  ? 956  HIS   C CA    1 
ATOM   5900 C C     . HIS   A 1 956  ? 190.059 146.735 108.511 1.00 52.86  ? 956  HIS   C C     1 
ATOM   5901 O O     . HIS   A 1 956  ? 191.206 146.974 108.888 1.00 53.56  ? 956  HIS   C O     1 
ATOM   5902 C CB    . HIS   A 1 956  ? 188.574 148.268 109.795 1.00 54.34  ? 956  HIS   C CB    1 
ATOM   5903 C CG    . HIS   A 1 956  ? 187.819 149.559 109.829 1.00 57.31  ? 956  HIS   C CG    1 
ATOM   5904 N ND1   . HIS   A 1 956  ? 188.423 150.780 109.616 1.00 61.23  ? 956  HIS   C ND1   1 
ATOM   5905 C CD2   . HIS   A 1 956  ? 186.509 149.820 110.050 1.00 60.19  ? 956  HIS   C CD2   1 
ATOM   5906 C CE1   . HIS   A 1 956  ? 187.517 151.738 109.708 1.00 66.66  ? 956  HIS   C CE1   1 
ATOM   5907 N NE2   . HIS   A 1 956  ? 186.349 151.182 109.970 1.00 63.69  ? 956  HIS   C NE2   1 
ATOM   5908 N N     . CYS   A 1 957  ? 189.653 145.508 108.197 1.00 50.62  ? 957  CYS   C N     1 
ATOM   5909 C CA    . CYS   A 1 957  ? 190.552 144.365 108.303 1.00 49.66  ? 957  CYS   C CA    1 
ATOM   5910 C C     . CYS   A 1 957  ? 191.270 144.079 106.988 1.00 53.47  ? 957  CYS   C C     1 
ATOM   5911 O O     . CYS   A 1 957  ? 192.089 143.162 106.910 1.00 54.46  ? 957  CYS   C O     1 
ATOM   5912 C CB    . CYS   A 1 957  ? 189.789 143.112 108.726 1.00 45.93  ? 957  CYS   C CB    1 
ATOM   5913 S SG    . CYS   A 1 957  ? 188.723 142.416 107.449 1.00 43.34  ? 957  CYS   C SG    1 
ATOM   5914 N N     . CYS   A 1 958  ? 190.948 144.841 105.943 1.00 52.32  ? 958  CYS   C N     1 
ATOM   5915 C CA    . CYS   A 1 958  ? 191.509 144.573 104.624 1.00 52.03  ? 958  CYS   C CA    1 
ATOM   5916 C C     . CYS   A 1 958  ? 193.003 144.836 104.552 1.00 52.88  ? 958  CYS   C C     1 
ATOM   5917 O O     . CYS   A 1 958  ? 193.706 144.198 103.774 1.00 54.56  ? 958  CYS   C O     1 
ATOM   5918 C CB    . CYS   A 1 958  ? 190.792 145.387 103.563 1.00 57.66  ? 958  CYS   C CB    1 
ATOM   5919 S SG    . CYS   A 1 958  ? 189.117 144.825 103.287 1.00 63.21  ? 958  CYS   C SG    1 
ATOM   5920 N N     . TRP   A 1 959  ? 193.504 145.754 105.368 1.00 59.90  ? 959  TRP   C N     1 
ATOM   5921 C CA    . TRP   A 1 959  ? 194.932 146.033 105.368 1.00 62.08  ? 959  TRP   C CA    1 
ATOM   5922 C C     . TRP   A 1 959  ? 195.715 144.822 105.857 1.00 59.13  ? 959  TRP   C C     1 
ATOM   5923 O O     . TRP   A 1 959  ? 196.820 144.543 105.382 1.00 65.28  ? 959  TRP   C O     1 
ATOM   5924 C CB    . TRP   A 1 959  ? 195.242 147.225 106.267 1.00 62.96  ? 959  TRP   C CB    1 
ATOM   5925 C CG    . TRP   A 1 959  ? 194.859 148.533 105.678 1.00 69.53  ? 959  TRP   C CG    1 
ATOM   5926 C CD1   . TRP   A 1 959  ? 193.818 149.328 106.053 1.00 71.69  ? 959  TRP   C CD1   1 
ATOM   5927 C CD2   . TRP   A 1 959  ? 195.518 149.220 104.594 1.00 75.05  ? 959  TRP   C CD2   1 
ATOM   5928 N NE1   . TRP   A 1 959  ? 193.785 150.458 105.279 1.00 73.98  ? 959  TRP   C NE1   1 
ATOM   5929 C CE2   . TRP   A 1 959  ? 194.823 150.413 104.385 1.00 77.09  ? 959  TRP   C CE2   1 
ATOM   5930 C CE3   . TRP   A 1 959  ? 196.634 148.928 103.803 1.00 74.25  ? 959  TRP   C CE3   1 
ATOM   5931 C CZ2   . TRP   A 1 959  ? 195.196 151.315 103.406 1.00 81.33  ? 959  TRP   C CZ2   1 
ATOM   5932 C CZ3   . TRP   A 1 959  ? 197.009 149.833 102.821 1.00 81.53  ? 959  TRP   C CZ3   1 
ATOM   5933 C CH2   . TRP   A 1 959  ? 196.310 150.998 102.631 1.00 82.69  ? 959  TRP   C CH2   1 
ATOM   5934 N N     . ASP   A 1 960  ? 195.128 144.089 106.796 1.00 62.82  ? 960  ASP   C N     1 
ATOM   5935 C CA    . ASP   A 1 960  ? 195.792 142.938 107.376 1.00 54.61  ? 960  ASP   C CA    1 
ATOM   5936 C C     . ASP   A 1 960  ? 195.611 141.719 106.481 1.00 55.14  ? 960  ASP   C C     1 
ATOM   5937 O O     . ASP   A 1 960  ? 196.530 140.913 106.319 1.00 55.83  ? 960  ASP   C O     1 
ATOM   5938 C CB    . ASP   A 1 960  ? 195.229 142.675 108.768 1.00 53.47  ? 960  ASP   C CB    1 
ATOM   5939 C CG    . ASP   A 1 960  ? 195.503 143.821 109.731 1.00 55.95  ? 960  ASP   C CG    1 
ATOM   5940 O OD1   . ASP   A 1 960  ? 196.630 143.997 110.121 1.00 57.13  ? 960  ASP   C OD1   1 
ATOM   5941 O OD2   . ASP   A 1 960  ? 194.573 144.523 110.062 1.00 54.61  ? 960  ASP   C OD2   1 
ATOM   5942 N N     . LEU   A 1 961  ? 194.443 141.610 105.853 1.00 52.49  ? 961  LEU   C N     1 
ATOM   5943 C CA    . LEU   A 1 961  ? 194.212 140.520 104.920 1.00 49.20  ? 961  LEU   C CA    1 
ATOM   5944 C C     . LEU   A 1 961  ? 195.089 140.723 103.688 1.00 54.83  ? 961  LEU   C C     1 
ATOM   5945 O O     . LEU   A 1 961  ? 195.627 139.765 103.133 1.00 54.13  ? 961  LEU   C O     1 
ATOM   5946 C CB    . LEU   A 1 961  ? 192.732 140.452 104.526 1.00 49.85  ? 961  LEU   C CB    1 
ATOM   5947 C CG    . LEU   A 1 961  ? 191.736 140.026 105.639 1.00 43.11  ? 961  LEU   C CG    1 
ATOM   5948 C CD1   . LEU   A 1 961  ? 190.322 140.224 105.137 1.00 40.10  ? 961  LEU   C CD1   1 
ATOM   5949 C CD2   . LEU   A 1 961  ? 191.961 138.566 106.024 1.00 38.23  ? 961  LEU   C CD2   1 
ATOM   5950 N N     . SER   A 1 962  ? 195.261 141.983 103.287 1.00 54.87  ? 962  SER   C N     1 
ATOM   5951 C CA    . SER   A 1 962  ? 196.114 142.330 102.158 1.00 58.19  ? 962  SER   C CA    1 
ATOM   5952 C C     . SER   A 1 962  ? 197.544 141.910 102.440 1.00 57.33  ? 962  SER   C C     1 
ATOM   5953 O O     . SER   A 1 962  ? 198.229 141.360 101.575 1.00 59.57  ? 962  SER   C O     1 
ATOM   5954 C CB    . SER   A 1 962  ? 196.055 143.820 101.893 1.00 58.93  ? 962  SER   C CB    1 
ATOM   5955 O OG    . SER   A 1 962  ? 196.872 144.169 100.819 1.00 64.54  ? 962  SER   C OG    1 
ATOM   5956 N N     . THR   A 1 963  ? 197.987 142.151 103.669 1.00 55.53  ? 963  THR   C N     1 
ATOM   5957 C CA    . THR   A 1 963  ? 199.324 141.764 104.075 1.00 56.44  ? 963  THR   C CA    1 
ATOM   5958 C C     . THR   A 1 963  ? 199.506 140.259 103.928 1.00 56.24  ? 963  THR   C C     1 
ATOM   5959 O O     . THR   A 1 963  ? 200.517 139.803 103.395 1.00 57.70  ? 963  THR   C O     1 
ATOM   5960 C CB    . THR   A 1 963  ? 199.609 142.186 105.525 1.00 60.56  ? 963  THR   C CB    1 
ATOM   5961 O OG1   . THR   A 1 963  ? 199.497 143.614 105.638 1.00 62.46  ? 963  THR   C OG1   1 
ATOM   5962 C CG2   . THR   A 1 963  ? 201.015 141.768 105.918 1.00 61.91  ? 963  THR   C CG2   1 
ATOM   5963 N N     . LEU   A 1 964  ? 198.516 139.479 104.362 1.00 55.98  ? 964  LEU   C N     1 
ATOM   5964 C CA    . LEU   A 1 964  ? 198.624 138.027 104.245 1.00 54.80  ? 964  LEU   C CA    1 
ATOM   5965 C C     . LEU   A 1 964  ? 198.800 137.608 102.795 1.00 56.26  ? 964  LEU   C C     1 
ATOM   5966 O O     . LEU   A 1 964  ? 199.614 136.739 102.486 1.00 55.58  ? 964  LEU   C O     1 
ATOM   5967 C CB    . LEU   A 1 964  ? 197.354 137.332 104.767 1.00 49.80  ? 964  LEU   C CB    1 
ATOM   5968 C CG    . LEU   A 1 964  ? 197.067 137.411 106.262 1.00 49.55  ? 964  LEU   C CG    1 
ATOM   5969 C CD1   . LEU   A 1 964  ? 195.672 136.861 106.519 1.00 43.93  ? 964  LEU   C CD1   1 
ATOM   5970 C CD2   . LEU   A 1 964  ? 198.092 136.615 107.027 1.00 47.19  ? 964  LEU   C CD2   1 
ATOM   5971 N N     . LEU   A 1 965  ? 198.061 138.250 101.899 1.00 54.94  ? 965  LEU   C N     1 
ATOM   5972 C CA    . LEU   A 1 965  ? 198.072 137.861 100.497 1.00 51.83  ? 965  LEU   C CA    1 
ATOM   5973 C C     . LEU   A 1 965  ? 199.452 137.978 99.858  1.00 56.04  ? 965  LEU   C C     1 
ATOM   5974 O O     . LEU   A 1 965  ? 199.802 137.164 99.003  1.00 56.19  ? 965  LEU   C O     1 
ATOM   5975 C CB    . LEU   A 1 965  ? 197.073 138.714 99.701  1.00 51.73  ? 965  LEU   C CB    1 
ATOM   5976 C CG    . LEU   A 1 965  ? 195.571 138.520 100.045 1.00 52.24  ? 965  LEU   C CG    1 
ATOM   5977 C CD1   . LEU   A 1 965  ? 194.744 139.558 99.281  1.00 59.93  ? 965  LEU   C CD1   1 
ATOM   5978 C CD2   . LEU   A 1 965  ? 195.133 137.102 99.699  1.00 50.74  ? 965  LEU   C CD2   1 
ATOM   5979 N N     . THR   A 1 966  ? 200.241 138.975 100.255 1.00 56.95  ? 966  THR   C N     1 
ATOM   5980 C CA    . THR   A 1 966  ? 201.561 139.129 99.644  1.00 58.98  ? 966  THR   C CA    1 
ATOM   5981 C C     . THR   A 1 966  ? 202.715 138.671 100.537 1.00 59.15  ? 966  THR   C C     1 
ATOM   5982 O O     . THR   A 1 966  ? 203.792 138.346 100.034 1.00 59.11  ? 966  THR   C O     1 
ATOM   5983 C CB    . THR   A 1 966  ? 201.807 140.587 99.223  1.00 59.83  ? 966  THR   C CB    1 
ATOM   5984 O OG1   . THR   A 1 966  ? 201.772 141.438 100.378 1.00 59.69  ? 966  THR   C OG1   1 
ATOM   5985 C CG2   . THR   A 1 966  ? 200.742 141.026 98.242  1.00 65.15  ? 966  THR   C CG2   1 
ATOM   5986 N N     . SER   A 1 967  ? 202.507 138.639 101.849 1.00 61.64  ? 967  SER   C N     1 
ATOM   5987 C CA    . SER   A 1 967  ? 203.583 138.255 102.760 1.00 59.58  ? 967  SER   C CA    1 
ATOM   5988 C C     . SER   A 1 967  ? 203.633 136.753 103.025 1.00 60.18  ? 967  SER   C C     1 
ATOM   5989 O O     . SER   A 1 967  ? 204.706 136.204 103.287 1.00 59.21  ? 967  SER   C O     1 
ATOM   5990 C CB    . SER   A 1 967  ? 203.445 138.994 104.073 1.00 59.20  ? 967  SER   C CB    1 
ATOM   5991 O OG    . SER   A 1 967  ? 203.647 140.372 103.904 1.00 62.23  ? 967  SER   C OG    1 
ATOM   5992 N N     . SER   A 1 968  ? 202.481 136.086 102.967 1.00 60.08  ? 968  SER   C N     1 
ATOM   5993 C CA    . SER   A 1 968  ? 202.429 134.656 103.236 1.00 55.62  ? 968  SER   C CA    1 
ATOM   5994 C C     . SER   A 1 968  ? 203.112 133.883 102.129 1.00 54.41  ? 968  SER   C C     1 
ATOM   5995 O O     . SER   A 1 968  ? 203.001 134.229 100.955 1.00 54.57  ? 968  SER   C O     1 
ATOM   5996 C CB    . SER   A 1 968  ? 200.998 134.186 103.390 1.00 50.12  ? 968  SER   C CB    1 
ATOM   5997 O OG    . SER   A 1 968  ? 200.941 132.795 103.566 1.00 45.78  ? 968  SER   C OG    1 
ATOM   5998 N N     . GLN   A 1 969  ? 203.812 132.823 102.502 1.00 53.85  ? 969  GLN   C N     1 
ATOM   5999 C CA    . GLN   A 1 969  ? 204.453 131.971 101.514 1.00 53.76  ? 969  GLN   C CA    1 
ATOM   6000 C C     . GLN   A 1 969  ? 203.765 130.613 101.414 1.00 51.49  ? 969  GLN   C C     1 
ATOM   6001 O O     . GLN   A 1 969  ? 203.978 129.871 100.456 1.00 51.07  ? 969  GLN   C O     1 
ATOM   6002 C CB    . GLN   A 1 969  ? 205.930 131.799 101.857 1.00 55.48  ? 969  GLN   C CB    1 
ATOM   6003 C CG    . GLN   A 1 969  ? 206.674 133.119 101.995 1.00 59.39  ? 969  GLN   C CG    1 
ATOM   6004 C CD    . GLN   A 1 969  ? 206.630 133.949 100.730 1.00 61.22  ? 969  GLN   C CD    1 
ATOM   6005 O OE1   . GLN   A 1 969  ? 207.035 133.491 99.657  1.00 62.79  ? 969  GLN   C OE1   1 
ATOM   6006 N NE2   . GLN   A 1 969  ? 206.131 135.176 100.846 1.00 62.29  ? 969  GLN   C NE2   1 
ATOM   6007 N N     . SER   A 1 970  ? 202.979 130.272 102.438 1.00 47.95  ? 970  SER   C N     1 
ATOM   6008 C CA    . SER   A 1 970  ? 202.378 128.949 102.552 1.00 39.61  ? 970  SER   C CA    1 
ATOM   6009 C C     . SER   A 1 970  ? 200.858 128.916 102.368 1.00 35.06  ? 970  SER   C C     1 
ATOM   6010 O O     . SER   A 1 970  ? 200.288 127.843 102.167 1.00 32.80  ? 970  SER   C O     1 
ATOM   6011 C CB    . SER   A 1 970  ? 202.749 128.367 103.904 1.00 42.76  ? 970  SER   C CB    1 
ATOM   6012 O OG    . SER   A 1 970  ? 202.331 129.213 104.948 1.00 42.76  ? 970  SER   C OG    1 
ATOM   6013 N N     . LEU   A 1 971  ? 200.199 130.072 102.428 1.00 34.46  ? 971  LEU   C N     1 
ATOM   6014 C CA    . LEU   A 1 971  ? 198.741 130.109 102.289 1.00 29.54  ? 971  LEU   C CA    1 
ATOM   6015 C C     . LEU   A 1 971  ? 198.359 129.910 100.825 1.00 33.82  ? 971  LEU   C C     1 
ATOM   6016 O O     . LEU   A 1 971  ? 198.943 130.536 99.944  1.00 39.57  ? 971  LEU   C O     1 
ATOM   6017 C CB    . LEU   A 1 971  ? 198.192 131.451 102.804 1.00 30.63  ? 971  LEU   C CB    1 
ATOM   6018 C CG    . LEU   A 1 971  ? 196.650 131.610 102.872 1.00 25.85  ? 971  LEU   C CG    1 
ATOM   6019 C CD1   . LEU   A 1 971  ? 196.085 130.707 103.966 1.00 19.12  ? 971  LEU   C CD1   1 
ATOM   6020 C CD2   . LEU   A 1 971  ? 196.305 133.070 103.151 1.00 31.86  ? 971  LEU   C CD2   1 
ATOM   6021 N N     . ARG   A 1 972  ? 197.399 129.028 100.556 1.00 29.17  ? 972  ARG   C N     1 
ATOM   6022 C CA    . ARG   A 1 972  ? 196.992 128.766 99.180  1.00 28.28  ? 972  ARG   C CA    1 
ATOM   6023 C C     . ARG   A 1 972  ? 195.562 129.203 98.913  1.00 31.64  ? 972  ARG   C C     1 
ATOM   6024 O O     . ARG   A 1 972  ? 195.249 129.665 97.812  1.00 42.21  ? 972  ARG   C O     1 
ATOM   6025 C CB    . ARG   A 1 972  ? 197.149 127.294 98.845  1.00 27.23  ? 972  ARG   C CB    1 
ATOM   6026 C CG    . ARG   A 1 972  ? 198.578 126.765 98.943  1.00 29.50  ? 972  ARG   C CG    1 
ATOM   6027 C CD    . ARG   A 1 972  ? 199.504 127.481 98.021  1.00 36.69  ? 972  ARG   C CD    1 
ATOM   6028 N NE    . ARG   A 1 972  ? 200.818 126.875 97.994  1.00 38.20  ? 972  ARG   C NE    1 
ATOM   6029 C CZ    . ARG   A 1 972  ? 201.914 127.440 97.447  1.00 48.08  ? 972  ARG   C CZ    1 
ATOM   6030 N NH1   . ARG   A 1 972  ? 201.845 128.634 96.889  1.00 51.30  ? 972  ARG   C NH1   1 
ATOM   6031 N NH2   . ARG   A 1 972  ? 203.067 126.791 97.471  1.00 50.78  ? 972  ARG   C NH2   1 
ATOM   6032 N N     . LYS   A 1 973  ? 194.701 129.061 99.917  1.00 24.04  ? 973  LYS   C N     1 
ATOM   6033 C CA    . LYS   A 1 973  ? 193.295 129.432 99.792  1.00 21.77  ? 973  LYS   C CA    1 
ATOM   6034 C C     . LYS   A 1 973  ? 192.915 130.411 100.896 1.00 20.68  ? 973  LYS   C C     1 
ATOM   6035 O O     . LYS   A 1 973  ? 193.407 130.304 102.019 1.00 26.24  ? 973  LYS   C O     1 
ATOM   6036 C CB    . LYS   A 1 973  ? 192.410 128.186 99.875  1.00 24.40  ? 973  LYS   C CB    1 
ATOM   6037 C CG    . LYS   A 1 973  ? 190.923 128.418 99.597  1.00 27.42  ? 973  LYS   C CG    1 
ATOM   6038 C CD    . LYS   A 1 973  ? 190.091 127.144 99.807  1.00 29.98  ? 973  LYS   C CD    1 
ATOM   6039 C CE    . LYS   A 1 973  ? 190.304 126.120 98.704  1.00 36.55  ? 973  LYS   C CE    1 
ATOM   6040 N NZ    . LYS   A 1 973  ? 189.452 124.912 98.903  1.00 40.79  ? 973  LYS   C NZ    1 
ATOM   6041 N N     . LEU   A 1 974  ? 192.033 131.353 100.581 1.00 20.89  ? 974  LEU   C N     1 
ATOM   6042 C CA    . LEU   A 1 974  ? 191.515 132.283 101.577 1.00 18.49  ? 974  LEU   C CA    1 
ATOM   6043 C C     . LEU   A 1 974  ? 190.058 132.568 101.281 1.00 19.50  ? 974  LEU   C C     1 
ATOM   6044 O O     . LEU   A 1 974  ? 189.728 133.468 100.511 1.00 24.38  ? 974  LEU   C O     1 
ATOM   6045 C CB    . LEU   A 1 974  ? 192.318 133.591 101.574 1.00 22.69  ? 974  LEU   C CB    1 
ATOM   6046 C CG    . LEU   A 1 974  ? 191.916 134.645 102.638 1.00 19.15  ? 974  LEU   C CG    1 
ATOM   6047 C CD1   . LEU   A 1 974  ? 192.182 134.109 104.040 1.00 18.73  ? 974  LEU   C CD1   1 
ATOM   6048 C CD2   . LEU   A 1 974  ? 192.702 135.918 102.396 1.00 27.35  ? 974  LEU   C CD2   1 
ATOM   6049 N N     . SER   A 1 975  ? 189.183 131.770 101.866 1.00 15.49  ? 975  SER   C N     1 
ATOM   6050 C CA    . SER   A 1 975  ? 187.776 131.815 101.508 1.00 16.60  ? 975  SER   C CA    1 
ATOM   6051 C C     . SER   A 1 975  ? 187.007 132.863 102.283 1.00 16.37  ? 975  SER   C C     1 
ATOM   6052 O O     . SER   A 1 975  ? 186.224 132.534 103.173 1.00 17.84  ? 975  SER   C O     1 
ATOM   6053 C CB    . SER   A 1 975  ? 187.133 130.458 101.712 1.00 18.42  ? 975  SER   C CB    1 
ATOM   6054 O OG    . SER   A 1 975  ? 187.640 129.512 100.810 1.00 23.13  ? 975  SER   C OG    1 
ATOM   6055 N N     . LEU   A 1 976  ? 187.215 134.127 101.937 1.00 18.72  ? 976  LEU   C N     1 
ATOM   6056 C CA    . LEU   A 1 976  ? 186.448 135.187 102.576 1.00 16.24  ? 976  LEU   C CA    1 
ATOM   6057 C C     . LEU   A 1 976  ? 185.014 135.036 102.093 1.00 19.60  ? 976  LEU   C C     1 
ATOM   6058 O O     . LEU   A 1 976  ? 184.775 134.937 100.893 1.00 27.39  ? 976  LEU   C O     1 
ATOM   6059 C CB    . LEU   A 1 976  ? 186.994 136.568 102.188 1.00 17.06  ? 976  LEU   C CB    1 
ATOM   6060 C CG    . LEU   A 1 976  ? 188.483 136.823 102.498 1.00 20.31  ? 976  LEU   C CG    1 
ATOM   6061 C CD1   . LEU   A 1 976  ? 188.872 138.186 101.986 1.00 31.92  ? 976  LEU   C CD1   1 
ATOM   6062 C CD2   . LEU   A 1 976  ? 188.734 136.720 103.986 1.00 21.05  ? 976  LEU   C CD2   1 
ATOM   6063 N N     . GLY   A 1 977  ? 184.063 134.981 103.014 1.00 21.33  ? 977  GLY   C N     1 
ATOM   6064 C CA    . GLY   A 1 977  ? 182.673 134.721 102.635 1.00 20.33  ? 977  GLY   C CA    1 
ATOM   6065 C C     . GLY   A 1 977  ? 181.736 135.903 102.837 1.00 20.22  ? 977  GLY   C C     1 
ATOM   6066 O O     . GLY   A 1 977  ? 182.057 137.041 102.499 1.00 24.96  ? 977  GLY   C O     1 
ATOM   6067 N N     . ASN   A 1 978  ? 180.554 135.608 103.366 1.00 21.21  ? 978  ASN   C N     1 
ATOM   6068 C CA    . ASN   A 1 978  ? 179.473 136.579 103.469 1.00 21.87  ? 978  ASN   C CA    1 
ATOM   6069 C C     . ASN   A 1 978  ? 179.684 137.579 104.593 1.00 23.70  ? 978  ASN   C C     1 
ATOM   6070 O O     . ASN   A 1 978  ? 179.161 137.414 105.695 1.00 27.01  ? 978  ASN   C O     1 
ATOM   6071 C CB    . ASN   A 1 978  ? 178.160 135.848 103.682 1.00 22.79  ? 978  ASN   C CB    1 
ATOM   6072 C CG    . ASN   A 1 978  ? 176.959 136.741 103.612 1.00 32.84  ? 978  ASN   C CG    1 
ATOM   6073 O OD1   . ASN   A 1 978  ? 177.072 137.972 103.618 1.00 37.72  ? 978  ASN   C OD1   1 
ATOM   6074 N ND2   . ASN   A 1 978  ? 175.798 136.139 103.547 1.00 36.09  ? 978  ASN   C ND2   1 
ATOM   6075 N N     . ASN   A 1 979  ? 180.425 138.636 104.298 1.00 24.42  ? 979  ASN   C N     1 
ATOM   6076 C CA    . ASN   A 1 979  ? 180.679 139.690 105.267 1.00 27.06  ? 979  ASN   C CA    1 
ATOM   6077 C C     . ASN   A 1 979  ? 180.818 141.029 104.554 1.00 34.68  ? 979  ASN   C C     1 
ATOM   6078 O O     . ASN   A 1 979  ? 180.936 141.078 103.329 1.00 36.97  ? 979  ASN   C O     1 
ATOM   6079 C CB    . ASN   A 1 979  ? 181.909 139.358 106.087 1.00 24.15  ? 979  ASN   C CB    1 
ATOM   6080 C CG    . ASN   A 1 979  ? 183.139 139.232 105.249 1.00 29.73  ? 979  ASN   C CG    1 
ATOM   6081 O OD1   . ASN   A 1 979  ? 183.685 140.235 104.788 1.00 37.76  ? 979  ASN   C OD1   1 
ATOM   6082 N ND2   . ASN   A 1 979  ? 183.588 138.026 105.036 1.00 24.81  ? 979  ASN   C ND2   1 
ATOM   6083 N N     . ASP   A 1 980  ? 180.815 142.122 105.309 1.00 36.72  ? 980  ASP   C N     1 
ATOM   6084 C CA    . ASP   A 1 980  ? 180.924 143.439 104.693 1.00 40.88  ? 980  ASP   C CA    1 
ATOM   6085 C C     . ASP   A 1 980  ? 182.379 143.814 104.469 1.00 42.87  ? 980  ASP   C C     1 
ATOM   6086 O O     . ASP   A 1 980  ? 182.898 144.752 105.073 1.00 45.71  ? 980  ASP   C O     1 
ATOM   6087 C CB    . ASP   A 1 980  ? 180.239 144.500 105.553 1.00 49.40  ? 980  ASP   C CB    1 
ATOM   6088 C CG    . ASP   A 1 980  ? 180.102 145.835 104.835 1.00 57.72  ? 980  ASP   C CG    1 
ATOM   6089 O OD1   . ASP   A 1 980  ? 180.227 145.854 103.630 1.00 53.40  ? 980  ASP   C OD1   1 
ATOM   6090 O OD2   . ASP   A 1 980  ? 179.869 146.823 105.493 1.00 57.76  ? 980  ASP   C OD2   1 
ATOM   6091 N N     . LEU   A 1 981  ? 183.021 143.082 103.572 1.00 41.16  ? 981  LEU   C N     1 
ATOM   6092 C CA    . LEU   A 1 981  ? 184.429 143.271 103.269 1.00 43.37  ? 981  LEU   C CA    1 
ATOM   6093 C C     . LEU   A 1 981  ? 184.669 144.638 102.641 1.00 49.45  ? 981  LEU   C C     1 
ATOM   6094 O O     . LEU   A 1 981  ? 185.670 145.297 102.921 1.00 51.91  ? 981  LEU   C O     1 
ATOM   6095 C CB    . LEU   A 1 981  ? 184.894 142.169 102.311 1.00 38.95  ? 981  LEU   C CB    1 
ATOM   6096 C CG    . LEU   A 1 981  ? 186.383 142.123 101.967 1.00 42.33  ? 981  LEU   C CG    1 
ATOM   6097 C CD1   . LEU   A 1 981  ? 187.212 141.855 103.228 1.00 36.89  ? 981  LEU   C CD1   1 
ATOM   6098 C CD2   . LEU   A 1 981  ? 186.592 141.044 100.937 1.00 45.95  ? 981  LEU   C CD2   1 
ATOM   6099 N N     . GLY   A 1 982  ? 183.748 145.055 101.779 1.00 50.22  ? 982  GLY   C N     1 
ATOM   6100 C CA    . GLY   A 1 982  ? 183.840 146.342 101.103 1.00 60.49  ? 982  GLY   C CA    1 
ATOM   6101 C C     . GLY   A 1 982  ? 184.378 146.215 99.682  1.00 68.04  ? 982  GLY   C C     1 
ATOM   6102 O O     . GLY   A 1 982  ? 185.178 145.325 99.379  1.00 68.74  ? 982  GLY   C O     1 
ATOM   6103 N N     . ASP   A 1 983  ? 183.946 147.126 98.815  1.00 72.40  ? 983  ASP   C N     1 
ATOM   6104 C CA    . ASP   A 1 983  ? 184.382 147.149 97.426  1.00 77.47  ? 983  ASP   C CA    1 
ATOM   6105 C C     . ASP   A 1 983  ? 185.803 147.674 97.329  1.00 85.96  ? 983  ASP   C C     1 
ATOM   6106 O O     . ASP   A 1 983  ? 186.614 147.169 96.551  1.00 70.90  ? 983  ASP   C O     1 
ATOM   6107 C CB    . ASP   A 1 983  ? 183.440 148.029 96.616  1.00 73.21  ? 983  ASP   C CB    1 
ATOM   6108 C CG    . ASP   A 1 983  ? 183.286 149.396 97.259  1.00 80.93  ? 983  ASP   C CG    1 
ATOM   6109 O OD1   . ASP   A 1 983  ? 183.539 149.494 98.451  1.00 79.05  ? 983  ASP   C OD1   1 
ATOM   6110 O OD2   . ASP   A 1 983  ? 182.917 150.323 96.580  1.00 87.23  ? 983  ASP   C OD2   1 
ATOM   6111 N N     . LEU   A 1 984  ? 186.110 148.666 98.157  1.00 74.20  ? 984  LEU   C N     1 
ATOM   6112 C CA    . LEU   A 1 984  ? 187.447 149.243 98.198  1.00 75.24  ? 984  LEU   C CA    1 
ATOM   6113 C C     . LEU   A 1 984  ? 188.444 148.206 98.692  1.00 79.17  ? 984  LEU   C C     1 
ATOM   6114 O O     . LEU   A 1 984  ? 189.583 148.148 98.224  1.00 80.46  ? 984  LEU   C O     1 
ATOM   6115 C CB    . LEU   A 1 984  ? 187.475 150.466 99.120  1.00 80.30  ? 984  LEU   C CB    1 
ATOM   6116 C CG    . LEU   A 1 984  ? 186.672 151.696 98.645  1.00 85.34  ? 984  LEU   C CG    1 
ATOM   6117 C CD1   . LEU   A 1 984  ? 186.638 152.727 99.764  1.00 84.28  ? 984  LEU   C CD1   1 
ATOM   6118 C CD2   . LEU   A 1 984  ? 187.314 152.288 97.392  1.00 79.93  ? 984  LEU   C CD2   1 
ATOM   6119 N N     . GLY   A 1 985  ? 187.996 147.370 99.623  1.00 70.80  ? 985  GLY   C N     1 
ATOM   6120 C CA    . GLY   A 1 985  ? 188.808 146.287 100.159 1.00 72.85  ? 985  GLY   C CA    1 
ATOM   6121 C C     . GLY   A 1 985  ? 189.221 145.342 99.044  1.00 72.38  ? 985  GLY   C C     1 
ATOM   6122 O O     . GLY   A 1 985  ? 190.402 145.034 98.879  1.00 75.77  ? 985  GLY   C O     1 
ATOM   6123 N N     . VAL   A 1 986  ? 188.245 144.906 98.261  1.00 71.56  ? 986  VAL   C N     1 
ATOM   6124 C CA    . VAL   A 1 986  ? 188.513 144.016 97.147  1.00 72.35  ? 986  VAL   C CA    1 
ATOM   6125 C C     . VAL   A 1 986  ? 189.419 144.646 96.103  1.00 77.00  ? 986  VAL   C C     1 
ATOM   6126 O O     . VAL   A 1 986  ? 190.291 143.971 95.553  1.00 78.53  ? 986  VAL   C O     1 
ATOM   6127 C CB    . VAL   A 1 986  ? 187.205 143.558 96.515  1.00 73.11  ? 986  VAL   C CB    1 
ATOM   6128 C CG1   . VAL   A 1 986  ? 187.469 142.845 95.205  1.00 80.26  ? 986  VAL   C CG1   1 
ATOM   6129 C CG2   . VAL   A 1 986  ? 186.532 142.634 97.483  1.00 67.22  ? 986  VAL   C CG2   1 
ATOM   6130 N N     . MET   A 1 987  ? 189.216 145.927 95.814  1.00 70.93  ? 987  MET   C N     1 
ATOM   6131 C CA    . MET   A 1 987  ? 190.085 146.601 94.859  1.00 75.60  ? 987  MET   C CA    1 
ATOM   6132 C C     . MET   A 1 987  ? 191.530 146.577 95.351  1.00 106.85 ? 987  MET   C C     1 
ATOM   6133 O O     . MET   A 1 987  ? 192.455 146.372 94.562  1.00 82.25  ? 987  MET   C O     1 
ATOM   6134 C CB    . MET   A 1 987  ? 189.619 148.034 94.624  1.00 84.56  ? 987  MET   C CB    1 
ATOM   6135 C CG    . MET   A 1 987  ? 188.324 148.153 93.832  1.00 88.61  ? 987  MET   C CG    1 
ATOM   6136 S SD    . MET   A 1 987  ? 188.422 147.400 92.195  1.00 78.68  ? 987  MET   C SD    1 
ATOM   6137 C CE    . MET   A 1 987  ? 189.583 148.475 91.353  1.00 105.39 ? 987  MET   C CE    1 
ATOM   6138 N N     . MET   A 1 988  ? 191.721 146.750 96.661  1.00 83.01  ? 988  MET   C N     1 
ATOM   6139 C CA    . MET   A 1 988  ? 193.056 146.679 97.242  1.00 79.01  ? 988  MET   C CA    1 
ATOM   6140 C C     . MET   A 1 988  ? 193.664 145.314 96.959  1.00 79.73  ? 988  MET   C C     1 
ATOM   6141 O O     . MET   A 1 988  ? 194.807 145.215 96.509  1.00 87.05  ? 988  MET   C O     1 
ATOM   6142 C CB    . MET   A 1 988  ? 193.007 146.905 98.756  1.00 74.08  ? 988  MET   C CB    1 
ATOM   6143 C CG    . MET   A 1 988  ? 194.378 147.039 99.436  1.00 79.91  ? 988  MET   C CG    1 
ATOM   6144 S SD    . MET   A 1 988  ? 194.275 147.080 101.257 1.00 73.59  ? 988  MET   C SD    1 
ATOM   6145 C CE    . MET   A 1 988  ? 193.347 148.575 101.581 1.00 79.03  ? 988  MET   C CE    1 
ATOM   6146 N N     . PHE   A 1 989  ? 192.882 144.261 97.204  1.00 76.41  ? 989  PHE   C N     1 
ATOM   6147 C CA    . PHE   A 1 989  ? 193.351 142.899 96.993  1.00 76.59  ? 989  PHE   C CA    1 
ATOM   6148 C C     . PHE   A 1 989  ? 193.727 142.686 95.534  1.00 84.00  ? 989  PHE   C C     1 
ATOM   6149 O O     . PHE   A 1 989  ? 194.770 142.112 95.231  1.00 80.35  ? 989  PHE   C O     1 
ATOM   6150 C CB    . PHE   A 1 989  ? 192.280 141.879 97.384  1.00 74.23  ? 989  PHE   C CB    1 
ATOM   6151 C CG    . PHE   A 1 989  ? 191.913 141.859 98.854  1.00 68.08  ? 989  PHE   C CG    1 
ATOM   6152 C CD1   . PHE   A 1 989  ? 192.644 142.558 99.817  1.00 65.40  ? 989  PHE   C CD1   1 
ATOM   6153 C CD2   . PHE   A 1 989  ? 190.820 141.124 99.278  1.00 61.90  ? 989  PHE   C CD2   1 
ATOM   6154 C CE1   . PHE   A 1 989  ? 192.269 142.516 101.136 1.00 64.13  ? 989  PHE   C CE1   1 
ATOM   6155 C CE2   . PHE   A 1 989  ? 190.466 141.091 100.598 1.00 56.64  ? 989  PHE   C CE2   1 
ATOM   6156 C CZ    . PHE   A 1 989  ? 191.184 141.785 101.518 1.00 59.18  ? 989  PHE   C CZ    1 
ATOM   6157 N N     . CYS   A 1 990  ? 192.898 143.177 94.623  1.00 75.98  ? 990  CYS   C N     1 
ATOM   6158 C CA    . CYS   A 1 990  ? 193.155 142.985 93.203  1.00 77.68  ? 990  CYS   C CA    1 
ATOM   6159 C C     . CYS   A 1 990  ? 194.530 143.520 92.802  1.00 82.51  ? 990  CYS   C C     1 
ATOM   6160 O O     . CYS   A 1 990  ? 195.238 142.898 92.009  1.00 88.33  ? 990  CYS   C O     1 
ATOM   6161 C CB    . CYS   A 1 990  ? 192.082 143.684 92.370  1.00 90.34  ? 990  CYS   C CB    1 
ATOM   6162 S SG    . CYS   A 1 990  ? 190.436 142.953 92.528  1.00 93.41  ? 990  CYS   C SG    1 
ATOM   6163 N N     . GLU   A 1 991  ? 194.910 144.673 93.349  1.00 85.90  ? 991  GLU   C N     1 
ATOM   6164 C CA    . GLU   A 1 991  ? 196.197 145.278 93.021  1.00 86.78  ? 991  GLU   C CA    1 
ATOM   6165 C C     . GLU   A 1 991  ? 197.386 144.522 93.618  1.00 86.97  ? 991  GLU   C C     1 
ATOM   6166 O O     . GLU   A 1 991  ? 198.425 144.371 92.971  1.00 88.99  ? 991  GLU   C O     1 
ATOM   6167 C CB    . GLU   A 1 991  ? 196.236 146.728 93.507  1.00 97.77  ? 991  GLU   C CB    1 
ATOM   6168 C CG    . GLU   A 1 991  ? 195.303 147.675 92.764  1.00 96.83  ? 991  GLU   C CG    1 
ATOM   6169 C CD    . GLU   A 1 991  ? 195.336 149.079 93.316  1.00 97.23  ? 991  GLU   C CD    1 
ATOM   6170 O OE1   . GLU   A 1 991  ? 195.924 149.274 94.354  1.00 107.27 ? 991  GLU   C OE1   1 
ATOM   6171 O OE2   . GLU   A 1 991  ? 194.772 149.953 92.700  1.00 109.74 ? 991  GLU   C OE2   1 
ATOM   6172 N N     . VAL   A 1 992  ? 197.246 144.063 94.857  1.00 86.82  ? 992  VAL   C N     1 
ATOM   6173 C CA    . VAL   A 1 992  ? 198.357 143.397 95.536  1.00 86.02  ? 992  VAL   C CA    1 
ATOM   6174 C C     . VAL   A 1 992  ? 198.516 141.938 95.113  1.00 83.92  ? 992  VAL   C C     1 
ATOM   6175 O O     . VAL   A 1 992  ? 199.629 141.415 95.085  1.00 88.98  ? 992  VAL   C O     1 
ATOM   6176 C CB    . VAL   A 1 992  ? 198.204 143.497 97.069  1.00 83.75  ? 992  VAL   C CB    1 
ATOM   6177 C CG1   . VAL   A 1 992  ? 198.162 144.964 97.484  1.00 85.50  ? 992  VAL   C CG1   1 
ATOM   6178 C CG2   . VAL   A 1 992  ? 196.953 142.787 97.512  1.00 74.41  ? 992  VAL   C CG2   1 
ATOM   6179 N N     . LEU   A 1 993  ? 197.415 141.297 94.730  1.00 82.74  ? 993  LEU   C N     1 
ATOM   6180 C CA    . LEU   A 1 993  ? 197.436 139.900 94.298  1.00 85.08  ? 993  LEU   C CA    1 
ATOM   6181 C C     . LEU   A 1 993  ? 198.296 139.681 93.062  1.00 90.32  ? 993  LEU   C C     1 
ATOM   6182 O O     . LEU   A 1 993  ? 198.717 138.560 92.779  1.00 86.18  ? 993  LEU   C O     1 
ATOM   6183 C CB    . LEU   A 1 993  ? 196.011 139.414 94.005  1.00 87.02  ? 993  LEU   C CB    1 
ATOM   6184 C CG    . LEU   A 1 993  ? 195.115 139.164 95.222  1.00 76.36  ? 993  LEU   C CG    1 
ATOM   6185 C CD1   . LEU   A 1 993  ? 193.682 139.063 94.769  1.00 81.68  ? 993  LEU   C CD1   1 
ATOM   6186 C CD2   . LEU   A 1 993  ? 195.529 137.876 95.896  1.00 67.23  ? 993  LEU   C CD2   1 
ATOM   6187 N N     . LYS   A 1 994  ? 198.543 140.748 92.316  1.00 91.99  ? 994  LYS   C N     1 
ATOM   6188 C CA    . LYS   A 1 994  ? 199.333 140.659 91.099  1.00 93.68  ? 994  LYS   C CA    1 
ATOM   6189 C C     . LYS   A 1 994  ? 200.828 140.626 91.399  1.00 90.25  ? 994  LYS   C C     1 
ATOM   6190 O O     . LYS   A 1 994  ? 201.636 140.302 90.526  1.00 90.72  ? 994  LYS   C O     1 
ATOM   6191 C CB    . LYS   A 1 994  ? 199.014 141.835 90.180  1.00 93.62  ? 994  LYS   C CB    1 
ATOM   6192 C CG    . LYS   A 1 994  ? 197.608 141.815 89.613  1.00 96.05  ? 994  LYS   C CG    1 
ATOM   6193 C CD    . LYS   A 1 994  ? 197.356 143.021 88.732  1.00 94.39  ? 994  LYS   C CD    1 
ATOM   6194 C CE    . LYS   A 1 994  ? 195.963 142.987 88.131  1.00 98.80  ? 994  LYS   C CE    1 
ATOM   6195 N NZ    . LYS   A 1 994  ? 195.703 144.177 87.275  1.00 101.69 ? 994  LYS   C NZ    1 
ATOM   6196 N N     . GLN   A 1 995  ? 201.202 140.970 92.630  1.00 93.19  ? 995  GLN   C N     1 
ATOM   6197 C CA    . GLN   A 1 995  ? 202.607 141.049 93.004  1.00 92.54  ? 995  GLN   C CA    1 
ATOM   6198 C C     . GLN   A 1 995  ? 203.139 139.708 93.493  1.00 91.98  ? 995  GLN   C C     1 
ATOM   6199 O O     . GLN   A 1 995  ? 203.525 139.565 94.653  1.00 90.70  ? 995  GLN   C O     1 
ATOM   6200 C CB    . GLN   A 1 995  ? 202.805 142.110 94.087  1.00 97.81  ? 995  GLN   C CB    1 
ATOM   6201 C CG    . GLN   A 1 995  ? 202.368 143.502 93.670  1.00 93.30  ? 995  GLN   C CG    1 
ATOM   6202 C CD    . GLN   A 1 995  ? 203.173 144.024 92.506  1.00 95.69  ? 995  GLN   C CD    1 
ATOM   6203 O OE1   . GLN   A 1 995  ? 204.400 144.125 92.587  1.00 99.46  ? 995  GLN   C OE1   1 
ATOM   6204 N NE2   . GLN   A 1 995  ? 202.498 144.360 91.413  1.00 95.15  ? 995  GLN   C NE2   1 
ATOM   6205 N N     . GLN   A 1 996  ? 203.179 138.737 92.587  1.00 87.49  ? 996  GLN   C N     1 
ATOM   6206 C CA    . GLN   A 1 996  ? 203.684 137.396 92.884  1.00 89.26  ? 996  GLN   C CA    1 
ATOM   6207 C C     . GLN   A 1 996  ? 203.015 136.764 94.104  1.00 89.38  ? 996  GLN   C C     1 
ATOM   6208 O O     . GLN   A 1 996  ? 203.695 136.243 94.988  1.00 82.38  ? 996  GLN   C O     1 
ATOM   6209 C CB    . GLN   A 1 996  ? 205.202 137.433 93.105  1.00 97.29  ? 996  GLN   C CB    1 
ATOM   6210 C CG    . GLN   A 1 996  ? 206.008 137.845 91.888  1.00 98.05  ? 996  GLN   C CG    1 
ATOM   6211 C CD    . GLN   A 1 996  ? 205.997 136.787 90.809  1.00 100.51 ? 996  GLN   C CD    1 
ATOM   6212 O OE1   . GLN   A 1 996  ? 206.471 135.666 91.012  1.00 103.13 ? 996  GLN   C OE1   1 
ATOM   6213 N NE2   . GLN   A 1 996  ? 205.452 137.134 89.651  1.00 106.50 ? 996  GLN   C NE2   1 
ATOM   6214 N N     . SER   A 1 997  ? 201.688 136.798 94.145  1.00 80.68  ? 997  SER   C N     1 
ATOM   6215 C CA    . SER   A 1 997  ? 200.944 136.198 95.249  1.00 75.81  ? 997  SER   C CA    1 
ATOM   6216 C C     . SER   A 1 997  ? 201.092 134.683 95.262  1.00 65.24  ? 997  SER   C C     1 
ATOM   6217 O O     . SER   A 1 997  ? 201.177 134.049 94.210  1.00 69.82  ? 997  SER   C O     1 
ATOM   6218 C CB    . SER   A 1 997  ? 199.481 136.559 95.166  1.00 68.80  ? 997  SER   C CB    1 
ATOM   6219 O OG    . SER   A 1 997  ? 198.752 135.886 96.154  1.00 65.54  ? 997  SER   C OG    1 
ATOM   6220 N N     . CYS   A 1 998  ? 201.110 134.100 96.459  1.00 62.87  ? 998  CYS   C N     1 
ATOM   6221 C CA    . CYS   A 1 998  ? 201.213 132.651 96.609  1.00 60.47  ? 998  CYS   C CA    1 
ATOM   6222 C C     . CYS   A 1 998  ? 199.839 131.989 96.592  1.00 53.34  ? 998  CYS   C C     1 
ATOM   6223 O O     . CYS   A 1 998  ? 199.730 130.763 96.661  1.00 49.68  ? 998  CYS   C O     1 
ATOM   6224 C CB    . CYS   A 1 998  ? 201.917 132.285 97.915  1.00 58.35  ? 998  CYS   C CB    1 
ATOM   6225 S SG    . CYS   A 1 998  ? 200.942 132.611 99.399  1.00 63.95  ? 998  CYS   C SG    1 
ATOM   6226 N N     . LEU   A 1 999  ? 198.790 132.805 96.529  1.00 53.01  ? 999  LEU   C N     1 
ATOM   6227 C CA    . LEU   A 1 999  ? 197.431 132.285 96.534  1.00 48.99  ? 999  LEU   C CA    1 
ATOM   6228 C C     . LEU   A 1 999  ? 197.093 131.727 95.164  1.00 50.08  ? 999  LEU   C C     1 
ATOM   6229 O O     . LEU   A 1 999  ? 197.256 132.406 94.150  1.00 56.72  ? 999  LEU   C O     1 
ATOM   6230 C CB    . LEU   A 1 999  ? 196.423 133.389 96.890  1.00 47.16  ? 999  LEU   C CB    1 
ATOM   6231 C CG    . LEU   A 1 999  ? 196.227 133.757 98.396  1.00 45.51  ? 999  LEU   C CG    1 
ATOM   6232 C CD1   . LEU   A 1 999  ? 195.617 132.592 99.147  1.00 39.60  ? 999  LEU   C CD1   1 
ATOM   6233 C CD2   . LEU   A 1 999  ? 197.559 134.136 99.023  1.00 49.67  ? 999  LEU   C CD2   1 
ATOM   6234 N N     . LEU   A 1 1000 ? 196.647 130.479 95.138  1.00 46.04  ? 1000 LEU   C N     1 
ATOM   6235 C CA    . LEU   A 1 1000 ? 196.333 129.806 93.884  1.00 52.37  ? 1000 LEU   C CA    1 
ATOM   6236 C C     . LEU   A 1 1000 ? 194.886 129.350 93.856  1.00 51.82  ? 1000 LEU   C C     1 
ATOM   6237 O O     . LEU   A 1 1000 ? 194.331 129.051 92.797  1.00 59.93  ? 1000 LEU   C O     1 
ATOM   6238 C CB    . LEU   A 1 1000 ? 197.259 128.597 93.700  1.00 54.62  ? 1000 LEU   C CB    1 
ATOM   6239 C CG    . LEU   A 1 1000 ? 198.772 128.900 93.703  1.00 58.60  ? 1000 LEU   C CG    1 
ATOM   6240 C CD1   . LEU   A 1 1000 ? 199.539 127.590 93.675  1.00 58.74  ? 1000 LEU   C CD1   1 
ATOM   6241 C CD2   . LEU   A 1 1000 ? 199.133 129.764 92.495  1.00 67.67  ? 1000 LEU   C CD2   1 
ATOM   6242 N N     . GLN   A 1 1001 ? 194.289 129.245 95.031  1.00 44.66  ? 1001 GLN   C N     1 
ATOM   6243 C CA    . GLN   A 1 1001 ? 192.950 128.705 95.170  1.00 44.67  ? 1001 GLN   C CA    1 
ATOM   6244 C C     . GLN   A 1 1001 ? 191.948 129.800 95.500  1.00 35.64  ? 1001 GLN   C C     1 
ATOM   6245 O O     . GLN   A 1 1001 ? 192.299 130.977 95.574  1.00 36.27  ? 1001 GLN   C O     1 
ATOM   6246 C CB    . GLN   A 1 1001 ? 192.943 127.593 96.221  1.00 47.88  ? 1001 GLN   C CB    1 
ATOM   6247 C CG    . GLN   A 1 1001 ? 193.818 126.393 95.840  1.00 51.02  ? 1001 GLN   C CG    1 
ATOM   6248 C CD    . GLN   A 1 1001 ? 193.784 125.263 96.860  1.00 47.10  ? 1001 GLN   C CD    1 
ATOM   6249 O OE1   . GLN   A 1 1001 ? 193.783 125.490 98.072  1.00 38.98  ? 1001 GLN   C OE1   1 
ATOM   6250 N NE2   . GLN   A 1 1001 ? 193.757 124.031 96.365  1.00 52.10  ? 1001 GLN   C NE2   1 
ATOM   6251 N N     . ASN   A 1 1002 ? 190.700 129.398 95.678  1.00 36.01  ? 1002 ASN   C N     1 
ATOM   6252 C CA    . ASN   A 1 1002 ? 189.584 130.303 95.902  1.00 36.91  ? 1002 ASN   C CA    1 
ATOM   6253 C C     . ASN   A 1 1002 ? 189.926 131.461 96.836  1.00 36.45  ? 1002 ASN   C C     1 
ATOM   6254 O O     . ASN   A 1 1002 ? 190.466 131.258 97.924  1.00 36.65  ? 1002 ASN   C O     1 
ATOM   6255 C CB    . ASN   A 1 1002 ? 188.430 129.528 96.508  1.00 41.60  ? 1002 ASN   C CB    1 
ATOM   6256 C CG    . ASN   A 1 1002 ? 188.203 128.208 95.831  1.00 46.96  ? 1002 ASN   C CG    1 
ATOM   6257 O OD1   . ASN   A 1 1002 ? 188.904 127.863 94.871  1.00 50.21  ? 1002 ASN   C OD1   1 
ATOM   6258 N ND2   . ASN   A 1 1002 ? 187.240 127.464 96.309  1.00 52.51  ? 1002 ASN   C ND2   1 
ATOM   6259 N N     . LEU   A 1 1003 ? 189.567 132.672 96.414  1.00 32.96  ? 1003 LEU   C N     1 
ATOM   6260 C CA    . LEU   A 1 1003 ? 189.728 133.870 97.237  1.00 29.49  ? 1003 LEU   C CA    1 
ATOM   6261 C C     . LEU   A 1 1003 ? 188.395 134.278 97.844  1.00 30.68  ? 1003 LEU   C C     1 
ATOM   6262 O O     . LEU   A 1 1003 ? 188.275 135.350 98.438  1.00 34.09  ? 1003 LEU   C O     1 
ATOM   6263 C CB    . LEU   A 1 1003 ? 190.272 135.034 96.409  1.00 38.05  ? 1003 LEU   C CB    1 
ATOM   6264 C CG    . LEU   A 1 1003 ? 191.661 134.861 95.801  1.00 51.97  ? 1003 LEU   C CG    1 
ATOM   6265 C CD1   . LEU   A 1 1003 ? 191.940 136.051 94.917  1.00 63.73  ? 1003 LEU   C CD1   1 
ATOM   6266 C CD2   . LEU   A 1 1003 ? 192.716 134.761 96.907  1.00 44.85  ? 1003 LEU   C CD2   1 
ATOM   6267 N N     . GLY   A 1 1004 ? 187.395 133.424 97.673  1.00 27.72  ? 1004 GLY   C N     1 
ATOM   6268 C CA    . GLY   A 1 1004 ? 186.059 133.690 98.180  1.00 27.74  ? 1004 GLY   C CA    1 
ATOM   6269 C C     . GLY   A 1 1004 ? 185.420 134.905 97.517  1.00 33.13  ? 1004 GLY   C C     1 
ATOM   6270 O O     . GLY   A 1 1004 ? 185.302 134.970 96.298  1.00 40.07  ? 1004 GLY   C O     1 
ATOM   6271 N N     . LEU   A 1 1005 ? 184.992 135.854 98.342  1.00 32.92  ? 1005 LEU   C N     1 
ATOM   6272 C CA    . LEU   A 1 1005 ? 184.305 137.074 97.909  1.00 35.19  ? 1005 LEU   C CA    1 
ATOM   6273 C C     . LEU   A 1 1005 ? 182.910 136.748 97.391  1.00 37.81  ? 1005 LEU   C C     1 
ATOM   6274 O O     . LEU   A 1 1005 ? 182.302 137.532 96.662  1.00 46.48  ? 1005 LEU   C O     1 
ATOM   6275 C CB    . LEU   A 1 1005 ? 185.100 137.807 96.817  1.00 37.46  ? 1005 LEU   C CB    1 
ATOM   6276 C CG    . LEU   A 1 1005 ? 186.576 138.097 97.123  1.00 36.72  ? 1005 LEU   C CG    1 
ATOM   6277 C CD1   . LEU   A 1 1005 ? 187.192 138.821 95.942  1.00 50.88  ? 1005 LEU   C CD1   1 
ATOM   6278 C CD2   . LEU   A 1 1005 ? 186.681 138.926 98.384  1.00 38.36  ? 1005 LEU   C CD2   1 
ATOM   6279 N N     . SER   A 1 1006 ? 182.403 135.590 97.793  1.00 32.86  ? 1006 SER   C N     1 
ATOM   6280 C CA    . SER   A 1 1006 ? 181.062 135.157 97.438  1.00 32.92  ? 1006 SER   C CA    1 
ATOM   6281 C C     . SER   A 1 1006 ? 180.032 135.725 98.401  1.00 33.29  ? 1006 SER   C C     1 
ATOM   6282 O O     . SER   A 1 1006 ? 180.374 136.258 99.455  1.00 36.37  ? 1006 SER   C O     1 
ATOM   6283 C CB    . SER   A 1 1006 ? 180.986 133.644 97.442  1.00 36.41  ? 1006 SER   C CB    1 
ATOM   6284 O OG    . SER   A 1 1006 ? 181.086 133.144 98.746  1.00 39.13  ? 1006 SER   C OG    1 
ATOM   6285 N N     . GLU   A 1 1007 ? 178.762 135.607 98.034  1.00 36.41  ? 1007 GLU   C N     1 
ATOM   6286 C CA    . GLU   A 1 1007 ? 177.654 136.030 98.887  1.00 34.97  ? 1007 GLU   C CA    1 
ATOM   6287 C C     . GLU   A 1 1007 ? 177.770 137.488 99.316  1.00 35.43  ? 1007 GLU   C C     1 
ATOM   6288 O O     . GLU   A 1 1007 ? 177.351 137.863 100.410 1.00 38.74  ? 1007 GLU   C O     1 
ATOM   6289 C CB    . GLU   A 1 1007 ? 177.566 135.134 100.123 1.00 37.45  ? 1007 GLU   C CB    1 
ATOM   6290 C CG    . GLU   A 1 1007 ? 177.385 133.656 99.822  1.00 39.88  ? 1007 GLU   C CG    1 
ATOM   6291 C CD    . GLU   A 1 1007 ? 176.042 133.336 99.230  1.00 45.93  ? 1007 GLU   C CD    1 
ATOM   6292 O OE1   . GLU   A 1 1007 ? 175.157 134.149 99.338  1.00 44.38  ? 1007 GLU   C OE1   1 
ATOM   6293 O OE2   . GLU   A 1 1007 ? 175.901 132.277 98.667  1.00 50.72  ? 1007 GLU   C OE2   1 
ATOM   6294 N N     . MET   A 1 1008 ? 178.312 138.311 98.437  1.00 38.83  ? 1008 MET   C N     1 
ATOM   6295 C CA    . MET   A 1 1008 ? 178.417 139.741 98.665  1.00 44.24  ? 1008 MET   C CA    1 
ATOM   6296 C C     . MET   A 1 1008 ? 178.264 140.424 97.329  1.00 53.67  ? 1008 MET   C C     1 
ATOM   6297 O O     . MET   A 1 1008 ? 178.406 139.782 96.291  1.00 55.24  ? 1008 MET   C O     1 
ATOM   6298 C CB    . MET   A 1 1008 ? 179.731 140.108 99.347  1.00 39.77  ? 1008 MET   C CB    1 
ATOM   6299 C CG    . MET   A 1 1008 ? 180.971 139.808 98.554  1.00 42.88  ? 1008 MET   C CG    1 
ATOM   6300 S SD    . MET   A 1 1008 ? 182.493 140.321 99.406  1.00 39.78  ? 1008 MET   C SD    1 
ATOM   6301 C CE    . MET   A 1 1008 ? 182.603 139.175 100.753 1.00 33.00  ? 1008 MET   C CE    1 
ATOM   6302 N N     . TYR   A 1 1009 ? 177.943 141.704 97.326  1.00 51.64  ? 1009 TYR   C N     1 
ATOM   6303 C CA    . TYR   A 1 1009 ? 177.717 142.357 96.050  1.00 55.47  ? 1009 TYR   C CA    1 
ATOM   6304 C C     . TYR   A 1 1009 ? 178.616 143.554 95.849  1.00 60.14  ? 1009 TYR   C C     1 
ATOM   6305 O O     . TYR   A 1 1009 ? 179.000 144.234 96.801  1.00 63.37  ? 1009 TYR   C O     1 
ATOM   6306 C CB    . TYR   A 1 1009 ? 176.248 142.723 95.924  1.00 55.38  ? 1009 TYR   C CB    1 
ATOM   6307 C CG    . TYR   A 1 1009 ? 175.385 141.494 96.013  1.00 52.40  ? 1009 TYR   C CG    1 
ATOM   6308 C CD1   . TYR   A 1 1009 ? 174.886 141.097 97.239  1.00 51.11  ? 1009 TYR   C CD1   1 
ATOM   6309 C CD2   . TYR   A 1 1009 ? 175.117 140.747 94.880  1.00 56.24  ? 1009 TYR   C CD2   1 
ATOM   6310 C CE1   . TYR   A 1 1009 ? 174.121 139.958 97.336  1.00 52.54  ? 1009 TYR   C CE1   1 
ATOM   6311 C CE2   . TYR   A 1 1009 ? 174.349 139.605 94.975  1.00 57.28  ? 1009 TYR   C CE2   1 
ATOM   6312 C CZ    . TYR   A 1 1009 ? 173.851 139.212 96.199  1.00 54.80  ? 1009 TYR   C CZ    1 
ATOM   6313 O OH    . TYR   A 1 1009 ? 173.085 138.073 96.297  1.00 52.65  ? 1009 TYR   C OH    1 
ATOM   6314 N N     . PHE   A 1 1010 ? 178.957 143.792 94.594  1.00 67.88  ? 1010 PHE   C N     1 
ATOM   6315 C CA    . PHE   A 1 1010 ? 179.859 144.862 94.219  1.00 71.99  ? 1010 PHE   C CA    1 
ATOM   6316 C C     . PHE   A 1 1010 ? 179.276 145.712 93.108  1.00 86.26  ? 1010 PHE   C C     1 
ATOM   6317 O O     . PHE   A 1 1010 ? 178.340 145.301 92.420  1.00 83.49  ? 1010 PHE   C O     1 
ATOM   6318 C CB    . PHE   A 1 1010 ? 181.186 144.302 93.742  1.00 86.56  ? 1010 PHE   C CB    1 
ATOM   6319 C CG    . PHE   A 1 1010 ? 181.867 143.403 94.685  1.00 69.89  ? 1010 PHE   C CG    1 
ATOM   6320 C CD1   . PHE   A 1 1010 ? 181.906 142.046 94.439  1.00 66.89  ? 1010 PHE   C CD1   1 
ATOM   6321 C CD2   . PHE   A 1 1010 ? 182.473 143.894 95.818  1.00 67.18  ? 1010 PHE   C CD2   1 
ATOM   6322 C CE1   . PHE   A 1 1010 ? 182.548 141.199 95.303  1.00 61.81  ? 1010 PHE   C CE1   1 
ATOM   6323 C CE2   . PHE   A 1 1010 ? 183.111 143.050 96.683  1.00 63.11  ? 1010 PHE   C CE2   1 
ATOM   6324 C CZ    . PHE   A 1 1010 ? 183.149 141.699 96.418  1.00 57.45  ? 1010 PHE   C CZ    1 
ATOM   6325 N N     . ASN   A 1 1011 ? 179.855 146.889 92.917  1.00 90.94  ? 1011 ASN   C N     1 
ATOM   6326 C CA    . ASN   A 1 1011 ? 179.455 147.756 91.822  1.00 95.06  ? 1011 ASN   C CA    1 
ATOM   6327 C C     . ASN   A 1 1011 ? 180.081 147.293 90.508  1.00 99.66  ? 1011 ASN   C C     1 
ATOM   6328 O O     . ASN   A 1 1011 ? 180.804 146.295 90.471  1.00 100.17 ? 1011 ASN   C O     1 
ATOM   6329 C CB    . ASN   A 1 1011 ? 179.818 149.194 92.143  1.00 100.63 ? 1011 ASN   C CB    1 
ATOM   6330 C CG    . ASN   A 1 1011 ? 181.310 149.419 92.301  1.00 100.95 ? 1011 ASN   C CG    1 
ATOM   6331 O OD1   . ASN   A 1 1011 ? 182.152 148.636 91.831  1.00 99.18  ? 1011 ASN   C OD1   1 
ATOM   6332 N ND2   . ASN   A 1 1011 ? 181.649 150.488 92.973  1.00 98.24  ? 1011 ASN   C ND2   1 
ATOM   6333 N N     . TYR   A 1 1012 ? 179.774 148.002 89.427  1.00 102.76 ? 1012 TYR   C N     1 
ATOM   6334 C CA    . TYR   A 1 1012 ? 180.225 147.607 88.096  1.00 107.70 ? 1012 TYR   C CA    1 
ATOM   6335 C C     . TYR   A 1 1012 ? 181.740 147.566 87.964  1.00 119.59 ? 1012 TYR   C C     1 
ATOM   6336 O O     . TYR   A 1 1012 ? 182.302 146.583 87.470  1.00 111.17 ? 1012 TYR   C O     1 
ATOM   6337 C CB    . TYR   A 1 1012 ? 179.644 148.551 87.047  1.00 107.12 ? 1012 TYR   C CB    1 
ATOM   6338 C CG    . TYR   A 1 1012 ? 180.151 148.284 85.657  1.00 112.20 ? 1012 TYR   C CG    1 
ATOM   6339 C CD1   . TYR   A 1 1012 ? 179.615 147.247 84.910  1.00 130.51 ? 1012 TYR   C CD1   1 
ATOM   6340 C CD2   . TYR   A 1 1012 ? 181.157 149.075 85.128  1.00 110.11 ? 1012 TYR   C CD2   1 
ATOM   6341 C CE1   . TYR   A 1 1012 ? 180.083 147.006 83.635  1.00 115.29 ? 1012 TYR   C CE1   1 
ATOM   6342 C CE2   . TYR   A 1 1012 ? 181.625 148.834 83.856  1.00 127.77 ? 1012 TYR   C CE2   1 
ATOM   6343 C CZ    . TYR   A 1 1012 ? 181.092 147.805 83.109  1.00 115.93 ? 1012 TYR   C CZ    1 
ATOM   6344 O OH    . TYR   A 1 1012 ? 181.558 147.568 81.837  1.00 123.35 ? 1012 TYR   C OH    1 
ATOM   6345 N N     . GLU   A 1 1013 ? 182.401 148.633 88.379  1.00 145.59 ? 1013 GLU   C N     1 
ATOM   6346 C CA    . GLU   A 1 1013 ? 183.839 148.756 88.215  1.00 102.40 ? 1013 GLU   C CA    1 
ATOM   6347 C C     . GLU   A 1 1013 ? 184.601 147.679 88.981  1.00 109.98 ? 1013 GLU   C C     1 
ATOM   6348 O O     . GLU   A 1 1013 ? 185.591 147.140 88.488  1.00 98.63  ? 1013 GLU   C O     1 
ATOM   6349 C CB    . GLU   A 1 1013 ? 184.290 150.145 88.659  1.00 108.44 ? 1013 GLU   C CB    1 
ATOM   6350 C CG    . GLU   A 1 1013 ? 183.769 151.277 87.772  1.00 118.90 ? 1013 GLU   C CG    1 
ATOM   6351 C CD    . GLU   A 1 1013 ? 182.324 151.623 88.046  1.00 108.11 ? 1013 GLU   C CD    1 
ATOM   6352 O OE1   . GLU   A 1 1013 ? 181.764 151.072 88.966  1.00 110.86 ? 1013 GLU   C OE1   1 
ATOM   6353 O OE2   . GLU   A 1 1013 ? 181.781 152.428 87.330  1.00 120.45 ? 1013 GLU   C OE2   1 
ATOM   6354 N N     . THR   A 1 1014 ? 184.127 147.360 90.183  1.00 102.88 ? 1014 THR   C N     1 
ATOM   6355 C CA    . THR   A 1 1014 ? 184.774 146.341 90.998  1.00 99.86  ? 1014 THR   C CA    1 
ATOM   6356 C C     . THR   A 1 1014 ? 184.632 144.971 90.354  1.00 142.55 ? 1014 THR   C C     1 
ATOM   6357 O O     . THR   A 1 1014 ? 185.598 144.202 90.299  1.00 89.55  ? 1014 THR   C O     1 
ATOM   6358 C CB    . THR   A 1 1014 ? 184.179 146.320 92.411  1.00 99.89  ? 1014 THR   C CB    1 
ATOM   6359 O OG1   . THR   A 1 1014 ? 184.371 147.601 93.023  1.00 91.00  ? 1014 THR   C OG1   1 
ATOM   6360 C CG2   . THR   A 1 1014 ? 184.851 145.238 93.266  1.00 95.42  ? 1014 THR   C CG2   1 
ATOM   6361 N N     . LYS   A 1 1015 ? 183.436 144.653 89.860  1.00 95.42  ? 1015 LYS   C N     1 
ATOM   6362 C CA    . LYS   A 1 1015 ? 183.218 143.375 89.203  1.00 96.96  ? 1015 LYS   C CA    1 
ATOM   6363 C C     . LYS   A 1 1015 ? 184.089 143.253 87.956  1.00 101.65 ? 1015 LYS   C C     1 
ATOM   6364 O O     . LYS   A 1 1015 ? 184.641 142.195 87.680  1.00 121.41 ? 1015 LYS   C O     1 
ATOM   6365 C CB    . LYS   A 1 1015 ? 181.746 143.181 88.853  1.00 106.60 ? 1015 LYS   C CB    1 
ATOM   6366 C CG    . LYS   A 1 1015 ? 180.858 142.937 90.064  1.00 93.23  ? 1015 LYS   C CG    1 
ATOM   6367 C CD    . LYS   A 1 1015 ? 179.455 142.508 89.674  1.00 100.85 ? 1015 LYS   C CD    1 
ATOM   6368 C CE    . LYS   A 1 1015 ? 178.633 143.680 89.160  1.00 101.77 ? 1015 LYS   C CE    1 
ATOM   6369 N NZ    . LYS   A 1 1015 ? 177.197 143.320 89.010  1.00 105.98 ? 1015 LYS   C NZ    1 
ATOM   6370 N N     . SER   A 1 1016 ? 184.226 144.364 87.228  1.00 100.69 ? 1016 SER   C N     1 
ATOM   6371 C CA    . SER   A 1 1016 ? 185.075 144.373 86.037  1.00 103.68 ? 1016 SER   C CA    1 
ATOM   6372 C C     . SER   A 1 1016 ? 186.514 144.099 86.423  1.00 106.50 ? 1016 SER   C C     1 
ATOM   6373 O O     . SER   A 1 1016 ? 187.207 143.310 85.742  1.00 90.37  ? 1016 SER   C O     1 
ATOM   6374 C CB    . SER   A 1 1016 ? 184.971 145.723 85.347  1.00 105.42 ? 1016 SER   C CB    1 
ATOM   6375 O OG    . SER   A 1 1016 ? 185.777 145.757 84.200  1.00 113.95 ? 1016 SER   C OG    1 
ATOM   6376 N N     . ALA   A 1 1017 ? 186.997 144.707 87.493  1.00 97.93  ? 1017 ALA   C N     1 
ATOM   6377 C CA    . ALA   A 1 1017 ? 188.334 144.499 87.990  1.00 105.41 ? 1017 ALA   C CA    1 
ATOM   6378 C C     . ALA   A 1 1017 ? 188.584 143.028 88.344  1.00 90.78  ? 1017 ALA   C C     1 
ATOM   6379 O O     . ALA   A 1 1017 ? 189.615 142.470 88.047  1.00 98.07  ? 1017 ALA   C O     1 
ATOM   6380 C CB    . ALA   A 1 1017 ? 188.636 145.381 89.175  1.00 104.94 ? 1017 ALA   C CB    1 
ATOM   6381 N N     . LEU   A 1 1018 ? 187.565 142.417 88.987  1.00 95.24  ? 1018 LEU   C N     1 
ATOM   6382 C CA    . LEU   A 1 1018 ? 187.696 141.003 89.359  1.00 101.80 ? 1018 LEU   C CA    1 
ATOM   6383 C C     . LEU   A 1 1018 ? 187.731 140.099 88.137  1.00 91.31  ? 1018 LEU   C C     1 
ATOM   6384 O O     . LEU   A 1 1018 ? 188.545 139.164 88.083  1.00 88.07  ? 1018 LEU   C O     1 
ATOM   6385 C CB    . LEU   A 1 1018 ? 186.516 140.592 90.261  1.00 92.82  ? 1018 LEU   C CB    1 
ATOM   6386 C CG    . LEU   A 1 1018 ? 186.532 141.138 91.709  1.00 93.32  ? 1018 LEU   C CG    1 
ATOM   6387 C CD1   . LEU   A 1 1018 ? 185.192 140.825 92.382  1.00 84.53  ? 1018 LEU   C CD1   1 
ATOM   6388 C CD2   . LEU   A 1 1018 ? 187.673 140.489 92.483  1.00 93.68  ? 1018 LEU   C CD2   1 
ATOM   6389 N N     . GLU   A 1 1019 ? 186.905 140.378 87.137  1.00 89.33  ? 1019 GLU   C N     1 
ATOM   6390 C CA    . GLU   A 1 1019 ? 186.922 139.593 85.915  1.00 98.91  ? 1019 GLU   C CA    1 
ATOM   6391 C C     . GLU   A 1 1019 ? 188.267 139.753 85.218  1.00 98.08  ? 1019 GLU   C C     1 
ATOM   6392 O O     . GLU   A 1 1019 ? 188.833 138.793 84.695  1.00 106.78 ? 1019 GLU   C O     1 
ATOM   6393 C CB    . GLU   A 1 1019 ? 185.797 140.010 84.969  1.00 112.29 ? 1019 GLU   C CB    1 
ATOM   6394 C CG    . GLU   A 1 1019 ? 184.396 139.634 85.435  1.00 114.10 ? 1019 GLU   C CG    1 
ATOM   6395 C CD    . GLU   A 1 1019 ? 183.323 140.130 84.503  1.00 108.04 ? 1019 GLU   C CD    1 
ATOM   6396 O OE1   . GLU   A 1 1019 ? 183.643 140.874 83.607  1.00 122.40 ? 1019 GLU   C OE1   1 
ATOM   6397 O OE2   . GLU   A 1 1019 ? 182.187 139.765 84.684  1.00 111.88 ? 1019 GLU   C OE2   1 
ATOM   6398 N N     . THR   A 1 1020 ? 188.785 140.978 85.243  1.00 164.62 ? 1020 THR   C N     1 
ATOM   6399 C CA    . THR   A 1 1020 ? 190.073 141.274 84.641  1.00 96.78  ? 1020 THR   C CA    1 
ATOM   6400 C C     . THR   A 1 1020 ? 191.170 140.490 85.348  1.00 125.24 ? 1020 THR   C C     1 
ATOM   6401 O O     . THR   A 1 1020 ? 191.997 139.849 84.699  1.00 115.86 ? 1020 THR   C O     1 
ATOM   6402 C CB    . THR   A 1 1020 ? 190.369 142.785 84.709  1.00 106.91 ? 1020 THR   C CB    1 
ATOM   6403 O OG1   . THR   A 1 1020 ? 189.351 143.502 83.997  1.00 104.34 ? 1020 THR   C OG1   1 
ATOM   6404 C CG2   . THR   A 1 1020 ? 191.714 143.084 84.087  1.00 105.69 ? 1020 THR   C CG2   1 
ATOM   6405 N N     . LEU   A 1 1021 ? 191.142 140.490 86.679  1.00 99.24  ? 1021 LEU   C N     1 
ATOM   6406 C CA    . LEU   A 1 1021 ? 192.120 139.760 87.480  1.00 97.50  ? 1021 LEU   C CA    1 
ATOM   6407 C C     . LEU   A 1 1021 ? 192.175 138.297 87.063  1.00 89.63  ? 1021 LEU   C C     1 
ATOM   6408 O O     . LEU   A 1 1021 ? 193.256 137.721 86.918  1.00 96.25  ? 1021 LEU   C O     1 
ATOM   6409 C CB    . LEU   A 1 1021 ? 191.743 139.854 88.968  1.00 111.01 ? 1021 LEU   C CB    1 
ATOM   6410 C CG    . LEU   A 1 1021 ? 192.658 139.133 89.983  1.00 99.64  ? 1021 LEU   C CG    1 
ATOM   6411 C CD1   . LEU   A 1 1021 ? 194.049 139.785 90.003  1.00 97.37  ? 1021 LEU   C CD1   1 
ATOM   6412 C CD2   . LEU   A 1 1021 ? 191.997 139.196 91.359  1.00 94.16  ? 1021 LEU   C CD2   1 
ATOM   6413 N N     . GLN   A 1 1022 ? 191.003 137.699 86.855  1.00 99.54  ? 1022 GLN   C N     1 
ATOM   6414 C CA    . GLN   A 1 1022 ? 190.920 136.299 86.462  1.00 99.13  ? 1022 GLN   C CA    1 
ATOM   6415 C C     . GLN   A 1 1022 ? 191.632 136.025 85.139  1.00 107.62 ? 1022 GLN   C C     1 
ATOM   6416 O O     . GLN   A 1 1022 ? 192.269 134.984 84.977  1.00 102.67 ? 1022 GLN   C O     1 
ATOM   6417 C CB    . GLN   A 1 1022 ? 189.456 135.865 86.330  1.00 99.73  ? 1022 GLN   C CB    1 
ATOM   6418 C CG    . GLN   A 1 1022 ? 189.271 134.389 85.992  1.00 97.73  ? 1022 GLN   C CG    1 
ATOM   6419 C CD    . GLN   A 1 1022 ? 189.739 133.486 87.103  1.00 90.29  ? 1022 GLN   C CD    1 
ATOM   6420 O OE1   . GLN   A 1 1022 ? 189.055 133.350 88.122  1.00 80.92  ? 1022 GLN   C OE1   1 
ATOM   6421 N NE2   . GLN   A 1 1022 ? 190.909 132.875 86.918  1.00 87.37  ? 1022 GLN   C NE2   1 
ATOM   6422 N N     . GLU   A 1 1023 ? 191.507 136.951 84.190  1.00 101.20 ? 1023 GLU   C N     1 
ATOM   6423 C CA    . GLU   A 1 1023 ? 192.123 136.770 82.878  1.00 108.60 ? 1023 GLU   C CA    1 
ATOM   6424 C C     . GLU   A 1 1023 ? 193.602 137.148 82.865  1.00 109.89 ? 1023 GLU   C C     1 
ATOM   6425 O O     . GLU   A 1 1023 ? 194.406 136.505 82.183  1.00 97.30  ? 1023 GLU   C O     1 
ATOM   6426 C CB    . GLU   A 1 1023 ? 191.380 137.592 81.823  1.00 120.31 ? 1023 GLU   C CB    1 
ATOM   6427 C CG    . GLU   A 1 1023 ? 189.967 137.108 81.522  1.00 112.39 ? 1023 GLU   C CG    1 
ATOM   6428 C CD    . GLU   A 1 1023 ? 189.309 137.879 80.402  1.00 120.36 ? 1023 GLU   C CD    1 
ATOM   6429 O OE1   . GLU   A 1 1023 ? 189.890 138.835 79.942  1.00 127.53 ? 1023 GLU   C OE1   1 
ATOM   6430 O OE2   . GLU   A 1 1023 ? 188.230 137.508 80.003  1.00 127.28 ? 1023 GLU   C OE2   1 
ATOM   6431 N N     . GLU   A 1 1024 ? 193.962 138.192 83.604  1.00 104.95 ? 1024 GLU   C N     1 
ATOM   6432 C CA    . GLU   A 1 1024 ? 195.340 138.669 83.627  1.00 106.42 ? 1024 GLU   C CA    1 
ATOM   6433 C C     . GLU   A 1 1024 ? 196.284 137.706 84.332  1.00 107.62 ? 1024 GLU   C C     1 
ATOM   6434 O O     . GLU   A 1 1024 ? 197.446 137.578 83.940  1.00 101.22 ? 1024 GLU   C O     1 
ATOM   6435 C CB    . GLU   A 1 1024 ? 195.435 140.050 84.274  1.00 110.49 ? 1024 GLU   C CB    1 
ATOM   6436 C CG    . GLU   A 1 1024 ? 194.892 141.186 83.416  1.00 118.47 ? 1024 GLU   C CG    1 
ATOM   6437 C CD    . GLU   A 1 1024 ? 195.095 142.538 84.042  1.00 117.07 ? 1024 GLU   C CD    1 
ATOM   6438 O OE1   . GLU   A 1 1024 ? 195.402 142.588 85.212  1.00 103.10 ? 1024 GLU   C OE1   1 
ATOM   6439 O OE2   . GLU   A 1 1024 ? 194.944 143.521 83.358  1.00 114.09 ? 1024 GLU   C OE2   1 
ATOM   6440 N N     . LYS   A 1 1025 ? 195.794 137.029 85.371  1.00 106.71 ? 1025 LYS   C N     1 
ATOM   6441 C CA    . LYS   A 1 1025 ? 196.624 136.102 86.137  1.00 103.93 ? 1025 LYS   C CA    1 
ATOM   6442 C C     . LYS   A 1 1025 ? 196.004 134.701 86.261  1.00 98.83  ? 1025 LYS   C C     1 
ATOM   6443 O O     . LYS   A 1 1025 ? 195.451 134.372 87.313  1.00 96.19  ? 1025 LYS   C O     1 
ATOM   6444 C CB    . LYS   A 1 1025 ? 196.884 136.668 87.541  1.00 104.00 ? 1025 LYS   C CB    1 
ATOM   6445 C CG    . LYS   A 1 1025 ? 197.585 138.034 87.573  1.00 106.46 ? 1025 LYS   C CG    1 
ATOM   6446 C CD    . LYS   A 1 1025 ? 199.022 137.944 87.067  1.00 105.11 ? 1025 LYS   C CD    1 
ATOM   6447 C CE    . LYS   A 1 1025 ? 199.744 139.272 87.180  1.00 103.65 ? 1025 LYS   C CE    1 
ATOM   6448 N NZ    . LYS   A 1 1025 ? 201.119 139.199 86.614  1.00 102.88 ? 1025 LYS   C NZ    1 
ATOM   6449 N N     . PRO   A 1 1026 ? 196.130 133.851 85.222  1.00 97.26  ? 1026 PRO   C N     1 
ATOM   6450 C CA    . PRO   A 1 1026 ? 195.560 132.514 85.085  1.00 98.97  ? 1026 PRO   C CA    1 
ATOM   6451 C C     . PRO   A 1 1026 ? 195.983 131.578 86.210  1.00 96.70  ? 1026 PRO   C C     1 
ATOM   6452 O O     . PRO   A 1 1026 ? 195.340 130.556 86.448  1.00 91.75  ? 1026 PRO   C O     1 
ATOM   6453 C CB    . PRO   A 1 1026 ? 196.144 132.032 83.749  1.00 100.35 ? 1026 PRO   C CB    1 
ATOM   6454 C CG    . PRO   A 1 1026 ? 196.471 133.288 82.995  1.00 108.19 ? 1026 PRO   C CG    1 
ATOM   6455 C CD    . PRO   A 1 1026 ? 196.910 134.272 84.049  1.00 99.94  ? 1026 PRO   C CD    1 
ATOM   6456 N N     . GLU   A 1 1027 ? 197.066 131.926 86.899  1.00 94.61  ? 1027 GLU   C N     1 
ATOM   6457 C CA    . GLU   A 1 1027 ? 197.575 131.124 88.002  1.00 90.33  ? 1027 GLU   C CA    1 
ATOM   6458 C C     . GLU   A 1 1027 ? 196.531 130.949 89.097  1.00 82.77  ? 1027 GLU   C C     1 
ATOM   6459 O O     . GLU   A 1 1027 ? 196.556 129.961 89.832  1.00 80.29  ? 1027 GLU   C O     1 
ATOM   6460 C CB    . GLU   A 1 1027 ? 198.835 131.762 88.593  1.00 93.97  ? 1027 GLU   C CB    1 
ATOM   6461 C CG    . GLU   A 1 1027 ? 200.069 131.712 87.692  1.00 100.36 ? 1027 GLU   C CG    1 
ATOM   6462 C CD    . GLU   A 1 1027 ? 200.124 132.828 86.681  1.00 99.61  ? 1027 GLU   C CD    1 
ATOM   6463 O OE1   . GLU   A 1 1027 ? 199.119 133.455 86.455  1.00 105.38 ? 1027 GLU   C OE1   1 
ATOM   6464 O OE2   . GLU   A 1 1027 ? 201.177 133.052 86.134  1.00 102.92 ? 1027 GLU   C OE2   1 
ATOM   6465 N N     . LEU   A 1 1028 ? 195.609 131.903 89.203  1.00 78.97  ? 1028 LEU   C N     1 
ATOM   6466 C CA    . LEU   A 1 1028 ? 194.558 131.814 90.203  1.00 77.95  ? 1028 LEU   C CA    1 
ATOM   6467 C C     . LEU   A 1 1028 ? 193.411 130.967 89.686  1.00 74.48  ? 1028 LEU   C C     1 
ATOM   6468 O O     . LEU   A 1 1028 ? 192.768 131.314 88.694  1.00 79.13  ? 1028 LEU   C O     1 
ATOM   6469 C CB    . LEU   A 1 1028 ? 194.040 133.209 90.566  1.00 69.38  ? 1028 LEU   C CB    1 
ATOM   6470 C CG    . LEU   A 1 1028 ? 192.832 133.239 91.511  1.00 66.13  ? 1028 LEU   C CG    1 
ATOM   6471 C CD1   . LEU   A 1 1028 ? 193.197 132.600 92.847  1.00 63.19  ? 1028 LEU   C CD1   1 
ATOM   6472 C CD2   . LEU   A 1 1028 ? 192.396 134.669 91.704  1.00 69.91  ? 1028 LEU   C CD2   1 
ATOM   6473 N N     . THR   A 1 1029 ? 193.161 129.850 90.361  1.00 72.73  ? 1029 THR   C N     1 
ATOM   6474 C CA    . THR   A 1 1029 ? 192.165 128.889 89.916  1.00 76.23  ? 1029 THR   C CA    1 
ATOM   6475 C C     . THR   A 1 1029 ? 190.877 129.591 89.501  1.00 73.17  ? 1029 THR   C C     1 
ATOM   6476 O O     . THR   A 1 1029 ? 190.586 129.708 88.310  1.00 76.12  ? 1029 THR   C O     1 
ATOM   6477 C CB    . THR   A 1 1029 ? 191.886 127.849 91.030  1.00 70.15  ? 1029 THR   C CB    1 
ATOM   6478 O OG1   . THR   A 1 1029 ? 193.101 127.161 91.350  1.00 66.23  ? 1029 THR   C OG1   1 
ATOM   6479 C CG2   . THR   A 1 1029 ? 190.855 126.826 90.580  1.00 74.16  ? 1029 THR   C CG2   1 
ATOM   6480 N N     . VAL   A 1 1030 ? 190.115 130.066 90.481  1.00 74.26  ? 1030 VAL   C N     1 
ATOM   6481 C CA    . VAL   A 1 1030 ? 188.911 130.840 90.214  1.00 72.19  ? 1030 VAL   C CA    1 
ATOM   6482 C C     . VAL   A 1 1030 ? 188.739 131.977 91.235  1.00 67.11  ? 1030 VAL   C C     1 
ATOM   6483 O O     . VAL   A 1 1030 ? 188.948 131.780 92.431  1.00 62.46  ? 1030 VAL   C O     1 
ATOM   6484 C CB    . VAL   A 1 1030 ? 187.669 129.904 90.178  1.00 75.60  ? 1030 VAL   C CB    1 
ATOM   6485 C CG1   . VAL   A 1 1030 ? 186.399 130.705 90.043  1.00 74.36  ? 1030 VAL   C CG1   1 
ATOM   6486 C CG2   . VAL   A 1 1030 ? 187.758 128.955 88.992  1.00 75.15  ? 1030 VAL   C CG2   1 
ATOM   6487 N N     . VAL   A 1 1031 ? 188.352 133.161 90.753  1.00 73.12  ? 1031 VAL   C N     1 
ATOM   6488 C CA    . VAL   A 1 1031 ? 188.049 134.314 91.608  1.00 69.39  ? 1031 VAL   C CA    1 
ATOM   6489 C C     . VAL   A 1 1031 ? 186.731 134.147 92.361  1.00 65.30  ? 1031 VAL   C C     1 
ATOM   6490 O O     . VAL   A 1 1031 ? 186.642 134.498 93.532  1.00 58.05  ? 1031 VAL   C O     1 
ATOM   6491 C CB    . VAL   A 1 1031 ? 187.994 135.618 90.788  1.00 77.71  ? 1031 VAL   C CB    1 
ATOM   6492 C CG1   . VAL   A 1 1031 ? 187.469 136.758 91.656  1.00 81.87  ? 1031 VAL   C CG1   1 
ATOM   6493 C CG2   . VAL   A 1 1031 ? 189.385 135.973 90.277  1.00 90.46  ? 1031 VAL   C CG2   1 
ATOM   6494 N N     . PHE   A 1 1032 ? 185.715 133.627 91.671  1.00 68.46  ? 1032 PHE   C N     1 
ATOM   6495 C CA    . PHE   A 1 1032 ? 184.370 133.397 92.218  1.00 67.79  ? 1032 PHE   C CA    1 
ATOM   6496 C C     . PHE   A 1 1032 ? 183.570 134.666 92.468  1.00 69.07  ? 1032 PHE   C C     1 
ATOM   6497 O O     . PHE   A 1 1032 ? 183.045 134.874 93.562  1.00 63.80  ? 1032 PHE   C O     1 
ATOM   6498 C CB    . PHE   A 1 1032 ? 184.417 132.595 93.525  1.00 63.27  ? 1032 PHE   C CB    1 
ATOM   6499 C CG    . PHE   A 1 1032 ? 184.903 131.211 93.370  1.00 66.32  ? 1032 PHE   C CG    1 
ATOM   6500 C CD1   . PHE   A 1 1032 ? 186.223 130.892 93.545  1.00 63.70  ? 1032 PHE   C CD1   1 
ATOM   6501 C CD2   . PHE   A 1 1032 ? 184.016 130.207 93.055  1.00 73.83  ? 1032 PHE   C CD2   1 
ATOM   6502 C CE1   . PHE   A 1 1032 ? 186.644 129.601 93.400  1.00 64.32  ? 1032 PHE   C CE1   1 
ATOM   6503 C CE2   . PHE   A 1 1032 ? 184.438 128.911 92.916  1.00 70.18  ? 1032 PHE   C CE2   1 
ATOM   6504 C CZ    . PHE   A 1 1032 ? 185.758 128.611 93.087  1.00 68.04  ? 1032 PHE   C CZ    1 
ATOM   6505 N N     . GLU   A 1 1033 ? 183.418 135.480 91.434  1.00 74.59  ? 1033 GLU   C N     1 
ATOM   6506 C CA    . GLU   A 1 1033 ? 182.581 136.667 91.519  1.00 73.51  ? 1033 GLU   C CA    1 
ATOM   6507 C C     . GLU   A 1 1033 ? 181.150 136.241 91.851  1.00 74.65  ? 1033 GLU   C C     1 
ATOM   6508 O O     . GLU   A 1 1033 ? 180.718 135.169 91.425  1.00 77.74  ? 1033 GLU   C O     1 
ATOM   6509 C CB    . GLU   A 1 1033 ? 182.619 137.433 90.186  1.00 76.94  ? 1033 GLU   C CB    1 
ATOM   6510 C CG    . GLU   A 1 1033 ? 184.002 137.927 89.789  1.00 77.92  ? 1033 GLU   C CG    1 
ATOM   6511 C CD    . GLU   A 1 1033 ? 184.807 136.874 89.084  1.00 84.48  ? 1033 GLU   C CD    1 
ATOM   6512 O OE1   . GLU   A 1 1033 ? 184.346 135.758 88.997  1.00 75.94  ? 1033 GLU   C OE1   1 
ATOM   6513 O OE2   . GLU   A 1 1033 ? 185.882 137.176 88.638  1.00 88.65  ? 1033 GLU   C OE2   1 
ATOM   6514 N N     . PRO   A 1 1034 ? 180.400 137.058 92.601  1.00 76.08  ? 1034 PRO   C N     1 
ATOM   6515 C CA    . PRO   A 1 1034 ? 179.038 136.811 93.055  1.00 74.01  ? 1034 PRO   C CA    1 
ATOM   6516 C C     . PRO   A 1 1034 ? 178.013 136.717 91.927  1.00 79.59  ? 1034 PRO   C C     1 
ATOM   6517 O O     . PRO   A 1 1034 ? 176.926 136.171 92.122  1.00 78.66  ? 1034 PRO   C O     1 
ATOM   6518 C CB    . PRO   A 1 1034 ? 178.768 138.025 93.948  1.00 66.19  ? 1034 PRO   C CB    1 
ATOM   6519 C CG    . PRO   A 1 1034 ? 179.722 139.097 93.461  1.00 68.22  ? 1034 PRO   C CG    1 
ATOM   6520 C CD    . PRO   A 1 1034 ? 180.961 138.349 93.041  1.00 72.30  ? 1034 PRO   C CD    1 
ATOM   6521 N N     . SER   A 1 1035 ? 178.347 137.259 90.763  1.00 82.10  ? 1035 SER   C N     1 
ATOM   6522 C CA    . SER   A 1 1035 ? 177.439 137.239 89.621  1.00 82.62  ? 1035 SER   C CA    1 
ATOM   6523 C C     . SER   A 1 1035 ? 178.141 137.696 88.350  1.00 85.14  ? 1035 SER   C C     1 
ATOM   6524 O O     . SER   A 1 1035 ? 179.350 137.911 88.356  1.00 88.16  ? 1035 SER   C O     1 
ATOM   6525 C CB    . SER   A 1 1035 ? 176.240 138.132 89.875  1.00 84.48  ? 1035 SER   C CB    1 
ATOM   6526 O OG    . SER   A 1 1035 ? 175.399 138.152 88.757  1.00 85.53  ? 1035 SER   C OG    1 
HETATM 6527 P PG    . ATP   B 2 .    ? 143.553 92.471  94.235  1.00 35.14  ? 1201 ATP   C PG    1 
HETATM 6528 O O1G   . ATP   B 2 .    ? 143.945 91.687  93.051  1.00 31.97  ? 1201 ATP   C O1G   1 
HETATM 6529 O O2G   . ATP   B 2 .    ? 144.730 93.502  94.597  1.00 27.38  ? 1201 ATP   C O2G   1 
HETATM 6530 O O3G   . ATP   B 2 .    ? 142.262 93.326  93.847  1.00 23.34  ? 1201 ATP   C O3G   1 
HETATM 6531 P PB    . ATP   B 2 .    ? 144.424 91.200  96.466  1.00 17.46  ? 1201 ATP   C PB    1 
HETATM 6532 O O1B   . ATP   B 2 .    ? 145.725 91.414  95.800  1.00 19.84  ? 1201 ATP   C O1B   1 
HETATM 6533 O O2B   . ATP   B 2 .    ? 144.359 92.242  97.669  1.00 15.39  ? 1201 ATP   C O2B   1 
HETATM 6534 O O3B   . ATP   B 2 .    ? 143.187 91.468  95.455  1.00 23.97  ? 1201 ATP   C O3B   1 
HETATM 6535 P PA    . ATP   B 2 .    ? 143.094 89.346  97.861  1.00 14.57  ? 1201 ATP   C PA    1 
HETATM 6536 O O1A   . ATP   B 2 .    ? 142.001 88.983  96.938  1.00 19.74  ? 1201 ATP   C O1A   1 
HETATM 6537 O O2A   . ATP   B 2 .    ? 142.601 90.599  98.716  1.00 15.26  ? 1201 ATP   C O2A   1 
HETATM 6538 O O3A   . ATP   B 2 .    ? 144.424 89.681  97.021  1.00 17.92  ? 1201 ATP   C O3A   1 
HETATM 6539 O "O5'" . ATP   B 2 .    ? 143.384 88.133  98.898  1.00 13.18  ? 1201 ATP   C "O5'" 1 
HETATM 6540 C "C5'" . ATP   B 2 .    ? 142.995 86.823  98.412  1.00 14.23  ? 1201 ATP   C "C5'" 1 
HETATM 6541 C "C4'" . ATP   B 2 .    ? 143.027 85.838  99.603  1.00 14.02  ? 1201 ATP   C "C4'" 1 
HETATM 6542 O "O4'" . ATP   B 2 .    ? 143.756 86.438  100.704 1.00 12.79  ? 1201 ATP   C "O4'" 1 
HETATM 6543 C "C3'" . ATP   B 2 .    ? 141.613 85.542  100.150 1.00 18.89  ? 1201 ATP   C "C3'" 1 
HETATM 6544 O "O3'" . ATP   B 2 .    ? 141.074 84.362  99.538  1.00 27.70  ? 1201 ATP   C "O3'" 1 
HETATM 6545 C "C2'" . ATP   B 2 .    ? 141.860 85.268  101.643 1.00 18.47  ? 1201 ATP   C "C2'" 1 
HETATM 6546 O "O2'" . ATP   B 2 .    ? 142.076 83.866  101.834 1.00 21.34  ? 1201 ATP   C "O2'" 1 
HETATM 6547 C "C1'" . ATP   B 2 .    ? 143.123 86.101  101.974 1.00 12.81  ? 1201 ATP   C "C1'" 1 
HETATM 6548 N N9    . ATP   B 2 .    ? 142.769 87.337  102.710 1.00 13.21  ? 1201 ATP   C N9    1 
HETATM 6549 C C8    . ATP   B 2 .    ? 143.297 88.575  102.447 1.00 14.10  ? 1201 ATP   C C8    1 
HETATM 6550 N N7    . ATP   B 2 .    ? 143.193 89.357  103.483 1.00 14.65  ? 1201 ATP   C N7    1 
HETATM 6551 C C5    . ATP   B 2 .    ? 142.578 88.694  104.479 1.00 12.06  ? 1201 ATP   C C5    1 
HETATM 6552 C C6    . ATP   B 2 .    ? 142.200 89.022  105.812 1.00 16.85  ? 1201 ATP   C C6    1 
HETATM 6553 N N6    . ATP   B 2 .    ? 142.484 90.273  106.308 1.00 21.22  ? 1201 ATP   C N6    1 
HETATM 6554 N N1    . ATP   B 2 .    ? 141.563 88.096  106.561 1.00 21.86  ? 1201 ATP   C N1    1 
HETATM 6555 C C2    . ATP   B 2 .    ? 141.295 86.869  106.072 1.00 21.96  ? 1201 ATP   C C2    1 
HETATM 6556 N N3    . ATP   B 2 .    ? 141.640 86.516  104.822 1.00 15.93  ? 1201 ATP   C N3    1 
HETATM 6557 C C4    . ATP   B 2 .    ? 142.286 87.384  104.002 1.00 11.80  ? 1201 ATP   C C4    1 
HETATM 6558 N N1    . A1BLQ C 3 .    ? 160.214 95.444  94.758  1.00 0.50   ? 1202 A1BLQ C N1    1 
HETATM 6559 N N3    . A1BLQ C 3 .    ? 157.427 92.802  96.865  1.00 0.50   ? 1202 A1BLQ C N3    1 
HETATM 6560 C C4    . A1BLQ C 3 .    ? 160.383 95.910  97.623  1.00 0.50   ? 1202 A1BLQ C C4    1 
HETATM 6561 C C5    . A1BLQ C 3 .    ? 159.465 94.835  97.044  1.00 0.50   ? 1202 A1BLQ C C5    1 
HETATM 6562 C C6    . A1BLQ C 3 .    ? 159.041 95.241  95.618  1.00 0.50   ? 1202 A1BLQ C C6    1 
HETATM 6563 C C7    . A1BLQ C 3 .    ? 157.590 93.457  98.001  1.00 0.50   ? 1202 A1BLQ C C7    1 
HETATM 6564 C C8    . A1BLQ C 3 .    ? 156.119 91.194  97.885  1.00 0.50   ? 1202 A1BLQ C C8    1 
HETATM 6565 C C10   . A1BLQ C 3 .    ? 153.986 89.921  97.659  1.00 0.50   ? 1202 A1BLQ C C10   1 
HETATM 6566 C C13   . A1BLQ C 3 .    ? 155.356 87.623  96.998  1.00 0.50   ? 1202 A1BLQ C C13   1 
HETATM 6567 C C15   . A1BLQ C 3 .    ? 153.261 86.318  96.765  1.00 0.50   ? 1202 A1BLQ C C15   1 
HETATM 6568 C C17   . A1BLQ C 3 .    ? 155.559 91.248  100.352 1.00 0.50   ? 1202 A1BLQ C C17   1 
HETATM 6569 C C20   . A1BLQ C 3 .    ? 157.163 93.748  100.489 1.00 0.50   ? 1202 A1BLQ C C20   1 
HETATM 6570 C C21   . A1BLQ C 3 .    ? 156.979 93.005  99.187  1.00 0.50   ? 1202 A1BLQ C C21   1 
HETATM 6571 C C1    . A1BLQ C 3 .    ? 159.848 95.685  93.353  1.00 0.50   ? 1202 A1BLQ C C1    1 
HETATM 6572 C C2    . A1BLQ C 3 .    ? 161.068 96.523  95.301  1.00 0.50   ? 1202 A1BLQ C C2    1 
HETATM 6573 C C3    . A1BLQ C 3 .    ? 161.569 96.158  96.692  1.00 0.50   ? 1202 A1BLQ C C3    1 
HETATM 6574 N N2    . A1BLQ C 3 .    ? 158.313 94.619  97.916  1.00 0.50   ? 1202 A1BLQ C N2    1 
HETATM 6575 N N4    . A1BLQ C 3 .    ? 156.715 91.685  96.807  1.00 0.50   ? 1202 A1BLQ C N4    1 
HETATM 6576 C C9    . A1BLQ C 3 .    ? 155.371 89.948  97.625  1.00 0.50   ? 1202 A1BLQ C C9    1 
HETATM 6577 C C11   . A1BLQ C 3 .    ? 153.293 88.753  97.390  1.00 0.50   ? 1202 A1BLQ C C11   1 
HETATM 6578 C C12   . A1BLQ C 3 .    ? 153.973 87.596  97.053  1.00 0.50   ? 1202 A1BLQ C C12   1 
HETATM 6579 C C14   . A1BLQ C 3 .    ? 156.044 88.788  97.273  1.00 0.50   ? 1202 A1BLQ C C14   1 
HETATM 6580 O O1    . A1BLQ C 3 .    ? 157.406 88.832  97.212  1.00 0.50   ? 1202 A1BLQ C O1    1 
HETATM 6581 F F1    . A1BLQ C 3 .    ? 151.976 86.445  96.575  1.00 0.50   ? 1202 A1BLQ C F1    1 
HETATM 6582 F F2    . A1BLQ C 3 .    ? 153.390 85.436  97.721  1.00 0.50   ? 1202 A1BLQ C F2    1 
HETATM 6583 F F3    . A1BLQ C 3 .    ? 153.707 85.724  95.697  1.00 0.50   ? 1202 A1BLQ C F3    1 
HETATM 6584 C C16   . A1BLQ C 3 .    ? 156.237 91.823  99.125  1.00 0.50   ? 1202 A1BLQ C C16   1 
HETATM 6585 C C18   . A1BLQ C 3 .    ? 156.185 91.765  101.641 1.00 0.50   ? 1202 A1BLQ C C18   1 
HETATM 6586 C C19   . A1BLQ C 3 .    ? 156.225 93.274  101.597 1.00 0.50   ? 1202 A1BLQ C C19   1 
HETATM 6587 H H8    . A1BLQ C 3 .    ? 159.817 96.835  97.749  1.00 0.50   ? 1202 A1BLQ C H8    1 
HETATM 6588 H H9    . A1BLQ C 3 .    ? 160.733 95.608  98.613  1.00 0.50   ? 1202 A1BLQ C H9    1 
HETATM 6589 H H10   . A1BLQ C 3 .    ? 160.032 93.902  96.984  1.00 0.50   ? 1202 A1BLQ C H10   1 
HETATM 6590 H H11   . A1BLQ C 3 .    ? 158.410 94.466  95.181  1.00 0.50   ? 1202 A1BLQ C H11   1 
HETATM 6591 H H12   . A1BLQ C 3 .    ? 158.447 96.156  95.659  1.00 0.50   ? 1202 A1BLQ C H12   1 
HETATM 6592 H H14   . A1BLQ C 3 .    ? 153.442 90.822  97.925  1.00 0.50   ? 1202 A1BLQ C H14   1 
HETATM 6593 H H16   . A1BLQ C 3 .    ? 155.903 86.722  96.742  1.00 0.50   ? 1202 A1BLQ C H16   1 
HETATM 6594 H H19   . A1BLQ C 3 .    ? 155.620 90.159  100.330 1.00 0.50   ? 1202 A1BLQ C H19   1 
HETATM 6595 H H18   . A1BLQ C 3 .    ? 154.502 91.516  100.321 1.00 0.50   ? 1202 A1BLQ C H18   1 
HETATM 6596 H H25   . A1BLQ C 3 .    ? 157.011 94.816  100.322 1.00 0.50   ? 1202 A1BLQ C H25   1 
HETATM 6597 H H24   . A1BLQ C 3 .    ? 158.199 93.619  100.808 1.00 0.50   ? 1202 A1BLQ C H24   1 
HETATM 6598 H H3    . A1BLQ C 3 .    ? 159.264 96.601  93.267  1.00 0.50   ? 1202 A1BLQ C H3    1 
HETATM 6599 H H1    . A1BLQ C 3 .    ? 159.259 94.848  92.977  1.00 0.50   ? 1202 A1BLQ C H1    1 
HETATM 6600 H H2    . A1BLQ C 3 .    ? 160.749 95.777  92.747  1.00 0.50   ? 1202 A1BLQ C H2    1 
HETATM 6601 H H5    . A1BLQ C 3 .    ? 160.503 97.456  95.339  1.00 0.50   ? 1202 A1BLQ C H5    1 
HETATM 6602 H H4    . A1BLQ C 3 .    ? 161.917 96.682  94.632  1.00 0.50   ? 1202 A1BLQ C H4    1 
HETATM 6603 H H6    . A1BLQ C 3 .    ? 162.198 96.960  97.088  1.00 0.50   ? 1202 A1BLQ C H6    1 
HETATM 6604 H H7    . A1BLQ C 3 .    ? 162.186 95.259  96.637  1.00 0.50   ? 1202 A1BLQ C H7    1 
HETATM 6605 H H13   . A1BLQ C 3 .    ? 157.966 95.423  98.433  1.00 0.50   ? 1202 A1BLQ C H13   1 
HETATM 6606 H H15   . A1BLQ C 3 .    ? 152.211 88.757  97.449  1.00 0.50   ? 1202 A1BLQ C H15   1 
HETATM 6607 H H17   . A1BLQ C 3 .    ? 157.805 88.591  98.064  1.00 0.50   ? 1202 A1BLQ C H17   1 
HETATM 6608 H H20   . A1BLQ C 3 .    ? 157.199 91.372  101.748 1.00 0.50   ? 1202 A1BLQ C H20   1 
HETATM 6609 H H21   . A1BLQ C 3 .    ? 155.610 91.422  102.505 1.00 0.50   ? 1202 A1BLQ C H21   1 
HETATM 6610 H H23   . A1BLQ C 3 .    ? 155.217 93.658  101.420 1.00 0.50   ? 1202 A1BLQ C H23   1 
HETATM 6611 H H22   . A1BLQ C 3 .    ? 156.551 93.671  102.563 1.00 0.50   ? 1202 A1BLQ C H22   1 
# 
