data_9LF7
# 
_entry.id   9LF7 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9LF7         pdb_00009lf7 10.2210/pdb9lf7/pdb 
WWPDB D_1300055445 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-02-19 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9LF7 
_pdbx_database_status.recvd_initial_deposition_date   2025-01-08 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              yuehongwu@sio.org.cn 
_pdbx_contact_author.name_first         Wu 
_pdbx_contact_author.name_last          Yuehong 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-1593-8662 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Rong, Z.' 1 0000-0002-6592-2554 
'Wu, Y.H.' 2 0000-0002-1593-8662 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Structure of a PAE-hydrolyzing eaterse' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Rong, Z.'    1 0000-0002-6592-2554 
primary 'Hong, L.G.'  2 ?                   
primary 'Huo, Y.Y.'   3 ?                   
primary 'Zheng, D.Q.' 4 ?                   
primary 'Xu, X.W.'    5 ?                   
primary 'Li, J.X.'    6 ?                   
primary 'Wu, Y.H.'    7 ?                   
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man Poc14_A                                35741.000 2   3.1.1.1 ? ? ? 
2 non-polymer syn '2-(N-MORPHOLINO)-ETHANESULFONIC ACID' 195.237   2   ?       ? ? ? 
3 water       nat water                                  18.015    879 ?       ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MRLAKLPALAYRSAKDTGESMTDTPYIRPDMKAFLEMMAQVNGPKLSEMSLDEARASYLAMHNLADRPARALPVIRDLSC
PGPKGEIALRLYDPRESRAGPTPVITFFHGGGFVIGDLDTHHALCTEIAALMDLPLVAVHYARAPEAPFPAAILDCEAAT
RWIASSPAELGLTASGIITIGDSAGGNATVVVGQLLAASPAAVPVVLQVPIFPLVADAVSSESMAAFSEGYLLTAETMAF
FDAAYGADRSDPRGFPILGRHDNAPPTIVVTASLDPIRDSGRAYAKALIDAGRDCVFLEMRGVTHSFTNLRQMVPSTQAD
LERVIAAMQFMLANPA
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MRLAKLPALAYRSAKDTGESMTDTPYIRPDMKAFLEMMAQVNGPKLSEMSLDEARASYLAMHNLADRPARALPVIRDLSC
PGPKGEIALRLYDPRESRAGPTPVITFFHGGGFVIGDLDTHHALCTEIAALMDLPLVAVHYARAPEAPFPAAILDCEAAT
RWIASSPAELGLTASGIITIGDSAGGNATVVVGQLLAASPAAVPVVLQVPIFPLVADAVSSESMAAFSEGYLLTAETMAF
FDAAYGADRSDPRGFPILGRHDNAPPTIVVTASLDPIRDSGRAYAKALIDAGRDCVFLEMRGVTHSFTNLRQMVPSTQAD
LERVIAAMQFMLANPA
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 '2-(N-MORPHOLINO)-ETHANESULFONIC ACID' MES 
3 water                                  HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ARG n 
1 3   LEU n 
1 4   ALA n 
1 5   LYS n 
1 6   LEU n 
1 7   PRO n 
1 8   ALA n 
1 9   LEU n 
1 10  ALA n 
1 11  TYR n 
1 12  ARG n 
1 13  SER n 
1 14  ALA n 
1 15  LYS n 
1 16  ASP n 
1 17  THR n 
1 18  GLY n 
1 19  GLU n 
1 20  SER n 
1 21  MET n 
1 22  THR n 
1 23  ASP n 
1 24  THR n 
1 25  PRO n 
1 26  TYR n 
1 27  ILE n 
1 28  ARG n 
1 29  PRO n 
1 30  ASP n 
1 31  MET n 
1 32  LYS n 
1 33  ALA n 
1 34  PHE n 
1 35  LEU n 
1 36  GLU n 
1 37  MET n 
1 38  MET n 
1 39  ALA n 
1 40  GLN n 
1 41  VAL n 
1 42  ASN n 
1 43  GLY n 
1 44  PRO n 
1 45  LYS n 
1 46  LEU n 
1 47  SER n 
1 48  GLU n 
1 49  MET n 
1 50  SER n 
1 51  LEU n 
1 52  ASP n 
1 53  GLU n 
1 54  ALA n 
1 55  ARG n 
1 56  ALA n 
1 57  SER n 
1 58  TYR n 
1 59  LEU n 
1 60  ALA n 
1 61  MET n 
1 62  HIS n 
1 63  ASN n 
1 64  LEU n 
1 65  ALA n 
1 66  ASP n 
1 67  ARG n 
1 68  PRO n 
1 69  ALA n 
1 70  ARG n 
1 71  ALA n 
1 72  LEU n 
1 73  PRO n 
1 74  VAL n 
1 75  ILE n 
1 76  ARG n 
1 77  ASP n 
1 78  LEU n 
1 79  SER n 
1 80  CYS n 
1 81  PRO n 
1 82  GLY n 
1 83  PRO n 
1 84  LYS n 
1 85  GLY n 
1 86  GLU n 
1 87  ILE n 
1 88  ALA n 
1 89  LEU n 
1 90  ARG n 
1 91  LEU n 
1 92  TYR n 
1 93  ASP n 
1 94  PRO n 
1 95  ARG n 
1 96  GLU n 
1 97  SER n 
1 98  ARG n 
1 99  ALA n 
1 100 GLY n 
1 101 PRO n 
1 102 THR n 
1 103 PRO n 
1 104 VAL n 
1 105 ILE n 
1 106 THR n 
1 107 PHE n 
1 108 PHE n 
1 109 HIS n 
1 110 GLY n 
1 111 GLY n 
1 112 GLY n 
1 113 PHE n 
1 114 VAL n 
1 115 ILE n 
1 116 GLY n 
1 117 ASP n 
1 118 LEU n 
1 119 ASP n 
1 120 THR n 
1 121 HIS n 
1 122 HIS n 
1 123 ALA n 
1 124 LEU n 
1 125 CYS n 
1 126 THR n 
1 127 GLU n 
1 128 ILE n 
1 129 ALA n 
1 130 ALA n 
1 131 LEU n 
1 132 MET n 
1 133 ASP n 
1 134 LEU n 
1 135 PRO n 
1 136 LEU n 
1 137 VAL n 
1 138 ALA n 
1 139 VAL n 
1 140 HIS n 
1 141 TYR n 
1 142 ALA n 
1 143 ARG n 
1 144 ALA n 
1 145 PRO n 
1 146 GLU n 
1 147 ALA n 
1 148 PRO n 
1 149 PHE n 
1 150 PRO n 
1 151 ALA n 
1 152 ALA n 
1 153 ILE n 
1 154 LEU n 
1 155 ASP n 
1 156 CYS n 
1 157 GLU n 
1 158 ALA n 
1 159 ALA n 
1 160 THR n 
1 161 ARG n 
1 162 TRP n 
1 163 ILE n 
1 164 ALA n 
1 165 SER n 
1 166 SER n 
1 167 PRO n 
1 168 ALA n 
1 169 GLU n 
1 170 LEU n 
1 171 GLY n 
1 172 LEU n 
1 173 THR n 
1 174 ALA n 
1 175 SER n 
1 176 GLY n 
1 177 ILE n 
1 178 ILE n 
1 179 THR n 
1 180 ILE n 
1 181 GLY n 
1 182 ASP n 
1 183 SER n 
1 184 ALA n 
1 185 GLY n 
1 186 GLY n 
1 187 ASN n 
1 188 ALA n 
1 189 THR n 
1 190 VAL n 
1 191 VAL n 
1 192 VAL n 
1 193 GLY n 
1 194 GLN n 
1 195 LEU n 
1 196 LEU n 
1 197 ALA n 
1 198 ALA n 
1 199 SER n 
1 200 PRO n 
1 201 ALA n 
1 202 ALA n 
1 203 VAL n 
1 204 PRO n 
1 205 VAL n 
1 206 VAL n 
1 207 LEU n 
1 208 GLN n 
1 209 VAL n 
1 210 PRO n 
1 211 ILE n 
1 212 PHE n 
1 213 PRO n 
1 214 LEU n 
1 215 VAL n 
1 216 ALA n 
1 217 ASP n 
1 218 ALA n 
1 219 VAL n 
1 220 SER n 
1 221 SER n 
1 222 GLU n 
1 223 SER n 
1 224 MET n 
1 225 ALA n 
1 226 ALA n 
1 227 PHE n 
1 228 SER n 
1 229 GLU n 
1 230 GLY n 
1 231 TYR n 
1 232 LEU n 
1 233 LEU n 
1 234 THR n 
1 235 ALA n 
1 236 GLU n 
1 237 THR n 
1 238 MET n 
1 239 ALA n 
1 240 PHE n 
1 241 PHE n 
1 242 ASP n 
1 243 ALA n 
1 244 ALA n 
1 245 TYR n 
1 246 GLY n 
1 247 ALA n 
1 248 ASP n 
1 249 ARG n 
1 250 SER n 
1 251 ASP n 
1 252 PRO n 
1 253 ARG n 
1 254 GLY n 
1 255 PHE n 
1 256 PRO n 
1 257 ILE n 
1 258 LEU n 
1 259 GLY n 
1 260 ARG n 
1 261 HIS n 
1 262 ASP n 
1 263 ASN n 
1 264 ALA n 
1 265 PRO n 
1 266 PRO n 
1 267 THR n 
1 268 ILE n 
1 269 VAL n 
1 270 VAL n 
1 271 THR n 
1 272 ALA n 
1 273 SER n 
1 274 LEU n 
1 275 ASP n 
1 276 PRO n 
1 277 ILE n 
1 278 ARG n 
1 279 ASP n 
1 280 SER n 
1 281 GLY n 
1 282 ARG n 
1 283 ALA n 
1 284 TYR n 
1 285 ALA n 
1 286 LYS n 
1 287 ALA n 
1 288 LEU n 
1 289 ILE n 
1 290 ASP n 
1 291 ALA n 
1 292 GLY n 
1 293 ARG n 
1 294 ASP n 
1 295 CYS n 
1 296 VAL n 
1 297 PHE n 
1 298 LEU n 
1 299 GLU n 
1 300 MET n 
1 301 ARG n 
1 302 GLY n 
1 303 VAL n 
1 304 THR n 
1 305 HIS n 
1 306 SER n 
1 307 PHE n 
1 308 THR n 
1 309 ASN n 
1 310 LEU n 
1 311 ARG n 
1 312 GLN n 
1 313 MET n 
1 314 VAL n 
1 315 PRO n 
1 316 SER n 
1 317 THR n 
1 318 GLN n 
1 319 ALA n 
1 320 ASP n 
1 321 LEU n 
1 322 GLU n 
1 323 ARG n 
1 324 VAL n 
1 325 ILE n 
1 326 ALA n 
1 327 ALA n 
1 328 MET n 
1 329 GLN n 
1 330 PHE n 
1 331 MET n 
1 332 LEU n 
1 333 ALA n 
1 334 ASN n 
1 335 PRO n 
1 336 ALA n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   336 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 poc14 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    'DSM 12079' 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Erythrobacter cryptus DSM 12079' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     1122970 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                               ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                             ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                        ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE                               ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE                              ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                        ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                                ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE                              ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER                                  ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE                             ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                                ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                                 ? 'C6 H15 N2 O2 1' 147.195 
MES non-polymer         . '2-(N-MORPHOLINO)-ETHANESULFONIC ACID' ? 'C6 H13 N O4 S'  195.237 
MET 'L-peptide linking' y METHIONINE                             ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE                          ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                                ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                                 ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                              ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                             ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                               ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                                 ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   ARG 2   2   ?   ?   ?   A . n 
A 1 3   LEU 3   3   ?   ?   ?   A . n 
A 1 4   ALA 4   4   ?   ?   ?   A . n 
A 1 5   LYS 5   5   ?   ?   ?   A . n 
A 1 6   LEU 6   6   ?   ?   ?   A . n 
A 1 7   PRO 7   7   ?   ?   ?   A . n 
A 1 8   ALA 8   8   ?   ?   ?   A . n 
A 1 9   LEU 9   9   ?   ?   ?   A . n 
A 1 10  ALA 10  10  ?   ?   ?   A . n 
A 1 11  TYR 11  11  ?   ?   ?   A . n 
A 1 12  ARG 12  12  ?   ?   ?   A . n 
A 1 13  SER 13  13  ?   ?   ?   A . n 
A 1 14  ALA 14  14  ?   ?   ?   A . n 
A 1 15  LYS 15  15  ?   ?   ?   A . n 
A 1 16  ASP 16  16  ?   ?   ?   A . n 
A 1 17  THR 17  17  ?   ?   ?   A . n 
A 1 18  GLY 18  18  ?   ?   ?   A . n 
A 1 19  GLU 19  19  ?   ?   ?   A . n 
A 1 20  SER 20  20  ?   ?   ?   A . n 
A 1 21  MET 21  21  ?   ?   ?   A . n 
A 1 22  THR 22  22  ?   ?   ?   A . n 
A 1 23  ASP 23  23  ?   ?   ?   A . n 
A 1 24  THR 24  24  24  THR THR A . n 
A 1 25  PRO 25  25  25  PRO PRO A . n 
A 1 26  TYR 26  26  26  TYR TYR A . n 
A 1 27  ILE 27  27  27  ILE ILE A . n 
A 1 28  ARG 28  28  28  ARG ARG A . n 
A 1 29  PRO 29  29  29  PRO PRO A . n 
A 1 30  ASP 30  30  30  ASP ASP A . n 
A 1 31  MET 31  31  31  MET MET A . n 
A 1 32  LYS 32  32  32  LYS LYS A . n 
A 1 33  ALA 33  33  33  ALA ALA A . n 
A 1 34  PHE 34  34  34  PHE PHE A . n 
A 1 35  LEU 35  35  35  LEU LEU A . n 
A 1 36  GLU 36  36  36  GLU GLU A . n 
A 1 37  MET 37  37  37  MET MET A . n 
A 1 38  MET 38  38  38  MET MET A . n 
A 1 39  ALA 39  39  39  ALA ALA A . n 
A 1 40  GLN 40  40  40  GLN GLN A . n 
A 1 41  VAL 41  41  41  VAL VAL A . n 
A 1 42  ASN 42  42  42  ASN ASN A . n 
A 1 43  GLY 43  43  43  GLY GLY A . n 
A 1 44  PRO 44  44  44  PRO PRO A . n 
A 1 45  LYS 45  45  45  LYS LYS A . n 
A 1 46  LEU 46  46  46  LEU LEU A . n 
A 1 47  SER 47  47  47  SER SER A . n 
A 1 48  GLU 48  48  48  GLU GLU A . n 
A 1 49  MET 49  49  49  MET MET A . n 
A 1 50  SER 50  50  50  SER SER A . n 
A 1 51  LEU 51  51  51  LEU LEU A . n 
A 1 52  ASP 52  52  52  ASP ASP A . n 
A 1 53  GLU 53  53  53  GLU GLU A . n 
A 1 54  ALA 54  54  54  ALA ALA A . n 
A 1 55  ARG 55  55  55  ARG ARG A . n 
A 1 56  ALA 56  56  56  ALA ALA A . n 
A 1 57  SER 57  57  57  SER SER A . n 
A 1 58  TYR 58  58  58  TYR TYR A . n 
A 1 59  LEU 59  59  59  LEU LEU A . n 
A 1 60  ALA 60  60  60  ALA ALA A . n 
A 1 61  MET 61  61  61  MET MET A . n 
A 1 62  HIS 62  62  62  HIS HIS A . n 
A 1 63  ASN 63  63  63  ASN ASN A . n 
A 1 64  LEU 64  64  64  LEU LEU A . n 
A 1 65  ALA 65  65  65  ALA ALA A . n 
A 1 66  ASP 66  66  66  ASP ASP A . n 
A 1 67  ARG 67  67  67  ARG ARG A . n 
A 1 68  PRO 68  68  68  PRO PRO A . n 
A 1 69  ALA 69  69  69  ALA ALA A . n 
A 1 70  ARG 70  70  70  ARG ARG A . n 
A 1 71  ALA 71  71  71  ALA ALA A . n 
A 1 72  LEU 72  72  72  LEU LEU A . n 
A 1 73  PRO 73  73  73  PRO PRO A . n 
A 1 74  VAL 74  74  74  VAL VAL A . n 
A 1 75  ILE 75  75  75  ILE ILE A . n 
A 1 76  ARG 76  76  76  ARG ARG A . n 
A 1 77  ASP 77  77  77  ASP ASP A . n 
A 1 78  LEU 78  78  78  LEU LEU A . n 
A 1 79  SER 79  79  79  SER SER A . n 
A 1 80  CYS 80  80  80  CYS CYS A . n 
A 1 81  PRO 81  81  81  PRO PRO A . n 
A 1 82  GLY 82  82  82  GLY GLY A . n 
A 1 83  PRO 83  83  83  PRO PRO A . n 
A 1 84  LYS 84  84  84  LYS LYS A . n 
A 1 85  GLY 85  85  85  GLY GLY A . n 
A 1 86  GLU 86  86  86  GLU GLU A . n 
A 1 87  ILE 87  87  87  ILE ILE A . n 
A 1 88  ALA 88  88  88  ALA ALA A . n 
A 1 89  LEU 89  89  89  LEU LEU A . n 
A 1 90  ARG 90  90  90  ARG ARG A . n 
A 1 91  LEU 91  91  91  LEU LEU A . n 
A 1 92  TYR 92  92  92  TYR TYR A . n 
A 1 93  ASP 93  93  93  ASP ASP A . n 
A 1 94  PRO 94  94  94  PRO PRO A . n 
A 1 95  ARG 95  95  95  ARG ARG A . n 
A 1 96  GLU 96  96  96  GLU GLU A . n 
A 1 97  SER 97  97  97  SER SER A . n 
A 1 98  ARG 98  98  98  ARG ARG A . n 
A 1 99  ALA 99  99  99  ALA ALA A . n 
A 1 100 GLY 100 100 100 GLY GLY A . n 
A 1 101 PRO 101 101 101 PRO PRO A . n 
A 1 102 THR 102 102 102 THR THR A . n 
A 1 103 PRO 103 103 103 PRO PRO A . n 
A 1 104 VAL 104 104 104 VAL VAL A . n 
A 1 105 ILE 105 105 105 ILE ILE A . n 
A 1 106 THR 106 106 106 THR THR A . n 
A 1 107 PHE 107 107 107 PHE PHE A . n 
A 1 108 PHE 108 108 108 PHE PHE A . n 
A 1 109 HIS 109 109 109 HIS HIS A . n 
A 1 110 GLY 110 110 110 GLY GLY A . n 
A 1 111 GLY 111 111 111 GLY GLY A . n 
A 1 112 GLY 112 112 112 GLY GLY A . n 
A 1 113 PHE 113 113 113 PHE PHE A . n 
A 1 114 VAL 114 114 114 VAL VAL A . n 
A 1 115 ILE 115 115 115 ILE ILE A . n 
A 1 116 GLY 116 116 116 GLY GLY A . n 
A 1 117 ASP 117 117 117 ASP ASP A . n 
A 1 118 LEU 118 118 118 LEU LEU A . n 
A 1 119 ASP 119 119 119 ASP ASP A . n 
A 1 120 THR 120 120 120 THR THR A . n 
A 1 121 HIS 121 121 121 HIS HIS A . n 
A 1 122 HIS 122 122 122 HIS HIS A . n 
A 1 123 ALA 123 123 123 ALA ALA A . n 
A 1 124 LEU 124 124 124 LEU LEU A . n 
A 1 125 CYS 125 125 125 CYS CYS A . n 
A 1 126 THR 126 126 126 THR THR A . n 
A 1 127 GLU 127 127 127 GLU GLU A . n 
A 1 128 ILE 128 128 128 ILE ILE A . n 
A 1 129 ALA 129 129 129 ALA ALA A . n 
A 1 130 ALA 130 130 130 ALA ALA A . n 
A 1 131 LEU 131 131 131 LEU LEU A . n 
A 1 132 MET 132 132 132 MET MET A . n 
A 1 133 ASP 133 133 133 ASP ASP A . n 
A 1 134 LEU 134 134 134 LEU LEU A . n 
A 1 135 PRO 135 135 135 PRO PRO A . n 
A 1 136 LEU 136 136 136 LEU LEU A . n 
A 1 137 VAL 137 137 137 VAL VAL A . n 
A 1 138 ALA 138 138 138 ALA ALA A . n 
A 1 139 VAL 139 139 139 VAL VAL A . n 
A 1 140 HIS 140 140 140 HIS HIS A . n 
A 1 141 TYR 141 141 141 TYR TYR A . n 
A 1 142 ALA 142 142 142 ALA ALA A . n 
A 1 143 ARG 143 143 143 ARG ARG A . n 
A 1 144 ALA 144 144 144 ALA ALA A . n 
A 1 145 PRO 145 145 145 PRO PRO A . n 
A 1 146 GLU 146 146 146 GLU GLU A . n 
A 1 147 ALA 147 147 147 ALA ALA A . n 
A 1 148 PRO 148 148 148 PRO PRO A . n 
A 1 149 PHE 149 149 149 PHE PHE A . n 
A 1 150 PRO 150 150 150 PRO PRO A . n 
A 1 151 ALA 151 151 151 ALA ALA A . n 
A 1 152 ALA 152 152 152 ALA ALA A . n 
A 1 153 ILE 153 153 153 ILE ILE A . n 
A 1 154 LEU 154 154 154 LEU LEU A . n 
A 1 155 ASP 155 155 155 ASP ASP A . n 
A 1 156 CYS 156 156 156 CYS CYS A . n 
A 1 157 GLU 157 157 157 GLU GLU A . n 
A 1 158 ALA 158 158 158 ALA ALA A . n 
A 1 159 ALA 159 159 159 ALA ALA A . n 
A 1 160 THR 160 160 160 THR THR A . n 
A 1 161 ARG 161 161 161 ARG ARG A . n 
A 1 162 TRP 162 162 162 TRP TRP A . n 
A 1 163 ILE 163 163 163 ILE ILE A . n 
A 1 164 ALA 164 164 164 ALA ALA A . n 
A 1 165 SER 165 165 165 SER SER A . n 
A 1 166 SER 166 166 166 SER SER A . n 
A 1 167 PRO 167 167 167 PRO PRO A . n 
A 1 168 ALA 168 168 168 ALA ALA A . n 
A 1 169 GLU 169 169 169 GLU GLU A . n 
A 1 170 LEU 170 170 170 LEU LEU A . n 
A 1 171 GLY 171 171 171 GLY GLY A . n 
A 1 172 LEU 172 172 172 LEU LEU A . n 
A 1 173 THR 173 173 173 THR THR A . n 
A 1 174 ALA 174 174 174 ALA ALA A . n 
A 1 175 SER 175 175 175 SER SER A . n 
A 1 176 GLY 176 176 176 GLY GLY A . n 
A 1 177 ILE 177 177 177 ILE ILE A . n 
A 1 178 ILE 178 178 178 ILE ILE A . n 
A 1 179 THR 179 179 179 THR THR A . n 
A 1 180 ILE 180 180 180 ILE ILE A . n 
A 1 181 GLY 181 181 181 GLY GLY A . n 
A 1 182 ASP 182 182 182 ASP ASP A . n 
A 1 183 SER 183 183 183 SER SER A . n 
A 1 184 ALA 184 184 184 ALA ALA A . n 
A 1 185 GLY 185 185 185 GLY GLY A . n 
A 1 186 GLY 186 186 186 GLY GLY A . n 
A 1 187 ASN 187 187 187 ASN ASN A . n 
A 1 188 ALA 188 188 188 ALA ALA A . n 
A 1 189 THR 189 189 189 THR THR A . n 
A 1 190 VAL 190 190 190 VAL VAL A . n 
A 1 191 VAL 191 191 191 VAL VAL A . n 
A 1 192 VAL 192 192 192 VAL VAL A . n 
A 1 193 GLY 193 193 193 GLY GLY A . n 
A 1 194 GLN 194 194 194 GLN GLN A . n 
A 1 195 LEU 195 195 195 LEU LEU A . n 
A 1 196 LEU 196 196 196 LEU LEU A . n 
A 1 197 ALA 197 197 197 ALA ALA A . n 
A 1 198 ALA 198 198 198 ALA ALA A . n 
A 1 199 SER 199 199 199 SER SER A . n 
A 1 200 PRO 200 200 200 PRO PRO A . n 
A 1 201 ALA 201 201 201 ALA ALA A . n 
A 1 202 ALA 202 202 202 ALA ALA A . n 
A 1 203 VAL 203 203 203 VAL VAL A . n 
A 1 204 PRO 204 204 204 PRO PRO A . n 
A 1 205 VAL 205 205 205 VAL VAL A . n 
A 1 206 VAL 206 206 206 VAL VAL A . n 
A 1 207 LEU 207 207 207 LEU LEU A . n 
A 1 208 GLN 208 208 208 GLN GLN A . n 
A 1 209 VAL 209 209 209 VAL VAL A . n 
A 1 210 PRO 210 210 210 PRO PRO A . n 
A 1 211 ILE 211 211 211 ILE ILE A . n 
A 1 212 PHE 212 212 212 PHE PHE A . n 
A 1 213 PRO 213 213 213 PRO PRO A . n 
A 1 214 LEU 214 214 214 LEU LEU A . n 
A 1 215 VAL 215 215 215 VAL VAL A . n 
A 1 216 ALA 216 216 216 ALA ALA A . n 
A 1 217 ASP 217 217 217 ASP ASP A . n 
A 1 218 ALA 218 218 218 ALA ALA A . n 
A 1 219 VAL 219 219 219 VAL VAL A . n 
A 1 220 SER 220 220 220 SER SER A . n 
A 1 221 SER 221 221 221 SER SER A . n 
A 1 222 GLU 222 222 222 GLU GLU A . n 
A 1 223 SER 223 223 223 SER SER A . n 
A 1 224 MET 224 224 224 MET MET A . n 
A 1 225 ALA 225 225 225 ALA ALA A . n 
A 1 226 ALA 226 226 226 ALA ALA A . n 
A 1 227 PHE 227 227 227 PHE PHE A . n 
A 1 228 SER 228 228 228 SER SER A . n 
A 1 229 GLU 229 229 229 GLU GLU A . n 
A 1 230 GLY 230 230 230 GLY GLY A . n 
A 1 231 TYR 231 231 231 TYR TYR A . n 
A 1 232 LEU 232 232 232 LEU LEU A . n 
A 1 233 LEU 233 233 233 LEU LEU A . n 
A 1 234 THR 234 234 234 THR THR A . n 
A 1 235 ALA 235 235 235 ALA ALA A . n 
A 1 236 GLU 236 236 236 GLU GLU A . n 
A 1 237 THR 237 237 237 THR THR A . n 
A 1 238 MET 238 238 238 MET MET A . n 
A 1 239 ALA 239 239 239 ALA ALA A . n 
A 1 240 PHE 240 240 240 PHE PHE A . n 
A 1 241 PHE 241 241 241 PHE PHE A . n 
A 1 242 ASP 242 242 242 ASP ASP A . n 
A 1 243 ALA 243 243 243 ALA ALA A . n 
A 1 244 ALA 244 244 244 ALA ALA A . n 
A 1 245 TYR 245 245 245 TYR TYR A . n 
A 1 246 GLY 246 246 246 GLY GLY A . n 
A 1 247 ALA 247 247 247 ALA ALA A . n 
A 1 248 ASP 248 248 248 ASP ASP A . n 
A 1 249 ARG 249 249 249 ARG ARG A . n 
A 1 250 SER 250 250 250 SER SER A . n 
A 1 251 ASP 251 251 251 ASP ASP A . n 
A 1 252 PRO 252 252 252 PRO PRO A . n 
A 1 253 ARG 253 253 253 ARG ARG A . n 
A 1 254 GLY 254 254 254 GLY GLY A . n 
A 1 255 PHE 255 255 255 PHE PHE A . n 
A 1 256 PRO 256 256 256 PRO PRO A . n 
A 1 257 ILE 257 257 257 ILE ILE A . n 
A 1 258 LEU 258 258 258 LEU LEU A . n 
A 1 259 GLY 259 259 259 GLY GLY A . n 
A 1 260 ARG 260 260 260 ARG ARG A . n 
A 1 261 HIS 261 261 261 HIS HIS A . n 
A 1 262 ASP 262 262 262 ASP ASP A . n 
A 1 263 ASN 263 263 263 ASN ASN A . n 
A 1 264 ALA 264 264 264 ALA ALA A . n 
A 1 265 PRO 265 265 265 PRO PRO A . n 
A 1 266 PRO 266 266 266 PRO PRO A . n 
A 1 267 THR 267 267 267 THR THR A . n 
A 1 268 ILE 268 268 268 ILE ILE A . n 
A 1 269 VAL 269 269 269 VAL VAL A . n 
A 1 270 VAL 270 270 270 VAL VAL A . n 
A 1 271 THR 271 271 271 THR THR A . n 
A 1 272 ALA 272 272 272 ALA ALA A . n 
A 1 273 SER 273 273 273 SER SER A . n 
A 1 274 LEU 274 274 274 LEU LEU A . n 
A 1 275 ASP 275 275 275 ASP ASP A . n 
A 1 276 PRO 276 276 276 PRO PRO A . n 
A 1 277 ILE 277 277 277 ILE ILE A . n 
A 1 278 ARG 278 278 278 ARG ARG A . n 
A 1 279 ASP 279 279 279 ASP ASP A . n 
A 1 280 SER 280 280 280 SER SER A . n 
A 1 281 GLY 281 281 281 GLY GLY A . n 
A 1 282 ARG 282 282 282 ARG ARG A . n 
A 1 283 ALA 283 283 283 ALA ALA A . n 
A 1 284 TYR 284 284 284 TYR TYR A . n 
A 1 285 ALA 285 285 285 ALA ALA A . n 
A 1 286 LYS 286 286 286 LYS LYS A . n 
A 1 287 ALA 287 287 287 ALA ALA A . n 
A 1 288 LEU 288 288 288 LEU LEU A . n 
A 1 289 ILE 289 289 289 ILE ILE A . n 
A 1 290 ASP 290 290 290 ASP ASP A . n 
A 1 291 ALA 291 291 291 ALA ALA A . n 
A 1 292 GLY 292 292 292 GLY GLY A . n 
A 1 293 ARG 293 293 293 ARG ARG A . n 
A 1 294 ASP 294 294 294 ASP ASP A . n 
A 1 295 CYS 295 295 295 CYS CYS A . n 
A 1 296 VAL 296 296 296 VAL VAL A . n 
A 1 297 PHE 297 297 297 PHE PHE A . n 
A 1 298 LEU 298 298 298 LEU LEU A . n 
A 1 299 GLU 299 299 299 GLU GLU A . n 
A 1 300 MET 300 300 300 MET MET A . n 
A 1 301 ARG 301 301 301 ARG ARG A . n 
A 1 302 GLY 302 302 302 GLY GLY A . n 
A 1 303 VAL 303 303 303 VAL VAL A . n 
A 1 304 THR 304 304 304 THR THR A . n 
A 1 305 HIS 305 305 305 HIS HIS A . n 
A 1 306 SER 306 306 306 SER SER A . n 
A 1 307 PHE 307 307 307 PHE PHE A . n 
A 1 308 THR 308 308 308 THR THR A . n 
A 1 309 ASN 309 309 309 ASN ASN A . n 
A 1 310 LEU 310 310 310 LEU LEU A . n 
A 1 311 ARG 311 311 311 ARG ARG A . n 
A 1 312 GLN 312 312 312 GLN GLN A . n 
A 1 313 MET 313 313 313 MET MET A . n 
A 1 314 VAL 314 314 314 VAL VAL A . n 
A 1 315 PRO 315 315 315 PRO PRO A . n 
A 1 316 SER 316 316 316 SER SER A . n 
A 1 317 THR 317 317 317 THR THR A . n 
A 1 318 GLN 318 318 318 GLN GLN A . n 
A 1 319 ALA 319 319 319 ALA ALA A . n 
A 1 320 ASP 320 320 320 ASP ASP A . n 
A 1 321 LEU 321 321 321 LEU LEU A . n 
A 1 322 GLU 322 322 322 GLU GLU A . n 
A 1 323 ARG 323 323 323 ARG ARG A . n 
A 1 324 VAL 324 324 324 VAL VAL A . n 
A 1 325 ILE 325 325 325 ILE ILE A . n 
A 1 326 ALA 326 326 326 ALA ALA A . n 
A 1 327 ALA 327 327 327 ALA ALA A . n 
A 1 328 MET 328 328 328 MET MET A . n 
A 1 329 GLN 329 329 329 GLN GLN A . n 
A 1 330 PHE 330 330 330 PHE PHE A . n 
A 1 331 MET 331 331 331 MET MET A . n 
A 1 332 LEU 332 332 332 LEU LEU A . n 
A 1 333 ALA 333 333 333 ALA ALA A . n 
A 1 334 ASN 334 334 334 ASN ASN A . n 
A 1 335 PRO 335 335 335 PRO PRO A . n 
A 1 336 ALA 336 336 336 ALA ALA A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   ARG 2   2   ?   ?   ?   B . n 
B 1 3   LEU 3   3   ?   ?   ?   B . n 
B 1 4   ALA 4   4   ?   ?   ?   B . n 
B 1 5   LYS 5   5   ?   ?   ?   B . n 
B 1 6   LEU 6   6   ?   ?   ?   B . n 
B 1 7   PRO 7   7   ?   ?   ?   B . n 
B 1 8   ALA 8   8   ?   ?   ?   B . n 
B 1 9   LEU 9   9   ?   ?   ?   B . n 
B 1 10  ALA 10  10  ?   ?   ?   B . n 
B 1 11  TYR 11  11  ?   ?   ?   B . n 
B 1 12  ARG 12  12  ?   ?   ?   B . n 
B 1 13  SER 13  13  ?   ?   ?   B . n 
B 1 14  ALA 14  14  ?   ?   ?   B . n 
B 1 15  LYS 15  15  ?   ?   ?   B . n 
B 1 16  ASP 16  16  ?   ?   ?   B . n 
B 1 17  THR 17  17  ?   ?   ?   B . n 
B 1 18  GLY 18  18  ?   ?   ?   B . n 
B 1 19  GLU 19  19  ?   ?   ?   B . n 
B 1 20  SER 20  20  ?   ?   ?   B . n 
B 1 21  MET 21  21  ?   ?   ?   B . n 
B 1 22  THR 22  22  ?   ?   ?   B . n 
B 1 23  ASP 23  23  ?   ?   ?   B . n 
B 1 24  THR 24  24  24  THR THR B . n 
B 1 25  PRO 25  25  25  PRO PRO B . n 
B 1 26  TYR 26  26  26  TYR TYR B . n 
B 1 27  ILE 27  27  27  ILE ILE B . n 
B 1 28  ARG 28  28  28  ARG ARG B . n 
B 1 29  PRO 29  29  29  PRO PRO B . n 
B 1 30  ASP 30  30  30  ASP ASP B . n 
B 1 31  MET 31  31  31  MET MET B . n 
B 1 32  LYS 32  32  32  LYS LYS B . n 
B 1 33  ALA 33  33  33  ALA ALA B . n 
B 1 34  PHE 34  34  34  PHE PHE B . n 
B 1 35  LEU 35  35  35  LEU LEU B . n 
B 1 36  GLU 36  36  36  GLU GLU B . n 
B 1 37  MET 37  37  37  MET MET B . n 
B 1 38  MET 38  38  38  MET MET B . n 
B 1 39  ALA 39  39  39  ALA ALA B . n 
B 1 40  GLN 40  40  40  GLN GLN B . n 
B 1 41  VAL 41  41  41  VAL VAL B . n 
B 1 42  ASN 42  42  42  ASN ASN B . n 
B 1 43  GLY 43  43  43  GLY GLY B . n 
B 1 44  PRO 44  44  44  PRO PRO B . n 
B 1 45  LYS 45  45  45  LYS LYS B . n 
B 1 46  LEU 46  46  46  LEU LEU B . n 
B 1 47  SER 47  47  47  SER SER B . n 
B 1 48  GLU 48  48  48  GLU GLU B . n 
B 1 49  MET 49  49  49  MET MET B . n 
B 1 50  SER 50  50  50  SER SER B . n 
B 1 51  LEU 51  51  51  LEU LEU B . n 
B 1 52  ASP 52  52  52  ASP ASP B . n 
B 1 53  GLU 53  53  53  GLU GLU B . n 
B 1 54  ALA 54  54  54  ALA ALA B . n 
B 1 55  ARG 55  55  55  ARG ARG B . n 
B 1 56  ALA 56  56  56  ALA ALA B . n 
B 1 57  SER 57  57  57  SER SER B . n 
B 1 58  TYR 58  58  58  TYR TYR B . n 
B 1 59  LEU 59  59  59  LEU LEU B . n 
B 1 60  ALA 60  60  60  ALA ALA B . n 
B 1 61  MET 61  61  61  MET MET B . n 
B 1 62  HIS 62  62  62  HIS HIS B . n 
B 1 63  ASN 63  63  63  ASN ASN B . n 
B 1 64  LEU 64  64  64  LEU LEU B . n 
B 1 65  ALA 65  65  65  ALA ALA B . n 
B 1 66  ASP 66  66  66  ASP ASP B . n 
B 1 67  ARG 67  67  67  ARG ARG B . n 
B 1 68  PRO 68  68  68  PRO PRO B . n 
B 1 69  ALA 69  69  69  ALA ALA B . n 
B 1 70  ARG 70  70  70  ARG ARG B . n 
B 1 71  ALA 71  71  71  ALA ALA B . n 
B 1 72  LEU 72  72  72  LEU LEU B . n 
B 1 73  PRO 73  73  73  PRO PRO B . n 
B 1 74  VAL 74  74  74  VAL VAL B . n 
B 1 75  ILE 75  75  75  ILE ILE B . n 
B 1 76  ARG 76  76  76  ARG ARG B . n 
B 1 77  ASP 77  77  77  ASP ASP B . n 
B 1 78  LEU 78  78  78  LEU LEU B . n 
B 1 79  SER 79  79  79  SER SER B . n 
B 1 80  CYS 80  80  80  CYS CYS B . n 
B 1 81  PRO 81  81  81  PRO PRO B . n 
B 1 82  GLY 82  82  82  GLY GLY B . n 
B 1 83  PRO 83  83  83  PRO PRO B . n 
B 1 84  LYS 84  84  84  LYS LYS B . n 
B 1 85  GLY 85  85  85  GLY GLY B . n 
B 1 86  GLU 86  86  86  GLU GLU B . n 
B 1 87  ILE 87  87  87  ILE ILE B . n 
B 1 88  ALA 88  88  88  ALA ALA B . n 
B 1 89  LEU 89  89  89  LEU LEU B . n 
B 1 90  ARG 90  90  90  ARG ARG B . n 
B 1 91  LEU 91  91  91  LEU LEU B . n 
B 1 92  TYR 92  92  92  TYR TYR B . n 
B 1 93  ASP 93  93  93  ASP ASP B . n 
B 1 94  PRO 94  94  94  PRO PRO B . n 
B 1 95  ARG 95  95  95  ARG ARG B . n 
B 1 96  GLU 96  96  96  GLU GLU B . n 
B 1 97  SER 97  97  97  SER SER B . n 
B 1 98  ARG 98  98  98  ARG ARG B . n 
B 1 99  ALA 99  99  ?   ?   ?   B . n 
B 1 100 GLY 100 100 100 GLY GLY B . n 
B 1 101 PRO 101 101 101 PRO PRO B . n 
B 1 102 THR 102 102 102 THR THR B . n 
B 1 103 PRO 103 103 103 PRO PRO B . n 
B 1 104 VAL 104 104 104 VAL VAL B . n 
B 1 105 ILE 105 105 105 ILE ILE B . n 
B 1 106 THR 106 106 106 THR THR B . n 
B 1 107 PHE 107 107 107 PHE PHE B . n 
B 1 108 PHE 108 108 108 PHE PHE B . n 
B 1 109 HIS 109 109 109 HIS HIS B . n 
B 1 110 GLY 110 110 110 GLY GLY B . n 
B 1 111 GLY 111 111 111 GLY GLY B . n 
B 1 112 GLY 112 112 112 GLY GLY B . n 
B 1 113 PHE 113 113 113 PHE PHE B . n 
B 1 114 VAL 114 114 114 VAL VAL B . n 
B 1 115 ILE 115 115 115 ILE ILE B . n 
B 1 116 GLY 116 116 116 GLY GLY B . n 
B 1 117 ASP 117 117 117 ASP ASP B . n 
B 1 118 LEU 118 118 118 LEU LEU B . n 
B 1 119 ASP 119 119 119 ASP ASP B . n 
B 1 120 THR 120 120 120 THR THR B . n 
B 1 121 HIS 121 121 121 HIS HIS B . n 
B 1 122 HIS 122 122 122 HIS HIS B . n 
B 1 123 ALA 123 123 123 ALA ALA B . n 
B 1 124 LEU 124 124 124 LEU LEU B . n 
B 1 125 CYS 125 125 125 CYS CYS B . n 
B 1 126 THR 126 126 126 THR THR B . n 
B 1 127 GLU 127 127 127 GLU GLU B . n 
B 1 128 ILE 128 128 128 ILE ILE B . n 
B 1 129 ALA 129 129 129 ALA ALA B . n 
B 1 130 ALA 130 130 130 ALA ALA B . n 
B 1 131 LEU 131 131 131 LEU LEU B . n 
B 1 132 MET 132 132 132 MET MET B . n 
B 1 133 ASP 133 133 133 ASP ASP B . n 
B 1 134 LEU 134 134 134 LEU LEU B . n 
B 1 135 PRO 135 135 135 PRO PRO B . n 
B 1 136 LEU 136 136 136 LEU LEU B . n 
B 1 137 VAL 137 137 137 VAL VAL B . n 
B 1 138 ALA 138 138 138 ALA ALA B . n 
B 1 139 VAL 139 139 139 VAL VAL B . n 
B 1 140 HIS 140 140 140 HIS HIS B . n 
B 1 141 TYR 141 141 141 TYR TYR B . n 
B 1 142 ALA 142 142 142 ALA ALA B . n 
B 1 143 ARG 143 143 143 ARG ARG B . n 
B 1 144 ALA 144 144 144 ALA ALA B . n 
B 1 145 PRO 145 145 145 PRO PRO B . n 
B 1 146 GLU 146 146 146 GLU GLU B . n 
B 1 147 ALA 147 147 147 ALA ALA B . n 
B 1 148 PRO 148 148 148 PRO PRO B . n 
B 1 149 PHE 149 149 149 PHE PHE B . n 
B 1 150 PRO 150 150 150 PRO PRO B . n 
B 1 151 ALA 151 151 151 ALA ALA B . n 
B 1 152 ALA 152 152 152 ALA ALA B . n 
B 1 153 ILE 153 153 153 ILE ILE B . n 
B 1 154 LEU 154 154 154 LEU LEU B . n 
B 1 155 ASP 155 155 155 ASP ASP B . n 
B 1 156 CYS 156 156 156 CYS CYS B . n 
B 1 157 GLU 157 157 157 GLU GLU B . n 
B 1 158 ALA 158 158 158 ALA ALA B . n 
B 1 159 ALA 159 159 159 ALA ALA B . n 
B 1 160 THR 160 160 160 THR THR B . n 
B 1 161 ARG 161 161 161 ARG ARG B . n 
B 1 162 TRP 162 162 162 TRP TRP B . n 
B 1 163 ILE 163 163 163 ILE ILE B . n 
B 1 164 ALA 164 164 164 ALA ALA B . n 
B 1 165 SER 165 165 165 SER SER B . n 
B 1 166 SER 166 166 166 SER SER B . n 
B 1 167 PRO 167 167 167 PRO PRO B . n 
B 1 168 ALA 168 168 168 ALA ALA B . n 
B 1 169 GLU 169 169 169 GLU GLU B . n 
B 1 170 LEU 170 170 170 LEU LEU B . n 
B 1 171 GLY 171 171 171 GLY GLY B . n 
B 1 172 LEU 172 172 172 LEU LEU B . n 
B 1 173 THR 173 173 173 THR THR B . n 
B 1 174 ALA 174 174 174 ALA ALA B . n 
B 1 175 SER 175 175 175 SER SER B . n 
B 1 176 GLY 176 176 176 GLY GLY B . n 
B 1 177 ILE 177 177 177 ILE ILE B . n 
B 1 178 ILE 178 178 178 ILE ILE B . n 
B 1 179 THR 179 179 179 THR THR B . n 
B 1 180 ILE 180 180 180 ILE ILE B . n 
B 1 181 GLY 181 181 181 GLY GLY B . n 
B 1 182 ASP 182 182 182 ASP ASP B . n 
B 1 183 SER 183 183 183 SER SER B . n 
B 1 184 ALA 184 184 184 ALA ALA B . n 
B 1 185 GLY 185 185 185 GLY GLY B . n 
B 1 186 GLY 186 186 186 GLY GLY B . n 
B 1 187 ASN 187 187 187 ASN ASN B . n 
B 1 188 ALA 188 188 188 ALA ALA B . n 
B 1 189 THR 189 189 189 THR THR B . n 
B 1 190 VAL 190 190 190 VAL VAL B . n 
B 1 191 VAL 191 191 191 VAL VAL B . n 
B 1 192 VAL 192 192 192 VAL VAL B . n 
B 1 193 GLY 193 193 193 GLY GLY B . n 
B 1 194 GLN 194 194 194 GLN GLN B . n 
B 1 195 LEU 195 195 195 LEU LEU B . n 
B 1 196 LEU 196 196 196 LEU LEU B . n 
B 1 197 ALA 197 197 197 ALA ALA B . n 
B 1 198 ALA 198 198 198 ALA ALA B . n 
B 1 199 SER 199 199 199 SER SER B . n 
B 1 200 PRO 200 200 200 PRO PRO B . n 
B 1 201 ALA 201 201 201 ALA ALA B . n 
B 1 202 ALA 202 202 202 ALA ALA B . n 
B 1 203 VAL 203 203 203 VAL VAL B . n 
B 1 204 PRO 204 204 204 PRO PRO B . n 
B 1 205 VAL 205 205 205 VAL VAL B . n 
B 1 206 VAL 206 206 206 VAL VAL B . n 
B 1 207 LEU 207 207 207 LEU LEU B . n 
B 1 208 GLN 208 208 208 GLN GLN B . n 
B 1 209 VAL 209 209 209 VAL VAL B . n 
B 1 210 PRO 210 210 210 PRO PRO B . n 
B 1 211 ILE 211 211 211 ILE ILE B . n 
B 1 212 PHE 212 212 212 PHE PHE B . n 
B 1 213 PRO 213 213 213 PRO PRO B . n 
B 1 214 LEU 214 214 214 LEU LEU B . n 
B 1 215 VAL 215 215 215 VAL VAL B . n 
B 1 216 ALA 216 216 216 ALA ALA B . n 
B 1 217 ASP 217 217 217 ASP ASP B . n 
B 1 218 ALA 218 218 218 ALA ALA B . n 
B 1 219 VAL 219 219 219 VAL VAL B . n 
B 1 220 SER 220 220 220 SER SER B . n 
B 1 221 SER 221 221 221 SER SER B . n 
B 1 222 GLU 222 222 222 GLU GLU B . n 
B 1 223 SER 223 223 223 SER SER B . n 
B 1 224 MET 224 224 224 MET MET B . n 
B 1 225 ALA 225 225 225 ALA ALA B . n 
B 1 226 ALA 226 226 226 ALA ALA B . n 
B 1 227 PHE 227 227 227 PHE PHE B . n 
B 1 228 SER 228 228 228 SER SER B . n 
B 1 229 GLU 229 229 229 GLU GLU B . n 
B 1 230 GLY 230 230 230 GLY GLY B . n 
B 1 231 TYR 231 231 231 TYR TYR B . n 
B 1 232 LEU 232 232 232 LEU LEU B . n 
B 1 233 LEU 233 233 233 LEU LEU B . n 
B 1 234 THR 234 234 234 THR THR B . n 
B 1 235 ALA 235 235 235 ALA ALA B . n 
B 1 236 GLU 236 236 236 GLU GLU B . n 
B 1 237 THR 237 237 237 THR THR B . n 
B 1 238 MET 238 238 238 MET MET B . n 
B 1 239 ALA 239 239 239 ALA ALA B . n 
B 1 240 PHE 240 240 240 PHE PHE B . n 
B 1 241 PHE 241 241 241 PHE PHE B . n 
B 1 242 ASP 242 242 242 ASP ASP B . n 
B 1 243 ALA 243 243 243 ALA ALA B . n 
B 1 244 ALA 244 244 244 ALA ALA B . n 
B 1 245 TYR 245 245 245 TYR TYR B . n 
B 1 246 GLY 246 246 246 GLY GLY B . n 
B 1 247 ALA 247 247 247 ALA ALA B . n 
B 1 248 ASP 248 248 248 ASP ASP B . n 
B 1 249 ARG 249 249 249 ARG ARG B . n 
B 1 250 SER 250 250 250 SER SER B . n 
B 1 251 ASP 251 251 251 ASP ASP B . n 
B 1 252 PRO 252 252 252 PRO PRO B . n 
B 1 253 ARG 253 253 253 ARG ARG B . n 
B 1 254 GLY 254 254 254 GLY GLY B . n 
B 1 255 PHE 255 255 255 PHE PHE B . n 
B 1 256 PRO 256 256 256 PRO PRO B . n 
B 1 257 ILE 257 257 257 ILE ILE B . n 
B 1 258 LEU 258 258 258 LEU LEU B . n 
B 1 259 GLY 259 259 259 GLY GLY B . n 
B 1 260 ARG 260 260 260 ARG ARG B . n 
B 1 261 HIS 261 261 261 HIS HIS B . n 
B 1 262 ASP 262 262 262 ASP ASP B . n 
B 1 263 ASN 263 263 263 ASN ASN B . n 
B 1 264 ALA 264 264 264 ALA ALA B . n 
B 1 265 PRO 265 265 265 PRO PRO B . n 
B 1 266 PRO 266 266 266 PRO PRO B . n 
B 1 267 THR 267 267 267 THR THR B . n 
B 1 268 ILE 268 268 268 ILE ILE B . n 
B 1 269 VAL 269 269 269 VAL VAL B . n 
B 1 270 VAL 270 270 270 VAL VAL B . n 
B 1 271 THR 271 271 271 THR THR B . n 
B 1 272 ALA 272 272 272 ALA ALA B . n 
B 1 273 SER 273 273 273 SER SER B . n 
B 1 274 LEU 274 274 274 LEU LEU B . n 
B 1 275 ASP 275 275 275 ASP ASP B . n 
B 1 276 PRO 276 276 276 PRO PRO B . n 
B 1 277 ILE 277 277 277 ILE ILE B . n 
B 1 278 ARG 278 278 278 ARG ARG B . n 
B 1 279 ASP 279 279 279 ASP ASP B . n 
B 1 280 SER 280 280 280 SER SER B . n 
B 1 281 GLY 281 281 281 GLY GLY B . n 
B 1 282 ARG 282 282 282 ARG ARG B . n 
B 1 283 ALA 283 283 283 ALA ALA B . n 
B 1 284 TYR 284 284 284 TYR TYR B . n 
B 1 285 ALA 285 285 285 ALA ALA B . n 
B 1 286 LYS 286 286 286 LYS LYS B . n 
B 1 287 ALA 287 287 287 ALA ALA B . n 
B 1 288 LEU 288 288 288 LEU LEU B . n 
B 1 289 ILE 289 289 289 ILE ILE B . n 
B 1 290 ASP 290 290 290 ASP ASP B . n 
B 1 291 ALA 291 291 291 ALA ALA B . n 
B 1 292 GLY 292 292 292 GLY GLY B . n 
B 1 293 ARG 293 293 293 ARG ARG B . n 
B 1 294 ASP 294 294 294 ASP ASP B . n 
B 1 295 CYS 295 295 295 CYS CYS B . n 
B 1 296 VAL 296 296 296 VAL VAL B . n 
B 1 297 PHE 297 297 297 PHE PHE B . n 
B 1 298 LEU 298 298 298 LEU LEU B . n 
B 1 299 GLU 299 299 299 GLU GLU B . n 
B 1 300 MET 300 300 300 MET MET B . n 
B 1 301 ARG 301 301 301 ARG ARG B . n 
B 1 302 GLY 302 302 302 GLY GLY B . n 
B 1 303 VAL 303 303 303 VAL VAL B . n 
B 1 304 THR 304 304 304 THR THR B . n 
B 1 305 HIS 305 305 305 HIS HIS B . n 
B 1 306 SER 306 306 306 SER SER B . n 
B 1 307 PHE 307 307 307 PHE PHE B . n 
B 1 308 THR 308 308 308 THR THR B . n 
B 1 309 ASN 309 309 309 ASN ASN B . n 
B 1 310 LEU 310 310 310 LEU LEU B . n 
B 1 311 ARG 311 311 311 ARG ARG B . n 
B 1 312 GLN 312 312 312 GLN GLN B . n 
B 1 313 MET 313 313 313 MET MET B . n 
B 1 314 VAL 314 314 314 VAL VAL B . n 
B 1 315 PRO 315 315 315 PRO PRO B . n 
B 1 316 SER 316 316 316 SER SER B . n 
B 1 317 THR 317 317 317 THR THR B . n 
B 1 318 GLN 318 318 318 GLN GLN B . n 
B 1 319 ALA 319 319 319 ALA ALA B . n 
B 1 320 ASP 320 320 320 ASP ASP B . n 
B 1 321 LEU 321 321 321 LEU LEU B . n 
B 1 322 GLU 322 322 322 GLU GLU B . n 
B 1 323 ARG 323 323 323 ARG ARG B . n 
B 1 324 VAL 324 324 324 VAL VAL B . n 
B 1 325 ILE 325 325 325 ILE ILE B . n 
B 1 326 ALA 326 326 326 ALA ALA B . n 
B 1 327 ALA 327 327 327 ALA ALA B . n 
B 1 328 MET 328 328 328 MET MET B . n 
B 1 329 GLN 329 329 329 GLN GLN B . n 
B 1 330 PHE 330 330 330 PHE PHE B . n 
B 1 331 MET 331 331 331 MET MET B . n 
B 1 332 LEU 332 332 332 LEU LEU B . n 
B 1 333 ALA 333 333 333 ALA ALA B . n 
B 1 334 ASN 334 334 334 ASN ASN B . n 
B 1 335 PRO 335 335 335 PRO PRO B . n 
B 1 336 ALA 336 336 336 ALA ALA B . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        MES 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   MES 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 MES 1   401 1   MES MES A . 
D 2 MES 1   401 2   MES MES B . 
E 3 HOH 1   501 839 HOH HOH A . 
E 3 HOH 2   502 611 HOH HOH A . 
E 3 HOH 3   503 260 HOH HOH A . 
E 3 HOH 4   504 607 HOH HOH A . 
E 3 HOH 5   505 691 HOH HOH A . 
E 3 HOH 6   506 520 HOH HOH A . 
E 3 HOH 7   507 816 HOH HOH A . 
E 3 HOH 8   508 556 HOH HOH A . 
E 3 HOH 9   509 740 HOH HOH A . 
E 3 HOH 10  510 111 HOH HOH A . 
E 3 HOH 11  511 539 HOH HOH A . 
E 3 HOH 12  512 383 HOH HOH A . 
E 3 HOH 13  513 425 HOH HOH A . 
E 3 HOH 14  514 803 HOH HOH A . 
E 3 HOH 15  515 237 HOH HOH A . 
E 3 HOH 16  516 242 HOH HOH A . 
E 3 HOH 17  517 349 HOH HOH A . 
E 3 HOH 18  518 433 HOH HOH A . 
E 3 HOH 19  519 103 HOH HOH A . 
E 3 HOH 20  520 306 HOH HOH A . 
E 3 HOH 21  521 355 HOH HOH A . 
E 3 HOH 22  522 412 HOH HOH A . 
E 3 HOH 23  523 678 HOH HOH A . 
E 3 HOH 24  524 284 HOH HOH A . 
E 3 HOH 25  525 514 HOH HOH A . 
E 3 HOH 26  526 309 HOH HOH A . 
E 3 HOH 27  527 127 HOH HOH A . 
E 3 HOH 28  528 796 HOH HOH A . 
E 3 HOH 29  529 443 HOH HOH A . 
E 3 HOH 30  530 95  HOH HOH A . 
E 3 HOH 31  531 489 HOH HOH A . 
E 3 HOH 32  532 348 HOH HOH A . 
E 3 HOH 33  533 8   HOH HOH A . 
E 3 HOH 34  534 461 HOH HOH A . 
E 3 HOH 35  535 3   HOH HOH A . 
E 3 HOH 36  536 246 HOH HOH A . 
E 3 HOH 37  537 394 HOH HOH A . 
E 3 HOH 38  538 553 HOH HOH A . 
E 3 HOH 39  539 392 HOH HOH A . 
E 3 HOH 40  540 11  HOH HOH A . 
E 3 HOH 41  541 897 HOH HOH A . 
E 3 HOH 42  542 15  HOH HOH A . 
E 3 HOH 43  543 447 HOH HOH A . 
E 3 HOH 44  544 47  HOH HOH A . 
E 3 HOH 45  545 288 HOH HOH A . 
E 3 HOH 46  546 194 HOH HOH A . 
E 3 HOH 47  547 269 HOH HOH A . 
E 3 HOH 48  548 36  HOH HOH A . 
E 3 HOH 49  549 30  HOH HOH A . 
E 3 HOH 50  550 722 HOH HOH A . 
E 3 HOH 51  551 98  HOH HOH A . 
E 3 HOH 52  552 135 HOH HOH A . 
E 3 HOH 53  553 494 HOH HOH A . 
E 3 HOH 54  554 338 HOH HOH A . 
E 3 HOH 55  555 37  HOH HOH A . 
E 3 HOH 56  556 784 HOH HOH A . 
E 3 HOH 57  557 352 HOH HOH A . 
E 3 HOH 58  558 467 HOH HOH A . 
E 3 HOH 59  559 761 HOH HOH A . 
E 3 HOH 60  560 85  HOH HOH A . 
E 3 HOH 61  561 625 HOH HOH A . 
E 3 HOH 62  562 452 HOH HOH A . 
E 3 HOH 63  563 110 HOH HOH A . 
E 3 HOH 64  564 449 HOH HOH A . 
E 3 HOH 65  565 160 HOH HOH A . 
E 3 HOH 66  566 860 HOH HOH A . 
E 3 HOH 67  567 586 HOH HOH A . 
E 3 HOH 68  568 689 HOH HOH A . 
E 3 HOH 69  569 342 HOH HOH A . 
E 3 HOH 70  570 935 HOH HOH A . 
E 3 HOH 71  571 263 HOH HOH A . 
E 3 HOH 72  572 14  HOH HOH A . 
E 3 HOH 73  573 273 HOH HOH A . 
E 3 HOH 74  574 367 HOH HOH A . 
E 3 HOH 75  575 62  HOH HOH A . 
E 3 HOH 76  576 270 HOH HOH A . 
E 3 HOH 77  577 317 HOH HOH A . 
E 3 HOH 78  578 173 HOH HOH A . 
E 3 HOH 79  579 633 HOH HOH A . 
E 3 HOH 80  580 259 HOH HOH A . 
E 3 HOH 81  581 708 HOH HOH A . 
E 3 HOH 82  582 850 HOH HOH A . 
E 3 HOH 83  583 304 HOH HOH A . 
E 3 HOH 84  584 134 HOH HOH A . 
E 3 HOH 85  585 52  HOH HOH A . 
E 3 HOH 86  586 191 HOH HOH A . 
E 3 HOH 87  587 77  HOH HOH A . 
E 3 HOH 88  588 793 HOH HOH A . 
E 3 HOH 89  589 176 HOH HOH A . 
E 3 HOH 90  590 133 HOH HOH A . 
E 3 HOH 91  591 155 HOH HOH A . 
E 3 HOH 92  592 491 HOH HOH A . 
E 3 HOH 93  593 170 HOH HOH A . 
E 3 HOH 94  594 29  HOH HOH A . 
E 3 HOH 95  595 24  HOH HOH A . 
E 3 HOH 96  596 276 HOH HOH A . 
E 3 HOH 97  597 60  HOH HOH A . 
E 3 HOH 98  598 290 HOH HOH A . 
E 3 HOH 99  599 87  HOH HOH A . 
E 3 HOH 100 600 20  HOH HOH A . 
E 3 HOH 101 601 112 HOH HOH A . 
E 3 HOH 102 602 343 HOH HOH A . 
E 3 HOH 103 603 674 HOH HOH A . 
E 3 HOH 104 604 147 HOH HOH A . 
E 3 HOH 105 605 359 HOH HOH A . 
E 3 HOH 106 606 166 HOH HOH A . 
E 3 HOH 107 607 616 HOH HOH A . 
E 3 HOH 108 608 225 HOH HOH A . 
E 3 HOH 109 609 32  HOH HOH A . 
E 3 HOH 110 610 25  HOH HOH A . 
E 3 HOH 111 611 377 HOH HOH A . 
E 3 HOH 112 612 82  HOH HOH A . 
E 3 HOH 113 613 819 HOH HOH A . 
E 3 HOH 114 614 488 HOH HOH A . 
E 3 HOH 115 615 218 HOH HOH A . 
E 3 HOH 116 616 31  HOH HOH A . 
E 3 HOH 117 617 455 HOH HOH A . 
E 3 HOH 118 618 251 HOH HOH A . 
E 3 HOH 119 619 185 HOH HOH A . 
E 3 HOH 120 620 63  HOH HOH A . 
E 3 HOH 121 621 215 HOH HOH A . 
E 3 HOH 122 622 213 HOH HOH A . 
E 3 HOH 123 623 53  HOH HOH A . 
E 3 HOH 124 624 203 HOH HOH A . 
E 3 HOH 125 625 453 HOH HOH A . 
E 3 HOH 126 626 16  HOH HOH A . 
E 3 HOH 127 627 535 HOH HOH A . 
E 3 HOH 128 628 245 HOH HOH A . 
E 3 HOH 129 629 641 HOH HOH A . 
E 3 HOH 130 630 208 HOH HOH A . 
E 3 HOH 131 631 487 HOH HOH A . 
E 3 HOH 132 632 432 HOH HOH A . 
E 3 HOH 133 633 300 HOH HOH A . 
E 3 HOH 134 634 442 HOH HOH A . 
E 3 HOH 135 635 387 HOH HOH A . 
E 3 HOH 136 636 99  HOH HOH A . 
E 3 HOH 137 637 658 HOH HOH A . 
E 3 HOH 138 638 92  HOH HOH A . 
E 3 HOH 139 639 289 HOH HOH A . 
E 3 HOH 140 640 953 HOH HOH A . 
E 3 HOH 141 641 138 HOH HOH A . 
E 3 HOH 142 642 73  HOH HOH A . 
E 3 HOH 143 643 550 HOH HOH A . 
E 3 HOH 144 644 10  HOH HOH A . 
E 3 HOH 145 645 346 HOH HOH A . 
E 3 HOH 146 646 420 HOH HOH A . 
E 3 HOH 147 647 868 HOH HOH A . 
E 3 HOH 148 648 79  HOH HOH A . 
E 3 HOH 149 649 69  HOH HOH A . 
E 3 HOH 150 650 297 HOH HOH A . 
E 3 HOH 151 651 495 HOH HOH A . 
E 3 HOH 152 652 101 HOH HOH A . 
E 3 HOH 153 653 144 HOH HOH A . 
E 3 HOH 154 654 341 HOH HOH A . 
E 3 HOH 155 655 417 HOH HOH A . 
E 3 HOH 156 656 302 HOH HOH A . 
E 3 HOH 157 657 1   HOH HOH A . 
E 3 HOH 158 658 74  HOH HOH A . 
E 3 HOH 159 659 339 HOH HOH A . 
E 3 HOH 160 660 762 HOH HOH A . 
E 3 HOH 161 661 6   HOH HOH A . 
E 3 HOH 162 662 853 HOH HOH A . 
E 3 HOH 163 663 730 HOH HOH A . 
E 3 HOH 164 664 50  HOH HOH A . 
E 3 HOH 165 665 250 HOH HOH A . 
E 3 HOH 166 666 184 HOH HOH A . 
E 3 HOH 167 667 27  HOH HOH A . 
E 3 HOH 168 668 34  HOH HOH A . 
E 3 HOH 169 669 183 HOH HOH A . 
E 3 HOH 170 670 554 HOH HOH A . 
E 3 HOH 171 671 737 HOH HOH A . 
E 3 HOH 172 672 311 HOH HOH A . 
E 3 HOH 173 673 23  HOH HOH A . 
E 3 HOH 174 674 368 HOH HOH A . 
E 3 HOH 175 675 874 HOH HOH A . 
E 3 HOH 176 676 119 HOH HOH A . 
E 3 HOH 177 677 121 HOH HOH A . 
E 3 HOH 178 678 350 HOH HOH A . 
E 3 HOH 179 679 83  HOH HOH A . 
E 3 HOH 180 680 362 HOH HOH A . 
E 3 HOH 181 681 325 HOH HOH A . 
E 3 HOH 182 682 51  HOH HOH A . 
E 3 HOH 183 683 296 HOH HOH A . 
E 3 HOH 184 684 552 HOH HOH A . 
E 3 HOH 185 685 171 HOH HOH A . 
E 3 HOH 186 686 308 HOH HOH A . 
E 3 HOH 187 687 899 HOH HOH A . 
E 3 HOH 188 688 303 HOH HOH A . 
E 3 HOH 189 689 912 HOH HOH A . 
E 3 HOH 190 690 768 HOH HOH A . 
E 3 HOH 191 691 281 HOH HOH A . 
E 3 HOH 192 692 519 HOH HOH A . 
E 3 HOH 193 693 41  HOH HOH A . 
E 3 HOH 194 694 267 HOH HOH A . 
E 3 HOH 195 695 240 HOH HOH A . 
E 3 HOH 196 696 663 HOH HOH A . 
E 3 HOH 197 697 327 HOH HOH A . 
E 3 HOH 198 698 116 HOH HOH A . 
E 3 HOH 199 699 84  HOH HOH A . 
E 3 HOH 200 700 594 HOH HOH A . 
E 3 HOH 201 701 518 HOH HOH A . 
E 3 HOH 202 702 285 HOH HOH A . 
E 3 HOH 203 703 305 HOH HOH A . 
E 3 HOH 204 704 253 HOH HOH A . 
E 3 HOH 205 705 86  HOH HOH A . 
E 3 HOH 206 706 363 HOH HOH A . 
E 3 HOH 207 707 132 HOH HOH A . 
E 3 HOH 208 708 345 HOH HOH A . 
E 3 HOH 209 709 204 HOH HOH A . 
E 3 HOH 210 710 862 HOH HOH A . 
E 3 HOH 211 711 397 HOH HOH A . 
E 3 HOH 212 712 100 HOH HOH A . 
E 3 HOH 213 713 861 HOH HOH A . 
E 3 HOH 214 714 257 HOH HOH A . 
E 3 HOH 215 715 230 HOH HOH A . 
E 3 HOH 216 716 653 HOH HOH A . 
E 3 HOH 217 717 312 HOH HOH A . 
E 3 HOH 218 718 511 HOH HOH A . 
E 3 HOH 219 719 864 HOH HOH A . 
E 3 HOH 220 720 869 HOH HOH A . 
E 3 HOH 221 721 416 HOH HOH A . 
E 3 HOH 222 722 656 HOH HOH A . 
E 3 HOH 223 723 542 HOH HOH A . 
E 3 HOH 224 724 613 HOH HOH A . 
E 3 HOH 225 725 746 HOH HOH A . 
E 3 HOH 226 726 94  HOH HOH A . 
E 3 HOH 227 727 156 HOH HOH A . 
E 3 HOH 228 728 515 HOH HOH A . 
E 3 HOH 229 729 438 HOH HOH A . 
E 3 HOH 230 730 56  HOH HOH A . 
E 3 HOH 231 731 28  HOH HOH A . 
E 3 HOH 232 732 177 HOH HOH A . 
E 3 HOH 233 733 959 HOH HOH A . 
E 3 HOH 234 734 81  HOH HOH A . 
E 3 HOH 235 735 883 HOH HOH A . 
E 3 HOH 236 736 564 HOH HOH A . 
E 3 HOH 237 737 502 HOH HOH A . 
E 3 HOH 238 738 831 HOH HOH A . 
E 3 HOH 239 739 892 HOH HOH A . 
E 3 HOH 240 740 241 HOH HOH A . 
E 3 HOH 241 741 470 HOH HOH A . 
E 3 HOH 242 742 68  HOH HOH A . 
E 3 HOH 243 743 316 HOH HOH A . 
E 3 HOH 244 744 640 HOH HOH A . 
E 3 HOH 245 745 264 HOH HOH A . 
E 3 HOH 246 746 896 HOH HOH A . 
E 3 HOH 247 747 549 HOH HOH A . 
E 3 HOH 248 748 255 HOH HOH A . 
E 3 HOH 249 749 593 HOH HOH A . 
E 3 HOH 250 750 538 HOH HOH A . 
E 3 HOH 251 751 140 HOH HOH A . 
E 3 HOH 252 752 379 HOH HOH A . 
E 3 HOH 253 753 143 HOH HOH A . 
E 3 HOH 254 754 411 HOH HOH A . 
E 3 HOH 255 755 712 HOH HOH A . 
E 3 HOH 256 756 508 HOH HOH A . 
E 3 HOH 257 757 324 HOH HOH A . 
E 3 HOH 258 758 799 HOH HOH A . 
E 3 HOH 259 759 700 HOH HOH A . 
E 3 HOH 260 760 644 HOH HOH A . 
E 3 HOH 261 761 274 HOH HOH A . 
E 3 HOH 262 762 964 HOH HOH A . 
E 3 HOH 263 763 212 HOH HOH A . 
E 3 HOH 264 764 683 HOH HOH A . 
E 3 HOH 265 765 812 HOH HOH A . 
E 3 HOH 266 766 804 HOH HOH A . 
E 3 HOH 267 767 876 HOH HOH A . 
E 3 HOH 268 768 614 HOH HOH A . 
E 3 HOH 269 769 534 HOH HOH A . 
E 3 HOH 270 770 93  HOH HOH A . 
E 3 HOH 271 771 440 HOH HOH A . 
E 3 HOH 272 772 932 HOH HOH A . 
E 3 HOH 273 773 764 HOH HOH A . 
E 3 HOH 274 774 528 HOH HOH A . 
E 3 HOH 275 775 836 HOH HOH A . 
E 3 HOH 276 776 436 HOH HOH A . 
E 3 HOH 277 777 928 HOH HOH A . 
E 3 HOH 278 778 646 HOH HOH A . 
E 3 HOH 279 779 693 HOH HOH A . 
E 3 HOH 280 780 236 HOH HOH A . 
E 3 HOH 281 781 772 HOH HOH A . 
E 3 HOH 282 782 690 HOH HOH A . 
E 3 HOH 283 783 785 HOH HOH A . 
E 3 HOH 284 784 623 HOH HOH A . 
E 3 HOH 285 785 444 HOH HOH A . 
E 3 HOH 286 786 741 HOH HOH A . 
E 3 HOH 287 787 565 HOH HOH A . 
E 3 HOH 288 788 354 HOH HOH A . 
E 3 HOH 289 789 822 HOH HOH A . 
E 3 HOH 290 790 279 HOH HOH A . 
E 3 HOH 291 791 569 HOH HOH A . 
E 3 HOH 292 792 373 HOH HOH A . 
E 3 HOH 293 793 351 HOH HOH A . 
E 3 HOH 294 794 702 HOH HOH A . 
E 3 HOH 295 795 522 HOH HOH A . 
E 3 HOH 296 796 22  HOH HOH A . 
E 3 HOH 297 797 857 HOH HOH A . 
E 3 HOH 298 798 908 HOH HOH A . 
E 3 HOH 299 799 699 HOH HOH A . 
E 3 HOH 300 800 485 HOH HOH A . 
E 3 HOH 301 801 781 HOH HOH A . 
E 3 HOH 302 802 760 HOH HOH A . 
E 3 HOH 303 803 921 HOH HOH A . 
E 3 HOH 304 804 906 HOH HOH A . 
E 3 HOH 305 805 427 HOH HOH A . 
E 3 HOH 306 806 838 HOH HOH A . 
E 3 HOH 307 807 199 HOH HOH A . 
E 3 HOH 308 808 384 HOH HOH A . 
E 3 HOH 309 809 788 HOH HOH A . 
E 3 HOH 310 810 332 HOH HOH A . 
E 3 HOH 311 811 105 HOH HOH A . 
E 3 HOH 312 812 544 HOH HOH A . 
E 3 HOH 313 813 755 HOH HOH A . 
E 3 HOH 314 814 108 HOH HOH A . 
E 3 HOH 315 815 371 HOH HOH A . 
E 3 HOH 316 816 493 HOH HOH A . 
E 3 HOH 317 817 209 HOH HOH A . 
E 3 HOH 318 818 829 HOH HOH A . 
E 3 HOH 319 819 175 HOH HOH A . 
E 3 HOH 320 820 973 HOH HOH A . 
E 3 HOH 321 821 936 HOH HOH A . 
E 3 HOH 322 822 418 HOH HOH A . 
E 3 HOH 323 823 852 HOH HOH A . 
E 3 HOH 324 824 807 HOH HOH A . 
E 3 HOH 325 825 800 HOH HOH A . 
E 3 HOH 326 826 824 HOH HOH A . 
E 3 HOH 327 827 732 HOH HOH A . 
E 3 HOH 328 828 771 HOH HOH A . 
E 3 HOH 329 829 744 HOH HOH A . 
E 3 HOH 330 830 889 HOH HOH A . 
E 3 HOH 331 831 244 HOH HOH A . 
E 3 HOH 332 832 125 HOH HOH A . 
E 3 HOH 333 833 527 HOH HOH A . 
E 3 HOH 334 834 780 HOH HOH A . 
E 3 HOH 335 835 601 HOH HOH A . 
E 3 HOH 336 836 164 HOH HOH A . 
E 3 HOH 337 837 954 HOH HOH A . 
E 3 HOH 338 838 272 HOH HOH A . 
E 3 HOH 339 839 424 HOH HOH A . 
E 3 HOH 340 840 719 HOH HOH A . 
E 3 HOH 341 841 422 HOH HOH A . 
E 3 HOH 342 842 886 HOH HOH A . 
E 3 HOH 343 843 530 HOH HOH A . 
E 3 HOH 344 844 503 HOH HOH A . 
E 3 HOH 345 845 845 HOH HOH A . 
E 3 HOH 346 846 783 HOH HOH A . 
E 3 HOH 347 847 893 HOH HOH A . 
E 3 HOH 348 848 628 HOH HOH A . 
E 3 HOH 349 849 602 HOH HOH A . 
E 3 HOH 350 850 704 HOH HOH A . 
E 3 HOH 351 851 745 HOH HOH A . 
E 3 HOH 352 852 888 HOH HOH A . 
E 3 HOH 353 853 865 HOH HOH A . 
E 3 HOH 354 854 629 HOH HOH A . 
E 3 HOH 355 855 835 HOH HOH A . 
E 3 HOH 356 856 344 HOH HOH A . 
E 3 HOH 357 857 481 HOH HOH A . 
E 3 HOH 358 858 295 HOH HOH A . 
E 3 HOH 359 859 727 HOH HOH A . 
E 3 HOH 360 860 165 HOH HOH A . 
E 3 HOH 361 861 525 HOH HOH A . 
E 3 HOH 362 862 901 HOH HOH A . 
E 3 HOH 363 863 402 HOH HOH A . 
E 3 HOH 364 864 596 HOH HOH A . 
E 3 HOH 365 865 907 HOH HOH A . 
E 3 HOH 366 866 872 HOH HOH A . 
E 3 HOH 367 867 385 HOH HOH A . 
E 3 HOH 368 868 578 HOH HOH A . 
E 3 HOH 369 869 429 HOH HOH A . 
E 3 HOH 370 870 333 HOH HOH A . 
E 3 HOH 371 871 583 HOH HOH A . 
E 3 HOH 372 872 337 HOH HOH A . 
E 3 HOH 373 873 832 HOH HOH A . 
E 3 HOH 374 874 131 HOH HOH A . 
E 3 HOH 375 875 635 HOH HOH A . 
E 3 HOH 376 876 627 HOH HOH A . 
E 3 HOH 377 877 557 HOH HOH A . 
E 3 HOH 378 878 216 HOH HOH A . 
E 3 HOH 379 879 588 HOH HOH A . 
E 3 HOH 380 880 592 HOH HOH A . 
E 3 HOH 381 881 484 HOH HOH A . 
E 3 HOH 382 882 153 HOH HOH A . 
E 3 HOH 383 883 136 HOH HOH A . 
E 3 HOH 384 884 430 HOH HOH A . 
E 3 HOH 385 885 415 HOH HOH A . 
E 3 HOH 386 886 856 HOH HOH A . 
E 3 HOH 387 887 228 HOH HOH A . 
E 3 HOH 388 888 843 HOH HOH A . 
E 3 HOH 389 889 677 HOH HOH A . 
E 3 HOH 390 890 581 HOH HOH A . 
E 3 HOH 391 891 205 HOH HOH A . 
E 3 HOH 392 892 584 HOH HOH A . 
E 3 HOH 393 893 521 HOH HOH A . 
E 3 HOH 394 894 524 HOH HOH A . 
E 3 HOH 395 895 930 HOH HOH A . 
E 3 HOH 396 896 715 HOH HOH A . 
E 3 HOH 397 897 871 HOH HOH A . 
E 3 HOH 398 898 410 HOH HOH A . 
E 3 HOH 399 899 605 HOH HOH A . 
E 3 HOH 400 900 808 HOH HOH A . 
E 3 HOH 401 901 937 HOH HOH A . 
E 3 HOH 402 902 261 HOH HOH A . 
E 3 HOH 403 903 599 HOH HOH A . 
E 3 HOH 404 904 639 HOH HOH A . 
E 3 HOH 405 905 65  HOH HOH A . 
E 3 HOH 406 906 291 HOH HOH A . 
E 3 HOH 407 907 648 HOH HOH A . 
E 3 HOH 408 908 275 HOH HOH A . 
E 3 HOH 409 909 770 HOH HOH A . 
E 3 HOH 410 910 951 HOH HOH A . 
E 3 HOH 411 911 516 HOH HOH A . 
E 3 HOH 412 912 791 HOH HOH A . 
E 3 HOH 413 913 382 HOH HOH A . 
E 3 HOH 414 914 326 HOH HOH A . 
E 3 HOH 415 915 974 HOH HOH A . 
E 3 HOH 416 916 972 HOH HOH A . 
E 3 HOH 417 917 667 HOH HOH A . 
E 3 HOH 418 918 445 HOH HOH A . 
E 3 HOH 419 919 446 HOH HOH A . 
E 3 HOH 420 920 847 HOH HOH A . 
E 3 HOH 421 921 642 HOH HOH A . 
E 3 HOH 422 922 201 HOH HOH A . 
E 3 HOH 423 923 231 HOH HOH A . 
E 3 HOH 424 924 587 HOH HOH A . 
E 3 HOH 425 925 460 HOH HOH A . 
E 3 HOH 426 926 435 HOH HOH A . 
E 3 HOH 427 927 967 HOH HOH A . 
E 3 HOH 428 928 620 HOH HOH A . 
E 3 HOH 429 929 877 HOH HOH A . 
E 3 HOH 430 930 917 HOH HOH A . 
E 3 HOH 431 931 450 HOH HOH A . 
E 3 HOH 432 932 911 HOH HOH A . 
E 3 HOH 433 933 612 HOH HOH A . 
E 3 HOH 434 934 365 HOH HOH A . 
E 3 HOH 435 935 55  HOH HOH A . 
E 3 HOH 436 936 661 HOH HOH A . 
E 3 HOH 437 937 266 HOH HOH A . 
E 3 HOH 438 938 321 HOH HOH A . 
E 3 HOH 439 939 958 HOH HOH A . 
E 3 HOH 440 940 923 HOH HOH A . 
E 3 HOH 441 941 955 HOH HOH A . 
E 3 HOH 442 942 733 HOH HOH A . 
F 3 HOH 1   501 389 HOH HOH B . 
F 3 HOH 2   502 200 HOH HOH B . 
F 3 HOH 3   503 926 HOH HOH B . 
F 3 HOH 4   504 431 HOH HOH B . 
F 3 HOH 5   505 478 HOH HOH B . 
F 3 HOH 6   506 404 HOH HOH B . 
F 3 HOH 7   507 163 HOH HOH B . 
F 3 HOH 8   508 767 HOH HOH B . 
F 3 HOH 9   509 571 HOH HOH B . 
F 3 HOH 10  510 463 HOH HOH B . 
F 3 HOH 11  511 735 HOH HOH B . 
F 3 HOH 12  512 913 HOH HOH B . 
F 3 HOH 13  513 490 HOH HOH B . 
F 3 HOH 14  514 541 HOH HOH B . 
F 3 HOH 15  515 500 HOH HOH B . 
F 3 HOH 16  516 560 HOH HOH B . 
F 3 HOH 17  517 545 HOH HOH B . 
F 3 HOH 18  518 466 HOH HOH B . 
F 3 HOH 19  519 938 HOH HOH B . 
F 3 HOH 20  520 196 HOH HOH B . 
F 3 HOH 21  521 846 HOH HOH B . 
F 3 HOH 22  522 169 HOH HOH B . 
F 3 HOH 23  523 347 HOH HOH B . 
F 3 HOH 24  524 226 HOH HOH B . 
F 3 HOH 25  525 72  HOH HOH B . 
F 3 HOH 26  526 222 HOH HOH B . 
F 3 HOH 27  527 214 HOH HOH B . 
F 3 HOH 28  528 353 HOH HOH B . 
F 3 HOH 29  529 802 HOH HOH B . 
F 3 HOH 30  530 577 HOH HOH B . 
F 3 HOH 31  531 630 HOH HOH B . 
F 3 HOH 32  532 61  HOH HOH B . 
F 3 HOH 33  533 328 HOH HOH B . 
F 3 HOH 34  534 517 HOH HOH B . 
F 3 HOH 35  535 439 HOH HOH B . 
F 3 HOH 36  536 26  HOH HOH B . 
F 3 HOH 37  537 403 HOH HOH B . 
F 3 HOH 38  538 5   HOH HOH B . 
F 3 HOH 39  539 413 HOH HOH B . 
F 3 HOH 40  540 707 HOH HOH B . 
F 3 HOH 41  541 401 HOH HOH B . 
F 3 HOH 42  542 39  HOH HOH B . 
F 3 HOH 43  543 782 HOH HOH B . 
F 3 HOH 44  544 150 HOH HOH B . 
F 3 HOH 45  545 374 HOH HOH B . 
F 3 HOH 46  546 229 HOH HOH B . 
F 3 HOH 47  547 694 HOH HOH B . 
F 3 HOH 48  548 434 HOH HOH B . 
F 3 HOH 49  549 399 HOH HOH B . 
F 3 HOH 50  550 90  HOH HOH B . 
F 3 HOH 51  551 19  HOH HOH B . 
F 3 HOH 52  552 479 HOH HOH B . 
F 3 HOH 53  553 358 HOH HOH B . 
F 3 HOH 54  554 905 HOH HOH B . 
F 3 HOH 55  555 167 HOH HOH B . 
F 3 HOH 56  556 9   HOH HOH B . 
F 3 HOH 57  557 441 HOH HOH B . 
F 3 HOH 58  558 777 HOH HOH B . 
F 3 HOH 59  559 210 HOH HOH B . 
F 3 HOH 60  560 42  HOH HOH B . 
F 3 HOH 61  561 664 HOH HOH B . 
F 3 HOH 62  562 672 HOH HOH B . 
F 3 HOH 63  563 149 HOH HOH B . 
F 3 HOH 64  564 151 HOH HOH B . 
F 3 HOH 65  565 330 HOH HOH B . 
F 3 HOH 66  566 636 HOH HOH B . 
F 3 HOH 67  567 298 HOH HOH B . 
F 3 HOH 68  568 256 HOH HOH B . 
F 3 HOH 69  569 765 HOH HOH B . 
F 3 HOH 70  570 292 HOH HOH B . 
F 3 HOH 71  571 400 HOH HOH B . 
F 3 HOH 72  572 457 HOH HOH B . 
F 3 HOH 73  573 356 HOH HOH B . 
F 3 HOH 74  574 102 HOH HOH B . 
F 3 HOH 75  575 159 HOH HOH B . 
F 3 HOH 76  576 360 HOH HOH B . 
F 3 HOH 77  577 773 HOH HOH B . 
F 3 HOH 78  578 198 HOH HOH B . 
F 3 HOH 79  579 875 HOH HOH B . 
F 3 HOH 80  580 78  HOH HOH B . 
F 3 HOH 81  581 13  HOH HOH B . 
F 3 HOH 82  582 126 HOH HOH B . 
F 3 HOH 83  583 657 HOH HOH B . 
F 3 HOH 84  584 680 HOH HOH B . 
F 3 HOH 85  585 12  HOH HOH B . 
F 3 HOH 86  586 262 HOH HOH B . 
F 3 HOH 87  587 109 HOH HOH B . 
F 3 HOH 88  588 21  HOH HOH B . 
F 3 HOH 89  589 179 HOH HOH B . 
F 3 HOH 90  590 652 HOH HOH B . 
F 3 HOH 91  591 211 HOH HOH B . 
F 3 HOH 92  592 512 HOH HOH B . 
F 3 HOH 93  593 797 HOH HOH B . 
F 3 HOH 94  594 376 HOH HOH B . 
F 3 HOH 95  595 117 HOH HOH B . 
F 3 HOH 96  596 395 HOH HOH B . 
F 3 HOH 97  597 825 HOH HOH B . 
F 3 HOH 98  598 859 HOH HOH B . 
F 3 HOH 99  599 190 HOH HOH B . 
F 3 HOH 100 600 67  HOH HOH B . 
F 3 HOH 101 601 252 HOH HOH B . 
F 3 HOH 102 602 834 HOH HOH B . 
F 3 HOH 103 603 18  HOH HOH B . 
F 3 HOH 104 604 559 HOH HOH B . 
F 3 HOH 105 605 80  HOH HOH B . 
F 3 HOH 106 606 120 HOH HOH B . 
F 3 HOH 107 607 390 HOH HOH B . 
F 3 HOH 108 608 38  HOH HOH B . 
F 3 HOH 109 609 46  HOH HOH B . 
F 3 HOH 110 610 7   HOH HOH B . 
F 3 HOH 111 611 172 HOH HOH B . 
F 3 HOH 112 612 724 HOH HOH B . 
F 3 HOH 113 613 716 HOH HOH B . 
F 3 HOH 114 614 766 HOH HOH B . 
F 3 HOH 115 615 310 HOH HOH B . 
F 3 HOH 116 616 197 HOH HOH B . 
F 3 HOH 117 617 2   HOH HOH B . 
F 3 HOH 118 618 815 HOH HOH B . 
F 3 HOH 119 619 336 HOH HOH B . 
F 3 HOH 120 620 178 HOH HOH B . 
F 3 HOH 121 621 334 HOH HOH B . 
F 3 HOH 122 622 137 HOH HOH B . 
F 3 HOH 123 623 40  HOH HOH B . 
F 3 HOH 124 624 437 HOH HOH B . 
F 3 HOH 125 625 464 HOH HOH B . 
F 3 HOH 126 626 35  HOH HOH B . 
F 3 HOH 127 627 566 HOH HOH B . 
F 3 HOH 128 628 141 HOH HOH B . 
F 3 HOH 129 629 632 HOH HOH B . 
F 3 HOH 130 630 17  HOH HOH B . 
F 3 HOH 131 631 75  HOH HOH B . 
F 3 HOH 132 632 473 HOH HOH B . 
F 3 HOH 133 633 769 HOH HOH B . 
F 3 HOH 134 634 543 HOH HOH B . 
F 3 HOH 135 635 115 HOH HOH B . 
F 3 HOH 136 636 318 HOH HOH B . 
F 3 HOH 137 637 801 HOH HOH B . 
F 3 HOH 138 638 129 HOH HOH B . 
F 3 HOH 139 639 280 HOH HOH B . 
F 3 HOH 140 640 621 HOH HOH B . 
F 3 HOH 141 641 59  HOH HOH B . 
F 3 HOH 142 642 152 HOH HOH B . 
F 3 HOH 143 643 4   HOH HOH B . 
F 3 HOH 144 644 458 HOH HOH B . 
F 3 HOH 145 645 130 HOH HOH B . 
F 3 HOH 146 646 471 HOH HOH B . 
F 3 HOH 147 647 206 HOH HOH B . 
F 3 HOH 148 648 927 HOH HOH B . 
F 3 HOH 149 649 786 HOH HOH B . 
F 3 HOH 150 650 192 HOH HOH B . 
F 3 HOH 151 651 224 HOH HOH B . 
F 3 HOH 152 652 70  HOH HOH B . 
F 3 HOH 153 653 595 HOH HOH B . 
F 3 HOH 154 654 750 HOH HOH B . 
F 3 HOH 155 655 409 HOH HOH B . 
F 3 HOH 156 656 573 HOH HOH B . 
F 3 HOH 157 657 76  HOH HOH B . 
F 3 HOH 158 658 88  HOH HOH B . 
F 3 HOH 159 659 482 HOH HOH B . 
F 3 HOH 160 660 254 HOH HOH B . 
F 3 HOH 161 661 104 HOH HOH B . 
F 3 HOH 162 662 713 HOH HOH B . 
F 3 HOH 163 663 174 HOH HOH B . 
F 3 HOH 164 664 725 HOH HOH B . 
F 3 HOH 165 665 933 HOH HOH B . 
F 3 HOH 166 666 188 HOH HOH B . 
F 3 HOH 167 667 97  HOH HOH B . 
F 3 HOH 168 668 650 HOH HOH B . 
F 3 HOH 169 669 45  HOH HOH B . 
F 3 HOH 170 670 956 HOH HOH B . 
F 3 HOH 171 671 118 HOH HOH B . 
F 3 HOH 172 672 57  HOH HOH B . 
F 3 HOH 173 673 247 HOH HOH B . 
F 3 HOH 174 674 585 HOH HOH B . 
F 3 HOH 175 675 480 HOH HOH B . 
F 3 HOH 176 676 414 HOH HOH B . 
F 3 HOH 177 677 181 HOH HOH B . 
F 3 HOH 178 678 128 HOH HOH B . 
F 3 HOH 179 679 462 HOH HOH B . 
F 3 HOH 180 680 161 HOH HOH B . 
F 3 HOH 181 681 168 HOH HOH B . 
F 3 HOH 182 682 855 HOH HOH B . 
F 3 HOH 183 683 915 HOH HOH B . 
F 3 HOH 184 684 468 HOH HOH B . 
F 3 HOH 185 685 533 HOH HOH B . 
F 3 HOH 186 686 223 HOH HOH B . 
F 3 HOH 187 687 107 HOH HOH B . 
F 3 HOH 188 688 561 HOH HOH B . 
F 3 HOH 189 689 375 HOH HOH B . 
F 3 HOH 190 690 451 HOH HOH B . 
F 3 HOH 191 691 830 HOH HOH B . 
F 3 HOH 192 692 243 HOH HOH B . 
F 3 HOH 193 693 301 HOH HOH B . 
F 3 HOH 194 694 523 HOH HOH B . 
F 3 HOH 195 695 315 HOH HOH B . 
F 3 HOH 196 696 220 HOH HOH B . 
F 3 HOH 197 697 671 HOH HOH B . 
F 3 HOH 198 698 329 HOH HOH B . 
F 3 HOH 199 699 706 HOH HOH B . 
F 3 HOH 200 700 54  HOH HOH B . 
F 3 HOH 201 701 33  HOH HOH B . 
F 3 HOH 202 702 590 HOH HOH B . 
F 3 HOH 203 703 278 HOH HOH B . 
F 3 HOH 204 704 647 HOH HOH B . 
F 3 HOH 205 705 286 HOH HOH B . 
F 3 HOH 206 706 562 HOH HOH B . 
F 3 HOH 207 707 396 HOH HOH B . 
F 3 HOH 208 708 687 HOH HOH B . 
F 3 HOH 209 709 675 HOH HOH B . 
F 3 HOH 210 710 626 HOH HOH B . 
F 3 HOH 211 711 679 HOH HOH B . 
F 3 HOH 212 712 407 HOH HOH B . 
F 3 HOH 213 713 307 HOH HOH B . 
F 3 HOH 214 714 579 HOH HOH B . 
F 3 HOH 215 715 227 HOH HOH B . 
F 3 HOH 216 716 158 HOH HOH B . 
F 3 HOH 217 717 287 HOH HOH B . 
F 3 HOH 218 718 154 HOH HOH B . 
F 3 HOH 219 719 219 HOH HOH B . 
F 3 HOH 220 720 364 HOH HOH B . 
F 3 HOH 221 721 645 HOH HOH B . 
F 3 HOH 222 722 813 HOH HOH B . 
F 3 HOH 223 723 665 HOH HOH B . 
F 3 HOH 224 724 823 HOH HOH B . 
F 3 HOH 225 725 124 HOH HOH B . 
F 3 HOH 226 726 249 HOH HOH B . 
F 3 HOH 227 727 114 HOH HOH B . 
F 3 HOH 228 728 319 HOH HOH B . 
F 3 HOH 229 729 818 HOH HOH B . 
F 3 HOH 230 730 182 HOH HOH B . 
F 3 HOH 231 731 64  HOH HOH B . 
F 3 HOH 232 732 44  HOH HOH B . 
F 3 HOH 233 733 335 HOH HOH B . 
F 3 HOH 234 734 738 HOH HOH B . 
F 3 HOH 235 735 617 HOH HOH B . 
F 3 HOH 236 736 969 HOH HOH B . 
F 3 HOH 237 737 139 HOH HOH B . 
F 3 HOH 238 738 248 HOH HOH B . 
F 3 HOH 239 739 754 HOH HOH B . 
F 3 HOH 240 740 711 HOH HOH B . 
F 3 HOH 241 741 748 HOH HOH B . 
F 3 HOH 242 742 235 HOH HOH B . 
F 3 HOH 243 743 842 HOH HOH B . 
F 3 HOH 244 744 723 HOH HOH B . 
F 3 HOH 245 745 180 HOH HOH B . 
F 3 HOH 246 746 887 HOH HOH B . 
F 3 HOH 247 747 239 HOH HOH B . 
F 3 HOH 248 748 960 HOH HOH B . 
F 3 HOH 249 749 238 HOH HOH B . 
F 3 HOH 250 750 568 HOH HOH B . 
F 3 HOH 251 751 734 HOH HOH B . 
F 3 HOH 252 752 505 HOH HOH B . 
F 3 HOH 253 753 207 HOH HOH B . 
F 3 HOH 254 754 749 HOH HOH B . 
F 3 HOH 255 755 89  HOH HOH B . 
F 3 HOH 256 756 380 HOH HOH B . 
F 3 HOH 257 757 426 HOH HOH B . 
F 3 HOH 258 758 685 HOH HOH B . 
F 3 HOH 259 759 931 HOH HOH B . 
F 3 HOH 260 760 922 HOH HOH B . 
F 3 HOH 261 761 668 HOH HOH B . 
F 3 HOH 262 762 624 HOH HOH B . 
F 3 HOH 263 763 459 HOH HOH B . 
F 3 HOH 264 764 546 HOH HOH B . 
F 3 HOH 265 765 604 HOH HOH B . 
F 3 HOH 266 766 919 HOH HOH B . 
F 3 HOH 267 767 366 HOH HOH B . 
F 3 HOH 268 768 763 HOH HOH B . 
F 3 HOH 269 769 971 HOH HOH B . 
F 3 HOH 270 770 902 HOH HOH B . 
F 3 HOH 271 771 232 HOH HOH B . 
F 3 HOH 272 772 731 HOH HOH B . 
F 3 HOH 273 773 570 HOH HOH B . 
F 3 HOH 274 774 529 HOH HOH B . 
F 3 HOH 275 775 743 HOH HOH B . 
F 3 HOH 276 776 774 HOH HOH B . 
F 3 HOH 277 777 609 HOH HOH B . 
F 3 HOH 278 778 811 HOH HOH B . 
F 3 HOH 279 779 398 HOH HOH B . 
F 3 HOH 280 780 681 HOH HOH B . 
F 3 HOH 281 781 448 HOH HOH B . 
F 3 HOH 282 782 673 HOH HOH B . 
F 3 HOH 283 783 477 HOH HOH B . 
F 3 HOH 284 784 882 HOH HOH B . 
F 3 HOH 285 785 386 HOH HOH B . 
F 3 HOH 286 786 492 HOH HOH B . 
F 3 HOH 287 787 844 HOH HOH B . 
F 3 HOH 288 788 952 HOH HOH B . 
F 3 HOH 289 789 840 HOH HOH B . 
F 3 HOH 290 790 148 HOH HOH B . 
F 3 HOH 291 791 776 HOH HOH B . 
F 3 HOH 292 792 258 HOH HOH B . 
F 3 HOH 293 793 752 HOH HOH B . 
F 3 HOH 294 794 314 HOH HOH B . 
F 3 HOH 295 795 817 HOH HOH B . 
F 3 HOH 296 796 202 HOH HOH B . 
F 3 HOH 297 797 904 HOH HOH B . 
F 3 HOH 298 798 686 HOH HOH B . 
F 3 HOH 299 799 323 HOH HOH B . 
F 3 HOH 300 800 618 HOH HOH B . 
F 3 HOH 301 801 146 HOH HOH B . 
F 3 HOH 302 802 880 HOH HOH B . 
F 3 HOH 303 803 123 HOH HOH B . 
F 3 HOH 304 804 122 HOH HOH B . 
F 3 HOH 305 805 863 HOH HOH B . 
F 3 HOH 306 806 598 HOH HOH B . 
F 3 HOH 307 807 826 HOH HOH B . 
F 3 HOH 308 808 378 HOH HOH B . 
F 3 HOH 309 809 792 HOH HOH B . 
F 3 HOH 310 810 866 HOH HOH B . 
F 3 HOH 311 811 322 HOH HOH B . 
F 3 HOH 312 812 388 HOH HOH B . 
F 3 HOH 313 813 885 HOH HOH B . 
F 3 HOH 314 814 682 HOH HOH B . 
F 3 HOH 315 815 603 HOH HOH B . 
F 3 HOH 316 816 162 HOH HOH B . 
F 3 HOH 317 817 58  HOH HOH B . 
F 3 HOH 318 818 666 HOH HOH B . 
F 3 HOH 319 819 589 HOH HOH B . 
F 3 HOH 320 820 654 HOH HOH B . 
F 3 HOH 321 821 798 HOH HOH B . 
F 3 HOH 322 822 894 HOH HOH B . 
F 3 HOH 323 823 501 HOH HOH B . 
F 3 HOH 324 824 157 HOH HOH B . 
F 3 HOH 325 825 851 HOH HOH B . 
F 3 HOH 326 826 575 HOH HOH B . 
F 3 HOH 327 827 265 HOH HOH B . 
F 3 HOH 328 828 622 HOH HOH B . 
F 3 HOH 329 829 186 HOH HOH B . 
F 3 HOH 330 830 234 HOH HOH B . 
F 3 HOH 331 831 670 HOH HOH B . 
F 3 HOH 332 832 854 HOH HOH B . 
F 3 HOH 333 833 423 HOH HOH B . 
F 3 HOH 334 834 555 HOH HOH B . 
F 3 HOH 335 835 637 HOH HOH B . 
F 3 HOH 336 836 890 HOH HOH B . 
F 3 HOH 337 837 925 HOH HOH B . 
F 3 HOH 338 838 898 HOH HOH B . 
F 3 HOH 339 839 497 HOH HOH B . 
F 3 HOH 340 840 195 HOH HOH B . 
F 3 HOH 341 841 968 HOH HOH B . 
F 3 HOH 342 842 962 HOH HOH B . 
F 3 HOH 343 843 221 HOH HOH B . 
F 3 HOH 344 844 574 HOH HOH B . 
F 3 HOH 345 845 283 HOH HOH B . 
F 3 HOH 346 846 600 HOH HOH B . 
F 3 HOH 347 847 393 HOH HOH B . 
F 3 HOH 348 848 916 HOH HOH B . 
F 3 HOH 349 849 572 HOH HOH B . 
F 3 HOH 350 850 914 HOH HOH B . 
F 3 HOH 351 851 805 HOH HOH B . 
F 3 HOH 352 852 659 HOH HOH B . 
F 3 HOH 353 853 563 HOH HOH B . 
F 3 HOH 354 854 778 HOH HOH B . 
F 3 HOH 355 855 282 HOH HOH B . 
F 3 HOH 356 856 848 HOH HOH B . 
F 3 HOH 357 857 357 HOH HOH B . 
F 3 HOH 358 858 714 HOH HOH B . 
F 3 HOH 359 859 456 HOH HOH B . 
F 3 HOH 360 860 504 HOH HOH B . 
F 3 HOH 361 861 910 HOH HOH B . 
F 3 HOH 362 862 759 HOH HOH B . 
F 3 HOH 363 863 406 HOH HOH B . 
F 3 HOH 364 864 597 HOH HOH B . 
F 3 HOH 365 865 684 HOH HOH B . 
F 3 HOH 366 866 551 HOH HOH B . 
F 3 HOH 367 867 821 HOH HOH B . 
F 3 HOH 368 868 454 HOH HOH B . 
F 3 HOH 369 869 294 HOH HOH B . 
F 3 HOH 370 870 608 HOH HOH B . 
F 3 HOH 371 871 924 HOH HOH B . 
F 3 HOH 372 872 540 HOH HOH B . 
F 3 HOH 373 873 631 HOH HOH B . 
F 3 HOH 374 874 966 HOH HOH B . 
F 3 HOH 375 875 870 HOH HOH B . 
F 3 HOH 376 876 49  HOH HOH B . 
F 3 HOH 377 877 537 HOH HOH B . 
F 3 HOH 378 878 751 HOH HOH B . 
F 3 HOH 379 879 320 HOH HOH B . 
F 3 HOH 380 880 676 HOH HOH B . 
F 3 HOH 381 881 965 HOH HOH B . 
F 3 HOH 382 882 233 HOH HOH B . 
F 3 HOH 383 883 469 HOH HOH B . 
F 3 HOH 384 884 532 HOH HOH B . 
F 3 HOH 385 885 496 HOH HOH B . 
F 3 HOH 386 886 787 HOH HOH B . 
F 3 HOH 387 887 757 HOH HOH B . 
F 3 HOH 388 888 106 HOH HOH B . 
F 3 HOH 389 889 692 HOH HOH B . 
F 3 HOH 390 890 361 HOH HOH B . 
F 3 HOH 391 891 548 HOH HOH B . 
F 3 HOH 392 892 567 HOH HOH B . 
F 3 HOH 393 893 929 HOH HOH B . 
F 3 HOH 394 894 655 HOH HOH B . 
F 3 HOH 395 895 419 HOH HOH B . 
F 3 HOH 396 896 369 HOH HOH B . 
F 3 HOH 397 897 340 HOH HOH B . 
F 3 HOH 398 898 271 HOH HOH B . 
F 3 HOH 399 899 582 HOH HOH B . 
F 3 HOH 400 900 475 HOH HOH B . 
F 3 HOH 401 901 486 HOH HOH B . 
F 3 HOH 402 902 217 HOH HOH B . 
F 3 HOH 403 903 142 HOH HOH B . 
F 3 HOH 404 904 873 HOH HOH B . 
F 3 HOH 405 905 643 HOH HOH B . 
F 3 HOH 406 906 736 HOH HOH B . 
F 3 HOH 407 907 405 HOH HOH B . 
F 3 HOH 408 908 891 HOH HOH B . 
F 3 HOH 409 909 510 HOH HOH B . 
F 3 HOH 410 910 372 HOH HOH B . 
F 3 HOH 411 911 268 HOH HOH B . 
F 3 HOH 412 912 113 HOH HOH B . 
F 3 HOH 413 913 408 HOH HOH B . 
F 3 HOH 414 914 580 HOH HOH B . 
F 3 HOH 415 915 753 HOH HOH B . 
F 3 HOH 416 916 739 HOH HOH B . 
F 3 HOH 417 917 193 HOH HOH B . 
F 3 HOH 418 918 651 HOH HOH B . 
F 3 HOH 419 919 476 HOH HOH B . 
F 3 HOH 420 920 576 HOH HOH B . 
F 3 HOH 421 921 331 HOH HOH B . 
F 3 HOH 422 922 837 HOH HOH B . 
F 3 HOH 423 923 795 HOH HOH B . 
F 3 HOH 424 924 814 HOH HOH B . 
F 3 HOH 425 925 963 HOH HOH B . 
F 3 HOH 426 926 867 HOH HOH B . 
F 3 HOH 427 927 820 HOH HOH B . 
F 3 HOH 428 928 775 HOH HOH B . 
F 3 HOH 429 929 391 HOH HOH B . 
F 3 HOH 430 930 507 HOH HOH B . 
F 3 HOH 431 931 709 HOH HOH B . 
F 3 HOH 432 932 841 HOH HOH B . 
F 3 HOH 433 933 849 HOH HOH B . 
F 3 HOH 434 934 809 HOH HOH B . 
F 3 HOH 435 935 474 HOH HOH B . 
F 3 HOH 436 936 895 HOH HOH B . 
F 3 HOH 437 937 558 HOH HOH B . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? 1.16_3549 1 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? .         2 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER   ? ? ? .         3 
? 'model building' ? ? ? ? ? ? ? ? ? ? ? Coot     ? ? ? .         4 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? .         5 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9LF7 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     68.657 
_cell.length_a_esd                 ? 
_cell.length_b                     89.603 
_cell.length_b_esd                 ? 
_cell.length_c                     139.592 
_cell.length_c_esd                 ? 
_cell.volume                       858752.280 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9LF7 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            'P 2ac 2ab' 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9LF7 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.00 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          58.98 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          EVAPORATION 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7.5 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.1 M HEPES sodium, 2% v/v polyethylene glycol 400, 2.0 M Ammonium sulfate' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            291.15 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     193.15 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     CCD 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'ADSC QUANTUM 315r' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2018-05-24 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             MAD 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.97891 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'NFPSS BEAMLINE BL19U1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.97891 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL19U1 
_diffrn_source.pdbx_synchrotron_site       NFPSS 
# 
_reflns.B_iso_Wilson_estimate                          11.6 
_reflns.entry_id                                       9LF7 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.8 
_reflns.d_resolution_low                               29.21 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     80299 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.77 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                4.8 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          16.9 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.080 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   1 
_reflns.pdbx_CC_star                                   1 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.8 
_reflns_shell.d_res_low                                     1.864 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             7790 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               1.9 
_reflns_shell.pdbx_chi_squared                              1.102 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  ? 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          98.12 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.01 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               11.6 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9LF7 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.8 
_refine.ls_d_res_low                             29.13 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     80299 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.77 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.1779 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1537 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.8 
_refine_hist.d_res_low                        29.13 
_refine_hist.number_atoms_solvent             879 
_refine_hist.number_atoms_total               5556 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        4653 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         24 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0063  ? 4784 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.9407  ? 6528 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0540  ? 751  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0146  ? 860  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 19.3212 ? 2914 ? f_dihedral_angle_d ? ? 
# 
_refine_ls_shell.R_factor_R_free                  0.2141 
_refine_ls_shell.R_factor_R_free_error            ? 
_refine_ls_shell.R_factor_R_work                  0.1641 
_refine_ls_shell.R_factor_all                     ? 
_refine_ls_shell.R_factor_obs                     ? 
_refine_ls_shell.d_res_high                       1.8 
_refine_ls_shell.d_res_low                        1.864 
_refine_ls_shell.number_reflns_R_free             ? 
_refine_ls_shell.number_reflns_R_work             ? 
_refine_ls_shell.number_reflns_all                ? 
_refine_ls_shell.number_reflns_obs                7790 
_refine_ls_shell.pdbx_R_complete                  ? 
_refine_ls_shell.pdbx_fsc_free                    ? 
_refine_ls_shell.pdbx_fsc_work                    ? 
_refine_ls_shell.pdbx_phase_error                 ? 
_refine_ls_shell.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_ls_shell.pdbx_total_number_of_bins_used   ? 
_refine_ls_shell.percent_reflns_R_free            ? 
_refine_ls_shell.percent_reflns_obs               98.12 
_refine_ls_shell.redundancy_reflns_all            ? 
_refine_ls_shell.redundancy_reflns_obs            ? 
_refine_ls_shell.wR_factor_R_free                 ? 
_refine_ls_shell.wR_factor_R_work                 ? 
_refine_ls_shell.wR_factor_all                    ? 
_refine_ls_shell.wR_factor_obs                    ? 
# 
_struct.entry_id                     9LF7 
_struct.title                        'A PAE-hydrolyse Poc14' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9LF7 
_struct_keywords.text            'Esterase, PAE-hydrolyzing, Hydrolysis, Alpha/beita hydrolyse, HYDROLASE' 
_struct_keywords.pdbx_keywords   HYDROLASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 2 ? 
E N N 3 ? 
F N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    PDB 
_struct_ref.db_code                    9LF7 
_struct_ref.pdbx_db_accession          9LF7 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   ? 
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9LF7 A 1 ? 336 ? 9LF7 1 ? 336 ? 1 336 
2 1 9LF7 B 1 ? 336 ? 9LF7 1 ? 336 ? 1 336 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 3290  ? 
1 MORE         6     ? 
1 'SSA (A^2)'  22250 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ARG A 28  ? ASN A 42  ? ARG A 28  ASN A 42  1 ? 15 
HELX_P HELX_P2  AA2 LYS A 45  ? MET A 49  ? LYS A 45  MET A 49  5 ? 5  
HELX_P HELX_P3  AA3 SER A 50  ? ASP A 66  ? SER A 50  ASP A 66  1 ? 17 
HELX_P HELX_P4  AA4 HIS A 121 ? ASP A 133 ? HIS A 121 ASP A 133 1 ? 13 
HELX_P HELX_P5  AA5 PRO A 150 ? SER A 165 ? PRO A 150 SER A 165 1 ? 16 
HELX_P HELX_P6  AA6 SER A 183 ? SER A 199 ? SER A 183 SER A 199 1 ? 17 
HELX_P HELX_P7  AA7 SER A 221 ? SER A 228 ? SER A 221 SER A 228 1 ? 8  
HELX_P HELX_P8  AA8 THR A 234 ? GLY A 246 ? THR A 234 GLY A 246 1 ? 13 
HELX_P HELX_P9  AA9 PHE A 255 ? GLY A 259 ? PHE A 255 GLY A 259 5 ? 5  
HELX_P HELX_P10 AB1 ILE A 277 ? ALA A 291 ? ILE A 277 ALA A 291 1 ? 15 
HELX_P HELX_P11 AB2 SER A 306 ? LEU A 310 ? SER A 306 LEU A 310 5 ? 5  
HELX_P HELX_P12 AB3 PRO A 315 ? ASN A 334 ? PRO A 315 ASN A 334 1 ? 20 
HELX_P HELX_P13 AB4 ARG B 28  ? VAL B 41  ? ARG B 28  VAL B 41  1 ? 14 
HELX_P HELX_P14 AB5 LYS B 45  ? MET B 49  ? LYS B 45  MET B 49  5 ? 5  
HELX_P HELX_P15 AB6 SER B 50  ? ASP B 66  ? SER B 50  ASP B 66  1 ? 17 
HELX_P HELX_P16 AB7 HIS B 121 ? ASP B 133 ? HIS B 121 ASP B 133 1 ? 13 
HELX_P HELX_P17 AB8 PRO B 150 ? SER B 165 ? PRO B 150 SER B 165 1 ? 16 
HELX_P HELX_P18 AB9 SER B 183 ? SER B 199 ? SER B 183 SER B 199 1 ? 17 
HELX_P HELX_P19 AC1 SER B 221 ? SER B 228 ? SER B 221 SER B 228 1 ? 8  
HELX_P HELX_P20 AC2 THR B 234 ? GLY B 246 ? THR B 234 GLY B 246 1 ? 13 
HELX_P HELX_P21 AC3 PHE B 255 ? GLY B 259 ? PHE B 255 GLY B 259 5 ? 5  
HELX_P HELX_P22 AC4 ILE B 277 ? ALA B 291 ? ILE B 277 ALA B 291 1 ? 15 
HELX_P HELX_P23 AC5 SER B 306 ? LEU B 310 ? SER B 306 LEU B 310 5 ? 5  
HELX_P HELX_P24 AC6 PRO B 315 ? ASN B 334 ? PRO B 315 ASN B 334 1 ? 20 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 ALA 144 A . ? ALA 144 A PRO 145 A ? PRO 145 A 1 -1.09 
2 PHE 149 A . ? PHE 149 A PRO 150 A ? PRO 150 A 1 4.59  
3 ALA 144 B . ? ALA 144 B PRO 145 B ? PRO 145 B 1 2.03  
4 PHE 149 B . ? PHE 149 B PRO 150 B ? PRO 150 B 1 1.82  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 6 ? 
AA2 ? 4 ? 
AA3 ? 6 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA2 1 2 ? parallel      
AA2 2 3 ? anti-parallel 
AA2 3 4 ? parallel      
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? parallel      
AA3 4 5 ? parallel      
AA3 5 6 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 VAL A 74  ? GLY A 82  ? VAL A 74  GLY A 82  
AA1 2 GLY A 85  ? ASP A 93  ? GLY A 85  ASP A 93  
AA1 3 LEU A 136 ? HIS A 140 ? LEU A 136 HIS A 140 
AA1 4 PRO A 101 ? PHE A 108 ? PRO A 101 PHE A 108 
AA1 5 THR A 173 ? ASP A 182 ? THR A 173 ASP A 182 
AA1 6 VAL A 205 ? ILE A 211 ? VAL A 205 ILE A 211 
AA2 1 THR A 267 ? ALA A 272 ? THR A 267 ALA A 272 
AA2 2 CYS A 295 ? MET A 300 ? CYS A 295 MET A 300 
AA2 3 CYS B 295 ? MET B 300 ? CYS B 295 MET B 300 
AA2 4 THR B 267 ? ALA B 272 ? THR B 267 ALA B 272 
AA3 1 VAL B 74  ? GLY B 82  ? VAL B 74  GLY B 82  
AA3 2 GLY B 85  ? ASP B 93  ? GLY B 85  ASP B 93  
AA3 3 LEU B 136 ? HIS B 140 ? LEU B 136 HIS B 140 
AA3 4 PRO B 101 ? PHE B 108 ? PRO B 101 PHE B 108 
AA3 5 THR B 173 ? ASP B 182 ? THR B 173 ASP B 182 
AA3 6 VAL B 205 ? ILE B 211 ? VAL B 205 ILE B 211 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N LEU A 78  ? N LEU A 78  O LEU A 89  ? O LEU A 89  
AA1 2 3 N TYR A 92  ? N TYR A 92  O LEU A 136 ? O LEU A 136 
AA1 3 4 O VAL A 137 ? O VAL A 137 N ILE A 105 ? N ILE A 105 
AA1 4 5 N THR A 106 ? N THR A 106 O ILE A 178 ? O ILE A 178 
AA1 5 6 N GLY A 181 ? N GLY A 181 O ILE A 211 ? O ILE A 211 
AA2 1 2 N THR A 271 ? N THR A 271 O MET A 300 ? O MET A 300 
AA2 2 3 N PHE A 297 ? N PHE A 297 O CYS B 295 ? O CYS B 295 
AA2 3 4 O MET B 300 ? O MET B 300 N THR B 271 ? N THR B 271 
AA3 1 2 N LEU B 78  ? N LEU B 78  O LEU B 89  ? O LEU B 89  
AA3 2 3 N TYR B 92  ? N TYR B 92  O LEU B 136 ? O LEU B 136 
AA3 3 4 O VAL B 137 ? O VAL B 137 N ILE B 105 ? N ILE B 105 
AA3 4 5 N THR B 106 ? N THR B 106 O ILE B 178 ? O ILE B 178 
AA3 5 6 N GLY B 181 ? N GLY B 181 O ILE B 211 ? O ILE B 211 
# 
_pdbx_entry_details.entry_id                   9LF7 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 OG B SER 183 ? ? N4 B MES 401 ? ? 1.31 
2 1 OG B SER 183 ? ? C3 B MES 401 ? ? 2.11 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ARG A 98  ? ? -154.05 81.26   
2  1 ASP A 117 ? ? -166.03 -162.10 
3  1 SER A 183 ? ? 67.44   -117.75 
4  1 PHE A 212 ? ? 24.57   63.03   
5  1 LEU A 232 ? ? 77.86   -63.60  
6  1 ASP B 117 ? ? -167.82 -160.83 
7  1 PHE B 149 ? ? -38.68  134.13  
8  1 SER B 183 ? ? 64.39   -119.15 
9  1 PHE B 212 ? ? 25.35   62.32   
10 1 LEU B 232 ? ? 75.21   -69.86  
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1 1 ARG A 301 ? ? 0.126 'SIDE CHAIN' 
2 1 ARG A 311 ? ? 0.261 'SIDE CHAIN' 
3 1 ARG B 311 ? ? 0.258 'SIDE CHAIN' 
# 
loop_
_pdbx_distant_solvent_atoms.id 
_pdbx_distant_solvent_atoms.PDB_model_num 
_pdbx_distant_solvent_atoms.auth_atom_id 
_pdbx_distant_solvent_atoms.label_alt_id 
_pdbx_distant_solvent_atoms.auth_asym_id 
_pdbx_distant_solvent_atoms.auth_comp_id 
_pdbx_distant_solvent_atoms.auth_seq_id 
_pdbx_distant_solvent_atoms.PDB_ins_code 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance 
1  1 O ? A HOH 936 ? 5.87 . 
2  1 O ? A HOH 937 ? 6.06 . 
3  1 O ? A HOH 938 ? 6.10 . 
4  1 O ? A HOH 939 ? 6.34 . 
5  1 O ? A HOH 940 ? 6.51 . 
6  1 O ? A HOH 941 ? 6.75 . 
7  1 O ? A HOH 942 ? 6.79 . 
8  1 O ? B HOH 934 ? 5.84 . 
9  1 O ? B HOH 935 ? 6.12 . 
10 1 O ? B HOH 936 ? 6.33 . 
11 1 O ? B HOH 937 ? 6.89 . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 1  ? A MET 1  
2  1 Y 1 A ARG 2  ? A ARG 2  
3  1 Y 1 A LEU 3  ? A LEU 3  
4  1 Y 1 A ALA 4  ? A ALA 4  
5  1 Y 1 A LYS 5  ? A LYS 5  
6  1 Y 1 A LEU 6  ? A LEU 6  
7  1 Y 1 A PRO 7  ? A PRO 7  
8  1 Y 1 A ALA 8  ? A ALA 8  
9  1 Y 1 A LEU 9  ? A LEU 9  
10 1 Y 1 A ALA 10 ? A ALA 10 
11 1 Y 1 A TYR 11 ? A TYR 11 
12 1 Y 1 A ARG 12 ? A ARG 12 
13 1 Y 1 A SER 13 ? A SER 13 
14 1 Y 1 A ALA 14 ? A ALA 14 
15 1 Y 1 A LYS 15 ? A LYS 15 
16 1 Y 1 A ASP 16 ? A ASP 16 
17 1 Y 1 A THR 17 ? A THR 17 
18 1 Y 1 A GLY 18 ? A GLY 18 
19 1 Y 1 A GLU 19 ? A GLU 19 
20 1 Y 1 A SER 20 ? A SER 20 
21 1 Y 1 A MET 21 ? A MET 21 
22 1 Y 1 A THR 22 ? A THR 22 
23 1 Y 1 A ASP 23 ? A ASP 23 
24 1 Y 1 B MET 1  ? B MET 1  
25 1 Y 1 B ARG 2  ? B ARG 2  
26 1 Y 1 B LEU 3  ? B LEU 3  
27 1 Y 1 B ALA 4  ? B ALA 4  
28 1 Y 1 B LYS 5  ? B LYS 5  
29 1 Y 1 B LEU 6  ? B LEU 6  
30 1 Y 1 B PRO 7  ? B PRO 7  
31 1 Y 1 B ALA 8  ? B ALA 8  
32 1 Y 1 B LEU 9  ? B LEU 9  
33 1 Y 1 B ALA 10 ? B ALA 10 
34 1 Y 1 B TYR 11 ? B TYR 11 
35 1 Y 1 B ARG 12 ? B ARG 12 
36 1 Y 1 B SER 13 ? B SER 13 
37 1 Y 1 B ALA 14 ? B ALA 14 
38 1 Y 1 B LYS 15 ? B LYS 15 
39 1 Y 1 B ASP 16 ? B ASP 16 
40 1 Y 1 B THR 17 ? B THR 17 
41 1 Y 1 B GLY 18 ? B GLY 18 
42 1 Y 1 B GLU 19 ? B GLU 19 
43 1 Y 1 B SER 20 ? B SER 20 
44 1 Y 1 B MET 21 ? B MET 21 
45 1 Y 1 B THR 22 ? B THR 22 
46 1 Y 1 B ASP 23 ? B ASP 23 
47 1 Y 1 B ALA 99 ? B ALA 99 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
HOH O    O N N 158 
HOH H1   H N N 159 
HOH H2   H N N 160 
ILE N    N N N 161 
ILE CA   C N S 162 
ILE C    C N N 163 
ILE O    O N N 164 
ILE CB   C N S 165 
ILE CG1  C N N 166 
ILE CG2  C N N 167 
ILE CD1  C N N 168 
ILE OXT  O N N 169 
ILE H    H N N 170 
ILE H2   H N N 171 
ILE HA   H N N 172 
ILE HB   H N N 173 
ILE HG12 H N N 174 
ILE HG13 H N N 175 
ILE HG21 H N N 176 
ILE HG22 H N N 177 
ILE HG23 H N N 178 
ILE HD11 H N N 179 
ILE HD12 H N N 180 
ILE HD13 H N N 181 
ILE HXT  H N N 182 
LEU N    N N N 183 
LEU CA   C N S 184 
LEU C    C N N 185 
LEU O    O N N 186 
LEU CB   C N N 187 
LEU CG   C N N 188 
LEU CD1  C N N 189 
LEU CD2  C N N 190 
LEU OXT  O N N 191 
LEU H    H N N 192 
LEU H2   H N N 193 
LEU HA   H N N 194 
LEU HB2  H N N 195 
LEU HB3  H N N 196 
LEU HG   H N N 197 
LEU HD11 H N N 198 
LEU HD12 H N N 199 
LEU HD13 H N N 200 
LEU HD21 H N N 201 
LEU HD22 H N N 202 
LEU HD23 H N N 203 
LEU HXT  H N N 204 
LYS N    N N N 205 
LYS CA   C N S 206 
LYS C    C N N 207 
LYS O    O N N 208 
LYS CB   C N N 209 
LYS CG   C N N 210 
LYS CD   C N N 211 
LYS CE   C N N 212 
LYS NZ   N N N 213 
LYS OXT  O N N 214 
LYS H    H N N 215 
LYS H2   H N N 216 
LYS HA   H N N 217 
LYS HB2  H N N 218 
LYS HB3  H N N 219 
LYS HG2  H N N 220 
LYS HG3  H N N 221 
LYS HD2  H N N 222 
LYS HD3  H N N 223 
LYS HE2  H N N 224 
LYS HE3  H N N 225 
LYS HZ1  H N N 226 
LYS HZ2  H N N 227 
LYS HZ3  H N N 228 
LYS HXT  H N N 229 
MES O1   O N N 230 
MES C2   C N N 231 
MES C3   C N N 232 
MES N4   N N N 233 
MES C5   C N N 234 
MES C6   C N N 235 
MES C7   C N N 236 
MES C8   C N N 237 
MES S    S N N 238 
MES O1S  O N N 239 
MES O2S  O N N 240 
MES O3S  O N N 241 
MES H21  H N N 242 
MES H22  H N N 243 
MES H31  H N N 244 
MES H32  H N N 245 
MES HN4  H N N 246 
MES H51  H N N 247 
MES H52  H N N 248 
MES H61  H N N 249 
MES H62  H N N 250 
MES H71  H N N 251 
MES H72  H N N 252 
MES H81  H N N 253 
MES H82  H N N 254 
MET N    N N N 255 
MET CA   C N S 256 
MET C    C N N 257 
MET O    O N N 258 
MET CB   C N N 259 
MET CG   C N N 260 
MET SD   S N N 261 
MET CE   C N N 262 
MET OXT  O N N 263 
MET H    H N N 264 
MET H2   H N N 265 
MET HA   H N N 266 
MET HB2  H N N 267 
MET HB3  H N N 268 
MET HG2  H N N 269 
MET HG3  H N N 270 
MET HE1  H N N 271 
MET HE2  H N N 272 
MET HE3  H N N 273 
MET HXT  H N N 274 
PHE N    N N N 275 
PHE CA   C N S 276 
PHE C    C N N 277 
PHE O    O N N 278 
PHE CB   C N N 279 
PHE CG   C Y N 280 
PHE CD1  C Y N 281 
PHE CD2  C Y N 282 
PHE CE1  C Y N 283 
PHE CE2  C Y N 284 
PHE CZ   C Y N 285 
PHE OXT  O N N 286 
PHE H    H N N 287 
PHE H2   H N N 288 
PHE HA   H N N 289 
PHE HB2  H N N 290 
PHE HB3  H N N 291 
PHE HD1  H N N 292 
PHE HD2  H N N 293 
PHE HE1  H N N 294 
PHE HE2  H N N 295 
PHE HZ   H N N 296 
PHE HXT  H N N 297 
PRO N    N N N 298 
PRO CA   C N S 299 
PRO C    C N N 300 
PRO O    O N N 301 
PRO CB   C N N 302 
PRO CG   C N N 303 
PRO CD   C N N 304 
PRO OXT  O N N 305 
PRO H    H N N 306 
PRO HA   H N N 307 
PRO HB2  H N N 308 
PRO HB3  H N N 309 
PRO HG2  H N N 310 
PRO HG3  H N N 311 
PRO HD2  H N N 312 
PRO HD3  H N N 313 
PRO HXT  H N N 314 
SER N    N N N 315 
SER CA   C N S 316 
SER C    C N N 317 
SER O    O N N 318 
SER CB   C N N 319 
SER OG   O N N 320 
SER OXT  O N N 321 
SER H    H N N 322 
SER H2   H N N 323 
SER HA   H N N 324 
SER HB2  H N N 325 
SER HB3  H N N 326 
SER HG   H N N 327 
SER HXT  H N N 328 
THR N    N N N 329 
THR CA   C N S 330 
THR C    C N N 331 
THR O    O N N 332 
THR CB   C N R 333 
THR OG1  O N N 334 
THR CG2  C N N 335 
THR OXT  O N N 336 
THR H    H N N 337 
THR H2   H N N 338 
THR HA   H N N 339 
THR HB   H N N 340 
THR HG1  H N N 341 
THR HG21 H N N 342 
THR HG22 H N N 343 
THR HG23 H N N 344 
THR HXT  H N N 345 
TRP N    N N N 346 
TRP CA   C N S 347 
TRP C    C N N 348 
TRP O    O N N 349 
TRP CB   C N N 350 
TRP CG   C Y N 351 
TRP CD1  C Y N 352 
TRP CD2  C Y N 353 
TRP NE1  N Y N 354 
TRP CE2  C Y N 355 
TRP CE3  C Y N 356 
TRP CZ2  C Y N 357 
TRP CZ3  C Y N 358 
TRP CH2  C Y N 359 
TRP OXT  O N N 360 
TRP H    H N N 361 
TRP H2   H N N 362 
TRP HA   H N N 363 
TRP HB2  H N N 364 
TRP HB3  H N N 365 
TRP HD1  H N N 366 
TRP HE1  H N N 367 
TRP HE3  H N N 368 
TRP HZ2  H N N 369 
TRP HZ3  H N N 370 
TRP HH2  H N N 371 
TRP HXT  H N N 372 
TYR N    N N N 373 
TYR CA   C N S 374 
TYR C    C N N 375 
TYR O    O N N 376 
TYR CB   C N N 377 
TYR CG   C Y N 378 
TYR CD1  C Y N 379 
TYR CD2  C Y N 380 
TYR CE1  C Y N 381 
TYR CE2  C Y N 382 
TYR CZ   C Y N 383 
TYR OH   O N N 384 
TYR OXT  O N N 385 
TYR H    H N N 386 
TYR H2   H N N 387 
TYR HA   H N N 388 
TYR HB2  H N N 389 
TYR HB3  H N N 390 
TYR HD1  H N N 391 
TYR HD2  H N N 392 
TYR HE1  H N N 393 
TYR HE2  H N N 394 
TYR HH   H N N 395 
TYR HXT  H N N 396 
VAL N    N N N 397 
VAL CA   C N S 398 
VAL C    C N N 399 
VAL O    O N N 400 
VAL CB   C N N 401 
VAL CG1  C N N 402 
VAL CG2  C N N 403 
VAL OXT  O N N 404 
VAL H    H N N 405 
VAL H2   H N N 406 
VAL HA   H N N 407 
VAL HB   H N N 408 
VAL HG11 H N N 409 
VAL HG12 H N N 410 
VAL HG13 H N N 411 
VAL HG21 H N N 412 
VAL HG22 H N N 413 
VAL HG23 H N N 414 
VAL HXT  H N N 415 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MES O1  C2   sing N N 218 
MES O1  C6   sing N N 219 
MES C2  C3   sing N N 220 
MES C2  H21  sing N N 221 
MES C2  H22  sing N N 222 
MES C3  N4   sing N N 223 
MES C3  H31  sing N N 224 
MES C3  H32  sing N N 225 
MES N4  C5   sing N N 226 
MES N4  C7   sing N N 227 
MES N4  HN4  sing N N 228 
MES C5  C6   sing N N 229 
MES C5  H51  sing N N 230 
MES C5  H52  sing N N 231 
MES C6  H61  sing N N 232 
MES C6  H62  sing N N 233 
MES C7  C8   sing N N 234 
MES C7  H71  sing N N 235 
MES C7  H72  sing N N 236 
MES C8  S    sing N N 237 
MES C8  H81  sing N N 238 
MES C8  H82  sing N N 239 
MES S   O1S  doub N N 240 
MES S   O2S  doub N N 241 
MES S   O3S  sing N N 242 
MET N   CA   sing N N 243 
MET N   H    sing N N 244 
MET N   H2   sing N N 245 
MET CA  C    sing N N 246 
MET CA  CB   sing N N 247 
MET CA  HA   sing N N 248 
MET C   O    doub N N 249 
MET C   OXT  sing N N 250 
MET CB  CG   sing N N 251 
MET CB  HB2  sing N N 252 
MET CB  HB3  sing N N 253 
MET CG  SD   sing N N 254 
MET CG  HG2  sing N N 255 
MET CG  HG3  sing N N 256 
MET SD  CE   sing N N 257 
MET CE  HE1  sing N N 258 
MET CE  HE2  sing N N 259 
MET CE  HE3  sing N N 260 
MET OXT HXT  sing N N 261 
PHE N   CA   sing N N 262 
PHE N   H    sing N N 263 
PHE N   H2   sing N N 264 
PHE CA  C    sing N N 265 
PHE CA  CB   sing N N 266 
PHE CA  HA   sing N N 267 
PHE C   O    doub N N 268 
PHE C   OXT  sing N N 269 
PHE CB  CG   sing N N 270 
PHE CB  HB2  sing N N 271 
PHE CB  HB3  sing N N 272 
PHE CG  CD1  doub Y N 273 
PHE CG  CD2  sing Y N 274 
PHE CD1 CE1  sing Y N 275 
PHE CD1 HD1  sing N N 276 
PHE CD2 CE2  doub Y N 277 
PHE CD2 HD2  sing N N 278 
PHE CE1 CZ   doub Y N 279 
PHE CE1 HE1  sing N N 280 
PHE CE2 CZ   sing Y N 281 
PHE CE2 HE2  sing N N 282 
PHE CZ  HZ   sing N N 283 
PHE OXT HXT  sing N N 284 
PRO N   CA   sing N N 285 
PRO N   CD   sing N N 286 
PRO N   H    sing N N 287 
PRO CA  C    sing N N 288 
PRO CA  CB   sing N N 289 
PRO CA  HA   sing N N 290 
PRO C   O    doub N N 291 
PRO C   OXT  sing N N 292 
PRO CB  CG   sing N N 293 
PRO CB  HB2  sing N N 294 
PRO CB  HB3  sing N N 295 
PRO CG  CD   sing N N 296 
PRO CG  HG2  sing N N 297 
PRO CG  HG3  sing N N 298 
PRO CD  HD2  sing N N 299 
PRO CD  HD3  sing N N 300 
PRO OXT HXT  sing N N 301 
SER N   CA   sing N N 302 
SER N   H    sing N N 303 
SER N   H2   sing N N 304 
SER CA  C    sing N N 305 
SER CA  CB   sing N N 306 
SER CA  HA   sing N N 307 
SER C   O    doub N N 308 
SER C   OXT  sing N N 309 
SER CB  OG   sing N N 310 
SER CB  HB2  sing N N 311 
SER CB  HB3  sing N N 312 
SER OG  HG   sing N N 313 
SER OXT HXT  sing N N 314 
THR N   CA   sing N N 315 
THR N   H    sing N N 316 
THR N   H2   sing N N 317 
THR CA  C    sing N N 318 
THR CA  CB   sing N N 319 
THR CA  HA   sing N N 320 
THR C   O    doub N N 321 
THR C   OXT  sing N N 322 
THR CB  OG1  sing N N 323 
THR CB  CG2  sing N N 324 
THR CB  HB   sing N N 325 
THR OG1 HG1  sing N N 326 
THR CG2 HG21 sing N N 327 
THR CG2 HG22 sing N N 328 
THR CG2 HG23 sing N N 329 
THR OXT HXT  sing N N 330 
TRP N   CA   sing N N 331 
TRP N   H    sing N N 332 
TRP N   H2   sing N N 333 
TRP CA  C    sing N N 334 
TRP CA  CB   sing N N 335 
TRP CA  HA   sing N N 336 
TRP C   O    doub N N 337 
TRP C   OXT  sing N N 338 
TRP CB  CG   sing N N 339 
TRP CB  HB2  sing N N 340 
TRP CB  HB3  sing N N 341 
TRP CG  CD1  doub Y N 342 
TRP CG  CD2  sing Y N 343 
TRP CD1 NE1  sing Y N 344 
TRP CD1 HD1  sing N N 345 
TRP CD2 CE2  doub Y N 346 
TRP CD2 CE3  sing Y N 347 
TRP NE1 CE2  sing Y N 348 
TRP NE1 HE1  sing N N 349 
TRP CE2 CZ2  sing Y N 350 
TRP CE3 CZ3  doub Y N 351 
TRP CE3 HE3  sing N N 352 
TRP CZ2 CH2  doub Y N 353 
TRP CZ2 HZ2  sing N N 354 
TRP CZ3 CH2  sing Y N 355 
TRP CZ3 HZ3  sing N N 356 
TRP CH2 HH2  sing N N 357 
TRP OXT HXT  sing N N 358 
TYR N   CA   sing N N 359 
TYR N   H    sing N N 360 
TYR N   H2   sing N N 361 
TYR CA  C    sing N N 362 
TYR CA  CB   sing N N 363 
TYR CA  HA   sing N N 364 
TYR C   O    doub N N 365 
TYR C   OXT  sing N N 366 
TYR CB  CG   sing N N 367 
TYR CB  HB2  sing N N 368 
TYR CB  HB3  sing N N 369 
TYR CG  CD1  doub Y N 370 
TYR CG  CD2  sing Y N 371 
TYR CD1 CE1  sing Y N 372 
TYR CD1 HD1  sing N N 373 
TYR CD2 CE2  doub Y N 374 
TYR CD2 HD2  sing N N 375 
TYR CE1 CZ   doub Y N 376 
TYR CE1 HE1  sing N N 377 
TYR CE2 CZ   sing Y N 378 
TYR CE2 HE2  sing N N 379 
TYR CZ  OH   sing N N 380 
TYR OH  HH   sing N N 381 
TYR OXT HXT  sing N N 382 
VAL N   CA   sing N N 383 
VAL N   H    sing N N 384 
VAL N   H2   sing N N 385 
VAL CA  C    sing N N 386 
VAL CA  CB   sing N N 387 
VAL CA  HA   sing N N 388 
VAL C   O    doub N N 389 
VAL C   OXT  sing N N 390 
VAL CB  CG1  sing N N 391 
VAL CB  CG2  sing N N 392 
VAL CB  HB   sing N N 393 
VAL CG1 HG11 sing N N 394 
VAL CG1 HG12 sing N N 395 
VAL CG1 HG13 sing N N 396 
VAL CG2 HG21 sing N N 397 
VAL CG2 HG22 sing N N 398 
VAL CG2 HG23 sing N N 399 
VAL OXT HXT  sing N N 400 
# 
_pdbx_audit_support.funding_organization   'Other government' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6kf5 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9LF7 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.014565 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.011160 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.007164 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
H 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . THR A 1 24  ? 29.74400 -16.23800 141.27700 1.000 32.72000 ? 24  THR A N   1 
ATOM   2    C CA  . THR A 1 24  ? 28.82500 -15.21000 140.79500 1.000 27.22000 ? 24  THR A CA  1 
ATOM   3    C C   . THR A 1 24  ? 28.05900 -14.57400 141.94500 1.000 24.23000 ? 24  THR A C   1 
ATOM   4    O O   . THR A 1 24  ? 27.29500 -15.24900 142.63800 1.000 25.68000 ? 24  THR A O   1 
ATOM   5    C CB  . THR A 1 24  ? 27.81700 -15.78000 139.78200 1.000 32.41000 ? 24  THR A CB  1 
ATOM   6    O OG1 . THR A 1 24  ? 28.52200 -16.48100 138.75100 1.000 38.20000 ? 24  THR A OG1 1 
ATOM   7    C CG2 . THR A 1 24  ? 26.99300 -14.65700 139.15800 1.000 29.97000 ? 24  THR A CG2 1 
ATOM   8    N N   . PRO A 1 25  ? 28.26300 -13.27500 142.15400 1.000 20.17000 ? 25  PRO A N   1 
ATOM   9    C CA  . PRO A 1 25  ? 27.56000 -12.59000 143.24500 1.000 17.67000 ? 25  PRO A CA  1 
ATOM   10   C C   . PRO A 1 25  ? 26.05800 -12.61500 143.01300 1.000 15.66000 ? 25  PRO A C   1 
ATOM   11   O O   . PRO A 1 25  ? 25.57900 -12.55100 141.87600 1.000 16.10000 ? 25  PRO A O   1 
ATOM   12   C CB  . PRO A 1 25  ? 28.11000 -11.15700 143.18700 1.000 18.98000 ? 25  PRO A CB  1 
ATOM   13   C CG  . PRO A 1 25  ? 29.36600 -11.24600 142.36500 1.000 23.55000 ? 25  PRO A CG  1 
ATOM   14   C CD  . PRO A 1 25  ? 29.14700 -12.37000 141.40200 1.000 20.24000 ? 25  PRO A CD  1 
ATOM   15   N N   . TYR A 1 26  ? 25.31000 -12.71800 144.10800 1.000 11.11000 ? 26  TYR A N   1 
ATOM   16   C CA  . TYR A 1 26  ? 23.85800 -12.76400 144.00100 1.000 12.11000 ? 26  TYR A CA  1 
ATOM   17   C C   . TYR A 1 26  ? 23.32700 -11.48600 143.36000 1.000 11.96000 ? 26  TYR A C   1 
ATOM   18   O O   . TYR A 1 26  ? 23.69000 -10.38300 143.77100 1.000 9.74000  ? 26  TYR A O   1 
ATOM   19   C CB  . TYR A 1 26  ? 23.24500 -12.94600 145.38300 1.000 11.89000 ? 26  TYR A CB  1 
ATOM   20   C CG  . TYR A 1 26  ? 21.75800 -12.69200 145.41700 1.000 13.56000 ? 26  TYR A CG  1 
ATOM   21   C CD1 . TYR A 1 26  ? 20.86700 -13.57600 144.82900 1.000 14.51000 ? 26  TYR A CD1 1 
ATOM   22   C CD2 . TYR A 1 26  ? 21.24700 -11.55300 146.03300 1.000 11.91000 ? 26  TYR A CD2 1 
ATOM   23   C CE1 . TYR A 1 26  ? 19.49500 -13.34000 144.85800 1.000 19.02000 ? 26  TYR A CE1 1 
ATOM   24   C CE2 . TYR A 1 26  ? 19.88200 -11.30500 146.06200 1.000 12.24000 ? 26  TYR A CE2 1 
ATOM   25   C CZ  . TYR A 1 26  ? 19.01300 -12.20500 145.48500 1.000 18.07000 ? 26  TYR A CZ  1 
ATOM   26   O OH  . TYR A 1 26  ? 17.66100 -11.95000 145.53200 1.000 19.95000 ? 26  TYR A OH  1 
ATOM   27   N N   . ILE A 1 27  ? 22.45500 -11.63300 142.35900 1.000 10.40000 ? 27  ILE A N   1 
ATOM   28   C CA  . ILE A 1 27  ? 21.82900 -10.48700 141.69700 1.000 10.30000 ? 27  ILE A CA  1 
ATOM   29   C C   . ILE A 1 27  ? 20.36000 -10.80800 141.43800 1.000 10.25000 ? 27  ILE A C   1 
ATOM   30   O O   . ILE A 1 27  ? 20.01800 -11.92000 141.02100 1.000 12.02000 ? 27  ILE A O   1 
ATOM   31   C CB  . ILE A 1 27  ? 22.56900 -10.11100 140.39200 1.000 9.53000  ? 27  ILE A CB  1 
ATOM   32   C CG1 . ILE A 1 27  ? 21.90900 -8.90500  139.70600 1.000 8.64000  ? 27  ILE A CG1 1 
ATOM   33   C CG2 . ILE A 1 27  ? 22.67000 -11.31600 139.44400 1.000 13.59000 ? 27  ILE A CG2 1 
ATOM   34   C CD1 . ILE A 1 27  ? 22.77600 -8.29000  138.62700 1.000 11.65000 ? 27  ILE A CD1 1 
ATOM   35   N N   . ARG A 1 28  ? 19.48500 -9.83400  141.70000 1.000 8.12000  ? 28  ARG A N   1 
ATOM   36   C CA  . ARG A 1 28  ? 18.06400 -10.01400 141.43900 1.000 7.98000  ? 28  ARG A CA  1 
ATOM   37   C C   . ARG A 1 28  ? 17.79100 -10.11100 139.93700 1.000 8.52000  ? 28  ARG A C   1 
ATOM   38   O O   . ARG A 1 28  ? 18.47200 -9.47600  139.13100 1.000 9.74000  ? 28  ARG A O   1 
ATOM   39   C CB  . ARG A 1 28  ? 17.26200 -8.85300  142.00900 1.000 7.41000  ? 28  ARG A CB  1 
ATOM   40   C CG  . ARG A 1 28  ? 17.29000 -8.78400  143.51500 1.000 7.74000  ? 28  ARG A CG  1 
ATOM   41   C CD  . ARG A 1 28  ? 16.49000 -7.58800  143.99500 1.000 9.75000  ? 28  ARG A CD  1 
ATOM   42   N NE  . ARG A 1 28  ? 16.86000 -7.24900  145.36200 1.000 8.55000  ? 28  ARG A NE  1 
ATOM   43   C CZ  . ARG A 1 28  ? 16.48100 -6.13900  145.99000 1.000 11.56000 ? 28  ARG A CZ  1 
ATOM   44   N NH1 . ARG A 1 28  ? 15.69900 -5.24500  145.38100 1.000 8.01000  ? 28  ARG A NH1 1 
ATOM   45   N NH2 . ARG A 1 28  ? 16.90000 -5.92200  147.23100 1.000 11.45000 ? 28  ARG A NH2 1 
ATOM   46   N N   . PRO A 1 29  ? 16.78800 -10.89900 139.53600 1.000 10.06000 ? 29  PRO A N   1 
ATOM   47   C CA  . PRO A 1 29  ? 16.44500 -10.97200 138.10100 1.000 13.56000 ? 29  PRO A CA  1 
ATOM   48   C C   . PRO A 1 29  ? 16.15700 -9.62300  137.45600 1.000 13.10000 ? 29  PRO A C   1 
ATOM   49   O O   . PRO A 1 29  ? 16.58900 -9.39700  136.31600 1.000 10.94000 ? 29  PRO A O   1 
ATOM   50   C CB  . PRO A 1 29  ? 15.20800 -11.88000 138.09300 1.000 14.82000 ? 29  PRO A CB  1 
ATOM   51   C CG  . PRO A 1 29  ? 15.42600 -12.79600 139.27600 1.000 17.34000 ? 29  PRO A CG  1 
ATOM   52   C CD  . PRO A 1 29  ? 16.08000 -11.92000 140.33200 1.000 15.15000 ? 29  PRO A CD  1 
ATOM   53   N N   . ASP A 1 30  ? 15.42900 -8.72100  138.12700 1.000 12.46000 ? 30  ASP A N   1 
ATOM   54   C CA  . ASP A 1 30  ? 15.13500 -7.44600  137.47500 1.000 12.56000 ? 30  ASP A CA  1 
ATOM   55   C C   . ASP A 1 30  ? 16.37500 -6.56000  137.41600 1.000 10.45000 ? 30  ASP A C   1 
ATOM   56   O O   . ASP A 1 30  ? 16.58000 -5.83800  136.43200 1.000 11.76000 ? 30  ASP A O   1 
ATOM   57   C CB  . ASP A 1 30  ? 13.94000 -6.73400  138.13900 1.000 11.60000 ? 30  ASP A CB  1 
ATOM   58   C CG  . ASP A 1 30  ? 14.12100 -6.45000  139.63400 1.000 13.51000 ? 30  ASP A CG  1 
ATOM   59   O OD1 . ASP A 1 30  ? 15.13000 -6.83600  140.26300 1.000 14.75000 ? 30  ASP A OD1 1 
ATOM   60   O OD2 . ASP A 1 30  ? 13.20600 -5.80500  140.18100 1.000 12.50000 ? 30  ASP A OD2 1 
ATOM   61   N N   . MET A 1 31  ? 17.23400 -6.63100  138.43400 1.000 8.23000  ? 31  MET A N   1 
ATOM   62   C CA  . MET A 1 31  ? 18.50600 -5.91600  138.39100 1.000 8.30000  ? 31  MET A CA  1 
ATOM   63   C C   . MET A 1 31  ? 19.37600 -6.41400  137.24000 1.000 9.46000  ? 31  MET A C   1 
ATOM   64   O O   . MET A 1 31  ? 19.98600 -5.62400  136.50900 1.000 8.67000  ? 31  MET A O   1 
ATOM   65   C CB  . MET A 1 31  ? 19.23400 -6.08300  139.73100 1.000 7.64000  ? 31  MET A CB  1 
ATOM   66   C CG  . MET A 1 31  ? 20.49700 -5.25000  139.86300 1.000 7.43000  ? 31  MET A CG  1 
ATOM   67   S SD  . MET A 1 31  ? 20.11800 -3.50400  140.17800 1.000 8.69000  ? 31  MET A SD  1 
ATOM   68   C CE  . MET A 1 31  ? 20.68300 -2.74900  138.65200 1.000 6.81000  ? 31  MET A CE  1 
ATOM   69   N N   . LYS A 1 32  ? 19.45200 -7.73300  137.07600 1.000 9.74000  ? 32  LYS A N   1 
ATOM   70   C CA  . LYS A 1 32  ? 20.29300 -8.30300  136.03300 1.000 10.17000 ? 32  LYS A CA  1 
ATOM   71   C C   . LYS A 1 32  ? 19.81000 -7.89200  134.64600 1.000 11.44000 ? 32  LYS A C   1 
ATOM   72   O O   . LYS A 1 32  ? 20.62000 -7.56400  133.76800 1.000 10.84000 ? 32  LYS A O   1 
ATOM   73   C CB  . LYS A 1 32  ? 20.31000 -9.82600  136.17700 1.000 11.37000 ? 32  LYS A CB  1 
ATOM   74   C CG  . LYS A 1 32  ? 21.14000 -10.53400 135.12300 1.000 14.25000 ? 32  LYS A CG  1 
ATOM   75   C CD  . LYS A 1 32  ? 21.37500 -11.98200 135.51600 1.000 19.62000 ? 32  LYS A CD  1 
ATOM   76   C CE  . LYS A 1 32  ? 22.40200 -12.63000 134.58900 1.000 28.38000 ? 32  LYS A CE  1 
ATOM   77   N NZ  . LYS A 1 32  ? 22.32400 -14.11800 134.64700 1.000 35.76000 ? 32  LYS A NZ  1 
ATOM   78   N N   . ALA A 1 33  ? 18.49100 -7.89600  134.43500 1.000 11.49000 ? 33  ALA A N   1 
ATOM   79   C CA  . ALA A 1 33  ? 17.94100 -7.49900  133.14100 1.000 12.91000 ? 33  ALA A CA  1 
ATOM   80   C C   . ALA A 1 33  ? 18.28300 -6.05100  132.81700 1.000 12.18000 ? 33  ALA A C   1 
ATOM   81   O O   . ALA A 1 33  ? 18.57300 -5.71200  131.65900 1.000 12.34000 ? 33  ALA A O   1 
ATOM   82   C CB  . ALA A 1 33  ? 16.42800 -7.70300  133.13800 1.000 15.69000 ? 33  ALA A CB  1 
ATOM   83   N N   . PHE A 1 34  ? 18.25800 -5.18000  133.82900 1.000 11.09000 ? 34  PHE A N   1 
ATOM   84   C CA  . PHE A 1 34  ? 18.61000 -3.78400  133.60400 1.000 10.17000 ? 34  PHE A CA  1 
ATOM   85   C C   . PHE A 1 34  ? 20.08500 -3.63800  133.25200 1.000 9.34000  ? 34  PHE A C   1 
ATOM   86   O O   . PHE A 1 34  ? 20.43900 -2.87900  132.34000 1.000 9.95000  ? 34  PHE A O   1 
ATOM   87   C CB  . PHE A 1 34  ? 18.25900 -2.94700  134.83600 1.000 9.11000  ? 34  PHE A CB  1 
ATOM   88   C CG  . PHE A 1 34  ? 18.54400 -1.48000  134.66800 1.000 10.97000 ? 34  PHE A CG  1 
ATOM   89   C CD1 . PHE A 1 34  ? 17.73000 -0.69300  133.87200 1.000 13.25000 ? 34  PHE A CD1 1 
ATOM   90   C CD2 . PHE A 1 34  ? 19.64000 -0.89600  135.28500 1.000 11.26000 ? 34  PHE A CD2 1 
ATOM   91   C CE1 . PHE A 1 34  ? 18.00000 0.66400   133.70500 1.000 16.77000 ? 34  PHE A CE1 1 
ATOM   92   C CE2 . PHE A 1 34  ? 19.91200 0.46300   135.12100 1.000 13.86000 ? 34  PHE A CE2 1 
ATOM   93   C CZ  . PHE A 1 34  ? 19.08500 1.23700   134.32700 1.000 12.97000 ? 34  PHE A CZ  1 
ATOM   94   N N   . LEU A 1 35  ? 20.96200 -4.35900  133.95600 1.000 8.00000  ? 35  LEU A N   1 
ATOM   95   C CA  . LEU A 1 35  ? 22.38300 -4.30700  133.62300 1.000 9.89000  ? 35  LEU A CA  1 
ATOM   96   C C   . LEU A 1 35  ? 22.63500 -4.82100  132.21000 1.000 9.79000  ? 35  LEU A C   1 
ATOM   97   O O   . LEU A 1 35  ? 23.48400 -4.28200  131.48600 1.000 11.90000 ? 35  LEU A O   1 
ATOM   98   C CB  . LEU A 1 35  ? 23.19700 -5.11400  134.63300 1.000 9.27000  ? 35  LEU A CB  1 
ATOM   99   C CG  . LEU A 1 35  ? 23.20600 -4.57300  136.06900 1.000 8.24000  ? 35  LEU A CG  1 
ATOM   100  C CD1 . LEU A 1 35  ? 24.10000 -5.43300  136.95100 1.000 8.26000  ? 35  LEU A CD1 1 
ATOM   101  C CD2 . LEU A 1 35  ? 23.67900 -3.13500  136.08900 1.000 9.74000  ? 35  LEU A CD2 1 
ATOM   102  N N   . GLU A 1 36  ? 21.91000 -5.86100  131.79900 1.000 11.04000 ? 36  GLU A N   1 
ATOM   103  C CA  . GLU A 1 36  ? 22.10900 -6.38900  130.44900 1.000 11.90000 ? 36  GLU A CA  1 
ATOM   104  C C   . GLU A 1 36  ? 21.69500 -5.36400  129.40300 1.000 13.70000 ? 36  GLU A C   1 
ATOM   105  O O   . GLU A 1 36  ? 22.35000 -5.21900  128.36200 1.000 14.62000 ? 36  GLU A O   1 
ATOM   106  C CB  . GLU A 1 36  ? 21.34200 -7.70100  130.28300 1.000 15.19000 ? 36  GLU A CB  1 
ATOM   107  C CG  . GLU A 1 36  ? 22.06900 -8.87400  130.95600 1.000 19.30000 ? 36  GLU A CG  1 
ATOM   108  C CD  . GLU A 1 36  ? 21.22300 -10.13600 131.06300 1.000 28.80000 ? 36  GLU A CD  1 
ATOM   109  O OE1 . GLU A 1 36  ? 20.01400 -10.08100 130.75900 1.000 31.27000 ? 36  GLU A OE1 1 
ATOM   110  O OE2 . GLU A 1 36  ? 21.77100 -11.18600 131.47000 1.000 32.41000 ? 36  GLU A OE2 1 
ATOM   111  N N   . MET A 1 37  ? 20.62400 -4.62500  129.67700 1.000 12.34000 ? 37  MET A N   1 
ATOM   112  C CA  . MET A 1 37  ? 20.21200 -3.56500  128.77000 1.000 12.19000 ? 37  MET A CA  1 
ATOM   113  C C   . MET A 1 37  ? 21.25200 -2.45300  128.71600 1.000 14.53000 ? 37  MET A C   1 
ATOM   114  O O   . MET A 1 37  ? 21.61600 -1.99000  127.62800 1.000 11.64000 ? 37  MET A O   1 
ATOM   115  C CB  . MET A 1 37  ? 18.85500 -3.02100  129.20100 1.000 12.14000 ? 37  MET A CB  1 
ATOM   116  C CG  . MET A 1 37  ? 18.41300 -1.82100  128.40800 1.000 22.60000 ? 37  MET A CG  1 
ATOM   117  S SD  . MET A 1 37  ? 16.98300 -1.10300  129.20800 1.000 43.34000 ? 37  MET A SD  1 
ATOM   118  C CE  . MET A 1 37  ? 17.73500 0.14100   130.24700 1.000 26.21000 ? 37  MET A CE  1 
ATOM   119  N N   . MET A 1 38  ? 21.76300 -2.02500  129.87600 1.000 12.58000 ? 38  MET A N   1 
ATOM   120  C CA  . MET A 1 38  ? 22.74900 -0.95100  129.88300 1.000 15.51000 ? 38  MET A CA  1 
ATOM   121  C C   . MET A 1 38  ? 24.05100 -1.37100  129.21000 1.000 12.99000 ? 38  MET A C   1 
ATOM   122  O O   . MET A 1 38  ? 24.73200 -0.53100  128.61000 1.000 12.07000 ? 38  MET A O   1 
ATOM   123  C CB  . MET A 1 38  ? 23.01000 -0.48400  131.31600 1.000 16.70000 ? 38  MET A CB  1 
ATOM   124  C CG  . MET A 1 38  ? 21.80900 0.20400   131.94600 1.000 15.22000 ? 38  MET A CG  1 
ATOM   125  S SD  . MET A 1 38  ? 21.32400 1.68700   131.03300 1.000 24.21000 ? 38  MET A SD  1 
ATOM   126  C CE  . MET A 1 38  ? 22.76600 2.71100   131.30600 1.000 30.42000 ? 38  MET A CE  1 
ATOM   127  N N   . ALA A 1 39  ? 24.40900 -2.65600  129.29200 1.000 10.54000 ? 39  ALA A N   1 
ATOM   128  C CA  . ALA A 1 39  ? 25.60800 -3.13600  128.61200 1.000 12.69000 ? 39  ALA A CA  1 
ATOM   129  C C   . ALA A 1 39  ? 25.47500 -3.03200  127.09700 1.000 16.67000 ? 39  ALA A C   1 
ATOM   130  O O   . ALA A 1 39  ? 26.47700 -2.83600  126.39900 1.000 17.60000 ? 39  ALA A O   1 
ATOM   131  C CB  . ALA A 1 39  ? 25.89800 -4.58000  129.01300 1.000 16.30000 ? 39  ALA A CB  1 
ATOM   132  N N   . GLN A 1 40  ? 24.25700 -3.14800  126.57300 1.000 13.18000 ? 40  GLN A N   1 
ATOM   133  C CA  . GLN A 1 40  ? 24.06200 -3.01900  125.13000 1.000 14.74000 ? 40  GLN A CA  1 
ATOM   134  C C   . GLN A 1 40  ? 24.13800 -1.56700  124.66600 1.000 15.05000 ? 40  GLN A C   1 
ATOM   135  O O   . GLN A 1 40  ? 24.51500 -1.30500  123.51300 1.000 15.30000 ? 40  GLN A O   1 
ATOM   136  C CB  . GLN A 1 40  ? 22.72500 -3.65100  124.73600 1.000 13.67000 ? 40  GLN A CB  1 
ATOM   137  C CG  . GLN A 1 40  ? 22.42600 -3.69100  123.22400 1.000 21.83000 ? 40  GLN A CG  1 
ATOM   138  C CD  . GLN A 1 40  ? 23.60700 -4.13800  122.35900 1.000 34.21000 ? 40  GLN A CD  1 
ATOM   139  O OE1 . GLN A 1 40  ? 23.83900 -3.58700  121.27900 1.000 28.57000 ? 40  GLN A OE1 1 
ATOM   140  N NE2 . GLN A 1 40  ? 24.34300 -5.15500  122.81900 1.000 28.65000 ? 40  GLN A NE2 1 
ATOM   141  N N   . VAL A 1 41  ? 23.79000 -0.61700  125.53700 1.000 10.83000 ? 41  VAL A N   1 
ATOM   142  C CA  . VAL A 1 41  ? 23.86100 0.80000   125.18000 1.000 15.94000 ? 41  VAL A CA  1 
ATOM   143  C C   . VAL A 1 41  ? 25.29100 1.19200   124.84100 1.000 18.92000 ? 41  VAL A C   1 
ATOM   144  O O   . VAL A 1 41  ? 25.54800 1.87800   123.84500 1.000 19.01000 ? 41  VAL A O   1 
ATOM   145  C CB  . VAL A 1 41  ? 23.31000 1.66900   126.32600 1.000 17.85000 ? 41  VAL A CB  1 
ATOM   146  C CG1 . VAL A 1 41  ? 23.47300 3.16100   126.00000 1.000 20.56000 ? 41  VAL A CG1 1 
ATOM   147  C CG2 . VAL A 1 41  ? 21.86800 1.32000   126.60200 1.000 16.33000 ? 41  VAL A CG2 1 
ATOM   148  N N   . ASN A 1 42  ? 26.23800 0.76900   125.67500 1.000 22.84000 ? 42  ASN A N   1 
ATOM   149  C CA  . ASN A 1 42  ? 27.65300 1.06800   125.49100 1.000 29.25000 ? 42  ASN A CA  1 
ATOM   150  C C   . ASN A 1 42  ? 27.87600 2.56800   125.26600 1.000 30.52000 ? 42  ASN A C   1 
ATOM   151  O O   . ASN A 1 42  ? 28.45600 3.00200   124.26900 1.000 31.27000 ? 42  ASN A O   1 
ATOM   152  C CB  . ASN A 1 42  ? 28.22600 0.23900   124.34000 1.000 32.66000 ? 42  ASN A CB  1 
ATOM   153  C CG  . ASN A 1 42  ? 29.72600 0.05500   124.44900 1.000 39.52000 ? 42  ASN A CG  1 
ATOM   154  O OD1 . ASN A 1 42  ? 30.24300 -0.34100  125.50000 1.000 36.70000 ? 42  ASN A OD1 1 
ATOM   155  N ND2 . ASN A 1 42  ? 30.43600 0.34400   123.36200 1.000 32.33000 ? 42  ASN A ND2 1 
ATOM   156  N N   . GLY A 1 43  ? 27.38000 3.36000   126.21000 1.000 32.79000 ? 43  GLY A N   1 
ATOM   157  C CA  . GLY A 1 43  ? 27.52300 4.79400   126.14000 1.000 32.39000 ? 43  GLY A CA  1 
ATOM   158  C C   . GLY A 1 43  ? 28.96100 5.21400   126.36200 1.000 33.57000 ? 43  GLY A C   1 
ATOM   159  O O   . GLY A 1 43  ? 29.78800 4.43300   126.84500 1.000 33.00000 ? 43  GLY A O   1 
ATOM   160  N N   . PRO A 1 44  ? 29.28800 6.45900   126.02000 1.000 31.04000 ? 44  PRO A N   1 
ATOM   161  C CA  . PRO A 1 44  ? 30.65800 6.93600   126.21700 1.000 25.23000 ? 44  PRO A CA  1 
ATOM   162  C C   . PRO A 1 44  ? 30.96100 7.11100   127.69300 1.000 26.57000 ? 44  PRO A C   1 
ATOM   163  O O   . PRO A 1 44  ? 30.07100 7.25000   128.53400 1.000 23.26000 ? 44  PRO A O   1 
ATOM   164  C CB  . PRO A 1 44  ? 30.69500 8.28200   125.48200 1.000 27.57000 ? 44  PRO A CB  1 
ATOM   165  C CG  . PRO A 1 44  ? 29.30200 8.50700   124.93300 1.000 32.04000 ? 44  PRO A CG  1 
ATOM   166  C CD  . PRO A 1 44  ? 28.38100 7.53900   125.59900 1.000 31.14000 ? 44  PRO A CD  1 
ATOM   167  N N   . LYS A 1 45  ? 32.25100 7.08500   128.00100 1.000 20.99000 ? 45  LYS A N   1 
ATOM   168  C CA  . LYS A 1 45  ? 32.68600 7.38500   129.35400 1.000 22.81000 ? 45  LYS A CA  1 
ATOM   169  C C   . LYS A 1 45  ? 32.43100 8.85700   129.66700 1.000 17.11000 ? 45  LYS A C   1 
ATOM   170  O O   . LYS A 1 45  ? 32.36300 9.70800   128.77100 1.000 16.23000 ? 45  LYS A O   1 
ATOM   171  C CB  . LYS A 1 45  ? 34.17100 7.04700   129.50700 1.000 20.01000 ? 45  LYS A CB  1 
ATOM   172  C CG  . LYS A 1 45  ? 34.47800 5.55100   129.38900 1.000 28.19000 ? 45  LYS A CG  1 
ATOM   173  C CD  . LYS A 1 45  ? 35.97700 5.29200   129.41000 1.000 35.02000 ? 45  LYS A CD  1 
ATOM   174  C CE  . LYS A 1 45  ? 36.29700 3.81400   129.58200 1.000 38.04000 ? 45  LYS A CE  1 
ATOM   175  N NZ  . LYS A 1 45  ? 35.61300 2.97200   128.56600 1.000 38.03000 ? 45  LYS A NZ  1 
ATOM   176  N N   . LEU A 1 46  ? 32.27200 9.16100   130.95500 1.000 16.95000 ? 46  LEU A N   1 
ATOM   177  C CA  . LEU A 1 46  ? 32.05000 10.55000  131.34500 1.000 19.57000 ? 46  LEU A CA  1 
ATOM   178  C C   . LEU A 1 46  ? 33.22500 11.42700  130.94200 1.000 14.78000 ? 46  LEU A C   1 
ATOM   179  O O   . LEU A 1 46  ? 33.04100 12.59500  130.57800 1.000 18.11000 ? 46  LEU A O   1 
ATOM   180  C CB  . LEU A 1 46  ? 31.79500 10.64600  132.85300 1.000 16.87000 ? 46  LEU A CB  1 
ATOM   181  C CG  . LEU A 1 46  ? 30.58700 9.86000   133.35500 1.000 18.80000 ? 46  LEU A CG  1 
ATOM   182  C CD1 . LEU A 1 46  ? 30.52800 9.91300   134.87600 1.000 18.86000 ? 46  LEU A CD1 1 
ATOM   183  C CD2 . LEU A 1 46  ? 29.29100 10.37700  132.75500 1.000 22.28000 ? 46  LEU A CD2 1 
ATOM   184  N N   . SER A 1 47  ? 34.43800 10.87500  130.98500 1.000 13.46000 ? 47  SER A N   1 
ATOM   185  C CA  . SER A 1 47  ? 35.62300 11.64300  130.62200 1.000 17.06000 ? 47  SER A CA  1 
ATOM   186  C C   . SER A 1 47  ? 35.61400 12.06900  129.15600 1.000 22.95000 ? 47  SER A C   1 
ATOM   187  O O   . SER A 1 47  ? 36.27700 13.05500  128.80600 1.000 25.69000 ? 47  SER A O   1 
ATOM   188  C CB  . SER A 1 47  ? 36.88600 10.83000  130.93100 1.000 19.40000 ? 47  SER A CB  1 
ATOM   189  O OG  . SER A 1 47  ? 36.98500 9.69400   130.09400 1.000 20.98000 ? 47  SER A OG  1 
ATOM   190  N N   . GLU A 1 48  ? 34.86500 11.36400  128.30000 1.000 17.16000 ? 48  GLU A N   1 
ATOM   191  C CA  . GLU A 1 48  ? 34.78800 11.66300  126.87200 1.000 20.11000 ? 48  GLU A CA  1 
ATOM   192  C C   . GLU A 1 48  ? 33.66800 12.63500  126.51500 1.000 20.53000 ? 48  GLU A C   1 
ATOM   193  O O   . GLU A 1 48  ? 33.57400 13.05200  125.35800 1.000 23.22000 ? 48  GLU A O   1 
ATOM   194  C CB  . GLU A 1 48  ? 34.61400 10.36400  126.06800 1.000 22.97000 ? 48  GLU A CB  1 
ATOM   195  C CG  . GLU A 1 48  ? 35.61400 9.27200   126.43000 1.000 28.32000 ? 48  GLU A CG  1 
ATOM   196  C CD  . GLU A 1 48  ? 35.22900 7.88100   125.91000 1.000 37.39000 ? 48  GLU A CD  1 
ATOM   197  O OE1 . GLU A 1 48  ? 34.04100 7.64300   125.58900 1.000 33.71000 ? 48  GLU A OE1 1 
ATOM   198  O OE2 . GLU A 1 48  ? 36.12800 7.01200   125.83900 1.000 44.64000 ? 48  GLU A OE2 1 
ATOM   199  N N   . MET A 1 49  ? 32.83000 13.01600  127.46900 1.000 17.11000 ? 49  MET A N   1 
ATOM   200  C CA  . MET A 1 49  ? 31.73200 13.94100  127.23400 1.000 16.37000 ? 49  MET A CA  1 
ATOM   201  C C   . MET A 1 49  ? 32.10300 15.34800  127.69200 1.000 13.97000 ? 49  MET A C   1 
ATOM   202  O O   . MET A 1 49  ? 32.93400 15.53400  128.58400 1.000 16.28000 ? 49  MET A O   1 
ATOM   203  C CB  . MET A 1 49  ? 30.48100 13.48900  127.99500 1.000 16.66000 ? 49  MET A CB  1 
ATOM   204  C CG  . MET A 1 49  ? 29.96500 12.12500  127.60300 1.000 23.99000 ? 49  MET A CG  1 
ATOM   205  S SD  . MET A 1 49  ? 28.50000 11.72600  128.57600 1.000 26.34000 ? 49  MET A SD  1 
ATOM   206  C CE  . MET A 1 49  ? 29.02600 10.17800  129.27200 1.000 28.71000 ? 49  MET A CE  1 
ATOM   207  N N   . SER A 1 50  ? 31.44100 16.34000  127.10200 1.000 12.93000 ? 50  SER A N   1 
ATOM   208  C CA  . SER A 1 50  ? 31.42600 17.65700  127.71800 1.000 12.57000 ? 50  SER A CA  1 
ATOM   209  C C   . SER A 1 50  ? 30.68300 17.57200  129.05100 1.000 12.03000 ? 50  SER A C   1 
ATOM   210  O O   . SER A 1 50  ? 29.88800 16.65500  129.28500 1.000 10.18000 ? 50  SER A O   1 
ATOM   211  C CB  . SER A 1 50  ? 30.75600 18.67900  126.79800 1.000 16.38000 ? 50  SER A CB  1 
ATOM   212  O OG  . SER A 1 50  ? 29.34200 18.60500  126.89100 1.000 14.37000 ? 50  SER A OG  1 
ATOM   213  N N   . LEU A 1 51  ? 30.95800 18.52900  129.94400 1.000 11.81000 ? 51  LEU A N   1 
ATOM   214  C CA  . LEU A 1 51  ? 30.26000 18.53100  131.23300 1.000 9.78000  ? 51  LEU A CA  1 
ATOM   215  C C   . LEU A 1 51  ? 28.75300 18.67000  131.04500 1.000 11.79000 ? 51  LEU A C   1 
ATOM   216  O O   . LEU A 1 51  ? 27.96800 18.00200  131.73200 1.000 8.56000  ? 51  LEU A O   1 
ATOM   217  C CB  . LEU A 1 51  ? 30.78100 19.65800  132.12600 1.000 9.83000  ? 51  LEU A CB  1 
ATOM   218  C CG  . LEU A 1 51  ? 32.18200 19.46400  132.70500 1.000 12.70000 ? 51  LEU A CG  1 
ATOM   219  C CD1 . LEU A 1 51  ? 32.69000 20.78800  133.28200 1.000 10.84000 ? 51  LEU A CD1 1 
ATOM   220  C CD2 . LEU A 1 51  ? 32.19100 18.35500  133.78300 1.000 13.74000 ? 51  LEU A CD2 1 
ATOM   221  N N   . ASP A 1 52  ? 28.32700 19.53800  130.12300 1.000 11.48000 ? 52  ASP A N   1 
ATOM   222  C CA  . ASP A 1 52  ? 26.89900 19.67100  129.84600 1.000 12.75000 ? 52  ASP A CA  1 
ATOM   223  C C   . ASP A 1 52  ? 26.30800 18.35000  129.36200 1.000 10.76000 ? 52  ASP A C   1 
ATOM   224  O O   . ASP A 1 52  ? 25.20200 17.97100  129.77000 1.000 10.08000 ? 52  ASP A O   1 
ATOM   225  C CB  . ASP A 1 52  ? 26.65800 20.77000  128.80500 1.000 13.43000 ? 52  ASP A CB  1 
ATOM   226  C CG  . ASP A 1 52  ? 26.81400 22.17800  129.37400 1.000 25.56000 ? 52  ASP A CG  1 
ATOM   227  O OD1 . ASP A 1 52  ? 27.12300 22.32100  130.57800 1.000 27.47000 ? 52  ASP A OD1 1 
ATOM   228  O OD2 . ASP A 1 52  ? 26.62700 23.15200  128.60500 1.000 30.22000 ? 52  ASP A OD2 1 
ATOM   229  N N   . GLU A 1 53  ? 27.02800 17.63900  128.48500 1.000 9.54000  ? 53  GLU A N   1 
ATOM   230  C CA  . GLU A 1 53  ? 26.54200 16.35300  127.98800 1.000 12.39000 ? 53  GLU A CA  1 
ATOM   231  C C   . GLU A 1 53  ? 26.47300 15.31700  129.10200 1.000 10.88000 ? 53  GLU A C   1 
ATOM   232  O O   . GLU A 1 53  ? 25.50400 14.55200  129.18500 1.000 9.65000  ? 53  GLU A O   1 
ATOM   233  C CB  . GLU A 1 53  ? 27.43600 15.84000  126.85300 1.000 13.60000 ? 53  GLU A CB  1 
ATOM   234  C CG  . GLU A 1 53  ? 27.27500 16.61500  125.54500 1.000 15.79000 ? 53  GLU A CG  1 
ATOM   235  C CD  . GLU A 1 53  ? 28.38800 16.34000  124.53400 1.000 21.55000 ? 53  GLU A CD  1 
ATOM   236  O OE1 . GLU A 1 53  ? 29.43600 15.76600  124.91100 1.000 16.35000 ? 53  GLU A OE1 1 
ATOM   237  O OE2 . GLU A 1 53  ? 28.20100 16.69800  123.35100 1.000 25.05000 ? 53  GLU A OE2 1 
ATOM   238  N N   . ALA A 1 54  ? 27.51000 15.25800  129.94600 1.000 9.80000  ? 54  ALA A N   1 
ATOM   239  C CA  . ALA A 1 54  ? 27.49800 14.33800  131.08000 1.000 12.61000 ? 54  ALA A CA  1 
ATOM   240  C C   . ALA A 1 54  ? 26.33900 14.64500  132.02000 1.000 9.11000  ? 54  ALA A C   1 
ATOM   241  O O   . ALA A 1 54  ? 25.63100 13.73500  132.46800 1.000 9.26000  ? 54  ALA A O   1 
ATOM   242  C CB  . ALA A 1 54  ? 28.82600 14.41200  131.83300 1.000 10.33000 ? 54  ALA A CB  1 
ATOM   243  N N   . ARG A 1 55  ? 26.12500 15.92300  132.32000 1.000 7.54000  ? 55  ARG A N   1 
ATOM   244  C CA  . ARG A 1 55  ? 25.04700 16.29600  133.22900 1.000 7.94000  ? 55  ARG A CA  1 
ATOM   245  C C   . ARG A 1 55  ? 23.68400 15.99900  132.61800 1.000 10.19000 ? 55  ARG A C   1 
ATOM   246  O O   . ARG A 1 55  ? 22.76600 15.56200  133.32300 1.000 7.95000  ? 55  ARG A O   1 
ATOM   247  C CB  . ARG A 1 55  ? 25.19100 17.76900  133.61600 1.000 8.67000  ? 55  ARG A CB  1 
ATOM   248  C CG  . ARG A 1 55  ? 26.37900 17.97900  134.57400 1.000 7.87000  ? 55  ARG A CG  1 
ATOM   249  C CD  . ARG A 1 55  ? 26.87600 19.41900  134.69300 1.000 7.13000  ? 55  ARG A CD  1 
ATOM   250  N NE  . ARG A 1 55  ? 27.94900 19.47300  135.69300 1.000 7.39000  ? 55  ARG A NE  1 
ATOM   251  C CZ  . ARG A 1 55  ? 28.85400 20.44400  135.78400 1.000 9.55000  ? 55  ARG A CZ  1 
ATOM   252  N NH1 . ARG A 1 55  ? 29.80400 20.38000  136.71400 1.000 6.30000  ? 55  ARG A NH1 1 
ATOM   253  N NH2 . ARG A 1 55  ? 28.80600 21.48000  134.95000 1.000 10.02000 ? 55  ARG A NH2 1 
ATOM   254  N N   . ALA A 1 56  ? 23.53900 16.20300  131.30400 1.000 8.77000  ? 56  ALA A N   1 
ATOM   255  C CA  . ALA A 1 56  ? 22.26600 15.90900  130.64700 1.000 10.54000 ? 56  ALA A CA  1 
ATOM   256  C C   . ALA A 1 56  ? 22.03600 14.40800  130.53500 1.000 10.22000 ? 56  ALA A C   1 
ATOM   257  O O   . ALA A 1 56  ? 20.89600 13.93700  130.63300 1.000 10.20000 ? 56  ALA A O   1 
ATOM   258  C CB  . ALA A 1 56  ? 22.22400 16.55400  129.26200 1.000 10.39000 ? 56  ALA A CB  1 
ATOM   259  N N   . SER A 1 57  ? 23.10900 13.65000  130.30300 1.000 8.77000  ? 57  SER A N   1 
ATOM   260  C CA  . SER A 1 57  ? 23.00600 12.19900  130.21300 1.000 8.07000  ? 57  SER A CA  1 
ATOM   261  C C   . SER A 1 57  ? 22.50900 11.60500  131.52200 1.000 9.74000  ? 57  SER A C   1 
ATOM   262  O O   . SER A 1 57  ? 21.73300 10.64300  131.52700 1.000 8.97000  ? 57  SER A O   1 
ATOM   263  C CB  . SER A 1 57  ? 24.36500 11.61300  129.84200 1.000 12.58000 ? 57  SER A CB  1 
ATOM   264  O OG  . SER A 1 57  ? 24.27200 10.23000  129.56300 1.000 25.31000 ? 57  SER A OG  1 
ATOM   265  N N   . TYR A 1 58  ? 22.94300 12.17500  132.64400 1.000 7.39000  ? 58  TYR A N   1 
ATOM   266  C CA  . TYR A 1 58  ? 22.54700 11.67400  133.95500 1.000 6.28000  ? 58  TYR A CA  1 
ATOM   267  C C   . TYR A 1 58  ? 21.06300 11.91400  134.20700 1.000 6.61000  ? 58  TYR A C   1 
ATOM   268  O O   . TYR A 1 58  ? 20.36400 11.03400  134.72300 1.000 7.25000  ? 58  TYR A O   1 
ATOM   269  C CB  . TYR A 1 58  ? 23.41700 12.36600  135.00800 1.000 6.19000  ? 58  TYR A CB  1 
ATOM   270  C CG  . TYR A 1 58  ? 23.36500 11.80100  136.40900 1.000 9.08000  ? 58  TYR A CG  1 
ATOM   271  C CD1 . TYR A 1 58  ? 23.37600 10.42800  136.64400 1.000 13.67000 ? 58  TYR A CD1 1 
ATOM   272  C CD2 . TYR A 1 58  ? 23.33400 12.65500  137.50200 1.000 7.95000  ? 58  TYR A CD2 1 
ATOM   273  C CE1 . TYR A 1 58  ? 23.34600 9.92600   137.95300 1.000 14.44000 ? 58  TYR A CE1 1 
ATOM   274  C CE2 . TYR A 1 58  ? 23.31800 12.16900  138.80100 1.000 9.43000  ? 58  TYR A CE2 1 
ATOM   275  C CZ  . TYR A 1 58  ? 23.31500 10.81200  139.02000 1.000 9.56000  ? 58  TYR A CZ  1 
ATOM   276  O OH  . TYR A 1 58  ? 23.28900 10.34600  140.31600 1.000 9.62000  ? 58  TYR A OH  1 
ATOM   277  N N   . LEU A 1 59  ? 20.57100 13.10800  133.86600 1.000 6.11000  ? 59  LEU A N   1 
ATOM   278  C CA  . LEU A 1 59  ? 19.13900 13.36400  133.94700 1.000 7.80000  ? 59  LEU A CA  1 
ATOM   279  C C   . LEU A 1 59  ? 18.37300 12.36000  133.09900 1.000 7.90000  ? 59  LEU A C   1 
ATOM   280  O O   . LEU A 1 59  ? 17.36200 11.79700  133.54000 1.000 9.17000  ? 59  LEU A O   1 
ATOM   281  C CB  . LEU A 1 59  ? 18.83600 14.79300  133.49700 1.000 7.19000  ? 59  LEU A CB  1 
ATOM   282  C CG  . LEU A 1 59  ? 17.34000 15.08800  133.37600 1.000 11.15000 ? 59  LEU A CG  1 
ATOM   283  C CD1 . LEU A 1 59  ? 16.70000 15.03200  134.75800 1.000 8.07000  ? 59  LEU A CD1 1 
ATOM   284  C CD2 . LEU A 1 59  ? 17.09100 16.43600  132.70200 1.000 12.60000 ? 59  LEU A CD2 1 
ATOM   285  N N   . ALA A 1 60  ? 18.86100 12.10100  131.88500 1.000 7.48000  ? 60  ALA A N   1 
ATOM   286  C CA  . ALA A 1 60  ? 18.18400 11.15200  131.00400 1.000 8.70000  ? 60  ALA A CA  1 
ATOM   287  C C   . ALA A 1 60  ? 18.13700 9.75600   131.61400 1.000 9.37000  ? 60  ALA A C   1 
ATOM   288  O O   . ALA A 1 60  ? 17.12400 9.05300   131.49500 1.000 11.08000 ? 60  ALA A O   1 
ATOM   289  C CB  . ALA A 1 60  ? 18.87900 11.11900  129.64100 1.000 11.44000 ? 60  ALA A CB  1 
ATOM   290  N N   . MET A 1 61  ? 19.22000 9.33700   132.27500 1.000 8.35000  ? 61  MET A N   1 
ATOM   291  C CA  . MET A 1 61  ? 19.25000 7.99700   132.85200 1.000 10.09000 ? 61  MET A CA  1 
ATOM   292  C C   . MET A 1 61  ? 18.21600 7.85000   133.95800 1.000 10.76000 ? 61  MET A C   1 
ATOM   293  O O   . MET A 1 61  ? 17.53200 6.82400   134.03800 1.000 9.85000  ? 61  MET A O   1 
ATOM   294  C CB  . MET A 1 61  ? 20.64600 7.66200   133.38400 1.000 13.74000 ? 61  MET A CB  1 
ATOM   295  C CG  . MET A 1 61  ? 20.72900 6.25100   133.96800 1.000 25.92000 ? 61  MET A CG  1 
ATOM   296  S SD  . MET A 1 61  ? 22.38700 5.69100   134.41700 1.000 62.04000 ? 61  MET A SD  1 
ATOM   297  C CE  . MET A 1 61  ? 22.19700 5.41600   136.17500 1.000 39.63000 ? 61  MET A CE  1 
ATOM   298  N N   . HIS A 1 62  ? 18.08600 8.86600   134.81700 1.000 9.46000  ? 62  HIS A N   1 
ATOM   299  C CA  . HIS A 1 62  ? 17.09800 8.79800   135.88700 1.000 7.57000  ? 62  HIS A CA  1 
ATOM   300  C C   . HIS A 1 62  ? 15.67600 8.92100   135.34600 1.000 9.85000  ? 62  HIS A C   1 
ATOM   301  O O   . HIS A 1 62  ? 14.76200 8.23900   135.82700 1.000 10.74000 ? 62  HIS A O   1 
ATOM   302  C CB  . HIS A 1 62  ? 17.38700 9.87600   136.92700 1.000 9.75000  ? 62  HIS A CB  1 
ATOM   303  C CG  . HIS A 1 62  ? 18.51600 9.52000   137.84000 1.000 10.81000 ? 62  HIS A CG  1 
ATOM   304  N ND1 . HIS A 1 62  ? 18.82600 10.24900  138.96700 1.000 11.44000 ? 62  HIS A ND1 1 
ATOM   305  C CD2 . HIS A 1 62  ? 19.40000 8.49100   137.80000 1.000 13.24000 ? 62  HIS A CD2 1 
ATOM   306  C CE1 . HIS A 1 62  ? 19.86000 9.69300   139.57700 1.000 12.13000 ? 62  HIS A CE1 1 
ATOM   307  N NE2 . HIS A 1 62  ? 20.22700 8.62600   138.88900 1.000 10.76000 ? 62  HIS A NE2 1 
ATOM   308  N N   . ASN A 1 63  ? 15.46300 9.78400   134.35000 1.000 8.96000  ? 63  ASN A N   1 
ATOM   309  C CA  . ASN A 1 63  ? 14.15200 9.83500   133.70700 1.000 10.07000 ? 63  ASN A CA  1 
ATOM   310  C C   . ASN A 1 63  ? 13.78400 8.49500   133.08700 1.000 13.31000 ? 63  ASN A C   1 
ATOM   311  O O   . ASN A 1 63  ? 12.60700 8.11600   133.08000 1.000 16.93000 ? 63  ASN A O   1 
ATOM   312  C CB  . ASN A 1 63  ? 14.11400 10.92200  132.63100 1.000 12.14000 ? 63  ASN A CB  1 
ATOM   313  C CG  . ASN A 1 63  ? 14.06900 12.32100  133.20600 1.000 14.17000 ? 63  ASN A CG  1 
ATOM   314  O OD1 . ASN A 1 63  ? 13.83400 12.51300  134.39800 1.000 15.33000 ? 63  ASN A OD1 1 
ATOM   315  N ND2 . ASN A 1 63  ? 14.29600 13.31600  132.35300 1.000 13.18000 ? 63  ASN A ND2 1 
ATOM   316  N N   . LEU A 1 64  ? 14.76900 7.76900   132.56000 1.000 8.99000  ? 64  LEU A N   1 
ATOM   317  C CA  . LEU A 1 64  ? 14.49400 6.47700   131.94300 1.000 9.79000  ? 64  LEU A CA  1 
ATOM   318  C C   . LEU A 1 64  ? 14.14200 5.43900   132.99500 1.000 12.61000 ? 64  LEU A C   1 
ATOM   319  O O   . LEU A 1 64  ? 13.13800 4.72900   132.87300 1.000 12.01000 ? 64  LEU A O   1 
ATOM   320  C CB  . LEU A 1 64  ? 15.71000 6.01000   131.14100 1.000 11.73000 ? 64  LEU A CB  1 
ATOM   321  C CG  . LEU A 1 64  ? 15.64400 4.63000   130.48000 1.000 17.58000 ? 64  LEU A CG  1 
ATOM   322  C CD1 . LEU A 1 64  ? 15.06700 4.76800   129.08000 1.000 19.31000 ? 64  LEU A CD1 1 
ATOM   323  C CD2 . LEU A 1 64  ? 17.02000 3.95200   130.42400 1.000 23.79000 ? 64  LEU A CD2 1 
ATOM   324  N N   . ALA A 1 65  ? 14.96600 5.34200   134.03900 1.000 9.28000  ? 65  ALA A N   1 
ATOM   325  C CA  . ALA A 1 65  ? 14.93800 4.20300   134.94300 1.000 8.46000  ? 65  ALA A CA  1 
ATOM   326  C C   . ALA A 1 65  ? 14.06100 4.40900   136.16900 1.000 7.11000  ? 65  ALA A C   1 
ATOM   327  O O   . ALA A 1 65  ? 13.64700 3.41900   136.77900 1.000 9.15000  ? 65  ALA A O   1 
ATOM   328  C CB  . ALA A 1 65  ? 16.36100 3.87700   135.41300 1.000 12.09000 ? 65  ALA A CB  1 
ATOM   329  N N   . ASP A 1 66  ? 13.77900 5.64700   136.56200 1.000 7.88000  ? 66  ASP A N   1 
ATOM   330  C CA  . ASP A 1 66  ? 13.08700 5.87500   137.82600 1.000 8.60000  ? 66  ASP A CA  1 
ATOM   331  C C   . ASP A 1 66  ? 11.58800 6.06700   137.61800 1.000 9.81000  ? 66  ASP A C   1 
ATOM   332  O O   . ASP A 1 66  ? 11.11700 6.37000   136.52100 1.000 10.14000 ? 66  ASP A O   1 
ATOM   333  C CB  . ASP A 1 66  ? 13.65800 7.09100   138.55900 1.000 9.51000  ? 66  ASP A CB  1 
ATOM   334  C CG  . ASP A 1 66  ? 13.52300 6.97100   140.06900 1.000 12.88000 ? 66  ASP A CG  1 
ATOM   335  O OD1 . ASP A 1 66  ? 13.17900 5.86300   140.54500 1.000 9.80000  ? 66  ASP A OD1 1 
ATOM   336  O OD2 . ASP A 1 66  ? 13.76000 7.97200   140.78200 1.000 9.75000  ? 66  ASP A OD2 1 
ATOM   337  N N   . ARG A 1 67  ? 10.83800 5.88300   138.70800 1.000 7.99000  ? 67  ARG A N   1 
ATOM   338  C CA  . ARG A 1 67  ? 9.41800  6.19200   138.70400 1.000 8.60000  ? 67  ARG A CA  1 
ATOM   339  C C   . ARG A 1 67  ? 9.20000  7.67700   138.45600 1.000 9.35000  ? 67  ARG A C   1 
ATOM   340  O O   . ARG A 1 67  ? 10.07300 8.49900   138.74400 1.000 9.54000  ? 67  ARG A O   1 
ATOM   341  C CB  . ARG A 1 67  ? 8.79400  5.82100   140.04000 1.000 10.62000 ? 67  ARG A CB  1 
ATOM   342  C CG  . ARG A 1 67  ? 8.80300  4.36700   140.25500 1.000 11.54000 ? 67  ARG A CG  1 
ATOM   343  C CD  . ARG A 1 67  ? 7.49900  3.82500   139.90100 1.000 31.37000 ? 67  ARG A CD  1 
ATOM   344  N NE  . ARG A 1 67  ? 6.71300  3.54400   141.09400 1.000 32.60000 ? 67  ARG A NE  1 
ATOM   345  C CZ  . ARG A 1 67  ? 6.73000  2.37500   141.72000 1.000 32.28000 ? 67  ARG A CZ  1 
ATOM   346  N NH1 . ARG A 1 67  ? 7.50600  1.39600   141.27200 1.000 38.46000 ? 67  ARG A NH1 1 
ATOM   347  N NH2 . ARG A 1 67  ? 5.96600  2.17700   142.78300 1.000 27.58000 ? 67  ARG A NH2 1 
ATOM   348  N N   . PRO A 1 68  ? 8.03500  8.04700   137.93500 1.000 8.09000  ? 68  PRO A N   1 
ATOM   349  C CA  . PRO A 1 68  ? 7.74300  9.47100   137.75100 1.000 11.11000 ? 68  PRO A CA  1 
ATOM   350  C C   . PRO A 1 68  ? 7.58500  10.17600  139.09100 1.000 10.05000 ? 68  PRO A C   1 
ATOM   351  O O   . PRO A 1 68  ? 7.27400  9.57000   140.12200 1.000 9.83000  ? 68  PRO A O   1 
ATOM   352  C CB  . PRO A 1 68  ? 6.43100  9.48000   136.95700 1.000 17.34000 ? 68  PRO A CB  1 
ATOM   353  C CG  . PRO A 1 68  ? 5.84600  8.12600   137.12000 1.000 17.06000 ? 68  PRO A CG  1 
ATOM   354  C CD  . PRO A 1 68  ? 6.97400  7.17400   137.39900 1.000 16.87000 ? 68  PRO A CD  1 
ATOM   355  N N   . ALA A 1 69  ? 7.82500  11.48400  139.05700 1.000 8.71000  ? 69  ALA A N   1 
ATOM   356  C CA  . ALA A 1 69  ? 7.64600  12.30600  140.24300 1.000 10.77000 ? 69  ALA A CA  1 
ATOM   357  C C   . ALA A 1 69  ? 6.18500  12.30400  140.67000 1.000 13.00000 ? 69  ALA A C   1 
ATOM   358  O O   . ALA A 1 69  ? 5.26700  12.23300  139.84400 1.000 13.79000 ? 69  ALA A O   1 
ATOM   359  C CB  . ALA A 1 69  ? 8.10600  13.73800  139.96900 1.000 11.98000 ? 69  ALA A CB  1 
ATOM   360  N N   . ARG A 1 70  ? 5.97100  12.36500  141.97600 1.000 10.55000 ? 70  ARG A N   1 
ATOM   361  C CA  . ARG A 1 70  ? 4.62800  12.55300  142.49500 1.000 12.44000 ? 70  ARG A CA  1 
ATOM   362  C C   . ARG A 1 70  ? 4.20700  14.00900  142.38000 1.000 12.41000 ? 70  ARG A C   1 
ATOM   363  O O   . ARG A 1 70  ? 5.02200  14.93000  142.51700 1.000 11.38000 ? 70  ARG A O   1 
ATOM   364  C CB  . ARG A 1 70  ? 4.54700  12.13400  143.95900 1.000 10.35000 ? 70  ARG A CB  1 
ATOM   365  C CG  . ARG A 1 70  ? 4.96500  10.71400  144.21300 1.000 13.25000 ? 70  ARG A CG  1 
ATOM   366  C CD  . ARG A 1 70  ? 4.68700  10.36300  145.65400 1.000 13.06000 ? 70  ARG A CD  1 
ATOM   367  N NE  . ARG A 1 70  ? 4.99000  8.96500   145.93400 1.000 16.61000 ? 70  ARG A NE  1 
ATOM   368  C CZ  . ARG A 1 70  ? 4.22700  8.18600   146.69200 1.000 19.37000 ? 70  ARG A CZ  1 
ATOM   369  N NH1 . ARG A 1 70  ? 3.12200  8.68000   147.23400 1.000 15.81000 ? 70  ARG A NH1 1 
ATOM   370  N NH2 . ARG A 1 70  ? 4.56600  6.91700   146.89900 1.000 15.53000 ? 70  ARG A NH2 1 
ATOM   371  N N   . ALA A 1 71  ? 2.91300  14.21200  142.14600 1.000 10.29000 ? 71  ALA A N   1 
ATOM   372  C CA  . ALA A 1 71  ? 2.34700  15.54600  142.26300 1.000 12.59000 ? 71  ALA A CA  1 
ATOM   373  C C   . ALA A 1 71  ? 2.23500  15.90900  143.74000 1.000 14.23000 ? 71  ALA A C   1 
ATOM   374  O O   . ALA A 1 71  ? 1.78100  15.09800  144.55400 1.000 17.09000 ? 71  ALA A O   1 
ATOM   375  C CB  . ALA A 1 71  ? 0.97700  15.61000  141.58600 1.000 16.06000 ? 71  ALA A CB  1 
ATOM   376  N N   . LEU A 1 72  ? 2.68900  17.10600  144.09200 1.000 11.06000 ? 72  LEU A N   1 
ATOM   377  C CA  . LEU A 1 72  ? 2.62900  17.59300  145.46100 1.000 10.72000 ? 72  LEU A CA  1 
ATOM   378  C C   . LEU A 1 72  ? 2.09200  19.01300  145.44900 1.000 10.70000 ? 72  LEU A C   1 
ATOM   379  O O   . LEU A 1 72  ? 2.26100  19.73000  144.45700 1.000 11.11000 ? 72  LEU A O   1 
ATOM   380  C CB  . LEU A 1 72  ? 4.01200  17.58500  146.13300 1.000 10.06000 ? 72  LEU A CB  1 
ATOM   381  C CG  . LEU A 1 72  ? 4.79100  16.26800  146.18500 1.000 9.22000  ? 72  LEU A CG  1 
ATOM   382  C CD1 . LEU A 1 72  ? 6.21200  16.51700  146.70600 1.000 11.50000 ? 72  LEU A CD1 1 
ATOM   383  C CD2 . LEU A 1 72  ? 4.07300  15.24300  147.04400 1.000 11.63000 ? 72  LEU A CD2 1 
ATOM   384  N N   . PRO A 1 73  ? 1.46500  19.46000  146.54200 1.000 10.79000 ? 73  PRO A N   1 
ATOM   385  C CA  . PRO A 1 73  ? 1.00800  20.85600  146.58600 1.000 10.52000 ? 73  PRO A CA  1 
ATOM   386  C C   . PRO A 1 73  ? 2.13700  21.84900  146.70000 1.000 9.46000  ? 73  PRO A C   1 
ATOM   387  O O   . PRO A 1 73  ? 1.95400  23.00900  146.31400 1.000 10.21000 ? 73  PRO A O   1 
ATOM   388  C CB  . PRO A 1 73  ? 0.11000  20.90200  147.82700 1.000 9.48000  ? 73  PRO A CB  1 
ATOM   389  C CG  . PRO A 1 73  ? 0.59300  19.77400  148.68500 1.000 9.99000  ? 73  PRO A CG  1 
ATOM   390  C CD  . PRO A 1 73  ? 1.03000  18.69600  147.72300 1.000 9.29000  ? 73  PRO A CD  1 
ATOM   391  N N   . VAL A 1 74  ? 3.29000  21.44600  147.23000 1.000 9.51000  ? 74  VAL A N   1 
ATOM   392  C CA  . VAL A 1 74  ? 4.41100  22.35100  147.44900 1.000 9.64000  ? 74  VAL A CA  1 
ATOM   393  C C   . VAL A 1 74  ? 5.63000  21.76600  146.75200 1.000 9.69000  ? 74  VAL A C   1 
ATOM   394  O O   . VAL A 1 74  ? 6.21200  20.78000  147.22500 1.000 9.07000  ? 74  VAL A O   1 
ATOM   395  C CB  . VAL A 1 74  ? 4.69800  22.57400  148.94000 1.000 11.62000 ? 74  VAL A CB  1 
ATOM   396  C CG1 . VAL A 1 74  ? 5.95400  23.43200  149.10800 1.000 14.22000 ? 74  VAL A CG1 1 
ATOM   397  C CG2 . VAL A 1 74  ? 3.50900  23.21100  149.63200 1.000 10.87000 ? 74  VAL A CG2 1 
ATOM   398  N N   . ILE A 1 75  ? 5.99400  22.34400  145.61000 1.000 9.40000  ? 75  ILE A N   1 
ATOM   399  C CA  . ILE A 1 75  ? 7.28500  22.09500  144.98200 1.000 9.07000  ? 75  ILE A CA  1 
ATOM   400  C C   . ILE A 1 75  ? 7.76200  23.46400  144.52600 1.000 12.42000 ? 75  ILE A C   1 
ATOM   401  O O   . ILE A 1 75  ? 7.29000  23.99200  143.51500 1.000 14.33000 ? 75  ILE A O   1 
ATOM   402  C CB  . ILE A 1 75  ? 7.20900  21.09400  143.81300 1.000 10.22000 ? 75  ILE A CB  1 
ATOM   403  C CG1 . ILE A 1 75  ? 6.67100  19.73600  144.27000 1.000 10.58000 ? 75  ILE A CG1 1 
ATOM   404  C CG2 . ILE A 1 75  ? 8.59000  20.91100  143.19100 1.000 11.16000 ? 75  ILE A CG2 1 
ATOM   405  C CD1 . ILE A 1 75  ? 6.51000  18.71300  143.12400 1.000 11.52000 ? 75  ILE A CD1 1 
ATOM   406  N N   . ARG A 1 76  ? 8.67100  24.06500  145.28500 1.000 8.65000  ? 76  ARG A N   1 
ATOM   407  C CA  . ARG A 1 76  ? 8.94100  25.49000  145.16300 1.000 12.46000 ? 76  ARG A CA  1 
ATOM   408  C C   . ARG A 1 76  ? 10.43700 25.74700  145.07300 1.000 13.32000 ? 76  ARG A C   1 
ATOM   409  O O   . ARG A 1 76  ? 11.20100 25.29100  145.93000 1.000 10.53000 ? 76  ARG A O   1 
ATOM   410  C CB  . ARG A 1 76  ? 8.33400  26.23300  146.35900 1.000 16.28000 ? 76  ARG A CB  1 
ATOM   411  C CG  . ARG A 1 76  ? 8.57500  27.71900  146.37400 1.000 25.16000 ? 76  ARG A CG  1 
ATOM   412  C CD  . ARG A 1 76  ? 7.50800  28.40800  147.20500 1.000 21.50000 ? 76  ARG A CD  1 
ATOM   413  N NE  . ARG A 1 76  ? 7.69200  28.17900  148.63200 1.000 22.43000 ? 76  ARG A NE  1 
ATOM   414  C CZ  . ARG A 1 76  ? 8.55100  28.85600  149.38900 1.000 27.96000 ? 76  ARG A CZ  1 
ATOM   415  N NH1 . ARG A 1 76  ? 8.65300  28.58900  150.68600 1.000 25.16000 ? 76  ARG A NH1 1 
ATOM   416  N NH2 . ARG A 1 76  ? 9.30800  29.80200  148.84900 1.000 27.82000 ? 76  ARG A NH2 1 
ATOM   417  N N   . ASP A 1 77  ? 10.84800 26.49200  144.04500 1.000 10.85000 ? 77  ASP A N   1 
ATOM   418  C CA  . ASP A 1 77  ? 12.24000 26.89900  143.91600 1.000 11.83000 ? 77  ASP A CA  1 
ATOM   419  C C   . ASP A 1 77  ? 12.50100 28.14900  144.74200 1.000 15.67000 ? 77  ASP A C   1 
ATOM   420  O O   . ASP A 1 77  ? 11.69200 29.08200  144.75500 1.000 15.15000 ? 77  ASP A O   1 
ATOM   421  C CB  . ASP A 1 77  ? 12.59700 27.17300  142.45200 1.000 14.52000 ? 77  ASP A CB  1 
ATOM   422  C CG  . ASP A 1 77  ? 12.53300 25.92600  141.58900 1.000 23.80000 ? 77  ASP A CG  1 
ATOM   423  O OD1 . ASP A 1 77  ? 13.14700 24.90900  141.96700 1.000 19.65000 ? 77  ASP A OD1 1 
ATOM   424  O OD2 . ASP A 1 77  ? 11.86800 25.96500  140.52900 1.000 32.59000 ? 77  ASP A OD2 1 
ATOM   425  N N   . LEU A 1 78  ? 13.63800 28.16900  145.42800 1.000 10.65000 ? 78  LEU A N   1 
ATOM   426  C CA  . LEU A 1 78  ? 14.05900 29.34200  146.18500 1.000 12.78000 ? 78  LEU A CA  1 
ATOM   427  C C   . LEU A 1 78  ? 15.57500 29.29900  146.31500 1.000 14.45000 ? 78  LEU A C   1 
ATOM   428  O O   . LEU A 1 78  ? 16.23300 28.38300  145.81800 1.000 12.89000 ? 78  LEU A O   1 
ATOM   429  C CB  . LEU A 1 78  ? 13.37200 29.40800  147.55400 1.000 12.28000 ? 78  LEU A CB  1 
ATOM   430  C CG  . LEU A 1 78  ? 13.78100 28.37600  148.61200 1.000 12.91000 ? 78  LEU A CG  1 
ATOM   431  C CD1 . LEU A 1 78  ? 13.52300 28.92900  150.00800 1.000 15.13000 ? 78  LEU A CD1 1 
ATOM   432  C CD2 . LEU A 1 78  ? 13.03300 27.06500  148.41800 1.000 10.71000 ? 78  LEU A CD2 1 
ATOM   433  N N   . SER A 1 79  ? 16.13000 30.30600  146.98200 1.000 12.10000 ? 79  SER A N   1 
ATOM   434  C CA  . SER A 1 79  ? 17.56900 30.39000  147.16300 1.000 12.89000 ? 79  SER A CA  1 
ATOM   435  C C   . SER A 1 79  ? 17.88100 30.79700  148.59400 1.000 14.59000 ? 79  SER A C   1 
ATOM   436  O O   . SER A 1 79  ? 17.02900 31.31600  149.31700 1.000 17.68000 ? 79  SER A O   1 
ATOM   437  C CB  . SER A 1 79  ? 18.19800 31.38600  146.17500 1.000 16.59000 ? 79  SER A CB  1 
ATOM   438  O OG  . SER A 1 79  ? 17.93700 32.71900  146.57600 1.000 23.98000 ? 79  SER A OG  1 
ATOM   439  N N   . CYS A 1 80  ? 19.12200 30.57000  148.99700 1.000 12.07000 ? 80  CYS A N   1 
ATOM   440  C CA  . CYS A 1 80  ? 19.58900 31.05600  150.28400 1.000 13.09000 ? 80  CYS A CA  1 
ATOM   441  C C   . CYS A 1 80  ? 20.99500 31.60100  150.11600 1.000 14.88000 ? 80  CYS A C   1 
ATOM   442  O O   . CYS A 1 80  ? 21.68500 31.27100  149.14300 1.000 14.22000 ? 80  CYS A O   1 
ATOM   443  C CB  . CYS A 1 80  ? 19.54600 29.95200  151.35200 1.000 12.63000 ? 80  CYS A CB  1 
ATOM   444  S SG  . CYS A 1 80  ? 20.78600 28.64800  151.20600 1.000 14.00000 ? 80  CYS A SG  1 
ATOM   445  N N   . PRO A 1 81  ? 21.43800 32.47400  151.02200 1.000 12.53000 ? 81  PRO A N   1 
ATOM   446  C CA  . PRO A 1 81  ? 22.81000 32.98400  150.94200 1.000 14.89000 ? 81  PRO A CA  1 
ATOM   447  C C   . PRO A 1 81  ? 23.82400 31.88100  151.20800 1.000 14.73000 ? 81  PRO A C   1 
ATOM   448  O O   . PRO A 1 81  ? 23.67400 31.08500  152.13800 1.000 19.05000 ? 81  PRO A O   1 
ATOM   449  C CB  . PRO A 1 81  ? 22.86500 34.05900  152.03800 1.000 15.75000 ? 81  PRO A CB  1 
ATOM   450  C CG  . PRO A 1 81  ? 21.45000 34.33200  152.41700 1.000 19.31000 ? 81  PRO A CG  1 
ATOM   451  C CD  . PRO A 1 81  ? 20.67800 33.08500  152.13100 1.000 14.73000 ? 81  PRO A CD  1 
ATOM   452  N N   . GLY A 1 82  ? 24.86600 31.84800  150.38700 1.000 15.31000 ? 82  GLY A N   1 
ATOM   453  C CA  . GLY A 1 82  ? 25.95000 30.91200  150.56600 1.000 13.15000 ? 82  GLY A CA  1 
ATOM   454  C C   . GLY A 1 82  ? 27.28100 31.63100  150.59100 1.000 17.82000 ? 82  GLY A C   1 
ATOM   455  O O   . GLY A 1 82  ? 27.34600 32.85400  150.42300 1.000 17.60000 ? 82  GLY A O   1 
ATOM   456  N N   . PRO A 1 83  ? 28.37200 30.89000  150.80600 1.000 15.66000 ? 83  PRO A N   1 
ATOM   457  C CA  . PRO A 1 83  ? 29.69500 31.53600  150.87700 1.000 19.10000 ? 83  PRO A CA  1 
ATOM   458  C C   . PRO A 1 83  ? 30.11600 32.22600  149.58900 1.000 20.68000 ? 83  PRO A C   1 
ATOM   459  O O   . PRO A 1 83  ? 30.91300 33.17100  149.64800 1.000 19.49000 ? 83  PRO A O   1 
ATOM   460  C CB  . PRO A 1 83  ? 30.64100 30.37700  151.22100 1.000 21.56000 ? 83  PRO A CB  1 
ATOM   461  C CG  . PRO A 1 83  ? 29.86800 29.12000  150.92500 1.000 19.00000 ? 83  PRO A CG  1 
ATOM   462  C CD  . PRO A 1 83  ? 28.43100 29.45400  151.13900 1.000 14.83000 ? 83  PRO A CD  1 
ATOM   463  N N   . LYS A 1 84  ? 29.60200 31.80600  148.43300 1.000 17.75000 ? 84  LYS A N   1 
ATOM   464  C CA  . LYS A 1 84  ? 30.02100 32.37900  147.15800 1.000 22.00000 ? 84  LYS A CA  1 
ATOM   465  C C   . LYS A 1 84  ? 28.89200 33.05600  146.38900 1.000 22.25000 ? 84  LYS A C   1 
ATOM   466  O O   . LYS A 1 84  ? 29.09700 33.45000  145.23400 1.000 27.52000 ? 84  LYS A O   1 
ATOM   467  C CB  . LYS A 1 84  ? 30.65900 31.30100  146.27900 1.000 23.10000 ? 84  LYS A CB  1 
ATOM   468  C CG  . LYS A 1 84  ? 31.84900 30.59500  146.90500 1.000 28.02000 ? 84  LYS A CG  1 
ATOM   469  C CD  . LYS A 1 84  ? 32.77500 31.58100  147.61400 1.000 36.26000 ? 84  LYS A CD  1 
ATOM   470  C CE  . LYS A 1 84  ? 33.99900 31.90600  146.77300 1.000 36.67000 ? 84  LYS A CE  1 
ATOM   471  N NZ  . LYS A 1 84  ? 34.72900 33.10600  147.29700 1.000 39.48000 ? 84  LYS A NZ  1 
ATOM   472  N N   . GLY A 1 85  ? 27.73000 33.22500  146.98900 1.000 16.85000 ? 85  GLY A N   1 
ATOM   473  C CA  . GLY A 1 85  ? 26.56100 33.71300  146.29700 1.000 18.75000 ? 85  GLY A CA  1 
ATOM   474  C C   . GLY A 1 85  ? 25.35300 32.91100  146.72500 1.000 19.20000 ? 85  GLY A C   1 
ATOM   475  O O   . GLY A 1 85  ? 25.39500 32.17000  147.70700 1.000 19.35000 ? 85  GLY A O   1 
ATOM   476  N N   . GLU A 1 86  ? 24.26200 33.04900  145.98400 1.000 15.02000 ? 86  GLU A N   1 
ATOM   477  C CA  . GLU A 1 86  ? 23.05000 32.33400  146.35800 1.000 15.38000 ? 86  GLU A CA  1 
ATOM   478  C C   . GLU A 1 86  ? 23.19100 30.85600  146.01500 1.000 14.07000 ? 86  GLU A C   1 
ATOM   479  O O   . GLU A 1 86  ? 23.83400 30.49000  145.02700 1.000 11.29000 ? 86  GLU A O   1 
ATOM   480  C CB  . GLU A 1 86  ? 21.82500 32.93400  145.66300 1.000 19.92000 ? 86  GLU A CB  1 
ATOM   481  C CG  . GLU A 1 86  ? 21.45600 34.35900  146.13100 1.000 25.41000 ? 86  GLU A CG  1 
ATOM   482  C CD  . GLU A 1 86  ? 20.90000 34.41400  147.55800 1.000 31.96000 ? 86  GLU A CD  1 
ATOM   483  O OE1 . GLU A 1 86  ? 21.49700 35.11800  148.41200 1.000 34.28000 ? 86  GLU A OE1 1 
ATOM   484  O OE2 . GLU A 1 86  ? 19.86000 33.76500  147.82800 1.000 29.79000 ? 86  GLU A OE2 1 
ATOM   485  N N   . ILE A 1 87  ? 22.62400 30.00500  146.86700 1.000 11.38000 ? 87  ILE A N   1 
ATOM   486  C CA  . ILE A 1 87  ? 22.54400 28.56600  146.63100 1.000 9.21000  ? 87  ILE A CA  1 
ATOM   487  C C   . ILE A 1 87  ? 21.10000 28.25300  146.26700 1.000 8.25000  ? 87  ILE A C   1 
ATOM   488  O O   . ILE A 1 87  ? 20.18500 28.56600  147.03900 1.000 9.77000  ? 87  ILE A O   1 
ATOM   489  C CB  . ILE A 1 87  ? 22.97500 27.75800  147.86900 1.000 10.65000 ? 87  ILE A CB  1 
ATOM   490  C CG1 . ILE A 1 87  ? 24.42700 28.06600  148.25600 1.000 10.00000 ? 87  ILE A CG1 1 
ATOM   491  C CG2 . ILE A 1 87  ? 22.77400 26.25500  147.61600 1.000 7.03000  ? 87  ILE A CG2 1 
ATOM   492  C CD1 . ILE A 1 87  ? 24.79600 27.59500  149.65100 1.000 11.28000 ? 87  ILE A CD1 1 
ATOM   493  N N   . ALA A 1 88  ? 20.88800 27.63900  145.10200 1.000 8.46000  ? 88  ALA A N   1 
ATOM   494  C CA  . ALA A 1 88  ? 19.53700 27.28900  144.69100 1.000 11.88000 ? 88  ALA A CA  1 
ATOM   495  C C   . ALA A 1 88  ? 19.04200 26.07500  145.47200 1.000 8.64000  ? 88  ALA A C   1 
ATOM   496  O O   . ALA A 1 88  ? 19.78100 25.11100  145.68500 1.000 8.24000  ? 88  ALA A O   1 
ATOM   497  C CB  . ALA A 1 88  ? 19.48300 27.01600  143.18800 1.000 12.95000 ? 88  ALA A CB  1 
ATOM   498  N N   . LEU A 1 89  ? 17.78200 26.14200  145.90400 1.000 9.24000  ? 89  LEU A N   1 
ATOM   499  C CA  . LEU A 1 89  ? 17.12700 25.09900  146.68500 1.000 8.19000  ? 89  LEU A CA  1 
ATOM   500  C C   . LEU A 1 89  ? 15.77400 24.77700  146.06700 1.000 9.36000  ? 89  LEU A C   1 
ATOM   501  O O   . LEU A 1 89  ? 15.22100 25.55700  145.28500 1.000 9.35000  ? 89  LEU A O   1 
ATOM   502  C CB  . LEU A 1 89  ? 16.91100 25.53200  148.14800 1.000 8.24000  ? 89  LEU A CB  1 
ATOM   503  C CG  . LEU A 1 89  ? 18.07900 26.18600  148.89000 1.000 7.46000  ? 89  LEU A CG  1 
ATOM   504  C CD1 . LEU A 1 89  ? 17.59200 26.77400  150.21800 1.000 9.22000  ? 89  LEU A CD1 1 
ATOM   505  C CD2 . LEU A 1 89  ? 19.17600 25.16100  149.12400 1.000 7.36000  ? 89  LEU A CD2 1 
ATOM   506  N N   . ARG A 1 90  ? 15.22300 23.62500  146.44400 1.000 8.54000  ? 90  ARG A N   1 
ATOM   507  C CA  . ARG A 1 90  ? 13.86600 23.27100  146.04500 1.000 7.32000  ? 90  ARG A CA  1 
ATOM   508  C C   . ARG A 1 90  ? 13.17100 22.64600  147.24300 1.000 7.75000  ? 90  ARG A C   1 
ATOM   509  O O   . ARG A 1 90  ? 13.68200 21.68900  147.83100 1.000 5.85000  ? 90  ARG A O   1 
ATOM   510  C CB  . ARG A 1 90  ? 13.85200 22.31300  144.84800 1.000 6.65000  ? 90  ARG A CB  1 
ATOM   511  C CG  . ARG A 1 90  ? 12.44300 22.12700  144.26400 1.000 8.41000  ? 90  ARG A CG  1 
ATOM   512  C CD  . ARG A 1 90  ? 12.44400 21.38800  142.92600 1.000 9.32000  ? 90  ARG A CD  1 
ATOM   513  N NE  . ARG A 1 90  ? 13.08600 22.16000  141.86100 1.000 10.98000 ? 90  ARG A NE  1 
ATOM   514  C CZ  . ARG A 1 90  ? 13.57200 21.62800  140.74200 1.000 13.73000 ? 90  ARG A CZ  1 
ATOM   515  N NH1 . ARG A 1 90  ? 14.14800 22.40600  139.83200 1.000 12.76000 ? 90  ARG A NH1 1 
ATOM   516  N NH2 . ARG A 1 90  ? 13.48000 20.32200  140.52600 1.000 11.29000 ? 90  ARG A NH2 1 
ATOM   517  N N   . LEU A 1 91  ? 12.01900 23.19800  147.60900 1.000 8.39000  ? 91  LEU A N   1 
ATOM   518  C CA  . LEU A 1 91  ? 11.24700 22.72200  148.74800 1.000 6.73000  ? 91  LEU A CA  1 
ATOM   519  C C   . LEU A 1 91  ? 10.12700 21.81300  148.26300 1.000 7.66000  ? 91  LEU A C   1 
ATOM   520  O O   . LEU A 1 91  ? 9.39100  22.17000  147.33400 1.000 9.80000  ? 91  LEU A O   1 
ATOM   521  C CB  . LEU A 1 91  ? 10.67000 23.89700  149.53800 1.000 5.90000  ? 91  LEU A CB  1 
ATOM   522  C CG  . LEU A 1 91  ? 9.60100  23.58000  150.59400 1.000 8.93000  ? 91  LEU A CG  1 
ATOM   523  C CD1 . LEU A 1 91  ? 10.17400 22.77100  151.77200 1.000 8.23000  ? 91  LEU A CD1 1 
ATOM   524  C CD2 . LEU A 1 91  ? 8.95200  24.88300  151.09000 1.000 10.14000 ? 91  LEU A CD2 1 
ATOM   525  N N   . TYR A 1 92  ? 9.99300  20.65700  148.91400 1.000 5.23000  ? 92  TYR A N   1 
ATOM   526  C CA  . TYR A 1 92  ? 8.99000  19.64200  148.61500 1.000 6.61000  ? 92  TYR A CA  1 
ATOM   527  C C   . TYR A 1 92  ? 8.15400  19.39900  149.86200 1.000 8.39000  ? 92  TYR A C   1 
ATOM   528  O O   . TYR A 1 92  ? 8.70800  19.19600  150.94600 1.000 7.71000  ? 92  TYR A O   1 
ATOM   529  C CB  . TYR A 1 92  ? 9.63800  18.31300  148.21600 1.000 6.31000  ? 92  TYR A CB  1 
ATOM   530  C CG  . TYR A 1 92  ? 10.51600 18.30700  146.98200 1.000 7.40000  ? 92  TYR A CG  1 
ATOM   531  C CD1 . TYR A 1 92  ? 11.82000 18.79200  147.03000 1.000 7.91000  ? 92  TYR A CD1 1 
ATOM   532  C CD2 . TYR A 1 92  ? 10.06100 17.75600  145.78900 1.000 5.69000  ? 92  TYR A CD2 1 
ATOM   533  C CE1 . TYR A 1 92  ? 12.64400 18.76000  145.91000 1.000 6.78000  ? 92  TYR A CE1 1 
ATOM   534  C CE2 . TYR A 1 92  ? 10.88600 17.72100  144.65100 1.000 9.22000  ? 92  TYR A CE2 1 
ATOM   535  C CZ  . TYR A 1 92  ? 12.16800 18.22600  144.73000 1.000 6.54000  ? 92  TYR A CZ  1 
ATOM   536  O OH  . TYR A 1 92  ? 12.99100 18.19100  143.62900 1.000 8.43000  ? 92  TYR A OH  1 
ATOM   537  N N   . ASP A 1 93  ? 6.82800  19.37300  149.71400 1.000 7.50000  ? 93  ASP A N   1 
ATOM   538  C CA  . ASP A 1 93  ? 5.98000  19.02900  150.87200 1.000 7.14000  ? 93  ASP A CA  1 
ATOM   539  C C   . ASP A 1 93  ? 4.68500  18.40900  150.36800 1.000 6.04000  ? 93  ASP A C   1 
ATOM   540  O O   . ASP A 1 93  ? 4.01200  19.02500  149.51900 1.000 8.78000  ? 93  ASP A O   1 
ATOM   541  C CB  . ASP A 1 93  ? 5.67100  20.25500  151.73800 1.000 7.95000  ? 93  ASP A CB  1 
ATOM   542  C CG  . ASP A 1 93  ? 5.15900  19.89200  153.14400 1.000 9.05000  ? 93  ASP A CG  1 
ATOM   543  O OD1 . ASP A 1 93  ? 4.53600  18.82300  153.32800 1.000 10.37000 ? 93  ASP A OD1 1 
ATOM   544  O OD2 . ASP A 1 93  ? 5.37200  20.70400  154.07500 1.000 13.09000 ? 93  ASP A OD2 1 
ATOM   545  N N   . PRO A 1 94  ? 4.31600  17.21400  150.83900 1.000 7.09000  ? 94  PRO A N   1 
ATOM   546  C CA  . PRO A 1 94  ? 3.01900  16.64400  150.44300 1.000 6.93000  ? 94  PRO A CA  1 
ATOM   547  C C   . PRO A 1 94  ? 1.83200  17.33200  151.08600 1.000 11.65000 ? 94  PRO A C   1 
ATOM   548  O O   . PRO A 1 94  ? 0.70200  17.11300  150.63300 1.000 10.82000 ? 94  PRO A O   1 
ATOM   549  C CB  . PRO A 1 94  ? 3.12000  15.18700  150.90400 1.000 8.93000  ? 94  PRO A CB  1 
ATOM   550  C CG  . PRO A 1 94  ? 4.04200  15.27400  152.11200 1.000 8.38000  ? 94  PRO A CG  1 
ATOM   551  C CD  . PRO A 1 94  ? 5.07500  16.29700  151.71400 1.000 8.60000  ? 94  PRO A CD  1 
ATOM   552  N N   . ARG A 1 95  ? 2.04100  18.13400  152.12800 1.000 9.68000  ? 95  ARG A N   1 
ATOM   553  C CA  . ARG A 1 95  ? 0.95400  18.85000  152.78400 1.000 10.82000 ? 95  ARG A CA  1 
ATOM   554  C C   . ARG A 1 95  ? 0.77000  20.23900  152.18500 1.000 10.63000 ? 95  ARG A C   1 
ATOM   555  O O   . ARG A 1 95  ? 1.73500  20.90800  151.81200 1.000 10.43000 ? 95  ARG A O   1 
ATOM   556  C CB  . ARG A 1 95  ? 1.22600  18.99300  154.28300 1.000 7.79000  ? 95  ARG A CB  1 
ATOM   557  C CG  . ARG A 1 95  ? 1.15300  17.68800  155.02700 1.000 9.80000  ? 95  ARG A CG  1 
ATOM   558  C CD  . ARG A 1 95  ? 1.16400  17.93000  156.53200 1.000 12.45000 ? 95  ARG A CD  1 
ATOM   559  N NE  . ARG A 1 95  ? 1.53100  16.71700  157.25600 1.000 16.05000 ? 95  ARG A NE  1 
ATOM   560  C CZ  . ARG A 1 95  ? 1.61700  16.63300  158.57900 1.000 16.50000 ? 95  ARG A CZ  1 
ATOM   561  N NH1 . ARG A 1 95  ? 1.35600  17.69500  159.33200 1.000 18.44000 ? 95  ARG A NH1 1 
ATOM   562  N NH2 . ARG A 1 95  ? 1.97000  15.48500  159.14500 1.000 14.95000 ? 95  ARG A NH2 1 
ATOM   563  N N   . GLU A 1 96  ? -0.49000 20.68800  152.13200 1.000 10.34000 ? 96  GLU A N   1 
ATOM   564  C CA  . GLU A 1 96  ? -0.76900 22.04200  151.65900 1.000 10.61000 ? 96  GLU A CA  1 
ATOM   565  C C   . GLU A 1 96  ? -0.29400 23.10100  152.64200 1.000 13.30000 ? 96  GLU A C   1 
ATOM   566  O O   . GLU A 1 96  ? -0.04000 24.24500  152.24900 1.000 14.91000 ? 96  GLU A O   1 
ATOM   567  C CB  . GLU A 1 96  ? -2.26200 22.21800  151.42300 1.000 13.30000 ? 96  GLU A CB  1 
ATOM   568  C CG  . GLU A 1 96  ? -2.75000 21.57500  150.16300 1.000 14.59000 ? 96  GLU A CG  1 
ATOM   569  C CD  . GLU A 1 96  ? -4.05100 22.18300  149.70900 1.000 19.05000 ? 96  GLU A CD  1 
ATOM   570  O OE1 . GLU A 1 96  ? -4.53100 23.11800  150.39500 1.000 15.56000 ? 96  GLU A OE1 1 
ATOM   571  O OE2 . GLU A 1 96  ? -4.58700 21.72700  148.67800 1.000 21.36000 ? 96  GLU A OE2 1 
ATOM   572  N N   . SER A 1 97  ? -0.19700 22.75800  153.91900 1.000 12.73000 ? 97  SER A N   1 
ATOM   573  C CA  . SER A 1 97  ? 0.30200  23.70200  154.90000 1.000 13.60000 ? 97  SER A CA  1 
ATOM   574  C C   . SER A 1 97  ? 0.95300  22.92500  156.03000 1.000 13.15000 ? 97  SER A C   1 
ATOM   575  O O   . SER A 1 97  ? 0.54400  21.80800  156.35800 1.000 15.64000 ? 97  SER A O   1 
ATOM   576  C CB  . SER A 1 97  ? -0.81700 24.60800  155.43200 1.000 23.07000 ? 97  SER A CB  1 
ATOM   577  O OG  . SER A 1 97  ? -1.70100 23.88300  156.25300 1.000 28.30000 ? 97  SER A OG  1 
ATOM   578  N N   . ARG A 1 98  ? 1.98500  23.52400  156.60400 1.000 12.15000 ? 98  ARG A N   1 
ATOM   579  C CA  . ARG A 1 98  ? 2.73200  22.88800  157.68400 1.000 13.31000 ? 98  ARG A CA  1 
ATOM   580  C C   . ARG A 1 98  ? 3.36000  23.98500  158.52100 1.000 17.37000 ? 98  ARG A C   1 
ATOM   581  O O   . ARG A 1 98  ? 4.53500  24.32700  158.34200 1.000 16.89000 ? 98  ARG A O   1 
ATOM   582  C CB  . ARG A 1 98  ? 3.79000  21.92200  157.13700 1.000 17.35000 ? 98  ARG A CB  1 
ATOM   583  C CG  . ARG A 1 98  ? 4.30900  20.94900  158.19700 1.000 14.49000 ? 98  ARG A CG  1 
ATOM   584  C CD  . ARG A 1 98  ? 5.45500  20.10000  157.68300 1.000 12.03000 ? 98  ARG A CD  1 
ATOM   585  N NE  . ARG A 1 98  ? 5.09800  19.24100  156.55500 1.000 9.09000  ? 98  ARG A NE  1 
ATOM   586  C CZ  . ARG A 1 98  ? 4.80400  17.94100  156.64400 1.000 8.26000  ? 98  ARG A CZ  1 
ATOM   587  N NH1 . ARG A 1 98  ? 4.77300  17.32900  157.82800 1.000 10.64000 ? 98  ARG A NH1 1 
ATOM   588  N NH2 . ARG A 1 98  ? 4.52600  17.24900  155.54200 1.000 8.49000  ? 98  ARG A NH2 1 
ATOM   589  N N   . ALA A 1 99  ? 2.57400  24.56700  159.41900 1.000 14.96000 ? 99  ALA A N   1 
ATOM   590  C CA  . ALA A 1 99  ? 2.99500  25.76500  160.12100 1.000 17.75000 ? 99  ALA A CA  1 
ATOM   591  C C   . ALA A 1 99  ? 3.63400  25.48800  161.47900 1.000 20.36000 ? 99  ALA A C   1 
ATOM   592  O O   . ALA A 1 99  ? 4.33200  26.36900  162.00100 1.000 25.01000 ? 99  ALA A O   1 
ATOM   593  C CB  . ALA A 1 99  ? 1.80100  26.71400  160.29700 1.000 20.85000 ? 99  ALA A CB  1 
ATOM   594  N N   . GLY A 1 100 ? 3.42900  24.30400  162.05700 1.000 19.39000 ? 100 GLY A N   1 
ATOM   595  C CA  . GLY A 1 100 ? 3.94900  23.99300  163.37300 1.000 21.22000 ? 100 GLY A CA  1 
ATOM   596  C C   . GLY A 1 100 ? 5.35900  23.43200  163.33300 1.000 20.16000 ? 100 GLY A C   1 
ATOM   597  O O   . GLY A 1 100 ? 5.89500  23.13800  162.26000 1.000 16.15000 ? 100 GLY A O   1 
ATOM   598  N N   . PRO A 1 101 ? 5.98500  23.27000  164.50600 1.000 16.09000 ? 101 PRO A N   1 
ATOM   599  C CA  . PRO A 1 101 ? 7.36000  22.74700  164.54600 1.000 15.60000 ? 101 PRO A CA  1 
ATOM   600  C C   . PRO A 1 101 ? 7.45300  21.36800  163.90500 1.000 15.59000 ? 101 PRO A C   1 
ATOM   601  O O   . PRO A 1 101 ? 6.58600  20.51100  164.09800 1.000 13.30000 ? 101 PRO A O   1 
ATOM   602  C CB  . PRO A 1 101 ? 7.67400  22.68900  166.04800 1.000 16.07000 ? 101 PRO A CB  1 
ATOM   603  C CG  . PRO A 1 101 ? 6.71600  23.66100  166.67800 1.000 18.00000 ? 101 PRO A CG  1 
ATOM   604  C CD  . PRO A 1 101 ? 5.47100  23.58700  165.85000 1.000 18.92000 ? 101 PRO A CD  1 
ATOM   605  N N   . THR A 1 102 ? 8.52100  21.15500  163.13500 1.000 10.53000 ? 102 THR A N   1 
ATOM   606  C CA  . THR A 1 102 ? 8.65500  19.93000  162.35700 1.000 9.94000  ? 102 THR A CA  1 
ATOM   607  C C   . THR A 1 102 ? 10.12900 19.65800  162.10800 1.000 10.74000 ? 102 THR A C   1 
ATOM   608  O O   . THR A 1 102 ? 10.90800 20.60100  161.93400 1.000 8.86000  ? 102 THR A O   1 
ATOM   609  C CB  . THR A 1 102 ? 7.90700  20.03800  161.00900 1.000 12.25000 ? 102 THR A CB  1 
ATOM   610  O OG1 . THR A 1 102 ? 8.07100  18.82900  160.25800 1.000 11.97000 ? 102 THR A OG1 1 
ATOM   611  C CG2 . THR A 1 102 ? 8.42000  21.21500  160.17100 1.000 11.20000 ? 102 THR A CG2 1 
ATOM   612  N N   . PRO A 1 103 ? 10.54200 18.39100  162.06700 1.000 11.43000 ? 103 PRO A N   1 
ATOM   613  C CA  . PRO A 1 103 ? 11.83200 18.08500  161.44200 1.000 9.41000  ? 103 PRO A CA  1 
ATOM   614  C C   . PRO A 1 103 ? 11.76400 18.47800  159.97800 1.000 7.80000  ? 103 PRO A C   1 
ATOM   615  O O   . PRO A 1 103 ? 10.69900 18.44000  159.35500 1.000 10.06000 ? 103 PRO A O   1 
ATOM   616  C CB  . PRO A 1 103 ? 11.97700 16.56500  161.60300 1.000 9.56000  ? 103 PRO A CB  1 
ATOM   617  C CG  . PRO A 1 103 ? 10.80800 16.10500  162.40400 1.000 14.58000 ? 103 PRO A CG  1 
ATOM   618  C CD  . PRO A 1 103 ? 9.78200  17.18700  162.43100 1.000 11.72000 ? 103 PRO A CD  1 
ATOM   619  N N   . VAL A 1 104 ? 12.91000 18.86300  159.42400 1.000 5.72000  ? 104 VAL A N   1 
ATOM   620  C CA  . VAL A 1 104 ? 13.00900 19.22100  158.01200 1.000 6.10000  ? 104 VAL A CA  1 
ATOM   621  C C   . VAL A 1 104 ? 14.09000 18.35600  157.38900 1.000 5.53000  ? 104 VAL A C   1 
ATOM   622  O O   . VAL A 1 104 ? 15.22200 18.32500  157.88600 1.000 6.31000  ? 104 VAL A O   1 
ATOM   623  C CB  . VAL A 1 104 ? 13.33200 20.71400  157.81400 1.000 6.98000  ? 104 VAL A CB  1 
ATOM   624  C CG1 . VAL A 1 104 ? 13.44900 21.04800  156.31900 1.000 6.80000  ? 104 VAL A CG1 1 
ATOM   625  C CG2 . VAL A 1 104 ? 12.27300 21.57900  158.46900 1.000 7.16000  ? 104 VAL A CG2 1 
ATOM   626  N N   . ILE A 1 105 ? 13.74500 17.66500  156.30800 1.000 5.04000  ? 105 ILE A N   1 
ATOM   627  C CA  . ILE A 1 105 ? 14.71400 16.84200  155.59300 1.000 4.59000  ? 105 ILE A CA  1 
ATOM   628  C C   . ILE A 1 105 ? 15.55200 17.74400  154.70200 1.000 7.26000  ? 105 ILE A C   1 
ATOM   629  O O   . ILE A 1 105 ? 15.01300 18.58100  153.97600 1.000 5.46000  ? 105 ILE A O   1 
ATOM   630  C CB  . ILE A 1 105 ? 14.00700 15.76300  154.75600 1.000 5.53000  ? 105 ILE A CB  1 
ATOM   631  C CG1 . ILE A 1 105 ? 13.18100 14.83900  155.64000 1.000 6.28000  ? 105 ILE A CG1 1 
ATOM   632  C CG2 . ILE A 1 105 ? 15.02700 14.97100  153.94600 1.000 6.84000  ? 105 ILE A CG2 1 
ATOM   633  C CD1 . ILE A 1 105 ? 12.23900 13.94400  154.84800 1.000 6.91000  ? 105 ILE A CD1 1 
ATOM   634  N N   . THR A 1 106 ? 16.87500 17.59000  154.76500 1.000 5.43000  ? 106 THR A N   1 
ATOM   635  C CA  . THR A 1 106 ? 17.79300 18.30500  153.88800 1.000 4.48000  ? 106 THR A CA  1 
ATOM   636  C C   . THR A 1 106 ? 18.49000 17.26700  153.02600 1.000 6.93000  ? 106 THR A C   1 
ATOM   637  O O   . THR A 1 106 ? 19.13600 16.35200  153.55200 1.000 5.88000  ? 106 THR A O   1 
ATOM   638  C CB  . THR A 1 106 ? 18.79600 19.13700  154.69500 1.000 5.76000  ? 106 THR A CB  1 
ATOM   639  O OG1 . THR A 1 106 ? 18.06900 20.03000  155.55800 1.000 8.40000  ? 106 THR A OG1 1 
ATOM   640  C CG2 . THR A 1 106 ? 19.69900 19.95400  153.76400 1.000 7.45000  ? 106 THR A CG2 1 
ATOM   641  N N   . PHE A 1 107 ? 18.31500 17.37800  151.71500 1.000 4.64000  ? 107 PHE A N   1 
ATOM   642  C CA  . PHE A 1 107 ? 18.69300 16.32900  150.78100 1.000 5.45000  ? 107 PHE A CA  1 
ATOM   643  C C   . PHE A 1 107 ? 19.85300 16.79500  149.91400 1.000 5.77000  ? 107 PHE A C   1 
ATOM   644  O O   . PHE A 1 107 ? 19.80200 17.89000  149.34700 1.000 5.79000  ? 107 PHE A O   1 
ATOM   645  C CB  . PHE A 1 107 ? 17.50400 15.95100  149.89600 1.000 5.30000  ? 107 PHE A CB  1 
ATOM   646  C CG  . PHE A 1 107 ? 17.83100 14.91100  148.86700 1.000 7.20000  ? 107 PHE A CG  1 
ATOM   647  C CD1 . PHE A 1 107 ? 18.32200 15.27600  147.61300 1.000 8.14000  ? 107 PHE A CD1 1 
ATOM   648  C CD2 . PHE A 1 107 ? 17.64300 13.56700  149.14300 1.000 10.41000 ? 107 PHE A CD2 1 
ATOM   649  C CE1 . PHE A 1 107 ? 18.63100 14.30600  146.67200 1.000 8.54000  ? 107 PHE A CE1 1 
ATOM   650  C CE2 . PHE A 1 107 ? 17.94200 12.60000  148.19500 1.000 10.31000 ? 107 PHE A CE2 1 
ATOM   651  C CZ  . PHE A 1 107 ? 18.43200 12.97900  146.96000 1.000 9.76000  ? 107 PHE A CZ  1 
ATOM   652  N N   . PHE A 1 108 ? 20.87300 15.94300  149.77600 1.000 5.71000  ? 108 PHE A N   1 
ATOM   653  C CA  . PHE A 1 108 ? 22.05300 16.22400  148.96000 1.000 5.73000  ? 108 PHE A CA  1 
ATOM   654  C C   . PHE A 1 108 ? 22.16900 15.15800  147.87500 1.000 6.36000  ? 108 PHE A C   1 
ATOM   655  O O   . PHE A 1 108 ? 22.36800 13.97500  148.18000 1.000 5.29000  ? 108 PHE A O   1 
ATOM   656  C CB  . PHE A 1 108 ? 23.33000 16.24500  149.81700 1.000 6.40000  ? 108 PHE A CB  1 
ATOM   657  C CG  . PHE A 1 108 ? 23.20800 17.03200  151.09600 1.000 5.87000  ? 108 PHE A CG  1 
ATOM   658  C CD1 . PHE A 1 108 ? 23.00800 18.40700  151.07300 1.000 5.87000  ? 108 PHE A CD1 1 
ATOM   659  C CD2 . PHE A 1 108 ? 23.31500 16.39700  152.32900 1.000 6.02000  ? 108 PHE A CD2 1 
ATOM   660  C CE1 . PHE A 1 108 ? 22.91300 19.14200  152.25800 1.000 5.31000  ? 108 PHE A CE1 1 
ATOM   661  C CE2 . PHE A 1 108 ? 23.21600 17.12000  153.52000 1.000 7.83000  ? 108 PHE A CE2 1 
ATOM   662  C CZ  . PHE A 1 108 ? 23.01400 18.49400  153.48500 1.000 4.78000  ? 108 PHE A CZ  1 
ATOM   663  N N   . HIS A 1 109 ? 22.07500 15.57600  146.61100 1.000 6.19000  ? 109 HIS A N   1 
ATOM   664  C CA  . HIS A 1 109 ? 22.04100 14.62300  145.50900 1.000 5.48000  ? 109 HIS A CA  1 
ATOM   665  C C   . HIS A 1 109 ? 23.41800 14.00800  145.23800 1.000 6.32000  ? 109 HIS A C   1 
ATOM   666  O O   . HIS A 1 109 ? 24.46800 14.56400  145.58200 1.000 7.08000  ? 109 HIS A O   1 
ATOM   667  C CB  . HIS A 1 109 ? 21.52900 15.30000  144.23800 1.000 5.44000  ? 109 HIS A CB  1 
ATOM   668  C CG  . HIS A 1 109 ? 22.47200 16.32000  143.67600 1.000 5.97000  ? 109 HIS A CG  1 
ATOM   669  N ND1 . HIS A 1 109 ? 23.52800 15.98000  142.85400 1.000 5.40000  ? 109 HIS A ND1 1 
ATOM   670  C CD2 . HIS A 1 109 ? 22.51600 17.66800  143.81100 1.000 5.73000  ? 109 HIS A CD2 1 
ATOM   671  C CE1 . HIS A 1 109 ? 24.18400 17.07500  142.51300 1.000 6.27000  ? 109 HIS A CE1 1 
ATOM   672  N NE2 . HIS A 1 109 ? 23.58800 18.11300  143.07300 1.000 6.13000  ? 109 HIS A NE2 1 
ATOM   673  N N   . GLY A 1 110 ? 23.39100 12.84600  144.58400 1.000 7.20000  ? 110 GLY A N   1 
ATOM   674  C CA  . GLY A 1 110 ? 24.60000 12.17100  144.15800 1.000 7.05000  ? 110 GLY A CA  1 
ATOM   675  C C   . GLY A 1 110 ? 25.06200 12.67900  142.81300 1.000 6.86000  ? 110 GLY A C   1 
ATOM   676  O O   . GLY A 1 110 ? 24.44800 13.55300  142.20500 1.000 7.39000  ? 110 GLY A O   1 
ATOM   677  N N   . GLY A 1 111 ? 26.18500 12.12600  142.35700 1.000 5.18000  ? 111 GLY A N   1 
ATOM   678  C CA  . GLY A 1 111 ? 26.78600 12.57900  141.11200 1.000 7.07000  ? 111 GLY A CA  1 
ATOM   679  C C   . GLY A 1 111 ? 28.28000 12.83300  141.18800 1.000 5.41000  ? 111 GLY A C   1 
ATOM   680  O O   . GLY A 1 111 ? 28.83400 13.53500  140.34200 1.000 5.89000  ? 111 GLY A O   1 
ATOM   681  N N   . GLY A 1 112 ? 28.95200 12.26700  142.18200 1.000 5.25000  ? 112 GLY A N   1 
ATOM   682  C CA  . GLY A 1 112 ? 30.40000 12.41600  142.26500 1.000 6.35000  ? 112 GLY A CA  1 
ATOM   683  C C   . GLY A 1 112 ? 30.88700 13.80400  142.58500 1.000 7.71000  ? 112 GLY A C   1 
ATOM   684  O O   . GLY A 1 112 ? 32.09500 14.05300  142.49900 1.000 7.95000  ? 112 GLY A O   1 
ATOM   685  N N   . PHE A 1 113 ? 29.98100 14.70400  142.97000 1.000 6.38000  ? 113 PHE A N   1 
ATOM   686  C CA  . PHE A 1 113 ? 30.19200 16.14000  143.11800 1.000 7.18000  ? 113 PHE A CA  1 
ATOM   687  C C   . PHE A 1 113 ? 30.41100 16.82800  141.77700 1.000 8.27000  ? 113 PHE A C   1 
ATOM   688  O O   . PHE A 1 113 ? 30.77700 18.00700  141.75500 1.000 7.93000  ? 113 PHE A O   1 
ATOM   689  C CB  . PHE A 1 113 ? 31.35200 16.46600  144.07000 1.000 6.51000  ? 113 PHE A CB  1 
ATOM   690  C CG  . PHE A 1 113 ? 31.09900 16.04700  145.49800 1.000 5.89000  ? 113 PHE A CG  1 
ATOM   691  C CD1 . PHE A 1 113 ? 30.06900 16.62000  146.22700 1.000 8.38000  ? 113 PHE A CD1 1 
ATOM   692  C CD2 . PHE A 1 113 ? 31.88400 15.08000  146.09800 1.000 7.12000  ? 113 PHE A CD2 1 
ATOM   693  C CE1 . PHE A 1 113 ? 29.82600 16.24100  147.54900 1.000 9.30000  ? 113 PHE A CE1 1 
ATOM   694  C CE2 . PHE A 1 113 ? 31.65400 14.69600  147.42900 1.000 6.35000  ? 113 PHE A CE2 1 
ATOM   695  C CZ  . PHE A 1 113 ? 30.62000 15.28000  148.14500 1.000 7.45000  ? 113 PHE A CZ  1 
ATOM   696  N N   . VAL A 1 114 ? 30.16400 16.13200  140.66200 1.000 6.70000  ? 114 VAL A N   1 
ATOM   697  C CA  . VAL A 1 114 ? 30.36900 16.66300  139.31700 1.000 6.19000  ? 114 VAL A CA  1 
ATOM   698  C C   . VAL A 1 114 ? 29.05200 16.80100  138.56200 1.000 6.01000  ? 114 VAL A C   1 
ATOM   699  O O   . VAL A 1 114 ? 28.80500 17.81200  137.90500 1.000 5.64000  ? 114 VAL A O   1 
ATOM   700  C CB  . VAL A 1 114 ? 31.36000 15.78900  138.52100 1.000 6.07000  ? 114 VAL A CB  1 
ATOM   701  C CG1 . VAL A 1 114 ? 31.47500 16.29500  137.08300 1.000 8.42000  ? 114 VAL A CG1 1 
ATOM   702  C CG2 . VAL A 1 114 ? 32.72200 15.79000  139.19500 1.000 6.78000  ? 114 VAL A CG2 1 
ATOM   703  N N   . ILE A 1 115 ? 28.20800 15.77200  138.61500 1.000 5.50000  ? 115 ILE A N   1 
ATOM   704  C CA  . ILE A 1 115 ? 26.94200 15.79500  137.89300 1.000 4.88000  ? 115 ILE A CA  1 
ATOM   705  C C   . ILE A 1 115 ? 25.80400 15.74400  138.90400 1.000 5.35000  ? 115 ILE A C   1 
ATOM   706  O O   . ILE A 1 115 ? 26.03700 15.68200  140.11700 1.000 7.44000  ? 115 ILE A O   1 
ATOM   707  C CB  . ILE A 1 115 ? 26.85100 14.63800  136.87700 1.000 4.38000  ? 115 ILE A CB  1 
ATOM   708  C CG1 . ILE A 1 115 ? 26.89800 13.27600  137.57800 1.000 6.81000  ? 115 ILE A CG1 1 
ATOM   709  C CG2 . ILE A 1 115 ? 27.98800 14.73200  135.86700 1.000 7.20000  ? 115 ILE A CG2 1 
ATOM   710  C CD1 . ILE A 1 115 ? 26.91600 12.08800  136.58800 1.000 8.98000  ? 115 ILE A CD1 1 
ATOM   711  N N   . GLY A 1 116 ? 24.57500 15.80200  138.41500 1.000 6.87000  ? 116 GLY A N   1 
ATOM   712  C CA  . GLY A 1 116 ? 23.41600 15.85400  139.29500 1.000 6.21000  ? 116 GLY A CA  1 
ATOM   713  C C   . GLY A 1 116 ? 22.99700 17.27600  139.60500 1.000 6.98000  ? 116 GLY A C   1 
ATOM   714  O O   . GLY A 1 116 ? 23.79400 18.21400  139.59600 1.000 6.95000  ? 116 GLY A O   1 
ATOM   715  N N   . ASP A 1 117 ? 21.71000 17.43900  139.89000 1.000 5.58000  ? 117 ASP A N   1 
ATOM   716  C CA  . ASP A 1 117 ? 21.16600 18.75400  140.20400 1.000 6.66000  ? 117 ASP A CA  1 
ATOM   717  C C   . ASP A 1 117 ? 19.78200 18.59300  140.81600 1.000 6.44000  ? 117 ASP A C   1 
ATOM   718  O O   . ASP A 1 117 ? 19.42700 17.50500  141.28000 1.000 7.11000  ? 117 ASP A O   1 
ATOM   719  C CB  . ASP A 1 117 ? 21.11800 19.62600  138.93900 1.000 8.76000  ? 117 ASP A CB  1 
ATOM   720  C CG  . ASP A 1 117 ? 20.47800 18.89900  137.75900 1.000 11.61000 ? 117 ASP A CG  1 
ATOM   721  O OD1 . ASP A 1 117 ? 19.37600 18.35700  137.93900 1.000 9.41000  ? 117 ASP A OD1 1 
ATOM   722  O OD2 . ASP A 1 117 ? 21.07700 18.85000  136.65500 1.000 17.60000 ? 117 ASP A OD2 1 
ATOM   723  N N   . LEU A 1 118 ? 18.98600 19.66000  140.83200 1.000 6.90000  ? 118 LEU A N   1 
ATOM   724  C CA  . LEU A 1 118 ? 17.66200 19.53600  141.42500 1.000 6.33000  ? 118 LEU A CA  1 
ATOM   725  C C   . LEU A 1 118 ? 16.72800 18.69200  140.56800 1.000 8.83000  ? 118 LEU A C   1 
ATOM   726  O O   . LEU A 1 118 ? 15.76000 18.12600  141.09300 1.000 10.57000 ? 118 LEU A O   1 
ATOM   727  C CB  . LEU A 1 118 ? 17.05500 20.92000  141.65300 1.000 7.03000  ? 118 LEU A CB  1 
ATOM   728  C CG  . LEU A 1 118 ? 17.86100 21.84900  142.56500 1.000 6.43000  ? 118 LEU A CG  1 
ATOM   729  C CD1 . LEU A 1 118 ? 17.22200 23.25300  142.57400 1.000 9.97000  ? 118 LEU A CD1 1 
ATOM   730  C CD2 . LEU A 1 118 ? 17.92600 21.27900  143.99200 1.000 7.98000  ? 118 LEU A CD2 1 
ATOM   731  N N   . ASP A 1 119 ? 17.00400 18.57200  139.27200 1.000 7.62000  ? 119 ASP A N   1 
ATOM   732  C CA  . ASP A 1 119 ? 16.11600 17.81100  138.40400 1.000 8.54000  ? 119 ASP A CA  1 
ATOM   733  C C   . ASP A 1 119 ? 16.46600 16.32800  138.33600 1.000 8.02000  ? 119 ASP A C   1 
ATOM   734  O O   . ASP A 1 119 ? 15.55800 15.49600  138.21100 1.000 6.81000  ? 119 ASP A O   1 
ATOM   735  C CB  . ASP A 1 119 ? 16.11600 18.42500  137.00200 1.000 10.59000 ? 119 ASP A CB  1 
ATOM   736  C CG  . ASP A 1 119 ? 15.52500 19.83200  136.98800 1.000 17.89000 ? 119 ASP A CG  1 
ATOM   737  O OD1 . ASP A 1 119 ? 14.58800 20.09300  137.77200 1.000 14.64000 ? 119 ASP A OD1 1 
ATOM   738  O OD2 . ASP A 1 119 ? 16.00400 20.67600  136.20100 1.000 17.79000 ? 119 ASP A OD2 1 
ATOM   739  N N   . THR A 1 120 ? 17.75500 15.96900  138.42200 1.000 6.88000  ? 120 THR A N   1 
ATOM   740  C CA  . THR A 1 120 ? 18.13700 14.56100  138.30800 1.000 5.59000  ? 120 THR A CA  1 
ATOM   741  C C   . THR A 1 120 ? 17.53600 13.71900  139.42700 1.000 7.48000  ? 120 THR A C   1 
ATOM   742  O O   . THR A 1 120 ? 17.21600 12.53800  139.22200 1.000 8.37000  ? 120 THR A O   1 
ATOM   743  C CB  . THR A 1 120 ? 19.66000 14.40500  138.32300 1.000 7.16000  ? 120 THR A CB  1 
ATOM   744  O OG1 . THR A 1 120 ? 20.19700 14.96000  139.53300 1.000 7.08000  ? 120 THR A OG1 1 
ATOM   745  C CG2 . THR A 1 120 ? 20.29900 15.10400  137.11300 1.000 7.80000  ? 120 THR A CG2 1 
ATOM   746  N N   . HIS A 1 121 ? 17.39500 14.29900  140.61900 1.000 5.35000  ? 121 HIS A N   1 
ATOM   747  C CA  . HIS A 1 121 ? 16.89500 13.57000  141.77600 1.000 6.62000  ? 121 HIS A CA  1 
ATOM   748  C C   . HIS A 1 121 ? 15.49500 14.02500  142.16700 1.000 8.63000  ? 121 HIS A C   1 
ATOM   749  O O   . HIS A 1 121 ? 15.01500 13.69600  143.25900 1.000 6.94000  ? 121 HIS A O   1 
ATOM   750  C CB  . HIS A 1 121 ? 17.87700 13.70600  142.93900 1.000 6.51000  ? 121 HIS A CB  1 
ATOM   751  C CG  . HIS A 1 121 ? 19.14100 12.93000  142.73300 1.000 4.87000  ? 121 HIS A CG  1 
ATOM   752  N ND1 . HIS A 1 121 ? 20.00400 13.17800  141.68300 1.000 5.51000  ? 121 HIS A ND1 1 
ATOM   753  C CD2 . HIS A 1 121 ? 19.67000 11.88800  143.41800 1.000 7.18000  ? 121 HIS A CD2 1 
ATOM   754  C CE1 . HIS A 1 121 ? 21.02200 12.33800  141.74800 1.000 5.98000  ? 121 HIS A CE1 1 
ATOM   755  N NE2 . HIS A 1 121 ? 20.84400 11.54200  142.78900 1.000 5.86000  ? 121 HIS A NE2 1 
ATOM   756  N N   . HIS A 1 122 ? 14.82300 14.72900  141.25500 1.000 6.10000  ? 122 HIS A N   1 
ATOM   757  C CA  . HIS A 1 122 ? 13.51800 15.31800  141.53200 1.000 6.88000  ? 122 HIS A CA  1 
ATOM   758  C C   . HIS A 1 122 ? 12.48500 14.26100  141.91700 1.000 7.71000  ? 122 HIS A C   1 
ATOM   759  O O   . HIS A 1 122 ? 11.75200 14.42800  142.89800 1.000 7.08000  ? 122 HIS A O   1 
ATOM   760  C CB  . HIS A 1 122 ? 13.07000 16.11400  140.30300 1.000 7.20000  ? 122 HIS A CB  1 
ATOM   761  C CG  . HIS A 1 122 ? 11.73000 16.76700  140.45200 1.000 9.45000  ? 122 HIS A CG  1 
ATOM   762  N ND1 . HIS A 1 122 ? 11.51700 17.86300  141.26000 1.000 13.81000 ? 122 HIS A ND1 1 
ATOM   763  C CD2 . HIS A 1 122 ? 10.53600 16.48200  139.88100 1.000 12.60000 ? 122 HIS A CD2 1 
ATOM   764  C CE1 . HIS A 1 122 ? 10.24800 18.22600  141.18000 1.000 14.29000 ? 122 HIS A CE1 1 
ATOM   765  N NE2 . HIS A 1 122 ? 9.63100  17.40100  140.35400 1.000 14.35000 ? 122 HIS A NE2 1 
ATOM   766  N N   . ALA A 1 123 ? 12.39500 13.17300  141.14500 1.000 7.72000  ? 123 ALA A N   1 
ATOM   767  C CA  . ALA A 1 123 ? 11.38600 12.15600  141.43600 1.000 8.20000  ? 123 ALA A CA  1 
ATOM   768  C C   . ALA A 1 123 ? 11.62900 11.51300  142.79100 1.000 8.76000  ? 123 ALA A C   1 
ATOM   769  O O   . ALA A 1 123 ? 10.68800 11.32100  143.56700 1.000 7.50000  ? 123 ALA A O   1 
ATOM   770  C CB  . ALA A 1 123 ? 11.36400 11.08300  140.34700 1.000 8.54000  ? 123 ALA A CB  1 
ATOM   771  N N   . LEU A 1 124 ? 12.88600 11.16900  143.08900 1.000 5.74000  ? 124 LEU A N   1 
ATOM   772  C CA  . LEU A 1 124 ? 13.19800 10.58800  144.39500 1.000 7.52000  ? 124 LEU A CA  1 
ATOM   773  C C   . LEU A 1 124 ? 12.83500 11.54000  145.52800 1.000 7.37000  ? 124 LEU A C   1 
ATOM   774  O O   . LEU A 1 124 ? 12.33100 11.10900  146.57300 1.000 5.39000  ? 124 LEU A O   1 
ATOM   775  C CB  . LEU A 1 124 ? 14.68100 10.21200  144.45400 1.000 8.60000  ? 124 LEU A CB  1 
ATOM   776  C CG  . LEU A 1 124 ? 15.17800 9.67900   145.80300 1.000 8.37000  ? 124 LEU A CG  1 
ATOM   777  C CD1 . LEU A 1 124 ? 14.44300 8.41100   146.19000 1.000 5.94000  ? 124 LEU A CD1 1 
ATOM   778  C CD2 . LEU A 1 124 ? 16.68100 9.45000   145.72100 1.000 9.07000  ? 124 LEU A CD2 1 
ATOM   779  N N   . CYS A 1 125 ? 13.08200 12.84200  145.34400 1.000 6.70000  ? 125 CYS A N   1 
ATOM   780  C CA  . CYS A 1 125 ? 12.73300 13.80100  146.39100 1.000 6.73000  ? 125 CYS A CA  1 
ATOM   781  C C   . CYS A 1 125 ? 11.22500 13.84100  146.63800 1.000 6.62000  ? 125 CYS A C   1 
ATOM   782  O O   . CYS A 1 125 ? 10.78600 13.89200  147.79600 1.000 7.20000  ? 125 CYS A O   1 
ATOM   783  C CB  . CYS A 1 125 ? 13.24500 15.19600  146.04700 1.000 6.57000  ? 125 CYS A CB  1 
ATOM   784  S SG  . CYS A 1 125 ? 15.04100 15.39500  146.31900 1.000 8.20000  ? 125 CYS A SG  1 
ATOM   785  N N   . THR A 1 126 ? 10.40800 13.85700  145.57300 1.000 6.13000  ? 126 THR A N   1 
ATOM   786  C CA  . THR A 1 126 ? 8.96300  13.82300  145.80500 1.000 7.51000  ? 126 THR A CA  1 
ATOM   787  C C   . THR A 1 126 ? 8.55200  12.54100  146.51000 1.000 7.80000  ? 126 THR A C   1 
ATOM   788  O O   . THR A 1 126 ? 7.60400  12.55700  147.30400 1.000 7.12000  ? 126 THR A O   1 
ATOM   789  C CB  . THR A 1 126 ? 8.15800  13.97100  144.50400 1.000 7.35000  ? 126 THR A CB  1 
ATOM   790  O OG1 . THR A 1 126 ? 8.26400  12.78200  143.70600 1.000 9.68000  ? 126 THR A OG1 1 
ATOM   791  C CG2 . THR A 1 126 ? 8.58500  15.20000  143.71300 1.000 5.59000  ? 126 THR A CG2 1 
ATOM   792  N N   . GLU A 1 127 ? 9.26300  11.43500  146.25300 1.000 6.90000  ? 127 GLU A N   1 
ATOM   793  C CA  . GLU A 1 127 ? 8.93600  10.15600  146.87900 1.000 7.30000  ? 127 GLU A CA  1 
ATOM   794  C C   . GLU A 1 127 ? 9.27100  10.16000  148.36700 1.000 5.51000  ? 127 GLU A C   1 
ATOM   795  O O   . GLU A 1 127 ? 8.46100  9.72700   149.19500 1.000 8.66000  ? 127 GLU A O   1 
ATOM   796  C CB  . GLU A 1 127 ? 9.68800  9.02300   146.18100 1.000 7.17000  ? 127 GLU A CB  1 
ATOM   797  C CG  . GLU A 1 127 ? 9.15600  7.63000   146.51700 1.000 8.16000  ? 127 GLU A CG  1 
ATOM   798  C CD  . GLU A 1 127 ? 7.83400  7.32700   145.81500 1.000 16.47000 ? 127 GLU A CD  1 
ATOM   799  O OE1 . GLU A 1 127 ? 7.16600  6.34600   146.20400 1.000 15.03000 ? 127 GLU A OE1 1 
ATOM   800  O OE2 . GLU A 1 127 ? 7.45800  8.06400   144.87200 1.000 17.10000 ? 127 GLU A OE2 1 
ATOM   801  N N   . ILE A 1 128 ? 10.47200 10.62100  148.72200 1.000 5.29000  ? 128 ILE A N   1 
ATOM   802  C CA  . ILE A 1 128 ? 10.85000 10.65700  150.12900 1.000 5.06000  ? 128 ILE A CA  1 
ATOM   803  C C   . ILE A 1 128 ? 9.92500  11.58700  150.89900 1.000 7.05000  ? 128 ILE A C   1 
ATOM   804  O O   . ILE A 1 128 ? 9.44800  11.24800  151.98900 1.000 6.94000  ? 128 ILE A O   1 
ATOM   805  C CB  . ILE A 1 128 ? 12.32400 11.07500  150.28800 1.000 4.85000  ? 128 ILE A CB  1 
ATOM   806  C CG1 . ILE A 1 128 ? 13.25100 10.02200  149.67200 1.000 6.94000  ? 128 ILE A CG1 1 
ATOM   807  C CG2 . ILE A 1 128 ? 12.64100 11.29100  151.77400 1.000 6.36000  ? 128 ILE A CG2 1 
ATOM   808  C CD1 . ILE A 1 128 ? 14.69800 10.50300  149.48600 1.000 6.62000  ? 128 ILE A CD1 1 
ATOM   809  N N   . ALA A 1 129 ? 9.64000  12.76800  150.33500 1.000 6.20000  ? 129 ALA A N   1 
ATOM   810  C CA  . ALA A 1 129 ? 8.78600  13.73400  151.02100 1.000 8.08000  ? 129 ALA A CA  1 
ATOM   811  C C   . ALA A 1 129 ? 7.39600  13.15500  151.26000 1.000 7.29000  ? 129 ALA A C   1 
ATOM   812  O O   . ALA A 1 129 ? 6.83600  13.27200  152.35700 1.000 6.44000  ? 129 ALA A O   1 
ATOM   813  C CB  . ALA A 1 129 ? 8.70000  15.03000  150.20700 1.000 6.99000  ? 129 ALA A CB  1 
ATOM   814  N N   . ALA A 1 130 ? 6.83900  12.49800  150.24300 1.000 7.22000  ? 130 ALA A N   1 
ATOM   815  C CA  . ALA A 1 130 ? 5.50000  11.93300  150.35900 1.000 7.50000  ? 130 ALA A CA  1 
ATOM   816  C C   . ALA A 1 130 ? 5.45800  10.77900  151.35300 1.000 8.21000  ? 130 ALA A C   1 
ATOM   817  O O   . ALA A 1 130 ? 4.52100  10.68300  152.16000 1.000 8.08000  ? 130 ALA A O   1 
ATOM   818  C CB  . ALA A 1 130 ? 5.01600  11.47200  148.98500 1.000 9.29000  ? 130 ALA A CB  1 
ATOM   819  N N   . LEU A 1 131 ? 6.45000  9.88100   151.30100 1.000 6.72000  ? 131 LEU A N   1 
ATOM   820  C CA  . LEU A 1 131 ? 6.42300  8.69200   152.14500 1.000 6.44000  ? 131 LEU A CA  1 
ATOM   821  C C   . LEU A 1 131 ? 6.78100  9.01500   153.59100 1.000 9.54000  ? 131 LEU A C   1 
ATOM   822  O O   . LEU A 1 131 ? 6.31900  8.32800   154.51100 1.000 8.95000  ? 131 LEU A O   1 
ATOM   823  C CB  . LEU A 1 131 ? 7.37900  7.63300   151.59400 1.000 6.22000  ? 131 LEU A CB  1 
ATOM   824  C CG  . LEU A 1 131 ? 6.98400  7.05200   150.22700 1.000 8.16000  ? 131 LEU A CG  1 
ATOM   825  C CD1 . LEU A 1 131 ? 7.97400  5.96100   149.80500 1.000 10.77000 ? 131 LEU A CD1 1 
ATOM   826  C CD2 . LEU A 1 131 ? 5.55700  6.52300   150.26400 1.000 10.47000 ? 131 LEU A CD2 1 
ATOM   827  N N   . MET A 1 132 ? 7.59400  10.04500  153.81500 1.000 7.25000  ? 132 MET A N   1 
ATOM   828  C CA  . MET A 1 132 ? 7.87400  10.48600  155.17700 1.000 7.47000  ? 132 MET A CA  1 
ATOM   829  C C   . MET A 1 132 ? 6.79700  11.41000  155.72800 1.000 8.92000  ? 132 MET A C   1 
ATOM   830  O O   . MET A 1 132 ? 6.71800  11.58200  156.94700 1.000 8.06000  ? 132 MET A O   1 
ATOM   831  C CB  . MET A 1 132 ? 9.22600  11.21600  155.25700 1.000 5.46000  ? 132 MET A CB  1 
ATOM   832  C CG  . MET A 1 132 ? 10.45000 10.32100  155.07400 1.000 6.03000  ? 132 MET A CG  1 
ATOM   833  S SD  . MET A 1 132 ? 10.54500 9.02600   156.33700 1.000 8.05000  ? 132 MET A SD  1 
ATOM   834  C CE  . MET A 1 132 ? 10.68000 10.00900  157.83400 1.000 7.74000  ? 132 MET A CE  1 
ATOM   835  N N   . ASP A 1 133 ? 5.97700  12.00600  154.86900 1.000 6.45000  ? 133 ASP A N   1 
ATOM   836  C CA  . ASP A 1 133 ? 5.06700  13.08200  155.27800 1.000 8.58000  ? 133 ASP A CA  1 
ATOM   837  C C   . ASP A 1 133 ? 5.82600  14.18000  156.03100 1.000 9.33000  ? 133 ASP A C   1 
ATOM   838  O O   . ASP A 1 133 ? 5.45100  14.59900  157.12900 1.000 8.23000  ? 133 ASP A O   1 
ATOM   839  C CB  . ASP A 1 133 ? 3.90100  12.53400  156.11300 1.000 8.85000  ? 133 ASP A CB  1 
ATOM   840  C CG  . ASP A 1 133 ? 2.82900  13.58500  156.38900 1.000 14.41000 ? 133 ASP A CG  1 
ATOM   841  O OD1 . ASP A 1 133 ? 2.81200  14.62300  155.69300 1.000 10.03000 ? 133 ASP A OD1 1 
ATOM   842  O OD2 . ASP A 1 133 ? 2.00400  13.37000  157.30900 1.000 14.81000 ? 133 ASP A OD2 1 
ATOM   843  N N   . LEU A 1 134 ? 6.91700  14.64600  155.42300 1.000 6.26000  ? 134 LEU A N   1 
ATOM   844  C CA  . LEU A 1 134 ? 7.76900  15.68400  155.98600 1.000 6.87000  ? 134 LEU A CA  1 
ATOM   845  C C   . LEU A 1 134 ? 8.18700  16.62900  154.87300 1.000 6.29000  ? 134 LEU A C   1 
ATOM   846  O O   . LEU A 1 134 ? 8.23300  16.22400  153.70500 1.000 7.94000  ? 134 LEU A O   1 
ATOM   847  C CB  . LEU A 1 134 ? 9.03200  15.09500  156.63500 1.000 7.95000  ? 134 LEU A CB  1 
ATOM   848  C CG  . LEU A 1 134 ? 8.83200  14.42100  157.98600 1.000 7.48000  ? 134 LEU A CG  1 
ATOM   849  C CD1 . LEU A 1 134 ? 10.16900 13.82700  158.44300 1.000 7.34000  ? 134 LEU A CD1 1 
ATOM   850  C CD2 . LEU A 1 134 ? 8.32300  15.44200  159.00400 1.000 8.21000  ? 134 LEU A CD2 1 
ATOM   851  N N   . PRO A 1 135 ? 8.51600  17.88000  155.20300 1.000 5.02000  ? 135 PRO A N   1 
ATOM   852  C CA  . PRO A 1 135 ? 9.09200  18.76900  154.19500 1.000 6.63000  ? 135 PRO A CA  1 
ATOM   853  C C   . PRO A 1 135 ? 10.53400 18.38300  153.91200 1.000 7.24000  ? 135 PRO A C   1 
ATOM   854  O O   . PRO A 1 135 ? 11.26400 17.91500  154.79300 1.000 8.43000  ? 135 PRO A O   1 
ATOM   855  C CB  . PRO A 1 135 ? 9.00100  20.15100  154.84800 1.000 8.04000  ? 135 PRO A CB  1 
ATOM   856  C CG  . PRO A 1 135 ? 9.14500  19.86100  156.32100 1.000 8.05000  ? 135 PRO A CG  1 
ATOM   857  C CD  . PRO A 1 135 ? 8.47800  18.51100  156.53700 1.000 7.58000  ? 135 PRO A CD  1 
ATOM   858  N N   . LEU A 1 136 ? 10.93300 18.57500  152.65800 1.000 6.95000  ? 136 LEU A N   1 
ATOM   859  C CA  . LEU A 1 136 ? 12.26400 18.20500  152.19900 1.000 5.63000  ? 136 LEU A CA  1 
ATOM   860  C C   . LEU A 1 136 ? 12.81700 19.35000  151.36600 1.000 5.42000  ? 136 LEU A C   1 
ATOM   861  O O   . LEU A 1 136 ? 12.12600 19.85900  150.47800 1.000 5.32000  ? 136 LEU A O   1 
ATOM   862  C CB  . LEU A 1 136 ? 12.20800 16.90000  151.38300 1.000 5.04000  ? 136 LEU A CB  1 
ATOM   863  C CG  . LEU A 1 136 ? 13.49700 16.29500  150.81400 1.000 6.05000  ? 136 LEU A CG  1 
ATOM   864  C CD1 . LEU A 1 136 ? 13.29200 14.79000  150.61500 1.000 5.60000  ? 136 LEU A CD1 1 
ATOM   865  C CD2 . LEU A 1 136 ? 13.88600 16.94700  149.47000 1.000 5.44000  ? 136 LEU A CD2 1 
ATOM   866  N N   . VAL A 1 137 ? 14.05800 19.75200  151.64600 1.000 4.20000  ? 137 VAL A N   1 
ATOM   867  C CA  . VAL A 1 137 ? 14.74500 20.78000  150.87000 1.000 3.92000  ? 137 VAL A CA  1 
ATOM   868  C C   . VAL A 1 137 ? 15.94600 20.14100  150.18500 1.000 5.33000  ? 137 VAL A C   1 
ATOM   869  O O   . VAL A 1 137 ? 16.84900 19.63400  150.85900 1.000 5.70000  ? 137 VAL A O   1 
ATOM   870  C CB  . VAL A 1 137 ? 15.19300 21.95500  151.75000 1.000 5.72000  ? 137 VAL A CB  1 
ATOM   871  C CG1 . VAL A 1 137 ? 15.85200 23.02500  150.88000 1.000 5.11000  ? 137 VAL A CG1 1 
ATOM   872  C CG2 . VAL A 1 137 ? 14.00600 22.52200  152.52800 1.000 7.30000  ? 137 VAL A CG2 1 
ATOM   873  N N   . ALA A 1 138 ? 15.95500 20.17200  148.85200 1.000 5.24000  ? 138 ALA A N   1 
ATOM   874  C CA  . ALA A 1 138 ? 17.08700 19.69600  148.06000 1.000 6.47000  ? 138 ALA A CA  1 
ATOM   875  C C   . ALA A 1 138 ? 18.03600 20.85300  147.76100 1.000 7.17000  ? 138 ALA A C   1 
ATOM   876  O O   . ALA A 1 138 ? 17.59900 21.97900  147.50800 1.000 7.17000  ? 138 ALA A O   1 
ATOM   877  C CB  . ALA A 1 138 ? 16.59200 19.06100  146.75700 1.000 6.37000  ? 138 ALA A CB  1 
ATOM   878  N N   . VAL A 1 139 ? 19.34000 20.56200  147.75900 1.000 5.77000  ? 139 VAL A N   1 
ATOM   879  C CA  . VAL A 1 139 ? 20.38900 21.58000  147.67700 1.000 6.43000  ? 139 VAL A CA  1 
ATOM   880  C C   . VAL A 1 139 ? 21.14100 21.43700  146.35700 1.000 6.40000  ? 139 VAL A C   1 
ATOM   881  O O   . VAL A 1 139 ? 21.67300 20.36500  146.05300 1.000 8.01000  ? 139 VAL A O   1 
ATOM   882  C CB  . VAL A 1 139 ? 21.35500 21.46400  148.87200 1.000 5.99000  ? 139 VAL A CB  1 
ATOM   883  C CG1 . VAL A 1 139 ? 22.42700 22.56500  148.82100 1.000 7.76000  ? 139 VAL A CG1 1 
ATOM   884  C CG2 . VAL A 1 139 ? 20.57900 21.51700  150.18100 1.000 7.10000  ? 139 VAL A CG2 1 
ATOM   885  N N   . HIS A 1 140 ? 21.20600 22.52500  145.58500 1.000 5.33000  ? 140 HIS A N   1 
ATOM   886  C CA  . HIS A 1 140 ? 21.97200 22.56100  144.33400 1.000 6.71000  ? 140 HIS A CA  1 
ATOM   887  C C   . HIS A 1 140 ? 23.36600 23.12600  144.62400 1.000 7.62000  ? 140 HIS A C   1 
ATOM   888  O O   . HIS A 1 140 ? 23.68200 24.27600  144.32400 1.000 11.08000 ? 140 HIS A O   1 
ATOM   889  C CB  . HIS A 1 140 ? 21.23100 23.39900  143.29700 1.000 8.17000  ? 140 HIS A CB  1 
ATOM   890  C CG  . HIS A 1 140 ? 21.78900 23.30200  141.91100 1.000 11.47000 ? 140 HIS A CG  1 
ATOM   891  N ND1 . HIS A 1 140 ? 22.70200 22.33900  141.53500 1.000 10.77000 ? 140 HIS A ND1 1 
ATOM   892  C CD2 . HIS A 1 140 ? 21.55700 24.05100  140.80700 1.000 20.33000 ? 140 HIS A CD2 1 
ATOM   893  C CE1 . HIS A 1 140 ? 23.01200 22.50300  140.26000 1.000 12.91000 ? 140 HIS A CE1 1 
ATOM   894  N NE2 . HIS A 1 140 ? 22.32900 23.53400  139.79400 1.000 16.24000 ? 140 HIS A NE2 1 
ATOM   895  N N   . TYR A 1 141 ? 24.19500 22.29900  145.25800 1.000 6.89000  ? 141 TYR A N   1 
ATOM   896  C CA  . TYR A 1 141 ? 25.50100 22.75900  145.71200 1.000 6.83000  ? 141 TYR A CA  1 
ATOM   897  C C   . TYR A 1 141 ? 26.46600 22.95200  144.54300 1.000 7.11000  ? 141 TYR A C   1 
ATOM   898  O O   . TYR A 1 141 ? 26.30700 22.37400  143.46700 1.000 7.16000  ? 141 TYR A O   1 
ATOM   899  C CB  . TYR A 1 141 ? 26.10600 21.76400  146.70500 1.000 6.16000  ? 141 TYR A CB  1 
ATOM   900  C CG  . TYR A 1 141 ? 26.12600 20.32900  146.21200 1.000 6.70000  ? 141 TYR A CG  1 
ATOM   901  C CD1 . TYR A 1 141 ? 27.10500 19.88800  145.32200 1.000 6.89000  ? 141 TYR A CD1 1 
ATOM   902  C CD2 . TYR A 1 141 ? 25.18500 19.41500  146.66200 1.000 5.65000  ? 141 TYR A CD2 1 
ATOM   903  C CE1 . TYR A 1 141 ? 27.12700 18.57100  144.87500 1.000 7.46000  ? 141 TYR A CE1 1 
ATOM   904  C CE2 . TYR A 1 141 ? 25.19100 18.10200  146.23100 1.000 7.24000  ? 141 TYR A CE2 1 
ATOM   905  C CZ  . TYR A 1 141 ? 26.17100 17.68600  145.34100 1.000 7.16000  ? 141 TYR A CZ  1 
ATOM   906  O OH  . TYR A 1 141 ? 26.17800 16.39300  144.92600 1.000 7.04000  ? 141 TYR A OH  1 
ATOM   907  N N   . ALA A 1 142 ? 27.49300 23.77400  144.77800 1.000 8.09000  ? 142 ALA A N   1 
ATOM   908  C CA  . ALA A 1 142 ? 28.51300 24.02700  143.76100 1.000 8.03000  ? 142 ALA A CA  1 
ATOM   909  C C   . ALA A 1 142 ? 29.21500 22.73300  143.35600 1.000 7.45000  ? 142 ALA A C   1 
ATOM   910  O O   . ALA A 1 142 ? 29.65300 21.95500  144.21100 1.000 7.26000  ? 142 ALA A O   1 
ATOM   911  C CB  . ALA A 1 142 ? 29.53700 25.03400  144.30100 1.000 8.37000  ? 142 ALA A CB  1 
ATOM   912  N N   . ARG A 1 143 ? 29.34100 22.50200  142.04800 1.000 6.95000  ? 143 ARG A N   1 
ATOM   913  C CA  . ARG A 1 143 ? 29.89000 21.25100  141.53900 1.000 5.60000  ? 143 ARG A CA  1 
ATOM   914  C C   . ARG A 1 143 ? 31.29400 21.42600  140.97700 1.000 7.30000  ? 143 ARG A C   1 
ATOM   915  O O   . ARG A 1 143 ? 31.64500 22.48000  140.43700 1.000 7.16000  ? 143 ARG A O   1 
ATOM   916  C CB  . ARG A 1 143 ? 28.99900 20.66300  140.44600 1.000 6.34000  ? 143 ARG A CB  1 
ATOM   917  C CG  . ARG A 1 143 ? 27.62800 20.23800  140.95800 1.000 8.59000  ? 143 ARG A CG  1 
ATOM   918  C CD  . ARG A 1 143 ? 26.68200 19.87600  139.81700 1.000 7.16000  ? 143 ARG A CD  1 
ATOM   919  N NE  . ARG A 1 143 ? 26.43800 20.99800  138.90600 1.000 8.57000  ? 143 ARG A NE  1 
ATOM   920  C CZ  . ARG A 1 143 ? 25.61700 20.95200  137.86400 1.000 10.88000 ? 143 ARG A CZ  1 
ATOM   921  N NH1 . ARG A 1 143 ? 25.47000 22.02500  137.08800 1.000 10.88000 ? 143 ARG A NH1 1 
ATOM   922  N NH2 . ARG A 1 143 ? 24.94200 19.83800  137.58700 1.000 8.17000  ? 143 ARG A NH2 1 
ATOM   923  N N   . ALA A 1 144 ? 32.06900 20.35300  141.07800 1.000 6.54000  ? 144 ALA A N   1 
ATOM   924  C CA  . ALA A 1 144 ? 33.34900 20.19600  140.40200 1.000 6.69000  ? 144 ALA A CA  1 
ATOM   925  C C   . ALA A 1 144 ? 33.12100 19.85600  138.93000 1.000 8.18000  ? 144 ALA A C   1 
ATOM   926  O O   . ALA A 1 144 ? 32.03300 19.41000  138.54900 1.000 6.19000  ? 144 ALA A O   1 
ATOM   927  C CB  . ALA A 1 144 ? 34.15400 19.09200  141.09200 1.000 6.93000  ? 144 ALA A CB  1 
ATOM   928  N N   . PRO A 1 145 ? 34.13400 20.05500  138.06600 1.000 6.75000  ? 145 PRO A N   1 
ATOM   929  C CA  . PRO A 1 145 ? 35.47300 20.59100  138.33300 1.000 7.53000  ? 145 PRO A CA  1 
ATOM   930  C C   . PRO A 1 145 ? 35.51500 22.10700  138.43000 1.000 8.51000  ? 145 PRO A C   1 
ATOM   931  O O   . PRO A 1 145 ? 36.53700 22.62400  138.89400 1.000 10.45000 ? 145 PRO A O   1 
ATOM   932  C CB  . PRO A 1 145 ? 36.27700 20.12600  137.11300 1.000 9.94000  ? 145 PRO A CB  1 
ATOM   933  C CG  . PRO A 1 145 ? 35.27500 20.15700  136.01800 1.000 8.87000  ? 145 PRO A CG  1 
ATOM   934  C CD  . PRO A 1 145 ? 34.00800 19.61800  136.66200 1.000 7.39000  ? 145 PRO A CD  1 
ATOM   935  N N   . GLU A 1 146 ? 34.45600 22.80300  137.99300 1.000 7.63000  ? 146 GLU A N   1 
ATOM   936  C CA  . GLU A 1 146 ? 34.46800 24.26600  138.03100 1.000 10.40000 ? 146 GLU A CA  1 
ATOM   937  C C   . GLU A 1 146 ? 34.78300 24.77200  139.42800 1.000 14.36000 ? 146 GLU A C   1 
ATOM   938  O O   . GLU A 1 146 ? 35.56800 25.71600  139.59900 1.000 11.14000 ? 146 GLU A O   1 
ATOM   939  C CB  . GLU A 1 146 ? 33.12800 24.83700  137.56400 1.000 12.95000 ? 146 GLU A CB  1 
ATOM   940  C CG  . GLU A 1 146 ? 32.77500 24.50400  136.11500 1.000 9.81000  ? 146 GLU A CG  1 
ATOM   941  C CD  . GLU A 1 146 ? 31.77800 23.35800  136.01800 1.000 14.82000 ? 146 GLU A CD  1 
ATOM   942  O OE1 . GLU A 1 146 ? 31.93400 22.37300  136.78100 1.000 9.35000  ? 146 GLU A OE1 1 
ATOM   943  O OE2 . GLU A 1 146 ? 30.83900 23.44200  135.18900 1.000 12.54000 ? 146 GLU A OE2 1 
ATOM   944  N N   . ALA A 1 147 ? 34.17600 24.14900  140.44000 1.000 9.10000  ? 147 ALA A N   1 
ATOM   945  C CA  . ALA A 1 147 ? 34.39500 24.47200  141.85000 1.000 10.98000 ? 147 ALA A CA  1 
ATOM   946  C C   . ALA A 1 147 ? 34.85900 23.20300  142.54900 1.000 10.03000 ? 147 ALA A C   1 
ATOM   947  O O   . ALA A 1 147 ? 34.03400 22.38000  142.98500 1.000 8.29000  ? 147 ALA A O   1 
ATOM   948  C CB  . ALA A 1 147 ? 33.11600 25.02400  142.48500 1.000 10.16000 ? 147 ALA A CB  1 
ATOM   949  N N   . PRO A 1 148 ? 36.16500 22.99000  142.66200 1.000 10.71000 ? 148 PRO A N   1 
ATOM   950  C CA  . PRO A 1 148 ? 36.66700 21.75100  143.27300 1.000 9.85000  ? 148 PRO A CA  1 
ATOM   951  C C   . PRO A 1 148 ? 36.40900 21.72900  144.77400 1.000 8.09000  ? 148 PRO A C   1 
ATOM   952  O O   . PRO A 1 148 ? 35.97000 22.70900  145.37700 1.000 8.46000  ? 148 PRO A O   1 
ATOM   953  C CB  . PRO A 1 148 ? 38.17200 21.77600  142.98300 1.000 13.81000 ? 148 PRO A CB  1 
ATOM   954  C CG  . PRO A 1 148 ? 38.36800 22.84700  141.95200 1.000 16.21000 ? 148 PRO A CG  1 
ATOM   955  C CD  . PRO A 1 148 ? 37.24500 23.81900  142.10400 1.000 14.35000 ? 148 PRO A CD  1 
ATOM   956  N N   . PHE A 1 149 ? 36.69800 20.56700  145.37200 1.000 7.24000  ? 149 PHE A N   1 
ATOM   957  C CA  . PHE A 1 149 ? 36.71900 20.39400  146.82300 1.000 7.39000  ? 149 PHE A CA  1 
ATOM   958  C C   . PHE A 1 149 ? 37.45100 21.57500  147.44700 1.000 10.00000 ? 149 PHE A C   1 
ATOM   959  O O   . PHE A 1 149 ? 38.52900 21.94200  146.96200 1.000 8.85000  ? 149 PHE A O   1 
ATOM   960  C CB  . PHE A 1 149 ? 37.42200 19.09000  147.20900 1.000 7.08000  ? 149 PHE A CB  1 
ATOM   961  C CG  . PHE A 1 149 ? 37.71200 18.98000  148.68600 1.000 6.09000  ? 149 PHE A CG  1 
ATOM   962  C CD1 . PHE A 1 149 ? 36.75300 18.46800  149.54500 1.000 8.97000  ? 149 PHE A CD1 1 
ATOM   963  C CD2 . PHE A 1 149 ? 38.93800 19.38000  149.21500 1.000 8.48000  ? 149 PHE A CD2 1 
ATOM   964  C CE1 . PHE A 1 149 ? 37.00000 18.36200  150.92100 1.000 9.97000  ? 149 PHE A CE1 1 
ATOM   965  C CE2 . PHE A 1 149 ? 39.18900 19.28000  150.59400 1.000 8.33000  ? 149 PHE A CE2 1 
ATOM   966  C CZ  . PHE A 1 149 ? 38.21800 18.77100  151.43500 1.000 10.44000 ? 149 PHE A CZ  1 
ATOM   967  N N   . PRO A 1 150 ? 36.94500 22.16500  148.54500 1.000 7.77000  ? 150 PRO A N   1 
ATOM   968  C CA  . PRO A 1 150 ? 35.76600 21.76200  149.33100 1.000 6.02000  ? 150 PRO A CA  1 
ATOM   969  C C   . PRO A 1 150 ? 34.45400 22.48000  148.99800 1.000 8.59000  ? 150 PRO A C   1 
ATOM   970  O O   . PRO A 1 150 ? 33.58300 22.53300  149.86600 1.000 8.22000  ? 150 PRO A O   1 
ATOM   971  C CB  . PRO A 1 150 ? 36.18800 22.12100  150.75900 1.000 6.89000  ? 150 PRO A CB  1 
ATOM   972  C CG  . PRO A 1 150 ? 36.95500 23.41300  150.56100 1.000 9.54000  ? 150 PRO A CG  1 
ATOM   973  C CD  . PRO A 1 150 ? 37.73700 23.19400  149.25000 1.000 10.45000 ? 150 PRO A CD  1 
ATOM   974  N N   . ALA A 1 151 ? 34.29800 22.99100  147.77200 1.000 8.29000  ? 151 ALA A N   1 
ATOM   975  C CA  . ALA A 1 151 ? 33.18400 23.89700  147.49100 1.000 8.36000  ? 151 ALA A CA  1 
ATOM   976  C C   . ALA A 1 151 ? 31.82900 23.24100  147.75200 1.000 7.37000  ? 151 ALA A C   1 
ATOM   977  O O   . ALA A 1 151 ? 30.93200 23.87400  148.31900 1.000 6.91000  ? 151 ALA A O   1 
ATOM   978  C CB  . ALA A 1 151 ? 33.26000 24.40200  146.04800 1.000 9.41000  ? 151 ALA A CB  1 
ATOM   979  N N   . ALA A 1 152 ? 31.65300 21.98000  147.33300 1.000 7.72000  ? 152 ALA A N   1 
ATOM   980  C CA  . ALA A 1 152 ? 30.34400 21.33900  147.48100 1.000 8.02000  ? 152 ALA A CA  1 
ATOM   981  C C   . ALA A 1 152 ? 29.96100 21.23400  148.94700 1.000 6.98000  ? 152 ALA A C   1 
ATOM   982  O O   . ALA A 1 152 ? 28.82200 21.52900  149.32800 1.000 6.43000  ? 152 ALA A O   1 
ATOM   983  C CB  . ALA A 1 152 ? 30.34800 19.95300  146.84100 1.000 7.29000  ? 152 ALA A CB  1 
ATOM   984  N N   . ILE A 1 153 ? 30.91500 20.80600  149.77700 1.000 5.89000  ? 153 ILE A N   1 
ATOM   985  C CA  . ILE A 1 153 ? 30.69400 20.63500  151.21300 1.000 7.67000  ? 153 ILE A CA  1 
ATOM   986  C C   . ILE A 1 153 ? 30.29200 21.94900  151.86100 1.000 8.17000  ? 153 ILE A C   1 
ATOM   987  O O   . ILE A 1 153 ? 29.41900 21.98800  152.74000 1.000 7.67000  ? 153 ILE A O   1 
ATOM   988  C CB  . ILE A 1 153 ? 31.97400 20.07700  151.86900 1.000 10.25000 ? 153 ILE A CB  1 
ATOM   989  C CG1 . ILE A 1 153 ? 32.20900 18.62200  151.48100 1.000 17.04000 ? 153 ILE A CG1 1 
ATOM   990  C CG2 . ILE A 1 153 ? 31.96500 20.31700  153.38800 1.000 17.64000 ? 153 ILE A CG2 1 
ATOM   991  C CD1 . ILE A 1 153 ? 30.95000 17.77800  151.45100 1.000 10.74000 ? 153 ILE A CD1 1 
ATOM   992  N N   . LEU A 1 154 ? 30.96900 23.03900  151.48900 1.000 7.41000  ? 154 LEU A N   1 
ATOM   993  C CA  . LEU A 1 154 ? 30.69500 24.31700  152.13100 1.000 7.71000  ? 154 LEU A CA  1 
ATOM   994  C C   . LEU A 1 154 ? 29.31400 24.83300  151.76300 1.000 8.48000  ? 154 LEU A C   1 
ATOM   995  O O   . LEU A 1 154 ? 28.65500 25.46800  152.59100 1.000 7.90000  ? 154 LEU A O   1 
ATOM   996  C CB  . LEU A 1 154 ? 31.77100 25.33100  151.75300 1.000 9.61000  ? 154 LEU A CB  1 
ATOM   997  C CG  . LEU A 1 154 ? 33.17300 24.91800  152.20200 1.000 11.80000 ? 154 LEU A CG  1 
ATOM   998  C CD1 . LEU A 1 154 ? 34.20700 25.88000  151.64500 1.000 13.48000 ? 154 LEU A CD1 1 
ATOM   999  C CD2 . LEU A 1 154 ? 33.25300 24.85100  153.73100 1.000 14.54000 ? 154 LEU A CD2 1 
ATOM   1000 N N   . ASP A 1 155 ? 28.86100 24.56400  150.53600 1.000 7.15000  ? 155 ASP A N   1 
ATOM   1001 C CA  . ASP A 1 155 ? 27.49000 24.90500  150.15800 1.000 6.34000  ? 155 ASP A CA  1 
ATOM   1002 C C   . ASP A 1 155 ? 26.48200 24.04800  150.91700 1.000 6.85000  ? 155 ASP A C   1 
ATOM   1003 O O   . ASP A 1 155 ? 25.45500 24.55300  151.39300 1.000 8.07000  ? 155 ASP A O   1 
ATOM   1004 C CB  . ASP A 1 155 ? 27.29500 24.72600  148.65000 1.000 6.71000  ? 155 ASP A CB  1 
ATOM   1005 C CG  . ASP A 1 155 ? 27.63500 25.98200  147.84400 1.000 11.72000 ? 155 ASP A CG  1 
ATOM   1006 O OD1 . ASP A 1 155 ? 28.13400 26.97400  148.42600 1.000 9.98000  ? 155 ASP A OD1 1 
ATOM   1007 O OD2 . ASP A 1 155 ? 27.39000 25.96900  146.61100 1.000 9.54000  ? 155 ASP A OD2 1 
ATOM   1008 N N   . CYS A 1 156 ? 26.73200 22.73700  151.00100 1.000 6.57000  ? 156 CYS A N   1 
ATOM   1009 C CA  . CYS A 1 156 ? 25.80900 21.86400  151.72400 1.000 5.08000  ? 156 CYS A CA  1 
ATOM   1010 C C   . CYS A 1 156 ? 25.71300 22.27300  153.18800 1.000 5.33000  ? 156 CYS A C   1 
ATOM   1011 O O   . CYS A 1 156 ? 24.61400 22.31700  153.75700 1.000 5.63000  ? 156 CYS A O   1 
ATOM   1012 C CB  . CYS A 1 156 ? 26.24700 20.40300  151.60300 1.000 5.65000  ? 156 CYS A CB  1 
ATOM   1013 S SG  . CYS A 1 156 ? 26.03300 19.71700  149.94300 1.000 7.09000  ? 156 CYS A SG  1 
ATOM   1014 N N   . GLU A 1 157 ? 26.84900 22.60500  153.80700 1.000 5.96000  ? 157 GLU A N   1 
ATOM   1015 C CA  . GLU A 1 157 ? 26.81500 23.06500  155.19300 1.000 5.90000  ? 157 GLU A CA  1 
ATOM   1016 C C   . GLU A 1 157 ? 26.04200 24.37500  155.32400 1.000 6.89000  ? 157 GLU A C   1 
ATOM   1017 O O   . GLU A 1 157 ? 25.18400 24.51800  156.20300 1.000 6.63000  ? 157 GLU A O   1 
ATOM   1018 C CB  . GLU A 1 157 ? 28.23100 23.22500  155.74300 1.000 7.66000  ? 157 GLU A CB  1 
ATOM   1019 C CG  . GLU A 1 157 ? 28.23000 23.73300  157.18800 1.000 7.41000  ? 157 GLU A CG  1 
ATOM   1020 C CD  . GLU A 1 157 ? 29.56800 24.30500  157.64300 1.000 10.99000 ? 157 GLU A CD  1 
ATOM   1021 O OE1 . GLU A 1 157 ? 30.43700 24.58200  156.77900 1.000 10.98000 ? 157 GLU A OE1 1 
ATOM   1022 O OE2 . GLU A 1 157 ? 29.74900 24.46600  158.87700 1.000 11.83000 ? 157 GLU A OE2 1 
ATOM   1023 N N   . ALA A 1 158 ? 26.33000 25.34700  154.45700 1.000 6.77000  ? 158 ALA A N   1 
ATOM   1024 C CA  . ALA A 1 158 ? 25.64900 26.64000  154.54900 1.000 8.28000  ? 158 ALA A CA  1 
ATOM   1025 C C   . ALA A 1 158 ? 24.13500 26.49200  154.40300 1.000 7.06000  ? 158 ALA A C   1 
ATOM   1026 O O   . ALA A 1 158 ? 23.36900 27.10200  155.16200 1.000 7.96000  ? 158 ALA A O   1 
ATOM   1027 C CB  . ALA A 1 158 ? 26.19800 27.59900  153.49300 1.000 8.07000  ? 158 ALA A CB  1 
ATOM   1028 N N   . ALA A 1 159 ? 23.68400 25.69700  153.42200 1.000 7.11000  ? 159 ALA A N   1 
ATOM   1029 C CA  . ALA A 1 159 ? 22.24700 25.49700  153.24000 1.000 7.87000  ? 159 ALA A CA  1 
ATOM   1030 C C   . ALA A 1 159 ? 21.62100 24.85200  154.46900 1.000 6.44000  ? 159 ALA A C   1 
ATOM   1031 O O   . ALA A 1 159 ? 20.53300 25.24900  154.89900 1.000 6.04000  ? 159 ALA A O   1 
ATOM   1032 C CB  . ALA A 1 159 ? 21.96800 24.65400  151.98900 1.000 7.96000  ? 159 ALA A CB  1 
ATOM   1033 N N   . THR A 1 160 ? 22.29100 23.85200  155.04700 1.000 6.70000  ? 160 THR A N   1 
ATOM   1034 C CA  . THR A 1 160 ? 21.73700 23.17300  156.21600 1.000 7.35000  ? 160 THR A CA  1 
ATOM   1035 C C   . THR A 1 160 ? 21.62700 24.12900  157.40000 1.000 7.81000  ? 160 THR A C   1 
ATOM   1036 O O   . THR A 1 160 ? 20.60400 24.15400  158.09600 1.000 5.80000  ? 160 THR A O   1 
ATOM   1037 C CB  . THR A 1 160 ? 22.59100 21.95500  156.58800 1.000 5.14000  ? 160 THR A CB  1 
ATOM   1038 O OG1 . THR A 1 160 ? 22.75500 21.09600  155.44600 1.000 5.97000  ? 160 THR A OG1 1 
ATOM   1039 C CG2 . THR A 1 160 ? 21.90000 21.15400  157.68200 1.000 5.97000  ? 160 THR A CG2 1 
ATOM   1040 N N   . ARG A 1 161 ? 22.67100 24.92700  157.64600 1.000 6.29000  ? 161 ARG A N   1 
ATOM   1041 C CA  . ARG A 1 161 ? 22.59300 25.90200  158.73300 1.000 7.52000  ? 161 ARG A CA  1 
ATOM   1042 C C   . ARG A 1 161 ? 21.47900 26.90900  158.48900 1.000 7.44000  ? 161 ARG A C   1 
ATOM   1043 O O   . ARG A 1 161 ? 20.80600 27.34200  159.43200 1.000 6.44000  ? 161 ARG A O   1 
ATOM   1044 C CB  . ARG A 1 161 ? 23.92700 26.62800  158.89400 1.000 7.35000  ? 161 ARG A CB  1 
ATOM   1045 C CG  . ARG A 1 161 ? 25.03100 25.75800  159.48000 1.000 7.19000  ? 161 ARG A CG  1 
ATOM   1046 C CD  . ARG A 1 161 ? 26.32000 26.56300  159.67100 1.000 6.47000  ? 161 ARG A CD  1 
ATOM   1047 N NE  . ARG A 1 161 ? 27.41600 25.69400  160.08800 1.000 7.70000  ? 161 ARG A NE  1 
ATOM   1048 C CZ  . ARG A 1 161 ? 27.56500 25.22700  161.32600 1.000 8.56000  ? 161 ARG A CZ  1 
ATOM   1049 N NH1 . ARG A 1 161 ? 28.58000 24.42700  161.61900 1.000 6.53000  ? 161 ARG A NH1 1 
ATOM   1050 N NH2 . ARG A 1 161 ? 26.69600 25.55700  162.27200 1.000 7.37000  ? 161 ARG A NH2 1 
ATOM   1051 N N   . TRP A 1 162 ? 21.27000 27.29300  157.23200 1.000 8.99000  ? 162 TRP A N   1 
ATOM   1052 C CA  . TRP A 1 162 ? 20.21800 28.25600  156.92800 1.000 8.69000  ? 162 TRP A CA  1 
ATOM   1053 C C   . TRP A 1 162 ? 18.84100 27.64800  157.16600 1.000 7.94000  ? 162 TRP A C   1 
ATOM   1054 O O   . TRP A 1 162 ? 17.98900 28.26200  157.81800 1.000 8.33000  ? 162 TRP A O   1 
ATOM   1055 C CB  . TRP A 1 162 ? 20.37600 28.74700  155.48900 1.000 8.83000  ? 162 TRP A CB  1 
ATOM   1056 C CG  . TRP A 1 162 ? 19.39200 29.79300  155.06000 1.000 7.89000  ? 162 TRP A CG  1 
ATOM   1057 C CD1 . TRP A 1 162 ? 19.46100 31.13300  155.30500 1.000 12.83000 ? 162 TRP A CD1 1 
ATOM   1058 C CD2 . TRP A 1 162 ? 18.20400 29.58600  154.28600 1.000 7.25000  ? 162 TRP A CD2 1 
ATOM   1059 N NE1 . TRP A 1 162 ? 18.38600 31.77600  154.73000 1.000 10.94000 ? 162 TRP A NE1 1 
ATOM   1060 C CE2 . TRP A 1 162 ? 17.60200 30.84600  154.09900 1.000 10.10000 ? 162 TRP A CE2 1 
ATOM   1061 C CE3 . TRP A 1 162 ? 17.60000 28.46000  153.71700 1.000 8.02000  ? 162 TRP A CE3 1 
ATOM   1062 C CZ2 . TRP A 1 162 ? 16.42900 31.00600  153.37300 1.000 11.50000 ? 162 TRP A CZ2 1 
ATOM   1063 C CZ3 . TRP A 1 162 ? 16.42800 28.62300  153.00000 1.000 11.38000 ? 162 TRP A CZ3 1 
ATOM   1064 C CH2 . TRP A 1 162 ? 15.85300 29.88600  152.83900 1.000 12.77000 ? 162 TRP A CH2 1 
ATOM   1065 N N   . ILE A 1 163 ? 18.61300 26.43000  156.66200 1.000 7.39000  ? 163 ILE A N   1 
ATOM   1066 C CA  . ILE A 1 163 ? 17.34600 25.73600  156.90100 1.000 7.30000  ? 163 ILE A CA  1 
ATOM   1067 C C   . ILE A 1 163 ? 17.08100 25.60500  158.39500 1.000 8.63000  ? 163 ILE A C   1 
ATOM   1068 O O   . ILE A 1 163 ? 15.95600 25.83600  158.86700 1.000 7.75000  ? 163 ILE A O   1 
ATOM   1069 C CB  . ILE A 1 163 ? 17.35500 24.35600  156.21700 1.000 7.18000  ? 163 ILE A CB  1 
ATOM   1070 C CG1 . ILE A 1 163 ? 17.35700 24.49300  154.69700 1.000 6.24000  ? 163 ILE A CG1 1 
ATOM   1071 C CG2 . ILE A 1 163 ? 16.17200 23.50600  156.69100 1.000 8.14000  ? 163 ILE A CG2 1 
ATOM   1072 C CD1 . ILE A 1 163 ? 17.92500 23.26200  153.98600 1.000 7.96000  ? 163 ILE A CD1 1 
ATOM   1073 N N   . ALA A 1 164 ? 18.11900 25.24700  159.16300 1.000 6.25000  ? 164 ALA A N   1 
ATOM   1074 C CA  . ALA A 1 164 ? 17.98700 25.04200  160.60100 1.000 7.14000  ? 164 ALA A CA  1 
ATOM   1075 C C   . ALA A 1 164 ? 17.61200 26.31200  161.35000 1.000 10.06000 ? 164 ALA A C   1 
ATOM   1076 O O   . ALA A 1 164 ? 17.15300 26.22500  162.49400 1.000 10.77000 ? 164 ALA A O   1 
ATOM   1077 C CB  . ALA A 1 164 ? 19.29400 24.49600  161.17600 1.000 9.22000  ? 164 ALA A CB  1 
ATOM   1078 N N   . SER A 1 165 ? 17.80300 27.48100  160.74000 1.000 8.66000  ? 165 SER A N   1 
ATOM   1079 C CA  . SER A 1 165 ? 17.48500 28.75400  161.37700 1.000 9.96000  ? 165 SER A CA  1 
ATOM   1080 C C   . SER A 1 165 ? 16.02300 29.16500  161.21500 1.000 14.28000 ? 165 SER A C   1 
ATOM   1081 O O   . SER A 1 165 ? 15.65400 30.25600  161.66500 1.000 12.75000 ? 165 SER A O   1 
ATOM   1082 C CB  . SER A 1 165 ? 18.39500 29.85600  160.81900 1.000 10.63000 ? 165 SER A CB  1 
ATOM   1083 O OG  . SER A 1 165 ? 17.99200 30.23400  159.51100 1.000 13.10000 ? 165 SER A OG  1 
ATOM   1084 N N   . SER A 1 166 ? 15.19400 28.32400  160.60300 1.000 9.06000  ? 166 SER A N   1 
ATOM   1085 C CA  . SER A 1 166 ? 13.78300 28.61900  160.36100 1.000 10.16000 ? 166 SER A CA  1 
ATOM   1086 C C   . SER A 1 166 ? 13.59600 29.96400  159.65400 1.000 12.04000 ? 166 SER A C   1 
ATOM   1087 O O   . SER A 1 166 ? 12.90000 30.85100  160.17000 1.000 12.14000 ? 166 SER A O   1 
ATOM   1088 C CB  . SER A 1 166 ? 12.98600 28.57700  161.65500 1.000 10.36000 ? 166 SER A CB  1 
ATOM   1089 O OG  . SER A 1 166 ? 13.06100 27.30400  162.27700 1.000 11.06000 ? 166 SER A OG  1 
ATOM   1090 N N   . PRO A 1 167 ? 14.18400 30.14700  158.47700 1.000 12.49000 ? 167 PRO A N   1 
ATOM   1091 C CA  . PRO A 1 167 ? 14.07800 31.44000  157.79200 1.000 12.36000 ? 167 PRO A CA  1 
ATOM   1092 C C   . PRO A 1 167 ? 12.67000 31.67300  157.26600 1.000 14.16000 ? 167 PRO A C   1 
ATOM   1093 O O   . PRO A 1 167 ? 11.95100 30.74000  156.90000 1.000 12.33000 ? 167 PRO A O   1 
ATOM   1094 C CB  . PRO A 1 167 ? 15.08700 31.31400  156.64600 1.000 14.77000 ? 167 PRO A CB  1 
ATOM   1095 C CG  . PRO A 1 167 ? 15.09800 29.83700  156.34700 1.000 12.58000 ? 167 PRO A CG  1 
ATOM   1096 C CD  . PRO A 1 167 ? 14.91600 29.14800  157.67200 1.000 11.80000 ? 167 PRO A CD  1 
ATOM   1097 N N   . ALA A 1 168 ? 12.27300 32.94800  157.24700 1.000 19.21000 ? 168 ALA A N   1 
ATOM   1098 C CA  . ALA A 1 168 ? 10.90500 33.28600  156.87000 1.000 21.32000 ? 168 ALA A CA  1 
ATOM   1099 C C   . ALA A 1 168 ? 10.58700 32.85100  155.44600 1.000 17.87000 ? 168 ALA A C   1 
ATOM   1100 O O   . ALA A 1 168 ? 9.45600  32.44000  155.16200 1.000 19.53000 ? 168 ALA A O   1 
ATOM   1101 C CB  . ALA A 1 168 ? 10.67000 34.78900  157.03500 1.000 22.48000 ? 168 ALA A CB  1 
ATOM   1102 N N   . GLU A 1 169 ? 11.56900 32.90200  154.54400 1.000 17.63000 ? 169 GLU A N   1 
ATOM   1103 C CA  . GLU A 1 169 ? 11.28400 32.58000  153.14900 1.000 20.62000 ? 169 GLU A CA  1 
ATOM   1104 C C   . GLU A 1 169 ? 11.01100 31.09800  152.93200 1.000 22.04000 ? 169 GLU A C   1 
ATOM   1105 O O   . GLU A 1 169 ? 10.39000 30.73700  151.92700 1.000 20.13000 ? 169 GLU A O   1 
ATOM   1106 C CB  . GLU A 1 169 ? 12.43300 33.04300  152.25500 1.000 27.71000 ? 169 GLU A CB  1 
ATOM   1107 C CG  . GLU A 1 169 ? 13.78900 32.77100  152.83500 1.000 30.51000 ? 169 GLU A CG  1 
ATOM   1108 C CD  . GLU A 1 169 ? 14.45200 34.01000  153.41900 1.000 40.26000 ? 169 GLU A CD  1 
ATOM   1109 O OE1 . GLU A 1 169 ? 14.11200 34.38200  154.57300 1.000 27.89000 ? 169 GLU A OE1 1 
ATOM   1110 O OE2 . GLU A 1 169 ? 15.31800 34.59900  152.73000 1.000 45.26000 ? 169 GLU A OE2 1 
ATOM   1111 N N   . LEU A 1 170 ? 11.44300 30.23000  153.84700 1.000 17.67000 ? 170 LEU A N   1 
ATOM   1112 C CA  . LEU A 1 170 ? 11.05200 28.82700  153.77100 1.000 16.26000 ? 170 LEU A CA  1 
ATOM   1113 C C   . LEU A 1 170 ? 9.66800  28.59000  154.35300 1.000 18.24000 ? 170 LEU A C   1 
ATOM   1114 O O   . LEU A 1 170 ? 8.94000  27.71300  153.87400 1.000 19.28000 ? 170 LEU A O   1 
ATOM   1115 C CB  . LEU A 1 170 ? 12.06300 27.95200  154.51200 1.000 18.20000 ? 170 LEU A CB  1 
ATOM   1116 C CG  . LEU A 1 170 ? 13.03100 27.05400  153.75800 1.000 22.73000 ? 170 LEU A CG  1 
ATOM   1117 C CD1 . LEU A 1 170 ? 13.63200 26.06100  154.74700 1.000 13.19000 ? 170 LEU A CD1 1 
ATOM   1118 C CD2 . LEU A 1 170 ? 12.36200 26.34200  152.57600 1.000 17.46000 ? 170 LEU A CD2 1 
ATOM   1119 N N   . GLY A 1 171 ? 9.29800  29.33400  155.39300 1.000 17.01000 ? 171 GLY A N   1 
ATOM   1120 C CA  . GLY A 1 171 ? 7.99900  29.18500  156.00600 1.000 17.50000 ? 171 GLY A CA  1 
ATOM   1121 C C   . GLY A 1 171 ? 7.87500  28.04600  156.99200 1.000 18.60000 ? 171 GLY A C   1 
ATOM   1122 O O   . GLY A 1 171 ? 6.75900  27.73800  157.41700 1.000 19.01000 ? 171 GLY A O   1 
ATOM   1123 N N   . LEU A 1 172 ? 8.97900  27.40800  157.37300 1.000 12.40000 ? 172 LEU A N   1 
ATOM   1124 C CA  . LEU A 1 172 ? 8.94200  26.27000  158.27700 1.000 14.30000 ? 172 LEU A CA  1 
ATOM   1125 C C   . LEU A 1 172 ? 9.52000  26.65300  159.63200 1.000 14.20000 ? 172 LEU A C   1 
ATOM   1126 O O   . LEU A 1 172 ? 10.42900 27.48300  159.72400 1.000 15.42000 ? 172 LEU A O   1 
ATOM   1127 C CB  . LEU A 1 172 ? 9.73500  25.08700  157.70300 1.000 12.88000 ? 172 LEU A CB  1 
ATOM   1128 C CG  . LEU A 1 172 ? 9.20600  24.50700  156.39500 1.000 14.41000 ? 172 LEU A CG  1 
ATOM   1129 C CD1 . LEU A 1 172 ? 10.28700 23.66400  155.72400 1.000 10.91000 ? 172 LEU A CD1 1 
ATOM   1130 C CD2 . LEU A 1 172 ? 7.93500  23.68800  156.64100 1.000 15.17000 ? 172 LEU A CD2 1 
ATOM   1131 N N   . THR A 1 173 ? 8.99100  26.03300  160.68700 1.000 13.30000 ? 173 THR A N   1 
ATOM   1132 C CA  . THR A 1 173 ? 9.59400  26.10600  162.01900 1.000 13.73000 ? 173 THR A CA  1 
ATOM   1133 C C   . THR A 1 173 ? 10.30500 24.77500  162.24000 1.000 10.08000 ? 173 THR A C   1 
ATOM   1134 O O   . THR A 1 173 ? 9.66600  23.75700  162.51600 1.000 10.98000 ? 173 THR A O   1 
ATOM   1135 C CB  . THR A 1 173 ? 8.54800  26.36500  163.09700 1.000 16.14000 ? 173 THR A CB  1 
ATOM   1136 O OG1 . THR A 1 173 ? 7.85900  27.59100  162.80700 1.000 17.79000 ? 173 THR A OG1 1 
ATOM   1137 C CG2 . THR A 1 173 ? 9.21000  26.47300  164.46400 1.000 16.42000 ? 173 THR A CG2 1 
ATOM   1138 N N   . ALA A 1 174 ? 11.62600 24.77900  162.09200 1.000 9.86000  ? 174 ALA A N   1 
ATOM   1139 C CA  . ALA A 1 174 ? 12.39800 23.54300  162.16000 1.000 11.26000 ? 174 ALA A CA  1 
ATOM   1140 C C   . ALA A 1 174 ? 12.67400 23.16900  163.61200 1.000 11.90000 ? 174 ALA A C   1 
ATOM   1141 O O   . ALA A 1 174 ? 13.19100 23.98500  164.38200 1.000 14.58000 ? 174 ALA A O   1 
ATOM   1142 C CB  . ALA A 1 174 ? 13.71300 23.70000  161.39500 1.000 11.16000 ? 174 ALA A CB  1 
ATOM   1143 N N   . SER A 1 175 ? 12.32200 21.93900  163.99400 1.000 8.40000  ? 175 SER A N   1 
ATOM   1144 C CA  . SER A 1 175 ? 12.69900 21.42600  165.30800 1.000 10.20000 ? 175 SER A CA  1 
ATOM   1145 C C   . SER A 1 175 ? 13.98200 20.60300  165.26500 1.000 10.80000 ? 175 SER A C   1 
ATOM   1146 O O   . SER A 1 175 ? 14.59700 20.36500  166.31500 1.000 9.39000  ? 175 SER A O   1 
ATOM   1147 C CB  . SER A 1 175 ? 11.56600 20.57900  165.89300 1.000 10.91000 ? 175 SER A CB  1 
ATOM   1148 O OG  . SER A 1 175 ? 11.28700 19.44500  165.08100 1.000 11.41000 ? 175 SER A OG  1 
ATOM   1149 N N   . GLY A 1 176 ? 14.40200 20.19400  164.07600 1.000 7.61000  ? 176 GLY A N   1 
ATOM   1150 C CA  . GLY A 1 176 ? 15.60800 19.40300  163.89500 1.000 8.23000  ? 176 GLY A CA  1 
ATOM   1151 C C   . GLY A 1 176 ? 15.79800 19.17800  162.41200 1.000 8.46000  ? 176 GLY A C   1 
ATOM   1152 O O   . GLY A 1 176 ? 14.90300 19.44300  161.60700 1.000 9.57000  ? 176 GLY A O   1 
ATOM   1153 N N   . ILE A 1 177 ? 16.97800 18.66800  162.06200 1.000 5.60000  ? 177 ILE A N   1 
ATOM   1154 C CA  . ILE A 1 177 ? 17.35300 18.42900  160.67200 1.000 7.87000  ? 177 ILE A CA  1 
ATOM   1155 C C   . ILE A 1 177 ? 17.51800 16.93000  160.46000 1.000 6.08000  ? 177 ILE A C   1 
ATOM   1156 O O   . ILE A 1 177 ? 18.16700 16.25300  161.26600 1.000 6.71000  ? 177 ILE A O   1 
ATOM   1157 C CB  . ILE A 1 177 ? 18.65700 19.15900  160.29500 1.000 8.18000  ? 177 ILE A CB  1 
ATOM   1158 C CG1 . ILE A 1 177 ? 18.47000 20.68100  160.33900 1.000 8.68000  ? 177 ILE A CG1 1 
ATOM   1159 C CG2 . ILE A 1 177 ? 19.15800 18.70100  158.90200 1.000 8.20000  ? 177 ILE A CG2 1 
ATOM   1160 C CD1 . ILE A 1 177 ? 17.52500 21.21800  159.27900 1.000 11.11000 ? 177 ILE A CD1 1 
ATOM   1161 N N   . ILE A 1 178 ? 16.94700 16.41900  159.37200 1.000 3.86000  ? 178 ILE A N   1 
ATOM   1162 C CA  . ILE A 1 178 ? 17.21800 15.07100  158.88600 1.000 4.71000  ? 178 ILE A CA  1 
ATOM   1163 C C   . ILE A 1 178 ? 18.06600 15.20900  157.63000 1.000 5.45000  ? 178 ILE A C   1 
ATOM   1164 O O   . ILE A 1 178 ? 17.57300 15.68000  156.59800 1.000 5.67000  ? 178 ILE A O   1 
ATOM   1165 C CB  . ILE A 1 178 ? 15.92800 14.30400  158.58400 1.000 5.12000  ? 178 ILE A CB  1 
ATOM   1166 C CG1 . ILE A 1 178 ? 15.08000 14.14700  159.84000 1.000 5.91000  ? 178 ILE A CG1 1 
ATOM   1167 C CG2 . ILE A 1 178 ? 16.24400 12.95000  157.93500 1.000 5.56000  ? 178 ILE A CG2 1 
ATOM   1168 C CD1 . ILE A 1 178 ? 13.59800 13.99500  159.50900 1.000 7.77000  ? 178 ILE A CD1 1 
ATOM   1169 N N   . THR A 1 179 ? 19.33300 14.79500  157.69200 1.000 4.79000  ? 179 THR A N   1 
ATOM   1170 C CA  . THR A 1 179 ? 20.17900 14.83200  156.49900 1.000 4.73000  ? 179 THR A CA  1 
ATOM   1171 C C   . THR A 1 179 ? 20.07300 13.51600  155.74100 1.000 5.40000  ? 179 THR A C   1 
ATOM   1172 O O   . THR A 1 179 ? 19.99700 12.44300  156.34400 1.000 4.99000  ? 179 THR A O   1 
ATOM   1173 C CB  . THR A 1 179 ? 21.64100 15.08800  156.85300 1.000 5.18000  ? 179 THR A CB  1 
ATOM   1174 O OG1 . THR A 1 179 ? 22.05300 14.15400  157.86300 1.000 5.25000  ? 179 THR A OG1 1 
ATOM   1175 C CG2 . THR A 1 179 ? 21.83300 16.50500  157.36200 1.000 6.00000  ? 179 THR A CG2 1 
ATOM   1176 N N   . ILE A 1 180 ? 20.08300 13.59800  154.41000 1.000 3.70000  ? 180 ILE A N   1 
ATOM   1177 C CA  . ILE A 1 180 ? 19.96900 12.40400  153.58500 1.000 3.97000  ? 180 ILE A CA  1 
ATOM   1178 C C   . ILE A 1 180 ? 20.61800 12.69000  152.24200 1.000 4.99000  ? 180 ILE A C   1 
ATOM   1179 O O   . ILE A 1 180 ? 20.59800 13.81900  151.74500 1.000 5.19000  ? 180 ILE A O   1 
ATOM   1180 C CB  . ILE A 1 180 ? 18.49300 11.96100  153.43800 1.000 4.55000  ? 180 ILE A CB  1 
ATOM   1181 C CG1 . ILE A 1 180 ? 18.37900 10.67900  152.60900 1.000 6.25000  ? 180 ILE A CG1 1 
ATOM   1182 C CG2 . ILE A 1 180 ? 17.66300 13.06400  152.81600 1.000 8.05000  ? 180 ILE A CG2 1 
ATOM   1183 C CD1 . ILE A 1 180 ? 17.06600 9.95000   152.83000 1.000 8.44000  ? 180 ILE A CD1 1 
ATOM   1184 N N   . GLY A 1 181 ? 21.24200 11.66800  151.67100 1.000 4.87000  ? 181 GLY A N   1 
ATOM   1185 C CA  . GLY A 1 181 ? 21.84300 11.87500  150.37100 1.000 5.83000  ? 181 GLY A CA  1 
ATOM   1186 C C   . GLY A 1 181 ? 22.40000 10.59000  149.81400 1.000 6.57000  ? 181 GLY A C   1 
ATOM   1187 O O   . GLY A 1 181 ? 22.77700 9.70500   150.58300 1.000 7.47000  ? 181 GLY A O   1 
ATOM   1188 N N   . ASP A 1 182 ? 22.44500 10.47600  148.49100 1.000 6.76000  ? 182 ASP A N   1 
ATOM   1189 C CA  . ASP A 1 182 ? 22.93700 9.27800   147.82800 1.000 7.09000  ? 182 ASP A CA  1 
ATOM   1190 C C   . ASP A 1 182 ? 24.34400 9.52600   147.30800 1.000 7.60000  ? 182 ASP A C   1 
ATOM   1191 O O   . ASP A 1 182 ? 24.61400 10.56600  146.70300 1.000 6.02000  ? 182 ASP A O   1 
ATOM   1192 C CB  . ASP A 1 182 ? 22.01800 8.84600   146.67500 1.000 7.36000  ? 182 ASP A CB  1 
ATOM   1193 C CG  . ASP A 1 182 ? 21.89900 9.89500   145.58000 1.000 11.08000 ? 182 ASP A CG  1 
ATOM   1194 O OD1 . ASP A 1 182 ? 21.54400 11.04500  145.90500 1.000 9.96000  ? 182 ASP A OD1 1 
ATOM   1195 O OD2 . ASP A 1 182 ? 22.12600 9.55900   144.38800 1.000 11.83000 ? 182 ASP A OD2 1 
ATOM   1196 N N   . SER A 1 183 ? 25.24000 8.57700   147.57400 1.000 9.38000  ? 183 SER A N   1 
ATOM   1197 C CA  . SER A 1 183 ? 26.54500 8.55600   146.93200 1.000 7.94000  ? 183 SER A CA  1 
ATOM   1198 C C   . SER A 1 183 ? 27.41300 9.73700   147.37900 1.000 9.06000  ? 183 SER A C   1 
ATOM   1199 O O   . SER A 1 183 ? 27.74000 9.83600   148.56500 1.000 9.49000  ? 183 SER A O   1 
ATOM   1200 C CB  . SER A 1 183 ? 26.31600 8.52600   145.43400 1.000 12.59000 ? 183 SER A CB  1 
ATOM   1201 O OG  . SER A 1 183 ? 27.47200 8.06500   144.79000 1.000 14.69000 ? 183 SER A OG  1 
ATOM   1202 N N   . ALA A 1 184 ? 27.80900 10.63200  146.46400 1.000 7.50000  ? 184 ALA A N   1 
ATOM   1203 C CA  . ALA A 1 184 ? 28.50100 11.84700  146.90000 1.000 6.20000  ? 184 ALA A CA  1 
ATOM   1204 C C   . ALA A 1 184 ? 27.64200 12.63800  147.87100 1.000 6.27000  ? 184 ALA A C   1 
ATOM   1205 O O   . ALA A 1 184 ? 28.16500 13.30300  148.77700 1.000 4.78000  ? 184 ALA A O   1 
ATOM   1206 C CB  . ALA A 1 184 ? 28.87300 12.73000  145.69800 1.000 5.98000  ? 184 ALA A CB  1 
ATOM   1207 N N   . GLY A 1 185 ? 26.32100 12.58500  147.69300 1.000 5.67000  ? 185 GLY A N   1 
ATOM   1208 C CA  . GLY A 1 185 ? 25.42800 13.21300  148.64900 1.000 5.03000  ? 185 GLY A CA  1 
ATOM   1209 C C   . GLY A 1 185 ? 25.41900 12.52700  149.99600 1.000 5.43000  ? 185 GLY A C   1 
ATOM   1210 O O   . GLY A 1 185 ? 25.07400 13.16000  150.99900 1.000 6.59000  ? 185 GLY A O   1 
ATOM   1211 N N   . GLY A 1 186 ? 25.78500 11.25100  150.03800 1.000 5.32000  ? 186 GLY A N   1 
ATOM   1212 C CA  . GLY A 1 186 ? 25.94100 10.54600  151.29900 1.000 5.76000  ? 186 GLY A CA  1 
ATOM   1213 C C   . GLY A 1 186 ? 27.23800 10.95200  151.97300 1.000 6.46000  ? 186 GLY A C   1 
ATOM   1214 O O   . GLY A 1 186 ? 27.32800 11.01100  153.20300 1.000 5.48000  ? 186 GLY A O   1 
ATOM   1215 N N   . ASN A 1 187 ? 28.26900 11.19300  151.16000 1.000 5.06000  ? 187 ASN A N   1 
ATOM   1216 C CA  . ASN A 1 187 ? 29.48200 11.82200  151.67000 1.000 5.30000  ? 187 ASN A CA  1 
ATOM   1217 C C   . ASN A 1 187 ? 29.16000 13.17300  152.30000 1.000 5.17000  ? 187 ASN A C   1 
ATOM   1218 O O   . ASN A 1 187 ? 29.57400 13.45700  153.43100 1.000 5.59000  ? 187 ASN A O   1 
ATOM   1219 C CB  . ASN A 1 187 ? 30.49800 11.96500  150.53600 1.000 6.39000  ? 187 ASN A CB  1 
ATOM   1220 C CG  . ASN A 1 187 ? 31.75400 12.72300  150.94600 1.000 9.77000  ? 187 ASN A CG  1 
ATOM   1221 O OD1 . ASN A 1 187 ? 31.76700 13.95800  150.98600 1.000 8.05000  ? 187 ASN A OD1 1 
ATOM   1222 N ND2 . ASN A 1 187 ? 32.83100 11.98700  151.20200 1.000 8.61000  ? 187 ASN A ND2 1 
ATOM   1223 N N   . ALA A 1 188 ? 28.41600 14.01900  151.57900 1.000 4.53000  ? 188 ALA A N   1 
ATOM   1224 C CA  . ALA A 1 188 ? 28.05900 15.33400  152.10500 1.000 5.69000  ? 188 ALA A CA  1 
ATOM   1225 C C   . ALA A 1 188 ? 27.22900 15.20200  153.37400 1.000 6.05000  ? 188 ALA A C   1 
ATOM   1226 O O   . ALA A 1 188 ? 27.42400 15.96100  154.33000 1.000 5.45000  ? 188 ALA A O   1 
ATOM   1227 C CB  . ALA A 1 188 ? 27.30300 16.14400  151.04900 1.000 3.96000  ? 188 ALA A CB  1 
ATOM   1228 N N   . THR A 1 189 ? 26.32200 14.21800  153.41000 1.000 3.25000  ? 189 THR A N   1 
ATOM   1229 C CA  . THR A 1 189 ? 25.52400 13.97300  154.60900 1.000 4.51000  ? 189 THR A CA  1 
ATOM   1230 C C   . THR A 1 189 ? 26.41500 13.81700  155.83200 1.000 5.31000  ? 189 THR A C   1 
ATOM   1231 O O   . THR A 1 189 ? 26.21600 14.48500  156.85500 1.000 6.82000  ? 189 THR A O   1 
ATOM   1232 C CB  . THR A 1 189 ? 24.65900 12.72700  154.40700 1.000 5.33000  ? 189 THR A CB  1 
ATOM   1233 O OG1 . THR A 1 189 ? 23.66000 13.00800  153.41700 1.000 6.55000  ? 189 THR A OG1 1 
ATOM   1234 C CG2 . THR A 1 189 ? 23.97700 12.31100  155.70700 1.000 5.48000  ? 189 THR A CG2 1 
ATOM   1235 N N   . VAL A 1 190 ? 27.42300 12.95000  155.73700 1.000 3.96000  ? 190 VAL A N   1 
ATOM   1236 C CA  . VAL A 1 190 ? 28.24800 12.68000  156.91300 1.000 4.58000  ? 190 VAL A CA  1 
ATOM   1237 C C   . VAL A 1 190 ? 29.13200 13.87800  157.24100 1.000 4.69000  ? 190 VAL A C   1 
ATOM   1238 O O   . VAL A 1 190 ? 29.32400 14.21000  158.41300 1.000 4.65000  ? 190 VAL A O   1 
ATOM   1239 C CB  . VAL A 1 190 ? 29.07600 11.40100  156.70800 1.000 4.55000  ? 190 VAL A CB  1 
ATOM   1240 C CG1 . VAL A 1 190 ? 29.92500 11.12800  157.94600 1.000 5.93000  ? 190 VAL A CG1 1 
ATOM   1241 C CG2 . VAL A 1 190 ? 28.16000 10.21200  156.43500 1.000 4.98000  ? 190 VAL A CG2 1 
ATOM   1242 N N   . VAL A 1 191 ? 29.68000 14.55000  156.21900 1.000 4.21000  ? 191 VAL A N   1 
ATOM   1243 C CA  . VAL A 1 191 ? 30.54500 15.70300  156.48100 1.000 4.64000  ? 191 VAL A CA  1 
ATOM   1244 C C   . VAL A 1 191 ? 29.75100 16.82000  157.15400 1.000 5.59000  ? 191 VAL A C   1 
ATOM   1245 O O   . VAL A 1 191 ? 30.19800 17.41700  158.14500 1.000 6.56000  ? 191 VAL A O   1 
ATOM   1246 C CB  . VAL A 1 191 ? 31.21500 16.18900  155.18200 1.000 5.87000  ? 191 VAL A CB  1 
ATOM   1247 C CG1 . VAL A 1 191 ? 31.94200 17.50000  155.43400 1.000 5.62000  ? 191 VAL A CG1 1 
ATOM   1248 C CG2 . VAL A 1 191 ? 32.18400 15.12200  154.65200 1.000 7.51000  ? 191 VAL A CG2 1 
ATOM   1249 N N   . VAL A 1 192 ? 28.54800 17.10200  156.64300 1.000 5.86000  ? 192 VAL A N   1 
ATOM   1250 C CA  . VAL A 1 192 ? 27.72900 18.16400  157.22400 1.000 4.86000  ? 192 VAL A CA  1 
ATOM   1251 C C   . VAL A 1 192 ? 27.38400 17.82700  158.66900 1.000 6.65000  ? 192 VAL A C   1 
ATOM   1252 O O   . VAL A 1 192 ? 27.41400 18.69400  159.55400 1.000 5.48000  ? 192 VAL A O   1 
ATOM   1253 C CB  . VAL A 1 192 ? 26.46300 18.40100  156.37000 1.000 5.35000  ? 192 VAL A CB  1 
ATOM   1254 C CG1 . VAL A 1 192 ? 25.46100 19.25600  157.11200 1.000 7.25000  ? 192 VAL A CG1 1 
ATOM   1255 C CG2 . VAL A 1 192 ? 26.81300 19.07800  155.03700 1.000 6.29000  ? 192 VAL A CG2 1 
ATOM   1256 N N   . GLY A 1 193 ? 27.06400 16.55600  158.93500 1.000 3.78000  ? 193 GLY A N   1 
ATOM   1257 C CA  . GLY A 1 193 ? 26.78400 16.14700  160.29900 1.000 3.87000  ? 193 GLY A CA  1 
ATOM   1258 C C   . GLY A 1 193 ? 27.97000 16.34000  161.22700 1.000 5.88000  ? 193 GLY A C   1 
ATOM   1259 O O   . GLY A 1 193 ? 27.79900 16.66300  162.40400 1.000 5.32000  ? 193 GLY A O   1 
ATOM   1260 N N   . GLN A 1 194 ? 29.18600 16.12600  160.71600 1.000 3.74000  ? 194 GLN A N   1 
ATOM   1261 C CA  . GLN A 1 194 ? 30.37100 16.30300  161.54900 1.000 5.51000  ? 194 GLN A CA  1 
ATOM   1262 C C   . GLN A 1 194 ? 30.65000 17.77700  161.79600 1.000 5.74000  ? 194 GLN A C   1 
ATOM   1263 O O   . GLN A 1 194 ? 31.06600 18.15900  162.89800 1.000 5.56000  ? 194 GLN A O   1 
ATOM   1264 C CB  . GLN A 1 194 ? 31.58200 15.62300  160.90000 1.000 5.35000  ? 194 GLN A CB  1 
ATOM   1265 C CG  . GLN A 1 194 ? 31.51100 14.10000  160.98400 1.000 5.13000  ? 194 GLN A CG  1 
ATOM   1266 C CD  . GLN A 1 194 ? 32.62700 13.40500  160.22600 1.000 5.69000  ? 194 GLN A CD  1 
ATOM   1267 O OE1 . GLN A 1 194 ? 33.40600 14.04400  159.51900 1.000 7.59000  ? 194 GLN A OE1 1 
ATOM   1268 N NE2 . GLN A 1 194 ? 32.71100 12.08800  160.38000 1.000 4.70000  ? 194 GLN A NE2 1 
ATOM   1269 N N   . LEU A 1 195 ? 30.43000 18.61500  160.78000 1.000 5.28000  ? 195 LEU A N   1 
ATOM   1270 C CA  . LEU A 1 195 ? 30.63100 20.05200  160.94400 1.000 6.36000  ? 195 LEU A CA  1 
ATOM   1271 C C   . LEU A 1 195 ? 29.64400 20.62000  161.95200 1.000 7.61000  ? 195 LEU A C   1 
ATOM   1272 O O   . LEU A 1 195 ? 30.00500 21.46400  162.77900 1.000 6.85000  ? 195 LEU A O   1 
ATOM   1273 C CB  . LEU A 1 195 ? 30.48900 20.76100  159.59700 1.000 12.69000 ? 195 LEU A CB  1 
ATOM   1274 C CG  . LEU A 1 195 ? 31.60000 20.46800  158.58700 1.000 12.69000 ? 195 LEU A CG  1 
ATOM   1275 C CD1 . LEU A 1 195 ? 31.17200 20.86600  157.17300 1.000 12.69000 ? 195 LEU A CD1 1 
ATOM   1276 C CD2 . LEU A 1 195 ? 32.88200 21.18000  158.99500 1.000 12.69000 ? 195 LEU A CD2 1 
ATOM   1277 N N   . LEU A 1 196 ? 28.39700 20.14500  161.91400 1.000 5.97000  ? 196 LEU A N   1 
ATOM   1278 C CA  . LEU A 1 196 ? 27.38400 20.62300  162.84900 1.000 5.71000  ? 196 LEU A CA  1 
ATOM   1279 C C   . LEU A 1 196 ? 27.52900 19.99000  164.23300 1.000 6.60000  ? 196 LEU A C   1 
ATOM   1280 O O   . LEU A 1 196 ? 27.16000 20.61400  165.23000 1.000 9.55000  ? 196 LEU A O   1 
ATOM   1281 C CB  . LEU A 1 196 ? 25.98300 20.36600  162.28500 1.000 6.19000  ? 196 LEU A CB  1 
ATOM   1282 C CG  . LEU A 1 196 ? 25.38100 21.51600  161.46300 1.000 6.47000  ? 196 LEU A CG  1 
ATOM   1283 C CD1 . LEU A 1 196 ? 26.28900 21.89200  160.28800 1.000 8.39000  ? 196 LEU A CD1 1 
ATOM   1284 C CD2 . LEU A 1 196 ? 23.97200 21.15800  160.96300 1.000 8.01000  ? 196 LEU A CD2 1 
ATOM   1285 N N   . ALA A 1 197 ? 28.05400 18.76800  164.33100 1.000 5.20000  ? 197 ALA A N   1 
ATOM   1286 C CA  . ALA A 1 197 ? 28.34500 18.22600  165.65400 1.000 6.11000  ? 197 ALA A CA  1 
ATOM   1287 C C   . ALA A 1 197 ? 29.40800 19.06600  166.35300 1.000 9.72000  ? 197 ALA A C   1 
ATOM   1288 O O   . ALA A 1 197 ? 29.33800 19.29400  167.56700 1.000 9.62000  ? 197 ALA A O   1 
ATOM   1289 C CB  . ALA A 1 197 ? 28.80400 16.76500  165.55100 1.000 6.22000  ? 197 ALA A CB  1 
ATOM   1290 N N   . ALA A 1 198 ? 30.39800 19.53700  165.59300 1.000 5.55000  ? 198 ALA A N   1 
ATOM   1291 C CA  . ALA A 1 198 ? 31.49500 20.31800  166.15900 1.000 8.27000  ? 198 ALA A CA  1 
ATOM   1292 C C   . ALA A 1 198 ? 31.04800 21.73200  166.49700 1.000 9.12000  ? 198 ALA A C   1 
ATOM   1293 O O   . ALA A 1 198 ? 31.46000 22.29700  167.52100 1.000 8.17000  ? 198 ALA A O   1 
ATOM   1294 C CB  . ALA A 1 198 ? 32.66100 20.35500  165.16900 1.000 8.41000  ? 198 ALA A CB  1 
ATOM   1295 N N   . SER A 1 199 ? 30.18800 22.30000  165.65400 1.000 7.68000  ? 199 SER A N   1 
ATOM   1296 C CA  . SER A 1 199 ? 29.75900 23.69200  165.76300 1.000 8.48000  ? 199 SER A CA  1 
ATOM   1297 C C   . SER A 1 199 ? 28.26600 23.72000  165.45500 1.000 7.86000  ? 199 SER A C   1 
ATOM   1298 O O   . SER A 1 199 ? 27.86100 23.84500  164.29300 1.000 8.69000  ? 199 SER A O   1 
ATOM   1299 C CB  . SER A 1 199 ? 30.55000 24.58500  164.80500 1.000 10.72000 ? 199 SER A CB  1 
ATOM   1300 O OG  . SER A 1 199 ? 30.21600 25.95200  164.96500 1.000 12.31000 ? 199 SER A OG  1 
ATOM   1301 N N   . PRO A 1 200 ? 27.41800 23.58000  166.47500 1.000 9.77000  ? 200 PRO A N   1 
ATOM   1302 C CA  . PRO A 1 200 ? 25.99500 23.31000  166.22200 1.000 8.16000  ? 200 PRO A CA  1 
ATOM   1303 C C   . PRO A 1 200 ? 25.29200 24.41300  165.44300 1.000 9.09000  ? 200 PRO A C   1 
ATOM   1304 O O   . PRO A 1 200 ? 25.64100 25.59600  165.52400 1.000 9.88000  ? 200 PRO A O   1 
ATOM   1305 C CB  . PRO A 1 200 ? 25.40800 23.16500  167.63200 1.000 9.73000  ? 200 PRO A CB  1 
ATOM   1306 C CG  . PRO A 1 200 ? 26.56700 22.62200  168.44400 1.000 12.91000 ? 200 PRO A CG  1 
ATOM   1307 C CD  . PRO A 1 200 ? 27.78700 23.35100  167.88800 1.000 10.41000 ? 200 PRO A CD  1 
ATOM   1308 N N   . ALA A 1 201 ? 24.28800 23.99600  164.66800 1.000 6.91000  ? 201 ALA A N   1 
ATOM   1309 C CA  . ALA A 1 201 ? 23.34600 24.92000  164.05000 1.000 7.29000  ? 201 ALA A CA  1 
ATOM   1310 C C   . ALA A 1 201 ? 22.24500 25.23200  165.06200 1.000 8.35000  ? 201 ALA A C   1 
ATOM   1311 O O   . ALA A 1 201 ? 22.31300 24.83300  166.22800 1.000 8.91000  ? 201 ALA A O   1 
ATOM   1312 C CB  . ALA A 1 201 ? 22.79800 24.33100  162.75200 1.000 7.18000  ? 201 ALA A CB  1 
ATOM   1313 N N   . ALA A 1 202 ? 21.20600 25.95500  164.63000 1.000 9.04000  ? 202 ALA A N   1 
ATOM   1314 C CA  . ALA A 1 202 ? 20.18100 26.40800  165.57600 1.000 10.92000 ? 202 ALA A CA  1 
ATOM   1315 C C   . ALA A 1 202 ? 19.36000 25.25100  166.14100 1.000 9.41000  ? 202 ALA A C   1 
ATOM   1316 O O   . ALA A 1 202 ? 18.81300 25.35900  167.24900 1.000 9.90000  ? 202 ALA A O   1 
ATOM   1317 C CB  . ALA A 1 202 ? 19.26900 27.43000  164.89500 1.000 11.14000 ? 202 ALA A CB  1 
ATOM   1318 N N   . VAL A 1 203 ? 19.24600 24.15500  165.39700 1.000 8.43000  ? 203 VAL A N   1 
ATOM   1319 C CA  . VAL A 1 203 ? 18.63000 22.92400  165.88900 1.000 7.98000  ? 203 VAL A CA  1 
ATOM   1320 C C   . VAL A 1 203 ? 19.56100 21.76700  165.55200 1.000 7.44000  ? 203 VAL A C   1 
ATOM   1321 O O   . VAL A 1 203 ? 20.42100 21.88500  164.66000 1.000 7.41000  ? 203 VAL A O   1 
ATOM   1322 C CB  . VAL A 1 203 ? 17.21900 22.70500  165.28400 1.000 7.16000  ? 203 VAL A CB  1 
ATOM   1323 C CG1 . VAL A 1 203 ? 16.27800 23.82700  165.71300 1.000 12.90000 ? 203 VAL A CG1 1 
ATOM   1324 C CG2 . VAL A 1 203 ? 17.30000 22.61200  163.76500 1.000 8.22000  ? 203 VAL A CG2 1 
ATOM   1325 N N   . PRO A 1 204 ? 19.41400 20.63800  166.23600 1.000 8.40000  ? 204 PRO A N   1 
ATOM   1326 C CA  . PRO A 1 204 ? 20.30900 19.50200  165.99200 1.000 8.35000  ? 204 PRO A CA  1 
ATOM   1327 C C   . PRO A 1 204 ? 19.93800 18.71200  164.74700 1.000 7.63000  ? 204 PRO A C   1 
ATOM   1328 O O   . PRO A 1 204 ? 18.80000 18.72200  164.26800 1.000 7.16000  ? 204 PRO A O   1 
ATOM   1329 C CB  . PRO A 1 204 ? 20.13300 18.63300  167.24100 1.000 12.62000 ? 204 PRO A CB  1 
ATOM   1330 C CG  . PRO A 1 204 ? 18.76100 18.97000  167.74000 1.000 17.58000 ? 204 PRO A CG  1 
ATOM   1331 C CD  . PRO A 1 204 ? 18.55400 20.42300  167.41900 1.000 11.88000 ? 204 PRO A CD  1 
ATOM   1332 N N   . VAL A 1 205 ? 20.94100 18.00700  164.23300 1.000 6.78000  ? 205 VAL A N   1 
ATOM   1333 C CA  . VAL A 1 205 ? 20.68900 16.91700  163.29300 1.000 6.56000  ? 205 VAL A CA  1 
ATOM   1334 C C   . VAL A 1 205 ? 20.08600 15.76600  164.08900 1.000 6.06000  ? 205 VAL A C   1 
ATOM   1335 O O   . VAL A 1 205 ? 20.75500 15.18100  164.94900 1.000 8.82000  ? 205 VAL A O   1 
ATOM   1336 C CB  . VAL A 1 205 ? 21.96700 16.48200  162.57800 1.000 6.94000  ? 205 VAL A CB  1 
ATOM   1337 C CG1 . VAL A 1 205 ? 21.68600 15.25400  161.69800 1.000 6.08000  ? 205 VAL A CG1 1 
ATOM   1338 C CG2 . VAL A 1 205 ? 22.53600 17.64200  161.75900 1.000 7.12000  ? 205 VAL A CG2 1 
ATOM   1339 N N   . VAL A 1 206 ? 18.82100 15.43800  163.82000 1.000 5.59000  ? 206 VAL A N   1 
ATOM   1340 C CA  . VAL A 1 206 ? 18.14500 14.39700  164.59100 1.000 6.14000  ? 206 VAL A CA  1 
ATOM   1341 C C   . VAL A 1 206 ? 18.21700 13.03700  163.91700 1.000 6.18000  ? 206 VAL A C   1 
ATOM   1342 O O   . VAL A 1 206 ? 17.88600 12.02600  164.55600 1.000 5.26000  ? 206 VAL A O   1 
ATOM   1343 C CB  . VAL A 1 206 ? 16.67300 14.77500  164.88200 1.000 7.13000  ? 206 VAL A CB  1 
ATOM   1344 C CG1 . VAL A 1 206 ? 16.63200 16.03700  165.74700 1.000 7.93000  ? 206 VAL A CG1 1 
ATOM   1345 C CG2 . VAL A 1 206 ? 15.89400 14.96400  163.58600 1.000 7.44000  ? 206 VAL A CG2 1 
ATOM   1346 N N   . LEU A 1 207 ? 18.66900 12.97400  162.66700 1.000 5.03000  ? 207 LEU A N   1 
ATOM   1347 C CA  . LEU A 1 207 ? 18.81400 11.72100  161.93800 1.000 4.15000  ? 207 LEU A CA  1 
ATOM   1348 C C   . LEU A 1 207 ? 19.65300 11.99600  160.70100 1.000 4.84000  ? 207 LEU A C   1 
ATOM   1349 O O   . LEU A 1 207 ? 19.46200 13.02000  160.04400 1.000 5.73000  ? 207 LEU A O   1 
ATOM   1350 C CB  . LEU A 1 207 ? 17.44400 11.15000  161.53100 1.000 7.06000  ? 207 LEU A CB  1 
ATOM   1351 C CG  . LEU A 1 207 ? 17.48800 9.87300   160.69300 1.000 4.94000  ? 207 LEU A CG  1 
ATOM   1352 C CD1 . LEU A 1 207 ? 18.06200 8.73300   161.53700 1.000 6.83000  ? 207 LEU A CD1 1 
ATOM   1353 C CD2 . LEU A 1 207 ? 16.11300 9.50700   160.18800 1.000 5.62000  ? 207 LEU A CD2 1 
ATOM   1354 N N   . GLN A 1 208 ? 20.58700 11.09700  160.39300 1.000 5.27000  ? 208 GLN A N   1 
ATOM   1355 C CA  . GLN A 1 208 ? 21.33500 11.18200  159.14500 1.000 3.92000  ? 208 GLN A CA  1 
ATOM   1356 C C   . GLN A 1 208 ? 21.22500 9.85700   158.40400 1.000 4.65000  ? 208 GLN A C   1 
ATOM   1357 O O   . GLN A 1 208 ? 21.28900 8.78400   159.01700 1.000 5.20000  ? 208 GLN A O   1 
ATOM   1358 C CB  . GLN A 1 208 ? 22.82000 11.55900  159.39800 1.000 4.17000  ? 208 GLN A CB  1 
ATOM   1359 C CG  . GLN A 1 208 ? 23.65300 10.48300  160.08500 1.000 5.55000  ? 208 GLN A CG  1 
ATOM   1360 C CD  . GLN A 1 208 ? 25.12500 10.87000  160.18100 1.000 6.69000  ? 208 GLN A CD  1 
ATOM   1361 O OE1 . GLN A 1 208 ? 25.53200 11.92800  159.69700 1.000 7.59000  ? 208 GLN A OE1 1 
ATOM   1362 N NE2 . GLN A 1 208 ? 25.92500 10.01100  160.79000 1.000 5.87000  ? 208 GLN A NE2 1 
ATOM   1363 N N   . VAL A 1 209 ? 21.02500 9.94200   157.08700 1.000 4.11000  ? 209 VAL A N   1 
ATOM   1364 C CA  . VAL A 1 209 ? 20.76200 8.78600   156.23000 1.000 3.42000  ? 209 VAL A CA  1 
ATOM   1365 C C   . VAL A 1 209 ? 21.69900 8.80700   155.02400 1.000 4.24000  ? 209 VAL A C   1 
ATOM   1366 O O   . VAL A 1 209 ? 21.27300 9.14900   153.90800 1.000 4.58000  ? 209 VAL A O   1 
ATOM   1367 C CB  . VAL A 1 209 ? 19.29000 8.74600   155.77500 1.000 3.98000  ? 209 VAL A CB  1 
ATOM   1368 C CG1 . VAL A 1 209 ? 18.97100 7.40800   155.12000 1.000 4.53000  ? 209 VAL A CG1 1 
ATOM   1369 C CG2 . VAL A 1 209 ? 18.35200 8.97300   156.96700 1.000 4.50000  ? 209 VAL A CG2 1 
ATOM   1370 N N   . PRO A 1 210 ? 22.97200 8.43800   155.18600 1.000 4.51000  ? 210 PRO A N   1 
ATOM   1371 C CA  . PRO A 1 210 ? 23.86500 8.30900   154.02000 1.000 4.73000  ? 210 PRO A CA  1 
ATOM   1372 C C   . PRO A 1 210 ? 23.57600 7.02600   153.24700 1.000 5.88000  ? 210 PRO A C   1 
ATOM   1373 O O   . PRO A 1 210 ? 23.64800 5.92200   153.79200 1.000 6.83000  ? 210 PRO A O   1 
ATOM   1374 C CB  . PRO A 1 210 ? 25.26600 8.29100   154.64600 1.000 4.75000  ? 210 PRO A CB  1 
ATOM   1375 C CG  . PRO A 1 210 ? 25.04300 7.74400   156.03400 1.000 6.16000  ? 210 PRO A CG  1 
ATOM   1376 C CD  . PRO A 1 210 ? 23.67800 8.23200   156.46500 1.000 4.98000  ? 210 PRO A CD  1 
ATOM   1377 N N   . ILE A 1 211 ? 23.26100 7.17400   151.95900 1.000 5.55000  ? 211 ILE A N   1 
ATOM   1378 C CA  . ILE A 1 211 ? 22.81300 6.07200   151.11300 1.000 5.85000  ? 211 ILE A CA  1 
ATOM   1379 C C   . ILE A 1 211 ? 23.89800 5.78500   150.08300 1.000 6.74000  ? 211 ILE A C   1 
ATOM   1380 O O   . ILE A 1 211 ? 24.33100 6.69700   149.36900 1.000 6.68000  ? 211 ILE A O   1 
ATOM   1381 C CB  . ILE A 1 211 ? 21.47800 6.42400   150.43300 1.000 6.81000  ? 211 ILE A CB  1 
ATOM   1382 C CG1 . ILE A 1 211 ? 20.41100 6.61600   151.51400 1.000 6.58000  ? 211 ILE A CG1 1 
ATOM   1383 C CG2 . ILE A 1 211 ? 21.05500 5.33500   149.47900 1.000 7.27000  ? 211 ILE A CG2 1 
ATOM   1384 C CD1 . ILE A 1 211 ? 19.12100 7.21200   150.99400 1.000 7.85000  ? 211 ILE A CD1 1 
ATOM   1385 N N   . PHE A 1 212 ? 24.31300 4.50700   149.98800 1.000 4.75000  ? 212 PHE A N   1 
ATOM   1386 C CA  . PHE A 1 212 ? 25.54400 4.05700   149.32100 1.000 6.31000  ? 212 PHE A CA  1 
ATOM   1387 C C   . PHE A 1 212 ? 26.57400 5.18500   149.28200 1.000 6.95000  ? 212 PHE A C   1 
ATOM   1388 O O   . PHE A 1 212 ? 26.98600 5.64000   148.20100 1.000 7.38000  ? 212 PHE A O   1 
ATOM   1389 C CB  . PHE A 1 212 ? 25.30500 3.46800   147.90700 1.000 6.27000  ? 212 PHE A CB  1 
ATOM   1390 C CG  . PHE A 1 212 ? 24.15700 4.06800   147.12900 1.000 8.10000  ? 212 PHE A CG  1 
ATOM   1391 C CD1 . PHE A 1 212 ? 24.34500 5.20800   146.35500 1.000 8.74000  ? 212 PHE A CD1 1 
ATOM   1392 C CD2 . PHE A 1 212 ? 22.91900 3.44100   147.09700 1.000 8.15000  ? 212 PHE A CD2 1 
ATOM   1393 C CE1 . PHE A 1 212 ? 23.29300 5.74600   145.59800 1.000 8.66000  ? 212 PHE A CE1 1 
ATOM   1394 C CE2 . PHE A 1 212 ? 21.85700 3.97700   146.35800 1.000 6.91000  ? 212 PHE A CE2 1 
ATOM   1395 C CZ  . PHE A 1 212 ? 22.04400 5.13500   145.61400 1.000 9.35000  ? 212 PHE A CZ  1 
ATOM   1396 N N   . PRO A 1 213 ? 27.02600 5.63800   150.44700 1.000 6.36000  ? 213 PRO A N   1 
ATOM   1397 C CA  . PRO A 1 213 ? 27.90500 6.80800   150.51300 1.000 5.68000  ? 213 PRO A CA  1 
ATOM   1398 C C   . PRO A 1 213 ? 29.37100 6.46600   150.28700 1.000 10.60000 ? 213 PRO A C   1 
ATOM   1399 O O   . PRO A 1 213 ? 29.82000 5.33500   150.49200 1.000 8.86000  ? 213 PRO A O   1 
ATOM   1400 C CB  . PRO A 1 213 ? 27.70400 7.29800   151.95000 1.000 5.83000  ? 213 PRO A CB  1 
ATOM   1401 C CG  . PRO A 1 213 ? 27.54100 5.99400   152.71900 1.000 8.42000  ? 213 PRO A CG  1 
ATOM   1402 C CD  . PRO A 1 213 ? 26.74000 5.09000   151.78800 1.000 5.54000  ? 213 PRO A CD  1 
ATOM   1403 N N   . LEU A 1 214 ? 30.12700 7.49500   149.89200 1.000 7.06000  ? 214 LEU A N   1 
ATOM   1404 C CA  . LEU A 1 214 ? 31.58600 7.47400   149.96100 1.000 7.98000  ? 214 LEU A CA  1 
ATOM   1405 C C   . LEU A 1 214 ? 31.99200 8.11000   151.28700 1.000 7.94000  ? 214 LEU A C   1 
ATOM   1406 O O   . LEU A 1 214 ? 31.90300 9.33100   151.44800 1.000 9.38000  ? 214 LEU A O   1 
ATOM   1407 C CB  . LEU A 1 214 ? 32.20600 8.21500   148.77700 1.000 10.11000 ? 214 LEU A CB  1 
ATOM   1408 C CG  . LEU A 1 214 ? 33.67500 7.91800   148.43000 1.000 9.92000  ? 214 LEU A CG  1 
ATOM   1409 C CD1 . LEU A 1 214 ? 34.65900 8.44700   149.46200 1.000 20.54000 ? 214 LEU A CD1 1 
ATOM   1410 C CD2 . LEU A 1 214 ? 33.91100 6.42200   148.17900 1.000 14.28000 ? 214 LEU A CD2 1 
ATOM   1411 N N   . VAL A 1 215 ? 32.43600 7.28700   152.23200 1.000 7.28000  ? 215 VAL A N   1 
ATOM   1412 C CA  . VAL A 1 215 ? 32.87900 7.74800   153.54100 1.000 8.07000  ? 215 VAL A CA  1 
ATOM   1413 C C   . VAL A 1 215 ? 34.37400 7.51200   153.72600 1.000 10.84000 ? 215 VAL A C   1 
ATOM   1414 O O   . VAL A 1 215 ? 35.12900 8.44200   154.02700 1.000 7.36000  ? 215 VAL A O   1 
ATOM   1415 C CB  . VAL A 1 215 ? 32.06300 7.07400   154.66500 1.000 8.72000  ? 215 VAL A CB  1 
ATOM   1416 C CG1 . VAL A 1 215 ? 32.51000 7.58600   156.03500 1.000 6.03000  ? 215 VAL A CG1 1 
ATOM   1417 C CG2 . VAL A 1 215 ? 30.58200 7.34500   154.45300 1.000 8.17000  ? 215 VAL A CG2 1 
ATOM   1418 N N   . ALA A 1 216 ? 34.81900 6.27200   153.53300 1.000 8.16000  ? 216 ALA A N   1 
ATOM   1419 C CA  . ALA A 1 216 ? 36.23400 5.93700   153.45900 1.000 8.39000  ? 216 ALA A CA  1 
ATOM   1420 C C   . ALA A 1 216 ? 36.68200 5.83600   152.00500 1.000 11.81000 ? 216 ALA A C   1 
ATOM   1421 O O   . ALA A 1 216 ? 35.90700 5.46000   151.12300 1.000 10.53000 ? 216 ALA A O   1 
ATOM   1422 C CB  . ALA A 1 216 ? 36.52600 4.61500   154.17100 1.000 9.04000  ? 216 ALA A CB  1 
ATOM   1423 N N   . ASP A 1 217 ? 37.95100 6.16600   151.76900 1.000 10.29000 ? 217 ASP A N   1 
ATOM   1424 C CA  . ASP A 1 217 ? 38.55900 5.97100   150.45600 1.000 12.16000 ? 217 ASP A CA  1 
ATOM   1425 C C   . ASP A 1 217 ? 38.34300 4.53500   149.99400 1.000 12.56000 ? 217 ASP A C   1 
ATOM   1426 O O   . ASP A 1 217 ? 38.56100 3.58600   150.75300 1.000 14.78000 ? 217 ASP A O   1 
ATOM   1427 C CB  . ASP A 1 217 ? 40.05400 6.29200   150.54400 1.000 15.49000 ? 217 ASP A CB  1 
ATOM   1428 C CG  . ASP A 1 217 ? 40.72600 6.39800   149.18200 1.000 26.02000 ? 217 ASP A CG  1 
ATOM   1429 O OD1 . ASP A 1 217 ? 40.09700 6.06700   148.15700 1.000 21.11000 ? 217 ASP A OD1 1 
ATOM   1430 O OD2 . ASP A 1 217 ? 41.90300 6.81700   149.14700 1.000 24.55000 ? 217 ASP A OD2 1 
ATOM   1431 N N   . ALA A 1 218 ? 37.87200 4.37400   148.75900 1.000 11.43000 ? 218 ALA A N   1 
ATOM   1432 C CA  . ALA A 1 218 ? 37.48900 3.05600   148.27100 1.000 13.18000 ? 218 ALA A CA  1 
ATOM   1433 C C   . ALA A 1 218 ? 38.57900 2.35800   147.45900 1.000 17.23000 ? 218 ALA A C   1 
ATOM   1434 O O   . ALA A 1 218 ? 38.37100 1.21400   147.04500 1.000 15.04000 ? 218 ALA A O   1 
ATOM   1435 C CB  . ALA A 1 218 ? 36.21300 3.16400   147.42700 1.000 12.68000 ? 218 ALA A CB  1 
ATOM   1436 N N   . VAL A 1 219 ? 39.74800 2.98900   147.27600 1.000 18.74000 ? 219 VAL A N   1 
ATOM   1437 C CA  . VAL A 1 219 ? 40.65600 2.63300   146.17800 1.000 24.72000 ? 219 VAL A CA  1 
ATOM   1438 C C   . VAL A 1 219 ? 41.13000 1.18400   146.26400 1.000 26.81000 ? 219 VAL A C   1 
ATOM   1439 O O   . VAL A 1 219 ? 41.23000 0.49300   145.24000 1.000 34.35000 ? 219 VAL A O   1 
ATOM   1440 C CB  . VAL A 1 219 ? 41.85300 3.60200   146.12700 1.000 23.81000 ? 219 VAL A CB  1 
ATOM   1441 C CG1 . VAL A 1 219 ? 41.43200 4.94300   145.53100 1.000 31.01000 ? 219 VAL A CG1 1 
ATOM   1442 C CG2 . VAL A 1 219 ? 42.48300 3.76400   147.51700 1.000 30.77000 ? 219 VAL A CG2 1 
ATOM   1443 N N   . SER A 1 220 ? 41.46800 0.70900   147.46000 1.000 24.17000 ? 220 SER A N   1 
ATOM   1444 C CA  . SER A 1 220 ? 42.02200 -0.63200  147.60500 1.000 24.37000 ? 220 SER A CA  1 
ATOM   1445 C C   . SER A 1 220 ? 41.06500 -1.58500  148.31100 1.000 21.31000 ? 220 SER A C   1 
ATOM   1446 O O   . SER A 1 220 ? 41.49400 -2.61900  148.84000 1.000 18.13000 ? 220 SER A O   1 
ATOM   1447 C CB  . SER A 1 220 ? 43.36300 -0.57500  148.34300 1.000 30.51000 ? 220 SER A CB  1 
ATOM   1448 O OG  . SER A 1 220 ? 44.21400 0.39800   147.75500 1.000 33.78000 ? 220 SER A OG  1 
ATOM   1449 N N   . SER A 1 221 ? 39.77400 -1.27400  148.30900 1.000 17.22000 ? 221 SER A N   1 
ATOM   1450 C CA  . SER A 1 221 ? 38.81400 -2.11900  149.00100 1.000 17.11000 ? 221 SER A CA  1 
ATOM   1451 C C   . SER A 1 221 ? 38.51800 -3.37800  148.19500 1.000 14.32000 ? 221 SER A C   1 
ATOM   1452 O O   . SER A 1 221 ? 38.70700 -3.42800  146.97700 1.000 14.03000 ? 221 SER A O   1 
ATOM   1453 C CB  . SER A 1 221 ? 37.51700 -1.35700  149.25200 1.000 14.77000 ? 221 SER A CB  1 
ATOM   1454 O OG  . SER A 1 221 ? 36.96000 -0.94000  148.01600 1.000 14.43000 ? 221 SER A OG  1 
ATOM   1455 N N   . GLU A 1 222 ? 38.01500 -4.39800  148.89200 1.000 15.67000 ? 222 GLU A N   1 
ATOM   1456 C CA  . GLU A 1 222 ? 37.62100 -5.62200  148.20100 1.000 16.83000 ? 222 GLU A CA  1 
ATOM   1457 C C   . GLU A 1 222 ? 36.42800 -5.39500  147.28000 1.000 14.49000 ? 222 GLU A C   1 
ATOM   1458 O O   . GLU A 1 222 ? 36.35000 -5.99700  146.20500 1.000 12.07000 ? 222 GLU A O   1 
ATOM   1459 C CB  . GLU A 1 222 ? 37.30300 -6.72300  149.20900 1.000 20.07000 ? 222 GLU A CB  1 
ATOM   1460 C CG  . GLU A 1 222 ? 38.46700 -7.08300  150.10200 1.000 26.24000 ? 222 GLU A CG  1 
ATOM   1461 C CD  . GLU A 1 222 ? 38.04000 -7.93900  151.27600 1.000 43.74000 ? 222 GLU A CD  1 
ATOM   1462 O OE1 . GLU A 1 222 ? 36.96000 -8.56700  151.18800 1.000 47.88000 ? 222 GLU A OE1 1 
ATOM   1463 O OE2 . GLU A 1 222 ? 38.77400 -7.97200  152.28900 1.000 48.48000 ? 222 GLU A OE2 1 
ATOM   1464 N N   . SER A 1 223 ? 35.46800 -4.56000  147.68700 1.000 11.77000 ? 223 SER A N   1 
ATOM   1465 C CA  . SER A 1 223 ? 34.31700 -4.33600  146.81600 1.000 9.75000  ? 223 SER A CA  1 
ATOM   1466 C C   . SER A 1 223 ? 34.72400 -3.59600  145.54600 1.000 8.90000  ? 223 SER A C   1 
ATOM   1467 O O   . SER A 1 223 ? 34.13900 -3.82100  144.48100 1.000 9.47000  ? 223 SER A O   1 
ATOM   1468 C CB  . SER A 1 223 ? 33.21300 -3.57400  147.56600 1.000 10.99000 ? 223 SER A CB  1 
ATOM   1469 O OG  . SER A 1 223 ? 33.68500 -2.34400  148.08800 1.000 8.23000  ? 223 SER A OG  1 
ATOM   1470 N N   . MET A 1 224 ? 35.72000 -2.71300  145.63500 1.000 8.19000  ? 224 MET A N   1 
ATOM   1471 C CA  . MET A 1 224 ? 36.20100 -2.03900  144.43400 1.000 10.60000 ? 224 MET A CA  1 
ATOM   1472 C C   . MET A 1 224 ? 36.79700 -3.04500  143.45700 1.000 13.19000 ? 224 MET A C   1 
ATOM   1473 O O   . MET A 1 224 ? 36.54300 -2.97500  142.25300 1.000 13.91000 ? 224 MET A O   1 
ATOM   1474 C CB  . MET A 1 224 ? 37.22400 -0.96600  144.81300 1.000 12.70000 ? 224 MET A CB  1 
ATOM   1475 C CG  . MET A 1 224 ? 37.76700 -0.15600  143.64500 1.000 18.57000 ? 224 MET A CG  1 
ATOM   1476 S SD  . MET A 1 224 ? 36.53600 0.85800   142.79800 1.000 23.88000 ? 224 MET A SD  1 
ATOM   1477 C CE  . MET A 1 224 ? 36.05000 2.00800   144.06400 1.000 22.96000 ? 224 MET A CE  1 
ATOM   1478 N N   . ALA A 1 225 ? 37.57800 -4.00300  143.96100 1.000 12.28000 ? 225 ALA A N   1 
ATOM   1479 C CA  . ALA A 1 225 ? 38.14900 -5.01400  143.07600 1.000 14.39000 ? 225 ALA A CA  1 
ATOM   1480 C C   . ALA A 1 225 ? 37.07700 -5.92200  142.48200 1.000 15.34000 ? 225 ALA A C   1 
ATOM   1481 O O   . ALA A 1 225 ? 37.22200 -6.38200  141.34500 1.000 18.50000 ? 225 ALA A O   1 
ATOM   1482 C CB  . ALA A 1 225 ? 39.19200 -5.83900  143.83200 1.000 15.12000 ? 225 ALA A CB  1 
ATOM   1483 N N   . ALA A 1 226 ? 35.99000 -6.17000  143.21500 1.000 13.15000 ? 226 ALA A N   1 
ATOM   1484 C CA  . ALA A 1 226 ? 34.98400 -7.13100  142.77100 1.000 11.42000 ? 226 ALA A CA  1 
ATOM   1485 C C   . ALA A 1 226 ? 33.97500 -6.53500  141.79800 1.000 12.84000 ? 226 ALA A C   1 
ATOM   1486 O O   . ALA A 1 226 ? 33.48600 -7.24600  140.91100 1.000 13.36000 ? 226 ALA A O   1 
ATOM   1487 C CB  . ALA A 1 226 ? 34.23100 -7.70100  143.97900 1.000 11.29000 ? 226 ALA A CB  1 
ATOM   1488 N N   . PHE A 1 227 ? 33.62800 -5.25200  141.95300 1.000 10.64000 ? 227 PHE A N   1 
ATOM   1489 C CA  . PHE A 1 227 ? 32.47100 -4.70600  141.25200 1.000 10.64000 ? 227 PHE A CA  1 
ATOM   1490 C C   . PHE A 1 227 ? 32.80200 -3.47100  140.42100 1.000 11.36000 ? 227 PHE A C   1 
ATOM   1491 O O   . PHE A 1 227 ? 31.89100 -2.71000  140.08100 1.000 14.63000 ? 227 PHE A O   1 
ATOM   1492 C CB  . PHE A 1 227 ? 31.34900 -4.37100  142.24000 1.000 11.44000 ? 227 PHE A CB  1 
ATOM   1493 C CG  . PHE A 1 227 ? 30.96300 -5.50600  143.13500 1.000 9.31000  ? 227 PHE A CG  1 
ATOM   1494 C CD1 . PHE A 1 227 ? 30.40200 -6.66600  142.61400 1.000 14.00000 ? 227 PHE A CD1 1 
ATOM   1495 C CD2 . PHE A 1 227 ? 31.15100 -5.41500  144.50200 1.000 10.31000 ? 227 PHE A CD2 1 
ATOM   1496 C CE1 . PHE A 1 227 ? 30.04600 -7.71200  143.44400 1.000 12.68000 ? 227 PHE A CE1 1 
ATOM   1497 C CE2 . PHE A 1 227 ? 30.79300 -6.46100  145.34100 1.000 13.32000 ? 227 PHE A CE2 1 
ATOM   1498 C CZ  . PHE A 1 227 ? 30.24200 -7.61400  144.80400 1.000 12.24000 ? 227 PHE A CZ  1 
ATOM   1499 N N   . SER A 1 228 ? 34.06800 -3.27300  140.04700 1.000 12.52000 ? 228 SER A N   1 
ATOM   1500 C CA  . SER A 1 228 ? 34.45600 -2.03100  139.38400 1.000 16.95000 ? 228 SER A CA  1 
ATOM   1501 C C   . SER A 1 228 ? 34.09500 -1.98600  137.90500 1.000 18.56000 ? 228 SER A C   1 
ATOM   1502 O O   . SER A 1 228 ? 34.26000 -0.92700  137.29100 1.000 13.58000 ? 228 SER A O   1 
ATOM   1503 C CB  . SER A 1 228 ? 35.96300 -1.78200  139.52900 1.000 17.84000 ? 228 SER A CB  1 
ATOM   1504 O OG  . SER A 1 228 ? 36.70600 -2.89900  139.08500 1.000 30.88000 ? 228 SER A OG  1 
ATOM   1505 N N   . GLU A 1 229 ? 33.61700 -3.08600  137.31800 1.000 12.39000 ? 229 GLU A N   1 
ATOM   1506 C CA  . GLU A 1 229 ? 33.06600 -3.06600  135.96900 1.000 14.67000 ? 229 GLU A CA  1 
ATOM   1507 C C   . GLU A 1 229 ? 31.78300 -3.88600  135.93300 1.000 13.28000 ? 229 GLU A C   1 
ATOM   1508 O O   . GLU A 1 229 ? 31.65000 -4.88300  136.64400 1.000 13.33000 ? 229 GLU A O   1 
ATOM   1509 C CB  . GLU A 1 229 ? 34.05700 -3.61600  134.92600 1.000 18.34000 ? 229 GLU A CB  1 
ATOM   1510 C CG  . GLU A 1 229 ? 35.39300 -2.87100  134.84300 1.000 22.33000 ? 229 GLU A CG  1 
ATOM   1511 C CD  . GLU A 1 229 ? 35.25600 -1.40300  134.43800 1.000 24.51000 ? 229 GLU A CD  1 
ATOM   1512 O OE1 . GLU A 1 229 ? 36.15400 -0.61300  134.80300 1.000 24.43000 ? 229 GLU A OE1 1 
ATOM   1513 O OE2 . GLU A 1 229 ? 34.26700 -1.03400  133.76200 1.000 23.04000 ? 229 GLU A OE2 1 
ATOM   1514 N N   . GLY A 1 230 ? 30.83100 -3.44900  135.10400 1.000 13.08000 ? 230 GLY A N   1 
ATOM   1515 C CA  . GLY A 1 230 ? 29.63400 -4.22300  134.85200 1.000 13.91000 ? 230 GLY A CA  1 
ATOM   1516 C C   . GLY A 1 230 ? 28.48200 -3.99000  135.80600 1.000 13.43000 ? 230 GLY A C   1 
ATOM   1517 O O   . GLY A 1 230 ? 27.42900 -4.61800  135.63600 1.000 13.89000 ? 230 GLY A O   1 
ATOM   1518 N N   . TYR A 1 231 ? 28.63400 -3.10300  136.79100 1.000 10.59000 ? 231 TYR A N   1 
ATOM   1519 C CA  . TYR A 1 231 ? 27.60200 -2.86400  137.79500 1.000 8.47000  ? 231 TYR A CA  1 
ATOM   1520 C C   . TYR A 1 231 ? 27.27200 -1.38000  137.89400 1.000 13.58000 ? 231 TYR A C   1 
ATOM   1521 O O   . TYR A 1 231 ? 27.07500 -0.84400  138.99100 1.000 11.70000 ? 231 TYR A O   1 
ATOM   1522 C CB  . TYR A 1 231 ? 28.03100 -3.41900  139.15000 1.000 10.56000 ? 231 TYR A CB  1 
ATOM   1523 C CG  . TYR A 1 231 ? 28.17100 -4.92400  139.16000 1.000 11.22000 ? 231 TYR A CG  1 
ATOM   1524 C CD1 . TYR A 1 231 ? 27.06500 -5.74400  139.35200 1.000 8.83000  ? 231 TYR A CD1 1 
ATOM   1525 C CD2 . TYR A 1 231 ? 29.40800 -5.52300  138.96800 1.000 13.98000 ? 231 TYR A CD2 1 
ATOM   1526 C CE1 . TYR A 1 231 ? 27.19500 -7.12100  139.35100 1.000 13.32000 ? 231 TYR A CE1 1 
ATOM   1527 C CE2 . TYR A 1 231 ? 29.54800 -6.89900  138.97300 1.000 13.14000 ? 231 TYR A CE2 1 
ATOM   1528 C CZ  . TYR A 1 231 ? 28.44100 -7.68900  139.16300 1.000 14.82000 ? 231 TYR A CZ  1 
ATOM   1529 O OH  . TYR A 1 231 ? 28.58700 -9.05500  139.17600 1.000 14.74000 ? 231 TYR A OH  1 
ATOM   1530 N N   . LEU A 1 232 ? 27.21600 -0.70600  136.73600 1.000 9.88000  ? 232 LEU A N   1 
ATOM   1531 C CA  . LEU A 1 232 ? 26.79700 0.68900   136.56500 1.000 9.69000  ? 232 LEU A CA  1 
ATOM   1532 C C   . LEU A 1 232 ? 27.89100 1.67200   136.96800 1.000 14.73000 ? 232 LEU A C   1 
ATOM   1533 O O   . LEU A 1 232 ? 28.38000 2.43200   136.12400 1.000 13.85000 ? 232 LEU A O   1 
ATOM   1534 C CB  . LEU A 1 232 ? 25.50500 0.99600   137.34100 1.000 12.73000 ? 232 LEU A CB  1 
ATOM   1535 C CG  . LEU A 1 232 ? 24.22200 0.31500   136.87100 1.000 15.28000 ? 232 LEU A CG  1 
ATOM   1536 C CD1 . LEU A 1 232 ? 23.01800 0.84300   137.64400 1.000 18.32000 ? 232 LEU A CD1 1 
ATOM   1537 C CD2 . LEU A 1 232 ? 24.02800 0.50000   135.36600 1.000 17.99000 ? 232 LEU A CD2 1 
ATOM   1538 N N   . LEU A 1 233 ? 28.27700 1.67900   138.24200 1.000 12.08000 ? 233 LEU A N   1 
ATOM   1539 C CA  . LEU A 1 233 ? 29.34400 2.55400   138.73900 1.000 9.79000  ? 233 LEU A CA  1 
ATOM   1540 C C   . LEU A 1 233 ? 30.69100 1.89400   138.47300 1.000 12.08000 ? 233 LEU A C   1 
ATOM   1541 O O   . LEU A 1 233 ? 30.99500 0.85000   139.05500 1.000 12.37000 ? 233 LEU A O   1 
ATOM   1542 C CB  . LEU A 1 233 ? 29.16100 2.81100   140.23300 1.000 10.89000 ? 233 LEU A CB  1 
ATOM   1543 C CG  . LEU A 1 233 ? 30.27600 3.59700   140.92200 1.000 8.16000  ? 233 LEU A CG  1 
ATOM   1544 C CD1 . LEU A 1 233 ? 30.48000 4.92500   140.19900 1.000 11.93000 ? 233 LEU A CD1 1 
ATOM   1545 C CD2 . LEU A 1 233 ? 29.93100 3.82200   142.38800 1.000 9.43000  ? 233 LEU A CD2 1 
ATOM   1546 N N   . THR A 1 234 ? 31.50200 2.49800   137.61000 1.000 12.51000 ? 234 THR A N   1 
ATOM   1547 C CA  . THR A 1 234 ? 32.73000 1.88500   137.12600 1.000 14.59000 ? 234 THR A CA  1 
ATOM   1548 C C   . THR A 1 234 ? 33.96300 2.54700   137.72400 1.000 15.36000 ? 234 THR A C   1 
ATOM   1549 O O   . THR A 1 234 ? 33.91900 3.67200   138.23000 1.000 13.15000 ? 234 THR A O   1 
ATOM   1550 C CB  . THR A 1 234 ? 32.82000 1.96700   135.60300 1.000 14.73000 ? 234 THR A CB  1 
ATOM   1551 O OG1 . THR A 1 234 ? 32.86200 3.34400   135.20500 1.000 14.98000 ? 234 THR A OG1 1 
ATOM   1552 C CG2 . THR A 1 234 ? 31.62000 1.28300   134.95800 1.000 15.90000 ? 234 THR A CG2 1 
ATOM   1553 N N   . ALA A 1 235 ? 35.08700 1.82900   137.63400 1.000 16.29000 ? 235 ALA A N   1 
ATOM   1554 C CA  . ALA A 1 235 ? 36.36100 2.40000   138.05900 1.000 18.85000 ? 235 ALA A CA  1 
ATOM   1555 C C   . ALA A 1 235 ? 36.69500 3.66300   137.27100 1.000 15.11000 ? 235 ALA A C   1 
ATOM   1556 O O   . ALA A 1 235 ? 37.23500 4.62600   137.83100 1.000 16.72000 ? 235 ALA A O   1 
ATOM   1557 C CB  . ALA A 1 235 ? 37.47300 1.36000   137.91000 1.000 21.10000 ? 235 ALA A CB  1 
ATOM   1558 N N   . GLU A 1 236 ? 36.38700 3.67600   135.97000 1.000 14.68000 ? 236 GLU A N   1 
ATOM   1559 C CA  . GLU A 1 236 ? 36.64500 4.85700   135.14900 1.000 16.98000 ? 236 GLU A CA  1 
ATOM   1560 C C   . GLU A 1 236 ? 35.83400 6.04700   135.63600 1.000 17.39000 ? 236 GLU A C   1 
ATOM   1561 O O   . GLU A 1 236 ? 36.34400 7.17200   135.70900 1.000 13.28000 ? 236 GLU A O   1 
ATOM   1562 C CB  . GLU A 1 236 ? 36.31600 4.57700   133.68200 1.000 19.75000 ? 236 GLU A CB  1 
ATOM   1563 C CG  . GLU A 1 236 ? 37.31900 3.68500   132.97100 1.000 24.03000 ? 236 GLU A CG  1 
ATOM   1564 C CD  . GLU A 1 236 ? 37.10500 2.21000   133.27000 1.000 31.66000 ? 236 GLU A CD  1 
ATOM   1565 O OE1 . GLU A 1 236 ? 36.02800 1.85300   133.80800 1.000 23.34000 ? 236 GLU A OE1 1 
ATOM   1566 O OE2 . GLU A 1 236 ? 38.01200 1.40900   132.95300 1.000 34.56000 ? 236 GLU A OE2 1 
ATOM   1567 N N   . THR A 1 237 ? 34.56400 5.81800   135.96800 1.000 15.11000 ? 237 THR A N   1 
ATOM   1568 C CA  . THR A 1 237 ? 33.74100 6.89900   136.50100 1.000 11.12000 ? 237 THR A CA  1 
ATOM   1569 C C   . THR A 1 237 ? 34.28900 7.39300   137.83300 1.000 11.96000 ? 237 THR A C   1 
ATOM   1570 O O   . THR A 1 237 ? 34.38400 8.60500   138.05800 1.000 12.18000 ? 237 THR A O   1 
ATOM   1571 C CB  . THR A 1 237 ? 32.29500 6.42600   136.63200 1.000 12.25000 ? 237 THR A CB  1 
ATOM   1572 O OG1 . THR A 1 237 ? 31.73600 6.27900   135.32600 1.000 15.28000 ? 237 THR A OG1 1 
ATOM   1573 C CG2 . THR A 1 237 ? 31.46600 7.42500   137.39600 1.000 13.69000 ? 237 THR A CG2 1 
ATOM   1574 N N   . MET A 1 238 ? 34.67000 6.47000   138.72500 1.000 10.60000 ? 238 MET A N   1 
ATOM   1575 C CA  . MET A 1 238 ? 35.21900 6.87400   140.01600 1.000 16.11000 ? 238 MET A CA  1 
ATOM   1576 C C   . MET A 1 238 ? 36.47300 7.71800   139.83400 1.000 14.00000 ? 238 MET A C   1 
ATOM   1577 O O   . MET A 1 238 ? 36.67500 8.70900   140.54700 1.000 11.75000 ? 238 MET A O   1 
ATOM   1578 C CB  . MET A 1 238 ? 35.53100 5.64600   140.87900 1.000 16.44000 ? 238 MET A CB  1 
ATOM   1579 C CG  . MET A 1 238 ? 34.31800 4.97200   141.52300 1.000 20.04000 ? 238 MET A CG  1 
ATOM   1580 S SD  . MET A 1 238 ? 33.42300 6.03500   142.68700 1.000 29.30000 ? 238 MET A SD  1 
ATOM   1581 C CE  . MET A 1 238 ? 34.65300 6.42100   143.94300 1.000 26.12000 ? 238 MET A CE  1 
ATOM   1582 N N   . ALA A 1 239 ? 37.32900 7.33800   138.87900 1.000 11.92000 ? 239 ALA A N   1 
ATOM   1583 C CA  . ALA A 1 239 ? 38.56000 8.08700   138.65300 1.000 14.15000 ? 239 ALA A CA  1 
ATOM   1584 C C   . ALA A 1 239 ? 38.25800 9.46300   138.07600 1.000 13.63000 ? 239 ALA A C   1 
ATOM   1585 O O   . ALA A 1 239 ? 38.92400 10.45000  138.42100 1.000 12.27000 ? 239 ALA A O   1 
ATOM   1586 C CB  . ALA A 1 239 ? 39.48800 7.29800   137.72900 1.000 16.53000 ? 239 ALA A CB  1 
ATOM   1587 N N   . PHE A 1 240 ? 37.24800 9.54100   137.20200 1.000 9.32000  ? 240 PHE A N   1 
ATOM   1588 C CA  . PHE A 1 240 ? 36.80300 10.81800  136.65300 1.000 9.62000  ? 240 PHE A CA  1 
ATOM   1589 C C   . PHE A 1 240 ? 36.32800 11.75900  137.75400 1.000 11.72000 ? 240 PHE A C   1 
ATOM   1590 O O   . PHE A 1 240 ? 36.73800 12.92900  137.81400 1.000 9.45000  ? 240 PHE A O   1 
ATOM   1591 C CB  . PHE A 1 240 ? 35.69200 10.55700  135.63700 1.000 11.18000 ? 240 PHE A CB  1 
ATOM   1592 C CG  . PHE A 1 240 ? 34.95000 11.78700  135.19900 1.000 13.04000 ? 240 PHE A CG  1 
ATOM   1593 C CD1 . PHE A 1 240 ? 35.50400 12.64600  134.26100 1.000 13.52000 ? 240 PHE A CD1 1 
ATOM   1594 C CD2 . PHE A 1 240 ? 33.68100 12.06000  135.69300 1.000 11.06000 ? 240 PHE A CD2 1 
ATOM   1595 C CE1 . PHE A 1 240 ? 34.81800 13.77100  133.83600 1.000 14.64000 ? 240 PHE A CE1 1 
ATOM   1596 C CE2 . PHE A 1 240 ? 32.97800 13.18800  135.27600 1.000 13.08000 ? 240 PHE A CE2 1 
ATOM   1597 C CZ  . PHE A 1 240 ? 33.55200 14.04700  134.34100 1.000 13.78000 ? 240 PHE A CZ  1 
ATOM   1598 N N   . PHE A 1 241 ? 35.43300 11.27200  138.62000 1.000 10.02000 ? 241 PHE A N   1 
ATOM   1599 C CA  . PHE A 1 241 ? 34.95700 12.09300  139.73400 1.000 10.04000 ? 241 PHE A CA  1 
ATOM   1600 C C   . PHE A 1 241 ? 36.11000 12.50000  140.64000 1.000 9.33000  ? 241 PHE A C   1 
ATOM   1601 O O   . PHE A 1 241 ? 36.19300 13.65300  141.07700 1.000 9.06000  ? 241 PHE A O   1 
ATOM   1602 C CB  . PHE A 1 241 ? 33.92100 11.32500  140.55500 1.000 7.84000  ? 241 PHE A CB  1 
ATOM   1603 C CG  . PHE A 1 241 ? 32.60500 11.08500  139.85600 1.000 9.32000  ? 241 PHE A CG  1 
ATOM   1604 C CD1 . PHE A 1 241 ? 32.09900 11.97600  138.92700 1.000 8.84000  ? 241 PHE A CD1 1 
ATOM   1605 C CD2 . PHE A 1 241 ? 31.83900 9.96700   140.20000 1.000 10.67000 ? 241 PHE A CD2 1 
ATOM   1606 C CE1 . PHE A 1 241 ? 30.86300 11.74300  138.31700 1.000 8.06000  ? 241 PHE A CE1 1 
ATOM   1607 C CE2 . PHE A 1 241 ? 30.60400 9.74000   139.61000 1.000 10.03000 ? 241 PHE A CE2 1 
ATOM   1608 C CZ  . PHE A 1 241 ? 30.12100 10.61800  138.66100 1.000 12.44000 ? 241 PHE A CZ  1 
ATOM   1609 N N   . ASP A 1 242 ? 36.98600 11.54000  140.95100 1.000 10.42000 ? 242 ASP A N   1 
ATOM   1610 C CA  . ASP A 1 242 ? 38.13800 11.76300  141.82000 1.000 14.97000 ? 242 ASP A CA  1 
ATOM   1611 C C   . ASP A 1 242 ? 38.99000 12.92200  141.31700 1.000 17.15000 ? 242 ASP A C   1 
ATOM   1612 O O   . ASP A 1 242 ? 39.34400 13.82500  142.08600 1.000 15.08000 ? 242 ASP A O   1 
ATOM   1613 C CB  . ASP A 1 242 ? 38.97200 10.48600  141.85800 1.000 18.39000 ? 242 ASP A CB  1 
ATOM   1614 C CG  . ASP A 1 242 ? 39.68600 10.26700  143.16400 1.000 33.16000 ? 242 ASP A CG  1 
ATOM   1615 O OD1 . ASP A 1 242 ? 39.90600 11.24800  143.90800 1.000 44.08000 ? 242 ASP A OD1 1 
ATOM   1616 O OD2 . ASP A 1 242 ? 40.04000 9.09800   143.43800 1.000 43.42000 ? 242 ASP A OD2 1 
ATOM   1617 N N   . ALA A 1 243 ? 39.33600 12.90800  140.02400 1.000 11.32000 ? 243 ALA A N   1 
ATOM   1618 C CA  . ALA A 1 243 ? 40.19900 13.94700  139.46500 1.000 12.42000 ? 243 ALA A CA  1 
ATOM   1619 C C   . ALA A 1 243 ? 39.50000 15.30200  139.43800 1.000 13.71000 ? 243 ALA A C   1 
ATOM   1620 O O   . ALA A 1 243 ? 40.13700 16.33300  139.67300 1.000 13.55000 ? 243 ALA A O   1 
ATOM   1621 C CB  . ALA A 1 243 ? 40.65000 13.55600  138.05500 1.000 12.24000 ? 243 ALA A CB  1 
ATOM   1622 N N   . ALA A 1 244 ? 38.19100 15.32500  139.16100 1.000 9.96000  ? 244 ALA A N   1 
ATOM   1623 C CA  . ALA A 1 244 ? 37.48100 16.60000  139.08600 1.000 10.21000 ? 244 ALA A CA  1 
ATOM   1624 C C   . ALA A 1 244 ? 37.34600 17.24500  140.46100 1.000 8.01000  ? 244 ALA A C   1 
ATOM   1625 O O   . ALA A 1 244 ? 37.52300 18.46200  140.60700 1.000 10.93000 ? 244 ALA A O   1 
ATOM   1626 C CB  . ALA A 1 244 ? 36.10100 16.40000  138.45900 1.000 8.89000  ? 244 ALA A CB  1 
ATOM   1627 N N   . TYR A 1 245 ? 37.02500 16.44600  141.47600 1.000 7.92000  ? 245 TYR A N   1 
ATOM   1628 C CA  . TYR A 1 245 ? 36.76800 16.98100  142.80800 1.000 9.10000  ? 245 TYR A CA  1 
ATOM   1629 C C   . TYR A 1 245 ? 38.06100 17.30500  143.54600 1.000 9.82000  ? 245 TYR A C   1 
ATOM   1630 O O   . TYR A 1 245 ? 38.16600 18.35800  144.17700 1.000 7.93000  ? 245 TYR A O   1 
ATOM   1631 C CB  . TYR A 1 245 ? 35.93400 15.97700  143.59500 1.000 7.77000  ? 245 TYR A CB  1 
ATOM   1632 C CG  . TYR A 1 245 ? 35.31100 16.49600  144.87600 1.000 8.87000  ? 245 TYR A CG  1 
ATOM   1633 C CD1 . TYR A 1 245 ? 34.53100 17.64800  144.88700 1.000 8.17000  ? 245 TYR A CD1 1 
ATOM   1634 C CD2 . TYR A 1 245 ? 35.48400 15.80400  146.06600 1.000 8.59000  ? 245 TYR A CD2 1 
ATOM   1635 C CE1 . TYR A 1 245 ? 33.94000 18.09900  146.06900 1.000 8.26000  ? 245 TYR A CE1 1 
ATOM   1636 C CE2 . TYR A 1 245 ? 34.90700 16.24200  147.24700 1.000 7.69000  ? 245 TYR A CE2 1 
ATOM   1637 C CZ  . TYR A 1 245 ? 34.14000 17.38700  147.24200 1.000 7.74000  ? 245 TYR A CZ  1 
ATOM   1638 O OH  . TYR A 1 245 ? 33.55300 17.79300  148.41500 1.000 7.03000  ? 245 TYR A OH  1 
ATOM   1639 N N   . GLY A 1 246 ? 39.04700 16.41600  143.49100 1.000 9.43000  ? 246 GLY A N   1 
ATOM   1640 C CA  . GLY A 1 246 ? 40.34900 16.71500  144.07000 1.000 10.67000 ? 246 GLY A CA  1 
ATOM   1641 C C   . GLY A 1 246 ? 40.38800 16.80100  145.58400 1.000 12.46000 ? 246 GLY A C   1 
ATOM   1642 O O   . GLY A 1 246 ? 41.07000 17.67600  146.13400 1.000 15.00000 ? 246 GLY A O   1 
ATOM   1643 N N   . ALA A 1 247 ? 39.69800 15.90200  146.27500 1.000 10.62000 ? 247 ALA A N   1 
ATOM   1644 C CA  . ALA A 1 247 ? 39.67500 15.93900  147.73200 1.000 14.30000 ? 247 ALA A CA  1 
ATOM   1645 C C   . ALA A 1 247 ? 40.97800 15.40000  148.31000 1.000 13.91000 ? 247 ALA A C   1 
ATOM   1646 O O   . ALA A 1 247 ? 41.49800 14.37900  147.86600 1.000 12.59000 ? 247 ALA A O   1 
ATOM   1647 C CB  . ALA A 1 247 ? 38.50200 15.12700  148.27700 1.000 12.86000 ? 247 ALA A CB  1 
ATOM   1648 N N   . ASP A 1 248 ? 41.47900 16.07400  149.33900 1.000 14.67000 ? 248 ASP A N   1 
ATOM   1649 C CA  . ASP A 1 248 ? 42.71000 15.63900  149.98400 1.000 19.75000 ? 248 ASP A CA  1 
ATOM   1650 C C   . ASP A 1 248 ? 42.46600 14.40600  150.84700 1.000 12.24000 ? 248 ASP A C   1 
ATOM   1651 O O   . ASP A 1 248 ? 41.52900 14.36200  151.64800 1.000 11.51000 ? 248 ASP A O   1 
ATOM   1652 C CB  . ASP A 1 248 ? 43.28800 16.77400  150.79900 1.000 27.99000 ? 248 ASP A CB  1 
ATOM   1653 C CG  . ASP A 1 248 ? 43.72900 17.90300  149.92200 1.000 34.94000 ? 248 ASP A CG  1 
ATOM   1654 O OD1 . ASP A 1 248 ? 44.82700 17.78300  149.32100 1.000 40.28000 ? 248 ASP A OD1 1 
ATOM   1655 O OD2 . ASP A 1 248 ? 42.94300 18.87200  149.78100 1.000 31.20000 ? 248 ASP A OD2 1 
ATOM   1656 N N   . ARG A 1 249 ? 43.32300 13.39900  150.66900 1.000 16.87000 ? 249 ARG A N   1 
ATOM   1657 C CA  . ARG A 1 249 ? 43.09300 12.08700  151.26500 1.000 18.21000 ? 249 ARG A CA  1 
ATOM   1658 C C   . ARG A 1 249 ? 43.09700 12.10200  152.78900 1.000 15.13000 ? 249 ARG A C   1 
ATOM   1659 O O   . ARG A 1 249 ? 42.47200 11.23100  153.40700 1.000 15.88000 ? 249 ARG A O   1 
ATOM   1660 C CB  . ARG A 1 249 ? 44.15200 11.10300  150.77200 1.000 20.81000 ? 249 ARG A CB  1 
ATOM   1661 C CG  . ARG A 1 249 ? 43.71100 10.24500  149.60600 1.000 27.28000 ? 249 ARG A CG  1 
ATOM   1662 C CD  . ARG A 1 249 ? 42.95700 11.03400  148.55100 1.000 27.51000 ? 249 ARG A CD  1 
ATOM   1663 N NE  . ARG A 1 249 ? 42.35700 10.12000  147.58600 1.000 43.66000 ? 249 ARG A NE  1 
ATOM   1664 C CZ  . ARG A 1 249 ? 41.61700 10.49400  146.54900 1.000 37.52000 ? 249 ARG A CZ  1 
ATOM   1665 N NH1 . ARG A 1 249 ? 41.36500 11.78300  146.33100 1.000 34.35000 ? 249 ARG A NH1 1 
ATOM   1666 N NH2 . ARG A 1 249 ? 41.12200 9.57000   145.73800 1.000 36.38000 ? 249 ARG A NH2 1 
ATOM   1667 N N   . SER A 1 250 ? 43.78100 13.04700  153.42200 1.000 12.99000 ? 250 SER A N   1 
ATOM   1668 C CA  . SER A 1 250 ? 43.81700 13.07800  154.87700 1.000 13.90000 ? 250 SER A CA  1 
ATOM   1669 C C   . SER A 1 250 ? 42.84900 14.08700  155.48400 1.000 11.72000 ? 250 SER A C   1 
ATOM   1670 O O   . SER A 1 250 ? 42.83900 14.25900  156.70800 1.000 13.84000 ? 250 SER A O   1 
ATOM   1671 C CB  . SER A 1 250 ? 45.24300 13.35500  155.35600 1.000 19.99000 ? 250 SER A CB  1 
ATOM   1672 O OG  . SER A 1 250 ? 45.69900 14.58600  154.84000 1.000 23.64000 ? 250 SER A OG  1 
ATOM   1673 N N   . ASP A 1 251 ? 42.01700 14.73500  154.67000 1.000 12.10000 ? 251 ASP A N   1 
ATOM   1674 C CA  . ASP A 1 251 ? 41.07800 15.73800  155.15600 1.000 14.03000 ? 251 ASP A CA  1 
ATOM   1675 C C   . ASP A 1 251 ? 39.75000 15.06700  155.48300 1.000 11.18000 ? 251 ASP A C   1 
ATOM   1676 O O   . ASP A 1 251 ? 39.12500 14.49400  154.57900 1.000 9.56000  ? 251 ASP A O   1 
ATOM   1677 C CB  . ASP A 1 251 ? 40.86300 16.81500  154.09900 1.000 14.07000 ? 251 ASP A CB  1 
ATOM   1678 C CG  . ASP A 1 251 ? 40.11000 18.03600  154.61600 1.000 16.63000 ? 251 ASP A CG  1 
ATOM   1679 O OD1 . ASP A 1 251 ? 39.35800 17.94800  155.61300 1.000 21.10000 ? 251 ASP A OD1 1 
ATOM   1680 O OD2 . ASP A 1 251 ? 40.27300 19.11500  153.99800 1.000 16.86000 ? 251 ASP A OD2 1 
ATOM   1681 N N   . PRO A 1 252 ? 39.28300 15.12400  156.73400 1.000 9.72000  ? 252 PRO A N   1 
ATOM   1682 C CA  . PRO A 1 252 ? 37.97100 14.53900  157.07800 1.000 9.46000  ? 252 PRO A CA  1 
ATOM   1683 C C   . PRO A 1 252 ? 36.80900 15.14600  156.31600 1.000 8.64000  ? 252 PRO A C   1 
ATOM   1684 O O   . PRO A 1 252 ? 35.75300 14.51000  156.22600 1.000 7.91000  ? 252 PRO A O   1 
ATOM   1685 C CB  . PRO A 1 252 ? 37.84100 14.82700  158.58100 1.000 10.74000 ? 252 PRO A CB  1 
ATOM   1686 C CG  . PRO A 1 252 ? 39.24300 15.05700  159.04500 1.000 11.46000 ? 252 PRO A CG  1 
ATOM   1687 C CD  . PRO A 1 252 ? 39.94400 15.71800  157.91100 1.000 10.92000 ? 252 PRO A CD  1 
ATOM   1688 N N   . ARG A 1 253 ? 36.95200 16.36800  155.79100 1.000 7.05000  ? 253 ARG A N   1 
ATOM   1689 C CA  . ARG A 1 253 ? 35.89100 16.93500  154.96700 1.000 5.56000  ? 253 ARG A CA  1 
ATOM   1690 C C   . ARG A 1 253 ? 35.83700 16.29200  153.58500 1.000 6.61000  ? 253 ARG A C   1 
ATOM   1691 O O   . ARG A 1 253 ? 34.83400 16.45200  152.88100 1.000 6.63000  ? 253 ARG A O   1 
ATOM   1692 C CB  . ARG A 1 253 ? 36.07400 18.45000  154.82500 1.000 9.25000  ? 253 ARG A CB  1 
ATOM   1693 C CG  . ARG A 1 253 ? 35.86300 19.25500  156.11500 1.000 13.88000 ? 253 ARG A CG  1 
ATOM   1694 C CD  . ARG A 1 253 ? 36.07000 20.76700  155.84200 1.000 21.86000 ? 253 ARG A CD  1 
ATOM   1695 N NE  . ARG A 1 253 ? 37.36500 21.04700  155.20900 1.000 24.43000 ? 253 ARG A NE  1 
ATOM   1696 C CZ  . ARG A 1 253 ? 37.73200 22.22600  154.70200 1.000 26.58000 ? 253 ARG A CZ  1 
ATOM   1697 N NH1 . ARG A 1 253 ? 38.92900 22.35200  154.13900 1.000 24.12000 ? 253 ARG A NH1 1 
ATOM   1698 N NH2 . ARG A 1 253 ? 36.90900 23.27200  154.74600 1.000 14.53000 ? 253 ARG A NH2 1 
ATOM   1699 N N   . GLY A 1 254 ? 36.89900 15.60200  153.17100 1.000 7.44000  ? 254 GLY A N   1 
ATOM   1700 C CA  . GLY A 1 254 ? 36.87300 14.82800  151.94800 1.000 7.68000  ? 254 GLY A CA  1 
ATOM   1701 C C   . GLY A 1 254 ? 36.49500 13.38300  152.20500 1.000 6.84000  ? 254 GLY A C   1 
ATOM   1702 O O   . GLY A 1 254 ? 35.73400 12.78800  151.44000 1.000 6.77000  ? 254 GLY A O   1 
ATOM   1703 N N   . PHE A 1 255 ? 37.01900 12.81500  153.29400 1.000 6.35000  ? 255 PHE A N   1 
ATOM   1704 C CA  . PHE A 1 255 ? 36.83400 11.40300  153.62900 1.000 7.61000  ? 255 PHE A CA  1 
ATOM   1705 C C   . PHE A 1 255 ? 36.42200 11.32900  155.09000 1.000 5.87000  ? 255 PHE A C   1 
ATOM   1706 O O   . PHE A 1 255 ? 37.26900 11.22400  155.99400 1.000 6.69000  ? 255 PHE A O   1 
ATOM   1707 C CB  . PHE A 1 255 ? 38.09700 10.60300  153.32700 1.000 7.59000  ? 255 PHE A CB  1 
ATOM   1708 C CG  . PHE A 1 255 ? 38.47000 10.66100  151.88100 1.000 8.20000  ? 255 PHE A CG  1 
ATOM   1709 C CD1 . PHE A 1 255 ? 37.90400 9.78200   150.97900 1.000 11.98000 ? 255 PHE A CD1 1 
ATOM   1710 C CD2 . PHE A 1 255 ? 39.29500 11.67000  151.40800 1.000 11.00000 ? 255 PHE A CD2 1 
ATOM   1711 C CE1 . PHE A 1 255 ? 38.20600 9.86300   149.62200 1.000 13.78000 ? 255 PHE A CE1 1 
ATOM   1712 C CE2 . PHE A 1 255 ? 39.60000 11.76200  150.06000 1.000 11.39000 ? 255 PHE A CE2 1 
ATOM   1713 C CZ  . PHE A 1 255 ? 39.05400 10.86000  149.16800 1.000 16.97000 ? 255 PHE A CZ  1 
ATOM   1714 N N   . PRO A 1 256 ? 35.11700 11.42200  155.36400 1.000 6.79000  ? 256 PRO A N   1 
ATOM   1715 C CA  . PRO A 1 256 ? 34.66400 11.59400  156.74800 1.000 5.81000  ? 256 PRO A CA  1 
ATOM   1716 C C   . PRO A 1 256 ? 34.83300 10.36100  157.62300 1.000 6.05000  ? 256 PRO A C   1 
ATOM   1717 O O   . PRO A 1 256 ? 34.53800 10.44100  158.81700 1.000 5.87000  ? 256 PRO A O   1 
ATOM   1718 C CB  . PRO A 1 256 ? 33.18000 11.98700  156.58400 1.000 6.12000  ? 256 PRO A CB  1 
ATOM   1719 C CG  . PRO A 1 256 ? 32.79600 11.50700  155.21500 1.000 5.71000  ? 256 PRO A CG  1 
ATOM   1720 C CD  . PRO A 1 256 ? 34.03800 11.64200  154.38800 1.000 7.70000  ? 256 PRO A CD  1 
ATOM   1721 N N   . ILE A 1 257 ? 35.33000 9.23500   157.10000 1.000 5.44000  ? 257 ILE A N   1 
ATOM   1722 C CA  . ILE A 1 257 ? 35.75200 8.16800   158.00000 1.000 4.82000  ? 257 ILE A CA  1 
ATOM   1723 C C   . ILE A 1 257 ? 36.83500 8.67700   158.94600 1.000 5.22000  ? 257 ILE A C   1 
ATOM   1724 O O   . ILE A 1 257 ? 37.02300 8.12400   160.03500 1.000 6.00000  ? 257 ILE A O   1 
ATOM   1725 C CB  . ILE A 1 257 ? 36.22900 6.93200   157.19800 1.000 6.51000  ? 257 ILE A CB  1 
ATOM   1726 C CG1 . ILE A 1 257 ? 36.23400 5.68100   158.08700 1.000 6.97000  ? 257 ILE A CG1 1 
ATOM   1727 C CG2 . ILE A 1 257 ? 37.62500 7.16700   156.61200 1.000 7.29000  ? 257 ILE A CG2 1 
ATOM   1728 C CD1 . ILE A 1 257 ? 34.84800 5.15900   158.43000 1.000 7.43000  ? 257 ILE A CD1 1 
ATOM   1729 N N   . LEU A 1 258 ? 37.54500 9.73700   158.55300 1.000 6.62000  ? 258 LEU A N   1 
ATOM   1730 C CA  . LEU A 1 258 ? 38.59200 10.35900  159.35700 1.000 7.01000  ? 258 LEU A CA  1 
ATOM   1731 C C   . LEU A 1 258 ? 38.06300 11.40200  160.32900 1.000 9.08000  ? 258 LEU A C   1 
ATOM   1732 O O   . LEU A 1 258 ? 38.85200 11.95400  161.10700 1.000 8.90000  ? 258 LEU A O   1 
ATOM   1733 C CB  . LEU A 1 258 ? 39.61900 11.02400  158.43900 1.000 5.64000  ? 258 LEU A CB  1 
ATOM   1734 C CG  . LEU A 1 258 ? 40.22300 10.12600  157.36000 1.000 6.43000  ? 258 LEU A CG  1 
ATOM   1735 C CD1 . LEU A 1 258 ? 41.10500 10.96100  156.42900 1.000 9.78000  ? 258 LEU A CD1 1 
ATOM   1736 C CD2 . LEU A 1 258 ? 41.01200 9.00400   157.99100 1.000 11.80000 ? 258 LEU A CD2 1 
ATOM   1737 N N   . GLY A 1 259 ? 36.76600 11.71600  160.27500 1.000 6.33000  ? 259 GLY A N   1 
ATOM   1738 C CA  . GLY A 1 259 ? 36.16900 12.66700  161.18700 1.000 6.81000  ? 259 GLY A CA  1 
ATOM   1739 C C   . GLY A 1 259 ? 35.80200 12.04400  162.52000 1.000 7.18000  ? 259 GLY A C   1 
ATOM   1740 O O   . GLY A 1 259 ? 36.04100 10.86600  162.78500 1.000 7.27000  ? 259 GLY A O   1 
ATOM   1741 N N   . ARG A 1 260 ? 35.20600 12.87100  163.38500 1.000 6.91000  ? 260 ARG A N   1 
ATOM   1742 C CA  . ARG A 1 260 ? 34.82600 12.44500  164.72600 1.000 6.15000  ? 260 ARG A CA  1 
ATOM   1743 C C   . ARG A 1 260 ? 33.52100 11.64800  164.70700 1.000 7.98000  ? 260 ARG A C   1 
ATOM   1744 O O   . ARG A 1 260 ? 32.54400 12.05000  164.06200 1.000 6.74000  ? 260 ARG A O   1 
ATOM   1745 C CB  . ARG A 1 260 ? 34.68200 13.66700  165.63600 1.000 6.21000  ? 260 ARG A CB  1 
ATOM   1746 C CG  . ARG A 1 260 ? 34.31200 13.31500  167.06200 1.000 6.55000  ? 260 ARG A CG  1 
ATOM   1747 C CD  . ARG A 1 260 ? 34.41900 14.52900  167.99800 1.000 10.99000 ? 260 ARG A CD  1 
ATOM   1748 N NE  . ARG A 1 260 ? 34.47600 14.07200  169.38400 1.000 11.89000 ? 260 ARG A NE  1 
ATOM   1749 C CZ  . ARG A 1 260 ? 35.20700 14.64200  170.33700 1.000 22.01000 ? 260 ARG A CZ  1 
ATOM   1750 N NH1 . ARG A 1 260 ? 35.21400 14.12000  171.56000 1.000 21.06000 ? 260 ARG A NH1 1 
ATOM   1751 N NH2 . ARG A 1 260 ? 35.92300 15.73300  170.07500 1.000 15.34000 ? 260 ARG A NH2 1 
ATOM   1752 N N   . HIS A 1 261 ? 33.49600 10.52000  165.42900 1.000 7.04000  ? 261 HIS A N   1 
ATOM   1753 C CA  . HIS A 1 261 ? 32.32100 9.65200   165.43400 1.000 6.66000  ? 261 HIS A CA  1 
ATOM   1754 C C   . HIS A 1 261 ? 31.63500 9.52700   166.78800 1.000 7.30000  ? 261 HIS A C   1 
ATOM   1755 O O   . HIS A 1 261 ? 30.46500 9.12500   166.82900 1.000 6.26000  ? 261 HIS A O   1 
ATOM   1756 C CB  . HIS A 1 261 ? 32.69700 8.24300   164.93800 1.000 7.34000  ? 261 HIS A CB  1 
ATOM   1757 C CG  . HIS A 1 261 ? 33.41000 8.24400   163.62200 1.000 6.96000  ? 261 HIS A CG  1 
ATOM   1758 N ND1 . HIS A 1 261 ? 32.93600 8.92400   162.52000 1.000 6.91000  ? 261 HIS A ND1 1 
ATOM   1759 C CD2 . HIS A 1 261 ? 34.57400 7.66700   163.23600 1.000 7.23000  ? 261 HIS A CD2 1 
ATOM   1760 C CE1 . HIS A 1 261 ? 33.77300 8.76100   161.51000 1.000 7.92000  ? 261 HIS A CE1 1 
ATOM   1761 N NE2 . HIS A 1 261 ? 34.77600 8.00400   161.91900 1.000 8.01000  ? 261 HIS A NE2 1 
ATOM   1762 N N   . ASP A 1 262 ? 32.30200 9.87200   167.88600 1.000 7.30000  ? 262 ASP A N   1 
ATOM   1763 C CA  . ASP A 1 262 ? 31.71000 9.57500   169.18600 1.000 7.18000  ? 262 ASP A CA  1 
ATOM   1764 C C   . ASP A 1 262 ? 30.56000 10.50700  169.55600 1.000 8.88000  ? 262 ASP A C   1 
ATOM   1765 O O   . ASP A 1 262 ? 29.95200 10.31700  170.61400 1.000 7.83000  ? 262 ASP A O   1 
ATOM   1766 C CB  . ASP A 1 262 ? 32.79300 9.57800   170.27700 1.000 9.90000  ? 262 ASP A CB  1 
ATOM   1767 C CG  . ASP A 1 262 ? 33.40800 10.95400  170.51800 1.000 17.93000 ? 262 ASP A CG  1 
ATOM   1768 O OD1 . ASP A 1 262 ? 32.81300 11.97800  170.12100 1.000 13.85000 ? 262 ASP A OD1 1 
ATOM   1769 O OD2 . ASP A 1 262 ? 34.49700 11.00800  171.14000 1.000 20.01000 ? 262 ASP A OD2 1 
ATOM   1770 N N   . ASN A 1 263 ? 30.24000 11.50600  168.72000 1.000 6.19000  ? 263 ASN A N   1 
ATOM   1771 C CA  . ASN A 1 263 ? 29.04300 12.32000  168.91300 1.000 7.00000  ? 263 ASN A CA  1 
ATOM   1772 C C   . ASN A 1 263 ? 28.16900 12.33800  167.66000 1.000 6.22000  ? 263 ASN A C   1 
ATOM   1773 O O   . ASN A 1 263 ? 27.40100 13.28700  167.44100 1.000 6.91000  ? 263 ASN A O   1 
ATOM   1774 C CB  . ASN A 1 263 ? 29.40600 13.74800  169.32400 1.000 9.82000  ? 263 ASN A CB  1 
ATOM   1775 C CG  . ASN A 1 263 ? 30.32200 14.42500  168.32900 1.000 9.50000  ? 263 ASN A CG  1 
ATOM   1776 O OD1 . ASN A 1 263 ? 30.66700 13.84700  167.30500 1.000 9.05000  ? 263 ASN A OD1 1 
ATOM   1777 N ND2 . ASN A 1 263 ? 30.72400 15.66600  168.63000 1.000 9.43000  ? 263 ASN A ND2 1 
ATOM   1778 N N   . ALA A 1 264 ? 28.25600 11.29500  166.83900 1.000 6.59000  ? 264 ALA A N   1 
ATOM   1779 C CA  . ALA A 1 264 ? 27.48800 11.24900  165.60400 1.000 6.31000  ? 264 ALA A CA  1 
ATOM   1780 C C   . ALA A 1 264 ? 25.98800 11.24700  165.89600 1.000 7.13000  ? 264 ALA A C   1 
ATOM   1781 O O   . ALA A 1 264 ? 25.53800 10.66000  166.87900 1.000 7.87000  ? 264 ALA A O   1 
ATOM   1782 C CB  . ALA A 1 264 ? 27.84300 10.00600  164.78800 1.000 6.48000  ? 264 ALA A CB  1 
ATOM   1783 N N   . PRO A 1 265 ? 25.19000 11.86900  165.03700 1.000 7.35000  ? 265 PRO A N   1 
ATOM   1784 C CA  . PRO A 1 265 ? 23.73300 11.82900  165.21400 1.000 7.90000  ? 265 PRO A CA  1 
ATOM   1785 C C   . PRO A 1 265 ? 23.20500 10.42200  164.98000 1.000 9.82000  ? 265 PRO A C   1 
ATOM   1786 O O   . PRO A 1 265 ? 23.94500 9.54900   164.49300 1.000 8.03000  ? 265 PRO A O   1 
ATOM   1787 C CB  . PRO A 1 265 ? 23.21900 12.81200  164.14800 1.000 9.00000  ? 265 PRO A CB  1 
ATOM   1788 C CG  . PRO A 1 265 ? 24.30500 12.86500  163.11200 1.000 9.28000  ? 265 PRO A CG  1 
ATOM   1789 C CD  . PRO A 1 265 ? 25.60300 12.62300  163.83800 1.000 7.31000  ? 265 PRO A CD  1 
ATOM   1790 N N   . PRO A 1 266 ? 21.94800 10.15200  165.34400 1.000 9.71000  ? 266 PRO A N   1 
ATOM   1791 C CA  . PRO A 1 266 ? 21.33300 8.85900   164.99900 1.000 7.80000  ? 266 PRO A CA  1 
ATOM   1792 C C   . PRO A 1 266 ? 21.46500 8.60600   163.50600 1.000 6.47000  ? 266 PRO A C   1 
ATOM   1793 O O   . PRO A 1 266 ? 21.29800 9.52200   162.70300 1.000 5.87000  ? 266 PRO A O   1 
ATOM   1794 C CB  . PRO A 1 266 ? 19.86800 9.04600   165.40500 1.000 6.62000  ? 266 PRO A CB  1 
ATOM   1795 C CG  . PRO A 1 266 ? 19.90700 10.13000  166.46400 1.000 7.62000  ? 266 PRO A CG  1 
ATOM   1796 C CD  . PRO A 1 266 ? 21.00600 11.05300  166.03500 1.000 9.41000  ? 266 PRO A CD  1 
ATOM   1797 N N   . THR A 1 267 ? 21.80100 7.36200   163.13600 1.000 4.81000  ? 267 THR A N   1 
ATOM   1798 C CA  . THR A 1 267 ? 22.25600 7.07900   161.77800 1.000 6.90000  ? 267 THR A CA  1 
ATOM   1799 C C   . THR A 1 267 ? 21.58600 5.84000   161.20000 1.000 5.41000  ? 267 THR A C   1 
ATOM   1800 O O   . THR A 1 267 ? 21.38100 4.84200   161.90100 1.000 6.48000  ? 267 THR A O   1 
ATOM   1801 C CB  . THR A 1 267 ? 23.77800 6.87700   161.73800 1.000 7.28000  ? 267 THR A CB  1 
ATOM   1802 O OG1 . THR A 1 267 ? 24.42400 8.05700   162.21700 1.000 7.81000  ? 267 THR A OG1 1 
ATOM   1803 C CG2 . THR A 1 267 ? 24.25300 6.60200   160.31000 1.000 6.76000  ? 267 THR A CG2 1 
ATOM   1804 N N   . ILE A 1 268 ? 21.23400 5.93000   159.91800 1.000 3.42000  ? 268 ILE A N   1 
ATOM   1805 C CA  . ILE A 1 268 ? 20.89400 4.78600   159.07800 1.000 4.36000  ? 268 ILE A CA  1 
ATOM   1806 C C   . ILE A 1 268 ? 21.89100 4.77500   157.92100 1.000 5.19000  ? 268 ILE A C   1 
ATOM   1807 O O   . ILE A 1 268 ? 21.91200 5.70600   157.11200 1.000 6.75000  ? 268 ILE A O   1 
ATOM   1808 C CB  . ILE A 1 268 ? 19.44700 4.86500   158.55300 1.000 5.07000  ? 268 ILE A CB  1 
ATOM   1809 C CG1 . ILE A 1 268 ? 18.45600 4.92800   159.71900 1.000 6.38000  ? 268 ILE A CG1 1 
ATOM   1810 C CG2 . ILE A 1 268 ? 19.12600 3.68400   157.59400 1.000 5.26000  ? 268 ILE A CG2 1 
ATOM   1811 C CD1 . ILE A 1 268 ? 17.10100 5.50700   159.32000 1.000 5.65000  ? 268 ILE A CD1 1 
ATOM   1812 N N   . VAL A 1 269 ? 22.73500 3.74700   157.85600 1.000 4.10000  ? 269 VAL A N   1 
ATOM   1813 C CA  . VAL A 1 269 ? 23.66500 3.56100   156.73600 1.000 4.45000  ? 269 VAL A CA  1 
ATOM   1814 C C   . VAL A 1 269 ? 23.04800 2.55100   155.78000 1.000 5.23000  ? 269 VAL A C   1 
ATOM   1815 O O   . VAL A 1 269 ? 22.67600 1.44900   156.19900 1.000 6.18000  ? 269 VAL A O   1 
ATOM   1816 C CB  . VAL A 1 269 ? 25.04100 3.07000   157.22300 1.000 5.23000  ? 269 VAL A CB  1 
ATOM   1817 C CG1 . VAL A 1 269 ? 25.93600 2.69500   156.01400 1.000 7.35000  ? 269 VAL A CG1 1 
ATOM   1818 C CG2 . VAL A 1 269 ? 25.71600 4.12600   158.08700 1.000 7.53000  ? 269 VAL A CG2 1 
ATOM   1819 N N   . VAL A 1 270 ? 22.92800 2.91700   154.50000 1.000 4.47000  ? 270 VAL A N   1 
ATOM   1820 C CA  . VAL A 1 270 ? 22.39000 2.02800   153.47700 1.000 5.41000  ? 270 VAL A CA  1 
ATOM   1821 C C   . VAL A 1 270 ? 23.49300 1.74000   152.47100 1.000 6.27000  ? 270 VAL A C   1 
ATOM   1822 O O   . VAL A 1 270 ? 24.11000 2.67000   151.94300 1.000 6.55000  ? 270 VAL A O   1 
ATOM   1823 C CB  . VAL A 1 270 ? 21.16600 2.63500   152.76500 1.000 5.67000  ? 270 VAL A CB  1 
ATOM   1824 C CG1 . VAL A 1 270 ? 20.56400 1.61200   151.78100 1.000 6.96000  ? 270 VAL A CG1 1 
ATOM   1825 C CG2 . VAL A 1 270 ? 20.12900 3.08900   153.79200 1.000 7.29000  ? 270 VAL A CG2 1 
ATOM   1826 N N   . THR A 1 271 ? 23.74500 0.46000   152.21100 1.000 4.37000  ? 271 THR A N   1 
ATOM   1827 C CA  . THR A 1 271 ? 24.67300 0.06300   151.16200 1.000 5.11000  ? 271 THR A CA  1 
ATOM   1828 C C   . THR A 1 271 ? 23.95400 -0.83000  150.15700 1.000 5.71000  ? 271 THR A C   1 
ATOM   1829 O O   . THR A 1 271 ? 22.81000 -1.25600  150.36500 1.000 6.01000  ? 271 THR A O   1 
ATOM   1830 C CB  . THR A 1 271 ? 25.89100 -0.67300  151.73800 1.000 5.31000  ? 271 THR A CB  1 
ATOM   1831 O OG1 . THR A 1 271 ? 25.43800 -1.82200  152.46500 1.000 6.27000  ? 271 THR A OG1 1 
ATOM   1832 C CG2 . THR A 1 271 ? 26.68500 0.23300   152.67700 1.000 5.95000  ? 271 THR A CG2 1 
ATOM   1833 N N   . ALA A 1 272 ? 24.63300 -1.10000  149.04300 1.000 5.15000  ? 272 ALA A N   1 
ATOM   1834 C CA  . ALA A 1 272 ? 24.15500 -2.03900  148.03500 1.000 7.01000  ? 272 ALA A CA  1 
ATOM   1835 C C   . ALA A 1 272 ? 25.17200 -3.16500  147.87400 1.000 6.12000  ? 272 ALA A C   1 
ATOM   1836 O O   . ALA A 1 272 ? 26.37900 -2.91700  147.85000 1.000 6.40000  ? 272 ALA A O   1 
ATOM   1837 C CB  . ALA A 1 272 ? 23.93100 -1.33800  146.68600 1.000 5.75000  ? 272 ALA A CB  1 
ATOM   1838 N N   . SER A 1 273 ? 24.69000 -4.40500  147.74700 1.000 6.25000  ? 273 SER A N   1 
ATOM   1839 C CA  . SER A 1 273 ? 25.61600 -5.53900  147.79400 1.000 6.98000  ? 273 SER A CA  1 
ATOM   1840 C C   . SER A 1 273 ? 26.51800 -5.62600  146.56600 1.000 6.90000  ? 273 SER A C   1 
ATOM   1841 O O   . SER A 1 273 ? 27.60200 -6.21800  146.65700 1.000 8.27000  ? 273 SER A O   1 
ATOM   1842 C CB  . SER A 1 273 ? 24.86000 -6.85900  147.96300 1.000 6.99000  ? 273 SER A CB  1 
ATOM   1843 O OG  . SER A 1 273 ? 24.17100 -7.21800  146.77600 1.000 7.16000  ? 273 SER A OG  1 
ATOM   1844 N N   . LEU A 1 274 ? 26.10300 -5.06400  145.42800 1.000 5.16000  ? 274 LEU A N   1 
ATOM   1845 C CA  . LEU A 1 274 ? 26.85900 -5.13000  144.18200 1.000 5.70000  ? 274 LEU A CA  1 
ATOM   1846 C C   . LEU A 1 274 ? 27.54000 -3.80100  143.86700 1.000 8.81000  ? 274 LEU A C   1 
ATOM   1847 O O   . LEU A 1 274 ? 27.67400 -3.43000  142.70600 1.000 12.10000 ? 274 LEU A O   1 
ATOM   1848 C CB  . LEU A 1 274 ? 25.94700 -5.53400  143.02000 1.000 5.63000  ? 274 LEU A CB  1 
ATOM   1849 C CG  . LEU A 1 274 ? 25.19400 -6.85100  143.20700 1.000 7.93000  ? 274 LEU A CG  1 
ATOM   1850 C CD1 . LEU A 1 274 ? 24.15200 -7.03700  142.12500 1.000 10.58000 ? 274 LEU A CD1 1 
ATOM   1851 C CD2 . LEU A 1 274 ? 26.20800 -8.00100  143.19800 1.000 10.49000 ? 274 LEU A CD2 1 
ATOM   1852 N N   . ASP A 1 275 ? 27.96000 -3.07500  144.89000 1.000 10.30000 ? 275 ASP A N   1 
ATOM   1853 C CA  . ASP A 1 275 ? 28.46600 -1.72000  144.72800 1.000 7.67000  ? 275 ASP A CA  1 
ATOM   1854 C C   . ASP A 1 275 ? 29.97000 -1.70000  144.93700 1.000 6.92000  ? 275 ASP A C   1 
ATOM   1855 O O   . ASP A 1 275 ? 30.43900 -2.16100  145.98500 1.000 7.81000  ? 275 ASP A O   1 
ATOM   1856 C CB  . ASP A 1 275 ? 27.77800 -0.81100  145.75200 1.000 7.84000  ? 275 ASP A CB  1 
ATOM   1857 C CG  . ASP A 1 275 ? 28.09100 0.65400   145.56500 1.000 9.17000  ? 275 ASP A CG  1 
ATOM   1858 O OD1 . ASP A 1 275 ? 29.07600 1.01100   144.87600 1.000 8.46000  ? 275 ASP A OD1 1 
ATOM   1859 O OD2 . ASP A 1 275 ? 27.34000 1.47200   146.14200 1.000 12.60000 ? 275 ASP A OD2 1 
ATOM   1860 N N   . PRO A 1 276 ? 30.75400 -1.16900  143.99300 1.000 7.59000  ? 276 PRO A N   1 
ATOM   1861 C CA  . PRO A 1 276 ? 32.20700 -1.07900  144.21900 1.000 8.53000  ? 276 PRO A CA  1 
ATOM   1862 C C   . PRO A 1 276 ? 32.59600 -0.26100  145.43800 1.000 8.54000  ? 276 PRO A C   1 
ATOM   1863 O O   . PRO A 1 276 ? 33.67800 -0.49300  145.99000 1.000 8.43000  ? 276 PRO A O   1 
ATOM   1864 C CB  . PRO A 1 276 ? 32.72600 -0.42600  142.92900 1.000 9.75000  ? 276 PRO A CB  1 
ATOM   1865 C CG  . PRO A 1 276 ? 31.50800 0.22500   142.31100 1.000 9.29000  ? 276 PRO A CG  1 
ATOM   1866 C CD  . PRO A 1 276 ? 30.37800 -0.68900  142.65500 1.000 9.72000  ? 276 PRO A CD  1 
ATOM   1867 N N   . ILE A 1 277 ? 31.77400 0.69400   145.87400 1.000 7.94000  ? 277 ILE A N   1 
ATOM   1868 C CA  . ILE A 1 277 ? 32.07000 1.43500   147.09900 1.000 5.60000  ? 277 ILE A CA  1 
ATOM   1869 C C   . ILE A 1 277 ? 31.24000 0.93200   148.28300 1.000 6.72000  ? 277 ILE A C   1 
ATOM   1870 O O   . ILE A 1 277 ? 31.12300 1.62100   149.29800 1.000 5.98000  ? 277 ILE A O   1 
ATOM   1871 C CB  . ILE A 1 277 ? 31.92700 2.95300   146.90900 1.000 9.44000  ? 277 ILE A CB  1 
ATOM   1872 C CG1 . ILE A 1 277 ? 30.46400 3.38300   146.73900 1.000 7.64000  ? 277 ILE A CG1 1 
ATOM   1873 C CG2 . ILE A 1 277 ? 32.77700 3.41900   145.73100 1.000 8.85000  ? 277 ILE A CG2 1 
ATOM   1874 C CD1 . ILE A 1 277 ? 30.28200 4.88900   146.98600 1.000 8.44000  ? 277 ILE A CD1 1 
ATOM   1875 N N   . ARG A 1 278 ? 30.69600 -0.28000  148.18200 1.000 6.13000  ? 278 ARG A N   1 
ATOM   1876 C CA  . ARG A 1 278 ? 29.97300 -0.88900  149.29900 1.000 7.33000  ? 278 ARG A CA  1 
ATOM   1877 C C   . ARG A 1 278 ? 30.79900 -0.89000  150.58200 1.000 7.79000  ? 278 ARG A C   1 
ATOM   1878 O O   . ARG A 1 278 ? 30.27900 -0.61200  151.67200 1.000 5.82000  ? 278 ARG A O   1 
ATOM   1879 C CB  . ARG A 1 278 ? 29.57900 -2.31300  148.91000 1.000 7.17000  ? 278 ARG A CB  1 
ATOM   1880 C CG  . ARG A 1 278 ? 28.94700 -3.14800  149.99000 1.000 9.73000  ? 278 ARG A CG  1 
ATOM   1881 C CD  . ARG A 1 278 ? 28.99000 -4.61600  149.55300 1.000 9.10000  ? 278 ARG A CD  1 
ATOM   1882 N NE  . ARG A 1 278 ? 30.31500 -5.20100  149.75100 1.000 13.03000 ? 278 ARG A NE  1 
ATOM   1883 C CZ  . ARG A 1 278 ? 30.67400 -6.40200  149.31200 1.000 10.02000 ? 278 ARG A CZ  1 
ATOM   1884 N NH1 . ARG A 1 278 ? 31.89600 -6.85300  149.55700 1.000 15.76000 ? 278 ARG A NH1 1 
ATOM   1885 N NH2 . ARG A 1 278 ? 29.80800 -7.15400  148.64000 1.000 10.32000 ? 278 ARG A NH2 1 
ATOM   1886 N N   . ASP A 1 279 ? 32.09300 -1.19900  150.48000 1.000 5.72000  ? 279 ASP A N   1 
ATOM   1887 C CA  . ASP A 1 279 ? 32.87300 -1.34300  151.70000 1.000 7.39000  ? 279 ASP A CA  1 
ATOM   1888 C C   . ASP A 1 279 ? 33.12100 -0.00200  152.37300 1.000 7.75000  ? 279 ASP A C   1 
ATOM   1889 O O   . ASP A 1 279 ? 33.42900 0.02600   153.56900 1.000 6.86000  ? 279 ASP A O   1 
ATOM   1890 C CB  . ASP A 1 279 ? 34.19900 -2.05100  151.40700 1.000 8.92000  ? 279 ASP A CB  1 
ATOM   1891 C CG  . ASP A 1 279 ? 34.01300 -3.51200  151.02500 1.000 12.19000 ? 279 ASP A CG  1 
ATOM   1892 O OD1 . ASP A 1 279 ? 32.87100 -4.03400  151.07900 1.000 9.32000  ? 279 ASP A OD1 1 
ATOM   1893 O OD2 . ASP A 1 279 ? 35.02200 -4.14300  150.65500 1.000 13.49000 ? 279 ASP A OD2 1 
ATOM   1894 N N   . SER A 1 280 ? 32.95800 1.10000   151.63500 1.000 6.18000  ? 280 SER A N   1 
ATOM   1895 C CA  . SER A 1 280 ? 33.09700 2.43200   152.22100 1.000 8.04000  ? 280 SER A CA  1 
ATOM   1896 C C   . SER A 1 280 ? 31.95400 2.71800   153.19400 1.000 9.68000  ? 280 SER A C   1 
ATOM   1897 O O   . SER A 1 280 ? 32.17800 3.23600   154.29600 1.000 7.91000  ? 280 SER A O   1 
ATOM   1898 C CB  . SER A 1 280 ? 33.14200 3.47200   151.09800 1.000 10.68000 ? 280 SER A CB  1 
ATOM   1899 O OG  . SER A 1 280 ? 33.44000 4.77400   151.57400 1.000 10.86000 ? 280 SER A OG  1 
ATOM   1900 N N   . GLY A 1 281 ? 30.72300 2.37400   152.81100 1.000 6.13000  ? 281 GLY A N   1 
ATOM   1901 C CA  . GLY A 1 281 ? 29.60000 2.53600   153.72500 1.000 5.58000  ? 281 GLY A CA  1 
ATOM   1902 C C   . GLY A 1 281 ? 29.65000 1.55400   154.88200 1.000 5.52000  ? 281 GLY A C   1 
ATOM   1903 O O   . GLY A 1 281 ? 29.31900 1.90300   156.01500 1.000 5.68000  ? 281 GLY A O   1 
ATOM   1904 N N   . ARG A 1 282 ? 30.04600 0.30900   154.60700 1.000 4.65000  ? 282 ARG A N   1 
ATOM   1905 C CA  . ARG A 1 282 ? 30.25900 -0.66200  155.67900 1.000 6.03000  ? 282 ARG A CA  1 
ATOM   1906 C C   . ARG A 1 282 ? 31.25900 -0.14700  156.70800 1.000 5.34000  ? 282 ARG A C   1 
ATOM   1907 O O   . ARG A 1 282 ? 31.05900 -0.31500  157.91500 1.000 5.02000  ? 282 ARG A O   1 
ATOM   1908 C CB  . ARG A 1 282 ? 30.75400 -1.98500  155.10100 1.000 4.96000  ? 282 ARG A CB  1 
ATOM   1909 C CG  . ARG A 1 282 ? 29.74100 -2.77300  154.28500 1.000 5.86000  ? 282 ARG A CG  1 
ATOM   1910 C CD  . ARG A 1 282 ? 30.39200 -4.09700  153.87500 1.000 7.14000  ? 282 ARG A CD  1 
ATOM   1911 N NE  . ARG A 1 282 ? 29.49200 -4.99200  153.15000 1.000 7.60000  ? 282 ARG A NE  1 
ATOM   1912 C CZ  . ARG A 1 282 ? 29.85100 -6.21100  152.76100 1.000 8.53000  ? 282 ARG A CZ  1 
ATOM   1913 N NH1 . ARG A 1 282 ? 29.00600 -6.99200  152.09900 1.000 8.29000  ? 282 ARG A NH1 1 
ATOM   1914 N NH2 . ARG A 1 282 ? 31.07400 -6.64500  153.03900 1.000 8.21000  ? 282 ARG A NH2 1 
ATOM   1915 N N   . ALA A 1 283 ? 32.35400 0.45800   156.24600 1.000 4.48000  ? 283 ALA A N   1 
ATOM   1916 C CA  . ALA A 1 283 ? 33.36100 0.97700   157.16900 1.000 5.61000  ? 283 ALA A CA  1 
ATOM   1917 C C   . ALA A 1 283 ? 32.76800 2.03500   158.08900 1.000 4.00000  ? 283 ALA A C   1 
ATOM   1918 O O   . ALA A 1 283 ? 33.11700 2.10600   159.27100 1.000 5.46000  ? 283 ALA A O   1 
ATOM   1919 C CB  . ALA A 1 283 ? 34.53900 1.56200   156.38700 1.000 5.97000  ? 283 ALA A CB  1 
ATOM   1920 N N   . TYR A 1 284 ? 31.87500 2.87800   157.56200 1.000 4.42000  ? 284 TYR A N   1 
ATOM   1921 C CA  . TYR A 1 284 ? 31.30200 3.92400   158.39900 1.000 6.32000  ? 284 TYR A CA  1 
ATOM   1922 C C   . TYR A 1 284 ? 30.40000 3.34000   159.48100 1.000 5.15000  ? 284 TYR A C   1 
ATOM   1923 O O   . TYR A 1 284 ? 30.46700 3.76200   160.64100 1.000 5.04000  ? 284 TYR A O   1 
ATOM   1924 C CB  . TYR A 1 284 ? 30.53700 4.93800   157.54800 1.000 4.25000  ? 284 TYR A CB  1 
ATOM   1925 C CG  . TYR A 1 284 ? 30.04400 6.11100   158.36900 1.000 4.33000  ? 284 TYR A CG  1 
ATOM   1926 C CD1 . TYR A 1 284 ? 30.91800 6.82000   159.19200 1.000 4.73000  ? 284 TYR A CD1 1 
ATOM   1927 C CD2 . TYR A 1 284 ? 28.70200 6.50200   158.33700 1.000 4.87000  ? 284 TYR A CD2 1 
ATOM   1928 C CE1 . TYR A 1 284 ? 30.46600 7.89800   159.96300 1.000 6.45000  ? 284 TYR A CE1 1 
ATOM   1929 C CE2 . TYR A 1 284 ? 28.24600 7.58000   159.08900 1.000 5.41000  ? 284 TYR A CE2 1 
ATOM   1930 C CZ  . TYR A 1 284 ? 29.12700 8.27100   159.89800 1.000 5.79000  ? 284 TYR A CZ  1 
ATOM   1931 O OH  . TYR A 1 284 ? 28.68700 9.32900   160.67200 1.000 6.00000  ? 284 TYR A OH  1 
ATOM   1932 N N   . ALA A 1 285 ? 29.53100 2.39000   159.12200 1.000 4.54000  ? 285 ALA A N   1 
ATOM   1933 C CA  . ALA A 1 285 ? 28.70700 1.73800   160.14000 1.000 5.45000  ? 285 ALA A CA  1 
ATOM   1934 C C   . ALA A 1 285 ? 29.57800 1.11500   161.22700 1.000 5.67000  ? 285 ALA A C   1 
ATOM   1935 O O   . ALA A 1 285 ? 29.25700 1.19100   162.41900 1.000 5.63000  ? 285 ALA A O   1 
ATOM   1936 C CB  . ALA A 1 285 ? 27.80900 0.67900   159.49600 1.000 6.22000  ? 285 ALA A CB  1 
ATOM   1937 N N   . LYS A 1 286 ? 30.69000 0.50400   160.83500 1.000 5.11000  ? 286 LYS A N   1 
ATOM   1938 C CA  . LYS A 1 286 ? 31.56800 -0.09800  161.83500 1.000 5.36000  ? 286 LYS A CA  1 
ATOM   1939 C C   . LYS A 1 286 ? 32.23200 0.95500   162.70700 1.000 5.02000  ? 286 LYS A C   1 
ATOM   1940 O O   . LYS A 1 286 ? 32.43400 0.72200   163.89900 1.000 6.01000  ? 286 LYS A O   1 
ATOM   1941 C CB  . LYS A 1 286 ? 32.62400 -0.96200  161.14900 1.000 6.04000  ? 286 LYS A CB  1 
ATOM   1942 C CG  . LYS A 1 286 ? 32.06700 -2.27100  160.60000 1.000 6.69000  ? 286 LYS A CG  1 
ATOM   1943 C CD  . LYS A 1 286 ? 33.04000 -2.94300  159.62000 1.000 13.89000 ? 286 LYS A CD  1 
ATOM   1944 C CE  . LYS A 1 286 ? 34.32400 -3.38500  160.29000 1.000 15.45000 ? 286 LYS A CE  1 
ATOM   1945 N NZ  . LYS A 1 286 ? 35.31800 -3.89900  159.27000 1.000 13.17000 ? 286 LYS A NZ  1 
ATOM   1946 N N   . ALA A 1 287 ? 32.57900 2.10700   162.13400 1.000 4.53000  ? 287 ALA A N   1 
ATOM   1947 C CA  . ALA A 1 287 ? 33.18500 3.17600   162.92300 1.000 6.28000  ? 287 ALA A CA  1 
ATOM   1948 C C   . ALA A 1 287 ? 32.20700 3.72000   163.95100 1.000 7.11000  ? 287 ALA A C   1 
ATOM   1949 O O   . ALA A 1 287 ? 32.60400 4.08300   165.06600 1.000 5.93000  ? 287 ALA A O   1 
ATOM   1950 C CB  . ALA A 1 287 ? 33.66900 4.29600   162.00000 1.000 7.32000  ? 287 ALA A CB  1 
ATOM   1951 N N   . LEU A 1 288 ? 30.92700 3.80400   163.58800 1.000 6.34000  ? 288 LEU A N   1 
ATOM   1952 C CA  . LEU A 1 288 ? 29.93000 4.25700   164.55300 1.000 6.15000  ? 288 LEU A CA  1 
ATOM   1953 C C   . LEU A 1 288 ? 29.78800 3.26500   165.70000 1.000 5.65000  ? 288 LEU A C   1 
ATOM   1954 O O   . LEU A 1 288 ? 29.71500 3.66500   166.86900 1.000 7.43000  ? 288 LEU A O   1 
ATOM   1955 C CB  . LEU A 1 288 ? 28.58900 4.47200   163.85400 1.000 7.31000  ? 288 LEU A CB  1 
ATOM   1956 C CG  . LEU A 1 288 ? 28.58900 5.60900   162.83400 1.000 8.23000  ? 288 LEU A CG  1 
ATOM   1957 C CD1 . LEU A 1 288 ? 27.24900 5.66600   162.11600 1.000 10.26000 ? 288 LEU A CD1 1 
ATOM   1958 C CD2 . LEU A 1 288 ? 28.91300 6.93800   163.52000 1.000 9.76000  ? 288 LEU A CD2 1 
ATOM   1959 N N   . ILE A 1 289 ? 29.76400 1.96900   165.38500 1.000 5.63000  ? 289 ILE A N   1 
ATOM   1960 C CA  . ILE A 1 289 ? 29.70500 0.94300   166.42300 1.000 6.49000  ? 289 ILE A CA  1 
ATOM   1961 C C   . ILE A 1 289 ? 30.92100 1.03800   167.33700 1.000 5.20000  ? 289 ILE A C   1 
ATOM   1962 O O   . ILE A 1 289 ? 30.79900 0.95800   168.56200 1.000 6.22000  ? 289 ILE A O   1 
ATOM   1963 C CB  . ILE A 1 289 ? 29.59600 -0.45000  165.77700 1.000 6.22000  ? 289 ILE A CB  1 
ATOM   1964 C CG1 . ILE A 1 289 ? 28.24000 -0.60300  165.09000 1.000 7.05000  ? 289 ILE A CG1 1 
ATOM   1965 C CG2 . ILE A 1 289 ? 29.82900 -1.55600  166.82500 1.000 8.49000  ? 289 ILE A CG2 1 
ATOM   1966 C CD1 . ILE A 1 289 ? 28.20800 -1.75900  164.15700 1.000 9.01000  ? 289 ILE A CD1 1 
ATOM   1967 N N   . ASP A 1 290 ? 32.10900 1.21600   166.74900 1.000 6.89000  ? 290 ASP A N   1 
ATOM   1968 C CA  . ASP A 1 290 ? 33.33000 1.40200   167.53400 1.000 7.18000  ? 290 ASP A CA  1 
ATOM   1969 C C   . ASP A 1 290 ? 33.24200 2.60800   168.46200 1.000 8.32000  ? 290 ASP A C   1 
ATOM   1970 O O   . ASP A 1 290 ? 33.95100 2.66500   169.47700 1.000 9.56000  ? 290 ASP A O   1 
ATOM   1971 C CB  . ASP A 1 290 ? 34.53700 1.58300   166.60400 1.000 7.94000  ? 290 ASP A CB  1 
ATOM   1972 C CG  . ASP A 1 290 ? 35.07200 0.26900   166.05400 1.000 14.37000 ? 290 ASP A CG  1 
ATOM   1973 O OD1 . ASP A 1 290 ? 34.74400 -0.80800  166.60200 1.000 16.16000 ? 290 ASP A OD1 1 
ATOM   1974 O OD2 . ASP A 1 290 ? 35.84600 0.32100   165.07300 1.000 17.28000 ? 290 ASP A OD2 1 
ATOM   1975 N N   . ALA A 1 291 ? 32.42300 3.59500   168.11500 1.000 6.83000  ? 291 ALA A N   1 
ATOM   1976 C CA  . ALA A 1 291 ? 32.23300 4.78600   168.93500 1.000 7.41000  ? 291 ALA A CA  1 
ATOM   1977 C C   . ALA A 1 291 ? 30.99900 4.70100   169.83200 1.000 8.97000  ? 291 ALA A C   1 
ATOM   1978 O O   . ALA A 1 291 ? 30.65900 5.68700   170.49800 1.000 9.32000  ? 291 ALA A O   1 
ATOM   1979 C CB  . ALA A 1 291 ? 32.15500 6.02900   168.04500 1.000 8.10000  ? 291 ALA A CB  1 
ATOM   1980 N N   . GLY A 1 292 ? 30.32800 3.55400   169.87100 1.000 8.33000  ? 292 GLY A N   1 
ATOM   1981 C CA  . GLY A 1 292 ? 29.16900 3.38400   170.73200 1.000 6.62000  ? 292 GLY A CA  1 
ATOM   1982 C C   . GLY A 1 292 ? 27.93100 4.13700   170.28000 1.000 7.23000  ? 292 GLY A C   1 
ATOM   1983 O O   . GLY A 1 292 ? 27.10200 4.51400   171.12100 1.000 7.92000  ? 292 GLY A O   1 
ATOM   1984 N N   . ARG A 1 293 ? 27.78500 4.37500   168.97800 1.000 5.73000  ? 293 ARG A N   1 
ATOM   1985 C CA  . ARG A 1 293 ? 26.70300 5.19800   168.44000 1.000 7.94000  ? 293 ARG A CA  1 
ATOM   1986 C C   . ARG A 1 293 ? 25.68700 4.33600   167.70000 1.000 7.77000  ? 293 ARG A C   1 
ATOM   1987 O O   . ARG A 1 293 ? 26.06200 3.55600   166.81600 1.000 9.22000  ? 293 ARG A O   1 
ATOM   1988 C CB  . ARG A 1 293 ? 27.25200 6.27500   167.49200 1.000 7.93000  ? 293 ARG A CB  1 
ATOM   1989 C CG  . ARG A 1 293 ? 28.30800 7.17200   168.12500 1.000 10.85000 ? 293 ARG A CG  1 
ATOM   1990 C CD  . ARG A 1 293 ? 27.80500 7.84100   169.38200 1.000 10.30000 ? 293 ARG A CD  1 
ATOM   1991 N NE  . ARG A 1 293 ? 26.82900 8.88900   169.08900 1.000 9.37000  ? 293 ARG A NE  1 
ATOM   1992 C CZ  . ARG A 1 293 ? 26.33500 9.73300   169.98700 1.000 10.63000 ? 293 ARG A CZ  1 
ATOM   1993 N NH1 . ARG A 1 293 ? 26.71100 9.66200   171.26100 1.000 14.17000 ? 293 ARG A NH1 1 
ATOM   1994 N NH2 . ARG A 1 293 ? 25.44600 10.64700  169.61100 1.000 11.26000 ? 293 ARG A NH2 1 
ATOM   1995 N N   . ASP A 1 294 ? 24.40100 4.51400   168.03300 1.000 7.37000  ? 294 ASP A N   1 
ATOM   1996 C CA  . ASP A 1 294 ? 23.32200 3.77700   167.37000 1.000 7.62000  ? 294 ASP A CA  1 
ATOM   1997 C C   . ASP A 1 294 ? 23.44000 3.87400   165.86000 1.000 9.02000  ? 294 ASP A C   1 
ATOM   1998 O O   . ASP A 1 294 ? 23.66200 4.95400   165.30700 1.000 8.79000  ? 294 ASP A O   1 
ATOM   1999 C CB  . ASP A 1 294 ? 21.95200 4.33600   167.76600 1.000 6.53000  ? 294 ASP A CB  1 
ATOM   2000 C CG  . ASP A 1 294 ? 21.65700 4.19900   169.23800 1.000 10.23000 ? 294 ASP A CG  1 
ATOM   2001 O OD1 . ASP A 1 294 ? 22.27200 3.32600   169.87700 1.000 10.27000 ? 294 ASP A OD1 1 
ATOM   2002 O OD2 . ASP A 1 294 ? 20.79500 4.96400   169.74000 1.000 11.84000 ? 294 ASP A OD2 1 
ATOM   2003 N N   . CYS A 1 295 ? 23.22700 2.74800   165.19000 1.000 6.62000  ? 295 CYS A N   1 
ATOM   2004 C CA  . CYS A 1 295 ? 23.26100 2.74000   163.73200 1.000 6.22000  ? 295 CYS A CA  1 
ATOM   2005 C C   . CYS A 1 295 ? 22.40200 1.61100   163.18700 1.000 7.61000  ? 295 CYS A C   1 
ATOM   2006 O O   . CYS A 1 295 ? 22.60900 0.44700   163.54400 1.000 9.27000  ? 295 CYS A O   1 
ATOM   2007 C CB  . CYS A 1 295 ? 24.70600 2.57200   163.24600 1.000 8.09000  ? 295 CYS A CB  1 
ATOM   2008 S SG  . CYS A 1 295 ? 24.89100 2.67300   161.45200 1.000 14.07000 ? 295 CYS A SG  1 
ATOM   2009 N N   . VAL A 1 296 ? 21.47600 1.94800   162.30100 1.000 6.89000  ? 296 VAL A N   1 
ATOM   2010 C CA  . VAL A 1 296 ? 20.75800 0.95200   161.51900 1.000 4.84000  ? 296 VAL A CA  1 
ATOM   2011 C C   . VAL A 1 296 ? 21.56500 0.71000   160.25300 1.000 8.20000  ? 296 VAL A C   1 
ATOM   2012 O O   . VAL A 1 296 ? 21.74700 1.63600   159.46100 1.000 8.39000  ? 296 VAL A O   1 
ATOM   2013 C CB  . VAL A 1 296 ? 19.35500 1.45200   161.17200 1.000 6.93000  ? 296 VAL A CB  1 
ATOM   2014 C CG1 . VAL A 1 296 ? 18.65100 0.44200   160.29300 1.000 10.12000 ? 296 VAL A CG1 1 
ATOM   2015 C CG2 . VAL A 1 296 ? 18.56300 1.75300   162.44100 1.000 8.23000  ? 296 VAL A CG2 1 
ATOM   2016 N N   . PHE A 1 297 ? 22.05600 -0.51200  160.06400 1.000 5.85000  ? 297 PHE A N   1 
ATOM   2017 C CA  . PHE A 1 297 ? 22.79500 -0.87600  158.85800 1.000 7.48000  ? 297 PHE A CA  1 
ATOM   2018 C C   . PHE A 1 297 ? 21.89500 -1.71800  157.96200 1.000 6.88000  ? 297 PHE A C   1 
ATOM   2019 O O   . PHE A 1 297 ? 21.50200 -2.82200  158.34300 1.000 5.54000  ? 297 PHE A O   1 
ATOM   2020 C CB  . PHE A 1 297 ? 24.07000 -1.65000  159.19700 1.000 5.29000  ? 297 PHE A CB  1 
ATOM   2021 C CG  . PHE A 1 297 ? 24.78900 -2.18900  157.98100 1.000 4.75000  ? 297 PHE A CG  1 
ATOM   2022 C CD1 . PHE A 1 297 ? 25.49700 -1.34100  157.14900 1.000 6.30000  ? 297 PHE A CD1 1 
ATOM   2023 C CD2 . PHE A 1 297 ? 24.74400 -3.53800  157.66800 1.000 7.34000  ? 297 PHE A CD2 1 
ATOM   2024 C CE1 . PHE A 1 297 ? 26.15800 -1.81800  156.03000 1.000 7.09000  ? 297 PHE A CE1 1 
ATOM   2025 C CE2 . PHE A 1 297 ? 25.40400 -4.02500  156.54400 1.000 7.02000  ? 297 PHE A CE2 1 
ATOM   2026 C CZ  . PHE A 1 297 ? 26.10300 -3.16200  155.72200 1.000 5.98000  ? 297 PHE A CZ  1 
ATOM   2027 N N   . LEU A 1 298 ? 21.58800 -1.20600  156.76700 1.000 5.39000  ? 298 LEU A N   1 
ATOM   2028 C CA  . LEU A 1 298 ? 20.81300 -1.93700  155.76900 1.000 5.45000  ? 298 LEU A CA  1 
ATOM   2029 C C   . LEU A 1 298 ? 21.66800 -2.10600  154.52300 1.000 6.42000  ? 298 LEU A C   1 
ATOM   2030 O O   . LEU A 1 298 ? 22.00300 -1.11800  153.86800 1.000 8.50000  ? 298 LEU A O   1 
ATOM   2031 C CB  . LEU A 1 298 ? 19.52300 -1.19100  155.41100 1.000 5.98000  ? 298 LEU A CB  1 
ATOM   2032 C CG  . LEU A 1 298 ? 18.56700 -0.91000  156.56800 1.000 7.63000  ? 298 LEU A CG  1 
ATOM   2033 C CD1 . LEU A 1 298 ? 17.40500 -0.04800  156.08200 1.000 7.62000  ? 298 LEU A CD1 1 
ATOM   2034 C CD2 . LEU A 1 298 ? 18.06000 -2.21800  157.16800 1.000 10.41000 ? 298 LEU A CD2 1 
ATOM   2035 N N   . GLU A 1 299 ? 21.99300 -3.34700  154.17800 1.000 5.48000  ? 299 GLU A N   1 
ATOM   2036 C CA  . GLU A 1 299 ? 22.61800 -3.64500  152.89500 1.000 6.12000  ? 299 GLU A CA  1 
ATOM   2037 C C   . GLU A 1 299 ? 21.58700 -4.31300  151.99900 1.000 7.36000  ? 299 GLU A C   1 
ATOM   2038 O O   . GLU A 1 299 ? 21.11100 -5.42000  152.30200 1.000 6.32000  ? 299 GLU A O   1 
ATOM   2039 C CB  . GLU A 1 299 ? 23.85000 -4.53100  153.04400 1.000 6.19000  ? 299 GLU A CB  1 
ATOM   2040 C CG  . GLU A 1 299 ? 24.50200 -4.79800  151.68000 1.000 7.04000  ? 299 GLU A CG  1 
ATOM   2041 C CD  . GLU A 1 299 ? 25.98400 -5.10500  151.78100 1.000 8.47000  ? 299 GLU A CD  1 
ATOM   2042 O OE1 . GLU A 1 299 ? 26.73700 -4.27300  152.35400 1.000 8.02000  ? 299 GLU A OE1 1 
ATOM   2043 O OE2 . GLU A 1 299 ? 26.39000 -6.18700  151.28600 1.000 8.37000  ? 299 GLU A OE2 1 
ATOM   2044 N N   . MET A 1 300 ? 21.23200 -3.63200  150.91500 1.000 6.11000  ? 300 MET A N   1 
ATOM   2045 C CA  . MET A 1 300 ? 20.24400 -4.15400  149.98000 1.000 6.62000  ? 300 MET A CA  1 
ATOM   2046 C C   . MET A 1 300 ? 20.90400 -5.22200  149.11100 1.000 5.95000  ? 300 MET A C   1 
ATOM   2047 O O   . MET A 1 300 ? 21.90300 -4.95300  148.43200 1.000 6.93000  ? 300 MET A O   1 
ATOM   2048 C CB  . MET A 1 300 ? 19.67200 -3.01900  149.14000 1.000 7.50000  ? 300 MET A CB  1 
ATOM   2049 C CG  . MET A 1 300 ? 19.08200 -1.88400  149.96600 1.000 7.17000  ? 300 MET A CG  1 
ATOM   2050 S SD  . MET A 1 300 ? 17.86900 -2.49800  151.17700 1.000 9.68000  ? 300 MET A SD  1 
ATOM   2051 C CE  . MET A 1 300 ? 17.35400 -0.95400  151.96700 1.000 7.74000  ? 300 MET A CE  1 
ATOM   2052 N N   . ARG A 1 301 ? 20.36100 -6.42400  149.20800 1.000 5.75000  ? 301 ARG A N   1 
ATOM   2053 C CA  . ARG A 1 301 ? 20.99300 -7.57900  148.53800 1.000 5.23000  ? 301 ARG A CA  1 
ATOM   2054 C C   . ARG A 1 301 ? 20.53400 -7.77200  147.09000 1.000 6.77000  ? 301 ARG A C   1 
ATOM   2055 O O   . ARG A 1 301 ? 19.34000 -7.85200  146.85300 1.000 6.05000  ? 301 ARG A O   1 
ATOM   2056 C CB  . ARG A 1 301 ? 20.70300 -8.86400  149.32500 1.000 6.83000  ? 301 ARG A CB  1 
ATOM   2057 C CG  . ARG A 1 301 ? 21.34400 -8.89300  150.70200 1.000 12.96000 ? 301 ARG A CG  1 
ATOM   2058 C CD  . ARG A 1 301 ? 21.07000 -10.24900 151.30900 1.000 8.74000  ? 301 ARG A CD  1 
ATOM   2059 N NE  . ARG A 1 301 ? 20.99700 -10.12500 152.75900 1.000 35.03000 ? 301 ARG A NE  1 
ATOM   2060 C CZ  . ARG A 1 301 ? 19.93400 -10.30600 153.51700 1.000 16.84000 ? 301 ARG A CZ  1 
ATOM   2061 N NH1 . ARG A 1 301 ? 18.97100 -11.13900 153.16100 1.000 19.27000 ? 301 ARG A NH1 1 
ATOM   2062 N NH2 . ARG A 1 301 ? 19.87400 -9.66700  154.65600 1.000 19.45000 ? 301 ARG A NH2 1 
ATOM   2063 N N   . GLY A 1 302 ? 21.52300 -7.87300  146.21400 1.000 6.73000  ? 302 GLY A N   1 
ATOM   2064 C CA  . GLY A 1 302 ? 21.24700 -8.15900  144.81800 1.000 7.91000  ? 302 GLY A CA  1 
ATOM   2065 C C   . GLY A 1 302 ? 20.98700 -6.94800  143.95700 1.000 6.45000  ? 302 GLY A C   1 
ATOM   2066 O O   . GLY A 1 302 ? 20.45100 -7.09700  142.84900 1.000 6.44000  ? 302 GLY A O   1 
ATOM   2067 N N   . VAL A 1 303 ? 21.33300 -5.74600  144.43300 1.000 5.98000  ? 303 VAL A N   1 
ATOM   2068 C CA  . VAL A 1 303 ? 21.16400 -4.52400  143.65600 1.000 6.67000  ? 303 VAL A CA  1 
ATOM   2069 C C   . VAL A 1 303 ? 22.45700 -3.72200  143.70200 1.000 6.64000  ? 303 VAL A C   1 
ATOM   2070 O O   . VAL A 1 303 ? 23.33200 -3.94600  144.54400 1.000 6.73000  ? 303 VAL A O   1 
ATOM   2071 C CB  . VAL A 1 303 ? 19.98200 -3.64700  144.14200 1.000 9.32000  ? 303 VAL A CB  1 
ATOM   2072 C CG1 . VAL A 1 303 ? 18.64700 -4.38700  143.96900 1.000 10.42000 ? 303 VAL A CG1 1 
ATOM   2073 C CG2 . VAL A 1 303 ? 20.19500 -3.20500  145.59300 1.000 8.78000  ? 303 VAL A CG2 1 
ATOM   2074 N N   . THR A 1 304 ? 22.55400 -2.77200  142.77100 1.000 6.64000  ? 304 THR A N   1 
ATOM   2075 C CA  . THR A 1 304 ? 23.74600 -1.97400  142.52100 1.000 5.52000  ? 304 THR A CA  1 
ATOM   2076 C C   . THR A 1 304 ? 23.67500 -0.61500  143.21200 1.000 6.70000  ? 304 THR A C   1 
ATOM   2077 O O   . THR A 1 304 ? 22.64000 -0.19100  143.72900 1.000 5.94000  ? 304 THR A O   1 
ATOM   2078 C CB  . THR A 1 304 ? 23.91000 -1.72700  141.01800 1.000 6.44000  ? 304 THR A CB  1 
ATOM   2079 O OG1 . THR A 1 304 ? 22.72900 -1.07600  140.53200 1.000 7.34000  ? 304 THR A OG1 1 
ATOM   2080 C CG2 . THR A 1 304 ? 24.12100 -3.03100  140.24300 1.000 6.63000  ? 304 THR A CG2 1 
ATOM   2081 N N   . HIS A 1 305 ? 24.80300 0.09500   143.15200 1.000 5.42000  ? 305 HIS A N   1 
ATOM   2082 C CA  . HIS A 1 305 ? 24.82800 1.54300   143.32400 1.000 5.73000  ? 305 HIS A CA  1 
ATOM   2083 C C   . HIS A 1 305 ? 23.70200 2.19200   142.52100 1.000 7.62000  ? 305 HIS A C   1 
ATOM   2084 O O   . HIS A 1 305 ? 23.32800 1.68200   141.46100 1.000 7.94000  ? 305 HIS A O   1 
ATOM   2085 C CB  . HIS A 1 305 ? 26.17900 2.08900   142.85500 1.000 7.64000  ? 305 HIS A CB  1 
ATOM   2086 C CG  . HIS A 1 305 ? 26.52800 3.42400   143.42700 1.000 9.07000  ? 305 HIS A CG  1 
ATOM   2087 N ND1 . HIS A 1 305 ? 27.06200 3.57300   144.68800 1.000 8.34000  ? 305 HIS A ND1 1 
ATOM   2088 C CD2 . HIS A 1 305 ? 26.45400 4.66900   142.89700 1.000 11.14000 ? 305 HIS A CD2 1 
ATOM   2089 C CE1 . HIS A 1 305 ? 27.28500 4.85700   144.91900 1.000 10.21000 ? 305 HIS A CE1 1 
ATOM   2090 N NE2 . HIS A 1 305 ? 26.92500 5.54300   143.84900 1.000 10.27000 ? 305 HIS A NE2 1 
ATOM   2091 N N   . SER A 1 306 ? 23.16500 3.30800   143.01900 1.000 6.77000  ? 306 SER A N   1 
ATOM   2092 C CA  . SER A 1 306 ? 22.12900 4.12800   142.37900 1.000 7.62000  ? 306 SER A CA  1 
ATOM   2093 C C   . SER A 1 306 ? 20.73800 3.50200   142.42700 1.000 7.73000  ? 306 SER A C   1 
ATOM   2094 O O   . SER A 1 306 ? 19.83200 4.00000   141.74400 1.000 7.78000  ? 306 SER A O   1 
ATOM   2095 C CB  . SER A 1 306 ? 22.47000 4.45900   140.91700 1.000 11.74000 ? 306 SER A CB  1 
ATOM   2096 O OG  . SER A 1 306 ? 23.68500 5.20000   140.81200 1.000 13.88000 ? 306 SER A OG  1 
ATOM   2097 N N   . PHE A 1 307 ? 20.52300 2.45100   143.23700 1.000 7.34000  ? 307 PHE A N   1 
ATOM   2098 C CA  . PHE A 1 307 ? 19.26100 1.71300   143.16700 1.000 6.79000  ? 307 PHE A CA  1 
ATOM   2099 C C   . PHE A 1 307 ? 18.05300 2.57500   143.53900 1.000 8.84000  ? 307 PHE A C   1 
ATOM   2100 O O   . PHE A 1 307 ? 16.93300 2.27200   143.11300 1.000 8.16000  ? 307 PHE A O   1 
ATOM   2101 C CB  . PHE A 1 307 ? 19.31800 0.44900   144.05100 1.000 6.03000  ? 307 PHE A CB  1 
ATOM   2102 C CG  . PHE A 1 307 ? 19.25600 0.71700   145.54800 1.000 9.66000  ? 307 PHE A CG  1 
ATOM   2103 C CD1 . PHE A 1 307 ? 18.04600 0.97800   146.18700 1.000 6.95000  ? 307 PHE A CD1 1 
ATOM   2104 C CD2 . PHE A 1 307 ? 20.40800 0.66900   146.31500 1.000 10.13000 ? 307 PHE A CD2 1 
ATOM   2105 C CE1 . PHE A 1 307 ? 17.98700 1.21900   147.55900 1.000 8.59000  ? 307 PHE A CE1 1 
ATOM   2106 C CE2 . PHE A 1 307 ? 20.36600 0.90700   147.69800 1.000 8.67000  ? 307 PHE A CE2 1 
ATOM   2107 C CZ  . PHE A 1 307 ? 19.15400 1.18000   148.31700 1.000 10.63000 ? 307 PHE A CZ  1 
ATOM   2108 N N   . THR A 1 308 ? 18.25500 3.63700   144.31800 1.000 6.65000  ? 308 THR A N   1 
ATOM   2109 C CA  . THR A 1 308 ? 17.14900 4.50700   144.70600 1.000 7.95000  ? 308 THR A CA  1 
ATOM   2110 C C   . THR A 1 308 ? 16.53800 5.22400   143.52100 1.000 8.89000  ? 308 THR A C   1 
ATOM   2111 O O   . THR A 1 308 ? 15.43900 5.76600   143.64500 1.000 8.83000  ? 308 THR A O   1 
ATOM   2112 C CB  . THR A 1 308 ? 17.61600 5.56200   145.71100 1.000 8.94000  ? 308 THR A CB  1 
ATOM   2113 O OG1 . THR A 1 308 ? 18.80300 6.19300   145.20700 1.000 10.62000 ? 308 THR A OG1 1 
ATOM   2114 C CG2 . THR A 1 308 ? 17.91000 4.91900   147.05700 1.000 7.90000  ? 308 THR A CG2 1 
ATOM   2115 N N   . ASN A 1 309 ? 17.23300 5.27800   142.38900 1.000 6.77000  ? 309 ASN A N   1 
ATOM   2116 C CA  . ASN A 1 309 ? 16.73500 5.99200   141.22600 1.000 7.26000  ? 309 ASN A CA  1 
ATOM   2117 C C   . ASN A 1 309 ? 16.43600 5.05300   140.06200 1.000 7.11000  ? 309 ASN A C   1 
ATOM   2118 O O   . ASN A 1 309 ? 16.32500 5.51100   138.92200 1.000 8.12000  ? 309 ASN A O   1 
ATOM   2119 C CB  . ASN A 1 309 ? 17.72800 7.08500   140.81400 1.000 8.08000  ? 309 ASN A CB  1 
ATOM   2120 C CG  . ASN A 1 309 ? 17.97300 8.09500   141.93100 1.000 10.86000 ? 309 ASN A CG  1 
ATOM   2121 O OD1 . ASN A 1 309 ? 18.79600 7.86300   142.81700 1.000 12.15000 ? 309 ASN A OD1 1 
ATOM   2122 N ND2 . ASN A 1 309 ? 17.24100 9.21400   141.90400 1.000 11.85000 ? 309 ASN A ND2 1 
ATOM   2123 N N   . LEU A 1 310 ? 16.25800 3.75300   140.33800 1.000 6.61000  ? 310 LEU A N   1 
ATOM   2124 C CA  . LEU A 1 310 ? 15.95300 2.75000   139.32000 1.000 6.13000  ? 310 LEU A CA  1 
ATOM   2125 C C   . LEU A 1 310 ? 14.57700 2.12300   139.52700 1.000 9.01000  ? 310 LEU A C   1 
ATOM   2126 O O   . LEU A 1 310 ? 14.33100 0.99700   139.09400 1.000 8.17000  ? 310 LEU A O   1 
ATOM   2127 C CB  . LEU A 1 310 ? 17.01800 1.64900   139.31000 1.000 7.80000  ? 310 LEU A CB  1 
ATOM   2128 C CG  . LEU A 1 310 ? 18.48500 2.08900   139.26300 1.000 9.07000  ? 310 LEU A CG  1 
ATOM   2129 C CD1 . LEU A 1 310 ? 19.41600 0.87000   139.35500 1.000 9.14000  ? 310 LEU A CD1 1 
ATOM   2130 C CD2 . LEU A 1 310 ? 18.75700 2.87800   137.99300 1.000 10.12000 ? 310 LEU A CD2 1 
ATOM   2131 N N   . ARG A 1 311 ? 13.68700 2.82300   140.22100 1.000 6.87000  ? 311 ARG A N   1 
ATOM   2132 C CA  . ARG A 1 311 ? 12.43500 2.18700   140.71700 1.000 7.92000  ? 311 ARG A CA  1 
ATOM   2133 C C   . ARG A 1 311 ? 11.38200 1.85500   139.65500 1.000 9.12000  ? 311 ARG A C   1 
ATOM   2134 O O   . ARG A 1 311 ? 10.41300 1.20600   140.01400 1.000 9.83000  ? 311 ARG A O   1 
ATOM   2135 C CB  . ARG A 1 311 ? 11.81300 3.11500   141.75300 1.000 10.65000 ? 311 ARG A CB  1 
ATOM   2136 C CG  . ARG A 1 311 ? 12.43700 3.05100   143.13400 1.000 9.15000  ? 311 ARG A CG  1 
ATOM   2137 C CD  . ARG A 1 311 ? 12.97300 4.40900   143.43700 1.000 18.98000 ? 311 ARG A CD  1 
ATOM   2138 N NE  . ARG A 1 311 ? 12.14700 5.48300   143.99000 1.000 25.72000 ? 311 ARG A NE  1 
ATOM   2139 C CZ  . ARG A 1 311 ? 11.28400 6.27900   143.37400 1.000 9.38000  ? 311 ARG A CZ  1 
ATOM   2140 N NH1 . ARG A 1 311 ? 9.99700  6.03600   143.48100 1.000 11.41000 ? 311 ARG A NH1 1 
ATOM   2141 N NH2 . ARG A 1 311 ? 11.70000 7.34300   142.71200 1.000 12.81000 ? 311 ARG A NH2 1 
ATOM   2142 N N   . GLN A 1 312 ? 11.54600 2.36500   138.45200 1.000 8.26000  ? 312 GLN A N   1 
ATOM   2143 C CA  . GLN A 1 312 ? 10.62500 1.95700   137.39900 1.000 9.88000  ? 312 GLN A CA  1 
ATOM   2144 C C   . GLN A 1 312 ? 11.12700 0.71500   136.67600 1.000 10.03000 ? 312 GLN A C   1 
ATOM   2145 O O   . GLN A 1 312 ? 10.40000 -0.27700  136.54400 1.000 10.54000 ? 312 GLN A O   1 
ATOM   2146 C CB  . GLN A 1 312 ? 10.41400 3.09300   136.39300 1.000 9.83000  ? 312 GLN A CB  1 
ATOM   2147 C CG  . GLN A 1 312 ? 9.44100  2.74200   135.26200 1.000 13.39000 ? 312 GLN A CG  1 
ATOM   2148 C CD  . GLN A 1 312 ? 8.01900  2.60500   135.75700 1.000 19.31000 ? 312 GLN A CD  1 
ATOM   2149 O OE1 . GLN A 1 312 ? 7.60300  3.30800   136.67400 1.000 15.30000 ? 312 GLN A OE1 1 
ATOM   2150 N NE2 . GLN A 1 312 ? 7.25800  1.70300   135.14400 1.000 25.74000 ? 312 GLN A NE2 1 
ATOM   2151 N N   . MET A 1 313 ? 12.37000 0.74100   136.21500 1.000 11.23000 ? 313 MET A N   1 
ATOM   2152 C CA  . MET A 1 313 ? 12.87200 -0.37200  135.42600 1.000 11.57000 ? 313 MET A CA  1 
ATOM   2153 C C   . MET A 1 313 ? 13.41200 -1.51600  136.27500 1.000 12.20000 ? 313 MET A C   1 
ATOM   2154 O O   . MET A 1 313 ? 13.53300 -2.63900  135.76400 1.000 12.49000 ? 313 MET A O   1 
ATOM   2155 C CB  . MET A 1 313 ? 13.94000 0.12700   134.45700 1.000 10.05000 ? 313 MET A CB  1 
ATOM   2156 C CG  . MET A 1 313 ? 13.34400 1.03100   133.39300 1.000 17.55000 ? 313 MET A CG  1 
ATOM   2157 S SD  . MET A 1 313 ? 14.40300 1.10900   131.96300 1.000 37.07000 ? 313 MET A SD  1 
ATOM   2158 C CE  . MET A 1 313 ? 14.13900 -0.54400  131.31500 1.000 34.67000 ? 313 MET A CE  1 
ATOM   2159 N N   . VAL A 1 314 ? 13.72700 -1.26700  137.54500 1.000 10.30000 ? 314 VAL A N   1 
ATOM   2160 C CA  . VAL A 1 314 ? 14.06400 -2.32400  138.50000 1.000 9.49000  ? 314 VAL A CA  1 
ATOM   2161 C C   . VAL A 1 314 ? 13.04300 -2.21600  139.62700 1.000 8.96000  ? 314 VAL A C   1 
ATOM   2162 O O   . VAL A 1 314 ? 13.32200 -1.61500  140.67800 1.000 9.71000  ? 314 VAL A O   1 
ATOM   2163 C CB  . VAL A 1 314 ? 15.51200 -2.20900  139.00800 1.000 9.27000  ? 314 VAL A CB  1 
ATOM   2164 C CG1 . VAL A 1 314 ? 15.89100 -3.42900  139.85900 1.000 8.38000  ? 314 VAL A CG1 1 
ATOM   2165 C CG2 . VAL A 1 314 ? 16.48100 -2.05900  137.82300 1.000 9.85000  ? 314 VAL A CG2 1 
ATOM   2166 N N   . PRO A 1 315 ? 11.84400 -2.76500  139.43000 1.000 9.39000  ? 315 PRO A N   1 
ATOM   2167 C CA  . PRO A 1 315 ? 10.72900 -2.46300  140.34200 1.000 9.79000  ? 315 PRO A CA  1 
ATOM   2168 C C   . PRO A 1 315 ? 10.98100 -2.87100  141.77700 1.000 10.63000 ? 315 PRO A C   1 
ATOM   2169 O O   . PRO A 1 315 ? 10.40600 -2.25800  142.68800 1.000 10.60000 ? 315 PRO A O   1 
ATOM   2170 C CB  . PRO A 1 315 ? 9.55900  -3.25300  139.73300 1.000 13.42000 ? 315 PRO A CB  1 
ATOM   2171 C CG  . PRO A 1 315 ? 9.93600  -3.44400  138.29600 1.000 13.45000 ? 315 PRO A CG  1 
ATOM   2172 C CD  . PRO A 1 315 ? 11.42500 -3.56400  138.26500 1.000 11.14000 ? 315 PRO A CD  1 
ATOM   2173 N N   . SER A 1 316 ? 11.81200 -3.88500  142.01500 1.000 8.72000  ? 316 SER A N   1 
ATOM   2174 C CA  . SER A 1 316 ? 12.06200 -4.29700  143.39500 1.000 9.51000  ? 316 SER A CA  1 
ATOM   2175 C C   . SER A 1 316 ? 12.79300 -3.23200  144.21100 1.000 9.41000  ? 316 SER A C   1 
ATOM   2176 O O   . SER A 1 316 ? 12.78400 -3.31400  145.45000 1.000 8.55000  ? 316 SER A O   1 
ATOM   2177 C CB  . SER A 1 316 ? 12.85200 -5.61100  143.41300 1.000 11.40000 ? 316 SER A CB  1 
ATOM   2178 O OG  . SER A 1 316 ? 14.17500 -5.42100  142.92500 1.000 10.41000 ? 316 SER A OG  1 
ATOM   2179 N N   . THR A 1 317 ? 13.39800 -2.22500  143.56600 1.000 8.10000  ? 317 THR A N   1 
ATOM   2180 C CA  . THR A 1 317 ? 14.08800 -1.18800  144.33100 1.000 7.91000  ? 317 THR A CA  1 
ATOM   2181 C C   . THR A 1 317 ? 13.12000 -0.23200  145.01800 1.000 7.44000  ? 317 THR A C   1 
ATOM   2182 O O   . THR A 1 317 ? 13.52000 0.45100   145.96100 1.000 7.71000  ? 317 THR A O   1 
ATOM   2183 C CB  . THR A 1 317 ? 15.06800 -0.38900  143.45200 1.000 8.26000  ? 317 THR A CB  1 
ATOM   2184 O OG1 . THR A 1 317 ? 14.37800 0.22400   142.35400 1.000 8.41000  ? 317 THR A OG1 1 
ATOM   2185 C CG2 . THR A 1 317 ? 16.18000 -1.29400  142.92000 1.000 8.91000  ? 317 THR A CG2 1 
ATOM   2186 N N   . GLN A 1 318 ? 11.85800 -0.17100  144.58800 1.000 6.86000  ? 318 GLN A N   1 
ATOM   2187 C CA  . GLN A 1 318 ? 10.88100 0.60800   145.34500 1.000 8.00000  ? 318 GLN A CA  1 
ATOM   2188 C C   . GLN A 1 318 ? 10.68400 0.02500   146.73900 1.000 8.11000  ? 318 GLN A C   1 
ATOM   2189 O O   . GLN A 1 318 ? 10.59200 0.76900   147.72300 1.000 8.15000  ? 318 GLN A O   1 
ATOM   2190 C CB  . GLN A 1 318 ? 9.54800  0.68000   144.59200 1.000 9.60000  ? 318 GLN A CB  1 
ATOM   2191 C CG  . GLN A 1 318 ? 8.43700  1.37800   145.37100 1.000 8.13000  ? 318 GLN A CG  1 
ATOM   2192 C CD  . GLN A 1 318 ? 8.60100  2.89100   145.41000 1.000 10.03000 ? 318 GLN A CD  1 
ATOM   2193 O OE1 . GLN A 1 318 ? 9.29900  3.47000   144.57300 1.000 11.49000 ? 318 GLN A OE1 1 
ATOM   2194 N NE2 . GLN A 1 318 ? 7.95500  3.53600   146.38200 1.000 9.31000  ? 318 GLN A NE2 1 
ATOM   2195 N N   . ALA A 1 319 ? 10.62200 -1.30800  146.84300 1.000 7.71000  ? 319 ALA A N   1 
ATOM   2196 C CA  . ALA A 1 319 ? 10.49300 -1.94800  148.15000 1.000 9.65000  ? 319 ALA A CA  1 
ATOM   2197 C C   . ALA A 1 319 ? 11.72200 -1.68900  149.01600 1.000 8.18000  ? 319 ALA A C   1 
ATOM   2198 O O   . ALA A 1 319 ? 11.60400 -1.50900  150.23700 1.000 8.18000  ? 319 ALA A O   1 
ATOM   2199 C CB  . ALA A 1 319 ? 10.26000 -3.44800  147.97600 1.000 12.23000 ? 319 ALA A CB  1 
ATOM   2200 N N   . ASP A 1 320 ? 12.90900 -1.65000  148.40000 1.000 8.27000  ? 320 ASP A N   1 
ATOM   2201 C CA  . ASP A 1 320 ? 14.11700 -1.29500  149.14300 1.000 6.96000  ? 320 ASP A CA  1 
ATOM   2202 C C   . ASP A 1 320 ? 14.00200 0.10100   149.72600 1.000 8.25000  ? 320 ASP A C   1 
ATOM   2203 O O   . ASP A 1 320 ? 14.33000 0.32200   150.89500 1.000 6.11000  ? 320 ASP A O   1 
ATOM   2204 C CB  . ASP A 1 320 ? 15.36100 -1.35600  148.25400 1.000 10.12000 ? 320 ASP A CB  1 
ATOM   2205 C CG  . ASP A 1 320 ? 15.61100 -2.72900  147.67700 1.000 14.50000 ? 320 ASP A CG  1 
ATOM   2206 O OD1 . ASP A 1 320 ? 15.37800 -3.74200  148.38300 1.000 13.97000 ? 320 ASP A OD1 1 
ATOM   2207 O OD2 . ASP A 1 320 ? 16.07400 -2.77600  146.51500 1.000 11.76000 ? 320 ASP A OD2 1 
ATOM   2208 N N   . LEU A 1 321 ? 13.58600 1.07000   148.90400 1.000 6.22000  ? 321 LEU A N   1 
ATOM   2209 C CA  . LEU A 1 321 ? 13.41300 2.43400   149.39600 1.000 7.21000  ? 321 LEU A CA  1 
ATOM   2210 C C   . LEU A 1 321 ? 12.41200 2.47800   150.54000 1.000 7.66000  ? 321 LEU A C   1 
ATOM   2211 O O   . LEU A 1 321 ? 12.61500 3.19100   151.53000 1.000 6.08000  ? 321 LEU A O   1 
ATOM   2212 C CB  . LEU A 1 321 ? 12.95700 3.34800   148.25800 1.000 7.57000  ? 321 LEU A CB  1 
ATOM   2213 C CG  . LEU A 1 321 ? 12.66000 4.80400   148.63800 1.000 8.83000  ? 321 LEU A CG  1 
ATOM   2214 C CD1 . LEU A 1 321 ? 13.88100 5.48400   149.25900 1.000 10.46000 ? 321 LEU A CD1 1 
ATOM   2215 C CD2 . LEU A 1 321 ? 12.15700 5.58800   147.43300 1.000 9.43000  ? 321 LEU A CD2 1 
ATOM   2216 N N   . GLU A 1 322 ? 11.32900 1.70900   150.43500 1.000 6.22000  ? 322 GLU A N   1 
ATOM   2217 C CA  . GLU A 1 322 ? 10.32200 1.75800   151.48700 1.000 6.48000  ? 322 GLU A CA  1 
ATOM   2218 C C   . GLU A 1 322 ? 10.84700 1.19400   152.80300 1.000 6.58000  ? 322 GLU A C   1 
ATOM   2219 O O   . GLU A 1 322 ? 10.38900 1.61400   153.87300 1.000 6.05000  ? 322 GLU A O   1 
ATOM   2220 C CB  . GLU A 1 322 ? 9.05600  1.03200   151.03600 1.000 8.23000  ? 322 GLU A CB  1 
ATOM   2221 C CG  . GLU A 1 322 ? 8.31300  1.85800   149.97300 1.000 11.15000 ? 322 GLU A CG  1 
ATOM   2222 C CD  . GLU A 1 322 ? 7.17500  1.11300   149.30600 1.000 20.40000 ? 322 GLU A CD  1 
ATOM   2223 O OE1 . GLU A 1 322 ? 6.89600  -0.04100  149.70000 1.000 22.06000 ? 322 GLU A OE1 1 
ATOM   2224 O OE2 . GLU A 1 322 ? 6.56100  1.69300   148.38000 1.000 15.35000 ? 322 GLU A OE2 1 
ATOM   2225 N N   . ARG A 1 323 ? 11.79900 0.25900   152.75100 1.000 4.99000  ? 323 ARG A N   1 
ATOM   2226 C CA  . ARG A 1 323 ? 12.42100 -0.22100  153.98500 1.000 7.10000  ? 323 ARG A CA  1 
ATOM   2227 C C   . ARG A 1 323 ? 13.25400 0.87400   154.64000 1.000 5.29000  ? 323 ARG A C   1 
ATOM   2228 O O   . ARG A 1 323 ? 13.27200 0.98700   155.86900 1.000 4.48000  ? 323 ARG A O   1 
ATOM   2229 C CB  . ARG A 1 323 ? 13.29800 -1.45000  153.72000 1.000 5.94000  ? 323 ARG A CB  1 
ATOM   2230 C CG  . ARG A 1 323 ? 12.54800 -2.69600  153.25700 1.000 10.67000 ? 323 ARG A CG  1 
ATOM   2231 C CD  . ARG A 1 323 ? 13.51100 -3.86700  153.04500 1.000 7.53000  ? 323 ARG A CD  1 
ATOM   2232 N NE  . ARG A 1 323 ? 14.16300 -4.29100  154.28700 1.000 7.56000  ? 323 ARG A NE  1 
ATOM   2233 C CZ  . ARG A 1 323 ? 15.43900 -4.66200  154.37400 1.000 10.04000 ? 323 ARG A CZ  1 
ATOM   2234 N NH1 . ARG A 1 323 ? 16.20900 -4.65900  153.29200 1.000 9.31000  ? 323 ARG A NH1 1 
ATOM   2235 N NH2 . ARG A 1 323 ? 15.94700 -5.04400  155.54200 1.000 7.76000  ? 323 ARG A NH2 1 
ATOM   2236 N N   . VAL A 1 324 ? 13.96800 1.67500   153.83800 1.000 4.93000  ? 324 VAL A N   1 
ATOM   2237 C CA  . VAL A 1 324 ? 14.71200 2.81400   154.38700 1.000 4.77000  ? 324 VAL A CA  1 
ATOM   2238 C C   . VAL A 1 324 ? 13.75400 3.81500   155.02400 1.000 4.81000  ? 324 VAL A C   1 
ATOM   2239 O O   . VAL A 1 324 ? 14.00000 4.32500   156.12400 1.000 4.21000  ? 324 VAL A O   1 
ATOM   2240 C CB  . VAL A 1 324 ? 15.57300 3.48900   153.29900 1.000 4.65000  ? 324 VAL A CB  1 
ATOM   2241 C CG1 . VAL A 1 324 ? 16.35400 4.69300   153.90100 1.000 4.86000  ? 324 VAL A CG1 1 
ATOM   2242 C CG2 . VAL A 1 324 ? 16.51100 2.48200   152.64900 1.000 7.50000  ? 324 VAL A CG2 1 
ATOM   2243 N N   . ILE A 1 325 ? 12.64300 4.10400   154.34800 1.000 4.21000  ? 325 ILE A N   1 
ATOM   2244 C CA  . ILE A 1 325 ? 11.62600 4.99400   154.91500 1.000 5.40000  ? 325 ILE A CA  1 
ATOM   2245 C C   . ILE A 1 325 ? 11.18100 4.48800   156.27900 1.000 5.15000  ? 325 ILE A C   1 
ATOM   2246 O O   . ILE A 1 325 ? 11.08900 5.25200   157.25100 1.000 6.02000  ? 325 ILE A O   1 
ATOM   2247 C CB  . ILE A 1 325 ? 10.42800 5.10500   153.95400 1.000 4.99000  ? 325 ILE A CB  1 
ATOM   2248 C CG1 . ILE A 1 325 ? 10.86200 5.78800   152.65700 1.000 5.59000  ? 325 ILE A CG1 1 
ATOM   2249 C CG2 . ILE A 1 325 ? 9.25900  5.85400   154.61400 1.000 6.52000  ? 325 ILE A CG2 1 
ATOM   2250 C CD1 . ILE A 1 325 ? 11.21300 7.25900   152.82900 1.000 7.30000  ? 325 ILE A CD1 1 
ATOM   2251 N N   . ALA A 1 326 ? 10.86900 3.19400   156.36300 1.000 5.10000  ? 326 ALA A N   1 
ATOM   2252 C CA  . ALA A 1 326 ? 10.37700 2.64100   157.62300 1.000 5.94000  ? 326 ALA A CA  1 
ATOM   2253 C C   . ALA A 1 326 ? 11.44000 2.72600   158.71100 1.000 6.91000  ? 326 ALA A C   1 
ATOM   2254 O O   . ALA A 1 326 ? 11.12200 2.95100   159.88700 1.000 5.33000  ? 326 ALA A O   1 
ATOM   2255 C CB  . ALA A 1 326 ? 9.92300  1.19700   157.42100 1.000 7.85000  ? 326 ALA A CB  1 
ATOM   2256 N N   . ALA A 1 327 ? 12.71100 2.55200   158.33600 1.000 5.30000  ? 327 ALA A N   1 
ATOM   2257 C CA  . ALA A 1 327 ? 13.79200 2.72800   159.30300 1.000 5.60000  ? 327 ALA A CA  1 
ATOM   2258 C C   . ALA A 1 327 ? 13.86300 4.16900   159.79000 1.000 5.42000  ? 327 ALA A C   1 
ATOM   2259 O O   . ALA A 1 327 ? 14.09100 4.42400   160.98200 1.000 5.49000  ? 327 ALA A O   1 
ATOM   2260 C CB  . ALA A 1 327 ? 15.12100 2.30200   158.67500 1.000 4.94000  ? 327 ALA A CB  1 
ATOM   2261 N N   . MET A 1 328 ? 13.67200 5.12700   158.88000 1.000 4.14000  ? 328 MET A N   1 
ATOM   2262 C CA  . MET A 1 328 ? 13.68300 6.53500   159.27000 1.000 5.12000  ? 328 MET A CA  1 
ATOM   2263 C C   . MET A 1 328 ? 12.54400 6.84400   160.23200 1.000 6.94000  ? 328 MET A C   1 
ATOM   2264 O O   . MET A 1 328 ? 12.73800 7.54400   161.23300 1.000 5.49000  ? 328 MET A O   1 
ATOM   2265 C CB  . MET A 1 328 ? 13.59200 7.42200   158.02300 1.000 4.37000  ? 328 MET A CB  1 
ATOM   2266 C CG  . MET A 1 328 ? 14.81800 7.31700   157.13700 1.000 4.87000  ? 328 MET A CG  1 
ATOM   2267 S SD  . MET A 1 328 ? 14.57200 8.06800   155.52200 1.000 7.15000  ? 328 MET A SD  1 
ATOM   2268 C CE  . MET A 1 328 ? 14.27800 9.77800   155.97600 1.000 9.10000  ? 328 MET A CE  1 
ATOM   2269 N N   . GLN A 1 329 ? 11.35000 6.32400   159.95100 1.000 5.09000  ? 329 GLN A N   1 
ATOM   2270 C CA  . GLN A 1 329 ? 10.21900 6.57200   160.84300 1.000 7.03000  ? 329 GLN A CA  1 
ATOM   2271 C C   . GLN A 1 329 ? 10.44300 5.93400   162.20800 1.000 6.55000  ? 329 GLN A C   1 
ATOM   2272 O O   . GLN A 1 329 ? 10.10900 6.53100   163.24300 1.000 6.82000  ? 329 GLN A O   1 
ATOM   2273 C CB  . GLN A 1 329 ? 8.92900  6.04700   160.21000 1.000 8.58000  ? 329 GLN A CB  1 
ATOM   2274 C CG  . GLN A 1 329 ? 8.53200  6.81800   158.95100 1.000 10.03000 ? 329 GLN A CG  1 
ATOM   2275 C CD  . GLN A 1 329 ? 7.50600  6.08300   158.13000 1.000 20.79000 ? 329 GLN A CD  1 
ATOM   2276 O OE1 . GLN A 1 329 ? 7.47200  4.84500   158.12200 1.000 23.49000 ? 329 GLN A OE1 1 
ATOM   2277 N NE2 . GLN A 1 329 ? 6.65300  6.83500   157.42700 1.000 22.95000 ? 329 GLN A NE2 1 
ATOM   2278 N N   . PHE A 1 330 ? 11.01800 4.72400   162.23000 1.000 5.87000  ? 330 PHE A N   1 
ATOM   2279 C CA  . PHE A 1 330 ? 11.32900 4.07400   163.49900 1.000 7.00000  ? 330 PHE A CA  1 
ATOM   2280 C C   . PHE A 1 330 ? 12.32200 4.90600   164.31000 1.000 6.82000  ? 330 PHE A C   1 
ATOM   2281 O O   . PHE A 1 330 ? 12.11300 5.15600   165.50300 1.000 6.81000  ? 330 PHE A O   1 
ATOM   2282 C CB  . PHE A 1 330 ? 11.87500 2.65700   163.25700 1.000 6.64000  ? 330 PHE A CB  1 
ATOM   2283 C CG  . PHE A 1 330 ? 12.87800 2.22200   164.29300 1.000 10.29000 ? 330 PHE A CG  1 
ATOM   2284 C CD1 . PHE A 1 330 ? 12.48000 2.01600   165.61600 1.000 7.50000  ? 330 PHE A CD1 1 
ATOM   2285 C CD2 . PHE A 1 330 ? 14.21000 2.04400   163.96100 1.000 7.63000  ? 330 PHE A CD2 1 
ATOM   2286 C CE1 . PHE A 1 330 ? 13.39000 1.63600   166.58800 1.000 6.55000  ? 330 PHE A CE1 1 
ATOM   2287 C CE2 . PHE A 1 330 ? 15.13200 1.67300   164.93600 1.000 9.57000  ? 330 PHE A CE2 1 
ATOM   2288 C CZ  . PHE A 1 330 ? 14.72000 1.47100   166.25200 1.000 7.98000  ? 330 PHE A CZ  1 
ATOM   2289 N N   . MET A 1 331 ? 13.41000 5.35300   163.67900 1.000 7.45000  ? 331 MET A N   1 
ATOM   2290 C CA  . MET A 1 331 ? 14.41400 6.11100   164.42500 1.000 8.12000  ? 331 MET A CA  1 
ATOM   2291 C C   . MET A 1 331 ? 13.84400 7.42600   164.96200 1.000 7.30000  ? 331 MET A C   1 
ATOM   2292 O O   . MET A 1 331 ? 14.08900 7.79000   166.11900 1.000 8.10000  ? 331 MET A O   1 
ATOM   2293 C CB  . MET A 1 331 ? 15.63800 6.36200   163.54300 1.000 5.41000  ? 331 MET A CB  1 
ATOM   2294 C CG  . MET A 1 331 ? 16.46300 5.09400   163.27000 1.000 6.85000  ? 331 MET A CG  1 
ATOM   2295 S SD  . MET A 1 331 ? 17.29800 4.44600   164.74300 1.000 11.31000 ? 331 MET A SD  1 
ATOM   2296 C CE  . MET A 1 331 ? 18.68900 5.56900   164.88600 1.000 14.84000 ? 331 MET A CE  1 
ATOM   2297 N N   . LEU A 1 332 ? 13.06800 8.14800   164.14500 1.000 5.55000  ? 332 LEU A N   1 
ATOM   2298 C CA  . LEU A 1 332 ? 12.55400 9.44600   164.57400 1.000 6.79000  ? 332 LEU A CA  1 
ATOM   2299 C C   . LEU A 1 332 ? 11.56300 9.31200   165.71700 1.000 6.50000  ? 332 LEU A C   1 
ATOM   2300 O O   . LEU A 1 332 ? 11.47800 10.20400  166.57400 1.000 7.77000  ? 332 LEU A O   1 
ATOM   2301 C CB  . LEU A 1 332 ? 11.87700 10.16800  163.40900 1.000 7.84000  ? 332 LEU A CB  1 
ATOM   2302 C CG  . LEU A 1 332 ? 12.80300 10.64100  162.29200 1.000 7.03000  ? 332 LEU A CG  1 
ATOM   2303 C CD1 . LEU A 1 332 ? 11.96300 11.12200  161.14200 1.000 8.71000  ? 332 LEU A CD1 1 
ATOM   2304 C CD2 . LEU A 1 332 ? 13.73100 11.75700  162.81200 1.000 8.51000  ? 332 LEU A CD2 1 
ATOM   2305 N N   . ALA A 1 333 ? 10.78600 8.23500   165.72300 1.000 6.39000  ? 333 ALA A N   1 
ATOM   2306 C CA  . ALA A 1 333 ? 9.76400  8.05300   166.74000 1.000 8.14000  ? 333 ALA A CA  1 
ATOM   2307 C C   . ALA A 1 333 ? 10.33300 7.50800   168.03600 1.000 11.39000 ? 333 ALA A C   1 
ATOM   2308 O O   . ALA A 1 333 ? 9.65200  7.56100   169.06800 1.000 9.57000  ? 333 ALA A O   1 
ATOM   2309 C CB  . ALA A 1 333 ? 8.67200  7.11900   166.22200 1.000 10.26000 ? 333 ALA A CB  1 
ATOM   2310 N N   . ASN A 1 334 ? 11.56500 7.01200   168.01400 1.000 7.61000  ? 334 ASN A N   1 
ATOM   2311 C CA  . ASN A 1 334 ? 12.14800 6.30800   169.15900 1.000 8.65000  ? 334 ASN A CA  1 
ATOM   2312 C C   . ASN A 1 334 ? 13.56000 6.80700   169.45100 1.000 9.82000  ? 334 ASN A C   1 
ATOM   2313 O O   . ASN A 1 334 ? 14.52200 6.02900   169.44100 1.000 9.36000  ? 334 ASN A O   1 
ATOM   2314 C CB  . ASN A 1 334 ? 12.13500 4.80400   168.89200 1.000 7.60000  ? 334 ASN A CB  1 
ATOM   2315 C CG  . ASN A 1 334 ? 10.72300 4.25900   168.74700 1.000 12.13000 ? 334 ASN A CG  1 
ATOM   2316 O OD1 . ASN A 1 334 ? 10.04700 3.99400   169.74800 1.000 13.21000 ? 334 ASN A OD1 1 
ATOM   2317 N ND2 . ASN A 1 334 ? 10.26000 4.10200   167.50200 1.000 5.84000  ? 334 ASN A ND2 1 
ATOM   2318 N N   . PRO A 1 335 ? 13.72400 8.10100   169.72700 1.000 10.13000 ? 335 PRO A N   1 
ATOM   2319 C CA  . PRO A 1 335 ? 15.07000 8.63000   169.98800 1.000 10.15000 ? 335 PRO A CA  1 
ATOM   2320 C C   . PRO A 1 335 ? 15.63400 8.13200   171.31100 1.000 10.63000 ? 335 PRO A C   1 
ATOM   2321 O O   . PRO A 1 335 ? 14.91200 7.80300   172.25900 1.000 11.47000 ? 335 PRO A O   1 
ATOM   2322 C CB  . PRO A 1 335 ? 14.86000 10.14700  170.02300 1.000 11.92000 ? 335 PRO A CB  1 
ATOM   2323 C CG  . PRO A 1 335 ? 13.44900 10.31600  170.44600 1.000 15.11000 ? 335 PRO A CG  1 
ATOM   2324 C CD  . PRO A 1 335 ? 12.68800 9.14400   169.86700 1.000 10.69000 ? 335 PRO A CD  1 
ATOM   2325 N N   . ALA A 1 336 ? 16.96500 8.11200   171.36300 1.000 9.96000  ? 336 ALA A N   1 
ATOM   2326 C CA  . ALA A 1 336 ? 17.71400 7.65000   172.52700 1.000 11.88000 ? 336 ALA A CA  1 
ATOM   2327 C C   . ALA A 1 336 ? 17.31600 8.35400   173.82500 1.000 23.89000 ? 336 ALA A C   1 
ATOM   2328 O O   . ALA A 1 336 ? 17.20000 9.58200   173.87000 1.000 26.50000 ? 336 ALA A O   1 
ATOM   2329 C CB  . ALA A 1 336 ? 19.21700 7.82700   172.27000 1.000 11.42000 ? 336 ALA A CB  1 
ATOM   2330 N N   . THR B 1 24  ? 35.43600 10.26500  183.73000 1.000 37.75000 ? 24  THR B N   1 
ATOM   2331 C CA  . THR B 1 24  ? 34.27000 9.53600   184.21800 1.000 26.80000 ? 24  THR B CA  1 
ATOM   2332 C C   . THR B 1 24  ? 33.29900 9.23800   183.08800 1.000 23.87000 ? 24  THR B C   1 
ATOM   2333 O O   . THR B 1 24  ? 32.82300 10.15600  182.41500 1.000 23.99000 ? 24  THR B O   1 
ATOM   2334 C CB  . THR B 1 24  ? 33.52000 10.31800  185.30600 1.000 32.33000 ? 24  THR B CB  1 
ATOM   2335 O OG1 . THR B 1 24  ? 34.44600 10.76300  186.30400 1.000 38.84000 ? 24  THR B OG1 1 
ATOM   2336 C CG2 . THR B 1 24  ? 32.46200 9.43500   185.95300 1.000 29.20000 ? 24  THR B CG2 1 
ATOM   2337 N N   . PRO B 1 25  ? 32.99600 7.95900   182.87900 1.000 22.49000 ? 25  PRO B N   1 
ATOM   2338 C CA  . PRO B 1 25  ? 32.05700 7.59900   181.80900 1.000 16.33000 ? 25  PRO B CA  1 
ATOM   2339 C C   . PRO B 1 25  ? 30.67900 8.18300   182.08300 1.000 15.14000 ? 25  PRO B C   1 
ATOM   2340 O O   . PRO B 1 25  ? 30.26200 8.34900   183.23300 1.000 14.37000 ? 25  PRO B O   1 
ATOM   2341 C CB  . PRO B 1 25  ? 32.03800 6.06500   181.84600 1.000 16.19000 ? 25  PRO B CB  1 
ATOM   2342 C CG  . PRO B 1 25  ? 33.29400 5.67800   182.59100 1.000 22.95000 ? 25  PRO B CG  1 
ATOM   2343 C CD  . PRO B 1 25  ? 33.50100 6.77500   183.59500 1.000 24.14000 ? 25  PRO B CD  1 
ATOM   2344 N N   . TYR B 1 26  ? 29.96600 8.50000   181.00700 1.000 12.87000 ? 26  TYR B N   1 
ATOM   2345 C CA  . TYR B 1 26  ? 28.63000 9.05200   181.16100 1.000 11.57000 ? 26  TYR B CA  1 
ATOM   2346 C C   . TYR B 1 26  ? 27.70900 8.03600   181.82500 1.000 11.77000 ? 26  TYR B C   1 
ATOM   2347 O O   . TYR B 1 26  ? 27.63800 6.87800   181.40300 1.000 10.97000 ? 26  TYR B O   1 
ATOM   2348 C CB  . TYR B 1 26  ? 28.07100 9.46100   179.80400 1.000 9.80000  ? 26  TYR B CB  1 
ATOM   2349 C CG  . TYR B 1 26  ? 26.59200 9.76500   179.83600 1.000 11.45000 ? 26  TYR B CG  1 
ATOM   2350 C CD1 . TYR B 1 26  ? 26.10500 10.88300  180.50200 1.000 14.37000 ? 26  TYR B CD1 1 
ATOM   2351 C CD2 . TYR B 1 26  ? 25.68000 8.91900   179.21600 1.000 11.14000 ? 26  TYR B CD2 1 
ATOM   2352 C CE1 . TYR B 1 26  ? 24.74100 11.16200  180.54100 1.000 17.89000 ? 26  TYR B CE1 1 
ATOM   2353 C CE2 . TYR B 1 26  ? 24.32600 9.18600   179.24700 1.000 13.40000 ? 26  TYR B CE2 1 
ATOM   2354 C CZ  . TYR B 1 26  ? 23.85800 10.30600  179.90700 1.000 16.96000 ? 26  TYR B CZ  1 
ATOM   2355 O OH  . TYR B 1 26  ? 22.50300 10.56600  179.92400 1.000 21.17000 ? 26  TYR B OH  1 
ATOM   2356 N N   . ILE B 1 27  ? 27.00800 8.47000   182.87100 1.000 9.95000  ? 27  ILE B N   1 
ATOM   2357 C CA  . ILE B 1 27  ? 26.04200 7.62500   183.56700 1.000 9.44000  ? 27  ILE B CA  1 
ATOM   2358 C C   . ILE B 1 27  ? 24.79700 8.44900   183.87700 1.000 11.73000 ? 27  ILE B C   1 
ATOM   2359 O O   . ILE B 1 27  ? 24.89100 9.61900   184.26400 1.000 13.49000 ? 27  ILE B O   1 
ATOM   2360 C CB  . ILE B 1 27  ? 26.66100 7.01200   184.84300 1.000 11.60000 ? 27  ILE B CB  1 
ATOM   2361 C CG1 . ILE B 1 27  ? 25.66200 6.09600   185.55000 1.000 9.76000  ? 27  ILE B CG1 1 
ATOM   2362 C CG2 . ILE B 1 27  ? 27.18400 8.09500   185.78700 1.000 12.47000 ? 27  ILE B CG2 1 
ATOM   2363 C CD1 . ILE B 1 27  ? 26.33000 5.20100   186.59700 1.000 11.83000 ? 27  ILE B CD1 1 
ATOM   2364 N N   . ARG B 1 28  ? 23.62600 7.85100   183.67100 1.000 8.37000  ? 28  ARG B N   1 
ATOM   2365 C CA  . ARG B 1 28  ? 22.37800 8.53400   183.97200 1.000 9.18000  ? 28  ARG B CA  1 
ATOM   2366 C C   . ARG B 1 28  ? 22.21000 8.71300   185.47800 1.000 9.78000  ? 28  ARG B C   1 
ATOM   2367 O O   . ARG B 1 28  ? 22.67200 7.88200   186.26500 1.000 11.57000 ? 28  ARG B O   1 
ATOM   2368 C CB  . ARG B 1 28  ? 21.19200 7.74900   183.44300 1.000 9.01000  ? 28  ARG B CB  1 
ATOM   2369 C CG  . ARG B 1 28  ? 21.17000 7.61700   181.95300 1.000 7.91000  ? 28  ARG B CG  1 
ATOM   2370 C CD  . ARG B 1 28  ? 19.97300 6.78700   181.53200 1.000 10.63000 ? 28  ARG B CD  1 
ATOM   2371 N NE  . ARG B 1 28  ? 20.13400 6.35400   180.15100 1.000 9.38000  ? 28  ARG B NE  1 
ATOM   2372 C CZ  . ARG B 1 28  ? 19.33200 5.49700   179.53400 1.000 9.72000  ? 28  ARG B CZ  1 
ATOM   2373 N NH1 . ARG B 1 28  ? 18.29100 4.96900   180.17400 1.000 7.32000  ? 28  ARG B NH1 1 
ATOM   2374 N NH2 . ARG B 1 28  ? 19.57600 5.16600   178.27300 1.000 7.55000  ? 28  ARG B NH2 1 
ATOM   2375 N N   . PRO B 1 29  ? 21.52900 9.78200   185.90500 1.000 11.03000 ? 29  PRO B N   1 
ATOM   2376 C CA  . PRO B 1 29  ? 21.33100 9.97500   187.35100 1.000 14.70000 ? 29  PRO B CA  1 
ATOM   2377 C C   . PRO B 1 29  ? 20.61700 8.81600   188.02500 1.000 12.12000 ? 29  PRO B C   1 
ATOM   2378 O O   . PRO B 1 29  ? 21.03600 8.39900   189.11600 1.000 11.68000 ? 29  PRO B O   1 
ATOM   2379 C CB  . PRO B 1 29  ? 20.51200 11.27300  187.42000 1.000 13.27000 ? 29  PRO B CB  1 
ATOM   2380 C CG  . PRO B 1 29  ? 20.91700 12.02200  186.18900 1.000 18.75000 ? 29  PRO B CG  1 
ATOM   2381 C CD  . PRO B 1 29  ? 21.13700 10.97100  185.12500 1.000 15.09000 ? 29  PRO B CD  1 
ATOM   2382 N N   . ASP B 1 30  ? 19.55200 8.27300   187.42100 1.000 10.54000 ? 30  ASP B N   1 
ATOM   2383 C CA  . ASP B 1 30  ? 18.85800 7.18300   188.10000 1.000 13.19000 ? 30  ASP B CA  1 
ATOM   2384 C C   . ASP B 1 30  ? 19.69500 5.90700   188.10900 1.000 10.91000 ? 30  ASP B C   1 
ATOM   2385 O O   . ASP B 1 30  ? 19.65200 5.14600   189.08400 1.000 10.31000 ? 30  ASP B O   1 
ATOM   2386 C CB  . ASP B 1 30  ? 17.45400 6.95100   187.50500 1.000 13.16000 ? 30  ASP B CB  1 
ATOM   2387 C CG  . ASP B 1 30  ? 17.43600 6.68200   185.98300 1.000 15.49000 ? 30  ASP B CG  1 
ATOM   2388 O OD1 . ASP B 1 30  ? 18.47400 6.69800   185.28500 1.000 14.24000 ? 30  ASP B OD1 1 
ATOM   2389 O OD2 . ASP B 1 30  ? 16.31500 6.45200   185.48500 1.000 13.90000 ? 30  ASP B OD2 1 
ATOM   2390 N N   . MET B 1 31  ? 20.48800 5.68000   187.06000 1.000 9.67000  ? 31  MET B N   1 
ATOM   2391 C CA  . MET B 1 31  ? 21.42700 4.56100   187.05800 1.000 9.98000  ? 31  MET B CA  1 
ATOM   2392 C C   . MET B 1 31  ? 22.46500 4.71000   188.16500 1.000 10.72000 ? 31  MET B C   1 
ATOM   2393 O O   . MET B 1 31  ? 22.78300 3.74800   188.87700 1.000 8.44000  ? 31  MET B O   1 
ATOM   2394 C CB  . MET B 1 31  ? 22.11200 4.47600   185.69200 1.000 10.26000 ? 31  MET B CB  1 
ATOM   2395 C CG  . MET B 1 31  ? 23.03400 3.26400   185.50800 1.000 7.93000  ? 31  MET B CG  1 
ATOM   2396 S SD  . MET B 1 31  ? 22.08400 1.74400   185.27000 1.000 9.20000  ? 31  MET B SD  1 
ATOM   2397 C CE  . MET B 1 31  ? 22.40700 0.89100   186.82300 1.000 9.09000  ? 31  MET B CE  1 
ATOM   2398 N N   . LYS B 1 32  ? 23.02900 5.91400   188.29900 1.000 8.12000  ? 32  LYS B N   1 
ATOM   2399 C CA  . LYS B 1 32  ? 24.06200 6.14300   189.30200 1.000 11.66000 ? 32  LYS B CA  1 
ATOM   2400 C C   . LYS B 1 32  ? 23.51500 5.93500   190.70800 1.000 13.82000 ? 32  LYS B C   1 
ATOM   2401 O O   . LYS B 1 32  ? 24.18000 5.33000   191.55700 1.000 12.21000 ? 32  LYS B O   1 
ATOM   2402 C CB  . LYS B 1 32  ? 24.62900 7.55500   189.15300 1.000 13.07000 ? 32  LYS B CB  1 
ATOM   2403 C CG  . LYS B 1 32  ? 25.78500 7.83800   190.10000 1.000 15.88000 ? 32  LYS B CG  1 
ATOM   2404 C CD  . LYS B 1 32  ? 26.37600 9.21400   189.85800 1.000 23.32000 ? 32  LYS B CD  1 
ATOM   2405 C CE  . LYS B 1 32  ? 27.59900 9.42800   190.73700 1.000 25.41000 ? 32  LYS B CE  1 
ATOM   2406 N NZ  . LYS B 1 32  ? 28.09300 10.83000  190.66100 1.000 27.97000 ? 32  LYS B NZ  1 
ATOM   2407 N N   . ALA B 1 33  ? 22.29600 6.41500   190.96500 1.000 10.58000 ? 33  ALA B N   1 
ATOM   2408 C CA  . ALA B 1 33  ? 21.69500 6.25300   192.28700 1.000 14.08000 ? 33  ALA B CA  1 
ATOM   2409 C C   . ALA B 1 33  ? 21.48600 4.78200   192.62600 1.000 14.90000 ? 33  ALA B C   1 
ATOM   2410 O O   . ALA B 1 33  ? 21.69400 4.36600   193.77300 1.000 12.37000 ? 33  ALA B O   1 
ATOM   2411 C CB  . ALA B 1 33  ? 20.37000 7.01200   192.36200 1.000 12.46000 ? 33  ALA B CB  1 
ATOM   2412 N N   . PHE B 1 34  ? 21.08300 3.97600   191.64000 1.000 12.13000 ? 34  PHE B N   1 
ATOM   2413 C CA  . PHE B 1 34  ? 20.91700 2.54700   191.88100 1.000 13.81000 ? 34  PHE B CA  1 
ATOM   2414 C C   . PHE B 1 34  ? 22.24700 1.88000   192.20200 1.000 13.09000 ? 34  PHE B C   1 
ATOM   2415 O O   . PHE B 1 34  ? 22.32600 1.04600   193.11500 1.000 12.47000 ? 34  PHE B O   1 
ATOM   2416 C CB  . PHE B 1 34  ? 20.27100 1.87800   190.66700 1.000 10.36000 ? 34  PHE B CB  1 
ATOM   2417 C CG  . PHE B 1 34  ? 20.03100 0.40100   190.84400 1.000 10.25000 ? 34  PHE B CG  1 
ATOM   2418 C CD1 . PHE B 1 34  ? 19.04300 -0.05700  191.70800 1.000 14.82000 ? 34  PHE B CD1 1 
ATOM   2419 C CD2 . PHE B 1 34  ? 20.80100 -0.52500  190.16400 1.000 11.57000 ? 34  PHE B CD2 1 
ATOM   2420 C CE1 . PHE B 1 34  ? 18.82100 -1.41400  191.86800 1.000 15.86000 ? 34  PHE B CE1 1 
ATOM   2421 C CE2 . PHE B 1 34  ? 20.57900 -1.88600  190.31900 1.000 11.82000 ? 34  PHE B CE2 1 
ATOM   2422 C CZ  . PHE B 1 34  ? 19.58700 -2.32900  191.16600 1.000 9.76000  ? 34  PHE B CZ  1 
ATOM   2423 N N   . LEU B 1 35  ? 23.30200 2.21400   191.44900 1.000 9.63000  ? 35  LEU B N   1 
ATOM   2424 C CA  . LEU B 1 35  ? 24.61900 1.64900   191.73900 1.000 8.47000  ? 35  LEU B CA  1 
ATOM   2425 C C   . LEU B 1 35  ? 25.09500 2.04600   193.13000 1.000 11.17000 ? 35  LEU B C   1 
ATOM   2426 O O   . LEU B 1 35  ? 25.71100 1.23800   193.83800 1.000 12.25000 ? 35  LEU B O   1 
ATOM   2427 C CB  . LEU B 1 35  ? 25.64200 2.09700   190.69900 1.000 8.45000  ? 35  LEU B CB  1 
ATOM   2428 C CG  . LEU B 1 35  ? 25.44300 1.56400   189.28300 1.000 10.23000 ? 35  LEU B CG  1 
ATOM   2429 C CD1 . LEU B 1 35  ? 26.54700 2.09800   188.38300 1.000 11.28000 ? 35  LEU B CD1 1 
ATOM   2430 C CD2 . LEU B 1 35  ? 25.41900 0.02800   189.28100 1.000 12.63000 ? 35  LEU B CD2 1 
ATOM   2431 N N   . GLU B 1 36  ? 24.83400 3.29000   193.53200 1.000 10.06000 ? 36  GLU B N   1 
ATOM   2432 C CA  . GLU B 1 36  ? 25.25100 3.71600   194.86500 1.000 11.54000 ? 36  GLU B CA  1 
ATOM   2433 C C   . GLU B 1 36  ? 24.49700 2.94500   195.93700 1.000 15.60000 ? 36  GLU B C   1 
ATOM   2434 O O   . GLU B 1 36  ? 25.07600 2.55000   196.95300 1.000 13.69000 ? 36  GLU B O   1 
ATOM   2435 C CB  . GLU B 1 36  ? 25.04800 5.21900   195.02200 1.000 14.48000 ? 36  GLU B CB  1 
ATOM   2436 C CG  . GLU B 1 36  ? 26.08200 6.02600   194.24800 1.000 18.49000 ? 36  GLU B CG  1 
ATOM   2437 C CD  . GLU B 1 36  ? 25.73100 7.50100   194.14900 1.000 28.46000 ? 36  GLU B CD  1 
ATOM   2438 O OE1 . GLU B 1 36  ? 26.60000 8.29200   193.71500 1.000 32.07000 ? 36  GLU B OE1 1 
ATOM   2439 O OE2 . GLU B 1 36  ? 24.58900 7.86900   194.50100 1.000 32.52000 ? 36  GLU B OE2 1 
ATOM   2440 N N   . MET B 1 37  ? 23.21100 2.69100   195.71200 1.000 13.07000 ? 37  MET B N   1 
ATOM   2441 C CA  . MET B 1 37  ? 22.45600 1.88600   196.66200 1.000 14.75000 ? 37  MET B CA  1 
ATOM   2442 C C   . MET B 1 37  ? 22.99800 0.46100   196.73600 1.000 16.51000 ? 37  MET B C   1 
ATOM   2443 O O   . MET B 1 37  ? 23.14600 -0.10400  197.82900 1.000 14.52000 ? 37  MET B O   1 
ATOM   2444 C CB  . MET B 1 37  ? 20.98200 1.89300   196.27500 1.000 17.40000 ? 37  MET B CB  1 
ATOM   2445 C CG  . MET B 1 37  ? 20.11500 1.20100   197.26800 1.000 28.17000 ? 37  MET B CG  1 
ATOM   2446 S SD  . MET B 1 37  ? 19.56900 -0.39800  196.69100 1.000 47.87000 ? 37  MET B SD  1 
ATOM   2447 C CE  . MET B 1 37  ? 18.15500 0.09500   195.71100 1.000 28.34000 ? 37  MET B CE  1 
ATOM   2448 N N   . MET B 1 38  ? 23.32300 -0.13400  195.58400 1.000 13.75000 ? 38  MET B N   1 
ATOM   2449 C CA  . MET B 1 38  ? 23.84400 -1.49500  195.58800 1.000 17.10000 ? 38  MET B CA  1 
ATOM   2450 C C   . MET B 1 38  ? 25.21500 -1.56800  196.24600 1.000 14.53000 ? 38  MET B C   1 
ATOM   2451 O O   . MET B 1 38  ? 25.57400 -2.60700  196.81400 1.000 15.20000 ? 38  MET B O   1 
ATOM   2452 C CB  . MET B 1 38  ? 23.91400 -2.04000  194.15800 1.000 17.61000 ? 38  MET B CB  1 
ATOM   2453 C CG  . MET B 1 38  ? 22.55800 -2.27900  193.53200 1.000 19.64000 ? 38  MET B CG  1 
ATOM   2454 S SD  . MET B 1 38  ? 21.79900 -3.78800  194.16000 1.000 29.91000 ? 38  MET B SD  1 
ATOM   2455 C CE  . MET B 1 38  ? 20.43000 -3.14800  195.06400 1.000 23.06000 ? 38  MET B CE  1 
ATOM   2456 N N   . ALA B 1 39  ? 25.99700 -0.49000  196.17100 1.000 10.82000 ? 39  ALA B N   1 
ATOM   2457 C CA  . ALA B 1 39  ? 27.29500 -0.46800  196.83300 1.000 16.98000 ? 39  ALA B CA  1 
ATOM   2458 C C   . ALA B 1 39  ? 27.16100 -0.45300  198.34600 1.000 13.53000 ? 39  ALA B C   1 
ATOM   2459 O O   . ALA B 1 39  ? 28.09000 -0.87200  199.04100 1.000 18.19000 ? 39  ALA B O   1 
ATOM   2460 C CB  . ALA B 1 39  ? 28.10400 0.74600   196.38300 1.000 16.25000 ? 39  ALA B CB  1 
ATOM   2461 N N   . GLN B 1 40  ? 26.02600 0.01000   198.86600 1.000 13.44000 ? 40  GLN B N   1 
ATOM   2462 C CA  . GLN B 1 40  ? 25.81900 0.01800   200.30700 1.000 17.23000 ? 40  GLN B CA  1 
ATOM   2463 C C   . GLN B 1 40  ? 25.52200 -1.37100  200.86300 1.000 18.98000 ? 40  GLN B C   1 
ATOM   2464 O O   . GLN B 1 40  ? 25.68600 -1.58400  202.06800 1.000 14.97000 ? 40  GLN B O   1 
ATOM   2465 C CB  . GLN B 1 40  ? 24.68400 0.97400   200.66500 1.000 19.07000 ? 40  GLN B CB  1 
ATOM   2466 C CG  . GLN B 1 40  ? 25.00400 2.42000   200.40300 1.000 21.31000 ? 40  GLN B CG  1 
ATOM   2467 C CD  . GLN B 1 40  ? 23.86900 3.33800   200.81400 1.000 36.92000 ? 40  GLN B CD  1 
ATOM   2468 O OE1 . GLN B 1 40  ? 23.22700 3.13200   201.85300 1.000 41.40000 ? 40  GLN B OE1 1 
ATOM   2469 N NE2 . GLN B 1 40  ? 23.61200 4.35900   200.00100 1.000 38.26000 ? 40  GLN B NE2 1 
ATOM   2470 N N   . VAL B 1 41  ? 25.09300 -2.31700  200.02500 1.000 16.64000 ? 41  VAL B N   1 
ATOM   2471 C CA  . VAL B 1 41  ? 24.84400 -3.67400  200.50000 1.000 18.35000 ? 41  VAL B CA  1 
ATOM   2472 C C   . VAL B 1 41  ? 26.15800 -4.32500  200.90200 1.000 17.32000 ? 41  VAL B C   1 
ATOM   2473 O O   . VAL B 1 41  ? 27.17400 -4.20900  200.20400 1.000 20.96000 ? 41  VAL B O   1 
ATOM   2474 C CB  . VAL B 1 41  ? 24.11900 -4.50300  199.42500 1.000 23.01000 ? 41  VAL B CB  1 
ATOM   2475 C CG1 . VAL B 1 41  ? 23.94200 -5.94100  199.89300 1.000 22.41000 ? 41  VAL B CG1 1 
ATOM   2476 C CG2 . VAL B 1 41  ? 22.78500 -3.88000  199.11500 1.000 16.92000 ? 41  VAL B CG2 1 
ATOM   2477 N N   . ASN B 1 42  ? 26.15000 -5.00500  202.04300 1.000 21.46000 ? 42  ASN B N   1 
ATOM   2478 C CA  . ASN B 1 42  ? 27.34200 -5.66500  202.57800 1.000 26.73000 ? 42  ASN B CA  1 
ATOM   2479 C C   . ASN B 1 42  ? 27.01500 -7.14700  202.75500 1.000 31.58000 ? 42  ASN B C   1 
ATOM   2480 O O   . ASN B 1 42  ? 26.49400 -7.56600  203.79300 1.000 27.37000 ? 42  ASN B O   1 
ATOM   2481 C CB  . ASN B 1 42  ? 27.77600 -5.00800  203.88600 1.000 24.68000 ? 42  ASN B CB  1 
ATOM   2482 C CG  . ASN B 1 42  ? 29.13600 -5.47800  204.36100 1.000 31.80000 ? 42  ASN B CG  1 
ATOM   2483 O OD1 . ASN B 1 42  ? 29.79200 -6.29000  203.71100 1.000 32.75000 ? 42  ASN B OD1 1 
ATOM   2484 N ND2 . ASN B 1 42  ? 29.56900 -4.96400  205.51100 1.000 33.22000 ? 42  ASN B ND2 1 
ATOM   2485 N N   . GLY B 1 43  ? 27.30800 -7.93900  201.72600 1.000 29.65000 ? 43  GLY B N   1 
ATOM   2486 C CA  . GLY B 1 43  ? 27.02400 -9.35400  201.75000 1.000 27.19000 ? 43  GLY B CA  1 
ATOM   2487 C C   . GLY B 1 43  ? 28.00400 -10.14200 200.90700 1.000 32.44000 ? 43  GLY B C   1 
ATOM   2488 O O   . GLY B 1 43  ? 29.01000 -9.61200  200.42400 1.000 29.05000 ? 43  GLY B O   1 
ATOM   2489 N N   . PRO B 1 44  ? 27.73400 -11.43200 200.72000 1.000 35.30000 ? 44  PRO B N   1 
ATOM   2490 C CA  . PRO B 1 44  ? 28.64200 -12.26300 199.92100 1.000 24.15000 ? 44  PRO B CA  1 
ATOM   2491 C C   . PRO B 1 44  ? 28.53800 -11.95500 198.43400 1.000 23.20000 ? 44  PRO B C   1 
ATOM   2492 O O   . PRO B 1 44  ? 27.50000 -11.51000 197.93800 1.000 22.00000 ? 44  PRO B O   1 
ATOM   2493 C CB  . PRO B 1 44  ? 28.17400 -13.69600 200.21900 1.000 25.91000 ? 44  PRO B CB  1 
ATOM   2494 C CG  . PRO B 1 44  ? 27.30800 -13.59100 201.44300 1.000 33.16000 ? 44  PRO B CG  1 
ATOM   2495 C CD  . PRO B 1 44  ? 26.69000 -12.22900 201.38500 1.000 32.69000 ? 44  PRO B CD  1 
ATOM   2496 N N   . LYS B 1 45  ? 29.64400 -12.19100 197.72200 1.000 18.46000 ? 45  LYS B N   1 
ATOM   2497 C CA  . LYS B 1 45  ? 29.60500 -12.27400 196.26900 1.000 20.62000 ? 45  LYS B CA  1 
ATOM   2498 C C   . LYS B 1 45  ? 29.01700 -13.62400 195.84900 1.000 13.40000 ? 45  LYS B C   1 
ATOM   2499 O O   . LYS B 1 45  ? 28.89800 -14.54800 196.65100 1.000 11.81000 ? 45  LYS B O   1 
ATOM   2500 C CB  . LYS B 1 45  ? 31.00500 -12.08300 195.68300 1.000 18.51000 ? 45  LYS B CB  1 
ATOM   2501 C CG  . LYS B 1 45  ? 31.67100 -10.76900 196.08400 1.000 25.51000 ? 45  LYS B CG  1 
ATOM   2502 C CD  . LYS B 1 45  ? 33.13800 -10.72600 195.67800 1.000 28.79000 ? 45  LYS B CD  1 
ATOM   2503 C CE  . LYS B 1 45  ? 33.85700 -9.56000  196.36000 1.000 33.77000 ? 45  LYS B CE  1 
ATOM   2504 N NZ  . LYS B 1 45  ? 34.77900 -8.83800  195.44200 1.000 38.76000 ? 45  LYS B NZ  1 
ATOM   2505 N N   . LEU B 1 46  ? 28.64700 -13.73600 194.56600 1.000 15.48000 ? 46  LEU B N   1 
ATOM   2506 C CA  . LEU B 1 46  ? 27.96500 -14.94200 194.09700 1.000 14.20000 ? 46  LEU B CA  1 
ATOM   2507 C C   . LEU B 1 46  ? 28.79500 -16.19800 194.33800 1.000 12.78000 ? 46  LEU B C   1 
ATOM   2508 O O   . LEU B 1 46  ? 28.25300 -17.23900 194.73200 1.000 12.78000 ? 46  LEU B O   1 
ATOM   2509 C CB  . LEU B 1 46  ? 27.62600 -14.81500 192.60700 1.000 17.97000 ? 46  LEU B CB  1 
ATOM   2510 C CG  . LEU B 1 46  ? 26.48300 -13.86000 192.24400 1.000 19.96000 ? 46  LEU B CG  1 
ATOM   2511 C CD1 . LEU B 1 46  ? 26.37700 -13.69400 190.72300 1.000 18.65000 ? 46  LEU B CD1 1 
ATOM   2512 C CD2 . LEU B 1 46  ? 25.16300 -14.33300 192.83000 1.000 20.26000 ? 46  LEU B CD2 1 
ATOM   2513 N N   . SER B 1 47  ? 30.10900 -16.12300 194.10200 1.000 13.96000 ? 47  SER B N   1 
ATOM   2514 C CA  . SER B 1 47  ? 30.98100 -17.28400 194.26900 1.000 17.31000 ? 47  SER B CA  1 
ATOM   2515 C C   . SER B 1 47  ? 31.06400 -17.77000 195.70900 1.000 17.10000 ? 47  SER B C   1 
ATOM   2516 O O   . SER B 1 47  ? 31.35900 -18.95200 195.93200 1.000 14.43000 ? 47  SER B O   1 
ATOM   2517 C CB  . SER B 1 47  ? 32.38800 -16.96200 193.78100 1.000 16.26000 ? 47  SER B CB  1 
ATOM   2518 O OG  . SER B 1 47  ? 32.98700 -15.98600 194.61600 1.000 20.39000 ? 47  SER B OG  1 
ATOM   2519 N N   . GLU B 1 48  ? 30.82400 -16.89200 196.68700 1.000 14.08000 ? 48  GLU B N   1 
ATOM   2520 C CA  . GLU B 1 48  ? 30.91100 -17.27600 198.08800 1.000 12.55000 ? 48  GLU B CA  1 
ATOM   2521 C C   . GLU B 1 48  ? 29.65400 -17.94600 198.60400 1.000 16.21000 ? 48  GLU B C   1 
ATOM   2522 O O   . GLU B 1 48  ? 29.66200 -18.45000 199.73300 1.000 17.53000 ? 48  GLU B O   1 
ATOM   2523 C CB  . GLU B 1 48  ? 31.17100 -16.05600 198.96800 1.000 15.92000 ? 48  GLU B CB  1 
ATOM   2524 C CG  . GLU B 1 48  ? 32.23800 -15.10900 198.49600 1.000 19.62000 ? 48  GLU B CG  1 
ATOM   2525 C CD  . GLU B 1 48  ? 32.28800 -13.90000 199.41300 1.000 25.83000 ? 48  GLU B CD  1 
ATOM   2526 O OE1 . GLU B 1 48  ? 32.23100 -12.75200 198.93000 1.000 29.26000 ? 48  GLU B OE1 1 
ATOM   2527 O OE2 . GLU B 1 48  ? 32.33200 -14.11400 200.64400 1.000 37.44000 ? 48  GLU B OE2 1 
ATOM   2528 N N   . MET B 1 49  ? 28.57300 -17.93200 197.83200 1.000 13.14000 ? 49  MET B N   1 
ATOM   2529 C CA  . MET B 1 49  ? 27.31900 -18.52800 198.26000 1.000 14.26000 ? 49  MET B CA  1 
ATOM   2530 C C   . MET B 1 49  ? 27.21700 -19.96900 197.77200 1.000 12.19000 ? 49  MET B C   1 
ATOM   2531 O O   . MET B 1 49  ? 27.91200 -20.38800 196.84200 1.000 13.99000 ? 49  MET B O   1 
ATOM   2532 C CB  . MET B 1 49  ? 26.12900 -17.73500 197.71200 1.000 12.81000 ? 49  MET B CB  1 
ATOM   2533 C CG  . MET B 1 49  ? 26.18400 -16.23800 197.92100 1.000 16.81000 ? 49  MET B CG  1 
ATOM   2534 S SD  . MET B 1 49  ? 24.81200 -15.46300 197.03000 1.000 16.95000 ? 49  MET B SD  1 
ATOM   2535 C CE  . MET B 1 49  ? 25.14000 -13.73000 197.37600 1.000 24.07000 ? 49  MET B CE  1 
ATOM   2536 N N   . SER B 1 50  ? 26.31800 -20.72100 198.39900 1.000 13.88000 ? 50  SER B N   1 
ATOM   2537 C CA  . SER B 1 50  ? 25.88000 -21.96200 197.78500 1.000 14.43000 ? 50  SER B CA  1 
ATOM   2538 C C   . SER B 1 50  ? 25.23100 -21.64600 196.43900 1.000 11.85000 ? 50  SER B C   1 
ATOM   2539 O O   . SER B 1 50  ? 24.79000 -20.51900 196.18600 1.000 9.74000  ? 50  SER B O   1 
ATOM   2540 C CB  . SER B 1 50  ? 24.89700 -22.70400 198.69000 1.000 15.60000 ? 50  SER B CB  1 
ATOM   2541 O OG  . SER B 1 50  ? 23.59200 -22.13500 198.64300 1.000 13.37000 ? 50  SER B OG  1 
ATOM   2542 N N   . LEU B 1 51  ? 25.18600 -22.65300 195.56700 1.000 8.91000  ? 51  LEU B N   1 
ATOM   2543 C CA  . LEU B 1 51  ? 24.50800 -22.46800 194.28500 1.000 8.78000  ? 51  LEU B CA  1 
ATOM   2544 C C   . LEU B 1 51  ? 23.04600 -22.08200 194.48600 1.000 10.34000 ? 51  LEU B C   1 
ATOM   2545 O O   . LEU B 1 51  ? 22.53100 -21.18700 193.80200 1.000 8.77000  ? 51  LEU B O   1 
ATOM   2546 C CB  . LEU B 1 51  ? 24.62200 -23.73700 193.43800 1.000 8.74000  ? 51  LEU B CB  1 
ATOM   2547 C CG  . LEU B 1 51  ? 26.02100 -23.98300 192.86700 1.000 10.23000 ? 51  LEU B CG  1 
ATOM   2548 C CD1 . LEU B 1 51  ? 26.10300 -25.33400 192.16600 1.000 13.92000 ? 51  LEU B CD1 1 
ATOM   2549 C CD2 . LEU B 1 51  ? 26.43800 -22.86300 191.91800 1.000 13.97000 ? 51  LEU B CD2 1 
ATOM   2550 N N   . ASP B 1 52  ? 22.35700 -22.74500 195.42200 1.000 10.27000 ? 52  ASP B N   1 
ATOM   2551 C CA  . ASP B 1 52  ? 20.96700 -22.38300 195.69000 1.000 13.54000 ? 52  ASP B CA  1 
ATOM   2552 C C   . ASP B 1 52  ? 20.85800 -20.93000 196.14000 1.000 10.29000 ? 52  ASP B C   1 
ATOM   2553 O O   . ASP B 1 52  ? 19.95400 -20.20300 195.70500 1.000 9.23000  ? 52  ASP B O   1 
ATOM   2554 C CB  . ASP B 1 52  ? 20.37100 -23.30800 196.75300 1.000 13.62000 ? 52  ASP B CB  1 
ATOM   2555 C CG  . ASP B 1 52  ? 19.99900 -24.68400 196.21500 1.000 23.37000 ? 52  ASP B CG  1 
ATOM   2556 O OD1 . ASP B 1 52  ? 20.08600 -24.92400 194.98900 1.000 24.31000 ? 52  ASP B OD1 1 
ATOM   2557 O OD2 . ASP B 1 52  ? 19.60800 -25.53800 197.04200 1.000 30.51000 ? 52  ASP B OD2 1 
ATOM   2558 N N   . GLU B 1 53  ? 21.76000 -20.49500 197.02200 1.000 7.86000  ? 53  GLU B N   1 
ATOM   2559 C CA  . GLU B 1 53  ? 21.71100 -19.12500 197.52700 1.000 11.09000 ? 53  GLU B CA  1 
ATOM   2560 C C   . GLU B 1 53  ? 21.99500 -18.11500 196.42400 1.000 9.64000  ? 53  GLU B C   1 
ATOM   2561 O O   . GLU B 1 53  ? 21.34300 -17.06600 196.35300 1.000 10.03000 ? 53  GLU B O   1 
ATOM   2562 C CB  . GLU B 1 53  ? 22.70600 -18.95100 198.67000 1.000 12.97000 ? 53  GLU B CB  1 
ATOM   2563 C CG  . GLU B 1 53  ? 22.21700 -19.55400 199.99200 1.000 14.33000 ? 53  GLU B CG  1 
ATOM   2564 C CD  . GLU B 1 53  ? 23.33600 -19.74600 201.00100 1.000 25.40000 ? 53  GLU B CD  1 
ATOM   2565 O OE1 . GLU B 1 53  ? 24.51300 -19.47500 200.66000 1.000 20.33000 ? 53  GLU B OE1 1 
ATOM   2566 O OE2 . GLU B 1 53  ? 23.03000 -20.16400 202.13900 1.000 25.15000 ? 53  GLU B OE2 1 
ATOM   2567 N N   . ALA B 1 54  ? 22.98200 -18.40000 195.57200 1.000 8.19000  ? 54  ALA B N   1 
ATOM   2568 C CA  . ALA B 1 54  ? 23.27800 -17.50800 194.45500 1.000 9.44000  ? 54  ALA B CA  1 
ATOM   2569 C C   . ALA B 1 54  ? 22.08000 -17.37400 193.52800 1.000 9.00000  ? 54  ALA B C   1 
ATOM   2570 O O   . ALA B 1 54  ? 21.76000 -16.27000 193.06300 1.000 8.13000  ? 54  ALA B O   1 
ATOM   2571 C CB  . ALA B 1 54  ? 24.49300 -18.02300 193.68000 1.000 9.28000  ? 54  ALA B CB  1 
ATOM   2572 N N   . ARG B 1 55  ? 21.40600 -18.49100 193.24800 1.000 7.71000  ? 55  ARG B N   1 
ATOM   2573 C CA  . ARG B 1 55  ? 20.25000 -18.45700 192.36200 1.000 8.22000  ? 55  ARG B CA  1 
ATOM   2574 C C   . ARG B 1 55  ? 19.08800 -17.69800 193.00000 1.000 10.32000 ? 55  ARG B C   1 
ATOM   2575 O O   . ARG B 1 55  ? 18.38700 -16.93700 192.31800 1.000 7.59000  ? 55  ARG B O   1 
ATOM   2576 C CB  . ARG B 1 55  ? 19.86000 -19.88600 191.97400 1.000 7.39000  ? 55  ARG B CB  1 
ATOM   2577 C CG  . ARG B 1 55  ? 20.89400 -20.48800 190.99600 1.000 6.26000  ? 55  ARG B CG  1 
ATOM   2578 C CD  . ARG B 1 55  ? 20.82400 -22.00500 190.80500 1.000 7.55000  ? 55  ARG B CD  1 
ATOM   2579 N NE  . ARG B 1 55  ? 21.82600 -22.40800 189.81800 1.000 7.15000  ? 55  ARG B NE  1 
ATOM   2580 C CZ  . ARG B 1 55  ? 22.36600 -23.61600 189.73400 1.000 9.19000  ? 55  ARG B CZ  1 
ATOM   2581 N NH1 . ARG B 1 55  ? 23.28100 -23.86400 188.80400 1.000 7.42000  ? 55  ARG B NH1 1 
ATOM   2582 N NH2 . ARG B 1 55  ? 21.98600 -24.57400 190.57600 1.000 9.05000  ? 55  ARG B NH2 1 
ATOM   2583 N N   . ALA B 1 56  ? 18.88300 -17.87200 194.30800 1.000 9.03000  ? 56  ALA B N   1 
ATOM   2584 C CA  . ALA B 1 56  ? 17.82900 -17.12200 194.99100 1.000 8.77000  ? 56  ALA B CA  1 
ATOM   2585 C C   . ALA B 1 56  ? 18.15600 -15.63300 195.06200 1.000 8.91000  ? 56  ALA B C   1 
ATOM   2586 O O   . ALA B 1 56  ? 17.25100 -14.78800 194.97500 1.000 10.24000 ? 56  ALA B O   1 
ATOM   2587 C CB  . ALA B 1 56  ? 17.60400 -17.68000 196.39900 1.000 8.49000  ? 56  ALA B CB  1 
ATOM   2588 N N   . SER B 1 57  ? 19.43500 -15.28800 195.25900 1.000 8.45000  ? 57  SER B N   1 
ATOM   2589 C CA  . SER B 1 57  ? 19.80800 -13.88000 195.33900 1.000 9.76000  ? 57  SER B CA  1 
ATOM   2590 C C   . SER B 1 57  ? 19.57200 -13.16300 194.02000 1.000 9.29000  ? 57  SER B C   1 
ATOM   2591 O O   . SER B 1 57  ? 19.23100 -11.97600 194.01500 1.000 8.58000  ? 57  SER B O   1 
ATOM   2592 C CB  . SER B 1 57  ? 21.27300 -13.73000 195.75100 1.000 12.32000 ? 57  SER B CB  1 
ATOM   2593 O OG  . SER B 1 57  ? 21.48700 -14.30700 197.02300 1.000 32.55000 ? 57  SER B OG  1 
ATOM   2594 N N   . TYR B 1 58  ? 19.78300 -13.85600 192.89900 1.000 7.96000  ? 58  TYR B N   1 
ATOM   2595 C CA  . TYR B 1 58  ? 19.52800 -13.25700 191.59100 1.000 7.35000  ? 58  TYR B CA  1 
ATOM   2596 C C   . TYR B 1 58  ? 18.04500 -12.97700 191.40500 1.000 8.14000  ? 58  TYR B C   1 
ATOM   2597 O O   . TYR B 1 58  ? 17.66200 -11.90500 190.91700 1.000 8.72000  ? 58  TYR B O   1 
ATOM   2598 C CB  . TYR B 1 58  ? 20.05500 -14.19900 190.50500 1.000 7.51000  ? 58  TYR B CB  1 
ATOM   2599 C CG  . TYR B 1 58  ? 20.11200 -13.66200 189.09000 1.000 8.64000  ? 58  TYR B CG  1 
ATOM   2600 C CD1 . TYR B 1 58  ? 20.56400 -12.37300 188.81800 1.000 9.53000  ? 58  TYR B CD1 1 
ATOM   2601 C CD2 . TYR B 1 58  ? 19.75100 -14.47200 188.02000 1.000 8.32000  ? 58  TYR B CD2 1 
ATOM   2602 C CE1 . TYR B 1 58  ? 20.63400 -11.90700 187.50500 1.000 12.30000 ? 58  TYR B CE1 1 
ATOM   2603 C CE2 . TYR B 1 58  ? 19.82200 -14.02400 186.71600 1.000 8.59000  ? 58  TYR B CE2 1 
ATOM   2604 C CZ  . TYR B 1 58  ? 20.26100 -12.73900 186.46300 1.000 11.44000 ? 58  TYR B CZ  1 
ATOM   2605 O OH  . TYR B 1 58  ? 20.32200 -12.30400 185.15700 1.000 10.73000 ? 58  TYR B OH  1 
ATOM   2606 N N   . LEU B 1 59  ? 17.19300 -13.93200 191.79700 1.000 9.19000  ? 59  LEU B N   1 
ATOM   2607 C CA  . LEU B 1 59  ? 15.75700 -13.69100 191.77600 1.000 8.86000  ? 59  LEU B CA  1 
ATOM   2608 C C   . LEU B 1 59  ? 15.39700 -12.47700 192.61800 1.000 7.95000  ? 59  LEU B C   1 
ATOM   2609 O O   . LEU B 1 59  ? 14.60800 -11.62600 192.19300 1.000 7.64000  ? 59  LEU B O   1 
ATOM   2610 C CB  . LEU B 1 59  ? 15.00300 -14.92500 192.27200 1.000 7.18000  ? 59  LEU B CB  1 
ATOM   2611 C CG  . LEU B 1 59  ? 13.48800 -14.72600 192.38500 1.000 11.46000 ? 59  LEU B CG  1 
ATOM   2612 C CD1 . LEU B 1 59  ? 12.88800 -14.47400 190.99700 1.000 9.05000  ? 59  LEU B CD1 1 
ATOM   2613 C CD2 . LEU B 1 59  ? 12.83400 -15.93400 193.01700 1.000 14.65000 ? 59  LEU B CD2 1 
ATOM   2614 N N   . ALA B 1 60  ? 15.98100 -12.37100 193.81200 1.000 9.09000  ? 60  ALA B N   1 
ATOM   2615 C CA  . ALA B 1 60  ? 15.67800 -11.24300 194.68500 1.000 10.13000 ? 60  ALA B CA  1 
ATOM   2616 C C   . ALA B 1 60  ? 16.10400 -9.91800  194.06300 1.000 9.89000  ? 60  ALA B C   1 
ATOM   2617 O O   . ALA B 1 60  ? 15.40400 -8.90700  194.20800 1.000 10.31000 ? 60  ALA B O   1 
ATOM   2618 C CB  . ALA B 1 60  ? 16.35100 -11.44600 196.04600 1.000 10.18000 ? 60  ALA B CB  1 
ATOM   2619 N N   . MET B 1 61  ? 17.25400 -9.89500  193.38300 1.000 7.60000  ? 61  MET B N   1 
ATOM   2620 C CA  . MET B 1 61  ? 17.70900 -8.67400  192.72400 1.000 10.31000 ? 61  MET B CA  1 
ATOM   2621 C C   . MET B 1 61  ? 16.71800 -8.21600  191.66200 1.000 8.24000  ? 61  MET B C   1 
ATOM   2622 O O   . MET B 1 61  ? 16.39500 -7.02500  191.57400 1.000 8.57000  ? 61  MET B O   1 
ATOM   2623 C CB  . MET B 1 61  ? 19.09200 -8.87500  192.09500 1.000 11.78000 ? 61  MET B CB  1 
ATOM   2624 C CG  . MET B 1 61  ? 19.70900 -7.56600  191.57500 1.000 22.67000 ? 61  MET B CG  1 
ATOM   2625 S SD  . MET B 1 61  ? 21.22700 -7.77100  190.60500 1.000 48.38000 ? 61  MET B SD  1 
ATOM   2626 C CE  . MET B 1 61  ? 20.60600 -7.71100  188.92000 1.000 29.76000 ? 61  MET B CE  1 
ATOM   2627 N N   . HIS B 1 62  ? 16.24300 -9.14400  190.82400 1.000 9.89000  ? 62  HIS B N   1 
ATOM   2628 C CA  . HIS B 1 62  ? 15.29900 -8.75500  189.77900 1.000 9.80000  ? 62  HIS B CA  1 
ATOM   2629 C C   . HIS B 1 62  ? 13.93500 -8.41200  190.36500 1.000 11.79000 ? 62  HIS B C   1 
ATOM   2630 O O   . HIS B 1 62  ? 13.26600 -7.48700  189.88900 1.000 10.68000 ? 62  HIS B O   1 
ATOM   2631 C CB  . HIS B 1 62  ? 15.18200 -9.86200  188.73200 1.000 10.23000 ? 62  HIS B CB  1 
ATOM   2632 C CG  . HIS B 1 62  ? 16.32200 -9.88600  187.76500 1.000 12.94000 ? 62  HIS B CG  1 
ATOM   2633 N ND1 . HIS B 1 62  ? 16.34900 -10.71400 186.66400 1.000 9.83000  ? 62  HIS B ND1 1 
ATOM   2634 C CD2 . HIS B 1 62  ? 17.47200 -9.17000  187.72700 1.000 13.91000 ? 62  HIS B CD2 1 
ATOM   2635 C CE1 . HIS B 1 62  ? 17.47300 -10.51800 185.99500 1.000 11.77000 ? 62  HIS B CE1 1 
ATOM   2636 N NE2 . HIS B 1 62  ? 18.17000 -9.58200  186.61500 1.000 10.74000 ? 62  HIS B NE2 1 
ATOM   2637 N N   . ASN B 1 63  ? 13.50300 -9.13300  191.40200 1.000 11.83000 ? 63  ASN B N   1 
ATOM   2638 C CA  . ASN B 1 63  ? 12.25300 -8.76000  192.06800 1.000 14.33000 ? 63  ASN B CA  1 
ATOM   2639 C C   . ASN B 1 63  ? 12.32900 -7.34800  192.63900 1.000 15.03000 ? 63  ASN B C   1 
ATOM   2640 O O   . ASN B 1 63  ? 11.34600 -6.59900  192.59900 1.000 18.01000 ? 63  ASN B O   1 
ATOM   2641 C CB  . ASN B 1 63  ? 11.90900 -9.76100  193.17400 1.000 13.35000 ? 63  ASN B CB  1 
ATOM   2642 C CG  . ASN B 1 63  ? 11.31400 -11.04900 192.63200 1.000 17.48000 ? 63  ASN B CG  1 
ATOM   2643 O OD1 . ASN B 1 63  ? 10.88500 -11.11400 191.47800 1.000 17.85000 ? 63  ASN B OD1 1 
ATOM   2644 N ND2 . ASN B 1 63  ? 11.28600 -12.08700 193.46500 1.000 12.50000 ? 63  ASN B ND2 1 
ATOM   2645 N N   . LEU B 1 64  ? 13.48400 -6.96600  193.17300 1.000 9.01000  ? 64  LEU B N   1 
ATOM   2646 C CA  . LEU B 1 64  ? 13.63600 -5.62700  193.73200 1.000 11.49000 ? 64  LEU B CA  1 
ATOM   2647 C C   . LEU B 1 64  ? 13.68300 -4.57500  192.63100 1.000 15.32000 ? 64  LEU B C   1 
ATOM   2648 O O   . LEU B 1 64  ? 12.97700 -3.56200  192.69100 1.000 10.95000 ? 64  LEU B O   1 
ATOM   2649 C CB  . LEU B 1 64  ? 14.90400 -5.56500  194.58100 1.000 11.30000 ? 64  LEU B CB  1 
ATOM   2650 C CG  . LEU B 1 64  ? 15.25100 -4.24700  195.26900 1.000 20.13000 ? 64  LEU B CG  1 
ATOM   2651 C CD1 . LEU B 1 64  ? 14.56800 -4.17700  196.62500 1.000 28.65000 ? 64  LEU B CD1 1 
ATOM   2652 C CD2 . LEU B 1 64  ? 16.76400 -4.09200  195.40600 1.000 28.45000 ? 64  LEU B CD2 1 
ATOM   2653 N N   . ALA B 1 65  ? 14.50400 -4.80900  191.60900 1.000 9.65000  ? 65  ALA B N   1 
ATOM   2654 C CA  . ALA B 1 65  ? 14.85000 -3.76900  190.65000 1.000 10.15000 ? 65  ALA B CA  1 
ATOM   2655 C C   . ALA B 1 65  ? 13.86200 -3.62800  189.50100 1.000 9.87000  ? 65  ALA B C   1 
ATOM   2656 O O   . ALA B 1 65  ? 13.74800 -2.53500  188.93900 1.000 8.41000  ? 65  ALA B O   1 
ATOM   2657 C CB  . ALA B 1 65  ? 16.24000 -4.03900  190.07200 1.000 7.93000  ? 65  ALA B CB  1 
ATOM   2658 N N   . ASP B 1 66  ? 13.16200 -4.69000  189.12400 1.000 9.18000  ? 66  ASP B N   1 
ATOM   2659 C CA  . ASP B 1 66  ? 12.36300 -4.64800  187.90600 1.000 9.76000  ? 66  ASP B CA  1 
ATOM   2660 C C   . ASP B 1 66  ? 10.91700 -4.25900  188.20000 1.000 9.83000  ? 66  ASP B C   1 
ATOM   2661 O O   . ASP B 1 66  ? 10.44800 -4.32800  189.33300 1.000 10.12000 ? 66  ASP B O   1 
ATOM   2662 C CB  . ASP B 1 66  ? 12.39800 -5.99700  187.17900 1.000 9.90000  ? 66  ASP B CB  1 
ATOM   2663 C CG  . ASP B 1 66  ? 12.22400 -5.84300  185.66700 1.000 11.91000 ? 66  ASP B CG  1 
ATOM   2664 O OD1 . ASP B 1 66  ? 12.22700 -4.68100  185.19200 1.000 9.68000  ? 66  ASP B OD1 1 
ATOM   2665 O OD2 . ASP B 1 66  ? 12.08100 -6.86500  184.96100 1.000 10.59000 ? 66  ASP B OD2 1 
ATOM   2666 N N   . ARG B 1 67  ? 10.20900 -3.84700  187.14500 1.000 9.66000  ? 67  ARG B N   1 
ATOM   2667 C CA  . ARG B 1 67  ? 8.79000  -3.55500  187.25200 1.000 9.73000  ? 67  ARG B CA  1 
ATOM   2668 C C   . ARG B 1 67  ? 7.99100  -4.82900  187.53200 1.000 11.83000 ? 67  ARG B C   1 
ATOM   2669 O O   . ARG B 1 67  ? 8.45700  -5.94300  187.26200 1.000 8.88000  ? 67  ARG B O   1 
ATOM   2670 C CB  . ARG B 1 67  ? 8.28600  -2.91100  185.96500 1.000 9.04000  ? 67  ARG B CB  1 
ATOM   2671 C CG  . ARG B 1 67  ? 8.65200  -1.46000  185.81600 1.000 11.73000 ? 67  ARG B CG  1 
ATOM   2672 C CD  . ARG B 1 67  ? 7.89100  -0.89900  184.62500 1.000 15.70000 ? 67  ARG B CD  1 
ATOM   2673 N NE  . ARG B 1 67  ? 8.04500  0.54100   184.48800 1.000 23.18000 ? 67  ARG B NE  1 
ATOM   2674 C CZ  . ARG B 1 67  ? 7.30000  1.28200   183.67100 1.000 28.86000 ? 67  ARG B CZ  1 
ATOM   2675 N NH1 . ARG B 1 67  ? 6.35600  0.70900   182.92900 1.000 27.87000 ? 67  ARG B NH1 1 
ATOM   2676 N NH2 . ARG B 1 67  ? 7.49500  2.59200   183.59600 1.000 27.29000 ? 67  ARG B NH2 1 
ATOM   2677 N N   . PRO B 1 68  ? 6.77800  -4.68600  188.07000 1.000 11.94000 ? 68  PRO B N   1 
ATOM   2678 C CA  . PRO B 1 68  ? 5.91500  -5.85800  188.26900 1.000 11.91000 ? 68  PRO B CA  1 
ATOM   2679 C C   . PRO B 1 68  ? 5.60200  -6.55600  186.95500 1.000 14.87000 ? 68  PRO B C   1 
ATOM   2680 O O   . PRO B 1 68  ? 5.52000  -5.92900  185.89400 1.000 12.40000 ? 68  PRO B O   1 
ATOM   2681 C CB  . PRO B 1 68  ? 4.63700  -5.27300  188.88100 1.000 15.39000 ? 68  PRO B CB  1 
ATOM   2682 C CG  . PRO B 1 68  ? 4.95700  -3.89600  189.28800 1.000 16.27000 ? 68  PRO B CG  1 
ATOM   2683 C CD  . PRO B 1 68  ? 6.17400  -3.43800  188.57200 1.000 16.07000 ? 68  PRO B CD  1 
ATOM   2684 N N   . ALA B 1 69  ? 5.40200  -7.86700  187.04200 1.000 12.40000 ? 69  ALA B N   1 
ATOM   2685 C CA  . ALA B 1 69  ? 4.95600  -8.61800  185.87900 1.000 14.27000 ? 69  ALA B CA  1 
ATOM   2686 C C   . ALA B 1 69  ? 3.55800  -8.17100  185.47700 1.000 18.12000 ? 69  ALA B C   1 
ATOM   2687 O O   . ALA B 1 69  ? 2.74100  -7.77100  186.31200 1.000 18.65000 ? 69  ALA B O   1 
ATOM   2688 C CB  . ALA B 1 69  ? 4.96700  -10.12100 186.16600 1.000 15.22000 ? 69  ALA B CB  1 
ATOM   2689 N N   . ARG B 1 70  ? 3.29500  -8.21800  184.18000 1.000 16.49000 ? 70  ARG B N   1 
ATOM   2690 C CA  . ARG B 1 70  ? 1.98400  -7.85700  183.67600 1.000 20.70000 ? 70  ARG B CA  1 
ATOM   2691 C C   . ARG B 1 70  ? 1.00900  -9.01100  183.81900 1.000 21.95000 ? 70  ARG B C   1 
ATOM   2692 O O   . ARG B 1 70  ? 1.38500  -10.18600 183.75100 1.000 17.53000 ? 70  ARG B O   1 
ATOM   2693 C CB  . ARG B 1 70  ? 2.06600  -7.45900  182.21000 1.000 18.57000 ? 70  ARG B CB  1 
ATOM   2694 C CG  . ARG B 1 70  ? 2.65000  -6.10500  182.01500 1.000 20.40000 ? 70  ARG B CG  1 
ATOM   2695 C CD  . ARG B 1 70  ? 2.71100  -5.81100  180.55000 1.000 25.65000 ? 70  ARG B CD  1 
ATOM   2696 N NE  . ARG B 1 70  ? 3.37400  -4.54500  180.28700 1.000 25.74000 ? 70  ARG B NE  1 
ATOM   2697 C CZ  . ARG B 1 70  ? 2.80400  -3.53300  179.64800 1.000 25.59000 ? 70  ARG B CZ  1 
ATOM   2698 N NH1 . ARG B 1 70  ? 3.48300  -2.41000  179.45000 1.000 25.21000 ? 70  ARG B NH1 1 
ATOM   2699 N NH2 . ARG B 1 70  ? 1.55600  -3.64900  179.21400 1.000 27.05000 ? 70  ARG B NH2 1 
ATOM   2700 N N   . ALA B 1 71  ? -0.26200 -8.65700  184.00500 1.000 24.57000 ? 71  ALA B N   1 
ATOM   2701 C CA  . ALA B 1 71  ? -1.33600 -9.63400  183.94000 1.000 25.95000 ? 71  ALA B CA  1 
ATOM   2702 C C   . ALA B 1 71  ? -1.53200 -10.05600 182.49000 1.000 24.37000 ? 71  ALA B C   1 
ATOM   2703 O O   . ALA B 1 71  ? -1.75100 -9.21300  181.61200 1.000 31.29000 ? 71  ALA B O   1 
ATOM   2704 C CB  . ALA B 1 71  ? -2.62500 -9.04900  184.51800 1.000 27.29000 ? 71  ALA B CB  1 
ATOM   2705 N N   . LEU B 1 72  ? -1.40200 -11.34800 182.23100 1.000 18.30000 ? 72  LEU B N   1 
ATOM   2706 C CA  . LEU B 1 72  ? -1.66200 -11.89600 180.91300 1.000 15.80000 ? 72  LEU B CA  1 
ATOM   2707 C C   . LEU B 1 72  ? -2.64600 -13.04100 181.05700 1.000 14.14000 ? 72  LEU B C   1 
ATOM   2708 O O   . LEU B 1 72  ? -2.61000 -13.76700 182.05300 1.000 16.30000 ? 72  LEU B O   1 
ATOM   2709 C CB  . LEU B 1 72  ? -0.38400 -12.40900 180.23700 1.000 13.68000 ? 72  LEU B CB  1 
ATOM   2710 C CG  . LEU B 1 72  ? 0.77100  -11.42100 180.05100 1.000 11.48000 ? 72  LEU B CG  1 
ATOM   2711 C CD1 . LEU B 1 72  ? 1.95600  -12.16900 179.45300 1.000 16.35000 ? 72  LEU B CD1 1 
ATOM   2712 C CD2 . LEU B 1 72  ? 0.37900  -10.25700 179.16500 1.000 16.36000 ? 72  LEU B CD2 1 
ATOM   2713 N N   . PRO B 1 73  ? -3.53600 -13.22300 180.08100 1.000 14.19000 ? 73  PRO B N   1 
ATOM   2714 C CA  . PRO B 1 73  ? -4.48500 -14.34600 180.16400 1.000 16.01000 ? 73  PRO B CA  1 
ATOM   2715 C C   . PRO B 1 73  ? -3.82400 -15.70800 180.06400 1.000 16.78000 ? 73  PRO B C   1 
ATOM   2716 O O   . PRO B 1 73  ? -4.36300 -16.68200 180.60800 1.000 17.72000 ? 73  PRO B O   1 
ATOM   2717 C CB  . PRO B 1 73  ? -5.43100 -14.09500 178.98100 1.000 17.70000 ? 73  PRO B CB  1 
ATOM   2718 C CG  . PRO B 1 73  ? -4.65900 -13.23700 178.05500 1.000 17.28000 ? 73  PRO B CG  1 
ATOM   2719 C CD  . PRO B 1 73  ? -3.78800 -12.37100 178.90900 1.000 13.80000 ? 73  PRO B CD  1 
ATOM   2720 N N   . VAL B 1 74  ? -2.67900 -15.81500 179.39100 1.000 13.18000 ? 74  VAL B N   1 
ATOM   2721 C CA  . VAL B 1 74  ? -1.96900 -17.08000 179.24100 1.000 12.93000 ? 74  VAL B CA  1 
ATOM   2722 C C   . VAL B 1 74  ? -0.58400 -16.92000 179.84500 1.000 16.35000 ? 74  VAL B C   1 
ATOM   2723 O O   . VAL B 1 74  ? 0.25100  -16.17300 179.31800 1.000 10.97000 ? 74  VAL B O   1 
ATOM   2724 C CB  . VAL B 1 74  ? -1.87200 -17.52500 177.77600 1.000 11.85000 ? 74  VAL B CB  1 
ATOM   2725 C CG1 . VAL B 1 74  ? -1.03500 -18.79200 177.66000 1.000 12.84000 ? 74  VAL B CG1 1 
ATOM   2726 C CG2 . VAL B 1 74  ? -3.25900 -17.73900 177.20100 1.000 16.94000 ? 74  VAL B CG2 1 
ATOM   2727 N N   . ILE B 1 75  ? -0.35100 -17.60200 180.96100 1.000 10.36000 ? 75  ILE B N   1 
ATOM   2728 C CA  . ILE B 1 75  ? 0.98300  -17.81100 181.51600 1.000 9.95000  ? 75  ILE B CA  1 
ATOM   2729 C C   . ILE B 1 75  ? 0.99900  -19.26600 181.95700 1.000 15.30000 ? 75  ILE B C   1 
ATOM   2730 O O   . ILE B 1 75  ? 0.39900  -19.61400 182.97800 1.000 17.16000 ? 75  ILE B O   1 
ATOM   2731 C CB  . ILE B 1 75  ? 1.29600  -16.86500 182.69000 1.000 10.73000 ? 75  ILE B CB  1 
ATOM   2732 C CG1 . ILE B 1 75  ? 1.18800  -15.39500 182.27500 1.000 12.10000 ? 75  ILE B CG1 1 
ATOM   2733 C CG2 . ILE B 1 75  ? 2.70200  -17.15200 183.24200 1.000 14.19000 ? 75  ILE B CG2 1 
ATOM   2734 C CD1 . ILE B 1 75  ? 1.46100  -14.41600 183.40400 1.000 16.18000 ? 75  ILE B CD1 1 
ATOM   2735 N N   . ARG B 1 76  ? 1.64600  -20.13700 181.18800 1.000 10.72000 ? 76  ARG B N   1 
ATOM   2736 C CA  . ARG B 1 76  ? 1.42400  -21.57000 181.34700 1.000 13.16000 ? 76  ARG B CA  1 
ATOM   2737 C C   . ARG B 1 76  ? 2.74500  -22.32200 181.36200 1.000 14.31000 ? 76  ARG B C   1 
ATOM   2738 O O   . ARG B 1 76  ? 3.57400  -22.14100 180.46800 1.000 11.33000 ? 76  ARG B O   1 
ATOM   2739 C CB  . ARG B 1 76  ? 0.52300  -22.10100 180.22400 1.000 14.88000 ? 76  ARG B CB  1 
ATOM   2740 C CG  . ARG B 1 76  ? 0.23500  -23.59300 180.30300 1.000 19.23000 ? 76  ARG B CG  1 
ATOM   2741 C CD  . ARG B 1 76  ? -1.04300 -23.95700 179.54200 1.000 19.23000 ? 76  ARG B CD  1 
ATOM   2742 N NE  . ARG B 1 76  ? -0.90500 -23.81800 178.09400 1.000 19.75000 ? 76  ARG B NE  1 
ATOM   2743 C CZ  . ARG B 1 76  ? -0.31200 -24.70800 177.30100 1.000 24.63000 ? 76  ARG B CZ  1 
ATOM   2744 N NH1 . ARG B 1 76  ? -0.24900 -24.48700 175.99500 1.000 20.72000 ? 76  ARG B NH1 1 
ATOM   2745 N NH2 . ARG B 1 76  ? 0.21300  -25.81900 177.80700 1.000 23.33000 ? 76  ARG B NH2 1 
ATOM   2746 N N   . ASP B 1 77  ? 2.93500  -23.16700 182.37300 1.000 10.82000 ? 77  ASP B N   1 
ATOM   2747 C CA  . ASP B 1 77  ? 4.12100  -24.00900 182.44000 1.000 12.75000 ? 77  ASP B CA  1 
ATOM   2748 C C   . ASP B 1 77  ? 3.91100  -25.27700 181.63100 1.000 15.25000 ? 77  ASP B C   1 
ATOM   2749 O O   . ASP B 1 77  ? 2.84400  -25.89200 181.68800 1.000 15.44000 ? 77  ASP B O   1 
ATOM   2750 C CB  . ASP B 1 77  ? 4.44700  -24.38200 183.88700 1.000 14.84000 ? 77  ASP B CB  1 
ATOM   2751 C CG  . ASP B 1 77  ? 4.91700  -23.19200 184.71200 1.000 23.89000 ? 77  ASP B CG  1 
ATOM   2752 O OD1 . ASP B 1 77  ? 5.78800  -22.44000 184.23400 1.000 24.28000 ? 77  ASP B OD1 1 
ATOM   2753 O OD2 . ASP B 1 77  ? 4.42100  -23.01500 185.84600 1.000 26.59000 ? 77  ASP B OD2 1 
ATOM   2754 N N   . LEU B 1 78  ? 4.93900  -25.67600 180.88700 1.000 12.04000 ? 78  LEU B N   1 
ATOM   2755 C CA  . LEU B 1 78  ? 4.90300  -26.93100 180.14400 1.000 12.03000 ? 78  LEU B CA  1 
ATOM   2756 C C   . LEU B 1 78  ? 6.33700  -27.41100 179.96000 1.000 15.51000 ? 78  LEU B C   1 
ATOM   2757 O O   . LEU B 1 78  ? 7.27900  -26.83200 180.50900 1.000 15.06000 ? 78  LEU B O   1 
ATOM   2758 C CB  . LEU B 1 78  ? 4.16100  -26.76700 178.81000 1.000 16.00000 ? 78  LEU B CB  1 
ATOM   2759 C CG  . LEU B 1 78  ? 4.84700  -25.95300 177.70700 1.000 15.15000 ? 78  LEU B CG  1 
ATOM   2760 C CD1 . LEU B 1 78  ? 4.32700  -26.37900 176.34400 1.000 20.79000 ? 78  LEU B CD1 1 
ATOM   2761 C CD2 . LEU B 1 78  ? 4.64100  -24.44600 177.91500 1.000 15.41000 ? 78  LEU B CD2 1 
ATOM   2762 N N   . SER B 1 79  ? 6.50600  -28.49200 179.20700 1.000 12.86000 ? 79  SER B N   1 
ATOM   2763 C CA  . SER B 1 79  ? 7.83800  -29.03700 178.98600 1.000 12.84000 ? 79  SER B CA  1 
ATOM   2764 C C   . SER B 1 79  ? 7.89900  -29.65000 177.59700 1.000 15.98000 ? 79  SER B C   1 
ATOM   2765 O O   . SER B 1 79  ? 6.87100  -29.92500 176.97300 1.000 18.70000 ? 79  SER B O   1 
ATOM   2766 C CB  . SER B 1 79  ? 8.21000  -30.07400 180.05600 1.000 22.23000 ? 79  SER B CB  1 
ATOM   2767 O OG  . SER B 1 79  ? 7.50600  -31.28600 179.85600 1.000 27.37000 ? 79  SER B OG  1 
ATOM   2768 N N   . CYS B 1 80  ? 9.11800  -29.85800 177.11700 1.000 13.17000 ? 80  CYS B N   1 
ATOM   2769 C CA  . CYS B 1 80  ? 9.35000  -30.51500 175.84100 1.000 14.57000 ? 80  CYS B CA  1 
ATOM   2770 C C   . CYS B 1 80  ? 10.53000 -31.46200 175.97700 1.000 14.54000 ? 80  CYS B C   1 
ATOM   2771 O O   . CYS B 1 80  ? 11.35100 -31.31600 176.88900 1.000 13.73000 ? 80  CYS B O   1 
ATOM   2772 C CB  . CYS B 1 80  ? 9.60100  -29.49600 174.72100 1.000 11.88000 ? 80  CYS B CB  1 
ATOM   2773 S SG  . CYS B 1 80  ? 11.19900 -28.64800 174.75100 1.000 13.82000 ? 80  CYS B SG  1 
ATOM   2774 N N   . PRO B 1 81  ? 10.64600 -32.44800 175.08700 1.000 14.86000 ? 81  PRO B N   1 
ATOM   2775 C CA  . PRO B 1 81  ? 11.79000 -33.36300 175.16300 1.000 15.32000 ? 81  PRO B CA  1 
ATOM   2776 C C   . PRO B 1 81  ? 13.08700 -32.65100 174.82000 1.000 17.66000 ? 81  PRO B C   1 
ATOM   2777 O O   . PRO B 1 81  ? 13.13800 -31.79800 173.93000 1.000 16.60000 ? 81  PRO B O   1 
ATOM   2778 C CB  . PRO B 1 81  ? 11.46300 -34.44800 174.13000 1.000 18.58000 ? 81  PRO B CB  1 
ATOM   2779 C CG  . PRO B 1 81  ? 10.02500 -34.26800 173.77700 1.000 20.87000 ? 81  PRO B CG  1 
ATOM   2780 C CD  . PRO B 1 81  ? 9.69500  -32.82700 174.02700 1.000 17.45000 ? 81  PRO B CD  1 
ATOM   2781 N N   . GLY B 1 82  ? 14.14100 -33.01000 175.54200 1.000 14.80000 ? 82  GLY B N   1 
ATOM   2782 C CA  . GLY B 1 82  ? 15.46100 -32.50000 175.26500 1.000 14.02000 ? 82  GLY B CA  1 
ATOM   2783 C C   . GLY B 1 82  ? 16.48500 -33.61300 175.27100 1.000 21.17000 ? 82  GLY B C   1 
ATOM   2784 O O   . GLY B 1 82  ? 16.16600 -34.77800 175.52600 1.000 18.84000 ? 82  GLY B O   1 
ATOM   2785 N N   . PRO B 1 83  ? 17.74700 -33.26800 175.00800 1.000 17.29000 ? 83  PRO B N   1 
ATOM   2786 C CA  . PRO B 1 83  ? 18.78600 -34.30800 174.89800 1.000 18.03000 ? 83  PRO B CA  1 
ATOM   2787 C C   . PRO B 1 83  ? 19.05300 -35.07300 176.18700 1.000 23.97000 ? 83  PRO B C   1 
ATOM   2788 O O   . PRO B 1 83  ? 19.54800 -36.20500 176.11200 1.000 26.92000 ? 83  PRO B O   1 
ATOM   2789 C CB  . PRO B 1 83  ? 20.02900 -33.52700 174.44500 1.000 22.86000 ? 83  PRO B CB  1 
ATOM   2790 C CG  . PRO B 1 83  ? 19.72500 -32.08600 174.71400 1.000 20.54000 ? 83  PRO B CG  1 
ATOM   2791 C CD  . PRO B 1 83  ? 18.23700 -31.93000 174.63500 1.000 16.23000 ? 83  PRO B CD  1 
ATOM   2792 N N   . LYS B 1 84  ? 18.74700 -34.50900 177.36000 1.000 18.18000 ? 84  LYS B N   1 
ATOM   2793 C CA  . LYS B 1 84  ? 18.97500 -35.20300 178.62700 1.000 24.69000 ? 84  LYS B CA  1 
ATOM   2794 C C   . LYS B 1 84  ? 17.69800 -35.41900 179.43300 1.000 23.43000 ? 84  LYS B C   1 
ATOM   2795 O O   . LYS B 1 84  ? 17.77300 -35.81200 180.60400 1.000 30.49000 ? 84  LYS B O   1 
ATOM   2796 C CB  . LYS B 1 84  ? 19.99700 -34.44200 179.47600 1.000 29.03000 ? 84  LYS B CB  1 
ATOM   2797 C CG  . LYS B 1 84  ? 21.39300 -34.38700 178.86800 1.000 33.11000 ? 84  LYS B CG  1 
ATOM   2798 C CD  . LYS B 1 84  ? 22.05600 -35.76200 178.84900 1.000 41.42000 ? 84  LYS B CD  1 
ATOM   2799 C CE  . LYS B 1 84  ? 23.53500 -35.65400 178.52600 1.000 47.52000 ? 84  LYS B CE  1 
ATOM   2800 N NZ  . LYS B 1 84  ? 24.02700 -34.29000 178.85200 1.000 47.82000 ? 84  LYS B NZ  1 
ATOM   2801 N N   . GLY B 1 85  ? 16.54000 -35.18900 178.85100 1.000 18.97000 ? 85  GLY B N   1 
ATOM   2802 C CA  . GLY B 1 85  ? 15.28200 -35.29400 179.55500 1.000 20.39000 ? 85  GLY B CA  1 
ATOM   2803 C C   . GLY B 1 85  ? 14.40200 -34.11500 179.20900 1.000 19.87000 ? 85  GLY B C   1 
ATOM   2804 O O   . GLY B 1 85  ? 14.64900 -33.39400 178.24400 1.000 21.31000 ? 85  GLY B O   1 
ATOM   2805 N N   . GLU B 1 86  ? 13.36500 -33.91000 180.01300 1.000 16.52000 ? 86  GLU B N   1 
ATOM   2806 C CA  . GLU B 1 86  ? 12.41600 -32.84100 179.73200 1.000 17.05000 ? 86  GLU B CA  1 
ATOM   2807 C C   . GLU B 1 86  ? 13.04000 -31.47900 180.01400 1.000 16.89000 ? 86  GLU B C   1 
ATOM   2808 O O   . GLU B 1 86  ? 13.79700 -31.30900 180.97600 1.000 16.39000 ? 86  GLU B O   1 
ATOM   2809 C CB  . GLU B 1 86  ? 11.14900 -33.01800 180.56600 1.000 22.38000 ? 86  GLU B CB  1 
ATOM   2810 C CG  . GLU B 1 86  ? 10.32500 -34.25300 180.19000 1.000 28.69000 ? 86  GLU B CG  1 
ATOM   2811 C CD  . GLU B 1 86  ? 9.55200  -34.07300 178.89000 1.000 37.07000 ? 86  GLU B CD  1 
ATOM   2812 O OE1 . GLU B 1 86  ? 8.72500  -33.13500 178.80900 1.000 39.07000 ? 86  GLU B OE1 1 
ATOM   2813 O OE2 . GLU B 1 86  ? 9.76500  -34.86900 177.94600 1.000 35.71000 ? 86  GLU B OE2 1 
ATOM   2814 N N   . ILE B 1 87  ? 12.72200 -30.50500 179.16100 1.000 14.03000 ? 87  ILE B N   1 
ATOM   2815 C CA  . ILE B 1 87  ? 13.12300 -29.11100 179.34800 1.000 11.48000 ? 87  ILE B CA  1 
ATOM   2816 C C   . ILE B 1 87  ? 11.88800 -28.33200 179.77600 1.000 11.43000 ? 87  ILE B C   1 
ATOM   2817 O O   . ILE B 1 87  ? 10.88500 -28.30800 179.05300 1.000 11.39000 ? 87  ILE B O   1 
ATOM   2818 C CB  . ILE B 1 87  ? 13.70900 -28.50800 178.06200 1.000 11.36000 ? 87  ILE B CB  1 
ATOM   2819 C CG1 . ILE B 1 87  ? 14.92100 -29.31300 177.58400 1.000 10.20000 ? 87  ILE B CG1 1 
ATOM   2820 C CG2 . ILE B 1 87  ? 14.04100 -27.03200 178.28200 1.000 9.94000  ? 87  ILE B CG2 1 
ATOM   2821 C CD1 . ILE B 1 87  ? 15.30800 -29.01100 176.13600 1.000 12.12000 ? 87  ILE B CD1 1 
ATOM   2822 N N   . ALA B 1 88  ? 11.96100 -27.68000 180.93200 1.000 9.39000  ? 88  ALA B N   1 
ATOM   2823 C CA  . ALA B 1 88  ? 10.83100 -26.87900 181.39500 1.000 12.05000 ? 88  ALA B CA  1 
ATOM   2824 C C   . ALA B 1 88  ? 10.71600 -25.58900 180.58500 1.000 13.14000 ? 88  ALA B C   1 
ATOM   2825 O O   . ALA B 1 88  ? 11.71900 -24.93000 180.29400 1.000 9.39000  ? 88  ALA B O   1 
ATOM   2826 C CB  . ALA B 1 88  ? 10.98000 -26.55200 182.88000 1.000 13.79000 ? 88  ALA B CB  1 
ATOM   2827 N N   . LEU B 1 89  ? 9.47900  -25.23400 180.22800 1.000 9.41000  ? 89  LEU B N   1 
ATOM   2828 C CA  . LEU B 1 89  ? 9.17100  -24.05600 179.42100 1.000 8.46000  ? 89  LEU B CA  1 
ATOM   2829 C C   . LEU B 1 89  ? 8.05500  -23.25900 180.08700 1.000 10.76000 ? 89  LEU B C   1 
ATOM   2830 O O   . LEU B 1 89  ? 7.31000  -23.77700 180.92100 1.000 10.02000 ? 89  LEU B O   1 
ATOM   2831 C CB  . LEU B 1 89  ? 8.73700  -24.44600 177.99700 1.000 7.39000  ? 89  LEU B CB  1 
ATOM   2832 C CG  . LEU B 1 89  ? 9.64900  -25.38200 177.20100 1.000 7.97000  ? 89  LEU B CG  1 
ATOM   2833 C CD1 . LEU B 1 89  ? 8.93000  -25.89100 175.94000 1.000 10.47000 ? 89  LEU B CD1 1 
ATOM   2834 C CD2 . LEU B 1 89  ? 10.93000 -24.64700 176.82400 1.000 7.78000  ? 89  LEU B CD2 1 
ATOM   2835 N N   . ARG B 1 90  ? 7.93200  -21.98700 179.70900 1.000 9.42000  ? 90  ARG B N   1 
ATOM   2836 C CA  . ARG B 1 90  ? 6.79000  -21.18800 180.13700 1.000 7.15000  ? 90  ARG B CA  1 
ATOM   2837 C C   . ARG B 1 90  ? 6.28600  -20.37900 178.95500 1.000 10.85000 ? 90  ARG B C   1 
ATOM   2838 O O   . ARG B 1 90  ? 7.06200  -19.66300 178.31200 1.000 7.75000  ? 90  ARG B O   1 
ATOM   2839 C CB  . ARG B 1 90  ? 7.13700  -20.25800 181.30700 1.000 8.29000  ? 90  ARG B CB  1 
ATOM   2840 C CG  . ARG B 1 90  ? 5.90700  -19.61400 181.94700 1.000 9.47000  ? 90  ARG B CG  1 
ATOM   2841 C CD  . ARG B 1 90  ? 6.26200  -18.90300 183.24800 1.000 10.62000 ? 90  ARG B CD  1 
ATOM   2842 N NE  . ARG B 1 90  ? 6.63700  -19.83500 184.31200 1.000 10.18000 ? 90  ARG B NE  1 
ATOM   2843 C CZ  . ARG B 1 90  ? 7.27800  -19.46900 185.41900 1.000 12.12000 ? 90  ARG B CZ  1 
ATOM   2844 N NH1 . ARG B 1 90  ? 7.59200  -20.37200 186.34600 1.000 15.00000 ? 90  ARG B NH1 1 
ATOM   2845 N NH2 . ARG B 1 90  ? 7.61300  -18.19900 185.60100 1.000 11.53000 ? 90  ARG B NH2 1 
ATOM   2846 N N   . LEU B 1 91  ? 4.99100  -20.51600 178.66800 1.000 9.04000  ? 91  LEU B N   1 
ATOM   2847 C CA  . LEU B 1 91  ? 4.33400  -19.82700 177.56300 1.000 9.03000  ? 91  LEU B CA  1 
ATOM   2848 C C   . LEU B 1 91  ? 3.63800  -18.57600 178.08200 1.000 8.64000  ? 91  LEU B C   1 
ATOM   2849 O O   . LEU B 1 91  ? 2.88700  -18.64100 179.06300 1.000 9.54000  ? 91  LEU B O   1 
ATOM   2850 C CB  . LEU B 1 91  ? 3.31900  -20.74800 176.88000 1.000 7.40000  ? 91  LEU B CB  1 
ATOM   2851 C CG  . LEU B 1 91  ? 2.33200  -20.05600 175.93200 1.000 10.11000 ? 91  LEU B CG  1 
ATOM   2852 C CD1 . LEU B 1 91  ? 3.05500  -19.44800 174.73300 1.000 10.32000 ? 91  LEU B CD1 1 
ATOM   2853 C CD2 . LEU B 1 91  ? 1.24100  -21.03500 175.46000 1.000 13.75000 ? 91  LEU B CD2 1 
ATOM   2854 N N   . TYR B 1 92  ? 3.88500  -17.44600 177.41700 1.000 8.01000  ? 92  TYR B N   1 
ATOM   2855 C CA  . TYR B 1 92  ? 3.27300  -16.16200 177.73500 1.000 8.61000  ? 92  TYR B CA  1 
ATOM   2856 C C   . TYR B 1 92  ? 2.47400  -15.68800 176.53200 1.000 10.38000 ? 92  TYR B C   1 
ATOM   2857 O O   . TYR B 1 92  ? 2.98600  -15.70200 175.41000 1.000 10.71000 ? 92  TYR B O   1 
ATOM   2858 C CB  . TYR B 1 92  ? 4.32700  -15.09700 178.05800 1.000 6.96000  ? 92  TYR B CB  1 
ATOM   2859 C CG  . TYR B 1 92  ? 5.24100  -15.38000 179.23200 1.000 9.79000  ? 92  TYR B CG  1 
ATOM   2860 C CD1 . TYR B 1 92  ? 6.27000  -16.31300 179.13400 1.000 5.70000  ? 92  TYR B CD1 1 
ATOM   2861 C CD2 . TYR B 1 92  ? 5.09400  -14.68100 180.42600 1.000 9.93000  ? 92  TYR B CD2 1 
ATOM   2862 C CE1 . TYR B 1 92  ? 7.12400  -16.55900 180.21800 1.000 7.45000  ? 92  TYR B CE1 1 
ATOM   2863 C CE2 . TYR B 1 92  ? 5.93400  -14.91900 181.50600 1.000 9.14000  ? 92  TYR B CE2 1 
ATOM   2864 C CZ  . TYR B 1 92  ? 6.94800  -15.85100 181.38900 1.000 7.97000  ? 92  TYR B CZ  1 
ATOM   2865 O OH  . TYR B 1 92  ? 7.77800  -16.07400 182.46000 1.000 10.49000 ? 92  TYR B OH  1 
ATOM   2866 N N   . ASP B 1 93  ? 1.23500  -15.24000 176.75500 1.000 9.01000  ? 93  ASP B N   1 
ATOM   2867 C CA  . ASP B 1 93  ? 0.49500  -14.67400 175.60700 1.000 11.44000 ? 93  ASP B CA  1 
ATOM   2868 C C   . ASP B 1 93  ? -0.46700 -13.62200 176.13700 1.000 12.70000 ? 93  ASP B C   1 
ATOM   2869 O O   . ASP B 1 93  ? -1.26800 -13.93100 177.03900 1.000 12.73000 ? 93  ASP B O   1 
ATOM   2870 C CB  . ASP B 1 93  ? -0.27200 -15.72500 174.80100 1.000 11.28000 ? 93  ASP B CB  1 
ATOM   2871 C CG  . ASP B 1 93  ? -0.67200 -15.22900 173.40400 1.000 15.12000 ? 93  ASP B CG  1 
ATOM   2872 O OD1 . ASP B 1 93  ? -0.89900 -14.01000 173.23600 1.000 16.16000 ? 93  ASP B OD1 1 
ATOM   2873 O OD2 . ASP B 1 93  ? -0.76700 -16.05700 172.46800 1.000 15.30000 ? 93  ASP B OD2 1 
ATOM   2874 N N   . PRO B 1 94  ? -0.40400 -12.38600 175.63100 1.000 12.31000 ? 94  PRO B N   1 
ATOM   2875 C CA  . PRO B 1 94  ? -1.37900 -11.37700 176.05800 1.000 13.27000 ? 94  PRO B CA  1 
ATOM   2876 C C   . PRO B 1 94  ? -2.76600 -11.61700 175.50300 1.000 16.54000 ? 94  PRO B C   1 
ATOM   2877 O O   . PRO B 1 94  ? -3.71500 -10.95700 175.94500 1.000 16.86000 ? 94  PRO B O   1 
ATOM   2878 C CB  . PRO B 1 94  ? -0.78400 -10.06700 175.52700 1.000 16.51000 ? 94  PRO B CB  1 
ATOM   2879 C CG  . PRO B 1 94  ? 0.01500  -10.48400 174.34100 1.000 12.67000 ? 94  PRO B CG  1 
ATOM   2880 C CD  . PRO B 1 94  ? 0.59500  -11.82700 174.69900 1.000 11.81000 ? 94  PRO B CD  1 
ATOM   2881 N N   . ARG B 1 95  ? -2.91900 -12.54400 174.56500 1.000 17.62000 ? 95  ARG B N   1 
ATOM   2882 C CA  . ARG B 1 95  ? -4.21000 -12.80600 173.95100 1.000 20.20000 ? 95  ARG B CA  1 
ATOM   2883 C C   . ARG B 1 95  ? -4.85400 -14.04500 174.55000 1.000 20.86000 ? 95  ARG B C   1 
ATOM   2884 O O   . ARG B 1 95  ? -4.20000 -15.07400 174.76000 1.000 18.71000 ? 95  ARG B O   1 
ATOM   2885 C CB  . ARG B 1 95  ? -4.07700 -12.97300 172.44400 1.000 19.18000 ? 95  ARG B CB  1 
ATOM   2886 C CG  . ARG B 1 95  ? -3.96600 -11.65900 171.71400 1.000 21.05000 ? 95  ARG B CG  1 
ATOM   2887 C CD  . ARG B 1 95  ? -4.21800 -11.86000 170.24600 1.000 22.64000 ? 95  ARG B CD  1 
ATOM   2888 N NE  . ARG B 1 95  ? -3.55900 -10.85200 169.42300 1.000 31.01000 ? 95  ARG B NE  1 
ATOM   2889 C CZ  . ARG B 1 95  ? -3.39400 -10.96000 168.10400 1.000 34.40000 ? 95  ARG B CZ  1 
ATOM   2890 N NH1 . ARG B 1 95  ? -3.83800 -12.03600 167.46100 1.000 31.52000 ? 95  ARG B NH1 1 
ATOM   2891 N NH2 . ARG B 1 95  ? -2.78100 -9.99600  167.42600 1.000 27.94000 ? 95  ARG B NH2 1 
ATOM   2892 N N   . GLU B 1 96  ? -6.15100 -13.91300 174.82900 1.000 25.98000 ? 96  GLU B N   1 
ATOM   2893 C CA  . GLU B 1 96  ? -6.97400 -15.02100 175.29100 1.000 31.74000 ? 96  GLU B CA  1 
ATOM   2894 C C   . GLU B 1 96  ? -6.95200 -16.17300 174.29300 1.000 33.54000 ? 96  GLU B C   1 
ATOM   2895 O O   . GLU B 1 96  ? -6.75300 -17.33400 174.66800 1.000 31.57000 ? 96  GLU B O   1 
ATOM   2896 C CB  . GLU B 1 96  ? -8.40400 -14.51000 175.52500 1.000 34.87000 ? 96  GLU B CB  1 
ATOM   2897 C CG  . GLU B 1 96  ? -9.10000 -13.83700 174.29400 1.000 44.42000 ? 96  GLU B CG  1 
ATOM   2898 C CD  . GLU B 1 96  ? -8.42700 -12.54500 173.79500 1.000 40.49000 ? 96  GLU B CD  1 
ATOM   2899 O OE1 . GLU B 1 96  ? -8.08400 -11.67600 174.62700 1.000 42.49000 ? 96  GLU B OE1 1 
ATOM   2900 O OE2 . GLU B 1 96  ? -8.22800 -12.40900 172.56500 1.000 36.54000 ? 96  GLU B OE2 1 
ATOM   2901 N N   . SER B 1 97  ? -7.13700 -15.86700 173.01000 1.000 28.51000 ? 97  SER B N   1 
ATOM   2902 C CA  . SER B 1 97  ? -7.17300 -16.86300 171.95200 1.000 34.98000 ? 97  SER B CA  1 
ATOM   2903 C C   . SER B 1 97  ? -6.26200 -16.41000 170.82300 1.000 34.79000 ? 97  SER B C   1 
ATOM   2904 O O   . SER B 1 97  ? -6.30900 -15.24800 170.40800 1.000 41.31000 ? 97  SER B O   1 
ATOM   2905 C CB  . SER B 1 97  ? -8.59800 -17.06600 171.42500 1.000 38.16000 ? 97  SER B CB  1 
ATOM   2906 O OG  . SER B 1 97  ? -9.54900 -16.98400 172.47300 1.000 41.15000 ? 97  SER B OG  1 
ATOM   2907 N N   . ARG B 1 98  ? -5.43200 -17.32100 170.34000 1.000 36.23000 ? 98  ARG B N   1 
ATOM   2908 C CA  . ARG B 1 98  ? -4.65100 -17.07000 169.14400 1.000 33.29000 ? 98  ARG B CA  1 
ATOM   2909 C C   . ARG B 1 98  ? -4.83600 -18.25900 168.21200 1.000 30.07000 ? 98  ARG B C   1 
ATOM   2910 O O   . ARG B 1 98  ? -4.28300 -18.29800 167.11800 1.000 43.53000 ? 98  ARG B O   1 
ATOM   2911 C CB  . ARG B 1 98  ? -3.17000 -16.85000 169.48000 1.000 29.32000 ? 98  ARG B CB  1 
ATOM   2912 C CG  . ARG B 1 98  ? -2.47600 -15.84200 168.56500 1.000 24.99000 ? 98  ARG B CG  1 
ATOM   2913 C CD  . ARG B 1 98  ? -1.04000 -15.56100 168.99400 1.000 19.27000 ? 98  ARG B CD  1 
ATOM   2914 N NE  . ARG B 1 98  ? -0.93600 -14.58900 170.08200 1.000 15.21000 ? 98  ARG B NE  1 
ATOM   2915 C CZ  . ARG B 1 98  ? -0.68600 -13.29100 169.92000 1.000 16.79000 ? 98  ARG B CZ  1 
ATOM   2916 N NH1 . ARG B 1 98  ? -0.58800 -12.49600 170.97900 1.000 15.78000 ? 98  ARG B NH1 1 
ATOM   2917 N NH2 . ARG B 1 98  ? -0.52600 -12.78000 168.70400 1.000 19.01000 ? 98  ARG B NH2 1 
ATOM   2918 N N   . GLY B 1 100 ? -4.49400 -18.45400 164.38200 1.000 22.08000 ? 100 GLY B N   1 
ATOM   2919 C CA  . GLY B 1 100 ? -3.85100 -18.47800 163.07700 1.000 22.94000 ? 100 GLY B CA  1 
ATOM   2920 C C   . GLY B 1 100 ? -2.33300 -18.40700 163.13100 1.000 25.57000 ? 100 GLY B C   1 
ATOM   2921 O O   . GLY B 1 100 ? -1.76100 -18.35900 164.21900 1.000 22.57000 ? 100 GLY B O   1 
ATOM   2922 N N   . PRO B 1 101 ? -1.68400 -18.40600 161.96300 1.000 22.42000 ? 101 PRO B N   1 
ATOM   2923 C CA  . PRO B 1 101 ? -0.21400 -18.36600 161.93000 1.000 21.46000 ? 101 PRO B CA  1 
ATOM   2924 C C   . PRO B 1 101 ? 0.33600  -17.12600 162.62500 1.000 20.92000 ? 101 PRO B C   1 
ATOM   2925 O O   . PRO B 1 101 ? -0.24400 -16.03900 162.55000 1.000 18.64000 ? 101 PRO B O   1 
ATOM   2926 C CB  . PRO B 1 101 ? 0.10700  -18.35700 160.43100 1.000 25.20000 ? 101 PRO B CB  1 
ATOM   2927 C CG  . PRO B 1 101 ? -1.09300 -18.98600 159.78500 1.000 23.70000 ? 101 PRO B CG  1 
ATOM   2928 C CD  . PRO B 1 101 ? -2.26700 -18.55300 160.61800 1.000 25.97000 ? 101 PRO B CD  1 
ATOM   2929 N N   . THR B 1 102 ? 1.47000  -17.29900 163.30800 1.000 15.78000 ? 102 THR B N   1 
ATOM   2930 C CA  . THR B 1 102 ? 2.07100  -16.21100 164.06800 1.000 14.20000 ? 102 THR B CA  1 
ATOM   2931 C C   . THR B 1 102 ? 3.55600  -16.48800 164.23700 1.000 15.16000 ? 102 THR B C   1 
ATOM   2932 O O   . THR B 1 102 ? 3.95300  -17.65100 164.36600 1.000 12.74000 ? 102 THR B O   1 
ATOM   2933 C CB  . THR B 1 102 ? 1.40000  -16.05500 165.44800 1.000 14.39000 ? 102 THR B CB  1 
ATOM   2934 O OG1 . THR B 1 102 ? 2.05500  -15.01500 166.19000 1.000 11.95000 ? 102 THR B OG1 1 
ATOM   2935 C CG2 . THR B 1 102 ? 1.46700  -17.36500 166.25400 1.000 13.23000 ? 102 THR B CG2 1 
ATOM   2936 N N   . PRO B 1 103 ? 4.40100  -15.45600 164.23900 1.000 12.93000 ? 103 PRO B N   1 
ATOM   2937 C CA  . PRO B 1 103 ? 5.75000  -15.64600 164.78000 1.000 11.82000 ? 103 PRO B CA  1 
ATOM   2938 C C   . PRO B 1 103 ? 5.63400  -16.01800 166.24800 1.000 10.14000 ? 103 PRO B C   1 
ATOM   2939 O O   . PRO B 1 103 ? 4.66700  -15.66100 166.92600 1.000 11.14000 ? 103 PRO B O   1 
ATOM   2940 C CB  . PRO B 1 103 ? 6.43100  -14.28000 164.59600 1.000 13.42000 ? 103 PRO B CB  1 
ATOM   2941 C CG  . PRO B 1 103 ? 5.50100  -13.44800 163.77900 1.000 14.71000 ? 103 PRO B CG  1 
ATOM   2942 C CD  . PRO B 1 103 ? 4.14600  -14.07400 163.79800 1.000 15.74000 ? 103 PRO B CD  1 
ATOM   2943 N N   . VAL B 1 104 ? 6.61200  -16.77600 166.73600 1.000 9.91000  ? 104 VAL B N   1 
ATOM   2944 C CA  . VAL B 1 104 ? 6.68200  -17.12400 168.14800 1.000 8.09000  ? 104 VAL B CA  1 
ATOM   2945 C C   . VAL B 1 104 ? 8.03300  -16.68100 168.68200 1.000 6.25000  ? 104 VAL B C   1 
ATOM   2946 O O   . VAL B 1 104 ? 9.07400  -17.03800 168.11700 1.000 8.15000  ? 104 VAL B O   1 
ATOM   2947 C CB  . VAL B 1 104 ? 6.47000  -18.62900 168.38400 1.000 10.39000 ? 104 VAL B CB  1 
ATOM   2948 C CG1 . VAL B 1 104 ? 6.52000  -18.92800 169.88200 1.000 9.78000  ? 104 VAL B CG1 1 
ATOM   2949 C CG2 . VAL B 1 104 ? 5.12600  -19.06300 167.79200 1.000 12.84000 ? 104 VAL B CG2 1 
ATOM   2950 N N   . ILE B 1 105 ? 8.01100  -15.91500 169.77100 1.000 5.97000  ? 105 ILE B N   1 
ATOM   2951 C CA  . ILE B 1 105 ? 9.24000  -15.47800 170.42200 1.000 7.61000  ? 105 ILE B CA  1 
ATOM   2952 C C   . ILE B 1 105 ? 9.75900  -16.61000 171.29600 1.000 8.93000  ? 105 ILE B C   1 
ATOM   2953 O O   . ILE B 1 105 ? 9.00700  -17.19500 172.07900 1.000 7.38000  ? 105 ILE B O   1 
ATOM   2954 C CB  . ILE B 1 105 ? 8.99300  -14.21100 171.25300 1.000 7.76000  ? 105 ILE B CB  1 
ATOM   2955 C CG1 . ILE B 1 105 ? 8.44400  -13.08900 170.36500 1.000 7.85000  ? 105 ILE B CG1 1 
ATOM   2956 C CG2 . ILE B 1 105 ? 10.27900 -13.76200 171.91900 1.000 8.48000  ? 105 ILE B CG2 1 
ATOM   2957 C CD1 . ILE B 1 105 ? 7.86600  -11.92900 171.16900 1.000 9.41000  ? 105 ILE B CD1 1 
ATOM   2958 N N   . THR B 1 106 ? 11.04100 -16.93300 171.15200 1.000 6.86000  ? 106 THR B N   1 
ATOM   2959 C CA  . THR B 1 106 ? 11.71300 -17.89800 172.01400 1.000 6.66000  ? 106 THR B CA  1 
ATOM   2960 C C   . THR B 1 106 ? 12.76200 -17.13200 172.81100 1.000 6.29000  ? 106 THR B C   1 
ATOM   2961 O O   . THR B 1 106 ? 13.65400 -16.51000 172.22200 1.000 7.14000  ? 106 THR B O   1 
ATOM   2962 C CB  . THR B 1 106 ? 12.34600 -19.02300 171.19200 1.000 9.65000  ? 106 THR B CB  1 
ATOM   2963 O OG1 . THR B 1 106 ? 11.33200 -19.66500 170.39400 1.000 9.64000  ? 106 THR B OG1 1 
ATOM   2964 C CG2 . THR B 1 106 ? 12.99500 -20.04800 172.10800 1.000 9.60000  ? 106 THR B CG2 1 
ATOM   2965 N N   . PHE B 1 107 ? 12.63400 -17.15300 174.13700 1.000 6.01000  ? 107 PHE B N   1 
ATOM   2966 C CA  . PHE B 1 107 ? 13.39900 -16.29200 175.03300 1.000 5.52000  ? 107 PHE B CA  1 
ATOM   2967 C C   . PHE B 1 107 ? 14.37100 -17.12800 175.85900 1.000 5.98000  ? 107 PHE B C   1 
ATOM   2968 O O   . PHE B 1 107 ? 13.97700 -18.14400 176.44100 1.000 6.83000  ? 107 PHE B O   1 
ATOM   2969 C CB  . PHE B 1 107 ? 12.46100 -15.51000 175.96300 1.000 6.95000  ? 107 PHE B CB  1 
ATOM   2970 C CG  . PHE B 1 107 ? 13.17900 -14.64300 176.96600 1.000 7.17000  ? 107 PHE B CG  1 
ATOM   2971 C CD1 . PHE B 1 107 ? 13.54400 -15.14700 178.21400 1.000 6.51000  ? 107 PHE B CD1 1 
ATOM   2972 C CD2 . PHE B 1 107 ? 13.48100 -13.32300 176.66900 1.000 9.64000  ? 107 PHE B CD2 1 
ATOM   2973 C CE1 . PHE B 1 107 ? 14.21100 -14.36200 179.13300 1.000 8.77000  ? 107 PHE B CE1 1 
ATOM   2974 C CE2 . PHE B 1 107 ? 14.14900 -12.52000 177.59900 1.000 12.27000 ? 107 PHE B CE2 1 
ATOM   2975 C CZ  . PHE B 1 107 ? 14.51600 -13.04800 178.82800 1.000 9.94000  ? 107 PHE B CZ  1 
ATOM   2976 N N   . PHE B 1 108 ? 15.62900 -16.68900 175.92600 1.000 5.15000  ? 108 PHE B N   1 
ATOM   2977 C CA  . PHE B 1 108 ? 16.66100 -17.35300 176.72700 1.000 6.54000  ? 108 PHE B CA  1 
ATOM   2978 C C   . PHE B 1 108 ? 17.17700 -16.38500 177.78600 1.000 5.58000  ? 108 PHE B C   1 
ATOM   2979 O O   . PHE B 1 108 ? 17.73600 -15.33600 177.45000 1.000 5.69000  ? 108 PHE B O   1 
ATOM   2980 C CB  . PHE B 1 108 ? 17.81600 -17.83600 175.84100 1.000 5.39000  ? 108 PHE B CB  1 
ATOM   2981 C CG  . PHE B 1 108 ? 17.37800 -18.51800 174.56400 1.000 5.91000  ? 108 PHE B CG  1 
ATOM   2982 C CD1 . PHE B 1 108 ? 16.70600 -19.73600 174.60400 1.000 6.14000  ? 108 PHE B CD1 1 
ATOM   2983 C CD2 . PHE B 1 108 ? 17.66700 -17.95200 173.32100 1.000 7.19000  ? 108 PHE B CD2 1 
ATOM   2984 C CE1 . PHE B 1 108 ? 16.30600 -20.37200 173.42600 1.000 7.48000  ? 108 PHE B CE1 1 
ATOM   2985 C CE2 . PHE B 1 108 ? 17.28000 -18.58700 172.13700 1.000 6.89000  ? 108 PHE B CE2 1 
ATOM   2986 C CZ  . PHE B 1 108 ? 16.59700 -19.79700 172.19200 1.000 7.13000  ? 108 PHE B CZ  1 
ATOM   2987 N N   . HIS B 1 109 ? 17.01600 -16.74300 179.06000 1.000 5.45000  ? 109 HIS B N   1 
ATOM   2988 C CA  . HIS B 1 109 ? 17.37600 -15.82700 180.14200 1.000 6.32000  ? 109 HIS B CA  1 
ATOM   2989 C C   . HIS B 1 109 ? 18.89400 -15.74100 180.33200 1.000 6.45000  ? 109 HIS B C   1 
ATOM   2990 O O   . HIS B 1 109 ? 19.66100 -16.63900 179.95600 1.000 8.07000  ? 109 HIS B O   1 
ATOM   2991 C CB  . HIS B 1 109 ? 16.72300 -16.26800 181.45500 1.000 4.90000  ? 109 HIS B CB  1 
ATOM   2992 C CG  . HIS B 1 109 ? 17.27200 -17.55600 181.98800 1.000 6.77000  ? 109 HIS B CG  1 
ATOM   2993 N ND1 . HIS B 1 109 ? 18.43600 -17.61600 182.72600 1.000 5.82000  ? 109 HIS B ND1 1 
ATOM   2994 C CD2 . HIS B 1 109 ? 16.82300 -18.83200 181.88800 1.000 6.23000  ? 109 HIS B CD2 1 
ATOM   2995 C CE1 . HIS B 1 109 ? 18.68300 -18.87200 183.05400 1.000 6.46000  ? 109 HIS B CE1 1 
ATOM   2996 N NE2 . HIS B 1 109 ? 17.71800 -19.62900 182.56200 1.000 5.89000  ? 109 HIS B NE2 1 
ATOM   2997 N N   . GLY B 1 110 ? 19.32300 -14.64100 180.95400 1.000 6.42000  ? 110 GLY B N   1 
ATOM   2998 C CA  . GLY B 1 110 ? 20.71000 -14.47400 181.33300 1.000 8.18000  ? 110 GLY B CA  1 
ATOM   2999 C C   . GLY B 1 110 ? 21.01500 -15.09200 182.69200 1.000 8.50000  ? 110 GLY B C   1 
ATOM   3000 O O   . GLY B 1 110 ? 20.16700 -15.69700 183.34000 1.000 7.77000  ? 110 GLY B O   1 
ATOM   3001 N N   . GLY B 1 111 ? 22.26600 -14.92600 183.11600 1.000 9.78000  ? 111 GLY B N   1 
ATOM   3002 C CA  . GLY B 1 111 ? 22.74400 -15.52600 184.35000 1.000 6.95000  ? 111 GLY B CA  1 
ATOM   3003 C C   . GLY B 1 111 ? 24.03400 -16.30500 184.16500 1.000 7.21000  ? 111 GLY B C   1 
ATOM   3004 O O   . GLY B 1 111 ? 24.36400 -17.17600 184.97700 1.000 5.86000  ? 111 GLY B O   1 
ATOM   3005 N N   . GLY B 1 112 ? 24.78200 -16.00400 183.10500 1.000 6.63000  ? 112 GLY B N   1 
ATOM   3006 C CA  . GLY B 1 112 ? 26.08100 -16.62700 182.92000 1.000 8.82000  ? 112 GLY B CA  1 
ATOM   3007 C C   . GLY B 1 112 ? 26.07100 -18.10800 182.64100 1.000 10.38000 ? 112 GLY B C   1 
ATOM   3008 O O   . GLY B 1 112 ? 27.14000 -18.73100 182.68100 1.000 8.06000  ? 112 GLY B O   1 
ATOM   3009 N N   . PHE B 1 113 ? 24.90200 -18.67800 182.34600 1.000 7.16000  ? 113 PHE B N   1 
ATOM   3010 C CA  . PHE B 1 113 ? 24.63000 -20.11200 182.23400 1.000 5.83000  ? 113 PHE B CA  1 
ATOM   3011 C C   . PHE B 1 113 ? 24.70700 -20.82100 183.58800 1.000 6.66000  ? 113 PHE B C   1 
ATOM   3012 O O   . PHE B 1 113 ? 24.70400 -22.05800 183.63300 1.000 8.45000  ? 113 PHE B O   1 
ATOM   3013 C CB  . PHE B 1 113 ? 25.55300 -20.80000 181.22300 1.000 7.58000  ? 113 PHE B CB  1 
ATOM   3014 C CG  . PHE B 1 113 ? 25.37400 -20.30600 179.80900 1.000 8.17000  ? 113 PHE B CG  1 
ATOM   3015 C CD1 . PHE B 1 113 ? 24.15600 -20.44500 179.16300 1.000 8.13000  ? 113 PHE B CD1 1 
ATOM   3016 C CD2 . PHE B 1 113 ? 26.41800 -19.69000 179.13900 1.000 8.99000  ? 113 PHE B CD2 1 
ATOM   3017 C CE1 . PHE B 1 113 ? 23.99100 -19.98900 177.84700 1.000 9.45000  ? 113 PHE B CE1 1 
ATOM   3018 C CE2 . PHE B 1 113 ? 26.25500 -19.23900 177.83300 1.000 7.15000  ? 113 PHE B CE2 1 
ATOM   3019 C CZ  . PHE B 1 113 ? 25.04500 -19.38900 177.19700 1.000 7.16000  ? 113 PHE B CZ  1 
ATOM   3020 N N   . VAL B 1 114 ? 24.75100 -20.06700 184.68900 1.000 5.15000  ? 114 VAL B N   1 
ATOM   3021 C CA  . VAL B 1 114 ? 24.85200 -20.61800 186.03500 1.000 6.20000  ? 114 VAL B CA  1 
ATOM   3022 C C   . VAL B 1 114 ? 23.61300 -20.30500 186.86300 1.000 6.30000  ? 114 VAL B C   1 
ATOM   3023 O O   . VAL B 1 114 ? 23.09600 -21.17700 187.57500 1.000 6.30000  ? 114 VAL B O   1 
ATOM   3024 C CB  . VAL B 1 114 ? 26.11800 -20.10000 186.75900 1.000 6.54000  ? 114 VAL B CB  1 
ATOM   3025 C CG1 . VAL B 1 114 ? 26.17500 -20.59800 188.19700 1.000 5.65000  ? 114 VAL B CG1 1 
ATOM   3026 C CG2 . VAL B 1 114 ? 27.36800 -20.50000 185.99800 1.000 7.19000  ? 114 VAL B CG2 1 
ATOM   3027 N N   . ILE B 1 115 ? 23.12900 -19.06600 186.79800 1.000 6.81000  ? 115 ILE B N   1 
ATOM   3028 C CA  . ILE B 1 115 ? 21.97500 -18.64000 187.57600 1.000 5.01000  ? 115 ILE B CA  1 
ATOM   3029 C C   . ILE B 1 115 ? 20.87900 -18.19500 186.61800 1.000 7.83000  ? 115 ILE B C   1 
ATOM   3030 O O   . ILE B 1 115 ? 21.06300 -18.21600 185.39600 1.000 8.06000  ? 115 ILE B O   1 
ATOM   3031 C CB  . ILE B 1 115 ? 22.35400 -17.52100 188.56500 1.000 5.69000  ? 115 ILE B CB  1 
ATOM   3032 C CG1 . ILE B 1 115 ? 22.83700 -16.27000 187.82000 1.000 8.09000  ? 115 ILE B CG1 1 
ATOM   3033 C CG2 . ILE B 1 115 ? 23.44400 -18.01800 189.50600 1.000 6.75000  ? 115 ILE B CG2 1 
ATOM   3034 C CD1 . ILE B 1 115 ? 23.32100 -15.14200 188.74300 1.000 8.84000  ? 115 ILE B CD1 1 
ATOM   3035 N N   . GLY B 1 116 ? 19.73300 -17.80500 187.16600 1.000 7.03000  ? 116 GLY B N   1 
ATOM   3036 C CA  . GLY B 1 116 ? 18.59400 -17.42500 186.36100 1.000 6.92000  ? 116 GLY B CA  1 
ATOM   3037 C C   . GLY B 1 116 ? 17.69800 -18.61400 186.04700 1.000 6.90000  ? 116 GLY B C   1 
ATOM   3038 O O   . GLY B 1 116 ? 18.12200 -19.77000 186.02600 1.000 6.87000  ? 116 GLY B O   1 
ATOM   3039 N N   . ASP B 1 117 ? 16.43100 -18.31300 185.78700 1.000 5.61000  ? 117 ASP B N   1 
ATOM   3040 C CA  . ASP B 1 117 ? 15.45400 -19.36400 185.54100 1.000 7.55000  ? 117 ASP B CA  1 
ATOM   3041 C C   . ASP B 1 117 ? 14.17800 -18.75600 184.98100 1.000 9.37000  ? 117 ASP B C   1 
ATOM   3042 O O   . ASP B 1 117 ? 14.19700 -17.62500 184.48500 1.000 8.58000  ? 117 ASP B O   1 
ATOM   3043 C CB  . ASP B 1 117 ? 15.16700 -20.14400 186.83000 1.000 8.37000  ? 117 ASP B CB  1 
ATOM   3044 C CG  . ASP B 1 117 ? 14.84100 -19.22900 188.00600 1.000 17.70000 ? 117 ASP B CG  1 
ATOM   3045 O OD1 . ASP B 1 117 ? 13.97600 -18.33700 187.86100 1.000 11.00000 ? 117 ASP B OD1 1 
ATOM   3046 O OD2 . ASP B 1 117 ? 15.45700 -19.40000 189.08000 1.000 22.05000 ? 117 ASP B OD2 1 
ATOM   3047 N N   . LEU B 1 118 ? 13.06000 -19.48500 185.06200 1.000 7.88000  ? 118 LEU B N   1 
ATOM   3048 C CA  . LEU B 1 118 ? 11.82400 -18.92900 184.52300 1.000 8.38000  ? 118 LEU B CA  1 
ATOM   3049 C C   . LEU B 1 118 ? 11.27900 -17.80300 185.38600 1.000 11.32000 ? 118 LEU B C   1 
ATOM   3050 O O   . LEU B 1 118 ? 10.55100 -16.94700 184.87400 1.000 10.37000 ? 118 LEU B O   1 
ATOM   3051 C CB  . LEU B 1 118 ? 10.77100 -20.02300 184.36700 1.000 8.75000  ? 118 LEU B CB  1 
ATOM   3052 C CG  . LEU B 1 118 ? 11.15000 -21.15800 183.41600 1.000 7.16000  ? 118 LEU B CG  1 
ATOM   3053 C CD1 . LEU B 1 118 ? 10.05700 -22.22000 183.40400 1.000 10.28000 ? 118 LEU B CD1 1 
ATOM   3054 C CD2 . LEU B 1 118 ? 11.40100 -20.63000 182.00200 1.000 8.15000  ? 118 LEU B CD2 1 
ATOM   3055 N N   . ASP B 1 119 ? 11.62300 -17.77200 186.67300 1.000 8.28000  ? 119 ASP B N   1 
ATOM   3056 C CA  . ASP B 1 119 ? 11.10200 -16.72900 187.54800 1.000 9.36000  ? 119 ASP B CA  1 
ATOM   3057 C C   . ASP B 1 119 ? 11.97000 -15.47700 187.57400 1.000 6.97000  ? 119 ASP B C   1 
ATOM   3058 O O   . ASP B 1 119 ? 11.43200 -14.37800 187.74600 1.000 7.56000  ? 119 ASP B O   1 
ATOM   3059 C CB  . ASP B 1 119 ? 10.92400 -17.28600 188.96400 1.000 9.65000  ? 119 ASP B CB  1 
ATOM   3060 C CG  . ASP B 1 119 ? 9.87200  -18.39200 189.01600 1.000 18.14000 ? 119 ASP B CG  1 
ATOM   3061 O OD1 . ASP B 1 119 ? 8.83800  -18.26500 188.32400 1.000 16.40000 ? 119 ASP B OD1 1 
ATOM   3062 O OD2 . ASP B 1 119 ? 10.09000 -19.39700 189.72200 1.000 17.96000 ? 119 ASP B OD2 1 
ATOM   3063 N N   . THR B 1 120 ? 13.29000 -15.60200 187.38100 1.000 7.76000  ? 120 THR B N   1 
ATOM   3064 C CA  . THR B 1 120 ? 14.14800 -14.41700 187.45100 1.000 7.96000  ? 120 THR B CA  1 
ATOM   3065 C C   . THR B 1 120 ? 13.80600 -13.42000 186.35400 1.000 7.92000  ? 120 THR B C   1 
ATOM   3066 O O   . THR B 1 120 ? 13.90900 -12.20500 186.56000 1.000 8.47000  ? 120 THR B O   1 
ATOM   3067 C CB  . THR B 1 120 ? 15.62600 -14.80300 187.34500 1.000 8.18000  ? 120 THR B CB  1 
ATOM   3068 O OG1 . THR B 1 120 ? 15.84100 -15.51400 186.12200 1.000 6.30000  ? 120 THR B OG1 1 
ATOM   3069 C CG2 . THR B 1 120 ? 16.04900 -15.68200 188.53200 1.000 8.21000  ? 120 THR B CG2 1 
ATOM   3070 N N   . HIS B 1 121 ? 13.38200 -13.91300 185.19300 1.000 7.57000  ? 121 HIS B N   1 
ATOM   3071 C CA  . HIS B 1 121 ? 13.10300 -13.05900 184.04700 1.000 8.21000  ? 121 HIS B CA  1 
ATOM   3072 C C   . HIS B 1 121 ? 11.61300 -13.00600 183.72600 1.000 8.49000  ? 121 HIS B C   1 
ATOM   3073 O O   . HIS B 1 121 ? 11.22600 -12.55000 182.64500 1.000 7.78000  ? 121 HIS B O   1 
ATOM   3074 C CB  . HIS B 1 121 ? 13.91400 -13.53700 182.84800 1.000 8.10000  ? 121 HIS B CB  1 
ATOM   3075 C CG  . HIS B 1 121 ? 15.37700 -13.24200 182.96600 1.000 6.81000  ? 121 HIS B CG  1 
ATOM   3076 N ND1 . HIS B 1 121 ? 16.16700 -13.77700 183.96400 1.000 7.59000  ? 121 HIS B ND1 1 
ATOM   3077 C CD2 . HIS B 1 121 ? 16.18900 -12.45200 182.22500 1.000 7.41000  ? 121 HIS B CD2 1 
ATOM   3078 C CE1 . HIS B 1 121 ? 17.40600 -13.33600 183.82400 1.000 7.74000  ? 121 HIS B CE1 1 
ATOM   3079 N NE2 . HIS B 1 121 ? 17.44600 -12.52900 182.77500 1.000 7.49000  ? 121 HIS B NE2 1 
ATOM   3080 N N   . HIS B 1 122 ? 10.77400 -13.42800 184.67700 1.000 6.73000  ? 122 HIS B N   1 
ATOM   3081 C CA  . HIS B 1 122 ? 9.33200  -13.51600 184.45400 1.000 7.37000  ? 122 HIS B CA  1 
ATOM   3082 C C   . HIS B 1 122 ? 8.72400  -12.16500 184.08500 1.000 7.86000  ? 122 HIS B C   1 
ATOM   3083 O O   . HIS B 1 122 ? 7.94500  -12.06400 183.12600 1.000 7.83000  ? 122 HIS B O   1 
ATOM   3084 C CB  . HIS B 1 122 ? 8.67700  -14.08600 185.71700 1.000 7.68000  ? 122 HIS B CB  1 
ATOM   3085 C CG  . HIS B 1 122 ? 7.19100  -14.21800 185.63100 1.000 10.27000 ? 122 HIS B CG  1 
ATOM   3086 N ND1 . HIS B 1 122 ? 6.57300  -15.19700 184.88800 1.000 13.56000 ? 122 HIS B ND1 1 
ATOM   3087 C CD2 . HIS B 1 122 ? 6.20100  -13.51400 186.22700 1.000 12.38000 ? 122 HIS B CD2 1 
ATOM   3088 C CE1 . HIS B 1 122 ? 5.26300  -15.07800 185.01100 1.000 13.15000 ? 122 HIS B CE1 1 
ATOM   3089 N NE2 . HIS B 1 122 ? 5.01200  -14.06400 185.81800 1.000 11.56000 ? 122 HIS B NE2 1 
ATOM   3090 N N   . ALA B 1 123 ? 9.04900  -11.11500 184.84700 1.000 7.76000  ? 123 ALA B N   1 
ATOM   3091 C CA  . ALA B 1 123 ? 8.45200  -9.80700  184.58300 1.000 9.25000  ? 123 ALA B CA  1 
ATOM   3092 C C   . ALA B 1 123 ? 8.81600  -9.31600  183.19000 1.000 9.09000  ? 123 ALA B C   1 
ATOM   3093 O O   . ALA B 1 123 ? 7.94300  -8.88800  182.42500 1.000 9.57000  ? 123 ALA B O   1 
ATOM   3094 C CB  . ALA B 1 123 ? 8.88000  -8.78800  185.64500 1.000 9.52000  ? 123 ALA B CB  1 
ATOM   3095 N N   . LEU B 1 124 ? 10.10800 -9.38600  182.84100 1.000 6.75000  ? 124 LEU B N   1 
ATOM   3096 C CA  . LEU B 1 124 ? 10.54200 -8.99800  181.49700 1.000 7.07000  ? 124 LEU B CA  1 
ATOM   3097 C C   . LEU B 1 124 ? 9.80400  -9.78400  180.41800 1.000 9.02000  ? 124 LEU B C   1 
ATOM   3098 O O   . LEU B 1 124 ? 9.38600  -9.21200  179.40500 1.000 7.32000  ? 124 LEU B O   1 
ATOM   3099 C CB  . LEU B 1 124 ? 12.05600 -9.18400  181.35900 1.000 6.83000  ? 124 LEU B CB  1 
ATOM   3100 C CG  . LEU B 1 124 ? 12.68000 -8.88500  179.99200 1.000 7.01000  ? 124 LEU B CG  1 
ATOM   3101 C CD1 . LEU B 1 124 ? 12.44800 -7.42700  179.59200 1.000 8.21000  ? 124 LEU B CD1 1 
ATOM   3102 C CD2 . LEU B 1 124 ? 14.17700 -9.20000  180.04000 1.000 7.45000  ? 124 LEU B CD2 1 
ATOM   3103 N N   . CYS B 1 125 ? 9.62200  -11.09600 180.61400 1.000 6.69000  ? 125 CYS B N   1 
ATOM   3104 C CA  . CYS B 1 125 ? 8.93500  -11.88600 179.59800 1.000 5.89000  ? 125 CYS B CA  1 
ATOM   3105 C C   . CYS B 1 125 ? 7.49400  -11.41400 179.40800 1.000 6.44000  ? 125 CYS B C   1 
ATOM   3106 O O   . CYS B 1 125 ? 7.00300  -11.35300 178.27300 1.000 7.04000  ? 125 CYS B O   1 
ATOM   3107 C CB  . CYS B 1 125 ? 8.94100  -13.36800 179.95400 1.000 7.08000  ? 125 CYS B CB  1 
ATOM   3108 S SG  . CYS B 1 125 ? 10.52000 -14.19700 179.67400 1.000 9.49000  ? 125 CYS B SG  1 
ATOM   3109 N N   . THR B 1 126 ? 6.77500  -11.12200 180.50400 1.000 8.26000  ? 126 THR B N   1 
ATOM   3110 C CA  . THR B 1 126 ? 5.41200  -10.61600 180.33500 1.000 8.55000  ? 126 THR B CA  1 
ATOM   3111 C C   . THR B 1 126 ? 5.42300  -9.28900  179.60000 1.000 10.47000 ? 126 THR B C   1 
ATOM   3112 O O   . THR B 1 126 ? 4.52000  -9.01700  178.80500 1.000 10.31000 ? 126 THR B O   1 
ATOM   3113 C CB  . THR B 1 126 ? 4.68200  -10.45300 181.67600 1.000 8.43000  ? 126 THR B CB  1 
ATOM   3114 O OG1 . THR B 1 126 ? 5.25900  -9.37900  182.43900 1.000 9.94000  ? 126 THR B OG1 1 
ATOM   3115 C CG2 . THR B 1 126 ? 4.69500  -11.74100 182.48300 1.000 8.22000  ? 126 THR B CG2 1 
ATOM   3116 N N   . GLU B 1 127 ? 6.44600  -8.46600  179.83400 1.000 8.97000  ? 127 GLU B N   1 
ATOM   3117 C CA  . GLU B 1 127 ? 6.51400  -7.16900  179.17200 1.000 8.71000  ? 127 GLU B CA  1 
ATOM   3118 C C   . GLU B 1 127 ? 6.76600  -7.31900  177.67500 1.000 8.53000  ? 127 GLU B C   1 
ATOM   3119 O O   . GLU B 1 127 ? 6.11700  -6.65000  176.86400 1.000 9.24000  ? 127 GLU B O   1 
ATOM   3120 C CB  . GLU B 1 127 ? 7.59800  -6.31100  179.80800 1.000 9.43000  ? 127 GLU B CB  1 
ATOM   3121 C CG  . GLU B 1 127 ? 7.53200  -4.86000  179.37900 1.000 12.94000 ? 127 GLU B CG  1 
ATOM   3122 C CD  . GLU B 1 127 ? 6.49200  -4.06700  180.16400 1.000 18.58000 ? 127 GLU B CD  1 
ATOM   3123 O OE1 . GLU B 1 127 ? 6.22500  -2.90800  179.78800 1.000 16.31000 ? 127 GLU B OE1 1 
ATOM   3124 O OE2 . GLU B 1 127 ? 5.94500  -4.59700  181.16100 1.000 18.57000 ? 127 GLU B OE2 1 
ATOM   3125 N N   . ILE B 1 128 ? 7.73200  -8.16100  177.28900 1.000 6.27000  ? 128 ILE B N   1 
ATOM   3126 C CA  . ILE B 1 128 ? 8.01700  -8.34000  175.86700 1.000 6.13000  ? 128 ILE B CA  1 
ATOM   3127 C C   . ILE B 1 128 ? 6.79500  -8.89600  175.14800 1.000 7.48000  ? 128 ILE B C   1 
ATOM   3128 O O   . ILE B 1 128 ? 6.42800  -8.42800  174.06300 1.000 8.68000  ? 128 ILE B O   1 
ATOM   3129 C CB  . ILE B 1 128 ? 9.24500  -9.24200  175.66000 1.000 5.92000  ? 128 ILE B CB  1 
ATOM   3130 C CG1 . ILE B 1 128 ? 10.49400 -8.60200  176.26500 1.000 6.71000  ? 128 ILE B CG1 1 
ATOM   3131 C CG2 . ILE B 1 128 ? 9.45400  -9.53700  174.15500 1.000 8.39000  ? 128 ILE B CG2 1 
ATOM   3132 C CD1 . ILE B 1 128 ? 11.68700 -9.57200  176.36600 1.000 7.69000  ? 128 ILE B CD1 1 
ATOM   3133 N N   . ALA B 1 129 ? 6.14500  -9.90300  175.73900 1.000 6.96000  ? 129 ALA B N   1 
ATOM   3134 C CA  . ALA B 1 129 ? 4.97100  -10.48800 175.09400 1.000 8.18000  ? 129 ALA B CA  1 
ATOM   3135 C C   . ALA B 1 129 ? 3.85500  -9.46100  174.95900 1.000 7.50000  ? 129 ALA B C   1 
ATOM   3136 O O   . ALA B 1 129 ? 3.22400  -9.35200  173.90300 1.000 8.69000  ? 129 ALA B O   1 
ATOM   3137 C CB  . ALA B 1 129 ? 4.48500  -11.71200 175.87600 1.000 8.12000  ? 129 ALA B CB  1 
ATOM   3138 N N   . ALA B 1 130 ? 3.61400  -8.68300  176.01200 1.000 6.56000  ? 130 ALA B N   1 
ATOM   3139 C CA  . ALA B 1 130 ? 2.54700  -7.68800  175.96200 1.000 8.11000  ? 130 ALA B CA  1 
ATOM   3140 C C   . ALA B 1 130 ? 2.84400  -6.60800  174.92900 1.000 10.82000 ? 130 ALA B C   1 
ATOM   3141 O O   . ALA B 1 130 ? 1.97300  -6.24600  174.12900 1.000 10.30000 ? 130 ALA B O   1 
ATOM   3142 C CB  . ALA B 1 130 ? 2.34100  -7.07100  177.33800 1.000 11.51000 ? 130 ALA B CB  1 
ATOM   3143 N N   . LEU B 1 131 ? 4.07200  -6.08400  174.92500 1.000 8.25000  ? 131 LEU B N   1 
ATOM   3144 C CA  . LEU B 1 131 ? 4.38500  -4.97600  174.02200 1.000 8.54000  ? 131 LEU B CA  1 
ATOM   3145 C C   . LEU B 1 131 ? 4.49700  -5.43500  172.57200 1.000 10.48000 ? 131 LEU B C   1 
ATOM   3146 O O   . LEU B 1 131 ? 4.20100  -4.65900  171.65600 1.000 12.29000 ? 131 LEU B O   1 
ATOM   3147 C CB  . LEU B 1 131 ? 5.67400  -4.28400  174.46200 1.000 7.87000  ? 131 LEU B CB  1 
ATOM   3148 C CG  . LEU B 1 131 ? 5.60600  -3.59100  175.83100 1.000 10.97000 ? 131 LEU B CG  1 
ATOM   3149 C CD1 . LEU B 1 131 ? 6.92800  -2.90000  176.15800 1.000 9.77000  ? 131 LEU B CD1 1 
ATOM   3150 C CD2 . LEU B 1 131 ? 4.45000  -2.60200  175.87200 1.000 12.15000 ? 131 LEU B CD2 1 
ATOM   3151 N N   . MET B 1 132 ? 4.93000  -6.67500  172.33200 1.000 9.02000  ? 132 MET B N   1 
ATOM   3152 C CA  . MET B 1 132 ? 4.95200  -7.18700  170.96700 1.000 7.50000  ? 132 MET B CA  1 
ATOM   3153 C C   . MET B 1 132 ? 3.59600  -7.70400  170.51200 1.000 10.31000 ? 132 MET B C   1 
ATOM   3154 O O   . MET B 1 132 ? 3.38200  -7.85800  169.30500 1.000 10.04000 ? 132 MET B O   1 
ATOM   3155 C CB  . MET B 1 132 ? 5.96900  -8.32600  170.81800 1.000 8.79000  ? 132 MET B CB  1 
ATOM   3156 C CG  . MET B 1 132 ? 7.43000  -7.91300  170.94400 1.000 9.38000  ? 132 MET B CG  1 
ATOM   3157 S SD  . MET B 1 132 ? 7.91500  -6.73300  169.66400 1.000 9.20000  ? 132 MET B SD  1 
ATOM   3158 C CE  . MET B 1 132 ? 7.62800  -7.66500  168.16200 1.000 9.50000  ? 132 MET B CE  1 
ATOM   3159 N N   . ASP B 1 133 ? 2.68800  -7.98900  171.44200 1.000 9.79000  ? 133 ASP B N   1 
ATOM   3160 C CA  . ASP B 1 133 ? 1.44200  -8.69100  171.12700 1.000 11.24000 ? 133 ASP B CA  1 
ATOM   3161 C C   . ASP B 1 133 ? 1.72700  -9.98500  170.35800 1.000 11.49000 ? 133 ASP B C   1 
ATOM   3162 O O   . ASP B 1 133 ? 1.16200  -10.25600 169.29400 1.000 11.62000 ? 133 ASP B O   1 
ATOM   3163 C CB  . ASP B 1 133 ? 0.47800  -7.77900  170.35700 1.000 12.99000 ? 133 ASP B CB  1 
ATOM   3164 C CG  . ASP B 1 133 ? -0.88600 -8.41600  170.15000 1.000 21.57000 ? 133 ASP B CG  1 
ATOM   3165 O OD1 . ASP B 1 133 ? -1.22800 -9.34500  170.91400 1.000 18.45000 ? 133 ASP B OD1 1 
ATOM   3166 O OD2 . ASP B 1 133 ? -1.60600 -8.00400  169.21100 1.000 21.87000 ? 133 ASP B OD2 1 
ATOM   3167 N N   . LEU B 1 134 ? 2.63300  -10.78900 170.91000 1.000 7.18000  ? 134 LEU B N   1 
ATOM   3168 C CA  . LEU B 1 134 ? 3.04100  -12.06100 170.34000 1.000 8.41000  ? 134 LEU B CA  1 
ATOM   3169 C C   . LEU B 1 134 ? 3.19400  -13.07700 171.46100 1.000 8.71000  ? 134 LEU B C   1 
ATOM   3170 O O   . LEU B 1 134 ? 3.46800  -12.69600 172.60600 1.000 9.98000  ? 134 LEU B O   1 
ATOM   3171 C CB  . LEU B 1 134 ? 4.37700  -11.93600 169.58900 1.000 11.61000 ? 134 LEU B CB  1 
ATOM   3172 C CG  . LEU B 1 134 ? 4.34400  -11.21700 168.24200 1.000 9.49000  ? 134 LEU B CG  1 
ATOM   3173 C CD1 . LEU B 1 134 ? 5.77500  -11.04500 167.73300 1.000 10.95000 ? 134 LEU B CD1 1 
ATOM   3174 C CD2 . LEU B 1 134 ? 3.49400  -12.02000 167.25900 1.000 9.98000  ? 134 LEU B CD2 1 
ATOM   3175 N N   . PRO B 1 135 ? 3.03700  -14.37100 171.16300 1.000 7.59000  ? 135 PRO B N   1 
ATOM   3176 C CA  . PRO B 1 135 ? 3.32500  -15.39600 172.16700 1.000 7.28000  ? 135 PRO B CA  1 
ATOM   3177 C C   . PRO B 1 135 ? 4.82300  -15.52700 172.35800 1.000 9.63000  ? 135 PRO B C   1 
ATOM   3178 O O   . PRO B 1 135 ? 5.60500  -15.35600 171.42100 1.000 8.06000  ? 135 PRO B O   1 
ATOM   3179 C CB  . PRO B 1 135 ? 2.73500  -16.66900 171.55200 1.000 8.35000  ? 135 PRO B CB  1 
ATOM   3180 C CG  . PRO B 1 135 ? 2.91700  -16.45400 170.06000 1.000 11.50000 ? 135 PRO B CG  1 
ATOM   3181 C CD  . PRO B 1 135 ? 2.68000  -14.96600 169.85900 1.000 10.64000 ? 135 PRO B CD  1 
ATOM   3182 N N   . LEU B 1 136 ? 5.21700  -15.85900 173.58500 1.000 8.38000  ? 136 LEU B N   1 
ATOM   3183 C CA  . LEU B 1 136 ? 6.62600  -15.93100 173.94700 1.000 6.04000  ? 136 LEU B CA  1 
ATOM   3184 C C   . LEU B 1 136 ? 6.82900  -17.17900 174.78900 1.000 6.68000  ? 136 LEU B C   1 
ATOM   3185 O O   . LEU B 1 136 ? 6.07000  -17.42100 175.73100 1.000 7.60000  ? 136 LEU B O   1 
ATOM   3186 C CB  . LEU B 1 136 ? 7.05100  -14.67400 174.71900 1.000 4.94000  ? 136 LEU B CB  1 
ATOM   3187 C CG  . LEU B 1 136 ? 8.49600  -14.53400 175.22200 1.000 6.94000  ? 136 LEU B CG  1 
ATOM   3188 C CD1 . LEU B 1 136 ? 8.84800  -13.05000 175.40600 1.000 5.71000  ? 136 LEU B CD1 1 
ATOM   3189 C CD2 . LEU B 1 136 ? 8.71800  -15.24900 176.55600 1.000 6.99000  ? 136 LEU B CD2 1 
ATOM   3190 N N   . VAL B 1 137 ? 7.84400  -17.97100 174.46100 1.000 6.06000  ? 137 VAL B N   1 
ATOM   3191 C CA  . VAL B 1 137 ? 8.15100  -19.17400 175.23100 1.000 5.50000  ? 137 VAL B CA  1 
ATOM   3192 C C   . VAL B 1 137 ? 9.54100  -19.00400 175.82500 1.000 5.43000  ? 137 VAL B C   1 
ATOM   3193 O O   . VAL B 1 137 ? 10.51900 -18.85500 175.08200 1.000 7.54000  ? 137 VAL B O   1 
ATOM   3194 C CB  . VAL B 1 137 ? 8.07700  -20.44000 174.36700 1.000 7.98000  ? 137 VAL B CB  1 
ATOM   3195 C CG1 . VAL B 1 137 ? 8.34700  -21.68400 175.21700 1.000 6.26000  ? 137 VAL B CG1 1 
ATOM   3196 C CG2 . VAL B 1 137 ? 6.70900  -20.52900 173.67900 1.000 8.86000  ? 137 VAL B CG2 1 
ATOM   3197 N N   . ALA B 1 138 ? 9.62300  -19.01700 177.15600 1.000 6.94000  ? 138 ALA B N   1 
ATOM   3198 C CA  . ALA B 1 138 ? 10.89100 -18.94000 177.86700 1.000 6.59000  ? 138 ALA B CA  1 
ATOM   3199 C C   . ALA B 1 138 ? 11.39600 -20.34600 178.17200 1.000 8.01000  ? 138 ALA B C   1 
ATOM   3200 O O   . ALA B 1 138 ? 10.60800 -21.26900 178.41000 1.000 6.98000  ? 138 ALA B O   1 
ATOM   3201 C CB  . ALA B 1 138 ? 10.73200 -18.12900 179.15500 1.000 6.74000  ? 138 ALA B CB  1 
ATOM   3202 N N   . VAL B 1 139 ? 12.71900 -20.50700 178.15800 1.000 6.66000  ? 139 VAL B N   1 
ATOM   3203 C CA  . VAL B 1 139 ? 13.35700 -21.82200 178.21200 1.000 6.78000  ? 139 VAL B CA  1 
ATOM   3204 C C   . VAL B 1 139 ? 14.16800 -21.94900 179.49900 1.000 8.12000  ? 139 VAL B C   1 
ATOM   3205 O O   . VAL B 1 139 ? 15.03900 -21.11400 179.77500 1.000 7.57000  ? 139 VAL B O   1 
ATOM   3206 C CB  . VAL B 1 139 ? 14.25800 -22.05400 176.98300 1.000 6.43000  ? 139 VAL B CB  1 
ATOM   3207 C CG1 . VAL B 1 139 ? 14.89900 -23.44900 177.04200 1.000 8.64000  ? 139 VAL B CG1 1 
ATOM   3208 C CG2 . VAL B 1 139 ? 13.45500 -21.85700 175.68700 1.000 6.94000  ? 139 VAL B CG2 1 
ATOM   3209 N N   . HIS B 1 140 ? 13.89700 -23.00500 180.27100 1.000 6.45000  ? 140 HIS B N   1 
ATOM   3210 C CA  . HIS B 1 140 ? 14.65500 -23.30000 181.49200 1.000 8.57000  ? 140 HIS B CA  1 
ATOM   3211 C C   . HIS B 1 140 ? 15.76300 -24.30000 181.16000 1.000 10.61000 ? 140 HIS B C   1 
ATOM   3212 O O   . HIS B 1 140 ? 15.70600 -25.48300 181.50100 1.000 11.84000 ? 140 HIS B O   1 
ATOM   3213 C CB  . HIS B 1 140 ? 13.72000 -23.83500 182.57500 1.000 8.97000  ? 140 HIS B CB  1 
ATOM   3214 C CG  . HIS B 1 140 ? 14.33400 -23.90100 183.94100 1.000 13.40000 ? 140 HIS B CG  1 
ATOM   3215 N ND1 . HIS B 1 140 ? 15.53000 -23.29400 184.25500 1.000 10.51000 ? 140 HIS B ND1 1 
ATOM   3216 C CD2 . HIS B 1 140 ? 13.90300 -24.49200 185.08100 1.000 23.57000 ? 140 HIS B CD2 1 
ATOM   3217 C CE1 . HIS B 1 140 ? 15.81800 -23.51700 185.52500 1.000 15.50000 ? 140 HIS B CE1 1 
ATOM   3218 N NE2 . HIS B 1 140 ? 14.84400 -24.23900 186.05200 1.000 19.25000 ? 140 HIS B NE2 1 
ATOM   3219 N N   . TYR B 1 141 ? 16.78700 -23.80100 180.47400 1.000 7.52000  ? 141 TYR B N   1 
ATOM   3220 C CA  . TYR B 1 141 ? 17.85600 -24.66700 179.98900 1.000 7.38000  ? 141 TYR B CA  1 
ATOM   3221 C C   . TYR B 1 141 ? 18.75800 -25.16100 181.13400 1.000 7.69000  ? 141 TYR B C   1 
ATOM   3222 O O   . TYR B 1 141 ? 18.82900 -24.57300 182.21600 1.000 8.06000  ? 141 TYR B O   1 
ATOM   3223 C CB  . TYR B 1 141 ? 18.67900 -23.93200 178.93200 1.000 6.06000  ? 141 TYR B CB  1 
ATOM   3224 C CG  . TYR B 1 141 ? 19.20600 -22.58000 179.38700 1.000 6.29000  ? 141 TYR B CG  1 
ATOM   3225 C CD1 . TYR B 1 141 ? 20.31700 -22.49300 180.22600 1.000 6.24000  ? 141 TYR B CD1 1 
ATOM   3226 C CD2 . TYR B 1 141 ? 18.59400 -21.39500 178.98000 1.000 6.18000  ? 141 TYR B CD2 1 
ATOM   3227 C CE1 . TYR B 1 141 ? 20.80600 -21.26300 180.64400 1.000 8.12000  ? 141 TYR B CE1 1 
ATOM   3228 C CE2 . TYR B 1 141 ? 19.08300 -20.14700 179.38900 1.000 5.41000  ? 141 TYR B CE2 1 
ATOM   3229 C CZ  . TYR B 1 141 ? 20.19100 -20.09400 180.21700 1.000 7.89000  ? 141 TYR B CZ  1 
ATOM   3230 O OH  . TYR B 1 141 ? 20.69100 -18.87900 180.63600 1.000 6.46000  ? 141 TYR B OH  1 
ATOM   3231 N N   . ALA B 1 142 ? 19.46500 -26.26600 180.86900 1.000 7.93000  ? 142 ALA B N   1 
ATOM   3232 C CA  . ALA B 1 142 ? 20.37500 -26.85100 181.85300 1.000 9.50000  ? 142 ALA B CA  1 
ATOM   3233 C C   . ALA B 1 142 ? 21.52300 -25.89600 182.18100 1.000 8.94000  ? 142 ALA B C   1 
ATOM   3234 O O   . ALA B 1 142 ? 22.15200 -25.32900 181.28100 1.000 8.70000  ? 142 ALA B O   1 
ATOM   3235 C CB  . ALA B 1 142 ? 20.93100 -28.17700 181.32200 1.000 12.19000 ? 142 ALA B CB  1 
ATOM   3236 N N   . ARG B 1 143 ? 21.80800 -25.73400 183.47600 1.000 6.80000  ? 143 ARG B N   1 
ATOM   3237 C CA  . ARG B 1 143 ? 22.76500 -24.74500 183.96100 1.000 5.87000  ? 143 ARG B CA  1 
ATOM   3238 C C   . ARG B 1 143 ? 24.03700 -25.39600 184.48800 1.000 7.36000  ? 143 ARG B C   1 
ATOM   3239 O O   . ARG B 1 143 ? 24.01500 -26.51900 185.00100 1.000 7.76000  ? 143 ARG B O   1 
ATOM   3240 C CB  . ARG B 1 143 ? 22.15200 -23.89400 185.08000 1.000 5.31000  ? 143 ARG B CB  1 
ATOM   3241 C CG  . ARG B 1 143 ? 20.99900 -23.02200 184.60200 1.000 7.21000  ? 143 ARG B CG  1 
ATOM   3242 C CD  . ARG B 1 143 ? 20.28300 -22.33600 185.76500 1.000 8.07000  ? 143 ARG B CD  1 
ATOM   3243 N NE  . ARG B 1 143 ? 19.74000 -23.30500 186.71400 1.000 9.69000  ? 143 ARG B NE  1 
ATOM   3244 C CZ  . ARG B 1 143 ? 19.01000 -22.97600 187.77200 1.000 10.57000 ? 143 ARG B CZ  1 
ATOM   3245 N NH1 . ARG B 1 143 ? 18.56500 -23.91900 188.59900 1.000 9.79000  ? 143 ARG B NH1 1 
ATOM   3246 N NH2 . ARG B 1 143 ? 18.70700 -21.70300 187.99500 1.000 8.31000  ? 143 ARG B NH2 1 
ATOM   3247 N N   . ALA B 1 144 ? 25.14700 -24.66100 184.36500 1.000 7.37000  ? 144 ALA B N   1 
ATOM   3248 C CA  . ALA B 1 144 ? 26.41500 -25.02300 184.98600 1.000 7.15000  ? 144 ALA B CA  1 
ATOM   3249 C C   . ALA B 1 144 ? 26.41400 -24.61500 186.45700 1.000 8.77000  ? 144 ALA B C   1 
ATOM   3250 O O   . ALA B 1 144 ? 25.63100 -23.76000 186.87300 1.000 7.08000  ? 144 ALA B O   1 
ATOM   3251 C CB  . ALA B 1 144 ? 27.56400 -24.33700 184.24500 1.000 6.15000  ? 144 ALA B CB  1 
ATOM   3252 N N   . PRO B 1 145 ? 27.30600 -25.19200 187.28000 1.000 7.09000  ? 145 PRO B N   1 
ATOM   3253 C CA  . PRO B 1 145 ? 28.35500 -26.16700 186.97800 1.000 8.20000  ? 145 PRO B CA  1 
ATOM   3254 C C   . PRO B 1 145 ? 27.83500 -27.59700 186.88000 1.000 7.79000  ? 145 PRO B C   1 
ATOM   3255 O O   . PRO B 1 145 ? 28.58900 -28.47400 186.47200 1.000 8.34000  ? 145 PRO B O   1 
ATOM   3256 C CB  . PRO B 1 145 ? 29.31400 -26.01800 188.16600 1.000 7.51000  ? 145 PRO B CB  1 
ATOM   3257 C CG  . PRO B 1 145 ? 28.42300 -25.64400 189.29600 1.000 8.56000  ? 145 PRO B CG  1 
ATOM   3258 C CD  . PRO B 1 145 ? 27.35200 -24.75400 188.68700 1.000 7.48000  ? 145 PRO B CD  1 
ATOM   3259 N N   . GLU B 1 146 ? 26.57000 -27.82800 187.24300 1.000 8.01000  ? 146 GLU B N   1 
ATOM   3260 C CA  . GLU B 1 146 ? 26.05300 -29.19300 187.20700 1.000 8.86000  ? 146 GLU B CA  1 
ATOM   3261 C C   . GLU B 1 146 ? 26.09100 -29.75100 185.79400 1.000 11.28000 ? 146 GLU B C   1 
ATOM   3262 O O   . GLU B 1 146 ? 26.44200 -30.92000 185.58500 1.000 9.19000  ? 146 GLU B O   1 
ATOM   3263 C CB  . GLU B 1 146 ? 24.63400 -29.23500 187.77200 1.000 9.90000  ? 146 GLU B CB  1 
ATOM   3264 C CG  . GLU B 1 146 ? 24.55100 -28.83000 189.24100 1.000 12.42000 ? 146 GLU B CG  1 
ATOM   3265 C CD  . GLU B 1 146 ? 24.09300 -27.38900 189.43200 1.000 14.47000 ? 146 GLU B CD  1 
ATOM   3266 O OE1 . GLU B 1 146 ? 24.52900 -26.51400 188.65200 1.000 9.81000  ? 146 GLU B OE1 1 
ATOM   3267 O OE2 . GLU B 1 146 ? 23.29000 -27.13200 190.35800 1.000 14.19000 ? 146 GLU B OE2 1 
ATOM   3268 N N   . ALA B 1 147 ? 25.76400 -28.91700 184.81200 1.000 8.36000  ? 147 ALA B N   1 
ATOM   3269 C CA  . ALA B 1 147 ? 25.81800 -29.28000 183.39700 1.000 9.95000  ? 147 ALA B CA  1 
ATOM   3270 C C   . ALA B 1 147 ? 26.74100 -28.29600 182.69200 1.000 9.55000  ? 147 ALA B C   1 
ATOM   3271 O O   . ALA B 1 147 ? 26.32400 -27.16800 182.37500 1.000 8.92000  ? 147 ALA B O   1 
ATOM   3272 C CB  . ALA B 1 147 ? 24.41500 -29.25100 182.79700 1.000 9.72000  ? 147 ALA B CB  1 
ATOM   3273 N N   . PRO B 1 148 ? 27.99700 -28.66100 182.44200 1.000 8.40000  ? 148 PRO B N   1 
ATOM   3274 C CA  . PRO B 1 148 ? 28.93200 -27.72800 181.79500 1.000 9.19000  ? 148 PRO B CA  1 
ATOM   3275 C C   . PRO B 1 148 ? 28.56700 -27.46700 180.33800 1.000 8.59000  ? 148 PRO B C   1 
ATOM   3276 O O   . PRO B 1 148 ? 27.73600 -28.15200 179.72900 1.000 7.06000  ? 148 PRO B O   1 
ATOM   3277 C CB  . PRO B 1 148 ? 30.28600 -28.44300 181.89700 1.000 13.56000 ? 148 PRO B CB  1 
ATOM   3278 C CG  . PRO B 1 148 ? 30.10100 -29.50400 182.97100 1.000 14.49000 ? 148 PRO B CG  1 
ATOM   3279 C CD  . PRO B 1 148 ? 28.65200 -29.91200 182.86100 1.000 9.26000  ? 148 PRO B CD  1 
ATOM   3280 N N   . PHE B 1 149 ? 29.21400 -26.43500 179.78000 1.000 7.64000  ? 149 PHE B N   1 
ATOM   3281 C CA  . PHE B 1 149 ? 29.24500 -26.21900 178.33300 1.000 8.12000  ? 149 PHE B CA  1 
ATOM   3282 C C   . PHE B 1 149 ? 29.37400 -27.55700 177.61500 1.000 9.35000  ? 149 PHE B C   1 
ATOM   3283 O O   . PHE B 1 149 ? 30.22500 -28.36600 178.00200 1.000 11.75000 ? 149 PHE B O   1 
ATOM   3284 C CB  . PHE B 1 149 ? 30.42400 -25.32600 177.93600 1.000 6.60000  ? 149 PHE B CB  1 
ATOM   3285 C CG  . PHE B 1 149 ? 30.63200 -25.23500 176.44700 1.000 8.47000  ? 149 PHE B CG  1 
ATOM   3286 C CD1 . PHE B 1 149 ? 29.86900 -24.36000 175.69000 1.000 8.21000  ? 149 PHE B CD1 1 
ATOM   3287 C CD2 . PHE B 1 149 ? 31.57000 -26.03700 175.80200 1.000 8.72000  ? 149 PHE B CD2 1 
ATOM   3288 C CE1 . PHE B 1 149 ? 30.03400 -24.27300 174.30500 1.000 8.19000  ? 149 PHE B CE1 1 
ATOM   3289 C CE2 . PHE B 1 149 ? 31.74800 -25.95700 174.41900 1.000 10.32000 ? 149 PHE B CE2 1 
ATOM   3290 C CZ  . PHE B 1 149 ? 30.97900 -25.07300 173.67100 1.000 9.29000  ? 149 PHE B CZ  1 
ATOM   3291 N N   . PRO B 1 150 ? 28.58800 -27.82800 176.55300 1.000 8.69000  ? 150 PRO B N   1 
ATOM   3292 C CA  . PRO B 1 150 ? 27.58300 -26.98000 175.90700 1.000 7.69000  ? 150 PRO B CA  1 
ATOM   3293 C C   . PRO B 1 150 ? 26.12400 -27.28200 176.27800 1.000 9.12000  ? 150 PRO B C   1 
ATOM   3294 O O   . PRO B 1 150 ? 25.24000 -27.02400 175.45400 1.000 8.49000  ? 150 PRO B O   1 
ATOM   3295 C CB  . PRO B 1 150 ? 27.80200 -27.28900 174.42400 1.000 11.12000 ? 150 PRO B CB  1 
ATOM   3296 C CG  . PRO B 1 150 ? 28.09700 -28.78400 174.44100 1.000 11.51000 ? 150 PRO B CG  1 
ATOM   3297 C CD  . PRO B 1 150 ? 28.85000 -29.04100 175.75400 1.000 13.17000 ? 150 PRO B CD  1 
ATOM   3298 N N   . ALA B 1 151 ? 25.87200 -27.79600 177.48400 1.000 8.25000  ? 151 ALA B N   1 
ATOM   3299 C CA  . ALA B 1 151 ? 24.53700 -28.28700 177.82000 1.000 6.19000  ? 151 ALA B CA  1 
ATOM   3300 C C   . ALA B 1 151 ? 23.45700 -27.22100 177.63200 1.000 8.77000  ? 151 ALA B C   1 
ATOM   3301 O O   . ALA B 1 151 ? 22.37100 -27.51800 177.11600 1.000 7.91000  ? 151 ALA B O   1 
ATOM   3302 C CB  . ALA B 1 151 ? 24.52500 -28.81500 179.25900 1.000 5.62000  ? 151 ALA B CB  1 
ATOM   3303 N N   . ALA B 1 152 ? 23.71900 -25.98200 178.06500 1.000 8.46000  ? 152 ALA B N   1 
ATOM   3304 C CA  . ALA B 1 152 ? 22.70600 -24.93200 177.95200 1.000 8.00000  ? 152 ALA B CA  1 
ATOM   3305 C C   . ALA B 1 152 ? 22.32100 -24.70400 176.50000 1.000 7.91000  ? 152 ALA B C   1 
ATOM   3306 O O   . ALA B 1 152 ? 21.13500 -24.59900 176.16200 1.000 6.58000  ? 152 ALA B O   1 
ATOM   3307 C CB  . ALA B 1 152 ? 23.22600 -23.63500 178.56500 1.000 7.10000  ? 152 ALA B CB  1 
ATOM   3308 N N   . ILE B 1 153 ? 23.33100 -24.62700 175.63400 1.000 5.98000  ? 153 ILE B N   1 
ATOM   3309 C CA  . ILE B 1 153 ? 23.14000 -24.41300 174.20200 1.000 9.45000  ? 153 ILE B CA  1 
ATOM   3310 C C   . ILE B 1 153 ? 22.29000 -25.52200 173.60000 1.000 10.43000 ? 153 ILE B C   1 
ATOM   3311 O O   . ILE B 1 153 ? 21.38100 -25.27300 172.79200 1.000 9.56000  ? 153 ILE B O   1 
ATOM   3312 C CB  . ILE B 1 153 ? 24.51600 -24.34000 173.50600 1.000 11.40000 ? 153 ILE B CB  1 
ATOM   3313 C CG1 . ILE B 1 153 ? 25.23100 -23.02400 173.80900 1.000 16.16000 ? 153 ILE B CG1 1 
ATOM   3314 C CG2 . ILE B 1 153 ? 24.39900 -24.64600 172.01100 1.000 13.26000 ? 153 ILE B CG2 1 
ATOM   3315 C CD1 . ILE B 1 153 ? 24.30600 -21.81400 173.90700 1.000 12.22000 ? 153 ILE B CD1 1 
ATOM   3316 N N   . LEU B 1 154 ? 22.61000 -26.77500 173.93400 1.000 7.67000  ? 154 LEU B N   1 
ATOM   3317 C CA  . LEU B 1 154 ? 21.88500 -27.88200 173.32100 1.000 10.25000 ? 154 LEU B CA  1 
ATOM   3318 C C   . LEU B 1 154 ? 20.43000 -27.91400 173.78000 1.000 11.36000 ? 154 LEU B C   1 
ATOM   3319 O O   . LEU B 1 154 ? 19.55100 -28.30900 173.00500 1.000 10.17000 ? 154 LEU B O   1 
ATOM   3320 C CB  . LEU B 1 154 ? 22.59300 -29.20600 173.61700 1.000 9.89000  ? 154 LEU B CB  1 
ATOM   3321 C CG  . LEU B 1 154 ? 24.04000 -29.28000 173.11000 1.000 11.09000 ? 154 LEU B CG  1 
ATOM   3322 C CD1 . LEU B 1 154 ? 24.68000 -30.59100 173.51300 1.000 17.41000 ? 154 LEU B CD1 1 
ATOM   3323 C CD2 . LEU B 1 154 ? 24.10400 -29.09200 171.60300 1.000 13.77000 ? 154 LEU B CD2 1 
ATOM   3324 N N   . ASP B 1 155 ? 20.15500 -27.48400 175.01800 1.000 9.06000  ? 155 ASP B N   1 
ATOM   3325 C CA  . ASP B 1 155 ? 18.77500 -27.35800 175.48500 1.000 9.04000  ? 155 ASP B CA  1 
ATOM   3326 C C   . ASP B 1 155 ? 18.04900 -26.22900 174.75600 1.000 9.58000  ? 155 ASP B C   1 
ATOM   3327 O O   . ASP B 1 155 ? 16.89800 -26.38600 174.32400 1.000 9.91000  ? 155 ASP B O   1 
ATOM   3328 C CB  . ASP B 1 155 ? 18.75000 -27.11200 176.99600 1.000 9.02000  ? 155 ASP B CB  1 
ATOM   3329 C CG  . ASP B 1 155 ? 18.69800 -28.40800 177.81000 1.000 11.72000 ? 155 ASP B CG  1 
ATOM   3330 O OD1 . ASP B 1 155 ? 18.80100 -29.50600 177.21300 1.000 11.35000 ? 155 ASP B OD1 1 
ATOM   3331 O OD2 . ASP B 1 155 ? 18.55200 -28.31600 179.05200 1.000 10.59000 ? 155 ASP B OD2 1 
ATOM   3332 N N   . CYS B 1 156 ? 18.69800 -25.07200 174.62800 1.000 7.15000  ? 156 CYS B N   1 
ATOM   3333 C CA  . CYS B 1 156 ? 18.09000 -23.95900 173.89900 1.000 5.72000  ? 156 CYS B CA  1 
ATOM   3334 C C   . CYS B 1 156 ? 17.78000 -24.33100 172.45500 1.000 7.19000  ? 156 CYS B C   1 
ATOM   3335 O O   . CYS B 1 156 ? 16.68600 -24.03500 171.95400 1.000 7.62000  ? 156 CYS B O   1 
ATOM   3336 C CB  . CYS B 1 156 ? 19.01300 -22.74600 173.96300 1.000 6.94000  ? 156 CYS B CB  1 
ATOM   3337 S SG  . CYS B 1 156 ? 19.08600 -21.99700 175.60800 1.000 8.66000  ? 156 CYS B SG  1 
ATOM   3338 N N   . GLU B 1 157 ? 18.71300 -25.01700 171.79100 1.000 6.53000  ? 157 GLU B N   1 
ATOM   3339 C CA  . GLU B 1 157 ? 18.46100 -25.46400 170.42300 1.000 6.39000  ? 157 GLU B CA  1 
ATOM   3340 C C   . GLU B 1 157 ? 17.28400 -26.43600 170.37100 1.000 8.02000  ? 157 GLU B C   1 
ATOM   3341 O O   . GLU B 1 157 ? 16.37900 -26.29300 169.53900 1.000 9.27000  ? 157 GLU B O   1 
ATOM   3342 C CB  . GLU B 1 157 ? 19.70900 -26.12300 169.83000 1.000 6.65000  ? 157 GLU B CB  1 
ATOM   3343 C CG  . GLU B 1 157 ? 19.47900 -26.60900 168.40100 1.000 10.40000 ? 157 GLU B CG  1 
ATOM   3344 C CD  . GLU B 1 157 ? 20.55000 -27.55500 167.87400 1.000 13.05000 ? 157 GLU B CD  1 
ATOM   3345 O OE1 . GLU B 1 157 ? 21.37300 -28.06800 168.67300 1.000 12.93000 ? 157 GLU B OE1 1 
ATOM   3346 O OE2 . GLU B 1 157 ? 20.55900 -27.79300 166.64200 1.000 11.50000 ? 157 GLU B OE2 1 
ATOM   3347 N N   . ALA B 1 158 ? 17.27000 -27.42400 171.26900 1.000 8.18000  ? 158 ALA B N   1 
ATOM   3348 C CA  . ALA B 1 158 ? 16.19900 -28.41700 171.23300 1.000 9.93000  ? 158 ALA B CA  1 
ATOM   3349 C C   . ALA B 1 158 ? 14.84200 -27.76600 171.45100 1.000 10.31000 ? 158 ALA B C   1 
ATOM   3350 O O   . ALA B 1 158 ? 13.87800 -28.06900 170.73500 1.000 8.04000  ? 158 ALA B O   1 
ATOM   3351 C CB  . ALA B 1 158 ? 16.44000 -29.50600 172.27800 1.000 8.48000  ? 158 ALA B CB  1 
ATOM   3352 N N   . ALA B 1 159 ? 14.74800 -26.86600 172.43300 1.000 7.91000  ? 159 ALA B N   1 
ATOM   3353 C CA  . ALA B 1 159 ? 13.48900 -26.17700 172.68700 1.000 7.20000  ? 159 ALA B CA  1 
ATOM   3354 C C   . ALA B 1 159 ? 13.04800 -25.36200 171.47500 1.000 7.54000  ? 159 ALA B C   1 
ATOM   3355 O O   . ALA B 1 159 ? 11.86300 -25.36100 171.11800 1.000 9.24000  ? 159 ALA B O   1 
ATOM   3356 C CB  . ALA B 1 159 ? 13.61600 -25.27300 173.91500 1.000 8.57000  ? 159 ALA B CB  1 
ATOM   3357 N N   . THR B 1 160 ? 13.97900 -24.64200 170.84100 1.000 7.13000  ? 160 THR B N   1 
ATOM   3358 C CA  . THR B 1 160 ? 13.60400 -23.81800 169.69000 1.000 8.88000  ? 160 THR B CA  1 
ATOM   3359 C C   . THR B 1 160 ? 13.10700 -24.67800 168.53100 1.000 7.27000  ? 160 THR B C   1 
ATOM   3360 O O   . THR B 1 160 ? 12.13100 -24.32000 167.85300 1.000 7.58000  ? 160 THR B O   1 
ATOM   3361 C CB  . THR B 1 160 ? 14.78700 -22.95600 169.23700 1.000 6.85000  ? 160 THR B CB  1 
ATOM   3362 O OG1 . THR B 1 160 ? 15.29200 -22.20200 170.34700 1.000 6.48000  ? 160 THR B OG1 1 
ATOM   3363 C CG2 . THR B 1 160 ? 14.35800 -21.98400 168.12700 1.000 8.13000  ? 160 THR B CG2 1 
ATOM   3364 N N   . ARG B 1 161 ? 13.78000 -25.80600 168.27100 1.000 6.66000  ? 161 ARG B N   1 
ATOM   3365 C CA  . ARG B 1 161 ? 13.32100 -26.70300 167.20900 1.000 8.73000  ? 161 ARG B CA  1 
ATOM   3366 C C   . ARG B 1 161 ? 11.92800 -27.23900 167.50900 1.000 8.12000  ? 161 ARG B C   1 
ATOM   3367 O O   . ARG B 1 161 ? 11.09500 -27.37400 166.60400 1.000 9.55000  ? 161 ARG B O   1 
ATOM   3368 C CB  . ARG B 1 161 ? 14.30200 -27.86200 167.03000 1.000 8.42000  ? 161 ARG B CB  1 
ATOM   3369 C CG  . ARG B 1 161 ? 15.62200 -27.46600 166.39500 1.000 10.26000 ? 161 ARG B CG  1 
ATOM   3370 C CD  . ARG B 1 161 ? 16.51100 -28.68000 166.11500 1.000 9.03000  ? 161 ARG B CD  1 
ATOM   3371 N NE  . ARG B 1 161 ? 17.80100 -28.24800 165.58400 1.000 11.66000 ? 161 ARG B NE  1 
ATOM   3372 C CZ  . ARG B 1 161 ? 18.00400 -27.86500 164.32800 1.000 13.75000 ? 161 ARG B CZ  1 
ATOM   3373 N NH1 . ARG B 1 161 ? 19.21200 -27.46700 163.94400 1.000 10.58000 ? 161 ARG B NH1 1 
ATOM   3374 N NH2 . ARG B 1 161 ? 17.00100 -27.87900 163.45400 1.000 11.37000 ? 161 ARG B NH2 1 
ATOM   3375 N N   . TRP B 1 162 ? 11.66000 -27.55200 168.77500 1.000 7.37000  ? 162 TRP B N   1 
ATOM   3376 C CA  . TRP B 1 162 ? 10.35800 -28.08800 169.15200 1.000 10.35000 ? 162 TRP B CA  1 
ATOM   3377 C C   . TRP B 1 162 ? 9.26800  -27.03600 168.98500 1.000 11.22000 ? 162 TRP B C   1 
ATOM   3378 O O   . TRP B 1 162 ? 8.21300  -27.31100 168.39700 1.000 10.26000 ? 162 TRP B O   1 
ATOM   3379 C CB  . TRP B 1 162 ? 10.42300 -28.60300 170.59100 1.000 8.22000  ? 162 TRP B CB  1 
ATOM   3380 C CG  . TRP B 1 162 ? 9.16900  -29.25400 171.10800 1.000 9.26000  ? 162 TRP B CG  1 
ATOM   3381 C CD1 . TRP B 1 162 ? 8.77400  -30.55200 170.91600 1.000 12.50000 ? 162 TRP B CD1 1 
ATOM   3382 C CD2 . TRP B 1 162 ? 8.16000  -28.64500 171.92500 1.000 10.53000 ? 162 TRP B CD2 1 
ATOM   3383 N NE1 . TRP B 1 162 ? 7.58200  -30.78700 171.57000 1.000 12.57000 ? 162 TRP B NE1 1 
ATOM   3384 C CE2 . TRP B 1 162 ? 7.18400  -29.63300 172.19700 1.000 12.70000 ? 162 TRP B CE2 1 
ATOM   3385 C CE3 . TRP B 1 162 ? 7.98700  -27.36000 172.45900 1.000 9.21000  ? 162 TRP B CE3 1 
ATOM   3386 C CZ2 . TRP B 1 162 ? 6.05100  -29.37400 172.97500 1.000 13.43000 ? 162 TRP B CZ2 1 
ATOM   3387 C CZ3 . TRP B 1 162 ? 6.86200  -27.10400 173.23500 1.000 12.08000 ? 162 TRP B CZ3 1 
ATOM   3388 C CH2 . TRP B 1 162 ? 5.90700  -28.11200 173.48600 1.000 12.98000 ? 162 TRP B CH2 1 
ATOM   3389 N N   . ILE B 1 163 ? 9.51600  -25.81800 169.48400 1.000 8.01000  ? 163 ILE B N   1 
ATOM   3390 C CA  . ILE B 1 163 ? 8.57600  -24.71300 169.30000 1.000 8.52000  ? 163 ILE B CA  1 
ATOM   3391 C C   . ILE B 1 163 ? 8.29000  -24.49500 167.81800 1.000 10.02000 ? 163 ILE B C   1 
ATOM   3392 O O   . ILE B 1 163 ? 7.13700  -24.29100 167.41400 1.000 11.83000 ? 163 ILE B O   1 
ATOM   3393 C CB  . ILE B 1 163 ? 9.12600  -23.42600 169.95100 1.000 8.98000  ? 163 ILE B CB  1 
ATOM   3394 C CG1 . ILE B 1 163 ? 9.20300  -23.57300 171.46800 1.000 9.58000  ? 163 ILE B CG1 1 
ATOM   3395 C CG2 . ILE B 1 163 ? 8.24600  -22.22000 169.60200 1.000 9.28000  ? 163 ILE B CG2 1 
ATOM   3396 C CD1 . ILE B 1 163 ? 10.26400 -22.66200 172.10600 1.000 8.50000  ? 163 ILE B CD1 1 
ATOM   3397 N N   . ALA B 1 164 ? 9.33700  -24.53800 166.98900 1.000 7.27000  ? 164 ALA B N   1 
ATOM   3398 C CA  . ALA B 1 164 ? 9.20300  -24.29600 165.55800 1.000 9.75000  ? 164 ALA B CA  1 
ATOM   3399 C C   . ALA B 1 164 ? 8.35400  -25.35300 164.86200 1.000 12.98000 ? 164 ALA B C   1 
ATOM   3400 O O   . ALA B 1 164 ? 7.88100  -25.10900 163.74700 1.000 13.12000 ? 164 ALA B O   1 
ATOM   3401 C CB  . ALA B 1 164 ? 10.59000 -24.23800 164.90600 1.000 9.66000  ? 164 ALA B CB  1 
ATOM   3402 N N   . SER B 1 165 ? 8.16600  -26.52100 165.48000 1.000 11.24000 ? 165 SER B N   1 
ATOM   3403 C CA  . SER B 1 165 ? 7.39800  -27.60300 164.87500 1.000 12.96000 ? 165 SER B CA  1 
ATOM   3404 C C   . SER B 1 165 ? 5.89600  -27.45400 165.09400 1.000 16.63000 ? 165 SER B C   1 
ATOM   3405 O O   . SER B 1 165 ? 5.13800  -28.33500 164.66100 1.000 16.36000 ? 165 SER B O   1 
ATOM   3406 C CB  . SER B 1 165 ? 7.86400  -28.95800 165.43000 1.000 11.79000 ? 165 SER B CB  1 
ATOM   3407 O OG  . SER B 1 165 ? 7.40400  -29.13100 166.76200 1.000 12.77000 ? 165 SER B OG  1 
ATOM   3408 N N   . SER B 1 166 ? 5.46000  -26.37000 165.73300 1.000 12.99000 ? 166 SER B N   1 
ATOM   3409 C CA  . SER B 1 166 ? 4.06300  -26.14500 166.07700 1.000 15.26000 ? 166 SER B CA  1 
ATOM   3410 C C   . SER B 1 166 ? 3.44400  -27.35300 166.78900 1.000 17.55000 ? 166 SER B C   1 
ATOM   3411 O O   . SER B 1 166 ? 2.48100  -27.94600 166.29900 1.000 15.44000 ? 166 SER B O   1 
ATOM   3412 C CB  . SER B 1 166 ? 3.24600  -25.77400 164.84300 1.000 16.11000 ? 166 SER B CB  1 
ATOM   3413 O OG  . SER B 1 166 ? 3.75800  -24.60100 164.22600 1.000 14.92000 ? 166 SER B OG  1 
ATOM   3414 N N   . PRO B 1 167 ? 3.97300  -27.72400 167.95300 1.000 15.82000 ? 167 PRO B N   1 
ATOM   3415 C CA  . PRO B 1 167 ? 3.44600  -28.89300 168.66200 1.000 14.43000 ? 167 PRO B CA  1 
ATOM   3416 C C   . PRO B 1 167 ? 2.07300  -28.61700 169.25600 1.000 15.68000 ? 167 PRO B C   1 
ATOM   3417 O O   . PRO B 1 167 ? 1.73900  -27.48600 169.62300 1.000 15.30000 ? 167 PRO B O   1 
ATOM   3418 C CB  . PRO B 1 167 ? 4.48900  -29.13400 169.75900 1.000 16.75000 ? 167 PRO B CB  1 
ATOM   3419 C CG  . PRO B 1 167 ? 5.06900  -27.77600 170.01900 1.000 13.60000 ? 167 PRO B CG  1 
ATOM   3420 C CD  . PRO B 1 167 ? 5.05000  -27.04700 168.70700 1.000 14.65000 ? 167 PRO B CD  1 
ATOM   3421 N N   . ALA B 1 168 ? 1.26700  -29.68000 169.34800 1.000 17.25000 ? 168 ALA B N   1 
ATOM   3422 C CA  . ALA B 1 168 ? -0.10100 -29.52600 169.83900 1.000 18.71000 ? 168 ALA B CA  1 
ATOM   3423 C C   . ALA B 1 168 ? -0.12300 -28.95900 171.25200 1.000 20.09000 ? 168 ALA B C   1 
ATOM   3424 O O   . ALA B 1 168 ? -1.01300 -28.17500 171.60000 1.000 19.07000 ? 168 ALA B O   1 
ATOM   3425 C CB  . ALA B 1 168 ? -0.83200 -30.86900 169.79400 1.000 25.96000 ? 168 ALA B CB  1 
ATOM   3426 N N   . GLU B 1 169 ? 0.86300  -29.33200 172.07300 1.000 21.89000 ? 169 GLU B N   1 
ATOM   3427 C CA  . GLU B 1 169 ? 0.89400  -28.89300 173.46400 1.000 20.77000 ? 169 GLU B CA  1 
ATOM   3428 C C   . GLU B 1 169 ? 1.00700  -27.37700 173.58700 1.000 21.07000 ? 169 GLU B C   1 
ATOM   3429 O O   . GLU B 1 169 ? 0.52900  -26.79600 174.56900 1.000 21.45000 ? 169 GLU B O   1 
ATOM   3430 C CB  . GLU B 1 169 ? 2.05600  -29.57300 174.19200 1.000 23.03000 ? 169 GLU B CB  1 
ATOM   3431 C CG  . GLU B 1 169 ? 1.88700  -31.07500 174.37400 1.000 30.54000 ? 169 GLU B CG  1 
ATOM   3432 C CD  . GLU B 1 169 ? 2.33600  -31.88300 173.15800 1.000 39.73000 ? 169 GLU B CD  1 
ATOM   3433 O OE1 . GLU B 1 169 ? 2.38600  -33.12900 173.25900 1.000 45.71000 ? 169 GLU B OE1 1 
ATOM   3434 O OE2 . GLU B 1 169 ? 2.63300  -31.28000 172.10100 1.000 31.36000 ? 169 GLU B OE2 1 
ATOM   3435 N N   . LEU B 1 170 ? 1.63800  -26.71800 172.61600 1.000 18.00000 ? 170 LEU B N   1 
ATOM   3436 C CA  . LEU B 1 170 ? 1.74500  -25.26600 172.66300 1.000 15.02000 ? 170 LEU B CA  1 
ATOM   3437 C C   . LEU B 1 170 ? 0.50000  -24.58100 172.12200 1.000 18.35000 ? 170 LEU B C   1 
ATOM   3438 O O   . LEU B 1 170 ? 0.18200  -23.46600 172.54300 1.000 21.14000 ? 170 LEU B O   1 
ATOM   3439 C CB  . LEU B 1 170 ? 2.96700  -24.80600 171.86600 1.000 19.18000 ? 170 LEU B CB  1 
ATOM   3440 C CG  . LEU B 1 170 ? 4.23900  -24.39000 172.59300 1.000 22.73000 ? 170 LEU B CG  1 
ATOM   3441 C CD1 . LEU B 1 170 ? 5.15800  -23.68400 171.59500 1.000 18.04000 ? 170 LEU B CD1 1 
ATOM   3442 C CD2 . LEU B 1 170 ? 3.93600  -23.50200 173.80200 1.000 18.11000 ? 170 LEU B CD2 1 
ATOM   3443 N N   . GLY B 1 171 ? -0.19300 -25.21100 171.17500 1.000 17.82000 ? 171 GLY B N   1 
ATOM   3444 C CA  . GLY B 1 171 ? -1.41000 -24.65300 170.62200 1.000 20.00000 ? 171 GLY B CA  1 
ATOM   3445 C C   . GLY B 1 171 ? -1.21400 -23.53800 169.62200 1.000 23.34000 ? 171 GLY B C   1 
ATOM   3446 O O   . GLY B 1 171 ? -2.18600 -22.85100 169.28800 1.000 24.43000 ? 171 GLY B O   1 
ATOM   3447 N N   . LEU B 1 172 ? 0.00400  -23.33600 169.13100 1.000 18.48000 ? 172 LEU B N   1 
ATOM   3448 C CA  . LEU B 1 172 ? 0.31700  -22.27500 168.18800 1.000 19.16000 ? 172 LEU B CA  1 
ATOM   3449 C C   . LEU B 1 172 ? 0.62800  -22.86200 166.82100 1.000 16.86000 ? 172 LEU B C   1 
ATOM   3450 O O   . LEU B 1 172 ? 1.13000  -23.98100 166.70400 1.000 19.52000 ? 172 LEU B O   1 
ATOM   3451 C CB  . LEU B 1 172 ? 1.52000  -21.45300 168.66900 1.000 18.98000 ? 172 LEU B CB  1 
ATOM   3452 C CG  . LEU B 1 172 ? 1.36700  -20.79300 170.04000 1.000 17.89000 ? 172 LEU B CG  1 
ATOM   3453 C CD1 . LEU B 1 172 ? 2.71800  -20.30600 170.57100 1.000 17.34000 ? 172 LEU B CD1 1 
ATOM   3454 C CD2 . LEU B 1 172 ? 0.37700  -19.65100 169.96000 1.000 18.18000 ? 172 LEU B CD2 1 
ATOM   3455 N N   . THR B 1 173 ? 0.32300  -22.09700 165.78100 1.000 16.81000 ? 173 THR B N   1 
ATOM   3456 C CA  . THR B 1 173 ? 0.82400  -22.38600 164.44500 1.000 14.69000 ? 173 THR B CA  1 
ATOM   3457 C C   . THR B 1 173 ? 1.92500  -21.37300 164.16500 1.000 16.64000 ? 173 THR B C   1 
ATOM   3458 O O   . THR B 1 173 ? 1.64000  -20.19600 163.92100 1.000 15.78000 ? 173 THR B O   1 
ATOM   3459 C CB  . THR B 1 173 ? -0.29100 -22.31600 163.40500 1.000 22.49000 ? 173 THR B CB  1 
ATOM   3460 O OG1 . THR B 1 173 ? -1.35100 -23.20000 163.79600 1.000 23.69000 ? 173 THR B OG1 1 
ATOM   3461 C CG2 . THR B 1 173 ? 0.23200  -22.73400 162.03800 1.000 18.08000 ? 173 THR B CG2 1 
ATOM   3462 N N   . ALA B 1 174 ? 3.17600  -21.82400 164.23200 1.000 13.44000 ? 174 ALA B N   1 
ATOM   3463 C CA  . ALA B 1 174 ? 4.30900  -20.92000 164.10500 1.000 13.94000 ? 174 ALA B CA  1 
ATOM   3464 C C   . ALA B 1 174 ? 4.63000  -20.68300 162.63800 1.000 15.21000 ? 174 ALA B C   1 
ATOM   3465 O O   . ALA B 1 174 ? 4.74000  -21.63500 161.86000 1.000 19.14000 ? 174 ALA B O   1 
ATOM   3466 C CB  . ALA B 1 174 ? 5.53100  -21.49200 164.82500 1.000 13.60000 ? 174 ALA B CB  1 
ATOM   3467 N N   . SER B 1 175 ? 4.76700  -19.41200 162.26100 1.000 12.94000 ? 175 SER B N   1 
ATOM   3468 C CA  . SER B 1 175 ? 5.23500  -19.05700 160.92800 1.000 13.16000 ? 175 SER B CA  1 
ATOM   3469 C C   . SER B 1 175 ? 6.71800  -18.72200 160.89700 1.000 12.86000 ? 175 SER B C   1 
ATOM   3470 O O   . SER B 1 175 ? 7.31200  -18.68600 159.81100 1.000 12.74000 ? 175 SER B O   1 
ATOM   3471 C CB  . SER B 1 175 ? 4.43200  -17.86500 160.38900 1.000 14.33000 ? 175 SER B CB  1 
ATOM   3472 O OG  . SER B 1 175 ? 4.62200  -16.71100 161.19600 1.000 14.23000 ? 175 SER B OG  1 
ATOM   3473 N N   . GLY B 1 176 ? 7.31600  -18.48500 162.05800 1.000 12.80000 ? 176 GLY B N   1 
ATOM   3474 C CA  . GLY B 1 176 ? 8.72700  -18.14700 162.16300 1.000 9.39000  ? 176 GLY B CA  1 
ATOM   3475 C C   . GLY B 1 176 ? 9.06200  -18.00400 163.63100 1.000 8.98000  ? 176 GLY B C   1 
ATOM   3476 O O   . GLY B 1 176 ? 8.17600  -17.89500 164.48200 1.000 9.46000  ? 176 GLY B O   1 
ATOM   3477 N N   . ILE B 1 177 ? 10.36400 -18.00600 163.92000 1.000 7.27000  ? 177 ILE B N   1 
ATOM   3478 C CA  . ILE B 1 177 ? 10.86900 -17.88500 165.28700 1.000 7.44000  ? 177 ILE B CA  1 
ATOM   3479 C C   . ILE B 1 177 ? 11.54500 -16.52900 165.45000 1.000 5.03000  ? 177 ILE B C   1 
ATOM   3480 O O   . ILE B 1 177 ? 12.31400 -16.10000 164.58500 1.000 6.42000  ? 177 ILE B O   1 
ATOM   3481 C CB  . ILE B 1 177 ? 11.85900 -19.01700 165.62600 1.000 8.74000  ? 177 ILE B CB  1 
ATOM   3482 C CG1 . ILE B 1 177 ? 11.17200 -20.38800 165.57900 1.000 9.57000  ? 177 ILE B CG1 1 
ATOM   3483 C CG2 . ILE B 1 177 ? 12.49800 -18.79000 167.00500 1.000 8.76000  ? 177 ILE B CG2 1 
ATOM   3484 C CD1 . ILE B 1 177 ? 10.17200 -20.59300 166.69500 1.000 12.18000 ? 177 ILE B CD1 1 
ATOM   3485 N N   . ILE B 1 178 ? 11.27400 -15.86600 166.57000 1.000 5.40000  ? 178 ILE B N   1 
ATOM   3486 C CA  . ILE B 1 178 ? 12.00600 -14.67400 166.98200 1.000 5.73000  ? 178 ILE B CA  1 
ATOM   3487 C C   . ILE B 1 178 ? 12.84100 -15.08000 168.18800 1.000 5.96000  ? 178 ILE B C   1 
ATOM   3488 O O   . ILE B 1 178 ? 12.28600 -15.38800 169.24500 1.000 7.96000  ? 178 ILE B O   1 
ATOM   3489 C CB  . ILE B 1 178 ? 11.06200 -13.51800 167.32900 1.000 6.85000  ? 178 ILE B CB  1 
ATOM   3490 C CG1 . ILE B 1 178 ? 10.25000 -13.10500 166.10200 1.000 6.85000  ? 178 ILE B CG1 1 
ATOM   3491 C CG2 . ILE B 1 178 ? 11.84100 -12.32700 167.87500 1.000 6.39000  ? 178 ILE B CG2 1 
ATOM   3492 C CD1 . ILE B 1 178 ? 8.99200  -12.33800 166.47000 1.000 10.41000 ? 178 ILE B CD1 1 
ATOM   3493 N N   . THR B 1 179 ? 14.16300 -15.13200 168.04300 1.000 7.35000  ? 179 THR B N   1 
ATOM   3494 C CA  . THR B 1 179 ? 15.00000 -15.43700 169.19900 1.000 6.09000  ? 179 THR B CA  1 
ATOM   3495 C C   . THR B 1 179 ? 15.38700 -14.15600 169.92700 1.000 4.29000  ? 179 THR B C   1 
ATOM   3496 O O   . THR B 1 179 ? 15.58800 -13.10900 169.31400 1.000 6.31000  ? 179 THR B O   1 
ATOM   3497 C CB  . THR B 1 179 ? 16.26600 -16.18600 168.79000 1.000 7.05000  ? 179 THR B CB  1 
ATOM   3498 O OG1 . THR B 1 179 ? 16.92400 -15.46000 167.74200 1.000 4.77000  ? 179 THR B OG1 1 
ATOM   3499 C CG2 . THR B 1 179 ? 15.92200 -17.58400 168.30400 1.000 8.33000  ? 179 THR B CG2 1 
ATOM   3500 N N   . ILE B 1 180 ? 15.49400 -14.24600 171.25100 1.000 4.76000  ? 180 ILE B N   1 
ATOM   3501 C CA  . ILE B 1 180 ? 15.82800 -13.08000 172.06000 1.000 6.02000  ? 180 ILE B CA  1 
ATOM   3502 C C   . ILE B 1 180 ? 16.37000 -13.57200 173.39600 1.000 5.76000  ? 180 ILE B C   1 
ATOM   3503 O O   . ILE B 1 180 ? 15.94100 -14.60600 173.91500 1.000 4.87000  ? 180 ILE B O   1 
ATOM   3504 C CB  . ILE B 1 180 ? 14.58700 -12.16400 172.22700 1.000 5.89000  ? 180 ILE B CB  1 
ATOM   3505 C CG1 . ILE B 1 180 ? 14.92700 -10.88600 172.99700 1.000 7.28000  ? 180 ILE B CG1 1 
ATOM   3506 C CG2 . ILE B 1 180 ? 13.47100 -12.91900 172.91800 1.000 9.02000  ? 180 ILE B CG2 1 
ATOM   3507 C CD1 . ILE B 1 180 ? 13.83400 -9.81100  172.88100 1.000 7.32000  ? 180 ILE B CD1 1 
ATOM   3508 N N   . GLY B 1 181 ? 17.32000 -12.83300 173.95300 1.000 6.32000  ? 181 GLY B N   1 
ATOM   3509 C CA  . GLY B 1 181 ? 17.81700 -13.17900 175.27000 1.000 8.26000  ? 181 GLY B CA  1 
ATOM   3510 C C   . GLY B 1 181 ? 18.87200 -12.18900 175.70500 1.000 6.14000  ? 181 GLY B C   1 
ATOM   3511 O O   . GLY B 1 181 ? 19.47300 -11.49100 174.88000 1.000 8.89000  ? 181 GLY B O   1 
ATOM   3512 N N   . ASP B 1 182 ? 19.08800 -12.14900 177.02300 1.000 6.45000  ? 182 ASP B N   1 
ATOM   3513 C CA  . ASP B 1 182 ? 19.99400 -11.19500 177.65300 1.000 7.69000  ? 182 ASP B CA  1 
ATOM   3514 C C   . ASP B 1 182 ? 21.25100 -11.90000 178.15600 1.000 6.68000  ? 182 ASP B C   1 
ATOM   3515 O O   . ASP B 1 182 ? 21.16600 -12.97500 178.75600 1.000 7.83000  ? 182 ASP B O   1 
ATOM   3516 C CB  . ASP B 1 182 ? 19.29700 -10.46400 178.81400 1.000 8.19000  ? 182 ASP B CB  1 
ATOM   3517 C CG  . ASP B 1 182 ? 18.83800 -11.40500 179.92000 1.000 11.85000 ? 182 ASP B CG  1 
ATOM   3518 O OD1 . ASP B 1 182 ? 18.05600 -12.33700 179.62700 1.000 10.86000 ? 182 ASP B OD1 1 
ATOM   3519 O OD2 . ASP B 1 182 ? 19.25900 -11.20800 181.09000 1.000 12.03000 ? 182 ASP B OD2 1 
ATOM   3520 N N   . SER B 1 183 ? 22.41900 -11.30100 177.89600 1.000 8.16000  ? 183 SER B N   1 
ATOM   3521 C CA  . SER B 1 183 ? 23.70000 -11.73800 178.48000 1.000 7.20000  ? 183 SER B CA  1 
ATOM   3522 C C   . SER B 1 183 ? 24.00800 -13.14300 177.96600 1.000 9.26000  ? 183 SER B C   1 
ATOM   3523 O O   . SER B 1 183 ? 24.15800 -13.31500 176.74500 1.000 9.50000  ? 183 SER B O   1 
ATOM   3524 C CB  . SER B 1 183 ? 23.61200 -11.58600 180.00900 1.000 12.22000 ? 183 SER B CB  1 
ATOM   3525 O OG  . SER B 1 183 ? 24.85100 -11.79300 180.71600 1.000 14.18000 ? 183 SER B OG  1 
ATOM   3526 N N   . ALA B 1 184 ? 24.12700 -14.16000 178.83000 1.000 9.02000  ? 184 ALA B N   1 
ATOM   3527 C CA  . ALA B 1 184 ? 24.28000 -15.53900 178.36600 1.000 7.98000  ? 184 ALA B CA  1 
ATOM   3528 C C   . ALA B 1 184 ? 23.14800 -15.92600 177.43100 1.000 5.91000  ? 184 ALA B C   1 
ATOM   3529 O O   . ALA B 1 184 ? 23.33700 -16.72800 176.50900 1.000 7.19000  ? 184 ALA B O   1 
ATOM   3530 C CB  . ALA B 1 184 ? 24.30500 -16.49800 179.56400 1.000 7.87000  ? 184 ALA B CB  1 
ATOM   3531 N N   . GLY B 1 185 ? 21.94800 -15.39500 177.68500 1.000 7.11000  ? 185 GLY B N   1 
ATOM   3532 C CA  . GLY B 1 185 ? 20.83300 -15.65300 176.79500 1.000 5.72000  ? 185 GLY B CA  1 
ATOM   3533 C C   . GLY B 1 185 ? 21.02500 -15.04300 175.42400 1.000 5.86000  ? 185 GLY B C   1 
ATOM   3534 O O   . GLY B 1 185 ? 20.49600 -15.55900 174.43600 1.000 7.25000  ? 185 GLY B O   1 
ATOM   3535 N N   . GLY B 1 186 ? 21.78000 -13.94300 175.34100 1.000 5.51000  ? 186 GLY B N   1 
ATOM   3536 C CA  . GLY B 1 186 ? 22.11800 -13.38700 174.04000 1.000 6.00000  ? 186 GLY B CA  1 
ATOM   3537 C C   . GLY B 1 186 ? 23.17200 -14.20300 173.32400 1.000 5.30000  ? 186 GLY B C   1 
ATOM   3538 O O   . GLY B 1 186 ? 23.15800 -14.30000 172.09300 1.000 6.08000  ? 186 GLY B O   1 
ATOM   3539 N N   . ASN B 1 187 ? 24.10700 -14.78800 174.08200 1.000 6.34000  ? 187 ASN B N   1 
ATOM   3540 C CA  . ASN B 1 187 ? 24.99100 -15.80800 173.52700 1.000 6.27000  ? 187 ASN B CA  1 
ATOM   3541 C C   . ASN B 1 187 ? 24.17800 -16.96400 172.94900 1.000 6.16000  ? 187 ASN B C   1 
ATOM   3542 O O   . ASN B 1 187 ? 24.37100 -17.36400 171.79100 1.000 6.76000  ? 187 ASN B O   1 
ATOM   3543 C CB  . ASN B 1 187 ? 25.95100 -16.28700 174.62500 1.000 7.17000  ? 187 ASN B CB  1 
ATOM   3544 C CG  . ASN B 1 187 ? 26.84200 -17.43100 174.17600 1.000 7.76000  ? 187 ASN B CG  1 
ATOM   3545 O OD1 . ASN B 1 187 ? 26.44700 -18.59800 174.23600 1.000 8.89000  ? 187 ASN B OD1 1 
ATOM   3546 N ND2 . ASN B 1 187 ? 28.05700 -17.10300 173.74300 1.000 7.77000  ? 187 ASN B ND2 1 
ATOM   3547 N N   . ALA B 1 188 ? 23.23400 -17.49200 173.73600 1.000 6.08000  ? 188 ALA B N   1 
ATOM   3548 C CA  . ALA B 1 188 ? 22.39400 -18.58600 173.25500 1.000 6.44000  ? 188 ALA B CA  1 
ATOM   3549 C C   . ALA B 1 188 ? 21.60500 -18.17900 172.01800 1.000 6.83000  ? 188 ALA B C   1 
ATOM   3550 O O   . ALA B 1 188 ? 21.43400 -18.98000 171.09000 1.000 6.88000  ? 188 ALA B O   1 
ATOM   3551 C CB  . ALA B 1 188 ? 21.44300 -19.04600 174.35800 1.000 7.24000  ? 188 ALA B CB  1 
ATOM   3552 N N   . THR B 1 189 ? 21.09400 -16.94400 171.99800 1.000 6.18000  ? 189 THR B N   1 
ATOM   3553 C CA  . THR B 1 189 ? 20.36700 -16.45400 170.82700 1.000 5.65000  ? 189 THR B CA  1 
ATOM   3554 C C   . THR B 1 189 ? 21.19400 -16.62600 169.55900 1.000 7.01000  ? 189 THR B C   1 
ATOM   3555 O O   . THR B 1 189 ? 20.72900 -17.20100 168.56300 1.000 5.82000  ? 189 THR B O   1 
ATOM   3556 C CB  . THR B 1 189 ? 19.99900 -14.97900 171.03200 1.000 7.53000  ? 189 THR B CB  1 
ATOM   3557 O OG1 . THR B 1 189 ? 19.01200 -14.86400 172.07400 1.000 5.71000  ? 189 THR B OG1 1 
ATOM   3558 C CG2 . THR B 1 189 ? 19.47900 -14.34900 169.73100 1.000 6.10000  ? 189 THR B CG2 1 
ATOM   3559 N N   . VAL B 1 190 ? 22.43500 -16.13500 169.58000 1.000 4.79000  ? 190 VAL B N   1 
ATOM   3560 C CA  . VAL B 1 190 ? 23.24300 -16.17700 168.36600 1.000 6.04000  ? 190 VAL B CA  1 
ATOM   3561 C C   . VAL B 1 190 ? 23.63300 -17.61300 168.02800 1.000 7.05000  ? 190 VAL B C   1 
ATOM   3562 O O   . VAL B 1 190 ? 23.61700 -18.01500 166.85500 1.000 6.70000  ? 190 VAL B O   1 
ATOM   3563 C CB  . VAL B 1 190 ? 24.47700 -15.26600 168.51100 1.000 5.98000  ? 190 VAL B CB  1 
ATOM   3564 C CG1 . VAL B 1 190 ? 25.33800 -15.31600 167.23900 1.000 5.50000  ? 190 VAL B CG1 1 
ATOM   3565 C CG2 . VAL B 1 190 ? 24.03700 -13.83200 168.78100 1.000 6.86000  ? 190 VAL B CG2 1 
ATOM   3566 N N   . VAL B 1 191 ? 23.98200 -18.41100 169.04200 1.000 6.06000  ? 191 VAL B N   1 
ATOM   3567 C CA  . VAL B 1 191 ? 24.37900 -19.79600 168.79100 1.000 6.36000  ? 191 VAL B CA  1 
ATOM   3568 C C   . VAL B 1 191 ? 23.21500 -20.58700 168.20500 1.000 6.27000  ? 191 VAL B C   1 
ATOM   3569 O O   . VAL B 1 191 ? 23.38000 -21.32500 167.23200 1.000 7.11000  ? 191 VAL B O   1 
ATOM   3570 C CB  . VAL B 1 191 ? 24.91700 -20.45700 170.07400 1.000 6.79000  ? 191 VAL B CB  1 
ATOM   3571 C CG1 . VAL B 1 191 ? 25.17600 -21.96400 169.82800 1.000 6.22000  ? 191 VAL B CG1 1 
ATOM   3572 C CG2 . VAL B 1 191 ? 26.19200 -19.76500 170.55300 1.000 7.32000  ? 191 VAL B CG2 1 
ATOM   3573 N N   . VAL B 1 192 ? 22.01600 -20.43500 168.77700 1.000 5.81000  ? 192 VAL B N   1 
ATOM   3574 C CA  . VAL B 1 192 ? 20.85500 -21.15100 168.23800 1.000 6.32000  ? 192 VAL B CA  1 
ATOM   3575 C C   . VAL B 1 192 ? 20.59500 -20.73800 166.79500 1.000 7.74000  ? 192 VAL B C   1 
ATOM   3576 O O   . VAL B 1 192 ? 20.29000 -21.57700 165.93400 1.000 6.75000  ? 192 VAL B O   1 
ATOM   3577 C CB  . VAL B 1 192 ? 19.61900 -20.91600 169.12600 1.000 5.22000  ? 192 VAL B CB  1 
ATOM   3578 C CG1 . VAL B 1 192 ? 18.35100 -21.39400 168.41000 1.000 7.26000  ? 192 VAL B CG1 1 
ATOM   3579 C CG2 . VAL B 1 192 ? 19.78900 -21.63100 170.47500 1.000 6.10000  ? 192 VAL B CG2 1 
ATOM   3580 N N   . GLY B 1 193 ? 20.73700 -19.44500 166.49700 1.000 5.79000  ? 193 GLY B N   1 
ATOM   3581 C CA  . GLY B 1 193 ? 20.54600 -18.99500 165.12700 1.000 5.52000  ? 193 GLY B CA  1 
ATOM   3582 C C   . GLY B 1 193 ? 21.54900 -19.61100 164.16800 1.000 6.76000  ? 193 GLY B C   1 
ATOM   3583 O O   . GLY B 1 193 ? 21.21800 -19.90700 163.01800 1.000 8.37000  ? 193 GLY B O   1 
ATOM   3584 N N   . GLN B 1 194 ? 22.78400 -19.82400 164.63300 1.000 6.34000  ? 194 GLN B N   1 
ATOM   3585 C CA  . GLN B 1 194 ? 23.79500 -20.45100 163.78200 1.000 6.94000  ? 194 GLN B CA  1 
ATOM   3586 C C   . GLN B 1 194 ? 23.53700 -21.94300 163.61200 1.000 8.33000  ? 194 GLN B C   1 
ATOM   3587 O O   . GLN B 1 194 ? 23.76200 -22.49300 162.52800 1.000 8.40000  ? 194 GLN B O   1 
ATOM   3588 C CB  . GLN B 1 194 ? 25.19300 -20.20800 164.36300 1.000 7.85000  ? 194 GLN B CB  1 
ATOM   3589 C CG  . GLN B 1 194 ? 25.65400 -18.76600 164.18100 1.000 9.08000  ? 194 GLN B CG  1 
ATOM   3590 C CD  . GLN B 1 194 ? 27.01300 -18.48400 164.79400 1.000 9.74000  ? 194 GLN B CD  1 
ATOM   3591 O OE1 . GLN B 1 194 ? 27.67300 -19.38000 165.33700 1.000 11.05000 ? 194 GLN B OE1 1 
ATOM   3592 N NE2 . GLN B 1 194 ? 27.44100 -17.22700 164.71400 1.000 7.58000  ? 194 GLN B NE2 1 
ATOM   3593 N N   . LEU B 1 195 ? 23.08100 -22.61800 164.67400 1.000 7.30000  ? 195 LEU B N   1 
ATOM   3594 C CA  . LEU B 1 195 ? 22.78200 -24.04300 164.56000 1.000 7.08000  ? 195 LEU B CA  1 
ATOM   3595 C C   . LEU B 1 195 ? 21.59400 -24.27600 163.63800 1.000 9.09000  ? 195 LEU B C   1 
ATOM   3596 O O   . LEU B 1 195 ? 21.57400 -25.25100 162.87800 1.000 11.61000 ? 195 LEU B O   1 
ATOM   3597 C CB  . LEU B 1 195 ? 22.51600 -24.64800 165.94200 1.000 8.39000  ? 195 LEU B CB  1 
ATOM   3598 C CG  . LEU B 1 195 ? 23.74200 -24.71300 166.85100 1.000 8.38000  ? 195 LEU B CG  1 
ATOM   3599 C CD1 . LEU B 1 195 ? 23.35800 -24.97300 168.32200 1.000 10.10000 ? 195 LEU B CD1 1 
ATOM   3600 C CD2 . LEU B 1 195 ? 24.71300 -25.76700 166.34700 1.000 11.62000 ? 195 LEU B CD2 1 
ATOM   3601 N N   . LEU B 1 196 ? 20.60500 -23.38100 163.67500 1.000 7.07000  ? 196 LEU B N   1 
ATOM   3602 C CA  . LEU B 1 196 ? 19.44900 -23.52100 162.80000 1.000 9.74000  ? 196 LEU B CA  1 
ATOM   3603 C C   . LEU B 1 196 ? 19.74100 -23.03900 161.38500 1.000 11.04000 ? 196 LEU B C   1 
ATOM   3604 O O   . LEU B 1 196 ? 19.13800 -23.54500 160.43200 1.000 11.94000 ? 196 LEU B O   1 
ATOM   3605 C CB  . LEU B 1 196 ? 18.25200 -22.76700 163.38200 1.000 7.50000  ? 196 LEU B CB  1 
ATOM   3606 C CG  . LEU B 1 196 ? 17.32700 -23.59400 164.28300 1.000 8.30000  ? 196 LEU B CG  1 
ATOM   3607 C CD1 . LEU B 1 196 ? 18.08200 -24.22700 165.44800 1.000 11.39000 ? 196 LEU B CD1 1 
ATOM   3608 C CD2 . LEU B 1 196 ? 16.18900 -22.72700 164.78600 1.000 9.44000  ? 196 LEU B CD2 1 
ATOM   3609 N N   . ALA B 1 197 ? 20.63800 -22.06500 161.21800 1.000 8.56000  ? 197 ALA B N   1 
ATOM   3610 C CA  . ALA B 1 197 ? 21.03700 -21.68100 159.86500 1.000 11.57000 ? 197 ALA B CA  1 
ATOM   3611 C C   . ALA B 1 197 ? 21.70400 -22.84900 159.15700 1.000 15.54000 ? 197 ALA B C   1 
ATOM   3612 O O   . ALA B 1 197 ? 21.48500 -23.07000 157.95800 1.000 12.67000 ? 197 ALA B O   1 
ATOM   3613 C CB  . ALA B 1 197 ? 21.98200 -20.48200 159.89400 1.000 8.34000  ? 197 ALA B CB  1 
ATOM   3614 N N   . ALA B 1 198 ? 22.51700 -23.61100 159.89100 1.000 11.98000 ? 198 ALA B N   1 
ATOM   3615 C CA  . ALA B 1 198 ? 23.23900 -24.73700 159.31400 1.000 14.00000 ? 198 ALA B CA  1 
ATOM   3616 C C   . ALA B 1 198 ? 22.32400 -25.92400 159.04800 1.000 16.52000 ? 198 ALA B C   1 
ATOM   3617 O O   . ALA B 1 198 ? 22.55600 -26.67800 158.09500 1.000 17.90000 ? 198 ALA B O   1 
ATOM   3618 C CB  . ALA B 1 198 ? 24.38300 -25.14600 160.24000 1.000 13.95000 ? 198 ALA B CB  1 
ATOM   3619 N N   . SER B 1 199 ? 21.29300 -26.09900 159.87100 1.000 13.26000 ? 199 SER B N   1 
ATOM   3620 C CA  . SER B 1 199 ? 20.34300 -27.20100 159.71800 1.000 15.19000 ? 199 SER B CA  1 
ATOM   3621 C C   . SER B 1 199 ? 18.97900 -26.67600 160.14100 1.000 12.68000 ? 199 SER B C   1 
ATOM   3622 O O   . SER B 1 199 ? 18.64600 -26.65200 161.33500 1.000 14.46000 ? 199 SER B O   1 
ATOM   3623 C CB  . SER B 1 199 ? 20.75200 -28.41800 160.54700 1.000 17.67000 ? 199 SER B CB  1 
ATOM   3624 O OG  . SER B 1 199 ? 19.78300 -29.44700 160.47300 1.000 23.14000 ? 199 SER B OG  1 
ATOM   3625 N N   . PRO B 1 200 ? 18.17300 -26.20500 159.18600 1.000 12.74000 ? 200 PRO B N   1 
ATOM   3626 C CA  . PRO B 1 200 ? 16.97500 -25.43000 159.54000 1.000 12.78000 ? 200 PRO B CA  1 
ATOM   3627 C C   . PRO B 1 200 ? 15.93400 -26.22000 160.31500 1.000 14.91000 ? 200 PRO B C   1 
ATOM   3628 O O   . PRO B 1 200 ? 15.78700 -27.43500 160.16100 1.000 15.75000 ? 200 PRO B O   1 
ATOM   3629 C CB  . PRO B 1 200 ? 16.43100 -24.98700 158.17700 1.000 15.58000 ? 200 PRO B CB  1 
ATOM   3630 C CG  . PRO B 1 200 ? 17.65600 -24.91200 157.31500 1.000 18.16000 ? 200 PRO B CG  1 
ATOM   3631 C CD  . PRO B 1 200 ? 18.50500 -26.07400 157.75600 1.000 16.26000 ? 200 PRO B CD  1 
ATOM   3632 N N   . ALA B 1 201 ? 15.20400 -25.49600 161.16100 1.000 11.69000 ? 201 ALA B N   1 
ATOM   3633 C CA  . ALA B 1 201 ? 14.03500 -26.03400 161.84100 1.000 10.73000 ? 201 ALA B CA  1 
ATOM   3634 C C   . ALA B 1 201 ? 12.84000 -25.96200 160.88800 1.000 12.22000 ? 201 ALA B C   1 
ATOM   3635 O O   . ALA B 1 201 ? 12.97300 -25.59300 159.71600 1.000 12.90000 ? 201 ALA B O   1 
ATOM   3636 C CB  . ALA B 1 201 ? 13.78900 -25.27900 163.14500 1.000 9.86000  ? 201 ALA B CB  1 
ATOM   3637 N N   . ALA B 1 202 ? 11.65000 -26.30100 161.39100 1.000 13.12000 ? 202 ALA B N   1 
ATOM   3638 C CA  . ALA B 1 202 ? 10.46500 -26.37200 160.53600 1.000 15.38000 ? 202 ALA B CA  1 
ATOM   3639 C C   . ALA B 1 202 ? 10.08600 -25.01000 159.96100 1.000 15.37000 ? 202 ALA B C   1 
ATOM   3640 O O   . ALA B 1 202 ? 9.49900  -24.94100 158.87500 1.000 12.91000 ? 202 ALA B O   1 
ATOM   3641 C CB  . ALA B 1 202 ? 9.29400  -26.96500 161.32200 1.000 13.05000 ? 202 ALA B CB  1 
ATOM   3642 N N   . VAL B 1 203 ? 10.38000 -23.92900 160.67700 1.000 11.70000 ? 203 VAL B N   1 
ATOM   3643 C CA  . VAL B 1 203 ? 10.21400 -22.56500 160.17200 1.000 11.03000 ? 203 VAL B CA  1 
ATOM   3644 C C   . VAL B 1 203 ? 11.51400 -21.81700 160.43200 1.000 11.84000 ? 203 VAL B C   1 
ATOM   3645 O O   . VAL B 1 203 ? 12.31200 -22.22300 161.29300 1.000 10.60000 ? 203 VAL B O   1 
ATOM   3646 C CB  . VAL B 1 203 ? 9.01500  -21.84200 160.83400 1.000 10.55000 ? 203 VAL B CB  1 
ATOM   3647 C CG1 . VAL B 1 203 ? 7.68900  -22.54700 160.51700 1.000 11.63000 ? 203 VAL B CG1 1 
ATOM   3648 C CG2 . VAL B 1 203 ? 9.22100  -21.71700 162.33300 1.000 10.04000 ? 203 VAL B CG2 1 
ATOM   3649 N N   . PRO B 1 204 ? 11.76600 -20.73000 159.70500 1.000 10.29000 ? 204 PRO B N   1 
ATOM   3650 C CA  . PRO B 1 204 ? 13.03400 -20.01200 159.87100 1.000 9.49000  ? 204 PRO B CA  1 
ATOM   3651 C C   . PRO B 1 204 ? 13.04300 -19.09900 161.09200 1.000 8.11000  ? 204 PRO B C   1 
ATOM   3652 O O   . PRO B 1 204 ? 12.00900 -18.67600 161.60600 1.000 8.97000  ? 204 PRO B O   1 
ATOM   3653 C CB  . PRO B 1 204 ? 13.13600 -19.18700 158.58500 1.000 15.15000 ? 204 PRO B CB  1 
ATOM   3654 C CG  . PRO B 1 204 ? 11.71900 -18.90200 158.23500 1.000 15.79000 ? 204 PRO B CG  1 
ATOM   3655 C CD  . PRO B 1 204 ? 10.95100 -20.15400 158.61900 1.000 13.58000 ? 204 PRO B CD  1 
ATOM   3656 N N   . VAL B 1 205 ? 14.25600 -18.79100 161.55000 1.000 8.27000  ? 205 VAL B N   1 
ATOM   3657 C CA  . VAL B 1 205 ? 14.43100 -17.66100 162.45800 1.000 5.54000  ? 205 VAL B CA  1 
ATOM   3658 C C   . VAL B 1 205 ? 14.23000 -16.38700 161.64100 1.000 6.66000  ? 205 VAL B C   1 
ATOM   3659 O O   . VAL B 1 205 ? 14.99200 -16.11100 160.70900 1.000 10.94000 ? 205 VAL B O   1 
ATOM   3660 C CB  . VAL B 1 205 ? 15.80300 -17.68500 163.14100 1.000 6.87000  ? 205 VAL B CB  1 
ATOM   3661 C CG1 . VAL B 1 205 ? 15.97200 -16.45200 164.05100 1.000 7.59000  ? 205 VAL B CG1 1 
ATOM   3662 C CG2 . VAL B 1 205 ? 15.95900 -18.96600 163.94800 1.000 9.02000  ? 205 VAL B CG2 1 
ATOM   3663 N N   . VAL B 1 206 ? 13.18100 -15.61900 161.96000 1.000 6.11000  ? 206 VAL B N   1 
ATOM   3664 C CA  . VAL B 1 206 ? 12.87900 -14.40600 161.19600 1.000 6.54000  ? 206 VAL B CA  1 
ATOM   3665 C C   . VAL B 1 206 ? 13.45300 -13.14800 161.83400 1.000 8.54000  ? 206 VAL B C   1 
ATOM   3666 O O   . VAL B 1 206 ? 13.44900 -12.08400 161.19600 1.000 8.09000  ? 206 VAL B O   1 
ATOM   3667 C CB  . VAL B 1 206 ? 11.36000 -14.23300 160.99700 1.000 10.63000 ? 206 VAL B CB  1 
ATOM   3668 C CG1 . VAL B 1 206 ? 10.81200 -15.37300 160.13800 1.000 12.29000 ? 206 VAL B CG1 1 
ATOM   3669 C CG2 . VAL B 1 206 ? 10.64500 -14.17500 162.34500 1.000 8.26000  ? 206 VAL B CG2 1 
ATOM   3670 N N   . LEU B 1 207 ? 13.97600 -13.24200 163.05600 1.000 6.42000  ? 207 LEU B N   1 
ATOM   3671 C CA  . LEU B 1 207 ? 14.56700 -12.10700 163.75400 1.000 4.78000  ? 207 LEU B CA  1 
ATOM   3672 C C   . LEU B 1 207 ? 15.28300 -12.64300 164.97900 1.000 5.43000  ? 207 LEU B C   1 
ATOM   3673 O O   . LEU B 1 207 ? 14.76100 -13.52300 165.66300 1.000 5.70000  ? 207 LEU B O   1 
ATOM   3674 C CB  . LEU B 1 207 ? 13.50400 -11.07500 164.17900 1.000 6.76000  ? 207 LEU B CB  1 
ATOM   3675 C CG  . LEU B 1 207 ? 13.99700 -9.85900  164.98300 1.000 5.89000  ? 207 LEU B CG  1 
ATOM   3676 C CD1 . LEU B 1 207 ? 14.93600 -8.98600  164.14000 1.000 5.97000  ? 207 LEU B CD1 1 
ATOM   3677 C CD2 . LEU B 1 207 ? 12.83900 -9.02700  165.55200 1.000 6.50000  ? 207 LEU B CD2 1 
ATOM   3678 N N   . GLN B 1 208 ? 16.47800 -12.12600 165.24200 1.000 6.77000  ? 208 GLN B N   1 
ATOM   3679 C CA  . GLN B 1 208 ? 17.20700 -12.46600 166.45600 1.000 4.78000  ? 208 GLN B CA  1 
ATOM   3680 C C   . GLN B 1 208 ? 17.60400 -11.17500 167.15600 1.000 5.78000  ? 208 GLN B C   1 
ATOM   3681 O O   . GLN B 1 208 ? 18.02100 -10.21000 166.50600 1.000 4.41000  ? 208 GLN B O   1 
ATOM   3682 C CB  . GLN B 1 208 ? 18.44600 -13.33700 166.16000 1.000 5.67000  ? 208 GLN B CB  1 
ATOM   3683 C CG  . GLN B 1 208 ? 19.51400 -12.67000 165.30900 1.000 6.40000  ? 208 GLN B CG  1 
ATOM   3684 C CD  . GLN B 1 208 ? 20.78900 -13.49900 165.20500 1.000 7.95000  ? 208 GLN B CD  1 
ATOM   3685 O OE1 . GLN B 1 208 ? 20.85600 -14.62100 165.70600 1.000 8.69000  ? 208 GLN B OE1 1 
ATOM   3686 N NE2 . GLN B 1 208 ? 21.80700 -12.94500 164.53800 1.000 7.29000  ? 208 GLN B NE2 1 
ATOM   3687 N N   . VAL B 1 209 ? 17.44400 -11.16400 168.47900 1.000 5.14000  ? 209 VAL B N   1 
ATOM   3688 C CA  . VAL B 1 209 ? 17.63200 -9.97700  169.31300 1.000 3.82000  ? 209 VAL B CA  1 
ATOM   3689 C C   . VAL B 1 209 ? 18.55800 -10.32400 170.47800 1.000 4.88000  ? 209 VAL B C   1 
ATOM   3690 O O   . VAL B 1 209 ? 18.09200 -10.53000 171.60900 1.000 5.03000  ? 209 VAL B O   1 
ATOM   3691 C CB  . VAL B 1 209 ? 16.27600 -9.43200  169.80500 1.000 4.47000  ? 209 VAL B CB  1 
ATOM   3692 C CG1 . VAL B 1 209 ? 16.45400 -8.06100  170.46000 1.000 5.04000  ? 209 VAL B CG1 1 
ATOM   3693 C CG2 . VAL B 1 209 ? 15.27100 -9.34100  168.63900 1.000 4.23000  ? 209 VAL B CG2 1 
ATOM   3694 N N   . PRO B 1 210 ? 19.87000 -10.42200 170.24800 1.000 5.96000  ? 210 PRO B N   1 
ATOM   3695 C CA  . PRO B 1 210 ? 20.81800 -10.63100 171.35900 1.000 5.35000  ? 210 PRO B CA  1 
ATOM   3696 C C   . PRO B 1 210 ? 21.04500 -9.32600  172.11400 1.000 6.40000  ? 210 PRO B C   1 
ATOM   3697 O O   . PRO B 1 210 ? 21.48500 -8.32800  171.53900 1.000 7.29000  ? 210 PRO B O   1 
ATOM   3698 C CB  . PRO B 1 210 ? 22.09500 -11.11000 170.65000 1.000 6.54000  ? 210 PRO B CB  1 
ATOM   3699 C CG  . PRO B 1 210 ? 21.99600 -10.51100 169.25100 1.000 6.42000  ? 210 PRO B CG  1 
ATOM   3700 C CD  . PRO B 1 210 ? 20.52200 -10.49100 168.92200 1.000 6.68000  ? 210 PRO B CD  1 
ATOM   3701 N N   . ILE B 1 211 ? 20.76800 -9.34100  173.41700 1.000 6.72000  ? 211 ILE B N   1 
ATOM   3702 C CA  . ILE B 1 211 ? 20.78800 -8.14600  174.25400 1.000 6.06000  ? 211 ILE B CA  1 
ATOM   3703 C C   . ILE B 1 211 ? 21.95000 -8.26200  175.23000 1.000 7.35000  ? 211 ILE B C   1 
ATOM   3704 O O   . ILE B 1 211 ? 22.04100 -9.25100  175.96700 1.000 7.61000  ? 211 ILE B O   1 
ATOM   3705 C CB  . ILE B 1 211 ? 19.45600 -7.98300  175.00300 1.000 7.83000  ? 211 ILE B CB  1 
ATOM   3706 C CG1 . ILE B 1 211 ? 18.30700 -7.85600  173.99900 1.000 8.30000  ? 211 ILE B CG1 1 
ATOM   3707 C CG2 . ILE B 1 211 ? 19.48500 -6.77500  175.92700 1.000 8.05000  ? 211 ILE B CG2 1 
ATOM   3708 C CD1 . ILE B 1 211 ? 16.95100 -7.94400  174.66400 1.000 7.61000  ? 211 ILE B CD1 1 
ATOM   3709 N N   . PHE B 1 212 ? 22.80200 -7.21200  175.27800 1.000 5.68000  ? 212 PHE B N   1 
ATOM   3710 C CA  . PHE B 1 212 ? 24.14300 -7.21400  175.87300 1.000 8.36000  ? 212 PHE B CA  1 
ATOM   3711 C C   . PHE B 1 212 ? 24.71900 -8.63000  175.87400 1.000 8.36000  ? 212 PHE B C   1 
ATOM   3712 O O   . PHE B 1 212 ? 25.03200 -9.19300  176.93500 1.000 8.89000  ? 212 PHE B O   1 
ATOM   3713 C CB  . PHE B 1 212 ? 24.19700 -6.57600  177.28500 1.000 9.71000  ? 212 PHE B CB  1 
ATOM   3714 C CG  . PHE B 1 212 ? 22.94500 -6.72700  178.13200 1.000 8.57000  ? 212 PHE B CG  1 
ATOM   3715 C CD1 . PHE B 1 212 ? 22.74900 -7.86300  178.90900 1.000 9.17000  ? 212 PHE B CD1 1 
ATOM   3716 C CD2 . PHE B 1 212 ? 22.02300 -5.68800  178.22700 1.000 10.28000 ? 212 PHE B CD2 1 
ATOM   3717 C CE1 . PHE B 1 212 ? 21.62000 -7.98700  179.71700 1.000 9.28000  ? 212 PHE B CE1 1 
ATOM   3718 C CE2 . PHE B 1 212 ? 20.88300 -5.80600  179.01700 1.000 7.01000  ? 212 PHE B CE2 1 
ATOM   3719 C CZ  . PHE B 1 212 ? 20.67500 -6.95900  179.75600 1.000 8.76000  ? 212 PHE B CZ  1 
ATOM   3720 N N   . PRO B 1 213 ? 24.91100 -9.21600  174.69400 1.000 6.42000  ? 213 PRO B N   1 
ATOM   3721 C CA  . PRO B 1 213 ? 25.32500 -10.61900 174.60900 1.000 8.68000  ? 213 PRO B CA  1 
ATOM   3722 C C   . PRO B 1 213 ? 26.82900 -10.81500 174.77700 1.000 10.71000 ? 213 PRO B C   1 
ATOM   3723 O O   . PRO B 1 213 ? 27.64400 -9.91000  174.57300 1.000 8.62000  ? 213 PRO B O   1 
ATOM   3724 C CB  . PRO B 1 213 ? 24.89700 -11.00400 173.19000 1.000 8.01000  ? 213 PRO B CB  1 
ATOM   3725 C CG  . PRO B 1 213 ? 25.17200 -9.72200  172.40700 1.000 8.61000  ? 213 PRO B CG  1 
ATOM   3726 C CD  . PRO B 1 213 ? 24.79500 -8.59200  173.35500 1.000 4.81000  ? 213 PRO B CD  1 
ATOM   3727 N N   . LEU B 1 214 ? 27.19200 -12.04500 175.13900 1.000 8.66000  ? 214 LEU B N   1 
ATOM   3728 C CA  . LEU B 1 214 ? 28.56800 -12.50900 174.99900 1.000 6.69000  ? 214 LEU B CA  1 
ATOM   3729 C C   . LEU B 1 214 ? 28.67900 -13.23200 173.65700 1.000 9.24000  ? 214 LEU B C   1 
ATOM   3730 O O   . LEU B 1 214 ? 28.10700 -14.30900 173.47800 1.000 11.44000 ? 214 LEU B O   1 
ATOM   3731 C CB  . LEU B 1 214 ? 28.95200 -13.42100 176.16300 1.000 9.18000  ? 214 LEU B CB  1 
ATOM   3732 C CG  . LEU B 1 214 ? 30.42500 -13.83700 176.18600 1.000 10.92000 ? 214 LEU B CG  1 
ATOM   3733 C CD1 . LEU B 1 214 ? 31.30700 -12.66900 176.60000 1.000 11.55000 ? 214 LEU B CD1 1 
ATOM   3734 C CD2 . LEU B 1 214 ? 30.62200 -15.04200 177.11100 1.000 18.65000 ? 214 LEU B CD2 1 
ATOM   3735 N N   . VAL B 1 215 ? 29.39600 -12.63500 172.70100 1.000 10.01000 ? 215 VAL B N   1 
ATOM   3736 C CA  . VAL B 1 215 ? 29.57300 -13.21200 171.37200 1.000 9.24000  ? 215 VAL B CA  1 
ATOM   3737 C C   . VAL B 1 215 ? 31.04100 -13.50400 171.08800 1.000 11.13000 ? 215 VAL B C   1 
ATOM   3738 O O   . VAL B 1 215 ? 31.40600 -14.62600 170.71500 1.000 8.76000  ? 215 VAL B O   1 
ATOM   3739 C CB  . VAL B 1 215 ? 28.97900 -12.29800 170.27700 1.000 8.49000  ? 215 VAL B CB  1 
ATOM   3740 C CG1 . VAL B 1 215 ? 29.24900 -12.88800 168.88800 1.000 8.88000  ? 215 VAL B CG1 1 
ATOM   3741 C CG2 . VAL B 1 215 ? 27.48500 -12.10300 170.50400 1.000 11.46000 ? 215 VAL B CG2 1 
ATOM   3742 N N   . ALA B 1 216 ? 31.89700 -12.50500 171.25700 1.000 9.16000  ? 216 ALA B N   1 
ATOM   3743 C CA  . ALA B 1 216 ? 33.33500 -12.69500 171.22600 1.000 12.55000 ? 216 ALA B CA  1 
ATOM   3744 C C   . ALA B 1 216 ? 33.85900 -12.75500 172.65400 1.000 12.76000 ? 216 ALA B C   1 
ATOM   3745 O O   . ALA B 1 216 ? 33.27000 -12.18300 173.57700 1.000 10.98000 ? 216 ALA B O   1 
ATOM   3746 C CB  . ALA B 1 216 ? 34.02200 -11.56900 170.44900 1.000 9.77000  ? 216 ALA B CB  1 
ATOM   3747 N N   . ASP B 1 217 ? 34.95700 -13.48100 172.83600 1.000 12.35000 ? 217 ASP B N   1 
ATOM   3748 C CA  . ASP B 1 217 ? 35.60200 -13.54600 174.14200 1.000 14.18000 ? 217 ASP B CA  1 
ATOM   3749 C C   . ASP B 1 217 ? 35.92300 -12.13900 174.63500 1.000 14.67000 ? 217 ASP B C   1 
ATOM   3750 O O   . ASP B 1 217 ? 36.50200 -11.32900 173.90900 1.000 14.92000 ? 217 ASP B O   1 
ATOM   3751 C CB  . ASP B 1 217 ? 36.87700 -14.39100 174.04100 1.000 14.84000 ? 217 ASP B CB  1 
ATOM   3752 C CG  . ASP B 1 217 ? 37.40300 -14.84800 175.39300 1.000 22.22000 ? 217 ASP B CG  1 
ATOM   3753 O OD1 . ASP B 1 217 ? 36.86000 -14.42500 176.43500 1.000 26.26000 ? 217 ASP B OD1 1 
ATOM   3754 O OD2 . ASP B 1 217 ? 38.37700 -15.63900 175.40600 1.000 22.44000 ? 217 ASP B OD2 1 
ATOM   3755 N N   . ALA B 1 218 ? 35.51900 -11.84400 175.86700 1.000 15.68000 ? 218 ALA B N   1 
ATOM   3756 C CA  . ALA B 1 218 ? 35.66100 -10.50100 176.41700 1.000 18.26000 ? 218 ALA B CA  1 
ATOM   3757 C C   . ALA B 1 218 ? 36.97100 -10.28000 177.17100 1.000 23.55000 ? 218 ALA B C   1 
ATOM   3758 O O   . ALA B 1 218 ? 37.26600 -9.13500  177.53600 1.000 18.36000 ? 218 ALA B O   1 
ATOM   3759 C CB  . ALA B 1 218 ? 34.48300 -10.20300 177.35200 1.000 16.14000 ? 218 ALA B CB  1 
ATOM   3760 N N   . VAL B 1 219 ? 37.78800 -11.32500 177.34700 1.000 21.45000 ? 219 VAL B N   1 
ATOM   3761 C CA  . VAL B 1 219 ? 38.80900 -11.33100 178.39900 1.000 28.06000 ? 219 VAL B CA  1 
ATOM   3762 C C   . VAL B 1 219 ? 39.74900 -10.12800 178.28400 1.000 30.94000 ? 219 VAL B C   1 
ATOM   3763 O O   . VAL B 1 219 ? 40.01700 -9.43700  179.27800 1.000 38.85000 ? 219 VAL B O   1 
ATOM   3764 C CB  . VAL B 1 219 ? 39.57700 -12.66400 178.38500 1.000 26.80000 ? 219 VAL B CB  1 
ATOM   3765 C CG1 . VAL B 1 219 ? 40.92800 -12.50900 179.06200 1.000 31.60000 ? 219 VAL B CG1 1 
ATOM   3766 C CG2 . VAL B 1 219 ? 38.74900 -13.74200 179.07800 1.000 28.44000 ? 219 VAL B CG2 1 
ATOM   3767 N N   . SER B 1 220 ? 40.26900 -9.85200  177.08300 1.000 26.45000 ? 220 SER B N   1 
ATOM   3768 C CA  . SER B 1 220 ? 41.23100 -8.76400  176.90600 1.000 28.10000 ? 220 SER B CA  1 
ATOM   3769 C C   . SER B 1 220 ? 40.64900 -7.55700  176.17700 1.000 24.89000 ? 220 SER B C   1 
ATOM   3770 O O   . SER B 1 220 ? 41.39900 -6.76600  175.59400 1.000 24.35000 ? 220 SER B O   1 
ATOM   3771 C CB  . SER B 1 220 ? 42.48200 -9.26300  176.17300 1.000 29.40000 ? 220 SER B CB  1 
ATOM   3772 O OG  . SER B 1 220 ? 42.85900 -10.54900 176.63100 1.000 41.03000 ? 220 SER B OG  1 
ATOM   3773 N N   . SER B 1 221 ? 39.33500 -7.37800  176.22600 1.000 22.33000 ? 221 SER B N   1 
ATOM   3774 C CA  . SER B 1 221 ? 38.69100 -6.24400  175.58600 1.000 19.70000 ? 221 SER B CA  1 
ATOM   3775 C C   . SER B 1 221 ? 38.90600 -4.96200  176.38700 1.000 17.45000 ? 221 SER B C   1 
ATOM   3776 O O   . SER B 1 221 ? 39.11900 -4.98100  177.60500 1.000 16.97000 ? 221 SER B O   1 
ATOM   3777 C CB  . SER B 1 221 ? 37.19500 -6.50700  175.44900 1.000 17.25000 ? 221 SER B CB  1 
ATOM   3778 O OG  . SER B 1 221 ? 36.60000 -6.55900  176.73400 1.000 14.55000 ? 221 SER B OG  1 
ATOM   3779 N N   . GLU B 1 222 ? 38.81100 -3.82800  175.68700 1.000 18.32000 ? 222 GLU B N   1 
ATOM   3780 C CA  . GLU B 1 222 ? 38.91100 -2.54100  176.36900 1.000 18.11000 ? 222 GLU B CA  1 
ATOM   3781 C C   . GLU B 1 222 ? 37.75000 -2.32500  177.32800 1.000 19.26000 ? 222 GLU B C   1 
ATOM   3782 O O   . GLU B 1 222 ? 37.93700 -1.75900  178.40700 1.000 15.01000 ? 222 GLU B O   1 
ATOM   3783 C CB  . GLU B 1 222 ? 38.97600 -1.39200  175.36500 1.000 20.86000 ? 222 GLU B CB  1 
ATOM   3784 C CG  . GLU B 1 222 ? 39.00400 -0.01100  176.03400 1.000 27.36000 ? 222 GLU B CG  1 
ATOM   3785 C CD  . GLU B 1 222 ? 40.09000 0.10800   177.11000 1.000 42.39000 ? 222 GLU B CD  1 
ATOM   3786 O OE1 . GLU B 1 222 ? 41.28300 -0.06600  176.77000 1.000 48.71000 ? 222 GLU B OE1 1 
ATOM   3787 O OE2 . GLU B 1 222 ? 39.75400 0.36900   178.29200 1.000 31.58000 ? 222 GLU B OE2 1 
ATOM   3788 N N   . SER B 1 223 ? 36.54100 -2.75000  176.96000 1.000 13.22000 ? 223 SER B N   1 
ATOM   3789 C CA  . SER B 1 223 ? 35.43100 -2.54900  177.88500 1.000 10.90000 ? 223 SER B CA  1 
ATOM   3790 C C   . SER B 1 223 ? 35.64800 -3.36500  179.15900 1.000 10.54000 ? 223 SER B C   1 
ATOM   3791 O O   . SER B 1 223 ? 35.28800 -2.92500  180.25800 1.000 10.09000 ? 223 SER B O   1 
ATOM   3792 C CB  . SER B 1 223 ? 34.08700 -2.89700  177.24600 1.000 9.68000  ? 223 SER B CB  1 
ATOM   3793 O OG  . SER B 1 223 ? 34.04200 -4.21600  176.71800 1.000 8.59000  ? 223 SER B OG  1 
ATOM   3794 N N   . MET B 1 224 ? 36.24500 -4.55800  179.04500 1.000 12.34000 ? 224 MET B N   1 
ATOM   3795 C CA  . MET B 1 224 ? 36.49800 -5.34600  180.25100 1.000 13.47000 ? 224 MET B CA  1 
ATOM   3796 C C   . MET B 1 224 ? 37.43900 -4.60400  181.18800 1.000 13.35000 ? 224 MET B C   1 
ATOM   3797 O O   . MET B 1 224 ? 37.22600 -4.59100  182.40300 1.000 15.86000 ? 224 MET B O   1 
ATOM   3798 C CB  . MET B 1 224 ? 37.05400 -6.72300  179.88600 1.000 14.76000 ? 224 MET B CB  1 
ATOM   3799 C CG  . MET B 1 224 ? 37.32000 -7.62900  181.09000 1.000 18.20000 ? 224 MET B CG  1 
ATOM   3800 S SD  . MET B 1 224 ? 35.81500 -8.13500  181.93900 1.000 24.56000 ? 224 MET B SD  1 
ATOM   3801 C CE  . MET B 1 224 ? 34.79400 -8.65500  180.58000 1.000 20.13000 ? 224 MET B CE  1 
ATOM   3802 N N   . ALA B 1 225 ? 38.46500 -3.94400  180.64100 1.000 14.69000 ? 225 ALA B N   1 
ATOM   3803 C CA  . ALA B 1 225 ? 39.38100 -3.18100  181.48800 1.000 16.24000 ? 225 ALA B CA  1 
ATOM   3804 C C   . ALA B 1 225 ? 38.69300 -1.96500  182.10300 1.000 17.51000 ? 225 ALA B C   1 
ATOM   3805 O O   . ALA B 1 225 ? 38.92700 -1.63300  183.27300 1.000 18.54000 ? 225 ALA B O   1 
ATOM   3806 C CB  . ALA B 1 225 ? 40.60700 -2.75800  180.68100 1.000 15.47000 ? 225 ALA B CB  1 
ATOM   3807 N N   . ALA B 1 226 ? 37.81600 -1.30600  181.34500 1.000 13.51000 ? 226 ALA B N   1 
ATOM   3808 C CA  . ALA B 1 226 ? 37.25000 -0.03700  181.79200 1.000 14.84000 ? 226 ALA B CA  1 
ATOM   3809 C C   . ALA B 1 226 ? 36.10800 -0.20700  182.78600 1.000 13.78000 ? 226 ALA B C   1 
ATOM   3810 O O   . ALA B 1 226 ? 35.93400 0.64600   183.66500 1.000 13.33000 ? 226 ALA B O   1 
ATOM   3811 C CB  . ALA B 1 226 ? 36.76700 0.77500   180.58600 1.000 14.10000 ? 226 ALA B CB  1 
ATOM   3812 N N   . PHE B 1 227 ? 35.32300 -1.28100  182.68400 1.000 11.67000 ? 227 PHE B N   1 
ATOM   3813 C CA  . PHE B 1 227 ? 34.10100 -1.40300  183.47300 1.000 12.36000 ? 227 PHE B CA  1 
ATOM   3814 C C   . PHE B 1 227 ? 34.07500 -2.65200  184.34300 1.000 11.07000 ? 227 PHE B C   1 
ATOM   3815 O O   . PHE B 1 227 ? 33.00000 -3.11200  184.72000 1.000 15.51000 ? 227 PHE B O   1 
ATOM   3816 C CB  . PHE B 1 227 ? 32.87300 -1.38000  182.56100 1.000 9.74000  ? 227 PHE B CB  1 
ATOM   3817 C CG  . PHE B 1 227 ? 32.85200 -0.21100  181.63700 1.000 11.62000 ? 227 PHE B CG  1 
ATOM   3818 C CD1 . PHE B 1 227 ? 32.74300 1.07700   182.13600 1.000 15.10000 ? 227 PHE B CD1 1 
ATOM   3819 C CD2 . PHE B 1 227 ? 32.98200 -0.39000  180.27300 1.000 10.78000 ? 227 PHE B CD2 1 
ATOM   3820 C CE1 . PHE B 1 227 ? 32.74300 2.16600   181.28600 1.000 14.19000 ? 227 PHE B CE1 1 
ATOM   3821 C CE2 . PHE B 1 227 ? 32.98200 0.70500   179.41700 1.000 12.72000 ? 227 PHE B CE2 1 
ATOM   3822 C CZ  . PHE B 1 227 ? 32.86500 1.98200   179.93700 1.000 14.90000 ? 227 PHE B CZ  1 
ATOM   3823 N N   . SER B 1 228 ? 35.24600 -3.17900  184.70900 1.000 14.18000 ? 228 SER B N   1 
ATOM   3824 C CA  . SER B 1 228 ? 35.30600 -4.45400  185.42400 1.000 19.36000 ? 228 SER B CA  1 
ATOM   3825 C C   . SER B 1 228 ? 34.84600 -4.35800  186.87500 1.000 15.65000 ? 228 SER B C   1 
ATOM   3826 O O   . SER B 1 228 ? 34.58600 -5.39800  187.49100 1.000 12.87000 ? 228 SER B O   1 
ATOM   3827 C CB  . SER B 1 228 ? 36.72900 -5.01200  185.38300 1.000 16.08000 ? 228 SER B CB  1 
ATOM   3828 O OG  . SER B 1 228 ? 37.59600 -4.23300  186.19500 1.000 31.59000 ? 228 SER B OG  1 
ATOM   3829 N N   . GLU B 1 229 ? 34.76700 -3.15500  187.44600 1.000 12.33000 ? 229 GLU B N   1 
ATOM   3830 C CA  . GLU B 1 229 ? 34.23900 -2.98000  188.79400 1.000 12.29000 ? 229 GLU B CA  1 
ATOM   3831 C C   . GLU B 1 229 ? 33.34500 -1.75200  188.84200 1.000 10.80000 ? 229 GLU B C   1 
ATOM   3832 O O   . GLU B 1 229 ? 33.54900 -0.79400  188.09600 1.000 15.45000 ? 229 GLU B O   1 
ATOM   3833 C CB  . GLU B 1 229 ? 35.35600 -2.81700  189.84600 1.000 15.44000 ? 229 GLU B CB  1 
ATOM   3834 C CG  . GLU B 1 229 ? 36.36100 -3.96000  189.89300 1.000 20.97000 ? 229 GLU B CG  1 
ATOM   3835 C CD  . GLU B 1 229 ? 35.76500 -5.27200  190.38900 1.000 20.85000 ? 229 GLU B CD  1 
ATOM   3836 O OE1 . GLU B 1 229 ? 34.72400 -5.26000  191.09700 1.000 22.14000 ? 229 GLU B OE1 1 
ATOM   3837 O OE2 . GLU B 1 229 ? 36.35400 -6.32200  190.06800 1.000 27.14000 ? 229 GLU B OE2 1 
ATOM   3838 N N   . GLY B 1 230 ? 32.36200 -1.78100  189.74700 1.000 13.32000 ? 230 GLY B N   1 
ATOM   3839 C CA  . GLY B 1 230 ? 31.54500 -0.61900  190.04300 1.000 12.81000 ? 230 GLY B CA  1 
ATOM   3840 C C   . GLY B 1 230 ? 30.30200 -0.47700  189.19600 1.000 14.34000 ? 230 GLY B C   1 
ATOM   3841 O O   . GLY B 1 230 ? 29.47200 0.40200   189.46500 1.000 12.97000 ? 230 GLY B O   1 
ATOM   3842 N N   . TYR B 1 231 ? 30.11400 -1.40500  188.23400 1.000 11.41000 ? 231 TYR B N   1 
ATOM   3843 C CA  . TYR B 1 231 ? 28.98900 -1.34100  187.24800 1.000 10.68000 ? 231 TYR B CA  1 
ATOM   3844 C C   . TYR B 1 231 ? 28.11600 -2.62500  187.22400 1.000 19.52000 ? 231 TYR B C   1 
ATOM   3845 O O   . TYR B 1 231 ? 27.70500 -3.02400  186.12400 1.000 32.86000 ? 231 TYR B O   1 
ATOM   3846 C CB  . TYR B 1 231 ? 29.52200 -1.00400  185.85500 1.000 10.84000 ? 231 TYR B CB  1 
ATOM   3847 C CG  . TYR B 1 231 ? 30.18400 0.36100   185.78900 1.000 11.05000 ? 231 TYR B CG  1 
ATOM   3848 C CD1 . TYR B 1 231 ? 29.42600 1.51800   185.70900 1.000 9.27000  ? 231 TYR B CD1 1 
ATOM   3849 C CD2 . TYR B 1 231 ? 31.56400 0.48900   185.85100 1.000 13.64000 ? 231 TYR B CD2 1 
ATOM   3850 C CE1 . TYR B 1 231 ? 30.02400 2.76500   185.66900 1.000 12.05000 ? 231 TYR B CE1 1 
ATOM   3851 C CE2 . TYR B 1 231 ? 32.17300 1.72900   185.80900 1.000 15.17000 ? 231 TYR B CE2 1 
ATOM   3852 C CZ  . TYR B 1 231 ? 31.40000 2.87100   185.71300 1.000 15.21000 ? 231 TYR B CZ  1 
ATOM   3853 O OH  . TYR B 1 231 ? 31.98700 4.09700   185.67500 1.000 14.92000 ? 231 TYR B OH  1 
ATOM   3854 N N   . LEU B 1 232 ? 27.80900 -3.19500  188.38200 1.000 33.80000 ? 232 LEU B N   1 
ATOM   3855 C CA  . LEU B 1 232 ? 26.86200 -4.34600  188.45600 1.000 14.95000 ? 232 LEU B CA  1 
ATOM   3856 C C   . LEU B 1 232 ? 27.52800 -5.64600  187.96600 1.000 15.82000 ? 232 LEU B C   1 
ATOM   3857 O O   . LEU B 1 232 ? 27.72600 -6.49700  188.83300 1.000 14.72000 ? 232 LEU B O   1 
ATOM   3858 C CB  . LEU B 1 232 ? 25.53000 -4.09600  187.75300 1.000 19.30000 ? 232 LEU B CB  1 
ATOM   3859 C CG  . LEU B 1 232 ? 24.43200 -3.38600  188.54700 1.000 22.72000 ? 232 LEU B CG  1 
ATOM   3860 C CD1 . LEU B 1 232 ? 23.11400 -3.69600  187.87300 1.000 20.89000 ? 232 LEU B CD1 1 
ATOM   3861 C CD2 . LEU B 1 232 ? 24.40500 -3.81600  189.99900 1.000 25.20000 ? 232 LEU B CD2 1 
ATOM   3862 N N   . LEU B 1 233 ? 27.81600 -5.79200  186.67400 1.000 9.95000  ? 233 LEU B N   1 
ATOM   3863 C CA  . LEU B 1 233 ? 28.52900 -6.99900  186.29500 1.000 10.02000 ? 233 LEU B CA  1 
ATOM   3864 C C   . LEU B 1 233 ? 30.01300 -6.77100  186.54300 1.000 10.79000 ? 233 LEU B C   1 
ATOM   3865 O O   . LEU B 1 233 ? 30.59400 -5.83900  185.98000 1.000 11.96000 ? 233 LEU B O   1 
ATOM   3866 C CB  . LEU B 1 233 ? 28.25100 -7.29200  184.82200 1.000 9.12000  ? 233 LEU B CB  1 
ATOM   3867 C CG  . LEU B 1 233 ? 28.99500 -8.44400  184.16100 1.000 7.48000  ? 233 LEU B CG  1 
ATOM   3868 C CD1 . LEU B 1 233 ? 28.63600 -9.75800  184.83300 1.000 11.06000 ? 233 LEU B CD1 1 
ATOM   3869 C CD2 . LEU B 1 233 ? 28.68500 -8.47400  182.64800 1.000 7.53000  ? 233 LEU B CD2 1 
ATOM   3870 N N   . THR B 1 234 ? 30.62100 -7.60100  187.38700 1.000 11.99000 ? 234 THR B N   1 
ATOM   3871 C CA  . THR B 1 234 ? 32.00700 -7.40500  187.79000 1.000 16.33000 ? 234 THR B CA  1 
ATOM   3872 C C   . THR B 1 234 ? 32.90400 -8.49400  187.21900 1.000 17.68000 ? 234 THR B C   1 
ATOM   3873 O O   . THR B 1 234 ? 32.43800 -9.54500  186.76800 1.000 14.43000 ? 234 THR B O   1 
ATOM   3874 C CB  . THR B 1 234 ? 32.15600 -7.40000  189.31400 1.000 16.42000 ? 234 THR B CB  1 
ATOM   3875 O OG1 . THR B 1 234 ? 31.79000 -8.68900  189.82900 1.000 16.17000 ? 234 THR B OG1 1 
ATOM   3876 C CG2 . THR B 1 234 ? 31.27500 -6.32400  189.94800 1.000 16.46000 ? 234 THR B CG2 1 
ATOM   3877 N N   . ALA B 1 235 ? 34.21300 -8.22700  187.27300 1.000 15.51000 ? 235 ALA B N   1 
ATOM   3878 C CA  . ALA B 1 235 ? 35.19700 -9.22900  186.87300 1.000 21.54000 ? 235 ALA B CA  1 
ATOM   3879 C C   . ALA B 1 235 ? 35.08000 -10.49300 187.71600 1.000 17.66000 ? 235 ALA B C   1 
ATOM   3880 O O   . ALA B 1 235 ? 35.25100 -11.60600 187.20000 1.000 19.74000 ? 235 ALA B O   1 
ATOM   3881 C CB  . ALA B 1 235 ? 36.61000 -8.65000  186.96900 1.000 24.25000 ? 235 ALA B CB  1 
ATOM   3882 N N   . GLU B 1 236 ? 34.80400 -10.34500 189.01600 1.000 17.64000 ? 236 GLU B N   1 
ATOM   3883 C CA  . GLU B 1 236 ? 34.65000 -11.51600 189.87900 1.000 18.24000 ? 236 GLU B CA  1 
ATOM   3884 C C   . GLU B 1 236 ? 33.46300 -12.35800 189.44400 1.000 18.30000 ? 236 GLU B C   1 
ATOM   3885 O O   . GLU B 1 236 ? 33.53000 -13.59600 189.44100 1.000 13.88000 ? 236 GLU B O   1 
ATOM   3886 C CB  . GLU B 1 236 ? 34.47000 -11.09800 191.34100 1.000 23.00000 ? 236 GLU B CB  1 
ATOM   3887 C CG  . GLU B 1 236 ? 35.74500 -10.69300 192.05900 1.000 28.53000 ? 236 GLU B CG  1 
ATOM   3888 C CD  . GLU B 1 236 ? 36.20700 -9.30200  191.66800 1.000 34.72000 ? 236 GLU B CD  1 
ATOM   3889 O OE1 . GLU B 1 236 ? 35.38700 -8.53500  191.10800 1.000 26.41000 ? 236 GLU B OE1 1 
ATOM   3890 O OE2 . GLU B 1 236 ? 37.38800 -8.97700  191.91900 1.000 40.15000 ? 236 GLU B OE2 1 
ATOM   3891 N N   . THR B 1 237 ? 32.36000 -11.70300 189.08600 1.000 14.53000 ? 237 THR B N   1 
ATOM   3892 C CA  . THR B 1 237 ? 31.19500 -12.44500 188.62200 1.000 13.76000 ? 237 THR B CA  1 
ATOM   3893 C C   . THR B 1 237 ? 31.48500 -13.15200 187.30200 1.000 11.37000 ? 237 THR B C   1 
ATOM   3894 O O   . THR B 1 237 ? 31.11500 -14.31900 187.13100 1.000 11.19000 ? 237 THR B O   1 
ATOM   3895 C CB  . THR B 1 237 ? 29.99900 -11.50300 188.50600 1.000 15.91000 ? 237 THR B CB  1 
ATOM   3896 O OG1 . THR B 1 237 ? 29.64200 -11.04600 189.81900 1.000 16.74000 ? 237 THR B OG1 1 
ATOM   3897 C CG2 . THR B 1 237 ? 28.81100 -12.22500 187.90900 1.000 14.58000 ? 237 THR B CG2 1 
ATOM   3898 N N   . MET B 1 238 ? 32.15400 -12.46500 186.36600 1.000 10.25000 ? 238 MET B N   1 
ATOM   3899 C CA  . MET B 1 238 ? 32.51400 -13.08500 185.09100 1.000 12.43000 ? 238 MET B CA  1 
ATOM   3900 C C   . MET B 1 238 ? 33.42600 -14.29200 185.30500 1.000 14.37000 ? 238 MET B C   1 
ATOM   3901 O O   . MET B 1 238 ? 33.26300 -15.32700 184.64900 1.000 10.78000 ? 238 MET B O   1 
ATOM   3902 C CB  . MET B 1 238 ? 33.19500 -12.06100 184.16900 1.000 14.82000 ? 238 MET B CB  1 
ATOM   3903 C CG  . MET B 1 238 ? 32.28300 -10.99500 183.50300 1.000 20.31000 ? 238 MET B CG  1 
ATOM   3904 S SD  . MET B 1 238 ? 31.05900 -11.67700 182.35800 1.000 31.52000 ? 238 MET B SD  1 
ATOM   3905 C CE  . MET B 1 238 ? 32.08300 -12.29100 181.01000 1.000 25.02000 ? 238 MET B CE  1 
ATOM   3906 N N   . ALA B 1 239 ? 34.39300 -14.17400 186.22300 1.000 12.25000 ? 239 ALA B N   1 
ATOM   3907 C CA  . ALA B 1 239 ? 35.29000 -15.28800 186.51800 1.000 12.26000 ? 239 ALA B CA  1 
ATOM   3908 C C   . ALA B 1 239 ? 34.53100 -16.46100 187.12200 1.000 10.80000 ? 239 ALA B C   1 
ATOM   3909 O O   . ALA B 1 239 ? 34.79800 -17.62200 186.78400 1.000 11.06000 ? 239 ALA B O   1 
ATOM   3910 C CB  . ALA B 1 239 ? 36.40400 -14.82900 187.46500 1.000 14.63000 ? 239 ALA B CB  1 
ATOM   3911 N N   . PHE B 1 240 ? 33.59200 -16.16900 188.02600 1.000 7.80000  ? 240 PHE B N   1 
ATOM   3912 C CA  . PHE B 1 240 ? 32.74200 -17.19600 188.62100 1.000 9.24000  ? 240 PHE B CA  1 
ATOM   3913 C C   . PHE B 1 240 ? 31.96300 -17.95700 187.54900 1.000 10.32000 ? 240 PHE B C   1 
ATOM   3914 O O   . PHE B 1 240 ? 31.96800 -19.19400 187.52400 1.000 9.79000  ? 240 PHE B O   1 
ATOM   3915 C CB  . PHE B 1 240 ? 31.80600 -16.53200 189.63700 1.000 13.18000 ? 240 PHE B CB  1 
ATOM   3916 C CG  . PHE B 1 240 ? 30.65500 -17.38900 190.09000 1.000 12.63000 ? 240 PHE B CG  1 
ATOM   3917 C CD1 . PHE B 1 240 ? 30.86700 -18.49900 190.89100 1.000 12.78000 ? 240 PHE B CD1 1 
ATOM   3918 C CD2 . PHE B 1 240 ? 29.35500 -17.04300 189.76300 1.000 13.12000 ? 240 PHE B CD2 1 
ATOM   3919 C CE1 . PHE B 1 240 ? 29.80800 -19.26700 191.32900 1.000 14.13000 ? 240 PHE B CE1 1 
ATOM   3920 C CE2 . PHE B 1 240 ? 28.28600 -17.80700 190.19200 1.000 10.19000 ? 240 PHE B CE2 1 
ATOM   3921 C CZ  . PHE B 1 240 ? 28.51200 -18.92300 190.97800 1.000 13.04000 ? 240 PHE B CZ  1 
ATOM   3922 N N   . PHE B 1 241 ? 31.30000 -17.23000 186.64200 1.000 8.27000  ? 241 PHE B N   1 
ATOM   3923 C CA  . PHE B 1 241 ? 30.58000 -17.88300 185.55100 1.000 7.38000  ? 241 PHE B CA  1 
ATOM   3924 C C   . PHE B 1 241 ? 31.51700 -18.71700 184.68300 1.000 8.26000  ? 241 PHE B C   1 
ATOM   3925 O O   . PHE B 1 241 ? 31.17700 -19.83400 184.27700 1.000 7.72000  ? 241 PHE B O   1 
ATOM   3926 C CB  . PHE B 1 241 ? 29.88500 -16.84200 184.66900 1.000 7.77000  ? 241 PHE B CB  1 
ATOM   3927 C CG  . PHE B 1 241 ? 28.75600 -16.10500 185.33800 1.000 8.84000  ? 241 PHE B CG  1 
ATOM   3928 C CD1 . PHE B 1 241 ? 28.01900 -16.68300 186.35600 1.000 8.59000  ? 241 PHE B CD1 1 
ATOM   3929 C CD2 . PHE B 1 241 ? 28.41100 -14.82600 184.89600 1.000 11.02000 ? 241 PHE B CD2 1 
ATOM   3930 C CE1 . PHE B 1 241 ? 26.95500 -15.98700 186.94300 1.000 9.79000  ? 241 PHE B CE1 1 
ATOM   3931 C CE2 . PHE B 1 241 ? 27.35500 -14.13500 185.46300 1.000 10.57000 ? 241 PHE B CE2 1 
ATOM   3932 C CZ  . PHE B 1 241 ? 26.62800 -14.70700 186.48900 1.000 10.03000 ? 241 PHE B CZ  1 
ATOM   3933 N N   . ASP B 1 242 ? 32.69100 -18.17300 184.36100 1.000 6.79000  ? 242 ASP B N   1 
ATOM   3934 C CA  . ASP B 1 242 ? 33.60300 -18.84900 183.44600 1.000 9.10000  ? 242 ASP B CA  1 
ATOM   3935 C C   . ASP B 1 242 ? 34.09800 -20.16500 184.03600 1.000 9.04000  ? 242 ASP B C   1 
ATOM   3936 O O   . ASP B 1 242 ? 34.21700 -21.17200 183.32500 1.000 7.76000  ? 242 ASP B O   1 
ATOM   3937 C CB  . ASP B 1 242 ? 34.78200 -17.92800 183.13500 1.000 8.86000  ? 242 ASP B CB  1 
ATOM   3938 C CG  . ASP B 1 242 ? 35.56700 -18.37000 181.91500 1.000 14.01000 ? 242 ASP B CG  1 
ATOM   3939 O OD1 . ASP B 1 242 ? 34.94200 -18.76300 180.90200 1.000 19.38000 ? 242 ASP B OD1 1 
ATOM   3940 O OD2 . ASP B 1 242 ? 36.81800 -18.30500 181.96700 1.000 18.01000 ? 242 ASP B OD2 1 
ATOM   3941 N N   . ALA B 1 243 ? 34.41500 -20.17000 185.33200 1.000 8.52000  ? 243 ALA B N   1 
ATOM   3942 C CA  . ALA B 1 243 ? 34.94500 -21.37600 185.95900 1.000 6.25000  ? 243 ALA B CA  1 
ATOM   3943 C C   . ALA B 1 243 ? 33.87700 -22.44400 186.15400 1.000 10.32000 ? 243 ALA B C   1 
ATOM   3944 O O   . ALA B 1 243 ? 34.22100 -23.61200 186.38400 1.000 9.59000  ? 243 ALA B O   1 
ATOM   3945 C CB  . ALA B 1 243 ? 35.60000 -21.02400 187.29600 1.000 8.57000  ? 243 ALA B CB  1 
ATOM   3946 N N   . ALA B 1 244 ? 32.59500 -22.07700 186.06600 1.000 7.84000  ? 244 ALA B N   1 
ATOM   3947 C CA  . ALA B 1 244 ? 31.50600 -23.04200 186.18000 1.000 7.78000  ? 244 ALA B CA  1 
ATOM   3948 C C   . ALA B 1 244 ? 31.09000 -23.59900 184.82200 1.000 8.06000  ? 244 ALA B C   1 
ATOM   3949 O O   . ALA B 1 244 ? 30.92300 -24.81200 184.67000 1.000 7.31000  ? 244 ALA B O   1 
ATOM   3950 C CB  . ALA B 1 244 ? 30.30000 -22.39600 186.87000 1.000 7.24000  ? 244 ALA B CB  1 
ATOM   3951 N N   . TYR B 1 245 ? 30.92500 -22.71900 183.82700 1.000 7.76000  ? 245 TYR B N   1 
ATOM   3952 C CA  . TYR B 1 245 ? 30.45800 -23.12900 182.50600 1.000 6.95000  ? 245 TYR B CA  1 
ATOM   3953 C C   . TYR B 1 245 ? 31.57600 -23.72900 181.65900 1.000 7.85000  ? 245 TYR B C   1 
ATOM   3954 O O   . TYR B 1 245 ? 31.37900 -24.75300 180.99400 1.000 6.36000  ? 245 TYR B O   1 
ATOM   3955 C CB  . TYR B 1 245 ? 29.84200 -21.92000 181.80500 1.000 5.86000  ? 245 TYR B CB  1 
ATOM   3956 C CG  . TYR B 1 245 ? 29.12200 -22.19800 180.50400 1.000 8.98000  ? 245 TYR B CG  1 
ATOM   3957 C CD1 . TYR B 1 245 ? 28.03100 -23.06100 180.45200 1.000 6.44000  ? 245 TYR B CD1 1 
ATOM   3958 C CD2 . TYR B 1 245 ? 29.50400 -21.54800 179.33400 1.000 7.14000  ? 245 TYR B CD2 1 
ATOM   3959 C CE1 . TYR B 1 245 ? 27.34900 -23.28600 179.26200 1.000 7.21000  ? 245 TYR B CE1 1 
ATOM   3960 C CE2 . TYR B 1 245 ? 28.83500 -21.76600 178.14700 1.000 7.40000  ? 245 TYR B CE2 1 
ATOM   3961 C CZ  . TYR B 1 245 ? 27.75700 -22.63300 178.11800 1.000 7.61000  ? 245 TYR B CZ  1 
ATOM   3962 O OH  . TYR B 1 245 ? 27.07900 -22.83200 176.93300 1.000 7.32000  ? 245 TYR B OH  1 
ATOM   3963 N N   . GLY B 1 246 ? 32.74700 -23.08900 181.64600 1.000 6.52000  ? 246 GLY B N   1 
ATOM   3964 C CA  . GLY B 1 246 ? 33.90600 -23.61900 180.95000 1.000 6.50000  ? 246 GLY B CA  1 
ATOM   3965 C C   . GLY B 1 246 ? 33.74100 -23.74500 179.44600 1.000 6.03000  ? 246 GLY B C   1 
ATOM   3966 O O   . GLY B 1 246 ? 33.99600 -24.81000 178.88100 1.000 9.34000  ? 246 GLY B O   1 
ATOM   3967 N N   . ALA B 1 247 ? 33.33700 -22.66300 178.78400 1.000 6.21000  ? 247 ALA B N   1 
ATOM   3968 C CA  . ALA B 1 247 ? 33.16900 -22.69700 177.33600 1.000 6.66000  ? 247 ALA B CA  1 
ATOM   3969 C C   . ALA B 1 247 ? 34.50900 -22.89800 176.63400 1.000 10.02000 ? 247 ALA B C   1 
ATOM   3970 O O   . ALA B 1 247 ? 35.53300 -22.33000 177.02800 1.000 10.30000 ? 247 ALA B O   1 
ATOM   3971 C CB  . ALA B 1 247 ? 32.51200 -21.40200 176.84600 1.000 7.87000  ? 247 ALA B CB  1 
ATOM   3972 N N   . ASP B 1 248 ? 34.48800 -23.70700 175.57700 1.000 9.17000  ? 248 ASP B N   1 
ATOM   3973 C CA  . ASP B 1 248 ? 35.65600 -23.94700 174.73200 1.000 11.29000 ? 248 ASP B CA  1 
ATOM   3974 C C   . ASP B 1 248 ? 35.90200 -22.72400 173.85300 1.000 12.33000 ? 248 ASP B C   1 
ATOM   3975 O O   . ASP B 1 248 ? 35.04600 -22.35300 173.04000 1.000 10.97000 ? 248 ASP B O   1 
ATOM   3976 C CB  . ASP B 1 248 ? 35.41000 -25.21100 173.90600 1.000 11.51000 ? 248 ASP B CB  1 
ATOM   3977 C CG  . ASP B 1 248 ? 36.53200 -25.52700 172.90300 1.000 15.20000 ? 248 ASP B CG  1 
ATOM   3978 O OD1 . ASP B 1 248 ? 37.51700 -24.76800 172.76100 1.000 15.24000 ? 248 ASP B OD1 1 
ATOM   3979 O OD2 . ASP B 1 248 ? 36.39800 -26.58000 172.24300 1.000 18.59000 ? 248 ASP B OD2 1 
ATOM   3980 N N   . ARG B 1 249 ? 37.07600 -22.10400 174.01100 1.000 11.68000 ? 249 ARG B N   1 
ATOM   3981 C CA  . ARG B 1 249 ? 37.40200 -20.86800 173.30400 1.000 12.65000 ? 249 ARG B CA  1 
ATOM   3982 C C   . ARG B 1 249 ? 37.51200 -21.05400 171.79400 1.000 14.11000 ? 249 ARG B C   1 
ATOM   3983 O O   . ARG B 1 249 ? 37.47600 -20.06200 171.05500 1.000 10.99000 ? 249 ARG B O   1 
ATOM   3984 C CB  . ARG B 1 249 ? 38.70900 -20.29300 173.85000 1.000 16.39000 ? 249 ARG B CB  1 
ATOM   3985 C CG  . ARG B 1 249 ? 38.53000 -19.12300 174.81100 1.000 18.63000 ? 249 ARG B CG  1 
ATOM   3986 C CD  . ARG B 1 249 ? 37.83700 -19.52500 176.09800 1.000 22.08000 ? 249 ARG B CD  1 
ATOM   3987 N NE  . ARG B 1 249 ? 37.48400 -18.33300 176.86900 1.000 30.34000 ? 249 ARG B NE  1 
ATOM   3988 C CZ  . ARG B 1 249 ? 36.78200 -18.33400 178.00100 1.000 29.93000 ? 249 ARG B CZ  1 
ATOM   3989 N NH1 . ARG B 1 249 ? 36.34300 -19.47700 178.52400 1.000 22.18000 ? 249 ARG B NH1 1 
ATOM   3990 N NH2 . ARG B 1 249 ? 36.51500 -17.18000 178.60700 1.000 26.58000 ? 249 ARG B NH2 1 
ATOM   3991 N N   . SER B 1 250 ? 37.64800 -22.28800 171.31800 1.000 11.10000 ? 250 SER B N   1 
ATOM   3992 C CA  . SER B 1 250 ? 37.75000 -22.58000 169.89500 1.000 12.88000 ? 250 SER B CA  1 
ATOM   3993 C C   . SER B 1 250 ? 36.42700 -23.00800 169.27500 1.000 13.18000 ? 250 SER B C   1 
ATOM   3994 O O   . SER B 1 250 ? 36.37800 -23.28700 168.06900 1.000 13.89000 ? 250 SER B O   1 
ATOM   3995 C CB  . SER B 1 250 ? 38.79700 -23.67800 169.67200 1.000 19.30000 ? 250 SER B CB  1 
ATOM   3996 O OG  . SER B 1 250 ? 40.10100 -23.13700 169.77400 1.000 30.35000 ? 250 SER B OG  1 
ATOM   3997 N N   . ASP B 1 251 ? 35.36000 -23.07400 170.06500 1.000 9.61000  ? 251 ASP B N   1 
ATOM   3998 C CA  . ASP B 1 251 ? 34.09500 -23.64800 169.64200 1.000 10.45000 ? 251 ASP B CA  1 
ATOM   3999 C C   . ASP B 1 251 ? 33.11300 -22.52300 169.35800 1.000 9.26000  ? 251 ASP B C   1 
ATOM   4000 O O   . ASP B 1 251 ? 32.86800 -21.70500 170.25900 1.000 9.86000  ? 251 ASP B O   1 
ATOM   4001 C CB  . ASP B 1 251 ? 33.56100 -24.56300 170.74300 1.000 9.53000  ? 251 ASP B CB  1 
ATOM   4002 C CG  . ASP B 1 251 ? 32.38500 -25.42400 170.30300 1.000 12.52000 ? 251 ASP B CG  1 
ATOM   4003 O OD1 . ASP B 1 251 ? 31.56500 -24.98400 169.46300 1.000 11.26000 ? 251 ASP B OD1 1 
ATOM   4004 O OD2 . ASP B 1 251 ? 32.26600 -26.54900 170.83700 1.000 14.98000 ? 251 ASP B OD2 1 
ATOM   4005 N N   . PRO B 1 252 ? 32.55300 -22.41400 168.14600 1.000 9.59000  ? 252 PRO B N   1 
ATOM   4006 C CA  . PRO B 1 252 ? 31.57000 -21.34800 167.88800 1.000 7.96000  ? 252 PRO B CA  1 
ATOM   4007 C C   . PRO B 1 252 ? 30.32000 -21.46600 168.74100 1.000 8.10000  ? 252 PRO B C   1 
ATOM   4008 O O   . PRO B 1 252 ? 29.57600 -20.48700 168.86200 1.000 8.52000  ? 252 PRO B O   1 
ATOM   4009 C CB  . PRO B 1 252 ? 31.24300 -21.51100 166.39600 1.000 13.71000 ? 252 PRO B CB  1 
ATOM   4010 C CG  . PRO B 1 252 ? 31.68800 -22.90600 166.04300 1.000 17.01000 ? 252 PRO B CG  1 
ATOM   4011 C CD  . PRO B 1 252 ? 32.82400 -23.23600 166.95100 1.000 12.82000 ? 252 PRO B CD  1 
ATOM   4012 N N   . ARG B 1 253 ? 30.06500 -22.62700 169.34900 1.000 7.84000  ? 253 ARG B N   1 
ATOM   4013 C CA  . ARG B 1 253 ? 28.95100 -22.73200 170.28300 1.000 7.92000  ? 253 ARG B CA  1 
ATOM   4014 C C   . ARG B 1 253 ? 29.26400 -22.09100 171.62700 1.000 7.85000  ? 253 ARG B C   1 
ATOM   4015 O O   . ARG B 1 253 ? 28.33800 -21.83300 172.40600 1.000 8.33000  ? 253 ARG B O   1 
ATOM   4016 C CB  . ARG B 1 253 ? 28.56400 -24.19800 170.48000 1.000 8.98000  ? 253 ARG B CB  1 
ATOM   4017 C CG  . ARG B 1 253 ? 28.06000 -24.86400 169.20100 1.000 10.57000 ? 253 ARG B CG  1 
ATOM   4018 C CD  . ARG B 1 253 ? 27.86800 -26.36300 169.40700 1.000 10.91000 ? 253 ARG B CD  1 
ATOM   4019 N NE  . ARG B 1 253 ? 29.06800 -26.97800 169.97400 1.000 13.58000 ? 253 ARG B NE  1 
ATOM   4020 C CZ  . ARG B 1 253 ? 29.09800 -28.18400 170.53900 1.000 16.50000 ? 253 ARG B CZ  1 
ATOM   4021 N NH1 . ARG B 1 253 ? 30.24200 -28.65400 171.03600 1.000 13.50000 ? 253 ARG B NH1 1 
ATOM   4022 N NH2 . ARG B 1 253 ? 27.98800 -28.92100 170.61400 1.000 14.36000 ? 253 ARG B NH2 1 
ATOM   4023 N N   . GLY B 1 254 ? 30.53900 -21.83900 171.91400 1.000 7.23000  ? 254 GLY B N   1 
ATOM   4024 C CA  . GLY B 1 254 ? 30.92700 -21.06400 173.07100 1.000 6.32000  ? 254 GLY B CA  1 
ATOM   4025 C C   . GLY B 1 254 ? 31.05500 -19.59500 172.72200 1.000 7.91000  ? 254 GLY B C   1 
ATOM   4026 O O   . GLY B 1 254 ? 30.61900 -18.73000 173.48600 1.000 7.60000  ? 254 GLY B O   1 
ATOM   4027 N N   . PHE B 1 255 ? 31.65500 -19.30300 171.56500 1.000 6.65000  ? 255 PHE B N   1 
ATOM   4028 C CA  . PHE B 1 255 ? 31.94600 -17.93300 171.14500 1.000 6.34000  ? 255 PHE B CA  1 
ATOM   4029 C C   . PHE B 1 255 ? 31.52200 -17.79000 169.69000 1.000 6.47000  ? 255 PHE B C   1 
ATOM   4030 O O   . PHE B 1 255 ? 32.32300 -18.00300 168.77200 1.000 7.76000  ? 255 PHE B O   1 
ATOM   4031 C CB  . PHE B 1 255 ? 33.42000 -17.61100 171.38300 1.000 9.85000  ? 255 PHE B CB  1 
ATOM   4032 C CG  . PHE B 1 255 ? 33.79900 -17.74500 172.81800 1.000 10.87000 ? 255 PHE B CG  1 
ATOM   4033 C CD1 . PHE B 1 255 ? 33.61500 -16.68500 173.69000 1.000 11.83000 ? 255 PHE B CD1 1 
ATOM   4034 C CD2 . PHE B 1 255 ? 34.23200 -18.96500 173.32100 1.000 10.98000 ? 255 PHE B CD2 1 
ATOM   4035 C CE1 . PHE B 1 255 ? 33.91100 -16.82200 175.03900 1.000 13.85000 ? 255 PHE B CE1 1 
ATOM   4036 C CE2 . PHE B 1 255 ? 34.53000 -19.11700 174.67000 1.000 14.07000 ? 255 PHE B CE2 1 
ATOM   4037 C CZ  . PHE B 1 255 ? 34.37300 -18.04300 175.53000 1.000 15.62000 ? 255 PHE B CZ  1 
ATOM   4038 N N   . PRO B 1 256 ? 30.25300 -17.44100 169.44400 1.000 8.43000  ? 256 PRO B N   1 
ATOM   4039 C CA  . PRO B 1 256 ? 29.72100 -17.47300 168.07100 1.000 6.79000  ? 256 PRO B CA  1 
ATOM   4040 C C   . PRO B 1 256 ? 30.28200 -16.39800 167.16000 1.000 7.15000  ? 256 PRO B C   1 
ATOM   4041 O O   . PRO B 1 256 ? 29.96600 -16.40000 165.96900 1.000 6.85000  ? 256 PRO B O   1 
ATOM   4042 C CB  . PRO B 1 256 ? 28.20800 -17.30300 168.27300 1.000 7.15000  ? 256 PRO B CB  1 
ATOM   4043 C CG  . PRO B 1 256 ? 28.05700 -16.64900 169.62900 1.000 6.83000  ? 256 PRO B CG  1 
ATOM   4044 C CD  . PRO B 1 256 ? 29.19800 -17.21000 170.44900 1.000 6.87000  ? 256 PRO B CD  1 
ATOM   4045 N N   . ILE B 1 257 ? 31.14100 -15.50400 167.65600 1.000 5.77000  ? 257 ILE B N   1 
ATOM   4046 C CA  . ILE B 1 257 ? 31.88900 -14.65500 166.73600 1.000 7.45000  ? 257 ILE B CA  1 
ATOM   4047 C C   . ILE B 1 257 ? 32.67400 -15.51300 165.75100 1.000 8.53000  ? 257 ILE B C   1 
ATOM   4048 O O   . ILE B 1 257 ? 32.96400 -15.08100 164.62800 1.000 9.56000  ? 257 ILE B O   1 
ATOM   4049 C CB  . ILE B 1 257 ? 32.80500 -13.68400 167.51300 1.000 8.05000  ? 257 ILE B CB  1 
ATOM   4050 C CG1 . ILE B 1 257 ? 33.22600 -12.52000 166.60800 1.000 10.91000 ? 257 ILE B CG1 1 
ATOM   4051 C CG2 . ILE B 1 257 ? 34.02300 -14.41800 168.08600 1.000 8.52000  ? 257 ILE B CG2 1 
ATOM   4052 C CD1 . ILE B 1 257 ? 32.10600 -11.54000 166.32000 1.000 9.95000  ? 257 ILE B CD1 1 
ATOM   4053 N N   . LEU B 1 258 ? 32.99300 -16.75500 166.13500 1.000 10.12000 ? 258 LEU B N   1 
ATOM   4054 C CA  . LEU B 1 258 ? 33.73500 -17.68900 165.29800 1.000 8.49000  ? 258 LEU B CA  1 
ATOM   4055 C C   . LEU B 1 258 ? 32.86000 -18.40400 164.27900 1.000 12.58000 ? 258 LEU B C   1 
ATOM   4056 O O   . LEU B 1 258 ? 33.39000 -19.13200 163.43000 1.000 11.72000 ? 258 LEU B O   1 
ATOM   4057 C CB  . LEU B 1 258 ? 34.42300 -18.73900 166.18100 1.000 7.73000  ? 258 LEU B CB  1 
ATOM   4058 C CG  . LEU B 1 258 ? 35.30200 -18.26000 167.33700 1.000 9.62000  ? 258 LEU B CG  1 
ATOM   4059 C CD1 . LEU B 1 258 ? 35.70900 -19.44500 168.19600 1.000 10.30000 ? 258 LEU B CD1 1 
ATOM   4060 C CD2 . LEU B 1 258 ? 36.52900 -17.54800 166.79400 1.000 14.72000 ? 258 LEU B CD2 1 
ATOM   4061 N N   . GLY B 1 259 ? 31.54100 -18.22800 164.34200 1.000 9.09000  ? 259 GLY B N   1 
ATOM   4062 C CA  . GLY B 1 259 ? 30.63400 -18.96500 163.49000 1.000 10.29000 ? 259 GLY B CA  1 
ATOM   4063 C C   . GLY B 1 259 ? 30.42200 -18.29200 162.14900 1.000 9.71000  ? 259 GLY B C   1 
ATOM   4064 O O   . GLY B 1 259 ? 31.02400 -17.27300 161.81900 1.000 11.76000 ? 259 GLY B O   1 
ATOM   4065 N N   . ARG B 1 260 ? 29.53400 -18.89300 161.36200 1.000 8.61000  ? 260 ARG B N   1 
ATOM   4066 C CA  . ARG B 1 260 ? 29.20900 -18.36800 160.04100 1.000 8.43000  ? 260 ARG B CA  1 
ATOM   4067 C C   . ARG B 1 260 ? 28.24500 -17.19100 160.15700 1.000 9.00000  ? 260 ARG B C   1 
ATOM   4068 O O   . ARG B 1 260 ? 27.23400 -17.27700 160.86300 1.000 9.17000  ? 260 ARG B O   1 
ATOM   4069 C CB  . ARG B 1 260 ? 28.59200 -19.47800 159.19200 1.000 8.35000  ? 260 ARG B CB  1 
ATOM   4070 C CG  . ARG B 1 260 ? 28.21900 -19.03600 157.80800 1.000 12.86000 ? 260 ARG B CG  1 
ATOM   4071 C CD  . ARG B 1 260 ? 27.79100 -20.21400 156.92500 1.000 14.08000 ? 260 ARG B CD  1 
ATOM   4072 N NE  . ARG B 1 260 ? 27.27700 -19.71000 155.65900 1.000 18.21000 ? 260 ARG B NE  1 
ATOM   4073 C CZ  . ARG B 1 260 ? 26.62900 -20.43800 154.75400 1.000 22.38000 ? 260 ARG B CZ  1 
ATOM   4074 N NH1 . ARG B 1 260 ? 26.40200 -21.73100 154.96200 1.000 19.70000 ? 260 ARG B NH1 1 
ATOM   4075 N NH2 . ARG B 1 260 ? 26.19500 -19.85900 153.64200 1.000 20.50000 ? 260 ARG B NH2 1 
ATOM   4076 N N   . HIS B 1 261 ? 28.54700 -16.08900 159.45500 1.000 7.57000  ? 261 HIS B N   1 
ATOM   4077 C CA  . HIS B 1 261 ? 27.72600 -14.88800 159.54400 1.000 7.28000  ? 261 HIS B CA  1 
ATOM   4078 C C   . HIS B 1 261 ? 27.02600 -14.50800 158.24600 1.000 9.31000  ? 261 HIS B C   1 
ATOM   4079 O O   . HIS B 1 261 ? 26.07500 -13.72800 158.29100 1.000 9.43000  ? 261 HIS B O   1 
ATOM   4080 C CB  . HIS B 1 261 ? 28.57800 -13.70100 160.01500 1.000 7.94000  ? 261 HIS B CB  1 
ATOM   4081 C CG  . HIS B 1 261 ? 29.31100 -13.96200 161.29800 1.000 8.60000  ? 261 HIS B CG  1 
ATOM   4082 N ND1 . HIS B 1 261 ? 28.67800 -14.40100 162.44300 1.000 7.96000  ? 261 HIS B ND1 1 
ATOM   4083 C CD2 . HIS B 1 261 ? 30.62500 -13.85700 161.61100 1.000 8.67000  ? 261 HIS B CD2 1 
ATOM   4084 C CE1 . HIS B 1 261 ? 29.57000 -14.54400 163.40800 1.000 8.49000  ? 261 HIS B CE1 1 
ATOM   4085 N NE2 . HIS B 1 261 ? 30.75800 -14.21900 162.93000 1.000 8.95000  ? 261 HIS B NE2 1 
ATOM   4086 N N   . ASP B 1 262 ? 27.44000 -15.06100 157.10400 1.000 9.10000  ? 262 ASP B N   1 
ATOM   4087 C CA  . ASP B 1 262 ? 26.91400 -14.61000 155.81500 1.000 9.85000  ? 262 ASP B CA  1 
ATOM   4088 C C   . ASP B 1 262 ? 25.46900 -15.03300 155.56600 1.000 10.55000 ? 262 ASP B C   1 
ATOM   4089 O O   . ASP B 1 262 ? 24.86600 -14.56200 154.59600 1.000 11.60000 ? 262 ASP B O   1 
ATOM   4090 C CB  . ASP B 1 262 ? 27.78300 -15.14600 154.68200 1.000 12.72000 ? 262 ASP B CB  1 
ATOM   4091 C CG  . ASP B 1 262 ? 27.62400 -16.63700 154.50900 1.000 18.49000 ? 262 ASP B CG  1 
ATOM   4092 O OD1 . ASP B 1 262 ? 28.30100 -17.38900 155.23200 1.000 26.02000 ? 262 ASP B OD1 1 
ATOM   4093 O OD2 . ASP B 1 262 ? 26.80500 -17.06200 153.66900 1.000 30.97000 ? 262 ASP B OD2 1 
ATOM   4094 N N   . ASN B 1 263 ? 24.90600 -15.92000 156.39000 1.000 7.11000  ? 263 ASN B N   1 
ATOM   4095 C CA  . ASN B 1 263 ? 23.49600 -16.28200 156.29600 1.000 7.02000  ? 263 ASN B CA  1 
ATOM   4096 C C   . ASN B 1 263 ? 22.75400 -15.97900 157.59400 1.000 9.68000  ? 263 ASN B C   1 
ATOM   4097 O O   . ASN B 1 263 ? 21.72100 -16.59500 157.88100 1.000 11.21000 ? 263 ASN B O   1 
ATOM   4098 C CB  . ASN B 1 263 ? 23.33500 -17.75500 155.91100 1.000 12.75000 ? 263 ASN B CB  1 
ATOM   4099 C CG  . ASN B 1 263 ? 23.98300 -18.71200 156.91400 1.000 13.30000 ? 263 ASN B CG  1 
ATOM   4100 O OD1 . ASN B 1 263 ? 24.60600 -18.29500 157.89300 1.000 11.84000 ? 263 ASN B OD1 1 
ATOM   4101 N ND2 . ASN B 1 263 ? 23.82900 -20.00800 156.66500 1.000 12.61000 ? 263 ASN B ND2 1 
ATOM   4102 N N   . ALA B 1 264 ? 23.25100 -15.02900 158.37400 1.000 7.35000  ? 264 ALA B N   1 
ATOM   4103 C CA  . ALA B 1 264 ? 22.64100 -14.72800 159.66000 1.000 7.55000  ? 264 ALA B CA  1 
ATOM   4104 C C   . ALA B 1 264 ? 21.22600 -14.18200 159.47000 1.000 10.16000 ? 264 ALA B C   1 
ATOM   4105 O O   . ALA B 1 264 ? 20.94500 -13.49900 158.48200 1.000 12.78000 ? 264 ALA B O   1 
ATOM   4106 C CB  . ALA B 1 264 ? 23.48500 -13.71000 160.41800 1.000 8.95000  ? 264 ALA B CB  1 
ATOM   4107 N N   . PRO B 1 265 ? 20.32100 -14.44300 160.41200 1.000 9.24000  ? 265 PRO B N   1 
ATOM   4108 C CA  . PRO B 1 265 ? 18.96100 -13.88500 160.31500 1.000 9.73000  ? 265 PRO B CA  1 
ATOM   4109 C C   . PRO B 1 265 ? 18.97800 -12.37800 160.50400 1.000 10.72000 ? 265 PRO B C   1 
ATOM   4110 O O   . PRO B 1 265 ? 19.99700 -11.81300 160.93500 1.000 8.03000  ? 265 PRO B O   1 
ATOM   4111 C CB  . PRO B 1 265 ? 18.19200 -14.57300 161.45900 1.000 10.28000 ? 265 PRO B CB  1 
ATOM   4112 C CG  . PRO B 1 265 ? 19.18400 -15.30100 162.28200 1.000 10.96000 ? 265 PRO B CG  1 
ATOM   4113 C CD  . PRO B 1 265 ? 20.53600 -15.25100 161.62700 1.000 7.92000  ? 265 PRO B CD  1 
ATOM   4114 N N   . PRO B 1 266 ? 17.87400 -11.69400 160.18300 1.000 10.08000 ? 266 PRO B N   1 
ATOM   4115 C CA  . PRO B 1 266 ? 17.74700 -10.27300 160.54700 1.000 9.09000  ? 266 PRO B CA  1 
ATOM   4116 C C   . PRO B 1 266 ? 18.03200 -10.08800 162.02900 1.000 7.70000  ? 266 PRO B C   1 
ATOM   4117 O O   . PRO B 1 266 ? 17.57800 -10.88000 162.85800 1.000 6.17000  ? 266 PRO B O   1 
ATOM   4118 C CB  . PRO B 1 266 ? 16.28700 -9.95100  160.21300 1.000 8.48000  ? 266 PRO B CB  1 
ATOM   4119 C CG  . PRO B 1 266 ? 15.91300 -10.97700 159.15700 1.000 9.60000  ? 266 PRO B CG  1 
ATOM   4120 C CD  . PRO B 1 266 ? 16.64000 -12.21900 159.57300 1.000 9.80000  ? 266 PRO B CD  1 
ATOM   4121 N N   . THR B 1 267 ? 18.81500 -9.05400  162.35800 1.000 5.53000  ? 267 THR B N   1 
ATOM   4122 C CA  . THR B 1 267 ? 19.40100 -8.92800  163.69100 1.000 6.70000  ? 267 THR B CA  1 
ATOM   4123 C C   . THR B 1 267 ? 19.23100 -7.52900  164.26800 1.000 6.56000  ? 267 THR B C   1 
ATOM   4124 O O   . THR B 1 267 ? 19.41800 -6.52400  163.57300 1.000 6.97000  ? 267 THR B O   1 
ATOM   4125 C CB  . THR B 1 267 ? 20.90800 -9.26500  163.67700 1.000 7.36000  ? 267 THR B CB  1 
ATOM   4126 O OG1 . THR B 1 267 ? 21.10600 -10.58400 163.14400 1.000 7.15000  ? 267 THR B OG1 1 
ATOM   4127 C CG2 . THR B 1 267 ? 21.50600 -9.18600  165.08900 1.000 7.13000  ? 267 THR B CG2 1 
ATOM   4128 N N   . ILE B 1 268 ? 18.90500 -7.48300  165.55600 1.000 4.07000  ? 268 ILE B N   1 
ATOM   4129 C CA  . ILE B 1 268 ? 19.03900 -6.29100  166.38600 1.000 5.07000  ? 268 ILE B CA  1 
ATOM   4130 C C   . ILE B 1 268 ? 20.02700 -6.62400  167.49800 1.000 5.76000  ? 268 ILE B C   1 
ATOM   4131 O O   . ILE B 1 268 ? 19.73800 -7.47500  168.34400 1.000 6.89000  ? 268 ILE B O   1 
ATOM   4132 C CB  . ILE B 1 268 ? 17.68800 -5.85600  166.97700 1.000 6.24000  ? 268 ILE B CB  1 
ATOM   4133 C CG1 . ILE B 1 268 ? 16.69300 -5.52300  165.86000 1.000 5.45000  ? 268 ILE B CG1 1 
ATOM   4134 C CG2 . ILE B 1 268 ? 17.85800 -4.69000  167.97500 1.000 6.13000  ? 268 ILE B CG2 1 
ATOM   4135 C CD1 . ILE B 1 268 ? 15.23400 -5.67900  166.28500 1.000 6.22000  ? 268 ILE B CD1 1 
ATOM   4136 N N   . VAL B 1 269 ? 21.18200 -5.95600  167.50600 1.000 4.31000  ? 269 VAL B N   1 
ATOM   4137 C CA  . VAL B 1 269 ? 22.17700 -6.11700  168.57100 1.000 4.20000  ? 269 VAL B CA  1 
ATOM   4138 C C   . VAL B 1 269 ? 22.00600 -4.97500  169.55500 1.000 4.87000  ? 269 VAL B C   1 
ATOM   4139 O O   . VAL B 1 269 ? 22.01800 -3.80700  169.15800 1.000 6.40000  ? 269 VAL B O   1 
ATOM   4140 C CB  . VAL B 1 269 ? 23.61300 -6.12800  168.01200 1.000 5.31000  ? 269 VAL B CB  1 
ATOM   4141 C CG1 . VAL B 1 269 ? 24.62900 -6.09500  169.16900 1.000 8.29000  ? 269 VAL B CG1 1 
ATOM   4142 C CG2 . VAL B 1 269 ? 23.84200 -7.34800  167.13600 1.000 7.80000  ? 269 VAL B CG2 1 
ATOM   4143 N N   . VAL B 1 270 ? 21.84900 -5.29400  170.84000 1.000 4.72000  ? 270 VAL B N   1 
ATOM   4144 C CA  . VAL B 1 270 ? 21.68500 -4.26800  171.86500 1.000 5.39000  ? 270 VAL B CA  1 
ATOM   4145 C C   . VAL B 1 270 ? 22.84600 -4.37100  172.84400 1.000 6.70000  ? 270 VAL B C   1 
ATOM   4146 O O   . VAL B 1 270 ? 23.12000 -5.45500  173.37100 1.000 6.31000  ? 270 VAL B O   1 
ATOM   4147 C CB  . VAL B 1 270 ? 20.34200 -4.41200  172.60300 1.000 5.71000  ? 270 VAL B CB  1 
ATOM   4148 C CG1 . VAL B 1 270 ? 20.16800 -3.29400  173.64000 1.000 6.80000  ? 270 VAL B CG1 1 
ATOM   4149 C CG2 . VAL B 1 270 ? 19.18700 -4.41200  171.60200 1.000 7.28000  ? 270 VAL B CG2 1 
ATOM   4150 N N   . THR B 1 271 ? 23.53100 -3.25500  173.07900 1.000 4.54000  ? 271 THR B N   1 
ATOM   4151 C CA  . THR B 1 271 ? 24.58500 -3.19800  174.08700 1.000 5.73000  ? 271 THR B CA  1 
ATOM   4152 C C   . THR B 1 271 ? 24.27300 -2.09700  175.08700 1.000 6.97000  ? 271 THR B C   1 
ATOM   4153 O O   . THR B 1 271 ? 23.33600 -1.31800  174.91500 1.000 5.75000  ? 271 THR B O   1 
ATOM   4154 C CB  . THR B 1 271 ? 25.96000 -2.95000  173.45400 1.000 5.73000  ? 271 THR B CB  1 
ATOM   4155 O OG1 . THR B 1 271 ? 25.91800 -1.73000  172.69200 1.000 7.01000  ? 271 THR B OG1 1 
ATOM   4156 C CG2 . THR B 1 271 ? 26.35900 -4.11600  172.55000 1.000 6.06000  ? 271 THR B CG2 1 
ATOM   4157 N N   . ALA B 1 272 ? 25.05900 -2.06200  176.16800 1.000 5.14000  ? 272 ALA B N   1 
ATOM   4158 C CA  . ALA B 1 272 ? 24.97500 -1.01100  177.17600 1.000 5.85000  ? 272 ALA B CA  1 
ATOM   4159 C C   . ALA B 1 272 ? 26.33200 -0.33200  177.27900 1.000 7.80000  ? 272 ALA B C   1 
ATOM   4160 O O   . ALA B 1 272 ? 27.36600 -0.99800  177.24700 1.000 6.65000  ? 272 ALA B O   1 
ATOM   4161 C CB  . ALA B 1 272 ? 24.57900 -1.58300  178.53900 1.000 5.84000  ? 272 ALA B CB  1 
ATOM   4162 N N   . SER B 1 273 ? 26.33900 0.99400   177.41100 1.000 6.12000  ? 273 SER B N   1 
ATOM   4163 C CA  . SER B 1 273 ? 27.61300 1.70200   177.30300 1.000 6.68000  ? 273 SER B CA  1 
ATOM   4164 C C   . SER B 1 273 ? 28.51600 1.48800   178.51600 1.000 7.36000  ? 273 SER B C   1 
ATOM   4165 O O   . SER B 1 273 ? 29.74400 1.65800   178.39200 1.000 8.67000  ? 273 SER B O   1 
ATOM   4166 C CB  . SER B 1 273 ? 27.37100 3.20000   177.08500 1.000 7.93000  ? 273 SER B CB  1 
ATOM   4167 O OG  . SER B 1 273 ? 26.89300 3.83700   178.27000 1.000 6.79000  ? 273 SER B OG  1 
ATOM   4168 N N   . LEU B 1 274 ? 27.96200 1.11200   179.67600 1.000 5.22000  ? 274 LEU B N   1 
ATOM   4169 C CA  . LEU B 1 274 ? 28.75100 0.90800   180.88800 1.000 6.42000  ? 274 LEU B CA  1 
ATOM   4170 C C   . LEU B 1 274 ? 28.98200 -0.56700  181.18800 1.000 8.20000  ? 274 LEU B C   1 
ATOM   4171 O O   . LEU B 1 274 ? 29.12400 -0.94800  182.35000 1.000 15.09000 ? 274 LEU B O   1 
ATOM   4172 C CB  . LEU B 1 274 ? 28.08000 1.59500   182.07500 1.000 5.71000  ? 274 LEU B CB  1 
ATOM   4173 C CG  . LEU B 1 274 ? 27.89100 3.10800   181.95700 1.000 6.89000  ? 274 LEU B CG  1 
ATOM   4174 C CD1 . LEU B 1 274 ? 27.00100 3.64700   183.07500 1.000 9.84000  ? 274 LEU B CD1 1 
ATOM   4175 C CD2 . LEU B 1 274 ? 29.25100 3.81400   181.94300 1.000 11.34000 ? 274 LEU B CD2 1 
ATOM   4176 N N   . ASP B 1 275 ? 29.06200 -1.39100  180.16600 1.000 9.24000  ? 275 ASP B N   1 
ATOM   4177 C CA  . ASP B 1 275 ? 29.06300 -2.83300  180.30800 1.000 8.85000  ? 275 ASP B CA  1 
ATOM   4178 C C   . ASP B 1 275 ? 30.45600 -3.38300  180.04100 1.000 7.11000  ? 275 ASP B C   1 
ATOM   4179 O O   . ASP B 1 275 ? 31.03100 -3.08800  178.98300 1.000 7.38000  ? 275 ASP B O   1 
ATOM   4180 C CB  . ASP B 1 275 ? 28.05500 -3.42100  179.31300 1.000 7.42000  ? 275 ASP B CB  1 
ATOM   4181 C CG  . ASP B 1 275 ? 27.83100 -4.90200  179.49000 1.000 10.21000 ? 275 ASP B CG  1 
ATOM   4182 O OD1 . ASP B 1 275 ? 28.63300 -5.56200  180.19100 1.000 8.76000  ? 275 ASP B OD1 1 
ATOM   4183 O OD2 . ASP B 1 275 ? 26.84600 -5.41300  178.90100 1.000 11.17000 ? 275 ASP B OD2 1 
ATOM   4184 N N   . PRO B 1 276 ? 31.03800 -4.17400  180.95200 1.000 7.74000  ? 276 PRO B N   1 
ATOM   4185 C CA  . PRO B 1 276 ? 32.37000 -4.73700  180.66200 1.000 8.87000  ? 276 PRO B CA  1 
ATOM   4186 C C   . PRO B 1 276 ? 32.40700 -5.62600  179.42700 1.000 9.63000  ? 276 PRO B C   1 
ATOM   4187 O O   . PRO B 1 276 ? 33.47800 -5.76100  178.81400 1.000 8.82000  ? 276 PRO B O   1 
ATOM   4188 C CB  . PRO B 1 276 ? 32.71300 -5.51900  181.94000 1.000 10.09000 ? 276 PRO B CB  1 
ATOM   4189 C CG  . PRO B 1 276 ? 31.38900 -5.75300  182.62800 1.000 8.45000  ? 276 PRO B CG  1 
ATOM   4190 C CD  . PRO B 1 276 ? 30.56600 -4.53800  182.30400 1.000 7.54000  ? 276 PRO B CD  1 
ATOM   4191 N N   . ILE B 1 277 ? 31.29100 -6.23900  179.02500 1.000 8.01000  ? 277 ILE B N   1 
ATOM   4192 C CA  . ILE B 1 277 ? 31.28000 -7.04400  177.80700 1.000 6.52000  ? 277 ILE B CA  1 
ATOM   4193 C C   . ILE B 1 277 ? 30.62400 -6.29600  176.64100 1.000 6.72000  ? 277 ILE B C   1 
ATOM   4194 O O   . ILE B 1 277 ? 30.26900 -6.90600  175.63300 1.000 5.98000  ? 277 ILE B O   1 
ATOM   4195 C CB  . ILE B 1 277 ? 30.63900 -8.42600  178.02700 1.000 10.07000 ? 277 ILE B CB  1 
ATOM   4196 C CG1 . ILE B 1 277 ? 29.13000 -8.33800  178.26900 1.000 9.32000  ? 277 ILE B CG1 1 
ATOM   4197 C CG2 . ILE B 1 277 ? 31.33000 -9.16000  179.17400 1.000 8.80000  ? 277 ILE B CG2 1 
ATOM   4198 C CD1 . ILE B 1 277 ? 28.44100 -9.70200  178.15400 1.000 8.82000  ? 277 ILE B CD1 1 
ATOM   4199 N N   . ARG B 1 278 ? 30.49400 -4.97300  176.75300 1.000 5.10000  ? 278 ARG B N   1 
ATOM   4200 C CA  . ARG B 1 278 ? 29.99600 -4.14700  175.65000 1.000 6.61000  ? 278 ARG B CA  1 
ATOM   4201 C C   . ARG B 1 278 ? 30.71300 -4.43400  174.33000 1.000 6.12000  ? 278 ARG B C   1 
ATOM   4202 O O   . ARG B 1 278 ? 30.08100 -4.51700  173.26900 1.000 5.46000  ? 278 ARG B O   1 
ATOM   4203 C CB  . ARG B 1 278 ? 30.15200 -2.68100  176.05000 1.000 7.65000  ? 278 ARG B CB  1 
ATOM   4204 C CG  . ARG B 1 278 ? 29.86700 -1.65300  175.00100 1.000 10.55000 ? 278 ARG B CG  1 
ATOM   4205 C CD  . ARG B 1 278 ? 30.38900 -0.31300  175.50900 1.000 10.59000 ? 278 ARG B CD  1 
ATOM   4206 N NE  . ARG B 1 278 ? 31.81800 -0.17400  175.24900 1.000 10.81000 ? 278 ARG B NE  1 
ATOM   4207 C CZ  . ARG B 1 278 ? 32.53900 0.88300   175.59700 1.000 10.90000 ? 278 ARG B CZ  1 
ATOM   4208 N NH1 . ARG B 1 278 ? 33.83000 0.92700   175.28700 1.000 17.61000 ? 278 ARG B NH1 1 
ATOM   4209 N NH2 . ARG B 1 278 ? 31.97500 1.88600   176.26000 1.000 11.62000 ? 278 ARG B NH2 1 
ATOM   4210 N N   . ASP B 1 279 ? 32.03600 -4.58300  174.36600 1.000 5.71000  ? 279 ASP B N   1 
ATOM   4211 C CA  . ASP B 1 279 ? 32.78400 -4.75200  173.12400 1.000 8.00000  ? 279 ASP B CA  1 
ATOM   4212 C C   . ASP B 1 279 ? 32.48200 -6.08300  172.45400 1.000 8.51000  ? 279 ASP B C   1 
ATOM   4213 O O   . ASP B 1 279 ? 32.65500 -6.21400  171.23600 1.000 7.26000  ? 279 ASP B O   1 
ATOM   4214 C CB  . ASP B 1 279 ? 34.28000 -4.61000  173.40700 1.000 10.02000 ? 279 ASP B CB  1 
ATOM   4215 C CG  . ASP B 1 279 ? 34.67600 -3.17400  173.72300 1.000 11.82000 ? 279 ASP B CG  1 
ATOM   4216 O OD1 . ASP B 1 279 ? 33.79200 -2.28300  173.70800 1.000 10.01000 ? 279 ASP B OD1 1 
ATOM   4217 O OD2 . ASP B 1 279 ? 35.87600 -2.94000  173.98500 1.000 15.08000 ? 279 ASP B OD2 1 
ATOM   4218 N N   . SER B 1 280 ? 32.00100 -7.05900  173.22100 1.000 6.55000  ? 280 SER B N   1 
ATOM   4219 C CA  . SER B 1 280 ? 31.65100 -8.35600  172.65200 1.000 10.21000 ? 280 SER B CA  1 
ATOM   4220 C C   . SER B 1 280 ? 30.43900 -8.23900  171.73400 1.000 9.40000  ? 280 SER B C   1 
ATOM   4221 O O   . SER B 1 280 ? 30.41000 -8.83300  170.64800 1.000 9.07000  ? 280 SER B O   1 
ATOM   4222 C CB  . SER B 1 280 ? 31.40300 -9.34600  173.79500 1.000 10.12000 ? 280 SER B CB  1 
ATOM   4223 O OG  . SER B 1 280 ? 31.23100 -10.67300 173.33200 1.000 10.73000 ? 280 SER B OG  1 
ATOM   4224 N N   . GLY B 1 281 ? 29.44500 -7.45200  172.14500 1.000 6.66000  ? 281 GLY B N   1 
ATOM   4225 C CA  . GLY B 1 281 ? 28.28200 -7.23800  171.29900 1.000 7.47000  ? 281 GLY B CA  1 
ATOM   4226 C C   . GLY B 1 281 ? 28.59000 -6.32200  170.12900 1.000 4.99000  ? 281 GLY B C   1 
ATOM   4227 O O   . GLY B 1 281 ? 28.10600 -6.53900  169.01400 1.000 7.47000  ? 281 GLY B O   1 
ATOM   4228 N N   . ARG B 1 282 ? 29.39300 -5.27700  170.36800 1.000 5.39000  ? 282 ARG B N   1 
ATOM   4229 C CA  . ARG B 1 282 ? 29.85400 -4.43300  169.26900 1.000 6.34000  ? 282 ARG B CA  1 
ATOM   4230 C C   . ARG B 1 282 ? 30.55500 -5.26200  168.20400 1.000 6.32000  ? 282 ARG B C   1 
ATOM   4231 O O   . ARG B 1 282 ? 30.37000 -5.02900  167.00500 1.000 6.19000  ? 282 ARG B O   1 
ATOM   4232 C CB  . ARG B 1 282 ? 30.80700 -3.35300  169.78500 1.000 6.55000  ? 282 ARG B CB  1 
ATOM   4233 C CG  . ARG B 1 282 ? 30.17800 -2.26900  170.63700 1.000 5.17000  ? 282 ARG B CG  1 
ATOM   4234 C CD  . ARG B 1 282 ? 31.26900 -1.31600  171.08900 1.000 6.81000  ? 282 ARG B CD  1 
ATOM   4235 N NE  . ARG B 1 282 ? 30.77300 -0.15800  171.82800 1.000 7.60000  ? 282 ARG B NE  1 
ATOM   4236 C CZ  . ARG B 1 282 ? 31.55600 0.85800   172.18000 1.000 8.93000  ? 282 ARG B CZ  1 
ATOM   4237 N NH1 . ARG B 1 282 ? 31.06400 1.89000   172.84800 1.000 7.70000  ? 282 ARG B NH1 1 
ATOM   4238 N NH2 . ARG B 1 282 ? 32.83800 0.84000   171.83600 1.000 8.71000  ? 282 ARG B NH2 1 
ATOM   4239 N N   . ALA B 1 283 ? 31.37200 -6.23200  168.62400 1.000 6.07000  ? 283 ALA B N   1 
ATOM   4240 C CA  . ALA B 1 283 ? 32.10900 -7.04700  167.66200 1.000 7.38000  ? 283 ALA B CA  1 
ATOM   4241 C C   . ALA B 1 283 ? 31.16400 -7.85300  166.78100 1.000 7.16000  ? 283 ALA B C   1 
ATOM   4242 O O   . ALA B 1 283 ? 31.42500 -8.04100  165.58800 1.000 6.31000  ? 283 ALA B O   1 
ATOM   4243 C CB  . ALA B 1 283 ? 33.07900 -7.97700  168.39400 1.000 7.92000  ? 283 ALA B CB  1 
ATOM   4244 N N   . TYR B 1 284 ? 30.05700 -8.33800  167.34800 1.000 6.29000  ? 284 TYR B N   1 
ATOM   4245 C CA  . TYR B 1 284 ? 29.10900 -9.10800  166.54800 1.000 6.33000  ? 284 TYR B CA  1 
ATOM   4246 C C   . TYR B 1 284 ? 28.43100 -8.23500  165.49800 1.000 5.59000  ? 284 TYR B C   1 
ATOM   4247 O O   . TYR B 1 284 ? 28.28100 -8.64600  164.34000 1.000 5.40000  ? 284 TYR B O   1 
ATOM   4248 C CB  . TYR B 1 284 ? 28.05900 -9.76400  167.44500 1.000 6.48000  ? 284 TYR B CB  1 
ATOM   4249 C CG  . TYR B 1 284 ? 27.15100 -10.69500 166.66800 1.000 6.47000  ? 284 TYR B CG  1 
ATOM   4250 C CD1 . TYR B 1 284 ? 27.68700 -11.64400 165.80900 1.000 6.97000  ? 284 TYR B CD1 1 
ATOM   4251 C CD2 . TYR B 1 284 ? 25.76800 -10.62300 166.79400 1.000 5.50000  ? 284 TYR B CD2 1 
ATOM   4252 C CE1 . TYR B 1 284 ? 26.86600 -12.50200 165.08600 1.000 8.08000  ? 284 TYR B CE1 1 
ATOM   4253 C CE2 . TYR B 1 284 ? 24.93400 -11.47700 166.07700 1.000 5.29000  ? 284 TYR B CE2 1 
ATOM   4254 C CZ  . TYR B 1 284 ? 25.49800 -12.41600 165.22600 1.000 6.05000  ? 284 TYR B CZ  1 
ATOM   4255 O OH  . TYR B 1 284 ? 24.71700 -13.28400 164.49300 1.000 6.49000  ? 284 TYR B OH  1 
ATOM   4256 N N   . ALA B 1 285 ? 27.98700 -7.03800  165.88800 1.000 4.76000  ? 285 ALA B N   1 
ATOM   4257 C CA  . ALA B 1 285 ? 27.39600 -6.13500  164.90300 1.000 6.44000  ? 285 ALA B CA  1 
ATOM   4258 C C   . ALA B 1 285 ? 28.38300 -5.83700  163.78400 1.000 5.63000  ? 285 ALA B C   1 
ATOM   4259 O O   . ALA B 1 285 ? 28.01300 -5.84000  162.60400 1.000 4.26000  ? 285 ALA B O   1 
ATOM   4260 C CB  . ALA B 1 285 ? 26.92200 -4.84000  165.56900 1.000 6.63000  ? 285 ALA B CB  1 
ATOM   4261 N N   . LYS B 1 286 ? 29.65800 -5.63100  164.12700 1.000 4.27000  ? 286 LYS B N   1 
ATOM   4262 C CA  . LYS B 1 286 ? 30.65500 -5.39800  163.08200 1.000 5.55000  ? 286 LYS B CA  1 
ATOM   4263 C C   . LYS B 1 286 ? 30.83900 -6.62600  162.19200 1.000 7.48000  ? 286 LYS B C   1 
ATOM   4264 O O   . LYS B 1 286 ? 31.04900 -6.48700  160.98100 1.000 6.28000  ? 286 LYS B O   1 
ATOM   4265 C CB  . LYS B 1 286 ? 31.98700 -4.97600  163.70000 1.000 6.13000  ? 286 LYS B CB  1 
ATOM   4266 C CG  . LYS B 1 286 ? 31.95000 -3.58600  164.33000 1.000 5.88000  ? 286 LYS B CG  1 
ATOM   4267 C CD  . LYS B 1 286 ? 33.16400 -3.34600  165.22900 1.000 14.59000 ? 286 LYS B CD  1 
ATOM   4268 C CE  . LYS B 1 286 ? 34.46700 -3.33400  164.45200 1.000 17.94000 ? 286 LYS B CE  1 
ATOM   4269 N NZ  . LYS B 1 286 ? 35.63400 -3.23800  165.39200 1.000 9.96000  ? 286 LYS B NZ  1 
ATOM   4270 N N   . ALA B 1 287 ? 30.76900 -7.83200  162.76900 1.000 5.90000  ? 287 ALA B N   1 
ATOM   4271 C CA  . ALA B 1 287 ? 30.90000 -9.04800  161.96900 1.000 7.35000  ? 287 ALA B CA  1 
ATOM   4272 C C   . ALA B 1 287 ? 29.74100 -9.19500  160.99100 1.000 7.49000  ? 287 ALA B C   1 
ATOM   4273 O O   . ALA B 1 287 ? 29.92100 -9.69100  159.87000 1.000 6.89000  ? 287 ALA B O   1 
ATOM   4274 C CB  . ALA B 1 287 ? 30.97400 -10.27700 162.88000 1.000 6.53000  ? 287 ALA B CB  1 
ATOM   4275 N N   . LEU B 1 288 ? 28.53600 -8.79400  161.40100 1.000 6.24000  ? 288 LEU B N   1 
ATOM   4276 C CA  . LEU B 1 288 ? 27.40100 -8.88400  160.48500 1.000 6.18000  ? 288 LEU B CA  1 
ATOM   4277 C C   . LEU B 1 288 ? 27.55800 -7.91300  159.32500 1.000 5.51000  ? 288 LEU B C   1 
ATOM   4278 O O   . LEU B 1 288 ? 27.25700 -8.25300  158.17400 1.000 5.67000  ? 288 LEU B O   1 
ATOM   4279 C CB  . LEU B 1 288 ? 26.09900 -8.61800  161.23800 1.000 5.98000  ? 288 LEU B CB  1 
ATOM   4280 C CG  . LEU B 1 288 ? 25.73300 -9.70900  162.24200 1.000 6.69000  ? 288 LEU B CG  1 
ATOM   4281 C CD1 . LEU B 1 288 ? 24.50400 -9.29200  163.05700 1.000 10.48000 ? 288 LEU B CD1 1 
ATOM   4282 C CD2 . LEU B 1 288 ? 25.50400 -11.03200 161.53900 1.000 9.11000  ? 288 LEU B CD2 1 
ATOM   4283 N N   . ILE B 1 289 ? 28.03400 -6.70300  159.60900 1.000 5.30000  ? 289 ILE B N   1 
ATOM   4284 C CA  . ILE B 1 289 ? 28.28500 -5.73400  158.54500 1.000 5.58000  ? 289 ILE B CA  1 
ATOM   4285 C C   . ILE B 1 289 ? 29.33900 -6.26400  157.58400 1.000 6.18000  ? 289 ILE B C   1 
ATOM   4286 O O   . ILE B 1 289 ? 29.20400 -6.14100  156.35900 1.000 6.88000  ? 289 ILE B O   1 
ATOM   4287 C CB  . ILE B 1 289 ? 28.70400 -4.38900  159.15800 1.000 5.45000  ? 289 ILE B CB  1 
ATOM   4288 C CG1 . ILE B 1 289 ? 27.51200 -3.76400  159.88400 1.000 6.42000  ? 289 ILE B CG1 1 
ATOM   4289 C CG2 . ILE B 1 289 ? 29.26600 -3.45500  158.07900 1.000 6.81000  ? 289 ILE B CG2 1 
ATOM   4290 C CD1 . ILE B 1 289 ? 27.93400 -2.76600  160.90500 1.000 8.44000  ? 289 ILE B CD1 1 
ATOM   4291 N N   . ASP B 1 290 ? 30.40300 -6.87200  158.12900 1.000 7.63000  ? 290 ASP B N   1 
ATOM   4292 C CA  . ASP B 1 290 ? 31.45400 -7.46800  157.30600 1.000 7.97000  ? 290 ASP B CA  1 
ATOM   4293 C C   . ASP B 1 290 ? 30.91100 -8.56900  156.40900 1.000 10.99000 ? 290 ASP B C   1 
ATOM   4294 O O   . ASP B 1 290 ? 31.48400 -8.84600  155.34500 1.000 9.46000  ? 290 ASP B O   1 
ATOM   4295 C CB  . ASP B 1 290 ? 32.56200 -8.05300  158.19500 1.000 7.42000  ? 290 ASP B CB  1 
ATOM   4296 C CG  . ASP B 1 290 ? 33.55300 -7.00700  158.69600 1.000 14.90000 ? 290 ASP B CG  1 
ATOM   4297 O OD1 . ASP B 1 290 ? 33.59900 -5.88800  158.14300 1.000 12.91000 ? 290 ASP B OD1 1 
ATOM   4298 O OD2 . ASP B 1 290 ? 34.30400 -7.33100  159.64600 1.000 17.23000 ? 290 ASP B OD2 1 
ATOM   4299 N N   . ALA B 1 291 ? 29.82600 -9.22000  156.82200 1.000 5.50000  ? 291 ALA B N   1 
ATOM   4300 C CA  . ALA B 1 291 ? 29.18500 -10.25700 156.02600 1.000 8.24000  ? 291 ALA B CA  1 
ATOM   4301 C C   . ALA B 1 291 ? 28.05200 -9.72200  155.15100 1.000 7.64000  ? 291 ALA B C   1 
ATOM   4302 O O   . ALA B 1 291 ? 27.37800 -10.51100 154.47400 1.000 8.80000  ? 291 ALA B O   1 
ATOM   4303 C CB  . ALA B 1 291 ? 28.66000 -11.36600 156.94400 1.000 9.58000  ? 291 ALA B CB  1 
ATOM   4304 N N   . GLY B 1 292 ? 27.82200 -8.41200  155.15300 1.000 7.94000  ? 292 GLY B N   1 
ATOM   4305 C CA  . GLY B 1 292 ? 26.76500 -7.82800  154.34400 1.000 9.24000  ? 292 GLY B CA  1 
ATOM   4306 C C   . GLY B 1 292 ? 25.35700 -8.08400  154.84500 1.000 9.44000  ? 292 GLY B C   1 
ATOM   4307 O O   . GLY B 1 292 ? 24.42200 -8.11700  154.04100 1.000 8.87000  ? 292 GLY B O   1 
ATOM   4308 N N   . ARG B 1 293 ? 25.17200 -8.26100  156.15200 1.000 6.23000  ? 293 ARG B N   1 
ATOM   4309 C CA  . ARG B 1 293 ? 23.87500 -8.63400  156.71400 1.000 7.67000  ? 293 ARG B CA  1 
ATOM   4310 C C   . ARG B 1 293 ? 23.28900 -7.47300  157.50200 1.000 8.37000  ? 293 ARG B C   1 
ATOM   4311 O O   . ARG B 1 293 ? 23.98000 -6.89400  158.34500 1.000 9.42000  ? 293 ARG B O   1 
ATOM   4312 C CB  . ARG B 1 293 ? 24.00800 -9.85700  157.63000 1.000 7.77000  ? 293 ARG B CB  1 
ATOM   4313 C CG  . ARG B 1 293 ? 24.67700 -11.05500 156.95800 1.000 9.57000  ? 293 ARG B CG  1 
ATOM   4314 C CD  . ARG B 1 293 ? 23.89000 -11.50600 155.75200 1.000 9.39000  ? 293 ARG B CD  1 
ATOM   4315 N NE  . ARG B 1 293 ? 22.64700 -12.18400 156.12500 1.000 8.99000  ? 293 ARG B NE  1 
ATOM   4316 C CZ  . ARG B 1 293 ? 21.84300 -12.78500 155.25800 1.000 10.16000 ? 293 ARG B CZ  1 
ATOM   4317 N NH1 . ARG B 1 293 ? 22.14500 -12.79100 153.96000 1.000 16.11000 ? 293 ARG B NH1 1 
ATOM   4318 N NH2 . ARG B 1 293 ? 20.74200 -13.39000 155.68000 1.000 13.28000 ? 293 ARG B NH2 1 
ATOM   4319 N N   . ASP B 1 294 ? 22.00700 -7.16300  157.25800 1.000 7.44000  ? 294 ASP B N   1 
ATOM   4320 C CA  . ASP B 1 294 ? 21.34000 -6.06900  157.97200 1.000 6.67000  ? 294 ASP B CA  1 
ATOM   4321 C C   . ASP B 1 294 ? 21.49200 -6.23100  159.47000 1.000 9.08000  ? 294 ASP B C   1 
ATOM   4322 O O   . ASP B 1 294 ? 21.40200 -7.33900  160.00000 1.000 9.59000  ? 294 ASP B O   1 
ATOM   4323 C CB  . ASP B 1 294 ? 19.84500 -6.03100  157.66900 1.000 6.86000  ? 294 ASP B CB  1 
ATOM   4324 C CG  . ASP B 1 294 ? 19.54300 -5.87100  156.21200 1.000 10.11000 ? 294 ASP B CG  1 
ATOM   4325 O OD1 . ASP B 1 294 ? 20.36000 -5.25800  155.50200 1.000 9.21000  ? 294 ASP B OD1 1 
ATOM   4326 O OD2 . ASP B 1 294 ? 18.46500 -6.34400  155.79200 1.000 12.68000 ? 294 ASP B OD2 1 
ATOM   4327 N N   . CYS B 1 295 ? 21.66600 -5.10900  160.15700 1.000 6.09000  ? 295 CYS B N   1 
ATOM   4328 C CA  . CYS B 1 295 ? 21.78700 -5.15400  161.60800 1.000 6.49000  ? 295 CYS B CA  1 
ATOM   4329 C C   . CYS B 1 295 ? 21.37400 -3.80500  162.17300 1.000 8.90000  ? 295 CYS B C   1 
ATOM   4330 O O   . CYS B 1 295 ? 21.88300 -2.76900  161.73700 1.000 9.70000  ? 295 CYS B O   1 
ATOM   4331 C CB  . CYS B 1 295 ? 23.22800 -5.49500  162.00800 1.000 6.61000  ? 295 CYS B CB  1 
ATOM   4332 S SG  . CYS B 1 295 ? 23.50100 -5.64100  163.79700 1.000 13.51000 ? 295 CYS B SG  1 
ATOM   4333 N N   . VAL B 1 296 ? 20.45500 -3.81700  163.13200 1.000 5.91000  ? 296 VAL B N   1 
ATOM   4334 C CA  . VAL B 1 296 ? 20.16600 -2.63300  163.92900 1.000 6.08000  ? 296 VAL B CA  1 
ATOM   4335 C C   . VAL B 1 296 ? 21.07600 -2.69500  165.14600 1.000 7.46000  ? 296 VAL B C   1 
ATOM   4336 O O   . VAL B 1 296 ? 20.99100 -3.64400  165.92700 1.000 9.16000  ? 296 VAL B O   1 
ATOM   4337 C CB  . VAL B 1 296 ? 18.69300 -2.58300  164.35500 1.000 8.24000  ? 296 VAL B CB  1 
ATOM   4338 C CG1 . VAL B 1 296 ? 18.45100 -1.38900  165.29100 1.000 7.34000  ? 296 VAL B CG1 1 
ATOM   4339 C CG2 . VAL B 1 296 ? 17.78000 -2.51300  163.14400 1.000 8.05000  ? 296 VAL B CG2 1 
ATOM   4340 N N   . PHE B 1 297 ? 21.94700 -1.70500  165.30500 1.000 5.77000  ? 297 PHE B N   1 
ATOM   4341 C CA  . PHE B 1 297 ? 22.81800 -1.62400  166.47600 1.000 5.00000  ? 297 PHE B CA  1 
ATOM   4342 C C   . PHE B 1 297 ? 22.31200 -0.52400  167.39400 1.000 5.50000  ? 297 PHE B C   1 
ATOM   4343 O O   . PHE B 1 297 ? 22.28000 0.64600   167.00200 1.000 6.44000  ? 297 PHE B O   1 
ATOM   4344 C CB  . PHE B 1 297 ? 24.26300 -1.34500  166.07700 1.000 5.47000  ? 297 PHE B CB  1 
ATOM   4345 C CG  . PHE B 1 297 ? 25.16900 -1.08500  167.24600 1.000 7.97000  ? 297 PHE B CG  1 
ATOM   4346 C CD1 . PHE B 1 297 ? 25.55600 -2.12900  168.07300 1.000 7.79000  ? 297 PHE B CD1 1 
ATOM   4347 C CD2 . PHE B 1 297 ? 25.64100 0.19000   167.50900 1.000 6.87000  ? 297 PHE B CD2 1 
ATOM   4348 C CE1 . PHE B 1 297 ? 26.39800 -1.91000  169.15000 1.000 7.51000  ? 297 PHE B CE1 1 
ATOM   4349 C CE2 . PHE B 1 297 ? 26.48600 0.42600   168.59400 1.000 8.11000  ? 297 PHE B CE2 1 
ATOM   4350 C CZ  . PHE B 1 297 ? 26.85800 -0.62700  169.41700 1.000 7.68000  ? 297 PHE B CZ  1 
ATOM   4351 N N   . LEU B 1 298 ? 21.92400 -0.89900  168.61000 1.000 6.40000  ? 298 LEU B N   1 
ATOM   4352 C CA  . LEU B 1 298 ? 21.49100 0.04400   169.63500 1.000 6.56000  ? 298 LEU B CA  1 
ATOM   4353 C C   . LEU B 1 298 ? 22.41000 -0.12500  170.82900 1.000 6.27000  ? 298 LEU B C   1 
ATOM   4354 O O   . LEU B 1 298 ? 22.45600 -1.20800  171.42000 1.000 8.90000  ? 298 LEU B O   1 
ATOM   4355 C CB  . LEU B 1 298 ? 20.04700 -0.22500  170.06100 1.000 5.75000  ? 298 LEU B CB  1 
ATOM   4356 C CG  . LEU B 1 298 ? 18.96300 -0.17800  168.98200 1.000 7.04000  ? 298 LEU B CG  1 
ATOM   4357 C CD1 . LEU B 1 298 ? 17.59100 -0.44000  169.61500 1.000 10.74000 ? 298 LEU B CD1 1 
ATOM   4358 C CD2 . LEU B 1 298 ? 18.98300 1.15100   168.26500 1.000 12.64000 ? 298 LEU B CD2 1 
ATOM   4359 N N   . GLU B 1 299 ? 23.12600 0.93600   171.18900 1.000 4.69000  ? 299 GLU B N   1 
ATOM   4360 C CA  . GLU B 1 299 ? 23.89000 0.96500   172.43500 1.000 6.35000  ? 299 GLU B CA  1 
ATOM   4361 C C   . GLU B 1 299 ? 23.20700 1.96000   173.36600 1.000 5.19000  ? 299 GLU B C   1 
ATOM   4362 O O   . GLU B 1 299 ? 23.16900 3.16300   173.08700 1.000 5.82000  ? 299 GLU B O   1 
ATOM   4363 C CB  . GLU B 1 299 ? 25.35600 1.33300   172.20200 1.000 7.60000  ? 299 GLU B CB  1 
ATOM   4364 C CG  . GLU B 1 299 ? 26.14200 1.36000   173.51400 1.000 5.69000  ? 299 GLU B CG  1 
ATOM   4365 C CD  . GLU B 1 299 ? 27.62700 1.11100   173.33800 1.000 9.16000  ? 299 GLU B CD  1 
ATOM   4366 O OE1 . GLU B 1 299 ? 28.00600 0.07600   172.73700 1.000 9.07000  ? 299 GLU B OE1 1 
ATOM   4367 O OE2 . GLU B 1 299 ? 28.42300 1.95700   173.81900 1.000 8.94000  ? 299 GLU B OE2 1 
ATOM   4368 N N   . MET B 1 300 ? 22.65500 1.45700   174.46400 1.000 5.09000  ? 300 MET B N   1 
ATOM   4369 C CA  . MET B 1 300 ? 21.96200 2.30200   175.42700 1.000 7.07000  ? 300 MET B CA  1 
ATOM   4370 C C   . MET B 1 300 ? 22.99300 3.07100   176.24700 1.000 6.49000  ? 300 MET B C   1 
ATOM   4371 O O   . MET B 1 300 ? 23.87600 2.47100   176.87000 1.000 7.99000  ? 300 MET B O   1 
ATOM   4372 C CB  . MET B 1 300 ? 21.05300 1.44600   176.31100 1.000 6.54000  ? 300 MET B CB  1 
ATOM   4373 C CG  . MET B 1 300 ? 20.06900 0.59500   175.49100 1.000 9.25000  ? 300 MET B CG  1 
ATOM   4374 S SD  . MET B 1 300 ? 19.10600 1.62500   174.33600 1.000 10.69000 ? 300 MET B SD  1 
ATOM   4375 C CE  . MET B 1 300 ? 18.04200 0.39600   173.55300 1.000 7.30000  ? 300 MET B CE  1 
ATOM   4376 N N   . ARG B 1 301 ? 22.89100 4.40100   176.23400 1.000 6.54000  ? 301 ARG B N   1 
ATOM   4377 C CA  . ARG B 1 301 ? 23.94800 5.25200   176.76300 1.000 4.58000  ? 301 ARG B CA  1 
ATOM   4378 C C   . ARG B 1 301 ? 23.65200 5.61700   178.20800 1.000 6.87000  ? 301 ARG B C   1 
ATOM   4379 O O   . ARG B 1 301 ? 22.55200 6.07500   178.52500 1.000 7.09000  ? 301 ARG B O   1 
ATOM   4380 C CB  . ARG B 1 301 ? 24.10900 6.51400   175.91100 1.000 6.63000  ? 301 ARG B CB  1 
ATOM   4381 C CG  . ARG B 1 301 ? 24.44700 6.17100   174.44800 1.000 6.91000  ? 301 ARG B CG  1 
ATOM   4382 C CD  . ARG B 1 301 ? 25.06900 7.34200   173.70300 1.000 9.04000  ? 301 ARG B CD  1 
ATOM   4383 N NE  . ARG B 1 301 ? 24.13500 8.43500   173.43200 1.000 9.71000  ? 301 ARG B NE  1 
ATOM   4384 C CZ  . ARG B 1 301 ? 23.49000 8.62900   172.27800 1.000 12.27000 ? 301 ARG B CZ  1 
ATOM   4385 N NH1 . ARG B 1 301 ? 23.62600 7.78200   171.25800 1.000 9.50000  ? 301 ARG B NH1 1 
ATOM   4386 N NH2 . ARG B 1 301 ? 22.69700 9.68700   172.13700 1.000 12.22000 ? 301 ARG B NH2 1 
ATOM   4387 N N   . GLY B 1 302 ? 24.63200 5.39100   179.08100 1.000 5.71000  ? 302 GLY B N   1 
ATOM   4388 C CA  . GLY B 1 302 ? 24.49700 5.76200   180.47700 1.000 6.24000  ? 302 GLY B CA  1 
ATOM   4389 C C   . GLY B 1 302 ? 23.90300 4.69800   181.37500 1.000 5.51000  ? 302 GLY B C   1 
ATOM   4390 O O   . GLY B 1 302 ? 23.53100 5.01200   182.51300 1.000 6.35000  ? 302 GLY B O   1 
ATOM   4391 N N   . VAL B 1 303 ? 23.78200 3.45400   180.89900 1.000 7.12000  ? 303 VAL B N   1 
ATOM   4392 C CA  . VAL B 1 303 ? 23.23600 2.36300   181.70000 1.000 7.53000  ? 303 VAL B CA  1 
ATOM   4393 C C   . VAL B 1 303 ? 24.18000 1.17100   181.62400 1.000 6.01000  ? 303 VAL B C   1 
ATOM   4394 O O   . VAL B 1 303 ? 25.04200 1.07900   180.74700 1.000 6.25000  ? 303 VAL B O   1 
ATOM   4395 C CB  . VAL B 1 303 ? 21.80800 1.94000   181.26600 1.000 7.99000  ? 303 VAL B CB  1 
ATOM   4396 C CG1 . VAL B 1 303 ? 20.80700 3.06000   181.52900 1.000 7.82000  ? 303 VAL B CG1 1 
ATOM   4397 C CG2 . VAL B 1 303 ? 21.77900 1.50300   179.79300 1.000 8.40000  ? 303 VAL B CG2 1 
ATOM   4398 N N   . THR B 1 304 ? 23.97500 0.23600   182.55000 1.000 6.69000  ? 304 THR B N   1 
ATOM   4399 C CA  . THR B 1 304 ? 24.83500 -0.91900  182.74700 1.000 5.53000  ? 304 THR B CA  1 
ATOM   4400 C C   . THR B 1 304 ? 24.27000 -2.16400  182.07500 1.000 7.60000  ? 304 THR B C   1 
ATOM   4401 O O   . THR B 1 304 ? 23.13600 -2.19100  181.59000 1.000 6.14000  ? 304 THR B O   1 
ATOM   4402 C CB  . THR B 1 304 ? 24.97500 -1.20900  184.24200 1.000 7.41000  ? 304 THR B CB  1 
ATOM   4403 O OG1 . THR B 1 304 ? 23.66400 -1.46900  184.76800 1.000 8.68000  ? 304 THR B OG1 1 
ATOM   4404 C CG2 . THR B 1 304 ? 25.59000 -0.02500  184.98300 1.000 7.26000  ? 304 THR B CG2 1 
ATOM   4405 N N   . HIS B 1 305 ? 25.08300 -3.22300  182.09800 1.000 6.25000  ? 305 HIS B N   1 
ATOM   4406 C CA  . HIS B 1 305 ? 24.58200 -4.57600  181.92500 1.000 7.11000  ? 305 HIS B CA  1 
ATOM   4407 C C   . HIS B 1 305 ? 23.33000 -4.77800  182.77600 1.000 7.78000  ? 305 HIS B C   1 
ATOM   4408 O O   . HIS B 1 305 ? 23.17300 -4.16400  183.83400 1.000 8.67000  ? 305 HIS B O   1 
ATOM   4409 C CB  . HIS B 1 305 ? 25.68000 -5.56400  182.33000 1.000 7.14000  ? 305 HIS B CB  1 
ATOM   4410 C CG  . HIS B 1 305 ? 25.51400 -6.94200  181.77100 1.000 8.29000  ? 305 HIS B CG  1 
ATOM   4411 N ND1 . HIS B 1 305 ? 25.93100 -7.28700  180.50400 1.000 8.50000  ? 305 HIS B ND1 1 
ATOM   4412 C CD2 . HIS B 1 305 ? 25.02400 -8.07500  182.32800 1.000 8.87000  ? 305 HIS B CD2 1 
ATOM   4413 C CE1 . HIS B 1 305 ? 25.68800 -8.57000  180.29500 1.000 10.30000 ? 305 HIS B CE1 1 
ATOM   4414 N NE2 . HIS B 1 305 ? 25.13500 -9.07100  181.38500 1.000 9.48000  ? 305 HIS B NE2 1 
ATOM   4415 N N   . SER B 1 306 ? 22.43600 -5.64700  182.30200 1.000 8.64000  ? 306 SER B N   1 
ATOM   4416 C CA  . SER B 1 306 ? 21.21200 -6.06900  182.98500 1.000 8.52000  ? 306 SER B CA  1 
ATOM   4417 C C   . SER B 1 306 ? 20.11900 -5.00600  182.96800 1.000 8.15000  ? 306 SER B C   1 
ATOM   4418 O O   . SER B 1 306 ? 19.12800 -5.16300  183.68800 1.000 8.42000  ? 306 SER B O   1 
ATOM   4419 C CB  . SER B 1 306 ? 21.44900 -6.48900  184.44800 1.000 9.21000  ? 306 SER B CB  1 
ATOM   4420 O OG  . SER B 1 306 ? 22.30600 -7.62400  184.55900 1.000 11.91000 ? 306 SER B OG  1 
ATOM   4421 N N   . PHE B 1 307 ? 20.24800 -3.94400  182.15400 1.000 6.54000  ? 307 PHE B N   1 
ATOM   4422 C CA  . PHE B 1 307 ? 19.31500 -2.82300  182.27700 1.000 7.77000  ? 307 PHE B CA  1 
ATOM   4423 C C   . PHE B 1 307 ? 17.88300 -3.23100  181.96600 1.000 8.62000  ? 307 PHE B C   1 
ATOM   4424 O O   . PHE B 1 307 ? 16.94900 -2.58600  182.45700 1.000 8.88000  ? 307 PHE B O   1 
ATOM   4425 C CB  . PHE B 1 307 ? 19.73300 -1.64500  181.38000 1.000 7.55000  ? 307 PHE B CB  1 
ATOM   4426 C CG  . PHE B 1 307 ? 19.53200 -1.87900  179.90600 1.000 8.30000  ? 307 PHE B CG  1 
ATOM   4427 C CD1 . PHE B 1 307 ? 18.27200 -1.74200  179.31400 1.000 6.79000  ? 307 PHE B CD1 1 
ATOM   4428 C CD2 . PHE B 1 307 ? 20.61100 -2.21500  179.10300 1.000 9.40000  ? 307 PHE B CD2 1 
ATOM   4429 C CE1 . PHE B 1 307 ? 18.09500 -1.96200  177.95700 1.000 10.80000 ? 307 PHE B CE1 1 
ATOM   4430 C CE2 . PHE B 1 307 ? 20.44500 -2.42500  177.73800 1.000 8.99000  ? 307 PHE B CE2 1 
ATOM   4431 C CZ  . PHE B 1 307 ? 19.18700 -2.30300  177.16600 1.000 9.64000  ? 307 PHE B CZ  1 
ATOM   4432 N N   . THR B 1 308 ? 17.69000 -4.29600  181.18500 1.000 6.54000  ? 308 THR B N   1 
ATOM   4433 C CA  . THR B 1 308 ? 16.33700 -4.74700  180.87100 1.000 7.37000  ? 308 THR B CA  1 
ATOM   4434 C C   . THR B 1 308 ? 15.56800 -5.20000  182.10000 1.000 8.78000  ? 308 THR B C   1 
ATOM   4435 O O   . THR B 1 308 ? 14.33900 -5.28000  182.04500 1.000 8.66000  ? 308 THR B O   1 
ATOM   4436 C CB  . THR B 1 308 ? 16.36300 -5.90000  179.85800 1.000 9.63000  ? 308 THR B CB  1 
ATOM   4437 O OG1 . THR B 1 308 ? 17.31300 -6.89200  180.28000 1.000 10.62000 ? 308 THR B OG1 1 
ATOM   4438 C CG2 . THR B 1 308 ? 16.73900 -5.38500  178.48500 1.000 8.03000  ? 308 THR B CG2 1 
ATOM   4439 N N   . ASN B 1 309 ? 16.24700 -5.52200  183.20100 1.000 6.96000  ? 309 ASN B N   1 
ATOM   4440 C CA  . ASN B 1 309 ? 15.56400 -5.99800  184.39600 1.000 7.96000  ? 309 ASN B CA  1 
ATOM   4441 C C   . ASN B 1 309 ? 15.67200 -5.01200  185.55400 1.000 9.35000  ? 309 ASN B C   1 
ATOM   4442 O O   . ASN B 1 309 ? 15.49700 -5.39900  186.71400 1.000 8.63000  ? 309 ASN B O   1 
ATOM   4443 C CB  . ASN B 1 309 ? 16.11000 -7.37500  184.79200 1.000 9.94000  ? 309 ASN B CB  1 
ATOM   4444 C CG  . ASN B 1 309 ? 15.94600 -8.40800  183.67500 1.000 10.38000 ? 309 ASN B CG  1 
ATOM   4445 O OD1 . ASN B 1 309 ? 16.74300 -8.45400  182.73700 1.000 13.04000 ? 309 ASN B OD1 1 
ATOM   4446 N ND2 . ASN B 1 309 ? 14.90200 -9.22500  183.76600 1.000 10.55000 ? 309 ASN B ND2 1 
ATOM   4447 N N   . LEU B 1 310 ? 15.94600 -3.73600  185.25800 1.000 7.38000  ? 310 LEU B N   1 
ATOM   4448 C CA  . LEU B 1 310 ? 16.06000 -2.68700  186.26400 1.000 6.95000  ? 310 LEU B CA  1 
ATOM   4449 C C   . LEU B 1 310 ? 14.96800 -1.63000  186.11700 1.000 7.90000  ? 310 LEU B C   1 
ATOM   4450 O O   . LEU B 1 310 ? 15.15100 -0.48900  186.55000 1.000 7.81000  ? 310 LEU B O   1 
ATOM   4451 C CB  . LEU B 1 310 ? 17.43800 -2.02500  186.18300 1.000 6.14000  ? 310 LEU B CB  1 
ATOM   4452 C CG  . LEU B 1 310 ? 18.66000 -2.94700  186.16600 1.000 7.60000  ? 310 LEU B CG  1 
ATOM   4453 C CD1 . LEU B 1 310 ? 19.95200 -2.14300  186.09700 1.000 10.48000 ? 310 LEU B CD1 1 
ATOM   4454 C CD2 . LEU B 1 310 ? 18.66600 -3.84900  187.40400 1.000 7.78000  ? 310 LEU B CD2 1 
ATOM   4455 N N   . ARG B 1 311 ? 13.85900 -1.97600  185.47000 1.000 6.35000  ? 311 ARG B N   1 
ATOM   4456 C CA  . ARG B 1 311 ? 12.88000 -0.94200  185.02600 1.000 8.62000  ? 311 ARG B CA  1 
ATOM   4457 C C   . ARG B 1 311 ? 12.08200 -0.24100  186.13500 1.000 9.50000  ? 311 ARG B C   1 
ATOM   4458 O O   . ARG B 1 311 ? 11.41900 0.73600   185.81300 1.000 10.09000 ? 311 ARG B O   1 
ATOM   4459 C CB  . ARG B 1 311 ? 11.92600 -1.56500  184.00100 1.000 9.18000  ? 311 ARG B CB  1 
ATOM   4460 C CG  . ARG B 1 311 ? 12.52300 -1.80000  182.62700 1.000 8.90000  ? 311 ARG B CG  1 
ATOM   4461 C CD  . ARG B 1 311 ? 12.43000 -3.25500  182.32800 1.000 17.62000 ? 311 ARG B CD  1 
ATOM   4462 N NE  . ARG B 1 311 ? 11.21900 -3.89200  181.81100 1.000 28.15000 ? 311 ARG B NE  1 
ATOM   4463 C CZ  . ARG B 1 311 ? 10.15900 -4.31900  182.47900 1.000 10.25000 ? 311 ARG B CZ  1 
ATOM   4464 N NH1 . ARG B 1 311 ? 9.04100  -3.63300  182.40500 1.000 14.78000 ? 311 ARG B NH1 1 
ATOM   4465 N NH2 . ARG B 1 311 ? 10.19900 -5.44800  183.16200 1.000 11.50000 ? 311 ARG B NH2 1 
ATOM   4466 N N   . GLN B 1 312 ? 12.10400 -0.77800  187.34100 1.000 7.71000  ? 312 GLN B N   1 
ATOM   4467 C CA  . GLN B 1 312 ? 11.42900 -0.07800  188.42900 1.000 10.08000 ? 312 GLN B CA  1 
ATOM   4468 C C   . GLN B 1 312 ? 12.36700 0.89000   189.14200 1.000 10.41000 ? 312 GLN B C   1 
ATOM   4469 O O   . GLN B 1 312 ? 12.02600 2.06100   189.35100 1.000 11.30000 ? 312 GLN B O   1 
ATOM   4470 C CB  . GLN B 1 312 ? 10.84700 -1.08700  189.43200 1.000 8.83000  ? 312 GLN B CB  1 
ATOM   4471 C CG  . GLN B 1 312 ? 10.10300 -0.44300  190.59600 1.000 12.84000 ? 312 GLN B CG  1 
ATOM   4472 C CD  . GLN B 1 312 ? 8.76400  0.15300   190.18300 1.000 19.06000 ? 312 GLN B CD  1 
ATOM   4473 O OE1 . GLN B 1 312 ? 8.16100  -0.25900  189.18500 1.000 13.56000 ? 312 GLN B OE1 1 
ATOM   4474 N NE2 . GLN B 1 312 ? 8.28900  1.12500   190.95400 1.000 17.59000 ? 312 GLN B NE2 1 
ATOM   4475 N N   . MET B 1 313 ? 13.56200 0.42300   189.51400 1.000 9.55000  ? 313 MET B N   1 
ATOM   4476 C CA  . MET B 1 313 ? 14.48000 1.25800   190.27900 1.000 9.38000  ? 313 MET B CA  1 
ATOM   4477 C C   . MET B 1 313 ? 15.31500 2.18200   189.40300 1.000 13.12000 ? 313 MET B C   1 
ATOM   4478 O O   . MET B 1 313 ? 15.84200 3.18100   189.91000 1.000 13.07000 ? 313 MET B O   1 
ATOM   4479 C CB  . MET B 1 313 ? 15.40000 0.38100   191.13500 1.000 10.30000 ? 313 MET B CB  1 
ATOM   4480 C CG  . MET B 1 313 ? 14.65600 -0.41200  192.19600 1.000 14.24000 ? 313 MET B CG  1 
ATOM   4481 S SD  . MET B 1 313 ? 13.70000 0.63900   193.31300 1.000 20.95000 ? 313 MET B SD  1 
ATOM   4482 C CE  . MET B 1 313 ? 15.02000 1.37200   194.28700 1.000 21.11000 ? 313 MET B CE  1 
ATOM   4483 N N   . VAL B 1 314 ? 15.46000 1.87200   188.11500 1.000 11.90000 ? 314 VAL B N   1 
ATOM   4484 C CA  . VAL B 1 314 ? 16.09700 2.76800   187.15000 1.000 8.56000  ? 314 VAL B CA  1 
ATOM   4485 C C   . VAL B 1 314 ? 15.04900 3.03600   186.07600 1.000 8.80000  ? 314 VAL B C   1 
ATOM   4486 O O   . VAL B 1 314 ? 15.06000 2.38300   185.02600 1.000 8.21000  ? 314 VAL B O   1 
ATOM   4487 C CB  . VAL B 1 314 ? 17.38200 2.16300   186.55800 1.000 10.32000 ? 314 VAL B CB  1 
ATOM   4488 C CG1 . VAL B 1 314 ? 18.08800 3.18300   185.66300 1.000 9.81000  ? 314 VAL B CG1 1 
ATOM   4489 C CG2 . VAL B 1 314 ? 18.32500 1.70500   187.66900 1.000 10.82000 ? 314 VAL B CG2 1 
ATOM   4490 N N   . PRO B 1 315 ? 14.10100 3.94600   186.31600 1.000 11.11000 ? 315 PRO B N   1 
ATOM   4491 C CA  . PRO B 1 315 ? 12.91200 4.02200   185.44900 1.000 13.21000 ? 315 PRO B CA  1 
ATOM   4492 C C   . PRO B 1 315 ? 13.21200 4.34800   183.99700 1.000 10.44000 ? 315 PRO B C   1 
ATOM   4493 O O   . PRO B 1 315 ? 12.40700 3.99200   183.12600 1.000 11.44000 ? 315 PRO B O   1 
ATOM   4494 C CB  . PRO B 1 315 ? 12.07000 5.12900   186.10400 1.000 14.54000 ? 315 PRO B CB  1 
ATOM   4495 C CG  . PRO B 1 315 ? 12.53500 5.16900   187.52200 1.000 13.73000 ? 315 PRO B CG  1 
ATOM   4496 C CD  . PRO B 1 315 ? 14.00700 4.84800   187.47400 1.000 13.31000 ? 315 PRO B CD  1 
ATOM   4497 N N   . SER B 1 316 ? 14.35000 4.98100   183.69900 1.000 10.30000 ? 316 SER B N   1 
ATOM   4498 C CA  . SER B 1 316 ? 14.67100 5.29200   182.30900 1.000 11.77000 ? 316 SER B CA  1 
ATOM   4499 C C   . SER B 1 316 ? 14.91200 4.04200   181.46600 1.000 10.13000 ? 316 SER B C   1 
ATOM   4500 O O   . SER B 1 316 ? 14.85000 4.12400   180.23400 1.000 9.48000  ? 316 SER B O   1 
ATOM   4501 C CB  . SER B 1 316 ? 15.89300 6.22600   182.25100 1.000 10.36000 ? 316 SER B CB  1 
ATOM   4502 O OG  . SER B 1 316 ? 17.07500 5.62300   182.75000 1.000 11.39000 ? 316 SER B OG  1 
ATOM   4503 N N   . THR B 1 317 ? 15.16700 2.88400   182.08600 1.000 7.50000  ? 317 THR B N   1 
ATOM   4504 C CA  . THR B 1 317 ? 15.40400 1.67500   181.30400 1.000 7.50000  ? 317 THR B CA  1 
ATOM   4505 C C   . THR B 1 317 ? 14.12200 1.11700   180.70000 1.000 7.35000  ? 317 THR B C   1 
ATOM   4506 O O   . THR B 1 317 ? 14.19900 0.32200   179.75900 1.000 7.56000  ? 317 THR B O   1 
ATOM   4507 C CB  . THR B 1 317 ? 16.10300 0.59600   182.14300 1.000 7.07000  ? 317 THR B CB  1 
ATOM   4508 O OG1 . THR B 1 317 ? 15.30300 0.24500   183.28300 1.000 8.45000  ? 317 THR B OG1 1 
ATOM   4509 C CG2 . THR B 1 317 ? 17.44900 1.09000   182.61800 1.000 7.04000  ? 317 THR B CG2 1 
ATOM   4510 N N   . GLN B 1 318 ? 12.94700 1.50800   181.20300 1.000 6.36000  ? 318 GLN B N   1 
ATOM   4511 C CA  . GLN B 1 318 ? 11.72000 1.11600   180.51500 1.000 7.75000  ? 318 GLN B CA  1 
ATOM   4512 C C   . GLN B 1 318 ? 11.68200 1.70900   179.11400 1.000 8.01000  ? 318 GLN B C   1 
ATOM   4513 O O   . GLN B 1 318 ? 11.30300 1.02900   178.15400 1.000 9.49000  ? 318 GLN B O   1 
ATOM   4514 C CB  . GLN B 1 318 ? 10.48700 1.54600   181.31500 1.000 11.26000 ? 318 GLN B CB  1 
ATOM   4515 C CG  . GLN B 1 318 ? 9.15700  1.28700   180.59100 1.000 9.53000  ? 318 GLN B CG  1 
ATOM   4516 C CD  . GLN B 1 318 ? 8.78400  -0.18500  180.52400 1.000 10.06000 ? 318 GLN B CD  1 
ATOM   4517 O OE1 . GLN B 1 318 ? 9.25000  -0.99600  181.32400 1.000 11.55000 ? 318 GLN B OE1 1 
ATOM   4518 N NE2 . GLN B 1 318 ? 7.92700  -0.53400  179.56900 1.000 9.58000  ? 318 GLN B NE2 1 
ATOM   4519 N N   . ALA B 1 319 ? 12.09700 2.97100   178.97400 1.000 7.03000  ? 319 ALA B N   1 
ATOM   4520 C CA  . ALA B 1 319 ? 12.15100 3.59800   177.65200 1.000 10.77000 ? 319 ALA B CA  1 
ATOM   4521 C C   . ALA B 1 319 ? 13.19100 2.93200   176.75400 1.000 10.32000 ? 319 ALA B C   1 
ATOM   4522 O O   . ALA B 1 319 ? 12.96900 2.80100   175.54400 1.000 9.64000  ? 319 ALA B O   1 
ATOM   4523 C CB  . ALA B 1 319 ? 12.43700 5.09200   177.78600 1.000 11.47000 ? 319 ALA B CB  1 
ATOM   4524 N N   . ASP B 1 320 ? 14.32800 2.50300   177.31800 1.000 8.89000  ? 320 ASP B N   1 
ATOM   4525 C CA  . ASP B 1 320 ? 15.29900 1.73500   176.53200 1.000 8.62000  ? 320 ASP B CA  1 
ATOM   4526 C C   . ASP B 1 320 ? 14.66600 0.46400   175.96900 1.000 6.90000  ? 320 ASP B C   1 
ATOM   4527 O O   . ASP B 1 320 ? 14.81500 0.15300   174.78200 1.000 7.15000  ? 320 ASP B O   1 
ATOM   4528 C CB  . ASP B 1 320 ? 16.53000 1.36800   177.37100 1.000 7.99000  ? 320 ASP B CB  1 
ATOM   4529 C CG  . ASP B 1 320 ? 17.26100 2.57800   177.93300 1.000 11.87000 ? 320 ASP B CG  1 
ATOM   4530 O OD1 . ASP B 1 320 ? 17.37700 3.61600   177.23100 1.000 11.89000 ? 320 ASP B OD1 1 
ATOM   4531 O OD2 . ASP B 1 320 ? 17.73400 2.46700   179.09100 1.000 12.95000 ? 320 ASP B OD2 1 
ATOM   4532 N N   . LEU B 1 321 ? 13.94700 -0.28700  176.80900 1.000 5.56000  ? 321 LEU B N   1 
ATOM   4533 C CA  . LEU B 1 321 ? 13.30600 -1.51000  176.33500 1.000 5.01000  ? 321 LEU B CA  1 
ATOM   4534 C C   . LEU B 1 321 ? 12.29000 -1.20900  175.24000 1.000 7.75000  ? 321 LEU B C   1 
ATOM   4535 O O   . LEU B 1 321 ? 12.18800 -1.94800  174.25100 1.000 6.57000  ? 321 LEU B O   1 
ATOM   4536 C CB  . LEU B 1 321 ? 12.64100 -2.25200  177.50000 1.000 5.84000  ? 321 LEU B CB  1 
ATOM   4537 C CG  . LEU B 1 321 ? 11.84300 -3.49900  177.10200 1.000 7.33000  ? 321 LEU B CG  1 
ATOM   4538 C CD1 . LEU B 1 321 ? 12.73400 -4.57600  176.48200 1.000 8.88000  ? 321 LEU B CD1 1 
ATOM   4539 C CD2 . LEU B 1 321 ? 11.09100 -4.06000  178.30100 1.000 10.06000 ? 321 LEU B CD2 1 
ATOM   4540 N N   . GLU B 1 322 ? 11.53200 -0.12200  175.39000 1.000 7.84000  ? 322 GLU B N   1 
ATOM   4541 C CA  . GLU B 1 322 ? 10.53100 0.19900   174.37400 1.000 8.14000  ? 322 GLU B CA  1 
ATOM   4542 C C   . GLU B 1 322 ? 11.17200 0.55500   173.04000 1.000 8.15000  ? 322 GLU B C   1 
ATOM   4543 O O   . GLU B 1 322 ? 10.56900 0.30900   171.99000 1.000 6.60000  ? 322 GLU B O   1 
ATOM   4544 C CB  . GLU B 1 322 ? 9.62300  1.32400   174.87400 1.000 10.67000 ? 322 GLU B CB  1 
ATOM   4545 C CG  . GLU B 1 322 ? 8.70600  0.83000   176.00400 1.000 10.70000 ? 322 GLU B CG  1 
ATOM   4546 C CD  . GLU B 1 322 ? 7.92500  1.93800   176.68000 1.000 20.46000 ? 322 GLU B CD  1 
ATOM   4547 O OE1 . GLU B 1 322 ? 8.01100  3.10400   176.23000 1.000 22.53000 ? 322 GLU B OE1 1 
ATOM   4548 O OE2 . GLU B 1 322 ? 7.21200  1.63600   177.66200 1.000 14.62000 ? 322 GLU B OE2 1 
ATOM   4549 N N   . ARG B 1 323 ? 12.39000 1.11000   173.05200 1.000 7.12000  ? 323 ARG B N   1 
ATOM   4550 C CA  . ARG B 1 323 ? 13.10900 1.31700   171.79500 1.000 6.65000  ? 323 ARG B CA  1 
ATOM   4551 C C   . ARG B 1 323 ? 13.44500 -0.01400  171.13000 1.000 6.12000  ? 323 ARG B C   1 
ATOM   4552 O O   . ARG B 1 323 ? 13.36500 -0.14800  169.90300 1.000 6.63000  ? 323 ARG B O   1 
ATOM   4553 C CB  . ARG B 1 323 ? 14.38600 2.12400   172.04000 1.000 9.51000  ? 323 ARG B CB  1 
ATOM   4554 C CG  . ARG B 1 323 ? 14.16000 3.55800   172.50200 1.000 8.18000  ? 323 ARG B CG  1 
ATOM   4555 C CD  . ARG B 1 323 ? 15.49100 4.29500   172.65700 1.000 8.18000  ? 323 ARG B CD  1 
ATOM   4556 N NE  . ARG B 1 323 ? 16.17400 4.48800   171.37300 1.000 7.40000  ? 323 ARG B NE  1 
ATOM   4557 C CZ  . ARG B 1 323 ? 17.49300 4.42600   171.21300 1.000 9.07000  ? 323 ARG B CZ  1 
ATOM   4558 N NH1 . ARG B 1 323 ? 18.27000 4.17600   172.25700 1.000 9.46000  ? 323 ARG B NH1 1 
ATOM   4559 N NH2 . ARG B 1 323 ? 18.03700 4.59900   170.00900 1.000 6.09000  ? 323 ARG B NH2 1 
ATOM   4560 N N   . VAL B 1 324 ? 13.85100 -1.00500  171.92100 1.000 5.08000  ? 324 VAL B N   1 
ATOM   4561 C CA  . VAL B 1 324 ? 14.13600 -2.32000  171.35500 1.000 4.27000  ? 324 VAL B CA  1 
ATOM   4562 C C   . VAL B 1 324 ? 12.87200 -2.92100  170.75700 1.000 6.17000  ? 324 VAL B C   1 
ATOM   4563 O O   . VAL B 1 324 ? 12.89100 -3.47400  169.65100 1.000 5.92000  ? 324 VAL B O   1 
ATOM   4564 C CB  . VAL B 1 324 ? 14.74700 -3.23700  172.42800 1.000 5.80000  ? 324 VAL B CB  1 
ATOM   4565 C CG1 . VAL B 1 324 ? 15.05600 -4.61000  171.84200 1.000 5.64000  ? 324 VAL B CG1 1 
ATOM   4566 C CG2 . VAL B 1 324 ? 15.99800 -2.59300  172.99700 1.000 8.94000  ? 324 VAL B CG2 1 
ATOM   4567 N N   . ILE B 1 325 ? 11.75500 -2.80300  171.47400 1.000 5.84000  ? 325 ILE B N   1 
ATOM   4568 C CA  . ILE B 1 325 ? 10.48000 -3.31300  170.97600 1.000 7.42000  ? 325 ILE B CA  1 
ATOM   4569 C C   . ILE B 1 325 ? 10.14200 -2.66900  169.64000 1.000 5.89000  ? 325 ILE B C   1 
ATOM   4570 O O   . ILE B 1 325 ? 9.74400  -3.34600  168.68600 1.000 6.49000  ? 325 ILE B O   1 
ATOM   4571 C CB  . ILE B 1 325 ? 9.36900  -3.06400  172.01100 1.000 9.54000  ? 325 ILE B CB  1 
ATOM   4572 C CG1 . ILE B 1 325 ? 9.61000  -3.90700  173.27000 1.000 10.59000 ? 325 ILE B CG1 1 
ATOM   4573 C CG2 . ILE B 1 325 ? 7.98500  -3.30500  171.38000 1.000 7.86000  ? 325 ILE B CG2 1 
ATOM   4574 C CD1 . ILE B 1 325 ? 9.41000  -5.40500  173.06100 1.000 9.32000  ? 325 ILE B CD1 1 
ATOM   4575 N N   . ALA B 1 326 ? 10.30400 -1.34700  169.54800 1.000 5.68000  ? 326 ALA B N   1 
ATOM   4576 C CA  . ALA B 1 326 ? 9.99200  -0.66300  168.29200 1.000 5.64000  ? 326 ALA B CA  1 
ATOM   4577 C C   . ALA B 1 326 ? 10.90600 -1.12700  167.16400 1.000 5.91000  ? 326 ALA B C   1 
ATOM   4578 O O   . ALA B 1 326 ? 10.47000 -1.24400  166.01200 1.000 6.46000  ? 326 ALA B O   1 
ATOM   4579 C CB  . ALA B 1 326 ? 10.09700 0.85000   168.47000 1.000 6.94000  ? 326 ALA B CB  1 
ATOM   4580 N N   . ALA B 1 327 ? 12.18400 -1.37000  167.47400 1.000 6.21000  ? 327 ALA B N   1 
ATOM   4581 C CA  . ALA B 1 327 ? 13.10400 -1.90900  166.47700 1.000 7.39000  ? 327 ALA B CA  1 
ATOM   4582 C C   . ALA B 1 327 ? 12.65000 -3.28500  166.00000 1.000 6.40000  ? 327 ALA B C   1 
ATOM   4583 O O   . ALA B 1 327 ? 12.71400 -3.58800  164.80300 1.000 5.88000  ? 327 ALA B O   1 
ATOM   4584 C CB  . ALA B 1 327 ? 14.52200 -1.97900  167.05900 1.000 7.20000  ? 327 ALA B CB  1 
ATOM   4585 N N   . MET B 1 328 ? 12.19100 -4.13300  166.92700 1.000 6.41000  ? 328 MET B N   1 
ATOM   4586 C CA  . MET B 1 328 ? 11.69400 -5.45300  166.54400 1.000 5.64000  ? 328 MET B CA  1 
ATOM   4587 C C   . MET B 1 328 ? 10.48700 -5.34500  165.62400 1.000 5.69000  ? 328 MET B C   1 
ATOM   4588 O O   . MET B 1 328 ? 10.39500 -6.06300  164.61700 1.000 5.96000  ? 328 MET B O   1 
ATOM   4589 C CB  . MET B 1 328 ? 11.34000 -6.25500  167.79600 1.000 6.03000  ? 328 MET B CB  1 
ATOM   4590 C CG  . MET B 1 328 ? 12.56500 -6.60600  168.62900 1.000 5.07000  ? 328 MET B CG  1 
ATOM   4591 S SD  . MET B 1 328 ? 12.16100 -7.16200  170.30300 1.000 9.04000  ? 328 MET B SD  1 
ATOM   4592 C CE  . MET B 1 328 ? 11.25900 -8.67800  169.93600 1.000 6.31000  ? 328 MET B CE  1 
ATOM   4593 N N   . GLN B 1 329 ? 9.54400  -4.46000  165.95700 1.000 7.10000  ? 329 GLN B N   1 
ATOM   4594 C CA  . GLN B 1 329 ? 8.36500  -4.28500  165.11300 1.000 6.38000  ? 329 GLN B CA  1 
ATOM   4595 C C   . GLN B 1 329 ? 8.74300  -3.75200  163.73500 1.000 6.84000  ? 329 GLN B C   1 
ATOM   4596 O O   . GLN B 1 329 ? 8.18900  -4.19100  162.71700 1.000 8.23000  ? 329 GLN B O   1 
ATOM   4597 C CB  . GLN B 1 329 ? 7.36700  -3.35400  165.80000 1.000 7.29000  ? 329 GLN B CB  1 
ATOM   4598 C CG  . GLN B 1 329 ? 6.74000  -3.98400  167.04300 1.000 10.05000 ? 329 GLN B CG  1 
ATOM   4599 C CD  . GLN B 1 329 ? 6.05200  -2.97100  167.93800 1.000 21.19000 ? 329 GLN B CD  1 
ATOM   4600 O OE1 . GLN B 1 329 ? 6.37100  -1.77500  167.91700 1.000 23.19000 ? 329 GLN B OE1 1 
ATOM   4601 N NE2 . GLN B 1 329 ? 5.10400  -3.44500  168.74000 1.000 19.71000 ? 329 GLN B NE2 1 
ATOM   4602 N N   . PHE B 1 330 ? 9.70100  -2.82500  163.67800 1.000 6.04000  ? 330 PHE B N   1 
ATOM   4603 C CA  . PHE B 1 330 ? 10.15400 -2.31900  162.38200 1.000 7.06000  ? 330 PHE B CA  1 
ATOM   4604 C C   . PHE B 1 330 ? 10.74200 -3.44000  161.52800 1.000 6.97000  ? 330 PHE B C   1 
ATOM   4605 O O   . PHE B 1 330 ? 10.40200 -3.58500  160.34600 1.000 8.44000  ? 330 PHE B O   1 
ATOM   4606 C CB  . PHE B 1 330 ? 11.17800 -1.18900  162.58700 1.000 7.31000  ? 330 PHE B CB  1 
ATOM   4607 C CG  . PHE B 1 330 ? 12.22500 -1.12300  161.51500 1.000 10.77000 ? 330 PHE B CG  1 
ATOM   4608 C CD1 . PHE B 1 330 ? 11.88700 -0.74800  160.21800 1.000 6.80000  ? 330 PHE B CD1 1 
ATOM   4609 C CD2 . PHE B 1 330 ? 13.54800 -1.44000  161.79700 1.000 8.16000  ? 330 PHE B CD2 1 
ATOM   4610 C CE1 . PHE B 1 330 ? 12.84500 -0.70600  159.21900 1.000 9.16000  ? 330 PHE B CE1 1 
ATOM   4611 C CE2 . PHE B 1 330 ? 14.51400 -1.39800  160.80100 1.000 8.94000  ? 330 PHE B CE2 1 
ATOM   4612 C CZ  . PHE B 1 330 ? 14.16300 -1.02900  159.51400 1.000 9.31000  ? 330 PHE B CZ  1 
ATOM   4613 N N   . MET B 1 331 ? 11.64200 -4.24000  162.10300 1.000 6.21000  ? 331 MET B N   1 
ATOM   4614 C CA  . MET B 1 331 ? 12.28100 -5.28700  161.31200 1.000 6.94000  ? 331 MET B CA  1 
ATOM   4615 C C   . MET B 1 331 ? 11.26600 -6.32200  160.84200 1.000 6.90000  ? 331 MET B C   1 
ATOM   4616 O O   . MET B 1 331 ? 11.32400 -6.77800  159.69600 1.000 9.70000  ? 331 MET B O   1 
ATOM   4617 C CB  . MET B 1 331 ? 13.39500 -5.96000  162.11600 1.000 7.95000  ? 331 MET B CB  1 
ATOM   4618 C CG  . MET B 1 331 ? 14.58600 -5.04700  162.38600 1.000 4.96000  ? 331 MET B CG  1 
ATOM   4619 S SD  . MET B 1 331 ? 15.54900 -4.73300  160.88800 1.000 11.47000 ? 331 MET B SD  1 
ATOM   4620 C CE  . MET B 1 331 ? 16.46900 -6.26900  160.76200 1.000 13.14000 ? 331 MET B CE  1 
ATOM   4621 N N   . LEU B 1 332 ? 10.32500 -6.70500  161.70700 1.000 5.77000  ? 332 LEU B N   1 
ATOM   4622 C CA  . LEU B 1 332 ? 9.36700  -7.74100  161.31800 1.000 8.18000  ? 332 LEU B CA  1 
ATOM   4623 C C   . LEU B 1 332 ? 8.42600  -7.25000  160.22700 1.000 8.62000  ? 332 LEU B C   1 
ATOM   4624 O O   . LEU B 1 332 ? 8.01000  -8.03000  159.36100 1.000 9.57000  ? 332 LEU B O   1 
ATOM   4625 C CB  . LEU B 1 332 ? 8.55600  -8.20500  162.53000 1.000 8.54000  ? 332 LEU B CB  1 
ATOM   4626 C CG  . LEU B 1 332 ? 9.32000  -9.00100  163.58800 1.000 8.45000  ? 332 LEU B CG  1 
ATOM   4627 C CD1 . LEU B 1 332 ? 8.47800  -9.06200  164.86400 1.000 10.33000 ? 332 LEU B CD1 1 
ATOM   4628 C CD2 . LEU B 1 332 ? 9.67200  -10.39600 163.08800 1.000 9.88000  ? 332 LEU B CD2 1 
ATOM   4629 N N   . ALA B 1 333 ? 8.05700  -5.96800  160.26700 1.000 8.12000  ? 333 ALA B N   1 
ATOM   4630 C CA  . ALA B 1 333 ? 7.15000  -5.41700  159.26800 1.000 9.05000  ? 333 ALA B CA  1 
ATOM   4631 C C   . ALA B 1 333 ? 7.84000  -5.12100  157.94000 1.000 11.16000 ? 333 ALA B C   1 
ATOM   4632 O O   . ALA B 1 333 ? 7.15300  -4.92200  156.92700 1.000 8.89000  ? 333 ALA B O   1 
ATOM   4633 C CB  . ALA B 1 333 ? 6.50100  -4.13700  159.80200 1.000 11.16000 ? 333 ALA B CB  1 
ATOM   4634 N N   . ASN B 1 334 ? 9.17100  -5.08000  157.90700 1.000 9.15000  ? 334 ASN B N   1 
ATOM   4635 C CA  . ASN B 1 334 ? 9.90400  -4.62300  156.72200 1.000 9.63000  ? 334 ASN B CA  1 
ATOM   4636 C C   . ASN B 1 334 ? 11.04900 -5.57000  156.38000 1.000 10.76000 ? 334 ASN B C   1 
ATOM   4637 O O   . ASN B 1 334 ? 12.21700 -5.16700  156.33400 1.000 10.32000 ? 334 ASN B O   1 
ATOM   4638 C CB  . ASN B 1 334 ? 10.41000 -3.19900  156.94500 1.000 10.73000 ? 334 ASN B CB  1 
ATOM   4639 C CG  . ASN B 1 334 ? 9.28100  -2.22200  157.17400 1.000 11.80000 ? 334 ASN B CG  1 
ATOM   4640 O OD1 . ASN B 1 334 ? 8.71400  -1.68100  156.22300 1.000 13.06000 ? 334 ASN B OD1 1 
ATOM   4641 N ND2 . ASN B 1 334 ? 8.91900  -2.01500  158.43200 1.000 8.67000  ? 334 ASN B ND2 1 
ATOM   4642 N N   . PRO B 1 335 ? 10.74700 -6.83800  156.09800 1.000 9.93000  ? 335 PRO B N   1 
ATOM   4643 C CA  . PRO B 1 335 ? 11.82000 -7.79900  155.82300 1.000 10.86000 ? 335 PRO B CA  1 
ATOM   4644 C C   . PRO B 1 335 ? 12.47900 -7.55300  154.47300 1.000 10.92000 ? 335 PRO B C   1 
ATOM   4645 O O   . PRO B 1 335 ? 11.87200 -7.01100  153.54800 1.000 12.30000 ? 335 PRO B O   1 
ATOM   4646 C CB  . PRO B 1 335 ? 11.09800 -9.15100  155.84300 1.000 13.83000 ? 335 PRO B CB  1 
ATOM   4647 C CG  . PRO B 1 335 ? 9.70600  -8.82200  155.40800 1.000 15.30000 ? 335 PRO B CG  1 
ATOM   4648 C CD  . PRO B 1 335 ? 9.41200  -7.45400  155.98500 1.000 12.80000 ? 335 PRO B CD  1 
ATOM   4649 N N   . ALA B 1 336 ? 13.72600 -7.99600  154.36500 1.000 11.87000 ? 336 ALA B N   1 
ATOM   4650 C CA  . ALA B 1 336 ? 14.52100 -7.80400  153.14500 1.000 14.98000 ? 336 ALA B CA  1 
ATOM   4651 C C   . ALA B 1 336 ? 13.85900 -8.42400  151.91300 1.000 26.18000 ? 336 ALA B C   1 
ATOM   4652 O O   . ALA B 1 336 ? 13.20800 -9.47000  152.00300 1.000 24.43000 ? 336 ALA B O   1 
ATOM   4653 C CB  . ALA B 1 336 ? 15.92400 -8.38400  153.33300 1.000 12.48000 ? 336 ALA B CB  1 
HETATM 4654 O O1  . MES C 2 .   ? 30.66300 8.24900   144.20600 1.000 34.14000 ? 401 MES A O1  1 
HETATM 4655 C C2  . MES C 2 .   ? 30.27900 9.60600   144.25600 1.000 18.73000 ? 401 MES A C2  1 
HETATM 4656 C C3  . MES C 2 .   ? 28.84400 9.85400   143.79100 1.000 5.68000  ? 401 MES A C3  1 
HETATM 4657 N N4  . MES C 2 .   ? 28.34500 8.97400   142.73400 1.000 24.32000 ? 401 MES A N4  1 
HETATM 4658 C C5  . MES C 2 .   ? 28.95700 7.66200   142.59300 1.000 9.54000  ? 401 MES A C5  1 
HETATM 4659 C C6  . MES C 2 .   ? 30.44200 7.75800   142.89500 1.000 21.48000 ? 401 MES A C6  1 
HETATM 4660 C C7  . MES C 2 .   ? 26.94600 9.17500   142.30200 1.000 8.86000  ? 401 MES A C7  1 
HETATM 4661 C C8  . MES C 2 .   ? 26.80900 9.30400   140.78200 1.000 27.75000 ? 401 MES A C8  1 
HETATM 4662 S S   . MES C 2 .   ? 26.52000 7.92200   139.90000 1.000 57.32000 ? 401 MES A S   1 
HETATM 4663 O O1S . MES C 2 .   ? 25.09500 7.50200   139.92200 1.000 57.05000 ? 401 MES A O1S 1 
HETATM 4664 O O2S . MES C 2 .   ? 27.32900 6.80000   140.41900 1.000 26.87000 ? 401 MES A O2S 1 
HETATM 4665 O O3S . MES C 2 .   ? 26.90100 8.24100   138.49600 1.000 33.29000 ? 401 MES A O3S 1 
HETATM 4666 O O1  . MES D 2 .   ? 28.01500 -12.88700 180.94900 1.000 35.18000 ? 401 MES B O1  1 
HETATM 4667 C C2  . MES D 2 .   ? 27.18800 -13.98500 181.27300 1.000 23.18000 ? 401 MES B C2  1 
HETATM 4668 C C3  . MES D 2 .   ? 25.69200 -13.67500 181.17000 1.000 9.45000  ? 401 MES B C3  1 
HETATM 4669 N N4  . MES D 2 .   ? 25.29400 -12.42000 181.78300 1.000 25.51000 ? 401 MES B N4  1 
HETATM 4670 C C5  . MES D 2 .   ? 26.39600 -11.81200 182.50100 1.000 8.51000  ? 401 MES B C5  1 
HETATM 4671 C C6  . MES D 2 .   ? 27.65600 -11.70000 181.65600 1.000 19.31000 ? 401 MES B C6  1 
HETATM 4672 C C7  . MES D 2 .   ? 24.13700 -12.69800 182.63800 1.000 9.23000  ? 401 MES B C7  1 
HETATM 4673 C C8  . MES D 2 .   ? 23.44100 -11.49400 183.28200 1.000 25.08000 ? 401 MES B C8  1 
HETATM 4674 S S   . MES D 2 .   ? 23.93900 -11.06100 184.81300 1.000 45.26000 ? 401 MES B S   1 
HETATM 4675 O O1S . MES D 2 .   ? 25.25800 -10.39900 184.71600 1.000 19.30000 ? 401 MES B O1S 1 
HETATM 4676 O O2S . MES D 2 .   ? 23.99600 -12.19900 185.77100 1.000 34.94000 ? 401 MES B O2S 1 
HETATM 4677 O O3S . MES D 2 .   ? 22.97600 -10.05600 185.32800 1.000 48.38000 ? 401 MES B O3S 1 
HETATM 4678 O O   . HOH E 3 .   ? 36.25000 -5.08100  138.93300 1.000 31.28000 ? 501 HOH A O   1 
HETATM 4679 O O   . HOH E 3 .   ? 29.54600 0.93800   121.21600 1.000 32.50000 ? 502 HOH A O   1 
HETATM 4680 O O   . HOH E 3 .   ? 22.95300 19.89100  135.58200 1.000 16.68000 ? 503 HOH A O   1 
HETATM 4681 O O   . HOH E 3 .   ? 36.09700 9.18400   171.48800 1.000 35.29000 ? 504 HOH A O   1 
HETATM 4682 O O   . HOH E 3 .   ? 26.87100 22.31500  133.04000 1.000 23.05000 ? 505 HOH A O   1 
HETATM 4683 O O   . HOH E 3 .   ? 18.42700 -11.24100 132.26400 1.000 31.33000 ? 506 HOH A O   1 
HETATM 4684 O O   . HOH E 3 .   ? 19.98800 -14.99400 134.74600 1.000 37.22000 ? 507 HOH A O   1 
HETATM 4685 O O   . HOH E 3 .   ? 1.97100  11.24000  158.61200 1.000 31.21000 ? 508 HOH A O   1 
HETATM 4686 O O   . HOH E 3 .   ? 10.17700 30.57800  146.12400 1.000 30.81000 ? 509 HOH A O   1 
HETATM 4687 O O   . HOH E 3 .   ? 11.79600 28.13800  157.68800 1.000 15.22000 ? 510 HOH A O   1 
HETATM 4688 O O   . HOH E 3 .   ? 30.81800 -10.22900 138.87800 1.000 26.50000 ? 511 HOH A O   1 
HETATM 4689 O O   . HOH E 3 .   ? 17.40200 20.05500  134.17100 1.000 23.34000 ? 512 HOH A O   1 
HETATM 4690 O O   . HOH E 3 .   ? 27.16500 27.70000  144.75800 1.000 20.25000 ? 513 HOH A O   1 
HETATM 4691 O O   . HOH E 3 .   ? 19.14900 10.21000  175.38600 1.000 34.01000 ? 514 HOH A O   1 
HETATM 4692 O O   . HOH E 3 .   ? 38.09500 9.51500   163.48900 1.000 21.06000 ? 515 HOH A O   1 
HETATM 4693 O O   . HOH E 3 .   ? 21.51600 7.49000   143.00000 1.000 13.15000 ? 516 HOH A O   1 
HETATM 4694 O O   . HOH E 3 .   ? 3.39000  21.78100  143.39300 1.000 19.05000 ? 517 HOH A O   1 
HETATM 4695 O O   . HOH E 3 .   ? 38.79300 23.67400  138.23000 1.000 22.22000 ? 518 HOH A O   1 
HETATM 4696 O O   . HOH E 3 .   ? 36.90500 25.11500  145.37000 1.000 14.65000 ? 519 HOH A O   1 
HETATM 4697 O O   . HOH E 3 .   ? 23.20200 31.51800  154.64800 1.000 17.77000 ? 520 HOH A O   1 
HETATM 4698 O O   . HOH E 3 .   ? 14.54100 21.65000  168.56600 1.000 23.49000 ? 521 HOH A O   1 
HETATM 4699 O O   . HOH E 3 .   ? 0.86800  12.67900  144.76500 1.000 22.92000 ? 522 HOH A O   1 
HETATM 4700 O O   . HOH E 3 .   ? 7.48400  -0.48900  133.77500 1.000 31.13000 ? 523 HOH A O   1 
HETATM 4701 O O   . HOH E 3 .   ? 6.64000  24.41200  160.11300 1.000 16.00000 ? 524 HOH A O   1 
HETATM 4702 O O   . HOH E 3 .   ? -0.54300 13.93600  157.21500 1.000 26.43000 ? 525 HOH A O   1 
HETATM 4703 O O   . HOH E 3 .   ? 41.77300 8.75000   152.96900 1.000 20.36000 ? 526 HOH A O   1 
HETATM 4704 O O   . HOH E 3 .   ? 31.20800 26.43500  159.79200 1.000 15.34000 ? 527 HOH A O   1 
HETATM 4705 O O   . HOH E 3 .   ? 7.42900  32.91700  156.74900 1.000 31.56000 ? 528 HOH A O   1 
HETATM 4706 O O   . HOH E 3 .   ? 9.10200  -2.99700  144.83700 1.000 21.47000 ? 529 HOH A O   1 
HETATM 4707 O O   . HOH E 3 .   ? 34.22400 16.18600  158.24600 1.000 10.59000 ? 530 HOH A O   1 
HETATM 4708 O O   . HOH E 3 .   ? 6.76700  9.66700   158.74100 1.000 26.28000 ? 531 HOH A O   1 
HETATM 4709 O O   . HOH E 3 .   ? 39.97600 3.25600   152.94300 1.000 22.62000 ? 532 HOH A O   1 
HETATM 4710 O O   . HOH E 3 .   ? 30.63000 10.54900  161.96800 1.000 6.68000  ? 533 HOH A O   1 
HETATM 4711 O O   . HOH E 3 .   ? 17.62700 -6.83700  129.47100 1.000 21.91000 ? 534 HOH A O   1 
HETATM 4712 O O   . HOH E 3 .   ? 24.45400 14.40700  158.93500 1.000 4.58000  ? 535 HOH A O   1 
HETATM 4713 O O   . HOH E 3 .   ? 32.80500 25.56500  157.42200 1.000 20.63000 ? 536 HOH A O   1 
HETATM 4714 O O   . HOH E 3 .   ? 42.34000 16.51500  141.12300 1.000 23.75000 ? 537 HOH A O   1 
HETATM 4715 O O   . HOH E 3 .   ? 27.93700 26.90200  165.91200 1.000 22.46000 ? 538 HOH A O   1 
HETATM 4716 O O   . HOH E 3 .   ? 25.91000 4.60100   139.51100 1.000 20.01000 ? 539 HOH A O   1 
HETATM 4717 O O   . HOH E 3 .   ? 24.46700 20.64300  142.54300 1.000 8.61000  ? 540 HOH A O   1 
HETATM 4718 O O   . HOH E 3 .   ? 38.19200 -0.90500  165.14600 1.000 35.47000 ? 541 HOH A O   1 
HETATM 4719 O O   . HOH E 3 .   ? 21.18800 4.95900   172.35900 1.000 9.53000  ? 542 HOH A O   1 
HETATM 4720 O O   . HOH E 3 .   ? 9.05400  18.35800  166.00400 1.000 19.59000 ? 543 HOH A O   1 
HETATM 4721 O O   . HOH E 3 .   ? 27.14000 -1.01800  141.74800 1.000 8.96000  ? 544 HOH A O   1 
HETATM 4722 O O   . HOH E 3 .   ? 0.38100  20.46800  158.64000 1.000 17.09000 ? 545 HOH A O   1 
HETATM 4723 O O   . HOH E 3 .   ? 15.17000 27.16300  163.98800 1.000 17.83000 ? 546 HOH A O   1 
HETATM 4724 O O   . HOH E 3 .   ? 29.59100 4.82200   135.89400 1.000 19.43000 ? 547 HOH A O   1 
HETATM 4725 O O   . HOH E 3 .   ? 25.03600 -9.64100  146.11400 1.000 9.07000  ? 548 HOH A O   1 
HETATM 4726 O O   . HOH E 3 .   ? 15.57000 -5.25600  150.55800 1.000 9.37000  ? 549 HOH A O   1 
HETATM 4727 O O   . HOH E 3 .   ? 5.87800  23.27500  153.63400 1.000 27.80000 ? 550 HOH A O   1 
HETATM 4728 O O   . HOH E 3 .   ? 35.75600 -0.41800  162.52200 1.000 12.97000 ? 551 HOH A O   1 
HETATM 4729 O O   . HOH E 3 .   ? 14.60000 -4.87500  134.80200 1.000 15.23000 ? 552 HOH A O   1 
HETATM 4730 O O   . HOH E 3 .   ? 28.35400 20.35600  125.14900 1.000 25.26000 ? 553 HOH A O   1 
HETATM 4731 O O   . HOH E 3 .   ? 4.96400  13.13900  137.36100 1.000 26.07000 ? 554 HOH A O   1 
HETATM 4732 O O   . HOH E 3 .   ? 30.82200 -1.63500  137.89200 1.000 12.89000 ? 555 HOH A O   1 
HETATM 4733 O O   . HOH E 3 .   ? 31.77400 13.39100  172.12500 1.000 25.67000 ? 556 HOH A O   1 
HETATM 4734 O O   . HOH E 3 .   ? 16.14600 4.66600   167.82800 1.000 17.15000 ? 557 HOH A O   1 
HETATM 4735 O O   . HOH E 3 .   ? 30.968   21.933    170.114   1.000 23.60000 ? 558 HOH A O   1 
HETATM 4736 O O   . HOH E 3 .   ? 28.34200 2.40200   133.45800 1.000 27.45000 ? 559 HOH A O   1 
HETATM 4737 O O   . HOH E 3 .   ? 32.45400 21.04600  144.66900 1.000 9.53000  ? 560 HOH A O   1 
HETATM 4738 O O   . HOH E 3 .   ? 9.90600  3.71900   172.39900 1.000 24.39000 ? 561 HOH A O   1 
HETATM 4739 O O   . HOH E 3 .   ? 30.859   26.922    162.562   1.000 19.63000 ? 562 HOH A O   1 
HETATM 4740 O O   . HOH E 3 .   ? 23.23300 26.76300  143.45300 1.000 11.38000 ? 563 HOH A O   1 
HETATM 4741 O O   . HOH E 3 .   ? 19.54900 18.36800  134.51400 1.000 18.78000 ? 564 HOH A O   1 
HETATM 4742 O O   . HOH E 3 .   ? 24.92300 -8.41800  151.11900 1.000 14.82000 ? 565 HOH A O   1 
HETATM 4743 O O   . HOH E 3 .   ? 44.87100 16.77600  156.13600 1.000 27.69000 ? 566 HOH A O   1 
HETATM 4744 O O   . HOH E 3 .   ? 38.93500 4.25300   139.86500 1.000 24.65000 ? 567 HOH A O   1 
HETATM 4745 O O   . HOH E 3 .   ? 32.75300 6.77700   132.90000 1.000 17.79000 ? 568 HOH A O   1 
HETATM 4746 O O   . HOH E 3 .   ? 28.91100 25.30200  135.18700 1.000 19.58000 ? 569 HOH A O   1 
HETATM 4747 O O   . HOH E 3 .   ? 38.02100 -5.76400  153.60700 1.000 36.38000 ? 570 HOH A O   1 
HETATM 4748 O O   . HOH E 3 .   ? 35.65800 27.90200  141.14800 1.000 21.27000 ? 571 HOH A O   1 
HETATM 4749 O O   . HOH E 3 .   ? 24.47200 5.03700   171.18000 1.000 6.81000  ? 572 HOH A O   1 
HETATM 4750 O O   . HOH E 3 .   ? 20.31000 7.12600   168.22800 1.000 14.33000 ? 573 HOH A O   1 
HETATM 4751 O O   . HOH E 3 .   ? 18.10000 11.48600  172.20700 1.000 19.87000 ? 574 HOH A O   1 
HETATM 4752 O O   . HOH E 3 .   ? 15.99200 17.28100  143.63000 1.000 11.03000 ? 575 HOH A O   1 
HETATM 4753 O O   . HOH E 3 .   ? 5.48600  7.68600   140.83700 1.000 17.36000 ? 576 HOH A O   1 
HETATM 4754 O O   . HOH E 3 .   ? 27.14300 18.75100  169.03200 1.000 19.20000 ? 577 HOH A O   1 
HETATM 4755 O O   . HOH E 3 .   ? 11.43300 9.89200   136.87800 1.000 13.94000 ? 578 HOH A O   1 
HETATM 4756 O O   . HOH E 3 .   ? 13.42000 26.28800  165.77300 1.000 28.26000 ? 579 HOH A O   1 
HETATM 4757 O O   . HOH E 3 .   ? 10.68000 5.36500   133.80200 1.000 18.86000 ? 580 HOH A O   1 
HETATM 4758 O O   . HOH E 3 .   ? 4.97000  0.31900   146.67500 1.000 24.33000 ? 581 HOH A O   1 
HETATM 4759 O O   . HOH E 3 .   ? 27.59100 5.78400   137.58000 1.000 36.28000 ? 582 HOH A O   1 
HETATM 4760 O O   . HOH E 3 .   ? 17.12900 -11.37100 134.53600 1.000 18.34000 ? 583 HOH A O   1 
HETATM 4761 O O   . HOH E 3 .   ? 2.12400  11.88800  151.75000 1.000 16.14000 ? 584 HOH A O   1 
HETATM 4762 O O   . HOH E 3 .   ? 32.57800 16.50400  164.42800 1.000 7.41000  ? 585 HOH A O   1 
HETATM 4763 O O   . HOH E 3 .   ? 16.61300 -9.88600  146.96000 1.000 18.07000 ? 586 HOH A O   1 
HETATM 4764 O O   . HOH E 3 .   ? 41.55600 12.06900  161.38900 1.000 11.35000 ? 587 HOH A O   1 
HETATM 4765 O O   . HOH E 3 .   ? 27.37300 6.98800   128.79500 1.000 36.58000 ? 588 HOH A O   1 
HETATM 4766 O O   . HOH E 3 .   ? 5.10200  16.71000  140.45400 1.000 15.49000 ? 589 HOH A O   1 
HETATM 4767 O O   . HOH E 3 .   ? 37.51100 -3.98300  151.75700 1.000 17.43000 ? 590 HOH A O   1 
HETATM 4768 O O   . HOH E 3 .   ? 22.35400 7.79600   140.56200 1.000 15.66000 ? 591 HOH A O   1 
HETATM 4769 O O   . HOH E 3 .   ? 35.51800 16.31000  128.18000 1.000 33.38000 ? 592 HOH A O   1 
HETATM 4770 O O   . HOH E 3 .   ? 23.95200 -7.12500  127.24100 1.000 22.56000 ? 593 HOH A O   1 
HETATM 4771 O O   . HOH E 3 .   ? 24.01400 29.48600  156.32700 1.000 10.56000 ? 594 HOH A O   1 
HETATM 4772 O O   . HOH E 3 .   ? 29.81100 26.49200  154.84400 1.000 9.72000  ? 595 HOH A O   1 
HETATM 4773 O O   . HOH E 3 .   ? 32.66000 15.33400  131.29600 1.000 15.75000 ? 596 HOH A O   1 
HETATM 4774 O O   . HOH E 3 .   ? 7.77100  2.14100   154.45600 1.000 10.17000 ? 597 HOH A O   1 
HETATM 4775 O O   . HOH E 3 .   ? 35.24800 13.06400  148.76400 1.000 18.27000 ? 598 HOH A O   1 
HETATM 4776 O O   . HOH E 3 .   ? 16.56700 8.77500   166.72900 1.000 10.72000 ? 599 HOH A O   1 
HETATM 4777 O O   . HOH E 3 .   ? 30.97000 14.29100  164.62100 1.000 7.36000  ? 600 HOH A O   1 
HETATM 4778 O O   . HOH E 3 .   ? 35.11200 5.01000   165.65400 1.000 11.03000 ? 601 HOH A O   1 
HETATM 4779 O O   . HOH E 3 .   ? 7.16700  17.72700  139.20600 1.000 20.37000 ? 602 HOH A O   1 
HETATM 4780 O O   . HOH E 3 .   ? 13.23300 32.30700  162.47000 1.000 28.39000 ? 603 HOH A O   1 
HETATM 4781 O O   . HOH E 3 .   ? 15.95000 26.67900  142.89000 1.000 15.44000 ? 604 HOH A O   1 
HETATM 4782 O O   . HOH E 3 .   ? 9.94800  11.37700  168.52800 1.000 22.38000 ? 605 HOH A O   1 
HETATM 4783 O O   . HOH E 3 .   ? 42.48700 19.63300  152.46000 1.000 17.10000 ? 606 HOH A O   1 
HETATM 4784 O O   . HOH E 3 .   ? 5.314    3.609     138.163   1.000 37.98000 ? 607 HOH A O   1 
HETATM 4785 O O   . HOH E 3 .   ? 5.23400  5.82700   154.17500 1.000 14.85000 ? 608 HOH A O   1 
HETATM 4786 O O   . HOH E 3 .   ? 8.27300  8.56400   162.98300 1.000 9.31000  ? 609 HOH A O   1 
HETATM 4787 O O   . HOH E 3 .   ? 27.21700 15.22400  142.66200 1.000 7.66000  ? 610 HOH A O   1 
HETATM 4788 O O   . HOH E 3 .   ? 43.20100 7.09800   151.56100 1.000 24.14000 ? 611 HOH A O   1 
HETATM 4789 O O   . HOH E 3 .   ? 8.67700  2.30700   160.98400 1.000 10.82000 ? 612 HOH A O   1 
HETATM 4790 O O   . HOH E 3 .   ? 34.06300 1.50600   131.90200 1.000 36.10000 ? 613 HOH A O   1 
HETATM 4791 O O   . HOH E 3 .   ? 22.69400 30.27600  142.52100 1.000 29.52000 ? 614 HOH A O   1 
HETATM 4792 O O   . HOH E 3 .   ? 27.55600 -1.40200  134.08000 1.000 22.08000 ? 615 HOH A O   1 
HETATM 4793 O O   . HOH E 3 .   ? 33.71700 15.82600  150.37400 1.000 7.82000  ? 616 HOH A O   1 
HETATM 4794 O O   . HOH E 3 .   ? 5.85100  6.45500   143.28300 1.000 23.71000 ? 617 HOH A O   1 
HETATM 4795 O O   . HOH E 3 .   ? 10.63300 -6.83400  140.01500 1.000 21.24000 ? 618 HOH A O   1 
HETATM 4796 O O   . HOH E 3 .   ? -0.87800 24.84100  149.66900 1.000 13.30000 ? 619 HOH A O   1 
HETATM 4797 O O   . HOH E 3 .   ? 30.11000 24.73300  139.89700 1.000 15.42000 ? 620 HOH A O   1 
HETATM 4798 O O   . HOH E 3 .   ? 40.62500 -2.50400  145.18900 1.000 20.69000 ? 621 HOH A O   1 
HETATM 4799 O O   . HOH E 3 .   ? 9.44200  -2.75200  151.47100 1.000 18.58000 ? 622 HOH A O   1 
HETATM 4800 O O   . HOH E 3 .   ? 21.59600 27.55700  162.09200 1.000 10.22000 ? 623 HOH A O   1 
HETATM 4801 O O   . HOH E 3 .   ? 27.80200 29.66300  147.78700 1.000 14.77000 ? 624 HOH A O   1 
HETATM 4802 O O   . HOH E 3 .   ? 17.09700 32.85600  159.23800 1.000 28.50000 ? 625 HOH A O   1 
HETATM 4803 O O   . HOH E 3 .   ? 27.93000 13.01400  160.60900 1.000 6.04000  ? 626 HOH A O   1 
HETATM 4804 O O   . HOH E 3 .   ? 38.46700 10.45900  127.85900 1.000 33.89000 ? 627 HOH A O   1 
HETATM 4805 O O   . HOH E 3 .   ? 26.61300 30.32400  145.20200 1.000 20.24000 ? 628 HOH A O   1 
HETATM 4806 O O   . HOH E 3 .   ? 32.73900 6.64500   172.09200 1.000 28.14000 ? 629 HOH A O   1 
HETATM 4807 O O   . HOH E 3 .   ? 38.47700 8.02600   134.12500 1.000 18.72000 ? 630 HOH A O   1 
HETATM 4808 O O   . HOH E 3 .   ? 13.42900 11.25800  136.86000 1.000 21.63000 ? 631 HOH A O   1 
HETATM 4809 O O   . HOH E 3 .   ? 6.19800  27.96200  160.59000 1.000 28.36000 ? 632 HOH A O   1 
HETATM 4810 O O   . HOH E 3 .   ? 15.45400 9.49900   129.29800 1.000 16.36000 ? 633 HOH A O   1 
HETATM 4811 O O   . HOH E 3 .   ? 39.51400 20.01800  139.41100 1.000 23.12000 ? 634 HOH A O   1 
HETATM 4812 O O   . HOH E 3 .   ? 31.23200 24.45500  132.61200 1.000 25.13000 ? 635 HOH A O   1 
HETATM 4813 O O   . HOH E 3 .   ? 38.71300 13.93700  163.07500 1.000 13.70000 ? 636 HOH A O   1 
HETATM 4814 O O   . HOH E 3 .   ? 7.02000  8.50000   169.23600 1.000 35.39000 ? 637 HOH A O   1 
HETATM 4815 O O   . HOH E 3 .   ? 23.16900 21.34900  164.63900 1.000 6.98000  ? 638 HOH A O   1 
HETATM 4816 O O   . HOH E 3 .   ? 43.48100 12.66000  158.91800 1.000 19.89000 ? 639 HOH A O   1 
HETATM 4817 O O   . HOH E 3 .   ? 14.79900 10.97300  174.26700 1.000 35.28000 ? 640 HOH A O   1 
HETATM 4818 O O   . HOH E 3 .   ? 35.58400 1.23000   160.27400 1.000 10.91000 ? 641 HOH A O   1 
HETATM 4819 O O   . HOH E 3 .   ? 37.60200 26.15700  137.72000 1.000 12.30000 ? 642 HOH A O   1 
HETATM 4820 O O   . HOH E 3 .   ? 5.61900  27.20700  164.45100 1.000 35.28000 ? 643 HOH A O   1 
HETATM 4821 O O   . HOH E 3 .   ? 25.38500 16.63200  163.83300 1.000 7.62000  ? 644 HOH A O   1 
HETATM 4822 O O   . HOH E 3 .   ? 41.58900 10.06600  139.22200 1.000 24.73000 ? 645 HOH A O   1 
HETATM 4823 O O   . HOH E 3 .   ? 26.76500 -5.28200  132.98800 1.000 22.14000 ? 646 HOH A O   1 
HETATM 4824 O O   . HOH E 3 .   ? 9.58400  29.77700  163.18100 1.000 31.52000 ? 647 HOH A O   1 
HETATM 4825 O O   . HOH E 3 .   ? 21.50800 22.72800  167.90800 1.000 12.66000 ? 648 HOH A O   1 
HETATM 4826 O O   . HOH E 3 .   ? 39.57100 7.22800   153.80600 1.000 12.20000 ? 649 HOH A O   1 
HETATM 4827 O O   . HOH E 3 .   ? 12.94500 17.19300  165.37400 1.000 15.62000 ? 650 HOH A O   1 
HETATM 4828 O O   . HOH E 3 .   ? 19.36400 -13.30000 138.66000 1.000 24.40000 ? 651 HOH A O   1 
HETATM 4829 O O   . HOH E 3 .   ? 32.45000 17.28900  167.11300 1.000 9.59000  ? 652 HOH A O   1 
HETATM 4830 O O   . HOH E 3 .   ? 24.19100 7.52600   166.43300 1.000 10.37000 ? 653 HOH A O   1 
HETATM 4831 O O   . HOH E 3 .   ? 5.37400  18.04700  160.48500 1.000 18.98000 ? 654 HOH A O   1 
HETATM 4832 O O   . HOH E 3 .   ? 37.61000 7.49300   131.73900 1.000 24.47000 ? 655 HOH A O   1 
HETATM 4833 O O   . HOH E 3 .   ? 3.27500  22.60000  153.46100 1.000 19.09000 ? 656 HOH A O   1 
HETATM 4834 O O   . HOH E 3 .   ? 20.34400 17.88100  146.19400 1.000 5.53000  ? 657 HOH A O   1 
HETATM 4835 O O   . HOH E 3 .   ? 18.18200 8.45100   168.83800 1.000 10.10000 ? 658 HOH A O   1 
HETATM 4836 O O   . HOH E 3 .   ? 25.86000 -3.12200  132.47700 1.000 20.99000 ? 659 HOH A O   1 
HETATM 4837 O O   . HOH E 3 .   ? 26.28800 -10.66000 139.53200 1.000 26.08000 ? 660 HOH A O   1 
HETATM 4838 O O   . HOH E 3 .   ? 28.71900 2.70700   150.31500 1.000 7.01000  ? 661 HOH A O   1 
HETATM 4839 O O   . HOH E 3 .   ? 6.43900  26.44900  153.48000 1.000 39.21000 ? 662 HOH A O   1 
HETATM 4840 O O   . HOH E 3 .   ? 32.64300 -9.94900  140.94700 1.000 26.95000 ? 663 HOH A O   1 
HETATM 4841 O O   . HOH E 3 .   ? 25.65400 15.16800  166.23500 1.000 10.30000 ? 664 HOH A O   1 
HETATM 4842 O O   . HOH E 3 .   ? 31.59900 -1.53000  132.93700 1.000 22.47000 ? 665 HOH A O   1 
HETATM 4843 O O   . HOH E 3 .   ? 0.29700  15.05200  148.72400 1.000 17.02000 ? 666 HOH A O   1 
HETATM 4844 O O   . HOH E 3 .   ? 18.79700 15.26100  129.25500 1.000 8.20000  ? 667 HOH A O   1 
HETATM 4845 O O   . HOH E 3 .   ? 26.96500 0.87900   148.89300 1.000 8.00000  ? 668 HOH A O   1 
HETATM 4846 O O   . HOH E 3 .   ? 40.43600 20.47000  145.45800 1.000 14.41000 ? 669 HOH A O   1 
HETATM 4847 O O   . HOH E 3 .   ? 29.20300 -2.53600  127.14000 1.000 32.79000 ? 670 HOH A O   1 
HETATM 4848 O O   . HOH E 3 .   ? 24.63800 -16.04300 142.01700 1.000 30.40000 ? 671 HOH A O   1 
HETATM 4849 O O   . HOH E 3 .   ? 6.72700  2.33300   159.22400 1.000 23.48000 ? 672 HOH A O   1 
HETATM 4850 O O   . HOH E 3 .   ? 23.21300 16.43300  135.99400 1.000 8.29000  ? 673 HOH A O   1 
HETATM 4851 O O   . HOH E 3 .   ? 2.78900  26.01800  155.49200 1.000 22.13000 ? 674 HOH A O   1 
HETATM 4852 O O   . HOH E 3 .   ? 14.98400 23.21700  136.98500 1.000 33.59000 ? 675 HOH A O   1 
HETATM 4853 O O   . HOH E 3 .   ? 38.48300 13.57500  145.15700 1.000 15.39000 ? 676 HOH A O   1 
HETATM 4854 O O   . HOH E 3 .   ? 37.81700 14.66100  135.80800 1.000 14.48000 ? 677 HOH A O   1 
HETATM 4855 O O   . HOH E 3 .   ? 13.35000 16.02600  132.35900 1.000 24.17000 ? 678 HOH A O   1 
HETATM 4856 O O   . HOH E 3 .   ? 8.88800  8.55700   142.43000 1.000 10.52000 ? 679 HOH A O   1 
HETATM 4857 O O   . HOH E 3 .   ? 1.00300  13.97700  153.55600 1.000 19.03000 ? 680 HOH A O   1 
HETATM 4858 O O   . HOH E 3 .   ? 8.93500  12.54000  136.62400 1.000 27.26000 ? 681 HOH A O   1 
HETATM 4859 O O   . HOH E 3 .   ? 13.48700 12.26300  166.69300 1.000 11.46000 ? 682 HOH A O   1 
HETATM 4860 O O   . HOH E 3 .   ? 5.26300  13.13100  159.60100 1.000 17.03000 ? 683 HOH A O   1 
HETATM 4861 O O   . HOH E 3 .   ? 6.18500  26.33300  142.24800 1.000 28.85000 ? 684 HOH A O   1 
HETATM 4862 O O   . HOH E 3 .   ? 12.19000 6.85700   172.43300 1.000 16.71000 ? 685 HOH A O   1 
HETATM 4863 O O   . HOH E 3 .   ? 0.42300  26.94800  153.15500 1.000 28.38000 ? 686 HOH A O   1 
HETATM 4864 O O   . HOH E 3 .   ? 31.46900 35.04100  144.80500 1.000 37.26000 ? 687 HOH A O   1 
HETATM 4865 O O   . HOH E 3 .   ? 34.06600 12.50300  143.93300 1.000 21.19000 ? 688 HOH A O   1 
HETATM 4866 O O   . HOH E 3 .   ? 28.89300 15.71400  120.72000 1.000 40.91000 ? 689 HOH A O   1 
HETATM 4867 O O   . HOH E 3 .   ? 9.85800  -2.40000  134.64900 1.000 30.37000 ? 690 HOH A O   1 
HETATM 4868 O O   . HOH E 3 .   ? 35.06400 8.52400   132.56000 1.000 17.96000 ? 691 HOH A O   1 
HETATM 4869 O O   . HOH E 3 .   ? 35.98600 -1.84700  157.32500 1.000 28.10000 ? 692 HOH A O   1 
HETATM 4870 O O   . HOH E 3 .   ? 17.84800 -7.00100  150.56200 1.000 9.84000  ? 693 HOH A O   1 
HETATM 4871 O O   . HOH E 3 .   ? 3.21700  9.22400   154.31800 1.000 20.32000 ? 694 HOH A O   1 
HETATM 4872 O O   . HOH E 3 .   ? 4.11600  24.34600  144.62800 1.000 18.42000 ? 695 HOH A O   1 
HETATM 4873 O O   . HOH E 3 .   ? 13.15800 25.50500  158.11400 1.000 23.04000 ? 696 HOH A O   1 
HETATM 4874 O O   . HOH E 3 .   ? 13.81600 34.96000  158.69600 1.000 27.01000 ? 697 HOH A O   1 
HETATM 4875 O O   . HOH E 3 .   ? 35.03600 17.74300  168.15100 1.000 12.53000 ? 698 HOH A O   1 
HETATM 4876 O O   . HOH E 3 .   ? 18.61700 17.26000  144.07900 1.000 8.83000  ? 699 HOH A O   1 
HETATM 4877 O O   . HOH E 3 .   ? 36.30400 0.96600   169.83600 1.000 30.26000 ? 700 HOH A O   1 
HETATM 4878 O O   . HOH E 3 .   ? 34.43500 -6.85800  151.57000 1.000 26.79000 ? 701 HOH A O   1 
HETATM 4879 O O   . HOH E 3 .   ? -2.65300 18.82200  152.76200 1.000 21.61000 ? 702 HOH A O   1 
HETATM 4880 O O   . HOH E 3 .   ? 37.54500 6.77800   146.89800 1.000 22.27000 ? 703 HOH A O   1 
HETATM 4881 O O   . HOH E 3 .   ? 35.39700 9.61100   167.47100 1.000 18.74000 ? 704 HOH A O   1 
HETATM 4882 O O   . HOH E 3 .   ? 1.14400  25.36500  147.86600 1.000 13.17000 ? 705 HOH A O   1 
HETATM 4883 O O   . HOH E 3 .   ? 20.25800 14.21900  167.67800 1.000 19.19000 ? 706 HOH A O   1 
HETATM 4884 O O   . HOH E 3 .   ? 23.72400 18.52900  165.02100 1.000 10.28000 ? 707 HOH A O   1 
HETATM 4885 O O   . HOH E 3 .   ? 8.84200  27.78400  142.32500 1.000 21.27000 ? 708 HOH A O   1 
HETATM 4886 O O   . HOH E 3 .   ? 25.14700 19.50000  167.07200 1.000 15.50000 ? 709 HOH A O   1 
HETATM 4887 O O   . HOH E 3 .   ? 24.35100 28.24100  165.31400 1.000 26.43000 ? 710 HOH A O   1 
HETATM 4888 O O   . HOH E 3 .   ? 14.53400 32.78500  147.10800 1.000 24.01000 ? 711 HOH A O   1 
HETATM 4889 O O   . HOH E 3 .   ? 27.30900 24.32800  137.25400 1.000 15.51000 ? 712 HOH A O   1 
HETATM 4890 O O   . HOH E 3 .   ? 42.16800 13.69600  142.93600 1.000 32.41000 ? 713 HOH A O   1 
HETATM 4891 O O   . HOH E 3 .   ? 23.23300 19.84700  130.92200 1.000 15.34000 ? 714 HOH A O   1 
HETATM 4892 O O   . HOH E 3 .   ? 1.59900  11.19600  146.95500 1.000 19.43000 ? 715 HOH A O   1 
HETATM 4893 O O   . HOH E 3 .   ? 1.43800  17.43600  162.27400 1.000 34.05000 ? 716 HOH A O   1 
HETATM 4894 O O   . HOH E 3 .   ? 36.79400 3.04800   164.38600 1.000 17.46000 ? 717 HOH A O   1 
HETATM 4895 O O   . HOH E 3 .   ? 17.82000 34.69100  154.69900 1.000 31.72000 ? 718 HOH A O   1 
HETATM 4896 O O   . HOH E 3 .   ? 18.65400 27.96000  168.67600 1.000 32.69000 ? 719 HOH A O   1 
HETATM 4897 O O   . HOH E 3 .   ? 25.25700 -4.26400  118.75700 1.000 42.48000 ? 720 HOH A O   1 
HETATM 4898 O O   . HOH E 3 .   ? 25.41700 14.15800  169.47500 1.000 23.12000 ? 721 HOH A O   1 
HETATM 4899 O O   . HOH E 3 .   ? 33.96500 -6.14300  138.18600 1.000 28.38000 ? 722 HOH A O   1 
HETATM 4900 O O   . HOH E 3 .   ? -0.56200 15.32400  146.38500 1.000 22.68000 ? 723 HOH A O   1 
HETATM 4901 O O   . HOH E 3 .   ? 29.13600 12.07300  172.88800 1.000 25.51000 ? 724 HOH A O   1 
HETATM 4902 O O   . HOH E 3 .   ? -0.33300 23.88700  159.17500 1.000 33.23000 ? 725 HOH A O   1 
HETATM 4903 O O   . HOH E 3 .   ? 14.24200 12.41900  138.88100 1.000 9.78000  ? 726 HOH A O   1 
HETATM 4904 O O   . HOH E 3 .   ? 36.28200 1.70400   151.24300 1.000 13.53000 ? 727 HOH A O   1 
HETATM 4905 O O   . HOH E 3 .   ? 31.12800 -9.78100  148.05600 1.000 30.23000 ? 728 HOH A O   1 
HETATM 4906 O O   . HOH E 3 .   ? 1.23600  11.74800  141.82200 1.000 28.52000 ? 729 HOH A O   1 
HETATM 4907 O O   . HOH E 3 .   ? 34.79500 15.74500  162.63000 1.000 10.70000 ? 730 HOH A O   1 
HETATM 4908 O O   . HOH E 3 .   ? 27.54700 23.70800  139.95800 1.000 12.57000 ? 731 HOH A O   1 
HETATM 4909 O O   . HOH E 3 .   ? 22.24800 -14.45700 141.32100 1.000 16.90000 ? 732 HOH A O   1 
HETATM 4910 O O   . HOH E 3 .   ? 31.04000 17.70800  123.19200 1.000 35.86000 ? 733 HOH A O   1 
HETATM 4911 O O   . HOH E 3 .   ? 34.65300 0.63000   149.16700 1.000 9.23000  ? 734 HOH A O   1 
HETATM 4912 O O   . HOH E 3 .   ? 9.97800  23.79800  141.48500 1.000 24.19000 ? 735 HOH A O   1 
HETATM 4913 O O   . HOH E 3 .   ? 40.52200 24.21700  146.74700 1.000 34.15000 ? 736 HOH A O   1 
HETATM 4914 O O   . HOH E 3 .   ? 27.57100 -9.24500  146.38200 1.000 20.56000 ? 737 HOH A O   1 
HETATM 4915 O O   . HOH E 3 .   ? 27.64600 31.65700  143.23200 1.000 34.85000 ? 738 HOH A O   1 
HETATM 4916 O O   . HOH E 3 .   ? 45.46100 13.40500  148.48600 1.000 35.47000 ? 739 HOH A O   1 
HETATM 4917 O O   . HOH E 3 .   ? 18.71900 21.99300  138.87300 1.000 18.38000 ? 740 HOH A O   1 
HETATM 4918 O O   . HOH E 3 .   ? 4.04500  8.20900   156.55600 1.000 27.53000 ? 741 HOH A O   1 
HETATM 4919 O O   . HOH E 3 .   ? 24.47900 27.67200  162.31300 1.000 11.18000 ? 742 HOH A O   1 
HETATM 4920 O O   . HOH E 3 .   ? 24.64500 34.88000  143.55500 1.000 32.71000 ? 743 HOH A O   1 
HETATM 4921 O O   . HOH E 3 .   ? 25.64000 -6.38400  125.31700 1.000 28.93000 ? 744 HOH A O   1 
HETATM 4922 O O   . HOH E 3 .   ? 34.61800 -2.29400  155.22300 1.000 20.84000 ? 745 HOH A O   1 
HETATM 4923 O O   . HOH E 3 .   ? 37.32600 5.76100   162.02100 1.000 30.28000 ? 746 HOH A O   1 
HETATM 4924 O O   . HOH E 3 .   ? 22.98300 25.14500  137.22400 1.000 32.39000 ? 747 HOH A O   1 
HETATM 4925 O O   . HOH E 3 .   ? 35.15000 24.24400  157.12000 1.000 18.40000 ? 748 HOH A O   1 
HETATM 4926 O O   . HOH E 3 .   ? 34.67900 16.15700  173.84900 1.000 26.98000 ? 749 HOH A O   1 
HETATM 4927 O O   . HOH E 3 .   ? 37.84200 22.35900  158.01400 1.000 24.00000 ? 750 HOH A O   1 
HETATM 4928 O O   . HOH E 3 .   ? 25.40400 24.64300  141.49500 1.000 15.32000 ? 751 HOH A O   1 
HETATM 4929 O O   . HOH E 3 .   ? 2.01500  21.66800  161.09700 1.000 25.06000 ? 752 HOH A O   1 
HETATM 4930 O O   . HOH E 3 .   ? 23.92600 14.73600  126.46000 1.000 16.95000 ? 753 HOH A O   1 
HETATM 4931 O O   . HOH E 3 .   ? 36.89100 15.22200  131.03200 1.000 26.87000 ? 754 HOH A O   1 
HETATM 4932 O O   . HOH E 3 .   ? 30.76900 -9.64800  152.02400 1.000 30.45000 ? 755 HOH A O   1 
HETATM 4933 O O   . HOH E 3 .   ? 36.61500 0.13800   153.57000 1.000 21.82000 ? 756 HOH A O   1 
HETATM 4934 O O   . HOH E 3 .   ? 25.23600 16.18000  122.21700 1.000 26.24000 ? 757 HOH A O   1 
HETATM 4935 O O   . HOH E 3 .   ? 4.22700  19.94500  161.98200 1.000 29.29000 ? 758 HOH A O   1 
HETATM 4936 O O   . HOH E 3 .   ? 24.10800 -13.87500 137.31800 1.000 26.21000 ? 759 HOH A O   1 
HETATM 4937 O O   . HOH E 3 .   ? -0.98300 15.28600  152.68400 1.000 33.73000 ? 760 HOH A O   1 
HETATM 4938 O O   . HOH E 3 .   ? -2.21600 20.46200  154.99500 1.000 20.24000 ? 761 HOH A O   1 
HETATM 4939 O O   . HOH E 3 .   ? 16.25800 29.21800  142.65700 1.000 32.12000 ? 762 HOH A O   1 
HETATM 4940 O O   . HOH E 3 .   ? 14.93400 12.09000  129.38500 1.000 19.57000 ? 763 HOH A O   1 
HETATM 4941 O O   . HOH E 3 .   ? 44.35000 9.23800   155.20200 1.000 29.06000 ? 764 HOH A O   1 
HETATM 4942 O O   . HOH E 3 .   ? 35.63600 -4.32300  156.03200 1.000 38.72000 ? 765 HOH A O   1 
HETATM 4943 O O   . HOH E 3 .   ? 6.80500  17.25600  164.49100 1.000 31.95000 ? 766 HOH A O   1 
HETATM 4944 O O   . HOH E 3 .   ? 39.24900 -1.38700  140.51600 1.000 33.56000 ? 767 HOH A O   1 
HETATM 4945 O O   . HOH E 3 .   ? 7.46800  -3.26300  150.07600 1.000 29.47000 ? 768 HOH A O   1 
HETATM 4946 O O   . HOH E 3 .   ? 30.91300 19.05300  170.45100 1.000 32.25000 ? 769 HOH A O   1 
HETATM 4947 O O   . HOH E 3 .   ? 17.30200 -12.14700 155.85300 1.000 13.41000 ? 770 HOH A O   1 
HETATM 4948 O O   . HOH E 3 .   ? 27.84000 31.05400  154.08700 1.000 21.94000 ? 771 HOH A O   1 
HETATM 4949 O O   . HOH E 3 .   ? 18.11900 -14.09600 151.89400 1.000 33.42000 ? 772 HOH A O   1 
HETATM 4950 O O   . HOH E 3 .   ? 4.45800  5.48200   139.58300 1.000 28.42000 ? 773 HOH A O   1 
HETATM 4951 O O   . HOH E 3 .   ? 4.53100  27.09300  148.43700 1.000 31.11000 ? 774 HOH A O   1 
HETATM 4952 O O   . HOH E 3 .   ? 12.24700 18.04800  136.46400 1.000 36.68000 ? 775 HOH A O   1 
HETATM 4953 O O   . HOH E 3 .   ? 18.10200 -11.96700 150.00300 1.000 27.28000 ? 776 HOH A O   1 
HETATM 4954 O O   . HOH E 3 .   ? 29.185   28.512    163.017   1.000 36.41000 ? 777 HOH A O   1 
HETATM 4955 O O   . HOH E 3 .   ? 39.35200 6.39800   141.50900 1.000 32.70000 ? 778 HOH A O   1 
HETATM 4956 O O   . HOH E 3 .   ? 11.20500 19.70000  137.53400 1.000 36.09000 ? 779 HOH A O   1 
HETATM 4957 O O   . HOH E 3 .   ? 23.82300 -10.11900 148.57900 1.000 16.15000 ? 780 HOH A O   1 
HETATM 4958 O O   . HOH E 3 .   ? 21.06500 22.56300  136.75200 1.000 32.44000 ? 781 HOH A O   1 
HETATM 4959 O O   . HOH E 3 .   ? 24.401   19.641    126.873   1.000 23.53000 ? 782 HOH A O   1 
HETATM 4960 O O   . HOH E 3 .   ? 40.39500 -0.42200  151.59400 1.000 32.73000 ? 783 HOH A O   1 
HETATM 4961 O O   . HOH E 3 .   ? 4.66800  2.84400   151.03500 1.000 33.29000 ? 784 HOH A O   1 
HETATM 4962 O O   . HOH E 3 .   ? 13.15000 -9.24200  135.56600 1.000 31.98000 ? 785 HOH A O   1 
HETATM 4963 O O   . HOH E 3 .   ? 42.43600 11.73400  141.05300 1.000 31.37000 ? 786 HOH A O   1 
HETATM 4964 O O   . HOH E 3 .   ? 19.83100 23.28400  169.87500 1.000 31.28000 ? 787 HOH A O   1 
HETATM 4965 O O   . HOH E 3 .   ? 25.18900 -7.24800  132.25600 1.000 21.77000 ? 788 HOH A O   1 
HETATM 4966 O O   . HOH E 3 .   ? 21.15500 31.72000  159.14300 1.000 33.63000 ? 789 HOH A O   1 
HETATM 4967 O O   . HOH E 3 .   ? 8.33700  10.61700  164.88100 1.000 19.03000 ? 790 HOH A O   1 
HETATM 4968 O O   . HOH E 3 .   ? 16.43600 29.83300  165.07400 1.000 27.62000 ? 791 HOH A O   1 
HETATM 4969 O O   . HOH E 3 .   ? 16.78800 8.60500   177.23400 1.000 24.38000 ? 792 HOH A O   1 
HETATM 4970 O O   . HOH E 3 .   ? 12.91300 8.47400   129.57700 1.000 21.45000 ? 793 HOH A O   1 
HETATM 4971 O O   . HOH E 3 .   ? 10.70700 11.05300  132.47600 1.000 30.52000 ? 794 HOH A O   1 
HETATM 4972 O O   . HOH E 3 .   ? 39.93900 3.65400   135.65600 1.000 32.07000 ? 795 HOH A O   1 
HETATM 4973 O O   . HOH E 3 .   ? 29.13600 12.61300  163.09200 1.000 6.74000  ? 796 HOH A O   1 
HETATM 4974 O O   . HOH E 3 .   ? 8.98000  -6.10900  142.17300 1.000 38.56000 ? 797 HOH A O   1 
HETATM 4975 O O   . HOH E 3 .   ? 38.56600 -2.32400  159.67900 1.000 39.98000 ? 798 HOH A O   1 
HETATM 4976 O O   . HOH E 3 .   ? -1.12500 17.27300  144.86800 1.000 21.82000 ? 799 HOH A O   1 
HETATM 4977 O O   . HOH E 3 .   ? 37.34500 9.42300   145.88500 1.000 29.93000 ? 800 HOH A O   1 
HETATM 4978 O O   . HOH E 3 .   ? 26.80100 -0.53800  131.63700 1.000 34.79000 ? 801 HOH A O   1 
HETATM 4979 O O   . HOH E 3 .   ? 15.30200 -3.49400  132.44200 1.000 29.84000 ? 802 HOH A O   1 
HETATM 4980 O O   . HOH E 3 .   ? 41.05100 19.55000  141.20600 1.000 35.56000 ? 803 HOH A O   1 
HETATM 4981 O O   . HOH E 3 .   ? 41.89300 10.28100  136.25400 1.000 37.05000 ? 804 HOH A O   1 
HETATM 4982 O O   . HOH E 3 .   ? 39.58200 10.39600  134.47600 1.000 24.71000 ? 805 HOH A O   1 
HETATM 4983 O O   . HOH E 3 .   ? 18.82800 -6.62500  127.12200 1.000 34.01000 ? 806 HOH A O   1 
HETATM 4984 O O   . HOH E 3 .   ? 29.622   28.447    158.903   1.000 17.31000 ? 807 HOH A O   1 
HETATM 4985 O O   . HOH E 3 .   ? 22.88200 13.16100  168.63100 1.000 19.82000 ? 808 HOH A O   1 
HETATM 4986 O O   . HOH E 3 .   ? 14.37300 -11.35500 134.03100 1.000 31.72000 ? 809 HOH A O   1 
HETATM 4987 O O   . HOH E 3 .   ? 22.94600 30.33400  158.76800 1.000 19.42000 ? 810 HOH A O   1 
HETATM 4988 O O   . HOH E 3 .   ? 17.81100 12.83300  168.21700 1.000 13.43000 ? 811 HOH A O   1 
HETATM 4989 O O   . HOH E 3 .   ? 40.67000 -2.31400  142.67000 1.000 27.39000 ? 812 HOH A O   1 
HETATM 4990 O O   . HOH E 3 .   ? 4.01600  9.73200   158.79100 1.000 33.85000 ? 813 HOH A O   1 
HETATM 4991 O O   . HOH E 3 .   ? 28.16100 27.59200  156.85300 1.000 11.98000 ? 814 HOH A O   1 
HETATM 4992 O O   . HOH E 3 .   ? 27.41000 24.93300  133.26900 1.000 31.33000 ? 815 HOH A O   1 
HETATM 4993 O O   . HOH E 3 .   ? 39.99500 16.53400  135.90900 1.000 27.79000 ? 816 HOH A O   1 
HETATM 4994 O O   . HOH E 3 .   ? 21.551   13.549    126.868   1.000 19.00000 ? 817 HOH A O   1 
HETATM 4995 O O   . HOH E 3 .   ? 10.33700 8.68700   172.61000 1.000 30.63000 ? 818 HOH A O   1 
HETATM 4996 O O   . HOH E 3 .   ? 39.002   11.956    164.892   1.000 18.04000 ? 819 HOH A O   1 
HETATM 4997 O O   . HOH E 3 .   ? 11.94700 -10.00400 137.36100 1.000 44.54000 ? 820 HOH A O   1 
HETATM 4998 O O   . HOH E 3 .   ? 30.45500 31.05500  142.62700 1.000 32.38000 ? 821 HOH A O   1 
HETATM 4999 O O   . HOH E 3 .   ? 3.94700  15.49200  138.40800 1.000 27.63000 ? 822 HOH A O   1 
HETATM 5000 O O   . HOH E 3 .   ? 22.25100 29.45800  165.69200 1.000 31.79000 ? 823 HOH A O   1 
HETATM 5001 O O   . HOH E 3 .   ? 7.96800  16.33900  137.08700 1.000 33.84000 ? 824 HOH A O   1 
HETATM 5002 O O   . HOH E 3 .   ? 10.33800 13.58700  133.28900 1.000 33.19000 ? 825 HOH A O   1 
HETATM 5003 O O   . HOH E 3 .   ? 28.219   29.309    161.102   1.000 32.78000 ? 826 HOH A O   1 
HETATM 5004 O O   . HOH E 3 .   ? 9.85200  21.39300  139.85300 1.000 30.46000 ? 827 HOH A O   1 
HETATM 5005 O O   . HOH E 3 .   ? 24.56900 36.88200  146.18000 1.000 33.70000 ? 828 HOH A O   1 
HETATM 5006 O O   . HOH E 3 .   ? 33.562   17.030    123.963   1.000 37.11000 ? 829 HOH A O   1 
HETATM 5007 O O   . HOH E 3 .   ? 30.37700 -13.13300 138.22200 1.000 37.84000 ? 830 HOH A O   1 
HETATM 5008 O O   . HOH E 3 .   ? 15.27300 19.34200  132.64300 1.000 19.94000 ? 831 HOH A O   1 
HETATM 5009 O O   . HOH E 3 .   ? 18.96400 11.01200  169.74200 1.000 11.23000 ? 832 HOH A O   1 
HETATM 5010 O O   . HOH E 3 .   ? 5.16600  15.24600  161.33800 1.000 24.48000 ? 833 HOH A O   1 
HETATM 5011 O O   . HOH E 3 .   ? 9.67200  10.79600  171.22700 1.000 34.37000 ? 834 HOH A O   1 
HETATM 5012 O O   . HOH E 3 .   ? 19.81200 30.78100  143.05700 1.000 29.71000 ? 835 HOH A O   1 
HETATM 5013 O O   . HOH E 3 .   ? 16.95400 -9.38400  149.57500 1.000 16.59000 ? 836 HOH A O   1 
HETATM 5014 O O   . HOH E 3 .   ? -3.129   18.102    148.229   1.000 37.43000 ? 837 HOH A O   1 
HETATM 5015 O O   . HOH E 3 .   ? 20.56500 18.67900  132.04900 1.000 18.73000 ? 838 HOH A O   1 
HETATM 5016 O O   . HOH E 3 .   ? 11.15100 14.14300  137.52900 1.000 20.81000 ? 839 HOH A O   1 
HETATM 5017 O O   . HOH E 3 .   ? 8.08700  30.62500  144.24400 1.000 33.39000 ? 840 HOH A O   1 
HETATM 5018 O O   . HOH E 3 .   ? 25.93800 16.67800  168.86100 1.000 34.36000 ? 841 HOH A O   1 
HETATM 5019 O O   . HOH E 3 .   ? 23.37600 37.73100  150.71400 1.000 51.02000 ? 842 HOH A O   1 
HETATM 5020 O O   . HOH E 3 .   ? 38.389   12.203    172.950   1.000 32.78000 ? 843 HOH A O   1 
HETATM 5021 O O   . HOH E 3 .   ? 40.44800 8.37900   162.04500 1.000 29.07000 ? 844 HOH A O   1 
HETATM 5022 O O   . HOH E 3 .   ? 26.17900 33.37200  154.26400 1.000 40.07000 ? 845 HOH A O   1 
HETATM 5023 O O   . HOH E 3 .   ? 21.64800 -14.69800 138.57400 1.000 31.94000 ? 846 HOH A O   1 
HETATM 5024 O O   . HOH E 3 .   ? 5.56100  30.15500  152.75100 1.000 39.14000 ? 847 HOH A O   1 
HETATM 5025 O O   . HOH E 3 .   ? 2.36800  26.68900  150.12500 1.000 30.20000 ? 848 HOH A O   1 
HETATM 5026 O O   . HOH E 3 .   ? 32.408   28.250    139.523   1.000 28.62000 ? 849 HOH A O   1 
HETATM 5027 O O   . HOH E 3 .   ? 6.06700  6.83900   163.16900 1.000 27.24000 ? 850 HOH A O   1 
HETATM 5028 O O   . HOH E 3 .   ? 39.72500 25.19000  144.84200 1.000 34.09000 ? 851 HOH A O   1 
HETATM 5029 O O   . HOH E 3 .   ? 10.98000 -6.84500  146.33100 1.000 42.04000 ? 852 HOH A O   1 
HETATM 5030 O O   . HOH E 3 .   ? 11.23100 29.87000  164.84900 1.000 37.28000 ? 853 HOH A O   1 
HETATM 5031 O O   . HOH E 3 .   ? 6.88300  -2.03800  145.41000 1.000 30.09000 ? 854 HOH A O   1 
HETATM 5032 O O   . HOH E 3 .   ? 35.17500 6.49900   170.19900 1.000 32.87000 ? 855 HOH A O   1 
HETATM 5033 O O   . HOH E 3 .   ? 35.95900 26.92200  143.85900 1.000 20.77000 ? 856 HOH A O   1 
HETATM 5034 O O   . HOH E 3 .   ? 11.12500 10.50900  130.07100 1.000 28.04000 ? 857 HOH A O   1 
HETATM 5035 O O   . HOH E 3 .   ? 26.32300 26.96200  142.44200 1.000 23.43000 ? 858 HOH A O   1 
HETATM 5036 O O   . HOH E 3 .   ? 30.01100 3.85300   132.26600 1.000 32.64000 ? 859 HOH A O   1 
HETATM 5037 O O   . HOH E 3 .   ? 22.92900 20.46700  168.42800 1.000 18.71000 ? 860 HOH A O   1 
HETATM 5038 O O   . HOH E 3 .   ? 9.84500  13.43500  164.54700 1.000 24.72000 ? 861 HOH A O   1 
HETATM 5039 O O   . HOH E 3 .   ? 0.95600  10.34900  154.65400 1.000 33.87000 ? 862 HOH A O   1 
HETATM 5040 O O   . HOH E 3 .   ? 18.80400 30.96600  164.28400 1.000 22.88000 ? 863 HOH A O   1 
HETATM 5041 O O   . HOH E 3 .   ? 16.83700 26.20000  140.33300 1.000 28.39000 ? 864 HOH A O   1 
HETATM 5042 O O   . HOH E 3 .   ? 4.34200  2.88900   160.22200 1.000 34.11000 ? 865 HOH A O   1 
HETATM 5043 O O   . HOH E 3 .   ? 12.15800 28.43100  166.27100 1.000 36.81000 ? 866 HOH A O   1 
HETATM 5044 O O   . HOH E 3 .   ? 22.16300 20.82600  128.86500 1.000 21.38000 ? 867 HOH A O   1 
HETATM 5045 O O   . HOH E 3 .   ? 41.36900 3.61300   138.16900 1.000 38.42000 ? 868 HOH A O   1 
HETATM 5046 O O   . HOH E 3 .   ? 20.32700 -13.18300 149.63400 1.000 31.53000 ? 869 HOH A O   1 
HETATM 5047 O O   . HOH E 3 .   ? 22.37200 27.70100  141.05100 1.000 23.14000 ? 870 HOH A O   1 
HETATM 5048 O O   . HOH E 3 .   ? 37.12300 -0.07300  158.39600 1.000 27.02000 ? 871 HOH A O   1 
HETATM 5049 O O   . HOH E 3 .   ? 36.25400 12.26200  145.98800 1.000 22.96000 ? 872 HOH A O   1 
HETATM 5050 O O   . HOH E 3 .   ? 2.69600  6.48900   153.00000 1.000 31.43000 ? 873 HOH A O   1 
HETATM 5051 O O   . HOH E 3 .   ? 34.99500 16.79100  132.19000 1.000 18.08000 ? 874 HOH A O   1 
HETATM 5052 O O   . HOH E 3 .   ? 42.45400 9.60700   161.84000 1.000 28.35000 ? 875 HOH A O   1 
HETATM 5053 O O   . HOH E 3 .   ? 13.91000 -10.75200 143.61600 1.000 38.29000 ? 876 HOH A O   1 
HETATM 5054 O O   . HOH E 3 .   ? 6.83300  10.30200  167.13700 1.000 29.68000 ? 877 HOH A O   1 
HETATM 5055 O O   . HOH E 3 .   ? 21.38800 30.04600  163.06700 1.000 19.87000 ? 878 HOH A O   1 
HETATM 5056 O O   . HOH E 3 .   ? 9.16000  -5.77600  145.12500 1.000 31.52000 ? 879 HOH A O   1 
HETATM 5057 O O   . HOH E 3 .   ? 4.30500  26.70800  145.29500 1.000 27.74000 ? 880 HOH A O   1 
HETATM 5058 O O   . HOH E 3 .   ? 8.51800  10.16200  160.74400 1.000 25.33000 ? 881 HOH A O   1 
HETATM 5059 O O   . HOH E 3 .   ? 23.107   17.332    125.898   1.000 19.61000 ? 882 HOH A O   1 
HETATM 5060 O O   . HOH E 3 .   ? 12.26500 14.32400  165.06800 1.000 16.48000 ? 883 HOH A O   1 
HETATM 5061 O O   . HOH E 3 .   ? 41.62900 20.98400  143.14700 1.000 29.24000 ? 884 HOH A O   1 
HETATM 5062 O O   . HOH E 3 .   ? 12.65500 -6.82700  134.46500 1.000 28.98000 ? 885 HOH A O   1 
HETATM 5063 O O   . HOH E 3 .   ? 42.51900 7.77700   139.95400 1.000 39.55000 ? 886 HOH A O   1 
HETATM 5064 O O   . HOH E 3 .   ? 40.55500 5.40800   155.33200 1.000 24.52000 ? 887 HOH A O   1 
HETATM 5065 O O   . HOH E 3 .   ? 25.83500 20.60100  124.92100 1.000 33.39000 ? 888 HOH A O   1 
HETATM 5066 O O   . HOH E 3 .   ? 38.99500 5.67000   130.22600 1.000 29.34000 ? 889 HOH A O   1 
HETATM 5067 O O   . HOH E 3 .   ? 17.86700 -13.71600 136.15500 1.000 29.92000 ? 890 HOH A O   1 
HETATM 5068 O O   . HOH E 3 .   ? 26.77700 29.75300  156.49600 1.000 17.24000 ? 891 HOH A O   1 
HETATM 5069 O O   . HOH E 3 .   ? 28.87500 -5.46400  131.43100 1.000 29.47000 ? 892 HOH A O   1 
HETATM 5070 O O   . HOH E 3 .   ? 37.53300 11.39500  167.28100 1.000 24.98000 ? 893 HOH A O   1 
HETATM 5071 O O   . HOH E 3 .   ? 44.76600 10.24700  157.54200 1.000 32.05000 ? 894 HOH A O   1 
HETATM 5072 O O   . HOH E 3 .   ? 20.29000 -16.22500 142.40400 1.000 35.82000 ? 895 HOH A O   1 
HETATM 5073 O O   . HOH E 3 .   ? 7.019    21.024    139.584   1.000 27.11000 ? 896 HOH A O   1 
HETATM 5074 O O   . HOH E 3 .   ? 16.48100 -14.90400 153.78000 1.000 37.29000 ? 897 HOH A O   1 
HETATM 5075 O O   . HOH E 3 .   ? 40.54600 5.89100   134.45000 1.000 29.99000 ? 898 HOH A O   1 
HETATM 5076 O O   . HOH E 3 .   ? 29.27300 -0.10800  132.37300 1.000 35.17000 ? 899 HOH A O   1 
HETATM 5077 O O   . HOH E 3 .   ? 38.15500 -1.64000  152.89900 1.000 34.89000 ? 900 HOH A O   1 
HETATM 5078 O O   . HOH E 3 .   ? 17.02400 29.58800  167.55400 1.000 36.10000 ? 901 HOH A O   1 
HETATM 5079 O O   . HOH E 3 .   ? 6.53000  3.87500   152.70400 1.000 15.25000 ? 902 HOH A O   1 
HETATM 5080 O O   . HOH E 3 .   ? 35.82300 6.91700   167.37200 1.000 25.62000 ? 903 HOH A O   1 
HETATM 5081 O O   . HOH E 3 .   ? 30.04800 -11.06500 146.17800 1.000 35.07000 ? 904 HOH A O   1 
HETATM 5082 O O   . HOH E 3 .   ? 18.74600 17.97400  129.90900 1.000 10.13000 ? 905 HOH A O   1 
HETATM 5083 O O   . HOH E 3 .   ? 29.55000 27.74200  136.32600 1.000 23.58000 ? 906 HOH A O   1 
HETATM 5084 O O   . HOH E 3 .   ? 45.88400 7.81900   151.35900 1.000 33.57000 ? 907 HOH A O   1 
HETATM 5085 O O   . HOH E 3 .   ? 26.58000 20.25500  171.23200 1.000 22.81000 ? 908 HOH A O   1 
HETATM 5086 O O   . HOH E 3 .   ? 25.83300 -8.09800  129.64600 1.000 31.38000 ? 909 HOH A O   1 
HETATM 5087 O O   . HOH E 3 .   ? 20.21900 29.83800  167.46000 1.000 37.11000 ? 910 HOH A O   1 
HETATM 5088 O O   . HOH E 3 .   ? 22.49200 33.71800  155.98000 1.000 30.24000 ? 911 HOH A O   1 
HETATM 5089 O O   . HOH E 3 .   ? 25.14000 -14.15800 148.61800 1.000 33.55000 ? 912 HOH A O   1 
HETATM 5090 O O   . HOH E 3 .   ? 1.20200  12.56100  149.17500 1.000 25.82000 ? 913 HOH A O   1 
HETATM 5091 O O   . HOH E 3 .   ? 30.34000 30.96600  155.15200 1.000 24.94000 ? 914 HOH A O   1 
HETATM 5092 O O   . HOH E 3 .   ? 2.54800  9.64600   136.88400 1.000 48.60000 ? 915 HOH A O   1 
HETATM 5093 O O   . HOH E 3 .   ? 13.19300 37.55600  158.25600 1.000 46.87000 ? 916 HOH A O   1 
HETATM 5094 O O   . HOH E 3 .   ? 14.90900 10.38400  178.02700 1.000 38.51000 ? 917 HOH A O   1 
HETATM 5095 O O   . HOH E 3 .   ? -2.42700 16.54000  142.70200 1.000 24.70000 ? 918 HOH A O   1 
HETATM 5096 O O   . HOH E 3 .   ? 29.66000 28.41100  143.08900 1.000 29.85000 ? 919 HOH A O   1 
HETATM 5097 O O   . HOH E 3 .   ? 17.27000 28.19800  170.87500 1.000 44.01000 ? 920 HOH A O   1 
HETATM 5098 O O   . HOH E 3 .   ? 38.34600 1.41600   155.11600 1.000 27.01000 ? 921 HOH A O   1 
HETATM 5099 O O   . HOH E 3 .   ? 13.50800 14.03700  168.84700 1.000 19.33000 ? 922 HOH A O   1 
HETATM 5100 O O   . HOH E 3 .   ? 30.38800 27.29900  140.92600 1.000 19.21000 ? 923 HOH A O   1 
HETATM 5101 O O   . HOH E 3 .   ? 24.77400 29.97300  160.88000 1.000 28.17000 ? 924 HOH A O   1 
HETATM 5102 O O   . HOH E 3 .   ? 11.39300 13.55700  170.28700 1.000 32.96000 ? 925 HOH A O   1 
HETATM 5103 O O   . HOH E 3 .   ? 36.11400 16.88900  134.71200 1.000 18.60000 ? 926 HOH A O   1 
HETATM 5104 O O   . HOH E 3 .   ? 10.67500 26.57700  167.88300 1.000 37.16000 ? 927 HOH A O   1 
HETATM 5105 O O   . HOH E 3 .   ? 20.64000 15.81600  169.95600 1.000 32.63000 ? 928 HOH A O   1 
HETATM 5106 O O   . HOH E 3 .   ? 40.24000 4.76100   158.01500 1.000 36.60000 ? 929 HOH A O   1 
HETATM 5107 O O   . HOH E 3 .   ? 24.04500 24.00200  170.98700 1.000 31.35000 ? 930 HOH A O   1 
HETATM 5108 O O   . HOH E 3 .   ? 16.55500 16.91600  169.57800 1.000 26.87000 ? 931 HOH A O   1 
HETATM 5109 O O   . HOH E 3 .   ? 18.48300 29.74200  140.62800 1.000 33.87000 ? 932 HOH A O   1 
HETATM 5110 O O   . HOH E 3 .   ? 42.68600 7.32000   135.87900 1.000 36.74000 ? 933 HOH A O   1 
HETATM 5111 O O   . HOH E 3 .   ? 38.17500 2.80000   157.05200 1.000 27.18000 ? 934 HOH A O   1 
HETATM 5112 O O   . HOH E 3 .   ? 19.884   19.526    128.086   1.000 11.99000 ? 935 HOH A O   1 
HETATM 5113 O O   . HOH E 3 .   ? 42.95700 6.07800   137.76200 1.000 36.98000 ? 936 HOH A O   1 
HETATM 5114 O O   . HOH E 3 .   ? 23.96200 21.43100  170.97100 1.000 23.71000 ? 937 HOH A O   1 
HETATM 5115 O O   . HOH E 3 .   ? 15.98500 14.26100  169.90200 1.000 22.74000 ? 938 HOH A O   1 
HETATM 5116 O O   . HOH E 3 .   ? 26.92300 31.77700  158.36700 1.000 36.71000 ? 939 HOH A O   1 
HETATM 5117 O O   . HOH E 3 .   ? 44.27900 8.53000   159.98700 1.000 37.28000 ? 940 HOH A O   1 
HETATM 5118 O O   . HOH E 3 .   ? 43.44000 6.25800   159.07100 1.000 40.26000 ? 941 HOH A O   1 
HETATM 5119 O O   . HOH E 3 .   ? 28.56200 28.62700  139.23000 1.000 33.18000 ? 942 HOH A O   1 
HETATM 5120 O O   . HOH F 3 .   ? 21.68400 11.63300  181.82600 1.000 26.57000 ? 501 HOH B O   1 
HETATM 5121 O O   . HOH F 3 .   ? 6.45000  -0.02000  169.45800 1.000 24.22000 ? 502 HOH B O   1 
HETATM 5122 O O   . HOH F 3 .   ? 9.45000  3.81900   184.09200 1.000 36.96000 ? 503 HOH B O   1 
HETATM 5123 O O   . HOH F 3 .   ? 13.39800 -11.36300 153.43200 1.000 23.30000 ? 504 HOH B O   1 
HETATM 5124 O O   . HOH F 3 .   ? 23.67100 9.49800   193.01300 1.000 30.74000 ? 505 HOH B O   1 
HETATM 5125 O O   . HOH F 3 .   ? 25.88000 -9.87200  198.66900 1.000 35.69000 ? 506 HOH B O   1 
HETATM 5126 O O   . HOH F 3 .   ? 19.78500 -24.65200 192.60400 1.000 20.37000 ? 507 HOH B O   1 
HETATM 5127 O O   . HOH F 3 .   ? -1.85000 -15.36500 160.79700 1.000 30.86000 ? 508 HOH B O   1 
HETATM 5128 O O   . HOH F 3 .   ? -6.26500 -16.90700 182.18800 1.000 33.07000 ? 509 HOH B O   1 
HETATM 5129 O O   . HOH F 3 .   ? 14.50100 8.11900   185.81600 1.000 22.20000 ? 510 HOH B O   1 
HETATM 5130 O O   . HOH F 3 .   ? 4.10200  -23.77500 160.72800 1.000 23.62000 ? 511 HOH B O   1 
HETATM 5131 O O   . HOH F 3 .   ? 26.79200 -7.28300  199.36500 1.000 44.42000 ? 512 HOH B O   1 
HETATM 5132 O O   . HOH F 3 .   ? 21.06200 -28.26300 190.59200 1.000 25.32000 ? 513 HOH B O   1 
HETATM 5133 O O   . HOH F 3 .   ? 37.76000 -11.55200 171.73000 1.000 21.58000 ? 514 HOH B O   1 
HETATM 5134 O O   . HOH F 3 .   ? 30.55400 -11.41100 192.14900 1.000 23.92000 ? 515 HOH B O   1 
HETATM 5135 O O   . HOH F 3 .   ? 17.45100 -29.54100 180.97700 1.000 22.53000 ? 516 HOH B O   1 
HETATM 5136 O O   . HOH F 3 .   ? 28.84400 -12.11500 153.16800 1.000 30.38000 ? 517 HOH B O   1 
HETATM 5137 O O   . HOH F 3 .   ? 40.32800 -16.15400 176.95100 1.000 29.22000 ? 518 HOH B O   1 
HETATM 5138 O O   . HOH F 3 .   ? 19.42900 -25.17000 199.56500 1.000 34.46000 ? 519 HOH B O   1 
HETATM 5139 O O   . HOH F 3 .   ? 5.73300  -25.38900 162.36800 1.000 18.35000 ? 520 HOH B O   1 
HETATM 5140 O O   . HOH F 3 .   ? 1.30900  -5.79000  187.10100 1.000 35.43000 ? 521 HOH B O   1 
HETATM 5141 O O   . HOH F 3 .   ? 16.85300 -21.28200 190.15800 1.000 14.92000 ? 522 HOH B O   1 
HETATM 5142 O O   . HOH F 3 .   ? 22.14700 -23.45200 200.34700 1.000 25.41000 ? 523 HOH B O   1 
HETATM 5143 O O   . HOH F 3 .   ? 28.04500 -9.05900  189.12000 1.000 19.59000 ? 524 HOH B O   1 
HETATM 5144 O O   . HOH F 3 .   ? 17.91700 4.98000   175.08300 1.000 10.02000 ? 525 HOH B O   1 
HETATM 5145 O O   . HOH F 3 .   ? 2.31600  -25.02800 168.77000 1.000 15.89000 ? 526 HOH B O   1 
HETATM 5146 O O   . HOH F 3 .   ? 38.03800 -3.95400  172.92500 1.000 20.39000 ? 527 HOH B O   1 
HETATM 5147 O O   . HOH F 3 .   ? 6.65800  -19.98100 157.63700 1.000 24.82000 ? 528 HOH B O   1 
HETATM 5148 O O   . HOH F 3 .   ? 8.41000  -26.87600 157.49400 1.000 34.48000 ? 529 HOH B O   1 
HETATM 5149 O O   . HOH F 3 .   ? 36.90700 -11.92200 185.19600 1.000 30.47000 ? 530 HOH B O   1 
HETATM 5150 O O   . HOH F 3 .   ? -0.69900 -25.74000 163.70300 1.000 34.09000 ? 531 HOH B O   1 
HETATM 5151 O O   . HOH F 3 .   ? 32.88100 -20.15700 180.06300 1.000 12.27000 ? 532 HOH B O   1 
HETATM 5152 O O   . HOH F 3 .   ? -1.36800 -19.76200 166.40400 1.000 25.18000 ? 533 HOH B O   1 
HETATM 5153 O O   . HOH F 3 .   ? 24.72100 -7.83100  185.57200 1.000 22.91000 ? 534 HOH B O   1 
HETATM 5154 O O   . HOH F 3 .   ? -1.59500 -18.45400 173.15400 1.000 29.18000 ? 535 HOH B O   1 
HETATM 5155 O O   . HOH F 3 .   ? 26.01000 -15.12300 163.13000 1.000 8.78000  ? 536 HOH B O   1 
HETATM 5156 O O   . HOH F 3 .   ? 29.17500 1.04000   192.00000 1.000 26.33000 ? 537 HOH B O   1 
HETATM 5157 O O   . HOH F 3 .   ? 17.67600 -22.25700 183.13800 1.000 8.87000  ? 538 HOH B O   1 
HETATM 5158 O O   . HOH F 3 .   ? 1.30100  -11.79200 185.83600 1.000 27.60000 ? 539 HOH B O   1 
HETATM 5159 O O   . HOH F 3 .   ? 33.87100 -14.01400 193.11000 1.000 30.52000 ? 540 HOH B O   1 
HETATM 5160 O O   . HOH F 3 .   ? 27.31200 -0.61000  192.85300 1.000 21.67000 ? 541 HOH B O   1 
HETATM 5161 O O   . HOH F 3 .   ? 18.67300 -6.34300  153.16100 1.000 10.26000 ? 542 HOH B O   1 
HETATM 5162 O O   . HOH F 3 .   ? -3.87500 -17.28700 173.35400 1.000 34.78000 ? 543 HOH B O   1 
HETATM 5163 O O   . HOH F 3 .   ? 27.46100 -21.38200 167.04800 1.000 13.08000 ? 544 HOH B O   1 
HETATM 5164 O O   . HOH F 3 .   ? 9.42200  2.40200   186.28000 1.000 21.63000 ? 545 HOH B O   1 
HETATM 5165 O O   . HOH F 3 .   ? 11.39200 5.19100   181.00100 1.000 19.50000 ? 546 HOH B O   1 
HETATM 5166 O O   . HOH F 3 .   ? 21.988   -12.478   198.870   1.000 25.01000 ? 547 HOH B O   1 
HETATM 5167 O O   . HOH F 3 .   ? 34.62000 4.29400   185.88300 1.000 26.65000 ? 548 HOH B O   1 
HETATM 5168 O O   . HOH F 3 .   ? 12.01400 -19.53100 191.54000 1.000 26.53000 ? 549 HOH B O   1 
HETATM 5169 O O   . HOH F 3 .   ? 23.40900 -29.58700 167.91400 1.000 14.93000 ? 550 HOH B O   1 
HETATM 5170 O O   . HOH F 3 .   ? 31.59500 -3.59100  186.97600 1.000 11.69000 ? 551 HOH B O   1 
HETATM 5171 O O   . HOH F 3 .   ? 6.34100  3.51900   179.32100 1.000 34.65000 ? 552 HOH B O   1 
HETATM 5172 O O   . HOH F 3 .   ? 22.32700 -29.05000 165.10500 1.000 18.40000 ? 553 HOH B O   1 
HETATM 5173 O O   . HOH F 3 .   ? 21.78300 -26.88600 194.40600 1.000 31.24000 ? 554 HOH B O   1 
HETATM 5174 O O   . HOH F 3 .   ? 27.53500 -30.76600 179.28200 1.000 14.66000 ? 555 HOH B O   1 
HETATM 5175 O O   . HOH F 3 .   ? 19.04000 -16.55300 166.55400 1.000 6.03000  ? 556 HOH B O   1 
HETATM 5176 O O   . HOH F 3 .   ? 27.24200 3.78200   197.88800 1.000 24.89000 ? 557 HOH B O   1 
HETATM 5177 O O   . HOH F 3 .   ? 11.95400 -36.34500 177.60600 1.000 30.36000 ? 558 HOH B O   1 
HETATM 5178 O O   . HOH F 3 .   ? 2.63700  -13.33100 186.77400 1.000 23.75000 ? 559 HOH B O   1 
HETATM 5179 O O   . HOH F 3 .   ? 13.32400 -8.40800  159.03300 1.000 11.57000 ? 560 HOH B O   1 
HETATM 5180 O O   . HOH F 3 .   ? -0.99600 -5.96700  167.60600 1.000 35.01000 ? 561 HOH B O   1 
HETATM 5181 O O   . HOH F 3 .   ? -0.39900 -19.00300 185.44600 1.000 23.57000 ? 562 HOH B O   1 
HETATM 5182 O O   . HOH F 3 .   ? 10.86300 -16.19300 182.33500 1.000 14.77000 ? 563 HOH B O   1 
HETATM 5183 O O   . HOH F 3 .   ? 20.39000 -9.57400  184.88700 1.000 16.12000 ? 564 HOH B O   1 
HETATM 5184 O O   . HOH F 3 .   ? 17.57600 4.98800   190.82900 1.000 16.95000 ? 565 HOH B O   1 
HETATM 5185 O O   . HOH F 3 .   ? 6.57100  -0.22800  155.58000 1.000 31.23000 ? 566 HOH B O   1 
HETATM 5186 O O   . HOH F 3 .   ? 4.06200  -6.05100  167.46300 1.000 19.25000 ? 567 HOH B O   1 
HETATM 5187 O O   . HOH F 3 .   ? 34.60000 -14.07200 177.81800 1.000 20.89000 ? 568 HOH B O   1 
HETATM 5188 O O   . HOH F 3 .   ? 6.05900  3.58300   181.56700 1.000 37.44000 ? 569 HOH B O   1 
HETATM 5189 O O   . HOH F 3 .   ? 22.12700 10.16300  190.80700 1.000 18.44000 ? 570 HOH B O   1 
HETATM 5190 O O   . HOH F 3 .   ? 6.44100  0.64900   166.78300 1.000 29.32000 ? 571 HOH B O   1 
HETATM 5191 O O   . HOH F 3 .   ? 5.56900  0.05000   188.58000 1.000 28.00000 ? 572 HOH B O   1 
HETATM 5192 O O   . HOH F 3 .   ? 40.72400 -6.35500  179.25500 1.000 22.65000 ? 573 HOH B O   1 
HETATM 5193 O O   . HOH F 3 .   ? 14.40200 -27.64600 182.40000 1.000 15.33000 ? 574 HOH B O   1 
HETATM 5194 O O   . HOH F 3 .   ? 12.32600 -9.53400  184.86200 1.000 12.75000 ? 575 HOH B O   1 
HETATM 5195 O O   . HOH F 3 .   ? 12.31100 -32.06400 171.39000 1.000 18.87000 ? 576 HOH B O   1 
HETATM 5196 O O   . HOH F 3 .   ? 38.01000 -22.38100 166.13800 1.000 31.68000 ? 577 HOH B O   1 
HETATM 5197 O O   . HOH F 3 .   ? -0.64000 -6.67100  174.58600 1.000 21.17000 ? 578 HOH B O   1 
HETATM 5198 O O   . HOH F 3 .   ? 30.71900 11.80600  182.67800 1.000 31.88000 ? 579 HOH B O   1 
HETATM 5199 O O   . HOH F 3 .   ? 21.94700 -28.18600 185.41300 1.000 13.24000 ? 580 HOH B O   1 
HETATM 5200 O O   . HOH F 3 .   ? 25.01300 -18.75600 160.53300 1.000 8.90000  ? 581 HOH B O   1 
HETATM 5201 O O   . HOH F 3 .   ? 23.22000 -27.37700 163.02100 1.000 16.14000 ? 582 HOH B O   1 
HETATM 5202 O O   . HOH F 3 .   ? 26.02400 -21.18300 202.09300 1.000 30.19000 ? 583 HOH B O   1 
HETATM 5203 O O   . HOH F 3 .   ? 25.17200 -16.90900 201.14600 1.000 32.63000 ? 584 HOH B O   1 
HETATM 5204 O O   . HOH F 3 .   ? 21.77500 -7.62400  154.12900 1.000 9.01000  ? 585 HOH B O   1 
HETATM 5205 O O   . HOH F 3 .   ? 19.46900 -8.94600  182.53900 1.000 16.33000 ? 586 HOH B O   1 
HETATM 5206 O O   . HOH F 3 .   ? 7.93400  0.70300   171.57400 1.000 10.73000 ? 587 HOH B O   1 
HETATM 5207 O O   . HOH F 3 .   ? 27.77100 -20.82300 174.99100 1.000 9.35000  ? 588 HOH B O   1 
HETATM 5208 O O   . HOH F 3 .   ? 34.10600 -27.99800 172.34400 1.000 17.15000 ? 589 HOH B O   1 
HETATM 5209 O O   . HOH F 3 .   ? 14.37000 -18.50100 191.37900 1.000 25.19000 ? 590 HOH B O   1 
HETATM 5210 O O   . HOH F 3 .   ? 39.42800 -16.29300 173.00800 1.000 20.50000 ? 591 HOH B O   1 
HETATM 5211 O O   . HOH F 3 .   ? -2.63200 -21.86800 177.37900 1.000 23.35000 ? 592 HOH B O   1 
HETATM 5212 O O   . HOH F 3 .   ? -3.41100 -27.79100 170.41400 1.000 33.36000 ? 593 HOH B O   1 
HETATM 5213 O O   . HOH F 3 .   ? 14.31000 -4.49400  157.90600 1.000 17.84000 ? 594 HOH B O   1 
HETATM 5214 O O   . HOH F 3 .   ? 31.91100 -11.38500 159.17100 1.000 11.98000 ? 595 HOH B O   1 
HETATM 5215 O O   . HOH F 3 .   ? 31.80400 -8.85400  192.53000 1.000 24.76000 ? 596 HOH B O   1 
HETATM 5216 O O   . HOH F 3 .   ? 16.99700 -29.37700 158.71500 1.000 32.29000 ? 597 HOH B O   1 
HETATM 5217 O O   . HOH F 3 .   ? 32.03300 -10.27200 199.99900 1.000 38.26000 ? 598 HOH B O   1 
HETATM 5218 O O   . HOH F 3 .   ? 25.54600 -21.35100 160.83500 1.000 10.69000 ? 599 HOH B O   1 
HETATM 5219 O O   . HOH F 3 .   ? 22.60900 -16.43500 164.70700 1.000 8.61000  ? 600 HOH B O   1 
HETATM 5220 O O   . HOH F 3 .   ? 4.31000  -3.57400  185.29800 1.000 22.62000 ? 601 HOH B O   1 
HETATM 5221 O O   . HOH F 3 .   ? -2.99800 -22.68700 165.89600 1.000 32.15000 ? 602 HOH B O   1 
HETATM 5222 O O   . HOH F 3 .   ? 27.68200 -3.00000  183.39800 1.000 8.61000  ? 603 HOH B O   1 
HETATM 5223 O O   . HOH F 3 .   ? 2.65800  -14.95600 160.51400 1.000 25.82000 ? 604 HOH B O   1 
HETATM 5224 O O   . HOH F 3 .   ? 7.71800  -24.92300 183.35500 1.000 13.31000 ? 605 HOH B O   1 
HETATM 5225 O O   . HOH F 3 .   ? 21.59200 -30.12100 177.27100 1.000 13.00000 ? 606 HOH B O   1 
HETATM 5226 O O   . HOH F 3 .   ? 9.61000  -13.37100 189.50000 1.000 23.12000 ? 607 HOH B O   1 
HETATM 5227 O O   . HOH F 3 .   ? 11.84700 -10.93000 159.31800 1.000 10.99000 ? 608 HOH B O   1 
HETATM 5228 O O   . HOH F 3 .   ? 22.19900 -18.22600 182.81000 1.000 7.46000  ? 609 HOH B O   1 
HETATM 5229 O O   . HOH F 3 .   ? 28.59000 5.91000   179.03700 1.000 11.09000 ? 610 HOH B O   1 
HETATM 5230 O O   . HOH F 3 .   ? 20.73300 8.93200   178.64200 1.000 18.59000 ? 611 HOH B O   1 
HETATM 5231 O O   . HOH F 3 .   ? 36.05300 3.37300   183.65900 1.000 32.64000 ? 612 HOH B O   1 
HETATM 5232 O O   . HOH F 3 .   ? 33.52100 -16.18100 161.64300 1.000 27.82000 ? 613 HOH B O   1 
HETATM 5233 O O   . HOH F 3 .   ? 23.90400 -15.76100 152.33400 1.000 25.08000 ? 614 HOH B O   1 
HETATM 5234 O O   . HOH F 3 .   ? 0.68500  -26.91000 180.34100 1.000 24.93000 ? 615 HOH B O   1 
HETATM 5235 O O   . HOH F 3 .   ? 17.43500 -8.30200  157.41000 1.000 16.06000 ? 616 HOH B O   1 
HETATM 5236 O O   . HOH F 3 .   ? 27.65500 -7.04700  174.81600 1.000 6.98000  ? 617 HOH B O   1 
HETATM 5237 O O   . HOH F 3 .   ? 4.43400  -4.59700  156.76700 1.000 34.81000 ? 618 HOH B O   1 
HETATM 5238 O O   . HOH F 3 .   ? 21.39700 5.89300   196.03300 1.000 21.07000 ? 619 HOH B O   1 
HETATM 5239 O O   . HOH F 3 .   ? 10.27500 -3.76000  192.25600 1.000 21.35000 ? 620 HOH B O   1 
HETATM 5240 O O   . HOH F 3 .   ? 34.78700 -6.52700  162.22600 1.000 15.65000 ? 621 HOH B O   1 
HETATM 5241 O O   . HOH F 3 .   ? 27.61300 -19.97600 194.14300 1.000 14.19000 ? 622 HOH B O   1 
HETATM 5242 O O   . HOH F 3 .   ? 25.01600 -25.50800 180.61900 1.000 9.88000  ? 623 HOH B O   1 
HETATM 5243 O O   . HOH F 3 .   ? 9.31400  -7.66100  189.23000 1.000 17.86000 ? 624 HOH B O   1 
HETATM 5244 O O   . HOH F 3 .   ? 8.63300  -1.57800  153.47600 1.000 21.77000 ? 625 HOH B O   1 
HETATM 5245 O O   . HOH F 3 .   ? 26.63600 -4.68900  176.25500 1.000 9.15000  ? 626 HOH B O   1 
HETATM 5246 O O   . HOH F 3 .   ? 30.40600 6.33000   185.38200 1.000 20.45000 ? 627 HOH B O   1 
HETATM 5247 O O   . HOH F 3 .   ? 20.17900 -29.75000 170.74600 1.000 13.02000 ? 628 HOH B O   1 
HETATM 5248 O O   . HOH F 3 .   ? 13.95300 -36.21400 176.33100 1.000 32.55000 ? 629 HOH B O   1 
HETATM 5249 O O   . HOH F 3 .   ? 14.91200 -15.21000 196.37800 1.000 8.36000  ? 630 HOH B O   1 
HETATM 5250 O O   . HOH F 3 .   ? 18.93700 -19.04000 161.72300 1.000 10.93000 ? 631 HOH B O   1 
HETATM 5251 O O   . HOH F 3 .   ? -1.77200 -22.69400 174.33800 1.000 31.50000 ? 632 HOH B O   1 
HETATM 5252 O O   . HOH F 3 .   ? 2.15100  -8.38000  188.94400 1.000 30.46000 ? 633 HOH B O   1 
HETATM 5253 O O   . HOH F 3 .   ? 9.35000  -14.04600 193.72000 1.000 28.93000 ? 634 HOH B O   1 
HETATM 5254 O O   . HOH F 3 .   ? 33.95200 -8.19700  164.47300 1.000 10.96000 ? 635 HOH B O   1 
HETATM 5255 O O   . HOH F 3 .   ? 4.19900  -1.90500  171.96100 1.000 16.73000 ? 636 HOH B O   1 
HETATM 5256 O O   . HOH F 3 .   ? 2.16400  -29.35900 163.93500 1.000 33.18000 ? 637 HOH B O   1 
HETATM 5257 O O   . HOH F 3 .   ? 8.41500  0.29600   164.96700 1.000 12.50000 ? 638 HOH B O   1 
HETATM 5258 O O   . HOH F 3 .   ? 6.05900  -8.52400  157.45300 1.000 26.82000 ? 639 HOH B O   1 
HETATM 5259 O O   . HOH F 3 .   ? 35.20400 -14.94900 191.19400 1.000 21.52000 ? 640 HOH B O   1 
HETATM 5260 O O   . HOH F 3 .   ? 5.75000  -5.46700  163.07800 1.000 11.13000 ? 641 HOH B O   1 
HETATM 5261 O O   . HOH F 3 .   ? 13.64800 -30.59100 169.59300 1.000 12.67000 ? 642 HOH B O   1 
HETATM 5262 O O   . HOH F 3 .   ? 14.62800 -18.37700 179.52700 1.000 5.48000  ? 643 HOH B O   1 
HETATM 5263 O O   . HOH F 3 .   ? -2.52200 -8.02700  172.99400 1.000 24.59000 ? 644 HOH B O   1 
HETATM 5264 O O   . HOH F 3 .   ? 37.49300 -17.29300 171.34400 1.000 16.51000 ? 645 HOH B O   1 
HETATM 5265 O O   . HOH F 3 .   ? 31.05700 -26.54900 167.21500 1.000 23.51000 ? 646 HOH B O   1 
HETATM 5266 O O   . HOH F 3 .   ? 17.67400 -31.93500 177.98200 1.000 15.61000 ? 647 HOH B O   1 
HETATM 5267 O O   . HOH F 3 .   ? 40.98600 -2.73100  184.79600 1.000 39.59000 ? 648 HOH B O   1 
HETATM 5268 O O   . HOH F 3 .   ? 9.39100  -6.11000  194.52900 1.000 26.80000 ? 649 HOH B O   1 
HETATM 5269 O O   . HOH F 3 .   ? 17.52500 -21.12900 194.68700 1.000 15.20000 ? 650 HOH B O   1 
HETATM 5270 O O   . HOH F 3 .   ? 30.02300 -18.99500 176.20300 1.000 14.60000 ? 651 HOH B O   1 
HETATM 5271 O O   . HOH F 3 .   ? 18.40500 -17.97700 189.62200 1.000 7.94000  ? 652 HOH B O   1 
HETATM 5272 O O   . HOH F 3 .   ? 24.025   -8.740    204.405   1.000 22.04000 ? 653 HOH B O   1 
HETATM 5273 O O   . HOH F 3 .   ? 30.66400 -31.18400 172.16800 1.000 28.60000 ? 654 HOH B O   1 
HETATM 5274 O O   . HOH F 3 .   ? 37.04300 -6.96400  159.15300 1.000 33.48000 ? 655 HOH B O   1 
HETATM 5275 O O   . HOH F 3 .   ? 35.58200 -5.25600  167.35000 1.000 27.64000 ? 656 HOH B O   1 
HETATM 5276 O O   . HOH F 3 .   ? 7.16200  -5.63100  183.62200 1.000 12.59000 ? 657 HOH B O   1 
HETATM 5277 O O   . HOH F 3 .   ? 35.98700 -15.05100 170.73100 1.000 12.40000 ? 658 HOH B O   1 
HETATM 5278 O O   . HOH F 3 .   ? -3.33500 -8.95500  177.89600 1.000 26.02000 ? 659 HOH B O   1 
HETATM 5279 O O   . HOH F 3 .   ? 13.67800 -8.70900  196.43200 1.000 16.52000 ? 660 HOH B O   1 
HETATM 5280 O O   . HOH F 3 .   ? 32.70100 -21.19700 189.37400 1.000 12.55000 ? 661 HOH B O   1 
HETATM 5281 O O   . HOH F 3 .   ? 12.65800 -30.85000 183.52100 1.000 28.32000 ? 662 HOH B O   1 
HETATM 5282 O O   . HOH F 3 .   ? 19.54100 -17.79200 159.22700 1.000 14.88000 ? 663 HOH B O   1 
HETATM 5283 O O   . HOH F 3 .   ? -4.26800 -8.91000  180.35400 1.000 28.64000 ? 664 HOH B O   1 
HETATM 5284 O O   . HOH F 3 .   ? 7.59800  -23.20400 186.35100 1.000 38.94000 ? 665 HOH B O   1 
HETATM 5285 O O   . HOH F 3 .   ? 20.83900 -9.88700  158.89900 1.000 11.45000 ? 666 HOH B O   1 
HETATM 5286 O O   . HOH F 3 .   ? 15.11000 -22.64100 161.15900 1.000 10.96000 ? 667 HOH B O   1 
HETATM 5287 O O   . HOH F 3 .   ? 35.18800 -15.68700 196.37600 1.000 30.71000 ? 668 HOH B O   1 
HETATM 5288 O O   . HOH F 3 .   ? 33.84000 -26.38000 185.90800 1.000 11.19000 ? 669 HOH B O   1 
HETATM 5289 O O   . HOH F 3 .   ? 28.17300 -17.63400 202.00400 1.000 33.51000 ? 670 HOH B O   1 
HETATM 5290 O O   . HOH F 3 .   ? 11.64600 -27.93500 163.87800 1.000 14.72000 ? 671 HOH B O   1 
HETATM 5291 O O   . HOH F 3 .   ? 13.41100 -17.15600 181.79600 1.000 8.00000  ? 672 HOH B O   1 
HETATM 5292 O O   . HOH F 3 .   ? 32.41500 -3.68100  191.85900 1.000 22.11000 ? 673 HOH B O   1 
HETATM 5293 O O   . HOH F 3 .   ? 5.60900  -9.19300  189.54700 1.000 27.13000 ? 674 HOH B O   1 
HETATM 5294 O O   . HOH F 3 .   ? 1.49200  -8.86400  166.83600 1.000 22.04000 ? 675 HOH B O   1 
HETATM 5295 O O   . HOH F 3 .   ? 24.80700 11.19000  186.63400 1.000 26.78000 ? 676 HOH B O   1 
HETATM 5296 O O   . HOH F 3 .   ? 12.81400 -23.35100 157.97200 1.000 14.84000 ? 677 HOH B O   1 
HETATM 5297 O O   . HOH F 3 .   ? 14.86300 -8.79500  156.85100 1.000 14.46000 ? 678 HOH B O   1 
HETATM 5298 O O   . HOH F 3 .   ? 10.35700 -9.78800  189.01300 1.000 20.76000 ? 679 HOH B O   1 
HETATM 5299 O O   . HOH F 3 .   ? 9.68800  -5.18000  153.46100 1.000 16.66000 ? 680 HOH B O   1 
HETATM 5300 O O   . HOH F 3 .   ? 23.19300 -25.18000 196.65800 1.000 17.66000 ? 681 HOH B O   1 
HETATM 5301 O O   . HOH F 3 .   ? 24.97900 -5.35800  196.30300 1.000 29.79000 ? 682 HOH B O   1 
HETATM 5302 O O   . HOH F 3 .   ? 8.65600  5.05200   178.22700 1.000 32.05000 ? 683 HOH B O   1 
HETATM 5303 O O   . HOH F 3 .   ? 1.01200  -4.43900  172.12500 1.000 24.63000 ? 684 HOH B O   1 
HETATM 5304 O O   . HOH F 3 .   ? 19.57100 -16.61900 155.98800 1.000 23.33000 ? 685 HOH B O   1 
HETATM 5305 O O   . HOH F 3 .   ? 39.15900 -23.55300 175.34800 1.000 18.93000 ? 686 HOH B O   1 
HETATM 5306 O O   . HOH F 3 .   ? 24.98400 -22.17300 158.15500 1.000 16.31000 ? 687 HOH B O   1 
HETATM 5307 O O   . HOH F 3 .   ? 17.07200 -16.96000 158.91200 1.000 26.00000 ? 688 HOH B O   1 
HETATM 5308 O O   . HOH F 3 .   ? 7.01800  -15.17900 160.74000 1.000 16.36000 ? 689 HOH B O   1 
HETATM 5309 O O   . HOH F 3 .   ? 32.89300 -20.64800 161.02600 1.000 32.53000 ? 690 HOH B O   1 
HETATM 5310 O O   . HOH F 3 .   ? 7.14100  -16.02200 188.98200 1.000 34.95000 ? 691 HOH B O   1 
HETATM 5311 O O   . HOH F 3 .   ? 34.32500 -10.14700 160.30100 1.000 19.38000 ? 692 HOH B O   1 
HETATM 5312 O O   . HOH F 3 .   ? 5.26600  -2.30700  182.80000 1.000 21.92000 ? 693 HOH B O   1 
HETATM 5313 O O   . HOH F 3 .   ? 27.92000 -6.48800  191.72400 1.000 31.33000 ? 694 HOH B O   1 
HETATM 5314 O O   . HOH F 3 .   ? 32.25400 -18.59400 201.02500 1.000 20.30000 ? 695 HOH B O   1 
HETATM 5315 O O   . HOH F 3 .   ? 26.18100 -29.07600 168.34700 1.000 20.31000 ? 696 HOH B O   1 
HETATM 5316 O O   . HOH F 3 .   ? 14.62400 -15.00000 158.05200 1.000 23.04000 ? 697 HOH B O   1 
HETATM 5317 O O   . HOH F 3 .   ? 0.83400  -23.34900 184.37100 1.000 25.83000 ? 698 HOH B O   1 
HETATM 5318 O O   . HOH F 3 .   ? 16.60000 -31.94300 180.54500 1.000 26.25000 ? 699 HOH B O   1 
HETATM 5319 O O   . HOH F 3 .   ? 22.64600 8.39100   168.58600 1.000 11.90000 ? 700 HOH B O   1 
HETATM 5320 O O   . HOH F 3 .   ? 20.68300 5.77300   174.91100 1.000 8.11000  ? 701 HOH B O   1 
HETATM 5321 O O   . HOH F 3 .   ? 20.55800 -21.66700 202.51200 1.000 33.97000 ? 702 HOH B O   1 
HETATM 5322 O O   . HOH F 3 .   ? 28.38600 -21.43100 162.23600 1.000 18.40000 ? 703 HOH B O   1 
HETATM 5323 O O   . HOH F 3 .   ? 1.80500  -32.06700 167.75500 1.000 32.17000 ? 704 HOH B O   1 
HETATM 5324 O O   . HOH F 3 .   ? 22.48200 -20.87400 154.21900 1.000 19.86000 ? 705 HOH B O   1 
HETATM 5325 O O   . HOH F 3 .   ? 4.69200  -22.88000 168.17800 1.000 26.32000 ? 706 HOH B O   1 
HETATM 5326 O O   . HOH F 3 .   ? 27.03400 -32.94700 183.56100 1.000 25.88000 ? 707 HOH B O   1 
HETATM 5327 O O   . HOH F 3 .   ? 2.01300  -0.21200  178.19500 1.000 38.90000 ? 708 HOH B O   1 
HETATM 5328 O O   . HOH F 3 .   ? 36.02700 -0.37000  186.59600 1.000 28.78000 ? 709 HOH B O   1 
HETATM 5329 O O   . HOH F 3 .   ? -5.86600 -14.13600 167.69600 1.000 41.08000 ? 710 HOH B O   1 
HETATM 5330 O O   . HOH F 3 .   ? 33.62800 -7.15300  193.33800 1.000 31.70000 ? 711 HOH B O   1 
HETATM 5331 O O   . HOH F 3 .   ? 11.21400 4.79300   174.29200 1.000 18.38000 ? 712 HOH B O   1 
HETATM 5332 O O   . HOH F 3 .   ? 28.12800 -31.58500 171.85700 1.000 21.02000 ? 713 HOH B O   1 
HETATM 5333 O O   . HOH F 3 .   ? 4.57500  1.62400   180.76000 1.000 35.06000 ? 714 HOH B O   1 
HETATM 5334 O O   . HOH F 3 .   ? 32.78800 -26.56800 183.20100 1.000 13.42000 ? 715 HOH B O   1 
HETATM 5335 O O   . HOH F 3 .   ? 16.60200 -20.30700 160.59100 1.000 12.73000 ? 716 HOH B O   1 
HETATM 5336 O O   . HOH F 3 .   ? 31.27000 8.54500   178.35300 1.000 19.50000 ? 717 HOH B O   1 
HETATM 5337 O O   . HOH F 3 .   ? 20.02400 -16.40600 198.91700 1.000 15.20000 ? 718 HOH B O   1 
HETATM 5338 O O   . HOH F 3 .   ? 35.41300 -26.78300 177.19300 1.000 23.04000 ? 719 HOH B O   1 
HETATM 5339 O O   . HOH F 3 .   ? 30.83200 -15.75500 157.60200 1.000 22.21000 ? 720 HOH B O   1 
HETATM 5340 O O   . HOH F 3 .   ? -4.52000 -8.06400  169.73700 1.000 36.33000 ? 721 HOH B O   1 
HETATM 5341 O O   . HOH F 3 .   ? 13.78000 -29.59800 160.43300 1.000 30.07000 ? 722 HOH B O   1 
HETATM 5342 O O   . HOH F 3 .   ? 33.91600 -16.51100 201.37000 1.000 25.46000 ? 723 HOH B O   1 
HETATM 5343 O O   . HOH F 3 .   ? -3.45100 -22.00300 162.07400 1.000 36.11000 ? 724 HOH B O   1 
HETATM 5344 O O   . HOH F 3 .   ? 14.24500 -28.98000 163.55700 1.000 14.16000 ? 725 HOH B O   1 
HETATM 5345 O O   . HOH F 3 .   ? 29.41300 -17.75900 181.02800 1.000 20.27000 ? 726 HOH B O   1 
HETATM 5346 O O   . HOH F 3 .   ? 11.08300 -11.06800 187.02000 1.000 10.23000 ? 727 HOH B O   1 
HETATM 5347 O O   . HOH F 3 .   ? 31.57100 -14.03800 192.55900 1.000 23.23000 ? 728 HOH B O   1 
HETATM 5348 O O   . HOH F 3 .   ? 33.98400 -12.92200 162.84600 1.000 29.36000 ? 729 HOH B O   1 
HETATM 5349 O O   . HOH F 3 .   ? 34.93900 -8.83100  173.43400 1.000 14.67000 ? 730 HOH B O   1 
HETATM 5350 O O   . HOH F 3 .   ? 33.90900 -7.31200  175.66300 1.000 11.73000 ? 731 HOH B O   1 
HETATM 5351 O O   . HOH F 3 .   ? 21.82500 10.91300  169.54900 1.000 12.72000 ? 732 HOH B O   1 
HETATM 5352 O O   . HOH F 3 .   ? 15.92100 6.13100   177.95700 1.000 23.96000 ? 733 HOH B O   1 
HETATM 5353 O O   . HOH F 3 .   ? 7.19900  -27.58900 183.41500 1.000 26.08000 ? 734 HOH B O   1 
HETATM 5354 O O   . HOH F 3 .   ? 36.13700 -0.00300  173.36500 1.000 28.73000 ? 735 HOH B O   1 
HETATM 5355 O O   . HOH F 3 .   ? 12.90300 -27.53500 157.40600 1.000 32.38000 ? 736 HOH B O   1 
HETATM 5356 O O   . HOH F 3 .   ? 9.15100  -10.83100 159.19900 1.000 14.63000 ? 737 HOH B O   1 
HETATM 5357 O O   . HOH F 3 .   ? 34.59500 -4.68900  169.46600 1.000 21.22000 ? 738 HOH B O   1 
HETATM 5358 O O   . HOH F 3 .   ? 36.37100 -18.91100 162.89100 1.000 32.26000 ? 739 HOH B O   1 
HETATM 5359 O O   . HOH F 3 .   ? 13.18600 -35.76500 182.41800 1.000 33.00000 ? 740 HOH B O   1 
HETATM 5360 O O   . HOH F 3 .   ? -1.64500 -13.08200 184.86700 1.000 29.83000 ? 741 HOH B O   1 
HETATM 5361 O O   . HOH F 3 .   ? 19.44000 -26.84100 188.27300 1.000 18.75000 ? 742 HOH B O   1 
HETATM 5362 O O   . HOH F 3 .   ? 39.07500 -9.34800  173.88900 1.000 35.59000 ? 743 HOH B O   1 
HETATM 5363 O O   . HOH F 3 .   ? 28.24600 -10.87400 193.52700 1.000 30.42000 ? 744 HOH B O   1 
HETATM 5364 O O   . HOH F 3 .   ? 27.84000 11.28100  183.81900 1.000 18.31000 ? 745 HOH B O   1 
HETATM 5365 O O   . HOH F 3 .   ? 32.50200 -15.49400 181.66100 1.000 31.77000 ? 746 HOH B O   1 
HETATM 5366 O O   . HOH F 3 .   ? 12.07900 -21.61200 187.07500 1.000 17.47000 ? 747 HOH B O   1 
HETATM 5367 O O   . HOH F 3 .   ? -2.51700 -27.16400 174.19100 1.000 34.64000 ? 748 HOH B O   1 
HETATM 5368 O O   . HOH F 3 .   ? 30.81400 4.56200   178.57900 1.000 19.18000 ? 749 HOH B O   1 
HETATM 5369 O O   . HOH F 3 .   ? 1.83400  -3.85800  169.80700 1.000 28.37000 ? 750 HOH B O   1 
HETATM 5370 O O   . HOH F 3 .   ? -0.62600 -5.80200  179.73600 1.000 33.38000 ? 751 HOH B O   1 
HETATM 5371 O O   . HOH F 3 .   ? 11.41800 -5.76800  150.72900 1.000 25.14000 ? 752 HOH B O   1 
HETATM 5372 O O   . HOH F 3 .   ? 17.50300 -26.41800 184.34700 1.000 16.27000 ? 753 HOH B O   1 
HETATM 5373 O O   . HOH F 3 .   ? 17.50600 -21.78600 158.43000 1.000 27.51000 ? 754 HOH B O   1 
HETATM 5374 O O   . HOH F 3 .   ? 19.75000 -26.30000 185.76500 1.000 14.61000 ? 755 HOH B O   1 
HETATM 5375 O O   . HOH F 3 .   ? 22.74900 10.36100  175.48100 1.000 29.10000 ? 756 HOH B O   1 
HETATM 5376 O O   . HOH F 3 .   ? 29.35500 10.18400  187.86200 1.000 26.98000 ? 757 HOH B O   1 
HETATM 5377 O O   . HOH F 3 .   ? -5.790   -19.169   179.259   1.000 33.35000 ? 758 HOH B O   1 
HETATM 5378 O O   . HOH F 3 .   ? 23.88800 -32.55700 184.62900 1.000 37.33000 ? 759 HOH B O   1 
HETATM 5379 O O   . HOH F 3 .   ? 28.95600 6.74000   192.24300 1.000 34.43000 ? 760 HOH B O   1 
HETATM 5380 O O   . HOH F 3 .   ? 40.65600 -24.25000 173.26800 1.000 36.79000 ? 761 HOH B O   1 
HETATM 5381 O O   . HOH F 3 .   ? 23.30800 -24.08100 155.48600 1.000 35.69000 ? 762 HOH B O   1 
HETATM 5382 O O   . HOH F 3 .   ? 26.35700 -24.31000 163.22700 1.000 21.36000 ? 763 HOH B O   1 
HETATM 5383 O O   . HOH F 3 .   ? -1.75300 -22.04200 182.98700 1.000 25.46000 ? 764 HOH B O   1 
HETATM 5384 O O   . HOH F 3 .   ? 2.29900  -1.60700  182.36400 1.000 39.88000 ? 765 HOH B O   1 
HETATM 5385 O O   . HOH F 3 .   ? -2.00400 -14.94500 165.05300 1.000 35.67000 ? 766 HOH B O   1 
HETATM 5386 O O   . HOH F 3 .   ? 25.71000 -9.57000  187.83300 1.000 33.01000 ? 767 HOH B O   1 
HETATM 5387 O O   . HOH F 3 .   ? 33.14000 -16.57200 179.25300 1.000 29.70000 ? 768 HOH B O   1 
HETATM 5388 O O   . HOH F 3 .   ? -5.37300 -20.23300 175.34700 1.000 40.31000 ? 769 HOH B O   1 
HETATM 5389 O O   . HOH F 3 .   ? 1.16100  -13.11900 162.01800 1.000 33.42000 ? 770 HOH B O   1 
HETATM 5390 O O   . HOH F 3 .   ? 27.50200 6.58500   176.54300 1.000 20.78000 ? 771 HOH B O   1 
HETATM 5391 O O   . HOH F 3 .   ? 26.76800 -24.05400 157.28400 1.000 28.37000 ? 772 HOH B O   1 
HETATM 5392 O O   . HOH F 3 .   ? 25.18100 10.51100  175.78300 1.000 27.52000 ? 773 HOH B O   1 
HETATM 5393 O O   . HOH F 3 .   ? 35.22600 -16.97800 192.38700 1.000 29.35000 ? 774 HOH B O   1 
HETATM 5394 O O   . HOH F 3 .   ? -0.82500 -26.64000 167.01600 1.000 34.45000 ? 775 HOH B O   1 
HETATM 5395 O O   . HOH F 3 .   ? 15.59100 -27.47200 186.37600 1.000 31.09000 ? 776 HOH B O   1 
HETATM 5396 O O   . HOH F 3 .   ? -1.00100 -5.41300  183.62300 1.000 35.16000 ? 777 HOH B O   1 
HETATM 5397 O O   . HOH F 3 .   ? 15.82300 -38.12600 177.38700 1.000 35.27000 ? 778 HOH B O   1 
HETATM 5398 O O   . HOH F 3 .   ? 16.62100 -33.23000 171.83800 1.000 25.27000 ? 779 HOH B O   1 
HETATM 5399 O O   . HOH F 3 .   ? 31.20500 5.11700   175.57500 1.000 31.64000 ? 780 HOH B O   1 
HETATM 5400 O O   . HOH F 3 .   ? 35.77200 -7.55300  171.11200 1.000 28.10000 ? 781 HOH B O   1 
HETATM 5401 O O   . HOH F 3 .   ? 10.83400 -23.27400 156.19000 1.000 30.72000 ? 782 HOH B O   1 
HETATM 5402 O O   . HOH F 3 .   ? 5.67500  -28.04400 161.28200 1.000 28.07000 ? 783 HOH B O   1 
HETATM 5403 O O   . HOH F 3 .   ? 7.04100  -5.75300  153.58300 1.000 33.74000 ? 784 HOH B O   1 
HETATM 5404 O O   . HOH F 3 .   ? 12.37100 -10.86300 196.51100 1.000 20.95000 ? 785 HOH B O   1 
HETATM 5405 O O   . HOH F 3 .   ? 27.99700 -3.06000  194.36900 1.000 32.16000 ? 786 HOH B O   1 
HETATM 5406 O O   . HOH F 3 .   ? 20.570   -18.051   203.381   1.000 35.45000 ? 787 HOH B O   1 
HETATM 5407 O O   . HOH F 3 .   ? 39.05000 -7.04100  184.05700 1.000 31.70000 ? 788 HOH B O   1 
HETATM 5408 O O   . HOH F 3 .   ? 24.21800 -23.43000 202.43900 1.000 34.71000 ? 789 HOH B O   1 
HETATM 5409 O O   . HOH F 3 .   ? 18.51700 -21.05100 198.77100 1.000 19.04000 ? 790 HOH B O   1 
HETATM 5410 O O   . HOH F 3 .   ? 17.93700 9.69400   190.19400 1.000 31.58000 ? 791 HOH B O   1 
HETATM 5411 O O   . HOH F 3 .   ? 4.96700  -7.38000  161.16200 1.000 17.21000 ? 792 HOH B O   1 
HETATM 5412 O O   . HOH F 3 .   ? 30.08200 -31.84000 178.53300 1.000 33.41000 ? 793 HOH B O   1 
HETATM 5413 O O   . HOH F 3 .   ? 19.12700 -31.38500 166.56800 1.000 23.43000 ? 794 HOH B O   1 
HETATM 5414 O O   . HOH F 3 .   ? 31.12200 3.55100   189.58200 1.000 33.49000 ? 795 HOH B O   1 
HETATM 5415 O O   . HOH F 3 .   ? 28.39200 3.45900   193.04100 1.000 19.67000 ? 796 HOH B O   1 
HETATM 5416 O O   . HOH F 3 .   ? 3.10400  -29.22100 161.85500 1.000 45.35000 ? 797 HOH B O   1 
HETATM 5417 O O   . HOH F 3 .   ? 25.384   -10.914   204.404   1.000 37.98000 ? 798 HOH B O   1 
HETATM 5418 O O   . HOH F 3 .   ? 17.60100 -14.74700 156.74800 1.000 21.22000 ? 799 HOH B O   1 
HETATM 5419 O O   . HOH F 3 .   ? 9.99000  -18.04300 193.06900 1.000 27.53000 ? 800 HOH B O   1 
HETATM 5420 O O   . HOH F 3 .   ? 18.31600 -30.06500 168.79000 1.000 14.64000 ? 801 HOH B O   1 
HETATM 5421 O O   . HOH F 3 .   ? 20.52500 -30.87600 164.03700 1.000 34.56000 ? 802 HOH B O   1 
HETATM 5422 O O   . HOH F 3 .   ? 18.10500 -14.44100 198.57800 1.000 14.17000 ? 803 HOH B O   1 
HETATM 5423 O O   . HOH F 3 .   ? 23.84900 -16.54800 162.14700 1.000 8.64000  ? 804 HOH B O   1 
HETATM 5424 O O   . HOH F 3 .   ? 9.81100  6.29800   175.67000 1.000 36.95000 ? 805 HOH B O   1 
HETATM 5425 O O   . HOH F 3 .   ? 40.70500 -18.22800 178.71400 1.000 33.67000 ? 806 HOH B O   1 
HETATM 5426 O O   . HOH F 3 .   ? 9.07400  -32.63800 182.96800 1.000 41.21000 ? 807 HOH B O   1 
HETATM 5427 O O   . HOH F 3 .   ? 18.15300 9.40800   179.29700 1.000 27.82000 ? 808 HOH B O   1 
HETATM 5428 O O   . HOH F 3 .   ? 40.70400 -6.58000  182.08900 1.000 32.18000 ? 809 HOH B O   1 
HETATM 5429 O O   . HOH F 3 .   ? 11.53500 -6.83800  196.37700 1.000 31.52000 ? 810 HOH B O   1 
HETATM 5430 O O   . HOH F 3 .   ? 12.22400 -30.93100 167.20200 1.000 25.21000 ? 811 HOH B O   1 
HETATM 5431 O O   . HOH F 3 .   ? 26.09600 -32.12200 181.14700 1.000 20.04000 ? 812 HOH B O   1 
HETATM 5432 O O   . HOH F 3 .   ? 17.263   -7.807    197.313   1.000 26.69000 ? 813 HOH B O   1 
HETATM 5433 O O   . HOH F 3 .   ? 23.97500 -10.55700 189.18700 1.000 30.96000 ? 814 HOH B O   1 
HETATM 5434 O O   . HOH F 3 .   ? 37.65300 -26.24800 176.26300 1.000 26.39000 ? 815 HOH B O   1 
HETATM 5435 O O   . HOH F 3 .   ? 15.38100 -19.26700 193.78600 1.000 18.19000 ? 816 HOH B O   1 
HETATM 5436 O O   . HOH F 3 .   ? 14.67200 -11.37800 155.83600 1.000 11.92000 ? 817 HOH B O   1 
HETATM 5437 O O   . HOH F 3 .   ? 20.31600 12.36300  173.50700 1.000 34.21000 ? 818 HOH B O   1 
HETATM 5438 O O   . HOH F 3 .   ? 33.43400 -1.37600  193.41100 1.000 34.17000 ? 819 HOH B O   1 
HETATM 5439 O O   . HOH F 3 .   ? 38.35200 -11.95000 189.67200 1.000 32.63000 ? 820 HOH B O   1 
HETATM 5440 O O   . HOH F 3 .   ? 7.47900  -12.60000 193.85700 1.000 38.05000 ? 821 HOH B O   1 
HETATM 5441 O O   . HOH F 3 .   ? 28.50800 2.89300   199.82100 1.000 36.29000 ? 822 HOH B O   1 
HETATM 5442 O O   . HOH F 3 .   ? 31.38900 -29.36700 167.40100 1.000 34.29000 ? 823 HOH B O   1 
HETATM 5443 O O   . HOH F 3 .   ? 32.147   -24.107   189.647   1.000 17.29000 ? 824 HOH B O   1 
HETATM 5444 O O   . HOH F 3 .   ? 19.63400 10.98100  191.69200 1.000 35.91000 ? 825 HOH B O   1 
HETATM 5445 O O   . HOH F 3 .   ? 4.41200  -3.16500  162.92500 1.000 28.45000 ? 826 HOH B O   1 
HETATM 5446 O O   . HOH F 3 .   ? 7.79300  -11.40300 188.55600 1.000 24.03000 ? 827 HOH B O   1 
HETATM 5447 O O   . HOH F 3 .   ? 1.61900  -4.16700  185.15200 1.000 34.74000 ? 828 HOH B O   1 
HETATM 5448 O O   . HOH F 3 .   ? 12.84200 -12.73700 157.34500 1.000 14.66000 ? 829 HOH B O   1 
HETATM 5449 O O   . HOH F 3 .   ? 20.62800 8.33800   175.91600 1.000 16.56000 ? 830 HOH B O   1 
HETATM 5450 O O   . HOH F 3 .   ? 10.00500 -30.39500 183.06700 1.000 30.87000 ? 831 HOH B O   1 
HETATM 5451 O O   . HOH F 3 .   ? 1.99100  -16.13800 158.27400 1.000 34.22000 ? 832 HOH B O   1 
HETATM 5452 O O   . HOH F 3 .   ? 7.57800  -30.17700 162.10000 1.000 27.95000 ? 833 HOH B O   1 
HETATM 5453 O O   . HOH F 3 .   ? 27.10800 -31.79000 167.96900 1.000 33.87000 ? 834 HOH B O   1 
HETATM 5454 O O   . HOH F 3 .   ? 27.41600 11.58300  186.77200 1.000 33.07000 ? 835 HOH B O   1 
HETATM 5455 O O   . HOH F 3 .   ? 21.98000 13.64900  171.98100 1.000 35.71000 ? 836 HOH B O   1 
HETATM 5456 O O   . HOH F 3 .   ? 35.69300 6.93000   186.38700 1.000 38.59000 ? 837 HOH B O   1 
HETATM 5457 O O   . HOH F 3 .   ? -3.58800 -24.88700 173.75500 1.000 36.96000 ? 838 HOH B O   1 
HETATM 5458 O O   . HOH F 3 .   ? 35.02000 -14.04600 180.67500 1.000 35.56000 ? 839 HOH B O   1 
HETATM 5459 O O   . HOH F 3 .   ? 16.41500 -21.46800 197.19600 1.000 17.39000 ? 840 HOH B O   1 
HETATM 5460 O O   . HOH F 3 .   ? 39.79700 -24.36800 165.92500 1.000 36.38000 ? 841 HOH B O   1 
HETATM 5461 O O   . HOH F 3 .   ? 39.52500 -20.24900 166.96500 1.000 34.80000 ? 842 HOH B O   1 
HETATM 5462 O O   . HOH F 3 .   ? 27.77900 -23.45300 165.34400 1.000 23.13000 ? 843 HOH B O   1 
HETATM 5463 O O   . HOH F 3 .   ? 3.30700  -11.99600 188.89800 1.000 32.01000 ? 844 HOH B O   1 
HETATM 5464 O O   . HOH F 3 .   ? 17.67400 -28.97100 183.36400 1.000 25.04000 ? 845 HOH B O   1 
HETATM 5465 O O   . HOH F 3 .   ? 39.95700 -13.79800 172.06200 1.000 33.21000 ? 846 HOH B O   1 
HETATM 5466 O O   . HOH F 3 .   ? 37.137   -16.255   194.596   1.000 20.22000 ? 847 HOH B O   1 
HETATM 5467 O O   . HOH F 3 .   ? 21.264   7.503     201.417   1.000 39.58000 ? 848 HOH B O   1 
HETATM 5468 O O   . HOH F 3 .   ? 17.48800 -22.73300 192.56600 1.000 27.55000 ? 849 HOH B O   1 
HETATM 5469 O O   . HOH F 3 .   ? 22.51200 13.64900  182.75000 1.000 32.36000 ? 850 HOH B O   1 
HETATM 5470 O O   . HOH F 3 .   ? 8.86200  -24.95700 185.56500 1.000 28.16000 ? 851 HOH B O   1 
HETATM 5471 O O   . HOH F 3 .   ? 16.49800 -32.26200 165.46200 1.000 38.58000 ? 852 HOH B O   1 
HETATM 5472 O O   . HOH F 3 .   ? 23.67100 -33.95200 174.63700 1.000 30.52000 ? 853 HOH B O   1 
HETATM 5473 O O   . HOH F 3 .   ? 31.40600 13.60700  184.50000 1.000 45.68000 ? 854 HOH B O   1 
HETATM 5474 O O   . HOH F 3 .   ? 5.37600  -10.48800 161.67200 1.000 25.38000 ? 855 HOH B O   1 
HETATM 5475 O O   . HOH F 3 .   ? -1.61500 -26.79300 181.56800 1.000 40.52000 ? 856 HOH B O   1 
HETATM 5476 O O   . HOH F 3 .   ? 27.59200 9.27000   175.84000 1.000 21.55000 ? 857 HOH B O   1 
HETATM 5477 O O   . HOH F 3 .   ? -4.668   -23.697   180.191   1.000 28.32000 ? 858 HOH B O   1 
HETATM 5478 O O   . HOH F 3 .   ? -3.838   -20.883   179.718   1.000 23.96000 ? 859 HOH B O   1 
HETATM 5479 O O   . HOH F 3 .   ? 28.80200 -25.89500 165.79100 1.000 26.95000 ? 860 HOH B O   1 
HETATM 5480 O O   . HOH F 3 .   ? 34.15000 -30.49100 171.34400 1.000 33.30000 ? 861 HOH B O   1 
HETATM 5481 O O   . HOH F 3 .   ? 14.31800 7.21700   190.30200 1.000 33.54000 ? 862 HOH B O   1 
HETATM 5482 O O   . HOH F 3 .   ? 14.86400 -21.87700 156.89400 1.000 26.03000 ? 863 HOH B O   1 
HETATM 5483 O O   . HOH F 3 .   ? 19.75000 -22.79700 200.56300 1.000 33.47000 ? 864 HOH B O   1 
HETATM 5484 O O   . HOH F 3 .   ? 5.99600  -27.47700 158.43300 1.000 38.93000 ? 865 HOH B O   1 
HETATM 5485 O O   . HOH F 3 .   ? 12.61400 7.85100   180.33500 1.000 32.90000 ? 866 HOH B O   1 
HETATM 5486 O O   . HOH F 3 .   ? 31.20700 -13.05800 154.27000 1.000 37.47000 ? 867 HOH B O   1 
HETATM 5487 O O   . HOH F 3 .   ? 10.27100 -30.13000 162.95600 1.000 18.31000 ? 868 HOH B O   1 
HETATM 5488 O O   . HOH F 3 .   ? 16.03900 -31.55300 169.22000 1.000 20.86000 ? 869 HOH B O   1 
HETATM 5489 O O   . HOH F 3 .   ? 13.45100 -28.27500 185.06800 1.000 31.80000 ? 870 HOH B O   1 
HETATM 5490 O O   . HOH F 3 .   ? 18.62200 10.41000  181.97400 1.000 32.85000 ? 871 HOH B O   1 
HETATM 5491 O O   . HOH F 3 .   ? 19.03700 -33.99000 170.86700 1.000 33.95000 ? 872 HOH B O   1 
HETATM 5492 O O   . HOH F 3 .   ? 41.48300 -20.10400 177.36600 1.000 29.49000 ? 873 HOH B O   1 
HETATM 5493 O O   . HOH F 3 .   ? 36.09100 -11.16600 158.41800 1.000 41.96000 ? 874 HOH B O   1 
HETATM 5494 O O   . HOH F 3 .   ? -7.52600 -14.13400 182.39300 1.000 39.20000 ? 875 HOH B O   1 
HETATM 5495 O O   . HOH F 3 .   ? 33.044   -26.801   189.237   1.000 13.09000 ? 876 HOH B O   1 
HETATM 5496 O O   . HOH F 3 .   ? 16.56700 7.53300   191.22500 1.000 29.27000 ? 877 HOH B O   1 
HETATM 5497 O O   . HOH F 3 .   ? 33.60000 5.35400   178.54600 1.000 34.44000 ? 878 HOH B O   1 
HETATM 5498 O O   . HOH F 3 .   ? 39.941   -22.620   177.663   1.000 23.13000 ? 879 HOH B O   1 
HETATM 5499 O O   . HOH F 3 .   ? 4.05500  1.36200   165.73400 1.000 38.13000 ? 880 HOH B O   1 
HETATM 5500 O O   . HOH F 3 .   ? 12.65000 -27.15400 188.64100 1.000 43.06000 ? 881 HOH B O   1 
HETATM 5501 O O   . HOH F 3 .   ? 31.04300 -18.33900 178.74500 1.000 18.03000 ? 882 HOH B O   1 
HETATM 5502 O O   . HOH F 3 .   ? 31.00700 0.27000   193.68000 1.000 29.06000 ? 883 HOH B O   1 
HETATM 5503 O O   . HOH F 3 .   ? 4.34800  -1.16100  186.48400 1.000 23.98000 ? 884 HOH B O   1 
HETATM 5504 O O   . HOH F 3 .   ? 30.05200 7.45500   187.95400 1.000 34.02000 ? 885 HOH B O   1 
HETATM 5505 O O   . HOH F 3 .   ? 11.18900 -26.85700 186.43700 1.000 32.86000 ? 886 HOH B O   1 
HETATM 5506 O O   . HOH F 3 .   ? 37.66600 -6.52300  171.90300 1.000 34.29000 ? 887 HOH B O   1 
HETATM 5507 O O   . HOH F 3 .   ? 13.98500 -17.80000 195.86600 1.000 11.01000 ? 888 HOH B O   1 
HETATM 5508 O O   . HOH F 3 .   ? 18.64600 -23.31200 154.43300 1.000 27.32000 ? 889 HOH B O   1 
HETATM 5509 O O   . HOH F 3 .   ? 35.93700 -7.71300  166.07400 1.000 25.75000 ? 890 HOH B O   1 
HETATM 5510 O O   . HOH F 3 .   ? 23.82300 12.03200  189.11800 1.000 26.38000 ? 891 HOH B O   1 
HETATM 5511 O O   . HOH F 3 .   ? 13.68200 8.59000   188.53500 1.000 35.24000 ? 892 HOH B O   1 
HETATM 5512 O O   . HOH F 3 .   ? 4.20700  -10.05500 157.83100 1.000 41.08000 ? 893 HOH B O   1 
HETATM 5513 O O   . HOH F 3 .   ? 3.54200  -6.51700  159.27100 1.000 28.87000 ? 894 HOH B O   1 
HETATM 5514 O O   . HOH F 3 .   ? 37.61800 -13.90900 169.10000 1.000 28.26000 ? 895 HOH B O   1 
HETATM 5515 O O   . HOH F 3 .   ? 5.49300  -6.93600  165.30000 1.000 20.87000 ? 896 HOH B O   1 
HETATM 5516 O O   . HOH F 3 .   ? 6.18100  -0.49200  173.21800 1.000 17.35000 ? 897 HOH B O   1 
HETATM 5517 O O   . HOH F 3 .   ? 21.20100 -32.14600 171.00500 1.000 19.99000 ? 898 HOH B O   1 
HETATM 5518 O O   . HOH F 3 .   ? 9.06100  -6.42800  149.90900 1.000 31.40000 ? 899 HOH B O   1 
HETATM 5519 O O   . HOH F 3 .   ? 29.79100 -4.25100  192.71200 1.000 32.24000 ? 900 HOH B O   1 
HETATM 5520 O O   . HOH F 3 .   ? 27.30200 -28.01600 165.80900 1.000 30.92000 ? 901 HOH B O   1 
HETATM 5521 O O   . HOH F 3 .   ? 7.34300  -12.36400 160.90000 1.000 19.48000 ? 902 HOH B O   1 
HETATM 5522 O O   . HOH F 3 .   ? 37.80900 -14.14200 191.17600 1.000 20.43000 ? 903 HOH B O   1 
HETATM 5523 O O   . HOH F 3 .   ? 10.72300 -33.99200 170.22500 1.000 34.75000 ? 904 HOH B O   1 
HETATM 5524 O O   . HOH F 3 .   ? 41.51300 -18.09200 172.91000 1.000 30.14000 ? 905 HOH B O   1 
HETATM 5525 O O   . HOH F 3 .   ? -2.63600 -20.49500 174.85000 1.000 37.20000 ? 906 HOH B O   1 
HETATM 5526 O O   . HOH F 3 .   ? 29.33200 4.12700   195.66000 1.000 29.64000 ? 907 HOH B O   1 
HETATM 5527 O O   . HOH F 3 .   ? 23.89700 -11.20500 194.30300 1.000 42.26000 ? 908 HOH B O   1 
HETATM 5528 O O   . HOH F 3 .   ? 25.98900 -26.96900 163.16000 1.000 21.65000 ? 909 HOH B O   1 
HETATM 5529 O O   . HOH F 3 .   ? -1.45600 -6.99100  177.34800 1.000 23.87000 ? 910 HOH B O   1 
HETATM 5530 O O   . HOH F 3 .   ? 34.67000 -10.58800 163.20900 1.000 25.65000 ? 911 HOH B O   1 
HETATM 5531 O O   . HOH F 3 .   ? 18.412   -18.569   199.957   1.000 15.78000 ? 912 HOH B O   1 
HETATM 5532 O O   . HOH F 3 .   ? 23.10900 -12.66300 149.24600 1.000 20.26000 ? 913 HOH B O   1 
HETATM 5533 O O   . HOH F 3 .   ? 34.385   -16.862   204.065   1.000 30.67000 ? 914 HOH B O   1 
HETATM 5534 O O   . HOH F 3 .   ? 13.87800 -31.25800 164.97200 1.000 27.86000 ? 915 HOH B O   1 
HETATM 5535 O O   . HOH F 3 .   ? 36.76900 -9.32000  169.50200 1.000 32.15000 ? 916 HOH B O   1 
HETATM 5536 O O   . HOH F 3 .   ? 8.56200  -12.34900 157.19000 1.000 20.09000 ? 917 HOH B O   1 
HETATM 5537 O O   . HOH F 3 .   ? 6.64200  -11.02400 155.77100 1.000 36.51000 ? 918 HOH B O   1 
HETATM 5538 O O   . HOH F 3 .   ? 21.19400 -30.60800 184.53900 1.000 24.65000 ? 919 HOH B O   1 
HETATM 5539 O O   . HOH F 3 .   ? 29.09000 5.51600   189.42100 1.000 35.81000 ? 920 HOH B O   1 
HETATM 5540 O O   . HOH F 3 .   ? 27.65600 -32.37400 174.84800 1.000 21.79000 ? 921 HOH B O   1 
HETATM 5541 O O   . HOH F 3 .   ? 20.73800 -31.79300 181.93400 1.000 32.38000 ? 922 HOH B O   1 
HETATM 5542 O O   . HOH F 3 .   ? 26.46800 -34.47000 174.46900 1.000 38.75000 ? 923 HOH B O   1 
HETATM 5543 O O   . HOH F 3 .   ? 28.968   -34.946   180.402   1.000 39.22000 ? 924 HOH B O   1 
HETATM 5544 O O   . HOH F 3 .   ? 28.49900 -24.64200 158.77500 1.000 40.55000 ? 925 HOH B O   1 
HETATM 5545 O O   . HOH F 3 .   ? 42.02200 -19.98300 174.71100 1.000 38.46000 ? 926 HOH B O   1 
HETATM 5546 O O   . HOH F 3 .   ? 10.58100 -16.22300 156.43100 1.000 31.76000 ? 927 HOH B O   1 
HETATM 5547 O O   . HOH F 3 .   ? 9.26400  -28.58800 185.42700 1.000 35.05000 ? 928 HOH B O   1 
HETATM 5548 O O   . HOH F 3 .   ? 35.95100 -10.14700 167.56700 1.000 25.55000 ? 929 HOH B O   1 
HETATM 5549 O O   . HOH F 3 .   ? 4.70900  -9.62200  164.38200 1.000 27.97000 ? 930 HOH B O   1 
HETATM 5550 O O   . HOH F 3 .   ? 22.86000 -33.64500 172.27900 1.000 30.23000 ? 931 HOH B O   1 
HETATM 5551 O O   . HOH F 3 .   ? 31.38700 2.29600   195.64400 1.000 35.35000 ? 932 HOH B O   1 
HETATM 5552 O O   . HOH F 3 .   ? 10.61100 -36.52700 170.99200 1.000 33.66000 ? 933 HOH B O   1 
HETATM 5553 O O   . HOH F 3 .   ? 2.86200  -3.16400  160.48100 1.000 36.56000 ? 934 HOH B O   1 
HETATM 5554 O O   . HOH F 3 .   ? 15.88600 -33.71400 167.57100 1.000 35.87000 ? 935 HOH B O   1 
HETATM 5555 O O   . HOH F 3 .   ? 19.84100 -23.10200 151.84700 1.000 45.54000 ? 936 HOH B O   1 
HETATM 5556 O O   . HOH F 3 .   ? 19.55800 -31.53800 186.60400 1.000 35.86000 ? 937 HOH B O   1 
# 
