data_9LYD
# 
_entry.id   9LYD 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9LYD         pdb_00009lyd 10.2210/pdb9lyd/pdb 
WWPDB D_1300056816 ?            ?                   
EMDB  EMD-63522    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-04-09 ? 
2 'Structure model' 1 1 2025-04-16 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.page_first'              
2 2 'Structure model' '_citation.page_last'               
3 2 'Structure model' '_citation.pdbx_database_id_PubMed' 
4 2 'Structure model' '_citation_author.identifier_ORCID' 
5 2 'Structure model' '_citation_author.name'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9LYD 
_pdbx_database_status.recvd_initial_deposition_date   2025-02-19 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        . 
_pdbx_database_related.db_id          EMD-63522 
_pdbx_database_related.content_type   'associated EM volume' 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
3 liuzhj@shanghaitech.edu.cn  ZJ   Liu ? 'principal investigator/group leader' 0000-0001-7279-2893 
4 huatian@shanghaitech.edu.cn Tian Hua ? 'principal investigator/group leader' 0000-0002-6132-2068 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Hua, T.'   1 0000-0002-6132-2068 
'Liu, Z.J.' 2 0000-0001-7279-2893 
'Li, X.T.'  3 0000-0001-6431-3143 
'Chang, H.' 4 0000-0003-1684-8201 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Cell Rep' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2211-1247 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            44 
_citation.language                  ? 
_citation.page_first                115478 
_citation.page_last                 115478 
_citation.title                     
'Structural basis of oligomerization-modulated activation and autoinhibition of orphan receptor GPR3.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.celrep.2025.115478 
_citation.pdbx_database_id_PubMed   40158220 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Chang, H.'  1 ? 
primary 'Li, X.'     2 ? 
primary 'Tu, H.'     3 ? 
primary 'Wu, L.'     4 ? 
primary 'Yu, Y.'     5 ? 
primary 'Liu, J.'    6 ? 
primary 'Chen, N.'   7 ? 
primary 'Shen, W.L.' 8 ? 
primary 'Hua, T.'    9 ? 
# 
_entity.id                         1 
_entity.type                       polymer 
_entity.src_method                 man 
_entity.pdbx_description           'G-protein coupled receptor 3,Aspartate racemase' 
_entity.formula_weight             52409.305 
_entity.pdbx_number_of_molecules   2 
_entity.pdbx_ec                    5.1.1.13 
_entity.pdbx_mutation              ? 
_entity.pdbx_fragment              ? 
_entity.details                    ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'ACCA orphan receptor' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;IIALSYIFCLVFADYKDDDDAGRAMMWGAGSPLAWLSAGSGNVNVSSVGPAEGPTGPAAPLPSPKAWDVVLCISGTLVSC
ENALVVAIIVGTPAFRAPMFLLVGSLAVADLLAGLGLVLHFAAVFCIGSAEMSLVLVGVLAMAFTASIGSLLAITVDRYL
SLYNALTYYSETTVTRTYVMLALVWGGALGLGLLPVLAWNCLDGLTTCGVVYPLSKNHLVVLAIAFFMVFGIMLQLYAQI
CRIVCRHAQQIALQRHLLPASHYVATRKGIATLAVVLGAFAACWLPFTVYCLLGDAHSPPLYTYLTLLPATYNSMINPII
YAFRNQDVQKVLWAVCCCCSSSKIPFRSRSPSDVEFLEVLFQGPHHHHHHHHHHMIEETAKKVKELGFKKAGLLATTGTI
VSGVYEKEFSKYGVEIMTPTEDEQKDVMRGIYEGVKAGNLKLGRELLLKTAKILEERGAECIIAGCTEVSVVLKQDDLKV
PLIDP
;
_entity_poly.pdbx_seq_one_letter_code_can   
;IIALSYIFCLVFADYKDDDDAGRAMMWGAGSPLAWLSAGSGNVNVSSVGPAEGPTGPAAPLPSPKAWDVVLCISGTLVSC
ENALVVAIIVGTPAFRAPMFLLVGSLAVADLLAGLGLVLHFAAVFCIGSAEMSLVLVGVLAMAFTASIGSLLAITVDRYL
SLYNALTYYSETTVTRTYVMLALVWGGALGLGLLPVLAWNCLDGLTTCGVVYPLSKNHLVVLAIAFFMVFGIMLQLYAQI
CRIVCRHAQQIALQRHLLPASHYVATRKGIATLAVVLGAFAACWLPFTVYCLLGDAHSPPLYTYLTLLPATYNSMINPII
YAFRNQDVQKVLWAVCCCCSSSKIPFRSRSPSDVEFLEVLFQGPHHHHHHHHHHMIEETAKKVKELGFKKAGLLATTGTI
VSGVYEKEFSKYGVEIMTPTEDEQKDVMRGIYEGVKAGNLKLGRELLLKTAKILEERGAECIIAGCTEVSVVLKQDDLKV
PLIDP
;
_entity_poly.pdbx_strand_id                 Q,R 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   ILE n 
1 2   ILE n 
1 3   ALA n 
1 4   LEU n 
1 5   SER n 
1 6   TYR n 
1 7   ILE n 
1 8   PHE n 
1 9   CYS n 
1 10  LEU n 
1 11  VAL n 
1 12  PHE n 
1 13  ALA n 
1 14  ASP n 
1 15  TYR n 
1 16  LYS n 
1 17  ASP n 
1 18  ASP n 
1 19  ASP n 
1 20  ASP n 
1 21  ALA n 
1 22  GLY n 
1 23  ARG n 
1 24  ALA n 
1 25  MET n 
1 26  MET n 
1 27  TRP n 
1 28  GLY n 
1 29  ALA n 
1 30  GLY n 
1 31  SER n 
1 32  PRO n 
1 33  LEU n 
1 34  ALA n 
1 35  TRP n 
1 36  LEU n 
1 37  SER n 
1 38  ALA n 
1 39  GLY n 
1 40  SER n 
1 41  GLY n 
1 42  ASN n 
1 43  VAL n 
1 44  ASN n 
1 45  VAL n 
1 46  SER n 
1 47  SER n 
1 48  VAL n 
1 49  GLY n 
1 50  PRO n 
1 51  ALA n 
1 52  GLU n 
1 53  GLY n 
1 54  PRO n 
1 55  THR n 
1 56  GLY n 
1 57  PRO n 
1 58  ALA n 
1 59  ALA n 
1 60  PRO n 
1 61  LEU n 
1 62  PRO n 
1 63  SER n 
1 64  PRO n 
1 65  LYS n 
1 66  ALA n 
1 67  TRP n 
1 68  ASP n 
1 69  VAL n 
1 70  VAL n 
1 71  LEU n 
1 72  CYS n 
1 73  ILE n 
1 74  SER n 
1 75  GLY n 
1 76  THR n 
1 77  LEU n 
1 78  VAL n 
1 79  SER n 
1 80  CYS n 
1 81  GLU n 
1 82  ASN n 
1 83  ALA n 
1 84  LEU n 
1 85  VAL n 
1 86  VAL n 
1 87  ALA n 
1 88  ILE n 
1 89  ILE n 
1 90  VAL n 
1 91  GLY n 
1 92  THR n 
1 93  PRO n 
1 94  ALA n 
1 95  PHE n 
1 96  ARG n 
1 97  ALA n 
1 98  PRO n 
1 99  MET n 
1 100 PHE n 
1 101 LEU n 
1 102 LEU n 
1 103 VAL n 
1 104 GLY n 
1 105 SER n 
1 106 LEU n 
1 107 ALA n 
1 108 VAL n 
1 109 ALA n 
1 110 ASP n 
1 111 LEU n 
1 112 LEU n 
1 113 ALA n 
1 114 GLY n 
1 115 LEU n 
1 116 GLY n 
1 117 LEU n 
1 118 VAL n 
1 119 LEU n 
1 120 HIS n 
1 121 PHE n 
1 122 ALA n 
1 123 ALA n 
1 124 VAL n 
1 125 PHE n 
1 126 CYS n 
1 127 ILE n 
1 128 GLY n 
1 129 SER n 
1 130 ALA n 
1 131 GLU n 
1 132 MET n 
1 133 SER n 
1 134 LEU n 
1 135 VAL n 
1 136 LEU n 
1 137 VAL n 
1 138 GLY n 
1 139 VAL n 
1 140 LEU n 
1 141 ALA n 
1 142 MET n 
1 143 ALA n 
1 144 PHE n 
1 145 THR n 
1 146 ALA n 
1 147 SER n 
1 148 ILE n 
1 149 GLY n 
1 150 SER n 
1 151 LEU n 
1 152 LEU n 
1 153 ALA n 
1 154 ILE n 
1 155 THR n 
1 156 VAL n 
1 157 ASP n 
1 158 ARG n 
1 159 TYR n 
1 160 LEU n 
1 161 SER n 
1 162 LEU n 
1 163 TYR n 
1 164 ASN n 
1 165 ALA n 
1 166 LEU n 
1 167 THR n 
1 168 TYR n 
1 169 TYR n 
1 170 SER n 
1 171 GLU n 
1 172 THR n 
1 173 THR n 
1 174 VAL n 
1 175 THR n 
1 176 ARG n 
1 177 THR n 
1 178 TYR n 
1 179 VAL n 
1 180 MET n 
1 181 LEU n 
1 182 ALA n 
1 183 LEU n 
1 184 VAL n 
1 185 TRP n 
1 186 GLY n 
1 187 GLY n 
1 188 ALA n 
1 189 LEU n 
1 190 GLY n 
1 191 LEU n 
1 192 GLY n 
1 193 LEU n 
1 194 LEU n 
1 195 PRO n 
1 196 VAL n 
1 197 LEU n 
1 198 ALA n 
1 199 TRP n 
1 200 ASN n 
1 201 CYS n 
1 202 LEU n 
1 203 ASP n 
1 204 GLY n 
1 205 LEU n 
1 206 THR n 
1 207 THR n 
1 208 CYS n 
1 209 GLY n 
1 210 VAL n 
1 211 VAL n 
1 212 TYR n 
1 213 PRO n 
1 214 LEU n 
1 215 SER n 
1 216 LYS n 
1 217 ASN n 
1 218 HIS n 
1 219 LEU n 
1 220 VAL n 
1 221 VAL n 
1 222 LEU n 
1 223 ALA n 
1 224 ILE n 
1 225 ALA n 
1 226 PHE n 
1 227 PHE n 
1 228 MET n 
1 229 VAL n 
1 230 PHE n 
1 231 GLY n 
1 232 ILE n 
1 233 MET n 
1 234 LEU n 
1 235 GLN n 
1 236 LEU n 
1 237 TYR n 
1 238 ALA n 
1 239 GLN n 
1 240 ILE n 
1 241 CYS n 
1 242 ARG n 
1 243 ILE n 
1 244 VAL n 
1 245 CYS n 
1 246 ARG n 
1 247 HIS n 
1 248 ALA n 
1 249 GLN n 
1 250 GLN n 
1 251 ILE n 
1 252 ALA n 
1 253 LEU n 
1 254 GLN n 
1 255 ARG n 
1 256 HIS n 
1 257 LEU n 
1 258 LEU n 
1 259 PRO n 
1 260 ALA n 
1 261 SER n 
1 262 HIS n 
1 263 TYR n 
1 264 VAL n 
1 265 ALA n 
1 266 THR n 
1 267 ARG n 
1 268 LYS n 
1 269 GLY n 
1 270 ILE n 
1 271 ALA n 
1 272 THR n 
1 273 LEU n 
1 274 ALA n 
1 275 VAL n 
1 276 VAL n 
1 277 LEU n 
1 278 GLY n 
1 279 ALA n 
1 280 PHE n 
1 281 ALA n 
1 282 ALA n 
1 283 CYS n 
1 284 TRP n 
1 285 LEU n 
1 286 PRO n 
1 287 PHE n 
1 288 THR n 
1 289 VAL n 
1 290 TYR n 
1 291 CYS n 
1 292 LEU n 
1 293 LEU n 
1 294 GLY n 
1 295 ASP n 
1 296 ALA n 
1 297 HIS n 
1 298 SER n 
1 299 PRO n 
1 300 PRO n 
1 301 LEU n 
1 302 TYR n 
1 303 THR n 
1 304 TYR n 
1 305 LEU n 
1 306 THR n 
1 307 LEU n 
1 308 LEU n 
1 309 PRO n 
1 310 ALA n 
1 311 THR n 
1 312 TYR n 
1 313 ASN n 
1 314 SER n 
1 315 MET n 
1 316 ILE n 
1 317 ASN n 
1 318 PRO n 
1 319 ILE n 
1 320 ILE n 
1 321 TYR n 
1 322 ALA n 
1 323 PHE n 
1 324 ARG n 
1 325 ASN n 
1 326 GLN n 
1 327 ASP n 
1 328 VAL n 
1 329 GLN n 
1 330 LYS n 
1 331 VAL n 
1 332 LEU n 
1 333 TRP n 
1 334 ALA n 
1 335 VAL n 
1 336 CYS n 
1 337 CYS n 
1 338 CYS n 
1 339 CYS n 
1 340 SER n 
1 341 SER n 
1 342 SER n 
1 343 LYS n 
1 344 ILE n 
1 345 PRO n 
1 346 PHE n 
1 347 ARG n 
1 348 SER n 
1 349 ARG n 
1 350 SER n 
1 351 PRO n 
1 352 SER n 
1 353 ASP n 
1 354 VAL n 
1 355 GLU n 
1 356 PHE n 
1 357 LEU n 
1 358 GLU n 
1 359 VAL n 
1 360 LEU n 
1 361 PHE n 
1 362 GLN n 
1 363 GLY n 
1 364 PRO n 
1 365 HIS n 
1 366 HIS n 
1 367 HIS n 
1 368 HIS n 
1 369 HIS n 
1 370 HIS n 
1 371 HIS n 
1 372 HIS n 
1 373 HIS n 
1 374 HIS n 
1 375 MET n 
1 376 ILE n 
1 377 GLU n 
1 378 GLU n 
1 379 THR n 
1 380 ALA n 
1 381 LYS n 
1 382 LYS n 
1 383 VAL n 
1 384 LYS n 
1 385 GLU n 
1 386 LEU n 
1 387 GLY n 
1 388 PHE n 
1 389 LYS n 
1 390 LYS n 
1 391 ALA n 
1 392 GLY n 
1 393 LEU n 
1 394 LEU n 
1 395 ALA n 
1 396 THR n 
1 397 THR n 
1 398 GLY n 
1 399 THR n 
1 400 ILE n 
1 401 VAL n 
1 402 SER n 
1 403 GLY n 
1 404 VAL n 
1 405 TYR n 
1 406 GLU n 
1 407 LYS n 
1 408 GLU n 
1 409 PHE n 
1 410 SER n 
1 411 LYS n 
1 412 TYR n 
1 413 GLY n 
1 414 VAL n 
1 415 GLU n 
1 416 ILE n 
1 417 MET n 
1 418 THR n 
1 419 PRO n 
1 420 THR n 
1 421 GLU n 
1 422 ASP n 
1 423 GLU n 
1 424 GLN n 
1 425 LYS n 
1 426 ASP n 
1 427 VAL n 
1 428 MET n 
1 429 ARG n 
1 430 GLY n 
1 431 ILE n 
1 432 TYR n 
1 433 GLU n 
1 434 GLY n 
1 435 VAL n 
1 436 LYS n 
1 437 ALA n 
1 438 GLY n 
1 439 ASN n 
1 440 LEU n 
1 441 LYS n 
1 442 LEU n 
1 443 GLY n 
1 444 ARG n 
1 445 GLU n 
1 446 LEU n 
1 447 LEU n 
1 448 LEU n 
1 449 LYS n 
1 450 THR n 
1 451 ALA n 
1 452 LYS n 
1 453 ILE n 
1 454 LEU n 
1 455 GLU n 
1 456 GLU n 
1 457 ARG n 
1 458 GLY n 
1 459 ALA n 
1 460 GLU n 
1 461 CYS n 
1 462 ILE n 
1 463 ILE n 
1 464 ALA n 
1 465 GLY n 
1 466 CYS n 
1 467 THR n 
1 468 GLU n 
1 469 VAL n 
1 470 SER n 
1 471 VAL n 
1 472 VAL n 
1 473 LEU n 
1 474 LYS n 
1 475 GLN n 
1 476 ASP n 
1 477 ASP n 
1 478 LEU n 
1 479 LYS n 
1 480 VAL n 
1 481 PRO n 
1 482 LEU n 
1 483 ILE n 
1 484 ASP n 
1 485 PRO n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1   354 human ? 'GPR3, ACCA' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
1 2 sample 'Biological sequence' 355 485 human ? PH0670       ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   ILE 1   -23  ?    ?   ?   Q . n 
A 1 2   ILE 2   -22  ?    ?   ?   Q . n 
A 1 3   ALA 3   -21  ?    ?   ?   Q . n 
A 1 4   LEU 4   -20  ?    ?   ?   Q . n 
A 1 5   SER 5   -19  ?    ?   ?   Q . n 
A 1 6   TYR 6   -18  ?    ?   ?   Q . n 
A 1 7   ILE 7   -17  ?    ?   ?   Q . n 
A 1 8   PHE 8   -16  ?    ?   ?   Q . n 
A 1 9   CYS 9   -15  ?    ?   ?   Q . n 
A 1 10  LEU 10  -14  ?    ?   ?   Q . n 
A 1 11  VAL 11  -13  ?    ?   ?   Q . n 
A 1 12  PHE 12  -12  ?    ?   ?   Q . n 
A 1 13  ALA 13  -11  ?    ?   ?   Q . n 
A 1 14  ASP 14  -10  ?    ?   ?   Q . n 
A 1 15  TYR 15  -9   ?    ?   ?   Q . n 
A 1 16  LYS 16  -8   ?    ?   ?   Q . n 
A 1 17  ASP 17  -7   ?    ?   ?   Q . n 
A 1 18  ASP 18  -6   ?    ?   ?   Q . n 
A 1 19  ASP 19  -5   ?    ?   ?   Q . n 
A 1 20  ASP 20  -4   ?    ?   ?   Q . n 
A 1 21  ALA 21  -3   ?    ?   ?   Q . n 
A 1 22  GLY 22  -2   ?    ?   ?   Q . n 
A 1 23  ARG 23  -1   ?    ?   ?   Q . n 
A 1 24  ALA 24  0    ?    ?   ?   Q . n 
A 1 25  MET 25  1    ?    ?   ?   Q . n 
A 1 26  MET 26  2    ?    ?   ?   Q . n 
A 1 27  TRP 27  3    ?    ?   ?   Q . n 
A 1 28  GLY 28  4    ?    ?   ?   Q . n 
A 1 29  ALA 29  5    ?    ?   ?   Q . n 
A 1 30  GLY 30  6    ?    ?   ?   Q . n 
A 1 31  SER 31  7    ?    ?   ?   Q . n 
A 1 32  PRO 32  8    ?    ?   ?   Q . n 
A 1 33  LEU 33  9    ?    ?   ?   Q . n 
A 1 34  ALA 34  10   ?    ?   ?   Q . n 
A 1 35  TRP 35  11   ?    ?   ?   Q . n 
A 1 36  LEU 36  12   ?    ?   ?   Q . n 
A 1 37  SER 37  13   ?    ?   ?   Q . n 
A 1 38  ALA 38  14   ?    ?   ?   Q . n 
A 1 39  GLY 39  15   ?    ?   ?   Q . n 
A 1 40  SER 40  16   ?    ?   ?   Q . n 
A 1 41  GLY 41  17   ?    ?   ?   Q . n 
A 1 42  ASN 42  18   ?    ?   ?   Q . n 
A 1 43  VAL 43  19   ?    ?   ?   Q . n 
A 1 44  ASN 44  20   ?    ?   ?   Q . n 
A 1 45  VAL 45  21   ?    ?   ?   Q . n 
A 1 46  SER 46  22   ?    ?   ?   Q . n 
A 1 47  SER 47  23   ?    ?   ?   Q . n 
A 1 48  VAL 48  24   ?    ?   ?   Q . n 
A 1 49  GLY 49  25   ?    ?   ?   Q . n 
A 1 50  PRO 50  26   ?    ?   ?   Q . n 
A 1 51  ALA 51  27   ?    ?   ?   Q . n 
A 1 52  GLU 52  28   ?    ?   ?   Q . n 
A 1 53  GLY 53  29   ?    ?   ?   Q . n 
A 1 54  PRO 54  30   ?    ?   ?   Q . n 
A 1 55  THR 55  31   ?    ?   ?   Q . n 
A 1 56  GLY 56  32   ?    ?   ?   Q . n 
A 1 57  PRO 57  33   ?    ?   ?   Q . n 
A 1 58  ALA 58  34   ?    ?   ?   Q . n 
A 1 59  ALA 59  35   35   ALA ALA Q . n 
A 1 60  PRO 60  36   36   PRO PRO Q . n 
A 1 61  LEU 61  37   37   LEU LEU Q . n 
A 1 62  PRO 62  38   38   PRO PRO Q . n 
A 1 63  SER 63  39   39   SER SER Q . n 
A 1 64  PRO 64  40   40   PRO PRO Q . n 
A 1 65  LYS 65  41   41   LYS LYS Q . n 
A 1 66  ALA 66  42   42   ALA ALA Q . n 
A 1 67  TRP 67  43   43   TRP TRP Q . n 
A 1 68  ASP 68  44   44   ASP ASP Q . n 
A 1 69  VAL 69  45   45   VAL VAL Q . n 
A 1 70  VAL 70  46   46   VAL VAL Q . n 
A 1 71  LEU 71  47   47   LEU LEU Q . n 
A 1 72  CYS 72  48   48   CYS CYS Q . n 
A 1 73  ILE 73  49   49   ILE ILE Q . n 
A 1 74  SER 74  50   50   SER SER Q . n 
A 1 75  GLY 75  51   51   GLY GLY Q . n 
A 1 76  THR 76  52   52   THR THR Q . n 
A 1 77  LEU 77  53   53   LEU LEU Q . n 
A 1 78  VAL 78  54   54   VAL VAL Q . n 
A 1 79  SER 79  55   55   SER SER Q . n 
A 1 80  CYS 80  56   56   CYS CYS Q . n 
A 1 81  GLU 81  57   57   GLU GLU Q . n 
A 1 82  ASN 82  58   58   ASN ASN Q . n 
A 1 83  ALA 83  59   59   ALA ALA Q . n 
A 1 84  LEU 84  60   60   LEU LEU Q . n 
A 1 85  VAL 85  61   61   VAL VAL Q . n 
A 1 86  VAL 86  62   62   VAL VAL Q . n 
A 1 87  ALA 87  63   63   ALA ALA Q . n 
A 1 88  ILE 88  64   64   ILE ILE Q . n 
A 1 89  ILE 89  65   65   ILE ILE Q . n 
A 1 90  VAL 90  66   66   VAL VAL Q . n 
A 1 91  GLY 91  67   67   GLY GLY Q . n 
A 1 92  THR 92  68   68   THR THR Q . n 
A 1 93  PRO 93  69   69   PRO PRO Q . n 
A 1 94  ALA 94  70   70   ALA ALA Q . n 
A 1 95  PHE 95  71   71   PHE PHE Q . n 
A 1 96  ARG 96  72   72   ARG ARG Q . n 
A 1 97  ALA 97  73   73   ALA ALA Q . n 
A 1 98  PRO 98  74   74   PRO PRO Q . n 
A 1 99  MET 99  75   75   MET MET Q . n 
A 1 100 PHE 100 76   76   PHE PHE Q . n 
A 1 101 LEU 101 77   77   LEU LEU Q . n 
A 1 102 LEU 102 78   78   LEU LEU Q . n 
A 1 103 VAL 103 79   79   VAL VAL Q . n 
A 1 104 GLY 104 80   80   GLY GLY Q . n 
A 1 105 SER 105 81   81   SER SER Q . n 
A 1 106 LEU 106 82   82   LEU LEU Q . n 
A 1 107 ALA 107 83   83   ALA ALA Q . n 
A 1 108 VAL 108 84   84   VAL VAL Q . n 
A 1 109 ALA 109 85   85   ALA ALA Q . n 
A 1 110 ASP 110 86   86   ASP ASP Q . n 
A 1 111 LEU 111 87   87   LEU LEU Q . n 
A 1 112 LEU 112 88   88   LEU LEU Q . n 
A 1 113 ALA 113 89   89   ALA ALA Q . n 
A 1 114 GLY 114 90   90   GLY GLY Q . n 
A 1 115 LEU 115 91   91   LEU LEU Q . n 
A 1 116 GLY 116 92   92   GLY GLY Q . n 
A 1 117 LEU 117 93   93   LEU LEU Q . n 
A 1 118 VAL 118 94   94   VAL VAL Q . n 
A 1 119 LEU 119 95   95   LEU LEU Q . n 
A 1 120 HIS 120 96   96   HIS HIS Q . n 
A 1 121 PHE 121 97   97   PHE PHE Q . n 
A 1 122 ALA 122 98   98   ALA ALA Q . n 
A 1 123 ALA 123 99   99   ALA ALA Q . n 
A 1 124 VAL 124 100  100  VAL VAL Q . n 
A 1 125 PHE 125 101  101  PHE PHE Q . n 
A 1 126 CYS 126 102  102  CYS CYS Q . n 
A 1 127 ILE 127 103  103  ILE ILE Q . n 
A 1 128 GLY 128 104  104  GLY GLY Q . n 
A 1 129 SER 129 105  105  SER SER Q . n 
A 1 130 ALA 130 106  106  ALA ALA Q . n 
A 1 131 GLU 131 107  107  GLU GLU Q . n 
A 1 132 MET 132 108  108  MET MET Q . n 
A 1 133 SER 133 109  109  SER SER Q . n 
A 1 134 LEU 134 110  110  LEU LEU Q . n 
A 1 135 VAL 135 111  111  VAL VAL Q . n 
A 1 136 LEU 136 112  112  LEU LEU Q . n 
A 1 137 VAL 137 113  113  VAL VAL Q . n 
A 1 138 GLY 138 114  114  GLY GLY Q . n 
A 1 139 VAL 139 115  115  VAL VAL Q . n 
A 1 140 LEU 140 116  116  LEU LEU Q . n 
A 1 141 ALA 141 117  117  ALA ALA Q . n 
A 1 142 MET 142 118  118  MET MET Q . n 
A 1 143 ALA 143 119  119  ALA ALA Q . n 
A 1 144 PHE 144 120  120  PHE PHE Q . n 
A 1 145 THR 145 121  121  THR THR Q . n 
A 1 146 ALA 146 122  122  ALA ALA Q . n 
A 1 147 SER 147 123  123  SER SER Q . n 
A 1 148 ILE 148 124  124  ILE ILE Q . n 
A 1 149 GLY 149 125  125  GLY GLY Q . n 
A 1 150 SER 150 126  126  SER SER Q . n 
A 1 151 LEU 151 127  127  LEU LEU Q . n 
A 1 152 LEU 152 128  128  LEU LEU Q . n 
A 1 153 ALA 153 129  129  ALA ALA Q . n 
A 1 154 ILE 154 130  130  ILE ILE Q . n 
A 1 155 THR 155 131  131  THR THR Q . n 
A 1 156 VAL 156 132  132  VAL VAL Q . n 
A 1 157 ASP 157 133  133  ASP ASP Q . n 
A 1 158 ARG 158 134  134  ARG ARG Q . n 
A 1 159 TYR 159 135  135  TYR TYR Q . n 
A 1 160 LEU 160 136  136  LEU LEU Q . n 
A 1 161 SER 161 137  137  SER SER Q . n 
A 1 162 LEU 162 138  138  LEU LEU Q . n 
A 1 163 TYR 163 139  139  TYR TYR Q . n 
A 1 164 ASN 164 140  140  ASN ASN Q . n 
A 1 165 ALA 165 141  141  ALA ALA Q . n 
A 1 166 LEU 166 142  142  LEU LEU Q . n 
A 1 167 THR 167 143  143  THR THR Q . n 
A 1 168 TYR 168 144  144  TYR TYR Q . n 
A 1 169 TYR 169 145  145  TYR TYR Q . n 
A 1 170 SER 170 146  146  SER SER Q . n 
A 1 171 GLU 171 147  147  GLU GLU Q . n 
A 1 172 THR 172 148  148  THR THR Q . n 
A 1 173 THR 173 149  149  THR THR Q . n 
A 1 174 VAL 174 150  150  VAL VAL Q . n 
A 1 175 THR 175 151  151  THR THR Q . n 
A 1 176 ARG 176 152  152  ARG ARG Q . n 
A 1 177 THR 177 153  153  THR THR Q . n 
A 1 178 TYR 178 154  154  TYR TYR Q . n 
A 1 179 VAL 179 155  155  VAL VAL Q . n 
A 1 180 MET 180 156  156  MET MET Q . n 
A 1 181 LEU 181 157  157  LEU LEU Q . n 
A 1 182 ALA 182 158  158  ALA ALA Q . n 
A 1 183 LEU 183 159  159  LEU LEU Q . n 
A 1 184 VAL 184 160  160  VAL VAL Q . n 
A 1 185 TRP 185 161  161  TRP TRP Q . n 
A 1 186 GLY 186 162  162  GLY GLY Q . n 
A 1 187 GLY 187 163  163  GLY GLY Q . n 
A 1 188 ALA 188 164  164  ALA ALA Q . n 
A 1 189 LEU 189 165  165  LEU LEU Q . n 
A 1 190 GLY 190 166  166  GLY GLY Q . n 
A 1 191 LEU 191 167  167  LEU LEU Q . n 
A 1 192 GLY 192 168  168  GLY GLY Q . n 
A 1 193 LEU 193 169  169  LEU LEU Q . n 
A 1 194 LEU 194 170  170  LEU LEU Q . n 
A 1 195 PRO 195 171  171  PRO PRO Q . n 
A 1 196 VAL 196 172  172  VAL VAL Q . n 
A 1 197 LEU 197 173  173  LEU LEU Q . n 
A 1 198 ALA 198 174  174  ALA ALA Q . n 
A 1 199 TRP 199 175  175  TRP TRP Q . n 
A 1 200 ASN 200 176  176  ASN ASN Q . n 
A 1 201 CYS 201 177  177  CYS CYS Q . n 
A 1 202 LEU 202 178  178  LEU LEU Q . n 
A 1 203 ASP 203 179  179  ASP ASP Q . n 
A 1 204 GLY 204 180  180  GLY GLY Q . n 
A 1 205 LEU 205 181  181  LEU LEU Q . n 
A 1 206 THR 206 182  182  THR THR Q . n 
A 1 207 THR 207 183  183  THR THR Q . n 
A 1 208 CYS 208 184  184  CYS CYS Q . n 
A 1 209 GLY 209 185  185  GLY GLY Q . n 
A 1 210 VAL 210 186  186  VAL VAL Q . n 
A 1 211 VAL 211 187  187  VAL VAL Q . n 
A 1 212 TYR 212 188  188  TYR TYR Q . n 
A 1 213 PRO 213 189  189  PRO PRO Q . n 
A 1 214 LEU 214 190  190  LEU LEU Q . n 
A 1 215 SER 215 191  191  SER SER Q . n 
A 1 216 LYS 216 192  192  LYS LYS Q . n 
A 1 217 ASN 217 193  193  ASN ASN Q . n 
A 1 218 HIS 218 194  194  HIS HIS Q . n 
A 1 219 LEU 219 195  195  LEU LEU Q . n 
A 1 220 VAL 220 196  196  VAL VAL Q . n 
A 1 221 VAL 221 197  197  VAL VAL Q . n 
A 1 222 LEU 222 198  198  LEU LEU Q . n 
A 1 223 ALA 223 199  199  ALA ALA Q . n 
A 1 224 ILE 224 200  200  ILE ILE Q . n 
A 1 225 ALA 225 201  201  ALA ALA Q . n 
A 1 226 PHE 226 202  202  PHE PHE Q . n 
A 1 227 PHE 227 203  203  PHE PHE Q . n 
A 1 228 MET 228 204  204  MET MET Q . n 
A 1 229 VAL 229 205  205  VAL VAL Q . n 
A 1 230 PHE 230 206  206  PHE PHE Q . n 
A 1 231 GLY 231 207  207  GLY GLY Q . n 
A 1 232 ILE 232 208  208  ILE ILE Q . n 
A 1 233 MET 233 209  209  MET MET Q . n 
A 1 234 LEU 234 210  210  LEU LEU Q . n 
A 1 235 GLN 235 211  211  GLN GLN Q . n 
A 1 236 LEU 236 212  212  LEU LEU Q . n 
A 1 237 TYR 237 213  213  TYR TYR Q . n 
A 1 238 ALA 238 214  214  ALA ALA Q . n 
A 1 239 GLN 239 215  215  GLN GLN Q . n 
A 1 240 ILE 240 216  216  ILE ILE Q . n 
A 1 241 CYS 241 217  217  CYS CYS Q . n 
A 1 242 ARG 242 218  218  ARG ARG Q . n 
A 1 243 ILE 243 219  219  ILE ILE Q . n 
A 1 244 VAL 244 220  220  VAL VAL Q . n 
A 1 245 CYS 245 221  221  CYS CYS Q . n 
A 1 246 ARG 246 222  222  ARG ARG Q . n 
A 1 247 HIS 247 223  223  HIS HIS Q . n 
A 1 248 ALA 248 224  224  ALA ALA Q . n 
A 1 249 GLN 249 225  ?    ?   ?   Q . n 
A 1 250 GLN 250 226  ?    ?   ?   Q . n 
A 1 251 ILE 251 227  ?    ?   ?   Q . n 
A 1 252 ALA 252 228  ?    ?   ?   Q . n 
A 1 253 LEU 253 229  ?    ?   ?   Q . n 
A 1 254 GLN 254 230  ?    ?   ?   Q . n 
A 1 255 ARG 255 231  ?    ?   ?   Q . n 
A 1 256 HIS 256 232  ?    ?   ?   Q . n 
A 1 257 LEU 257 233  ?    ?   ?   Q . n 
A 1 258 LEU 258 234  ?    ?   ?   Q . n 
A 1 259 PRO 259 235  ?    ?   ?   Q . n 
A 1 260 ALA 260 236  ?    ?   ?   Q . n 
A 1 261 SER 261 237  ?    ?   ?   Q . n 
A 1 262 HIS 262 238  ?    ?   ?   Q . n 
A 1 263 TYR 263 239  ?    ?   ?   Q . n 
A 1 264 VAL 264 240  ?    ?   ?   Q . n 
A 1 265 ALA 265 241  241  ALA ALA Q . n 
A 1 266 THR 266 242  242  THR THR Q . n 
A 1 267 ARG 267 243  243  ARG ARG Q . n 
A 1 268 LYS 268 244  244  LYS LYS Q . n 
A 1 269 GLY 269 245  245  GLY GLY Q . n 
A 1 270 ILE 270 246  246  ILE ILE Q . n 
A 1 271 ALA 271 247  247  ALA ALA Q . n 
A 1 272 THR 272 248  248  THR THR Q . n 
A 1 273 LEU 273 249  249  LEU LEU Q . n 
A 1 274 ALA 274 250  250  ALA ALA Q . n 
A 1 275 VAL 275 251  251  VAL VAL Q . n 
A 1 276 VAL 276 252  252  VAL VAL Q . n 
A 1 277 LEU 277 253  253  LEU LEU Q . n 
A 1 278 GLY 278 254  254  GLY GLY Q . n 
A 1 279 ALA 279 255  255  ALA ALA Q . n 
A 1 280 PHE 280 256  256  PHE PHE Q . n 
A 1 281 ALA 281 257  257  ALA ALA Q . n 
A 1 282 ALA 282 258  258  ALA ALA Q . n 
A 1 283 CYS 283 259  259  CYS CYS Q . n 
A 1 284 TRP 284 260  260  TRP TRP Q . n 
A 1 285 LEU 285 261  261  LEU LEU Q . n 
A 1 286 PRO 286 262  262  PRO PRO Q . n 
A 1 287 PHE 287 263  263  PHE PHE Q . n 
A 1 288 THR 288 264  264  THR THR Q . n 
A 1 289 VAL 289 265  265  VAL VAL Q . n 
A 1 290 TYR 290 266  266  TYR TYR Q . n 
A 1 291 CYS 291 267  267  CYS CYS Q . n 
A 1 292 LEU 292 268  268  LEU LEU Q . n 
A 1 293 LEU 293 269  269  LEU LEU Q . n 
A 1 294 GLY 294 270  270  GLY GLY Q . n 
A 1 295 ASP 295 271  271  ASP ASP Q . n 
A 1 296 ALA 296 272  272  ALA ALA Q . n 
A 1 297 HIS 297 273  273  HIS HIS Q . n 
A 1 298 SER 298 274  274  SER SER Q . n 
A 1 299 PRO 299 275  275  PRO PRO Q . n 
A 1 300 PRO 300 276  276  PRO PRO Q . n 
A 1 301 LEU 301 277  277  LEU LEU Q . n 
A 1 302 TYR 302 278  278  TYR TYR Q . n 
A 1 303 THR 303 279  279  THR THR Q . n 
A 1 304 TYR 304 280  280  TYR TYR Q . n 
A 1 305 LEU 305 281  281  LEU LEU Q . n 
A 1 306 THR 306 282  282  THR THR Q . n 
A 1 307 LEU 307 283  283  LEU LEU Q . n 
A 1 308 LEU 308 284  284  LEU LEU Q . n 
A 1 309 PRO 309 285  285  PRO PRO Q . n 
A 1 310 ALA 310 286  286  ALA ALA Q . n 
A 1 311 THR 311 287  287  THR THR Q . n 
A 1 312 TYR 312 288  288  TYR TYR Q . n 
A 1 313 ASN 313 289  289  ASN ASN Q . n 
A 1 314 SER 314 290  290  SER SER Q . n 
A 1 315 MET 315 291  291  MET MET Q . n 
A 1 316 ILE 316 292  292  ILE ILE Q . n 
A 1 317 ASN 317 293  293  ASN ASN Q . n 
A 1 318 PRO 318 294  294  PRO PRO Q . n 
A 1 319 ILE 319 295  295  ILE ILE Q . n 
A 1 320 ILE 320 296  296  ILE ILE Q . n 
A 1 321 TYR 321 297  297  TYR TYR Q . n 
A 1 322 ALA 322 298  298  ALA ALA Q . n 
A 1 323 PHE 323 299  299  PHE PHE Q . n 
A 1 324 ARG 324 300  300  ARG ARG Q . n 
A 1 325 ASN 325 301  301  ASN ASN Q . n 
A 1 326 GLN 326 302  302  GLN GLN Q . n 
A 1 327 ASP 327 303  303  ASP ASP Q . n 
A 1 328 VAL 328 304  304  VAL VAL Q . n 
A 1 329 GLN 329 305  305  GLN GLN Q . n 
A 1 330 LYS 330 306  306  LYS LYS Q . n 
A 1 331 VAL 331 307  307  VAL VAL Q . n 
A 1 332 LEU 332 308  308  LEU LEU Q . n 
A 1 333 TRP 333 309  309  TRP TRP Q . n 
A 1 334 ALA 334 310  310  ALA ALA Q . n 
A 1 335 VAL 335 311  311  VAL VAL Q . n 
A 1 336 CYS 336 312  312  CYS CYS Q . n 
A 1 337 CYS 337 963  ?    ?   ?   Q . n 
A 1 338 CYS 338 964  ?    ?   ?   Q . n 
A 1 339 CYS 339 965  ?    ?   ?   Q . n 
A 1 340 SER 340 966  ?    ?   ?   Q . n 
A 1 341 SER 341 967  ?    ?   ?   Q . n 
A 1 342 SER 342 968  ?    ?   ?   Q . n 
A 1 343 LYS 343 969  ?    ?   ?   Q . n 
A 1 344 ILE 344 970  ?    ?   ?   Q . n 
A 1 345 PRO 345 971  ?    ?   ?   Q . n 
A 1 346 PHE 346 972  ?    ?   ?   Q . n 
A 1 347 ARG 347 973  ?    ?   ?   Q . n 
A 1 348 SER 348 974  ?    ?   ?   Q . n 
A 1 349 ARG 349 975  ?    ?   ?   Q . n 
A 1 350 SER 350 976  ?    ?   ?   Q . n 
A 1 351 PRO 351 977  ?    ?   ?   Q . n 
A 1 352 SER 352 978  ?    ?   ?   Q . n 
A 1 353 ASP 353 979  ?    ?   ?   Q . n 
A 1 354 VAL 354 980  ?    ?   ?   Q . n 
A 1 355 GLU 355 981  ?    ?   ?   Q . n 
A 1 356 PHE 356 982  ?    ?   ?   Q . n 
A 1 357 LEU 357 983  ?    ?   ?   Q . n 
A 1 358 GLU 358 984  ?    ?   ?   Q . n 
A 1 359 VAL 359 985  ?    ?   ?   Q . n 
A 1 360 LEU 360 986  ?    ?   ?   Q . n 
A 1 361 PHE 361 987  ?    ?   ?   Q . n 
A 1 362 GLN 362 988  ?    ?   ?   Q . n 
A 1 363 GLY 363 989  ?    ?   ?   Q . n 
A 1 364 PRO 364 990  ?    ?   ?   Q . n 
A 1 365 HIS 365 991  ?    ?   ?   Q . n 
A 1 366 HIS 366 992  ?    ?   ?   Q . n 
A 1 367 HIS 367 993  ?    ?   ?   Q . n 
A 1 368 HIS 368 994  ?    ?   ?   Q . n 
A 1 369 HIS 369 995  ?    ?   ?   Q . n 
A 1 370 HIS 370 996  ?    ?   ?   Q . n 
A 1 371 HIS 371 997  ?    ?   ?   Q . n 
A 1 372 HIS 372 998  ?    ?   ?   Q . n 
A 1 373 HIS 373 999  ?    ?   ?   Q . n 
A 1 374 HIS 374 1000 ?    ?   ?   Q . n 
A 1 375 MET 375 1001 1001 MET MET Q . n 
A 1 376 ILE 376 1002 1002 ILE ILE Q . n 
A 1 377 GLU 377 1003 1003 GLU GLU Q . n 
A 1 378 GLU 378 1004 1004 GLU GLU Q . n 
A 1 379 THR 379 1005 1005 THR THR Q . n 
A 1 380 ALA 380 1006 1006 ALA ALA Q . n 
A 1 381 LYS 381 1007 1007 LYS LYS Q . n 
A 1 382 LYS 382 1008 1008 LYS LYS Q . n 
A 1 383 VAL 383 1009 1009 VAL VAL Q . n 
A 1 384 LYS 384 1010 1010 LYS LYS Q . n 
A 1 385 GLU 385 1011 1011 GLU GLU Q . n 
A 1 386 LEU 386 1012 1012 LEU LEU Q . n 
A 1 387 GLY 387 1013 1013 GLY GLY Q . n 
A 1 388 PHE 388 1014 1014 PHE PHE Q . n 
A 1 389 LYS 389 1015 1015 LYS LYS Q . n 
A 1 390 LYS 390 1016 1016 LYS LYS Q . n 
A 1 391 ALA 391 1017 1017 ALA ALA Q . n 
A 1 392 GLY 392 1018 1018 GLY GLY Q . n 
A 1 393 LEU 393 1019 1019 LEU LEU Q . n 
A 1 394 LEU 394 1020 1020 LEU LEU Q . n 
A 1 395 ALA 395 1021 1021 ALA ALA Q . n 
A 1 396 THR 396 1022 1022 THR THR Q . n 
A 1 397 THR 397 1023 1023 THR THR Q . n 
A 1 398 GLY 398 1024 1024 GLY GLY Q . n 
A 1 399 THR 399 1025 1025 THR THR Q . n 
A 1 400 ILE 400 1026 1026 ILE ILE Q . n 
A 1 401 VAL 401 1027 1027 VAL VAL Q . n 
A 1 402 SER 402 1028 1028 SER SER Q . n 
A 1 403 GLY 403 1029 1029 GLY GLY Q . n 
A 1 404 VAL 404 1030 1030 VAL VAL Q . n 
A 1 405 TYR 405 1031 1031 TYR TYR Q . n 
A 1 406 GLU 406 1032 1032 GLU GLU Q . n 
A 1 407 LYS 407 1033 1033 LYS LYS Q . n 
A 1 408 GLU 408 1034 1034 GLU GLU Q . n 
A 1 409 PHE 409 1035 1035 PHE PHE Q . n 
A 1 410 SER 410 1036 1036 SER SER Q . n 
A 1 411 LYS 411 1037 1037 LYS LYS Q . n 
A 1 412 TYR 412 1038 1038 TYR TYR Q . n 
A 1 413 GLY 413 1039 1039 GLY GLY Q . n 
A 1 414 VAL 414 1040 1040 VAL VAL Q . n 
A 1 415 GLU 415 1041 1041 GLU GLU Q . n 
A 1 416 ILE 416 1042 1042 ILE ILE Q . n 
A 1 417 MET 417 1043 1043 MET MET Q . n 
A 1 418 THR 418 1044 1044 THR THR Q . n 
A 1 419 PRO 419 1045 1045 PRO PRO Q . n 
A 1 420 THR 420 1046 1046 THR THR Q . n 
A 1 421 GLU 421 1047 1047 GLU GLU Q . n 
A 1 422 ASP 422 1048 1048 ASP ASP Q . n 
A 1 423 GLU 423 1049 1049 GLU GLU Q . n 
A 1 424 GLN 424 1050 1050 GLN GLN Q . n 
A 1 425 LYS 425 1051 1051 LYS LYS Q . n 
A 1 426 ASP 426 1052 1052 ASP ASP Q . n 
A 1 427 VAL 427 1053 1053 VAL VAL Q . n 
A 1 428 MET 428 1054 1054 MET MET Q . n 
A 1 429 ARG 429 1055 1055 ARG ARG Q . n 
A 1 430 GLY 430 1056 1056 GLY GLY Q . n 
A 1 431 ILE 431 1057 1057 ILE ILE Q . n 
A 1 432 TYR 432 1058 1058 TYR TYR Q . n 
A 1 433 GLU 433 1059 1059 GLU GLU Q . n 
A 1 434 GLY 434 1060 1060 GLY GLY Q . n 
A 1 435 VAL 435 1061 1061 VAL VAL Q . n 
A 1 436 LYS 436 1062 1062 LYS LYS Q . n 
A 1 437 ALA 437 1063 1063 ALA ALA Q . n 
A 1 438 GLY 438 1064 1064 GLY GLY Q . n 
A 1 439 ASN 439 1065 1065 ASN ASN Q . n 
A 1 440 LEU 440 1066 1066 LEU LEU Q . n 
A 1 441 LYS 441 1067 1067 LYS LYS Q . n 
A 1 442 LEU 442 1068 1068 LEU LEU Q . n 
A 1 443 GLY 443 1069 1069 GLY GLY Q . n 
A 1 444 ARG 444 1070 1070 ARG ARG Q . n 
A 1 445 GLU 445 1071 1071 GLU GLU Q . n 
A 1 446 LEU 446 1072 1072 LEU LEU Q . n 
A 1 447 LEU 447 1073 1073 LEU LEU Q . n 
A 1 448 LEU 448 1074 1074 LEU LEU Q . n 
A 1 449 LYS 449 1075 1075 LYS LYS Q . n 
A 1 450 THR 450 1076 1076 THR THR Q . n 
A 1 451 ALA 451 1077 1077 ALA ALA Q . n 
A 1 452 LYS 452 1078 1078 LYS LYS Q . n 
A 1 453 ILE 453 1079 1079 ILE ILE Q . n 
A 1 454 LEU 454 1080 1080 LEU LEU Q . n 
A 1 455 GLU 455 1081 1081 GLU GLU Q . n 
A 1 456 GLU 456 1082 1082 GLU GLU Q . n 
A 1 457 ARG 457 1083 1083 ARG ARG Q . n 
A 1 458 GLY 458 1084 1084 GLY GLY Q . n 
A 1 459 ALA 459 1085 1085 ALA ALA Q . n 
A 1 460 GLU 460 1086 1086 GLU GLU Q . n 
A 1 461 CYS 461 1087 1087 CYS CYS Q . n 
A 1 462 ILE 462 1088 1088 ILE ILE Q . n 
A 1 463 ILE 463 1089 1089 ILE ILE Q . n 
A 1 464 ALA 464 1090 1090 ALA ALA Q . n 
A 1 465 GLY 465 1091 1091 GLY GLY Q . n 
A 1 466 CYS 466 1092 1092 CYS CYS Q . n 
A 1 467 THR 467 1093 1093 THR THR Q . n 
A 1 468 GLU 468 1094 1094 GLU GLU Q . n 
A 1 469 VAL 469 1095 1095 VAL VAL Q . n 
A 1 470 SER 470 1096 1096 SER SER Q . n 
A 1 471 VAL 471 1097 1097 VAL VAL Q . n 
A 1 472 VAL 472 1098 1098 VAL VAL Q . n 
A 1 473 LEU 473 1099 1099 LEU LEU Q . n 
A 1 474 LYS 474 1100 1100 LYS LYS Q . n 
A 1 475 GLN 475 1101 1101 GLN GLN Q . n 
A 1 476 ASP 476 1102 1102 ASP ASP Q . n 
A 1 477 ASP 477 1103 1103 ASP ASP Q . n 
A 1 478 LEU 478 1104 1104 LEU LEU Q . n 
A 1 479 LYS 479 1105 1105 LYS LYS Q . n 
A 1 480 VAL 480 1106 1106 VAL VAL Q . n 
A 1 481 PRO 481 1107 1107 PRO PRO Q . n 
A 1 482 LEU 482 1108 1108 LEU LEU Q . n 
A 1 483 ILE 483 1109 1109 ILE ILE Q . n 
A 1 484 ASP 484 1110 1110 ASP ASP Q . n 
A 1 485 PRO 485 1111 1111 PRO PRO Q . n 
B 1 1   ILE 1   -23  ?    ?   ?   R . n 
B 1 2   ILE 2   -22  ?    ?   ?   R . n 
B 1 3   ALA 3   -21  ?    ?   ?   R . n 
B 1 4   LEU 4   -20  ?    ?   ?   R . n 
B 1 5   SER 5   -19  ?    ?   ?   R . n 
B 1 6   TYR 6   -18  ?    ?   ?   R . n 
B 1 7   ILE 7   -17  ?    ?   ?   R . n 
B 1 8   PHE 8   -16  ?    ?   ?   R . n 
B 1 9   CYS 9   -15  ?    ?   ?   R . n 
B 1 10  LEU 10  -14  ?    ?   ?   R . n 
B 1 11  VAL 11  -13  ?    ?   ?   R . n 
B 1 12  PHE 12  -12  ?    ?   ?   R . n 
B 1 13  ALA 13  -11  ?    ?   ?   R . n 
B 1 14  ASP 14  -10  ?    ?   ?   R . n 
B 1 15  TYR 15  -9   ?    ?   ?   R . n 
B 1 16  LYS 16  -8   ?    ?   ?   R . n 
B 1 17  ASP 17  -7   ?    ?   ?   R . n 
B 1 18  ASP 18  -6   ?    ?   ?   R . n 
B 1 19  ASP 19  -5   ?    ?   ?   R . n 
B 1 20  ASP 20  -4   ?    ?   ?   R . n 
B 1 21  ALA 21  -3   ?    ?   ?   R . n 
B 1 22  GLY 22  -2   ?    ?   ?   R . n 
B 1 23  ARG 23  -1   ?    ?   ?   R . n 
B 1 24  ALA 24  0    ?    ?   ?   R . n 
B 1 25  MET 25  1    ?    ?   ?   R . n 
B 1 26  MET 26  2    ?    ?   ?   R . n 
B 1 27  TRP 27  3    ?    ?   ?   R . n 
B 1 28  GLY 28  4    ?    ?   ?   R . n 
B 1 29  ALA 29  5    ?    ?   ?   R . n 
B 1 30  GLY 30  6    ?    ?   ?   R . n 
B 1 31  SER 31  7    ?    ?   ?   R . n 
B 1 32  PRO 32  8    ?    ?   ?   R . n 
B 1 33  LEU 33  9    ?    ?   ?   R . n 
B 1 34  ALA 34  10   ?    ?   ?   R . n 
B 1 35  TRP 35  11   ?    ?   ?   R . n 
B 1 36  LEU 36  12   ?    ?   ?   R . n 
B 1 37  SER 37  13   ?    ?   ?   R . n 
B 1 38  ALA 38  14   ?    ?   ?   R . n 
B 1 39  GLY 39  15   ?    ?   ?   R . n 
B 1 40  SER 40  16   ?    ?   ?   R . n 
B 1 41  GLY 41  17   ?    ?   ?   R . n 
B 1 42  ASN 42  18   ?    ?   ?   R . n 
B 1 43  VAL 43  19   ?    ?   ?   R . n 
B 1 44  ASN 44  20   ?    ?   ?   R . n 
B 1 45  VAL 45  21   ?    ?   ?   R . n 
B 1 46  SER 46  22   ?    ?   ?   R . n 
B 1 47  SER 47  23   ?    ?   ?   R . n 
B 1 48  VAL 48  24   ?    ?   ?   R . n 
B 1 49  GLY 49  25   ?    ?   ?   R . n 
B 1 50  PRO 50  26   ?    ?   ?   R . n 
B 1 51  ALA 51  27   ?    ?   ?   R . n 
B 1 52  GLU 52  28   ?    ?   ?   R . n 
B 1 53  GLY 53  29   ?    ?   ?   R . n 
B 1 54  PRO 54  30   ?    ?   ?   R . n 
B 1 55  THR 55  31   ?    ?   ?   R . n 
B 1 56  GLY 56  32   ?    ?   ?   R . n 
B 1 57  PRO 57  33   ?    ?   ?   R . n 
B 1 58  ALA 58  34   ?    ?   ?   R . n 
B 1 59  ALA 59  35   35   ALA ALA R . n 
B 1 60  PRO 60  36   36   PRO PRO R . n 
B 1 61  LEU 61  37   37   LEU LEU R . n 
B 1 62  PRO 62  38   38   PRO PRO R . n 
B 1 63  SER 63  39   39   SER SER R . n 
B 1 64  PRO 64  40   40   PRO PRO R . n 
B 1 65  LYS 65  41   41   LYS LYS R . n 
B 1 66  ALA 66  42   42   ALA ALA R . n 
B 1 67  TRP 67  43   43   TRP TRP R . n 
B 1 68  ASP 68  44   44   ASP ASP R . n 
B 1 69  VAL 69  45   45   VAL VAL R . n 
B 1 70  VAL 70  46   46   VAL VAL R . n 
B 1 71  LEU 71  47   47   LEU LEU R . n 
B 1 72  CYS 72  48   48   CYS CYS R . n 
B 1 73  ILE 73  49   49   ILE ILE R . n 
B 1 74  SER 74  50   50   SER SER R . n 
B 1 75  GLY 75  51   51   GLY GLY R . n 
B 1 76  THR 76  52   52   THR THR R . n 
B 1 77  LEU 77  53   53   LEU LEU R . n 
B 1 78  VAL 78  54   54   VAL VAL R . n 
B 1 79  SER 79  55   55   SER SER R . n 
B 1 80  CYS 80  56   56   CYS CYS R . n 
B 1 81  GLU 81  57   57   GLU GLU R . n 
B 1 82  ASN 82  58   58   ASN ASN R . n 
B 1 83  ALA 83  59   59   ALA ALA R . n 
B 1 84  LEU 84  60   60   LEU LEU R . n 
B 1 85  VAL 85  61   61   VAL VAL R . n 
B 1 86  VAL 86  62   62   VAL VAL R . n 
B 1 87  ALA 87  63   63   ALA ALA R . n 
B 1 88  ILE 88  64   64   ILE ILE R . n 
B 1 89  ILE 89  65   65   ILE ILE R . n 
B 1 90  VAL 90  66   66   VAL VAL R . n 
B 1 91  GLY 91  67   67   GLY GLY R . n 
B 1 92  THR 92  68   68   THR THR R . n 
B 1 93  PRO 93  69   69   PRO PRO R . n 
B 1 94  ALA 94  70   70   ALA ALA R . n 
B 1 95  PHE 95  71   71   PHE PHE R . n 
B 1 96  ARG 96  72   72   ARG ARG R . n 
B 1 97  ALA 97  73   73   ALA ALA R . n 
B 1 98  PRO 98  74   74   PRO PRO R . n 
B 1 99  MET 99  75   75   MET MET R . n 
B 1 100 PHE 100 76   76   PHE PHE R . n 
B 1 101 LEU 101 77   77   LEU LEU R . n 
B 1 102 LEU 102 78   78   LEU LEU R . n 
B 1 103 VAL 103 79   79   VAL VAL R . n 
B 1 104 GLY 104 80   80   GLY GLY R . n 
B 1 105 SER 105 81   81   SER SER R . n 
B 1 106 LEU 106 82   82   LEU LEU R . n 
B 1 107 ALA 107 83   83   ALA ALA R . n 
B 1 108 VAL 108 84   84   VAL VAL R . n 
B 1 109 ALA 109 85   85   ALA ALA R . n 
B 1 110 ASP 110 86   86   ASP ASP R . n 
B 1 111 LEU 111 87   87   LEU LEU R . n 
B 1 112 LEU 112 88   88   LEU LEU R . n 
B 1 113 ALA 113 89   89   ALA ALA R . n 
B 1 114 GLY 114 90   90   GLY GLY R . n 
B 1 115 LEU 115 91   91   LEU LEU R . n 
B 1 116 GLY 116 92   92   GLY GLY R . n 
B 1 117 LEU 117 93   93   LEU LEU R . n 
B 1 118 VAL 118 94   94   VAL VAL R . n 
B 1 119 LEU 119 95   95   LEU LEU R . n 
B 1 120 HIS 120 96   96   HIS HIS R . n 
B 1 121 PHE 121 97   97   PHE PHE R . n 
B 1 122 ALA 122 98   98   ALA ALA R . n 
B 1 123 ALA 123 99   99   ALA ALA R . n 
B 1 124 VAL 124 100  100  VAL VAL R . n 
B 1 125 PHE 125 101  101  PHE PHE R . n 
B 1 126 CYS 126 102  102  CYS CYS R . n 
B 1 127 ILE 127 103  103  ILE ILE R . n 
B 1 128 GLY 128 104  104  GLY GLY R . n 
B 1 129 SER 129 105  105  SER SER R . n 
B 1 130 ALA 130 106  106  ALA ALA R . n 
B 1 131 GLU 131 107  107  GLU GLU R . n 
B 1 132 MET 132 108  108  MET MET R . n 
B 1 133 SER 133 109  109  SER SER R . n 
B 1 134 LEU 134 110  110  LEU LEU R . n 
B 1 135 VAL 135 111  111  VAL VAL R . n 
B 1 136 LEU 136 112  112  LEU LEU R . n 
B 1 137 VAL 137 113  113  VAL VAL R . n 
B 1 138 GLY 138 114  114  GLY GLY R . n 
B 1 139 VAL 139 115  115  VAL VAL R . n 
B 1 140 LEU 140 116  116  LEU LEU R . n 
B 1 141 ALA 141 117  117  ALA ALA R . n 
B 1 142 MET 142 118  118  MET MET R . n 
B 1 143 ALA 143 119  119  ALA ALA R . n 
B 1 144 PHE 144 120  120  PHE PHE R . n 
B 1 145 THR 145 121  121  THR THR R . n 
B 1 146 ALA 146 122  122  ALA ALA R . n 
B 1 147 SER 147 123  123  SER SER R . n 
B 1 148 ILE 148 124  124  ILE ILE R . n 
B 1 149 GLY 149 125  125  GLY GLY R . n 
B 1 150 SER 150 126  126  SER SER R . n 
B 1 151 LEU 151 127  127  LEU LEU R . n 
B 1 152 LEU 152 128  128  LEU LEU R . n 
B 1 153 ALA 153 129  129  ALA ALA R . n 
B 1 154 ILE 154 130  130  ILE ILE R . n 
B 1 155 THR 155 131  131  THR THR R . n 
B 1 156 VAL 156 132  132  VAL VAL R . n 
B 1 157 ASP 157 133  133  ASP ASP R . n 
B 1 158 ARG 158 134  134  ARG ARG R . n 
B 1 159 TYR 159 135  135  TYR TYR R . n 
B 1 160 LEU 160 136  136  LEU LEU R . n 
B 1 161 SER 161 137  137  SER SER R . n 
B 1 162 LEU 162 138  138  LEU LEU R . n 
B 1 163 TYR 163 139  139  TYR TYR R . n 
B 1 164 ASN 164 140  140  ASN ASN R . n 
B 1 165 ALA 165 141  141  ALA ALA R . n 
B 1 166 LEU 166 142  142  LEU LEU R . n 
B 1 167 THR 167 143  143  THR THR R . n 
B 1 168 TYR 168 144  144  TYR TYR R . n 
B 1 169 TYR 169 145  145  TYR TYR R . n 
B 1 170 SER 170 146  146  SER SER R . n 
B 1 171 GLU 171 147  147  GLU GLU R . n 
B 1 172 THR 172 148  148  THR THR R . n 
B 1 173 THR 173 149  149  THR THR R . n 
B 1 174 VAL 174 150  150  VAL VAL R . n 
B 1 175 THR 175 151  151  THR THR R . n 
B 1 176 ARG 176 152  152  ARG ARG R . n 
B 1 177 THR 177 153  153  THR THR R . n 
B 1 178 TYR 178 154  154  TYR TYR R . n 
B 1 179 VAL 179 155  155  VAL VAL R . n 
B 1 180 MET 180 156  156  MET MET R . n 
B 1 181 LEU 181 157  157  LEU LEU R . n 
B 1 182 ALA 182 158  158  ALA ALA R . n 
B 1 183 LEU 183 159  159  LEU LEU R . n 
B 1 184 VAL 184 160  160  VAL VAL R . n 
B 1 185 TRP 185 161  161  TRP TRP R . n 
B 1 186 GLY 186 162  162  GLY GLY R . n 
B 1 187 GLY 187 163  163  GLY GLY R . n 
B 1 188 ALA 188 164  164  ALA ALA R . n 
B 1 189 LEU 189 165  165  LEU LEU R . n 
B 1 190 GLY 190 166  166  GLY GLY R . n 
B 1 191 LEU 191 167  167  LEU LEU R . n 
B 1 192 GLY 192 168  168  GLY GLY R . n 
B 1 193 LEU 193 169  169  LEU LEU R . n 
B 1 194 LEU 194 170  170  LEU LEU R . n 
B 1 195 PRO 195 171  171  PRO PRO R . n 
B 1 196 VAL 196 172  172  VAL VAL R . n 
B 1 197 LEU 197 173  173  LEU LEU R . n 
B 1 198 ALA 198 174  174  ALA ALA R . n 
B 1 199 TRP 199 175  175  TRP TRP R . n 
B 1 200 ASN 200 176  176  ASN ASN R . n 
B 1 201 CYS 201 177  177  CYS CYS R . n 
B 1 202 LEU 202 178  178  LEU LEU R . n 
B 1 203 ASP 203 179  179  ASP ASP R . n 
B 1 204 GLY 204 180  180  GLY GLY R . n 
B 1 205 LEU 205 181  181  LEU LEU R . n 
B 1 206 THR 206 182  182  THR THR R . n 
B 1 207 THR 207 183  183  THR THR R . n 
B 1 208 CYS 208 184  184  CYS CYS R . n 
B 1 209 GLY 209 185  185  GLY GLY R . n 
B 1 210 VAL 210 186  186  VAL VAL R . n 
B 1 211 VAL 211 187  187  VAL VAL R . n 
B 1 212 TYR 212 188  188  TYR TYR R . n 
B 1 213 PRO 213 189  189  PRO PRO R . n 
B 1 214 LEU 214 190  190  LEU LEU R . n 
B 1 215 SER 215 191  191  SER SER R . n 
B 1 216 LYS 216 192  192  LYS LYS R . n 
B 1 217 ASN 217 193  193  ASN ASN R . n 
B 1 218 HIS 218 194  194  HIS HIS R . n 
B 1 219 LEU 219 195  195  LEU LEU R . n 
B 1 220 VAL 220 196  196  VAL VAL R . n 
B 1 221 VAL 221 197  197  VAL VAL R . n 
B 1 222 LEU 222 198  198  LEU LEU R . n 
B 1 223 ALA 223 199  199  ALA ALA R . n 
B 1 224 ILE 224 200  200  ILE ILE R . n 
B 1 225 ALA 225 201  201  ALA ALA R . n 
B 1 226 PHE 226 202  202  PHE PHE R . n 
B 1 227 PHE 227 203  203  PHE PHE R . n 
B 1 228 MET 228 204  204  MET MET R . n 
B 1 229 VAL 229 205  205  VAL VAL R . n 
B 1 230 PHE 230 206  206  PHE PHE R . n 
B 1 231 GLY 231 207  207  GLY GLY R . n 
B 1 232 ILE 232 208  208  ILE ILE R . n 
B 1 233 MET 233 209  209  MET MET R . n 
B 1 234 LEU 234 210  210  LEU LEU R . n 
B 1 235 GLN 235 211  211  GLN GLN R . n 
B 1 236 LEU 236 212  212  LEU LEU R . n 
B 1 237 TYR 237 213  213  TYR TYR R . n 
B 1 238 ALA 238 214  214  ALA ALA R . n 
B 1 239 GLN 239 215  215  GLN GLN R . n 
B 1 240 ILE 240 216  216  ILE ILE R . n 
B 1 241 CYS 241 217  217  CYS CYS R . n 
B 1 242 ARG 242 218  218  ARG ARG R . n 
B 1 243 ILE 243 219  219  ILE ILE R . n 
B 1 244 VAL 244 220  220  VAL VAL R . n 
B 1 245 CYS 245 221  221  CYS CYS R . n 
B 1 246 ARG 246 222  222  ARG ARG R . n 
B 1 247 HIS 247 223  223  HIS HIS R . n 
B 1 248 ALA 248 224  224  ALA ALA R . n 
B 1 249 GLN 249 225  ?    ?   ?   R . n 
B 1 250 GLN 250 226  ?    ?   ?   R . n 
B 1 251 ILE 251 227  ?    ?   ?   R . n 
B 1 252 ALA 252 228  ?    ?   ?   R . n 
B 1 253 LEU 253 229  ?    ?   ?   R . n 
B 1 254 GLN 254 230  ?    ?   ?   R . n 
B 1 255 ARG 255 231  ?    ?   ?   R . n 
B 1 256 HIS 256 232  ?    ?   ?   R . n 
B 1 257 LEU 257 233  ?    ?   ?   R . n 
B 1 258 LEU 258 234  ?    ?   ?   R . n 
B 1 259 PRO 259 235  ?    ?   ?   R . n 
B 1 260 ALA 260 236  ?    ?   ?   R . n 
B 1 261 SER 261 237  ?    ?   ?   R . n 
B 1 262 HIS 262 238  ?    ?   ?   R . n 
B 1 263 TYR 263 239  ?    ?   ?   R . n 
B 1 264 VAL 264 240  ?    ?   ?   R . n 
B 1 265 ALA 265 241  241  ALA ALA R . n 
B 1 266 THR 266 242  242  THR THR R . n 
B 1 267 ARG 267 243  243  ARG ARG R . n 
B 1 268 LYS 268 244  244  LYS LYS R . n 
B 1 269 GLY 269 245  245  GLY GLY R . n 
B 1 270 ILE 270 246  246  ILE ILE R . n 
B 1 271 ALA 271 247  247  ALA ALA R . n 
B 1 272 THR 272 248  248  THR THR R . n 
B 1 273 LEU 273 249  249  LEU LEU R . n 
B 1 274 ALA 274 250  250  ALA ALA R . n 
B 1 275 VAL 275 251  251  VAL VAL R . n 
B 1 276 VAL 276 252  252  VAL VAL R . n 
B 1 277 LEU 277 253  253  LEU LEU R . n 
B 1 278 GLY 278 254  254  GLY GLY R . n 
B 1 279 ALA 279 255  255  ALA ALA R . n 
B 1 280 PHE 280 256  256  PHE PHE R . n 
B 1 281 ALA 281 257  257  ALA ALA R . n 
B 1 282 ALA 282 258  258  ALA ALA R . n 
B 1 283 CYS 283 259  259  CYS CYS R . n 
B 1 284 TRP 284 260  260  TRP TRP R . n 
B 1 285 LEU 285 261  261  LEU LEU R . n 
B 1 286 PRO 286 262  262  PRO PRO R . n 
B 1 287 PHE 287 263  263  PHE PHE R . n 
B 1 288 THR 288 264  264  THR THR R . n 
B 1 289 VAL 289 265  265  VAL VAL R . n 
B 1 290 TYR 290 266  266  TYR TYR R . n 
B 1 291 CYS 291 267  267  CYS CYS R . n 
B 1 292 LEU 292 268  268  LEU LEU R . n 
B 1 293 LEU 293 269  269  LEU LEU R . n 
B 1 294 GLY 294 270  270  GLY GLY R . n 
B 1 295 ASP 295 271  271  ASP ASP R . n 
B 1 296 ALA 296 272  272  ALA ALA R . n 
B 1 297 HIS 297 273  273  HIS HIS R . n 
B 1 298 SER 298 274  274  SER SER R . n 
B 1 299 PRO 299 275  275  PRO PRO R . n 
B 1 300 PRO 300 276  276  PRO PRO R . n 
B 1 301 LEU 301 277  277  LEU LEU R . n 
B 1 302 TYR 302 278  278  TYR TYR R . n 
B 1 303 THR 303 279  279  THR THR R . n 
B 1 304 TYR 304 280  280  TYR TYR R . n 
B 1 305 LEU 305 281  281  LEU LEU R . n 
B 1 306 THR 306 282  282  THR THR R . n 
B 1 307 LEU 307 283  283  LEU LEU R . n 
B 1 308 LEU 308 284  284  LEU LEU R . n 
B 1 309 PRO 309 285  285  PRO PRO R . n 
B 1 310 ALA 310 286  286  ALA ALA R . n 
B 1 311 THR 311 287  287  THR THR R . n 
B 1 312 TYR 312 288  288  TYR TYR R . n 
B 1 313 ASN 313 289  289  ASN ASN R . n 
B 1 314 SER 314 290  290  SER SER R . n 
B 1 315 MET 315 291  291  MET MET R . n 
B 1 316 ILE 316 292  292  ILE ILE R . n 
B 1 317 ASN 317 293  293  ASN ASN R . n 
B 1 318 PRO 318 294  294  PRO PRO R . n 
B 1 319 ILE 319 295  295  ILE ILE R . n 
B 1 320 ILE 320 296  296  ILE ILE R . n 
B 1 321 TYR 321 297  297  TYR TYR R . n 
B 1 322 ALA 322 298  298  ALA ALA R . n 
B 1 323 PHE 323 299  299  PHE PHE R . n 
B 1 324 ARG 324 300  300  ARG ARG R . n 
B 1 325 ASN 325 301  301  ASN ASN R . n 
B 1 326 GLN 326 302  302  GLN GLN R . n 
B 1 327 ASP 327 303  303  ASP ASP R . n 
B 1 328 VAL 328 304  304  VAL VAL R . n 
B 1 329 GLN 329 305  305  GLN GLN R . n 
B 1 330 LYS 330 306  306  LYS LYS R . n 
B 1 331 VAL 331 307  307  VAL VAL R . n 
B 1 332 LEU 332 308  308  LEU LEU R . n 
B 1 333 TRP 333 309  309  TRP TRP R . n 
B 1 334 ALA 334 310  310  ALA ALA R . n 
B 1 335 VAL 335 311  311  VAL VAL R . n 
B 1 336 CYS 336 312  312  CYS CYS R . n 
B 1 337 CYS 337 963  ?    ?   ?   R . n 
B 1 338 CYS 338 964  ?    ?   ?   R . n 
B 1 339 CYS 339 965  ?    ?   ?   R . n 
B 1 340 SER 340 966  ?    ?   ?   R . n 
B 1 341 SER 341 967  ?    ?   ?   R . n 
B 1 342 SER 342 968  ?    ?   ?   R . n 
B 1 343 LYS 343 969  ?    ?   ?   R . n 
B 1 344 ILE 344 970  ?    ?   ?   R . n 
B 1 345 PRO 345 971  ?    ?   ?   R . n 
B 1 346 PHE 346 972  ?    ?   ?   R . n 
B 1 347 ARG 347 973  ?    ?   ?   R . n 
B 1 348 SER 348 974  ?    ?   ?   R . n 
B 1 349 ARG 349 975  ?    ?   ?   R . n 
B 1 350 SER 350 976  ?    ?   ?   R . n 
B 1 351 PRO 351 977  ?    ?   ?   R . n 
B 1 352 SER 352 978  ?    ?   ?   R . n 
B 1 353 ASP 353 979  ?    ?   ?   R . n 
B 1 354 VAL 354 980  ?    ?   ?   R . n 
B 1 355 GLU 355 981  ?    ?   ?   R . n 
B 1 356 PHE 356 982  ?    ?   ?   R . n 
B 1 357 LEU 357 983  ?    ?   ?   R . n 
B 1 358 GLU 358 984  ?    ?   ?   R . n 
B 1 359 VAL 359 985  ?    ?   ?   R . n 
B 1 360 LEU 360 986  ?    ?   ?   R . n 
B 1 361 PHE 361 987  ?    ?   ?   R . n 
B 1 362 GLN 362 988  ?    ?   ?   R . n 
B 1 363 GLY 363 989  ?    ?   ?   R . n 
B 1 364 PRO 364 990  ?    ?   ?   R . n 
B 1 365 HIS 365 991  ?    ?   ?   R . n 
B 1 366 HIS 366 992  ?    ?   ?   R . n 
B 1 367 HIS 367 993  ?    ?   ?   R . n 
B 1 368 HIS 368 994  ?    ?   ?   R . n 
B 1 369 HIS 369 995  ?    ?   ?   R . n 
B 1 370 HIS 370 996  ?    ?   ?   R . n 
B 1 371 HIS 371 997  ?    ?   ?   R . n 
B 1 372 HIS 372 998  ?    ?   ?   R . n 
B 1 373 HIS 373 999  ?    ?   ?   R . n 
B 1 374 HIS 374 1000 ?    ?   ?   R . n 
B 1 375 MET 375 1001 1001 MET MET R . n 
B 1 376 ILE 376 1002 1002 ILE ILE R . n 
B 1 377 GLU 377 1003 1003 GLU GLU R . n 
B 1 378 GLU 378 1004 1004 GLU GLU R . n 
B 1 379 THR 379 1005 1005 THR THR R . n 
B 1 380 ALA 380 1006 1006 ALA ALA R . n 
B 1 381 LYS 381 1007 1007 LYS LYS R . n 
B 1 382 LYS 382 1008 1008 LYS LYS R . n 
B 1 383 VAL 383 1009 1009 VAL VAL R . n 
B 1 384 LYS 384 1010 1010 LYS LYS R . n 
B 1 385 GLU 385 1011 1011 GLU GLU R . n 
B 1 386 LEU 386 1012 1012 LEU LEU R . n 
B 1 387 GLY 387 1013 1013 GLY GLY R . n 
B 1 388 PHE 388 1014 1014 PHE PHE R . n 
B 1 389 LYS 389 1015 1015 LYS LYS R . n 
B 1 390 LYS 390 1016 1016 LYS LYS R . n 
B 1 391 ALA 391 1017 1017 ALA ALA R . n 
B 1 392 GLY 392 1018 1018 GLY GLY R . n 
B 1 393 LEU 393 1019 1019 LEU LEU R . n 
B 1 394 LEU 394 1020 1020 LEU LEU R . n 
B 1 395 ALA 395 1021 1021 ALA ALA R . n 
B 1 396 THR 396 1022 1022 THR THR R . n 
B 1 397 THR 397 1023 1023 THR THR R . n 
B 1 398 GLY 398 1024 1024 GLY GLY R . n 
B 1 399 THR 399 1025 1025 THR THR R . n 
B 1 400 ILE 400 1026 1026 ILE ILE R . n 
B 1 401 VAL 401 1027 1027 VAL VAL R . n 
B 1 402 SER 402 1028 1028 SER SER R . n 
B 1 403 GLY 403 1029 1029 GLY GLY R . n 
B 1 404 VAL 404 1030 1030 VAL VAL R . n 
B 1 405 TYR 405 1031 1031 TYR TYR R . n 
B 1 406 GLU 406 1032 1032 GLU GLU R . n 
B 1 407 LYS 407 1033 1033 LYS LYS R . n 
B 1 408 GLU 408 1034 1034 GLU GLU R . n 
B 1 409 PHE 409 1035 1035 PHE PHE R . n 
B 1 410 SER 410 1036 1036 SER SER R . n 
B 1 411 LYS 411 1037 1037 LYS LYS R . n 
B 1 412 TYR 412 1038 1038 TYR TYR R . n 
B 1 413 GLY 413 1039 1039 GLY GLY R . n 
B 1 414 VAL 414 1040 1040 VAL VAL R . n 
B 1 415 GLU 415 1041 1041 GLU GLU R . n 
B 1 416 ILE 416 1042 1042 ILE ILE R . n 
B 1 417 MET 417 1043 1043 MET MET R . n 
B 1 418 THR 418 1044 1044 THR THR R . n 
B 1 419 PRO 419 1045 1045 PRO PRO R . n 
B 1 420 THR 420 1046 1046 THR THR R . n 
B 1 421 GLU 421 1047 1047 GLU GLU R . n 
B 1 422 ASP 422 1048 1048 ASP ASP R . n 
B 1 423 GLU 423 1049 1049 GLU GLU R . n 
B 1 424 GLN 424 1050 1050 GLN GLN R . n 
B 1 425 LYS 425 1051 1051 LYS LYS R . n 
B 1 426 ASP 426 1052 1052 ASP ASP R . n 
B 1 427 VAL 427 1053 1053 VAL VAL R . n 
B 1 428 MET 428 1054 1054 MET MET R . n 
B 1 429 ARG 429 1055 1055 ARG ARG R . n 
B 1 430 GLY 430 1056 1056 GLY GLY R . n 
B 1 431 ILE 431 1057 1057 ILE ILE R . n 
B 1 432 TYR 432 1058 1058 TYR TYR R . n 
B 1 433 GLU 433 1059 1059 GLU GLU R . n 
B 1 434 GLY 434 1060 1060 GLY GLY R . n 
B 1 435 VAL 435 1061 1061 VAL VAL R . n 
B 1 436 LYS 436 1062 1062 LYS LYS R . n 
B 1 437 ALA 437 1063 1063 ALA ALA R . n 
B 1 438 GLY 438 1064 1064 GLY GLY R . n 
B 1 439 ASN 439 1065 1065 ASN ASN R . n 
B 1 440 LEU 440 1066 1066 LEU LEU R . n 
B 1 441 LYS 441 1067 1067 LYS LYS R . n 
B 1 442 LEU 442 1068 1068 LEU LEU R . n 
B 1 443 GLY 443 1069 1069 GLY GLY R . n 
B 1 444 ARG 444 1070 1070 ARG ARG R . n 
B 1 445 GLU 445 1071 1071 GLU GLU R . n 
B 1 446 LEU 446 1072 1072 LEU LEU R . n 
B 1 447 LEU 447 1073 1073 LEU LEU R . n 
B 1 448 LEU 448 1074 1074 LEU LEU R . n 
B 1 449 LYS 449 1075 1075 LYS LYS R . n 
B 1 450 THR 450 1076 1076 THR THR R . n 
B 1 451 ALA 451 1077 1077 ALA ALA R . n 
B 1 452 LYS 452 1078 1078 LYS LYS R . n 
B 1 453 ILE 453 1079 1079 ILE ILE R . n 
B 1 454 LEU 454 1080 1080 LEU LEU R . n 
B 1 455 GLU 455 1081 1081 GLU GLU R . n 
B 1 456 GLU 456 1082 1082 GLU GLU R . n 
B 1 457 ARG 457 1083 1083 ARG ARG R . n 
B 1 458 GLY 458 1084 1084 GLY GLY R . n 
B 1 459 ALA 459 1085 1085 ALA ALA R . n 
B 1 460 GLU 460 1086 1086 GLU GLU R . n 
B 1 461 CYS 461 1087 1087 CYS CYS R . n 
B 1 462 ILE 462 1088 1088 ILE ILE R . n 
B 1 463 ILE 463 1089 1089 ILE ILE R . n 
B 1 464 ALA 464 1090 1090 ALA ALA R . n 
B 1 465 GLY 465 1091 1091 GLY GLY R . n 
B 1 466 CYS 466 1092 1092 CYS CYS R . n 
B 1 467 THR 467 1093 1093 THR THR R . n 
B 1 468 GLU 468 1094 1094 GLU GLU R . n 
B 1 469 VAL 469 1095 1095 VAL VAL R . n 
B 1 470 SER 470 1096 1096 SER SER R . n 
B 1 471 VAL 471 1097 1097 VAL VAL R . n 
B 1 472 VAL 472 1098 1098 VAL VAL R . n 
B 1 473 LEU 473 1099 1099 LEU LEU R . n 
B 1 474 LYS 474 1100 1100 LYS LYS R . n 
B 1 475 GLN 475 1101 1101 GLN GLN R . n 
B 1 476 ASP 476 1102 1102 ASP ASP R . n 
B 1 477 ASP 477 1103 1103 ASP ASP R . n 
B 1 478 LEU 478 1104 1104 LEU LEU R . n 
B 1 479 LYS 479 1105 1105 LYS LYS R . n 
B 1 480 VAL 480 1106 1106 VAL VAL R . n 
B 1 481 PRO 481 1107 1107 PRO PRO R . n 
B 1 482 LEU 482 1108 1108 LEU LEU R . n 
B 1 483 ILE 483 1109 1109 ILE ILE R . n 
B 1 484 ASP 484 1110 1110 ASP ASP R . n 
B 1 485 PRO 485 1111 1111 PRO PRO R . n 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9LYD 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9LYD 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9LYD 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9LYD 
_struct.title                        'Cryo-EM structure of GPR3-1IU9 complex' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9LYD 
_struct_keywords.text            'GPCR, G protein, cryo-EM, membrane protein, STRUCTURAL PROTEIN' 
_struct_keywords.pdbx_keywords   'STRUCTURAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP GPR3_HUMAN P46089 ? 1 
;MMWGAGSPLAWLSAGSGNVNVSSVGPAEGPTGPAAPLPSPKAWDVVLCISGTLVSCENALVVAIIVGTPAFRAPMFLLVG
SLAVADLLAGLGLVLHFAAVFCIGSAEMSLVLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTRTYVMLALV
WGGALGLGLLPVLAWNCLDGLTTCGVVYPLSKNHLVVLAIAFFMVFGIMLQLYAQICRIVCRHAQQIALQRHLLPASHYV
ATRKGIATLAVVLGAFAACWLPFTVYCLLGDAHSPPLYTYLTLLPATYNSMINPIIYAFRNQDVQKVLWAVCCCCSSSKI
PFRSRSPSDV
;
1   
2 UNP RACD_PYRHO O58403 ? 1 
;MIEETAKKVKELGFKKAGLLATTGTIVSGVYEKEFSKYGVEIMTPTEDEQKDVMRGIYEGVKAGNLKLGRELLLKTAKIL
EERGAECIIAGCTEVSVVLKQDDLKVPLIDP
;
103 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9LYD Q 25  ? 354 ? P46089 1   ? 330 ? 1    980  
2 2 9LYD Q 375 ? 485 ? O58403 103 ? 213 ? 1001 1111 
3 1 9LYD R 25  ? 354 ? P46089 1   ? 330 ? 1    980  
4 2 9LYD R 375 ? 485 ? O58403 103 ? 213 ? 1001 1111 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9LYD ILE Q 1   ? UNP P46089 ? ? 'expression tag' -23  1  
1 9LYD ILE Q 2   ? UNP P46089 ? ? 'expression tag' -22  2  
1 9LYD ALA Q 3   ? UNP P46089 ? ? 'expression tag' -21  3  
1 9LYD LEU Q 4   ? UNP P46089 ? ? 'expression tag' -20  4  
1 9LYD SER Q 5   ? UNP P46089 ? ? 'expression tag' -19  5  
1 9LYD TYR Q 6   ? UNP P46089 ? ? 'expression tag' -18  6  
1 9LYD ILE Q 7   ? UNP P46089 ? ? 'expression tag' -17  7  
1 9LYD PHE Q 8   ? UNP P46089 ? ? 'expression tag' -16  8  
1 9LYD CYS Q 9   ? UNP P46089 ? ? 'expression tag' -15  9  
1 9LYD LEU Q 10  ? UNP P46089 ? ? 'expression tag' -14  10 
1 9LYD VAL Q 11  ? UNP P46089 ? ? 'expression tag' -13  11 
1 9LYD PHE Q 12  ? UNP P46089 ? ? 'expression tag' -12  12 
1 9LYD ALA Q 13  ? UNP P46089 ? ? 'expression tag' -11  13 
1 9LYD ASP Q 14  ? UNP P46089 ? ? 'expression tag' -10  14 
1 9LYD TYR Q 15  ? UNP P46089 ? ? 'expression tag' -9   15 
1 9LYD LYS Q 16  ? UNP P46089 ? ? 'expression tag' -8   16 
1 9LYD ASP Q 17  ? UNP P46089 ? ? 'expression tag' -7   17 
1 9LYD ASP Q 18  ? UNP P46089 ? ? 'expression tag' -6   18 
1 9LYD ASP Q 19  ? UNP P46089 ? ? 'expression tag' -5   19 
1 9LYD ASP Q 20  ? UNP P46089 ? ? 'expression tag' -4   20 
1 9LYD ALA Q 21  ? UNP P46089 ? ? 'expression tag' -3   21 
1 9LYD GLY Q 22  ? UNP P46089 ? ? 'expression tag' -2   22 
1 9LYD ARG Q 23  ? UNP P46089 ? ? 'expression tag' -1   23 
1 9LYD ALA Q 24  ? UNP P46089 ? ? 'expression tag' 0    24 
1 9LYD GLU Q 355 ? UNP P46089 ? ? linker           981  25 
1 9LYD PHE Q 356 ? UNP P46089 ? ? linker           982  26 
1 9LYD LEU Q 357 ? UNP P46089 ? ? linker           983  27 
1 9LYD GLU Q 358 ? UNP P46089 ? ? linker           984  28 
1 9LYD VAL Q 359 ? UNP P46089 ? ? linker           985  29 
1 9LYD LEU Q 360 ? UNP P46089 ? ? linker           986  30 
1 9LYD PHE Q 361 ? UNP P46089 ? ? linker           987  31 
1 9LYD GLN Q 362 ? UNP P46089 ? ? linker           988  32 
1 9LYD GLY Q 363 ? UNP P46089 ? ? linker           989  33 
1 9LYD PRO Q 364 ? UNP P46089 ? ? linker           990  34 
1 9LYD HIS Q 365 ? UNP P46089 ? ? linker           991  35 
1 9LYD HIS Q 366 ? UNP P46089 ? ? linker           992  36 
1 9LYD HIS Q 367 ? UNP P46089 ? ? linker           993  37 
1 9LYD HIS Q 368 ? UNP P46089 ? ? linker           994  38 
1 9LYD HIS Q 369 ? UNP P46089 ? ? linker           995  39 
1 9LYD HIS Q 370 ? UNP P46089 ? ? linker           996  40 
1 9LYD HIS Q 371 ? UNP P46089 ? ? linker           997  41 
1 9LYD HIS Q 372 ? UNP P46089 ? ? linker           998  42 
1 9LYD HIS Q 373 ? UNP P46089 ? ? linker           999  43 
1 9LYD HIS Q 374 ? UNP P46089 ? ? linker           1000 44 
3 9LYD ILE R 1   ? UNP P46089 ? ? 'expression tag' -23  45 
3 9LYD ILE R 2   ? UNP P46089 ? ? 'expression tag' -22  46 
3 9LYD ALA R 3   ? UNP P46089 ? ? 'expression tag' -21  47 
3 9LYD LEU R 4   ? UNP P46089 ? ? 'expression tag' -20  48 
3 9LYD SER R 5   ? UNP P46089 ? ? 'expression tag' -19  49 
3 9LYD TYR R 6   ? UNP P46089 ? ? 'expression tag' -18  50 
3 9LYD ILE R 7   ? UNP P46089 ? ? 'expression tag' -17  51 
3 9LYD PHE R 8   ? UNP P46089 ? ? 'expression tag' -16  52 
3 9LYD CYS R 9   ? UNP P46089 ? ? 'expression tag' -15  53 
3 9LYD LEU R 10  ? UNP P46089 ? ? 'expression tag' -14  54 
3 9LYD VAL R 11  ? UNP P46089 ? ? 'expression tag' -13  55 
3 9LYD PHE R 12  ? UNP P46089 ? ? 'expression tag' -12  56 
3 9LYD ALA R 13  ? UNP P46089 ? ? 'expression tag' -11  57 
3 9LYD ASP R 14  ? UNP P46089 ? ? 'expression tag' -10  58 
3 9LYD TYR R 15  ? UNP P46089 ? ? 'expression tag' -9   59 
3 9LYD LYS R 16  ? UNP P46089 ? ? 'expression tag' -8   60 
3 9LYD ASP R 17  ? UNP P46089 ? ? 'expression tag' -7   61 
3 9LYD ASP R 18  ? UNP P46089 ? ? 'expression tag' -6   62 
3 9LYD ASP R 19  ? UNP P46089 ? ? 'expression tag' -5   63 
3 9LYD ASP R 20  ? UNP P46089 ? ? 'expression tag' -4   64 
3 9LYD ALA R 21  ? UNP P46089 ? ? 'expression tag' -3   65 
3 9LYD GLY R 22  ? UNP P46089 ? ? 'expression tag' -2   66 
3 9LYD ARG R 23  ? UNP P46089 ? ? 'expression tag' -1   67 
3 9LYD ALA R 24  ? UNP P46089 ? ? 'expression tag' 0    68 
3 9LYD GLU R 355 ? UNP P46089 ? ? linker           981  69 
3 9LYD PHE R 356 ? UNP P46089 ? ? linker           982  70 
3 9LYD LEU R 357 ? UNP P46089 ? ? linker           983  71 
3 9LYD GLU R 358 ? UNP P46089 ? ? linker           984  72 
3 9LYD VAL R 359 ? UNP P46089 ? ? linker           985  73 
3 9LYD LEU R 360 ? UNP P46089 ? ? linker           986  74 
3 9LYD PHE R 361 ? UNP P46089 ? ? linker           987  75 
3 9LYD GLN R 362 ? UNP P46089 ? ? linker           988  76 
3 9LYD GLY R 363 ? UNP P46089 ? ? linker           989  77 
3 9LYD PRO R 364 ? UNP P46089 ? ? linker           990  78 
3 9LYD HIS R 365 ? UNP P46089 ? ? linker           991  79 
3 9LYD HIS R 366 ? UNP P46089 ? ? linker           992  80 
3 9LYD HIS R 367 ? UNP P46089 ? ? linker           993  81 
3 9LYD HIS R 368 ? UNP P46089 ? ? linker           994  82 
3 9LYD HIS R 369 ? UNP P46089 ? ? linker           995  83 
3 9LYD HIS R 370 ? UNP P46089 ? ? linker           996  84 
3 9LYD HIS R 371 ? UNP P46089 ? ? linker           997  85 
3 9LYD HIS R 372 ? UNP P46089 ? ? linker           998  86 
3 9LYD HIS R 373 ? UNP P46089 ? ? linker           999  87 
3 9LYD HIS R 374 ? UNP P46089 ? ? linker           1000 88 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 LYS A 65  ? THR A 92  ? LYS Q 41   THR Q 68   1 ? 28 
HELX_P HELX_P2  AA2 ALA A 97  ? VAL A 124 ? ALA Q 73   VAL Q 100  1 ? 28 
HELX_P HELX_P3  AA3 ALA A 130 ? TYR A 168 ? ALA Q 106  TYR Q 144  1 ? 39 
HELX_P HELX_P4  AA4 ARG A 176 ? GLY A 186 ? ARG Q 152  GLY Q 162  1 ? 11 
HELX_P HELX_P5  AA5 GLY A 186 ? ALA A 198 ? GLY Q 162  ALA Q 174  1 ? 13 
HELX_P HELX_P6  AA6 SER A 215 ? HIS A 247 ? SER Q 191  HIS Q 223  1 ? 33 
HELX_P HELX_P7  AA7 THR A 266 ? LEU A 273 ? THR Q 242  LEU Q 249  1 ? 8  
HELX_P HELX_P8  AA8 ALA A 274 ? GLY A 294 ? ALA Q 250  GLY Q 270  1 ? 21 
HELX_P HELX_P9  AA9 PRO A 300 ? ALA A 322 ? PRO Q 276  ALA Q 298  1 ? 23 
HELX_P HELX_P10 AB1 ASN A 325 ? CYS A 336 ? ASN Q 301  CYS Q 312  1 ? 12 
HELX_P HELX_P11 AB2 ILE A 376 ? LEU A 386 ? ILE Q 1002 LEU Q 1012 1 ? 11 
HELX_P HELX_P12 AB3 THR A 396 ? GLY A 403 ? THR Q 1022 GLY Q 1029 1 ? 8  
HELX_P HELX_P13 AB4 GLY A 403 ? LYS A 411 ? GLY Q 1029 LYS Q 1037 1 ? 9  
HELX_P HELX_P14 AB5 THR A 420 ? TYR A 432 ? THR Q 1046 TYR Q 1058 1 ? 13 
HELX_P HELX_P15 AB6 ASN A 439 ? ARG A 457 ? ASN Q 1065 ARG Q 1083 1 ? 19 
HELX_P HELX_P16 AB7 CYS A 466 ? LEU A 473 ? CYS Q 1092 LEU Q 1099 1 ? 8  
HELX_P HELX_P17 AB8 LYS A 474 ? LEU A 478 ? LYS Q 1100 LEU Q 1104 5 ? 5  
HELX_P HELX_P18 AB9 LYS B 65  ? THR B 92  ? LYS R 41   THR R 68   1 ? 28 
HELX_P HELX_P19 AC1 ALA B 97  ? VAL B 124 ? ALA R 73   VAL R 100  1 ? 28 
HELX_P HELX_P20 AC2 ALA B 130 ? ASN B 164 ? ALA R 106  ASN R 140  1 ? 35 
HELX_P HELX_P21 AC3 GLU B 171 ? GLY B 192 ? GLU R 147  GLY R 168  1 ? 22 
HELX_P HELX_P22 AC4 GLY B 192 ? LEU B 197 ? GLY R 168  LEU R 173  1 ? 6  
HELX_P HELX_P23 AC5 SER B 215 ? CYS B 245 ? SER R 191  CYS R 221  1 ? 31 
HELX_P HELX_P24 AC6 THR B 266 ? TRP B 284 ? THR R 242  TRP R 260  1 ? 19 
HELX_P HELX_P25 AC7 PRO B 286 ? CYS B 291 ? PRO R 262  CYS R 267  1 ? 6  
HELX_P HELX_P26 AC8 PRO B 300 ? LEU B 307 ? PRO R 276  LEU R 283  1 ? 8  
HELX_P HELX_P27 AC9 LEU B 307 ? TYR B 321 ? LEU R 283  TYR R 297  1 ? 15 
HELX_P HELX_P28 AD1 ASN B 325 ? CYS B 336 ? ASN R 301  CYS R 312  1 ? 12 
HELX_P HELX_P29 AD2 ILE B 376 ? GLY B 387 ? ILE R 1002 GLY R 1013 1 ? 12 
HELX_P HELX_P30 AD3 THR B 396 ? GLY B 403 ? THR R 1022 GLY R 1029 1 ? 8  
HELX_P HELX_P31 AD4 GLY B 403 ? LYS B 411 ? GLY R 1029 LYS R 1037 1 ? 9  
HELX_P HELX_P32 AD5 THR B 420 ? TYR B 432 ? THR R 1046 TYR R 1058 1 ? 13 
HELX_P HELX_P33 AD6 ASN B 439 ? ARG B 457 ? ASN R 1065 ARG R 1083 1 ? 19 
HELX_P HELX_P34 AD7 CYS B 466 ? LEU B 473 ? CYS R 1092 LEU R 1099 1 ? 8  
HELX_P HELX_P35 AD8 LYS B 474 ? LEU B 478 ? LYS R 1100 LEU R 1104 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 201 SG ? ? ? 1_555 A CYS 208 SG ? ? Q CYS 177 Q CYS 184 1_555 ? ? ? ? ? ? ? 2.032 ? ? 
disulf2 disulf ? ? B CYS 201 SG ? ? ? 1_555 B CYS 208 SG ? ? R CYS 177 R CYS 184 1_555 ? ? ? ? ? ? ? 2.032 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 201 ? CYS A 208 ? CYS Q 177 ? 1_555 CYS Q 184 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS B 201 ? CYS B 208 ? CYS R 177 ? 1_555 CYS R 184 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 TYR 212 A . ? TYR 188 Q PRO 213 A ? PRO 189 Q 1 -3.85 
2 TYR 212 B . ? TYR 188 R PRO 213 B ? PRO 189 R 1 -4.82 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel 
AA1 2 3 ? parallel 
AA1 3 4 ? parallel 
AA2 1 2 ? parallel 
AA2 2 3 ? parallel 
AA2 3 4 ? parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLU A 415 ? MET A 417 ? GLU Q 1041 MET Q 1043 
AA1 2 LYS A 390 ? LEU A 394 ? LYS Q 1016 LEU Q 1020 
AA1 3 ILE A 462 ? ALA A 464 ? ILE Q 1088 ALA Q 1090 
AA1 4 LEU A 482 ? ILE A 483 ? LEU Q 1108 ILE Q 1109 
AA2 1 GLU B 415 ? MET B 417 ? GLU R 1041 MET R 1043 
AA2 2 LYS B 390 ? LEU B 394 ? LYS R 1016 LEU R 1020 
AA2 3 ILE B 462 ? ALA B 464 ? ILE R 1088 ALA R 1090 
AA2 4 LEU B 482 ? ILE B 483 ? LEU R 1108 ILE R 1109 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O GLU A 415 ? O GLU Q 1041 N ALA A 391 ? N ALA Q 1017 
AA1 2 3 N GLY A 392 ? N GLY Q 1018 O ILE A 463 ? O ILE Q 1089 
AA1 3 4 N ILE A 462 ? N ILE Q 1088 O ILE A 483 ? O ILE Q 1109 
AA2 1 2 O GLU B 415 ? O GLU R 1041 N ALA B 391 ? N ALA R 1017 
AA2 2 3 N GLY B 392 ? N GLY R 1018 O ILE B 463 ? O ILE R 1089 
AA2 3 4 N ILE B 462 ? N ILE R 1088 O ILE B 483 ? O ILE R 1109 
# 
_pdbx_entry_details.entry_id                   9LYD 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 C   Q ALA 224 ? ? N  Q MET 1001 ? ? 1.33 
2 1 C   R ALA 224 ? ? N  R MET 1001 ? ? 1.33 
3 1 OE1 Q GLN 215 ? ? OH R TYR 135  ? ? 2.19 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 C  R LEU 261  ? ? N  R PRO 262  ? ? CD R PRO 262  ? ? 113.35 128.40 -15.05 2.10 Y 
2 1 CA R LEU 1074 ? ? CB R LEU 1074 ? ? CG R LEU 1074 ? ? 130.82 115.30 15.52  2.30 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 PHE Q 71  ? ? -96.58  58.57  
2 1 ILE Q 103 ? ? -126.83 -51.86 
3 1 THR Q 148 ? ? 69.13   145.79 
4 1 HIS Q 223 ? ? -87.78  47.62  
5 1 PHE R 71  ? ? -95.60  54.86  
6 1 LEU R 173 ? ? -87.73  46.09  
7 1 ALA R 174 ? ? 179.98  168.87 
8 1 CYS R 221 ? ? -91.99  48.84  
# 
_pdbx_validate_peptide_omega.id               1 
_pdbx_validate_peptide_omega.PDB_model_num    1 
_pdbx_validate_peptide_omega.auth_comp_id_1   LEU 
_pdbx_validate_peptide_omega.auth_asym_id_1   R 
_pdbx_validate_peptide_omega.auth_seq_id_1    261 
_pdbx_validate_peptide_omega.PDB_ins_code_1   ? 
_pdbx_validate_peptide_omega.label_alt_id_1   ? 
_pdbx_validate_peptide_omega.auth_comp_id_2   PRO 
_pdbx_validate_peptide_omega.auth_asym_id_2   R 
_pdbx_validate_peptide_omega.auth_seq_id_2    262 
_pdbx_validate_peptide_omega.PDB_ins_code_2   ? 
_pdbx_validate_peptide_omega.label_alt_id_2   ? 
_pdbx_validate_peptide_omega.omega            147.62 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9LYD 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   118.6 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      'RIGID BODY FIT' 
# 
_em_3d_reconstruction.entry_id                    9LYD 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.66 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               205789 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'dimer state of GPR3 with PGS' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9LYD 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TECNAI ARCTICA' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            50 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
_em_imaging.objective_aperture              ? 
_em_imaging.microscope_serial_number        ? 
_em_imaging.microscope_version              ? 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    'GRAPHENE OXIDE' 
_em_sample_support.grid_mesh_size   400 
_em_sample_support.grid_type        'Quantifoil R1.2/1.3' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              9LYD 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            'FEI VITROBOT MARK IV' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9LYD 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
_em_single_particle_entity.entry_id              9LYD 
_em_single_particle_entity.id                    1 
_em_single_particle_entity.image_processing_id   1 
_em_single_particle_entity.point_symmetry        C1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 Q ILE -23  ? A ILE 1   
2   1 Y 1 Q ILE -22  ? A ILE 2   
3   1 Y 1 Q ALA -21  ? A ALA 3   
4   1 Y 1 Q LEU -20  ? A LEU 4   
5   1 Y 1 Q SER -19  ? A SER 5   
6   1 Y 1 Q TYR -18  ? A TYR 6   
7   1 Y 1 Q ILE -17  ? A ILE 7   
8   1 Y 1 Q PHE -16  ? A PHE 8   
9   1 Y 1 Q CYS -15  ? A CYS 9   
10  1 Y 1 Q LEU -14  ? A LEU 10  
11  1 Y 1 Q VAL -13  ? A VAL 11  
12  1 Y 1 Q PHE -12  ? A PHE 12  
13  1 Y 1 Q ALA -11  ? A ALA 13  
14  1 Y 1 Q ASP -10  ? A ASP 14  
15  1 Y 1 Q TYR -9   ? A TYR 15  
16  1 Y 1 Q LYS -8   ? A LYS 16  
17  1 Y 1 Q ASP -7   ? A ASP 17  
18  1 Y 1 Q ASP -6   ? A ASP 18  
19  1 Y 1 Q ASP -5   ? A ASP 19  
20  1 Y 1 Q ASP -4   ? A ASP 20  
21  1 Y 1 Q ALA -3   ? A ALA 21  
22  1 Y 1 Q GLY -2   ? A GLY 22  
23  1 Y 1 Q ARG -1   ? A ARG 23  
24  1 Y 1 Q ALA 0    ? A ALA 24  
25  1 Y 1 Q MET 1    ? A MET 25  
26  1 Y 1 Q MET 2    ? A MET 26  
27  1 Y 1 Q TRP 3    ? A TRP 27  
28  1 Y 1 Q GLY 4    ? A GLY 28  
29  1 Y 1 Q ALA 5    ? A ALA 29  
30  1 Y 1 Q GLY 6    ? A GLY 30  
31  1 Y 1 Q SER 7    ? A SER 31  
32  1 Y 1 Q PRO 8    ? A PRO 32  
33  1 Y 1 Q LEU 9    ? A LEU 33  
34  1 Y 1 Q ALA 10   ? A ALA 34  
35  1 Y 1 Q TRP 11   ? A TRP 35  
36  1 Y 1 Q LEU 12   ? A LEU 36  
37  1 Y 1 Q SER 13   ? A SER 37  
38  1 Y 1 Q ALA 14   ? A ALA 38  
39  1 Y 1 Q GLY 15   ? A GLY 39  
40  1 Y 1 Q SER 16   ? A SER 40  
41  1 Y 1 Q GLY 17   ? A GLY 41  
42  1 Y 1 Q ASN 18   ? A ASN 42  
43  1 Y 1 Q VAL 19   ? A VAL 43  
44  1 Y 1 Q ASN 20   ? A ASN 44  
45  1 Y 1 Q VAL 21   ? A VAL 45  
46  1 Y 1 Q SER 22   ? A SER 46  
47  1 Y 1 Q SER 23   ? A SER 47  
48  1 Y 1 Q VAL 24   ? A VAL 48  
49  1 Y 1 Q GLY 25   ? A GLY 49  
50  1 Y 1 Q PRO 26   ? A PRO 50  
51  1 Y 1 Q ALA 27   ? A ALA 51  
52  1 Y 1 Q GLU 28   ? A GLU 52  
53  1 Y 1 Q GLY 29   ? A GLY 53  
54  1 Y 1 Q PRO 30   ? A PRO 54  
55  1 Y 1 Q THR 31   ? A THR 55  
56  1 Y 1 Q GLY 32   ? A GLY 56  
57  1 Y 1 Q PRO 33   ? A PRO 57  
58  1 Y 1 Q ALA 34   ? A ALA 58  
59  1 Y 1 Q GLN 225  ? A GLN 249 
60  1 Y 1 Q GLN 226  ? A GLN 250 
61  1 Y 1 Q ILE 227  ? A ILE 251 
62  1 Y 1 Q ALA 228  ? A ALA 252 
63  1 Y 1 Q LEU 229  ? A LEU 253 
64  1 Y 1 Q GLN 230  ? A GLN 254 
65  1 Y 1 Q ARG 231  ? A ARG 255 
66  1 Y 1 Q HIS 232  ? A HIS 256 
67  1 Y 1 Q LEU 233  ? A LEU 257 
68  1 Y 1 Q LEU 234  ? A LEU 258 
69  1 Y 1 Q PRO 235  ? A PRO 259 
70  1 Y 1 Q ALA 236  ? A ALA 260 
71  1 Y 1 Q SER 237  ? A SER 261 
72  1 Y 1 Q HIS 238  ? A HIS 262 
73  1 Y 1 Q TYR 239  ? A TYR 263 
74  1 Y 1 Q VAL 240  ? A VAL 264 
75  1 Y 1 Q CYS 963  ? A CYS 337 
76  1 Y 1 Q CYS 964  ? A CYS 338 
77  1 Y 1 Q CYS 965  ? A CYS 339 
78  1 Y 1 Q SER 966  ? A SER 340 
79  1 Y 1 Q SER 967  ? A SER 341 
80  1 Y 1 Q SER 968  ? A SER 342 
81  1 Y 1 Q LYS 969  ? A LYS 343 
82  1 Y 1 Q ILE 970  ? A ILE 344 
83  1 Y 1 Q PRO 971  ? A PRO 345 
84  1 Y 1 Q PHE 972  ? A PHE 346 
85  1 Y 1 Q ARG 973  ? A ARG 347 
86  1 Y 1 Q SER 974  ? A SER 348 
87  1 Y 1 Q ARG 975  ? A ARG 349 
88  1 Y 1 Q SER 976  ? A SER 350 
89  1 Y 1 Q PRO 977  ? A PRO 351 
90  1 Y 1 Q SER 978  ? A SER 352 
91  1 Y 1 Q ASP 979  ? A ASP 353 
92  1 Y 1 Q VAL 980  ? A VAL 354 
93  1 Y 1 Q GLU 981  ? A GLU 355 
94  1 Y 1 Q PHE 982  ? A PHE 356 
95  1 Y 1 Q LEU 983  ? A LEU 357 
96  1 Y 1 Q GLU 984  ? A GLU 358 
97  1 Y 1 Q VAL 985  ? A VAL 359 
98  1 Y 1 Q LEU 986  ? A LEU 360 
99  1 Y 1 Q PHE 987  ? A PHE 361 
100 1 Y 1 Q GLN 988  ? A GLN 362 
101 1 Y 1 Q GLY 989  ? A GLY 363 
102 1 Y 1 Q PRO 990  ? A PRO 364 
103 1 Y 1 Q HIS 991  ? A HIS 365 
104 1 Y 1 Q HIS 992  ? A HIS 366 
105 1 Y 1 Q HIS 993  ? A HIS 367 
106 1 Y 1 Q HIS 994  ? A HIS 368 
107 1 Y 1 Q HIS 995  ? A HIS 369 
108 1 Y 1 Q HIS 996  ? A HIS 370 
109 1 Y 1 Q HIS 997  ? A HIS 371 
110 1 Y 1 Q HIS 998  ? A HIS 372 
111 1 Y 1 Q HIS 999  ? A HIS 373 
112 1 Y 1 Q HIS 1000 ? A HIS 374 
113 1 Y 1 R ILE -23  ? B ILE 1   
114 1 Y 1 R ILE -22  ? B ILE 2   
115 1 Y 1 R ALA -21  ? B ALA 3   
116 1 Y 1 R LEU -20  ? B LEU 4   
117 1 Y 1 R SER -19  ? B SER 5   
118 1 Y 1 R TYR -18  ? B TYR 6   
119 1 Y 1 R ILE -17  ? B ILE 7   
120 1 Y 1 R PHE -16  ? B PHE 8   
121 1 Y 1 R CYS -15  ? B CYS 9   
122 1 Y 1 R LEU -14  ? B LEU 10  
123 1 Y 1 R VAL -13  ? B VAL 11  
124 1 Y 1 R PHE -12  ? B PHE 12  
125 1 Y 1 R ALA -11  ? B ALA 13  
126 1 Y 1 R ASP -10  ? B ASP 14  
127 1 Y 1 R TYR -9   ? B TYR 15  
128 1 Y 1 R LYS -8   ? B LYS 16  
129 1 Y 1 R ASP -7   ? B ASP 17  
130 1 Y 1 R ASP -6   ? B ASP 18  
131 1 Y 1 R ASP -5   ? B ASP 19  
132 1 Y 1 R ASP -4   ? B ASP 20  
133 1 Y 1 R ALA -3   ? B ALA 21  
134 1 Y 1 R GLY -2   ? B GLY 22  
135 1 Y 1 R ARG -1   ? B ARG 23  
136 1 Y 1 R ALA 0    ? B ALA 24  
137 1 Y 1 R MET 1    ? B MET 25  
138 1 Y 1 R MET 2    ? B MET 26  
139 1 Y 1 R TRP 3    ? B TRP 27  
140 1 Y 1 R GLY 4    ? B GLY 28  
141 1 Y 1 R ALA 5    ? B ALA 29  
142 1 Y 1 R GLY 6    ? B GLY 30  
143 1 Y 1 R SER 7    ? B SER 31  
144 1 Y 1 R PRO 8    ? B PRO 32  
145 1 Y 1 R LEU 9    ? B LEU 33  
146 1 Y 1 R ALA 10   ? B ALA 34  
147 1 Y 1 R TRP 11   ? B TRP 35  
148 1 Y 1 R LEU 12   ? B LEU 36  
149 1 Y 1 R SER 13   ? B SER 37  
150 1 Y 1 R ALA 14   ? B ALA 38  
151 1 Y 1 R GLY 15   ? B GLY 39  
152 1 Y 1 R SER 16   ? B SER 40  
153 1 Y 1 R GLY 17   ? B GLY 41  
154 1 Y 1 R ASN 18   ? B ASN 42  
155 1 Y 1 R VAL 19   ? B VAL 43  
156 1 Y 1 R ASN 20   ? B ASN 44  
157 1 Y 1 R VAL 21   ? B VAL 45  
158 1 Y 1 R SER 22   ? B SER 46  
159 1 Y 1 R SER 23   ? B SER 47  
160 1 Y 1 R VAL 24   ? B VAL 48  
161 1 Y 1 R GLY 25   ? B GLY 49  
162 1 Y 1 R PRO 26   ? B PRO 50  
163 1 Y 1 R ALA 27   ? B ALA 51  
164 1 Y 1 R GLU 28   ? B GLU 52  
165 1 Y 1 R GLY 29   ? B GLY 53  
166 1 Y 1 R PRO 30   ? B PRO 54  
167 1 Y 1 R THR 31   ? B THR 55  
168 1 Y 1 R GLY 32   ? B GLY 56  
169 1 Y 1 R PRO 33   ? B PRO 57  
170 1 Y 1 R ALA 34   ? B ALA 58  
171 1 Y 1 R GLN 225  ? B GLN 249 
172 1 Y 1 R GLN 226  ? B GLN 250 
173 1 Y 1 R ILE 227  ? B ILE 251 
174 1 Y 1 R ALA 228  ? B ALA 252 
175 1 Y 1 R LEU 229  ? B LEU 253 
176 1 Y 1 R GLN 230  ? B GLN 254 
177 1 Y 1 R ARG 231  ? B ARG 255 
178 1 Y 1 R HIS 232  ? B HIS 256 
179 1 Y 1 R LEU 233  ? B LEU 257 
180 1 Y 1 R LEU 234  ? B LEU 258 
181 1 Y 1 R PRO 235  ? B PRO 259 
182 1 Y 1 R ALA 236  ? B ALA 260 
183 1 Y 1 R SER 237  ? B SER 261 
184 1 Y 1 R HIS 238  ? B HIS 262 
185 1 Y 1 R TYR 239  ? B TYR 263 
186 1 Y 1 R VAL 240  ? B VAL 264 
187 1 Y 1 R CYS 963  ? B CYS 337 
188 1 Y 1 R CYS 964  ? B CYS 338 
189 1 Y 1 R CYS 965  ? B CYS 339 
190 1 Y 1 R SER 966  ? B SER 340 
191 1 Y 1 R SER 967  ? B SER 341 
192 1 Y 1 R SER 968  ? B SER 342 
193 1 Y 1 R LYS 969  ? B LYS 343 
194 1 Y 1 R ILE 970  ? B ILE 344 
195 1 Y 1 R PRO 971  ? B PRO 345 
196 1 Y 1 R PHE 972  ? B PHE 346 
197 1 Y 1 R ARG 973  ? B ARG 347 
198 1 Y 1 R SER 974  ? B SER 348 
199 1 Y 1 R ARG 975  ? B ARG 349 
200 1 Y 1 R SER 976  ? B SER 350 
201 1 Y 1 R PRO 977  ? B PRO 351 
202 1 Y 1 R SER 978  ? B SER 352 
203 1 Y 1 R ASP 979  ? B ASP 353 
204 1 Y 1 R VAL 980  ? B VAL 354 
205 1 Y 1 R GLU 981  ? B GLU 355 
206 1 Y 1 R PHE 982  ? B PHE 356 
207 1 Y 1 R LEU 983  ? B LEU 357 
208 1 Y 1 R GLU 984  ? B GLU 358 
209 1 Y 1 R VAL 985  ? B VAL 359 
210 1 Y 1 R LEU 986  ? B LEU 360 
211 1 Y 1 R PHE 987  ? B PHE 361 
212 1 Y 1 R GLN 988  ? B GLN 362 
213 1 Y 1 R GLY 989  ? B GLY 363 
214 1 Y 1 R PRO 990  ? B PRO 364 
215 1 Y 1 R HIS 991  ? B HIS 365 
216 1 Y 1 R HIS 992  ? B HIS 366 
217 1 Y 1 R HIS 993  ? B HIS 367 
218 1 Y 1 R HIS 994  ? B HIS 368 
219 1 Y 1 R HIS 995  ? B HIS 369 
220 1 Y 1 R HIS 996  ? B HIS 370 
221 1 Y 1 R HIS 997  ? B HIS 371 
222 1 Y 1 R HIS 998  ? B HIS 372 
223 1 Y 1 R HIS 999  ? B HIS 373 
224 1 Y 1 R HIS 1000 ? B HIS 374 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    YES 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.21 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          7108 
_em_entity_assembly_recombinant.organism             'Spodoptera frugiperda' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         60 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'FEI FALCON IV (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ? ? 
MASKING                         ? 3  ? ? ? ? ? 
'CTF CORRECTION'                ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ? ? 
'MODEL FITTING'                 ? 7  ? 1 ? ? ? 
OTHER                           ? 8  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT'      ? 9  1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'        ? 10 1 ? ? ? ? 
CLASSIFICATION                  ? 11 1 ? ? ? ? 
RECONSTRUCTION                  ? 12 1 ? ? ? ? 
'MODEL REFINEMENT'              ? 13 ? 1 ? ? ? 
'VOLUME SELECTION'              ? 14 1 1 1 ? ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ? ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ? ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ? ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ? ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Science Foundation (NSF, China)'            China 32022038 1 
'National Natural Science Foundation of China (NSFC)' China 32230026 2 
# 
_atom_sites.entry_id                    9LYD 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . ALA A 1 59  ? 135.221 153.424 160.722 1.00 120.67 ?  35   ALA Q N   1 
ATOM 2    C CA  . ALA A 1 59  ? 134.998 152.277 159.851 1.00 120.67 ?  35   ALA Q CA  1 
ATOM 3    C C   . ALA A 1 59  ? 135.981 152.281 158.686 1.00 120.67 ?  35   ALA Q C   1 
ATOM 4    O O   . ALA A 1 59  ? 135.662 152.765 157.600 1.00 120.67 ?  35   ALA Q O   1 
ATOM 5    C CB  . ALA A 1 59  ? 133.567 152.271 159.338 1.00 120.67 ?  35   ALA Q CB  1 
ATOM 6    N N   . PRO A 1 60  ? 137.175 151.741 158.910 1.00 120.58 ?  36   PRO Q N   1 
ATOM 7    C CA  . PRO A 1 60  ? 138.183 151.713 157.848 1.00 120.58 ?  36   PRO Q CA  1 
ATOM 8    C C   . PRO A 1 60  ? 138.000 150.521 156.923 1.00 120.58 ?  36   PRO Q C   1 
ATOM 9    O O   . PRO A 1 60  ? 137.567 149.441 157.329 1.00 120.58 ?  36   PRO Q O   1 
ATOM 10   C CB  . PRO A 1 60  ? 139.502 151.613 158.621 1.00 120.58 ?  36   PRO Q CB  1 
ATOM 11   C CG  . PRO A 1 60  ? 139.138 150.953 159.923 1.00 120.58 ?  36   PRO Q CG  1 
ATOM 12   C CD  . PRO A 1 60  ? 137.651 151.100 160.147 1.00 120.58 ?  36   PRO Q CD  1 
ATOM 13   N N   . LEU A 1 61  ? 138.340 150.735 155.658 1.00 115.76 ?  37   LEU Q N   1 
ATOM 14   C CA  . LEU A 1 61  ? 138.238 149.675 154.665 1.00 115.76 ?  37   LEU Q CA  1 
ATOM 15   C C   . LEU A 1 61  ? 139.385 148.689 154.843 1.00 115.76 ?  37   LEU Q C   1 
ATOM 16   O O   . LEU A 1 61  ? 140.550 149.103 154.840 1.00 115.76 ?  37   LEU Q O   1 
ATOM 17   C CB  . LEU A 1 61  ? 138.257 150.254 153.258 1.00 115.76 ?  37   LEU Q CB  1 
ATOM 18   C CG  . LEU A 1 61  ? 136.897 150.641 152.674 1.00 115.76 ?  37   LEU Q CG  1 
ATOM 19   C CD1 . LEU A 1 61  ? 137.031 150.990 151.202 1.00 115.76 ?  37   LEU Q CD1 1 
ATOM 20   C CD2 . LEU A 1 61  ? 135.885 149.523 152.874 1.00 115.76 ?  37   LEU Q CD2 1 
ATOM 21   N N   . PRO A 1 62  ? 139.109 147.396 155.011 1.00 106.84 ?  38   PRO Q N   1 
ATOM 22   C CA  . PRO A 1 62  ? 140.196 146.424 155.171 1.00 106.84 ?  38   PRO Q CA  1 
ATOM 23   C C   . PRO A 1 62  ? 141.090 146.384 153.942 1.00 106.84 ?  38   PRO Q C   1 
ATOM 24   O O   . PRO A 1 62  ? 140.642 146.583 152.812 1.00 106.84 ?  38   PRO Q O   1 
ATOM 25   C CB  . PRO A 1 62  ? 139.468 145.089 155.371 1.00 106.84 ?  38   PRO Q CB  1 
ATOM 26   C CG  . PRO A 1 62  ? 138.035 145.339 155.052 1.00 106.84 ?  38   PRO Q CG  1 
ATOM 27   C CD  . PRO A 1 62  ? 137.775 146.798 155.172 1.00 106.84 ?  38   PRO Q CD  1 
ATOM 28   N N   . SER A 1 63  ? 142.367 146.125 154.177 1.00 107.52 ?  39   SER Q N   1 
ATOM 29   C CA  . SER A 1 63  ? 143.334 146.066 153.090 1.00 107.52 ?  39   SER Q CA  1 
ATOM 30   C C   . SER A 1 63  ? 143.088 144.820 152.251 1.00 107.52 ?  39   SER Q C   1 
ATOM 31   O O   . SER A 1 63  ? 143.130 143.705 152.787 1.00 107.52 ?  39   SER Q O   1 
ATOM 32   C CB  . SER A 1 63  ? 144.754 146.065 153.645 1.00 107.52 ?  39   SER Q CB  1 
ATOM 33   O OG  . SER A 1 63  ? 144.910 147.066 154.635 1.00 107.52 ?  39   SER Q OG  1 
ATOM 34   N N   . PRO A 1 64  ? 142.824 144.952 150.954 1.00 110.63 ?  40   PRO Q N   1 
ATOM 35   C CA  . PRO A 1 64  ? 142.528 143.771 150.138 1.00 110.63 ?  40   PRO Q CA  1 
ATOM 36   C C   . PRO A 1 64  ? 143.734 142.860 149.983 1.00 110.63 ?  40   PRO Q C   1 
ATOM 37   O O   . PRO A 1 64  ? 144.887 143.298 150.003 1.00 110.63 ?  40   PRO Q O   1 
ATOM 38   C CB  . PRO A 1 64  ? 142.109 144.369 148.789 1.00 110.63 ?  40   PRO Q CB  1 
ATOM 39   C CG  . PRO A 1 64  ? 141.702 145.778 149.105 1.00 110.63 ?  40   PRO Q CG  1 
ATOM 40   C CD  . PRO A 1 64  ? 142.613 146.203 150.211 1.00 110.63 ?  40   PRO Q CD  1 
ATOM 41   N N   . LYS A 1 65  ? 143.448 141.570 149.824 1.00 109.84 ?  41   LYS Q N   1 
ATOM 42   C CA  . LYS A 1 65  ? 144.470 140.565 149.591 1.00 109.84 ?  41   LYS Q CA  1 
ATOM 43   C C   . LYS A 1 65  ? 144.937 140.678 148.135 1.00 109.84 ?  41   LYS Q C   1 
ATOM 44   O O   . LYS A 1 65  ? 144.329 141.375 147.318 1.00 109.84 ?  41   LYS Q O   1 
ATOM 45   C CB  . LYS A 1 65  ? 143.898 139.177 149.920 1.00 109.84 ?  41   LYS Q CB  1 
ATOM 46   C CG  . LYS A 1 65  ? 144.778 137.886 149.870 1.00 109.84 ?  41   LYS Q CG  1 
ATOM 47   C CD  . LYS A 1 65  ? 146.315 138.004 149.912 1.00 109.84 ?  41   LYS Q CD  1 
ATOM 48   C CE  . LYS A 1 65  ? 146.849 138.821 151.089 1.00 109.84 ?  41   LYS Q CE  1 
ATOM 49   N NZ  . LYS A 1 65  ? 148.326 138.995 151.013 1.00 109.84 1  41   LYS Q NZ  1 
ATOM 50   N N   . ALA A 1 66  ? 146.033 139.988 147.810 1.00 114.17 ?  42   ALA Q N   1 
ATOM 51   C CA  . ALA A 1 66  ? 146.681 140.162 146.512 1.00 114.17 ?  42   ALA Q CA  1 
ATOM 52   C C   . ALA A 1 66  ? 145.750 139.819 145.355 1.00 114.17 ?  42   ALA Q C   1 
ATOM 53   O O   . ALA A 1 66  ? 145.801 140.464 144.302 1.00 114.17 ?  42   ALA Q O   1 
ATOM 54   C CB  . ALA A 1 66  ? 147.949 139.312 146.445 1.00 114.17 ?  42   ALA Q CB  1 
ATOM 55   N N   . TRP A 1 67  ? 144.887 138.815 145.526 1.00 112.56 ?  43   TRP Q N   1 
ATOM 56   C CA  . TRP A 1 67  ? 144.005 138.427 144.431 1.00 112.56 ?  43   TRP Q CA  1 
ATOM 57   C C   . TRP A 1 67  ? 143.192 139.609 143.921 1.00 112.56 ?  43   TRP Q C   1 
ATOM 58   O O   . TRP A 1 67  ? 142.886 139.688 142.723 1.00 112.56 ?  43   TRP Q O   1 
ATOM 59   C CB  . TRP A 1 67  ? 143.078 137.298 144.877 1.00 112.56 ?  43   TRP Q CB  1 
ATOM 60   C CG  . TRP A 1 67  ? 143.781 136.157 145.537 1.00 112.56 ?  43   TRP Q CG  1 
ATOM 61   C CD1 . TRP A 1 67  ? 143.758 135.837 146.860 1.00 112.56 ?  43   TRP Q CD1 1 
ATOM 62   C CD2 . TRP A 1 67  ? 144.607 135.176 144.900 1.00 112.56 ?  43   TRP Q CD2 1 
ATOM 63   N NE1 . TRP A 1 67  ? 144.521 134.719 147.090 1.00 112.56 ?  43   TRP Q NE1 1 
ATOM 64   C CE2 . TRP A 1 67  ? 145.053 134.294 145.902 1.00 112.56 ?  43   TRP Q CE2 1 
ATOM 65   C CE3 . TRP A 1 67  ? 145.013 134.959 143.581 1.00 112.56 ?  43   TRP Q CE3 1 
ATOM 66   C CZ2 . TRP A 1 67  ? 145.887 133.213 145.627 1.00 112.56 ?  43   TRP Q CZ2 1 
ATOM 67   C CZ3 . TRP A 1 67  ? 145.841 133.885 143.309 1.00 112.56 ?  43   TRP Q CZ3 1 
ATOM 68   C CH2 . TRP A 1 67  ? 146.268 133.025 144.328 1.00 112.56 ?  43   TRP Q CH2 1 
ATOM 69   N N   . ASP A 1 68  ? 142.859 140.550 144.806 1.00 115.57 ?  44   ASP Q N   1 
ATOM 70   C CA  . ASP A 1 68  ? 142.142 141.743 144.376 1.00 115.57 ?  44   ASP Q CA  1 
ATOM 71   C C   . ASP A 1 68  ? 142.966 142.560 143.389 1.00 115.57 ?  44   ASP Q C   1 
ATOM 72   O O   . ASP A 1 68  ? 142.449 143.002 142.354 1.00 115.57 ?  44   ASP Q O   1 
ATOM 73   C CB  . ASP A 1 68  ? 141.759 142.590 145.588 1.00 115.57 ?  44   ASP Q CB  1 
ATOM 74   C CG  . ASP A 1 68  ? 140.470 143.360 145.377 1.00 115.57 ?  44   ASP Q CG  1 
ATOM 75   O OD1 . ASP A 1 68  ? 139.960 143.365 144.237 1.00 115.57 ?  44   ASP Q OD1 1 
ATOM 76   O OD2 . ASP A 1 68  ? 139.966 143.957 146.351 1.00 115.57 -1 44   ASP Q OD2 1 
ATOM 77   N N   . VAL A 1 69  ? 144.255 142.765 143.675 1.00 117.14 ?  45   VAL Q N   1 
ATOM 78   C CA  . VAL A 1 69  ? 145.044 143.564 142.745 1.00 117.14 ?  45   VAL Q CA  1 
ATOM 79   C C   . VAL A 1 69  ? 145.314 142.773 141.470 1.00 117.14 ?  45   VAL Q C   1 
ATOM 80   O O   . VAL A 1 69  ? 145.439 143.361 140.392 1.00 117.14 ?  45   VAL Q O   1 
ATOM 81   C CB  . VAL A 1 69  ? 146.347 144.088 143.391 1.00 117.14 ?  45   VAL Q CB  1 
ATOM 82   C CG1 . VAL A 1 69  ? 147.257 142.965 143.838 1.00 117.14 ?  45   VAL Q CG1 1 
ATOM 83   C CG2 . VAL A 1 69  ? 147.079 145.035 142.446 1.00 117.14 ?  45   VAL Q CG2 1 
ATOM 84   N N   . VAL A 1 70  ? 145.380 141.440 141.550 1.00 114.00 ?  46   VAL Q N   1 
ATOM 85   C CA  . VAL A 1 70  ? 145.498 140.659 140.317 1.00 114.00 ?  46   VAL Q CA  1 
ATOM 86   C C   . VAL A 1 70  ? 144.279 140.877 139.431 1.00 114.00 ?  46   VAL Q C   1 
ATOM 87   O O   . VAL A 1 70  ? 144.402 141.080 138.215 1.00 114.00 ?  46   VAL Q O   1 
ATOM 88   C CB  . VAL A 1 70  ? 145.713 139.164 140.619 1.00 114.00 ?  46   VAL Q CB  1 
ATOM 89   C CG1 . VAL A 1 70  ? 146.335 138.480 139.414 1.00 114.00 ?  46   VAL Q CG1 1 
ATOM 90   C CG2 . VAL A 1 70  ? 146.622 138.987 141.809 1.00 114.00 ?  46   VAL Q CG2 1 
ATOM 91   N N   . LEU A 1 71  ? 143.085 140.839 140.025 1.00 113.63 ?  47   LEU Q N   1 
ATOM 92   C CA  . LEU A 1 71  ? 141.875 141.119 139.257 1.00 113.63 ?  47   LEU Q CA  1 
ATOM 93   C C   . LEU A 1 71  ? 141.904 142.532 138.687 1.00 113.63 ?  47   LEU Q C   1 
ATOM 94   O O   . LEU A 1 71  ? 141.481 142.761 137.546 1.00 113.63 ?  47   LEU Q O   1 
ATOM 95   C CB  . LEU A 1 71  ? 140.640 140.917 140.133 1.00 113.63 ?  47   LEU Q CB  1 
ATOM 96   C CG  . LEU A 1 71  ? 140.039 139.512 140.160 1.00 113.63 ?  47   LEU Q CG  1 
ATOM 97   C CD1 . LEU A 1 71  ? 138.586 139.564 140.598 1.00 113.63 ?  47   LEU Q CD1 1 
ATOM 98   C CD2 . LEU A 1 71  ? 140.156 138.861 138.795 1.00 113.63 ?  47   LEU Q CD2 1 
ATOM 99   N N   . CYS A 1 72  ? 142.399 143.491 139.471 1.00 117.50 ?  48   CYS Q N   1 
ATOM 100  C CA  . CYS A 1 72  ? 142.483 144.867 138.994 1.00 117.50 ?  48   CYS Q CA  1 
ATOM 101  C C   . CYS A 1 72  ? 143.389 144.979 137.773 1.00 117.50 ?  48   CYS Q C   1 
ATOM 102  O O   . CYS A 1 72  ? 143.036 145.639 136.789 1.00 117.50 ?  48   CYS Q O   1 
ATOM 103  C CB  . CYS A 1 72  ? 142.983 145.778 140.113 1.00 117.50 ?  48   CYS Q CB  1 
ATOM 104  S SG  . CYS A 1 72  ? 143.758 147.304 139.534 1.00 117.50 ?  48   CYS Q SG  1 
ATOM 105  N N   . ILE A 1 73  ? 144.561 144.341 137.818 1.00 113.36 ?  49   ILE Q N   1 
ATOM 106  C CA  . ILE A 1 73  ? 145.473 144.379 136.674 1.00 113.36 ?  49   ILE Q CA  1 
ATOM 107  C C   . ILE A 1 73  ? 144.843 143.702 135.465 1.00 113.36 ?  49   ILE Q C   1 
ATOM 108  O O   . ILE A 1 73  ? 144.951 144.193 134.331 1.00 113.36 ?  49   ILE Q O   1 
ATOM 109  C CB  . ILE A 1 73  ? 146.838 143.751 137.028 1.00 113.36 ?  49   ILE Q CB  1 
ATOM 110  C CG1 . ILE A 1 73  ? 147.389 144.268 138.362 1.00 113.36 ?  49   ILE Q CG1 1 
ATOM 111  C CG2 . ILE A 1 73  ? 147.851 144.010 135.934 1.00 113.36 ?  49   ILE Q CG2 1 
ATOM 112  C CD1 . ILE A 1 73  ? 147.198 145.758 138.599 1.00 113.36 ?  49   ILE Q CD1 1 
ATOM 113  N N   . SER A 1 74  ? 144.184 142.561 135.679 1.00 111.24 ?  50   SER Q N   1 
ATOM 114  C CA  . SER A 1 74  ? 143.549 141.872 134.563 1.00 111.24 ?  50   SER Q CA  1 
ATOM 115  C C   . SER A 1 74  ? 142.518 142.770 133.891 1.00 111.24 ?  50   SER Q C   1 
ATOM 116  O O   . SER A 1 74  ? 142.499 142.905 132.660 1.00 111.24 ?  50   SER Q O   1 
ATOM 117  C CB  . SER A 1 74  ? 142.906 140.572 135.046 1.00 111.24 ?  50   SER Q CB  1 
ATOM 118  O OG  . SER A 1 74  ? 142.302 139.876 133.969 1.00 111.24 ?  50   SER Q OG  1 
ATOM 119  N N   . GLY A 1 75  ? 141.676 143.424 134.691 1.00 109.36 ?  51   GLY Q N   1 
ATOM 120  C CA  . GLY A 1 75  ? 140.690 144.329 134.123 1.00 109.36 ?  51   GLY Q CA  1 
ATOM 121  C C   . GLY A 1 75  ? 141.322 145.518 133.425 1.00 109.36 ?  51   GLY Q C   1 
ATOM 122  O O   . GLY A 1 75  ? 140.835 145.973 132.385 1.00 109.36 ?  51   GLY Q O   1 
ATOM 123  N N   . THR A 1 76  ? 142.413 146.040 133.989 1.00 113.54 ?  52   THR Q N   1 
ATOM 124  C CA  . THR A 1 76  ? 143.067 147.201 133.398 1.00 113.54 ?  52   THR Q CA  1 
ATOM 125  C C   . THR A 1 76  ? 143.603 146.879 132.010 1.00 113.54 ?  52   THR Q C   1 
ATOM 126  O O   . THR A 1 76  ? 143.361 147.621 131.050 1.00 113.54 ?  52   THR Q O   1 
ATOM 127  C CB  . THR A 1 76  ? 144.193 147.687 134.309 1.00 113.54 ?  52   THR Q CB  1 
ATOM 128  O OG1 . THR A 1 76  ? 143.784 147.575 135.678 1.00 113.54 ?  52   THR Q OG1 1 
ATOM 129  C CG2 . THR A 1 76  ? 144.534 149.139 134.004 1.00 113.54 ?  52   THR Q CG2 1 
ATOM 130  N N   . LEU A 1 77  ? 144.326 145.765 131.880 1.00 110.50 ?  53   LEU Q N   1 
ATOM 131  C CA  . LEU A 1 77  ? 144.802 145.384 130.553 1.00 110.50 ?  53   LEU Q CA  1 
ATOM 132  C C   . LEU A 1 77  ? 143.665 144.976 129.625 1.00 110.50 ?  53   LEU Q C   1 
ATOM 133  O O   . LEU A 1 77  ? 143.774 145.177 128.413 1.00 110.50 ?  53   LEU Q O   1 
ATOM 134  C CB  . LEU A 1 77  ? 145.864 144.284 130.621 1.00 110.50 ?  53   LEU Q CB  1 
ATOM 135  C CG  . LEU A 1 77  ? 147.258 144.555 131.211 1.00 110.50 ?  53   LEU Q CG  1 
ATOM 136  C CD1 . LEU A 1 77  ? 147.991 145.549 130.319 1.00 110.50 ?  53   LEU Q CD1 1 
ATOM 137  C CD2 . LEU A 1 77  ? 147.270 145.061 132.628 1.00 110.50 ?  53   LEU Q CD2 1 
ATOM 138  N N   . VAL A 1 78  ? 142.567 144.430 130.152 1.00 107.72 ?  54   VAL Q N   1 
ATOM 139  C CA  . VAL A 1 78  ? 141.428 144.119 129.289 1.00 107.72 ?  54   VAL Q CA  1 
ATOM 140  C C   . VAL A 1 78  ? 140.876 145.396 128.663 1.00 107.72 ?  54   VAL Q C   1 
ATOM 141  O O   . VAL A 1 78  ? 140.661 145.478 127.444 1.00 107.72 ?  54   VAL Q O   1 
ATOM 142  C CB  . VAL A 1 78  ? 140.347 143.363 130.081 1.00 107.72 ?  54   VAL Q CB  1 
ATOM 143  C CG1 . VAL A 1 78  ? 138.967 143.624 129.493 1.00 107.72 ?  54   VAL Q CG1 1 
ATOM 144  C CG2 . VAL A 1 78  ? 140.649 141.875 130.106 1.00 107.72 ?  54   VAL Q CG2 1 
ATOM 145  N N   . SER A 1 79  ? 140.660 146.419 129.492 1.00 109.55 ?  55   SER Q N   1 
ATOM 146  C CA  . SER A 1 79  ? 140.153 147.689 128.984 1.00 109.55 ?  55   SER Q CA  1 
ATOM 147  C C   . SER A 1 79  ? 141.144 148.332 128.024 1.00 109.55 ?  55   SER Q C   1 
ATOM 148  O O   . SER A 1 79  ? 140.749 148.873 126.984 1.00 109.55 ?  55   SER Q O   1 
ATOM 149  C CB  . SER A 1 79  ? 139.843 148.633 130.145 1.00 109.55 ?  55   SER Q CB  1 
ATOM 150  O OG  . SER A 1 79  ? 138.784 148.133 130.941 1.00 109.55 ?  55   SER Q OG  1 
ATOM 151  N N   . CYS A 1 80  ? 142.436 148.288 128.359 1.00 119.18 ?  56   CYS Q N   1 
ATOM 152  C CA  . CYS A 1 80  ? 143.441 148.888 127.489 1.00 119.18 ?  56   CYS Q CA  1 
ATOM 153  C C   . CYS A 1 80  ? 143.483 148.192 126.136 1.00 119.18 ?  56   CYS Q C   1 
ATOM 154  O O   . CYS A 1 80  ? 143.602 148.848 125.094 1.00 119.18 ?  56   CYS Q O   1 
ATOM 155  C CB  . CYS A 1 80  ? 144.813 148.841 128.161 1.00 119.18 ?  56   CYS Q CB  1 
ATOM 156  S SG  . CYS A 1 80  ? 145.001 149.973 129.558 1.00 119.18 ?  56   CYS Q SG  1 
ATOM 157  N N   . GLU A 1 81  ? 143.388 146.861 126.130 1.00 113.14 ?  57   GLU Q N   1 
ATOM 158  C CA  . GLU A 1 81  ? 143.397 146.124 124.876 1.00 113.14 ?  57   GLU Q CA  1 
ATOM 159  C C   . GLU A 1 81  ? 142.169 146.448 124.038 1.00 113.14 ?  57   GLU Q C   1 
ATOM 160  O O   . GLU A 1 81  ? 142.278 146.641 122.821 1.00 113.14 ?  57   GLU Q O   1 
ATOM 161  C CB  . GLU A 1 81  ? 143.484 144.623 125.153 1.00 113.14 ?  57   GLU Q CB  1 
ATOM 162  C CG  . GLU A 1 81  ? 142.718 143.749 124.171 1.00 113.14 ?  57   GLU Q CG  1 
ATOM 163  C CD  . GLU A 1 81  ? 143.479 143.518 122.878 1.00 113.14 ?  57   GLU Q CD  1 
ATOM 164  O OE1 . GLU A 1 81  ? 144.655 143.930 122.796 1.00 113.14 ?  57   GLU Q OE1 1 
ATOM 165  O OE2 . GLU A 1 81  ? 142.900 142.923 121.945 1.00 113.14 -1 57   GLU Q OE2 1 
ATOM 166  N N   . ASN A 1 82  ? 140.992 146.524 124.661 1.00 107.60 ?  58   ASN Q N   1 
ATOM 167  C CA  . ASN A 1 82  ? 139.798 146.756 123.856 1.00 107.60 ?  58   ASN Q CA  1 
ATOM 168  C C   . ASN A 1 82  ? 139.603 148.207 123.442 1.00 107.60 ?  58   ASN Q C   1 
ATOM 169  O O   . ASN A 1 82  ? 138.846 148.460 122.497 1.00 107.60 ?  58   ASN Q O   1 
ATOM 170  C CB  . ASN A 1 82  ? 138.542 146.283 124.576 1.00 107.60 ?  58   ASN Q CB  1 
ATOM 171  C CG  . ASN A 1 82  ? 138.105 144.924 124.113 1.00 107.60 ?  58   ASN Q CG  1 
ATOM 172  O OD1 . ASN A 1 82  ? 138.920 144.116 123.682 1.00 107.60 ?  58   ASN Q OD1 1 
ATOM 173  N ND2 . ASN A 1 82  ? 136.804 144.691 124.121 1.00 107.60 ?  58   ASN Q ND2 1 
ATOM 174  N N   . ALA A 1 83  ? 140.238 149.162 124.122 1.00 112.65 ?  59   ALA Q N   1 
ATOM 175  C CA  . ALA A 1 83  ? 140.040 150.560 123.754 1.00 112.65 ?  59   ALA Q CA  1 
ATOM 176  C C   . ALA A 1 83  ? 140.454 150.804 122.309 1.00 112.65 ?  59   ALA Q C   1 
ATOM 177  O O   . ALA A 1 83  ? 139.713 151.417 121.528 1.00 112.65 ?  59   ALA Q O   1 
ATOM 178  C CB  . ALA A 1 83  ? 140.822 151.468 124.703 1.00 112.65 ?  59   ALA Q CB  1 
ATOM 179  N N   . LEU A 1 84  ? 141.627 150.301 121.926 1.00 111.60 ?  60   LEU Q N   1 
ATOM 180  C CA  . LEU A 1 84  ? 142.097 150.509 120.565 1.00 111.60 ?  60   LEU Q CA  1 
ATOM 181  C C   . LEU A 1 84  ? 141.174 149.842 119.555 1.00 111.60 ?  60   LEU Q C   1 
ATOM 182  O O   . LEU A 1 84  ? 140.867 150.427 118.510 1.00 111.60 ?  60   LEU Q O   1 
ATOM 183  C CB  . LEU A 1 84  ? 143.534 150.004 120.420 1.00 111.60 ?  60   LEU Q CB  1 
ATOM 184  C CG  . LEU A 1 84  ? 143.825 148.508 120.556 1.00 111.60 ?  60   LEU Q CG  1 
ATOM 185  C CD1 . LEU A 1 84  ? 144.048 147.889 119.187 1.00 111.60 ?  60   LEU Q CD1 1 
ATOM 186  C CD2 . LEU A 1 84  ? 145.024 148.270 121.461 1.00 111.60 ?  60   LEU Q CD2 1 
ATOM 187  N N   . VAL A 1 85  ? 140.703 148.628 119.850 1.00 108.89 ?  61   VAL Q N   1 
ATOM 188  C CA  . VAL A 1 85  ? 139.912 147.918 118.851 1.00 108.89 ?  61   VAL Q CA  1 
ATOM 189  C C   . VAL A 1 85  ? 138.563 148.599 118.656 1.00 108.89 ?  61   VAL Q C   1 
ATOM 190  O O   . VAL A 1 85  ? 138.094 148.739 117.521 1.00 108.89 ?  61   VAL Q O   1 
ATOM 191  C CB  . VAL A 1 85  ? 139.765 146.423 119.201 1.00 108.89 ?  61   VAL Q CB  1 
ATOM 192  C CG1 . VAL A 1 85  ? 138.964 146.212 120.463 1.00 108.89 ?  61   VAL Q CG1 1 
ATOM 193  C CG2 . VAL A 1 85  ? 139.133 145.670 118.039 1.00 108.89 ?  61   VAL Q CG2 1 
ATOM 194  N N   . VAL A 1 86  ? 137.933 149.072 119.736 1.00 107.58 ?  62   VAL Q N   1 
ATOM 195  C CA  . VAL A 1 86  ? 136.667 149.774 119.541 1.00 107.58 ?  62   VAL Q CA  1 
ATOM 196  C C   . VAL A 1 86  ? 136.912 151.085 118.808 1.00 107.58 ?  62   VAL Q C   1 
ATOM 197  O O   . VAL A 1 86  ? 136.113 151.493 117.954 1.00 107.58 ?  62   VAL Q O   1 
ATOM 198  C CB  . VAL A 1 86  ? 135.918 150.001 120.871 1.00 107.58 ?  62   VAL Q CB  1 
ATOM 199  C CG1 . VAL A 1 86  ? 136.825 150.549 121.941 1.00 107.58 ?  62   VAL Q CG1 1 
ATOM 200  C CG2 . VAL A 1 86  ? 134.714 150.914 120.668 1.00 107.58 ?  62   VAL Q CG2 1 
ATOM 201  N N   . ALA A 1 87  ? 138.033 151.751 119.103 1.00 110.71 ?  63   ALA Q N   1 
ATOM 202  C CA  . ALA A 1 87  ? 138.345 153.001 118.419 1.00 110.71 ?  63   ALA Q CA  1 
ATOM 203  C C   . ALA A 1 87  ? 138.444 152.796 116.912 1.00 110.71 ?  63   ALA Q C   1 
ATOM 204  O O   . ALA A 1 87  ? 137.787 153.499 116.135 1.00 110.71 ?  63   ALA Q O   1 
ATOM 205  C CB  . ALA A 1 87  ? 139.643 153.590 118.971 1.00 110.71 ?  63   ALA Q CB  1 
ATOM 206  N N   . ILE A 1 88  ? 139.251 151.826 116.477 1.00 110.79 ?  64   ILE Q N   1 
ATOM 207  C CA  . ILE A 1 88  ? 139.411 151.616 115.039 1.00 110.79 ?  64   ILE Q CA  1 
ATOM 208  C C   . ILE A 1 88  ? 138.124 151.093 114.414 1.00 110.79 ?  64   ILE Q C   1 
ATOM 209  O O   . ILE A 1 88  ? 137.797 151.439 113.273 1.00 110.79 ?  64   ILE Q O   1 
ATOM 210  C CB  . ILE A 1 88  ? 140.607 150.698 114.729 1.00 110.79 ?  64   ILE Q CB  1 
ATOM 211  C CG1 . ILE A 1 88  ? 141.703 150.863 115.775 1.00 110.79 ?  64   ILE Q CG1 1 
ATOM 212  C CG2 . ILE A 1 88  ? 141.150 150.985 113.337 1.00 110.79 ?  64   ILE Q CG2 1 
ATOM 213  C CD1 . ILE A 1 88  ? 142.928 150.026 115.521 1.00 110.79 ?  64   ILE Q CD1 1 
ATOM 214  N N   . ILE A 1 89  ? 137.375 150.250 115.131 1.00 113.90 ?  65   ILE Q N   1 
ATOM 215  C CA  . ILE A 1 89  ? 136.133 149.723 114.571 1.00 113.90 ?  65   ILE Q CA  1 
ATOM 216  C C   . ILE A 1 89  ? 135.147 150.852 114.305 1.00 113.90 ?  65   ILE Q C   1 
ATOM 217  O O   . ILE A 1 89  ? 134.502 150.898 113.251 1.00 113.90 ?  65   ILE Q O   1 
ATOM 218  C CB  . ILE A 1 89  ? 135.535 148.651 115.501 1.00 113.90 ?  65   ILE Q CB  1 
ATOM 219  C CG1 . ILE A 1 89  ? 136.277 147.324 115.332 1.00 113.90 ?  65   ILE Q CG1 1 
ATOM 220  C CG2 . ILE A 1 89  ? 134.051 148.464 115.222 1.00 113.90 ?  65   ILE Q CG2 1 
ATOM 221  C CD1 . ILE A 1 89  ? 136.142 146.720 113.951 1.00 113.90 ?  65   ILE Q CD1 1 
ATOM 222  N N   . VAL A 1 90  ? 135.020 151.788 115.247 1.00 113.44 ?  66   VAL Q N   1 
ATOM 223  C CA  . VAL A 1 90  ? 134.091 152.894 115.053 1.00 113.44 ?  66   VAL Q CA  1 
ATOM 224  C C   . VAL A 1 90  ? 134.662 153.974 114.144 1.00 113.44 ?  66   VAL Q C   1 
ATOM 225  O O   . VAL A 1 90  ? 133.902 154.796 113.620 1.00 113.44 ?  66   VAL Q O   1 
ATOM 226  C CB  . VAL A 1 90  ? 133.684 153.498 116.408 1.00 113.44 ?  66   VAL Q CB  1 
ATOM 227  C CG1 . VAL A 1 90  ? 134.745 154.468 116.907 1.00 113.44 ?  66   VAL Q CG1 1 
ATOM 228  C CG2 . VAL A 1 90  ? 132.324 154.179 116.308 1.00 113.44 ?  66   VAL Q CG2 1 
ATOM 229  N N   . GLY A 1 91  ? 135.975 153.986 113.926 1.00 116.96 ?  67   GLY Q N   1 
ATOM 230  C CA  . GLY A 1 91  ? 136.608 155.074 113.205 1.00 116.96 ?  67   GLY Q CA  1 
ATOM 231  C C   . GLY A 1 91  ? 136.406 155.101 111.703 1.00 116.96 ?  67   GLY Q C   1 
ATOM 232  O O   . GLY A 1 91  ? 135.757 156.012 111.182 1.00 116.96 ?  67   GLY Q O   1 
ATOM 233  N N   . THR A 1 92  ? 136.948 154.115 111.001 1.00 117.81 ?  68   THR Q N   1 
ATOM 234  C CA  . THR A 1 92  ? 137.014 154.167 109.541 1.00 117.81 ?  68   THR Q CA  1 
ATOM 235  C C   . THR A 1 92  ? 135.626 154.038 108.926 1.00 117.81 ?  68   THR Q C   1 
ATOM 236  O O   . THR A 1 92  ? 134.933 153.046 109.186 1.00 117.81 ?  68   THR Q O   1 
ATOM 237  C CB  . THR A 1 92  ? 137.926 153.064 109.013 1.00 117.81 ?  68   THR Q CB  1 
ATOM 238  O OG1 . THR A 1 92  ? 139.257 153.269 109.504 1.00 117.81 ?  68   THR Q OG1 1 
ATOM 239  C CG2 . THR A 1 92  ? 137.949 153.076 107.492 1.00 117.81 ?  68   THR Q CG2 1 
ATOM 240  N N   . PRO A 1 93  ? 135.185 154.998 108.109 1.00 110.09 ?  69   PRO Q N   1 
ATOM 241  C CA  . PRO A 1 93  ? 133.839 154.900 107.518 1.00 110.09 ?  69   PRO Q CA  1 
ATOM 242  C C   . PRO A 1 93  ? 133.641 153.675 106.644 1.00 110.09 ?  69   PRO Q C   1 
ATOM 243  O O   . PRO A 1 93  ? 132.495 153.264 106.426 1.00 110.09 ?  69   PRO Q O   1 
ATOM 244  C CB  . PRO A 1 93  ? 133.713 156.186 106.688 1.00 110.09 ?  69   PRO Q CB  1 
ATOM 245  C CG  . PRO A 1 93  ? 134.863 157.056 107.060 1.00 110.09 ?  69   PRO Q CG  1 
ATOM 246  C CD  . PRO A 1 93  ? 135.739 156.359 108.044 1.00 110.09 ?  69   PRO Q CD  1 
ATOM 247  N N   . ALA A 1 94  ? 134.716 153.088 106.116 1.00 113.66 ?  70   ALA Q N   1 
ATOM 248  C CA  . ALA A 1 94  ? 134.568 151.957 105.210 1.00 113.66 ?  70   ALA Q CA  1 
ATOM 249  C C   . ALA A 1 94  ? 134.156 150.678 105.926 1.00 113.66 ?  70   ALA Q C   1 
ATOM 250  O O   . ALA A 1 94  ? 133.656 149.754 105.276 1.00 113.66 ?  70   ALA Q O   1 
ATOM 251  C CB  . ALA A 1 94  ? 135.870 151.724 104.443 1.00 113.66 ?  70   ALA Q CB  1 
ATOM 252  N N   . PHE A 1 95  ? 134.353 150.599 107.238 1.00 113.65 ?  71   PHE Q N   1 
ATOM 253  C CA  . PHE A 1 95  ? 134.084 149.375 107.992 1.00 113.65 ?  71   PHE Q CA  1 
ATOM 254  C C   . PHE A 1 95  ? 132.699 149.421 108.639 1.00 113.65 ?  71   PHE Q C   1 
ATOM 255  O O   . PHE A 1 95  ? 132.546 149.318 109.855 1.00 113.65 ?  71   PHE Q O   1 
ATOM 256  C CB  . PHE A 1 95  ? 135.173 149.153 109.035 1.00 113.65 ?  71   PHE Q CB  1 
ATOM 257  C CG  . PHE A 1 95  ? 136.470 148.663 108.462 1.00 113.65 ?  71   PHE Q CG  1 
ATOM 258  C CD1 . PHE A 1 95  ? 136.552 148.258 107.141 1.00 113.65 ?  71   PHE Q CD1 1 
ATOM 259  C CD2 . PHE A 1 95  ? 137.610 148.605 109.247 1.00 113.65 ?  71   PHE Q CD2 1 
ATOM 260  C CE1 . PHE A 1 95  ? 137.747 147.806 106.612 1.00 113.65 ?  71   PHE Q CE1 1 
ATOM 261  C CE2 . PHE A 1 95  ? 138.807 148.154 108.725 1.00 113.65 ?  71   PHE Q CE2 1 
ATOM 262  C CZ  . PHE A 1 95  ? 138.876 147.754 107.406 1.00 113.65 ?  71   PHE Q CZ  1 
ATOM 263  N N   . ARG A 1 96  ? 131.676 149.580 107.801 1.00 108.42 ?  72   ARG Q N   1 
ATOM 264  C CA  . ARG A 1 96  ? 130.283 149.501 108.229 1.00 108.42 ?  72   ARG Q CA  1 
ATOM 265  C C   . ARG A 1 96  ? 129.579 148.276 107.656 1.00 108.42 ?  72   ARG Q C   1 
ATOM 266  O O   . ARG A 1 96  ? 128.361 148.285 107.468 1.00 108.42 ?  72   ARG Q O   1 
ATOM 267  C CB  . ARG A 1 96  ? 129.508 150.766 107.856 1.00 108.42 ?  72   ARG Q CB  1 
ATOM 268  C CG  . ARG A 1 96  ? 130.171 152.105 108.171 1.00 108.42 ?  72   ARG Q CG  1 
ATOM 269  C CD  . ARG A 1 96  ? 130.899 152.107 109.509 1.00 108.42 ?  72   ARG Q CD  1 
ATOM 270  N NE  . ARG A 1 96  ? 131.702 153.309 109.692 1.00 108.42 ?  72   ARG Q NE  1 
ATOM 271  C CZ  . ARG A 1 96  ? 132.442 153.561 110.764 1.00 108.42 ?  72   ARG Q CZ  1 
ATOM 272  N NH1 . ARG A 1 96  ? 132.495 152.718 111.781 1.00 108.42 1  72   ARG Q NH1 1 
ATOM 273  N NH2 . ARG A 1 96  ? 133.146 154.688 110.816 1.00 108.42 ?  72   ARG Q NH2 1 
ATOM 274  N N   . ALA A 1 97  ? 130.331 147.217 107.375 1.00 104.32 ?  73   ALA Q N   1 
ATOM 275  C CA  . ALA A 1 97  ? 129.729 146.001 106.863 1.00 104.32 ?  73   ALA Q CA  1 
ATOM 276  C C   . ALA A 1 97  ? 128.847 145.360 107.934 1.00 104.32 ?  73   ALA Q C   1 
ATOM 277  O O   . ALA A 1 97  ? 129.052 145.582 109.130 1.00 104.32 ?  73   ALA Q O   1 
ATOM 278  C CB  . ALA A 1 97  ? 130.808 145.019 106.416 1.00 104.32 ?  73   ALA Q CB  1 
ATOM 279  N N   . PRO A 1 98  ? 127.845 144.573 107.530 1.00 95.72  ?  74   PRO Q N   1 
ATOM 280  C CA  . PRO A 1 98  ? 126.979 143.928 108.530 1.00 95.72  ?  74   PRO Q CA  1 
ATOM 281  C C   . PRO A 1 98  ? 127.732 143.057 109.519 1.00 95.72  ?  74   PRO Q C   1 
ATOM 282  O O   . PRO A 1 98  ? 127.326 142.972 110.685 1.00 95.72  ?  74   PRO Q O   1 
ATOM 283  C CB  . PRO A 1 98  ? 126.014 143.102 107.671 1.00 95.72  ?  74   PRO Q CB  1 
ATOM 284  C CG  . PRO A 1 98  ? 125.971 143.819 106.375 1.00 95.72  ?  74   PRO Q CG  1 
ATOM 285  C CD  . PRO A 1 98  ? 127.355 144.358 106.159 1.00 95.72  ?  74   PRO Q CD  1 
ATOM 286  N N   . MET A 1 99  ? 128.816 142.408 109.096 1.00 99.43  ?  75   MET Q N   1 
ATOM 287  C CA  . MET A 1 99  ? 129.590 141.588 110.019 1.00 99.43  ?  75   MET Q CA  1 
ATOM 288  C C   . MET A 1 99  ? 130.382 142.424 111.011 1.00 99.43  ?  75   MET Q C   1 
ATOM 289  O O   . MET A 1 99  ? 130.728 141.922 112.085 1.00 99.43  ?  75   MET Q O   1 
ATOM 290  C CB  . MET A 1 99  ? 130.505 140.642 109.229 1.00 99.43  ?  75   MET Q CB  1 
ATOM 291  C CG  . MET A 1 99  ? 131.747 141.252 108.555 1.00 99.43  ?  75   MET Q CG  1 
ATOM 292  S SD  . MET A 1 99  ? 133.087 141.887 109.587 1.00 99.43  ?  75   MET Q SD  1 
ATOM 293  C CE  . MET A 1 99  ? 133.546 140.411 110.492 1.00 99.43  ?  75   MET Q CE  1 
ATOM 294  N N   . PHE A 1 100 ? 130.679 143.682 110.682 1.00 102.20 ?  76   PHE Q N   1 
ATOM 295  C CA  . PHE A 1 100 ? 131.481 144.502 111.582 1.00 102.20 ?  76   PHE Q CA  1 
ATOM 296  C C   . PHE A 1 100 ? 130.681 144.964 112.792 1.00 102.20 ?  76   PHE Q C   1 
ATOM 297  O O   . PHE A 1 100 ? 131.263 145.250 113.847 1.00 102.20 ?  76   PHE Q O   1 
ATOM 298  C CB  . PHE A 1 100 ? 132.045 145.704 110.830 1.00 102.20 ?  76   PHE Q CB  1 
ATOM 299  C CG  . PHE A 1 100 ? 133.323 145.414 110.102 1.00 102.20 ?  76   PHE Q CG  1 
ATOM 300  C CD1 . PHE A 1 100 ? 134.430 144.941 110.784 1.00 102.20 ?  76   PHE Q CD1 1 
ATOM 301  C CD2 . PHE A 1 100 ? 133.420 145.617 108.737 1.00 102.20 ?  76   PHE Q CD2 1 
ATOM 302  C CE1 . PHE A 1 100 ? 135.609 144.673 110.118 1.00 102.20 ?  76   PHE Q CE1 1 
ATOM 303  C CE2 . PHE A 1 100 ? 134.596 145.351 108.064 1.00 102.20 ?  76   PHE Q CE2 1 
ATOM 304  C CZ  . PHE A 1 100 ? 135.692 144.879 108.756 1.00 102.20 ?  76   PHE Q CZ  1 
ATOM 305  N N   . LEU A 1 101 ? 129.357 145.049 112.661 1.00 98.37  ?  77   LEU Q N   1 
ATOM 306  C CA  . LEU A 1 101 ? 128.532 145.498 113.776 1.00 98.37  ?  77   LEU Q CA  1 
ATOM 307  C C   . LEU A 1 101 ? 128.629 144.539 114.955 1.00 98.37  ?  77   LEU Q C   1 
ATOM 308  O O   . LEU A 1 101 ? 128.700 144.969 116.113 1.00 98.37  ?  77   LEU Q O   1 
ATOM 309  C CB  . LEU A 1 101 ? 127.082 145.652 113.323 1.00 98.37  ?  77   LEU Q CB  1 
ATOM 310  C CG  . LEU A 1 101 ? 126.754 146.903 112.507 1.00 98.37  ?  77   LEU Q CG  1 
ATOM 311  C CD1 . LEU A 1 101 ? 125.252 147.146 112.477 1.00 98.37  ?  77   LEU Q CD1 1 
ATOM 312  C CD2 . LEU A 1 101 ? 127.484 148.118 113.061 1.00 98.37  ?  77   LEU Q CD2 1 
ATOM 313  N N   . LEU A 1 102 ? 128.632 143.234 114.681 1.00 90.25  ?  78   LEU Q N   1 
ATOM 314  C CA  . LEU A 1 102 ? 128.731 142.252 115.756 1.00 90.25  ?  78   LEU Q CA  1 
ATOM 315  C C   . LEU A 1 102 ? 130.081 142.337 116.459 1.00 90.25  ?  78   LEU Q C   1 
ATOM 316  O O   . LEU A 1 102 ? 130.161 142.222 117.690 1.00 90.25  ?  78   LEU Q O   1 
ATOM 317  C CB  . LEU A 1 102 ? 128.492 140.849 115.200 1.00 90.25  ?  78   LEU Q CB  1 
ATOM 318  C CG  . LEU A 1 102 ? 127.064 140.300 115.247 1.00 90.25  ?  78   LEU Q CG  1 
ATOM 319  C CD1 . LEU A 1 102 ? 126.047 141.348 114.834 1.00 90.25  ?  78   LEU Q CD1 1 
ATOM 320  C CD2 . LEU A 1 102 ? 126.940 139.070 114.368 1.00 90.25  ?  78   LEU Q CD2 1 
ATOM 321  N N   . VAL A 1 103 ? 131.155 142.532 115.692 1.00 90.10  ?  79   VAL Q N   1 
ATOM 322  C CA  . VAL A 1 103 ? 132.476 142.687 116.292 1.00 90.10  ?  79   VAL Q CA  1 
ATOM 323  C C   . VAL A 1 103 ? 132.511 143.923 117.176 1.00 90.10  ?  79   VAL Q C   1 
ATOM 324  O O   . VAL A 1 103 ? 133.067 143.901 118.282 1.00 90.10  ?  79   VAL Q O   1 
ATOM 325  C CB  . VAL A 1 103 ? 133.557 142.741 115.200 1.00 90.10  ?  79   VAL Q CB  1 
ATOM 326  C CG1 . VAL A 1 103 ? 134.935 142.848 115.828 1.00 90.10  ?  79   VAL Q CG1 1 
ATOM 327  C CG2 . VAL A 1 103 ? 133.468 141.516 114.310 1.00 90.10  ?  79   VAL Q CG2 1 
ATOM 328  N N   . GLY A 1 104 ? 131.920 145.020 116.703 1.00 93.86  ?  80   GLY Q N   1 
ATOM 329  C CA  . GLY A 1 104 ? 131.837 146.210 117.532 1.00 93.86  ?  80   GLY Q CA  1 
ATOM 330  C C   . GLY A 1 104 ? 131.059 145.971 118.810 1.00 93.86  ?  80   GLY Q C   1 
ATOM 331  O O   . GLY A 1 104 ? 131.431 146.466 119.878 1.00 93.86  ?  80   GLY Q O   1 
ATOM 332  N N   . SER A 1 105 ? 129.963 145.213 118.717 1.00 91.93  ?  81   SER Q N   1 
ATOM 333  C CA  . SER A 1 105 ? 129.168 144.907 119.902 1.00 91.93  ?  81   SER Q CA  1 
ATOM 334  C C   . SER A 1 105 ? 129.980 144.118 120.918 1.00 91.93  ?  81   SER Q C   1 
ATOM 335  O O   . SER A 1 105 ? 129.960 144.421 122.118 1.00 91.93  ?  81   SER Q O   1 
ATOM 336  C CB  . SER A 1 105 ? 127.917 144.126 119.508 1.00 91.93  ?  81   SER Q CB  1 
ATOM 337  O OG  . SER A 1 105 ? 128.152 142.733 119.601 1.00 91.93  ?  81   SER Q OG  1 
ATOM 338  N N   . LEU A 1 106 ? 130.710 143.107 120.452 1.00 87.80  ?  82   LEU Q N   1 
ATOM 339  C CA  . LEU A 1 106 ? 131.565 142.343 121.354 1.00 87.80  ?  82   LEU Q CA  1 
ATOM 340  C C   . LEU A 1 106 ? 132.620 143.235 121.995 1.00 87.80  ?  82   LEU Q C   1 
ATOM 341  O O   . LEU A 1 106 ? 132.878 143.140 123.205 1.00 87.80  ?  82   LEU Q O   1 
ATOM 342  C CB  . LEU A 1 106 ? 132.212 141.187 120.593 1.00 87.80  ?  82   LEU Q CB  1 
ATOM 343  C CG  . LEU A 1 106 ? 133.341 140.381 121.230 1.00 87.80  ?  82   LEU Q CG  1 
ATOM 344  C CD1 . LEU A 1 106 ? 133.291 138.961 120.715 1.00 87.80  ?  82   LEU Q CD1 1 
ATOM 345  C CD2 . LEU A 1 106 ? 134.684 141.002 120.891 1.00 87.80  ?  82   LEU Q CD2 1 
ATOM 346  N N   . ALA A 1 107 ? 133.238 144.109 121.201 1.00 92.81  ?  83   ALA Q N   1 
ATOM 347  C CA  . ALA A 1 107 ? 134.294 144.964 121.728 1.00 92.81  ?  83   ALA Q CA  1 
ATOM 348  C C   . ALA A 1 107 ? 133.759 145.897 122.807 1.00 92.81  ?  83   ALA Q C   1 
ATOM 349  O O   . ALA A 1 107 ? 134.373 146.051 123.871 1.00 92.81  ?  83   ALA Q O   1 
ATOM 350  C CB  . ALA A 1 107 ? 134.936 145.761 120.593 1.00 92.81  ?  83   ALA Q CB  1 
ATOM 351  N N   . VAL A 1 108 ? 132.608 146.524 122.555 1.00 93.31  ?  84   VAL Q N   1 
ATOM 352  C CA  . VAL A 1 108 ? 132.072 147.462 123.536 1.00 93.31  ?  84   VAL Q CA  1 
ATOM 353  C C   . VAL A 1 108 ? 131.613 146.719 124.783 1.00 93.31  ?  84   VAL Q C   1 
ATOM 354  O O   . VAL A 1 108 ? 131.759 147.220 125.905 1.00 93.31  ?  84   VAL Q O   1 
ATOM 355  C CB  . VAL A 1 108 ? 130.947 148.324 122.928 1.00 93.31  ?  84   VAL Q CB  1 
ATOM 356  C CG1 . VAL A 1 108 ? 129.815 147.472 122.400 1.00 93.31  ?  84   VAL Q CG1 1 
ATOM 357  C CG2 . VAL A 1 108 ? 130.433 149.332 123.948 1.00 93.31  ?  84   VAL Q CG2 1 
ATOM 358  N N   . ALA A 1 109 ? 131.073 145.508 124.620 1.00 93.76  ?  85   ALA Q N   1 
ATOM 359  C CA  . ALA A 1 109 ? 130.684 144.720 125.784 1.00 93.76  ?  85   ALA Q CA  1 
ATOM 360  C C   . ALA A 1 109 ? 131.888 144.411 126.665 1.00 93.76  ?  85   ALA Q C   1 
ATOM 361  O O   . ALA A 1 109 ? 131.831 144.554 127.893 1.00 93.76  ?  85   ALA Q O   1 
ATOM 362  C CB  . ALA A 1 109 ? 129.998 143.430 125.336 1.00 93.76  ?  85   ALA Q CB  1 
ATOM 363  N N   . ASP A 1 110 ? 132.998 143.997 126.054 1.00 104.28 ?  86   ASP Q N   1 
ATOM 364  C CA  . ASP A 1 110 ? 134.170 143.662 126.858 1.00 104.28 ?  86   ASP Q CA  1 
ATOM 365  C C   . ASP A 1 110 ? 134.789 144.906 127.489 1.00 104.28 ?  86   ASP Q C   1 
ATOM 366  O O   . ASP A 1 110 ? 135.294 144.852 128.620 1.00 104.28 ?  86   ASP Q O   1 
ATOM 367  C CB  . ASP A 1 110 ? 135.190 142.908 126.010 1.00 104.28 ?  86   ASP Q CB  1 
ATOM 368  C CG  . ASP A 1 110 ? 136.393 142.456 126.812 1.00 104.28 ?  86   ASP Q CG  1 
ATOM 369  O OD1 . ASP A 1 110 ? 136.236 142.179 128.020 1.00 104.28 ?  86   ASP Q OD1 1 
ATOM 370  O OD2 . ASP A 1 110 ? 137.498 142.380 126.235 1.00 104.28 -1 86   ASP Q OD2 1 
ATOM 371  N N   . LEU A 1 111 ? 134.760 146.038 126.780 1.00 103.54 ?  87   LEU Q N   1 
ATOM 372  C CA  . LEU A 1 111 ? 135.246 147.282 127.373 1.00 103.54 ?  87   LEU Q CA  1 
ATOM 373  C C   . LEU A 1 111 ? 134.402 147.675 128.579 1.00 103.54 ?  87   LEU Q C   1 
ATOM 374  O O   . LEU A 1 111 ? 134.931 148.125 129.604 1.00 103.54 ?  87   LEU Q O   1 
ATOM 375  C CB  . LEU A 1 111 ? 135.248 148.398 126.329 1.00 103.54 ?  87   LEU Q CB  1 
ATOM 376  C CG  . LEU A 1 111 ? 135.663 149.786 126.820 1.00 103.54 ?  87   LEU Q CG  1 
ATOM 377  C CD1 . LEU A 1 111 ? 137.092 149.769 127.339 1.00 103.54 ?  87   LEU Q CD1 1 
ATOM 378  C CD2 . LEU A 1 111 ? 135.503 150.818 125.713 1.00 103.54 ?  87   LEU Q CD2 1 
ATOM 379  N N   . LEU A 1 112 ? 133.084 147.508 128.470 1.00 96.94  ?  88   LEU Q N   1 
ATOM 380  C CA  . LEU A 1 112 ? 132.202 147.755 129.602 1.00 96.94  ?  88   LEU Q CA  1 
ATOM 381  C C   . LEU A 1 112 ? 132.529 146.826 130.762 1.00 96.94  ?  88   LEU Q C   1 
ATOM 382  O O   . LEU A 1 112 ? 132.500 147.242 131.926 1.00 96.94  ?  88   LEU Q O   1 
ATOM 383  C CB  . LEU A 1 112 ? 130.749 147.589 129.163 1.00 96.94  ?  88   LEU Q CB  1 
ATOM 384  C CG  . LEU A 1 112 ? 129.651 148.149 130.060 1.00 96.94  ?  88   LEU Q CG  1 
ATOM 385  C CD1 . LEU A 1 112 ? 128.663 148.959 129.242 1.00 96.94  ?  88   LEU Q CD1 1 
ATOM 386  C CD2 . LEU A 1 112 ? 128.945 147.009 130.757 1.00 96.94  ?  88   LEU Q CD2 1 
ATOM 387  N N   . ALA A 1 113 ? 132.843 145.564 130.465 1.00 94.65  ?  89   ALA Q N   1 
ATOM 388  C CA  . ALA A 1 113 ? 133.220 144.626 131.520 1.00 94.65  ?  89   ALA Q CA  1 
ATOM 389  C C   . ALA A 1 113 ? 134.471 145.092 132.251 1.00 94.65  ?  89   ALA Q C   1 
ATOM 390  O O   . ALA A 1 113 ? 134.534 145.066 133.487 1.00 94.65  ?  89   ALA Q O   1 
ATOM 391  C CB  . ALA A 1 113 ? 133.436 143.234 130.931 1.00 94.65  ?  89   ALA Q CB  1 
ATOM 392  N N   . GLY A 1 114 ? 135.485 145.515 131.498 1.00 100.94 ?  90   GLY Q N   1 
ATOM 393  C CA  . GLY A 1 114 ? 136.708 145.987 132.130 1.00 100.94 ?  90   GLY Q CA  1 
ATOM 394  C C   . GLY A 1 114 ? 136.484 147.228 132.974 1.00 100.94 ?  90   GLY Q C   1 
ATOM 395  O O   . GLY A 1 114 ? 137.015 147.346 134.087 1.00 100.94 ?  90   GLY Q O   1 
ATOM 396  N N   . LEU A 1 115 ? 135.697 148.172 132.453 1.00 105.31 ?  91   LEU Q N   1 
ATOM 397  C CA  . LEU A 1 115 ? 135.374 149.367 133.223 1.00 105.31 ?  91   LEU Q CA  1 
ATOM 398  C C   . LEU A 1 115 ? 134.643 149.005 134.507 1.00 105.31 ?  91   LEU Q C   1 
ATOM 399  O O   . LEU A 1 115 ? 134.929 149.562 135.574 1.00 105.31 ?  91   LEU Q O   1 
ATOM 400  C CB  . LEU A 1 115 ? 134.539 150.327 132.377 1.00 105.31 ?  91   LEU Q CB  1 
ATOM 401  C CG  . LEU A 1 115 ? 134.194 151.678 133.008 1.00 105.31 ?  91   LEU Q CG  1 
ATOM 402  C CD1 . LEU A 1 115 ? 134.503 152.813 132.043 1.00 105.31 ?  91   LEU Q CD1 1 
ATOM 403  C CD2 . LEU A 1 115 ? 132.734 151.718 133.433 1.00 105.31 ?  91   LEU Q CD2 1 
ATOM 404  N N   . GLY A 1 116 ? 133.698 148.068 134.427 1.00 103.84 ?  92   GLY Q N   1 
ATOM 405  C CA  . GLY A 1 116 ? 132.995 147.641 135.624 1.00 103.84 ?  92   GLY Q CA  1 
ATOM 406  C C   . GLY A 1 116 ? 133.920 147.010 136.645 1.00 103.84 ?  92   GLY Q C   1 
ATOM 407  O O   . GLY A 1 116 ? 133.793 147.257 137.846 1.00 103.84 ?  92   GLY Q O   1 
ATOM 408  N N   . LEU A 1 117 ? 134.867 146.192 136.184 1.00 102.43 ?  93   LEU Q N   1 
ATOM 409  C CA  . LEU A 1 117 ? 135.784 145.538 137.112 1.00 102.43 ?  93   LEU Q CA  1 
ATOM 410  C C   . LEU A 1 117 ? 136.658 146.564 137.825 1.00 102.43 ?  93   LEU Q C   1 
ATOM 411  O O   . LEU A 1 117 ? 136.824 146.515 139.053 1.00 102.43 ?  93   LEU Q O   1 
ATOM 412  C CB  . LEU A 1 117 ? 136.638 144.514 136.362 1.00 102.43 ?  93   LEU Q CB  1 
ATOM 413  C CG  . LEU A 1 117 ? 137.221 143.287 137.080 1.00 102.43 ?  93   LEU Q CG  1 
ATOM 414  C CD1 . LEU A 1 117 ? 138.073 142.480 136.112 1.00 102.43 ?  93   LEU Q CD1 1 
ATOM 415  C CD2 . LEU A 1 117 ? 138.031 143.636 138.322 1.00 102.43 ?  93   LEU Q CD2 1 
ATOM 416  N N   . VAL A 1 118 ? 137.223 147.512 137.073 1.00 99.85  ?  94   VAL Q N   1 
ATOM 417  C CA  . VAL A 1 118 ? 138.096 148.494 137.712 1.00 99.85  ?  94   VAL Q CA  1 
ATOM 418  C C   . VAL A 1 118 ? 137.292 149.400 138.640 1.00 99.85  ?  94   VAL Q C   1 
ATOM 419  O O   . VAL A 1 118 ? 137.760 149.772 139.724 1.00 99.85  ?  94   VAL Q O   1 
ATOM 420  C CB  . VAL A 1 118 ? 138.890 149.294 136.661 1.00 99.85  ?  94   VAL Q CB  1 
ATOM 421  C CG1 . VAL A 1 118 ? 137.970 150.017 135.699 1.00 99.85  ?  94   VAL Q CG1 1 
ATOM 422  C CG2 . VAL A 1 118 ? 139.836 150.275 137.341 1.00 99.85  ?  94   VAL Q CG2 1 
ATOM 423  N N   . LEU A 1 119 ? 136.059 149.743 138.256 1.00 105.23 ?  95   LEU Q N   1 
ATOM 424  C CA  . LEU A 1 119 ? 135.225 150.566 139.124 1.00 105.23 ?  95   LEU Q CA  1 
ATOM 425  C C   . LEU A 1 119 ? 134.850 149.824 140.400 1.00 105.23 ?  95   LEU Q C   1 
ATOM 426  O O   . LEU A 1 119 ? 134.779 150.428 141.473 1.00 105.23 ?  95   LEU Q O   1 
ATOM 427  C CB  . LEU A 1 119 ? 133.972 151.016 138.375 1.00 105.23 ?  95   LEU Q CB  1 
ATOM 428  C CG  . LEU A 1 119 ? 133.967 152.452 137.846 1.00 105.23 ?  95   LEU Q CG  1 
ATOM 429  C CD1 . LEU A 1 119 ? 135.163 152.702 136.939 1.00 105.23 ?  95   LEU Q CD1 1 
ATOM 430  C CD2 . LEU A 1 119 ? 132.666 152.751 137.117 1.00 105.23 ?  95   LEU Q CD2 1 
ATOM 431  N N   . HIS A 1 120 ? 134.596 148.518 140.307 1.00 101.00 ?  96   HIS Q N   1 
ATOM 432  C CA  . HIS A 1 120 ? 134.311 147.741 141.509 1.00 101.00 ?  96   HIS Q CA  1 
ATOM 433  C C   . HIS A 1 120 ? 135.522 147.689 142.432 1.00 101.00 ?  96   HIS Q C   1 
ATOM 434  O O   . HIS A 1 120 ? 135.387 147.833 143.656 1.00 101.00 ?  96   HIS Q O   1 
ATOM 435  C CB  . HIS A 1 120 ? 133.864 146.332 141.130 1.00 101.00 ?  96   HIS Q CB  1 
ATOM 436  C CG  . HIS A 1 120 ? 133.440 145.501 142.297 1.00 101.00 ?  96   HIS Q CG  1 
ATOM 437  N ND1 . HIS A 1 120 ? 134.339 144.949 143.183 1.00 101.00 ?  96   HIS Q ND1 1 
ATOM 438  C CD2 . HIS A 1 120 ? 132.213 145.120 142.721 1.00 101.00 ?  96   HIS Q CD2 1 
ATOM 439  C CE1 . HIS A 1 120 ? 133.684 144.269 144.106 1.00 101.00 ?  96   HIS Q CE1 1 
ATOM 440  N NE2 . HIS A 1 120 ? 132.392 144.356 143.848 1.00 101.00 ?  96   HIS Q NE2 1 
ATOM 441  N N   . PHE A 1 121 ? 136.715 147.485 141.866 1.00 106.46 ?  97   PHE Q N   1 
ATOM 442  C CA  . PHE A 1 121 ? 137.917 147.531 142.691 1.00 106.46 ?  97   PHE Q CA  1 
ATOM 443  C C   . PHE A 1 121 ? 138.059 148.886 143.366 1.00 106.46 ?  97   PHE Q C   1 
ATOM 444  O O   . PHE A 1 121 ? 138.455 148.969 144.533 1.00 106.46 ?  97   PHE Q O   1 
ATOM 445  C CB  . PHE A 1 121 ? 139.161 147.234 141.864 1.00 106.46 ?  97   PHE Q CB  1 
ATOM 446  C CG  . PHE A 1 121 ? 140.439 147.412 142.630 1.00 106.46 ?  97   PHE Q CG  1 
ATOM 447  C CD1 . PHE A 1 121 ? 140.587 146.862 143.892 1.00 106.46 ?  97   PHE Q CD1 1 
ATOM 448  C CD2 . PHE A 1 121 ? 141.480 148.157 142.105 1.00 106.46 ?  97   PHE Q CD2 1 
ATOM 449  C CE1 . PHE A 1 121 ? 141.755 147.030 144.604 1.00 106.46 ?  97   PHE Q CE1 1 
ATOM 450  C CE2 . PHE A 1 121 ? 142.654 148.329 142.813 1.00 106.46 ?  97   PHE Q CE2 1 
ATOM 451  C CZ  . PHE A 1 121 ? 142.790 147.765 144.065 1.00 106.46 ?  97   PHE Q CZ  1 
ATOM 452  N N   . ALA A 1 122 ? 137.751 149.962 142.642 1.00 108.12 ?  98   ALA Q N   1 
ATOM 453  C CA  . ALA A 1 122 ? 137.763 151.283 143.258 1.00 108.12 ?  98   ALA Q CA  1 
ATOM 454  C C   . ALA A 1 122 ? 136.754 151.361 144.395 1.00 108.12 ?  98   ALA Q C   1 
ATOM 455  O O   . ALA A 1 122 ? 137.037 151.936 145.450 1.00 108.12 ?  98   ALA Q O   1 
ATOM 456  C CB  . ALA A 1 122 ? 137.478 152.357 142.209 1.00 108.12 ?  98   ALA Q CB  1 
ATOM 457  N N   . ALA A 1 123 ? 135.571 150.781 144.199 1.00 108.39 ?  99   ALA Q N   1 
ATOM 458  C CA  . ALA A 1 123 ? 134.557 150.794 145.246 1.00 108.39 ?  99   ALA Q CA  1 
ATOM 459  C C   . ALA A 1 123 ? 135.024 150.044 146.483 1.00 108.39 ?  99   ALA Q C   1 
ATOM 460  O O   . ALA A 1 123 ? 134.600 150.363 147.599 1.00 108.39 ?  99   ALA Q O   1 
ATOM 461  C CB  . ALA A 1 123 ? 133.251 150.198 144.722 1.00 108.39 ?  99   ALA Q CB  1 
ATOM 462  N N   . VAL A 1 124 ? 135.890 149.049 146.312 1.00 116.65 ?  100  VAL Q N   1 
ATOM 463  C CA  . VAL A 1 124 ? 136.403 148.295 147.450 1.00 116.65 ?  100  VAL Q CA  1 
ATOM 464  C C   . VAL A 1 124 ? 137.741 148.876 147.899 1.00 116.65 ?  100  VAL Q C   1 
ATOM 465  O O   . VAL A 1 124 ? 138.406 148.327 148.786 1.00 116.65 ?  100  VAL Q O   1 
ATOM 466  C CB  . VAL A 1 124 ? 136.516 146.795 147.110 1.00 116.65 ?  100  VAL Q CB  1 
ATOM 467  C CG1 . VAL A 1 124 ? 137.822 146.487 146.385 1.00 116.65 ?  100  VAL Q CG1 1 
ATOM 468  C CG2 . VAL A 1 124 ? 136.369 145.944 148.367 1.00 116.65 ?  100  VAL Q CG2 1 
ATOM 469  N N   . PHE A 1 125 ? 138.135 150.007 147.313 1.00 121.72 ?  101  PHE Q N   1 
ATOM 470  C CA  . PHE A 1 125 ? 139.403 150.661 147.634 1.00 121.72 ?  101  PHE Q CA  1 
ATOM 471  C C   . PHE A 1 125 ? 139.148 152.128 147.960 1.00 121.72 ?  101  PHE Q C   1 
ATOM 472  O O   . PHE A 1 125 ? 138.873 152.927 147.059 1.00 121.72 ?  101  PHE Q O   1 
ATOM 473  C CB  . PHE A 1 125 ? 140.398 150.526 146.481 1.00 121.72 ?  101  PHE Q CB  1 
ATOM 474  C CG  . PHE A 1 125 ? 141.756 151.093 146.781 1.00 121.72 ?  101  PHE Q CG  1 
ATOM 475  C CD1 . PHE A 1 125 ? 142.468 150.672 147.892 1.00 121.72 ?  101  PHE Q CD1 1 
ATOM 476  C CD2 . PHE A 1 125 ? 142.326 152.039 145.945 1.00 121.72 ?  101  PHE Q CD2 1 
ATOM 477  C CE1 . PHE A 1 125 ? 143.719 151.191 148.169 1.00 121.72 ?  101  PHE Q CE1 1 
ATOM 478  C CE2 . PHE A 1 125 ? 143.577 152.561 146.216 1.00 121.72 ?  101  PHE Q CE2 1 
ATOM 479  C CZ  . PHE A 1 125 ? 144.274 152.136 147.329 1.00 121.72 ?  101  PHE Q CZ  1 
ATOM 480  N N   . CYS A 1 126 ? 139.282 152.478 149.239 1.00 120.07 ?  102  CYS Q N   1 
ATOM 481  C CA  . CYS A 1 126 ? 139.043 153.828 149.762 1.00 120.07 ?  102  CYS Q CA  1 
ATOM 482  C C   . CYS A 1 126 ? 137.806 154.474 149.140 1.00 120.07 ?  102  CYS Q C   1 
ATOM 483  O O   . CYS A 1 126 ? 137.833 155.609 148.660 1.00 120.07 ?  102  CYS Q O   1 
ATOM 484  C CB  . CYS A 1 126 ? 140.274 154.726 149.594 1.00 120.07 ?  102  CYS Q CB  1 
ATOM 485  S SG  . CYS A 1 126 ? 141.253 154.547 148.082 1.00 120.07 ?  102  CYS Q SG  1 
ATOM 486  N N   . ILE A 1 127 ? 136.704 153.727 149.146 1.00 115.96 ?  103  ILE Q N   1 
ATOM 487  C CA  . ILE A 1 127 ? 135.406 154.270 148.763 1.00 115.96 ?  103  ILE Q CA  1 
ATOM 488  C C   . ILE A 1 127 ? 134.410 153.982 149.877 1.00 115.96 ?  103  ILE Q C   1 
ATOM 489  O O   . ILE A 1 127 ? 133.723 154.888 150.360 1.00 115.96 ?  103  ILE Q O   1 
ATOM 490  C CB  . ILE A 1 127 ? 134.929 153.702 147.415 1.00 115.96 ?  103  ILE Q CB  1 
ATOM 491  C CG1 . ILE A 1 127 ? 135.478 154.548 146.264 1.00 115.96 ?  103  ILE Q CG1 1 
ATOM 492  C CG2 . ILE A 1 127 ? 133.411 153.667 147.350 1.00 115.96 ?  103  ILE Q CG2 1 
ATOM 493  C CD1 . ILE A 1 127 ? 134.986 155.979 146.269 1.00 115.96 ?  103  ILE Q CD1 1 
ATOM 494  N N   . GLY A 1 128 ? 134.327 152.721 150.292 1.00 114.91 ?  104  GLY Q N   1 
ATOM 495  C CA  . GLY A 1 128 ? 133.478 152.342 151.403 1.00 114.91 ?  104  GLY Q CA  1 
ATOM 496  C C   . GLY A 1 128 ? 132.001 152.576 151.168 1.00 114.91 ?  104  GLY Q C   1 
ATOM 497  O O   . GLY A 1 128 ? 131.309 153.127 152.028 1.00 114.91 ?  104  GLY Q O   1 
ATOM 498  N N   . SER A 1 129 ? 131.506 152.165 150.008 1.00 113.36 ?  105  SER Q N   1 
ATOM 499  C CA  . SER A 1 129 ? 130.108 152.330 149.646 1.00 113.36 ?  105  SER Q CA  1 
ATOM 500  C C   . SER A 1 129 ? 129.371 151.002 149.754 1.00 113.36 ?  105  SER Q C   1 
ATOM 501  O O   . SER A 1 129 ? 129.971 149.938 149.919 1.00 113.36 ?  105  SER Q O   1 
ATOM 502  C CB  . SER A 1 129 ? 129.981 152.891 148.229 1.00 113.36 ?  105  SER Q CB  1 
ATOM 503  O OG  . SER A 1 129 ? 130.068 151.851 147.272 1.00 113.36 ?  105  SER Q OG  1 
ATOM 504  N N   . ALA A 1 130 ? 128.045 151.079 149.659 1.00 116.73 ?  106  ALA Q N   1 
ATOM 505  C CA  . ALA A 1 130 ? 127.190 149.901 149.726 1.00 116.73 ?  106  ALA Q CA  1 
ATOM 506  C C   . ALA A 1 130 ? 126.386 149.684 148.455 1.00 116.73 ?  106  ALA Q C   1 
ATOM 507  O O   . ALA A 1 130 ? 126.416 148.585 147.889 1.00 116.73 ?  106  ALA Q O   1 
ATOM 508  C CB  . ALA A 1 130 ? 126.244 150.005 150.932 1.00 116.73 ?  106  ALA Q CB  1 
ATOM 509  N N   . GLU A 1 131 ? 125.660 150.702 147.987 1.00 117.02 ?  107  GLU Q N   1 
ATOM 510  C CA  . GLU A 1 131 ? 124.799 150.522 146.821 1.00 117.02 ?  107  GLU Q CA  1 
ATOM 511  C C   . GLU A 1 131 ? 125.608 150.467 145.531 1.00 117.02 ?  107  GLU Q C   1 
ATOM 512  O O   . GLU A 1 131 ? 125.259 149.724 144.600 1.00 117.02 ?  107  GLU Q O   1 
ATOM 513  C CB  . GLU A 1 131 ? 123.764 151.644 146.759 1.00 117.02 ?  107  GLU Q CB  1 
ATOM 514  C CG  . GLU A 1 131 ? 122.559 151.430 147.663 1.00 117.02 ?  107  GLU Q CG  1 
ATOM 515  C CD  . GLU A 1 131 ? 122.875 151.666 149.127 1.00 117.02 ?  107  GLU Q CD  1 
ATOM 516  O OE1 . GLU A 1 131 ? 123.874 152.357 149.418 1.00 117.02 ?  107  GLU Q OE1 1 
ATOM 517  O OE2 . GLU A 1 131 ? 122.125 151.160 149.988 1.00 117.02 -1 107  GLU Q OE2 1 
ATOM 518  N N   . MET A 1 132 ? 126.684 151.252 145.451 1.00 115.01 ?  108  MET Q N   1 
ATOM 519  C CA  . MET A 1 132 ? 127.495 151.262 144.241 1.00 115.01 ?  108  MET Q CA  1 
ATOM 520  C C   . MET A 1 132 ? 128.132 149.905 143.977 1.00 115.01 ?  108  MET Q C   1 
ATOM 521  O O   . MET A 1 132 ? 128.272 149.506 142.817 1.00 115.01 ?  108  MET Q O   1 
ATOM 522  C CB  . MET A 1 132 ? 128.554 152.360 144.323 1.00 115.01 ?  108  MET Q CB  1 
ATOM 523  C CG  . MET A 1 132 ? 128.212 153.467 145.300 1.00 115.01 ?  108  MET Q CG  1 
ATOM 524  S SD  . MET A 1 132 ? 126.466 153.916 145.262 1.00 115.01 ?  108  MET Q SD  1 
ATOM 525  C CE  . MET A 1 132 ? 126.451 155.103 143.921 1.00 115.01 ?  108  MET Q CE  1 
ATOM 526  N N   . SER A 1 133 ? 128.501 149.171 145.027 1.00 110.54 ?  109  SER Q N   1 
ATOM 527  C CA  . SER A 1 133 ? 129.001 147.816 144.824 1.00 110.54 ?  109  SER Q CA  1 
ATOM 528  C C   . SER A 1 133 ? 127.936 146.930 144.188 1.00 110.54 ?  109  SER Q C   1 
ATOM 529  O O   . SER A 1 133 ? 128.232 146.131 143.289 1.00 110.54 ?  109  SER Q O   1 
ATOM 530  C CB  . SER A 1 133 ? 129.471 147.226 146.153 1.00 110.54 ?  109  SER Q CB  1 
ATOM 531  O OG  . SER A 1 133 ? 128.396 147.119 147.070 1.00 110.54 ?  109  SER Q OG  1 
ATOM 532  N N   . LEU A 1 134 ? 126.687 147.066 144.638 1.00 104.14 ?  110  LEU Q N   1 
ATOM 533  C CA  . LEU A 1 134 ? 125.603 146.277 144.067 1.00 104.14 ?  110  LEU Q CA  1 
ATOM 534  C C   . LEU A 1 134 ? 125.395 146.611 142.595 1.00 104.14 ?  110  LEU Q C   1 
ATOM 535  O O   . LEU A 1 134 ? 125.285 145.712 141.748 1.00 104.14 ?  110  LEU Q O   1 
ATOM 536  C CB  . LEU A 1 134 ? 124.321 146.508 144.863 1.00 104.14 ?  110  LEU Q CB  1 
ATOM 537  C CG  . LEU A 1 134 ? 123.098 145.708 144.414 1.00 104.14 ?  110  LEU Q CG  1 
ATOM 538  C CD1 . LEU A 1 134 ? 123.342 144.216 144.577 1.00 104.14 ?  110  LEU Q CD1 1 
ATOM 539  C CD2 . LEU A 1 134 ? 121.861 146.140 145.187 1.00 104.14 ?  110  LEU Q CD2 1 
ATOM 540  N N   . VAL A 1 135 ? 125.347 147.903 142.264 1.00 102.66 ?  111  VAL Q N   1 
ATOM 541  C CA  . VAL A 1 135 ? 125.116 148.249 140.864 1.00 102.66 ?  111  VAL Q CA  1 
ATOM 542  C C   . VAL A 1 135 ? 126.310 147.841 140.007 1.00 102.66 ?  111  VAL Q C   1 
ATOM 543  O O   . VAL A 1 135 ? 126.149 147.495 138.829 1.00 102.66 ?  111  VAL Q O   1 
ATOM 544  C CB  . VAL A 1 135 ? 124.780 149.743 140.703 1.00 102.66 ?  111  VAL Q CB  1 
ATOM 545  C CG1 . VAL A 1 135 ? 123.515 150.092 141.479 1.00 102.66 ?  111  VAL Q CG1 1 
ATOM 546  C CG2 . VAL A 1 135 ? 125.939 150.619 141.120 1.00 102.66 ?  111  VAL Q CG2 1 
ATOM 547  N N   . LEU A 1 136 ? 127.518 147.850 140.575 1.00 104.29 ?  112  LEU Q N   1 
ATOM 548  C CA  . LEU A 1 136 ? 128.687 147.434 139.811 1.00 104.29 ?  112  LEU Q CA  1 
ATOM 549  C C   . LEU A 1 136 ? 128.670 145.935 139.537 1.00 104.29 ?  112  LEU Q C   1 
ATOM 550  O O   . LEU A 1 136 ? 129.031 145.497 138.437 1.00 104.29 ?  112  LEU Q O   1 
ATOM 551  C CB  . LEU A 1 136 ? 129.960 147.847 140.544 1.00 104.29 ?  112  LEU Q CB  1 
ATOM 552  C CG  . LEU A 1 136 ? 130.298 149.325 140.343 1.00 104.29 ?  112  LEU Q CG  1 
ATOM 553  C CD1 . LEU A 1 136 ? 131.368 149.791 141.317 1.00 104.29 ?  112  LEU Q CD1 1 
ATOM 554  C CD2 . LEU A 1 136 ? 130.719 149.581 138.904 1.00 104.29 ?  112  LEU Q CD2 1 
ATOM 555  N N   . VAL A 1 137 ? 128.251 145.126 140.512 1.00 97.54  ?  113  VAL Q N   1 
ATOM 556  C CA  . VAL A 1 137 ? 128.145 143.699 140.221 1.00 97.54  ?  113  VAL Q CA  1 
ATOM 557  C C   . VAL A 1 137 ? 127.044 143.454 139.192 1.00 97.54  ?  113  VAL Q C   1 
ATOM 558  O O   . VAL A 1 137 ? 127.174 142.574 138.322 1.00 97.54  ?  113  VAL Q O   1 
ATOM 559  C CB  . VAL A 1 137 ? 127.942 142.881 141.512 1.00 97.54  ?  113  VAL Q CB  1 
ATOM 560  C CG1 . VAL A 1 137 ? 126.485 142.852 141.943 1.00 97.54  ?  113  VAL Q CG1 1 
ATOM 561  C CG2 . VAL A 1 137 ? 128.476 141.468 141.330 1.00 97.54  ?  113  VAL Q CG2 1 
ATOM 562  N N   . GLY A 1 138 ? 125.968 144.244 139.241 1.00 94.64  ?  114  GLY Q N   1 
ATOM 563  C CA  . GLY A 1 138 ? 124.932 144.120 138.227 1.00 94.64  ?  114  GLY Q CA  1 
ATOM 564  C C   . GLY A 1 138 ? 125.446 144.416 136.830 1.00 94.64  ?  114  GLY Q C   1 
ATOM 565  O O   . GLY A 1 138 ? 125.176 143.672 135.880 1.00 94.64  ?  114  GLY Q O   1 
ATOM 566  N N   . VAL A 1 139 ? 126.201 145.507 136.684 1.00 89.93  ?  115  VAL Q N   1 
ATOM 567  C CA  . VAL A 1 139 ? 126.708 145.854 135.361 1.00 89.93  ?  115  VAL Q CA  1 
ATOM 568  C C   . VAL A 1 139 ? 127.758 144.844 134.909 1.00 89.93  ?  115  VAL Q C   1 
ATOM 569  O O   . VAL A 1 139 ? 127.906 144.587 133.707 1.00 89.93  ?  115  VAL Q O   1 
ATOM 570  C CB  . VAL A 1 139 ? 127.243 147.300 135.337 1.00 89.93  ?  115  VAL Q CB  1 
ATOM 571  C CG1 . VAL A 1 139 ? 128.462 147.454 136.212 1.00 89.93  ?  115  VAL Q CG1 1 
ATOM 572  C CG2 . VAL A 1 139 ? 127.538 147.743 133.918 1.00 89.93  ?  115  VAL Q CG2 1 
ATOM 573  N N   . LEU A 1 140 ? 128.490 144.241 135.847 1.00 84.60  ?  116  LEU Q N   1 
ATOM 574  C CA  . LEU A 1 140 ? 129.431 143.188 135.477 1.00 84.60  ?  116  LEU Q CA  1 
ATOM 575  C C   . LEU A 1 140 ? 128.702 141.990 134.879 1.00 84.60  ?  116  LEU Q C   1 
ATOM 576  O O   . LEU A 1 140 ? 129.123 141.432 133.851 1.00 84.60  ?  116  LEU Q O   1 
ATOM 577  C CB  . LEU A 1 140 ? 130.244 142.768 136.700 1.00 84.60  ?  116  LEU Q CB  1 
ATOM 578  C CG  . LEU A 1 140 ? 131.694 142.363 136.455 1.00 84.60  ?  116  LEU Q CG  1 
ATOM 579  C CD1 . LEU A 1 140 ? 132.544 143.592 136.197 1.00 84.60  ?  116  LEU Q CD1 1 
ATOM 580  C CD2 . LEU A 1 140 ? 132.232 141.579 137.636 1.00 84.60  ?  116  LEU Q CD2 1 
ATOM 581  N N   . ALA A 1 141 ? 127.602 141.576 135.514 1.00 82.76  ?  117  ALA Q N   1 
ATOM 582  C CA  . ALA A 1 141 ? 126.807 140.484 134.958 1.00 82.76  ?  117  ALA Q CA  1 
ATOM 583  C C   . ALA A 1 141 ? 126.257 140.856 133.587 1.00 82.76  ?  117  ALA Q C   1 
ATOM 584  O O   . ALA A 1 141 ? 126.264 140.035 132.654 1.00 82.76  ?  117  ALA Q O   1 
ATOM 585  C CB  . ALA A 1 141 ? 125.673 140.117 135.911 1.00 82.76  ?  117  ALA Q CB  1 
ATOM 586  N N   . MET A 1 142 ? 125.763 142.089 133.460 1.00 87.05  ?  118  MET Q N   1 
ATOM 587  C CA  . MET A 1 142 ? 125.357 142.637 132.170 1.00 87.05  ?  118  MET Q CA  1 
ATOM 588  C C   . MET A 1 142 ? 126.415 142.386 131.107 1.00 87.05  ?  118  MET Q C   1 
ATOM 589  O O   . MET A 1 142 ? 126.140 141.817 130.043 1.00 87.05  ?  118  MET Q O   1 
ATOM 590  C CB  . MET A 1 142 ? 125.117 144.140 132.316 1.00 87.05  ?  118  MET Q CB  1 
ATOM 591  C CG  . MET A 1 142 ? 124.442 144.800 131.141 1.00 87.05  ?  118  MET Q CG  1 
ATOM 592  S SD  . MET A 1 142 ? 123.038 143.868 130.543 1.00 87.05  ?  118  MET Q SD  1 
ATOM 593  C CE  . MET A 1 142 ? 121.738 144.941 131.128 1.00 87.05  ?  118  MET Q CE  1 
ATOM 594  N N   . ALA A 1 143 ? 127.641 142.819 131.392 1.00 80.95  ?  119  ALA Q N   1 
ATOM 595  C CA  . ALA A 1 143 ? 128.700 142.772 130.395 1.00 80.95  ?  119  ALA Q CA  1 
ATOM 596  C C   . ALA A 1 143 ? 129.058 141.341 130.018 1.00 80.95  ?  119  ALA Q C   1 
ATOM 597  O O   . ALA A 1 143 ? 129.287 141.045 128.838 1.00 80.95  ?  119  ALA Q O   1 
ATOM 598  C CB  . ALA A 1 143 ? 129.927 143.514 130.910 1.00 80.95  ?  119  ALA Q CB  1 
ATOM 599  N N   . PHE A 1 144 ? 129.132 140.440 131.001 1.00 71.67  ?  120  PHE Q N   1 
ATOM 600  C CA  . PHE A 1 144 ? 129.493 139.064 130.665 1.00 71.67  ?  120  PHE Q CA  1 
ATOM 601  C C   . PHE A 1 144 ? 128.423 138.399 129.806 1.00 71.67  ?  120  PHE Q C   1 
ATOM 602  O O   . PHE A 1 144 ? 128.742 137.707 128.823 1.00 71.67  ?  120  PHE Q O   1 
ATOM 603  C CB  . PHE A 1 144 ? 129.753 138.254 131.930 1.00 71.67  ?  120  PHE Q CB  1 
ATOM 604  C CG  . PHE A 1 144 ? 131.081 138.538 132.559 1.00 71.67  ?  120  PHE Q CG  1 
ATOM 605  C CD1 . PHE A 1 144 ? 132.104 139.086 131.815 1.00 71.67  ?  120  PHE Q CD1 1 
ATOM 606  C CD2 . PHE A 1 144 ? 131.311 138.240 133.888 1.00 71.67  ?  120  PHE Q CD2 1 
ATOM 607  C CE1 . PHE A 1 144 ? 133.325 139.345 132.386 1.00 71.67  ?  120  PHE Q CE1 1 
ATOM 608  C CE2 . PHE A 1 144 ? 132.535 138.497 134.463 1.00 71.67  ?  120  PHE Q CE2 1 
ATOM 609  C CZ  . PHE A 1 144 ? 133.542 139.050 133.710 1.00 71.67  ?  120  PHE Q CZ  1 
ATOM 610  N N   . THR A 1 145 ? 127.148 138.603 130.147 1.00 73.02  ?  121  THR Q N   1 
ATOM 611  C CA  . THR A 1 145 ? 126.091 138.040 129.315 1.00 73.02  ?  121  THR Q CA  1 
ATOM 612  C C   . THR A 1 145 ? 126.137 138.628 127.908 1.00 73.02  ?  121  THR Q C   1 
ATOM 613  O O   . THR A 1 145 ? 125.937 137.912 126.915 1.00 73.02  ?  121  THR Q O   1 
ATOM 614  C CB  . THR A 1 145 ? 124.729 138.277 129.963 1.00 73.02  ?  121  THR Q CB  1 
ATOM 615  O OG1 . THR A 1 145 ? 124.661 137.554 131.197 1.00 73.02  ?  121  THR Q OG1 1 
ATOM 616  C CG2 . THR A 1 145 ? 123.612 137.796 129.051 1.00 73.02  ?  121  THR Q CG2 1 
ATOM 617  N N   . ALA A 1 146 ? 126.432 139.926 127.803 1.00 71.14  ?  122  ALA Q N   1 
ATOM 618  C CA  . ALA A 1 146 ? 126.538 140.551 126.490 1.00 71.14  ?  122  ALA Q CA  1 
ATOM 619  C C   . ALA A 1 146 ? 127.667 139.940 125.672 1.00 71.14  ?  122  ALA Q C   1 
ATOM 620  O O   . ALA A 1 146 ? 127.522 139.731 124.463 1.00 71.14  ?  122  ALA Q O   1 
ATOM 621  C CB  . ALA A 1 146 ? 126.741 142.057 126.643 1.00 71.14  ?  122  ALA Q CB  1 
ATOM 622  N N   . SER A 1 147 ? 128.805 139.658 126.309 1.00 64.67  ?  123  SER Q N   1 
ATOM 623  C CA  . SER A 1 147 ? 129.917 139.049 125.582 1.00 64.67  ?  123  SER Q CA  1 
ATOM 624  C C   . SER A 1 147 ? 129.546 137.664 125.063 1.00 64.67  ?  123  SER Q C   1 
ATOM 625  O O   . SER A 1 147 ? 129.866 137.310 123.915 1.00 64.67  ?  123  SER Q O   1 
ATOM 626  C CB  . SER A 1 147 ? 131.153 138.967 126.472 1.00 64.67  ?  123  SER Q CB  1 
ATOM 627  O OG  . SER A 1 147 ? 131.201 137.726 127.148 1.00 64.67  ?  123  SER Q OG  1 
ATOM 628  N N   . ILE A 1 148 ? 128.871 136.862 125.892 1.00 64.61  ?  124  ILE Q N   1 
ATOM 629  C CA  . ILE A 1 148 ? 128.483 135.525 125.442 1.00 64.61  ?  124  ILE Q CA  1 
ATOM 630  C C   . ILE A 1 148 ? 127.515 135.626 124.262 1.00 64.61  ?  124  ILE Q C   1 
ATOM 631  O O   . ILE A 1 148 ? 127.622 134.877 123.273 1.00 64.61  ?  124  ILE Q O   1 
ATOM 632  C CB  . ILE A 1 148 ? 127.902 134.709 126.616 1.00 64.61  ?  124  ILE Q CB  1 
ATOM 633  C CG1 . ILE A 1 148 ? 128.389 133.272 126.546 1.00 64.61  ?  124  ILE Q CG1 1 
ATOM 634  C CG2 . ILE A 1 148 ? 126.380 134.708 126.635 1.00 64.61  ?  124  ILE Q CG2 1 
ATOM 635  C CD1 . ILE A 1 148 ? 129.868 133.167 126.720 1.00 64.61  ?  124  ILE Q CD1 1 
ATOM 636  N N   . GLY A 1 149 ? 126.585 136.583 124.324 1.00 66.94  ?  125  GLY Q N   1 
ATOM 637  C CA  . GLY A 1 149 ? 125.656 136.762 123.222 1.00 66.94  ?  125  GLY Q CA  1 
ATOM 638  C C   . GLY A 1 149 ? 126.345 137.219 121.953 1.00 66.94  ?  125  GLY Q C   1 
ATOM 639  O O   . GLY A 1 149 ? 125.970 136.813 120.849 1.00 66.94  ?  125  GLY Q O   1 
ATOM 640  N N   . SER A 1 150 ? 127.358 138.075 122.091 1.00 69.86  ?  126  SER Q N   1 
ATOM 641  C CA  . SER A 1 150 ? 128.113 138.515 120.925 1.00 69.86  ?  126  SER Q CA  1 
ATOM 642  C C   . SER A 1 150 ? 128.829 137.348 120.260 1.00 69.86  ?  126  SER Q C   1 
ATOM 643  O O   . SER A 1 150 ? 128.855 137.250 119.026 1.00 69.86  ?  126  SER Q O   1 
ATOM 644  C CB  . SER A 1 150 ? 129.109 139.600 121.324 1.00 69.86  ?  126  SER Q CB  1 
ATOM 645  O OG  . SER A 1 150 ? 128.537 140.889 121.197 1.00 69.86  ?  126  SER Q OG  1 
ATOM 646  N N   . LEU A 1 151 ? 129.419 136.452 121.058 1.00 64.74  ?  127  LEU Q N   1 
ATOM 647  C CA  . LEU A 1 151 ? 130.058 135.276 120.468 1.00 64.74  ?  127  LEU Q CA  1 
ATOM 648  C C   . LEU A 1 151 ? 129.052 134.425 119.704 1.00 64.74  ?  127  LEU Q C   1 
ATOM 649  O O   . LEU A 1 151 ? 129.321 133.987 118.573 1.00 64.74  ?  127  LEU Q O   1 
ATOM 650  C CB  . LEU A 1 151 ? 130.743 134.439 121.544 1.00 64.74  ?  127  LEU Q CB  1 
ATOM 651  C CG  . LEU A 1 151 ? 132.216 134.739 121.805 1.00 64.74  ?  127  LEU Q CG  1 
ATOM 652  C CD1 . LEU A 1 151 ? 132.837 133.650 122.659 1.00 64.74  ?  127  LEU Q CD1 1 
ATOM 653  C CD2 . LEU A 1 151 ? 132.966 134.885 120.495 1.00 64.74  ?  127  LEU Q CD2 1 
ATOM 654  N N   . LEU A 1 152 ? 127.880 134.187 120.300 1.00 59.67  ?  128  LEU Q N   1 
ATOM 655  C CA  . LEU A 1 152 ? 126.872 133.385 119.610 1.00 59.67  ?  128  LEU Q CA  1 
ATOM 656  C C   . LEU A 1 152 ? 126.433 134.043 118.304 1.00 59.67  ?  128  LEU Q C   1 
ATOM 657  O O   . LEU A 1 152 ? 126.298 133.370 117.271 1.00 59.67  ?  128  LEU Q O   1 
ATOM 658  C CB  . LEU A 1 152 ? 125.669 133.153 120.518 1.00 59.67  ?  128  LEU Q CB  1 
ATOM 659  C CG  . LEU A 1 152 ? 124.530 132.349 119.899 1.00 59.67  ?  128  LEU Q CG  1 
ATOM 660  C CD1 . LEU A 1 152 ? 125.041 131.025 119.391 1.00 59.67  ?  128  LEU Q CD1 1 
ATOM 661  C CD2 . LEU A 1 152 ? 123.421 132.139 120.905 1.00 59.67  ?  128  LEU Q CD2 1 
ATOM 662  N N   . ALA A 1 153 ? 126.209 135.359 118.329 1.00 65.08  ?  129  ALA Q N   1 
ATOM 663  C CA  . ALA A 1 153 ? 125.783 136.059 117.122 1.00 65.08  ?  129  ALA Q CA  1 
ATOM 664  C C   . ALA A 1 153 ? 126.850 135.990 116.039 1.00 65.08  ?  129  ALA Q C   1 
ATOM 665  O O   . ALA A 1 153 ? 126.535 135.793 114.857 1.00 65.08  ?  129  ALA Q O   1 
ATOM 666  C CB  . ALA A 1 153 ? 125.442 137.511 117.449 1.00 65.08  ?  129  ALA Q CB  1 
ATOM 667  N N   . ILE A 1 154 ? 128.119 136.148 116.420 1.00 64.68  ?  130  ILE Q N   1 
ATOM 668  C CA  . ILE A 1 154 ? 129.199 136.092 115.440 1.00 64.68  ?  130  ILE Q CA  1 
ATOM 669  C C   . ILE A 1 154 ? 129.236 134.725 114.772 1.00 64.68  ?  130  ILE Q C   1 
ATOM 670  O O   . ILE A 1 154 ? 129.353 134.615 113.542 1.00 64.68  ?  130  ILE Q O   1 
ATOM 671  C CB  . ILE A 1 154 ? 130.543 136.435 116.104 1.00 64.68  ?  130  ILE Q CB  1 
ATOM 672  C CG1 . ILE A 1 154 ? 130.734 137.949 116.160 1.00 64.68  ?  130  ILE Q CG1 1 
ATOM 673  C CG2 . ILE A 1 154 ? 131.691 135.787 115.353 1.00 64.68  ?  130  ILE Q CG2 1 
ATOM 674  C CD1 . ILE A 1 154 ? 131.315 138.542 114.895 1.00 64.68  ?  130  ILE Q CD1 1 
ATOM 675  N N   . THR A 1 155 ? 129.123 133.658 115.567 1.00 58.32  ?  131  THR Q N   1 
ATOM 676  C CA  . THR A 1 155 ? 129.222 132.333 114.963 1.00 58.32  ?  131  THR Q CA  1 
ATOM 677  C C   . THR A 1 155 ? 128.016 132.036 114.076 1.00 58.32  ?  131  THR Q C   1 
ATOM 678  O O   . THR A 1 155 ? 128.160 131.402 113.020 1.00 58.32  ?  131  THR Q O   1 
ATOM 679  C CB  . THR A 1 155 ? 129.409 131.255 116.031 1.00 58.32  ?  131  THR Q CB  1 
ATOM 680  O OG1 . THR A 1 155 ? 129.979 130.089 115.427 1.00 58.32  ?  131  THR Q OG1 1 
ATOM 681  C CG2 . THR A 1 155 ? 128.094 130.868 116.678 1.00 58.32  ?  131  THR Q CG2 1 
ATOM 682  N N   . VAL A 1 156 ? 126.824 132.507 114.458 1.00 62.03  ?  132  VAL Q N   1 
ATOM 683  C CA  . VAL A 1 156 ? 125.668 132.248 113.604 1.00 62.03  ?  132  VAL Q CA  1 
ATOM 684  C C   . VAL A 1 156 ? 125.777 133.036 112.304 1.00 62.03  ?  132  VAL Q C   1 
ATOM 685  O O   . VAL A 1 156 ? 125.387 132.541 111.235 1.00 62.03  ?  132  VAL Q O   1 
ATOM 686  C CB  . VAL A 1 156 ? 124.349 132.528 114.352 1.00 62.03  ?  132  VAL Q CB  1 
ATOM 687  C CG1 . VAL A 1 156 ? 123.961 133.996 114.291 1.00 62.03  ?  132  VAL Q CG1 1 
ATOM 688  C CG2 . VAL A 1 156 ? 123.239 131.661 113.788 1.00 62.03  ?  132  VAL Q CG2 1 
ATOM 689  N N   . ASP A 1 157 ? 126.331 134.250 112.356 1.00 66.93  ?  133  ASP Q N   1 
ATOM 690  C CA  . ASP A 1 157 ? 126.543 135.007 111.128 1.00 66.93  ?  133  ASP Q CA  1 
ATOM 691  C C   . ASP A 1 157 ? 127.529 134.298 110.213 1.00 66.93  ?  133  ASP Q C   1 
ATOM 692  O O   . ASP A 1 157 ? 127.312 134.220 108.998 1.00 66.93  ?  133  ASP Q O   1 
ATOM 693  C CB  . ASP A 1 157 ? 127.035 136.414 111.452 1.00 66.93  ?  133  ASP Q CB  1 
ATOM 694  C CG  . ASP A 1 157 ? 127.658 137.096 110.255 1.00 66.93  ?  133  ASP Q CG  1 
ATOM 695  O OD1 . ASP A 1 157 ? 126.903 137.574 109.384 1.00 66.93  ?  133  ASP Q OD1 1 
ATOM 696  O OD2 . ASP A 1 157 ? 128.903 137.149 110.182 1.00 66.93  -1 133  ASP Q OD2 1 
ATOM 697  N N   . ARG A 1 158 ? 128.617 133.769 110.777 1.00 58.44  ?  134  ARG Q N   1 
ATOM 698  C CA  . ARG A 1 158 ? 129.588 133.051 109.953 1.00 58.44  ?  134  ARG Q CA  1 
ATOM 699  C C   . ARG A 1 158 ? 128.965 131.822 109.305 1.00 58.44  ?  134  ARG Q C   1 
ATOM 700  O O   . ARG A 1 158 ? 129.210 131.538 108.123 1.00 58.44  ?  134  ARG Q O   1 
ATOM 701  C CB  . ARG A 1 158 ? 130.800 132.653 110.791 1.00 58.44  ?  134  ARG Q CB  1 
ATOM 702  C CG  . ARG A 1 158 ? 132.072 133.367 110.397 1.00 58.44  ?  134  ARG Q CG  1 
ATOM 703  C CD  . ARG A 1 158 ? 132.853 132.549 109.391 1.00 58.44  ?  134  ARG Q CD  1 
ATOM 704  N NE  . ARG A 1 158 ? 133.375 131.322 109.977 1.00 58.44  ?  134  ARG Q NE  1 
ATOM 705  C CZ  . ARG A 1 158 ? 134.419 131.267 110.792 1.00 58.44  ?  134  ARG Q CZ  1 
ATOM 706  N NH1 . ARG A 1 158 ? 135.087 132.355 111.134 1.00 58.44  1  134  ARG Q NH1 1 
ATOM 707  N NH2 . ARG A 1 158 ? 134.804 130.088 111.273 1.00 58.44  ?  134  ARG Q NH2 1 
ATOM 708  N N   . TYR A 1 159 ? 128.163 131.073 110.063 1.00 57.00  ?  135  TYR Q N   1 
ATOM 709  C CA  . TYR A 1 159 ? 127.519 129.894 109.497 1.00 57.00  ?  135  TYR Q CA  1 
ATOM 710  C C   . TYR A 1 159 ? 126.584 130.270 108.359 1.00 57.00  ?  135  TYR Q C   1 
ATOM 711  O O   . TYR A 1 159 ? 126.615 129.656 107.285 1.00 57.00  ?  135  TYR Q O   1 
ATOM 712  C CB  . TYR A 1 159 ? 126.747 129.139 110.571 1.00 57.00  ?  135  TYR Q CB  1 
ATOM 713  C CG  . TYR A 1 159 ? 125.854 128.070 109.998 1.00 57.00  ?  135  TYR Q CG  1 
ATOM 714  C CD1 . TYR A 1 159 ? 126.368 127.071 109.194 1.00 57.00  ?  135  TYR Q CD1 1 
ATOM 715  C CD2 . TYR A 1 159 ? 124.494 128.070 110.248 1.00 57.00  ?  135  TYR Q CD2 1 
ATOM 716  C CE1 . TYR A 1 159 ? 125.558 126.095 108.669 1.00 57.00  ?  135  TYR Q CE1 1 
ATOM 717  C CE2 . TYR A 1 159 ? 123.677 127.098 109.728 1.00 57.00  ?  135  TYR Q CE2 1 
ATOM 718  C CZ  . TYR A 1 159 ? 124.214 126.114 108.939 1.00 57.00  ?  135  TYR Q CZ  1 
ATOM 719  O OH  . TYR A 1 159 ? 123.397 125.142 108.415 1.00 57.00  ?  135  TYR Q OH  1 
ATOM 720  N N   . LEU A 1 160 ? 125.731 131.274 108.578 1.00 58.13  ?  136  LEU Q N   1 
ATOM 721  C CA  . LEU A 1 160 ? 124.801 131.666 107.526 1.00 58.13  ?  136  LEU Q CA  1 
ATOM 722  C C   . LEU A 1 160 ? 125.531 132.228 106.315 1.00 58.13  ?  136  LEU Q C   1 
ATOM 723  O O   . LEU A 1 160 ? 125.035 132.118 105.189 1.00 58.13  ?  136  LEU Q O   1 
ATOM 724  C CB  . LEU A 1 160 ? 123.790 132.678 108.060 1.00 58.13  ?  136  LEU Q CB  1 
ATOM 725  C CG  . LEU A 1 160 ? 122.434 132.107 108.482 1.00 58.13  ?  136  LEU Q CG  1 
ATOM 726  C CD1 . LEU A 1 160 ? 121.733 131.470 107.302 1.00 58.13  ?  136  LEU Q CD1 1 
ATOM 727  C CD2 . LEU A 1 160 ? 122.590 131.107 109.614 1.00 58.13  ?  136  LEU Q CD2 1 
ATOM 728  N N   . SER A 1 161 ? 126.704 132.826 106.517 1.00 58.77  ?  137  SER Q N   1 
ATOM 729  C CA  . SER A 1 161 ? 127.487 133.300 105.383 1.00 58.77  ?  137  SER Q CA  1 
ATOM 730  C C   . SER A 1 161 ? 128.028 132.137 104.562 1.00 58.77  ?  137  SER Q C   1 
ATOM 731  O O   . SER A 1 161 ? 127.886 132.114 103.334 1.00 58.77  ?  137  SER Q O   1 
ATOM 732  C CB  . SER A 1 161 ? 128.629 134.191 105.869 1.00 58.77  ?  137  SER Q CB  1 
ATOM 733  O OG  . SER A 1 161 ? 129.763 134.058 105.030 1.00 58.77  ?  137  SER Q OG  1 
ATOM 734  N N   . LEU A 1 162 ? 128.647 131.156 105.219 1.00 58.90  ?  138  LEU Q N   1 
ATOM 735  C CA  . LEU A 1 162 ? 129.235 130.047 104.471 1.00 58.90  ?  138  LEU Q CA  1 
ATOM 736  C C   . LEU A 1 162 ? 128.205 129.056 103.946 1.00 58.90  ?  138  LEU Q C   1 
ATOM 737  O O   . LEU A 1 162 ? 128.546 128.241 103.085 1.00 58.90  ?  138  LEU Q O   1 
ATOM 738  C CB  . LEU A 1 162 ? 130.259 129.296 105.321 1.00 58.90  ?  138  LEU Q CB  1 
ATOM 739  C CG  . LEU A 1 162 ? 131.566 130.031 105.604 1.00 58.90  ?  138  LEU Q CG  1 
ATOM 740  C CD1 . LEU A 1 162 ? 132.578 129.091 106.232 1.00 58.90  ?  138  LEU Q CD1 1 
ATOM 741  C CD2 . LEU A 1 162 ? 132.115 130.636 104.327 1.00 58.90  ?  138  LEU Q CD2 1 
ATOM 742  N N   . TYR A 1 163 ? 126.971 129.090 104.440 1.00 67.35  ?  139  TYR Q N   1 
ATOM 743  C CA  . TYR A 1 163 ? 125.950 128.181 103.934 1.00 67.35  ?  139  TYR Q CA  1 
ATOM 744  C C   . TYR A 1 163 ? 125.256 128.742 102.705 1.00 67.35  ?  139  TYR Q C   1 
ATOM 745  O O   . TYR A 1 163 ? 124.903 127.985 101.796 1.00 67.35  ?  139  TYR Q O   1 
ATOM 746  C CB  . TYR A 1 163 ? 124.935 127.870 105.043 1.00 67.35  ?  139  TYR Q CB  1 
ATOM 747  C CG  . TYR A 1 163 ? 123.676 127.113 104.637 1.00 67.35  ?  139  TYR Q CG  1 
ATOM 748  C CD1 . TYR A 1 163 ? 122.694 127.699 103.845 1.00 67.35  ?  139  TYR Q CD1 1 
ATOM 749  C CD2 . TYR A 1 163 ? 123.427 125.844 105.137 1.00 67.35  ?  139  TYR Q CD2 1 
ATOM 750  C CE1 . TYR A 1 163 ? 121.551 127.019 103.506 1.00 67.35  ?  139  TYR Q CE1 1 
ATOM 751  C CE2 . TYR A 1 163 ? 122.282 125.157 104.801 1.00 67.35  ?  139  TYR Q CE2 1 
ATOM 752  C CZ  . TYR A 1 163 ? 121.347 125.750 103.989 1.00 67.35  ?  139  TYR Q CZ  1 
ATOM 753  O OH  . TYR A 1 163 ? 120.201 125.068 103.656 1.00 67.35  ?  139  TYR Q OH  1 
ATOM 754  N N   . ASN A 1 164 ? 125.055 130.058 102.658 1.00 83.68  ?  140  ASN Q N   1 
ATOM 755  C CA  . ASN A 1 164 ? 124.277 130.669 101.590 1.00 83.68  ?  140  ASN Q CA  1 
ATOM 756  C C   . ASN A 1 164 ? 124.972 130.611 100.238 1.00 83.68  ?  140  ASN Q C   1 
ATOM 757  O O   . ASN A 1 164 ? 124.331 130.901 99.223  1.00 83.68  ?  140  ASN Q O   1 
ATOM 758  C CB  . ASN A 1 164 ? 123.963 132.119 101.944 1.00 83.68  ?  140  ASN Q CB  1 
ATOM 759  C CG  . ASN A 1 164 ? 122.721 132.627 101.256 1.00 83.68  ?  140  ASN Q CG  1 
ATOM 760  O OD1 . ASN A 1 164 ? 122.332 133.781 101.429 1.00 83.68  ?  140  ASN Q OD1 1 
ATOM 761  N ND2 . ASN A 1 164 ? 122.085 131.767 100.472 1.00 83.68  ?  140  ASN Q ND2 1 
ATOM 762  N N   . ALA A 1 165 ? 126.249 130.249 100.196 1.00 83.99  ?  141  ALA Q N   1 
ATOM 763  C CA  . ALA A 1 165 ? 126.982 130.135 98.944  1.00 83.99  ?  141  ALA Q CA  1 
ATOM 764  C C   . ALA A 1 165 ? 126.724 128.819 98.223  1.00 83.99  ?  141  ALA Q C   1 
ATOM 765  O O   . ALA A 1 165 ? 127.418 128.520 97.246  1.00 83.99  ?  141  ALA Q O   1 
ATOM 766  C CB  . ALA A 1 165 ? 128.482 130.303 99.195  1.00 83.99  ?  141  ALA Q CB  1 
ATOM 767  N N   . LEU A 1 166 ? 125.761 128.026 98.678  1.00 92.81  ?  142  LEU Q N   1 
ATOM 768  C CA  . LEU A 1 166 ? 125.402 126.779 98.016  1.00 92.81  ?  142  LEU Q CA  1 
ATOM 769  C C   . LEU A 1 166 ? 123.967 126.753 97.521  1.00 92.81  ?  142  LEU Q C   1 
ATOM 770  O O   . LEU A 1 166 ? 123.720 126.341 96.385  1.00 92.81  ?  142  LEU Q O   1 
ATOM 771  C CB  . LEU A 1 166 ? 125.638 125.593 98.959  1.00 92.81  ?  142  LEU Q CB  1 
ATOM 772  C CG  . LEU A 1 166 ? 127.104 125.230 99.198  1.00 92.81  ?  142  LEU Q CG  1 
ATOM 773  C CD1 . LEU A 1 166 ? 127.215 123.955 100.018 1.00 92.81  ?  142  LEU Q CD1 1 
ATOM 774  C CD2 . LEU A 1 166 ? 127.846 125.092 97.878  1.00 92.81  ?  142  LEU Q CD2 1 
ATOM 775  N N   . THR A 1 167 ? 123.007 127.180 98.343  1.00 98.34  ?  143  THR Q N   1 
ATOM 776  C CA  . THR A 1 167 ? 121.622 127.258 97.897  1.00 98.34  ?  143  THR Q CA  1 
ATOM 777  C C   . THR A 1 167 ? 121.387 128.441 96.965  1.00 98.34  ?  143  THR Q C   1 
ATOM 778  O O   . THR A 1 167 ? 120.435 128.414 96.177  1.00 98.34  ?  143  THR Q O   1 
ATOM 779  C CB  . THR A 1 167 ? 120.689 127.345 99.108  1.00 98.34  ?  143  THR Q CB  1 
ATOM 780  O OG1 . THR A 1 167 ? 121.079 126.368 100.082 1.00 98.34  ?  143  THR Q OG1 1 
ATOM 781  C CG2 . THR A 1 167 ? 119.245 127.079 98.702  1.00 98.34  ?  143  THR Q CG2 1 
ATOM 782  N N   . TYR A 1 168 ? 122.242 129.463 97.029  1.00 106.36 ?  144  TYR Q N   1 
ATOM 783  C CA  . TYR A 1 168 ? 122.140 130.662 96.195  1.00 106.36 ?  144  TYR Q CA  1 
ATOM 784  C C   . TYR A 1 168 ? 120.807 131.381 96.415  1.00 106.36 ?  144  TYR Q C   1 
ATOM 785  O O   . TYR A 1 168 ? 119.976 131.504 95.513  1.00 106.36 ?  144  TYR Q O   1 
ATOM 786  C CB  . TYR A 1 168 ? 122.344 130.324 94.713  1.00 106.36 ?  144  TYR Q CB  1 
ATOM 787  C CG  . TYR A 1 168 ? 123.580 129.504 94.426  1.00 106.36 ?  144  TYR Q CG  1 
ATOM 788  C CD1 . TYR A 1 168 ? 124.844 129.983 94.742  1.00 106.36 ?  144  TYR Q CD1 1 
ATOM 789  C CD2 . TYR A 1 168 ? 123.483 128.255 93.831  1.00 106.36 ?  144  TYR Q CD2 1 
ATOM 790  C CE1 . TYR A 1 168 ? 125.977 129.237 94.478  1.00 106.36 ?  144  TYR Q CE1 1 
ATOM 791  C CE2 . TYR A 1 168 ? 124.610 127.501 93.562  1.00 106.36 ?  144  TYR Q CE2 1 
ATOM 792  C CZ  . TYR A 1 168 ? 125.854 127.997 93.888  1.00 106.36 ?  144  TYR Q CZ  1 
ATOM 793  O OH  . TYR A 1 168 ? 126.979 127.251 93.623  1.00 106.36 ?  144  TYR Q OH  1 
ATOM 794  N N   . TYR A 1 169 ? 120.616 131.860 97.644  1.00 107.71 ?  145  TYR Q N   1 
ATOM 795  C CA  . TYR A 1 169 ? 119.421 132.634 97.981  1.00 107.71 ?  145  TYR Q CA  1 
ATOM 796  C C   . TYR A 1 169 ? 119.788 133.579 99.122  1.00 107.71 ?  145  TYR Q C   1 
ATOM 797  O O   . TYR A 1 169 ? 119.816 133.167 100.286 1.00 107.71 ?  145  TYR Q O   1 
ATOM 798  C CB  . TYR A 1 169 ? 118.264 131.721 98.360  1.00 107.71 ?  145  TYR Q CB  1 
ATOM 799  C CG  . TYR A 1 169 ? 116.922 132.417 98.397  1.00 107.71 ?  145  TYR Q CG  1 
ATOM 800  C CD1 . TYR A 1 169 ? 116.150 132.541 97.249  1.00 107.71 ?  145  TYR Q CD1 1 
ATOM 801  C CD2 . TYR A 1 169 ? 116.427 132.951 99.580  1.00 107.71 ?  145  TYR Q CD2 1 
ATOM 802  C CE1 . TYR A 1 169 ? 114.923 133.177 97.277  1.00 107.71 ?  145  TYR Q CE1 1 
ATOM 803  C CE2 . TYR A 1 169 ? 115.201 133.588 99.618  1.00 107.71 ?  145  TYR Q CE2 1 
ATOM 804  C CZ  . TYR A 1 169 ? 114.454 133.698 98.464  1.00 107.71 ?  145  TYR Q CZ  1 
ATOM 805  O OH  . TYR A 1 169 ? 113.233 134.332 98.497  1.00 107.71 ?  145  TYR Q OH  1 
ATOM 806  N N   . SER A 1 170 ? 120.056 134.838 98.784  1.00 112.36 ?  146  SER Q N   1 
ATOM 807  C CA  . SER A 1 170 ? 120.450 135.852 99.751  1.00 112.36 ?  146  SER Q CA  1 
ATOM 808  C C   . SER A 1 170 ? 119.506 137.042 99.668  1.00 112.36 ?  146  SER Q C   1 
ATOM 809  O O   . SER A 1 170 ? 119.214 137.539 98.576  1.00 112.36 ?  146  SER Q O   1 
ATOM 810  C CB  . SER A 1 170 ? 121.890 136.318 99.513  1.00 112.36 ?  146  SER Q CB  1 
ATOM 811  O OG  . SER A 1 170 ? 122.797 135.232 99.582  1.00 112.36 ?  146  SER Q OG  1 
ATOM 812  N N   . GLU A 1 171 ? 119.034 137.498 100.826 1.00 127.49 ?  147  GLU Q N   1 
ATOM 813  C CA  . GLU A 1 171 ? 118.154 138.656 100.881 1.00 127.49 ?  147  GLU Q CA  1 
ATOM 814  C C   . GLU A 1 171 ? 118.176 139.236 102.288 1.00 127.49 ?  147  GLU Q C   1 
ATOM 815  O O   . GLU A 1 171 ? 118.532 138.557 103.255 1.00 127.49 ?  147  GLU Q O   1 
ATOM 816  C CB  . GLU A 1 171 ? 116.720 138.296 100.477 1.00 127.49 ?  147  GLU Q CB  1 
ATOM 817  C CG  . GLU A 1 171 ? 116.093 137.201 101.328 1.00 127.49 ?  147  GLU Q CG  1 
ATOM 818  C CD  . GLU A 1 171 ? 114.712 136.803 100.844 1.00 127.49 ?  147  GLU Q CD  1 
ATOM 819  O OE1 . GLU A 1 171 ? 114.257 137.353 99.819  1.00 127.49 ?  147  GLU Q OE1 1 
ATOM 820  O OE2 . GLU A 1 171 ? 114.079 135.942 101.492 1.00 127.49 -1 147  GLU Q OE2 1 
ATOM 821  N N   . THR A 1 172 ? 117.796 140.514 102.376 1.00 124.25 ?  148  THR Q N   1 
ATOM 822  C CA  . THR A 1 172 ? 117.523 141.225 103.624 1.00 124.25 ?  148  THR Q CA  1 
ATOM 823  C C   . THR A 1 172 ? 118.767 141.478 104.468 1.00 124.25 ?  148  THR Q C   1 
ATOM 824  O O   . THR A 1 172 ? 119.697 140.665 104.495 1.00 124.25 ?  148  THR Q O   1 
ATOM 825  C CB  . THR A 1 172 ? 116.482 140.478 104.470 1.00 124.25 ?  148  THR Q CB  1 
ATOM 826  O OG1 . THR A 1 172 ? 117.050 139.267 104.986 1.00 124.25 ?  148  THR Q OG1 1 
ATOM 827  C CG2 . THR A 1 172 ? 115.240 140.155 103.645 1.00 124.25 ?  148  THR Q CG2 1 
ATOM 828  N N   . THR A 1 173 ? 118.781 142.618 105.160 1.00 109.51 ?  149  THR Q N   1 
ATOM 829  C CA  . THR A 1 173 ? 119.771 142.909 106.187 1.00 109.51 ?  149  THR Q CA  1 
ATOM 830  C C   . THR A 1 173 ? 119.156 143.460 107.461 1.00 109.51 ?  149  THR Q C   1 
ATOM 831  O O   . THR A 1 173 ? 119.845 143.510 108.484 1.00 109.51 ?  149  THR Q O   1 
ATOM 832  C CB  . THR A 1 173 ? 120.819 143.909 105.674 1.00 109.51 ?  149  THR Q CB  1 
ATOM 833  O OG1 . THR A 1 173 ? 121.960 143.891 106.539 1.00 109.51 ?  149  THR Q OG1 1 
ATOM 834  C CG2 . THR A 1 173 ? 120.244 145.315 105.635 1.00 109.51 ?  149  THR Q CG2 1 
ATOM 835  N N   . VAL A 1 174 ? 117.890 143.871 107.435 1.00 113.15 ?  150  VAL Q N   1 
ATOM 836  C CA  . VAL A 1 174 ? 117.214 144.355 108.630 1.00 113.15 ?  150  VAL Q CA  1 
ATOM 837  C C   . VAL A 1 174 ? 116.380 143.268 109.298 1.00 113.15 ?  150  VAL Q C   1 
ATOM 838  O O   . VAL A 1 174 ? 116.119 143.361 110.508 1.00 113.15 ?  150  VAL Q O   1 
ATOM 839  C CB  . VAL A 1 174 ? 116.330 145.578 108.305 1.00 113.15 ?  150  VAL Q CB  1 
ATOM 840  C CG1 . VAL A 1 174 ? 117.156 146.668 107.640 1.00 113.15 ?  150  VAL Q CG1 1 
ATOM 841  C CG2 . VAL A 1 174 ? 115.164 145.175 107.413 1.00 113.15 ?  150  VAL Q CG2 1 
ATOM 842  N N   . THR A 1 175 ? 115.959 142.244 108.554 1.00 111.27 ?  151  THR Q N   1 
ATOM 843  C CA  . THR A 1 175 ? 115.182 141.158 109.133 1.00 111.27 ?  151  THR Q CA  1 
ATOM 844  C C   . THR A 1 175 ? 116.044 140.236 109.986 1.00 111.27 ?  151  THR Q C   1 
ATOM 845  O O   . THR A 1 175 ? 115.534 139.622 110.929 1.00 111.27 ?  151  THR Q O   1 
ATOM 846  C CB  . THR A 1 175 ? 114.481 140.383 108.009 1.00 111.27 ?  151  THR Q CB  1 
ATOM 847  O OG1 . THR A 1 175 ? 113.351 141.133 107.549 1.00 111.27 ?  151  THR Q OG1 1 
ATOM 848  C CG2 . THR A 1 175 ? 114.004 139.012 108.470 1.00 111.27 ?  151  THR Q CG2 1 
ATOM 849  N N   . ARG A 1 176 ? 117.346 140.167 109.713 1.00 106.04 ?  152  ARG Q N   1 
ATOM 850  C CA  . ARG A 1 176 ? 118.228 139.208 110.363 1.00 106.04 ?  152  ARG Q CA  1 
ATOM 851  C C   . ARG A 1 176 ? 119.236 139.847 111.306 1.00 106.04 ?  152  ARG Q C   1 
ATOM 852  O O   . ARG A 1 176 ? 119.367 139.410 112.453 1.00 106.04 ?  152  ARG Q O   1 
ATOM 853  C CB  . ARG A 1 176 ? 118.969 138.385 109.301 1.00 106.04 ?  152  ARG Q CB  1 
ATOM 854  C CG  . ARG A 1 176 ? 119.932 137.359 109.871 1.00 106.04 ?  152  ARG Q CG  1 
ATOM 855  C CD  . ARG A 1 176 ? 119.198 136.321 110.706 1.00 106.04 ?  152  ARG Q CD  1 
ATOM 856  N NE  . ARG A 1 176 ? 117.980 135.860 110.051 1.00 106.04 ?  152  ARG Q NE  1 
ATOM 857  C CZ  . ARG A 1 176 ? 117.952 135.051 109.000 1.00 106.04 ?  152  ARG Q CZ  1 
ATOM 858  N NH1 . ARG A 1 176 ? 119.064 134.588 108.453 1.00 106.04 1  152  ARG Q NH1 1 
ATOM 859  N NH2 . ARG A 1 176 ? 116.778 134.698 108.484 1.00 106.04 ?  152  ARG Q NH2 1 
ATOM 860  N N   . THR A 1 177 ? 119.979 140.857 110.852 1.00 100.02 ?  153  THR Q N   1 
ATOM 861  C CA  . THR A 1 177 ? 121.088 141.361 111.656 1.00 100.02 ?  153  THR Q CA  1 
ATOM 862  C C   . THR A 1 177 ? 120.594 142.089 112.901 1.00 100.02 ?  153  THR Q C   1 
ATOM 863  O O   . THR A 1 177 ? 121.048 141.808 114.017 1.00 100.02 ?  153  THR Q O   1 
ATOM 864  C CB  . THR A 1 177 ? 121.977 142.274 110.815 1.00 100.02 ?  153  THR Q CB  1 
ATOM 865  O OG1 . THR A 1 177 ? 122.630 141.502 109.800 1.00 100.02 ?  153  THR Q OG1 1 
ATOM 866  C CG2 . THR A 1 177 ? 123.027 142.939 111.687 1.00 100.02 ?  153  THR Q CG2 1 
ATOM 867  N N   . TYR A 1 178 ? 119.650 143.018 112.735 1.00 101.41 ?  154  TYR Q N   1 
ATOM 868  C CA  . TYR A 1 178 ? 119.212 143.813 113.877 1.00 101.41 ?  154  TYR Q CA  1 
ATOM 869  C C   . TYR A 1 178 ? 118.339 143.016 114.834 1.00 101.41 ?  154  TYR Q C   1 
ATOM 870  O O   . TYR A 1 178 ? 118.303 143.327 116.029 1.00 101.41 ?  154  TYR Q O   1 
ATOM 871  C CB  . TYR A 1 178 ? 118.473 145.067 113.412 1.00 101.41 ?  154  TYR Q CB  1 
ATOM 872  C CG  . TYR A 1 178 ? 119.258 145.945 112.468 1.00 101.41 ?  154  TYR Q CG  1 
ATOM 873  C CD1 . TYR A 1 178 ? 120.337 146.687 112.922 1.00 101.41 ?  154  TYR Q CD1 1 
ATOM 874  C CD2 . TYR A 1 178 ? 118.908 146.051 111.133 1.00 101.41 ?  154  TYR Q CD2 1 
ATOM 875  C CE1 . TYR A 1 178 ? 121.055 147.499 112.069 1.00 101.41 ?  154  TYR Q CE1 1 
ATOM 876  C CE2 . TYR A 1 178 ? 119.620 146.860 110.271 1.00 101.41 ?  154  TYR Q CE2 1 
ATOM 877  C CZ  . TYR A 1 178 ? 120.693 147.582 110.744 1.00 101.41 ?  154  TYR Q CZ  1 
ATOM 878  O OH  . TYR A 1 178 ? 121.406 148.389 109.887 1.00 101.41 ?  154  TYR Q OH  1 
ATOM 879  N N   . VAL A 1 179 ? 117.626 141.999 114.346 1.00 100.13 ?  155  VAL Q N   1 
ATOM 880  C CA  . VAL A 1 179 ? 116.745 141.250 115.236 1.00 100.13 ?  155  VAL Q CA  1 
ATOM 881  C C   . VAL A 1 179 ? 117.560 140.488 116.274 1.00 100.13 ?  155  VAL Q C   1 
ATOM 882  O O   . VAL A 1 179 ? 117.126 140.317 117.419 1.00 100.13 ?  155  VAL Q O   1 
ATOM 883  C CB  . VAL A 1 179 ? 115.815 140.316 114.437 1.00 100.13 ?  155  VAL Q CB  1 
ATOM 884  C CG1 . VAL A 1 179 ? 116.584 139.159 113.827 1.00 100.13 ?  155  VAL Q CG1 1 
ATOM 885  C CG2 . VAL A 1 179 ? 114.692 139.804 115.324 1.00 100.13 ?  155  VAL Q CG2 1 
ATOM 886  N N   . MET A 1 180 ? 118.749 140.022 115.898 1.00 99.90  ?  156  MET Q N   1 
ATOM 887  C CA  . MET A 1 180 ? 119.614 139.316 116.832 1.00 99.90  ?  156  MET Q CA  1 
ATOM 888  C C   . MET A 1 180 ? 120.594 140.243 117.533 1.00 99.90  ?  156  MET Q C   1 
ATOM 889  O O   . MET A 1 180 ? 121.007 139.953 118.661 1.00 99.90  ?  156  MET Q O   1 
ATOM 890  C CB  . MET A 1 180 ? 120.377 138.204 116.105 1.00 99.90  ?  156  MET Q CB  1 
ATOM 891  C CG  . MET A 1 180 ? 119.623 136.884 116.040 1.00 99.90  ?  156  MET Q CG  1 
ATOM 892  S SD  . MET A 1 180 ? 119.937 135.958 114.525 1.00 99.90  ?  156  MET Q SD  1 
ATOM 893  C CE  . MET A 1 180 ? 118.379 135.095 114.319 1.00 99.90  ?  156  MET Q CE  1 
ATOM 894  N N   . LEU A 1 181 ? 120.977 141.353 116.896 1.00 92.89  ?  157  LEU Q N   1 
ATOM 895  C CA  . LEU A 1 181 ? 121.842 142.316 117.566 1.00 92.89  ?  157  LEU Q CA  1 
ATOM 896  C C   . LEU A 1 181 ? 121.106 143.023 118.694 1.00 92.89  ?  157  LEU Q C   1 
ATOM 897  O O   . LEU A 1 181 ? 121.713 143.363 119.714 1.00 92.89  ?  157  LEU Q O   1 
ATOM 898  C CB  . LEU A 1 181 ? 122.374 143.331 116.556 1.00 92.89  ?  157  LEU Q CB  1 
ATOM 899  C CG  . LEU A 1 181 ? 123.401 144.381 116.993 1.00 92.89  ?  157  LEU Q CG  1 
ATOM 900  C CD1 . LEU A 1 181 ? 124.312 143.873 118.100 1.00 92.89  ?  157  LEU Q CD1 1 
ATOM 901  C CD2 . LEU A 1 181 ? 124.220 144.851 115.799 1.00 92.89  ?  157  LEU Q CD2 1 
ATOM 902  N N   . ALA A 1 182 ? 119.807 143.256 118.533 1.00 93.31  ?  158  ALA Q N   1 
ATOM 903  C CA  . ALA A 1 182 ? 119.012 143.878 119.580 1.00 93.31  ?  158  ALA Q CA  1 
ATOM 904  C C   . ALA A 1 182 ? 118.496 142.881 120.605 1.00 93.31  ?  158  ALA Q C   1 
ATOM 905  O O   . ALA A 1 182 ? 117.987 143.300 121.650 1.00 93.31  ?  158  ALA Q O   1 
ATOM 906  C CB  . ALA A 1 182 ? 117.830 144.637 118.968 1.00 93.31  ?  158  ALA Q CB  1 
ATOM 907  N N   . LEU A 1 183 ? 118.606 141.583 120.339 1.00 93.03  ?  159  LEU Q N   1 
ATOM 908  C CA  . LEU A 1 183 ? 118.158 140.575 121.286 1.00 93.03  ?  159  LEU Q CA  1 
ATOM 909  C C   . LEU A 1 183 ? 119.262 140.089 122.215 1.00 93.03  ?  159  LEU Q C   1 
ATOM 910  O O   . LEU A 1 183 ? 118.973 139.330 123.145 1.00 93.03  ?  159  LEU Q O   1 
ATOM 911  C CB  . LEU A 1 183 ? 117.559 139.376 120.545 1.00 93.03  ?  159  LEU Q CB  1 
ATOM 912  C CG  . LEU A 1 183 ? 116.332 138.734 121.196 1.00 93.03  ?  159  LEU Q CG  1 
ATOM 913  C CD1 . LEU A 1 183 ? 115.100 139.605 121.001 1.00 93.03  ?  159  LEU Q CD1 1 
ATOM 914  C CD2 . LEU A 1 183 ? 116.098 137.332 120.656 1.00 93.03  ?  159  LEU Q CD2 1 
ATOM 915  N N   . VAL A 1 184 ? 120.506 140.495 121.995 1.00 85.90  ?  160  VAL Q N   1 
ATOM 916  C CA  . VAL A 1 184 ? 121.616 140.096 122.851 1.00 85.90  ?  160  VAL Q CA  1 
ATOM 917  C C   . VAL A 1 184 ? 121.910 141.148 123.911 1.00 85.90  ?  160  VAL Q C   1 
ATOM 918  O O   . VAL A 1 184 ? 122.062 140.824 125.089 1.00 85.90  ?  160  VAL Q O   1 
ATOM 919  C CB  . VAL A 1 184 ? 122.867 139.771 122.004 1.00 85.90  ?  160  VAL Q CB  1 
ATOM 920  C CG1 . VAL A 1 184 ? 122.633 138.512 121.191 1.00 85.90  ?  160  VAL Q CG1 1 
ATOM 921  C CG2 . VAL A 1 184 ? 123.220 140.922 121.082 1.00 85.90  ?  160  VAL Q CG2 1 
ATOM 922  N N   . TRP A 1 185 ? 121.991 142.418 123.517 1.00 81.65  ?  161  TRP Q N   1 
ATOM 923  C CA  . TRP A 1 185 ? 122.074 143.481 124.507 1.00 81.65  ?  161  TRP Q CA  1 
ATOM 924  C C   . TRP A 1 185 ? 120.738 143.680 125.205 1.00 81.65  ?  161  TRP Q C   1 
ATOM 925  O O   . TRP A 1 185 ? 120.687 143.812 126.433 1.00 81.65  ?  161  TRP Q O   1 
ATOM 926  C CB  . TRP A 1 185 ? 122.529 144.779 123.849 1.00 81.65  ?  161  TRP Q CB  1 
ATOM 927  C CG  . TRP A 1 185 ? 123.990 144.843 123.622 1.00 81.65  ?  161  TRP Q CG  1 
ATOM 928  C CD1 . TRP A 1 185 ? 124.665 144.388 122.533 1.00 81.65  ?  161  TRP Q CD1 1 
ATOM 929  C CD2 . TRP A 1 185 ? 124.969 145.403 124.498 1.00 81.65  ?  161  TRP Q CD2 1 
ATOM 930  N NE1 . TRP A 1 185 ? 126.009 144.625 122.677 1.00 81.65  ?  161  TRP Q NE1 1 
ATOM 931  C CE2 . TRP A 1 185 ? 126.220 145.249 123.877 1.00 81.65  ?  161  TRP Q CE2 1 
ATOM 932  C CE3 . TRP A 1 185 ? 124.909 146.019 125.748 1.00 81.65  ?  161  TRP Q CE3 1 
ATOM 933  C CZ2 . TRP A 1 185 ? 127.402 145.688 124.463 1.00 81.65  ?  161  TRP Q CZ2 1 
ATOM 934  C CZ3 . TRP A 1 185 ? 126.082 146.453 126.329 1.00 81.65  ?  161  TRP Q CZ3 1 
ATOM 935  C CH2 . TRP A 1 185 ? 127.313 146.285 125.687 1.00 81.65  ?  161  TRP Q CH2 1 
ATOM 936  N N   . GLY A 1 186 ? 119.647 143.700 124.438 1.00 97.28  ?  162  GLY Q N   1 
ATOM 937  C CA  . GLY A 1 186 ? 118.331 143.816 125.036 1.00 97.28  ?  162  GLY Q CA  1 
ATOM 938  C C   . GLY A 1 186 ? 117.943 142.604 125.856 1.00 97.28  ?  162  GLY Q C   1 
ATOM 939  O O   . GLY A 1 186 ? 117.300 142.738 126.901 1.00 97.28  ?  162  GLY Q O   1 
ATOM 940  N N   . GLY A 1 187 ? 118.317 141.409 125.398 1.00 98.78  ?  163  GLY Q N   1 
ATOM 941  C CA  . GLY A 1 187 ? 118.043 140.210 126.167 1.00 98.78  ?  163  GLY Q CA  1 
ATOM 942  C C   . GLY A 1 187 ? 118.799 140.142 127.473 1.00 98.78  ?  163  GLY Q C   1 
ATOM 943  O O   . GLY A 1 187 ? 118.315 139.527 128.428 1.00 98.78  ?  163  GLY Q O   1 
ATOM 944  N N   . ALA A 1 188 ? 119.974 140.762 127.538 1.00 96.28  ?  164  ALA Q N   1 
ATOM 945  C CA  . ALA A 1 188 ? 120.732 140.823 128.777 1.00 96.28  ?  164  ALA Q CA  1 
ATOM 946  C C   . ALA A 1 188 ? 120.174 141.845 129.755 1.00 96.28  ?  164  ALA Q C   1 
ATOM 947  O O   . ALA A 1 188 ? 120.597 141.858 130.915 1.00 96.28  ?  164  ALA Q O   1 
ATOM 948  C CB  . ALA A 1 188 ? 122.198 141.139 128.479 1.00 96.28  ?  164  ALA Q CB  1 
ATOM 949  N N   . LEU A 1 189 ? 119.242 142.695 129.319 1.00 101.49 ?  165  LEU Q N   1 
ATOM 950  C CA  . LEU A 1 189 ? 118.648 143.677 130.220 1.00 101.49 ?  165  LEU Q CA  1 
ATOM 951  C C   . LEU A 1 189 ? 117.924 142.993 131.370 1.00 101.49 ?  165  LEU Q C   1 
ATOM 952  O O   . LEU A 1 189 ? 118.080 143.377 132.535 1.00 101.49 ?  165  LEU Q O   1 
ATOM 953  C CB  . LEU A 1 189 ? 117.693 144.588 129.448 1.00 101.49 ?  165  LEU Q CB  1 
ATOM 954  C CG  . LEU A 1 189 ? 117.623 146.058 129.864 1.00 101.49 ?  165  LEU Q CG  1 
ATOM 955  C CD1 . LEU A 1 189 ? 118.977 146.727 129.709 1.00 101.49 ?  165  LEU Q CD1 1 
ATOM 956  C CD2 . LEU A 1 189 ? 116.562 146.794 129.060 1.00 101.49 ?  165  LEU Q CD2 1 
ATOM 957  N N   . GLY A 1 190 ? 117.136 141.963 131.062 1.00 103.40 ?  166  GLY Q N   1 
ATOM 958  C CA  . GLY A 1 190 ? 116.404 141.271 132.109 1.00 103.40 ?  166  GLY Q CA  1 
ATOM 959  C C   . GLY A 1 190 ? 117.323 140.580 133.096 1.00 103.40 ?  166  GLY Q C   1 
ATOM 960  O O   . GLY A 1 190 ? 117.134 140.670 134.312 1.00 103.40 ?  166  GLY Q O   1 
ATOM 961  N N   . LEU A 1 191 ? 118.344 139.892 132.586 1.00 100.94 ?  167  LEU Q N   1 
ATOM 962  C CA  . LEU A 1 191 ? 119.257 139.149 133.443 1.00 100.94 ?  167  LEU Q CA  1 
ATOM 963  C C   . LEU A 1 191 ? 120.299 140.037 134.109 1.00 100.94 ?  167  LEU Q C   1 
ATOM 964  O O   . LEU A 1 191 ? 121.059 139.545 134.949 1.00 100.94 ?  167  LEU Q O   1 
ATOM 965  C CB  . LEU A 1 191 ? 119.950 138.043 132.645 1.00 100.94 ?  167  LEU Q CB  1 
ATOM 966  C CG  . LEU A 1 191 ? 119.194 136.718 132.496 1.00 100.94 ?  167  LEU Q CG  1 
ATOM 967  C CD1 . LEU A 1 191 ? 118.900 136.111 133.859 1.00 100.94 ?  167  LEU Q CD1 1 
ATOM 968  C CD2 . LEU A 1 191 ? 117.917 136.865 131.683 1.00 100.94 ?  167  LEU Q CD2 1 
ATOM 969  N N   . GLY A 1 192 ? 120.362 141.317 133.751 1.00 100.97 ?  168  GLY Q N   1 
ATOM 970  C CA  . GLY A 1 192 ? 121.214 142.262 134.446 1.00 100.97 ?  168  GLY Q CA  1 
ATOM 971  C C   . GLY A 1 192 ? 120.435 143.157 135.389 1.00 100.97 ?  168  GLY Q C   1 
ATOM 972  O O   . GLY A 1 192 ? 121.019 143.843 136.232 1.00 100.97 ?  168  GLY Q O   1 
ATOM 973  N N   . LEU A 1 193 ? 119.109 143.167 135.241 1.00 101.46 ?  169  LEU Q N   1 
ATOM 974  C CA  . LEU A 1 193 ? 118.242 143.892 136.159 1.00 101.46 ?  169  LEU Q CA  1 
ATOM 975  C C   . LEU A 1 193 ? 117.644 143.007 137.242 1.00 101.46 ?  169  LEU Q C   1 
ATOM 976  O O   . LEU A 1 193 ? 117.262 143.523 138.297 1.00 101.46 ?  169  LEU Q O   1 
ATOM 977  C CB  . LEU A 1 193 ? 117.117 144.593 135.380 1.00 101.46 ?  169  LEU Q CB  1 
ATOM 978  C CG  . LEU A 1 193 ? 115.821 143.881 134.964 1.00 101.46 ?  169  LEU Q CG  1 
ATOM 979  C CD1 . LEU A 1 193 ? 114.773 143.824 136.077 1.00 101.46 ?  169  LEU Q CD1 1 
ATOM 980  C CD2 . LEU A 1 193 ? 115.237 144.535 133.719 1.00 101.46 ?  169  LEU Q CD2 1 
ATOM 981  N N   . LEU A 1 194 ? 117.537 141.702 137.006 1.00 101.86 ?  170  LEU Q N   1 
ATOM 982  C CA  . LEU A 1 194 ? 117.075 140.801 138.060 1.00 101.86 ?  170  LEU Q CA  1 
ATOM 983  C C   . LEU A 1 194 ? 117.971 140.802 139.293 1.00 101.86 ?  170  LEU Q C   1 
ATOM 984  O O   . LEU A 1 194 ? 117.434 140.873 140.412 1.00 101.86 ?  170  LEU Q O   1 
ATOM 985  C CB  . LEU A 1 194 ? 116.915 139.387 137.495 1.00 101.86 ?  170  LEU Q CB  1 
ATOM 986  C CG  . LEU A 1 194 ? 115.672 139.113 136.644 1.00 101.86 ?  170  LEU Q CG  1 
ATOM 987  C CD1 . LEU A 1 194 ? 115.361 137.624 136.612 1.00 101.86 ?  170  LEU Q CD1 1 
ATOM 988  C CD2 . LEU A 1 194 ? 114.475 139.903 137.155 1.00 101.86 ?  170  LEU Q CD2 1 
ATOM 989  N N   . PRO A 1 195 ? 119.304 140.720 139.189 1.00 104.63 ?  171  PRO Q N   1 
ATOM 990  C CA  . PRO A 1 195 ? 120.116 140.601 140.413 1.00 104.63 ?  171  PRO Q CA  1 
ATOM 991  C C   . PRO A 1 195 ? 120.009 141.790 141.350 1.00 104.63 ?  171  PRO Q C   1 
ATOM 992  O O   . PRO A 1 195 ? 120.308 141.644 142.541 1.00 104.63 ?  171  PRO Q O   1 
ATOM 993  C CB  . PRO A 1 195 ? 121.546 140.444 139.875 1.00 104.63 ?  171  PRO Q CB  1 
ATOM 994  C CG  . PRO A 1 195 ? 121.504 141.016 138.507 1.00 104.63 ?  171  PRO Q CG  1 
ATOM 995  C CD  . PRO A 1 195 ? 120.151 140.658 137.984 1.00 104.63 ?  171  PRO Q CD  1 
ATOM 996  N N   . VAL A 1 196 ? 119.595 142.955 140.865 1.00 100.80 ?  172  VAL Q N   1 
ATOM 997  C CA  . VAL A 1 196 ? 119.465 144.138 141.703 1.00 100.80 ?  172  VAL Q CA  1 
ATOM 998  C C   . VAL A 1 196 ? 118.024 144.358 142.148 1.00 100.80 ?  172  VAL Q C   1 
ATOM 999  O O   . VAL A 1 196 ? 117.781 144.791 143.275 1.00 100.80 ?  172  VAL Q O   1 
ATOM 1000 C CB  . VAL A 1 196 ? 120.021 145.377 140.965 1.00 100.80 ?  172  VAL Q CB  1 
ATOM 1001 C CG1 . VAL A 1 196 ? 119.437 145.478 139.566 1.00 100.80 ?  172  VAL Q CG1 1 
ATOM 1002 C CG2 . VAL A 1 196 ? 119.753 146.647 141.754 1.00 100.80 ?  172  VAL Q CG2 1 
ATOM 1003 N N   . LEU A 1 197 ? 117.058 144.048 141.284 1.00 101.52 ?  173  LEU Q N   1 
ATOM 1004 C CA  . LEU A 1 197 ? 115.671 144.409 141.558 1.00 101.52 ?  173  LEU Q CA  1 
ATOM 1005 C C   . LEU A 1 197 ? 115.131 143.669 142.778 1.00 101.52 ?  173  LEU Q C   1 
ATOM 1006 O O   . LEU A 1 197 ? 114.836 144.283 143.810 1.00 101.52 ?  173  LEU Q O   1 
ATOM 1007 C CB  . LEU A 1 197 ? 114.812 144.138 140.319 1.00 101.52 ?  173  LEU Q CB  1 
ATOM 1008 C CG  . LEU A 1 197 ? 113.340 144.554 140.355 1.00 101.52 ?  173  LEU Q CG  1 
ATOM 1009 C CD1 . LEU A 1 197 ? 112.958 145.234 139.051 1.00 101.52 ?  173  LEU Q CD1 1 
ATOM 1010 C CD2 . LEU A 1 197 ? 112.441 143.357 140.596 1.00 101.52 ?  173  LEU Q CD2 1 
ATOM 1011 N N   . ALA A 1 198 ? 115.000 142.342 142.685 1.00 101.94 ?  174  ALA Q N   1 
ATOM 1012 C CA  . ALA A 1 198 ? 114.364 141.590 143.762 1.00 101.94 ?  174  ALA Q CA  1 
ATOM 1013 C C   . ALA A 1 198 ? 115.076 140.277 144.051 1.00 101.94 ?  174  ALA Q C   1 
ATOM 1014 O O   . ALA A 1 198 ? 114.456 139.333 144.553 1.00 101.94 ?  174  ALA Q O   1 
ATOM 1015 C CB  . ALA A 1 198 ? 112.894 141.310 143.448 1.00 101.94 ?  174  ALA Q CB  1 
ATOM 1016 N N   . TRP A 1 199 ? 116.368 140.191 143.757 1.00 108.59 ?  175  TRP Q N   1 
ATOM 1017 C CA  . TRP A 1 199 ? 117.129 138.972 143.993 1.00 108.59 ?  175  TRP Q CA  1 
ATOM 1018 C C   . TRP A 1 199 ? 118.358 139.243 144.856 1.00 108.59 ?  175  TRP Q C   1 
ATOM 1019 O O   . TRP A 1 199 ? 119.422 138.663 144.633 1.00 108.59 ?  175  TRP Q O   1 
ATOM 1020 C CB  . TRP A 1 199 ? 117.535 138.325 142.669 1.00 108.59 ?  175  TRP Q CB  1 
ATOM 1021 C CG  . TRP A 1 199 ? 116.790 137.056 142.359 1.00 108.59 ?  175  TRP Q CG  1 
ATOM 1022 C CD1 . TRP A 1 199 ? 117.310 135.797 142.287 1.00 108.59 ?  175  TRP Q CD1 1 
ATOM 1023 C CD2 . TRP A 1 199 ? 115.394 136.931 142.051 1.00 108.59 ?  175  TRP Q CD2 1 
ATOM 1024 N NE1 . TRP A 1 199 ? 116.324 134.894 141.970 1.00 108.59 ?  175  TRP Q NE1 1 
ATOM 1025 C CE2 . TRP A 1 199 ? 115.139 135.565 141.818 1.00 108.59 ?  175  TRP Q CE2 1 
ATOM 1026 C CE3 . TRP A 1 199 ? 114.336 137.840 141.953 1.00 108.59 ?  175  TRP Q CE3 1 
ATOM 1027 C CZ2 . TRP A 1 199 ? 113.872 135.086 141.496 1.00 108.59 ?  175  TRP Q CZ2 1 
ATOM 1028 C CZ3 . TRP A 1 199 ? 113.078 137.363 141.637 1.00 108.59 ?  175  TRP Q CZ3 1 
ATOM 1029 C CH2 . TRP A 1 199 ? 112.856 135.999 141.411 1.00 108.59 ?  175  TRP Q CH2 1 
ATOM 1030 N N   . ASN A 1 200 ? 118.226 140.121 145.845 1.00 107.69 ?  176  ASN Q N   1 
ATOM 1031 C CA  . ASN A 1 200 ? 119.360 140.528 146.656 1.00 107.69 ?  176  ASN Q CA  1 
ATOM 1032 C C   . ASN A 1 200 ? 119.545 139.587 147.844 1.00 107.69 ?  176  ASN Q C   1 
ATOM 1033 O O   . ASN A 1 200 ? 118.739 138.690 148.097 1.00 107.69 ?  176  ASN Q O   1 
ATOM 1034 C CB  . ASN A 1 200 ? 119.185 141.972 147.121 1.00 107.69 ?  176  ASN Q CB  1 
ATOM 1035 C CG  . ASN A 1 200 ? 117.788 142.253 147.634 1.00 107.69 ?  176  ASN Q CG  1 
ATOM 1036 O OD1 . ASN A 1 200 ? 116.934 141.367 147.661 1.00 107.69 ?  176  ASN Q OD1 1 
ATOM 1037 N ND2 . ASN A 1 200 ? 117.546 143.493 148.043 1.00 107.69 ?  176  ASN Q ND2 1 
ATOM 1038 N N   . CYS A 1 201 ? 120.632 139.798 148.587 1.00 106.95 ?  177  CYS Q N   1 
ATOM 1039 C CA  . CYS A 1 201 ? 120.958 138.990 149.751 1.00 106.95 ?  177  CYS Q CA  1 
ATOM 1040 C C   . CYS A 1 201 ? 120.757 139.714 151.073 1.00 106.95 ?  177  CYS Q C   1 
ATOM 1041 O O   . CYS A 1 201 ? 120.767 139.060 152.122 1.00 106.95 ?  177  CYS Q O   1 
ATOM 1042 C CB  . CYS A 1 201 ? 122.413 138.505 149.677 1.00 106.95 ?  177  CYS Q CB  1 
ATOM 1043 S SG  . CYS A 1 201 ? 122.799 137.405 148.299 1.00 106.95 ?  177  CYS Q SG  1 
ATOM 1044 N N   . LEU A 1 202 ? 120.579 141.036 151.057 1.00 105.79 ?  178  LEU Q N   1 
ATOM 1045 C CA  . LEU A 1 202 ? 120.508 141.793 152.302 1.00 105.79 ?  178  LEU Q CA  1 
ATOM 1046 C C   . LEU A 1 202 ? 119.246 141.497 153.101 1.00 105.79 ?  178  LEU Q C   1 
ATOM 1047 O O   . LEU A 1 202 ? 119.215 141.774 154.304 1.00 105.79 ?  178  LEU Q O   1 
ATOM 1048 C CB  . LEU A 1 202 ? 120.600 143.293 152.016 1.00 105.79 ?  178  LEU Q CB  1 
ATOM 1049 C CG  . LEU A 1 202 ? 121.983 143.923 151.804 1.00 105.79 ?  178  LEU Q CG  1 
ATOM 1050 C CD1 . LEU A 1 202 ? 122.732 144.013 153.127 1.00 105.79 ?  178  LEU Q CD1 1 
ATOM 1051 C CD2 . LEU A 1 202 ? 122.820 143.191 150.760 1.00 105.79 ?  178  LEU Q CD2 1 
ATOM 1052 N N   . ASP A 1 203 ? 118.209 140.946 152.467 1.00 108.72 ?  179  ASP Q N   1 
ATOM 1053 C CA  . ASP A 1 203 ? 116.979 140.641 153.192 1.00 108.72 ?  179  ASP Q CA  1 
ATOM 1054 C C   . ASP A 1 203 ? 117.209 139.569 154.249 1.00 108.72 ?  179  ASP Q C   1 
ATOM 1055 O O   . ASP A 1 203 ? 116.686 139.668 155.365 1.00 108.72 ?  179  ASP Q O   1 
ATOM 1056 C CB  . ASP A 1 203 ? 115.888 140.204 152.217 1.00 108.72 ?  179  ASP Q CB  1 
ATOM 1057 C CG  . ASP A 1 203 ? 114.802 139.391 152.889 1.00 108.72 ?  179  ASP Q CG  1 
ATOM 1058 O OD1 . ASP A 1 203 ? 113.822 139.994 153.375 1.00 108.72 ?  179  ASP Q OD1 1 
ATOM 1059 O OD2 . ASP A 1 203 ? 114.926 138.150 152.932 1.00 108.72 -1 179  ASP Q OD2 1 
ATOM 1060 N N   . GLY A 1 204 ? 117.979 138.536 153.919 1.00 100.86 ?  180  GLY Q N   1 
ATOM 1061 C CA  . GLY A 1 204 ? 118.317 137.477 154.844 1.00 100.86 ?  180  GLY Q CA  1 
ATOM 1062 C C   . GLY A 1 204 ? 117.751 136.121 154.483 1.00 100.86 ?  180  GLY Q C   1 
ATOM 1063 O O   . GLY A 1 204 ? 118.353 135.101 154.841 1.00 100.86 ?  180  GLY Q O   1 
ATOM 1064 N N   . LEU A 1 205 ? 116.619 136.074 153.785 1.00 108.66 ?  181  LEU Q N   1 
ATOM 1065 C CA  . LEU A 1 205 ? 116.029 134.799 153.399 1.00 108.66 ?  181  LEU Q CA  1 
ATOM 1066 C C   . LEU A 1 205 ? 116.780 134.124 152.261 1.00 108.66 ?  181  LEU Q C   1 
ATOM 1067 O O   . LEU A 1 205 ? 116.787 132.890 152.180 1.00 108.66 ?  181  LEU Q O   1 
ATOM 1068 C CB  . LEU A 1 205 ? 114.563 134.994 152.999 1.00 108.66 ?  181  LEU Q CB  1 
ATOM 1069 C CG  . LEU A 1 205 ? 113.710 133.733 152.845 1.00 108.66 ?  181  LEU Q CG  1 
ATOM 1070 C CD1 . LEU A 1 205 ? 113.557 133.019 154.180 1.00 108.66 ?  181  LEU Q CD1 1 
ATOM 1071 C CD2 . LEU A 1 205 ? 112.350 134.072 152.254 1.00 108.66 ?  181  LEU Q CD2 1 
ATOM 1072 N N   . THR A 1 206 ? 117.411 134.900 151.383 1.00 100.18 ?  182  THR Q N   1 
ATOM 1073 C CA  . THR A 1 206 ? 118.125 134.325 150.251 1.00 100.18 ?  182  THR Q CA  1 
ATOM 1074 C C   . THR A 1 206 ? 119.358 133.565 150.720 1.00 100.18 ?  182  THR Q C   1 
ATOM 1075 O O   . THR A 1 206 ? 120.067 133.997 151.631 1.00 100.18 ?  182  THR Q O   1 
ATOM 1076 C CB  . THR A 1 206 ? 118.530 135.420 149.268 1.00 100.18 ?  182  THR Q CB  1 
ATOM 1077 O OG1 . THR A 1 206 ? 118.890 136.603 149.990 1.00 100.18 ?  182  THR Q OG1 1 
ATOM 1078 C CG2 . THR A 1 206 ? 117.380 135.736 148.323 1.00 100.18 ?  182  THR Q CG2 1 
ATOM 1079 N N   . THR A 1 207 ? 119.610 132.420 150.083 1.00 91.58  ?  183  THR Q N   1 
ATOM 1080 C CA  . THR A 1 207 ? 120.745 131.589 150.470 1.00 91.58  ?  183  THR Q CA  1 
ATOM 1081 C C   . THR A 1 207 ? 122.065 132.302 150.206 1.00 91.58  ?  183  THR Q C   1 
ATOM 1082 O O   . THR A 1 207 ? 122.998 132.213 151.013 1.00 91.58  ?  183  THR Q O   1 
ATOM 1083 C CB  . THR A 1 207 ? 120.683 130.254 149.729 1.00 91.58  ?  183  THR Q CB  1 
ATOM 1084 O OG1 . THR A 1 207 ? 119.771 129.379 150.405 1.00 91.58  ?  183  THR Q OG1 1 
ATOM 1085 C CG2 . THR A 1 207 ? 122.054 129.593 149.669 1.00 91.58  ?  183  THR Q CG2 1 
ATOM 1086 N N   . CYS A 1 208 ? 122.155 133.032 149.094 1.00 96.62  ?  184  CYS Q N   1 
ATOM 1087 C CA  . CYS A 1 208 ? 123.359 133.769 148.711 1.00 96.62  ?  184  CYS Q CA  1 
ATOM 1088 C C   . CYS A 1 208 ? 124.547 132.813 148.559 1.00 96.62  ?  184  CYS Q C   1 
ATOM 1089 O O   . CYS A 1 208 ? 125.510 132.825 149.327 1.00 96.62  ?  184  CYS Q O   1 
ATOM 1090 C CB  . CYS A 1 208 ? 123.662 134.888 149.714 1.00 96.62  ?  184  CYS Q CB  1 
ATOM 1091 S SG  . CYS A 1 208 ? 124.403 136.350 148.964 1.00 96.62  ?  184  CYS Q SG  1 
ATOM 1092 N N   . GLY A 1 209 ? 124.429 131.968 147.538 1.00 90.34  ?  185  GLY Q N   1 
ATOM 1093 C CA  . GLY A 1 209 ? 125.308 130.831 147.352 1.00 90.34  ?  185  GLY Q CA  1 
ATOM 1094 C C   . GLY A 1 209 ? 126.801 131.078 147.273 1.00 90.34  ?  185  GLY Q C   1 
ATOM 1095 O O   . GLY A 1 209 ? 127.531 130.688 148.189 1.00 90.34  ?  185  GLY Q O   1 
ATOM 1096 N N   . VAL A 1 210 ? 127.284 131.714 146.208 1.00 78.63  ?  186  VAL Q N   1 
ATOM 1097 C CA  . VAL A 1 210 ? 128.715 131.759 145.908 1.00 78.63  ?  186  VAL Q CA  1 
ATOM 1098 C C   . VAL A 1 210 ? 129.263 133.182 145.966 1.00 78.63  ?  186  VAL Q C   1 
ATOM 1099 O O   . VAL A 1 210 ? 130.103 133.497 146.810 1.00 78.63  ?  186  VAL Q O   1 
ATOM 1100 C CB  . VAL A 1 210 ? 129.017 131.099 144.546 1.00 78.63  ?  186  VAL Q CB  1 
ATOM 1101 C CG1 . VAL A 1 210 ? 130.513 130.924 144.370 1.00 78.63  ?  186  VAL Q CG1 1 
ATOM 1102 C CG2 . VAL A 1 210 ? 128.306 129.765 144.440 1.00 78.63  ?  186  VAL Q CG2 1 
ATOM 1103 N N   . VAL A 1 211 ? 128.806 134.053 145.076 1.00 82.33  ?  187  VAL Q N   1 
ATOM 1104 C CA  . VAL A 1 211 ? 129.340 135.405 144.960 1.00 82.33  ?  187  VAL Q CA  1 
ATOM 1105 C C   . VAL A 1 211 ? 128.417 136.351 145.713 1.00 82.33  ?  187  VAL Q C   1 
ATOM 1106 O O   . VAL A 1 211 ? 127.219 136.430 145.419 1.00 82.33  ?  187  VAL Q O   1 
ATOM 1107 C CB  . VAL A 1 211 ? 129.490 135.827 143.492 1.00 82.33  ?  187  VAL Q CB  1 
ATOM 1108 C CG1 . VAL A 1 211 ? 129.690 137.330 143.391 1.00 82.33  ?  187  VAL Q CG1 1 
ATOM 1109 C CG2 . VAL A 1 211 ? 130.648 135.088 142.846 1.00 82.33  ?  187  VAL Q CG2 1 
ATOM 1110 N N   . TYR A 1 212 ? 128.976 137.072 146.679 1.00 79.01  ?  188  TYR Q N   1 
ATOM 1111 C CA  . TYR A 1 212 ? 128.188 137.941 147.540 1.00 79.01  ?  188  TYR Q CA  1 
ATOM 1112 C C   . TYR A 1 212 ? 128.079 139.324 146.916 1.00 79.01  ?  188  TYR Q C   1 
ATOM 1113 O O   . TYR A 1 212 ? 129.111 139.947 146.641 1.00 79.01  ?  188  TYR Q O   1 
ATOM 1114 C CB  . TYR A 1 212 ? 128.822 138.040 148.916 1.00 79.01  ?  188  TYR Q CB  1 
ATOM 1115 C CG  . TYR A 1 212 ? 128.104 138.966 149.863 1.00 79.01  ?  188  TYR Q CG  1 
ATOM 1116 C CD1 . TYR A 1 212 ? 126.956 138.558 150.523 1.00 79.01  ?  188  TYR Q CD1 1 
ATOM 1117 C CD2 . TYR A 1 212 ? 128.580 140.244 150.108 1.00 79.01  ?  188  TYR Q CD2 1 
ATOM 1118 C CE1 . TYR A 1 212 ? 126.296 139.398 151.393 1.00 79.01  ?  188  TYR Q CE1 1 
ATOM 1119 C CE2 . TYR A 1 212 ? 127.928 141.093 150.975 1.00 79.01  ?  188  TYR Q CE2 1 
ATOM 1120 C CZ  . TYR A 1 212 ? 126.786 140.665 151.616 1.00 79.01  ?  188  TYR Q CZ  1 
ATOM 1121 O OH  . TYR A 1 212 ? 126.132 141.509 152.484 1.00 79.01  ?  188  TYR Q OH  1 
ATOM 1122 N N   . PRO A 1 213 ? 126.872 139.844 146.685 1.00 76.75  ?  189  PRO Q N   1 
ATOM 1123 C CA  . PRO A 1 213 ? 125.571 139.210 146.890 1.00 76.75  ?  189  PRO Q CA  1 
ATOM 1124 C C   . PRO A 1 213 ? 124.933 138.690 145.609 1.00 76.75  ?  189  PRO Q C   1 
ATOM 1125 O O   . PRO A 1 213 ? 124.710 139.447 144.672 1.00 76.75  ?  189  PRO Q O   1 
ATOM 1126 C CB  . PRO A 1 213 ? 124.750 140.348 147.498 1.00 76.75  ?  189  PRO Q CB  1 
ATOM 1127 C CG  . PRO A 1 213 ? 125.324 141.610 146.872 1.00 76.75  ?  189  PRO Q CG  1 
ATOM 1128 C CD  . PRO A 1 213 ? 126.719 141.273 146.372 1.00 76.75  ?  189  PRO Q CD  1 
ATOM 1129 N N   . LEU A 1 214 ? 124.612 137.401 145.548 1.00 79.81  ?  190  LEU Q N   1 
ATOM 1130 C CA  . LEU A 1 214 ? 123.840 136.842 144.446 1.00 79.81  ?  190  LEU Q CA  1 
ATOM 1131 C C   . LEU A 1 214 ? 123.032 135.670 144.977 1.00 79.81  ?  190  LEU Q C   1 
ATOM 1132 O O   . LEU A 1 214 ? 123.573 134.813 145.679 1.00 79.81  ?  190  LEU Q O   1 
ATOM 1133 C CB  . LEU A 1 214 ? 124.741 136.384 143.293 1.00 79.81  ?  190  LEU Q CB  1 
ATOM 1134 C CG  . LEU A 1 214 ? 125.383 137.437 142.386 1.00 79.81  ?  190  LEU Q CG  1 
ATOM 1135 C CD1 . LEU A 1 214 ? 126.486 136.819 141.542 1.00 79.81  ?  190  LEU Q CD1 1 
ATOM 1136 C CD2 . LEU A 1 214 ? 124.341 138.104 141.504 1.00 79.81  ?  190  LEU Q CD2 1 
ATOM 1137 N N   . SER A 1 215 ? 121.749 135.633 144.640 1.00 87.58  ?  191  SER Q N   1 
ATOM 1138 C CA  . SER A 1 215 ? 120.899 134.551 145.101 1.00 87.58  ?  191  SER Q CA  1 
ATOM 1139 C C   . SER A 1 215 ? 121.234 133.256 144.365 1.00 87.58  ?  191  SER Q C   1 
ATOM 1140 O O   . SER A 1 215 ? 121.856 133.253 143.299 1.00 87.58  ?  191  SER Q O   1 
ATOM 1141 C CB  . SER A 1 215 ? 119.426 134.906 144.907 1.00 87.58  ?  191  SER Q CB  1 
ATOM 1142 O OG  . SER A 1 215 ? 118.660 133.752 144.609 1.00 87.58  ?  191  SER Q OG  1 
ATOM 1143 N N   . LYS A 1 216 ? 120.817 132.139 144.960 1.00 83.45  ?  192  LYS Q N   1 
ATOM 1144 C CA  . LYS A 1 216 ? 121.047 130.839 144.340 1.00 83.45  ?  192  LYS Q CA  1 
ATOM 1145 C C   . LYS A 1 216 ? 120.287 130.707 143.027 1.00 83.45  ?  192  LYS Q C   1 
ATOM 1146 O O   . LYS A 1 216 ? 120.828 130.198 142.035 1.00 83.45  ?  192  LYS Q O   1 
ATOM 1147 C CB  . LYS A 1 216 ? 120.642 129.727 145.306 1.00 83.45  ?  192  LYS Q CB  1 
ATOM 1148 C CG  . LYS A 1 216 ? 120.957 128.327 144.820 1.00 83.45  ?  192  LYS Q CG  1 
ATOM 1149 C CD  . LYS A 1 216 ? 122.454 128.079 144.792 1.00 83.45  ?  192  LYS Q CD  1 
ATOM 1150 C CE  . LYS A 1 216 ? 122.774 126.618 145.048 1.00 83.45  ?  192  LYS Q CE  1 
ATOM 1151 N NZ  . LYS A 1 216 ? 122.613 126.262 146.481 1.00 83.45  1  192  LYS Q NZ  1 
ATOM 1152 N N   . ASN A 1 217 ? 119.035 131.165 143.001 1.00 87.99  ?  193  ASN Q N   1 
ATOM 1153 C CA  . ASN A 1 217 ? 118.189 130.955 141.831 1.00 87.99  ?  193  ASN Q CA  1 
ATOM 1154 C C   . ASN A 1 217 ? 118.730 131.690 140.611 1.00 87.99  ?  193  ASN Q C   1 
ATOM 1155 O O   . ASN A 1 217 ? 118.743 131.143 139.500 1.00 87.99  ?  193  ASN Q O   1 
ATOM 1156 C CB  . ASN A 1 217 ? 116.764 131.405 142.143 1.00 87.99  ?  193  ASN Q CB  1 
ATOM 1157 C CG  . ASN A 1 217 ? 116.295 130.933 143.503 1.00 87.99  ?  193  ASN Q CG  1 
ATOM 1158 O OD1 . ASN A 1 217 ? 116.814 129.960 144.046 1.00 87.99  ?  193  ASN Q OD1 1 
ATOM 1159 N ND2 . ASN A 1 217 ? 115.307 131.623 144.061 1.00 87.99  ?  193  ASN Q ND2 1 
ATOM 1160 N N   . HIS A 1 218 ? 119.171 132.933 140.798 1.00 88.96  ?  194  HIS Q N   1 
ATOM 1161 C CA  . HIS A 1 218 ? 119.681 133.717 139.681 1.00 88.96  ?  194  HIS Q CA  1 
ATOM 1162 C C   . HIS A 1 218 ? 120.920 133.069 139.078 1.00 88.96  ?  194  HIS Q C   1 
ATOM 1163 O O   . HIS A 1 218 ? 121.053 132.973 137.849 1.00 88.96  ?  194  HIS Q O   1 
ATOM 1164 C CB  . HIS A 1 218 ? 119.981 135.137 140.158 1.00 88.96  ?  194  HIS Q CB  1 
ATOM 1165 C CG  . HIS A 1 218 ? 120.430 136.063 139.075 1.00 88.96  ?  194  HIS Q CG  1 
ATOM 1166 N ND1 . HIS A 1 218 ? 121.754 136.386 138.875 1.00 88.96  ?  194  HIS Q ND1 1 
ATOM 1167 C CD2 . HIS A 1 218 ? 119.730 136.740 138.135 1.00 88.96  ?  194  HIS Q CD2 1 
ATOM 1168 C CE1 . HIS A 1 218 ? 121.851 137.221 137.856 1.00 88.96  ?  194  HIS Q CE1 1 
ATOM 1169 N NE2 . HIS A 1 218 ? 120.638 137.450 137.388 1.00 88.96  ?  194  HIS Q NE2 1 
ATOM 1170 N N   . LEU A 1 219 ? 121.829 132.599 139.932 1.00 78.83  ?  195  LEU Q N   1 
ATOM 1171 C CA  . LEU A 1 219 ? 123.036 131.941 139.451 1.00 78.83  ?  195  LEU Q CA  1 
ATOM 1172 C C   . LEU A 1 219 ? 122.710 130.637 138.733 1.00 78.83  ?  195  LEU Q C   1 
ATOM 1173 O O   . LEU A 1 219 ? 123.322 130.316 137.705 1.00 78.83  ?  195  LEU Q O   1 
ATOM 1174 C CB  . LEU A 1 219 ? 123.984 131.701 140.619 1.00 78.83  ?  195  LEU Q CB  1 
ATOM 1175 C CG  . LEU A 1 219 ? 125.096 132.734 140.772 1.00 78.83  ?  195  LEU Q CG  1 
ATOM 1176 C CD1 . LEU A 1 219 ? 126.098 132.299 141.824 1.00 78.83  ?  195  LEU Q CD1 1 
ATOM 1177 C CD2 . LEU A 1 219 ? 125.785 132.964 139.444 1.00 78.83  ?  195  LEU Q CD2 1 
ATOM 1178 N N   . VAL A 1 220 ? 121.741 129.878 139.252 1.00 77.69  ?  196  VAL Q N   1 
ATOM 1179 C CA  . VAL A 1 220 ? 121.342 128.640 138.588 1.00 77.69  ?  196  VAL Q CA  1 
ATOM 1180 C C   . VAL A 1 220 ? 120.779 128.934 137.203 1.00 77.69  ?  196  VAL Q C   1 
ATOM 1181 O O   . VAL A 1 220 ? 121.101 128.244 136.225 1.00 77.69  ?  196  VAL Q O   1 
ATOM 1182 C CB  . VAL A 1 220 ? 120.338 127.867 139.461 1.00 77.69  ?  196  VAL Q CB  1 
ATOM 1183 C CG1 . VAL A 1 220 ? 119.595 126.836 138.633 1.00 77.69  ?  196  VAL Q CG1 1 
ATOM 1184 C CG2 . VAL A 1 220 ? 121.060 127.202 140.616 1.00 77.69  ?  196  VAL Q CG2 1 
ATOM 1185 N N   . VAL A 1 221 ? 119.940 129.967 137.093 1.00 71.50  ?  197  VAL Q N   1 
ATOM 1186 C CA  . VAL A 1 221 ? 119.371 130.325 135.796 1.00 71.50  ?  197  VAL Q CA  1 
ATOM 1187 C C   . VAL A 1 221 ? 120.471 130.728 134.822 1.00 71.50  ?  197  VAL Q C   1 
ATOM 1188 O O   . VAL A 1 221 ? 120.465 130.327 133.646 1.00 71.50  ?  197  VAL Q O   1 
ATOM 1189 C CB  . VAL A 1 221 ? 118.324 131.439 135.965 1.00 71.50  ?  197  VAL Q CB  1 
ATOM 1190 C CG1 . VAL A 1 221 ? 117.977 132.051 134.620 1.00 71.50  ?  197  VAL Q CG1 1 
ATOM 1191 C CG2 . VAL A 1 221 ? 117.079 130.890 136.637 1.00 71.50  ?  197  VAL Q CG2 1 
ATOM 1192 N N   . LEU A 1 222 ? 121.436 131.519 135.296 1.00 72.69  ?  198  LEU Q N   1 
ATOM 1193 C CA  . LEU A 1 222 ? 122.549 131.910 134.438 1.00 72.69  ?  198  LEU Q CA  1 
ATOM 1194 C C   . LEU A 1 222 ? 123.317 130.691 133.937 1.00 72.69  ?  198  LEU Q C   1 
ATOM 1195 O O   . LEU A 1 222 ? 123.669 130.611 132.751 1.00 72.69  ?  198  LEU Q O   1 
ATOM 1196 C CB  . LEU A 1 222 ? 123.482 132.855 135.192 1.00 72.69  ?  198  LEU Q CB  1 
ATOM 1197 C CG  . LEU A 1 222 ? 123.381 134.334 134.832 1.00 72.69  ?  198  LEU Q CG  1 
ATOM 1198 C CD1 . LEU A 1 222 ? 122.024 134.877 135.222 1.00 72.69  ?  198  LEU Q CD1 1 
ATOM 1199 C CD2 . LEU A 1 222 ? 124.490 135.124 135.503 1.00 72.69  ?  198  LEU Q CD2 1 
ATOM 1200 N N   . ALA A 1 223 ? 123.577 129.727 134.822 1.00 72.89  ?  199  ALA Q N   1 
ATOM 1201 C CA  . ALA A 1 223 ? 124.317 128.537 134.415 1.00 72.89  ?  199  ALA Q CA  1 
ATOM 1202 C C   . ALA A 1 223 ? 123.541 127.713 133.393 1.00 72.89  ?  199  ALA Q C   1 
ATOM 1203 O O   . ALA A 1 223 ? 124.130 127.166 132.448 1.00 72.89  ?  199  ALA Q O   1 
ATOM 1204 C CB  . ALA A 1 223 ? 124.658 127.692 135.638 1.00 72.89  ?  199  ALA Q CB  1 
ATOM 1205 N N   . ILE A 1 224 ? 122.222 127.599 133.569 1.00 67.40  ?  200  ILE Q N   1 
ATOM 1206 C CA  . ILE A 1 224 ? 121.418 126.850 132.605 1.00 67.40  ?  200  ILE Q CA  1 
ATOM 1207 C C   . ILE A 1 224 ? 121.488 127.507 131.233 1.00 67.40  ?  200  ILE Q C   1 
ATOM 1208 O O   . ILE A 1 224 ? 121.661 126.831 130.204 1.00 67.40  ?  200  ILE Q O   1 
ATOM 1209 C CB  . ILE A 1 224 ? 119.965 126.720 133.096 1.00 67.40  ?  200  ILE Q CB  1 
ATOM 1210 C CG1 . ILE A 1 224 ? 119.912 126.044 134.466 1.00 67.40  ?  200  ILE Q CG1 1 
ATOM 1211 C CG2 . ILE A 1 224 ? 119.133 125.945 132.094 1.00 67.40  ?  200  ILE Q CG2 1 
ATOM 1212 C CD1 . ILE A 1 224 ? 120.832 124.853 134.610 1.00 67.40  ?  200  ILE Q CD1 1 
ATOM 1213 N N   . ALA A 1 225 ? 121.366 128.836 131.194 1.00 67.31  ?  201  ALA Q N   1 
ATOM 1214 C CA  . ALA A 1 225 ? 121.482 129.539 129.921 1.00 67.31  ?  201  ALA Q CA  1 
ATOM 1215 C C   . ALA A 1 225 ? 122.848 129.306 129.289 1.00 67.31  ?  201  ALA Q C   1 
ATOM 1216 O O   . ALA A 1 225 ? 122.958 129.118 128.066 1.00 67.31  ?  201  ALA Q O   1 
ATOM 1217 C CB  . ALA A 1 225 ? 121.228 131.032 130.120 1.00 67.31  ?  201  ALA Q CB  1 
ATOM 1218 N N   . PHE A 1 226 ? 123.903 129.313 130.107 1.00 63.82  ?  202  PHE Q N   1 
ATOM 1219 C CA  . PHE A 1 226 ? 125.243 129.099 129.571 1.00 63.82  ?  202  PHE Q CA  1 
ATOM 1220 C C   . PHE A 1 226 ? 125.377 127.718 128.946 1.00 63.82  ?  202  PHE Q C   1 
ATOM 1221 O O   . PHE A 1 226 ? 125.981 127.567 127.878 1.00 63.82  ?  202  PHE Q O   1 
ATOM 1222 C CB  . PHE A 1 226 ? 126.291 129.281 130.660 1.00 63.82  ?  202  PHE Q CB  1 
ATOM 1223 C CG  . PHE A 1 226 ? 127.604 128.640 130.334 1.00 63.82  ?  202  PHE Q CG  1 
ATOM 1224 C CD1 . PHE A 1 226 ? 128.446 129.211 129.404 1.00 63.82  ?  202  PHE Q CD1 1 
ATOM 1225 C CD2 . PHE A 1 226 ? 127.993 127.466 130.947 1.00 63.82  ?  202  PHE Q CD2 1 
ATOM 1226 C CE1 . PHE A 1 226 ? 129.650 128.635 129.097 1.00 63.82  ?  202  PHE Q CE1 1 
ATOM 1227 C CE2 . PHE A 1 226 ? 129.202 126.882 130.642 1.00 63.82  ?  202  PHE Q CE2 1 
ATOM 1228 C CZ  . PHE A 1 226 ? 130.030 127.469 129.713 1.00 63.82  ?  202  PHE Q CZ  1 
ATOM 1229 N N   . PHE A 1 227 ? 124.834 126.692 129.599 1.00 60.47  ?  203  PHE Q N   1 
ATOM 1230 C CA  . PHE A 1 227 ? 124.963 125.353 129.034 1.00 60.47  ?  203  PHE Q CA  1 
ATOM 1231 C C   . PHE A 1 227 ? 124.170 125.223 127.738 1.00 60.47  ?  203  PHE Q C   1 
ATOM 1232 O O   . PHE A 1 227 ? 124.626 124.578 126.781 1.00 60.47  ?  203  PHE Q O   1 
ATOM 1233 C CB  . PHE A 1 227 ? 124.535 124.308 130.055 1.00 60.47  ?  203  PHE Q CB  1 
ATOM 1234 C CG  . PHE A 1 227 ? 125.618 123.952 131.024 1.00 60.47  ?  203  PHE Q CG  1 
ATOM 1235 C CD1 . PHE A 1 227 ? 126.926 123.839 130.602 1.00 60.47  ?  203  PHE Q CD1 1 
ATOM 1236 C CD2 . PHE A 1 227 ? 125.333 123.747 132.359 1.00 60.47  ?  203  PHE Q CD2 1 
ATOM 1237 C CE1 . PHE A 1 227 ? 127.927 123.520 131.487 1.00 60.47  ?  203  PHE Q CE1 1 
ATOM 1238 C CE2 . PHE A 1 227 ? 126.332 123.427 133.248 1.00 60.47  ?  203  PHE Q CE2 1 
ATOM 1239 C CZ  . PHE A 1 227 ? 127.631 123.313 132.810 1.00 60.47  ?  203  PHE Q CZ  1 
ATOM 1240 N N   . MET A 1 228 ? 122.996 125.854 127.675 1.00 61.68  ?  204  MET Q N   1 
ATOM 1241 C CA  . MET A 1 228 ? 122.225 125.837 126.435 1.00 61.68  ?  204  MET Q CA  1 
ATOM 1242 C C   . MET A 1 228 ? 123.009 126.468 125.286 1.00 61.68  ?  204  MET Q C   1 
ATOM 1243 O O   . MET A 1 228 ? 123.102 125.898 124.184 1.00 61.68  ?  204  MET Q O   1 
ATOM 1244 C CB  . MET A 1 228 ? 120.900 126.567 126.642 1.00 61.68  ?  204  MET Q CB  1 
ATOM 1245 C CG  . MET A 1 228 ? 119.754 126.006 125.838 1.00 61.68  ?  204  MET Q CG  1 
ATOM 1246 S SD  . MET A 1 228 ? 118.942 124.673 126.726 1.00 61.68  ?  204  MET Q SD  1 
ATOM 1247 C CE  . MET A 1 228 ? 117.965 125.607 127.897 1.00 61.68  ?  204  MET Q CE  1 
ATOM 1248 N N   . VAL A 1 229 ? 123.581 127.654 125.521 1.00 60.81  ?  205  VAL Q N   1 
ATOM 1249 C CA  . VAL A 1 229 ? 124.295 128.327 124.438 1.00 60.81  ?  205  VAL Q CA  1 
ATOM 1250 C C   . VAL A 1 229 ? 125.547 127.547 124.060 1.00 60.81  ?  205  VAL Q C   1 
ATOM 1251 O O   . VAL A 1 229 ? 125.956 127.535 122.892 1.00 60.81  ?  205  VAL Q O   1 
ATOM 1252 C CB  . VAL A 1 229 ? 124.617 129.791 124.796 1.00 60.81  ?  205  VAL Q CB  1 
ATOM 1253 C CG1 . VAL A 1 229 ? 123.335 130.593 124.935 1.00 60.81  ?  205  VAL Q CG1 1 
ATOM 1254 C CG2 . VAL A 1 229 ? 125.457 129.889 126.043 1.00 60.81  ?  205  VAL Q CG2 1 
ATOM 1255 N N   . PHE A 1 230 ? 126.168 126.869 125.030 1.00 64.61  ?  206  PHE Q N   1 
ATOM 1256 C CA  . PHE A 1 230 ? 127.314 126.029 124.701 1.00 64.61  ?  206  PHE Q CA  1 
ATOM 1257 C C   . PHE A 1 230 ? 126.916 124.903 123.762 1.00 64.61  ?  206  PHE Q C   1 
ATOM 1258 O O   . PHE A 1 230 ? 127.637 124.602 122.802 1.00 64.61  ?  206  PHE Q O   1 
ATOM 1259 C CB  . PHE A 1 230 ? 127.940 125.457 125.967 1.00 64.61  ?  206  PHE Q CB  1 
ATOM 1260 C CG  . PHE A 1 230 ? 129.302 124.873 125.749 1.00 64.61  ?  206  PHE Q CG  1 
ATOM 1261 C CD1 . PHE A 1 230 ? 130.352 125.672 125.344 1.00 64.61  ?  206  PHE Q CD1 1 
ATOM 1262 C CD2 . PHE A 1 230 ? 129.530 123.527 125.936 1.00 64.61  ?  206  PHE Q CD2 1 
ATOM 1263 C CE1 . PHE A 1 230 ? 131.604 125.139 125.142 1.00 64.61  ?  206  PHE Q CE1 1 
ATOM 1264 C CE2 . PHE A 1 230 ? 130.779 122.990 125.737 1.00 64.61  ?  206  PHE Q CE2 1 
ATOM 1265 C CZ  . PHE A 1 230 ? 131.818 123.797 125.338 1.00 64.61  ?  206  PHE Q CZ  1 
ATOM 1266 N N   . GLY A 1 231 ? 125.775 124.265 124.022 1.00 60.59  ?  207  GLY Q N   1 
ATOM 1267 C CA  . GLY A 1 231 ? 125.320 123.216 123.121 1.00 60.59  ?  207  GLY Q CA  1 
ATOM 1268 C C   . GLY A 1 231 ? 125.076 123.728 121.712 1.00 60.59  ?  207  GLY Q C   1 
ATOM 1269 O O   . GLY A 1 231 ? 125.499 123.111 120.721 1.00 60.59  ?  207  GLY Q O   1 
ATOM 1270 N N   . ILE A 1 232 ? 124.393 124.869 121.604 1.00 58.28  ?  208  ILE Q N   1 
ATOM 1271 C CA  . ILE A 1 232 ? 124.128 125.432 120.281 1.00 58.28  ?  208  ILE Q CA  1 
ATOM 1272 C C   . ILE A 1 232 ? 125.437 125.734 119.559 1.00 58.28  ?  208  ILE Q C   1 
ATOM 1273 O O   . ILE A 1 232 ? 125.591 125.437 118.364 1.00 58.28  ?  208  ILE Q O   1 
ATOM 1274 C CB  . ILE A 1 232 ? 123.239 126.682 120.393 1.00 58.28  ?  208  ILE Q CB  1 
ATOM 1275 C CG1 . ILE A 1 232 ? 121.771 126.282 120.465 1.00 58.28  ?  208  ILE Q CG1 1 
ATOM 1276 C CG2 . ILE A 1 232 ? 123.457 127.605 119.216 1.00 58.28  ?  208  ILE Q CG2 1 
ATOM 1277 C CD1 . ILE A 1 232 ? 120.880 127.368 121.016 1.00 58.28  ?  208  ILE Q CD1 1 
ATOM 1278 N N   . MET A 1 233 ? 126.403 126.317 120.274 1.00 64.05  ?  209  MET Q N   1 
ATOM 1279 C CA  . MET A 1 233 ? 127.690 126.635 119.666 1.00 64.05  ?  209  MET Q CA  1 
ATOM 1280 C C   . MET A 1 233 ? 128.387 125.376 119.176 1.00 64.05  ?  209  MET Q C   1 
ATOM 1281 O O   . MET A 1 233 ? 128.981 125.366 118.090 1.00 64.05  ?  209  MET Q O   1 
ATOM 1282 C CB  . MET A 1 233 ? 128.575 127.364 120.675 1.00 64.05  ?  209  MET Q CB  1 
ATOM 1283 C CG  . MET A 1 233 ? 129.515 128.387 120.079 1.00 64.05  ?  209  MET Q CG  1 
ATOM 1284 S SD  . MET A 1 233 ? 128.737 130.003 119.968 1.00 64.05  ?  209  MET Q SD  1 
ATOM 1285 C CE  . MET A 1 233 ? 128.317 130.284 121.684 1.00 64.05  ?  209  MET Q CE  1 
ATOM 1286 N N   . LEU A 1 234 ? 128.334 124.307 119.971 1.00 58.54  ?  210  LEU Q N   1 
ATOM 1287 C CA  . LEU A 1 234 ? 128.988 123.062 119.590 1.00 58.54  ?  210  LEU Q CA  1 
ATOM 1288 C C   . LEU A 1 234 ? 128.419 122.516 118.291 1.00 58.54  ?  210  LEU Q C   1 
ATOM 1289 O O   . LEU A 1 234 ? 129.167 122.122 117.383 1.00 58.54  ?  210  LEU Q O   1 
ATOM 1290 C CB  . LEU A 1 234 ? 128.839 122.040 120.710 1.00 58.54  ?  210  LEU Q CB  1 
ATOM 1291 C CG  . LEU A 1 234 ? 129.656 120.764 120.576 1.00 58.54  ?  210  LEU Q CG  1 
ATOM 1292 C CD1 . LEU A 1 234 ? 131.043 120.952 121.135 1.00 58.54  ?  210  LEU Q CD1 1 
ATOM 1293 C CD2 . LEU A 1 234 ? 128.948 119.639 121.310 1.00 58.54  ?  210  LEU Q CD2 1 
ATOM 1294 N N   . GLN A 1 235 ? 127.091 122.482 118.185 1.00 57.45  ?  211  GLN Q N   1 
ATOM 1295 C CA  . GLN A 1 235 ? 126.492 121.933 116.973 1.00 57.45  ?  211  GLN Q CA  1 
ATOM 1296 C C   . GLN A 1 235 ? 126.816 122.817 115.776 1.00 57.45  ?  211  GLN Q C   1 
ATOM 1297 O O   . GLN A 1 235 ? 127.138 122.311 114.687 1.00 57.45  ?  211  GLN Q O   1 
ATOM 1298 C CB  . GLN A 1 235 ? 124.984 121.730 117.215 1.00 57.45  ?  211  GLN Q CB  1 
ATOM 1299 C CG  . GLN A 1 235 ? 124.118 120.936 116.195 1.00 57.45  ?  211  GLN Q CG  1 
ATOM 1300 C CD  . GLN A 1 235 ? 124.104 121.392 114.750 1.00 57.45  ?  211  GLN Q CD  1 
ATOM 1301 O OE1 . GLN A 1 235 ? 124.603 122.439 114.398 1.00 57.45  ?  211  GLN Q OE1 1 
ATOM 1302 N NE2 . GLN A 1 235 ? 123.546 120.557 113.893 1.00 57.45  ?  211  GLN Q NE2 1 
ATOM 1303 N N   . LEU A 1 236 ? 126.761 124.140 115.960 1.00 56.78  ?  212  LEU Q N   1 
ATOM 1304 C CA  . LEU A 1 236 ? 127.080 125.042 114.860 1.00 56.78  ?  212  LEU Q CA  1 
ATOM 1305 C C   . LEU A 1 236 ? 128.498 124.820 114.362 1.00 56.78  ?  212  LEU Q C   1 
ATOM 1306 O O   . LEU A 1 236 ? 128.744 124.798 113.148 1.00 56.78  ?  212  LEU Q O   1 
ATOM 1307 C CB  . LEU A 1 236 ? 126.892 126.493 115.285 1.00 56.78  ?  212  LEU Q CB  1 
ATOM 1308 C CG  . LEU A 1 236 ? 125.518 127.086 115.006 1.00 56.78  ?  212  LEU Q CG  1 
ATOM 1309 C CD1 . LEU A 1 236 ? 125.374 128.443 115.659 1.00 56.78  ?  212  LEU Q CD1 1 
ATOM 1310 C CD2 . LEU A 1 236 ? 125.302 127.193 113.510 1.00 56.78  ?  212  LEU Q CD2 1 
ATOM 1311 N N   . TYR A 1 237 ? 129.445 124.645 115.284 1.00 61.61  ?  213  TYR Q N   1 
ATOM 1312 C CA  . TYR A 1 237 ? 130.822 124.429 114.866 1.00 61.61  ?  213  TYR Q CA  1 
ATOM 1313 C C   . TYR A 1 237 ? 130.990 123.090 114.171 1.00 61.61  ?  213  TYR Q C   1 
ATOM 1314 O O   . TYR A 1 237 ? 131.785 122.981 113.231 1.00 61.61  ?  213  TYR Q O   1 
ATOM 1315 C CB  . TYR A 1 237 ? 131.770 124.533 116.052 1.00 61.61  ?  213  TYR Q CB  1 
ATOM 1316 C CG  . TYR A 1 237 ? 132.559 125.812 116.042 1.00 61.61  ?  213  TYR Q CG  1 
ATOM 1317 C CD1 . TYR A 1 237 ? 131.939 127.028 116.285 1.00 61.61  ?  213  TYR Q CD1 1 
ATOM 1318 C CD2 . TYR A 1 237 ? 133.906 125.815 115.743 1.00 61.61  ?  213  TYR Q CD2 1 
ATOM 1319 C CE1 . TYR A 1 237 ? 132.649 128.207 116.264 1.00 61.61  ?  213  TYR Q CE1 1 
ATOM 1320 C CE2 . TYR A 1 237 ? 134.624 126.989 115.714 1.00 61.61  ?  213  TYR Q CE2 1 
ATOM 1321 C CZ  . TYR A 1 237 ? 133.992 128.184 115.976 1.00 61.61  ?  213  TYR Q CZ  1 
ATOM 1322 O OH  . TYR A 1 237 ? 134.708 129.359 115.949 1.00 61.61  ?  213  TYR Q OH  1 
ATOM 1323 N N   . ALA A 1 238 ? 130.255 122.067 114.603 1.00 54.54  ?  214  ALA Q N   1 
ATOM 1324 C CA  . ALA A 1 238 ? 130.307 120.795 113.889 1.00 54.54  ?  214  ALA Q CA  1 
ATOM 1325 C C   . ALA A 1 238 ? 129.856 120.965 112.443 1.00 54.54  ?  214  ALA Q C   1 
ATOM 1326 O O   . ALA A 1 238 ? 130.496 120.455 111.513 1.00 54.54  ?  214  ALA Q O   1 
ATOM 1327 C CB  . ALA A 1 238 ? 129.452 119.752 114.605 1.00 54.54  ?  214  ALA Q CB  1 
ATOM 1328 N N   . GLN A 1 239 ? 128.759 121.697 112.232 1.00 51.54  ?  215  GLN Q N   1 
ATOM 1329 C CA  . GLN A 1 239 ? 128.275 121.914 110.869 1.00 51.54  ?  215  GLN Q CA  1 
ATOM 1330 C C   . GLN A 1 239 ? 129.287 122.687 110.035 1.00 51.54  ?  215  GLN Q C   1 
ATOM 1331 O O   . GLN A 1 239 ? 129.536 122.351 108.869 1.00 51.54  ?  215  GLN Q O   1 
ATOM 1332 C CB  . GLN A 1 239 ? 126.936 122.645 110.884 1.00 51.54  ?  215  GLN Q CB  1 
ATOM 1333 C CG  . GLN A 1 239 ? 125.797 121.817 111.421 1.00 51.54  ?  215  GLN Q CG  1 
ATOM 1334 C CD  . GLN A 1 239 ? 125.100 121.037 110.331 1.00 51.54  ?  215  GLN Q CD  1 
ATOM 1335 O OE1 . GLN A 1 239 ? 123.953 121.316 109.992 1.00 51.54  ?  215  GLN Q OE1 1 
ATOM 1336 N NE2 . GLN A 1 239 ? 125.794 120.054 109.769 1.00 51.54  ?  215  GLN Q NE2 1 
ATOM 1337 N N   . ILE A 1 240 ? 129.873 123.737 110.610 1.00 52.74  ?  216  ILE Q N   1 
ATOM 1338 C CA  . ILE A 1 240 ? 130.806 124.549 109.835 1.00 52.74  ?  216  ILE Q CA  1 
ATOM 1339 C C   . ILE A 1 240 ? 132.056 123.746 109.491 1.00 52.74  ?  216  ILE Q C   1 
ATOM 1340 O O   . ILE A 1 240 ? 132.605 123.874 108.389 1.00 52.74  ?  216  ILE Q O   1 
ATOM 1341 C CB  . ILE A 1 240 ? 131.134 125.860 110.575 1.00 52.74  ?  216  ILE Q CB  1 
ATOM 1342 C CG1 . ILE A 1 240 ? 131.569 126.934 109.586 1.00 52.74  ?  216  ILE Q CG1 1 
ATOM 1343 C CG2 . ILE A 1 240 ? 132.204 125.670 111.633 1.00 52.74  ?  216  ILE Q CG2 1 
ATOM 1344 C CD1 . ILE A 1 240 ? 131.651 128.312 110.196 1.00 52.74  ?  216  ILE Q CD1 1 
ATOM 1345 N N   . CYS A 1 241 ? 132.511 122.885 110.407 1.00 60.62  ?  217  CYS Q N   1 
ATOM 1346 C CA  . CYS A 1 241 ? 133.664 122.044 110.110 1.00 60.62  ?  217  CYS Q CA  1 
ATOM 1347 C C   . CYS A 1 241 ? 133.346 121.044 109.009 1.00 60.62  ?  217  CYS Q C   1 
ATOM 1348 O O   . CYS A 1 241 ? 134.165 120.827 108.107 1.00 60.62  ?  217  CYS Q O   1 
ATOM 1349 C CB  . CYS A 1 241 ? 134.131 121.321 111.370 1.00 60.62  ?  217  CYS Q CB  1 
ATOM 1350 S SG  . CYS A 1 241 ? 135.876 120.856 111.357 1.00 60.62  ?  217  CYS Q SG  1 
ATOM 1351 N N   . ARG A 1 242 ? 132.159 120.433 109.056 1.00 58.82  ?  218  ARG Q N   1 
ATOM 1352 C CA  . ARG A 1 242 ? 131.785 119.487 108.009 1.00 58.82  ?  218  ARG Q CA  1 
ATOM 1353 C C   . ARG A 1 242 ? 131.743 120.167 106.649 1.00 58.82  ?  218  ARG Q C   1 
ATOM 1354 O O   . ARG A 1 242 ? 132.245 119.627 105.657 1.00 58.82  ?  218  ARG Q O   1 
ATOM 1355 C CB  . ARG A 1 242 ? 130.435 118.848 108.324 1.00 58.82  ?  218  ARG Q CB  1 
ATOM 1356 C CG  . ARG A 1 242 ? 129.661 118.428 107.085 1.00 58.82  ?  218  ARG Q CG  1 
ATOM 1357 C CD  . ARG A 1 242 ? 128.763 117.243 107.360 1.00 58.82  ?  218  ARG Q CD  1 
ATOM 1358 N NE  . ARG A 1 242 ? 129.525 116.021 107.572 1.00 58.82  ?  218  ARG Q NE  1 
ATOM 1359 C CZ  . ARG A 1 242 ? 129.225 115.104 108.480 1.00 58.82  ?  218  ARG Q CZ  1 
ATOM 1360 N NH1 . ARG A 1 242 ? 128.181 115.240 109.280 1.00 58.82  1  218  ARG Q NH1 1 
ATOM 1361 N NH2 . ARG A 1 242 ? 129.992 114.022 108.587 1.00 58.82  ?  218  ARG Q NH2 1 
ATOM 1362 N N   . ILE A 1 243 ? 131.150 121.361 106.580 1.00 52.74  ?  219  ILE Q N   1 
ATOM 1363 C CA  . ILE A 1 243 ? 131.077 122.072 105.308 1.00 52.74  ?  219  ILE Q CA  1 
ATOM 1364 C C   . ILE A 1 243 ? 132.440 122.515 104.802 1.00 52.74  ?  219  ILE Q C   1 
ATOM 1365 O O   . ILE A 1 243 ? 132.713 122.389 103.603 1.00 52.74  ?  219  ILE Q O   1 
ATOM 1366 C CB  . ILE A 1 243 ? 130.127 123.282 105.417 1.00 52.74  ?  219  ILE Q CB  1 
ATOM 1367 C CG1 . ILE A 1 243 ? 128.695 122.858 105.103 1.00 52.74  ?  219  ILE Q CG1 1 
ATOM 1368 C CG2 . ILE A 1 243 ? 130.549 124.395 104.476 1.00 52.74  ?  219  ILE Q CG2 1 
ATOM 1369 C CD1 . ILE A 1 243 ? 128.421 122.687 103.627 1.00 52.74  ?  219  ILE Q CD1 1 
ATOM 1370 N N   . VAL A 1 244 ? 133.319 123.010 105.679 1.00 57.72  ?  220  VAL Q N   1 
ATOM 1371 C CA  . VAL A 1 244 ? 134.616 123.505 105.227 1.00 57.72  ?  220  VAL Q CA  1 
ATOM 1372 C C   . VAL A 1 244 ? 135.613 122.392 104.943 1.00 57.72  ?  220  VAL Q C   1 
ATOM 1373 O O   . VAL A 1 244 ? 136.595 122.627 104.222 1.00 57.72  ?  220  VAL Q O   1 
ATOM 1374 C CB  . VAL A 1 244 ? 135.219 124.485 106.253 1.00 57.72  ?  220  VAL Q CB  1 
ATOM 1375 C CG1 . VAL A 1 244 ? 135.861 123.732 107.406 1.00 57.72  ?  220  VAL Q CG1 1 
ATOM 1376 C CG2 . VAL A 1 244 ? 136.219 125.414 105.587 1.00 57.72  ?  220  VAL Q CG2 1 
ATOM 1377 N N   . CYS A 1 245 ? 135.403 121.188 105.480 1.00 66.86  ?  221  CYS Q N   1 
ATOM 1378 C CA  . CYS A 1 245 ? 136.306 120.082 105.174 1.00 66.86  ?  221  CYS Q CA  1 
ATOM 1379 C C   . CYS A 1 245 ? 136.206 119.682 103.709 1.00 66.86  ?  221  CYS Q C   1 
ATOM 1380 O O   . CYS A 1 245 ? 137.217 119.397 103.059 1.00 66.86  ?  221  CYS Q O   1 
ATOM 1381 C CB  . CYS A 1 245 ? 136.004 118.889 106.079 1.00 66.86  ?  221  CYS Q CB  1 
ATOM 1382 S SG  . CYS A 1 245 ? 137.468 117.952 106.567 1.00 66.86  ?  221  CYS Q SG  1 
ATOM 1383 N N   . ARG A 1 246 ? 134.985 119.649 103.174 1.00 73.38  ?  222  ARG Q N   1 
ATOM 1384 C CA  . ARG A 1 246 ? 134.781 119.294 101.774 1.00 73.38  ?  222  ARG Q CA  1 
ATOM 1385 C C   . ARG A 1 246 ? 135.560 120.207 100.842 1.00 73.38  ?  222  ARG Q C   1 
ATOM 1386 O O   . ARG A 1 246 ? 136.087 119.767 99.816  1.00 73.38  ?  222  ARG Q O   1 
ATOM 1387 C CB  . ARG A 1 246 ? 133.291 119.340 101.443 1.00 73.38  ?  222  ARG Q CB  1 
ATOM 1388 C CG  . ARG A 1 246 ? 132.968 119.012 99.992  1.00 73.38  ?  222  ARG Q CG  1 
ATOM 1389 C CD  . ARG A 1 246 ? 131.460 119.024 99.656  1.00 73.38  ?  222  ARG Q CD  1 
ATOM 1390 N NE  . ARG A 1 246 ? 130.495 118.624 100.683 1.00 73.38  ?  222  ARG Q NE  1 
ATOM 1391 C CZ  . ARG A 1 246 ? 130.615 117.620 101.549 1.00 73.38  ?  222  ARG Q CZ  1 
ATOM 1392 N NH1 . ARG A 1 246 ? 131.613 116.752 101.482 1.00 73.38  1  222  ARG Q NH1 1 
ATOM 1393 N NH2 . ARG A 1 246 ? 129.678 117.452 102.477 1.00 73.38  ?  222  ARG Q NH2 1 
ATOM 1394 N N   . HIS A 1 247 ? 135.647 121.488 101.185 1.00 82.71  ?  223  HIS Q N   1 
ATOM 1395 C CA  . HIS A 1 247 ? 136.435 122.421 100.394 1.00 82.71  ?  223  HIS Q CA  1 
ATOM 1396 C C   . HIS A 1 247 ? 137.864 122.372 100.927 1.00 82.71  ?  223  HIS Q C   1 
ATOM 1397 O O   . HIS A 1 247 ? 138.470 123.403 101.233 1.00 82.71  ?  223  HIS Q O   1 
ATOM 1398 C CB  . HIS A 1 247 ? 135.809 123.819 100.493 1.00 82.71  ?  223  HIS Q CB  1 
ATOM 1399 C CG  . HIS A 1 247 ? 136.553 124.899 99.771  1.00 82.71  ?  223  HIS Q CG  1 
ATOM 1400 N ND1 . HIS A 1 247 ? 136.086 126.194 99.710  1.00 82.71  ?  223  HIS Q ND1 1 
ATOM 1401 C CD2 . HIS A 1 247 ? 137.690 124.877 99.035  1.00 82.71  ?  223  HIS Q CD2 1 
ATOM 1402 C CE1 . HIS A 1 247 ? 136.926 126.932 99.006  1.00 82.71  ?  223  HIS Q CE1 1 
ATOM 1403 N NE2 . HIS A 1 247 ? 137.908 126.156 98.585  1.00 82.71  ?  223  HIS Q NE2 1 
ATOM 1404 N N   . ALA A 1 248 ? 138.388 121.163 101.109 1.00 88.71  ?  224  ALA Q N   1 
ATOM 1405 C CA  . ALA A 1 248 ? 139.813 120.955 101.322 1.00 88.71  ?  224  ALA Q CA  1 
ATOM 1406 C C   . ALA A 1 248 ? 140.250 119.711 100.568 1.00 88.71  ?  224  ALA Q C   1 
ATOM 1407 O O   . ALA A 1 248 ? 141.421 119.566 100.207 1.00 88.71  ?  224  ALA Q O   1 
ATOM 1408 C CB  . ALA A 1 248 ? 140.133 120.831 102.812 1.00 88.71  ?  224  ALA Q CB  1 
ATOM 1409 N N   . ALA A 1 265 ? 146.995 119.056 106.420 1.00 146.83 ?  241  ALA Q N   1 
ATOM 1410 C CA  . ALA A 1 265 ? 145.890 118.228 105.952 1.00 146.83 ?  241  ALA Q CA  1 
ATOM 1411 C C   . ALA A 1 265 ? 144.892 117.969 107.075 1.00 146.83 ?  241  ALA Q C   1 
ATOM 1412 O O   . ALA A 1 265 ? 144.131 118.858 107.457 1.00 146.83 ?  241  ALA Q O   1 
ATOM 1413 C CB  . ALA A 1 265 ? 146.411 116.915 105.390 1.00 146.83 ?  241  ALA Q CB  1 
ATOM 1414 N N   . THR A 1 266 ? 144.898 116.740 107.595 1.00 149.31 ?  242  THR Q N   1 
ATOM 1415 C CA  . THR A 1 266 ? 144.002 116.394 108.693 1.00 149.31 ?  242  THR Q CA  1 
ATOM 1416 C C   . THR A 1 266 ? 144.315 117.221 109.934 1.00 149.31 ?  242  THR Q C   1 
ATOM 1417 O O   . THR A 1 266 ? 143.411 117.775 110.571 1.00 149.31 ?  242  THR Q O   1 
ATOM 1418 C CB  . THR A 1 266 ? 144.102 114.899 109.001 1.00 149.31 ?  242  THR Q CB  1 
ATOM 1419 O OG1 . THR A 1 266 ? 143.472 114.150 107.955 1.00 149.31 ?  242  THR Q OG1 1 
ATOM 1420 C CG2 . THR A 1 266 ? 143.427 114.576 110.327 1.00 149.31 ?  242  THR Q CG2 1 
ATOM 1421 N N   . ARG A 1 267 ? 145.598 117.322 110.288 1.00 148.72 ?  243  ARG Q N   1 
ATOM 1422 C CA  . ARG A 1 267 ? 145.978 118.107 111.459 1.00 148.72 ?  243  ARG Q CA  1 
ATOM 1423 C C   . ARG A 1 267 ? 145.640 119.582 111.266 1.00 148.72 ?  243  ARG Q C   1 
ATOM 1424 O O   . ARG A 1 267 ? 145.100 120.224 112.175 1.00 148.72 ?  243  ARG Q O   1 
ATOM 1425 C CB  . ARG A 1 267 ? 147.467 117.915 111.769 1.00 148.72 ?  243  ARG Q CB  1 
ATOM 1426 C CG  . ARG A 1 267 ? 148.439 118.438 110.714 1.00 148.72 ?  243  ARG Q CG  1 
ATOM 1427 C CD  . ARG A 1 267 ? 148.742 117.394 109.650 1.00 148.72 ?  243  ARG Q CD  1 
ATOM 1428 N NE  . ARG A 1 267 ? 149.357 117.987 108.468 1.00 148.72 ?  243  ARG Q NE  1 
ATOM 1429 C CZ  . ARG A 1 267 ? 149.788 117.297 107.421 1.00 148.72 ?  243  ARG Q CZ  1 
ATOM 1430 N NH1 . ARG A 1 267 ? 149.688 115.979 107.373 1.00 148.72 1  243  ARG Q NH1 1 
ATOM 1431 N NH2 . ARG A 1 267 ? 150.333 117.946 106.396 1.00 148.72 ?  243  ARG Q NH2 1 
ATOM 1432 N N   . LYS A 1 268 ? 145.927 120.131 110.082 1.00 146.12 ?  244  LYS Q N   1 
ATOM 1433 C CA  . LYS A 1 268 ? 145.593 121.526 109.814 1.00 146.12 ?  244  LYS Q CA  1 
ATOM 1434 C C   . LYS A 1 268 ? 144.084 121.730 109.769 1.00 146.12 ?  244  LYS Q C   1 
ATOM 1435 O O   . LYS A 1 268 ? 143.573 122.733 110.280 1.00 146.12 ?  244  LYS Q O   1 
ATOM 1436 C CB  . LYS A 1 268 ? 146.237 121.982 108.506 1.00 146.12 ?  244  LYS Q CB  1 
ATOM 1437 C CG  . LYS A 1 268 ? 145.933 123.427 108.141 1.00 146.12 ?  244  LYS Q CG  1 
ATOM 1438 C CD  . LYS A 1 268 ? 146.570 123.811 106.816 1.00 146.12 ?  244  LYS Q CD  1 
ATOM 1439 C CE  . LYS A 1 268 ? 146.217 125.238 106.428 1.00 146.12 ?  244  LYS Q CE  1 
ATOM 1440 N NZ  . LYS A 1 268 ? 144.746 125.432 106.302 1.00 146.12 1  244  LYS Q NZ  1 
ATOM 1441 N N   . GLY A 1 269 ? 143.356 120.789 109.165 1.00 143.10 ?  245  GLY Q N   1 
ATOM 1442 C CA  . GLY A 1 269 ? 141.908 120.902 109.124 1.00 143.10 ?  245  GLY Q CA  1 
ATOM 1443 C C   . GLY A 1 269 ? 141.283 120.902 110.506 1.00 143.10 ?  245  GLY Q C   1 
ATOM 1444 O O   . GLY A 1 269 ? 140.362 121.675 110.781 1.00 143.10 ?  245  GLY Q O   1 
ATOM 1445 N N   . ILE A 1 270 ? 141.771 120.033 111.392 1.00 137.67 ?  246  ILE Q N   1 
ATOM 1446 C CA  . ILE A 1 270 ? 141.269 120.013 112.762 1.00 137.67 ?  246  ILE Q CA  1 
ATOM 1447 C C   . ILE A 1 270 ? 141.650 121.298 113.487 1.00 137.67 ?  246  ILE Q C   1 
ATOM 1448 O O   . ILE A 1 270 ? 140.806 121.948 114.114 1.00 137.67 ?  246  ILE Q O   1 
ATOM 1449 C CB  . ILE A 1 270 ? 141.784 118.769 113.508 1.00 137.67 ?  246  ILE Q CB  1 
ATOM 1450 C CG1 . ILE A 1 270 ? 141.194 117.497 112.896 1.00 137.67 ?  246  ILE Q CG1 1 
ATOM 1451 C CG2 . ILE A 1 270 ? 141.447 118.858 114.989 1.00 137.67 ?  246  ILE Q CG2 1 
ATOM 1452 C CD1 . ILE A 1 270 ? 141.647 116.225 113.578 1.00 137.67 ?  246  ILE Q CD1 1 
ATOM 1453 N N   . ALA A 1 271 ? 142.922 121.698 113.395 1.00 130.81 ?  247  ALA Q N   1 
ATOM 1454 C CA  . ALA A 1 271 ? 143.386 122.886 114.100 1.00 130.81 ?  247  ALA Q CA  1 
ATOM 1455 C C   . ALA A 1 271 ? 142.744 124.162 113.577 1.00 130.81 ?  247  ALA Q C   1 
ATOM 1456 O O   . ALA A 1 271 ? 142.795 125.188 114.263 1.00 130.81 ?  247  ALA Q O   1 
ATOM 1457 C CB  . ALA A 1 271 ? 144.907 122.996 114.002 1.00 130.81 ?  247  ALA Q CB  1 
ATOM 1458 N N   . THR A 1 272 ? 142.159 124.125 112.379 1.00 125.94 ?  248  THR Q N   1 
ATOM 1459 C CA  . THR A 1 272 ? 141.454 125.296 111.868 1.00 125.94 ?  248  THR Q CA  1 
ATOM 1460 C C   . THR A 1 272 ? 140.368 125.737 112.837 1.00 125.94 ?  248  THR Q C   1 
ATOM 1461 O O   . THR A 1 272 ? 140.266 126.921 113.179 1.00 125.94 ?  248  THR Q O   1 
ATOM 1462 C CB  . THR A 1 272 ? 140.859 124.993 110.492 1.00 125.94 ?  248  THR Q CB  1 
ATOM 1463 O OG1 . THR A 1 272 ? 141.879 124.468 109.633 1.00 125.94 ?  248  THR Q OG1 1 
ATOM 1464 C CG2 . THR A 1 272 ? 140.282 126.257 109.872 1.00 125.94 ?  248  THR Q CG2 1 
ATOM 1465 N N   . LEU A 1 273 ? 139.544 124.793 113.298 1.00 107.01 ?  249  LEU Q N   1 
ATOM 1466 C CA  . LEU A 1 273 ? 138.583 125.054 114.368 1.00 107.01 ?  249  LEU Q CA  1 
ATOM 1467 C C   . LEU A 1 273 ? 138.747 123.947 115.408 1.00 107.01 ?  249  LEU Q C   1 
ATOM 1468 O O   . LEU A 1 273 ? 137.968 122.993 115.456 1.00 107.01 ?  249  LEU Q O   1 
ATOM 1469 C CB  . LEU A 1 273 ? 137.154 125.122 113.817 1.00 107.01 ?  249  LEU Q CB  1 
ATOM 1470 C CG  . LEU A 1 273 ? 136.952 125.835 112.473 1.00 107.01 ?  249  LEU Q CG  1 
ATOM 1471 C CD1 . LEU A 1 273 ? 137.046 124.856 111.306 1.00 107.01 ?  249  LEU Q CD1 1 
ATOM 1472 C CD2 . LEU A 1 273 ? 135.632 126.584 112.433 1.00 107.01 ?  249  LEU Q CD2 1 
ATOM 1473 N N   . ALA A 1 274 ? 139.771 124.089 116.246 1.00 105.01 ?  250  ALA Q N   1 
ATOM 1474 C CA  . ALA A 1 274 ? 139.913 123.296 117.464 1.00 105.01 ?  250  ALA Q CA  1 
ATOM 1475 C C   . ALA A 1 274 ? 140.414 124.099 118.648 1.00 105.01 ?  250  ALA Q C   1 
ATOM 1476 O O   . ALA A 1 274 ? 140.171 123.692 119.789 1.00 105.01 ?  250  ALA Q O   1 
ATOM 1477 C CB  . ALA A 1 274 ? 140.858 122.111 117.238 1.00 105.01 ?  250  ALA Q CB  1 
ATOM 1478 N N   . VAL A 1 275 ? 141.102 125.217 118.428 1.00 98.87  ?  251  VAL Q N   1 
ATOM 1479 C CA  . VAL A 1 275 ? 141.623 126.002 119.535 1.00 98.87  ?  251  VAL Q CA  1 
ATOM 1480 C C   . VAL A 1 275 ? 140.562 126.957 120.064 1.00 98.87  ?  251  VAL Q C   1 
ATOM 1481 O O   . VAL A 1 275 ? 140.529 127.248 121.263 1.00 98.87  ?  251  VAL Q O   1 
ATOM 1482 C CB  . VAL A 1 275 ? 142.896 126.745 119.091 1.00 98.87  ?  251  VAL Q CB  1 
ATOM 1483 C CG1 . VAL A 1 275 ? 143.287 127.822 120.094 1.00 98.87  ?  251  VAL Q CG1 1 
ATOM 1484 C CG2 . VAL A 1 275 ? 144.037 125.761 118.891 1.00 98.87  ?  251  VAL Q CG2 1 
ATOM 1485 N N   . VAL A 1 276 ? 139.666 127.439 119.200 1.00 90.80  ?  252  VAL Q N   1 
ATOM 1486 C CA  . VAL A 1 276 ? 138.684 128.431 119.631 1.00 90.80  ?  252  VAL Q CA  1 
ATOM 1487 C C   . VAL A 1 276 ? 137.671 127.806 120.590 1.00 90.80  ?  252  VAL Q C   1 
ATOM 1488 O O   . VAL A 1 276 ? 137.386 128.355 121.664 1.00 90.80  ?  252  VAL Q O   1 
ATOM 1489 C CB  . VAL A 1 276 ? 138.019 129.091 118.407 1.00 90.80  ?  252  VAL Q CB  1 
ATOM 1490 C CG1 . VAL A 1 276 ? 139.075 129.460 117.384 1.00 90.80  ?  252  VAL Q CG1 1 
ATOM 1491 C CG2 . VAL A 1 276 ? 137.013 128.183 117.755 1.00 90.80  ?  252  VAL Q CG2 1 
ATOM 1492 N N   . LEU A 1 277 ? 137.145 126.627 120.244 1.00 90.73  ?  253  LEU Q N   1 
ATOM 1493 C CA  . LEU A 1 277 ? 136.166 125.977 121.108 1.00 90.73  ?  253  LEU Q CA  1 
ATOM 1494 C C   . LEU A 1 277 ? 136.813 125.483 122.393 1.00 90.73  ?  253  LEU Q C   1 
ATOM 1495 O O   . LEU A 1 277 ? 136.227 125.597 123.477 1.00 90.73  ?  253  LEU Q O   1 
ATOM 1496 C CB  . LEU A 1 277 ? 135.492 124.824 120.368 1.00 90.73  ?  253  LEU Q CB  1 
ATOM 1497 C CG  . LEU A 1 277 ? 134.124 124.392 120.893 1.00 90.73  ?  253  LEU Q CG  1 
ATOM 1498 C CD1 . LEU A 1 277 ? 133.277 125.600 121.247 1.00 90.73  ?  253  LEU Q CD1 1 
ATOM 1499 C CD2 . LEU A 1 277 ? 133.417 123.530 119.868 1.00 90.73  ?  253  LEU Q CD2 1 
ATOM 1500 N N   . GLY A 1 278 ? 138.020 124.928 122.288 1.00 94.62  ?  254  GLY Q N   1 
ATOM 1501 C CA  . GLY A 1 278 ? 138.731 124.506 123.479 1.00 94.62  ?  254  GLY Q CA  1 
ATOM 1502 C C   . GLY A 1 278 ? 139.018 125.660 124.418 1.00 94.62  ?  254  GLY Q C   1 
ATOM 1503 O O   . GLY A 1 278 ? 138.876 125.532 125.634 1.00 94.62  ?  254  GLY Q O   1 
ATOM 1504 N N   . ALA A 1 279 ? 139.428 126.804 123.865 1.00 91.15  ?  255  ALA Q N   1 
ATOM 1505 C CA  . ALA A 1 279 ? 139.688 127.973 124.695 1.00 91.15  ?  255  ALA Q CA  1 
ATOM 1506 C C   . ALA A 1 279 ? 138.413 128.459 125.365 1.00 91.15  ?  255  ALA Q C   1 
ATOM 1507 O O   . ALA A 1 279 ? 138.407 128.749 126.567 1.00 91.15  ?  255  ALA Q O   1 
ATOM 1508 C CB  . ALA A 1 279 ? 140.311 129.086 123.854 1.00 91.15  ?  255  ALA Q CB  1 
ATOM 1509 N N   . PHE A 1 280 ? 137.317 128.526 124.607 1.00 81.23  ?  256  PHE Q N   1 
ATOM 1510 C CA  . PHE A 1 280 ? 136.039 128.936 125.178 1.00 81.23  ?  256  PHE Q CA  1 
ATOM 1511 C C   . PHE A 1 280 ? 135.638 128.033 126.340 1.00 81.23  ?  256  PHE Q C   1 
ATOM 1512 O O   . PHE A 1 280 ? 135.285 128.512 127.427 1.00 81.23  ?  256  PHE Q O   1 
ATOM 1513 C CB  . PHE A 1 280 ? 134.974 128.918 124.086 1.00 81.23  ?  256  PHE Q CB  1 
ATOM 1514 C CG  . PHE A 1 280 ? 133.633 129.389 124.536 1.00 81.23  ?  256  PHE Q CG  1 
ATOM 1515 C CD1 . PHE A 1 280 ? 133.476 130.642 125.080 1.00 81.23  ?  256  PHE Q CD1 1 
ATOM 1516 C CD2 . PHE A 1 280 ? 132.524 128.581 124.393 1.00 81.23  ?  256  PHE Q CD2 1 
ATOM 1517 C CE1 . PHE A 1 280 ? 132.243 131.073 125.484 1.00 81.23  ?  256  PHE Q CE1 1 
ATOM 1518 C CE2 . PHE A 1 280 ? 131.287 129.009 124.794 1.00 81.23  ?  256  PHE Q CE2 1 
ATOM 1519 C CZ  . PHE A 1 280 ? 131.145 130.255 125.341 1.00 81.23  ?  256  PHE Q CZ  1 
ATOM 1520 N N   . ALA A 1 281 ? 135.702 126.717 126.129 1.00 86.13  ?  257  ALA Q N   1 
ATOM 1521 C CA  . ALA A 1 281 ? 135.306 125.780 127.174 1.00 86.13  ?  257  ALA Q CA  1 
ATOM 1522 C C   . ALA A 1 281 ? 136.225 125.885 128.383 1.00 86.13  ?  257  ALA Q C   1 
ATOM 1523 O O   . ALA A 1 281 ? 135.763 126.070 129.515 1.00 86.13  ?  257  ALA Q O   1 
ATOM 1524 C CB  . ALA A 1 281 ? 135.299 124.355 126.623 1.00 86.13  ?  257  ALA Q CB  1 
ATOM 1525 N N   . ALA A 1 282 ? 137.537 125.792 128.163 1.00 90.55  ?  258  ALA Q N   1 
ATOM 1526 C CA  . ALA A 1 282 ? 138.484 125.812 129.268 1.00 90.55  ?  258  ALA Q CA  1 
ATOM 1527 C C   . ALA A 1 282 ? 138.500 127.147 129.992 1.00 90.55  ?  258  ALA Q C   1 
ATOM 1528 O O   . ALA A 1 282 ? 139.024 127.225 131.109 1.00 90.55  ?  258  ALA Q O   1 
ATOM 1529 C CB  . ALA A 1 282 ? 139.889 125.475 128.766 1.00 90.55  ?  258  ALA Q CB  1 
ATOM 1530 N N   . CYS A 1 283 ? 137.945 128.196 129.392 1.00 89.84  ?  259  CYS Q N   1 
ATOM 1531 C CA  . CYS A 1 283 ? 137.880 129.483 130.061 1.00 89.84  ?  259  CYS Q CA  1 
ATOM 1532 C C   . CYS A 1 283 ? 136.568 129.726 130.787 1.00 89.84  ?  259  CYS Q C   1 
ATOM 1533 O O   . CYS A 1 283 ? 136.556 130.465 131.775 1.00 89.84  ?  259  CYS Q O   1 
ATOM 1534 C CB  . CYS A 1 283 ? 138.112 130.611 129.053 1.00 89.84  ?  259  CYS Q CB  1 
ATOM 1535 S SG  . CYS A 1 283 ? 139.843 130.870 128.609 1.00 89.84  ?  259  CYS Q SG  1 
ATOM 1536 N N   . TRP A 1 284 ? 135.457 129.137 130.338 1.00 83.03  ?  260  TRP Q N   1 
ATOM 1537 C CA  . TRP A 1 284 ? 134.181 129.458 130.963 1.00 83.03  ?  260  TRP Q CA  1 
ATOM 1538 C C   . TRP A 1 284 ? 133.549 128.326 131.761 1.00 83.03  ?  260  TRP Q C   1 
ATOM 1539 O O   . TRP A 1 284 ? 132.652 128.597 132.563 1.00 83.03  ?  260  TRP Q O   1 
ATOM 1540 C CB  . TRP A 1 284 ? 133.175 129.937 129.909 1.00 83.03  ?  260  TRP Q CB  1 
ATOM 1541 C CG  . TRP A 1 284 ? 133.069 131.428 129.843 1.00 83.03  ?  260  TRP Q CG  1 
ATOM 1542 C CD1 . TRP A 1 284 ? 133.329 132.218 128.765 1.00 83.03  ?  260  TRP Q CD1 1 
ATOM 1543 C CD2 . TRP A 1 284 ? 132.679 132.309 130.900 1.00 83.03  ?  260  TRP Q CD2 1 
ATOM 1544 N NE1 . TRP A 1 284 ? 133.123 133.535 129.084 1.00 83.03  ?  260  TRP Q NE1 1 
ATOM 1545 C CE2 . TRP A 1 284 ? 132.723 133.617 130.390 1.00 83.03  ?  260  TRP Q CE2 1 
ATOM 1546 C CE3 . TRP A 1 284 ? 132.295 132.117 132.229 1.00 83.03  ?  260  TRP Q CE3 1 
ATOM 1547 C CZ2 . TRP A 1 284 ? 132.399 134.729 131.160 1.00 83.03  ?  260  TRP Q CZ2 1 
ATOM 1548 C CZ3 . TRP A 1 284 ? 131.973 133.221 132.992 1.00 83.03  ?  260  TRP Q CZ3 1 
ATOM 1549 C CH2 . TRP A 1 284 ? 132.027 134.511 132.456 1.00 83.03  ?  260  TRP Q CH2 1 
ATOM 1550 N N   . LEU A 1 285 ? 133.975 127.079 131.570 1.00 78.47  ?  261  LEU Q N   1 
ATOM 1551 C CA  . LEU A 1 285 ? 133.371 125.969 132.306 1.00 78.47  ?  261  LEU Q CA  1 
ATOM 1552 C C   . LEU A 1 285 ? 133.564 126.047 133.818 1.00 78.47  ?  261  LEU Q C   1 
ATOM 1553 O O   . LEU A 1 285 ? 132.580 125.833 134.552 1.00 78.47  ?  261  LEU Q O   1 
ATOM 1554 C CB  . LEU A 1 285 ? 133.907 124.646 131.752 1.00 78.47  ?  261  LEU Q CB  1 
ATOM 1555 C CG  . LEU A 1 285 ? 133.041 123.946 130.707 1.00 78.47  ?  261  LEU Q CG  1 
ATOM 1556 C CD1 . LEU A 1 285 ? 133.703 122.662 130.240 1.00 78.47  ?  261  LEU Q CD1 1 
ATOM 1557 C CD2 . LEU A 1 285 ? 131.664 123.663 131.267 1.00 78.47  ?  261  LEU Q CD2 1 
ATOM 1558 N N   . PRO A 1 286 ? 134.767 126.319 134.352 1.00 78.83  ?  262  PRO Q N   1 
ATOM 1559 C CA  . PRO A 1 286 ? 134.967 126.153 135.803 1.00 78.83  ?  262  PRO Q CA  1 
ATOM 1560 C C   . PRO A 1 286 ? 134.039 126.985 136.667 1.00 78.83  ?  262  PRO Q C   1 
ATOM 1561 O O   . PRO A 1 286 ? 133.565 126.491 137.699 1.00 78.83  ?  262  PRO Q O   1 
ATOM 1562 C CB  . PRO A 1 286 ? 136.431 126.565 135.996 1.00 78.83  ?  262  PRO Q CB  1 
ATOM 1563 C CG  . PRO A 1 286 ? 137.058 126.337 134.686 1.00 78.83  ?  262  PRO Q CG  1 
ATOM 1564 C CD  . PRO A 1 286 ? 136.020 126.719 133.691 1.00 78.83  ?  262  PRO Q CD  1 
ATOM 1565 N N   . PHE A 1 287 ? 133.756 128.229 136.280 1.00 81.18  ?  263  PHE Q N   1 
ATOM 1566 C CA  . PHE A 1 287 ? 132.902 129.069 137.113 1.00 81.18  ?  263  PHE Q CA  1 
ATOM 1567 C C   . PHE A 1 287 ? 131.493 128.501 137.210 1.00 81.18  ?  263  PHE Q C   1 
ATOM 1568 O O   . PHE A 1 287 ? 130.910 128.456 138.297 1.00 81.18  ?  263  PHE Q O   1 
ATOM 1569 C CB  . PHE A 1 287 ? 132.864 130.495 136.574 1.00 81.18  ?  263  PHE Q CB  1 
ATOM 1570 C CG  . PHE A 1 287 ? 131.814 131.350 137.217 1.00 81.18  ?  263  PHE Q CG  1 
ATOM 1571 C CD1 . PHE A 1 287 ? 131.776 131.505 138.590 1.00 81.18  ?  263  PHE Q CD1 1 
ATOM 1572 C CD2 . PHE A 1 287 ? 130.861 131.994 136.450 1.00 81.18  ?  263  PHE Q CD2 1 
ATOM 1573 C CE1 . PHE A 1 287 ? 130.811 132.286 139.186 1.00 81.18  ?  263  PHE Q CE1 1 
ATOM 1574 C CE2 . PHE A 1 287 ? 129.892 132.780 137.040 1.00 81.18  ?  263  PHE Q CE2 1 
ATOM 1575 C CZ  . PHE A 1 287 ? 129.868 132.925 138.411 1.00 81.18  ?  263  PHE Q CZ  1 
ATOM 1576 N N   . THR A 1 288 ? 130.930 128.054 136.086 1.00 76.02  ?  264  THR Q N   1 
ATOM 1577 C CA  . THR A 1 288 ? 129.577 127.510 136.114 1.00 76.02  ?  264  THR Q CA  1 
ATOM 1578 C C   . THR A 1 288 ? 129.528 126.174 136.847 1.00 76.02  ?  264  THR Q C   1 
ATOM 1579 O O   . THR A 1 288 ? 128.560 125.887 137.569 1.00 76.02  ?  264  THR Q O   1 
ATOM 1580 C CB  . THR A 1 288 ? 129.045 127.368 134.694 1.00 76.02  ?  264  THR Q CB  1 
ATOM 1581 O OG1 . THR A 1 288 ? 129.907 126.503 133.949 1.00 76.02  ?  264  THR Q OG1 1 
ATOM 1582 C CG2 . THR A 1 288 ? 129.000 128.725 134.025 1.00 76.02  ?  264  THR Q CG2 1 
ATOM 1583 N N   . VAL A 1 289 ? 130.560 125.345 136.683 1.00 75.61  ?  265  VAL Q N   1 
ATOM 1584 C CA  . VAL A 1 289 ? 130.596 124.083 137.415 1.00 75.61  ?  265  VAL Q CA  1 
ATOM 1585 C C   . VAL A 1 289 ? 130.642 124.344 138.915 1.00 75.61  ?  265  VAL Q C   1 
ATOM 1586 O O   . VAL A 1 289 ? 129.930 123.699 139.697 1.00 75.61  ?  265  VAL Q O   1 
ATOM 1587 C CB  . VAL A 1 289 ? 131.782 123.223 136.943 1.00 75.61  ?  265  VAL Q CB  1 
ATOM 1588 C CG1 . VAL A 1 289 ? 132.266 122.308 138.058 1.00 75.61  ?  265  VAL Q CG1 1 
ATOM 1589 C CG2 . VAL A 1 289 ? 131.387 122.414 135.721 1.00 75.61  ?  265  VAL Q CG2 1 
ATOM 1590 N N   . TYR A 1 290 ? 131.470 125.303 139.341 1.00 80.34  ?  266  TYR Q N   1 
ATOM 1591 C CA  . TYR A 1 290 ? 131.494 125.692 140.747 1.00 80.34  ?  266  TYR Q CA  1 
ATOM 1592 C C   . TYR A 1 290 ? 130.134 126.206 141.191 1.00 80.34  ?  266  TYR Q C   1 
ATOM 1593 O O   . TYR A 1 290 ? 129.650 125.855 142.273 1.00 80.34  ?  266  TYR Q O   1 
ATOM 1594 C CB  . TYR A 1 290 ? 132.559 126.763 140.970 1.00 80.34  ?  266  TYR Q CB  1 
ATOM 1595 C CG  . TYR A 1 290 ? 132.981 126.969 142.407 1.00 80.34  ?  266  TYR Q CG  1 
ATOM 1596 C CD1 . TYR A 1 290 ? 132.350 126.307 143.447 1.00 80.34  ?  266  TYR Q CD1 1 
ATOM 1597 C CD2 . TYR A 1 290 ? 133.986 127.866 142.723 1.00 80.34  ?  266  TYR Q CD2 1 
ATOM 1598 C CE1 . TYR A 1 290 ? 132.728 126.510 144.752 1.00 80.34  ?  266  TYR Q CE1 1 
ATOM 1599 C CE2 . TYR A 1 290 ? 134.367 128.079 144.024 1.00 80.34  ?  266  TYR Q CE2 1 
ATOM 1600 C CZ  . TYR A 1 290 ? 133.737 127.397 145.036 1.00 80.34  ?  266  TYR Q CZ  1 
ATOM 1601 O OH  . TYR A 1 290 ? 134.115 127.604 146.342 1.00 80.34  ?  266  TYR Q OH  1 
ATOM 1602 N N   . CYS A 1 291 ? 129.505 127.041 140.366 1.00 81.05  ?  267  CYS Q N   1 
ATOM 1603 C CA  . CYS A 1 291 ? 128.192 127.576 140.695 1.00 81.05  ?  267  CYS Q CA  1 
ATOM 1604 C C   . CYS A 1 291 ? 127.201 126.465 140.995 1.00 81.05  ?  267  CYS Q C   1 
ATOM 1605 O O   . CYS A 1 291 ? 126.426 126.553 141.954 1.00 81.05  ?  267  CYS Q O   1 
ATOM 1606 C CB  . CYS A 1 291 ? 127.690 128.438 139.543 1.00 81.05  ?  267  CYS Q CB  1 
ATOM 1607 S SG  . CYS A 1 291 ? 126.152 129.276 139.879 1.00 81.05  ?  267  CYS Q SG  1 
ATOM 1608 N N   . LEU A 1 292 ? 127.205 125.412 140.182 1.00 79.61  ?  268  LEU Q N   1 
ATOM 1609 C CA  . LEU A 1 292 ? 126.308 124.293 140.454 1.00 79.61  ?  268  LEU Q CA  1 
ATOM 1610 C C   . LEU A 1 292 ? 126.718 123.535 141.713 1.00 79.61  ?  268  LEU Q C   1 
ATOM 1611 O O   . LEU A 1 292 ? 125.879 123.270 142.580 1.00 79.61  ?  268  LEU Q O   1 
ATOM 1612 C CB  . LEU A 1 292 ? 126.252 123.351 139.254 1.00 79.61  ?  268  LEU Q CB  1 
ATOM 1613 C CG  . LEU A 1 292 ? 125.126 123.578 138.244 1.00 79.61  ?  268  LEU Q CG  1 
ATOM 1614 C CD1 . LEU A 1 292 ? 124.910 125.050 137.976 1.00 79.61  ?  268  LEU Q CD1 1 
ATOM 1615 C CD2 . LEU A 1 292 ? 125.421 122.835 136.951 1.00 79.61  ?  268  LEU Q CD2 1 
ATOM 1616 N N   . LEU A 1 293 ? 127.999 123.186 141.839 1.00 74.50  ?  269  LEU Q N   1 
ATOM 1617 C CA  . LEU A 1 293 ? 128.439 122.294 142.907 1.00 74.50  ?  269  LEU Q CA  1 
ATOM 1618 C C   . LEU A 1 293 ? 128.681 122.988 144.239 1.00 74.50  ?  269  LEU Q C   1 
ATOM 1619 O O   . LEU A 1 293 ? 128.792 122.304 145.261 1.00 74.50  ?  269  LEU Q O   1 
ATOM 1620 C CB  . LEU A 1 293 ? 129.727 121.576 142.501 1.00 74.50  ?  269  LEU Q CB  1 
ATOM 1621 C CG  . LEU A 1 293 ? 129.606 120.114 142.087 1.00 74.50  ?  269  LEU Q CG  1 
ATOM 1622 C CD1 . LEU A 1 293 ? 129.038 119.282 143.225 1.00 74.50  ?  269  LEU Q CD1 1 
ATOM 1623 C CD2 . LEU A 1 293 ? 128.755 119.987 140.847 1.00 74.50  ?  269  LEU Q CD2 1 
ATOM 1624 N N   . GLY A 1 294 ? 128.764 124.314 144.262 1.00 80.20  ?  270  GLY Q N   1 
ATOM 1625 C CA  . GLY A 1 294 ? 129.247 125.020 145.429 1.00 80.20  ?  270  GLY Q CA  1 
ATOM 1626 C C   . GLY A 1 294 ? 128.234 125.119 146.551 1.00 80.20  ?  270  GLY Q C   1 
ATOM 1627 O O   . GLY A 1 294 ? 127.128 124.582 146.497 1.00 80.20  ?  270  GLY Q O   1 
ATOM 1628 N N   . ASP A 1 295 ? 128.641 125.830 147.600 1.00 81.57  ?  271  ASP Q N   1 
ATOM 1629 C CA  . ASP A 1 295 ? 127.807 126.047 148.772 1.00 81.57  ?  271  ASP Q CA  1 
ATOM 1630 C C   . ASP A 1 295 ? 128.230 127.354 149.429 1.00 81.57  ?  271  ASP Q C   1 
ATOM 1631 O O   . ASP A 1 295 ? 129.289 127.909 149.130 1.00 81.57  ?  271  ASP Q O   1 
ATOM 1632 C CB  . ASP A 1 295 ? 127.908 124.874 149.754 1.00 81.57  ?  271  ASP Q CB  1 
ATOM 1633 C CG  . ASP A 1 295 ? 126.864 124.940 150.852 1.00 81.57  ?  271  ASP Q CG  1 
ATOM 1634 O OD1 . ASP A 1 295 ? 127.059 125.713 151.812 1.00 81.57  ?  271  ASP Q OD1 1 
ATOM 1635 O OD2 . ASP A 1 295 ? 125.849 124.219 150.753 1.00 81.57  -1 271  ASP Q OD2 1 
ATOM 1636 N N   . ALA A 1 296 ? 127.379 127.846 150.331 1.00 79.04  ?  272  ALA Q N   1 
ATOM 1637 C CA  . ALA A 1 296 ? 127.635 129.132 150.973 1.00 79.04  ?  272  ALA Q CA  1 
ATOM 1638 C C   . ALA A 1 296 ? 128.909 129.101 151.808 1.00 79.04  ?  272  ALA Q C   1 
ATOM 1639 O O   . ALA A 1 296 ? 129.679 130.068 151.814 1.00 79.04  ?  272  ALA Q O   1 
ATOM 1640 C CB  . ALA A 1 296 ? 126.440 129.534 151.836 1.00 79.04  ?  272  ALA Q CB  1 
ATOM 1641 N N   . HIS A 1 297 ? 129.152 128.000 152.518 1.00 89.83  ?  273  HIS Q N   1 
ATOM 1642 C CA  . HIS A 1 297 ? 130.296 127.883 153.413 1.00 89.83  ?  273  HIS Q CA  1 
ATOM 1643 C C   . HIS A 1 297 ? 131.543 127.363 152.708 1.00 89.83  ?  273  HIS Q C   1 
ATOM 1644 O O   . HIS A 1 297 ? 132.417 126.773 153.355 1.00 89.83  ?  273  HIS Q O   1 
ATOM 1645 C CB  . HIS A 1 297 ? 129.942 126.989 154.601 1.00 89.83  ?  273  HIS Q CB  1 
ATOM 1646 C CG  . HIS A 1 297 ? 128.756 127.465 155.381 1.00 89.83  ?  273  HIS Q CG  1 
ATOM 1647 N ND1 . HIS A 1 297 ? 127.491 127.549 154.839 1.00 89.83  ?  273  HIS Q ND1 1 
ATOM 1648 C CD2 . HIS A 1 297 ? 128.643 127.886 156.663 1.00 89.83  ?  273  HIS Q CD2 1 
ATOM 1649 C CE1 . HIS A 1 297 ? 126.651 127.999 155.753 1.00 89.83  ?  273  HIS Q CE1 1 
ATOM 1650 N NE2 . HIS A 1 297 ? 127.325 128.211 156.869 1.00 89.83  ?  273  HIS Q NE2 1 
ATOM 1651 N N   . SER A 1 298 ? 131.643 127.563 151.399 1.00 86.12  ?  274  SER Q N   1 
ATOM 1652 C CA  . SER A 1 298 ? 132.799 127.101 150.653 1.00 86.12  ?  274  SER Q CA  1 
ATOM 1653 C C   . SER A 1 298 ? 134.030 127.931 151.012 1.00 86.12  ?  274  SER Q C   1 
ATOM 1654 O O   . SER A 1 298 ? 133.909 129.086 151.429 1.00 86.12  ?  274  SER Q O   1 
ATOM 1655 C CB  . SER A 1 298 ? 132.527 127.190 149.154 1.00 86.12  ?  274  SER Q CB  1 
ATOM 1656 O OG  . SER A 1 298 ? 133.630 126.733 148.393 1.00 86.12  ?  274  SER Q OG  1 
ATOM 1657 N N   . PRO A 1 299 ? 135.224 127.358 150.879 1.00 89.68  ?  275  PRO Q N   1 
ATOM 1658 C CA  . PRO A 1 299 ? 136.433 128.135 151.124 1.00 89.68  ?  275  PRO Q CA  1 
ATOM 1659 C C   . PRO A 1 299 ? 136.516 129.309 150.173 1.00 89.68  ?  275  PRO Q C   1 
ATOM 1660 O O   . PRO A 1 299 ? 136.024 129.243 149.030 1.00 89.68  ?  275  PRO Q O   1 
ATOM 1661 C CB  . PRO A 1 299 ? 137.558 127.122 150.871 1.00 89.68  ?  275  PRO Q CB  1 
ATOM 1662 C CG  . PRO A 1 299 ? 136.937 125.806 151.154 1.00 89.68  ?  275  PRO Q CG  1 
ATOM 1663 C CD  . PRO A 1 299 ? 135.508 125.922 150.721 1.00 89.68  ?  275  PRO Q CD  1 
ATOM 1664 N N   . PRO A 1 300 ? 137.131 130.412 150.598 1.00 91.89  ?  276  PRO Q N   1 
ATOM 1665 C CA  . PRO A 1 300 ? 137.072 131.642 149.799 1.00 91.89  ?  276  PRO Q CA  1 
ATOM 1666 C C   . PRO A 1 300 ? 138.018 131.645 148.609 1.00 91.89  ?  276  PRO Q C   1 
ATOM 1667 O O   . PRO A 1 300 ? 137.747 132.313 147.606 1.00 91.89  ?  276  PRO Q O   1 
ATOM 1668 C CB  . PRO A 1 300 ? 137.449 132.739 150.805 1.00 91.89  ?  276  PRO Q CB  1 
ATOM 1669 C CG  . PRO A 1 300 ? 137.825 132.031 152.093 1.00 91.89  ?  276  PRO Q CG  1 
ATOM 1670 C CD  . PRO A 1 300 ? 137.958 130.576 151.800 1.00 91.89  ?  276  PRO Q CD  1 
ATOM 1671 N N   . LEU A 1 301 ? 139.128 130.911 148.700 1.00 91.03  ?  277  LEU Q N   1 
ATOM 1672 C CA  . LEU A 1 301 ? 140.113 130.946 147.626 1.00 91.03  ?  277  LEU Q CA  1 
ATOM 1673 C C   . LEU A 1 301 ? 139.624 130.264 146.356 1.00 91.03  ?  277  LEU Q C   1 
ATOM 1674 O O   . LEU A 1 301 ? 140.130 130.570 145.271 1.00 91.03  ?  277  LEU Q O   1 
ATOM 1675 C CB  . LEU A 1 301 ? 141.428 130.320 148.095 1.00 91.03  ?  277  LEU Q CB  1 
ATOM 1676 C CG  . LEU A 1 301 ? 141.706 128.840 147.828 1.00 91.03  ?  277  LEU Q CG  1 
ATOM 1677 C CD1 . LEU A 1 301 ? 143.130 128.502 148.230 1.00 91.03  ?  277  LEU Q CD1 1 
ATOM 1678 C CD2 . LEU A 1 301 ? 140.736 127.971 148.611 1.00 91.03  ?  277  LEU Q CD2 1 
ATOM 1679 N N   . TYR A 1 302 ? 138.646 129.365 146.462 1.00 89.09  ?  278  TYR Q N   1 
ATOM 1680 C CA  . TYR A 1 302 ? 138.183 128.629 145.293 1.00 89.09  ?  278  TYR Q CA  1 
ATOM 1681 C C   . TYR A 1 302 ? 137.524 129.552 144.273 1.00 89.09  ?  278  TYR Q C   1 
ATOM 1682 O O   . TYR A 1 302 ? 137.788 129.452 143.068 1.00 89.09  ?  278  TYR Q O   1 
ATOM 1683 C CB  . TYR A 1 302 ? 137.223 127.525 145.728 1.00 89.09  ?  278  TYR Q CB  1 
ATOM 1684 C CG  . TYR A 1 302 ? 137.876 126.179 145.927 1.00 89.09  ?  278  TYR Q CG  1 
ATOM 1685 C CD1 . TYR A 1 302 ? 139.244 126.072 146.119 1.00 89.09  ?  278  TYR Q CD1 1 
ATOM 1686 C CD2 . TYR A 1 302 ? 137.123 125.015 145.931 1.00 89.09  ?  278  TYR Q CD2 1 
ATOM 1687 C CE1 . TYR A 1 302 ? 139.844 124.845 146.305 1.00 89.09  ?  278  TYR Q CE1 1 
ATOM 1688 C CE2 . TYR A 1 302 ? 137.713 123.784 146.115 1.00 89.09  ?  278  TYR Q CE2 1 
ATOM 1689 C CZ  . TYR A 1 302 ? 139.075 123.704 146.302 1.00 89.09  ?  278  TYR Q CZ  1 
ATOM 1690 O OH  . TYR A 1 302 ? 139.669 122.477 146.487 1.00 89.09  ?  278  TYR Q OH  1 
ATOM 1691 N N   . THR A 1 303 ? 136.657 130.457 144.735 1.00 84.43  ?  279  THR Q N   1 
ATOM 1692 C CA  . THR A 1 303 ? 135.982 131.363 143.810 1.00 84.43  ?  279  THR Q CA  1 
ATOM 1693 C C   . THR A 1 303 ? 136.973 132.295 143.129 1.00 84.43  ?  279  THR Q C   1 
ATOM 1694 O O   . THR A 1 303 ? 136.869 132.555 141.923 1.00 84.43  ?  279  THR Q O   1 
ATOM 1695 C CB  . THR A 1 303 ? 134.913 132.171 144.541 1.00 84.43  ?  279  THR Q CB  1 
ATOM 1696 O OG1 . THR A 1 303 ? 135.516 133.320 145.146 1.00 84.43  ?  279  THR Q OG1 1 
ATOM 1697 C CG2 . THR A 1 303 ? 134.251 131.328 145.616 1.00 84.43  ?  279  THR Q CG2 1 
ATOM 1698 N N   . TYR A 1 304 ? 137.938 132.813 143.886 1.00 85.97  ?  280  TYR Q N   1 
ATOM 1699 C CA  . TYR A 1 304 ? 138.952 133.676 143.295 1.00 85.97  ?  280  TYR Q CA  1 
ATOM 1700 C C   . TYR A 1 304 ? 139.787 132.918 142.275 1.00 85.97  ?  280  TYR Q C   1 
ATOM 1701 O O   . TYR A 1 304 ? 140.150 133.467 141.229 1.00 85.97  ?  280  TYR Q O   1 
ATOM 1702 C CB  . TYR A 1 304 ? 139.835 134.267 144.389 1.00 85.97  ?  280  TYR Q CB  1 
ATOM 1703 C CG  . TYR A 1 304 ? 139.362 135.612 144.876 1.00 85.97  ?  280  TYR Q CG  1 
ATOM 1704 C CD1 . TYR A 1 304 ? 138.229 136.203 144.341 1.00 85.97  ?  280  TYR Q CD1 1 
ATOM 1705 C CD2 . TYR A 1 304 ? 140.036 136.282 145.882 1.00 85.97  ?  280  TYR Q CD2 1 
ATOM 1706 C CE1 . TYR A 1 304 ? 137.789 137.433 144.784 1.00 85.97  ?  280  TYR Q CE1 1 
ATOM 1707 C CE2 . TYR A 1 304 ? 139.606 137.512 146.332 1.00 85.97  ?  280  TYR Q CE2 1 
ATOM 1708 C CZ  . TYR A 1 304 ? 138.480 138.083 145.780 1.00 85.97  ?  280  TYR Q CZ  1 
ATOM 1709 O OH  . TYR A 1 304 ? 138.044 139.309 146.227 1.00 85.97  ?  280  TYR Q OH  1 
ATOM 1710 N N   . LEU A 1 305 ? 140.108 131.655 142.562 1.00 89.81  ?  281  LEU Q N   1 
ATOM 1711 C CA  . LEU A 1 305 ? 140.866 130.858 141.605 1.00 89.81  ?  281  LEU Q CA  1 
ATOM 1712 C C   . LEU A 1 305 ? 140.070 130.617 140.329 1.00 89.81  ?  281  LEU Q C   1 
ATOM 1713 O O   . LEU A 1 305 ? 140.626 130.674 139.227 1.00 89.81  ?  281  LEU Q O   1 
ATOM 1714 C CB  . LEU A 1 305 ? 141.279 129.531 142.239 1.00 89.81  ?  281  LEU Q CB  1 
ATOM 1715 C CG  . LEU A 1 305 ? 142.429 128.784 141.560 1.00 89.81  ?  281  LEU Q CG  1 
ATOM 1716 C CD1 . LEU A 1 305 ? 143.388 128.222 142.599 1.00 89.81  ?  281  LEU Q CD1 1 
ATOM 1717 C CD2 . LEU A 1 305 ? 141.899 127.675 140.664 1.00 89.81  ?  281  LEU Q CD2 1 
ATOM 1718 N N   . THR A 1 306 ? 138.771 130.345 140.453 1.00 89.42  ?  282  THR Q N   1 
ATOM 1719 C CA  . THR A 1 306 ? 137.987 129.997 139.274 1.00 89.42  ?  282  THR Q CA  1 
ATOM 1720 C C   . THR A 1 306 ? 137.478 131.207 138.500 1.00 89.42  ?  282  THR Q C   1 
ATOM 1721 O O   . THR A 1 306 ? 137.016 131.038 137.368 1.00 89.42  ?  282  THR Q O   1 
ATOM 1722 C CB  . THR A 1 306 ? 136.794 129.120 139.658 1.00 89.42  ?  282  THR Q CB  1 
ATOM 1723 O OG1 . THR A 1 306 ? 136.125 128.683 138.469 1.00 89.42  ?  282  THR Q OG1 1 
ATOM 1724 C CG2 . THR A 1 306 ? 135.812 129.903 140.502 1.00 89.42  ?  282  THR Q CG2 1 
ATOM 1725 N N   . LEU A 1 307 ? 137.536 132.412 139.068 1.00 85.21  ?  283  LEU Q N   1 
ATOM 1726 C CA  . LEU A 1 307 ? 137.049 133.574 138.334 1.00 85.21  ?  283  LEU Q CA  1 
ATOM 1727 C C   . LEU A 1 307 ? 138.074 134.148 137.365 1.00 85.21  ?  283  LEU Q C   1 
ATOM 1728 O O   . LEU A 1 307 ? 137.703 134.946 136.499 1.00 85.21  ?  283  LEU Q O   1 
ATOM 1729 C CB  . LEU A 1 307 ? 136.604 134.664 139.307 1.00 85.21  ?  283  LEU Q CB  1 
ATOM 1730 C CG  . LEU A 1 307 ? 135.515 135.603 138.789 1.00 85.21  ?  283  LEU Q CG  1 
ATOM 1731 C CD1 . LEU A 1 307 ? 134.450 134.822 138.045 1.00 85.21  ?  283  LEU Q CD1 1 
ATOM 1732 C CD2 . LEU A 1 307 ? 134.901 136.397 139.928 1.00 85.21  ?  283  LEU Q CD2 1 
ATOM 1733 N N   . LEU A 1 308 ? 139.345 133.771 137.490 1.00 91.73  ?  284  LEU Q N   1 
ATOM 1734 C CA  . LEU A 1 308 ? 140.364 134.290 136.579 1.00 91.73  ?  284  LEU Q CA  1 
ATOM 1735 C C   . LEU A 1 308 ? 140.146 133.904 135.117 1.00 91.73  ?  284  LEU Q C   1 
ATOM 1736 O O   . LEU A 1 308 ? 140.329 134.777 134.247 1.00 91.73  ?  284  LEU Q O   1 
ATOM 1737 C CB  . LEU A 1 308 ? 141.753 133.841 137.049 1.00 91.73  ?  284  LEU Q CB  1 
ATOM 1738 C CG  . LEU A 1 308 ? 142.602 134.875 137.790 1.00 91.73  ?  284  LEU Q CG  1 
ATOM 1739 C CD1 . LEU A 1 308 ? 143.249 135.842 136.809 1.00 91.73  ?  284  LEU Q CD1 1 
ATOM 1740 C CD2 . LEU A 1 308 ? 141.775 135.622 138.821 1.00 91.73  ?  284  LEU Q CD2 1 
ATOM 1741 N N   . PRO A 1 309 ? 139.792 132.660 134.770 1.00 89.20  ?  285  PRO Q N   1 
ATOM 1742 C CA  . PRO A 1 309 ? 139.657 132.322 133.345 1.00 89.20  ?  285  PRO Q CA  1 
ATOM 1743 C C   . PRO A 1 309 ? 138.631 133.157 132.601 1.00 89.20  ?  285  PRO Q C   1 
ATOM 1744 O O   . PRO A 1 309 ? 138.769 133.331 131.385 1.00 89.20  ?  285  PRO Q O   1 
ATOM 1745 C CB  . PRO A 1 309 ? 139.261 130.840 133.378 1.00 89.20  ?  285  PRO Q CB  1 
ATOM 1746 C CG  . PRO A 1 309 ? 139.842 130.337 134.636 1.00 89.20  ?  285  PRO Q CG  1 
ATOM 1747 C CD  . PRO A 1 309 ? 139.680 131.457 135.614 1.00 89.20  ?  285  PRO Q CD  1 
ATOM 1748 N N   . ALA A 1 310 ? 137.608 133.679 133.277 1.00 90.16  ?  286  ALA Q N   1 
ATOM 1749 C CA  . ALA A 1 310 ? 136.648 134.537 132.591 1.00 90.16  ?  286  ALA Q CA  1 
ATOM 1750 C C   . ALA A 1 310 ? 137.324 135.796 132.059 1.00 90.16  ?  286  ALA Q C   1 
ATOM 1751 O O   . ALA A 1 310 ? 137.180 136.148 130.880 1.00 90.16  ?  286  ALA Q O   1 
ATOM 1752 C CB  . ALA A 1 310 ? 135.500 134.894 133.533 1.00 90.16  ?  286  ALA Q CB  1 
ATOM 1753 N N   . THR A 1 311 ? 138.091 136.477 132.912 1.00 95.57  ?  287  THR Q N   1 
ATOM 1754 C CA  . THR A 1 311 ? 138.821 137.655 132.460 1.00 95.57  ?  287  THR Q CA  1 
ATOM 1755 C C   . THR A 1 311 ? 139.903 137.290 131.453 1.00 95.57  ?  287  THR Q C   1 
ATOM 1756 O O   . THR A 1 311 ? 140.183 138.069 130.531 1.00 95.57  ?  287  THR Q O   1 
ATOM 1757 C CB  . THR A 1 311 ? 139.431 138.384 133.653 1.00 95.57  ?  287  THR Q CB  1 
ATOM 1758 O OG1 . THR A 1 311 ? 140.346 137.512 134.327 1.00 95.57  ?  287  THR Q OG1 1 
ATOM 1759 C CG2 . THR A 1 311 ? 138.345 138.812 134.622 1.00 95.57  ?  287  THR Q CG2 1 
ATOM 1760 N N   . TYR A 1 312 ? 140.516 136.114 131.604 1.00 102.33 ?  288  TYR Q N   1 
ATOM 1761 C CA  . TYR A 1 312 ? 141.502 135.682 130.619 1.00 102.33 ?  288  TYR Q CA  1 
ATOM 1762 C C   . TYR A 1 312 ? 140.869 135.520 129.241 1.00 102.33 ?  288  TYR Q C   1 
ATOM 1763 O O   . TYR A 1 312 ? 141.448 135.936 128.233 1.00 102.33 ?  288  TYR Q O   1 
ATOM 1764 C CB  . TYR A 1 312 ? 142.162 134.381 131.071 1.00 102.33 ?  288  TYR Q CB  1 
ATOM 1765 C CG  . TYR A 1 312 ? 143.400 134.598 131.909 1.00 102.33 ?  288  TYR Q CG  1 
ATOM 1766 C CD1 . TYR A 1 312 ? 143.924 135.870 132.090 1.00 102.33 ?  288  TYR Q CD1 1 
ATOM 1767 C CD2 . TYR A 1 312 ? 144.046 133.531 132.519 1.00 102.33 ?  288  TYR Q CD2 1 
ATOM 1768 C CE1 . TYR A 1 312 ? 145.055 136.075 132.855 1.00 102.33 ?  288  TYR Q CE1 1 
ATOM 1769 C CE2 . TYR A 1 312 ? 145.178 133.725 133.286 1.00 102.33 ?  288  TYR Q CE2 1 
ATOM 1770 C CZ  . TYR A 1 312 ? 145.678 134.999 133.450 1.00 102.33 ?  288  TYR Q CZ  1 
ATOM 1771 O OH  . TYR A 1 312 ? 146.806 135.199 134.213 1.00 102.33 ?  288  TYR Q OH  1 
ATOM 1772 N N   . ASN A 1 313 ? 139.678 134.922 129.177 1.00 95.01  ?  289  ASN Q N   1 
ATOM 1773 C CA  . ASN A 1 313 ? 138.978 134.811 127.902 1.00 95.01  ?  289  ASN Q CA  1 
ATOM 1774 C C   . ASN A 1 313 ? 138.600 136.184 127.373 1.00 95.01  ?  289  ASN Q C   1 
ATOM 1775 O O   . ASN A 1 313 ? 138.661 136.431 126.163 1.00 95.01  ?  289  ASN Q O   1 
ATOM 1776 C CB  . ASN A 1 313 ? 137.734 133.935 128.051 1.00 95.01  ?  289  ASN Q CB  1 
ATOM 1777 C CG  . ASN A 1 313 ? 136.761 134.084 126.890 1.00 95.01  ?  289  ASN Q CG  1 
ATOM 1778 O OD1 . ASN A 1 313 ? 136.059 135.088 126.768 1.00 95.01  ?  289  ASN Q OD1 1 
ATOM 1779 N ND2 . ASN A 1 313 ? 136.717 133.075 126.029 1.00 95.01  ?  289  ASN Q ND2 1 
ATOM 1780 N N   . SER A 1 314 ? 138.182 137.084 128.264 1.00 94.18  ?  290  SER Q N   1 
ATOM 1781 C CA  . SER A 1 314 ? 137.848 138.437 127.836 1.00 94.18  ?  290  SER Q CA  1 
ATOM 1782 C C   . SER A 1 314 ? 139.041 139.114 127.176 1.00 94.18  ?  290  SER Q C   1 
ATOM 1783 O O   . SER A 1 314 ? 138.883 139.856 126.201 1.00 94.18  ?  290  SER Q O   1 
ATOM 1784 C CB  . SER A 1 314 ? 137.360 139.258 129.026 1.00 94.18  ?  290  SER Q CB  1 
ATOM 1785 O OG  . SER A 1 314 ? 137.734 140.616 128.886 1.00 94.18  ?  290  SER Q OG  1 
ATOM 1786 N N   . MET A 1 315 ? 140.245 138.875 127.697 1.00 101.81 ?  291  MET Q N   1 
ATOM 1787 C CA  . MET A 1 315 ? 141.432 139.466 127.085 1.00 101.81 ?  291  MET Q CA  1 
ATOM 1788 C C   . MET A 1 315 ? 141.845 138.733 125.812 1.00 101.81 ?  291  MET Q C   1 
ATOM 1789 O O   . MET A 1 315 ? 142.346 139.365 124.876 1.00 101.81 ?  291  MET Q O   1 
ATOM 1790 C CB  . MET A 1 315 ? 142.576 139.520 128.111 1.00 101.81 ?  291  MET Q CB  1 
ATOM 1791 C CG  . MET A 1 315 ? 144.024 139.406 127.593 1.00 101.81 ?  291  MET Q CG  1 
ATOM 1792 S SD  . MET A 1 315 ? 144.614 137.825 126.944 1.00 101.81 ?  291  MET Q SD  1 
ATOM 1793 C CE  . MET A 1 315 ? 144.467 136.787 128.395 1.00 101.81 ?  291  MET Q CE  1 
ATOM 1794 N N   . ILE A 1 316 ? 141.652 137.414 125.762 1.00 95.90  ?  292  ILE Q N   1 
ATOM 1795 C CA  . ILE A 1 316 ? 142.086 136.631 124.607 1.00 95.90  ?  292  ILE Q CA  1 
ATOM 1796 C C   . ILE A 1 316 ? 141.211 136.911 123.391 1.00 95.90  ?  292  ILE Q C   1 
ATOM 1797 O O   . ILE A 1 316 ? 141.714 137.045 122.269 1.00 95.90  ?  292  ILE Q O   1 
ATOM 1798 C CB  . ILE A 1 316 ? 142.099 135.132 124.961 1.00 95.90  ?  292  ILE Q CB  1 
ATOM 1799 C CG1 . ILE A 1 316 ? 143.459 134.727 125.530 1.00 95.90  ?  292  ILE Q CG1 1 
ATOM 1800 C CG2 . ILE A 1 316 ? 141.751 134.280 123.747 1.00 95.90  ?  292  ILE Q CG2 1 
ATOM 1801 C CD1 . ILE A 1 316 ? 143.444 133.405 126.262 1.00 95.90  ?  292  ILE Q CD1 1 
ATOM 1802 N N   . ASN A 1 317 ? 139.899 137.024 123.594 1.00 92.17  ?  293  ASN Q N   1 
ATOM 1803 C CA  . ASN A 1 317 ? 138.937 137.004 122.491 1.00 92.17  ?  293  ASN Q CA  1 
ATOM 1804 C C   . ASN A 1 317 ? 139.184 138.047 121.402 1.00 92.17  ?  293  ASN Q C   1 
ATOM 1805 O O   . ASN A 1 317 ? 139.056 137.698 120.217 1.00 92.17  ?  293  ASN Q O   1 
ATOM 1806 C CB  . ASN A 1 317 ? 137.528 137.107 123.096 1.00 92.17  ?  293  ASN Q CB  1 
ATOM 1807 C CG  . ASN A 1 317 ? 136.477 137.596 122.110 1.00 92.17  ?  293  ASN Q CG  1 
ATOM 1808 O OD1 . ASN A 1 317 ? 136.591 138.665 121.515 1.00 92.17  ?  293  ASN Q OD1 1 
ATOM 1809 N ND2 . ASN A 1 317 ? 135.440 136.790 121.929 1.00 92.17  ?  293  ASN Q ND2 1 
ATOM 1810 N N   . PRO A 1 318 ? 139.480 139.319 121.698 1.00 95.81  ?  294  PRO Q N   1 
ATOM 1811 C CA  . PRO A 1 318 ? 139.657 140.277 120.595 1.00 95.81  ?  294  PRO Q CA  1 
ATOM 1812 C C   . PRO A 1 318 ? 140.898 140.028 119.760 1.00 95.81  ?  294  PRO Q C   1 
ATOM 1813 O O   . PRO A 1 318 ? 140.935 140.453 118.600 1.00 95.81  ?  294  PRO Q O   1 
ATOM 1814 C CB  . PRO A 1 318 ? 139.721 141.639 121.298 1.00 95.81  ?  294  PRO Q CB  1 
ATOM 1815 C CG  . PRO A 1 318 ? 139.931 141.366 122.726 1.00 95.81  ?  294  PRO Q CG  1 
ATOM 1816 C CD  . PRO A 1 318 ? 139.838 139.910 122.998 1.00 95.81  ?  294  PRO Q CD  1 
ATOM 1817 N N   . ILE A 1 319 ? 141.914 139.357 120.302 1.00 99.68  ?  295  ILE Q N   1 
ATOM 1818 C CA  . ILE A 1 319 ? 143.081 139.028 119.492 1.00 99.68  ?  295  ILE Q CA  1 
ATOM 1819 C C   . ILE A 1 319 ? 142.741 137.954 118.470 1.00 99.68  ?  295  ILE Q C   1 
ATOM 1820 O O   . ILE A 1 319 ? 143.325 137.918 117.380 1.00 99.68  ?  295  ILE Q O   1 
ATOM 1821 C CB  . ILE A 1 319 ? 144.253 138.596 120.391 1.00 99.68  ?  295  ILE Q CB  1 
ATOM 1822 C CG1 . ILE A 1 319 ? 144.240 139.386 121.701 1.00 99.68  ?  295  ILE Q CG1 1 
ATOM 1823 C CG2 . ILE A 1 319 ? 145.577 138.777 119.663 1.00 99.68  ?  295  ILE Q CG2 1 
ATOM 1824 C CD1 . ILE A 1 319 ? 145.468 139.173 122.558 1.00 99.68  ?  295  ILE Q CD1 1 
ATOM 1825 N N   . ILE A 1 320 ? 141.803 137.067 118.794 1.00 93.34  ?  296  ILE Q N   1 
ATOM 1826 C CA  . ILE A 1 320 ? 141.521 135.911 117.952 1.00 93.34  ?  296  ILE Q CA  1 
ATOM 1827 C C   . ILE A 1 320 ? 140.321 136.121 117.031 1.00 93.34  ?  296  ILE Q C   1 
ATOM 1828 O O   . ILE A 1 320 ? 140.259 135.494 115.963 1.00 93.34  ?  296  ILE Q O   1 
ATOM 1829 C CB  . ILE A 1 320 ? 141.337 134.652 118.831 1.00 93.34  ?  296  ILE Q CB  1 
ATOM 1830 C CG1 . ILE A 1 320 ? 140.675 133.502 118.075 1.00 93.34  ?  296  ILE Q CG1 1 
ATOM 1831 C CG2 . ILE A 1 320 ? 140.537 134.969 120.071 1.00 93.34  ?  296  ILE Q CG2 1 
ATOM 1832 C CD1 . ILE A 1 320 ? 140.571 132.247 118.898 1.00 93.34  ?  296  ILE Q CD1 1 
ATOM 1833 N N   . TYR A 1 321 ? 139.392 137.008 117.381 1.00 84.53  ?  297  TYR Q N   1 
ATOM 1834 C CA  . TYR A 1 321 ? 138.234 137.236 116.529 1.00 84.53  ?  297  TYR Q CA  1 
ATOM 1835 C C   . TYR A 1 321 ? 138.265 138.556 115.775 1.00 84.53  ?  297  TYR Q C   1 
ATOM 1836 O O   . TYR A 1 321 ? 137.448 138.743 114.868 1.00 84.53  ?  297  TYR Q O   1 
ATOM 1837 C CB  . TYR A 1 321 ? 136.942 137.158 117.353 1.00 84.53  ?  297  TYR Q CB  1 
ATOM 1838 C CG  . TYR A 1 321 ? 136.190 135.865 117.158 1.00 84.53  ?  297  TYR Q CG  1 
ATOM 1839 C CD1 . TYR A 1 321 ? 135.633 135.546 115.931 1.00 84.53  ?  297  TYR Q CD1 1 
ATOM 1840 C CD2 . TYR A 1 321 ? 136.042 134.962 118.197 1.00 84.53  ?  297  TYR Q CD2 1 
ATOM 1841 C CE1 . TYR A 1 321 ? 134.950 134.366 115.746 1.00 84.53  ?  297  TYR Q CE1 1 
ATOM 1842 C CE2 . TYR A 1 321 ? 135.360 133.780 118.021 1.00 84.53  ?  297  TYR Q CE2 1 
ATOM 1843 C CZ  . TYR A 1 321 ? 134.815 133.487 116.793 1.00 84.53  ?  297  TYR Q CZ  1 
ATOM 1844 O OH  . TYR A 1 321 ? 134.132 132.308 116.610 1.00 84.53  ?  297  TYR Q OH  1 
ATOM 1845 N N   . ALA A 1 322 ? 139.174 139.468 116.108 1.00 102.41 ?  298  ALA Q N   1 
ATOM 1846 C CA  . ALA A 1 322 ? 139.220 140.771 115.455 1.00 102.41 ?  298  ALA Q CA  1 
ATOM 1847 C C   . ALA A 1 322 ? 140.529 141.026 114.727 1.00 102.41 ?  298  ALA Q C   1 
ATOM 1848 O O   . ALA A 1 322 ? 140.512 141.446 113.564 1.00 102.41 ?  298  ALA Q O   1 
ATOM 1849 C CB  . ALA A 1 322 ? 138.966 141.884 116.483 1.00 102.41 ?  298  ALA Q CB  1 
ATOM 1850 N N   . PHE A 1 323 ? 141.670 140.790 115.377 1.00 114.16 ?  299  PHE Q N   1 
ATOM 1851 C CA  . PHE A 1 323 ? 142.956 141.058 114.743 1.00 114.16 ?  299  PHE Q CA  1 
ATOM 1852 C C   . PHE A 1 323 ? 143.276 140.077 113.625 1.00 114.16 ?  299  PHE Q C   1 
ATOM 1853 O O   . PHE A 1 323 ? 144.076 140.405 112.743 1.00 114.16 ?  299  PHE Q O   1 
ATOM 1854 C CB  . PHE A 1 323 ? 144.074 141.022 115.783 1.00 114.16 ?  299  PHE Q CB  1 
ATOM 1855 C CG  . PHE A 1 323 ? 144.177 142.270 116.605 1.00 114.16 ?  299  PHE Q CG  1 
ATOM 1856 C CD1 . PHE A 1 323 ? 143.388 143.372 116.322 1.00 114.16 ?  299  PHE Q CD1 1 
ATOM 1857 C CD2 . PHE A 1 323 ? 145.065 142.343 117.665 1.00 114.16 ?  299  PHE Q CD2 1 
ATOM 1858 C CE1 . PHE A 1 323 ? 143.483 144.522 117.080 1.00 114.16 ?  299  PHE Q CE1 1 
ATOM 1859 C CE2 . PHE A 1 323 ? 145.166 143.490 118.426 1.00 114.16 ?  299  PHE Q CE2 1 
ATOM 1860 C CZ  . PHE A 1 323 ? 144.374 144.580 118.133 1.00 114.16 ?  299  PHE Q CZ  1 
ATOM 1861 N N   . ARG A 1 324 ? 142.681 138.882 113.645 1.00 117.10 ?  300  ARG Q N   1 
ATOM 1862 C CA  . ARG A 1 324 ? 142.984 137.888 112.620 1.00 117.10 ?  300  ARG Q CA  1 
ATOM 1863 C C   . ARG A 1 324 ? 142.531 138.354 111.243 1.00 117.10 ?  300  ARG Q C   1 
ATOM 1864 O O   . ARG A 1 324 ? 143.184 138.057 110.235 1.00 117.10 ?  300  ARG Q O   1 
ATOM 1865 C CB  . ARG A 1 324 ? 142.338 136.551 112.978 1.00 117.10 ?  300  ARG Q CB  1 
ATOM 1866 C CG  . ARG A 1 324 ? 142.823 135.969 114.293 1.00 117.10 ?  300  ARG Q CG  1 
ATOM 1867 C CD  . ARG A 1 324 ? 144.306 135.650 114.245 1.00 117.10 ?  300  ARG Q CD  1 
ATOM 1868 N NE  . ARG A 1 324 ? 144.624 134.727 113.162 1.00 117.10 ?  300  ARG Q NE  1 
ATOM 1869 C CZ  . ARG A 1 324 ? 144.591 133.406 113.272 1.00 117.10 ?  300  ARG Q CZ  1 
ATOM 1870 N NH1 . ARG A 1 324 ? 144.258 132.815 114.408 1.00 117.10 1  300  ARG Q NH1 1 
ATOM 1871 N NH2 . ARG A 1 324 ? 144.899 132.659 112.216 1.00 117.10 ?  300  ARG Q NH2 1 
ATOM 1872 N N   . ASN A 1 325 ? 141.410 139.069 111.175 1.00 115.85 ?  301  ASN Q N   1 
ATOM 1873 C CA  . ASN A 1 325 ? 140.953 139.622 109.908 1.00 115.85 ?  301  ASN Q CA  1 
ATOM 1874 C C   . ASN A 1 325 ? 142.021 140.547 109.344 1.00 115.85 ?  301  ASN Q C   1 
ATOM 1875 O O   . ASN A 1 325 ? 142.498 141.454 110.034 1.00 115.85 ?  301  ASN Q O   1 
ATOM 1876 C CB  . ASN A 1 325 ? 139.630 140.362 110.105 1.00 115.85 ?  301  ASN Q CB  1 
ATOM 1877 C CG  . ASN A 1 325 ? 139.397 141.448 109.069 1.00 115.85 ?  301  ASN Q CG  1 
ATOM 1878 O OD1 . ASN A 1 325 ? 140.011 142.515 109.111 1.00 115.85 ?  301  ASN Q OD1 1 
ATOM 1879 N ND2 . ASN A 1 325 ? 138.504 141.175 108.127 1.00 115.85 ?  301  ASN Q ND2 1 
ATOM 1880 N N   . GLN A 1 326 ? 142.393 140.320 108.087 1.00 121.26 ?  302  GLN Q N   1 
ATOM 1881 C CA  . GLN A 1 326 ? 143.541 141.002 107.509 1.00 121.26 ?  302  GLN Q CA  1 
ATOM 1882 C C   . GLN A 1 326 ? 143.259 142.448 107.123 1.00 121.26 ?  302  GLN Q C   1 
ATOM 1883 O O   . GLN A 1 326 ? 144.210 143.208 106.933 1.00 121.26 ?  302  GLN Q O   1 
ATOM 1884 C CB  . GLN A 1 326 ? 144.046 140.228 106.288 1.00 121.26 ?  302  GLN Q CB  1 
ATOM 1885 C CG  . GLN A 1 326 ? 143.109 140.248 105.096 1.00 121.26 ?  302  GLN Q CG  1 
ATOM 1886 C CD  . GLN A 1 326 ? 143.766 139.714 103.838 1.00 121.26 ?  302  GLN Q CD  1 
ATOM 1887 O OE1 . GLN A 1 326 ? 144.939 139.341 103.848 1.00 121.26 ?  302  GLN Q OE1 1 
ATOM 1888 N NE2 . GLN A 1 326 ? 143.011 139.674 102.747 1.00 121.26 ?  302  GLN Q NE2 1 
ATOM 1889 N N   . ASP A 1 327 ? 141.993 142.847 106.995 1.00 120.18 ?  303  ASP Q N   1 
ATOM 1890 C CA  . ASP A 1 327 ? 141.695 144.242 106.682 1.00 120.18 ?  303  ASP Q CA  1 
ATOM 1891 C C   . ASP A 1 327 ? 142.128 145.160 107.818 1.00 120.18 ?  303  ASP Q C   1 
ATOM 1892 O O   . ASP A 1 327 ? 142.745 146.209 107.588 1.00 120.18 ?  303  ASP Q O   1 
ATOM 1893 C CB  . ASP A 1 327 ? 140.205 144.403 106.389 1.00 120.18 ?  303  ASP Q CB  1 
ATOM 1894 C CG  . ASP A 1 327 ? 139.643 143.249 105.584 1.00 120.18 ?  303  ASP Q CG  1 
ATOM 1895 O OD1 . ASP A 1 327 ? 139.702 142.100 106.070 1.00 120.18 ?  303  ASP Q OD1 1 
ATOM 1896 O OD2 . ASP A 1 327 ? 139.143 143.489 104.465 1.00 120.18 -1 303  ASP Q OD2 1 
ATOM 1897 N N   . VAL A 1 328 ? 141.821 144.774 109.057 1.00 121.23 ?  304  VAL Q N   1 
ATOM 1898 C CA  . VAL A 1 328 ? 142.299 145.537 110.202 1.00 121.23 ?  304  VAL Q CA  1 
ATOM 1899 C C   . VAL A 1 328 ? 143.818 145.514 110.248 1.00 121.23 ?  304  VAL Q C   1 
ATOM 1900 O O   . VAL A 1 328 ? 144.451 146.492 110.663 1.00 121.23 ?  304  VAL Q O   1 
ATOM 1901 C CB  . VAL A 1 328 ? 141.683 144.995 111.507 1.00 121.23 ?  304  VAL Q CB  1 
ATOM 1902 C CG1 . VAL A 1 328 ? 142.014 145.912 112.675 1.00 121.23 ?  304  VAL Q CG1 1 
ATOM 1903 C CG2 . VAL A 1 328 ? 140.178 144.843 111.358 1.00 121.23 ?  304  VAL Q CG2 1 
ATOM 1904 N N   . GLN A 1 329 ? 144.428 144.406 109.824 1.00 121.76 ?  305  GLN Q N   1 
ATOM 1905 C CA  . GLN A 1 329 ? 145.883 144.350 109.766 1.00 121.76 ?  305  GLN Q CA  1 
ATOM 1906 C C   . GLN A 1 329 ? 146.427 145.367 108.772 1.00 121.76 ?  305  GLN Q C   1 
ATOM 1907 O O   . GLN A 1 329 ? 147.439 146.023 109.036 1.00 121.76 ?  305  GLN Q O   1 
ATOM 1908 C CB  . GLN A 1 329 ? 146.343 142.936 109.412 1.00 121.76 ?  305  GLN Q CB  1 
ATOM 1909 C CG  . GLN A 1 329 ? 147.525 142.876 108.457 1.00 121.76 ?  305  GLN Q CG  1 
ATOM 1910 C CD  . GLN A 1 329 ? 147.737 141.493 107.876 1.00 121.76 ?  305  GLN Q CD  1 
ATOM 1911 O OE1 . GLN A 1 329 ? 146.837 140.654 107.896 1.00 121.76 ?  305  GLN Q OE1 1 
ATOM 1912 N NE2 . GLN A 1 329 ? 148.933 141.249 107.353 1.00 121.76 ?  305  GLN Q NE2 1 
ATOM 1913 N N   . LYS A 1 330 ? 145.763 145.516 107.622 1.00 123.64 ?  306  LYS Q N   1 
ATOM 1914 C CA  . LYS A 1 330 ? 146.171 146.533 106.658 1.00 123.64 ?  306  LYS Q CA  1 
ATOM 1915 C C   . LYS A 1 330 ? 146.016 147.930 107.239 1.00 123.64 ?  306  LYS Q C   1 
ATOM 1916 O O   . LYS A 1 330 ? 146.875 148.795 107.035 1.00 123.64 ?  306  LYS Q O   1 
ATOM 1917 C CB  . LYS A 1 330 ? 145.359 146.406 105.369 1.00 123.64 ?  306  LYS Q CB  1 
ATOM 1918 C CG  . LYS A 1 330 ? 145.456 145.059 104.680 1.00 123.64 ?  306  LYS Q CG  1 
ATOM 1919 C CD  . LYS A 1 330 ? 144.294 144.863 103.719 1.00 123.64 ?  306  LYS Q CD  1 
ATOM 1920 C CE  . LYS A 1 330 ? 143.915 143.400 103.593 1.00 123.64 ?  306  LYS Q CE  1 
ATOM 1921 N NZ  . LYS A 1 330 ? 142.468 143.227 103.288 1.00 123.64 1  306  LYS Q NZ  1 
ATOM 1922 N N   . VAL A 1 331 ? 144.917 148.172 107.956 1.00 120.48 ?  307  VAL Q N   1 
ATOM 1923 C CA  . VAL A 1 331 ? 144.710 149.482 108.570 1.00 120.48 ?  307  VAL Q CA  1 
ATOM 1924 C C   . VAL A 1 331 ? 145.825 149.782 109.565 1.00 120.48 ?  307  VAL Q C   1 
ATOM 1925 O O   . VAL A 1 331 ? 146.386 150.885 109.587 1.00 120.48 ?  307  VAL Q O   1 
ATOM 1926 C CB  . VAL A 1 331 ? 143.325 149.554 109.237 1.00 120.48 ?  307  VAL Q CB  1 
ATOM 1927 C CG1 . VAL A 1 331 ? 143.109 150.927 109.851 1.00 120.48 ?  307  VAL Q CG1 1 
ATOM 1928 C CG2 . VAL A 1 331 ? 142.237 149.255 108.224 1.00 120.48 ?  307  VAL Q CG2 1 
ATOM 1929 N N   . LEU A 1 332 ? 146.168 148.799 110.397 1.00 123.64 ?  308  LEU Q N   1 
ATOM 1930 C CA  . LEU A 1 332 ? 147.236 148.989 111.373 1.00 123.64 ?  308  LEU Q CA  1 
ATOM 1931 C C   . LEU A 1 332 ? 148.577 149.213 110.688 1.00 123.64 ?  308  LEU Q C   1 
ATOM 1932 O O   . LEU A 1 332 ? 149.355 150.081 111.099 1.00 123.64 ?  308  LEU Q O   1 
ATOM 1933 C CB  . LEU A 1 332 ? 147.313 147.784 112.309 1.00 123.64 ?  308  LEU Q CB  1 
ATOM 1934 C CG  . LEU A 1 332 ? 146.624 147.917 113.668 1.00 123.64 ?  308  LEU Q CG  1 
ATOM 1935 C CD1 . LEU A 1 332 ? 145.129 148.096 113.484 1.00 123.64 ?  308  LEU Q CD1 1 
ATOM 1936 C CD2 . LEU A 1 332 ? 146.920 146.711 114.545 1.00 123.64 ?  308  LEU Q CD2 1 
ATOM 1937 N N   . TRP A 1 333 ? 148.865 148.436 109.642 1.00 125.59 ?  309  TRP Q N   1 
ATOM 1938 C CA  . TRP A 1 333 ? 150.138 148.567 108.944 1.00 125.59 ?  309  TRP Q CA  1 
ATOM 1939 C C   . TRP A 1 333 ? 150.261 149.930 108.279 1.00 125.59 ?  309  TRP Q C   1 
ATOM 1940 O O   . TRP A 1 333 ? 151.343 150.528 108.267 1.00 125.59 ?  309  TRP Q O   1 
ATOM 1941 C CB  . TRP A 1 333 ? 150.285 147.445 107.917 1.00 125.59 ?  309  TRP Q CB  1 
ATOM 1942 C CG  . TRP A 1 333 ? 151.698 147.170 107.463 1.00 125.59 ?  309  TRP Q CG  1 
ATOM 1943 C CD1 . TRP A 1 333 ? 152.091 146.835 106.200 1.00 125.59 ?  309  TRP Q CD1 1 
ATOM 1944 C CD2 . TRP A 1 333 ? 152.893 147.174 108.264 1.00 125.59 ?  309  TRP Q CD2 1 
ATOM 1945 N NE1 . TRP A 1 333 ? 153.450 146.648 106.159 1.00 125.59 ?  309  TRP Q NE1 1 
ATOM 1946 C CE2 . TRP A 1 333 ? 153.966 146.848 107.412 1.00 125.59 ?  309  TRP Q CE2 1 
ATOM 1947 C CE3 . TRP A 1 333 ? 153.160 147.425 109.615 1.00 125.59 ?  309  TRP Q CE3 1 
ATOM 1948 C CZ2 . TRP A 1 333 ? 155.281 146.768 107.863 1.00 125.59 ?  309  TRP Q CZ2 1 
ATOM 1949 C CZ3 . TRP A 1 333 ? 154.466 147.348 110.059 1.00 125.59 ?  309  TRP Q CZ3 1 
ATOM 1950 C CH2 . TRP A 1 333 ? 155.510 147.021 109.187 1.00 125.59 ?  309  TRP Q CH2 1 
ATOM 1951 N N   . ALA A 1 334 ? 149.163 150.434 107.710 1.00 130.52 ?  310  ALA Q N   1 
ATOM 1952 C CA  . ALA A 1 334 ? 149.161 151.799 107.197 1.00 130.52 ?  310  ALA Q CA  1 
ATOM 1953 C C   . ALA A 1 334 ? 149.389 152.800 108.321 1.00 130.52 ?  310  ALA Q C   1 
ATOM 1954 O O   . ALA A 1 334 ? 150.119 153.784 108.150 1.00 130.52 ?  310  ALA Q O   1 
ATOM 1955 C CB  . ALA A 1 334 ? 147.846 152.089 106.473 1.00 130.52 ?  310  ALA Q CB  1 
ATOM 1956 N N   . VAL A 1 335 ? 148.768 152.567 109.478 1.00 128.68 ?  311  VAL Q N   1 
ATOM 1957 C CA  . VAL A 1 335 ? 149.050 153.392 110.648 1.00 128.68 ?  311  VAL Q CA  1 
ATOM 1958 C C   . VAL A 1 335 ? 150.499 153.211 111.084 1.00 128.68 ?  311  VAL Q C   1 
ATOM 1959 O O   . VAL A 1 335 ? 151.202 154.186 111.378 1.00 128.68 ?  311  VAL Q O   1 
ATOM 1960 C CB  . VAL A 1 335 ? 148.066 153.060 111.785 1.00 128.68 ?  311  VAL Q CB  1 
ATOM 1961 C CG1 . VAL A 1 335 ? 148.685 153.362 113.143 1.00 128.68 ?  311  VAL Q CG1 1 
ATOM 1962 C CG2 . VAL A 1 335 ? 146.767 153.830 111.602 1.00 128.68 ?  311  VAL Q CG2 1 
ATOM 1963 N N   . CYS A 1 336 ? 150.971 151.969 111.119 1.00 127.72 ?  312  CYS Q N   1 
ATOM 1964 C CA  . CYS A 1 336 ? 152.340 151.681 111.533 1.00 127.72 ?  312  CYS Q CA  1 
ATOM 1965 C C   . CYS A 1 336 ? 153.304 151.797 110.357 1.00 127.72 ?  312  CYS Q C   1 
ATOM 1966 O O   . CYS A 1 336 ? 153.680 150.797 109.745 1.00 127.72 ?  312  CYS Q O   1 
ATOM 1967 C CB  . CYS A 1 336 ? 152.430 150.285 112.154 1.00 127.72 ?  312  CYS Q CB  1 
ATOM 1968 S SG  . CYS A 1 336 ? 154.092 149.797 112.678 1.00 127.72 ?  312  CYS Q SG  1 
ATOM 1969 N N   . MET A 1 375 ? 139.296 118.814 100.324 1.00 99.59  ?  1001 MET Q N   1 
ATOM 1970 C CA  . MET A 1 375 ? 139.549 117.555 99.639  1.00 99.59  ?  1001 MET Q CA  1 
ATOM 1971 C C   . MET A 1 375 ? 139.832 117.924 98.189  1.00 99.59  ?  1001 MET Q C   1 
ATOM 1972 O O   . MET A 1 375 ? 140.546 117.220 97.470  1.00 99.59  ?  1001 MET Q O   1 
ATOM 1973 C CB  . MET A 1 375 ? 138.332 116.632 99.789  1.00 99.59  ?  1001 MET Q CB  1 
ATOM 1974 C CG  . MET A 1 375 ? 138.235 115.365 98.931  1.00 99.59  ?  1001 MET Q CG  1 
ATOM 1975 S SD  . MET A 1 375 ? 139.749 114.606 98.306  1.00 99.59  ?  1001 MET Q SD  1 
ATOM 1976 C CE  . MET A 1 375 ? 140.481 113.991 99.823  1.00 99.59  ?  1001 MET Q CE  1 
ATOM 1977 N N   . ILE A 1 376 ? 139.324 119.083 97.779  1.00 102.10 ?  1002 ILE Q N   1 
ATOM 1978 C CA  . ILE A 1 376 ? 139.454 119.574 96.415  1.00 102.10 ?  1002 ILE Q CA  1 
ATOM 1979 C C   . ILE A 1 376 ? 140.685 120.461 96.262  1.00 102.10 ?  1002 ILE Q C   1 
ATOM 1980 O O   . ILE A 1 376 ? 141.353 120.445 95.224  1.00 102.10 ?  1002 ILE Q O   1 
ATOM 1981 C CB  . ILE A 1 376 ? 138.179 120.320 95.973  1.00 102.10 ?  1002 ILE Q CB  1 
ATOM 1982 C CG1 . ILE A 1 376 ? 137.007 119.344 96.010  1.00 102.10 ?  1002 ILE Q CG1 1 
ATOM 1983 C CG2 . ILE A 1 376 ? 138.340 120.908 94.585  1.00 102.10 ?  1002 ILE Q CG2 1 
ATOM 1984 C CD1 . ILE A 1 376 ? 137.132 118.237 95.021  1.00 102.10 ?  1002 ILE Q CD1 1 
ATOM 1985 N N   . GLU A 1 377 ? 141.007 121.231 97.298  1.00 108.78 ?  1003 GLU Q N   1 
ATOM 1986 C CA  . GLU A 1 377 ? 142.171 122.107 97.313  1.00 108.78 ?  1003 GLU Q CA  1 
ATOM 1987 C C   . GLU A 1 377 ? 143.449 121.291 97.124  1.00 108.78 ?  1003 GLU Q C   1 
ATOM 1988 O O   . GLU A 1 377 ? 144.306 121.644 96.306  1.00 108.78 ?  1003 GLU Q O   1 
ATOM 1989 C CB  . GLU A 1 377 ? 142.173 122.895 98.631  1.00 108.78 ?  1003 GLU Q CB  1 
ATOM 1990 C CG  . GLU A 1 377 ? 143.510 123.341 99.231  1.00 108.78 ?  1003 GLU Q CG  1 
ATOM 1991 C CD  . GLU A 1 377 ? 144.458 123.984 98.238  1.00 108.78 ?  1003 GLU Q CD  1 
ATOM 1992 O OE1 . GLU A 1 377 ? 145.681 123.799 98.393  1.00 108.78 ?  1003 GLU Q OE1 1 
ATOM 1993 O OE2 . GLU A 1 377 ? 143.985 124.685 97.319  1.00 108.78 -1 1003 GLU Q OE2 1 
ATOM 1994 N N   . GLU A 1 378 ? 143.579 120.184 97.857  1.00 106.81 ?  1004 GLU Q N   1 
ATOM 1995 C CA  . GLU A 1 378 ? 144.742 119.316 97.702  1.00 106.81 ?  1004 GLU Q CA  1 
ATOM 1996 C C   . GLU A 1 378 ? 144.767 118.644 96.338  1.00 106.81 ?  1004 GLU Q C   1 
ATOM 1997 O O   . GLU A 1 378 ? 145.853 118.464 95.775  1.00 106.81 ?  1004 GLU Q O   1 
ATOM 1998 C CB  . GLU A 1 378 ? 144.766 118.309 98.874  1.00 106.81 ?  1004 GLU Q CB  1 
ATOM 1999 C CG  . GLU A 1 378 ? 145.871 117.210 98.959  1.00 106.81 ?  1004 GLU Q CG  1 
ATOM 2000 C CD  . GLU A 1 378 ? 146.019 116.274 97.763  1.00 106.81 ?  1004 GLU Q CD  1 
ATOM 2001 O OE1 . GLU A 1 378 ? 147.106 115.678 97.616  1.00 106.81 ?  1004 GLU Q OE1 1 
ATOM 2002 O OE2 . GLU A 1 378 ? 145.032 116.039 97.038  1.00 106.81 -1 1004 GLU Q OE2 1 
ATOM 2003 N N   . THR A 1 379 ? 143.608 118.262 95.798  1.00 102.28 ?  1005 THR Q N   1 
ATOM 2004 C CA  . THR A 1 379 ? 143.573 117.691 94.457  1.00 102.28 ?  1005 THR Q CA  1 
ATOM 2005 C C   . THR A 1 379 ? 144.081 118.691 93.429  1.00 102.28 ?  1005 THR Q C   1 
ATOM 2006 O O   . THR A 1 379 ? 144.848 118.334 92.527  1.00 102.28 ?  1005 THR Q O   1 
ATOM 2007 C CB  . THR A 1 379 ? 142.152 117.236 94.121  1.00 102.28 ?  1005 THR Q CB  1 
ATOM 2008 O OG1 . THR A 1 379 ? 141.902 115.962 94.726  1.00 102.28 ?  1005 THR Q OG1 1 
ATOM 2009 C CG2 . THR A 1 379 ? 141.959 117.121 92.618  1.00 102.28 ?  1005 THR Q CG2 1 
ATOM 2010 N N   . ALA A 1 380 ? 143.678 119.951 93.558  1.00 109.40 ?  1006 ALA Q N   1 
ATOM 2011 C CA  . ALA A 1 380 ? 144.190 121.022 92.719  1.00 109.40 ?  1006 ALA Q CA  1 
ATOM 2012 C C   . ALA A 1 380 ? 145.688 121.212 92.879  1.00 109.40 ?  1006 ALA Q C   1 
ATOM 2013 O O   . ALA A 1 380 ? 146.387 121.418 91.881  1.00 109.40 ?  1006 ALA Q O   1 
ATOM 2014 C CB  . ALA A 1 380 ? 143.464 122.333 93.033  1.00 109.40 ?  1006 ALA Q CB  1 
ATOM 2015 N N   . LYS A 1 381 ? 146.190 121.147 94.111  1.00 113.90 ?  1007 LYS Q N   1 
ATOM 2016 C CA  . LYS A 1 381 ? 147.629 121.191 94.343  1.00 113.90 ?  1007 LYS Q CA  1 
ATOM 2017 C C   . LYS A 1 381 ? 148.339 120.081 93.581  1.00 113.90 ?  1007 LYS Q C   1 
ATOM 2018 O O   . LYS A 1 381 ? 149.336 120.321 92.893  1.00 113.90 ?  1007 LYS Q O   1 
ATOM 2019 C CB  . LYS A 1 381 ? 147.927 121.071 95.838  1.00 113.90 ?  1007 LYS Q CB  1 
ATOM 2020 C CG  . LYS A 1 381 ? 147.664 122.327 96.633  1.00 113.90 ?  1007 LYS Q CG  1 
ATOM 2021 C CD  . LYS A 1 381 ? 148.880 123.235 96.658  1.00 113.90 ?  1007 LYS Q CD  1 
ATOM 2022 C CE  . LYS A 1 381 ? 149.014 123.922 98.007  1.00 113.90 ?  1007 LYS Q CE  1 
ATOM 2023 N NZ  . LYS A 1 381 ? 148.687 122.998 99.129  1.00 113.90 1  1007 LYS Q NZ  1 
ATOM 2024 N N   . LYS A 1 382 ? 147.835 118.854 93.703  1.00 116.01 ?  1008 LYS Q N   1 
ATOM 2025 C CA  . LYS A 1 382 ? 148.466 117.712 93.053  1.00 116.01 ?  1008 LYS Q CA  1 
ATOM 2026 C C   . LYS A 1 382 ? 148.447 117.862 91.535  1.00 116.01 ?  1008 LYS Q C   1 
ATOM 2027 O O   . LYS A 1 382 ? 149.439 117.578 90.854  1.00 116.01 ?  1008 LYS Q O   1 
ATOM 2028 C CB  . LYS A 1 382 ? 147.770 116.421 93.488  1.00 116.01 ?  1008 LYS Q CB  1 
ATOM 2029 C CG  . LYS A 1 382 ? 148.076 115.218 92.611  1.00 116.01 ?  1008 LYS Q CG  1 
ATOM 2030 C CD  . LYS A 1 382 ? 147.508 113.934 93.205  1.00 116.01 ?  1008 LYS Q CD  1 
ATOM 2031 C CE  . LYS A 1 382 ? 147.662 113.902 94.720  1.00 116.01 ?  1008 LYS Q CE  1 
ATOM 2032 N NZ  . LYS A 1 382 ? 146.967 112.739 95.337  1.00 116.01 1  1008 LYS Q NZ  1 
ATOM 2033 N N   . VAL A 1 383 ? 147.317 118.318 90.990  1.00 120.76 ?  1009 VAL Q N   1 
ATOM 2034 C CA  . VAL A 1 383 ? 147.214 118.516 89.547  1.00 120.76 ?  1009 VAL Q CA  1 
ATOM 2035 C C   . VAL A 1 383 ? 148.207 119.573 89.078  1.00 120.76 ?  1009 VAL Q C   1 
ATOM 2036 O O   . VAL A 1 383 ? 148.908 119.385 88.076  1.00 120.76 ?  1009 VAL Q O   1 
ATOM 2037 C CB  . VAL A 1 383 ? 145.769 118.884 89.160  1.00 120.76 ?  1009 VAL Q CB  1 
ATOM 2038 C CG1 . VAL A 1 383 ? 145.715 119.410 87.732  1.00 120.76 ?  1009 VAL Q CG1 1 
ATOM 2039 C CG2 . VAL A 1 383 ? 144.856 117.679 89.320  1.00 120.76 ?  1009 VAL Q CG2 1 
ATOM 2040 N N   . LYS A 1 384 ? 148.292 120.695 89.798  1.00 121.05 ?  1010 LYS Q N   1 
ATOM 2041 C CA  . LYS A 1 384 ? 149.201 121.761 89.392  1.00 121.05 ?  1010 LYS Q CA  1 
ATOM 2042 C C   . LYS A 1 384 ? 150.655 121.323 89.509  1.00 121.05 ?  1010 LYS Q C   1 
ATOM 2043 O O   . LYS A 1 384 ? 151.500 121.725 88.702  1.00 121.05 ?  1010 LYS Q O   1 
ATOM 2044 C CB  . LYS A 1 384 ? 148.949 123.017 90.226  1.00 121.05 ?  1010 LYS Q CB  1 
ATOM 2045 C CG  . LYS A 1 384 ? 149.722 124.234 89.750  1.00 121.05 ?  1010 LYS Q CG  1 
ATOM 2046 C CD  . LYS A 1 384 ? 149.506 124.477 88.267  1.00 121.05 ?  1010 LYS Q CD  1 
ATOM 2047 C CE  . LYS A 1 384 ? 150.125 125.792 87.825  1.00 121.05 ?  1010 LYS Q CE  1 
ATOM 2048 N NZ  . LYS A 1 384 ? 149.579 126.949 88.586  1.00 121.05 1  1010 LYS Q NZ  1 
ATOM 2049 N N   . GLU A 1 385 ? 150.966 120.501 90.512  1.00 124.12 ?  1011 GLU Q N   1 
ATOM 2050 C CA  . GLU A 1 385 ? 152.337 120.043 90.697  1.00 124.12 ?  1011 GLU Q CA  1 
ATOM 2051 C C   . GLU A 1 385 ? 152.779 119.073 89.610  1.00 124.12 ?  1011 GLU Q C   1 
ATOM 2052 O O   . GLU A 1 385 ? 153.983 118.939 89.371  1.00 124.12 ?  1011 GLU Q O   1 
ATOM 2053 C CB  . GLU A 1 385 ? 152.489 119.395 92.074  1.00 124.12 ?  1011 GLU Q CB  1 
ATOM 2054 C CG  . GLU A 1 385 ? 152.628 120.396 93.211  1.00 124.12 ?  1011 GLU Q CG  1 
ATOM 2055 C CD  . GLU A 1 385 ? 152.596 119.738 94.576  1.00 124.12 ?  1011 GLU Q CD  1 
ATOM 2056 O OE1 . GLU A 1 385 ? 153.430 118.843 94.826  1.00 124.12 ?  1011 GLU Q OE1 1 
ATOM 2057 O OE2 . GLU A 1 385 ? 151.736 120.117 95.399  1.00 124.12 -1 1011 GLU Q OE2 1 
ATOM 2058 N N   . LEU A 1 386 ? 151.841 118.401 88.945  1.00 127.10 ?  1012 LEU Q N   1 
ATOM 2059 C CA  . LEU A 1 386 ? 152.187 117.474 87.876  1.00 127.10 ?  1012 LEU Q CA  1 
ATOM 2060 C C   . LEU A 1 386 ? 152.426 118.168 86.544  1.00 127.10 ?  1012 LEU Q C   1 
ATOM 2061 O O   . LEU A 1 386 ? 152.786 117.496 85.572  1.00 127.10 ?  1012 LEU Q O   1 
ATOM 2062 C CB  . LEU A 1 386 ? 151.090 116.420 87.714  1.00 127.10 ?  1012 LEU Q CB  1 
ATOM 2063 C CG  . LEU A 1 386 ? 151.065 115.316 88.769  1.00 127.10 ?  1012 LEU Q CG  1 
ATOM 2064 C CD1 . LEU A 1 386 ? 149.912 114.360 88.515  1.00 127.10 ?  1012 LEU Q CD1 1 
ATOM 2065 C CD2 . LEU A 1 386 ? 152.387 114.570 88.780  1.00 127.10 ?  1012 LEU Q CD2 1 
ATOM 2066 N N   . GLY A 1 387 ? 152.235 119.483 86.472  1.00 134.30 ?  1013 GLY Q N   1 
ATOM 2067 C CA  . GLY A 1 387 ? 152.432 120.217 85.242  1.00 134.30 ?  1013 GLY Q CA  1 
ATOM 2068 C C   . GLY A 1 387 ? 151.277 120.164 84.268  1.00 134.30 ?  1013 GLY Q C   1 
ATOM 2069 O O   . GLY A 1 387 ? 151.372 120.764 83.190  1.00 134.30 ?  1013 GLY Q O   1 
ATOM 2070 N N   . PHE A 1 388 ? 150.192 119.472 84.605  1.00 137.89 ?  1014 PHE Q N   1 
ATOM 2071 C CA  . PHE A 1 388 ? 149.034 119.399 83.728  1.00 137.89 ?  1014 PHE Q CA  1 
ATOM 2072 C C   . PHE A 1 388 ? 148.274 120.718 83.761  1.00 137.89 ?  1014 PHE Q C   1 
ATOM 2073 O O   . PHE A 1 388 ? 147.912 121.210 84.834  1.00 137.89 ?  1014 PHE Q O   1 
ATOM 2074 C CB  . PHE A 1 388 ? 148.111 118.255 84.147  1.00 137.89 ?  1014 PHE Q CB  1 
ATOM 2075 C CG  . PHE A 1 388 ? 148.731 116.891 84.027  1.00 137.89 ?  1014 PHE Q CG  1 
ATOM 2076 C CD1 . PHE A 1 388 ? 149.764 116.655 83.138  1.00 137.89 ?  1014 PHE Q CD1 1 
ATOM 2077 C CD2 . PHE A 1 388 ? 148.267 115.839 84.799  1.00 137.89 ?  1014 PHE Q CD2 1 
ATOM 2078 C CE1 . PHE A 1 388 ? 150.327 115.399 83.028  1.00 137.89 ?  1014 PHE Q CE1 1 
ATOM 2079 C CE2 . PHE A 1 388 ? 148.826 114.582 84.692  1.00 137.89 ?  1014 PHE Q CE2 1 
ATOM 2080 C CZ  . PHE A 1 388 ? 149.856 114.362 83.806  1.00 137.89 ?  1014 PHE Q CZ  1 
ATOM 2081 N N   . LYS A 1 389 ? 148.034 121.291 82.583  1.00 138.10 ?  1015 LYS Q N   1 
ATOM 2082 C CA  . LYS A 1 389 ? 147.246 122.510 82.469  1.00 138.10 ?  1015 LYS Q CA  1 
ATOM 2083 C C   . LYS A 1 389 ? 145.800 122.255 82.070  1.00 138.10 ?  1015 LYS Q C   1 
ATOM 2084 O O   . LYS A 1 389 ? 145.037 123.215 81.928  1.00 138.10 ?  1015 LYS Q O   1 
ATOM 2085 C CB  . LYS A 1 389 ? 147.882 123.471 81.455  1.00 138.10 ?  1015 LYS Q CB  1 
ATOM 2086 C CG  . LYS A 1 389 ? 149.116 124.205 81.959  1.00 138.10 ?  1015 LYS Q CG  1 
ATOM 2087 C CD  . LYS A 1 389 ? 149.443 125.390 81.059  1.00 138.10 ?  1015 LYS Q CD  1 
ATOM 2088 C CE  . LYS A 1 389 ? 150.639 126.176 81.571  1.00 138.10 ?  1015 LYS Q CE  1 
ATOM 2089 N NZ  . LYS A 1 389 ? 150.865 127.415 80.775  1.00 138.10 1  1015 LYS Q NZ  1 
ATOM 2090 N N   . LYS A 1 390 ? 145.401 120.999 81.886  1.00 134.92 ?  1016 LYS Q N   1 
ATOM 2091 C CA  . LYS A 1 390 ? 144.065 120.715 81.381  1.00 134.92 ?  1016 LYS Q CA  1 
ATOM 2092 C C   . LYS A 1 390 ? 143.613 119.428 82.056  1.00 134.92 ?  1016 LYS Q C   1 
ATOM 2093 O O   . LYS A 1 390 ? 144.352 118.440 82.054  1.00 134.92 ?  1016 LYS Q O   1 
ATOM 2094 C CB  . LYS A 1 390 ? 144.104 120.586 79.842  1.00 134.92 ?  1016 LYS Q CB  1 
ATOM 2095 C CG  . LYS A 1 390 ? 143.138 119.636 79.076  1.00 134.92 ?  1016 LYS Q CG  1 
ATOM 2096 C CD  . LYS A 1 390 ? 141.717 119.546 79.630  1.00 134.92 ?  1016 LYS Q CD  1 
ATOM 2097 C CE  . LYS A 1 390 ? 141.132 120.949 79.800  1.00 134.92 ?  1016 LYS Q CE  1 
ATOM 2098 N NZ  . LYS A 1 390 ? 139.736 120.962 80.264  1.00 134.92 1  1016 LYS Q NZ  1 
ATOM 2099 N N   . ALA A 1 391 ? 142.412 119.435 82.633  1.00 138.12 ?  1017 ALA Q N   1 
ATOM 2100 C CA  . ALA A 1 391 ? 141.839 118.251 83.259  1.00 138.12 ?  1017 ALA Q CA  1 
ATOM 2101 C C   . ALA A 1 391 ? 140.418 118.037 82.759  1.00 138.12 ?  1017 ALA Q C   1 
ATOM 2102 O O   . ALA A 1 391 ? 139.701 119.000 82.479  1.00 138.12 ?  1017 ALA Q O   1 
ATOM 2103 C CB  . ALA A 1 391 ? 141.839 118.374 84.787  1.00 138.12 ?  1017 ALA Q CB  1 
ATOM 2104 N N   . GLY A 1 392 ? 140.019 116.772 82.640  1.00 142.68 ?  1018 GLY Q N   1 
ATOM 2105 C CA  . GLY A 1 392 ? 138.637 116.439 82.353  1.00 142.68 ?  1018 GLY Q CA  1 
ATOM 2106 C C   . GLY A 1 392 ? 137.930 115.935 83.599  1.00 142.68 ?  1018 GLY Q C   1 
ATOM 2107 O O   . GLY A 1 392 ? 138.554 115.393 84.505  1.00 142.68 ?  1018 GLY Q O   1 
ATOM 2108 N N   . LEU A 1 393 ? 136.611 116.119 83.644  1.00 131.24 ?  1019 LEU Q N   1 
ATOM 2109 C CA  . LEU A 1 393 ? 135.833 115.798 84.834  1.00 131.24 ?  1019 LEU Q CA  1 
ATOM 2110 C C   . LEU A 1 393 ? 134.700 114.833 84.518  1.00 131.24 ?  1019 LEU Q C   1 
ATOM 2111 O O   . LEU A 1 393 ? 134.043 114.950 83.480  1.00 131.24 ?  1019 LEU Q O   1 
ATOM 2112 C CB  . LEU A 1 393 ? 135.259 117.068 85.462  1.00 131.24 ?  1019 LEU Q CB  1 
ATOM 2113 C CG  . LEU A 1 393 ? 134.173 116.877 86.519  1.00 131.24 ?  1019 LEU Q CG  1 
ATOM 2114 C CD1 . LEU A 1 393 ? 134.695 116.079 87.700  1.00 131.24 ?  1019 LEU Q CD1 1 
ATOM 2115 C CD2 . LEU A 1 393 ? 133.649 118.224 86.967  1.00 131.24 ?  1019 LEU Q CD2 1 
ATOM 2116 N N   . LEU A 1 394 ? 134.471 113.884 85.426  1.00 122.86 ?  1020 LEU Q N   1 
ATOM 2117 C CA  . LEU A 1 394 ? 133.271 113.054 85.421  1.00 122.86 ?  1020 LEU Q CA  1 
ATOM 2118 C C   . LEU A 1 394 ? 132.642 113.146 86.804  1.00 122.86 ?  1020 LEU Q C   1 
ATOM 2119 O O   . LEU A 1 394 ? 133.215 112.654 87.780  1.00 122.86 ?  1020 LEU Q O   1 
ATOM 2120 C CB  . LEU A 1 394 ? 133.599 111.604 85.070  1.00 122.86 ?  1020 LEU Q CB  1 
ATOM 2121 C CG  . LEU A 1 394 ? 134.785 111.329 84.143  1.00 122.86 ?  1020 LEU Q CG  1 
ATOM 2122 C CD1 . LEU A 1 394 ? 135.066 109.839 84.076  1.00 122.86 ?  1020 LEU Q CD1 1 
ATOM 2123 C CD2 . LEU A 1 394 ? 134.506 111.866 82.751  1.00 122.86 ?  1020 LEU Q CD2 1 
ATOM 2124 N N   . ALA A 1 395 ? 131.470 113.771 86.894  1.00 118.57 ?  1021 ALA Q N   1 
ATOM 2125 C CA  . ALA A 1 395 ? 130.778 113.917 88.167  1.00 118.57 ?  1021 ALA Q CA  1 
ATOM 2126 C C   . ALA A 1 395 ? 129.295 114.150 87.904  1.00 118.57 ?  1021 ALA Q C   1 
ATOM 2127 O O   . ALA A 1 395 ? 128.835 114.136 86.759  1.00 118.57 ?  1021 ALA Q O   1 
ATOM 2128 C CB  . ALA A 1 395 ? 131.381 115.052 88.998  1.00 118.57 ?  1021 ALA Q CB  1 
ATOM 2129 N N   . THR A 1 396 ? 128.545 114.366 88.982  1.00 112.49 ?  1022 THR Q N   1 
ATOM 2130 C CA  . THR A 1 396 ? 127.106 114.562 88.887  1.00 112.49 ?  1022 THR Q CA  1 
ATOM 2131 C C   . THR A 1 396 ? 126.779 115.938 88.316  1.00 112.49 ?  1022 THR Q C   1 
ATOM 2132 O O   . THR A 1 396 ? 127.596 116.863 88.341  1.00 112.49 ?  1022 THR Q O   1 
ATOM 2133 C CB  . THR A 1 396 ? 126.445 114.405 90.256  1.00 112.49 ?  1022 THR Q CB  1 
ATOM 2134 O OG1 . THR A 1 396 ? 126.911 115.439 91.131  1.00 112.49 ?  1022 THR Q OG1 1 
ATOM 2135 C CG2 . THR A 1 396 ? 126.783 113.050 90.858  1.00 112.49 ?  1022 THR Q CG2 1 
ATOM 2136 N N   . THR A 1 397 ? 125.554 116.064 87.800  1.00 108.93 ?  1023 THR Q N   1 
ATOM 2137 C CA  . THR A 1 397 ? 125.120 117.327 87.212  1.00 108.93 ?  1023 THR Q CA  1 
ATOM 2138 C C   . THR A 1 397 ? 125.095 118.441 88.251  1.00 108.93 ?  1023 THR Q C   1 
ATOM 2139 O O   . THR A 1 397 ? 125.488 119.581 87.967  1.00 108.93 ?  1023 THR Q O   1 
ATOM 2140 C CB  . THR A 1 397 ? 123.743 117.163 86.572  1.00 108.93 ?  1023 THR Q CB  1 
ATOM 2141 O OG1 . THR A 1 397 ? 122.938 116.301 87.386  1.00 108.93 ?  1023 THR Q OG1 1 
ATOM 2142 C CG2 . THR A 1 397 ? 123.872 116.563 85.181  1.00 108.93 ?  1023 THR Q CG2 1 
ATOM 2143 N N   . GLY A 1 398 ? 124.627 118.133 89.459  1.00 108.49 ?  1024 GLY Q N   1 
ATOM 2144 C CA  . GLY A 1 398 ? 124.639 119.132 90.511  1.00 108.49 ?  1024 GLY Q CA  1 
ATOM 2145 C C   . GLY A 1 398 ? 126.036 119.634 90.807  1.00 108.49 ?  1024 GLY Q C   1 
ATOM 2146 O O   . GLY A 1 398 ? 126.245 120.830 91.017  1.00 108.49 ?  1024 GLY Q O   1 
ATOM 2147 N N   . THR A 1 399 ? 127.015 118.728 90.816  1.00 112.51 ?  1025 THR Q N   1 
ATOM 2148 C CA  . THR A 1 399 ? 128.384 119.121 91.128  1.00 112.51 ?  1025 THR Q CA  1 
ATOM 2149 C C   . THR A 1 399 ? 128.941 120.071 90.077  1.00 112.51 ?  1025 THR Q C   1 
ATOM 2150 O O   . THR A 1 399 ? 129.562 121.086 90.412  1.00 112.51 ?  1025 THR Q O   1 
ATOM 2151 C CB  . THR A 1 399 ? 129.268 117.882 91.261  1.00 112.51 ?  1025 THR Q CB  1 
ATOM 2152 O OG1 . THR A 1 399 ? 128.923 116.936 90.244  1.00 112.51 ?  1025 THR Q OG1 1 
ATOM 2153 C CG2 . THR A 1 399 ? 129.086 117.245 92.630  1.00 112.51 ?  1025 THR Q CG2 1 
ATOM 2154 N N   . ILE A 1 400 ? 128.728 119.765 88.796  1.00 110.59 ?  1026 ILE Q N   1 
ATOM 2155 C CA  . ILE A 1 400 ? 129.267 120.632 87.753  1.00 110.59 ?  1026 ILE Q CA  1 
ATOM 2156 C C   . ILE A 1 400 ? 128.553 121.974 87.764  1.00 110.59 ?  1026 ILE Q C   1 
ATOM 2157 O O   . ILE A 1 400 ? 129.175 123.025 87.568  1.00 110.59 ?  1026 ILE Q O   1 
ATOM 2158 C CB  . ILE A 1 400 ? 129.176 119.963 86.372  1.00 110.59 ?  1026 ILE Q CB  1 
ATOM 2159 C CG1 . ILE A 1 400 ? 127.871 119.197 86.228  1.00 110.59 ?  1026 ILE Q CG1 1 
ATOM 2160 C CG2 . ILE A 1 400 ? 130.327 119.010 86.175  1.00 110.59 ?  1026 ILE Q CG2 1 
ATOM 2161 C CD1 . ILE A 1 400 ? 127.753 118.435 84.939  1.00 110.59 ?  1026 ILE Q CD1 1 
ATOM 2162 N N   . VAL A 1 401 ? 127.239 121.964 87.990  1.00 113.92 ?  1027 VAL Q N   1 
ATOM 2163 C CA  . VAL A 1 401 ? 126.499 123.219 88.035  1.00 113.92 ?  1027 VAL Q CA  1 
ATOM 2164 C C   . VAL A 1 401 ? 126.951 124.062 89.221  1.00 113.92 ?  1027 VAL Q C   1 
ATOM 2165 O O   . VAL A 1 401 ? 127.013 125.294 89.136  1.00 113.92 ?  1027 VAL Q O   1 
ATOM 2166 C CB  . VAL A 1 401 ? 124.986 122.938 88.064  1.00 113.92 ?  1027 VAL Q CB  1 
ATOM 2167 C CG1 . VAL A 1 401 ? 124.205 124.196 88.417  1.00 113.92 ?  1027 VAL Q CG1 1 
ATOM 2168 C CG2 . VAL A 1 401 ? 124.538 122.389 86.721  1.00 113.92 ?  1027 VAL Q CG2 1 
ATOM 2169 N N   . SER A 1 402 ? 127.300 123.410 90.335  1.00 109.33 ?  1028 SER Q N   1 
ATOM 2170 C CA  . SER A 1 402 ? 127.642 124.122 91.561  1.00 109.33 ?  1028 SER Q CA  1 
ATOM 2171 C C   . SER A 1 402 ? 128.800 125.089 91.374  1.00 109.33 ?  1028 SER Q C   1 
ATOM 2172 O O   . SER A 1 402 ? 128.896 126.074 92.113  1.00 109.33 ?  1028 SER Q O   1 
ATOM 2173 C CB  . SER A 1 402 ? 127.980 123.124 92.666  1.00 109.33 ?  1028 SER Q CB  1 
ATOM 2174 O OG  . SER A 1 402 ? 129.154 122.400 92.347  1.00 109.33 ?  1028 SER Q OG  1 
ATOM 2175 N N   . GLY A 1 403 ? 129.679 124.835 90.411  1.00 111.07 ?  1029 GLY Q N   1 
ATOM 2176 C CA  . GLY A 1 403 ? 130.748 125.757 90.110  1.00 111.07 ?  1029 GLY Q CA  1 
ATOM 2177 C C   . GLY A 1 403 ? 131.961 125.670 91.008  1.00 111.07 ?  1029 GLY Q C   1 
ATOM 2178 O O   . GLY A 1 403 ? 132.887 126.470 90.837  1.00 111.07 ?  1029 GLY Q O   1 
ATOM 2179 N N   . VAL A 1 404 ? 132.001 124.720 91.945  1.00 110.95 ?  1030 VAL Q N   1 
ATOM 2180 C CA  . VAL A 1 404 ? 133.130 124.635 92.868  1.00 110.95 ?  1030 VAL Q CA  1 
ATOM 2181 C C   . VAL A 1 404 ? 134.417 124.296 92.126  1.00 110.95 ?  1030 VAL Q C   1 
ATOM 2182 O O   . VAL A 1 404 ? 135.467 124.913 92.359  1.00 110.95 ?  1030 VAL Q O   1 
ATOM 2183 C CB  . VAL A 1 404 ? 132.830 123.615 93.982  1.00 110.95 ?  1030 VAL Q CB  1 
ATOM 2184 C CG1 . VAL A 1 404 ? 131.842 124.196 94.973  1.00 110.95 ?  1030 VAL Q CG1 1 
ATOM 2185 C CG2 . VAL A 1 404 ? 132.279 122.330 93.391  1.00 110.95 ?  1030 VAL Q CG2 1 
ATOM 2186 N N   . TYR A 1 405 ? 134.359 123.316 91.220  1.00 113.56 ?  1031 TYR Q N   1 
ATOM 2187 C CA  . TYR A 1 405 ? 135.579 122.818 90.596  1.00 113.56 ?  1031 TYR Q CA  1 
ATOM 2188 C C   . TYR A 1 405 ? 136.257 123.899 89.772  1.00 113.56 ?  1031 TYR Q C   1 
ATOM 2189 O O   . TYR A 1 405 ? 137.487 124.021 89.784  1.00 113.56 ?  1031 TYR Q O   1 
ATOM 2190 C CB  . TYR A 1 405 ? 135.272 121.611 89.715  1.00 113.56 ?  1031 TYR Q CB  1 
ATOM 2191 C CG  . TYR A 1 405 ? 135.310 120.305 90.452  1.00 113.56 ?  1031 TYR Q CG  1 
ATOM 2192 C CD1 . TYR A 1 405 ? 135.266 120.272 91.831  1.00 113.56 ?  1031 TYR Q CD1 1 
ATOM 2193 C CD2 . TYR A 1 405 ? 135.332 119.104 89.772  1.00 113.56 ?  1031 TYR Q CD2 1 
ATOM 2194 C CE1 . TYR A 1 405 ? 135.273 119.083 92.508  1.00 113.56 ?  1031 TYR Q CE1 1 
ATOM 2195 C CE2 . TYR A 1 405 ? 135.353 117.906 90.445  1.00 113.56 ?  1031 TYR Q CE2 1 
ATOM 2196 C CZ  . TYR A 1 405 ? 135.323 117.899 91.814  1.00 113.56 ?  1031 TYR Q CZ  1 
ATOM 2197 O OH  . TYR A 1 405 ? 135.336 116.701 92.492  1.00 113.56 ?  1031 TYR Q OH  1 
ATOM 2198 N N   . GLU A 1 406 ? 135.469 124.686 89.041  1.00 115.57 ?  1032 GLU Q N   1 
ATOM 2199 C CA  . GLU A 1 406 ? 136.032 125.728 88.191  1.00 115.57 ?  1032 GLU Q CA  1 
ATOM 2200 C C   . GLU A 1 406 ? 136.811 126.755 89.003  1.00 115.57 ?  1032 GLU Q C   1 
ATOM 2201 O O   . GLU A 1 406 ? 137.956 127.072 88.670  1.00 115.57 ?  1032 GLU Q O   1 
ATOM 2202 C CB  . GLU A 1 406 ? 134.927 126.391 87.360  1.00 115.57 ?  1032 GLU Q CB  1 
ATOM 2203 C CG  . GLU A 1 406 ? 133.926 125.450 86.636  1.00 115.57 ?  1032 GLU Q CG  1 
ATOM 2204 C CD  . GLU A 1 406 ? 133.055 124.587 87.535  1.00 115.57 ?  1032 GLU Q CD  1 
ATOM 2205 O OE1 . GLU A 1 406 ? 133.284 124.560 88.757  1.00 115.57 ?  1032 GLU Q OE1 1 
ATOM 2206 O OE2 . GLU A 1 406 ? 132.135 123.927 87.009  1.00 115.57 -1 1032 GLU Q OE2 1 
ATOM 2207 N N   . LYS A 1 407 ? 136.222 127.279 90.081  1.00 115.52 ?  1033 LYS Q N   1 
ATOM 2208 C CA  . LYS A 1 407 ? 136.964 128.246 90.886  1.00 115.52 ?  1033 LYS Q CA  1 
ATOM 2209 C C   . LYS A 1 407 ? 138.177 127.604 91.543  1.00 115.52 ?  1033 LYS Q C   1 
ATOM 2210 O O   . LYS A 1 407 ? 139.266 128.194 91.557  1.00 115.52 ?  1033 LYS Q O   1 
ATOM 2211 C CB  . LYS A 1 407 ? 136.073 128.890 91.950  1.00 115.52 ?  1033 LYS Q CB  1 
ATOM 2212 C CG  . LYS A 1 407 ? 134.903 128.060 92.422  1.00 115.52 ?  1033 LYS Q CG  1 
ATOM 2213 C CD  . LYS A 1 407 ? 133.922 128.922 93.205  1.00 115.52 ?  1033 LYS Q CD  1 
ATOM 2214 C CE  . LYS A 1 407 ? 132.931 129.625 92.294  1.00 115.52 ?  1033 LYS Q CE  1 
ATOM 2215 N NZ  . LYS A 1 407 ? 132.222 128.685 91.389  1.00 115.52 1  1033 LYS Q NZ  1 
ATOM 2216 N N   . GLU A 1 408 ? 138.016 126.395 92.086  1.00 117.08 ?  1034 GLU Q N   1 
ATOM 2217 C CA  . GLU A 1 408 ? 139.124 125.767 92.798  1.00 117.08 ?  1034 GLU Q CA  1 
ATOM 2218 C C   . GLU A 1 408 ? 140.307 125.513 91.873  1.00 117.08 ?  1034 GLU Q C   1 
ATOM 2219 O O   . GLU A 1 408 ? 141.462 125.736 92.255  1.00 117.08 ?  1034 GLU Q O   1 
ATOM 2220 C CB  . GLU A 1 408 ? 138.665 124.466 93.456  1.00 117.08 ?  1034 GLU Q CB  1 
ATOM 2221 C CG  . GLU A 1 408 ? 137.707 124.675 94.613  1.00 117.08 ?  1034 GLU Q CG  1 
ATOM 2222 C CD  . GLU A 1 408 ? 138.230 125.678 95.620  1.00 117.08 ?  1034 GLU Q CD  1 
ATOM 2223 O OE1 . GLU A 1 408 ? 139.410 125.568 96.018  1.00 117.08 ?  1034 GLU Q OE1 1 
ATOM 2224 O OE2 . GLU A 1 408 ? 137.463 126.581 96.016  1.00 117.08 -1 1034 GLU Q OE2 1 
ATOM 2225 N N   . PHE A 1 409 ? 140.041 125.051 90.652  1.00 120.85 ?  1035 PHE Q N   1 
ATOM 2226 C CA  . PHE A 1 409 ? 141.119 124.763 89.717  1.00 120.85 ?  1035 PHE Q CA  1 
ATOM 2227 C C   . PHE A 1 409 ? 141.611 126.014 89.003  1.00 120.85 ?  1035 PHE Q C   1 
ATOM 2228 O O   . PHE A 1 409 ? 142.736 126.026 88.492  1.00 120.85 ?  1035 PHE Q O   1 
ATOM 2229 C CB  . PHE A 1 409 ? 140.652 123.712 88.713  1.00 120.85 ?  1035 PHE Q CB  1 
ATOM 2230 C CG  . PHE A 1 409 ? 140.600 122.325 89.278  1.00 120.85 ?  1035 PHE Q CG  1 
ATOM 2231 C CD1 . PHE A 1 409 ? 141.658 121.822 90.010  1.00 120.85 ?  1035 PHE Q CD1 1 
ATOM 2232 C CD2 . PHE A 1 409 ? 139.476 121.537 89.112  1.00 120.85 ?  1035 PHE Q CD2 1 
ATOM 2233 C CE1 . PHE A 1 409 ? 141.608 120.546 90.535  1.00 120.85 ?  1035 PHE Q CE1 1 
ATOM 2234 C CE2 . PHE A 1 409 ? 139.418 120.261 89.637  1.00 120.85 ?  1035 PHE Q CE2 1 
ATOM 2235 C CZ  . PHE A 1 409 ? 140.486 119.766 90.352  1.00 120.85 ?  1035 PHE Q CZ  1 
ATOM 2236 N N   . SER A 1 410 ? 140.797 127.072 88.956  1.00 117.33 ?  1036 SER Q N   1 
ATOM 2237 C CA  . SER A 1 410 ? 141.262 128.334 88.397  1.00 117.33 ?  1036 SER Q CA  1 
ATOM 2238 C C   . SER A 1 410 ? 142.155 129.076 89.376  1.00 117.33 ?  1036 SER Q C   1 
ATOM 2239 O O   . SER A 1 410 ? 142.986 129.892 88.959  1.00 117.33 ?  1036 SER Q O   1 
ATOM 2240 C CB  . SER A 1 410 ? 140.069 129.202 87.999  1.00 117.33 ?  1036 SER Q CB  1 
ATOM 2241 O OG  . SER A 1 410 ? 139.347 129.625 89.142  1.00 117.33 ?  1036 SER Q OG  1 
ATOM 2242 N N   . LYS A 1 411 ? 141.993 128.817 90.676  1.00 116.59 ?  1037 LYS Q N   1 
ATOM 2243 C CA  . LYS A 1 411 ? 142.892 129.404 91.662  1.00 116.59 ?  1037 LYS Q CA  1 
ATOM 2244 C C   . LYS A 1 411 ? 144.344 129.020 91.411  1.00 116.59 ?  1037 LYS Q C   1 
ATOM 2245 O O   . LYS A 1 411 ? 145.249 129.769 91.796  1.00 116.59 ?  1037 LYS Q O   1 
ATOM 2246 C CB  . LYS A 1 411 ? 142.480 128.981 93.073  1.00 116.59 ?  1037 LYS Q CB  1 
ATOM 2247 C CG  . LYS A 1 411 ? 141.228 129.669 93.592  1.00 116.59 ?  1037 LYS Q CG  1 
ATOM 2248 C CD  . LYS A 1 411 ? 140.869 129.184 94.987  1.00 116.59 ?  1037 LYS Q CD  1 
ATOM 2249 C CE  . LYS A 1 411 ? 139.567 129.802 95.469  1.00 116.59 ?  1037 LYS Q CE  1 
ATOM 2250 N NZ  . LYS A 1 411 ? 139.167 129.286 96.807  1.00 116.59 1  1037 LYS Q NZ  1 
ATOM 2251 N N   . TYR A 1 412 ? 144.585 127.875 90.775  1.00 121.21 ?  1038 TYR Q N   1 
ATOM 2252 C CA  . TYR A 1 412 ? 145.926 127.443 90.409  1.00 121.21 ?  1038 TYR Q CA  1 
ATOM 2253 C C   . TYR A 1 412 ? 146.169 127.513 88.906  1.00 121.21 ?  1038 TYR Q C   1 
ATOM 2254 O O   . TYR A 1 412 ? 147.221 127.066 88.437  1.00 121.21 ?  1038 TYR Q O   1 
ATOM 2255 C CB  . TYR A 1 412 ? 146.177 126.021 90.914  1.00 121.21 ?  1038 TYR Q CB  1 
ATOM 2256 C CG  . TYR A 1 412 ? 146.285 125.917 92.418  1.00 121.21 ?  1038 TYR Q CG  1 
ATOM 2257 C CD1 . TYR A 1 412 ? 147.505 126.078 93.059  1.00 121.21 ?  1038 TYR Q CD1 1 
ATOM 2258 C CD2 . TYR A 1 412 ? 145.166 125.661 93.196  1.00 121.21 ?  1038 TYR Q CD2 1 
ATOM 2259 C CE1 . TYR A 1 412 ? 147.607 125.984 94.433  1.00 121.21 ?  1038 TYR Q CE1 1 
ATOM 2260 C CE2 . TYR A 1 412 ? 145.257 125.565 94.569  1.00 121.21 ?  1038 TYR Q CE2 1 
ATOM 2261 C CZ  . TYR A 1 412 ? 146.479 125.728 95.183  1.00 121.21 ?  1038 TYR Q CZ  1 
ATOM 2262 O OH  . TYR A 1 412 ? 146.573 125.633 96.552  1.00 121.21 ?  1038 TYR Q OH  1 
ATOM 2263 N N   . GLY A 1 413 ? 145.227 128.063 88.143  1.00 129.31 ?  1039 GLY Q N   1 
ATOM 2264 C CA  . GLY A 1 413 ? 145.395 128.169 86.707  1.00 129.31 ?  1039 GLY Q CA  1 
ATOM 2265 C C   . GLY A 1 413 ? 145.185 126.892 85.927  1.00 129.31 ?  1039 GLY Q C   1 
ATOM 2266 O O   . GLY A 1 413 ? 145.833 126.701 84.893  1.00 129.31 ?  1039 GLY Q O   1 
ATOM 2267 N N   . VAL A 1 414 ? 144.300 126.008 86.384  1.00 133.30 ?  1040 VAL Q N   1 
ATOM 2268 C CA  . VAL A 1 414 ? 144.011 124.747 85.711  1.00 133.30 ?  1040 VAL Q CA  1 
ATOM 2269 C C   . VAL A 1 414 ? 142.598 124.813 85.147  1.00 133.30 ?  1040 VAL Q C   1 
ATOM 2270 O O   . VAL A 1 414 ? 141.668 125.250 85.836  1.00 133.30 ?  1040 VAL Q O   1 
ATOM 2271 C CB  . VAL A 1 414 ? 144.169 123.548 86.662  1.00 133.30 ?  1040 VAL Q CB  1 
ATOM 2272 C CG1 . VAL A 1 414 ? 144.075 122.243 85.887  1.00 133.30 ?  1040 VAL Q CG1 1 
ATOM 2273 C CG2 . VAL A 1 414 ? 145.489 123.636 87.411  1.00 133.30 ?  1040 VAL Q CG2 1 
ATOM 2274 N N   . GLU A 1 415 ? 142.439 124.381 83.900  1.00 134.92 ?  1041 GLU Q N   1 
ATOM 2275 C CA  . GLU A 1 415 ? 141.160 124.428 83.206  1.00 134.92 ?  1041 GLU Q CA  1 
ATOM 2276 C C   . GLU A 1 415 ? 140.538 123.039 83.146  1.00 134.92 ?  1041 GLU Q C   1 
ATOM 2277 O O   . GLU A 1 415 ? 141.211 122.061 82.807  1.00 134.92 ?  1041 GLU Q O   1 
ATOM 2278 C CB  . GLU A 1 415 ? 141.330 124.985 81.791  1.00 134.92 ?  1041 GLU Q CB  1 
ATOM 2279 C CG  . GLU A 1 415 ? 140.124 124.770 80.889  1.00 134.92 ?  1041 GLU Q CG  1 
ATOM 2280 C CD  . GLU A 1 415 ? 140.405 125.125 79.444  1.00 134.92 ?  1041 GLU Q CD  1 
ATOM 2281 O OE1 . GLU A 1 415 ? 140.568 126.327 79.146  1.00 134.92 ?  1041 GLU Q OE1 1 
ATOM 2282 O OE2 . GLU A 1 415 ? 140.463 124.202 78.604  1.00 134.92 -1 1041 GLU Q OE2 1 
ATOM 2283 N N   . ILE A 1 416 ? 139.247 122.964 83.464  1.00 122.60 ?  1042 ILE Q N   1 
ATOM 2284 C CA  . ILE A 1 416 ? 138.512 121.707 83.503  1.00 122.60 ?  1042 ILE Q CA  1 
ATOM 2285 C C   . ILE A 1 416 ? 137.572 121.637 82.310  1.00 122.60 ?  1042 ILE Q C   1 
ATOM 2286 O O   . ILE A 1 416 ? 137.137 122.659 81.765  1.00 122.60 ?  1042 ILE Q O   1 
ATOM 2287 C CB  . ILE A 1 416 ? 137.728 121.547 84.819  1.00 122.60 ?  1042 ILE Q CB  1 
ATOM 2288 C CG1 . ILE A 1 416 ? 136.351 122.203 84.709  1.00 122.60 ?  1042 ILE Q CG1 1 
ATOM 2289 C CG2 . ILE A 1 416 ? 138.500 122.171 85.955  1.00 122.60 ?  1042 ILE Q CG2 1 
ATOM 2290 C CD1 . ILE A 1 416 ? 135.572 122.210 86.004  1.00 122.60 ?  1042 ILE Q CD1 1 
ATOM 2291 N N   . MET A 1 417 ? 137.273 120.412 81.892  1.00 129.53 ?  1043 MET Q N   1 
ATOM 2292 C CA  . MET A 1 417 ? 136.373 120.164 80.777  1.00 129.53 ?  1043 MET Q CA  1 
ATOM 2293 C C   . MET A 1 417 ? 135.263 119.226 81.219  1.00 129.53 ?  1043 MET Q C   1 
ATOM 2294 O O   . MET A 1 417 ? 135.527 118.169 81.808  1.00 129.53 ?  1043 MET Q O   1 
ATOM 2295 C CB  . MET A 1 417 ? 137.106 119.558 79.576  1.00 129.53 ?  1043 MET Q CB  1 
ATOM 2296 C CG  . MET A 1 417 ? 136.270 119.361 78.302  1.00 129.53 ?  1043 MET Q CG  1 
ATOM 2297 S SD  . MET A 1 417 ? 134.805 120.384 77.976  1.00 129.53 ?  1043 MET Q SD  1 
ATOM 2298 C CE  . MET A 1 417 ? 135.368 122.069 78.252  1.00 129.53 ?  1043 MET Q CE  1 
ATOM 2299 N N   . THR A 1 418 ? 134.042 119.609 80.921  1.00 130.65 ?  1044 THR Q N   1 
ATOM 2300 C CA  . THR A 1 418 ? 132.876 118.780 81.114  1.00 130.65 ?  1044 THR Q CA  1 
ATOM 2301 C C   . THR A 1 418 ? 132.215 118.511 79.772  1.00 130.65 ?  1044 THR Q C   1 
ATOM 2302 O O   . THR A 1 418 ? 132.057 119.435 78.967  1.00 130.65 ?  1044 THR Q O   1 
ATOM 2303 C CB  . THR A 1 418 ? 131.866 119.452 82.049  1.00 130.65 ?  1044 THR Q CB  1 
ATOM 2304 O OG1 . THR A 1 418 ? 131.483 120.721 81.506  1.00 130.65 ?  1044 THR Q OG1 1 
ATOM 2305 C CG2 . THR A 1 418 ? 132.486 119.669 83.416  1.00 130.65 ?  1044 THR Q CG2 1 
ATOM 2306 N N   . PRO A 1 419 ? 131.820 117.274 79.500  1.00 131.01 ?  1045 PRO Q N   1 
ATOM 2307 C CA  . PRO A 1 419 ? 131.208 116.959 78.203  1.00 131.01 ?  1045 PRO Q CA  1 
ATOM 2308 C C   . PRO A 1 419 ? 129.886 117.691 78.007  1.00 131.01 ?  1045 PRO Q C   1 
ATOM 2309 O O   . PRO A 1 419 ? 129.396 118.414 78.875  1.00 131.01 ?  1045 PRO Q O   1 
ATOM 2310 C CB  . PRO A 1 419 ? 131.012 115.440 78.240  1.00 131.01 ?  1045 PRO Q CB  1 
ATOM 2311 C CG  . PRO A 1 419 ? 131.670 114.952 79.481  1.00 131.01 ?  1045 PRO Q CG  1 
ATOM 2312 C CD  . PRO A 1 419 ? 131.956 116.101 80.378  1.00 131.01 ?  1045 PRO Q CD  1 
ATOM 2313 N N   . THR A 1 420 ? 129.315 117.508 76.819  1.00 126.33 ?  1046 THR Q N   1 
ATOM 2314 C CA  . THR A 1 420 ? 128.082 118.198 76.479  1.00 126.33 ?  1046 THR Q CA  1 
ATOM 2315 C C   . THR A 1 420 ? 126.916 117.634 77.286  1.00 126.33 ?  1046 THR Q C   1 
ATOM 2316 O O   . THR A 1 420 ? 127.011 116.578 77.917  1.00 126.33 ?  1046 THR Q O   1 
ATOM 2317 C CB  . THR A 1 420 ? 127.794 118.085 74.984  1.00 126.33 ?  1046 THR Q CB  1 
ATOM 2318 O OG1 . THR A 1 420 ? 127.496 116.723 74.658  1.00 126.33 ?  1046 THR Q OG1 1 
ATOM 2319 C CG2 . THR A 1 420 ? 129.000 118.542 74.176  1.00 126.33 ?  1046 THR Q CG2 1 
ATOM 2320 N N   . GLU A 1 421 ? 125.796 118.359 77.249  1.00 127.58 ?  1047 GLU Q N   1 
ATOM 2321 C CA  . GLU A 1 421 ? 124.664 118.015 78.104  1.00 127.58 ?  1047 GLU Q CA  1 
ATOM 2322 C C   . GLU A 1 421 ? 124.130 116.618 77.805  1.00 127.58 ?  1047 GLU Q C   1 
ATOM 2323 O O   . GLU A 1 421 ? 123.641 115.930 78.708  1.00 127.58 ?  1047 GLU Q O   1 
ATOM 2324 C CB  . GLU A 1 421 ? 123.567 119.079 77.979  1.00 127.58 ?  1047 GLU Q CB  1 
ATOM 2325 C CG  . GLU A 1 421 ? 122.569 118.967 76.808  1.00 127.58 ?  1047 GLU Q CG  1 
ATOM 2326 C CD  . GLU A 1 421 ? 123.193 118.633 75.455  1.00 127.58 ?  1047 GLU Q CD  1 
ATOM 2327 O OE1 . GLU A 1 421 ? 122.437 118.224 74.549  1.00 127.58 ?  1047 GLU Q OE1 1 
ATOM 2328 O OE2 . GLU A 1 421 ? 124.414 118.822 75.271  1.00 127.58 -1 1047 GLU Q OE2 1 
ATOM 2329 N N   . ASP A 1 422 ? 124.219 116.174 76.551  1.00 132.81 ?  1048 ASP Q N   1 
ATOM 2330 C CA  . ASP A 1 422 ? 123.802 114.814 76.236  1.00 132.81 ?  1048 ASP Q CA  1 
ATOM 2331 C C   . ASP A 1 422 ? 124.713 113.800 76.910  1.00 132.81 ?  1048 ASP Q C   1 
ATOM 2332 O O   . ASP A 1 422 ? 124.244 112.823 77.504  1.00 132.81 ?  1048 ASP Q O   1 
ATOM 2333 C CB  . ASP A 1 422 ? 123.782 114.601 74.723  1.00 132.81 ?  1048 ASP Q CB  1 
ATOM 2334 C CG  . ASP A 1 422 ? 122.976 113.382 74.319  1.00 132.81 ?  1048 ASP Q CG  1 
ATOM 2335 O OD1 . ASP A 1 422 ? 121.741 113.396 74.508  1.00 132.81 ?  1048 ASP Q OD1 1 
ATOM 2336 O OD2 . ASP A 1 422 ? 123.574 112.410 73.813  1.00 132.81 -1 1048 ASP Q OD2 1 
ATOM 2337 N N   . GLU A 1 423 ? 126.023 114.028 76.851  1.00 134.74 ?  1049 GLU Q N   1 
ATOM 2338 C CA  . GLU A 1 423 ? 126.939 113.156 77.570  1.00 134.74 ?  1049 GLU Q CA  1 
ATOM 2339 C C   . GLU A 1 423 ? 126.860 113.361 79.076  1.00 134.74 ?  1049 GLU Q C   1 
ATOM 2340 O O   . GLU A 1 423 ? 127.155 112.427 79.829  1.00 134.74 ?  1049 GLU Q O   1 
ATOM 2341 C CB  . GLU A 1 423 ? 128.362 113.355 77.049  1.00 134.74 ?  1049 GLU Q CB  1 
ATOM 2342 C CG  . GLU A 1 423 ? 128.410 113.779 75.585  1.00 134.74 ?  1049 GLU Q CG  1 
ATOM 2343 C CD  . GLU A 1 423 ? 129.736 114.389 75.179  1.00 134.74 ?  1049 GLU Q CD  1 
ATOM 2344 O OE1 . GLU A 1 423 ? 129.905 115.616 75.336  1.00 134.74 ?  1049 GLU Q OE1 1 
ATOM 2345 O OE2 . GLU A 1 423 ? 130.610 113.640 74.692  1.00 134.74 -1 1049 GLU Q OE2 1 
ATOM 2346 N N   . GLN A 1 424 ? 126.445 114.543 79.537  1.00 131.70 ?  1050 GLN Q N   1 
ATOM 2347 C CA  . GLN A 1 424 ? 126.111 114.692 80.951  1.00 131.70 ?  1050 GLN Q CA  1 
ATOM 2348 C C   . GLN A 1 424 ? 124.975 113.764 81.353  1.00 131.70 ?  1050 GLN Q C   1 
ATOM 2349 O O   . GLN A 1 424 ? 125.046 113.106 82.395  1.00 131.70 ?  1050 GLN Q O   1 
ATOM 2350 C CB  . GLN A 1 424 ? 125.751 116.143 81.271  1.00 131.70 ?  1050 GLN Q CB  1 
ATOM 2351 C CG  . GLN A 1 424 ? 126.847 117.161 81.019  1.00 131.70 ?  1050 GLN Q CG  1 
ATOM 2352 C CD  . GLN A 1 424 ? 128.178 116.761 81.629  1.00 131.70 ?  1050 GLN Q CD  1 
ATOM 2353 O OE1 . GLN A 1 424 ? 129.230 117.098 81.104  1.00 131.70 ?  1050 GLN Q OE1 1 
ATOM 2354 N NE2 . GLN A 1 424 ? 128.136 116.076 82.767  1.00 131.70 ?  1050 GLN Q NE2 1 
ATOM 2355 N N   . LYS A 1 425 ? 123.919 113.698 80.542  1.00 137.70 ?  1051 LYS Q N   1 
ATOM 2356 C CA  . LYS A 1 425 ? 122.830 112.771 80.834  1.00 137.70 ?  1051 LYS Q CA  1 
ATOM 2357 C C   . LYS A 1 425 ? 123.307 111.327 80.741  1.00 137.70 ?  1051 LYS Q C   1 
ATOM 2358 O O   . LYS A 1 425 ? 122.867 110.462 81.509  1.00 137.70 ?  1051 LYS Q O   1 
ATOM 2359 C CB  . LYS A 1 425 ? 121.659 113.027 79.884  1.00 137.70 ?  1051 LYS Q CB  1 
ATOM 2360 C CG  . LYS A 1 425 ? 120.414 112.202 80.173  1.00 137.70 ?  1051 LYS Q CG  1 
ATOM 2361 C CD  . LYS A 1 425 ? 120.232 111.100 79.143  1.00 137.70 ?  1051 LYS Q CD  1 
ATOM 2362 C CE  . LYS A 1 425 ? 119.912 111.677 77.772  1.00 137.70 ?  1051 LYS Q CE  1 
ATOM 2363 N NZ  . LYS A 1 425 ? 119.744 110.615 76.742  1.00 137.70 1  1051 LYS Q NZ  1 
ATOM 2364 N N   . ASP A 1 426 ? 124.210 111.050 79.801  1.00 138.07 ?  1052 ASP Q N   1 
ATOM 2365 C CA  . ASP A 1 426 ? 124.782 109.713 79.697  1.00 138.07 ?  1052 ASP Q CA  1 
ATOM 2366 C C   . ASP A 1 426 ? 125.523 109.331 80.972  1.00 138.07 ?  1052 ASP Q C   1 
ATOM 2367 O O   . ASP A 1 426 ? 125.392 108.205 81.461  1.00 138.07 ?  1052 ASP Q O   1 
ATOM 2368 C CB  . ASP A 1 426 ? 125.713 109.638 78.488  1.00 138.07 ?  1052 ASP Q CB  1 
ATOM 2369 C CG  . ASP A 1 426 ? 124.962 109.424 77.188  1.00 138.07 ?  1052 ASP Q CG  1 
ATOM 2370 O OD1 . ASP A 1 426 ? 123.714 109.396 77.220  1.00 138.07 ?  1052 ASP Q OD1 1 
ATOM 2371 O OD2 . ASP A 1 426 ? 125.619 109.290 76.134  1.00 138.07 -1 1052 ASP Q OD2 1 
ATOM 2372 N N   . VAL A 1 427 ? 126.307 110.258 81.525  1.00 140.85 ?  1053 VAL Q N   1 
ATOM 2373 C CA  . VAL A 1 427 ? 127.012 110.000 82.779  1.00 140.85 ?  1053 VAL Q CA  1 
ATOM 2374 C C   . VAL A 1 427 ? 126.019 109.879 83.930  1.00 140.85 ?  1053 VAL Q C   1 
ATOM 2375 O O   . VAL A 1 427 ? 126.208 109.083 84.858  1.00 140.85 ?  1053 VAL Q O   1 
ATOM 2376 C CB  . VAL A 1 427 ? 128.059 111.103 83.028  1.00 140.85 ?  1053 VAL Q CB  1 
ATOM 2377 C CG1 . VAL A 1 427 ? 128.586 111.046 84.451  1.00 140.85 ?  1053 VAL Q CG1 1 
ATOM 2378 C CG2 . VAL A 1 427 ? 129.203 110.978 82.030  1.00 140.85 ?  1053 VAL Q CG2 1 
ATOM 2379 N N   . MET A 1 428 ? 124.945 110.668 83.881  1.00 143.15 ?  1054 MET Q N   1 
ATOM 2380 C CA  . MET A 1 428 ? 123.847 110.539 84.833  1.00 143.15 ?  1054 MET Q CA  1 
ATOM 2381 C C   . MET A 1 428 ? 123.347 109.100 84.890  1.00 143.15 ?  1054 MET Q C   1 
ATOM 2382 O O   . MET A 1 428 ? 123.306 108.481 85.966  1.00 143.15 ?  1054 MET Q O   1 
ATOM 2383 C CB  . MET A 1 428 ? 122.733 111.500 84.398  1.00 143.15 ?  1054 MET Q CB  1 
ATOM 2384 C CG  . MET A 1 428 ? 121.682 111.978 85.397  1.00 143.15 ?  1054 MET Q CG  1 
ATOM 2385 S SD  . MET A 1 428 ? 122.168 112.289 87.094  1.00 143.15 ?  1054 MET Q SD  1 
ATOM 2386 C CE  . MET A 1 428 ? 121.803 110.687 87.771  1.00 143.15 ?  1054 MET Q CE  1 
ATOM 2387 N N   . ARG A 1 429 ? 123.019 108.535 83.725  1.00 147.46 ?  1055 ARG Q N   1 
ATOM 2388 C CA  . ARG A 1 429 ? 122.578 107.144 83.666  1.00 147.46 ?  1055 ARG Q CA  1 
ATOM 2389 C C   . ARG A 1 429 ? 123.679 106.189 84.109  1.00 147.46 ?  1055 ARG Q C   1 
ATOM 2390 O O   . ARG A 1 429 ? 123.427 105.254 84.877  1.00 147.46 ?  1055 ARG Q O   1 
ATOM 2391 C CB  . ARG A 1 429 ? 122.111 106.789 82.254  1.00 147.46 ?  1055 ARG Q CB  1 
ATOM 2392 C CG  . ARG A 1 429 ? 121.308 107.868 81.566  1.00 147.46 ?  1055 ARG Q CG  1 
ATOM 2393 C CD  . ARG A 1 429 ? 121.629 107.929 80.081  1.00 147.46 ?  1055 ARG Q CD  1 
ATOM 2394 N NE  . ARG A 1 429 ? 120.853 106.975 79.300  1.00 147.46 ?  1055 ARG Q NE  1 
ATOM 2395 C CZ  . ARG A 1 429 ? 121.111 106.654 78.040  1.00 147.46 ?  1055 ARG Q CZ  1 
ATOM 2396 N NH1 . ARG A 1 429 ? 122.126 107.193 77.383  1.00 147.46 1  1055 ARG Q NH1 1 
ATOM 2397 N NH2 . ARG A 1 429 ? 120.333 105.770 77.423  1.00 147.46 ?  1055 ARG Q NH2 1 
ATOM 2398 N N   . GLY A 1 430 ? 124.907 106.408 83.639  1.00 151.54 ?  1056 GLY Q N   1 
ATOM 2399 C CA  . GLY A 1 430 ? 125.983 105.482 83.952  1.00 151.54 ?  1056 GLY Q CA  1 
ATOM 2400 C C   . GLY A 1 430 ? 126.259 105.387 85.439  1.00 151.54 ?  1056 GLY Q C   1 
ATOM 2401 O O   . GLY A 1 430 ? 126.588 104.316 85.952  1.00 151.54 ?  1056 GLY Q O   1 
ATOM 2402 N N   . ILE A 1 431 ? 126.125 106.504 86.152  1.00 154.85 ?  1057 ILE Q N   1 
ATOM 2403 C CA  . ILE A 1 431 ? 126.369 106.487 87.588  1.00 154.85 ?  1057 ILE Q CA  1 
ATOM 2404 C C   . ILE A 1 431 ? 125.163 105.920 88.327  1.00 154.85 ?  1057 ILE Q C   1 
ATOM 2405 O O   . ILE A 1 431 ? 125.284 104.950 89.084  1.00 154.85 ?  1057 ILE Q O   1 
ATOM 2406 C CB  . ILE A 1 431 ? 126.740 107.892 88.096  1.00 154.85 ?  1057 ILE Q CB  1 
ATOM 2407 C CG1 . ILE A 1 431 ? 128.118 108.302 87.569  1.00 154.85 ?  1057 ILE Q CG1 1 
ATOM 2408 C CG2 . ILE A 1 431 ? 126.725 107.930 89.613  1.00 154.85 ?  1057 ILE Q CG2 1 
ATOM 2409 C CD1 . ILE A 1 431 ? 128.470 109.751 87.827  1.00 154.85 ?  1057 ILE Q CD1 1 
ATOM 2410 N N   . TYR A 1 432 ? 123.980 106.497 88.111  1.00 153.71 ?  1058 TYR Q N   1 
ATOM 2411 C CA  . TYR A 1 432 ? 122.805 106.104 88.886  1.00 153.71 ?  1058 TYR Q CA  1 
ATOM 2412 C C   . TYR A 1 432 ? 122.013 104.970 88.241  1.00 153.71 ?  1058 TYR Q C   1 
ATOM 2413 O O   . TYR A 1 432 ? 121.763 103.949 88.887  1.00 153.71 ?  1058 TYR Q O   1 
ATOM 2414 C CB  . TYR A 1 432 ? 121.927 107.333 89.142  1.00 153.71 ?  1058 TYR Q CB  1 
ATOM 2415 C CG  . TYR A 1 432 ? 122.460 108.207 90.258  1.00 153.71 ?  1058 TYR Q CG  1 
ATOM 2416 C CD1 . TYR A 1 432 ? 123.491 109.106 90.034  1.00 153.71 ?  1058 TYR Q CD1 1 
ATOM 2417 C CD2 . TYR A 1 432 ? 121.996 108.060 91.557  1.00 153.71 ?  1058 TYR Q CD2 1 
ATOM 2418 C CE1 . TYR A 1 432 ? 123.995 109.888 91.054  1.00 153.71 ?  1058 TYR Q CE1 1 
ATOM 2419 C CE2 . TYR A 1 432 ? 122.490 108.841 92.586  1.00 153.71 ?  1058 TYR Q CE2 1 
ATOM 2420 C CZ  . TYR A 1 432 ? 123.495 109.750 92.329  1.00 153.71 ?  1058 TYR Q CZ  1 
ATOM 2421 O OH  . TYR A 1 432 ? 123.999 110.526 93.346  1.00 153.71 ?  1058 TYR Q OH  1 
ATOM 2422 N N   . GLU A 1 433 ? 121.606 105.125 86.979  1.00 159.72 ?  1059 GLU Q N   1 
ATOM 2423 C CA  . GLU A 1 433 ? 120.950 104.016 86.292  1.00 159.72 ?  1059 GLU Q CA  1 
ATOM 2424 C C   . GLU A 1 433 ? 121.917 102.868 86.023  1.00 159.72 ?  1059 GLU Q C   1 
ATOM 2425 O O   . GLU A 1 433 ? 121.478 101.756 85.712  1.00 159.72 ?  1059 GLU Q O   1 
ATOM 2426 C CB  . GLU A 1 433 ? 120.322 104.502 84.982  1.00 159.72 ?  1059 GLU Q CB  1 
ATOM 2427 C CG  . GLU A 1 433 ? 119.393 103.495 84.313  1.00 159.72 ?  1059 GLU Q CG  1 
ATOM 2428 C CD  . GLU A 1 433 ? 119.082 103.846 82.872  1.00 159.72 ?  1059 GLU Q CD  1 
ATOM 2429 O OE1 . GLU A 1 433 ? 119.471 104.947 82.428  1.00 159.72 ?  1059 GLU Q OE1 1 
ATOM 2430 O OE2 . GLU A 1 433 ? 118.449 103.019 82.183  1.00 159.72 -1 1059 GLU Q OE2 1 
ATOM 2431 N N   . GLY A 1 434 ? 123.218 103.110 86.162  1.00 161.01 ?  1060 GLY Q N   1 
ATOM 2432 C CA  . GLY A 1 434 ? 124.236 102.116 85.886  1.00 161.01 ?  1060 GLY Q CA  1 
ATOM 2433 C C   . GLY A 1 434 ? 124.792 101.456 87.131  1.00 161.01 ?  1060 GLY Q C   1 
ATOM 2434 O O   . GLY A 1 434 ? 124.209 100.496 87.645  1.00 161.01 ?  1060 GLY Q O   1 
ATOM 2435 N N   . VAL A 1 435 ? 125.935 101.955 87.609  1.00 160.61 ?  1061 VAL Q N   1 
ATOM 2436 C CA  . VAL A 1 435 ? 126.630 101.324 88.730  1.00 160.61 ?  1061 VAL Q CA  1 
ATOM 2437 C C   . VAL A 1 435 ? 125.731 101.264 89.960  1.00 160.61 ?  1061 VAL Q C   1 
ATOM 2438 O O   . VAL A 1 435 ? 125.658 100.237 90.646  1.00 160.61 ?  1061 VAL Q O   1 
ATOM 2439 C CB  . VAL A 1 435 ? 127.943 102.069 89.031  1.00 160.61 ?  1061 VAL Q CB  1 
ATOM 2440 C CG1 . VAL A 1 435 ? 128.738 101.336 90.101  1.00 160.61 ?  1061 VAL Q CG1 1 
ATOM 2441 C CG2 . VAL A 1 435 ? 128.765 102.225 87.762  1.00 160.61 ?  1061 VAL Q CG2 1 
ATOM 2442 N N   . LYS A 1 436 ? 125.036 102.363 90.262  1.00 158.26 ?  1062 LYS Q N   1 
ATOM 2443 C CA  . LYS A 1 436 ? 124.217 102.395 91.470  1.00 158.26 ?  1062 LYS Q CA  1 
ATOM 2444 C C   . LYS A 1 436 ? 123.005 101.478 91.354  1.00 158.26 ?  1062 LYS Q C   1 
ATOM 2445 O O   . LYS A 1 436 ? 122.594 100.859 92.343  1.00 158.26 ?  1062 LYS Q O   1 
ATOM 2446 C CB  . LYS A 1 436 ? 123.777 103.825 91.775  1.00 158.26 ?  1062 LYS Q CB  1 
ATOM 2447 C CG  . LYS A 1 436 ? 123.325 104.015 93.215  1.00 158.26 ?  1062 LYS Q CG  1 
ATOM 2448 C CD  . LYS A 1 436 ? 123.003 105.465 93.513  1.00 158.26 ?  1062 LYS Q CD  1 
ATOM 2449 C CE  . LYS A 1 436 ? 122.828 105.701 95.004  1.00 158.26 ?  1062 LYS Q CE  1 
ATOM 2450 N NZ  . LYS A 1 436 ? 124.089 105.453 95.755  1.00 158.26 1  1062 LYS Q NZ  1 
ATOM 2451 N N   . ALA A 1 437 ? 122.417 101.376 90.162  1.00 162.25 ?  1063 ALA Q N   1 
ATOM 2452 C CA  . ALA A 1 437 ? 121.213 100.574 89.979  1.00 162.25 ?  1063 ALA Q CA  1 
ATOM 2453 C C   . ALA A 1 437 ? 121.494 99.081  89.870  1.00 162.25 ?  1063 ALA Q C   1 
ATOM 2454 O O   . ALA A 1 437 ? 120.543 98.294  89.802  1.00 162.25 ?  1063 ALA Q O   1 
ATOM 2455 C CB  . ALA A 1 437 ? 120.451 101.038 88.736  1.00 162.25 ?  1063 ALA Q CB  1 
ATOM 2456 N N   . GLY A 1 438 ? 122.760 98.673  89.850  1.00 162.33 ?  1064 GLY Q N   1 
ATOM 2457 C CA  . GLY A 1 438 ? 123.124 97.281  89.704  1.00 162.33 ?  1064 GLY Q CA  1 
ATOM 2458 C C   . GLY A 1 438 ? 123.484 96.868  88.294  1.00 162.33 ?  1064 GLY Q C   1 
ATOM 2459 O O   . GLY A 1 438 ? 124.073 95.795  88.113  1.00 162.33 ?  1064 GLY Q O   1 
ATOM 2460 N N   . ASN A 1 439 ? 123.149 97.683  87.293  1.00 161.24 ?  1065 ASN Q N   1 
ATOM 2461 C CA  . ASN A 1 439 ? 123.536 97.421  85.908  1.00 161.24 ?  1065 ASN Q CA  1 
ATOM 2462 C C   . ASN A 1 439 ? 124.951 97.958  85.709  1.00 161.24 ?  1065 ASN Q C   1 
ATOM 2463 O O   . ASN A 1 439 ? 125.179 99.028  85.138  1.00 161.24 ?  1065 ASN Q O   1 
ATOM 2464 C CB  . ASN A 1 439 ? 122.544 98.054  84.941  1.00 161.24 ?  1065 ASN Q CB  1 
ATOM 2465 C CG  . ASN A 1 439 ? 122.656 97.490  83.537  1.00 161.24 ?  1065 ASN Q CG  1 
ATOM 2466 O OD1 . ASN A 1 439 ? 123.643 96.839  83.192  1.00 161.24 ?  1065 ASN Q OD1 1 
ATOM 2467 N ND2 . ASN A 1 439 ? 121.640 97.737  82.719  1.00 161.24 ?  1065 ASN Q ND2 1 
ATOM 2468 N N   . LEU A 1 440 ? 125.921 97.188  86.207  1.00 154.18 ?  1066 LEU Q N   1 
ATOM 2469 C CA  . LEU A 1 440 ? 127.315 97.615  86.150  1.00 154.18 ?  1066 LEU Q CA  1 
ATOM 2470 C C   . LEU A 1 440 ? 127.811 97.746  84.717  1.00 154.18 ?  1066 LEU Q C   1 
ATOM 2471 O O   . LEU A 1 440 ? 128.616 98.636  84.421  1.00 154.18 ?  1066 LEU Q O   1 
ATOM 2472 C CB  . LEU A 1 440 ? 128.192 96.631  86.923  1.00 154.18 ?  1066 LEU Q CB  1 
ATOM 2473 C CG  . LEU A 1 440 ? 127.977 96.550  88.435  1.00 154.18 ?  1066 LEU Q CG  1 
ATOM 2474 C CD1 . LEU A 1 440 ? 128.724 95.359  89.018  1.00 154.18 ?  1066 LEU Q CD1 1 
ATOM 2475 C CD2 . LEU A 1 440 ? 128.415 97.839  89.105  1.00 154.18 ?  1066 LEU Q CD2 1 
ATOM 2476 N N   . LYS A 1 441 ? 127.350 96.870  83.822  1.00 151.80 ?  1067 LYS Q N   1 
ATOM 2477 C CA  . LYS A 1 441 ? 127.831 96.882  82.443  1.00 151.80 ?  1067 LYS Q CA  1 
ATOM 2478 C C   . LYS A 1 441 ? 127.493 98.197  81.749  1.00 151.80 ?  1067 LYS Q C   1 
ATOM 2479 O O   . LYS A 1 441 ? 128.344 98.800  81.084  1.00 151.80 ?  1067 LYS Q O   1 
ATOM 2480 C CB  . LYS A 1 441 ? 127.240 95.699  81.676  1.00 151.80 ?  1067 LYS Q CB  1 
ATOM 2481 C CG  . LYS A 1 441 ? 127.592 95.677  80.197  1.00 151.80 ?  1067 LYS Q CG  1 
ATOM 2482 C CD  . LYS A 1 441 ? 126.794 94.614  79.459  1.00 151.80 ?  1067 LYS Q CD  1 
ATOM 2483 C CE  . LYS A 1 441 ? 127.037 94.681  77.961  1.00 151.80 ?  1067 LYS Q CE  1 
ATOM 2484 N NZ  . LYS A 1 441 ? 126.175 93.722  77.216  1.00 151.80 1  1067 LYS Q NZ  1 
ATOM 2485 N N   . LEU A 1 442 ? 126.249 98.657  81.893  1.00 154.73 ?  1068 LEU Q N   1 
ATOM 2486 C CA  . LEU A 1 442 ? 125.860 99.921  81.276  1.00 154.73 ?  1068 LEU Q CA  1 
ATOM 2487 C C   . LEU A 1 442 ? 126.665 101.078 81.849  1.00 154.73 ?  1068 LEU Q C   1 
ATOM 2488 O O   . LEU A 1 442 ? 127.109 101.966 81.108  1.00 154.73 ?  1068 LEU Q O   1 
ATOM 2489 C CB  . LEU A 1 442 ? 124.362 100.160 81.469  1.00 154.73 ?  1068 LEU Q CB  1 
ATOM 2490 C CG  . LEU A 1 442 ? 123.815 101.499 80.970  1.00 154.73 ?  1068 LEU Q CG  1 
ATOM 2491 C CD1 . LEU A 1 442 ? 123.902 101.585 79.454  1.00 154.73 ?  1068 LEU Q CD1 1 
ATOM 2492 C CD2 . LEU A 1 442 ? 122.383 101.704 81.442  1.00 154.73 ?  1068 LEU Q CD2 1 
ATOM 2493 N N   . GLY A 1 443 ? 126.867 101.081 83.167  1.00 149.28 ?  1069 GLY Q N   1 
ATOM 2494 C CA  . GLY A 1 443 ? 127.637 102.148 83.782  1.00 149.28 ?  1069 GLY Q CA  1 
ATOM 2495 C C   . GLY A 1 443 ? 129.063 102.200 83.272  1.00 149.28 ?  1069 GLY Q C   1 
ATOM 2496 O O   . GLY A 1 443 ? 129.563 103.264 82.898  1.00 149.28 ?  1069 GLY Q O   1 
ATOM 2497 N N   . ARG A 1 444 ? 129.736 101.046 83.239  1.00 149.30 ?  1070 ARG Q N   1 
ATOM 2498 C CA  . ARG A 1 444 ? 131.116 101.037 82.767  1.00 149.30 ?  1070 ARG Q CA  1 
ATOM 2499 C C   . ARG A 1 444 ? 131.187 101.413 81.295  1.00 149.30 ?  1070 ARG Q C   1 
ATOM 2500 O O   . ARG A 1 444 ? 132.093 102.142 80.883  1.00 149.30 ?  1070 ARG Q O   1 
ATOM 2501 C CB  . ARG A 1 444 ? 131.779 99.679  83.008  1.00 149.30 ?  1070 ARG Q CB  1 
ATOM 2502 C CG  . ARG A 1 444 ? 131.019 98.480  82.492  1.00 149.30 ?  1070 ARG Q CG  1 
ATOM 2503 C CD  . ARG A 1 444 ? 131.497 97.199  83.150  1.00 149.30 ?  1070 ARG Q CD  1 
ATOM 2504 N NE  . ARG A 1 444 ? 131.348 97.238  84.600  1.00 149.30 ?  1070 ARG Q NE  1 
ATOM 2505 C CZ  . ARG A 1 444 ? 131.516 96.193  85.397  1.00 149.30 ?  1070 ARG Q CZ  1 
ATOM 2506 N NH1 . ARG A 1 444 ? 131.811 94.997  84.915  1.00 149.30 1  1070 ARG Q NH1 1 
ATOM 2507 N NH2 . ARG A 1 444 ? 131.390 96.352  86.711  1.00 149.30 ?  1070 ARG Q NH2 1 
ATOM 2508 N N   . GLU A 1 445 ? 130.229 100.947 80.489  1.00 146.35 ?  1071 GLU Q N   1 
ATOM 2509 C CA  . GLU A 1 445 ? 130.229 101.297 79.074  1.00 146.35 ?  1071 GLU Q CA  1 
ATOM 2510 C C   . GLU A 1 445 ? 130.103 102.804 78.883  1.00 146.35 ?  1071 GLU Q C   1 
ATOM 2511 O O   . GLU A 1 445 ? 130.895 103.419 78.156  1.00 146.35 ?  1071 GLU Q O   1 
ATOM 2512 C CB  . GLU A 1 445 ? 129.097 100.560 78.356  1.00 146.35 ?  1071 GLU Q CB  1 
ATOM 2513 C CG  . GLU A 1 445 ? 128.509 101.309 77.169  1.00 146.35 ?  1071 GLU Q CG  1 
ATOM 2514 C CD  . GLU A 1 445 ? 127.060 100.944 76.911  1.00 146.35 ?  1071 GLU Q CD  1 
ATOM 2515 O OE1 . GLU A 1 445 ? 126.505 100.130 77.678  1.00 146.35 ?  1071 GLU Q OE1 1 
ATOM 2516 O OE2 . GLU A 1 445 ? 126.476 101.473 75.942  1.00 146.35 -1 1071 GLU Q OE2 1 
ATOM 2517 N N   . LEU A 1 446 ? 129.116 103.418 79.542  1.00 145.26 ?  1072 LEU Q N   1 
ATOM 2518 C CA  . LEU A 1 446 ? 128.897 104.851 79.375  1.00 145.26 ?  1072 LEU Q CA  1 
ATOM 2519 C C   . LEU A 1 446 ? 130.084 105.653 79.890  1.00 145.26 ?  1072 LEU Q C   1 
ATOM 2520 O O   . LEU A 1 446 ? 130.545 106.595 79.230  1.00 145.26 ?  1072 LEU Q O   1 
ATOM 2521 C CB  . LEU A 1 446 ? 127.611 105.270 80.087  1.00 145.26 ?  1072 LEU Q CB  1 
ATOM 2522 C CG  . LEU A 1 446 ? 126.316 104.703 79.502  1.00 145.26 ?  1072 LEU Q CG  1 
ATOM 2523 C CD1 . LEU A 1 446 ? 125.107 105.189 80.285  1.00 145.26 ?  1072 LEU Q CD1 1 
ATOM 2524 C CD2 . LEU A 1 446 ? 126.188 105.067 78.030  1.00 145.26 ?  1072 LEU Q CD2 1 
ATOM 2525 N N   . LEU A 1 447 ? 130.602 105.288 81.063  1.00 141.73 ?  1073 LEU Q N   1 
ATOM 2526 C CA  . LEU A 1 447 ? 131.743 106.009 81.605  1.00 141.73 ?  1073 LEU Q CA  1 
ATOM 2527 C C   . LEU A 1 447 ? 132.959 105.866 80.703  1.00 141.73 ?  1073 LEU Q C   1 
ATOM 2528 O O   . LEU A 1 447 ? 133.706 106.830 80.505  1.00 141.73 ?  1073 LEU Q O   1 
ATOM 2529 C CB  . LEU A 1 447 ? 132.048 105.522 83.021  1.00 141.73 ?  1073 LEU Q CB  1 
ATOM 2530 C CG  . LEU A 1 447 ? 131.005 105.925 84.066  1.00 141.73 ?  1073 LEU Q CG  1 
ATOM 2531 C CD1 . LEU A 1 447 ? 131.378 105.396 85.439  1.00 141.73 ?  1073 LEU Q CD1 1 
ATOM 2532 C CD2 . LEU A 1 447 ? 130.833 107.436 84.099  1.00 141.73 ?  1073 LEU Q CD2 1 
ATOM 2533 N N   . LEU A 1 448 ? 133.169 104.677 80.131  1.00 136.29 ?  1074 LEU Q N   1 
ATOM 2534 C CA  . LEU A 1 448 ? 134.339 104.481 79.287  1.00 136.29 ?  1074 LEU Q CA  1 
ATOM 2535 C C   . LEU A 1 448 ? 134.226 105.276 77.995  1.00 136.29 ?  1074 LEU Q C   1 
ATOM 2536 O O   . LEU A 1 448 ? 135.213 105.868 77.549  1.00 136.29 ?  1074 LEU Q O   1 
ATOM 2537 C CB  . LEU A 1 448 ? 134.560 102.990 79.010  1.00 136.29 ?  1074 LEU Q CB  1 
ATOM 2538 C CG  . LEU A 1 448 ? 133.788 102.197 77.953  1.00 136.29 ?  1074 LEU Q CG  1 
ATOM 2539 C CD1 . LEU A 1 448 ? 134.454 102.286 76.588  1.00 136.29 ?  1074 LEU Q CD1 1 
ATOM 2540 C CD2 . LEU A 1 448 ? 133.685 100.745 78.384  1.00 136.29 ?  1074 LEU Q CD2 1 
ATOM 2541 N N   . LYS A 1 449 ? 133.040 105.319 77.379  1.00 135.41 ?  1075 LYS Q N   1 
ATOM 2542 C CA  . LYS A 1 449 ? 132.933 106.117 76.159  1.00 135.41 ?  1075 LYS Q CA  1 
ATOM 2543 C C   . LYS A 1 449 ? 133.099 107.600 76.464  1.00 135.41 ?  1075 LYS Q C   1 
ATOM 2544 O O   . LYS A 1 449 ? 133.740 108.328 75.695  1.00 135.41 ?  1075 LYS Q O   1 
ATOM 2545 C CB  . LYS A 1 449 ? 131.611 105.870 75.429  1.00 135.41 ?  1075 LYS Q CB  1 
ATOM 2546 C CG  . LYS A 1 449 ? 130.395 105.711 76.299  1.00 135.41 ?  1075 LYS Q CG  1 
ATOM 2547 C CD  . LYS A 1 449 ? 129.124 105.594 75.471  1.00 135.41 ?  1075 LYS Q CD  1 
ATOM 2548 C CE  . LYS A 1 449 ? 129.350 104.783 74.205  1.00 135.41 ?  1075 LYS Q CE  1 
ATOM 2549 N NZ  . LYS A 1 449 ? 129.528 103.333 74.496  1.00 135.41 1  1075 LYS Q NZ  1 
ATOM 2550 N N   . THR A 1 450 ? 132.537 108.065 77.585  1.00 135.32 ?  1076 THR Q N   1 
ATOM 2551 C CA  . THR A 1 450 ? 132.699 109.467 77.958  1.00 135.32 ?  1076 THR Q CA  1 
ATOM 2552 C C   . THR A 1 450 ? 134.167 109.801 78.198  1.00 135.32 ?  1076 THR Q C   1 
ATOM 2553 O O   . THR A 1 450 ? 134.672 110.828 77.727  1.00 135.32 ?  1076 THR Q O   1 
ATOM 2554 C CB  . THR A 1 450 ? 131.867 109.778 79.203  1.00 135.32 ?  1076 THR Q CB  1 
ATOM 2555 O OG1 . THR A 1 450 ? 130.480 109.552 78.922  1.00 135.32 ?  1076 THR Q OG1 1 
ATOM 2556 C CG2 . THR A 1 450 ? 132.063 111.227 79.628  1.00 135.32 ?  1076 THR Q CG2 1 
ATOM 2557 N N   . ALA A 1 451 ? 134.871 108.935 78.926  1.00 137.11 ?  1077 ALA Q N   1 
ATOM 2558 C CA  . ALA A 1 451 ? 136.288 109.161 79.173  1.00 137.11 ?  1077 ALA Q CA  1 
ATOM 2559 C C   . ALA A 1 451 ? 137.077 109.129 77.874  1.00 137.11 ?  1077 ALA Q C   1 
ATOM 2560 O O   . ALA A 1 451 ? 138.019 109.905 77.695  1.00 137.11 ?  1077 ALA Q O   1 
ATOM 2561 C CB  . ALA A 1 451 ? 136.822 108.123 80.158  1.00 137.11 ?  1077 ALA Q CB  1 
ATOM 2562 N N   . LYS A 1 452 ? 136.704 108.240 76.955  1.00 135.12 ?  1078 LYS Q N   1 
ATOM 2563 C CA  . LYS A 1 452 ? 137.406 108.142 75.682  1.00 135.12 ?  1078 LYS Q CA  1 
ATOM 2564 C C   . LYS A 1 452 ? 137.253 109.429 74.879  1.00 135.12 ?  1078 LYS Q C   1 
ATOM 2565 O O   . LYS A 1 452 ? 138.239 109.968 74.360  1.00 135.12 ?  1078 LYS Q O   1 
ATOM 2566 C CB  . LYS A 1 452 ? 136.885 106.917 74.918  1.00 135.12 ?  1078 LYS Q CB  1 
ATOM 2567 C CG  . LYS A 1 452 ? 136.637 107.041 73.409  1.00 135.12 ?  1078 LYS Q CG  1 
ATOM 2568 C CD  . LYS A 1 452 ? 137.891 107.346 72.597  1.00 135.12 ?  1078 LYS Q CD  1 
ATOM 2569 C CE  . LYS A 1 452 ? 137.517 108.003 71.282  1.00 135.12 ?  1078 LYS Q CE  1 
ATOM 2570 N NZ  . LYS A 1 452 ? 137.310 109.465 71.448  1.00 135.12 1  1078 LYS Q NZ  1 
ATOM 2571 N N   . ILE A 1 453 ? 136.028 109.952 74.780  1.00 131.78 ?  1079 ILE Q N   1 
ATOM 2572 C CA  . ILE A 1 453 ? 135.840 111.163 73.986  1.00 131.78 ?  1079 ILE Q CA  1 
ATOM 2573 C C   . ILE A 1 453 ? 136.520 112.345 74.669  1.00 131.78 ?  1079 ILE Q C   1 
ATOM 2574 O O   . ILE A 1 453 ? 137.127 113.195 74.005  1.00 131.78 ?  1079 ILE Q O   1 
ATOM 2575 C CB  . ILE A 1 453 ? 134.346 111.434 73.719  1.00 131.78 ?  1079 ILE Q CB  1 
ATOM 2576 C CG1 . ILE A 1 453 ? 134.126 112.851 73.181  1.00 131.78 ?  1079 ILE Q CG1 1 
ATOM 2577 C CG2 . ILE A 1 453 ? 133.529 111.278 74.967  1.00 131.78 ?  1079 ILE Q CG2 1 
ATOM 2578 C CD1 . ILE A 1 453 ? 134.842 113.139 71.872  1.00 131.78 ?  1079 ILE Q CD1 1 
ATOM 2579 N N   . LEU A 1 454 ? 136.460 112.408 76.003  1.00 139.92 ?  1080 LEU Q N   1 
ATOM 2580 C CA  . LEU A 1 454 ? 137.145 113.487 76.708  1.00 139.92 ?  1080 LEU Q CA  1 
ATOM 2581 C C   . LEU A 1 454 ? 138.652 113.416 76.494  1.00 139.92 ?  1080 LEU Q C   1 
ATOM 2582 O O   . LEU A 1 454 ? 139.305 114.443 76.277  1.00 139.92 ?  1080 LEU Q O   1 
ATOM 2583 C CB  . LEU A 1 454 ? 136.811 113.441 78.199  1.00 139.92 ?  1080 LEU Q CB  1 
ATOM 2584 C CG  . LEU A 1 454 ? 135.483 114.076 78.618  1.00 139.92 ?  1080 LEU Q CG  1 
ATOM 2585 C CD1 . LEU A 1 454 ? 135.429 114.263 80.126  1.00 139.92 ?  1080 LEU Q CD1 1 
ATOM 2586 C CD2 . LEU A 1 454 ? 135.268 115.401 77.903  1.00 139.92 ?  1080 LEU Q CD2 1 
ATOM 2587 N N   . GLU A 1 455 ? 139.220 112.210 76.549  1.00 145.57 ?  1081 GLU Q N   1 
ATOM 2588 C CA  . GLU A 1 455 ? 140.651 112.045 76.325  1.00 145.57 ?  1081 GLU Q CA  1 
ATOM 2589 C C   . GLU A 1 455 ? 141.033 112.448 74.910  1.00 145.57 ?  1081 GLU Q C   1 
ATOM 2590 O O   . GLU A 1 455 ? 142.077 113.074 74.694  1.00 145.57 ?  1081 GLU Q O   1 
ATOM 2591 C CB  . GLU A 1 455 ? 141.058 110.597 76.600  1.00 145.57 ?  1081 GLU Q CB  1 
ATOM 2592 C CG  . GLU A 1 455 ? 142.553 110.386 76.769  1.00 145.57 ?  1081 GLU Q CG  1 
ATOM 2593 C CD  . GLU A 1 455 ? 142.906 108.938 77.051  1.00 145.57 ?  1081 GLU Q CD  1 
ATOM 2594 O OE1 . GLU A 1 455 ? 142.308 108.045 76.414  1.00 145.57 ?  1081 GLU Q OE1 1 
ATOM 2595 O OE2 . GLU A 1 455 ? 143.783 108.691 77.905  1.00 145.57 -1 1081 GLU Q OE2 1 
ATOM 2596 N N   . GLU A 1 456 ? 140.198 112.093 73.931  1.00 145.07 ?  1082 GLU Q N   1 
ATOM 2597 C CA  . GLU A 1 456 ? 140.485 112.472 72.553  1.00 145.07 ?  1082 GLU Q CA  1 
ATOM 2598 C C   . GLU A 1 456 ? 140.461 113.984 72.371  1.00 145.07 ?  1082 GLU Q C   1 
ATOM 2599 O O   . GLU A 1 456 ? 141.124 114.509 71.469  1.00 145.07 ?  1082 GLU Q O   1 
ATOM 2600 C CB  . GLU A 1 456 ? 139.487 111.806 71.608  1.00 145.07 ?  1082 GLU Q CB  1 
ATOM 2601 C CG  . GLU A 1 456 ? 139.807 111.985 70.132  1.00 145.07 ?  1082 GLU Q CG  1 
ATOM 2602 C CD  . GLU A 1 456 ? 138.938 111.126 69.237  1.00 145.07 ?  1082 GLU Q CD  1 
ATOM 2603 O OE1 . GLU A 1 456 ? 139.212 109.912 69.129  1.00 145.07 ?  1082 GLU Q OE1 1 
ATOM 2604 O OE2 . GLU A 1 456 ? 137.981 111.663 68.642  1.00 145.07 -1 1082 GLU Q OE2 1 
ATOM 2605 N N   . ARG A 1 457 ? 139.721 114.699 73.217  1.00 141.47 ?  1083 ARG Q N   1 
ATOM 2606 C CA  . ARG A 1 457 ? 139.611 116.145 73.079  1.00 141.47 ?  1083 ARG Q CA  1 
ATOM 2607 C C   . ARG A 1 457 ? 140.804 116.898 73.656  1.00 141.47 ?  1083 ARG Q C   1 
ATOM 2608 O O   . ARG A 1 457 ? 140.899 118.113 73.454  1.00 141.47 ?  1083 ARG Q O   1 
ATOM 2609 C CB  . ARG A 1 457 ? 138.315 116.631 73.731  1.00 141.47 ?  1083 ARG Q CB  1 
ATOM 2610 C CG  . ARG A 1 457 ? 137.077 116.331 72.899  1.00 141.47 ?  1083 ARG Q CG  1 
ATOM 2611 C CD  . ARG A 1 457 ? 135.804 116.758 73.602  1.00 141.47 ?  1083 ARG Q CD  1 
ATOM 2612 N NE  . ARG A 1 457 ? 134.617 116.281 72.903  1.00 141.47 ?  1083 ARG Q NE  1 
ATOM 2613 C CZ  . ARG A 1 457 ? 133.396 116.275 73.418  1.00 141.47 ?  1083 ARG Q CZ  1 
ATOM 2614 N NH1 . ARG A 1 457 ? 133.159 116.719 74.641  1.00 141.47 1  1083 ARG Q NH1 1 
ATOM 2615 N NH2 . ARG A 1 457 ? 132.386 115.810 72.687  1.00 141.47 ?  1083 ARG Q NH2 1 
ATOM 2616 N N   . GLY A 1 458 ? 141.710 116.221 74.361  1.00 144.35 ?  1084 GLY Q N   1 
ATOM 2617 C CA  . GLY A 1 458 ? 142.955 116.847 74.763  1.00 144.35 ?  1084 GLY Q CA  1 
ATOM 2618 C C   . GLY A 1 458 ? 143.241 116.874 76.251  1.00 144.35 ?  1084 GLY Q C   1 
ATOM 2619 O O   . GLY A 1 458 ? 144.088 117.650 76.704  1.00 144.35 ?  1084 GLY Q O   1 
ATOM 2620 N N   . ALA A 1 459 ? 142.556 116.037 77.025  1.00 141.82 ?  1085 ALA Q N   1 
ATOM 2621 C CA  . ALA A 1 459 ? 142.759 116.006 78.467  1.00 141.82 ?  1085 ALA Q CA  1 
ATOM 2622 C C   . ALA A 1 459 ? 143.927 115.093 78.818  1.00 141.82 ?  1085 ALA Q C   1 
ATOM 2623 O O   . ALA A 1 459 ? 143.983 113.943 78.373  1.00 141.82 ?  1085 ALA Q O   1 
ATOM 2624 C CB  . ALA A 1 459 ? 141.489 115.538 79.174  1.00 141.82 ?  1085 ALA Q CB  1 
ATOM 2625 N N   . GLU A 1 460 ? 144.859 115.607 79.618  1.00 136.20 ?  1086 GLU Q N   1 
ATOM 2626 C CA  . GLU A 1 460 ? 146.001 114.828 80.078  1.00 136.20 ?  1086 GLU Q CA  1 
ATOM 2627 C C   . GLU A 1 460 ? 145.734 114.114 81.395  1.00 136.20 ?  1086 GLU Q C   1 
ATOM 2628 O O   . GLU A 1 460 ? 146.602 113.373 81.869  1.00 136.20 ?  1086 GLU Q O   1 
ATOM 2629 C CB  . GLU A 1 460 ? 147.233 115.727 80.225  1.00 136.20 ?  1086 GLU Q CB  1 
ATOM 2630 C CG  . GLU A 1 460 ? 146.978 117.002 81.005  1.00 136.20 ?  1086 GLU Q CG  1 
ATOM 2631 C CD  . GLU A 1 460 ? 146.605 118.174 80.120  1.00 136.20 ?  1086 GLU Q CD  1 
ATOM 2632 O OE1 . GLU A 1 460 ? 145.897 117.961 79.115  1.00 136.20 ?  1086 GLU Q OE1 1 
ATOM 2633 O OE2 . GLU A 1 460 ? 147.013 119.310 80.439  1.00 136.20 -1 1086 GLU Q OE2 1 
ATOM 2634 N N   . CYS A 1 461 ? 144.565 114.325 81.996  1.00 145.60 ?  1087 CYS Q N   1 
ATOM 2635 C CA  . CYS A 1 461 ? 144.194 113.651 83.231  1.00 145.60 ?  1087 CYS Q CA  1 
ATOM 2636 C C   . CYS A 1 461 ? 142.686 113.752 83.410  1.00 145.60 ?  1087 CYS Q C   1 
ATOM 2637 O O   . CYS A 1 461 ? 142.060 114.725 82.981  1.00 145.60 ?  1087 CYS Q O   1 
ATOM 2638 C CB  . CYS A 1 461 ? 144.925 114.243 84.442  1.00 145.60 ?  1087 CYS Q CB  1 
ATOM 2639 S SG  . CYS A 1 461 ? 144.370 115.888 84.933  1.00 145.60 ?  1087 CYS Q SG  1 
ATOM 2640 N N   . ILE A 1 462 ? 142.117 112.731 84.047  1.00 147.02 ?  1088 ILE Q N   1 
ATOM 2641 C CA  . ILE A 1 462 ? 140.678 112.599 84.236  1.00 147.02 ?  1088 ILE Q CA  1 
ATOM 2642 C C   . ILE A 1 462 ? 140.398 112.486 85.728  1.00 147.02 ?  1088 ILE Q C   1 
ATOM 2643 O O   . ILE A 1 462 ? 141.092 111.749 86.439  1.00 147.02 ?  1088 ILE Q O   1 
ATOM 2644 C CB  . ILE A 1 462 ? 140.118 111.379 83.482  1.00 147.02 ?  1088 ILE Q CB  1 
ATOM 2645 C CG1 . ILE A 1 462 ? 140.437 111.479 81.988  1.00 147.02 ?  1088 ILE Q CG1 1 
ATOM 2646 C CG2 . ILE A 1 462 ? 138.618 111.252 83.701  1.00 147.02 ?  1088 ILE Q CG2 1 
ATOM 2647 C CD1 . ILE A 1 462 ? 139.811 112.675 81.308  1.00 147.02 ?  1088 ILE Q CD1 1 
ATOM 2648 N N   . ILE A 1 463 ? 139.387 113.212 86.197  1.00 134.30 ?  1089 ILE Q N   1 
ATOM 2649 C CA  . ILE A 1 463 ? 138.989 113.218 87.599  1.00 134.30 ?  1089 ILE Q CA  1 
ATOM 2650 C C   . ILE A 1 463 ? 137.646 112.514 87.717  1.00 134.30 ?  1089 ILE Q C   1 
ATOM 2651 O O   . ILE A 1 463 ? 136.730 112.769 86.924  1.00 134.30 ?  1089 ILE Q O   1 
ATOM 2652 C CB  . ILE A 1 463 ? 138.914 114.648 88.157  1.00 134.30 ?  1089 ILE Q CB  1 
ATOM 2653 C CG1 . ILE A 1 463 ? 140.247 115.367 87.952  1.00 134.30 ?  1089 ILE Q CG1 1 
ATOM 2654 C CG2 . ILE A 1 463 ? 138.542 114.625 89.630  1.00 134.30 ?  1089 ILE Q CG2 1 
ATOM 2655 C CD1 . ILE A 1 463 ? 140.167 116.866 88.141  1.00 134.30 ?  1089 ILE Q CD1 1 
ATOM 2656 N N   . ALA A 1 464 ? 137.543 111.608 88.687  1.00 128.27 ?  1090 ALA Q N   1 
ATOM 2657 C CA  . ALA A 1 464 ? 136.319 110.856 88.955  1.00 128.27 ?  1090 ALA Q CA  1 
ATOM 2658 C C   . ALA A 1 464 ? 135.693 111.432 90.220  1.00 128.27 ?  1090 ALA Q C   1 
ATOM 2659 O O   . ALA A 1 464 ? 136.023 111.034 91.337  1.00 128.27 ?  1090 ALA Q O   1 
ATOM 2660 C CB  . ALA A 1 464 ? 136.617 109.369 89.097  1.00 128.27 ?  1090 ALA Q CB  1 
ATOM 2661 N N   . GLY A 1 465 ? 134.758 112.363 90.037  1.00 123.03 ?  1091 GLY Q N   1 
ATOM 2662 C CA  . GLY A 1 465 ? 134.199 113.112 91.149  1.00 123.03 ?  1091 GLY Q CA  1 
ATOM 2663 C C   . GLY A 1 465 ? 133.419 112.286 92.147  1.00 123.03 ?  1091 GLY Q C   1 
ATOM 2664 O O   . GLY A 1 465 ? 133.080 112.803 93.216  1.00 123.03 ?  1091 GLY Q O   1 
ATOM 2665 N N   . CYS A 1 466 ? 133.118 111.033 91.830  1.00 129.94 ?  1092 CYS Q N   1 
ATOM 2666 C CA  . CYS A 1 466 ? 132.387 110.166 92.737  1.00 129.94 ?  1092 CYS Q CA  1 
ATOM 2667 C C   . CYS A 1 466 ? 132.986 108.768 92.703  1.00 129.94 ?  1092 CYS Q C   1 
ATOM 2668 O O   . CYS A 1 466 ? 133.703 108.394 91.771  1.00 129.94 ?  1092 CYS Q O   1 
ATOM 2669 C CB  . CYS A 1 466 ? 130.895 110.112 92.389  1.00 129.94 ?  1092 CYS Q CB  1 
ATOM 2670 S SG  . CYS A 1 466 ? 129.858 109.489 93.728  1.00 129.94 ?  1092 CYS Q SG  1 
ATOM 2671 N N   . THR A 1 467 ? 132.678 107.998 93.748  1.00 145.81 ?  1093 THR Q N   1 
ATOM 2672 C CA  . THR A 1 467 ? 133.251 106.665 93.887  1.00 145.81 ?  1093 THR Q CA  1 
ATOM 2673 C C   . THR A 1 467 ? 132.753 105.710 92.809  1.00 145.81 ?  1093 THR Q C   1 
ATOM 2674 O O   . THR A 1 467 ? 133.500 104.821 92.384  1.00 145.81 ?  1093 THR Q O   1 
ATOM 2675 C CB  . THR A 1 467 ? 132.934 106.105 95.274  1.00 145.81 ?  1093 THR Q CB  1 
ATOM 2676 O OG1 . THR A 1 467 ? 133.122 107.131 96.256  1.00 145.81 ?  1093 THR Q OG1 1 
ATOM 2677 C CG2 . THR A 1 467 ? 133.845 104.931 95.597  1.00 145.81 ?  1093 THR Q CG2 1 
ATOM 2678 N N   . GLU A 1 468 ? 131.503 105.871 92.360  1.00 157.46 ?  1094 GLU Q N   1 
ATOM 2679 C CA  . GLU A 1 468 ? 130.945 104.953 91.370  1.00 157.46 ?  1094 GLU Q CA  1 
ATOM 2680 C C   . GLU A 1 468 ? 131.762 104.936 90.085  1.00 157.46 ?  1094 GLU Q C   1 
ATOM 2681 O O   . GLU A 1 468 ? 131.881 103.887 89.442  1.00 157.46 ?  1094 GLU Q O   1 
ATOM 2682 C CB  . GLU A 1 468 ? 129.491 105.315 91.065  1.00 157.46 ?  1094 GLU Q CB  1 
ATOM 2683 C CG  . GLU A 1 468 ? 128.476 104.701 92.018  1.00 157.46 ?  1094 GLU Q CG  1 
ATOM 2684 C CD  . GLU A 1 468 ? 128.502 105.332 93.394  1.00 157.46 ?  1094 GLU Q CD  1 
ATOM 2685 O OE1 . GLU A 1 468 ? 128.757 106.550 93.486  1.00 157.46 ?  1094 GLU Q OE1 1 
ATOM 2686 O OE2 . GLU A 1 468 ? 128.265 104.609 94.385  1.00 157.46 -1 1094 GLU Q OE2 1 
ATOM 2687 N N   . VAL A 1 469 ? 132.321 106.081 89.689  1.00 154.41 ?  1095 VAL Q N   1 
ATOM 2688 C CA  . VAL A 1 469 ? 133.184 106.106 88.514  1.00 154.41 ?  1095 VAL Q CA  1 
ATOM 2689 C C   . VAL A 1 469 ? 134.441 105.282 88.760  1.00 154.41 ?  1095 VAL Q C   1 
ATOM 2690 O O   . VAL A 1 469 ? 134.881 104.519 87.892  1.00 154.41 ?  1095 VAL Q O   1 
ATOM 2691 C CB  . VAL A 1 469 ? 133.521 107.556 88.125  1.00 154.41 ?  1095 VAL Q CB  1 
ATOM 2692 C CG1 . VAL A 1 469 ? 134.389 107.578 86.876  1.00 154.41 ?  1095 VAL Q CG1 1 
ATOM 2693 C CG2 . VAL A 1 469 ? 132.247 108.357 87.909  1.00 154.41 ?  1095 VAL Q CG2 1 
ATOM 2694 N N   . SER A 1 470 ? 135.036 105.416 89.948  1.00 154.50 ?  1096 SER Q N   1 
ATOM 2695 C CA  . SER A 1 470 ? 136.236 104.650 90.266  1.00 154.50 ?  1096 SER Q CA  1 
ATOM 2696 C C   . SER A 1 470 ? 135.942 103.159 90.371  1.00 154.50 ?  1096 SER Q C   1 
ATOM 2697 O O   . SER A 1 470 ? 136.843 102.336 90.176  1.00 154.50 ?  1096 SER Q O   1 
ATOM 2698 C CB  . SER A 1 470 ? 136.850 105.161 91.568  1.00 154.50 ?  1096 SER Q CB  1 
ATOM 2699 O OG  . SER A 1 470 ? 137.118 106.550 91.493  1.00 154.50 ?  1096 SER Q OG  1 
ATOM 2700 N N   . VAL A 1 471 ? 134.694 102.798 90.680  1.00 160.14 ?  1097 VAL Q N   1 
ATOM 2701 C CA  . VAL A 1 471 ? 134.345 101.392 90.870  1.00 160.14 ?  1097 VAL Q CA  1 
ATOM 2702 C C   . VAL A 1 471 ? 134.546 100.604 89.582  1.00 160.14 ?  1097 VAL Q C   1 
ATOM 2703 O O   . VAL A 1 471 ? 135.101 99.499  89.593  1.00 160.14 ?  1097 VAL Q O   1 
ATOM 2704 C CB  . VAL A 1 471 ? 132.899 101.269 91.390  1.00 160.14 ?  1097 VAL Q CB  1 
ATOM 2705 C CG1 . VAL A 1 471 ? 132.387 99.845  91.219  1.00 160.14 ?  1097 VAL Q CG1 1 
ATOM 2706 C CG2 . VAL A 1 471 ? 132.822 101.691 92.848  1.00 160.14 ?  1097 VAL Q CG2 1 
ATOM 2707 N N   . VAL A 1 472 ? 134.106 101.157 88.453  1.00 163.90 ?  1098 VAL Q N   1 
ATOM 2708 C CA  . VAL A 1 472 ? 134.138 100.442 87.180  1.00 163.90 ?  1098 VAL Q CA  1 
ATOM 2709 C C   . VAL A 1 472 ? 135.249 100.914 86.256  1.00 163.90 ?  1098 VAL Q C   1 
ATOM 2710 O O   . VAL A 1 472 ? 135.492 100.260 85.228  1.00 163.90 ?  1098 VAL Q O   1 
ATOM 2711 C CB  . VAL A 1 472 ? 132.780 100.529 86.451  1.00 163.90 ?  1098 VAL Q CB  1 
ATOM 2712 C CG1 . VAL A 1 472 ? 131.693 99.854  87.272  1.00 163.90 ?  1098 VAL Q CG1 1 
ATOM 2713 C CG2 . VAL A 1 472 ? 132.423 101.978 86.171  1.00 163.90 ?  1098 VAL Q CG2 1 
ATOM 2714 N N   . LEU A 1 473 ? 135.927 102.013 86.573  1.00 160.66 ?  1099 LEU Q N   1 
ATOM 2715 C CA  . LEU A 1 473 ? 136.983 102.554 85.728  1.00 160.66 ?  1099 LEU Q CA  1 
ATOM 2716 C C   . LEU A 1 473 ? 138.292 102.570 86.505  1.00 160.66 ?  1099 LEU Q C   1 
ATOM 2717 O O   . LEU A 1 473 ? 138.338 103.057 87.639  1.00 160.66 ?  1099 LEU Q O   1 
ATOM 2718 C CB  . LEU A 1 473 ? 136.626 103.961 85.244  1.00 160.66 ?  1099 LEU Q CB  1 
ATOM 2719 C CG  . LEU A 1 473 ? 137.491 104.563 84.135  1.00 160.66 ?  1099 LEU Q CG  1 
ATOM 2720 C CD1 . LEU A 1 473 ? 137.331 103.776 82.843  1.00 160.66 ?  1099 LEU Q CD1 1 
ATOM 2721 C CD2 . LEU A 1 473 ? 137.142 106.028 83.920  1.00 160.66 ?  1099 LEU Q CD2 1 
ATOM 2722 N N   . LYS A 1 474 ? 139.345 102.034 85.896  1.00 154.78 ?  1100 LYS Q N   1 
ATOM 2723 C CA  . LYS A 1 474 ? 140.663 101.931 86.510  1.00 154.78 ?  1100 LYS Q CA  1 
ATOM 2724 C C   . LYS A 1 474 ? 141.702 102.621 85.632  1.00 154.78 ?  1100 LYS Q C   1 
ATOM 2725 O O   . LYS A 1 474 ? 141.398 103.140 84.555  1.00 154.78 ?  1100 LYS Q O   1 
ATOM 2726 C CB  . LYS A 1 474 ? 141.043 100.466 86.751  1.00 154.78 ?  1100 LYS Q CB  1 
ATOM 2727 C CG  . LYS A 1 474 ? 139.930 99.631  87.355  1.00 154.78 ?  1100 LYS Q CG  1 
ATOM 2728 C CD  . LYS A 1 474 ? 139.480 100.206 88.686  1.00 154.78 ?  1100 LYS Q CD  1 
ATOM 2729 C CE  . LYS A 1 474 ? 138.258 99.480  89.212  1.00 154.78 ?  1100 LYS Q CE  1 
ATOM 2730 N NZ  . LYS A 1 474 ? 137.864 99.968  90.560  1.00 154.78 1  1100 LYS Q NZ  1 
ATOM 2731 N N   . GLN A 1 475 ? 142.948 102.617 86.112  1.00 152.03 ?  1101 GLN Q N   1 
ATOM 2732 C CA  . GLN A 1 475 ? 144.024 103.304 85.405  1.00 152.03 ?  1101 GLN Q CA  1 
ATOM 2733 C C   . GLN A 1 475 ? 144.321 102.654 84.059  1.00 152.03 ?  1101 GLN Q C   1 
ATOM 2734 O O   . GLN A 1 475 ? 144.596 103.351 83.075  1.00 152.03 ?  1101 GLN Q O   1 
ATOM 2735 C CB  . GLN A 1 475 ? 145.283 103.330 86.269  1.00 152.03 ?  1101 GLN Q CB  1 
ATOM 2736 C CG  . GLN A 1 475 ? 146.438 104.078 85.638  1.00 152.03 ?  1101 GLN Q CG  1 
ATOM 2737 C CD  . GLN A 1 475 ? 146.031 105.449 85.150  1.00 152.03 ?  1101 GLN Q CD  1 
ATOM 2738 O OE1 . GLN A 1 475 ? 145.866 106.372 85.943  1.00 152.03 ?  1101 GLN Q OE1 1 
ATOM 2739 N NE2 . GLN A 1 475 ? 145.874 105.593 83.839  1.00 152.03 ?  1101 GLN Q NE2 1 
ATOM 2740 N N   . ASP A 1 476 ? 144.276 101.322 83.999  1.00 162.00 ?  1102 ASP Q N   1 
ATOM 2741 C CA  . ASP A 1 476 ? 144.640 100.612 82.778  1.00 162.00 ?  1102 ASP Q CA  1 
ATOM 2742 C C   . ASP A 1 476 ? 143.709 100.929 81.617  1.00 162.00 ?  1102 ASP Q C   1 
ATOM 2743 O O   . ASP A 1 476 ? 144.091 100.730 80.458  1.00 162.00 ?  1102 ASP Q O   1 
ATOM 2744 C CB  . ASP A 1 476 ? 144.654 99.104  83.035  1.00 162.00 ?  1102 ASP Q CB  1 
ATOM 2745 C CG  . ASP A 1 476 ? 143.318 98.585  83.535  1.00 162.00 ?  1102 ASP Q CG  1 
ATOM 2746 O OD1 . ASP A 1 476 ? 142.469 99.408  83.939  1.00 162.00 ?  1102 ASP Q OD1 1 
ATOM 2747 O OD2 . ASP A 1 476 ? 143.117 97.352  83.523  1.00 162.00 -1 1102 ASP Q OD2 1 
ATOM 2748 N N   . ASP A 1 477 ? 142.501 101.418 81.895  1.00 164.91 ?  1103 ASP Q N   1 
ATOM 2749 C CA  . ASP A 1 477 ? 141.546 101.720 80.840  1.00 164.91 ?  1103 ASP Q CA  1 
ATOM 2750 C C   . ASP A 1 477 ? 141.815 103.052 80.156  1.00 164.91 ?  1103 ASP Q C   1 
ATOM 2751 O O   . ASP A 1 477 ? 141.167 103.352 79.147  1.00 164.91 ?  1103 ASP Q O   1 
ATOM 2752 C CB  . ASP A 1 477 ? 140.123 101.713 81.405  1.00 164.91 ?  1103 ASP Q CB  1 
ATOM 2753 C CG  . ASP A 1 477 ? 139.694 100.340 81.882  1.00 164.91 ?  1103 ASP Q CG  1 
ATOM 2754 O OD1 . ASP A 1 477 ? 139.804 99.375  81.096  1.00 164.91 ?  1103 ASP Q OD1 1 
ATOM 2755 O OD2 . ASP A 1 477 ? 139.248 100.224 83.044  1.00 164.91 -1 1103 ASP Q OD2 1 
ATOM 2756 N N   . LEU A 1 478 ? 142.746 103.853 80.668  1.00 156.03 ?  1104 LEU Q N   1 
ATOM 2757 C CA  . LEU A 1 478 ? 143.037 105.161 80.104  1.00 156.03 ?  1104 LEU Q CA  1 
ATOM 2758 C C   . LEU A 1 478 ? 144.537 105.329 79.914  1.00 156.03 ?  1104 LEU Q C   1 
ATOM 2759 O O   . LEU A 1 478 ? 145.339 104.897 80.746  1.00 156.03 ?  1104 LEU Q O   1 
ATOM 2760 C CB  . LEU A 1 478 ? 142.503 106.292 80.995  1.00 156.03 ?  1104 LEU Q CB  1 
ATOM 2761 C CG  . LEU A 1 478 ? 141.009 106.266 81.319  1.00 156.03 ?  1104 LEU Q CG  1 
ATOM 2762 C CD1 . LEU A 1 478 ? 140.692 107.212 82.467  1.00 156.03 ?  1104 LEU Q CD1 1 
ATOM 2763 C CD2 . LEU A 1 478 ? 140.192 106.617 80.086  1.00 156.03 ?  1104 LEU Q CD2 1 
ATOM 2764 N N   . LYS A 1 479 ? 144.905 105.968 78.803  1.00 146.51 ?  1105 LYS Q N   1 
ATOM 2765 C CA  . LYS A 1 479 ? 146.299 106.329 78.581  1.00 146.51 ?  1105 LYS Q CA  1 
ATOM 2766 C C   . LYS A 1 479 ? 146.760 107.408 79.550  1.00 146.51 ?  1105 LYS Q C   1 
ATOM 2767 O O   . LYS A 1 479 ? 147.899 107.361 80.028  1.00 146.51 ?  1105 LYS Q O   1 
ATOM 2768 C CB  . LYS A 1 479 ? 146.497 106.807 77.142  1.00 146.51 ?  1105 LYS Q CB  1 
ATOM 2769 C CG  . LYS A 1 479 ? 145.731 106.004 76.106  1.00 146.51 ?  1105 LYS Q CG  1 
ATOM 2770 C CD  . LYS A 1 479 ? 145.709 106.725 74.768  1.00 146.51 ?  1105 LYS Q CD  1 
ATOM 2771 C CE  . LYS A 1 479 ? 144.770 106.044 73.788  1.00 146.51 ?  1105 LYS Q CE  1 
ATOM 2772 N NZ  . LYS A 1 479 ? 145.299 104.729 73.335  1.00 146.51 1  1105 LYS Q NZ  1 
ATOM 2773 N N   . VAL A 1 480 ? 145.898 108.374 79.849  1.00 148.48 ?  1106 VAL Q N   1 
ATOM 2774 C CA  . VAL A 1 480 ? 146.220 109.454 80.776  1.00 148.48 ?  1106 VAL Q CA  1 
ATOM 2775 C C   . VAL A 1 480 ? 146.034 108.939 82.198  1.00 148.48 ?  1106 VAL Q C   1 
ATOM 2776 O O   . VAL A 1 480 ? 145.320 107.946 82.406  1.00 148.48 ?  1106 VAL Q O   1 
ATOM 2777 C CB  . VAL A 1 480 ? 145.351 110.694 80.509  1.00 148.48 ?  1106 VAL Q CB  1 
ATOM 2778 C CG1 . VAL A 1 480 ? 145.629 111.242 79.118  1.00 148.48 ?  1106 VAL Q CG1 1 
ATOM 2779 C CG2 . VAL A 1 480 ? 143.876 110.360 80.679  1.00 148.48 ?  1106 VAL Q CG2 1 
ATOM 2780 N N   . PRO A 1 481 ? 146.665 109.555 83.196  1.00 147.42 ?  1107 PRO Q N   1 
ATOM 2781 C CA  . PRO A 1 481 ? 146.466 109.104 84.577  1.00 147.42 ?  1107 PRO Q CA  1 
ATOM 2782 C C   . PRO A 1 481 ? 145.013 109.241 85.010  1.00 147.42 ?  1107 PRO Q C   1 
ATOM 2783 O O   . PRO A 1 481 ? 144.319 110.189 84.637  1.00 147.42 ?  1107 PRO Q O   1 
ATOM 2784 C CB  . PRO A 1 481 ? 147.382 110.029 85.386  1.00 147.42 ?  1107 PRO Q CB  1 
ATOM 2785 C CG  . PRO A 1 481 ? 148.414 110.480 84.411  1.00 147.42 ?  1107 PRO Q CG  1 
ATOM 2786 C CD  . PRO A 1 481 ? 147.687 110.612 83.108  1.00 147.42 ?  1107 PRO Q CD  1 
ATOM 2787 N N   . LEU A 1 482 ? 144.556 108.273 85.798  1.00 150.72 ?  1108 LEU Q N   1 
ATOM 2788 C CA  . LEU A 1 482 ? 143.253 108.328 86.446  1.00 150.72 ?  1108 LEU Q CA  1 
ATOM 2789 C C   . LEU A 1 482 ? 143.473 108.693 87.907  1.00 150.72 ?  1108 LEU Q C   1 
ATOM 2790 O O   . LEU A 1 482 ? 144.171 107.976 88.631  1.00 150.72 ?  1108 LEU Q O   1 
ATOM 2791 C CB  . LEU A 1 482 ? 142.516 106.994 86.319  1.00 150.72 ?  1108 LEU Q CB  1 
ATOM 2792 C CG  . LEU A 1 482 ? 141.058 106.921 86.784  1.00 150.72 ?  1108 LEU Q CG  1 
ATOM 2793 C CD1 . LEU A 1 482 ? 140.323 105.855 85.997  1.00 150.72 ?  1108 LEU Q CD1 1 
ATOM 2794 C CD2 . LEU A 1 482 ? 140.945 106.633 88.276  1.00 150.72 ?  1108 LEU Q CD2 1 
ATOM 2795 N N   . ILE A 1 483 ? 142.871 109.797 88.338  1.00 148.97 ?  1109 ILE Q N   1 
ATOM 2796 C CA  . ILE A 1 483 ? 143.052 110.325 89.683  1.00 148.97 ?  1109 ILE Q CA  1 
ATOM 2797 C C   . ILE A 1 483 ? 141.685 110.458 90.334  1.00 148.97 ?  1109 ILE Q C   1 
ATOM 2798 O O   . ILE A 1 483 ? 140.719 110.879 89.689  1.00 148.97 ?  1109 ILE Q O   1 
ATOM 2799 C CB  . ILE A 1 483 ? 143.783 111.684 89.676  1.00 148.97 ?  1109 ILE Q CB  1 
ATOM 2800 C CG1 . ILE A 1 483 ? 144.861 111.713 88.591  1.00 148.97 ?  1109 ILE Q CG1 1 
ATOM 2801 C CG2 . ILE A 1 483 ? 144.395 111.964 91.038  1.00 148.97 ?  1109 ILE Q CG2 1 
ATOM 2802 C CD1 . ILE A 1 483 ? 145.276 113.110 88.180  1.00 148.97 ?  1109 ILE Q CD1 1 
ATOM 2803 N N   . ASP A 1 484 ? 141.605 110.095 91.609  1.00 147.80 ?  1110 ASP Q N   1 
ATOM 2804 C CA  . ASP A 1 484 ? 140.350 110.150 92.338  1.00 147.80 ?  1110 ASP Q CA  1 
ATOM 2805 C C   . ASP A 1 484 ? 140.543 110.865 93.666  1.00 147.80 ?  1110 ASP Q C   1 
ATOM 2806 O O   . ASP A 1 484 ? 141.645 110.866 94.224  1.00 147.80 ?  1110 ASP Q O   1 
ATOM 2807 C CB  . ASP A 1 484 ? 139.797 108.739 92.592  1.00 147.80 ?  1110 ASP Q CB  1 
ATOM 2808 C CG  . ASP A 1 484 ? 140.856 107.778 93.094  1.00 147.80 ?  1110 ASP Q CG  1 
ATOM 2809 O OD1 . ASP A 1 484 ? 142.026 108.194 93.225  1.00 147.80 ?  1110 ASP Q OD1 1 
ATOM 2810 O OD2 . ASP A 1 484 ? 140.518 106.606 93.361  1.00 147.80 -1 1110 ASP Q OD2 1 
ATOM 2811 N N   . PRO A 1 485 ? 139.485 111.498 94.192  1.00 130.57 ?  1111 PRO Q N   1 
ATOM 2812 C CA  . PRO A 1 485 ? 139.524 112.107 95.523  1.00 130.57 ?  1111 PRO Q CA  1 
ATOM 2813 C C   . PRO A 1 485 ? 139.720 111.065 96.618  1.00 130.57 ?  1111 PRO Q C   1 
ATOM 2814 O O   . PRO A 1 485 ? 140.425 111.296 97.600  1.00 130.57 ?  1111 PRO Q O   1 
ATOM 2815 C CB  . PRO A 1 485 ? 138.151 112.774 95.643  1.00 130.57 ?  1111 PRO Q CB  1 
ATOM 2816 C CG  . PRO A 1 485 ? 137.715 112.993 94.235  1.00 130.57 ?  1111 PRO Q CG  1 
ATOM 2817 C CD  . PRO A 1 485 ? 138.224 111.797 93.495  1.00 130.57 ?  1111 PRO Q CD  1 
ATOM 2818 O OXT . PRO A 1 485 ? 139.182 109.962 96.544  1.00 130.57 -1 1111 PRO Q OXT 1 
ATOM 2819 N N   . ALA B 1 59  ? 110.658 92.348  160.783 1.00 132.01 ?  35   ALA R N   1 
ATOM 2820 C CA  . ALA B 1 59  ? 110.937 93.470  159.896 1.00 132.01 ?  35   ALA R CA  1 
ATOM 2821 C C   . ALA B 1 59  ? 109.944 93.510  158.740 1.00 132.01 ?  35   ALA R C   1 
ATOM 2822 O O   . ALA B 1 59  ? 110.232 93.012  157.652 1.00 132.01 ?  35   ALA R O   1 
ATOM 2823 C CB  . ALA B 1 59  ? 112.360 93.388  159.371 1.00 132.01 ?  35   ALA R CB  1 
ATOM 2824 N N   . PRO B 1 60  ? 108.777 94.101  158.973 1.00 130.79 ?  36   PRO R N   1 
ATOM 2825 C CA  . PRO B 1 60  ? 107.766 94.184  157.917 1.00 130.79 ?  36   PRO R CA  1 
ATOM 2826 C C   . PRO B 1 60  ? 108.025 95.348  156.974 1.00 130.79 ?  36   PRO R C   1 
ATOM 2827 O O   . PRO B 1 60  ? 108.664 96.342  157.326 1.00 130.79 ?  36   PRO R O   1 
ATOM 2828 C CB  . PRO B 1 60  ? 106.462 94.385  158.696 1.00 130.79 ?  36   PRO R CB  1 
ATOM 2829 C CG  . PRO B 1 60  ? 106.879 95.036  159.987 1.00 130.79 ?  36   PRO R CG  1 
ATOM 2830 C CD  . PRO B 1 60  ? 108.353 94.789  160.205 1.00 130.79 ?  36   PRO R CD  1 
ATOM 2831 N N   . LEU B 1 61  ? 107.514 95.208  155.753 1.00 120.47 ?  37   LEU R N   1 
ATOM 2832 C CA  . LEU B 1 61  ? 107.659 96.252  154.747 1.00 120.47 ?  37   LEU R CA  1 
ATOM 2833 C C   . LEU B 1 61  ? 106.502 97.235  154.854 1.00 120.47 ?  37   LEU R C   1 
ATOM 2834 O O   . LEU B 1 61  ? 105.340 96.813  154.792 1.00 120.47 ?  37   LEU R O   1 
ATOM 2835 C CB  . LEU B 1 61  ? 107.711 95.654  153.353 1.00 120.47 ?  37   LEU R CB  1 
ATOM 2836 C CG  . LEU B 1 61  ? 109.111 95.285  152.857 1.00 120.47 ?  37   LEU R CG  1 
ATOM 2837 C CD1 . LEU B 1 61  ? 109.093 94.987  151.369 1.00 120.47 ?  37   LEU R CD1 1 
ATOM 2838 C CD2 . LEU B 1 61  ? 110.109 96.390  153.173 1.00 120.47 ?  37   LEU R CD2 1 
ATOM 2839 N N   . PRO B 1 62  ? 106.766 98.530  155.029 1.00 110.57 ?  38   PRO R N   1 
ATOM 2840 C CA  . PRO B 1 62  ? 105.670 99.498  155.172 1.00 110.57 ?  38   PRO R CA  1 
ATOM 2841 C C   . PRO B 1 62  ? 104.760 99.510  153.955 1.00 110.57 ?  38   PRO R C   1 
ATOM 2842 O O   . PRO B 1 62  ? 105.193 99.296  152.821 1.00 110.57 ?  38   PRO R O   1 
ATOM 2843 C CB  . PRO B 1 62  ? 106.388 100.843 155.334 1.00 110.57 ?  38   PRO R CB  1 
ATOM 2844 C CG  . PRO B 1 62  ? 107.843 100.553 155.434 1.00 110.57 ?  38   PRO R CG  1 
ATOM 2845 C CD  . PRO B 1 62  ? 108.080 99.087  155.383 1.00 110.57 ?  38   PRO R CD  1 
ATOM 2846 N N   . SER B 1 63  ? 103.482 99.762  154.207 1.00 116.89 ?  39   SER R N   1 
ATOM 2847 C CA  . SER B 1 63  ? 102.506 99.821  153.127 1.00 116.89 ?  39   SER R CA  1 
ATOM 2848 C C   . SER B 1 63  ? 102.756 101.057 152.270 1.00 116.89 ?  39   SER R C   1 
ATOM 2849 O O   . SER B 1 63  ? 102.799 102.174 152.798 1.00 116.89 ?  39   SER R O   1 
ATOM 2850 C CB  . SER B 1 63  ? 101.088 99.845  153.691 1.00 116.89 ?  39   SER R CB  1 
ATOM 2851 O OG  . SER B 1 63  ? 100.836 101.053 154.388 1.00 116.89 ?  39   SER R OG  1 
ATOM 2852 N N   . PRO B 1 64  ? 102.929 100.903 150.961 1.00 115.24 ?  40   PRO R N   1 
ATOM 2853 C CA  . PRO B 1 64  ? 103.235 102.061 150.115 1.00 115.24 ?  40   PRO R CA  1 
ATOM 2854 C C   . PRO B 1 64  ? 102.058 103.016 149.990 1.00 115.24 ?  40   PRO R C   1 
ATOM 2855 O O   . PRO B 1 64  ? 100.895 102.638 150.150 1.00 115.24 ?  40   PRO R O   1 
ATOM 2856 C CB  . PRO B 1 64  ? 103.578 101.427 148.762 1.00 115.24 ?  40   PRO R CB  1 
ATOM 2857 C CG  . PRO B 1 64  ? 103.934 100.002 149.084 1.00 115.24 ?  40   PRO R CG  1 
ATOM 2858 C CD  . PRO B 1 64  ? 103.047 99.635  150.226 1.00 115.24 ?  40   PRO R CD  1 
ATOM 2859 N N   . LYS B 1 65  ? 102.382 104.275 149.702 1.00 115.99 ?  41   LYS R N   1 
ATOM 2860 C CA  . LYS B 1 65  ? 101.375 105.291 149.442 1.00 115.99 ?  41   LYS R CA  1 
ATOM 2861 C C   . LYS B 1 65  ? 100.785 105.088 148.042 1.00 115.99 ?  41   LYS R C   1 
ATOM 2862 O O   . LYS B 1 65  ? 101.336 104.367 147.205 1.00 115.99 ?  41   LYS R O   1 
ATOM 2863 C CB  . LYS B 1 65  ? 101.994 106.684 149.589 1.00 115.99 ?  41   LYS R CB  1 
ATOM 2864 C CG  . LYS B 1 65  ? 101.031 107.871 149.529 1.00 115.99 ?  41   LYS R CG  1 
ATOM 2865 C CD  . LYS B 1 65  ? 99.740  107.626 150.303 1.00 115.99 ?  41   LYS R CD  1 
ATOM 2866 C CE  . LYS B 1 65  ? 99.994  107.508 151.800 1.00 115.99 ?  41   LYS R CE  1 
ATOM 2867 N NZ  . LYS B 1 65  ? 98.792  107.020 152.530 1.00 115.99 1  41   LYS R NZ  1 
ATOM 2868 N N   . ALA B 1 66  ? 99.638  105.729 147.792 1.00 118.64 ?  42   ALA R N   1 
ATOM 2869 C CA  . ALA B 1 66  ? 98.931  105.539 146.528 1.00 118.64 ?  42   ALA R CA  1 
ATOM 2870 C C   . ALA B 1 66  ? 99.750  106.011 145.332 1.00 118.64 ?  42   ALA R C   1 
ATOM 2871 O O   . ALA B 1 66  ? 99.552  105.524 144.211 1.00 118.64 ?  42   ALA R O   1 
ATOM 2872 C CB  . ALA B 1 66  ? 97.586  106.265 146.566 1.00 118.64 ?  42   ALA R CB  1 
ATOM 2873 N N   . TRP B 1 67  ? 100.665 106.960 145.536 1.00 115.07 ?  43   TRP R N   1 
ATOM 2874 C CA  . TRP B 1 67  ? 101.540 107.349 144.439 1.00 115.07 ?  43   TRP R CA  1 
ATOM 2875 C C   . TRP B 1 67  ? 102.356 106.172 143.926 1.00 115.07 ?  43   TRP R C   1 
ATOM 2876 O O   . TRP B 1 67  ? 102.665 106.117 142.730 1.00 115.07 ?  43   TRP R O   1 
ATOM 2877 C CB  . TRP B 1 67  ? 102.465 108.482 144.872 1.00 115.07 ?  43   TRP R CB  1 
ATOM 2878 C CG  . TRP B 1 67  ? 101.754 109.741 145.226 1.00 115.07 ?  43   TRP R CG  1 
ATOM 2879 C CD1 . TRP B 1 67  ? 100.806 110.382 144.485 1.00 115.07 ?  43   TRP R CD1 1 
ATOM 2880 C CD2 . TRP B 1 67  ? 101.950 110.536 146.400 1.00 115.07 ?  43   TRP R CD2 1 
ATOM 2881 N NE1 . TRP B 1 67  ? 100.388 111.519 145.131 1.00 115.07 ?  43   TRP R NE1 1 
ATOM 2882 C CE2 . TRP B 1 67  ? 101.077 111.637 146.309 1.00 115.07 ?  43   TRP R CE2 1 
ATOM 2883 C CE3 . TRP B 1 67  ? 102.775 110.419 147.522 1.00 115.07 ?  43   TRP R CE3 1 
ATOM 2884 C CZ2 . TRP B 1 67  ? 101.004 112.615 147.298 1.00 115.07 ?  43   TRP R CZ2 1 
ATOM 2885 C CZ3 . TRP B 1 67  ? 102.701 111.392 148.503 1.00 115.07 ?  43   TRP R CZ3 1 
ATOM 2886 C CH2 . TRP B 1 67  ? 101.822 112.476 148.384 1.00 115.07 ?  43   TRP R CH2 1 
ATOM 2887 N N   . ASP B 1 68  ? 102.693 105.222 144.800 1.00 116.50 ?  44   ASP R N   1 
ATOM 2888 C CA  . ASP B 1 68  ? 103.426 104.046 144.353 1.00 116.50 ?  44   ASP R CA  1 
ATOM 2889 C C   . ASP B 1 68  ? 102.608 103.230 143.360 1.00 116.50 ?  44   ASP R C   1 
ATOM 2890 O O   . ASP B 1 68  ? 103.124 102.818 142.314 1.00 116.50 ?  44   ASP R O   1 
ATOM 2891 C CB  . ASP B 1 68  ? 103.828 103.190 145.553 1.00 116.50 ?  44   ASP R CB  1 
ATOM 2892 C CG  . ASP B 1 68  ? 105.157 102.489 145.349 1.00 116.50 ?  44   ASP R CG  1 
ATOM 2893 O OD1 . ASP B 1 68  ? 105.697 102.554 144.225 1.00 116.50 ?  44   ASP R OD1 1 
ATOM 2894 O OD2 . ASP B 1 68  ? 105.662 101.874 146.311 1.00 116.50 -1 44   ASP R OD2 1 
ATOM 2895 N N   . VAL B 1 69  ? 101.329 102.989 143.658 1.00 119.48 ?  45   VAL R N   1 
ATOM 2896 C CA  . VAL B 1 69  ? 100.528 102.205 142.724 1.00 119.48 ?  45   VAL R CA  1 
ATOM 2897 C C   . VAL B 1 69  ? 100.244 103.014 141.464 1.00 119.48 ?  45   VAL R C   1 
ATOM 2898 O O   . VAL B 1 69  ? 100.087 102.445 140.377 1.00 119.48 ?  45   VAL R O   1 
ATOM 2899 C CB  . VAL B 1 69  ? 99.235  101.683 143.388 1.00 119.48 ?  45   VAL R CB  1 
ATOM 2900 C CG1 . VAL B 1 69  ? 98.348  102.815 143.860 1.00 119.48 ?  45   VAL R CG1 1 
ATOM 2901 C CG2 . VAL B 1 69  ? 98.475  100.755 142.445 1.00 119.48 ?  45   VAL R CG2 1 
ATOM 2902 N N   . VAL B 1 70  ? 100.199 104.346 141.570 1.00 114.39 ?  46   VAL R N   1 
ATOM 2903 C CA  . VAL B 1 70  ? 100.101 105.165 140.362 1.00 114.39 ?  46   VAL R CA  1 
ATOM 2904 C C   . VAL B 1 70  ? 101.313 104.938 139.466 1.00 114.39 ?  46   VAL R C   1 
ATOM 2905 O O   . VAL B 1 70  ? 101.183 104.744 138.248 1.00 114.39 ?  46   VAL R O   1 
ATOM 2906 C CB  . VAL B 1 70  ? 99.941  106.652 140.731 1.00 114.39 ?  46   VAL R CB  1 
ATOM 2907 C CG1 . VAL B 1 70  ? 99.982  107.515 139.480 1.00 114.39 ?  46   VAL R CG1 1 
ATOM 2908 C CG2 . VAL B 1 70  ? 98.638  106.874 141.481 1.00 114.39 ?  46   VAL R CG2 1 
ATOM 2909 N N   . LEU B 1 71  ? 102.508 104.948 140.058 1.00 113.33 ?  47   LEU R N   1 
ATOM 2910 C CA  . LEU B 1 71  ? 103.721 104.688 139.288 1.00 113.33 ?  47   LEU R CA  1 
ATOM 2911 C C   . LEU B 1 71  ? 103.708 103.286 138.695 1.00 113.33 ?  47   LEU R C   1 
ATOM 2912 O O   . LEU B 1 71  ? 104.148 103.079 137.559 1.00 113.33 ?  47   LEU R O   1 
ATOM 2913 C CB  . LEU B 1 71  ? 104.953 104.886 140.170 1.00 113.33 ?  47   LEU R CB  1 
ATOM 2914 C CG  . LEU B 1 71  ? 105.687 106.219 140.042 1.00 113.33 ?  47   LEU R CG  1 
ATOM 2915 C CD1 . LEU B 1 71  ? 107.108 106.091 140.558 1.00 113.33 ?  47   LEU R CD1 1 
ATOM 2916 C CD2 . LEU B 1 71  ? 105.691 106.679 138.598 1.00 113.33 ?  47   LEU R CD2 1 
ATOM 2917 N N   . CYS B 1 72  ? 103.218 102.308 139.457 1.00 114.80 ?  48   CYS R N   1 
ATOM 2918 C CA  . CYS B 1 72  ? 103.137 100.943 138.947 1.00 114.80 ?  48   CYS R CA  1 
ATOM 2919 C C   . CYS B 1 72  ? 102.212 100.861 137.741 1.00 114.80 ?  48   CYS R C   1 
ATOM 2920 O O   . CYS B 1 72  ? 102.527 100.190 136.750 1.00 114.80 ?  48   CYS R O   1 
ATOM 2921 C CB  . CYS B 1 72  ? 102.660 99.997  140.046 1.00 114.80 ?  48   CYS R CB  1 
ATOM 2922 S SG  . CYS B 1 72  ? 102.012 98.418  139.447 1.00 114.80 ?  48   CYS R SG  1 
ATOM 2923 N N   . ILE B 1 73  ? 101.062 101.534 137.810 1.00 111.51 ?  49   ILE R N   1 
ATOM 2924 C CA  . ILE B 1 73  ? 100.129 101.537 136.686 1.00 111.51 ?  49   ILE R CA  1 
ATOM 2925 C C   . ILE B 1 73  ? 100.774 102.177 135.466 1.00 111.51 ?  49   ILE R C   1 
ATOM 2926 O O   . ILE B 1 73  ? 100.669 101.662 134.343 1.00 111.51 ?  49   ILE R O   1 
ATOM 2927 C CB  . ILE B 1 73  ? 98.824  102.253 137.080 1.00 111.51 ?  49   ILE R CB  1 
ATOM 2928 C CG1 . ILE B 1 73  ? 98.003  101.381 138.032 1.00 111.51 ?  49   ILE R CG1 1 
ATOM 2929 C CG2 . ILE B 1 73  ? 98.011  102.608 135.845 1.00 111.51 ?  49   ILE R CG2 1 
ATOM 2930 C CD1 . ILE B 1 73  ? 97.667  100.015 137.473 1.00 111.51 ?  49   ILE R CD1 1 
ATOM 2931 N N   . SER B 1 74  ? 101.459 103.306 135.667 1.00 111.26 ?  50   SER R N   1 
ATOM 2932 C CA  . SER B 1 74  ? 102.119 103.971 134.549 1.00 111.26 ?  50   SER R CA  1 
ATOM 2933 C C   . SER B 1 74  ? 103.172 103.070 133.914 1.00 111.26 ?  50   SER R C   1 
ATOM 2934 O O   . SER B 1 74  ? 103.251 102.965 132.683 1.00 111.26 ?  50   SER R O   1 
ATOM 2935 C CB  . SER B 1 74  ? 102.747 105.284 135.016 1.00 111.26 ?  50   SER R CB  1 
ATOM 2936 O OG  . SER B 1 74  ? 103.374 105.960 133.940 1.00 111.26 ?  50   SER R OG  1 
ATOM 2937 N N   . GLY B 1 75  ? 103.982 102.404 134.737 1.00 106.13 ?  51   GLY R N   1 
ATOM 2938 C CA  . GLY B 1 75  ? 105.007 101.526 134.198 1.00 106.13 ?  51   GLY R CA  1 
ATOM 2939 C C   . GLY B 1 75  ? 104.427 100.336 133.458 1.00 106.13 ?  51   GLY R C   1 
ATOM 2940 O O   . GLY B 1 75  ? 104.940 99.932  132.410 1.00 106.13 ?  51   GLY R O   1 
ATOM 2941 N N   . THR B 1 76  ? 103.356 99.753  133.998 1.00 107.52 ?  52   THR R N   1 
ATOM 2942 C CA  . THR B 1 76  ? 102.713 98.633  133.324 1.00 107.52 ?  52   THR R CA  1 
ATOM 2943 C C   . THR B 1 76  ? 102.168 99.058  131.969 1.00 107.52 ?  52   THR R C   1 
ATOM 2944 O O   . THR B 1 76  ? 102.331 98.342  130.972 1.00 107.52 ?  52   THR R O   1 
ATOM 2945 C CB  . THR B 1 76  ? 101.594 98.065  134.196 1.00 107.52 ?  52   THR R CB  1 
ATOM 2946 O OG1 . THR B 1 76  ? 102.024 98.026  135.562 1.00 107.52 ?  52   THR R OG1 1 
ATOM 2947 C CG2 . THR B 1 76  ? 101.228 96.659  133.744 1.00 107.52 ?  52   THR R CG2 1 
ATOM 2948 N N   . LEU B 1 77  ? 101.530 100.228 131.911 1.00 107.31 ?  53   LEU R N   1 
ATOM 2949 C CA  . LEU B 1 77  ? 101.028 100.723 130.634 1.00 107.31 ?  53   LEU R CA  1 
ATOM 2950 C C   . LEU B 1 77  ? 102.169 100.966 129.655 1.00 107.31 ?  53   LEU R C   1 
ATOM 2951 O O   . LEU B 1 77  ? 102.050 100.652 128.465 1.00 107.31 ?  53   LEU R O   1 
ATOM 2952 C CB  . LEU B 1 77  ? 100.217 102.001 130.844 1.00 107.31 ?  53   LEU R CB  1 
ATOM 2953 C CG  . LEU B 1 77  ? 98.703  101.859 131.033 1.00 107.31 ?  53   LEU R CG  1 
ATOM 2954 C CD1 . LEU B 1 77  ? 98.024  101.585 129.700 1.00 107.31 ?  53   LEU R CD1 1 
ATOM 2955 C CD2 . LEU B 1 77  ? 98.357  100.778 132.047 1.00 107.31 ?  53   LEU R CD2 1 
ATOM 2956 N N   . VAL B 1 78  ? 103.282 101.522 130.138 1.00 103.72 ?  54   VAL R N   1 
ATOM 2957 C CA  . VAL B 1 78  ? 104.423 101.789 129.264 1.00 103.72 ?  54   VAL R CA  1 
ATOM 2958 C C   . VAL B 1 78  ? 104.950 100.490 128.669 1.00 103.72 ?  54   VAL R C   1 
ATOM 2959 O O   . VAL B 1 78  ? 105.178 100.383 127.455 1.00 103.72 ?  54   VAL R O   1 
ATOM 2960 C CB  . VAL B 1 78  ? 105.522 102.540 130.037 1.00 103.72 ?  54   VAL R CB  1 
ATOM 2961 C CG1 . VAL B 1 78  ? 106.894 102.242 129.448 1.00 103.72 ?  54   VAL R CG1 1 
ATOM 2962 C CG2 . VAL B 1 78  ? 105.248 104.033 130.039 1.00 103.72 ?  54   VAL R CG2 1 
ATOM 2963 N N   . SER B 1 79  ? 105.142 99.478  129.518 1.00 104.32 ?  55   SER R N   1 
ATOM 2964 C CA  . SER B 1 79  ? 105.659 98.202  129.038 1.00 104.32 ?  55   SER R CA  1 
ATOM 2965 C C   . SER B 1 79  ? 104.702 97.560  128.047 1.00 104.32 ?  55   SER R C   1 
ATOM 2966 O O   . SER B 1 79  ? 105.127 97.051  127.001 1.00 104.32 ?  55   SER R O   1 
ATOM 2967 C CB  . SER B 1 79  ? 105.917 97.262  130.215 1.00 104.32 ?  55   SER R CB  1 
ATOM 2968 O OG  . SER B 1 79  ? 106.970 97.741  131.031 1.00 104.32 ?  55   SER R OG  1 
ATOM 2969 N N   . CYS B 1 80  ? 103.403 97.574  128.356 1.00 111.15 ?  56   CYS R N   1 
ATOM 2970 C CA  . CYS B 1 80  ? 102.429 96.961  127.461 1.00 111.15 ?  56   CYS R CA  1 
ATOM 2971 C C   . CYS B 1 80  ? 102.405 97.665  126.112 1.00 111.15 ?  56   CYS R C   1 
ATOM 2972 O O   . CYS B 1 80  ? 102.351 97.011  125.063 1.00 111.15 ?  56   CYS R O   1 
ATOM 2973 C CB  . CYS B 1 80  ? 101.042 96.978  128.102 1.00 111.15 ?  56   CYS R CB  1 
ATOM 2974 S SG  . CYS B 1 80  ? 100.845 95.835  129.489 1.00 111.15 ?  56   CYS R SG  1 
ATOM 2975 N N   . GLU B 1 81  ? 102.448 98.998  126.116 1.00 108.16 ?  57   GLU R N   1 
ATOM 2976 C CA  . GLU B 1 81  ? 102.419 99.734  124.860 1.00 108.16 ?  57   GLU R CA  1 
ATOM 2977 C C   . GLU B 1 81  ? 103.668 99.462  124.034 1.00 108.16 ?  57   GLU R C   1 
ATOM 2978 O O   . GLU B 1 81  ? 103.582 99.270  122.815 1.00 108.16 ?  57   GLU R O   1 
ATOM 2979 C CB  . GLU B 1 81  ? 102.260 101.230 125.132 1.00 108.16 ?  57   GLU R CB  1 
ATOM 2980 C CG  . GLU B 1 81  ? 103.085 102.132 124.227 1.00 108.16 ?  57   GLU R CG  1 
ATOM 2981 C CD  . GLU B 1 81  ? 102.414 102.382 122.889 1.00 108.16 ?  57   GLU R CD  1 
ATOM 2982 O OE1 . GLU B 1 81  ? 101.261 101.937 122.708 1.00 108.16 ?  57   GLU R OE1 1 
ATOM 2983 O OE2 . GLU B 1 81  ? 103.038 103.023 122.019 1.00 108.16 -1 57   GLU R OE2 1 
ATOM 2984 N N   . ASN B 1 82  ? 104.837 99.428  124.674 1.00 102.79 ?  58   ASN R N   1 
ATOM 2985 C CA  . ASN B 1 82  ? 106.069 99.261  123.916 1.00 102.79 ?  58   ASN R CA  1 
ATOM 2986 C C   . ASN B 1 82  ? 106.310 97.829  123.456 1.00 102.79 ?  58   ASN R C   1 
ATOM 2987 O O   . ASN B 1 82  ? 107.041 97.622  122.477 1.00 102.79 ?  58   ASN R O   1 
ATOM 2988 C CB  . ASN B 1 82  ? 107.261 99.738  124.737 1.00 102.79 ?  58   ASN R CB  1 
ATOM 2989 C CG  . ASN B 1 82  ? 108.081 100.770 124.009 1.00 102.79 ?  58   ASN R CG  1 
ATOM 2990 O OD1 . ASN B 1 82  ? 107.545 101.715 123.435 1.00 102.79 ?  58   ASN R OD1 1 
ATOM 2991 N ND2 . ASN B 1 82  ? 109.388 100.581 124.003 1.00 102.79 ?  58   ASN R ND2 1 
ATOM 2992 N N   . ALA B 1 83  ? 105.738 96.839  124.142 1.00 107.20 ?  59   ALA R N   1 
ATOM 2993 C CA  . ALA B 1 83  ? 105.989 95.454  123.761 1.00 107.20 ?  59   ALA R CA  1 
ATOM 2994 C C   . ALA B 1 83  ? 105.508 95.179  122.342 1.00 107.20 ?  59   ALA R C   1 
ATOM 2995 O O   . ALA B 1 83  ? 106.222 94.570  121.537 1.00 107.20 ?  59   ALA R O   1 
ATOM 2996 C CB  . ALA B 1 83  ? 105.316 94.506  124.754 1.00 107.20 ?  59   ALA R CB  1 
ATOM 2997 N N   . LEU B 1 84  ? 104.299 95.637  122.014 1.00 107.66 ?  60   LEU R N   1 
ATOM 2998 C CA  . LEU B 1 84  ? 103.749 95.360  120.692 1.00 107.66 ?  60   LEU R CA  1 
ATOM 2999 C C   . LEU B 1 84  ? 104.589 96.005  119.599 1.00 107.66 ?  60   LEU R C   1 
ATOM 3000 O O   . LEU B 1 84  ? 104.881 95.371  118.578 1.00 107.66 ?  60   LEU R O   1 
ATOM 3001 C CB  . LEU B 1 84  ? 102.292 95.823  120.620 1.00 107.66 ?  60   LEU R CB  1 
ATOM 3002 C CG  . LEU B 1 84  ? 101.944 97.314  120.651 1.00 107.66 ?  60   LEU R CG  1 
ATOM 3003 C CD1 . LEU B 1 84  ? 101.733 97.860  119.245 1.00 107.66 ?  60   LEU R CD1 1 
ATOM 3004 C CD2 . LEU B 1 84  ? 100.716 97.559  121.515 1.00 107.66 ?  60   LEU R CD2 1 
ATOM 3005 N N   . VAL B 1 85  ? 105.014 97.254  119.803 1.00 106.96 ?  61   VAL R N   1 
ATOM 3006 C CA  . VAL B 1 85  ? 105.750 97.943  118.751 1.00 106.96 ?  61   VAL R CA  1 
ATOM 3007 C C   . VAL B 1 85  ? 107.133 97.331  118.578 1.00 106.96 ?  61   VAL R C   1 
ATOM 3008 O O   . VAL B 1 85  ? 107.605 97.154  117.449 1.00 106.96 ?  61   VAL R O   1 
ATOM 3009 C CB  . VAL B 1 85  ? 105.817 99.459  119.021 1.00 106.96 ?  61   VAL R CB  1 
ATOM 3010 C CG1 . VAL B 1 85  ? 106.398 99.753  120.382 1.00 106.96 ?  61   VAL R CG1 1 
ATOM 3011 C CG2 . VAL B 1 85  ? 106.620 100.159 117.932 1.00 106.96 ?  61   VAL R CG2 1 
ATOM 3012 N N   . VAL B 1 86  ? 107.797 96.965  119.678 1.00 105.19 ?  62   VAL R N   1 
ATOM 3013 C CA  . VAL B 1 86  ? 109.113 96.353  119.532 1.00 105.19 ?  62   VAL R CA  1 
ATOM 3014 C C   . VAL B 1 86  ? 108.992 94.986  118.867 1.00 105.19 ?  62   VAL R C   1 
ATOM 3015 O O   . VAL B 1 86  ? 109.828 94.612  118.032 1.00 105.19 ?  62   VAL R O   1 
ATOM 3016 C CB  . VAL B 1 86  ? 109.843 96.286  120.888 1.00 105.19 ?  62   VAL R CB  1 
ATOM 3017 C CG1 . VAL B 1 86  ? 109.241 95.234  121.804 1.00 105.19 ?  62   VAL R CG1 1 
ATOM 3018 C CG2 . VAL B 1 86  ? 111.329 96.025  120.676 1.00 105.19 ?  62   VAL R CG2 1 
ATOM 3019 N N   . ALA B 1 87  ? 107.934 94.235  119.187 1.00 106.23 ?  63   ALA R N   1 
ATOM 3020 C CA  . ALA B 1 87  ? 107.746 92.931  118.565 1.00 106.23 ?  63   ALA R CA  1 
ATOM 3021 C C   . ALA B 1 87  ? 107.506 93.069  117.068 1.00 106.23 ?  63   ALA R C   1 
ATOM 3022 O O   . ALA B 1 87  ? 108.105 92.347  116.263 1.00 106.23 ?  63   ALA R O   1 
ATOM 3023 C CB  . ALA B 1 87  ? 106.587 92.193  119.234 1.00 106.23 ?  63   ALA R CB  1 
ATOM 3024 N N   . ILE B 1 88  ? 106.638 94.001  116.674 1.00 107.91 ?  64   ILE R N   1 
ATOM 3025 C CA  . ILE B 1 88  ? 106.365 94.189  115.252 1.00 107.91 ?  64   ILE R CA  1 
ATOM 3026 C C   . ILE B 1 88  ? 107.619 94.649  114.524 1.00 107.91 ?  64   ILE R C   1 
ATOM 3027 O O   . ILE B 1 88  ? 107.913 94.186  113.416 1.00 107.91 ?  64   ILE R O   1 
ATOM 3028 C CB  . ILE B 1 88  ? 105.195 95.168  115.050 1.00 107.91 ?  64   ILE R CB  1 
ATOM 3029 C CG1 . ILE B 1 88  ? 103.941 94.646  115.750 1.00 107.91 ?  64   ILE R CG1 1 
ATOM 3030 C CG2 . ILE B 1 88  ? 104.929 95.384  113.569 1.00 107.91 ?  64   ILE R CG2 1 
ATOM 3031 C CD1 . ILE B 1 88  ? 102.753 95.571  115.644 1.00 107.91 ?  64   ILE R CD1 1 
ATOM 3032 N N   . ILE B 1 89  ? 108.383 95.560  115.133 1.00 111.37 ?  65   ILE R N   1 
ATOM 3033 C CA  . ILE B 1 89  ? 109.592 96.060  114.484 1.00 111.37 ?  65   ILE R CA  1 
ATOM 3034 C C   . ILE B 1 89  ? 110.591 94.931  114.271 1.00 111.37 ?  65   ILE R C   1 
ATOM 3035 O O   . ILE B 1 89  ? 111.177 94.798  113.190 1.00 111.37 ?  65   ILE R O   1 
ATOM 3036 C CB  . ILE B 1 89  ? 110.203 97.212  115.304 1.00 111.37 ?  65   ILE R CB  1 
ATOM 3037 C CG1 . ILE B 1 89  ? 109.388 98.492  115.113 1.00 111.37 ?  65   ILE R CG1 1 
ATOM 3038 C CG2 . ILE B 1 89  ? 111.653 97.443  114.905 1.00 111.37 ?  65   ILE R CG2 1 
ATOM 3039 C CD1 . ILE B 1 89  ? 109.406 99.024  113.697 1.00 111.37 ?  65   ILE R CD1 1 
ATOM 3040 N N   . VAL B 1 90  ? 110.797 94.093  115.290 1.00 110.39 ?  66   VAL R N   1 
ATOM 3041 C CA  . VAL B 1 90  ? 111.756 93.007  115.139 1.00 110.39 ?  66   VAL R CA  1 
ATOM 3042 C C   . VAL B 1 90  ? 111.217 91.899  114.243 1.00 110.39 ?  66   VAL R C   1 
ATOM 3043 O O   . VAL B 1 90  ? 111.999 91.109  113.703 1.00 110.39 ?  66   VAL R O   1 
ATOM 3044 C CB  . VAL B 1 90  ? 112.159 92.449  116.517 1.00 110.39 ?  66   VAL R CB  1 
ATOM 3045 C CG1 . VAL B 1 90  ? 111.090 91.511  117.054 1.00 110.39 ?  66   VAL R CG1 1 
ATOM 3046 C CG2 . VAL B 1 90  ? 113.509 91.749  116.439 1.00 110.39 ?  66   VAL R CG2 1 
ATOM 3047 N N   . GLY B 1 91  ? 109.901 91.829  114.054 1.00 115.23 ?  67   GLY R N   1 
ATOM 3048 C CA  . GLY B 1 91  ? 109.297 90.710  113.358 1.00 115.23 ?  67   GLY R CA  1 
ATOM 3049 C C   . GLY B 1 91  ? 109.457 90.680  111.851 1.00 115.23 ?  67   GLY R C   1 
ATOM 3050 O O   . GLY B 1 91  ? 110.120 89.788  111.315 1.00 115.23 ?  67   GLY R O   1 
ATOM 3051 N N   . THR B 1 92  ? 108.860 91.643  111.160 1.00 117.06 ?  68   THR R N   1 
ATOM 3052 C CA  . THR B 1 92  ? 108.782 91.589  109.702 1.00 117.06 ?  68   THR R CA  1 
ATOM 3053 C C   . THR B 1 92  ? 110.167 91.723  109.084 1.00 117.06 ?  68   THR R C   1 
ATOM 3054 O O   . THR B 1 92  ? 110.856 92.718  109.339 1.00 117.06 ?  68   THR R O   1 
ATOM 3055 C CB  . THR B 1 92  ? 107.865 92.692  109.179 1.00 117.06 ?  68   THR R CB  1 
ATOM 3056 O OG1 . THR B 1 92  ? 106.531 92.472  109.655 1.00 117.06 ?  68   THR R OG1 1 
ATOM 3057 C CG2 . THR B 1 92  ? 107.857 92.699  107.658 1.00 117.06 ?  68   THR R CG2 1 
ATOM 3058 N N   . PRO B 1 93  ? 110.607 90.766  108.262 1.00 110.73 ?  69   PRO R N   1 
ATOM 3059 C CA  . PRO B 1 93  ? 111.959 90.857  107.685 1.00 110.73 ?  69   PRO R CA  1 
ATOM 3060 C C   . PRO B 1 93  ? 112.138 92.015  106.723 1.00 110.73 ?  69   PRO R C   1 
ATOM 3061 O O   . PRO B 1 93  ? 113.282 92.373  106.424 1.00 110.73 ?  69   PRO R O   1 
ATOM 3062 C CB  . PRO B 1 93  ? 112.145 89.514  106.964 1.00 110.73 ?  69   PRO R CB  1 
ATOM 3063 C CG  . PRO B 1 93  ? 110.878 88.760  107.102 1.00 110.73 ?  69   PRO R CG  1 
ATOM 3064 C CD  . PRO B 1 93  ? 109.880 89.547  107.873 1.00 110.73 ?  69   PRO R CD  1 
ATOM 3065 N N   . ALA B 1 94  ? 111.054 92.602  106.217 1.00 116.05 ?  70   ALA R N   1 
ATOM 3066 C CA  . ALA B 1 94  ? 111.176 93.704  105.273 1.00 116.05 ?  70   ALA R CA  1 
ATOM 3067 C C   . ALA B 1 94  ? 111.543 95.020  105.943 1.00 116.05 ?  70   ALA R C   1 
ATOM 3068 O O   . ALA B 1 94  ? 111.999 95.942  105.258 1.00 116.05 ?  70   ALA R O   1 
ATOM 3069 C CB  . ALA B 1 94  ? 109.873 93.874  104.490 1.00 116.05 ?  70   ALA R CB  1 
ATOM 3070 N N   . PHE B 1 95  ? 111.359 95.131  107.253 1.00 116.14 ?  71   PHE R N   1 
ATOM 3071 C CA  . PHE B 1 95  ? 111.590 96.387  107.968 1.00 116.14 ?  71   PHE R CA  1 
ATOM 3072 C C   . PHE B 1 95  ? 112.984 96.438  108.582 1.00 116.14 ?  71   PHE R C   1 
ATOM 3073 O O   . PHE B 1 95  ? 113.138 96.657  109.783 1.00 116.14 ?  71   PHE R O   1 
ATOM 3074 C CB  . PHE B 1 95  ? 110.523 96.582  109.037 1.00 116.14 ?  71   PHE R CB  1 
ATOM 3075 C CG  . PHE B 1 95  ? 109.185 96.990  108.493 1.00 116.14 ?  71   PHE R CG  1 
ATOM 3076 C CD1 . PHE B 1 95  ? 109.043 97.374  107.171 1.00 116.14 ?  71   PHE R CD1 1 
ATOM 3077 C CD2 . PHE B 1 95  ? 108.066 96.994  109.310 1.00 116.14 ?  71   PHE R CD2 1 
ATOM 3078 C CE1 . PHE B 1 95  ? 107.809 97.751  106.672 1.00 116.14 ?  71   PHE R CE1 1 
ATOM 3079 C CE2 . PHE B 1 95  ? 106.830 97.369  108.819 1.00 116.14 ?  71   PHE R CE2 1 
ATOM 3080 C CZ  . PHE B 1 95  ? 106.702 97.748  107.498 1.00 116.14 ?  71   PHE R CZ  1 
ATOM 3081 N N   . ARG B 1 96  ? 114.022 96.238  107.771 1.00 108.21 ?  72   ARG R N   1 
ATOM 3082 C CA  . ARG B 1 96  ? 115.407 96.346  108.219 1.00 108.21 ?  72   ARG R CA  1 
ATOM 3083 C C   . ARG B 1 96  ? 116.106 97.562  107.618 1.00 108.21 ?  72   ARG R C   1 
ATOM 3084 O O   . ARG B 1 96  ? 117.299 97.511  107.312 1.00 108.21 ?  72   ARG R O   1 
ATOM 3085 C CB  . ARG B 1 96  ? 116.205 95.077  107.901 1.00 108.21 ?  72   ARG R CB  1 
ATOM 3086 C CG  . ARG B 1 96  ? 115.579 93.714  108.242 1.00 108.21 ?  72   ARG R CG  1 
ATOM 3087 C CD  . ARG B 1 96  ? 114.630 93.739  109.434 1.00 108.21 ?  72   ARG R CD  1 
ATOM 3088 N NE  . ARG B 1 96  ? 114.078 92.421  109.722 1.00 108.21 ?  72   ARG R NE  1 
ATOM 3089 C CZ  . ARG B 1 96  ? 113.372 92.122  110.804 1.00 108.21 ?  72   ARG R CZ  1 
ATOM 3090 N NH1 . ARG B 1 96  ? 113.121 93.026  111.737 1.00 108.21 1  72   ARG R NH1 1 
ATOM 3091 N NH2 . ARG B 1 96  ? 112.903 90.888  110.952 1.00 108.21 ?  72   ARG R NH2 1 
ATOM 3092 N N   . ALA B 1 97  ? 115.377 98.659  107.443 1.00 104.01 ?  73   ALA R N   1 
ATOM 3093 C CA  . ALA B 1 97  ? 115.980 99.871  106.917 1.00 104.01 ?  73   ALA R CA  1 
ATOM 3094 C C   . ALA B 1 97  ? 116.969 100.451 107.928 1.00 104.01 ?  73   ALA R C   1 
ATOM 3095 O O   . ALA B 1 97  ? 116.878 100.167 109.126 1.00 104.01 ?  73   ALA R O   1 
ATOM 3096 C CB  . ALA B 1 97  ? 114.902 100.899 106.586 1.00 104.01 ?  73   ALA R CB  1 
ATOM 3097 N N   . PRO B 1 98  ? 117.939 101.250 107.469 1.00 96.69  ?  74   PRO R N   1 
ATOM 3098 C CA  . PRO B 1 98  ? 118.883 101.859 108.422 1.00 96.69  ?  74   PRO R CA  1 
ATOM 3099 C C   . PRO B 1 98  ? 118.214 102.705 109.490 1.00 96.69  ?  74   PRO R C   1 
ATOM 3100 O O   . PRO B 1 98  ? 118.673 102.715 110.639 1.00 96.69  ?  74   PRO R O   1 
ATOM 3101 C CB  . PRO B 1 98  ? 119.792 102.701 107.519 1.00 96.69  ?  74   PRO R CB  1 
ATOM 3102 C CG  . PRO B 1 98  ? 119.714 102.040 106.195 1.00 96.69  ?  74   PRO R CG  1 
ATOM 3103 C CD  . PRO B 1 98  ? 118.308 101.536 106.074 1.00 96.69  ?  74   PRO R CD  1 
ATOM 3104 N N   . MET B 1 99  ? 117.141 103.417 109.150 1.00 100.54 ?  75   MET R N   1 
ATOM 3105 C CA  . MET B 1 99  ? 116.462 104.247 110.134 1.00 100.54 ?  75   MET R CA  1 
ATOM 3106 C C   . MET B 1 99  ? 115.489 103.460 110.999 1.00 100.54 ?  75   MET R C   1 
ATOM 3107 O O   . MET B 1 99  ? 115.017 103.991 112.009 1.00 100.54 ?  75   MET R O   1 
ATOM 3108 C CB  . MET B 1 99  ? 115.783 105.431 109.420 1.00 100.54 ?  75   MET R CB  1 
ATOM 3109 C CG  . MET B 1 99  ? 114.425 105.225 108.720 1.00 100.54 ?  75   MET R CG  1 
ATOM 3110 S SD  . MET B 1 99  ? 112.989 104.608 109.619 1.00 100.54 ?  75   MET R SD  1 
ATOM 3111 C CE  . MET B 1 99  ? 112.716 105.944 110.781 1.00 100.54 ?  75   MET R CE  1 
ATOM 3112 N N   . PHE B 1 100 ? 115.187 102.212 110.638 1.00 102.52 ?  76   PHE R N   1 
ATOM 3113 C CA  . PHE B 1 100 ? 114.364 101.372 111.501 1.00 102.52 ?  76   PHE R CA  1 
ATOM 3114 C C   . PHE B 1 100 ? 115.137 100.894 112.723 1.00 102.52 ?  76   PHE R C   1 
ATOM 3115 O O   . PHE B 1 100 ? 114.538 100.640 113.776 1.00 102.52 ?  76   PHE R O   1 
ATOM 3116 C CB  . PHE B 1 100 ? 113.831 100.178 110.711 1.00 102.52 ?  76   PHE R CB  1 
ATOM 3117 C CG  . PHE B 1 100 ? 112.613 100.488 109.894 1.00 102.52 ?  76   PHE R CG  1 
ATOM 3118 C CD1 . PHE B 1 100 ? 111.805 101.563 110.212 1.00 102.52 ?  76   PHE R CD1 1 
ATOM 3119 C CD2 . PHE B 1 100 ? 112.286 99.714  108.796 1.00 102.52 ?  76   PHE R CD2 1 
ATOM 3120 C CE1 . PHE B 1 100 ? 110.685 101.853 109.459 1.00 102.52 ?  76   PHE R CE1 1 
ATOM 3121 C CE2 . PHE B 1 100 ? 111.167 99.998  108.037 1.00 102.52 ?  76   PHE R CE2 1 
ATOM 3122 C CZ  . PHE B 1 100 ? 110.366 101.070 108.369 1.00 102.52 ?  76   PHE R CZ  1 
ATOM 3123 N N   . LEU B 1 101 ? 116.459 100.763 112.601 1.00 94.87  ?  77   LEU R N   1 
ATOM 3124 C CA  . LEU B 1 101 ? 117.262 100.287 113.722 1.00 94.87  ?  77   LEU R CA  1 
ATOM 3125 C C   . LEU B 1 101 ? 117.200 101.255 114.896 1.00 94.87  ?  77   LEU R C   1 
ATOM 3126 O O   . LEU B 1 101 ? 117.143 100.834 116.057 1.00 94.87  ?  77   LEU R O   1 
ATOM 3127 C CB  . LEU B 1 101 ? 118.707 100.075 113.276 1.00 94.87  ?  77   LEU R CB  1 
ATOM 3128 C CG  . LEU B 1 101 ? 118.982 98.822  112.442 1.00 94.87  ?  77   LEU R CG  1 
ATOM 3129 C CD1 . LEU B 1 101 ? 120.475 98.540  112.372 1.00 94.87  ?  77   LEU R CD1 1 
ATOM 3130 C CD2 . LEU B 1 101 ? 118.233 97.623  113.005 1.00 94.87  ?  77   LEU R CD2 1 
ATOM 3131 N N   . LEU B 1 102 ? 117.217 102.559 114.616 1.00 85.19  ?  78   LEU R N   1 
ATOM 3132 C CA  . LEU B 1 102 ? 117.155 103.543 115.690 1.00 85.19  ?  78   LEU R CA  1 
ATOM 3133 C C   . LEU B 1 102 ? 115.807 103.500 116.400 1.00 85.19  ?  78   LEU R C   1 
ATOM 3134 O O   . LEU B 1 102 ? 115.741 103.615 117.632 1.00 85.19  ?  78   LEU R O   1 
ATOM 3135 C CB  . LEU B 1 102 ? 117.435 104.939 115.135 1.00 85.19  ?  78   LEU R CB  1 
ATOM 3136 C CG  . LEU B 1 102 ? 118.901 105.352 114.979 1.00 85.19  ?  78   LEU R CG  1 
ATOM 3137 C CD1 . LEU B 1 102 ? 119.606 104.512 113.932 1.00 85.19  ?  78   LEU R CD1 1 
ATOM 3138 C CD2 . LEU B 1 102 ? 119.004 106.817 114.623 1.00 85.19  ?  78   LEU R CD2 1 
ATOM 3139 N N   . VAL B 1 103 ? 114.723 103.340 115.640 1.00 83.41  ?  79   VAL R N   1 
ATOM 3140 C CA  . VAL B 1 103 ? 113.405 103.211 116.251 1.00 83.41  ?  79   VAL R CA  1 
ATOM 3141 C C   . VAL B 1 103 ? 113.352 101.968 117.123 1.00 83.41  ?  79   VAL R C   1 
ATOM 3142 O O   . VAL B 1 103 ? 112.791 101.986 118.227 1.00 83.41  ?  79   VAL R O   1 
ATOM 3143 C CB  . VAL B 1 103 ? 112.311 103.192 115.169 1.00 83.41  ?  79   VAL R CB  1 
ATOM 3144 C CG1 . VAL B 1 103 ? 110.937 103.107 115.810 1.00 83.41  ?  79   VAL R CG1 1 
ATOM 3145 C CG2 . VAL B 1 103 ? 112.418 104.425 114.292 1.00 83.41  ?  79   VAL R CG2 1 
ATOM 3146 N N   . GLY B 1 104 ? 113.935 100.869 116.646 1.00 87.31  ?  80   GLY R N   1 
ATOM 3147 C CA  . GLY B 1 104 ? 114.004 99.673  117.466 1.00 87.31  ?  80   GLY R CA  1 
ATOM 3148 C C   . GLY B 1 104 ? 114.785 99.892  118.747 1.00 87.31  ?  80   GLY R C   1 
ATOM 3149 O O   . GLY B 1 104 ? 114.405 99.397  119.811 1.00 87.31  ?  80   GLY R O   1 
ATOM 3150 N N   . SER B 1 105 ? 115.894 100.631 118.660 1.00 86.49  ?  81   SER R N   1 
ATOM 3151 C CA  . SER B 1 105 ? 116.692 100.913 119.849 1.00 86.49  ?  81   SER R CA  1 
ATOM 3152 C C   . SER B 1 105 ? 115.896 101.718 120.864 1.00 86.49  ?  81   SER R C   1 
ATOM 3153 O O   . SER B 1 105 ? 115.909 101.415 122.065 1.00 86.49  ?  81   SER R O   1 
ATOM 3154 C CB  . SER B 1 105 ? 117.961 101.667 119.463 1.00 86.49  ?  81   SER R CB  1 
ATOM 3155 O OG  . SER B 1 105 ? 117.766 103.062 119.594 1.00 86.49  ?  81   SER R OG  1 
ATOM 3156 N N   . LEU B 1 106 ? 115.192 102.747 120.396 1.00 82.46  ?  82   LEU R N   1 
ATOM 3157 C CA  . LEU B 1 106 ? 114.362 103.542 121.293 1.00 82.46  ?  82   LEU R CA  1 
ATOM 3158 C C   . LEU B 1 106 ? 113.274 102.688 121.932 1.00 82.46  ?  82   LEU R C   1 
ATOM 3159 O O   . LEU B 1 106 ? 113.003 102.805 123.136 1.00 82.46  ?  82   LEU R O   1 
ATOM 3160 C CB  . LEU B 1 106 ? 113.755 104.712 120.523 1.00 82.46  ?  82   LEU R CB  1 
ATOM 3161 C CG  . LEU B 1 106 ? 112.701 105.587 121.191 1.00 82.46  ?  82   LEU R CG  1 
ATOM 3162 C CD1 . LEU B 1 106 ? 112.943 107.033 120.803 1.00 82.46  ?  82   LEU R CD1 1 
ATOM 3163 C CD2 . LEU B 1 106 ? 111.309 105.149 120.781 1.00 82.46  ?  82   LEU R CD2 1 
ATOM 3164 N N   . ALA B 1 107 ? 112.643 101.819 121.140 1.00 88.34  ?  83   ALA R N   1 
ATOM 3165 C CA  . ALA B 1 107 ? 111.592 100.965 121.677 1.00 88.34  ?  83   ALA R CA  1 
ATOM 3166 C C   . ALA B 1 107 ? 112.133 100.024 122.744 1.00 88.34  ?  83   ALA R C   1 
ATOM 3167 O O   . ALA B 1 107 ? 111.508 99.840  123.797 1.00 88.34  ?  83   ALA R O   1 
ATOM 3168 C CB  . ALA B 1 107 ? 110.932 100.175 120.548 1.00 88.34  ?  83   ALA R CB  1 
ATOM 3169 N N   . VAL B 1 108 ? 113.294 99.417  122.494 1.00 87.16  ?  84   VAL R N   1 
ATOM 3170 C CA  . VAL B 1 108 ? 113.850 98.487  123.470 1.00 87.16  ?  84   VAL R CA  1 
ATOM 3171 C C   . VAL B 1 108 ? 114.262 99.228  124.735 1.00 87.16  ?  84   VAL R C   1 
ATOM 3172 O O   . VAL B 1 108 ? 114.112 98.709  125.848 1.00 87.16  ?  84   VAL R O   1 
ATOM 3173 C CB  . VAL B 1 108 ? 115.011 97.678  122.855 1.00 87.16  ?  84   VAL R CB  1 
ATOM 3174 C CG1 . VAL B 1 108 ? 116.340 98.411  122.965 1.00 87.16  ?  84   VAL R CG1 1 
ATOM 3175 C CG2 . VAL B 1 108 ? 115.102 96.307  123.508 1.00 87.16  ?  84   VAL R CG2 1 
ATOM 3176 N N   . ALA B 1 109 ? 114.755 100.462 124.595 1.00 88.72  ?  85   ALA R N   1 
ATOM 3177 C CA  . ALA B 1 109 ? 115.099 101.247 125.775 1.00 88.72  ?  85   ALA R CA  1 
ATOM 3178 C C   . ALA B 1 109 ? 113.865 101.546 126.617 1.00 88.72  ?  85   ALA R C   1 
ATOM 3179 O O   . ALA B 1 109 ? 113.896 101.426 127.849 1.00 88.72  ?  85   ALA R O   1 
ATOM 3180 C CB  . ALA B 1 109 ? 115.795 102.542 125.360 1.00 88.72  ?  85   ALA R CB  1 
ATOM 3181 N N   . ASP B 1 110 ? 112.763 101.929 125.970 1.00 99.33  ?  86   ASP R N   1 
ATOM 3182 C CA  . ASP B 1 110 ? 111.551 102.227 126.728 1.00 99.33  ?  86   ASP R CA  1 
ATOM 3183 C C   . ASP B 1 110 ? 110.991 100.973 127.393 1.00 99.33  ?  86   ASP R C   1 
ATOM 3184 O O   . ASP B 1 110 ? 110.509 101.027 128.535 1.00 99.33  ?  86   ASP R O   1 
ATOM 3185 C CB  . ASP B 1 110 ? 110.509 102.877 125.820 1.00 99.33  ?  86   ASP R CB  1 
ATOM 3186 C CG  . ASP B 1 110 ? 109.271 103.313 126.576 1.00 99.33  ?  86   ASP R CG  1 
ATOM 3187 O OD1 . ASP B 1 110 ? 109.388 103.621 127.780 1.00 99.33  ?  86   ASP R OD1 1 
ATOM 3188 O OD2 . ASP B 1 110 ? 108.180 103.344 125.967 1.00 99.33  -1 86   ASP R OD2 1 
ATOM 3189 N N   . LEU B 1 111 ? 111.041 99.834  126.696 1.00 100.06 ?  87   LEU R N   1 
ATOM 3190 C CA  . LEU B 1 111 ? 110.585 98.585  127.299 1.00 100.06 ?  87   LEU R CA  1 
ATOM 3191 C C   . LEU B 1 111 ? 111.432 98.221  128.511 1.00 100.06 ?  87   LEU R C   1 
ATOM 3192 O O   . LEU B 1 111 ? 110.907 97.770  129.539 1.00 100.06 ?  87   LEU R O   1 
ATOM 3193 C CB  . LEU B 1 111 ? 110.617 97.459  126.266 1.00 100.06 ?  87   LEU R CB  1 
ATOM 3194 C CG  . LEU B 1 111 ? 110.193 96.074  126.760 1.00 100.06 ?  87   LEU R CG  1 
ATOM 3195 C CD1 . LEU B 1 111 ? 108.754 96.091  127.251 1.00 100.06 ?  87   LEU R CD1 1 
ATOM 3196 C CD2 . LEU B 1 111 ? 110.378 95.034  125.666 1.00 100.06 ?  87   LEU R CD2 1 
ATOM 3197 N N   . LEU B 1 112 ? 112.747 98.415  128.406 1.00 91.60  ?  88   LEU R N   1 
ATOM 3198 C CA  . LEU B 1 112 ? 113.630 98.173  129.539 1.00 91.60  ?  88   LEU R CA  1 
ATOM 3199 C C   . LEU B 1 112 ? 113.276 99.084  130.706 1.00 91.60  ?  88   LEU R C   1 
ATOM 3200 O O   . LEU B 1 112 ? 113.279 98.650  131.863 1.00 91.60  ?  88   LEU R O   1 
ATOM 3201 C CB  . LEU B 1 112 ? 115.082 98.368  129.097 1.00 91.60  ?  88   LEU R CB  1 
ATOM 3202 C CG  . LEU B 1 112 ? 116.260 97.861  129.930 1.00 91.60  ?  88   LEU R CG  1 
ATOM 3203 C CD1 . LEU B 1 112 ? 117.519 97.861  129.082 1.00 91.60  ?  88   LEU R CD1 1 
ATOM 3204 C CD2 . LEU B 1 112 ? 116.477 98.720  131.152 1.00 91.60  ?  88   LEU R CD2 1 
ATOM 3205 N N   . ALA B 1 113 ? 112.967 100.349 130.421 1.00 91.31  ?  89   ALA R N   1 
ATOM 3206 C CA  . ALA B 1 113 ? 112.583 101.274 131.484 1.00 91.31  ?  89   ALA R CA  1 
ATOM 3207 C C   . ALA B 1 113 ? 111.323 100.803 132.198 1.00 91.31  ?  89   ALA R C   1 
ATOM 3208 O O   . ALA B 1 113 ? 111.249 100.817 133.433 1.00 91.31  ?  89   ALA R O   1 
ATOM 3209 C CB  . ALA B 1 113 ? 112.379 102.676 130.911 1.00 91.31  ?  89   ALA R CB  1 
ATOM 3210 N N   . GLY B 1 114 ? 110.316 100.389 131.431 1.00 97.32  ?  90   GLY R N   1 
ATOM 3211 C CA  . GLY B 1 114 ? 109.085 99.921  132.050 1.00 97.32  ?  90   GLY R CA  1 
ATOM 3212 C C   . GLY B 1 114 ? 109.295 98.677  132.894 1.00 97.32  ?  90   GLY R C   1 
ATOM 3213 O O   . GLY B 1 114 ? 108.767 98.567  134.009 1.00 97.32  ?  90   GLY R O   1 
ATOM 3214 N N   . LEU B 1 115 ? 110.072 97.724  132.373 1.00 99.74  ?  91   LEU R N   1 
ATOM 3215 C CA  . LEU B 1 115 ? 110.377 96.525  133.142 1.00 99.74  ?  91   LEU R CA  1 
ATOM 3216 C C   . LEU B 1 115 ? 111.109 96.877  134.428 1.00 99.74  ?  91   LEU R C   1 
ATOM 3217 O O   . LEU B 1 115 ? 110.814 96.322  135.492 1.00 99.74  ?  91   LEU R O   1 
ATOM 3218 C CB  . LEU B 1 115 ? 111.203 95.555  132.297 1.00 99.74  ?  91   LEU R CB  1 
ATOM 3219 C CG  . LEU B 1 115 ? 111.537 94.202  132.927 1.00 99.74  ?  91   LEU R CG  1 
ATOM 3220 C CD1 . LEU B 1 115 ? 111.223 93.071  131.961 1.00 99.74  ?  91   LEU R CD1 1 
ATOM 3221 C CD2 . LEU B 1 115 ? 112.997 94.152  133.355 1.00 99.74  ?  91   LEU R CD2 1 
ATOM 3222 N N   . GLY B 1 116 ? 112.065 97.804  134.351 1.00 100.66 ?  92   GLY R N   1 
ATOM 3223 C CA  . GLY B 1 116 ? 112.778 98.211  135.547 1.00 100.66 ?  92   GLY R CA  1 
ATOM 3224 C C   . GLY B 1 116 ? 111.867 98.841  136.581 1.00 100.66 ?  92   GLY R C   1 
ATOM 3225 O O   . GLY B 1 116 ? 111.989 98.568  137.776 1.00 100.66 ?  92   GLY R O   1 
ATOM 3226 N N   . LEU B 1 117 ? 110.937 99.687  136.136 1.00 97.33  ?  93   LEU R N   1 
ATOM 3227 C CA  . LEU B 1 117 ? 110.036 100.342 137.079 1.00 97.33  ?  93   LEU R CA  1 
ATOM 3228 C C   . LEU B 1 117 ? 109.134 99.328  137.773 1.00 97.33  ?  93   LEU R C   1 
ATOM 3229 O O   . LEU B 1 117 ? 108.957 99.368  139.000 1.00 97.33  ?  93   LEU R O   1 
ATOM 3230 C CB  . LEU B 1 117 ? 109.203 101.402 136.361 1.00 97.33  ?  93   LEU R CB  1 
ATOM 3231 C CG  . LEU B 1 117 ? 108.488 102.430 137.242 1.00 97.33  ?  93   LEU R CG  1 
ATOM 3232 C CD1 . LEU B 1 117 ? 109.284 102.720 138.505 1.00 97.33  ?  93   LEU R CD1 1 
ATOM 3233 C CD2 . LEU B 1 117 ? 108.226 103.710 136.465 1.00 97.33  ?  93   LEU R CD2 1 
ATOM 3234 N N   . VAL B 1 118 ? 108.556 98.402  137.004 1.00 95.07  ?  94   VAL R N   1 
ATOM 3235 C CA  . VAL B 1 118 ? 107.658 97.432  137.625 1.00 95.07  ?  94   VAL R CA  1 
ATOM 3236 C C   . VAL B 1 118 ? 108.437 96.502  138.549 1.00 95.07  ?  94   VAL R C   1 
ATOM 3237 O O   . VAL B 1 118 ? 107.959 96.140  139.632 1.00 95.07  ?  94   VAL R O   1 
ATOM 3238 C CB  . VAL B 1 118 ? 106.855 96.661  136.560 1.00 95.07  ?  94   VAL R CB  1 
ATOM 3239 C CG1 . VAL B 1 118 ? 107.763 95.869  135.640 1.00 95.07  ?  94   VAL R CG1 1 
ATOM 3240 C CG2 . VAL B 1 118 ? 105.835 95.747  137.225 1.00 95.07  ?  94   VAL R CG2 1 
ATOM 3241 N N   . LEU B 1 119 ? 109.660 96.130  138.163 1.00 99.55  ?  95   LEU R N   1 
ATOM 3242 C CA  . LEU B 1 119 ? 110.473 95.280  139.025 1.00 99.55  ?  95   LEU R CA  1 
ATOM 3243 C C   . LEU B 1 119 ? 110.869 96.004  140.304 1.00 99.55  ?  95   LEU R C   1 
ATOM 3244 O O   . LEU B 1 119 ? 110.940 95.388  141.370 1.00 99.55  ?  95   LEU R O   1 
ATOM 3245 C CB  . LEU B 1 119 ? 111.713 94.802  138.273 1.00 99.55  ?  95   LEU R CB  1 
ATOM 3246 C CG  . LEU B 1 119 ? 111.679 93.372  137.729 1.00 99.55  ?  95   LEU R CG  1 
ATOM 3247 C CD1 . LEU B 1 119 ? 110.489 93.171  136.802 1.00 99.55  ?  95   LEU R CD1 1 
ATOM 3248 C CD2 . LEU B 1 119 ? 112.981 93.037  137.017 1.00 99.55  ?  95   LEU R CD2 1 
ATOM 3249 N N   . HIS B 1 120 ? 111.144 97.307  140.221 1.00 97.56  ?  96   HIS R N   1 
ATOM 3250 C CA  . HIS B 1 120 ? 111.471 98.064  141.424 1.00 97.56  ?  96   HIS R CA  1 
ATOM 3251 C C   . HIS B 1 120 ? 110.281 98.140  142.371 1.00 97.56  ?  96   HIS R C   1 
ATOM 3252 O O   . HIS B 1 120 ? 110.437 97.968  143.589 1.00 97.56  ?  96   HIS R O   1 
ATOM 3253 C CB  . HIS B 1 120 ? 111.948 99.465  141.053 1.00 97.56  ?  96   HIS R CB  1 
ATOM 3254 C CG  . HIS B 1 120 ? 112.333 100.300 142.233 1.00 97.56  ?  96   HIS R CG  1 
ATOM 3255 N ND1 . HIS B 1 120 ? 111.405 100.913 143.045 1.00 97.56  ?  96   HIS R ND1 1 
ATOM 3256 C CD2 . HIS B 1 120 ? 113.546 100.626 142.736 1.00 97.56  ?  96   HIS R CD2 1 
ATOM 3257 C CE1 . HIS B 1 120 ? 112.029 101.579 144.000 1.00 97.56  ?  96   HIS R CE1 1 
ATOM 3258 N NE2 . HIS B 1 120 ? 113.330 101.421 143.834 1.00 97.56  ?  96   HIS R NE2 1 
ATOM 3259 N N   . PHE B 1 121 ? 109.084 98.396  141.835 1.00 103.22 ?  97   PHE R N   1 
ATOM 3260 C CA  . PHE B 1 121 ? 107.902 98.370  142.693 1.00 103.22 ?  97   PHE R CA  1 
ATOM 3261 C C   . PHE B 1 121 ? 107.745 96.997  143.328 1.00 103.22 ?  97   PHE R C   1 
ATOM 3262 O O   . PHE B 1 121 ? 107.444 96.889  144.522 1.00 103.22 ?  97   PHE R O   1 
ATOM 3263 C CB  . PHE B 1 121 ? 106.655 98.775  141.897 1.00 103.22 ?  97   PHE R CB  1 
ATOM 3264 C CG  . PHE B 1 121 ? 105.370 98.834  142.714 1.00 103.22 ?  97   PHE R CG  1 
ATOM 3265 C CD1 . PHE B 1 121 ? 104.897 97.740  143.425 1.00 103.22 ?  97   PHE R CD1 1 
ATOM 3266 C CD2 . PHE B 1 121 ? 104.653 100.013 142.788 1.00 103.22 ?  97   PHE R CD2 1 
ATOM 3267 C CE1 . PHE B 1 121 ? 103.739 97.813  144.165 1.00 103.22 ?  97   PHE R CE1 1 
ATOM 3268 C CE2 . PHE B 1 121 ? 103.489 100.088 143.531 1.00 103.22 ?  97   PHE R CE2 1 
ATOM 3269 C CZ  . PHE B 1 121 ? 103.034 98.989  144.219 1.00 103.22 ?  97   PHE R CZ  1 
ATOM 3270 N N   . ALA B 1 122 ? 107.964 95.936  142.552 1.00 102.93 ?  98   ALA R N   1 
ATOM 3271 C CA  . ALA B 1 122 ? 107.901 94.597  143.125 1.00 102.93 ?  98   ALA R CA  1 
ATOM 3272 C C   . ALA B 1 122 ? 108.900 94.445  144.263 1.00 102.93 ?  98   ALA R C   1 
ATOM 3273 O O   . ALA B 1 122 ? 108.563 93.922  145.328 1.00 102.93 ?  98   ALA R O   1 
ATOM 3274 C CB  . ALA B 1 122 ? 108.152 93.549  142.042 1.00 102.93 ?  98   ALA R CB  1 
ATOM 3275 N N   . ALA B 1 123 ? 110.127 94.927  144.065 1.00 103.72 ?  99   ALA R N   1 
ATOM 3276 C CA  . ALA B 1 123 ? 111.157 94.789  145.087 1.00 103.72 ?  99   ALA R CA  1 
ATOM 3277 C C   . ALA B 1 123 ? 110.806 95.561  146.348 1.00 103.72 ?  99   ALA R C   1 
ATOM 3278 O O   . ALA B 1 123 ? 111.207 95.167  147.449 1.00 103.72 ?  99   ALA R O   1 
ATOM 3279 C CB  . ALA B 1 123 ? 112.507 95.252  144.540 1.00 103.72 ?  99   ALA R CB  1 
ATOM 3280 N N   . VAL B 1 124 ? 110.060 96.655  146.216 1.00 110.80 ?  100  VAL R N   1 
ATOM 3281 C CA  . VAL B 1 124 ? 109.659 97.431  147.385 1.00 110.80 ?  100  VAL R CA  1 
ATOM 3282 C C   . VAL B 1 124 ? 108.340 96.880  147.922 1.00 110.80 ?  100  VAL R C   1 
ATOM 3283 O O   . VAL B 1 124 ? 107.710 97.480  148.800 1.00 110.80 ?  100  VAL R O   1 
ATOM 3284 C CB  . VAL B 1 124 ? 109.567 98.934  147.051 1.00 110.80 ?  100  VAL R CB  1 
ATOM 3285 C CG1 . VAL B 1 124 ? 108.246 99.277  146.371 1.00 110.80 ?  100  VAL R CG1 1 
ATOM 3286 C CG2 . VAL B 1 124 ? 109.781 99.781  148.302 1.00 110.80 ?  100  VAL R CG2 1 
ATOM 3287 N N   . PHE B 1 125 ? 107.926 95.718  147.416 1.00 116.67 ?  101  PHE R N   1 
ATOM 3288 C CA  . PHE B 1 125 ? 106.691 95.067  147.847 1.00 116.67 ?  101  PHE R CA  1 
ATOM 3289 C C   . PHE B 1 125 ? 106.983 93.618  148.216 1.00 116.67 ?  101  PHE R C   1 
ATOM 3290 O O   . PHE B 1 125 ? 107.221 92.786  147.337 1.00 116.67 ?  101  PHE R O   1 
ATOM 3291 C CB  . PHE B 1 125 ? 105.621 95.139  146.759 1.00 116.67 ?  101  PHE R CB  1 
ATOM 3292 C CG  . PHE B 1 125 ? 104.300 94.556  147.172 1.00 116.67 ?  101  PHE R CG  1 
ATOM 3293 C CD1 . PHE B 1 125 ? 103.484 95.223  148.070 1.00 116.67 ?  101  PHE R CD1 1 
ATOM 3294 C CD2 . PHE B 1 125 ? 103.877 93.338  146.666 1.00 116.67 ?  101  PHE R CD2 1 
ATOM 3295 C CE1 . PHE B 1 125 ? 102.268 94.689  148.453 1.00 116.67 ?  101  PHE R CE1 1 
ATOM 3296 C CE2 . PHE B 1 125 ? 102.662 92.798  147.045 1.00 116.67 ?  101  PHE R CE2 1 
ATOM 3297 C CZ  . PHE B 1 125 ? 101.857 93.475  147.939 1.00 116.67 ?  101  PHE R CZ  1 
ATOM 3298 N N   . CYS B 1 126 ? 106.969 93.329  149.518 1.00 114.88 ?  102  CYS R N   1 
ATOM 3299 C CA  . CYS B 1 126 ? 107.045 91.968  150.064 1.00 114.88 ?  102  CYS R CA  1 
ATOM 3300 C C   . CYS B 1 126 ? 108.278 91.199  149.585 1.00 114.88 ?  102  CYS R C   1 
ATOM 3301 O O   . CYS B 1 126 ? 108.267 89.968  149.512 1.00 114.88 ?  102  CYS R O   1 
ATOM 3302 C CB  . CYS B 1 126 ? 105.761 91.177  149.773 1.00 114.88 ?  102  CYS R CB  1 
ATOM 3303 S SG  . CYS B 1 126 ? 105.557 90.486  148.109 1.00 114.88 ?  102  CYS R SG  1 
ATOM 3304 N N   . ILE B 1 127 ? 109.360 91.906  149.273 1.00 112.69 ?  103  ILE R N   1 
ATOM 3305 C CA  . ILE B 1 127 ? 110.680 91.303  149.109 1.00 112.69 ?  103  ILE R CA  1 
ATOM 3306 C C   . ILE B 1 127 ? 111.643 91.778  150.189 1.00 112.69 ?  103  ILE R C   1 
ATOM 3307 O O   . ILE B 1 127 ? 112.342 90.974  150.805 1.00 112.69 ?  103  ILE R O   1 
ATOM 3308 C CB  . ILE B 1 127 ? 111.263 91.561  147.699 1.00 112.69 ?  103  ILE R CB  1 
ATOM 3309 C CG1 . ILE B 1 127 ? 110.183 91.690  146.622 1.00 112.69 ?  103  ILE R CG1 1 
ATOM 3310 C CG2 . ILE B 1 127 ? 112.247 90.461  147.325 1.00 112.69 ?  103  ILE R CG2 1 
ATOM 3311 C CD1 . ILE B 1 127 ? 109.244 90.497  146.500 1.00 112.69 ?  103  ILE R CD1 1 
ATOM 3312 N N   . GLY B 1 128 ? 111.691 93.084  150.432 1.00 114.44 ?  104  GLY R N   1 
ATOM 3313 C CA  . GLY B 1 128 ? 112.535 93.619  151.481 1.00 114.44 ?  104  GLY R CA  1 
ATOM 3314 C C   . GLY B 1 128 ? 114.011 93.374  151.254 1.00 114.44 ?  104  GLY R C   1 
ATOM 3315 O O   . GLY B 1 128 ? 114.727 92.948  152.165 1.00 114.44 ?  104  GLY R O   1 
ATOM 3316 N N   . SER B 1 129 ? 114.475 93.637  150.040 1.00 111.16 ?  105  SER R N   1 
ATOM 3317 C CA  . SER B 1 129 ? 115.862 93.430  149.662 1.00 111.16 ?  105  SER R CA  1 
ATOM 3318 C C   . SER B 1 129 ? 116.543 94.770  149.418 1.00 111.16 ?  105  SER R C   1 
ATOM 3319 O O   . SER B 1 129 ? 115.915 95.730  148.964 1.00 111.16 ?  105  SER R O   1 
ATOM 3320 C CB  . SER B 1 129 ? 115.957 92.563  148.408 1.00 111.16 ?  105  SER R CB  1 
ATOM 3321 O OG  . SER B 1 129 ? 115.465 93.270  147.285 1.00 111.16 ?  105  SER R OG  1 
ATOM 3322 N N   . ALA B 1 130 ? 117.837 94.826  149.726 1.00 113.70 ?  106  ALA R N   1 
ATOM 3323 C CA  . ALA B 1 130 ? 118.613 96.054  149.601 1.00 113.70 ?  106  ALA R CA  1 
ATOM 3324 C C   . ALA B 1 130 ? 119.387 96.135  148.291 1.00 113.70 ?  106  ALA R C   1 
ATOM 3325 O O   . ALA B 1 130 ? 119.312 97.148  147.591 1.00 113.70 ?  106  ALA R O   1 
ATOM 3326 C CB  . ALA B 1 130 ? 119.579 96.187  150.784 1.00 113.70 ?  106  ALA R CB  1 
ATOM 3327 N N   . GLU B 1 131 ? 120.136 95.085  147.947 1.00 115.06 ?  107  GLU R N   1 
ATOM 3328 C CA  . GLU B 1 131 ? 120.947 95.121  146.733 1.00 115.06 ?  107  GLU R CA  1 
ATOM 3329 C C   . GLU B 1 131 ? 120.079 95.183  145.483 1.00 115.06 ?  107  GLU R C   1 
ATOM 3330 O O   . GLU B 1 131 ? 120.415 95.886  144.518 1.00 115.06 ?  107  GLU R O   1 
ATOM 3331 C CB  . GLU B 1 131 ? 121.872 93.905  146.687 1.00 115.06 ?  107  GLU R CB  1 
ATOM 3332 C CG  . GLU B 1 131 ? 123.135 94.052  147.522 1.00 115.06 ?  107  GLU R CG  1 
ATOM 3333 C CD  . GLU B 1 131 ? 122.869 93.955  149.012 1.00 115.06 ?  107  GLU R CD  1 
ATOM 3334 O OE1 . GLU B 1 131 ? 121.820 93.396  149.396 1.00 115.06 ?  107  GLU R OE1 1 
ATOM 3335 O OE2 . GLU B 1 131 ? 123.709 94.441  149.799 1.00 115.06 -1 107  GLU R OE2 1 
ATOM 3336 N N   . MET B 1 132 ? 118.963 94.450  145.478 1.00 112.59 ?  108  MET R N   1 
ATOM 3337 C CA  . MET B 1 132 ? 118.102 94.426  144.302 1.00 112.59 ?  108  MET R CA  1 
ATOM 3338 C C   . MET B 1 132 ? 117.524 95.804  144.008 1.00 112.59 ?  108  MET R C   1 
ATOM 3339 O O   . MET B 1 132 ? 117.444 96.213  142.845 1.00 112.59 ?  108  MET R O   1 
ATOM 3340 C CB  . MET B 1 132 ? 116.995 93.391  144.483 1.00 112.59 ?  108  MET R CB  1 
ATOM 3341 C CG  . MET B 1 132 ? 117.454 92.124  145.182 1.00 112.59 ?  108  MET R CG  1 
ATOM 3342 S SD  . MET B 1 132 ? 119.205 91.782  144.925 1.00 112.59 ?  108  MET R SD  1 
ATOM 3343 C CE  . MET B 1 132 ? 119.138 90.748  143.464 1.00 112.59 ?  108  MET R CE  1 
ATOM 3344 N N   . SER B 1 133 ? 117.128 96.542  145.046 1.00 106.65 ?  109  SER R N   1 
ATOM 3345 C CA  . SER B 1 133 ? 116.638 97.900  144.831 1.00 106.65 ?  109  SER R CA  1 
ATOM 3346 C C   . SER B 1 133 ? 117.724 98.786  144.232 1.00 106.65 ?  109  SER R C   1 
ATOM 3347 O O   . SER B 1 133 ? 117.450 99.613  143.350 1.00 106.65 ?  109  SER R O   1 
ATOM 3348 C CB  . SER B 1 133 ? 116.128 98.488  146.146 1.00 106.65 ?  109  SER R CB  1 
ATOM 3349 O OG  . SER B 1 133 ? 117.184 98.644  147.077 1.00 106.65 ?  109  SER R OG  1 
ATOM 3350 N N   . LEU B 1 134 ? 118.963 98.624  144.697 1.00 99.55  ?  110  LEU R N   1 
ATOM 3351 C CA  . LEU B 1 134 ? 120.069 99.407  144.160 1.00 99.55  ?  110  LEU R CA  1 
ATOM 3352 C C   . LEU B 1 134 ? 120.271 99.129  142.675 1.00 99.55  ?  110  LEU R C   1 
ATOM 3353 O O   . LEU B 1 134 ? 120.337 100.058 141.857 1.00 99.55  ?  110  LEU R O   1 
ATOM 3354 C CB  . LEU B 1 134 ? 121.343 99.104  144.944 1.00 99.55  ?  110  LEU R CB  1 
ATOM 3355 C CG  . LEU B 1 134 ? 122.460 100.143 144.856 1.00 99.55  ?  110  LEU R CG  1 
ATOM 3356 C CD1 . LEU B 1 134 ? 122.150 101.335 145.744 1.00 99.55  ?  110  LEU R CD1 1 
ATOM 3357 C CD2 . LEU B 1 134 ? 123.797 99.525  145.235 1.00 99.55  ?  110  LEU R CD2 1 
ATOM 3358 N N   . VAL B 1 135 ? 120.363 97.851  142.302 1.00 99.32  ?  111  VAL R N   1 
ATOM 3359 C CA  . VAL B 1 135 ? 120.597 97.553  140.893 1.00 99.32  ?  111  VAL R CA  1 
ATOM 3360 C C   . VAL B 1 135 ? 119.393 97.954  140.051 1.00 99.32  ?  111  VAL R C   1 
ATOM 3361 O O   . VAL B 1 135 ? 119.543 98.323  138.880 1.00 99.32  ?  111  VAL R O   1 
ATOM 3362 C CB  . VAL B 1 135 ? 120.966 96.073  140.685 1.00 99.32  ?  111  VAL R CB  1 
ATOM 3363 C CG1 . VAL B 1 135 ? 122.398 95.813  141.133 1.00 99.32  ?  111  VAL R CG1 1 
ATOM 3364 C CG2 . VAL B 1 135 ? 119.998 95.163  141.402 1.00 99.32  ?  111  VAL R CG2 1 
ATOM 3365 N N   . LEU B 1 136 ? 118.188 97.918  140.624 1.00 99.26  ?  112  LEU R N   1 
ATOM 3366 C CA  . LEU B 1 136 ? 117.009 98.308  139.860 1.00 99.26  ?  112  LEU R CA  1 
ATOM 3367 C C   . LEU B 1 136 ? 116.987 99.809  139.591 1.00 99.26  ?  112  LEU R C   1 
ATOM 3368 O O   . LEU B 1 136 ? 116.660 100.240 138.479 1.00 99.26  ?  112  LEU R O   1 
ATOM 3369 C CB  . LEU B 1 136 ? 115.745 97.861  140.590 1.00 99.26  ?  112  LEU R CB  1 
ATOM 3370 C CG  . LEU B 1 136 ? 115.415 96.386  140.357 1.00 99.26  ?  112  LEU R CG  1 
ATOM 3371 C CD1 . LEU B 1 136 ? 114.337 95.898  141.311 1.00 99.26  ?  112  LEU R CD1 1 
ATOM 3372 C CD2 . LEU B 1 136 ? 115.008 96.155  138.910 1.00 99.26  ?  112  LEU R CD2 1 
ATOM 3373 N N   . VAL B 1 137 ? 117.334 100.627 140.587 1.00 94.54  ?  113  VAL R N   1 
ATOM 3374 C CA  . VAL B 1 137 ? 117.393 102.061 140.314 1.00 94.54  ?  113  VAL R CA  1 
ATOM 3375 C C   . VAL B 1 137 ? 118.520 102.363 139.330 1.00 94.54  ?  113  VAL R C   1 
ATOM 3376 O O   . VAL B 1 137 ? 118.389 103.250 138.466 1.00 94.54  ?  113  VAL R O   1 
ATOM 3377 C CB  . VAL B 1 137 ? 117.515 102.871 141.620 1.00 94.54  ?  113  VAL R CB  1 
ATOM 3378 C CG1 . VAL B 1 137 ? 118.912 102.788 142.207 1.00 94.54  ?  113  VAL R CG1 1 
ATOM 3379 C CG2 . VAL B 1 137 ? 117.119 104.320 141.380 1.00 94.54  ?  113  VAL R CG2 1 
ATOM 3380 N N   . GLY B 1 138 ? 119.622 101.612 139.408 1.00 89.13  ?  114  GLY R N   1 
ATOM 3381 C CA  . GLY B 1 138 ? 120.684 101.790 138.432 1.00 89.13  ?  114  GLY R CA  1 
ATOM 3382 C C   . GLY B 1 138 ? 120.232 101.498 137.013 1.00 89.13  ?  114  GLY R C   1 
ATOM 3383 O O   . GLY B 1 138 ? 120.505 102.269 136.087 1.00 89.13  ?  114  GLY R O   1 
ATOM 3384 N N   . VAL B 1 139 ? 119.528 100.380 136.822 1.00 82.62  ?  115  VAL R N   1 
ATOM 3385 C CA  . VAL B 1 139 ? 119.085 100.034 135.476 1.00 82.62  ?  115  VAL R CA  1 
ATOM 3386 C C   . VAL B 1 139 ? 118.002 100.999 135.009 1.00 82.62  ?  115  VAL R C   1 
ATOM 3387 O O   . VAL B 1 139 ? 117.856 101.243 133.805 1.00 82.62  ?  115  VAL R O   1 
ATOM 3388 C CB  . VAL B 1 139 ? 118.625 98.564  135.414 1.00 82.62  ?  115  VAL R CB  1 
ATOM 3389 C CG1 . VAL B 1 139 ? 117.380 98.338  136.237 1.00 82.62  ?  115  VAL R CG1 1 
ATOM 3390 C CG2 . VAL B 1 139 ? 118.426 98.120  133.981 1.00 82.62  ?  115  VAL R CG2 1 
ATOM 3391 N N   . LEU B 1 140 ? 117.242 101.581 135.939 1.00 77.24  ?  116  LEU R N   1 
ATOM 3392 C CA  . LEU B 1 140 ? 116.284 102.615 135.557 1.00 77.24  ?  116  LEU R CA  1 
ATOM 3393 C C   . LEU B 1 140 ? 116.995 103.831 134.973 1.00 77.24  ?  116  LEU R C   1 
ATOM 3394 O O   . LEU B 1 140 ? 116.591 104.367 133.927 1.00 77.24  ?  116  LEU R O   1 
ATOM 3395 C CB  . LEU B 1 140 ? 115.443 103.012 136.768 1.00 77.24  ?  116  LEU R CB  1 
ATOM 3396 C CG  . LEU B 1 140 ? 114.008 103.449 136.492 1.00 77.24  ?  116  LEU R CG  1 
ATOM 3397 C CD1 . LEU B 1 140 ? 113.165 102.257 136.084 1.00 77.24  ?  116  LEU R CD1 1 
ATOM 3398 C CD2 . LEU B 1 140 ? 113.417 104.130 137.712 1.00 77.24  ?  116  LEU R CD2 1 
ATOM 3399 N N   . ALA B 1 141 ? 118.058 104.284 135.641 1.00 76.19  ?  117  ALA R N   1 
ATOM 3400 C CA  . ALA B 1 141 ? 118.832 105.401 135.103 1.00 76.19  ?  117  ALA R CA  1 
ATOM 3401 C C   . ALA B 1 141 ? 119.436 105.041 133.752 1.00 76.19  ?  117  ALA R C   1 
ATOM 3402 O O   . ALA B 1 141 ? 119.438 105.857 132.815 1.00 76.19  ?  117  ALA R O   1 
ATOM 3403 C CB  . ALA B 1 141 ? 119.924 105.812 136.088 1.00 76.19  ?  117  ALA R CB  1 
ATOM 3404 N N   . MET B 1 142 ? 119.968 103.822 133.649 1.00 80.51  ?  118  MET R N   1 
ATOM 3405 C CA  . MET B 1 142 ? 120.424 103.264 132.381 1.00 80.51  ?  118  MET R CA  1 
ATOM 3406 C C   . MET B 1 142 ? 119.400 103.484 131.277 1.00 80.51  ?  118  MET R C   1 
ATOM 3407 O O   . MET B 1 142 ? 119.701 104.051 130.217 1.00 80.51  ?  118  MET R O   1 
ATOM 3408 C CB  . MET B 1 142 ? 120.674 101.767 132.569 1.00 80.51  ?  118  MET R CB  1 
ATOM 3409 C CG  . MET B 1 142 ? 121.181 101.036 131.356 1.00 80.51  ?  118  MET R CG  1 
ATOM 3410 S SD  . MET B 1 142 ? 122.498 101.921 130.539 1.00 80.51  ?  118  MET R SD  1 
ATOM 3411 C CE  . MET B 1 142 ? 123.849 100.858 131.013 1.00 80.51  ?  118  MET R CE  1 
ATOM 3412 N N   . ALA B 1 143 ? 118.175 103.024 131.521 1.00 74.85  ?  119  ALA R N   1 
ATOM 3413 C CA  . ALA B 1 143 ? 117.147 103.049 130.492 1.00 74.85  ?  119  ALA R CA  1 
ATOM 3414 C C   . ALA B 1 143 ? 116.774 104.471 130.101 1.00 74.85  ?  119  ALA R C   1 
ATOM 3415 O O   . ALA B 1 143 ? 116.577 104.759 128.915 1.00 74.85  ?  119  ALA R O   1 
ATOM 3416 C CB  . ALA B 1 143 ? 115.918 102.286 130.971 1.00 74.85  ?  119  ALA R CB  1 
ATOM 3417 N N   . PHE B 1 144 ? 116.652 105.373 131.078 1.00 68.84  ?  120  PHE R N   1 
ATOM 3418 C CA  . PHE B 1 144 ? 116.271 106.741 130.730 1.00 68.84  ?  120  PHE R CA  1 
ATOM 3419 C C   . PHE B 1 144 ? 117.347 107.422 129.890 1.00 68.84  ?  120  PHE R C   1 
ATOM 3420 O O   . PHE B 1 144 ? 117.038 108.116 128.903 1.00 68.84  ?  120  PHE R O   1 
ATOM 3421 C CB  . PHE B 1 144 ? 115.976 107.552 131.987 1.00 68.84  ?  120  PHE R CB  1 
ATOM 3422 C CG  . PHE B 1 144 ? 114.638 107.258 132.589 1.00 68.84  ?  120  PHE R CG  1 
ATOM 3423 C CD1 . PHE B 1 144 ? 113.594 106.828 131.798 1.00 68.84  ?  120  PHE R CD1 1 
ATOM 3424 C CD2 . PHE B 1 144 ? 114.418 107.432 133.942 1.00 68.84  ?  120  PHE R CD2 1 
ATOM 3425 C CE1 . PHE B 1 144 ? 112.363 106.560 132.345 1.00 68.84  ?  120  PHE R CE1 1 
ATOM 3426 C CE2 . PHE B 1 144 ? 113.185 107.167 134.493 1.00 68.84  ?  120  PHE R CE2 1 
ATOM 3427 C CZ  . PHE B 1 144 ? 112.157 106.731 133.693 1.00 68.84  ?  120  PHE R CZ  1 
ATOM 3428 N N   . THR B 1 145 ? 118.617 107.235 130.259 1.00 68.02  ?  121  THR R N   1 
ATOM 3429 C CA  . THR B 1 145 ? 119.690 107.810 129.455 1.00 68.02  ?  121  THR R CA  1 
ATOM 3430 C C   . THR B 1 145 ? 119.682 107.230 128.045 1.00 68.02  ?  121  THR R C   1 
ATOM 3431 O O   . THR B 1 145 ? 119.855 107.962 127.056 1.00 68.02  ?  121  THR R O   1 
ATOM 3432 C CB  . THR B 1 145 ? 121.037 107.576 130.134 1.00 68.02  ?  121  THR R CB  1 
ATOM 3433 O OG1 . THR B 1 145 ? 121.184 108.494 131.223 1.00 68.02  ?  121  THR R OG1 1 
ATOM 3434 C CG2 . THR B 1 145 ? 122.180 107.790 129.153 1.00 68.02  ?  121  THR R CG2 1 
ATOM 3435 N N   . ALA B 1 146 ? 119.456 105.921 127.928 1.00 65.27  ?  122  ALA R N   1 
ATOM 3436 C CA  . ALA B 1 146 ? 119.381 105.308 126.608 1.00 65.27  ?  122  ALA R CA  1 
ATOM 3437 C C   . ALA B 1 146 ? 118.241 105.898 125.790 1.00 65.27  ?  122  ALA R C   1 
ATOM 3438 O O   . ALA B 1 146 ? 118.384 106.120 124.584 1.00 65.27  ?  122  ALA R O   1 
ATOM 3439 C CB  . ALA B 1 146 ? 119.219 103.795 126.740 1.00 65.27  ?  122  ALA R CB  1 
ATOM 3440 N N   . SER B 1 147 ? 117.102 106.162 126.431 1.00 61.29  ?  123  SER R N   1 
ATOM 3441 C CA  . SER B 1 147 ? 115.955 106.710 125.714 1.00 61.29  ?  123  SER R CA  1 
ATOM 3442 C C   . SER B 1 147 ? 116.263 108.087 125.137 1.00 61.29  ?  123  SER R C   1 
ATOM 3443 O O   . SER B 1 147 ? 116.003 108.354 123.952 1.00 61.29  ?  123  SER R O   1 
ATOM 3444 C CB  . SER B 1 147 ? 114.745 106.780 126.641 1.00 61.29  ?  123  SER R CB  1 
ATOM 3445 O OG  . SER B 1 147 ? 113.774 107.674 126.131 1.00 61.29  ?  123  SER R OG  1 
ATOM 3446 N N   . ILE B 1 148 ? 116.817 108.982 125.959 1.00 61.73  ?  124  ILE R N   1 
ATOM 3447 C CA  . ILE B 1 148 ? 117.092 110.325 125.448 1.00 61.73  ?  124  ILE R CA  1 
ATOM 3448 C C   . ILE B 1 148 ? 118.157 110.276 124.353 1.00 61.73  ?  124  ILE R C   1 
ATOM 3449 O O   . ILE B 1 148 ? 118.056 110.978 123.330 1.00 61.73  ?  124  ILE R O   1 
ATOM 3450 C CB  . ILE B 1 148 ? 117.475 111.286 126.589 1.00 61.73  ?  124  ILE R CB  1 
ATOM 3451 C CG1 . ILE B 1 148 ? 118.080 112.568 126.027 1.00 61.73  ?  124  ILE R CG1 1 
ATOM 3452 C CG2 . ILE B 1 148 ? 118.445 110.641 127.548 1.00 61.73  ?  124  ILE R CG2 1 
ATOM 3453 C CD1 . ILE B 1 148 ? 118.069 113.713 127.008 1.00 61.73  ?  124  ILE R CD1 1 
ATOM 3454 N N   . GLY B 1 149 ? 119.177 109.431 124.527 1.00 61.90  ?  125  GLY R N   1 
ATOM 3455 C CA  . GLY B 1 149 ? 120.178 109.289 123.483 1.00 61.90  ?  125  GLY R CA  1 
ATOM 3456 C C   . GLY B 1 149 ? 119.597 108.777 122.177 1.00 61.90  ?  125  GLY R C   1 
ATOM 3457 O O   . GLY B 1 149 ? 119.975 109.236 121.094 1.00 61.90  ?  125  GLY R O   1 
ATOM 3458 N N   . SER B 1 150 ? 118.674 107.819 122.261 1.00 66.12  ?  126  SER R N   1 
ATOM 3459 C CA  . SER B 1 150 ? 118.044 107.294 121.057 1.00 66.12  ?  126  SER R CA  1 
ATOM 3460 C C   . SER B 1 150 ? 117.232 108.369 120.351 1.00 66.12  ?  126  SER R C   1 
ATOM 3461 O O   . SER B 1 150 ? 117.221 108.438 119.115 1.00 66.12  ?  126  SER R O   1 
ATOM 3462 C CB  . SER B 1 150 ? 117.163 106.097 121.409 1.00 66.12  ?  126  SER R CB  1 
ATOM 3463 O OG  . SER B 1 150 ? 116.976 105.255 120.287 1.00 66.12  ?  126  SER R OG  1 
ATOM 3464 N N   . LEU B 1 151 ? 116.539 109.214 121.117 1.00 61.22  ?  127  LEU R N   1 
ATOM 3465 C CA  . LEU B 1 151 ? 115.801 110.313 120.497 1.00 61.22  ?  127  LEU R CA  1 
ATOM 3466 C C   . LEU B 1 151 ? 116.736 111.252 119.743 1.00 61.22  ?  127  LEU R C   1 
ATOM 3467 O O   . LEU B 1 151 ? 116.447 111.660 118.605 1.00 61.22  ?  127  LEU R O   1 
ATOM 3468 C CB  . LEU B 1 151 ? 115.016 111.080 121.556 1.00 61.22  ?  127  LEU R CB  1 
ATOM 3469 C CG  . LEU B 1 151 ? 113.893 111.975 121.041 1.00 61.22  ?  127  LEU R CG  1 
ATOM 3470 C CD1 . LEU B 1 151 ? 112.665 111.830 121.920 1.00 61.22  ?  127  LEU R CD1 1 
ATOM 3471 C CD2 . LEU B 1 151 ? 114.345 113.424 120.985 1.00 61.22  ?  127  LEU R CD2 1 
ATOM 3472 N N   . LEU B 1 152 ? 117.869 111.600 120.359 1.00 57.94  ?  128  LEU R N   1 
ATOM 3473 C CA  . LEU B 1 152 ? 118.822 112.476 119.680 1.00 57.94  ?  128  LEU R CA  1 
ATOM 3474 C C   . LEU B 1 152 ? 119.362 111.828 118.408 1.00 57.94  ?  128  LEU R C   1 
ATOM 3475 O O   . LEU B 1 152 ? 119.509 112.492 117.370 1.00 57.94  ?  128  LEU R O   1 
ATOM 3476 C CB  . LEU B 1 152 ? 119.967 112.839 120.621 1.00 57.94  ?  128  LEU R CB  1 
ATOM 3477 C CG  . LEU B 1 152 ? 121.231 113.369 119.952 1.00 57.94  ?  128  LEU R CG  1 
ATOM 3478 C CD1 . LEU B 1 152 ? 120.992 114.761 119.427 1.00 57.94  ?  128  LEU R CD1 1 
ATOM 3479 C CD2 . LEU B 1 152 ? 122.394 113.358 120.921 1.00 57.94  ?  128  LEU R CD2 1 
ATOM 3480 N N   . ALA B 1 153 ? 119.662 110.530 118.469 1.00 63.68  ?  129  ALA R N   1 
ATOM 3481 C CA  . ALA B 1 153 ? 120.149 109.837 117.281 1.00 63.68  ?  129  ALA R CA  1 
ATOM 3482 C C   . ALA B 1 153 ? 119.106 109.850 116.172 1.00 63.68  ?  129  ALA R C   1 
ATOM 3483 O O   . ALA B 1 153 ? 119.437 110.052 114.996 1.00 63.68  ?  129  ALA R O   1 
ATOM 3484 C CB  . ALA B 1 153 ? 120.543 108.404 117.632 1.00 63.68  ?  129  ALA R CB  1 
ATOM 3485 N N   . ILE B 1 154 ? 117.837 109.640 116.527 1.00 64.18  ?  130  ILE R N   1 
ATOM 3486 C CA  . ILE B 1 154 ? 116.779 109.639 115.521 1.00 64.18  ?  130  ILE R CA  1 
ATOM 3487 C C   . ILE B 1 154 ? 116.703 110.995 114.833 1.00 64.18  ?  130  ILE R C   1 
ATOM 3488 O O   . ILE B 1 154 ? 116.611 111.083 113.599 1.00 64.18  ?  130  ILE R O   1 
ATOM 3489 C CB  . ILE B 1 154 ? 115.433 109.251 116.156 1.00 64.18  ?  130  ILE R CB  1 
ATOM 3490 C CG1 . ILE B 1 154 ? 115.279 107.734 116.183 1.00 64.18  ?  130  ILE R CG1 1 
ATOM 3491 C CG2 . ILE B 1 154 ? 114.285 109.864 115.383 1.00 64.18  ?  130  ILE R CG2 1 
ATOM 3492 C CD1 . ILE B 1 154 ? 113.902 107.266 116.596 1.00 64.18  ?  130  ILE R CD1 1 
ATOM 3493 N N   . THR B 1 155 ? 116.753 112.076 115.615 1.00 58.78  ?  131  THR R N   1 
ATOM 3494 C CA  . THR B 1 155 ? 116.601 113.386 114.987 1.00 58.78  ?  131  THR R CA  1 
ATOM 3495 C C   . THR B 1 155 ? 117.808 113.732 114.119 1.00 58.78  ?  131  THR R C   1 
ATOM 3496 O O   . THR B 1 155 ? 117.651 114.344 113.053 1.00 58.78  ?  131  THR R O   1 
ATOM 3497 C CB  . THR B 1 155 ? 116.344 114.476 116.027 1.00 58.78  ?  131  THR R CB  1 
ATOM 3498 O OG1 . THR B 1 155 ? 115.915 115.667 115.357 1.00 58.78  ?  131  THR R OG1 1 
ATOM 3499 C CG2 . THR B 1 155 ? 117.593 114.800 116.807 1.00 58.78  ?  131  THR R CG2 1 
ATOM 3500 N N   . VAL B 1 156 ? 119.016 113.332 114.530 1.00 60.79  ?  132  VAL R N   1 
ATOM 3501 C CA  . VAL B 1 156 ? 120.175 113.641 113.697 1.00 60.79  ?  132  VAL R CA  1 
ATOM 3502 C C   . VAL B 1 156 ? 120.131 112.832 112.406 1.00 60.79  ?  132  VAL R C   1 
ATOM 3503 O O   . VAL B 1 156 ? 120.504 113.327 111.332 1.00 60.79  ?  132  VAL R O   1 
ATOM 3504 C CB  . VAL B 1 156 ? 121.492 113.437 114.472 1.00 60.79  ?  132  VAL R CB  1 
ATOM 3505 C CG1 . VAL B 1 156 ? 121.838 111.967 114.630 1.00 60.79  ?  132  VAL R CG1 1 
ATOM 3506 C CG2 . VAL B 1 156 ? 122.623 114.176 113.781 1.00 60.79  ?  132  VAL R CG2 1 
ATOM 3507 N N   . ASP B 1 157 ? 119.647 111.588 112.479 1.00 68.83  ?  133  ASP R N   1 
ATOM 3508 C CA  . ASP B 1 157 ? 119.498 110.789 111.270 1.00 68.83  ?  133  ASP R CA  1 
ATOM 3509 C C   . ASP B 1 157 ? 118.510 111.448 110.319 1.00 68.83  ?  133  ASP R C   1 
ATOM 3510 O O   . ASP B 1 157 ? 118.773 111.555 109.115 1.00 68.83  ?  133  ASP R O   1 
ATOM 3511 C CB  . ASP B 1 157 ? 119.053 109.371 111.647 1.00 68.83  ?  133  ASP R CB  1 
ATOM 3512 C CG  . ASP B 1 157 ? 118.259 108.665 110.550 1.00 68.83  ?  133  ASP R CG  1 
ATOM 3513 O OD1 . ASP B 1 157 ? 118.493 108.899 109.346 1.00 68.83  ?  133  ASP R OD1 1 
ATOM 3514 O OD2 . ASP B 1 157 ? 117.378 107.856 110.908 1.00 68.83  -1 133  ASP R OD2 1 
ATOM 3515 N N   . ARG B 1 158 ? 117.376 111.918 110.844 1.00 62.72  ?  134  ARG R N   1 
ATOM 3516 C CA  . ARG B 1 158 ? 116.389 112.567 109.985 1.00 62.72  ?  134  ARG R CA  1 
ATOM 3517 C C   . ARG B 1 158 ? 116.954 113.823 109.336 1.00 62.72  ?  134  ARG R C   1 
ATOM 3518 O O   . ARG B 1 158 ? 116.733 114.068 108.142 1.00 62.72  ?  134  ARG R O   1 
ATOM 3519 C CB  . ARG B 1 158 ? 115.133 112.906 110.783 1.00 62.72  ?  134  ARG R CB  1 
ATOM 3520 C CG  . ARG B 1 158 ? 114.032 113.534 109.951 1.00 62.72  ?  134  ARG R CG  1 
ATOM 3521 C CD  . ARG B 1 158 ? 112.675 112.982 110.339 1.00 62.72  ?  134  ARG R CD  1 
ATOM 3522 N NE  . ARG B 1 158 ? 111.585 113.840 109.893 1.00 62.72  ?  134  ARG R NE  1 
ATOM 3523 C CZ  . ARG B 1 158 ? 111.255 114.992 110.460 1.00 62.72  ?  134  ARG R CZ  1 
ATOM 3524 N NH1 . ARG B 1 158 ? 111.905 115.454 111.516 1.00 62.72  1  134  ARG R NH1 1 
ATOM 3525 N NH2 . ARG B 1 158 ? 110.243 115.695 109.960 1.00 62.72  ?  134  ARG R NH2 1 
ATOM 3526 N N   . TYR B 1 159 ? 117.682 114.636 110.103 1.00 59.67  ?  135  TYR R N   1 
ATOM 3527 C CA  . TYR B 1 159 ? 118.229 115.864 109.537 1.00 59.67  ?  135  TYR R CA  1 
ATOM 3528 C C   . TYR B 1 159 ? 119.242 115.572 108.443 1.00 59.67  ?  135  TYR R C   1 
ATOM 3529 O O   . TYR B 1 159 ? 119.220 116.211 107.385 1.00 59.67  ?  135  TYR R O   1 
ATOM 3530 C CB  . TYR B 1 159 ? 118.872 116.716 110.620 1.00 59.67  ?  135  TYR R CB  1 
ATOM 3531 C CG  . TYR B 1 159 ? 119.838 117.736 110.069 1.00 59.67  ?  135  TYR R CG  1 
ATOM 3532 C CD1 . TYR B 1 159 ? 119.384 118.827 109.356 1.00 59.67  ?  135  TYR R CD1 1 
ATOM 3533 C CD2 . TYR B 1 159 ? 121.201 117.610 110.272 1.00 59.67  ?  135  TYR R CD2 1 
ATOM 3534 C CE1 . TYR B 1 159 ? 120.257 119.762 108.856 1.00 59.67  ?  135  TYR R CE1 1 
ATOM 3535 C CE2 . TYR B 1 159 ? 122.082 118.543 109.775 1.00 59.67  ?  135  TYR R CE2 1 
ATOM 3536 C CZ  . TYR B 1 159 ? 121.603 119.616 109.070 1.00 59.67  ?  135  TYR R CZ  1 
ATOM 3537 O OH  . TYR B 1 159 ? 122.478 120.548 108.570 1.00 59.67  ?  135  TYR R OH  1 
ATOM 3538 N N   . LEU B 1 160 ? 120.150 114.621 108.677 1.00 64.13  ?  136  LEU R N   1 
ATOM 3539 C CA  . LEU B 1 160 ? 121.128 114.300 107.642 1.00 64.13  ?  136  LEU R CA  1 
ATOM 3540 C C   . LEU B 1 160 ? 120.455 113.705 106.414 1.00 64.13  ?  136  LEU R C   1 
ATOM 3541 O O   . LEU B 1 160 ? 120.882 113.958 105.282 1.00 64.13  ?  136  LEU R O   1 
ATOM 3542 C CB  . LEU B 1 160 ? 122.199 113.359 108.185 1.00 64.13  ?  136  LEU R CB  1 
ATOM 3543 C CG  . LEU B 1 160 ? 123.582 113.996 108.335 1.00 64.13  ?  136  LEU R CG  1 
ATOM 3544 C CD1 . LEU B 1 160 ? 123.562 115.106 109.366 1.00 64.13  ?  136  LEU R CD1 1 
ATOM 3545 C CD2 . LEU B 1 160 ? 124.618 112.945 108.696 1.00 64.13  ?  136  LEU R CD2 1 
ATOM 3546 N N   . SER B 1 161 ? 119.401 112.913 106.612 1.00 70.20  ?  137  SER R N   1 
ATOM 3547 C CA  . SER B 1 161 ? 118.679 112.362 105.471 1.00 70.20  ?  137  SER R CA  1 
ATOM 3548 C C   . SER B 1 161 ? 118.036 113.463 104.640 1.00 70.20  ?  137  SER R C   1 
ATOM 3549 O O   . SER B 1 161 ? 118.081 113.424 103.405 1.00 70.20  ?  137  SER R O   1 
ATOM 3550 C CB  . SER B 1 161 ? 117.622 111.368 105.950 1.00 70.20  ?  137  SER R CB  1 
ATOM 3551 O OG  . SER B 1 161 ? 116.703 111.068 104.914 1.00 70.20  ?  137  SER R OG  1 
ATOM 3552 N N   . LEU B 1 162 ? 117.431 114.454 105.293 1.00 66.66  ?  138  LEU R N   1 
ATOM 3553 C CA  . LEU B 1 162 ? 116.769 115.525 104.557 1.00 66.66  ?  138  LEU R CA  1 
ATOM 3554 C C   . LEU B 1 162 ? 117.730 116.592 104.050 1.00 66.66  ?  138  LEU R C   1 
ATOM 3555 O O   . LEU B 1 162 ? 117.325 117.425 103.234 1.00 66.66  ?  138  LEU R O   1 
ATOM 3556 C CB  . LEU B 1 162 ? 115.699 116.181 105.427 1.00 66.66  ?  138  LEU R CB  1 
ATOM 3557 C CG  . LEU B 1 162 ? 114.473 116.688 104.674 1.00 66.66  ?  138  LEU R CG  1 
ATOM 3558 C CD1 . LEU B 1 162 ? 113.788 115.541 103.960 1.00 66.66  ?  138  LEU R CD1 1 
ATOM 3559 C CD2 . LEU B 1 162 ? 113.519 117.365 105.632 1.00 66.66  ?  138  LEU R CD2 1 
ATOM 3560 N N   . TYR B 1 163 ? 118.977 116.601 104.518 1.00 71.90  ?  139  TYR R N   1 
ATOM 3561 C CA  . TYR B 1 163 ? 119.943 117.585 104.044 1.00 71.90  ?  139  TYR R CA  1 
ATOM 3562 C C   . TYR B 1 163 ? 120.309 117.326 102.591 1.00 71.90  ?  139  TYR R C   1 
ATOM 3563 O O   . TYR B 1 163 ? 120.108 118.181 101.722 1.00 71.90  ?  139  TYR R O   1 
ATOM 3564 C CB  . TYR B 1 163 ? 121.186 117.552 104.931 1.00 71.90  ?  139  TYR R CB  1 
ATOM 3565 C CG  . TYR B 1 163 ? 122.334 118.409 104.454 1.00 71.90  ?  139  TYR R CG  1 
ATOM 3566 C CD1 . TYR B 1 163 ? 122.391 119.757 104.763 1.00 71.90  ?  139  TYR R CD1 1 
ATOM 3567 C CD2 . TYR B 1 163 ? 123.372 117.864 103.716 1.00 71.90  ?  139  TYR R CD2 1 
ATOM 3568 C CE1 . TYR B 1 163 ? 123.442 120.539 104.344 1.00 71.90  ?  139  TYR R CE1 1 
ATOM 3569 C CE2 . TYR B 1 163 ? 124.425 118.637 103.293 1.00 71.90  ?  139  TYR R CE2 1 
ATOM 3570 C CZ  . TYR B 1 163 ? 124.456 119.975 103.609 1.00 71.90  ?  139  TYR R CZ  1 
ATOM 3571 O OH  . TYR B 1 163 ? 125.506 120.754 103.184 1.00 71.90  ?  139  TYR R OH  1 
ATOM 3572 N N   . ASN B 1 164 ? 120.853 116.147 102.310 1.00 86.95  ?  140  ASN R N   1 
ATOM 3573 C CA  . ASN B 1 164 ? 121.137 115.708 100.953 1.00 86.95  ?  140  ASN R CA  1 
ATOM 3574 C C   . ASN B 1 164 ? 120.359 114.432 100.674 1.00 86.95  ?  140  ASN R C   1 
ATOM 3575 O O   . ASN B 1 164 ? 120.253 113.558 101.539 1.00 86.95  ?  140  ASN R O   1 
ATOM 3576 C CB  . ASN B 1 164 ? 122.640 115.487 100.739 1.00 86.95  ?  140  ASN R CB  1 
ATOM 3577 C CG  . ASN B 1 164 ? 123.185 114.321 101.541 1.00 86.95  ?  140  ASN R CG  1 
ATOM 3578 O OD1 . ASN B 1 164 ? 122.941 113.159 101.219 1.00 86.95  ?  140  ASN R OD1 1 
ATOM 3579 N ND2 . ASN B 1 164 ? 123.931 114.630 102.594 1.00 86.95  ?  140  ASN R ND2 1 
ATOM 3580 N N   . ALA B 1 165 ? 119.798 114.337 99.473  1.00 101.58 ?  141  ALA R N   1 
ATOM 3581 C CA  . ALA B 1 165 ? 118.998 113.179 99.097  1.00 101.58 ?  141  ALA R CA  1 
ATOM 3582 C C   . ALA B 1 165 ? 119.735 112.204 98.190  1.00 101.58 ?  141  ALA R C   1 
ATOM 3583 O O   . ALA B 1 165 ? 119.389 111.019 98.166  1.00 101.58 ?  141  ALA R O   1 
ATOM 3584 C CB  . ALA B 1 165 ? 117.706 113.629 98.406  1.00 101.58 ?  141  ALA R CB  1 
ATOM 3585 N N   . LEU B 1 166 ? 120.738 112.672 97.444  1.00 121.89 ?  142  LEU R N   1 
ATOM 3586 C CA  . LEU B 1 166 ? 121.432 111.795 96.506  1.00 121.89 ?  142  LEU R CA  1 
ATOM 3587 C C   . LEU B 1 166 ? 122.338 110.801 97.225  1.00 121.89 ?  142  LEU R C   1 
ATOM 3588 O O   . LEU B 1 166 ? 122.349 109.611 96.892  1.00 121.89 ?  142  LEU R O   1 
ATOM 3589 C CB  . LEU B 1 166 ? 122.240 112.627 95.510  1.00 121.89 ?  142  LEU R CB  1 
ATOM 3590 C CG  . LEU B 1 166 ? 121.454 113.575 94.601  1.00 121.89 ?  142  LEU R CG  1 
ATOM 3591 C CD1 . LEU B 1 166 ? 121.520 115.003 95.122  1.00 121.89 ?  142  LEU R CD1 1 
ATOM 3592 C CD2 . LEU B 1 166 ? 121.968 113.497 93.172  1.00 121.89 ?  142  LEU R CD2 1 
ATOM 3593 N N   . THR B 1 167 ? 123.101 111.267 98.213  1.00 119.33 ?  143  THR R N   1 
ATOM 3594 C CA  . THR B 1 167 ? 124.119 110.453 98.864  1.00 119.33 ?  143  THR R CA  1 
ATOM 3595 C C   . THR B 1 167 ? 123.630 109.800 100.151 1.00 119.33 ?  143  THR R C   1 
ATOM 3596 O O   . THR B 1 167 ? 124.425 109.154 100.842 1.00 119.33 ?  143  THR R O   1 
ATOM 3597 C CB  . THR B 1 167 ? 125.362 111.297 99.157  1.00 119.33 ?  143  THR R CB  1 
ATOM 3598 O OG1 . THR B 1 167 ? 125.068 112.237 100.198 1.00 119.33 ?  143  THR R OG1 1 
ATOM 3599 C CG2 . THR B 1 167 ? 125.797 112.056 97.912  1.00 119.33 ?  143  THR R CG2 1 
ATOM 3600 N N   . TYR B 1 168 ? 122.349 109.956 100.493 1.00 120.04 ?  144  TYR R N   1 
ATOM 3601 C CA  . TYR B 1 168 ? 121.848 109.384 101.739 1.00 120.04 ?  144  TYR R CA  1 
ATOM 3602 C C   . TYR B 1 168 ? 121.894 107.861 101.717 1.00 120.04 ?  144  TYR R C   1 
ATOM 3603 O O   . TYR B 1 168 ? 122.260 107.233 102.717 1.00 120.04 ?  144  TYR R O   1 
ATOM 3604 C CB  . TYR B 1 168 ? 120.424 109.870 102.012 1.00 120.04 ?  144  TYR R CB  1 
ATOM 3605 C CG  . TYR B 1 168 ? 119.722 109.093 103.103 1.00 120.04 ?  144  TYR R CG  1 
ATOM 3606 C CD1 . TYR B 1 168 ? 120.169 109.146 104.418 1.00 120.04 ?  144  TYR R CD1 1 
ATOM 3607 C CD2 . TYR B 1 168 ? 118.614 108.305 102.820 1.00 120.04 ?  144  TYR R CD2 1 
ATOM 3608 C CE1 . TYR B 1 168 ? 119.532 108.436 105.419 1.00 120.04 ?  144  TYR R CE1 1 
ATOM 3609 C CE2 . TYR B 1 168 ? 117.970 107.592 103.815 1.00 120.04 ?  144  TYR R CE2 1 
ATOM 3610 C CZ  . TYR B 1 168 ? 118.433 107.662 105.112 1.00 120.04 ?  144  TYR R CZ  1 
ATOM 3611 O OH  . TYR B 1 168 ? 117.796 106.954 106.106 1.00 120.04 ?  144  TYR R OH  1 
ATOM 3612 N N   . TYR B 1 169 ? 121.527 107.248 100.592 1.00 134.24 ?  145  TYR R N   1 
ATOM 3613 C CA  . TYR B 1 169 ? 121.468 105.790 100.484 1.00 134.24 ?  145  TYR R CA  1 
ATOM 3614 C C   . TYR B 1 169 ? 122.828 105.279 100.023 1.00 134.24 ?  145  TYR R C   1 
ATOM 3615 O O   . TYR B 1 169 ? 123.133 105.241 98.830  1.00 134.24 ?  145  TYR R O   1 
ATOM 3616 C CB  . TYR B 1 169 ? 120.354 105.366 99.536  1.00 134.24 ?  145  TYR R CB  1 
ATOM 3617 C CG  . TYR B 1 169 ? 118.970 105.458 100.140 1.00 134.24 ?  145  TYR R CG  1 
ATOM 3618 C CD1 . TYR B 1 169 ? 118.541 104.534 101.084 1.00 134.24 ?  145  TYR R CD1 1 
ATOM 3619 C CD2 . TYR B 1 169 ? 118.093 106.469 99.767  1.00 134.24 ?  145  TYR R CD2 1 
ATOM 3620 C CE1 . TYR B 1 169 ? 117.277 104.614 101.640 1.00 134.24 ?  145  TYR R CE1 1 
ATOM 3621 C CE2 . TYR B 1 169 ? 116.828 106.557 100.318 1.00 134.24 ?  145  TYR R CE2 1 
ATOM 3622 C CZ  . TYR B 1 169 ? 116.425 105.627 101.253 1.00 134.24 ?  145  TYR R CZ  1 
ATOM 3623 O OH  . TYR B 1 169 ? 115.167 105.710 101.804 1.00 134.24 ?  145  TYR R OH  1 
ATOM 3624 N N   . SER B 1 170 ? 123.652 104.876 100.986 1.00 135.88 ?  146  SER R N   1 
ATOM 3625 C CA  . SER B 1 170 ? 124.979 104.338 100.712 1.00 135.88 ?  146  SER R CA  1 
ATOM 3626 C C   . SER B 1 170 ? 125.445 103.573 101.945 1.00 135.88 ?  146  SER R C   1 
ATOM 3627 O O   . SER B 1 170 ? 124.674 103.329 102.876 1.00 135.88 ?  146  SER R O   1 
ATOM 3628 C CB  . SER B 1 170 ? 125.964 105.449 100.334 1.00 135.88 ?  146  SER R CB  1 
ATOM 3629 O OG  . SER B 1 170 ? 125.655 105.997 99.064  1.00 135.88 ?  146  SER R OG  1 
ATOM 3630 N N   . GLU B 1 171 ? 126.719 103.175 101.936 1.00 134.72 ?  147  GLU R N   1 
ATOM 3631 C CA  . GLU B 1 171 ? 127.307 102.550 103.115 1.00 134.72 ?  147  GLU R CA  1 
ATOM 3632 C C   . GLU B 1 171 ? 127.692 103.572 104.177 1.00 134.72 ?  147  GLU R C   1 
ATOM 3633 O O   . GLU B 1 171 ? 127.832 103.207 105.352 1.00 134.72 ?  147  GLU R O   1 
ATOM 3634 C CB  . GLU B 1 171 ? 128.528 101.719 102.717 1.00 134.72 ?  147  GLU R CB  1 
ATOM 3635 C CG  . GLU B 1 171 ? 129.610 102.506 101.994 1.00 134.72 ?  147  GLU R CG  1 
ATOM 3636 C CD  . GLU B 1 171 ? 130.727 102.951 102.917 1.00 134.72 ?  147  GLU R CD  1 
ATOM 3637 O OE1 . GLU B 1 171 ? 130.845 102.386 104.025 1.00 134.72 ?  147  GLU R OE1 1 
ATOM 3638 O OE2 . GLU B 1 171 ? 131.487 103.865 102.535 1.00 134.72 -1 147  GLU R OE2 1 
ATOM 3639 N N   . THR B 1 172 ? 127.859 104.839 103.790 1.00 128.41 ?  148  THR R N   1 
ATOM 3640 C CA  . THR B 1 172 ? 128.257 105.865 104.749 1.00 128.41 ?  148  THR R CA  1 
ATOM 3641 C C   . THR B 1 172 ? 127.217 106.021 105.849 1.00 128.41 ?  148  THR R C   1 
ATOM 3642 O O   . THR B 1 172 ? 127.565 106.148 107.030 1.00 128.41 ?  148  THR R O   1 
ATOM 3643 C CB  . THR B 1 172 ? 128.482 107.196 104.034 1.00 128.41 ?  148  THR R CB  1 
ATOM 3644 O OG1 . THR B 1 172 ? 129.231 106.975 102.832 1.00 128.41 ?  148  THR R OG1 1 
ATOM 3645 C CG2 . THR B 1 172 ? 129.247 108.158 104.930 1.00 128.41 ?  148  THR R CG2 1 
ATOM 3646 N N   . THR B 1 173 ? 125.932 106.011 105.485 1.00 123.07 ?  149  THR R N   1 
ATOM 3647 C CA  . THR B 1 173 ? 124.894 106.071 106.506 1.00 123.07 ?  149  THR R CA  1 
ATOM 3648 C C   . THR B 1 173 ? 124.890 104.815 107.366 1.00 123.07 ?  149  THR R C   1 
ATOM 3649 O O   . THR B 1 173 ? 124.502 104.875 108.535 1.00 123.07 ?  149  THR R O   1 
ATOM 3650 C CB  . THR B 1 173 ? 123.518 106.286 105.872 1.00 123.07 ?  149  THR R CB  1 
ATOM 3651 O OG1 . THR B 1 173 ? 122.521 106.324 106.901 1.00 123.07 ?  149  THR R OG1 1 
ATOM 3652 C CG2 . THR B 1 173 ? 123.187 105.158 104.915 1.00 123.07 ?  149  THR R CG2 1 
ATOM 3653 N N   . VAL B 1 174 ? 125.335 103.680 106.823 1.00 113.79 ?  150  VAL R N   1 
ATOM 3654 C CA  . VAL B 1 174 ? 125.434 102.466 107.627 1.00 113.79 ?  150  VAL R CA  1 
ATOM 3655 C C   . VAL B 1 174 ? 126.511 102.621 108.693 1.00 113.79 ?  150  VAL R C   1 
ATOM 3656 O O   . VAL B 1 174 ? 126.300 102.292 109.869 1.00 113.79 ?  150  VAL R O   1 
ATOM 3657 C CB  . VAL B 1 174 ? 125.696 101.245 106.729 1.00 113.79 ?  150  VAL R CB  1 
ATOM 3658 C CG1 . VAL B 1 174 ? 126.030 100.031 107.575 1.00 113.79 ?  150  VAL R CG1 1 
ATOM 3659 C CG2 . VAL B 1 174 ? 124.486 100.970 105.857 1.00 113.79 ?  150  VAL R CG2 1 
ATOM 3660 N N   . THR B 1 175 ? 127.681 103.131 108.300 1.00 111.63 ?  151  THR R N   1 
ATOM 3661 C CA  . THR B 1 175 ? 128.721 103.390 109.292 1.00 111.63 ?  151  THR R CA  1 
ATOM 3662 C C   . THR B 1 175 ? 128.253 104.414 110.317 1.00 111.63 ?  151  THR R C   1 
ATOM 3663 O O   . THR B 1 175 ? 128.511 104.265 111.517 1.00 111.63 ?  151  THR R O   1 
ATOM 3664 C CB  . THR B 1 175 ? 130.014 103.864 108.622 1.00 111.63 ?  151  THR R CB  1 
ATOM 3665 O OG1 . THR B 1 175 ? 129.970 105.285 108.434 1.00 111.63 ?  151  THR R OG1 1 
ATOM 3666 C CG2 . THR B 1 175 ? 130.227 103.171 107.289 1.00 111.63 ?  151  THR R CG2 1 
ATOM 3667 N N   . ARG B 1 176 ? 127.560 105.459 109.861 1.00 104.35 ?  152  ARG R N   1 
ATOM 3668 C CA  . ARG B 1 176 ? 127.053 106.467 110.784 1.00 104.35 ?  152  ARG R CA  1 
ATOM 3669 C C   . ARG B 1 176 ? 126.069 105.862 111.776 1.00 104.35 ?  152  ARG R C   1 
ATOM 3670 O O   . ARG B 1 176 ? 126.116 106.167 112.973 1.00 104.35 ?  152  ARG R O   1 
ATOM 3671 C CB  . ARG B 1 176 ? 126.396 107.607 110.005 1.00 104.35 ?  152  ARG R CB  1 
ATOM 3672 C CG  . ARG B 1 176 ? 127.316 108.784 109.717 1.00 104.35 ?  152  ARG R CG  1 
ATOM 3673 C CD  . ARG B 1 176 ? 127.678 109.533 110.986 1.00 104.35 ?  152  ARG R CD  1 
ATOM 3674 N NE  . ARG B 1 176 ? 128.497 110.705 110.704 1.00 104.35 ?  152  ARG R NE  1 
ATOM 3675 C CZ  . ARG B 1 176 ? 128.959 111.537 111.627 1.00 104.35 ?  152  ARG R CZ  1 
ATOM 3676 N NH1 . ARG B 1 176 ? 128.699 111.360 112.911 1.00 104.35 1  152  ARG R NH1 1 
ATOM 3677 N NH2 . ARG B 1 176 ? 129.702 112.574 111.251 1.00 104.35 ?  152  ARG R NH2 1 
ATOM 3678 N N   . THR B 1 177 ? 125.167 105.002 111.296 1.00 100.90 ?  153  THR R N   1 
ATOM 3679 C CA  . THR B 1 177 ? 124.190 104.371 112.174 1.00 100.90 ?  153  THR R CA  1 
ATOM 3680 C C   . THR B 1 177 ? 124.871 103.490 113.208 1.00 100.90 ?  153  THR R C   1 
ATOM 3681 O O   . THR B 1 177 ? 124.531 103.536 114.399 1.00 100.90 ?  153  THR R O   1 
ATOM 3682 C CB  . THR B 1 177 ? 123.202 103.552 111.344 1.00 100.90 ?  153  THR R CB  1 
ATOM 3683 O OG1 . THR B 1 177 ? 122.401 104.429 110.544 1.00 100.90 ?  153  THR R OG1 1 
ATOM 3684 C CG2 . THR B 1 177 ? 122.301 102.724 112.243 1.00 100.90 ?  153  THR R CG2 1 
ATOM 3685 N N   . TYR B 1 178 ? 125.840 102.683 112.772 1.00 103.75 ?  154  TYR R N   1 
ATOM 3686 C CA  . TYR B 1 178 ? 126.549 101.820 113.708 1.00 103.75 ?  154  TYR R CA  1 
ATOM 3687 C C   . TYR B 1 178 ? 127.287 102.641 114.756 1.00 103.75 ?  154  TYR R C   1 
ATOM 3688 O O   . TYR B 1 178 ? 127.227 102.334 115.955 1.00 103.75 ?  154  TYR R O   1 
ATOM 3689 C CB  . TYR B 1 178 ? 127.514 100.916 112.947 1.00 103.75 ?  154  TYR R CB  1 
ATOM 3690 C CG  . TYR B 1 178 ? 126.842 99.724  112.312 1.00 103.75 ?  154  TYR R CG  1 
ATOM 3691 C CD1 . TYR B 1 178 ? 125.548 99.368  112.660 1.00 103.75 ?  154  TYR R CD1 1 
ATOM 3692 C CD2 . TYR B 1 178 ? 127.495 98.964  111.352 1.00 103.75 ?  154  TYR R CD2 1 
ATOM 3693 C CE1 . TYR B 1 178 ? 124.926 98.281  112.082 1.00 103.75 ?  154  TYR R CE1 1 
ATOM 3694 C CE2 . TYR B 1 178 ? 126.881 97.876  110.766 1.00 103.75 ?  154  TYR R CE2 1 
ATOM 3695 C CZ  . TYR B 1 178 ? 125.596 97.539  111.134 1.00 103.75 ?  154  TYR R CZ  1 
ATOM 3696 O OH  . TYR B 1 178 ? 124.980 96.455  110.553 1.00 103.75 ?  154  TYR R OH  1 
ATOM 3697 N N   . VAL B 1 179 ? 127.970 103.704 114.325 1.00 99.43  ?  155  VAL R N   1 
ATOM 3698 C CA  . VAL B 1 179 ? 128.719 104.536 115.260 1.00 99.43  ?  155  VAL R CA  1 
ATOM 3699 C C   . VAL B 1 179 ? 127.780 105.202 116.255 1.00 99.43  ?  155  VAL R C   1 
ATOM 3700 O O   . VAL B 1 179 ? 128.062 105.248 117.457 1.00 99.43  ?  155  VAL R O   1 
ATOM 3701 C CB  . VAL B 1 179 ? 129.567 105.568 114.496 1.00 99.43  ?  155  VAL R CB  1 
ATOM 3702 C CG1 . VAL B 1 179 ? 130.061 106.653 115.435 1.00 99.43  ?  155  VAL R CG1 1 
ATOM 3703 C CG2 . VAL B 1 179 ? 130.738 104.884 113.813 1.00 99.43  ?  155  VAL R CG2 1 
ATOM 3704 N N   . MET B 1 180 ? 126.647 105.723 115.778 1.00 103.13 ?  156  MET R N   1 
ATOM 3705 C CA  . MET B 1 180 ? 125.700 106.382 116.672 1.00 103.13 ?  156  MET R CA  1 
ATOM 3706 C C   . MET B 1 180 ? 125.129 105.411 117.697 1.00 103.13 ?  156  MET R C   1 
ATOM 3707 O O   . MET B 1 180 ? 125.036 105.737 118.886 1.00 103.13 ?  156  MET R O   1 
ATOM 3708 C CB  . MET B 1 180 ? 124.578 107.036 115.865 1.00 103.13 ?  156  MET R CB  1 
ATOM 3709 C CG  . MET B 1 180 ? 124.962 108.362 115.241 1.00 103.13 ?  156  MET R CG  1 
ATOM 3710 S SD  . MET B 1 180 ? 125.846 109.395 116.424 1.00 103.13 ?  156  MET R SD  1 
ATOM 3711 C CE  . MET B 1 180 ? 126.954 110.289 115.344 1.00 103.13 ?  156  MET R CE  1 
ATOM 3712 N N   . LEU B 1 181 ? 124.730 104.216 117.256 1.00 89.10  ?  157  LEU R N   1 
ATOM 3713 C CA  . LEU B 1 181 ? 124.176 103.245 118.195 1.00 89.10  ?  157  LEU R CA  1 
ATOM 3714 C C   . LEU B 1 181 ? 125.206 102.855 119.246 1.00 89.10  ?  157  LEU R C   1 
ATOM 3715 O O   . LEU B 1 181 ? 124.916 102.843 120.455 1.00 89.10  ?  157  LEU R O   1 
ATOM 3716 C CB  . LEU B 1 181 ? 123.682 102.012 117.443 1.00 89.10  ?  157  LEU R CB  1 
ATOM 3717 C CG  . LEU B 1 181 ? 122.191 101.947 117.123 1.00 89.10  ?  157  LEU R CG  1 
ATOM 3718 C CD1 . LEU B 1 181 ? 121.428 101.437 118.330 1.00 89.10  ?  157  LEU R CD1 1 
ATOM 3719 C CD2 . LEU B 1 181 ? 121.663 103.302 116.691 1.00 89.10  ?  157  LEU R CD2 1 
ATOM 3720 N N   . ALA B 1 182 ? 126.428 102.554 118.802 1.00 90.58  ?  158  ALA R N   1 
ATOM 3721 C CA  . ALA B 1 182 ? 127.473 102.183 119.745 1.00 90.58  ?  158  ALA R CA  1 
ATOM 3722 C C   . ALA B 1 182 ? 127.744 103.313 120.724 1.00 90.58  ?  158  ALA R C   1 
ATOM 3723 O O   . ALA B 1 182 ? 127.863 103.078 121.930 1.00 90.58  ?  158  ALA R O   1 
ATOM 3724 C CB  . ALA B 1 182 ? 128.748 101.800 118.994 1.00 90.58  ?  158  ALA R CB  1 
ATOM 3725 N N   . LEU B 1 183 ? 127.819 104.548 120.230 1.00 93.74  ?  159  LEU R N   1 
ATOM 3726 C CA  . LEU B 1 183 ? 128.134 105.672 121.101 1.00 93.74  ?  159  LEU R CA  1 
ATOM 3727 C C   . LEU B 1 183 ? 127.034 105.911 122.125 1.00 93.74  ?  159  LEU R C   1 
ATOM 3728 O O   . LEU B 1 183 ? 127.324 106.142 123.303 1.00 93.74  ?  159  LEU R O   1 
ATOM 3729 C CB  . LEU B 1 183 ? 128.375 106.930 120.268 1.00 93.74  ?  159  LEU R CB  1 
ATOM 3730 C CG  . LEU B 1 183 ? 129.261 108.002 120.909 1.00 93.74  ?  159  LEU R CG  1 
ATOM 3731 C CD1 . LEU B 1 183 ? 130.564 107.397 121.406 1.00 93.74  ?  159  LEU R CD1 1 
ATOM 3732 C CD2 . LEU B 1 183 ? 129.531 109.133 119.930 1.00 93.74  ?  159  LEU R CD2 1 
ATOM 3733 N N   . VAL B 1 184 ? 125.767 105.861 121.706 1.00 83.52  ?  160  VAL R N   1 
ATOM 3734 C CA  . VAL B 1 184 ? 124.695 106.165 122.648 1.00 83.52  ?  160  VAL R CA  1 
ATOM 3735 C C   . VAL B 1 184 ? 124.611 105.092 123.725 1.00 83.52  ?  160  VAL R C   1 
ATOM 3736 O O   . VAL B 1 184 ? 124.505 105.404 124.919 1.00 83.52  ?  160  VAL R O   1 
ATOM 3737 C CB  . VAL B 1 184 ? 123.349 106.366 121.924 1.00 83.52  ?  160  VAL R CB  1 
ATOM 3738 C CG1 . VAL B 1 184 ? 123.421 107.570 120.995 1.00 83.52  ?  160  VAL R CG1 1 
ATOM 3739 C CG2 . VAL B 1 184 ? 122.922 105.124 121.168 1.00 83.52  ?  160  VAL R CG2 1 
ATOM 3740 N N   . TRP B 1 185 ? 124.699 103.816 123.342 1.00 74.71  ?  161  TRP R N   1 
ATOM 3741 C CA  . TRP B 1 185 ? 124.609 102.790 124.374 1.00 74.71  ?  161  TRP R CA  1 
ATOM 3742 C C   . TRP B 1 185 ? 125.864 102.744 125.239 1.00 74.71  ?  161  TRP R C   1 
ATOM 3743 O O   . TRP B 1 185 ? 125.777 102.442 126.433 1.00 74.71  ?  161  TRP R O   1 
ATOM 3744 C CB  . TRP B 1 185 ? 124.318 101.434 123.745 1.00 74.71  ?  161  TRP R CB  1 
ATOM 3745 C CG  . TRP B 1 185 ? 122.855 101.199 123.567 1.00 74.71  ?  161  TRP R CG  1 
ATOM 3746 C CD1 . TRP B 1 185 ? 122.139 101.356 122.423 1.00 74.71  ?  161  TRP R CD1 1 
ATOM 3747 C CD2 . TRP B 1 185 ? 121.927 100.761 124.564 1.00 74.71  ?  161  TRP R CD2 1 
ATOM 3748 N NE1 . TRP B 1 185 ? 120.822 101.044 122.641 1.00 74.71  ?  161  TRP R NE1 1 
ATOM 3749 C CE2 . TRP B 1 185 ? 120.666 100.674 123.949 1.00 74.71  ?  161  TRP R CE2 1 
ATOM 3750 C CE3 . TRP B 1 185 ? 122.042 100.429 125.916 1.00 74.71  ?  161  TRP R CE3 1 
ATOM 3751 C CZ2 . TRP B 1 185 ? 119.526 100.273 124.637 1.00 74.71  ?  161  TRP R CZ2 1 
ATOM 3752 C CZ3 . TRP B 1 185 ? 120.908 100.032 126.598 1.00 74.71  ?  161  TRP R CZ3 1 
ATOM 3753 C CH2 . TRP B 1 185 ? 119.667 99.957  125.957 1.00 74.71  ?  161  TRP R CH2 1 
ATOM 3754 N N   . GLY B 1 186 ? 127.032 103.069 124.679 1.00 89.60  ?  162  GLY R N   1 
ATOM 3755 C CA  . GLY B 1 186 ? 128.232 103.140 125.495 1.00 89.60  ?  162  GLY R CA  1 
ATOM 3756 C C   . GLY B 1 186 ? 128.190 104.277 126.496 1.00 89.60  ?  162  GLY R C   1 
ATOM 3757 O O   . GLY B 1 186 ? 128.632 104.127 127.637 1.00 89.60  ?  162  GLY R O   1 
ATOM 3758 N N   . GLY B 1 187 ? 127.674 105.434 126.081 1.00 89.68  ?  163  GLY R N   1 
ATOM 3759 C CA  . GLY B 1 187 ? 127.469 106.515 127.029 1.00 89.68  ?  163  GLY R CA  1 
ATOM 3760 C C   . GLY B 1 187 ? 126.464 106.146 128.100 1.00 89.68  ?  163  GLY R C   1 
ATOM 3761 O O   . GLY B 1 187 ? 126.612 106.525 129.265 1.00 89.68  ?  163  GLY R O   1 
ATOM 3762 N N   . ALA B 1 188 ? 125.426 105.399 127.720 1.00 86.03  ?  164  ALA R N   1 
ATOM 3763 C CA  . ALA B 1 188 ? 124.476 104.903 128.709 1.00 86.03  ?  164  ALA R CA  1 
ATOM 3764 C C   . ALA B 1 188 ? 125.166 103.992 129.715 1.00 86.03  ?  164  ALA R C   1 
ATOM 3765 O O   . ALA B 1 188 ? 124.890 104.051 130.918 1.00 86.03  ?  164  ALA R O   1 
ATOM 3766 C CB  . ALA B 1 188 ? 123.328 104.177 128.008 1.00 86.03  ?  164  ALA R CB  1 
ATOM 3767 N N   . LEU B 1 189 ? 126.069 103.134 129.235 1.00 89.18  ?  165  LEU R N   1 
ATOM 3768 C CA  . LEU B 1 189 ? 126.855 102.300 130.140 1.00 89.18  ?  165  LEU R CA  1 
ATOM 3769 C C   . LEU B 1 189 ? 127.732 103.140 131.058 1.00 89.18  ?  165  LEU R C   1 
ATOM 3770 O O   . LEU B 1 189 ? 127.820 102.864 132.259 1.00 89.18  ?  165  LEU R O   1 
ATOM 3771 C CB  . LEU B 1 189 ? 127.723 101.322 129.346 1.00 89.18  ?  165  LEU R CB  1 
ATOM 3772 C CG  . LEU B 1 189 ? 127.220 99.895  129.105 1.00 89.18  ?  165  LEU R CG  1 
ATOM 3773 C CD1 . LEU B 1 189 ? 127.083 99.139  130.422 1.00 89.18  ?  165  LEU R CD1 1 
ATOM 3774 C CD2 . LEU B 1 189 ? 125.919 99.868  128.315 1.00 89.18  ?  165  LEU R CD2 1 
ATOM 3775 N N   . GLY B 1 190 ? 128.383 104.167 130.511 1.00 94.47  ?  166  GLY R N   1 
ATOM 3776 C CA  . GLY B 1 190 ? 129.325 104.946 131.293 1.00 94.47  ?  166  GLY R CA  1 
ATOM 3777 C C   . GLY B 1 190 ? 128.686 105.862 132.312 1.00 94.47  ?  166  GLY R C   1 
ATOM 3778 O O   . GLY B 1 190 ? 129.291 106.150 133.349 1.00 94.47  ?  166  GLY R O   1 
ATOM 3779 N N   . LEU B 1 191 ? 127.473 106.340 132.041 1.00 93.43  ?  167  LEU R N   1 
ATOM 3780 C CA  . LEU B 1 191 ? 126.768 107.231 132.954 1.00 93.43  ?  167  LEU R CA  1 
ATOM 3781 C C   . LEU B 1 191 ? 125.580 106.558 133.627 1.00 93.43  ?  167  LEU R C   1 
ATOM 3782 O O   . LEU B 1 191 ? 124.791 107.235 134.294 1.00 93.43  ?  167  LEU R O   1 
ATOM 3783 C CB  . LEU B 1 191 ? 126.312 108.491 132.217 1.00 93.43  ?  167  LEU R CB  1 
ATOM 3784 C CG  . LEU B 1 191 ? 127.419 109.446 131.770 1.00 93.43  ?  167  LEU R CG  1 
ATOM 3785 C CD1 . LEU B 1 191 ? 126.855 110.834 131.513 1.00 93.43  ?  167  LEU R CD1 1 
ATOM 3786 C CD2 . LEU B 1 191 ? 128.533 109.501 132.802 1.00 93.43  ?  167  LEU R CD2 1 
ATOM 3787 N N   . GLY B 1 192 ? 125.436 105.246 133.474 1.00 95.08  ?  168  GLY R N   1 
ATOM 3788 C CA  . GLY B 1 192 ? 124.324 104.523 134.057 1.00 95.08  ?  168  GLY R CA  1 
ATOM 3789 C C   . GLY B 1 192 ? 124.727 103.580 135.171 1.00 95.08  ?  168  GLY R C   1 
ATOM 3790 O O   . GLY B 1 192 ? 124.883 103.992 136.324 1.00 95.08  ?  168  GLY R O   1 
ATOM 3791 N N   . LEU B 1 193 ? 124.877 102.298 134.834 1.00 92.20  ?  169  LEU R N   1 
ATOM 3792 C CA  . LEU B 1 193 ? 125.203 101.295 135.842 1.00 92.20  ?  169  LEU R CA  1 
ATOM 3793 C C   . LEU B 1 193 ? 126.558 101.563 136.485 1.00 92.20  ?  169  LEU R C   1 
ATOM 3794 O O   . LEU B 1 193 ? 126.718 101.396 137.699 1.00 92.20  ?  169  LEU R O   1 
ATOM 3795 C CB  . LEU B 1 193 ? 125.183 99.901  135.219 1.00 92.20  ?  169  LEU R CB  1 
ATOM 3796 C CG  . LEU B 1 193 ? 123.904 99.076  135.357 1.00 92.20  ?  169  LEU R CG  1 
ATOM 3797 C CD1 . LEU B 1 193 ? 123.865 98.367  136.703 1.00 92.20  ?  169  LEU R CD1 1 
ATOM 3798 C CD2 . LEU B 1 193 ? 122.677 99.941  135.167 1.00 92.20  ?  169  LEU R CD2 1 
ATOM 3799 N N   . LEU B 1 194 ? 127.550 101.957 135.687 1.00 95.36  ?  170  LEU R N   1 
ATOM 3800 C CA  . LEU B 1 194 ? 128.904 102.102 136.218 1.00 95.36  ?  170  LEU R CA  1 
ATOM 3801 C C   . LEU B 1 194 ? 128.996 103.146 137.324 1.00 95.36  ?  170  LEU R C   1 
ATOM 3802 O O   . LEU B 1 194 ? 129.625 102.859 138.357 1.00 95.36  ?  170  LEU R O   1 
ATOM 3803 C CB  . LEU B 1 194 ? 129.882 102.373 135.065 1.00 95.36  ?  170  LEU R CB  1 
ATOM 3804 C CG  . LEU B 1 194 ? 131.293 102.933 135.299 1.00 95.36  ?  170  LEU R CG  1 
ATOM 3805 C CD1 . LEU B 1 194 ? 132.192 102.505 134.152 1.00 95.36  ?  170  LEU R CD1 1 
ATOM 3806 C CD2 . LEU B 1 194 ? 131.323 104.451 135.417 1.00 95.36  ?  170  LEU R CD2 1 
ATOM 3807 N N   . PRO B 1 195 ? 128.421 104.348 137.199 1.00 91.49  ?  171  PRO R N   1 
ATOM 3808 C CA  . PRO B 1 195 ? 128.506 105.287 138.328 1.00 91.49  ?  171  PRO R CA  1 
ATOM 3809 C C   . PRO B 1 195 ? 127.614 104.907 139.495 1.00 91.49  ?  171  PRO R C   1 
ATOM 3810 O O   . PRO B 1 195 ? 127.916 105.289 140.631 1.00 91.49  ?  171  PRO R O   1 
ATOM 3811 C CB  . PRO B 1 195 ? 128.080 106.636 137.731 1.00 91.49  ?  171  PRO R CB  1 
ATOM 3812 C CG  . PRO B 1 195 ? 127.675 106.392 136.354 1.00 91.49  ?  171  PRO R CG  1 
ATOM 3813 C CD  . PRO B 1 195 ? 127.898 104.978 135.975 1.00 91.49  ?  171  PRO R CD  1 
ATOM 3814 N N   . VAL B 1 196 ? 126.521 104.183 139.260 1.00 96.07  ?  172  VAL R N   1 
ATOM 3815 C CA  . VAL B 1 196 ? 125.566 103.937 140.336 1.00 96.07  ?  172  VAL R CA  1 
ATOM 3816 C C   . VAL B 1 196 ? 126.031 102.797 141.233 1.00 96.07  ?  172  VAL R C   1 
ATOM 3817 O O   . VAL B 1 196 ? 125.765 102.801 142.440 1.00 96.07  ?  172  VAL R O   1 
ATOM 3818 C CB  . VAL B 1 196 ? 124.158 103.681 139.765 1.00 96.07  ?  172  VAL R CB  1 
ATOM 3819 C CG1 . VAL B 1 196 ? 124.074 102.316 139.118 1.00 96.07  ?  172  VAL R CG1 1 
ATOM 3820 C CG2 . VAL B 1 196 ? 123.110 103.819 140.857 1.00 96.07  ?  172  VAL R CG2 1 
ATOM 3821 N N   . LEU B 1 197 ? 126.727 101.807 140.680 1.00 97.77  ?  173  LEU R N   1 
ATOM 3822 C CA  . LEU B 1 197 ? 127.248 100.715 141.500 1.00 97.77  ?  173  LEU R CA  1 
ATOM 3823 C C   . LEU B 1 197 ? 128.622 101.065 142.057 1.00 97.77  ?  173  LEU R C   1 
ATOM 3824 O O   . LEU B 1 197 ? 129.562 100.273 142.040 1.00 97.77  ?  173  LEU R O   1 
ATOM 3825 C CB  . LEU B 1 197 ? 127.292 99.428  140.687 1.00 97.77  ?  173  LEU R CB  1 
ATOM 3826 C CG  . LEU B 1 197 ? 126.006 98.600  140.672 1.00 97.77  ?  173  LEU R CG  1 
ATOM 3827 C CD1 . LEU B 1 197 ? 126.257 97.225  140.072 1.00 97.77  ?  173  LEU R CD1 1 
ATOM 3828 C CD2 . LEU B 1 197 ? 125.426 98.480  142.072 1.00 97.77  ?  173  LEU R CD2 1 
ATOM 3829 N N   . ALA B 1 198 ? 128.710 102.284 142.575 1.00 94.77  ?  174  ALA R N   1 
ATOM 3830 C CA  . ALA B 1 198 ? 129.874 102.869 143.224 1.00 94.77  ?  174  ALA R CA  1 
ATOM 3831 C C   . ALA B 1 198 ? 129.448 104.271 143.631 1.00 94.77  ?  174  ALA R C   1 
ATOM 3832 O O   . ALA B 1 198 ? 128.386 104.750 143.224 1.00 94.77  ?  174  ALA R O   1 
ATOM 3833 C CB  . ALA B 1 198 ? 131.104 102.918 142.318 1.00 94.77  ?  174  ALA R CB  1 
ATOM 3834 N N   . TRP B 1 199 ? 130.277 104.920 144.448 1.00 97.81  ?  175  TRP R N   1 
ATOM 3835 C CA  . TRP B 1 199 ? 130.136 106.353 144.698 1.00 97.81  ?  175  TRP R CA  1 
ATOM 3836 C C   . TRP B 1 199 ? 128.728 106.695 145.187 1.00 97.81  ?  175  TRP R C   1 
ATOM 3837 O O   . TRP B 1 199 ? 128.156 107.729 144.837 1.00 97.81  ?  175  TRP R O   1 
ATOM 3838 C CB  . TRP B 1 199 ? 130.491 107.131 143.430 1.00 97.81  ?  175  TRP R CB  1 
ATOM 3839 C CG  . TRP B 1 199 ? 130.773 108.583 143.615 1.00 97.81  ?  175  TRP R CG  1 
ATOM 3840 C CD1 . TRP B 1 199 ? 130.911 109.254 144.793 1.00 97.81  ?  175  TRP R CD1 1 
ATOM 3841 C CD2 . TRP B 1 199 ? 130.967 109.548 142.576 1.00 97.81  ?  175  TRP R CD2 1 
ATOM 3842 N NE1 . TRP B 1 199 ? 131.173 110.582 144.551 1.00 97.81  ?  175  TRP R NE1 1 
ATOM 3843 C CE2 . TRP B 1 199 ? 131.213 110.787 143.196 1.00 97.81  ?  175  TRP R CE2 1 
ATOM 3844 C CE3 . TRP B 1 199 ? 130.953 109.485 141.179 1.00 97.81  ?  175  TRP R CE3 1 
ATOM 3845 C CZ2 . TRP B 1 199 ? 131.444 111.952 142.469 1.00 97.81  ?  175  TRP R CZ2 1 
ATOM 3846 C CZ3 . TRP B 1 199 ? 131.182 110.642 140.460 1.00 97.81  ?  175  TRP R CZ3 1 
ATOM 3847 C CH2 . TRP B 1 199 ? 131.424 111.858 141.105 1.00 97.81  ?  175  TRP R CH2 1 
ATOM 3848 N N   . ASN B 1 200 ? 128.161 105.812 146.005 1.00 98.27  ?  176  ASN R N   1 
ATOM 3849 C CA  . ASN B 1 200 ? 126.756 105.865 146.373 1.00 98.27  ?  176  ASN R CA  1 
ATOM 3850 C C   . ASN B 1 200 ? 126.580 106.487 147.758 1.00 98.27  ?  176  ASN R C   1 
ATOM 3851 O O   . ASN B 1 200 ? 127.524 107.004 148.360 1.00 98.27  ?  176  ASN R O   1 
ATOM 3852 C CB  . ASN B 1 200 ? 126.153 104.463 146.307 1.00 98.27  ?  176  ASN R CB  1 
ATOM 3853 C CG  . ASN B 1 200 ? 127.108 103.395 146.802 1.00 98.27  ?  176  ASN R CG  1 
ATOM 3854 O OD1 . ASN B 1 200 ? 128.253 103.315 146.358 1.00 98.27  ?  176  ASN R OD1 1 
ATOM 3855 N ND2 . ASN B 1 200 ? 126.640 102.567 147.729 1.00 98.27  ?  176  ASN R ND2 1 
ATOM 3856 N N   . CYS B 1 201 ? 125.347 106.441 148.270 1.00 99.85  ?  177  CYS R N   1 
ATOM 3857 C CA  . CYS B 1 201 ? 124.999 107.055 149.544 1.00 99.85  ?  177  CYS R CA  1 
ATOM 3858 C C   . CYS B 1 201 ? 124.875 106.059 150.690 1.00 99.85  ?  177  CYS R C   1 
ATOM 3859 O O   . CYS B 1 201 ? 124.991 106.463 151.852 1.00 99.85  ?  177  CYS R O   1 
ATOM 3860 C CB  . CYS B 1 201 ? 123.681 107.835 149.411 1.00 99.85  ?  177  CYS R CB  1 
ATOM 3861 S SG  . CYS B 1 201 ? 123.047 108.578 150.947 1.00 99.85  ?  177  CYS R SG  1 
ATOM 3862 N N   . LEU B 1 202 ? 124.680 104.771 150.405 1.00 98.12  ?  178  LEU R N   1 
ATOM 3863 C CA  . LEU B 1 202 ? 124.508 103.766 151.455 1.00 98.12  ?  178  LEU R CA  1 
ATOM 3864 C C   . LEU B 1 202 ? 125.860 103.417 152.084 1.00 98.12  ?  178  LEU R C   1 
ATOM 3865 O O   . LEU B 1 202 ? 126.285 102.264 152.147 1.00 98.12  ?  178  LEU R O   1 
ATOM 3866 C CB  . LEU B 1 202 ? 123.822 102.528 150.894 1.00 98.12  ?  178  LEU R CB  1 
ATOM 3867 C CG  . LEU B 1 202 ? 122.311 102.415 151.107 1.00 98.12  ?  178  LEU R CG  1 
ATOM 3868 C CD1 . LEU B 1 202 ? 121.997 102.041 152.548 1.00 98.12  ?  178  LEU R CD1 1 
ATOM 3869 C CD2 . LEU B 1 202 ? 121.609 103.703 150.717 1.00 98.12  ?  178  LEU R CD2 1 
ATOM 3870 N N   . ASP B 1 203 ? 126.532 104.458 152.559 1.00 98.19  ?  179  ASP R N   1 
ATOM 3871 C CA  . ASP B 1 203 ? 127.880 104.381 153.101 1.00 98.19  ?  179  ASP R CA  1 
ATOM 3872 C C   . ASP B 1 203 ? 128.075 105.604 153.992 1.00 98.19  ?  179  ASP R C   1 
ATOM 3873 O O   . ASP B 1 203 ? 127.098 106.216 154.438 1.00 98.19  ?  179  ASP R O   1 
ATOM 3874 C CB  . ASP B 1 203 ? 128.919 104.279 151.972 1.00 98.19  ?  179  ASP R CB  1 
ATOM 3875 C CG  . ASP B 1 203 ? 128.686 105.291 150.871 1.00 98.19  ?  179  ASP R CG  1 
ATOM 3876 O OD1 . ASP B 1 203 ? 127.825 106.175 151.048 1.00 98.19  ?  179  ASP R OD1 1 
ATOM 3877 O OD2 . ASP B 1 203 ? 129.364 105.201 149.826 1.00 98.19  -1 179  ASP R OD2 1 
ATOM 3878 N N   . GLY B 1 204 ? 129.331 105.941 154.277 1.00 91.18  ?  180  GLY R N   1 
ATOM 3879 C CA  . GLY B 1 204 ? 129.642 107.147 155.022 1.00 91.18  ?  180  GLY R CA  1 
ATOM 3880 C C   . GLY B 1 204 ? 129.057 108.402 154.405 1.00 91.18  ?  180  GLY R C   1 
ATOM 3881 O O   . GLY B 1 204 ? 128.426 108.344 153.348 1.00 91.18  ?  180  GLY R O   1 
ATOM 3882 N N   . LEU B 1 205 ? 129.253 109.543 155.058 1.00 94.86  ?  181  LEU R N   1 
ATOM 3883 C CA  . LEU B 1 205 ? 128.598 110.780 154.648 1.00 94.86  ?  181  LEU R CA  1 
ATOM 3884 C C   . LEU B 1 205 ? 128.961 111.162 153.219 1.00 94.86  ?  181  LEU R C   1 
ATOM 3885 O O   . LEU B 1 205 ? 130.118 111.474 152.923 1.00 94.86  ?  181  LEU R O   1 
ATOM 3886 C CB  . LEU B 1 205 ? 128.977 111.910 155.609 1.00 94.86  ?  181  LEU R CB  1 
ATOM 3887 C CG  . LEU B 1 205 ? 128.507 111.811 157.064 1.00 94.86  ?  181  LEU R CG  1 
ATOM 3888 C CD1 . LEU B 1 205 ? 127.128 111.171 157.155 1.00 94.86  ?  181  LEU R CD1 1 
ATOM 3889 C CD2 . LEU B 1 205 ? 129.516 111.061 157.928 1.00 94.86  ?  181  LEU R CD2 1 
ATOM 3890 N N   . THR B 1 206 ? 127.961 111.131 152.333 1.00 95.52  ?  182  THR R N   1 
ATOM 3891 C CA  . THR B 1 206 ? 128.103 111.614 150.965 1.00 95.52  ?  182  THR R CA  1 
ATOM 3892 C C   . THR B 1 206 ? 127.121 112.714 150.596 1.00 95.52  ?  182  THR R C   1 
ATOM 3893 O O   . THR B 1 206 ? 127.234 113.269 149.497 1.00 95.52  ?  182  THR R O   1 
ATOM 3894 C CB  . THR B 1 206 ? 127.940 110.467 149.953 1.00 95.52  ?  182  THR R CB  1 
ATOM 3895 O OG1 . THR B 1 206 ? 126.546 110.198 149.750 1.00 95.52  ?  182  THR R OG1 1 
ATOM 3896 C CG2 . THR B 1 206 ? 128.648 109.215 150.421 1.00 95.52  ?  182  THR R CG2 1 
ATOM 3897 N N   . THR B 1 207 ? 126.173 113.048 151.473 1.00 92.70  ?  183  THR R N   1 
ATOM 3898 C CA  . THR B 1 207 ? 125.150 114.055 151.195 1.00 92.70  ?  183  THR R CA  1 
ATOM 3899 C C   . THR B 1 207 ? 124.413 113.734 149.900 1.00 92.70  ?  183  THR R C   1 
ATOM 3900 O O   . THR B 1 207 ? 124.357 114.540 148.970 1.00 92.70  ?  183  THR R O   1 
ATOM 3901 C CB  . THR B 1 207 ? 125.750 115.460 151.147 1.00 92.70  ?  183  THR R CB  1 
ATOM 3902 O OG1 . THR B 1 207 ? 126.413 115.654 149.893 1.00 92.70  ?  183  THR R OG1 1 
ATOM 3903 C CG2 . THR B 1 207 ? 126.744 115.661 152.283 1.00 92.70  ?  183  THR R CG2 1 
ATOM 3904 N N   . CYS B 1 208 ? 123.850 112.531 149.843 1.00 93.72  ?  184  CYS R N   1 
ATOM 3905 C CA  . CYS B 1 208 ? 123.137 112.105 148.649 1.00 93.72  ?  184  CYS R CA  1 
ATOM 3906 C C   . CYS B 1 208 ? 121.926 112.994 148.403 1.00 93.72  ?  184  CYS R C   1 
ATOM 3907 O O   . CYS B 1 208 ? 121.248 113.426 149.339 1.00 93.72  ?  184  CYS R O   1 
ATOM 3908 C CB  . CYS B 1 208 ? 122.718 110.639 148.770 1.00 93.72  ?  184  CYS R CB  1 
ATOM 3909 S SG  . CYS B 1 208 ? 121.957 110.181 150.337 1.00 93.72  ?  184  CYS R SG  1 
ATOM 3910 N N   . GLY B 1 209 ? 121.657 113.259 147.128 1.00 83.45  ?  185  GLY R N   1 
ATOM 3911 C CA  . GLY B 1 209 ? 120.703 114.274 146.734 1.00 83.45  ?  185  GLY R CA  1 
ATOM 3912 C C   . GLY B 1 209 ? 119.244 113.884 146.825 1.00 83.45  ?  185  GLY R C   1 
ATOM 3913 O O   . GLY B 1 209 ? 118.822 113.220 147.775 1.00 83.45  ?  185  GLY R O   1 
ATOM 3914 N N   . VAL B 1 210 ? 118.467 114.301 145.826 1.00 74.03  ?  186  VAL R N   1 
ATOM 3915 C CA  . VAL B 1 210 ? 117.013 114.224 145.920 1.00 74.03  ?  186  VAL R CA  1 
ATOM 3916 C C   . VAL B 1 210 ? 116.539 112.776 145.896 1.00 74.03  ?  186  VAL R C   1 
ATOM 3917 O O   . VAL B 1 210 ? 115.701 112.369 146.708 1.00 74.03  ?  186  VAL R O   1 
ATOM 3918 C CB  . VAL B 1 210 ? 116.369 115.049 144.795 1.00 74.03  ?  186  VAL R CB  1 
ATOM 3919 C CG1 . VAL B 1 210 ? 114.906 115.295 145.096 1.00 74.03  ?  186  VAL R CG1 1 
ATOM 3920 C CG2 . VAL B 1 210 ? 117.110 116.360 144.621 1.00 74.03  ?  186  VAL R CG2 1 
ATOM 3921 N N   . VAL B 1 211 ? 117.055 111.981 144.969 1.00 73.40  ?  187  VAL R N   1 
ATOM 3922 C CA  . VAL B 1 211 ? 116.614 110.602 144.800 1.00 73.40  ?  187  VAL R CA  1 
ATOM 3923 C C   . VAL B 1 211 ? 117.491 109.694 145.649 1.00 73.40  ?  187  VAL R C   1 
ATOM 3924 O O   . VAL B 1 211 ? 118.724 109.766 145.586 1.00 73.40  ?  187  VAL R O   1 
ATOM 3925 C CB  . VAL B 1 211 ? 116.656 110.186 143.322 1.00 73.40  ?  187  VAL R CB  1 
ATOM 3926 C CG1 . VAL B 1 211 ? 116.187 108.751 143.164 1.00 73.40  ?  187  VAL R CG1 1 
ATOM 3927 C CG2 . VAL B 1 211 ? 115.803 111.125 142.485 1.00 73.40  ?  187  VAL R CG2 1 
ATOM 3928 N N   . TYR B 1 212 ? 116.855 108.837 146.446 1.00 70.80  ?  188  TYR R N   1 
ATOM 3929 C CA  . TYR B 1 212 ? 117.560 107.979 147.383 1.00 70.80  ?  188  TYR R CA  1 
ATOM 3930 C C   . TYR B 1 212 ? 117.746 106.599 146.780 1.00 70.80  ?  188  TYR R C   1 
ATOM 3931 O O   . TYR B 1 212 ? 116.745 105.947 146.445 1.00 70.80  ?  188  TYR R O   1 
ATOM 3932 C CB  . TYR B 1 212 ? 116.782 107.877 148.688 1.00 70.80  ?  188  TYR R CB  1 
ATOM 3933 C CG  . TYR B 1 212 ? 117.465 107.067 149.758 1.00 70.80  ?  188  TYR R CG  1 
ATOM 3934 C CD1 . TYR B 1 212 ? 118.811 107.239 150.030 1.00 70.80  ?  188  TYR R CD1 1 
ATOM 3935 C CD2 . TYR B 1 212 ? 116.763 106.129 150.495 1.00 70.80  ?  188  TYR R CD2 1 
ATOM 3936 C CE1 . TYR B 1 212 ? 119.439 106.502 151.009 1.00 70.80  ?  188  TYR R CE1 1 
ATOM 3937 C CE2 . TYR B 1 212 ? 117.380 105.386 151.474 1.00 70.80  ?  188  TYR R CE2 1 
ATOM 3938 C CZ  . TYR B 1 212 ? 118.719 105.575 151.727 1.00 70.80  ?  188  TYR R CZ  1 
ATOM 3939 O OH  . TYR B 1 212 ? 119.338 104.834 152.707 1.00 70.80  ?  188  TYR R OH  1 
ATOM 3940 N N   . PRO B 1 213 ? 118.977 106.104 146.625 1.00 70.18  ?  189  PRO R N   1 
ATOM 3941 C CA  . PRO B 1 213 ? 120.254 106.765 146.880 1.00 70.18  ?  189  PRO R CA  1 
ATOM 3942 C C   . PRO B 1 213 ? 120.935 107.260 145.613 1.00 70.18  ?  189  PRO R C   1 
ATOM 3943 O O   . PRO B 1 213 ? 121.214 106.482 144.712 1.00 70.18  ?  189  PRO R O   1 
ATOM 3944 C CB  . PRO B 1 213 ? 121.065 105.658 147.555 1.00 70.18  ?  189  PRO R CB  1 
ATOM 3945 C CG  . PRO B 1 213 ? 120.537 104.371 146.941 1.00 70.18  ?  189  PRO R CG  1 
ATOM 3946 C CD  . PRO B 1 213 ? 119.171 104.673 146.351 1.00 70.18  ?  189  PRO R CD  1 
ATOM 3947 N N   . LEU B 1 214 ? 121.230 108.553 145.530 1.00 74.91  ?  190  LEU R N   1 
ATOM 3948 C CA  . LEU B 1 214 ? 121.994 109.116 144.426 1.00 74.91  ?  190  LEU R CA  1 
ATOM 3949 C C   . LEU B 1 214 ? 122.819 110.273 144.960 1.00 74.91  ?  190  LEU R C   1 
ATOM 3950 O O   . LEU B 1 214 ? 122.288 111.148 145.646 1.00 74.91  ?  190  LEU R O   1 
ATOM 3951 C CB  . LEU B 1 214 ? 121.081 109.597 143.291 1.00 74.91  ?  190  LEU R CB  1 
ATOM 3952 C CG  . LEU B 1 214 ? 120.385 108.590 142.372 1.00 74.91  ?  190  LEU R CG  1 
ATOM 3953 C CD1 . LEU B 1 214 ? 119.726 109.318 141.215 1.00 74.91  ?  190  LEU R CD1 1 
ATOM 3954 C CD2 . LEU B 1 214 ? 121.379 107.577 141.834 1.00 74.91  ?  190  LEU R CD2 1 
ATOM 3955 N N   . SER B 1 215 ? 124.107 110.279 144.641 1.00 83.52  ?  191  SER R N   1 
ATOM 3956 C CA  . SER B 1 215 ? 124.965 111.366 145.076 1.00 83.52  ?  191  SER R CA  1 
ATOM 3957 C C   . SER B 1 215 ? 124.608 112.655 144.342 1.00 83.52  ?  191  SER R C   1 
ATOM 3958 O O   . SER B 1 215 ? 124.035 112.645 143.249 1.00 83.52  ?  191  SER R O   1 
ATOM 3959 C CB  . SER B 1 215 ? 126.434 111.018 144.842 1.00 83.52  ?  191  SER R CB  1 
ATOM 3960 O OG  . SER B 1 215 ? 127.270 112.132 145.106 1.00 83.52  ?  191  SER R OG  1 
ATOM 3961 N N   . LYS B 1 216 ? 124.947 113.781 144.971 1.00 80.08  ?  192  LYS R N   1 
ATOM 3962 C CA  . LYS B 1 216 ? 124.676 115.079 144.363 1.00 80.08  ?  192  LYS R CA  1 
ATOM 3963 C C   . LYS B 1 216 ? 125.452 115.253 143.066 1.00 80.08  ?  192  LYS R C   1 
ATOM 3964 O O   . LYS B 1 216 ? 124.913 115.746 142.066 1.00 80.08  ?  192  LYS R O   1 
ATOM 3965 C CB  . LYS B 1 216 ? 125.022 116.194 145.348 1.00 80.08  ?  192  LYS R CB  1 
ATOM 3966 C CG  . LYS B 1 216 ? 124.741 117.594 144.838 1.00 80.08  ?  192  LYS R CG  1 
ATOM 3967 C CD  . LYS B 1 216 ? 123.247 117.855 144.748 1.00 80.08  ?  192  LYS R CD  1 
ATOM 3968 C CE  . LYS B 1 216 ? 122.929 119.324 144.963 1.00 80.08  ?  192  LYS R CE  1 
ATOM 3969 N NZ  . LYS B 1 216 ? 123.056 119.712 146.391 1.00 80.08  1  192  LYS R NZ  1 
ATOM 3970 N N   . ASN B 1 217 ? 126.720 114.842 143.063 1.00 83.44  ?  193  ASN R N   1 
ATOM 3971 C CA  . ASN B 1 217 ? 127.576 115.067 141.904 1.00 83.44  ?  193  ASN R CA  1 
ATOM 3972 C C   . ASN B 1 217 ? 127.079 114.302 140.685 1.00 83.44  ?  193  ASN R C   1 
ATOM 3973 O O   . ASN B 1 217 ? 127.095 114.824 139.562 1.00 83.44  ?  193  ASN R O   1 
ATOM 3974 C CB  . ASN B 1 217 ? 129.008 114.676 142.255 1.00 83.44  ?  193  ASN R CB  1 
ATOM 3975 C CG  . ASN B 1 217 ? 129.336 114.953 143.709 1.00 83.44  ?  193  ASN R CG  1 
ATOM 3976 O OD1 . ASN B 1 217 ? 128.914 115.964 144.267 1.00 83.44  ?  193  ASN R OD1 1 
ATOM 3977 N ND2 . ASN B 1 217 ? 130.086 114.053 144.332 1.00 83.44  ?  193  ASN R ND2 1 
ATOM 3978 N N   . HIS B 1 218 ? 126.637 113.061 140.885 1.00 81.95  ?  194  HIS R N   1 
ATOM 3979 C CA  . HIS B 1 218 ? 126.121 112.267 139.777 1.00 81.95  ?  194  HIS R CA  1 
ATOM 3980 C C   . HIS B 1 218 ? 124.904 112.929 139.146 1.00 81.95  ?  194  HIS R C   1 
ATOM 3981 O O   . HIS B 1 218 ? 124.796 113.018 137.914 1.00 81.95  ?  194  HIS R O   1 
ATOM 3982 C CB  . HIS B 1 218 ? 125.777 110.865 140.274 1.00 81.95  ?  194  HIS R CB  1 
ATOM 3983 C CG  . HIS B 1 218 ? 125.498 109.885 139.182 1.00 81.95  ?  194  HIS R CG  1 
ATOM 3984 N ND1 . HIS B 1 218 ? 125.968 110.048 137.897 1.00 81.95  ?  194  HIS R ND1 1 
ATOM 3985 C CD2 . HIS B 1 218 ? 124.800 108.726 139.184 1.00 81.95  ?  194  HIS R CD2 1 
ATOM 3986 C CE1 . HIS B 1 218 ? 125.568 109.033 137.153 1.00 81.95  ?  194  HIS R CE1 1 
ATOM 3987 N NE2 . HIS B 1 218 ? 124.858 108.216 137.910 1.00 81.95  ?  194  HIS R NE2 1 
ATOM 3988 N N   . LEU B 1 219 ? 123.982 113.413 139.979 1.00 75.07  ?  195  LEU R N   1 
ATOM 3989 C CA  . LEU B 1 219 ? 122.790 114.073 139.464 1.00 75.07  ?  195  LEU R CA  1 
ATOM 3990 C C   . LEU B 1 219 ? 123.143 115.360 138.729 1.00 75.07  ?  195  LEU R C   1 
ATOM 3991 O O   . LEU B 1 219 ? 122.549 115.668 137.688 1.00 75.07  ?  195  LEU R O   1 
ATOM 3992 C CB  . LEU B 1 219 ? 121.817 114.347 140.606 1.00 75.07  ?  195  LEU R CB  1 
ATOM 3993 C CG  . LEU B 1 219 ? 120.763 113.269 140.841 1.00 75.07  ?  195  LEU R CG  1 
ATOM 3994 C CD1 . LEU B 1 219 ? 119.702 113.766 141.805 1.00 75.07  ?  195  LEU R CD1 1 
ATOM 3995 C CD2 . LEU B 1 219 ? 120.136 112.847 139.530 1.00 75.07  ?  195  LEU R CD2 1 
ATOM 3996 N N   . VAL B 1 220 ? 124.110 116.121 139.248 1.00 75.16  ?  196  VAL R N   1 
ATOM 3997 C CA  . VAL B 1 220 ? 124.517 117.347 138.566 1.00 75.16  ?  196  VAL R CA  1 
ATOM 3998 C C   . VAL B 1 220 ? 125.108 117.029 137.197 1.00 75.16  ?  196  VAL R C   1 
ATOM 3999 O O   . VAL B 1 220 ? 124.822 117.715 136.204 1.00 75.16  ?  196  VAL R O   1 
ATOM 4000 C CB  . VAL B 1 220 ? 125.503 118.145 139.435 1.00 75.16  ?  196  VAL R CB  1 
ATOM 4001 C CG1 . VAL B 1 220 ? 126.101 119.283 138.631 1.00 75.16  ?  196  VAL R CG1 1 
ATOM 4002 C CG2 . VAL B 1 220 ? 124.801 118.678 140.670 1.00 75.16  ?  196  VAL R CG2 1 
ATOM 4003 N N   . VAL B 1 221 ? 125.941 115.990 137.122 1.00 68.84  ?  197  VAL R N   1 
ATOM 4004 C CA  . VAL B 1 221 ? 126.531 115.607 135.841 1.00 68.84  ?  197  VAL R CA  1 
ATOM 4005 C C   . VAL B 1 221 ? 125.443 115.199 134.856 1.00 68.84  ?  197  VAL R C   1 
ATOM 4006 O O   . VAL B 1 221 ? 125.468 115.586 133.675 1.00 68.84  ?  197  VAL R O   1 
ATOM 4007 C CB  . VAL B 1 221 ? 127.563 114.485 136.045 1.00 68.84  ?  197  VAL R CB  1 
ATOM 4008 C CG1 . VAL B 1 221 ? 127.915 113.838 134.718 1.00 68.84  ?  197  VAL R CG1 1 
ATOM 4009 C CG2 . VAL B 1 221 ? 128.807 115.034 136.719 1.00 68.84  ?  197  VAL R CG2 1 
ATOM 4010 N N   . LEU B 1 222 ? 124.465 114.422 135.325 1.00 68.44  ?  198  LEU R N   1 
ATOM 4011 C CA  . LEU B 1 222 ? 123.363 114.026 134.456 1.00 68.44  ?  198  LEU R CA  1 
ATOM 4012 C C   . LEU B 1 222 ? 122.595 115.240 133.944 1.00 68.44  ?  198  LEU R C   1 
ATOM 4013 O O   . LEU B 1 222 ? 122.238 115.307 132.760 1.00 68.44  ?  198  LEU R O   1 
ATOM 4014 C CB  . LEU B 1 222 ? 122.432 113.074 135.200 1.00 68.44  ?  198  LEU R CB  1 
ATOM 4015 C CG  . LEU B 1 222 ? 122.464 111.620 134.733 1.00 68.44  ?  198  LEU R CG  1 
ATOM 4016 C CD1 . LEU B 1 222 ? 123.879 111.076 134.786 1.00 68.44  ?  198  LEU R CD1 1 
ATOM 4017 C CD2 . LEU B 1 222 ? 121.528 110.770 135.573 1.00 68.44  ?  198  LEU R CD2 1 
ATOM 4018 N N   . ALA B 1 223 ? 122.336 116.215 134.819 1.00 68.16  ?  199  ALA R N   1 
ATOM 4019 C CA  . ALA B 1 223 ? 121.613 117.412 134.401 1.00 68.16  ?  199  ALA R CA  1 
ATOM 4020 C C   . ALA B 1 223 ? 122.395 118.204 133.358 1.00 68.16  ?  199  ALA R C   1 
ATOM 4021 O O   . ALA B 1 223 ? 121.814 118.727 132.395 1.00 68.16  ?  199  ALA R O   1 
ATOM 4022 C CB  . ALA B 1 223 ? 121.301 118.285 135.613 1.00 68.16  ?  199  ALA R CB  1 
ATOM 4023 N N   . ILE B 1 224 ? 123.712 118.315 133.538 1.00 62.74  ?  200  ILE R N   1 
ATOM 4024 C CA  . ILE B 1 224 ? 124.534 119.040 132.572 1.00 62.74  ?  200  ILE R CA  1 
ATOM 4025 C C   . ILE B 1 224 ? 124.466 118.366 131.207 1.00 62.74  ?  200  ILE R C   1 
ATOM 4026 O O   . ILE B 1 224 ? 124.299 119.025 130.166 1.00 62.74  ?  200  ILE R O   1 
ATOM 4027 C CB  . ILE B 1 224 ? 125.983 119.146 133.076 1.00 62.74  ?  200  ILE R CB  1 
ATOM 4028 C CG1 . ILE B 1 224 ? 126.049 120.041 134.312 1.00 62.74  ?  200  ILE R CG1 1 
ATOM 4029 C CG2 . ILE B 1 224 ? 126.889 119.687 131.988 1.00 62.74  ?  200  ILE R CG2 1 
ATOM 4030 C CD1 . ILE B 1 224 ? 127.437 120.174 134.892 1.00 62.74  ?  200  ILE R CD1 1 
ATOM 4031 N N   . ALA B 1 225 ? 124.588 117.037 131.192 1.00 62.96  ?  201  ALA R N   1 
ATOM 4032 C CA  . ALA B 1 225 ? 124.485 116.314 129.929 1.00 62.96  ?  201  ALA R CA  1 
ATOM 4033 C C   . ALA B 1 225 ? 123.124 116.536 129.284 1.00 62.96  ?  201  ALA R C   1 
ATOM 4034 O O   . ALA B 1 225 ? 123.027 116.727 128.061 1.00 62.96  ?  201  ALA R O   1 
ATOM 4035 C CB  . ALA B 1 225 ? 124.739 114.824 130.153 1.00 62.96  ?  201  ALA R CB  1 
ATOM 4036 N N   . PHE B 1 226 ? 122.061 116.529 130.091 1.00 62.95  ?  202  PHE R N   1 
ATOM 4037 C CA  . PHE B 1 226 ? 120.725 116.724 129.542 1.00 62.95  ?  202  PHE R CA  1 
ATOM 4038 C C   . PHE B 1 226 ? 120.583 118.096 128.902 1.00 62.95  ?  202  PHE R C   1 
ATOM 4039 O O   . PHE B 1 226 ? 119.964 118.232 127.841 1.00 62.95  ?  202  PHE R O   1 
ATOM 4040 C CB  . PHE B 1 226 ? 119.668 116.542 130.622 1.00 62.95  ?  202  PHE R CB  1 
ATOM 4041 C CG  . PHE B 1 226 ? 118.346 117.145 130.268 1.00 62.95  ?  202  PHE R CG  1 
ATOM 4042 C CD1 . PHE B 1 226 ? 117.543 116.563 129.311 1.00 62.95  ?  202  PHE R CD1 1 
ATOM 4043 C CD2 . PHE B 1 226 ? 117.908 118.299 130.885 1.00 62.95  ?  202  PHE R CD2 1 
ATOM 4044 C CE1 . PHE B 1 226 ? 116.329 117.112 128.980 1.00 62.95  ?  202  PHE R CE1 1 
ATOM 4045 C CE2 . PHE B 1 226 ? 116.692 118.853 130.555 1.00 62.95  ?  202  PHE R CE2 1 
ATOM 4046 C CZ  . PHE B 1 226 ? 115.902 118.255 129.601 1.00 62.95  ?  202  PHE R CZ  1 
ATOM 4047 N N   . PHE B 1 227 ? 121.136 119.131 129.534 1.00 58.19  ?  203  PHE R N   1 
ATOM 4048 C CA  . PHE B 1 227 ? 120.997 120.469 128.965 1.00 58.19  ?  203  PHE R CA  1 
ATOM 4049 C C   . PHE B 1 227 ? 121.801 120.618 127.677 1.00 58.19  ?  203  PHE R C   1 
ATOM 4050 O O   . PHE B 1 227 ? 121.346 121.273 126.726 1.00 58.19  ?  203  PHE R O   1 
ATOM 4051 C CB  . PHE B 1 227 ? 121.394 121.523 129.991 1.00 58.19  ?  203  PHE R CB  1 
ATOM 4052 C CG  . PHE B 1 227 ? 120.298 121.848 130.955 1.00 58.19  ?  203  PHE R CG  1 
ATOM 4053 C CD1 . PHE B 1 227 ? 119.055 122.226 130.496 1.00 58.19  ?  203  PHE R CD1 1 
ATOM 4054 C CD2 . PHE B 1 227 ? 120.501 121.756 132.316 1.00 58.19  ?  203  PHE R CD2 1 
ATOM 4055 C CE1 . PHE B 1 227 ? 118.041 122.519 131.372 1.00 58.19  ?  203  PHE R CE1 1 
ATOM 4056 C CE2 . PHE B 1 227 ? 119.486 122.044 133.196 1.00 58.19  ?  203  PHE R CE2 1 
ATOM 4057 C CZ  . PHE B 1 227 ? 118.256 122.429 132.722 1.00 58.19  ?  203  PHE R CZ  1 
ATOM 4058 N N   . MET B 1 228 ? 122.985 120.004 127.612 1.00 63.70  ?  204  MET R N   1 
ATOM 4059 C CA  . MET B 1 228 ? 123.723 120.016 126.351 1.00 63.70  ?  204  MET R CA  1 
ATOM 4060 C C   . MET B 1 228 ? 122.923 119.337 125.243 1.00 63.70  ?  204  MET R C   1 
ATOM 4061 O O   . MET B 1 228 ? 122.844 119.842 124.110 1.00 63.70  ?  204  MET R O   1 
ATOM 4062 C CB  . MET B 1 228 ? 125.076 119.331 126.527 1.00 63.70  ?  204  MET R CB  1 
ATOM 4063 C CG  . MET B 1 228 ? 125.989 119.996 127.534 1.00 63.70  ?  204  MET R CG  1 
ATOM 4064 S SD  . MET B 1 228 ? 127.316 120.943 126.776 1.00 63.70  ?  204  MET R SD  1 
ATOM 4065 C CE  . MET B 1 228 ? 128.468 121.029 128.144 1.00 63.70  ?  204  MET R CE  1 
ATOM 4066 N N   . VAL B 1 229 ? 122.313 118.193 125.559 1.00 63.62  ?  205  VAL R N   1 
ATOM 4067 C CA  . VAL B 1 229 ? 121.507 117.483 124.570 1.00 63.62  ?  205  VAL R CA  1 
ATOM 4068 C C   . VAL B 1 229 ? 120.319 118.334 124.137 1.00 63.62  ?  205  VAL R C   1 
ATOM 4069 O O   . VAL B 1 229 ? 119.941 118.348 122.957 1.00 63.62  ?  205  VAL R O   1 
ATOM 4070 C CB  . VAL B 1 229 ? 121.069 116.120 125.132 1.00 63.62  ?  205  VAL R CB  1 
ATOM 4071 C CG1 . VAL B 1 229 ? 119.804 115.646 124.471 1.00 63.62  ?  205  VAL R CG1 1 
ATOM 4072 C CG2 . VAL B 1 229 ? 122.176 115.100 124.944 1.00 63.62  ?  205  VAL R CG2 1 
ATOM 4073 N N   . PHE B 1 230 ? 119.716 119.061 125.079 1.00 64.02  ?  206  PHE R N   1 
ATOM 4074 C CA  . PHE B 1 230 ? 118.597 119.931 124.737 1.00 64.02  ?  206  PHE R CA  1 
ATOM 4075 C C   . PHE B 1 230 ? 119.022 121.015 123.762 1.00 64.02  ?  206  PHE R C   1 
ATOM 4076 O O   . PHE B 1 230 ? 118.293 121.328 122.812 1.00 64.02  ?  206  PHE R O   1 
ATOM 4077 C CB  . PHE B 1 230 ? 118.008 120.559 125.995 1.00 64.02  ?  206  PHE R CB  1 
ATOM 4078 C CG  . PHE B 1 230 ? 116.659 121.174 125.786 1.00 64.02  ?  206  PHE R CG  1 
ATOM 4079 C CD1 . PHE B 1 230 ? 115.544 120.383 125.620 1.00 64.02  ?  206  PHE R CD1 1 
ATOM 4080 C CD2 . PHE B 1 230 ? 116.507 122.545 125.759 1.00 64.02  ?  206  PHE R CD2 1 
ATOM 4081 C CE1 . PHE B 1 230 ? 114.304 120.945 125.430 1.00 64.02  ?  206  PHE R CE1 1 
ATOM 4082 C CE2 . PHE B 1 230 ? 115.269 123.113 125.570 1.00 64.02  ?  206  PHE R CE2 1 
ATOM 4083 C CZ  . PHE B 1 230 ? 114.166 122.312 125.405 1.00 64.02  ?  206  PHE R CZ  1 
ATOM 4084 N N   . GLY B 1 231 ? 120.195 121.608 123.983 1.00 62.37  ?  207  GLY R N   1 
ATOM 4085 C CA  . GLY B 1 231 ? 120.688 122.601 123.038 1.00 62.37  ?  207  GLY R CA  1 
ATOM 4086 C C   . GLY B 1 231 ? 120.893 122.030 121.646 1.00 62.37  ?  207  GLY R C   1 
ATOM 4087 O O   . GLY B 1 231 ? 120.507 122.646 120.640 1.00 62.37  ?  207  GLY R O   1 
ATOM 4088 N N   . ILE B 1 232 ? 121.500 120.842 121.569 1.00 58.14  ?  208  ILE R N   1 
ATOM 4089 C CA  . ILE B 1 232 ? 121.703 120.200 120.271 1.00 58.14  ?  208  ILE R CA  1 
ATOM 4090 C C   . ILE B 1 232 ? 120.366 120.003 119.569 1.00 58.14  ?  208  ILE R C   1 
ATOM 4091 O O   . ILE B 1 232 ? 120.211 120.316 118.380 1.00 58.14  ?  208  ILE R O   1 
ATOM 4092 C CB  . ILE B 1 232 ? 122.439 118.860 120.437 1.00 58.14  ?  208  ILE R CB  1 
ATOM 4093 C CG1 . ILE B 1 232 ? 123.851 119.070 120.968 1.00 58.14  ?  208  ILE R CG1 1 
ATOM 4094 C CG2 . ILE B 1 232 ? 122.503 118.133 119.112 1.00 58.14  ?  208  ILE R CG2 1 
ATOM 4095 C CD1 . ILE B 1 232 ? 124.573 120.191 120.324 1.00 58.14  ?  208  ILE R CD1 1 
ATOM 4096 N N   . MET B 1 233 ? 119.378 119.481 120.302 1.00 64.19  ?  209  MET R N   1 
ATOM 4097 C CA  . MET B 1 233 ? 118.064 119.233 119.718 1.00 64.19  ?  209  MET R CA  1 
ATOM 4098 C C   . MET B 1 233 ? 117.431 120.522 119.218 1.00 64.19  ?  209  MET R C   1 
ATOM 4099 O O   . MET B 1 233 ? 116.822 120.548 118.140 1.00 64.19  ?  209  MET R O   1 
ATOM 4100 C CB  . MET B 1 233 ? 117.147 118.569 120.743 1.00 64.19  ?  209  MET R CB  1 
ATOM 4101 C CG  . MET B 1 233 ? 116.227 117.510 120.177 1.00 64.19  ?  209  MET R CG  1 
ATOM 4102 S SD  . MET B 1 233 ? 117.037 115.924 119.971 1.00 64.19  ?  209  MET R SD  1 
ATOM 4103 C CE  . MET B 1 233 ? 117.951 115.816 121.499 1.00 64.19  ?  209  MET R CE  1 
ATOM 4104 N N   . LEU B 1 234 ? 117.545 121.597 120.000 1.00 58.48  ?  210  LEU R N   1 
ATOM 4105 C CA  . LEU B 1 234 ? 116.932 122.861 119.611 1.00 58.48  ?  210  LEU R CA  1 
ATOM 4106 C C   . LEU B 1 234 ? 117.515 123.364 118.301 1.00 58.48  ?  210  LEU R C   1 
ATOM 4107 O O   . LEU B 1 234 ? 116.779 123.772 117.391 1.00 58.48  ?  210  LEU R O   1 
ATOM 4108 C CB  . LEU B 1 234 ? 117.129 123.893 120.716 1.00 58.48  ?  210  LEU R CB  1 
ATOM 4109 C CG  . LEU B 1 234 ? 116.104 125.016 120.820 1.00 58.48  ?  210  LEU R CG  1 
ATOM 4110 C CD1 . LEU B 1 234 ? 115.875 125.375 122.275 1.00 58.48  ?  210  LEU R CD1 1 
ATOM 4111 C CD2 . LEU B 1 234 ? 116.555 126.232 120.035 1.00 58.48  ?  210  LEU R CD2 1 
ATOM 4112 N N   . GLN B 1 235 ? 118.841 123.324 118.179 1.00 59.64  ?  211  GLN R N   1 
ATOM 4113 C CA  . GLN B 1 235 ? 119.460 123.836 116.961 1.00 59.64  ?  211  GLN R CA  1 
ATOM 4114 C C   . GLN B 1 235 ? 119.099 122.952 115.769 1.00 59.64  ?  211  GLN R C   1 
ATOM 4115 O O   . GLN B 1 235 ? 118.811 123.457 114.673 1.00 59.64  ?  211  GLN R O   1 
ATOM 4116 C CB  . GLN B 1 235 ? 120.973 123.947 117.178 1.00 59.64  ?  211  GLN R CB  1 
ATOM 4117 C CG  . GLN B 1 235 ? 121.733 124.945 116.298 1.00 59.64  ?  211  GLN R CG  1 
ATOM 4118 C CD  . GLN B 1 235 ? 121.592 124.739 114.818 1.00 59.64  ?  211  GLN R CD  1 
ATOM 4119 O OE1 . GLN B 1 235 ? 121.424 123.619 114.347 1.00 59.64  ?  211  GLN R OE1 1 
ATOM 4120 N NE2 . GLN B 1 235 ? 121.655 125.830 114.066 1.00 59.64  ?  211  GLN R NE2 1 
ATOM 4121 N N   . LEU B 1 236 ? 119.062 121.631 115.978 1.00 57.89  ?  212  LEU R N   1 
ATOM 4122 C CA  . LEU B 1 236 ? 118.673 120.723 114.902 1.00 57.89  ?  212  LEU R CA  1 
ATOM 4123 C C   . LEU B 1 236 ? 117.269 121.027 114.405 1.00 57.89  ?  212  LEU R C   1 
ATOM 4124 O O   . LEU B 1 236 ? 117.024 121.076 113.191 1.00 57.89  ?  212  LEU R O   1 
ATOM 4125 C CB  . LEU B 1 236 ? 118.741 119.275 115.380 1.00 57.89  ?  212  LEU R CB  1 
ATOM 4126 C CG  . LEU B 1 236 ? 119.975 118.426 115.097 1.00 57.89  ?  212  LEU R CG  1 
ATOM 4127 C CD1 . LEU B 1 236 ? 120.073 118.125 113.623 1.00 57.89  ?  212  LEU R CD1 1 
ATOM 4128 C CD2 . LEU B 1 236 ? 121.223 119.100 115.583 1.00 57.89  ?  212  LEU R CD2 1 
ATOM 4129 N N   . TYR B 1 237 ? 116.327 121.223 115.328 1.00 63.43  ?  213  TYR R N   1 
ATOM 4130 C CA  . TYR B 1 237 ? 114.950 121.446 114.913 1.00 63.43  ?  213  TYR R CA  1 
ATOM 4131 C C   . TYR B 1 237 ? 114.790 122.802 114.251 1.00 63.43  ?  213  TYR R C   1 
ATOM 4132 O O   . TYR B 1 237 ? 113.982 122.945 113.326 1.00 63.43  ?  213  TYR R O   1 
ATOM 4133 C CB  . TYR B 1 237 ? 114.005 121.298 116.102 1.00 63.43  ?  213  TYR R CB  1 
ATOM 4134 C CG  . TYR B 1 237 ? 113.282 119.977 116.088 1.00 63.43  ?  213  TYR R CG  1 
ATOM 4135 C CD1 . TYR B 1 237 ? 112.237 119.743 115.212 1.00 63.43  ?  213  TYR R CD1 1 
ATOM 4136 C CD2 . TYR B 1 237 ? 113.679 118.945 116.925 1.00 63.43  ?  213  TYR R CD2 1 
ATOM 4137 C CE1 . TYR B 1 237 ? 111.589 118.526 115.187 1.00 63.43  ?  213  TYR R CE1 1 
ATOM 4138 C CE2 . TYR B 1 237 ? 113.039 117.727 116.908 1.00 63.43  ?  213  TYR R CE2 1 
ATOM 4139 C CZ  . TYR B 1 237 ? 111.995 117.521 116.038 1.00 63.43  ?  213  TYR R CZ  1 
ATOM 4140 O OH  . TYR B 1 237 ? 111.359 116.302 116.021 1.00 63.43  ?  213  TYR R OH  1 
ATOM 4141 N N   . ALA B 1 238 ? 115.563 123.800 114.683 1.00 58.67  ?  214  ALA R N   1 
ATOM 4142 C CA  . ALA B 1 238 ? 115.552 125.078 113.981 1.00 58.67  ?  214  ALA R CA  1 
ATOM 4143 C C   . ALA B 1 238 ? 115.995 124.904 112.534 1.00 58.67  ?  214  ALA R C   1 
ATOM 4144 O O   . ALA B 1 238 ? 115.357 125.424 111.609 1.00 58.67  ?  214  ALA R O   1 
ATOM 4145 C CB  . ALA B 1 238 ? 116.446 126.084 114.702 1.00 58.67  ?  214  ALA R CB  1 
ATOM 4146 N N   . GLN B 1 239 ? 117.077 124.153 112.315 1.00 55.72  ?  215  GLN R N   1 
ATOM 4147 C CA  . GLN B 1 239 ? 117.546 123.936 110.947 1.00 55.72  ?  215  GLN R CA  1 
ATOM 4148 C C   . GLN B 1 239 ? 116.514 123.195 110.110 1.00 55.72  ?  215  GLN R C   1 
ATOM 4149 O O   . GLN B 1 239 ? 116.261 123.561 108.955 1.00 55.72  ?  215  GLN R O   1 
ATOM 4150 C CB  . GLN B 1 239 ? 118.862 123.165 110.951 1.00 55.72  ?  215  GLN R CB  1 
ATOM 4151 C CG  . GLN B 1 239 ? 120.033 123.960 111.455 1.00 55.72  ?  215  GLN R CG  1 
ATOM 4152 C CD  . GLN B 1 239 ? 120.836 124.556 110.328 1.00 55.72  ?  215  GLN R CD  1 
ATOM 4153 O OE1 . GLN B 1 239 ? 120.281 125.116 109.385 1.00 55.72  ?  215  GLN R OE1 1 
ATOM 4154 N NE2 . GLN B 1 239 ? 122.151 124.430 110.411 1.00 55.72  ?  215  GLN R NE2 1 
ATOM 4155 N N   . ILE B 1 240 ? 115.910 122.147 110.669 1.00 59.56  ?  216  ILE R N   1 
ATOM 4156 C CA  . ILE B 1 240 ? 114.968 121.359 109.881 1.00 59.56  ?  216  ILE R CA  1 
ATOM 4157 C C   . ILE B 1 240 ? 113.723 122.178 109.555 1.00 59.56  ?  216  ILE R C   1 
ATOM 4158 O O   . ILE B 1 240 ? 113.189 122.101 108.441 1.00 59.56  ?  216  ILE R O   1 
ATOM 4159 C CB  . ILE B 1 240 ? 114.635 120.033 110.593 1.00 59.56  ?  216  ILE R CB  1 
ATOM 4160 C CG1 . ILE B 1 240 ? 114.154 118.995 109.585 1.00 59.56  ?  216  ILE R CG1 1 
ATOM 4161 C CG2 . ILE B 1 240 ? 113.602 120.212 111.692 1.00 59.56  ?  216  ILE R CG2 1 
ATOM 4162 C CD1 . ILE B 1 240 ? 114.174 117.586 110.120 1.00 59.56  ?  216  ILE R CD1 1 
ATOM 4163 N N   . CYS B 1 241 ? 113.257 123.000 110.502 1.00 67.59  ?  217  CYS R N   1 
ATOM 4164 C CA  . CYS B 1 241 ? 112.098 123.844 110.235 1.00 67.59  ?  217  CYS R CA  1 
ATOM 4165 C C   . CYS B 1 241 ? 112.420 124.898 109.189 1.00 67.59  ?  217  CYS R C   1 
ATOM 4166 O O   . CYS B 1 241 ? 111.569 125.236 108.358 1.00 67.59  ?  217  CYS R O   1 
ATOM 4167 C CB  . CYS B 1 241 ? 111.613 124.499 111.526 1.00 67.59  ?  217  CYS R CB  1 
ATOM 4168 S SG  . CYS B 1 241 ? 110.042 125.373 111.369 1.00 67.59  ?  217  CYS R SG  1 
ATOM 4169 N N   . ARG B 1 242 ? 113.641 125.433 109.215 1.00 65.38  ?  218  ARG R N   1 
ATOM 4170 C CA  . ARG B 1 242 ? 114.049 126.371 108.178 1.00 65.38  ?  218  ARG R CA  1 
ATOM 4171 C C   . ARG B 1 242 ? 114.067 125.707 106.809 1.00 65.38  ?  218  ARG R C   1 
ATOM 4172 O O   . ARG B 1 242 ? 113.642 126.306 105.815 1.00 65.38  ?  218  ARG R O   1 
ATOM 4173 C CB  . ARG B 1 242 ? 115.423 126.949 108.509 1.00 65.38  ?  218  ARG R CB  1 
ATOM 4174 C CG  . ARG B 1 242 ? 116.287 127.241 107.297 1.00 65.38  ?  218  ARG R CG  1 
ATOM 4175 C CD  . ARG B 1 242 ? 115.993 128.610 106.729 1.00 65.38  ?  218  ARG R CD  1 
ATOM 4176 N NE  . ARG B 1 242 ? 116.110 129.649 107.743 1.00 65.38  ?  218  ARG R NE  1 
ATOM 4177 C CZ  . ARG B 1 242 ? 117.259 130.092 108.233 1.00 65.38  ?  218  ARG R CZ  1 
ATOM 4178 N NH1 . ARG B 1 242 ? 118.419 129.610 107.820 1.00 65.38  1  218  ARG R NH1 1 
ATOM 4179 N NH2 . ARG B 1 242 ? 117.243 131.044 109.161 1.00 65.38  ?  218  ARG R NH2 1 
ATOM 4180 N N   . ILE B 1 243 ? 114.544 124.467 106.736 1.00 60.16  ?  219  ILE R N   1 
ATOM 4181 C CA  . ILE B 1 243 ? 114.789 123.838 105.442 1.00 60.16  ?  219  ILE R CA  1 
ATOM 4182 C C   . ILE B 1 243 ? 113.535 123.188 104.870 1.00 60.16  ?  219  ILE R C   1 
ATOM 4183 O O   . ILE B 1 243 ? 113.486 122.881 103.674 1.00 60.16  ?  219  ILE R O   1 
ATOM 4184 C CB  . ILE B 1 243 ? 115.934 122.815 105.541 1.00 60.16  ?  219  ILE R CB  1 
ATOM 4185 C CG1 . ILE B 1 243 ? 116.708 122.767 104.227 1.00 60.16  ?  219  ILE R CG1 1 
ATOM 4186 C CG2 . ILE B 1 243 ? 115.400 121.438 105.900 1.00 60.16  ?  219  ILE R CG2 1 
ATOM 4187 C CD1 . ILE B 1 243 ? 117.769 121.696 104.187 1.00 60.16  ?  219  ILE R CD1 1 
ATOM 4188 N N   . VAL B 1 244 ? 112.514 122.963 105.696 1.00 62.86  ?  220  VAL R N   1 
ATOM 4189 C CA  . VAL B 1 244 ? 111.261 122.408 105.191 1.00 62.86  ?  220  VAL R CA  1 
ATOM 4190 C C   . VAL B 1 244 ? 110.283 123.496 104.778 1.00 62.86  ?  220  VAL R C   1 
ATOM 4191 O O   . VAL B 1 244 ? 109.282 123.202 104.118 1.00 62.86  ?  220  VAL R O   1 
ATOM 4192 C CB  . VAL B 1 244 ? 110.600 121.455 106.197 1.00 62.86  ?  220  VAL R CB  1 
ATOM 4193 C CG1 . VAL B 1 244 ? 111.512 120.279 106.503 1.00 62.86  ?  220  VAL R CG1 1 
ATOM 4194 C CG2 . VAL B 1 244 ? 110.204 122.203 107.455 1.00 62.86  ?  220  VAL R CG2 1 
ATOM 4195 N N   . CYS B 1 245 ? 110.532 124.746 105.156 1.00 75.00  ?  221  CYS R N   1 
ATOM 4196 C CA  . CYS B 1 245 ? 109.662 125.859 104.786 1.00 75.00  ?  221  CYS R CA  1 
ATOM 4197 C C   . CYS B 1 245 ? 110.193 126.457 103.487 1.00 75.00  ?  221  CYS R C   1 
ATOM 4198 O O   . CYS B 1 245 ? 110.370 127.667 103.355 1.00 75.00  ?  221  CYS R O   1 
ATOM 4199 C CB  . CYS B 1 245 ? 109.591 126.896 105.896 1.00 75.00  ?  221  CYS R CB  1 
ATOM 4200 S SG  . CYS B 1 245 ? 108.115 126.770 106.928 1.00 75.00  ?  221  CYS R SG  1 
ATOM 4201 N N   . ARG B 1 246 ? 110.453 125.584 102.521 1.00 81.65  ?  222  ARG R N   1 
ATOM 4202 C CA  . ARG B 1 246 ? 110.769 126.000 101.164 1.00 81.65  ?  222  ARG R CA  1 
ATOM 4203 C C   . ARG B 1 246 ? 109.956 125.139 100.215 1.00 81.65  ?  222  ARG R C   1 
ATOM 4204 O O   . ARG B 1 246 ? 109.689 125.528 99.075  1.00 81.65  ?  222  ARG R O   1 
ATOM 4205 C CB  . ARG B 1 246 ? 112.264 125.873 100.879 1.00 81.65  ?  222  ARG R CB  1 
ATOM 4206 C CG  . ARG B 1 246 ? 112.959 127.197 100.615 1.00 81.65  ?  222  ARG R CG  1 
ATOM 4207 C CD  . ARG B 1 246 ? 114.465 127.016 100.516 1.00 81.65  ?  222  ARG R CD  1 
ATOM 4208 N NE  . ARG B 1 246 ? 115.171 127.662 101.616 1.00 81.65  ?  222  ARG R NE  1 
ATOM 4209 C CZ  . ARG B 1 246 ? 115.507 128.944 101.644 1.00 81.65  ?  222  ARG R CZ  1 
ATOM 4210 N NH1 . ARG B 1 246 ? 115.214 129.757 100.642 1.00 81.65  1  222  ARG R NH1 1 
ATOM 4211 N NH2 . ARG B 1 246 ? 116.154 129.422 102.702 1.00 81.65  ?  222  ARG R NH2 1 
ATOM 4212 N N   . HIS B 1 247 ? 109.555 123.965 100.690 1.00 83.62  ?  223  HIS R N   1 
ATOM 4213 C CA  . HIS B 1 247 ? 108.617 123.111 99.970  1.00 83.62  ?  223  HIS R CA  1 
ATOM 4214 C C   . HIS B 1 247 ? 107.178 123.469 100.284 1.00 83.62  ?  223  HIS R C   1 
ATOM 4215 O O   . HIS B 1 247 ? 106.260 122.702 99.991  1.00 83.62  ?  223  HIS R O   1 
ATOM 4216 C CB  . HIS B 1 247 ? 108.893 121.646 100.293 1.00 83.62  ?  223  HIS R CB  1 
ATOM 4217 C CG  . HIS B 1 247 ? 110.236 121.168 99.842  1.00 83.62  ?  223  HIS R CG  1 
ATOM 4218 N ND1 . HIS B 1 247 ? 111.191 122.013 99.319  1.00 83.62  ?  223  HIS R ND1 1 
ATOM 4219 C CD2 . HIS B 1 247 ? 110.785 119.932 99.838  1.00 83.62  ?  223  HIS R CD2 1 
ATOM 4220 C CE1 . HIS B 1 247 ? 112.270 121.317 99.011  1.00 83.62  ?  223  HIS R CE1 1 
ATOM 4221 N NE2 . HIS B 1 247 ? 112.050 120.051 99.316  1.00 83.62  ?  223  HIS R NE2 1 
ATOM 4222 N N   . ALA B 1 248 ? 106.964 124.629 100.898 1.00 96.72  ?  224  ALA R N   1 
ATOM 4223 C CA  . ALA B 1 248 ? 105.623 125.107 101.196 1.00 96.72  ?  224  ALA R CA  1 
ATOM 4224 C C   . ALA B 1 248 ? 105.370 126.408 100.454 1.00 96.72  ?  224  ALA R C   1 
ATOM 4225 O O   . ALA B 1 248 ? 104.257 126.654 99.981  1.00 96.72  ?  224  ALA R O   1 
ATOM 4226 C CB  . ALA B 1 248 ? 105.437 125.297 102.702 1.00 96.72  ?  224  ALA R CB  1 
ATOM 4227 N N   . ALA B 1 265 ? 99.183  123.581 104.478 1.00 148.18 ?  241  ALA R N   1 
ATOM 4228 C CA  . ALA B 1 265 ? 100.442 124.078 103.936 1.00 148.18 ?  241  ALA R CA  1 
ATOM 4229 C C   . ALA B 1 265 ? 101.472 124.275 105.044 1.00 148.18 ?  241  ALA R C   1 
ATOM 4230 O O   . ALA B 1 265 ? 101.931 123.311 105.657 1.00 148.18 ?  241  ALA R O   1 
ATOM 4231 C CB  . ALA B 1 265 ? 100.217 125.380 103.181 1.00 148.18 ?  241  ALA R CB  1 
ATOM 4232 N N   . THR B 1 266 ? 101.834 125.536 105.293 1.00 144.80 ?  242  THR R N   1 
ATOM 4233 C CA  . THR B 1 266 ? 102.803 125.848 106.338 1.00 144.80 ?  242  THR R CA  1 
ATOM 4234 C C   . THR B 1 266 ? 102.266 125.550 107.732 1.00 144.80 ?  242  THR R C   1 
ATOM 4235 O O   . THR B 1 266 ? 103.056 125.254 108.637 1.00 144.80 ?  242  THR R O   1 
ATOM 4236 C CB  . THR B 1 266 ? 103.218 127.319 106.244 1.00 144.80 ?  242  THR R CB  1 
ATOM 4237 O OG1 . THR B 1 266 ? 103.474 127.657 104.875 1.00 144.80 ?  242  THR R OG1 1 
ATOM 4238 C CG2 . THR B 1 266 ? 104.475 127.579 107.062 1.00 144.80 ?  242  THR R CG2 1 
ATOM 4239 N N   . ARG B 1 267 ? 100.944 125.618 107.921 1.00 144.72 ?  243  ARG R N   1 
ATOM 4240 C CA  . ARG B 1 267 ? 100.368 125.410 109.246 1.00 144.72 ?  243  ARG R CA  1 
ATOM 4241 C C   . ARG B 1 267 ? 100.676 124.015 109.776 1.00 144.72 ?  243  ARG R C   1 
ATOM 4242 O O   . ARG B 1 267 ? 101.079 123.862 110.934 1.00 144.72 ?  243  ARG R O   1 
ATOM 4243 C CB  . ARG B 1 267 ? 98.857  125.644 109.203 1.00 144.72 ?  243  ARG R CB  1 
ATOM 4244 C CG  . ARG B 1 267 ? 98.133  125.299 110.497 1.00 144.72 ?  243  ARG R CG  1 
ATOM 4245 C CD  . ARG B 1 267 ? 97.312  124.024 110.350 1.00 144.72 ?  243  ARG R CD  1 
ATOM 4246 N NE  . ARG B 1 267 ? 96.813  123.541 111.632 1.00 144.72 ?  243  ARG R NE  1 
ATOM 4247 C CZ  . ARG B 1 267 ? 96.210  122.373 111.808 1.00 144.72 ?  243  ARG R CZ  1 
ATOM 4248 N NH1 . ARG B 1 267 ? 96.013  121.537 110.802 1.00 144.72 1  243  ARG R NH1 1 
ATOM 4249 N NH2 . ARG B 1 267 ? 95.796  122.034 113.026 1.00 144.72 ?  243  ARG R NH2 1 
ATOM 4250 N N   . LYS B 1 268 ? 100.500 122.988 108.942 1.00 142.25 ?  244  LYS R N   1 
ATOM 4251 C CA  . LYS B 1 268 ? 100.753 121.620 109.383 1.00 142.25 ?  244  LYS R CA  1 
ATOM 4252 C C   . LYS B 1 268 ? 102.209 121.434 109.790 1.00 142.25 ?  244  LYS R C   1 
ATOM 4253 O O   . LYS B 1 268 ? 102.506 120.871 110.852 1.00 142.25 ?  244  LYS R O   1 
ATOM 4254 C CB  . LYS B 1 268 ? 100.372 120.637 108.275 1.00 142.25 ?  244  LYS R CB  1 
ATOM 4255 C CG  . LYS B 1 268 ? 100.799 119.202 108.537 1.00 142.25 ?  244  LYS R CG  1 
ATOM 4256 C CD  . LYS B 1 268 ? 100.562 118.328 107.315 1.00 142.25 ?  244  LYS R CD  1 
ATOM 4257 C CE  . LYS B 1 268 ? 101.082 116.916 107.533 1.00 142.25 ?  244  LYS R CE  1 
ATOM 4258 N NZ  . LYS B 1 268 ? 102.530 116.904 107.877 1.00 142.25 1  244  LYS R NZ  1 
ATOM 4259 N N   . GLY B 1 269 ? 103.135 121.920 108.960 1.00 134.57 ?  245  GLY R N   1 
ATOM 4260 C CA  . GLY B 1 269 ? 104.545 121.761 109.268 1.00 134.57 ?  245  GLY R CA  1 
ATOM 4261 C C   . GLY B 1 269 ? 104.963 122.500 110.524 1.00 134.57 ?  245  GLY R C   1 
ATOM 4262 O O   . GLY B 1 269 ? 105.676 121.949 111.370 1.00 134.57 ?  245  GLY R O   1 
ATOM 4263 N N   . ILE B 1 270 ? 104.530 123.756 110.668 1.00 127.65 ?  246  ILE R N   1 
ATOM 4264 C CA  . ILE B 1 270 ? 104.927 124.523 111.844 1.00 127.65 ?  246  ILE R CA  1 
ATOM 4265 C C   . ILE B 1 270 ? 104.298 123.934 113.101 1.00 127.65 ?  246  ILE R C   1 
ATOM 4266 O O   . ILE B 1 270 ? 104.939 123.876 114.157 1.00 127.65 ?  246  ILE R O   1 
ATOM 4267 C CB  . ILE B 1 270 ? 104.592 126.018 111.669 1.00 127.65 ?  246  ILE R CB  1 
ATOM 4268 C CG1 . ILE B 1 270 ? 105.278 126.842 112.760 1.00 127.65 ?  246  ILE R CG1 1 
ATOM 4269 C CG2 . ILE B 1 270 ? 103.089 126.265 111.676 1.00 127.65 ?  246  ILE R CG2 1 
ATOM 4270 C CD1 . ILE B 1 270 ? 105.152 128.336 112.568 1.00 127.65 ?  246  ILE R CD1 1 
ATOM 4271 N N   . ALA B 1 271 ? 103.054 123.455 113.007 1.00 121.90 ?  247  ALA R N   1 
ATOM 4272 C CA  . ALA B 1 271 ? 102.432 122.812 114.156 1.00 121.90 ?  247  ALA R CA  1 
ATOM 4273 C C   . ALA B 1 271 ? 103.187 121.552 114.549 1.00 121.90 ?  247  ALA R C   1 
ATOM 4274 O O   . ALA B 1 271 ? 103.432 121.313 115.737 1.00 121.90 ?  247  ALA R O   1 
ATOM 4275 C CB  . ALA B 1 271 ? 100.970 122.491 113.851 1.00 121.90 ?  247  ALA R CB  1 
ATOM 4276 N N   . THR B 1 272 ? 103.581 120.741 113.566 1.00 117.39 ?  248  THR R N   1 
ATOM 4277 C CA  . THR B 1 272 ? 104.315 119.520 113.878 1.00 117.39 ?  248  THR R CA  1 
ATOM 4278 C C   . THR B 1 272 ? 105.650 119.841 114.539 1.00 117.39 ?  248  THR R C   1 
ATOM 4279 O O   . THR B 1 272 ? 105.986 119.289 115.596 1.00 117.39 ?  248  THR R O   1 
ATOM 4280 C CB  . THR B 1 272 ? 104.527 118.697 112.606 1.00 117.39 ?  248  THR R CB  1 
ATOM 4281 O OG1 . THR B 1 272 ? 103.273 118.157 112.170 1.00 117.39 ?  248  THR R OG1 1 
ATOM 4282 C CG2 . THR B 1 272 ? 105.501 117.556 112.864 1.00 117.39 ?  248  THR R CG2 1 
ATOM 4283 N N   . LEU B 1 273 ? 106.418 120.747 113.944 1.00 105.11 ?  249  LEU R N   1 
ATOM 4284 C CA  . LEU B 1 273 ? 107.748 121.050 114.449 1.00 105.11 ?  249  LEU R CA  1 
ATOM 4285 C C   . LEU B 1 273 ? 107.729 121.929 115.691 1.00 105.11 ?  249  LEU R C   1 
ATOM 4286 O O   . LEU B 1 273 ? 108.784 122.136 116.300 1.00 105.11 ?  249  LEU R O   1 
ATOM 4287 C CB  . LEU B 1 273 ? 108.591 121.705 113.353 1.00 105.11 ?  249  LEU R CB  1 
ATOM 4288 C CG  . LEU B 1 273 ? 108.586 120.939 112.029 1.00 105.11 ?  249  LEU R CG  1 
ATOM 4289 C CD1 . LEU B 1 273 ? 109.172 121.782 110.913 1.00 105.11 ?  249  LEU R CD1 1 
ATOM 4290 C CD2 . LEU B 1 273 ? 109.338 119.624 112.167 1.00 105.11 ?  249  LEU R CD2 1 
ATOM 4291 N N   . ALA B 1 274 ? 106.567 122.451 116.084 1.00 101.67 ?  250  ALA R N   1 
ATOM 4292 C CA  . ALA B 1 274 ? 106.435 123.137 117.357 1.00 101.67 ?  250  ALA R CA  1 
ATOM 4293 C C   . ALA B 1 274 ? 105.803 122.278 118.442 1.00 101.67 ?  250  ALA R C   1 
ATOM 4294 O O   . ALA B 1 274 ? 105.930 122.616 119.623 1.00 101.67 ?  250  ALA R O   1 
ATOM 4295 C CB  . ALA B 1 274 ? 105.612 124.423 117.187 1.00 101.67 ?  250  ALA R CB  1 
ATOM 4296 N N   . VAL B 1 275 ? 105.131 121.190 118.084 1.00 96.21  ?  251  VAL R N   1 
ATOM 4297 C CA  . VAL B 1 275 ? 104.531 120.300 119.066 1.00 96.21  ?  251  VAL R CA  1 
ATOM 4298 C C   . VAL B 1 275 ? 105.468 119.161 119.446 1.00 96.21  ?  251  VAL R C   1 
ATOM 4299 O O   . VAL B 1 275 ? 105.576 118.819 120.624 1.00 96.21  ?  251  VAL R O   1 
ATOM 4300 C CB  . VAL B 1 275 ? 103.180 119.763 118.548 1.00 96.21  ?  251  VAL R CB  1 
ATOM 4301 C CG1 . VAL B 1 275 ? 102.716 118.589 119.388 1.00 96.21  ?  251  VAL R CG1 1 
ATOM 4302 C CG2 . VAL B 1 275 ? 102.136 120.864 118.578 1.00 96.21  ?  251  VAL R CG2 1 
ATOM 4303 N N   . VAL B 1 276 ? 106.154 118.554 118.473 1.00 91.84  ?  252  VAL R N   1 
ATOM 4304 C CA  . VAL B 1 276 ? 107.030 117.431 118.804 1.00 91.84  ?  252  VAL R CA  1 
ATOM 4305 C C   . VAL B 1 276 ? 108.234 117.892 119.618 1.00 91.84  ?  252  VAL R C   1 
ATOM 4306 O O   . VAL B 1 276 ? 108.808 117.114 120.388 1.00 91.84  ?  252  VAL R O   1 
ATOM 4307 C CB  . VAL B 1 276 ? 107.446 116.665 117.534 1.00 91.84  ?  252  VAL R CB  1 
ATOM 4308 C CG1 . VAL B 1 276 ? 106.256 116.474 116.616 1.00 91.84  ?  252  VAL R CG1 1 
ATOM 4309 C CG2 . VAL B 1 276 ? 108.544 117.410 116.805 1.00 91.84  ?  252  VAL R CG2 1 
ATOM 4310 N N   . LEU B 1 277 ? 108.643 119.151 119.464 1.00 88.70  ?  253  LEU R N   1 
ATOM 4311 C CA  . LEU B 1 277 ? 109.691 119.676 120.331 1.00 88.70  ?  253  LEU R CA  1 
ATOM 4312 C C   . LEU B 1 277 ? 109.200 119.939 121.746 1.00 88.70  ?  253  LEU R C   1 
ATOM 4313 O O   . LEU B 1 277 ? 109.883 119.560 122.706 1.00 88.70  ?  253  LEU R O   1 
ATOM 4314 C CB  . LEU B 1 277 ? 110.272 120.964 119.751 1.00 88.70  ?  253  LEU R CB  1 
ATOM 4315 C CG  . LEU B 1 277 ? 111.212 121.735 120.681 1.00 88.70  ?  253  LEU R CG  1 
ATOM 4316 C CD1 . LEU B 1 277 ? 112.492 120.959 120.914 1.00 88.70  ?  253  LEU R CD1 1 
ATOM 4317 C CD2 . LEU B 1 277 ? 111.513 123.117 120.121 1.00 88.70  ?  253  LEU R CD2 1 
ATOM 4318 N N   . GLY B 1 278 ? 108.032 120.553 121.899 1.00 86.72  ?  254  GLY R N   1 
ATOM 4319 C CA  . GLY B 1 278 ? 107.489 120.831 123.211 1.00 86.72  ?  254  GLY R CA  1 
ATOM 4320 C C   . GLY B 1 278 ? 107.123 119.573 123.966 1.00 86.72  ?  254  GLY R C   1 
ATOM 4321 O O   . GLY B 1 278 ? 107.121 119.565 125.198 1.00 86.72  ?  254  GLY R O   1 
ATOM 4322 N N   . ALA B 1 279 ? 106.813 118.500 123.237 1.00 82.43  ?  255  ALA R N   1 
ATOM 4323 C CA  . ALA B 1 279 ? 106.498 117.237 123.894 1.00 82.43  ?  255  ALA R CA  1 
ATOM 4324 C C   . ALA B 1 279 ? 107.680 116.734 124.710 1.00 82.43  ?  255  ALA R C   1 
ATOM 4325 O O   . ALA B 1 279 ? 107.511 116.269 125.842 1.00 82.43  ?  255  ALA R O   1 
ATOM 4326 C CB  . ALA B 1 279 ? 106.079 116.196 122.858 1.00 82.43  ?  255  ALA R CB  1 
ATOM 4327 N N   . PHE B 1 280 ? 108.885 116.820 124.152 1.00 79.03  ?  256  PHE R N   1 
ATOM 4328 C CA  . PHE B 1 280 ? 110.083 116.419 124.876 1.00 79.03  ?  256  PHE R CA  1 
ATOM 4329 C C   . PHE B 1 280 ? 110.593 117.517 125.798 1.00 79.03  ?  256  PHE R C   1 
ATOM 4330 O O   . PHE B 1 280 ? 111.261 117.212 126.792 1.00 79.03  ?  256  PHE R O   1 
ATOM 4331 C CB  . PHE B 1 280 ? 111.160 115.987 123.873 1.00 79.03  ?  256  PHE R CB  1 
ATOM 4332 C CG  . PHE B 1 280 ? 112.570 116.052 124.395 1.00 79.03  ?  256  PHE R CG  1 
ATOM 4333 C CD1 . PHE B 1 280 ? 113.303 117.223 124.330 1.00 79.03  ?  256  PHE R CD1 1 
ATOM 4334 C CD2 . PHE B 1 280 ? 113.188 114.914 124.873 1.00 79.03  ?  256  PHE R CD2 1 
ATOM 4335 C CE1 . PHE B 1 280 ? 114.597 117.269 124.787 1.00 79.03  ?  256  PHE R CE1 1 
ATOM 4336 C CE2 . PHE B 1 280 ? 114.485 114.956 125.332 1.00 79.03  ?  256  PHE R CE2 1 
ATOM 4337 C CZ  . PHE B 1 280 ? 115.190 116.136 125.286 1.00 79.03  ?  256  PHE R CZ  1 
ATOM 4338 N N   . ALA B 1 281 ? 110.291 118.781 125.501 1.00 82.69  ?  257  ALA R N   1 
ATOM 4339 C CA  . ALA B 1 281 ? 110.763 119.891 126.316 1.00 82.69  ?  257  ALA R CA  1 
ATOM 4340 C C   . ALA B 1 281 ? 109.962 120.102 127.591 1.00 82.69  ?  257  ALA R C   1 
ATOM 4341 O O   . ALA B 1 281 ? 110.512 120.620 128.568 1.00 82.69  ?  257  ALA R O   1 
ATOM 4342 C CB  . ALA B 1 281 ? 110.747 121.190 125.502 1.00 82.69  ?  257  ALA R CB  1 
ATOM 4343 N N   . ALA B 1 282 ? 108.687 119.725 127.610 1.00 84.13  ?  258  ALA R N   1 
ATOM 4344 C CA  . ALA B 1 282 ? 107.813 120.001 128.739 1.00 84.13  ?  258  ALA R CA  1 
ATOM 4345 C C   . ALA B 1 282 ? 107.537 118.779 129.600 1.00 84.13  ?  258  ALA R C   1 
ATOM 4346 O O   . ALA B 1 282 ? 106.891 118.908 130.644 1.00 84.13  ?  258  ALA R O   1 
ATOM 4347 C CB  . ALA B 1 282 ? 106.486 120.593 128.248 1.00 84.13  ?  258  ALA R CB  1 
ATOM 4348 N N   . CYS B 1 283 ? 108.003 117.601 129.196 1.00 84.24  ?  259  CYS R N   1 
ATOM 4349 C CA  . CYS B 1 283 ? 107.812 116.396 129.983 1.00 84.24  ?  259  CYS R CA  1 
ATOM 4350 C C   . CYS B 1 283 ? 109.087 115.910 130.651 1.00 84.24  ?  259  CYS R C   1 
ATOM 4351 O O   . CYS B 1 283 ? 109.015 115.038 131.523 1.00 84.24  ?  259  CYS R O   1 
ATOM 4352 C CB  . CYS B 1 283 ? 107.238 115.272 129.110 1.00 84.24  ?  259  CYS R CB  1 
ATOM 4353 S SG  . CYS B 1 283 ? 105.660 115.671 128.328 1.00 84.24  ?  259  CYS R SG  1 
ATOM 4354 N N   . TRP B 1 284 ? 110.244 116.441 130.268 1.00 79.85  ?  260  TRP R N   1 
ATOM 4355 C CA  . TRP B 1 284 ? 111.505 116.068 130.884 1.00 79.85  ?  260  TRP R CA  1 
ATOM 4356 C C   . TRP B 1 284 ? 112.161 117.209 131.637 1.00 79.85  ?  260  TRP R C   1 
ATOM 4357 O O   . TRP B 1 284 ? 113.267 117.028 132.157 1.00 79.85  ?  260  TRP R O   1 
ATOM 4358 C CB  . TRP B 1 284 ? 112.480 115.532 129.831 1.00 79.85  ?  260  TRP R CB  1 
ATOM 4359 C CG  . TRP B 1 284 ? 112.696 114.060 129.908 1.00 79.85  ?  260  TRP R CG  1 
ATOM 4360 C CD1 . TRP B 1 284 ? 112.404 113.141 128.949 1.00 79.85  ?  260  TRP R CD1 1 
ATOM 4361 C CD2 . TRP B 1 284 ? 113.264 113.335 131.001 1.00 79.85  ?  260  TRP R CD2 1 
ATOM 4362 N NE1 . TRP B 1 284 ? 112.748 111.886 129.377 1.00 79.85  ?  260  TRP R NE1 1 
ATOM 4363 C CE2 . TRP B 1 284 ? 113.279 111.978 130.636 1.00 79.85  ?  260  TRP R CE2 1 
ATOM 4364 C CE3 . TRP B 1 284 ? 113.758 113.701 132.255 1.00 79.85  ?  260  TRP R CE3 1 
ATOM 4365 C CZ2 . TRP B 1 284 ? 113.770 110.984 131.478 1.00 79.85  ?  260  TRP R CZ2 1 
ATOM 4366 C CZ3 . TRP B 1 284 ? 114.245 112.714 133.090 1.00 79.85  ?  260  TRP R CZ3 1 
ATOM 4367 C CH2 . TRP B 1 284 ? 114.247 111.372 132.699 1.00 79.85  ?  260  TRP R CH2 1 
ATOM 4368 N N   . LEU B 1 285 ? 111.530 118.370 131.712 1.00 74.96  ?  261  LEU R N   1 
ATOM 4369 C CA  . LEU B 1 285 ? 112.143 119.443 132.475 1.00 74.96  ?  261  LEU R CA  1 
ATOM 4370 C C   . LEU B 1 285 ? 111.187 119.983 133.544 1.00 74.96  ?  261  LEU R C   1 
ATOM 4371 O O   . LEU B 1 285 ? 111.129 121.198 133.772 1.00 74.96  ?  261  LEU R O   1 
ATOM 4372 C CB  . LEU B 1 285 ? 112.589 120.533 131.488 1.00 74.96  ?  261  LEU R CB  1 
ATOM 4373 C CG  . LEU B 1 285 ? 113.216 121.887 131.818 1.00 74.96  ?  261  LEU R CG  1 
ATOM 4374 C CD1 . LEU B 1 285 ? 114.703 121.734 132.045 1.00 74.96  ?  261  LEU R CD1 1 
ATOM 4375 C CD2 . LEU B 1 285 ? 112.955 122.861 130.690 1.00 74.96  ?  261  LEU R CD2 1 
ATOM 4376 N N   . PRO B 1 286 ? 110.412 119.127 134.219 1.00 75.38  ?  262  PRO R N   1 
ATOM 4377 C CA  . PRO B 1 286 ? 110.065 119.421 135.612 1.00 75.38  ?  262  PRO R CA  1 
ATOM 4378 C C   . PRO B 1 286 ? 111.163 118.977 136.561 1.00 75.38  ?  262  PRO R C   1 
ATOM 4379 O O   . PRO B 1 286 ? 111.345 119.557 137.636 1.00 75.38  ?  262  PRO R O   1 
ATOM 4380 C CB  . PRO B 1 286 ? 108.799 118.588 135.854 1.00 75.38  ?  262  PRO R CB  1 
ATOM 4381 C CG  . PRO B 1 286 ? 108.325 118.141 134.522 1.00 75.38  ?  262  PRO R CG  1 
ATOM 4382 C CD  . PRO B 1 286 ? 109.207 118.721 133.477 1.00 75.38  ?  262  PRO R CD  1 
ATOM 4383 N N   . PHE B 1 287 ? 111.908 117.949 136.161 1.00 74.80  ?  263  PHE R N   1 
ATOM 4384 C CA  . PHE B 1 287 ? 112.789 117.214 137.058 1.00 74.80  ?  263  PHE R CA  1 
ATOM 4385 C C   . PHE B 1 287 ? 114.214 117.741 137.073 1.00 74.80  ?  263  PHE R C   1 
ATOM 4386 O O   . PHE B 1 287 ? 114.779 117.951 138.151 1.00 74.80  ?  263  PHE R O   1 
ATOM 4387 C CB  . PHE B 1 287 ? 112.800 115.727 136.676 1.00 74.80  ?  263  PHE R CB  1 
ATOM 4388 C CG  . PHE B 1 287 ? 113.629 114.874 137.589 1.00 74.80  ?  263  PHE R CG  1 
ATOM 4389 C CD1 . PHE B 1 287 ? 113.072 114.299 138.714 1.00 74.80  ?  263  PHE R CD1 1 
ATOM 4390 C CD2 . PHE B 1 287 ? 114.964 114.641 137.318 1.00 74.80  ?  263  PHE R CD2 1 
ATOM 4391 C CE1 . PHE B 1 287 ? 113.833 113.514 139.554 1.00 74.80  ?  263  PHE R CE1 1 
ATOM 4392 C CE2 . PHE B 1 287 ? 115.728 113.859 138.155 1.00 74.80  ?  263  PHE R CE2 1 
ATOM 4393 C CZ  . PHE B 1 287 ? 115.163 113.294 139.273 1.00 74.80  ?  263  PHE R CZ  1 
ATOM 4394 N N   . THR B 1 288 ? 114.818 117.957 135.904 1.00 70.79  ?  264  THR R N   1 
ATOM 4395 C CA  . THR B 1 288 ? 116.216 118.362 135.868 1.00 70.79  ?  264  THR R CA  1 
ATOM 4396 C C   . THR B 1 288 ? 116.438 119.738 136.478 1.00 70.79  ?  264  THR R C   1 
ATOM 4397 O O   . THR B 1 288 ? 117.587 120.103 136.750 1.00 70.79  ?  264  THR R O   1 
ATOM 4398 C CB  . THR B 1 288 ? 116.736 118.332 134.436 1.00 70.79  ?  264  THR R CB  1 
ATOM 4399 O OG1 . THR B 1 288 ? 116.423 119.570 133.790 1.00 70.79  ?  264  THR R OG1 1 
ATOM 4400 C CG2 . THR B 1 288 ? 116.098 117.188 133.677 1.00 70.79  ?  264  THR R CG2 1 
ATOM 4401 N N   . VAL B 1 289 ? 115.375 120.510 136.697 1.00 72.18  ?  265  VAL R N   1 
ATOM 4402 C CA  . VAL B 1 289 ? 115.518 121.748 137.453 1.00 72.18  ?  265  VAL R CA  1 
ATOM 4403 C C   . VAL B 1 289 ? 115.471 121.467 138.948 1.00 72.18  ?  265  VAL R C   1 
ATOM 4404 O O   . VAL B 1 289 ? 116.204 122.084 139.729 1.00 72.18  ?  265  VAL R O   1 
ATOM 4405 C CB  . VAL B 1 289 ? 114.443 122.763 137.032 1.00 72.18  ?  265  VAL R CB  1 
ATOM 4406 C CG1 . VAL B 1 289 ? 114.880 124.169 137.395 1.00 72.18  ?  265  VAL R CG1 1 
ATOM 4407 C CG2 . VAL B 1 289 ? 114.172 122.656 135.545 1.00 72.18  ?  265  VAL R CG2 1 
ATOM 4408 N N   . TYR B 1 290 ? 114.612 120.537 139.374 1.00 76.44  ?  266  TYR R N   1 
ATOM 4409 C CA  . TYR B 1 290 ? 114.615 120.109 140.769 1.00 76.44  ?  266  TYR R CA  1 
ATOM 4410 C C   . TYR B 1 290 ? 115.929 119.434 141.131 1.00 76.44  ?  266  TYR R C   1 
ATOM 4411 O O   . TYR B 1 290 ? 116.292 119.365 142.309 1.00 76.44  ?  266  TYR R O   1 
ATOM 4412 C CB  . TYR B 1 290 ? 113.445 119.161 141.026 1.00 76.44  ?  266  TYR R CB  1 
ATOM 4413 C CG  . TYR B 1 290 ? 113.028 119.024 142.474 1.00 76.44  ?  266  TYR R CG  1 
ATOM 4414 C CD1 . TYR B 1 290 ? 113.653 119.747 143.475 1.00 76.44  ?  266  TYR R CD1 1 
ATOM 4415 C CD2 . TYR B 1 290 ? 112.017 118.150 142.838 1.00 76.44  ?  266  TYR R CD2 1 
ATOM 4416 C CE1 . TYR B 1 290 ? 113.276 119.614 144.792 1.00 76.44  ?  266  TYR R CE1 1 
ATOM 4417 C CE2 . TYR B 1 290 ? 111.633 118.011 144.152 1.00 76.44  ?  266  TYR R CE2 1 
ATOM 4418 C CZ  . TYR B 1 290 ? 112.265 118.745 145.125 1.00 76.44  ?  266  TYR R CZ  1 
ATOM 4419 O OH  . TYR B 1 290 ? 111.884 118.609 146.439 1.00 76.44  ?  266  TYR R OH  1 
ATOM 4420 N N   . CYS B 1 291 ? 116.654 118.937 140.130 1.00 77.30  ?  267  CYS R N   1 
ATOM 4421 C CA  . CYS B 1 291 ? 117.933 118.287 140.379 1.00 77.30  ?  267  CYS R CA  1 
ATOM 4422 C C   . CYS B 1 291 ? 118.920 119.221 141.063 1.00 77.30  ?  267  CYS R C   1 
ATOM 4423 O O   . CYS B 1 291 ? 119.803 118.762 141.795 1.00 77.30  ?  267  CYS R O   1 
ATOM 4424 C CB  . CYS B 1 291 ? 118.507 117.780 139.058 1.00 77.30  ?  267  CYS R CB  1 
ATOM 4425 S SG  . CYS B 1 291 ? 120.042 116.868 139.205 1.00 77.30  ?  267  CYS R SG  1 
ATOM 4426 N N   . LEU B 1 292 ? 118.788 120.527 140.844 1.00 74.94  ?  268  LEU R N   1 
ATOM 4427 C CA  . LEU B 1 292 ? 119.730 121.506 141.368 1.00 74.94  ?  268  LEU R CA  1 
ATOM 4428 C C   . LEU B 1 292 ? 119.204 122.236 142.598 1.00 74.94  ?  268  LEU R C   1 
ATOM 4429 O O   . LEU B 1 292 ? 119.867 122.251 143.638 1.00 74.94  ?  268  LEU R O   1 
ATOM 4430 C CB  . LEU B 1 292 ? 120.084 122.515 140.272 1.00 74.94  ?  268  LEU R CB  1 
ATOM 4431 C CG  . LEU B 1 292 ? 120.346 121.909 138.894 1.00 74.94  ?  268  LEU R CG  1 
ATOM 4432 C CD1 . LEU B 1 292 ? 120.681 122.990 137.885 1.00 74.94  ?  268  LEU R CD1 1 
ATOM 4433 C CD2 . LEU B 1 292 ? 121.460 120.882 138.966 1.00 74.94  ?  268  LEU R CD2 1 
ATOM 4434 N N   . LEU B 1 293 ? 118.018 122.836 142.505 1.00 73.56  ?  269  LEU R N   1 
ATOM 4435 C CA  . LEU B 1 293 ? 117.457 123.625 143.603 1.00 73.56  ?  269  LEU R CA  1 
ATOM 4436 C C   . LEU B 1 293 ? 116.745 122.704 144.593 1.00 73.56  ?  269  LEU R C   1 
ATOM 4437 O O   . LEU B 1 293 ? 115.519 122.600 144.634 1.00 73.56  ?  269  LEU R O   1 
ATOM 4438 C CB  . LEU B 1 293 ? 116.512 124.686 143.060 1.00 73.56  ?  269  LEU R CB  1 
ATOM 4439 C CG  . LEU B 1 293 ? 116.959 125.418 141.801 1.00 73.56  ?  269  LEU R CG  1 
ATOM 4440 C CD1 . LEU B 1 293 ? 115.753 125.877 141.007 1.00 73.56  ?  269  LEU R CD1 1 
ATOM 4441 C CD2 . LEU B 1 293 ? 117.832 126.601 142.171 1.00 73.56  ?  269  LEU R CD2 1 
ATOM 4442 N N   . GLY B 1 294 ? 117.546 122.031 145.407 1.00 79.61  ?  270  GLY R N   1 
ATOM 4443 C CA  . GLY B 1 294 ? 116.993 121.154 146.423 1.00 79.61  ?  270  GLY R CA  1 
ATOM 4444 C C   . GLY B 1 294 ? 118.101 120.474 147.193 1.00 79.61  ?  270  GLY R C   1 
ATOM 4445 O O   . GLY B 1 294 ? 119.280 120.548 146.832 1.00 79.61  ?  270  GLY R O   1 
ATOM 4446 N N   . ASP B 1 295 ? 117.699 119.805 148.269 1.00 82.13  ?  271  ASP R N   1 
ATOM 4447 C CA  . ASP B 1 295 ? 118.623 119.053 149.105 1.00 82.13  ?  271  ASP R CA  1 
ATOM 4448 C C   . ASP B 1 295 ? 117.860 117.923 149.786 1.00 82.13  ?  271  ASP R C   1 
ATOM 4449 O O   . ASP B 1 295 ? 116.680 117.691 149.513 1.00 82.13  ?  271  ASP R O   1 
ATOM 4450 C CB  . ASP B 1 295 ? 119.380 120.001 150.060 1.00 82.13  ?  271  ASP R CB  1 
ATOM 4451 C CG  . ASP B 1 295 ? 118.667 120.258 151.399 1.00 82.13  ?  271  ASP R CG  1 
ATOM 4452 O OD1 . ASP B 1 295 ? 117.588 119.706 151.696 1.00 82.13  ?  271  ASP R OD1 1 
ATOM 4453 O OD2 . ASP B 1 295 ? 119.224 121.050 152.188 1.00 82.13  -1 271  ASP R OD2 1 
ATOM 4454 N N   . ALA B 1 296 ? 118.552 117.211 150.677 1.00 80.36  ?  272  ALA R N   1 
ATOM 4455 C CA  . ALA B 1 296 ? 117.944 116.060 151.336 1.00 80.36  ?  272  ALA R CA  1 
ATOM 4456 C C   . ALA B 1 296 ? 116.754 116.472 152.191 1.00 80.36  ?  272  ALA R C   1 
ATOM 4457 O O   . ALA B 1 296 ? 115.709 115.811 152.175 1.00 80.36  ?  272  ALA R O   1 
ATOM 4458 C CB  . ALA B 1 296 ? 118.985 115.329 152.183 1.00 80.36  ?  272  ALA R CB  1 
ATOM 4459 N N   . HIS B 1 297 ? 116.887 117.567 152.938 1.00 89.37  ?  273  HIS R N   1 
ATOM 4460 C CA  . HIS B 1 297 ? 115.817 118.044 153.813 1.00 89.37  ?  273  HIS R CA  1 
ATOM 4461 C C   . HIS B 1 297 ? 114.773 118.780 152.972 1.00 89.37  ?  273  HIS R C   1 
ATOM 4462 O O   . HIS B 1 297 ? 114.576 119.993 153.068 1.00 89.37  ?  273  HIS R O   1 
ATOM 4463 C CB  . HIS B 1 297 ? 116.384 118.928 154.913 1.00 89.37  ?  273  HIS R CB  1 
ATOM 4464 C CG  . HIS B 1 297 ? 117.529 118.308 155.652 1.00 89.37  ?  273  HIS R CG  1 
ATOM 4465 N ND1 . HIS B 1 297 ? 118.773 118.132 155.086 1.00 89.37  ?  273  HIS R ND1 1 
ATOM 4466 C CD2 . HIS B 1 297 ? 117.616 117.818 156.911 1.00 89.37  ?  273  HIS R CD2 1 
ATOM 4467 C CE1 . HIS B 1 297 ? 119.578 117.562 155.965 1.00 89.37  ?  273  HIS R CE1 1 
ATOM 4468 N NE2 . HIS B 1 297 ? 118.901 117.361 157.081 1.00 89.37  ?  273  HIS R NE2 1 
ATOM 4469 N N   . SER B 1 298 ? 114.094 118.007 152.132 1.00 81.75  ?  274  SER R N   1 
ATOM 4470 C CA  . SER B 1 298 ? 113.086 118.504 151.213 1.00 81.75  ?  274  SER R CA  1 
ATOM 4471 C C   . SER B 1 298 ? 111.812 117.692 151.374 1.00 81.75  ?  274  SER R C   1 
ATOM 4472 O O   . SER B 1 298 ? 111.870 116.502 151.696 1.00 81.75  ?  274  SER R O   1 
ATOM 4473 C CB  . SER B 1 298 ? 113.577 118.413 149.761 1.00 81.75  ?  274  SER R CB  1 
ATOM 4474 O OG  . SER B 1 298 ? 112.666 119.015 148.860 1.00 81.75  ?  274  SER R OG  1 
ATOM 4475 N N   . PRO B 1 299 ? 110.650 118.307 151.165 1.00 82.22  ?  275  PRO R N   1 
ATOM 4476 C CA  . PRO B 1 299 ? 109.403 117.560 151.298 1.00 82.22  ?  275  PRO R CA  1 
ATOM 4477 C C   . PRO B 1 299 ? 109.341 116.442 150.280 1.00 82.22  ?  275  PRO R C   1 
ATOM 4478 O O   . PRO B 1 299 ? 109.865 116.568 149.157 1.00 82.22  ?  275  PRO R O   1 
ATOM 4479 C CB  . PRO B 1 299 ? 108.320 118.618 151.043 1.00 82.22  ?  275  PRO R CB  1 
ATOM 4480 C CG  . PRO B 1 299 ? 108.992 119.923 150.965 1.00 82.22  ?  275  PRO R CG  1 
ATOM 4481 C CD  . PRO B 1 299 ? 110.451 119.730 150.848 1.00 82.22  ?  275  PRO R CD  1 
ATOM 4482 N N   . PRO B 1 300 ? 108.709 115.321 150.625 1.00 82.66  ?  276  PRO R N   1 
ATOM 4483 C CA  . PRO B 1 300 ? 108.653 114.176 149.711 1.00 82.66  ?  276  PRO R CA  1 
ATOM 4484 C C   . PRO B 1 300 ? 107.568 114.263 148.650 1.00 82.66  ?  276  PRO R C   1 
ATOM 4485 O O   . PRO B 1 300 ? 107.596 113.468 147.704 1.00 82.66  ?  276  PRO R O   1 
ATOM 4486 C CB  . PRO B 1 300 ? 108.383 112.999 150.664 1.00 82.66  ?  276  PRO R CB  1 
ATOM 4487 C CG  . PRO B 1 300 ? 107.910 113.613 151.972 1.00 82.66  ?  276  PRO R CG  1 
ATOM 4488 C CD  . PRO B 1 300 ? 107.887 115.102 151.823 1.00 82.66  ?  276  PRO R CD  1 
ATOM 4489 N N   . LEU B 1 301 ? 106.625 115.195 148.775 1.00 83.95  ?  277  LEU R N   1 
ATOM 4490 C CA  . LEU B 1 301 ? 105.604 115.354 147.749 1.00 83.95  ?  277  LEU R CA  1 
ATOM 4491 C C   . LEU B 1 301 ? 106.175 115.957 146.475 1.00 83.95  ?  277  LEU R C   1 
ATOM 4492 O O   . LEU B 1 301 ? 105.713 115.633 145.377 1.00 83.95  ?  277  LEU R O   1 
ATOM 4493 C CB  . LEU B 1 301 ? 104.463 116.223 148.280 1.00 83.95  ?  277  LEU R CB  1 
ATOM 4494 C CG  . LEU B 1 301 ? 103.455 116.800 147.283 1.00 83.95  ?  277  LEU R CG  1 
ATOM 4495 C CD1 . LEU B 1 301 ? 102.722 115.691 146.541 1.00 83.95  ?  277  LEU R CD1 1 
ATOM 4496 C CD2 . LEU B 1 301 ? 102.470 117.721 147.988 1.00 83.95  ?  277  LEU R CD2 1 
ATOM 4497 N N   . TYR B 1 302 ? 107.186 116.812 146.598 1.00 83.58  ?  278  TYR R N   1 
ATOM 4498 C CA  . TYR B 1 302 ? 107.725 117.521 145.448 1.00 83.58  ?  278  TYR R CA  1 
ATOM 4499 C C   . TYR B 1 302 ? 108.541 116.632 144.523 1.00 83.58  ?  278  TYR R C   1 
ATOM 4500 O O   . TYR B 1 302 ? 108.781 117.020 143.375 1.00 83.58  ?  278  TYR R O   1 
ATOM 4501 C CB  . TYR B 1 302 ? 108.584 118.694 145.919 1.00 83.58  ?  278  TYR R CB  1 
ATOM 4502 C CG  . TYR B 1 302 ? 107.825 119.995 146.018 1.00 83.58  ?  278  TYR R CG  1 
ATOM 4503 C CD1 . TYR B 1 302 ? 106.699 120.223 145.243 1.00 83.58  ?  278  TYR R CD1 1 
ATOM 4504 C CD2 . TYR B 1 302 ? 108.233 120.992 146.889 1.00 83.58  ?  278  TYR R CD2 1 
ATOM 4505 C CE1 . TYR B 1 302 ? 106.001 121.409 145.331 1.00 83.58  ?  278  TYR R CE1 1 
ATOM 4506 C CE2 . TYR B 1 302 ? 107.544 122.180 146.985 1.00 83.58  ?  278  TYR R CE2 1 
ATOM 4507 C CZ  . TYR B 1 302 ? 106.428 122.385 146.204 1.00 83.58  ?  278  TYR R CZ  1 
ATOM 4508 O OH  . TYR B 1 302 ? 105.736 123.570 146.297 1.00 83.58  ?  278  TYR R OH  1 
ATOM 4509 N N   . THR B 1 303 ? 108.966 115.459 144.979 1.00 76.83  ?  279  THR R N   1 
ATOM 4510 C CA  . THR B 1 303 ? 109.739 114.542 144.153 1.00 76.83  ?  279  THR R CA  1 
ATOM 4511 C C   . THR B 1 303 ? 108.869 113.523 143.439 1.00 76.83  ?  279  THR R C   1 
ATOM 4512 O O   . THR B 1 303 ? 109.060 113.279 142.245 1.00 76.83  ?  279  THR R O   1 
ATOM 4513 C CB  . THR B 1 303 ? 110.776 113.810 145.009 1.00 76.83  ?  279  THR R CB  1 
ATOM 4514 O OG1 . THR B 1 303 ? 111.809 114.725 145.390 1.00 76.83  ?  279  THR R OG1 1 
ATOM 4515 C CG2 . THR B 1 303 ? 111.394 112.658 144.238 1.00 76.83  ?  279  THR R CG2 1 
ATOM 4516 N N   . TYR B 1 304 ? 107.904 112.931 144.141 1.00 81.31  ?  280  TYR R N   1 
ATOM 4517 C CA  . TYR B 1 304 ? 107.056 111.919 143.530 1.00 81.31  ?  280  TYR R CA  1 
ATOM 4518 C C   . TYR B 1 304 ? 106.161 112.497 142.446 1.00 81.31  ?  280  TYR R C   1 
ATOM 4519 O O   . TYR B 1 304 ? 105.638 111.738 141.624 1.00 81.31  ?  280  TYR R O   1 
ATOM 4520 C CB  . TYR B 1 304 ? 106.208 111.238 144.601 1.00 81.31  ?  280  TYR R CB  1 
ATOM 4521 C CG  . TYR B 1 304 ? 106.669 109.843 144.927 1.00 81.31  ?  280  TYR R CG  1 
ATOM 4522 C CD1 . TYR B 1 304 ? 108.006 109.577 145.178 1.00 81.31  ?  280  TYR R CD1 1 
ATOM 4523 C CD2 . TYR B 1 304 ? 105.774 108.792 144.983 1.00 81.31  ?  280  TYR R CD2 1 
ATOM 4524 C CE1 . TYR B 1 304 ? 108.436 108.300 145.477 1.00 81.31  ?  280  TYR R CE1 1 
ATOM 4525 C CE2 . TYR B 1 304 ? 106.191 107.512 145.281 1.00 81.31  ?  280  TYR R CE2 1 
ATOM 4526 C CZ  . TYR B 1 304 ? 107.523 107.271 145.527 1.00 81.31  ?  280  TYR R CZ  1 
ATOM 4527 O OH  . TYR B 1 304 ? 107.944 105.995 145.824 1.00 81.31  ?  280  TYR R OH  1 
ATOM 4528 N N   . LEU B 1 305 ? 105.974 113.814 142.424 1.00 82.30  ?  281  LEU R N   1 
ATOM 4529 C CA  . LEU B 1 305 ? 105.126 114.447 141.422 1.00 82.30  ?  281  LEU R CA  1 
ATOM 4530 C C   . LEU B 1 305 ? 105.887 114.774 140.145 1.00 82.30  ?  281  LEU R C   1 
ATOM 4531 O O   . LEU B 1 305 ? 105.363 114.571 139.044 1.00 82.30  ?  281  LEU R O   1 
ATOM 4532 C CB  . LEU B 1 305 ? 104.498 115.720 141.994 1.00 82.30  ?  281  LEU R CB  1 
ATOM 4533 C CG  . LEU B 1 305 ? 103.862 116.685 140.994 1.00 82.30  ?  281  LEU R CG  1 
ATOM 4534 C CD1 . LEU B 1 305 ? 102.638 116.057 140.343 1.00 82.30  ?  281  LEU R CD1 1 
ATOM 4535 C CD2 . LEU B 1 305 ? 103.498 117.997 141.671 1.00 82.30  ?  281  LEU R CD2 1 
ATOM 4536 N N   . THR B 1 306 ? 107.118 115.270 140.266 1.00 82.02  ?  282  THR R N   1 
ATOM 4537 C CA  . THR B 1 306 ? 107.891 115.639 139.089 1.00 82.02  ?  282  THR R CA  1 
ATOM 4538 C C   . THR B 1 306 ? 108.410 114.434 138.316 1.00 82.02  ?  282  THR R C   1 
ATOM 4539 O O   . THR B 1 306 ? 108.859 114.602 137.178 1.00 82.02  ?  282  THR R O   1 
ATOM 4540 C CB  . THR B 1 306 ? 109.065 116.532 139.483 1.00 82.02  ?  282  THR R CB  1 
ATOM 4541 O OG1 . THR B 1 306 ? 109.868 116.800 138.328 1.00 82.02  ?  282  THR R OG1 1 
ATOM 4542 C CG2 . THR B 1 306 ? 109.921 115.851 140.533 1.00 82.02  ?  282  THR R CG2 1 
ATOM 4543 N N   . LEU B 1 307 ? 108.375 113.236 138.899 1.00 74.43  ?  283  LEU R N   1 
ATOM 4544 C CA  . LEU B 1 307 ? 108.842 112.055 138.188 1.00 74.43  ?  283  LEU R CA  1 
ATOM 4545 C C   . LEU B 1 307 ? 107.780 111.454 137.280 1.00 74.43  ?  283  LEU R C   1 
ATOM 4546 O O   . LEU B 1 307 ? 108.119 110.656 136.401 1.00 74.43  ?  283  LEU R O   1 
ATOM 4547 C CB  . LEU B 1 307 ? 109.323 110.998 139.180 1.00 74.43  ?  283  LEU R CB  1 
ATOM 4548 C CG  . LEU B 1 307 ? 110.461 110.113 138.680 1.00 74.43  ?  283  LEU R CG  1 
ATOM 4549 C CD1 . LEU B 1 307 ? 111.531 110.954 138.009 1.00 74.43  ?  283  LEU R CD1 1 
ATOM 4550 C CD2 . LEU B 1 307 ? 111.052 109.301 139.818 1.00 74.43  ?  283  LEU R CD2 1 
ATOM 4551 N N   . LEU B 1 308 ? 106.511 111.809 137.474 1.00 81.91  ?  284  LEU R N   1 
ATOM 4552 C CA  . LEU B 1 308 ? 105.463 111.320 136.583 1.00 81.91  ?  284  LEU R CA  1 
ATOM 4553 C C   . LEU B 1 308 ? 105.632 111.773 135.135 1.00 81.91  ?  284  LEU R C   1 
ATOM 4554 O O   . LEU B 1 308 ? 105.424 110.941 134.232 1.00 81.91  ?  284  LEU R O   1 
ATOM 4555 C CB  . LEU B 1 308 ? 104.089 111.737 137.121 1.00 81.91  ?  284  LEU R CB  1 
ATOM 4556 C CG  . LEU B 1 308 ? 103.248 110.644 137.781 1.00 81.91  ?  284  LEU R CG  1 
ATOM 4557 C CD1 . LEU B 1 308 ? 102.673 109.701 136.736 1.00 81.91  ?  284  LEU R CD1 1 
ATOM 4558 C CD2 . LEU B 1 308 ? 104.066 109.885 138.809 1.00 81.91  ?  284  LEU R CD2 1 
ATOM 4559 N N   . PRO B 1 309 ? 105.972 113.033 134.836 1.00 80.29  ?  285  PRO R N   1 
ATOM 4560 C CA  . PRO B 1 309 ? 106.118 113.423 133.426 1.00 80.29  ?  285  PRO R CA  1 
ATOM 4561 C C   . PRO B 1 309 ? 107.148 112.614 132.662 1.00 80.29  ?  285  PRO R C   1 
ATOM 4562 O O   . PRO B 1 309 ? 107.002 112.450 131.447 1.00 80.29  ?  285  PRO R O   1 
ATOM 4563 C CB  . PRO B 1 309 ? 106.515 114.901 133.518 1.00 80.29  ?  285  PRO R CB  1 
ATOM 4564 C CG  . PRO B 1 309 ? 105.900 115.359 134.775 1.00 80.29  ?  285  PRO R CG  1 
ATOM 4565 C CD  . PRO B 1 309 ? 106.043 114.209 135.721 1.00 80.29  ?  285  PRO R CD  1 
ATOM 4566 N N   . ALA B 1 310 ? 108.186 112.102 133.324 1.00 79.37  ?  286  ALA R N   1 
ATOM 4567 C CA  . ALA B 1 310 ? 109.148 111.258 132.624 1.00 79.37  ?  286  ALA R CA  1 
ATOM 4568 C C   . ALA B 1 310 ? 108.479 109.997 132.090 1.00 79.37  ?  286  ALA R C   1 
ATOM 4569 O O   . ALA B 1 310 ? 108.646 109.635 130.918 1.00 79.37  ?  286  ALA R O   1 
ATOM 4570 C CB  . ALA B 1 310 ? 110.308 110.907 133.552 1.00 79.37  ?  286  ALA R CB  1 
ATOM 4571 N N   . THR B 1 311 ? 107.695 109.325 132.934 1.00 84.59  ?  287  THR R N   1 
ATOM 4572 C CA  . THR B 1 311 ? 106.985 108.133 132.486 1.00 84.59  ?  287  THR R CA  1 
ATOM 4573 C C   . THR B 1 311 ? 105.926 108.479 131.447 1.00 84.59  ?  287  THR R C   1 
ATOM 4574 O O   . THR B 1 311 ? 105.685 107.704 130.512 1.00 84.59  ?  287  THR R O   1 
ATOM 4575 C CB  . THR B 1 311 ? 106.352 107.423 133.678 1.00 84.59  ?  287  THR R CB  1 
ATOM 4576 O OG1 . THR B 1 311 ? 105.452 108.318 134.342 1.00 84.59  ?  287  THR R OG1 1 
ATOM 4577 C CG2 . THR B 1 311 ? 107.424 106.980 134.656 1.00 84.59  ?  287  THR R CG2 1 
ATOM 4578 N N   . TYR B 1 312 ? 105.282 109.639 131.593 1.00 88.89  ?  288  TYR R N   1 
ATOM 4579 C CA  . TYR B 1 312 ? 104.307 110.059 130.592 1.00 88.89  ?  288  TYR R CA  1 
ATOM 4580 C C   . TYR B 1 312 ? 104.965 110.255 129.231 1.00 88.89  ?  288  TYR R C   1 
ATOM 4581 O O   . TYR B 1 312 ? 104.412 109.852 128.202 1.00 88.89  ?  288  TYR R O   1 
ATOM 4582 C CB  . TYR B 1 312 ? 103.607 111.338 131.045 1.00 88.89  ?  288  TYR R CB  1 
ATOM 4583 C CG  . TYR B 1 312 ? 102.413 111.092 131.936 1.00 88.89  ?  288  TYR R CG  1 
ATOM 4584 C CD1 . TYR B 1 312 ? 101.932 109.807 132.144 1.00 88.89  ?  288  TYR R CD1 1 
ATOM 4585 C CD2 . TYR B 1 312 ? 101.767 112.144 132.570 1.00 88.89  ?  288  TYR R CD2 1 
ATOM 4586 C CE1 . TYR B 1 312 ? 100.841 109.576 132.957 1.00 88.89  ?  288  TYR R CE1 1 
ATOM 4587 C CE2 . TYR B 1 312 ? 100.674 111.923 133.385 1.00 88.89  ?  288  TYR R CE2 1 
ATOM 4588 C CZ  . TYR B 1 312 ? 100.215 110.637 133.576 1.00 88.89  ?  288  TYR R CZ  1 
ATOM 4589 O OH  . TYR B 1 312 ? 99.127  110.413 134.388 1.00 88.89  ?  288  TYR R OH  1 
ATOM 4590 N N   . ASN B 1 313 ? 106.146 110.875 129.205 1.00 82.69  ?  289  ASN R N   1 
ATOM 4591 C CA  . ASN B 1 313 ? 106.873 111.025 127.949 1.00 82.69  ?  289  ASN R CA  1 
ATOM 4592 C C   . ASN B 1 313 ? 107.286 109.671 127.399 1.00 82.69  ?  289  ASN R C   1 
ATOM 4593 O O   . ASN B 1 313 ? 107.265 109.456 126.183 1.00 82.69  ?  289  ASN R O   1 
ATOM 4594 C CB  . ASN B 1 313 ? 108.095 111.923 128.147 1.00 82.69  ?  289  ASN R CB  1 
ATOM 4595 C CG  . ASN B 1 313 ? 109.101 111.812 127.009 1.00 82.69  ?  289  ASN R CG  1 
ATOM 4596 O OD1 . ASN B 1 313 ? 109.818 110.819 126.882 1.00 82.69  ?  289  ASN R OD1 1 
ATOM 4597 N ND2 . ASN B 1 313 ? 109.155 112.841 126.173 1.00 82.69  ?  289  ASN R ND2 1 
ATOM 4598 N N   . SER B 1 314 ? 107.686 108.753 128.277 1.00 84.52  ?  290  SER R N   1 
ATOM 4599 C CA  . SER B 1 314 ? 108.030 107.411 127.821 1.00 84.52  ?  290  SER R CA  1 
ATOM 4600 C C   . SER B 1 314 ? 106.842 106.740 127.147 1.00 84.52  ?  290  SER R C   1 
ATOM 4601 O O   . SER B 1 314 ? 107.006 106.018 126.158 1.00 84.52  ?  290  SER R O   1 
ATOM 4602 C CB  . SER B 1 314 ? 108.523 106.569 128.994 1.00 84.52  ?  290  SER R CB  1 
ATOM 4603 O OG  . SER B 1 314 ? 108.152 105.214 128.828 1.00 84.52  ?  290  SER R OG  1 
ATOM 4604 N N   . MET B 1 315 ? 105.638 106.958 127.675 1.00 89.87  ?  291  MET R N   1 
ATOM 4605 C CA  . MET B 1 315 ? 104.447 106.366 127.071 1.00 89.87  ?  291  MET R CA  1 
ATOM 4606 C C   . MET B 1 315 ? 104.003 107.102 125.810 1.00 89.87  ?  291  MET R C   1 
ATOM 4607 O O   . MET B 1 315 ? 103.384 106.493 124.932 1.00 89.87  ?  291  MET R O   1 
ATOM 4608 C CB  . MET B 1 315 ? 103.304 106.324 128.089 1.00 89.87  ?  291  MET R CB  1 
ATOM 4609 C CG  . MET B 1 315 ? 102.230 107.382 127.896 1.00 89.87  ?  291  MET R CG  1 
ATOM 4610 S SD  . MET B 1 315 ? 100.841 107.168 129.025 1.00 89.87  ?  291  MET R SD  1 
ATOM 4611 C CE  . MET B 1 315 ? 100.426 105.451 128.728 1.00 89.87  ?  291  MET R CE  1 
ATOM 4612 N N   . ILE B 1 316 ? 104.298 108.398 125.705 1.00 84.03  ?  292  ILE R N   1 
ATOM 4613 C CA  . ILE B 1 316 ? 103.844 109.176 124.556 1.00 84.03  ?  292  ILE R CA  1 
ATOM 4614 C C   . ILE B 1 316 ? 104.798 109.025 123.375 1.00 84.03  ?  292  ILE R C   1 
ATOM 4615 O O   . ILE B 1 316 ? 104.375 109.100 122.216 1.00 84.03  ?  292  ILE R O   1 
ATOM 4616 C CB  . ILE B 1 316 ? 103.669 110.649 124.973 1.00 84.03  ?  292  ILE R CB  1 
ATOM 4617 C CG1 . ILE B 1 316 ? 102.314 110.850 125.656 1.00 84.03  ?  292  ILE R CG1 1 
ATOM 4618 C CG2 . ILE B 1 316 ? 103.808 111.592 123.786 1.00 84.03  ?  292  ILE R CG2 1 
ATOM 4619 C CD1 . ILE B 1 316 ? 102.115 112.239 126.221 1.00 84.03  ?  292  ILE R CD1 1 
ATOM 4620 N N   . ASN B 1 317 ? 106.076 108.770 123.646 1.00 82.89  ?  293  ASN R N   1 
ATOM 4621 C CA  . ASN B 1 317 ? 107.100 108.684 122.606 1.00 82.89  ?  293  ASN R CA  1 
ATOM 4622 C C   . ASN B 1 317 ? 106.770 107.677 121.507 1.00 82.89  ?  293  ASN R C   1 
ATOM 4623 O O   . ASN B 1 317 ? 106.870 108.044 120.326 1.00 82.89  ?  293  ASN R O   1 
ATOM 4624 C CB  . ASN B 1 317 ? 108.431 108.402 123.325 1.00 82.89  ?  293  ASN R CB  1 
ATOM 4625 C CG  . ASN B 1 317 ? 109.554 107.898 122.411 1.00 82.89  ?  293  ASN R CG  1 
ATOM 4626 O OD1 . ASN B 1 317 ? 109.372 107.578 121.240 1.00 82.89  ?  293  ASN R OD1 1 
ATOM 4627 N ND2 . ASN B 1 317 ? 110.748 107.824 122.985 1.00 82.89  ?  293  ASN R ND2 1 
ATOM 4628 N N   . PRO B 1 318 ? 106.366 106.434 121.790 1.00 85.51  ?  294  PRO R N   1 
ATOM 4629 C CA  . PRO B 1 318 ? 106.143 105.483 120.695 1.00 85.51  ?  294  PRO R CA  1 
ATOM 4630 C C   . PRO B 1 318 ? 104.880 105.740 119.891 1.00 85.51  ?  294  PRO R C   1 
ATOM 4631 O O   . PRO B 1 318 ? 104.482 104.876 119.104 1.00 85.51  ?  294  PRO R O   1 
ATOM 4632 C CB  . PRO B 1 318 ? 106.073 104.123 121.409 1.00 85.51  ?  294  PRO R CB  1 
ATOM 4633 C CG  . PRO B 1 318 ? 105.904 104.407 122.848 1.00 85.51  ?  294  PRO R CG  1 
ATOM 4634 C CD  . PRO B 1 318 ? 105.939 105.874 123.084 1.00 85.51  ?  294  PRO R CD  1 
ATOM 4635 N N   . ILE B 1 319 ? 104.243 106.891 120.068 1.00 87.94  ?  295  ILE R N   1 
ATOM 4636 C CA  . ILE B 1 319 ? 103.127 107.271 119.215 1.00 87.94  ?  295  ILE R CA  1 
ATOM 4637 C C   . ILE B 1 319 ? 103.538 108.351 118.215 1.00 87.94  ?  295  ILE R C   1 
ATOM 4638 O O   . ILE B 1 319 ? 102.994 108.409 117.108 1.00 87.94  ?  295  ILE R O   1 
ATOM 4639 C CB  . ILE B 1 319 ? 101.942 107.727 120.085 1.00 87.94  ?  295  ILE R CB  1 
ATOM 4640 C CG1 . ILE B 1 319 ? 101.374 106.541 120.868 1.00 87.94  ?  295  ILE R CG1 1 
ATOM 4641 C CG2 . ILE B 1 319 ? 100.851 108.376 119.241 1.00 87.94  ?  295  ILE R CG2 1 
ATOM 4642 C CD1 . ILE B 1 319 ? 99.968  106.760 121.393 1.00 87.94  ?  295  ILE R CD1 1 
ATOM 4643 N N   . ILE B 1 320 ? 104.513 109.187 118.565 1.00 85.47  ?  296  ILE R N   1 
ATOM 4644 C CA  . ILE B 1 320 ? 104.887 110.322 117.729 1.00 85.47  ?  296  ILE R CA  1 
ATOM 4645 C C   . ILE B 1 320 ? 105.871 109.881 116.656 1.00 85.47  ?  296  ILE R C   1 
ATOM 4646 O O   . ILE B 1 320 ? 105.583 109.980 115.459 1.00 85.47  ?  296  ILE R O   1 
ATOM 4647 C CB  . ILE B 1 320 ? 105.473 111.464 118.579 1.00 85.47  ?  296  ILE R CB  1 
ATOM 4648 C CG1 . ILE B 1 320 ? 104.350 112.231 119.280 1.00 85.47  ?  296  ILE R CG1 1 
ATOM 4649 C CG2 . ILE B 1 320 ? 106.287 112.412 117.713 1.00 85.47  ?  296  ILE R CG2 1 
ATOM 4650 C CD1 . ILE B 1 320 ? 104.755 113.603 119.780 1.00 85.47  ?  296  ILE R CD1 1 
ATOM 4651 N N   . TYR B 1 321 ? 107.042 109.394 117.069 1.00 79.96  ?  297  TYR R N   1 
ATOM 4652 C CA  . TYR B 1 321 ? 108.069 109.046 116.093 1.00 79.96  ?  297  TYR R CA  1 
ATOM 4653 C C   . TYR B 1 321 ? 107.757 107.732 115.393 1.00 79.96  ?  297  TYR R C   1 
ATOM 4654 O O   . TYR B 1 321 ? 107.981 107.601 114.186 1.00 79.96  ?  297  TYR R O   1 
ATOM 4655 C CB  . TYR B 1 321 ? 109.436 108.990 116.769 1.00 79.96  ?  297  TYR R CB  1 
ATOM 4656 C CG  . TYR B 1 321 ? 110.064 110.349 116.940 1.00 79.96  ?  297  TYR R CG  1 
ATOM 4657 C CD1 . TYR B 1 321 ? 110.716 110.967 115.887 1.00 79.96  ?  297  TYR R CD1 1 
ATOM 4658 C CD2 . TYR B 1 321 ? 109.993 111.019 118.149 1.00 79.96  ?  297  TYR R CD2 1 
ATOM 4659 C CE1 . TYR B 1 321 ? 111.288 112.211 116.035 1.00 79.96  ?  297  TYR R CE1 1 
ATOM 4660 C CE2 . TYR B 1 321 ? 110.561 112.263 118.308 1.00 79.96  ?  297  TYR R CE2 1 
ATOM 4661 C CZ  . TYR B 1 321 ? 111.208 112.855 117.247 1.00 79.96  ?  297  TYR R CZ  1 
ATOM 4662 O OH  . TYR B 1 321 ? 111.778 114.097 117.401 1.00 79.96  ?  297  TYR R OH  1 
ATOM 4663 N N   . ALA B 1 322 ? 107.246 106.754 116.127 1.00 89.68  ?  298  ALA R N   1 
ATOM 4664 C CA  . ALA B 1 322 ? 106.761 105.519 115.542 1.00 89.68  ?  298  ALA R CA  1 
ATOM 4665 C C   . ALA B 1 322 ? 105.240 105.568 115.462 1.00 89.68  ?  298  ALA R C   1 
ATOM 4666 O O   . ALA B 1 322 ? 104.607 106.552 115.851 1.00 89.68  ?  298  ALA R O   1 
ATOM 4667 C CB  . ALA B 1 322 ? 107.242 104.314 116.350 1.00 89.68  ?  298  ALA R CB  1 
ATOM 4668 N N   . PHE B 1 323 ? 104.650 104.501 114.921 1.00 103.29 ?  299  PHE R N   1 
ATOM 4669 C CA  . PHE B 1 323 ? 103.200 104.345 114.853 1.00 103.29 ?  299  PHE R CA  1 
ATOM 4670 C C   . PHE B 1 323 ? 102.535 105.409 113.986 1.00 103.29 ?  299  PHE R C   1 
ATOM 4671 O O   . PHE B 1 323 ? 101.305 105.466 113.909 1.00 103.29 ?  299  PHE R O   1 
ATOM 4672 C CB  . PHE B 1 323 ? 102.594 104.372 116.258 1.00 103.29 ?  299  PHE R CB  1 
ATOM 4673 C CG  . PHE B 1 323 ? 101.635 103.253 116.530 1.00 103.29 ?  299  PHE R CG  1 
ATOM 4674 C CD1 . PHE B 1 323 ? 102.085 101.949 116.643 1.00 103.29 ?  299  PHE R CD1 1 
ATOM 4675 C CD2 . PHE B 1 323 ? 100.281 103.506 116.675 1.00 103.29 ?  299  PHE R CD2 1 
ATOM 4676 C CE1 . PHE B 1 323 ? 101.202 100.917 116.898 1.00 103.29 ?  299  PHE R CE1 1 
ATOM 4677 C CE2 . PHE B 1 323 ? 99.393  102.478 116.928 1.00 103.29 ?  299  PHE R CE2 1 
ATOM 4678 C CZ  . PHE B 1 323 ? 99.854  101.182 117.039 1.00 103.29 ?  299  PHE R CZ  1 
ATOM 4679 N N   . ARG B 1 324 ? 103.330 106.256 113.333 1.00 104.03 ?  300  ARG R N   1 
ATOM 4680 C CA  . ARG B 1 324 ? 102.805 107.301 112.463 1.00 104.03 ?  300  ARG R CA  1 
ATOM 4681 C C   . ARG B 1 324 ? 103.046 107.043 110.988 1.00 104.03 ?  300  ARG R C   1 
ATOM 4682 O O   . ARG B 1 324 ? 102.220 107.442 110.165 1.00 104.03 ?  300  ARG R O   1 
ATOM 4683 C CB  . ARG B 1 324 ? 103.412 108.662 112.829 1.00 104.03 ?  300  ARG R CB  1 
ATOM 4684 C CG  . ARG B 1 324 ? 102.785 109.314 114.048 1.00 104.03 ?  300  ARG R CG  1 
ATOM 4685 C CD  . ARG B 1 324 ? 102.351 110.742 113.750 1.00 104.03 ?  300  ARG R CD  1 
ATOM 4686 N NE  . ARG B 1 324 ? 103.281 111.424 112.858 1.00 104.03 ?  300  ARG R NE  1 
ATOM 4687 C CZ  . ARG B 1 324 ? 104.267 112.212 113.263 1.00 104.03 ?  300  ARG R CZ  1 
ATOM 4688 N NH1 . ARG B 1 324 ? 104.485 112.442 114.548 1.00 104.03 1  300  ARG R NH1 1 
ATOM 4689 N NH2 . ARG B 1 324 ? 105.055 112.784 112.357 1.00 104.03 ?  300  ARG R NH2 1 
ATOM 4690 N N   . ASN B 1 325 ? 104.151 106.395 110.633 1.00 107.58 ?  301  ASN R N   1 
ATOM 4691 C CA  . ASN B 1 325 ? 104.366 106.014 109.246 1.00 107.58 ?  301  ASN R CA  1 
ATOM 4692 C C   . ASN B 1 325 ? 103.339 104.969 108.819 1.00 107.58 ?  301  ASN R C   1 
ATOM 4693 O O   . ASN B 1 325 ? 102.740 104.278 109.647 1.00 107.58 ?  301  ASN R O   1 
ATOM 4694 C CB  . ASN B 1 325 ? 105.824 105.559 109.049 1.00 107.58 ?  301  ASN R CB  1 
ATOM 4695 C CG  . ASN B 1 325 ? 106.095 104.114 109.480 1.00 107.58 ?  301  ASN R CG  1 
ATOM 4696 O OD1 . ASN B 1 325 ? 105.224 103.252 109.484 1.00 107.58 ?  301  ASN R OD1 1 
ATOM 4697 N ND2 . ASN B 1 325 ? 107.343 103.858 109.848 1.00 107.58 ?  301  ASN R ND2 1 
ATOM 4698 N N   . GLN B 1 326 ? 103.120 104.872 107.509 1.00 114.74 ?  302  GLN R N   1 
ATOM 4699 C CA  . GLN B 1 326 ? 101.963 104.142 107.007 1.00 114.74 ?  302  GLN R CA  1 
ATOM 4700 C C   . GLN B 1 326 ? 102.175 102.639 106.894 1.00 114.74 ?  302  GLN R C   1 
ATOM 4701 O O   . GLN B 1 326 ? 101.218 101.884 107.083 1.00 114.74 ?  302  GLN R O   1 
ATOM 4702 C CB  . GLN B 1 326 ? 101.539 104.698 105.645 1.00 114.74 ?  302  GLN R CB  1 
ATOM 4703 C CG  . GLN B 1 326 ? 101.117 106.157 105.684 1.00 114.74 ?  302  GLN R CG  1 
ATOM 4704 C CD  . GLN B 1 326 ? 99.986  106.462 104.723 1.00 114.74 ?  302  GLN R CD  1 
ATOM 4705 O OE1 . GLN B 1 326 ? 99.558  105.601 103.955 1.00 114.74 ?  302  GLN R OE1 1 
ATOM 4706 N NE2 . GLN B 1 326 ? 99.489  107.693 104.766 1.00 114.74 ?  302  GLN R NE2 1 
ATOM 4707 N N   . ASP B 1 327 ? 103.387 102.175 106.580 1.00 113.97 ?  303  ASP R N   1 
ATOM 4708 C CA  . ASP B 1 327 ? 103.583 100.739 106.403 1.00 113.97 ?  303  ASP R CA  1 
ATOM 4709 C C   . ASP B 1 327 ? 103.373 99.992  107.715 1.00 113.97 ?  303  ASP R C   1 
ATOM 4710 O O   . ASP B 1 327 ? 102.857 98.864  107.726 1.00 113.97 ?  303  ASP R O   1 
ATOM 4711 C CB  . ASP B 1 327 ? 104.971 100.457 105.827 1.00 113.97 ?  303  ASP R CB  1 
ATOM 4712 C CG  . ASP B 1 327 ? 106.053 101.299 106.465 1.00 113.97 ?  303  ASP R CG  1 
ATOM 4713 O OD1 . ASP B 1 327 ? 106.024 101.464 107.700 1.00 113.97 ?  303  ASP R OD1 1 
ATOM 4714 O OD2 . ASP B 1 327 ? 106.930 101.799 105.732 1.00 113.97 -1 303  ASP R OD2 1 
ATOM 4715 N N   . VAL B 1 328 ? 103.768 100.605 108.832 1.00 115.84 ?  304  VAL R N   1 
ATOM 4716 C CA  . VAL B 1 328 ? 103.457 100.030 110.136 1.00 115.84 ?  304  VAL R CA  1 
ATOM 4717 C C   . VAL B 1 328 ? 101.949 99.933  110.317 1.00 115.84 ?  304  VAL R C   1 
ATOM 4718 O O   . VAL B 1 328 ? 101.433 98.941  110.845 1.00 115.84 ?  304  VAL R O   1 
ATOM 4719 C CB  . VAL B 1 328 ? 104.123 100.851 111.256 1.00 115.84 ?  304  VAL R CB  1 
ATOM 4720 C CG1 . VAL B 1 328 ? 103.554 100.475 112.613 1.00 115.84 ?  304  VAL R CG1 1 
ATOM 4721 C CG2 . VAL B 1 328 ? 105.630 100.639 111.238 1.00 115.84 ?  304  VAL R CG2 1 
ATOM 4722 N N   . GLN B 1 329 ? 101.215 100.949 109.860 1.00 117.46 ?  305  GLN R N   1 
ATOM 4723 C CA  . GLN B 1 329 ? 99.759  100.888 109.925 1.00 117.46 ?  305  GLN R CA  1 
ATOM 4724 C C   . GLN B 1 329 ? 99.219  99.738  109.084 1.00 117.46 ?  305  GLN R C   1 
ATOM 4725 O O   . GLN B 1 329 ? 98.280  99.046  109.492 1.00 117.46 ?  305  GLN R O   1 
ATOM 4726 C CB  . GLN B 1 329 ? 99.158  102.219 109.473 1.00 117.46 ?  305  GLN R CB  1 
ATOM 4727 C CG  . GLN B 1 329 ? 97.641  102.218 109.378 1.00 117.46 ?  305  GLN R CG  1 
ATOM 4728 C CD  . GLN B 1 329 ? 96.973  102.071 110.730 1.00 117.46 ?  305  GLN R CD  1 
ATOM 4729 O OE1 . GLN B 1 329 ? 97.283  102.801 111.672 1.00 117.46 ?  305  GLN R OE1 1 
ATOM 4730 N NE2 . GLN B 1 329 ? 96.049  101.122 110.833 1.00 117.46 ?  305  GLN R NE2 1 
ATOM 4731 N N   . LYS B 1 330 ? 99.801  99.522  107.901 1.00 118.14 ?  306  LYS R N   1 
ATOM 4732 C CA  . LYS B 1 330 ? 99.345  98.434  107.043 1.00 118.14 ?  306  LYS R CA  1 
ATOM 4733 C C   . LYS B 1 330 ? 99.568  97.079  107.699 1.00 118.14 ?  306  LYS R C   1 
ATOM 4734 O O   . LYS B 1 330 ? 98.675  96.224  107.690 1.00 118.14 ?  306  LYS R O   1 
ATOM 4735 C CB  . LYS B 1 330 ? 100.051 98.489  105.687 1.00 118.14 ?  306  LYS R CB  1 
ATOM 4736 C CG  . LYS B 1 330 ? 100.039 99.851  105.020 1.00 118.14 ?  306  LYS R CG  1 
ATOM 4737 C CD  . LYS B 1 330 ? 101.027 99.903  103.866 1.00 118.14 ?  306  LYS R CD  1 
ATOM 4738 C CE  . LYS B 1 330 ? 101.331 101.335 103.460 1.00 118.14 ?  306  LYS R CE  1 
ATOM 4739 N NZ  . LYS B 1 330 ? 102.259 101.396 102.297 1.00 118.14 1  306  LYS R NZ  1 
ATOM 4740 N N   . VAL B 1 331 ? 100.752 96.859  108.274 1.00 117.13 ?  307  VAL R N   1 
ATOM 4741 C CA  . VAL B 1 331 ? 101.009 95.559  108.891 1.00 117.13 ?  307  VAL R CA  1 
ATOM 4742 C C   . VAL B 1 331 ? 100.156 95.388  110.142 1.00 117.13 ?  307  VAL R C   1 
ATOM 4743 O O   . VAL B 1 331 ? 99.730  94.274  110.470 1.00 117.13 ?  307  VAL R O   1 
ATOM 4744 C CB  . VAL B 1 331 ? 102.509 95.359  109.186 1.00 117.13 ?  307  VAL R CB  1 
ATOM 4745 C CG1 . VAL B 1 331 ? 103.269 95.064  107.899 1.00 117.13 ?  307  VAL R CG1 1 
ATOM 4746 C CG2 . VAL B 1 331 ? 103.095 96.546  109.902 1.00 117.13 ?  307  VAL R CG2 1 
ATOM 4747 N N   . LEU B 1 332 ? 99.886  96.483  110.859 1.00 120.56 ?  308  LEU R N   1 
ATOM 4748 C CA  . LEU B 1 332 ? 98.981  96.399  112.000 1.00 120.56 ?  308  LEU R CA  1 
ATOM 4749 C C   . LEU B 1 332 ? 97.581  95.993  111.564 1.00 120.56 ?  308  LEU R C   1 
ATOM 4750 O O   . LEU B 1 332 ? 96.958  95.122  112.182 1.00 120.56 ?  308  LEU R O   1 
ATOM 4751 C CB  . LEU B 1 332 ? 98.933  97.735  112.741 1.00 120.56 ?  308  LEU R CB  1 
ATOM 4752 C CG  . LEU B 1 332 ? 100.048 98.049  113.736 1.00 120.56 ?  308  LEU R CG  1 
ATOM 4753 C CD1 . LEU B 1 332 ? 100.273 99.547  113.805 1.00 120.56 ?  308  LEU R CD1 1 
ATOM 4754 C CD2 . LEU B 1 332 ? 99.704  97.495  115.109 1.00 120.56 ?  308  LEU R CD2 1 
ATOM 4755 N N   . TRP B 1 333 ? 97.070  96.614  110.499 1.00 120.70 ?  309  TRP R N   1 
ATOM 4756 C CA  . TRP B 1 333 ? 95.740  96.265  110.011 1.00 120.70 ?  309  TRP R CA  1 
ATOM 4757 C C   . TRP B 1 333 ? 95.706  94.824  109.523 1.00 120.70 ?  309  TRP R C   1 
ATOM 4758 O O   . TRP B 1 333 ? 94.710  94.117  109.714 1.00 120.70 ?  309  TRP R O   1 
ATOM 4759 C CB  . TRP B 1 333 ? 95.319  97.225  108.899 1.00 120.70 ?  309  TRP R CB  1 
ATOM 4760 C CG  . TRP B 1 333 ? 93.949  96.975  108.300 1.00 120.70 ?  309  TRP R CG  1 
ATOM 4761 C CD1 . TRP B 1 333 ? 93.568  97.255  107.021 1.00 120.70 ?  309  TRP R CD1 1 
ATOM 4762 C CD2 . TRP B 1 333 ? 92.773  96.467  108.963 1.00 120.70 ?  309  TRP R CD2 1 
ATOM 4763 N NE1 . TRP B 1 333 ? 92.251  96.920  106.831 1.00 120.70 ?  309  TRP R NE1 1 
ATOM 4764 C CE2 . TRP B 1 333 ? 91.739  96.439  108.007 1.00 120.70 ?  309  TRP R CE2 1 
ATOM 4765 C CE3 . TRP B 1 333 ? 92.497  96.025  110.263 1.00 120.70 ?  309  TRP R CE3 1 
ATOM 4766 C CZ2 . TRP B 1 333 ? 90.456  95.984  108.306 1.00 120.70 ?  309  TRP R CZ2 1 
ATOM 4767 C CZ3 . TRP B 1 333 ? 91.225  95.570  110.555 1.00 120.70 ?  309  TRP R CZ3 1 
ATOM 4768 C CH2 . TRP B 1 333 ? 90.221  95.555  109.583 1.00 120.70 ?  309  TRP R CH2 1 
ATOM 4769 N N   . ALA B 1 334 ? 96.788  94.370  108.888 1.00 122.33 ?  310  ALA R N   1 
ATOM 4770 C CA  . ALA B 1 334 ? 96.873  92.969  108.490 1.00 122.33 ?  310  ALA R CA  1 
ATOM 4771 C C   . ALA B 1 334 ? 96.813  92.052  109.704 1.00 122.33 ?  310  ALA R C   1 
ATOM 4772 O O   . ALA B 1 334 ? 96.125  91.025  109.684 1.00 122.33 ?  310  ALA R O   1 
ATOM 4773 C CB  . ALA B 1 334 ? 98.153  92.724  107.692 1.00 122.33 ?  310  ALA R CB  1 
ATOM 4774 N N   . VAL B 1 335 ? 97.531  92.407  110.772 1.00 133.20 ?  311  VAL R N   1 
ATOM 4775 C CA  . VAL B 1 335 ? 97.430  91.652  112.016 1.00 133.20 ?  311  VAL R CA  1 
ATOM 4776 C C   . VAL B 1 335 ? 96.035  91.792  112.611 1.00 133.20 ?  311  VAL R C   1 
ATOM 4777 O O   . VAL B 1 335 ? 95.428  90.806  113.046 1.00 133.20 ?  311  VAL R O   1 
ATOM 4778 C CB  . VAL B 1 335 ? 98.519  92.108  113.005 1.00 133.20 ?  311  VAL R CB  1 
ATOM 4779 C CG1 . VAL B 1 335 ? 98.228  91.581  114.403 1.00 133.20 ?  311  VAL R CG1 1 
ATOM 4780 C CG2 . VAL B 1 335 ? 99.891  91.650  112.533 1.00 133.20 ?  311  VAL R CG2 1 
ATOM 4781 N N   . CYS B 1 336 ? 95.501  93.009  112.630 1.00 134.69 ?  312  CYS R N   1 
ATOM 4782 C CA  . CYS B 1 336 ? 94.178  93.258  113.188 1.00 134.69 ?  312  CYS R CA  1 
ATOM 4783 C C   . CYS B 1 336 ? 93.099  93.135  112.119 1.00 134.69 ?  312  CYS R C   1 
ATOM 4784 O O   . CYS B 1 336 ? 92.647  92.035  111.803 1.00 134.69 ?  312  CYS R O   1 
ATOM 4785 C CB  . CYS B 1 336 ? 94.121  94.642  113.837 1.00 134.69 ?  312  CYS R CB  1 
ATOM 4786 S SG  . CYS B 1 336 ? 95.316  94.893  115.171 1.00 134.69 ?  312  CYS R SG  1 
ATOM 4787 N N   . MET B 1 375 ? 106.401 127.245 100.338 1.00 102.90 ?  1001 MET R N   1 
ATOM 4788 C CA  . MET B 1 375 ? 106.293 128.471 99.558  1.00 102.90 ?  1001 MET R CA  1 
ATOM 4789 C C   . MET B 1 375 ? 106.207 128.130 98.076  1.00 102.90 ?  1001 MET R C   1 
ATOM 4790 O O   . MET B 1 375 ? 105.884 128.987 97.248  1.00 102.90 ?  1001 MET R O   1 
ATOM 4791 C CB  . MET B 1 375 ? 107.472 129.404 99.842  1.00 102.90 ?  1001 MET R CB  1 
ATOM 4792 C CG  . MET B 1 375 ? 108.525 129.454 98.752  1.00 102.90 ?  1001 MET R CG  1 
ATOM 4793 S SD  . MET B 1 375 ? 109.624 130.873 98.917  1.00 102.90 ?  1001 MET R SD  1 
ATOM 4794 C CE  . MET B 1 375 ? 110.148 130.695 100.620 1.00 102.90 ?  1001 MET R CE  1 
ATOM 4795 N N   . ILE B 1 376 ? 106.476 126.872 97.739  1.00 102.82 ?  1002 ILE R N   1 
ATOM 4796 C CA  . ILE B 1 376 ? 106.398 126.385 96.368  1.00 102.82 ?  1002 ILE R CA  1 
ATOM 4797 C C   . ILE B 1 376 ? 105.201 125.457 96.189  1.00 102.82 ?  1002 ILE R C   1 
ATOM 4798 O O   . ILE B 1 376 ? 104.564 125.446 95.135  1.00 102.82 ?  1002 ILE R O   1 
ATOM 4799 C CB  . ILE B 1 376 ? 107.716 125.697 95.953  1.00 102.82 ?  1002 ILE R CB  1 
ATOM 4800 C CG1 . ILE B 1 376 ? 108.851 126.717 96.016  1.00 102.82 ?  1002 ILE R CG1 1 
ATOM 4801 C CG2 . ILE B 1 376 ? 107.606 125.103 94.560  1.00 102.82 ?  1002 ILE R CG2 1 
ATOM 4802 C CD1 . ILE B 1 376 ? 108.505 128.054 95.388  1.00 102.82 ?  1002 ILE R CD1 1 
ATOM 4803 N N   . GLU B 1 377 ? 104.871 124.682 97.218  1.00 111.20 ?  1003 GLU R N   1 
ATOM 4804 C CA  . GLU B 1 377 ? 103.650 123.888 97.235  1.00 111.20 ?  1003 GLU R CA  1 
ATOM 4805 C C   . GLU B 1 377 ? 102.425 124.775 97.048  1.00 111.20 ?  1003 GLU R C   1 
ATOM 4806 O O   . GLU B 1 377 ? 101.538 124.467 96.243  1.00 111.20 ?  1003 GLU R O   1 
ATOM 4807 C CB  . GLU B 1 377 ? 103.555 123.118 98.555  1.00 111.20 ?  1003 GLU R CB  1 
ATOM 4808 C CG  . GLU B 1 377 ? 102.416 122.103 98.701  1.00 111.20 ?  1003 GLU R CG  1 
ATOM 4809 C CD  . GLU B 1 377 ? 101.858 121.570 97.392  1.00 111.20 ?  1003 GLU R CD  1 
ATOM 4810 O OE1 . GLU B 1 377 ? 100.621 121.443 97.305  1.00 111.20 ?  1003 GLU R OE1 1 
ATOM 4811 O OE2 . GLU B 1 377 ? 102.639 121.209 96.484  1.00 111.20 -1 1003 GLU R OE2 1 
ATOM 4812 N N   . GLU B 1 378 ? 102.373 125.881 97.794  1.00 115.63 ?  1004 GLU R N   1 
ATOM 4813 C CA  . GLU B 1 378 ? 101.282 126.839 97.668  1.00 115.63 ?  1004 GLU R CA  1 
ATOM 4814 C C   . GLU B 1 378 ? 101.188 127.427 96.270  1.00 115.63 ?  1004 GLU R C   1 
ATOM 4815 O O   . GLU B 1 378 ? 100.090 127.482 95.708  1.00 115.63 ?  1004 GLU R O   1 
ATOM 4816 C CB  . GLU B 1 378 ? 101.463 127.967 98.689  1.00 115.63 ?  1004 GLU R CB  1 
ATOM 4817 C CG  . GLU B 1 378 ? 100.306 128.970 98.861  1.00 115.63 ?  1004 GLU R CG  1 
ATOM 4818 C CD  . GLU B 1 378 ? 98.930  128.466 98.444  1.00 115.63 ?  1004 GLU R CD  1 
ATOM 4819 O OE1 . GLU B 1 378 ? 98.572  127.312 98.753  1.00 115.63 ?  1004 GLU R OE1 1 
ATOM 4820 O OE2 . GLU B 1 378 ? 98.196  129.243 97.797  1.00 115.63 -1 1004 GLU R OE2 1 
ATOM 4821 N N   . THR B 1 379 ? 102.313 127.853 95.695  1.00 110.62 ?  1005 THR R N   1 
ATOM 4822 C CA  . THR B 1 379 ? 102.293 128.428 94.356  1.00 110.62 ?  1005 THR R CA  1 
ATOM 4823 C C   . THR B 1 379 ? 101.841 127.401 93.327  1.00 110.62 ?  1005 THR R C   1 
ATOM 4824 O O   . THR B 1 379 ? 101.036 127.706 92.439  1.00 110.62 ?  1005 THR R O   1 
ATOM 4825 C CB  . THR B 1 379 ? 103.678 128.972 94.005  1.00 110.62 ?  1005 THR R CB  1 
ATOM 4826 O OG1 . THR B 1 379 ? 103.971 130.102 94.835  1.00 110.62 ?  1005 THR R OG1 1 
ATOM 4827 C CG2 . THR B 1 379 ? 103.734 129.398 92.547  1.00 110.62 ?  1005 THR R CG2 1 
ATOM 4828 N N   . ALA B 1 380 ? 102.337 126.173 93.443  1.00 115.28 ?  1006 ALA R N   1 
ATOM 4829 C CA  . ALA B 1 380 ? 101.989 125.096 92.531  1.00 115.28 ?  1006 ALA R CA  1 
ATOM 4830 C C   . ALA B 1 380 ? 100.520 124.722 92.601  1.00 115.28 ?  1006 ALA R C   1 
ATOM 4831 O O   . ALA B 1 380 ? 99.911  124.458 91.560  1.00 115.28 ?  1006 ALA R O   1 
ATOM 4832 C CB  . ALA B 1 380 ? 102.851 123.864 92.816  1.00 115.28 ?  1006 ALA R CB  1 
ATOM 4833 N N   . LYS B 1 381 ? 99.937  124.690 93.796  1.00 118.26 ?  1007 LYS R N   1 
ATOM 4834 C CA  . LYS B 1 381 ? 98.518  124.376 93.886  1.00 118.26 ?  1007 LYS R CA  1 
ATOM 4835 C C   . LYS B 1 381 ? 97.661  125.565 93.464  1.00 118.26 ?  1007 LYS R C   1 
ATOM 4836 O O   . LYS B 1 381 ? 96.563  125.383 92.930  1.00 118.26 ?  1007 LYS R O   1 
ATOM 4837 C CB  . LYS B 1 381 ? 98.168  123.901 95.297  1.00 118.26 ?  1007 LYS R CB  1 
ATOM 4838 C CG  . LYS B 1 381 ? 98.123  124.981 96.357  1.00 118.26 ?  1007 LYS R CG  1 
ATOM 4839 C CD  . LYS B 1 381 ? 98.499  124.402 97.712  1.00 118.26 ?  1007 LYS R CD  1 
ATOM 4840 C CE  . LYS B 1 381 ? 97.831  123.057 97.952  1.00 118.26 ?  1007 LYS R CE  1 
ATOM 4841 N NZ  . LYS B 1 381 ? 98.156  122.509 99.296  1.00 118.26 1  1007 LYS R NZ  1 
ATOM 4842 N N   . LYS B 1 382 ? 98.152  126.789 93.673  1.00 120.88 ?  1008 LYS R N   1 
ATOM 4843 C CA  . LYS B 1 382 ? 97.443  127.962 93.176  1.00 120.88 ?  1008 LYS R CA  1 
ATOM 4844 C C   . LYS B 1 382 ? 97.369  127.945 91.654  1.00 120.88 ?  1008 LYS R C   1 
ATOM 4845 O O   . LYS B 1 382 ? 96.322  128.229 91.061  1.00 120.88 ?  1008 LYS R O   1 
ATOM 4846 C CB  . LYS B 1 382 ? 98.131  129.237 93.667  1.00 120.88 ?  1008 LYS R CB  1 
ATOM 4847 C CG  . LYS B 1 382 ? 97.710  130.488 92.910  1.00 120.88 ?  1008 LYS R CG  1 
ATOM 4848 C CD  . LYS B 1 382 ? 98.270  131.750 93.543  1.00 120.88 ?  1008 LYS R CD  1 
ATOM 4849 C CE  . LYS B 1 382 ? 98.024  131.782 95.041  1.00 120.88 ?  1008 LYS R CE  1 
ATOM 4850 N NZ  . LYS B 1 382 ? 98.900  132.776 95.719  1.00 120.88 1  1008 LYS R NZ  1 
ATOM 4851 N N   . VAL B 1 383 ? 98.486  127.608 91.005  1.00 122.97 ?  1009 VAL R N   1 
ATOM 4852 C CA  . VAL B 1 383 ? 98.494  127.495 89.549  1.00 122.97 ?  1009 VAL R CA  1 
ATOM 4853 C C   . VAL B 1 383 ? 97.537  126.399 89.100  1.00 122.97 ?  1009 VAL R C   1 
ATOM 4854 O O   . VAL B 1 383 ? 96.787  126.564 88.130  1.00 122.97 ?  1009 VAL R O   1 
ATOM 4855 C CB  . VAL B 1 383 ? 99.926  127.242 89.039  1.00 122.97 ?  1009 VAL R CB  1 
ATOM 4856 C CG1 . VAL B 1 383 ? 99.912  126.869 87.563  1.00 122.97 ?  1009 VAL R CG1 1 
ATOM 4857 C CG2 . VAL B 1 383 ? 100.797 128.467 89.273  1.00 122.97 ?  1009 VAL R CG2 1 
ATOM 4858 N N   . LYS B 1 384 ? 97.544  125.265 89.805  1.00 124.49 ?  1010 LYS R N   1 
ATOM 4859 C CA  . LYS B 1 384 ? 96.679  124.150 89.433  1.00 124.49 ?  1010 LYS R CA  1 
ATOM 4860 C C   . LYS B 1 384 ? 95.207  124.525 89.550  1.00 124.49 ?  1010 LYS R C   1 
ATOM 4861 O O   . LYS B 1 384 ? 94.393  124.142 88.702  1.00 124.49 ?  1010 LYS R O   1 
ATOM 4862 C CB  . LYS B 1 384 ? 96.993  122.932 90.300  1.00 124.49 ?  1010 LYS R CB  1 
ATOM 4863 C CG  . LYS B 1 384 ? 96.230  121.681 89.908  1.00 124.49 ?  1010 LYS R CG  1 
ATOM 4864 C CD  . LYS B 1 384 ? 96.343  121.415 88.417  1.00 124.49 ?  1010 LYS R CD  1 
ATOM 4865 C CE  . LYS B 1 384 ? 95.679  120.102 88.040  1.00 124.49 ?  1010 LYS R CE  1 
ATOM 4866 N NZ  . LYS B 1 384 ? 96.270  118.953 88.778  1.00 124.49 1  1010 LYS R NZ  1 
ATOM 4867 N N   . GLU B 1 385 ? 94.844  125.266 90.599  1.00 124.75 ?  1011 GLU R N   1 
ATOM 4868 C CA  . GLU B 1 385 ? 93.453  125.678 90.758  1.00 124.75 ?  1011 GLU R CA  1 
ATOM 4869 C C   . GLU B 1 385 ? 93.019  126.637 89.657  1.00 124.75 ?  1011 GLU R C   1 
ATOM 4870 O O   . GLU B 1 385 ? 91.854  126.614 89.245  1.00 124.75 ?  1011 GLU R O   1 
ATOM 4871 C CB  . GLU B 1 385 ? 93.240  126.316 92.131  1.00 124.75 ?  1011 GLU R CB  1 
ATOM 4872 C CG  . GLU B 1 385 ? 93.456  125.369 93.300  1.00 124.75 ?  1011 GLU R CG  1 
ATOM 4873 C CD  . GLU B 1 385 ? 93.664  126.100 94.612  1.00 124.75 ?  1011 GLU R CD  1 
ATOM 4874 O OE1 . GLU B 1 385 ? 92.658  126.453 95.263  1.00 124.75 ?  1011 GLU R OE1 1 
ATOM 4875 O OE2 . GLU B 1 385 ? 94.833  126.324 94.993  1.00 124.75 -1 1011 GLU R OE2 1 
ATOM 4876 N N   . LEU B 1 386 ? 93.929  127.478 89.167  1.00 127.36 ?  1012 LEU R N   1 
ATOM 4877 C CA  . LEU B 1 386 ? 93.594  128.407 88.098  1.00 127.36 ?  1012 LEU R CA  1 
ATOM 4878 C C   . LEU B 1 386 ? 93.308  127.707 86.776  1.00 127.36 ?  1012 LEU R C   1 
ATOM 4879 O O   . LEU B 1 386 ? 92.767  128.339 85.862  1.00 127.36 ?  1012 LEU R O   1 
ATOM 4880 C CB  . LEU B 1 386 ? 94.724  129.423 87.913  1.00 127.36 ?  1012 LEU R CB  1 
ATOM 4881 C CG  . LEU B 1 386 ? 94.387  130.691 87.125  1.00 127.36 ?  1012 LEU R CG  1 
ATOM 4882 C CD1 . LEU B 1 386 ? 93.202  131.407 87.753  1.00 127.36 ?  1012 LEU R CD1 1 
ATOM 4883 C CD2 . LEU B 1 386 ? 95.589  131.614 87.043  1.00 127.36 ?  1012 LEU R CD2 1 
ATOM 4884 N N   . GLY B 1 387 ? 93.641  126.424 86.655  1.00 136.27 ?  1013 GLY R N   1 
ATOM 4885 C CA  . GLY B 1 387 ? 93.407  125.679 85.438  1.00 136.27 ?  1013 GLY R CA  1 
ATOM 4886 C C   . GLY B 1 387 ? 94.535  125.715 84.431  1.00 136.27 ?  1013 GLY R C   1 
ATOM 4887 O O   . GLY B 1 387 ? 94.446  125.028 83.405  1.00 136.27 ?  1013 GLY R O   1 
ATOM 4888 N N   . PHE B 1 388 ? 95.588  126.487 84.684  1.00 141.72 ?  1014 PHE R N   1 
ATOM 4889 C CA  . PHE B 1 388 ? 96.734  126.526 83.787  1.00 141.72 ?  1014 PHE R CA  1 
ATOM 4890 C C   . PHE B 1 388 ? 97.473  125.195 83.816  1.00 141.72 ?  1014 PHE R C   1 
ATOM 4891 O O   . PHE B 1 388 ? 97.765  124.659 84.890  1.00 141.72 ?  1014 PHE R O   1 
ATOM 4892 C CB  . PHE B 1 388 ? 97.684  127.658 84.174  1.00 141.72 ?  1014 PHE R CB  1 
ATOM 4893 C CG  . PHE B 1 388 ? 97.210  129.022 83.763  1.00 141.72 ?  1014 PHE R CG  1 
ATOM 4894 C CD1 . PHE B 1 388 ? 96.192  129.169 82.839  1.00 141.72 ?  1014 PHE R CD1 1 
ATOM 4895 C CD2 . PHE B 1 388 ? 97.795  130.158 84.294  1.00 141.72 ?  1014 PHE R CD2 1 
ATOM 4896 C CE1 . PHE B 1 388 ? 95.763  130.425 82.459  1.00 141.72 ?  1014 PHE R CE1 1 
ATOM 4897 C CE2 . PHE B 1 388 ? 97.370  131.414 83.918  1.00 141.72 ?  1014 PHE R CE2 1 
ATOM 4898 C CZ  . PHE B 1 388 ? 96.354  131.549 83.000  1.00 141.72 ?  1014 PHE R CZ  1 
ATOM 4899 N N   . LYS B 1 389 ? 97.773  124.661 82.633  1.00 141.60 ?  1015 LYS R N   1 
ATOM 4900 C CA  . LYS B 1 389 ? 98.554  123.437 82.516  1.00 141.60 ?  1015 LYS R CA  1 
ATOM 4901 C C   . LYS B 1 389 ? 100.011 123.684 82.153  1.00 141.60 ?  1015 LYS R C   1 
ATOM 4902 O O   . LYS B 1 389 ? 100.805 122.738 82.182  1.00 141.60 ?  1015 LYS R O   1 
ATOM 4903 C CB  . LYS B 1 389 ? 97.931  122.497 81.475  1.00 141.60 ?  1015 LYS R CB  1 
ATOM 4904 C CG  . LYS B 1 389 ? 96.685  121.764 81.947  1.00 141.60 ?  1015 LYS R CG  1 
ATOM 4905 C CD  . LYS B 1 389 ? 96.372  120.585 81.036  1.00 141.60 ?  1015 LYS R CD  1 
ATOM 4906 C CE  . LYS B 1 389 ? 95.140  119.826 81.502  1.00 141.60 ?  1015 LYS R CE  1 
ATOM 4907 N NZ  . LYS B 1 389 ? 94.892  118.610 80.676  1.00 141.60 1  1015 LYS R NZ  1 
ATOM 4908 N N   . LYS B 1 390 ? 100.386 124.915 81.811  1.00 140.37 ?  1016 LYS R N   1 
ATOM 4909 C CA  . LYS B 1 390 ? 101.748 125.192 81.383  1.00 140.37 ?  1016 LYS R CA  1 
ATOM 4910 C C   . LYS B 1 390 ? 102.178 126.487 82.058  1.00 140.37 ?  1016 LYS R C   1 
ATOM 4911 O O   . LYS B 1 390 ? 101.453 127.484 82.004  1.00 140.37 ?  1016 LYS R O   1 
ATOM 4912 C CB  . LYS B 1 390 ? 101.815 125.301 79.846  1.00 140.37 ?  1016 LYS R CB  1 
ATOM 4913 C CG  . LYS B 1 390 ? 102.828 126.262 79.182  1.00 140.37 ?  1016 LYS R CG  1 
ATOM 4914 C CD  . LYS B 1 390 ? 104.247 126.146 79.745  1.00 140.37 ?  1016 LYS R CD  1 
ATOM 4915 C CE  . LYS B 1 390 ? 104.693 124.685 79.742  1.00 140.37 ?  1016 LYS R CE  1 
ATOM 4916 N NZ  . LYS B 1 390 ? 106.071 124.469 80.238  1.00 140.37 1  1016 LYS R NZ  1 
ATOM 4917 N N   . ALA B 1 391 ? 103.350 126.468 82.691  1.00 140.77 ?  1017 ALA R N   1 
ATOM 4918 C CA  . ALA B 1 391 ? 103.941 127.647 83.305  1.00 140.77 ?  1017 ALA R CA  1 
ATOM 4919 C C   . ALA B 1 391 ? 105.385 127.780 82.848  1.00 140.77 ?  1017 ALA R C   1 
ATOM 4920 O O   . ALA B 1 391 ? 106.043 126.781 82.549  1.00 140.77 ?  1017 ALA R O   1 
ATOM 4921 C CB  . ALA B 1 391 ? 103.881 127.570 84.836  1.00 140.77 ?  1017 ALA R CB  1 
ATOM 4922 N N   . GLY B 1 392 ? 105.867 129.016 82.777  1.00 145.81 ?  1018 GLY R N   1 
ATOM 4923 C CA  . GLY B 1 392 ? 107.262 129.292 82.494  1.00 145.81 ?  1018 GLY R CA  1 
ATOM 4924 C C   . GLY B 1 392 ? 107.960 129.817 83.734  1.00 145.81 ?  1018 GLY R C   1 
ATOM 4925 O O   . GLY B 1 392 ? 107.336 130.426 84.600  1.00 145.81 ?  1018 GLY R O   1 
ATOM 4926 N N   . LEU B 1 393 ? 109.268 129.577 83.817  1.00 132.56 ?  1019 LEU R N   1 
ATOM 4927 C CA  . LEU B 1 393 ? 110.038 129.911 85.009  1.00 132.56 ?  1019 LEU R CA  1 
ATOM 4928 C C   . LEU B 1 393 ? 111.178 130.863 84.678  1.00 132.56 ?  1019 LEU R C   1 
ATOM 4929 O O   . LEU B 1 393 ? 111.841 130.718 83.648  1.00 132.56 ?  1019 LEU R O   1 
ATOM 4930 C CB  . LEU B 1 393 ? 110.599 128.645 85.662  1.00 132.56 ?  1019 LEU R CB  1 
ATOM 4931 C CG  . LEU B 1 393 ? 111.717 128.795 86.693  1.00 132.56 ?  1019 LEU R CG  1 
ATOM 4932 C CD1 . LEU B 1 393 ? 111.263 129.633 87.874  1.00 132.56 ?  1019 LEU R CD1 1 
ATOM 4933 C CD2 . LEU B 1 393 ? 112.182 127.426 87.152  1.00 132.56 ?  1019 LEU R CD2 1 
ATOM 4934 N N   . LEU B 1 394 ? 111.402 131.838 85.559  1.00 121.72 ?  1020 LEU R N   1 
ATOM 4935 C CA  . LEU B 1 394 ? 112.595 132.676 85.522  1.00 121.72 ?  1020 LEU R CA  1 
ATOM 4936 C C   . LEU B 1 394 ? 113.251 132.611 86.894  1.00 121.72 ?  1020 LEU R C   1 
ATOM 4937 O O   . LEU B 1 394 ? 112.680 133.091 87.878  1.00 121.72 ?  1020 LEU R O   1 
ATOM 4938 C CB  . LEU B 1 394 ? 112.251 134.118 85.156  1.00 121.72 ?  1020 LEU R CB  1 
ATOM 4939 C CG  . LEU B 1 394 ? 111.060 134.365 84.231  1.00 121.72 ?  1020 LEU R CG  1 
ATOM 4940 C CD1 . LEU B 1 394 ? 110.761 135.852 84.152  1.00 121.72 ?  1020 LEU R CD1 1 
ATOM 4941 C CD2 . LEU B 1 394 ? 111.345 133.819 82.846  1.00 121.72 ?  1020 LEU R CD2 1 
ATOM 4942 N N   . ALA B 1 395 ? 114.442 132.026 86.965  1.00 117.43 ?  1021 ALA R N   1 
ATOM 4943 C CA  . ALA B 1 395 ? 115.165 131.908 88.226  1.00 117.43 ?  1021 ALA R CA  1 
ATOM 4944 C C   . ALA B 1 395 ? 116.638 131.662 87.924  1.00 117.43 ?  1021 ALA R C   1 
ATOM 4945 O O   . ALA B 1 395 ? 117.069 131.686 86.768  1.00 117.43 ?  1021 ALA R O   1 
ATOM 4946 C CB  . ALA B 1 395 ? 114.579 130.797 89.100  1.00 117.43 ?  1021 ALA R CB  1 
ATOM 4947 N N   . THR B 1 396 ? 117.412 131.424 88.982  1.00 114.02 ?  1022 THR R N   1 
ATOM 4948 C CA  . THR B 1 396 ? 118.847 131.225 88.841  1.00 114.02 ?  1022 THR R CA  1 
ATOM 4949 C C   . THR B 1 396 ? 119.153 129.849 88.253  1.00 114.02 ?  1022 THR R C   1 
ATOM 4950 O O   . THR B 1 396 ? 118.313 128.945 88.240  1.00 114.02 ?  1022 THR R O   1 
ATOM 4951 C CB  . THR B 1 396 ? 119.550 131.373 90.190  1.00 114.02 ?  1022 THR R CB  1 
ATOM 4952 O OG1 . THR B 1 396 ? 119.075 130.364 91.088  1.00 114.02 ?  1022 THR R OG1 1 
ATOM 4953 C CG2 . THR B 1 396 ? 119.271 132.744 90.786  1.00 114.02 ?  1022 THR R CG2 1 
ATOM 4954 N N   . THR B 1 397 ? 120.387 129.700 87.765  1.00 110.47 ?  1023 THR R N   1 
ATOM 4955 C CA  . THR B 1 397 ? 120.797 128.443 87.147  1.00 110.47 ?  1023 THR R CA  1 
ATOM 4956 C C   . THR B 1 397 ? 120.767 127.296 88.150  1.00 110.47 ?  1023 THR R C   1 
ATOM 4957 O O   . THR B 1 397 ? 120.312 126.189 87.832  1.00 110.47 ?  1023 THR R O   1 
ATOM 4958 C CB  . THR B 1 397 ? 122.191 128.588 86.539  1.00 110.47 ?  1023 THR R CB  1 
ATOM 4959 O OG1 . THR B 1 397 ? 122.189 129.663 85.591  1.00 110.47 ?  1023 THR R OG1 1 
ATOM 4960 C CG2 . THR B 1 397 ? 122.603 127.304 85.835  1.00 110.47 ?  1023 THR R CG2 1 
ATOM 4961 N N   . GLY B 1 398 ? 121.252 127.539 89.366  1.00 106.03 ?  1024 GLY R N   1 
ATOM 4962 C CA  . GLY B 1 398 ? 121.197 126.504 90.381  1.00 106.03 ?  1024 GLY R CA  1 
ATOM 4963 C C   . GLY B 1 398 ? 119.778 126.058 90.662  1.00 106.03 ?  1024 GLY R C   1 
ATOM 4964 O O   . GLY B 1 398 ? 119.509 124.864 90.810  1.00 106.03 ?  1024 GLY R O   1 
ATOM 4965 N N   . THR B 1 399 ? 118.847 127.010 90.719  1.00 110.90 ?  1025 THR R N   1 
ATOM 4966 C CA  . THR B 1 399 ? 117.460 126.674 91.019  1.00 110.90 ?  1025 THR R CA  1 
ATOM 4967 C C   . THR B 1 399 ? 116.851 125.807 89.925  1.00 110.90 ?  1025 THR R C   1 
ATOM 4968 O O   . THR B 1 399 ? 116.193 124.802 90.214  1.00 110.90 ?  1025 THR R O   1 
ATOM 4969 C CB  . THR B 1 399 ? 116.645 127.950 91.215  1.00 110.90 ?  1025 THR R CB  1 
ATOM 4970 O OG1 . THR B 1 399 ? 117.017 128.913 90.223  1.00 110.90 ?  1025 THR R OG1 1 
ATOM 4971 C CG2 . THR B 1 399 ? 116.892 128.529 92.598  1.00 110.90 ?  1025 THR R CG2 1 
ATOM 4972 N N   . ILE B 1 400 ? 117.061 126.176 88.659  1.00 113.00 ?  1026 ILE R N   1 
ATOM 4973 C CA  . ILE B 1 400 ? 116.466 125.395 87.579  1.00 113.00 ?  1026 ILE R CA  1 
ATOM 4974 C C   . ILE B 1 400 ? 117.100 124.014 87.518  1.00 113.00 ?  1026 ILE R C   1 
ATOM 4975 O O   . ILE B 1 400 ? 116.423 123.017 87.241  1.00 113.00 ?  1026 ILE R O   1 
ATOM 4976 C CB  . ILE B 1 400 ? 116.587 126.125 86.229  1.00 113.00 ?  1026 ILE R CB  1 
ATOM 4977 C CG1 . ILE B 1 400 ? 117.987 126.692 86.044  1.00 113.00 ?  1026 ILE R CG1 1 
ATOM 4978 C CG2 . ILE B 1 400 ? 115.566 127.241 86.136  1.00 113.00 ?  1026 ILE R CG2 1 
ATOM 4979 C CD1 . ILE B 1 400 ? 118.114 127.636 84.882  1.00 113.00 ?  1026 ILE R CD1 1 
ATOM 4980 N N   . VAL B 1 401 ? 118.405 123.929 87.774  1.00 113.52 ?  1027 VAL R N   1 
ATOM 4981 C CA  . VAL B 1 401 ? 119.068 122.630 87.762  1.00 113.52 ?  1027 VAL R CA  1 
ATOM 4982 C C   . VAL B 1 401 ? 118.568 121.762 88.910  1.00 113.52 ?  1027 VAL R C   1 
ATOM 4983 O O   . VAL B 1 401 ? 118.425 120.542 88.767  1.00 113.52 ?  1027 VAL R O   1 
ATOM 4984 C CB  . VAL B 1 401 ? 120.595 122.818 87.801  1.00 113.52 ?  1027 VAL R CB  1 
ATOM 4985 C CG1 . VAL B 1 401 ? 121.295 121.510 88.143  1.00 113.52 ?  1027 VAL R CG1 1 
ATOM 4986 C CG2 . VAL B 1 401 ? 121.088 123.358 86.468  1.00 113.52 ?  1027 VAL R CG2 1 
ATOM 4987 N N   . SER B 1 402 ? 118.259 122.381 90.052  1.00 109.89 ?  1028 SER R N   1 
ATOM 4988 C CA  . SER B 1 402 ? 118.036 121.642 91.291  1.00 109.89 ?  1028 SER R CA  1 
ATOM 4989 C C   . SER B 1 402 ? 116.899 120.634 91.197  1.00 109.89 ?  1028 SER R C   1 
ATOM 4990 O O   . SER B 1 402 ? 116.860 119.691 91.993  1.00 109.89 ?  1028 SER R O   1 
ATOM 4991 C CB  . SER B 1 402 ? 117.762 122.621 92.431  1.00 109.89 ?  1028 SER R CB  1 
ATOM 4992 O OG  . SER B 1 402 ? 116.579 123.356 92.185  1.00 109.89 ?  1028 SER R OG  1 
ATOM 4993 N N   . GLY B 1 403 ? 115.977 120.804 90.256  1.00 115.48 ?  1029 GLY R N   1 
ATOM 4994 C CA  . GLY B 1 403 ? 114.916 119.835 90.088  1.00 115.48 ?  1029 GLY R CA  1 
ATOM 4995 C C   . GLY B 1 403 ? 113.770 119.950 91.066  1.00 115.48 ?  1029 GLY R C   1 
ATOM 4996 O O   . GLY B 1 403 ? 112.958 119.023 91.155  1.00 115.48 ?  1029 GLY R O   1 
ATOM 4997 N N   . VAL B 1 404 ? 113.670 121.058 91.801  1.00 116.56 ?  1030 VAL R N   1 
ATOM 4998 C CA  . VAL B 1 404 ? 112.589 121.198 92.770  1.00 116.56 ?  1030 VAL R CA  1 
ATOM 4999 C C   . VAL B 1 404 ? 111.296 121.622 92.084  1.00 116.56 ?  1030 VAL R C   1 
ATOM 5000 O O   . VAL B 1 404 ? 110.231 121.042 92.331  1.00 116.56 ?  1030 VAL R O   1 
ATOM 5001 C CB  . VAL B 1 404 ? 112.996 122.179 93.884  1.00 116.56 ?  1030 VAL R CB  1 
ATOM 5002 C CG1 . VAL B 1 404 ? 113.998 121.528 94.816  1.00 116.56 ?  1030 VAL R CG1 1 
ATOM 5003 C CG2 . VAL B 1 404 ? 113.585 123.445 93.293  1.00 116.56 ?  1030 VAL R CG2 1 
ATOM 5004 N N   . TYR B 1 405 ? 111.363 122.632 91.213  1.00 117.87 ?  1031 TYR R N   1 
ATOM 5005 C CA  . TYR B 1 405 ? 110.145 123.232 90.681  1.00 117.87 ?  1031 TYR R CA  1 
ATOM 5006 C C   . TYR B 1 405 ? 109.376 122.245 89.815  1.00 117.87 ?  1031 TYR R C   1 
ATOM 5007 O O   . TYR B 1 405 ? 108.153 122.099 89.947  1.00 117.87 ?  1031 TYR R O   1 
ATOM 5008 C CB  . TYR B 1 405 ? 110.485 124.485 89.881  1.00 117.87 ?  1031 TYR R CB  1 
ATOM 5009 C CG  . TYR B 1 405 ? 110.402 125.744 90.697  1.00 117.87 ?  1031 TYR R CG  1 
ATOM 5010 C CD1 . TYR B 1 405 ? 110.329 125.685 92.074  1.00 117.87 ?  1031 TYR R CD1 1 
ATOM 5011 C CD2 . TYR B 1 405 ? 110.439 126.989 90.097  1.00 117.87 ?  1031 TYR R CD2 1 
ATOM 5012 C CE1 . TYR B 1 405 ? 110.271 126.826 92.829  1.00 117.87 ?  1031 TYR R CE1 1 
ATOM 5013 C CE2 . TYR B 1 405 ? 110.374 128.142 90.849  1.00 117.87 ?  1031 TYR R CE2 1 
ATOM 5014 C CZ  . TYR B 1 405 ? 110.291 128.055 92.215  1.00 117.87 ?  1031 TYR R CZ  1 
ATOM 5015 O OH  . TYR B 1 405 ? 110.230 129.204 92.969  1.00 117.87 ?  1031 TYR R OH  1 
ATOM 5016 N N   . GLU B 1 406 ? 110.082 121.562 88.912  1.00 122.83 ?  1032 GLU R N   1 
ATOM 5017 C CA  . GLU B 1 406 ? 109.425 120.602 88.034  1.00 122.83 ?  1032 GLU R CA  1 
ATOM 5018 C C   . GLU B 1 406 ? 108.834 119.447 88.827  1.00 122.83 ?  1032 GLU R C   1 
ATOM 5019 O O   . GLU B 1 406 ? 107.729 118.990 88.529  1.00 122.83 ?  1032 GLU R O   1 
ATOM 5020 C CB  . GLU B 1 406 ? 110.402 120.089 86.973  1.00 122.83 ?  1032 GLU R CB  1 
ATOM 5021 C CG  . GLU B 1 406 ? 111.460 121.089 86.504  1.00 122.83 ?  1032 GLU R CG  1 
ATOM 5022 C CD  . GLU B 1 406 ? 112.615 121.241 87.471  1.00 122.83 ?  1032 GLU R CD  1 
ATOM 5023 O OE1 . GLU B 1 406 ? 112.424 120.952 88.667  1.00 122.83 ?  1032 GLU R OE1 1 
ATOM 5024 O OE2 . GLU B 1 406 ? 113.712 121.645 87.033  1.00 122.83 -1 1032 GLU R OE2 1 
ATOM 5025 N N   . LYS B 1 407 ? 109.546 118.969 89.848  1.00 119.53 ?  1033 LYS R N   1 
ATOM 5026 C CA  . LYS B 1 407 ? 109.011 117.891 90.674  1.00 119.53 ?  1033 LYS R CA  1 
ATOM 5027 C C   . LYS B 1 407 ? 107.731 118.330 91.375  1.00 119.53 ?  1033 LYS R C   1 
ATOM 5028 O O   . LYS B 1 407 ? 106.712 117.624 91.344  1.00 119.53 ?  1033 LYS R O   1 
ATOM 5029 C CB  . LYS B 1 407 ? 110.062 117.446 91.693  1.00 119.53 ?  1033 LYS R CB  1 
ATOM 5030 C CG  . LYS B 1 407 ? 109.506 117.098 93.067  1.00 119.53 ?  1033 LYS R CG  1 
ATOM 5031 C CD  . LYS B 1 407 ? 110.526 117.353 94.166  1.00 119.53 ?  1033 LYS R CD  1 
ATOM 5032 C CE  . LYS B 1 407 ? 111.816 116.590 93.924  1.00 119.53 ?  1033 LYS R CE  1 
ATOM 5033 N NZ  . LYS B 1 407 ? 112.766 116.749 95.060  1.00 119.53 1  1033 LYS R NZ  1 
ATOM 5034 N N   . GLU B 1 408 ? 107.756 119.517 91.985  1.00 124.59 ?  1034 GLU R N   1 
ATOM 5035 C CA  . GLU B 1 408 ? 106.589 119.992 92.719  1.00 124.59 ?  1034 GLU R CA  1 
ATOM 5036 C C   . GLU B 1 408 ? 105.396 120.192 91.797  1.00 124.59 ?  1034 GLU R C   1 
ATOM 5037 O O   . GLU B 1 408 ? 104.265 119.844 92.156  1.00 124.59 ?  1034 GLU R O   1 
ATOM 5038 C CB  . GLU B 1 408 ? 106.920 121.291 93.454  1.00 124.59 ?  1034 GLU R CB  1 
ATOM 5039 C CG  . GLU B 1 408 ? 107.928 121.126 94.576  1.00 124.59 ?  1034 GLU R CG  1 
ATOM 5040 C CD  . GLU B 1 408 ? 107.502 120.078 95.587  1.00 124.59 ?  1034 GLU R CD  1 
ATOM 5041 O OE1 . GLU B 1 408 ? 106.315 120.073 95.975  1.00 124.59 ?  1034 GLU R OE1 1 
ATOM 5042 O OE2 . GLU B 1 408 ? 108.353 119.260 95.992  1.00 124.59 -1 1034 GLU R OE2 1 
ATOM 5043 N N   . PHE B 1 409 ? 105.619 120.754 90.608  1.00 124.59 ?  1035 PHE R N   1 
ATOM 5044 C CA  . PHE B 1 409 ? 104.485 121.018 89.731  1.00 124.59 ?  1035 PHE R CA  1 
ATOM 5045 C C   . PHE B 1 409 ? 104.023 119.756 89.012  1.00 124.59 ?  1035 PHE R C   1 
ATOM 5046 O O   . PHE B 1 409 ? 102.854 119.663 88.621  1.00 124.59 ?  1035 PHE R O   1 
ATOM 5047 C CB  . PHE B 1 409 ? 104.833 122.115 88.734  1.00 124.59 ?  1035 PHE R CB  1 
ATOM 5048 C CG  . PHE B 1 409 ? 104.675 123.500 89.288  1.00 124.59 ?  1035 PHE R CG  1 
ATOM 5049 C CD1 . PHE B 1 409 ? 105.537 123.967 90.264  1.00 124.59 ?  1035 PHE R CD1 1 
ATOM 5050 C CD2 . PHE B 1 409 ? 103.657 124.328 88.850  1.00 124.59 ?  1035 PHE R CD2 1 
ATOM 5051 C CE1 . PHE B 1 409 ? 105.402 125.244 90.778  1.00 124.59 ?  1035 PHE R CE1 1 
ATOM 5052 C CE2 . PHE B 1 409 ? 103.514 125.604 89.361  1.00 124.59 ?  1035 PHE R CE2 1 
ATOM 5053 C CZ  . PHE B 1 409 ? 104.390 126.063 90.325  1.00 124.59 ?  1035 PHE R CZ  1 
ATOM 5054 N N   . SER B 1 410 ? 104.914 118.778 88.830  1.00 124.83 ?  1036 SER R N   1 
ATOM 5055 C CA  . SER B 1 410 ? 104.499 117.486 88.300  1.00 124.83 ?  1036 SER R CA  1 
ATOM 5056 C C   . SER B 1 410 ? 103.707 116.704 89.332  1.00 124.83 ?  1036 SER R C   1 
ATOM 5057 O O   . SER B 1 410 ? 102.921 115.820 88.972  1.00 124.83 ?  1036 SER R O   1 
ATOM 5058 C CB  . SER B 1 410 ? 105.721 116.688 87.848  1.00 124.83 ?  1036 SER R CB  1 
ATOM 5059 O OG  . SER B 1 410 ? 106.543 116.357 88.954  1.00 124.83 ?  1036 SER R OG  1 
ATOM 5060 N N   . LYS B 1 411 ? 103.906 117.009 90.617  1.00 125.69 ?  1037 LYS R N   1 
ATOM 5061 C CA  . LYS B 1 411 ? 103.030 116.454 91.641  1.00 125.69 ?  1037 LYS R CA  1 
ATOM 5062 C C   . LYS B 1 411 ? 101.574 116.848 91.416  1.00 125.69 ?  1037 LYS R C   1 
ATOM 5063 O O   . LYS B 1 411 ? 100.673 116.156 91.903  1.00 125.69 ?  1037 LYS R O   1 
ATOM 5064 C CB  . LYS B 1 411 ? 103.483 116.907 93.030  1.00 125.69 ?  1037 LYS R CB  1 
ATOM 5065 C CG  . LYS B 1 411 ? 104.762 116.247 93.518  1.00 125.69 ?  1037 LYS R CG  1 
ATOM 5066 C CD  . LYS B 1 411 ? 105.120 116.708 94.921  1.00 125.69 ?  1037 LYS R CD  1 
ATOM 5067 C CE  . LYS B 1 411 ? 106.412 116.066 95.400  1.00 125.69 ?  1037 LYS R CE  1 
ATOM 5068 N NZ  . LYS B 1 411 ? 106.787 116.520 96.767  1.00 125.69 1  1037 LYS R NZ  1 
ATOM 5069 N N   . TYR B 1 412 ? 101.326 117.940 90.692  1.00 128.79 ?  1038 TYR R N   1 
ATOM 5070 C CA  . TYR B 1 412 ? 99.976  118.382 90.363  1.00 128.79 ?  1038 TYR R CA  1 
ATOM 5071 C C   . TYR B 1 412 ? 99.693  118.348 88.866  1.00 128.79 ?  1038 TYR R C   1 
ATOM 5072 O O   . TYR B 1 412 ? 98.631  118.814 88.437  1.00 128.79 ?  1038 TYR R O   1 
ATOM 5073 C CB  . TYR B 1 412 ? 99.737  119.794 90.904  1.00 128.79 ?  1038 TYR R CB  1 
ATOM 5074 C CG  . TYR B 1 412 ? 99.501  119.841 92.393  1.00 128.79 ?  1038 TYR R CG  1 
ATOM 5075 C CD1 . TYR B 1 412 ? 98.224  119.697 92.918  1.00 128.79 ?  1038 TYR R CD1 1 
ATOM 5076 C CD2 . TYR B 1 412 ? 100.556 120.017 93.273  1.00 128.79 ?  1038 TYR R CD2 1 
ATOM 5077 C CE1 . TYR B 1 412 ? 98.005  119.737 94.279  1.00 128.79 ?  1038 TYR R CE1 1 
ATOM 5078 C CE2 . TYR B 1 412 ? 100.347 120.055 94.633  1.00 128.79 ?  1038 TYR R CE2 1 
ATOM 5079 C CZ  . TYR B 1 412 ? 99.070  119.916 95.133  1.00 128.79 ?  1038 TYR R CZ  1 
ATOM 5080 O OH  . TYR B 1 412 ? 98.860  119.955 96.493  1.00 128.79 ?  1038 TYR R OH  1 
ATOM 5081 N N   . GLY B 1 413 ? 100.608 117.814 88.060  1.00 136.17 ?  1039 GLY R N   1 
ATOM 5082 C CA  . GLY B 1 413 ? 100.390 117.739 86.629  1.00 136.17 ?  1039 GLY R CA  1 
ATOM 5083 C C   . GLY B 1 413 ? 100.603 119.025 85.863  1.00 136.17 ?  1039 GLY R C   1 
ATOM 5084 O O   . GLY B 1 413 ? 100.061 119.170 84.763  1.00 136.17 ?  1039 GLY R O   1 
ATOM 5085 N N   . VAL B 1 414 ? 101.373 119.966 86.405  1.00 137.41 ?  1040 VAL R N   1 
ATOM 5086 C CA  . VAL B 1 414 ? 101.679 121.227 85.738  1.00 137.41 ?  1040 VAL R CA  1 
ATOM 5087 C C   . VAL B 1 414 ? 103.100 121.157 85.196  1.00 137.41 ?  1040 VAL R C   1 
ATOM 5088 O O   . VAL B 1 414 ? 104.007 120.652 85.868  1.00 137.41 ?  1040 VAL R O   1 
ATOM 5089 C CB  . VAL B 1 414 ? 101.509 122.430 86.686  1.00 137.41 ?  1040 VAL R CB  1 
ATOM 5090 C CG1 . VAL B 1 414 ? 101.516 123.730 85.898  1.00 137.41 ?  1040 VAL R CG1 1 
ATOM 5091 C CG2 . VAL B 1 414 ? 100.224 122.296 87.486  1.00 137.41 ?  1040 VAL R CG2 1 
ATOM 5092 N N   . GLU B 1 415 ? 103.292 121.665 83.981  1.00 136.26 ?  1041 GLU R N   1 
ATOM 5093 C CA  . GLU B 1 415 ? 104.561 121.566 83.272  1.00 136.26 ?  1041 GLU R CA  1 
ATOM 5094 C C   . GLU B 1 415 ? 105.266 122.915 83.268  1.00 136.26 ?  1041 GLU R C   1 
ATOM 5095 O O   . GLU B 1 415 ? 104.684 123.923 82.853  1.00 136.26 ?  1041 GLU R O   1 
ATOM 5096 C CB  . GLU B 1 415 ? 104.340 121.080 81.838  1.00 136.26 ?  1041 GLU R CB  1 
ATOM 5097 C CG  . GLU B 1 415 ? 105.546 121.238 80.925  1.00 136.26 ?  1041 GLU R CG  1 
ATOM 5098 C CD  . GLU B 1 415 ? 105.234 120.886 79.484  1.00 136.26 ?  1041 GLU R CD  1 
ATOM 5099 O OE1 . GLU B 1 415 ? 104.867 119.722 79.224  1.00 136.26 ?  1041 GLU R OE1 1 
ATOM 5100 O OE2 . GLU B 1 415 ? 105.353 121.773 78.611  1.00 136.26 -1 1041 GLU R OE2 1 
ATOM 5101 N N   . ILE B 1 416 ? 106.526 122.924 83.703  1.00 125.73 ?  1042 ILE R N   1 
ATOM 5102 C CA  . ILE B 1 416 ? 107.331 124.138 83.796  1.00 125.73 ?  1042 ILE R CA  1 
ATOM 5103 C C   . ILE B 1 416 ? 108.345 124.149 82.665  1.00 125.73 ?  1042 ILE R C   1 
ATOM 5104 O O   . ILE B 1 416 ? 109.052 123.158 82.440  1.00 125.73 ?  1042 ILE R O   1 
ATOM 5105 C CB  . ILE B 1 416 ? 108.041 124.250 85.156  1.00 125.73 ?  1042 ILE R CB  1 
ATOM 5106 C CG1 . ILE B 1 416 ? 107.092 123.974 86.326  1.00 125.73 ?  1042 ILE R CG1 1 
ATOM 5107 C CG2 . ILE B 1 416 ? 108.667 125.625 85.308  1.00 125.73 ?  1042 ILE R CG2 1 
ATOM 5108 C CD1 . ILE B 1 416 ? 105.723 124.587 86.171  1.00 125.73 ?  1042 ILE R CD1 1 
ATOM 5109 N N   . MET B 1 417 ? 108.421 125.272 81.962  1.00 128.12 ?  1043 MET R N   1 
ATOM 5110 C CA  . MET B 1 417 ? 109.367 125.466 80.875  1.00 128.12 ?  1043 MET R CA  1 
ATOM 5111 C C   . MET B 1 417 ? 110.446 126.437 81.329  1.00 128.12 ?  1043 MET R C   1 
ATOM 5112 O O   . MET B 1 417 ? 110.142 127.498 81.894  1.00 128.12 ?  1043 MET R O   1 
ATOM 5113 C CB  . MET B 1 417 ? 108.664 126.000 79.623  1.00 128.12 ?  1043 MET R CB  1 
ATOM 5114 C CG  . MET B 1 417 ? 109.528 126.248 78.377  1.00 128.12 ?  1043 MET R CG  1 
ATOM 5115 S SD  . MET B 1 417 ? 111.114 125.412 78.112  1.00 128.12 ?  1043 MET R SD  1 
ATOM 5116 C CE  . MET B 1 417 ? 110.777 123.684 78.461  1.00 128.12 ?  1043 MET R CE  1 
ATOM 5117 N N   . THR B 1 418 ? 111.699 126.070 81.083  1.00 131.07 ?  1044 THR R N   1 
ATOM 5118 C CA  . THR B 1 418 ? 112.824 126.928 81.382  1.00 131.07 ?  1044 THR R CA  1 
ATOM 5119 C C   . THR B 1 418 ? 113.521 127.340 80.093  1.00 131.07 ?  1044 THR R C   1 
ATOM 5120 O O   . THR B 1 418 ? 113.673 126.518 79.184  1.00 131.07 ?  1044 THR R O   1 
ATOM 5121 C CB  . THR B 1 418 ? 113.830 126.225 82.305  1.00 131.07 ?  1044 THR R CB  1 
ATOM 5122 O OG1 . THR B 1 418 ? 114.271 125.005 81.694  1.00 131.07 ?  1044 THR R OG1 1 
ATOM 5123 C CG2 . THR B 1 418 ? 113.187 125.912 83.646  1.00 131.07 ?  1044 THR R CG2 1 
ATOM 5124 N N   . PRO B 1 419 ? 113.966 128.589 79.988  1.00 131.84 ?  1045 PRO R N   1 
ATOM 5125 C CA  . PRO B 1 419 ? 114.605 129.054 78.751  1.00 131.84 ?  1045 PRO R CA  1 
ATOM 5126 C C   . PRO B 1 419 ? 115.852 128.247 78.421  1.00 131.84 ?  1045 PRO R C   1 
ATOM 5127 O O   . PRO B 1 419 ? 116.383 127.493 79.239  1.00 131.84 ?  1045 PRO R O   1 
ATOM 5128 C CB  . PRO B 1 419 ? 114.944 130.516 79.060  1.00 131.84 ?  1045 PRO R CB  1 
ATOM 5129 C CG  . PRO B 1 419 ? 113.978 130.905 80.131  1.00 131.84 ?  1045 PRO R CG  1 
ATOM 5130 C CD  . PRO B 1 419 ? 113.799 129.675 80.967  1.00 131.84 ?  1045 PRO R CD  1 
ATOM 5131 N N   . THR B 1 420 ? 116.310 128.395 77.181  1.00 129.40 ?  1046 THR R N   1 
ATOM 5132 C CA  . THR B 1 420 ? 117.485 127.663 76.739  1.00 129.40 ?  1046 THR R CA  1 
ATOM 5133 C C   . THR B 1 420 ? 118.740 128.233 77.389  1.00 129.40 ?  1046 THR R C   1 
ATOM 5134 O O   . THR B 1 420 ? 118.747 129.347 77.919  1.00 129.40 ?  1046 THR R O   1 
ATOM 5135 C CB  . THR B 1 420 ? 117.618 127.707 75.218  1.00 129.40 ?  1046 THR R CB  1 
ATOM 5136 O OG1 . THR B 1 420 ? 118.022 129.018 74.809  1.00 129.40 ?  1046 THR R OG1 1 
ATOM 5137 C CG2 . THR B 1 420 ? 116.293 127.364 74.559  1.00 129.40 ?  1046 THR R CG2 1 
ATOM 5138 N N   . GLU B 1 421 ? 119.821 127.450 77.317  1.00 131.47 ?  1047 GLU R N   1 
ATOM 5139 C CA  . GLU B 1 421 ? 121.019 127.739 78.101  1.00 131.47 ?  1047 GLU R CA  1 
ATOM 5140 C C   . GLU B 1 421 ? 121.542 129.144 77.832  1.00 131.47 ?  1047 GLU R C   1 
ATOM 5141 O O   . GLU B 1 421 ? 121.977 129.837 78.759  1.00 131.47 ?  1047 GLU R O   1 
ATOM 5142 C CB  . GLU B 1 421 ? 122.114 126.702 77.820  1.00 131.47 ?  1047 GLU R CB  1 
ATOM 5143 C CG  . GLU B 1 421 ? 122.610 126.545 76.363  1.00 131.47 ?  1047 GLU R CG  1 
ATOM 5144 C CD  . GLU B 1 421 ? 121.519 126.374 75.314  1.00 131.47 ?  1047 GLU R CD  1 
ATOM 5145 O OE1 . GLU B 1 421 ? 120.377 126.013 75.669  1.00 131.47 ?  1047 GLU R OE1 1 
ATOM 5146 O OE2 . GLU B 1 421 ? 121.807 126.609 74.122  1.00 131.47 -1 1047 GLU R OE2 1 
ATOM 5147 N N   . ASP B 1 422 ? 121.516 129.583 76.574  1.00 135.74 ?  1048 ASP R N   1 
ATOM 5148 C CA  . ASP B 1 422 ? 121.932 130.949 76.275  1.00 135.74 ?  1048 ASP R CA  1 
ATOM 5149 C C   . ASP B 1 422 ? 121.009 131.959 76.945  1.00 135.74 ?  1048 ASP R C   1 
ATOM 5150 O O   . ASP B 1 422 ? 121.470 132.927 77.561  1.00 135.74 ?  1048 ASP R O   1 
ATOM 5151 C CB  . ASP B 1 422 ? 121.968 131.169 74.763  1.00 135.74 ?  1048 ASP R CB  1 
ATOM 5152 C CG  . ASP B 1 422 ? 122.790 132.380 74.370  1.00 135.74 ?  1048 ASP R CG  1 
ATOM 5153 O OD1 . ASP B 1 422 ? 124.021 132.356 74.579  1.00 135.74 ?  1048 ASP R OD1 1 
ATOM 5154 O OD2 . ASP B 1 422 ? 122.206 133.355 73.853  1.00 135.74 -1 1048 ASP R OD2 1 
ATOM 5155 N N   . GLU B 1 423 ? 119.698 131.740 76.852  1.00 138.30 ?  1049 GLU R N   1 
ATOM 5156 C CA  . GLU B 1 423 ? 118.771 132.627 77.542  1.00 138.30 ?  1049 GLU R CA  1 
ATOM 5157 C C   . GLU B 1 423 ? 118.834 132.441 79.052  1.00 138.30 ?  1049 GLU R C   1 
ATOM 5158 O O   . GLU B 1 423 ? 118.552 133.384 79.798  1.00 138.30 ?  1049 GLU R O   1 
ATOM 5159 C CB  . GLU B 1 423 ? 117.353 132.419 77.012  1.00 138.30 ?  1049 GLU R CB  1 
ATOM 5160 C CG  . GLU B 1 423 ? 117.314 131.952 75.564  1.00 138.30 ?  1049 GLU R CG  1 
ATOM 5161 C CD  . GLU B 1 423 ? 116.014 131.268 75.190  1.00 138.30 ?  1049 GLU R CD  1 
ATOM 5162 O OE1 . GLU B 1 423 ? 115.606 130.330 75.904  1.00 138.30 ?  1049 GLU R OE1 1 
ATOM 5163 O OE2 . GLU B 1 423 ? 115.401 131.669 74.178  1.00 138.30 -1 1049 GLU R OE2 1 
ATOM 5164 N N   . GLN B 1 424 ? 119.221 131.253 79.527  1.00 132.70 ?  1050 GLN R N   1 
ATOM 5165 C CA  . GLN B 1 424 ? 119.487 131.101 80.955  1.00 132.70 ?  1050 GLN R CA  1 
ATOM 5166 C C   . GLN B 1 424 ? 120.631 131.997 81.398  1.00 132.70 ?  1050 GLN R C   1 
ATOM 5167 O O   . GLN B 1 424 ? 120.546 132.654 82.439  1.00 132.70 ?  1050 GLN R O   1 
ATOM 5168 C CB  . GLN B 1 424 ? 119.803 129.646 81.300  1.00 132.70 ?  1050 GLN R CB  1 
ATOM 5169 C CG  . GLN B 1 424 ? 118.734 128.645 80.935  1.00 132.70 ?  1050 GLN R CG  1 
ATOM 5170 C CD  . GLN B 1 424 ? 117.456 128.821 81.730  1.00 132.70 ?  1050 GLN R CD  1 
ATOM 5171 O OE1 . GLN B 1 424 ? 117.340 129.711 82.572  1.00 132.70 ?  1050 GLN R OE1 1 
ATOM 5172 N NE2 . GLN B 1 424 ? 116.490 127.953 81.476  1.00 132.70 ?  1050 GLN R NE2 1 
ATOM 5173 N N   . LYS B 1 425 ? 121.716 132.033 80.624  1.00 142.34 ?  1051 LYS R N   1 
ATOM 5174 C CA  . LYS B 1 425 ? 122.823 132.925 80.951  1.00 142.34 ?  1051 LYS R CA  1 
ATOM 5175 C C   . LYS B 1 425 ? 122.395 134.384 80.850  1.00 142.34 ?  1051 LYS R C   1 
ATOM 5176 O O   . LYS B 1 425 ? 122.844 135.231 81.633  1.00 142.34 ?  1051 LYS R O   1 
ATOM 5177 C CB  . LYS B 1 425 ? 124.011 132.635 80.034  1.00 142.34 ?  1051 LYS R CB  1 
ATOM 5178 C CG  . LYS B 1 425 ? 125.285 133.384 80.396  1.00 142.34 ?  1051 LYS R CG  1 
ATOM 5179 C CD  . LYS B 1 425 ? 125.552 134.516 79.422  1.00 142.34 ?  1051 LYS R CD  1 
ATOM 5180 C CE  . LYS B 1 425 ? 125.800 133.985 78.020  1.00 142.34 ?  1051 LYS R CE  1 
ATOM 5181 N NZ  . LYS B 1 425 ? 125.972 135.081 77.028  1.00 142.34 1  1051 LYS R NZ  1 
ATOM 5182 N N   . ASP B 1 426 ? 121.533 134.696 79.881  1.00 144.12 ?  1052 ASP R N   1 
ATOM 5183 C CA  . ASP B 1 426 ? 121.003 136.051 79.775  1.00 144.12 ?  1052 ASP R CA  1 
ATOM 5184 C C   . ASP B 1 426 ? 120.220 136.433 81.027  1.00 144.12 ?  1052 ASP R C   1 
ATOM 5185 O O   . ASP B 1 426 ? 120.358 137.549 81.538  1.00 144.12 ?  1052 ASP R O   1 
ATOM 5186 C CB  . ASP B 1 426 ? 120.129 136.176 78.525  1.00 144.12 ?  1052 ASP R CB  1 
ATOM 5187 C CG  . ASP B 1 426 ? 120.947 136.327 77.256  1.00 144.12 ?  1052 ASP R CG  1 
ATOM 5188 O OD1 . ASP B 1 426 ? 122.191 136.260 77.337  1.00 144.12 ?  1052 ASP R OD1 1 
ATOM 5189 O OD2 . ASP B 1 426 ? 120.344 136.506 76.178  1.00 144.12 -1 1052 ASP R OD2 1 
ATOM 5190 N N   . VAL B 1 427 ? 119.398 135.515 81.539  1.00 145.48 ?  1053 VAL R N   1 
ATOM 5191 C CA  . VAL B 1 427 ? 118.675 135.766 82.785  1.00 145.48 ?  1053 VAL R CA  1 
ATOM 5192 C C   . VAL B 1 427 ? 119.651 135.873 83.950  1.00 145.48 ?  1053 VAL R C   1 
ATOM 5193 O O   . VAL B 1 427 ? 119.448 136.658 84.883  1.00 145.48 ?  1053 VAL R O   1 
ATOM 5194 C CB  . VAL B 1 427 ? 117.619 134.668 83.021  1.00 145.48 ?  1053 VAL R CB  1 
ATOM 5195 C CG1 . VAL B 1 427 ? 117.058 134.739 84.435  1.00 145.48 ?  1053 VAL R CG1 1 
ATOM 5196 C CG2 . VAL B 1 427 ? 116.505 134.782 81.990  1.00 145.48 ?  1053 VAL R CG2 1 
ATOM 5197 N N   . MET B 1 428 ? 120.719 135.077 83.917  1.00 145.90 ?  1054 MET R N   1 
ATOM 5198 C CA  . MET B 1 428 ? 121.762 135.159 84.933  1.00 145.90 ?  1054 MET R CA  1 
ATOM 5199 C C   . MET B 1 428 ? 122.321 136.573 85.010  1.00 145.90 ?  1054 MET R C   1 
ATOM 5200 O O   . MET B 1 428 ? 122.391 137.178 86.090  1.00 145.90 ?  1054 MET R O   1 
ATOM 5201 C CB  . MET B 1 428 ? 122.859 134.146 84.587  1.00 145.90 ?  1054 MET R CB  1 
ATOM 5202 C CG  . MET B 1 428 ? 124.149 134.190 85.389  1.00 145.90 ?  1054 MET R CG  1 
ATOM 5203 S SD  . MET B 1 428 ? 123.958 134.611 87.114  1.00 145.90 ?  1054 MET R SD  1 
ATOM 5204 C CE  . MET B 1 428 ? 123.371 133.058 87.782  1.00 145.90 ?  1054 MET R CE  1 
ATOM 5205 N N   . ARG B 1 429 ? 122.697 137.124 83.856  1.00 147.80 ?  1055 ARG R N   1 
ATOM 5206 C CA  . ARG B 1 429 ? 123.176 138.501 83.809  1.00 147.80 ?  1055 ARG R CA  1 
ATOM 5207 C C   . ARG B 1 429 ? 122.099 139.480 84.257  1.00 147.80 ?  1055 ARG R C   1 
ATOM 5208 O O   . ARG B 1 429 ? 122.363 140.376 85.065  1.00 147.80 ?  1055 ARG R O   1 
ATOM 5209 C CB  . ARG B 1 429 ? 123.651 138.844 82.400  1.00 147.80 ?  1055 ARG R CB  1 
ATOM 5210 C CG  . ARG B 1 429 ? 124.493 137.776 81.747  1.00 147.80 ?  1055 ARG R CG  1 
ATOM 5211 C CD  . ARG B 1 429 ? 124.246 137.731 80.250  1.00 147.80 ?  1055 ARG R CD  1 
ATOM 5212 N NE  . ARG B 1 429 ? 125.065 138.692 79.519  1.00 147.80 ?  1055 ARG R NE  1 
ATOM 5213 C CZ  . ARG B 1 429 ? 124.981 138.898 78.211  1.00 147.80 ?  1055 ARG R CZ  1 
ATOM 5214 N NH1 . ARG B 1 429 ? 124.123 138.227 77.462  1.00 147.80 1  1055 ARG R NH1 1 
ATOM 5215 N NH2 . ARG B 1 429 ? 125.780 139.796 77.639  1.00 147.80 ?  1055 ARG R NH2 1 
ATOM 5216 N N   . GLY B 1 430 ? 120.872 139.308 83.763  1.00 153.71 ?  1056 GLY R N   1 
ATOM 5217 C CA  . GLY B 1 430 ? 119.818 140.254 84.088  1.00 153.71 ?  1056 GLY R CA  1 
ATOM 5218 C C   . GLY B 1 430 ? 119.528 140.316 85.573  1.00 153.71 ?  1056 GLY R C   1 
ATOM 5219 O O   . GLY B 1 430 ? 119.204 141.378 86.110  1.00 153.71 ?  1056 GLY R O   1 
ATOM 5220 N N   . ILE B 1 431 ? 119.642 139.180 86.259  1.00 156.21 ?  1057 ILE R N   1 
ATOM 5221 C CA  . ILE B 1 431 ? 119.429 139.169 87.701  1.00 156.21 ?  1057 ILE R CA  1 
ATOM 5222 C C   . ILE B 1 431 ? 120.630 139.766 88.422  1.00 156.21 ?  1057 ILE R C   1 
ATOM 5223 O O   . ILE B 1 431 ? 120.490 140.714 89.202  1.00 156.21 ?  1057 ILE R O   1 
ATOM 5224 C CB  . ILE B 1 431 ? 119.119 137.745 88.195  1.00 156.21 ?  1057 ILE R CB  1 
ATOM 5225 C CG1 . ILE B 1 431 ? 117.728 137.313 87.722  1.00 156.21 ?  1057 ILE R CG1 1 
ATOM 5226 C CG2 . ILE B 1 431 ? 119.242 137.663 89.708  1.00 156.21 ?  1057 ILE R CG2 1 
ATOM 5227 C CD1 . ILE B 1 431 ? 117.445 135.844 87.901  1.00 156.21 ?  1057 ILE R CD1 1 
ATOM 5228 N N   . TYR B 1 432 ? 121.828 139.236 88.168  1.00 155.37 ?  1058 TYR R N   1 
ATOM 5229 C CA  . TYR B 1 432 ? 123.010 139.654 88.920  1.00 155.37 ?  1058 TYR R CA  1 
ATOM 5230 C C   . TYR B 1 432 ? 123.738 140.832 88.278  1.00 155.37 ?  1058 TYR R C   1 
ATOM 5231 O O   . TYR B 1 432 ? 123.920 141.869 88.923  1.00 155.37 ?  1058 TYR R O   1 
ATOM 5232 C CB  . TYR B 1 432 ? 123.947 138.457 89.118  1.00 155.37 ?  1058 TYR R CB  1 
ATOM 5233 C CG  . TYR B 1 432 ? 123.364 137.410 90.042  1.00 155.37 ?  1058 TYR R CG  1 
ATOM 5234 C CD1 . TYR B 1 432 ? 123.504 137.511 91.416  1.00 155.37 ?  1058 TYR R CD1 1 
ATOM 5235 C CD2 . TYR B 1 432 ? 122.611 136.367 89.544  1.00 155.37 ?  1058 TYR R CD2 1 
ATOM 5236 C CE1 . TYR B 1 432 ? 122.955 136.564 92.271  1.00 155.37 ?  1058 TYR R CE1 1 
ATOM 5237 C CE2 . TYR B 1 432 ? 122.055 135.413 90.379  1.00 155.37 ?  1058 TYR R CE2 1 
ATOM 5238 C CZ  . TYR B 1 432 ? 122.222 135.523 91.750  1.00 155.37 ?  1058 TYR R CZ  1 
ATOM 5239 O OH  . TYR B 1 432 ? 121.668 134.573 92.582  1.00 155.37 ?  1058 TYR R OH  1 
ATOM 5240 N N   . GLU B 1 433 ? 124.169 140.693 87.022  1.00 160.33 ?  1059 GLU R N   1 
ATOM 5241 C CA  . GLU B 1 433 ? 124.793 141.819 86.332  1.00 160.33 ?  1059 GLU R CA  1 
ATOM 5242 C C   . GLU B 1 433 ? 123.805 142.950 86.060  1.00 160.33 ?  1059 GLU R C   1 
ATOM 5243 O O   . GLU B 1 433 ? 124.231 144.066 85.737  1.00 160.33 ?  1059 GLU R O   1 
ATOM 5244 C CB  . GLU B 1 433 ? 125.428 141.343 85.018  1.00 160.33 ?  1059 GLU R CB  1 
ATOM 5245 C CG  . GLU B 1 433 ? 126.358 142.349 84.346  1.00 160.33 ?  1059 GLU R CG  1 
ATOM 5246 C CD  . GLU B 1 433 ? 126.673 141.990 82.906  1.00 160.33 ?  1059 GLU R CD  1 
ATOM 5247 O OE1 . GLU B 1 433 ? 126.285 140.889 82.461  1.00 160.33 ?  1059 GLU R OE1 1 
ATOM 5248 O OE2 . GLU B 1 433 ? 127.320 142.812 82.221  1.00 160.33 -1 1059 GLU R OE2 1 
ATOM 5249 N N   . GLY B 1 434 ? 122.508 142.693 86.212  1.00 161.59 ?  1060 GLY R N   1 
ATOM 5250 C CA  . GLY B 1 434 ? 121.475 143.675 85.958  1.00 161.59 ?  1060 GLY R CA  1 
ATOM 5251 C C   . GLY B 1 434 ? 120.927 144.306 87.222  1.00 161.59 ?  1060 GLY R C   1 
ATOM 5252 O O   . GLY B 1 434 ? 121.499 145.268 87.742  1.00 161.59 ?  1060 GLY R O   1 
ATOM 5253 N N   . VAL B 1 435 ? 119.802 143.777 87.710  1.00 160.72 ?  1061 VAL R N   1 
ATOM 5254 C CA  . VAL B 1 435 ? 119.124 144.368 88.863  1.00 160.72 ?  1061 VAL R CA  1 
ATOM 5255 C C   . VAL B 1 435 ? 120.049 144.406 90.075  1.00 160.72 ?  1061 VAL R C   1 
ATOM 5256 O O   . VAL B 1 435 ? 120.119 145.412 90.791  1.00 160.72 ?  1061 VAL R O   1 
ATOM 5257 C CB  . VAL B 1 435 ? 117.827 143.599 89.172  1.00 160.72 ?  1061 VAL R CB  1 
ATOM 5258 C CG1 . VAL B 1 435 ? 117.040 144.302 90.267  1.00 160.72 ?  1061 VAL R CG1 1 
ATOM 5259 C CG2 . VAL B 1 435 ? 116.986 143.450 87.914  1.00 160.72 ?  1061 VAL R CG2 1 
ATOM 5260 N N   . LYS B 1 436 ? 120.766 143.310 90.330  1.00 159.10 ?  1062 LYS R N   1 
ATOM 5261 C CA  . LYS B 1 436 ? 121.608 143.253 91.521  1.00 159.10 ?  1062 LYS R CA  1 
ATOM 5262 C C   . LYS B 1 436 ? 122.807 144.189 91.411  1.00 159.10 ?  1062 LYS R C   1 
ATOM 5263 O O   . LYS B 1 436 ? 123.215 144.800 92.405  1.00 159.10 ?  1062 LYS R O   1 
ATOM 5264 C CB  . LYS B 1 436 ? 122.073 141.821 91.775  1.00 159.10 ?  1062 LYS R CB  1 
ATOM 5265 C CG  . LYS B 1 436 ? 122.564 141.589 93.195  1.00 159.10 ?  1062 LYS R CG  1 
ATOM 5266 C CD  . LYS B 1 436 ? 122.888 140.129 93.437  1.00 159.10 ?  1062 LYS R CD  1 
ATOM 5267 C CE  . LYS B 1 436 ? 123.109 139.836 94.911  1.00 159.10 ?  1062 LYS R CE  1 
ATOM 5268 N NZ  . LYS B 1 436 ? 121.883 140.085 95.715  1.00 159.10 1  1062 LYS R NZ  1 
ATOM 5269 N N   . ALA B 1 437 ? 123.384 144.319 90.216  1.00 162.02 ?  1063 ALA R N   1 
ATOM 5270 C CA  . ALA B 1 437 ? 124.590 145.121 90.046  1.00 162.02 ?  1063 ALA R CA  1 
ATOM 5271 C C   . ALA B 1 437 ? 124.315 146.618 89.983  1.00 162.02 ?  1063 ALA R C   1 
ATOM 5272 O O   . ALA B 1 437 ? 125.269 147.402 89.940  1.00 162.02 ?  1063 ALA R O   1 
ATOM 5273 C CB  . ALA B 1 437 ? 125.338 144.693 88.781  1.00 162.02 ?  1063 ALA R CB  1 
ATOM 5274 N N   . GLY B 1 438 ? 123.050 147.032 89.976  1.00 164.72 ?  1064 GLY R N   1 
ATOM 5275 C CA  . GLY B 1 438 ? 122.692 148.428 89.864  1.00 164.72 ?  1064 GLY R CA  1 
ATOM 5276 C C   . GLY B 1 438 ? 122.336 148.876 88.464  1.00 164.72 ?  1064 GLY R C   1 
ATOM 5277 O O   . GLY B 1 438 ? 121.736 149.948 88.309  1.00 164.72 ?  1064 GLY R O   1 
ATOM 5278 N N   . ASN B 1 439 ? 122.687 148.093 87.443  1.00 163.35 ?  1065 ASN R N   1 
ATOM 5279 C CA  . ASN B 1 439 ? 122.287 148.374 86.065  1.00 163.35 ?  1065 ASN R CA  1 
ATOM 5280 C C   . ASN B 1 439 ? 120.883 147.812 85.843  1.00 163.35 ?  1065 ASN R C   1 
ATOM 5281 O O   . ASN B 1 439 ? 120.674 146.774 85.210  1.00 163.35 ?  1065 ASN R O   1 
ATOM 5282 C CB  . ASN B 1 439 ? 123.296 147.791 85.085  1.00 163.35 ?  1065 ASN R CB  1 
ATOM 5283 C CG  . ASN B 1 439 ? 123.179 148.392 83.697  1.00 163.35 ?  1065 ASN R CG  1 
ATOM 5284 O OD1 . ASN B 1 439 ? 122.182 149.033 83.366  1.00 163.35 ?  1065 ASN R OD1 1 
ATOM 5285 N ND2 . ASN B 1 439 ? 124.203 148.186 82.877  1.00 163.35 ?  1065 ASN R ND2 1 
ATOM 5286 N N   . LEU B 1 440 ? 119.902 148.530 86.395  1.00 159.05 ?  1066 LEU R N   1 
ATOM 5287 C CA  . LEU B 1 440 ? 118.520 148.065 86.351  1.00 159.05 ?  1066 LEU R CA  1 
ATOM 5288 C C   . LEU B 1 440 ? 118.002 147.964 84.923  1.00 159.05 ?  1066 LEU R C   1 
ATOM 5289 O O   . LEU B 1 440 ? 117.202 147.073 84.618  1.00 159.05 ?  1066 LEU R O   1 
ATOM 5290 C CB  . LEU B 1 440 ? 117.631 149.000 87.170  1.00 159.05 ?  1066 LEU R CB  1 
ATOM 5291 C CG  . LEU B 1 440 ? 117.940 149.110 88.664  1.00 159.05 ?  1066 LEU R CG  1 
ATOM 5292 C CD1 . LEU B 1 440 ? 117.164 150.259 89.288  1.00 159.05 ?  1066 LEU R CD1 1 
ATOM 5293 C CD2 . LEU B 1 440 ? 117.632 147.805 89.377  1.00 159.05 ?  1066 LEU R CD2 1 
ATOM 5294 N N   . LYS B 1 441 ? 118.443 148.866 84.042  1.00 156.31 ?  1067 LYS R N   1 
ATOM 5295 C CA  . LYS B 1 441 ? 117.962 148.868 82.663  1.00 156.31 ?  1067 LYS R CA  1 
ATOM 5296 C C   . LYS B 1 441 ? 118.303 147.563 81.955  1.00 156.31 ?  1067 LYS R C   1 
ATOM 5297 O O   . LYS B 1 441 ? 117.450 146.958 81.296  1.00 156.31 ?  1067 LYS R O   1 
ATOM 5298 C CB  . LYS B 1 441 ? 118.553 150.060 81.909  1.00 156.31 ?  1067 LYS R CB  1 
ATOM 5299 C CG  . LYS B 1 441 ? 118.228 150.085 80.425  1.00 156.31 ?  1067 LYS R CG  1 
ATOM 5300 C CD  . LYS B 1 441 ? 119.031 151.157 79.704  1.00 156.31 ?  1067 LYS R CD  1 
ATOM 5301 C CE  . LYS B 1 441 ? 118.839 151.078 78.198  1.00 156.31 ?  1067 LYS R CE  1 
ATOM 5302 N NZ  . LYS B 1 441 ? 119.715 152.041 77.475  1.00 156.31 1  1067 LYS R NZ  1 
ATOM 5303 N N   . LEU B 1 442 ? 119.553 147.112 82.083  1.00 156.78 ?  1068 LEU R N   1 
ATOM 5304 C CA  . LEU B 1 442 ? 119.951 145.855 81.458  1.00 156.78 ?  1068 LEU R CA  1 
ATOM 5305 C C   . LEU B 1 442 ? 119.168 144.684 82.037  1.00 156.78 ?  1068 LEU R C   1 
ATOM 5306 O O   . LEU B 1 442 ? 118.759 143.774 81.303  1.00 156.78 ?  1068 LEU R O   1 
ATOM 5307 C CB  . LEU B 1 442 ? 121.454 145.637 81.633  1.00 156.78 ?  1068 LEU R CB  1 
ATOM 5308 C CG  . LEU B 1 442 ? 122.027 144.318 81.110  1.00 156.78 ?  1068 LEU R CG  1 
ATOM 5309 C CD1 . LEU B 1 442 ? 121.899 144.224 79.596  1.00 156.78 ?  1068 LEU R CD1 1 
ATOM 5310 C CD2 . LEU B 1 442 ? 123.476 144.158 81.543  1.00 156.78 ?  1068 LEU R CD2 1 
ATOM 5311 N N   . GLY B 1 443 ? 118.957 144.687 83.354  1.00 154.58 ?  1069 GLY R N   1 
ATOM 5312 C CA  . GLY B 1 443 ? 118.207 143.607 83.971  1.00 154.58 ?  1069 GLY R CA  1 
ATOM 5313 C C   . GLY B 1 443 ? 116.785 143.521 83.455  1.00 154.58 ?  1069 GLY R C   1 
ATOM 5314 O O   . GLY B 1 443 ? 116.322 142.450 83.051  1.00 154.58 ?  1069 GLY R O   1 
ATOM 5315 N N   . ARG B 1 444 ? 116.077 144.656 83.437  1.00 152.41 ?  1070 ARG R N   1 
ATOM 5316 C CA  . ARG B 1 444 ? 114.705 144.632 82.942  1.00 152.41 ?  1070 ARG R CA  1 
ATOM 5317 C C   . ARG B 1 444 ? 114.671 144.269 81.466  1.00 152.41 ?  1070 ARG R C   1 
ATOM 5318 O O   . ARG B 1 444 ? 113.791 143.524 81.029  1.00 152.41 ?  1070 ARG R O   1 
ATOM 5319 C CB  . ARG B 1 444 ? 113.998 145.969 83.181  1.00 152.41 ?  1070 ARG R CB  1 
ATOM 5320 C CG  . ARG B 1 444 ? 114.769 147.202 82.776  1.00 152.41 ?  1070 ARG R CG  1 
ATOM 5321 C CD  . ARG B 1 444 ? 113.974 148.460 83.075  1.00 152.41 ?  1070 ARG R CD  1 
ATOM 5322 N NE  . ARG B 1 444 ? 113.864 148.716 84.505  1.00 152.41 ?  1070 ARG R NE  1 
ATOM 5323 C CZ  . ARG B 1 444 ? 114.679 149.505 85.191  1.00 152.41 ?  1070 ARG R CZ  1 
ATOM 5324 N NH1 . ARG B 1 444 ? 115.676 150.146 84.606  1.00 152.41 1  1070 ARG R NH1 1 
ATOM 5325 N NH2 . ARG B 1 444 ? 114.485 149.658 86.498  1.00 152.41 ?  1070 ARG R NH2 1 
ATOM 5326 N N   . GLU B 1 445 ? 115.632 144.772 80.687  1.00 151.68 ?  1071 GLU R N   1 
ATOM 5327 C CA  . GLU B 1 445 ? 115.729 144.429 79.272  1.00 151.68 ?  1071 GLU R CA  1 
ATOM 5328 C C   . GLU B 1 445 ? 115.811 142.918 79.068  1.00 151.68 ?  1071 GLU R C   1 
ATOM 5329 O O   . GLU B 1 445 ? 114.976 142.316 78.373  1.00 151.68 ?  1071 GLU R O   1 
ATOM 5330 C CB  . GLU B 1 445 ? 116.949 145.152 78.680  1.00 151.68 ?  1071 GLU R CB  1 
ATOM 5331 C CG  . GLU B 1 445 ? 117.809 144.375 77.680  1.00 151.68 ?  1071 GLU R CG  1 
ATOM 5332 C CD  . GLU B 1 445 ? 118.924 145.221 77.082  1.00 151.68 ?  1071 GLU R CD  1 
ATOM 5333 O OE1 . GLU B 1 445 ? 118.680 146.415 76.809  1.00 151.68 ?  1071 GLU R OE1 1 
ATOM 5334 O OE2 . GLU B 1 445 ? 120.039 144.695 76.880  1.00 151.68 -1 1071 GLU R OE2 1 
ATOM 5335 N N   . LEU B 1 446 ? 116.805 142.286 79.697  1.00 152.38 ?  1072 LEU R N   1 
ATOM 5336 C CA  . LEU B 1 446 ? 117.008 140.857 79.504  1.00 152.38 ?  1072 LEU R CA  1 
ATOM 5337 C C   . LEU B 1 446 ? 115.806 140.072 80.003  1.00 152.38 ?  1072 LEU R C   1 
ATOM 5338 O O   . LEU B 1 446 ? 115.328 139.149 79.328  1.00 152.38 ?  1072 LEU R O   1 
ATOM 5339 C CB  . LEU B 1 446 ? 118.289 140.413 80.212  1.00 152.38 ?  1072 LEU R CB  1 
ATOM 5340 C CG  . LEU B 1 446 ? 119.577 140.998 79.628  1.00 152.38 ?  1072 LEU R CG  1 
ATOM 5341 C CD1 . LEU B 1 446 ? 120.805 140.492 80.370  1.00 152.38 ?  1072 LEU R CD1 1 
ATOM 5342 C CD2 . LEU B 1 446 ? 119.672 140.681 78.146  1.00 152.38 ?  1072 LEU R CD2 1 
ATOM 5343 N N   . LEU B 1 447 ? 115.275 140.456 81.164  1.00 149.13 ?  1073 LEU R N   1 
ATOM 5344 C CA  . LEU B 1 447 ? 114.144 139.731 81.720  1.00 149.13 ?  1073 LEU R CA  1 
ATOM 5345 C C   . LEU B 1 447 ? 112.917 139.851 80.827  1.00 149.13 ?  1073 LEU R C   1 
ATOM 5346 O O   . LEU B 1 447 ? 112.151 138.892 80.697  1.00 149.13 ?  1073 LEU R O   1 
ATOM 5347 C CB  . LEU B 1 447 ? 113.852 140.228 83.135  1.00 149.13 ?  1073 LEU R CB  1 
ATOM 5348 C CG  . LEU B 1 447 ? 114.901 139.815 84.174  1.00 149.13 ?  1073 LEU R CG  1 
ATOM 5349 C CD1 . LEU B 1 447 ? 114.606 140.436 85.528  1.00 149.13 ?  1073 LEU R CD1 1 
ATOM 5350 C CD2 . LEU B 1 447 ? 114.984 138.295 84.287  1.00 149.13 ?  1073 LEU R CD2 1 
ATOM 5351 N N   . LEU B 1 448 ? 112.716 141.002 80.180  1.00 141.54 ?  1074 LEU R N   1 
ATOM 5352 C CA  . LEU B 1 448 ? 111.473 141.135 79.433  1.00 141.54 ?  1074 LEU R CA  1 
ATOM 5353 C C   . LEU B 1 448 ? 111.567 140.510 78.046  1.00 141.54 ?  1074 LEU R C   1 
ATOM 5354 O O   . LEU B 1 448 ? 110.566 139.964 77.573  1.00 141.54 ?  1074 LEU R O   1 
ATOM 5355 C CB  . LEU B 1 448 ? 111.006 142.597 79.373  1.00 141.54 ?  1074 LEU R CB  1 
ATOM 5356 C CG  . LEU B 1 448 ? 111.706 143.849 78.843  1.00 141.54 ?  1074 LEU R CG  1 
ATOM 5357 C CD1 . LEU B 1 448 ? 112.039 143.721 77.388  1.00 141.54 ?  1074 LEU R CD1 1 
ATOM 5358 C CD2 . LEU B 1 448 ? 110.836 145.075 79.084  1.00 141.54 ?  1074 LEU R CD2 1 
ATOM 5359 N N   . LYS B 1 449 ? 112.737 140.514 77.388  1.00 143.86 ?  1075 LYS R N   1 
ATOM 5360 C CA  . LYS B 1 449 ? 112.845 139.613 76.233  1.00 143.86 ?  1075 LYS R CA  1 
ATOM 5361 C C   . LYS B 1 449 ? 112.699 138.148 76.634  1.00 143.86 ?  1075 LYS R C   1 
ATOM 5362 O O   . LYS B 1 449 ? 112.085 137.368 75.897  1.00 143.86 ?  1075 LYS R O   1 
ATOM 5363 C CB  . LYS B 1 449 ? 114.113 139.794 75.380  1.00 143.86 ?  1075 LYS R CB  1 
ATOM 5364 C CG  . LYS B 1 449 ? 115.085 140.953 75.514  1.00 143.86 ?  1075 LYS R CG  1 
ATOM 5365 C CD  . LYS B 1 449 ? 114.370 142.290 75.378  1.00 143.86 ?  1075 LYS R CD  1 
ATOM 5366 C CE  . LYS B 1 449 ? 115.315 143.457 75.586  1.00 143.86 ?  1075 LYS R CE  1 
ATOM 5367 N NZ  . LYS B 1 449 ? 114.644 144.727 75.969  1.00 143.86 1  1075 LYS R NZ  1 
ATOM 5368 N N   . THR B 1 450 ? 113.245 137.743 77.785  1.00 144.51 ?  1076 THR R N   1 
ATOM 5369 C CA  . THR B 1 450 ? 113.064 136.356 78.208  1.00 144.51 ?  1076 THR R CA  1 
ATOM 5370 C C   . THR B 1 450 ? 111.587 136.031 78.392  1.00 144.51 ?  1076 THR R C   1 
ATOM 5371 O O   . THR B 1 450 ? 111.092 135.003 77.908  1.00 144.51 ?  1076 THR R O   1 
ATOM 5372 C CB  . THR B 1 450 ? 113.836 136.089 79.499  1.00 144.51 ?  1076 THR R CB  1 
ATOM 5373 O OG1 . THR B 1 450 ? 115.239 136.276 79.273  1.00 144.51 ?  1076 THR R OG1 1 
ATOM 5374 C CG2 . THR B 1 450 ? 113.581 134.663 79.981  1.00 144.51 ?  1076 THR R CG2 1 
ATOM 5375 N N   . ALA B 1 451 ? 110.864 136.912 79.082  1.00 147.36 ?  1077 ALA R N   1 
ATOM 5376 C CA  . ALA B 1 451 ? 109.442 136.697 79.299  1.00 147.36 ?  1077 ALA R CA  1 
ATOM 5377 C C   . ALA B 1 451 ? 108.687 136.685 77.979  1.00 147.36 ?  1077 ALA R C   1 
ATOM 5378 O O   . ALA B 1 451 ? 107.770 135.880 77.790  1.00 147.36 ?  1077 ALA R O   1 
ATOM 5379 C CB  . ALA B 1 451 ? 108.882 137.769 80.232  1.00 147.36 ?  1077 ALA R CB  1 
ATOM 5380 N N   . LYS B 1 452 ? 109.061 137.567 77.050  1.00 146.78 ?  1078 LYS R N   1 
ATOM 5381 C CA  . LYS B 1 452 ? 108.372 137.622 75.768  1.00 146.78 ?  1078 LYS R CA  1 
ATOM 5382 C C   . LYS B 1 452 ? 108.566 136.322 74.996  1.00 146.78 ?  1078 LYS R C   1 
ATOM 5383 O O   . LYS B 1 452 ? 107.596 135.758 74.476  1.00 146.78 ?  1078 LYS R O   1 
ATOM 5384 C CB  . LYS B 1 452 ? 108.870 138.842 74.977  1.00 146.78 ?  1078 LYS R CB  1 
ATOM 5385 C CG  . LYS B 1 452 ? 109.080 138.722 73.451  1.00 146.78 ?  1078 LYS R CG  1 
ATOM 5386 C CD  . LYS B 1 452 ? 107.848 138.242 72.670  1.00 146.78 ?  1078 LYS R CD  1 
ATOM 5387 C CE  . LYS B 1 452 ? 106.614 139.068 73.001  1.00 146.78 ?  1078 LYS R CE  1 
ATOM 5388 N NZ  . LYS B 1 452 ? 105.408 138.573 72.284  1.00 146.78 1  1078 LYS R NZ  1 
ATOM 5389 N N   . ILE B 1 453 ? 109.801 135.818 74.922  1.00 144.66 ?  1079 ILE R N   1 
ATOM 5390 C CA  . ILE B 1 453 ? 110.025 134.611 74.132  1.00 144.66 ?  1079 ILE R CA  1 
ATOM 5391 C C   . ILE B 1 453 ? 109.339 133.423 74.796  1.00 144.66 ?  1079 ILE R C   1 
ATOM 5392 O O   . ILE B 1 453 ? 108.763 132.564 74.116  1.00 144.66 ?  1079 ILE R O   1 
ATOM 5393 C CB  . ILE B 1 453 ? 111.530 134.353 73.909  1.00 144.66 ?  1079 ILE R CB  1 
ATOM 5394 C CG1 . ILE B 1 453 ? 111.776 132.940 73.379  1.00 144.66 ?  1079 ILE R CG1 1 
ATOM 5395 C CG2 . ILE B 1 453 ? 112.302 134.472 75.189  1.00 144.66 ?  1079 ILE R CG2 1 
ATOM 5396 C CD1 . ILE B 1 453 ? 111.104 132.654 72.046  1.00 144.66 ?  1079 ILE R CD1 1 
ATOM 5397 N N   . LEU B 1 454 ? 109.358 133.364 76.132  1.00 151.42 ?  1080 LEU R N   1 
ATOM 5398 C CA  . LEU B 1 454 ? 108.654 132.282 76.812  1.00 151.42 ?  1080 LEU R CA  1 
ATOM 5399 C C   . LEU B 1 454 ? 107.152 132.354 76.559  1.00 151.42 ?  1080 LEU R C   1 
ATOM 5400 O O   . LEU B 1 454 ? 106.509 131.330 76.299  1.00 151.42 ?  1080 LEU R O   1 
ATOM 5401 C CB  . LEU B 1 454 ? 108.948 132.316 78.312  1.00 151.42 ?  1080 LEU R CB  1 
ATOM 5402 C CG  . LEU B 1 454 ? 110.250 131.649 78.762  1.00 151.42 ?  1080 LEU R CG  1 
ATOM 5403 C CD1 . LEU B 1 454 ? 110.263 131.456 80.271  1.00 151.42 ?  1080 LEU R CD1 1 
ATOM 5404 C CD2 . LEU B 1 454 ? 110.450 130.321 78.048  1.00 151.42 ?  1080 LEU R CD2 1 
ATOM 5405 N N   . GLU B 1 455 ? 106.577 133.556 76.625  1.00 155.96 ?  1081 GLU R N   1 
ATOM 5406 C CA  . GLU B 1 455 ? 105.145 133.714 76.399  1.00 155.96 ?  1081 GLU R CA  1 
ATOM 5407 C C   . GLU B 1 455 ? 104.768 133.336 74.975  1.00 155.96 ?  1081 GLU R C   1 
ATOM 5408 O O   . GLU B 1 455 ? 103.732 132.701 74.746  1.00 155.96 ?  1081 GLU R O   1 
ATOM 5409 C CB  . GLU B 1 455 ? 104.728 135.154 76.701  1.00 155.96 ?  1081 GLU R CB  1 
ATOM 5410 C CG  . GLU B 1 455 ? 103.229 135.358 76.837  1.00 155.96 ?  1081 GLU R CG  1 
ATOM 5411 C CD  . GLU B 1 455 ? 102.864 136.804 77.116  1.00 155.96 ?  1081 GLU R CD  1 
ATOM 5412 O OE1 . GLU B 1 455 ? 103.476 137.701 76.499  1.00 155.96 ?  1081 GLU R OE1 1 
ATOM 5413 O OE2 . GLU B 1 455 ? 101.966 137.044 77.950  1.00 155.96 -1 1081 GLU R OE2 1 
ATOM 5414 N N   . GLU B 1 456 ? 105.596 133.723 74.003  1.00 157.97 ?  1082 GLU R N   1 
ATOM 5415 C CA  . GLU B 1 456 ? 105.309 133.392 72.612  1.00 157.97 ?  1082 GLU R CA  1 
ATOM 5416 C C   . GLU B 1 456 ? 105.340 131.888 72.379  1.00 157.97 ?  1082 GLU R C   1 
ATOM 5417 O O   . GLU B 1 456 ? 104.648 131.386 71.485  1.00 157.97 ?  1082 GLU R O   1 
ATOM 5418 C CB  . GLU B 1 456 ? 106.303 134.100 71.692  1.00 157.97 ?  1082 GLU R CB  1 
ATOM 5419 C CG  . GLU B 1 456 ? 105.999 133.948 70.209  1.00 157.97 ?  1082 GLU R CG  1 
ATOM 5420 C CD  . GLU B 1 456 ? 106.873 134.830 69.341  1.00 157.97 ?  1082 GLU R CD  1 
ATOM 5421 O OE1 . GLU B 1 456 ? 106.602 136.047 69.265  1.00 157.97 ?  1082 GLU R OE1 1 
ATOM 5422 O OE2 . GLU B 1 456 ? 107.832 134.307 68.735  1.00 157.97 -1 1082 GLU R OE2 1 
ATOM 5423 N N   . ARG B 1 457 ? 106.118 131.155 73.173  1.00 153.79 ?  1083 ARG R N   1 
ATOM 5424 C CA  . ARG B 1 457 ? 106.201 129.709 73.025  1.00 153.79 ?  1083 ARG R CA  1 
ATOM 5425 C C   . ARG B 1 457 ? 104.998 128.977 73.608  1.00 153.79 ?  1083 ARG R C   1 
ATOM 5426 O O   . ARG B 1 457 ? 104.881 127.763 73.410  1.00 153.79 ?  1083 ARG R O   1 
ATOM 5427 C CB  . ARG B 1 457 ? 107.488 129.191 73.670  1.00 153.79 ?  1083 ARG R CB  1 
ATOM 5428 C CG  . ARG B 1 457 ? 108.738 129.486 72.855  1.00 153.79 ?  1083 ARG R CG  1 
ATOM 5429 C CD  . ARG B 1 457 ? 109.994 129.053 73.589  1.00 153.79 ?  1083 ARG R CD  1 
ATOM 5430 N NE  . ARG B 1 457 ? 111.201 129.518 72.918  1.00 153.79 ?  1083 ARG R NE  1 
ATOM 5431 C CZ  . ARG B 1 457 ? 112.409 129.522 73.466  1.00 153.79 ?  1083 ARG R CZ  1 
ATOM 5432 N NH1 . ARG B 1 457 ? 112.610 129.089 74.699  1.00 153.79 1  1083 ARG R NH1 1 
ATOM 5433 N NH2 . ARG B 1 457 ? 113.440 129.974 72.759  1.00 153.79 ?  1083 ARG R NH2 1 
ATOM 5434 N N   . GLY B 1 458 ? 104.109 129.672 74.315  1.00 155.26 ?  1084 GLY R N   1 
ATOM 5435 C CA  . GLY B 1 458 ? 102.886 129.052 74.789  1.00 155.26 ?  1084 GLY R CA  1 
ATOM 5436 C C   . GLY B 1 458 ? 102.698 129.065 76.292  1.00 155.26 ?  1084 GLY R C   1 
ATOM 5437 O O   . GLY B 1 458 ? 101.850 128.339 76.819  1.00 155.26 ?  1084 GLY R O   1 
ATOM 5438 N N   . ALA B 1 459 ? 103.476 129.883 76.995  1.00 152.48 ?  1085 ALA R N   1 
ATOM 5439 C CA  . ALA B 1 459 ? 103.372 129.942 78.447  1.00 152.48 ?  1085 ALA R CA  1 
ATOM 5440 C C   . ALA B 1 459 ? 102.103 130.677 78.859  1.00 152.48 ?  1085 ALA R C   1 
ATOM 5441 O O   . ALA B 1 459 ? 101.889 131.832 78.478  1.00 152.48 ?  1085 ALA R O   1 
ATOM 5442 C CB  . ALA B 1 459 ? 104.600 130.630 79.039  1.00 152.48 ?  1085 ALA R CB  1 
ATOM 5443 N N   . GLU B 1 460 ? 101.260 130.004 79.639  1.00 142.46 ?  1086 GLU R N   1 
ATOM 5444 C CA  . GLU B 1 460 ? 100.035 130.601 80.152  1.00 142.46 ?  1086 GLU R CA  1 
ATOM 5445 C C   . GLU B 1 460 ? 100.260 131.466 81.385  1.00 142.46 ?  1086 GLU R C   1 
ATOM 5446 O O   . GLU B 1 460 ? 99.388  132.273 81.723  1.00 142.46 ?  1086 GLU R O   1 
ATOM 5447 C CB  . GLU B 1 460 ? 99.016  129.504 80.472  1.00 142.46 ?  1086 GLU R CB  1 
ATOM 5448 C CG  . GLU B 1 460 ? 98.908  128.442 79.392  1.00 142.46 ?  1086 GLU R CG  1 
ATOM 5449 C CD  . GLU B 1 460 ? 98.731  127.048 79.953  1.00 142.46 ?  1086 GLU R CD  1 
ATOM 5450 O OE1 . GLU B 1 460 ? 98.405  126.924 81.150  1.00 142.46 ?  1086 GLU R OE1 1 
ATOM 5451 O OE2 . GLU B 1 460 ? 98.896  126.075 79.190  1.00 142.46 -1 1086 GLU R OE2 1 
ATOM 5452 N N   . CYS B 1 461 ? 101.399 131.317 82.058  1.00 149.35 ?  1087 CYS R N   1 
ATOM 5453 C CA  . CYS B 1 461 ? 101.746 132.160 83.193  1.00 149.35 ?  1087 CYS R CA  1 
ATOM 5454 C C   . CYS B 1 461 ? 103.250 132.082 83.408  1.00 149.35 ?  1087 CYS R C   1 
ATOM 5455 O O   . CYS B 1 461 ? 103.910 131.138 82.967  1.00 149.35 ?  1087 CYS R O   1 
ATOM 5456 C CB  . CYS B 1 461 ? 100.988 131.749 84.461  1.00 149.35 ?  1087 CYS R CB  1 
ATOM 5457 S SG  . CYS B 1 461 ? 101.571 130.224 85.229  1.00 149.35 ?  1087 CYS R SG  1 
ATOM 5458 N N   . ILE B 1 462 ? 103.779 133.093 84.093  1.00 148.53 ?  1088 ILE R N   1 
ATOM 5459 C CA  . ILE B 1 462 ? 105.212 133.254 84.308  1.00 148.53 ?  1088 ILE R CA  1 
ATOM 5460 C C   . ILE B 1 462 ? 105.466 133.339 85.806  1.00 148.53 ?  1088 ILE R C   1 
ATOM 5461 O O   . ILE B 1 462 ? 104.744 134.042 86.523  1.00 148.53 ?  1088 ILE R O   1 
ATOM 5462 C CB  . ILE B 1 462 ? 105.753 134.505 83.591  1.00 148.53 ?  1088 ILE R CB  1 
ATOM 5463 C CG1 . ILE B 1 462 ? 105.455 134.436 82.091  1.00 148.53 ?  1088 ILE R CG1 1 
ATOM 5464 C CG2 . ILE B 1 462 ? 107.246 134.659 83.832  1.00 148.53 ?  1088 ILE R CG2 1 
ATOM 5465 C CD1 . ILE B 1 462 ? 106.096 133.257 81.393  1.00 148.53 ?  1088 ILE R CD1 1 
ATOM 5466 N N   . ILE B 1 463 ? 106.488 132.627 86.275  1.00 137.13 ?  1089 ILE R N   1 
ATOM 5467 C CA  . ILE B 1 463 ? 106.872 132.615 87.681  1.00 137.13 ?  1089 ILE R CA  1 
ATOM 5468 C C   . ILE B 1 463 ? 108.233 133.280 87.813  1.00 137.13 ?  1089 ILE R C   1 
ATOM 5469 O O   . ILE B 1 463 ? 109.144 133.011 87.018  1.00 137.13 ?  1089 ILE R O   1 
ATOM 5470 C CB  . ILE B 1 463 ? 106.899 131.186 88.247  1.00 137.13 ?  1089 ILE R CB  1 
ATOM 5471 C CG1 . ILE B 1 463 ? 105.555 130.496 88.008  1.00 137.13 ?  1089 ILE R CG1 1 
ATOM 5472 C CG2 . ILE B 1 463 ? 107.227 131.207 89.729  1.00 137.13 ?  1089 ILE R CG2 1 
ATOM 5473 C CD1 . ILE B 1 463 ? 105.606 128.992 88.151  1.00 137.13 ?  1089 ILE R CD1 1 
ATOM 5474 N N   . ALA B 1 464 ? 108.360 134.166 88.798  1.00 129.95 ?  1090 ALA R N   1 
ATOM 5475 C CA  . ALA B 1 464 ? 109.598 134.893 89.070  1.00 129.95 ?  1090 ALA R CA  1 
ATOM 5476 C C   . ALA B 1 464 ? 110.205 134.323 90.347  1.00 129.95 ?  1090 ALA R C   1 
ATOM 5477 O O   . ALA B 1 464 ? 109.846 134.713 91.458  1.00 129.95 ?  1090 ALA R O   1 
ATOM 5478 C CB  . ALA B 1 464 ? 109.332 136.388 89.190  1.00 129.95 ?  1090 ALA R CB  1 
ATOM 5479 N N   . GLY B 1 465 ? 111.151 133.400 90.182  1.00 125.95 ?  1091 GLY R N   1 
ATOM 5480 C CA  . GLY B 1 465 ? 111.741 132.706 91.312  1.00 125.95 ?  1091 GLY R CA  1 
ATOM 5481 C C   . GLY B 1 465 ? 112.580 133.575 92.222  1.00 125.95 ?  1091 GLY R C   1 
ATOM 5482 O O   . GLY B 1 465 ? 112.995 133.105 93.286  1.00 125.95 ?  1091 GLY R O   1 
ATOM 5483 N N   . CYS B 1 466 ? 112.847 134.816 91.832  1.00 135.49 ?  1092 CYS R N   1 
ATOM 5484 C CA  . CYS B 1 466 ? 113.626 135.734 92.643  1.00 135.49 ?  1092 CYS R CA  1 
ATOM 5485 C C   . CYS B 1 466 ? 112.926 137.082 92.697  1.00 135.49 ?  1092 CYS R C   1 
ATOM 5486 O O   . CYS B 1 466 ? 112.176 137.450 91.788  1.00 135.49 ?  1092 CYS R O   1 
ATOM 5487 C CB  . CYS B 1 466 ? 115.048 135.906 92.093  1.00 135.49 ?  1092 CYS R CB  1 
ATOM 5488 S SG  . CYS B 1 466 ? 115.998 134.372 91.987  1.00 135.49 ?  1092 CYS R SG  1 
ATOM 5489 N N   . THR B 1 467 ? 113.177 137.815 93.782  1.00 148.58 ?  1093 THR R N   1 
ATOM 5490 C CA  . THR B 1 467 ? 112.588 139.140 93.929  1.00 148.58 ?  1093 THR R CA  1 
ATOM 5491 C C   . THR B 1 467 ? 113.122 140.114 92.887  1.00 148.58 ?  1093 THR R C   1 
ATOM 5492 O O   . THR B 1 467 ? 112.446 141.094 92.556  1.00 148.58 ?  1093 THR R O   1 
ATOM 5493 C CB  . THR B 1 467 ? 112.849 139.677 95.335  1.00 148.58 ?  1093 THR R CB  1 
ATOM 5494 O OG1 . THR B 1 467 ? 114.260 139.718 95.578  1.00 148.58 ?  1093 THR R OG1 1 
ATOM 5495 C CG2 . THR B 1 467 ? 112.188 138.784 96.374  1.00 148.58 ?  1093 THR R CG2 1 
ATOM 5496 N N   . GLU B 1 468 ? 114.324 139.861 92.361  1.00 157.67 ?  1094 GLU R N   1 
ATOM 5497 C CA  . GLU B 1 468 ? 114.914 140.770 91.383  1.00 157.67 ?  1094 GLU R CA  1 
ATOM 5498 C C   . GLU B 1 468 ? 114.066 140.851 90.121  1.00 157.67 ?  1094 GLU R C   1 
ATOM 5499 O O   . GLU B 1 468 ? 113.913 141.930 89.535  1.00 157.67 ?  1094 GLU R O   1 
ATOM 5500 C CB  . GLU B 1 468 ? 116.338 140.328 91.040  1.00 157.67 ?  1094 GLU R CB  1 
ATOM 5501 C CG  . GLU B 1 468 ? 117.373 140.653 92.106  1.00 157.67 ?  1094 GLU R CG  1 
ATOM 5502 C CD  . GLU B 1 468 ? 117.300 139.719 93.297  1.00 157.67 ?  1094 GLU R CD  1 
ATOM 5503 O OE1 . GLU B 1 468 ? 116.991 138.525 93.100  1.00 157.67 ?  1094 GLU R OE1 1 
ATOM 5504 O OE2 . GLU B 1 468 ? 117.553 140.178 94.431  1.00 157.67 -1 1094 GLU R OE2 1 
ATOM 5505 N N   . VAL B 1 469 ? 113.516 139.719 89.679  1.00 156.07 ?  1095 VAL R N   1 
ATOM 5506 C CA  . VAL B 1 469 ? 112.662 139.722 88.495  1.00 156.07 ?  1095 VAL R CA  1 
ATOM 5507 C C   . VAL B 1 469 ? 111.405 140.543 88.751  1.00 156.07 ?  1095 VAL R C   1 
ATOM 5508 O O   . VAL B 1 469 ? 110.994 141.361 87.920  1.00 156.07 ?  1095 VAL R O   1 
ATOM 5509 C CB  . VAL B 1 469 ? 112.321 138.282 88.073  1.00 156.07 ?  1095 VAL R CB  1 
ATOM 5510 C CG1 . VAL B 1 469 ? 111.417 138.289 86.849  1.00 156.07 ?  1095 VAL R CG1 1 
ATOM 5511 C CG2 . VAL B 1 469 ? 113.592 137.493 87.799  1.00 156.07 ?  1095 VAL R CG2 1 
ATOM 5512 N N   . SER B 1 470 ? 110.781 140.345 89.914  1.00 154.54 ?  1096 SER R N   1 
ATOM 5513 C CA  . SER B 1 470 ? 109.571 141.088 90.244  1.00 154.54 ?  1096 SER R CA  1 
ATOM 5514 C C   . SER B 1 470 ? 109.835 142.575 90.438  1.00 154.54 ?  1096 SER R C   1 
ATOM 5515 O O   . SER B 1 470 ? 108.915 143.381 90.262  1.00 154.54 ?  1096 SER R O   1 
ATOM 5516 C CB  . SER B 1 470 ? 108.926 140.504 91.500  1.00 154.54 ?  1096 SER R CB  1 
ATOM 5517 O OG  . SER B 1 470 ? 109.900 140.240 92.493  1.00 154.54 ?  1096 SER R OG  1 
ATOM 5518 N N   . VAL B 1 471 ? 111.064 142.953 90.797  1.00 158.56 ?  1097 VAL R N   1 
ATOM 5519 C CA  . VAL B 1 471 ? 111.381 144.364 91.001  1.00 158.56 ?  1097 VAL R CA  1 
ATOM 5520 C C   . VAL B 1 471 ? 111.206 145.148 89.706  1.00 158.56 ?  1097 VAL R C   1 
ATOM 5521 O O   . VAL B 1 471 ? 110.612 146.233 89.694  1.00 158.56 ?  1097 VAL R O   1 
ATOM 5522 C CB  . VAL B 1 471 ? 112.805 144.516 91.567  1.00 158.56 ?  1097 VAL R CB  1 
ATOM 5523 C CG1 . VAL B 1 471 ? 113.342 145.916 91.304  1.00 158.56 ?  1097 VAL R CG1 1 
ATOM 5524 C CG2 . VAL B 1 471 ? 112.817 144.219 93.058  1.00 158.56 ?  1097 VAL R CG2 1 
ATOM 5525 N N   . VAL B 1 472 ? 111.702 144.605 88.592  1.00 163.31 ?  1098 VAL R N   1 
ATOM 5526 C CA  . VAL B 1 472 ? 111.689 145.325 87.321  1.00 163.31 ?  1098 VAL R CA  1 
ATOM 5527 C C   . VAL B 1 472 ? 110.588 144.858 86.378  1.00 163.31 ?  1098 VAL R C   1 
ATOM 5528 O O   . VAL B 1 472 ? 110.407 145.468 85.311  1.00 163.31 ?  1098 VAL R O   1 
ATOM 5529 C CB  . VAL B 1 472 ? 113.055 145.220 86.610  1.00 163.31 ?  1098 VAL R CB  1 
ATOM 5530 C CG1 . VAL B 1 472 ? 114.137 145.895 87.437  1.00 163.31 ?  1098 VAL R CG1 1 
ATOM 5531 C CG2 . VAL B 1 472 ? 113.404 143.766 86.348  1.00 163.31 ?  1098 VAL R CG2 1 
ATOM 5532 N N   . LEU B 1 473 ? 109.851 143.806 86.725  1.00 158.25 ?  1099 LEU R N   1 
ATOM 5533 C CA  . LEU B 1 473 ? 108.783 143.285 85.882  1.00 158.25 ?  1099 LEU R CA  1 
ATOM 5534 C C   . LEU B 1 473 ? 107.457 143.415 86.615  1.00 158.25 ?  1099 LEU R C   1 
ATOM 5535 O O   . LEU B 1 473 ? 107.358 143.061 87.794  1.00 158.25 ?  1099 LEU R O   1 
ATOM 5536 C CB  . LEU B 1 473 ? 109.042 141.825 85.496  1.00 158.25 ?  1099 LEU R CB  1 
ATOM 5537 C CG  . LEU B 1 473 ? 108.192 141.250 84.362  1.00 158.25 ?  1099 LEU R CG  1 
ATOM 5538 C CD1 . LEU B 1 473 ? 108.471 141.979 83.057  1.00 158.25 ?  1099 LEU R CD1 1 
ATOM 5539 C CD2 . LEU B 1 473 ? 108.444 139.757 84.208  1.00 158.25 ?  1099 LEU R CD2 1 
ATOM 5540 N N   . LYS B 1 474 ? 106.447 143.929 85.918  1.00 154.98 ?  1100 LYS R N   1 
ATOM 5541 C CA  . LYS B 1 474 ? 105.118 144.137 86.471  1.00 154.98 ?  1100 LYS R CA  1 
ATOM 5542 C C   . LYS B 1 474 ? 104.086 143.400 85.627  1.00 154.98 ?  1100 LYS R C   1 
ATOM 5543 O O   . LYS B 1 474 ? 104.379 142.896 84.540  1.00 154.98 ?  1100 LYS R O   1 
ATOM 5544 C CB  . LYS B 1 474 ? 104.779 145.631 86.546  1.00 154.98 ?  1100 LYS R CB  1 
ATOM 5545 C CG  . LYS B 1 474 ? 105.702 146.429 87.449  1.00 154.98 ?  1100 LYS R CG  1 
ATOM 5546 C CD  . LYS B 1 474 ? 105.805 145.794 88.825  1.00 154.98 ?  1100 LYS R CD  1 
ATOM 5547 C CE  . LYS B 1 474 ? 107.138 146.105 89.481  1.00 154.98 ?  1100 LYS R CE  1 
ATOM 5548 N NZ  . LYS B 1 474 ? 108.230 145.253 88.943  1.00 154.98 1  1100 LYS R NZ  1 
ATOM 5549 N N   . GLN B 1 475 ? 102.858 143.345 86.150  1.00 155.14 ?  1101 GLN R N   1 
ATOM 5550 C CA  . GLN B 1 475 ? 101.796 142.602 85.479  1.00 155.14 ?  1101 GLN R CA  1 
ATOM 5551 C C   . GLN B 1 475 ? 101.443 143.207 84.127  1.00 155.14 ?  1101 GLN R C   1 
ATOM 5552 O O   . GLN B 1 475 ? 101.173 142.472 83.170  1.00 155.14 ?  1101 GLN R O   1 
ATOM 5553 C CB  . GLN B 1 475 ? 100.558 142.540 86.371  1.00 155.14 ?  1101 GLN R CB  1 
ATOM 5554 C CG  . GLN B 1 475 ? 99.379  141.810 85.750  1.00 155.14 ?  1101 GLN R CG  1 
ATOM 5555 C CD  . GLN B 1 475 ? 99.783  140.501 85.104  1.00 155.14 ?  1101 GLN R CD  1 
ATOM 5556 O OE1 . GLN B 1 475 ? 100.031 139.512 85.791  1.00 155.14 ?  1101 GLN R OE1 1 
ATOM 5557 N NE2 . GLN B 1 475 ? 99.840  140.485 83.778  1.00 155.14 ?  1101 GLN R NE2 1 
ATOM 5558 N N   . ASP B 1 476 ? 101.440 144.537 84.025  1.00 159.26 ?  1102 ASP R N   1 
ATOM 5559 C CA  . ASP B 1 476 ? 101.066 145.200 82.781  1.00 159.26 ?  1102 ASP R CA  1 
ATOM 5560 C C   . ASP B 1 476 ? 102.035 144.918 81.641  1.00 159.26 ?  1102 ASP R C   1 
ATOM 5561 O O   . ASP B 1 476 ? 101.687 145.169 80.482  1.00 159.26 ?  1102 ASP R O   1 
ATOM 5562 C CB  . ASP B 1 476 ? 100.963 146.711 83.004  1.00 159.26 ?  1102 ASP R CB  1 
ATOM 5563 C CG  . ASP B 1 476 ? 102.266 147.321 83.491  1.00 159.26 ?  1102 ASP R CG  1 
ATOM 5564 O OD1 . ASP B 1 476 ? 103.175 146.559 83.883  1.00 159.26 ?  1102 ASP R OD1 1 
ATOM 5565 O OD2 . ASP B 1 476 ? 102.381 148.564 83.480  1.00 159.26 -1 1102 ASP R OD2 1 
ATOM 5566 N N   . ASP B 1 477 ? 103.229 144.407 81.934  1.00 162.70 ?  1103 ASP R N   1 
ATOM 5567 C CA  . ASP B 1 477 ? 104.230 144.157 80.909  1.00 162.70 ?  1103 ASP R CA  1 
ATOM 5568 C C   . ASP B 1 477 ? 103.983 142.873 80.129  1.00 162.70 ?  1103 ASP R C   1 
ATOM 5569 O O   . ASP B 1 477 ? 104.603 142.679 79.078  1.00 162.70 ?  1103 ASP R O   1 
ATOM 5570 C CB  . ASP B 1 477 ? 105.626 144.110 81.540  1.00 162.70 ?  1103 ASP R CB  1 
ATOM 5571 C CG  . ASP B 1 477 ? 106.072 145.460 82.067  1.00 162.70 ?  1103 ASP R CG  1 
ATOM 5572 O OD1 . ASP B 1 477 ? 106.039 146.441 81.294  1.00 162.70 ?  1103 ASP R OD1 1 
ATOM 5573 O OD2 . ASP B 1 477 ? 106.452 145.542 83.254  1.00 162.70 -1 1103 ASP R OD2 1 
ATOM 5574 N N   . LEU B 1 478 ? 103.101 141.999 80.608  1.00 158.53 ?  1104 LEU R N   1 
ATOM 5575 C CA  . LEU B 1 478 ? 102.812 140.743 79.936  1.00 158.53 ?  1104 LEU R CA  1 
ATOM 5576 C C   . LEU B 1 478 ? 101.309 140.511 79.892  1.00 158.53 ?  1104 LEU R C   1 
ATOM 5577 O O   . LEU B 1 478 ? 100.565 140.977 80.759  1.00 158.53 ?  1104 LEU R O   1 
ATOM 5578 C CB  . LEU B 1 478 ? 103.496 139.557 80.634  1.00 158.53 ?  1104 LEU R CB  1 
ATOM 5579 C CG  . LEU B 1 478 ? 105.022 139.593 80.722  1.00 158.53 ?  1104 LEU R CG  1 
ATOM 5580 C CD1 . LEU B 1 478 ? 105.529 138.525 81.679  1.00 158.53 ?  1104 LEU R CD1 1 
ATOM 5581 C CD2 . LEU B 1 478 ? 105.642 139.421 79.344  1.00 158.53 ?  1104 LEU R CD2 1 
ATOM 5582 N N   . LYS B 1 479 ? 100.872 139.780 78.865  1.00 154.84 ?  1105 LYS R N   1 
ATOM 5583 C CA  . LYS B 1 479 ? 99.461  139.430 78.755  1.00 154.84 ?  1105 LYS R CA  1 
ATOM 5584 C C   . LYS B 1 479 ? 99.063  138.379 79.783  1.00 154.84 ?  1105 LYS R C   1 
ATOM 5585 O O   . LYS B 1 479 ? 97.965  138.449 80.347  1.00 154.84 ?  1105 LYS R O   1 
ATOM 5586 C CB  . LYS B 1 479 ? 99.154  138.928 77.344  1.00 154.84 ?  1105 LYS R CB  1 
ATOM 5587 C CG  . LYS B 1 479 ? 99.881  139.682 76.244  1.00 154.84 ?  1105 LYS R CG  1 
ATOM 5588 C CD  . LYS B 1 479 ? 99.818  138.924 74.927  1.00 154.84 ?  1105 LYS R CD  1 
ATOM 5589 C CE  . LYS B 1 479 ? 100.768 139.518 73.900  1.00 154.84 ?  1105 LYS R CE  1 
ATOM 5590 N NZ  . LYS B 1 479 ? 100.327 140.866 73.449  1.00 154.84 1  1105 LYS R NZ  1 
ATOM 5591 N N   . VAL B 1 480 ? 99.934  137.408 80.039  1.00 153.95 ?  1106 VAL R N   1 
ATOM 5592 C CA  . VAL B 1 480 ? 99.645  136.319 80.968  1.00 153.95 ?  1106 VAL R CA  1 
ATOM 5593 C C   . VAL B 1 480 ? 99.801  136.824 82.398  1.00 153.95 ?  1106 VAL R C   1 
ATOM 5594 O O   . VAL B 1 480 ? 100.506 137.818 82.629  1.00 153.95 ?  1106 VAL R O   1 
ATOM 5595 C CB  . VAL B 1 480 ? 100.554 135.109 80.702  1.00 153.95 ?  1106 VAL R CB  1 
ATOM 5596 C CG1 . VAL B 1 480 ? 100.271 134.530 79.325  1.00 153.95 ?  1106 VAL R CG1 1 
ATOM 5597 C CG2 . VAL B 1 480 ? 102.017 135.501 80.837  1.00 153.95 ?  1106 VAL R CG2 1 
ATOM 5598 N N   . PRO B 1 481 ? 99.155  136.194 83.378  1.00 151.64 ?  1107 PRO R N   1 
ATOM 5599 C CA  . PRO B 1 481 ? 99.335  136.622 84.769  1.00 151.64 ?  1107 PRO R CA  1 
ATOM 5600 C C   . PRO B 1 481 ? 100.761 136.391 85.247  1.00 151.64 ?  1107 PRO R C   1 
ATOM 5601 O O   . PRO B 1 481 ? 101.447 135.466 84.807  1.00 151.64 ?  1107 PRO R O   1 
ATOM 5602 C CB  . PRO B 1 481 ? 98.339  135.748 85.542  1.00 151.64 ?  1107 PRO R CB  1 
ATOM 5603 C CG  . PRO B 1 481 ? 97.337  135.318 84.517  1.00 151.64 ?  1107 PRO R CG  1 
ATOM 5604 C CD  . PRO B 1 481 ? 98.127  135.146 83.258  1.00 151.64 ?  1107 PRO R CD  1 
ATOM 5605 N N   . LEU B 1 482 ? 101.203 137.251 86.161  1.00 153.05 ?  1108 LEU R N   1 
ATOM 5606 C CA  . LEU B 1 482 ? 102.507 137.129 86.802  1.00 153.05 ?  1108 LEU R CA  1 
ATOM 5607 C C   . LEU B 1 482 ? 102.298 136.735 88.257  1.00 153.05 ?  1108 LEU R C   1 
ATOM 5608 O O   . LEU B 1 482 ? 101.624 137.450 89.007  1.00 153.05 ?  1108 LEU R O   1 
ATOM 5609 C CB  . LEU B 1 482 ? 103.299 138.432 86.708  1.00 153.05 ?  1108 LEU R CB  1 
ATOM 5610 C CG  . LEU B 1 482 ? 103.970 138.783 85.378  1.00 153.05 ?  1108 LEU R CG  1 
ATOM 5611 C CD1 . LEU B 1 482 ? 102.957 139.198 84.321  1.00 153.05 ?  1108 LEU R CD1 1 
ATOM 5612 C CD2 . LEU B 1 482 ? 105.003 139.876 85.589  1.00 153.05 ?  1108 LEU R CD2 1 
ATOM 5613 N N   . ILE B 1 483 ? 102.877 135.605 88.653  1.00 151.86 ?  1109 ILE R N   1 
ATOM 5614 C CA  . ILE B 1 483 ? 102.745 135.073 90.003  1.00 151.86 ?  1109 ILE R CA  1 
ATOM 5615 C C   . ILE B 1 483 ? 104.127 135.004 90.631  1.00 151.86 ?  1109 ILE R C   1 
ATOM 5616 O O   . ILE B 1 483 ? 105.092 134.581 89.984  1.00 151.86 ?  1109 ILE R O   1 
ATOM 5617 C CB  . ILE B 1 483 ? 102.077 133.683 90.010  1.00 151.86 ?  1109 ILE R CB  1 
ATOM 5618 C CG1 . ILE B 1 483 ? 100.919 133.637 89.012  1.00 151.86 ?  1109 ILE R CG1 1 
ATOM 5619 C CG2 . ILE B 1 483 ? 101.592 133.331 91.407  1.00 151.86 ?  1109 ILE R CG2 1 
ATOM 5620 C CD1 . ILE B 1 483 ? 100.457 132.236 88.682  1.00 151.86 ?  1109 ILE R CD1 1 
ATOM 5621 N N   . ASP B 1 484 ? 104.222 135.418 91.889  1.00 151.86 ?  1110 ASP R N   1 
ATOM 5622 C CA  . ASP B 1 484 ? 105.486 135.404 92.604  1.00 151.86 ?  1110 ASP R CA  1 
ATOM 5623 C C   . ASP B 1 484 ? 105.320 134.722 93.953  1.00 151.86 ?  1110 ASP R C   1 
ATOM 5624 O O   . ASP B 1 484 ? 104.231 134.739 94.534  1.00 151.86 ?  1110 ASP R O   1 
ATOM 5625 C CB  . ASP B 1 484 ? 106.020 136.830 92.813  1.00 151.86 ?  1110 ASP R CB  1 
ATOM 5626 C CG  . ASP B 1 484 ? 104.947 137.791 93.285  1.00 151.86 ?  1110 ASP R CG  1 
ATOM 5627 O OD1 . ASP B 1 484 ? 103.784 137.362 93.436  1.00 151.86 ?  1110 ASP R OD1 1 
ATOM 5628 O OD2 . ASP B 1 484 ? 105.268 138.978 93.506  1.00 151.86 -1 1110 ASP R OD2 1 
ATOM 5629 N N   . PRO B 1 485 ? 106.388 134.099 94.472  1.00 138.92 ?  1111 PRO R N   1 
ATOM 5630 C CA  . PRO B 1 485 ? 106.369 133.509 95.812  1.00 138.92 ?  1111 PRO R CA  1 
ATOM 5631 C C   . PRO B 1 485 ? 106.179 134.561 96.899  1.00 138.92 ?  1111 PRO R C   1 
ATOM 5632 O O   . PRO B 1 485 ? 105.638 134.280 97.968  1.00 138.92 ?  1111 PRO R O   1 
ATOM 5633 C CB  . PRO B 1 485 ? 107.749 132.854 95.925  1.00 138.92 ?  1111 PRO R CB  1 
ATOM 5634 C CG  . PRO B 1 485 ? 108.160 132.603 94.515  1.00 138.92 ?  1111 PRO R CG  1 
ATOM 5635 C CD  . PRO B 1 485 ? 107.633 133.779 93.753  1.00 138.92 ?  1111 PRO R CD  1 
ATOM 5636 O OXT . PRO B 1 485 ? 106.560 135.719 96.732  1.00 138.92 -1 1111 PRO R OXT 1 
# 
