data_9L9W
# 
_entry.id   9L9W 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9L9W         pdb_00009l9w 10.2210/pdb9l9w/pdb 
WWPDB D_1300055260 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-03-12 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9L9W 
_pdbx_database_status.recvd_initial_deposition_date   2024-12-31 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              liangliu2019@xmu.edu.cn 
_pdbx_contact_author.name_first         Liang 
_pdbx_contact_author.name_last          Liu 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-5379-0638 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Hu, R.'   1 ? 
'Guo, C.'  2 ? 
'Liu, X.'  3 ? 
'Chen, J.' 4 ? 
'Liu, L.'  5 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nucleic Acids Res.' 
_citation.journal_id_ASTM           NARHAD 
_citation.journal_id_CSD            0389 
_citation.journal_id_ISSN           1362-4962 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            53 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Structural basis of ssDNA-guided NADase activation of prokaryotic SPARTA system.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1093/nar/gkaf110 
_citation.pdbx_database_id_PubMed   39997222 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Hu, R.'   1  ?                   
primary 'Guo, C.'  2  ?                   
primary 'Liu, X.'  3  ?                   
primary 'Lin, Y.'  4  ?                   
primary 'Yang, Z.' 5  ?                   
primary 'Li, Z.'   6  ?                   
primary 'Yang, Y.' 7  ?                   
primary 'Ma, E.'   8  ?                   
primary 'Li, Y.'   9  ?                   
primary 'Chen, J.' 10 ?                   
primary 'Liu, L.'  11 0000-0002-5379-0638 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Piwi domain-containing protein'                                                 58304.848 1 ? ? ? ? 
2 polymer     man 'TIR domain-containing protein'                                                  49906.344 1 ? ? ? ? 
3 polymer     syn 
;DNA (5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3')
;
6588.266  1 ? ? ? ? 
4 polymer     syn 
;DNA (5'-D(*T*AP*TP*AP*CP*AP*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*CP*AP*T)-3')
;
5996.919  1 ? ? ? ? 
5 non-polymer syn 'MAGNESIUM ION'                                                                  24.305    1 ? ? ? ? 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)'        no no 
;MKELIYIEEPSILFAHGQKCTDPRDGLALFGPLNQIYGIKSGVVGTQKGLQIFKSYLDKIQKPIYNHNNITRPMFPGFEA
VFGCKWESQNIVFKEITDEEIRRYLFNASTHKRTYDLVTLFNDKIITANKNDEERVDVWFVIVPEEIYKYCRPNSVLPNE
LVQTKSLISKSKAKSFRYTPTLFEEFNKKLKEVEKEAKTYNYDAQFHDQLKARLLEHTIPTQILRESTLAWRDFKNTFGA
PIRDFSKIEGHLAWTISTAAYYKAGGKPWKLGDIRPGVCYLGLVYKKIEKSKNPQNACCAAQMFLDNGDGTVFKGEVGPW
YNPEKGEYHLKPKEAKALLTQALESYKEQNKSYPKEVFIHARTRFNDEEWNAFNEVTPKNTNLVGVTITKSKPLKLYKTE
GAFPIMRGNAYIVDEKKAFLWTLGFVPKLQSTLSMEVPNPIFIEINKGEAEIQQVLKDILALTKLNYNACIYADGEPVTL
RFANKIGEILTASTEIKTPPLAFKYYI
;
;MKELIYIEEPSILFAHGQKCTDPRDGLALFGPLNQIYGIKSGVVGTQKGLQIFKSYLDKIQKPIYNHNNITRPMFPGFEA
VFGCKWESQNIVFKEITDEEIRRYLFNASTHKRTYDLVTLFNDKIITANKNDEERVDVWFVIVPEEIYKYCRPNSVLPNE
LVQTKSLISKSKAKSFRYTPTLFEEFNKKLKEVEKEAKTYNYDAQFHDQLKARLLEHTIPTQILRESTLAWRDFKNTFGA
PIRDFSKIEGHLAWTISTAAYYKAGGKPWKLGDIRPGVCYLGLVYKKIEKSKNPQNACCAAQMFLDNGDGTVFKGEVGPW
YNPEKGEYHLKPKEAKALLTQALESYKEQNKSYPKEVFIHARTRFNDEEWNAFNEVTPKNTNLVGVTITKSKPLKLYKTE
GAFPIMRGNAYIVDEKKAFLWTLGFVPKLQSTLSMEVPNPIFIEINKGEAEIQQVLKDILALTKLNYNACIYADGEPVTL
RFANKIGEILTASTEIKTPPLAFKYYI
;
A ? 
2 'polypeptide(L)'        no no 
;MRNKIFISHATPEDDDFTRWLSLKLIGLGYEVWCDILFLDKGVDFWSTIEKEIRENTCKFLIVSSTAGNKREGVLKELAV
ATKVKKHLQDDMFIIPLAIDENLSYDDINIEIVRLNAIDFKKSWAKGLQDLLDAFEKQNVPKKPPDHSKSNLLYQQIFLH
DKQAIEKEETYDSNWFPIISFPNELRFHRYDWRLPKQFDVRTLAFPAIRYKEYLCTFAWEYDFIHQLPKTETYNGQESIR
ISTSDILSGRYDTDFIRNYECQRLIVQLINKAFELRMKDKNVREYQMSKTFAYWIEKGKLEKDKFEKIKLVGKQKNKYWH
FGISAAGKLYPSPVLMVSSHIIFTMDGINLIKSKSIQHSSRRKQGKNWWNDKWREKLLAFIRFLSDDQNAIYLNVGSEEK
ILISNKPLKFFGKMSYVTPSE
;
;MRNKIFISHATPEDDDFTRWLSLKLIGLGYEVWCDILFLDKGVDFWSTIEKEIRENTCKFLIVSSTAGNKREGVLKELAV
ATKVKKHLQDDMFIIPLAIDENLSYDDINIEIVRLNAIDFKKSWAKGLQDLLDAFEKQNVPKKPPDHSKSNLLYQQIFLH
DKQAIEKEETYDSNWFPIISFPNELRFHRYDWRLPKQFDVRTLAFPAIRYKEYLCTFAWEYDFIHQLPKTETYNGQESIR
ISTSDILSGRYDTDFIRNYECQRLIVQLINKAFELRMKDKNVREYQMSKTFAYWIEKGKLEKDKFEKIKLVGKQKNKYWH
FGISAAGKLYPSPVLMVSSHIIFTMDGINLIKSKSIQHSSRRKQGKNWWNDKWREKLLAFIRFLSDDQNAIYLNVGSEEK
ILISNKPLKFFGKMSYVTPSE
;
B ? 
3 polydeoxyribonucleotide no no 
;(DT)(DG)(DA)(DG)(DG)(DT)(DA)(DG)(DT)(DA)(DG)(DG)(DT)(DT)(DG)(DT)(DA)(DT)(DA)(DG)
(DT)
;
TGAGGTAGTAGGTTGTATAGT C ? 
4 polydeoxyribonucleotide no no '(DT)(DA)(DT)(DA)(DC)(DA)(DA)(DC)(DC)(DT)(DA)(DC)(DT)(DA)(DC)(DC)(DT)(DC)(DA)(DT)' 
TATACAACCTACTACCTCAT D ? 
# 
_pdbx_entity_nonpoly.entity_id   5 
_pdbx_entity_nonpoly.name        'MAGNESIUM ION' 
_pdbx_entity_nonpoly.comp_id     MG 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   LYS n 
1 3   GLU n 
1 4   LEU n 
1 5   ILE n 
1 6   TYR n 
1 7   ILE n 
1 8   GLU n 
1 9   GLU n 
1 10  PRO n 
1 11  SER n 
1 12  ILE n 
1 13  LEU n 
1 14  PHE n 
1 15  ALA n 
1 16  HIS n 
1 17  GLY n 
1 18  GLN n 
1 19  LYS n 
1 20  CYS n 
1 21  THR n 
1 22  ASP n 
1 23  PRO n 
1 24  ARG n 
1 25  ASP n 
1 26  GLY n 
1 27  LEU n 
1 28  ALA n 
1 29  LEU n 
1 30  PHE n 
1 31  GLY n 
1 32  PRO n 
1 33  LEU n 
1 34  ASN n 
1 35  GLN n 
1 36  ILE n 
1 37  TYR n 
1 38  GLY n 
1 39  ILE n 
1 40  LYS n 
1 41  SER n 
1 42  GLY n 
1 43  VAL n 
1 44  VAL n 
1 45  GLY n 
1 46  THR n 
1 47  GLN n 
1 48  LYS n 
1 49  GLY n 
1 50  LEU n 
1 51  GLN n 
1 52  ILE n 
1 53  PHE n 
1 54  LYS n 
1 55  SER n 
1 56  TYR n 
1 57  LEU n 
1 58  ASP n 
1 59  LYS n 
1 60  ILE n 
1 61  GLN n 
1 62  LYS n 
1 63  PRO n 
1 64  ILE n 
1 65  TYR n 
1 66  ASN n 
1 67  HIS n 
1 68  ASN n 
1 69  ASN n 
1 70  ILE n 
1 71  THR n 
1 72  ARG n 
1 73  PRO n 
1 74  MET n 
1 75  PHE n 
1 76  PRO n 
1 77  GLY n 
1 78  PHE n 
1 79  GLU n 
1 80  ALA n 
1 81  VAL n 
1 82  PHE n 
1 83  GLY n 
1 84  CYS n 
1 85  LYS n 
1 86  TRP n 
1 87  GLU n 
1 88  SER n 
1 89  GLN n 
1 90  ASN n 
1 91  ILE n 
1 92  VAL n 
1 93  PHE n 
1 94  LYS n 
1 95  GLU n 
1 96  ILE n 
1 97  THR n 
1 98  ASP n 
1 99  GLU n 
1 100 GLU n 
1 101 ILE n 
1 102 ARG n 
1 103 ARG n 
1 104 TYR n 
1 105 LEU n 
1 106 PHE n 
1 107 ASN n 
1 108 ALA n 
1 109 SER n 
1 110 THR n 
1 111 HIS n 
1 112 LYS n 
1 113 ARG n 
1 114 THR n 
1 115 TYR n 
1 116 ASP n 
1 117 LEU n 
1 118 VAL n 
1 119 THR n 
1 120 LEU n 
1 121 PHE n 
1 122 ASN n 
1 123 ASP n 
1 124 LYS n 
1 125 ILE n 
1 126 ILE n 
1 127 THR n 
1 128 ALA n 
1 129 ASN n 
1 130 LYS n 
1 131 ASN n 
1 132 ASP n 
1 133 GLU n 
1 134 GLU n 
1 135 ARG n 
1 136 VAL n 
1 137 ASP n 
1 138 VAL n 
1 139 TRP n 
1 140 PHE n 
1 141 VAL n 
1 142 ILE n 
1 143 VAL n 
1 144 PRO n 
1 145 GLU n 
1 146 GLU n 
1 147 ILE n 
1 148 TYR n 
1 149 LYS n 
1 150 TYR n 
1 151 CYS n 
1 152 ARG n 
1 153 PRO n 
1 154 ASN n 
1 155 SER n 
1 156 VAL n 
1 157 LEU n 
1 158 PRO n 
1 159 ASN n 
1 160 GLU n 
1 161 LEU n 
1 162 VAL n 
1 163 GLN n 
1 164 THR n 
1 165 LYS n 
1 166 SER n 
1 167 LEU n 
1 168 ILE n 
1 169 SER n 
1 170 LYS n 
1 171 SER n 
1 172 LYS n 
1 173 ALA n 
1 174 LYS n 
1 175 SER n 
1 176 PHE n 
1 177 ARG n 
1 178 TYR n 
1 179 THR n 
1 180 PRO n 
1 181 THR n 
1 182 LEU n 
1 183 PHE n 
1 184 GLU n 
1 185 GLU n 
1 186 PHE n 
1 187 ASN n 
1 188 LYS n 
1 189 LYS n 
1 190 LEU n 
1 191 LYS n 
1 192 GLU n 
1 193 VAL n 
1 194 GLU n 
1 195 LYS n 
1 196 GLU n 
1 197 ALA n 
1 198 LYS n 
1 199 THR n 
1 200 TYR n 
1 201 ASN n 
1 202 TYR n 
1 203 ASP n 
1 204 ALA n 
1 205 GLN n 
1 206 PHE n 
1 207 HIS n 
1 208 ASP n 
1 209 GLN n 
1 210 LEU n 
1 211 LYS n 
1 212 ALA n 
1 213 ARG n 
1 214 LEU n 
1 215 LEU n 
1 216 GLU n 
1 217 HIS n 
1 218 THR n 
1 219 ILE n 
1 220 PRO n 
1 221 THR n 
1 222 GLN n 
1 223 ILE n 
1 224 LEU n 
1 225 ARG n 
1 226 GLU n 
1 227 SER n 
1 228 THR n 
1 229 LEU n 
1 230 ALA n 
1 231 TRP n 
1 232 ARG n 
1 233 ASP n 
1 234 PHE n 
1 235 LYS n 
1 236 ASN n 
1 237 THR n 
1 238 PHE n 
1 239 GLY n 
1 240 ALA n 
1 241 PRO n 
1 242 ILE n 
1 243 ARG n 
1 244 ASP n 
1 245 PHE n 
1 246 SER n 
1 247 LYS n 
1 248 ILE n 
1 249 GLU n 
1 250 GLY n 
1 251 HIS n 
1 252 LEU n 
1 253 ALA n 
1 254 TRP n 
1 255 THR n 
1 256 ILE n 
1 257 SER n 
1 258 THR n 
1 259 ALA n 
1 260 ALA n 
1 261 TYR n 
1 262 TYR n 
1 263 LYS n 
1 264 ALA n 
1 265 GLY n 
1 266 GLY n 
1 267 LYS n 
1 268 PRO n 
1 269 TRP n 
1 270 LYS n 
1 271 LEU n 
1 272 GLY n 
1 273 ASP n 
1 274 ILE n 
1 275 ARG n 
1 276 PRO n 
1 277 GLY n 
1 278 VAL n 
1 279 CYS n 
1 280 TYR n 
1 281 LEU n 
1 282 GLY n 
1 283 LEU n 
1 284 VAL n 
1 285 TYR n 
1 286 LYS n 
1 287 LYS n 
1 288 ILE n 
1 289 GLU n 
1 290 LYS n 
1 291 SER n 
1 292 LYS n 
1 293 ASN n 
1 294 PRO n 
1 295 GLN n 
1 296 ASN n 
1 297 ALA n 
1 298 CYS n 
1 299 CYS n 
1 300 ALA n 
1 301 ALA n 
1 302 GLN n 
1 303 MET n 
1 304 PHE n 
1 305 LEU n 
1 306 ASP n 
1 307 ASN n 
1 308 GLY n 
1 309 ASP n 
1 310 GLY n 
1 311 THR n 
1 312 VAL n 
1 313 PHE n 
1 314 LYS n 
1 315 GLY n 
1 316 GLU n 
1 317 VAL n 
1 318 GLY n 
1 319 PRO n 
1 320 TRP n 
1 321 TYR n 
1 322 ASN n 
1 323 PRO n 
1 324 GLU n 
1 325 LYS n 
1 326 GLY n 
1 327 GLU n 
1 328 TYR n 
1 329 HIS n 
1 330 LEU n 
1 331 LYS n 
1 332 PRO n 
1 333 LYS n 
1 334 GLU n 
1 335 ALA n 
1 336 LYS n 
1 337 ALA n 
1 338 LEU n 
1 339 LEU n 
1 340 THR n 
1 341 GLN n 
1 342 ALA n 
1 343 LEU n 
1 344 GLU n 
1 345 SER n 
1 346 TYR n 
1 347 LYS n 
1 348 GLU n 
1 349 GLN n 
1 350 ASN n 
1 351 LYS n 
1 352 SER n 
1 353 TYR n 
1 354 PRO n 
1 355 LYS n 
1 356 GLU n 
1 357 VAL n 
1 358 PHE n 
1 359 ILE n 
1 360 HIS n 
1 361 ALA n 
1 362 ARG n 
1 363 THR n 
1 364 ARG n 
1 365 PHE n 
1 366 ASN n 
1 367 ASP n 
1 368 GLU n 
1 369 GLU n 
1 370 TRP n 
1 371 ASN n 
1 372 ALA n 
1 373 PHE n 
1 374 ASN n 
1 375 GLU n 
1 376 VAL n 
1 377 THR n 
1 378 PRO n 
1 379 LYS n 
1 380 ASN n 
1 381 THR n 
1 382 ASN n 
1 383 LEU n 
1 384 VAL n 
1 385 GLY n 
1 386 VAL n 
1 387 THR n 
1 388 ILE n 
1 389 THR n 
1 390 LYS n 
1 391 SER n 
1 392 LYS n 
1 393 PRO n 
1 394 LEU n 
1 395 LYS n 
1 396 LEU n 
1 397 TYR n 
1 398 LYS n 
1 399 THR n 
1 400 GLU n 
1 401 GLY n 
1 402 ALA n 
1 403 PHE n 
1 404 PRO n 
1 405 ILE n 
1 406 MET n 
1 407 ARG n 
1 408 GLY n 
1 409 ASN n 
1 410 ALA n 
1 411 TYR n 
1 412 ILE n 
1 413 VAL n 
1 414 ASP n 
1 415 GLU n 
1 416 LYS n 
1 417 LYS n 
1 418 ALA n 
1 419 PHE n 
1 420 LEU n 
1 421 TRP n 
1 422 THR n 
1 423 LEU n 
1 424 GLY n 
1 425 PHE n 
1 426 VAL n 
1 427 PRO n 
1 428 LYS n 
1 429 LEU n 
1 430 GLN n 
1 431 SER n 
1 432 THR n 
1 433 LEU n 
1 434 SER n 
1 435 MET n 
1 436 GLU n 
1 437 VAL n 
1 438 PRO n 
1 439 ASN n 
1 440 PRO n 
1 441 ILE n 
1 442 PHE n 
1 443 ILE n 
1 444 GLU n 
1 445 ILE n 
1 446 ASN n 
1 447 LYS n 
1 448 GLY n 
1 449 GLU n 
1 450 ALA n 
1 451 GLU n 
1 452 ILE n 
1 453 GLN n 
1 454 GLN n 
1 455 VAL n 
1 456 LEU n 
1 457 LYS n 
1 458 ASP n 
1 459 ILE n 
1 460 LEU n 
1 461 ALA n 
1 462 LEU n 
1 463 THR n 
1 464 LYS n 
1 465 LEU n 
1 466 ASN n 
1 467 TYR n 
1 468 ASN n 
1 469 ALA n 
1 470 CYS n 
1 471 ILE n 
1 472 TYR n 
1 473 ALA n 
1 474 ASP n 
1 475 GLY n 
1 476 GLU n 
1 477 PRO n 
1 478 VAL n 
1 479 THR n 
1 480 LEU n 
1 481 ARG n 
1 482 PHE n 
1 483 ALA n 
1 484 ASN n 
1 485 LYS n 
1 486 ILE n 
1 487 GLY n 
1 488 GLU n 
1 489 ILE n 
1 490 LEU n 
1 491 THR n 
1 492 ALA n 
1 493 SER n 
1 494 THR n 
1 495 GLU n 
1 496 ILE n 
1 497 LYS n 
1 498 THR n 
1 499 PRO n 
1 500 PRO n 
1 501 LEU n 
1 502 ALA n 
1 503 PHE n 
1 504 LYS n 
1 505 TYR n 
1 506 TYR n 
1 507 ILE n 
2 1   MET n 
2 2   ARG n 
2 3   ASN n 
2 4   LYS n 
2 5   ILE n 
2 6   PHE n 
2 7   ILE n 
2 8   SER n 
2 9   HIS n 
2 10  ALA n 
2 11  THR n 
2 12  PRO n 
2 13  GLU n 
2 14  ASP n 
2 15  ASP n 
2 16  ASP n 
2 17  PHE n 
2 18  THR n 
2 19  ARG n 
2 20  TRP n 
2 21  LEU n 
2 22  SER n 
2 23  LEU n 
2 24  LYS n 
2 25  LEU n 
2 26  ILE n 
2 27  GLY n 
2 28  LEU n 
2 29  GLY n 
2 30  TYR n 
2 31  GLU n 
2 32  VAL n 
2 33  TRP n 
2 34  CYS n 
2 35  ASP n 
2 36  ILE n 
2 37  LEU n 
2 38  PHE n 
2 39  LEU n 
2 40  ASP n 
2 41  LYS n 
2 42  GLY n 
2 43  VAL n 
2 44  ASP n 
2 45  PHE n 
2 46  TRP n 
2 47  SER n 
2 48  THR n 
2 49  ILE n 
2 50  GLU n 
2 51  LYS n 
2 52  GLU n 
2 53  ILE n 
2 54  ARG n 
2 55  GLU n 
2 56  ASN n 
2 57  THR n 
2 58  CYS n 
2 59  LYS n 
2 60  PHE n 
2 61  LEU n 
2 62  ILE n 
2 63  VAL n 
2 64  SER n 
2 65  SER n 
2 66  THR n 
2 67  ALA n 
2 68  GLY n 
2 69  ASN n 
2 70  LYS n 
2 71  ARG n 
2 72  GLU n 
2 73  GLY n 
2 74  VAL n 
2 75  LEU n 
2 76  LYS n 
2 77  GLU n 
2 78  LEU n 
2 79  ALA n 
2 80  VAL n 
2 81  ALA n 
2 82  THR n 
2 83  LYS n 
2 84  VAL n 
2 85  LYS n 
2 86  LYS n 
2 87  HIS n 
2 88  LEU n 
2 89  GLN n 
2 90  ASP n 
2 91  ASP n 
2 92  MET n 
2 93  PHE n 
2 94  ILE n 
2 95  ILE n 
2 96  PRO n 
2 97  LEU n 
2 98  ALA n 
2 99  ILE n 
2 100 ASP n 
2 101 GLU n 
2 102 ASN n 
2 103 LEU n 
2 104 SER n 
2 105 TYR n 
2 106 ASP n 
2 107 ASP n 
2 108 ILE n 
2 109 ASN n 
2 110 ILE n 
2 111 GLU n 
2 112 ILE n 
2 113 VAL n 
2 114 ARG n 
2 115 LEU n 
2 116 ASN n 
2 117 ALA n 
2 118 ILE n 
2 119 ASP n 
2 120 PHE n 
2 121 LYS n 
2 122 LYS n 
2 123 SER n 
2 124 TRP n 
2 125 ALA n 
2 126 LYS n 
2 127 GLY n 
2 128 LEU n 
2 129 GLN n 
2 130 ASP n 
2 131 LEU n 
2 132 LEU n 
2 133 ASP n 
2 134 ALA n 
2 135 PHE n 
2 136 GLU n 
2 137 LYS n 
2 138 GLN n 
2 139 ASN n 
2 140 VAL n 
2 141 PRO n 
2 142 LYS n 
2 143 LYS n 
2 144 PRO n 
2 145 PRO n 
2 146 ASP n 
2 147 HIS n 
2 148 SER n 
2 149 LYS n 
2 150 SER n 
2 151 ASN n 
2 152 LEU n 
2 153 LEU n 
2 154 TYR n 
2 155 GLN n 
2 156 GLN n 
2 157 ILE n 
2 158 PHE n 
2 159 LEU n 
2 160 HIS n 
2 161 ASP n 
2 162 LYS n 
2 163 GLN n 
2 164 ALA n 
2 165 ILE n 
2 166 GLU n 
2 167 LYS n 
2 168 GLU n 
2 169 GLU n 
2 170 THR n 
2 171 TYR n 
2 172 ASP n 
2 173 SER n 
2 174 ASN n 
2 175 TRP n 
2 176 PHE n 
2 177 PRO n 
2 178 ILE n 
2 179 ILE n 
2 180 SER n 
2 181 PHE n 
2 182 PRO n 
2 183 ASN n 
2 184 GLU n 
2 185 LEU n 
2 186 ARG n 
2 187 PHE n 
2 188 HIS n 
2 189 ARG n 
2 190 TYR n 
2 191 ASP n 
2 192 TRP n 
2 193 ARG n 
2 194 LEU n 
2 195 PRO n 
2 196 LYS n 
2 197 GLN n 
2 198 PHE n 
2 199 ASP n 
2 200 VAL n 
2 201 ARG n 
2 202 THR n 
2 203 LEU n 
2 204 ALA n 
2 205 PHE n 
2 206 PRO n 
2 207 ALA n 
2 208 ILE n 
2 209 ARG n 
2 210 TYR n 
2 211 LYS n 
2 212 GLU n 
2 213 TYR n 
2 214 LEU n 
2 215 CYS n 
2 216 THR n 
2 217 PHE n 
2 218 ALA n 
2 219 TRP n 
2 220 GLU n 
2 221 TYR n 
2 222 ASP n 
2 223 PHE n 
2 224 ILE n 
2 225 HIS n 
2 226 GLN n 
2 227 LEU n 
2 228 PRO n 
2 229 LYS n 
2 230 THR n 
2 231 GLU n 
2 232 THR n 
2 233 TYR n 
2 234 ASN n 
2 235 GLY n 
2 236 GLN n 
2 237 GLU n 
2 238 SER n 
2 239 ILE n 
2 240 ARG n 
2 241 ILE n 
2 242 SER n 
2 243 THR n 
2 244 SER n 
2 245 ASP n 
2 246 ILE n 
2 247 LEU n 
2 248 SER n 
2 249 GLY n 
2 250 ARG n 
2 251 TYR n 
2 252 ASP n 
2 253 THR n 
2 254 ASP n 
2 255 PHE n 
2 256 ILE n 
2 257 ARG n 
2 258 ASN n 
2 259 TYR n 
2 260 GLU n 
2 261 CYS n 
2 262 GLN n 
2 263 ARG n 
2 264 LEU n 
2 265 ILE n 
2 266 VAL n 
2 267 GLN n 
2 268 LEU n 
2 269 ILE n 
2 270 ASN n 
2 271 LYS n 
2 272 ALA n 
2 273 PHE n 
2 274 GLU n 
2 275 LEU n 
2 276 ARG n 
2 277 MET n 
2 278 LYS n 
2 279 ASP n 
2 280 LYS n 
2 281 ASN n 
2 282 VAL n 
2 283 ARG n 
2 284 GLU n 
2 285 TYR n 
2 286 GLN n 
2 287 MET n 
2 288 SER n 
2 289 LYS n 
2 290 THR n 
2 291 PHE n 
2 292 ALA n 
2 293 TYR n 
2 294 TRP n 
2 295 ILE n 
2 296 GLU n 
2 297 LYS n 
2 298 GLY n 
2 299 LYS n 
2 300 LEU n 
2 301 GLU n 
2 302 LYS n 
2 303 ASP n 
2 304 LYS n 
2 305 PHE n 
2 306 GLU n 
2 307 LYS n 
2 308 ILE n 
2 309 LYS n 
2 310 LEU n 
2 311 VAL n 
2 312 GLY n 
2 313 LYS n 
2 314 GLN n 
2 315 LYS n 
2 316 ASN n 
2 317 LYS n 
2 318 TYR n 
2 319 TRP n 
2 320 HIS n 
2 321 PHE n 
2 322 GLY n 
2 323 ILE n 
2 324 SER n 
2 325 ALA n 
2 326 ALA n 
2 327 GLY n 
2 328 LYS n 
2 329 LEU n 
2 330 TYR n 
2 331 PRO n 
2 332 SER n 
2 333 PRO n 
2 334 VAL n 
2 335 LEU n 
2 336 MET n 
2 337 VAL n 
2 338 SER n 
2 339 SER n 
2 340 HIS n 
2 341 ILE n 
2 342 ILE n 
2 343 PHE n 
2 344 THR n 
2 345 MET n 
2 346 ASP n 
2 347 GLY n 
2 348 ILE n 
2 349 ASN n 
2 350 LEU n 
2 351 ILE n 
2 352 LYS n 
2 353 SER n 
2 354 LYS n 
2 355 SER n 
2 356 ILE n 
2 357 GLN n 
2 358 HIS n 
2 359 SER n 
2 360 SER n 
2 361 ARG n 
2 362 ARG n 
2 363 LYS n 
2 364 GLN n 
2 365 GLY n 
2 366 LYS n 
2 367 ASN n 
2 368 TRP n 
2 369 TRP n 
2 370 ASN n 
2 371 ASP n 
2 372 LYS n 
2 373 TRP n 
2 374 ARG n 
2 375 GLU n 
2 376 LYS n 
2 377 LEU n 
2 378 LEU n 
2 379 ALA n 
2 380 PHE n 
2 381 ILE n 
2 382 ARG n 
2 383 PHE n 
2 384 LEU n 
2 385 SER n 
2 386 ASP n 
2 387 ASP n 
2 388 GLN n 
2 389 ASN n 
2 390 ALA n 
2 391 ILE n 
2 392 TYR n 
2 393 LEU n 
2 394 ASN n 
2 395 VAL n 
2 396 GLY n 
2 397 SER n 
2 398 GLU n 
2 399 GLU n 
2 400 LYS n 
2 401 ILE n 
2 402 LEU n 
2 403 ILE n 
2 404 SER n 
2 405 ASN n 
2 406 LYS n 
2 407 PRO n 
2 408 LEU n 
2 409 LYS n 
2 410 PHE n 
2 411 PHE n 
2 412 GLY n 
2 413 LYS n 
2 414 MET n 
2 415 SER n 
2 416 TYR n 
2 417 VAL n 
2 418 THR n 
2 419 PRO n 
2 420 SER n 
2 421 GLU n 
3 1   DT  n 
3 2   DG  n 
3 3   DA  n 
3 4   DG  n 
3 5   DG  n 
3 6   DT  n 
3 7   DA  n 
3 8   DG  n 
3 9   DT  n 
3 10  DA  n 
3 11  DG  n 
3 12  DG  n 
3 13  DT  n 
3 14  DT  n 
3 15  DG  n 
3 16  DT  n 
3 17  DA  n 
3 18  DT  n 
3 19  DA  n 
3 20  DG  n 
3 21  DT  n 
4 1   DT  n 
4 2   DA  n 
4 3   DT  n 
4 4   DA  n 
4 5   DC  n 
4 6   DA  n 
4 7   DA  n 
4 8   DC  n 
4 9   DC  n 
4 10  DT  n 
4 11  DA  n 
4 12  DC  n 
4 13  DT  n 
4 14  DA  n 
4 15  DC  n 
4 16  DC  n 
4 17  DT  n 
4 18  DC  n 
4 19  DA  n 
4 20  DT  n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 507 ? ? SAMN05660895_1671 ? ? ? ? ? ? 'Thermoflavifilum thermophilum' 1393122 ? ? ? ? ? ? ? ? 
'Escherichia coli BL21(DE3)' 469008 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 421 ? ? SAMN05660895_1670 ? ? ? ? ? ? 'Thermoflavifilum thermophilum' 1393122 ? ? ? ? ? ? ? ? 
'Escherichia coli BL21(DE3)' 469008 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_pdbx_entity_src_syn.entity_id 
_pdbx_entity_src_syn.pdbx_src_id 
_pdbx_entity_src_syn.pdbx_alt_source_flag 
_pdbx_entity_src_syn.pdbx_beg_seq_num 
_pdbx_entity_src_syn.pdbx_end_seq_num 
_pdbx_entity_src_syn.organism_scientific 
_pdbx_entity_src_syn.organism_common_name 
_pdbx_entity_src_syn.ncbi_taxonomy_id 
_pdbx_entity_src_syn.details 
3 1 sample 1 21 'Thermoflavifilum thermophilum' ? 1393122 ? 
4 1 sample 1 20 'Thermoflavifilum thermophilum' ? 1393122 ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                              ? 'C3 H7 N O2'      89.093  
ARG 'L-peptide linking' y ARGININE                             ? 'C6 H15 N4 O2 1'  175.209 
ASN 'L-peptide linking' y ASPARAGINE                           ? 'C4 H8 N2 O3'     132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                      ? 'C4 H7 N O4'      133.103 
CYS 'L-peptide linking' y CYSTEINE                             ? 'C3 H7 N O2 S'    121.158 
DA  'DNA linking'       y "2'-DEOXYADENOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O6 P' 331.222 
DC  'DNA linking'       y "2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE"  ? 'C9 H14 N3 O7 P'  307.197 
DG  'DNA linking'       y "2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O7 P' 347.221 
DT  'DNA linking'       y "THYMIDINE-5'-MONOPHOSPHATE"         ? 'C10 H15 N2 O8 P' 322.208 
GLN 'L-peptide linking' y GLUTAMINE                            ? 'C5 H10 N2 O3'    146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                      ? 'C5 H9 N O4'      147.129 
GLY 'peptide linking'   y GLYCINE                              ? 'C2 H5 N O2'      75.067  
HIS 'L-peptide linking' y HISTIDINE                            ? 'C6 H10 N3 O2 1'  156.162 
ILE 'L-peptide linking' y ISOLEUCINE                           ? 'C6 H13 N O2'     131.173 
LEU 'L-peptide linking' y LEUCINE                              ? 'C6 H13 N O2'     131.173 
LYS 'L-peptide linking' y LYSINE                               ? 'C6 H15 N2 O2 1'  147.195 
MET 'L-peptide linking' y METHIONINE                           ? 'C5 H11 N O2 S'   149.211 
MG  non-polymer         . 'MAGNESIUM ION'                      ? 'Mg 2'            24.305  
PHE 'L-peptide linking' y PHENYLALANINE                        ? 'C9 H11 N O2'     165.189 
PRO 'L-peptide linking' y PROLINE                              ? 'C5 H9 N O2'      115.130 
SER 'L-peptide linking' y SERINE                               ? 'C3 H7 N O3'      105.093 
THR 'L-peptide linking' y THREONINE                            ? 'C4 H9 N O3'      119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                           ? 'C11 H12 N2 O2'   204.225 
TYR 'L-peptide linking' y TYROSINE                             ? 'C9 H11 N O3'     181.189 
VAL 'L-peptide linking' y VALINE                               ? 'C5 H11 N O2'     117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   1   MET MET A . n 
A 1 2   LYS 2   2   2   LYS LYS A . n 
A 1 3   GLU 3   3   3   GLU GLU A . n 
A 1 4   LEU 4   4   4   LEU LEU A . n 
A 1 5   ILE 5   5   5   ILE ILE A . n 
A 1 6   TYR 6   6   6   TYR TYR A . n 
A 1 7   ILE 7   7   7   ILE ILE A . n 
A 1 8   GLU 8   8   8   GLU GLU A . n 
A 1 9   GLU 9   9   9   GLU GLU A . n 
A 1 10  PRO 10  10  10  PRO PRO A . n 
A 1 11  SER 11  11  11  SER SER A . n 
A 1 12  ILE 12  12  12  ILE ILE A . n 
A 1 13  LEU 13  13  13  LEU LEU A . n 
A 1 14  PHE 14  14  14  PHE PHE A . n 
A 1 15  ALA 15  15  15  ALA ALA A . n 
A 1 16  HIS 16  16  16  HIS HIS A . n 
A 1 17  GLY 17  17  17  GLY GLY A . n 
A 1 18  GLN 18  18  18  GLN GLN A . n 
A 1 19  LYS 19  19  19  LYS LYS A . n 
A 1 20  CYS 20  20  20  CYS CYS A . n 
A 1 21  THR 21  21  21  THR THR A . n 
A 1 22  ASP 22  22  22  ASP ASP A . n 
A 1 23  PRO 23  23  23  PRO PRO A . n 
A 1 24  ARG 24  24  24  ARG ARG A . n 
A 1 25  ASP 25  25  25  ASP ASP A . n 
A 1 26  GLY 26  26  26  GLY GLY A . n 
A 1 27  LEU 27  27  27  LEU LEU A . n 
A 1 28  ALA 28  28  28  ALA ALA A . n 
A 1 29  LEU 29  29  29  LEU LEU A . n 
A 1 30  PHE 30  30  30  PHE PHE A . n 
A 1 31  GLY 31  31  31  GLY GLY A . n 
A 1 32  PRO 32  32  32  PRO PRO A . n 
A 1 33  LEU 33  33  33  LEU LEU A . n 
A 1 34  ASN 34  34  34  ASN ASN A . n 
A 1 35  GLN 35  35  35  GLN GLN A . n 
A 1 36  ILE 36  36  36  ILE ILE A . n 
A 1 37  TYR 37  37  37  TYR TYR A . n 
A 1 38  GLY 38  38  38  GLY GLY A . n 
A 1 39  ILE 39  39  39  ILE ILE A . n 
A 1 40  LYS 40  40  40  LYS LYS A . n 
A 1 41  SER 41  41  41  SER SER A . n 
A 1 42  GLY 42  42  42  GLY GLY A . n 
A 1 43  VAL 43  43  43  VAL VAL A . n 
A 1 44  VAL 44  44  44  VAL VAL A . n 
A 1 45  GLY 45  45  45  GLY GLY A . n 
A 1 46  THR 46  46  46  THR THR A . n 
A 1 47  GLN 47  47  47  GLN GLN A . n 
A 1 48  LYS 48  48  48  LYS LYS A . n 
A 1 49  GLY 49  49  49  GLY GLY A . n 
A 1 50  LEU 50  50  50  LEU LEU A . n 
A 1 51  GLN 51  51  51  GLN GLN A . n 
A 1 52  ILE 52  52  52  ILE ILE A . n 
A 1 53  PHE 53  53  53  PHE PHE A . n 
A 1 54  LYS 54  54  54  LYS LYS A . n 
A 1 55  SER 55  55  55  SER SER A . n 
A 1 56  TYR 56  56  56  TYR TYR A . n 
A 1 57  LEU 57  57  57  LEU LEU A . n 
A 1 58  ASP 58  58  58  ASP ASP A . n 
A 1 59  LYS 59  59  59  LYS LYS A . n 
A 1 60  ILE 60  60  60  ILE ILE A . n 
A 1 61  GLN 61  61  61  GLN GLN A . n 
A 1 62  LYS 62  62  62  LYS LYS A . n 
A 1 63  PRO 63  63  63  PRO PRO A . n 
A 1 64  ILE 64  64  64  ILE ILE A . n 
A 1 65  TYR 65  65  65  TYR TYR A . n 
A 1 66  ASN 66  66  66  ASN ASN A . n 
A 1 67  HIS 67  67  67  HIS HIS A . n 
A 1 68  ASN 68  68  68  ASN ASN A . n 
A 1 69  ASN 69  69  69  ASN ASN A . n 
A 1 70  ILE 70  70  70  ILE ILE A . n 
A 1 71  THR 71  71  71  THR THR A . n 
A 1 72  ARG 72  72  72  ARG ARG A . n 
A 1 73  PRO 73  73  73  PRO PRO A . n 
A 1 74  MET 74  74  74  MET MET A . n 
A 1 75  PHE 75  75  75  PHE PHE A . n 
A 1 76  PRO 76  76  76  PRO PRO A . n 
A 1 77  GLY 77  77  77  GLY GLY A . n 
A 1 78  PHE 78  78  78  PHE PHE A . n 
A 1 79  GLU 79  79  79  GLU GLU A . n 
A 1 80  ALA 80  80  80  ALA ALA A . n 
A 1 81  VAL 81  81  81  VAL VAL A . n 
A 1 82  PHE 82  82  82  PHE PHE A . n 
A 1 83  GLY 83  83  83  GLY GLY A . n 
A 1 84  CYS 84  84  84  CYS CYS A . n 
A 1 85  LYS 85  85  85  LYS LYS A . n 
A 1 86  TRP 86  86  86  TRP TRP A . n 
A 1 87  GLU 87  87  87  GLU GLU A . n 
A 1 88  SER 88  88  88  SER SER A . n 
A 1 89  GLN 89  89  89  GLN GLN A . n 
A 1 90  ASN 90  90  90  ASN ASN A . n 
A 1 91  ILE 91  91  91  ILE ILE A . n 
A 1 92  VAL 92  92  92  VAL VAL A . n 
A 1 93  PHE 93  93  93  PHE PHE A . n 
A 1 94  LYS 94  94  94  LYS LYS A . n 
A 1 95  GLU 95  95  95  GLU GLU A . n 
A 1 96  ILE 96  96  96  ILE ILE A . n 
A 1 97  THR 97  97  97  THR THR A . n 
A 1 98  ASP 98  98  98  ASP ASP A . n 
A 1 99  GLU 99  99  99  GLU GLU A . n 
A 1 100 GLU 100 100 100 GLU GLU A . n 
A 1 101 ILE 101 101 101 ILE ILE A . n 
A 1 102 ARG 102 102 102 ARG ARG A . n 
A 1 103 ARG 103 103 103 ARG ARG A . n 
A 1 104 TYR 104 104 104 TYR TYR A . n 
A 1 105 LEU 105 105 105 LEU LEU A . n 
A 1 106 PHE 106 106 106 PHE PHE A . n 
A 1 107 ASN 107 107 107 ASN ASN A . n 
A 1 108 ALA 108 108 108 ALA ALA A . n 
A 1 109 SER 109 109 109 SER SER A . n 
A 1 110 THR 110 110 110 THR THR A . n 
A 1 111 HIS 111 111 111 HIS HIS A . n 
A 1 112 LYS 112 112 112 LYS LYS A . n 
A 1 113 ARG 113 113 113 ARG ARG A . n 
A 1 114 THR 114 114 114 THR THR A . n 
A 1 115 TYR 115 115 115 TYR TYR A . n 
A 1 116 ASP 116 116 116 ASP ASP A . n 
A 1 117 LEU 117 117 117 LEU LEU A . n 
A 1 118 VAL 118 118 118 VAL VAL A . n 
A 1 119 THR 119 119 119 THR THR A . n 
A 1 120 LEU 120 120 120 LEU LEU A . n 
A 1 121 PHE 121 121 121 PHE PHE A . n 
A 1 122 ASN 122 122 122 ASN ASN A . n 
A 1 123 ASP 123 123 123 ASP ASP A . n 
A 1 124 LYS 124 124 124 LYS LYS A . n 
A 1 125 ILE 125 125 125 ILE ILE A . n 
A 1 126 ILE 126 126 126 ILE ILE A . n 
A 1 127 THR 127 127 127 THR THR A . n 
A 1 128 ALA 128 128 128 ALA ALA A . n 
A 1 129 ASN 129 129 129 ASN ASN A . n 
A 1 130 LYS 130 130 130 LYS LYS A . n 
A 1 131 ASN 131 131 131 ASN ASN A . n 
A 1 132 ASP 132 132 132 ASP ASP A . n 
A 1 133 GLU 133 133 133 GLU GLU A . n 
A 1 134 GLU 134 134 134 GLU GLU A . n 
A 1 135 ARG 135 135 135 ARG ARG A . n 
A 1 136 VAL 136 136 136 VAL VAL A . n 
A 1 137 ASP 137 137 137 ASP ASP A . n 
A 1 138 VAL 138 138 138 VAL VAL A . n 
A 1 139 TRP 139 139 139 TRP TRP A . n 
A 1 140 PHE 140 140 140 PHE PHE A . n 
A 1 141 VAL 141 141 141 VAL VAL A . n 
A 1 142 ILE 142 142 142 ILE ILE A . n 
A 1 143 VAL 143 143 143 VAL VAL A . n 
A 1 144 PRO 144 144 144 PRO PRO A . n 
A 1 145 GLU 145 145 145 GLU GLU A . n 
A 1 146 GLU 146 146 146 GLU GLU A . n 
A 1 147 ILE 147 147 147 ILE ILE A . n 
A 1 148 TYR 148 148 148 TYR TYR A . n 
A 1 149 LYS 149 149 149 LYS LYS A . n 
A 1 150 TYR 150 150 150 TYR TYR A . n 
A 1 151 CYS 151 151 151 CYS CYS A . n 
A 1 152 ARG 152 152 152 ARG ARG A . n 
A 1 153 PRO 153 153 153 PRO PRO A . n 
A 1 154 ASN 154 154 154 ASN ASN A . n 
A 1 155 SER 155 155 155 SER SER A . n 
A 1 156 VAL 156 156 156 VAL VAL A . n 
A 1 157 LEU 157 157 157 LEU LEU A . n 
A 1 158 PRO 158 158 158 PRO PRO A . n 
A 1 159 ASN 159 159 159 ASN ASN A . n 
A 1 160 GLU 160 160 160 GLU GLU A . n 
A 1 161 LEU 161 161 161 LEU LEU A . n 
A 1 162 VAL 162 162 162 VAL VAL A . n 
A 1 163 GLN 163 163 163 GLN GLN A . n 
A 1 164 THR 164 164 164 THR THR A . n 
A 1 165 LYS 165 165 165 LYS LYS A . n 
A 1 166 SER 166 166 166 SER SER A . n 
A 1 167 LEU 167 167 167 LEU LEU A . n 
A 1 168 ILE 168 168 168 ILE ILE A . n 
A 1 169 SER 169 169 169 SER SER A . n 
A 1 170 LYS 170 170 ?   ?   ?   A . n 
A 1 171 SER 171 171 ?   ?   ?   A . n 
A 1 172 LYS 172 172 ?   ?   ?   A . n 
A 1 173 ALA 173 173 ?   ?   ?   A . n 
A 1 174 LYS 174 174 ?   ?   ?   A . n 
A 1 175 SER 175 175 ?   ?   ?   A . n 
A 1 176 PHE 176 176 ?   ?   ?   A . n 
A 1 177 ARG 177 177 ?   ?   ?   A . n 
A 1 178 TYR 178 178 ?   ?   ?   A . n 
A 1 179 THR 179 179 ?   ?   ?   A . n 
A 1 180 PRO 180 180 ?   ?   ?   A . n 
A 1 181 THR 181 181 ?   ?   ?   A . n 
A 1 182 LEU 182 182 ?   ?   ?   A . n 
A 1 183 PHE 183 183 ?   ?   ?   A . n 
A 1 184 GLU 184 184 ?   ?   ?   A . n 
A 1 185 GLU 185 185 ?   ?   ?   A . n 
A 1 186 PHE 186 186 ?   ?   ?   A . n 
A 1 187 ASN 187 187 ?   ?   ?   A . n 
A 1 188 LYS 188 188 ?   ?   ?   A . n 
A 1 189 LYS 189 189 ?   ?   ?   A . n 
A 1 190 LEU 190 190 ?   ?   ?   A . n 
A 1 191 LYS 191 191 ?   ?   ?   A . n 
A 1 192 GLU 192 192 ?   ?   ?   A . n 
A 1 193 VAL 193 193 ?   ?   ?   A . n 
A 1 194 GLU 194 194 ?   ?   ?   A . n 
A 1 195 LYS 195 195 ?   ?   ?   A . n 
A 1 196 GLU 196 196 ?   ?   ?   A . n 
A 1 197 ALA 197 197 ?   ?   ?   A . n 
A 1 198 LYS 198 198 ?   ?   ?   A . n 
A 1 199 THR 199 199 ?   ?   ?   A . n 
A 1 200 TYR 200 200 ?   ?   ?   A . n 
A 1 201 ASN 201 201 ?   ?   ?   A . n 
A 1 202 TYR 202 202 ?   ?   ?   A . n 
A 1 203 ASP 203 203 203 ASP ASP A . n 
A 1 204 ALA 204 204 204 ALA ALA A . n 
A 1 205 GLN 205 205 205 GLN GLN A . n 
A 1 206 PHE 206 206 206 PHE PHE A . n 
A 1 207 HIS 207 207 207 HIS HIS A . n 
A 1 208 ASP 208 208 208 ASP ASP A . n 
A 1 209 GLN 209 209 209 GLN GLN A . n 
A 1 210 LEU 210 210 210 LEU LEU A . n 
A 1 211 LYS 211 211 211 LYS LYS A . n 
A 1 212 ALA 212 212 212 ALA ALA A . n 
A 1 213 ARG 213 213 213 ARG ARG A . n 
A 1 214 LEU 214 214 214 LEU LEU A . n 
A 1 215 LEU 215 215 215 LEU LEU A . n 
A 1 216 GLU 216 216 216 GLU GLU A . n 
A 1 217 HIS 217 217 217 HIS HIS A . n 
A 1 218 THR 218 218 218 THR THR A . n 
A 1 219 ILE 219 219 219 ILE ILE A . n 
A 1 220 PRO 220 220 220 PRO PRO A . n 
A 1 221 THR 221 221 221 THR THR A . n 
A 1 222 GLN 222 222 222 GLN GLN A . n 
A 1 223 ILE 223 223 223 ILE ILE A . n 
A 1 224 LEU 224 224 224 LEU LEU A . n 
A 1 225 ARG 225 225 225 ARG ARG A . n 
A 1 226 GLU 226 226 226 GLU GLU A . n 
A 1 227 SER 227 227 227 SER SER A . n 
A 1 228 THR 228 228 228 THR THR A . n 
A 1 229 LEU 229 229 229 LEU LEU A . n 
A 1 230 ALA 230 230 230 ALA ALA A . n 
A 1 231 TRP 231 231 231 TRP TRP A . n 
A 1 232 ARG 232 232 232 ARG ARG A . n 
A 1 233 ASP 233 233 233 ASP ASP A . n 
A 1 234 PHE 234 234 234 PHE PHE A . n 
A 1 235 LYS 235 235 235 LYS LYS A . n 
A 1 236 ASN 236 236 236 ASN ASN A . n 
A 1 237 THR 237 237 237 THR THR A . n 
A 1 238 PHE 238 238 238 PHE PHE A . n 
A 1 239 GLY 239 239 239 GLY GLY A . n 
A 1 240 ALA 240 240 240 ALA ALA A . n 
A 1 241 PRO 241 241 241 PRO PRO A . n 
A 1 242 ILE 242 242 242 ILE ILE A . n 
A 1 243 ARG 243 243 243 ARG ARG A . n 
A 1 244 ASP 244 244 244 ASP ASP A . n 
A 1 245 PHE 245 245 245 PHE PHE A . n 
A 1 246 SER 246 246 246 SER SER A . n 
A 1 247 LYS 247 247 247 LYS LYS A . n 
A 1 248 ILE 248 248 248 ILE ILE A . n 
A 1 249 GLU 249 249 249 GLU GLU A . n 
A 1 250 GLY 250 250 250 GLY GLY A . n 
A 1 251 HIS 251 251 251 HIS HIS A . n 
A 1 252 LEU 252 252 252 LEU LEU A . n 
A 1 253 ALA 253 253 253 ALA ALA A . n 
A 1 254 TRP 254 254 254 TRP TRP A . n 
A 1 255 THR 255 255 255 THR THR A . n 
A 1 256 ILE 256 256 256 ILE ILE A . n 
A 1 257 SER 257 257 257 SER SER A . n 
A 1 258 THR 258 258 258 THR THR A . n 
A 1 259 ALA 259 259 259 ALA ALA A . n 
A 1 260 ALA 260 260 260 ALA ALA A . n 
A 1 261 TYR 261 261 261 TYR TYR A . n 
A 1 262 TYR 262 262 262 TYR TYR A . n 
A 1 263 LYS 263 263 263 LYS LYS A . n 
A 1 264 ALA 264 264 264 ALA ALA A . n 
A 1 265 GLY 265 265 265 GLY GLY A . n 
A 1 266 GLY 266 266 266 GLY GLY A . n 
A 1 267 LYS 267 267 267 LYS LYS A . n 
A 1 268 PRO 268 268 268 PRO PRO A . n 
A 1 269 TRP 269 269 269 TRP TRP A . n 
A 1 270 LYS 270 270 270 LYS LYS A . n 
A 1 271 LEU 271 271 271 LEU LEU A . n 
A 1 272 GLY 272 272 272 GLY GLY A . n 
A 1 273 ASP 273 273 273 ASP ASP A . n 
A 1 274 ILE 274 274 274 ILE ILE A . n 
A 1 275 ARG 275 275 275 ARG ARG A . n 
A 1 276 PRO 276 276 276 PRO PRO A . n 
A 1 277 GLY 277 277 277 GLY GLY A . n 
A 1 278 VAL 278 278 278 VAL VAL A . n 
A 1 279 CYS 279 279 279 CYS CYS A . n 
A 1 280 TYR 280 280 280 TYR TYR A . n 
A 1 281 LEU 281 281 281 LEU LEU A . n 
A 1 282 GLY 282 282 282 GLY GLY A . n 
A 1 283 LEU 283 283 283 LEU LEU A . n 
A 1 284 VAL 284 284 284 VAL VAL A . n 
A 1 285 TYR 285 285 285 TYR TYR A . n 
A 1 286 LYS 286 286 286 LYS LYS A . n 
A 1 287 LYS 287 287 287 LYS LYS A . n 
A 1 288 ILE 288 288 288 ILE ILE A . n 
A 1 289 GLU 289 289 289 GLU GLU A . n 
A 1 290 LYS 290 290 290 LYS LYS A . n 
A 1 291 SER 291 291 291 SER SER A . n 
A 1 292 LYS 292 292 292 LYS LYS A . n 
A 1 293 ASN 293 293 293 ASN ASN A . n 
A 1 294 PRO 294 294 294 PRO PRO A . n 
A 1 295 GLN 295 295 295 GLN GLN A . n 
A 1 296 ASN 296 296 296 ASN ASN A . n 
A 1 297 ALA 297 297 297 ALA ALA A . n 
A 1 298 CYS 298 298 298 CYS CYS A . n 
A 1 299 CYS 299 299 299 CYS CYS A . n 
A 1 300 ALA 300 300 300 ALA ALA A . n 
A 1 301 ALA 301 301 301 ALA ALA A . n 
A 1 302 GLN 302 302 302 GLN GLN A . n 
A 1 303 MET 303 303 303 MET MET A . n 
A 1 304 PHE 304 304 304 PHE PHE A . n 
A 1 305 LEU 305 305 305 LEU LEU A . n 
A 1 306 ASP 306 306 306 ASP ASP A . n 
A 1 307 ASN 307 307 307 ASN ASN A . n 
A 1 308 GLY 308 308 308 GLY GLY A . n 
A 1 309 ASP 309 309 309 ASP ASP A . n 
A 1 310 GLY 310 310 310 GLY GLY A . n 
A 1 311 THR 311 311 311 THR THR A . n 
A 1 312 VAL 312 312 312 VAL VAL A . n 
A 1 313 PHE 313 313 313 PHE PHE A . n 
A 1 314 LYS 314 314 314 LYS LYS A . n 
A 1 315 GLY 315 315 315 GLY GLY A . n 
A 1 316 GLU 316 316 316 GLU GLU A . n 
A 1 317 VAL 317 317 317 VAL VAL A . n 
A 1 318 GLY 318 318 318 GLY GLY A . n 
A 1 319 PRO 319 319 319 PRO PRO A . n 
A 1 320 TRP 320 320 320 TRP TRP A . n 
A 1 321 TYR 321 321 321 TYR TYR A . n 
A 1 322 ASN 322 322 322 ASN ASN A . n 
A 1 323 PRO 323 323 323 PRO PRO A . n 
A 1 324 GLU 324 324 324 GLU GLU A . n 
A 1 325 LYS 325 325 325 LYS LYS A . n 
A 1 326 GLY 326 326 326 GLY GLY A . n 
A 1 327 GLU 327 327 327 GLU GLU A . n 
A 1 328 TYR 328 328 328 TYR TYR A . n 
A 1 329 HIS 329 329 329 HIS HIS A . n 
A 1 330 LEU 330 330 330 LEU LEU A . n 
A 1 331 LYS 331 331 331 LYS LYS A . n 
A 1 332 PRO 332 332 332 PRO PRO A . n 
A 1 333 LYS 333 333 333 LYS LYS A . n 
A 1 334 GLU 334 334 334 GLU GLU A . n 
A 1 335 ALA 335 335 335 ALA ALA A . n 
A 1 336 LYS 336 336 336 LYS LYS A . n 
A 1 337 ALA 337 337 337 ALA ALA A . n 
A 1 338 LEU 338 338 338 LEU LEU A . n 
A 1 339 LEU 339 339 339 LEU LEU A . n 
A 1 340 THR 340 340 340 THR THR A . n 
A 1 341 GLN 341 341 341 GLN GLN A . n 
A 1 342 ALA 342 342 342 ALA ALA A . n 
A 1 343 LEU 343 343 343 LEU LEU A . n 
A 1 344 GLU 344 344 344 GLU GLU A . n 
A 1 345 SER 345 345 345 SER SER A . n 
A 1 346 TYR 346 346 346 TYR TYR A . n 
A 1 347 LYS 347 347 347 LYS LYS A . n 
A 1 348 GLU 348 348 348 GLU GLU A . n 
A 1 349 GLN 349 349 349 GLN GLN A . n 
A 1 350 ASN 350 350 350 ASN ASN A . n 
A 1 351 LYS 351 351 351 LYS LYS A . n 
A 1 352 SER 352 352 352 SER SER A . n 
A 1 353 TYR 353 353 353 TYR TYR A . n 
A 1 354 PRO 354 354 354 PRO PRO A . n 
A 1 355 LYS 355 355 355 LYS LYS A . n 
A 1 356 GLU 356 356 356 GLU GLU A . n 
A 1 357 VAL 357 357 357 VAL VAL A . n 
A 1 358 PHE 358 358 358 PHE PHE A . n 
A 1 359 ILE 359 359 359 ILE ILE A . n 
A 1 360 HIS 360 360 360 HIS HIS A . n 
A 1 361 ALA 361 361 361 ALA ALA A . n 
A 1 362 ARG 362 362 362 ARG ARG A . n 
A 1 363 THR 363 363 363 THR THR A . n 
A 1 364 ARG 364 364 364 ARG ARG A . n 
A 1 365 PHE 365 365 365 PHE PHE A . n 
A 1 366 ASN 366 366 366 ASN ASN A . n 
A 1 367 ASP 367 367 367 ASP ASP A . n 
A 1 368 GLU 368 368 368 GLU GLU A . n 
A 1 369 GLU 369 369 369 GLU GLU A . n 
A 1 370 TRP 370 370 370 TRP TRP A . n 
A 1 371 ASN 371 371 371 ASN ASN A . n 
A 1 372 ALA 372 372 372 ALA ALA A . n 
A 1 373 PHE 373 373 373 PHE PHE A . n 
A 1 374 ASN 374 374 374 ASN ASN A . n 
A 1 375 GLU 375 375 375 GLU GLU A . n 
A 1 376 VAL 376 376 376 VAL VAL A . n 
A 1 377 THR 377 377 377 THR THR A . n 
A 1 378 PRO 378 378 378 PRO PRO A . n 
A 1 379 LYS 379 379 379 LYS LYS A . n 
A 1 380 ASN 380 380 380 ASN ASN A . n 
A 1 381 THR 381 381 381 THR THR A . n 
A 1 382 ASN 382 382 382 ASN ASN A . n 
A 1 383 LEU 383 383 383 LEU LEU A . n 
A 1 384 VAL 384 384 384 VAL VAL A . n 
A 1 385 GLY 385 385 385 GLY GLY A . n 
A 1 386 VAL 386 386 386 VAL VAL A . n 
A 1 387 THR 387 387 387 THR THR A . n 
A 1 388 ILE 388 388 388 ILE ILE A . n 
A 1 389 THR 389 389 389 THR THR A . n 
A 1 390 LYS 390 390 390 LYS LYS A . n 
A 1 391 SER 391 391 391 SER SER A . n 
A 1 392 LYS 392 392 392 LYS LYS A . n 
A 1 393 PRO 393 393 393 PRO PRO A . n 
A 1 394 LEU 394 394 394 LEU LEU A . n 
A 1 395 LYS 395 395 395 LYS LYS A . n 
A 1 396 LEU 396 396 396 LEU LEU A . n 
A 1 397 TYR 397 397 397 TYR TYR A . n 
A 1 398 LYS 398 398 398 LYS LYS A . n 
A 1 399 THR 399 399 399 THR THR A . n 
A 1 400 GLU 400 400 400 GLU GLU A . n 
A 1 401 GLY 401 401 401 GLY GLY A . n 
A 1 402 ALA 402 402 402 ALA ALA A . n 
A 1 403 PHE 403 403 403 PHE PHE A . n 
A 1 404 PRO 404 404 404 PRO PRO A . n 
A 1 405 ILE 405 405 405 ILE ILE A . n 
A 1 406 MET 406 406 406 MET MET A . n 
A 1 407 ARG 407 407 407 ARG ARG A . n 
A 1 408 GLY 408 408 408 GLY GLY A . n 
A 1 409 ASN 409 409 409 ASN ASN A . n 
A 1 410 ALA 410 410 410 ALA ALA A . n 
A 1 411 TYR 411 411 411 TYR TYR A . n 
A 1 412 ILE 412 412 412 ILE ILE A . n 
A 1 413 VAL 413 413 413 VAL VAL A . n 
A 1 414 ASP 414 414 414 ASP ASP A . n 
A 1 415 GLU 415 415 415 GLU GLU A . n 
A 1 416 LYS 416 416 416 LYS LYS A . n 
A 1 417 LYS 417 417 417 LYS LYS A . n 
A 1 418 ALA 418 418 418 ALA ALA A . n 
A 1 419 PHE 419 419 419 PHE PHE A . n 
A 1 420 LEU 420 420 420 LEU LEU A . n 
A 1 421 TRP 421 421 421 TRP TRP A . n 
A 1 422 THR 422 422 422 THR THR A . n 
A 1 423 LEU 423 423 423 LEU LEU A . n 
A 1 424 GLY 424 424 424 GLY GLY A . n 
A 1 425 PHE 425 425 425 PHE PHE A . n 
A 1 426 VAL 426 426 426 VAL VAL A . n 
A 1 427 PRO 427 427 427 PRO PRO A . n 
A 1 428 LYS 428 428 428 LYS LYS A . n 
A 1 429 LEU 429 429 429 LEU LEU A . n 
A 1 430 GLN 430 430 430 GLN GLN A . n 
A 1 431 SER 431 431 431 SER SER A . n 
A 1 432 THR 432 432 432 THR THR A . n 
A 1 433 LEU 433 433 433 LEU LEU A . n 
A 1 434 SER 434 434 434 SER SER A . n 
A 1 435 MET 435 435 435 MET MET A . n 
A 1 436 GLU 436 436 436 GLU GLU A . n 
A 1 437 VAL 437 437 437 VAL VAL A . n 
A 1 438 PRO 438 438 438 PRO PRO A . n 
A 1 439 ASN 439 439 439 ASN ASN A . n 
A 1 440 PRO 440 440 440 PRO PRO A . n 
A 1 441 ILE 441 441 441 ILE ILE A . n 
A 1 442 PHE 442 442 442 PHE PHE A . n 
A 1 443 ILE 443 443 443 ILE ILE A . n 
A 1 444 GLU 444 444 444 GLU GLU A . n 
A 1 445 ILE 445 445 445 ILE ILE A . n 
A 1 446 ASN 446 446 446 ASN ASN A . n 
A 1 447 LYS 447 447 447 LYS LYS A . n 
A 1 448 GLY 448 448 448 GLY GLY A . n 
A 1 449 GLU 449 449 449 GLU GLU A . n 
A 1 450 ALA 450 450 450 ALA ALA A . n 
A 1 451 GLU 451 451 451 GLU GLU A . n 
A 1 452 ILE 452 452 452 ILE ILE A . n 
A 1 453 GLN 453 453 453 GLN GLN A . n 
A 1 454 GLN 454 454 454 GLN GLN A . n 
A 1 455 VAL 455 455 455 VAL VAL A . n 
A 1 456 LEU 456 456 456 LEU LEU A . n 
A 1 457 LYS 457 457 457 LYS LYS A . n 
A 1 458 ASP 458 458 458 ASP ASP A . n 
A 1 459 ILE 459 459 459 ILE ILE A . n 
A 1 460 LEU 460 460 460 LEU LEU A . n 
A 1 461 ALA 461 461 461 ALA ALA A . n 
A 1 462 LEU 462 462 462 LEU LEU A . n 
A 1 463 THR 463 463 463 THR THR A . n 
A 1 464 LYS 464 464 464 LYS LYS A . n 
A 1 465 LEU 465 465 465 LEU LEU A . n 
A 1 466 ASN 466 466 466 ASN ASN A . n 
A 1 467 TYR 467 467 467 TYR TYR A . n 
A 1 468 ASN 468 468 468 ASN ASN A . n 
A 1 469 ALA 469 469 469 ALA ALA A . n 
A 1 470 CYS 470 470 470 CYS CYS A . n 
A 1 471 ILE 471 471 471 ILE ILE A . n 
A 1 472 TYR 472 472 472 TYR TYR A . n 
A 1 473 ALA 473 473 473 ALA ALA A . n 
A 1 474 ASP 474 474 474 ASP ASP A . n 
A 1 475 GLY 475 475 475 GLY GLY A . n 
A 1 476 GLU 476 476 476 GLU GLU A . n 
A 1 477 PRO 477 477 477 PRO PRO A . n 
A 1 478 VAL 478 478 478 VAL VAL A . n 
A 1 479 THR 479 479 479 THR THR A . n 
A 1 480 LEU 480 480 480 LEU LEU A . n 
A 1 481 ARG 481 481 481 ARG ARG A . n 
A 1 482 PHE 482 482 482 PHE PHE A . n 
A 1 483 ALA 483 483 483 ALA ALA A . n 
A 1 484 ASN 484 484 484 ASN ASN A . n 
A 1 485 LYS 485 485 485 LYS LYS A . n 
A 1 486 ILE 486 486 486 ILE ILE A . n 
A 1 487 GLY 487 487 487 GLY GLY A . n 
A 1 488 GLU 488 488 488 GLU GLU A . n 
A 1 489 ILE 489 489 489 ILE ILE A . n 
A 1 490 LEU 490 490 490 LEU LEU A . n 
A 1 491 THR 491 491 491 THR THR A . n 
A 1 492 ALA 492 492 492 ALA ALA A . n 
A 1 493 SER 493 493 493 SER SER A . n 
A 1 494 THR 494 494 494 THR THR A . n 
A 1 495 GLU 495 495 495 GLU GLU A . n 
A 1 496 ILE 496 496 496 ILE ILE A . n 
A 1 497 LYS 497 497 497 LYS LYS A . n 
A 1 498 THR 498 498 498 THR THR A . n 
A 1 499 PRO 499 499 499 PRO PRO A . n 
A 1 500 PRO 500 500 500 PRO PRO A . n 
A 1 501 LEU 501 501 501 LEU LEU A . n 
A 1 502 ALA 502 502 502 ALA ALA A . n 
A 1 503 PHE 503 503 503 PHE PHE A . n 
A 1 504 LYS 504 504 504 LYS LYS A . n 
A 1 505 TYR 505 505 505 TYR TYR A . n 
A 1 506 TYR 506 506 506 TYR TYR A . n 
A 1 507 ILE 507 507 507 ILE ILE A . n 
B 2 1   MET 1   1   1   MET MET B . n 
B 2 2   ARG 2   2   2   ARG ARG B . n 
B 2 3   ASN 3   3   3   ASN ASN B . n 
B 2 4   LYS 4   4   4   LYS LYS B . n 
B 2 5   ILE 5   5   5   ILE ILE B . n 
B 2 6   PHE 6   6   6   PHE PHE B . n 
B 2 7   ILE 7   7   7   ILE ILE B . n 
B 2 8   SER 8   8   8   SER SER B . n 
B 2 9   HIS 9   9   9   HIS HIS B . n 
B 2 10  ALA 10  10  10  ALA ALA B . n 
B 2 11  THR 11  11  11  THR THR B . n 
B 2 12  PRO 12  12  12  PRO PRO B . n 
B 2 13  GLU 13  13  13  GLU GLU B . n 
B 2 14  ASP 14  14  14  ASP ASP B . n 
B 2 15  ASP 15  15  15  ASP ASP B . n 
B 2 16  ASP 16  16  16  ASP ASP B . n 
B 2 17  PHE 17  17  17  PHE PHE B . n 
B 2 18  THR 18  18  18  THR THR B . n 
B 2 19  ARG 19  19  19  ARG ARG B . n 
B 2 20  TRP 20  20  20  TRP TRP B . n 
B 2 21  LEU 21  21  21  LEU LEU B . n 
B 2 22  SER 22  22  22  SER SER B . n 
B 2 23  LEU 23  23  23  LEU LEU B . n 
B 2 24  LYS 24  24  24  LYS LYS B . n 
B 2 25  LEU 25  25  25  LEU LEU B . n 
B 2 26  ILE 26  26  26  ILE ILE B . n 
B 2 27  GLY 27  27  27  GLY GLY B . n 
B 2 28  LEU 28  28  28  LEU LEU B . n 
B 2 29  GLY 29  29  29  GLY GLY B . n 
B 2 30  TYR 30  30  30  TYR TYR B . n 
B 2 31  GLU 31  31  31  GLU GLU B . n 
B 2 32  VAL 32  32  32  VAL VAL B . n 
B 2 33  TRP 33  33  33  TRP TRP B . n 
B 2 34  CYS 34  34  34  CYS CYS B . n 
B 2 35  ASP 35  35  35  ASP ASP B . n 
B 2 36  ILE 36  36  36  ILE ILE B . n 
B 2 37  LEU 37  37  37  LEU LEU B . n 
B 2 38  PHE 38  38  38  PHE PHE B . n 
B 2 39  LEU 39  39  39  LEU LEU B . n 
B 2 40  ASP 40  40  40  ASP ASP B . n 
B 2 41  LYS 41  41  41  LYS LYS B . n 
B 2 42  GLY 42  42  42  GLY GLY B . n 
B 2 43  VAL 43  43  43  VAL VAL B . n 
B 2 44  ASP 44  44  44  ASP ASP B . n 
B 2 45  PHE 45  45  45  PHE PHE B . n 
B 2 46  TRP 46  46  46  TRP TRP B . n 
B 2 47  SER 47  47  47  SER SER B . n 
B 2 48  THR 48  48  48  THR THR B . n 
B 2 49  ILE 49  49  49  ILE ILE B . n 
B 2 50  GLU 50  50  50  GLU GLU B . n 
B 2 51  LYS 51  51  51  LYS LYS B . n 
B 2 52  GLU 52  52  52  GLU GLU B . n 
B 2 53  ILE 53  53  53  ILE ILE B . n 
B 2 54  ARG 54  54  54  ARG ARG B . n 
B 2 55  GLU 55  55  55  GLU GLU B . n 
B 2 56  ASN 56  56  56  ASN ASN B . n 
B 2 57  THR 57  57  57  THR THR B . n 
B 2 58  CYS 58  58  58  CYS CYS B . n 
B 2 59  LYS 59  59  59  LYS LYS B . n 
B 2 60  PHE 60  60  60  PHE PHE B . n 
B 2 61  LEU 61  61  61  LEU LEU B . n 
B 2 62  ILE 62  62  62  ILE ILE B . n 
B 2 63  VAL 63  63  63  VAL VAL B . n 
B 2 64  SER 64  64  64  SER SER B . n 
B 2 65  SER 65  65  65  SER SER B . n 
B 2 66  THR 66  66  66  THR THR B . n 
B 2 67  ALA 67  67  67  ALA ALA B . n 
B 2 68  GLY 68  68  68  GLY GLY B . n 
B 2 69  ASN 69  69  69  ASN ASN B . n 
B 2 70  LYS 70  70  70  LYS LYS B . n 
B 2 71  ARG 71  71  71  ARG ARG B . n 
B 2 72  GLU 72  72  72  GLU GLU B . n 
B 2 73  GLY 73  73  73  GLY GLY B . n 
B 2 74  VAL 74  74  74  VAL VAL B . n 
B 2 75  LEU 75  75  75  LEU LEU B . n 
B 2 76  LYS 76  76  76  LYS LYS B . n 
B 2 77  GLU 77  77  77  GLU GLU B . n 
B 2 78  LEU 78  78  78  LEU LEU B . n 
B 2 79  ALA 79  79  79  ALA ALA B . n 
B 2 80  VAL 80  80  80  VAL VAL B . n 
B 2 81  ALA 81  81  81  ALA ALA B . n 
B 2 82  THR 82  82  82  THR THR B . n 
B 2 83  LYS 83  83  83  LYS LYS B . n 
B 2 84  VAL 84  84  84  VAL VAL B . n 
B 2 85  LYS 85  85  85  LYS LYS B . n 
B 2 86  LYS 86  86  86  LYS LYS B . n 
B 2 87  HIS 87  87  87  HIS HIS B . n 
B 2 88  LEU 88  88  88  LEU LEU B . n 
B 2 89  GLN 89  89  89  GLN GLN B . n 
B 2 90  ASP 90  90  90  ASP ASP B . n 
B 2 91  ASP 91  91  91  ASP ASP B . n 
B 2 92  MET 92  92  92  MET MET B . n 
B 2 93  PHE 93  93  93  PHE PHE B . n 
B 2 94  ILE 94  94  94  ILE ILE B . n 
B 2 95  ILE 95  95  95  ILE ILE B . n 
B 2 96  PRO 96  96  96  PRO PRO B . n 
B 2 97  LEU 97  97  97  LEU LEU B . n 
B 2 98  ALA 98  98  98  ALA ALA B . n 
B 2 99  ILE 99  99  99  ILE ILE B . n 
B 2 100 ASP 100 100 100 ASP ASP B . n 
B 2 101 GLU 101 101 101 GLU GLU B . n 
B 2 102 ASN 102 102 102 ASN ASN B . n 
B 2 103 LEU 103 103 103 LEU LEU B . n 
B 2 104 SER 104 104 104 SER SER B . n 
B 2 105 TYR 105 105 105 TYR TYR B . n 
B 2 106 ASP 106 106 106 ASP ASP B . n 
B 2 107 ASP 107 107 107 ASP ASP B . n 
B 2 108 ILE 108 108 108 ILE ILE B . n 
B 2 109 ASN 109 109 109 ASN ASN B . n 
B 2 110 ILE 110 110 110 ILE ILE B . n 
B 2 111 GLU 111 111 111 GLU GLU B . n 
B 2 112 ILE 112 112 112 ILE ILE B . n 
B 2 113 VAL 113 113 113 VAL VAL B . n 
B 2 114 ARG 114 114 114 ARG ARG B . n 
B 2 115 LEU 115 115 115 LEU LEU B . n 
B 2 116 ASN 116 116 116 ASN ASN B . n 
B 2 117 ALA 117 117 117 ALA ALA B . n 
B 2 118 ILE 118 118 118 ILE ILE B . n 
B 2 119 ASP 119 119 119 ASP ASP B . n 
B 2 120 PHE 120 120 120 PHE PHE B . n 
B 2 121 LYS 121 121 121 LYS LYS B . n 
B 2 122 LYS 122 122 122 LYS LYS B . n 
B 2 123 SER 123 123 123 SER SER B . n 
B 2 124 TRP 124 124 124 TRP TRP B . n 
B 2 125 ALA 125 125 125 ALA ALA B . n 
B 2 126 LYS 126 126 126 LYS LYS B . n 
B 2 127 GLY 127 127 127 GLY GLY B . n 
B 2 128 LEU 128 128 128 LEU LEU B . n 
B 2 129 GLN 129 129 129 GLN GLN B . n 
B 2 130 ASP 130 130 130 ASP ASP B . n 
B 2 131 LEU 131 131 131 LEU LEU B . n 
B 2 132 LEU 132 132 132 LEU LEU B . n 
B 2 133 ASP 133 133 133 ASP ASP B . n 
B 2 134 ALA 134 134 134 ALA ALA B . n 
B 2 135 PHE 135 135 135 PHE PHE B . n 
B 2 136 GLU 136 136 136 GLU GLU B . n 
B 2 137 LYS 137 137 137 LYS LYS B . n 
B 2 138 GLN 138 138 138 GLN GLN B . n 
B 2 139 ASN 139 139 139 ASN ASN B . n 
B 2 140 VAL 140 140 140 VAL VAL B . n 
B 2 141 PRO 141 141 141 PRO PRO B . n 
B 2 142 LYS 142 142 142 LYS LYS B . n 
B 2 143 LYS 143 143 143 LYS LYS B . n 
B 2 144 PRO 144 144 144 PRO PRO B . n 
B 2 145 PRO 145 145 145 PRO PRO B . n 
B 2 146 ASP 146 146 146 ASP ASP B . n 
B 2 147 HIS 147 147 147 HIS HIS B . n 
B 2 148 SER 148 148 148 SER SER B . n 
B 2 149 LYS 149 149 149 LYS LYS B . n 
B 2 150 SER 150 150 150 SER SER B . n 
B 2 151 ASN 151 151 151 ASN ASN B . n 
B 2 152 LEU 152 152 152 LEU LEU B . n 
B 2 153 LEU 153 153 153 LEU LEU B . n 
B 2 154 TYR 154 154 154 TYR TYR B . n 
B 2 155 GLN 155 155 155 GLN GLN B . n 
B 2 156 GLN 156 156 156 GLN GLN B . n 
B 2 157 ILE 157 157 157 ILE ILE B . n 
B 2 158 PHE 158 158 158 PHE PHE B . n 
B 2 159 LEU 159 159 159 LEU LEU B . n 
B 2 160 HIS 160 160 160 HIS HIS B . n 
B 2 161 ASP 161 161 161 ASP ASP B . n 
B 2 162 LYS 162 162 162 LYS LYS B . n 
B 2 163 GLN 163 163 163 GLN GLN B . n 
B 2 164 ALA 164 164 164 ALA ALA B . n 
B 2 165 ILE 165 165 165 ILE ALA B . n 
B 2 166 GLU 166 166 166 GLU ALA B . n 
B 2 167 LYS 167 167 167 LYS ALA B . n 
B 2 168 GLU 168 168 168 GLU ALA B . n 
B 2 169 GLU 169 169 169 GLU GLU B . n 
B 2 170 THR 170 170 170 THR THR B . n 
B 2 171 TYR 171 171 171 TYR TYR B . n 
B 2 172 ASP 172 172 172 ASP ASP B . n 
B 2 173 SER 173 173 173 SER SER B . n 
B 2 174 ASN 174 174 174 ASN ASN B . n 
B 2 175 TRP 175 175 175 TRP TRP B . n 
B 2 176 PHE 176 176 176 PHE PHE B . n 
B 2 177 PRO 177 177 177 PRO PRO B . n 
B 2 178 ILE 178 178 178 ILE ILE B . n 
B 2 179 ILE 179 179 179 ILE ILE B . n 
B 2 180 SER 180 180 180 SER SER B . n 
B 2 181 PHE 181 181 181 PHE PHE B . n 
B 2 182 PRO 182 182 182 PRO PRO B . n 
B 2 183 ASN 183 183 183 ASN ASN B . n 
B 2 184 GLU 184 184 184 GLU GLU B . n 
B 2 185 LEU 185 185 185 LEU LEU B . n 
B 2 186 ARG 186 186 186 ARG ARG B . n 
B 2 187 PHE 187 187 187 PHE PHE B . n 
B 2 188 HIS 188 188 188 HIS HIS B . n 
B 2 189 ARG 189 189 189 ARG ARG B . n 
B 2 190 TYR 190 190 190 TYR TYR B . n 
B 2 191 ASP 191 191 191 ASP ASP B . n 
B 2 192 TRP 192 192 192 TRP TRP B . n 
B 2 193 ARG 193 193 193 ARG ARG B . n 
B 2 194 LEU 194 194 194 LEU LEU B . n 
B 2 195 PRO 195 195 195 PRO PRO B . n 
B 2 196 LYS 196 196 196 LYS LYS B . n 
B 2 197 GLN 197 197 197 GLN GLN B . n 
B 2 198 PHE 198 198 198 PHE PHE B . n 
B 2 199 ASP 199 199 199 ASP ASP B . n 
B 2 200 VAL 200 200 200 VAL VAL B . n 
B 2 201 ARG 201 201 201 ARG ARG B . n 
B 2 202 THR 202 202 202 THR THR B . n 
B 2 203 LEU 203 203 203 LEU LEU B . n 
B 2 204 ALA 204 204 204 ALA ALA B . n 
B 2 205 PHE 205 205 205 PHE PHE B . n 
B 2 206 PRO 206 206 206 PRO PRO B . n 
B 2 207 ALA 207 207 207 ALA ALA B . n 
B 2 208 ILE 208 208 208 ILE ILE B . n 
B 2 209 ARG 209 209 209 ARG ARG B . n 
B 2 210 TYR 210 210 210 TYR TYR B . n 
B 2 211 LYS 211 211 211 LYS LYS B . n 
B 2 212 GLU 212 212 212 GLU GLU B . n 
B 2 213 TYR 213 213 213 TYR TYR B . n 
B 2 214 LEU 214 214 214 LEU LEU B . n 
B 2 215 CYS 215 215 215 CYS CYS B . n 
B 2 216 THR 216 216 216 THR THR B . n 
B 2 217 PHE 217 217 217 PHE PHE B . n 
B 2 218 ALA 218 218 218 ALA ALA B . n 
B 2 219 TRP 219 219 219 TRP TRP B . n 
B 2 220 GLU 220 220 220 GLU GLU B . n 
B 2 221 TYR 221 221 221 TYR TYR B . n 
B 2 222 ASP 222 222 222 ASP ASP B . n 
B 2 223 PHE 223 223 223 PHE PHE B . n 
B 2 224 ILE 224 224 224 ILE ILE B . n 
B 2 225 HIS 225 225 225 HIS HIS B . n 
B 2 226 GLN 226 226 226 GLN GLN B . n 
B 2 227 LEU 227 227 227 LEU LEU B . n 
B 2 228 PRO 228 228 228 PRO PRO B . n 
B 2 229 LYS 229 229 229 LYS LYS B . n 
B 2 230 THR 230 230 230 THR THR B . n 
B 2 231 GLU 231 231 231 GLU GLU B . n 
B 2 232 THR 232 232 232 THR THR B . n 
B 2 233 TYR 233 233 233 TYR TYR B . n 
B 2 234 ASN 234 234 234 ASN ASN B . n 
B 2 235 GLY 235 235 235 GLY GLY B . n 
B 2 236 GLN 236 236 236 GLN GLN B . n 
B 2 237 GLU 237 237 237 GLU GLU B . n 
B 2 238 SER 238 238 238 SER SER B . n 
B 2 239 ILE 239 239 239 ILE ILE B . n 
B 2 240 ARG 240 240 240 ARG ARG B . n 
B 2 241 ILE 241 241 241 ILE ILE B . n 
B 2 242 SER 242 242 242 SER SER B . n 
B 2 243 THR 243 243 243 THR THR B . n 
B 2 244 SER 244 244 244 SER SER B . n 
B 2 245 ASP 245 245 245 ASP ASP B . n 
B 2 246 ILE 246 246 246 ILE ILE B . n 
B 2 247 LEU 247 247 247 LEU LEU B . n 
B 2 248 SER 248 248 248 SER SER B . n 
B 2 249 GLY 249 249 249 GLY GLY B . n 
B 2 250 ARG 250 250 250 ARG ARG B . n 
B 2 251 TYR 251 251 251 TYR TYR B . n 
B 2 252 ASP 252 252 252 ASP ASP B . n 
B 2 253 THR 253 253 253 THR THR B . n 
B 2 254 ASP 254 254 254 ASP ASP B . n 
B 2 255 PHE 255 255 255 PHE PHE B . n 
B 2 256 ILE 256 256 256 ILE ILE B . n 
B 2 257 ARG 257 257 257 ARG ARG B . n 
B 2 258 ASN 258 258 258 ASN ASN B . n 
B 2 259 TYR 259 259 259 TYR TYR B . n 
B 2 260 GLU 260 260 260 GLU GLU B . n 
B 2 261 CYS 261 261 261 CYS CYS B . n 
B 2 262 GLN 262 262 262 GLN GLN B . n 
B 2 263 ARG 263 263 263 ARG ARG B . n 
B 2 264 LEU 264 264 264 LEU LEU B . n 
B 2 265 ILE 265 265 265 ILE ILE B . n 
B 2 266 VAL 266 266 266 VAL VAL B . n 
B 2 267 GLN 267 267 267 GLN GLN B . n 
B 2 268 LEU 268 268 268 LEU LEU B . n 
B 2 269 ILE 269 269 269 ILE ILE B . n 
B 2 270 ASN 270 270 270 ASN ASN B . n 
B 2 271 LYS 271 271 271 LYS LYS B . n 
B 2 272 ALA 272 272 272 ALA ALA B . n 
B 2 273 PHE 273 273 273 PHE PHE B . n 
B 2 274 GLU 274 274 274 GLU GLU B . n 
B 2 275 LEU 275 275 275 LEU LEU B . n 
B 2 276 ARG 276 276 276 ARG ARG B . n 
B 2 277 MET 277 277 277 MET MET B . n 
B 2 278 LYS 278 278 278 LYS LYS B . n 
B 2 279 ASP 279 279 279 ASP ASP B . n 
B 2 280 LYS 280 280 280 LYS LYS B . n 
B 2 281 ASN 281 281 281 ASN ASN B . n 
B 2 282 VAL 282 282 282 VAL VAL B . n 
B 2 283 ARG 283 283 283 ARG ARG B . n 
B 2 284 GLU 284 284 284 GLU GLU B . n 
B 2 285 TYR 285 285 285 TYR TYR B . n 
B 2 286 GLN 286 286 286 GLN GLN B . n 
B 2 287 MET 287 287 287 MET MET B . n 
B 2 288 SER 288 288 288 SER SER B . n 
B 2 289 LYS 289 289 289 LYS LYS B . n 
B 2 290 THR 290 290 290 THR THR B . n 
B 2 291 PHE 291 291 291 PHE PHE B . n 
B 2 292 ALA 292 292 292 ALA ALA B . n 
B 2 293 TYR 293 293 293 TYR TYR B . n 
B 2 294 TRP 294 294 294 TRP TRP B . n 
B 2 295 ILE 295 295 295 ILE ILE B . n 
B 2 296 GLU 296 296 296 GLU GLU B . n 
B 2 297 LYS 297 297 297 LYS LYS B . n 
B 2 298 GLY 298 298 298 GLY GLY B . n 
B 2 299 LYS 299 299 299 LYS LYS B . n 
B 2 300 LEU 300 300 300 LEU LEU B . n 
B 2 301 GLU 301 301 301 GLU GLU B . n 
B 2 302 LYS 302 302 302 LYS LYS B . n 
B 2 303 ASP 303 303 303 ASP ASP B . n 
B 2 304 LYS 304 304 304 LYS LYS B . n 
B 2 305 PHE 305 305 305 PHE PHE B . n 
B 2 306 GLU 306 306 306 GLU GLU B . n 
B 2 307 LYS 307 307 307 LYS LYS B . n 
B 2 308 ILE 308 308 308 ILE ILE B . n 
B 2 309 LYS 309 309 309 LYS LYS B . n 
B 2 310 LEU 310 310 310 LEU LEU B . n 
B 2 311 VAL 311 311 311 VAL VAL B . n 
B 2 312 GLY 312 312 312 GLY GLY B . n 
B 2 313 LYS 313 313 313 LYS LYS B . n 
B 2 314 GLN 314 314 314 GLN GLN B . n 
B 2 315 LYS 315 315 315 LYS LYS B . n 
B 2 316 ASN 316 316 316 ASN ASN B . n 
B 2 317 LYS 317 317 317 LYS LYS B . n 
B 2 318 TYR 318 318 318 TYR TYR B . n 
B 2 319 TRP 319 319 319 TRP TRP B . n 
B 2 320 HIS 320 320 320 HIS HIS B . n 
B 2 321 PHE 321 321 321 PHE PHE B . n 
B 2 322 GLY 322 322 322 GLY GLY B . n 
B 2 323 ILE 323 323 323 ILE ILE B . n 
B 2 324 SER 324 324 324 SER SER B . n 
B 2 325 ALA 325 325 325 ALA ALA B . n 
B 2 326 ALA 326 326 326 ALA ALA B . n 
B 2 327 GLY 327 327 327 GLY GLY B . n 
B 2 328 LYS 328 328 328 LYS LYS B . n 
B 2 329 LEU 329 329 329 LEU LEU B . n 
B 2 330 TYR 330 330 330 TYR TYR B . n 
B 2 331 PRO 331 331 331 PRO PRO B . n 
B 2 332 SER 332 332 332 SER SER B . n 
B 2 333 PRO 333 333 333 PRO PRO B . n 
B 2 334 VAL 334 334 334 VAL VAL B . n 
B 2 335 LEU 335 335 335 LEU LEU B . n 
B 2 336 MET 336 336 336 MET MET B . n 
B 2 337 VAL 337 337 337 VAL VAL B . n 
B 2 338 SER 338 338 338 SER SER B . n 
B 2 339 SER 339 339 339 SER SER B . n 
B 2 340 HIS 340 340 340 HIS HIS B . n 
B 2 341 ILE 341 341 341 ILE ILE B . n 
B 2 342 ILE 342 342 342 ILE ILE B . n 
B 2 343 PHE 343 343 343 PHE PHE B . n 
B 2 344 THR 344 344 344 THR THR B . n 
B 2 345 MET 345 345 345 MET MET B . n 
B 2 346 ASP 346 346 346 ASP ASP B . n 
B 2 347 GLY 347 347 347 GLY GLY B . n 
B 2 348 ILE 348 348 348 ILE ILE B . n 
B 2 349 ASN 349 349 349 ASN ASN B . n 
B 2 350 LEU 350 350 350 LEU LEU B . n 
B 2 351 ILE 351 351 351 ILE ILE B . n 
B 2 352 LYS 352 352 352 LYS LYS B . n 
B 2 353 SER 353 353 353 SER SER B . n 
B 2 354 LYS 354 354 354 LYS LYS B . n 
B 2 355 SER 355 355 355 SER SER B . n 
B 2 356 ILE 356 356 356 ILE ILE B . n 
B 2 357 GLN 357 357 357 GLN GLN B . n 
B 2 358 HIS 358 358 358 HIS HIS B . n 
B 2 359 SER 359 359 359 SER SER B . n 
B 2 360 SER 360 360 360 SER SER B . n 
B 2 361 ARG 361 361 361 ARG ARG B . n 
B 2 362 ARG 362 362 362 ARG ARG B . n 
B 2 363 LYS 363 363 363 LYS LYS B . n 
B 2 364 GLN 364 364 364 GLN GLN B . n 
B 2 365 GLY 365 365 365 GLY GLY B . n 
B 2 366 LYS 366 366 366 LYS LYS B . n 
B 2 367 ASN 367 367 367 ASN ASN B . n 
B 2 368 TRP 368 368 368 TRP TRP B . n 
B 2 369 TRP 369 369 369 TRP TRP B . n 
B 2 370 ASN 370 370 370 ASN ASN B . n 
B 2 371 ASP 371 371 371 ASP ASP B . n 
B 2 372 LYS 372 372 372 LYS LYS B . n 
B 2 373 TRP 373 373 373 TRP TRP B . n 
B 2 374 ARG 374 374 374 ARG ARG B . n 
B 2 375 GLU 375 375 375 GLU GLU B . n 
B 2 376 LYS 376 376 376 LYS LYS B . n 
B 2 377 LEU 377 377 377 LEU LEU B . n 
B 2 378 LEU 378 378 378 LEU LEU B . n 
B 2 379 ALA 379 379 379 ALA ALA B . n 
B 2 380 PHE 380 380 380 PHE PHE B . n 
B 2 381 ILE 381 381 381 ILE ILE B . n 
B 2 382 ARG 382 382 382 ARG ARG B . n 
B 2 383 PHE 383 383 383 PHE PHE B . n 
B 2 384 LEU 384 384 384 LEU LEU B . n 
B 2 385 SER 385 385 385 SER SER B . n 
B 2 386 ASP 386 386 386 ASP ASP B . n 
B 2 387 ASP 387 387 387 ASP ASP B . n 
B 2 388 GLN 388 388 388 GLN GLN B . n 
B 2 389 ASN 389 389 389 ASN ASN B . n 
B 2 390 ALA 390 390 390 ALA ALA B . n 
B 2 391 ILE 391 391 391 ILE ILE B . n 
B 2 392 TYR 392 392 392 TYR TYR B . n 
B 2 393 LEU 393 393 393 LEU LEU B . n 
B 2 394 ASN 394 394 394 ASN ASN B . n 
B 2 395 VAL 395 395 395 VAL VAL B . n 
B 2 396 GLY 396 396 396 GLY GLY B . n 
B 2 397 SER 397 397 397 SER SER B . n 
B 2 398 GLU 398 398 398 GLU GLU B . n 
B 2 399 GLU 399 399 399 GLU GLU B . n 
B 2 400 LYS 400 400 400 LYS LYS B . n 
B 2 401 ILE 401 401 401 ILE ILE B . n 
B 2 402 LEU 402 402 402 LEU LEU B . n 
B 2 403 ILE 403 403 403 ILE ILE B . n 
B 2 404 SER 404 404 404 SER SER B . n 
B 2 405 ASN 405 405 405 ASN ASN B . n 
B 2 406 LYS 406 406 406 LYS LYS B . n 
B 2 407 PRO 407 407 407 PRO PRO B . n 
B 2 408 LEU 408 408 408 LEU LEU B . n 
B 2 409 LYS 409 409 409 LYS ALA B . n 
B 2 410 PHE 410 410 410 PHE PHE B . n 
B 2 411 PHE 411 411 411 PHE PHE B . n 
B 2 412 GLY 412 412 412 GLY GLY B . n 
B 2 413 LYS 413 413 413 LYS LYS B . n 
B 2 414 MET 414 414 414 MET MET B . n 
B 2 415 SER 415 415 415 SER SER B . n 
B 2 416 TYR 416 416 416 TYR TYR B . n 
B 2 417 VAL 417 417 417 VAL VAL B . n 
B 2 418 THR 418 418 418 THR THR B . n 
B 2 419 PRO 419 419 419 PRO PRO B . n 
B 2 420 SER 420 420 ?   ?   ?   B . n 
B 2 421 GLU 421 421 ?   ?   ?   B . n 
C 3 1   DT  1   1   1   DT  DT  C . n 
C 3 2   DG  2   2   2   DG  DG  C . n 
C 3 3   DA  3   3   3   DA  DA  C . n 
C 3 4   DG  4   4   4   DG  DG  C . n 
C 3 5   DG  5   5   5   DG  DG  C . n 
C 3 6   DT  6   6   6   DT  DT  C . n 
C 3 7   DA  7   7   7   DA  DA  C . n 
C 3 8   DG  8   8   8   DG  DG  C . n 
C 3 9   DT  9   9   9   DT  DT  C . n 
C 3 10  DA  10  10  10  DA  DA  C . n 
C 3 11  DG  11  11  11  DG  DG  C . n 
C 3 12  DG  12  12  12  DG  DG  C . n 
C 3 13  DT  13  13  13  DT  DT  C . n 
C 3 14  DT  14  14  14  DT  DT  C . n 
C 3 15  DG  15  15  15  DG  DG  C . n 
C 3 16  DT  16  16  16  DT  DT  C . n 
C 3 17  DA  17  17  17  DA  DA  C . n 
C 3 18  DT  18  18  18  DT  DT  C . n 
C 3 19  DA  19  19  19  DA  DA  C . n 
C 3 20  DG  20  20  20  DG  DG  C . n 
C 3 21  DT  21  21  21  DT  DT  C . n 
D 4 1   DT  1   2   ?   ?   ?   D . n 
D 4 2   DA  2   3   3   DA  DA  D . n 
D 4 3   DT  3   4   4   DT  DT  D . n 
D 4 4   DA  4   5   5   DA  DA  D . n 
D 4 5   DC  5   6   6   DC  DC  D . n 
D 4 6   DA  6   7   7   DA  DA  D . n 
D 4 7   DA  7   8   8   DA  DA  D . n 
D 4 8   DC  8   9   9   DC  DC  D . n 
D 4 9   DC  9   10  10  DC  DC  D . n 
D 4 10  DT  10  11  11  DT  DT  D . n 
D 4 11  DA  11  12  12  DA  DA  D . n 
D 4 12  DC  12  13  13  DC  DC  D . n 
D 4 13  DT  13  14  14  DT  DT  D . n 
D 4 14  DA  14  15  15  DA  DA  D . n 
D 4 15  DC  15  16  16  DC  DC  D . n 
D 4 16  DC  16  17  17  DC  DC  D . n 
D 4 17  DT  17  18  18  DT  DT  D . n 
D 4 18  DC  18  19  19  DC  DC  D . n 
D 4 19  DA  19  20  20  DA  DA  D . n 
D 4 20  DT  20  21  21  DT  DT  D . n 
# 
_pdbx_nonpoly_scheme.asym_id         E 
_pdbx_nonpoly_scheme.entity_id       5 
_pdbx_nonpoly_scheme.mon_id          MG 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     101 
_pdbx_nonpoly_scheme.auth_seq_num    1 
_pdbx_nonpoly_scheme.pdb_mon_id      MG 
_pdbx_nonpoly_scheme.auth_mon_id     MG 
_pdbx_nonpoly_scheme.pdb_strand_id   D 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A LYS 392 ? CG  ? A LYS 392 CG  
2  1 Y 1 A LYS 392 ? CD  ? A LYS 392 CD  
3  1 Y 1 A LYS 392 ? CE  ? A LYS 392 CE  
4  1 Y 1 A LYS 392 ? NZ  ? A LYS 392 NZ  
5  1 Y 1 B ARG 114 ? CG  ? B ARG 114 CG  
6  1 Y 1 B ARG 114 ? CD  ? B ARG 114 CD  
7  1 Y 1 B ARG 114 ? NE  ? B ARG 114 NE  
8  1 Y 1 B ARG 114 ? CZ  ? B ARG 114 CZ  
9  1 Y 1 B ARG 114 ? NH1 ? B ARG 114 NH1 
10 1 Y 1 B ARG 114 ? NH2 ? B ARG 114 NH2 
11 1 Y 1 B HIS 160 ? CG  ? B HIS 160 CG  
12 1 Y 1 B HIS 160 ? ND1 ? B HIS 160 ND1 
13 1 Y 1 B HIS 160 ? CD2 ? B HIS 160 CD2 
14 1 Y 1 B HIS 160 ? CE1 ? B HIS 160 CE1 
15 1 Y 1 B HIS 160 ? NE2 ? B HIS 160 NE2 
16 1 Y 1 B ASP 161 ? CG  ? B ASP 161 CG  
17 1 Y 1 B ASP 161 ? OD1 ? B ASP 161 OD1 
18 1 Y 1 B ASP 161 ? OD2 ? B ASP 161 OD2 
19 1 Y 1 B LYS 162 ? CG  ? B LYS 162 CG  
20 1 Y 1 B LYS 162 ? CD  ? B LYS 162 CD  
21 1 Y 1 B LYS 162 ? CE  ? B LYS 162 CE  
22 1 Y 1 B LYS 162 ? NZ  ? B LYS 162 NZ  
23 1 Y 1 B ILE 165 ? CG1 ? B ILE 165 CG1 
24 1 Y 1 B ILE 165 ? CG2 ? B ILE 165 CG2 
25 1 Y 1 B ILE 165 ? CD1 ? B ILE 165 CD1 
26 1 Y 1 B GLU 166 ? CG  ? B GLU 166 CG  
27 1 Y 1 B GLU 166 ? CD  ? B GLU 166 CD  
28 1 Y 1 B GLU 166 ? OE1 ? B GLU 166 OE1 
29 1 Y 1 B GLU 166 ? OE2 ? B GLU 166 OE2 
30 1 Y 1 B LYS 167 ? CG  ? B LYS 167 CG  
31 1 Y 1 B LYS 167 ? CD  ? B LYS 167 CD  
32 1 Y 1 B LYS 167 ? CE  ? B LYS 167 CE  
33 1 Y 1 B LYS 167 ? NZ  ? B LYS 167 NZ  
34 1 Y 1 B GLU 168 ? CG  ? B GLU 168 CG  
35 1 Y 1 B GLU 168 ? CD  ? B GLU 168 CD  
36 1 Y 1 B GLU 168 ? OE1 ? B GLU 168 OE1 
37 1 Y 1 B GLU 168 ? OE2 ? B GLU 168 OE2 
38 1 Y 1 B ARG 193 ? CG  ? B ARG 193 CG  
39 1 Y 1 B ARG 193 ? CD  ? B ARG 193 CD  
40 1 Y 1 B ARG 193 ? NE  ? B ARG 193 NE  
41 1 Y 1 B ARG 193 ? CZ  ? B ARG 193 CZ  
42 1 Y 1 B ARG 193 ? NH1 ? B ARG 193 NH1 
43 1 Y 1 B ARG 193 ? NH2 ? B ARG 193 NH2 
44 1 Y 1 B LYS 289 ? CG  ? B LYS 289 CG  
45 1 Y 1 B LYS 289 ? CD  ? B LYS 289 CD  
46 1 Y 1 B LYS 289 ? CE  ? B LYS 289 CE  
47 1 Y 1 B LYS 289 ? NZ  ? B LYS 289 NZ  
48 1 Y 1 B LYS 366 ? CG  ? B LYS 366 CG  
49 1 Y 1 B LYS 366 ? CD  ? B LYS 366 CD  
50 1 Y 1 B LYS 366 ? CE  ? B LYS 366 CE  
51 1 Y 1 B LYS 366 ? NZ  ? B LYS 366 NZ  
52 1 Y 1 B LYS 409 ? CG  ? B LYS 409 CG  
53 1 Y 1 B LYS 409 ? CD  ? B LYS 409 CD  
54 1 Y 1 B LYS 409 ? CE  ? B LYS 409 CE  
55 1 Y 1 B LYS 409 ? NZ  ? B LYS 409 NZ  
56 1 Y 1 B PHE 411 ? CG  ? B PHE 411 CG  
57 1 Y 1 B PHE 411 ? CD1 ? B PHE 411 CD1 
58 1 Y 1 B PHE 411 ? CD2 ? B PHE 411 CD2 
59 1 Y 1 B PHE 411 ? CE1 ? B PHE 411 CE1 
60 1 Y 1 B PHE 411 ? CE2 ? B PHE 411 CE2 
61 1 Y 1 B PHE 411 ? CZ  ? B PHE 411 CZ  
62 1 Y 1 D DA  3   ? P   ? D DA  2   P   
63 1 Y 1 D DA  3   ? OP1 ? D DA  2   OP1 
64 1 Y 1 D DA  3   ? OP2 ? D DA  2   OP2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? 'model building' ? ? ? ? ? ? ? ? ? ? ? Coot     ? ? ? 0.7.2.1     1 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? 1.17.1_3660 2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? HKL-3000 ? ? ? 7.21        3 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? HKL-3000 ? ? ? 7.21        4 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? 1.17.1_3660 5 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  120.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9L9W 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     136.189 
_cell.length_a_esd                 ? 
_cell.length_b                     136.189 
_cell.length_b_esd                 ? 
_cell.length_c                     174.919 
_cell.length_c_esd                 ? 
_cell.volume                       2809646.484 
_cell.volume_esd                   ? 
_cell.Z_PDB                        6 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9L9W 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                154 
_symmetry.space_group_name_Hall            
;P 32 2"
;
_symmetry.space_group_name_H-M             'P 32 2 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9L9W 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.88 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          68.27 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.1 M BICINE, pH=8.5, 4.4% PEG4000' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            291 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2024-12-16 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.97918 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRF BEAMLINE BL10U2' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.97918 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL10U2 
_diffrn_source.pdbx_synchrotron_site       SSRF 
# 
_reflns.B_iso_Wilson_estimate                          295.22 
_reflns.entry_id                                       9L9W 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              5.87 
_reflns.d_resolution_low                               39.32 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     5233 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.6 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                17.6 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          7.50 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                0.059 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   ? 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    5.87 
_reflns_shell.d_res_low                                     6.02 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             371 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               0.903 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  ? 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          100 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               317.20 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9L9W 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            5.87 
_refine.ls_d_res_low                             39.31 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     5233 
_refine.ls_number_reflns_R_free                  265 
_refine.ls_number_reflns_R_work                  4968 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    98.92 
_refine.ls_percent_reflns_R_free                 5.06 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2625 
_refine.ls_R_factor_R_free                       0.2884 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2610 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.34 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1100 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 26.8662 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            1.0505 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       5.87 
_refine_hist.d_res_low                        39.31 
_refine_hist.number_atoms_solvent             0 
_refine_hist.number_atoms_total               8099 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        7279 
_refine_hist.pdbx_number_atoms_nucleic_acid   819 
_refine_hist.pdbx_number_atoms_ligand         1 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0157  ? 8379  ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.5200  ? 11508 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0687  ? 1249  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0089  ? 1321  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 28.1014 ? 3173  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 5.87 7.38  . . 137 2439 99.31 . . . . 0.3208 . . . . . . . . . . . 0.3923 
'X-RAY DIFFRACTION' 7.39 39.31 . . 128 2529 98.55 . . . . 0.2440 . . . . . . . . . . . 0.2555 
# 
_struct.entry_id                     9L9W 
_struct.title                        'Structure of SPARTA in complex with guide DNA and a 19nt target DNA' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9L9W 
_struct_keywords.text            'Ago, TIR-APAZ, DNA, NADase, DNA BINDING PROTEIN/DNA, DNA BINDING PROTEIN-DNA complex' 
_struct_keywords.pdbx_keywords   'DNA BINDING PROTEIN/DNA' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP A0A1I7NFD7_9BACT A0A1I7NFD7 ? 1 
;MKELIYIEEPSILFAHGQKCTDPRDGLALFGPLNQIYGIKSGVVGTQKGLQIFKSYLDKIQKPIYNHNNITRPMFPGFEA
VFGCKWESQNIVFKEITDEEIRRYLFNASTHKRTYDLVTLFNDKIITANKNDEERVDVWFVIVPEEIYKYCRPNSVLPNE
LVQTKSLISKSKAKSFRYTPTLFEEFNKKLKEVEKEAKTYNYDAQFHDQLKARLLEHTIPTQILRESTLAWRDFKNTFGA
PIRDFSKIEGHLAWTISTAAYYKAGGKPWKLGDIRPGVCYLGLVYKKIEKSKNPQNACCAAQMFLDNGDGTVFKGEVGPW
YNPEKGEYHLKPKEAKALLTQALESYKEQNKSYPKEVFIHARTRFNDEEWNAFNEVTPKNTNLVGVTITKSKPLKLYKTE
GAFPIMRGNAYIVDEKKAFLWTLGFVPKLQSTLSMEVPNPIFIEINKGEAEIQQVLKDILALTKLNYNACIYADGEPVTL
RFANKIGEILTASTEIKTPPLAFKYYI
;
1 
2 UNP A0A1I7NFG5_9BACT A0A1I7NFG5 ? 2 
;MRNKIFISHATPEDDDFTRWLSLKLIGLGYEVWCDILFLDKGVDFWSTIEKEIRENTCKFLIVSSTAGNKREGVLKELAV
ATKVKKHLQDDMFIIPLAIDENLSYDDINIEIVRLNAIDFKKSWAKGLQDLLDAFEKQNVPKKPPDHSKSNLLYQQIFLH
DKQAIEKEETYDSNWFPIISFPNELRFHRYDWRLPKQFDVRTLAFPAIRYKEYLCTFAWEYDFIHQLPKTETYNGQESIR
ISTSDILSGRYDTDFIRNYECQRLIVQLINKAFELRMKDKNVREYQMSKTFAYWIEKGKLEKDKFEKIKLVGKQKNKYWH
FGISAAGKLYPSPVLMVSSHIIFTMDGINLIKSKSIQHSSRRKQGKNWWNDKWREKLLAFIRFLSDDQNAIYLNVGSEEK
ILISNKPLKFFGKMSYVTPSE
;
1 
3 PDB 9L9W             9L9W       ? 3 ? 1 
4 PDB 9L9W             9L9W       ? 4 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9L9W A 1 ? 507 ? A0A1I7NFD7 1 ? 507 ? 1 507 
2 2 9L9W B 1 ? 421 ? A0A1I7NFG5 1 ? 421 ? 1 421 
3 3 9L9W C 1 ? 21  ? 9L9W       1 ? 21  ? 1 21  
4 4 9L9W D 1 ? 20  ? 9L9W       2 ? 21  ? 2 21  
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 10760 ? 
1 MORE         -77   ? 
1 'SSA (A^2)'  44080 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ALA A 15  ? GLY A 17  ? ALA A 15  GLY A 17  5 ? 3  
HELX_P HELX_P2  AA2 ASP A 22  ? GLY A 31  ? ASP A 22  GLY A 31  1 ? 10 
HELX_P HELX_P3  AA3 THR A 46  ? LYS A 62  ? THR A 46  LYS A 62  1 ? 17 
HELX_P HELX_P4  AA4 GLY A 77  ? GLY A 83  ? GLY A 77  GLY A 83  1 ? 7  
HELX_P HELX_P5  AA5 THR A 97  ? PHE A 106 ? THR A 97  PHE A 106 1 ? 10 
HELX_P HELX_P6  AA6 SER A 109 ? ASP A 132 ? SER A 109 ASP A 132 1 ? 24 
HELX_P HELX_P7  AA7 PRO A 144 ? CYS A 151 ? PRO A 144 CYS A 151 1 ? 8  
HELX_P HELX_P8  AA8 GLN A 205 ? LEU A 214 ? GLN A 205 LEU A 214 1 ? 10 
HELX_P HELX_P9  AA9 GLU A 226 ? ALA A 230 ? GLU A 226 ALA A 230 1 ? 5  
HELX_P HELX_P10 AB1 TRP A 231 ? PHE A 234 ? TRP A 231 PHE A 234 5 ? 4  
HELX_P HELX_P11 AB2 ILE A 248 ? GLY A 265 ? ILE A 248 GLY A 265 1 ? 18 
HELX_P HELX_P12 AB3 LYS A 331 ? LYS A 351 ? LYS A 331 LYS A 351 1 ? 21 
HELX_P HELX_P13 AB4 ASN A 366 ? THR A 377 ? ASN A 366 THR A 377 1 ? 12 
HELX_P HELX_P14 AB5 GLU A 451 ? THR A 463 ? GLU A 451 THR A 463 1 ? 13 
HELX_P HELX_P15 AB6 LYS A 464 ? ASN A 466 ? LYS A 464 ASN A 466 5 ? 3  
HELX_P HELX_P16 AB7 PRO A 477 ? PHE A 482 ? PRO A 477 PHE A 482 1 ? 6  
HELX_P HELX_P17 AB8 PHE A 482 ? SER A 493 ? PHE A 482 SER A 493 1 ? 12 
HELX_P HELX_P18 AB9 PHE A 503 ? ILE A 507 ? PHE A 503 ILE A 507 1 ? 5  
HELX_P HELX_P19 AC1 ASP B 14  ? GLY B 29  ? ASP B 14  GLY B 29  1 ? 16 
HELX_P HELX_P20 AC2 VAL B 43  ? GLU B 55  ? VAL B 43  GLU B 55  1 ? 13 
HELX_P HELX_P21 AC3 SER B 65  ? LYS B 70  ? SER B 65  LYS B 70  1 ? 6  
HELX_P HELX_P22 AC4 ARG B 71  ? GLN B 89  ? ARG B 71  GLN B 89  1 ? 19 
HELX_P HELX_P23 AC5 ASP B 90  ? MET B 92  ? ASP B 90  MET B 92  5 ? 3  
HELX_P HELX_P24 AC6 ASN B 109 ? ARG B 114 ? ASN B 109 ARG B 114 1 ? 6  
HELX_P HELX_P25 AC7 SER B 123 ? GLN B 138 ? SER B 123 GLN B 138 1 ? 16 
HELX_P HELX_P26 AC8 ASP B 146 ? ILE B 157 ? ASP B 146 ILE B 157 1 ? 12 
HELX_P HELX_P27 AC9 PHE B 158 ? ASP B 161 ? PHE B 158 ASP B 161 5 ? 4  
HELX_P HELX_P28 AD1 TYR B 190 ? LEU B 194 ? TYR B 190 LEU B 194 5 ? 5  
HELX_P HELX_P29 AD2 TRP B 219 ? PHE B 223 ? TRP B 219 PHE B 223 5 ? 5  
HELX_P HELX_P30 AD3 THR B 243 ? LEU B 247 ? THR B 243 LEU B 247 1 ? 5  
HELX_P HELX_P31 AD4 ARG B 257 ? MET B 277 ? ARG B 257 MET B 277 1 ? 21 
HELX_P HELX_P32 AD5 LYS B 278 ? LYS B 280 ? LYS B 278 LYS B 280 5 ? 3  
HELX_P HELX_P33 AD6 LEU B 300 ? LYS B 304 ? LEU B 300 LYS B 304 5 ? 5  
HELX_P HELX_P34 AD7 SER B 353 ? LYS B 366 ? SER B 353 LYS B 366 1 ? 14 
HELX_P HELX_P35 AD8 TRP B 369 ? SER B 385 ? TRP B 369 SER B 385 1 ? 17 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
hydrog1  hydrog ? ? C DT 1  N3 ? ? ? 1_555 D DT 20 O4 ? ? C DT 1  D DT 21 1_555 ? ? ? ? ? ? TYPE_12_PAIR    ? ? ? 
hydrog2  hydrog ? ? C DT 1  O4 ? ? ? 1_555 D DT 20 N3 ? ? C DT 1  D DT 21 1_555 ? ? ? ? ? ? TYPE_12_PAIR    ? ? ? 
hydrog3  hydrog ? ? C DG 2  N2 ? ? ? 1_555 D DC 18 O2 ? ? C DG 2  D DC 19 1_555 ? ? ? ? ? ? 'DG-DC PAIR'    ? ? ? 
hydrog4  hydrog ? ? C DA 3  N1 ? ? ? 1_555 D DT 17 N3 ? ? C DA 3  D DT 18 1_555 ? ? ? ? ? ? WATSON-CRICK    ? ? ? 
hydrog5  hydrog ? ? C DA 3  N6 ? ? ? 1_555 D DT 17 O4 ? ? C DA 3  D DT 18 1_555 ? ? ? ? ? ? WATSON-CRICK    ? ? ? 
hydrog6  hydrog ? ? C DG 4  N1 ? ? ? 1_555 D DC 16 N3 ? ? C DG 4  D DC 17 1_555 ? ? ? ? ? ? WATSON-CRICK    ? ? ? 
hydrog7  hydrog ? ? C DG 4  N2 ? ? ? 1_555 D DC 16 O2 ? ? C DG 4  D DC 17 1_555 ? ? ? ? ? ? WATSON-CRICK    ? ? ? 
hydrog8  hydrog ? ? C DG 4  O6 ? ? ? 1_555 D DC 16 N4 ? ? C DG 4  D DC 17 1_555 ? ? ? ? ? ? WATSON-CRICK    ? ? ? 
hydrog9  hydrog ? ? C DG 5  N1 ? ? ? 1_555 D DC 15 N3 ? ? C DG 5  D DC 16 1_555 ? ? ? ? ? ? WATSON-CRICK    ? ? ? 
hydrog10 hydrog ? ? C DG 5  N2 ? ? ? 1_555 D DC 15 O2 ? ? C DG 5  D DC 16 1_555 ? ? ? ? ? ? WATSON-CRICK    ? ? ? 
hydrog11 hydrog ? ? C DG 5  O6 ? ? ? 1_555 D DC 15 N4 ? ? C DG 5  D DC 16 1_555 ? ? ? ? ? ? WATSON-CRICK    ? ? ? 
hydrog12 hydrog ? ? C DT 6  N3 ? ? ? 1_555 D DA 14 N1 ? ? C DT 6  D DA 15 1_555 ? ? ? ? ? ? WATSON-CRICK    ? ? ? 
hydrog13 hydrog ? ? C DT 6  O4 ? ? ? 1_555 D DA 14 N6 ? ? C DT 6  D DA 15 1_555 ? ? ? ? ? ? WATSON-CRICK    ? ? ? 
hydrog14 hydrog ? ? C DA 7  N1 ? ? ? 1_555 D DT 13 N3 ? ? C DA 7  D DT 14 1_555 ? ? ? ? ? ? WATSON-CRICK    ? ? ? 
hydrog15 hydrog ? ? C DA 7  N6 ? ? ? 1_555 D DT 13 O4 ? ? C DA 7  D DT 14 1_555 ? ? ? ? ? ? WATSON-CRICK    ? ? ? 
hydrog16 hydrog ? ? C DG 8  O6 ? ? ? 1_555 D DA 11 N6 ? ? C DG 8  D DA 12 1_555 ? ? ? ? ? ? 'DG-DA MISPAIR' ? ? ? 
hydrog17 hydrog ? ? C DG 8  O6 ? ? ? 1_555 D DC 12 N4 ? ? C DG 8  D DC 13 1_555 ? ? ? ? ? ? 'DG-DC PAIR'    ? ? ? 
hydrog18 hydrog ? ? C DT 9  N3 ? ? ? 1_555 D DA 11 N1 ? ? C DT 9  D DA 12 1_555 ? ? ? ? ? ? WATSON-CRICK    ? ? ? 
hydrog19 hydrog ? ? C DT 9  O4 ? ? ? 1_555 D DA 11 N6 ? ? C DT 9  D DA 12 1_555 ? ? ? ? ? ? WATSON-CRICK    ? ? ? 
hydrog20 hydrog ? ? C DA 10 N1 ? ? ? 1_555 D DT 10 N3 ? ? C DA 10 D DT 11 1_555 ? ? ? ? ? ? WATSON-CRICK    ? ? ? 
hydrog21 hydrog ? ? C DA 10 N6 ? ? ? 1_555 D DT 10 O4 ? ? C DA 10 D DT 11 1_555 ? ? ? ? ? ? WATSON-CRICK    ? ? ? 
hydrog22 hydrog ? ? C DG 11 N1 ? ? ? 1_555 D DC 9  N3 ? ? C DG 11 D DC 10 1_555 ? ? ? ? ? ? WATSON-CRICK    ? ? ? 
hydrog23 hydrog ? ? C DG 11 N2 ? ? ? 1_555 D DC 9  O2 ? ? C DG 11 D DC 10 1_555 ? ? ? ? ? ? WATSON-CRICK    ? ? ? 
hydrog24 hydrog ? ? C DG 11 O6 ? ? ? 1_555 D DC 9  N4 ? ? C DG 11 D DC 10 1_555 ? ? ? ? ? ? WATSON-CRICK    ? ? ? 
hydrog25 hydrog ? ? C DG 12 N1 ? ? ? 1_555 D DC 8  N3 ? ? C DG 12 D DC 9  1_555 ? ? ? ? ? ? 'DG-DC PAIR'    ? ? ? 
hydrog26 hydrog ? ? C DG 12 N2 ? ? ? 1_555 D DC 9  O2 ? ? C DG 12 D DC 10 1_555 ? ? ? ? ? ? 'DG-DC PAIR'    ? ? ? 
hydrog27 hydrog ? ? C DT 13 O4 ? ? ? 1_555 D DA 7  N6 ? ? C DT 13 D DA 8  1_555 ? ? ? ? ? ? 'DT-DA PAIR'    ? ? ? 
hydrog28 hydrog ? ? C DT 14 N3 ? ? ? 1_555 D DA 6  N1 ? ? C DT 14 D DA 7  1_555 ? ? ? ? ? ? WATSON-CRICK    ? ? ? 
hydrog29 hydrog ? ? C DT 14 O4 ? ? ? 1_555 D DA 6  N6 ? ? C DT 14 D DA 7  1_555 ? ? ? ? ? ? WATSON-CRICK    ? ? ? 
hydrog30 hydrog ? ? C DG 15 N1 ? ? ? 1_555 D DC 5  N3 ? ? C DG 15 D DC 6  1_555 ? ? ? ? ? ? WATSON-CRICK    ? ? ? 
hydrog31 hydrog ? ? C DG 15 N2 ? ? ? 1_555 D DC 5  O2 ? ? C DG 15 D DC 6  1_555 ? ? ? ? ? ? WATSON-CRICK    ? ? ? 
hydrog32 hydrog ? ? C DG 15 O6 ? ? ? 1_555 D DC 5  N4 ? ? C DG 15 D DC 6  1_555 ? ? ? ? ? ? WATSON-CRICK    ? ? ? 
hydrog33 hydrog ? ? C DT 16 N3 ? ? ? 1_555 D DA 4  N1 ? ? C DT 16 D DA 5  1_555 ? ? ? ? ? ? WATSON-CRICK    ? ? ? 
hydrog34 hydrog ? ? C DT 16 O4 ? ? ? 1_555 D DA 4  N6 ? ? C DT 16 D DA 5  1_555 ? ? ? ? ? ? WATSON-CRICK    ? ? ? 
hydrog35 hydrog ? ? C DA 17 N1 ? ? ? 1_555 D DA 2  N6 ? ? C DA 17 D DA 3  1_555 ? ? ? ? ? ? 'DA-DA MISPAIR' ? ? ? 
hydrog36 hydrog ? ? C DA 17 N1 ? ? ? 1_555 D DT 3  N3 ? ? C DA 17 D DT 4  1_555 ? ? ? ? ? ? 'DA-DT PAIR'    ? ? ? 
hydrog37 hydrog ? ? C DT 18 N3 ? ? ? 1_555 D DA 2  N1 ? ? C DT 18 D DA 3  1_555 ? ? ? ? ? ? WATSON-CRICK    ? ? ? 
hydrog38 hydrog ? ? C DT 18 O4 ? ? ? 1_555 D DA 2  N6 ? ? C DT 18 D DA 3  1_555 ? ? ? ? ? ? WATSON-CRICK    ? ? ? 
# 
_struct_conn_type.id          hydrog 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 THR 11  B . ? THR 11  B PRO 12  B ? PRO 12  B 1 3.61 
2 TYR 330 B . ? TYR 330 B PRO 331 B ? PRO 331 B 1 1.47 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4  ? 
AA2 ? 10 ? 
AA3 ? 3  ? 
AA4 ? 4  ? 
AA5 ? 2  ? 
AA6 ? 2  ? 
AA7 ? 5  ? 
AA8 ? 5  ? 
AA9 ? 4  ? 
AB1 ? 4  ? 
AB2 ? 5  ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2  ? parallel      
AA1 2 3  ? anti-parallel 
AA1 3 4  ? anti-parallel 
AA2 1 2  ? anti-parallel 
AA2 2 3  ? anti-parallel 
AA2 3 4  ? anti-parallel 
AA2 4 5  ? anti-parallel 
AA2 5 6  ? parallel      
AA2 6 7  ? parallel      
AA2 7 8  ? anti-parallel 
AA2 8 9  ? anti-parallel 
AA2 9 10 ? anti-parallel 
AA3 1 2  ? anti-parallel 
AA3 2 3  ? anti-parallel 
AA4 1 2  ? parallel      
AA4 2 3  ? parallel      
AA4 3 4  ? parallel      
AA5 1 2  ? anti-parallel 
AA6 1 2  ? anti-parallel 
AA7 1 2  ? parallel      
AA7 2 3  ? parallel      
AA7 3 4  ? parallel      
AA7 4 5  ? parallel      
AA8 1 2  ? anti-parallel 
AA8 2 3  ? anti-parallel 
AA8 3 4  ? anti-parallel 
AA8 4 5  ? anti-parallel 
AA9 1 2  ? anti-parallel 
AA9 2 3  ? anti-parallel 
AA9 3 4  ? anti-parallel 
AB1 1 2  ? anti-parallel 
AB1 2 3  ? anti-parallel 
AB1 3 4  ? anti-parallel 
AB2 1 2  ? anti-parallel 
AB2 2 3  ? anti-parallel 
AB2 3 4  ? anti-parallel 
AB2 4 5  ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1  LYS A 2   ? GLU A 3   ? LYS A 2   GLU A 3   
AA1 2  LYS B 409 ? SER B 415 ? LYS B 409 SER B 415 
AA1 3  ILE B 165 ? ASP B 172 ? ILE B 165 ASP B 172 
AA1 4  TYR A 397 ? LYS A 398 ? TYR A 397 LYS A 398 
AA2 1  ILE A 5   ? TYR A 6   ? ILE A 5   TYR A 6   
AA2 2  ASN A 409 ? ILE A 412 ? ASN A 409 ILE A 412 
AA2 3  LYS A 417 ? LEU A 420 ? LYS A 417 LEU A 420 
AA2 4  ILE A 441 ? GLU A 444 ? ILE A 441 GLU A 444 
AA2 5  ASN A 382 ? THR A 389 ? ASN A 382 THR A 389 
AA2 6  GLU A 356 ? ALA A 361 ? GLU A 356 ALA A 361 
AA2 7  VAL A 278 ? LYS A 287 ? VAL A 278 LYS A 287 
AA2 8  ASN A 296 ? PHE A 304 ? ASN A 296 PHE A 304 
AA2 9  THR A 311 ? PRO A 319 ? THR A 311 PRO A 319 
AA2 10 LEU A 501 ? ALA A 502 ? LEU A 501 ALA A 502 
AA3 1  GLN A 18  ? CYS A 20  ? GLN A 18  CYS A 20  
AA3 2  ILE A 12  ? PHE A 14  ? ILE A 12  PHE A 14  
AA3 3  LYS A 270 ? LEU A 271 ? LYS A 270 LEU A 271 
AA4 1  ILE A 91  ? PHE A 93  ? ILE A 91  PHE A 93  
AA4 2  SER A 41  ? VAL A 43  ? SER A 41  VAL A 43  
AA4 3  VAL A 138 ? VAL A 143 ? VAL A 138 VAL A 143 
AA4 4  THR A 221 ? ARG A 225 ? THR A 221 ARG A 225 
AA5 1  TYR A 321 ? ASN A 322 ? TYR A 321 ASN A 322 
AA5 2  GLU A 327 ? TYR A 328 ? GLU A 327 TYR A 328 
AA6 1  PHE A 425 ? VAL A 426 ? PHE A 425 VAL A 426 
AA6 2  SER A 431 ? THR A 432 ? SER A 431 THR A 432 
AA7 1  VAL B 32  ? TRP B 33  ? VAL B 32  TRP B 33  
AA7 2  LYS B 4   ? SER B 8   ? LYS B 4   SER B 8   
AA7 3  THR B 57  ? VAL B 63  ? THR B 57  VAL B 63  
AA7 4  ILE B 94  ? ALA B 98  ? ILE B 94  ALA B 98  
AA7 5  ILE B 118 ? ASP B 119 ? ILE B 118 ASP B 119 
AA8 1  ALA B 326 ? LYS B 328 ? ALA B 326 LYS B 328 
AA8 2  VAL B 334 ? MET B 336 ? VAL B 334 MET B 336 
AA8 3  TRP B 175 ? SER B 180 ? TRP B 175 SER B 180 
AA8 4  LYS B 400 ? SER B 404 ? LYS B 400 SER B 404 
AA8 5  ALA B 390 ? ASN B 394 ? ALA B 390 ASN B 394 
AA9 1  ILE B 208 ? TYR B 210 ? ILE B 208 TYR B 210 
AA9 2  TYR B 213 ? THR B 216 ? TYR B 213 THR B 216 
AA9 3  GLU B 184 ? HIS B 188 ? GLU B 184 HIS B 188 
AA9 4  ILE B 239 ? SER B 242 ? ILE B 239 SER B 242 
AB1 1  ARG B 283 ? GLN B 286 ? ARG B 283 GLN B 286 
AB1 2  PHE B 291 ? TRP B 294 ? PHE B 291 TRP B 294 
AB1 3  LYS B 317 ? ILE B 323 ? LYS B 317 ILE B 323 
AB1 4  VAL B 311 ? GLN B 314 ? VAL B 311 GLN B 314 
AB2 1  ARG B 283 ? GLN B 286 ? ARG B 283 GLN B 286 
AB2 2  PHE B 291 ? TRP B 294 ? PHE B 291 TRP B 294 
AB2 3  LYS B 317 ? ILE B 323 ? LYS B 317 ILE B 323 
AB2 4  SER B 339 ? ASP B 346 ? SER B 339 ASP B 346 
AB2 5  ASN B 349 ? LEU B 350 ? ASN B 349 LEU B 350 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2  N LYS A 2   ? N LYS A 2   O PHE B 411 ? O PHE B 411 
AA1 2 3  O MET B 414 ? O MET B 414 N LYS B 167 ? N LYS B 167 
AA1 3 4  O ASP B 172 ? O ASP B 172 N TYR A 397 ? N TYR A 397 
AA2 1 2  N ILE A 5   ? N ILE A 5   O ALA A 410 ? O ALA A 410 
AA2 2 3  N TYR A 411 ? N TYR A 411 O PHE A 419 ? O PHE A 419 
AA2 3 4  N LEU A 420 ? N LEU A 420 O ILE A 441 ? O ILE A 441 
AA2 4 5  O GLU A 444 ? O GLU A 444 N THR A 387 ? N THR A 387 
AA2 5 6  O VAL A 384 ? O VAL A 384 N ILE A 359 ? N ILE A 359 
AA2 6 7  O HIS A 360 ? O HIS A 360 N LEU A 281 ? N LEU A 281 
AA2 7 8  N GLY A 282 ? N GLY A 282 O GLN A 302 ? O GLN A 302 
AA2 8 9  N ALA A 301 ? N ALA A 301 O PHE A 313 ? O PHE A 313 
AA2 9 10 N VAL A 312 ? N VAL A 312 O LEU A 501 ? O LEU A 501 
AA3 1 2  O GLN A 18  ? O GLN A 18  N PHE A 14  ? N PHE A 14  
AA3 2 3  N LEU A 13  ? N LEU A 13  O LYS A 270 ? O LYS A 270 
AA4 1 2  O VAL A 92  ? O VAL A 92  N SER A 41  ? N SER A 41  
AA4 2 3  N GLY A 42  ? N GLY A 42  O PHE A 140 ? O PHE A 140 
AA4 3 4  N TRP A 139 ? N TRP A 139 O GLN A 222 ? O GLN A 222 
AA5 1 2  N ASN A 322 ? N ASN A 322 O GLU A 327 ? O GLU A 327 
AA6 1 2  N VAL A 426 ? N VAL A 426 O SER A 431 ? O SER A 431 
AA7 1 2  O TRP B 33  ? O TRP B 33  N ILE B 7   ? N ILE B 7   
AA7 2 3  N SER B 8   ? N SER B 8   O LEU B 61  ? O LEU B 61  
AA7 3 4  N ILE B 62  ? N ILE B 62  O LEU B 97  ? O LEU B 97  
AA7 4 5  N ALA B 98  ? N ALA B 98  O ILE B 118 ? O ILE B 118 
AA8 1 2  N ALA B 326 ? N ALA B 326 O MET B 336 ? O MET B 336 
AA8 2 3  O LEU B 335 ? O LEU B 335 N PHE B 176 ? N PHE B 176 
AA8 3 4  N ILE B 179 ? N ILE B 179 O LEU B 402 ? O LEU B 402 
AA8 4 5  O ILE B 403 ? O ILE B 403 N ILE B 391 ? N ILE B 391 
AA9 1 2  N ILE B 208 ? N ILE B 208 O CYS B 215 ? O CYS B 215 
AA9 2 3  O LEU B 214 ? O LEU B 214 N HIS B 188 ? N HIS B 188 
AA9 3 4  N LEU B 185 ? N LEU B 185 O ILE B 241 ? O ILE B 241 
AB1 1 2  N TYR B 285 ? N TYR B 285 O ALA B 292 ? O ALA B 292 
AB1 2 3  N TYR B 293 ? N TYR B 293 O ILE B 323 ? O ILE B 323 
AB1 3 4  O LYS B 317 ? O LYS B 317 N GLN B 314 ? N GLN B 314 
AB2 1 2  N TYR B 285 ? N TYR B 285 O ALA B 292 ? O ALA B 292 
AB2 2 3  N TYR B 293 ? N TYR B 293 O ILE B 323 ? O ILE B 323 
AB2 3 4  N TYR B 318 ? N TYR B 318 O THR B 344 ? O THR B 344 
AB2 4 5  N ASP B 346 ? N ASP B 346 O ASN B 349 ? O ASN B 349 
# 
_pdbx_entry_details.entry_id                   9L9W 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1  1 OG1 A THR 399 ? ? O   B THR 170 ? ? 1.94 
2  1 OE2 A GLU 344 ? ? OH  A TYR 353 ? ? 1.95 
3  1 OH  A TYR 262 ? ? OD1 A ASP 309 ? ? 1.99 
4  1 NZ  A LYS 59  ? ? OE1 A GLU 249 ? ? 2.01 
5  1 O   B GLU 184 ? ? NH2 B ARG 186 ? ? 2.04 
6  1 NE2 A GLN 302 ? ? O   A THR 479 ? ? 2.04 
7  1 OG1 A THR 432 ? ? O   A SER 434 ? ? 2.04 
8  1 O   A PRO 404 ? ? OH  B TYR 416 ? ? 2.05 
9  1 O6  C DG  12  ? ? N4  D DC  9   ? ? 2.08 
10 1 OE1 A GLU 9   ? ? NZ  A LYS 464 ? ? 2.08 
11 1 O   B SER 65  ? ? ND2 B ASN 69  ? ? 2.12 
12 1 O   A TRP 254 ? ? OG1 A THR 258 ? ? 2.13 
13 1 NE  A ARG 225 ? ? OG  A SER 227 ? ? 2.13 
14 1 OE2 A GLU 327 ? ? NE2 A HIS 329 ? ? 2.14 
15 1 O   B ASP 44  ? ? N   B THR 48  ? ? 2.15 
16 1 O   B THR 18  ? ? OG  B SER 22  ? ? 2.17 
17 1 O   A ALA 253 ? ? OG  A SER 257 ? ? 2.17 
18 1 O   A LYS 336 ? ? OG1 A THR 340 ? ? 2.18 
19 1 NZ  B LYS 4   ? ? OE1 B GLU 52  ? ? 2.18 
20 1 O   A SER 257 ? ? N   A TYR 261 ? ? 2.18 
21 1 O   B ALA 81  ? ? N   B LYS 85  ? ? 2.19 
# 
loop_
_pdbx_validate_rmsd_bond.id 
_pdbx_validate_rmsd_bond.PDB_model_num 
_pdbx_validate_rmsd_bond.auth_atom_id_1 
_pdbx_validate_rmsd_bond.auth_asym_id_1 
_pdbx_validate_rmsd_bond.auth_comp_id_1 
_pdbx_validate_rmsd_bond.auth_seq_id_1 
_pdbx_validate_rmsd_bond.PDB_ins_code_1 
_pdbx_validate_rmsd_bond.label_alt_id_1 
_pdbx_validate_rmsd_bond.auth_atom_id_2 
_pdbx_validate_rmsd_bond.auth_asym_id_2 
_pdbx_validate_rmsd_bond.auth_comp_id_2 
_pdbx_validate_rmsd_bond.auth_seq_id_2 
_pdbx_validate_rmsd_bond.PDB_ins_code_2 
_pdbx_validate_rmsd_bond.label_alt_id_2 
_pdbx_validate_rmsd_bond.bond_value 
_pdbx_validate_rmsd_bond.bond_target_value 
_pdbx_validate_rmsd_bond.bond_deviation 
_pdbx_validate_rmsd_bond.bond_standard_deviation 
_pdbx_validate_rmsd_bond.linker_flag 
1  1 CB    B SER 360 ? ? OG    B SER 360 ? ? 1.218 1.418 -0.200 0.013 N 
2  1 P     C DT  1   ? ? OP3   C DT  1   ? ? 1.480 1.607 -0.127 0.012 N 
3  1 "C1'" C DT  1   ? ? N1    C DT  1   ? ? 1.611 1.488 0.123  0.013 N 
4  1 C8    C DG  2   ? ? N9    C DG  2   ? ? 1.435 1.374 0.061  0.007 N 
5  1 "O3'" C DA  7   ? ? "C3'" C DA  7   ? ? 1.371 1.419 -0.048 0.006 N 
6  1 "O3'" C DT  16  ? ? "C3'" C DT  16  ? ? 1.531 1.435 0.096  0.013 N 
7  1 N9    C DA  17  ? ? C4    C DA  17  ? ? 1.428 1.374 0.054  0.006 N 
8  1 "C1'" C DT  21  ? ? N1    C DT  21  ? ? 1.566 1.488 0.078  0.013 N 
9  1 "C1'" D DT  4   ? ? N1    D DT  4   ? ? 1.587 1.488 0.099  0.013 N 
10 1 "C1'" D DC  6   ? ? N1    D DC  6   ? ? 1.579 1.488 0.091  0.013 N 
11 1 "O3'" D DA  8   ? ? "C3'" D DA  8   ? ? 1.522 1.435 0.087  0.013 N 
12 1 "O3'" D DA  15  ? ? "C3'" D DA  15  ? ? 1.373 1.419 -0.046 0.006 N 
13 1 "O3'" D DC  16  ? ? "C3'" D DC  16  ? ? 1.369 1.419 -0.050 0.006 N 
14 1 C5    D DT  18  ? ? C6    D DT  18  ? ? 1.288 1.339 -0.051 0.007 N 
15 1 C6    D DT  18  ? ? N1    D DT  18  ? ? 1.321 1.378 -0.057 0.007 N 
16 1 C2    D DT  18  ? ? O2    D DT  18  ? ? 1.273 1.220 0.053  0.008 N 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1  1 CB    A ASP 132 ? ? CG    A ASP 132 ? ? OD2 A ASP 132 ? ? 125.75 118.30 7.45   0.90 N 
2  1 CA    B CYS 34  ? ? CB    B CYS 34  ? ? SG  B CYS 34  ? ? 123.18 114.20 8.98   1.10 N 
3  1 CG    B PHE 176 ? ? CD1   B PHE 176 ? ? CE1 B PHE 176 ? ? 113.06 120.80 -7.74  1.10 N 
4  1 NE    B ARG 276 ? ? CZ    B ARG 276 ? ? NH1 B ARG 276 ? ? 124.93 120.30 4.63   0.50 N 
5  1 NE    B ARG 276 ? ? CZ    B ARG 276 ? ? NH2 B ARG 276 ? ? 115.76 120.30 -4.54  0.50 N 
6  1 CA    B LEU 335 ? ? CB    B LEU 335 ? ? CG  B LEU 335 ? ? 94.93  115.30 -20.37 2.30 N 
7  1 "O4'" C DG  2   ? ? "C1'" C DG  2   ? ? N9  C DG  2   ? ? 111.75 108.30 3.45   0.30 N 
8  1 "O4'" C DT  6   ? ? "C1'" C DT  6   ? ? N1  C DT  6   ? ? 111.05 108.30 2.75   0.30 N 
9  1 "O4'" C DG  8   ? ? "C1'" C DG  8   ? ? N9  C DG  8   ? ? 110.53 108.30 2.23   0.30 N 
10 1 "O4'" C DT  13  ? ? "C1'" C DT  13  ? ? N1  C DT  13  ? ? 111.12 108.30 2.82   0.30 N 
11 1 "O4'" C DG  15  ? ? "C1'" C DG  15  ? ? N9  C DG  15  ? ? 111.60 108.30 3.30   0.30 N 
12 1 "C3'" C DT  16  ? ? "O3'" C DT  16  ? ? P   C DA  17  ? ? 127.11 119.70 7.41   1.20 Y 
13 1 "O4'" C DT  21  ? ? "C1'" C DT  21  ? ? N1  C DT  21  ? ? 110.20 108.30 1.90   0.30 N 
14 1 "O4'" D DC  6   ? ? "C1'" D DC  6   ? ? N1  D DC  6   ? ? 110.63 108.30 2.33   0.30 N 
15 1 "O4'" D DA  7   ? ? "C1'" D DA  7   ? ? N9  D DA  7   ? ? 110.12 108.30 1.82   0.30 N 
16 1 "O4'" D DC  9   ? ? "C1'" D DC  9   ? ? N1  D DC  9   ? ? 110.43 108.30 2.13   0.30 N 
17 1 "O4'" D DC  13  ? ? "C1'" D DC  13  ? ? N1  D DC  13  ? ? 110.51 108.30 2.21   0.30 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 PHE A 14  ? ? -117.35 -169.72 
2  1 CYS A 20  ? ? -141.58 -154.09 
3  1 CYS A 151 ? ? -98.36  31.86   
4  1 LEU A 214 ? ? -64.37  4.72    
5  1 LEU A 305 ? ? -107.11 -87.84  
6  1 SER A 391 ? ? -63.04  -167.77 
7  1 LYS A 392 ? ? -117.92 66.12   
8  1 GLU A 436 ? ? -103.51 -157.86 
9  1 ILE A 445 ? ? -66.30  78.69   
10 1 ASN B 3   ? ? -131.99 -31.18  
11 1 LYS B 41  ? ? -148.62 14.70   
12 1 GLU B 55  ? ? -92.39  -66.46  
13 1 HIS B 147 ? ? -46.88  -19.55  
14 1 ILE B 157 ? ? -86.59  -72.43  
15 1 GLU B 166 ? ? -58.03  87.31   
16 1 ARG B 189 ? ? -66.58  62.57   
17 1 ASP B 191 ? ? 60.73   -124.13 
18 1 ALA B 204 ? ? 49.75   11.85   
19 1 LYS B 211 ? ? 54.59   -133.03 
20 1 GLU B 220 ? ? -36.26  -36.57  
21 1 LEU B 227 ? ? -152.45 80.71   
22 1 GLU B 231 ? ? -68.54  9.18    
23 1 LYS B 280 ? ? -155.75 22.62   
24 1 ASN B 281 ? ? 84.61   22.73   
25 1 LYS B 307 ? ? 85.78   -9.93   
26 1 LYS B 315 ? ? 53.72   -131.90 
27 1 ASP B 387 ? ? -161.72 -167.51 
28 1 MET B 414 ? ? 103.97  112.42  
# 
_pdbx_validate_peptide_omega.id               1 
_pdbx_validate_peptide_omega.PDB_model_num    1 
_pdbx_validate_peptide_omega.auth_comp_id_1   ALA 
_pdbx_validate_peptide_omega.auth_asym_id_1   B 
_pdbx_validate_peptide_omega.auth_seq_id_1    325 
_pdbx_validate_peptide_omega.PDB_ins_code_1   ? 
_pdbx_validate_peptide_omega.label_alt_id_1   ? 
_pdbx_validate_peptide_omega.auth_comp_id_2   ALA 
_pdbx_validate_peptide_omega.auth_asym_id_2   B 
_pdbx_validate_peptide_omega.auth_seq_id_2    326 
_pdbx_validate_peptide_omega.PDB_ins_code_2   ? 
_pdbx_validate_peptide_omega.label_alt_id_2   ? 
_pdbx_validate_peptide_omega.omega            149.42 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z          
2 -y,x-y,z+2/3   
3 -x+y,-x,z+1/3  
4 x-y,-y,-z+1/3  
5 -x,-x+y,-z+2/3 
6 y,x,-z         
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A LYS 170 ? A LYS 170 
2  1 Y 1 A SER 171 ? A SER 171 
3  1 Y 1 A LYS 172 ? A LYS 172 
4  1 Y 1 A ALA 173 ? A ALA 173 
5  1 Y 1 A LYS 174 ? A LYS 174 
6  1 Y 1 A SER 175 ? A SER 175 
7  1 Y 1 A PHE 176 ? A PHE 176 
8  1 Y 1 A ARG 177 ? A ARG 177 
9  1 Y 1 A TYR 178 ? A TYR 178 
10 1 Y 1 A THR 179 ? A THR 179 
11 1 Y 1 A PRO 180 ? A PRO 180 
12 1 Y 1 A THR 181 ? A THR 181 
13 1 Y 1 A LEU 182 ? A LEU 182 
14 1 Y 1 A PHE 183 ? A PHE 183 
15 1 Y 1 A GLU 184 ? A GLU 184 
16 1 Y 1 A GLU 185 ? A GLU 185 
17 1 Y 1 A PHE 186 ? A PHE 186 
18 1 Y 1 A ASN 187 ? A ASN 187 
19 1 Y 1 A LYS 188 ? A LYS 188 
20 1 Y 1 A LYS 189 ? A LYS 189 
21 1 Y 1 A LEU 190 ? A LEU 190 
22 1 Y 1 A LYS 191 ? A LYS 191 
23 1 Y 1 A GLU 192 ? A GLU 192 
24 1 Y 1 A VAL 193 ? A VAL 193 
25 1 Y 1 A GLU 194 ? A GLU 194 
26 1 Y 1 A LYS 195 ? A LYS 195 
27 1 Y 1 A GLU 196 ? A GLU 196 
28 1 Y 1 A ALA 197 ? A ALA 197 
29 1 Y 1 A LYS 198 ? A LYS 198 
30 1 Y 1 A THR 199 ? A THR 199 
31 1 Y 1 A TYR 200 ? A TYR 200 
32 1 Y 1 A ASN 201 ? A ASN 201 
33 1 Y 1 A TYR 202 ? A TYR 202 
34 1 Y 1 B SER 420 ? B SER 420 
35 1 Y 1 B GLU 421 ? B GLU 421 
36 1 Y 1 D DT  2   ? D DT  1   
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N      N  N N 1   
ALA CA     C  N S 2   
ALA C      C  N N 3   
ALA O      O  N N 4   
ALA CB     C  N N 5   
ALA OXT    O  N N 6   
ALA H      H  N N 7   
ALA H2     H  N N 8   
ALA HA     H  N N 9   
ALA HB1    H  N N 10  
ALA HB2    H  N N 11  
ALA HB3    H  N N 12  
ALA HXT    H  N N 13  
ARG N      N  N N 14  
ARG CA     C  N S 15  
ARG C      C  N N 16  
ARG O      O  N N 17  
ARG CB     C  N N 18  
ARG CG     C  N N 19  
ARG CD     C  N N 20  
ARG NE     N  N N 21  
ARG CZ     C  N N 22  
ARG NH1    N  N N 23  
ARG NH2    N  N N 24  
ARG OXT    O  N N 25  
ARG H      H  N N 26  
ARG H2     H  N N 27  
ARG HA     H  N N 28  
ARG HB2    H  N N 29  
ARG HB3    H  N N 30  
ARG HG2    H  N N 31  
ARG HG3    H  N N 32  
ARG HD2    H  N N 33  
ARG HD3    H  N N 34  
ARG HE     H  N N 35  
ARG HH11   H  N N 36  
ARG HH12   H  N N 37  
ARG HH21   H  N N 38  
ARG HH22   H  N N 39  
ARG HXT    H  N N 40  
ASN N      N  N N 41  
ASN CA     C  N S 42  
ASN C      C  N N 43  
ASN O      O  N N 44  
ASN CB     C  N N 45  
ASN CG     C  N N 46  
ASN OD1    O  N N 47  
ASN ND2    N  N N 48  
ASN OXT    O  N N 49  
ASN H      H  N N 50  
ASN H2     H  N N 51  
ASN HA     H  N N 52  
ASN HB2    H  N N 53  
ASN HB3    H  N N 54  
ASN HD21   H  N N 55  
ASN HD22   H  N N 56  
ASN HXT    H  N N 57  
ASP N      N  N N 58  
ASP CA     C  N S 59  
ASP C      C  N N 60  
ASP O      O  N N 61  
ASP CB     C  N N 62  
ASP CG     C  N N 63  
ASP OD1    O  N N 64  
ASP OD2    O  N N 65  
ASP OXT    O  N N 66  
ASP H      H  N N 67  
ASP H2     H  N N 68  
ASP HA     H  N N 69  
ASP HB2    H  N N 70  
ASP HB3    H  N N 71  
ASP HD2    H  N N 72  
ASP HXT    H  N N 73  
CYS N      N  N N 74  
CYS CA     C  N R 75  
CYS C      C  N N 76  
CYS O      O  N N 77  
CYS CB     C  N N 78  
CYS SG     S  N N 79  
CYS OXT    O  N N 80  
CYS H      H  N N 81  
CYS H2     H  N N 82  
CYS HA     H  N N 83  
CYS HB2    H  N N 84  
CYS HB3    H  N N 85  
CYS HG     H  N N 86  
CYS HXT    H  N N 87  
DA  OP3    O  N N 88  
DA  P      P  N N 89  
DA  OP1    O  N N 90  
DA  OP2    O  N N 91  
DA  "O5'"  O  N N 92  
DA  "C5'"  C  N N 93  
DA  "C4'"  C  N R 94  
DA  "O4'"  O  N N 95  
DA  "C3'"  C  N S 96  
DA  "O3'"  O  N N 97  
DA  "C2'"  C  N N 98  
DA  "C1'"  C  N R 99  
DA  N9     N  Y N 100 
DA  C8     C  Y N 101 
DA  N7     N  Y N 102 
DA  C5     C  Y N 103 
DA  C6     C  Y N 104 
DA  N6     N  N N 105 
DA  N1     N  Y N 106 
DA  C2     C  Y N 107 
DA  N3     N  Y N 108 
DA  C4     C  Y N 109 
DA  HOP3   H  N N 110 
DA  HOP2   H  N N 111 
DA  "H5'"  H  N N 112 
DA  "H5''" H  N N 113 
DA  "H4'"  H  N N 114 
DA  "H3'"  H  N N 115 
DA  "HO3'" H  N N 116 
DA  "H2'"  H  N N 117 
DA  "H2''" H  N N 118 
DA  "H1'"  H  N N 119 
DA  H8     H  N N 120 
DA  H61    H  N N 121 
DA  H62    H  N N 122 
DA  H2     H  N N 123 
DC  OP3    O  N N 124 
DC  P      P  N N 125 
DC  OP1    O  N N 126 
DC  OP2    O  N N 127 
DC  "O5'"  O  N N 128 
DC  "C5'"  C  N N 129 
DC  "C4'"  C  N R 130 
DC  "O4'"  O  N N 131 
DC  "C3'"  C  N S 132 
DC  "O3'"  O  N N 133 
DC  "C2'"  C  N N 134 
DC  "C1'"  C  N R 135 
DC  N1     N  N N 136 
DC  C2     C  N N 137 
DC  O2     O  N N 138 
DC  N3     N  N N 139 
DC  C4     C  N N 140 
DC  N4     N  N N 141 
DC  C5     C  N N 142 
DC  C6     C  N N 143 
DC  HOP3   H  N N 144 
DC  HOP2   H  N N 145 
DC  "H5'"  H  N N 146 
DC  "H5''" H  N N 147 
DC  "H4'"  H  N N 148 
DC  "H3'"  H  N N 149 
DC  "HO3'" H  N N 150 
DC  "H2'"  H  N N 151 
DC  "H2''" H  N N 152 
DC  "H1'"  H  N N 153 
DC  H41    H  N N 154 
DC  H42    H  N N 155 
DC  H5     H  N N 156 
DC  H6     H  N N 157 
DG  OP3    O  N N 158 
DG  P      P  N N 159 
DG  OP1    O  N N 160 
DG  OP2    O  N N 161 
DG  "O5'"  O  N N 162 
DG  "C5'"  C  N N 163 
DG  "C4'"  C  N R 164 
DG  "O4'"  O  N N 165 
DG  "C3'"  C  N S 166 
DG  "O3'"  O  N N 167 
DG  "C2'"  C  N N 168 
DG  "C1'"  C  N R 169 
DG  N9     N  Y N 170 
DG  C8     C  Y N 171 
DG  N7     N  Y N 172 
DG  C5     C  Y N 173 
DG  C6     C  N N 174 
DG  O6     O  N N 175 
DG  N1     N  N N 176 
DG  C2     C  N N 177 
DG  N2     N  N N 178 
DG  N3     N  N N 179 
DG  C4     C  Y N 180 
DG  HOP3   H  N N 181 
DG  HOP2   H  N N 182 
DG  "H5'"  H  N N 183 
DG  "H5''" H  N N 184 
DG  "H4'"  H  N N 185 
DG  "H3'"  H  N N 186 
DG  "HO3'" H  N N 187 
DG  "H2'"  H  N N 188 
DG  "H2''" H  N N 189 
DG  "H1'"  H  N N 190 
DG  H8     H  N N 191 
DG  H1     H  N N 192 
DG  H21    H  N N 193 
DG  H22    H  N N 194 
DT  OP3    O  N N 195 
DT  P      P  N N 196 
DT  OP1    O  N N 197 
DT  OP2    O  N N 198 
DT  "O5'"  O  N N 199 
DT  "C5'"  C  N N 200 
DT  "C4'"  C  N R 201 
DT  "O4'"  O  N N 202 
DT  "C3'"  C  N S 203 
DT  "O3'"  O  N N 204 
DT  "C2'"  C  N N 205 
DT  "C1'"  C  N R 206 
DT  N1     N  N N 207 
DT  C2     C  N N 208 
DT  O2     O  N N 209 
DT  N3     N  N N 210 
DT  C4     C  N N 211 
DT  O4     O  N N 212 
DT  C5     C  N N 213 
DT  C7     C  N N 214 
DT  C6     C  N N 215 
DT  HOP3   H  N N 216 
DT  HOP2   H  N N 217 
DT  "H5'"  H  N N 218 
DT  "H5''" H  N N 219 
DT  "H4'"  H  N N 220 
DT  "H3'"  H  N N 221 
DT  "HO3'" H  N N 222 
DT  "H2'"  H  N N 223 
DT  "H2''" H  N N 224 
DT  "H1'"  H  N N 225 
DT  H3     H  N N 226 
DT  H71    H  N N 227 
DT  H72    H  N N 228 
DT  H73    H  N N 229 
DT  H6     H  N N 230 
GLN N      N  N N 231 
GLN CA     C  N S 232 
GLN C      C  N N 233 
GLN O      O  N N 234 
GLN CB     C  N N 235 
GLN CG     C  N N 236 
GLN CD     C  N N 237 
GLN OE1    O  N N 238 
GLN NE2    N  N N 239 
GLN OXT    O  N N 240 
GLN H      H  N N 241 
GLN H2     H  N N 242 
GLN HA     H  N N 243 
GLN HB2    H  N N 244 
GLN HB3    H  N N 245 
GLN HG2    H  N N 246 
GLN HG3    H  N N 247 
GLN HE21   H  N N 248 
GLN HE22   H  N N 249 
GLN HXT    H  N N 250 
GLU N      N  N N 251 
GLU CA     C  N S 252 
GLU C      C  N N 253 
GLU O      O  N N 254 
GLU CB     C  N N 255 
GLU CG     C  N N 256 
GLU CD     C  N N 257 
GLU OE1    O  N N 258 
GLU OE2    O  N N 259 
GLU OXT    O  N N 260 
GLU H      H  N N 261 
GLU H2     H  N N 262 
GLU HA     H  N N 263 
GLU HB2    H  N N 264 
GLU HB3    H  N N 265 
GLU HG2    H  N N 266 
GLU HG3    H  N N 267 
GLU HE2    H  N N 268 
GLU HXT    H  N N 269 
GLY N      N  N N 270 
GLY CA     C  N N 271 
GLY C      C  N N 272 
GLY O      O  N N 273 
GLY OXT    O  N N 274 
GLY H      H  N N 275 
GLY H2     H  N N 276 
GLY HA2    H  N N 277 
GLY HA3    H  N N 278 
GLY HXT    H  N N 279 
HIS N      N  N N 280 
HIS CA     C  N S 281 
HIS C      C  N N 282 
HIS O      O  N N 283 
HIS CB     C  N N 284 
HIS CG     C  Y N 285 
HIS ND1    N  Y N 286 
HIS CD2    C  Y N 287 
HIS CE1    C  Y N 288 
HIS NE2    N  Y N 289 
HIS OXT    O  N N 290 
HIS H      H  N N 291 
HIS H2     H  N N 292 
HIS HA     H  N N 293 
HIS HB2    H  N N 294 
HIS HB3    H  N N 295 
HIS HD1    H  N N 296 
HIS HD2    H  N N 297 
HIS HE1    H  N N 298 
HIS HE2    H  N N 299 
HIS HXT    H  N N 300 
ILE N      N  N N 301 
ILE CA     C  N S 302 
ILE C      C  N N 303 
ILE O      O  N N 304 
ILE CB     C  N S 305 
ILE CG1    C  N N 306 
ILE CG2    C  N N 307 
ILE CD1    C  N N 308 
ILE OXT    O  N N 309 
ILE H      H  N N 310 
ILE H2     H  N N 311 
ILE HA     H  N N 312 
ILE HB     H  N N 313 
ILE HG12   H  N N 314 
ILE HG13   H  N N 315 
ILE HG21   H  N N 316 
ILE HG22   H  N N 317 
ILE HG23   H  N N 318 
ILE HD11   H  N N 319 
ILE HD12   H  N N 320 
ILE HD13   H  N N 321 
ILE HXT    H  N N 322 
LEU N      N  N N 323 
LEU CA     C  N S 324 
LEU C      C  N N 325 
LEU O      O  N N 326 
LEU CB     C  N N 327 
LEU CG     C  N N 328 
LEU CD1    C  N N 329 
LEU CD2    C  N N 330 
LEU OXT    O  N N 331 
LEU H      H  N N 332 
LEU H2     H  N N 333 
LEU HA     H  N N 334 
LEU HB2    H  N N 335 
LEU HB3    H  N N 336 
LEU HG     H  N N 337 
LEU HD11   H  N N 338 
LEU HD12   H  N N 339 
LEU HD13   H  N N 340 
LEU HD21   H  N N 341 
LEU HD22   H  N N 342 
LEU HD23   H  N N 343 
LEU HXT    H  N N 344 
LYS N      N  N N 345 
LYS CA     C  N S 346 
LYS C      C  N N 347 
LYS O      O  N N 348 
LYS CB     C  N N 349 
LYS CG     C  N N 350 
LYS CD     C  N N 351 
LYS CE     C  N N 352 
LYS NZ     N  N N 353 
LYS OXT    O  N N 354 
LYS H      H  N N 355 
LYS H2     H  N N 356 
LYS HA     H  N N 357 
LYS HB2    H  N N 358 
LYS HB3    H  N N 359 
LYS HG2    H  N N 360 
LYS HG3    H  N N 361 
LYS HD2    H  N N 362 
LYS HD3    H  N N 363 
LYS HE2    H  N N 364 
LYS HE3    H  N N 365 
LYS HZ1    H  N N 366 
LYS HZ2    H  N N 367 
LYS HZ3    H  N N 368 
LYS HXT    H  N N 369 
MET N      N  N N 370 
MET CA     C  N S 371 
MET C      C  N N 372 
MET O      O  N N 373 
MET CB     C  N N 374 
MET CG     C  N N 375 
MET SD     S  N N 376 
MET CE     C  N N 377 
MET OXT    O  N N 378 
MET H      H  N N 379 
MET H2     H  N N 380 
MET HA     H  N N 381 
MET HB2    H  N N 382 
MET HB3    H  N N 383 
MET HG2    H  N N 384 
MET HG3    H  N N 385 
MET HE1    H  N N 386 
MET HE2    H  N N 387 
MET HE3    H  N N 388 
MET HXT    H  N N 389 
MG  MG     MG N N 390 
PHE N      N  N N 391 
PHE CA     C  N S 392 
PHE C      C  N N 393 
PHE O      O  N N 394 
PHE CB     C  N N 395 
PHE CG     C  Y N 396 
PHE CD1    C  Y N 397 
PHE CD2    C  Y N 398 
PHE CE1    C  Y N 399 
PHE CE2    C  Y N 400 
PHE CZ     C  Y N 401 
PHE OXT    O  N N 402 
PHE H      H  N N 403 
PHE H2     H  N N 404 
PHE HA     H  N N 405 
PHE HB2    H  N N 406 
PHE HB3    H  N N 407 
PHE HD1    H  N N 408 
PHE HD2    H  N N 409 
PHE HE1    H  N N 410 
PHE HE2    H  N N 411 
PHE HZ     H  N N 412 
PHE HXT    H  N N 413 
PRO N      N  N N 414 
PRO CA     C  N S 415 
PRO C      C  N N 416 
PRO O      O  N N 417 
PRO CB     C  N N 418 
PRO CG     C  N N 419 
PRO CD     C  N N 420 
PRO OXT    O  N N 421 
PRO H      H  N N 422 
PRO HA     H  N N 423 
PRO HB2    H  N N 424 
PRO HB3    H  N N 425 
PRO HG2    H  N N 426 
PRO HG3    H  N N 427 
PRO HD2    H  N N 428 
PRO HD3    H  N N 429 
PRO HXT    H  N N 430 
SER N      N  N N 431 
SER CA     C  N S 432 
SER C      C  N N 433 
SER O      O  N N 434 
SER CB     C  N N 435 
SER OG     O  N N 436 
SER OXT    O  N N 437 
SER H      H  N N 438 
SER H2     H  N N 439 
SER HA     H  N N 440 
SER HB2    H  N N 441 
SER HB3    H  N N 442 
SER HG     H  N N 443 
SER HXT    H  N N 444 
THR N      N  N N 445 
THR CA     C  N S 446 
THR C      C  N N 447 
THR O      O  N N 448 
THR CB     C  N R 449 
THR OG1    O  N N 450 
THR CG2    C  N N 451 
THR OXT    O  N N 452 
THR H      H  N N 453 
THR H2     H  N N 454 
THR HA     H  N N 455 
THR HB     H  N N 456 
THR HG1    H  N N 457 
THR HG21   H  N N 458 
THR HG22   H  N N 459 
THR HG23   H  N N 460 
THR HXT    H  N N 461 
TRP N      N  N N 462 
TRP CA     C  N S 463 
TRP C      C  N N 464 
TRP O      O  N N 465 
TRP CB     C  N N 466 
TRP CG     C  Y N 467 
TRP CD1    C  Y N 468 
TRP CD2    C  Y N 469 
TRP NE1    N  Y N 470 
TRP CE2    C  Y N 471 
TRP CE3    C  Y N 472 
TRP CZ2    C  Y N 473 
TRP CZ3    C  Y N 474 
TRP CH2    C  Y N 475 
TRP OXT    O  N N 476 
TRP H      H  N N 477 
TRP H2     H  N N 478 
TRP HA     H  N N 479 
TRP HB2    H  N N 480 
TRP HB3    H  N N 481 
TRP HD1    H  N N 482 
TRP HE1    H  N N 483 
TRP HE3    H  N N 484 
TRP HZ2    H  N N 485 
TRP HZ3    H  N N 486 
TRP HH2    H  N N 487 
TRP HXT    H  N N 488 
TYR N      N  N N 489 
TYR CA     C  N S 490 
TYR C      C  N N 491 
TYR O      O  N N 492 
TYR CB     C  N N 493 
TYR CG     C  Y N 494 
TYR CD1    C  Y N 495 
TYR CD2    C  Y N 496 
TYR CE1    C  Y N 497 
TYR CE2    C  Y N 498 
TYR CZ     C  Y N 499 
TYR OH     O  N N 500 
TYR OXT    O  N N 501 
TYR H      H  N N 502 
TYR H2     H  N N 503 
TYR HA     H  N N 504 
TYR HB2    H  N N 505 
TYR HB3    H  N N 506 
TYR HD1    H  N N 507 
TYR HD2    H  N N 508 
TYR HE1    H  N N 509 
TYR HE2    H  N N 510 
TYR HH     H  N N 511 
TYR HXT    H  N N 512 
VAL N      N  N N 513 
VAL CA     C  N S 514 
VAL C      C  N N 515 
VAL O      O  N N 516 
VAL CB     C  N N 517 
VAL CG1    C  N N 518 
VAL CG2    C  N N 519 
VAL OXT    O  N N 520 
VAL H      H  N N 521 
VAL H2     H  N N 522 
VAL HA     H  N N 523 
VAL HB     H  N N 524 
VAL HG11   H  N N 525 
VAL HG12   H  N N 526 
VAL HG13   H  N N 527 
VAL HG21   H  N N 528 
VAL HG22   H  N N 529 
VAL HG23   H  N N 530 
VAL HXT    H  N N 531 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N     CA     sing N N 1   
ALA N     H      sing N N 2   
ALA N     H2     sing N N 3   
ALA CA    C      sing N N 4   
ALA CA    CB     sing N N 5   
ALA CA    HA     sing N N 6   
ALA C     O      doub N N 7   
ALA C     OXT    sing N N 8   
ALA CB    HB1    sing N N 9   
ALA CB    HB2    sing N N 10  
ALA CB    HB3    sing N N 11  
ALA OXT   HXT    sing N N 12  
ARG N     CA     sing N N 13  
ARG N     H      sing N N 14  
ARG N     H2     sing N N 15  
ARG CA    C      sing N N 16  
ARG CA    CB     sing N N 17  
ARG CA    HA     sing N N 18  
ARG C     O      doub N N 19  
ARG C     OXT    sing N N 20  
ARG CB    CG     sing N N 21  
ARG CB    HB2    sing N N 22  
ARG CB    HB3    sing N N 23  
ARG CG    CD     sing N N 24  
ARG CG    HG2    sing N N 25  
ARG CG    HG3    sing N N 26  
ARG CD    NE     sing N N 27  
ARG CD    HD2    sing N N 28  
ARG CD    HD3    sing N N 29  
ARG NE    CZ     sing N N 30  
ARG NE    HE     sing N N 31  
ARG CZ    NH1    sing N N 32  
ARG CZ    NH2    doub N N 33  
ARG NH1   HH11   sing N N 34  
ARG NH1   HH12   sing N N 35  
ARG NH2   HH21   sing N N 36  
ARG NH2   HH22   sing N N 37  
ARG OXT   HXT    sing N N 38  
ASN N     CA     sing N N 39  
ASN N     H      sing N N 40  
ASN N     H2     sing N N 41  
ASN CA    C      sing N N 42  
ASN CA    CB     sing N N 43  
ASN CA    HA     sing N N 44  
ASN C     O      doub N N 45  
ASN C     OXT    sing N N 46  
ASN CB    CG     sing N N 47  
ASN CB    HB2    sing N N 48  
ASN CB    HB3    sing N N 49  
ASN CG    OD1    doub N N 50  
ASN CG    ND2    sing N N 51  
ASN ND2   HD21   sing N N 52  
ASN ND2   HD22   sing N N 53  
ASN OXT   HXT    sing N N 54  
ASP N     CA     sing N N 55  
ASP N     H      sing N N 56  
ASP N     H2     sing N N 57  
ASP CA    C      sing N N 58  
ASP CA    CB     sing N N 59  
ASP CA    HA     sing N N 60  
ASP C     O      doub N N 61  
ASP C     OXT    sing N N 62  
ASP CB    CG     sing N N 63  
ASP CB    HB2    sing N N 64  
ASP CB    HB3    sing N N 65  
ASP CG    OD1    doub N N 66  
ASP CG    OD2    sing N N 67  
ASP OD2   HD2    sing N N 68  
ASP OXT   HXT    sing N N 69  
CYS N     CA     sing N N 70  
CYS N     H      sing N N 71  
CYS N     H2     sing N N 72  
CYS CA    C      sing N N 73  
CYS CA    CB     sing N N 74  
CYS CA    HA     sing N N 75  
CYS C     O      doub N N 76  
CYS C     OXT    sing N N 77  
CYS CB    SG     sing N N 78  
CYS CB    HB2    sing N N 79  
CYS CB    HB3    sing N N 80  
CYS SG    HG     sing N N 81  
CYS OXT   HXT    sing N N 82  
DA  OP3   P      sing N N 83  
DA  OP3   HOP3   sing N N 84  
DA  P     OP1    doub N N 85  
DA  P     OP2    sing N N 86  
DA  P     "O5'"  sing N N 87  
DA  OP2   HOP2   sing N N 88  
DA  "O5'" "C5'"  sing N N 89  
DA  "C5'" "C4'"  sing N N 90  
DA  "C5'" "H5'"  sing N N 91  
DA  "C5'" "H5''" sing N N 92  
DA  "C4'" "O4'"  sing N N 93  
DA  "C4'" "C3'"  sing N N 94  
DA  "C4'" "H4'"  sing N N 95  
DA  "O4'" "C1'"  sing N N 96  
DA  "C3'" "O3'"  sing N N 97  
DA  "C3'" "C2'"  sing N N 98  
DA  "C3'" "H3'"  sing N N 99  
DA  "O3'" "HO3'" sing N N 100 
DA  "C2'" "C1'"  sing N N 101 
DA  "C2'" "H2'"  sing N N 102 
DA  "C2'" "H2''" sing N N 103 
DA  "C1'" N9     sing N N 104 
DA  "C1'" "H1'"  sing N N 105 
DA  N9    C8     sing Y N 106 
DA  N9    C4     sing Y N 107 
DA  C8    N7     doub Y N 108 
DA  C8    H8     sing N N 109 
DA  N7    C5     sing Y N 110 
DA  C5    C6     sing Y N 111 
DA  C5    C4     doub Y N 112 
DA  C6    N6     sing N N 113 
DA  C6    N1     doub Y N 114 
DA  N6    H61    sing N N 115 
DA  N6    H62    sing N N 116 
DA  N1    C2     sing Y N 117 
DA  C2    N3     doub Y N 118 
DA  C2    H2     sing N N 119 
DA  N3    C4     sing Y N 120 
DC  OP3   P      sing N N 121 
DC  OP3   HOP3   sing N N 122 
DC  P     OP1    doub N N 123 
DC  P     OP2    sing N N 124 
DC  P     "O5'"  sing N N 125 
DC  OP2   HOP2   sing N N 126 
DC  "O5'" "C5'"  sing N N 127 
DC  "C5'" "C4'"  sing N N 128 
DC  "C5'" "H5'"  sing N N 129 
DC  "C5'" "H5''" sing N N 130 
DC  "C4'" "O4'"  sing N N 131 
DC  "C4'" "C3'"  sing N N 132 
DC  "C4'" "H4'"  sing N N 133 
DC  "O4'" "C1'"  sing N N 134 
DC  "C3'" "O3'"  sing N N 135 
DC  "C3'" "C2'"  sing N N 136 
DC  "C3'" "H3'"  sing N N 137 
DC  "O3'" "HO3'" sing N N 138 
DC  "C2'" "C1'"  sing N N 139 
DC  "C2'" "H2'"  sing N N 140 
DC  "C2'" "H2''" sing N N 141 
DC  "C1'" N1     sing N N 142 
DC  "C1'" "H1'"  sing N N 143 
DC  N1    C2     sing N N 144 
DC  N1    C6     sing N N 145 
DC  C2    O2     doub N N 146 
DC  C2    N3     sing N N 147 
DC  N3    C4     doub N N 148 
DC  C4    N4     sing N N 149 
DC  C4    C5     sing N N 150 
DC  N4    H41    sing N N 151 
DC  N4    H42    sing N N 152 
DC  C5    C6     doub N N 153 
DC  C5    H5     sing N N 154 
DC  C6    H6     sing N N 155 
DG  OP3   P      sing N N 156 
DG  OP3   HOP3   sing N N 157 
DG  P     OP1    doub N N 158 
DG  P     OP2    sing N N 159 
DG  P     "O5'"  sing N N 160 
DG  OP2   HOP2   sing N N 161 
DG  "O5'" "C5'"  sing N N 162 
DG  "C5'" "C4'"  sing N N 163 
DG  "C5'" "H5'"  sing N N 164 
DG  "C5'" "H5''" sing N N 165 
DG  "C4'" "O4'"  sing N N 166 
DG  "C4'" "C3'"  sing N N 167 
DG  "C4'" "H4'"  sing N N 168 
DG  "O4'" "C1'"  sing N N 169 
DG  "C3'" "O3'"  sing N N 170 
DG  "C3'" "C2'"  sing N N 171 
DG  "C3'" "H3'"  sing N N 172 
DG  "O3'" "HO3'" sing N N 173 
DG  "C2'" "C1'"  sing N N 174 
DG  "C2'" "H2'"  sing N N 175 
DG  "C2'" "H2''" sing N N 176 
DG  "C1'" N9     sing N N 177 
DG  "C1'" "H1'"  sing N N 178 
DG  N9    C8     sing Y N 179 
DG  N9    C4     sing Y N 180 
DG  C8    N7     doub Y N 181 
DG  C8    H8     sing N N 182 
DG  N7    C5     sing Y N 183 
DG  C5    C6     sing N N 184 
DG  C5    C4     doub Y N 185 
DG  C6    O6     doub N N 186 
DG  C6    N1     sing N N 187 
DG  N1    C2     sing N N 188 
DG  N1    H1     sing N N 189 
DG  C2    N2     sing N N 190 
DG  C2    N3     doub N N 191 
DG  N2    H21    sing N N 192 
DG  N2    H22    sing N N 193 
DG  N3    C4     sing N N 194 
DT  OP3   P      sing N N 195 
DT  OP3   HOP3   sing N N 196 
DT  P     OP1    doub N N 197 
DT  P     OP2    sing N N 198 
DT  P     "O5'"  sing N N 199 
DT  OP2   HOP2   sing N N 200 
DT  "O5'" "C5'"  sing N N 201 
DT  "C5'" "C4'"  sing N N 202 
DT  "C5'" "H5'"  sing N N 203 
DT  "C5'" "H5''" sing N N 204 
DT  "C4'" "O4'"  sing N N 205 
DT  "C4'" "C3'"  sing N N 206 
DT  "C4'" "H4'"  sing N N 207 
DT  "O4'" "C1'"  sing N N 208 
DT  "C3'" "O3'"  sing N N 209 
DT  "C3'" "C2'"  sing N N 210 
DT  "C3'" "H3'"  sing N N 211 
DT  "O3'" "HO3'" sing N N 212 
DT  "C2'" "C1'"  sing N N 213 
DT  "C2'" "H2'"  sing N N 214 
DT  "C2'" "H2''" sing N N 215 
DT  "C1'" N1     sing N N 216 
DT  "C1'" "H1'"  sing N N 217 
DT  N1    C2     sing N N 218 
DT  N1    C6     sing N N 219 
DT  C2    O2     doub N N 220 
DT  C2    N3     sing N N 221 
DT  N3    C4     sing N N 222 
DT  N3    H3     sing N N 223 
DT  C4    O4     doub N N 224 
DT  C4    C5     sing N N 225 
DT  C5    C7     sing N N 226 
DT  C5    C6     doub N N 227 
DT  C7    H71    sing N N 228 
DT  C7    H72    sing N N 229 
DT  C7    H73    sing N N 230 
DT  C6    H6     sing N N 231 
GLN N     CA     sing N N 232 
GLN N     H      sing N N 233 
GLN N     H2     sing N N 234 
GLN CA    C      sing N N 235 
GLN CA    CB     sing N N 236 
GLN CA    HA     sing N N 237 
GLN C     O      doub N N 238 
GLN C     OXT    sing N N 239 
GLN CB    CG     sing N N 240 
GLN CB    HB2    sing N N 241 
GLN CB    HB3    sing N N 242 
GLN CG    CD     sing N N 243 
GLN CG    HG2    sing N N 244 
GLN CG    HG3    sing N N 245 
GLN CD    OE1    doub N N 246 
GLN CD    NE2    sing N N 247 
GLN NE2   HE21   sing N N 248 
GLN NE2   HE22   sing N N 249 
GLN OXT   HXT    sing N N 250 
GLU N     CA     sing N N 251 
GLU N     H      sing N N 252 
GLU N     H2     sing N N 253 
GLU CA    C      sing N N 254 
GLU CA    CB     sing N N 255 
GLU CA    HA     sing N N 256 
GLU C     O      doub N N 257 
GLU C     OXT    sing N N 258 
GLU CB    CG     sing N N 259 
GLU CB    HB2    sing N N 260 
GLU CB    HB3    sing N N 261 
GLU CG    CD     sing N N 262 
GLU CG    HG2    sing N N 263 
GLU CG    HG3    sing N N 264 
GLU CD    OE1    doub N N 265 
GLU CD    OE2    sing N N 266 
GLU OE2   HE2    sing N N 267 
GLU OXT   HXT    sing N N 268 
GLY N     CA     sing N N 269 
GLY N     H      sing N N 270 
GLY N     H2     sing N N 271 
GLY CA    C      sing N N 272 
GLY CA    HA2    sing N N 273 
GLY CA    HA3    sing N N 274 
GLY C     O      doub N N 275 
GLY C     OXT    sing N N 276 
GLY OXT   HXT    sing N N 277 
HIS N     CA     sing N N 278 
HIS N     H      sing N N 279 
HIS N     H2     sing N N 280 
HIS CA    C      sing N N 281 
HIS CA    CB     sing N N 282 
HIS CA    HA     sing N N 283 
HIS C     O      doub N N 284 
HIS C     OXT    sing N N 285 
HIS CB    CG     sing N N 286 
HIS CB    HB2    sing N N 287 
HIS CB    HB3    sing N N 288 
HIS CG    ND1    sing Y N 289 
HIS CG    CD2    doub Y N 290 
HIS ND1   CE1    doub Y N 291 
HIS ND1   HD1    sing N N 292 
HIS CD2   NE2    sing Y N 293 
HIS CD2   HD2    sing N N 294 
HIS CE1   NE2    sing Y N 295 
HIS CE1   HE1    sing N N 296 
HIS NE2   HE2    sing N N 297 
HIS OXT   HXT    sing N N 298 
ILE N     CA     sing N N 299 
ILE N     H      sing N N 300 
ILE N     H2     sing N N 301 
ILE CA    C      sing N N 302 
ILE CA    CB     sing N N 303 
ILE CA    HA     sing N N 304 
ILE C     O      doub N N 305 
ILE C     OXT    sing N N 306 
ILE CB    CG1    sing N N 307 
ILE CB    CG2    sing N N 308 
ILE CB    HB     sing N N 309 
ILE CG1   CD1    sing N N 310 
ILE CG1   HG12   sing N N 311 
ILE CG1   HG13   sing N N 312 
ILE CG2   HG21   sing N N 313 
ILE CG2   HG22   sing N N 314 
ILE CG2   HG23   sing N N 315 
ILE CD1   HD11   sing N N 316 
ILE CD1   HD12   sing N N 317 
ILE CD1   HD13   sing N N 318 
ILE OXT   HXT    sing N N 319 
LEU N     CA     sing N N 320 
LEU N     H      sing N N 321 
LEU N     H2     sing N N 322 
LEU CA    C      sing N N 323 
LEU CA    CB     sing N N 324 
LEU CA    HA     sing N N 325 
LEU C     O      doub N N 326 
LEU C     OXT    sing N N 327 
LEU CB    CG     sing N N 328 
LEU CB    HB2    sing N N 329 
LEU CB    HB3    sing N N 330 
LEU CG    CD1    sing N N 331 
LEU CG    CD2    sing N N 332 
LEU CG    HG     sing N N 333 
LEU CD1   HD11   sing N N 334 
LEU CD1   HD12   sing N N 335 
LEU CD1   HD13   sing N N 336 
LEU CD2   HD21   sing N N 337 
LEU CD2   HD22   sing N N 338 
LEU CD2   HD23   sing N N 339 
LEU OXT   HXT    sing N N 340 
LYS N     CA     sing N N 341 
LYS N     H      sing N N 342 
LYS N     H2     sing N N 343 
LYS CA    C      sing N N 344 
LYS CA    CB     sing N N 345 
LYS CA    HA     sing N N 346 
LYS C     O      doub N N 347 
LYS C     OXT    sing N N 348 
LYS CB    CG     sing N N 349 
LYS CB    HB2    sing N N 350 
LYS CB    HB3    sing N N 351 
LYS CG    CD     sing N N 352 
LYS CG    HG2    sing N N 353 
LYS CG    HG3    sing N N 354 
LYS CD    CE     sing N N 355 
LYS CD    HD2    sing N N 356 
LYS CD    HD3    sing N N 357 
LYS CE    NZ     sing N N 358 
LYS CE    HE2    sing N N 359 
LYS CE    HE3    sing N N 360 
LYS NZ    HZ1    sing N N 361 
LYS NZ    HZ2    sing N N 362 
LYS NZ    HZ3    sing N N 363 
LYS OXT   HXT    sing N N 364 
MET N     CA     sing N N 365 
MET N     H      sing N N 366 
MET N     H2     sing N N 367 
MET CA    C      sing N N 368 
MET CA    CB     sing N N 369 
MET CA    HA     sing N N 370 
MET C     O      doub N N 371 
MET C     OXT    sing N N 372 
MET CB    CG     sing N N 373 
MET CB    HB2    sing N N 374 
MET CB    HB3    sing N N 375 
MET CG    SD     sing N N 376 
MET CG    HG2    sing N N 377 
MET CG    HG3    sing N N 378 
MET SD    CE     sing N N 379 
MET CE    HE1    sing N N 380 
MET CE    HE2    sing N N 381 
MET CE    HE3    sing N N 382 
MET OXT   HXT    sing N N 383 
PHE N     CA     sing N N 384 
PHE N     H      sing N N 385 
PHE N     H2     sing N N 386 
PHE CA    C      sing N N 387 
PHE CA    CB     sing N N 388 
PHE CA    HA     sing N N 389 
PHE C     O      doub N N 390 
PHE C     OXT    sing N N 391 
PHE CB    CG     sing N N 392 
PHE CB    HB2    sing N N 393 
PHE CB    HB3    sing N N 394 
PHE CG    CD1    doub Y N 395 
PHE CG    CD2    sing Y N 396 
PHE CD1   CE1    sing Y N 397 
PHE CD1   HD1    sing N N 398 
PHE CD2   CE2    doub Y N 399 
PHE CD2   HD2    sing N N 400 
PHE CE1   CZ     doub Y N 401 
PHE CE1   HE1    sing N N 402 
PHE CE2   CZ     sing Y N 403 
PHE CE2   HE2    sing N N 404 
PHE CZ    HZ     sing N N 405 
PHE OXT   HXT    sing N N 406 
PRO N     CA     sing N N 407 
PRO N     CD     sing N N 408 
PRO N     H      sing N N 409 
PRO CA    C      sing N N 410 
PRO CA    CB     sing N N 411 
PRO CA    HA     sing N N 412 
PRO C     O      doub N N 413 
PRO C     OXT    sing N N 414 
PRO CB    CG     sing N N 415 
PRO CB    HB2    sing N N 416 
PRO CB    HB3    sing N N 417 
PRO CG    CD     sing N N 418 
PRO CG    HG2    sing N N 419 
PRO CG    HG3    sing N N 420 
PRO CD    HD2    sing N N 421 
PRO CD    HD3    sing N N 422 
PRO OXT   HXT    sing N N 423 
SER N     CA     sing N N 424 
SER N     H      sing N N 425 
SER N     H2     sing N N 426 
SER CA    C      sing N N 427 
SER CA    CB     sing N N 428 
SER CA    HA     sing N N 429 
SER C     O      doub N N 430 
SER C     OXT    sing N N 431 
SER CB    OG     sing N N 432 
SER CB    HB2    sing N N 433 
SER CB    HB3    sing N N 434 
SER OG    HG     sing N N 435 
SER OXT   HXT    sing N N 436 
THR N     CA     sing N N 437 
THR N     H      sing N N 438 
THR N     H2     sing N N 439 
THR CA    C      sing N N 440 
THR CA    CB     sing N N 441 
THR CA    HA     sing N N 442 
THR C     O      doub N N 443 
THR C     OXT    sing N N 444 
THR CB    OG1    sing N N 445 
THR CB    CG2    sing N N 446 
THR CB    HB     sing N N 447 
THR OG1   HG1    sing N N 448 
THR CG2   HG21   sing N N 449 
THR CG2   HG22   sing N N 450 
THR CG2   HG23   sing N N 451 
THR OXT   HXT    sing N N 452 
TRP N     CA     sing N N 453 
TRP N     H      sing N N 454 
TRP N     H2     sing N N 455 
TRP CA    C      sing N N 456 
TRP CA    CB     sing N N 457 
TRP CA    HA     sing N N 458 
TRP C     O      doub N N 459 
TRP C     OXT    sing N N 460 
TRP CB    CG     sing N N 461 
TRP CB    HB2    sing N N 462 
TRP CB    HB3    sing N N 463 
TRP CG    CD1    doub Y N 464 
TRP CG    CD2    sing Y N 465 
TRP CD1   NE1    sing Y N 466 
TRP CD1   HD1    sing N N 467 
TRP CD2   CE2    doub Y N 468 
TRP CD2   CE3    sing Y N 469 
TRP NE1   CE2    sing Y N 470 
TRP NE1   HE1    sing N N 471 
TRP CE2   CZ2    sing Y N 472 
TRP CE3   CZ3    doub Y N 473 
TRP CE3   HE3    sing N N 474 
TRP CZ2   CH2    doub Y N 475 
TRP CZ2   HZ2    sing N N 476 
TRP CZ3   CH2    sing Y N 477 
TRP CZ3   HZ3    sing N N 478 
TRP CH2   HH2    sing N N 479 
TRP OXT   HXT    sing N N 480 
TYR N     CA     sing N N 481 
TYR N     H      sing N N 482 
TYR N     H2     sing N N 483 
TYR CA    C      sing N N 484 
TYR CA    CB     sing N N 485 
TYR CA    HA     sing N N 486 
TYR C     O      doub N N 487 
TYR C     OXT    sing N N 488 
TYR CB    CG     sing N N 489 
TYR CB    HB2    sing N N 490 
TYR CB    HB3    sing N N 491 
TYR CG    CD1    doub Y N 492 
TYR CG    CD2    sing Y N 493 
TYR CD1   CE1    sing Y N 494 
TYR CD1   HD1    sing N N 495 
TYR CD2   CE2    doub Y N 496 
TYR CD2   HD2    sing N N 497 
TYR CE1   CZ     doub Y N 498 
TYR CE1   HE1    sing N N 499 
TYR CE2   CZ     sing Y N 500 
TYR CE2   HE2    sing N N 501 
TYR CZ    OH     sing N N 502 
TYR OH    HH     sing N N 503 
TYR OXT   HXT    sing N N 504 
VAL N     CA     sing N N 505 
VAL N     H      sing N N 506 
VAL N     H2     sing N N 507 
VAL CA    C      sing N N 508 
VAL CA    CB     sing N N 509 
VAL CA    HA     sing N N 510 
VAL C     O      doub N N 511 
VAL C     OXT    sing N N 512 
VAL CB    CG1    sing N N 513 
VAL CB    CG2    sing N N 514 
VAL CB    HB     sing N N 515 
VAL CG1   HG11   sing N N 516 
VAL CG1   HG12   sing N N 517 
VAL CG1   HG13   sing N N 518 
VAL CG2   HG21   sing N N 519 
VAL CG2   HG22   sing N N 520 
VAL CG2   HG23   sing N N 521 
VAL OXT   HXT    sing N N 522 
# 
loop_
_ndb_struct_conf_na.entry_id 
_ndb_struct_conf_na.feature 
9L9W 'double helix'        
9L9W 'b-form double helix' 
# 
loop_
_ndb_struct_na_base_pair.model_number 
_ndb_struct_na_base_pair.i_label_asym_id 
_ndb_struct_na_base_pair.i_label_comp_id 
_ndb_struct_na_base_pair.i_label_seq_id 
_ndb_struct_na_base_pair.i_symmetry 
_ndb_struct_na_base_pair.j_label_asym_id 
_ndb_struct_na_base_pair.j_label_comp_id 
_ndb_struct_na_base_pair.j_label_seq_id 
_ndb_struct_na_base_pair.j_symmetry 
_ndb_struct_na_base_pair.shear 
_ndb_struct_na_base_pair.stretch 
_ndb_struct_na_base_pair.stagger 
_ndb_struct_na_base_pair.buckle 
_ndb_struct_na_base_pair.propeller 
_ndb_struct_na_base_pair.opening 
_ndb_struct_na_base_pair.pair_number 
_ndb_struct_na_base_pair.pair_name 
_ndb_struct_na_base_pair.i_auth_asym_id 
_ndb_struct_na_base_pair.i_auth_seq_id 
_ndb_struct_na_base_pair.i_PDB_ins_code 
_ndb_struct_na_base_pair.j_auth_asym_id 
_ndb_struct_na_base_pair.j_auth_seq_id 
_ndb_struct_na_base_pair.j_PDB_ins_code 
_ndb_struct_na_base_pair.hbond_type_28 
_ndb_struct_na_base_pair.hbond_type_12 
1 C DT 1  1_555 D DT 20 1_555 1.978  -0.625 1.484  31.951  6.223   176.434 1  C_DT1:DT21_D  C 1  ? D 21 ? 12 2 
1 C DG 2  1_555 D DC 18 1_555 0.112  0.717  1.759  31.437  -18.192 10.274  2  C_DG2:DC19_D  C 2  ? D 19 ? ?  1 
1 C DA 3  1_555 D DT 17 1_555 0.645  -0.362 0.674  1.421   -44.119 -4.686  3  C_DA3:DT18_D  C 3  ? D 18 ? 20 1 
1 C DG 4  1_555 D DC 16 1_555 -0.225 -0.215 -0.237 -24.599 -49.400 11.831  4  C_DG4:DC17_D  C 4  ? D 17 ? 19 1 
1 C DG 5  1_555 D DC 15 1_555 -0.317 -0.043 -0.795 -33.929 -24.640 -5.251  5  C_DG5:DC16_D  C 5  ? D 16 ? 19 1 
1 C DT 6  1_555 D DA 14 1_555 0.931  0.255  -0.402 -14.528 -18.797 4.492   6  C_DT6:DA15_D  C 6  ? D 15 ? 20 1 
1 C DA 7  1_555 D DT 13 1_555 0.600  0.235  -0.643 -32.065 -19.243 8.823   7  C_DA7:DT14_D  C 7  ? D 14 ? 20 1 
1 C DG 8  1_555 D DC 12 1_555 -0.347 -3.028 -0.733 -23.347 42.904  121.352 8  C_DG8:DC13_D  C 8  ? D 13 ? ?  ? 
1 C DT 9  1_555 D DA 11 1_555 -0.075 0.392  0.370  -20.339 -22.323 -3.301  9  C_DT9:DA12_D  C 9  ? D 12 ? 20 1 
1 C DA 10 1_555 D DT 10 1_555 0.354  0.075  -0.829 -7.149  -44.697 15.648  10 C_DA10:DT11_D C 10 ? D 11 ? 20 1 
1 C DG 11 1_555 D DC 9  1_555 -0.046 -0.711 -0.473 -4.468  -38.437 5.653   11 C_DG11:DC10_D C 11 ? D 10 ? 19 1 
1 C DG 12 1_555 D DC 8  1_555 0.422  -0.569 -0.599 -1.761  -31.628 -13.082 12 C_DG12:DC9_D  C 12 ? D 9  ? ?  1 
1 C DT 13 1_555 D DA 7  1_555 -0.847 0.451  -1.562 7.312   -40.732 3.477   13 C_DT13:DA8_D  C 13 ? D 8  ? ?  ? 
1 C DT 14 1_555 D DA 6  1_555 1.853  -0.520 -1.128 17.265  -49.468 4.381   14 C_DT14:DA7_D  C 14 ? D 7  ? 20 1 
1 C DG 15 1_555 D DC 5  1_555 -0.109 0.158  -0.250 -29.022 -20.062 -5.349  15 C_DG15:DC6_D  C 15 ? D 6  ? 19 1 
1 C DT 16 1_555 D DA 4  1_555 1.323  0.158  0.000  -5.851  -17.278 -15.627 16 C_DT16:DA5_D  C 16 ? D 5  ? 20 1 
1 C DA 17 1_555 D DT 3  1_555 -2.002 0.020  0.296  4.892   -1.514  9.466   17 C_DA17:DT4_D  C 17 ? D 4  ? ?  1 
1 C DT 18 1_555 D DA 2  1_555 1.550  -0.681 0.713  29.868  -11.700 -11.381 18 C_DT18:DA3_D  C 18 ? D 3  ? 20 1 
# 
loop_
_ndb_struct_na_base_pair_step.model_number 
_ndb_struct_na_base_pair_step.i_label_asym_id_1 
_ndb_struct_na_base_pair_step.i_label_comp_id_1 
_ndb_struct_na_base_pair_step.i_label_seq_id_1 
_ndb_struct_na_base_pair_step.i_symmetry_1 
_ndb_struct_na_base_pair_step.j_label_asym_id_1 
_ndb_struct_na_base_pair_step.j_label_comp_id_1 
_ndb_struct_na_base_pair_step.j_label_seq_id_1 
_ndb_struct_na_base_pair_step.j_symmetry_1 
_ndb_struct_na_base_pair_step.i_label_asym_id_2 
_ndb_struct_na_base_pair_step.i_label_comp_id_2 
_ndb_struct_na_base_pair_step.i_label_seq_id_2 
_ndb_struct_na_base_pair_step.i_symmetry_2 
_ndb_struct_na_base_pair_step.j_label_asym_id_2 
_ndb_struct_na_base_pair_step.j_label_comp_id_2 
_ndb_struct_na_base_pair_step.j_label_seq_id_2 
_ndb_struct_na_base_pair_step.j_symmetry_2 
_ndb_struct_na_base_pair_step.shift 
_ndb_struct_na_base_pair_step.slide 
_ndb_struct_na_base_pair_step.rise 
_ndb_struct_na_base_pair_step.tilt 
_ndb_struct_na_base_pair_step.roll 
_ndb_struct_na_base_pair_step.twist 
_ndb_struct_na_base_pair_step.x_displacement 
_ndb_struct_na_base_pair_step.y_displacement 
_ndb_struct_na_base_pair_step.helical_rise 
_ndb_struct_na_base_pair_step.inclination 
_ndb_struct_na_base_pair_step.tip 
_ndb_struct_na_base_pair_step.helical_twist 
_ndb_struct_na_base_pair_step.step_number 
_ndb_struct_na_base_pair_step.step_name 
_ndb_struct_na_base_pair_step.i_auth_asym_id_1 
_ndb_struct_na_base_pair_step.i_auth_seq_id_1 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.j_auth_asym_id_1 
_ndb_struct_na_base_pair_step.j_auth_seq_id_1 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.i_auth_asym_id_2 
_ndb_struct_na_base_pair_step.i_auth_seq_id_2 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_2 
_ndb_struct_na_base_pair_step.j_auth_asym_id_2 
_ndb_struct_na_base_pair_step.j_auth_seq_id_2 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_2 
1 C DT 1  1_555 D DT 20 1_555 C DG 2  1_555 D DC 18 1_555 0.572  0.228  2.788  -2.137   -7.009  128.840  0.171  -0.331 2.775  
-3.884  1.184   128.952  1  CC_DT1DG2:DC19DT21_DD   C 1  ? D 21 ? C 2  ? D 19 ? 
1 C DG 2  1_555 D DC 18 1_555 C DA 3  1_555 D DT 17 1_555 -0.457 2.582  4.800  8.011    -19.338 48.717   4.572  1.204  3.501  
-22.289 -9.233  52.770   2  CC_DG2DA3:DT18DC19_DD   C 2  ? D 19 ? C 3  ? D 18 ? 
1 C DA 3  1_555 D DT 17 1_555 C DG 4  1_555 D DC 16 1_555 1.288  -0.231 3.990  12.298   2.934   32.013   -0.983 0.304  4.155  
5.079   -21.290 34.358   3  CC_DA3DG4:DC17DT18_DD   C 3  ? D 18 ? C 4  ? D 17 ? 
1 C DG 4  1_555 D DC 16 1_555 C DG 5  1_555 D DC 15 1_555 -0.280 0.452  3.335  -5.388   19.600  36.669   -1.567 -0.212 3.183  
28.618  7.867   41.756   4  CC_DG4DG5:DC16DC17_DD   C 4  ? D 17 ? C 5  ? D 16 ? 
1 C DG 5  1_555 D DC 15 1_555 C DT 6  1_555 D DA 14 1_555 -0.619 0.100  2.679  -7.600   -4.474  37.620   0.613  0.152  2.719  
-6.823  11.591  38.603   5  CC_DG5DT6:DA15DC16_DD   C 5  ? D 16 ? C 6  ? D 15 ? 
1 C DT 6  1_555 D DA 14 1_555 C DA 7  1_555 D DT 13 1_555 0.065  1.171  3.663  -1.053   10.932  37.428   0.205  -0.247 3.840  
16.603  1.599   38.950   6  CC_DT6DA7:DT14DA15_DD   C 6  ? D 15 ? C 7  ? D 14 ? 
1 C DA 7  1_555 D DT 13 1_555 C DG 8  1_555 D DC 12 1_555 0.163  3.403  -1.416 155.430  -36.990 27.694   1.510  -0.996 -0.954 
-20.271 -85.176 160.364  7  CC_DA7DG8:DC13DT14_DD   C 7  ? D 14 ? C 8  ? D 13 ? 
1 C DG 8  1_555 D DC 12 1_555 C DT 9  1_555 D DA 11 1_555 0.877  2.818  -0.404 -126.033 113.273 -167.910 -1.393 0.457  -0.531 
-56.656 -63.038 -178.891 8  CC_DG8DT9:DA12DC13_DD   C 8  ? D 13 ? C 9  ? D 12 ? 
1 C DT 9  1_555 D DA 11 1_555 C DA 10 1_555 D DT 10 1_555 0.363  1.939  3.026  10.265   -4.497  36.499   3.486  0.623  2.775  
-6.981  -15.934 38.124   9  CC_DT9DA10:DT11DA12_DD  C 9  ? D 12 ? C 10 ? D 11 ? 
1 C DA 10 1_555 D DT 10 1_555 C DG 11 1_555 D DC 9  1_555 0.502  1.318  3.071  0.625    7.080   28.726   1.098  -0.852 3.304  
14.000  -1.237  29.575   10 CC_DA10DG11:DC10DT11_DD C 10 ? D 11 ? C 11 ? D 10 ? 
1 C DG 11 1_555 D DC 9  1_555 C DG 12 1_555 D DC 8  1_555 -0.866 1.817  3.225  -5.272   6.881   47.523   1.665  0.632  3.512  
8.457   6.479   48.262   11 CC_DG11DG12:DC9DC10_DD  C 11 ? D 10 ? C 12 ? D 9  ? 
1 C DG 12 1_555 D DC 8  1_555 C DT 13 1_555 D DA 7  1_555 0.559  0.163  2.567  10.323   -3.959  35.529   0.682  0.235  2.592  
-6.302  -16.432 37.157   12 CC_DG12DT13:DA8DC9_DD   C 12 ? D 9  ? C 13 ? D 8  ? 
1 C DT 13 1_555 D DA 7  1_555 C DT 14 1_555 D DA 6  1_555 -0.078 0.958  3.225  -2.409   12.743  46.067   0.140  -0.100 3.362  
15.916  3.009   47.762   13 CC_DT13DT14:DA7DA8_DD   C 13 ? D 8  ? C 14 ? D 7  ? 
1 C DT 14 1_555 D DA 6  1_555 C DG 15 1_555 D DC 5  1_555 -0.555 0.945  4.555  -13.043  7.045   31.959   0.027  -1.929 4.538  
12.021  22.255  35.148   14 CC_DT14DG15:DC6DA7_DD   C 14 ? D 7  ? C 15 ? D 6  ? 
1 C DG 15 1_555 D DC 5  1_555 C DT 16 1_555 D DA 4  1_555 -1.920 -1.020 2.593  -5.639   -8.909  35.051   -0.549 2.379  3.017  
-14.395 9.112   36.555   15 CC_DG15DT16:DA5DC6_DD   C 15 ? D 6  ? C 16 ? D 5  ? 
1 C DT 16 1_555 D DA 4  1_555 C DA 17 1_555 D DT 3  1_555 1.861  0.253  2.739  -4.044   -4.663  27.878   1.353  -4.505 2.378  
-9.530  8.265   28.540   16 CC_DT16DA17:DT4DA5_DD   C 16 ? D 5  ? C 17 ? D 4  ? 
1 C DA 17 1_555 D DT 3  1_555 C DT 18 1_555 D DA 2  1_555 -1.410 0.024  2.796  -7.049   -8.043  50.009   0.521  1.203  2.920  
-9.390  8.230   51.068   17 CC_DA17DT18:DA3DT4_DD   C 17 ? D 4  ? C 18 ? D 3  ? 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   8Z96 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 32 2 1' 
_space_group.name_Hall        
;P 32 2"
;
_space_group.IT_number        154 
_space_group.crystal_system   trigonal 
_space_group.id               1 
# 
_atom_sites.entry_id                    9L9W 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.007343 
_atom_sites.fract_transf_matrix[1][2]   0.004239 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.008479 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.005717 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C  ? ? 5.96793  ? ? ? 14.89577 ? ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
MG ? ? 11.93267 ? ? ? 13.11481 ? ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N  ? ? 6.96715  ? ? ? 11.43723 ? ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O  ? ? 7.96527  ? ? ? 9.05267  ? ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
P  ? ? 14.90797 ? ? ? 11.91318 ? ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S  ? ? 15.91112 ? ? ? 10.84690 ? ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N     . MET A 1 1   ? 75.78700  15.84000  19.27800  1.000 287.66000 ? 1   MET A N     1 
ATOM   2    C  CA    . MET A 1 1   ? 74.41000  15.71300  18.83000  1.000 289.54000 ? 1   MET A CA    1 
ATOM   3    C  C     . MET A 1 1   ? 73.63000  14.89800  19.84400  1.000 281.86000 ? 1   MET A C     1 
ATOM   4    O  O     . MET A 1 1   ? 73.63300  13.66900  19.77900  1.000 280.02000 ? 1   MET A O     1 
ATOM   5    C  CB    . MET A 1 1   ? 74.34600  15.04100  17.45400  1.000 305.00000 ? 1   MET A CB    1 
ATOM   6    C  CG    . MET A 1 1   ? 73.10200  15.36800  16.62000  1.000 313.10000 ? 1   MET A CG    1 
ATOM   7    S  SD    . MET A 1 1   ? 73.06700  14.52000  15.01800  1.000 324.28000 ? 1   MET A SD    1 
ATOM   8    C  CE    . MET A 1 1   ? 72.01200  15.61600  14.08100  1.000 292.98000 ? 1   MET A CE    1 
ATOM   9    N  N     . LYS A 1 2   ? 72.97600  15.57000  20.78900  1.000 273.72000 ? 2   LYS A N     1 
ATOM   10   C  CA    . LYS A 1 2   ? 72.15200  14.85000  21.74200  1.000 275.73000 ? 2   LYS A CA    1 
ATOM   11   C  C     . LYS A 1 2   ? 70.97400  14.19000  21.03100  1.000 272.99000 ? 2   LYS A C     1 
ATOM   12   O  O     . LYS A 1 2   ? 70.69800  14.43400  19.85200  1.000 272.10000 ? 2   LYS A O     1 
ATOM   13   C  CB    . LYS A 1 2   ? 71.66500  15.78100  22.84500  1.000 271.95000 ? 2   LYS A CB    1 
ATOM   14   C  CG    . LYS A 1 2   ? 72.66900  15.95000  23.95900  1.000 281.67000 ? 2   LYS A CG    1 
ATOM   15   C  CD    . LYS A 1 2   ? 72.82200  14.67400  24.75900  1.000 288.84000 ? 2   LYS A CD    1 
ATOM   16   C  CE    . LYS A 1 2   ? 73.76600  14.89900  25.92100  1.000 279.09000 ? 2   LYS A CE    1 
ATOM   17   N  NZ    . LYS A 1 2   ? 74.43500  13.63900  26.33000  1.000 280.65000 ? 2   LYS A NZ    1 
ATOM   18   N  N     . GLU A 1 3   ? 70.28400  13.32700  21.76700  1.000 283.01000 ? 3   GLU A N     1 
ATOM   19   C  CA    . GLU A 1 3   ? 69.22100  12.49400  21.22600  1.000 282.42000 ? 3   GLU A CA    1 
ATOM   20   C  C     . GLU A 1 3   ? 67.95200  12.66000  22.04900  1.000 285.61000 ? 3   GLU A C     1 
ATOM   21   O  O     . GLU A 1 3   ? 68.00400  12.68500  23.28400  1.000 289.29000 ? 3   GLU A O     1 
ATOM   22   C  CB    . GLU A 1 3   ? 69.62400  11.02600  21.22700  1.000 277.22000 ? 3   GLU A CB    1 
ATOM   23   C  CG    . GLU A 1 3   ? 68.43600  10.08500  21.14300  1.000 278.72000 ? 3   GLU A CG    1 
ATOM   24   C  CD    . GLU A 1 3   ? 68.87400  8.65600   21.04500  1.000 284.64000 ? 3   GLU A CD    1 
ATOM   25   O  OE1   . GLU A 1 3   ? 69.94900  8.42900   20.45400  1.000 285.84000 ? 3   GLU A OE1   1 
ATOM   26   O  OE2   . GLU A 1 3   ? 68.17400  7.76800   21.58100  1.000 288.95000 ? 3   GLU A OE2   1 
ATOM   27   N  N     . LEU A 1 4   ? 66.81100  12.74500  21.36600  1.000 281.63000 ? 4   LEU A N     1 
ATOM   28   C  CA    . LEU A 1 4   ? 65.51600  12.84500  22.02700  1.000 273.89000 ? 4   LEU A CA    1 
ATOM   29   C  C     . LEU A 1 4   ? 64.86200  11.48400  22.11500  1.000 272.08000 ? 4   LEU A C     1 
ATOM   30   O  O     . LEU A 1 4   ? 64.72900  10.78400  21.10800  1.000 276.24000 ? 4   LEU A O     1 
ATOM   31   C  CB    . LEU A 1 4   ? 64.56400  13.77500  21.28600  1.000 271.66000 ? 4   LEU A CB    1 
ATOM   32   C  CG    . LEU A 1 4   ? 65.00000  15.21200  21.09700  1.000 279.53000 ? 4   LEU A CG    1 
ATOM   33   C  CD1   . LEU A 1 4   ? 63.78600  16.08300  20.80000  1.000 273.39000 ? 4   LEU A CD1   1 
ATOM   34   C  CD2   . LEU A 1 4   ? 65.74100  15.69100  22.32400  1.000 288.00000 ? 4   LEU A CD2   1 
ATOM   35   N  N     . ILE A 1 5   ? 64.42000  11.12900  23.30600  1.000 272.51000 ? 5   ILE A N     1 
ATOM   36   C  CA    . ILE A 1 5   ? 63.46200  10.05100  23.38200  1.000 274.56000 ? 5   ILE A CA    1 
ATOM   37   C  C     . ILE A 1 5   ? 62.11300  10.66600  23.12900  1.000 275.75000 ? 5   ILE A C     1 
ATOM   38   O  O     . ILE A 1 5   ? 61.96800  11.89000  23.02700  1.000 272.23000 ? 5   ILE A O     1 
ATOM   39   C  CB    . ILE A 1 5   ? 63.47000  9.34200   24.73200  1.000 280.40000 ? 5   ILE A CB    1 
ATOM   40   C  CG1   . ILE A 1 5   ? 63.17600  10.38300  25.80500  1.000 296.93000 ? 5   ILE A CG1   1 
ATOM   41   C  CG2   . ILE A 1 5   ? 64.80000  8.64300   24.93300  1.000 284.63000 ? 5   ILE A CG2   1 
ATOM   42   C  CD1   . ILE A 1 5   ? 62.09800  9.99800   26.79800  1.000 298.75000 ? 5   ILE A CD1   1 
ATOM   43   N  N     . TYR A 1 6   ? 61.12300  9.81300   23.08100  1.000 274.60000 ? 6   TYR A N     1 
ATOM   44   C  CA    . TYR A 1 6   ? 59.78300  10.20700  22.72900  1.000 267.42000 ? 6   TYR A CA    1 
ATOM   45   C  C     . TYR A 1 6   ? 58.83100  9.61200   23.73100  1.000 267.43000 ? 6   TYR A C     1 
ATOM   46   O  O     . TYR A 1 6   ? 59.00400  8.47700   24.19100  1.000 270.40000 ? 6   TYR A O     1 
ATOM   47   C  CB    . TYR A 1 6   ? 59.41800  9.71800   21.36300  1.000 274.87000 ? 6   TYR A CB    1 
ATOM   48   C  CG    . TYR A 1 6   ? 57.97200  9.92400   21.00300  1.000 274.64000 ? 6   TYR A CG    1 
ATOM   49   C  CD1   . TYR A 1 6   ? 57.52300  11.16000  20.55600  1.000 272.45000 ? 6   TYR A CD1   1 
ATOM   50   C  CD2   . TYR A 1 6   ? 57.05800  8.88300   21.09300  1.000 276.08000 ? 6   TYR A CD2   1 
ATOM   51   C  CE1   . TYR A 1 6   ? 56.21000  11.35700  20.21300  1.000 271.31000 ? 6   TYR A CE1   1 
ATOM   52   C  CE2   . TYR A 1 6   ? 55.73800  9.07200   20.75000  1.000 278.42000 ? 6   TYR A CE2   1 
ATOM   53   C  CZ    . TYR A 1 6   ? 55.32000  10.30900  20.31100  1.000 277.43000 ? 6   TYR A CZ    1 
ATOM   54   O  OH    . TYR A 1 6   ? 54.00400  10.50700  19.96700  1.000 278.34000 ? 6   TYR A OH    1 
ATOM   55   N  N     . ILE A 1 7   ? 57.81100  10.37700  24.03700  1.000 271.23000 ? 7   ILE A N     1 
ATOM   56   C  CA    . ILE A 1 7   ? 56.79100  9.93100   24.95300  1.000 271.64000 ? 7   ILE A CA    1 
ATOM   57   C  C     . ILE A 1 7   ? 55.53100  9.64300   24.16300  1.000 274.86000 ? 7   ILE A C     1 
ATOM   58   O  O     . ILE A 1 7   ? 55.02500  10.50700  23.43100  1.000 274.53000 ? 7   ILE A O     1 
ATOM   59   C  CB    . ILE A 1 7   ? 56.57800  10.94400  26.07700  1.000 278.37000 ? 7   ILE A CB    1 
ATOM   60   C  CG1   . ILE A 1 7   ? 57.84700  10.93600  26.94100  1.000 283.25000 ? 7   ILE A CG1   1 
ATOM   61   C  CG2   . ILE A 1 7   ? 55.33600  10.54200  26.87800  1.000 272.93000 ? 7   ILE A CG2   1 
ATOM   62   C  CD1   . ILE A 1 7   ? 58.24400  12.31400  27.45700  1.000 288.56000 ? 7   ILE A CD1   1 
ATOM   63   N  N     . GLU A 1 8   ? 55.11100  8.37900   24.24000  1.000 284.74000 ? 8   GLU A N     1 
ATOM   64   C  CA    . GLU A 1 8   ? 53.85900  7.95200   23.64900  1.000 286.97000 ? 8   GLU A CA    1 
ATOM   65   C  C     . GLU A 1 8   ? 52.72400  8.77000   24.21900  1.000 278.09000 ? 8   GLU A C     1 
ATOM   66   O  O     . GLU A 1 8   ? 52.68000  9.06400   25.42300  1.000 280.02000 ? 8   GLU A O     1 
ATOM   67   C  CB    . GLU A 1 8   ? 53.63900  6.47200   23.91900  1.000 291.29000 ? 8   GLU A CB    1 
ATOM   68   C  CG    . GLU A 1 8   ? 54.33700  5.59100   22.91900  1.000 301.20000 ? 8   GLU A CG    1 
ATOM   69   C  CD    . GLU A 1 8   ? 53.37700  4.79300   22.06100  1.000 311.63000 ? 8   GLU A CD    1 
ATOM   70   O  OE1   . GLU A 1 8   ? 52.39100  4.27500   22.62300  1.000 313.40000 ? 8   GLU A OE1   1 
ATOM   71   O  OE2   . GLU A 1 8   ? 53.60300  4.68400   20.82800  1.000 315.40000 ? 8   GLU A OE2   1 
ATOM   72   N  N     . GLU A 1 9   ? 51.83600  9.13200   23.35100  1.000 278.58000 ? 9   GLU A N     1 
ATOM   73   C  CA    . GLU A 1 9   ? 50.77500  10.02200  23.74300  1.000 275.43000 ? 9   GLU A CA    1 
ATOM   74   C  C     . GLU A 1 9   ? 49.81800  9.32900   24.68800  1.000 270.96000 ? 9   GLU A C     1 
ATOM   75   O  O     . GLU A 1 9   ? 49.31500  8.23700   24.38200  1.000 272.43000 ? 9   GLU A O     1 
ATOM   76   C  CB    . GLU A 1 9   ? 50.04800  10.56400  22.54400  1.000 278.26000 ? 9   GLU A CB    1 
ATOM   77   C  CG    . GLU A 1 9   ? 49.06100  11.64800  22.84700  1.000 279.91000 ? 9   GLU A CG    1 
ATOM   78   C  CD    . GLU A 1 9   ? 49.67000  12.86500  23.51700  1.000 284.92000 ? 9   GLU A CD    1 
ATOM   79   O  OE1   . GLU A 1 9   ? 48.93500  13.56400  24.24600  1.000 282.41000 ? 9   GLU A OE1   1 
ATOM   80   O  OE2   . GLU A 1 9   ? 50.88000  13.13300  23.34400  1.000 290.48000 ? 9   GLU A OE2   1 
ATOM   81   N  N     . PRO A 1 10  ? 49.57700  9.91700   25.84800  1.000 272.85000 ? 10  PRO A N     1 
ATOM   82   C  CA    . PRO A 1 10  ? 48.70500  9.28600   26.82600  1.000 273.53000 ? 10  PRO A CA    1 
ATOM   83   C  C     . PRO A 1 10  ? 47.31700  9.15400   26.28100  1.000 265.95000 ? 10  PRO A C     1 
ATOM   84   O  O     . PRO A 1 10  ? 46.87800  9.92700   25.43100  1.000 267.24000 ? 10  PRO A O     1 
ATOM   85   C  CB    . PRO A 1 10  ? 48.72800  10.24500  28.01300  1.000 274.27000 ? 10  PRO A CB    1 
ATOM   86   C  CG    . PRO A 1 10  ? 49.01000  11.57100  27.35000  1.000 273.27000 ? 10  PRO A CG    1 
ATOM   87   C  CD    . PRO A 1 10  ? 49.95400  11.28900  26.24700  1.000 272.48000 ? 10  PRO A CD    1 
ATOM   88   N  N     . SER A 1 11  ? 46.66000  8.10200   26.71600  1.000 264.53000 ? 11  SER A N     1 
ATOM   89   C  CA    . SER A 1 11  ? 45.33200  7.76500   26.24000  1.000 272.30000 ? 11  SER A CA    1 
ATOM   90   C  C     . SER A 1 11  ? 44.33700  8.10000   27.33600  1.000 274.96000 ? 11  SER A C     1 
ATOM   91   O  O     . SER A 1 11  ? 44.52900  7.71100   28.49500  1.000 271.79000 ? 11  SER A O     1 
ATOM   92   C  CB    . SER A 1 11  ? 45.26100  6.28900   25.88100  1.000 274.43000 ? 11  SER A CB    1 
ATOM   93   O  OG    . SER A 1 11  ? 45.97400  5.54600   26.86500  1.000 286.69000 ? 11  SER A OG    1 
ATOM   94   N  N     . ILE A 1 12  ? 43.32500  8.85400   26.97000  1.000 288.81000 ? 12  ILE A N     1 
ATOM   95   C  CA    . ILE A 1 12  ? 42.20400  9.22000   27.83300  1.000 291.47000 ? 12  ILE A CA    1 
ATOM   96   C  C     . ILE A 1 12  ? 41.00500  8.34300   27.47500  1.000 281.34000 ? 12  ILE A C     1 
ATOM   97   O  O     . ILE A 1 12  ? 40.74800  8.08400   26.29500  1.000 280.15000 ? 12  ILE A O     1 
ATOM   98   C  CB    . ILE A 1 12  ? 41.88100  10.73900  27.73800  1.000 295.30000 ? 12  ILE A CB    1 
ATOM   99   C  CG1   . ILE A 1 12  ? 41.47300  11.20400  26.32900  1.000 285.24000 ? 12  ILE A CG1   1 
ATOM   100  C  CG2   . ILE A 1 12  ? 43.08500  11.55700  28.16500  1.000 298.96000 ? 12  ILE A CG2   1 
ATOM   101  C  CD1   . ILE A 1 12  ? 41.33200  12.75200  26.19500  1.000 280.79000 ? 12  ILE A CD1   1 
ATOM   102  N  N     . LEU A 1 13  ? 40.28700  7.85200   28.49200  1.000 282.17000 ? 13  LEU A N     1 
ATOM   103  C  CA    . LEU A 1 13  ? 39.24800  6.83400   28.30000  1.000 280.86000 ? 13  LEU A CA    1 
ATOM   104  C  C     . LEU A 1 13  ? 37.85000  7.41800   28.40800  1.000 283.41000 ? 13  LEU A C     1 
ATOM   105  O  O     . LEU A 1 13  ? 37.55400  8.16800   29.34100  1.000 285.07000 ? 13  LEU A O     1 
ATOM   106  C  CB    . LEU A 1 13  ? 39.41500  5.68000   29.29900  1.000 280.54000 ? 13  LEU A CB    1 
ATOM   107  C  CG    . LEU A 1 13  ? 38.72400  5.46600   30.66800  1.000 283.33000 ? 13  LEU A CG    1 
ATOM   108  C  CD1   . LEU A 1 13  ? 37.25300  4.98100   30.54300  1.000 278.96000 ? 13  LEU A CD1   1 
ATOM   109  C  CD2   . LEU A 1 13  ? 39.57400  4.49300   31.51000  1.000 292.62000 ? 13  LEU A CD2   1 
ATOM   110  N  N     . PHE A 1 14  ? 37.00500  7.05800   27.46300  1.000 289.18000 ? 14  PHE A N     1 
ATOM   111  C  CA    . PHE A 1 14  ? 35.64700  7.54700   27.33600  1.000 294.26000 ? 14  PHE A CA    1 
ATOM   112  C  C     . PHE A 1 14  ? 34.68500  6.39300   27.48900  1.000 295.29000 ? 14  PHE A C     1 
ATOM   113  O  O     . PHE A 1 14  ? 35.08600  5.27500   27.81900  1.000 291.34000 ? 14  PHE A O     1 
ATOM   114  C  CB    . PHE A 1 14  ? 35.44600  8.22400   25.98200  1.000 299.31000 ? 14  PHE A CB    1 
ATOM   115  C  CG    . PHE A 1 14  ? 36.55500  9.19200   25.59400  1.000 295.35000 ? 14  PHE A CG    1 
ATOM   116  C  CD1   . PHE A 1 14  ? 36.50300  10.51900  25.98800  1.000 289.84000 ? 14  PHE A CD1   1 
ATOM   117  C  CD2   . PHE A 1 14  ? 37.63800  8.77000   24.83900  1.000 293.48000 ? 14  PHE A CD2   1 
ATOM   118  C  CE1   . PHE A 1 14  ? 37.50100  11.40900  25.65100  1.000 282.45000 ? 14  PHE A CE1   1 
ATOM   119  C  CE2   . PHE A 1 14  ? 38.65400  9.64200   24.48700  1.000 288.21000 ? 14  PHE A CE2   1 
ATOM   120  C  CZ    . PHE A 1 14  ? 38.57400  10.98100  24.87600  1.000 283.58000 ? 14  PHE A CZ    1 
ATOM   121  N  N     . ALA A 1 15  ? 33.41700  6.65900   27.18400  1.000 296.52000 ? 15  ALA A N     1 
ATOM   122  C  CA    . ALA A 1 15  ? 32.36600  5.65900   27.30600  1.000 296.72000 ? 15  ALA A CA    1 
ATOM   123  C  C     . ALA A 1 15  ? 32.77500  4.30400   26.74200  1.000 302.69000 ? 15  ALA A C     1 
ATOM   124  O  O     . ALA A 1 15  ? 33.41800  4.21300   25.69300  1.000 304.38000 ? 15  ALA A O     1 
ATOM   125  C  CB    . ALA A 1 15  ? 31.11400  6.16900   26.61200  1.000 294.35000 ? 15  ALA A CB    1 
ATOM   126  N  N     . HIS A 1 16  ? 32.38400  3.25600   27.47900  1.000 304.70000 ? 16  HIS A N     1 
ATOM   127  C  CA    . HIS A 1 16  ? 32.66100  1.84600   27.19900  1.000 301.78000 ? 16  HIS A CA    1 
ATOM   128  C  C     . HIS A 1 16  ? 34.14800  1.52600   27.27700  1.000 298.01000 ? 16  HIS A C     1 
ATOM   129  O  O     . HIS A 1 16  ? 34.63500  0.68800   26.50900  1.000 289.42000 ? 16  HIS A O     1 
ATOM   130  C  CB    . HIS A 1 16  ? 32.07000  1.41700   25.84300  1.000 295.80000 ? 16  HIS A CB    1 
ATOM   131  C  CG    . HIS A 1 16  ? 30.64000  1.81900   25.68200  1.000 296.03000 ? 16  HIS A CG    1 
ATOM   132  N  ND1   . HIS A 1 16  ? 30.25900  2.92400   24.95300  1.000 300.74000 ? 16  HIS A ND1   1 
ATOM   133  C  CD2   . HIS A 1 16  ? 29.50000  1.28100   26.18100  1.000 287.75000 ? 16  HIS A CD2   1 
ATOM   134  C  CE1   . HIS A 1 16  ? 28.94400  3.03900   24.99100  1.000 290.91000 ? 16  HIS A CE1   1 
ATOM   135  N  NE2   . HIS A 1 16  ? 28.45900  2.05600   25.73000  1.000 292.99000 ? 16  HIS A NE2   1 
ATOM   136  N  N     . GLY A 1 17  ? 34.86800  2.18100   28.18700  1.000 297.34000 ? 17  GLY A N     1 
ATOM   137  C  CA    . GLY A 1 17  ? 36.27700  1.90500   28.37200  1.000 298.77000 ? 17  GLY A CA    1 
ATOM   138  C  C     . GLY A 1 17  ? 37.07300  1.98800   27.09000  1.000 294.46000 ? 17  GLY A C     1 
ATOM   139  O  O     . GLY A 1 17  ? 38.09700  1.31200   26.94900  1.000 297.77000 ? 17  GLY A O     1 
ATOM   140  N  N     . GLN A 1 18  ? 36.62200  2.77200   26.13500  1.000 289.06000 ? 18  GLN A N     1 
ATOM   141  C  CA    . GLN A 1 18  ? 37.36500  2.88800   24.90400  1.000 286.17000 ? 18  GLN A CA    1 
ATOM   142  C  C     . GLN A 1 18  ? 38.10100  4.20600   24.95000  1.000 287.29000 ? 18  GLN A C     1 
ATOM   143  O  O     . GLN A 1 18  ? 37.50400  5.25300   25.20000  1.000 286.45000 ? 18  GLN A O     1 
ATOM   144  C  CB    . GLN A 1 18  ? 36.45400  2.71600   23.69600  1.000 290.71000 ? 18  GLN A CB    1 
ATOM   145  C  CG    . GLN A 1 18  ? 36.45000  1.23900   23.30700  1.000 295.20000 ? 18  GLN A CG    1 
ATOM   146  C  CD    . GLN A 1 18  ? 37.85400  0.72700   23.03500  1.000 298.23000 ? 18  GLN A CD    1 
ATOM   147  O  OE1   . GLN A 1 18  ? 38.59900  1.32100   22.21900  1.000 303.31000 ? 18  GLN A OE1   1 
ATOM   148  N  NE2   . GLN A 1 18  ? 38.24600  -0.35600  23.71300  1.000 296.03000 ? 18  GLN A NE2   1 
ATOM   149  N  N     . LYS A 1 19  ? 39.40500  4.12700   24.77900  1.000 283.35000 ? 19  LYS A N     1 
ATOM   150  C  CA    . LYS A 1 19  ? 40.29800  5.24900   24.95000  1.000 280.78000 ? 19  LYS A CA    1 
ATOM   151  C  C     . LYS A 1 19  ? 40.94400  5.58500   23.61200  1.000 284.29000 ? 19  LYS A C     1 
ATOM   152  O  O     . LYS A 1 19  ? 41.31900  4.70300   22.84000  1.000 290.32000 ? 19  LYS A O     1 
ATOM   153  C  CB    . LYS A 1 19  ? 41.35600  4.94000   26.00100  1.000 279.98000 ? 19  LYS A CB    1 
ATOM   154  C  CG    . LYS A 1 19  ? 41.67200  3.46100   26.15100  1.000 285.05000 ? 19  LYS A CG    1 
ATOM   155  C  CD    . LYS A 1 19  ? 43.01800  3.25900   26.80700  1.000 288.34000 ? 19  LYS A CD    1 
ATOM   156  C  CE    . LYS A 1 19  ? 42.90100  2.51500   28.11300  1.000 286.82000 ? 19  LYS A CE    1 
ATOM   157  N  NZ    . LYS A 1 19  ? 43.62000  1.20800   28.05000  1.000 300.07000 ? 19  LYS A NZ    1 
ATOM   158  N  N     . CYS A 1 20  ? 41.06300  6.87500   23.33800  1.000 278.82000 ? 20  CYS A N     1 
ATOM   159  C  CA    . CYS A 1 20  ? 41.82200  7.36800   22.19900  1.000 273.93000 ? 20  CYS A CA    1 
ATOM   160  C  C     . CYS A 1 20  ? 42.53800  8.62900   22.65400  1.000 279.10000 ? 20  CYS A C     1 
ATOM   161  O  O     . CYS A 1 20  ? 42.79400  8.80100   23.85000  1.000 281.75000 ? 20  CYS A O     1 
ATOM   162  C  CB    . CYS A 1 20  ? 40.88300  7.57700   21.00900  1.000 273.54000 ? 20  CYS A CB    1 
ATOM   163  S  SG    . CYS A 1 20  ? 39.82500  9.01500   21.12500  1.000 276.48000 ? 20  CYS A SG    1 
ATOM   164  N  N     . THR A 1 21  ? 42.84500  9.52400   21.71700  1.000 283.36000 ? 21  THR A N     1 
ATOM   165  C  CA    . THR A 1 21  ? 43.72800  10.62600  22.05700  1.000 284.37000 ? 21  THR A CA    1 
ATOM   166  C  C     . THR A 1 21  ? 43.11200  12.01100  21.95800  1.000 285.64000 ? 21  THR A C     1 
ATOM   167  O  O     . THR A 1 21  ? 43.69100  12.96100  22.49900  1.000 283.67000 ? 21  THR A O     1 
ATOM   168  C  CB    . THR A 1 21  ? 44.98400  10.59700  21.17400  1.000 282.38000 ? 21  THR A CB    1 
ATOM   169  O  OG1   . THR A 1 21  ? 45.41400  9.24700   21.00700  1.000 283.53000 ? 21  THR A OG1   1 
ATOM   170  C  CG2   . THR A 1 21  ? 46.05400  11.31800  21.86100  1.000 276.39000 ? 21  THR A CG2   1 
ATOM   171  N  N     . ASP A 1 22  ? 41.98800  12.16500  21.28500  1.000 289.31000 ? 22  ASP A N     1 
ATOM   172  C  CA    . ASP A 1 22  ? 41.40000  13.49100  21.16300  1.000 281.07000 ? 22  ASP A CA    1 
ATOM   173  C  C     . ASP A 1 22  ? 40.04700  13.49800  21.84900  1.000 278.19000 ? 22  ASP A C     1 
ATOM   174  O  O     . ASP A 1 22  ? 39.12400  12.81700  21.37700  1.000 281.51000 ? 22  ASP A O     1 
ATOM   175  C  CB    . ASP A 1 22  ? 41.26100  13.89800  19.69500  1.000 276.99000 ? 22  ASP A CB    1 
ATOM   176  C  CG    . ASP A 1 22  ? 41.00000  15.36900  19.52300  1.000 275.94000 ? 22  ASP A CG    1 
ATOM   177  O  OD1   . ASP A 1 22  ? 40.04700  15.85600  20.13600  1.000 276.18000 ? 22  ASP A OD1   1 
ATOM   178  O  OD2   . ASP A 1 22  ? 41.75400  16.02900  18.78600  1.000 276.56000 ? 22  ASP A OD2   1 
ATOM   179  N  N     . PRO A 1 23  ? 39.87500  14.22300  22.95900  1.000 279.66000 ? 23  PRO A N     1 
ATOM   180  C  CA    . PRO A 1 23  ? 38.56100  14.22300  23.61300  1.000 279.56000 ? 23  PRO A CA    1 
ATOM   181  C  C     . PRO A 1 23  ? 37.45000  14.52600  22.63400  1.000 281.06000 ? 23  PRO A C     1 
ATOM   182  O  O     . PRO A 1 23  ? 36.48600  13.75800  22.52200  1.000 284.97000 ? 23  PRO A O     1 
ATOM   183  C  CB    . PRO A 1 23  ? 38.71500  15.30600  24.69100  1.000 276.10000 ? 23  PRO A CB    1 
ATOM   184  C  CG    . PRO A 1 23  ? 39.76900  16.19500  24.18300  1.000 277.76000 ? 23  PRO A CG    1 
ATOM   185  C  CD    . PRO A 1 23  ? 40.74900  15.26300  23.52500  1.000 281.03000 ? 23  PRO A CD    1 
ATOM   186  N  N     . ARG A 1 24  ? 37.59800  15.61200  21.88100  1.000 277.67000 ? 24  ARG A N     1 
ATOM   187  C  CA    . ARG A 1 24  ? 36.66200  15.92400  20.81400  1.000 280.99000 ? 24  ARG A CA    1 
ATOM   188  C  C     . ARG A 1 24  ? 36.29400  14.68000  20.01000  1.000 285.21000 ? 24  ARG A C     1 
ATOM   189  O  O     . ARG A 1 24  ? 35.11500  14.43400  19.74200  1.000 287.20000 ? 24  ARG A O     1 
ATOM   190  C  CB    . ARG A 1 24  ? 37.27000  17.01800  19.94300  1.000 280.07000 ? 24  ARG A CB    1 
ATOM   191  C  CG    . ARG A 1 24  ? 37.92600  18.08900  20.79500  1.000 280.57000 ? 24  ARG A CG    1 
ATOM   192  C  CD    . ARG A 1 24  ? 38.48100  19.19300  19.94700  1.000 284.29000 ? 24  ARG A CD    1 
ATOM   193  N  NE    . ARG A 1 24  ? 39.88800  18.94700  19.68600  1.000 290.16000 ? 24  ARG A NE    1 
ATOM   194  C  CZ    . ARG A 1 24  ? 40.70100  19.83900  19.14400  1.000 294.38000 ? 24  ARG A CZ    1 
ATOM   195  N  NH1   . ARG A 1 24  ? 40.22400  21.03600  18.79800  1.000 289.82000 ? 24  ARG A NH1   1 
ATOM   196  N  NH2   . ARG A 1 24  ? 41.97900  19.52900  18.95300  1.000 300.52000 ? 24  ARG A NH2   1 
ATOM   197  N  N     . ASP A 1 25  ? 37.27700  13.83600  19.69200  1.000 287.42000 ? 25  ASP A N     1 
ATOM   198  C  CA    . ASP A 1 25  ? 36.96100  12.63400  18.92500  1.000 289.48000 ? 25  ASP A CA    1 
ATOM   199  C  C     . ASP A 1 25  ? 36.48700  11.49400  19.80900  1.000 286.13000 ? 25  ASP A C     1 
ATOM   200  O  O     . ASP A 1 25  ? 35.68500  10.66000  19.37300  1.000 280.34000 ? 25  ASP A O     1 
ATOM   201  C  CB    . ASP A 1 25  ? 38.17400  12.19000  18.12900  1.000 293.31000 ? 25  ASP A CB    1 
ATOM   202  C  CG    . ASP A 1 25  ? 38.32800  12.96400  16.84700  1.000 302.95000 ? 25  ASP A CG    1 
ATOM   203  O  OD1   . ASP A 1 25  ? 37.61300  13.97600  16.68200  1.000 310.71000 ? 25  ASP A OD1   1 
ATOM   204  O  OD2   . ASP A 1 25  ? 39.14300  12.55200  15.99100  1.000 308.85000 ? 25  ASP A OD2   1 
ATOM   205  N  N     . GLY A 1 26  ? 36.98100  11.43400  21.04300  1.000 289.43000 ? 26  GLY A N     1 
ATOM   206  C  CA    . GLY A 1 26  ? 36.55800  10.36600  21.92800  1.000 290.61000 ? 26  GLY A CA    1 
ATOM   207  C  C     . GLY A 1 26  ? 35.10900  10.50700  22.35800  1.000 291.61000 ? 26  GLY A C     1 
ATOM   208  O  O     . GLY A 1 26  ? 34.37000  9.52000   22.44600  1.000 291.67000 ? 26  GLY A O     1 
ATOM   209  N  N     . LEU A 1 27  ? 34.68700  11.73500  22.64700  1.000 290.89000 ? 27  LEU A N     1 
ATOM   210  C  CA    . LEU A 1 27  ? 33.30300  11.97800  23.02200  1.000 287.56000 ? 27  LEU A CA    1 
ATOM   211  C  C     . LEU A 1 27  ? 32.39200  11.77200  21.83700  1.000 289.59000 ? 27  LEU A C     1 
ATOM   212  O  O     . LEU A 1 27  ? 31.33100  11.15500  21.95400  1.000 290.55000 ? 27  LEU A O     1 
ATOM   213  C  CB    . LEU A 1 27  ? 33.15600  13.39400  23.54800  1.000 278.32000 ? 27  LEU A CB    1 
ATOM   214  C  CG    . LEU A 1 27  ? 33.72200  13.51900  24.95800  1.000 286.99000 ? 27  LEU A CG    1 
ATOM   215  C  CD1   . LEU A 1 27  ? 34.82700  14.54200  24.98500  1.000 291.66000 ? 27  LEU A CD1   1 
ATOM   216  C  CD2   . LEU A 1 27  ? 32.62000  13.89800  25.91400  1.000 290.90000 ? 27  LEU A CD2   1 
ATOM   217  N  N     . ALA A 1 28  ? 32.80600  12.28600  20.68000  1.000 295.53000 ? 28  ALA A N     1 
ATOM   218  C  CA    . ALA A 1 28  ? 32.01500  12.15600  19.46200  1.000 298.90000 ? 28  ALA A CA    1 
ATOM   219  C  C     . ALA A 1 28  ? 31.83100  10.69900  19.09000  1.000 297.39000 ? 28  ALA A C     1 
ATOM   220  O  O     . ALA A 1 28  ? 30.75300  10.28100  18.64900  1.000 298.22000 ? 28  ALA A O     1 
ATOM   221  C  CB    . ALA A 1 28  ? 32.69800  12.91200  18.31700  1.000 301.05000 ? 28  ALA A CB    1 
ATOM   222  N  N     . LEU A 1 29  ? 32.87400  9.91200   19.26600  1.000 290.45000 ? 29  LEU A N     1 
ATOM   223  C  CA    . LEU A 1 29  ? 32.78000  8.52200   18.88800  1.000 288.08000 ? 29  LEU A CA    1 
ATOM   224  C  C     . LEU A 1 29  ? 31.89600  7.75200   19.84900  1.000 289.53000 ? 29  LEU A C     1 
ATOM   225  O  O     . LEU A 1 29  ? 31.00100  7.01100   19.43100  1.000 287.56000 ? 29  LEU A O     1 
ATOM   226  C  CB    . LEU A 1 29  ? 34.17600  7.94200   18.83400  1.000 284.24000 ? 29  LEU A CB    1 
ATOM   227  C  CG    . LEU A 1 29  ? 34.61900  7.95600   17.40200  1.000 283.14000 ? 29  LEU A CG    1 
ATOM   228  C  CD1   . LEU A 1 29  ? 35.70100  6.96300   17.30500  1.000 282.83000 ? 29  LEU A CD1   1 
ATOM   229  C  CD2   . LEU A 1 29  ? 33.42400  7.56000   16.55000  1.000 281.39000 ? 29  LEU A CD2   1 
ATOM   230  N  N     . PHE A 1 30  ? 32.12400  7.92900   21.13800  1.000 287.75000 ? 30  PHE A N     1 
ATOM   231  C  CA    . PHE A 1 30  ? 31.47100  7.11900   22.14900  1.000 287.12000 ? 30  PHE A CA    1 
ATOM   232  C  C     . PHE A 1 30  ? 30.69000  7.92800   23.15700  1.000 285.79000 ? 30  PHE A C     1 
ATOM   233  O  O     . PHE A 1 30  ? 29.76400  7.39300   23.77000  1.000 287.14000 ? 30  PHE A O     1 
ATOM   234  C  CB    . PHE A 1 30  ? 32.51600  6.26300   22.88400  1.000 288.58000 ? 30  PHE A CB    1 
ATOM   235  C  CG    . PHE A 1 30  ? 33.68700  5.87700   22.01300  1.000 289.09000 ? 30  PHE A CG    1 
ATOM   236  C  CD1   . PHE A 1 30  ? 33.49200  5.28100   20.76400  1.000 290.93000 ? 30  PHE A CD1   1 
ATOM   237  C  CD2   . PHE A 1 30  ? 34.97900  6.13300   22.42900  1.000 290.25000 ? 30  PHE A CD2   1 
ATOM   238  C  CE1   . PHE A 1 30  ? 34.56400  4.94700   19.96400  1.000 292.92000 ? 30  PHE A CE1   1 
ATOM   239  C  CE2   . PHE A 1 30  ? 36.05200  5.79600   21.63500  1.000 290.91000 ? 30  PHE A CE2   1 
ATOM   240  C  CZ    . PHE A 1 30  ? 35.84300  5.20900   20.40000  1.000 294.11000 ? 30  PHE A CZ    1 
ATOM   241  N  N     . GLY A 1 31  ? 31.02500  9.19300   23.33700  1.000 285.80000 ? 31  GLY A N     1 
ATOM   242  C  CA    . GLY A 1 31  ? 30.40900  9.97400   24.36800  1.000 292.31000 ? 31  GLY A CA    1 
ATOM   243  C  C     . GLY A 1 31  ? 31.23000  9.98100   25.63500  1.000 296.95000 ? 31  GLY A C     1 
ATOM   244  O  O     . GLY A 1 31  ? 32.39600  9.58000   25.65800  1.000 293.46000 ? 31  GLY A O     1 
ATOM   245  N  N     . PRO A 1 32  ? 30.59900  10.39400  26.72800  1.000 301.89000 ? 32  PRO A N     1 
ATOM   246  C  CA    . PRO A 1 32  ? 31.32500  10.72300  27.96000  1.000 302.08000 ? 32  PRO A CA    1 
ATOM   247  C  C     . PRO A 1 32  ? 31.59400  9.50400   28.83200  1.000 299.70000 ? 32  PRO A C     1 
ATOM   248  O  O     . PRO A 1 32  ? 31.00900  8.42900   28.65600  1.000 292.95000 ? 32  PRO A O     1 
ATOM   249  C  CB    . PRO A 1 32  ? 30.36500  11.68400  28.66000  1.000 303.71000 ? 32  PRO A CB    1 
ATOM   250  C  CG    . PRO A 1 32  ? 29.00200  11.20200  28.24000  1.000 308.09000 ? 32  PRO A CG    1 
ATOM   251  C  CD    . PRO A 1 32  ? 29.15200  10.63500  26.84700  1.000 307.58000 ? 32  PRO A CD    1 
ATOM   252  N  N     . LEU A 1 33  ? 32.49000  9.70600   29.80800  1.000 297.20000 ? 33  LEU A N     1 
ATOM   253  C  CA    . LEU A 1 33  ? 32.89900  8.58800   30.64800  1.000 299.17000 ? 33  LEU A CA    1 
ATOM   254  C  C     . LEU A 1 33  ? 31.71100  8.05500   31.45200  1.000 300.31000 ? 33  LEU A C     1 
ATOM   255  O  O     . LEU A 1 33  ? 31.49800  6.84100   31.52200  1.000 290.77000 ? 33  LEU A O     1 
ATOM   256  C  CB    . LEU A 1 33  ? 34.05300  9.00100   31.56600  1.000 293.92000 ? 33  LEU A CB    1 
ATOM   257  C  CG    . LEU A 1 33  ? 34.63900  7.79400   32.32300  1.000 283.55000 ? 33  LEU A CG    1 
ATOM   258  C  CD1   . LEU A 1 33  ? 36.13200  7.69300   32.12800  1.000 271.21000 ? 33  LEU A CD1   1 
ATOM   259  C  CD2   . LEU A 1 33  ? 34.32800  7.86300   33.78700  1.000 289.03000 ? 33  LEU A CD2   1 
ATOM   260  N  N     . ASN A 1 34  ? 30.92900  8.95400   32.07200  1.000 306.01000 ? 34  ASN A N     1 
ATOM   261  C  CA    . ASN A 1 34  ? 29.67400  8.64600   32.77500  1.000 299.55000 ? 34  ASN A CA    1 
ATOM   262  C  C     . ASN A 1 34  ? 28.53400  9.47300   32.17500  1.000 298.35000 ? 34  ASN A C     1 
ATOM   263  O  O     . ASN A 1 34  ? 28.38100  10.65800  32.51400  1.000 301.46000 ? 34  ASN A O     1 
ATOM   264  C  CB    . ASN A 1 34  ? 29.77600  8.89300   34.30100  1.000 292.01000 ? 34  ASN A CB    1 
ATOM   265  C  CG    . ASN A 1 34  ? 30.74400  10.02800  34.69700  1.000 290.22000 ? 34  ASN A CG    1 
ATOM   266  O  OD1   . ASN A 1 34  ? 31.03200  10.94800  33.92100  1.000 293.13000 ? 34  ASN A OD1   1 
ATOM   267  N  ND2   . ASN A 1 34  ? 31.22600  9.96700   35.93800  1.000 289.32000 ? 34  ASN A ND2   1 
ATOM   268  N  N     . GLN A 1 35  ? 27.73900  8.85700   31.28700  1.000 303.56000 ? 35  GLN A N     1 
ATOM   269  C  CA    . GLN A 1 35  ? 26.58100  9.55400   30.74500  1.000 305.65000 ? 35  GLN A CA    1 
ATOM   270  C  C     . GLN A 1 35  ? 25.65300  9.97500   31.88500  1.000 309.92000 ? 35  GLN A C     1 
ATOM   271  O  O     . GLN A 1 35  ? 25.53100  9.27200   32.90100  1.000 313.49000 ? 35  GLN A O     1 
ATOM   272  C  CB    . GLN A 1 35  ? 25.84000  8.67000   29.73000  1.000 311.59000 ? 35  GLN A CB    1 
ATOM   273  C  CG    . GLN A 1 35  ? 26.07500  8.98700   28.24200  1.000 308.81000 ? 35  GLN A CG    1 
ATOM   274  C  CD    . GLN A 1 35  ? 26.70300  7.82400   27.44500  1.000 313.26000 ? 35  GLN A CD    1 
ATOM   275  O  OE1   . GLN A 1 35  ? 27.23700  6.85600   28.00900  1.000 314.53000 ? 35  GLN A OE1   1 
ATOM   276  N  NE2   . GLN A 1 35  ? 26.64800  7.93500   26.11800  1.000 312.50000 ? 35  GLN A NE2   1 
ATOM   277  N  N     . ILE A 1 36  ? 25.02100  11.16100  31.72400  1.000 305.64000 ? 36  ILE A N     1 
ATOM   278  C  CA    . ILE A 1 36  ? 24.27100  11.80800  32.80200  1.000 310.57000 ? 36  ILE A CA    1 
ATOM   279  C  C     . ILE A 1 36  ? 22.82500  12.10000  32.39300  1.000 309.82000 ? 36  ILE A C     1 
ATOM   280  O  O     . ILE A 1 36  ? 22.49600  12.28200  31.21200  1.000 301.29000 ? 36  ILE A O     1 
ATOM   281  C  CB    . ILE A 1 36  ? 24.95800  13.12300  33.29300  1.000 313.22000 ? 36  ILE A CB    1 
ATOM   282  C  CG1   . ILE A 1 36  ? 24.75500  14.29900  32.31000  1.000 311.88000 ? 36  ILE A CG1   1 
ATOM   283  C  CG2   . ILE A 1 36  ? 26.41900  12.91500  33.58900  1.000 308.07000 ? 36  ILE A CG2   1 
ATOM   284  C  CD1   . ILE A 1 36  ? 25.47100  15.61600  32.72300  1.000 303.23000 ? 36  ILE A CD1   1 
ATOM   285  N  N     . TYR A 1 37  ? 21.95800  12.07900  33.40400  1.000 302.22000 ? 37  TYR A N     1 
ATOM   286  C  CA    . TYR A 1 37  ? 20.58800  12.53700  33.28500  1.000 305.33000 ? 37  TYR A CA    1 
ATOM   287  C  C     . TYR A 1 37  ? 20.60200  14.00700  32.86900  1.000 307.93000 ? 37  TYR A C     1 
ATOM   288  O  O     . TYR A 1 37  ? 21.51100  14.75600  33.21600  1.000 313.41000 ? 37  TYR A O     1 
ATOM   289  C  CB    . TYR A 1 37  ? 19.86800  12.33700  34.62700  1.000 316.98000 ? 37  TYR A CB    1 
ATOM   290  C  CG    . TYR A 1 37  ? 20.44700  11.17600  35.44300  1.000 322.18000 ? 37  TYR A CG    1 
ATOM   291  C  CD1   . TYR A 1 37  ? 20.59900  9.91700   34.87900  1.000 313.87000 ? 37  TYR A CD1   1 
ATOM   292  C  CD2   . TYR A 1 37  ? 20.86900  11.34500  36.76400  1.000 319.53000 ? 37  TYR A CD2   1 
ATOM   293  C  CE1   . TYR A 1 37  ? 21.13900  8.85900   35.59500  1.000 312.60000 ? 37  TYR A CE1   1 
ATOM   294  C  CE2   . TYR A 1 37  ? 21.41300  10.27700  37.49700  1.000 314.08000 ? 37  TYR A CE2   1 
ATOM   295  C  CZ    . TYR A 1 37  ? 21.54300  9.04000   36.90000  1.000 312.70000 ? 37  TYR A CZ    1 
ATOM   296  O  OH    . TYR A 1 37  ? 22.07900  7.99400   37.61700  1.000 306.40000 ? 37  TYR A OH    1 
ATOM   297  N  N     . GLY A 1 38  ? 19.62100  14.42000  32.07400  1.000 315.48000 ? 38  GLY A N     1 
ATOM   298  C  CA    . GLY A 1 38  ? 19.79000  15.63800  31.28700  1.000 311.91000 ? 38  GLY A CA    1 
ATOM   299  C  C     . GLY A 1 38  ? 20.10800  16.85800  32.13500  1.000 319.18000 ? 38  GLY A C     1 
ATOM   300  O  O     . GLY A 1 38  ? 19.58600  17.03000  33.23900  1.000 331.08000 ? 38  GLY A O     1 
ATOM   301  N  N     . ILE A 1 39  ? 20.95700  17.73500  31.59400  1.000 310.73000 ? 39  ILE A N     1 
ATOM   302  C  CA    . ILE A 1 39  ? 21.28900  18.95400  32.30700  1.000 311.36000 ? 39  ILE A CA    1 
ATOM   303  C  C     . ILE A 1 39  ? 20.05800  19.83900  32.38400  1.000 309.81000 ? 39  ILE A C     1 
ATOM   304  O  O     . ILE A 1 39  ? 19.38100  20.09400  31.37900  1.000 304.38000 ? 39  ILE A O     1 
ATOM   305  C  CB    . ILE A 1 39  ? 22.45000  19.68700  31.62900  1.000 304.42000 ? 39  ILE A CB    1 
ATOM   306  C  CG1   . ILE A 1 39  ? 23.64400  18.76200  31.42100  1.000 303.34000 ? 39  ILE A CG1   1 
ATOM   307  C  CG2   . ILE A 1 39  ? 22.84700  20.87800  32.49400  1.000 306.66000 ? 39  ILE A CG2   1 
ATOM   308  C  CD1   . ILE A 1 39  ? 24.81900  19.37500  30.64200  1.000 294.04000 ? 39  ILE A CD1   1 
ATOM   309  N  N     . LYS A 1 40  ? 19.69700  20.21000  33.60400  1.000 318.65000 ? 40  LYS A N     1 
ATOM   310  C  CA    . LYS A 1 40  ? 18.79400  21.31900  33.86400  1.000 317.90000 ? 40  LYS A CA    1 
ATOM   311  C  C     . LYS A 1 40  ? 19.68600  22.54300  33.90500  1.000 313.13000 ? 40  LYS A C     1 
ATOM   312  O  O     . LYS A 1 40  ? 20.69200  22.56000  34.62400  1.000 317.39000 ? 40  LYS A O     1 
ATOM   313  C  CB    . LYS A 1 40  ? 18.02300  21.14600  35.18100  1.000 322.68000 ? 40  LYS A CB    1 
ATOM   314  C  CG    . LYS A 1 40  ? 16.52300  21.51600  35.10200  1.000 322.36000 ? 40  LYS A CG    1 
ATOM   315  C  CD    . LYS A 1 40  ? 15.58000  20.43700  35.67200  1.000 318.49000 ? 40  LYS A CD    1 
ATOM   316  C  CE    . LYS A 1 40  ? 14.12200  20.80300  35.34700  1.000 315.29000 ? 40  LYS A CE    1 
ATOM   317  N  NZ    . LYS A 1 40  ? 13.27000  21.18200  36.50100  1.000 327.19000 ? 40  LYS A NZ    1 
ATOM   318  N  N     . SER A 1 41  ? 19.33400  23.54500  33.12800  1.000 300.66000 ? 41  SER A N     1 
ATOM   319  C  CA    . SER A 1 41  ? 20.18800  24.69400  32.95300  1.000 296.82000 ? 41  SER A CA    1 
ATOM   320  C  C     . SER A 1 41  ? 19.44700  25.91000  33.47700  1.000 292.49000 ? 41  SER A C     1 
ATOM   321  O  O     . SER A 1 41  ? 18.27900  26.12100  33.13600  1.000 290.54000 ? 41  SER A O     1 
ATOM   322  C  CB    . SER A 1 41  ? 20.53800  24.81600  31.48100  1.000 291.71000 ? 41  SER A CB    1 
ATOM   323  O  OG    . SER A 1 41  ? 19.50700  24.22300  30.71300  1.000 294.97000 ? 41  SER A OG    1 
ATOM   324  N  N     . GLY A 1 42  ? 20.11200  26.69700  34.31400  1.000 296.00000 ? 42  GLY A N     1 
ATOM   325  C  CA    . GLY A 1 42  ? 19.50300  27.88000  34.86100  1.000 295.84000 ? 42  GLY A CA    1 
ATOM   326  C  C     . GLY A 1 42  ? 20.21800  29.11100  34.34600  1.000 295.25000 ? 42  GLY A C     1 
ATOM   327  O  O     . GLY A 1 42  ? 21.42600  29.10100  34.13400  1.000 294.46000 ? 42  GLY A O     1 
ATOM   328  N  N     . VAL A 1 43  ? 19.46500  30.18100  34.16800  1.000 295.92000 ? 43  VAL A N     1 
ATOM   329  C  CA    . VAL A 1 43  ? 20.02900  31.35500  33.53100  1.000 301.08000 ? 43  VAL A CA    1 
ATOM   330  C  C     . VAL A 1 43  ? 19.91600  32.55200  34.46300  1.000 302.33000 ? 43  VAL A C     1 
ATOM   331  O  O     . VAL A 1 43  ? 18.91800  32.70000  35.18200  1.000 304.09000 ? 43  VAL A O     1 
ATOM   332  C  CB    . VAL A 1 43  ? 19.35700  31.63200  32.17400  1.000 307.90000 ? 43  VAL A CB    1 
ATOM   333  C  CG1   . VAL A 1 43  ? 20.14800  32.71400  31.47200  1.000 308.32000 ? 43  VAL A CG1   1 
ATOM   334  C  CG2   . VAL A 1 43  ? 19.22200  30.30900  31.29300  1.000 317.03000 ? 43  VAL A CG2   1 
ATOM   335  N  N     . VAL A 1 44  ? 20.97500  33.37300  34.47800  1.000 301.67000 ? 44  VAL A N     1 
ATOM   336  C  CA    . VAL A 1 44  ? 21.06100  34.59100  35.27400  1.000 302.69000 ? 44  VAL A CA    1 
ATOM   337  C  C     . VAL A 1 44  ? 21.50400  35.72300  34.37100  1.000 293.12000 ? 44  VAL A C     1 
ATOM   338  O  O     . VAL A 1 44  ? 22.65700  36.16700  34.43500  1.000 290.21000 ? 44  VAL A O     1 
ATOM   339  C  CB    . VAL A 1 44  ? 22.03700  34.43500  36.45300  1.000 310.20000 ? 44  VAL A CB    1 
ATOM   340  C  CG1   . VAL A 1 44  ? 21.73200  35.47000  37.53900  1.000 307.50000 ? 44  VAL A CG1   1 
ATOM   341  C  CG2   . VAL A 1 44  ? 21.98500  33.04800  37.01700  1.000 313.48000 ? 44  VAL A CG2   1 
ATOM   342  N  N     . GLY A 1 45  ? 20.59800  36.16900  33.51000  1.000 298.32000 ? 45  GLY A N     1 
ATOM   343  C  CA    . GLY A 1 45  ? 20.91200  37.24900  32.59800  1.000 307.60000 ? 45  GLY A CA    1 
ATOM   344  C  C     . GLY A 1 45  ? 19.68800  38.03000  32.17700  1.000 310.63000 ? 45  GLY A C     1 
ATOM   345  O  O     . GLY A 1 45  ? 18.58600  37.84900  32.69300  1.000 309.73000 ? 45  GLY A O     1 
ATOM   346  N  N     . THR A 1 46  ? 19.92200  38.95500  31.25400  1.000 310.47000 ? 46  THR A N     1 
ATOM   347  C  CA    . THR A 1 46  ? 18.87100  39.80700  30.71400  1.000 306.42000 ? 46  THR A CA    1 
ATOM   348  C  C     . THR A 1 46  ? 17.85200  38.95700  29.97800  1.000 304.36000 ? 46  THR A C     1 
ATOM   349  O  O     . THR A 1 46  ? 18.15000  37.83300  29.54000  1.000 302.47000 ? 46  THR A O     1 
ATOM   350  C  CB    . THR A 1 46  ? 19.44400  40.86200  29.75600  1.000 301.78000 ? 46  THR A CB    1 
ATOM   351  O  OG1   . THR A 1 46  ? 20.43700  40.28400  28.90100  1.000 302.29000 ? 46  THR A OG1   1 
ATOM   352  C  CG2   . THR A 1 46  ? 20.05900  42.02600  30.50400  1.000 303.98000 ? 46  THR A CG2   1 
ATOM   353  N  N     . GLN A 1 47  ? 16.62400  39.48100  29.87600  1.000 302.07000 ? 47  GLN A N     1 
ATOM   354  C  CA    . GLN A 1 47  ? 15.66200  38.81500  29.02600  1.000 302.38000 ? 47  GLN A CA    1 
ATOM   355  C  C     . GLN A 1 47  ? 16.28000  38.50700  27.68000  1.000 306.39000 ? 47  GLN A C     1 
ATOM   356  O  O     . GLN A 1 47  ? 15.95700  37.47200  27.08200  1.000 309.92000 ? 47  GLN A O     1 
ATOM   357  C  CB    . GLN A 1 47  ? 14.42200  39.69000  28.87500  1.000 305.07000 ? 47  GLN A CB    1 
ATOM   358  C  CG    . GLN A 1 47  ? 13.25000  39.21800  29.74800  1.000 310.43000 ? 47  GLN A CG    1 
ATOM   359  C  CD    . GLN A 1 47  ? 11.87600  39.32300  29.08000  1.000 313.76000 ? 47  GLN A CD    1 
ATOM   360  O  OE1   . GLN A 1 47  ? 11.40700  40.41300  28.73600  1.000 315.24000 ? 47  GLN A OE1   1 
ATOM   361  N  NE2   . GLN A 1 47  ? 11.22100  38.17000  28.90200  1.000 310.71000 ? 47  GLN A NE2   1 
ATOM   362  N  N     . LYS A 1 48  ? 17.17600  39.38400  27.19300  1.000 304.16000 ? 48  LYS A N     1 
ATOM   363  C  CA    . LYS A 1 48  ? 17.89100  39.08400  25.95400  1.000 303.67000 ? 48  LYS A CA    1 
ATOM   364  C  C     . LYS A 1 48  ? 18.91700  37.97100  26.15300  1.000 296.48000 ? 48  LYS A C     1 
ATOM   365  O  O     . LYS A 1 48  ? 19.07100  37.09600  25.28200  1.000 292.10000 ? 48  LYS A O     1 
ATOM   366  C  CB    . LYS A 1 48  ? 18.56200  40.34700  25.43200  1.000 303.31000 ? 48  LYS A CB    1 
ATOM   367  C  CG    . LYS A 1 48  ? 19.58900  40.10600  24.33900  1.000 298.07000 ? 48  LYS A CG    1 
ATOM   368  C  CD    . LYS A 1 48  ? 19.43000  41.11900  23.22200  1.000 297.07000 ? 48  LYS A CD    1 
ATOM   369  C  CE    . LYS A 1 48  ? 20.74800  41.43900  22.55200  1.000 304.30000 ? 48  LYS A CE    1 
ATOM   370  N  NZ    . LYS A 1 48  ? 21.11800  42.86500  22.73300  1.000 310.99000 ? 48  LYS A NZ    1 
ATOM   371  N  N     . GLY A 1 49  ? 19.58600  37.96600  27.32100  1.000 305.10000 ? 49  GLY A N     1 
ATOM   372  C  CA    . GLY A 1 49  ? 20.47800  36.87200  27.66200  1.000 301.48000 ? 49  GLY A CA    1 
ATOM   373  C  C     . GLY A 1 49  ? 19.83800  35.49800  27.46900  1.000 301.55000 ? 49  GLY A C     1 
ATOM   374  O  O     . GLY A 1 49  ? 20.55600  34.52900  27.15800  1.000 299.86000 ? 49  GLY A O     1 
ATOM   375  N  N     . LEU A 1 50  ? 18.48800  35.37500  27.66600  1.000 304.77000 ? 50  LEU A N     1 
ATOM   376  C  CA    . LEU A 1 50  ? 17.85700  34.06600  27.48800  1.000 300.95000 ? 50  LEU A CA    1 
ATOM   377  C  C     . LEU A 1 50  ? 17.79900  33.70600  26.00700  1.000 302.10000 ? 50  LEU A C     1 
ATOM   378  O  O     . LEU A 1 50  ? 18.13300  32.57800  25.60300  1.000 299.70000 ? 50  LEU A O     1 
ATOM   379  C  CB    . LEU A 1 50  ? 16.47700  34.08900  28.10000  1.000 294.60000 ? 50  LEU A CB    1 
ATOM   380  C  CG    . LEU A 1 50  ? 16.16900  33.08800  28.99300  1.000 293.95000 ? 50  LEU A CG    1 
ATOM   381  C  CD1   . LEU A 1 50  ? 16.68100  31.73300  28.39600  1.000 292.53000 ? 50  LEU A CD1   1 
ATOM   382  C  CD2   . LEU A 1 50  ? 16.69100  33.46300  30.57800  1.000 305.04000 ? 50  LEU A CD2   1 
ATOM   383  N  N     . GLN A 1 51  ? 17.28700  34.62500  25.19200  1.000 306.27000 ? 51  GLN A N     1 
ATOM   384  C  CA    . GLN A 1 51  ? 17.07700  34.30800  23.79700  1.000 308.64000 ? 51  GLN A CA    1 
ATOM   385  C  C     . GLN A 1 51  ? 18.38800  33.94100  23.16400  1.000 305.56000 ? 51  GLN A C     1 
ATOM   386  O  O     . GLN A 1 51  ? 18.46200  33.01600  22.35100  1.000 305.34000 ? 51  GLN A O     1 
ATOM   387  C  CB    . GLN A 1 51  ? 16.45700  35.50500  23.11600  1.000 309.82000 ? 51  GLN A CB    1 
ATOM   388  C  CG    . GLN A 1 51  ? 15.42500  35.07100  22.17300  1.000 314.44000 ? 51  GLN A CG    1 
ATOM   389  C  CD    . GLN A 1 51  ? 14.93200  36.19800  21.38300  1.000 338.37000 ? 51  GLN A CD    1 
ATOM   390  O  OE1   . GLN A 1 51  ? 15.17300  37.35800  21.70600  1.000 353.65000 ? 51  GLN A OE1   1 
ATOM   391  N  NE2   . GLN A 1 51  ? 14.23800  35.88300  20.31600  1.000 326.29000 ? 51  GLN A NE2   1 
ATOM   392  N  N     . ILE A 1 52  ? 19.44900  34.61600  23.59700  1.000 305.25000 ? 52  ILE A N     1 
ATOM   393  C  CA    . ILE A 1 52  ? 20.78300  34.25000  23.14700  1.000 303.29000 ? 52  ILE A CA    1 
ATOM   394  C  C     . ILE A 1 52  ? 21.15000  32.87700  23.68700  1.000 306.84000 ? 52  ILE A C     1 
ATOM   395  O  O     . ILE A 1 52  ? 21.61400  31.99300  22.94900  1.000 303.67000 ? 52  ILE A O     1 
ATOM   396  C  CB    . ILE A 1 52  ? 21.80700  35.31600  23.57800  1.000 297.68000 ? 52  ILE A CB    1 
ATOM   397  C  CG1   . ILE A 1 52  ? 21.35600  36.68500  23.08500  1.000 294.86000 ? 52  ILE A CG1   1 
ATOM   398  C  CG2   . ILE A 1 52  ? 23.18400  34.95500  23.08400  1.000 298.09000 ? 52  ILE A CG2   1 
ATOM   399  C  CD1   . ILE A 1 52  ? 22.43200  37.74500  23.08700  1.000 305.82000 ? 52  ILE A CD1   1 
ATOM   400  N  N     . PHE A 1 53  ? 20.93500  32.67200  24.99000  1.000 306.85000 ? 53  PHE A N     1 
ATOM   401  C  CA    . PHE A 1 53  ? 21.26800  31.38300  25.56800  1.000 301.21000 ? 53  PHE A CA    1 
ATOM   402  C  C     . PHE A 1 53  ? 20.37500  30.30000  24.98900  1.000 295.91000 ? 53  PHE A C     1 
ATOM   403  O  O     . PHE A 1 53  ? 20.82100  29.15600  24.78400  1.000 293.94000 ? 53  PHE A O     1 
ATOM   404  C  CB    . PHE A 1 53  ? 21.17600  31.43100  27.09200  1.000 291.53000 ? 53  PHE A CB    1 
ATOM   405  C  CG    . PHE A 1 53  ? 21.59200  30.16900  27.71400  1.000 287.93000 ? 53  PHE A CG    1 
ATOM   406  C  CD1   . PHE A 1 53  ? 20.65000  29.24700  28.10700  1.000 292.50000 ? 53  PHE A CD1   1 
ATOM   407  C  CD2   . PHE A 1 53  ? 22.92700  29.85600  27.83900  1.000 287.23000 ? 53  PHE A CD2   1 
ATOM   408  C  CE1   . PHE A 1 53  ? 21.03000  28.06300  28.66200  1.000 302.96000 ? 53  PHE A CE1   1 
ATOM   409  C  CE2   . PHE A 1 53  ? 23.31300  28.66800  28.39100  1.000 293.63000 ? 53  PHE A CE2   1 
ATOM   410  C  CZ    . PHE A 1 53  ? 22.36700  27.76600  28.80500  1.000 300.35000 ? 53  PHE A CZ    1 
ATOM   411  N  N     . LYS A 1 54  ? 19.11900  30.65200  24.68300  1.000 302.04000 ? 54  LYS A N     1 
ATOM   412  C  CA    . LYS A 1 54  ? 18.30900  29.71800  23.91400  1.000 301.91000 ? 54  LYS A CA    1 
ATOM   413  C  C     . LYS A 1 54  ? 18.82000  29.57900  22.49400  1.000 304.37000 ? 54  LYS A C     1 
ATOM   414  O  O     . LYS A 1 54  ? 18.66400  28.51200  21.88400  1.000 302.99000 ? 54  LYS A O     1 
ATOM   415  C  CB    . LYS A 1 54  ? 16.84600  30.15100  23.89600  1.000 295.76000 ? 54  LYS A CB    1 
ATOM   416  C  CG    . LYS A 1 54  ? 16.10100  29.73100  25.12000  1.000 289.57000 ? 54  LYS A CG    1 
ATOM   417  C  CD    . LYS A 1 54  ? 14.62400  30.10000  25.06400  1.000 292.16000 ? 54  LYS A CD    1 
ATOM   418  C  CE    . LYS A 1 54  ? 14.24600  30.89900  26.29000  1.000 296.31000 ? 54  LYS A CE    1 
ATOM   419  N  NZ    . LYS A 1 54  ? 12.85300  31.36200  26.34100  1.000 301.07000 ? 54  LYS A NZ    1 
ATOM   420  N  N     . SER A 1 55  ? 19.42800  30.63300  21.94400  1.000 301.34000 ? 55  SER A N     1 
ATOM   421  C  CA    . SER A 1 55  ? 19.95300  30.49200  20.59800  1.000 293.38000 ? 55  SER A CA    1 
ATOM   422  C  C     . SER A 1 55  ? 20.98700  29.39400  20.56400  1.000 289.38000 ? 55  SER A C     1 
ATOM   423  O  O     . SER A 1 55  ? 21.02200  28.58100  19.63700  1.000 291.80000 ? 55  SER A O     1 
ATOM   424  C  CB    . SER A 1 55  ? 20.56000  31.80400  20.10800  1.000 292.74000 ? 55  SER A CB    1 
ATOM   425  O  OG    . SER A 1 55  ? 19.54800  32.71800  19.76600  1.000 298.75000 ? 55  SER A OG    1 
ATOM   426  N  N     . TYR A 1 56  ? 21.82900  29.34600  21.58000  1.000 289.64000 ? 56  TYR A N     1 
ATOM   427  C  CA    . TYR A 1 56  ? 22.93000  28.40600  21.53400  1.000 283.53000 ? 56  TYR A CA    1 
ATOM   428  C  C     . TYR A 1 56  ? 22.44500  26.97400  21.75900  1.000 287.69000 ? 56  TYR A C     1 
ATOM   429  O  O     . TYR A 1 56  ? 22.75800  26.07700  20.95900  1.000 287.49000 ? 56  TYR A O     1 
ATOM   430  C  CB    . TYR A 1 56  ? 23.99500  28.84900  22.52400  1.000 286.39000 ? 56  TYR A CB    1 
ATOM   431  C  CG    . TYR A 1 56  ? 25.36700  28.56800  22.02000  1.000 281.05000 ? 56  TYR A CG    1 
ATOM   432  C  CD1   . TYR A 1 56  ? 26.20500  27.73200  22.72200  1.000 290.69000 ? 56  TYR A CD1   1 
ATOM   433  C  CD2   . TYR A 1 56  ? 25.80900  29.09000  20.82300  1.000 286.56000 ? 56  TYR A CD2   1 
ATOM   434  C  CE1   . TYR A 1 56  ? 27.46700  27.43700  22.27100  1.000 282.43000 ? 56  TYR A CE1   1 
ATOM   435  C  CE2   . TYR A 1 56  ? 27.08300  28.79800  20.35200  1.000 288.02000 ? 56  TYR A CE2   1 
ATOM   436  C  CZ    . TYR A 1 56  ? 27.90900  27.96400  21.08600  1.000 282.14000 ? 56  TYR A CZ    1 
ATOM   437  O  OH    . TYR A 1 56  ? 29.18300  27.63400  20.67300  1.000 281.10000 ? 56  TYR A OH    1 
ATOM   438  N  N     . LEU A 1 57  ? 21.64100  26.75700  22.81500  1.000 290.42000 ? 57  LEU A N     1 
ATOM   439  C  CA    . LEU A 1 57  ? 21.07600  25.43700  23.08200  1.000 291.33000 ? 57  LEU A CA    1 
ATOM   440  C  C     . LEU A 1 57  ? 20.37200  24.88900  21.85300  1.000 288.86000 ? 57  LEU A C     1 
ATOM   441  O  O     . LEU A 1 57  ? 20.61300  23.74200  21.45100  1.000 292.43000 ? 57  LEU A O     1 
ATOM   442  C  CB    . LEU A 1 57  ? 20.11100  25.49500  24.29100  1.000 290.40000 ? 57  LEU A CB    1 
ATOM   443  C  CG    . LEU A 1 57  ? 20.65800  25.71700  25.71500  1.000 288.43000 ? 57  LEU A CG    1 
ATOM   444  C  CD1   . LEU A 1 57  ? 19.65500  25.45700  26.85400  1.000 295.87000 ? 57  LEU A CD1   1 
ATOM   445  C  CD2   . LEU A 1 57  ? 21.90800  24.89000  25.88800  1.000 285.70000 ? 57  LEU A CD2   1 
ATOM   446  N  N     . ASP A 1 58  ? 19.49300  25.68300  21.24100  1.000 292.37000 ? 58  ASP A N     1 
ATOM   447  C  CA    . ASP A 1 58  ? 19.01900  25.25300  19.93800  1.000 289.28000 ? 58  ASP A CA    1 
ATOM   448  C  C     . ASP A 1 58  ? 20.18400  25.09000  18.97400  1.000 286.86000 ? 58  ASP A C     1 
ATOM   449  O  O     . ASP A 1 58  ? 20.24000  24.10700  18.22600  1.000 283.96000 ? 58  ASP A O     1 
ATOM   450  C  CB    . ASP A 1 58  ? 17.97800  26.22300  19.40000  1.000 290.23000 ? 58  ASP A CB    1 
ATOM   451  C  CG    . ASP A 1 58  ? 16.91700  26.52200  20.42300  1.000 296.44000 ? 58  ASP A CG    1 
ATOM   452  O  OD1   . ASP A 1 58  ? 17.22300  26.35100  21.60600  1.000 304.81000 ? 58  ASP A OD1   1 
ATOM   453  O  OD2   . ASP A 1 58  ? 15.78800  26.92700  20.06800  1.000 304.27000 ? 58  ASP A OD2   1 
ATOM   454  N  N     . LYS A 1 59  ? 21.16700  25.99100  19.02100  1.000 281.82000 ? 59  LYS A N     1 
ATOM   455  C  CA    . LYS A 1 59  ? 22.20100  25.91900  17.99400  1.000 281.37000 ? 59  LYS A CA    1 
ATOM   456  C  C     . LYS A 1 59  ? 23.02500  24.64600  18.09800  1.000 282.74000 ? 59  LYS A C     1 
ATOM   457  O  O     . LYS A 1 59  ? 23.28800  23.99900  17.07900  1.000 286.12000 ? 59  LYS A O     1 
ATOM   458  C  CB    . LYS A 1 59  ? 23.11500  27.13100  18.02400  1.000 289.42000 ? 59  LYS A CB    1 
ATOM   459  C  CG    . LYS A 1 59  ? 23.48700  27.54200  16.58800  1.000 297.32000 ? 59  LYS A CG    1 
ATOM   460  C  CD    . LYS A 1 59  ? 24.89700  28.09700  16.46000  1.000 301.68000 ? 59  LYS A CD    1 
ATOM   461  C  CE    . LYS A 1 59  ? 24.90000  29.62100  16.52600  1.000 305.01000 ? 59  LYS A CE    1 
ATOM   462  N  NZ    . LYS A 1 59  ? 26.26400  30.21100  16.44800  1.000 311.82000 ? 59  LYS A NZ    1 
ATOM   463  N  N     . ILE A 1 60  ? 23.43000  24.25300  19.30600  1.000 290.28000 ? 60  ILE A N     1 
ATOM   464  C  CA    . ILE A 1 60  ? 24.38000  23.14400  19.43300  1.000 291.97000 ? 60  ILE A CA    1 
ATOM   465  C  C     . ILE A 1 60  ? 23.71700  21.77400  19.43900  1.000 295.01000 ? 60  ILE A C     1 
ATOM   466  O  O     . ILE A 1 60  ? 24.43300  20.76200  19.60400  1.000 295.83000 ? 60  ILE A O     1 
ATOM   467  C  CB    . ILE A 1 60  ? 25.22200  23.30000  20.72300  1.000 287.44000 ? 60  ILE A CB    1 
ATOM   468  C  CG1   . ILE A 1 60  ? 24.28000  23.10300  21.91000  1.000 294.41000 ? 60  ILE A CG1   1 
ATOM   469  C  CG2   . ILE A 1 60  ? 25.97500  24.62800  20.70300  1.000 282.71000 ? 60  ILE A CG2   1 
ATOM   470  C  CD1   . ILE A 1 60  ? 24.97700  23.11100  23.21600  1.000 296.72000 ? 60  ILE A CD1   1 
ATOM   471  N  N     . GLN A 1 61  ? 22.38600  21.71800  19.30100  1.000 295.11000 ? 61  GLN A N     1 
ATOM   472  C  CA    . GLN A 1 61  ? 21.74200  20.44000  19.05200  1.000 296.83000 ? 61  GLN A CA    1 
ATOM   473  C  C     . GLN A 1 61  ? 22.11000  19.89200  17.67300  1.000 295.44000 ? 61  GLN A C     1 
ATOM   474  O  O     . GLN A 1 61  ? 22.37200  18.69100  17.52500  1.000 291.20000 ? 61  GLN A O     1 
ATOM   475  C  CB    . GLN A 1 61  ? 20.22700  20.60700  19.18700  1.000 300.97000 ? 61  GLN A CB    1 
ATOM   476  C  CG    . GLN A 1 61  ? 19.72100  20.72300  20.61500  1.000 303.58000 ? 61  GLN A CG    1 
ATOM   477  C  CD    . GLN A 1 61  ? 19.32200  19.38100  21.17900  1.000 325.56000 ? 61  GLN A CD    1 
ATOM   478  O  OE1   . GLN A 1 61  ? 20.12200  18.71000  21.83600  1.000 323.19000 ? 61  GLN A OE1   1 
ATOM   479  N  NE2   . GLN A 1 61  ? 18.08400  18.97000  20.91100  1.000 335.43000 ? 61  GLN A NE2   1 
ATOM   480  N  N     . LYS A 1 62  ? 22.13900  20.76200  16.65600  1.000 296.05000 ? 62  LYS A N     1 
ATOM   481  C  CA    . LYS A 1 62  ? 22.59000  20.51400  15.29500  1.000 292.15000 ? 62  LYS A CA    1 
ATOM   482  C  C     . LYS A 1 62  ? 24.11400  20.58200  15.23200  1.000 287.77000 ? 62  LYS A C     1 
ATOM   483  O  O     . LYS A 1 62  ? 24.74300  21.26500  16.03800  1.000 293.71000 ? 62  LYS A O     1 
ATOM   484  C  CB    . LYS A 1 62  ? 22.00600  21.55600  14.34100  1.000 298.13000 ? 62  LYS A CB    1 
ATOM   485  C  CG    . LYS A 1 62  ? 20.48200  21.67200  14.31300  1.000 305.78000 ? 62  LYS A CG    1 
ATOM   486  C  CD    . LYS A 1 62  ? 20.00500  22.67700  13.23700  1.000 315.37000 ? 62  LYS A CD    1 
ATOM   487  C  CE    . LYS A 1 62  ? 18.49000  22.71000  13.12100  1.000 308.06000 ? 62  LYS A CE    1 
ATOM   488  N  NZ    . LYS A 1 62  ? 18.03200  23.51900  11.97400  1.000 319.54000 ? 62  LYS A NZ    1 
ATOM   489  N  N     . PRO A 1 63  ? 24.73400  19.90400  14.27800  1.000 279.38000 ? 63  PRO A N     1 
ATOM   490  C  CA    . PRO A 1 63  ? 26.18900  19.99600  14.15900  1.000 277.13000 ? 63  PRO A CA    1 
ATOM   491  C  C     . PRO A 1 63  ? 26.61700  21.38500  13.72000  1.000 276.38000 ? 63  PRO A C     1 
ATOM   492  O  O     . PRO A 1 63  ? 25.90000  22.09300  13.01000  1.000 285.29000 ? 63  PRO A O     1 
ATOM   493  C  CB    . PRO A 1 63  ? 26.52100  18.95100  13.09300  1.000 276.17000 ? 63  PRO A CB    1 
ATOM   494  C  CG    . PRO A 1 63  ? 25.29600  18.90300  12.24100  1.000 279.22000 ? 63  PRO A CG    1 
ATOM   495  C  CD    . PRO A 1 63  ? 24.14600  19.09300  13.20300  1.000 279.23000 ? 63  PRO A CD    1 
ATOM   496  N  N     . ILE A 1 64  ? 27.80900  21.77100  14.15500  1.000 279.08000 ? 64  ILE A N     1 
ATOM   497  C  CA    . ILE A 1 64  ? 28.40500  23.05800  13.82800  1.000 278.91000 ? 64  ILE A CA    1 
ATOM   498  C  C     . ILE A 1 64  ? 29.87300  22.80200  13.54300  1.000 279.41000 ? 64  ILE A C     1 
ATOM   499  O  O     . ILE A 1 64  ? 30.55900  22.13800  14.32500  1.000 280.09000 ? 64  ILE A O     1 
ATOM   500  C  CB    . ILE A 1 64  ? 28.23700  24.10100  14.95700  1.000 281.94000 ? 64  ILE A CB    1 
ATOM   501  C  CG1   . ILE A 1 64  ? 28.46500  23.50700  16.36000  1.000 280.74000 ? 64  ILE A CG1   1 
ATOM   502  C  CG2   . ILE A 1 64  ? 26.87500  24.77100  14.87600  1.000 289.09000 ? 64  ILE A CG2   1 
ATOM   503  C  CD1   . ILE A 1 64  ? 28.04600  24.49000  17.45500  1.000 282.66000 ? 64  ILE A CD1   1 
ATOM   504  N  N     . TYR A 1 65  ? 30.36200  23.32500  12.44100  1.000 284.44000 ? 65  TYR A N     1 
ATOM   505  C  CA    . TYR A 1 65  ? 31.64700  22.88300  11.93500  1.000 282.61000 ? 65  TYR A CA    1 
ATOM   506  C  C     . TYR A 1 65  ? 32.71500  23.94100  12.11000  1.000 285.46000 ? 65  TYR A C     1 
ATOM   507  O  O     . TYR A 1 65  ? 32.44700  25.14800  12.09400  1.000 285.31000 ? 65  TYR A O     1 
ATOM   508  C  CB    . TYR A 1 65  ? 31.58400  22.51300  10.46000  1.000 292.86000 ? 65  TYR A CB    1 
ATOM   509  C  CG    . TYR A 1 65  ? 30.68400  21.35700  10.06500  1.000 297.26000 ? 65  TYR A CG    1 
ATOM   510  C  CD1   . TYR A 1 65  ? 31.13100  20.42700  9.13100   1.000 304.26000 ? 65  TYR A CD1   1 
ATOM   511  C  CD2   . TYR A 1 65  ? 29.38500  21.21000  10.57900  1.000 287.58000 ? 65  TYR A CD2   1 
ATOM   512  C  CE1   . TYR A 1 65  ? 30.34500  19.39600  8.71600   1.000 297.53000 ? 65  TYR A CE1   1 
ATOM   513  C  CE2   . TYR A 1 65  ? 28.57900  20.15000  10.16500  1.000 285.92000 ? 65  TYR A CE2   1 
ATOM   514  C  CZ    . TYR A 1 65  ? 29.07600  19.25500  9.23200   1.000 290.51000 ? 65  TYR A CZ    1 
ATOM   515  O  OH    . TYR A 1 65  ? 28.31500  18.20600  8.79400   1.000 282.64000 ? 65  TYR A OH    1 
ATOM   516  N  N     . ASN A 1 66  ? 33.93500  23.47200  12.22700  1.000 285.92000 ? 66  ASN A N     1 
ATOM   517  C  CA    . ASN A 1 66  ? 35.00300  24.42900  12.29400  1.000 296.02000 ? 66  ASN A CA    1 
ATOM   518  C  C     . ASN A 1 66  ? 35.45700  24.77100  10.87600  1.000 301.39000 ? 66  ASN A C     1 
ATOM   519  O  O     . ASN A 1 66  ? 34.91300  24.28700  9.88500   1.000 298.19000 ? 66  ASN A O     1 
ATOM   520  C  CB    . ASN A 1 66  ? 36.11600  23.86700  13.16900  1.000 304.73000 ? 66  ASN A CB    1 
ATOM   521  C  CG    . ASN A 1 66  ? 35.64700  23.59700  14.61500  1.000 303.37000 ? 66  ASN A CG    1 
ATOM   522  O  OD1   . ASN A 1 66  ? 36.47100  23.28900  15.48700  1.000 307.40000 ? 66  ASN A OD1   1 
ATOM   523  N  ND2   . ASN A 1 66  ? 34.34100  23.70200  14.86700  1.000 296.71000 ? 66  ASN A ND2   1 
ATOM   524  N  N     . HIS A 1 67  ? 36.45000  25.64800  10.77800  1.000 310.57000 ? 67  HIS A N     1 
ATOM   525  C  CA    . HIS A 1 67  ? 36.96800  26.04800  9.47100   1.000 315.32000 ? 67  HIS A CA    1 
ATOM   526  C  C     . HIS A 1 67  ? 37.52900  24.84700  8.72200   1.000 304.99000 ? 67  HIS A C     1 
ATOM   527  O  O     . HIS A 1 67  ? 37.18500  24.57900  7.56100   1.000 291.72000 ? 67  HIS A O     1 
ATOM   528  C  CB    . HIS A 1 67  ? 38.04600  27.09000  9.67200   1.000 319.34000 ? 67  HIS A CB    1 
ATOM   529  C  CG    . HIS A 1 67  ? 38.72900  27.51100  8.41000   1.000 314.65000 ? 67  HIS A CG    1 
ATOM   530  N  ND1   . HIS A 1 67  ? 38.04800  28.06900  7.35100   1.000 316.79000 ? 67  HIS A ND1   1 
ATOM   531  C  CD2   . HIS A 1 67  ? 40.02900  27.45600  8.03400   1.000 306.28000 ? 67  HIS A CD2   1 
ATOM   532  C  CE1   . HIS A 1 67  ? 38.89500  28.34700  6.37800   1.000 307.76000 ? 67  HIS A CE1   1 
ATOM   533  N  NE2   . HIS A 1 67  ? 40.10400  27.98500  6.76700   1.000 312.27000 ? 67  HIS A NE2   1 
ATOM   534  N  N     . ASN A 1 68  ? 38.41100  24.11800  9.38600   1.000 305.19000 ? 68  ASN A N     1 
ATOM   535  C  CA    . ASN A 1 68  ? 38.99300  22.88600  8.88200   1.000 297.78000 ? 68  ASN A CA    1 
ATOM   536  C  C     . ASN A 1 68  ? 38.89400  21.89000  10.02900  1.000 302.21000 ? 68  ASN A C     1 
ATOM   537  O  O     . ASN A 1 68  ? 39.36300  22.16600  11.14100  1.000 308.46000 ? 68  ASN A O     1 
ATOM   538  C  CB    . ASN A 1 68  ? 40.41100  23.20200  8.35000   1.000 286.91000 ? 68  ASN A CB    1 
ATOM   539  C  CG    . ASN A 1 68  ? 41.47300  22.19100  8.65800   1.000 287.83000 ? 68  ASN A CG    1 
ATOM   540  O  OD1   . ASN A 1 68  ? 41.73700  21.87300  9.81800   1.000 303.98000 ? 68  ASN A OD1   1 
ATOM   541  N  ND2   . ASN A 1 68  ? 42.18600  21.77100  7.62000   1.000 278.70000 ? 68  ASN A ND2   1 
ATOM   542  N  N     . ASN A 1 69  ? 38.20400  20.77100  9.78200   1.000 297.50000 ? 69  ASN A N     1 
ATOM   543  C  CA    . ASN A 1 69  ? 37.67600  19.92900  10.85300  1.000 288.47000 ? 69  ASN A CA    1 
ATOM   544  C  C     . ASN A 1 69  ? 38.59200  18.75200  11.16800  1.000 284.85000 ? 69  ASN A C     1 
ATOM   545  O  O     . ASN A 1 69  ? 38.20600  17.83300  11.90400  1.000 283.92000 ? 69  ASN A O     1 
ATOM   546  C  CB    . ASN A 1 69  ? 36.25700  19.47200  10.50100  1.000 286.75000 ? 69  ASN A CB    1 
ATOM   547  C  CG    . ASN A 1 69  ? 35.38400  20.64000  10.05000  1.000 293.38000 ? 69  ASN A CG    1 
ATOM   548  O  OD1   . ASN A 1 69  ? 34.61900  21.20400  10.84100  1.000 292.59000 ? 69  ASN A OD1   1 
ATOM   549  N  ND2   . ASN A 1 69  ? 35.51000  21.02000  8.77900   1.000 294.28000 ? 69  ASN A ND2   1 
ATOM   550  N  N     . ILE A 1 70  ? 39.79300  18.79000  10.60700  1.000 290.69000 ? 70  ILE A N     1 
ATOM   551  C  CA    . ILE A 1 70  ? 40.90900  17.93800  10.97200  1.000 296.50000 ? 70  ILE A CA    1 
ATOM   552  C  C     . ILE A 1 70  ? 41.70700  18.53800  12.12800  1.000 296.05000 ? 70  ILE A C     1 
ATOM   553  O  O     . ILE A 1 70  ? 41.83800  17.92500  13.19700  1.000 280.71000 ? 70  ILE A O     1 
ATOM   554  C  CB    . ILE A 1 70  ? 41.80700  17.71700  9.72700   1.000 299.93000 ? 70  ILE A CB    1 
ATOM   555  C  CG1   . ILE A 1 70  ? 41.11700  16.82300  8.65500   1.000 284.55000 ? 70  ILE A CG1   1 
ATOM   556  C  CG2   . ILE A 1 70  ? 43.19800  17.21500  10.12600  1.000 304.17000 ? 70  ILE A CG2   1 
ATOM   557  C  CD1   . ILE A 1 70  ? 41.63700  16.97400  7.19500   1.000 287.72000 ? 70  ILE A CD1   1 
ATOM   558  N  N     . THR A 1 71  ? 42.24400  19.75700  11.91500  1.000 299.33000 ? 71  THR A N     1 
ATOM   559  C  CA    . THR A 1 71  ? 42.97900  20.44900  12.97800  1.000 298.38000 ? 71  THR A CA    1 
ATOM   560  C  C     . THR A 1 71  ? 42.06700  20.76900  14.14400  1.000 296.94000 ? 71  THR A C     1 
ATOM   561  O  O     . THR A 1 71  ? 42.52300  20.92700  15.28000  1.000 294.47000 ? 71  THR A O     1 
ATOM   562  C  CB    . THR A 1 71  ? 43.59800  21.75600  12.47400  1.000 303.03000 ? 71  THR A CB    1 
ATOM   563  O  OG1   . THR A 1 71  ? 42.57300  22.65600  12.03100  1.000 310.81000 ? 71  THR A OG1   1 
ATOM   564  C  CG2   . THR A 1 71  ? 44.53700  21.50300  11.33200  1.000 296.35000 ? 71  THR A CG2   1 
ATOM   565  N  N     . ARG A 1 72  ? 40.77200  20.88700  13.87200  1.000 298.40000 ? 72  ARG A N     1 
ATOM   566  C  CA    . ARG A 1 72  ? 39.76400  21.05400  14.90800  1.000 294.04000 ? 72  ARG A CA    1 
ATOM   567  C  C     . ARG A 1 72  ? 38.59200  20.13900  14.53400  1.000 286.45000 ? 72  ARG A C     1 
ATOM   568  O  O     . ARG A 1 72  ? 37.87800  20.43700  13.56900  1.000 284.58000 ? 72  ARG A O     1 
ATOM   569  C  CB    . ARG A 1 72  ? 39.29800  22.50200  15.07000  1.000 296.12000 ? 72  ARG A CB    1 
ATOM   570  C  CG    . ARG A 1 72  ? 40.40100  23.53800  15.42600  1.000 290.14000 ? 72  ARG A CG    1 
ATOM   571  C  CD    . ARG A 1 72  ? 39.81600  24.92900  15.73300  1.000 294.54000 ? 72  ARG A CD    1 
ATOM   572  N  NE    . ARG A 1 72  ? 40.84700  25.96800  15.76200  1.000 297.61000 ? 72  ARG A NE    1 
ATOM   573  C  CZ    . ARG A 1 72  ? 41.67600  26.15300  16.78500  1.000 295.91000 ? 72  ARG A CZ    1 
ATOM   574  N  NH1   . ARG A 1 72  ? 41.57700  25.36700  17.84200  1.000 287.94000 ? 72  ARG A NH1   1 
ATOM   575  N  NH2   . ARG A 1 72  ? 42.60400  27.10700  16.76300  1.000 309.46000 ? 72  ARG A NH2   1 
ATOM   576  N  N     . PRO A 1 73  ? 38.38100  19.03700  15.24600  1.000 282.04000 ? 73  PRO A N     1 
ATOM   577  C  CA    . PRO A 1 73  ? 37.20300  18.18800  14.99000  1.000 279.51000 ? 73  PRO A CA    1 
ATOM   578  C  C     . PRO A 1 73  ? 35.88200  18.92600  15.11900  1.000 281.75000 ? 73  PRO A C     1 
ATOM   579  O  O     . PRO A 1 73  ? 35.68200  19.74900  16.01200  1.000 288.25000 ? 73  PRO A O     1 
ATOM   580  C  CB    . PRO A 1 73  ? 37.30500  17.12500  16.07000  1.000 285.80000 ? 73  PRO A CB    1 
ATOM   581  C  CG    . PRO A 1 73  ? 38.65800  17.24100  16.65800  1.000 285.87000 ? 73  PRO A CG    1 
ATOM   582  C  CD    . PRO A 1 73  ? 39.17800  18.59900  16.39800  1.000 287.31000 ? 73  PRO A CD    1 
ATOM   583  N  N     . MET A 1 74  ? 34.96000  18.59200  14.22500  1.000 272.97000 ? 74  MET A N     1 
ATOM   584  C  CA    . MET A 1 74  ? 33.62500  19.14300  14.33400  1.000 276.76000 ? 74  MET A CA    1 
ATOM   585  C  C     . MET A 1 74  ? 32.92300  18.67600  15.60400  1.000 279.69000 ? 74  MET A C     1 
ATOM   586  O  O     . MET A 1 74  ? 33.33600  17.73700  16.29000  1.000 272.20000 ? 74  MET A O     1 
ATOM   587  C  CB    . MET A 1 74  ? 32.79200  18.70200  13.16300  1.000 275.46000 ? 74  MET A CB    1 
ATOM   588  C  CG    . MET A 1 74  ? 32.77100  17.27600  13.11900  1.000 274.56000 ? 74  MET A CG    1 
ATOM   589  S  SD    . MET A 1 74  ? 31.18200  16.74700  12.53800  1.000 280.12000 ? 74  MET A SD    1 
ATOM   590  C  CE    . MET A 1 74  ? 30.03500  18.17500  13.02200  1.000 278.02000 ? 74  MET A CE    1 
ATOM   591  N  N     . PHE A 1 75  ? 31.82000  19.35900  15.88300  1.000 285.57000 ? 75  PHE A N     1 
ATOM   592  C  CA    . PHE A 1 75  ? 30.96600  19.14500  17.04500  1.000 285.79000 ? 75  PHE A CA    1 
ATOM   593  C  C     . PHE A 1 75  ? 29.67300  18.55000  16.51500  1.000 284.51000 ? 75  PHE A C     1 
ATOM   594  O  O     . PHE A 1 75  ? 28.81900  19.27500  15.98700  1.000 289.78000 ? 75  PHE A O     1 
ATOM   595  C  CB    . PHE A 1 75  ? 30.71200  20.46700  17.79000  1.000 286.41000 ? 75  PHE A CB    1 
ATOM   596  C  CG    . PHE A 1 75  ? 29.95500  20.34000  19.10700  1.000 280.54000 ? 75  PHE A CG    1 
ATOM   597  C  CD1   . PHE A 1 75  ? 28.56500  20.27600  19.13600  1.000 273.84000 ? 75  PHE A CD1   1 
ATOM   598  C  CD2   . PHE A 1 75  ? 30.62600  20.34900  20.31300  1.000 278.08000 ? 75  PHE A CD2   1 
ATOM   599  C  CE1   . PHE A 1 75  ? 27.87400  20.19400  20.35100  1.000 273.21000 ? 75  PHE A CE1   1 
ATOM   600  C  CE2   . PHE A 1 75  ? 29.94200  20.26500  21.50600  1.000 275.97000 ? 75  PHE A CE2   1 
ATOM   601  C  CZ    . PHE A 1 75  ? 28.57200  20.18600  21.53300  1.000 276.04000 ? 75  PHE A CZ    1 
ATOM   602  N  N     . PRO A 1 76  ? 29.52400  17.24200  16.56100  1.000 278.97000 ? 76  PRO A N     1 
ATOM   603  C  CA    . PRO A 1 76  ? 28.32300  16.58200  16.02000  1.000 281.83000 ? 76  PRO A CA    1 
ATOM   604  C  C     . PRO A 1 76  ? 26.95400  17.12200  16.45600  1.000 284.03000 ? 76  PRO A C     1 
ATOM   605  O  O     . PRO A 1 76  ? 25.99300  16.97300  15.69100  1.000 284.00000 ? 76  PRO A O     1 
ATOM   606  C  CB    . PRO A 1 76  ? 28.53200  15.15200  16.50300  1.000 286.81000 ? 76  PRO A CB    1 
ATOM   607  C  CG    . PRO A 1 76  ? 30.04700  14.97700  16.42900  1.000 283.71000 ? 76  PRO A CG    1 
ATOM   608  C  CD    . PRO A 1 76  ? 30.63300  16.30000  16.79700  1.000 276.11000 ? 76  PRO A CD    1 
ATOM   609  N  N     . GLY A 1 77  ? 26.81900  17.73700  17.63600  1.000 275.85000 ? 77  GLY A N     1 
ATOM   610  C  CA    . GLY A 1 77  ? 25.50600  18.06500  18.17700  1.000 278.98000 ? 77  GLY A CA    1 
ATOM   611  C  C     . GLY A 1 77  ? 25.41200  17.55800  19.60100  1.000 274.77000 ? 77  GLY A C     1 
ATOM   612  O  O     . GLY A 1 77  ? 25.76100  16.39300  19.83300  1.000 276.94000 ? 77  GLY A O     1 
ATOM   613  N  N     . PHE A 1 78  ? 24.99800  18.40100  20.56600  1.000 282.31000 ? 78  PHE A N     1 
ATOM   614  C  CA    . PHE A 1 78  ? 25.09500  17.99600  21.97000  1.000 283.84000 ? 78  PHE A CA    1 
ATOM   615  C  C     . PHE A 1 78  ? 24.60100  16.57200  22.14600  1.000 281.66000 ? 78  PHE A C     1 
ATOM   616  O  O     . PHE A 1 78  ? 25.35500  15.68800  22.58100  1.000 279.48000 ? 78  PHE A O     1 
ATOM   617  C  CB    . PHE A 1 78  ? 24.32900  18.95900  22.87800  1.000 291.07000 ? 78  PHE A CB    1 
ATOM   618  C  CG    . PHE A 1 78  ? 24.69700  18.84800  24.38600  1.000 296.12000 ? 78  PHE A CG    1 
ATOM   619  C  CD1   . PHE A 1 78  ? 24.08800  17.90300  25.21000  1.000 294.17000 ? 78  PHE A CD1   1 
ATOM   620  C  CD2   . PHE A 1 78  ? 25.62100  19.71700  24.98000  1.000 296.09000 ? 78  PHE A CD2   1 
ATOM   621  C  CE1   . PHE A 1 78  ? 24.41600  17.80600  26.57300  1.000 295.00000 ? 78  PHE A CE1   1 
ATOM   622  C  CE2   . PHE A 1 78  ? 25.95700  19.61300  26.34200  1.000 291.80000 ? 78  PHE A CE2   1 
ATOM   623  C  CZ    . PHE A 1 78  ? 25.34900  18.66900  27.13900  1.000 293.23000 ? 78  PHE A CZ    1 
ATOM   624  N  N     . GLU A 1 79  ? 23.38000  16.30100  21.69900  1.000 281.00000 ? 79  GLU A N     1 
ATOM   625  C  CA    . GLU A 1 79  ? 22.83900  14.99100  21.99200  1.000 279.27000 ? 79  GLU A CA    1 
ATOM   626  C  C     . GLU A 1 79  ? 23.66800  13.87900  21.37100  1.000 275.65000 ? 79  GLU A C     1 
ATOM   627  O  O     . GLU A 1 79  ? 23.91500  12.85800  22.02400  1.000 274.02000 ? 79  GLU A O     1 
ATOM   628  C  CB    . GLU A 1 79  ? 21.39500  14.89200  21.54400  1.000 285.94000 ? 79  GLU A CB    1 
ATOM   629  C  CG    . GLU A 1 79  ? 20.79000  13.64600  22.11400  1.000 290.52000 ? 79  GLU A CG    1 
ATOM   630  C  CD    . GLU A 1 79  ? 19.30000  13.71100  22.22900  1.000 299.73000 ? 79  GLU A CD    1 
ATOM   631  O  OE1   . GLU A 1 79  ? 18.73600  12.92100  23.02200  1.000 299.59000 ? 79  GLU A OE1   1 
ATOM   632  O  OE2   . GLU A 1 79  ? 18.69500  14.55600  21.54200  1.000 313.87000 ? 79  GLU A OE2   1 
ATOM   633  N  N     . ALA A 1 80  ? 24.12300  14.05900  20.13200  1.000 272.83000 ? 80  ALA A N     1 
ATOM   634  C  CA    . ALA A 1 80  ? 24.97800  13.04000  19.53500  1.000 273.37000 ? 80  ALA A CA    1 
ATOM   635  C  C     . ALA A 1 80  ? 26.24800  12.82300  20.33500  1.000 280.17000 ? 80  ALA A C     1 
ATOM   636  O  O     . ALA A 1 80  ? 26.70500  11.68200  20.49100  1.000 290.41000 ? 80  ALA A O     1 
ATOM   637  C  CB    . ALA A 1 80  ? 25.33500  13.43900  18.10900  1.000 274.80000 ? 80  ALA A CB    1 
ATOM   638  N  N     . VAL A 1 81  ? 26.83000  13.90800  20.84100  1.000 280.90000 ? 81  VAL A N     1 
ATOM   639  C  CA    . VAL A 1 81  ? 28.16400  13.83100  21.41900  1.000 281.94000 ? 81  VAL A CA    1 
ATOM   640  C  C     . VAL A 1 81  ? 28.11400  13.18700  22.78500  1.000 279.17000 ? 81  VAL A C     1 
ATOM   641  O  O     . VAL A 1 81  ? 28.90000  12.28000  23.09200  1.000 281.19000 ? 81  VAL A O     1 
ATOM   642  C  CB    . VAL A 1 81  ? 28.80400  15.22600  21.50500  1.000 283.17000 ? 81  VAL A CB    1 
ATOM   643  C  CG1   . VAL A 1 81  ? 30.15200  15.12300  22.26600  1.000 280.00000 ? 81  VAL A CG1   1 
ATOM   644  C  CG2   . VAL A 1 81  ? 28.86100  15.89400  20.11500  1.000 281.73000 ? 81  VAL A CG2   1 
ATOM   645  N  N     . PHE A 1 82  ? 27.26100  13.72200  23.64800  1.000 283.82000 ? 82  PHE A N     1 
ATOM   646  C  CA    . PHE A 1 82  ? 27.18700  13.32900  25.03900  1.000 289.98000 ? 82  PHE A CA    1 
ATOM   647  C  C     . PHE A 1 82  ? 26.01100  12.39800  25.31400  1.000 293.63000 ? 82  PHE A C     1 
ATOM   648  O  O     . PHE A 1 82  ? 25.79800  12.01900  26.48100  1.000 299.86000 ? 82  PHE A O     1 
ATOM   649  C  CB    . PHE A 1 82  ? 27.09000  14.58000  25.94900  1.000 289.24000 ? 82  PHE A CB    1 
ATOM   650  C  CG    . PHE A 1 82  ? 28.26500  15.55400  25.81600  1.000 288.03000 ? 82  PHE A CG    1 
ATOM   651  C  CD1   . PHE A 1 82  ? 29.32600  15.49000  26.69500  1.000 287.99000 ? 82  PHE A CD1   1 
ATOM   652  C  CD2   . PHE A 1 82  ? 28.26000  16.58100  24.87900  1.000 291.70000 ? 82  PHE A CD2   1 
ATOM   653  C  CE1   . PHE A 1 82  ? 30.37500  16.39000  26.62800  1.000 288.26000 ? 82  PHE A CE1   1 
ATOM   654  C  CE2   . PHE A 1 82  ? 29.32400  17.48600  24.80600  1.000 293.04000 ? 82  PHE A CE2   1 
ATOM   655  C  CZ    . PHE A 1 82  ? 30.38500  17.38200  25.68000  1.000 289.93000 ? 82  PHE A CZ    1 
ATOM   656  N  N     . GLY A 1 83  ? 25.25000  12.01600  24.28300  1.000 291.48000 ? 83  GLY A N     1 
ATOM   657  C  CA    . GLY A 1 83  ? 24.14000  11.10000  24.46700  1.000 290.34000 ? 83  GLY A CA    1 
ATOM   658  C  C     . GLY A 1 83  ? 23.14300  11.52700  25.52700  1.000 300.12000 ? 83  GLY A C     1 
ATOM   659  O  O     . GLY A 1 83  ? 22.56400  10.66400  26.20300  1.000 300.89000 ? 83  GLY A O     1 
ATOM   660  N  N     . CYS A 1 84  ? 22.95600  12.84300  25.72200  1.000 306.97000 ? 84  CYS A N     1 
ATOM   661  C  CA    . CYS A 1 84  ? 21.93300  13.39500  26.61900  1.000 317.82000 ? 84  CYS A CA    1 
ATOM   662  C  C     . CYS A 1 84  ? 21.51700  14.78600  26.15600  1.000 311.22000 ? 84  CYS A C     1 
ATOM   663  O  O     . CYS A 1 84  ? 22.26100  15.46900  25.45100  1.000 301.78000 ? 84  CYS A O     1 
ATOM   664  C  CB    . CYS A 1 84  ? 22.40500  13.44300  28.07600  1.000 315.56000 ? 84  CYS A CB    1 
ATOM   665  S  SG    . CYS A 1 84  ? 22.61300  15.14600  28.70200  1.000 319.73000 ? 84  CYS A SG    1 
ATOM   666  N  N     . LYS A 1 85  ? 20.32500  15.20700  26.59600  1.000 309.97000 ? 85  LYS A N     1 
ATOM   667  C  CA    . LYS A 1 85  ? 19.72800  16.46500  26.15600  1.000 305.22000 ? 85  LYS A CA    1 
ATOM   668  C  C     . LYS A 1 85  ? 20.04700  17.61600  27.09600  1.000 302.98000 ? 85  LYS A C     1 
ATOM   669  O  O     . LYS A 1 85  ? 19.76700  17.55800  28.29600  1.000 303.78000 ? 85  LYS A O     1 
ATOM   670  C  CB    . LYS A 1 85  ? 18.21100  16.36200  26.00500  1.000 305.96000 ? 85  LYS A CB    1 
ATOM   671  C  CG    . LYS A 1 85  ? 17.61600  15.04100  26.43700  1.000 305.13000 ? 85  LYS A CG    1 
ATOM   672  C  CD    . LYS A 1 85  ? 17.41600  14.97000  27.93300  1.000 303.12000 ? 85  LYS A CD    1 
ATOM   673  C  CE    . LYS A 1 85  ? 16.19200  14.14400  28.24300  1.000 307.63000 ? 85  LYS A CE    1 
ATOM   674  N  NZ    . LYS A 1 85  ? 15.01300  15.03800  28.33700  1.000 312.57000 ? 85  LYS A NZ    1 
ATOM   675  N  N     . TRP A 1 86  ? 20.59900  18.66800  26.53200  1.000 300.28000 ? 86  TRP A N     1 
ATOM   676  C  CA    . TRP A 1 86  ? 20.77300  19.93600  27.20500  1.000 300.93000 ? 86  TRP A CA    1 
ATOM   677  C  C     . TRP A 1 86  ? 19.75600  20.87200  26.56700  1.000 302.96000 ? 86  TRP A C     1 
ATOM   678  O  O     . TRP A 1 86  ? 20.09000  21.65300  25.67600  1.000 299.04000 ? 86  TRP A O     1 
ATOM   679  C  CB    . TRP A 1 86  ? 22.20500  20.38700  27.03600  1.000 298.44000 ? 86  TRP A CB    1 
ATOM   680  C  CG    . TRP A 1 86  ? 22.47300  21.65300  27.66400  1.000 296.90000 ? 86  TRP A CG    1 
ATOM   681  C  CD1   . TRP A 1 86  ? 21.68600  22.28700  28.55700  1.000 300.01000 ? 86  TRP A CD1   1 
ATOM   682  C  CD2   . TRP A 1 86  ? 23.62600  22.49000  27.46100  1.000 291.20000 ? 86  TRP A CD2   1 
ATOM   683  N  NE1   . TRP A 1 86  ? 22.26900  23.46600  28.93000  1.000 298.94000 ? 86  TRP A NE1   1 
ATOM   684  C  CE2   . TRP A 1 86  ? 23.46700  23.60600  28.27600  1.000 293.46000 ? 86  TRP A CE2   1 
ATOM   685  C  CE3   . TRP A 1 86  ? 24.77500  22.39400  26.67000  1.000 285.02000 ? 86  TRP A CE3   1 
ATOM   686  C  CZ2   . TRP A 1 86  ? 24.39400  24.63300  28.30700  1.000 291.01000 ? 86  TRP A CZ2   1 
ATOM   687  C  CZ3   . TRP A 1 86  ? 25.72000  23.40500  26.72500  1.000 284.06000 ? 86  TRP A CZ3   1 
ATOM   688  C  CH2   . TRP A 1 86  ? 25.51900  24.51500  27.53400  1.000 285.51000 ? 86  TRP A CH2   1 
ATOM   689  N  N     . GLU A 1 87  ? 18.51500  20.79000  27.04400  1.000 304.99000 ? 87  GLU A N     1 
ATOM   690  C  CA    . GLU A 1 87  ? 17.36300  21.34800  26.33800  1.000 308.21000 ? 87  GLU A CA    1 
ATOM   691  C  C     . GLU A 1 87  ? 17.17900  22.84000  26.58300  1.000 305.96000 ? 87  GLU A C     1 
ATOM   692  O  O     . GLU A 1 87  ? 17.34900  23.32100  27.70600  1.000 307.03000 ? 87  GLU A O     1 
ATOM   693  C  CB    . GLU A 1 87  ? 16.08000  20.63000  26.75800  1.000 315.98000 ? 87  GLU A CB    1 
ATOM   694  C  CG    . GLU A 1 87  ? 15.86400  19.28100  26.08800  1.000 309.72000 ? 87  GLU A CG    1 
ATOM   695  C  CD    . GLU A 1 87  ? 14.56800  18.61900  26.51400  1.000 316.44000 ? 87  GLU A CD    1 
ATOM   696  O  OE1   . GLU A 1 87  ? 14.23600  18.65600  27.72100  1.000 323.38000 ? 87  GLU A OE1   1 
ATOM   697  O  OE2   . GLU A 1 87  ? 13.87300  18.06600  25.63500  1.000 322.00000 ? 87  GLU A OE2   1 
ATOM   698  N  N     . SER A 1 88  ? 16.78100  23.55900  25.52500  1.000 305.45000 ? 88  SER A N     1 
ATOM   699  C  CA    . SER A 1 88  ? 16.40000  24.95800  25.65900  1.000 306.08000 ? 88  SER A CA    1 
ATOM   700  C  C     . SER A 1 88  ? 14.95700  25.12000  26.09400  1.000 310.68000 ? 88  SER A C     1 
ATOM   701  O  O     . SER A 1 88  ? 14.59800  26.17200  26.63700  1.000 312.04000 ? 88  SER A O     1 
ATOM   702  C  CB    . SER A 1 88  ? 16.63400  25.68800  24.34600  1.000 304.97000 ? 88  SER A CB    1 
ATOM   703  O  OG    . SER A 1 88  ? 16.48700  24.80800  23.23800  1.000 314.45000 ? 88  SER A OG    1 
ATOM   704  N  N     . GLN A 1 89  ? 14.11300  24.11900  25.83400  1.000 313.09000 ? 89  GLN A N     1 
ATOM   705  C  CA    . GLN A 1 89  ? 12.76500  24.14200  26.39000  1.000 318.75000 ? 89  GLN A CA    1 
ATOM   706  C  C     . GLN A 1 89  ? 12.82000  24.19300  27.91100  1.000 319.56000 ? 89  GLN A C     1 
ATOM   707  O  O     . GLN A 1 89  ? 11.99800  24.85500  28.55800  1.000 311.71000 ? 89  GLN A O     1 
ATOM   708  C  CB    . GLN A 1 89  ? 11.98200  22.91200  25.92000  1.000 317.10000 ? 89  GLN A CB    1 
ATOM   709  C  CG    . GLN A 1 89  ? 12.26500  21.60900  26.70500  1.000 324.69000 ? 89  GLN A CG    1 
ATOM   710  C  CD    . GLN A 1 89  ? 11.06600  20.69600  26.73200  1.000 322.23000 ? 89  GLN A CD    1 
ATOM   711  O  OE1   . GLN A 1 89  ? 10.06400  20.99000  26.09200  1.000 324.15000 ? 89  GLN A OE1   1 
ATOM   712  N  NE2   . GLN A 1 89  ? 11.15200  19.59100  27.47700  1.000 315.51000 ? 89  GLN A NE2   1 
ATOM   713  N  N     . ASN A 1 90  ? 13.81200  23.52400  28.49400  1.000 314.72000 ? 90  ASN A N     1 
ATOM   714  C  CA    . ASN A 1 90  ? 13.86600  23.29100  29.92600  1.000 307.48000 ? 90  ASN A CA    1 
ATOM   715  C  C     . ASN A 1 90  ? 14.85800  24.26900  30.52900  1.000 307.02000 ? 90  ASN A C     1 
ATOM   716  O  O     . ASN A 1 90  ? 16.01800  23.94400  30.76500  1.000 308.85000 ? 90  ASN A O     1 
ATOM   717  C  CB    . ASN A 1 90  ? 14.28200  21.86600  30.21500  1.000 307.79000 ? 90  ASN A CB    1 
ATOM   718  C  CG    . ASN A 1 90  ? 14.49300  21.64000  31.67100  1.000 313.17000 ? 90  ASN A CG    1 
ATOM   719  O  OD1   . ASN A 1 90  ? 13.56800  21.26800  32.38200  1.000 330.10000 ? 90  ASN A OD1   1 
ATOM   720  N  ND2   . ASN A 1 90  ? 15.68500  21.95600  32.14600  1.000 309.41000 ? 90  ASN A ND2   1 
ATOM   721  N  N     . ILE A 1 91  ? 14.39100  25.48000  30.77800  1.000 300.57000 ? 91  ILE A N     1 
ATOM   722  C  CA    . ILE A 1 91  ? 15.24300  26.53900  31.29800  1.000 303.85000 ? 91  ILE A CA    1 
ATOM   723  C  C     . ILE A 1 91  ? 14.63100  27.06000  32.58300  1.000 305.71000 ? 91  ILE A C     1 
ATOM   724  O  O     . ILE A 1 91  ? 13.40900  27.16100  32.72500  1.000 309.68000 ? 91  ILE A O     1 
ATOM   725  C  CB    . ILE A 1 91  ? 15.45400  27.66600  30.25200  1.000 313.66000 ? 91  ILE A CB    1 
ATOM   726  C  CG1   . ILE A 1 91  ? 16.36500  27.09100  29.15600  1.000 315.86000 ? 91  ILE A CG1   1 
ATOM   727  C  CG2   . ILE A 1 91  ? 15.94900  29.01900  30.92200  1.000 316.72000 ? 91  ILE A CG2   1 
ATOM   728  C  CD1   . ILE A 1 91  ? 16.75800  27.98000  28.04900  1.000 307.48000 ? 91  ILE A CD1   1 
ATOM   729  N  N     . VAL A 1 92  ? 15.49100  27.36500  33.53100  1.000 302.96000 ? 92  VAL A N     1 
ATOM   730  C  CA    . VAL A 1 92  ? 15.07900  27.86800  34.81300  1.000 294.97000 ? 92  VAL A CA    1 
ATOM   731  C  C     . VAL A 1 92  ? 15.73000  29.23800  34.94500  1.000 294.96000 ? 92  VAL A C     1 
ATOM   732  O  O     . VAL A 1 92  ? 16.89400  29.38600  35.35500  1.000 293.15000 ? 92  VAL A O     1 
ATOM   733  C  CB    . VAL A 1 92  ? 15.47900  26.90300  35.92700  1.000 302.37000 ? 92  VAL A CB    1 
ATOM   734  C  CG1   . VAL A 1 92  ? 15.09700  27.37800  37.27100  1.000 319.23000 ? 92  VAL A CG1   1 
ATOM   735  C  CG2   . VAL A 1 92  ? 14.83700  25.51300  35.67900  1.000 309.12000 ? 92  VAL A CG2   1 
ATOM   736  N  N     . PHE A 1 93  ? 14.95800  30.25600  34.64300  1.000 299.18000 ? 93  PHE A N     1 
ATOM   737  C  CA    . PHE A 1 93  ? 15.48700  31.60100  34.48600  1.000 295.85000 ? 93  PHE A CA    1 
ATOM   738  C  C     . PHE A 1 93  ? 15.32700  32.43400  35.76600  1.000 306.45000 ? 93  PHE A C     1 
ATOM   739  O  O     . PHE A 1 93  ? 14.20100  32.55700  36.25000  1.000 320.10000 ? 93  PHE A O     1 
ATOM   740  C  CB    . PHE A 1 93  ? 14.71000  32.25900  33.33400  1.000 297.45000 ? 93  PHE A CB    1 
ATOM   741  C  CG    . PHE A 1 93  ? 15.02400  33.67100  33.14600  1.000 300.37000 ? 93  PHE A CG    1 
ATOM   742  C  CD1   . PHE A 1 93  ? 14.08300  34.58900  32.74300  1.000 297.77000 ? 93  PHE A CD1   1 
ATOM   743  C  CD2   . PHE A 1 93  ? 16.33700  34.03200  33.24700  1.000 301.73000 ? 93  PHE A CD2   1 
ATOM   744  C  CE1   . PHE A 1 93  ? 14.44400  35.92800  32.52500  1.000 298.33000 ? 93  PHE A CE1   1 
ATOM   745  C  CE2   . PHE A 1 93  ? 16.78500  35.40800  32.98600  1.000 301.70000 ? 93  PHE A CE2   1 
ATOM   746  C  CZ    . PHE A 1 93  ? 15.75800  36.30500  32.64500  1.000 296.52000 ? 93  PHE A CZ    1 
ATOM   747  N  N     . LYS A 1 94  ? 16.38900  33.15100  36.20600  1.000 304.42000 ? 94  LYS A N     1 
ATOM   748  C  CA    . LYS A 1 94  ? 16.28600  34.24400  37.17800  1.000 307.36000 ? 94  LYS A CA    1 
ATOM   749  C  C     . LYS A 1 94  ? 16.66600  35.49900  36.42100  1.000 308.33000 ? 94  LYS A C     1 
ATOM   750  O  O     . LYS A 1 94  ? 17.83200  35.68100  36.04600  1.000 305.35000 ? 94  LYS A O     1 
ATOM   751  C  CB    . LYS A 1 94  ? 17.17100  34.02700  38.40800  1.000 307.12000 ? 94  LYS A CB    1 
ATOM   752  C  CG    . LYS A 1 94  ? 16.35000  34.02500  39.74600  1.000 314.04000 ? 94  LYS A CG    1 
ATOM   753  C  CD    . LYS A 1 94  ? 15.59300  35.35100  40.08500  1.000 321.42000 ? 94  LYS A CD    1 
ATOM   754  C  CE    . LYS A 1 94  ? 15.04500  35.34300  41.52000  1.000 314.10000 ? 94  LYS A CE    1 
ATOM   755  N  NZ    . LYS A 1 94  ? 14.10500  36.47400  41.76600  1.000 299.52000 ? 94  LYS A NZ    1 
ATOM   756  N  N     . GLU A 1 95  ? 15.67800  36.35500  36.22000  1.000 314.61000 ? 95  GLU A N     1 
ATOM   757  C  CA    . GLU A 1 95  ? 15.88000  37.51100  35.39100  1.000 307.61000 ? 95  GLU A CA    1 
ATOM   758  C  C     . GLU A 1 95  ? 16.76400  38.54700  36.05600  1.000 310.71000 ? 95  GLU A C     1 
ATOM   759  O  O     . GLU A 1 95  ? 16.84900  38.66100  37.27500  1.000 315.40000 ? 95  GLU A O     1 
ATOM   760  C  CB    . GLU A 1 95  ? 14.56100  38.16500  35.03300  1.000 299.05000 ? 95  GLU A CB    1 
ATOM   761  C  CG    . GLU A 1 95  ? 14.76600  39.25700  34.00900  1.000 298.69000 ? 95  GLU A CG    1 
ATOM   762  C  CD    . GLU A 1 95  ? 13.61700  40.16700  33.94600  1.000 306.68000 ? 95  GLU A CD    1 
ATOM   763  O  OE1   . GLU A 1 95  ? 13.26100  40.56400  32.82700  1.000 306.82000 ? 95  GLU A OE1   1 
ATOM   764  O  OE2   . GLU A 1 95  ? 13.05200  40.47900  35.00900  1.000 311.27000 ? 95  GLU A OE2   1 
ATOM   765  N  N     . ILE A 1 96  ? 17.41500  39.32800  35.22100  1.000 314.72000 ? 96  ILE A N     1 
ATOM   766  C  CA    . ILE A 1 96  ? 17.97300  40.61300  35.61000  1.000 319.03000 ? 96  ILE A CA    1 
ATOM   767  C  C     . ILE A 1 96  ? 17.51400  41.62000  34.55600  1.000 317.85000 ? 96  ILE A C     1 
ATOM   768  O  O     . ILE A 1 96  ? 17.32900  41.27000  33.38500  1.000 318.34000 ? 96  ILE A O     1 
ATOM   769  C  CB    . ILE A 1 96  ? 19.52700  40.54200  35.77500  1.000 324.20000 ? 96  ILE A CB    1 
ATOM   770  C  CG1   . ILE A 1 96  ? 19.89200  39.88500  37.12900  1.000 311.80000 ? 96  ILE A CG1   1 
ATOM   771  C  CG2   . ILE A 1 96  ? 20.15000  41.91400  35.66100  1.000 331.47000 ? 96  ILE A CG2   1 
ATOM   772  C  CD1   . ILE A 1 96  ? 21.33200  39.46200  37.32000  1.000 309.67000 ? 96  ILE A CD1   1 
ATOM   773  N  N     . THR A 1 97  ? 17.25500  42.86000  34.99000  1.000 320.27000 ? 97  THR A N     1 
ATOM   774  C  CA    . THR A 1 97  ? 16.79400  43.90600  34.09000  1.000 318.45000 ? 97  THR A CA    1 
ATOM   775  C  C     . THR A 1 97  ? 17.80500  45.03500  34.01500  1.000 328.60000 ? 97  THR A C     1 
ATOM   776  O  O     . THR A 1 97  ? 18.60200  45.24800  34.93800  1.000 333.40000 ? 97  THR A O     1 
ATOM   777  C  CB    . THR A 1 97  ? 15.42900  44.46300  34.49700  1.000 321.17000 ? 97  THR A CB    1 
ATOM   778  O  OG1   . THR A 1 97  ? 15.28000  44.43500  35.92000  1.000 320.46000 ? 97  THR A OG1   1 
ATOM   779  C  CG2   . THR A 1 97  ? 14.29900  43.69600  33.83400  1.000 318.65000 ? 97  THR A CG2   1 
ATOM   780  N  N     . ASP A 1 98  ? 17.75700  45.73400  32.86900  1.000 335.36000 ? 98  ASP A N     1 
ATOM   781  C  CA    . ASP A 1 98  ? 18.59500  46.90900  32.65300  1.000 335.02000 ? 98  ASP A CA    1 
ATOM   782  C  C     . ASP A 1 98  ? 18.45800  47.88600  33.81100  1.000 331.98000 ? 98  ASP A C     1 
ATOM   783  O  O     . ASP A 1 98  ? 19.45300  48.47700  34.26000  1.000 333.74000 ? 98  ASP A O     1 
ATOM   784  C  CB    . ASP A 1 98  ? 18.21000  47.56000  31.30800  1.000 332.67000 ? 98  ASP A CB    1 
ATOM   785  C  CG    . ASP A 1 98  ? 18.06700  46.51500  30.15800  1.000 324.79000 ? 98  ASP A CG    1 
ATOM   786  O  OD1   . ASP A 1 98  ? 18.95300  46.42500  29.28200  1.000 322.98000 ? 98  ASP A OD1   1 
ATOM   787  O  OD2   . ASP A 1 98  ? 17.07000  45.77700  30.14300  1.000 321.76000 ? 98  ASP A OD2   1 
ATOM   788  N  N     . GLU A 1 99  ? 17.23200  48.03400  34.32700  1.000 335.64000 ? 99  GLU A N     1 
ATOM   789  C  CA    . GLU A 1 99  ? 17.02900  48.84200  35.52200  1.000 336.28000 ? 99  GLU A CA    1 
ATOM   790  C  C     . GLU A 1 99  ? 17.93700  48.37700  36.64300  1.000 338.42000 ? 99  GLU A C     1 
ATOM   791  O  O     . GLU A 1 99  ? 18.57900  49.19500  37.31500  1.000 342.51000 ? 99  GLU A O     1 
ATOM   792  C  CB    . GLU A 1 99  ? 15.57600  48.77600  35.97100  1.000 333.62000 ? 99  GLU A CB    1 
ATOM   793  C  CG    . GLU A 1 99  ? 14.62000  49.50300  35.06000  1.000 348.23000 ? 99  GLU A CG    1 
ATOM   794  C  CD    . GLU A 1 99  ? 14.07100  48.61300  33.96300  1.000 345.23000 ? 99  GLU A CD    1 
ATOM   795  O  OE1   . GLU A 1 99  ? 14.22300  48.96100  32.77200  1.000 346.43000 ? 99  GLU A OE1   1 
ATOM   796  O  OE2   . GLU A 1 99  ? 13.49300  47.55800  34.29300  1.000 348.58000 ? 99  GLU A OE2   1 
ATOM   797  N  N     . GLU A 1 100 ? 18.02100  47.05700  36.84600  1.000 339.35000 ? 100 GLU A N     1 
ATOM   798  C  CA    . GLU A 1 100 ? 19.00000  46.53800  37.79300  1.000 343.38000 ? 100 GLU A CA    1 
ATOM   799  C  C     . GLU A 1 100 ? 20.41600  46.75500  37.28500  1.000 351.04000 ? 100 GLU A C     1 
ATOM   800  O  O     . GLU A 1 100 ? 21.29300  47.15800  38.05900  1.000 352.46000 ? 100 GLU A O     1 
ATOM   801  C  CB    . GLU A 1 100 ? 18.74800  45.06000  38.06400  1.000 338.02000 ? 100 GLU A CB    1 
ATOM   802  C  CG    . GLU A 1 100 ? 17.28600  44.69700  38.22200  1.000 331.15000 ? 100 GLU A CG    1 
ATOM   803  C  CD    . GLU A 1 100 ? 17.05700  43.61000  39.24900  1.000 326.69000 ? 100 GLU A CD    1 
ATOM   804  O  OE1   . GLU A 1 100 ? 18.04500  43.09100  39.81600  1.000 322.10000 ? 100 GLU A OE1   1 
ATOM   805  O  OE2   . GLU A 1 100 ? 15.87600  43.28400  39.50900  1.000 327.88000 ? 100 GLU A OE2   1 
ATOM   806  N  N     . ILE A 1 101 ? 20.65700  46.50700  35.98900  1.000 353.42000 ? 101 ILE A N     1 
ATOM   807  C  CA    . ILE A 1 101 ? 21.99200  46.72300  35.43500  1.000 345.84000 ? 101 ILE A CA    1 
ATOM   808  C  C     . ILE A 1 101 ? 22.38300  48.19400  35.57300  1.000 343.81000 ? 101 ILE A C     1 
ATOM   809  O  O     . ILE A 1 101 ? 23.38500  48.52700  36.21700  1.000 348.44000 ? 101 ILE A O     1 
ATOM   810  C  CB    . ILE A 1 101 ? 22.08000  46.23500  33.97200  1.000 345.38000 ? 101 ILE A CB    1 
ATOM   811  C  CG1   . ILE A 1 101 ? 21.84000  44.72900  33.86900  1.000 348.76000 ? 101 ILE A CG1   1 
ATOM   812  C  CG2   . ILE A 1 101 ? 23.46300  46.52700  33.39000  1.000 339.86000 ? 101 ILE A CG2   1 
ATOM   813  C  CD1   . ILE A 1 101 ? 21.99900  44.13600  32.45100  1.000 339.78000 ? 101 ILE A CD1   1 
ATOM   814  N  N     . ARG A 1 102 ? 21.55100  49.09900  35.05200  1.000 332.42000 ? 102 ARG A N     1 
ATOM   815  C  CA    . ARG A 1 102 ? 21.87300  50.52300  35.11200  1.000 331.27000 ? 102 ARG A CA    1 
ATOM   816  C  C     . ARG A 1 102 ? 22.07400  51.00300  36.54500  1.000 334.89000 ? 102 ARG A C     1 
ATOM   817  O  O     . ARG A 1 102 ? 23.07000  51.66400  36.84100  1.000 337.90000 ? 102 ARG A O     1 
ATOM   818  C  CB    . ARG A 1 102 ? 20.77300  51.33000  34.43600  1.000 325.66000 ? 102 ARG A CB    1 
ATOM   819  C  CG    . ARG A 1 102 ? 20.60400  50.97700  33.00100  1.000 326.26000 ? 102 ARG A CG    1 
ATOM   820  C  CD    . ARG A 1 102 ? 19.18900  51.20300  32.57000  1.000 322.48000 ? 102 ARG A CD    1 
ATOM   821  N  NE    . ARG A 1 102 ? 18.98400  50.69200  31.22400  1.000 320.90000 ? 102 ARG A NE    1 
ATOM   822  C  CZ    . ARG A 1 102 ? 18.09300  51.18500  30.37500  1.000 318.83000 ? 102 ARG A CZ    1 
ATOM   823  N  NH1   . ARG A 1 102 ? 17.33600  52.21200  30.74600  1.000 315.39000 ? 102 ARG A NH1   1 
ATOM   824  N  NH2   . ARG A 1 102 ? 17.96600  50.66700  29.15900  1.000 323.56000 ? 102 ARG A NH2   1 
ATOM   825  N  N     . ARG A 1 103 ? 21.15500  50.64800  37.45000  1.000 345.31000 ? 103 ARG A N     1 
ATOM   826  C  CA    . ARG A 1 103 ? 21.20400  51.12300  38.83500  1.000 343.09000 ? 103 ARG A CA    1 
ATOM   827  C  C     . ARG A 1 103 ? 22.51800  50.74900  39.52400  1.000 348.08000 ? 103 ARG A C     1 
ATOM   828  O  O     . ARG A 1 103 ? 23.15900  51.59700  40.16500  1.000 340.48000 ? 103 ARG A O     1 
ATOM   829  C  CB    . ARG A 1 103 ? 20.02000  50.56900  39.60700  1.000 336.76000 ? 103 ARG A CB    1 
ATOM   830  C  CG    . ARG A 1 103 ? 20.05600  50.78000  41.09200  1.000 332.36000 ? 103 ARG A CG    1 
ATOM   831  C  CD    . ARG A 1 103 ? 18.64500  50.74400  41.63200  1.000 331.05000 ? 103 ARG A CD    1 
ATOM   832  N  NE    . ARG A 1 103 ? 17.96900  49.46300  41.40100  1.000 331.63000 ? 103 ARG A NE    1 
ATOM   833  C  CZ    . ARG A 1 103 ? 16.95100  49.27700  40.56000  1.000 330.89000 ? 103 ARG A CZ    1 
ATOM   834  N  NH1   . ARG A 1 103 ? 16.48500  50.29200  39.84600  1.000 329.25000 ? 103 ARG A NH1   1 
ATOM   835  N  NH2   . ARG A 1 103 ? 16.39600  48.07300  40.43300  1.000 327.01000 ? 103 ARG A NH2   1 
ATOM   836  N  N     . TYR A 1 104 ? 22.94500  49.47900  39.40800  1.000 356.70000 ? 104 TYR A N     1 
ATOM   837  C  CA    . TYR A 1 104 ? 24.17200  49.05200  40.10200  1.000 353.47000 ? 104 TYR A CA    1 
ATOM   838  C  C     . TYR A 1 104 ? 25.43900  49.32100  39.29100  1.000 357.40000 ? 104 TYR A C     1 
ATOM   839  O  O     . TYR A 1 104 ? 26.50000  49.58500  39.87700  1.000 354.68000 ? 104 TYR A O     1 
ATOM   840  C  CB    . TYR A 1 104 ? 24.11300  47.56000  40.46900  1.000 345.85000 ? 104 TYR A CB    1 
ATOM   841  C  CG    . TYR A 1 104 ? 22.94500  47.16100  41.31700  1.000 338.29000 ? 104 TYR A CG    1 
ATOM   842  C  CD1   . TYR A 1 104 ? 22.83600  47.58100  42.63100  1.000 335.93000 ? 104 TYR A CD1   1 
ATOM   843  C  CD2   . TYR A 1 104 ? 21.95500  46.33800  40.80000  1.000 332.63000 ? 104 TYR A CD2   1 
ATOM   844  C  CE1   . TYR A 1 104 ? 21.76700  47.20700  43.39800  1.000 334.95000 ? 104 TYR A CE1   1 
ATOM   845  C  CE2   . TYR A 1 104 ? 20.88000  45.96600  41.55800  1.000 333.17000 ? 104 TYR A CE2   1 
ATOM   846  C  CZ    . TYR A 1 104 ? 20.78900  46.39500  42.85400  1.000 332.90000 ? 104 TYR A CZ    1 
ATOM   847  O  OH    . TYR A 1 104 ? 19.71600  46.01500  43.61900  1.000 348.03000 ? 104 TYR A OH    1 
ATOM   848  N  N     . LEU A 1 105 ? 25.35100  49.27200  37.95500  1.000 363.62000 ? 105 LEU A N     1 
ATOM   849  C  CA    . LEU A 1 105 ? 26.55000  49.37900  37.12100  1.000 359.57000 ? 105 LEU A CA    1 
ATOM   850  C  C     . LEU A 1 105 ? 27.15500  50.79000  37.13300  1.000 362.38000 ? 105 LEU A C     1 
ATOM   851  O  O     . LEU A 1 105 ? 28.37900  50.93500  37.08400  1.000 363.86000 ? 105 LEU A O     1 
ATOM   852  C  CB    . LEU A 1 105 ? 26.24500  48.94000  35.67300  1.000 349.04000 ? 105 LEU A CB    1 
ATOM   853  C  CG    . LEU A 1 105 ? 27.20300  49.24700  34.53100  1.000 347.34000 ? 105 LEU A CG    1 
ATOM   854  C  CD1   . LEU A 1 105 ? 28.54900  48.51100  34.67900  1.000 341.59000 ? 105 LEU A CD1   1 
ATOM   855  C  CD2   . LEU A 1 105 ? 26.56900  48.97300  33.15500  1.000 348.28000 ? 105 LEU A CD2   1 
ATOM   856  N  N     . PHE A 1 106 ? 26.33500  51.84600  37.20500  1.000 354.13000 ? 106 PHE A N     1 
ATOM   857  C  CA    . PHE A 1 106 ? 26.85700  53.16900  36.84200  1.000 348.75000 ? 106 PHE A CA    1 
ATOM   858  C  C     . PHE A 1 106 ? 27.74300  53.82200  37.90400  1.000 349.34000 ? 106 PHE A C     1 
ATOM   859  O  O     . PHE A 1 106 ? 28.29000  54.90000  37.62600  1.000 357.27000 ? 106 PHE A O     1 
ATOM   860  C  CB    . PHE A 1 106 ? 25.70700  54.13100  36.48100  1.000 351.81000 ? 106 PHE A CB    1 
ATOM   861  C  CG    . PHE A 1 106 ? 25.18800  53.93500  35.07900  1.000 355.82000 ? 106 PHE A CG    1 
ATOM   862  C  CD1   . PHE A 1 106 ? 26.01700  54.05400  33.97200  1.000 359.73000 ? 106 PHE A CD1   1 
ATOM   863  C  CD2   . PHE A 1 106 ? 23.85300  53.64100  34.87800  1.000 351.35000 ? 106 PHE A CD2   1 
ATOM   864  C  CE1   . PHE A 1 106 ? 25.51300  53.86400  32.68800  1.000 357.14000 ? 106 PHE A CE1   1 
ATOM   865  C  CE2   . PHE A 1 106 ? 23.35500  53.44700  33.61300  1.000 340.18000 ? 106 PHE A CE2   1 
ATOM   866  C  CZ    . PHE A 1 106 ? 24.17600  53.56000  32.51700  1.000 347.38000 ? 106 PHE A CZ    1 
ATOM   867  N  N     . ASN A 1 107 ? 27.89900  53.22000  39.08600  1.000 359.43000 ? 107 ASN A N     1 
ATOM   868  C  CA    . ASN A 1 107 ? 28.71200  53.78900  40.16200  1.000 363.45000 ? 107 ASN A CA    1 
ATOM   869  C  C     . ASN A 1 107 ? 30.09800  54.24700  39.68200  1.000 364.76000 ? 107 ASN A C     1 
ATOM   870  O  O     . ASN A 1 107 ? 30.70700  53.62800  38.79600  1.000 365.25000 ? 107 ASN A O     1 
ATOM   871  C  CB    . ASN A 1 107 ? 28.84200  52.73400  41.27300  1.000 360.21000 ? 107 ASN A CB    1 
ATOM   872  C  CG    . ASN A 1 107 ? 29.68600  53.19800  42.45700  1.000 359.32000 ? 107 ASN A CG    1 
ATOM   873  O  OD1   . ASN A 1 107 ? 30.91600  53.19100  42.40500  1.000 362.00000 ? 107 ASN A OD1   1 
ATOM   874  N  ND2   . ASN A 1 107 ? 29.01700  53.53200  43.56300  1.000 353.74000 ? 107 ASN A ND2   1 
ATOM   875  N  N     . ALA A 1 108 ? 30.59200  55.35300  40.27500  1.000 363.51000 ? 108 ALA A N     1 
ATOM   876  C  CA    . ALA A 1 108 ? 31.89400  55.89800  39.88100  1.000 358.99000 ? 108 ALA A CA    1 
ATOM   877  C  C     . ALA A 1 108 ? 33.01800  54.89700  40.10800  1.000 351.57000 ? 108 ALA A C     1 
ATOM   878  O  O     . ALA A 1 108 ? 33.87200  54.70800  39.23900  1.000 347.84000 ? 108 ALA A O     1 
ATOM   879  C  CB    . ALA A 1 108 ? 32.17900  57.19400  40.64200  1.000 370.01000 ? 108 ALA A CB    1 
ATOM   880  N  N     . SER A 1 109 ? 33.06000  54.27100  41.28000  1.000 351.36000 ? 109 SER A N     1 
ATOM   881  C  CA    . SER A 1 109 ? 34.04700  53.22700  41.50700  1.000 349.38000 ? 109 SER A CA    1 
ATOM   882  C  C     . SER A 1 109 ? 33.76100  52.03300  40.61500  1.000 346.16000 ? 109 SER A C     1 
ATOM   883  O  O     . SER A 1 109 ? 32.61100  51.62800  40.43800  1.000 351.11000 ? 109 SER A O     1 
ATOM   884  C  CB    . SER A 1 109 ? 34.04400  52.76300  42.96200  1.000 346.63000 ? 109 SER A CB    1 
ATOM   885  O  OG    . SER A 1 109 ? 34.34200  51.37200  43.02900  1.000 336.59000 ? 109 SER A OG    1 
ATOM   886  N  N     . THR A 1 110 ? 34.82200  51.45600  40.06200  1.000 348.52000 ? 110 THR A N     1 
ATOM   887  C  CA    . THR A 1 110 ? 34.68200  50.13900  39.46300  1.000 348.35000 ? 110 THR A CA    1 
ATOM   888  C  C     . THR A 1 110 ? 34.31200  49.10700  40.52700  1.000 342.88000 ? 110 THR A C     1 
ATOM   889  O  O     . THR A 1 110 ? 33.37500  48.32700  40.34100  1.000 343.16000 ? 110 THR A O     1 
ATOM   890  C  CB    . THR A 1 110 ? 35.96900  49.75300  38.71500  1.000 352.27000 ? 110 THR A CB    1 
ATOM   891  O  OG1   . THR A 1 110 ? 36.00100  50.40400  37.43600  1.000 352.89000 ? 110 THR A OG1   1 
ATOM   892  C  CG2   . THR A 1 110 ? 36.07200  48.24800  38.51100  1.000 351.69000 ? 110 THR A CG2   1 
ATOM   893  N  N     . HIS A 1 111 ? 34.99700  49.12300  41.67800  1.000 335.78000 ? 111 HIS A N     1 
ATOM   894  C  CA    . HIS A 1 111 ? 34.83700  48.04100  42.65100  1.000 329.16000 ? 111 HIS A CA    1 
ATOM   895  C  C     . HIS A 1 111 ? 33.44600  48.04400  43.26300  1.000 331.86000 ? 111 HIS A C     1 
ATOM   896  O  O     . HIS A 1 111 ? 32.79600  46.99700  43.35100  1.000 332.80000 ? 111 HIS A O     1 
ATOM   897  C  CB    . HIS A 1 111 ? 35.89900  48.13500  43.74600  1.000 324.10000 ? 111 HIS A CB    1 
ATOM   898  C  CG    . HIS A 1 111 ? 37.29300  47.93000  43.24400  1.000 332.56000 ? 111 HIS A CG    1 
ATOM   899  N  ND1   . HIS A 1 111 ? 37.66300  48.21500  41.94800  1.000 342.27000 ? 111 HIS A ND1   1 
ATOM   900  C  CD2   . HIS A 1 111 ? 38.40200  47.45300  43.85500  1.000 338.27000 ? 111 HIS A CD2   1 
ATOM   901  C  CE1   . HIS A 1 111 ? 38.94500  47.94300  41.78700  1.000 348.37000 ? 111 HIS A CE1   1 
ATOM   902  N  NE2   . HIS A 1 111 ? 39.41500  47.46900  42.92600  1.000 346.34000 ? 111 HIS A NE2   1 
ATOM   903  N  N     . LYS A 1 112 ? 32.97800  49.20800  43.71300  1.000 334.80000 ? 112 LYS A N     1 
ATOM   904  C  CA    . LYS A 1 112 ? 31.60900  49.28200  44.21000  1.000 337.58000 ? 112 LYS A CA    1 
ATOM   905  C  C     . LYS A 1 112 ? 30.60500  48.98700  43.10300  1.000 336.06000 ? 112 LYS A C     1 
ATOM   906  O  O     . LYS A 1 112 ? 29.53200  48.42700  43.36400  1.000 331.36000 ? 112 LYS A O     1 
ATOM   907  C  CB    . LYS A 1 112 ? 31.33500  50.64800  44.83400  1.000 345.26000 ? 112 LYS A CB    1 
ATOM   908  C  CG    . LYS A 1 112 ? 30.13300  50.62400  45.74600  1.000 344.14000 ? 112 LYS A CG    1 
ATOM   909  C  CD    . LYS A 1 112 ? 29.81900  51.98900  46.27200  1.000 341.62000 ? 112 LYS A CD    1 
ATOM   910  C  CE    . LYS A 1 112 ? 28.44400  51.96800  46.87000  1.000 330.67000 ? 112 LYS A CE    1 
ATOM   911  N  NZ    . LYS A 1 112 ? 27.76800  53.26400  46.67700  1.000 333.65000 ? 112 LYS A NZ    1 
ATOM   912  N  N     . ARG A 1 113 ? 30.92700  49.36200  41.86300  1.000 343.26000 ? 113 ARG A N     1 
ATOM   913  C  CA    . ARG A 1 113 ? 30.14500  48.87500  40.73400  1.000 343.45000 ? 113 ARG A CA    1 
ATOM   914  C  C     . ARG A 1 113 ? 30.28400  47.36400  40.60700  1.000 337.51000 ? 113 ARG A C     1 
ATOM   915  O  O     . ARG A 1 113 ? 29.28000  46.64800  40.51100  1.000 334.78000 ? 113 ARG A O     1 
ATOM   916  C  CB    . ARG A 1 113 ? 30.57400  49.59800  39.44800  1.000 353.40000 ? 113 ARG A CB    1 
ATOM   917  C  CG    . ARG A 1 113 ? 30.77300  48.73200  38.19200  1.000 347.86000 ? 113 ARG A CG    1 
ATOM   918  C  CD    . ARG A 1 113 ? 31.07100  49.57400  36.94700  1.000 347.57000 ? 113 ARG A CD    1 
ATOM   919  N  NE    . ARG A 1 113 ? 32.36300  50.23500  36.97700  1.000 353.10000 ? 113 ARG A NE    1 
ATOM   920  C  CZ    . ARG A 1 113 ? 32.58000  51.45300  36.49100  1.000 357.38000 ? 113 ARG A CZ    1 
ATOM   921  N  NH1   . ARG A 1 113 ? 31.57700  52.13900  35.95700  1.000 358.51000 ? 113 ARG A NH1   1 
ATOM   922  N  NH2   . ARG A 1 113 ? 33.79200  51.99400  36.55100  1.000 358.70000 ? 113 ARG A NH2   1 
ATOM   923  N  N     . THR A 1 114 ? 31.52200  46.86100  40.65700  1.000 342.49000 ? 114 THR A N     1 
ATOM   924  C  CA    . THR A 1 114 ? 31.75400  45.42900  40.48900  1.000 346.61000 ? 114 THR A CA    1 
ATOM   925  C  C     . THR A 1 114 ? 31.11600  44.63800  41.61400  1.000 339.98000 ? 114 THR A C     1 
ATOM   926  O  O     . THR A 1 114 ? 30.18000  43.86100  41.39000  1.000 335.26000 ? 114 THR A O     1 
ATOM   927  C  CB    . THR A 1 114 ? 33.25300  45.11400  40.42300  1.000 356.14000 ? 114 THR A CB    1 
ATOM   928  O  OG1   . THR A 1 114 ? 33.76300  45.44600  39.12600  1.000 368.97000 ? 114 THR A OG1   1 
ATOM   929  C  CG2   . THR A 1 114 ? 33.51300  43.62300  40.69500  1.000 351.21000 ? 114 THR A CG2   1 
ATOM   930  N  N     . TYR A 1 115 ? 31.62000  44.81900  42.83300  1.000 344.50000 ? 115 TYR A N     1 
ATOM   931  C  CA    . TYR A 1 115 ? 31.18600  43.97700  43.93100  1.000 347.62000 ? 115 TYR A CA    1 
ATOM   932  C  C     . TYR A 1 115 ? 29.66300  43.86500  43.99900  1.000 347.93000 ? 115 TYR A C     1 
ATOM   933  O  O     . TYR A 1 115 ? 29.15000  42.82300  44.42500  1.000 352.65000 ? 115 TYR A O     1 
ATOM   934  C  CB    . TYR A 1 115 ? 31.78600  44.52100  45.23000  1.000 350.73000 ? 115 TYR A CB    1 
ATOM   935  C  CG    . TYR A 1 115 ? 31.17900  43.93900  46.48600  1.000 353.41000 ? 115 TYR A CG    1 
ATOM   936  C  CD1   . TYR A 1 115 ? 30.02700  44.49700  47.04000  1.000 355.48000 ? 115 TYR A CD1   1 
ATOM   937  C  CD2   . TYR A 1 115 ? 31.74800  42.83700  47.12400  1.000 347.06000 ? 115 TYR A CD2   1 
ATOM   938  C  CE1   . TYR A 1 115 ? 29.45200  43.98000  48.17700  1.000 351.65000 ? 115 TYR A CE1   1 
ATOM   939  C  CE2   . TYR A 1 115 ? 31.17300  42.30900  48.27900  1.000 344.41000 ? 115 TYR A CE2   1 
ATOM   940  C  CZ    . TYR A 1 115 ? 30.02500  42.89200  48.79400  1.000 344.99000 ? 115 TYR A CZ    1 
ATOM   941  O  OH    . TYR A 1 115 ? 29.42800  42.40100  49.92900  1.000 351.33000 ? 115 TYR A OH    1 
ATOM   942  N  N     . ASP A 1 116 ? 28.92900  44.87300  43.50500  1.000 342.46000 ? 116 ASP A N     1 
ATOM   943  C  CA    . ASP A 1 116 ? 27.48400  44.93300  43.71500  1.000 341.25000 ? 116 ASP A CA    1 
ATOM   944  C  C     . ASP A 1 116 ? 26.68100  44.20600  42.64700  1.000 338.26000 ? 116 ASP A C     1 
ATOM   945  O  O     . ASP A 1 116 ? 25.71200  43.51500  42.97100  1.000 341.55000 ? 116 ASP A O     1 
ATOM   946  C  CB    . ASP A 1 116 ? 27.03200  46.38400  43.80400  1.000 338.50000 ? 116 ASP A CB    1 
ATOM   947  C  CG    . ASP A 1 116 ? 27.08400  46.91000  45.21900  1.000 345.18000 ? 116 ASP A CG    1 
ATOM   948  O  OD1   . ASP A 1 116 ? 26.26600  46.46600  46.04800  1.000 352.97000 ? 116 ASP A OD1   1 
ATOM   949  O  OD2   . ASP A 1 116 ? 27.96500  47.74000  45.50500  1.000 345.06000 ? 116 ASP A OD2   1 
ATOM   950  N  N     . LEU A 1 117 ? 27.03000  44.36400  41.37600  1.000 334.35000 ? 117 LEU A N     1 
ATOM   951  C  CA    . LEU A 1 117 ? 26.47000  43.46800  40.37900  1.000 330.27000 ? 117 LEU A CA    1 
ATOM   952  C  C     . LEU A 1 117 ? 26.74800  42.02000  40.75200  1.000 334.74000 ? 117 LEU A C     1 
ATOM   953  O  O     . LEU A 1 117 ? 25.86200  41.16600  40.64000  1.000 334.18000 ? 117 LEU A O     1 
ATOM   954  C  CB    . LEU A 1 117 ? 27.03900  43.80600  39.00800  1.000 327.21000 ? 117 LEU A CB    1 
ATOM   955  C  CG    . LEU A 1 117 ? 26.62800  45.20400  38.54800  1.000 333.28000 ? 117 LEU A CG    1 
ATOM   956  C  CD1   . LEU A 1 117 ? 27.66200  45.74400  37.57600  1.000 335.74000 ? 117 LEU A CD1   1 
ATOM   957  C  CD2   . LEU A 1 117 ? 25.23700  45.15300  37.91700  1.000 333.12000 ? 117 LEU A CD2   1 
ATOM   958  N  N     . VAL A 1 118 ? 27.96400  41.73000  41.23500  1.000 337.81000 ? 118 VAL A N     1 
ATOM   959  C  CA    . VAL A 1 118 ? 28.28900  40.36500  41.65800  1.000 343.62000 ? 118 VAL A CA    1 
ATOM   960  C  C     . VAL A 1 118 ? 27.32700  39.91400  42.75200  1.000 343.18000 ? 118 VAL A C     1 
ATOM   961  O  O     . VAL A 1 118 ? 26.75500  38.81700  42.68800  1.000 341.76000 ? 118 VAL A O     1 
ATOM   962  C  CB    . VAL A 1 118 ? 29.76300  40.25700  42.10400  1.000 341.87000 ? 118 VAL A CB    1 
ATOM   963  C  CG1   . VAL A 1 118 ? 30.10000  38.83500  42.60200  1.000 338.31000 ? 118 VAL A CG1   1 
ATOM   964  C  CG2   . VAL A 1 118 ? 30.71400  40.67100  40.98400  1.000 331.02000 ? 118 VAL A CG2   1 
ATOM   965  N  N     . THR A 1 119 ? 27.10000  40.77000  43.75400  1.000 344.74000 ? 119 THR A N     1 
ATOM   966  C  CA    . THR A 1 119 ? 26.12500  40.41800  44.77900  1.000 338.99000 ? 119 THR A CA    1 
ATOM   967  C  C     . THR A 1 119 ? 24.72000  40.32900  44.18900  1.000 336.70000 ? 119 THR A C     1 
ATOM   968  O  O     . THR A 1 119 ? 23.91800  39.50700  44.64000  1.000 333.23000 ? 119 THR A O     1 
ATOM   969  C  CB    . THR A 1 119 ? 26.17500  41.40800  45.95700  1.000 336.59000 ? 119 THR A CB    1 
ATOM   970  O  OG1   . THR A 1 119 ? 27.53300  41.60500  46.36900  1.000 340.56000 ? 119 THR A OG1   1 
ATOM   971  C  CG2   . THR A 1 119 ? 25.39800  40.84800  47.13500  1.000 335.24000 ? 119 THR A CG2   1 
ATOM   972  N  N     . LEU A 1 120 ? 24.40300  41.15300  43.17800  1.000 333.95000 ? 120 LEU A N     1 
ATOM   973  C  CA    . LEU A 1 120 ? 23.11800  41.01800  42.48600  1.000 327.24000 ? 120 LEU A CA    1 
ATOM   974  C  C     . LEU A 1 120 ? 22.94100  39.61300  41.92700  1.000 326.41000 ? 120 LEU A C     1 
ATOM   975  O  O     . LEU A 1 120 ? 21.98100  38.91000  42.27100  1.000 332.40000 ? 120 LEU A O     1 
ATOM   976  C  CB    . LEU A 1 120 ? 22.98400  42.04700  41.36800  1.000 315.61000 ? 120 LEU A CB    1 
ATOM   977  C  CG    . LEU A 1 120 ? 21.98300  41.89400  40.22800  1.000 310.58000 ? 120 LEU A CG    1 
ATOM   978  C  CD1   . LEU A 1 120 ? 20.56400  41.64900  40.76400  1.000 310.99000 ? 120 LEU A CD1   1 
ATOM   979  C  CD2   . LEU A 1 120 ? 22.03900  43.11300  39.28400  1.000 323.15000 ? 120 LEU A CD2   1 
ATOM   980  N  N     . PHE A 1 121 ? 23.86600  39.17600  41.07200  1.000 325.14000 ? 121 PHE A N     1 
ATOM   981  C  CA    . PHE A 1 121 ? 23.71300  37.86200  40.45200  1.000 326.68000 ? 121 PHE A CA    1 
ATOM   982  C  C     . PHE A 1 121 ? 23.62700  36.75300  41.49300  1.000 330.21000 ? 121 PHE A C     1 
ATOM   983  O  O     . PHE A 1 121 ? 22.77100  35.86800  41.38600  1.000 333.99000 ? 121 PHE A O     1 
ATOM   984  C  CB    . PHE A 1 121 ? 24.87000  37.57800  39.48500  1.000 332.06000 ? 121 PHE A CB    1 
ATOM   985  C  CG    . PHE A 1 121 ? 24.76500  38.30500  38.14500  1.000 330.73000 ? 121 PHE A CG    1 
ATOM   986  C  CD1   . PHE A 1 121 ? 24.19900  37.69400  37.02200  1.000 323.46000 ? 121 PHE A CD1   1 
ATOM   987  C  CD2   . PHE A 1 121 ? 25.27300  39.58300  38.01100  1.000 329.00000 ? 121 PHE A CD2   1 
ATOM   988  C  CE1   . PHE A 1 121 ? 24.12700  38.36800  35.80900  1.000 318.81000 ? 121 PHE A CE1   1 
ATOM   989  C  CE2   . PHE A 1 121 ? 25.20100  40.25100  36.81300  1.000 323.38000 ? 121 PHE A CE2   1 
ATOM   990  C  CZ    . PHE A 1 121 ? 24.62000  39.65000  35.71500  1.000 319.67000 ? 121 PHE A CZ    1 
ATOM   991  N  N     . ASN A 1 122 ? 24.48400  36.79000  42.51500  1.000 332.42000 ? 122 ASN A N     1 
ATOM   992  C  CA    . ASN A 1 122 ? 24.47300  35.71800  43.50300  1.000 335.23000 ? 122 ASN A CA    1 
ATOM   993  C  C     . ASN A 1 122 ? 23.11800  35.60700  44.18300  1.000 337.71000 ? 122 ASN A C     1 
ATOM   994  O  O     . ASN A 1 122 ? 22.51100  34.53000  44.19500  1.000 343.12000 ? 122 ASN A O     1 
ATOM   995  C  CB    . ASN A 1 122 ? 25.58500  35.95300  44.51500  1.000 332.09000 ? 122 ASN A CB    1 
ATOM   996  C  CG    . ASN A 1 122 ? 26.93200  36.08600  43.84900  1.000 331.56000 ? 122 ASN A CG    1 
ATOM   997  O  OD1   . ASN A 1 122 ? 27.03300  36.00900  42.62700  1.000 326.49000 ? 122 ASN A OD1   1 
ATOM   998  N  ND2   . ASN A 1 122 ? 27.97300  36.29000  44.64400  1.000 334.29000 ? 122 ASN A ND2   1 
ATOM   999  N  N     . ASP A 1 123 ? 22.61300  36.71300  44.72400  1.000 330.24000 ? 123 ASP A N     1 
ATOM   1000 C  CA    . ASP A 1 123 ? 21.26500  36.69100  45.25700  1.000 328.29000 ? 123 ASP A CA    1 
ATOM   1001 C  C     . ASP A 1 123 ? 20.30200  36.11000  44.23900  1.000 339.43000 ? 123 ASP A C     1 
ATOM   1002 O  O     . ASP A 1 123 ? 19.54700  35.18900  44.55600  1.000 338.70000 ? 123 ASP A O     1 
ATOM   1003 C  CB    . ASP A 1 123 ? 20.85600  38.09800  45.68600  1.000 331.49000 ? 123 ASP A CB    1 
ATOM   1004 C  CG    . ASP A 1 123 ? 20.57700  38.15800  47.13200  1.000 335.72000 ? 123 ASP A CG    1 
ATOM   1005 O  OD1   . ASP A 1 123 ? 21.55100  38.19000  47.90100  1.000 332.48000 ? 123 ASP A OD1   1 
ATOM   1006 O  OD2   . ASP A 1 123 ? 19.38900  38.10200  47.48900  1.000 338.14000 ? 123 ASP A OD2   1 
ATOM   1007 N  N     . LYS A 1 124 ? 20.38400  36.56200  42.98400  1.000 344.33000 ? 124 LYS A N     1 
ATOM   1008 C  CA    . LYS A 1 124 ? 19.54300  35.97200  41.94300  1.000 340.80000 ? 124 LYS A CA    1 
ATOM   1009 C  C     . LYS A 1 124 ? 19.81300  34.48100  41.78900  1.000 339.08000 ? 124 LYS A C     1 
ATOM   1010 O  O     . LYS A 1 124 ? 18.87600  33.68800  41.61000  1.000 336.22000 ? 124 LYS A O     1 
ATOM   1011 C  CB    . LYS A 1 124 ? 19.76000  36.68800  40.60800  1.000 330.65000 ? 124 LYS A CB    1 
ATOM   1012 C  CG    . LYS A 1 124 ? 19.24000  38.12900  40.53300  1.000 334.11000 ? 124 LYS A CG    1 
ATOM   1013 C  CD    . LYS A 1 124 ? 17.69400  38.17100  40.58400  1.000 345.31000 ? 124 LYS A CD    1 
ATOM   1014 C  CE    . LYS A 1 124 ? 17.13300  39.47800  41.18600  1.000 346.70000 ? 124 LYS A CE    1 
ATOM   1015 N  NZ    . LYS A 1 124 ? 15.88800  39.23200  41.99400  1.000 341.94000 ? 124 LYS A NZ    1 
ATOM   1016 N  N     . ILE A 1 125 ? 21.09200  34.09200  41.84000  1.000 343.41000 ? 125 ILE A N     1 
ATOM   1017 C  CA    . ILE A 1 125 ? 21.45100  32.67500  41.79500  1.000 345.40000 ? 125 ILE A CA    1 
ATOM   1018 C  C     . ILE A 1 125 ? 21.04800  31.99200  43.11100  1.000 346.43000 ? 125 ILE A C     1 
ATOM   1019 O  O     . ILE A 1 125 ? 20.22900  31.06000  43.13200  1.000 348.31000 ? 125 ILE A O     1 
ATOM   1020 C  CB    . ILE A 1 125 ? 22.96300  32.50100  41.48500  1.000 338.91000 ? 125 ILE A CB    1 
ATOM   1021 C  CG1   . ILE A 1 125 ? 23.34400  33.10600  40.14200  1.000 329.95000 ? 125 ILE A CG1   1 
ATOM   1022 C  CG2   . ILE A 1 125 ? 23.37500  31.02700  41.44100  1.000 331.27000 ? 125 ILE A CG2   1 
ATOM   1023 C  CD1   . ILE A 1 125 ? 24.76100  32.76600  39.61100  1.000 314.21000 ? 125 ILE A CD1   1 
ATOM   1024 N  N     . ILE A 1 126 ? 21.59400  32.47700  44.23700  1.000 342.37000 ? 126 ILE A N     1 
ATOM   1025 C  CA    . ILE A 1 126 ? 21.41000  31.81500  45.53600  1.000 326.58000 ? 126 ILE A CA    1 
ATOM   1026 C  C     . ILE A 1 126 ? 19.93800  31.70900  45.88200  1.000 330.63000 ? 126 ILE A C     1 
ATOM   1027 O  O     . ILE A 1 126 ? 19.47700  30.66300  46.36200  1.000 332.68000 ? 126 ILE A O     1 
ATOM   1028 C  CB    . ILE A 1 126 ? 22.18600  32.54200  46.65500  1.000 324.54000 ? 126 ILE A CB    1 
ATOM   1029 C  CG1   . ILE A 1 126 ? 23.69100  32.47600  46.41900  1.000 318.95000 ? 126 ILE A CG1   1 
ATOM   1030 C  CG2   . ILE A 1 126 ? 21.89200  31.91200  47.98600  1.000 326.34000 ? 126 ILE A CG2   1 
ATOM   1031 C  CD1   . ILE A 1 126 ? 24.46900  33.53300  47.19700  1.000 320.84000 ? 126 ILE A CD1   1 
ATOM   1032 N  N     . THR A 1 127 ? 19.17700  32.78900  45.65400  1.000 335.68000 ? 127 THR A N     1 
ATOM   1033 C  CA    . THR A 1 127 ? 17.73000  32.69900  45.82600  1.000 346.00000 ? 127 THR A CA    1 
ATOM   1034 C  C     . THR A 1 127 ? 17.16700  31.56700  44.99200  1.000 351.80000 ? 127 THR A C     1 
ATOM   1035 O  O     . THR A 1 127 ? 16.40100  30.74400  45.49000  1.000 363.81000 ? 127 THR A O     1 
ATOM   1036 C  CB    . THR A 1 127 ? 17.00400  33.99100  45.44500  1.000 345.53000 ? 127 THR A CB    1 
ATOM   1037 O  OG1   . THR A 1 127 ? 17.45000  34.43800  44.15900  1.000 340.86000 ? 127 THR A OG1   1 
ATOM   1038 C  CG2   . THR A 1 127 ? 17.18100  35.08700  46.51000  1.000 342.93000 ? 127 THR A CG2   1 
ATOM   1039 N  N     . ALA A 1 128 ? 17.52100  31.50100  43.71900  1.000 340.55000 ? 128 ALA A N     1 
ATOM   1040 C  CA    . ALA A 1 128 ? 17.00500  30.38700  42.93600  1.000 338.71000 ? 128 ALA A CA    1 
ATOM   1041 C  C     . ALA A 1 128 ? 17.54300  29.05300  43.44800  1.000 344.99000 ? 128 ALA A C     1 
ATOM   1042 O  O     . ALA A 1 128 ? 16.78500  28.10100  43.60800  1.000 352.44000 ? 128 ALA A O     1 
ATOM   1043 C  CB    . ALA A 1 128 ? 17.30400  30.59200  41.45900  1.000 333.67000 ? 128 ALA A CB    1 
ATOM   1044 N  N     . ASN A 1 129 ? 18.83400  28.96700  43.76400  1.000 343.48000 ? 129 ASN A N     1 
ATOM   1045 C  CA    . ASN A 1 129 ? 19.38700  27.66800  44.16300  1.000 347.76000 ? 129 ASN A CA    1 
ATOM   1046 C  C     . ASN A 1 129 ? 18.85200  27.22100  45.52000  1.000 349.18000 ? 129 ASN A C     1 
ATOM   1047 O  O     . ASN A 1 129 ? 18.29900  26.12000  45.64600  1.000 358.22000 ? 129 ASN A O     1 
ATOM   1048 C  CB    . ASN A 1 129 ? 20.91100  27.69700  44.17800  1.000 346.45000 ? 129 ASN A CB    1 
ATOM   1049 C  CG    . ASN A 1 129 ? 21.51600  26.46700  44.85600  1.000 345.24000 ? 129 ASN A CG    1 
ATOM   1050 O  OD1   . ASN A 1 129 ? 21.90700  26.53300  46.01700  1.000 342.08000 ? 129 ASN A OD1   1 
ATOM   1051 N  ND2   . ASN A 1 129 ? 21.60800  25.34800  44.12500  1.000 347.54000 ? 129 ASN A ND2   1 
ATOM   1052 N  N     . LYS A 1 130 ? 18.99300  28.06600  46.54200  1.000 337.36000 ? 130 LYS A N     1 
ATOM   1053 C  CA    . LYS A 1 130 ? 18.56700  27.69200  47.88500  1.000 343.52000 ? 130 LYS A CA    1 
ATOM   1054 C  C     . LYS A 1 130 ? 17.05800  27.48300  47.96200  1.000 344.23000 ? 130 LYS A C     1 
ATOM   1055 O  O     . LYS A 1 130 ? 16.58600  26.44400  48.44900  1.000 343.79000 ? 130 LYS A O     1 
ATOM   1056 C  CB    . LYS A 1 130 ? 19.02300  28.76000  48.87100  1.000 346.81000 ? 130 LYS A CB    1 
ATOM   1057 C  CG    . LYS A 1 130 ? 18.62200  28.46900  50.27400  1.000 342.40000 ? 130 LYS A CG    1 
ATOM   1058 C  CD    . LYS A 1 130 ? 19.42900  29.27000  51.23100  1.000 333.97000 ? 130 LYS A CD    1 
ATOM   1059 C  CE    . LYS A 1 130 ? 19.20400  28.74000  52.60900  1.000 338.95000 ? 130 LYS A CE    1 
ATOM   1060 N  NZ    . LYS A 1 130 ? 19.25300  27.24900  52.57300  1.000 329.96000 ? 130 LYS A NZ    1 
ATOM   1061 N  N     . ASN A 1 131 ? 16.28300  28.45800  47.47400  1.000 356.54000 ? 131 ASN A N     1 
ATOM   1062 C  CA    . ASN A 1 131 ? 14.82600  28.41400  47.65900  1.000 361.32000 ? 131 ASN A CA    1 
ATOM   1063 C  C     . ASN A 1 131 ? 14.14600  27.32100  46.81700  1.000 370.14000 ? 131 ASN A C     1 
ATOM   1064 O  O     . ASN A 1 131 ? 13.19400  26.68800  47.28000  1.000 365.87000 ? 131 ASN A O     1 
ATOM   1065 C  CB    . ASN A 1 131 ? 14.20800  29.78600  47.34000  1.000 371.74000 ? 131 ASN A CB    1 
ATOM   1066 C  CG    . ASN A 1 131 ? 13.62500  30.48000  48.57600  1.000 362.55000 ? 131 ASN A CG    1 
ATOM   1067 O  OD1   . ASN A 1 131 ? 14.11000  30.30100  49.69000  1.000 356.02000 ? 131 ASN A OD1   1 
ATOM   1068 N  ND2   . ASN A 1 131 ? 12.58200  31.30300  48.36800  1.000 359.64000 ? 131 ASN A ND2   1 
ATOM   1069 N  N     . ASP A 1 132 ? 14.64200  27.08600  45.59300  1.000 371.14000 ? 132 ASP A N     1 
ATOM   1070 C  CA    . ASP A 1 132 ? 14.03400  26.21700  44.57300  1.000 372.51000 ? 132 ASP A CA    1 
ATOM   1071 C  C     . ASP A 1 132 ? 13.88300  24.80900  45.04400  1.000 367.62000 ? 132 ASP A C     1 
ATOM   1072 O  O     . ASP A 1 132 ? 14.86900  24.20400  45.45400  1.000 356.93000 ? 132 ASP A O     1 
ATOM   1073 C  CB    . ASP A 1 132 ? 14.84000  26.16900  43.26000  1.000 367.98000 ? 132 ASP A CB    1 
ATOM   1074 C  CG    . ASP A 1 132 ? 13.94600  26.63500  42.01800  1.000 364.89000 ? 132 ASP A CG    1 
ATOM   1075 O  OD1   . ASP A 1 132 ? 13.03900  27.41700  42.24000  1.000 356.54000 ? 132 ASP A OD1   1 
ATOM   1076 O  OD2   . ASP A 1 132 ? 14.07400  26.25700  40.86800  1.000 369.03000 ? 132 ASP A OD2   1 
ATOM   1077 N  N     . GLU A 1 133 ? 12.62700  24.33000  45.02600  1.000 367.60000 ? 133 GLU A N     1 
ATOM   1078 C  CA    . GLU A 1 133 ? 12.32200  22.91100  44.96300  1.000 361.88000 ? 133 GLU A CA    1 
ATOM   1079 C  C     . GLU A 1 133 ? 12.91000  22.29700  43.72100  1.000 362.81000 ? 133 GLU A C     1 
ATOM   1080 O  O     . GLU A 1 133 ? 13.67500  21.32900  43.80500  1.000 356.79000 ? 133 GLU A O     1 
ATOM   1081 C  CB    . GLU A 1 133 ? 10.79200  22.74900  45.01000  1.000 364.44000 ? 133 GLU A CB    1 
ATOM   1082 C  CG    . GLU A 1 133 ? 9.94300   23.25400  43.74200  1.000 364.98000 ? 133 GLU A CG    1 
ATOM   1083 C  CD    . GLU A 1 133 ? 10.06900  24.74800  43.34500  1.000 361.37000 ? 133 GLU A CD    1 
ATOM   1084 O  OE1   . GLU A 1 133 ? 10.82100  25.51400  43.98100  1.000 371.15000 ? 133 GLU A OE1   1 
ATOM   1085 O  OE2   . GLU A 1 133 ? 9.38400   25.14500  42.37300  1.000 358.23000 ? 133 GLU A OE2   1 
ATOM   1086 N  N     . GLU A 1 134 ? 12.50700  22.80600  42.56300  1.000 370.64000 ? 134 GLU A N     1 
ATOM   1087 C  CA    . GLU A 1 134 ? 13.16400  22.41600  41.31900  1.000 374.10000 ? 134 GLU A CA    1 
ATOM   1088 C  C     . GLU A 1 134 ? 14.66400  22.58300  41.37600  1.000 371.03000 ? 134 GLU A C     1 
ATOM   1089 O  O     . GLU A 1 134 ? 15.20700  23.37700  42.10600  1.000 369.23000 ? 134 GLU A O     1 
ATOM   1090 C  CB    . GLU A 1 134 ? 12.65500  23.25300  40.13200  1.000 370.55000 ? 134 GLU A CB    1 
ATOM   1091 C  CG    . GLU A 1 134 ? 11.11200  23.43800  39.98900  1.000 364.76000 ? 134 GLU A CG    1 
ATOM   1092 C  CD    . GLU A 1 134 ? 10.43400  22.70400  38.82300  1.000 360.79000 ? 134 GLU A CD    1 
ATOM   1093 O  OE1   . GLU A 1 134 ? 10.36600  23.25900  37.71400  1.000 360.68000 ? 134 GLU A OE1   1 
ATOM   1094 O  OE2   . GLU A 1 134 ? 9.92000   21.59800  39.02900  1.000 364.92000 ? 134 GLU A OE2   1 
ATOM   1095 N  N     . ARG A 1 135 ? 15.32400  21.82300  40.57800  1.000 364.70000 ? 135 ARG A N     1 
ATOM   1096 C  CA    . ARG A 1 135 ? 16.76500  21.67400  40.63600  1.000 345.47000 ? 135 ARG A CA    1 
ATOM   1097 C  C     . ARG A 1 135 ? 17.41800  21.96000  39.27500  1.000 331.72000 ? 135 ARG A C     1 
ATOM   1098 O  O     . ARG A 1 135 ? 17.04600  21.38200  38.23900  1.000 328.91000 ? 135 ARG A O     1 
ATOM   1099 C  CB    . ARG A 1 135 ? 17.16100  20.26800  41.14000  1.000 346.35000 ? 135 ARG A CB    1 
ATOM   1100 C  CG    . ARG A 1 135 ? 16.73400  20.08800  42.62100  1.000 337.99000 ? 135 ARG A CG    1 
ATOM   1101 C  CD    . ARG A 1 135 ? 17.02900  21.31800  43.50800  1.000 331.19000 ? 135 ARG A CD    1 
ATOM   1102 N  NE    . ARG A 1 135 ? 18.42800  21.37500  43.91800  1.000 331.82000 ? 135 ARG A NE    1 
ATOM   1103 C  CZ    . ARG A 1 135 ? 18.95300  22.30800  44.70600  1.000 324.86000 ? 135 ARG A CZ    1 
ATOM   1104 N  NH1   . ARG A 1 135 ? 18.19500  23.28700  45.18000  1.000 326.44000 ? 135 ARG A NH1   1 
ATOM   1105 N  NH2   . ARG A 1 135 ? 20.24200  22.25500  45.01900  1.000 319.59000 ? 135 ARG A NH2   1 
ATOM   1106 N  N     . VAL A 1 136 ? 18.44800  22.80200  39.30300  1.000 315.76000 ? 136 VAL A N     1 
ATOM   1107 C  CA    . VAL A 1 136 ? 19.20800  23.20000  38.13300  1.000 312.17000 ? 136 VAL A CA    1 
ATOM   1108 C  C     . VAL A 1 136 ? 20.58900  22.59100  38.28200  1.000 313.49000 ? 136 VAL A C     1 
ATOM   1109 O  O     . VAL A 1 136 ? 21.14200  22.56300  39.39000  1.000 309.03000 ? 136 VAL A O     1 
ATOM   1110 C  CB    . VAL A 1 136 ? 19.25200  24.72900  38.02300  1.000 306.20000 ? 136 VAL A CB    1 
ATOM   1111 C  CG1   . VAL A 1 136 ? 19.63300  25.10500  36.67700  1.000 304.43000 ? 136 VAL A CG1   1 
ATOM   1112 C  CG2   . VAL A 1 136 ? 17.88200  25.31700  38.42700  1.000 310.91000 ? 136 VAL A CG2   1 
ATOM   1113 N  N     . ASP A 1 137 ? 21.06900  21.98400  37.19700  1.000 319.90000 ? 137 ASP A N     1 
ATOM   1114 C  CA    . ASP A 1 137 ? 22.36000  21.30900  37.19900  1.000 317.08000 ? 137 ASP A CA    1 
ATOM   1115 C  C     . ASP A 1 137 ? 23.50300  22.32300  37.09400  1.000 307.62000 ? 137 ASP A C     1 
ATOM   1116 O  O     . ASP A 1 137 ? 24.44700  22.27800  37.89200  1.000 299.85000 ? 137 ASP A O     1 
ATOM   1117 C  CB    . ASP A 1 137 ? 22.38300  20.28200  36.05200  1.000 316.15000 ? 137 ASP A CB    1 
ATOM   1118 C  CG    . ASP A 1 137 ? 21.60900  18.97300  36.38200  1.000 308.71000 ? 137 ASP A CG    1 
ATOM   1119 O  OD1   . ASP A 1 137 ? 22.22400  17.87100  36.30700  1.000 308.26000 ? 137 ASP A OD1   1 
ATOM   1120 O  OD2   . ASP A 1 137 ? 20.39200  19.01600  36.70800  1.000 316.32000 ? 137 ASP A OD2   1 
ATOM   1121 N  N     . VAL A 1 138 ? 23.41700  23.28400  36.16100  1.000 310.36000 ? 138 VAL A N     1 
ATOM   1122 C  CA    . VAL A 1 138 ? 24.41500  24.34900  36.06600  1.000 297.91000 ? 138 VAL A CA    1 
ATOM   1123 C  C     . VAL A 1 138 ? 23.73300  25.70700  35.94400  1.000 297.30000 ? 138 VAL A C     1 
ATOM   1124 O  O     . VAL A 1 138 ? 22.72400  25.85400  35.24500  1.000 300.41000 ? 138 VAL A O     1 
ATOM   1125 C  CB    . VAL A 1 138 ? 25.38800  24.13700  34.89400  1.000 287.58000 ? 138 VAL A CB    1 
ATOM   1126 C  CG1   . VAL A 1 138 ? 26.38500  25.30700  34.81700  1.000 290.21000 ? 138 VAL A CG1   1 
ATOM   1127 C  CG2   . VAL A 1 138 ? 26.11000  22.83000  35.04500  1.000 286.80000 ? 138 VAL A CG2   1 
ATOM   1128 N  N     . TRP A 1 139 ? 24.27900  26.70000  36.65600  1.000 301.03000 ? 139 TRP A N     1 
ATOM   1129 C  CA    . TRP A 1 139 ? 23.85100  28.09300  36.54100  1.000 301.47000 ? 139 TRP A CA    1 
ATOM   1130 C  C     . TRP A 1 139 ? 24.76300  28.78400  35.54500  1.000 295.45000 ? 139 TRP A C     1 
ATOM   1131 O  O     . TRP A 1 139 ? 25.99300  28.74500  35.67200  1.000 292.65000 ? 139 TRP A O     1 
ATOM   1132 C  CB    . TRP A 1 139 ? 23.86500  28.83700  37.88100  1.000 305.67000 ? 139 TRP A CB    1 
ATOM   1133 C  CG    . TRP A 1 139 ? 22.59200  28.65800  38.61000  1.000 309.30000 ? 139 TRP A CG    1 
ATOM   1134 C  CD1   . TRP A 1 139 ? 22.39100  27.93400  39.74000  1.000 315.57000 ? 139 TRP A CD1   1 
ATOM   1135 C  CD2   . TRP A 1 139 ? 21.31600  29.16800  38.22600  1.000 305.59000 ? 139 TRP A CD2   1 
ATOM   1136 N  NE1   . TRP A 1 139 ? 21.06500  27.97800  40.10000  1.000 315.96000 ? 139 TRP A NE1   1 
ATOM   1137 C  CE2   . TRP A 1 139 ? 20.38700  28.73200  39.18000  1.000 307.94000 ? 139 TRP A CE2   1 
ATOM   1138 C  CE3   . TRP A 1 139 ? 20.87300  29.96800  37.17700  1.000 305.83000 ? 139 TRP A CE3   1 
ATOM   1139 C  CZ2   . TRP A 1 139 ? 19.04400  29.05800  39.10400  1.000 311.75000 ? 139 TRP A CZ2   1 
ATOM   1140 C  CZ3   . TRP A 1 139 ? 19.54200  30.31000  37.11700  1.000 305.43000 ? 139 TRP A CZ3   1 
ATOM   1141 C  CH2   . TRP A 1 139 ? 18.64100  29.84600  38.06000  1.000 311.13000 ? 139 TRP A CH2   1 
ATOM   1142 N  N     . PHE A 1 140 ? 24.15300  29.39300  34.55400  1.000 290.92000 ? 140 PHE A N     1 
ATOM   1143 C  CA    . PHE A 1 140 ? 24.84900  29.99700  33.43900  1.000 289.53000 ? 140 PHE A CA    1 
ATOM   1144 C  C     . PHE A 1 140 ? 24.68100  31.49600  33.56700  1.000 286.13000 ? 140 PHE A C     1 
ATOM   1145 O  O     . PHE A 1 140 ? 23.56800  32.01800  33.47600  1.000 289.54000 ? 140 PHE A O     1 
ATOM   1146 C  CB    . PHE A 1 140 ? 24.28400  29.47200  32.12300  1.000 291.39000 ? 140 PHE A CB    1 
ATOM   1147 C  CG    . PHE A 1 140 ? 24.32900  27.96800  32.01800  1.000 293.52000 ? 140 PHE A CG    1 
ATOM   1148 C  CD1   . PHE A 1 140 ? 25.29700  27.34500  31.24000  1.000 302.22000 ? 140 PHE A CD1   1 
ATOM   1149 C  CD2   . PHE A 1 140 ? 23.43400  27.16500  32.72200  1.000 294.46000 ? 140 PHE A CD2   1 
ATOM   1150 C  CE1   . PHE A 1 140 ? 25.35900  25.96100  31.15700  1.000 300.31000 ? 140 PHE A CE1   1 
ATOM   1151 C  CE2   . PHE A 1 140 ? 23.50300  25.77100  32.61200  1.000 292.38000 ? 140 PHE A CE2   1 
ATOM   1152 C  CZ    . PHE A 1 140 ? 24.46500  25.16700  31.84000  1.000 293.08000 ? 140 PHE A CZ    1 
ATOM   1153 N  N     . VAL A 1 141 ? 25.76800  32.17400  33.84200  1.000 289.14000 ? 141 VAL A N     1 
ATOM   1154 C  CA    . VAL A 1 141 ? 25.75900  33.61400  33.97800  1.000 290.00000 ? 141 VAL A CA    1 
ATOM   1155 C  C     . VAL A 1 141 ? 25.95200  34.17200  32.57200  1.000 296.05000 ? 141 VAL A C     1 
ATOM   1156 O  O     . VAL A 1 141 ? 27.03700  34.03600  32.00700  1.000 302.55000 ? 141 VAL A O     1 
ATOM   1157 C  CB    . VAL A 1 141 ? 26.85600  34.05000  34.95000  1.000 289.25000 ? 141 VAL A CB    1 
ATOM   1158 C  CG1   . VAL A 1 141 ? 26.69900  35.51300  35.31500  1.000 300.43000 ? 141 VAL A CG1   1 
ATOM   1159 C  CG2   . VAL A 1 141 ? 26.79400  33.15500  36.18900  1.000 294.14000 ? 141 VAL A CG2   1 
ATOM   1160 N  N     . ILE A 1 142 ? 24.90000  34.70300  31.94000  1.000 295.55000 ? 142 ILE A N     1 
ATOM   1161 C  CA    . ILE A 1 142 ? 24.98500  35.22700  30.56700  1.000 301.45000 ? 142 ILE A CA    1 
ATOM   1162 C  C     . ILE A 1 142 ? 25.21900  36.73500  30.65000  1.000 309.09000 ? 142 ILE A C     1 
ATOM   1163 O  O     . ILE A 1 142 ? 24.26300  37.50600  30.74700  1.000 307.21000 ? 142 ILE A O     1 
ATOM   1164 C  CB    . ILE A 1 142 ? 23.72500  34.92700  29.75300  1.000 298.84000 ? 142 ILE A CB    1 
ATOM   1165 C  CG1   . ILE A 1 142 ? 23.11900  33.58500  30.12500  1.000 294.13000 ? 142 ILE A CG1   1 
ATOM   1166 C  CG2   . ILE A 1 142 ? 24.04400  35.02500  28.25600  1.000 301.15000 ? 142 ILE A CG2   1 
ATOM   1167 C  CD1   . ILE A 1 142 ? 23.99400  32.39300  29.85500  1.000 289.57000 ? 142 ILE A CD1   1 
ATOM   1168 N  N     . VAL A 1 143 ? 26.48600  37.14900  30.55400  1.000 319.01000 ? 143 VAL A N     1 
ATOM   1169 C  CA    . VAL A 1 143 ? 26.98000  38.51200  30.78200  1.000 315.65000 ? 143 VAL A CA    1 
ATOM   1170 C  C     . VAL A 1 143 ? 26.70800  39.39400  29.57500  1.000 312.51000 ? 143 VAL A C     1 
ATOM   1171 O  O     . VAL A 1 143 ? 27.37100  39.23100  28.52900  1.000 311.61000 ? 143 VAL A O     1 
ATOM   1172 C  CB    . VAL A 1 143 ? 28.48200  38.49400  31.11500  1.000 314.44000 ? 143 VAL A CB    1 
ATOM   1173 C  CG1   . VAL A 1 143 ? 29.12600  39.88100  30.96300  1.000 305.99000 ? 143 VAL A CG1   1 
ATOM   1174 C  CG2   . VAL A 1 143 ? 28.67900  37.97200  32.51100  1.000 315.38000 ? 143 VAL A CG2   1 
ATOM   1175 N  N     . PRO A 1 144 ? 25.72700  40.30200  29.65900  1.000 317.25000 ? 144 PRO A N     1 
ATOM   1176 C  CA    . PRO A 1 144 ? 25.67800  41.41100  28.69700  1.000 312.78000 ? 144 PRO A CA    1 
ATOM   1177 C  C     . PRO A 1 144 ? 27.00900  42.10600  28.57800  1.000 313.49000 ? 144 PRO A C     1 
ATOM   1178 O  O     . PRO A 1 144 ? 27.74400  42.24900  29.56000  1.000 315.10000 ? 144 PRO A O     1 
ATOM   1179 C  CB    . PRO A 1 144 ? 24.63100  42.37300  29.27000  1.000 309.54000 ? 144 PRO A CB    1 
ATOM   1180 C  CG    . PRO A 1 144 ? 23.80200  41.51300  30.11800  1.000 315.05000 ? 144 PRO A CG    1 
ATOM   1181 C  CD    . PRO A 1 144 ? 24.66400  40.41200  30.67500  1.000 317.67000 ? 144 PRO A CD    1 
ATOM   1182 N  N     . GLU A 1 145 ? 27.32100  42.51100  27.34000  1.000 308.43000 ? 145 GLU A N     1 
ATOM   1183 C  CA    . GLU A 1 145 ? 28.61200  43.14100  27.09100  1.000 313.32000 ? 145 GLU A CA    1 
ATOM   1184 C  C     . GLU A 1 145 ? 28.86700  44.28200  28.05200  1.000 309.81000 ? 145 GLU A C     1 
ATOM   1185 O  O     . GLU A 1 145 ? 29.98900  44.42200  28.57900  1.000 312.92000 ? 145 GLU A O     1 
ATOM   1186 C  CB    . GLU A 1 145 ? 28.65200  43.65000  25.64900  1.000 316.74000 ? 145 GLU A CB    1 
ATOM   1187 C  CG    . GLU A 1 145 ? 29.99300  44.23900  25.18900  1.000 320.64000 ? 145 GLU A CG    1 
ATOM   1188 C  CD    . GLU A 1 145 ? 30.85900  43.25200  24.40200  1.000 322.09000 ? 145 GLU A CD    1 
ATOM   1189 O  OE1   . GLU A 1 145 ? 30.42300  42.75800  23.33700  1.000 320.57000 ? 145 GLU A OE1   1 
ATOM   1190 O  OE2   . GLU A 1 145 ? 31.97200  42.94300  24.87500  1.000 319.73000 ? 145 GLU A OE2   1 
ATOM   1191 N  N     . GLU A 1 146 ? 27.82400  45.06900  28.32200  1.000 317.38000 ? 146 GLU A N     1 
ATOM   1192 C  CA    . GLU A 1 146 ? 27.98000  46.20100  29.21900  1.000 320.51000 ? 146 GLU A CA    1 
ATOM   1193 C  C     . GLU A 1 146 ? 28.67600  45.81800  30.52100  1.000 319.70000 ? 146 GLU A C     1 
ATOM   1194 O  O     . GLU A 1 146 ? 29.39700  46.64200  31.10400  1.000 322.12000 ? 146 GLU A O     1 
ATOM   1195 C  CB    . GLU A 1 146 ? 26.61300  46.79200  29.50000  1.000 314.61000 ? 146 GLU A CB    1 
ATOM   1196 C  CG    . GLU A 1 146 ? 25.52400  45.79100  29.26400  1.000 320.35000 ? 146 GLU A CG    1 
ATOM   1197 C  CD    . GLU A 1 146 ? 24.19100  46.45500  29.05800  1.000 326.83000 ? 146 GLU A CD    1 
ATOM   1198 O  OE1   . GLU A 1 146 ? 24.16300  47.57800  28.50000  1.000 341.68000 ? 146 GLU A OE1   1 
ATOM   1199 O  OE2   . GLU A 1 146 ? 23.16900  45.85300  29.45600  1.000 325.78000 ? 146 GLU A OE2   1 
ATOM   1200 N  N     . ILE A 1 147 ? 28.49200  44.57700  30.98300  1.000 324.36000 ? 147 ILE A N     1 
ATOM   1201 C  CA    . ILE A 1 147 ? 29.15000  44.14700  32.21500  1.000 329.60000 ? 147 ILE A CA    1 
ATOM   1202 C  C     . ILE A 1 147 ? 30.61900  43.86200  31.95600  1.000 326.08000 ? 147 ILE A C     1 
ATOM   1203 O  O     . ILE A 1 147 ? 31.50700  44.51200  32.52300  1.000 328.28000 ? 147 ILE A O     1 
ATOM   1204 C  CB    . ILE A 1 147 ? 28.45600  42.91400  32.83600  1.000 334.80000 ? 147 ILE A CB    1 
ATOM   1205 C  CG1   . ILE A 1 147 ? 26.94500  43.11400  32.94600  1.000 341.13000 ? 147 ILE A CG1   1 
ATOM   1206 C  CG2   . ILE A 1 147 ? 29.04000  42.59400  34.24000  1.000 331.19000 ? 147 ILE A CG2   1 
ATOM   1207 C  CD1   . ILE A 1 147 ? 26.24300  42.22000  34.02700  1.000 339.71000 ? 147 ILE A CD1   1 
ATOM   1208 N  N     . TYR A 1 148 ? 30.89000  42.88800  31.08900  1.000 315.67000 ? 148 TYR A N     1 
ATOM   1209 C  CA    . TYR A 1 148 ? 32.26300  42.53300  30.77300  1.000 317.85000 ? 148 TYR A CA    1 
ATOM   1210 C  C     . TYR A 1 148 ? 33.07800  43.77000  30.43700  1.000 320.21000 ? 148 TYR A C     1 
ATOM   1211 O  O     . TYR A 1 148 ? 34.25200  43.87200  30.80500  1.000 324.00000 ? 148 TYR A O     1 
ATOM   1212 C  CB    . TYR A 1 148 ? 32.26600  41.53200  29.62200  1.000 321.58000 ? 148 TYR A CB    1 
ATOM   1213 C  CG    . TYR A 1 148 ? 33.57200  41.43300  28.90200  1.000 330.24000 ? 148 TYR A CG    1 
ATOM   1214 C  CD1   . TYR A 1 148 ? 33.76400  42.04500  27.68000  1.000 332.92000 ? 148 TYR A CD1   1 
ATOM   1215 C  CD2   . TYR A 1 148 ? 34.61400  40.72900  29.44000  1.000 334.40000 ? 148 TYR A CD2   1 
ATOM   1216 C  CE1   . TYR A 1 148 ? 34.97000  41.94600  27.01900  1.000 336.22000 ? 148 TYR A CE1   1 
ATOM   1217 C  CE2   . TYR A 1 148 ? 35.83000  40.62000  28.79200  1.000 338.52000 ? 148 TYR A CE2   1 
ATOM   1218 C  CZ    . TYR A 1 148 ? 36.00000  41.22900  27.58200  1.000 340.73000 ? 148 TYR A CZ    1 
ATOM   1219 O  OH    . TYR A 1 148 ? 37.19400  41.13800  26.91300  1.000 343.64000 ? 148 TYR A OH    1 
ATOM   1220 N  N     . LYS A 1 149 ? 32.44100  44.75600  29.80800  1.000 324.05000 ? 149 LYS A N     1 
ATOM   1221 C  CA    . LYS A 1 149 ? 33.16500  45.93300  29.35800  1.000 326.74000 ? 149 LYS A CA    1 
ATOM   1222 C  C     . LYS A 1 149 ? 33.74500  46.71700  30.52400  1.000 330.38000 ? 149 LYS A C     1 
ATOM   1223 O  O     . LYS A 1 149 ? 34.90100  47.15000  30.48000  1.000 334.74000 ? 149 LYS A O     1 
ATOM   1224 C  CB    . LYS A 1 149 ? 32.24400  46.81900  28.52000  1.000 328.97000 ? 149 LYS A CB    1 
ATOM   1225 C  CG    . LYS A 1 149 ? 33.01600  47.66800  27.53100  1.000 337.77000 ? 149 LYS A CG    1 
ATOM   1226 C  CD    . LYS A 1 149 ? 34.15300  46.84700  26.89300  1.000 344.95000 ? 149 LYS A CD    1 
ATOM   1227 C  CE    . LYS A 1 149 ? 35.34100  47.71800  26.45900  1.000 353.66000 ? 149 LYS A CE    1 
ATOM   1228 N  NZ    . LYS A 1 149 ? 36.60200  46.94400  26.20100  1.000 358.91000 ? 149 LYS A NZ    1 
ATOM   1229 N  N     . TYR A 1 150 ? 32.97100  46.89800  31.58100  1.000 329.16000 ? 150 TYR A N     1 
ATOM   1230 C  CA    . TYR A 1 150 ? 33.30600  47.89300  32.59400  1.000 334.15000 ? 150 TYR A CA    1 
ATOM   1231 C  C     . TYR A 1 150 ? 33.70900  47.32400  33.93700  1.000 337.26000 ? 150 TYR A C     1 
ATOM   1232 O  O     . TYR A 1 150 ? 34.09500  48.08600  34.83200  1.000 347.27000 ? 150 TYR A O     1 
ATOM   1233 C  CB    . TYR A 1 150 ? 32.11700  48.83100  32.79900  1.000 341.02000 ? 150 TYR A CB    1 
ATOM   1234 C  CG    . TYR A 1 150 ? 31.95300  49.84000  31.69300  1.000 350.41000 ? 150 TYR A CG    1 
ATOM   1235 C  CD1   . TYR A 1 150 ? 30.91700  49.73200  30.77100  1.000 344.01000 ? 150 TYR A CD1   1 
ATOM   1236 C  CD2   . TYR A 1 150 ? 32.83200  50.90800  31.57600  1.000 359.69000 ? 150 TYR A CD2   1 
ATOM   1237 C  CE1   . TYR A 1 150 ? 30.76500  50.65500  29.77000  1.000 345.10000 ? 150 TYR A CE1   1 
ATOM   1238 C  CE2   . TYR A 1 150 ? 32.68700  51.83200  30.57400  1.000 366.58000 ? 150 TYR A CE2   1 
ATOM   1239 C  CZ    . TYR A 1 150 ? 31.65100  51.70600  29.67400  1.000 357.88000 ? 150 TYR A CZ    1 
ATOM   1240 O  OH    . TYR A 1 150 ? 31.50100  52.63500  28.66900  1.000 358.70000 ? 150 TYR A OH    1 
ATOM   1241 N  N     . CYS A 1 151 ? 33.61400  46.01600  34.11100  1.000 332.02000 ? 151 CYS A N     1 
ATOM   1242 C  CA    . CYS A 1 151 ? 33.71000  45.39900  35.42600  1.000 340.87000 ? 151 CYS A CA    1 
ATOM   1243 C  C     . CYS A 1 151 ? 35.08800  44.85000  35.71100  1.000 348.86000 ? 151 CYS A C     1 
ATOM   1244 O  O     . CYS A 1 151 ? 35.21000  43.83600  36.40700  1.000 349.42000 ? 151 CYS A O     1 
ATOM   1245 C  CB    . CYS A 1 151 ? 32.67500  44.28100  35.57300  1.000 338.91000 ? 151 CYS A CB    1 
ATOM   1246 S  SG    . CYS A 1 151 ? 31.00900  44.96600  35.58500  1.000 336.49000 ? 151 CYS A SG    1 
ATOM   1247 N  N     . ARG A 1 152 ? 36.11700  45.47900  35.17300  1.000 338.49000 ? 152 ARG A N     1 
ATOM   1248 C  CA    . ARG A 1 152 ? 37.46200  45.09000  35.49000  1.000 343.41000 ? 152 ARG A CA    1 
ATOM   1249 C  C     . ARG A 1 152 ? 38.25100  46.31400  35.96100  1.000 343.09000 ? 152 ARG A C     1 
ATOM   1250 O  O     . ARG A 1 152 ? 37.91200  47.45200  35.58800  1.000 343.64000 ? 152 ARG A O     1 
ATOM   1251 C  CB    . ARG A 1 152 ? 38.12800  44.40100  34.26100  1.000 350.61000 ? 152 ARG A CB    1 
ATOM   1252 C  CG    . ARG A 1 152 ? 37.30900  43.18000  33.62700  1.000 336.40000 ? 152 ARG A CG    1 
ATOM   1253 C  CD    . ARG A 1 152 ? 37.82000  42.52500  32.26100  1.000 332.49000 ? 152 ARG A CD    1 
ATOM   1254 N  NE    . ARG A 1 152 ? 38.45800  43.45300  31.33100  1.000 335.66000 ? 152 ARG A NE    1 
ATOM   1255 C  CZ    . ARG A 1 152 ? 37.80700  44.36700  30.62500  1.000 331.46000 ? 152 ARG A CZ    1 
ATOM   1256 N  NH1   . ARG A 1 152 ? 36.49700  44.47000  30.74000  1.000 320.17000 ? 152 ARG A NH1   1 
ATOM   1257 N  NH2   . ARG A 1 152 ? 38.46600  45.19200  29.82700  1.000 337.58000 ? 152 ARG A NH2   1 
ATOM   1258 N  N     . PRO A 1 153 ? 39.24700  46.12600  36.84700  1.000 339.75000 ? 153 PRO A N     1 
ATOM   1259 C  CA    . PRO A 1 153 ? 40.20500  47.21900  37.10800  1.000 339.75000 ? 153 PRO A CA    1 
ATOM   1260 C  C     . PRO A 1 153 ? 40.83400  47.69400  35.80300  1.000 351.27000 ? 153 PRO A C     1 
ATOM   1261 O  O     . PRO A 1 153 ? 40.95800  46.91700  34.85600  1.000 369.08000 ? 153 PRO A O     1 
ATOM   1262 C  CB    . PRO A 1 153 ? 41.26200  46.59200  38.02200  1.000 338.68000 ? 153 PRO A CB    1 
ATOM   1263 C  CG    . PRO A 1 153 ? 40.71900  45.23900  38.40900  1.000 327.00000 ? 153 PRO A CG    1 
ATOM   1264 C  CD    . PRO A 1 153 ? 39.62300  44.84000  37.48100  1.000 336.19000 ? 153 PRO A CD    1 
ATOM   1265 N  N     . ASN A 1 154 ? 41.17900  48.99400  35.72300  1.000 334.78000 ? 154 ASN A N     1 
ATOM   1266 C  CA    . ASN A 1 154 ? 41.87500  49.63000  34.56000  1.000 339.68000 ? 154 ASN A CA    1 
ATOM   1267 C  C     . ASN A 1 154 ? 40.91600  49.90300  33.38800  1.000 339.90000 ? 154 ASN A C     1 
ATOM   1268 O  O     . ASN A 1 154 ? 41.37000  50.40100  32.35100  1.000 342.88000 ? 154 ASN A O     1 
ATOM   1269 C  CB    . ASN A 1 154 ? 43.07100  48.78300  34.05900  1.000 345.18000 ? 154 ASN A CB    1 
ATOM   1270 C  CG    . ASN A 1 154 ? 43.98200  49.51000  33.06700  1.000 346.09000 ? 154 ASN A CG    1 
ATOM   1271 O  OD1   . ASN A 1 154 ? 44.67800  50.45500  33.41900  1.000 347.69000 ? 154 ASN A OD1   1 
ATOM   1272 N  ND2   . ASN A 1 154 ? 43.99300  49.04100  31.81800  1.000 343.63000 ? 154 ASN A ND2   1 
ATOM   1273 N  N     . SER A 1 155 ? 39.61300  49.65500  33.52700  1.000 341.90000 ? 155 SER A N     1 
ATOM   1274 C  CA    . SER A 1 155 ? 38.61700  50.04900  32.52800  1.000 345.41000 ? 155 SER A CA    1 
ATOM   1275 C  C     . SER A 1 155 ? 37.81200  51.21700  33.08400  1.000 348.60000 ? 155 SER A C     1 
ATOM   1276 O  O     . SER A 1 155 ? 37.14100  51.08500  34.11400  1.000 336.80000 ? 155 SER A O     1 
ATOM   1277 C  CB    . SER A 1 155 ? 37.69000  48.89400  32.14500  1.000 334.51000 ? 155 SER A CB    1 
ATOM   1278 O  OG    . SER A 1 155 ? 36.59400  48.81200  33.03400  1.000 327.42000 ? 155 SER A OG    1 
ATOM   1279 N  N     . VAL A 1 156 ? 37.87500  52.35000  32.39700  1.000 361.36000 ? 156 VAL A N     1 
ATOM   1280 C  CA    . VAL A 1 156 ? 37.45000  53.62900  32.94500  1.000 353.43000 ? 156 VAL A CA    1 
ATOM   1281 C  C     . VAL A 1 156 ? 36.13200  54.01200  32.29300  1.000 345.64000 ? 156 VAL A C     1 
ATOM   1282 O  O     . VAL A 1 156 ? 36.09500  54.47000  31.14900  1.000 347.10000 ? 156 VAL A O     1 
ATOM   1283 C  CB    . VAL A 1 156 ? 38.50800  54.71000  32.72900  1.000 346.58000 ? 156 VAL A CB    1 
ATOM   1284 C  CG1   . VAL A 1 156 ? 39.59500  54.58400  33.77500  1.000 349.75000 ? 156 VAL A CG1   1 
ATOM   1285 C  CG2   . VAL A 1 156 ? 39.12000  54.57000  31.33700  1.000 346.86000 ? 156 VAL A CG2   1 
ATOM   1286 N  N     . LEU A 1 157 ? 35.03900  53.82600  33.00200  1.000 360.56000 ? 157 LEU A N     1 
ATOM   1287 C  CA    . LEU A 1 157 ? 33.79200  54.36900  32.51400  1.000 365.36000 ? 157 LEU A CA    1 
ATOM   1288 C  C     . LEU A 1 157 ? 33.91500  55.88800  32.52200  1.000 375.02000 ? 157 LEU A C     1 
ATOM   1289 O  O     . LEU A 1 157 ? 34.46400  56.44600  33.48000  1.000 379.69000 ? 157 LEU A O     1 
ATOM   1290 C  CB    . LEU A 1 157 ? 32.64700  53.87000  33.38600  1.000 365.81000 ? 157 LEU A CB    1 
ATOM   1291 C  CG    . LEU A 1 157 ? 31.24200  54.43500  33.29700  1.000 369.06000 ? 157 LEU A CG    1 
ATOM   1292 C  CD1   . LEU A 1 157 ? 30.18900  53.29000  33.13900  1.000 366.65000 ? 157 LEU A CD1   1 
ATOM   1293 C  CD2   . LEU A 1 157 ? 31.01600  55.25500  34.52400  1.000 369.56000 ? 157 LEU A CD2   1 
ATOM   1294 N  N     . PRO A 1 158 ? 33.50600  56.57700  31.45000  1.000 384.58000 ? 158 PRO A N     1 
ATOM   1295 C  CA    . PRO A 1 158 ? 33.69800  58.03500  31.37700  1.000 389.10000 ? 158 PRO A CA    1 
ATOM   1296 C  C     . PRO A 1 158 ? 33.06000  58.74000  32.56700  1.000 409.80000 ? 158 PRO A C     1 
ATOM   1297 O  O     . PRO A 1 158 ? 32.11800  58.22100  33.17200  1.000 419.08000 ? 158 PRO A O     1 
ATOM   1298 C  CB    . PRO A 1 158 ? 32.99800  58.42300  30.06600  1.000 383.05000 ? 158 PRO A CB    1 
ATOM   1299 C  CG    . PRO A 1 158 ? 32.93400  57.18500  29.26700  1.000 371.97000 ? 158 PRO A CG    1 
ATOM   1300 C  CD    . PRO A 1 158 ? 32.93000  56.02200  30.21400  1.000 374.87000 ? 158 PRO A CD    1 
ATOM   1301 N  N     . ASN A 1 159 ? 33.56500  59.94900  32.88400  1.000 433.42000 ? 159 ASN A N     1 
ATOM   1302 C  CA    . ASN A 1 159 ? 33.02100  60.76400  33.97400  1.000 438.79000 ? 159 ASN A CA    1 
ATOM   1303 C  C     . ASN A 1 159 ? 31.63600  61.32000  33.60300  1.000 441.49000 ? 159 ASN A C     1 
ATOM   1304 O  O     . ASN A 1 159 ? 31.00500  62.01900  34.41000  1.000 443.62000 ? 159 ASN A O     1 
ATOM   1305 C  CB    . ASN A 1 159 ? 33.97800  61.92600  34.34900  1.000 426.82000 ? 159 ASN A CB    1 
ATOM   1306 C  CG    . ASN A 1 159 ? 35.36700  61.46000  34.87100  1.000 417.36000 ? 159 ASN A CG    1 
ATOM   1307 O  OD1   . ASN A 1 159 ? 35.52100  61.02100  36.02200  1.000 417.29000 ? 159 ASN A OD1   1 
ATOM   1308 N  ND2   . ASN A 1 159 ? 36.38600  61.63600  34.03400  1.000 406.48000 ? 159 ASN A ND2   1 
ATOM   1309 N  N     . GLU A 1 160 ? 31.14900  61.01200  32.38900  1.000 433.89000 ? 160 GLU A N     1 
ATOM   1310 C  CA    . GLU A 1 160 ? 29.86100  61.48300  31.87700  1.000 418.74000 ? 160 GLU A CA    1 
ATOM   1311 C  C     . GLU A 1 160 ? 28.81100  60.36900  31.78500  1.000 413.54000 ? 160 GLU A C     1 
ATOM   1312 O  O     . GLU A 1 160 ? 27.81200  60.52200  31.08000  1.000 415.14000 ? 160 GLU A O     1 
ATOM   1313 C  CB    . GLU A 1 160 ? 30.06400  62.15600  30.51500  1.000 405.79000 ? 160 GLU A CB    1 
ATOM   1314 C  CG    . GLU A 1 160 ? 31.24300  63.15700  30.46500  1.000 409.48000 ? 160 GLU A CG    1 
ATOM   1315 C  CD    . GLU A 1 160 ? 32.59900  62.49100  30.19900  1.000 413.03000 ? 160 GLU A CD    1 
ATOM   1316 O  OE1   . GLU A 1 160 ? 33.37300  62.97600  29.34400  1.000 409.82000 ? 160 GLU A OE1   1 
ATOM   1317 O  OE2   . GLU A 1 160 ? 32.89100  61.46500  30.84300  1.000 418.48000 ? 160 GLU A OE2   1 
ATOM   1318 N  N     . LEU A 1 161 ? 29.02600  59.25300  32.49000  1.000 409.08000 ? 161 LEU A N     1 
ATOM   1319 C  CA    . LEU A 1 161 ? 28.01400  58.23300  32.75200  1.000 401.56000 ? 161 LEU A CA    1 
ATOM   1320 C  C     . LEU A 1 161 ? 27.76500  57.93800  34.24800  1.000 400.57000 ? 161 LEU A C     1 
ATOM   1321 O  O     . LEU A 1 161 ? 26.80100  57.22800  34.54900  1.000 395.57000 ? 161 LEU A O     1 
ATOM   1322 C  CB    . LEU A 1 161 ? 28.38200  56.90300  32.04800  1.000 383.35000 ? 161 LEU A CB    1 
ATOM   1323 C  CG    . LEU A 1 161 ? 28.85800  56.85400  30.58800  1.000 374.92000 ? 161 LEU A CG    1 
ATOM   1324 C  CD1   . LEU A 1 161 ? 29.42700  55.47900  30.26200  1.000 362.58000 ? 161 LEU A CD1   1 
ATOM   1325 C  CD2   . LEU A 1 161 ? 27.73700  57.19800  29.63100  1.000 365.71000 ? 161 LEU A CD2   1 
ATOM   1326 N  N     . VAL A 1 162 ? 28.57000  58.46000  35.18000  1.000 415.63000 ? 162 VAL A N     1 
ATOM   1327 C  CA    . VAL A 1 162 ? 28.48700  58.09600  36.60000  1.000 397.65000 ? 162 VAL A CA    1 
ATOM   1328 C  C     . VAL A 1 162 ? 27.32200  58.85700  37.23400  1.000 404.64000 ? 162 VAL A C     1 
ATOM   1329 O  O     . VAL A 1 162 ? 27.31700  60.09300  37.23000  1.000 407.96000 ? 162 VAL A O     1 
ATOM   1330 C  CB    . VAL A 1 162 ? 29.79400  58.41200  37.34500  1.000 388.57000 ? 162 VAL A CB    1 
ATOM   1331 C  CG1   . VAL A 1 162 ? 29.55700  58.24700  38.82200  1.000 381.35000 ? 162 VAL A CG1   1 
ATOM   1332 C  CG2   . VAL A 1 162 ? 30.95900  57.59300  36.85900  1.000 381.04000 ? 162 VAL A CG2   1 
ATOM   1333 N  N     . GLN A 1 163 ? 26.40400  58.14100  37.89600  1.000 404.84000 ? 163 GLN A N     1 
ATOM   1334 C  CA    . GLN A 1 163 ? 25.33200  58.85700  38.57400  1.000 412.27000 ? 163 GLN A CA    1 
ATOM   1335 C  C     . GLN A 1 163 ? 25.73200  59.27500  39.98800  1.000 417.38000 ? 163 GLN A C     1 
ATOM   1336 O  O     . GLN A 1 163 ? 25.32200  60.34300  40.44300  1.000 423.27000 ? 163 GLN A O     1 
ATOM   1337 C  CB    . GLN A 1 163 ? 24.05200  58.01300  38.54100  1.000 406.87000 ? 163 GLN A CB    1 
ATOM   1338 C  CG    . GLN A 1 163 ? 23.58300  57.62600  37.12500  1.000 395.40000 ? 163 GLN A CG    1 
ATOM   1339 C  CD    . GLN A 1 163 ? 23.14800  58.80800  36.25700  1.000 391.12000 ? 163 GLN A CD    1 
ATOM   1340 O  OE1   . GLN A 1 163 ? 21.96500  58.96200  35.95300  1.000 384.03000 ? 163 GLN A OE1   1 
ATOM   1341 N  NE2   . GLN A 1 163 ? 24.10200  59.64300  35.85400  1.000 393.71000 ? 163 GLN A NE2   1 
ATOM   1342 N  N     . THR A 1 164 ? 26.53700  58.48100  40.69700  1.000 412.51000 ? 164 THR A N     1 
ATOM   1343 C  CA    . THR A 1 164 ? 26.98500  58.84800  42.04000  1.000 403.41000 ? 164 THR A CA    1 
ATOM   1344 C  C     . THR A 1 164 ? 28.50200  58.98000  42.07900  1.000 401.30000 ? 164 THR A C     1 
ATOM   1345 O  O     . THR A 1 164 ? 29.21600  58.06700  41.65400  1.000 401.63000 ? 164 THR A O     1 
ATOM   1346 C  CB    . THR A 1 164 ? 26.52000  57.81400  43.07300  1.000 395.01000 ? 164 THR A CB    1 
ATOM   1347 O  OG1   . THR A 1 164 ? 25.89200  56.72100  42.39000  1.000 399.27000 ? 164 THR A OG1   1 
ATOM   1348 C  CG2   . THR A 1 164 ? 25.50700  58.43400  44.02400  1.000 389.05000 ? 164 THR A CG2   1 
ATOM   1349 N  N     . LYS A 1 165 ? 28.99100  60.11800  42.57000  1.000 410.99000 ? 165 LYS A N     1 
ATOM   1350 C  CA    . LYS A 1 165 ? 30.42300  60.26700  42.79900  1.000 398.65000 ? 165 LYS A CA    1 
ATOM   1351 C  C     . LYS A 1 165 ? 30.85900  59.25100  43.85200  1.000 404.78000 ? 165 LYS A C     1 
ATOM   1352 O  O     . LYS A 1 165 ? 30.09500  58.93700  44.77600  1.000 402.24000 ? 165 LYS A O     1 
ATOM   1353 C  CB    . LYS A 1 165 ? 30.75700  61.70300  43.23800  1.000 393.34000 ? 165 LYS A CB    1 
ATOM   1354 C  CG    . LYS A 1 165 ? 30.77300  62.78700  42.11800  1.000 381.26000 ? 165 LYS A CG    1 
ATOM   1355 C  CD    . LYS A 1 165 ? 29.61400  62.68000  41.10000  1.000 377.83000 ? 165 LYS A CD    1 
ATOM   1356 C  CE    . LYS A 1 165 ? 28.80400  63.97300  40.94700  1.000 374.12000 ? 165 LYS A CE    1 
ATOM   1357 N  NZ    . LYS A 1 165 ? 27.42900  63.68300  40.44000  1.000 370.64000 ? 165 LYS A NZ    1 
ATOM   1358 N  N     . SER A 1 166 ? 32.07500  58.70600  43.68200  1.000 427.40000 ? 166 SER A N     1 
ATOM   1359 C  CA    . SER A 1 166 ? 32.56000  57.62900  44.55200  1.000 423.47000 ? 166 SER A CA    1 
ATOM   1360 C  C     . SER A 1 166 ? 32.46600  58.02100  46.02600  1.000 412.95000 ? 166 SER A C     1 
ATOM   1361 O  O     . SER A 1 166 ? 32.83600  59.13900  46.41400  1.000 413.01000 ? 166 SER A O     1 
ATOM   1362 C  CB    . SER A 1 166 ? 34.01100  57.25200  44.19400  1.000 416.84000 ? 166 SER A CB    1 
ATOM   1363 O  OG    . SER A 1 166 ? 34.44200  56.09500  44.90900  1.000 411.74000 ? 166 SER A OG    1 
ATOM   1364 N  N     . LEU A 1 167 ? 31.98900  57.07500  46.85100  1.000 409.44000 ? 167 LEU A N     1 
ATOM   1365 C  CA    . LEU A 1 167 ? 31.81800  57.35700  48.27100  1.000 402.58000 ? 167 LEU A CA    1 
ATOM   1366 C  C     . LEU A 1 167 ? 33.15800  57.66800  48.94500  1.000 407.10000 ? 167 LEU A C     1 
ATOM   1367 O  O     . LEU A 1 167 ? 33.22000  58.51900  49.84300  1.000 409.00000 ? 167 LEU A O     1 
ATOM   1368 C  CB    . LEU A 1 167 ? 31.10400  56.17500  48.93700  1.000 392.32000 ? 167 LEU A CB    1 
ATOM   1369 C  CG    . LEU A 1 167 ? 29.80400  55.68200  48.26800  1.000 380.91000 ? 167 LEU A CG    1 
ATOM   1370 C  CD1   . LEU A 1 167 ? 29.01800  54.83400  49.24800  1.000 373.62000 ? 167 LEU A CD1   1 
ATOM   1371 C  CD2   . LEU A 1 167 ? 28.93400  56.81400  47.71900  1.000 383.33000 ? 167 LEU A CD2   1 
ATOM   1372 N  N     . ILE A 1 168 ? 34.23700  56.98400  48.53000  1.000 415.79000 ? 168 ILE A N     1 
ATOM   1373 C  CA    . ILE A 1 168 ? 35.61700  57.34900  48.88600  1.000 412.25000 ? 168 ILE A CA    1 
ATOM   1374 C  C     . ILE A 1 168 ? 36.55300  56.91900  47.74900  1.000 412.84000 ? 168 ILE A C     1 
ATOM   1375 O  O     . ILE A 1 168 ? 36.25500  55.98500  47.00000  1.000 417.92000 ? 168 ILE A O     1 
ATOM   1376 C  CB    . ILE A 1 168 ? 36.05200  56.73700  50.25900  1.000 400.91000 ? 168 ILE A CB    1 
ATOM   1377 C  CG1   . ILE A 1 168 ? 37.36300  57.35400  50.79400  1.000 383.92000 ? 168 ILE A CG1   1 
ATOM   1378 C  CG2   . ILE A 1 168 ? 36.18400  55.21900  50.18500  1.000 407.20000 ? 168 ILE A CG2   1 
ATOM   1379 C  CD1   . ILE A 1 168 ? 37.95000  56.67100  52.05800  1.000 353.81000 ? 168 ILE A CD1   1 
ATOM   1380 N  N     . SER A 1 169 ? 37.68300  57.62300  47.60900  1.000 414.09000 ? 169 SER A N     1 
ATOM   1381 C  CA    . SER A 1 169 ? 38.70300  57.30300  46.59600  1.000 401.93000 ? 169 SER A CA    1 
ATOM   1382 C  C     . SER A 1 169 ? 39.57700  56.12000  47.02700  1.000 393.77000 ? 169 SER A C     1 
ATOM   1383 O  O     . SER A 1 169 ? 39.46800  55.61300  48.15100  1.000 399.90000 ? 169 SER A O     1 
ATOM   1384 C  CB    . SER A 1 169 ? 39.59700  58.51700  46.30500  1.000 392.56000 ? 169 SER A CB    1 
ATOM   1385 O  OG    . SER A 1 169 ? 38.89700  59.55500  45.64000  1.000 400.40000 ? 169 SER A OG    1 
ATOM   1386 N  N     . ASP A 1 203 ? 39.18200  40.24300  43.82000  1.000 335.72000 ? 203 ASP A N     1 
ATOM   1387 C  CA    . ASP A 1 203 ? 39.52300  41.64400  43.63300  1.000 336.77000 ? 203 ASP A CA    1 
ATOM   1388 C  C     . ASP A 1 203 ? 38.39900  42.39300  42.92000  1.000 335.75000 ? 203 ASP A C     1 
ATOM   1389 O  O     . ASP A 1 203 ? 37.33100  42.61800  43.48800  1.000 331.63000 ? 203 ASP A O     1 
ATOM   1390 C  CB    . ASP A 1 203 ? 40.83000  41.78500  42.83900  1.000 339.11000 ? 203 ASP A CB    1 
ATOM   1391 C  CG    . ASP A 1 203 ? 41.29200  43.22600  42.74100  1.000 333.81000 ? 203 ASP A CG    1 
ATOM   1392 O  OD1   . ASP A 1 203 ? 41.23900  43.92000  43.77400  1.000 347.03000 ? 203 ASP A OD1   1 
ATOM   1393 O  OD2   . ASP A 1 203 ? 41.67500  43.67300  41.64100  1.000 326.37000 ? 203 ASP A OD2   1 
ATOM   1394 N  N     . ALA A 1 204 ? 38.65400  42.78100  41.67200  1.000 330.37000 ? 204 ALA A N     1 
ATOM   1395 C  CA    . ALA A 1 204 ? 37.71200  43.56800  40.89600  1.000 328.18000 ? 204 ALA A CA    1 
ATOM   1396 C  C     . ALA A 1 204 ? 37.42000  42.93300  39.54200  1.000 332.89000 ? 204 ALA A C     1 
ATOM   1397 O  O     . ALA A 1 204 ? 36.84700  43.57800  38.66400  1.000 333.13000 ? 204 ALA A O     1 
ATOM   1398 C  CB    . ALA A 1 204 ? 38.23400  44.98900  40.72700  1.000 330.10000 ? 204 ALA A CB    1 
ATOM   1399 N  N     . GLN A 1 205 ? 37.79200  41.68200  39.34900  1.000 322.70000 ? 205 GLN A N     1 
ATOM   1400 C  CA    . GLN A 1 205 ? 37.36400  40.93000  38.18200  1.000 311.73000 ? 205 GLN A CA    1 
ATOM   1401 C  C     . GLN A 1 205 ? 36.03400  40.25500  38.48600  1.000 309.97000 ? 205 GLN A C     1 
ATOM   1402 O  O     . GLN A 1 205 ? 35.94400  39.44000  39.40700  1.000 311.49000 ? 205 GLN A O     1 
ATOM   1403 C  CB    . GLN A 1 205 ? 38.40700  39.90400  37.78700  1.000 312.85000 ? 205 GLN A CB    1 
ATOM   1404 C  CG    . GLN A 1 205 ? 38.55300  39.81700  36.32100  1.000 322.84000 ? 205 GLN A CG    1 
ATOM   1405 C  CD    . GLN A 1 205 ? 39.97900  39.67700  35.95400  1.000 341.23000 ? 205 GLN A CD    1 
ATOM   1406 O  OE1   . GLN A 1 205 ? 40.71800  40.65300  35.91500  1.000 341.32000 ? 205 GLN A OE1   1 
ATOM   1407 N  NE2   . GLN A 1 205 ? 40.39700  38.45300  35.70500  1.000 348.01000 ? 205 GLN A NE2   1 
ATOM   1408 N  N     . PHE A 1 206 ? 35.01400  40.57300  37.68500  1.000 315.30000 ? 206 PHE A N     1 
ATOM   1409 C  CA    . PHE A 1 206 ? 33.63000  40.33800  38.08300  1.000 308.39000 ? 206 PHE A CA    1 
ATOM   1410 C  C     . PHE A 1 206 ? 33.32000  38.85000  38.13200  1.000 306.48000 ? 206 PHE A C     1 
ATOM   1411 O  O     . PHE A 1 206 ? 32.63400  38.35700  39.04200  1.000 307.78000 ? 206 PHE A O     1 
ATOM   1412 C  CB    . PHE A 1 206 ? 32.71200  41.01900  37.09600  1.000 309.82000 ? 206 PHE A CB    1 
ATOM   1413 C  CG    . PHE A 1 206 ? 31.34400  40.42500  37.05500  1.000 307.39000 ? 206 PHE A CG    1 
ATOM   1414 C  CD1   . PHE A 1 206 ? 31.07800  39.29500  36.30700  1.000 307.05000 ? 206 PHE A CD1   1 
ATOM   1415 C  CD2   . PHE A 1 206 ? 30.31700  41.01300  37.73700  1.000 307.75000 ? 206 PHE A CD2   1 
ATOM   1416 C  CE1   . PHE A 1 206 ? 29.84300  38.74000  36.28800  1.000 304.68000 ? 206 PHE A CE1   1 
ATOM   1417 C  CE2   . PHE A 1 206 ? 29.06800  40.47300  37.71400  1.000 307.12000 ? 206 PHE A CE2   1 
ATOM   1418 C  CZ    . PHE A 1 206 ? 28.82000  39.33300  36.98200  1.000 305.86000 ? 206 PHE A CZ    1 
ATOM   1419 N  N     . HIS A 1 207 ? 33.74900  38.13500  37.09300  1.000 311.96000 ? 207 HIS A N     1 
ATOM   1420 C  CA    . HIS A 1 207 ? 33.41000  36.73400  36.97000  1.000 313.96000 ? 207 HIS A CA    1 
ATOM   1421 C  C     . HIS A 1 207 ? 34.12400  35.91900  38.05300  1.000 320.61000 ? 207 HIS A C     1 
ATOM   1422 O  O     . HIS A 1 207 ? 33.47700  35.14500  38.77700  1.000 320.54000 ? 207 HIS A O     1 
ATOM   1423 C  CB    . HIS A 1 207 ? 33.76500  36.26800  35.54300  1.000 313.27000 ? 207 HIS A CB    1 
ATOM   1424 C  CG    . HIS A 1 207 ? 35.22100  36.34700  35.19000  1.000 317.52000 ? 207 HIS A CG    1 
ATOM   1425 N  ND1   . HIS A 1 207 ? 35.76600  37.32200  34.39500  1.000 313.58000 ? 207 HIS A ND1   1 
ATOM   1426 C  CD2   . HIS A 1 207 ? 36.23700  35.52600  35.50400  1.000 320.28000 ? 207 HIS A CD2   1 
ATOM   1427 C  CE1   . HIS A 1 207 ? 37.06100  37.10800  34.25200  1.000 316.57000 ? 207 HIS A CE1   1 
ATOM   1428 N  NE2   . HIS A 1 207 ? 37.37100  36.02300  34.92200  1.000 318.16000 ? 207 HIS A NE2   1 
ATOM   1429 N  N     . ASP A 1 208 ? 35.45900  36.10200  38.21100  1.000 329.76000 ? 208 ASP A N     1 
ATOM   1430 C  CA    . ASP A 1 208 ? 36.18900  35.31200  39.21000  1.000 323.92000 ? 208 ASP A CA    1 
ATOM   1431 C  C     . ASP A 1 208 ? 35.59900  35.53800  40.58700  1.000 318.03000 ? 208 ASP A C     1 
ATOM   1432 O  O     . ASP A 1 208 ? 35.48200  34.60100  41.39100  1.000 316.00000 ? 208 ASP A O     1 
ATOM   1433 C  CB    . ASP A 1 208 ? 37.68600  35.67600  39.24300  1.000 322.85000 ? 208 ASP A CB    1 
ATOM   1434 C  CG    . ASP A 1 208 ? 38.32600  35.77600  37.86100  1.000 320.35000 ? 208 ASP A CG    1 
ATOM   1435 O  OD1   . ASP A 1 208 ? 38.43200  36.90000  37.32900  1.000 326.78000 ? 208 ASP A OD1   1 
ATOM   1436 O  OD2   . ASP A 1 208 ? 38.78300  34.74300  37.33500  1.000 323.64000 ? 208 ASP A OD2   1 
ATOM   1437 N  N     . GLN A 1 209 ? 35.27000  36.80500  40.87700  1.000 322.80000 ? 209 GLN A N     1 
ATOM   1438 C  CA    . GLN A 1 209 ? 34.54300  37.15900  42.08900  1.000 320.58000 ? 209 GLN A CA    1 
ATOM   1439 C  C     . GLN A 1 209 ? 33.20000  36.45000  42.14700  1.000 315.82000 ? 209 GLN A C     1 
ATOM   1440 O  O     . GLN A 1 209 ? 32.82200  35.90300  43.19200  1.000 315.65000 ? 209 GLN A O     1 
ATOM   1441 C  CB    . GLN A 1 209 ? 34.33400  38.67900  42.14600  1.000 319.51000 ? 209 GLN A CB    1 
ATOM   1442 C  CG    . GLN A 1 209 ? 35.10400  39.41000  43.25400  1.000 327.77000 ? 209 GLN A CG    1 
ATOM   1443 C  CD    . GLN A 1 209 ? 34.36900  40.64300  43.80200  1.000 327.77000 ? 209 GLN A CD    1 
ATOM   1444 O  OE1   . GLN A 1 209 ? 33.66600  40.56200  44.81500  1.000 334.10000 ? 209 GLN A OE1   1 
ATOM   1445 N  NE2   . GLN A 1 209 ? 34.53700  41.78500  43.13900  1.000 331.32000 ? 209 GLN A NE2   1 
ATOM   1446 N  N     . LEU A 1 210 ? 32.46700  36.43600  41.02800  1.000 315.98000 ? 210 LEU A N     1 
ATOM   1447 C  CA    . LEU A 1 210 ? 31.19800  35.72300  41.02600  1.000 313.27000 ? 210 LEU A CA    1 
ATOM   1448 C  C     . LEU A 1 210 ? 31.38800  34.29400  41.50200  1.000 312.62000 ? 210 LEU A C     1 
ATOM   1449 O  O     . LEU A 1 210 ? 30.62800  33.81300  42.35800  1.000 314.73000 ? 210 LEU A O     1 
ATOM   1450 C  CB    . LEU A 1 210 ? 30.58000  35.74400  39.63500  1.000 311.83000 ? 210 LEU A CB    1 
ATOM   1451 C  CG    . LEU A 1 210 ? 29.06200  35.78400  39.50300  1.000 311.56000 ? 210 LEU A CG    1 
ATOM   1452 C  CD1   . LEU A 1 210 ? 28.71400  36.12400  38.04600  1.000 317.61000 ? 210 LEU A CD1   1 
ATOM   1453 C  CD2   . LEU A 1 210 ? 28.42400  34.48400  39.97100  1.000 308.47000 ? 210 LEU A CD2   1 
ATOM   1454 N  N     . LYS A 1 211 ? 32.42900  33.61900  40.99400  1.000 318.03000 ? 211 LYS A N     1 
ATOM   1455 C  CA    . LYS A 1 211 ? 32.70700  32.25800  41.44100  1.000 318.96000 ? 211 LYS A CA    1 
ATOM   1456 C  C     . LYS A 1 211 ? 33.11800  32.24600  42.89800  1.000 319.60000 ? 211 LYS A C     1 
ATOM   1457 O  O     . LYS A 1 211 ? 32.74700  31.34000  43.65500  1.000 317.15000 ? 211 LYS A O     1 
ATOM   1458 C  CB    . LYS A 1 211 ? 33.81100  31.62400  40.59000  1.000 322.35000 ? 211 LYS A CB    1 
ATOM   1459 C  CG    . LYS A 1 211 ? 33.37400  31.08000  39.23000  1.000 330.87000 ? 211 LYS A CG    1 
ATOM   1460 C  CD    . LYS A 1 211 ? 34.26900  31.54300  38.08000  1.000 334.89000 ? 211 LYS A CD    1 
ATOM   1461 C  CE    . LYS A 1 211 ? 33.63400  31.04800  36.75100  1.000 332.06000 ? 211 LYS A CE    1 
ATOM   1462 N  NZ    . LYS A 1 211 ? 34.54800  31.26300  35.58300  1.000 327.51000 ? 211 LYS A NZ    1 
ATOM   1463 N  N     . ALA A 1 212 ? 33.88400  33.24900  43.31000  1.000 324.97000 ? 212 ALA A N     1 
ATOM   1464 C  CA    . ALA A 1 212 ? 34.45100  33.22100  44.64800  1.000 329.84000 ? 212 ALA A CA    1 
ATOM   1465 C  C     . ALA A 1 212 ? 33.39000  33.46000  45.70800  1.000 329.18000 ? 212 ALA A C     1 
ATOM   1466 O  O     . ALA A 1 212 ? 33.43900  32.85700  46.78600  1.000 327.18000 ? 212 ALA A O     1 
ATOM   1467 C  CB    . ALA A 1 212 ? 35.56900  34.24400  44.77000  1.000 332.18000 ? 212 ALA A CB    1 
ATOM   1468 N  N     . ARG A 1 213 ? 32.41700  34.33500  45.42700  1.000 330.02000 ? 213 ARG A N     1 
ATOM   1469 C  CA    . ARG A 1 213 ? 31.39800  34.60100  46.43900  1.000 330.77000 ? 213 ARG A CA    1 
ATOM   1470 C  C     . ARG A 1 213 ? 30.40900  33.44700  46.51200  1.000 322.71000 ? 213 ARG A C     1 
ATOM   1471 O  O     . ARG A 1 213 ? 30.04900  32.99500  47.60800  1.000 325.66000 ? 213 ARG A O     1 
ATOM   1472 C  CB    . ARG A 1 213 ? 30.68700  35.94300  46.17100  1.000 332.57000 ? 213 ARG A CB    1 
ATOM   1473 C  CG    . ARG A 1 213 ? 29.62800  36.37000  47.26400  1.000 333.93000 ? 213 ARG A CG    1 
ATOM   1474 C  CD    . ARG A 1 213 ? 29.86100  37.72800  47.94100  1.000 331.24000 ? 213 ARG A CD    1 
ATOM   1475 N  NE    . ARG A 1 213 ? 29.63000  38.83300  47.02100  1.000 328.11000 ? 213 ARG A NE    1 
ATOM   1476 C  CZ    . ARG A 1 213 ? 30.59900  39.50600  46.40800  1.000 328.92000 ? 213 ARG A CZ    1 
ATOM   1477 N  NH1   . ARG A 1 213 ? 31.86400  39.20500  46.63400  1.000 333.68000 ? 213 ARG A NH1   1 
ATOM   1478 N  NH2   . ARG A 1 213 ? 30.31000  40.48900  45.57900  1.000 334.67000 ? 213 ARG A NH2   1 
ATOM   1479 N  N     . LEU A 1 214 ? 30.01500  32.91000  45.36000  1.000 322.11000 ? 214 LEU A N     1 
ATOM   1480 C  CA    . LEU A 1 214 ? 29.30300  31.64700  45.36400  1.000 322.94000 ? 214 LEU A CA    1 
ATOM   1481 C  C     . LEU A 1 214 ? 30.13100  30.48700  45.87900  1.000 319.84000 ? 214 LEU A C     1 
ATOM   1482 O  O     . LEU A 1 214 ? 29.64700  29.35700  45.85200  1.000 324.58000 ? 214 LEU A O     1 
ATOM   1483 C  CB    . LEU A 1 214 ? 28.82700  31.33400  43.95700  1.000 328.33000 ? 214 LEU A CB    1 
ATOM   1484 C  CG    . LEU A 1 214 ? 27.41900  31.77500  43.58900  1.000 331.65000 ? 214 LEU A CG    1 
ATOM   1485 C  CD1   . LEU A 1 214 ? 27.30400  32.11300  42.10600  1.000 321.96000 ? 214 LEU A CD1   1 
ATOM   1486 C  CD2   . LEU A 1 214 ? 26.44100  30.67700  43.98700  1.000 330.78000 ? 214 LEU A CD2   1 
ATOM   1487 N  N     . LEU A 1 215 ? 31.35400  30.70600  46.36000  1.000 314.95000 ? 215 LEU A N     1 
ATOM   1488 C  CA    . LEU A 1 215 ? 32.22300  29.57800  46.70300  1.000 317.28000 ? 215 LEU A CA    1 
ATOM   1489 C  C     . LEU A 1 215 ? 31.76200  28.84300  47.95800  1.000 318.56000 ? 215 LEU A C     1 
ATOM   1490 O  O     . LEU A 1 215 ? 31.84000  27.60800  48.02200  1.000 316.67000 ? 215 LEU A O     1 
ATOM   1491 C  CB    . LEU A 1 215 ? 33.65400  30.05200  46.87300  1.000 315.03000 ? 215 LEU A CB    1 
ATOM   1492 C  CG    . LEU A 1 215 ? 34.76600  29.20700  46.27500  1.000 321.03000 ? 215 LEU A CG    1 
ATOM   1493 C  CD1   . LEU A 1 215 ? 35.21300  28.12000  47.23400  1.000 319.91000 ? 215 LEU A CD1   1 
ATOM   1494 C  CD2   . LEU A 1 215 ? 34.30500  28.60500  44.94200  1.000 325.14000 ? 215 LEU A CD2   1 
ATOM   1495 N  N     . GLU A 1 216 ? 31.27400  29.57900  48.96300  1.000 321.02000 ? 216 GLU A N     1 
ATOM   1496 C  CA    . GLU A 1 216 ? 30.98000  28.96600  50.25800  1.000 326.87000 ? 216 GLU A CA    1 
ATOM   1497 C  C     . GLU A 1 216 ? 29.84100  27.95400  50.14700  1.000 326.26000 ? 216 GLU A C     1 
ATOM   1498 O  O     . GLU A 1 216 ? 29.91900  26.85900  50.72400  1.000 318.61000 ? 216 GLU A O     1 
ATOM   1499 C  CB    . GLU A 1 216 ? 30.66500  30.06700  51.28900  1.000 335.77000 ? 216 GLU A CB    1 
ATOM   1500 C  CG    . GLU A 1 216 ? 29.32500  30.81100  51.08600  1.000 341.88000 ? 216 GLU A CG    1 
ATOM   1501 C  CD    . GLU A 1 216 ? 29.27000  32.19700  51.72000  1.000 342.98000 ? 216 GLU A CD    1 
ATOM   1502 O  OE1   . GLU A 1 216 ? 29.41400  33.19800  50.97800  1.000 345.72000 ? 216 GLU A OE1   1 
ATOM   1503 O  OE2   . GLU A 1 216 ? 29.05600  32.27500  52.94700  1.000 343.38000 ? 216 GLU A OE2   1 
ATOM   1504 N  N     . HIS A 1 217 ? 28.79600  28.29400  49.36900  1.000 329.20000 ? 217 HIS A N     1 
ATOM   1505 C  CA    . HIS A 1 217 ? 27.68600  27.40200  49.02700  1.000 327.55000 ? 217 HIS A CA    1 
ATOM   1506 C  C     . HIS A 1 217 ? 27.86300  26.87200  47.60500  1.000 320.71000 ? 217 HIS A C     1 
ATOM   1507 O  O     . HIS A 1 217 ? 27.69900  27.61700  46.63700  1.000 319.31000 ? 217 HIS A O     1 
ATOM   1508 C  CB    . HIS A 1 217 ? 26.33200  28.10400  49.14700  1.000 327.06000 ? 217 HIS A CB    1 
ATOM   1509 C  CG    . HIS A 1 217 ? 26.40200  29.59900  49.07400  1.000 325.14000 ? 217 HIS A CG    1 
ATOM   1510 N  ND1   . HIS A 1 217 ? 25.74400  30.40100  49.98000  1.000 326.54000 ? 217 HIS A ND1   1 
ATOM   1511 C  CD2   . HIS A 1 217 ? 27.01400  30.44000  48.20300  1.000 324.28000 ? 217 HIS A CD2   1 
ATOM   1512 C  CE1   . HIS A 1 217 ? 25.95800  31.67000  49.68300  1.000 328.16000 ? 217 HIS A CE1   1 
ATOM   1513 N  NE2   . HIS A 1 217 ? 26.73000  31.72300  48.61200  1.000 323.98000 ? 217 HIS A NE2   1 
ATOM   1514 N  N     . THR A 1 218 ? 28.12600  25.57100  47.49000  1.000 313.56000 ? 218 THR A N     1 
ATOM   1515 C  CA    . THR A 1 218 ? 28.63600  24.95200  46.27000  1.000 312.63000 ? 218 THR A CA    1 
ATOM   1516 C  C     . THR A 1 218 ? 27.56200  24.93200  45.19000  1.000 309.38000 ? 218 THR A C     1 
ATOM   1517 O  O     . THR A 1 218 ? 26.49400  24.31200  45.35600  1.000 298.87000 ? 218 THR A O     1 
ATOM   1518 C  CB    . THR A 1 218 ? 29.15700  23.54900  46.58500  1.000 306.81000 ? 218 THR A CB    1 
ATOM   1519 O  OG1   . THR A 1 218 ? 28.07300  22.62000  46.75800  1.000 303.87000 ? 218 THR A OG1   1 
ATOM   1520 C  CG2   . THR A 1 218 ? 30.01900  23.58000  47.87000  1.000 303.96000 ? 218 THR A CG2   1 
ATOM   1521 N  N     . ILE A 1 219 ? 27.83600  25.69500  44.12400  1.000 309.08000 ? 219 ILE A N     1 
ATOM   1522 C  CA    . ILE A 1 219 ? 26.96900  25.81600  42.94400  1.000 299.11000 ? 219 ILE A CA    1 
ATOM   1523 C  C     . ILE A 1 219 ? 27.77500  25.95200  41.72400  1.000 294.28000 ? 219 ILE A C     1 
ATOM   1524 O  O     . ILE A 1 219 ? 28.77600  26.77900  41.64200  1.000 296.73000 ? 219 ILE A O     1 
ATOM   1525 C  CB    . ILE A 1 219 ? 25.96400  26.99300  43.06600  1.000 301.24000 ? 219 ILE A CB    1 
ATOM   1526 C  CG1   . ILE A 1 219 ? 24.96300  26.73400  44.18600  1.000 306.48000 ? 219 ILE A CG1   1 
ATOM   1527 C  CG2   . ILE A 1 219 ? 25.26600  27.23000  41.72400  1.000 301.15000 ? 219 ILE A CG2   1 
ATOM   1528 C  CD1   . ILE A 1 219 ? 24.54700  27.95800  44.97800  1.000 304.28000 ? 219 ILE A CD1   1 
ATOM   1529 N  N     . PRO A 1 220 ? 27.55800  25.19200  40.70000  1.000 292.29000 ? 220 PRO A N     1 
ATOM   1530 C  CA    . PRO A 1 220 ? 28.31000  25.28100  39.47000  1.000 294.69000 ? 220 PRO A CA    1 
ATOM   1531 C  C     . PRO A 1 220 ? 27.96900  26.52200  38.67800  1.000 296.50000 ? 220 PRO A C     1 
ATOM   1532 O  O     . PRO A 1 220 ? 26.82100  26.71600  38.28200  1.000 297.97000 ? 220 PRO A O     1 
ATOM   1533 C  CB    . PRO A 1 220 ? 27.92400  24.01900  38.69500  1.000 294.77000 ? 220 PRO A CB    1 
ATOM   1534 C  CG    . PRO A 1 220 ? 26.94700  23.29000  39.58600  1.000 292.14000 ? 220 PRO A CG    1 
ATOM   1535 C  CD    . PRO A 1 220 ? 26.45100  24.22500  40.60100  1.000 295.18000 ? 220 PRO A CD    1 
ATOM   1536 N  N     . THR A 1 221 ? 28.96500  27.35000  38.43200  1.000 305.62000 ? 221 THR A N     1 
ATOM   1537 C  CA    . THR A 1 221 ? 28.80000  28.61800  37.73900  1.000 310.25000 ? 221 THR A CA    1 
ATOM   1538 C  C     . THR A 1 221 ? 29.51400  28.53300  36.40300  1.000 300.87000 ? 221 THR A C     1 
ATOM   1539 O  O     . THR A 1 221 ? 30.73800  28.40600  36.35600  1.000 301.62000 ? 221 THR A O     1 
ATOM   1540 C  CB    . THR A 1 221 ? 29.37700  29.77200  38.54800  1.000 319.62000 ? 221 THR A CB    1 
ATOM   1541 O  OG1   . THR A 1 221 ? 30.80900  29.66000  38.56000  1.000 326.51000 ? 221 THR A OG1   1 
ATOM   1542 C  CG2   . THR A 1 221 ? 28.87000  29.73100  39.97500  1.000 310.19000 ? 221 THR A CG2   1 
ATOM   1543 N  N     . GLN A 1 222 ? 28.76300  28.52200  35.31900  1.000 286.95000 ? 222 GLN A N     1 
ATOM   1544 C  CA    . GLN A 1 222 ? 29.39800  28.61400  34.02200  1.000 284.70000 ? 222 GLN A CA    1 
ATOM   1545 C  C     . GLN A 1 222 ? 29.08000  29.98300  33.49100  1.000 285.15000 ? 222 GLN A C     1 
ATOM   1546 O  O     . GLN A 1 222 ? 27.91000  30.35900  33.39000  1.000 289.68000 ? 222 GLN A O     1 
ATOM   1547 C  CB    . GLN A 1 222 ? 28.93500  27.53500  33.05800  1.000 286.33000 ? 222 GLN A CB    1 
ATOM   1548 C  CG    . GLN A 1 222 ? 30.12400  27.00400  32.28400  1.000 289.36000 ? 222 GLN A CG    1 
ATOM   1549 C  CD    . GLN A 1 222 ? 29.79400  26.48600  30.89400  1.000 293.29000 ? 222 GLN A CD    1 
ATOM   1550 O  OE1   . GLN A 1 222 ? 28.84200  25.71900  30.68500  1.000 296.40000 ? 222 GLN A OE1   1 
ATOM   1551 N  NE2   . GLN A 1 222 ? 30.59900  26.90200  29.92100  1.000 291.57000 ? 222 GLN A NE2   1 
ATOM   1552 N  N     . ILE A 1 223 ? 30.10900  30.72400  33.17600  1.000 283.54000 ? 223 ILE A N     1 
ATOM   1553 C  CA    . ILE A 1 223 ? 29.94900  32.11500  32.83100  1.000 285.86000 ? 223 ILE A CA    1 
ATOM   1554 C  C     . ILE A 1 223 ? 30.19700  32.28500  31.34100  1.000 293.58000 ? 223 ILE A C     1 
ATOM   1555 O  O     . ILE A 1 223 ? 31.22600  31.84800  30.80900  1.000 295.35000 ? 223 ILE A O     1 
ATOM   1556 C  CB    . ILE A 1 223 ? 30.86400  33.00100  33.68600  1.000 288.16000 ? 223 ILE A CB    1 
ATOM   1557 C  CG1   . ILE A 1 223 ? 30.30400  33.02800  35.10400  1.000 285.84000 ? 223 ILE A CG1   1 
ATOM   1558 C  CG2   . ILE A 1 223 ? 31.03500  34.37300  33.05400  1.000 296.53000 ? 223 ILE A CG2   1 
ATOM   1559 C  CD1   . ILE A 1 223 ? 30.77600  34.18700  35.96200  1.000 289.49000 ? 223 ILE A CD1   1 
ATOM   1560 N  N     . LEU A 1 224 ? 29.22700  32.90000  30.66400  1.000 294.34000 ? 224 LEU A N     1 
ATOM   1561 C  CA    . LEU A 1 224 ? 29.24400  33.11200  29.22500  1.000 290.40000 ? 224 LEU A CA    1 
ATOM   1562 C  C     . LEU A 1 224 ? 29.07700  34.59300  28.93300  1.000 297.39000 ? 224 LEU A C     1 
ATOM   1563 O  O     . LEU A 1 224 ? 28.50300  35.34500  29.71500  1.000 304.68000 ? 224 LEU A O     1 
ATOM   1564 C  CB    . LEU A 1 224 ? 28.13500  32.35600  28.51200  1.000 288.06000 ? 224 LEU A CB    1 
ATOM   1565 C  CG    . LEU A 1 224 ? 28.12300  30.90100  28.91800  1.000 285.43000 ? 224 LEU A CG    1 
ATOM   1566 C  CD1   . LEU A 1 224 ? 26.91600  30.17600  28.32900  1.000 292.68000 ? 224 LEU A CD1   1 
ATOM   1567 C  CD2   . LEU A 1 224 ? 29.45200  30.25800  28.50900  1.000 287.42000 ? 224 LEU A CD2   1 
ATOM   1568 N  N     . ARG A 1 225 ? 29.56300  35.01900  27.78200  1.000 290.86000 ? 225 ARG A N     1 
ATOM   1569 C  CA    . ARG A 1 225 ? 29.36000  36.39000  27.33500  1.000 294.69000 ? 225 ARG A CA    1 
ATOM   1570 C  C     . ARG A 1 225 ? 28.29700  36.45800  26.25400  1.000 294.60000 ? 225 ARG A C     1 
ATOM   1571 O  O     . ARG A 1 225 ? 28.29900  35.63600  25.31700  1.000 291.76000 ? 225 ARG A O     1 
ATOM   1572 C  CB    . ARG A 1 225 ? 30.65000  36.98100  26.80100  1.000 294.33000 ? 225 ARG A CB    1 
ATOM   1573 C  CG    . ARG A 1 225 ? 30.96400  38.29500  27.41800  1.000 300.44000 ? 225 ARG A CG    1 
ATOM   1574 C  CD    . ARG A 1 225 ? 30.91300  39.34200  26.34100  1.000 302.70000 ? 225 ARG A CD    1 
ATOM   1575 N  NE    . ARG A 1 225 ? 31.52100  38.88700  25.08800  1.000 301.94000 ? 225 ARG A NE    1 
ATOM   1576 C  CZ    . ARG A 1 225 ? 32.83100  38.81800  24.90000  1.000 304.39000 ? 225 ARG A CZ    1 
ATOM   1577 N  NH1   . ARG A 1 225 ? 33.64000  39.11700  25.89900  1.000 314.79000 ? 225 ARG A NH1   1 
ATOM   1578 N  NH2   . ARG A 1 225 ? 33.28900  38.42100  23.73500  1.000 299.91000 ? 225 ARG A NH2   1 
ATOM   1579 N  N     . GLU A 1 226 ? 27.42200  37.46500  26.37900  1.000 296.57000 ? 226 GLU A N     1 
ATOM   1580 C  CA    . GLU A 1 226 ? 26.41900  37.66300  25.35300  1.000 295.52000 ? 226 GLU A CA    1 
ATOM   1581 C  C     . GLU A 1 226 ? 27.06300  37.77700  23.97700  1.000 289.22000 ? 226 GLU A C     1 
ATOM   1582 O  O     . GLU A 1 226 ? 26.55100  37.22000  22.99900  1.000 290.07000 ? 226 GLU A O     1 
ATOM   1583 C  CB    . GLU A 1 226 ? 25.59300  38.90400  25.68200  1.000 300.66000 ? 226 GLU A CB    1 
ATOM   1584 C  CG    . GLU A 1 226 ? 24.16100  38.57100  26.18700  1.000 299.10000 ? 226 GLU A CG    1 
ATOM   1585 C  CD    . GLU A 1 226 ? 23.42900  39.75300  26.83800  1.000 304.80000 ? 226 GLU A CD    1 
ATOM   1586 O  OE1   . GLU A 1 226 ? 22.53100  39.49600  27.67800  1.000 303.51000 ? 226 GLU A OE1   1 
ATOM   1587 O  OE2   . GLU A 1 226 ? 23.73400  40.92700  26.53100  1.000 311.39000 ? 226 GLU A OE2   1 
ATOM   1588 N  N     . SER A 1 227 ? 28.20800  38.45200  23.88100  1.000 270.75000 ? 227 SER A N     1 
ATOM   1589 C  CA    . SER A 1 227 ? 28.82200  38.54500  22.56800  1.000 271.13000 ? 227 SER A CA    1 
ATOM   1590 C  C     . SER A 1 227 ? 29.14800  37.17300  22.01700  1.000 274.42000 ? 227 SER A C     1 
ATOM   1591 O  O     . SER A 1 227 ? 28.88400  36.89200  20.85500  1.000 271.25000 ? 227 SER A O     1 
ATOM   1592 C  CB    . SER A 1 227 ? 30.07900  39.36100  22.60100  1.000 278.93000 ? 227 SER A CB    1 
ATOM   1593 O  OG    . SER A 1 227 ? 31.09400  38.49200  23.03700  1.000 283.87000 ? 227 SER A OG    1 
ATOM   1594 N  N     . THR A 1 228 ? 29.68400  36.28900  22.83200  1.000 282.86000 ? 228 THR A N     1 
ATOM   1595 C  CA    . THR A 1 228 ? 30.15100  35.03500  22.26500  1.000 271.38000 ? 228 THR A CA    1 
ATOM   1596 C  C     . THR A 1 228 ? 29.00800  34.16700  21.74800  1.000 272.26000 ? 228 THR A C     1 
ATOM   1597 O  O     . THR A 1 228 ? 29.11100  33.61400  20.65000  1.000 274.89000 ? 228 THR A O     1 
ATOM   1598 C  CB    . THR A 1 228 ? 31.00200  34.28800  23.28700  1.000 286.08000 ? 228 THR A CB    1 
ATOM   1599 O  OG1   . THR A 1 228 ? 31.40200  35.19100  24.32600  1.000 290.16000 ? 228 THR A OG1   1 
ATOM   1600 C  CG2   . THR A 1 228 ? 32.26200  33.78100  22.63400  1.000 285.30000 ? 228 THR A CG2   1 
ATOM   1601 N  N     . LEU A 1 229 ? 27.90700  34.04800  22.49100  1.000 272.25000 ? 229 LEU A N     1 
ATOM   1602 C  CA    . LEU A 1 229 ? 26.86700  33.11400  22.06300  1.000 272.03000 ? 229 LEU A CA    1 
ATOM   1603 C  C     . LEU A 1 229 ? 26.08700  33.63400  20.87600  1.000 276.53000 ? 229 LEU A C     1 
ATOM   1604 O  O     . LEU A 1 229 ? 25.35900  32.87300  20.23000  1.000 287.53000 ? 229 LEU A O     1 
ATOM   1605 C  CB    . LEU A 1 229 ? 25.89000  32.83800  23.19900  1.000 279.27000 ? 229 LEU A CB    1 
ATOM   1606 C  CG    . LEU A 1 229 ? 26.60600  32.54800  24.49700  1.000 293.40000 ? 229 LEU A CG    1 
ATOM   1607 C  CD1   . LEU A 1 229 ? 25.61700  32.48100  25.65300  1.000 299.27000 ? 229 LEU A CD1   1 
ATOM   1608 C  CD2   . LEU A 1 229 ? 27.35800  31.24800  24.32300  1.000 287.99000 ? 229 LEU A CD2   1 
ATOM   1609 N  N     . ALA A 1 230 ? 26.15800  34.93100  20.62200  1.000 278.47000 ? 230 ALA A N     1 
ATOM   1610 C  CA    . ALA A 1 230 ? 25.38400  35.56800  19.56200  1.000 293.59000 ? 230 ALA A CA    1 
ATOM   1611 C  C     . ALA A 1 230 ? 26.26500  36.46400  18.70300  1.000 305.72000 ? 230 ALA A C     1 
ATOM   1612 O  O     . ALA A 1 230 ? 25.85700  37.56000  18.31900  1.000 316.36000 ? 230 ALA A O     1 
ATOM   1613 C  CB    . ALA A 1 230 ? 24.21500  36.36700  20.14500  1.000 299.69000 ? 230 ALA A CB    1 
ATOM   1614 N  N     . TRP A 1 231 ? 27.46800  35.98600  18.37500  1.000 308.27000 ? 231 TRP A N     1 
ATOM   1615 C  CA    . TRP A 1 231 ? 28.53100  36.85500  17.87700  1.000 311.51000 ? 231 TRP A CA    1 
ATOM   1616 C  C     . TRP A 1 231 ? 28.25400  37.43400  16.48100  1.000 307.31000 ? 231 TRP A C     1 
ATOM   1617 O  O     . TRP A 1 231 ? 28.88600  38.43300  16.10500  1.000 301.10000 ? 231 TRP A O     1 
ATOM   1618 C  CB    . TRP A 1 231 ? 29.83900  36.06900  17.93000  1.000 308.27000 ? 231 TRP A CB    1 
ATOM   1619 C  CG    . TRP A 1 231 ? 29.79700  34.86000  17.07300  1.000 302.65000 ? 231 TRP A CG    1 
ATOM   1620 C  CD1   . TRP A 1 231 ? 29.34600  33.60500  17.40100  1.000 301.45000 ? 231 TRP A CD1   1 
ATOM   1621 C  CD2   . TRP A 1 231 ? 30.16400  34.80800  15.70900  1.000 294.19000 ? 231 TRP A CD2   1 
ATOM   1622 N  NE1   . TRP A 1 231 ? 29.42800  32.77400  16.30800  1.000 294.23000 ? 231 TRP A NE1   1 
ATOM   1623 C  CE2   . TRP A 1 231 ? 29.93000  33.49100  15.25800  1.000 295.20000 ? 231 TRP A CE2   1 
ATOM   1624 C  CE3   . TRP A 1 231 ? 30.67900  35.74900  14.82100  1.000 297.49000 ? 231 TRP A CE3   1 
ATOM   1625 C  CZ2   . TRP A 1 231 ? 30.20000  33.09500  13.96900  1.000 299.10000 ? 231 TRP A CZ2   1 
ATOM   1626 C  CZ3   . TRP A 1 231 ? 30.93400  35.36200  13.54600  1.000 305.26000 ? 231 TRP A CZ3   1 
ATOM   1627 C  CH2   . TRP A 1 231 ? 30.70100  34.04000  13.12500  1.000 305.02000 ? 231 TRP A CH2   1 
ATOM   1628 N  N     . ARG A 1 232 ? 27.31300  36.86100  15.72000  1.000 308.40000 ? 232 ARG A N     1 
ATOM   1629 C  CA    . ARG A 1 232 ? 26.91700  37.44500  14.44600  1.000 304.84000 ? 232 ARG A CA    1 
ATOM   1630 C  C     . ARG A 1 232 ? 25.79900  38.46700  14.58100  1.000 306.07000 ? 232 ARG A C     1 
ATOM   1631 O  O     . ARG A 1 232 ? 25.46700  39.14500  13.60300  1.000 313.36000 ? 232 ARG A O     1 
ATOM   1632 C  CB    . ARG A 1 232 ? 26.51400  36.35100  13.44100  1.000 312.58000 ? 232 ARG A CB    1 
ATOM   1633 C  CG    . ARG A 1 232 ? 25.91700  35.04500  14.01700  1.000 305.82000 ? 232 ARG A CG    1 
ATOM   1634 C  CD    . ARG A 1 232 ? 26.31800  33.83400  13.15700  1.000 309.98000 ? 232 ARG A CD    1 
ATOM   1635 N  NE    . ARG A 1 232 ? 26.77300  34.26700  11.82700  1.000 338.08000 ? 232 ARG A NE    1 
ATOM   1636 C  CZ    . ARG A 1 232 ? 27.66200  33.61300  11.07500  1.000 333.03000 ? 232 ARG A CZ    1 
ATOM   1637 N  NH1   . ARG A 1 232 ? 28.19300  32.47900  11.52200  1.000 321.83000 ? 232 ARG A NH1   1 
ATOM   1638 N  NH2   . ARG A 1 232 ? 28.01500  34.08700  9.87800   1.000 320.89000 ? 232 ARG A NH2   1 
ATOM   1639 N  N     . ASP A 1 233 ? 25.22000  38.59900  15.76300  1.000 308.33000 ? 233 ASP A N     1 
ATOM   1640 C  CA    . ASP A 1 233 ? 24.21700  39.61000  16.03500  1.000 313.32000 ? 233 ASP A CA    1 
ATOM   1641 C  C     . ASP A 1 233 ? 24.81300  40.80200  16.78900  1.000 314.68000 ? 233 ASP A C     1 
ATOM   1642 O  O     . ASP A 1 233 ? 24.07200  41.62800  17.33900  1.000 312.00000 ? 233 ASP A O     1 
ATOM   1643 C  CB    . ASP A 1 233 ? 23.05600  38.96800  16.80500  1.000 317.36000 ? 233 ASP A CB    1 
ATOM   1644 C  CG    . ASP A 1 233 ? 22.32800  37.87800  15.98800  1.000 305.64000 ? 233 ASP A CG    1 
ATOM   1645 O  OD1   . ASP A 1 233 ? 21.87900  38.16200  14.86200  1.000 309.12000 ? 233 ASP A OD1   1 
ATOM   1646 O  OD2   . ASP A 1 233 ? 22.19900  36.73500  16.47900  1.000 304.72000 ? 233 ASP A OD2   1 
ATOM   1647 N  N     . PHE A 1 234 ? 26.14700  40.89600  16.82600  1.000 304.23000 ? 234 PHE A N     1 
ATOM   1648 C  CA    . PHE A 1 234 ? 26.88100  41.97800  17.48300  1.000 300.07000 ? 234 PHE A CA    1 
ATOM   1649 C  C     . PHE A 1 234 ? 27.79000  42.58300  16.40400  1.000 297.76000 ? 234 PHE A C     1 
ATOM   1650 O  O     . PHE A 1 234 ? 29.02100  42.51800  16.47800  1.000 301.48000 ? 234 PHE A O     1 
ATOM   1651 C  CB    . PHE A 1 234 ? 27.70700  41.47300  18.69300  1.000 308.85000 ? 234 PHE A CB    1 
ATOM   1652 C  CG    . PHE A 1 234 ? 26.95900  41.39200  20.04700  1.000 298.66000 ? 234 PHE A CG    1 
ATOM   1653 C  CD1   . PHE A 1 234 ? 27.53300  41.91300  21.21300  1.000 291.41000 ? 234 PHE A CD1   1 
ATOM   1654 C  CD2   . PHE A 1 234 ? 25.72700  40.75700  20.16600  1.000 295.51000 ? 234 PHE A CD2   1 
ATOM   1655 C  CE1   . PHE A 1 234 ? 26.89100  41.82700  22.45000  1.000 286.75000 ? 234 PHE A CE1   1 
ATOM   1656 C  CE2   . PHE A 1 234 ? 25.08500  40.67500  21.41000  1.000 295.53000 ? 234 PHE A CE2   1 
ATOM   1657 C  CZ    . PHE A 1 234 ? 25.67000  41.21000  22.54400  1.000 290.72000 ? 234 PHE A CZ    1 
ATOM   1658 N  N     . LYS A 1 235 ? 27.16800  43.15600  15.38200  1.000 301.91000 ? 235 LYS A N     1 
ATOM   1659 C  CA    . LYS A 1 235 ? 27.91700  43.82700  14.33500  1.000 313.17000 ? 235 LYS A CA    1 
ATOM   1660 C  C     . LYS A 1 235 ? 28.62400  45.06300  14.90300  1.000 316.78000 ? 235 LYS A C     1 
ATOM   1661 O  O     . LYS A 1 235 ? 28.22400  45.60900  15.93800  1.000 304.41000 ? 235 LYS A O     1 
ATOM   1662 C  CB    . LYS A 1 235 ? 26.96700  44.19000  13.18500  1.000 320.55000 ? 235 LYS A CB    1 
ATOM   1663 C  CG    . LYS A 1 235 ? 25.90100  43.10300  12.90200  1.000 309.15000 ? 235 LYS A CG    1 
ATOM   1664 C  CD    . LYS A 1 235 ? 26.35700  42.05600  11.88500  1.000 305.48000 ? 235 LYS A CD    1 
ATOM   1665 C  CE    . LYS A 1 235 ? 25.17100  41.20100  11.44800  1.000 307.21000 ? 235 LYS A CE    1 
ATOM   1666 N  NZ    . LYS A 1 235 ? 24.86600  41.33600  10.00800  1.000 312.98000 ? 235 LYS A NZ    1 
ATOM   1667 N  N     . ASN A 1 236 ? 29.73300  45.45400  14.24300  1.000 333.11000 ? 236 ASN A N     1 
ATOM   1668 C  CA    . ASN A 1 236 ? 30.47700  46.68100  14.52700  1.000 337.27000 ? 236 ASN A CA    1 
ATOM   1669 C  C     . ASN A 1 236 ? 29.92300  47.83000  13.67900  1.000 342.07000 ? 236 ASN A C     1 
ATOM   1670 O  O     . ASN A 1 236 ? 28.88300  47.69200  13.02400  1.000 341.07000 ? 236 ASN A O     1 
ATOM   1671 C  CB    . ASN A 1 236 ? 31.99400  46.47500  14.32400  1.000 337.80000 ? 236 ASN A CB    1 
ATOM   1672 C  CG    . ASN A 1 236 ? 32.44100  46.39400  12.83700  1.000 343.62000 ? 236 ASN A CG    1 
ATOM   1673 O  OD1   . ASN A 1 236 ? 31.63700  46.49200  11.91200  1.000 348.79000 ? 236 ASN A OD1   1 
ATOM   1674 N  ND2   . ASN A 1 236 ? 33.74600  46.21300  12.62400  1.000 344.24000 ? 236 ASN A ND2   1 
ATOM   1675 N  N     . THR A 1 237 ? 30.61200  48.98500  13.68400  1.000 346.63000 ? 237 THR A N     1 
ATOM   1676 C  CA    . THR A 1 237 ? 30.12600  50.13400  12.92200  1.000 345.90000 ? 237 THR A CA    1 
ATOM   1677 C  C     . THR A 1 237 ? 30.11600  49.82300  11.42900  1.000 345.42000 ? 237 THR A C     1 
ATOM   1678 O  O     . THR A 1 237 ? 29.17300  50.18900  10.70900  1.000 343.63000 ? 237 THR A O     1 
ATOM   1679 C  CB    . THR A 1 237 ? 30.97400  51.37700  13.22800  1.000 344.91000 ? 237 THR A CB    1 
ATOM   1680 O  OG1   . THR A 1 237 ? 32.36500  51.04700  13.21600  1.000 339.54000 ? 237 THR A OG1   1 
ATOM   1681 C  CG2   . THR A 1 237 ? 30.61900  51.97200  14.58300  1.000 339.44000 ? 237 THR A CG2   1 
ATOM   1682 N  N     . PHE A 1 238 ? 31.13600  49.09200  10.96300  1.000 344.28000 ? 238 PHE A N     1 
ATOM   1683 C  CA    . PHE A 1 238 ? 31.20400  48.67600  9.56600   1.000 341.01000 ? 238 PHE A CA    1 
ATOM   1684 C  C     . PHE A 1 238 ? 30.06200  47.76000  9.16000   1.000 337.29000 ? 238 PHE A C     1 
ATOM   1685 O  O     . PHE A 1 238 ? 29.74900  47.68000  7.97200   1.000 339.66000 ? 238 PHE A O     1 
ATOM   1686 C  CB    . PHE A 1 238 ? 32.51900  47.96000  9.27700   1.000 339.85000 ? 238 PHE A CB    1 
ATOM   1687 C  CG    . PHE A 1 238 ? 33.69000  48.87700  9.13700   1.000 339.48000 ? 238 PHE A CG    1 
ATOM   1688 C  CD1   . PHE A 1 238 ? 34.97600  48.36100  9.08500   1.000 343.52000 ? 238 PHE A CD1   1 
ATOM   1689 C  CD2   . PHE A 1 238 ? 33.51900  50.24300  9.05200   1.000 339.99000 ? 238 PHE A CD2   1 
ATOM   1690 C  CE1   . PHE A 1 238 ? 36.06200  49.20300  8.95600   1.000 346.97000 ? 238 PHE A CE1   1 
ATOM   1691 C  CE2   . PHE A 1 238 ? 34.60100  51.08300  8.92400   1.000 342.40000 ? 238 PHE A CE2   1 
ATOM   1692 C  CZ    . PHE A 1 238 ? 35.87600  50.56100  8.87800   1.000 341.08000 ? 238 PHE A CZ    1 
ATOM   1693 N  N     . GLY A 1 239 ? 29.43700  47.06300  10.09800  1.000 334.90000 ? 239 GLY A N     1 
ATOM   1694 C  CA    . GLY A 1 239 ? 28.41500  46.09600  9.75500   1.000 330.46000 ? 239 GLY A CA    1 
ATOM   1695 C  C     . GLY A 1 239 ? 28.86800  44.65300  9.72600   1.000 331.58000 ? 239 GLY A C     1 
ATOM   1696 O  O     . GLY A 1 239 ? 28.01100  43.75600  9.64600   1.000 324.19000 ? 239 GLY A O     1 
ATOM   1697 N  N     . ALA A 1 240 ? 30.17700  44.41100  9.76900   1.000 327.85000 ? 240 ALA A N     1 
ATOM   1698 C  CA    . ALA A 1 240 ? 30.67200  43.09900  10.09800  1.000 321.17000 ? 240 ALA A CA    1 
ATOM   1699 C  C     . ALA A 1 240 ? 30.66300  42.90400  11.62100  1.000 331.97000 ? 240 ALA A C     1 
ATOM   1700 O  O     . ALA A 1 240 ? 30.68200  43.88000  12.38600  1.000 338.02000 ? 240 ALA A O     1 
ATOM   1701 C  CB    . ALA A 1 240 ? 32.08400  42.89300  9.53300   1.000 317.95000 ? 240 ALA A CB    1 
ATOM   1702 N  N     . PRO A 1 241 ? 30.65400  41.64600  12.08900  1.000 327.24000 ? 241 PRO A N     1 
ATOM   1703 C  CA    . PRO A 1 241 ? 30.64900  41.38500  13.54800  1.000 311.34000 ? 241 PRO A CA    1 
ATOM   1704 C  C     . PRO A 1 241 ? 31.95900  41.76200  14.22300  1.000 300.46000 ? 241 PRO A C     1 
ATOM   1705 O  O     . PRO A 1 241 ? 33.04400  41.52900  13.68700  1.000 299.68000 ? 241 PRO A O     1 
ATOM   1706 C  CB    . PRO A 1 241 ? 30.42100  39.87600  13.66400  1.000 298.21000 ? 241 PRO A CB    1 
ATOM   1707 C  CG    . PRO A 1 241 ? 30.01000  39.44000  12.28900  1.000 311.78000 ? 241 PRO A CG    1 
ATOM   1708 C  CD    . PRO A 1 241 ? 30.52700  40.41900  11.28800  1.000 321.39000 ? 241 PRO A CD    1 
ATOM   1709 N  N     . ILE A 1 242 ? 31.86300  42.34700  15.42500  1.000 287.02000 ? 242 ILE A N     1 
ATOM   1710 C  CA    . ILE A 1 242 ? 33.08000  42.90100  16.03600  1.000 281.74000 ? 242 ILE A CA    1 
ATOM   1711 C  C     . ILE A 1 242 ? 34.14100  41.82400  16.19200  1.000 276.29000 ? 242 ILE A C     1 
ATOM   1712 O  O     . ILE A 1 242 ? 35.32800  42.02900  15.90400  1.000 272.79000 ? 242 ILE A O     1 
ATOM   1713 C  CB    . ILE A 1 242 ? 32.78100  43.57000  17.38500  1.000 273.25000 ? 242 ILE A CB    1 
ATOM   1714 C  CG1   . ILE A 1 242 ? 31.66100  44.56100  17.20400  1.000 278.85000 ? 242 ILE A CG1   1 
ATOM   1715 C  CG2   . ILE A 1 242 ? 34.03400  44.27400  17.88000  1.000 276.69000 ? 242 ILE A CG2   1 
ATOM   1716 C  CD1   . ILE A 1 242 ? 31.27200  45.35200  18.41500  1.000 290.40000 ? 242 ILE A CD1   1 
ATOM   1717 N  N     . ARG A 1 243 ? 33.72700  40.65800  16.64100  1.000 282.49000 ? 243 ARG A N     1 
ATOM   1718 C  CA    . ARG A 1 243 ? 34.58300  39.48900  16.72000  1.000 279.83000 ? 243 ARG A CA    1 
ATOM   1719 C  C     . ARG A 1 243 ? 33.89900  38.40600  15.90400  1.000 277.04000 ? 243 ARG A C     1 
ATOM   1720 O  O     . ARG A 1 243 ? 32.68600  38.18700  16.04300  1.000 277.24000 ? 243 ARG A O     1 
ATOM   1721 C  CB    . ARG A 1 243 ? 34.80000  39.05900  18.17800  1.000 297.87000 ? 243 ARG A CB    1 
ATOM   1722 C  CG    . ARG A 1 243 ? 35.37700  40.15500  19.11600  1.000 311.39000 ? 243 ARG A CG    1 
ATOM   1723 C  CD    . ARG A 1 243 ? 35.51500  39.67600  20.61100  1.000 321.16000 ? 243 ARG A CD    1 
ATOM   1724 N  NE    . ARG A 1 243 ? 35.95500  40.72300  21.56700  1.000 317.82000 ? 243 ARG A NE    1 
ATOM   1725 C  CZ    . ARG A 1 243 ? 36.36700  40.53800  22.83400  1.000 320.98000 ? 243 ARG A CZ    1 
ATOM   1726 N  NH1   . ARG A 1 243 ? 36.41000  39.33900  23.37400  1.000 313.00000 ? 243 ARG A NH1   1 
ATOM   1727 N  NH2   . ARG A 1 243 ? 36.74200  41.59100  23.57000  1.000 310.86000 ? 243 ARG A NH2   1 
ATOM   1728 N  N     . ASP A 1 244 ? 34.65600  37.79200  15.00900  1.000 291.63000 ? 244 ASP A N     1 
ATOM   1729 C  CA    . ASP A 1 244 ? 34.11300  36.91600  13.97900  1.000 304.48000 ? 244 ASP A CA    1 
ATOM   1730 C  C     . ASP A 1 244 ? 34.63700  35.51300  14.25900  1.000 303.00000 ? 244 ASP A C     1 
ATOM   1731 O  O     . ASP A 1 244 ? 35.85100  35.29900  14.34500  1.000 302.98000 ? 244 ASP A O     1 
ATOM   1732 C  CB    . ASP A 1 244 ? 34.48600  37.47000  12.59200  1.000 318.36000 ? 244 ASP A CB    1 
ATOM   1733 C  CG    . ASP A 1 244 ? 34.23100  36.49100  11.43100  1.000 324.38000 ? 244 ASP A CG    1 
ATOM   1734 O  OD1   . ASP A 1 244 ? 35.14800  35.68900  11.12500  1.000 319.77000 ? 244 ASP A OD1   1 
ATOM   1735 O  OD2   . ASP A 1 244 ? 33.13900  36.55200  10.80200  1.000 327.62000 ? 244 ASP A OD2   1 
ATOM   1736 N  N     . PHE A 1 245 ? 33.71200  34.57500  14.46300  1.000 306.73000 ? 245 PHE A N     1 
ATOM   1737 C  CA    . PHE A 1 245 ? 34.02200  33.24800  14.96900  1.000 301.22000 ? 245 PHE A CA    1 
ATOM   1738 C  C     . PHE A 1 245 ? 33.62900  32.14800  13.99100  1.000 300.43000 ? 245 PHE A C     1 
ATOM   1739 O  O     . PHE A 1 245 ? 33.59800  30.97300  14.36700  1.000 297.23000 ? 245 PHE A O     1 
ATOM   1740 C  CB    . PHE A 1 245 ? 33.32900  33.03300  16.31500  1.000 304.57000 ? 245 PHE A CB    1 
ATOM   1741 C  CG    . PHE A 1 245 ? 33.93700  33.82000  17.46800  1.000 315.20000 ? 245 PHE A CG    1 
ATOM   1742 C  CD1   . PHE A 1 245 ? 33.14900  34.22000  18.54500  1.000 320.34000 ? 245 PHE A CD1   1 
ATOM   1743 C  CD2   . PHE A 1 245 ? 35.29500  34.13600  17.49600  1.000 324.08000 ? 245 PHE A CD2   1 
ATOM   1744 C  CE1   . PHE A 1 245 ? 33.69700  34.93100  19.61800  1.000 319.48000 ? 245 PHE A CE1   1 
ATOM   1745 C  CE2   . PHE A 1 245 ? 35.85000  34.84900  18.57400  1.000 324.23000 ? 245 PHE A CE2   1 
ATOM   1746 C  CZ    . PHE A 1 245 ? 35.04900  35.24100  19.63100  1.000 321.81000 ? 245 PHE A CZ    1 
ATOM   1747 N  N     . SER A 1 246 ? 33.34000  32.50700  12.73700  1.000 309.23000 ? 246 SER A N     1 
ATOM   1748 C  CA    . SER A 1 246 ? 32.96300  31.50700  11.74100  1.000 310.04000 ? 246 SER A CA    1 
ATOM   1749 C  C     . SER A 1 246 ? 34.03200  30.44600  11.59400  1.000 306.66000 ? 246 SER A C     1 
ATOM   1750 O  O     . SER A 1 246 ? 33.72900  29.30700  11.21900  1.000 302.24000 ? 246 SER A O     1 
ATOM   1751 C  CB    . SER A 1 246 ? 32.70400  32.15600  10.37600  1.000 306.65000 ? 246 SER A CB    1 
ATOM   1752 O  OG    . SER A 1 246 ? 33.86500  32.81300  9.88500   1.000 307.28000 ? 246 SER A OG    1 
ATOM   1753 N  N     . LYS A 1 247 ? 35.28500  30.79400  11.88000  1.000 305.76000 ? 247 LYS A N     1 
ATOM   1754 C  CA    . LYS A 1 247 ? 36.34900  29.82000  11.69700  1.000 306.48000 ? 247 LYS A CA    1 
ATOM   1755 C  C     . LYS A 1 247 ? 36.24200  28.70000  12.72600  1.000 300.60000 ? 247 LYS A C     1 
ATOM   1756 O  O     . LYS A 1 247 ? 36.60400  27.55500  12.44400  1.000 301.29000 ? 247 LYS A O     1 
ATOM   1757 C  CB    . LYS A 1 247 ? 37.71900  30.52400  11.73600  1.000 310.28000 ? 247 LYS A CB    1 
ATOM   1758 C  CG    . LYS A 1 247 ? 38.24200  30.93200  10.33100  1.000 307.74000 ? 247 LYS A CG    1 
ATOM   1759 C  CD    . LYS A 1 247 ? 39.35400  31.98500  10.38300  1.000 306.33000 ? 247 LYS A CD    1 
ATOM   1760 C  CE    . LYS A 1 247 ? 40.67100  31.44700  9.83400   1.000 306.52000 ? 247 LYS A CE    1 
ATOM   1761 N  NZ    . LYS A 1 247 ? 40.62100  31.36300  8.35700   1.000 301.29000 ? 247 LYS A NZ    1 
ATOM   1762 N  N     . ILE A 1 248 ? 35.71500  28.98600  13.91400  1.000 295.87000 ? 248 ILE A N     1 
ATOM   1763 C  CA    . ILE A 1 248 ? 35.92700  28.05400  15.02100  1.000 294.86000 ? 248 ILE A CA    1 
ATOM   1764 C  C     . ILE A 1 248 ? 34.62100  27.73400  15.76900  1.000 291.12000 ? 248 ILE A C     1 
ATOM   1765 O  O     . ILE A 1 248 ? 34.65700  27.30500  16.92000  1.000 285.33000 ? 248 ILE A O     1 
ATOM   1766 C  CB    . ILE A 1 248 ? 37.02400  28.56900  15.98700  1.000 299.03000 ? 248 ILE A CB    1 
ATOM   1767 C  CG1   . ILE A 1 248 ? 36.60500  29.83000  16.75900  1.000 307.50000 ? 248 ILE A CG1   1 
ATOM   1768 C  CG2   . ILE A 1 248 ? 38.30200  28.91200  15.24100  1.000 301.20000 ? 248 ILE A CG2   1 
ATOM   1769 C  CD1   . ILE A 1 248 ? 37.38100  30.02900  18.08800  1.000 318.56000 ? 248 ILE A CD1   1 
ATOM   1770 N  N     . GLU A 1 249 ? 33.46400  27.89300  15.11100  1.000 283.39000 ? 249 GLU A N     1 
ATOM   1771 C  CA    . GLU A 1 249 ? 32.21100  28.01500  15.85300  1.000 281.60000 ? 249 GLU A CA    1 
ATOM   1772 C  C     . GLU A 1 249 ? 31.85400  26.71600  16.56400  1.000 276.53000 ? 249 GLU A C     1 
ATOM   1773 O  O     . GLU A 1 249 ? 31.33300  26.73300  17.68500  1.000 277.57000 ? 249 GLU A O     1 
ATOM   1774 C  CB    . GLU A 1 249 ? 31.09200  28.44100  14.90900  1.000 293.74000 ? 249 GLU A CB    1 
ATOM   1775 C  CG    . GLU A 1 249 ? 29.98100  29.30800  15.54900  1.000 292.43000 ? 249 GLU A CG    1 
ATOM   1776 C  CD    . GLU A 1 249 ? 28.78100  29.47400  14.63300  1.000 298.24000 ? 249 GLU A CD    1 
ATOM   1777 O  OE1   . GLU A 1 249 ? 27.70800  29.91800  15.07500  1.000 308.09000 ? 249 GLU A OE1   1 
ATOM   1778 O  OE2   . GLU A 1 249 ? 28.91400  29.15000  13.44800  1.000 302.20000 ? 249 GLU A OE2   1 
ATOM   1779 N  N     . GLY A 1 250 ? 32.14100  25.58000  15.93600  1.000 277.05000 ? 250 GLY A N     1 
ATOM   1780 C  CA    . GLY A 1 250 ? 31.93300  24.31500  16.60800  1.000 279.06000 ? 250 GLY A CA    1 
ATOM   1781 C  C     . GLY A 1 250 ? 32.92200  24.10400  17.74100  1.000 275.45000 ? 250 GLY A C     1 
ATOM   1782 O  O     . GLY A 1 250 ? 32.58100  23.52100  18.77100  1.000 273.78000 ? 250 GLY A O     1 
ATOM   1783 N  N     . HIS A 1 251 ? 34.17900  24.52700  17.55600  1.000 275.01000 ? 251 HIS A N     1 
ATOM   1784 C  CA    . HIS A 1 251 ? 35.12600  24.42800  18.66400  1.000 278.26000 ? 251 HIS A CA    1 
ATOM   1785 C  C     . HIS A 1 251 ? 34.54800  25.07000  19.91800  1.000 277.18000 ? 251 HIS A C     1 
ATOM   1786 O  O     . HIS A 1 251 ? 34.58500  24.46900  21.00000  1.000 279.03000 ? 251 HIS A O     1 
ATOM   1787 C  CB    . HIS A 1 251 ? 36.46400  25.05400  18.27300  1.000 283.21000 ? 251 HIS A CB    1 
ATOM   1788 C  CG    . HIS A 1 251 ? 37.39600  25.29700  19.42200  1.000 287.94000 ? 251 HIS A CG    1 
ATOM   1789 N  ND1   . HIS A 1 251 ? 37.65000  24.35400  20.39400  1.000 284.87000 ? 251 HIS A ND1   1 
ATOM   1790 C  CD2   . HIS A 1 251 ? 38.15800  26.37200  19.73900  1.000 295.06000 ? 251 HIS A CD2   1 
ATOM   1791 C  CE1   . HIS A 1 251 ? 38.51300  24.84000  21.27100  1.000 291.44000 ? 251 HIS A CE1   1 
ATOM   1792 N  NE2   . HIS A 1 251 ? 38.83900  26.06300  20.89500  1.000 292.99000 ? 251 HIS A NE2   1 
ATOM   1793 N  N     . LEU A 1 252 ? 33.94400  26.25500  19.78200  1.000 278.32000 ? 252 LEU A N     1 
ATOM   1794 C  CA    . LEU A 1 252 ? 33.24700  26.82700  20.92300  1.000 278.05000 ? 252 LEU A CA    1 
ATOM   1795 C  C     . LEU A 1 252 ? 32.33200  25.80700  21.56300  1.000 277.31000 ? 252 LEU A C     1 
ATOM   1796 O  O     . LEU A 1 252 ? 32.48800  25.50300  22.75300  1.000 277.60000 ? 252 LEU A O     1 
ATOM   1797 C  CB    . LEU A 1 252 ? 32.44700  28.05100  20.51300  1.000 279.63000 ? 252 LEU A CB    1 
ATOM   1798 C  CG    . LEU A 1 252 ? 33.26000  29.33900  20.59400  1.000 287.10000 ? 252 LEU A CG    1 
ATOM   1799 C  CD1   . LEU A 1 252 ? 34.35400  29.36900  19.54600  1.000 296.98000 ? 252 LEU A CD1   1 
ATOM   1800 C  CD2   . LEU A 1 252 ? 32.34100  30.57600  20.49600  1.000 298.19000 ? 252 LEU A CD2   1 
ATOM   1801 N  N     . ALA A 1 253 ? 31.40000  25.23300  20.78800  1.000 275.86000 ? 253 ALA A N     1 
ATOM   1802 C  CA    . ALA A 1 253 ? 30.48700  24.27800  21.40200  1.000 275.06000 ? 253 ALA A CA    1 
ATOM   1803 C  C     . ALA A 1 253 ? 31.25700  23.17400  22.11100  1.000 274.37000 ? 253 ALA A C     1 
ATOM   1804 O  O     . ALA A 1 253 ? 30.81800  22.67300  23.15200  1.000 271.52000 ? 253 ALA A O     1 
ATOM   1805 C  CB    . ALA A 1 253 ? 29.53400  23.69300  20.36300  1.000 276.12000 ? 253 ALA A CB    1 
ATOM   1806 N  N     . TRP A 1 254 ? 32.42900  22.80900  21.58500  1.000 280.19000 ? 254 TRP A N     1 
ATOM   1807 C  CA    . TRP A 1 254 ? 33.23300  21.79600  22.25900  1.000 275.41000 ? 254 TRP A CA    1 
ATOM   1808 C  C     . TRP A 1 254 ? 33.67000  22.27500  23.62900  1.000 277.92000 ? 254 TRP A C     1 
ATOM   1809 O  O     . TRP A 1 254 ? 33.49500  21.56700  24.62600  1.000 281.32000 ? 254 TRP A O     1 
ATOM   1810 C  CB    . TRP A 1 254 ? 34.45200  21.41900  21.41900  1.000 278.89000 ? 254 TRP A CB    1 
ATOM   1811 C  CG    . TRP A 1 254 ? 34.20100  20.27300  20.49300  1.000 280.62000 ? 254 TRP A CG    1 
ATOM   1812 C  CD1   . TRP A 1 254 ? 34.32100  20.26600  19.12800  1.000 282.01000 ? 254 TRP A CD1   1 
ATOM   1813 C  CD2   . TRP A 1 254 ? 33.76900  18.96700  20.86400  1.000 278.59000 ? 254 TRP A CD2   1 
ATOM   1814 N  NE1   . TRP A 1 254 ? 33.99200  19.03100  18.62800  1.000 280.21000 ? 254 TRP A NE1   1 
ATOM   1815 C  CE2   . TRP A 1 254 ? 33.64600  18.21700  19.67300  1.000 279.82000 ? 254 TRP A CE2   1 
ATOM   1816 C  CE3   . TRP A 1 254 ? 33.47300  18.35700  22.08900  1.000 275.62000 ? 254 TRP A CE3   1 
ATOM   1817 C  CZ2   . TRP A 1 254 ? 33.24200  16.89700  19.67100  1.000 280.40000 ? 254 TRP A CZ2   1 
ATOM   1818 C  CZ3   . TRP A 1 254 ? 33.07600  17.04500  22.08900  1.000 275.62000 ? 254 TRP A CZ3   1 
ATOM   1819 C  CH2   . TRP A 1 254 ? 32.96500  16.32300  20.88400  1.000 277.22000 ? 254 TRP A CH2   1 
ATOM   1820 N  N     . THR A 1 255 ? 34.21200  23.49200  23.70200  1.000 277.61000 ? 255 THR A N     1 
ATOM   1821 C  CA    . THR A 1 255 ? 34.71700  23.99100  24.97800  1.000 285.51000 ? 255 THR A CA    1 
ATOM   1822 C  C     . THR A 1 255 ? 33.58200  24.18200  25.99100  1.000 289.03000 ? 255 THR A C     1 
ATOM   1823 O  O     . THR A 1 255 ? 33.70600  23.77300  27.15600  1.000 298.56000 ? 255 THR A O     1 
ATOM   1824 C  CB    . THR A 1 255 ? 35.51700  25.27500  24.74300  1.000 293.45000 ? 255 THR A CB    1 
ATOM   1825 O  OG1   . THR A 1 255 ? 36.64600  24.96700  23.92200  1.000 289.23000 ? 255 THR A OG1   1 
ATOM   1826 C  CG2   . THR A 1 255 ? 36.03800  25.89500  26.03800  1.000 302.06000 ? 255 THR A CG2   1 
ATOM   1827 N  N     . ILE A 1 256 ? 32.42800  24.69400  25.54800  1.000 285.32000 ? 256 ILE A N     1 
ATOM   1828 C  CA    . ILE A 1 256 ? 31.38100  25.10400  26.49100  1.000 289.66000 ? 256 ILE A CA    1 
ATOM   1829 C  C     . ILE A 1 256 ? 30.60800  23.89100  27.01500  1.000 280.34000 ? 256 ILE A C     1 
ATOM   1830 O  O     . ILE A 1 256 ? 30.36200  23.75100  28.22000  1.000 278.58000 ? 256 ILE A O     1 
ATOM   1831 C  CB    . ILE A 1 256 ? 30.42300  26.12700  25.84400  1.000 292.67000 ? 256 ILE A CB    1 
ATOM   1832 C  CG1   . ILE A 1 256 ? 31.16900  27.29300  25.18500  1.000 297.49000 ? 256 ILE A CG1   1 
ATOM   1833 C  CG2   . ILE A 1 256 ? 29.41200  26.61200  26.89300  1.000 290.31000 ? 256 ILE A CG2   1 
ATOM   1834 C  CD1   . ILE A 1 256 ? 30.27800  28.25200  24.37000  1.000 299.50000 ? 256 ILE A CD1   1 
ATOM   1835 N  N     . SER A 1 257 ? 30.14800  23.03400  26.11300  1.000 272.68000 ? 257 SER A N     1 
ATOM   1836 C  CA    . SER A 1 257 ? 29.43000  21.84900  26.56100  1.000 270.92000 ? 257 SER A CA    1 
ATOM   1837 C  C     . SER A 1 257 ? 30.32200  20.93000  27.38900  1.000 275.12000 ? 257 SER A C     1 
ATOM   1838 O  O     . SER A 1 257 ? 29.89800  20.45600  28.45000  1.000 276.77000 ? 257 SER A O     1 
ATOM   1839 C  CB    . SER A 1 257 ? 28.84600  21.12200  25.35700  1.000 274.24000 ? 257 SER A CB    1 
ATOM   1840 O  OG    . SER A 1 257 ? 29.07600  21.88700  24.17900  1.000 273.46000 ? 257 SER A OG    1 
ATOM   1841 N  N     . THR A 1 258 ? 31.57900  20.72900  26.95800  1.000 280.32000 ? 258 THR A N     1 
ATOM   1842 C  CA    . THR A 1 258 ? 32.51400  19.91000  27.73000  1.000 282.25000 ? 258 THR A CA    1 
ATOM   1843 C  C     . THR A 1 258 ? 32.67400  20.45500  29.13200  1.000 284.41000 ? 258 THR A C     1 
ATOM   1844 O  O     . THR A 1 258 ? 32.79300  19.69400  30.10200  1.000 285.98000 ? 258 THR A O     1 
ATOM   1845 C  CB    . THR A 1 258 ? 33.90200  19.86400  27.07000  1.000 279.52000 ? 258 THR A CB    1 
ATOM   1846 O  OG1   . THR A 1 258 ? 33.76900  19.72700  25.65400  1.000 272.15000 ? 258 THR A OG1   1 
ATOM   1847 C  CG2   . THR A 1 258 ? 34.70800  18.69900  27.62600  1.000 279.50000 ? 258 THR A CG2   1 
ATOM   1848 N  N     . ALA A 1 259 ? 32.76800  21.77500  29.24400  1.000 284.96000 ? 259 ALA A N     1 
ATOM   1849 C  CA    . ALA A 1 259 ? 32.72500  22.39000  30.55800  1.000 285.44000 ? 259 ALA A CA    1 
ATOM   1850 C  C     . ALA A 1 259 ? 31.32100  22.31100  31.13200  1.000 284.27000 ? 259 ALA A C     1 
ATOM   1851 O  O     . ALA A 1 259 ? 31.13100  21.97900  32.31200  1.000 285.56000 ? 259 ALA A O     1 
ATOM   1852 C  CB    . ALA A 1 259 ? 33.17000  23.83400  30.46100  1.000 289.40000 ? 259 ALA A CB    1 
ATOM   1853 N  N     . ALA A 1 260 ? 30.32500  22.64700  30.30300  1.000 283.98000 ? 260 ALA A N     1 
ATOM   1854 C  CA    . ALA A 1 260 ? 28.93000  22.50100  30.70100  1.000 282.17000 ? 260 ALA A CA    1 
ATOM   1855 C  C     . ALA A 1 260 ? 28.67200  21.10900  31.22200  1.000 279.92000 ? 260 ALA A C     1 
ATOM   1856 O  O     . ALA A 1 260 ? 28.20000  20.93300  32.35300  1.000 283.11000 ? 260 ALA A O     1 
ATOM   1857 C  CB    . ALA A 1 260 ? 27.99500  22.78200  29.52300  1.000 277.89000 ? 260 ALA A CB    1 
ATOM   1858 N  N     . TYR A 1 261 ? 28.99800  20.10900  30.41000  1.000 280.70000 ? 261 TYR A N     1 
ATOM   1859 C  CA    . TYR A 1 261 ? 28.87600  18.72600  30.83700  1.000 279.05000 ? 261 TYR A CA    1 
ATOM   1860 C  C     . TYR A 1 261 ? 29.51800  18.50500  32.20500  1.000 284.03000 ? 261 TYR A C     1 
ATOM   1861 O  O     . TYR A 1 261 ? 28.87900  17.98000  33.12400  1.000 285.79000 ? 261 TYR A O     1 
ATOM   1862 C  CB    . TYR A 1 261 ? 29.50300  17.81500  29.78400  1.000 279.74000 ? 261 TYR A CB    1 
ATOM   1863 C  CG    . TYR A 1 261 ? 29.16400  16.38700  30.04100  1.000 284.06000 ? 261 TYR A CG    1 
ATOM   1864 C  CD1   . TYR A 1 261 ? 30.04400  15.55800  30.72200  1.000 286.28000 ? 261 TYR A CD1   1 
ATOM   1865 C  CD2   . TYR A 1 261 ? 27.93700  15.88000  29.66600  1.000 285.93000 ? 261 TYR A CD2   1 
ATOM   1866 C  CE1   . TYR A 1 261 ? 29.72500  14.25300  30.99400  1.000 290.22000 ? 261 TYR A CE1   1 
ATOM   1867 C  CE2   . TYR A 1 261 ? 27.60900  14.58100  29.92900  1.000 294.75000 ? 261 TYR A CE2   1 
ATOM   1868 C  CZ    . TYR A 1 261 ? 28.50500  13.76800  30.59600  1.000 297.60000 ? 261 TYR A CZ    1 
ATOM   1869 O  OH    . TYR A 1 261 ? 28.16100  12.46200  30.86000  1.000 303.67000 ? 261 TYR A OH    1 
ATOM   1870 N  N     . TYR A 1 262 ? 30.77500  18.92500  32.36900  1.000 285.26000 ? 262 TYR A N     1 
ATOM   1871 C  CA    . TYR A 1 262 ? 31.49300  18.57800  33.59200  1.000 285.96000 ? 262 TYR A CA    1 
ATOM   1872 C  C     . TYR A 1 262 ? 30.85800  19.21300  34.80300  1.000 281.41000 ? 262 TYR A C     1 
ATOM   1873 O  O     . TYR A 1 262 ? 30.70300  18.55800  35.84800  1.000 283.52000 ? 262 TYR A O     1 
ATOM   1874 C  CB    . TYR A 1 262 ? 32.94200  19.00300  33.51100  1.000 287.82000 ? 262 TYR A CB    1 
ATOM   1875 C  CG    . TYR A 1 262 ? 33.66100  18.97900  34.83100  1.000 280.42000 ? 262 TYR A CG    1 
ATOM   1876 C  CD1   . TYR A 1 262 ? 34.44000  20.04800  35.22100  1.000 279.54000 ? 262 TYR A CD1   1 
ATOM   1877 C  CD2   . TYR A 1 262 ? 33.58600  17.87800  35.67600  1.000 277.90000 ? 262 TYR A CD2   1 
ATOM   1878 C  CE1   . TYR A 1 262 ? 35.12000  20.03000  36.40200  1.000 281.08000 ? 262 TYR A CE1   1 
ATOM   1879 C  CE2   . TYR A 1 262 ? 34.26200  17.85600  36.88400  1.000 279.67000 ? 262 TYR A CE2   1 
ATOM   1880 C  CZ    . TYR A 1 262 ? 35.03100  18.93900  37.23000  1.000 280.65000 ? 262 TYR A CZ    1 
ATOM   1881 O  OH    . TYR A 1 262 ? 35.71800  18.95000  38.41000  1.000 293.24000 ? 262 TYR A OH    1 
ATOM   1882 N  N     . LYS A 1 263 ? 30.52500  20.49700  34.69200  1.000 280.71000 ? 263 LYS A N     1 
ATOM   1883 C  CA    . LYS A 1 263 ? 29.78600  21.13300  35.76100  1.000 285.74000 ? 263 LYS A CA    1 
ATOM   1884 C  C     . LYS A 1 263 ? 28.50500  20.37700  36.06600  1.000 289.07000 ? 263 LYS A C     1 
ATOM   1885 O  O     . LYS A 1 263 ? 28.23200  20.07100  37.23200  1.000 291.83000 ? 263 LYS A O     1 
ATOM   1886 C  CB    . LYS A 1 263 ? 29.52000  22.57400  35.37500  1.000 289.63000 ? 263 LYS A CB    1 
ATOM   1887 C  CG    . LYS A 1 263 ? 30.79300  23.40500  35.47600  1.000 291.55000 ? 263 LYS A CG    1 
ATOM   1888 C  CD    . LYS A 1 263 ? 30.69900  24.65900  34.66500  1.000 292.93000 ? 263 LYS A CD    1 
ATOM   1889 C  CE    . LYS A 1 263 ? 32.04000  25.37200  34.59000  1.000 288.37000 ? 263 LYS A CE    1 
ATOM   1890 N  NZ    . LYS A 1 263 ? 32.24900  26.31700  35.72200  1.000 293.88000 ? 263 LYS A NZ    1 
ATOM   1891 N  N     . ALA A 1 264 ? 27.75400  19.98500  35.03700  1.000 285.98000 ? 264 ALA A N     1 
ATOM   1892 C  CA    . ALA A 1 264 ? 26.47800  19.35200  35.32500  1.000 293.14000 ? 264 ALA A CA    1 
ATOM   1893 C  C     . ALA A 1 264 ? 26.61500  18.03900  36.08500  1.000 294.17000 ? 264 ALA A C     1 
ATOM   1894 O  O     . ALA A 1 264 ? 25.59100  17.51300  36.55800  1.000 299.03000 ? 264 ALA A O     1 
ATOM   1895 C  CB    . ALA A 1 264 ? 25.70400  19.12300  34.05000  1.000 293.31000 ? 264 ALA A CB    1 
ATOM   1896 N  N     . GLY A 1 265 ? 27.83600  17.49100  36.20100  1.000 285.25000 ? 265 GLY A N     1 
ATOM   1897 C  CA    . GLY A 1 265 ? 28.07700  16.36400  37.10000  1.000 280.65000 ? 265 GLY A CA    1 
ATOM   1898 C  C     . GLY A 1 265 ? 29.20800  15.43600  36.66900  1.000 275.74000 ? 265 GLY A C     1 
ATOM   1899 O  O     . GLY A 1 265 ? 30.32400  15.46200  37.23200  1.000 282.94000 ? 265 GLY A O     1 
ATOM   1900 N  N     . GLY A 1 266 ? 28.91500  14.58500  35.67600  1.000 278.30000 ? 266 GLY A N     1 
ATOM   1901 C  CA    . GLY A 1 266 ? 29.88600  13.60100  35.24700  1.000 278.00000 ? 266 GLY A CA    1 
ATOM   1902 C  C     . GLY A 1 266 ? 31.05600  14.25600  34.54200  1.000 278.74000 ? 266 GLY A C     1 
ATOM   1903 O  O     . GLY A 1 266 ? 30.97700  15.37300  34.02100  1.000 282.48000 ? 266 GLY A O     1 
ATOM   1904 N  N     . LYS A 1 267 ? 32.14900  13.53900  34.55700  1.000 278.05000 ? 267 LYS A N     1 
ATOM   1905 C  CA    . LYS A 1 267 ? 33.33800  13.92400  33.83300  1.000 282.88000 ? 267 LYS A CA    1 
ATOM   1906 C  C     . LYS A 1 267 ? 33.28400  13.38400  32.40600  1.000 276.34000 ? 267 LYS A C     1 
ATOM   1907 O  O     . LYS A 1 267 ? 32.76000  12.28900  32.17100  1.000 280.99000 ? 267 LYS A O     1 
ATOM   1908 C  CB    . LYS A 1 267 ? 34.50000  13.34200  34.56700  1.000 293.58000 ? 267 LYS A CB    1 
ATOM   1909 C  CG    . LYS A 1 267 ? 34.05500  11.95600  35.12100  1.000 293.81000 ? 267 LYS A CG    1 
ATOM   1910 C  CD    . LYS A 1 267 ? 34.06400  11.93600  36.67900  1.000 288.71000 ? 267 LYS A CD    1 
ATOM   1911 C  CE    . LYS A 1 267 ? 34.81800  10.68600  37.18900  1.000 291.94000 ? 267 LYS A CE    1 
ATOM   1912 N  NZ    . LYS A 1 267 ? 36.13800  10.77700  37.90600  1.000 287.57000 ? 267 LYS A NZ    1 
ATOM   1913 N  N     . PRO A 1 268 ? 33.78000  14.13000  31.42300  1.000 266.08000 ? 268 PRO A N     1 
ATOM   1914 C  CA    . PRO A 1 268 ? 33.80200  13.56500  30.06400  1.000 267.44000 ? 268 PRO A CA    1 
ATOM   1915 C  C     . PRO A 1 268 ? 34.71100  12.36000  29.89600  1.000 265.92000 ? 268 PRO A C     1 
ATOM   1916 O  O     . PRO A 1 268 ? 34.37100  11.44200  29.14300  1.000 267.34000 ? 268 PRO A O     1 
ATOM   1917 C  CB    . PRO A 1 268 ? 34.26000  14.73200  29.18900  1.000 267.85000 ? 268 PRO A CB    1 
ATOM   1918 C  CG    . PRO A 1 268 ? 34.11300  15.92600  30.01000  1.000 269.28000 ? 268 PRO A CG    1 
ATOM   1919 C  CD    . PRO A 1 268 ? 34.05200  15.57700  31.45000  1.000 269.95000 ? 268 PRO A CD    1 
ATOM   1920 N  N     . TRP A 1 269 ? 35.85000  12.30500  30.57300  1.000 270.11000 ? 269 TRP A N     1 
ATOM   1921 C  CA    . TRP A 1 269 ? 36.75800  11.18800  30.31600  1.000 271.90000 ? 269 TRP A CA    1 
ATOM   1922 C  C     . TRP A 1 269 ? 37.68100  10.94900  31.51300  1.000 272.49000 ? 269 TRP A C     1 
ATOM   1923 O  O     . TRP A 1 269 ? 37.68800  11.71900  32.47300  1.000 273.24000 ? 269 TRP A O     1 
ATOM   1924 C  CB    . TRP A 1 269 ? 37.55700  11.44400  29.04700  1.000 270.25000 ? 269 TRP A CB    1 
ATOM   1925 C  CG    . TRP A 1 269 ? 38.40700  12.61600  29.20100  1.000 277.02000 ? 269 TRP A CG    1 
ATOM   1926 C  CD1   . TRP A 1 269 ? 39.60500  12.64900  29.82300  1.000 285.77000 ? 269 TRP A CD1   1 
ATOM   1927 C  CD2   . TRP A 1 269 ? 38.13900  13.95700  28.77500  1.000 275.28000 ? 269 TRP A CD2   1 
ATOM   1928 N  NE1   . TRP A 1 269 ? 40.11800  13.91500  29.81100  1.000 288.81000 ? 269 TRP A NE1   1 
ATOM   1929 C  CE2   . TRP A 1 269 ? 39.24400  14.74100  29.16300  1.000 284.06000 ? 269 TRP A CE2   1 
ATOM   1930 C  CE3   . TRP A 1 269 ? 37.10400  14.56000  28.07500  1.000 270.22000 ? 269 TRP A CE3   1 
ATOM   1931 C  CZ2   . TRP A 1 269 ? 39.33300  16.10800  28.90100  1.000 283.74000 ? 269 TRP A CZ2   1 
ATOM   1932 C  CZ3   . TRP A 1 269 ? 37.17700  15.92700  27.82500  1.000 275.88000 ? 269 TRP A CZ3   1 
ATOM   1933 C  CH2   . TRP A 1 269 ? 38.29500  16.68600  28.23200  1.000 281.43000 ? 269 TRP A CH2   1 
ATOM   1934 N  N     . LYS A 1 270 ? 38.44800  9.85000   31.45600  1.000 271.56000 ? 270 LYS A N     1 
ATOM   1935 C  CA    . LYS A 1 270 ? 39.50000  9.56800   32.43700  1.000 267.16000 ? 270 LYS A CA    1 
ATOM   1936 C  C     . LYS A 1 270 ? 40.81500  9.27400   31.74100  1.000 278.35000 ? 270 LYS A C     1 
ATOM   1937 O  O     . LYS A 1 270 ? 40.82800  8.92200   30.55900  1.000 283.58000 ? 270 LYS A O     1 
ATOM   1938 C  CB    . LYS A 1 270 ? 39.20100  8.35800   33.30400  1.000 267.95000 ? 270 LYS A CB    1 
ATOM   1939 C  CG    . LYS A 1 270 ? 38.62300  8.66600   34.64200  1.000 271.45000 ? 270 LYS A CG    1 
ATOM   1940 C  CD    . LYS A 1 270 ? 38.11600  7.37900   35.20000  1.000 273.70000 ? 270 LYS A CD    1 
ATOM   1941 C  CE    . LYS A 1 270 ? 37.96600  7.44700   36.70200  1.000 285.62000 ? 270 LYS A CE    1 
ATOM   1942 N  NZ    . LYS A 1 270 ? 36.61600  7.93100   37.11800  1.000 281.05000 ? 270 LYS A NZ    1 
ATOM   1943 N  N     . LEU A 1 271 ? 41.92300  9.39400   32.49600  1.000 280.92000 ? 271 LEU A N     1 
ATOM   1944 C  CA    . LEU A 1 271 ? 43.21400  8.98400   31.95900  1.000 280.30000 ? 271 LEU A CA    1 
ATOM   1945 C  C     . LEU A 1 271 ? 43.18300  7.48300   31.71000  1.000 280.10000 ? 271 LEU A C     1 
ATOM   1946 O  O     . LEU A 1 271 ? 42.76800  6.70200   32.57600  1.000 284.24000 ? 271 LEU A O     1 
ATOM   1947 C  CB    . LEU A 1 271 ? 44.35800  9.36600   32.90400  1.000 281.88000 ? 271 LEU A CB    1 
ATOM   1948 C  CG    . LEU A 1 271 ? 45.08800  10.69900  32.67800  1.000 271.69000 ? 271 LEU A CG    1 
ATOM   1949 C  CD1   . LEU A 1 271 ? 46.30300  10.94100  33.56500  1.000 271.98000 ? 271 LEU A CD1   1 
ATOM   1950 C  CD2   . LEU A 1 271 ? 45.49800  10.88900  31.22600  1.000 272.61000 ? 271 LEU A CD2   1 
ATOM   1951 N  N     . GLY A 1 272 ? 43.59000  7.07300   30.50900  1.000 277.67000 ? 272 GLY A N     1 
ATOM   1952 C  CA    . GLY A 1 272 ? 43.35200  5.68900   30.12400  1.000 279.54000 ? 272 GLY A CA    1 
ATOM   1953 C  C     . GLY A 1 272 ? 44.21800  4.71900   30.91800  1.000 285.97000 ? 272 GLY A C     1 
ATOM   1954 O  O     . GLY A 1 272 ? 43.71700  3.79200   31.55700  1.000 292.95000 ? 272 GLY A O     1 
ATOM   1955 N  N     . ASP A 1 273 ? 45.53500  4.93800   30.94000  1.000 282.87000 ? 273 ASP A N     1 
ATOM   1956 C  CA    . ASP A 1 273 ? 46.45700  4.00100   31.59500  1.000 298.48000 ? 273 ASP A CA    1 
ATOM   1957 C  C     . ASP A 1 273 ? 47.28400  4.75700   32.65800  1.000 306.19000 ? 273 ASP A C     1 
ATOM   1958 O  O     . ASP A 1 273 ? 48.49300  4.97100   32.48700  1.000 301.16000 ? 273 ASP A O     1 
ATOM   1959 C  CB    . ASP A 1 273 ? 47.34600  3.29800   30.55600  1.000 304.64000 ? 273 ASP A CB    1 
ATOM   1960 C  CG    . ASP A 1 273 ? 46.55500  2.41300   29.59700  1.000 311.42000 ? 273 ASP A CG    1 
ATOM   1961 O  OD1   . ASP A 1 273 ? 47.13000  1.95700   28.58200  1.000 330.36000 ? 273 ASP A OD1   1 
ATOM   1962 O  OD2   . ASP A 1 273 ? 45.36600  2.18900   29.84700  1.000 309.67000 ? 273 ASP A OD2   1 
ATOM   1963 N  N     . ILE A 1 274 ? 46.65300  5.08400   33.79900  1.000 313.14000 ? 274 ILE A N     1 
ATOM   1964 C  CA    . ILE A 1 274 ? 47.33400  5.66500   34.96800  1.000 310.80000 ? 274 ILE A CA    1 
ATOM   1965 C  C     . ILE A 1 274 ? 47.52200  4.55800   36.01200  1.000 305.51000 ? 274 ILE A C     1 
ATOM   1966 O  O     . ILE A 1 274 ? 46.55100  3.88400   36.39900  1.000 297.85000 ? 274 ILE A O     1 
ATOM   1967 C  CB    . ILE A 1 274 ? 46.56500  6.87600   35.55100  1.000 303.35000 ? 274 ILE A CB    1 
ATOM   1968 C  CG1   . ILE A 1 274 ? 47.47200  7.71400   36.48800  1.000 294.07000 ? 274 ILE A CG1   1 
ATOM   1969 C  CG2   . ILE A 1 274 ? 45.29000  6.38700   36.22100  1.000 293.83000 ? 274 ILE A CG2   1 
ATOM   1970 C  CD1   . ILE A 1 274 ? 48.55800  8.50500   35.78400  1.000 291.92000 ? 274 ILE A CD1   1 
ATOM   1971 N  N     . ARG A 1 275 ? 48.77000  4.36500   36.46000  1.000 307.30000 ? 275 ARG A N     1 
ATOM   1972 C  CA    . ARG A 1 275 ? 49.05200  3.35400   37.47500  1.000 298.41000 ? 275 ARG A CA    1 
ATOM   1973 C  C     . ARG A 1 275 ? 48.33000  3.67100   38.78400  1.000 292.58000 ? 275 ARG A C     1 
ATOM   1974 O  O     . ARG A 1 275 ? 48.26300  4.83100   39.19100  1.000 292.14000 ? 275 ARG A O     1 
ATOM   1975 C  CB    . ARG A 1 275 ? 50.55500  3.24700   37.73300  1.000 292.35000 ? 275 ARG A CB    1 
ATOM   1976 C  CG    . ARG A 1 275 ? 51.46100  3.69700   36.59500  1.000 291.28000 ? 275 ARG A CG    1 
ATOM   1977 C  CD    . ARG A 1 275 ? 51.86800  5.14100   36.77000  1.000 301.12000 ? 275 ARG A CD    1 
ATOM   1978 N  NE    . ARG A 1 275 ? 52.55300  5.31600   38.04900  1.000 303.69000 ? 275 ARG A NE    1 
ATOM   1979 C  CZ    . ARG A 1 275 ? 53.16700  6.43300   38.43100  1.000 304.89000 ? 275 ARG A CZ    1 
ATOM   1980 N  NH1   . ARG A 1 275 ? 53.19400  7.49300   37.63400  1.000 309.44000 ? 275 ARG A NH1   1 
ATOM   1981 N  NH2   . ARG A 1 275 ? 53.75600  6.48600   39.61100  1.000 303.92000 ? 275 ARG A NH2   1 
ATOM   1982 N  N     . PRO A 1 276 ? 47.80300  2.66700   39.47300  1.000 281.70000 ? 276 PRO A N     1 
ATOM   1983 C  CA    . PRO A 1 276 ? 46.92200  2.94000   40.61000  1.000 274.90000 ? 276 PRO A CA    1 
ATOM   1984 C  C     . PRO A 1 276 ? 47.64100  3.69100   41.72400  1.000 269.66000 ? 276 PRO A C     1 
ATOM   1985 O  O     . PRO A 1 276 ? 48.84800  3.54700   41.92200  1.000 264.38000 ? 276 PRO A O     1 
ATOM   1986 C  CB    . PRO A 1 276 ? 46.49500  1.53700   41.05900  1.000 276.87000 ? 276 PRO A CB    1 
ATOM   1987 C  CG    . PRO A 1 276 ? 47.63700  0.66600   40.60300  1.000 272.62000 ? 276 PRO A CG    1 
ATOM   1988 C  CD    . PRO A 1 276 ? 48.00700  1.22700   39.27800  1.000 278.06000 ? 276 PRO A CD    1 
ATOM   1989 N  N     . GLY A 1 277 ? 46.88500  4.51600   42.44200  1.000 272.84000 ? 277 GLY A N     1 
ATOM   1990 C  CA    . GLY A 1 277 ? 47.40500  5.16100   43.63200  1.000 278.74000 ? 277 GLY A CA    1 
ATOM   1991 C  C     . GLY A 1 277 ? 48.47400  6.21900   43.44000  1.000 279.61000 ? 277 GLY A C     1 
ATOM   1992 O  O     . GLY A 1 277 ? 49.42100  6.28100   44.23300  1.000 283.05000 ? 277 GLY A O     1 
ATOM   1993 N  N     . VAL A 1 278 ? 48.35900  7.06000   42.42000  1.000 290.15000 ? 278 VAL A N     1 
ATOM   1994 C  CA    . VAL A 1 278 ? 49.17700  8.26000   42.32400  1.000 291.82000 ? 278 VAL A CA    1 
ATOM   1995 C  C     . VAL A 1 278 ? 48.38500  9.45300   42.85800  1.000 297.11000 ? 278 VAL A C     1 
ATOM   1996 O  O     . VAL A 1 278 ? 47.15300  9.47500   42.81200  1.000 297.31000 ? 278 VAL A O     1 
ATOM   1997 C  CB    . VAL A 1 278 ? 49.64100  8.52100   40.88300  1.000 287.19000 ? 278 VAL A CB    1 
ATOM   1998 C  CG1   . VAL A 1 278 ? 50.85500  9.36400   40.94700  1.000 285.76000 ? 278 VAL A CG1   1 
ATOM   1999 C  CG2   . VAL A 1 278 ? 49.93100  7.21900   40.17100  1.000 285.00000 ? 278 VAL A CG2   1 
ATOM   2000 N  N     . CYS A 1 279 ? 49.09200  10.47000  43.37600  1.000 287.33000 ? 279 CYS A N     1 
ATOM   2001 C  CA    . CYS A 1 279 ? 48.45100  11.69800  43.85500  1.000 285.56000 ? 279 CYS A CA    1 
ATOM   2002 C  C     . CYS A 1 279 ? 49.13500  12.92500  43.27800  1.000 284.81000 ? 279 CYS A C     1 
ATOM   2003 O  O     . CYS A 1 279 ? 50.29000  13.21600  43.60800  1.000 284.91000 ? 279 CYS A O     1 
ATOM   2004 C  CB    . CYS A 1 279 ? 48.45200  11.80200  45.37900  1.000 286.61000 ? 279 CYS A CB    1 
ATOM   2005 S  SG    . CYS A 1 279 ? 47.50000  13.25500  45.91200  1.000 301.27000 ? 279 CYS A SG    1 
ATOM   2006 N  N     . TYR A 1 280 ? 48.41300  13.67200  42.46600  1.000 282.23000 ? 280 TYR A N     1 
ATOM   2007 C  CA    . TYR A 1 280 ? 48.97900  14.86100  41.86600  1.000 281.10000 ? 280 TYR A CA    1 
ATOM   2008 C  C     . TYR A 1 280 ? 48.47100  16.08400  42.61300  1.000 277.43000 ? 280 TYR A C     1 
ATOM   2009 O  O     . TYR A 1 280 ? 47.26700  16.23100  42.84700  1.000 277.75000 ? 280 TYR A O     1 
ATOM   2010 C  CB    . TYR A 1 280 ? 48.67100  14.88300  40.36900  1.000 276.55000 ? 280 TYR A CB    1 
ATOM   2011 C  CG    . TYR A 1 280 ? 49.31200  13.65800  39.70600  1.000 276.98000 ? 280 TYR A CG    1 
ATOM   2012 C  CD1   . TYR A 1 280 ? 50.69000  13.61700  39.44600  1.000 281.39000 ? 280 TYR A CD1   1 
ATOM   2013 C  CD2   . TYR A 1 280 ? 48.56200  12.51500  39.40800  1.000 271.98000 ? 280 TYR A CD2   1 
ATOM   2014 C  CE1   . TYR A 1 280 ? 51.28700  12.49500  38.87200  1.000 280.65000 ? 280 TYR A CE1   1 
ATOM   2015 C  CE2   . TYR A 1 280 ? 49.15300  11.39800  38.83000  1.000 272.10000 ? 280 TYR A CE2   1 
ATOM   2016 C  CZ    . TYR A 1 280 ? 50.50800  11.39900  38.56300  1.000 277.95000 ? 280 TYR A CZ    1 
ATOM   2017 O  OH    . TYR A 1 280 ? 51.08700  10.28600  38.00100  1.000 282.05000 ? 280 TYR A OH    1 
ATOM   2018 N  N     . LEU A 1 281 ? 49.41500  16.90700  43.04800  1.000 268.88000 ? 281 LEU A N     1 
ATOM   2019 C  CA    . LEU A 1 281 ? 49.17600  18.05000  43.90500  1.000 266.48000 ? 281 LEU A CA    1 
ATOM   2020 C  C     . LEU A 1 281 ? 49.73500  19.27300  43.23300  1.000 268.62000 ? 281 LEU A C     1 
ATOM   2021 O  O     . LEU A 1 281 ? 50.95700  19.39500  43.08000  1.000 266.28000 ? 281 LEU A O     1 
ATOM   2022 C  CB    . LEU A 1 281 ? 49.84500  17.90600  45.24000  1.000 270.47000 ? 281 LEU A CB    1 
ATOM   2023 C  CG    . LEU A 1 281 ? 48.83600  17.52300  46.28800  1.000 274.77000 ? 281 LEU A CG    1 
ATOM   2024 C  CD1   . LEU A 1 281 ? 47.43700  17.69900  45.75700  1.000 279.19000 ? 281 LEU A CD1   1 
ATOM   2025 C  CD2   . LEU A 1 281 ? 49.06500  16.10300  46.70500  1.000 284.76000 ? 281 LEU A CD2   1 
ATOM   2026 N  N     . GLY A 1 282 ? 48.84700  20.16900  42.84200  1.000 272.40000 ? 282 GLY A N     1 
ATOM   2027 C  CA    . GLY A 1 282 ? 49.32100  21.32000  42.11900  1.000 271.67000 ? 282 GLY A CA    1 
ATOM   2028 C  C     . GLY A 1 282 ? 49.39200  22.49500  43.05600  1.000 275.85000 ? 282 GLY A C     1 
ATOM   2029 O  O     . GLY A 1 282 ? 48.39000  22.84800  43.68100  1.000 279.63000 ? 282 GLY A O     1 
ATOM   2030 N  N     . LEU A 1 283 ? 50.55700  23.10400  43.19700  1.000 277.53000 ? 283 LEU A N     1 
ATOM   2031 C  CA    . LEU A 1 283 ? 50.72800  24.12600  44.22200  1.000 276.47000 ? 283 LEU A CA    1 
ATOM   2032 C  C     . LEU A 1 283 ? 50.35800  25.49200  43.65500  1.000 274.91000 ? 283 LEU A C     1 
ATOM   2033 O  O     . LEU A 1 283 ? 50.93100  25.92400  42.65400  1.000 274.55000 ? 283 LEU A O     1 
ATOM   2034 C  CB    . LEU A 1 283 ? 52.15700  24.11600  44.77000  1.000 284.26000 ? 283 LEU A CB    1 
ATOM   2035 C  CG    . LEU A 1 283 ? 52.39700  23.00300  45.79400  1.000 285.29000 ? 283 LEU A CG    1 
ATOM   2036 C  CD1   . LEU A 1 283 ? 53.69200  23.19900  46.60100  1.000 284.03000 ? 283 LEU A CD1   1 
ATOM   2037 C  CD2   . LEU A 1 283 ? 51.20300  22.85300  46.73300  1.000 288.70000 ? 283 LEU A CD2   1 
ATOM   2038 N  N     . VAL A 1 284 ? 49.40600  26.17300  44.28400  1.000 287.32000 ? 284 VAL A N     1 
ATOM   2039 C  CA    . VAL A 1 284 ? 48.96400  27.47400  43.80500  1.000 293.75000 ? 284 VAL A CA    1 
ATOM   2040 C  C     . VAL A 1 284 ? 49.15700  28.50000  44.90400  1.000 303.42000 ? 284 VAL A C     1 
ATOM   2041 O  O     . VAL A 1 284 ? 48.89300  28.21200  46.07700  1.000 306.95000 ? 284 VAL A O     1 
ATOM   2042 C  CB    . VAL A 1 284 ? 47.48500  27.47000  43.36500  1.000 297.60000 ? 284 VAL A CB    1 
ATOM   2043 C  CG1   . VAL A 1 284 ? 47.04000  28.90800  43.02700  1.000 304.70000 ? 284 VAL A CG1   1 
ATOM   2044 C  CG2   . VAL A 1 284 ? 47.17600  26.42000  42.24000  1.000 301.36000 ? 284 VAL A CG2   1 
ATOM   2045 N  N     . TYR A 1 285 ? 49.63300  29.68600  44.51700  1.000 307.67000 ? 285 TYR A N     1 
ATOM   2046 C  CA    . TYR A 1 285 ? 49.62900  30.85700  45.37600  1.000 315.49000 ? 285 TYR A CA    1 
ATOM   2047 C  C     . TYR A 1 285 ? 49.23200  32.07000  44.55000  1.000 314.48000 ? 285 TYR A C     1 
ATOM   2048 O  O     . TYR A 1 285 ? 49.26200  32.03900  43.31600  1.000 309.68000 ? 285 TYR A O     1 
ATOM   2049 C  CB    . TYR A 1 285 ? 50.99300  31.11600  46.03100  1.000 319.60000 ? 285 TYR A CB    1 
ATOM   2050 C  CG    . TYR A 1 285 ? 51.71000  29.90200  46.58700  1.000 316.79000 ? 285 TYR A CG    1 
ATOM   2051 C  CD1   . TYR A 1 285 ? 51.72100  29.64200  47.96100  1.000 310.51000 ? 285 TYR A CD1   1 
ATOM   2052 C  CD2   . TYR A 1 285 ? 52.38600  29.02000  45.74100  1.000 315.51000 ? 285 TYR A CD2   1 
ATOM   2053 C  CE1   . TYR A 1 285 ? 52.37600  28.54200  48.47600  1.000 304.11000 ? 285 TYR A CE1   1 
ATOM   2054 C  CE2   . TYR A 1 285 ? 53.04600  27.90800  46.25000  1.000 308.07000 ? 285 TYR A CE2   1 
ATOM   2055 C  CZ    . TYR A 1 285 ? 53.03900  27.67600  47.62000  1.000 300.64000 ? 285 TYR A CZ    1 
ATOM   2056 O  OH    . TYR A 1 285 ? 53.68800  26.58100  48.15400  1.000 290.67000 ? 285 TYR A OH    1 
ATOM   2057 N  N     . LYS A 1 286 ? 48.82700  33.12800  45.26200  1.000 316.08000 ? 286 LYS A N     1 
ATOM   2058 C  CA    . LYS A 1 286 ? 48.55300  34.43700  44.69000  1.000 321.28000 ? 286 LYS A CA    1 
ATOM   2059 C  C     . LYS A 1 286 ? 48.85300  35.47600  45.75200  1.000 321.97000 ? 286 LYS A C     1 
ATOM   2060 O  O     . LYS A 1 286 ? 48.25800  35.45300  46.83800  1.000 320.47000 ? 286 LYS A O     1 
ATOM   2061 C  CB    . LYS A 1 286 ? 47.09600  34.55300  44.17900  1.000 320.03000 ? 286 LYS A CB    1 
ATOM   2062 C  CG    . LYS A 1 286 ? 46.85300  35.67300  43.13400  1.000 319.67000 ? 286 LYS A CG    1 
ATOM   2063 C  CD    . LYS A 1 286 ? 46.93600  35.16600  41.69000  1.000 319.12000 ? 286 LYS A CD    1 
ATOM   2064 C  CE    . LYS A 1 286 ? 47.91400  35.97400  40.85700  1.000 330.62000 ? 286 LYS A CE    1 
ATOM   2065 N  NZ    . LYS A 1 286 ? 49.04400  35.11800  40.38400  1.000 346.13000 ? 286 LYS A NZ    1 
ATOM   2066 N  N     . LYS A 1 287 ? 49.82600  36.33700  45.43600  1.000 324.59000 ? 287 LYS A N     1 
ATOM   2067 C  CA    . LYS A 1 287 ? 50.11500  37.49200  46.26500  1.000 326.86000 ? 287 LYS A CA    1 
ATOM   2068 C  C     . LYS A 1 287 ? 48.84500  38.29300  46.46200  1.000 324.32000 ? 287 LYS A C     1 
ATOM   2069 O  O     . LYS A 1 287 ? 48.08400  38.55000  45.51100  1.000 324.37000 ? 287 LYS A O     1 
ATOM   2070 C  CB    . LYS A 1 287 ? 51.18600  38.37900  45.62500  1.000 332.50000 ? 287 LYS A CB    1 
ATOM   2071 C  CG    . LYS A 1 287 ? 51.63600  39.54200  46.51600  1.000 325.46000 ? 287 LYS A CG    1 
ATOM   2072 C  CD    . LYS A 1 287 ? 52.35100  40.61500  45.71200  1.000 332.27000 ? 287 LYS A CD    1 
ATOM   2073 C  CE    . LYS A 1 287 ? 52.38800  41.92500  46.49100  1.000 325.52000 ? 287 LYS A CE    1 
ATOM   2074 N  NZ    . LYS A 1 287 ? 53.20100  43.02000  45.89500  1.000 327.39000 ? 287 LYS A NZ    1 
ATOM   2075 N  N     . ILE A 1 288 ? 48.59500  38.63800  47.71600  1.000 321.82000 ? 288 ILE A N     1 
ATOM   2076 C  CA    . ILE A 1 288 ? 47.60900  39.65500  48.01700  1.000 321.05000 ? 288 ILE A CA    1 
ATOM   2077 C  C     . ILE A 1 288 ? 48.31600  40.98800  48.04800  1.000 333.37000 ? 288 ILE A C     1 
ATOM   2078 O  O     . ILE A 1 288 ? 49.14400  41.24100  48.92200  1.000 336.41000 ? 288 ILE A O     1 
ATOM   2079 C  CB    . ILE A 1 288 ? 46.85900  39.33900  49.31000  1.000 329.10000 ? 288 ILE A CB    1 
ATOM   2080 C  CG1   . ILE A 1 288 ? 46.21500  37.89700  49.18200  1.000 331.02000 ? 288 ILE A CG1   1 
ATOM   2081 C  CG2   . ILE A 1 288 ? 45.81300  40.28000  49.56700  1.000 328.35000 ? 288 ILE A CG2   1 
ATOM   2082 C  CD1   . ILE A 1 288 ? 44.92200  37.68600  49.84300  1.000 333.28000 ? 288 ILE A CD1   1 
ATOM   2083 N  N     . GLU A 1 289 ? 48.04700  41.78500  47.02000  1.000 328.09000 ? 289 GLU A N     1 
ATOM   2084 C  CA    . GLU A 1 289 ? 48.68100  43.07900  46.92000  1.000 326.92000 ? 289 GLU A CA    1 
ATOM   2085 C  C     . GLU A 1 289 ? 48.18400  43.99900  48.01000  1.000 330.13000 ? 289 GLU A C     1 
ATOM   2086 O  O     . GLU A 1 289 ? 48.89700  44.93300  48.40500  1.000 330.46000 ? 289 GLU A O     1 
ATOM   2087 C  CB    . GLU A 1 289 ? 48.38700  43.65900  45.55200  1.000 330.82000 ? 289 GLU A CB    1 
ATOM   2088 C  CG    . GLU A 1 289 ? 48.08100  42.62700  44.45600  1.000 337.89000 ? 289 GLU A CG    1 
ATOM   2089 C  CD    . GLU A 1 289 ? 49.12100  42.60800  43.32400  1.000 340.86000 ? 289 GLU A CD    1 
ATOM   2090 O  OE1   . GLU A 1 289 ? 50.32200  42.85500  43.59900  1.000 342.40000 ? 289 GLU A OE1   1 
ATOM   2091 O  OE2   . GLU A 1 289 ? 48.73500  42.34200  42.15600  1.000 338.46000 ? 289 GLU A OE2   1 
ATOM   2092 N  N     . LYS A 1 290 ? 46.97400  43.71900  48.51500  1.000 325.53000 ? 290 LYS A N     1 
ATOM   2093 C  CA    . LYS A 1 290 ? 46.30100  44.64000  49.42600  1.000 331.19000 ? 290 LYS A CA    1 
ATOM   2094 C  C     . LYS A 1 290 ? 47.11900  44.89700  50.69100  1.000 340.51000 ? 290 LYS A C     1 
ATOM   2095 O  O     . LYS A 1 290 ? 47.21700  46.04400  51.15300  1.000 346.88000 ? 290 LYS A O     1 
ATOM   2096 C  CB    . LYS A 1 290 ? 44.91400  44.10600  49.78900  1.000 330.80000 ? 290 LYS A CB    1 
ATOM   2097 C  CG    . LYS A 1 290 ? 43.88600  44.10000  48.64500  1.000 329.15000 ? 290 LYS A CG    1 
ATOM   2098 C  CD    . LYS A 1 290 ? 42.45300  44.47400  49.09100  1.000 325.49000 ? 290 LYS A CD    1 
ATOM   2099 C  CE    . LYS A 1 290 ? 42.02400  43.81100  50.38000  1.000 330.71000 ? 290 LYS A CE    1 
ATOM   2100 N  NZ    . LYS A 1 290 ? 42.01600  42.33200  50.24500  1.000 334.76000 ? 290 LYS A NZ    1 
ATOM   2101 N  N     . SER A 1 291 ? 47.73300  43.85200  51.25400  1.000 352.63000 ? 291 SER A N     1 
ATOM   2102 C  CA    . SER A 1 291 ? 48.38300  43.98700  52.55500  1.000 355.95000 ? 291 SER A CA    1 
ATOM   2103 C  C     . SER A 1 291 ? 49.54600  44.97000  52.50400  1.000 355.06000 ? 291 SER A C     1 
ATOM   2104 O  O     . SER A 1 291 ? 50.21000  45.13200  51.46600  1.000 354.42000 ? 291 SER A O     1 
ATOM   2105 C  CB    . SER A 1 291 ? 48.86100  42.62000  53.07400  1.000 351.14000 ? 291 SER A CB    1 
ATOM   2106 O  OG    . SER A 1 291 ? 49.54100  42.74400  54.32200  1.000 335.79000 ? 291 SER A OG    1 
ATOM   2107 N  N     . LYS A 1 292 ? 49.75900  45.64900  53.64200  1.000 354.87000 ? 292 LYS A N     1 
ATOM   2108 C  CA    . LYS A 1 292 ? 50.85700  46.60400  53.72100  1.000 353.80000 ? 292 LYS A CA    1 
ATOM   2109 C  C     . LYS A 1 292 ? 52.20100  45.88300  53.65700  1.000 349.81000 ? 292 LYS A C     1 
ATOM   2110 O  O     . LYS A 1 292 ? 53.13000  46.33200  52.97700  1.000 353.88000 ? 292 LYS A O     1 
ATOM   2111 C  CB    . LYS A 1 292 ? 50.70600  47.46000  54.99300  1.000 351.62000 ? 292 LYS A CB    1 
ATOM   2112 C  CG    . LYS A 1 292 ? 49.41600  48.30500  55.03500  1.000 350.57000 ? 292 LYS A CG    1 
ATOM   2113 C  CD    . LYS A 1 292 ? 49.40500  49.32200  56.17100  1.000 340.78000 ? 292 LYS A CD    1 
ATOM   2114 C  CE    . LYS A 1 292 ? 49.11700  48.63500  57.48100  1.000 341.76000 ? 292 LYS A CE    1 
ATOM   2115 N  NZ    . LYS A 1 292 ? 50.07500  49.03800  58.53600  1.000 325.02000 ? 292 LYS A NZ    1 
ATOM   2116 N  N     . ASN A 1 293 ? 52.27400  44.71000  54.27300  1.000 341.33000 ? 293 ASN A N     1 
ATOM   2117 C  CA    . ASN A 1 293 ? 53.42200  43.82400  54.24100  1.000 341.39000 ? 293 ASN A CA    1 
ATOM   2118 C  C     . ASN A 1 293 ? 53.28100  42.96500  52.95400  1.000 345.23000 ? 293 ASN A C     1 
ATOM   2119 O  O     . ASN A 1 293 ? 52.35900  42.13500  52.90500  1.000 349.67000 ? 293 ASN A O     1 
ATOM   2120 C  CB    . ASN A 1 293 ? 53.45000  43.01000  55.54600  1.000 332.43000 ? 293 ASN A CB    1 
ATOM   2121 C  CG    . ASN A 1 293 ? 54.12500  41.64700  55.47000  1.000 325.02000 ? 293 ASN A CG    1 
ATOM   2122 O  OD1   . ASN A 1 293 ? 53.69600  40.77600  54.72200  1.000 335.35000 ? 293 ASN A OD1   1 
ATOM   2123 N  ND2   . ASN A 1 293 ? 55.10700  41.42400  56.31600  1.000 328.67000 ? 293 ASN A ND2   1 
ATOM   2124 N  N     . PRO A 1 294 ? 54.17000  43.17100  51.88400  1.000 347.34000 ? 294 PRO A N     1 
ATOM   2125 C  CA    . PRO A 1 294 ? 53.93000  42.57000  50.52600  1.000 337.61000 ? 294 PRO A CA    1 
ATOM   2126 C  C     . PRO A 1 294 ? 54.37800  41.12200  50.37300  1.000 340.91000 ? 294 PRO A C     1 
ATOM   2127 O  O     . PRO A 1 294 ? 55.13300  40.74500  49.44500  1.000 331.67000 ? 294 PRO A O     1 
ATOM   2128 C  CB    . PRO A 1 294 ? 54.72500  43.52200  49.61100  1.000 328.01000 ? 294 PRO A CB    1 
ATOM   2129 C  CG    . PRO A 1 294 ? 55.52900  44.40700  50.46500  1.000 330.90000 ? 294 PRO A CG    1 
ATOM   2130 C  CD    . PRO A 1 294 ? 55.36700  44.00600  51.91600  1.000 340.49000 ? 294 PRO A CD    1 
ATOM   2131 N  N     . GLN A 1 295 ? 53.90600  40.26700  51.31600  1.000 353.10000 ? 295 GLN A N     1 
ATOM   2132 C  CA    . GLN A 1 295 ? 54.13300  38.82200  51.42500  1.000 350.14000 ? 295 GLN A CA    1 
ATOM   2133 C  C     . GLN A 1 295 ? 52.82900  38.04200  51.62100  1.000 344.57000 ? 295 GLN A C     1 
ATOM   2134 O  O     . GLN A 1 295 ? 52.82300  36.81900  51.37100  1.000 335.24000 ? 295 GLN A O     1 
ATOM   2135 C  CB    . GLN A 1 295 ? 55.09500  38.48300  52.60000  1.000 358.29000 ? 295 GLN A CB    1 
ATOM   2136 C  CG    . GLN A 1 295 ? 56.61100  38.29700  52.33700  1.000 352.52000 ? 295 GLN A CG    1 
ATOM   2137 C  CD    . GLN A 1 295 ? 57.30700  37.45500  53.45900  1.000 339.81000 ? 295 GLN A CD    1 
ATOM   2138 O  OE1   . GLN A 1 295 ? 57.26800  37.80800  54.65000  1.000 327.04000 ? 295 GLN A OE1   1 
ATOM   2139 N  NE2   . GLN A 1 295 ? 57.96000  36.35100  53.06100  1.000 333.77000 ? 295 GLN A NE2   1 
ATOM   2140 N  N     . ASN A 1 296 ? 51.75300  38.69200  52.11700  1.000 346.70000 ? 296 ASN A N     1 
ATOM   2141 C  CA    . ASN A 1 296 ? 50.42400  38.06400  52.14000  1.000 337.40000 ? 296 ASN A CA    1 
ATOM   2142 C  C     . ASN A 1 296 ? 50.15100  37.56200  50.70900  1.000 329.67000 ? 296 ASN A C     1 
ATOM   2143 O  O     . ASN A 1 296 ? 50.11400  38.27000  49.70400  1.000 325.74000 ? 296 ASN A O     1 
ATOM   2144 C  CB    . ASN A 1 296 ? 49.32400  39.00900  52.61300  1.000 335.89000 ? 296 ASN A CB    1 
ATOM   2145 C  CG    . ASN A 1 296 ? 49.07600  38.97100  54.18800  1.000 327.71000 ? 296 ASN A CG    1 
ATOM   2146 O  OD1   . ASN A 1 296 ? 49.86600  38.36900  54.93900  1.000 321.61000 ? 296 ASN A OD1   1 
ATOM   2147 N  ND2   . ASN A 1 296 ? 48.01300  39.61800  54.65900  1.000 331.72000 ? 296 ASN A ND2   1 
ATOM   2148 N  N     . ALA A 1 297 ? 49.99200  36.26700  50.61600  1.000 328.54000 ? 297 ALA A N     1 
ATOM   2149 C  CA    . ALA A 1 297 ? 49.82300  35.48500  49.39500  1.000 320.57000 ? 297 ALA A CA    1 
ATOM   2150 C  C     . ALA A 1 297 ? 48.93600  34.28700  49.74400  1.000 318.77000 ? 297 ALA A C     1 
ATOM   2151 O  O     . ALA A 1 297 ? 49.23900  33.46800  50.65200  1.000 316.80000 ? 297 ALA A O     1 
ATOM   2152 C  CB    . ALA A 1 297 ? 51.17000  34.97800  48.85600  1.000 316.62000 ? 297 ALA A CB    1 
ATOM   2153 N  N     . CYS A 1 298 ? 47.79400  34.23900  49.08200  1.000 323.73000 ? 298 CYS A N     1 
ATOM   2154 C  CA    . CYS A 1 298 ? 46.91200  33.13900  49.37100  1.000 319.91000 ? 298 CYS A CA    1 
ATOM   2155 C  C     . CYS A 1 298 ? 47.54800  31.87600  48.82800  1.000 313.60000 ? 298 CYS A C     1 
ATOM   2156 O  O     . CYS A 1 298 ? 48.43000  31.92000  47.97000  1.000 311.03000 ? 298 CYS A O     1 
ATOM   2157 C  CB    . CYS A 1 298 ? 45.52500  33.35300  48.77500  1.000 316.05000 ? 298 CYS A CB    1 
ATOM   2158 S  SG    . CYS A 1 298 ? 44.31600  32.46300  49.68300  1.000 324.35000 ? 298 CYS A SG    1 
ATOM   2159 N  N     . CYS A 1 299 ? 47.17800  30.75300  49.41700  1.000 317.26000 ? 299 CYS A N     1 
ATOM   2160 C  CA    . CYS A 1 299 ? 47.77800  29.48400  49.06900  1.000 314.58000 ? 299 CYS A CA    1 
ATOM   2161 C  C     . CYS A 1 299 ? 46.71100  28.42900  48.89300  1.000 310.97000 ? 299 CYS A C     1 
ATOM   2162 O  O     . CYS A 1 299 ? 45.62900  28.49000  49.49400  1.000 311.94000 ? 299 CYS A O     1 
ATOM   2163 C  CB    . CYS A 1 299 ? 48.71300  28.97600  50.10500  1.000 311.13000 ? 299 CYS A CB    1 
ATOM   2164 S  SG    . CYS A 1 299 ? 48.98000  27.23800  49.76400  1.000 306.14000 ? 299 CYS A SG    1 
ATOM   2165 N  N     . ALA A 1 300 ? 47.09400  27.40500  48.14400  1.000 304.85000 ? 300 ALA A N     1 
ATOM   2166 C  CA    . ALA A 1 300 ? 46.20300  26.30600  47.86800  1.000 303.35000 ? 300 ALA A CA    1 
ATOM   2167 C  C     . ALA A 1 300 ? 46.99000  25.11700  47.35700  1.000 296.43000 ? 300 ALA A C     1 
ATOM   2168 O  O     . ALA A 1 300 ? 48.20100  25.16900  47.15300  1.000 293.13000 ? 300 ALA A O     1 
ATOM   2169 C  CB    . ALA A 1 300 ? 45.14000  26.71200  46.85400  1.000 308.50000 ? 300 ALA A CB    1 
ATOM   2170 N  N     . ALA A 1 301 ? 46.26900  24.03700  47.15200  1.000 290.53000 ? 301 ALA A N     1 
ATOM   2171 C  CA    . ALA A 1 301 ? 46.80000  22.87900  46.47300  1.000 286.78000 ? 301 ALA A CA    1 
ATOM   2172 C  C     . ALA A 1 301 ? 45.61900  22.21600  45.82800  1.000 288.56000 ? 301 ALA A C     1 
ATOM   2173 O  O     . ALA A 1 301 ? 44.53500  22.13500  46.41000  1.000 294.37000 ? 301 ALA A O     1 
ATOM   2174 C  CB    . ALA A 1 301 ? 47.48700  21.88200  47.39900  1.000 296.27000 ? 301 ALA A CB    1 
ATOM   2175 N  N     . GLN A 1 302 ? 45.83500  21.74600  44.63400  1.000 289.69000 ? 302 GLN A N     1 
ATOM   2176 C  CA    . GLN A 1 302 ? 44.79000  21.07600  43.91200  1.000 286.49000 ? 302 GLN A CA    1 
ATOM   2177 C  C     . GLN A 1 302 ? 45.24500  19.64600  43.72100  1.000 280.39000 ? 302 GLN A C     1 
ATOM   2178 O  O     . GLN A 1 302 ? 46.42600  19.39500  43.45600  1.000 275.32000 ? 302 GLN A O     1 
ATOM   2179 C  CB    . GLN A 1 302 ? 44.53100  21.80100  42.60400  1.000 291.96000 ? 302 GLN A CB    1 
ATOM   2180 C  CG    . GLN A 1 302 ? 45.80300  22.44500  42.05700  1.000 298.02000 ? 302 GLN A CG    1 
ATOM   2181 C  CD    . GLN A 1 302 ? 45.54200  23.50000  40.98900  1.000 305.98000 ? 302 GLN A CD    1 
ATOM   2182 O  OE1   . GLN A 1 302 ? 44.39400  23.83900  40.71000  1.000 310.32000 ? 302 GLN A OE1   1 
ATOM   2183 N  NE2   . GLN A 1 302 ? 46.62100  24.01000  40.36900  1.000 306.33000 ? 302 GLN A NE2   1 
ATOM   2184 N  N     . MET A 1 303 ? 44.31800  18.72100  43.88300  1.000 285.44000 ? 303 MET A N     1 
ATOM   2185 C  CA    . MET A 1 303 ? 44.63300  17.30700  43.89800  1.000 280.90000 ? 303 MET A CA    1 
ATOM   2186 C  C     . MET A 1 303 ? 44.03600  16.62600  42.68700  1.000 279.75000 ? 303 MET A C     1 
ATOM   2187 O  O     . MET A 1 303 ? 42.81300  16.55100  42.55400  1.000 283.23000 ? 303 MET A O     1 
ATOM   2188 C  CB    . MET A 1 303 ? 44.10100  16.67000  45.16600  1.000 287.79000 ? 303 MET A CB    1 
ATOM   2189 C  CG    . MET A 1 303 ? 44.51800  15.24300  45.32100  1.000 294.93000 ? 303 MET A CG    1 
ATOM   2190 S  SD    . MET A 1 303 ? 43.35100  14.38400  46.37700  1.000 309.20000 ? 303 MET A SD    1 
ATOM   2191 C  CE    . MET A 1 303 ? 41.83900  14.58600  45.45400  1.000 295.16000 ? 303 MET A CE    1 
ATOM   2192 N  N     . PHE A 1 304 ? 44.89300  16.14800  41.80700  1.000 275.24000 ? 304 PHE A N     1 
ATOM   2193 C  CA    . PHE A 1 304 ? 44.43700  15.42300  40.64300  1.000 272.27000 ? 304 PHE A CA    1 
ATOM   2194 C  C     . PHE A 1 304 ? 44.89800  13.99300  40.76300  1.000 271.85000 ? 304 PHE A C     1 
ATOM   2195 O  O     . PHE A 1 304 ? 46.03200  13.72500  41.16700  1.000 273.89000 ? 304 PHE A O     1 
ATOM   2196 C  CB    . PHE A 1 304 ? 44.97400  15.97600  39.36700  1.000 270.46000 ? 304 PHE A CB    1 
ATOM   2197 C  CG    . PHE A 1 304 ? 44.48400  17.32800  39.04900  1.000 273.34000 ? 304 PHE A CG    1 
ATOM   2198 C  CD1   . PHE A 1 304 ? 45.29000  18.41700  39.26400  1.000 276.49000 ? 304 PHE A CD1   1 
ATOM   2199 C  CD2   . PHE A 1 304 ? 43.21700  17.52000  38.54500  1.000 276.45000 ? 304 PHE A CD2   1 
ATOM   2200 C  CE1   . PHE A 1 304 ? 44.84700  19.67100  38.97600  1.000 278.61000 ? 304 PHE A CE1   1 
ATOM   2201 C  CE2   . PHE A 1 304 ? 42.77300  18.77300  38.25200  1.000 278.67000 ? 304 PHE A CE2   1 
ATOM   2202 C  CZ    . PHE A 1 304 ? 43.59600  19.85100  38.46600  1.000 279.37000 ? 304 PHE A CZ    1 
ATOM   2203 N  N     . LEU A 1 305 ? 44.02000  13.08600  40.38400  1.000 269.04000 ? 305 LEU A N     1 
ATOM   2204 C  CA    . LEU A 1 305 ? 44.31100  11.67100  40.48400  1.000 277.05000 ? 305 LEU A CA    1 
ATOM   2205 C  C     . LEU A 1 305 ? 44.55900  11.10300  39.10300  1.000 270.94000 ? 305 LEU A C     1 
ATOM   2206 O  O     . LEU A 1 305 ? 45.69500  11.03700  38.62100  1.000 267.94000 ? 305 LEU A O     1 
ATOM   2207 C  CB    . LEU A 1 305 ? 43.12700  10.97600  41.14500  1.000 287.78000 ? 305 LEU A CB    1 
ATOM   2208 C  CG    . LEU A 1 305 ? 42.96800  11.64100  42.51300  1.000 296.06000 ? 305 LEU A CG    1 
ATOM   2209 C  CD1   . LEU A 1 305 ? 41.60300  11.42300  43.17200  1.000 298.97000 ? 305 LEU A CD1   1 
ATOM   2210 C  CD2   . LEU A 1 305 ? 44.12200  11.23300  43.44500  1.000 297.27000 ? 305 LEU A CD2   1 
ATOM   2211 N  N     . ASP A 1 306 ? 43.46100  10.69400  38.48900  1.000 277.37000 ? 306 ASP A N     1 
ATOM   2212 C  CA    . ASP A 1 306 ? 43.38900  10.20400  37.14100  1.000 280.81000 ? 306 ASP A CA    1 
ATOM   2213 C  C     . ASP A 1 306 ? 42.26100  10.86100  36.36300  1.000 277.11000 ? 306 ASP A C     1 
ATOM   2214 O  O     . ASP A 1 306 ? 42.16600  10.60800  35.17000  1.000 280.67000 ? 306 ASP A O     1 
ATOM   2215 C  CB    . ASP A 1 306 ? 43.14100  8.68700   37.15300  1.000 284.50000 ? 306 ASP A CB    1 
ATOM   2216 C  CG    . ASP A 1 306 ? 41.80400  8.34400   37.76800  1.000 287.95000 ? 306 ASP A CG    1 
ATOM   2217 O  OD1   . ASP A 1 306 ? 41.27000  7.27600   37.42600  1.000 292.70000 ? 306 ASP A OD1   1 
ATOM   2218 O  OD2   . ASP A 1 306 ? 41.28300  9.17000   38.59000  1.000 284.93000 ? 306 ASP A OD2   1 
ATOM   2219 N  N     . ASN A 1 307 ? 41.37000  11.62100  37.00700  1.000 264.36000 ? 307 ASN A N     1 
ATOM   2220 C  CA    . ASN A 1 307 ? 40.21400  12.22600  36.39600  1.000 263.15000 ? 307 ASN A CA    1 
ATOM   2221 C  C     . ASN A 1 307 ? 40.41700  13.66500  35.98900  1.000 267.38000 ? 307 ASN A C     1 
ATOM   2222 O  O     . ASN A 1 307 ? 40.09400  14.03200  34.86400  1.000 270.72000 ? 307 ASN A O     1 
ATOM   2223 C  CB    . ASN A 1 307 ? 39.07900  12.11900  37.36500  1.000 265.07000 ? 307 ASN A CB    1 
ATOM   2224 C  CG    . ASN A 1 307 ? 39.39200  12.57800  38.76200  1.000 277.89000 ? 307 ASN A CG    1 
ATOM   2225 O  OD1   . ASN A 1 307 ? 40.35200  13.25600  38.94100  1.000 273.65000 ? 307 ASN A OD1   1 
ATOM   2226 N  ND2   . ASN A 1 307 ? 38.59200  12.16000  39.77100  1.000 282.95000 ? 307 ASN A ND2   1 
ATOM   2227 N  N     . GLY A 1 308 ? 41.00600  14.48200  36.83900  1.000 280.38000 ? 308 GLY A N     1 
ATOM   2228 C  CA    . GLY A 1 308 ? 40.99200  15.89000  36.54800  1.000 281.81000 ? 308 GLY A CA    1 
ATOM   2229 C  C     . GLY A 1 308 ? 39.74400  16.59800  37.01000  1.000 280.77000 ? 308 GLY A C     1 
ATOM   2230 O  O     . GLY A 1 308 ? 39.67800  17.85100  36.95600  1.000 279.93000 ? 308 GLY A O     1 
ATOM   2231 N  N     . ASP A 1 309 ? 38.74200  15.84100  37.46600  1.000 284.76000 ? 309 ASP A N     1 
ATOM   2232 C  CA    . ASP A 1 309 ? 37.69500  16.50700  38.22900  1.000 290.11000 ? 309 ASP A CA    1 
ATOM   2233 C  C     . ASP A 1 309 ? 38.31200  17.39200  39.29400  1.000 293.04000 ? 309 ASP A C     1 
ATOM   2234 O  O     . ASP A 1 309 ? 37.80800  18.49400  39.57400  1.000 304.34000 ? 309 ASP A O     1 
ATOM   2235 C  CB    . ASP A 1 309 ? 36.72900  15.50800  38.87500  1.000 299.79000 ? 309 ASP A CB    1 
ATOM   2236 C  CG    . ASP A 1 309 ? 35.56100  16.19400  39.62000  1.000 303.10000 ? 309 ASP A CG    1 
ATOM   2237 O  OD1   . ASP A 1 309 ? 35.40400  17.40900  39.62900  1.000 297.12000 ? 309 ASP A OD1   1 
ATOM   2238 O  OD2   . ASP A 1 309 ? 34.77200  15.45500  40.23700  1.000 310.59000 ? 309 ASP A OD2   1 
ATOM   2239 N  N     . GLY A 1 310 ? 39.43400  16.94400  39.85100  1.000 293.21000 ? 310 GLY A N     1 
ATOM   2240 C  CA    . GLY A 1 310 ? 40.19200  17.76900  40.75100  1.000 291.26000 ? 310 GLY A CA    1 
ATOM   2241 C  C     . GLY A 1 310 ? 39.56500  18.01500  42.10300  1.000 294.40000 ? 310 GLY A C     1 
ATOM   2242 O  O     . GLY A 1 310 ? 38.34200  17.94600  42.27400  1.000 297.56000 ? 310 GLY A O     1 
ATOM   2243 N  N     . THR A 1 311 ? 40.42100  18.28100  43.07700  1.000 289.06000 ? 311 THR A N     1 
ATOM   2244 C  CA    . THR A 1 311 ? 40.00300  18.71600  44.39200  1.000 288.20000 ? 311 THR A CA    1 
ATOM   2245 C  C     . THR A 1 311 ? 40.91000  19.87300  44.76700  1.000 289.04000 ? 311 THR A C     1 
ATOM   2246 O  O     . THR A 1 311 ? 42.13400  19.73000  44.76700  1.000 290.29000 ? 311 THR A O     1 
ATOM   2247 C  CB    . THR A 1 311 ? 40.08100  17.57400  45.40500  1.000 291.39000 ? 311 THR A CB    1 
ATOM   2248 O  OG1   . THR A 1 311 ? 39.10800  16.57900  45.06800  1.000 296.54000 ? 311 THR A OG1   1 
ATOM   2249 C  CG2   . THR A 1 311 ? 39.80800  18.06200  46.81900  1.000 298.06000 ? 311 THR A CG2   1 
ATOM   2250 N  N     . VAL A 1 312 ? 40.32100  21.02400  45.05400  1.000 289.48000 ? 312 VAL A N     1 
ATOM   2251 C  CA    . VAL A 1 312 ? 41.08300  22.21600  45.40900  1.000 290.07000 ? 312 VAL A CA    1 
ATOM   2252 C  C     . VAL A 1 312 ? 41.08200  22.34300  46.92600  1.000 294.61000 ? 312 VAL A C     1 
ATOM   2253 O  O     . VAL A 1 312 ? 40.04500  22.65600  47.52400  1.000 292.68000 ? 312 VAL A O     1 
ATOM   2254 C  CB    . VAL A 1 312 ? 40.51100  23.47600  44.75100  1.000 290.08000 ? 312 VAL A CB    1 
ATOM   2255 C  CG1   . VAL A 1 312 ? 41.59600  24.53800  44.67900  1.000 292.63000 ? 312 VAL A CG1   1 
ATOM   2256 C  CG2   . VAL A 1 312 ? 39.99000  23.14700  43.38600  1.000 292.23000 ? 312 VAL A CG2   1 
ATOM   2257 N  N     . PHE A 1 313 ? 42.23500  22.06500  47.54000  1.000 300.39000 ? 313 PHE A N     1 
ATOM   2258 C  CA    . PHE A 1 313 ? 42.43300  22.23300  48.97500  1.000 304.47000 ? 313 PHE A CA    1 
ATOM   2259 C  C     . PHE A 1 313 ? 42.86800  23.66800  49.25200  1.000 305.48000 ? 313 PHE A C     1 
ATOM   2260 O  O     . PHE A 1 313 ? 43.98500  24.06400  48.90200  1.000 305.47000 ? 313 PHE A O     1 
ATOM   2261 C  CB    . PHE A 1 313 ? 43.48900  21.26400  49.50500  1.000 304.99000 ? 313 PHE A CB    1 
ATOM   2262 C  CG    . PHE A 1 313 ? 43.08400  19.82800  49.43900  1.000 300.53000 ? 313 PHE A CG    1 
ATOM   2263 C  CD1   . PHE A 1 313 ? 42.26400  19.28300  50.41200  1.000 299.94000 ? 313 PHE A CD1   1 
ATOM   2264 C  CD2   . PHE A 1 313 ? 43.53800  19.01200  48.41800  1.000 294.94000 ? 313 PHE A CD2   1 
ATOM   2265 C  CE1   . PHE A 1 313 ? 41.88800  17.96700  50.36000  1.000 294.66000 ? 313 PHE A CE1   1 
ATOM   2266 C  CE2   . PHE A 1 313 ? 43.16600  17.68700  48.36600  1.000 293.12000 ? 313 PHE A CE2   1 
ATOM   2267 C  CZ    . PHE A 1 313 ? 42.33500  17.16700  49.34000  1.000 292.45000 ? 313 PHE A CZ    1 
ATOM   2268 N  N     . LYS A 1 314 ? 41.99500  24.44400  49.87900  1.000 298.14000 ? 314 LYS A N     1 
ATOM   2269 C  CA    . LYS A 1 314 ? 42.26500  25.85300  50.13000  1.000 297.92000 ? 314 LYS A CA    1 
ATOM   2270 C  C     . LYS A 1 314 ? 43.12600  25.98000  51.38000  1.000 301.93000 ? 314 LYS A C     1 
ATOM   2271 O  O     . LYS A 1 314 ? 42.69600  25.61300  52.48100  1.000 303.47000 ? 314 LYS A O     1 
ATOM   2272 C  CB    . LYS A 1 314 ? 40.96500  26.63900  50.28800  1.000 294.22000 ? 314 LYS A CB    1 
ATOM   2273 C  CG    . LYS A 1 314 ? 41.17100  28.11600  50.33100  1.000 294.49000 ? 314 LYS A CG    1 
ATOM   2274 C  CD    . LYS A 1 314 ? 39.87100  28.80400  50.61600  1.000 309.03000 ? 314 LYS A CD    1 
ATOM   2275 C  CE    . LYS A 1 314 ? 40.02000  29.70800  51.82100  1.000 330.11000 ? 314 LYS A CE    1 
ATOM   2276 N  NZ    . LYS A 1 314 ? 40.20000  28.98200  53.10600  1.000 326.65000 ? 314 LYS A NZ    1 
ATOM   2277 N  N     . GLY A 1 315 ? 44.34300  26.47700  51.20000  1.000 298.14000 ? 315 GLY A N     1 
ATOM   2278 C  CA    . GLY A 1 315 ? 45.18900  26.82400  52.31700  1.000 299.11000 ? 315 GLY A CA    1 
ATOM   2279 C  C     . GLY A 1 315 ? 44.91800  28.24900  52.74700  1.000 316.08000 ? 315 GLY A C     1 
ATOM   2280 O  O     . GLY A 1 315 ? 44.33000  29.03500  52.01200  1.000 312.22000 ? 315 GLY A O     1 
ATOM   2281 N  N     . GLU A 1 316 ? 45.34300  28.57500  53.95600  1.000 317.30000 ? 316 GLU A N     1 
ATOM   2282 C  CA    . GLU A 1 316 ? 45.04400  29.89900  54.46600  1.000 308.31000 ? 316 GLU A CA    1 
ATOM   2283 C  C     . GLU A 1 316 ? 46.22400  30.84800  54.23600  1.000 301.61000 ? 316 GLU A C     1 
ATOM   2284 O  O     . GLU A 1 316 ? 47.26600  30.47500  53.69600  1.000 290.84000 ? 316 GLU A O     1 
ATOM   2285 C  CB    . GLU A 1 316 ? 44.62900  29.81200  55.93200  1.000 323.04000 ? 316 GLU A CB    1 
ATOM   2286 C  CG    . GLU A 1 316 ? 43.18200  29.34300  56.09700  1.000 328.82000 ? 316 GLU A CG    1 
ATOM   2287 C  CD    . GLU A 1 316 ? 42.18400  30.40800  55.66900  1.000 332.72000 ? 316 GLU A CD    1 
ATOM   2288 O  OE1   . GLU A 1 316 ? 41.84100  30.50800  54.47300  1.000 325.47000 ? 316 GLU A OE1   1 
ATOM   2289 O  OE2   . GLU A 1 316 ? 41.74200  31.16000  56.54700  1.000 333.99000 ? 316 GLU A OE2   1 
ATOM   2290 N  N     . VAL A 1 317 ? 46.03100  32.09700  54.63300  1.000 292.65000 ? 317 VAL A N     1 
ATOM   2291 C  CA    . VAL A 1 317 ? 46.80300  33.21800  54.11300  1.000 285.07000 ? 317 VAL A CA    1 
ATOM   2292 C  C     . VAL A 1 317 ? 48.07900  33.35900  54.91500  1.000 281.67000 ? 317 VAL A C     1 
ATOM   2293 O  O     . VAL A 1 317 ? 48.03200  33.59000  56.12400  1.000 291.01000 ? 317 VAL A O     1 
ATOM   2294 C  CB    . VAL A 1 317 ? 45.99300  34.52000  54.18300  1.000 281.41000 ? 317 VAL A CB    1 
ATOM   2295 C  CG1   . VAL A 1 317 ? 46.56600  35.52600  53.22900  1.000 289.48000 ? 317 VAL A CG1   1 
ATOM   2296 C  CG2   . VAL A 1 317 ? 44.52200  34.26100  53.91200  1.000 282.84000 ? 317 VAL A CG2   1 
ATOM   2297 N  N     . GLY A 1 318 ? 49.21700  33.29800  54.24300  1.000 293.21000 ? 318 GLY A N     1 
ATOM   2298 C  CA    . GLY A 1 318 ? 50.46600  33.40200  54.94700  1.000 292.24000 ? 318 GLY A CA    1 
ATOM   2299 C  C     . GLY A 1 318 ? 51.50400  34.22400  54.23400  1.000 293.57000 ? 318 GLY A C     1 
ATOM   2300 O  O     . GLY A 1 318 ? 51.22300  34.92500  53.25900  1.000 299.14000 ? 318 GLY A O     1 
ATOM   2301 N  N     . PRO A 1 319 ? 52.71800  34.19800  54.75500  1.000 298.98000 ? 319 PRO A N     1 
ATOM   2302 C  CA    . PRO A 1 319 ? 53.82900  34.92900  54.14100  1.000 307.64000 ? 319 PRO A CA    1 
ATOM   2303 C  C     . PRO A 1 319 ? 54.56000  34.03500  53.15200  1.000 306.37000 ? 319 PRO A C     1 
ATOM   2304 O  O     . PRO A 1 319 ? 55.63500  33.48800  53.41800  1.000 302.08000 ? 319 PRO A O     1 
ATOM   2305 C  CB    . PRO A 1 319 ? 54.68100  35.29200  55.35000  1.000 307.73000 ? 319 PRO A CB    1 
ATOM   2306 C  CG    . PRO A 1 319 ? 54.53100  34.08800  56.23200  1.000 308.20000 ? 319 PRO A CG    1 
ATOM   2307 C  CD    . PRO A 1 319 ? 53.11800  33.59300  56.03500  1.000 306.19000 ? 319 PRO A CD    1 
ATOM   2308 N  N     . TRP A 1 320 ? 53.93900  33.86600  51.99800  1.000 309.15000 ? 320 TRP A N     1 
ATOM   2309 C  CA    . TRP A 1 320 ? 54.49400  32.92700  51.04800  1.000 308.57000 ? 320 TRP A CA    1 
ATOM   2310 C  C     . TRP A 1 320 ? 55.32500  33.62600  49.99100  1.000 312.08000 ? 320 TRP A C     1 
ATOM   2311 O  O     . TRP A 1 320 ? 56.39800  33.13300  49.62600  1.000 317.23000 ? 320 TRP A O     1 
ATOM   2312 C  CB    . TRP A 1 320 ? 53.36400  32.12000  50.41300  1.000 308.60000 ? 320 TRP A CB    1 
ATOM   2313 C  CG    . TRP A 1 320 ? 52.35400  31.63600  51.41300  1.000 302.80000 ? 320 TRP A CG    1 
ATOM   2314 C  CD1   . TRP A 1 320 ? 51.01300  31.57100  51.23200  1.000 302.71000 ? 320 TRP A CD1   1 
ATOM   2315 C  CD2   . TRP A 1 320 ? 52.60100  31.15400  52.73800  1.000 301.33000 ? 320 TRP A CD2   1 
ATOM   2316 N  NE1   . TRP A 1 320 ? 50.39800  31.09100  52.35500  1.000 304.92000 ? 320 TRP A NE1   1 
ATOM   2317 C  CE2   . TRP A 1 320 ? 51.35400  30.81500  53.29100  1.000 299.73000 ? 320 TRP A CE2   1 
ATOM   2318 C  CE3   . TRP A 1 320 ? 53.75400  30.96200  53.50400  1.000 301.47000 ? 320 TRP A CE3   1 
ATOM   2319 C  CZ2   . TRP A 1 320 ? 51.22300  30.30400  54.56800  1.000 303.98000 ? 320 TRP A CZ2   1 
ATOM   2320 C  CZ3   . TRP A 1 320 ? 53.62900  30.46200  54.76300  1.000 304.90000 ? 320 TRP A CZ3   1 
ATOM   2321 C  CH2   . TRP A 1 320 ? 52.36900  30.13700  55.29200  1.000 311.09000 ? 320 TRP A CH2   1 
ATOM   2322 N  N     . TYR A 1 321 ? 54.88700  34.79500  49.52900  1.000 319.49000 ? 321 TYR A N     1 
ATOM   2323 C  CA    . TYR A 1 321 ? 55.70400  35.52800  48.57900  1.000 317.65000 ? 321 TYR A CA    1 
ATOM   2324 C  C     . TYR A 1 321 ? 57.06400  35.83000  49.19800  1.000 324.54000 ? 321 TYR A C     1 
ATOM   2325 O  O     . TYR A 1 321 ? 57.17000  36.05600  50.39700  1.000 329.69000 ? 321 TYR A O     1 
ATOM   2326 C  CB    . TYR A 1 321 ? 55.02400  36.82800  48.15000  1.000 314.69000 ? 321 TYR A CB    1 
ATOM   2327 C  CG    . TYR A 1 321 ? 55.43200  37.15800  46.73800  1.000 324.46000 ? 321 TYR A CG    1 
ATOM   2328 C  CD1   . TYR A 1 321 ? 54.77800  38.13100  45.99700  1.000 329.57000 ? 321 TYR A CD1   1 
ATOM   2329 C  CD2   . TYR A 1 321 ? 56.46200  36.45300  46.12600  1.000 332.37000 ? 321 TYR A CD2   1 
ATOM   2330 C  CE1   . TYR A 1 321 ? 55.15900  38.39700  44.68700  1.000 339.83000 ? 321 TYR A CE1   1 
ATOM   2331 C  CE2   . TYR A 1 321 ? 56.85700  36.71300  44.84200  1.000 341.43000 ? 321 TYR A CE2   1 
ATOM   2332 C  CZ    . TYR A 1 321 ? 56.20300  37.68100  44.11800  1.000 342.23000 ? 321 TYR A CZ    1 
ATOM   2333 O  OH    . TYR A 1 321 ? 56.60800  37.91800  42.82300  1.000 336.27000 ? 321 TYR A OH    1 
ATOM   2334 N  N     . ASN A 1 322 ? 58.11300  35.80800  48.38600  1.000 329.33000 ? 322 ASN A N     1 
ATOM   2335 C  CA    . ASN A 1 322 ? 59.42300  36.18000  48.84000  1.000 341.62000 ? 322 ASN A CA    1 
ATOM   2336 C  C     . ASN A 1 322 ? 59.91500  37.39500  48.07500  1.000 348.75000 ? 322 ASN A C     1 
ATOM   2337 O  O     . ASN A 1 322 ? 59.85600  37.43500  46.83100  1.000 344.68000 ? 322 ASN A O     1 
ATOM   2338 C  CB    . ASN A 1 322 ? 60.43400  34.99900  48.70300  1.000 346.48000 ? 322 ASN A CB    1 
ATOM   2339 C  CG    . ASN A 1 322 ? 61.86000  35.36800  49.13000  1.000 354.33000 ? 322 ASN A CG    1 
ATOM   2340 O  OD1   . ASN A 1 322 ? 62.47700  36.25000  48.51300  1.000 361.82000 ? 322 ASN A OD1   1 
ATOM   2341 N  ND2   . ASN A 1 322 ? 62.39700  34.68700  50.13700  1.000 346.95000 ? 322 ASN A ND2   1 
ATOM   2342 N  N     . PRO A 1 323 ? 60.44600  38.37800  48.78400  1.000 363.25000 ? 323 PRO A N     1 
ATOM   2343 C  CA    . PRO A 1 323 ? 61.02300  39.56900  48.14100  1.000 365.69000 ? 323 PRO A CA    1 
ATOM   2344 C  C     . PRO A 1 323 ? 62.33800  39.23300  47.43100  1.000 364.64000 ? 323 PRO A C     1 
ATOM   2345 O  O     . PRO A 1 323 ? 62.47500  39.38300  46.20900  1.000 363.59000 ? 323 PRO A O     1 
ATOM   2346 C  CB    . PRO A 1 323 ? 61.20500  40.54800  49.32000  1.000 368.18000 ? 323 PRO A CB    1 
ATOM   2347 C  CG    . PRO A 1 323 ? 61.21600  39.71900  50.58400  1.000 365.49000 ? 323 PRO A CG    1 
ATOM   2348 C  CD    . PRO A 1 323 ? 60.51700  38.37800  50.27000  1.000 364.70000 ? 323 PRO A CD    1 
ATOM   2349 N  N     . GLU A 1 324 ? 63.28900  38.69900  48.21000  1.000 370.68000 ? 324 GLU A N     1 
ATOM   2350 C  CA    . GLU A 1 324 ? 64.64400  38.44500  47.71900  1.000 366.71000 ? 324 GLU A CA    1 
ATOM   2351 C  C     . GLU A 1 324 ? 64.63700  37.47300  46.54000  1.000 360.80000 ? 324 GLU A C     1 
ATOM   2352 O  O     . GLU A 1 324 ? 65.27700  37.72900  45.51400  1.000 362.18000 ? 324 GLU A O     1 
ATOM   2353 C  CB    . GLU A 1 324 ? 65.53100  37.92100  48.87400  1.000 369.80000 ? 324 GLU A CB    1 
ATOM   2354 C  CG    . GLU A 1 324 ? 66.04700  39.03400  49.89100  1.000 367.39000 ? 324 GLU A CG    1 
ATOM   2355 C  CD    . GLU A 1 324 ? 65.67100  38.83400  51.39200  1.000 357.58000 ? 324 GLU A CD    1 
ATOM   2356 O  OE1   . GLU A 1 324 ? 65.73300  37.69500  51.91800  1.000 362.37000 ? 324 GLU A OE1   1 
ATOM   2357 O  OE2   . GLU A 1 324 ? 65.33600  39.84800  52.05600  1.000 344.35000 ? 324 GLU A OE2   1 
ATOM   2358 N  N     . LYS A 1 325 ? 63.87200  36.38100  46.65100  1.000 364.80000 ? 325 LYS A N     1 
ATOM   2359 C  CA    . LYS A 1 325 ? 63.91700  35.22400  45.74600  1.000 369.15000 ? 325 LYS A CA    1 
ATOM   2360 C  C     . LYS A 1 325 ? 62.87600  35.27200  44.61200  1.000 365.87000 ? 325 LYS A C     1 
ATOM   2361 O  O     . LYS A 1 325 ? 62.93500  34.43400  43.69500  1.000 365.70000 ? 325 LYS A O     1 
ATOM   2362 C  CB    . LYS A 1 325 ? 63.72500  33.91300  46.54600  1.000 364.26000 ? 325 LYS A CB    1 
ATOM   2363 C  CG    . LYS A 1 325 ? 65.02400  33.18700  46.97900  1.000 353.61000 ? 325 LYS A CG    1 
ATOM   2364 C  CD    . LYS A 1 325 ? 66.11000  34.14800  47.44200  1.000 353.02000 ? 325 LYS A CD    1 
ATOM   2365 C  CE    . LYS A 1 325 ? 67.34400  33.41700  47.94800  1.000 344.93000 ? 325 LYS A CE    1 
ATOM   2366 N  NZ    . LYS A 1 325 ? 67.89100  34.18100  49.09900  1.000 345.16000 ? 325 LYS A NZ    1 
ATOM   2367 N  N     . GLY A 1 326 ? 61.94700  36.24000  44.61800  1.000 356.72000 ? 326 GLY A N     1 
ATOM   2368 C  CA    . GLY A 1 326 ? 60.88300  36.26000  43.62000  1.000 346.71000 ? 326 GLY A CA    1 
ATOM   2369 C  C     . GLY A 1 326 ? 60.23900  34.89600  43.45700  1.000 343.76000 ? 326 GLY A C     1 
ATOM   2370 O  O     . GLY A 1 326 ? 60.19000  34.32600  42.35700  1.000 333.86000 ? 326 GLY A O     1 
ATOM   2371 N  N     . GLU A 1 327 ? 59.77600  34.35600  44.58500  1.000 341.35000 ? 327 GLU A N     1 
ATOM   2372 C  CA    . GLU A 1 327 ? 59.42400  32.95300  44.72700  1.000 333.26000 ? 327 GLU A CA    1 
ATOM   2373 C  C     . GLU A 1 327 ? 58.30400  32.82000  45.74300  1.000 326.25000 ? 327 GLU A C     1 
ATOM   2374 O  O     . GLU A 1 327 ? 58.03900  33.72700  46.53600  1.000 327.82000 ? 327 GLU A O     1 
ATOM   2375 C  CB    . GLU A 1 327 ? 60.62400  32.15200  45.20500  1.000 334.74000 ? 327 GLU A CB    1 
ATOM   2376 C  CG    . GLU A 1 327 ? 60.66400  30.69400  44.83700  1.000 329.36000 ? 327 GLU A CG    1 
ATOM   2377 C  CD    . GLU A 1 327 ? 62.03000  30.14700  45.13200  1.000 335.89000 ? 327 GLU A CD    1 
ATOM   2378 O  OE1   . GLU A 1 327 ? 62.96400  30.51600  44.39500  1.000 348.77000 ? 327 GLU A OE1   1 
ATOM   2379 O  OE2   . GLU A 1 327 ? 62.18500  29.41600  46.12900  1.000 331.18000 ? 327 GLU A OE2   1 
ATOM   2380 N  N     . TYR A 1 328 ? 57.64900  31.67400  45.71300  1.000 317.76000 ? 328 TYR A N     1 
ATOM   2381 C  CA    . TYR A 1 328 ? 56.58600  31.34900  46.64400  1.000 315.36000 ? 328 TYR A CA    1 
ATOM   2382 C  C     . TYR A 1 328 ? 57.02500  30.15100  47.47300  1.000 309.40000 ? 328 TYR A C     1 
ATOM   2383 O  O     . TYR A 1 328 ? 57.67300  29.22900  46.94800  1.000 311.43000 ? 328 TYR A O     1 
ATOM   2384 C  CB    . TYR A 1 328 ? 55.27300  31.03700  45.90000  1.000 324.30000 ? 328 TYR A CB    1 
ATOM   2385 C  CG    . TYR A 1 328 ? 54.35600  32.22000  45.55000  1.000 330.05000 ? 328 TYR A CG    1 
ATOM   2386 C  CD1   . TYR A 1 328 ? 53.73000  32.96900  46.55800  1.000 329.85000 ? 328 TYR A CD1   1 
ATOM   2387 C  CD2   . TYR A 1 328 ? 54.07600  32.55600  44.21100  1.000 327.00000 ? 328 TYR A CD2   1 
ATOM   2388 C  CE1   . TYR A 1 328 ? 52.88100  34.02600  46.24500  1.000 328.84000 ? 328 TYR A CE1   1 
ATOM   2389 C  CE2   . TYR A 1 328 ? 53.22600  33.61900  43.89400  1.000 322.39000 ? 328 TYR A CE2   1 
ATOM   2390 C  CZ    . TYR A 1 328 ? 52.63100  34.34500  44.91900  1.000 327.67000 ? 328 TYR A CZ    1 
ATOM   2391 O  OH    . TYR A 1 328 ? 51.79400  35.39400  44.61700  1.000 328.42000 ? 328 TYR A OH    1 
ATOM   2392 N  N     . HIS A 1 329 ? 56.68300  30.18000  48.76700  1.000 295.28000 ? 329 HIS A N     1 
ATOM   2393 C  CA    . HIS A 1 329 ? 57.07400  29.11000  49.67300  1.000 294.38000 ? 329 HIS A CA    1 
ATOM   2394 C  C     . HIS A 1 329 ? 56.20800  29.13000  50.91900  1.000 296.29000 ? 329 HIS A C     1 
ATOM   2395 O  O     . HIS A 1 329 ? 55.44800  30.06500  51.17500  1.000 296.61000 ? 329 HIS A O     1 
ATOM   2396 C  CB    . HIS A 1 329 ? 58.54600  29.22800  50.07000  1.000 296.43000 ? 329 HIS A CB    1 
ATOM   2397 C  CG    . HIS A 1 329 ? 59.46800  28.71400  49.02900  1.000 299.10000 ? 329 HIS A CG    1 
ATOM   2398 N  ND1   . HIS A 1 329 ? 59.15200  27.61600  48.26500  1.000 308.14000 ? 329 HIS A ND1   1 
ATOM   2399 C  CD2   . HIS A 1 329 ? 60.66500  29.16200  48.58700  1.000 306.09000 ? 329 HIS A CD2   1 
ATOM   2400 C  CE1   . HIS A 1 329 ? 60.13200  27.39700  47.41300  1.000 308.15000 ? 329 HIS A CE1   1 
ATOM   2401 N  NE2   . HIS A 1 329 ? 61.06300  28.31600  47.58900  1.000 311.68000 ? 329 HIS A NE2   1 
ATOM   2402 N  N     . LEU A 1 330 ? 56.36500  28.08200  51.70600  1.000 293.99000 ? 330 LEU A N     1 
ATOM   2403 C  CA    . LEU A 1 330 ? 55.44800  27.75300  52.78100  1.000 303.18000 ? 330 LEU A CA    1 
ATOM   2404 C  C     . LEU A 1 330 ? 56.23700  27.43600  54.04200  1.000 309.39000 ? 330 LEU A C     1 
ATOM   2405 O  O     . LEU A 1 330 ? 57.31800  26.83300  53.98100  1.000 311.33000 ? 330 LEU A O     1 
ATOM   2406 C  CB    . LEU A 1 330 ? 54.56800  26.56400  52.37800  1.000 307.48000 ? 330 LEU A CB    1 
ATOM   2407 C  CG    . LEU A 1 330 ? 53.13800  26.78800  51.89100  1.000 308.54000 ? 330 LEU A CG    1 
ATOM   2408 C  CD1   . LEU A 1 330 ? 52.53600  25.42100  51.40800  1.000 307.39000 ? 330 LEU A CD1   1 
ATOM   2409 C  CD2   . LEU A 1 330 ? 52.30800  27.47200  52.99300  1.000 305.68000 ? 330 LEU A CD2   1 
ATOM   2410 N  N     . LYS A 1 331 ? 55.67800  27.85900  55.18100  1.000 306.85000 ? 331 LYS A N     1 
ATOM   2411 C  CA    . LYS A 1 331 ? 56.15800  27.39200  56.46400  1.000 304.54000 ? 331 LYS A CA    1 
ATOM   2412 C  C     . LYS A 1 331 ? 55.64300  25.98700  56.73900  1.000 303.11000 ? 331 LYS A C     1 
ATOM   2413 O  O     . LYS A 1 331 ? 54.52000  25.64000  56.34200  1.000 302.04000 ? 331 LYS A O     1 
ATOM   2414 C  CB    . LYS A 1 331 ? 55.70000  28.31800  57.57200  1.000 301.19000 ? 331 LYS A CB    1 
ATOM   2415 C  CG    . LYS A 1 331 ? 56.62300  29.45600  57.88700  1.000 311.67000 ? 331 LYS A CG    1 
ATOM   2416 C  CD    . LYS A 1 331 ? 55.81100  30.67700  58.24800  1.000 317.58000 ? 331 LYS A CD    1 
ATOM   2417 C  CE    . LYS A 1 331 ? 54.94200  30.47700  59.49100  1.000 314.57000 ? 331 LYS A CE    1 
ATOM   2418 N  NZ    . LYS A 1 331 ? 54.35900  31.76900  59.98400  1.000 305.29000 ? 331 LYS A NZ    1 
ATOM   2419 N  N     . PRO A 1 332 ? 56.42900  25.18400  57.46600  1.000 303.44000 ? 332 PRO A N     1 
ATOM   2420 C  CA    . PRO A 1 332 ? 56.04100  23.77600  57.67900  1.000 299.57000 ? 332 PRO A CA    1 
ATOM   2421 C  C     . PRO A 1 332 ? 54.62900  23.58100  58.18300  1.000 297.47000 ? 332 PRO A C     1 
ATOM   2422 O  O     . PRO A 1 332 ? 53.86300  22.77900  57.62400  1.000 304.79000 ? 332 PRO A O     1 
ATOM   2423 C  CB    . PRO A 1 332 ? 57.04900  23.28200  58.73100  1.000 297.69000 ? 332 PRO A CB    1 
ATOM   2424 C  CG    . PRO A 1 332 ? 58.18400  24.27000  58.66700  1.000 300.58000 ? 332 PRO A CG    1 
ATOM   2425 C  CD    . PRO A 1 332 ? 57.55300  25.59100  58.34000  1.000 299.77000 ? 332 PRO A CD    1 
ATOM   2426 N  N     . LYS A 1 333 ? 54.25500  24.33300  59.21600  1.000 282.18000 ? 333 LYS A N     1 
ATOM   2427 C  CA    . LYS A 1 333 ? 53.01300  24.03400  59.91500  1.000 283.90000 ? 333 LYS A CA    1 
ATOM   2428 C  C     . LYS A 1 333 ? 51.80100  24.21300  59.00900  1.000 278.02000 ? 333 LYS A C     1 
ATOM   2429 O  O     . LYS A 1 333 ? 50.89500  23.36300  59.00900  1.000 285.40000 ? 333 LYS A O     1 
ATOM   2430 C  CB    . LYS A 1 333 ? 52.90300  24.88000  61.17900  1.000 290.81000 ? 333 LYS A CB    1 
ATOM   2431 C  CG    . LYS A 1 333 ? 52.61900  24.04100  62.44800  1.000 296.64000 ? 333 LYS A CG    1 
ATOM   2432 C  CD    . LYS A 1 333 ? 53.55500  22.83600  62.58400  1.000 294.65000 ? 333 LYS A CD    1 
ATOM   2433 C  CE    . LYS A 1 333 ? 52.98100  21.84700  63.57700  1.000 295.21000 ? 333 LYS A CE    1 
ATOM   2434 N  NZ    . LYS A 1 333 ? 52.32400  22.57500  64.69500  1.000 291.39000 ? 333 LYS A NZ    1 
ATOM   2435 N  N     . GLU A 1 334 ? 51.77100  25.27300  58.19700  1.000 287.35000 ? 334 GLU A N     1 
ATOM   2436 C  CA    . GLU A 1 334 ? 50.70300  25.29500  57.21000  1.000 283.53000 ? 334 GLU A CA    1 
ATOM   2437 C  C     . GLU A 1 334 ? 50.89300  24.20700  56.17300  1.000 277.02000 ? 334 GLU A C     1 
ATOM   2438 O  O     . GLU A 1 334 ? 49.91500  23.59000  55.72500  1.000 272.58000 ? 334 GLU A O     1 
ATOM   2439 C  CB    . GLU A 1 334 ? 50.62500  26.64600  56.52000  1.000 287.65000 ? 334 GLU A CB    1 
ATOM   2440 C  CG    . GLU A 1 334 ? 49.60100  26.63000  55.44000  1.000 293.85000 ? 334 GLU A CG    1 
ATOM   2441 C  CD    . GLU A 1 334 ? 48.42300  27.44800  55.82700  1.000 296.81000 ? 334 GLU A CD    1 
ATOM   2442 O  OE1   . GLU A 1 334 ? 48.16000  27.51900  57.03600  1.000 315.03000 ? 334 GLU A OE1   1 
ATOM   2443 O  OE2   . GLU A 1 334 ? 47.79100  28.03700  54.93200  1.000 296.91000 ? 334 GLU A OE2   1 
ATOM   2444 N  N     . ALA A 1 335 ? 52.14600  23.95500  55.79700  1.000 286.04000 ? 335 ALA A N     1 
ATOM   2445 C  CA    . ALA A 1 335 ? 52.44100  22.96100  54.77700  1.000 288.19000 ? 335 ALA A CA    1 
ATOM   2446 C  C     . ALA A 1 335 ? 52.03300  21.56500  55.20500  1.000 281.98000 ? 335 ALA A C     1 
ATOM   2447 O  O     . ALA A 1 335 ? 51.52400  20.78600  54.38800  1.000 280.41000 ? 335 ALA A O     1 
ATOM   2448 C  CB    . ALA A 1 335 ? 53.93700  22.98800  54.45400  1.000 296.21000 ? 335 ALA A CB    1 
ATOM   2449 N  N     . LYS A 1 336 ? 52.26700  21.21400  56.46700  1.000 285.19000 ? 336 LYS A N     1 
ATOM   2450 C  CA    . LYS A 1 336 ? 51.81700  19.90300  56.91500  1.000 282.60000 ? 336 LYS A CA    1 
ATOM   2451 C  C     . LYS A 1 336 ? 50.30400  19.76600  56.78800  1.000 279.16000 ? 336 LYS A C     1 
ATOM   2452 O  O     . LYS A 1 336 ? 49.80300  18.70900  56.37000  1.000 279.45000 ? 336 LYS A O     1 
ATOM   2453 C  CB    . LYS A 1 336 ? 52.30200  19.66600  58.34800  1.000 285.37000 ? 336 LYS A CB    1 
ATOM   2454 C  CG    . LYS A 1 336 ? 53.81900  19.79600  58.42300  1.000 281.59000 ? 336 LYS A CG    1 
ATOM   2455 C  CD    . LYS A 1 336 ? 54.39500  19.34700  59.74700  1.000 286.90000 ? 336 LYS A CD    1 
ATOM   2456 C  CE    . LYS A 1 336 ? 55.90800  19.22900  59.63700  1.000 290.05000 ? 336 LYS A CE    1 
ATOM   2457 N  NZ    . LYS A 1 336 ? 56.58100  19.60500  60.91500  1.000 293.22000 ? 336 LYS A NZ    1 
ATOM   2458 N  N     . ALA A 1 337 ? 49.57200  20.85300  57.06200  1.000 280.06000 ? 337 ALA A N     1 
ATOM   2459 C  CA    . ALA A 1 337 ? 48.11500  20.81000  57.01900  1.000 279.95000 ? 337 ALA A CA    1 
ATOM   2460 C  C     . ALA A 1 337 ? 47.61600  20.55100  55.62500  1.000 274.83000 ? 337 ALA A C     1 
ATOM   2461 O  O     . ALA A 1 337 ? 46.59700  19.88100  55.42900  1.000 275.96000 ? 337 ALA A O     1 
ATOM   2462 C  CB    . ALA A 1 337 ? 47.53100  22.13700  57.49300  1.000 286.81000 ? 337 ALA A CB    1 
ATOM   2463 N  N     . LEU A 1 338 ? 48.29500  21.13100  54.65100  1.000 280.82000 ? 338 LEU A N     1 
ATOM   2464 C  CA    . LEU A 1 338 ? 47.87400  20.96200  53.27800  1.000 279.25000 ? 338 LEU A CA    1 
ATOM   2465 C  C     . LEU A 1 338 ? 48.11600  19.53200  52.81600  1.000 282.37000 ? 338 LEU A C     1 
ATOM   2466 O  O     . LEU A 1 338 ? 47.18800  18.86400  52.33100  1.000 283.55000 ? 338 LEU A O     1 
ATOM   2467 C  CB    . LEU A 1 338 ? 48.58700  21.97500  52.40100  1.000 283.42000 ? 338 LEU A CB    1 
ATOM   2468 C  CG    . LEU A 1 338 ? 47.71400  22.61800  51.32800  1.000 289.67000 ? 338 LEU A CG    1 
ATOM   2469 C  CD1   . LEU A 1 338 ? 46.35500  23.07900  51.87600  1.000 285.59000 ? 338 LEU A CD1   1 
ATOM   2470 C  CD2   . LEU A 1 338 ? 48.40800  23.77800  50.61900  1.000 294.38000 ? 338 LEU A CD2   1 
ATOM   2471 N  N     . LEU A 1 339 ? 49.33700  19.01900  53.02100  1.000 284.95000 ? 339 LEU A N     1 
ATOM   2472 C  CA    . LEU A 1 339 ? 49.60300  17.63800  52.64400  1.000 284.60000 ? 339 LEU A CA    1 
ATOM   2473 C  C     . LEU A 1 339 ? 48.59500  16.69700  53.28700  1.000 290.55000 ? 339 LEU A C     1 
ATOM   2474 O  O     . LEU A 1 339 ? 47.93800  15.91700  52.57900  1.000 288.69000 ? 339 LEU A O     1 
ATOM   2475 C  CB    . LEU A 1 339 ? 51.04200  17.26900  53.02100  1.000 279.88000 ? 339 LEU A CB    1 
ATOM   2476 C  CG    . LEU A 1 339 ? 51.81500  16.55700  51.92600  1.000 278.37000 ? 339 LEU A CG    1 
ATOM   2477 C  CD1   . LEU A 1 339 ? 51.83100  15.08100  52.19400  1.000 285.80000 ? 339 LEU A CD1   1 
ATOM   2478 C  CD2   . LEU A 1 339 ? 51.21200  16.85100  50.55400  1.000 285.38000 ? 339 LEU A CD2   1 
ATOM   2479 N  N     . THR A 1 340 ? 48.41000  16.81500  54.62000  1.000 294.50000 ? 340 THR A N     1 
ATOM   2480 C  CA    . THR A 1 340 ? 47.47600  15.94500  55.34100  1.000 298.87000 ? 340 THR A CA    1 
ATOM   2481 C  C     . THR A 1 340 ? 46.04000  16.14800  54.86200  1.000 297.03000 ? 340 THR A C     1 
ATOM   2482 O  O     . THR A 1 340 ? 45.30100  15.16700  54.66900  1.000 299.90000 ? 340 THR A O     1 
ATOM   2483 C  CB    . THR A 1 340 ? 47.54800  16.18700  56.85300  1.000 287.65000 ? 340 THR A CB    1 
ATOM   2484 O  OG1   . THR A 1 340 ? 48.65200  17.03100  57.15800  1.000 289.54000 ? 340 THR A OG1   1 
ATOM   2485 C  CG2   . THR A 1 340 ? 47.65200  14.87100  57.64100  1.000 282.02000 ? 340 THR A CG2   1 
ATOM   2486 N  N     . GLN A 1 341 ? 45.62100  17.41500  54.67200  1.000 298.40000 ? 341 GLN A N     1 
ATOM   2487 C  CA    . GLN A 1 341 ? 44.30300  17.67000  54.09700  1.000 297.73000 ? 341 GLN A CA    1 
ATOM   2488 C  C     . GLN A 1 341 ? 44.15000  16.93300  52.77900  1.000 294.96000 ? 341 GLN A C     1 
ATOM   2489 O  O     . GLN A 1 341 ? 43.07800  16.39200  52.47200  1.000 293.12000 ? 341 GLN A O     1 
ATOM   2490 C  CB    . GLN A 1 341 ? 44.10400  19.17300  53.87700  1.000 298.83000 ? 341 GLN A CB    1 
ATOM   2491 C  CG    . GLN A 1 341 ? 42.71100  19.70300  54.21000  1.000 303.95000 ? 341 GLN A CG    1 
ATOM   2492 C  CD    . GLN A 1 341 ? 42.58700  21.21800  54.00800  1.000 303.00000 ? 341 GLN A CD    1 
ATOM   2493 O  OE1   . GLN A 1 341 ? 43.58800  21.93900  54.00000  1.000 299.08000 ? 341 GLN A OE1   1 
ATOM   2494 N  NE2   . GLN A 1 341 ? 41.34800  21.70000  53.82800  1.000 304.39000 ? 341 GLN A NE2   1 
ATOM   2495 N  N     . ALA A 1 342 ? 45.22200  16.90200  51.98700  1.000 293.17000 ? 342 ALA A N     1 
ATOM   2496 C  CA    . ALA A 1 342 ? 45.16600  16.18300  50.72600  1.000 289.13000 ? 342 ALA A CA    1 
ATOM   2497 C  C     . ALA A 1 342 ? 45.18100  14.68400  50.93800  1.000 293.60000 ? 342 ALA A C     1 
ATOM   2498 O  O     . ALA A 1 342 ? 44.29200  13.97200  50.44600  1.000 292.67000 ? 342 ALA A O     1 
ATOM   2499 C  CB    . ALA A 1 342 ? 46.32000  16.59000  49.84200  1.000 284.22000 ? 342 ALA A CB    1 
ATOM   2500 N  N     . LEU A 1 343 ? 46.17000  14.19700  51.68400  1.000 295.18000 ? 343 LEU A N     1 
ATOM   2501 C  CA    . LEU A 1 343 ? 46.25000  12.77400  51.96800  1.000 302.77000 ? 343 LEU A CA    1 
ATOM   2502 C  C     . LEU A 1 343 ? 44.96500  12.26400  52.60300  1.000 305.09000 ? 343 LEU A C     1 
ATOM   2503 O  O     . LEU A 1 343 ? 44.39800  11.25800  52.15100  1.000 305.70000 ? 343 LEU A O     1 
ATOM   2504 C  CB    . LEU A 1 343 ? 47.43600  12.49100  52.88100  1.000 310.88000 ? 343 LEU A CB    1 
ATOM   2505 C  CG    . LEU A 1 343 ? 48.79500  12.94600  52.38300  1.000 307.23000 ? 343 LEU A CG    1 
ATOM   2506 C  CD1   . LEU A 1 343 ? 49.86100  12.31200  53.24500  1.000 311.62000 ? 343 LEU A CD1   1 
ATOM   2507 C  CD2   . LEU A 1 343 ? 48.99300  12.59200  50.91300  1.000 292.29000 ? 343 LEU A CD2   1 
ATOM   2508 N  N     . GLU A 1 344 ? 44.49400  12.93300  53.66200  1.000 310.50000 ? 344 GLU A N     1 
ATOM   2509 C  CA    . GLU A 1 344 ? 43.32500  12.41100  54.35700  1.000 311.03000 ? 344 GLU A CA    1 
ATOM   2510 C  C     . GLU A 1 344 ? 42.08700  12.44100  53.46900  1.000 305.22000 ? 344 GLU A C     1 
ATOM   2511 O  O     . GLU A 1 344 ? 41.36100  11.43300  53.38300  1.000 304.57000 ? 344 GLU A O     1 
ATOM   2512 C  CB    . GLU A 1 344 ? 43.09500  13.18200  55.65900  1.000 312.03000 ? 344 GLU A CB    1 
ATOM   2513 C  CG    . GLU A 1 344 ? 44.09700  12.86000  56.78500  1.000 303.88000 ? 344 GLU A CG    1 
ATOM   2514 C  CD    . GLU A 1 344 ? 44.03200  11.41200  57.24900  1.000 301.10000 ? 344 GLU A CD    1 
ATOM   2515 O  OE1   . GLU A 1 344 ? 42.91200  10.88600  57.44600  1.000 307.55000 ? 344 GLU A OE1   1 
ATOM   2516 O  OE2   . GLU A 1 344 ? 45.10500  10.79600  57.40600  1.000 299.79000 ? 344 GLU A OE2   1 
ATOM   2517 N  N     . SER A 1 345 ? 41.85200  13.55700  52.76600  1.000 299.60000 ? 345 SER A N     1 
ATOM   2518 C  CA    . SER A 1 345 ? 40.73600  13.56300  51.83300  1.000 297.57000 ? 345 SER A CA    1 
ATOM   2519 C  C     . SER A 1 345 ? 40.91800  12.49000  50.76400  1.000 303.21000 ? 345 SER A C     1 
ATOM   2520 O  O     . SER A 1 345 ? 39.93800  11.86700  50.33800  1.000 307.03000 ? 345 SER A O     1 
ATOM   2521 C  CB    . SER A 1 345 ? 40.58500  14.96200  51.21800  1.000 295.10000 ? 345 SER A CB    1 
ATOM   2522 O  OG    . SER A 1 345 ? 39.52800  15.06400  50.29300  1.000 309.59000 ? 345 SER A OG    1 
ATOM   2523 N  N     . TYR A 1 346 ? 42.17200  12.20300  50.38100  1.000 299.59000 ? 346 TYR A N     1 
ATOM   2524 C  CA    . TYR A 1 346 ? 42.44200  11.07500  49.48500  1.000 295.50000 ? 346 TYR A CA    1 
ATOM   2525 C  C     . TYR A 1 346 ? 41.98800  9.76600   50.11300  1.000 296.98000 ? 346 TYR A C     1 
ATOM   2526 O  O     . TYR A 1 346 ? 41.31900  8.95200   49.46300  1.000 298.86000 ? 346 TYR A O     1 
ATOM   2527 C  CB    . TYR A 1 346 ? 43.94300  10.97800  49.12900  1.000 288.87000 ? 346 TYR A CB    1 
ATOM   2528 C  CG    . TYR A 1 346 ? 44.29000  9.83900   48.17100  1.000 282.98000 ? 346 TYR A CG    1 
ATOM   2529 C  CD1   . TYR A 1 346 ? 44.41300  10.05700  46.81300  1.000 284.86000 ? 346 TYR A CD1   1 
ATOM   2530 C  CD2   . TYR A 1 346 ? 44.46400  8.54300   48.63200  1.000 286.66000 ? 346 TYR A CD2   1 
ATOM   2531 C  CE1   . TYR A 1 346 ? 44.70100  9.02300   45.96400  1.000 281.35000 ? 346 TYR A CE1   1 
ATOM   2532 C  CE2   . TYR A 1 346 ? 44.75100  7.51700   47.77600  1.000 286.63000 ? 346 TYR A CE2   1 
ATOM   2533 C  CZ    . TYR A 1 346 ? 44.86800  7.77100   46.44300  1.000 283.71000 ? 346 TYR A CZ    1 
ATOM   2534 O  OH    . TYR A 1 346 ? 45.15300  6.74800   45.57800  1.000 285.17000 ? 346 TYR A OH    1 
ATOM   2535 N  N     . LYS A 1 347 ? 42.35700  9.53500   51.38300  1.000 292.56000 ? 347 LYS A N     1 
ATOM   2536 C  CA    . LYS A 1 347 ? 42.07400  8.23700   51.99000  1.000 291.21000 ? 347 LYS A CA    1 
ATOM   2537 C  C     . LYS A 1 347 ? 40.58600  8.05900   52.20900  1.000 294.80000 ? 347 LYS A C     1 
ATOM   2538 O  O     . LYS A 1 347 ? 40.04100  6.97200   51.94800  1.000 298.26000 ? 347 LYS A O     1 
ATOM   2539 C  CB    . LYS A 1 347 ? 42.84300  8.06300   53.30400  1.000 286.11000 ? 347 LYS A CB    1 
ATOM   2540 C  CG    . LYS A 1 347 ? 42.85500  6.64800   53.85500  1.000 290.14000 ? 347 LYS A CG    1 
ATOM   2541 C  CD    . LYS A 1 347 ? 43.10900  6.64100   55.35000  1.000 294.56000 ? 347 LYS A CD    1 
ATOM   2542 C  CE    . LYS A 1 347 ? 42.67200  5.33300   55.97800  1.000 294.49000 ? 347 LYS A CE    1 
ATOM   2543 N  NZ    . LYS A 1 347 ? 41.20500  5.29700   56.25500  1.000 298.31000 ? 347 LYS A NZ    1 
ATOM   2544 N  N     . GLU A 1 348 ? 39.90900  9.12900   52.65700  1.000 297.13000 ? 348 GLU A N     1 
ATOM   2545 C  CA    . GLU A 1 348 ? 38.45700  9.09300   52.71300  1.000 302.87000 ? 348 GLU A CA    1 
ATOM   2546 C  C     . GLU A 1 348 ? 37.85200  8.79000   51.34300  1.000 307.46000 ? 348 GLU A C     1 
ATOM   2547 O  O     . GLU A 1 348 ? 36.79300  8.17400   51.26700  1.000 316.24000 ? 348 GLU A O     1 
ATOM   2548 C  CB    . GLU A 1 348 ? 37.91400  10.42300  53.25500  1.000 304.95000 ? 348 GLU A CB    1 
ATOM   2549 C  CG    . GLU A 1 348 ? 37.66200  10.46900  54.75700  1.000 320.46000 ? 348 GLU A CG    1 
ATOM   2550 C  CD    . GLU A 1 348 ? 36.83300  11.67900  55.19200  1.000 313.95000 ? 348 GLU A CD    1 
ATOM   2551 O  OE1   . GLU A 1 348 ? 36.05000  11.53300  56.16100  1.000 306.10000 ? 348 GLU A OE1   1 
ATOM   2552 O  OE2   . GLU A 1 348 ? 36.95000  12.76300  54.58000  1.000 316.72000 ? 348 GLU A OE2   1 
ATOM   2553 N  N     . GLN A 1 349 ? 38.50100  9.23100   50.25000  1.000 301.31000 ? 349 GLN A N     1 
ATOM   2554 C  CA    . GLN A 1 349 ? 37.97300  9.03500   48.88600  1.000 298.52000 ? 349 GLN A CA    1 
ATOM   2555 C  C     . GLN A 1 349 ? 38.29100  7.63300   48.36100  1.000 293.78000 ? 349 GLN A C     1 
ATOM   2556 O  O     . GLN A 1 349 ? 37.44500  6.98500   47.72600  1.000 289.29000 ? 349 GLN A O     1 
ATOM   2557 C  CB    . GLN A 1 349 ? 38.54600  10.09300  47.93000  1.000 299.37000 ? 349 GLN A CB    1 
ATOM   2558 C  CG    . GLN A 1 349 ? 37.56300  10.98600  47.05400  1.000 308.08000 ? 349 GLN A CG    1 
ATOM   2559 C  CD    . GLN A 1 349 ? 38.28100  12.09700  46.21500  1.000 311.15000 ? 349 GLN A CD    1 
ATOM   2560 O  OE1   . GLN A 1 349 ? 38.83000  13.06100  46.76500  1.000 303.83000 ? 349 GLN A OE1   1 
ATOM   2561 N  NE2   . GLN A 1 349 ? 38.23600  11.96900  44.88800  1.000 308.31000 ? 349 GLN A NE2   1 
ATOM   2562 N  N     . ASN A 1 350 ? 39.50500  7.14500   48.65100  1.000 304.76000 ? 350 ASN A N     1 
ATOM   2563 C  CA    . ASN A 1 350 ? 40.11600  5.95500   48.05300  1.000 303.71000 ? 350 ASN A CA    1 
ATOM   2564 C  C     . ASN A 1 350 ? 40.54000  4.89000   49.06700  1.000 303.21000 ? 350 ASN A C     1 
ATOM   2565 O  O     . ASN A 1 350 ? 41.19300  3.90300   48.66600  1.000 298.17000 ? 350 ASN A O     1 
ATOM   2566 C  CB    . ASN A 1 350 ? 41.36600  6.32900   47.22100  1.000 303.50000 ? 350 ASN A CB    1 
ATOM   2567 C  CG    . ASN A 1 350 ? 41.03900  7.28600   46.07600  1.000 301.94000 ? 350 ASN A CG    1 
ATOM   2568 O  OD1   . ASN A 1 350 ? 40.89700  6.86400   44.91900  1.000 303.83000 ? 350 ASN A OD1   1 
ATOM   2569 N  ND2   . ASN A 1 350 ? 40.95200  8.58100   46.38700  1.000 303.23000 ? 350 ASN A ND2   1 
ATOM   2570 N  N     . LYS A 1 351 ? 40.22900  5.05100   50.35600  1.000 311.92000 ? 351 LYS A N     1 
ATOM   2571 C  CA    . LYS A 1 351 ? 40.39400  3.98900   51.34900  1.000 309.00000 ? 351 LYS A CA    1 
ATOM   2572 C  C     . LYS A 1 351 ? 41.83400  3.53100   51.58800  1.000 303.24000 ? 351 LYS A C     1 
ATOM   2573 O  O     . LYS A 1 351 ? 42.02900  2.41500   52.09000  1.000 309.00000 ? 351 LYS A O     1 
ATOM   2574 C  CB    . LYS A 1 351 ? 39.57900  2.74000   50.98700  1.000 314.05000 ? 351 LYS A CB    1 
ATOM   2575 C  CG    . LYS A 1 351 ? 38.13100  2.78500   51.42600  1.000 303.48000 ? 351 LYS A CG    1 
ATOM   2576 C  CD    . LYS A 1 351 ? 37.39500  3.93100   50.76200  1.000 311.51000 ? 351 LYS A CD    1 
ATOM   2577 C  CE    . LYS A 1 351 ? 36.36900  4.46300   51.71600  1.000 301.56000 ? 351 LYS A CE    1 
ATOM   2578 N  NZ    . LYS A 1 351 ? 35.57100  5.50600   51.04300  1.000 320.58000 ? 351 LYS A NZ    1 
ATOM   2579 N  N     . SER A 1 352 ? 42.84400  4.31100   51.21800  1.000 291.09000 ? 352 SER A N     1 
ATOM   2580 C  CA    . SER A 1 352 ? 44.24200  4.00000   51.49900  1.000 289.02000 ? 352 SER A CA    1 
ATOM   2581 C  C     . SER A 1 352 ? 45.02200  5.28300   51.28900  1.000 291.82000 ? 352 SER A C     1 
ATOM   2582 O  O     . SER A 1 352 ? 44.45700  6.30600   50.89600  1.000 293.18000 ? 352 SER A O     1 
ATOM   2583 C  CB    . SER A 1 352 ? 44.78900  2.88000   50.61200  1.000 290.59000 ? 352 SER A CB    1 
ATOM   2584 O  OG    . SER A 1 352 ? 43.77800  2.06700   50.06600  1.000 301.55000 ? 352 SER A OG    1 
ATOM   2585 N  N     . TYR A 1 353 ? 46.32700  5.22600   51.59200  1.000 285.14000 ? 353 TYR A N     1 
ATOM   2586 C  CA    . TYR A 1 353 ? 47.22100  6.35700   51.35200  1.000 280.20000 ? 353 TYR A CA    1 
ATOM   2587 C  C     . TYR A 1 353 ? 47.98800  6.14100   50.05400  1.000 275.95000 ? 353 TYR A C     1 
ATOM   2588 O  O     . TYR A 1 353 ? 48.50800  5.04500   49.82800  1.000 282.83000 ? 353 TYR A O     1 
ATOM   2589 C  CB    . TYR A 1 353 ? 48.19600  6.53800   52.50700  1.000 281.50000 ? 353 TYR A CB    1 
ATOM   2590 C  CG    . TYR A 1 353 ? 47.61400  7.23100   53.72100  1.000 284.28000 ? 353 TYR A CG    1 
ATOM   2591 C  CD1   . TYR A 1 353 ? 46.94900  6.51300   54.70500  1.000 287.26000 ? 353 TYR A CD1   1 
ATOM   2592 C  CD2   . TYR A 1 353 ? 47.74200  8.60400   53.87700  1.000 283.22000 ? 353 TYR A CD2   1 
ATOM   2593 C  CE1   . TYR A 1 353 ? 46.43400  7.14100   55.79300  1.000 289.30000 ? 353 TYR A CE1   1 
ATOM   2594 C  CE2   . TYR A 1 353 ? 47.23300  9.23800   54.95900  1.000 288.38000 ? 353 TYR A CE2   1 
ATOM   2595 C  CZ    . TYR A 1 353 ? 46.58000  8.50400   55.90900  1.000 289.08000 ? 353 TYR A CZ    1 
ATOM   2596 O  OH    . TYR A 1 353 ? 46.07800  9.15300   56.98700  1.000 284.31000 ? 353 TYR A OH    1 
ATOM   2597 N  N     . PRO A 1 354 ? 48.08800  7.13700   49.18500  1.000 276.76000 ? 354 PRO A N     1 
ATOM   2598 C  CA    . PRO A 1 354 ? 48.62700  6.87300   47.85400  1.000 278.08000 ? 354 PRO A CA    1 
ATOM   2599 C  C     . PRO A 1 354 ? 50.09600  6.51400   47.93900  1.000 278.76000 ? 354 PRO A C     1 
ATOM   2600 O  O     . PRO A 1 354 ? 50.87300  7.17800   48.62000  1.000 279.06000 ? 354 PRO A O     1 
ATOM   2601 C  CB    . PRO A 1 354 ? 48.39600  8.18900   47.11400  1.000 279.05000 ? 354 PRO A CB    1 
ATOM   2602 C  CG    . PRO A 1 354 ? 48.33400  9.21600   48.15900  1.000 275.09000 ? 354 PRO A CG    1 
ATOM   2603 C  CD    . PRO A 1 354 ? 47.89700  8.57100   49.43400  1.000 277.98000 ? 354 PRO A CD    1 
ATOM   2604 N  N     . LYS A 1 355 ? 50.46100  5.43500   47.25700  1.000 282.73000 ? 355 LYS A N     1 
ATOM   2605 C  CA    . LYS A 1 355 ? 51.83800  4.96600   47.22100  1.000 286.07000 ? 355 LYS A CA    1 
ATOM   2606 C  C     . LYS A 1 355 ? 52.77000  5.90700   46.48200  1.000 281.69000 ? 355 LYS A C     1 
ATOM   2607 O  O     . LYS A 1 355 ? 53.98700  5.68400   46.50100  1.000 279.54000 ? 355 LYS A O     1 
ATOM   2608 C  CB    . LYS A 1 355 ? 51.89400  3.58800   46.57500  1.000 293.38000 ? 355 LYS A CB    1 
ATOM   2609 C  CG    . LYS A 1 355 ? 51.58500  2.44600   47.52500  1.000 289.99000 ? 355 LYS A CG    1 
ATOM   2610 C  CD    . LYS A 1 355 ? 52.86400  1.89100   48.13300  1.000 290.05000 ? 355 LYS A CD    1 
ATOM   2611 C  CE    . LYS A 1 355 ? 52.71800  0.42700   48.47800  1.000 279.21000 ? 355 LYS A CE    1 
ATOM   2612 N  NZ    . LYS A 1 355 ? 51.40700  0.17300   49.11000  1.000 273.87000 ? 355 LYS A NZ    1 
ATOM   2613 N  N     . GLU A 1 356 ? 52.23900  6.93500   45.82900  1.000 286.50000 ? 356 GLU A N     1 
ATOM   2614 C  CA    . GLU A 1 356 ? 53.07100  7.91000   45.14100  1.000 286.12000 ? 356 GLU A CA    1 
ATOM   2615 C  C     . GLU A 1 356 ? 52.34300  9.24300   45.11900  1.000 284.19000 ? 356 GLU A C     1 
ATOM   2616 O  O     . GLU A 1 356 ? 51.17100  9.30300   44.73800  1.000 284.65000 ? 356 GLU A O     1 
ATOM   2617 C  CB    . GLU A 1 356 ? 53.40400  7.44500   43.71700  1.000 289.42000 ? 356 GLU A CB    1 
ATOM   2618 C  CG    . GLU A 1 356 ? 54.72900  6.67900   43.62900  1.000 298.53000 ? 356 GLU A CG    1 
ATOM   2619 C  CD    . GLU A 1 356 ? 55.30100  6.60800   42.22000  1.000 308.48000 ? 356 GLU A CD    1 
ATOM   2620 O  OE1   . GLU A 1 356 ? 56.26400  7.34900   41.89700  1.000 316.44000 ? 356 GLU A OE1   1 
ATOM   2621 O  OE2   . GLU A 1 356 ? 54.77500  5.80100   41.43100  1.000 310.11000 ? 356 GLU A OE2   1 
ATOM   2622 N  N     . VAL A 1 357 ? 53.03000  10.30600  45.52600  1.000 282.59000 ? 357 VAL A N     1 
ATOM   2623 C  CA    . VAL A 1 357 ? 52.44800  11.63800  45.52000  1.000 281.77000 ? 357 VAL A CA    1 
ATOM   2624 C  C     . VAL A 1 357 ? 53.42800  12.59500  44.87000  1.000 286.22000 ? 357 VAL A C     1 
ATOM   2625 O  O     . VAL A 1 357 ? 54.51400  12.84000  45.40600  1.000 288.37000 ? 357 VAL A O     1 
ATOM   2626 C  CB    . VAL A 1 357 ? 52.08800  12.12800  46.92600  1.000 282.89000 ? 357 VAL A CB    1 
ATOM   2627 C  CG1   . VAL A 1 357 ? 51.45500  13.48900  46.82700  1.000 284.06000 ? 357 VAL A CG1   1 
ATOM   2628 C  CG2   . VAL A 1 357 ? 51.15800  11.14300  47.61700  1.000 286.79000 ? 357 VAL A CG2   1 
ATOM   2629 N  N     . PHE A 1 358 ? 53.04800  13.13100  43.72100  1.000 283.87000 ? 358 PHE A N     1 
ATOM   2630 C  CA    . PHE A 1 358 ? 53.80900  14.16600  43.04700  1.000 284.77000 ? 358 PHE A CA    1 
ATOM   2631 C  C     . PHE A 1 358 ? 53.19100  15.50900  43.39400  1.000 282.73000 ? 358 PHE A C     1 
ATOM   2632 O  O     . PHE A 1 358 ? 51.97500  15.69600  43.27000  1.000 280.04000 ? 358 PHE A O     1 
ATOM   2633 C  CB    . PHE A 1 358 ? 53.81400  13.97200  41.53200  1.000 280.91000 ? 358 PHE A CB    1 
ATOM   2634 C  CG    . PHE A 1 358 ? 54.37900  12.66000  41.07300  1.000 278.60000 ? 358 PHE A CG    1 
ATOM   2635 C  CD1   . PHE A 1 358 ? 55.65400  12.58800  40.53900  1.000 277.72000 ? 358 PHE A CD1   1 
ATOM   2636 C  CD2   . PHE A 1 358 ? 53.62800  11.50400  41.14700  1.000 280.46000 ? 358 PHE A CD2   1 
ATOM   2637 C  CE1   . PHE A 1 358 ? 56.17100  11.38100  40.09400  1.000 277.01000 ? 358 PHE A CE1   1 
ATOM   2638 C  CE2   . PHE A 1 358 ? 54.14100  10.30200  40.71200  1.000 285.08000 ? 358 PHE A CE2   1 
ATOM   2639 C  CZ    . PHE A 1 358 ? 55.41400  10.24100  40.18600  1.000 282.39000 ? 358 PHE A CZ    1 
ATOM   2640 N  N     . ILE A 1 359 ? 54.02300  16.43000  43.84300  1.000 276.81000 ? 359 ILE A N     1 
ATOM   2641 C  CA    . ILE A 1 359 ? 53.61700  17.80700  44.05800  1.000 270.73000 ? 359 ILE A CA    1 
ATOM   2642 C  C     . ILE A 1 359 ? 54.26700  18.64400  42.97300  1.000 273.44000 ? 359 ILE A C     1 
ATOM   2643 O  O     . ILE A 1 359 ? 55.49300  18.61900  42.80000  1.000 276.18000 ? 359 ILE A O     1 
ATOM   2644 C  CB    . ILE A 1 359 ? 53.99800  18.28500  45.46400  1.000 268.99000 ? 359 ILE A CB    1 
ATOM   2645 C  CG1   . ILE A 1 359 ? 53.07200  17.60700  46.46900  1.000 266.31000 ? 359 ILE A CG1   1 
ATOM   2646 C  CG2   . ILE A 1 359 ? 53.94500  19.80000  45.55900  1.000 272.06000 ? 359 ILE A CG2   1 
ATOM   2647 C  CD1   . ILE A 1 359 ? 53.40100  17.87700  47.89100  1.000 278.13000 ? 359 ILE A CD1   1 
ATOM   2648 N  N     . HIS A 1 360 ? 53.44000  19.34000  42.20500  1.000 269.25000 ? 360 HIS A N     1 
ATOM   2649 C  CA    . HIS A 1 360 ? 53.92800  20.17100  41.12000  1.000 270.17000 ? 360 HIS A CA    1 
ATOM   2650 C  C     . HIS A 1 360 ? 53.84300  21.63000  41.53500  1.000 271.14000 ? 360 HIS A C     1 
ATOM   2651 O  O     . HIS A 1 360 ? 52.91000  22.04600  42.22600  1.000 273.07000 ? 360 HIS A O     1 
ATOM   2652 C  CB    . HIS A 1 360 ? 53.11600  19.94000  39.84200  1.000 272.48000 ? 360 HIS A CB    1 
ATOM   2653 C  CG    . HIS A 1 360 ? 53.05600  18.50500  39.41300  1.000 267.49000 ? 360 HIS A CG    1 
ATOM   2654 N  ND1   . HIS A 1 360 ? 52.07700  18.02200  38.57200  1.000 263.43000 ? 360 HIS A ND1   1 
ATOM   2655 C  CD2   . HIS A 1 360 ? 53.85200  17.45000  39.71000  1.000 269.80000 ? 360 HIS A CD2   1 
ATOM   2656 C  CE1   . HIS A 1 360 ? 52.27100  16.73200  38.37200  1.000 266.94000 ? 360 HIS A CE1   1 
ATOM   2657 N  NE2   . HIS A 1 360 ? 53.34200  16.36000  39.04900  1.000 267.98000 ? 360 HIS A NE2   1 
ATOM   2658 N  N     . ALA A 1 361 ? 54.84000  22.39900  41.12900  1.000 261.88000 ? 361 ALA A N     1 
ATOM   2659 C  CA    . ALA A 1 361 ? 54.75700  23.84300  41.24100  1.000 264.00000 ? 361 ALA A CA    1 
ATOM   2660 C  C     . ALA A 1 361 ? 55.76600  24.39000  40.26500  1.000 268.55000 ? 361 ALA A C     1 
ATOM   2661 O  O     . ALA A 1 361 ? 56.58900  23.65500  39.72500  1.000 266.96000 ? 361 ALA A O     1 
ATOM   2662 C  CB    . ALA A 1 361 ? 55.01900  24.34800  42.66100  1.000 265.89000 ? 361 ALA A CB    1 
ATOM   2663 N  N     . ARG A 1 362 ? 55.68800  25.68200  40.03000  1.000 275.38000 ? 362 ARG A N     1 
ATOM   2664 C  CA    . ARG A 1 362 ? 56.60100  26.27000  39.07400  1.000 277.14000 ? 362 ARG A CA    1 
ATOM   2665 C  C     . ARG A 1 362 ? 57.87700  26.78100  39.70700  1.000 280.82000 ? 362 ARG A C     1 
ATOM   2666 O  O     . ARG A 1 362 ? 58.67400  27.42500  39.02200  1.000 287.29000 ? 362 ARG A O     1 
ATOM   2667 C  CB    . ARG A 1 362 ? 55.93500  27.41100  38.33400  1.000 283.18000 ? 362 ARG A CB    1 
ATOM   2668 C  CG    . ARG A 1 362 ? 54.57200  27.72600  38.84300  1.000 284.69000 ? 362 ARG A CG    1 
ATOM   2669 C  CD    . ARG A 1 362 ? 53.87200  28.52000  37.80100  1.000 289.87000 ? 362 ARG A CD    1 
ATOM   2670 N  NE    . ARG A 1 362 ? 53.14800  27.62500  36.92100  1.000 291.03000 ? 362 ARG A NE    1 
ATOM   2671 C  CZ    . ARG A 1 362 ? 52.37300  28.04100  35.93700  1.000 299.92000 ? 362 ARG A CZ    1 
ATOM   2672 N  NH1   . ARG A 1 362 ? 52.24500  29.34600  35.71000  1.000 303.75000 ? 362 ARG A NH1   1 
ATOM   2673 N  NH2   . ARG A 1 362 ? 51.73200  27.14900  35.20000  1.000 299.56000 ? 362 ARG A NH2   1 
ATOM   2674 N  N     . THR A 1 363 ? 58.10200  26.51100  40.98100  1.000 283.00000 ? 363 THR A N     1 
ATOM   2675 C  CA    . THR A 1 363 ? 59.28200  27.01000  41.66500  1.000 283.31000 ? 363 THR A CA    1 
ATOM   2676 C  C     . THR A 1 363 ? 60.02800  25.83300  42.27400  1.000 296.86000 ? 363 THR A C     1 
ATOM   2677 O  O     . THR A 1 363 ? 59.49500  24.72600  42.33400  1.000 302.19000 ? 363 THR A O     1 
ATOM   2678 C  CB    . THR A 1 363 ? 58.86300  28.03100  42.71400  1.000 289.59000 ? 363 THR A CB    1 
ATOM   2679 O  OG1   . THR A 1 363 ? 57.75300  27.49500  43.44000  1.000 303.08000 ? 363 THR A OG1   1 
ATOM   2680 C  CG2   . THR A 1 363 ? 58.39700  29.31700  42.03800  1.000 284.24000 ? 363 THR A CG2   1 
ATOM   2681 N  N     . ARG A 1 364 ? 61.28200  26.04900  42.67100  1.000 295.35000 ? 364 ARG A N     1 
ATOM   2682 C  CA    . ARG A 1 364 ? 61.97700  24.99300  43.39200  1.000 298.20000 ? 364 ARG A CA    1 
ATOM   2683 C  C     . ARG A 1 364 ? 61.48200  24.96500  44.84300  1.000 298.56000 ? 364 ARG A C     1 
ATOM   2684 O  O     . ARG A 1 364 ? 60.78000  25.87200  45.29300  1.000 304.33000 ? 364 ARG A O     1 
ATOM   2685 C  CB    . ARG A 1 364 ? 63.49300  25.20700  43.31600  1.000 294.37000 ? 364 ARG A CB    1 
ATOM   2686 C  CG    . ARG A 1 364 ? 64.13300  25.28300  41.89500  1.000 292.27000 ? 364 ARG A CG    1 
ATOM   2687 C  CD    . ARG A 1 364 ? 65.59900  25.72200  41.98700  1.000 305.49000 ? 364 ARG A CD    1 
ATOM   2688 N  NE    . ARG A 1 364 ? 66.03300  26.85800  41.16000  1.000 315.74000 ? 364 ARG A NE    1 
ATOM   2689 C  CZ    . ARG A 1 364 ? 65.49600  28.08000  41.14900  1.000 314.51000 ? 364 ARG A CZ    1 
ATOM   2690 N  NH1   . ARG A 1 364 ? 64.42700  28.36800  41.86900  1.000 308.91000 ? 364 ARG A NH1   1 
ATOM   2691 N  NH2   . ARG A 1 364 ? 66.02100  29.03100  40.38500  1.000 316.19000 ? 364 ARG A NH2   1 
ATOM   2692 N  N     . PHE A 1 365 ? 61.78300  23.88200  45.55900  1.000 288.70000 ? 365 PHE A N     1 
ATOM   2693 C  CA    . PHE A 1 365 ? 61.36200  23.76000  46.94900  1.000 287.10000 ? 365 PHE A CA    1 
ATOM   2694 C  C     . PHE A 1 365 ? 62.54100  24.03100  47.86300  1.000 287.02000 ? 365 PHE A C     1 
ATOM   2695 O  O     . PHE A 1 365 ? 63.66500  23.61100  47.57600  1.000 291.18000 ? 365 PHE A O     1 
ATOM   2696 C  CB    . PHE A 1 365 ? 60.77500  22.39000  47.27800  1.000 284.63000 ? 365 PHE A CB    1 
ATOM   2697 C  CG    . PHE A 1 365 ? 59.60200  22.03000  46.45800  1.000 275.11000 ? 365 PHE A CG    1 
ATOM   2698 C  CD1   . PHE A 1 365 ? 58.32300  22.17500  46.94600  1.000 279.54000 ? 365 PHE A CD1   1 
ATOM   2699 C  CD2   . PHE A 1 365 ? 59.77800  21.56400  45.17800  1.000 285.14000 ? 365 PHE A CD2   1 
ATOM   2700 C  CE1   . PHE A 1 365 ? 57.23600  21.84300  46.17700  1.000 266.33000 ? 365 PHE A CE1   1 
ATOM   2701 C  CE2   . PHE A 1 365 ? 58.69200  21.23100  44.39200  1.000 287.71000 ? 365 PHE A CE2   1 
ATOM   2702 C  CZ    . PHE A 1 365 ? 57.41300  21.37000  44.89200  1.000 279.06000 ? 365 PHE A CZ    1 
ATOM   2703 N  N     . ASN A 1 366 ? 62.28600  24.77400  48.93600  1.000 287.42000 ? 366 ASN A N     1 
ATOM   2704 C  CA    . ASN A 1 366 ? 63.27400  24.93400  49.99700  1.000 291.02000 ? 366 ASN A CA    1 
ATOM   2705 C  C     . ASN A 1 366 ? 63.24800  23.70300  50.91600  1.000 298.30000 ? 366 ASN A C     1 
ATOM   2706 O  O     . ASN A 1 366 ? 62.17800  23.13100  51.16400  1.000 302.04000 ? 366 ASN A O     1 
ATOM   2707 C  CB    . ASN A 1 366 ? 63.00000  26.23700  50.77000  1.000 285.75000 ? 366 ASN A CB    1 
ATOM   2708 C  CG    . ASN A 1 366 ? 61.62900  26.27300  51.41300  1.000 286.89000 ? 366 ASN A CG    1 
ATOM   2709 O  OD1   . ASN A 1 366 ? 61.46300  25.84900  52.55700  1.000 290.33000 ? 366 ASN A OD1   1 
ATOM   2710 N  ND2   . ASN A 1 366 ? 60.65000  26.80500  50.69000  1.000 295.63000 ? 366 ASN A ND2   1 
ATOM   2711 N  N     . ASP A 1 367 ? 64.43500  23.26100  51.38700  1.000 297.84000 ? 367 ASP A N     1 
ATOM   2712 C  CA    . ASP A 1 367 ? 64.52900  21.94100  52.03300  1.000 298.35000 ? 367 ASP A CA    1 
ATOM   2713 C  C     . ASP A 1 367 ? 63.67100  21.85800  53.30200  1.000 293.74000 ? 367 ASP A C     1 
ATOM   2714 O  O     . ASP A 1 367 ? 63.28700  20.75800  53.74000  1.000 292.82000 ? 367 ASP A O     1 
ATOM   2715 C  CB    . ASP A 1 367 ? 65.99600  21.60300  52.34500  1.000 297.28000 ? 367 ASP A CB    1 
ATOM   2716 C  CG    . ASP A 1 367 ? 66.51500  20.38200  51.56500  1.000 299.86000 ? 367 ASP A CG    1 
ATOM   2717 O  OD1   . ASP A 1 367 ? 65.72600  19.47800  51.23500  1.000 300.89000 ? 367 ASP A OD1   1 
ATOM   2718 O  OD2   . ASP A 1 367 ? 67.74100  20.32000  51.28700  1.000 305.48000 ? 367 ASP A OD2   1 
ATOM   2719 N  N     . GLU A 1 368 ? 63.35100  23.00900  53.90100  1.000 297.15000 ? 368 GLU A N     1 
ATOM   2720 C  CA    . GLU A 1 368 ? 62.52200  23.00200  55.10000  1.000 298.50000 ? 368 GLU A CA    1 
ATOM   2721 C  C     . GLU A 1 368 ? 61.06800  22.71900  54.75800  1.000 294.53000 ? 368 GLU A C     1 
ATOM   2722 O  O     . GLU A 1 368 ? 60.43900  21.81600  55.33200  1.000 295.32000 ? 368 GLU A O     1 
ATOM   2723 C  CB    . GLU A 1 368 ? 62.65500  24.34800  55.80900  1.000 312.70000 ? 368 GLU A CB    1 
ATOM   2724 C  CG    . GLU A 1 368 ? 61.61000  24.60000  56.88300  1.000 314.42000 ? 368 GLU A CG    1 
ATOM   2725 C  CD    . GLU A 1 368 ? 60.57000  25.58800  56.42900  1.000 312.94000 ? 368 GLU A CD    1 
ATOM   2726 O  OE1   . GLU A 1 368 ? 60.23100  26.52100  57.20600  1.000 307.29000 ? 368 GLU A OE1   1 
ATOM   2727 O  OE2   . GLU A 1 368 ? 60.12500  25.43500  55.27000  1.000 312.81000 ? 368 GLU A OE2   1 
ATOM   2728 N  N     . GLU A 1 369 ? 60.52400  23.49900  53.82100  1.000 294.20000 ? 369 GLU A N     1 
ATOM   2729 C  CA    . GLU A 1 369 ? 59.15800  23.27400  53.35700  1.000 294.81000 ? 369 GLU A CA    1 
ATOM   2730 C  C     . GLU A 1 369 ? 58.94300  21.80400  52.99800  1.000 291.64000 ? 369 GLU A C     1 
ATOM   2731 O  O     . GLU A 1 369 ? 58.02900  21.15900  53.53500  1.000 289.16000 ? 369 GLU A O     1 
ATOM   2732 C  CB    . GLU A 1 369 ? 58.83700  24.22500  52.19800  1.000 299.67000 ? 369 GLU A CB    1 
ATOM   2733 C  CG    . GLU A 1 369 ? 57.76200  23.83800  51.12100  1.000 301.46000 ? 369 GLU A CG    1 
ATOM   2734 C  CD    . GLU A 1 369 ? 57.64500  24.85600  49.93800  1.000 296.05000 ? 369 GLU A CD    1 
ATOM   2735 O  OE1   . GLU A 1 369 ? 56.58500  24.85400  49.25600  1.000 293.34000 ? 369 GLU A OE1   1 
ATOM   2736 O  OE2   . GLU A 1 369 ? 58.58800  25.64100  49.68700  1.000 298.76000 ? 369 GLU A OE2   1 
ATOM   2737 N  N     . TRP A 1 370 ? 59.84400  21.21700  52.18500  1.000 299.70000 ? 370 TRP A N     1 
ATOM   2738 C  CA    . TRP A 1 370 ? 59.70200  19.79200  51.83800  1.000 300.66000 ? 370 TRP A CA    1 
ATOM   2739 C  C     . TRP A 1 370 ? 59.86800  18.88300  53.06000  1.000 294.06000 ? 370 TRP A C     1 
ATOM   2740 O  O     . TRP A 1 370 ? 59.08700  17.93300  53.22200  1.000 296.66000 ? 370 TRP A O     1 
ATOM   2741 C  CB    . TRP A 1 370 ? 60.68100  19.36600  50.70800  1.000 299.22000 ? 370 TRP A CB    1 
ATOM   2742 C  CG    . TRP A 1 370 ? 60.07300  18.39000  49.63900  1.000 287.97000 ? 370 TRP A CG    1 
ATOM   2743 C  CD1   . TRP A 1 370 ? 59.23500  18.71900  48.61000  1.000 282.44000 ? 370 TRP A CD1   1 
ATOM   2744 C  CD2   . TRP A 1 370 ? 60.28000  16.96700  49.53600  1.000 287.06000 ? 370 TRP A CD2   1 
ATOM   2745 N  NE1   . TRP A 1 370 ? 58.89500  17.59500  47.89400  1.000 282.13000 ? 370 TRP A NE1   1 
ATOM   2746 C  CE2   . TRP A 1 370 ? 59.52300  16.50800  48.44100  1.000 281.94000 ? 370 TRP A CE2   1 
ATOM   2747 C  CE3   . TRP A 1 370 ? 61.02200  16.03900  50.27300  1.000 292.08000 ? 370 TRP A CE3   1 
ATOM   2748 C  CZ2   . TRP A 1 370 ? 59.49600  15.16500  48.06400  1.000 287.86000 ? 370 TRP A CZ2   1 
ATOM   2749 C  CZ3   . TRP A 1 370 ? 60.99300  14.70600  49.89700  1.000 288.84000 ? 370 TRP A CZ3   1 
ATOM   2750 C  CH2   . TRP A 1 370 ? 60.23600  14.28200  48.80800  1.000 287.70000 ? 370 TRP A CH2   1 
ATOM   2751 N  N     . ASN A 1 371 ? 60.85700  19.13000  53.93500  1.000 291.93000 ? 371 ASN A N     1 
ATOM   2752 C  CA    . ASN A 1 371 ? 60.91600  18.25300  55.09800  1.000 288.19000 ? 371 ASN A CA    1 
ATOM   2753 C  C     . ASN A 1 371 ? 59.60700  18.34100  55.88600  1.000 291.27000 ? 371 ASN A C     1 
ATOM   2754 O  O     . ASN A 1 371 ? 59.19800  17.34700  56.51000  1.000 295.81000 ? 371 ASN A O     1 
ATOM   2755 C  CB    . ASN A 1 371 ? 62.18300  18.53600  55.93700  1.000 286.36000 ? 371 ASN A CB    1 
ATOM   2756 C  CG    . ASN A 1 371 ? 63.44900  18.02000  55.24500  1.000 292.81000 ? 371 ASN A CG    1 
ATOM   2757 O  OD1   . ASN A 1 371 ? 63.50100  17.97500  54.03000  1.000 293.29000 ? 371 ASN A OD1   1 
ATOM   2758 N  ND2   . ASN A 1 371 ? 64.45900  17.61700  56.01500  1.000 299.69000 ? 371 ASN A ND2   1 
ATOM   2759 N  N     . ALA A 1 372 ? 58.87500  19.46700  55.76000  1.000 288.79000 ? 372 ALA A N     1 
ATOM   2760 C  CA    . ALA A 1 372 ? 57.53900  19.55800  56.35300  1.000 290.71000 ? 372 ALA A CA    1 
ATOM   2761 C  C     . ALA A 1 372 ? 56.57400  18.56400  55.72900  1.000 293.33000 ? 372 ALA A C     1 
ATOM   2762 O  O     . ALA A 1 372 ? 55.83000  17.86600  56.44100  1.000 290.30000 ? 372 ALA A O     1 
ATOM   2763 C  CB    . ALA A 1 372 ? 56.98100  20.95900  56.18200  1.000 291.71000 ? 372 ALA A CB    1 
ATOM   2764 N  N     . PHE A 1 373 ? 56.53400  18.53300  54.39500  1.000 303.45000 ? 373 PHE A N     1 
ATOM   2765 C  CA    . PHE A 1 373 ? 55.79000  17.49000  53.69700  1.000 303.75000 ? 373 PHE A CA    1 
ATOM   2766 C  C     . PHE A 1 373 ? 56.23700  16.09200  54.15100  1.000 303.75000 ? 373 PHE A C     1 
ATOM   2767 O  O     . PHE A 1 373 ? 55.40100  15.27500  54.57400  1.000 299.01000 ? 373 PHE A O     1 
ATOM   2768 C  CB    . PHE A 1 373 ? 55.95400  17.68800  52.17400  1.000 307.76000 ? 373 PHE A CB    1 
ATOM   2769 C  CG    . PHE A 1 373 ? 55.21200  18.91800  51.60100  1.000 300.69000 ? 373 PHE A CG    1 
ATOM   2770 C  CD1   . PHE A 1 373 ? 53.98700  19.32600  52.11800  1.000 288.64000 ? 373 PHE A CD1   1 
ATOM   2771 C  CD2   . PHE A 1 373 ? 55.74400  19.64600  50.52300  1.000 302.51000 ? 373 PHE A CD2   1 
ATOM   2772 C  CE1   . PHE A 1 373 ? 53.31200  20.42500  51.59600  1.000 286.49000 ? 373 PHE A CE1   1 
ATOM   2773 C  CE2   . PHE A 1 373 ? 55.07100  20.75700  49.99000  1.000 293.02000 ? 373 PHE A CE2   1 
ATOM   2774 C  CZ    . PHE A 1 373 ? 53.85100  21.14600  50.53100  1.000 292.45000 ? 373 PHE A CZ    1 
ATOM   2775 N  N     . ASN A 1 374 ? 57.56300  15.84400  54.14100  1.000 296.15000 ? 374 ASN A N     1 
ATOM   2776 C  CA    . ASN A 1 374 ? 58.14600  14.54100  54.48900  1.000 288.74000 ? 374 ASN A CA    1 
ATOM   2777 C  C     . ASN A 1 374 ? 57.51000  13.95100  55.73300  1.000 285.26000 ? 374 ASN A C     1 
ATOM   2778 O  O     . ASN A 1 374 ? 57.01900  12.81200  55.72700  1.000 287.59000 ? 374 ASN A O     1 
ATOM   2779 C  CB    . ASN A 1 374 ? 59.64300  14.69400  54.73000  1.000 280.18000 ? 374 ASN A CB    1 
ATOM   2780 C  CG    . ASN A 1 374 ? 60.47000  13.64100  54.02500  1.000 294.43000 ? 374 ASN A CG    1 
ATOM   2781 O  OD1   . ASN A 1 374 ? 59.94500  12.72400  53.40100  1.000 297.42000 ? 374 ASN A OD1   1 
ATOM   2782 N  ND2   . ASN A 1 374 ? 61.78500  13.77100  54.13000  1.000 303.51000 ? 374 ASN A ND2   1 
ATOM   2783 N  N     . GLU A 1 375 ? 57.50200  14.72500  56.81400  1.000 298.72000 ? 375 GLU A N     1 
ATOM   2784 C  CA    . GLU A 1 375 ? 56.95900  14.21400  58.06300  1.000 300.79000 ? 375 GLU A CA    1 
ATOM   2785 C  C     . GLU A 1 375 ? 55.50400  13.78400  57.90600  1.000 287.59000 ? 375 GLU A C     1 
ATOM   2786 O  O     . GLU A 1 375 ? 55.13100  12.68600  58.32700  1.000 293.99000 ? 375 GLU A O     1 
ATOM   2787 C  CB    . GLU A 1 375 ? 57.11300  15.27300  59.16100  1.000 310.32000 ? 375 GLU A CB    1 
ATOM   2788 C  CG    . GLU A 1 375 ? 58.03700  14.88800  60.37100  1.000 313.81000 ? 375 GLU A CG    1 
ATOM   2789 C  CD    . GLU A 1 375 ? 59.52500  15.27300  60.22500  1.000 326.49000 ? 375 GLU A CD    1 
ATOM   2790 O  OE1   . GLU A 1 375 ? 60.35100  14.36900  59.95600  1.000 343.02000 ? 375 GLU A OE1   1 
ATOM   2791 O  OE2   . GLU A 1 375 ? 59.87600  16.46500  60.40900  1.000 325.92000 ? 375 GLU A OE2   1 
ATOM   2792 N  N     . VAL A 1 376 ? 54.67800  14.60300  57.25800  1.000 275.78000 ? 376 VAL A N     1 
ATOM   2793 C  CA    . VAL A 1 376 ? 53.24900  14.30200  57.22500  1.000 269.68000 ? 376 VAL A CA    1 
ATOM   2794 C  C     . VAL A 1 376 ? 52.99700  12.98700  56.53500  1.000 273.91000 ? 376 VAL A C     1 
ATOM   2795 O  O     . VAL A 1 376 ? 51.99700  12.30800  56.79700  1.000 277.10000 ? 376 VAL A O     1 
ATOM   2796 C  CB    . VAL A 1 376 ? 52.47500  15.42300  56.53300  1.000 265.24000 ? 376 VAL A CB    1 
ATOM   2797 C  CG1   . VAL A 1 376 ? 51.05300  15.36300  56.96200  1.000 256.22000 ? 376 VAL A CG1   1 
ATOM   2798 C  CG2   . VAL A 1 376 ? 53.09600  16.70400  56.84900  1.000 273.13000 ? 376 VAL A CG2   1 
ATOM   2799 N  N     . THR A 1 377 ? 53.94100  12.58000  55.72500  1.000 281.85000 ? 377 THR A N     1 
ATOM   2800 C  CA    . THR A 1 377 ? 53.71400  11.53200  54.77700  1.000 284.95000 ? 377 THR A CA    1 
ATOM   2801 C  C     . THR A 1 377 ? 53.84800  10.16700  55.42600  1.000 283.15000 ? 377 THR A C     1 
ATOM   2802 O  O     . THR A 1 377 ? 54.65300  9.99200   56.35600  1.000 287.04000 ? 377 THR A O     1 
ATOM   2803 C  CB    . THR A 1 377 ? 54.67400  11.71800  53.63200  1.000 301.27000 ? 377 THR A CB    1 
ATOM   2804 O  OG1   . THR A 1 377 ? 54.42800  13.02500  53.11700  1.000 306.17000 ? 377 THR A OG1   1 
ATOM   2805 C  CG2   . THR A 1 377 ? 54.45700  10.70200  52.54200  1.000 306.03000 ? 377 THR A CG2   1 
ATOM   2806 N  N     . PRO A 1 378 ? 53.00300  9.21600   55.01700  1.000 289.01000 ? 378 PRO A N     1 
ATOM   2807 C  CA    . PRO A 1 378 ? 53.18600  7.81700   55.40800  1.000 294.68000 ? 378 PRO A CA    1 
ATOM   2808 C  C     . PRO A 1 378 ? 54.56400  7.33000   55.01500  1.000 293.51000 ? 378 PRO A C     1 
ATOM   2809 O  O     . PRO A 1 378 ? 55.24600  7.94200   54.19500  1.000 296.49000 ? 378 PRO A O     1 
ATOM   2810 C  CB    . PRO A 1 378 ? 52.11000  7.07100   54.62500  1.000 289.94000 ? 378 PRO A CB    1 
ATOM   2811 C  CG    . PRO A 1 378 ? 51.08700  8.11000   54.31300  1.000 288.11000 ? 378 PRO A CG    1 
ATOM   2812 C  CD    . PRO A 1 378 ? 51.71000  9.46200   54.33600  1.000 290.90000 ? 378 PRO A CD    1 
ATOM   2813 N  N     . LYS A 1 379 ? 54.99300  6.23600   55.65300  1.000 300.06000 ? 379 LYS A N     1 
ATOM   2814 C  CA    . LYS A 1 379 ? 56.40300  5.84600   55.56500  1.000 305.28000 ? 379 LYS A CA    1 
ATOM   2815 C  C     . LYS A 1 379 ? 56.77700  5.34300   54.17900  1.000 301.16000 ? 379 LYS A C     1 
ATOM   2816 O  O     . LYS A 1 379 ? 57.88200  5.61100   53.68600  1.000 309.58000 ? 379 LYS A O     1 
ATOM   2817 C  CB    . LYS A 1 379 ? 56.71900  4.76200   56.56700  1.000 316.02000 ? 379 LYS A CB    1 
ATOM   2818 C  CG    . LYS A 1 379 ? 55.70300  4.68300   57.68700  1.000 321.78000 ? 379 LYS A CG    1 
ATOM   2819 C  CD    . LYS A 1 379 ? 56.15200  3.77100   58.83000  1.000 338.12000 ? 379 LYS A CD    1 
ATOM   2820 C  CE    . LYS A 1 379 ? 56.29400  4.57100   60.13600  1.000 331.68000 ? 379 LYS A CE    1 
ATOM   2821 N  NZ    . LYS A 1 379 ? 56.23800  3.70500   61.34600  1.000 322.96000 ? 379 LYS A NZ    1 
ATOM   2822 N  N     . ASN A 1 380 ? 55.88700  4.58600   53.54300  1.000 304.36000 ? 380 ASN A N     1 
ATOM   2823 C  CA    . ASN A 1 380 ? 56.20400  3.94700   52.27200  1.000 316.93000 ? 380 ASN A CA    1 
ATOM   2824 C  C     . ASN A 1 380 ? 55.66700  4.69700   51.04700  1.000 314.50000 ? 380 ASN A C     1 
ATOM   2825 O  O     . ASN A 1 380 ? 56.05200  4.35200   49.91300  1.000 310.36000 ? 380 ASN A O     1 
ATOM   2826 C  CB    . ASN A 1 380 ? 55.69100  2.49400   52.28200  1.000 318.16000 ? 380 ASN A CB    1 
ATOM   2827 C  CG    . ASN A 1 380 ? 54.26600  2.38400   52.80300  1.000 304.79000 ? 380 ASN A CG    1 
ATOM   2828 O  OD1   . ASN A 1 380 ? 53.37600  3.09600   52.33500  1.000 304.00000 ? 380 ASN A OD1   1 
ATOM   2829 N  ND2   . ASN A 1 380 ? 54.04300  1.51200   53.77800  1.000 310.84000 ? 380 ASN A ND2   1 
ATOM   2830 N  N     . THR A 1 381 ? 54.80600  5.70600   51.23600  1.000 315.13000 ? 381 THR A N     1 
ATOM   2831 C  CA    . THR A 1 381 ? 54.42500  6.56700   50.12500  1.000 303.09000 ? 381 THR A CA    1 
ATOM   2832 C  C     . THR A 1 381 ? 55.63500  7.36200   49.66400  1.000 291.07000 ? 381 THR A C     1 
ATOM   2833 O  O     . THR A 1 381 ? 56.37300  7.93800   50.46500  1.000 290.82000 ? 381 THR A O     1 
ATOM   2834 C  CB    . THR A 1 381 ? 53.30600  7.53200   50.53000  1.000 297.72000 ? 381 THR A CB    1 
ATOM   2835 O  OG1   . THR A 1 381 ? 52.05000  6.84500   50.59900  1.000 287.79000 ? 381 THR A OG1   1 
ATOM   2836 C  CG2   . THR A 1 381 ? 53.20400  8.69300   49.51700  1.000 289.43000 ? 381 THR A CG2   1 
ATOM   2837 N  N     . ASN A 1 382 ? 55.84400  7.41000   48.37200  1.000 286.42000 ? 382 ASN A N     1 
ATOM   2838 C  CA    . ASN A 1 382 ? 56.90500  8.23600   47.83800  1.000 288.37000 ? 382 ASN A CA    1 
ATOM   2839 C  C     . ASN A 1 382 ? 56.34700  9.62600   47.56300  1.000 286.95000 ? 382 ASN A C     1 
ATOM   2840 O  O     . ASN A 1 382 ? 55.29700  9.76500   46.92500  1.000 288.52000 ? 382 ASN A O     1 
ATOM   2841 C  CB    . ASN A 1 382 ? 57.48700  7.61400   46.57900  1.000 299.24000 ? 382 ASN A CB    1 
ATOM   2842 C  CG    . ASN A 1 382 ? 58.70200  8.35800   46.10200  1.000 311.85000 ? 382 ASN A CG    1 
ATOM   2843 O  OD1   . ASN A 1 382 ? 59.37200  9.04300   46.89100  1.000 312.00000 ? 382 ASN A OD1   1 
ATOM   2844 N  ND2   . ASN A 1 382 ? 58.99700  8.25000   44.80700  1.000 315.93000 ? 382 ASN A ND2   1 
ATOM   2845 N  N     . LEU A 1 383 ? 57.03400  10.64700  48.05700  1.000 280.14000 ? 383 LEU A N     1 
ATOM   2846 C  CA    . LEU A 1 383 ? 56.66800  12.02900  47.77800  1.000 278.86000 ? 383 LEU A CA    1 
ATOM   2847 C  C     . LEU A 1 383 ? 57.62300  12.58200  46.73100  1.000 282.39000 ? 383 LEU A C     1 
ATOM   2848 O  O     . LEU A 1 383 ? 58.84100  12.50600  46.92200  1.000 283.42000 ? 383 LEU A O     1 
ATOM   2849 C  CB    . LEU A 1 383 ? 56.71800  12.88300  49.03700  1.000 276.50000 ? 383 LEU A CB    1 
ATOM   2850 C  CG    . LEU A 1 383 ? 56.13500  14.26000  48.77300  1.000 279.47000 ? 383 LEU A CG    1 
ATOM   2851 C  CD1   . LEU A 1 383 ? 54.69200  14.15800  48.30700  1.000 281.62000 ? 383 LEU A CD1   1 
ATOM   2852 C  CD2   . LEU A 1 383 ? 56.22100  15.05800  50.02600  1.000 283.93000 ? 383 LEU A CD2   1 
ATOM   2853 N  N     . VAL A 1 384 ? 57.08600  13.12200  45.62800  1.000 281.56000 ? 384 VAL A N     1 
ATOM   2854 C  CA    . VAL A 1 384 ? 57.91600  13.68300  44.57100  1.000 276.12000 ? 384 VAL A CA    1 
ATOM   2855 C  C     . VAL A 1 384 ? 57.54600  15.14600  44.33800  1.000 278.70000 ? 384 VAL A C     1 
ATOM   2856 O  O     . VAL A 1 384 ? 56.35400  15.43000  44.08400  1.000 277.78000 ? 384 VAL A O     1 
ATOM   2857 C  CB    . VAL A 1 384 ? 57.81200  12.88400  43.26800  1.000 270.29000 ? 384 VAL A CB    1 
ATOM   2858 C  CG1   . VAL A 1 384 ? 58.76800  13.46300  42.23100  1.000 269.84000 ? 384 VAL A CG1   1 
ATOM   2859 C  CG2   . VAL A 1 384 ? 58.06300  11.42200  43.52400  1.000 276.36000 ? 384 VAL A CG2   1 
ATOM   2860 N  N     . GLY A 1 385 ? 58.50200  16.00600  44.42900  1.000 278.79000 ? 385 GLY A N     1 
ATOM   2861 C  CA    . GLY A 1 385 ? 58.35000  17.41400  44.06700  1.000 278.41000 ? 385 GLY A CA    1 
ATOM   2862 C  C     . GLY A 1 385 ? 58.81900  17.58900  42.68300  1.000 271.12000 ? 385 GLY A C     1 
ATOM   2863 O  O     . GLY A 1 385 ? 59.86400  17.05600  42.26500  1.000 269.00000 ? 385 GLY A O     1 
ATOM   2864 N  N     . VAL A 1 386 ? 58.03300  18.30800  41.87100  1.000 265.94000 ? 386 VAL A N     1 
ATOM   2865 C  CA    . VAL A 1 386 ? 58.32100  18.49800  40.47400  1.000 265.31000 ? 386 VAL A CA    1 
ATOM   2866 C  C     . VAL A 1 386 ? 58.10300  19.95900  40.13100  1.000 266.54000 ? 386 VAL A C     1 
ATOM   2867 O  O     . VAL A 1 386 ? 57.00800  20.49100  40.33100  1.000 262.72000 ? 386 VAL A O     1 
ATOM   2868 C  CB    . VAL A 1 386 ? 57.46300  17.60300  39.58000  1.000 257.60000 ? 386 VAL A CB    1 
ATOM   2869 C  CG1   . VAL A 1 386 ? 58.19900  17.36300  38.28700  1.000 268.41000 ? 386 VAL A CG1   1 
ATOM   2870 C  CG2   . VAL A 1 386 ? 57.15200  16.29400  40.26200  1.000 260.92000 ? 386 VAL A CG2   1 
ATOM   2871 N  N     . THR A 1 387 ? 59.13000  20.59300  39.58300  1.000 269.56000 ? 387 THR A N     1 
ATOM   2872 C  CA    . THR A 1 387 ? 59.10200  22.00200  39.20400  1.000 275.91000 ? 387 THR A CA    1 
ATOM   2873 C  C     . THR A 1 387 ? 58.94300  22.06700  37.68900  1.000 275.48000 ? 387 THR A C     1 
ATOM   2874 O  O     . THR A 1 387 ? 59.85600  21.71100  36.93600  1.000 279.04000 ? 387 THR A O     1 
ATOM   2875 C  CB    . THR A 1 387 ? 60.36700  22.73400  39.64900  1.000 290.40000 ? 387 THR A CB    1 
ATOM   2876 O  OG1   . THR A 1 387 ? 60.25600  23.08300  41.03200  1.000 302.01000 ? 387 THR A OG1   1 
ATOM   2877 C  CG2   . THR A 1 387 ? 60.55900  24.00900  38.83700  1.000 288.34000 ? 387 THR A CG2   1 
ATOM   2878 N  N     . ILE A 1 388 ? 57.79000  22.52300  37.23900  1.000 272.80000 ? 388 ILE A N     1 
ATOM   2879 C  CA    . ILE A 1 388 ? 57.52100  22.67600  35.82000  1.000 274.30000 ? 388 ILE A CA    1 
ATOM   2880 C  C     . ILE A 1 388 ? 57.73800  24.14200  35.50800  1.000 276.27000 ? 388 ILE A C     1 
ATOM   2881 O  O     . ILE A 1 388 ? 56.86200  24.97700  35.75200  1.000 278.46000 ? 388 ILE A O     1 
ATOM   2882 C  CB    . ILE A 1 388 ? 56.11400  22.22300  35.46800  1.000 272.23000 ? 388 ILE A CB    1 
ATOM   2883 C  CG1   . ILE A 1 388 ? 56.02100  20.75100  35.78500  1.000 284.53000 ? 388 ILE A CG1   1 
ATOM   2884 C  CG2   . ILE A 1 388 ? 55.79800  22.54200  34.02500  1.000 272.05000 ? 388 ILE A CG2   1 
ATOM   2885 C  CD1   . ILE A 1 388 ? 54.63600  20.21700  35.69400  1.000 292.49000 ? 388 ILE A CD1   1 
ATOM   2886 N  N     . THR A 1 389 ? 58.92400  24.48400  35.01700  1.000 277.27000 ? 389 THR A N     1 
ATOM   2887 C  CA    . THR A 1 389 ? 59.17200  25.86500  34.62400  1.000 284.64000 ? 389 THR A CA    1 
ATOM   2888 C  C     . THR A 1 389 ? 59.14800  25.95900  33.11300  1.000 293.04000 ? 389 THR A C     1 
ATOM   2889 O  O     . THR A 1 389 ? 59.96400  25.31400  32.44700  1.000 295.01000 ? 389 THR A O     1 
ATOM   2890 C  CB    . THR A 1 389 ? 60.50000  26.41100  35.13700  1.000 280.69000 ? 389 THR A CB    1 
ATOM   2891 O  OG1   . THR A 1 389 ? 60.76500  27.66400  34.48000  1.000 287.95000 ? 389 THR A OG1   1 
ATOM   2892 C  CG2   . THR A 1 389 ? 61.61100  25.43300  34.89300  1.000 280.85000 ? 389 THR A CG2   1 
ATOM   2893 N  N     . LYS A 1 390 ? 58.22200  26.77100  32.58400  1.000 302.60000 ? 390 LYS A N     1 
ATOM   2894 C  CA    . LYS A 1 390 ? 58.29400  27.30800  31.22600  1.000 311.30000 ? 390 LYS A CA    1 
ATOM   2895 C  C     . LYS A 1 390 ? 59.21200  28.52100  31.27500  1.000 310.63000 ? 390 LYS A C     1 
ATOM   2896 O  O     . LYS A 1 390 ? 58.77400  29.64500  31.05500  1.000 310.94000 ? 390 LYS A O     1 
ATOM   2897 C  CB    . LYS A 1 390 ? 56.92700  27.72600  30.67400  1.000 308.19000 ? 390 LYS A CB    1 
ATOM   2898 C  CG    . LYS A 1 390 ? 55.76100  26.79800  31.01800  1.000 307.05000 ? 390 LYS A CG    1 
ATOM   2899 C  CD    . LYS A 1 390 ? 54.73500  26.77800  29.87100  1.000 305.35000 ? 390 LYS A CD    1 
ATOM   2900 C  CE    . LYS A 1 390 ? 53.54600  25.91500  30.21300  1.000 303.22000 ? 390 LYS A CE    1 
ATOM   2901 N  NZ    . LYS A 1 390 ? 53.56800  24.80800  29.32600  1.000 298.66000 ? 390 LYS A NZ    1 
ATOM   2902 N  N     . SER A 1 391 ? 60.49500  28.30400  31.53100  1.000 300.69000 ? 391 SER A N     1 
ATOM   2903 C  CA    . SER A 1 391 ? 61.50200  29.26000  31.09800  1.000 300.78000 ? 391 SER A CA    1 
ATOM   2904 C  C     . SER A 1 391 ? 61.45300  29.29600  29.57000  1.000 304.26000 ? 391 SER A C     1 
ATOM   2905 O  O     . SER A 1 391 ? 60.54800  28.72300  28.95800  1.000 306.31000 ? 391 SER A O     1 
ATOM   2906 C  CB    . SER A 1 391 ? 62.87400  28.85900  31.66200  1.000 294.79000 ? 391 SER A CB    1 
ATOM   2907 O  OG    . SER A 1 391 ? 62.89200  29.11600  33.07200  1.000 282.89000 ? 391 SER A OG    1 
ATOM   2908 N  N     . LYS A 1 392 ? 62.44900  29.91100  28.94700  1.000 292.67000 ? 392 LYS A N     1 
ATOM   2909 C  CA    . LYS A 1 392 ? 62.53100  29.99800  27.48300  1.000 291.51000 ? 392 LYS A CA    1 
ATOM   2910 C  C     . LYS A 1 392 ? 63.79400  29.28100  27.01100  1.000 276.30000 ? 392 LYS A C     1 
ATOM   2911 O  O     . LYS A 1 392 ? 64.76200  29.90300  26.55900  1.000 282.34000 ? 392 LYS A O     1 
ATOM   2912 C  CB    . LYS A 1 392 ? 62.54500  31.44600  27.03500  1.000 304.24000 ? 392 LYS A CB    1 
ATOM   2913 N  N     . PRO A 1 393 ? 63.85400  27.99900  27.18300  1.000 291.31000 ? 393 PRO A N     1 
ATOM   2914 C  CA    . PRO A 1 393 ? 65.05900  27.25000  26.86000  1.000 294.01000 ? 393 PRO A CA    1 
ATOM   2915 C  C     . PRO A 1 393 ? 64.79000  26.31000  25.69300  1.000 291.86000 ? 393 PRO A C     1 
ATOM   2916 O  O     . PRO A 1 393 ? 63.63100  25.94700  25.44300  1.000 295.11000 ? 393 PRO A O     1 
ATOM   2917 C  CB    . PRO A 1 393 ? 65.31700  26.49900  28.17700  1.000 299.88000 ? 393 PRO A CB    1 
ATOM   2918 C  CG    . PRO A 1 393 ? 63.86800  26.46800  28.89400  1.000 300.47000 ? 393 PRO A CG    1 
ATOM   2919 C  CD    . PRO A 1 393 ? 62.93200  27.14500  27.91100  1.000 300.91000 ? 393 PRO A CD    1 
ATOM   2920 N  N     . LEU A 1 394 ? 65.82100  25.96600  24.93800  1.000 297.16000 ? 394 LEU A N     1 
ATOM   2921 C  CA    . LEU A 1 394 ? 65.76800  24.79800  24.07400  1.000 295.57000 ? 394 LEU A CA    1 
ATOM   2922 C  C     . LEU A 1 394 ? 64.56900  24.82400  23.12000  1.000 282.76000 ? 394 LEU A C     1 
ATOM   2923 O  O     . LEU A 1 394 ? 63.89700  23.80500  22.88500  1.000 278.32000 ? 394 LEU A O     1 
ATOM   2924 C  CB    . LEU A 1 394 ? 65.73900  23.50400  24.89700  1.000 303.55000 ? 394 LEU A CB    1 
ATOM   2925 C  CG    . LEU A 1 394 ? 67.01500  22.63900  24.85400  1.000 302.31000 ? 394 LEU A CG    1 
ATOM   2926 C  CD1   . LEU A 1 394 ? 66.61700  21.19000  24.91100  1.000 299.26000 ? 394 LEU A CD1   1 
ATOM   2927 C  CD2   . LEU A 1 394 ? 67.84100  22.92300  23.61500  1.000 298.48000 ? 394 LEU A CD2   1 
ATOM   2928 N  N     . LYS A 1 395 ? 64.24600  26.01000  22.62800  1.000 283.63000 ? 395 LYS A N     1 
ATOM   2929 C  CA    . LYS A 1 395 ? 63.36600  26.07600  21.48100  1.000 278.55000 ? 395 LYS A CA    1 
ATOM   2930 C  C     . LYS A 1 395 ? 64.00400  25.22000  20.39700  1.000 276.42000 ? 395 LYS A C     1 
ATOM   2931 O  O     . LYS A 1 395 ? 65.13400  25.48600  19.97000  1.000 276.76000 ? 395 LYS A O     1 
ATOM   2932 C  CB    . LYS A 1 395 ? 63.16900  27.52600  21.04300  1.000 287.70000 ? 395 LYS A CB    1 
ATOM   2933 C  CG    . LYS A 1 395 ? 61.69900  27.89100  20.75800  1.000 289.48000 ? 395 LYS A CG    1 
ATOM   2934 C  CD    . LYS A 1 395 ? 61.32000  29.27400  21.31600  1.000 292.57000 ? 395 LYS A CD    1 
ATOM   2935 C  CE    . LYS A 1 395 ? 62.01600  30.43300  20.62000  1.000 295.23000 ? 395 LYS A CE    1 
ATOM   2936 N  NZ    . LYS A 1 395 ? 61.84300  31.71300  21.36800  1.000 295.18000 ? 395 LYS A NZ    1 
ATOM   2937 N  N     . LEU A 1 396 ? 63.30600  24.16000  19.99300  1.000 271.84000 ? 396 LEU A N     1 
ATOM   2938 C  CA    . LEU A 1 396 ? 63.83700  23.18000  19.05500  1.000 269.22000 ? 396 LEU A CA    1 
ATOM   2939 C  C     . LEU A 1 396 ? 63.19100  23.34100  17.69200  1.000 270.38000 ? 396 LEU A C     1 
ATOM   2940 O  O     . LEU A 1 396 ? 61.98400  23.13400  17.54500  1.000 271.54000 ? 396 LEU A O     1 
ATOM   2941 C  CB    . LEU A 1 396 ? 63.61500  21.77000  19.55300  1.000 266.84000 ? 396 LEU A CB    1 
ATOM   2942 C  CG    . LEU A 1 396 ? 64.86400  21.25500  20.21500  1.000 267.24000 ? 396 LEU A CG    1 
ATOM   2943 C  CD1   . LEU A 1 396 ? 64.87300  19.75600  20.18500  1.000 274.68000 ? 396 LEU A CD1   1 
ATOM   2944 C  CD2   . LEU A 1 396 ? 66.08300  21.81200  19.51000  1.000 272.04000 ? 396 LEU A CD2   1 
ATOM   2945 N  N     . TYR A 1 397 ? 64.00900  23.65700  16.69500  1.000 279.96000 ? 397 TYR A N     1 
ATOM   2946 C  CA    . TYR A 1 397 ? 63.57700  23.91800  15.32700  1.000 278.75000 ? 397 TYR A CA    1 
ATOM   2947 C  C     . TYR A 1 397 ? 63.84300  22.67700  14.47800  1.000 282.97000 ? 397 TYR A C     1 
ATOM   2948 O  O     . TYR A 1 397 ? 65.00600  22.30700  14.27700  1.000 289.21000 ? 397 TYR A O     1 
ATOM   2949 C  CB    . TYR A 1 397 ? 64.32100  25.12600  14.73700  1.000 282.92000 ? 397 TYR A CB    1 
ATOM   2950 C  CG    . TYR A 1 397 ? 64.25100  26.45900  15.49800  1.000 291.45000 ? 397 TYR A CG    1 
ATOM   2951 C  CD1   . TYR A 1 397 ? 63.09600  27.24400  15.46800  1.000 302.23000 ? 397 TYR A CD1   1 
ATOM   2952 C  CD2   . TYR A 1 397 ? 65.35200  26.96200  16.20300  1.000 288.26000 ? 397 TYR A CD2   1 
ATOM   2953 C  CE1   . TYR A 1 397 ? 63.01900  28.48200  16.14700  1.000 305.97000 ? 397 TYR A CE1   1 
ATOM   2954 C  CE2   . TYR A 1 397 ? 65.27600  28.19700  16.89200  1.000 289.51000 ? 397 TYR A CE2   1 
ATOM   2955 C  CZ    . TYR A 1 397 ? 64.11800  28.96100  16.84900  1.000 295.90000 ? 397 TYR A CZ    1 
ATOM   2956 O  OH    . TYR A 1 397 ? 64.04700  30.18200  17.51400  1.000 285.75000 ? 397 TYR A OH    1 
ATOM   2957 N  N     . LYS A 1 398 ? 62.77800  22.01800  14.01000  1.000 275.03000 ? 398 LYS A N     1 
ATOM   2958 C  CA    . LYS A 1 398 ? 62.95800  20.87100  13.12700  1.000 278.13000 ? 398 LYS A CA    1 
ATOM   2959 C  C     . LYS A 1 398 ? 63.74400  21.28200  11.88500  1.000 281.18000 ? 398 LYS A C     1 
ATOM   2960 O  O     . LYS A 1 398 ? 63.55600  22.38000  11.35700  1.000 285.74000 ? 398 LYS A O     1 
ATOM   2961 C  CB    . LYS A 1 398 ? 61.59400  20.30000  12.73600  1.000 289.24000 ? 398 LYS A CB    1 
ATOM   2962 C  CG    . LYS A 1 398 ? 61.61700  18.89900  12.07600  1.000 298.48000 ? 398 LYS A CG    1 
ATOM   2963 C  CD    . LYS A 1 398 ? 60.19200  18.35400  11.82500  1.000 303.01000 ? 398 LYS A CD    1 
ATOM   2964 C  CE    . LYS A 1 398 ? 59.48800  19.16700  10.74200  1.000 292.34000 ? 398 LYS A CE    1 
ATOM   2965 N  NZ    . LYS A 1 398 ? 59.07000  18.45900  9.49900   1.000 282.31000 ? 398 LYS A NZ    1 
ATOM   2966 N  N     . THR A 1 399 ? 64.63600  20.40400  11.41600  1.000 271.29000 ? 399 THR A N     1 
ATOM   2967 C  CA    . THR A 1 399 ? 65.52700  20.82600  10.33800  1.000 272.64000 ? 399 THR A CA    1 
ATOM   2968 C  C     . THR A 1 399 ? 64.77100  20.99900  9.03200   1.000 276.63000 ? 399 THR A C     1 
ATOM   2969 O  O     . THR A 1 399 ? 64.95200  21.99300  8.32100   1.000 278.65000 ? 399 THR A O     1 
ATOM   2970 C  CB    . THR A 1 399 ? 66.65500  19.83800  10.14300  1.000 275.12000 ? 399 THR A CB    1 
ATOM   2971 O  OG1   . THR A 1 399 ? 66.65700  18.90100  11.21500  1.000 280.20000 ? 399 THR A OG1   1 
ATOM   2972 C  CG2   . THR A 1 399 ? 67.99100  20.55800  10.14400  1.000 279.67000 ? 399 THR A CG2   1 
ATOM   2973 N  N     . GLU A 1 400 ? 63.89400  20.06600  8.71100   1.000 274.58000 ? 400 GLU A N     1 
ATOM   2974 C  CA    . GLU A 1 400 ? 63.26400  20.03200  7.40200   1.000 278.23000 ? 400 GLU A CA    1 
ATOM   2975 C  C     . GLU A 1 400 ? 61.75300  20.10200  7.49600   1.000 272.53000 ? 400 GLU A C     1 
ATOM   2976 O  O     . GLU A 1 400 ? 61.13300  19.27100  8.16200   1.000 274.45000 ? 400 GLU A O     1 
ATOM   2977 C  CB    . GLU A 1 400 ? 63.66000  18.76900  6.68800   1.000 289.80000 ? 400 GLU A CB    1 
ATOM   2978 C  CG    . GLU A 1 400 ? 64.26700  19.05500  5.38700   1.000 301.62000 ? 400 GLU A CG    1 
ATOM   2979 C  CD    . GLU A 1 400 ? 64.12000  17.88600  4.49100   1.000 310.20000 ? 400 GLU A CD    1 
ATOM   2980 O  OE1   . GLU A 1 400 ? 64.78300  16.86200  4.75800   1.000 325.24000 ? 400 GLU A OE1   1 
ATOM   2981 O  OE2   . GLU A 1 400 ? 63.29800  17.97300  3.55700   1.000 315.77000 ? 400 GLU A OE2   1 
ATOM   2982 N  N     . GLY A 1 401 ? 61.16900  21.05900  6.79900   1.000 278.34000 ? 401 GLY A N     1 
ATOM   2983 C  CA    . GLY A 1 401 ? 59.72800  21.11900  6.75300   1.000 275.66000 ? 401 GLY A CA    1 
ATOM   2984 C  C     . GLY A 1 401 ? 59.17900  22.29400  7.53200   1.000 266.39000 ? 401 GLY A C     1 
ATOM   2985 O  O     . GLY A 1 401 ? 59.87600  22.95100  8.30500   1.000 263.80000 ? 401 GLY A O     1 
ATOM   2986 N  N     . ALA A 1 402 ? 57.89100  22.56500  7.30300   1.000 272.33000 ? 402 ALA A N     1 
ATOM   2987 C  CA    . ALA A 1 402 ? 57.30300  23.80000  7.80300   1.000 276.83000 ? 402 ALA A CA    1 
ATOM   2988 C  C     . ALA A 1 402 ? 56.77100  23.59800  9.19800   1.000 279.27000 ? 402 ALA A C     1 
ATOM   2989 O  O     . ALA A 1 402 ? 56.52500  24.56600  9.92500   1.000 280.80000 ? 402 ALA A O     1 
ATOM   2990 C  CB    . ALA A 1 402 ? 56.16900  24.27100  6.89700   1.000 287.29000 ? 402 ALA A CB    1 
ATOM   2991 N  N     . PHE A 1 403 ? 56.57400  22.35700  9.57500   1.000 277.43000 ? 403 PHE A N     1 
ATOM   2992 C  CA    . PHE A 1 403 ? 55.96800  22.09600  10.83200  1.000 274.29000 ? 403 PHE A CA    1 
ATOM   2993 C  C     . PHE A 1 403 ? 57.03000  21.86500  11.87400  1.000 277.41000 ? 403 PHE A C     1 
ATOM   2994 O  O     . PHE A 1 403 ? 58.18000  21.57700  11.54500  1.000 282.11000 ? 403 PHE A O     1 
ATOM   2995 C  CB    . PHE A 1 403 ? 55.03900  20.91100  10.65700  1.000 275.56000 ? 403 PHE A CB    1 
ATOM   2996 C  CG    . PHE A 1 403 ? 53.79200  21.30700  9.99200   1.000 276.39000 ? 403 PHE A CG    1 
ATOM   2997 C  CD1   . PHE A 1 403 ? 53.57600  20.98600  8.68000   1.000 276.03000 ? 403 PHE A CD1   1 
ATOM   2998 C  CD2   . PHE A 1 403 ? 52.89800  22.12800  10.64200  1.000 287.49000 ? 403 PHE A CD2   1 
ATOM   2999 C  CE1   . PHE A 1 403 ? 52.43800  21.40000  8.03900   1.000 280.88000 ? 403 PHE A CE1   1 
ATOM   3000 C  CE2   . PHE A 1 403 ? 51.74400  22.55400  10.00600  1.000 298.29000 ? 403 PHE A CE2   1 
ATOM   3001 C  CZ    . PHE A 1 403 ? 51.50800  22.18600  8.69000   1.000 291.53000 ? 403 PHE A CZ    1 
ATOM   3002 N  N     . PRO A 1 404 ? 56.68700  22.04900  13.13100  1.000 278.02000 ? 404 PRO A N     1 
ATOM   3003 C  CA    . PRO A 1 404 ? 57.68300  21.89200  14.19000  1.000 275.52000 ? 404 PRO A CA    1 
ATOM   3004 C  C     . PRO A 1 404 ? 57.67400  20.48700  14.71000  1.000 273.15000 ? 404 PRO A C     1 
ATOM   3005 O  O     . PRO A 1 404 ? 56.80400  19.69300  14.33500  1.000 274.04000 ? 404 PRO A O     1 
ATOM   3006 C  CB    . PRO A 1 404 ? 57.23800  22.88500  15.26800  1.000 276.71000 ? 404 PRO A CB    1 
ATOM   3007 C  CG    . PRO A 1 404 ? 55.78300  23.13400  14.97300  1.000 277.40000 ? 404 PRO A CG    1 
ATOM   3008 C  CD    . PRO A 1 404 ? 55.38000  22.44100  13.67400  1.000 277.77000 ? 404 PRO A CD    1 
ATOM   3009 N  N     . ILE A 1 405 ? 58.68900  20.17800  15.52700  1.000 272.42000 ? 405 ILE A N     1 
ATOM   3010 C  CA    . ILE A 1 405 ? 58.74400  18.90400  16.23700  1.000 271.38000 ? 405 ILE A CA    1 
ATOM   3011 C  C     . ILE A 1 405 ? 57.36000  18.55600  16.73200  1.000 271.24000 ? 405 ILE A C     1 
ATOM   3012 O  O     . ILE A 1 405 ? 56.57400  19.44300  17.10600  1.000 272.89000 ? 405 ILE A O     1 
ATOM   3013 C  CB    . ILE A 1 405 ? 59.75500  18.96600  17.39300  1.000 270.99000 ? 405 ILE A CB    1 
ATOM   3014 C  CG1   . ILE A 1 405 ? 59.70000  20.37200  18.06900  1.000 278.73000 ? 405 ILE A CG1   1 
ATOM   3015 C  CG2   . ILE A 1 405 ? 61.07200  18.84900  16.82500  1.000 271.62000 ? 405 ILE A CG2   1 
ATOM   3016 C  CD1   . ILE A 1 405 ? 60.50300  20.69500  19.43600  1.000 286.85000 ? 405 ILE A CD1   1 
ATOM   3017 N  N     . MET A 1 406 ? 57.01400  17.28000  16.62300  1.000 270.08000 ? 406 MET A N     1 
ATOM   3018 C  CA    . MET A 1 406 ? 55.73700  16.86700  17.16000  1.000 271.26000 ? 406 MET A CA    1 
ATOM   3019 C  C     . MET A 1 406 ? 55.82600  16.68100  18.66300  1.000 269.31000 ? 406 MET A C     1 
ATOM   3020 O  O     . MET A 1 406 ? 56.89900  16.44600  19.22600  1.000 272.46000 ? 406 MET A O     1 
ATOM   3021 C  CB    . MET A 1 406 ? 55.27400  15.58400  16.51100  1.000 276.40000 ? 406 MET A CB    1 
ATOM   3022 C  CG    . MET A 1 406 ? 56.22600  14.45200  16.66300  1.000 281.30000 ? 406 MET A CG    1 
ATOM   3023 S  SD    . MET A 1 406 ? 55.25500  13.04500  16.16800  1.000 310.06000 ? 406 MET A SD    1 
ATOM   3024 C  CE    . MET A 1 406 ? 53.74700  13.40400  17.07800  1.000 292.07000 ? 406 MET A CE    1 
ATOM   3025 N  N     . ARG A 1 407 ? 54.67200  16.79800  19.30500  1.000 266.44000 ? 407 ARG A N     1 
ATOM   3026 C  CA    . ARG A 1 407 ? 54.59900  16.82300  20.75400  1.000 264.11000 ? 407 ARG A CA    1 
ATOM   3027 C  C     . ARG A 1 407 ? 54.76600  15.41600  21.31900  1.000 266.12000 ? 407 ARG A C     1 
ATOM   3028 O  O     . ARG A 1 407 ? 54.23900  14.44800  20.76200  1.000 267.01000 ? 407 ARG A O     1 
ATOM   3029 C  CB    . ARG A 1 407 ? 53.27100  17.44000  21.17000  1.000 265.67000 ? 407 ARG A CB    1 
ATOM   3030 C  CG    . ARG A 1 407 ? 52.72600  16.94800  22.47700  1.000 264.42000 ? 407 ARG A CG    1 
ATOM   3031 C  CD    . ARG A 1 407 ? 51.21800  16.95900  22.42800  1.000 265.78000 ? 407 ARG A CD    1 
ATOM   3032 N  NE    . ARG A 1 407 ? 50.65500  16.21800  23.54900  1.000 267.23000 ? 407 ARG A NE    1 
ATOM   3033 C  CZ    . ARG A 1 407 ? 50.49300  16.72700  24.76300  1.000 261.50000 ? 407 ARG A CZ    1 
ATOM   3034 N  NH1   . ARG A 1 407 ? 50.84100  17.98000  25.00800  1.000 261.00000 ? 407 ARG A NH1   1 
ATOM   3035 N  NH2   . ARG A 1 407 ? 49.97800  15.98900  25.73100  1.000 263.16000 ? 407 ARG A NH2   1 
ATOM   3036 N  N     . GLY A 1 408 ? 55.51300  15.30400  22.41500  1.000 265.60000 ? 408 GLY A N     1 
ATOM   3037 C  CA    . GLY A 1 408 ? 55.91700  14.02900  22.97800  1.000 268.67000 ? 408 GLY A CA    1 
ATOM   3038 C  C     . GLY A 1 408 ? 57.39700  13.76900  22.85300  1.000 266.49000 ? 408 GLY A C     1 
ATOM   3039 O  O     . GLY A 1 408 ? 57.95100  12.93500  23.58900  1.000 269.02000 ? 408 GLY A O     1 
ATOM   3040 N  N     . ASN A 1 409 ? 58.04700  14.44000  21.91600  1.000 259.73000 ? 409 ASN A N     1 
ATOM   3041 C  CA    . ASN A 1 409 ? 59.49200  14.52500  21.94400  1.000 260.06000 ? 409 ASN A CA    1 
ATOM   3042 C  C     . ASN A 1 409 ? 59.94300  15.08300  23.27100  1.000 261.40000 ? 409 ASN A C     1 
ATOM   3043 O  O     . ASN A 1 409 ? 59.35500  16.02300  23.80700  1.000 263.52000 ? 409 ASN A O     1 
ATOM   3044 C  CB    . ASN A 1 409 ? 59.99600  15.42500  20.83700  1.000 264.22000 ? 409 ASN A CB    1 
ATOM   3045 C  CG    . ASN A 1 409 ? 60.19300  14.69100  19.56300  1.000 270.92000 ? 409 ASN A CG    1 
ATOM   3046 O  OD1   . ASN A 1 409 ? 61.13500  13.91600  19.44500  1.000 282.11000 ? 409 ASN A OD1   1 
ATOM   3047 N  ND2   . ASN A 1 409 ? 59.30400  14.90600  18.59400  1.000 271.96000 ? 409 ASN A ND2   1 
ATOM   3048 N  N     . ALA A 1 410 ? 61.01400  14.52400  23.79200  1.000 268.56000 ? 410 ALA A N     1 
ATOM   3049 C  CA    . ALA A 1 410 ? 61.53100  15.09400  25.01300  1.000 263.27000 ? 410 ALA A CA    1 
ATOM   3050 C  C     . ALA A 1 410 ? 63.04100  14.98300  25.01300  1.000 269.56000 ? 410 ALA A C     1 
ATOM   3051 O  O     . ALA A 1 410 ? 63.62000  14.13600  24.32700  1.000 275.80000 ? 410 ALA A O     1 
ATOM   3052 C  CB    . ALA A 1 410 ? 60.92100  14.42000  26.24200  1.000 265.94000 ? 410 ALA A CB    1 
ATOM   3053 N  N     . TYR A 1 411 ? 63.66800  15.87500  25.77300  1.000 276.49000 ? 411 TYR A N     1 
ATOM   3054 C  CA    . TYR A 1 411 ? 65.10800  15.88000  25.98300  1.000 276.58000 ? 411 TYR A CA    1 
ATOM   3055 C  C     . TYR A 1 411 ? 65.38800  15.72200  27.46000  1.000 280.43000 ? 411 TYR A C     1 
ATOM   3056 O  O     . TYR A 1 411 ? 64.96800  16.55300  28.27100  1.000 285.71000 ? 411 TYR A O     1 
ATOM   3057 C  CB    . TYR A 1 411 ? 65.76300  17.16100  25.51500  1.000 277.16000 ? 411 TYR A CB    1 
ATOM   3058 C  CG    . TYR A 1 411 ? 67.17600  17.33100  26.04900  1.000 283.96000 ? 411 TYR A CG    1 
ATOM   3059 C  CD1   . TYR A 1 411 ? 68.09500  16.28900  25.98900  1.000 286.25000 ? 411 TYR A CD1   1 
ATOM   3060 C  CD2   . TYR A 1 411 ? 67.59300  18.54100  26.58200  1.000 283.67000 ? 411 TYR A CD2   1 
ATOM   3061 C  CE1   . TYR A 1 411 ? 69.36600  16.44300  26.45700  1.000 285.29000 ? 411 TYR A CE1   1 
ATOM   3062 C  CE2   . TYR A 1 411 ? 68.86800  18.71400  27.03500  1.000 288.38000 ? 411 TYR A CE2   1 
ATOM   3063 C  CZ    . TYR A 1 411 ? 69.75300  17.66600  26.97800  1.000 289.91000 ? 411 TYR A CZ    1 
ATOM   3064 O  OH    . TYR A 1 411 ? 71.03000  17.87100  27.45600  1.000 305.96000 ? 411 TYR A OH    1 
ATOM   3065 N  N     . ILE A 1 412 ? 66.12200  14.67600  27.79200  1.000 288.99000 ? 412 ILE A N     1 
ATOM   3066 C  CA    . ILE A 1 412 ? 66.45600  14.34400  29.16500  1.000 295.24000 ? 412 ILE A CA    1 
ATOM   3067 C  C     . ILE A 1 412 ? 67.87700  14.84200  29.44600  1.000 300.13000 ? 412 ILE A C     1 
ATOM   3068 O  O     . ILE A 1 412 ? 68.86400  14.24800  28.99300  1.000 296.27000 ? 412 ILE A O     1 
ATOM   3069 C  CB    . ILE A 1 412 ? 66.28800  12.84100  29.43800  1.000 296.70000 ? 412 ILE A CB    1 
ATOM   3070 C  CG1   . ILE A 1 412 ? 64.89500  12.38600  29.01800  1.000 296.01000 ? 412 ILE A CG1   1 
ATOM   3071 C  CG2   . ILE A 1 412 ? 66.34600  12.58000  30.89800  1.000 302.17000 ? 412 ILE A CG2   1 
ATOM   3072 C  CD1   . ILE A 1 412 ? 64.26600  11.19200  29.80200  1.000 284.64000 ? 412 ILE A CD1   1 
ATOM   3073 N  N     . VAL A 1 413 ? 67.95500  15.97100  30.16700  1.000 302.81000 ? 413 VAL A N     1 
ATOM   3074 C  CA    . VAL A 1 413 ? 69.20700  16.55900  30.63900  1.000 308.77000 ? 413 VAL A CA    1 
ATOM   3075 C  C     . VAL A 1 413 ? 69.89700  15.63100  31.64000  1.000 312.12000 ? 413 VAL A C     1 
ATOM   3076 O  O     . VAL A 1 413 ? 71.05300  15.23100  31.45300  1.000 311.76000 ? 413 VAL A O     1 
ATOM   3077 C  CB    . VAL A 1 413 ? 68.89300  17.94100  31.24600  1.000 306.61000 ? 413 VAL A CB    1 
ATOM   3078 C  CG1   . VAL A 1 413 ? 70.15400  18.73300  31.46300  1.000 302.56000 ? 413 VAL A CG1   1 
ATOM   3079 C  CG2   . VAL A 1 413 ? 67.91300  18.68800  30.34700  1.000 302.97000 ? 413 VAL A CG2   1 
ATOM   3080 N  N     . ASP A 1 414 ? 69.22700  15.32900  32.74800  1.000 304.62000 ? 414 ASP A N     1 
ATOM   3081 C  CA    . ASP A 1 414 ? 69.80900  14.47400  33.76800  1.000 293.34000 ? 414 ASP A CA    1 
ATOM   3082 C  C     . ASP A 1 414 ? 68.81000  13.39800  34.10700  1.000 292.37000 ? 414 ASP A C     1 
ATOM   3083 O  O     . ASP A 1 414 ? 67.68000  13.41200  33.61900  1.000 294.41000 ? 414 ASP A O     1 
ATOM   3084 C  CB    . ASP A 1 414 ? 70.17500  15.26100  35.01900  1.000 295.95000 ? 414 ASP A CB    1 
ATOM   3085 C  CG    . ASP A 1 414 ? 70.87300  16.55300  34.70200  1.000 308.29000 ? 414 ASP A CG    1 
ATOM   3086 O  OD1   . ASP A 1 414 ? 70.67600  17.53300  35.44600  1.000 314.61000 ? 414 ASP A OD1   1 
ATOM   3087 O  OD2   . ASP A 1 414 ? 71.60200  16.60700  33.69200  1.000 313.55000 ? 414 ASP A OD2   1 
ATOM   3088 N  N     . GLU A 1 415 ? 69.22200  12.47500  34.97100  1.000 278.47000 ? 415 GLU A N     1 
ATOM   3089 C  CA    . GLU A 1 415 ? 68.23300  11.56100  35.50500  1.000 279.30000 ? 415 GLU A CA    1 
ATOM   3090 C  C     . GLU A 1 415 ? 67.15400  12.30200  36.27300  1.000 273.66000 ? 415 GLU A C     1 
ATOM   3091 O  O     . GLU A 1 415 ? 66.10700  11.73400  36.59500  1.000 277.15000 ? 415 GLU A O     1 
ATOM   3092 C  CB    . GLU A 1 415 ? 68.92400  10.56100  36.39200  1.000 288.48000 ? 415 GLU A CB    1 
ATOM   3093 C  CG    . GLU A 1 415 ? 69.89100  9.78800   35.62000  1.000 296.72000 ? 415 GLU A CG    1 
ATOM   3094 C  CD    . GLU A 1 415 ? 70.11500  8.44500   36.22300  1.000 307.92000 ? 415 GLU A CD    1 
ATOM   3095 O  OE1   . GLU A 1 415 ? 71.27900  8.17200   36.58800  1.000 319.84000 ? 415 GLU A OE1   1 
ATOM   3096 O  OE2   . GLU A 1 415 ? 69.13400  7.66900   36.32600  1.000 311.24000 ? 415 GLU A OE2   1 
ATOM   3097 N  N     . LYS A 1 416 ? 67.39100  13.57000  36.59200  1.000 276.41000 ? 416 LYS A N     1 
ATOM   3098 C  CA    . LYS A 1 416 ? 66.44200  14.31400  37.42500  1.000 279.98000 ? 416 LYS A CA    1 
ATOM   3099 C  C     . LYS A 1 416 ? 65.63500  15.33800  36.61200  1.000 274.81000 ? 416 LYS A C     1 
ATOM   3100 O  O     . LYS A 1 416 ? 64.40700  15.37800  36.72400  1.000 279.27000 ? 416 LYS A O     1 
ATOM   3101 C  CB    . LYS A 1 416 ? 67.18800  14.98800  38.59500  1.000 294.48000 ? 416 LYS A CB    1 
ATOM   3102 C  CG    . LYS A 1 416 ? 66.63800  14.64700  40.06200  1.000 298.28000 ? 416 LYS A CG    1 
ATOM   3103 C  CD    . LYS A 1 416 ? 66.81000  13.12800  40.52600  1.000 290.58000 ? 416 LYS A CD    1 
ATOM   3104 C  CE    . LYS A 1 416 ? 66.62700  12.81800  42.05500  1.000 274.63000 ? 416 LYS A CE    1 
ATOM   3105 N  NZ    . LYS A 1 416 ? 66.75300  11.35100  42.31000  1.000 275.85000 ? 416 LYS A NZ    1 
ATOM   3106 N  N     . LYS A 1 417 ? 66.29000  16.11700  35.74700  1.000 281.16000 ? 417 LYS A N     1 
ATOM   3107 C  CA    . LYS A 1 417 ? 65.68800  17.22700  35.01000  1.000 280.01000 ? 417 LYS A CA    1 
ATOM   3108 C  C     . LYS A 1 417 ? 65.55900  16.87600  33.53700  1.000 282.91000 ? 417 LYS A C     1 
ATOM   3109 O  O     . LYS A 1 417 ? 66.47300  16.28100  32.97200  1.000 289.65000 ? 417 LYS A O     1 
ATOM   3110 C  CB    . LYS A 1 417 ? 66.55600  18.47500  35.19300  1.000 281.68000 ? 417 LYS A CB    1 
ATOM   3111 C  CG    . LYS A 1 417 ? 67.74400  18.16600  36.07600  1.000 286.22000 ? 417 LYS A CG    1 
ATOM   3112 C  CD    . LYS A 1 417 ? 68.41300  19.39800  36.66300  1.000 286.77000 ? 417 LYS A CD    1 
ATOM   3113 C  CE    . LYS A 1 417 ? 69.19300  18.97100  37.90500  1.000 284.37000 ? 417 LYS A CE    1 
ATOM   3114 N  NZ    . LYS A 1 417 ? 69.76500  20.13100  38.63400  1.000 289.24000 ? 417 LYS A NZ    1 
ATOM   3115 N  N     . ALA A 1 418 ? 64.42500  17.22000  32.91700  1.000 284.21000 ? 418 ALA A N     1 
ATOM   3116 C  CA    . ALA A 1 418 ? 64.21100  16.90300  31.49700  1.000 286.09000 ? 418 ALA A CA    1 
ATOM   3117 C  C     . ALA A 1 418 ? 63.45900  18.02800  30.80500  1.000 283.20000 ? 418 ALA A C     1 
ATOM   3118 O  O     . ALA A 1 418 ? 62.89100  18.91000  31.45100  1.000 280.98000 ? 418 ALA A O     1 
ATOM   3119 C  CB    . ALA A 1 418 ? 63.43500  15.59100  31.25100  1.000 285.40000 ? 418 ALA A CB    1 
ATOM   3120 N  N     . PHE A 1 419 ? 63.46200  17.97100  29.46900  1.000 282.86000 ? 419 PHE A N     1 
ATOM   3121 C  CA    . PHE A 1 419 ? 62.68400  18.85900  28.61300  1.000 284.42000 ? 419 PHE A CA    1 
ATOM   3122 C  C     . PHE A 1 419 ? 61.52500  18.13000  27.96600  1.000 283.76000 ? 419 PHE A C     1 
ATOM   3123 O  O     . PHE A 1 419 ? 61.72600  17.13200  27.27800  1.000 279.45000 ? 419 PHE A O     1 
ATOM   3124 C  CB    . PHE A 1 419 ? 63.52800  19.45400  27.51200  1.000 280.74000 ? 419 PHE A CB    1 
ATOM   3125 C  CG    . PHE A 1 419 ? 64.28200  20.60900  27.95100  1.000 278.87000 ? 419 PHE A CG    1 
ATOM   3126 C  CD1   . PHE A 1 419 ? 63.67700  21.84900  28.02500  1.000 285.34000 ? 419 PHE A CD1   1 
ATOM   3127 C  CD2   . PHE A 1 419 ? 65.58100  20.46100  28.36600  1.000 278.52000 ? 419 PHE A CD2   1 
ATOM   3128 C  CE1   . PHE A 1 419 ? 64.37200  22.92600  28.46600  1.000 286.42000 ? 419 PHE A CE1   1 
ATOM   3129 C  CE2   . PHE A 1 419 ? 66.27000  21.52800  28.80100  1.000 290.20000 ? 419 PHE A CE2   1 
ATOM   3130 C  CZ    . PHE A 1 419 ? 65.68300  22.78000  28.86300  1.000 292.32000 ? 419 PHE A CZ    1 
ATOM   3131 N  N     . LEU A 1 420 ? 60.32600  18.65900  28.14900  1.000 285.51000 ? 420 LEU A N     1 
ATOM   3132 C  CA    . LEU A 1 420 ? 59.11400  18.02400  27.66600  1.000 275.36000 ? 420 LEU A CA    1 
ATOM   3133 C  C     . LEU A 1 420 ? 58.42400  18.93200  26.66300  1.000 274.59000 ? 420 LEU A C     1 
ATOM   3134 O  O     . LEU A 1 420 ? 58.23100  20.12000  26.91100  1.000 274.60000 ? 420 LEU A O     1 
ATOM   3135 C  CB    . LEU A 1 420 ? 58.16000  17.71200  28.80000  1.000 274.40000 ? 420 LEU A CB    1 
ATOM   3136 C  CG    . LEU A 1 420 ? 56.95400  16.90800  28.32300  1.000 275.04000 ? 420 LEU A CG    1 
ATOM   3137 C  CD1   . LEU A 1 420 ? 57.44000  15.83800  27.35800  1.000 273.69000 ? 420 LEU A CD1   1 
ATOM   3138 C  CD2   . LEU A 1 420 ? 56.19500  16.28800  29.50900  1.000 273.76000 ? 420 LEU A CD2   1 
ATOM   3139 N  N     . TRP A 1 421 ? 58.00600  18.36800  25.55200  1.000 271.61000 ? 421 TRP A N     1 
ATOM   3140 C  CA    . TRP A 1 421 ? 57.23600  19.11200  24.56500  1.000 267.87000 ? 421 TRP A CA    1 
ATOM   3141 C  C     . TRP A 1 421 ? 55.78900  18.66200  24.64600  1.000 267.29000 ? 421 TRP A C     1 
ATOM   3142 O  O     . TRP A 1 421 ? 55.38400  17.69000  24.00300  1.000 267.11000 ? 421 TRP A O     1 
ATOM   3143 C  CB    . TRP A 1 421 ? 57.81100  18.93700  23.17400  1.000 273.21000 ? 421 TRP A CB    1 
ATOM   3144 C  CG    . TRP A 1 421 ? 58.83800  19.98400  22.93000  1.000 278.21000 ? 421 TRP A CG    1 
ATOM   3145 C  CD1   . TRP A 1 421 ? 58.64000  21.28300  22.56200  1.000 280.57000 ? 421 TRP A CD1   1 
ATOM   3146 C  CD2   . TRP A 1 421 ? 60.24400  19.80900  23.06600  1.000 275.65000 ? 421 TRP A CD2   1 
ATOM   3147 N  NE1   . TRP A 1 421 ? 59.85900  21.92400  22.43200  1.000 277.79000 ? 421 TRP A NE1   1 
ATOM   3148 C  CE2   . TRP A 1 421 ? 60.85500  21.03100  22.72000  1.000 274.75000 ? 421 TRP A CE2   1 
ATOM   3149 C  CE3   . TRP A 1 421 ? 61.04900  18.72000  23.42500  1.000 275.60000 ? 421 TRP A CE3   1 
ATOM   3150 C  CZ2   . TRP A 1 421 ? 62.22500  21.20900  22.73800  1.000 274.40000 ? 421 TRP A CZ2   1 
ATOM   3151 C  CZ3   . TRP A 1 421 ? 62.41000  18.89000  23.45200  1.000 279.37000 ? 421 TRP A CZ3   1 
ATOM   3152 C  CH2   . TRP A 1 421 ? 62.98800  20.13900  23.11900  1.000 282.23000 ? 421 TRP A CH2   1 
ATOM   3153 N  N     . THR A 1 422 ? 55.02400  19.36500  25.46300  1.000 265.43000 ? 422 THR A N     1 
ATOM   3154 C  CA    . THR A 1 422 ? 53.58100  19.29200  25.43700  1.000 264.03000 ? 422 THR A CA    1 
ATOM   3155 C  C     . THR A 1 422 ? 52.98400  20.07800  24.29100  1.000 265.63000 ? 422 THR A C     1 
ATOM   3156 O  O     . THR A 1 422 ? 51.77800  19.97200  24.05000  1.000 269.95000 ? 422 THR A O     1 
ATOM   3157 C  CB    . THR A 1 422 ? 53.03200  19.83200  26.73000  1.000 270.66000 ? 422 THR A CB    1 
ATOM   3158 O  OG1   . THR A 1 422 ? 53.57700  21.14200  26.92300  1.000 274.28000 ? 422 THR A OG1   1 
ATOM   3159 C  CG2   . THR A 1 422 ? 53.45900  18.96100  27.88200  1.000 282.88000 ? 422 THR A CG2   1 
ATOM   3160 N  N     . LEU A 1 423 ? 53.78900  20.89900  23.62400  1.000 265.30000 ? 423 LEU A N     1 
ATOM   3161 C  CA    . LEU A 1 423 ? 53.36000  21.69800  22.48600  1.000 267.26000 ? 423 LEU A CA    1 
ATOM   3162 C  C     . LEU A 1 423 ? 54.08800  21.22000  21.24500  1.000 267.44000 ? 423 LEU A C     1 
ATOM   3163 O  O     . LEU A 1 423 ? 55.02200  20.42200  21.31500  1.000 269.08000 ? 423 LEU A O     1 
ATOM   3164 C  CB    . LEU A 1 423 ? 53.63400  23.19100  22.71100  1.000 270.15000 ? 423 LEU A CB    1 
ATOM   3165 C  CG    . LEU A 1 423 ? 52.53400  24.00500  23.38900  1.000 285.54000 ? 423 LEU A CG    1 
ATOM   3166 C  CD1   . LEU A 1 423 ? 51.35100  23.12000  23.78500  1.000 290.04000 ? 423 LEU A CD1   1 
ATOM   3167 C  CD2   . LEU A 1 423 ? 53.04000  24.79100  24.59900  1.000 288.17000 ? 423 LEU A CD2   1 
ATOM   3168 N  N     . GLY A 1 424 ? 53.66100  21.72000  20.09000  1.000 267.04000 ? 424 GLY A N     1 
ATOM   3169 C  CA    . GLY A 1 424 ? 54.25400  21.35200  18.83700  1.000 267.81000 ? 424 GLY A CA    1 
ATOM   3170 C  C     . GLY A 1 424 ? 53.36800  20.40600  18.02700  1.000 267.06000 ? 424 GLY A C     1 
ATOM   3171 O  O     . GLY A 1 424 ? 52.29000  19.99400  18.46700  1.000 270.01000 ? 424 GLY A O     1 
ATOM   3172 N  N     . PHE A 1 425 ? 53.85400  20.06800  16.84600  1.000 272.18000 ? 425 PHE A N     1 
ATOM   3173 C  CA    . PHE A 1 425 ? 52.99100  19.47300  15.83200  1.000 272.48000 ? 425 PHE A CA    1 
ATOM   3174 C  C     . PHE A 1 425 ? 52.29600  18.22000  16.32300  1.000 271.39000 ? 425 PHE A C     1 
ATOM   3175 O  O     . PHE A 1 425 ? 52.90700  17.34500  16.93400  1.000 271.62000 ? 425 PHE A O     1 
ATOM   3176 C  CB    . PHE A 1 425 ? 53.74600  19.09500  14.57500  1.000 274.43000 ? 425 PHE A CB    1 
ATOM   3177 C  CG    . PHE A 1 425 ? 52.83800  18.47900  13.56600  1.000 273.07000 ? 425 PHE A CG    1 
ATOM   3178 C  CD1   . PHE A 1 425 ? 52.57800  17.11500  13.56200  1.000 274.47000 ? 425 PHE A CD1   1 
ATOM   3179 C  CD2   . PHE A 1 425 ? 52.15000  19.28800  12.69400  1.000 277.39000 ? 425 PHE A CD2   1 
ATOM   3180 C  CE1   . PHE A 1 425 ? 51.70600  16.59100  12.67900  1.000 273.41000 ? 425 PHE A CE1   1 
ATOM   3181 C  CE2   . PHE A 1 425 ? 51.28700  18.76300  11.80500  1.000 279.18000 ? 425 PHE A CE2   1 
ATOM   3182 C  CZ    . PHE A 1 425 ? 51.05800  17.40800  11.79000  1.000 277.04000 ? 425 PHE A CZ    1 
ATOM   3183 N  N     . VAL A 1 426 ? 51.02500  18.09800  15.98100  1.000 268.75000 ? 426 VAL A N     1 
ATOM   3184 C  CA    . VAL A 1 426 ? 50.35500  16.86100  16.32800  1.000 270.12000 ? 426 VAL A CA    1 
ATOM   3185 C  C     . VAL A 1 426 ? 49.74000  16.26000  15.07900  1.000 267.28000 ? 426 VAL A C     1 
ATOM   3186 O  O     . VAL A 1 426 ? 49.07200  16.96100  14.30000  1.000 269.74000 ? 426 VAL A O     1 
ATOM   3187 C  CB    . VAL A 1 426 ? 49.34500  17.10800  17.45500  1.000 284.36000 ? 426 VAL A CB    1 
ATOM   3188 C  CG1   . VAL A 1 426 ? 48.41800  15.91200  17.65400  1.000 282.95000 ? 426 VAL A CG1   1 
ATOM   3189 C  CG2   . VAL A 1 426 ? 50.11100  17.38400  18.72900  1.000 283.47000 ? 426 VAL A CG2   1 
ATOM   3190 N  N     . PRO A 1 427 ? 49.99300  14.97500  14.84600  1.000 267.23000 ? 427 PRO A N     1 
ATOM   3191 C  CA    . PRO A 1 427 ? 49.53800  14.35700  13.60700  1.000 276.63000 ? 427 PRO A CA    1 
ATOM   3192 C  C     . PRO A 1 427 ? 48.04300  14.14500  13.55300  1.000 280.75000 ? 427 PRO A C     1 
ATOM   3193 O  O     . PRO A 1 427 ? 47.44200  14.49300  12.53300  1.000 289.34000 ? 427 PRO A O     1 
ATOM   3194 C  CB    . PRO A 1 427 ? 50.32300  13.04300  13.57600  1.000 283.67000 ? 427 PRO A CB    1 
ATOM   3195 C  CG    . PRO A 1 427 ? 50.52900  12.72100  14.99500  1.000 282.28000 ? 427 PRO A CG    1 
ATOM   3196 C  CD    . PRO A 1 427 ? 50.68900  14.01900  15.71600  1.000 270.28000 ? 427 PRO A CD    1 
ATOM   3197 N  N     . LYS A 1 428 ? 47.39700  13.62400  14.60100  1.000 268.24000 ? 428 LYS A N     1 
ATOM   3198 C  CA    . LYS A 1 428 ? 45.95100  13.42600  14.48400  1.000 262.11000 ? 428 LYS A CA    1 
ATOM   3199 C  C     . LYS A 1 428 ? 45.22500  14.75700  14.23000  1.000 261.43000 ? 428 LYS A C     1 
ATOM   3200 O  O     . LYS A 1 428 ? 44.07300  14.77300  13.77100  1.000 262.32000 ? 428 LYS A O     1 
ATOM   3201 C  CB    . LYS A 1 428 ? 45.40600  12.71100  15.72300  1.000 259.09000 ? 428 LYS A CB    1 
ATOM   3202 C  CG    . LYS A 1 428 ? 43.86200  12.66900  15.79400  1.000 260.32000 ? 428 LYS A CG    1 
ATOM   3203 C  CD    . LYS A 1 428 ? 43.28400  13.87900  16.54000  1.000 261.70000 ? 428 LYS A CD    1 
ATOM   3204 C  CE    . LYS A 1 428 ? 41.83900  14.13400  16.20800  1.000 259.65000 ? 428 LYS A CE    1 
ATOM   3205 N  NZ    . LYS A 1 428 ? 41.69900  14.76200  14.89700  1.000 262.97000 ? 428 LYS A NZ    1 
ATOM   3206 N  N     . LEU A 1 429 ? 45.89800  15.88500  14.49500  1.000 273.36000 ? 429 LEU A N     1 
ATOM   3207 C  CA    . LEU A 1 429 ? 45.36200  17.20500  14.18900  1.000 274.65000 ? 429 LEU A CA    1 
ATOM   3208 C  C     . LEU A 1 429 ? 45.96100  17.79900  12.94300  1.000 274.93000 ? 429 LEU A C     1 
ATOM   3209 O  O     . LEU A 1 429 ? 45.38200  18.73200  12.38400  1.000 277.33000 ? 429 LEU A O     1 
ATOM   3210 C  CB    . LEU A 1 429 ? 45.62300  18.17700  15.33400  1.000 273.34000 ? 429 LEU A CB    1 
ATOM   3211 C  CG    . LEU A 1 429 ? 44.84400  17.88200  16.61900  1.000 283.10000 ? 429 LEU A CG    1 
ATOM   3212 C  CD1   . LEU A 1 429 ? 45.34200  18.75500  17.78500  1.000 285.68000 ? 429 LEU A CD1   1 
ATOM   3213 C  CD2   . LEU A 1 429 ? 43.35300  18.06600  16.34600  1.000 282.14000 ? 429 LEU A CD2   1 
ATOM   3214 N  N     . GLN A 1 430 ? 47.10800  17.30300  12.51400  1.000 275.24000 ? 430 GLN A N     1 
ATOM   3215 C  CA    . GLN A 1 430 ? 47.82500  17.92500  11.42600  1.000 276.84000 ? 430 GLN A CA    1 
ATOM   3216 C  C     . GLN A 1 430 ? 47.88000  19.41600  11.66400  1.000 270.35000 ? 430 GLN A C     1 
ATOM   3217 O  O     . GLN A 1 430 ? 47.56800  20.23600  10.79500  1.000 272.58000 ? 430 GLN A O     1 
ATOM   3218 C  CB    . GLN A 1 430 ? 47.20700  17.58900  10.06900  1.000 281.95000 ? 430 GLN A CB    1 
ATOM   3219 C  CG    . GLN A 1 430 ? 47.54800  16.15000  9.63300   1.000 291.79000 ? 430 GLN A CG    1 
ATOM   3220 C  CD    . GLN A 1 430 ? 48.97700  15.98400  9.09700   1.000 287.06000 ? 430 GLN A CD    1 
ATOM   3221 O  OE1   . GLN A 1 430 ? 49.47000  16.84800  8.38300   1.000 282.70000 ? 430 GLN A OE1   1 
ATOM   3222 N  NE2   . GLN A 1 430 ? 49.61900  14.85900  9.41000   1.000 290.88000 ? 430 GLN A NE2   1 
ATOM   3223 N  N     . SER A 1 431 ? 48.21500  19.75100  12.90600  1.000 267.11000 ? 431 SER A N     1 
ATOM   3224 C  CA    . SER A 1 431 ? 48.41000  21.13100  13.30300  1.000 266.23000 ? 431 SER A CA    1 
ATOM   3225 C  C     . SER A 1 431 ? 49.40900  21.15800  14.44100  1.000 265.50000 ? 431 SER A C     1 
ATOM   3226 O  O     . SER A 1 431 ? 49.58000  20.17300  15.16600  1.000 269.74000 ? 431 SER A O     1 
ATOM   3227 C  CB    . SER A 1 431 ? 47.10100  21.80900  13.71700  1.000 271.71000 ? 431 SER A CB    1 
ATOM   3228 O  OG    . SER A 1 431 ? 47.33700  23.16000  14.07700  1.000 279.72000 ? 431 SER A OG    1 
ATOM   3229 N  N     . THR A 1 432 ? 50.09500  22.29200  14.55500  1.000 275.34000 ? 432 THR A N     1 
ATOM   3230 C  CA    . THR A 1 432 ? 50.90400  22.56500  15.73000  1.000 275.26000 ? 432 THR A CA    1 
ATOM   3231 C  C     . THR A 1 432 ? 50.03100  23.10600  16.83700  1.000 275.80000 ? 432 THR A C     1 
ATOM   3232 O  O     . THR A 1 432 ? 49.19000  23.98200  16.61900  1.000 277.20000 ? 432 THR A O     1 
ATOM   3233 C  CB    . THR A 1 432 ? 51.99100  23.60200  15.48100  1.000 276.49000 ? 432 THR A CB    1 
ATOM   3234 O  OG1   . THR A 1 432 ? 52.50700  23.99500  16.76000  1.000 277.23000 ? 432 THR A OG1   1 
ATOM   3235 C  CG2   . THR A 1 432 ? 51.41600  24.85000  14.79500  1.000 274.07000 ? 432 THR A CG2   1 
ATOM   3236 N  N     . LEU A 1 433 ? 50.24400  22.58400  18.03900  1.000 273.60000 ? 433 LEU A N     1 
ATOM   3237 C  CA    . LEU A 1 433 ? 49.44100  23.05700  19.15500  1.000 281.66000 ? 433 LEU A CA    1 
ATOM   3238 C  C     . LEU A 1 433 ? 49.82200  24.48400  19.51400  1.000 279.66000 ? 433 LEU A C     1 
ATOM   3239 O  O     . LEU A 1 433 ? 48.98400  25.39400  19.45900  1.000 281.85000 ? 433 LEU A O     1 
ATOM   3240 C  CB    . LEU A 1 433 ? 49.59400  22.10900  20.34600  1.000 292.45000 ? 433 LEU A CB    1 
ATOM   3241 C  CG    . LEU A 1 433 ? 48.87500  20.75600  20.13800  1.000 296.82000 ? 433 LEU A CG    1 
ATOM   3242 C  CD1   . LEU A 1 433 ? 49.14700  19.81700  21.31200  1.000 297.24000 ? 433 LEU A CD1   1 
ATOM   3243 C  CD2   . LEU A 1 433 ? 47.35000  20.93300  19.94500  1.000 282.76000 ? 433 LEU A CD2   1 
ATOM   3244 N  N     . SER A 1 434 ? 51.09000  24.69500  19.85100  1.000 276.81000 ? 434 SER A N     1 
ATOM   3245 C  CA    . SER A 1 434 ? 51.65400  26.03400  19.82400  1.000 284.44000 ? 434 SER A CA    1 
ATOM   3246 C  C     . SER A 1 434 ? 51.70900  26.51200  18.37500  1.000 287.85000 ? 434 SER A C     1 
ATOM   3247 O  O     . SER A 1 434 ? 52.34700  25.88100  17.53100  1.000 286.37000 ? 434 SER A O     1 
ATOM   3248 C  CB    . SER A 1 434 ? 53.04700  26.05000  20.46300  1.000 285.46000 ? 434 SER A CB    1 
ATOM   3249 O  OG    . SER A 1 434 ? 53.39300  27.36400  20.92200  1.000 292.40000 ? 434 SER A OG    1 
ATOM   3250 N  N     . MET A 1 435 ? 51.02400  27.62300  18.08200  1.000 282.27000 ? 435 MET A N     1 
ATOM   3251 C  CA    . MET A 1 435 ? 50.90600  28.10400  16.70800  1.000 278.72000 ? 435 MET A CA    1 
ATOM   3252 C  C     . MET A 1 435 ? 52.20400  28.67400  16.14500  1.000 286.44000 ? 435 MET A C     1 
ATOM   3253 O  O     . MET A 1 435 ? 52.33100  28.77900  14.92400  1.000 302.26000 ? 435 MET A O     1 
ATOM   3254 C  CB    . MET A 1 435 ? 49.79700  29.15100  16.60600  1.000 297.37000 ? 435 MET A CB    1 
ATOM   3255 C  CG    . MET A 1 435 ? 48.44100  28.57000  16.36700  1.000 299.31000 ? 435 MET A CG    1 
ATOM   3256 S  SD    . MET A 1 435 ? 47.95500  27.53400  17.74400  1.000 318.31000 ? 435 MET A SD    1 
ATOM   3257 C  CE    . MET A 1 435 ? 46.79500  28.64800  18.52700  1.000 289.98000 ? 435 MET A CE    1 
ATOM   3258 N  N     . GLU A 1 436 ? 53.16800  29.03500  16.98500  1.000 292.04000 ? 436 GLU A N     1 
ATOM   3259 C  CA    . GLU A 1 436 ? 54.51100  29.35100  16.52200  1.000 292.11000 ? 436 GLU A CA    1 
ATOM   3260 C  C     . GLU A 1 436 ? 55.42000  28.16700  16.84300  1.000 289.88000 ? 436 GLU A C     1 
ATOM   3261 O  O     . GLU A 1 436 ? 54.95800  27.03300  17.02300  1.000 290.00000 ? 436 GLU A O     1 
ATOM   3262 C  CB    . GLU A 1 436 ? 55.01300  30.65500  17.15200  1.000 297.20000 ? 436 GLU A CB    1 
ATOM   3263 C  CG    . GLU A 1 436 ? 55.96600  31.49800  16.30100  1.000 292.34000 ? 436 GLU A CG    1 
ATOM   3264 C  CD    . GLU A 1 436 ? 56.10600  32.91000  16.85200  1.000 307.84000 ? 436 GLU A CD    1 
ATOM   3265 O  OE1   . GLU A 1 436 ? 56.39900  33.03500  18.05100  1.000 318.10000 ? 436 GLU A OE1   1 
ATOM   3266 O  OE2   . GLU A 1 436 ? 55.93100  33.89200  16.10300  1.000 302.76000 ? 436 GLU A OE2   1 
ATOM   3267 N  N     . VAL A 1 437 ? 56.72200  28.43200  16.91900  1.000 282.43000 ? 437 VAL A N     1 
ATOM   3268 C  CA    . VAL A 1 437 ? 57.66500  27.33800  17.16900  1.000 275.27000 ? 437 VAL A CA    1 
ATOM   3269 C  C     . VAL A 1 437 ? 57.62800  26.96900  18.63500  1.000 279.76000 ? 437 VAL A C     1 
ATOM   3270 O  O     . VAL A 1 437 ? 57.93400  27.82400  19.48400  1.000 286.78000 ? 437 VAL A O     1 
ATOM   3271 C  CB    . VAL A 1 437 ? 59.07700  27.74100  16.78400  1.000 272.23000 ? 437 VAL A CB    1 
ATOM   3272 C  CG1   . VAL A 1 437 ? 59.89900  26.49100  16.59400  1.000 278.63000 ? 437 VAL A CG1   1 
ATOM   3273 C  CG2   . VAL A 1 437 ? 59.02900  28.56900  15.55100  1.000 279.30000 ? 437 VAL A CG2   1 
ATOM   3274 N  N     . PRO A 1 438 ? 57.34300  25.71800  18.98200  1.000 287.71000 ? 438 PRO A N     1 
ATOM   3275 C  CA    . PRO A 1 438 ? 56.93600  25.38900  20.35400  1.000 291.54000 ? 438 PRO A CA    1 
ATOM   3276 C  C     . PRO A 1 438 ? 58.05300  25.46500  21.38400  1.000 288.96000 ? 438 PRO A C     1 
ATOM   3277 O  O     . PRO A 1 438 ? 59.22500  25.19700  21.11400  1.000 284.41000 ? 438 PRO A O     1 
ATOM   3278 C  CB    . PRO A 1 438 ? 56.41200  23.95100  20.23600  1.000 287.76000 ? 438 PRO A CB    1 
ATOM   3279 C  CG    . PRO A 1 438 ? 56.98500  23.42800  18.96800  1.000 288.05000 ? 438 PRO A CG    1 
ATOM   3280 C  CD    . PRO A 1 438 ? 57.18900  24.58500  18.06200  1.000 284.43000 ? 438 PRO A CD    1 
ATOM   3281 N  N     . ASN A 1 439 ? 57.65900  25.85000  22.58900  1.000 288.57000 ? 439 ASN A N     1 
ATOM   3282 C  CA    . ASN A 1 439 ? 58.57600  25.92900  23.71700  1.000 289.91000 ? 439 ASN A CA    1 
ATOM   3283 C  C     . ASN A 1 439 ? 58.35100  24.72100  24.61500  1.000 281.06000 ? 439 ASN A C     1 
ATOM   3284 O  O     . ASN A 1 439 ? 57.22900  24.51600  25.09800  1.000 283.53000 ? 439 ASN A O     1 
ATOM   3285 C  CB    . ASN A 1 439 ? 58.38100  27.23600  24.49300  1.000 303.23000 ? 439 ASN A CB    1 
ATOM   3286 C  CG    . ASN A 1 439 ? 59.21000  28.39100  23.91300  1.000 312.62000 ? 439 ASN A CG    1 
ATOM   3287 O  OD1   . ASN A 1 439 ? 60.36700  28.58900  24.28900  1.000 312.82000 ? 439 ASN A OD1   1 
ATOM   3288 N  ND2   . ASN A 1 439 ? 58.61400  29.15600  23.00400  1.000 317.57000 ? 439 ASN A ND2   1 
ATOM   3289 N  N     . PRO A 1 440 ? 59.33300  23.84700  24.78600  1.000 275.60000 ? 440 PRO A N     1 
ATOM   3290 C  CA    . PRO A 1 440 ? 59.18900  22.76200  25.75400  1.000 277.49000 ? 440 PRO A CA    1 
ATOM   3291 C  C     . PRO A 1 440 ? 59.21500  23.27800  27.15900  1.000 286.82000 ? 440 PRO A C     1 
ATOM   3292 O  O     . PRO A 1 440 ? 59.57000  24.42600  27.41400  1.000 294.50000 ? 440 PRO A O     1 
ATOM   3293 C  CB    . PRO A 1 440 ? 60.42800  21.92300  25.54100  1.000 280.27000 ? 440 PRO A CB    1 
ATOM   3294 C  CG    . PRO A 1 440 ? 61.42700  22.90700  25.12900  1.000 282.74000 ? 440 PRO A CG    1 
ATOM   3295 C  CD    . PRO A 1 440 ? 60.68200  23.87000  24.21900  1.000 280.65000 ? 440 PRO A CD    1 
ATOM   3296 N  N     . ILE A 1 441 ? 58.90400  22.39000  28.09700  1.000 285.77000 ? 441 ILE A N     1 
ATOM   3297 C  CA    . ILE A 1 441 ? 58.81600  22.78600  29.50200  1.000 292.50000 ? 441 ILE A CA    1 
ATOM   3298 C  C     . ILE A 1 441 ? 59.87900  22.03900  30.31600  1.000 289.12000 ? 441 ILE A C     1 
ATOM   3299 O  O     . ILE A 1 441 ? 59.93100  20.79800  30.30900  1.000 287.97000 ? 441 ILE A O     1 
ATOM   3300 C  CB    . ILE A 1 441 ? 57.38700  22.60600  30.07700  1.000 294.27000 ? 441 ILE A CB    1 
ATOM   3301 C  CG1   . ILE A 1 441 ? 56.83400  21.17300  29.90500  1.000 288.64000 ? 441 ILE A CG1   1 
ATOM   3302 C  CG2   . ILE A 1 441 ? 56.41600  23.64500  29.49100  1.000 293.89000 ? 441 ILE A CG2   1 
ATOM   3303 C  CD1   . ILE A 1 441 ? 55.40200  21.06500  30.43100  1.000 290.11000 ? 441 ILE A CD1   1 
ATOM   3304 N  N     . PHE A 1 442 ? 60.75800  22.81900  30.96800  1.000 285.50000 ? 442 PHE A N     1 
ATOM   3305 C  CA    . PHE A 1 442 ? 61.74600  22.30500  31.90500  1.000 280.40000 ? 442 PHE A CA    1 
ATOM   3306 C  C     . PHE A 1 442 ? 61.02800  21.61500  33.04900  1.000 278.99000 ? 442 PHE A C     1 
ATOM   3307 O  O     . PHE A 1 442 ? 60.12200  22.17800  33.66800  1.000 279.21000 ? 442 PHE A O     1 
ATOM   3308 C  CB    . PHE A 1 442 ? 62.60100  23.45200  32.43700  1.000 282.24000 ? 442 PHE A CB    1 
ATOM   3309 C  CG    . PHE A 1 442 ? 64.01600  23.07000  32.82700  1.000 282.70000 ? 442 PHE A CG    1 
ATOM   3310 C  CD1   . PHE A 1 442 ? 65.02800  24.03000  32.84400  1.000 288.28000 ? 442 PHE A CD1   1 
ATOM   3311 C  CD2   . PHE A 1 442 ? 64.33700  21.77400  33.19300  1.000 284.42000 ? 442 PHE A CD2   1 
ATOM   3312 C  CE1   . PHE A 1 442 ? 66.33200  23.69900  33.19200  1.000 289.47000 ? 442 PHE A CE1   1 
ATOM   3313 C  CE2   . PHE A 1 442 ? 65.64000  21.43100  33.54100  1.000 285.04000 ? 442 PHE A CE2   1 
ATOM   3314 C  CZ    . PHE A 1 442 ? 66.64800  22.40300  33.54100  1.000 293.28000 ? 442 PHE A CZ    1 
ATOM   3315 N  N     . ILE A 1 443 ? 61.40000  20.36700  33.29000  1.000 281.83000 ? 443 ILE A N     1 
ATOM   3316 C  CA    . ILE A 1 443 ? 60.78200  19.53900  34.31300  1.000 287.30000 ? 443 ILE A CA    1 
ATOM   3317 C  C     . ILE A 1 443 ? 61.91500  19.01300  35.18000  1.000 290.39000 ? 443 ILE A C     1 
ATOM   3318 O  O     . ILE A 1 443 ? 62.74700  18.23100  34.70400  1.000 287.31000 ? 443 ILE A O     1 
ATOM   3319 C  CB    . ILE A 1 443 ? 59.96300  18.38300  33.70800  1.000 286.67000 ? 443 ILE A CB    1 
ATOM   3320 C  CG1   . ILE A 1 443 ? 58.75900  18.92000  32.94800  1.000 278.31000 ? 443 ILE A CG1   1 
ATOM   3321 C  CG2   . ILE A 1 443 ? 59.49300  17.44000  34.80300  1.000 293.09000 ? 443 ILE A CG2   1 
ATOM   3322 C  CD1   . ILE A 1 443 ? 57.85700  17.86100  32.33700  1.000 271.26000 ? 443 ILE A CD1   1 
ATOM   3323 N  N     . GLU A 1 444 ? 61.97400  19.47100  36.43000  1.000 281.36000 ? 444 GLU A N     1 
ATOM   3324 C  CA    . GLU A 1 444 ? 62.99800  19.05800  37.37700  1.000 276.58000 ? 444 GLU A CA    1 
ATOM   3325 C  C     . GLU A 1 444 ? 62.34900  18.44600  38.59400  1.000 273.49000 ? 444 GLU A C     1 
ATOM   3326 O  O     . GLU A 1 444 ? 61.57500  19.11600  39.27800  1.000 271.43000 ? 444 GLU A O     1 
ATOM   3327 C  CB    . GLU A 1 444 ? 63.83300  20.23000  37.83500  1.000 286.95000 ? 444 GLU A CB    1 
ATOM   3328 C  CG    . GLU A 1 444 ? 65.23000  19.78900  38.06000  1.000 289.16000 ? 444 GLU A CG    1 
ATOM   3329 C  CD    . GLU A 1 444 ? 65.91000  20.52900  39.15300  1.000 293.07000 ? 444 GLU A CD    1 
ATOM   3330 O  OE1   . GLU A 1 444 ? 66.91500  19.98900  39.64400  1.000 293.03000 ? 444 GLU A OE1   1 
ATOM   3331 O  OE2   . GLU A 1 444 ? 65.45300  21.63000  39.52300  1.000 293.05000 ? 444 GLU A OE2   1 
ATOM   3332 N  N     . ILE A 1 445 ? 62.70300  17.20800  38.89100  1.000 265.69000 ? 445 ILE A N     1 
ATOM   3333 C  CA    . ILE A 1 445 ? 62.37000  16.64800  40.18600  1.000 264.05000 ? 445 ILE A CA    1 
ATOM   3334 C  C     . ILE A 1 445 ? 63.15300  17.41300  41.23100  1.000 274.13000 ? 445 ILE A C     1 
ATOM   3335 O  O     . ILE A 1 445 ? 64.19900  16.93500  41.68200  1.000 274.75000 ? 445 ILE A O     1 
ATOM   3336 C  CB    . ILE A 1 445 ? 62.71300  15.15500  40.22600  1.000 268.98000 ? 445 ILE A CB    1 
ATOM   3337 C  CG1   . ILE A 1 445 ? 62.47600  14.55700  38.81600  1.000 267.97000 ? 445 ILE A CG1   1 
ATOM   3338 C  CG2   . ILE A 1 445 ? 61.94500  14.45400  41.36100  1.000 274.61000 ? 445 ILE A CG2   1 
ATOM   3339 C  CD1   . ILE A 1 445 ? 62.70200  13.08600  38.72700  1.000 272.64000 ? 445 ILE A CD1   1 
ATOM   3340 N  N     . ASN A 1 446 ? 62.68800  18.61300  41.59000  1.000 272.46000 ? 446 ASN A N     1 
ATOM   3341 C  CA    . ASN A 1 446 ? 63.45900  19.42100  42.52500  1.000 273.47000 ? 446 ASN A CA    1 
ATOM   3342 C  C     . ASN A 1 446 ? 63.69800  18.66900  43.82700  1.000 286.85000 ? 446 ASN A C     1 
ATOM   3343 O  O     . ASN A 1 446 ? 64.84000  18.56300  44.28400  1.000 295.03000 ? 446 ASN A O     1 
ATOM   3344 C  CB    . ASN A 1 446 ? 62.77900  20.75800  42.78000  1.000 279.93000 ? 446 ASN A CB    1 
ATOM   3345 C  CG    . ASN A 1 446 ? 63.68900  21.74300  43.53900  1.000 279.99000 ? 446 ASN A CG    1 
ATOM   3346 O  OD1   . ASN A 1 446 ? 63.37300  22.16300  44.67300  1.000 281.08000 ? 446 ASN A OD1   1 
ATOM   3347 N  ND2   . ASN A 1 446 ? 64.84000  22.07100  42.93800  1.000 285.30000 ? 446 ASN A ND2   1 
ATOM   3348 N  N     . LYS A 1 447 ? 62.64800  18.09200  44.42000  1.000 293.77000 ? 447 LYS A N     1 
ATOM   3349 C  CA    . LYS A 1 447 ? 62.80200  17.29600  45.64100  1.000 295.99000 ? 447 LYS A CA    1 
ATOM   3350 C  C     . LYS A 1 447 ? 62.18100  15.90700  45.46200  1.000 292.19000 ? 447 LYS A C     1 
ATOM   3351 O  O     . LYS A 1 447 ? 61.24200  15.71700  44.66800  1.000 289.50000 ? 447 LYS A O     1 
ATOM   3352 C  CB    . LYS A 1 447 ? 62.18400  17.98900  46.88200  1.000 291.97000 ? 447 LYS A CB    1 
ATOM   3353 C  CG    . LYS A 1 447 ? 62.72100  19.42100  47.25200  1.000 285.28000 ? 447 LYS A CG    1 
ATOM   3354 C  CD    . LYS A 1 447 ? 64.19300  19.43900  47.71700  1.000 287.40000 ? 447 LYS A CD    1 
ATOM   3355 C  CE    . LYS A 1 447 ? 64.75500  20.84900  47.62400  1.000 293.42000 ? 447 LYS A CE    1 
ATOM   3356 N  NZ    . LYS A 1 447 ? 66.22900  20.90100  47.75100  1.000 288.74000 ? 447 LYS A NZ    1 
ATOM   3357 N  N     . GLY A 1 448 ? 62.67600  14.94900  46.25500  1.000 294.64000 ? 448 GLY A N     1 
ATOM   3358 C  CA    . GLY A 1 448 ? 62.29800  13.56600  46.09300  1.000 283.80000 ? 448 GLY A CA    1 
ATOM   3359 C  C     . GLY A 1 448 ? 63.05800  12.94600  44.92800  1.000 287.69000 ? 448 GLY A C     1 
ATOM   3360 O  O     . GLY A 1 448 ? 63.76200  13.61600  44.15900  1.000 289.29000 ? 448 GLY A O     1 
ATOM   3361 N  N     . GLU A 1 449 ? 62.94400  11.62200  44.81500  1.000 288.72000 ? 449 GLU A N     1 
ATOM   3362 C  CA    . GLU A 1 449 ? 63.56800  10.88300  43.72000  1.000 286.92000 ? 449 GLU A CA    1 
ATOM   3363 C  C     . GLU A 1 449 ? 62.51200  10.08800  42.97700  1.000 281.68000 ? 449 GLU A C     1 
ATOM   3364 O  O     . GLU A 1 449 ? 61.55400  9.58800   43.57000  1.000 282.38000 ? 449 GLU A O     1 
ATOM   3365 C  CB    . GLU A 1 449 ? 64.67200  9.91500   44.18900  1.000 290.31000 ? 449 GLU A CB    1 
ATOM   3366 C  CG    . GLU A 1 449 ? 65.17100  8.95900   43.09300  1.000 292.73000 ? 449 GLU A CG    1 
ATOM   3367 C  CD    . GLU A 1 449 ? 65.57900  7.63200   43.63800  1.000 311.94000 ? 449 GLU A CD    1 
ATOM   3368 O  OE1   . GLU A 1 449 ? 66.78400  7.31400   43.57900  1.000 315.69000 ? 449 GLU A OE1   1 
ATOM   3369 O  OE2   . GLU A 1 449 ? 64.68400  6.90600   44.11700  1.000 318.34000 ? 449 GLU A OE2   1 
ATOM   3370 N  N     . ALA A 1 450 ? 62.69800  9.96400   41.67900  1.000 289.42000 ? 450 ALA A N     1 
ATOM   3371 C  CA    . ALA A 1 450 ? 61.76900  9.20200   40.86900  1.000 292.86000 ? 450 ALA A CA    1 
ATOM   3372 C  C     . ALA A 1 450 ? 62.43300  8.98000   39.52100  1.000 302.85000 ? 450 ALA A C     1 
ATOM   3373 O  O     . ALA A 1 450 ? 63.59300  9.35000   39.31000  1.000 300.67000 ? 450 ALA A O     1 
ATOM   3374 C  CB    . ALA A 1 450 ? 60.42100  9.92200   40.74100  1.000 285.78000 ? 450 ALA A CB    1 
ATOM   3375 N  N     . GLU A 1 451 ? 61.69100  8.34600   38.61700  1.000 312.01000 ? 451 GLU A N     1 
ATOM   3376 C  CA    . GLU A 1 451 ? 62.16200  8.10300   37.26000  1.000 306.97000 ? 451 GLU A CA    1 
ATOM   3377 C  C     . GLU A 1 451 ? 61.60100  9.19400   36.35100  1.000 297.62000 ? 451 GLU A C     1 
ATOM   3378 O  O     . GLU A 1 451 ? 60.40200  9.20600   36.04100  1.000 289.87000 ? 451 GLU A O     1 
ATOM   3379 C  CB    . GLU A 1 451 ? 61.75500  6.71500   36.78200  1.000 300.01000 ? 451 GLU A CB    1 
ATOM   3380 C  CG    . GLU A 1 451 ? 62.31300  6.36000   35.43700  1.000 298.45000 ? 451 GLU A CG    1 
ATOM   3381 C  CD    . GLU A 1 451 ? 61.79900  5.03300   34.95700  1.000 304.78000 ? 451 GLU A CD    1 
ATOM   3382 O  OE1   . GLU A 1 451 ? 61.25900  4.98700   33.84600  1.000 305.36000 ? 451 GLU A OE1   1 
ATOM   3383 O  OE2   . GLU A 1 451 ? 61.93200  4.03400   35.68600  1.000 309.76000 ? 451 GLU A OE2   1 
ATOM   3384 N  N     . ILE A 1 452 ? 62.48700  10.10700  35.93400  1.000 296.10000 ? 452 ILE A N     1 
ATOM   3385 C  CA    . ILE A 1 452 ? 62.15500  11.24600  35.08000  1.000 287.46000 ? 452 ILE A CA    1 
ATOM   3386 C  C     . ILE A 1 452 ? 61.31400  10.84300  33.88000  1.000 279.57000 ? 452 ILE A C     1 
ATOM   3387 O  O     . ILE A 1 452 ? 60.45400  11.60300  33.41100  1.000 276.97000 ? 452 ILE A O     1 
ATOM   3388 C  CB    . ILE A 1 452 ? 63.45800  11.91700  34.62900  1.000 289.47000 ? 452 ILE A CB    1 
ATOM   3389 C  CG1   . ILE A 1 452 ? 63.12300  13.11200  33.76300  1.000 289.38000 ? 452 ILE A CG1   1 
ATOM   3390 C  CG2   . ILE A 1 452 ? 64.34400  10.91900  33.88700  1.000 287.14000 ? 452 ILE A CG2   1 
ATOM   3391 C  CD1   . ILE A 1 452 ? 62.32200  14.14300  34.50300  1.000 289.84000 ? 452 ILE A CD1   1 
ATOM   3392 N  N     . GLN A 1 453 ? 61.58700  9.67100   33.32700  1.000 280.15000 ? 453 GLN A N     1 
ATOM   3393 C  CA    . GLN A 1 453 ? 60.75800  9.18200   32.24900  1.000 277.28000 ? 453 GLN A CA    1 
ATOM   3394 C  C     . GLN A 1 453 ? 59.31600  9.03000   32.69400  1.000 272.48000 ? 453 GLN A C     1 
ATOM   3395 O  O     . GLN A 1 453 ? 58.40600  9.48900   31.99600  1.000 274.31000 ? 453 GLN A O     1 
ATOM   3396 C  CB    . GLN A 1 453 ? 61.32400  7.87500   31.74200  1.000 281.89000 ? 453 GLN A CB    1 
ATOM   3397 C  CG    . GLN A 1 453 ? 62.66600  8.05900   31.11700  1.000 282.85000 ? 453 GLN A CG    1 
ATOM   3398 C  CD    . GLN A 1 453 ? 62.70900  7.37300   29.78700  1.000 282.30000 ? 453 GLN A CD    1 
ATOM   3399 O  OE1   . GLN A 1 453 ? 61.74300  6.72100   29.39200  1.000 282.94000 ? 453 GLN A OE1   1 
ATOM   3400 N  NE2   . GLN A 1 453 ? 63.82400  7.49800   29.08400  1.000 283.72000 ? 453 GLN A NE2   1 
ATOM   3401 N  N     . GLN A 1 454 ? 59.08200  8.42200   33.85600  1.000 282.97000 ? 454 GLN A N     1 
ATOM   3402 C  CA    . GLN A 1 454 ? 57.72000  8.38500   34.36300  1.000 280.76000 ? 454 GLN A CA    1 
ATOM   3403 C  C     . GLN A 1 454 ? 57.18300  9.79500   34.53600  1.000 280.88000 ? 454 GLN A C     1 
ATOM   3404 O  O     . GLN A 1 454 ? 56.06300  10.10500  34.10800  1.000 279.40000 ? 454 GLN A O     1 
ATOM   3405 C  CB    . GLN A 1 454 ? 57.67600  7.61900   35.68200  1.000 277.51000 ? 454 GLN A CB    1 
ATOM   3406 C  CG    . GLN A 1 454 ? 56.29500  7.08100   36.01000  1.000 285.79000 ? 454 GLN A CG    1 
ATOM   3407 C  CD    . GLN A 1 454 ? 55.70800  6.24500   34.86800  1.000 294.26000 ? 454 GLN A CD    1 
ATOM   3408 O  OE1   . GLN A 1 454 ? 56.36300  5.33000   34.36100  1.000 291.09000 ? 454 GLN A OE1   1 
ATOM   3409 N  NE2   . GLN A 1 454 ? 54.48000  6.57500   34.44400  1.000 299.49000 ? 454 GLN A NE2   1 
ATOM   3410 N  N     . VAL A 1 455 ? 57.99700  10.67000  35.11700  1.000 282.14000 ? 455 VAL A N     1 
ATOM   3411 C  CA    . VAL A 1 455 ? 57.58900  12.05200  35.34000  1.000 286.66000 ? 455 VAL A CA    1 
ATOM   3412 C  C     . VAL A 1 455 ? 57.10500  12.68200  34.04300  1.000 278.50000 ? 455 VAL A C     1 
ATOM   3413 O  O     . VAL A 1 455 ? 55.95500  13.12800  33.93300  1.000 274.54000 ? 455 VAL A O     1 
ATOM   3414 C  CB    . VAL A 1 455 ? 58.75000  12.85200  35.94800  1.000 301.09000 ? 455 VAL A CB    1 
ATOM   3415 C  CG1   . VAL A 1 455 ? 58.42200  14.33100  35.94300  1.000 304.94000 ? 455 VAL A CG1   1 
ATOM   3416 C  CG2   . VAL A 1 455 ? 59.01200  12.36400  37.35800  1.000 305.03000 ? 455 VAL A CG2   1 
ATOM   3417 N  N     . LEU A 1 456 ? 57.99600  12.75600  33.05700  1.000 273.63000 ? 456 LEU A N     1 
ATOM   3418 C  CA    . LEU A 1 456 ? 57.60300  13.20100  31.73100  1.000 272.55000 ? 456 LEU A CA    1 
ATOM   3419 C  C     . LEU A 1 456 ? 56.26900  12.57900  31.31700  1.000 269.70000 ? 456 LEU A C     1 
ATOM   3420 O  O     . LEU A 1 456 ? 55.30800  13.29500  31.00500  1.000 265.96000 ? 456 LEU A O     1 
ATOM   3421 C  CB    . LEU A 1 456 ? 58.71800  12.86000  30.75000  1.000 269.10000 ? 456 LEU A CB    1 
ATOM   3422 C  CG    . LEU A 1 456 ? 60.05400  13.53600  31.02900  1.000 267.06000 ? 456 LEU A CG    1 
ATOM   3423 C  CD1   . LEU A 1 456 ? 61.09600  13.14700  29.94500  1.000 270.53000 ? 456 LEU A CD1   1 
ATOM   3424 C  CD2   . LEU A 1 456 ? 59.91000  15.06000  31.23100  1.000 270.88000 ? 456 LEU A CD2   1 
ATOM   3425 N  N     . LYS A 1 457 ? 56.17600  11.24600  31.37200  1.000 267.99000 ? 457 LYS A N     1 
ATOM   3426 C  CA    . LYS A 1 457 ? 54.95500  10.54700  30.98200  1.000 262.18000 ? 457 LYS A CA    1 
ATOM   3427 C  C     . LYS A 1 457 ? 53.74600  11.09900  31.70200  1.000 260.55000 ? 457 LYS A C     1 
ATOM   3428 O  O     . LYS A 1 457 ? 52.83200  11.64500  31.08500  1.000 260.18000 ? 457 LYS A O     1 
ATOM   3429 C  CB    . LYS A 1 457 ? 55.07000  9.05900   31.28800  1.000 264.93000 ? 457 LYS A CB    1 
ATOM   3430 C  CG    . LYS A 1 457 ? 55.97400  8.33500   30.36100  1.000 267.67000 ? 457 LYS A CG    1 
ATOM   3431 C  CD    . LYS A 1 457 ? 55.60500  6.87500   30.26400  1.000 273.04000 ? 457 LYS A CD    1 
ATOM   3432 C  CE    . LYS A 1 457 ? 56.12400  6.34000   28.94700  1.000 285.77000 ? 457 LYS A CE    1 
ATOM   3433 N  NZ    . LYS A 1 457 ? 56.15700  4.86000   28.85200  1.000 291.52000 ? 457 LYS A NZ    1 
ATOM   3434 N  N     . ASP A 1 458 ? 53.69900  10.88200  33.01000  1.000 267.20000 ? 458 ASP A N     1 
ATOM   3435 C  CA    . ASP A 1 458 ? 52.65000  11.47300  33.82400  1.000 267.79000 ? 458 ASP A CA    1 
ATOM   3436 C  C     . ASP A 1 458 ? 52.32800  12.87900  33.37600  1.000 268.09000 ? 458 ASP A C     1 
ATOM   3437 O  O     . ASP A 1 458 ? 51.16700  13.20000  33.11900  1.000 269.02000 ? 458 ASP A O     1 
ATOM   3438 C  CB    . ASP A 1 458 ? 53.07800  11.48800  35.29000  1.000 275.89000 ? 458 ASP A CB    1 
ATOM   3439 C  CG    . ASP A 1 458 ? 53.36600  10.11800  35.80200  1.000 281.33000 ? 458 ASP A CG    1 
ATOM   3440 O  OD1   . ASP A 1 458 ? 53.31400  9.18900   34.96300  1.000 286.61000 ? 458 ASP A OD1   1 
ATOM   3441 O  OD2   . ASP A 1 458 ? 53.62500  9.97600   37.01600  1.000 282.62000 ? 458 ASP A OD2   1 
ATOM   3442 N  N     . ILE A 1 459 ? 53.33000  13.73100  33.25500  1.000 264.30000 ? 459 ILE A N     1 
ATOM   3443 C  CA    . ILE A 1 459 ? 53.00600  15.11900  32.99200  1.000 264.47000 ? 459 ILE A CA    1 
ATOM   3444 C  C     . ILE A 1 459 ? 52.40400  15.27400  31.61400  1.000 262.69000 ? 459 ILE A C     1 
ATOM   3445 O  O     . ILE A 1 459 ? 51.42800  16.01300  31.42600  1.000 261.95000 ? 459 ILE A O     1 
ATOM   3446 C  CB    . ILE A 1 459 ? 54.24100  15.99500  33.17400  1.000 266.28000 ? 459 ILE A CB    1 
ATOM   3447 C  CG1   . ILE A 1 459 ? 54.42800  16.25000  34.66200  1.000 269.11000 ? 459 ILE A CG1   1 
ATOM   3448 C  CG2   . ILE A 1 459 ? 54.03800  17.28000  32.44800  1.000 267.76000 ? 459 ILE A CG2   1 
ATOM   3449 C  CD1   . ILE A 1 459 ? 55.72900  16.87600  34.98400  1.000 277.70000 ? 459 ILE A CD1   1 
ATOM   3450 N  N     . LEU A 1 460 ? 52.96400  14.57400  30.63500  1.000 259.58000 ? 460 LEU A N     1 
ATOM   3451 C  CA    . LEU A 1 460 ? 52.28100  14.52800  29.36100  1.000 260.15000 ? 460 LEU A CA    1 
ATOM   3452 C  C     . LEU A 1 460 ? 50.86900  14.02300  29.55800  1.000 261.38000 ? 460 LEU A C     1 
ATOM   3453 O  O     . LEU A 1 460 ? 49.94000  14.48500  28.88900  1.000 263.94000 ? 460 LEU A O     1 
ATOM   3454 C  CB    . LEU A 1 460 ? 53.03400  13.65800  28.36900  1.000 259.83000 ? 460 LEU A CB    1 
ATOM   3455 C  CG    . LEU A 1 460 ? 52.60700  14.10500  26.95900  1.000 263.50000 ? 460 LEU A CG    1 
ATOM   3456 C  CD1   . LEU A 1 460 ? 53.10900  15.52500  26.66100  1.000 266.96000 ? 460 LEU A CD1   1 
ATOM   3457 C  CD2   . LEU A 1 460 ? 53.01900  13.13200  25.86300  1.000 274.11000 ? 460 LEU A CD2   1 
ATOM   3458 N  N     . ALA A 1 461 ? 50.67600  13.11700  30.51600  1.000 265.69000 ? 461 ALA A N     1 
ATOM   3459 C  CA    . ALA A 1 461 ? 49.32900  12.62300  30.77700  1.000 265.52000 ? 461 ALA A CA    1 
ATOM   3460 C  C     . ALA A 1 461 ? 48.43800  13.72700  31.33000  1.000 263.42000 ? 461 ALA A C     1 
ATOM   3461 O  O     . ALA A 1 461 ? 47.23700  13.78200  31.04200  1.000 262.95000 ? 461 ALA A O     1 
ATOM   3462 C  CB    . ALA A 1 461 ? 49.37600  11.44200  31.74200  1.000 267.56000 ? 461 ALA A CB    1 
ATOM   3463 N  N     . LEU A 1 462 ? 49.01100  14.63000  32.11400  1.000 257.17000 ? 462 LEU A N     1 
ATOM   3464 C  CA    . LEU A 1 462 ? 48.16500  15.56000  32.83900  1.000 257.63000 ? 462 LEU A CA    1 
ATOM   3465 C  C     . LEU A 1 462 ? 47.66700  16.69700  31.97700  1.000 257.94000 ? 462 LEU A C     1 
ATOM   3466 O  O     . LEU A 1 462 ? 46.64600  17.30500  32.30100  1.000 256.99000 ? 462 LEU A O     1 
ATOM   3467 C  CB    . LEU A 1 462 ? 48.91500  16.09500  34.04500  1.000 262.80000 ? 462 LEU A CB    1 
ATOM   3468 C  CG    . LEU A 1 462 ? 48.99500  15.07100  35.18500  1.000 277.40000 ? 462 LEU A CG    1 
ATOM   3469 C  CD1   . LEU A 1 462 ? 50.03500  15.45800  36.24300  1.000 278.62000 ? 462 LEU A CD1   1 
ATOM   3470 C  CD2   . LEU A 1 462 ? 47.62300  14.89600  35.82000  1.000 282.97000 ? 462 LEU A CD2   1 
ATOM   3471 N  N     . THR A 1 463 ? 48.31800  16.97600  30.87000  1.000 259.90000 ? 463 THR A N     1 
ATOM   3472 C  CA    . THR A 1 463 ? 47.76100  17.99600  29.99900  1.000 260.45000 ? 463 THR A CA    1 
ATOM   3473 C  C     . THR A 1 463 ? 46.40600  17.59500  29.44400  1.000 260.24000 ? 463 THR A C     1 
ATOM   3474 O  O     . THR A 1 463 ? 45.62200  18.46100  29.03800  1.000 262.45000 ? 463 THR A O     1 
ATOM   3475 C  CB    . THR A 1 463 ? 48.73000  18.27900  28.85500  1.000 263.60000 ? 463 THR A CB    1 
ATOM   3476 O  OG1   . THR A 1 463 ? 48.57700  17.27200  27.85400  1.000 264.60000 ? 463 THR A OG1   1 
ATOM   3477 C  CG2   . THR A 1 463 ? 50.14700  18.22300  29.37300  1.000 268.30000 ? 463 THR A CG2   1 
ATOM   3478 N  N     . LYS A 1 464 ? 46.12300  16.30400  29.42100  1.000 259.79000 ? 464 LYS A N     1 
ATOM   3479 C  CA    . LYS A 1 464 ? 44.94600  15.77500  28.76300  1.000 260.45000 ? 464 LYS A CA    1 
ATOM   3480 C  C     . LYS A 1 464 ? 43.68700  15.92100  29.57900  1.000 260.61000 ? 464 LYS A C     1 
ATOM   3481 O  O     . LYS A 1 464 ? 42.61800  15.57500  29.08400  1.000 264.87000 ? 464 LYS A O     1 
ATOM   3482 C  CB    . LYS A 1 464 ? 45.13900  14.29500  28.45600  1.000 262.49000 ? 464 LYS A CB    1 
ATOM   3483 C  CG    . LYS A 1 464 ? 45.92600  14.00700  27.22300  1.000 266.69000 ? 464 LYS A CG    1 
ATOM   3484 C  CD    . LYS A 1 464 ? 45.05600  13.96600  25.98800  1.000 267.51000 ? 464 LYS A CD    1 
ATOM   3485 C  CE    . LYS A 1 464 ? 45.90500  13.60100  24.79200  1.000 267.41000 ? 464 LYS A CE    1 
ATOM   3486 N  NZ    . LYS A 1 464 ? 47.13800  14.43200  24.84100  1.000 272.98000 ? 464 LYS A NZ    1 
ATOM   3487 N  N     . LEU A 1 465 ? 43.77500  16.39900  30.81000  1.000 257.88000 ? 465 LEU A N     1 
ATOM   3488 C  CA    . LEU A 1 465 ? 42.66700  16.24300  31.73000  1.000 260.24000 ? 465 LEU A CA    1 
ATOM   3489 C  C     . LEU A 1 465 ? 41.83000  17.49900  31.84800  1.000 264.77000 ? 465 LEU A C     1 
ATOM   3490 O  O     . LEU A 1 465 ? 40.87000  17.52200  32.62700  1.000 268.91000 ? 465 LEU A O     1 
ATOM   3491 C  CB    . LEU A 1 465 ? 43.19300  15.78700  33.09700  1.000 261.04000 ? 465 LEU A CB    1 
ATOM   3492 C  CG    . LEU A 1 465 ? 43.74300  14.35700  33.03000  1.000 258.68000 ? 465 LEU A CG    1 
ATOM   3493 C  CD1   . LEU A 1 465 ? 44.36300  13.94400  34.33600  1.000 271.48000 ? 465 LEU A CD1   1 
ATOM   3494 C  CD2   . LEU A 1 465 ? 42.63900  13.38900  32.67000  1.000 260.61000 ? 465 LEU A CD2   1 
ATOM   3495 N  N     . ASN A 1 466 ? 42.14500  18.53100  31.07700  1.000 266.91000 ? 466 ASN A N     1 
ATOM   3496 C  CA    . ASN A 1 466 ? 41.43400  19.79700  31.22600  1.000 263.49000 ? 466 ASN A CA    1 
ATOM   3497 C  C     . ASN A 1 466 ? 40.03200  19.67400  30.64200  1.000 264.36000 ? 466 ASN A C     1 
ATOM   3498 O  O     . ASN A 1 466 ? 39.84700  19.80300  29.42700  1.000 265.83000 ? 466 ASN A O     1 
ATOM   3499 C  CB    . ASN A 1 466 ? 42.19400  20.92900  30.55700  1.000 266.55000 ? 466 ASN A CB    1 
ATOM   3500 C  CG    . ASN A 1 466 ? 41.46800  22.24700  30.69300  1.000 267.81000 ? 466 ASN A CG    1 
ATOM   3501 O  OD1   . ASN A 1 466 ? 40.37100  22.32300  31.24600  1.000 271.27000 ? 466 ASN A OD1   1 
ATOM   3502 N  ND2   . ASN A 1 466 ? 42.07600  23.29600  30.20200  1.000 269.95000 ? 466 ASN A ND2   1 
ATOM   3503 N  N     . TYR A 1 467 ? 39.03200  19.46900  31.51300  1.000 265.64000 ? 467 TYR A N     1 
ATOM   3504 C  CA    . TYR A 1 467 ? 37.66300  19.27300  31.03000  1.000 267.82000 ? 467 TYR A CA    1 
ATOM   3505 C  C     . TYR A 1 467 ? 37.06000  20.54000  30.45100  1.000 268.29000 ? 467 TYR A C     1 
ATOM   3506 O  O     . TYR A 1 467 ? 36.10900  20.47800  29.66300  1.000 268.95000 ? 467 TYR A O     1 
ATOM   3507 C  CB    . TYR A 1 467 ? 36.75800  18.76900  32.14700  1.000 270.22000 ? 467 TYR A CB    1 
ATOM   3508 C  CG    . TYR A 1 467 ? 37.07600  17.37800  32.56200  1.000 274.39000 ? 467 TYR A CG    1 
ATOM   3509 C  CD1   . TYR A 1 467 ? 37.42000  16.42500  31.61600  1.000 275.77000 ? 467 TYR A CD1   1 
ATOM   3510 C  CD2   . TYR A 1 467 ? 37.08300  17.02800  33.90900  1.000 274.89000 ? 467 TYR A CD2   1 
ATOM   3511 C  CE1   . TYR A 1 467 ? 37.74300  15.15700  31.98100  1.000 275.87000 ? 467 TYR A CE1   1 
ATOM   3512 C  CE2   . TYR A 1 467 ? 37.40800  15.76600  34.29600  1.000 277.53000 ? 467 TYR A CE2   1 
ATOM   3513 C  CZ    . TYR A 1 467 ? 37.73500  14.82700  33.33500  1.000 277.96000 ? 467 TYR A CZ    1 
ATOM   3514 O  OH    . TYR A 1 467 ? 38.06000  13.55600  33.74500  1.000 278.39000 ? 467 TYR A OH    1 
ATOM   3515 N  N     . ASN A 1 468 ? 37.57100  21.69700  30.84400  1.000 270.09000 ? 468 ASN A N     1 
ATOM   3516 C  CA    . ASN A 1 468 ? 36.86700  22.92400  30.51000  1.000 274.31000 ? 468 ASN A CA    1 
ATOM   3517 C  C     . ASN A 1 468 ? 37.20900  23.40800  29.12100  1.000 276.33000 ? 468 ASN A C     1 
ATOM   3518 O  O     . ASN A 1 468 ? 36.31200  23.70700  28.32200  1.000 288.20000 ? 468 ASN A O     1 
ATOM   3519 C  CB    . ASN A 1 468 ? 37.17500  24.00100  31.51600  1.000 274.19000 ? 468 ASN A CB    1 
ATOM   3520 C  CG    . ASN A 1 468 ? 36.18600  24.01800  32.62800  1.000 283.76000 ? 468 ASN A CG    1 
ATOM   3521 O  OD1   . ASN A 1 468 ? 35.15100  24.67500  32.55800  1.000 280.99000 ? 468 ASN A OD1   1 
ATOM   3522 N  ND2   . ASN A 1 468 ? 36.49500  23.27700  33.65500  1.000 293.01000 ? 468 ASN A ND2   1 
ATOM   3523 N  N     . ALA A 1 469 ? 38.49000  23.46600  28.80800  1.000 279.19000 ? 469 ALA A N     1 
ATOM   3524 C  CA    . ALA A 1 469 ? 38.95100  23.82500  27.48300  1.000 287.70000 ? 469 ALA A CA    1 
ATOM   3525 C  C     . ALA A 1 469 ? 39.15700  22.48400  26.81000  1.000 287.51000 ? 469 ALA A C     1 
ATOM   3526 O  O     . ALA A 1 469 ? 40.17400  21.82500  27.04900  1.000 286.41000 ? 469 ALA A O     1 
ATOM   3527 C  CB    . ALA A 1 469 ? 40.22900  24.66500  27.53500  1.000 286.85000 ? 469 ALA A CB    1 
ATOM   3528 N  N     . CYS A 1 470 ? 38.15000  22.02800  26.06700  1.000 289.85000 ? 470 CYS A N     1 
ATOM   3529 C  CA    . CYS A 1 470 ? 38.21200  20.72600  25.41500  1.000 280.24000 ? 470 CYS A CA    1 
ATOM   3530 C  C     . CYS A 1 470 ? 39.11200  20.83200  24.20000  1.000 276.89000 ? 470 CYS A C     1 
ATOM   3531 O  O     . CYS A 1 470 ? 38.66700  21.26300  23.13200  1.000 279.48000 ? 470 CYS A O     1 
ATOM   3532 C  CB    . CYS A 1 470 ? 36.83700  20.22900  24.98800  1.000 273.78000 ? 470 CYS A CB    1 
ATOM   3533 S  SG    . CYS A 1 470 ? 36.98600  18.69700  24.08600  1.000 273.58000 ? 470 CYS A SG    1 
ATOM   3534 N  N     . ILE A 1 471 ? 40.36600  20.42700  24.35600  1.000 275.82000 ? 471 ILE A N     1 
ATOM   3535 C  CA    . ILE A 1 471 ? 41.30600  20.36900  23.25300  1.000 278.06000 ? 471 ILE A CA    1 
ATOM   3536 C  C     . ILE A 1 471 ? 42.03800  19.04300  23.32500  1.000 277.84000 ? 471 ILE A C     1 
ATOM   3537 O  O     . ILE A 1 471 ? 41.89600  18.28100  24.28200  1.000 278.56000 ? 471 ILE A O     1 
ATOM   3538 C  CB    . ILE A 1 471 ? 42.33600  21.50900  23.29300  1.000 276.64000 ? 471 ILE A CB    1 
ATOM   3539 C  CG1   . ILE A 1 471 ? 42.88100  21.63700  24.71400  1.000 276.45000 ? 471 ILE A CG1   1 
ATOM   3540 C  CG2   . ILE A 1 471 ? 41.71900  22.80400  22.80800  1.000 284.07000 ? 471 ILE A CG2   1 
ATOM   3541 C  CD1   . ILE A 1 471 ? 44.00600  22.60200  24.79700  1.000 281.77000 ? 471 ILE A CD1   1 
ATOM   3542 N  N     . TYR A 1 472 ? 42.84700  18.79500  22.28500  1.000 274.05000 ? 472 TYR A N     1 
ATOM   3543 C  CA    . TYR A 1 472 ? 43.69200  17.59800  22.22400  1.000 273.45000 ? 472 TYR A CA    1 
ATOM   3544 C  C     . TYR A 1 472 ? 44.52200  17.46700  23.48400  1.000 276.24000 ? 472 TYR A C     1 
ATOM   3545 O  O     . TYR A 1 472 ? 44.52500  16.42000  24.14600  1.000 282.70000 ? 472 TYR A O     1 
ATOM   3546 C  CB    . TYR A 1 472 ? 44.62000  17.64400  21.01000  1.000 268.10000 ? 472 TYR A CB    1 
ATOM   3547 C  CG    . TYR A 1 472 ? 45.39700  16.38400  20.71700  1.000 272.39000 ? 472 TYR A CG    1 
ATOM   3548 C  CD1   . TYR A 1 472 ? 46.65900  16.16400  21.26900  1.000 272.08000 ? 472 TYR A CD1   1 
ATOM   3549 C  CD2   . TYR A 1 472 ? 44.86000  15.40200  19.89100  1.000 279.46000 ? 472 TYR A CD2   1 
ATOM   3550 C  CE1   . TYR A 1 472 ? 47.37000  14.99200  20.99300  1.000 273.37000 ? 472 TYR A CE1   1 
ATOM   3551 C  CE2   . TYR A 1 472 ? 45.56300  14.23500  19.61600  1.000 280.16000 ? 472 TYR A CE2   1 
ATOM   3552 C  CZ    . TYR A 1 472 ? 46.81700  14.03900  20.16300  1.000 275.23000 ? 472 TYR A CZ    1 
ATOM   3553 O  OH    . TYR A 1 472 ? 47.52700  12.88800  19.88400  1.000 283.25000 ? 472 TYR A OH    1 
ATOM   3554 N  N     . ALA A 1 473 ? 45.19200  18.54500  23.86300  1.000 271.82000 ? 473 ALA A N     1 
ATOM   3555 C  CA    . ALA A 1 473 ? 45.97000  18.55300  25.09200  1.000 270.36000 ? 473 ALA A CA    1 
ATOM   3556 C  C     . ALA A 1 473 ? 46.33100  19.98600  25.37200  1.000 269.90000 ? 473 ALA A C     1 
ATOM   3557 O  O     . ALA A 1 473 ? 46.40800  20.80300  24.45700  1.000 270.71000 ? 473 ALA A O     1 
ATOM   3558 C  CB    . ALA A 1 473 ? 47.23400  17.70900  24.99100  1.000 272.12000 ? 473 ALA A CB    1 
ATOM   3559 N  N     . ASP A 1 474 ? 46.56800  20.27900  26.63100  1.000 269.57000 ? 474 ASP A N     1 
ATOM   3560 C  CA    . ASP A 1 474 ? 46.97500  21.63200  26.93400  1.000 277.20000 ? 474 ASP A CA    1 
ATOM   3561 C  C     . ASP A 1 474 ? 48.49600  21.77500  26.92200  1.000 272.21000 ? 474 ASP A C     1 
ATOM   3562 O  O     . ASP A 1 474 ? 49.24600  20.80200  26.81100  1.000 267.67000 ? 474 ASP A O     1 
ATOM   3563 C  CB    . ASP A 1 474 ? 46.39300  22.04900  28.27700  1.000 292.85000 ? 474 ASP A CB    1 
ATOM   3564 C  CG    . ASP A 1 474 ? 45.86400  23.47100  28.25700  1.000 307.81000 ? 474 ASP A CG    1 
ATOM   3565 O  OD1   . ASP A 1 474 ? 46.67500  24.40600  28.02100  1.000 311.46000 ? 474 ASP A OD1   1 
ATOM   3566 O  OD2   . ASP A 1 474 ? 44.63100  23.65500  28.43700  1.000 316.20000 ? 474 ASP A OD2   1 
ATOM   3567 N  N     . GLY A 1 475 ? 48.94600  23.02700  26.98700  1.000 274.23000 ? 475 GLY A N     1 
ATOM   3568 C  CA    . GLY A 1 475 ? 50.37000  23.27300  27.10100  1.000 268.40000 ? 475 GLY A CA    1 
ATOM   3569 C  C     . GLY A 1 475 ? 50.92700  22.82300  28.43500  1.000 269.05000 ? 475 GLY A C     1 
ATOM   3570 O  O     . GLY A 1 475 ? 52.04300  22.30300  28.51000  1.000 271.22000 ? 475 GLY A O     1 
ATOM   3571 N  N     . GLU A 1 476 ? 50.09100  22.99900  29.57200  1.000 280.83000 ? 476 GLU A N     1 
ATOM   3572 C  CA    . GLU A 1 476 ? 50.37400  22.73900  30.98000  1.000 282.66000 ? 476 GLU A CA    1 
ATOM   3573 C  C     . GLU A 1 476 ? 49.61600  21.52500  31.48900  1.000 274.52000 ? 476 GLU A C     1 
ATOM   3574 O  O     . GLU A 1 476 ? 48.47900  21.27200  31.08600  1.000 275.24000 ? 476 GLU A O     1 
ATOM   3575 C  CB    . GLU A 1 476 ? 49.97600  23.92500  31.84500  1.000 287.88000 ? 476 GLU A CB    1 
ATOM   3576 C  CG    . GLU A 1 476 ? 51.11900  24.66800  32.48300  1.000 296.65000 ? 476 GLU A CG    1 
ATOM   3577 C  CD    . GLU A 1 476 ? 50.88900  26.12500  32.19500  1.000 315.66000 ? 476 GLU A CD    1 
ATOM   3578 O  OE1   . GLU A 1 476 ? 50.15700  26.36600  31.21000  1.000 313.82000 ? 476 GLU A OE1   1 
ATOM   3579 O  OE2   . GLU A 1 476 ? 51.46500  26.98100  32.87300  1.000 335.09000 ? 476 GLU A OE2   1 
ATOM   3580 N  N     . PRO A 1 477 ? 50.21200  20.75500  32.38400  1.000 267.51000 ? 477 PRO A N     1 
ATOM   3581 C  CA    . PRO A 1 477 ? 49.42400  19.77800  33.12200  1.000 261.70000 ? 477 PRO A CA    1 
ATOM   3582 C  C     . PRO A 1 477 ? 48.48300  20.51800  34.05300  1.000 268.30000 ? 477 PRO A C     1 
ATOM   3583 O  O     . PRO A 1 477 ? 48.82000  21.57200  34.59700  1.000 270.40000 ? 477 PRO A O     1 
ATOM   3584 C  CB    . PRO A 1 477 ? 50.48000  18.97600  33.88000  1.000 260.79000 ? 477 PRO A CB    1 
ATOM   3585 C  CG    . PRO A 1 477 ? 51.57600  19.88900  34.02300  1.000 267.78000 ? 477 PRO A CG    1 
ATOM   3586 C  CD    . PRO A 1 477 ? 51.61400  20.75500  32.81000  1.000 269.65000 ? 477 PRO A CD    1 
ATOM   3587 N  N     . VAL A 1 478 ? 47.27800  19.97500  34.18700  1.000 276.63000 ? 478 VAL A N     1 
ATOM   3588 C  CA    . VAL A 1 478 ? 46.14400  20.59300  34.87300  1.000 282.62000 ? 478 VAL A CA    1 
ATOM   3589 C  C     . VAL A 1 478 ? 46.46100  20.92600  36.32100  1.000 278.54000 ? 478 VAL A C     1 
ATOM   3590 O  O     . VAL A 1 478 ? 45.81400  21.79700  36.92400  1.000 275.21000 ? 478 VAL A O     1 
ATOM   3591 C  CB    . VAL A 1 478 ? 44.92000  19.66800  34.81800  1.000 289.94000 ? 478 VAL A CB    1 
ATOM   3592 C  CG1   . VAL A 1 478 ? 45.13400  18.47000  35.73000  1.000 293.16000 ? 478 VAL A CG1   1 
ATOM   3593 C  CG2   . VAL A 1 478 ? 43.64900  20.42900  35.19200  1.000 287.75000 ? 478 VAL A CG2   1 
ATOM   3594 N  N     . THR A 1 479 ? 47.40900  20.18300  36.90100  1.000 278.56000 ? 479 THR A N     1 
ATOM   3595 C  CA    . THR A 1 479 ? 47.90900  20.51900  38.22100  1.000 275.22000 ? 479 THR A CA    1 
ATOM   3596 C  C     . THR A 1 479 ? 48.16300  22.01100  38.30000  1.000 279.92000 ? 479 THR A C     1 
ATOM   3597 O  O     . THR A 1 479 ? 47.51500  22.71900  39.06500  1.000 283.48000 ? 479 THR A O     1 
ATOM   3598 C  CB    . THR A 1 479 ? 49.16600  19.70400  38.52700  1.000 271.61000 ? 479 THR A CB    1 
ATOM   3599 O  OG1   . THR A 1 479 ? 50.02800  19.72200  37.38600  1.000 273.34000 ? 479 THR A OG1   1 
ATOM   3600 C  CG2   . THR A 1 479 ? 48.79200  18.27300  38.79800  1.000 268.38000 ? 479 THR A CG2   1 
ATOM   3601 N  N     . LEU A 1 480 ? 49.00900  22.52400  37.42600  1.000 277.22000 ? 480 LEU A N     1 
ATOM   3602 C  CA    . LEU A 1 480 ? 49.34100  23.93500  37.44000  1.000 284.66000 ? 480 LEU A CA    1 
ATOM   3603 C  C     . LEU A 1 480 ? 48.58300  24.73700  36.40000  1.000 283.45000 ? 480 LEU A C     1 
ATOM   3604 O  O     . LEU A 1 480 ? 48.72000  25.96700  36.38100  1.000 287.93000 ? 480 LEU A O     1 
ATOM   3605 C  CB    . LEU A 1 480 ? 50.84700  24.13100  37.22000  1.000 290.70000 ? 480 LEU A CB    1 
ATOM   3606 C  CG    . LEU A 1 480 ? 51.84300  23.10300  37.75500  1.000 287.35000 ? 480 LEU A CG    1 
ATOM   3607 C  CD1   . LEU A 1 480 ? 53.13000  23.28300  36.99200  1.000 288.24000 ? 480 LEU A CD1   1 
ATOM   3608 C  CD2   . LEU A 1 480 ? 52.06100  23.30300  39.24200  1.000 279.70000 ? 480 LEU A CD2   1 
ATOM   3609 N  N     . ARG A 1 481 ? 47.80200  24.08700  35.53400  1.000 275.68000 ? 481 ARG A N     1 
ATOM   3610 C  CA    . ARG A 1 481 ? 47.14200  24.84100  34.47700  1.000 276.22000 ? 481 ARG A CA    1 
ATOM   3611 C  C     . ARG A 1 481 ? 46.29600  25.97400  35.04100  1.000 275.10000 ? 481 ARG A C     1 
ATOM   3612 O  O     . ARG A 1 481 ? 46.36000  27.11000  34.55800  1.000 281.80000 ? 481 ARG A O     1 
ATOM   3613 C  CB    . ARG A 1 481 ? 46.30100  23.90000  33.61700  1.000 273.45000 ? 481 ARG A CB    1 
ATOM   3614 C  CG    . ARG A 1 481 ? 45.22600  24.56800  32.77800  1.000 276.45000 ? 481 ARG A CG    1 
ATOM   3615 C  CD    . ARG A 1 481 ? 45.74400  25.12400  31.46900  1.000 283.27000 ? 481 ARG A CD    1 
ATOM   3616 N  NE    . ARG A 1 481 ? 44.62500  25.43600  30.58900  1.000 283.96000 ? 481 ARG A NE    1 
ATOM   3617 C  CZ    . ARG A 1 481 ? 44.04500  26.62500  30.50100  1.000 292.21000 ? 481 ARG A CZ    1 
ATOM   3618 N  NH1   . ARG A 1 481 ? 44.48900  27.63900  31.23000  1.000 298.62000 ? 481 ARG A NH1   1 
ATOM   3619 N  NH2   . ARG A 1 481 ? 43.02100  26.80000  29.67600  1.000 295.50000 ? 481 ARG A NH2   1 
ATOM   3620 N  N     . PHE A 1 482 ? 45.54200  25.71500  36.09200  1.000 268.82000 ? 482 PHE A N     1 
ATOM   3621 C  CA    . PHE A 1 482 ? 44.50900  26.66000  36.46900  1.000 278.27000 ? 482 PHE A CA    1 
ATOM   3622 C  C     . PHE A 1 482 ? 44.91700  27.58500  37.58800  1.000 285.51000 ? 482 PHE A C     1 
ATOM   3623 O  O     . PHE A 1 482 ? 44.09900  28.39500  38.03700  1.000 286.83000 ? 482 PHE A O     1 
ATOM   3624 C  CB    . PHE A 1 482 ? 43.23800  25.89200  36.78600  1.000 279.50000 ? 482 PHE A CB    1 
ATOM   3625 C  CG    . PHE A 1 482 ? 42.59600  25.43000  35.54900  1.000 277.15000 ? 482 PHE A CG    1 
ATOM   3626 C  CD1   . PHE A 1 482 ? 42.03200  26.35600  34.71100  1.000 288.85000 ? 482 PHE A CD1   1 
ATOM   3627 C  CD2   . PHE A 1 482 ? 42.66700  24.11100  35.14600  1.000 277.03000 ? 482 PHE A CD2   1 
ATOM   3628 C  CE1   . PHE A 1 482 ? 41.47500  25.98800  33.52700  1.000 296.72000 ? 482 PHE A CE1   1 
ATOM   3629 C  CE2   . PHE A 1 482 ? 42.10400  23.72600  33.94900  1.000 277.56000 ? 482 PHE A CE2   1 
ATOM   3630 C  CZ    . PHE A 1 482 ? 41.50400  24.66800  33.13100  1.000 284.89000 ? 482 PHE A CZ    1 
ATOM   3631 N  N     . ALA A 1 483 ? 46.19000  27.55400  37.96700  1.000 286.69000 ? 483 ALA A N     1 
ATOM   3632 C  CA    . ALA A 1 483 ? 46.64700  28.32200  39.11700  1.000 287.45000 ? 483 ALA A CA    1 
ATOM   3633 C  C     . ALA A 1 483 ? 46.27800  29.78400  39.00000  1.000 291.42000 ? 483 ALA A C     1 
ATOM   3634 O  O     . ALA A 1 483 ? 45.59800  30.33500  39.87500  1.000 295.27000 ? 483 ALA A O     1 
ATOM   3635 C  CB    . ALA A 1 483 ? 48.15700  28.20100  39.25800  1.000 299.17000 ? 483 ALA A CB    1 
ATOM   3636 N  N     . ASN A 1 484 ? 46.71200  30.42100  37.91500  1.000 295.08000 ? 484 ASN A N     1 
ATOM   3637 C  CA    . ASN A 1 484 ? 46.52600  31.85200  37.78800  1.000 296.42000 ? 484 ASN A CA    1 
ATOM   3638 C  C     . ASN A 1 484 ? 45.05400  32.20700  37.84800  1.000 293.91000 ? 484 ASN A C     1 
ATOM   3639 O  O     . ASN A 1 484 ? 44.65800  33.10500  38.60800  1.000 300.91000 ? 484 ASN A O     1 
ATOM   3640 C  CB    . ASN A 1 484 ? 47.18200  32.33000  36.49300  1.000 306.88000 ? 484 ASN A CB    1 
ATOM   3641 C  CG    . ASN A 1 484 ? 48.66500  31.90200  36.38800  1.000 321.02000 ? 484 ASN A CG    1 
ATOM   3642 O  OD1   . ASN A 1 484 ? 49.30500  31.55900  37.38100  1.000 333.77000 ? 484 ASN A OD1   1 
ATOM   3643 N  ND2   . ASN A 1 484 ? 49.22100  31.94800  35.17600  1.000 318.39000 ? 484 ASN A ND2   1 
ATOM   3644 N  N     . LYS A 1 485 ? 44.21600  31.46700  37.12000  1.000 290.84000 ? 485 LYS A N     1 
ATOM   3645 C  CA    . LYS A 1 485 ? 42.78700  31.67000  37.32000  1.000 289.01000 ? 485 LYS A CA    1 
ATOM   3646 C  C     . LYS A 1 485 ? 42.38900  31.36400  38.75100  1.000 287.11000 ? 485 LYS A C     1 
ATOM   3647 O  O     . LYS A 1 485 ? 41.67800  32.14700  39.39500  1.000 292.16000 ? 485 LYS A O     1 
ATOM   3648 C  CB    . LYS A 1 485 ? 41.97100  30.80700  36.37000  1.000 290.57000 ? 485 LYS A CB    1 
ATOM   3649 C  CG    . LYS A 1 485 ? 40.50000  31.06100  36.53200  1.000 286.38000 ? 485 LYS A CG    1 
ATOM   3650 C  CD    . LYS A 1 485 ? 39.71100  29.97400  35.87500  1.000 294.44000 ? 485 LYS A CD    1 
ATOM   3651 C  CE    . LYS A 1 485 ? 39.03800  30.49100  34.62300  1.000 309.34000 ? 485 LYS A CE    1 
ATOM   3652 N  NZ    . LYS A 1 485 ? 38.20000  29.46800  33.93500  1.000 308.81000 ? 485 LYS A NZ    1 
ATOM   3653 N  N     . ILE A 1 486 ? 42.85500  30.23900  39.27000  1.000 297.53000 ? 486 ILE A N     1 
ATOM   3654 C  CA    . ILE A 1 486 ? 42.57900  29.94000  40.66600  1.000 304.44000 ? 486 ILE A CA    1 
ATOM   3655 C  C     . ILE A 1 486 ? 43.12500  31.04500  41.55900  1.000 307.97000 ? 486 ILE A C     1 
ATOM   3656 O  O     . ILE A 1 486 ? 42.45300  31.48100  42.50200  1.000 313.67000 ? 486 ILE A O     1 
ATOM   3657 C  CB    . ILE A 1 486 ? 43.13300  28.54700  41.03300  1.000 307.61000 ? 486 ILE A CB    1 
ATOM   3658 C  CG1   . ILE A 1 486 ? 42.22700  27.46200  40.41300  1.000 306.66000 ? 486 ILE A CG1   1 
ATOM   3659 C  CG2   . ILE A 1 486 ? 43.21500  28.35600  42.51900  1.000 309.53000 ? 486 ILE A CG2   1 
ATOM   3660 C  CD1   . ILE A 1 486 ? 42.16300  26.15500  41.24300  1.000 306.38000 ? 486 ILE A CD1   1 
ATOM   3661 N  N     . GLY A 1 487 ? 44.31400  31.55800  41.23300  1.000 308.25000 ? 487 GLY A N     1 
ATOM   3662 C  CA    . GLY A 1 487 ? 44.97000  32.49700  42.12200  1.000 313.57000 ? 487 GLY A CA    1 
ATOM   3663 C  C     . GLY A 1 487 ? 44.06200  33.65600  42.49200  1.000 313.34000 ? 487 GLY A C     1 
ATOM   3664 O  O     . GLY A 1 487 ? 44.01100  34.08900  43.65400  1.000 313.52000 ? 487 GLY A O     1 
ATOM   3665 N  N     . GLU A 1 488 ? 43.28600  34.13300  41.51600  1.000 313.71000 ? 488 GLU A N     1 
ATOM   3666 C  CA    . GLU A 1 488 ? 42.31100  35.18400  41.77900  1.000 321.07000 ? 488 GLU A CA    1 
ATOM   3667 C  C     . GLU A 1 488 ? 41.26800  34.73400  42.79800  1.000 313.19000 ? 488 GLU A C     1 
ATOM   3668 O  O     . GLU A 1 488 ? 40.98800  35.44400  43.77500  1.000 315.66000 ? 488 GLU A O     1 
ATOM   3669 C  CB    . GLU A 1 488 ? 41.65200  35.58300  40.45600  1.000 332.99000 ? 488 GLU A CB    1 
ATOM   3670 C  CG    . GLU A 1 488 ? 42.63800  36.15800  39.42400  1.000 335.84000 ? 488 GLU A CG    1 
ATOM   3671 C  CD    . GLU A 1 488 ? 42.65700  37.68800  39.43100  1.000 353.32000 ? 488 GLU A CD    1 
ATOM   3672 O  OE1   . GLU A 1 488 ? 41.56200  38.29600  39.37200  1.000 351.48000 ? 488 GLU A OE1   1 
ATOM   3673 O  OE2   . GLU A 1 488 ? 43.75700  38.28500  39.50100  1.000 358.50000 ? 488 GLU A OE2   1 
ATOM   3674 N  N     . ILE A 1 489 ? 40.73600  33.52400  42.61600  1.000 312.03000 ? 489 ILE A N     1 
ATOM   3675 C  CA    . ILE A 1 489 ? 39.53100  33.11500  43.33200  1.000 311.51000 ? 489 ILE A CA    1 
ATOM   3676 C  C     . ILE A 1 489 ? 39.82800  32.89000  44.80600  1.000 314.54000 ? 489 ILE A C     1 
ATOM   3677 O  O     . ILE A 1 489 ? 38.96000  33.08500  45.67200  1.000 316.46000 ? 489 ILE A O     1 
ATOM   3678 C  CB    . ILE A 1 489 ? 38.93000  31.86800  42.66200  1.000 307.99000 ? 489 ILE A CB    1 
ATOM   3679 C  CG1   . ILE A 1 489 ? 39.00300  32.05300  41.17100  1.000 310.02000 ? 489 ILE A CG1   1 
ATOM   3680 C  CG2   . ILE A 1 489 ? 37.49900  31.63200  43.15000  1.000 311.95000 ? 489 ILE A CG2   1 
ATOM   3681 C  CD1   . ILE A 1 489 ? 38.29400  31.02800  40.38100  1.000 311.87000 ? 489 ILE A CD1   1 
ATOM   3682 N  N     . LEU A 1 490 ? 41.05800  32.48000  45.11000  1.000 322.50000 ? 490 LEU A N     1 
ATOM   3683 C  CA    . LEU A 1 490 ? 41.51300  32.41900  46.49100  1.000 328.51000 ? 490 LEU A CA    1 
ATOM   3684 C  C     . LEU A 1 490 ? 41.50500  33.80300  47.12000  1.000 331.18000 ? 490 LEU A C     1 
ATOM   3685 O  O     . LEU A 1 490 ? 40.93000  34.01000  48.18800  1.000 343.63000 ? 490 LEU A O     1 
ATOM   3686 C  CB    . LEU A 1 490 ? 42.93300  31.83100  46.55300  1.000 327.05000 ? 490 LEU A CB    1 
ATOM   3687 C  CG    . LEU A 1 490 ? 43.28000  30.36500  46.25600  1.000 329.93000 ? 490 LEU A CG    1 
ATOM   3688 C  CD1   . LEU A 1 490 ? 44.80000  30.25900  46.20800  1.000 326.98000 ? 490 LEU A CD1   1 
ATOM   3689 C  CD2   . LEU A 1 490 ? 42.72500  29.41300  47.30800  1.000 317.59000 ? 490 LEU A CD2   1 
ATOM   3690 N  N     . THR A 1 491 ? 42.16900  34.76300  46.48000  1.000 325.81000 ? 491 THR A N     1 
ATOM   3691 C  CA    . THR A 1 491 ? 42.27600  36.08600  47.08500  1.000 333.08000 ? 491 THR A CA    1 
ATOM   3692 C  C     . THR A 1 491 ? 40.94400  36.81700  47.02100  1.000 339.84000 ? 491 THR A C     1 
ATOM   3693 O  O     . THR A 1 491 ? 40.57200  37.52300  47.97400  1.000 348.64000 ? 491 THR A O     1 
ATOM   3694 C  CB    . THR A 1 491 ? 43.38500  36.89700  46.40900  1.000 329.66000 ? 491 THR A CB    1 
ATOM   3695 O  OG1   . THR A 1 491 ? 44.67000  36.36100  46.76800  1.000 325.35000 ? 491 THR A OG1   1 
ATOM   3696 C  CG2   . THR A 1 491 ? 43.32000  38.36100  46.81400  1.000 337.31000 ? 491 THR A CG2   1 
ATOM   3697 N  N     . ALA A 1 492 ? 40.17900  36.58900  45.94400  1.000 333.77000 ? 492 ALA A N     1 
ATOM   3698 C  CA    . ALA A 1 492 ? 38.91400  37.29500  45.77600  1.000 338.56000 ? 492 ALA A CA    1 
ATOM   3699 C  C     . ALA A 1 492 ? 37.99400  37.12200  46.98500  1.000 347.25000 ? 492 ALA A C     1 
ATOM   3700 O  O     . ALA A 1 492 ? 37.36100  38.09000  47.42700  1.000 356.63000 ? 492 ALA A O     1 
ATOM   3701 C  CB    . ALA A 1 492 ? 38.22600  36.82400  44.48900  1.000 327.23000 ? 492 ALA A CB    1 
ATOM   3702 N  N     . SER A 1 493 ? 37.88100  35.89700  47.52100  1.000 345.79000 ? 493 SER A N     1 
ATOM   3703 C  CA    . SER A 1 493 ? 37.11100  35.61900  48.74300  1.000 345.05000 ? 493 SER A CA    1 
ATOM   3704 C  C     . SER A 1 493 ? 38.08300  35.10300  49.79800  1.000 350.02000 ? 493 SER A C     1 
ATOM   3705 O  O     . SER A 1 493 ? 38.66500  34.03000  49.62100  1.000 358.74000 ? 493 SER A O     1 
ATOM   3706 C  CB    . SER A 1 493 ? 36.00800  34.59600  48.47300  1.000 340.49000 ? 493 SER A CB    1 
ATOM   3707 O  OG    . SER A 1 493 ? 34.95300  34.62400  49.42000  1.000 350.10000 ? 493 SER A OG    1 
ATOM   3708 N  N     . THR A 1 494 ? 38.31900  35.88400  50.86200  1.000 348.92000 ? 494 THR A N     1 
ATOM   3709 C  CA    . THR A 1 494 ? 39.28400  35.48200  51.87900  1.000 350.56000 ? 494 THR A CA    1 
ATOM   3710 C  C     . THR A 1 494 ? 38.69700  35.24800  53.24300  1.000 350.07000 ? 494 THR A C     1 
ATOM   3711 O  O     . THR A 1 494 ? 39.36100  34.59700  54.07500  1.000 345.76000 ? 494 THR A O     1 
ATOM   3712 C  CB    . THR A 1 494 ? 40.39200  36.53200  52.05700  1.000 345.30000 ? 494 THR A CB    1 
ATOM   3713 O  OG1   . THR A 1 494 ? 40.34900  37.49300  50.99500  1.000 347.47000 ? 494 THR A OG1   1 
ATOM   3714 C  CG2   . THR A 1 494 ? 41.76600  35.85100  52.12900  1.000 336.05000 ? 494 THR A CG2   1 
ATOM   3715 N  N     . GLU A 1 495 ? 37.51600  35.80000  53.51700  1.000 344.34000 ? 495 GLU A N     1 
ATOM   3716 C  CA    . GLU A 1 495 ? 36.88700  35.52500  54.79300  1.000 349.39000 ? 495 GLU A CA    1 
ATOM   3717 C  C     . GLU A 1 495 ? 36.53900  34.05000  54.91700  1.000 348.22000 ? 495 GLU A C     1 
ATOM   3718 O  O     . GLU A 1 495 ? 36.75100  33.43800  55.97100  1.000 343.29000 ? 495 GLU A O     1 
ATOM   3719 C  CB    . GLU A 1 495 ? 35.64200  36.40200  54.93900  1.000 360.88000 ? 495 GLU A CB    1 
ATOM   3720 C  CG    . GLU A 1 495 ? 34.57100  35.81200  55.83100  1.000 367.24000 ? 495 GLU A CG    1 
ATOM   3721 C  CD    . GLU A 1 495 ? 33.65600  36.86600  56.42800  1.000 367.32000 ? 495 GLU A CD    1 
ATOM   3722 O  OE1   . GLU A 1 495 ? 33.68800  37.03600  57.66800  1.000 359.27000 ? 495 GLU A OE1   1 
ATOM   3723 O  OE2   . GLU A 1 495 ? 32.93200  37.53200  55.65700  1.000 383.63000 ? 495 GLU A OE2   1 
ATOM   3724 N  N     . ILE A 1 496 ? 36.03900  33.45400  53.83300  1.000 350.70000 ? 496 ILE A N     1 
ATOM   3725 C  CA    . ILE A 1 496 ? 35.53600  32.08900  53.90500  1.000 338.82000 ? 496 ILE A CA    1 
ATOM   3726 C  C     . ILE A 1 496 ? 36.61300  31.15100  54.41200  1.000 333.33000 ? 496 ILE A C     1 
ATOM   3727 O  O     . ILE A 1 496 ? 37.80300  31.49000  54.44900  1.000 333.64000 ? 496 ILE A O     1 
ATOM   3728 C  CB    . ILE A 1 496 ? 35.01800  31.62600  52.53400  1.000 336.93000 ? 496 ILE A CB    1 
ATOM   3729 C  CG1   . ILE A 1 496 ? 35.78000  32.32200  51.41600  1.000 341.19000 ? 496 ILE A CG1   1 
ATOM   3730 C  CG2   . ILE A 1 496 ? 33.55600  31.93000  52.39800  1.000 335.21000 ? 496 ILE A CG2   1 
ATOM   3731 C  CD1   . ILE A 1 496 ? 37.22800  31.85400  51.28100  1.000 345.88000 ? 496 ILE A CD1   1 
ATOM   3732 N  N     . LYS A 1 497 ? 36.17900  29.98200  54.85100  1.000 324.51000 ? 497 LYS A N     1 
ATOM   3733 C  CA    . LYS A 1 497 ? 37.04200  28.82100  55.07800  1.000 316.23000 ? 497 LYS A CA    1 
ATOM   3734 C  C     . LYS A 1 497 ? 36.30900  27.67700  54.38900  1.000 321.19000 ? 497 LYS A C     1 
ATOM   3735 O  O     . LYS A 1 497 ? 35.62100  26.87700  55.03600  1.000 313.54000 ? 497 LYS A O     1 
ATOM   3736 C  CB    . LYS A 1 497 ? 37.29400  28.55800  56.56800  1.000 325.68000 ? 497 LYS A CB    1 
ATOM   3737 C  CG    . LYS A 1 497 ? 37.94900  29.72700  57.23200  1.000 336.08000 ? 497 LYS A CG    1 
ATOM   3738 C  CD    . LYS A 1 497 ? 39.38100  29.50000  57.64500  1.000 330.40000 ? 497 LYS A CD    1 
ATOM   3739 C  CE    . LYS A 1 497 ? 39.44600  28.82400  58.99900  1.000 332.72000 ? 497 LYS A CE    1 
ATOM   3740 N  NZ    . LYS A 1 497 ? 39.35200  29.77300  60.14800  1.000 327.63000 ? 497 LYS A NZ    1 
ATOM   3741 N  N     . THR A 1 498 ? 36.44500  27.63500  53.08400  1.000 343.34000 ? 498 THR A N     1 
ATOM   3742 C  CA    . THR A 1 498 ? 35.68200  26.69000  52.32500  1.000 340.12000 ? 498 THR A CA    1 
ATOM   3743 C  C     . THR A 1 498 ? 36.27900  25.30100  52.41800  1.000 336.74000 ? 498 THR A C     1 
ATOM   3744 O  O     . THR A 1 498 ? 37.51800  25.14300  52.51500  1.000 343.15000 ? 498 THR A O     1 
ATOM   3745 C  CB    . THR A 1 498 ? 35.56800  27.11300  50.86800  1.000 337.19000 ? 498 THR A CB    1 
ATOM   3746 O  OG1   . THR A 1 498 ? 36.62900  28.01300  50.50000  1.000 338.73000 ? 498 THR A OG1   1 
ATOM   3747 C  CG2   . THR A 1 498 ? 34.21900  27.72200  50.63000  1.000 325.51000 ? 498 THR A CG2   1 
ATOM   3748 N  N     . PRO A 1 499 ? 35.42600  24.27900  52.41500  1.000 328.19000 ? 499 PRO A N     1 
ATOM   3749 C  CA    . PRO A 1 499 ? 35.91000  22.92500  52.42100  1.000 321.66000 ? 499 PRO A CA    1 
ATOM   3750 C  C     . PRO A 1 499 ? 36.70400  22.64600  51.15100  1.000 318.56000 ? 499 PRO A C     1 
ATOM   3751 O  O     . PRO A 1 499 ? 36.70900  23.45000  50.20400  1.000 313.39000 ? 499 PRO A O     1 
ATOM   3752 C  CB    . PRO A 1 499 ? 34.62700  22.07200  52.47000  1.000 319.25000 ? 499 PRO A CB    1 
ATOM   3753 C  CG    . PRO A 1 499 ? 33.66600  22.91700  51.74200  1.000 315.62000 ? 499 PRO A CG    1 
ATOM   3754 C  CD    . PRO A 1 499 ? 33.98200  24.32500  52.06000  1.000 322.66000 ? 499 PRO A CD    1 
ATOM   3755 N  N     . PRO A 1 500 ? 37.53100  21.60300  51.15100  1.000 313.98000 ? 500 PRO A N     1 
ATOM   3756 C  CA    . PRO A 1 500 ? 38.09100  21.15300  49.86100  1.000 308.05000 ? 500 PRO A CA    1 
ATOM   3757 C  C     . PRO A 1 500 ? 36.99500  20.92700  48.82500  1.000 305.85000 ? 500 PRO A C     1 
ATOM   3758 O  O     . PRO A 1 500 ? 35.96200  20.32300  49.11200  1.000 313.26000 ? 500 PRO A O     1 
ATOM   3759 C  CB    . PRO A 1 500 ? 38.80500  19.85000  50.20600  1.000 312.87000 ? 500 PRO A CB    1 
ATOM   3760 C  CG    . PRO A 1 500 ? 39.11200  19.99400  51.68400  1.000 311.80000 ? 500 PRO A CG    1 
ATOM   3761 C  CD    . PRO A 1 500 ? 38.05400  20.84100  52.30500  1.000 312.98000 ? 500 PRO A CD    1 
ATOM   3762 N  N     . LEU A 1 501 ? 37.20600  21.43600  47.61000  1.000 299.78000 ? 501 LEU A N     1 
ATOM   3763 C  CA    . LEU A 1 501 ? 36.13800  21.40300  46.61600  1.000 300.81000 ? 501 LEU A CA    1 
ATOM   3764 C  C     . LEU A 1 501 ? 36.65200  20.91300  45.26600  1.000 299.65000 ? 501 LEU A C     1 
ATOM   3765 O  O     . LEU A 1 501 ? 37.81300  21.13100  44.89800  1.000 297.16000 ? 501 LEU A O     1 
ATOM   3766 C  CB    . LEU A 1 501 ? 35.46800  22.77400  46.46500  1.000 300.55000 ? 501 LEU A CB    1 
ATOM   3767 C  CG    . LEU A 1 501 ? 34.86200  23.35000  47.73500  1.000 300.13000 ? 501 LEU A CG    1 
ATOM   3768 C  CD1   . LEU A 1 501 ? 35.53300  24.67500  48.04900  1.000 306.92000 ? 501 LEU A CD1   1 
ATOM   3769 C  CD2   . LEU A 1 501 ? 33.35300  23.51400  47.63800  1.000 298.23000 ? 501 LEU A CD2   1 
ATOM   3770 N  N     . ALA A 1 502 ? 35.75700  20.23900  44.53500  1.000 300.21000 ? 502 ALA A N     1 
ATOM   3771 C  CA    . ALA A 1 502 ? 36.04000  19.82700  43.17000  1.000 300.16000 ? 502 ALA A CA    1 
ATOM   3772 C  C     . ALA A 1 502 ? 36.13300  21.05300  42.26500  1.000 301.88000 ? 502 ALA A C     1 
ATOM   3773 O  O     . ALA A 1 502 ? 35.75000  22.17400  42.64700  1.000 299.72000 ? 502 ALA A O     1 
ATOM   3774 C  CB    . ALA A 1 502 ? 34.96600  18.87400  42.64900  1.000 303.44000 ? 502 ALA A CB    1 
ATOM   3775 N  N     . PHE A 1 503 ? 36.66400  20.83400  41.04900  1.000 301.99000 ? 503 PHE A N     1 
ATOM   3776 C  CA    . PHE A 1 503 ? 37.01200  21.96500  40.18400  1.000 302.53000 ? 503 PHE A CA    1 
ATOM   3777 C  C     . PHE A 1 503 ? 35.78300  22.79600  39.80100  1.000 302.33000 ? 503 PHE A C     1 
ATOM   3778 O  O     . PHE A 1 503 ? 35.81200  24.03800  39.91000  1.000 303.35000 ? 503 PHE A O     1 
ATOM   3779 C  CB    . PHE A 1 503 ? 37.75800  21.46400  38.94200  1.000 304.07000 ? 503 PHE A CB    1 
ATOM   3780 C  CG    . PHE A 1 503 ? 39.26700  21.77400  38.94900  1.000 302.36000 ? 503 PHE A CG    1 
ATOM   3781 C  CD1   . PHE A 1 503 ? 39.99300  21.90000  37.76000  1.000 297.21000 ? 503 PHE A CD1   1 
ATOM   3782 C  CD2   . PHE A 1 503 ? 39.94700  21.94000  40.13700  1.000 301.78000 ? 503 PHE A CD2   1 
ATOM   3783 C  CE1   . PHE A 1 503 ? 41.35400  22.20200  37.77000  1.000 291.76000 ? 503 PHE A CE1   1 
ATOM   3784 C  CE2   . PHE A 1 503 ? 41.30800  22.23600  40.15700  1.000 300.76000 ? 503 PHE A CE2   1 
ATOM   3785 C  CZ    . PHE A 1 503 ? 42.01000  22.38300  38.97500  1.000 296.24000 ? 503 PHE A CZ    1 
ATOM   3786 N  N     . LYS A 1 504 ? 34.67400  22.12500  39.42700  1.000 297.11000 ? 504 LYS A N     1 
ATOM   3787 C  CA    . LYS A 1 504 ? 33.52100  22.82400  38.86300  1.000 295.60000 ? 504 LYS A CA    1 
ATOM   3788 C  C     . LYS A 1 504 ? 33.13000  24.03900  39.68100  1.000 291.06000 ? 504 LYS A C     1 
ATOM   3789 O  O     . LYS A 1 504 ? 32.66400  25.05100  39.13200  1.000 290.07000 ? 504 LYS A O     1 
ATOM   3790 C  CB    . LYS A 1 504 ? 32.33900  21.85600  38.73200  1.000 293.38000 ? 504 LYS A CB    1 
ATOM   3791 C  CG    . LYS A 1 504 ? 32.25300  20.73800  39.75800  1.000 291.03000 ? 504 LYS A CG    1 
ATOM   3792 C  CD    . LYS A 1 504 ? 31.15500  19.73700  39.36100  1.000 288.22000 ? 504 LYS A CD    1 
ATOM   3793 C  CE    . LYS A 1 504 ? 30.35100  19.26400  40.57000  1.000 290.74000 ? 504 LYS A CE    1 
ATOM   3794 N  NZ    . LYS A 1 504 ? 28.92400  18.96100  40.22500  1.000 281.89000 ? 504 LYS A NZ    1 
ATOM   3795 N  N     . TYR A 1 505 ? 33.32400  23.96600  40.98600  1.000 288.97000 ? 505 TYR A N     1 
ATOM   3796 C  CA    . TYR A 1 505 ? 33.05900  25.13600  41.79200  1.000 290.89000 ? 505 TYR A CA    1 
ATOM   3797 C  C     . TYR A 1 505 ? 34.09900  26.22500  41.53400  1.000 293.60000 ? 505 TYR A C     1 
ATOM   3798 O  O     . TYR A 1 505 ? 33.73700  27.38700  41.33600  1.000 298.43000 ? 505 TYR A O     1 
ATOM   3799 C  CB    . TYR A 1 505 ? 32.96200  24.67800  43.24100  1.000 291.41000 ? 505 TYR A CB    1 
ATOM   3800 C  CG    . TYR A 1 505 ? 31.91700  23.58400  43.30400  1.000 296.89000 ? 505 TYR A CG    1 
ATOM   3801 C  CD1   . TYR A 1 505 ? 30.72600  23.72400  42.59400  1.000 299.08000 ? 505 TYR A CD1   1 
ATOM   3802 C  CD2   . TYR A 1 505 ? 32.13500  22.39300  44.00800  1.000 297.98000 ? 505 TYR A CD2   1 
ATOM   3803 C  CE1   . TYR A 1 505 ? 29.76300  22.74100  42.60800  1.000 302.77000 ? 505 TYR A CE1   1 
ATOM   3804 C  CE2   . TYR A 1 505 ? 31.16600  21.39400  44.02900  1.000 298.62000 ? 505 TYR A CE2   1 
ATOM   3805 C  CZ    . TYR A 1 505 ? 29.98600  21.57600  43.32700  1.000 305.65000 ? 505 TYR A CZ    1 
ATOM   3806 O  OH    . TYR A 1 505 ? 29.01300  20.60500  43.32900  1.000 312.92000 ? 505 TYR A OH    1 
ATOM   3807 N  N     . TYR A 1 506 ? 35.37100  25.84500  41.38800  1.000 298.75000 ? 506 TYR A N     1 
ATOM   3808 C  CA    . TYR A 1 506 ? 36.50800  26.74900  41.20200  1.000 302.61000 ? 506 TYR A CA    1 
ATOM   3809 C  C     . TYR A 1 506 ? 36.74200  27.18200  39.75500  1.000 311.22000 ? 506 TYR A C     1 
ATOM   3810 O  O     . TYR A 1 506 ? 37.59300  28.04600  39.51500  1.000 318.89000 ? 506 TYR A O     1 
ATOM   3811 C  CB    . TYR A 1 506 ? 37.80000  26.08300  41.71500  1.000 303.20000 ? 506 TYR A CB    1 
ATOM   3812 C  CG    . TYR A 1 506 ? 37.99300  26.14500  43.20100  1.000 304.59000 ? 506 TYR A CG    1 
ATOM   3813 C  CD1   . TYR A 1 506 ? 39.07600  26.82300  43.75100  1.000 304.27000 ? 506 TYR A CD1   1 
ATOM   3814 C  CD2   . TYR A 1 506 ? 37.09700  25.53700  44.05600  1.000 309.28000 ? 506 TYR A CD2   1 
ATOM   3815 C  CE1   . TYR A 1 506 ? 39.25500  26.89700  45.11100  1.000 310.94000 ? 506 TYR A CE1   1 
ATOM   3816 C  CE2   . TYR A 1 506 ? 37.27200  25.60000  45.42100  1.000 313.13000 ? 506 TYR A CE2   1 
ATOM   3817 C  CZ    . TYR A 1 506 ? 38.34100  26.27300  45.95300  1.000 312.89000 ? 506 TYR A CZ    1 
ATOM   3818 O  OH    . TYR A 1 506 ? 38.46500  26.31000  47.33300  1.000 308.26000 ? 506 TYR A OH    1 
ATOM   3819 N  N     . ILE A 1 507 ? 36.03000  26.60900  38.79300  1.000 309.55000 ? 507 ILE A N     1 
ATOM   3820 C  CA    . ILE A 1 507 ? 36.29900  26.82100  37.37000  1.000 314.51000 ? 507 ILE A CA    1 
ATOM   3821 C  C     . ILE A 1 507 ? 36.06700  28.28200  36.99600  1.000 321.06000 ? 507 ILE A C     1 
ATOM   3822 O  O     . ILE A 1 507 ? 35.78500  29.09800  37.87800  1.000 321.49000 ? 507 ILE A O     1 
ATOM   3823 C  CB    . ILE A 1 507 ? 35.46900  25.82000  36.55600  1.000 311.50000 ? 507 ILE A CB    1 
ATOM   3824 C  CG1   . ILE A 1 507 ? 36.03500  24.43100  36.77400  1.000 306.92000 ? 507 ILE A CG1   1 
ATOM   3825 C  CG2   . ILE A 1 507 ? 35.44300  26.10000  35.04000  1.000 310.47000 ? 507 ILE A CG2   1 
ATOM   3826 C  CD1   . ILE A 1 507 ? 35.24200  23.32600  36.08300  1.000 301.81000 ? 507 ILE A CD1   1 
ATOM   3827 O  OXT   . ILE A 1 507 ? 36.20900  28.64500  35.83500  1.000 319.11000 ? 507 ILE A OXT   1 
ATOM   3828 N  N     . MET B 2 1   ? 23.51200  -14.77300 1.82300   1.000 342.47000 ? 1   MET B N     1 
ATOM   3829 C  CA    . MET B 2 1   ? 22.93000  -13.99300 2.91100   1.000 348.17000 ? 1   MET B CA    1 
ATOM   3830 C  C     . MET B 2 1   ? 23.37900  -12.53300 2.83200   1.000 348.40000 ? 1   MET B C     1 
ATOM   3831 O  O     . MET B 2 1   ? 24.40200  -12.24100 2.21500   1.000 342.36000 ? 1   MET B O     1 
ATOM   3832 C  CB    . MET B 2 1   ? 23.29100  -14.60500 4.26500   1.000 346.87000 ? 1   MET B CB    1 
ATOM   3833 C  CG    . MET B 2 1   ? 22.10600  -15.29700 4.90300   1.000 344.27000 ? 1   MET B CG    1 
ATOM   3834 S  SD    . MET B 2 1   ? 22.25400  -17.09300 4.96900   1.000 379.97000 ? 1   MET B SD    1 
ATOM   3835 C  CE    . MET B 2 1   ? 21.10900  -17.46900 6.29800   1.000 333.44000 ? 1   MET B CE    1 
ATOM   3836 N  N     . ARG B 2 2   ? 22.60400  -11.62100 3.42500   1.000 356.51000 ? 2   ARG B N     1 
ATOM   3837 C  CA    . ARG B 2 2   ? 22.84300  -10.18500 3.30500   1.000 351.89000 ? 2   ARG B CA    1 
ATOM   3838 C  C     . ARG B 2 2   ? 22.67200  -9.49600  4.65500   1.000 357.38000 ? 2   ARG B C     1 
ATOM   3839 O  O     . ARG B 2 2   ? 21.61600  -9.61900  5.28200   1.000 354.63000 ? 2   ARG B O     1 
ATOM   3840 C  CB    . ARG B 2 2   ? 21.91000  -9.57400  2.25700   1.000 338.86000 ? 2   ARG B CB    1 
ATOM   3841 C  CG    . ARG B 2 2   ? 20.40600  -9.77800  2.47600   1.000 348.00000 ? 2   ARG B CG    1 
ATOM   3842 C  CD    . ARG B 2 2   ? 19.92900  -11.11300 1.95300   1.000 354.29000 ? 2   ARG B CD    1 
ATOM   3843 N  NE    . ARG B 2 2   ? 18.81700  -11.69800 2.69700   1.000 358.39000 ? 2   ARG B NE    1 
ATOM   3844 C  CZ    . ARG B 2 2   ? 18.96000  -12.54700 3.72200   1.000 355.73000 ? 2   ARG B CZ    1 
ATOM   3845 N  NH1   . ARG B 2 2   ? 20.16400  -12.90400 4.14000   1.000 357.93000 ? 2   ARG B NH1   1 
ATOM   3846 N  NH2   . ARG B 2 2   ? 17.89700  -13.05800 4.34100   1.000 356.23000 ? 2   ARG B NH2   1 
ATOM   3847 N  N     . ASN B 2 3   ? 23.71800  -8.76100  5.09100   1.000 368.22000 ? 3   ASN B N     1 
ATOM   3848 C  CA    . ASN B 2 3   ? 23.81700  -8.17600  6.43200   1.000 359.58000 ? 3   ASN B CA    1 
ATOM   3849 C  C     . ASN B 2 3   ? 24.22800  -6.69700  6.49100   1.000 358.59000 ? 3   ASN B C     1 
ATOM   3850 O  O     . ASN B 2 3   ? 23.78800  -5.99000  7.41900   1.000 344.82000 ? 3   ASN B O     1 
ATOM   3851 C  CB    . ASN B 2 3   ? 24.81800  -8.98700  7.29700   1.000 355.28000 ? 3   ASN B CB    1 
ATOM   3852 C  CG    . ASN B 2 3   ? 26.14100  -9.33700  6.55100   1.000 355.87000 ? 3   ASN B CG    1 
ATOM   3853 O  OD1   . ASN B 2 3   ? 26.17600  -9.47300  5.31300   1.000 356.30000 ? 3   ASN B OD1   1 
ATOM   3854 N  ND2   . ASN B 2 3   ? 27.21400  -9.51500  7.31500   1.000 355.00000 ? 3   ASN B ND2   1 
ATOM   3855 N  N     . LYS B 2 4   ? 25.04100  -6.21700  5.54000   1.000 359.83000 ? 4   LYS B N     1 
ATOM   3856 C  CA    . LYS B 2 4   ? 25.70700  -4.92400  5.62000   1.000 344.71000 ? 4   LYS B CA    1 
ATOM   3857 C  C     . LYS B 2 4   ? 24.72600  -3.75800  5.62500   1.000 340.52000 ? 4   LYS B C     1 
ATOM   3858 O  O     . LYS B 2 4   ? 23.50400  -3.91400  5.54800   1.000 345.20000 ? 4   LYS B O     1 
ATOM   3859 C  CB    . LYS B 2 4   ? 26.67900  -4.75000  4.44600   1.000 335.50000 ? 4   LYS B CB    1 
ATOM   3860 C  CG    . LYS B 2 4   ? 28.01100  -5.43300  4.70400   1.000 318.98000 ? 4   LYS B CG    1 
ATOM   3861 C  CD    . LYS B 2 4   ? 28.82000  -5.66300  3.46400   1.000 314.98000 ? 4   LYS B CD    1 
ATOM   3862 C  CE    . LYS B 2 4   ? 29.87700  -6.69500  3.79300   1.000 314.49000 ? 4   LYS B CE    1 
ATOM   3863 N  NZ    . LYS B 2 4   ? 30.62800  -7.18100  2.62400   1.000 319.79000 ? 4   LYS B NZ    1 
ATOM   3864 N  N     . ILE B 2 5   ? 25.29400  -2.57100  5.75400   1.000 334.91000 ? 5   ILE B N     1 
ATOM   3865 C  CA    . ILE B 2 5   ? 24.56000  -1.32200  5.62700   1.000 326.64000 ? 5   ILE B CA    1 
ATOM   3866 C  C     . ILE B 2 5   ? 25.45600  -0.45100  4.75600   1.000 320.18000 ? 5   ILE B C     1 
ATOM   3867 O  O     . ILE B 2 5   ? 26.33700  0.27400   5.23300   1.000 322.58000 ? 5   ILE B O     1 
ATOM   3868 C  CB    . ILE B 2 5   ? 24.21200  -0.69000  6.98100   1.000 312.60000 ? 5   ILE B CB    1 
ATOM   3869 C  CG1   . ILE B 2 5   ? 23.08000  -1.50400  7.60400   1.000 302.41000 ? 5   ILE B CG1   1 
ATOM   3870 C  CG2   . ILE B 2 5   ? 23.79100  0.74400   6.81000   1.000 303.97000 ? 5   ILE B CG2   1 
ATOM   3871 C  CD1   . ILE B 2 5   ? 22.31800  -0.83900  8.69300   1.000 299.63000 ? 5   ILE B CD1   1 
ATOM   3872 N  N     . PHE B 2 6   ? 25.30700  -0.60700  3.44200   1.000 310.49000 ? 6   PHE B N     1 
ATOM   3873 C  CA    . PHE B 2 6   ? 26.12300  0.17500   2.54300   1.000 307.11000 ? 6   PHE B CA    1 
ATOM   3874 C  C     . PHE B 2 6   ? 25.73700  1.63500   2.64300   1.000 318.36000 ? 6   PHE B C     1 
ATOM   3875 O  O     . PHE B 2 6   ? 24.55300  1.98000   2.58300   1.000 317.85000 ? 6   PHE B O     1 
ATOM   3876 C  CB    . PHE B 2 6   ? 25.97300  -0.28100  1.10900   1.000 310.31000 ? 6   PHE B CB    1 
ATOM   3877 C  CG    . PHE B 2 6   ? 26.65200  0.64500   0.16600   1.000 311.68000 ? 6   PHE B CG    1 
ATOM   3878 C  CD1   . PHE B 2 6   ? 25.94900  1.61700   -0.52300  1.000 314.06000 ? 6   PHE B CD1   1 
ATOM   3879 C  CD2   . PHE B 2 6   ? 28.02500  0.61800   0.04800   1.000 317.69000 ? 6   PHE B CD2   1 
ATOM   3880 C  CE1   . PHE B 2 6   ? 26.61300  2.51400   -1.36200  1.000 316.12000 ? 6   PHE B CE1   1 
ATOM   3881 C  CE2   . PHE B 2 6   ? 28.68900  1.50100   -0.78600  1.000 319.78000 ? 6   PHE B CE2   1 
ATOM   3882 C  CZ    . PHE B 2 6   ? 27.98500  2.45300   -1.49800  1.000 318.97000 ? 6   PHE B CZ    1 
ATOM   3883 N  N     . ILE B 2 7   ? 26.73900  2.49400   2.77900   1.000 328.35000 ? 7   ILE B N     1 
ATOM   3884 C  CA    . ILE B 2 7   ? 26.53000  3.93700   2.83500   1.000 331.17000 ? 7   ILE B CA    1 
ATOM   3885 C  C     . ILE B 2 7   ? 27.00100  4.55400   1.50700   1.000 328.92000 ? 7   ILE B C     1 
ATOM   3886 O  O     . ILE B 2 7   ? 28.14200  4.32800   1.07700   1.000 327.24000 ? 7   ILE B O     1 
ATOM   3887 C  CB    . ILE B 2 7   ? 27.23900  4.55000   4.05900   1.000 325.13000 ? 7   ILE B CB    1 
ATOM   3888 C  CG1   . ILE B 2 7   ? 26.52700  4.12500   5.35700   1.000 312.59000 ? 7   ILE B CG1   1 
ATOM   3889 C  CG2   . ILE B 2 7   ? 27.16200  6.00800   3.97800   1.000 317.98000 ? 7   ILE B CG2   1 
ATOM   3890 C  CD1   . ILE B 2 7   ? 26.79300  4.98800   6.57200   1.000 301.80000 ? 7   ILE B CD1   1 
ATOM   3891 N  N     . SER B 2 8   ? 26.12100  5.31100   0.84400   1.000 319.89000 ? 8   SER B N     1 
ATOM   3892 C  CA    . SER B 2 8   ? 26.47100  6.02000   -0.38000  1.000 311.48000 ? 8   SER B CA    1 
ATOM   3893 C  C     . SER B 2 8   ? 26.64900  7.50400   -0.08500  1.000 314.85000 ? 8   SER B C     1 
ATOM   3894 O  O     . SER B 2 8   ? 25.80500  8.09800   0.59300   1.000 317.21000 ? 8   SER B O     1 
ATOM   3895 C  CB    . SER B 2 8   ? 25.39400  5.82600   -1.44600  1.000 309.24000 ? 8   SER B CB    1 
ATOM   3896 O  OG    . SER B 2 8   ? 25.77800  6.47000   -2.66100  1.000 316.52000 ? 8   SER B OG    1 
ATOM   3897 N  N     . HIS B 2 9   ? 27.73800  8.10300   -0.58600  1.000 316.18000 ? 9   HIS B N     1 
ATOM   3898 C  CA    . HIS B 2 9   ? 28.10200  9.42500   -0.08800  1.000 317.34000 ? 9   HIS B CA    1 
ATOM   3899 C  C     . HIS B 2 9   ? 28.98800  10.21500  -1.03100  1.000 312.68000 ? 9   HIS B C     1 
ATOM   3900 O  O     . HIS B 2 9   ? 29.78000  9.66500   -1.80500  1.000 308.25000 ? 9   HIS B O     1 
ATOM   3901 C  CB    . HIS B 2 9   ? 28.83700  9.32100   1.23900   1.000 324.89000 ? 9   HIS B CB    1 
ATOM   3902 C  CG    . HIS B 2 9   ? 30.11600  8.55300   1.15300   1.000 329.72000 ? 9   HIS B CG    1 
ATOM   3903 N  ND1   . HIS B 2 9   ? 31.30000  9.11700   0.73000   1.000 328.13000 ? 9   HIS B ND1   1 
ATOM   3904 C  CD2   . HIS B 2 9   ? 30.38400  7.25100   1.40500   1.000 331.30000 ? 9   HIS B CD2   1 
ATOM   3905 C  CE1   . HIS B 2 9   ? 32.24600  8.19400   0.73700   1.000 330.26000 ? 9   HIS B CE1   1 
ATOM   3906 N  NE2   . HIS B 2 9   ? 31.71600  7.05400   1.14100   1.000 332.80000 ? 9   HIS B NE2   1 
ATOM   3907 N  N     . ALA B 2 10  ? 28.86500  11.53200  -0.87300  1.000 309.65000 ? 10  ALA B N     1 
ATOM   3908 C  CA    . ALA B 2 10  ? 29.70200  12.54500  -1.49100  1.000 311.45000 ? 10  ALA B CA    1 
ATOM   3909 C  C     . ALA B 2 10  ? 30.92300  12.84300  -0.63400  1.000 313.93000 ? 10  ALA B C     1 
ATOM   3910 O  O     . ALA B 2 10  ? 30.81900  13.11900  0.57200   1.000 314.15000 ? 10  ALA B O     1 
ATOM   3911 C  CB    . ALA B 2 10  ? 28.90500  13.84000  -1.68400  1.000 312.78000 ? 10  ALA B CB    1 
ATOM   3912 N  N     . THR B 2 11  ? 32.07900  12.79000  -1.27800  1.000 313.61000 ? 11  THR B N     1 
ATOM   3913 C  CA    . THR B 2 11  ? 33.33000  13.15700  -0.65600  1.000 314.99000 ? 11  THR B CA    1 
ATOM   3914 C  C     . THR B 2 11  ? 33.92600  14.33800  -1.39800  1.000 317.74000 ? 11  THR B C     1 
ATOM   3915 O  O     . THR B 2 11  ? 33.96300  14.33000  -2.63900  1.000 325.30000 ? 11  THR B O     1 
ATOM   3916 C  CB    . THR B 2 11  ? 34.32400  12.01900  -0.69000  1.000 318.52000 ? 11  THR B CB    1 
ATOM   3917 O  OG1   . THR B 2 11  ? 34.50700  11.59900  -2.06100  1.000 326.82000 ? 11  THR B OG1   1 
ATOM   3918 C  CG2   . THR B 2 11  ? 33.80700  10.88000  0.10900   1.000 315.95000 ? 11  THR B CG2   1 
ATOM   3919 N  N     . PRO B 2 12  ? 34.42500  15.34400  -0.67100  1.000 304.96000 ? 12  PRO B N     1 
ATOM   3920 C  CA    . PRO B 2 12  ? 34.52100  15.38800  0.79100   1.000 309.37000 ? 12  PRO B CA    1 
ATOM   3921 C  C     . PRO B 2 12  ? 33.40700  16.17300  1.49700   1.000 314.97000 ? 12  PRO B C     1 
ATOM   3922 O  O     . PRO B 2 12  ? 33.50100  16.43800  2.69000   1.000 318.35000 ? 12  PRO B O     1 
ATOM   3923 C  CB    . PRO B 2 12  ? 35.86800  16.10700  1.01900   1.000 310.80000 ? 12  PRO B CB    1 
ATOM   3924 C  CG    . PRO B 2 12  ? 36.26200  16.68700  -0.32500  1.000 307.14000 ? 12  PRO B CG    1 
ATOM   3925 C  CD    . PRO B 2 12  ? 35.11800  16.47600  -1.28200  1.000 308.95000 ? 12  PRO B CD    1 
ATOM   3926 N  N     . GLU B 2 13  ? 32.34100  16.52000  0.76600   1.000 316.37000 ? 13  GLU B N     1 
ATOM   3927 C  CA    . GLU B 2 13  ? 31.30900  17.40300  1.31600   1.000 319.09000 ? 13  GLU B CA    1 
ATOM   3928 C  C     . GLU B 2 13  ? 30.62400  16.80300  2.53500   1.000 319.09000 ? 13  GLU B C     1 
ATOM   3929 O  O     . GLU B 2 13  ? 30.34300  17.50900  3.50300   1.000 316.46000 ? 13  GLU B O     1 
ATOM   3930 C  CB    . GLU B 2 13  ? 30.27600  17.70600  0.25200   1.000 311.42000 ? 13  GLU B CB    1 
ATOM   3931 C  CG    . GLU B 2 13  ? 30.67000  17.15700  -1.09100  1.000 308.02000 ? 13  GLU B CG    1 
ATOM   3932 C  CD    . GLU B 2 13  ? 31.37900  18.18400  -1.93100  1.000 314.12000 ? 13  GLU B CD    1 
ATOM   3933 O  OE1   . GLU B 2 13  ? 31.33900  19.37800  -1.57500  1.000 327.32000 ? 13  GLU B OE1   1 
ATOM   3934 O  OE2   . GLU B 2 13  ? 31.98100  17.79900  -2.94900  1.000 317.69000 ? 13  GLU B OE2   1 
ATOM   3935 N  N     . ASP B 2 14  ? 30.33200  15.51100  2.50500   1.000 321.96000 ? 14  ASP B N     1 
ATOM   3936 C  CA    . ASP B 2 14  ? 29.58400  14.85100  3.56200   1.000 316.81000 ? 14  ASP B CA    1 
ATOM   3937 C  C     . ASP B 2 14  ? 30.47800  13.95400  4.39600   1.000 313.39000 ? 14  ASP B C     1 
ATOM   3938 O  O     . ASP B 2 14  ? 29.98800  13.20400  5.25200   1.000 307.54000 ? 14  ASP B O     1 
ATOM   3939 C  CB    . ASP B 2 14  ? 28.42400  14.09200  2.91800   1.000 311.94000 ? 14  ASP B CB    1 
ATOM   3940 C  CG    . ASP B 2 14  ? 27.67000  14.98100  1.91400   1.000 312.65000 ? 14  ASP B CG    1 
ATOM   3941 O  OD1   . ASP B 2 14  ? 27.38300  16.14200  2.25800   1.000 319.63000 ? 14  ASP B OD1   1 
ATOM   3942 O  OD2   . ASP B 2 14  ? 27.40700  14.55600  0.77700   1.000 313.94000 ? 14  ASP B OD2   1 
ATOM   3943 N  N     . ASP B 2 15  ? 31.78900  14.03800  4.16200   1.000 317.80000 ? 15  ASP B N     1 
ATOM   3944 C  CA    . ASP B 2 15  ? 32.72800  13.19900  4.88700   1.000 315.11000 ? 15  ASP B CA    1 
ATOM   3945 C  C     . ASP B 2 15  ? 32.54600  13.32700  6.37900   1.000 312.37000 ? 15  ASP B C     1 
ATOM   3946 O  O     . ASP B 2 15  ? 32.55900  12.31800  7.09900   1.000 310.90000 ? 15  ASP B O     1 
ATOM   3947 C  CB    . ASP B 2 15  ? 34.14900  13.58100  4.51900   1.000 314.90000 ? 15  ASP B CB    1 
ATOM   3948 C  CG    . ASP B 2 15  ? 34.73100  12.71700  3.39800   1.000 314.70000 ? 15  ASP B CG    1 
ATOM   3949 O  OD1   . ASP B 2 15  ? 34.02000  11.85100  2.85400   1.000 317.07000 ? 15  ASP B OD1   1 
ATOM   3950 O  OD2   . ASP B 2 15  ? 35.93500  12.94200  3.13000   1.000 320.07000 ? 15  ASP B OD2   1 
ATOM   3951 N  N     . ASP B 2 16  ? 32.38700  14.55800  6.86100   1.000 307.75000 ? 16  ASP B N     1 
ATOM   3952 C  CA    . ASP B 2 16  ? 32.18400  14.73000  8.28200   1.000 311.18000 ? 16  ASP B CA    1 
ATOM   3953 C  C     . ASP B 2 16  ? 30.99500  13.89900  8.74000   1.000 310.22000 ? 16  ASP B C     1 
ATOM   3954 O  O     . ASP B 2 16  ? 31.08400  13.17400  9.73800   1.000 312.38000 ? 16  ASP B O     1 
ATOM   3955 C  CB    . ASP B 2 16  ? 32.05300  16.22700  8.57600   1.000 310.33000 ? 16  ASP B CB    1 
ATOM   3956 C  CG    . ASP B 2 16  ? 33.33900  16.96700  8.22500   1.000 309.42000 ? 16  ASP B CG    1 
ATOM   3957 O  OD1   . ASP B 2 16  ? 34.34500  16.71500  8.92400   1.000 321.83000 ? 16  ASP B OD1   1 
ATOM   3958 O  OD2   . ASP B 2 16  ? 33.40000  17.70100  7.19900   1.000 299.88000 ? 16  ASP B OD2   1 
ATOM   3959 N  N     . PHE B 2 17  ? 29.91800  13.87700  7.95900   1.000 310.68000 ? 17  PHE B N     1 
ATOM   3960 C  CA    . PHE B 2 17  ? 28.76100  13.17800  8.48500   1.000 303.21000 ? 17  PHE B CA    1 
ATOM   3961 C  C     . PHE B 2 17  ? 28.82800  11.65600  8.28800   1.000 297.77000 ? 17  PHE B C     1 
ATOM   3962 O  O     . PHE B 2 17  ? 28.35200  10.89700  9.15100   1.000 295.62000 ? 17  PHE B O     1 
ATOM   3963 C  CB    . PHE B 2 17  ? 27.47100  13.68400  7.89200   1.000 296.11000 ? 17  PHE B CB    1 
ATOM   3964 C  CG    . PHE B 2 17  ? 26.41900  12.73100  8.17200   1.000 292.91000 ? 17  PHE B CG    1 
ATOM   3965 C  CD1   . PHE B 2 17  ? 26.11400  11.76500  7.26300   1.000 295.99000 ? 17  PHE B CD1   1 
ATOM   3966 C  CD2   . PHE B 2 17  ? 25.93000  12.64000  9.43700   1.000 291.84000 ? 17  PHE B CD2   1 
ATOM   3967 C  CE1   . PHE B 2 17  ? 25.25500  10.78200  7.55100   1.000 300.56000 ? 17  PHE B CE1   1 
ATOM   3968 C  CE2   . PHE B 2 17  ? 25.04800  11.67900  9.77900   1.000 293.72000 ? 17  PHE B CE2   1 
ATOM   3969 C  CZ    . PHE B 2 17  ? 24.70200  10.75000  8.82300   1.000 301.10000 ? 17  PHE B CZ    1 
ATOM   3970 N  N     . THR B 2 18  ? 29.26200  11.20700  7.10500   1.000 296.00000 ? 18  THR B N     1 
ATOM   3971 C  CA    . THR B 2 18  ? 29.34800  9.78000   6.79600   1.000 294.16000 ? 18  THR B CA    1 
ATOM   3972 C  C     . THR B 2 18  ? 30.31900  9.08500   7.72700   1.000 295.62000 ? 18  THR B C     1 
ATOM   3973 O  O     . THR B 2 18  ? 30.04300  7.98100   8.22500   1.000 296.47000 ? 18  THR B O     1 
ATOM   3974 C  CB    . THR B 2 18  ? 29.83400  9.60100   5.35000   1.000 295.18000 ? 18  THR B CB    1 
ATOM   3975 O  OG1   . THR B 2 18  ? 29.88700  10.88400  4.72200   1.000 300.97000 ? 18  THR B OG1   1 
ATOM   3976 C  CG2   . THR B 2 18  ? 28.96000  8.66900   4.56400   1.000 297.70000 ? 18  THR B CG2   1 
ATOM   3977 N  N     . ARG B 2 19  ? 31.49100  9.69600   7.93600   1.000 298.61000 ? 19  ARG B N     1 
ATOM   3978 C  CA    . ARG B 2 19  ? 32.42300  9.13700   8.90800   1.000 300.19000 ? 19  ARG B CA    1 
ATOM   3979 C  C     . ARG B 2 19  ? 31.75800  9.00900   10.27100  1.000 302.66000 ? 19  ARG B C     1 
ATOM   3980 O  O     . ARG B 2 19  ? 31.91200  7.98100   10.94600  1.000 304.48000 ? 19  ARG B O     1 
ATOM   3981 C  CB    . ARG B 2 19  ? 33.72800  9.97100   8.94500   1.000 298.83000 ? 19  ARG B CB    1 
ATOM   3982 C  CG    . ARG B 2 19  ? 34.25900  10.48600  10.31000  1.000 292.90000 ? 19  ARG B CG    1 
ATOM   3983 C  CD    . ARG B 2 19  ? 35.60400  11.27000  10.17200  1.000 294.89000 ? 19  ARG B CD    1 
ATOM   3984 N  NE    . ARG B 2 19  ? 36.39200  10.90300  8.98700   1.000 304.51000 ? 19  ARG B NE    1 
ATOM   3985 C  CZ    . ARG B 2 19  ? 36.74000  11.75500  8.02000   1.000 317.55000 ? 19  ARG B CZ    1 
ATOM   3986 N  NH1   . ARG B 2 19  ? 36.37700  13.02500  8.10400   1.000 321.41000 ? 19  ARG B NH1   1 
ATOM   3987 N  NH2   . ARG B 2 19  ? 37.45500  11.34600  6.97200   1.000 324.48000 ? 19  ARG B NH2   1 
ATOM   3988 N  N     . TRP B 2 20  ? 30.91200  9.97700   10.63200  1.000 302.43000 ? 20  TRP B N     1 
ATOM   3989 C  CA    . TRP B 2 20  ? 30.21500  9.89300   11.91300  1.000 305.34000 ? 20  TRP B CA    1 
ATOM   3990 C  C     . TRP B 2 20  ? 29.12600  8.84700   11.88100  1.000 298.24000 ? 20  TRP B C     1 
ATOM   3991 O  O     . TRP B 2 20  ? 28.96900  8.07300   12.83200  1.000 297.09000 ? 20  TRP B O     1 
ATOM   3992 C  CB    . TRP B 2 20  ? 29.59600  11.23600  12.29200  1.000 311.68000 ? 20  TRP B CB    1 
ATOM   3993 C  CG    . TRP B 2 20  ? 28.92100  11.25600  13.67200  1.000 310.91000 ? 20  TRP B CG    1 
ATOM   3994 C  CD1   . TRP B 2 20  ? 29.51300  11.54100  14.88500  1.000 314.51000 ? 20  TRP B CD1   1 
ATOM   3995 C  CD2   . TRP B 2 20  ? 27.54500  10.99000  13.95900  1.000 301.54000 ? 20  TRP B CD2   1 
ATOM   3996 N  NE1   . TRP B 2 20  ? 28.58900  11.46000  15.89900  1.000 308.66000 ? 20  TRP B NE1   1 
ATOM   3997 C  CE2   . TRP B 2 20  ? 27.37500  11.12600  15.36000  1.000 301.66000 ? 20  TRP B CE2   1 
ATOM   3998 C  CE3   . TRP B 2 20  ? 26.43800  10.65100  13.16900  1.000 292.15000 ? 20  TRP B CE3   1 
ATOM   3999 C  CZ2   . TRP B 2 20  ? 26.15300  10.93100  15.98100  1.000 296.28000 ? 20  TRP B CZ2   1 
ATOM   4000 C  CZ3   . TRP B 2 20  ? 25.22400  10.46000  13.78600  1.000 290.84000 ? 20  TRP B CZ3   1 
ATOM   4001 C  CH2   . TRP B 2 20  ? 25.08700  10.60500  15.18300  1.000 296.33000 ? 20  TRP B CH2   1 
ATOM   4002 N  N     . LEU B 2 21  ? 28.34400  8.83100   10.81400  1.000 294.34000 ? 21  LEU B N     1 
ATOM   4003 C  CA    . LEU B 2 21  ? 27.31700  7.81400   10.71600  1.000 297.66000 ? 21  LEU B CA    1 
ATOM   4004 C  C     . LEU B 2 21  ? 27.91300  6.41400   10.74300  1.000 298.44000 ? 21  LEU B C     1 
ATOM   4005 O  O     . LEU B 2 21  ? 27.63700  5.63800   11.66600  1.000 298.35000 ? 21  LEU B O     1 
ATOM   4006 C  CB    . LEU B 2 21  ? 26.51100  8.01600   9.46200   1.000 303.88000 ? 21  LEU B CB    1 
ATOM   4007 C  CG    . LEU B 2 21  ? 25.34200  7.08600   9.50300   1.000 315.99000 ? 21  LEU B CG    1 
ATOM   4008 C  CD1   . LEU B 2 21  ? 24.50600  7.41800   10.76000  1.000 315.94000 ? 21  LEU B CD1   1 
ATOM   4009 C  CD2   . LEU B 2 21  ? 24.59200  7.24700   8.21000   1.000 314.73000 ? 21  LEU B CD2   1 
ATOM   4010 N  N     . SER B 2 22  ? 28.74600  6.08000   9.75000   1.000 297.55000 ? 22  SER B N     1 
ATOM   4011 C  CA    . SER B 2 22  ? 29.34700  4.74900   9.70600   1.000 294.56000 ? 22  SER B CA    1 
ATOM   4012 C  C     . SER B 2 22  ? 29.89400  4.36000   11.06400  1.000 296.14000 ? 22  SER B C     1 
ATOM   4013 O  O     . SER B 2 22  ? 29.44600  3.37600   11.66700  1.000 296.62000 ? 22  SER B O     1 
ATOM   4014 C  CB    . SER B 2 22  ? 30.45700  4.67600   8.65800   1.000 287.80000 ? 22  SER B CB    1 
ATOM   4015 O  OG    . SER B 2 22  ? 30.81200  5.95400   8.17200   1.000 292.09000 ? 22  SER B OG    1 
ATOM   4016 N  N     . LEU B 2 23  ? 30.79000  5.17900   11.60700  1.000 293.34000 ? 23  LEU B N     1 
ATOM   4017 C  CA    . LEU B 2 23  ? 31.44600  4.78300   12.84100  1.000 299.74000 ? 23  LEU B CA    1 
ATOM   4018 C  C     . LEU B 2 23  ? 30.45500  4.66200   14.00200  1.000 298.07000 ? 23  LEU B C     1 
ATOM   4019 O  O     . LEU B 2 23  ? 30.55600  3.71700   14.79600  1.000 302.20000 ? 23  LEU B O     1 
ATOM   4020 C  CB    . LEU B 2 23  ? 32.59600  5.74800   13.15600  1.000 310.95000 ? 23  LEU B CB    1 
ATOM   4021 C  CG    . LEU B 2 23  ? 33.90800  5.64500   12.33300  1.000 310.01000 ? 23  LEU B CG    1 
ATOM   4022 C  CD1   . LEU B 2 23  ? 35.06300  6.28000   13.09000  1.000 313.58000 ? 23  LEU B CD1   1 
ATOM   4023 C  CD2   . LEU B 2 23  ? 34.31000  4.22400   11.90200  1.000 295.25000 ? 23  LEU B CD2   1 
ATOM   4024 N  N     . LYS B 2 24  ? 29.46400  5.55900   14.10300  1.000 287.74000 ? 24  LYS B N     1 
ATOM   4025 C  CA    . LYS B 2 24  ? 28.49600  5.36900   15.18000  1.000 279.55000 ? 24  LYS B CA    1 
ATOM   4026 C  C     . LYS B 2 24  ? 27.68200  4.11000   14.94200  1.000 281.48000 ? 24  LYS B C     1 
ATOM   4027 O  O     . LYS B 2 24  ? 27.27000  3.42600   15.89600  1.000 284.43000 ? 24  LYS B O     1 
ATOM   4028 C  CB    . LYS B 2 24  ? 27.58000  6.58200   15.30500  1.000 281.29000 ? 24  LYS B CB    1 
ATOM   4029 C  CG    . LYS B 2 24  ? 28.07500  7.62600   16.31000  1.000 280.39000 ? 24  LYS B CG    1 
ATOM   4030 C  CD    . LYS B 2 24  ? 27.44500  7.45900   17.67600  1.000 282.76000 ? 24  LYS B CD    1 
ATOM   4031 C  CE    . LYS B 2 24  ? 27.98000  8.50400   18.63600  1.000 289.56000 ? 24  LYS B CE    1 
ATOM   4032 N  NZ    . LYS B 2 24  ? 26.96800  8.88200   19.65200  1.000 294.72000 ? 24  LYS B NZ    1 
ATOM   4033 N  N     . LEU B 2 25  ? 27.46400  3.78400   13.66300  1.000 293.78000 ? 25  LEU B N     1 
ATOM   4034 C  CA    . LEU B 2 25  ? 26.75300  2.56000   13.31400  1.000 298.27000 ? 25  LEU B CA    1 
ATOM   4035 C  C     . LEU B 2 25  ? 27.60100  1.31900   13.55800  1.000 305.66000 ? 25  LEU B C     1 
ATOM   4036 O  O     . LEU B 2 25  ? 27.11800  0.32800   14.12600  1.000 307.62000 ? 25  LEU B O     1 
ATOM   4037 C  CB    . LEU B 2 25  ? 26.30900  2.61100   11.86000  1.000 297.62000 ? 25  LEU B CB    1 
ATOM   4038 C  CG    . LEU B 2 25  ? 25.11200  3.48300   11.50400  1.000 300.87000 ? 25  LEU B CG    1 
ATOM   4039 C  CD1   . LEU B 2 25  ? 24.35900  2.94100   10.28700  1.000 296.26000 ? 25  LEU B CD1   1 
ATOM   4040 C  CD2   . LEU B 2 25  ? 24.17900  3.60100   12.69100  1.000 303.31000 ? 25  LEU B CD2   1 
ATOM   4041 N  N     . ILE B 2 26  ? 28.86800  1.36000   13.14800  1.000 307.53000 ? 26  ILE B N     1 
ATOM   4042 C  CA    . ILE B 2 26  ? 29.71700  0.17600   13.23300  1.000 311.74000 ? 26  ILE B CA    1 
ATOM   4043 C  C     . ILE B 2 26  ? 29.88600  -0.23300  14.69400  1.000 311.11000 ? 26  ILE B C     1 
ATOM   4044 O  O     . ILE B 2 26  ? 29.81700  -1.42500  15.04100  1.000 306.83000 ? 26  ILE B O     1 
ATOM   4045 C  CB    . ILE B 2 26  ? 31.08100  0.44500   12.55000  1.000 312.94000 ? 26  ILE B CB    1 
ATOM   4046 C  CG1   . ILE B 2 26  ? 30.95000  0.65000   11.01700  1.000 307.58000 ? 26  ILE B CG1   1 
ATOM   4047 C  CG2   . ILE B 2 26  ? 32.07200  -0.67000  12.88800  1.000 314.33000 ? 26  ILE B CG2   1 
ATOM   4048 C  CD1   . ILE B 2 26  ? 32.09400  1.45800   10.33300  1.000 293.27000 ? 26  ILE B CD1   1 
ATOM   4049 N  N     . GLY B 2 27  ? 30.05700  0.76600   15.58300  1.000 306.87000 ? 27  GLY B N     1 
ATOM   4050 C  CA    . GLY B 2 27  ? 30.21100  0.48400   17.01000  1.000 305.04000 ? 27  GLY B CA    1 
ATOM   4051 C  C     . GLY B 2 27  ? 28.91000  0.04000   17.65700  1.000 305.39000 ? 27  GLY B C     1 
ATOM   4052 O  O     . GLY B 2 27  ? 28.91900  -0.64500  18.68500  1.000 313.14000 ? 27  GLY B O     1 
ATOM   4053 N  N     . LEU B 2 28  ? 27.76900  0.46300   17.08600  1.000 298.83000 ? 28  LEU B N     1 
ATOM   4054 C  CA    . LEU B 2 28  ? 26.46100  0.03800   17.57100  1.000 297.55000 ? 28  LEU B CA    1 
ATOM   4055 C  C     . LEU B 2 28  ? 26.17500  -1.42000  17.24800  1.000 307.84000 ? 28  LEU B C     1 
ATOM   4056 O  O     . LEU B 2 28  ? 25.34200  -2.01800  17.91900  1.000 311.32000 ? 28  LEU B O     1 
ATOM   4057 C  CB    . LEU B 2 28  ? 25.38500  0.94200   16.99200  1.000 290.16000 ? 28  LEU B CB    1 
ATOM   4058 C  CG    . LEU B 2 28  ? 25.12500  2.12700   17.91100  1.000 287.52000 ? 28  LEU B CG    1 
ATOM   4059 C  CD1   . LEU B 2 28  ? 24.22300  3.13000   17.24600  1.000 289.25000 ? 28  LEU B CD1   1 
ATOM   4060 C  CD2   . LEU B 2 28  ? 24.52400  1.62300   19.21400  1.000 285.15000 ? 28  LEU B CD2   1 
ATOM   4061 N  N     . GLY B 2 29  ? 26.85300  -2.00900  16.26200  1.000 301.59000 ? 29  GLY B N     1 
ATOM   4062 C  CA    . GLY B 2 29  ? 26.78900  -3.44000  15.97900  1.000 299.70000 ? 29  GLY B CA    1 
ATOM   4063 C  C     . GLY B 2 29  ? 26.55300  -3.77100  14.51600  1.000 293.60000 ? 29  GLY B C     1 
ATOM   4064 O  O     . GLY B 2 29  ? 26.64300  -4.94700  14.12000  1.000 297.17000 ? 29  GLY B O     1 
ATOM   4065 N  N     . TYR B 2 30  ? 26.32800  -2.76300  13.68900  1.000 298.76000 ? 30  TYR B N     1 
ATOM   4066 C  CA    . TYR B 2 30  ? 25.96200  -2.95400  12.30600  1.000 298.45000 ? 30  TYR B CA    1 
ATOM   4067 C  C     . TYR B 2 30  ? 27.21600  -3.23700  11.49900  1.000 296.10000 ? 30  TYR B C     1 
ATOM   4068 O  O     . TYR B 2 30  ? 28.33400  -2.97900  11.93200  1.000 297.44000 ? 30  TYR B O     1 
ATOM   4069 C  CB    . TYR B 2 30  ? 25.19300  -1.71500  11.84200  1.000 295.74000 ? 30  TYR B CB    1 
ATOM   4070 C  CG    . TYR B 2 30  ? 23.86400  -1.62500  12.58000  1.000 307.21000 ? 30  TYR B CG    1 
ATOM   4071 C  CD1   . TYR B 2 30  ? 22.76200  -2.32600  12.11300  1.000 314.86000 ? 30  TYR B CD1   1 
ATOM   4072 C  CD2   . TYR B 2 30  ? 23.72000  -0.90200  13.77800  1.000 309.94000 ? 30  TYR B CD2   1 
ATOM   4073 C  CE1   . TYR B 2 30  ? 21.54900  -2.30200  12.77700  1.000 317.57000 ? 30  TYR B CE1   1 
ATOM   4074 C  CE2   . TYR B 2 30  ? 22.47700  -0.87500  14.46300  1.000 307.65000 ? 30  TYR B CE2   1 
ATOM   4075 C  CZ    . TYR B 2 30  ? 21.40300  -1.58300  13.94300  1.000 306.16000 ? 30  TYR B CZ    1 
ATOM   4076 O  OH    . TYR B 2 30  ? 20.16800  -1.60700  14.54800  1.000 297.64000 ? 30  TYR B OH    1 
ATOM   4077 N  N     . GLU B 2 31  ? 27.02800  -3.83800  10.34800  1.000 294.91000 ? 31  GLU B N     1 
ATOM   4078 C  CA    . GLU B 2 31  ? 28.07900  -3.92800  9.34600   1.000 304.71000 ? 31  GLU B CA    1 
ATOM   4079 C  C     . GLU B 2 31  ? 27.80500  -2.83000  8.33300   1.000 311.66000 ? 31  GLU B C     1 
ATOM   4080 O  O     . GLU B 2 31  ? 26.72400  -2.80300  7.73500   1.000 311.84000 ? 31  GLU B O     1 
ATOM   4081 C  CB    . GLU B 2 31  ? 28.10700  -5.28200  8.64300   1.000 308.06000 ? 31  GLU B CB    1 
ATOM   4082 C  CG    . GLU B 2 31  ? 29.48900  -5.73600  8.28200   1.000 316.63000 ? 31  GLU B CG    1 
ATOM   4083 C  CD    . GLU B 2 31  ? 30.00100  -6.77200  9.24200   1.000 333.41000 ? 31  GLU B CD    1 
ATOM   4084 O  OE1   . GLU B 2 31  ? 29.44400  -7.88200  9.26800   1.000 329.48000 ? 31  GLU B OE1   1 
ATOM   4085 O  OE2   . GLU B 2 31  ? 30.95000  -6.47800  9.98700   1.000 345.02000 ? 31  GLU B OE2   1 
ATOM   4086 N  N     . VAL B 2 32  ? 28.76000  -1.91500  8.15600   1.000 328.59000 ? 32  VAL B N     1 
ATOM   4087 C  CA    . VAL B 2 32  ? 28.62500  -0.76800  7.25400   1.000 330.37000 ? 32  VAL B CA    1 
ATOM   4088 C  C     . VAL B 2 32  ? 29.67200  -0.87500  6.15200   1.000 327.06000 ? 32  VAL B C     1 
ATOM   4089 O  O     . VAL B 2 32  ? 30.87600  -0.93200  6.44300   1.000 327.48000 ? 32  VAL B O     1 
ATOM   4090 C  CB    . VAL B 2 32  ? 28.80100  0.56800   8.00400   1.000 323.21000 ? 32  VAL B CB    1 
ATOM   4091 C  CG1   . VAL B 2 32  ? 28.96800  1.74600   6.99300   1.000 311.42000 ? 32  VAL B CG1   1 
ATOM   4092 C  CG2   . VAL B 2 32  ? 27.65200  0.80900   8.96600   1.000 313.20000 ? 32  VAL B CG2   1 
ATOM   4093 N  N     . TRP B 2 33  ? 29.22100  -0.86600  4.89300   1.000 318.35000 ? 33  TRP B N     1 
ATOM   4094 C  CA    . TRP B 2 33  ? 30.11100  -0.76900  3.74500   1.000 307.95000 ? 33  TRP B CA    1 
ATOM   4095 C  C     . TRP B 2 33  ? 30.14500  0.68200   3.28300   1.000 305.46000 ? 33  TRP B C     1 
ATOM   4096 O  O     . TRP B 2 33  ? 29.10400  1.25100   2.95500   1.000 309.21000 ? 33  TRP B O     1 
ATOM   4097 C  CB    . TRP B 2 33  ? 29.67600  -1.69600  2.61100   1.000 304.02000 ? 33  TRP B CB    1 
ATOM   4098 C  CG    . TRP B 2 33  ? 30.86400  -2.09400  1.86200   1.000 312.17000 ? 33  TRP B CG    1 
ATOM   4099 C  CD1   . TRP B 2 33  ? 31.54600  -3.27000  1.96600   1.000 313.54000 ? 33  TRP B CD1   1 
ATOM   4100 C  CD2   . TRP B 2 33  ? 31.58800  -1.28700  0.93900   1.000 316.67000 ? 33  TRP B CD2   1 
ATOM   4101 N  NE1   . TRP B 2 33  ? 32.63800  -3.26000  1.13600   1.000 322.50000 ? 33  TRP B NE1   1 
ATOM   4102 C  CE2   . TRP B 2 33  ? 32.68500  -2.05200  0.49000   1.000 322.76000 ? 33  TRP B CE2   1 
ATOM   4103 C  CE3   . TRP B 2 33  ? 31.40800  0.00300   0.43300   1.000 314.47000 ? 33  TRP B CE3   1 
ATOM   4104 C  CZ2   . TRP B 2 33  ? 33.59300  -1.56900  -0.44500  1.000 322.62000 ? 33  TRP B CZ2   1 
ATOM   4105 C  CZ3   . TRP B 2 33  ? 32.30000  0.48200   -0.49100  1.000 314.77000 ? 33  TRP B CZ3   1 
ATOM   4106 C  CH2   . TRP B 2 33  ? 33.38400  -0.30300  -0.92800  1.000 316.31000 ? 33  TRP B CH2   1 
ATOM   4107 N  N     . CYS B 2 34  ? 31.33600  1.27600   3.27600   1.000 296.31000 ? 34  CYS B N     1 
ATOM   4108 C  CA    . CYS B 2 34  ? 31.52900  2.70400   3.09100   1.000 294.23000 ? 34  CYS B CA    1 
ATOM   4109 C  C     . CYS B 2 34  ? 32.87300  2.83500   2.40300   1.000 304.42000 ? 34  CYS B C     1 
ATOM   4110 O  O     . CYS B 2 34  ? 33.81000  2.12200   2.76800   1.000 309.50000 ? 34  CYS B O     1 
ATOM   4111 C  CB    . CYS B 2 34  ? 31.46500  3.39600   4.47000   1.000 292.93000 ? 34  CYS B CB    1 
ATOM   4112 S  SG    . CYS B 2 34  ? 31.26700  5.17500   4.67200   1.000 302.33000 ? 34  CYS B SG    1 
ATOM   4113 N  N     . ASP B 2 35  ? 32.95500  3.68800   1.36100   1.000 308.30000 ? 35  ASP B N     1 
ATOM   4114 C  CA    . ASP B 2 35  ? 34.25000  3.90700   0.70100   1.000 309.00000 ? 35  ASP B CA    1 
ATOM   4115 C  C     . ASP B 2 35  ? 35.28200  4.44000   1.67000   1.000 314.26000 ? 35  ASP B C     1 
ATOM   4116 O  O     . ASP B 2 35  ? 36.49200  4.38200   1.38300   1.000 306.92000 ? 35  ASP B O     1 
ATOM   4117 C  CB    . ASP B 2 35  ? 34.20000  4.92700   -0.44900  1.000 300.54000 ? 35  ASP B CB    1 
ATOM   4118 C  CG    . ASP B 2 35  ? 32.89600  4.92100   -1.21600  1.000 308.87000 ? 35  ASP B CG    1 
ATOM   4119 O  OD1   . ASP B 2 35  ? 31.96700  4.21300   -0.80300  1.000 305.44000 ? 35  ASP B OD1   1 
ATOM   4120 O  OD2   . ASP B 2 35  ? 32.81100  5.64700   -2.24100  1.000 317.78000 ? 35  ASP B OD2   1 
ATOM   4121 N  N     . ILE B 2 36  ? 34.79200  5.00500   2.77900   1.000 322.00000 ? 36  ILE B N     1 
ATOM   4122 C  CA    . ILE B 2 36  ? 35.61600  5.70300   3.75900   1.000 322.82000 ? 36  ILE B CA    1 
ATOM   4123 C  C     . ILE B 2 36  ? 36.63300  4.75500   4.37600   1.000 322.45000 ? 36  ILE B C     1 
ATOM   4124 O  O     . ILE B 2 36  ? 37.77200  5.13600   4.66000   1.000 323.68000 ? 36  ILE B O     1 
ATOM   4125 C  CB    . ILE B 2 36  ? 34.70500  6.34700   4.82400   1.000 323.21000 ? 36  ILE B CB    1 
ATOM   4126 C  CG1   . ILE B 2 36  ? 34.17300  7.69500   4.33300   1.000 318.59000 ? 36  ILE B CG1   1 
ATOM   4127 C  CG2   . ILE B 2 36  ? 35.39700  6.39200   6.20600   1.000 323.48000 ? 36  ILE B CG2   1 
ATOM   4128 C  CD1   . ILE B 2 36  ? 35.16800  8.82800   4.42700   1.000 301.89000 ? 36  ILE B CD1   1 
ATOM   4129 N  N     . LEU B 2 37  ? 36.26000  3.48600   4.52000   1.000 316.69000 ? 37  LEU B N     1 
ATOM   4130 C  CA    . LEU B 2 37  ? 37.07000  2.54300   5.28700   1.000 311.58000 ? 37  LEU B CA    1 
ATOM   4131 C  C     . LEU B 2 37  ? 38.18800  1.94000   4.43500   1.000 308.31000 ? 37  LEU B C     1 
ATOM   4132 O  O     . LEU B 2 37  ? 39.26300  1.63400   4.94400   1.000 310.59000 ? 37  LEU B O     1 
ATOM   4133 C  CB    . LEU B 2 37  ? 36.18800  1.42100   5.86800   1.000 299.77000 ? 37  LEU B CB    1 
ATOM   4134 C  CG    . LEU B 2 37  ? 34.86800  1.59300   6.65900   1.000 292.00000 ? 37  LEU B CG    1 
ATOM   4135 C  CD1   . LEU B 2 37  ? 34.69500  2.86500   7.52100   1.000 287.09000 ? 37  LEU B CD1   1 
ATOM   4136 C  CD2   . LEU B 2 37  ? 33.63100  1.41300   5.82500   1.000 296.01000 ? 37  LEU B CD2   1 
ATOM   4137 N  N     . PHE B 2 38  ? 37.99100  1.79400   3.14000   1.000 298.77000 ? 38  PHE B N     1 
ATOM   4138 C  CA    . PHE B 2 38  ? 38.97700  1.03400   2.40100   1.000 305.99000 ? 38  PHE B CA    1 
ATOM   4139 C  C     . PHE B 2 38  ? 40.00500  1.95400   1.78600   1.000 310.48000 ? 38  PHE B C     1 
ATOM   4140 O  O     . PHE B 2 38  ? 39.95300  3.17400   1.90600   1.000 304.95000 ? 38  PHE B O     1 
ATOM   4141 C  CB    . PHE B 2 38  ? 38.31100  0.20200   1.30900   1.000 306.30000 ? 38  PHE B CB    1 
ATOM   4142 C  CG    . PHE B 2 38  ? 37.19100  -0.63600  1.81900   1.000 305.45000 ? 38  PHE B CG    1 
ATOM   4143 C  CD1   . PHE B 2 38  ? 37.36100  -1.99200  1.97500   1.000 300.60000 ? 38  PHE B CD1   1 
ATOM   4144 C  CD2   . PHE B 2 38  ? 35.98100  -0.06800  2.17700   1.000 307.44000 ? 38  PHE B CD2   1 
ATOM   4145 C  CE1   . PHE B 2 38  ? 36.35000  -2.77400  2.45200   1.000 306.02000 ? 38  PHE B CE1   1 
ATOM   4146 C  CE2   . PHE B 2 38  ? 34.95800  -0.84500  2.66900   1.000 305.34000 ? 38  PHE B CE2   1 
ATOM   4147 C  CZ    . PHE B 2 38  ? 35.14400  -2.20800  2.80400   1.000 303.49000 ? 38  PHE B CZ    1 
ATOM   4148 N  N     . LEU B 2 39  ? 40.96700  1.34100   1.13300   1.000 299.79000 ? 39  LEU B N     1 
ATOM   4149 C  CA    . LEU B 2 39  ? 41.88400  2.05900   0.28700   1.000 307.74000 ? 39  LEU B CA    1 
ATOM   4150 C  C     . LEU B 2 39  ? 41.98200  1.25900   -1.01100  1.000 310.02000 ? 39  LEU B C     1 
ATOM   4151 O  O     . LEU B 2 39  ? 42.96900  0.57300   -1.27200  1.000 314.79000 ? 39  LEU B O     1 
ATOM   4152 C  CB    . LEU B 2 39  ? 43.24800  2.25600   0.96600   1.000 297.52000 ? 39  LEU B CB    1 
ATOM   4153 C  CG    . LEU B 2 39  ? 44.02800  1.05400   1.49500   1.000 305.14000 ? 39  LEU B CG    1 
ATOM   4154 C  CD1   . LEU B 2 39  ? 45.29500  0.99200   0.68000   1.000 297.90000 ? 39  LEU B CD1   1 
ATOM   4155 C  CD2   . LEU B 2 39  ? 44.34300  1.18800   2.96200   1.000 308.11000 ? 39  LEU B CD2   1 
ATOM   4156 N  N     . ASP B 2 40  ? 40.91200  1.30500   -1.80800  1.000 337.60000 ? 40  ASP B N     1 
ATOM   4157 C  CA    . ASP B 2 40  ? 40.79600  0.43900   -2.98100  1.000 343.52000 ? 40  ASP B CA    1 
ATOM   4158 C  C     . ASP B 2 40  ? 41.86400  0.77100   -4.01900  1.000 342.91000 ? 40  ASP B C     1 
ATOM   4159 O  O     . ASP B 2 40  ? 42.37400  1.89400   -4.07600  1.000 338.21000 ? 40  ASP B O     1 
ATOM   4160 C  CB    . ASP B 2 40  ? 39.39300  0.56300   -3.59700  1.000 342.73000 ? 40  ASP B CB    1 
ATOM   4161 C  CG    . ASP B 2 40  ? 38.79300  -0.79000  -3.98900  1.000 341.07000 ? 40  ASP B CG    1 
ATOM   4162 O  OD1   . ASP B 2 40  ? 39.57300  -1.70300  -4.34900  1.000 344.10000 ? 40  ASP B OD1   1 
ATOM   4163 O  OD2   . ASP B 2 40  ? 37.54900  -0.95000  -3.94100  1.000 335.62000 ? 40  ASP B OD2   1 
ATOM   4164 N  N     . LYS B 2 41  ? 42.19800  -0.23500  -4.83800  1.000 363.18000 ? 41  LYS B N     1 
ATOM   4165 C  CA    . LYS B 2 41  ? 43.25100  -0.16700  -5.84900  1.000 372.92000 ? 41  LYS B CA    1 
ATOM   4166 C  C     . LYS B 2 41  ? 42.92300  -1.05100  -7.06100  1.000 381.14000 ? 41  LYS B C     1 
ATOM   4167 O  O     . LYS B 2 41  ? 43.80200  -1.30300  -7.89900  1.000 390.80000 ? 41  LYS B O     1 
ATOM   4168 C  CB    . LYS B 2 41  ? 44.61900  -0.56000  -5.24000  1.000 380.11000 ? 41  LYS B CB    1 
ATOM   4169 C  CG    . LYS B 2 41  ? 45.87000  -0.25000  -6.12500  1.000 382.42000 ? 41  LYS B CG    1 
ATOM   4170 C  CD    . LYS B 2 41  ? 46.94800  -1.37600  -6.12700  1.000 383.58000 ? 41  LYS B CD    1 
ATOM   4171 C  CE    . LYS B 2 41  ? 46.37300  -2.79900  -6.36900  1.000 381.17000 ? 41  LYS B CE    1 
ATOM   4172 N  NZ    . LYS B 2 41  ? 47.37900  -3.92900  -6.33700  1.000 367.74000 ? 41  LYS B NZ    1 
ATOM   4173 N  N     . GLY B 2 42  ? 41.67900  -1.49800  -7.19800  1.000 380.31000 ? 42  GLY B N     1 
ATOM   4174 C  CA    . GLY B 2 42  ? 41.30100  -2.39300  -8.31200  1.000 380.01000 ? 42  GLY B CA    1 
ATOM   4175 C  C     . GLY B 2 42  ? 40.50400  -1.79200  -9.33100  1.000 382.22000 ? 42  GLY B C     1 
ATOM   4176 O  O     . GLY B 2 42  ? 39.95900  -0.65000  -9.25500  1.000 389.23000 ? 42  GLY B O     1 
ATOM   4177 N  N     . VAL B 2 43  ? 40.31300  -2.51900  -10.48600 1.000 384.73000 ? 43  VAL B N     1 
ATOM   4178 C  CA    . VAL B 2 43  ? 39.33700  -2.14500  -11.48300 1.000 383.21000 ? 43  VAL B CA    1 
ATOM   4179 C  C     . VAL B 2 43  ? 37.94500  -2.58100  -11.03000 1.000 388.47000 ? 43  VAL B C     1 
ATOM   4180 O  O     . VAL B 2 43  ? 36.91900  -2.05600  -11.48600 1.000 384.12000 ? 43  VAL B O     1 
ATOM   4181 C  CB    . VAL B 2 43  ? 39.73300  -2.70000  -12.87100 1.000 379.64000 ? 43  VAL B CB    1 
ATOM   4182 C  CG1   . VAL B 2 43  ? 41.15500  -2.19200  -13.30700 1.000 376.07000 ? 43  VAL B CG1   1 
ATOM   4183 C  CG2   . VAL B 2 43  ? 39.66300  -4.22200  -12.92500 1.000 382.68000 ? 43  VAL B CG2   1 
ATOM   4184 N  N     . ASP B 2 44  ? 37.91000  -3.51600  -10.07200 1.000 385.43000 ? 44  ASP B N     1 
ATOM   4185 C  CA    . ASP B 2 44  ? 36.70300  -4.01000  -9.41600  1.000 379.65000 ? 44  ASP B CA    1 
ATOM   4186 C  C     . ASP B 2 44  ? 36.28200  -3.12600  -8.26100  1.000 383.40000 ? 44  ASP B C     1 
ATOM   4187 O  O     . ASP B 2 44  ? 35.37000  -3.49900  -7.51300  1.000 377.69000 ? 44  ASP B O     1 
ATOM   4188 C  CB    . ASP B 2 44  ? 36.94800  -5.42800  -8.91000  1.000 374.22000 ? 44  ASP B CB    1 
ATOM   4189 C  CG    . ASP B 2 44  ? 38.07400  -5.49800  -7.88100  1.000 373.87000 ? 44  ASP B CG    1 
ATOM   4190 O  OD1   . ASP B 2 44  ? 39.25800  -5.50200  -8.28400  1.000 376.37000 ? 44  ASP B OD1   1 
ATOM   4191 O  OD2   . ASP B 2 44  ? 37.76700  -5.44500  -6.67200  1.000 365.87000 ? 44  ASP B OD2   1 
ATOM   4192 N  N     . PHE B 2 45  ? 36.98100  -1.99600  -8.08400  1.000 384.49000 ? 45  PHE B N     1 
ATOM   4193 C  CA    . PHE B 2 45  ? 36.63200  -1.02300  -7.05800  1.000 378.35000 ? 45  PHE B CA    1 
ATOM   4194 C  C     . PHE B 2 45  ? 35.16700  -0.68600  -7.17500  1.000 370.05000 ? 45  PHE B C     1 
ATOM   4195 O  O     . PHE B 2 45  ? 34.43900  -0.69400  -6.17700  1.000 362.31000 ? 45  PHE B O     1 
ATOM   4196 C  CB    . PHE B 2 45  ? 37.54000  0.24600   -7.12400  1.000 379.61000 ? 45  PHE B CB    1 
ATOM   4197 C  CG    . PHE B 2 45  ? 37.35700  1.18500   -8.37500  1.000 377.83000 ? 45  PHE B CG    1 
ATOM   4198 C  CD1   . PHE B 2 45  ? 37.17700  0.66700   -9.63700  1.000 380.27000 ? 45  PHE B CD1   1 
ATOM   4199 C  CD2   . PHE B 2 45  ? 37.44400  2.59500   -8.24800  1.000 370.34000 ? 45  PHE B CD2   1 
ATOM   4200 C  CE1   . PHE B 2 45  ? 37.02400  1.48300   -10.74400 1.000 369.28000 ? 45  PHE B CE1   1 
ATOM   4201 C  CE2   . PHE B 2 45  ? 37.29800  3.41000   -9.37000  1.000 369.28000 ? 45  PHE B CE2   1 
ATOM   4202 C  CZ    . PHE B 2 45  ? 37.08900  2.83700   -10.61100 1.000 371.84000 ? 45  PHE B CZ    1 
ATOM   4203 N  N     . TRP B 2 46  ? 34.71400  -0.45300  -8.40300  1.000 371.31000 ? 46  TRP B N     1 
ATOM   4204 C  CA    . TRP B 2 46  ? 33.30800  -0.20700  -8.65400  1.000 360.56000 ? 46  TRP B CA    1 
ATOM   4205 C  C     . TRP B 2 46  ? 32.52900  -1.51600  -8.54600  1.000 354.65000 ? 46  TRP B C     1 
ATOM   4206 O  O     . TRP B 2 46  ? 31.47000  -1.58800  -7.89700  1.000 350.72000 ? 46  TRP B O     1 
ATOM   4207 C  CB    . TRP B 2 46  ? 33.14500  0.42200   -10.04400 1.000 356.33000 ? 46  TRP B CB    1 
ATOM   4208 C  CG    . TRP B 2 46  ? 31.69400  0.85100   -10.38400 1.000 355.41000 ? 46  TRP B CG    1 
ATOM   4209 C  CD1   . TRP B 2 46  ? 30.64200  0.92700   -9.50900  1.000 354.73000 ? 46  TRP B CD1   1 
ATOM   4210 C  CD2   . TRP B 2 46  ? 31.15600  1.24000   -11.67800 1.000 358.18000 ? 46  TRP B CD2   1 
ATOM   4211 N  NE1   . TRP B 2 46  ? 29.50000  1.33100   -10.16300 1.000 351.74000 ? 46  TRP B NE1   1 
ATOM   4212 C  CE2   . TRP B 2 46  ? 29.78200  1.53300   -11.48700 1.000 359.89000 ? 46  TRP B CE2   1 
ATOM   4213 C  CE3   . TRP B 2 46  ? 31.69600  1.37000   -12.96400 1.000 362.21000 ? 46  TRP B CE3   1 
ATOM   4214 C  CZ2   . TRP B 2 46  ? 28.94000  1.94700   -12.52900 1.000 365.38000 ? 46  TRP B CZ2   1 
ATOM   4215 C  CZ3   . TRP B 2 46  ? 30.84300  1.78600   -14.01000 1.000 347.75000 ? 46  TRP B CZ3   1 
ATOM   4216 C  CH2   . TRP B 2 46  ? 29.48200  2.06800   -13.77400 1.000 348.32000 ? 46  TRP B CH2   1 
ATOM   4217 N  N     . SER B 2 47  ? 33.06900  -2.58800  -9.14500  1.000 357.91000 ? 47  SER B N     1 
ATOM   4218 C  CA    . SER B 2 47  ? 32.42500  -3.89800  -9.02700  1.000 349.56000 ? 47  SER B CA    1 
ATOM   4219 C  C     . SER B 2 47  ? 32.35900  -4.36800  -7.57800  1.000 347.39000 ? 47  SER B C     1 
ATOM   4220 O  O     . SER B 2 47  ? 31.34000  -4.94200  -7.16100  1.000 335.90000 ? 47  SER B O     1 
ATOM   4221 C  CB    . SER B 2 47  ? 33.14500  -4.93500  -9.89900  1.000 350.16000 ? 47  SER B CB    1 
ATOM   4222 O  OG    . SER B 2 47  ? 32.46800  -6.14000  -9.85000  1.000 367.62000 ? 47  SER B OG    1 
ATOM   4223 N  N     . THR B 2 48  ? 33.44700  -4.16800  -6.80900  1.000 359.34000 ? 48  THR B N     1 
ATOM   4224 C  CA    . THR B 2 48  ? 33.35500  -4.37300  -5.36900  1.000 351.93000 ? 48  THR B CA    1 
ATOM   4225 C  C     . THR B 2 48  ? 32.08700  -3.72700  -4.84200  1.000 348.69000 ? 48  THR B C     1 
ATOM   4226 O  O     . THR B 2 48  ? 31.18000  -4.44600  -4.41500  1.000 342.61000 ? 48  THR B O     1 
ATOM   4227 C  CB    . THR B 2 48  ? 34.58800  -3.85700  -4.59900  1.000 349.86000 ? 48  THR B CB    1 
ATOM   4228 O  OG1   . THR B 2 48  ? 34.95800  -2.55400  -5.02500  1.000 349.51000 ? 48  THR B OG1   1 
ATOM   4229 C  CG2   . THR B 2 48  ? 35.77200  -4.80000  -4.66300  1.000 348.69000 ? 48  THR B CG2   1 
ATOM   4230 N  N     . ILE B 2 49  ? 31.98000  -2.38700  -4.92900  1.000 347.95000 ? 49  ILE B N     1 
ATOM   4231 C  CA    . ILE B 2 49  ? 30.70700  -1.70000  -4.69300  1.000 347.33000 ? 49  ILE B CA    1 
ATOM   4232 C  C     . ILE B 2 49  ? 29.55900  -2.52600  -5.25800  1.000 342.71000 ? 49  ILE B C     1 
ATOM   4233 O  O     . ILE B 2 49  ? 28.81400  -3.15100  -4.50500  1.000 340.24000 ? 49  ILE B O     1 
ATOM   4234 C  CB    . ILE B 2 49  ? 30.73000  -0.26500  -5.28000  1.000 350.41000 ? 49  ILE B CB    1 
ATOM   4235 C  CG1   . ILE B 2 49  ? 32.05700  0.46600   -4.95200  1.000 344.97000 ? 49  ILE B CG1   1 
ATOM   4236 C  CG2   . ILE B 2 49  ? 29.48400  0.56700   -4.75500  1.000 338.82000 ? 49  ILE B CG2   1 
ATOM   4237 C  CD1   . ILE B 2 49  ? 32.25400  1.90300   -5.53900  1.000 339.07000 ? 49  ILE B CD1   1 
ATOM   4238 N  N     . GLU B 2 50  ? 29.48400  -2.66100  -6.58100  1.000 342.29000 ? 50  GLU B N     1 
ATOM   4239 C  CA    . GLU B 2 50  ? 28.36000  -3.38800  -7.16400  1.000 338.99000 ? 50  GLU B CA    1 
ATOM   4240 C  C     . GLU B 2 50  ? 28.17100  -4.74800  -6.52800  1.000 335.25000 ? 50  GLU B C     1 
ATOM   4241 O  O     . GLU B 2 50  ? 27.07300  -5.05000  -6.06600  1.000 337.12000 ? 50  GLU B O     1 
ATOM   4242 C  CB    . GLU B 2 50  ? 28.51000  -3.51500  -8.67400  1.000 342.30000 ? 50  GLU B CB    1 
ATOM   4243 C  CG    . GLU B 2 50  ? 27.61000  -2.53800  -9.37600  1.000 346.19000 ? 50  GLU B CG    1 
ATOM   4244 C  CD    . GLU B 2 50  ? 27.68700  -2.61700  -10.86800 1.000 356.26000 ? 50  GLU B CD    1 
ATOM   4245 O  OE1   . GLU B 2 50  ? 28.28300  -1.69300  -11.48100 1.000 363.11000 ? 50  GLU B OE1   1 
ATOM   4246 O  OE2   . GLU B 2 50  ? 27.13400  -3.59600  -11.43100 1.000 366.09000 ? 50  GLU B OE2   1 
ATOM   4247 N  N     . LYS B 2 51  ? 29.21600  -5.56600  -6.46500  1.000 327.56000 ? 51  LYS B N     1 
ATOM   4248 C  CA    . LYS B 2 51  ? 29.05800  -6.85500  -5.81800  1.000 326.50000 ? 51  LYS B CA    1 
ATOM   4249 C  C     . LYS B 2 51  ? 28.42200  -6.69500  -4.45300  1.000 326.77000 ? 51  LYS B C     1 
ATOM   4250 O  O     . LYS B 2 51  ? 27.45000  -7.38700  -4.12500  1.000 331.36000 ? 51  LYS B O     1 
ATOM   4251 C  CB    . LYS B 2 51  ? 30.39500  -7.54800  -5.69800  1.000 321.64000 ? 51  LYS B CB    1 
ATOM   4252 C  CG    . LYS B 2 51  ? 30.54400  -8.63200  -6.70800  1.000 333.18000 ? 51  LYS B CG    1 
ATOM   4253 C  CD    . LYS B 2 51  ? 31.42600  -9.70700  -6.16400  1.000 335.99000 ? 51  LYS B CD    1 
ATOM   4254 C  CE    . LYS B 2 51  ? 31.77500  -10.68900 -7.25000  1.000 340.72000 ? 51  LYS B CE    1 
ATOM   4255 N  NZ    . LYS B 2 51  ? 31.38400  -12.06600 -6.85900  1.000 336.94000 ? 51  LYS B NZ    1 
ATOM   4256 N  N     . GLU B 2 52  ? 28.92600  -5.75100  -3.65300  1.000 335.12000 ? 52  GLU B N     1 
ATOM   4257 C  CA    . GLU B 2 52  ? 28.40900  -5.62900  -2.29100  1.000 341.32000 ? 52  GLU B CA    1 
ATOM   4258 C  C     . GLU B 2 52  ? 26.97900  -5.09900  -2.26700  1.000 343.01000 ? 52  GLU B C     1 
ATOM   4259 O  O     . GLU B 2 52  ? 26.13700  -5.63800  -1.53500  1.000 345.83000 ? 52  GLU B O     1 
ATOM   4260 C  CB    . GLU B 2 52  ? 29.32600  -4.75700  -1.41900  1.000 347.55000 ? 52  GLU B CB    1 
ATOM   4261 C  CG    . GLU B 2 52  ? 30.82400  -5.22600  -1.24500  1.000 346.31000 ? 52  GLU B CG    1 
ATOM   4262 C  CD    . GLU B 2 52  ? 31.10400  -6.18100  -0.05500  1.000 338.29000 ? 52  GLU B CD    1 
ATOM   4263 O  OE1   . GLU B 2 52  ? 30.15100  -6.74200  0.53900   1.000 332.93000 ? 52  GLU B OE1   1 
ATOM   4264 O  OE2   . GLU B 2 52  ? 32.30000  -6.39000  0.30100   1.000 337.74000 ? 52  GLU B OE2   1 
ATOM   4265 N  N     . ILE B 2 53  ? 26.67600  -4.04300  -3.03000  1.000 339.65000 ? 53  ILE B N     1 
ATOM   4266 C  CA    . ILE B 2 53  ? 25.28900  -3.58900  -3.01400  1.000 336.99000 ? 53  ILE B CA    1 
ATOM   4267 C  C     . ILE B 2 53  ? 24.39300  -4.71100  -3.54000  1.000 337.89000 ? 53  ILE B C     1 
ATOM   4268 O  O     . ILE B 2 53  ? 23.30100  -4.96700  -2.99700  1.000 337.45000 ? 53  ILE B O     1 
ATOM   4269 C  CB    . ILE B 2 53  ? 25.04800  -2.28800  -3.81800  1.000 336.54000 ? 53  ILE B CB    1 
ATOM   4270 C  CG1   . ILE B 2 53  ? 26.22200  -1.29700  -3.79800  1.000 333.67000 ? 53  ILE B CG1   1 
ATOM   4271 C  CG2   . ILE B 2 53  ? 23.65600  -1.68300  -3.39300  1.000 333.83000 ? 53  ILE B CG2   1 
ATOM   4272 C  CD1   . ILE B 2 53  ? 26.11100  -0.15300  -4.85000  1.000 333.29000 ? 53  ILE B CD1   1 
ATOM   4273 N  N     . ARG B 2 54  ? 24.88300  -5.44100  -4.55900  1.000 337.49000 ? 54  ARG B N     1 
ATOM   4274 C  CA    . ARG B 2 54  ? 24.12500  -6.53000  -5.17200  1.000 341.87000 ? 54  ARG B CA    1 
ATOM   4275 C  C     . ARG B 2 54  ? 23.72000  -7.56100  -4.12800  1.000 337.92000 ? 54  ARG B C     1 
ATOM   4276 O  O     . ARG B 2 54  ? 22.54400  -7.73900  -3.82000  1.000 335.14000 ? 54  ARG B O     1 
ATOM   4277 C  CB    . ARG B 2 54  ? 24.97400  -7.18200  -6.29100  1.000 343.44000 ? 54  ARG B CB    1 
ATOM   4278 C  CG    . ARG B 2 54  ? 24.20800  -7.98400  -7.38400  1.000 356.05000 ? 54  ARG B CG    1 
ATOM   4279 C  CD    . ARG B 2 54  ? 24.39000  -7.38300  -8.82000  1.000 360.05000 ? 54  ARG B CD    1 
ATOM   4280 N  NE    . ARG B 2 54  ? 23.95000  -8.28300  -9.89800  1.000 366.35000 ? 54  ARG B NE    1 
ATOM   4281 C  CZ    . ARG B 2 54  ? 22.67500  -8.57600  -10.15700 1.000 369.94000 ? 54  ARG B CZ    1 
ATOM   4282 N  NH1   . ARG B 2 54  ? 21.71700  -8.03000  -9.42300  1.000 372.11000 ? 54  ARG B NH1   1 
ATOM   4283 N  NH2   . ARG B 2 54  ? 22.35000  -9.41900  -11.13300 1.000 372.51000 ? 54  ARG B NH2   1 
ATOM   4284 N  N     . GLU B 2 55  ? 24.69100  -8.22900  -3.54200  1.000 325.11000 ? 55  GLU B N     1 
ATOM   4285 C  CA    . GLU B 2 55  ? 24.40000  -9.45500  -2.81500  1.000 329.50000 ? 55  GLU B CA    1 
ATOM   4286 C  C     . GLU B 2 55  ? 24.14400  -9.20400  -1.33900  1.000 333.56000 ? 55  GLU B C     1 
ATOM   4287 O  O     . GLU B 2 55  ? 23.02100  -9.36500  -0.84600  1.000 329.05000 ? 55  GLU B O     1 
ATOM   4288 C  CB    . GLU B 2 55  ? 25.55700  -10.40700 -2.95000  1.000 331.96000 ? 55  GLU B CB    1 
ATOM   4289 C  CG    . GLU B 2 55  ? 25.70400  -10.98200 -4.32300  1.000 342.05000 ? 55  GLU B CG    1 
ATOM   4290 C  CD    . GLU B 2 55  ? 25.93400  -12.45100 -4.22000  1.000 353.03000 ? 55  GLU B CD    1 
ATOM   4291 O  OE1   . GLU B 2 55  ? 24.95700  -13.17300 -3.95000  1.000 356.22000 ? 55  GLU B OE1   1 
ATOM   4292 O  OE2   . GLU B 2 55  ? 27.09800  -12.87800 -4.32600  1.000 361.63000 ? 55  GLU B OE2   1 
ATOM   4293 N  N     . ASN B 2 56  ? 25.18300  -8.77400  -0.64600  1.000 335.14000 ? 56  ASN B N     1 
ATOM   4294 C  CA    . ASN B 2 56  ? 25.25000  -8.71800  0.79100   1.000 330.96000 ? 56  ASN B CA    1 
ATOM   4295 C  C     . ASN B 2 56  ? 24.71300  -7.42700  1.38300   1.000 330.02000 ? 56  ASN B C     1 
ATOM   4296 O  O     . ASN B 2 56  ? 24.74600  -7.28100  2.60000   1.000 339.41000 ? 56  ASN B O     1 
ATOM   4297 C  CB    . ASN B 2 56  ? 26.71000  -8.89700  1.23300   1.000 328.94000 ? 56  ASN B CB    1 
ATOM   4298 C  CG    . ASN B 2 56  ? 26.94100  -10.21600 1.91900   1.000 341.07000 ? 56  ASN B CG    1 
ATOM   4299 O  OD1   . ASN B 2 56  ? 26.60900  -11.27200 1.39200   1.000 346.06000 ? 56  ASN B OD1   1 
ATOM   4300 N  ND2   . ASN B 2 56  ? 27.53200  -10.16300 3.10200   1.000 330.47000 ? 56  ASN B ND2   1 
ATOM   4301 N  N     . THR B 2 57  ? 24.25600  -6.46700  0.59600   1.000 333.63000 ? 57  THR B N     1 
ATOM   4302 C  CA    . THR B 2 57  ? 23.79700  -5.20600  1.18300   1.000 334.05000 ? 57  THR B CA    1 
ATOM   4303 C  C     . THR B 2 57  ? 22.33700  -5.35500  1.61600   1.000 334.01000 ? 57  THR B C     1 
ATOM   4304 O  O     . THR B 2 57  ? 21.44100  -5.46300  0.76900   1.000 323.81000 ? 57  THR B O     1 
ATOM   4305 C  CB    . THR B 2 57  ? 24.00600  -4.04100  0.21600   1.000 325.56000 ? 57  THR B CB    1 
ATOM   4306 O  OG1   . THR B 2 57  ? 25.41400  -3.81900  0.06600   1.000 324.71000 ? 57  THR B OG1   1 
ATOM   4307 C  CG2   . THR B 2 57  ? 23.34800  -2.74500  0.72200   1.000 318.38000 ? 57  THR B CG2   1 
ATOM   4308 N  N     . CYS B 2 58  ? 22.11700  -5.43300  2.94500   1.000 339.42000 ? 58  CYS B N     1 
ATOM   4309 C  CA    . CYS B 2 58  ? 20.77500  -5.38300  3.53300   1.000 337.16000 ? 58  CYS B CA    1 
ATOM   4310 C  C     . CYS B 2 58  ? 20.13300  -4.00400  3.35300   1.000 338.12000 ? 58  CYS B C     1 
ATOM   4311 O  O     . CYS B 2 58  ? 18.99000  -3.90700  2.89800   1.000 338.31000 ? 58  CYS B O     1 
ATOM   4312 C  CB    . CYS B 2 58  ? 20.89300  -5.74000  5.02000   1.000 332.56000 ? 58  CYS B CB    1 
ATOM   4313 S  SG    . CYS B 2 58  ? 19.44400  -5.61000  6.03900   1.000 321.96000 ? 58  CYS B SG    1 
ATOM   4314 N  N     . LYS B 2 59  ? 20.86400  -2.92000  3.67100   1.000 342.68000 ? 59  LYS B N     1 
ATOM   4315 C  CA    . LYS B 2 59  ? 20.35500  -1.54400  3.60600   1.000 341.80000 ? 59  LYS B CA    1 
ATOM   4316 C  C     . LYS B 2 59  ? 21.27500  -0.63200  2.79600   1.000 330.96000 ? 59  LYS B C     1 
ATOM   4317 O  O     . LYS B 2 59  ? 22.49100  -0.59000  3.01800   1.000 323.66000 ? 59  LYS B O     1 
ATOM   4318 C  CB    . LYS B 2 59  ? 20.16200  -0.94600  5.01700   1.000 328.13000 ? 59  LYS B CB    1 
ATOM   4319 C  CG    . LYS B 2 59  ? 18.68200  -0.84800  5.54300   1.000 318.32000 ? 59  LYS B CG    1 
ATOM   4320 C  CD    . LYS B 2 59  ? 17.87000  -2.14600  5.25800   1.000 318.94000 ? 59  LYS B CD    1 
ATOM   4321 C  CE    . LYS B 2 59  ? 16.45900  -2.21500  5.91200   1.000 313.47000 ? 59  LYS B CE    1 
ATOM   4322 N  NZ    . LYS B 2 59  ? 16.08300  -3.68000  6.01300   1.000 328.52000 ? 59  LYS B NZ    1 
ATOM   4323 N  N     . PHE B 2 60  ? 20.66800  0.10900   1.87300   1.000 333.07000 ? 60  PHE B N     1 
ATOM   4324 C  CA    . PHE B 2 60  ? 21.32600  1.20000   1.18000   1.000 324.01000 ? 60  PHE B CA    1 
ATOM   4325 C  C     . PHE B 2 60  ? 21.02900  2.49400   1.92100   1.000 318.66000 ? 60  PHE B C     1 
ATOM   4326 O  O     . PHE B 2 60  ? 19.88700  2.96100   1.94700   1.000 319.11000 ? 60  PHE B O     1 
ATOM   4327 C  CB    . PHE B 2 60  ? 20.85100  1.31200   -0.26300  1.000 329.01000 ? 60  PHE B CB    1 
ATOM   4328 C  CG    . PHE B 2 60  ? 21.73500  2.17500   -1.13000  1.000 326.33000 ? 60  PHE B CG    1 
ATOM   4329 C  CD1   . PHE B 2 60  ? 21.55100  3.55600   -1.22700  1.000 322.45000 ? 60  PHE B CD1   1 
ATOM   4330 C  CD2   . PHE B 2 60  ? 22.75200  1.59500   -1.85800  1.000 326.61000 ? 60  PHE B CD2   1 
ATOM   4331 C  CE1   . PHE B 2 60  ? 22.37900  4.32300   -2.04300  1.000 320.62000 ? 60  PHE B CE1   1 
ATOM   4332 C  CE2   . PHE B 2 60  ? 23.57300  2.35100   -2.66200  1.000 327.37000 ? 60  PHE B CE2   1 
ATOM   4333 C  CZ    . PHE B 2 60  ? 23.38800  3.71000   -2.76100  1.000 325.73000 ? 60  PHE B CZ    1 
ATOM   4334 N  N     . LEU B 2 61  ? 22.05100  3.06800   2.52300   1.000 315.69000 ? 61  LEU B N     1 
ATOM   4335 C  CA    . LEU B 2 61  ? 21.96800  4.41300   3.06200   1.000 315.54000 ? 61  LEU B CA    1 
ATOM   4336 C  C     . LEU B 2 61  ? 22.64400  5.36000   2.07700   1.000 318.84000 ? 61  LEU B C     1 
ATOM   4337 O  O     . LEU B 2 61  ? 23.79900  5.13500   1.70100   1.000 319.20000 ? 61  LEU B O     1 
ATOM   4338 C  CB    . LEU B 2 61  ? 22.64000  4.45800   4.43200   1.000 308.24000 ? 61  LEU B CB    1 
ATOM   4339 C  CG    . LEU B 2 61  ? 22.07100  3.44400   5.42000   1.000 300.70000 ? 61  LEU B CG    1 
ATOM   4340 C  CD1   . LEU B 2 61  ? 22.40500  3.91200   6.79700   1.000 296.68000 ? 61  LEU B CD1   1 
ATOM   4341 C  CD2   . LEU B 2 61  ? 20.57300  3.28100   5.27600   1.000 309.33000 ? 61  LEU B CD2   1 
ATOM   4342 N  N     . ILE B 2 62  ? 21.92500  6.38800   1.62200   1.000 317.64000 ? 62  ILE B N     1 
ATOM   4343 C  CA    . ILE B 2 62  ? 22.51300  7.41200   0.76300   1.000 316.44000 ? 62  ILE B CA    1 
ATOM   4344 C  C     . ILE B 2 62  ? 22.48400  8.73800   1.50700   1.000 317.00000 ? 62  ILE B C     1 
ATOM   4345 O  O     . ILE B 2 62  ? 21.45200  9.10500   2.07900   1.000 315.74000 ? 62  ILE B O     1 
ATOM   4346 C  CB    . ILE B 2 62  ? 21.78800  7.54700   -0.58800  1.000 314.75000 ? 62  ILE B CB    1 
ATOM   4347 C  CG1   . ILE B 2 62  ? 22.41000  8.72300   -1.34400  1.000 314.85000 ? 62  ILE B CG1   1 
ATOM   4348 C  CG2   . ILE B 2 62  ? 20.30400  7.77300   -0.37300  1.000 312.26000 ? 62  ILE B CG2   1 
ATOM   4349 C  CD1   . ILE B 2 62  ? 21.73900  9.11000   -2.64000  1.000 313.36000 ? 62  ILE B CD1   1 
ATOM   4350 N  N     . VAL B 2 63  ? 23.61700  9.44600   1.51600   1.000 316.51000 ? 63  VAL B N     1 
ATOM   4351 C  CA    . VAL B 2 63  ? 23.64500  10.81600  2.02100   1.000 320.82000 ? 63  VAL B CA    1 
ATOM   4352 C  C     . VAL B 2 63  ? 22.80600  11.68100  1.09300   1.000 323.93000 ? 63  VAL B C     1 
ATOM   4353 O  O     . VAL B 2 63  ? 23.07300  11.76300  -0.11300  1.000 322.09000 ? 63  VAL B O     1 
ATOM   4354 C  CB    . VAL B 2 63  ? 25.09000  11.33400  2.16200   1.000 318.82000 ? 63  VAL B CB    1 
ATOM   4355 C  CG1   . VAL B 2 63  ? 25.15500  12.90000  2.33400   1.000 320.21000 ? 63  VAL B CG1   1 
ATOM   4356 C  CG2   . VAL B 2 63  ? 25.76300  10.57800  3.31000   1.000 311.78000 ? 63  VAL B CG2   1 
ATOM   4357 N  N     . SER B 2 64  ? 21.74700  12.28000  1.64500   1.000 328.37000 ? 64  SER B N     1 
ATOM   4358 C  CA    . SER B 2 64  ? 20.85300  13.16100  0.88800   1.000 327.33000 ? 64  SER B CA    1 
ATOM   4359 C  C     . SER B 2 64  ? 21.25200  14.61900  1.12700   1.000 323.25000 ? 64  SER B C     1 
ATOM   4360 O  O     . SER B 2 64  ? 20.52900  15.42500  1.72200   1.000 314.38000 ? 64  SER B O     1 
ATOM   4361 C  CB    . SER B 2 64  ? 19.39600  12.90300  1.25700   1.000 324.17000 ? 64  SER B CB    1 
ATOM   4362 O  OG    . SER B 2 64  ? 18.54400  13.38500  0.23700   1.000 325.41000 ? 64  SER B OG    1 
ATOM   4363 N  N     . SER B 2 65  ? 22.44400  14.94200  0.64400   1.000 322.42000 ? 65  SER B N     1 
ATOM   4364 C  CA    . SER B 2 65  ? 22.90900  16.31200  0.55900   1.000 319.33000 ? 65  SER B CA    1 
ATOM   4365 C  C     . SER B 2 65  ? 22.64300  16.84400  -0.84100  1.000 319.41000 ? 65  SER B C     1 
ATOM   4366 O  O     . SER B 2 65  ? 22.24200  16.10700  -1.74900  1.000 318.03000 ? 65  SER B O     1 
ATOM   4367 C  CB    . SER B 2 65  ? 24.40300  16.40300  0.89000   1.000 325.23000 ? 65  SER B CB    1 
ATOM   4368 O  OG    . SER B 2 65  ? 25.16200  15.45300  0.14900   1.000 325.62000 ? 65  SER B OG    1 
ATOM   4369 N  N     . THR B 2 66  ? 22.86000  18.14600  -1.00400  1.000 315.00000 ? 66  THR B N     1 
ATOM   4370 C  CA    . THR B 2 66  ? 22.86800  18.71000  -2.34700  1.000 317.11000 ? 66  THR B CA    1 
ATOM   4371 C  C     . THR B 2 66  ? 23.93000  18.04800  -3.19400  1.000 318.65000 ? 66  THR B C     1 
ATOM   4372 O  O     . THR B 2 66  ? 23.67700  17.67400  -4.34700  1.000 315.73000 ? 66  THR B O     1 
ATOM   4373 C  CB    . THR B 2 66  ? 23.14200  20.20900  -2.28100  1.000 320.12000 ? 66  THR B CB    1 
ATOM   4374 O  OG1   . THR B 2 66  ? 22.28400  20.79700  -1.29400  1.000 325.67000 ? 66  THR B OG1   1 
ATOM   4375 C  CG2   . THR B 2 66  ? 22.99900  20.87700  -3.66800  1.000 317.10000 ? 66  THR B CG2   1 
ATOM   4376 N  N     . ALA B 2 67  ? 25.14300  17.94000  -2.65200  1.000 325.95000 ? 67  ALA B N     1 
ATOM   4377 C  CA    . ALA B 2 67  ? 26.22800  17.36200  -3.42400  1.000 325.68000 ? 67  ALA B CA    1 
ATOM   4378 C  C     . ALA B 2 67  ? 25.96800  15.89200  -3.69900  1.000 328.28000 ? 67  ALA B C     1 
ATOM   4379 O  O     . ALA B 2 67  ? 26.34100  15.38700  -4.76400  1.000 332.81000 ? 67  ALA B O     1 
ATOM   4380 C  CB    . ALA B 2 67  ? 27.55600  17.53700  -2.68100  1.000 322.12000 ? 67  ALA B CB    1 
ATOM   4381 N  N     . GLY B 2 68  ? 25.29800  15.19700  -2.76000  1.000 327.92000 ? 68  GLY B N     1 
ATOM   4382 C  CA    . GLY B 2 68  ? 25.09800  13.76400  -2.90900  1.000 323.14000 ? 68  GLY B CA    1 
ATOM   4383 C  C     . GLY B 2 68  ? 24.11100  13.41800  -4.01000  1.000 317.76000 ? 68  GLY B C     1 
ATOM   4384 O  O     . GLY B 2 68  ? 24.27300  12.41400  -4.72200  1.000 317.13000 ? 68  GLY B O     1 
ATOM   4385 N  N     . ASN B 2 69  ? 23.06300  14.22600  -4.16400  1.000 306.24000 ? 69  ASN B N     1 
ATOM   4386 C  CA    . ASN B 2 69  ? 22.12900  13.92500  -5.23600  1.000 305.53000 ? 69  ASN B CA    1 
ATOM   4387 C  C     . ASN B 2 69  ? 22.69200  14.34400  -6.59200  1.000 312.24000 ? 69  ASN B C     1 
ATOM   4388 O  O     . ASN B 2 69  ? 22.38200  13.71700  -7.60400  1.000 313.24000 ? 69  ASN B O     1 
ATOM   4389 C  CB    . ASN B 2 69  ? 20.79800  14.58100  -4.90400  1.000 313.14000 ? 69  ASN B CB    1 
ATOM   4390 C  CG    . ASN B 2 69  ? 20.36400  14.22300  -3.49500  1.000 321.20000 ? 69  ASN B CG    1 
ATOM   4391 O  OD1   . ASN B 2 69  ? 19.91300  13.11800  -3.24800  1.000 325.73000 ? 69  ASN B OD1   1 
ATOM   4392 N  ND2   . ASN B 2 69  ? 20.53900  15.14200  -2.56100  1.000 319.24000 ? 69  ASN B ND2   1 
ATOM   4393 N  N     . LYS B 2 70  ? 23.58600  15.34500  -6.62600  1.000 323.93000 ? 70  LYS B N     1 
ATOM   4394 C  CA    . LYS B 2 70  ? 24.20600  15.83700  -7.85600  1.000 325.60000 ? 70  LYS B CA    1 
ATOM   4395 C  C     . LYS B 2 70  ? 25.52500  15.14900  -8.20600  1.000 320.10000 ? 70  LYS B C     1 
ATOM   4396 O  O     . LYS B 2 70  ? 26.16600  15.52100  -9.20000  1.000 309.92000 ? 70  LYS B O     1 
ATOM   4397 C  CB    . LYS B 2 70  ? 24.44200  17.35000  -7.74700  1.000 327.90000 ? 70  LYS B CB    1 
ATOM   4398 C  CG    . LYS B 2 70  ? 23.44400  18.20000  -8.53200  1.000 320.44000 ? 70  LYS B CG    1 
ATOM   4399 C  CD    . LYS B 2 70  ? 22.62300  19.11200  -7.63600  1.000 316.01000 ? 70  LYS B CD    1 
ATOM   4400 C  CE    . LYS B 2 70  ? 21.95600  20.20200  -8.46400  1.000 315.35000 ? 70  LYS B CE    1 
ATOM   4401 N  NZ    . LYS B 2 70  ? 20.88600  20.88200  -7.69700  1.000 326.43000 ? 70  LYS B NZ    1 
ATOM   4402 N  N     . ARG B 2 71  ? 25.94400  14.16200  -7.43400  1.000 319.06000 ? 71  ARG B N     1 
ATOM   4403 C  CA    . ARG B 2 71  ? 27.26600  13.58600  -7.61300  1.000 316.02000 ? 71  ARG B CA    1 
ATOM   4404 C  C     . ARG B 2 71  ? 27.20000  12.39500  -8.54800  1.000 315.31000 ? 71  ARG B C     1 
ATOM   4405 O  O     . ARG B 2 71  ? 26.43300  11.45500  -8.32600  1.000 316.03000 ? 71  ARG B O     1 
ATOM   4406 C  CB    . ARG B 2 71  ? 27.85200  13.16100  -6.27100  1.000 320.58000 ? 71  ARG B CB    1 
ATOM   4407 C  CG    . ARG B 2 71  ? 29.36700  13.05200  -6.23100  1.000 312.28000 ? 71  ARG B CG    1 
ATOM   4408 C  CD    . ARG B 2 71  ? 29.87700  13.64900  -4.95000  1.000 317.65000 ? 71  ARG B CD    1 
ATOM   4409 N  NE    . ARG B 2 71  ? 31.24800  14.10900  -5.08900  1.000 317.83000 ? 71  ARG B NE    1 
ATOM   4410 C  CZ    . ARG B 2 71  ? 31.59200  15.37000  -5.32500  1.000 325.59000 ? 71  ARG B CZ    1 
ATOM   4411 N  NH1   . ARG B 2 71  ? 30.65700  16.30000  -5.45900  1.000 322.62000 ? 71  ARG B NH1   1 
ATOM   4412 N  NH2   . ARG B 2 71  ? 32.87300  15.69300  -5.42600  1.000 340.56000 ? 71  ARG B NH2   1 
ATOM   4413 N  N     . GLU B 2 72  ? 27.98700  12.46200  -9.61700  1.000 309.24000 ? 72  GLU B N     1 
ATOM   4414 C  CA    . GLU B 2 72  ? 28.02200  11.37700  -10.58400 1.000 317.47000 ? 72  GLU B CA    1 
ATOM   4415 C  C     . GLU B 2 72  ? 28.31500  10.03900  -9.91100  1.000 332.96000 ? 72  GLU B C     1 
ATOM   4416 O  O     . GLU B 2 72  ? 27.69800  9.01700   -10.24500 1.000 335.53000 ? 72  GLU B O     1 
ATOM   4417 C  CB    . GLU B 2 72  ? 29.06700  11.66700  -11.63100 1.000 320.70000 ? 72  GLU B CB    1 
ATOM   4418 C  CG    . GLU B 2 72  ? 29.31300  10.49800  -12.50700 1.000 329.27000 ? 72  GLU B CG    1 
ATOM   4419 C  CD    . GLU B 2 72  ? 29.56800  10.93500  -13.88900 1.000 335.04000 ? 72  GLU B CD    1 
ATOM   4420 O  OE1   . GLU B 2 72  ? 29.62500  10.06700  -14.77300 1.000 339.32000 ? 72  GLU B OE1   1 
ATOM   4421 O  OE2   . GLU B 2 72  ? 29.69400  12.15900  -14.08400 1.000 328.18000 ? 72  GLU B OE2   1 
ATOM   4422 N  N     . GLY B 2 73  ? 29.25000  10.03100  -8.94300  1.000 350.82000 ? 73  GLY B N     1 
ATOM   4423 C  CA    . GLY B 2 73  ? 29.64100  8.77700   -8.30100  1.000 345.12000 ? 73  GLY B CA    1 
ATOM   4424 C  C     . GLY B 2 73  ? 28.55200  8.21300   -7.40300  1.000 344.71000 ? 73  GLY B C     1 
ATOM   4425 O  O     . GLY B 2 73  ? 28.36800  6.99400   -7.31200  1.000 348.63000 ? 73  GLY B O     1 
ATOM   4426 N  N     . VAL B 2 74  ? 27.80200  9.09700   -6.73500  1.000 348.61000 ? 74  VAL B N     1 
ATOM   4427 C  CA    . VAL B 2 74  ? 26.69800  8.66000   -5.87600  1.000 341.01000 ? 74  VAL B CA    1 
ATOM   4428 C  C     . VAL B 2 74  ? 25.47400  8.32300   -6.71600  1.000 328.58000 ? 74  VAL B C     1 
ATOM   4429 O  O     . VAL B 2 74  ? 24.73100  7.37700   -6.41300  1.000 324.94000 ? 74  VAL B O     1 
ATOM   4430 C  CB    . VAL B 2 74  ? 26.39800  9.74100   -4.81400  1.000 338.66000 ? 74  VAL B CB    1 
ATOM   4431 C  CG1   . VAL B 2 74  ? 25.19300  9.38200   -3.94900  1.000 330.12000 ? 74  VAL B CG1   1 
ATOM   4432 C  CG2   . VAL B 2 74  ? 27.62300  9.95100   -3.94800  1.000 334.54000 ? 74  VAL B CG2   1 
ATOM   4433 N  N     . LEU B 2 75  ? 25.25300  9.06800   -7.79400  1.000 316.45000 ? 75  LEU B N     1 
ATOM   4434 C  CA    . LEU B 2 75  ? 24.18600  8.68800   -8.70000  1.000 312.00000 ? 75  LEU B CA    1 
ATOM   4435 C  C     . LEU B 2 75  ? 24.43800  7.31600   -9.31100  1.000 324.96000 ? 75  LEU B C     1 
ATOM   4436 O  O     . LEU B 2 75  ? 23.50300  6.51800   -9.44500  1.000 327.23000 ? 75  LEU B O     1 
ATOM   4437 C  CB    . LEU B 2 75  ? 24.04400  9.75900   -9.76800  1.000 314.30000 ? 75  LEU B CB    1 
ATOM   4438 C  CG    . LEU B 2 75  ? 23.55300  11.02200  -9.07300  1.000 313.15000 ? 75  LEU B CG    1 
ATOM   4439 C  CD1   . LEU B 2 75  ? 23.84000  12.20400  -9.97400  1.000 313.51000 ? 75  LEU B CD1   1 
ATOM   4440 C  CD2   . LEU B 2 75  ? 22.08600  10.90500  -8.72700  1.000 311.85000 ? 75  LEU B CD2   1 
ATOM   4441 N  N     . LYS B 2 76  ? 25.69700  7.01900   -9.67600  1.000 319.19000 ? 76  LYS B N     1 
ATOM   4442 C  CA    . LYS B 2 76  ? 26.04700  5.68000   -10.16500 1.000 318.35000 ? 76  LYS B CA    1 
ATOM   4443 C  C     . LYS B 2 76  ? 25.89400  4.63300   -9.06700  1.000 325.04000 ? 76  LYS B C     1 
ATOM   4444 O  O     . LYS B 2 76  ? 25.37500  3.53000   -9.31900  1.000 324.40000 ? 76  LYS B O     1 
ATOM   4445 C  CB    . LYS B 2 76  ? 27.49000  5.65700   -10.68700 1.000 316.61000 ? 76  LYS B CB    1 
ATOM   4446 C  CG    . LYS B 2 76  ? 27.71900  5.18700   -12.11500 1.000 308.21000 ? 76  LYS B CG    1 
ATOM   4447 C  CD    . LYS B 2 76  ? 27.67900  6.34500   -13.08200 1.000 312.52000 ? 76  LYS B CD    1 
ATOM   4448 C  CE    . LYS B 2 76  ? 26.51300  6.17900   -14.01300 1.000 307.05000 ? 76  LYS B CE    1 
ATOM   4449 N  NZ    . LYS B 2 76  ? 25.91000  7.49500   -14.31100 1.000 305.40000 ? 76  LYS B NZ    1 
ATOM   4450 N  N     . GLU B 2 77  ? 26.38400  4.95300   -7.85100  1.000 338.96000 ? 77  GLU B N     1 
ATOM   4451 C  CA    . GLU B 2 77  ? 26.11900  4.11100   -6.68800  1.000 336.19000 ? 77  GLU B CA    1 
ATOM   4452 C  C     . GLU B 2 77  ? 24.61400  3.92200   -6.49900  1.000 336.94000 ? 77  GLU B C     1 
ATOM   4453 O  O     . GLU B 2 77  ? 24.15700  2.79300   -6.26300  1.000 339.93000 ? 77  GLU B O     1 
ATOM   4454 C  CB    . GLU B 2 77  ? 26.77500  4.70000   -5.40900  1.000 328.03000 ? 77  GLU B CB    1 
ATOM   4455 C  CG    . GLU B 2 77  ? 28.23100  4.19200   -4.97600  1.000 318.12000 ? 77  GLU B CG    1 
ATOM   4456 C  CD    . GLU B 2 77  ? 28.78500  4.86400   -3.65400  1.000 318.83000 ? 77  GLU B CD    1 
ATOM   4457 O  OE1   . GLU B 2 77  ? 28.03300  5.14700   -2.71500  1.000 318.85000 ? 77  GLU B OE1   1 
ATOM   4458 O  OE2   . GLU B 2 77  ? 29.98900  5.06800   -3.54600  1.000 309.93000 ? 77  GLU B OE2   1 
ATOM   4459 N  N     . LEU B 2 78  ? 23.81500  4.99600   -6.64400  1.000 331.19000 ? 78  LEU B N     1 
ATOM   4460 C  CA    . LEU B 2 78  ? 22.37700  4.83900   -6.41700  1.000 325.14000 ? 78  LEU B CA    1 
ATOM   4461 C  C     . LEU B 2 78  ? 21.74500  3.90900   -7.44500  1.000 328.51000 ? 78  LEU B C     1 
ATOM   4462 O  O     . LEU B 2 78  ? 20.79800  3.17400   -7.11800  1.000 325.32000 ? 78  LEU B O     1 
ATOM   4463 C  CB    . LEU B 2 78  ? 21.67400  6.19300   -6.44100  1.000 317.55000 ? 78  LEU B CB    1 
ATOM   4464 C  CG    . LEU B 2 78  ? 20.62300  6.52800   -5.38100  1.000 313.94000 ? 78  LEU B CG    1 
ATOM   4465 C  CD1   . LEU B 2 78  ? 20.02300  7.89000   -5.73300  1.000 324.30000 ? 78  LEU B CD1   1 
ATOM   4466 C  CD2   . LEU B 2 78  ? 19.54300  5.44700   -5.22500  1.000 316.88000 ? 78  LEU B CD2   1 
ATOM   4467 N  N     . ALA B 2 79  ? 22.28300  3.91700   -8.68000  1.000 335.54000 ? 79  ALA B N     1 
ATOM   4468 C  CA    . ALA B 2 79  ? 21.73500  3.14300   -9.79700  1.000 333.36000 ? 79  ALA B CA    1 
ATOM   4469 C  C     . ALA B 2 79  ? 21.46500  1.69800   -9.44100  1.000 331.34000 ? 79  ALA B C     1 
ATOM   4470 O  O     . ALA B 2 79  ? 20.52500  1.08600   -9.95300  1.000 335.44000 ? 79  ALA B O     1 
ATOM   4471 C  CB    . ALA B 2 79  ? 22.70700  3.16400   -10.97700 1.000 320.30000 ? 79  ALA B CB    1 
ATOM   4472 N  N     . VAL B 2 80  ? 22.32000  1.11800   -8.61900  1.000 329.18000 ? 80  VAL B N     1 
ATOM   4473 C  CA    . VAL B 2 80  ? 22.18900  -0.29200  -8.30500  1.000 333.76000 ? 80  VAL B CA    1 
ATOM   4474 C  C     . VAL B 2 80  ? 21.06700  -0.53600  -7.29200  1.000 339.95000 ? 80  VAL B C     1 
ATOM   4475 O  O     . VAL B 2 80  ? 20.28300  -1.48200  -7.45200  1.000 345.46000 ? 80  VAL B O     1 
ATOM   4476 C  CB    . VAL B 2 80  ? 23.56100  -0.82200  -7.85000  1.000 335.26000 ? 80  VAL B CB    1 
ATOM   4477 C  CG1   . VAL B 2 80  ? 23.47200  -2.28400  -7.43100  1.000 344.76000 ? 80  VAL B CG1   1 
ATOM   4478 C  CG2   . VAL B 2 80  ? 24.60100  -0.57900  -8.95900  1.000 320.13000 ? 80  VAL B CG2   1 
ATOM   4479 N  N     . ALA B 2 81  ? 20.96100  0.29500   -6.24200  1.000 331.54000 ? 81  ALA B N     1 
ATOM   4480 C  CA    . ALA B 2 81  ? 19.99000  -0.00300  -5.19100  1.000 324.71000 ? 81  ALA B CA    1 
ATOM   4481 C  C     . ALA B 2 81  ? 18.58500  -0.08500  -5.74100  1.000 331.93000 ? 81  ALA B C     1 
ATOM   4482 O  O     . ALA B 2 81  ? 17.80000  -0.94500  -5.32500  1.000 335.51000 ? 81  ALA B O     1 
ATOM   4483 C  CB    . ALA B 2 81  ? 20.02900  1.05700   -4.09300  1.000 320.37000 ? 81  ALA B CB    1 
ATOM   4484 N  N     . THR B 2 82  ? 18.22800  0.85600   -6.61400  1.000 334.29000 ? 82  THR B N     1 
ATOM   4485 C  CA    . THR B 2 82  ? 16.94100  0.77300   -7.28100  1.000 341.48000 ? 82  THR B CA    1 
ATOM   4486 C  C     . THR B 2 82  ? 16.85300  -0.51200  -8.10100  1.000 348.72000 ? 82  THR B C     1 
ATOM   4487 O  O     . THR B 2 82  ? 15.87800  -1.27000  -7.97100  1.000 346.51000 ? 82  THR B O     1 
ATOM   4488 C  CB    . THR B 2 82  ? 16.70700  2.02500   -8.14500  1.000 346.35000 ? 82  THR B CB    1 
ATOM   4489 O  OG1   . THR B 2 82  ? 17.91300  2.41100   -8.81000  1.000 354.64000 ? 82  THR B OG1   1 
ATOM   4490 C  CG2   . THR B 2 82  ? 16.17900  3.20100   -7.31600  1.000 341.34000 ? 82  THR B CG2   1 
ATOM   4491 N  N     . LYS B 2 83  ? 17.88900  -0.78600  -8.92500  1.000 348.29000 ? 83  LYS B N     1 
ATOM   4492 C  CA    . LYS B 2 83  ? 17.99000  -2.05000  -9.66200  1.000 343.14000 ? 83  LYS B CA    1 
ATOM   4493 C  C     . LYS B 2 83  ? 17.79700  -3.21700  -8.71600  1.000 336.16000 ? 83  LYS B C     1 
ATOM   4494 O  O     . LYS B 2 83  ? 17.10900  -4.19800  -9.02800  1.000 329.77000 ? 83  LYS B O     1 
ATOM   4495 C  CB    . LYS B 2 83  ? 19.37200  -2.15600  -10.34900 1.000 335.12000 ? 83  LYS B CB    1 
ATOM   4496 C  CG    . LYS B 2 83  ? 19.42500  -2.21600  -11.91800 1.000 315.45000 ? 83  LYS B CG    1 
ATOM   4497 C  CD    . LYS B 2 83  ? 19.79600  -3.62600  -12.43300 1.000 328.44000 ? 83  LYS B CD    1 
ATOM   4498 C  CE    . LYS B 2 83  ? 19.50600  -3.79500  -13.91300 1.000 326.45000 ? 83  LYS B CE    1 
ATOM   4499 N  NZ    . LYS B 2 83  ? 18.11500  -4.28700  -14.08400 1.000 320.52000 ? 83  LYS B NZ    1 
ATOM   4500 N  N     . VAL B 2 84  ? 18.41800  -3.12800  -7.54400  1.000 339.09000 ? 84  VAL B N     1 
ATOM   4501 C  CA    . VAL B 2 84  ? 18.23000  -4.16100  -6.55400  1.000 330.22000 ? 84  VAL B CA    1 
ATOM   4502 C  C     . VAL B 2 84  ? 17.07600  -3.83500  -5.63600  1.000 330.14000 ? 84  VAL B C     1 
ATOM   4503 O  O     . VAL B 2 84  ? 16.66700  -4.69600  -4.85100  1.000 336.26000 ? 84  VAL B O     1 
ATOM   4504 C  CB    . VAL B 2 84  ? 19.57700  -4.36600  -5.83100  1.000 327.22000 ? 84  VAL B CB    1 
ATOM   4505 C  CG1   . VAL B 2 84  ? 19.53000  -5.56800  -4.89100  1.000 335.36000 ? 84  VAL B CG1   1 
ATOM   4506 C  CG2   . VAL B 2 84  ? 20.70400  -4.49500  -6.89200  1.000 334.81000 ? 84  VAL B CG2   1 
ATOM   4507 N  N     . LYS B 2 85  ? 16.48300  -2.64400  -5.75900  1.000 324.84000 ? 85  LYS B N     1 
ATOM   4508 C  CA    . LYS B 2 85  ? 15.28400  -2.35700  -4.98100  1.000 324.40000 ? 85  LYS B CA    1 
ATOM   4509 C  C     . LYS B 2 85  ? 14.19900  -3.36200  -5.28100  1.000 331.94000 ? 85  LYS B C     1 
ATOM   4510 O  O     . LYS B 2 85  ? 13.47500  -3.79600  -4.37800  1.000 335.00000 ? 85  LYS B O     1 
ATOM   4511 C  CB    . LYS B 2 85  ? 14.76200  -0.94700  -5.26700  1.000 325.21000 ? 85  LYS B CB    1 
ATOM   4512 C  CG    . LYS B 2 85  ? 13.93300  -0.43000  -4.13000  1.000 321.29000 ? 85  LYS B CG    1 
ATOM   4513 C  CD    . LYS B 2 85  ? 13.31800  0.92500   -4.39900  1.000 314.63000 ? 85  LYS B CD    1 
ATOM   4514 C  CE    . LYS B 2 85  ? 12.95900  1.59900   -3.06300  1.000 332.20000 ? 85  LYS B CE    1 
ATOM   4515 N  NZ    . LYS B 2 85  ? 12.30100  0.67900   -2.07300  1.000 336.95000 ? 85  LYS B NZ    1 
ATOM   4516 N  N     . LYS B 2 86  ? 14.05700  -3.73700  -6.54500  1.000 330.16000 ? 86  LYS B N     1 
ATOM   4517 C  CA    . LYS B 2 86  ? 13.00500  -4.68200  -6.87400  1.000 335.07000 ? 86  LYS B CA    1 
ATOM   4518 C  C     . LYS B 2 86  ? 13.36700  -6.08000  -6.41400  1.000 335.25000 ? 86  LYS B C     1 
ATOM   4519 O  O     . LYS B 2 86  ? 12.54200  -6.77500  -5.80600  1.000 340.17000 ? 86  LYS B O     1 
ATOM   4520 C  CB    . LYS B 2 86  ? 12.74600  -4.67000  -8.36700  1.000 340.86000 ? 86  LYS B CB    1 
ATOM   4521 C  CG    . LYS B 2 86  ? 11.85000  -5.78800  -8.84500  1.000 347.82000 ? 86  LYS B CG    1 
ATOM   4522 C  CD    . LYS B 2 86  ? 10.40100  -5.55000  -8.45000  1.000 351.50000 ? 86  LYS B CD    1 
ATOM   4523 C  CE    . LYS B 2 86  ? 9.49900   -5.96200  -9.60500  1.000 349.27000 ? 86  LYS B CE    1 
ATOM   4524 N  NZ    . LYS B 2 86  ? 8.10500   -5.45100  -9.52400  1.000 340.13000 ? 86  LYS B NZ    1 
ATOM   4525 N  N     . HIS B 2 87  ? 14.61200  -6.48900  -6.66900  1.000 322.93000 ? 87  HIS B N     1 
ATOM   4526 C  CA    . HIS B 2 87  ? 15.03800  -7.83600  -6.34300  1.000 324.70000 ? 87  HIS B CA    1 
ATOM   4527 C  C     . HIS B 2 87  ? 14.65600  -8.18700  -4.92000  1.000 329.11000 ? 87  HIS B C     1 
ATOM   4528 O  O     . HIS B 2 87  ? 14.05000  -9.24400  -4.68000  1.000 330.31000 ? 87  HIS B O     1 
ATOM   4529 C  CB    . HIS B 2 87  ? 16.53900  -7.96900  -6.55400  1.000 325.80000 ? 87  HIS B CB    1 
ATOM   4530 C  CG    . HIS B 2 87  ? 16.89300  -9.00300  -7.56800  1.000 322.72000 ? 87  HIS B CG    1 
ATOM   4531 N  ND1   . HIS B 2 87  ? 18.03300  -9.77200  -7.50300  1.000 330.66000 ? 87  HIS B ND1   1 
ATOM   4532 C  CD2   . HIS B 2 87  ? 16.24000  -9.39800  -8.68400  1.000 329.34000 ? 87  HIS B CD2   1 
ATOM   4533 C  CE1   . HIS B 2 87  ? 18.06900  -10.59200 -8.54000  1.000 341.50000 ? 87  HIS B CE1   1 
ATOM   4534 N  NE2   . HIS B 2 87  ? 16.99200  -10.38400 -9.27300  1.000 344.30000 ? 87  HIS B NE2   1 
ATOM   4535 N  N     . LEU B 2 88  ? 14.95700  -7.28600  -3.96100  1.000 338.79000 ? 88  LEU B N     1 
ATOM   4536 C  CA    . LEU B 2 88  ? 14.61000  -7.56500  -2.55900  1.000 340.15000 ? 88  LEU B CA    1 
ATOM   4537 C  C     . LEU B 2 88  ? 13.11300  -7.41500  -2.33100  1.000 332.23000 ? 88  LEU B C     1 
ATOM   4538 O  O     . LEU B 2 88  ? 12.53200  -8.07800  -1.46300  1.000 334.70000 ? 88  LEU B O     1 
ATOM   4539 C  CB    . LEU B 2 88  ? 15.40000  -6.65000  -1.58800  1.000 342.70000 ? 88  LEU B CB    1 
ATOM   4540 C  CG    . LEU B 2 88  ? 14.87100  -5.48200  -0.76100  1.000 341.98000 ? 88  LEU B CG    1 
ATOM   4541 C  CD1   . LEU B 2 88  ? 15.80600  -5.14900  0.43400   1.000 326.64000 ? 88  LEU B CD1   1 
ATOM   4542 C  CD2   . LEU B 2 88  ? 14.67400  -4.27700  -1.62900  1.000 326.58000 ? 88  LEU B CD2   1 
ATOM   4543 N  N     . GLN B 2 89  ? 12.49000  -6.52000  -3.08500  1.000 330.09000 ? 89  GLN B N     1 
ATOM   4544 C  CA    . GLN B 2 89  ? 11.05900  -6.25500  -2.99400  1.000 331.02000 ? 89  GLN B CA    1 
ATOM   4545 C  C     . GLN B 2 89  ? 10.64900  -5.86400  -1.57100  1.000 329.43000 ? 89  GLN B C     1 
ATOM   4546 O  O     . GLN B 2 89  ? 9.58800   -6.24300  -1.06700  1.000 329.25000 ? 89  GLN B O     1 
ATOM   4547 C  CB    . GLN B 2 89  ? 10.24100  -7.45200  -3.49500  1.000 331.52000 ? 89  GLN B CB    1 
ATOM   4548 C  CG    . GLN B 2 89  ? 9.15800   -7.08100  -4.50700  1.000 337.82000 ? 89  GLN B CG    1 
ATOM   4549 C  CD    . GLN B 2 89  ? 8.35300   -8.28000  -5.00200  1.000 340.90000 ? 89  GLN B CD    1 
ATOM   4550 O  OE1   . GLN B 2 89  ? 8.89300   -9.37100  -5.17000  1.000 346.37000 ? 89  GLN B OE1   1 
ATOM   4551 N  NE2   . GLN B 2 89  ? 7.05200   -8.07800  -5.23500  1.000 342.67000 ? 89  GLN B NE2   1 
ATOM   4552 N  N     . ASP B 2 90  ? 11.50800  -5.09700  -0.91700  1.000 337.75000 ? 90  ASP B N     1 
ATOM   4553 C  CA    . ASP B 2 90  ? 11.22500  -4.43700  0.35300   1.000 340.33000 ? 90  ASP B CA    1 
ATOM   4554 C  C     . ASP B 2 90  ? 11.32100  -2.93400  0.16100   1.000 337.90000 ? 90  ASP B C     1 
ATOM   4555 O  O     . ASP B 2 90  ? 12.34200  -2.43000  -0.33300  1.000 332.79000 ? 90  ASP B O     1 
ATOM   4556 C  CB    . ASP B 2 90  ? 12.21100  -4.88700  1.42400   1.000 349.94000 ? 90  ASP B CB    1 
ATOM   4557 C  CG    . ASP B 2 90  ? 12.41700  -3.89400  2.54700   1.000 353.63000 ? 90  ASP B CG    1 
ATOM   4558 O  OD1   . ASP B 2 90  ? 11.50700  -3.09200  2.87400   1.000 357.71000 ? 90  ASP B OD1   1 
ATOM   4559 O  OD2   . ASP B 2 90  ? 13.52100  -3.95500  3.15600   1.000 354.30000 ? 90  ASP B OD2   1 
ATOM   4560 N  N     . ASP B 2 91  ? 10.27600  -2.22400  0.61000   1.000 339.15000 ? 91  ASP B N     1 
ATOM   4561 C  CA    . ASP B 2 91  ? 10.11500  -0.80400  0.29400   1.000 335.01000 ? 91  ASP B CA    1 
ATOM   4562 C  C     . ASP B 2 91  ? 11.19600  0.07800   0.93300   1.000 332.32000 ? 91  ASP B C     1 
ATOM   4563 O  O     . ASP B 2 91  ? 11.63400  1.06500   0.32300   1.000 324.27000 ? 91  ASP B O     1 
ATOM   4564 C  CB    . ASP B 2 91  ? 8.71200   -0.36900  0.73600   1.000 336.38000 ? 91  ASP B CB    1 
ATOM   4565 C  CG    . ASP B 2 91  ? 7.64600   -1.43700  0.42500   1.000 344.13000 ? 91  ASP B CG    1 
ATOM   4566 O  OD1   . ASP B 2 91  ? 7.46800   -1.76600  -0.77000  1.000 349.11000 ? 91  ASP B OD1   1 
ATOM   4567 O  OD2   . ASP B 2 91  ? 6.98400   -1.96800  1.35400   1.000 340.11000 ? 91  ASP B OD2   1 
ATOM   4568 N  N     . MET B 2 92  ? 11.62800  -0.24700  2.16200   1.000 338.47000 ? 92  MET B N     1 
ATOM   4569 C  CA    . MET B 2 92  ? 12.60900  0.55300   2.90000   1.000 331.62000 ? 92  MET B CA    1 
ATOM   4570 C  C     . MET B 2 92  ? 14.07600  0.20600   2.57200   1.000 327.65000 ? 92  MET B C     1 
ATOM   4571 O  O     . MET B 2 92  ? 14.95700  0.54500   3.38100   1.000 321.97000 ? 92  MET B O     1 
ATOM   4572 C  CB    . MET B 2 92  ? 12.41700  0.41400   4.43400   1.000 326.97000 ? 92  MET B CB    1 
ATOM   4573 C  CG    . MET B 2 92  ? 11.24000  1.18400   5.09900   1.000 319.65000 ? 92  MET B CG    1 
ATOM   4574 S  SD    . MET B 2 92  ? 9.60100   0.43400   4.76300   1.000 345.67000 ? 92  MET B SD    1 
ATOM   4575 C  CE    . MET B 2 92  ? 8.54500   0.84100   6.16800   1.000 332.62000 ? 92  MET B CE    1 
ATOM   4576 N  N     . PHE B 2 93  ? 14.36600  -0.45000  1.43400   1.000 340.88000 ? 93  PHE B N     1 
ATOM   4577 C  CA    . PHE B 2 93  ? 15.75600  -0.82300  1.15000   1.000 334.83000 ? 93  PHE B CA    1 
ATOM   4578 C  C     . PHE B 2 93  ? 16.67000  0.39400   1.07800   1.000 335.16000 ? 93  PHE B C     1 
ATOM   4579 O  O     . PHE B 2 93  ? 17.81400  0.34800   1.55300   1.000 334.97000 ? 93  PHE B O     1 
ATOM   4580 C  CB    . PHE B 2 93  ? 15.86000  -1.58700  -0.16300  1.000 321.07000 ? 93  PHE B CB    1 
ATOM   4581 C  CG    . PHE B 2 93  ? 17.29500  -1.98200  -0.55700  1.000 316.94000 ? 93  PHE B CG    1 
ATOM   4582 C  CD1   . PHE B 2 93  ? 17.89600  -1.44800  -1.68600  1.000 320.40000 ? 93  PHE B CD1   1 
ATOM   4583 C  CD2   . PHE B 2 93  ? 18.02000  -2.90000  0.17300   1.000 314.43000 ? 93  PHE B CD2   1 
ATOM   4584 C  CE1   . PHE B 2 93  ? 19.18300  -1.82000  -2.06000  1.000 317.19000 ? 93  PHE B CE1   1 
ATOM   4585 C  CE2   . PHE B 2 93  ? 19.30100  -3.28200  -0.20100  1.000 317.83000 ? 93  PHE B CE2   1 
ATOM   4586 C  CZ    . PHE B 2 93  ? 19.88600  -2.73700  -1.31400  1.000 314.18000 ? 93  PHE B CZ    1 
ATOM   4587 N  N     . ILE B 2 94  ? 16.21100  1.46800   0.42700   1.000 340.93000 ? 94  ILE B N     1 
ATOM   4588 C  CA    . ILE B 2 94  ? 16.98900  2.69400   0.26000   1.000 335.86000 ? 94  ILE B CA    1 
ATOM   4589 C  C     . ILE B 2 94  ? 16.51200  3.68900   1.30100   1.000 323.28000 ? 94  ILE B C     1 
ATOM   4590 O  O     . ILE B 2 94  ? 15.30500  3.85000   1.53100   1.000 322.14000 ? 94  ILE B O     1 
ATOM   4591 C  CB    . ILE B 2 94  ? 16.90000  3.33400   -1.14800  1.000 344.32000 ? 94  ILE B CB    1 
ATOM   4592 C  CG1   . ILE B 2 94  ? 17.21400  2.32200   -2.27900  1.000 341.08000 ? 94  ILE B CG1   1 
ATOM   4593 C  CG2   . ILE B 2 94  ? 17.87100  4.52300   -1.23300  1.000 329.55000 ? 94  ILE B CG2   1 
ATOM   4594 C  CD1   . ILE B 2 94  ? 17.17000  2.88800   -3.75700  1.000 332.17000 ? 94  ILE B CD1   1 
ATOM   4595 N  N     . ILE B 2 95  ? 17.46900  4.34800   1.93400   1.000 314.72000 ? 95  ILE B N     1 
ATOM   4596 C  CA    . ILE B 2 95  ? 17.16600  5.32600   2.95800   1.000 313.00000 ? 95  ILE B CA    1 
ATOM   4597 C  C     . ILE B 2 95  ? 17.93400  6.58800   2.61800   1.000 314.70000 ? 95  ILE B C     1 
ATOM   4598 O  O     . ILE B 2 95  ? 19.17300  6.59700   2.67200   1.000 310.78000 ? 95  ILE B O     1 
ATOM   4599 C  CB    . ILE B 2 95  ? 17.51800  4.77900   4.34000   1.000 306.51000 ? 95  ILE B CB    1 
ATOM   4600 C  CG1   . ILE B 2 95  ? 16.66000  3.54100   4.59100   1.000 305.06000 ? 95  ILE B CG1   1 
ATOM   4601 C  CG2   . ILE B 2 95  ? 17.29200  5.83600   5.41300   1.000 305.87000 ? 95  ILE B CG2   1 
ATOM   4602 C  CD1   . ILE B 2 95  ? 17.17000  2.62800   5.64800   1.000 303.54000 ? 95  ILE B CD1   1 
ATOM   4603 N  N     . PRO B 2 96  ? 17.24400  7.63900   2.18400   1.000 310.93000 ? 96  PRO B N     1 
ATOM   4604 C  CA    . PRO B 2 96  ? 17.91900  8.91700   2.00300   1.000 305.04000 ? 96  PRO B CA    1 
ATOM   4605 C  C     . PRO B 2 96  ? 18.24500  9.40400   3.38800   1.000 305.43000 ? 96  PRO B C     1 
ATOM   4606 O  O     . PRO B 2 96  ? 17.40300  9.35600   4.29200   1.000 304.84000 ? 96  PRO B O     1 
ATOM   4607 C  CB    . PRO B 2 96  ? 16.85900  9.80300   1.37200   1.000 320.53000 ? 96  PRO B CB    1 
ATOM   4608 C  CG    . PRO B 2 96  ? 15.59500  9.25700   1.93300   1.000 327.07000 ? 96  PRO B CG    1 
ATOM   4609 C  CD    . PRO B 2 96  ? 15.78100  7.78000   2.11100   1.000 317.53000 ? 96  PRO B CD    1 
ATOM   4610 N  N     . LEU B 2 97  ? 19.45400  9.87200   3.55500   1.000 310.73000 ? 97  LEU B N     1 
ATOM   4611 C  CA    . LEU B 2 97  ? 19.88300  10.38600  4.83700   1.000 315.47000 ? 97  LEU B CA    1 
ATOM   4612 C  C     . LEU B 2 97  ? 19.89600  11.90000  4.67500   1.000 323.50000 ? 97  LEU B C     1 
ATOM   4613 O  O     . LEU B 2 97  ? 20.81300  12.46600  4.07400   1.000 328.70000 ? 97  LEU B O     1 
ATOM   4614 C  CB    . LEU B 2 97  ? 21.22100  9.78300   5.23200   1.000 319.57000 ? 97  LEU B CB    1 
ATOM   4615 C  CG    . LEU B 2 97  ? 21.31000  8.23900   5.19700   1.000 318.80000 ? 97  LEU B CG    1 
ATOM   4616 C  CD1   . LEU B 2 97  ? 22.73900  7.79400   5.38100   1.000 314.40000 ? 97  LEU B CD1   1 
ATOM   4617 C  CD2   . LEU B 2 97  ? 20.44800  7.57400   6.26000   1.000 317.30000 ? 97  LEU B CD2   1 
ATOM   4618 N  N     . ALA B 2 98  ? 18.82400  12.55600  5.13400   1.000 322.45000 ? 98  ALA B N     1 
ATOM   4619 C  CA    . ALA B 2 98  ? 18.67600  14.00300  4.94100   1.000 322.84000 ? 98  ALA B CA    1 
ATOM   4620 C  C     . ALA B 2 98  ? 19.44200  14.74200  6.03300   1.000 323.26000 ? 98  ALA B C     1 
ATOM   4621 O  O     . ALA B 2 98  ? 18.90900  15.06900  7.09500   1.000 319.51000 ? 98  ALA B O     1 
ATOM   4622 C  CB    . ALA B 2 98  ? 17.20900  14.41000  4.91100   1.000 318.32000 ? 98  ALA B CB    1 
ATOM   4623 N  N     . ILE B 2 99  ? 20.71500  15.02300  5.72800   1.000 325.74000 ? 99  ILE B N     1 
ATOM   4624 C  CA    . ILE B 2 99  ? 21.63600  15.78300  6.57200   1.000 327.97000 ? 99  ILE B CA    1 
ATOM   4625 C  C     . ILE B 2 99  ? 21.69300  17.25500  6.17200   1.000 325.99000 ? 99  ILE B C     1 
ATOM   4626 O  O     . ILE B 2 99  ? 22.20400  18.08200  6.94700   1.000 330.97000 ? 99  ILE B O     1 
ATOM   4627 C  CB    . ILE B 2 99  ? 23.08200  15.19900  6.54600   1.000 327.81000 ? 99  ILE B CB    1 
ATOM   4628 C  CG1   . ILE B 2 99  ? 23.79000  15.53800  5.20800   1.000 325.56000 ? 99  ILE B CG1   1 
ATOM   4629 C  CG2   . ILE B 2 99  ? 23.12400  13.66700  6.84400   1.000 323.16000 ? 99  ILE B CG2   1 
ATOM   4630 C  CD1   . ILE B 2 99  ? 25.33200  15.36500  5.21700   1.000 311.99000 ? 99  ILE B CD1   1 
ATOM   4631 N  N     . ASP B 2 100 ? 21.18100  17.61200  4.99100   1.000 315.30000 ? 100 ASP B N     1 
ATOM   4632 C  CA    . ASP B 2 100 ? 21.31200  18.95800  4.44400   1.000 314.48000 ? 100 ASP B CA    1 
ATOM   4633 C  C     . ASP B 2 100 ? 20.11800  19.80500  4.85700   1.000 321.06000 ? 100 ASP B C     1 
ATOM   4634 O  O     . ASP B 2 100 ? 18.97300  19.45800  4.54000   1.000 316.20000 ? 100 ASP B O     1 
ATOM   4635 C  CB    . ASP B 2 100 ? 21.44800  18.90700  2.92400   1.000 313.64000 ? 100 ASP B CB    1 
ATOM   4636 C  CG    . ASP B 2 100 ? 22.15100  20.12700  2.36800   1.000 311.17000 ? 100 ASP B CG    1 
ATOM   4637 O  OD1   . ASP B 2 100 ? 22.32000  21.12200  3.10300   1.000 320.05000 ? 100 ASP B OD1   1 
ATOM   4638 O  OD2   . ASP B 2 100 ? 22.55000  20.08500  1.19200   1.000 310.12000 ? 100 ASP B OD2   1 
ATOM   4639 N  N     . GLU B 2 101 ? 20.39900  20.89500  5.59700   1.000 325.45000 ? 101 GLU B N     1 
ATOM   4640 C  CA    . GLU B 2 101 ? 19.37500  21.88200  5.92100   1.000 324.46000 ? 101 GLU B CA    1 
ATOM   4641 C  C     . GLU B 2 101 ? 18.82000  22.57100  4.68200   1.000 334.31000 ? 101 GLU B C     1 
ATOM   4642 O  O     . GLU B 2 101 ? 17.74200  23.17400  4.76500   1.000 340.05000 ? 101 GLU B O     1 
ATOM   4643 C  CB    . GLU B 2 101 ? 19.89600  23.00000  6.82800   1.000 320.09000 ? 101 GLU B CB    1 
ATOM   4644 C  CG    . GLU B 2 101 ? 20.06700  22.66600  8.28000   1.000 331.80000 ? 101 GLU B CG    1 
ATOM   4645 C  CD    . GLU B 2 101 ? 21.41100  22.04400  8.53700   1.000 331.51000 ? 101 GLU B CD    1 
ATOM   4646 O  OE1   . GLU B 2 101 ? 21.46800  21.02200  9.25500   1.000 334.40000 ? 101 GLU B OE1   1 
ATOM   4647 O  OE2   . GLU B 2 101 ? 22.40900  22.57700  7.99900   1.000 336.64000 ? 101 GLU B OE2   1 
ATOM   4648 N  N     . ASN B 2 102 ? 19.53200  22.52400  3.53500   1.000 338.44000 ? 102 ASN B N     1 
ATOM   4649 C  CA    . ASN B 2 102 ? 19.16400  23.29900  2.33800   1.000 328.27000 ? 102 ASN B CA    1 
ATOM   4650 C  C     . ASN B 2 102 ? 19.09800  22.38700  1.10900   1.000 324.66000 ? 102 ASN B C     1 
ATOM   4651 O  O     . ASN B 2 102 ? 19.86300  22.58000  0.15900   1.000 322.26000 ? 102 ASN B O     1 
ATOM   4652 C  CB    . ASN B 2 102 ? 20.13400  24.43900  2.10200   1.000 321.26000 ? 102 ASN B CB    1 
ATOM   4653 C  CG    . ASN B 2 102 ? 19.99100  25.54400  3.12300   1.000 327.71000 ? 102 ASN B CG    1 
ATOM   4654 O  OD1   . ASN B 2 102 ? 18.88800  25.94300  3.49000   1.000 335.77000 ? 102 ASN B OD1   1 
ATOM   4655 N  ND2   . ASN B 2 102 ? 21.12000  26.04600  3.59100   1.000 329.92000 ? 102 ASN B ND2   1 
ATOM   4656 N  N     . LEU B 2 103 ? 18.13700  21.45800  1.10900   1.000 327.34000 ? 103 LEU B N     1 
ATOM   4657 C  CA    . LEU B 2 103 ? 17.78400  20.66700  -0.06700  1.000 333.95000 ? 103 LEU B CA    1 
ATOM   4658 C  C     . LEU B 2 103 ? 16.49100  21.20500  -0.67300  1.000 335.17000 ? 103 LEU B C     1 
ATOM   4659 O  O     . LEU B 2 103 ? 15.40900  21.05500  -0.09100  1.000 339.14000 ? 103 LEU B O     1 
ATOM   4660 C  CB    . LEU B 2 103 ? 17.64800  19.17500  0.26900   1.000 333.39000 ? 103 LEU B CB    1 
ATOM   4661 C  CG    . LEU B 2 103 ? 18.62900  18.34600  -0.55100  1.000 327.28000 ? 103 LEU B CG    1 
ATOM   4662 C  CD1   . LEU B 2 103 ? 20.00800  18.99900  -0.52300  1.000 317.77000 ? 103 LEU B CD1   1 
ATOM   4663 C  CD2   . LEU B 2 103 ? 18.63100  16.77500  -0.22600  1.000 322.82000 ? 103 LEU B CD2   1 
ATOM   4664 N  N     . SER B 2 104 ? 16.60800  21.82900  -1.84100  1.000 340.17000 ? 104 SER B N     1 
ATOM   4665 C  CA    . SER B 2 104 ? 15.43500  22.03100  -2.67300  1.000 341.33000 ? 104 SER B CA    1 
ATOM   4666 C  C     . SER B 2 104 ? 14.96900  20.70500  -3.25800  1.000 340.53000 ? 104 SER B C     1 
ATOM   4667 O  O     . SER B 2 104 ? 15.77000  19.80900  -3.57600  1.000 345.07000 ? 104 SER B O     1 
ATOM   4668 C  CB    . SER B 2 104 ? 15.70600  23.01100  -3.82200  1.000 345.56000 ? 104 SER B CB    1 
ATOM   4669 O  OG    . SER B 2 104 ? 16.97900  23.62100  -3.69700  1.000 347.59000 ? 104 SER B OG    1 
ATOM   4670 N  N     . TYR B 2 105 ? 13.64200  20.60100  -3.37700  1.000 325.55000 ? 105 TYR B N     1 
ATOM   4671 C  CA    . TYR B 2 105 ? 12.99900  19.44900  -3.99400  1.000 319.48000 ? 105 TYR B CA    1 
ATOM   4672 C  C     . TYR B 2 105 ? 13.65600  19.09900  -5.31800  1.000 318.67000 ? 105 TYR B C     1 
ATOM   4673 O  O     . TYR B 2 105 ? 13.83000  17.91300  -5.64700  1.000 315.50000 ? 105 TYR B O     1 
ATOM   4674 C  CB    . TYR B 2 105 ? 11.52600  19.79500  -4.20900  1.000 319.27000 ? 105 TYR B CB    1 
ATOM   4675 C  CG    . TYR B 2 105 ? 10.62200  18.64700  -4.34600  1.000 317.17000 ? 105 TYR B CG    1 
ATOM   4676 C  CD1   . TYR B 2 105 ? 10.87000  17.69400  -5.27600  1.000 317.28000 ? 105 TYR B CD1   1 
ATOM   4677 C  CD2   . TYR B 2 105 ? 9.48300   18.52500  -3.54500  1.000 323.10000 ? 105 TYR B CD2   1 
ATOM   4678 C  CE1   . TYR B 2 105 ? 10.02200  16.64900  -5.39000  1.000 323.72000 ? 105 TYR B CE1   1 
ATOM   4679 C  CE2   . TYR B 2 105 ? 8.63900   17.45800  -3.67300  1.000 330.67000 ? 105 TYR B CE2   1 
ATOM   4680 C  CZ    . TYR B 2 105 ? 8.92500   16.52000  -4.59100  1.000 328.18000 ? 105 TYR B CZ    1 
ATOM   4681 O  OH    . TYR B 2 105 ? 8.06200   15.45100  -4.74600  1.000 319.98000 ? 105 TYR B OH    1 
ATOM   4682 N  N     . ASP B 2 106 ? 13.99200  20.14100  -6.09800  1.000 333.62000 ? 106 ASP B N     1 
ATOM   4683 C  CA    . ASP B 2 106 ? 14.51700  19.98000  -7.45500  1.000 339.40000 ? 106 ASP B CA    1 
ATOM   4684 C  C     . ASP B 2 106 ? 15.85400  19.24400  -7.47600  1.000 345.43000 ? 106 ASP B C     1 
ATOM   4685 O  O     . ASP B 2 106 ? 16.12800  18.45600  -8.39600  1.000 341.31000 ? 106 ASP B O     1 
ATOM   4686 C  CB    . ASP B 2 106 ? 14.68300  21.35500  -8.09800  1.000 343.44000 ? 106 ASP B CB    1 
ATOM   4687 C  CG    . ASP B 2 106 ? 14.07700  21.44200  -9.48300  1.000 343.81000 ? 106 ASP B CG    1 
ATOM   4688 O  OD1   . ASP B 2 106 ? 14.57100  22.26600  -10.28300 1.000 347.65000 ? 106 ASP B OD1   1 
ATOM   4689 O  OD2   . ASP B 2 106 ? 13.12800  20.69500  -9.78000  1.000 341.54000 ? 106 ASP B OD2   1 
ATOM   4690 N  N     . ASP B 2 107 ? 16.73200  19.53100  -6.50900  1.000 348.66000 ? 107 ASP B N     1 
ATOM   4691 C  CA    . ASP B 2 107 ? 17.99500  18.79100  -6.46400  1.000 349.54000 ? 107 ASP B CA    1 
ATOM   4692 C  C     . ASP B 2 107 ? 17.75500  17.30600  -6.21900  1.000 351.10000 ? 107 ASP B C     1 
ATOM   4693 O  O     . ASP B 2 107 ? 18.33100  16.46400  -6.92200  1.000 350.81000 ? 107 ASP B O     1 
ATOM   4694 C  CB    . ASP B 2 107 ? 18.95900  19.31800  -5.38800  1.000 347.70000 ? 107 ASP B CB    1 
ATOM   4695 C  CG    . ASP B 2 107 ? 18.85900  20.83600  -5.14600  1.000 347.58000 ? 107 ASP B CG    1 
ATOM   4696 O  OD1   . ASP B 2 107 ? 18.29800  21.22900  -4.10100  1.000 350.31000 ? 107 ASP B OD1   1 
ATOM   4697 O  OD2   . ASP B 2 107 ? 19.36700  21.63400  -5.96000  1.000 346.89000 ? 107 ASP B OD2   1 
ATOM   4698 N  N     . ILE B 2 108 ? 16.89800  16.96700  -5.23700  1.000 349.55000 ? 108 ILE B N     1 
ATOM   4699 C  CA    . ILE B 2 108 ? 16.77000  15.57800  -4.80200  1.000 348.39000 ? 108 ILE B CA    1 
ATOM   4700 C  C     . ILE B 2 108 ? 16.42900  14.71100  -6.01000  1.000 357.69000 ? 108 ILE B C     1 
ATOM   4701 O  O     . ILE B 2 108 ? 15.59600  15.08300  -6.85300  1.000 352.54000 ? 108 ILE B O     1 
ATOM   4702 C  CB    . ILE B 2 108 ? 15.71000  15.38000  -3.70200  1.000 335.52000 ? 108 ILE B CB    1 
ATOM   4703 C  CG1   . ILE B 2 108 ? 15.73400  16.49300  -2.66200  1.000 334.20000 ? 108 ILE B CG1   1 
ATOM   4704 C  CG2   . ILE B 2 108 ? 15.84300  13.94000  -3.13000  1.000 331.58000 ? 108 ILE B CG2   1 
ATOM   4705 C  CD1   . ILE B 2 108 ? 15.01100  16.14600  -1.35400  1.000 332.99000 ? 108 ILE B CD1   1 
ATOM   4706 N  N     . ASN B 2 109 ? 17.10000  13.55900  -6.11700  1.000 359.02000 ? 109 ASN B N     1 
ATOM   4707 C  CA    . ASN B 2 109 ? 16.84500  12.64300  -7.22500  1.000 357.15000 ? 109 ASN B CA    1 
ATOM   4708 C  C     . ASN B 2 109 ? 15.49100  11.96800  -7.05300  1.000 354.20000 ? 109 ASN B C     1 
ATOM   4709 O  O     . ASN B 2 109 ? 15.08700  11.59700  -5.94400  1.000 353.93000 ? 109 ASN B O     1 
ATOM   4710 C  CB    . ASN B 2 109 ? 17.95700  11.58500  -7.32600  1.000 351.42000 ? 109 ASN B CB    1 
ATOM   4711 C  CG    . ASN B 2 109 ? 17.83800  10.70800  -8.58500  1.000 335.53000 ? 109 ASN B CG    1 
ATOM   4712 O  OD1   . ASN B 2 109 ? 17.33300  9.58000   -8.53500  1.000 336.77000 ? 109 ASN B OD1   1 
ATOM   4713 N  ND2   . ASN B 2 109 ? 18.32500  11.21600  -9.70500  1.000 325.54000 ? 109 ASN B ND2   1 
ATOM   4714 N  N     . ILE B 2 110 ? 14.81500  11.79000  -8.18500  1.000 350.25000 ? 110 ILE B N     1 
ATOM   4715 C  CA    . ILE B 2 110 ? 13.40100  11.43400  -8.20600  1.000 352.22000 ? 110 ILE B CA    1 
ATOM   4716 C  C     . ILE B 2 110 ? 13.14900  10.16100  -7.40700  1.000 349.06000 ? 110 ILE B C     1 
ATOM   4717 O  O     . ILE B 2 110 ? 12.28800  10.12900  -6.51200  1.000 339.79000 ? 110 ILE B O     1 
ATOM   4718 C  CB    . ILE B 2 110 ? 12.94800  11.31600  -9.67500  1.000 351.40000 ? 110 ILE B CB    1 
ATOM   4719 C  CG1   . ILE B 2 110 ? 11.59100  10.62200  -9.81100  1.000 361.29000 ? 110 ILE B CG1   1 
ATOM   4720 C  CG2   . ILE B 2 110 ? 14.08100  10.69500  -10.54100 1.000 336.48000 ? 110 ILE B CG2   1 
ATOM   4721 C  CD1   . ILE B 2 110 ? 10.54400  11.50100  -10.53200 1.000 354.54000 ? 110 ILE B CD1   1 
ATOM   4722 N  N     . GLU B 2 111 ? 13.95000  9.12300   -7.66300  1.000 341.65000 ? 111 GLU B N     1 
ATOM   4723 C  CA    . GLU B 2 111 ? 13.79000  7.85400   -6.96800  1.000 337.38000 ? 111 GLU B CA    1 
ATOM   4724 C  C     . GLU B 2 111 ? 13.67500  8.08500   -5.48000  1.000 338.30000 ? 111 GLU B C     1 
ATOM   4725 O  O     . GLU B 2 111 ? 12.71500  7.64100   -4.82900  1.000 340.72000 ? 111 GLU B O     1 
ATOM   4726 C  CB    . GLU B 2 111 ? 14.98900  6.95900   -7.25200  1.000 342.35000 ? 111 GLU B CB    1 
ATOM   4727 C  CG    . GLU B 2 111 ? 15.31700  6.74200   -8.72400  1.000 335.37000 ? 111 GLU B CG    1 
ATOM   4728 C  CD    . GLU B 2 111 ? 14.41200  5.71200   -9.35400  1.000 340.15000 ? 111 GLU B CD    1 
ATOM   4729 O  OE1   . GLU B 2 111 ? 14.36900  5.63500   -10.59900 1.000 338.01000 ? 111 GLU B OE1   1 
ATOM   4730 O  OE2   . GLU B 2 111 ? 13.73500  4.98200   -8.59900  1.000 339.65000 ? 111 GLU B OE2   1 
ATOM   4731 N  N     . ILE B 2 112 ? 14.64800  8.82200   -4.93200  1.000 339.06000 ? 112 ILE B N     1 
ATOM   4732 C  CA    . ILE B 2 112 ? 14.65600  9.10500   -3.50000  1.000 342.59000 ? 112 ILE B CA    1 
ATOM   4733 C  C     . ILE B 2 112 ? 13.83900  10.33100  -3.11100  1.000 339.39000 ? 112 ILE B C     1 
ATOM   4734 O  O     . ILE B 2 112 ? 13.57900  10.51600  -1.91600  1.000 348.80000 ? 112 ILE B O     1 
ATOM   4735 C  CB    . ILE B 2 112 ? 16.11200  9.18800   -2.95200  1.000 350.60000 ? 112 ILE B CB    1 
ATOM   4736 C  CG1   . ILE B 2 112 ? 16.78300  10.56900  -3.15000  1.000 341.97000 ? 112 ILE B CG1   1 
ATOM   4737 C  CG2   . ILE B 2 112 ? 16.99000  8.06700   -3.54200  1.000 345.88000 ? 112 ILE B CG2   1 
ATOM   4738 C  CD1   . ILE B 2 112 ? 18.24800  10.66000  -2.60600  1.000 331.27000 ? 112 ILE B CD1   1 
ATOM   4739 N  N     . VAL B 2 113 ? 13.40200  11.16600  -4.04600  1.000 337.52000 ? 113 VAL B N     1 
ATOM   4740 C  CA    . VAL B 2 113 ? 12.45000  12.15800  -3.59400  1.000 332.44000 ? 113 VAL B CA    1 
ATOM   4741 C  C     . VAL B 2 113 ? 11.30500  11.44200  -2.91100  1.000 334.77000 ? 113 VAL B C     1 
ATOM   4742 O  O     . VAL B 2 113 ? 10.92300  11.79400  -1.79200  1.000 343.21000 ? 113 VAL B O     1 
ATOM   4743 C  CB    . VAL B 2 113 ? 11.97600  13.02500  -4.76200  1.000 326.88000 ? 113 VAL B CB    1 
ATOM   4744 C  CG1   . VAL B 2 113 ? 10.80100  13.92400  -4.29600  1.000 328.98000 ? 113 VAL B CG1   1 
ATOM   4745 C  CG2   . VAL B 2 113 ? 13.16700  13.77800  -5.31500  1.000 328.46000 ? 113 VAL B CG2   1 
ATOM   4746 N  N     . ARG B 2 114 ? 10.84000  10.33400  -3.50400  1.000 319.93000 ? 114 ARG B N     1 
ATOM   4747 C  CA    . ARG B 2 114 ? 9.60200   9.71900   -3.03300  1.000 326.91000 ? 114 ARG B CA    1 
ATOM   4748 C  C     . ARG B 2 114 ? 9.68000   9.29700   -1.57500  1.000 332.05000 ? 114 ARG B C     1 
ATOM   4749 O  O     . ARG B 2 114 ? 8.69100   9.38500   -0.85300  1.000 342.11000 ? 114 ARG B O     1 
ATOM   4750 C  CB    . ARG B 2 114 ? 9.23700   8.51700   -3.91000  1.000 325.20000 ? 114 ARG B CB    1 
ATOM   4751 N  N     . LEU B 2 115 ? 10.82700  8.82400   -1.13100  1.000 323.81000 ? 115 LEU B N     1 
ATOM   4752 C  CA    . LEU B 2 115 ? 10.89900  8.02900   0.07800   1.000 320.57000 ? 115 LEU B CA    1 
ATOM   4753 C  C     . LEU B 2 115 ? 10.77100  8.91000   1.32700   1.000 326.35000 ? 115 LEU B C     1 
ATOM   4754 O  O     . LEU B 2 115 ? 10.61800  10.13700  1.24900   1.000 331.77000 ? 115 LEU B O     1 
ATOM   4755 C  CB    . LEU B 2 115 ? 12.21100  7.25100   0.04900   1.000 320.63000 ? 115 LEU B CB    1 
ATOM   4756 C  CG    . LEU B 2 115 ? 12.19900  6.30500   -1.13800  1.000 326.28000 ? 115 LEU B CG    1 
ATOM   4757 C  CD1   . LEU B 2 115 ? 13.59400  6.01700   -1.66400  1.000 322.73000 ? 115 LEU B CD1   1 
ATOM   4758 C  CD2   . LEU B 2 115 ? 11.51200  5.02400   -0.69600  1.000 317.86000 ? 115 LEU B CD2   1 
ATOM   4759 N  N     . ASN B 2 116 ? 10.82800  8.25200   2.48700   1.000 332.26000 ? 116 ASN B N     1 
ATOM   4760 C  CA    . ASN B 2 116 ? 10.60600  8.87100   3.79300   1.000 336.37000 ? 116 ASN B CA    1 
ATOM   4761 C  C     . ASN B 2 116 ? 11.89700  9.48800   4.33500   1.000 341.67000 ? 116 ASN B C     1 
ATOM   4762 O  O     . ASN B 2 116 ? 13.00400  9.03600   4.02400   1.000 343.10000 ? 116 ASN B O     1 
ATOM   4763 C  CB    . ASN B 2 116 ? 10.07400  7.80800   4.76600   1.000 332.91000 ? 116 ASN B CB    1 
ATOM   4764 C  CG    . ASN B 2 116 ? 9.43100   8.39500   6.03200   1.000 331.91000 ? 116 ASN B CG    1 
ATOM   4765 O  OD1   . ASN B 2 116 ? 9.19500   9.59900   6.13700   1.000 323.04000 ? 116 ASN B OD1   1 
ATOM   4766 N  ND2   . ASN B 2 116 ? 9.13000   7.53100   6.98800   1.000 341.70000 ? 116 ASN B ND2   1 
ATOM   4767 N  N     . ALA B 2 117 ? 11.74900  10.53500  5.16000   1.000 354.96000 ? 117 ALA B N     1 
ATOM   4768 C  CA    . ALA B 2 117 ? 12.87300  11.39700  5.55700   1.000 348.65000 ? 117 ALA B CA    1 
ATOM   4769 C  C     . ALA B 2 117 ? 13.50000  10.91100  6.87400   1.000 333.03000 ? 117 ALA B C     1 
ATOM   4770 O  O     . ALA B 2 117 ? 12.81900  10.83800  7.90700   1.000 329.85000 ? 117 ALA B O     1 
ATOM   4771 C  CB    . ALA B 2 117 ? 12.41600  12.86300  5.67500   1.000 343.39000 ? 117 ALA B CB    1 
ATOM   4772 N  N     . ILE B 2 118 ? 14.79200  10.56000  6.82800   1.000 325.29000 ? 118 ILE B N     1 
ATOM   4773 C  CA    . ILE B 2 118 ? 15.58400  10.25900  8.02000   1.000 307.24000 ? 118 ILE B CA    1 
ATOM   4774 C  C     . ILE B 2 118 ? 16.26000  11.54900  8.45900   1.000 306.56000 ? 118 ILE B C     1 
ATOM   4775 O  O     . ILE B 2 118 ? 17.22200  12.03600  7.85700   1.000 306.85000 ? 118 ILE B O     1 
ATOM   4776 C  CB    . ILE B 2 118 ? 16.59200  9.11700   7.82600   1.000 305.61000 ? 118 ILE B CB    1 
ATOM   4777 C  CG1   . ILE B 2 118 ? 17.06000  8.71800   9.20300   1.000 298.73000 ? 118 ILE B CG1   1 
ATOM   4778 C  CG2   . ILE B 2 118 ? 17.88200  9.52000   7.21900   1.000 303.96000 ? 118 ILE B CG2   1 
ATOM   4779 C  CD1   . ILE B 2 118 ? 16.02800  7.87600   9.91600   1.000 301.76000 ? 118 ILE B CD1   1 
ATOM   4780 N  N     . ASP B 2 119 ? 15.70700  12.16500  9.47900   1.000 307.03000 ? 119 ASP B N     1 
ATOM   4781 C  CA    . ASP B 2 119 ? 15.94400  13.58700  9.65100   1.000 305.53000 ? 119 ASP B CA    1 
ATOM   4782 C  C     . ASP B 2 119 ? 17.21900  13.79100  10.45300  1.000 308.42000 ? 119 ASP B C     1 
ATOM   4783 O  O     . ASP B 2 119 ? 17.20200  13.86200  11.67900  1.000 312.75000 ? 119 ASP B O     1 
ATOM   4784 C  CB    . ASP B 2 119 ? 14.74100  14.25800  10.28700  1.000 310.19000 ? 119 ASP B CB    1 
ATOM   4785 C  CG    . ASP B 2 119 ? 14.73500  15.72400  10.02200  1.000 316.64000 ? 119 ASP B CG    1 
ATOM   4786 O  OD1   . ASP B 2 119 ? 15.36900  16.43600  10.82200  1.000 315.89000 ? 119 ASP B OD1   1 
ATOM   4787 O  OD2   . ASP B 2 119 ? 14.14600  16.15100  8.99900   1.000 326.62000 ? 119 ASP B OD2   1 
ATOM   4788 N  N     . PHE B 2 120 ? 18.33000  13.89100  9.75800   1.000 312.16000 ? 120 PHE B N     1 
ATOM   4789 C  CA    . PHE B 2 120 ? 19.57000  14.29800  10.39500  1.000 318.58000 ? 120 PHE B CA    1 
ATOM   4790 C  C     . PHE B 2 120 ? 19.69400  15.80100  10.51500  1.000 318.50000 ? 120 PHE B C     1 
ATOM   4791 O  O     . PHE B 2 120 ? 20.67500  16.28100  11.08400  1.000 318.82000 ? 120 PHE B O     1 
ATOM   4792 C  CB    . PHE B 2 120 ? 20.76700  13.69800  9.65500   1.000 320.31000 ? 120 PHE B CB    1 
ATOM   4793 C  CG    . PHE B 2 120 ? 20.92800  12.21700  9.92300   1.000 315.28000 ? 120 PHE B CG    1 
ATOM   4794 C  CD1   . PHE B 2 120 ? 20.79500  11.69800  11.20600  1.000 312.36000 ? 120 PHE B CD1   1 
ATOM   4795 C  CD2   . PHE B 2 120 ? 21.25400  11.33200  8.90700   1.000 311.58000 ? 120 PHE B CD2   1 
ATOM   4796 C  CE1   . PHE B 2 120 ? 20.99400  10.33200  11.42000  1.000 308.00000 ? 120 PHE B CE1   1 
ATOM   4797 C  CE2   . PHE B 2 120 ? 21.42600  9.98100   9.17200   1.000 310.43000 ? 120 PHE B CE2   1 
ATOM   4798 C  CZ    . PHE B 2 120 ? 21.31100  9.48900   10.43300  1.000 308.49000 ? 120 PHE B CZ    1 
ATOM   4799 N  N     . LYS B 2 121 ? 18.72900  16.55700  9.99500   1.000 313.43000 ? 121 LYS B N     1 
ATOM   4800 C  CA    . LYS B 2 121 ? 18.85600  18.01100  10.01500  1.000 314.05000 ? 121 LYS B CA    1 
ATOM   4801 C  C     . LYS B 2 121 ? 18.69100  18.58200  11.42700  1.000 313.49000 ? 121 LYS B C     1 
ATOM   4802 O  O     . LYS B 2 121 ? 19.57500  19.30600  11.91800  1.000 311.20000 ? 121 LYS B O     1 
ATOM   4803 C  CB    . LYS B 2 121 ? 17.87300  18.63100  9.04700   1.000 317.69000 ? 121 LYS B CB    1 
ATOM   4804 C  CG    . LYS B 2 121 ? 18.22200  18.41400  7.53500   1.000 311.18000 ? 121 LYS B CG    1 
ATOM   4805 C  CD    . LYS B 2 121 ? 17.19600  17.53100  6.80100   1.000 311.69000 ? 121 LYS B CD    1 
ATOM   4806 C  CE    . LYS B 2 121 ? 15.76600  18.08300  6.83800   1.000 322.02000 ? 121 LYS B CE    1 
ATOM   4807 N  NZ    . LYS B 2 121 ? 14.70800  17.05000  6.56200   1.000 325.28000 ? 121 LYS B NZ    1 
ATOM   4808 N  N     . LYS B 2 122 ? 17.59500  18.23400  12.11900  1.000 301.54000 ? 122 LYS B N     1 
ATOM   4809 C  CA    . LYS B 2 122 ? 17.29900  18.87400  13.40500  1.000 300.00000 ? 122 LYS B CA    1 
ATOM   4810 C  C     . LYS B 2 122 ? 18.32000  18.51000  14.47500  1.000 295.44000 ? 122 LYS B C     1 
ATOM   4811 O  O     . LYS B 2 122 ? 18.72000  19.35200  15.27900  1.000 295.02000 ? 122 LYS B O     1 
ATOM   4812 C  CB    . LYS B 2 122 ? 15.89400  18.47700  13.86700  1.000 302.55000 ? 122 LYS B CB    1 
ATOM   4813 C  CG    . LYS B 2 122 ? 14.78500  19.12800  13.06900  1.000 307.23000 ? 122 LYS B CG    1 
ATOM   4814 C  CD    . LYS B 2 122 ? 14.20700  20.34700  13.79000  1.000 317.00000 ? 122 LYS B CD    1 
ATOM   4815 C  CE    . LYS B 2 122 ? 13.45000  21.26200  12.82600  1.000 307.51000 ? 122 LYS B CE    1 
ATOM   4816 N  NZ    . LYS B 2 122 ? 12.43500  22.11000  13.52400  1.000 290.37000 ? 122 LYS B NZ    1 
ATOM   4817 N  N     . SER B 2 123 ? 18.74500  17.26000  14.50800  1.000 297.05000 ? 123 SER B N     1 
ATOM   4818 C  CA    . SER B 2 123 ? 19.82800  16.84800  15.39100  1.000 292.06000 ? 123 SER B CA    1 
ATOM   4819 C  C     . SER B 2 123 ? 20.37900  15.53000  14.89300  1.000 294.67000 ? 123 SER B C     1 
ATOM   4820 O  O     . SER B 2 123 ? 19.61400  14.65900  14.45000  1.000 295.61000 ? 123 SER B O     1 
ATOM   4821 C  CB    . SER B 2 123 ? 19.40200  16.69900  16.86000  1.000 300.13000 ? 123 SER B CB    1 
ATOM   4822 O  OG    . SER B 2 123 ? 20.37700  15.95600  17.56700  1.000 305.29000 ? 123 SER B OG    1 
ATOM   4823 N  N     . TRP B 2 124 ? 21.71900  15.40500  14.94800  1.000 299.09000 ? 124 TRP B N     1 
ATOM   4824 C  CA    . TRP B 2 124 ? 22.34600  14.17800  14.46500  1.000 300.00000 ? 124 TRP B CA    1 
ATOM   4825 C  C     . TRP B 2 124 ? 21.95000  12.98500  15.31300  1.000 294.26000 ? 124 TRP B C     1 
ATOM   4826 O  O     . TRP B 2 124 ? 21.87400  11.84400  14.82600  1.000 293.88000 ? 124 TRP B O     1 
ATOM   4827 C  CB    . TRP B 2 124 ? 23.85900  14.35100  14.45400  1.000 297.58000 ? 124 TRP B CB    1 
ATOM   4828 C  CG    . TRP B 2 124 ? 24.29400  14.94800  13.19000  1.000 298.38000 ? 124 TRP B CG    1 
ATOM   4829 C  CD1   . TRP B 2 124 ? 23.51200  15.58600  12.28400  1.000 299.45000 ? 124 TRP B CD1   1 
ATOM   4830 C  CD2   . TRP B 2 124 ? 25.60500  14.93900  12.64500  1.000 297.24000 ? 124 TRP B CD2   1 
ATOM   4831 N  NE1   . TRP B 2 124 ? 24.24600  15.99000  11.20700  1.000 295.67000 ? 124 TRP B NE1   1 
ATOM   4832 C  CE2   . TRP B 2 124 ? 25.54100  15.60700  11.40100  1.000 295.43000 ? 124 TRP B CE2   1 
ATOM   4833 C  CE3   . TRP B 2 124 ? 26.83500  14.44200  13.08600  1.000 299.40000 ? 124 TRP B CE3   1 
ATOM   4834 C  CZ2   . TRP B 2 124 ? 26.65200  15.79300  10.59500  1.000 297.64000 ? 124 TRP B CZ2   1 
ATOM   4835 C  CZ3   . TRP B 2 124 ? 27.93400  14.62700  12.29300  1.000 303.60000 ? 124 TRP B CZ3   1 
ATOM   4836 C  CH2   . TRP B 2 124 ? 27.84100  15.29800  11.05600  1.000 304.19000 ? 124 TRP B CH2   1 
ATOM   4837 N  N     . ALA B 2 125 ? 21.68000  13.23900  16.58100  1.000 292.98000 ? 125 ALA B N     1 
ATOM   4838 C  CA    . ALA B 2 125 ? 21.32500  12.14100  17.45100  1.000 297.84000 ? 125 ALA B CA    1 
ATOM   4839 C  C     . ALA B 2 125 ? 19.91600  11.64500  17.17600  1.000 297.78000 ? 125 ALA B C     1 
ATOM   4840 O  O     . ALA B 2 125 ? 19.73600  10.46600  16.82900  1.000 299.38000 ? 125 ALA B O     1 
ATOM   4841 C  CB    . ALA B 2 125 ? 21.49900  12.57300  18.89700  1.000 305.23000 ? 125 ALA B CB    1 
ATOM   4842 N  N     . LYS B 2 126 ? 18.92200  12.53800  17.26400  1.000 297.39000 ? 126 LYS B N     1 
ATOM   4843 C  CA    . LYS B 2 126 ? 17.54400  12.12600  17.06000  1.000 302.80000 ? 126 LYS B CA    1 
ATOM   4844 C  C     . LYS B 2 126 ? 17.42900  11.21300  15.86600  1.000 301.78000 ? 126 LYS B C     1 
ATOM   4845 O  O     . LYS B 2 126 ? 16.82200  10.14600  15.94300  1.000 305.39000 ? 126 LYS B O     1 
ATOM   4846 C  CB    . LYS B 2 126 ? 16.66900  13.35100  16.83100  1.000 306.78000 ? 126 LYS B CB    1 
ATOM   4847 C  CG    . LYS B 2 126 ? 15.23300  12.99700  16.83500  1.000 314.59000 ? 126 LYS B CG    1 
ATOM   4848 C  CD    . LYS B 2 126 ? 14.92300  12.27900  18.14200  1.000 309.76000 ? 126 LYS B CD    1 
ATOM   4849 C  CE    . LYS B 2 126 ? 13.43500  12.18200  18.34500  1.000 305.89000 ? 126 LYS B CE    1 
ATOM   4850 N  NZ    . LYS B 2 126 ? 12.85800  11.49500  17.16100  1.000 313.29000 ? 126 LYS B NZ    1 
ATOM   4851 N  N     . GLY B 2 127 ? 18.08000  11.59100  14.78100  1.000 301.21000 ? 127 GLY B N     1 
ATOM   4852 C  CA    . GLY B 2 127 ? 18.05300  10.76800  13.60500  1.000 305.15000 ? 127 GLY B CA    1 
ATOM   4853 C  C     . GLY B 2 127 ? 18.84800  9.48200   13.75200  1.000 304.04000 ? 127 GLY B C     1 
ATOM   4854 O  O     . GLY B 2 127 ? 18.46000  8.44200   13.19900  1.000 310.84000 ? 127 GLY B O     1 
ATOM   4855 N  N     . LEU B 2 128 ? 20.00700  9.52800   14.42800  1.000 297.49000 ? 128 LEU B N     1 
ATOM   4856 C  CA    . LEU B 2 128 ? 20.59600  8.23800   14.74600  1.000 295.86000 ? 128 LEU B CA    1 
ATOM   4857 C  C     . LEU B 2 128 ? 19.53600  7.36100   15.40200  1.000 303.51000 ? 128 LEU B C     1 
ATOM   4858 O  O     . LEU B 2 128 ? 19.29200  6.24100   14.94100  1.000 310.77000 ? 128 LEU B O     1 
ATOM   4859 C  CB    . LEU B 2 128 ? 21.85400  8.39900   15.60600  1.000 291.40000 ? 128 LEU B CB    1 
ATOM   4860 C  CG    . LEU B 2 128 ? 23.08300  7.65600   15.05800  1.000 288.57000 ? 128 LEU B CG    1 
ATOM   4861 C  CD1   . LEU B 2 128 ? 23.54800  6.54700   15.99400  1.000 294.17000 ? 128 LEU B CD1   1 
ATOM   4862 C  CD2   . LEU B 2 128 ? 22.81400  7.06500   13.69200  1.000 289.37000 ? 128 LEU B CD2   1 
ATOM   4863 N  N     . GLN B 2 129 ? 18.78800  7.91300   16.37300  1.000 291.80000 ? 129 GLN B N     1 
ATOM   4864 C  CA    . GLN B 2 129 ? 17.65600  7.18600   16.95200  1.000 293.27000 ? 129 GLN B CA    1 
ATOM   4865 C  C     . GLN B 2 129 ? 16.61700  6.82200   15.90400  1.000 296.56000 ? 129 GLN B C     1 
ATOM   4866 O  O     . GLN B 2 129 ? 16.01100  5.74300   15.96600  1.000 296.53000 ? 129 GLN B O     1 
ATOM   4867 C  CB    . GLN B 2 129 ? 16.98200  8.01400   18.04900  1.000 292.48000 ? 129 GLN B CB    1 
ATOM   4868 C  CG    . GLN B 2 129 ? 15.54500  7.58900   18.36400  1.000 302.16000 ? 129 GLN B CG    1 
ATOM   4869 C  CD    . GLN B 2 129 ? 15.49200  6.43800   19.34800  1.000 315.31000 ? 129 GLN B CD    1 
ATOM   4870 O  OE1   . GLN B 2 129 ? 16.52500  5.93900   19.77600  1.000 320.82000 ? 129 GLN B OE1   1 
ATOM   4871 N  NE2   . GLN B 2 129 ? 14.29200  6.01800   19.71900  1.000 307.64000 ? 129 GLN B NE2   1 
ATOM   4872 N  N     . ASP B 2 130 ? 16.34200  7.73100   14.97200  1.000 310.40000 ? 130 ASP B N     1 
ATOM   4873 C  CA    . ASP B 2 130 ? 15.30800  7.41700   13.99400  1.000 313.80000 ? 130 ASP B CA    1 
ATOM   4874 C  C     . ASP B 2 130 ? 15.78800  6.33300   13.03200  1.000 315.64000 ? 130 ASP B C     1 
ATOM   4875 O  O     . ASP B 2 130 ? 15.02400  5.41900   12.69200  1.000 313.40000 ? 130 ASP B O     1 
ATOM   4876 C  CB    . ASP B 2 130 ? 14.86600  8.67900   13.23700  1.000 319.18000 ? 130 ASP B CB    1 
ATOM   4877 C  CG    . ASP B 2 130 ? 13.81700  9.48900   14.00000  1.000 318.44000 ? 130 ASP B CG    1 
ATOM   4878 O  OD1   . ASP B 2 130 ? 13.55800  9.15400   15.17400  1.000 315.35000 ? 130 ASP B OD1   1 
ATOM   4879 O  OD2   . ASP B 2 130 ? 13.25100  10.45700  13.42500  1.000 320.62000 ? 130 ASP B OD2   1 
ATOM   4880 N  N     . LEU B 2 131 ? 17.06700  6.39500   12.61700  1.000 319.72000 ? 131 LEU B N     1 
ATOM   4881 C  CA    . LEU B 2 131 ? 17.60900  5.41400   11.66800  1.000 321.55000 ? 131 LEU B CA    1 
ATOM   4882 C  C     . LEU B 2 131 ? 17.60000  4.02100   12.27400  1.000 318.37000 ? 131 LEU B C     1 
ATOM   4883 O  O     . LEU B 2 131 ? 17.26000  3.02800   11.60900  1.000 317.27000 ? 131 LEU B O     1 
ATOM   4884 C  CB    . LEU B 2 131 ? 19.03900  5.79800   11.24900  1.000 316.28000 ? 131 LEU B CB    1 
ATOM   4885 C  CG    . LEU B 2 131 ? 19.73700  5.04600   10.10900  1.000 310.50000 ? 131 LEU B CG    1 
ATOM   4886 C  CD1   . LEU B 2 131 ? 19.15200  5.44000   8.75600   1.000 307.64000 ? 131 LEU B CD1   1 
ATOM   4887 C  CD2   . LEU B 2 131 ? 21.26600  5.20900   10.08400  1.000 302.94000 ? 131 LEU B CD2   1 
ATOM   4888 N  N     . LEU B 2 132 ? 17.99200  3.93300   13.54500  1.000 319.45000 ? 132 LEU B N     1 
ATOM   4889 C  CA    . LEU B 2 132 ? 17.95600  2.65600   14.24200  1.000 323.46000 ? 132 LEU B CA    1 
ATOM   4890 C  C     . LEU B 2 132 ? 16.52300  2.25200   14.58600  1.000 321.06000 ? 132 LEU B C     1 
ATOM   4891 O  O     . LEU B 2 132 ? 16.12700  1.10400   14.35300  1.000 319.49000 ? 132 LEU B O     1 
ATOM   4892 C  CB    . LEU B 2 132 ? 18.81800  2.73100   15.50800  1.000 335.21000 ? 132 LEU B CB    1 
ATOM   4893 C  CG    . LEU B 2 132 ? 20.19700  3.40500   15.48400  1.000 329.10000 ? 132 LEU B CG    1 
ATOM   4894 C  CD1   . LEU B 2 132 ? 20.73900  3.70500   16.89800  1.000 321.92000 ? 132 LEU B CD1   1 
ATOM   4895 C  CD2   . LEU B 2 132 ? 21.22000  2.60600   14.69300  1.000 322.19000 ? 132 LEU B CD2   1 
ATOM   4896 N  N     . ASP B 2 133 ? 15.71900  3.17500   15.13000  1.000 319.74000 ? 133 ASP B N     1 
ATOM   4897 C  CA    . ASP B 2 133 ? 14.36000  2.78700   15.46900  1.000 317.52000 ? 133 ASP B CA    1 
ATOM   4898 C  C     . ASP B 2 133 ? 13.62600  2.32400   14.22500  1.000 318.26000 ? 133 ASP B C     1 
ATOM   4899 O  O     . ASP B 2 133 ? 12.83400  1.36800   14.27500  1.000 323.63000 ? 133 ASP B O     1 
ATOM   4900 C  CB    . ASP B 2 133 ? 13.62200  3.93700   16.16800  1.000 313.45000 ? 133 ASP B CB    1 
ATOM   4901 C  CG    . ASP B 2 133 ? 12.87800  3.46000   17.39000  1.000 316.07000 ? 133 ASP B CG    1 
ATOM   4902 O  OD1   . ASP B 2 133 ? 11.89600  2.70800   17.23200  1.000 319.69000 ? 133 ASP B OD1   1 
ATOM   4903 O  OD2   . ASP B 2 133 ? 13.29500  3.82000   18.51300  1.000 311.22000 ? 133 ASP B OD2   1 
ATOM   4904 N  N     . ALA B 2 134 ? 13.92100  2.95800   13.09000  1.000 317.41000 ? 134 ALA B N     1 
ATOM   4905 C  CA    . ALA B 2 134 ? 13.59200  2.33700   11.82500  1.000 327.88000 ? 134 ALA B CA    1 
ATOM   4906 C  C     . ALA B 2 134 ? 14.24500  0.96400   11.68800  1.000 324.87000 ? 134 ALA B C     1 
ATOM   4907 O  O     . ALA B 2 134 ? 13.65300  0.06100   11.08900  1.000 335.22000 ? 134 ALA B O     1 
ATOM   4908 C  CB    . ALA B 2 134 ? 13.99900  3.27500   10.68400  1.000 332.23000 ? 134 ALA B CB    1 
ATOM   4909 N  N     . PHE B 2 135 ? 15.45200  0.76900   12.23900  1.000 316.84000 ? 135 PHE B N     1 
ATOM   4910 C  CA    . PHE B 2 135 ? 16.10100  -0.54600  12.10500  1.000 313.95000 ? 135 PHE B CA    1 
ATOM   4911 C  C     . PHE B 2 135 ? 15.52500  -1.55100  13.10000  1.000 316.10000 ? 135 PHE B C     1 
ATOM   4912 O  O     . PHE B 2 135 ? 15.98400  -2.69900  13.19400  1.000 315.72000 ? 135 PHE B O     1 
ATOM   4913 C  CB    . PHE B 2 135 ? 17.61200  -0.43900  12.34000  1.000 306.82000 ? 135 PHE B CB    1 
ATOM   4914 C  CG    . PHE B 2 135 ? 18.39000  0.18400   11.21100  1.000 305.69000 ? 135 PHE B CG    1 
ATOM   4915 C  CD1   . PHE B 2 135 ? 17.94900  0.11800   9.90900   1.000 313.55000 ? 135 PHE B CD1   1 
ATOM   4916 C  CD2   . PHE B 2 135 ? 19.59300  0.83000   11.47100  1.000 303.17000 ? 135 PHE B CD2   1 
ATOM   4917 C  CE1   . PHE B 2 135 ? 18.67700  0.68600   8.87800   1.000 308.24000 ? 135 PHE B CE1   1 
ATOM   4918 C  CE2   . PHE B 2 135 ? 20.31700  1.40700   10.45000  1.000 301.55000 ? 135 PHE B CE2   1 
ATOM   4919 C  CZ    . PHE B 2 135 ? 19.85600  1.34600   9.15400   1.000 300.06000 ? 135 PHE B CZ    1 
ATOM   4920 N  N     . GLU B 2 136 ? 14.54700  -1.11500  13.88700  1.000 303.26000 ? 136 GLU B N     1 
ATOM   4921 C  CA    . GLU B 2 136 ? 13.87900  -2.01700  14.81100  1.000 310.89000 ? 136 GLU B CA    1 
ATOM   4922 C  C     . GLU B 2 136 ? 12.59700  -2.54100  14.19000  1.000 310.70000 ? 136 GLU B C     1 
ATOM   4923 O  O     . GLU B 2 136 ? 12.29900  -3.74700  14.25000  1.000 315.20000 ? 136 GLU B O     1 
ATOM   4924 C  CB    . GLU B 2 136 ? 13.58900  -1.29900  16.12900  1.000 315.96000 ? 136 GLU B CB    1 
ATOM   4925 C  CG    . GLU B 2 136 ? 12.45600  -1.90300  16.87300  1.000 323.75000 ? 136 GLU B CG    1 
ATOM   4926 C  CD    . GLU B 2 136 ? 12.37700  -1.42200  18.28800  1.000 336.52000 ? 136 GLU B CD    1 
ATOM   4927 O  OE1   . GLU B 2 136 ? 13.44000  -1.41600  18.95700  1.000 344.62000 ? 136 GLU B OE1   1 
ATOM   4928 O  OE2   . GLU B 2 136 ? 11.26200  -1.04100  18.72100  1.000 336.19000 ? 136 GLU B OE2   1 
ATOM   4929 N  N     . LYS B 2 137 ? 11.84200  -1.64000  13.56200  1.000 306.28000 ? 137 LYS B N     1 
ATOM   4930 C  CA    . LYS B 2 137 ? 10.53000  -1.98800  13.04800  1.000 311.02000 ? 137 LYS B CA    1 
ATOM   4931 C  C     . LYS B 2 137 ? 10.61600  -3.02100  11.92800  1.000 326.25000 ? 137 LYS B C     1 
ATOM   4932 O  O     . LYS B 2 137 ? 9.80800   -3.95600  11.90000  1.000 329.94000 ? 137 LYS B O     1 
ATOM   4933 C  CB    . LYS B 2 137 ? 9.83500   -0.71200  12.59000  1.000 314.64000 ? 137 LYS B CB    1 
ATOM   4934 C  CG    . LYS B 2 137 ? 9.45500   0.24300   13.74400  1.000 314.76000 ? 137 LYS B CG    1 
ATOM   4935 C  CD    . LYS B 2 137 ? 8.01400   0.72500   13.57100  1.000 313.69000 ? 137 LYS B CD    1 
ATOM   4936 C  CE    . LYS B 2 137 ? 7.39500   1.31300   14.83200  1.000 297.25000 ? 137 LYS B CE    1 
ATOM   4937 N  NZ    . LYS B 2 137 ? 7.42700   2.79700   14.78800  1.000 287.40000 ? 137 LYS B NZ    1 
ATOM   4938 N  N     . GLN B 2 138 ? 11.58500  -2.87500  11.00500  1.000 341.28000 ? 138 GLN B N     1 
ATOM   4939 C  CA    . GLN B 2 138 ? 11.99700  -3.94400  10.09600  1.000 343.69000 ? 138 GLN B CA    1 
ATOM   4940 C  C     . GLN B 2 138 ? 13.26700  -4.56200  10.69500  1.000 341.60000 ? 138 GLN B C     1 
ATOM   4941 O  O     . GLN B 2 138 ? 14.11000  -3.84600  11.25700  1.000 334.42000 ? 138 GLN B O     1 
ATOM   4942 C  CB    . GLN B 2 138 ? 12.19000  -3.46800  8.60500   1.000 325.79000 ? 138 GLN B CB    1 
ATOM   4943 C  CG    . GLN B 2 138 ? 12.64700  -1.98300  8.23600   1.000 315.56000 ? 138 GLN B CG    1 
ATOM   4944 C  CD    . GLN B 2 138 ? 11.65300  -1.19200  7.34200   1.000 319.73000 ? 138 GLN B CD    1 
ATOM   4945 O  OE1   . GLN B 2 138 ? 11.21800  -1.66700  6.29100   1.000 322.25000 ? 138 GLN B OE1   1 
ATOM   4946 N  NE2   . GLN B 2 138 ? 11.31500  0.03200   7.76800   1.000 323.34000 ? 138 GLN B NE2   1 
ATOM   4947 N  N     . ASN B 2 139 ? 13.36800  -5.90300  10.68000  1.000 347.22000 ? 139 ASN B N     1 
ATOM   4948 C  CA    . ASN B 2 139 ? 14.46200  -6.59200  11.39900  1.000 337.82000 ? 139 ASN B CA    1 
ATOM   4949 C  C     . ASN B 2 139 ? 15.70200  -6.68300  10.50300  1.000 345.61000 ? 139 ASN B C     1 
ATOM   4950 O  O     . ASN B 2 139 ? 15.95500  -7.67400  9.80700   1.000 344.39000 ? 139 ASN B O     1 
ATOM   4951 C  CB    . ASN B 2 139 ? 14.00200  -7.95600  11.92700  1.000 326.87000 ? 139 ASN B CB    1 
ATOM   4952 C  CG    . ASN B 2 139 ? 13.45000  -7.88600  13.35800  1.000 318.20000 ? 139 ASN B CG    1 
ATOM   4953 O  OD1   . ASN B 2 139 ? 13.97300  -7.15300  14.20400  1.000 334.59000 ? 139 ASN B OD1   1 
ATOM   4954 N  ND2   . ASN B 2 139 ? 12.42600  -8.66700  13.63100  1.000 309.97000 ? 139 ASN B ND2   1 
ATOM   4955 N  N     . VAL B 2 140 ? 16.44900  -5.57700  10.48600  1.000 362.08000 ? 140 VAL B N     1 
ATOM   4956 C  CA    . VAL B 2 140 ? 17.77700  -5.49600  9.91800   1.000 360.86000 ? 140 VAL B CA    1 
ATOM   4957 C  C     . VAL B 2 140 ? 18.77400  -6.15200  10.96900  1.000 362.50000 ? 140 VAL B C     1 
ATOM   4958 O  O     . VAL B 2 140 ? 18.58400  -5.90300  12.17300  1.000 357.12000 ? 140 VAL B O     1 
ATOM   4959 C  CB    . VAL B 2 140 ? 18.18900  -4.04600  9.61000   1.000 347.78000 ? 140 VAL B CB    1 
ATOM   4960 C  CG1   . VAL B 2 140 ? 19.43600  -3.89600  8.75100   1.000 324.20000 ? 140 VAL B CG1   1 
ATOM   4961 C  CG2   . VAL B 2 140 ? 17.01000  -3.39000  8.94900   1.000 335.98000 ? 140 VAL B CG2   1 
ATOM   4962 N  N     . PRO B 2 141 ? 19.71400  -6.93800  10.47100  1.000 357.60000 ? 141 PRO B N     1 
ATOM   4963 C  CA    . PRO B 2 141 ? 20.49900  -7.78400  11.40500  1.000 343.75000 ? 141 PRO B CA    1 
ATOM   4964 C  C     . PRO B 2 141 ? 21.61500  -7.04300  12.11300  1.000 347.68000 ? 141 PRO B C     1 
ATOM   4965 O  O     . PRO B 2 141 ? 22.24700  -6.13700  11.56100  1.000 354.04000 ? 141 PRO B O     1 
ATOM   4966 C  CB    . PRO B 2 141 ? 21.07500  -8.87200  10.48500  1.000 321.99000 ? 141 PRO B CB    1 
ATOM   4967 C  CG    . PRO B 2 141 ? 21.13100  -8.23300  9.13700   1.000 326.23000 ? 141 PRO B CG    1 
ATOM   4968 C  CD    . PRO B 2 141 ? 20.00200  -7.24800  9.04600   1.000 342.03000 ? 141 PRO B CD    1 
ATOM   4969 N  N     . LYS B 2 142 ? 21.86800  -7.45900  13.35800  1.000 322.06000 ? 142 LYS B N     1 
ATOM   4970 C  CA    . LYS B 2 142 ? 22.77600  -6.72300  14.23200  1.000 318.00000 ? 142 LYS B CA    1 
ATOM   4971 C  C     . LYS B 2 142 ? 23.61700  -7.71200  15.03800  1.000 313.94000 ? 142 LYS B C     1 
ATOM   4972 O  O     . LYS B 2 142 ? 23.21600  -8.85700  15.26800  1.000 323.53000 ? 142 LYS B O     1 
ATOM   4973 C  CB    . LYS B 2 142 ? 21.94900  -5.73900  15.10000  1.000 313.94000 ? 142 LYS B CB    1 
ATOM   4974 C  CG    . LYS B 2 142 ? 22.73200  -4.92100  16.14700  1.000 311.41000 ? 142 LYS B CG    1 
ATOM   4975 C  CD    . LYS B 2 142 ? 21.81300  -3.98600  16.95700  1.000 306.17000 ? 142 LYS B CD    1 
ATOM   4976 C  CE    . LYS B 2 142 ? 22.59100  -3.34400  18.12200  1.000 312.69000 ? 142 LYS B CE    1 
ATOM   4977 N  NZ    . LYS B 2 142 ? 22.07300  -1.99800  18.51100  1.000 314.97000 ? 142 LYS B NZ    1 
ATOM   4978 N  N     . LYS B 2 143 ? 24.80500  -7.27800  15.41800  1.000 304.49000 ? 143 LYS B N     1 
ATOM   4979 C  CA    . LYS B 2 143 ? 25.59400  -7.95900  16.42000  1.000 305.15000 ? 143 LYS B CA    1 
ATOM   4980 C  C     . LYS B 2 143 ? 25.53500  -7.16600  17.71200  1.000 312.99000 ? 143 LYS B C     1 
ATOM   4981 O  O     . LYS B 2 143 ? 25.25000  -5.95400  17.69300  1.000 319.30000 ? 143 LYS B O     1 
ATOM   4982 C  CB    . LYS B 2 143 ? 27.06600  -8.12100  16.01700  1.000 294.58000 ? 143 LYS B CB    1 
ATOM   4983 C  CG    . LYS B 2 143 ? 27.31100  -8.74400  14.65400  1.000 289.54000 ? 143 LYS B CG    1 
ATOM   4984 C  CD    . LYS B 2 143 ? 28.18000  -7.84200  13.77000  1.000 303.06000 ? 143 LYS B CD    1 
ATOM   4985 C  CE    . LYS B 2 143 ? 29.46900  -7.42700  14.45500  1.000 307.08000 ? 143 LYS B CE    1 
ATOM   4986 N  NZ    . LYS B 2 143 ? 30.34200  -6.52800  13.64700  1.000 303.46000 ? 143 LYS B NZ    1 
ATOM   4987 N  N     . PRO B 2 144 ? 25.75700  -7.80200  18.86500  1.000 310.03000 ? 144 PRO B N     1 
ATOM   4988 C  CA    . PRO B 2 144 ? 25.78900  -7.04700  20.11700  1.000 305.39000 ? 144 PRO B CA    1 
ATOM   4989 C  C     . PRO B 2 144 ? 26.92700  -6.03900  20.10000  1.000 305.81000 ? 144 PRO B C     1 
ATOM   4990 O  O     . PRO B 2 144 ? 28.08500  -6.37400  19.76300  1.000 314.31000 ? 144 PRO B O     1 
ATOM   4991 C  CB    . PRO B 2 144 ? 26.02200  -8.10100  21.19900  1.000 305.14000 ? 144 PRO B CB    1 
ATOM   4992 C  CG    . PRO B 2 144 ? 26.75400  -9.13000  20.45700  1.000 306.38000 ? 144 PRO B CG    1 
ATOM   4993 C  CD    . PRO B 2 144 ? 26.12000  -9.20800  19.10700  1.000 310.96000 ? 144 PRO B CD    1 
ATOM   4994 N  N     . PRO B 2 145 ? 26.63100  -4.79100  20.48800  1.000 311.49000 ? 145 PRO B N     1 
ATOM   4995 C  CA    . PRO B 2 145 ? 27.55300  -3.69200  20.14100  1.000 319.77000 ? 145 PRO B CA    1 
ATOM   4996 C  C     . PRO B 2 145 ? 28.94600  -3.88400  20.72000  1.000 318.71000 ? 145 PRO B C     1 
ATOM   4997 O  O     . PRO B 2 145 ? 29.10900  -4.31200  21.86300  1.000 314.20000 ? 145 PRO B O     1 
ATOM   4998 C  CB    . PRO B 2 145 ? 26.87800  -2.43300  20.70100  1.000 312.92000 ? 145 PRO B CB    1 
ATOM   4999 C  CG    . PRO B 2 145 ? 25.85200  -2.92800  21.65300  1.000 304.95000 ? 145 PRO B CG    1 
ATOM   5000 C  CD    . PRO B 2 145 ? 25.48200  -4.34100  21.30200  1.000 299.36000 ? 145 PRO B CD    1 
ATOM   5001 N  N     . ASP B 2 146 ? 29.95300  -3.68100  19.86600  1.000 313.32000 ? 146 ASP B N     1 
ATOM   5002 C  CA    . ASP B 2 146 ? 31.34900  -3.61200  20.29100  1.000 300.54000 ? 146 ASP B CA    1 
ATOM   5003 C  C     . ASP B 2 146 ? 31.94900  -2.35600  19.68600  1.000 290.65000 ? 146 ASP B C     1 
ATOM   5004 O  O     . ASP B 2 146 ? 32.61100  -2.42300  18.64400  1.000 286.23000 ? 146 ASP B O     1 
ATOM   5005 C  CB    . ASP B 2 146 ? 32.15400  -4.83700  19.88400  1.000 301.78000 ? 146 ASP B CB    1 
ATOM   5006 C  CG    . ASP B 2 146 ? 33.37500  -5.00700  20.74600  1.000 311.97000 ? 146 ASP B CG    1 
ATOM   5007 O  OD1   . ASP B 2 146 ? 33.39900  -4.38900  21.81900  1.000 310.86000 ? 146 ASP B OD1   1 
ATOM   5008 O  OD2   . ASP B 2 146 ? 34.31200  -5.74300  20.39200  1.000 300.97000 ? 146 ASP B OD2   1 
ATOM   5009 N  N     . HIS B 2 147 ? 31.73400  -1.22400  20.35700  1.000 295.67000 ? 147 HIS B N     1 
ATOM   5010 C  CA    . HIS B 2 147 ? 32.44200  -0.01100  19.99100  1.000 293.52000 ? 147 HIS B CA    1 
ATOM   5011 C  C     . HIS B 2 147 ? 33.93400  -0.26800  19.80000  1.000 295.94000 ? 147 HIS B C     1 
ATOM   5012 O  O     . HIS B 2 147 ? 34.61100  0.52800   19.14700  1.000 297.15000 ? 147 HIS B O     1 
ATOM   5013 C  CB    . HIS B 2 147 ? 32.21300  1.07800   21.05500  1.000 289.37000 ? 147 HIS B CB    1 
ATOM   5014 C  CG    . HIS B 2 147 ? 30.77300  1.45300   21.26000  1.000 292.27000 ? 147 HIS B CG    1 
ATOM   5015 N  ND1   . HIS B 2 147 ? 30.18100  2.52200   20.61900  1.000 295.81000 ? 147 HIS B ND1   1 
ATOM   5016 C  CD2   . HIS B 2 147 ? 29.82100  0.92300   22.06400  1.000 288.74000 ? 147 HIS B CD2   1 
ATOM   5017 C  CE1   . HIS B 2 147 ? 28.92300  2.62400   21.00800  1.000 296.04000 ? 147 HIS B CE1   1 
ATOM   5018 N  NE2   . HIS B 2 147 ? 28.67900  1.66500   21.88500  1.000 291.01000 ? 147 HIS B NE2   1 
ATOM   5019 N  N     . SER B 2 148 ? 34.47300  -1.36000  20.34100  1.000 293.60000 ? 148 SER B N     1 
ATOM   5020 C  CA    . SER B 2 148 ? 35.87800  -1.64900  20.09300  1.000 294.12000 ? 148 SER B CA    1 
ATOM   5021 C  C     . SER B 2 148 ? 36.15300  -1.76500  18.60600  1.000 289.62000 ? 148 SER B C     1 
ATOM   5022 O  O     . SER B 2 148 ? 37.18600  -1.29900  18.11600  1.000 289.03000 ? 148 SER B O     1 
ATOM   5023 C  CB    . SER B 2 148 ? 36.29300  -2.93000  20.79700  1.000 298.71000 ? 148 SER B CB    1 
ATOM   5024 O  OG    . SER B 2 148 ? 37.70900  -3.03100  20.78600  1.000 298.25000 ? 148 SER B OG    1 
ATOM   5025 N  N     . LYS B 2 149 ? 35.23900  -2.39100  17.87400  1.000 285.03000 ? 149 LYS B N     1 
ATOM   5026 C  CA    . LYS B 2 149 ? 35.32500  -2.35800  16.42700  1.000 286.70000 ? 149 LYS B CA    1 
ATOM   5027 C  C     . LYS B 2 149 ? 35.25200  -0.92400  15.91800  1.000 286.72000 ? 149 LYS B C     1 
ATOM   5028 O  O     . LYS B 2 149 ? 36.03500  -0.52900  15.04500  1.000 285.31000 ? 149 LYS B O     1 
ATOM   5029 C  CB    . LYS B 2 149 ? 34.21100  -3.20200  15.83600  1.000 289.29000 ? 149 LYS B CB    1 
ATOM   5030 C  CG    . LYS B 2 149 ? 34.54900  -3.70500  14.49700  1.000 294.57000 ? 149 LYS B CG    1 
ATOM   5031 C  CD    . LYS B 2 149 ? 33.35800  -4.34500  13.88700  1.000 306.73000 ? 149 LYS B CD    1 
ATOM   5032 C  CE    . LYS B 2 149 ? 33.78300  -5.04000  12.64100  1.000 307.51000 ? 149 LYS B CE    1 
ATOM   5033 N  NZ    . LYS B 2 149 ? 34.74800  -4.17400  11.94300  1.000 300.21000 ? 149 LYS B NZ    1 
ATOM   5034 N  N     . SER B 2 150 ? 34.32800  -0.12900  16.47600  1.000 295.87000 ? 150 SER B N     1 
ATOM   5035 C  CA    . SER B 2 150 ? 34.11800  1.25900   16.07100  1.000 294.43000 ? 150 SER B CA    1 
ATOM   5036 C  C     . SER B 2 150 ? 35.45400  1.95000   15.84000  1.000 288.90000 ? 150 SER B C     1 
ATOM   5037 O  O     . SER B 2 150 ? 35.81900  2.28300   14.70800  1.000 284.05000 ? 150 SER B O     1 
ATOM   5038 C  CB    . SER B 2 150 ? 33.28200  1.99500   17.14400  1.000 295.71000 ? 150 SER B CB    1 
ATOM   5039 O  OG    . SER B 2 150 ? 33.17500  3.40600   16.95100  1.000 290.21000 ? 150 SER B OG    1 
ATOM   5040 N  N     . ASN B 2 151 ? 36.23000  2.10400   16.90300  1.000 289.37000 ? 151 ASN B N     1 
ATOM   5041 C  CA    . ASN B 2 151 ? 37.44800  2.89500   16.84500  1.000 289.18000 ? 151 ASN B CA    1 
ATOM   5042 C  C     . ASN B 2 151 ? 38.69600  2.08600   16.57100  1.000 289.14000 ? 151 ASN B C     1 
ATOM   5043 O  O     . ASN B 2 151 ? 39.77500  2.66400   16.50300  1.000 293.22000 ? 151 ASN B O     1 
ATOM   5044 C  CB    . ASN B 2 151 ? 37.64100  3.64700   18.14000  1.000 289.33000 ? 151 ASN B CB    1 
ATOM   5045 C  CG    . ASN B 2 151 ? 37.86000  2.71800   19.32200  1.000 288.87000 ? 151 ASN B CG    1 
ATOM   5046 O  OD1   . ASN B 2 151 ? 37.35700  1.58000   19.35400  1.000 290.26000 ? 151 ASN B OD1   1 
ATOM   5047 N  ND2   . ASN B 2 151 ? 38.64300  3.20100   20.29200  1.000 288.03000 ? 151 ASN B ND2   1 
ATOM   5048 N  N     . LEU B 2 152 ? 38.60800  0.76300   16.50500  1.000 280.56000 ? 152 LEU B N     1 
ATOM   5049 C  CA    . LEU B 2 152 ? 39.67000  0.03800   15.82300  1.000 281.30000 ? 152 LEU B CA    1 
ATOM   5050 C  C     . LEU B 2 152 ? 39.78800  0.58400   14.42000  1.000 276.41000 ? 152 LEU B C     1 
ATOM   5051 O  O     . LEU B 2 152 ? 40.88000  0.74600   13.85700  1.000 277.01000 ? 152 LEU B O     1 
ATOM   5052 C  CB    . LEU B 2 152 ? 39.36700  -1.46100  15.77600  1.000 284.42000 ? 152 LEU B CB    1 
ATOM   5053 C  CG    . LEU B 2 152 ? 40.04400  -2.07100  14.54000  1.000 278.63000 ? 152 LEU B CG    1 
ATOM   5054 C  CD1   . LEU B 2 152 ? 41.58000  -2.02000  14.59500  1.000 277.21000 ? 152 LEU B CD1   1 
ATOM   5055 C  CD2   . LEU B 2 152 ? 39.60000  -3.48200  14.33100  1.000 287.53000 ? 152 LEU B CD2   1 
ATOM   5056 N  N     . LEU B 2 153 ? 38.64100  0.90400   13.86300  1.000 278.50000 ? 153 LEU B N     1 
ATOM   5057 C  CA    . LEU B 2 153 ? 38.58500  1.53200   12.57000  1.000 275.99000 ? 153 LEU B CA    1 
ATOM   5058 C  C     . LEU B 2 153 ? 39.15100  2.92400   12.64700  1.000 278.38000 ? 153 LEU B C     1 
ATOM   5059 O  O     . LEU B 2 153 ? 40.21300  3.19500   12.08300  1.000 275.36000 ? 153 LEU B O     1 
ATOM   5060 C  CB    . LEU B 2 153 ? 37.14700  1.56800   12.10900  1.000 273.33000 ? 153 LEU B CB    1 
ATOM   5061 C  CG    . LEU B 2 153 ? 36.66400  0.18100   11.66200  1.000 286.39000 ? 153 LEU B CG    1 
ATOM   5062 C  CD1   . LEU B 2 153 ? 37.37100  -1.08100  12.29200  1.000 290.42000 ? 153 LEU B CD1   1 
ATOM   5063 C  CD2   . LEU B 2 153 ? 35.19600  0.17100   11.88600  1.000 294.74000 ? 153 LEU B CD2   1 
ATOM   5064 N  N     . TYR B 2 154 ? 38.46800  3.80600   13.38600  1.000 290.51000 ? 154 TYR B N     1 
ATOM   5065 C  CA    . TYR B 2 154 ? 38.91500  5.18800   13.52200  1.000 292.55000 ? 154 TYR B CA    1 
ATOM   5066 C  C     . TYR B 2 154 ? 40.41800  5.25000   13.72600  1.000 297.22000 ? 154 TYR B C     1 
ATOM   5067 O  O     . TYR B 2 154 ? 41.12400  5.93900   12.96700  1.000 294.47000 ? 154 TYR B O     1 
ATOM   5068 C  CB    . TYR B 2 154 ? 38.16000  5.87800   14.67300  1.000 303.03000 ? 154 TYR B CB    1 
ATOM   5069 C  CG    . TYR B 2 154 ? 38.81600  7.10000   15.34000  1.000 306.99000 ? 154 TYR B CG    1 
ATOM   5070 C  CD1   . TYR B 2 154 ? 38.83900  7.22300   16.74200  1.000 301.83000 ? 154 TYR B CD1   1 
ATOM   5071 C  CD2   . TYR B 2 154 ? 39.40500  8.12500   14.58600  1.000 301.38000 ? 154 TYR B CD2   1 
ATOM   5072 C  CE1   . TYR B 2 154 ? 39.41100  8.31900   17.37600  1.000 292.39000 ? 154 TYR B CE1   1 
ATOM   5073 C  CE2   . TYR B 2 154 ? 40.01200  9.22800   15.21600  1.000 299.09000 ? 154 TYR B CE2   1 
ATOM   5074 C  CZ    . TYR B 2 154 ? 40.00400  9.31400   16.60800  1.000 295.19000 ? 154 TYR B CZ    1 
ATOM   5075 O  OH    . TYR B 2 154 ? 40.58000  10.38600  17.25200  1.000 290.91000 ? 154 TYR B OH    1 
ATOM   5076 N  N     . GLN B 2 155 ? 40.93800  4.49200   14.71000  1.000 293.40000 ? 155 GLN B N     1 
ATOM   5077 C  CA    . GLN B 2 155 ? 42.36500  4.60000   15.03300  1.000 297.03000 ? 155 GLN B CA    1 
ATOM   5078 C  C     . GLN B 2 155 ? 43.24600  4.00400   13.92900  1.000 299.33000 ? 155 GLN B C     1 
ATOM   5079 O  O     . GLN B 2 155 ? 44.37200  4.47200   13.70200  1.000 303.77000 ? 155 GLN B O     1 
ATOM   5080 C  CB    . GLN B 2 155 ? 42.66500  3.92200   16.40300  1.000 294.19000 ? 155 GLN B CB    1 
ATOM   5081 C  CG    . GLN B 2 155 ? 42.59300  4.76600   17.73400  1.000 279.63000 ? 155 GLN B CG    1 
ATOM   5082 C  CD    . GLN B 2 155 ? 41.95700  4.00600   18.90400  1.000 280.96000 ? 155 GLN B CD    1 
ATOM   5083 O  OE1   . GLN B 2 155 ? 40.73200  4.05100   19.04700  1.000 280.78000 ? 155 GLN B OE1   1 
ATOM   5084 N  NE2   . GLN B 2 155 ? 42.77400  3.37700   19.77700  1.000 283.85000 ? 155 GLN B NE2   1 
ATOM   5085 N  N     . GLN B 2 156 ? 42.76700  2.98000   13.23300  1.000 296.92000 ? 156 GLN B N     1 
ATOM   5086 C  CA    . GLN B 2 156 ? 43.62800  2.38500   12.22300  1.000 291.07000 ? 156 GLN B CA    1 
ATOM   5087 C  C     . GLN B 2 156 ? 43.37300  3.01000   10.86800  1.000 286.97000 ? 156 GLN B C     1 
ATOM   5088 O  O     . GLN B 2 156 ? 44.29300  3.23000   10.08900  1.000 284.66000 ? 156 GLN B O     1 
ATOM   5089 C  CB    . GLN B 2 156 ? 43.40600  0.85400   12.14400  1.000 286.46000 ? 156 GLN B CB    1 
ATOM   5090 C  CG    . GLN B 2 156 ? 44.29800  0.12300   13.08400  1.000 298.99000 ? 156 GLN B CG    1 
ATOM   5091 C  CD    . GLN B 2 156 ? 45.71600  0.03200   12.54900  1.000 307.27000 ? 156 GLN B CD    1 
ATOM   5092 O  OE1   . GLN B 2 156 ? 46.09000  -0.98900  11.98400  1.000 319.57000 ? 156 GLN B OE1   1 
ATOM   5093 N  NE2   . GLN B 2 156 ? 46.51000  1.09500   12.71800  1.000 309.59000 ? 156 GLN B NE2   1 
ATOM   5094 N  N     . ILE B 2 157 ? 42.13100  3.31600   10.58800  1.000 285.74000 ? 157 ILE B N     1 
ATOM   5095 C  CA    . ILE B 2 157 ? 41.73500  3.75300   9.26600   1.000 286.71000 ? 157 ILE B CA    1 
ATOM   5096 C  C     . ILE B 2 157 ? 41.92200  5.24100   9.14200   1.000 284.93000 ? 157 ILE B C     1 
ATOM   5097 O  O     . ILE B 2 157 ? 42.81200  5.70900   8.41600   1.000 285.58000 ? 157 ILE B O     1 
ATOM   5098 C  CB    . ILE B 2 157 ? 40.27300  3.41200   8.98600   1.000 293.71000 ? 157 ILE B CB    1 
ATOM   5099 C  CG1   . ILE B 2 157 ? 39.99200  1.91200   9.23300   1.000 302.75000 ? 157 ILE B CG1   1 
ATOM   5100 C  CG2   . ILE B 2 157 ? 39.90500  3.86400   7.57500   1.000 307.74000 ? 157 ILE B CG2   1 
ATOM   5101 C  CD1   . ILE B 2 157 ? 40.37200  0.97200   8.08100   1.000 320.40000 ? 157 ILE B CD1   1 
ATOM   5102 N  N     . PHE B 2 158 ? 41.04600  5.98400   9.81100   1.000 286.42000 ? 158 PHE B N     1 
ATOM   5103 C  CA    . PHE B 2 158 ? 41.03500  7.41400   9.60500   1.000 291.66000 ? 158 PHE B CA    1 
ATOM   5104 C  C     . PHE B 2 158 ? 42.40200  7.98400   9.92700   1.000 294.60000 ? 158 PHE B C     1 
ATOM   5105 O  O     . PHE B 2 158 ? 43.03400  8.63900   9.08100   1.000 297.50000 ? 158 PHE B O     1 
ATOM   5106 C  CB    . PHE B 2 158 ? 39.93700  8.02700   10.46800  1.000 289.95000 ? 158 PHE B CB    1 
ATOM   5107 C  CG    . PHE B 2 158 ? 38.53900  7.47700   10.18300  1.000 286.59000 ? 158 PHE B CG    1 
ATOM   5108 C  CD1   . PHE B 2 158 ? 38.32900  6.39800   9.34600   1.000 288.27000 ? 158 PHE B CD1   1 
ATOM   5109 C  CD2   . PHE B 2 158 ? 37.42300  8.08100   10.74100  1.000 292.86000 ? 158 PHE B CD2   1 
ATOM   5110 C  CE1   . PHE B 2 158 ? 37.07300  5.91300   9.10700   1.000 292.85000 ? 158 PHE B CE1   1 
ATOM   5111 C  CE2   . PHE B 2 158 ? 36.16600  7.61100   10.47400  1.000 290.10000 ? 158 PHE B CE2   1 
ATOM   5112 C  CZ    . PHE B 2 158 ? 35.97900  6.50600   9.65600   1.000 293.52000 ? 158 PHE B CZ    1 
ATOM   5113 N  N     . LEU B 2 159 ? 42.91600  7.64600   11.10400  1.000 293.65000 ? 159 LEU B N     1 
ATOM   5114 C  CA    . LEU B 2 159 ? 44.23500  8.07200   11.51600  1.000 296.10000 ? 159 LEU B CA    1 
ATOM   5115 C  C     . LEU B 2 159 ? 45.35800  7.32600   10.80300  1.000 292.31000 ? 159 LEU B C     1 
ATOM   5116 O  O     . LEU B 2 159 ? 46.52800  7.57200   11.12700  1.000 291.98000 ? 159 LEU B O     1 
ATOM   5117 C  CB    . LEU B 2 159 ? 44.38100  7.91900   13.03800  1.000 299.06000 ? 159 LEU B CB    1 
ATOM   5118 C  CG    . LEU B 2 159 ? 43.81000  8.90700   14.07300  1.000 291.23000 ? 159 LEU B CG    1 
ATOM   5119 C  CD1   . LEU B 2 159 ? 44.83400  9.18200   15.19200  1.000 287.93000 ? 159 LEU B CD1   1 
ATOM   5120 C  CD2   . LEU B 2 159 ? 43.32200  10.22000  13.47500  1.000 281.69000 ? 159 LEU B CD2   1 
ATOM   5121 N  N     . HIS B 2 160 ? 45.05400  6.41300   9.87000   1.000 291.47000 ? 160 HIS B N     1 
ATOM   5122 C  CA    . HIS B 2 160 ? 46.14100  5.78500   9.12100   1.000 291.37000 ? 160 HIS B CA    1 
ATOM   5123 C  C     . HIS B 2 160 ? 47.07600  6.83000   8.53500   1.000 298.46000 ? 160 HIS B C     1 
ATOM   5124 O  O     . HIS B 2 160 ? 48.30000  6.76900   8.72900   1.000 303.18000 ? 160 HIS B O     1 
ATOM   5125 C  CB    . HIS B 2 160 ? 45.60500  4.92900   7.99300   1.000 296.02000 ? 160 HIS B CB    1 
ATOM   5126 N  N     . ASP B 2 161 ? 46.49600  7.82900   7.85500   1.000 289.61000 ? 161 ASP B N     1 
ATOM   5127 C  CA    . ASP B 2 161 ? 47.27100  8.78800   7.07100   1.000 299.72000 ? 161 ASP B CA    1 
ATOM   5128 C  C     . ASP B 2 161 ? 48.33500  9.47300   7.91000   1.000 287.30000 ? 161 ASP B C     1 
ATOM   5129 O  O     . ASP B 2 161 ? 49.50900  9.54500   7.53500   1.000 285.46000 ? 161 ASP B O     1 
ATOM   5130 C  CB    . ASP B 2 161 ? 46.34200  9.84300   6.49300   1.000 288.43000 ? 161 ASP B CB    1 
ATOM   5131 N  N     . LYS B 2 162 ? 47.93500  10.00400  9.04100   1.000 293.30000 ? 162 LYS B N     1 
ATOM   5132 C  CA    . LYS B 2 162 ? 48.79100  10.86700  9.82700   1.000 291.60000 ? 162 LYS B CA    1 
ATOM   5133 C  C     . LYS B 2 162 ? 48.82900  10.31500  11.23300  1.000 294.66000 ? 162 LYS B C     1 
ATOM   5134 O  O     . LYS B 2 162 ? 47.81300  10.33500  11.93000  1.000 296.97000 ? 162 LYS B O     1 
ATOM   5135 C  CB    . LYS B 2 162 ? 48.25600  12.29300  9.81300   1.000 291.18000 ? 162 LYS B CB    1 
ATOM   5136 N  N     . GLN B 2 163 ? 49.97300  9.76500   11.61600  1.000 293.57000 ? 163 GLN B N     1 
ATOM   5137 C  CA    . GLN B 2 163 ? 50.28700  9.55100   13.02400  1.000 304.66000 ? 163 GLN B CA    1 
ATOM   5138 C  C     . GLN B 2 163 ? 51.79600  9.54300   13.15200  1.000 303.89000 ? 163 GLN B C     1 
ATOM   5139 O  O     . GLN B 2 163 ? 52.52500  9.56000   12.15800  1.000 289.09000 ? 163 GLN B O     1 
ATOM   5140 C  CB    . GLN B 2 163 ? 49.69900  8.24900   13.61000  1.000 310.54000 ? 163 GLN B CB    1 
ATOM   5141 C  CG    . GLN B 2 163 ? 48.66200  8.41000   14.80900  1.000 310.82000 ? 163 GLN B CG    1 
ATOM   5142 C  CD    . GLN B 2 163 ? 49.20400  9.04200   16.11500  1.000 308.50000 ? 163 GLN B CD    1 
ATOM   5143 O  OE1   . GLN B 2 163 ? 50.37600  8.87500   16.48600  1.000 319.53000 ? 163 GLN B OE1   1 
ATOM   5144 N  NE2   . GLN B 2 163 ? 48.32800  9.75400   16.82500  1.000 295.74000 ? 163 GLN B NE2   1 
ATOM   5145 N  N     . ALA B 2 164 ? 52.24600  9.52400   14.40200  1.000 315.10000 ? 164 ALA B N     1 
ATOM   5146 C  CA    . ALA B 2 164 ? 53.64200  9.26000   14.72000  1.000 312.06000 ? 164 ALA B CA    1 
ATOM   5147 C  C     . ALA B 2 164 ? 54.16100  8.06600   13.93500  1.000 300.29000 ? 164 ALA B C     1 
ATOM   5148 O  O     . ALA B 2 164 ? 53.66900  6.94500   14.08100  1.000 313.82000 ? 164 ALA B O     1 
ATOM   5149 C  CB    . ALA B 2 164 ? 53.79600  8.99400   16.22300  1.000 319.24000 ? 164 ALA B CB    1 
ATOM   5150 N  N     . ILE B 2 165 ? 55.16700  8.30000   13.11100  1.000 283.48000 ? 165 ILE B N     1 
ATOM   5151 C  CA    . ILE B 2 165 ? 55.78200  7.22200   12.35700  1.000 279.40000 ? 165 ILE B CA    1 
ATOM   5152 C  C     . ILE B 2 165 ? 57.21700  7.05500   12.81700  1.000 280.99000 ? 165 ILE B C     1 
ATOM   5153 O  O     . ILE B 2 165 ? 57.92300  8.03900   13.03300  1.000 281.11000 ? 165 ILE B O     1 
ATOM   5154 C  CB    . ILE B 2 165 ? 55.78400  7.49000   10.87500  1.000 276.05000 ? 165 ILE B CB    1 
ATOM   5155 N  N     . GLU B 2 166 ? 57.65700  5.81100   12.96100  1.000 277.15000 ? 166 GLU B N     1 
ATOM   5156 C  CA    . GLU B 2 166 ? 59.05900  5.56100   13.28300  1.000 272.71000 ? 166 GLU B CA    1 
ATOM   5157 C  C     . GLU B 2 166 ? 59.89500  6.19700   12.18200  1.000 276.91000 ? 166 GLU B C     1 
ATOM   5158 O  O     . GLU B 2 166 ? 60.24300  5.54200   11.20300  1.000 282.13000 ? 166 GLU B O     1 
ATOM   5159 C  CB    . GLU B 2 166 ? 59.34500  4.06600   13.41700  1.000 267.37000 ? 166 GLU B CB    1 
ATOM   5160 N  N     . LYS B 2 167 ? 60.21600  7.48100   12.34200  1.000 277.51000 ? 167 LYS B N     1 
ATOM   5161 C  CA    . LYS B 2 167 ? 61.03000  8.21600   11.38800  1.000 274.17000 ? 167 LYS B CA    1 
ATOM   5162 C  C     . LYS B 2 167 ? 62.18200  8.85200   12.13800  1.000 277.94000 ? 167 LYS B C     1 
ATOM   5163 O  O     . LYS B 2 167 ? 62.13100  9.03700   13.34700  1.000 282.87000 ? 167 LYS B O     1 
ATOM   5164 C  CB    . LYS B 2 167 ? 60.24500  9.31100   10.64900  1.000 273.17000 ? 167 LYS B CB    1 
ATOM   5165 N  N     . GLU B 2 168 ? 63.22700  9.20000   11.41500  1.000 272.81000 ? 168 GLU B N     1 
ATOM   5166 C  CA    . GLU B 2 168 ? 64.35100  9.92300   11.99100  1.000 272.47000 ? 168 GLU B CA    1 
ATOM   5167 C  C     . GLU B 2 168 ? 64.24900  11.39700  11.62300  1.000 278.36000 ? 168 GLU B C     1 
ATOM   5168 O  O     . GLU B 2 168 ? 63.88900  11.73300  10.48500  1.000 276.93000 ? 168 GLU B O     1 
ATOM   5169 C  CB    . GLU B 2 168 ? 65.68600  9.36200   11.49400  1.000 277.79000 ? 168 GLU B CB    1 
ATOM   5170 N  N     . GLU B 2 169 ? 64.55100  12.27100  12.59000  1.000 288.75000 ? 169 GLU B N     1 
ATOM   5171 C  CA    . GLU B 2 169 ? 64.57300  13.70100  12.32000  1.000 294.01000 ? 169 GLU B CA    1 
ATOM   5172 C  C     . GLU B 2 169 ? 65.44900  14.41800  13.33400  1.000 293.06000 ? 169 GLU B C     1 
ATOM   5173 O  O     . GLU B 2 169 ? 65.43000  14.10800  14.52900  1.000 291.45000 ? 169 GLU B O     1 
ATOM   5174 C  CB    . GLU B 2 169 ? 63.14800  14.29400  12.30100  1.000 301.36000 ? 169 GLU B CB    1 
ATOM   5175 C  CG    . GLU B 2 169 ? 62.98100  15.58100  11.46000  1.000 304.05000 ? 169 GLU B CG    1 
ATOM   5176 C  CD    . GLU B 2 169 ? 61.86000  15.50700  10.40000  1.000 298.67000 ? 169 GLU B CD    1 
ATOM   5177 O  OE1   . GLU B 2 169 ? 62.12800  15.89000  9.24100   1.000 296.01000 ? 169 GLU B OE1   1 
ATOM   5178 O  OE2   . GLU B 2 169 ? 60.72100  15.08600  10.71600  1.000 298.12000 ? 169 GLU B OE2   1 
ATOM   5179 N  N     . THR B 2 170 ? 66.22200  15.37100  12.83000  1.000 286.64000 ? 170 THR B N     1 
ATOM   5180 C  CA    . THR B 2 170 ? 67.07400  16.20500  13.65200  1.000 280.81000 ? 170 THR B CA    1 
ATOM   5181 C  C     . THR B 2 170 ? 66.51300  17.60000  13.71500  1.000 281.42000 ? 170 THR B C     1 
ATOM   5182 O  O     . THR B 2 170 ? 65.85900  18.08400  12.78600  1.000 284.34000 ? 170 THR B O     1 
ATOM   5183 C  CB    . THR B 2 170 ? 68.47900  16.32600  13.10700  1.000 283.83000 ? 170 THR B CB    1 
ATOM   5184 O  OG1   . THR B 2 170 ? 68.46600  17.31900  12.06800  1.000 285.75000 ? 170 THR B OG1   1 
ATOM   5185 C  CG2   . THR B 2 170 ? 68.92500  15.00200  12.56500  1.000 291.91000 ? 170 THR B CG2   1 
ATOM   5186 N  N     . TYR B 2 171 ? 66.82400  18.25200  14.80400  1.000 289.78000 ? 171 TYR B N     1 
ATOM   5187 C  CA    . TYR B 2 171 ? 66.29600  19.56000  15.08900  1.000 296.44000 ? 171 TYR B CA    1 
ATOM   5188 C  C     . TYR B 2 171 ? 67.42700  20.39500  15.67200  1.000 297.82000 ? 171 TYR B C     1 
ATOM   5189 O  O     . TYR B 2 171 ? 68.26700  19.90600  16.44100  1.000 292.48000 ? 171 TYR B O     1 
ATOM   5190 C  CB    . TYR B 2 171 ? 65.09100  19.48800  16.04400  1.000 300.01000 ? 171 TYR B CB    1 
ATOM   5191 C  CG    . TYR B 2 171 ? 64.19800  18.22200  15.95800  1.000 305.21000 ? 171 TYR B CG    1 
ATOM   5192 C  CD1   . TYR B 2 171 ? 63.41600  17.93500  14.82500  1.000 301.60000 ? 171 TYR B CD1   1 
ATOM   5193 C  CD2   . TYR B 2 171 ? 64.09400  17.34500  17.04900  1.000 306.30000 ? 171 TYR B CD2   1 
ATOM   5194 C  CE1   . TYR B 2 171 ? 62.58000  16.79200  14.78000  1.000 301.18000 ? 171 TYR B CE1   1 
ATOM   5195 C  CE2   . TYR B 2 171 ? 63.25900  16.20400  17.00800  1.000 299.85000 ? 171 TYR B CE2   1 
ATOM   5196 C  CZ    . TYR B 2 171 ? 62.50600  15.93900  15.87500  1.000 295.77000 ? 171 TYR B CZ    1 
ATOM   5197 O  OH    . TYR B 2 171 ? 61.69700  14.81800  15.84200  1.000 282.55000 ? 171 TYR B OH    1 
ATOM   5198 N  N     . ASP B 2 172 ? 67.46600  21.64700  15.26000  1.000 304.31000 ? 172 ASP B N     1 
ATOM   5199 C  CA    . ASP B 2 172 ? 68.54300  22.53200  15.64900  1.000 304.69000 ? 172 ASP B CA    1 
ATOM   5200 C  C     . ASP B 2 172 ? 68.04900  23.39600  16.79500  1.000 294.50000 ? 172 ASP B C     1 
ATOM   5201 O  O     . ASP B 2 172 ? 66.91300  23.88400  16.77500  1.000 290.24000 ? 172 ASP B O     1 
ATOM   5202 C  CB    . ASP B 2 172 ? 69.00900  23.36500  14.45000  1.000 314.38000 ? 172 ASP B CB    1 
ATOM   5203 C  CG    . ASP B 2 172 ? 69.70000  22.51100  13.37600  1.000 312.82000 ? 172 ASP B CG    1 
ATOM   5204 O  OD1   . ASP B 2 172 ? 69.86100  21.29000  13.60400  1.000 303.68000 ? 172 ASP B OD1   1 
ATOM   5205 O  OD2   . ASP B 2 172 ? 70.06000  23.06300  12.31000  1.000 317.83000 ? 172 ASP B OD2   1 
ATOM   5206 N  N     . SER B 2 173 ? 68.87600  23.53100  17.81700  1.000 294.77000 ? 173 SER B N     1 
ATOM   5207 C  CA    . SER B 2 173 ? 68.45900  24.33600  18.94100  1.000 290.59000 ? 173 SER B CA    1 
ATOM   5208 C  C     . SER B 2 173 ? 68.48500  25.81300  18.56200  1.000 287.89000 ? 173 SER B C     1 
ATOM   5209 O  O     . SER B 2 173 ? 68.67500  26.18600  17.40200  1.000 287.04000 ? 173 SER B O     1 
ATOM   5210 C  CB    . SER B 2 173 ? 69.35600  24.04400  20.13500  1.000 295.95000 ? 173 SER B CB    1 
ATOM   5211 O  OG    . SER B 2 173 ? 69.40600  25.16600  20.97300  1.000 297.37000 ? 173 SER B OG    1 
ATOM   5212 N  N     . ASN B 2 174 ? 68.22200  26.65100  19.55300  1.000 290.47000 ? 174 ASN B N     1 
ATOM   5213 C  CA    . ASN B 2 174 ? 68.60800  28.04600  19.51900  1.000 293.46000 ? 174 ASN B CA    1 
ATOM   5214 C  C     . ASN B 2 174 ? 69.64500  28.32500  20.59100  1.000 296.50000 ? 174 ASN B C     1 
ATOM   5215 O  O     . ASN B 2 174 ? 70.02300  29.48300  20.81900  1.000 296.24000 ? 174 ASN B O     1 
ATOM   5216 C  CB    . ASN B 2 174 ? 67.37900  28.92400  19.69800  1.000 294.68000 ? 174 ASN B CB    1 
ATOM   5217 C  CG    . ASN B 2 174 ? 66.87500  28.93300  21.11400  1.000 294.00000 ? 174 ASN B CG    1 
ATOM   5218 O  OD1   . ASN B 2 174 ? 66.80600  27.89600  21.76900  1.000 291.69000 ? 174 ASN B OD1   1 
ATOM   5219 N  ND2   . ASN B 2 174 ? 66.57900  30.11900  21.62400  1.000 296.83000 ? 174 ASN B ND2   1 
ATOM   5220 N  N     . TRP B 2 175 ? 70.05300  27.27100  21.30500  1.000 294.77000 ? 175 TRP B N     1 
ATOM   5221 C  CA    . TRP B 2 175 ? 71.21900  27.29700  22.18000  1.000 297.88000 ? 175 TRP B CA    1 
ATOM   5222 C  C     . TRP B 2 175 ? 72.46200  27.05400  21.30100  1.000 294.90000 ? 175 TRP B C     1 
ATOM   5223 O  O     . TRP B 2 175 ? 72.47400  26.18900  20.42400  1.000 288.60000 ? 175 TRP B O     1 
ATOM   5224 C  CB    . TRP B 2 175 ? 71.13600  26.25500  23.28000  1.000 297.06000 ? 175 TRP B CB    1 
ATOM   5225 C  CG    . TRP B 2 175 ? 70.05500  26.39500  24.20600  1.000 294.69000 ? 175 TRP B CG    1 
ATOM   5226 C  CD1   . TRP B 2 175 ? 69.16600  27.39000  24.25400  1.000 295.51000 ? 175 TRP B CD1   1 
ATOM   5227 C  CD2   . TRP B 2 175 ? 69.74900  25.48700  25.26600  1.000 290.81000 ? 175 TRP B CD2   1 
ATOM   5228 N  NE1   . TRP B 2 175 ? 68.30400  27.17400  25.28700  1.000 294.67000 ? 175 TRP B NE1   1 
ATOM   5229 C  CE2   . TRP B 2 175 ? 68.64300  26.00700  25.92600  1.000 292.60000 ? 175 TRP B CE2   1 
ATOM   5230 C  CE3   . TRP B 2 175 ? 70.31200  24.28100  25.71100  1.000 291.38000 ? 175 TRP B CE3   1 
ATOM   5231 C  CZ2   . TRP B 2 175 ? 68.07700  25.38800  27.00400  1.000 297.43000 ? 175 TRP B CZ2   1 
ATOM   5232 C  CZ3   . TRP B 2 175 ? 69.73900  23.65100  26.79800  1.000 297.96000 ? 175 TRP B CZ3   1 
ATOM   5233 C  CH2   . TRP B 2 175 ? 68.61900  24.21900  27.43100  1.000 302.82000 ? 175 TRP B CH2   1 
ATOM   5234 N  N     . PHE B 2 176 ? 73.48000  27.87400  21.49500  1.000 302.34000 ? 176 PHE B N     1 
ATOM   5235 C  CA    . PHE B 2 176 ? 74.73300  28.00600  20.73600  1.000 303.86000 ? 176 PHE B CA    1 
ATOM   5236 C  C     . PHE B 2 176 ? 75.85500  27.84900  21.73600  1.000 307.63000 ? 176 PHE B C     1 
ATOM   5237 O  O     . PHE B 2 176 ? 76.19800  28.82700  22.47900  1.000 307.30000 ? 176 PHE B O     1 
ATOM   5238 C  CB    . PHE B 2 176 ? 74.85400  29.32800  19.97400  1.000 303.57000 ? 176 PHE B CB    1 
ATOM   5239 C  CG    . PHE B 2 176 ? 73.77900  29.42400  18.84900  1.000 304.75000 ? 176 PHE B CG    1 
ATOM   5240 C  CD1   . PHE B 2 176 ? 74.05100  29.23400  17.53800  1.000 309.88000 ? 176 PHE B CD1   1 
ATOM   5241 C  CD2   . PHE B 2 176 ? 72.44200  29.67200  19.21400  1.000 302.35000 ? 176 PHE B CD2   1 
ATOM   5242 C  CE1   . PHE B 2 176 ? 72.84700  29.26600  16.68800  1.000 310.87000 ? 176 PHE B CE1   1 
ATOM   5243 C  CE2   . PHE B 2 176 ? 71.39200  29.76200  18.36000  1.000 304.36000 ? 176 PHE B CE2   1 
ATOM   5244 C  CZ    . PHE B 2 176 ? 71.59400  29.60300  17.12200  1.000 308.31000 ? 176 PHE B CZ    1 
ATOM   5245 N  N     . PRO B 2 177 ? 76.41000  26.63100  21.84000  1.000 309.46000 ? 177 PRO B N     1 
ATOM   5246 C  CA    . PRO B 2 177 ? 77.33500  26.33000  22.94400  1.000 312.97000 ? 177 PRO B CA    1 
ATOM   5247 C  C     . PRO B 2 177 ? 78.56200  27.20900  22.88300  1.000 317.83000 ? 177 PRO B C     1 
ATOM   5248 O  O     . PRO B 2 177 ? 79.12600  27.43400  21.81500  1.000 321.91000 ? 177 PRO B O     1 
ATOM   5249 C  CB    . PRO B 2 177 ? 77.72100  24.86700  22.72300  1.000 310.12000 ? 177 PRO B CB    1 
ATOM   5250 C  CG    . PRO B 2 177 ? 77.49400  24.69000  21.23400  1.000 303.12000 ? 177 PRO B CG    1 
ATOM   5251 C  CD    . PRO B 2 177 ? 76.36700  25.55300  20.81700  1.000 301.53000 ? 177 PRO B CD    1 
ATOM   5252 N  N     . ILE B 2 178 ? 78.86100  27.85500  24.00300  1.000 316.04000 ? 178 ILE B N     1 
ATOM   5253 C  CA    . ILE B 2 178 ? 80.19000  28.42300  24.18600  1.000 322.29000 ? 178 ILE B CA    1 
ATOM   5254 C  C     . ILE B 2 178 ? 81.24500  27.35000  23.86500  1.000 320.42000 ? 178 ILE B C     1 
ATOM   5255 O  O     . ILE B 2 178 ? 81.06200  26.15500  24.16000  1.000 316.08000 ? 178 ILE B O     1 
ATOM   5256 C  CB    . ILE B 2 178 ? 80.27300  28.99500  25.62000  1.000 326.17000 ? 178 ILE B CB    1 
ATOM   5257 C  CG1   . ILE B 2 178 ? 78.86900  29.46300  26.09700  1.000 315.21000 ? 178 ILE B CG1   1 
ATOM   5258 C  CG2   . ILE B 2 178 ? 81.32900  30.02200  25.75600  1.000 335.65000 ? 178 ILE B CG2   1 
ATOM   5259 C  CD1   . ILE B 2 178 ? 78.49100  30.92100  25.88500  1.000 306.49000 ? 178 ILE B CD1   1 
ATOM   5260 N  N     . ILE B 2 179 ? 82.33500  27.76000  23.22000  1.000 309.43000 ? 179 ILE B N     1 
ATOM   5261 C  CA    . ILE B 2 179 ? 83.40600  26.85900  22.84700  1.000 308.63000 ? 179 ILE B CA    1 
ATOM   5262 C  C     . ILE B 2 179 ? 84.55600  26.97700  23.81600  1.000 311.42000 ? 179 ILE B C     1 
ATOM   5263 O  O     . ILE B 2 179 ? 84.98600  25.98000  24.37800  1.000 319.05000 ? 179 ILE B O     1 
ATOM   5264 C  CB    . ILE B 2 179 ? 83.87600  27.13200  21.40200  1.000 313.41000 ? 179 ILE B CB    1 
ATOM   5265 C  CG1   . ILE B 2 179 ? 82.82500  26.72900  20.40500  1.000 305.07000 ? 179 ILE B CG1   1 
ATOM   5266 C  CG2   . ILE B 2 179 ? 85.19000  26.34200  21.10900  1.000 313.26000 ? 179 ILE B CG2   1 
ATOM   5267 C  CD1   . ILE B 2 179 ? 83.18400  27.17600  19.01200  1.000 304.67000 ? 179 ILE B CD1   1 
ATOM   5268 N  N     . SER B 2 180 ? 85.11000  28.18800  23.99200  1.000 316.06000 ? 180 SER B N     1 
ATOM   5269 C  CA    . SER B 2 180 ? 86.33500  28.41000  24.76800  1.000 315.54000 ? 180 SER B CA    1 
ATOM   5270 C  C     . SER B 2 180 ? 86.15200  29.53500  25.78100  1.000 320.23000 ? 180 SER B C     1 
ATOM   5271 O  O     . SER B 2 180 ? 85.73800  30.63500  25.41100  1.000 318.50000 ? 180 SER B O     1 
ATOM   5272 C  CB    . SER B 2 180 ? 87.49700  28.76800  23.84100  1.000 313.66000 ? 180 SER B CB    1 
ATOM   5273 O  OG    . SER B 2 180 ? 87.21500  29.94100  23.07900  1.000 319.36000 ? 180 SER B OG    1 
ATOM   5274 N  N     . PHE B 2 181 ? 86.52400  29.27600  27.03800  1.000 339.93000 ? 181 PHE B N     1 
ATOM   5275 C  CA    . PHE B 2 181 ? 86.47900  30.22500  28.13400  1.000 345.32000 ? 181 PHE B CA    1 
ATOM   5276 C  C     . PHE B 2 181 ? 87.88900  30.61700  28.59300  1.000 359.22000 ? 181 PHE B C     1 
ATOM   5277 O  O     . PHE B 2 181 ? 88.82200  29.78500  28.56000  1.000 356.32000 ? 181 PHE B O     1 
ATOM   5278 C  CB    . PHE B 2 181 ? 85.68400  29.66200  29.34000  1.000 346.19000 ? 181 PHE B CB    1 
ATOM   5279 C  CG    . PHE B 2 181 ? 84.23100  30.20100  29.48400  1.000 348.31000 ? 181 PHE B CG    1 
ATOM   5280 C  CD1   . PHE B 2 181 ? 83.95000  31.52900  29.83300  1.000 354.27000 ? 181 PHE B CD1   1 
ATOM   5281 C  CD2   . PHE B 2 181 ? 83.15800  29.33700  29.32500  1.000 349.49000 ? 181 PHE B CD2   1 
ATOM   5282 C  CE1   . PHE B 2 181 ? 82.60300  31.98800  29.97900  1.000 347.27000 ? 181 PHE B CE1   1 
ATOM   5283 C  CE2   . PHE B 2 181 ? 81.83500  29.78100  29.47000  1.000 349.78000 ? 181 PHE B CE2   1 
ATOM   5284 C  CZ    . PHE B 2 181 ? 81.55200  31.10600  29.79700  1.000 343.41000 ? 181 PHE B CZ    1 
ATOM   5285 N  N     . PRO B 2 182 ? 88.06300  31.88300  29.03700  1.000 368.31000 ? 182 PRO B N     1 
ATOM   5286 C  CA    . PRO B 2 182 ? 89.37700  32.34300  29.54500  1.000 370.09000 ? 182 PRO B CA    1 
ATOM   5287 C  C     . PRO B 2 182 ? 89.94600  31.47100  30.65700  1.000 370.16000 ? 182 PRO B C     1 
ATOM   5288 O  O     . PRO B 2 182 ? 89.25200  31.15300  31.62600  1.000 373.72000 ? 182 PRO B O     1 
ATOM   5289 C  CB    . PRO B 2 182 ? 89.09000  33.75700  30.06700  1.000 364.13000 ? 182 PRO B CB    1 
ATOM   5290 C  CG    . PRO B 2 182 ? 87.96800  34.23300  29.19400  1.000 361.98000 ? 182 PRO B CG    1 
ATOM   5291 C  CD    . PRO B 2 182 ? 87.11100  33.00600  28.87000  1.000 365.67000 ? 182 PRO B CD    1 
ATOM   5292 N  N     . ASN B 2 183 ? 91.23200  31.10200  30.51000  1.000 354.69000 ? 183 ASN B N     1 
ATOM   5293 C  CA    . ASN B 2 183 ? 91.81700  30.03900  31.33300  1.000 352.94000 ? 183 ASN B CA    1 
ATOM   5294 C  C     . ASN B 2 183 ? 91.53200  30.23000  32.81800  1.000 360.57000 ? 183 ASN B C     1 
ATOM   5295 O  O     . ASN B 2 183 ? 91.29300  29.25600  33.54800  1.000 361.28000 ? 183 ASN B O     1 
ATOM   5296 C  CB    . ASN B 2 183 ? 93.31300  29.96100  31.05000  1.000 344.92000 ? 183 ASN B CB    1 
ATOM   5297 C  CG    . ASN B 2 183 ? 93.58100  29.63500  29.59900  1.000 341.68000 ? 183 ASN B CG    1 
ATOM   5298 O  OD1   . ASN B 2 183 ? 92.74800  29.00200  28.95500  1.000 344.67000 ? 183 ASN B OD1   1 
ATOM   5299 N  ND2   . ASN B 2 183 ? 94.70700  30.08700  29.06600  1.000 334.98000 ? 183 ASN B ND2   1 
ATOM   5300 N  N     . GLU B 2 184 ? 91.49400  31.47900  33.26600  1.000 365.02000 ? 184 GLU B N     1 
ATOM   5301 C  CA    . GLU B 2 184 ? 91.14300  31.82900  34.62900  1.000 364.78000 ? 184 GLU B CA    1 
ATOM   5302 C  C     . GLU B 2 184 ? 90.03500  32.86600  34.61300  1.000 363.33000 ? 184 GLU B C     1 
ATOM   5303 O  O     . GLU B 2 184 ? 89.80400  33.54900  33.61500  1.000 361.20000 ? 184 GLU B O     1 
ATOM   5304 C  CB    . GLU B 2 184 ? 92.33900  32.40300  35.39000  1.000 376.18000 ? 184 GLU B CB    1 
ATOM   5305 C  CG    . GLU B 2 184 ? 93.63700  31.75600  35.01700  1.000 381.47000 ? 184 GLU B CG    1 
ATOM   5306 C  CD    . GLU B 2 184 ? 94.82000  32.49200  35.58800  1.000 385.12000 ? 184 GLU B CD    1 
ATOM   5307 O  OE1   . GLU B 2 184 ? 94.71800  32.98000  36.73300  1.000 381.25000 ? 184 GLU B OE1   1 
ATOM   5308 O  OE2   . GLU B 2 184 ? 95.84900  32.58900  34.88700  1.000 396.08000 ? 184 GLU B OE2   1 
ATOM   5309 N  N     . LEU B 2 185 ? 89.35300  32.97800  35.73300  1.000 356.35000 ? 185 LEU B N     1 
ATOM   5310 C  CA    . LEU B 2 185 ? 88.58000  34.16400  36.05700  1.000 360.63000 ? 185 LEU B CA    1 
ATOM   5311 C  C     . LEU B 2 185 ? 89.28800  34.83200  37.22300  1.000 370.56000 ? 185 LEU B C     1 
ATOM   5312 O  O     . LEU B 2 185 ? 89.49300  34.19900  38.25900  1.000 373.22000 ? 185 LEU B O     1 
ATOM   5313 C  CB    . LEU B 2 185 ? 87.13900  33.80600  36.42100  1.000 360.37000 ? 185 LEU B CB    1 
ATOM   5314 C  CG    . LEU B 2 185 ? 86.37700  34.87400  37.20400  1.000 362.97000 ? 185 LEU B CG    1 
ATOM   5315 C  CD1   . LEU B 2 185 ? 86.35400  36.16700  36.44900  1.000 353.23000 ? 185 LEU B CD1   1 
ATOM   5316 C  CD2   . LEU B 2 185 ? 84.95800  34.41500  37.50800  1.000 362.40000 ? 185 LEU B CD2   1 
ATOM   5317 N  N     . ARG B 2 186 ? 89.67700  36.08800  37.06800  1.000 374.16000 ? 186 ARG B N     1 
ATOM   5318 C  CA    . ARG B 2 186 ? 90.32500  36.77900  38.16900  1.000 375.68000 ? 186 ARG B CA    1 
ATOM   5319 C  C     . ARG B 2 186 ? 89.47800  37.93900  38.67900  1.000 375.34000 ? 186 ARG B C     1 
ATOM   5320 O  O     . ARG B 2 186 ? 88.66500  38.52600  37.93700  1.000 361.46000 ? 186 ARG B O     1 
ATOM   5321 C  CB    . ARG B 2 186 ? 91.69600  37.27200  37.74800  1.000 377.83000 ? 186 ARG B CB    1 
ATOM   5322 C  CG    . ARG B 2 186 ? 91.60000  38.11000  36.53400  1.000 378.43000 ? 186 ARG B CG    1 
ATOM   5323 C  CD    . ARG B 2 186 ? 92.59600  37.65700  35.50700  1.000 375.90000 ? 186 ARG B CD    1 
ATOM   5324 N  NE    . ARG B 2 186 ? 92.23900  36.39600  34.86100  1.000 373.49000 ? 186 ARG B NE    1 
ATOM   5325 C  CZ    . ARG B 2 186 ? 91.31400  36.28600  33.91400  1.000 367.80000 ? 186 ARG B CZ    1 
ATOM   5326 N  NH1   . ARG B 2 186 ? 90.62800  37.34600  33.52100  1.000 368.93000 ? 186 ARG B NH1   1 
ATOM   5327 N  NH2   . ARG B 2 186 ? 91.07400  35.12200  33.35300  1.000 362.99000 ? 186 ARG B NH2   1 
ATOM   5328 N  N     . PHE B 2 187 ? 89.74600  38.27400  39.96000  1.000 400.50000 ? 187 PHE B N     1 
ATOM   5329 C  CA    . PHE B 2 187 ? 88.99100  39.23400  40.77000  1.000 404.65000 ? 187 PHE B CA    1 
ATOM   5330 C  C     . PHE B 2 187 ? 89.94200  40.28600  41.34200  1.000 405.49000 ? 187 PHE B C     1 
ATOM   5331 O  O     . PHE B 2 187 ? 90.76800  39.96000  42.20600  1.000 403.76000 ? 187 PHE B O     1 
ATOM   5332 C  CB    . PHE B 2 187 ? 88.27000  38.62400  41.96400  1.000 403.60000 ? 187 PHE B CB    1 
ATOM   5333 C  CG    . PHE B 2 187 ? 87.11500  37.71800  41.61700  1.000 409.13000 ? 187 PHE B CG    1 
ATOM   5334 C  CD1   . PHE B 2 187 ? 86.56200  37.67800  40.33100  1.000 402.99000 ? 187 PHE B CD1   1 
ATOM   5335 C  CD2   . PHE B 2 187 ? 86.57000  36.89900  42.58700  1.000 403.15000 ? 187 PHE B CD2   1 
ATOM   5336 C  CE1   . PHE B 2 187 ? 85.47400  36.80600  40.05400  1.000 407.23000 ? 187 PHE B CE1   1 
ATOM   5337 C  CE2   . PHE B 2 187 ? 85.49600  36.02800  42.34000  1.000 400.01000 ? 187 PHE B CE2   1 
ATOM   5338 C  CZ    . PHE B 2 187 ? 84.94400  35.98700  41.04000  1.000 412.47000 ? 187 PHE B CZ    1 
ATOM   5339 N  N     . HIS B 2 188 ? 89.74500  41.56400  40.97500  1.000 399.78000 ? 188 HIS B N     1 
ATOM   5340 C  CA    . HIS B 2 188 ? 90.72300  42.58000  41.29100  1.000 396.47000 ? 188 HIS B CA    1 
ATOM   5341 C  C     . HIS B 2 188 ? 90.32000  43.37700  42.51300  1.000 394.89000 ? 188 HIS B C     1 
ATOM   5342 O  O     . HIS B 2 188 ? 89.29500  44.05600  42.50600  1.000 392.58000 ? 188 HIS B O     1 
ATOM   5343 C  CB    . HIS B 2 188 ? 90.98100  43.43400  40.09300  1.000 387.03000 ? 188 HIS B CB    1 
ATOM   5344 C  CG    . HIS B 2 188 ? 91.23300  42.65000  38.84700  1.000 385.48000 ? 188 HIS B CG    1 
ATOM   5345 N  ND1   . HIS B 2 188 ? 92.21100  41.68300  38.73800  1.000 385.72000 ? 188 HIS B ND1   1 
ATOM   5346 C  CD2   . HIS B 2 188 ? 90.60200  42.67400  37.65100  1.000 375.18000 ? 188 HIS B CD2   1 
ATOM   5347 C  CE1   . HIS B 2 188 ? 92.20400  41.17400  37.51800  1.000 379.55000 ? 188 HIS B CE1   1 
ATOM   5348 N  NE2   . HIS B 2 188 ? 91.23400  41.75800  36.83800  1.000 376.00000 ? 188 HIS B NE2   1 
ATOM   5349 N  N     . ARG B 2 189 ? 91.14500  43.26500  43.56700  1.000 396.84000 ? 189 ARG B N     1 
ATOM   5350 C  CA    . ARG B 2 189 ? 91.12300  44.15100  44.72400  1.000 393.38000 ? 189 ARG B CA    1 
ATOM   5351 C  C     . ARG B 2 189 ? 91.55700  45.52900  44.24900  1.000 398.31000 ? 189 ARG B C     1 
ATOM   5352 O  O     . ARG B 2 189 ? 92.53600  46.09500  44.73300  1.000 400.79000 ? 189 ARG B O     1 
ATOM   5353 C  CB    . ARG B 2 189 ? 92.04000  43.60900  45.80000  1.000 391.01000 ? 189 ARG B CB    1 
ATOM   5354 C  CG    . ARG B 2 189 ? 91.37800  43.54000  47.17300  1.000 378.68000 ? 189 ARG B CG    1 
ATOM   5355 C  CD    . ARG B 2 189 ? 91.46200  42.11100  47.68500  1.000 375.34000 ? 189 ARG B CD    1 
ATOM   5356 N  NE    . ARG B 2 189 ? 92.82500  41.67900  47.99200  1.000 372.43000 ? 189 ARG B NE    1 
ATOM   5357 C  CZ    . ARG B 2 189 ? 93.12300  40.63100  48.76000  1.000 367.43000 ? 189 ARG B CZ    1 
ATOM   5358 N  NH1   . ARG B 2 189 ? 92.15600  39.90300  49.32100  1.000 365.24000 ? 189 ARG B NH1   1 
ATOM   5359 N  NH2   . ARG B 2 189 ? 94.39400  40.31600  48.97900  1.000 362.56000 ? 189 ARG B NH2   1 
ATOM   5360 N  N     . TYR B 2 190 ? 90.74100  46.08400  43.34000  1.000 397.45000 ? 190 TYR B N     1 
ATOM   5361 C  CA    . TYR B 2 190 ? 91.02700  47.37100  42.71500  1.000 394.86000 ? 190 TYR B CA    1 
ATOM   5362 C  C     . TYR B 2 190 ? 91.28000  48.46900  43.74000  1.000 394.50000 ? 190 TYR B C     1 
ATOM   5363 O  O     . TYR B 2 190 ? 92.21600  49.26700  43.59900  1.000 389.08000 ? 190 TYR B O     1 
ATOM   5364 C  CB    . TYR B 2 190 ? 89.85100  47.72800  41.82600  1.000 389.72000 ? 190 TYR B CB    1 
ATOM   5365 C  CG    . TYR B 2 190 ? 90.22500  47.63200  40.40300  1.000 388.04000 ? 190 TYR B CG    1 
ATOM   5366 C  CD1   . TYR B 2 190 ? 91.06400  46.62300  39.96000  1.000 388.24000 ? 190 TYR B CD1   1 
ATOM   5367 C  CD2   . TYR B 2 190 ? 89.79400  48.56200  39.50700  1.000 388.31000 ? 190 TYR B CD2   1 
ATOM   5368 C  CE1   . TYR B 2 190 ? 91.44400  46.53200  38.65500  1.000 386.14000 ? 190 TYR B CE1   1 
ATOM   5369 C  CE2   . TYR B 2 190 ? 90.17200  48.48100  38.20400  1.000 392.52000 ? 190 TYR B CE2   1 
ATOM   5370 C  CZ    . TYR B 2 190 ? 90.99200  47.47700  37.77100  1.000 390.02000 ? 190 TYR B CZ    1 
ATOM   5371 O  OH    . TYR B 2 190 ? 91.35300  47.43600  36.43400  1.000 391.60000 ? 190 TYR B OH    1 
ATOM   5372 N  N     . ASP B 2 191 ? 90.43800  48.52900  44.77000  1.000 399.39000 ? 191 ASP B N     1 
ATOM   5373 C  CA    . ASP B 2 191 ? 90.59200  49.40800  45.93700  1.000 395.66000 ? 191 ASP B CA    1 
ATOM   5374 C  C     . ASP B 2 191 ? 90.58200  50.88200  45.44200  1.000 396.44000 ? 191 ASP B C     1 
ATOM   5375 O  O     . ASP B 2 191 ? 89.64800  51.25800  44.76900  1.000 403.43000 ? 191 ASP B O     1 
ATOM   5376 C  CB    . ASP B 2 191 ? 91.79600  48.94600  46.74800  1.000 388.42000 ? 191 ASP B CB    1 
ATOM   5377 C  CG    . ASP B 2 191 ? 91.38800  48.01000  47.88300  1.000 382.34000 ? 191 ASP B CG    1 
ATOM   5378 O  OD1   . ASP B 2 191 ? 90.19500  48.00300  48.22800  1.000 377.65000 ? 191 ASP B OD1   1 
ATOM   5379 O  OD2   . ASP B 2 191 ? 92.25300  47.29500  48.45800  1.000 379.93000 ? 191 ASP B OD2   1 
ATOM   5380 N  N     . TRP B 2 192 ? 91.62900  51.66300  45.76100  1.000 398.13000 ? 192 TRP B N     1 
ATOM   5381 C  CA    . TRP B 2 192 ? 91.53200  53.10400  45.49800  1.000 405.46000 ? 192 TRP B CA    1 
ATOM   5382 C  C     . TRP B 2 192 ? 91.26300  53.37900  44.03700  1.000 402.67000 ? 192 TRP B C     1 
ATOM   5383 O  O     . TRP B 2 192 ? 90.61900  54.38700  43.70000  1.000 402.57000 ? 192 TRP B O     1 
ATOM   5384 C  CB    . TRP B 2 192 ? 92.80300  53.83300  45.98900  1.000 402.94000 ? 192 TRP B CB    1 
ATOM   5385 C  CG    . TRP B 2 192 ? 94.06700  53.85100  45.11400  1.000 413.01000 ? 192 TRP B CG    1 
ATOM   5386 C  CD1   . TRP B 2 192 ? 94.15800  54.06800  43.75600  1.000 413.55000 ? 192 TRP B CD1   1 
ATOM   5387 C  CD2   . TRP B 2 192 ? 95.42000  53.70500  45.57400  1.000 415.12000 ? 192 TRP B CD2   1 
ATOM   5388 N  NE1   . TRP B 2 192 ? 95.47200  54.02700  43.35100  1.000 413.39000 ? 192 TRP B NE1   1 
ATOM   5389 C  CE2   . TRP B 2 192 ? 96.26600  53.81000  44.44700  1.000 412.58000 ? 192 TRP B CE2   1 
ATOM   5390 C  CE3   . TRP B 2 192 ? 96.00000  53.47900  46.82900  1.000 412.07000 ? 192 TRP B CE3   1 
ATOM   5391 C  CZ2   . TRP B 2 192 ? 97.65600  53.70600  44.54700  1.000 406.45000 ? 192 TRP B CZ2   1 
ATOM   5392 C  CZ3   . TRP B 2 192 ? 97.37700  53.36800  46.91800  1.000 403.31000 ? 192 TRP B CZ3   1 
ATOM   5393 C  CH2   . TRP B 2 192 ? 98.18700  53.47600  45.78700  1.000 404.42000 ? 192 TRP B CH2   1 
ATOM   5394 N  N     . ARG B 2 193 ? 91.70500  52.46700  43.15900  1.000 393.56000 ? 193 ARG B N     1 
ATOM   5395 C  CA    . ARG B 2 193 ? 91.49100  52.66500  41.73400  1.000 390.20000 ? 193 ARG B CA    1 
ATOM   5396 C  C     . ARG B 2 193 ? 90.01400  52.56500  41.37200  1.000 383.29000 ? 193 ARG B C     1 
ATOM   5397 O  O     . ARG B 2 193 ? 89.53600  53.31400  40.51300  1.000 378.78000 ? 193 ARG B O     1 
ATOM   5398 C  CB    . ARG B 2 193 ? 92.32600  51.66700  40.91700  1.000 383.52000 ? 193 ARG B CB    1 
ATOM   5399 N  N     . LEU B 2 194 ? 89.28700  51.63100  41.98000  1.000 374.10000 ? 194 LEU B N     1 
ATOM   5400 C  CA    . LEU B 2 194 ? 87.87100  51.52800  41.70000  1.000 374.08000 ? 194 LEU B CA    1 
ATOM   5401 C  C     . LEU B 2 194 ? 87.16100  52.76000  42.22300  1.000 373.21000 ? 194 LEU B C     1 
ATOM   5402 O  O     . LEU B 2 194 ? 87.52000  53.26200  43.28100  1.000 376.17000 ? 194 LEU B O     1 
ATOM   5403 C  CB    . LEU B 2 194 ? 87.28800  50.25900  42.30000  1.000 373.93000 ? 194 LEU B CB    1 
ATOM   5404 C  CG    . LEU B 2 194 ? 86.78100  50.12800  43.72700  1.000 369.30000 ? 194 LEU B CG    1 
ATOM   5405 C  CD1   . LEU B 2 194 ? 85.27400  50.39100  43.77000  1.000 361.66000 ? 194 LEU B CD1   1 
ATOM   5406 C  CD2   . LEU B 2 194 ? 87.11500  48.74400  44.26900  1.000 373.12000 ? 194 LEU B CD2   1 
ATOM   5407 N  N     . PRO B 2 195 ? 86.29900  53.34700  41.45800  1.000 355.31000 ? 195 PRO B N     1 
ATOM   5408 C  CA    . PRO B 2 195 ? 85.30600  54.26600  42.01600  1.000 349.32000 ? 195 PRO B CA    1 
ATOM   5409 C  C     . PRO B 2 195 ? 83.93200  53.65300  41.91000  1.000 348.52000 ? 195 PRO B C     1 
ATOM   5410 O  O     . PRO B 2 195 ? 83.50600  53.28000  40.82200  1.000 349.46000 ? 195 PRO B O     1 
ATOM   5411 C  CB    . PRO B 2 195 ? 85.45500  55.53400  41.15600  1.000 338.69000 ? 195 PRO B CB    1 
ATOM   5412 C  CG    . PRO B 2 195 ? 85.90500  55.00500  39.88000  1.000 333.90000 ? 195 PRO B CG    1 
ATOM   5413 C  CD    . PRO B 2 195 ? 86.60000  53.65600  40.06200  1.000 344.54000 ? 195 PRO B CD    1 
ATOM   5414 N  N     . LYS B 2 196 ? 83.25900  53.47900  43.04300  1.000 361.63000 ? 196 LYS B N     1 
ATOM   5415 C  CA    . LYS B 2 196 ? 81.92400  52.88000  43.02100  1.000 362.62000 ? 196 LYS B CA    1 
ATOM   5416 C  C     . LYS B 2 196 ? 80.93100  53.75200  42.24900  1.000 356.13000 ? 196 LYS B C     1 
ATOM   5417 O  O     . LYS B 2 196 ? 80.06800  53.23700  41.52200  1.000 359.92000 ? 196 LYS B O     1 
ATOM   5418 C  CB    . LYS B 2 196 ? 81.42900  52.63000  44.45800  1.000 379.21000 ? 196 LYS B CB    1 
ATOM   5419 C  CG    . LYS B 2 196 ? 82.18000  53.43400  45.54000  1.000 375.10000 ? 196 LYS B CG    1 
ATOM   5420 C  CD    . LYS B 2 196 ? 81.83600  53.09700  47.02500  1.000 346.29000 ? 196 LYS B CD    1 
ATOM   5421 C  CE    . LYS B 2 196 ? 82.02700  51.62400  47.42200  1.000 347.38000 ? 196 LYS B CE    1 
ATOM   5422 N  NZ    . LYS B 2 196 ? 83.32900  51.01200  47.05500  1.000 354.20000 ? 196 LYS B NZ    1 
ATOM   5423 N  N     . GLN B 2 197 ? 81.05000  55.07800  42.36800  1.000 357.38000 ? 197 GLN B N     1 
ATOM   5424 C  CA    . GLN B 2 197 ? 80.09400  55.93700  41.68100  1.000 354.78000 ? 197 GLN B CA    1 
ATOM   5425 C  C     . GLN B 2 197 ? 80.13600  55.75200  40.16800  1.000 355.98000 ? 197 GLN B C     1 
ATOM   5426 O  O     . GLN B 2 197 ? 79.10200  55.93500  39.50600  1.000 364.60000 ? 197 GLN B O     1 
ATOM   5427 C  CB    . GLN B 2 197 ? 80.33700  57.39300  42.07000  1.000 343.88000 ? 197 GLN B CB    1 
ATOM   5428 C  CG    . GLN B 2 197 ? 80.88400  58.27900  40.98300  1.000 338.81000 ? 197 GLN B CG    1 
ATOM   5429 C  CD    . GLN B 2 197 ? 79.77700  58.96500  40.22300  1.000 343.23000 ? 197 GLN B CD    1 
ATOM   5430 O  OE1   . GLN B 2 197 ? 79.12700  59.87900  40.74100  1.000 340.43000 ? 197 GLN B OE1   1 
ATOM   5431 N  NE2   . GLN B 2 197 ? 79.54000  58.52200  38.99100  1.000 354.70000 ? 197 GLN B NE2   1 
ATOM   5432 N  N     . PHE B 2 198 ? 81.28100  55.34200  39.61800  1.000 365.88000 ? 198 PHE B N     1 
ATOM   5433 C  CA    . PHE B 2 198 ? 81.43000  55.22000  38.17400  1.000 367.50000 ? 198 PHE B CA    1 
ATOM   5434 C  C     . PHE B 2 198 ? 80.67000  54.01500  37.64100  1.000 362.62000 ? 198 PHE B C     1 
ATOM   5435 O  O     . PHE B 2 198 ? 80.49600  53.00000  38.31600  1.000 371.15000 ? 198 PHE B O     1 
ATOM   5436 C  CB    . PHE B 2 198 ? 82.90200  55.09100  37.76100  1.000 366.48000 ? 198 PHE B CB    1 
ATOM   5437 C  CG    . PHE B 2 198 ? 83.15700  55.30900  36.26800  1.000 360.79000 ? 198 PHE B CG    1 
ATOM   5438 C  CD1   . PHE B 2 198 ? 82.32500  56.10600  35.49400  1.000 357.66000 ? 198 PHE B CD1   1 
ATOM   5439 C  CD2   . PHE B 2 198 ? 84.25800  54.72100  35.65500  1.000 359.07000 ? 198 PHE B CD2   1 
ATOM   5440 C  CE1   . PHE B 2 198 ? 82.57400  56.30900  34.14200  1.000 360.84000 ? 198 PHE B CE1   1 
ATOM   5441 C  CE2   . PHE B 2 198 ? 84.51800  54.93000  34.31300  1.000 360.09000 ? 198 PHE B CE2   1 
ATOM   5442 C  CZ    . PHE B 2 198 ? 83.67400  55.71800  33.55100  1.000 362.55000 ? 198 PHE B CZ    1 
ATOM   5443 N  N     . ASP B 2 199 ? 80.21800  54.15300  36.40600  1.000 355.69000 ? 199 ASP B N     1 
ATOM   5444 C  CA    . ASP B 2 199 ? 79.56800  53.10700  35.63700  1.000 348.55000 ? 199 ASP B CA    1 
ATOM   5445 C  C     . ASP B 2 199 ? 80.59700  52.52600  34.68300  1.000 350.20000 ? 199 ASP B C     1 
ATOM   5446 O  O     . ASP B 2 199 ? 81.29000  53.27600  33.99700  1.000 356.33000 ? 199 ASP B O     1 
ATOM   5447 C  CB    . ASP B 2 199 ? 78.38500  53.68600  34.85800  1.000 351.41000 ? 199 ASP B CB    1 
ATOM   5448 C  CG    . ASP B 2 199 ? 77.45500  52.62000  34.32200  1.000 355.19000 ? 199 ASP B CG    1 
ATOM   5449 O  OD1   . ASP B 2 199 ? 76.25700  52.90100  34.12000  1.000 352.20000 ? 199 ASP B OD1   1 
ATOM   5450 O  OD2   . ASP B 2 199 ? 77.92900  51.47500  34.13900  1.000 360.94000 ? 199 ASP B OD2   1 
ATOM   5451 N  N     . VAL B 2 200 ? 80.71200  51.19800  34.64600  1.000 330.76000 ? 200 VAL B N     1 
ATOM   5452 C  CA    . VAL B 2 200 ? 81.69500  50.55700  33.77500  1.000 337.33000 ? 200 VAL B CA    1 
ATOM   5453 C  C     . VAL B 2 200 ? 81.08900  50.00500  32.50500  1.000 347.20000 ? 200 VAL B C     1 
ATOM   5454 O  O     . VAL B 2 200 ? 81.76700  49.31100  31.75700  1.000 347.92000 ? 200 VAL B O     1 
ATOM   5455 C  CB    . VAL B 2 200 ? 82.36500  49.38500  34.49900  1.000 335.93000 ? 200 VAL B CB    1 
ATOM   5456 C  CG1   . VAL B 2 200 ? 82.75300  49.82000  35.85700  1.000 332.81000 ? 200 VAL B CG1   1 
ATOM   5457 C  CG2   . VAL B 2 200 ? 81.39700  48.27800  34.59200  1.000 335.11000 ? 200 VAL B CG2   1 
ATOM   5458 N  N     . ARG B 2 201 ? 79.84700  50.28000  32.22000  1.000 376.55000 ? 201 ARG B N     1 
ATOM   5459 C  CA    . ARG B 2 201 ? 79.32100  49.70000  30.98800  1.000 375.22000 ? 201 ARG B CA    1 
ATOM   5460 C  C     . ARG B 2 201 ? 79.65200  50.55800  29.76100  1.000 367.12000 ? 201 ARG B C     1 
ATOM   5461 O  O     . ARG B 2 201 ? 79.28000  50.20100  28.63900  1.000 356.38000 ? 201 ARG B O     1 
ATOM   5462 C  CB    . ARG B 2 201 ? 77.80100  49.41600  31.16400  1.000 372.30000 ? 201 ARG B CB    1 
ATOM   5463 C  CG    . ARG B 2 201 ? 77.57000  48.26700  32.20700  1.000 361.54000 ? 201 ARG B CG    1 
ATOM   5464 C  CD    . ARG B 2 201 ? 76.24300  48.30700  32.96800  1.000 350.20000 ? 201 ARG B CD    1 
ATOM   5465 N  NE    . ARG B 2 201 ? 75.92100  49.62500  33.50800  1.000 359.77000 ? 201 ARG B NE    1 
ATOM   5466 C  CZ    . ARG B 2 201 ? 74.81000  50.28500  33.19900  1.000 360.41000 ? 201 ARG B CZ    1 
ATOM   5467 N  NH1   . ARG B 2 201 ? 73.92300  49.73200  32.38300  1.000 359.67000 ? 201 ARG B NH1   1 
ATOM   5468 N  NH2   . ARG B 2 201 ? 74.57200  51.48400  33.70900  1.000 361.77000 ? 201 ARG B NH2   1 
ATOM   5469 N  N     . THR B 2 202 ? 80.35200  51.67200  29.95700  1.000 361.84000 ? 202 THR B N     1 
ATOM   5470 C  CA    . THR B 2 202 ? 81.11000  52.35000  28.91200  1.000 349.08000 ? 202 THR B CA    1 
ATOM   5471 C  C     . THR B 2 202 ? 82.59600  52.02500  29.01300  1.000 354.54000 ? 202 THR B C     1 
ATOM   5472 O  O     . THR B 2 202 ? 83.41800  52.67800  28.36400  1.000 354.71000 ? 202 THR B O     1 
ATOM   5473 C  CB    . THR B 2 202 ? 80.89000  53.87300  28.97100  1.000 350.13000 ? 202 THR B CB    1 
ATOM   5474 O  OG1   . THR B 2 202 ? 79.51700  54.15400  29.26200  1.000 340.52000 ? 202 THR B OG1   1 
ATOM   5475 C  CG2   . THR B 2 202 ? 81.25400  54.54300  27.62700  1.000 343.34000 ? 202 THR B CG2   1 
ATOM   5476 N  N     . LEU B 2 203 ? 82.95100  51.02900  29.82600  1.000 351.45000 ? 203 LEU B N     1 
ATOM   5477 C  CA    . LEU B 2 203 ? 84.31400  50.52700  29.97000  1.000 352.38000 ? 203 LEU B CA    1 
ATOM   5478 C  C     . LEU B 2 203 ? 84.62400  49.46300  28.94900  1.000 347.77000 ? 203 LEU B C     1 
ATOM   5479 O  O     . LEU B 2 203 ? 85.56700  48.69400  29.15400  1.000 346.95000 ? 203 LEU B O     1 
ATOM   5480 C  CB    . LEU B 2 203 ? 84.57100  49.97000  31.38500  1.000 350.65000 ? 203 LEU B CB    1 
ATOM   5481 C  CG    . LEU B 2 203 ? 85.38900  50.85000  32.32100  1.000 355.48000 ? 203 LEU B CG    1 
ATOM   5482 C  CD1   . LEU B 2 203 ? 86.84400  51.13900  31.85300  1.000 357.34000 ? 203 LEU B CD1   1 
ATOM   5483 C  CD2   . LEU B 2 203 ? 84.63900  52.15100  32.56400  1.000 355.97000 ? 203 LEU B CD2   1 
ATOM   5484 N  N     . ALA B 2 204 ? 83.82900  49.37700  27.87700  1.000 353.45000 ? 204 ALA B N     1 
ATOM   5485 C  CA    . ALA B 2 204 ? 84.19500  48.64800  26.66700  1.000 354.98000 ? 204 ALA B CA    1 
ATOM   5486 C  C     . ALA B 2 204 ? 84.68900  47.24300  26.96500  1.000 356.09000 ? 204 ALA B C     1 
ATOM   5487 O  O     . ALA B 2 204 ? 85.22500  46.58400  26.07100  1.000 353.07000 ? 204 ALA B O     1 
ATOM   5488 C  CB    . ALA B 2 204 ? 85.26500  49.41300  25.88600  1.000 360.39000 ? 204 ALA B CB    1 
ATOM   5489 N  N     . PHE B 2 205 ? 84.50000  46.78100  28.20000  1.000 350.18000 ? 205 PHE B N     1 
ATOM   5490 C  CA    . PHE B 2 205 ? 84.79300  45.40800  28.57900  1.000 347.17000 ? 205 PHE B CA    1 
ATOM   5491 C  C     . PHE B 2 205 ? 83.87900  45.02900  29.72500  1.000 346.31000 ? 205 PHE B C     1 
ATOM   5492 O  O     . PHE B 2 205 ? 83.47700  45.88900  30.51600  1.000 345.89000 ? 205 PHE B O     1 
ATOM   5493 C  CB    . PHE B 2 205 ? 86.27400  45.22600  28.95700  1.000 344.52000 ? 205 PHE B CB    1 
ATOM   5494 C  CG    . PHE B 2 205 ? 87.19900  45.24900  27.76300  1.000 351.56000 ? 205 PHE B CG    1 
ATOM   5495 C  CD1   . PHE B 2 205 ? 86.95800  44.45600  26.63700  1.000 345.54000 ? 205 PHE B CD1   1 
ATOM   5496 C  CD2   . PHE B 2 205 ? 88.28100  46.10300  27.73800  1.000 357.29000 ? 205 PHE B CD2   1 
ATOM   5497 C  CE1   . PHE B 2 205 ? 87.80900  44.51100  25.51400  1.000 345.53000 ? 205 PHE B CE1   1 
ATOM   5498 C  CE2   . PHE B 2 205 ? 89.12300  46.15700  26.62900  1.000 355.09000 ? 205 PHE B CE2   1 
ATOM   5499 C  CZ    . PHE B 2 205 ? 88.88200  45.35800  25.52200  1.000 350.84000 ? 205 PHE B CZ    1 
ATOM   5500 N  N     . PRO B 2 206 ? 83.52300  43.77500  29.82900  1.000 347.24000 ? 206 PRO B N     1 
ATOM   5501 C  CA    . PRO B 2 206 ? 82.48800  43.39100  30.78100  1.000 345.26000 ? 206 PRO B CA    1 
ATOM   5502 C  C     . PRO B 2 206 ? 83.03000  43.50700  32.18900  1.000 347.89000 ? 206 PRO B C     1 
ATOM   5503 O  O     . PRO B 2 206 ? 83.95000  42.77500  32.56500  1.000 350.08000 ? 206 PRO B O     1 
ATOM   5504 C  CB    . PRO B 2 206 ? 82.17900  41.94900  30.36900  1.000 336.87000 ? 206 PRO B CB    1 
ATOM   5505 C  CG    . PRO B 2 206 ? 83.52800  41.44100  29.94000  1.000 336.11000 ? 206 PRO B CG    1 
ATOM   5506 C  CD    . PRO B 2 206 ? 84.11200  42.59800  29.16600  1.000 351.95000 ? 206 PRO B CD    1 
ATOM   5507 N  N     . ALA B 2 207 ? 82.52300  44.48400  32.94300  1.000 337.02000 ? 207 ALA B N     1 
ATOM   5508 C  CA    . ALA B 2 207 ? 82.98600  44.74700  34.29900  1.000 334.29000 ? 207 ALA B CA    1 
ATOM   5509 C  C     . ALA B 2 207 ? 81.79700  44.92900  35.22700  1.000 346.30000 ? 207 ALA B C     1 
ATOM   5510 O  O     . ALA B 2 207 ? 80.79500  45.54800  34.85500  1.000 345.81000 ? 207 ALA B O     1 
ATOM   5511 C  CB    . ALA B 2 207 ? 83.88400  45.98500  34.36100  1.000 335.84000 ? 207 ALA B CB    1 
ATOM   5512 N  N     . ILE B 2 208 ? 81.90400  44.37000  36.42900  1.000 347.40000 ? 208 ILE B N     1 
ATOM   5513 C  CA    . ILE B 2 208 ? 80.87300  44.53100  37.44600  1.000 339.79000 ? 208 ILE B CA    1 
ATOM   5514 C  C     . ILE B 2 208 ? 81.48500  44.56700  38.83900  1.000 346.23000 ? 208 ILE B C     1 
ATOM   5515 O  O     . ILE B 2 208 ? 82.54400  43.98200  39.08700  1.000 343.16000 ? 208 ILE B O     1 
ATOM   5516 C  CB    . ILE B 2 208 ? 79.79400  43.41000  37.39500  1.000 338.10000 ? 208 ILE B CB    1 
ATOM   5517 C  CG1   . ILE B 2 208 ? 80.41000  41.96300  37.34000  1.000 339.50000 ? 208 ILE B CG1   1 
ATOM   5518 C  CG2   . ILE B 2 208 ? 78.81000  43.70900  36.33400  1.000 339.16000 ? 208 ILE B CG2   1 
ATOM   5519 C  CD1   . ILE B 2 208 ? 80.27300  41.06200  36.08100  1.000 331.93000 ? 208 ILE B CD1   1 
ATOM   5520 N  N     . ARG B 2 209 ? 80.74900  45.21200  39.76100  1.000 351.19000 ? 209 ARG B N     1 
ATOM   5521 C  CA    . ARG B 2 209 ? 81.14100  45.46800  41.14900  1.000 344.16000 ? 209 ARG B CA    1 
ATOM   5522 C  C     . ARG B 2 209 ? 80.60200  44.37400  42.06100  1.000 342.85000 ? 209 ARG B C     1 
ATOM   5523 O  O     . ARG B 2 209 ? 79.41200  44.36600  42.40700  1.000 342.11000 ? 209 ARG B O     1 
ATOM   5524 C  CB    . ARG B 2 209 ? 80.63200  46.82700  41.63700  1.000 340.36000 ? 209 ARG B CB    1 
ATOM   5525 C  CG    . ARG B 2 209 ? 79.85000  47.62400  40.61200  1.000 336.81000 ? 209 ARG B CG    1 
ATOM   5526 C  CD    . ARG B 2 209 ? 80.75300  48.14800  39.50100  1.000 351.63000 ? 209 ARG B CD    1 
ATOM   5527 N  NE    . ARG B 2 209 ? 81.23200  49.50700  39.68600  1.000 358.07000 ? 209 ARG B NE    1 
ATOM   5528 C  CZ    . ARG B 2 209 ? 82.21600  49.86600  40.50800  1.000 356.33000 ? 209 ARG B CZ    1 
ATOM   5529 N  NH1   . ARG B 2 209 ? 82.59200  51.13500  40.56300  1.000 363.26000 ? 209 ARG B NH1   1 
ATOM   5530 N  NH2   . ARG B 2 209 ? 82.82700  48.98200  41.28200  1.000 355.20000 ? 209 ARG B NH2   1 
ATOM   5531 N  N     . TYR B 2 210 ? 81.49900  43.48600  42.47200  1.000 342.89000 ? 210 TYR B N     1 
ATOM   5532 C  CA    . TYR B 2 210 ? 81.23300  42.38200  43.37600  1.000 342.34000 ? 210 TYR B CA    1 
ATOM   5533 C  C     . TYR B 2 210 ? 82.02700  42.59400  44.65700  1.000 350.79000 ? 210 TYR B C     1 
ATOM   5534 O  O     . TYR B 2 210 ? 83.25900  42.55100  44.61600  1.000 360.52000 ? 210 TYR B O     1 
ATOM   5535 C  CB    . TYR B 2 210 ? 81.67100  41.06800  42.75300  1.000 342.19000 ? 210 TYR B CB    1 
ATOM   5536 C  CG    . TYR B 2 210 ? 81.24700  39.96500  43.66800  1.000 346.69000 ? 210 TYR B CG    1 
ATOM   5537 C  CD1   . TYR B 2 210 ? 79.97200  39.98400  44.18900  1.000 349.59000 ? 210 TYR B CD1   1 
ATOM   5538 C  CD2   . TYR B 2 210 ? 82.11900  38.98100  44.08700  1.000 350.53000 ? 210 TYR B CD2   1 
ATOM   5539 C  CE1   . TYR B 2 210 ? 79.54900  39.04200  45.03800  1.000 346.53000 ? 210 TYR B CE1   1 
ATOM   5540 C  CE2   . TYR B 2 210 ? 81.71200  38.00900  44.95100  1.000 345.73000 ? 210 TYR B CE2   1 
ATOM   5541 C  CZ    . TYR B 2 210 ? 80.41600  38.05800  45.42200  1.000 346.97000 ? 210 TYR B CZ    1 
ATOM   5542 O  OH    . TYR B 2 210 ? 79.89800  37.14700  46.27600  1.000 347.62000 ? 210 TYR B OH    1 
ATOM   5543 N  N     . LYS B 2 211 ? 81.34200  42.83900  45.78500  1.000 368.88000 ? 211 LYS B N     1 
ATOM   5544 C  CA    . LYS B 2 211 ? 82.02800  43.18300  47.04300  1.000 376.46000 ? 211 LYS B CA    1 
ATOM   5545 C  C     . LYS B 2 211 ? 82.96600  44.38600  46.85700  1.000 383.86000 ? 211 LYS B C     1 
ATOM   5546 O  O     . LYS B 2 211 ? 82.56100  45.39900  46.27300  1.000 392.41000 ? 211 LYS B O     1 
ATOM   5547 C  CB    . LYS B 2 211 ? 82.80400  41.97600  47.60100  1.000 370.17000 ? 211 LYS B CB    1 
ATOM   5548 C  CG    . LYS B 2 211 ? 83.06700  41.99400  49.11500  1.000 360.83000 ? 211 LYS B CG    1 
ATOM   5549 C  CD    . LYS B 2 211 ? 83.98200  40.83200  49.44600  1.000 357.95000 ? 211 LYS B CD    1 
ATOM   5550 C  CE    . LYS B 2 211 ? 84.71100  41.01700  50.76100  1.000 345.61000 ? 211 LYS B CE    1 
ATOM   5551 N  NZ    . LYS B 2 211 ? 85.58200  39.83100  51.06300  1.000 348.77000 ? 211 LYS B NZ    1 
ATOM   5552 N  N     . GLU B 2 212 ? 84.21600  44.31100  47.35000  1.000 387.95000 ? 212 GLU B N     1 
ATOM   5553 C  CA    . GLU B 2 212 ? 85.20000  45.36800  47.10400  1.000 382.23000 ? 212 GLU B CA    1 
ATOM   5554 C  C     . GLU B 2 212 ? 86.25900  44.97600  46.07000  1.000 382.96000 ? 212 GLU B C     1 
ATOM   5555 O  O     . GLU B 2 212 ? 87.10000  45.81300  45.71000  1.000 379.29000 ? 212 GLU B O     1 
ATOM   5556 C  CB    . GLU B 2 212 ? 85.89500  45.79500  48.41500  1.000 365.06000 ? 212 GLU B CB    1 
ATOM   5557 C  CG    . GLU B 2 212 ? 84.96100  46.00500  49.59700  1.000 358.66000 ? 212 GLU B CG    1 
ATOM   5558 C  CD    . GLU B 2 212 ? 83.93100  47.09000  49.35900  1.000 359.17000 ? 212 GLU B CD    1 
ATOM   5559 O  OE1   . GLU B 2 212 ? 84.25100  48.28100  49.56300  1.000 351.07000 ? 212 GLU B OE1   1 
ATOM   5560 O  OE2   . GLU B 2 212 ? 82.80000  46.75000  48.95900  1.000 364.05000 ? 212 GLU B OE2   1 
ATOM   5561 N  N     . TYR B 2 213 ? 86.21500  43.73800  45.58100  1.000 389.98000 ? 213 TYR B N     1 
ATOM   5562 C  CA    . TYR B 2 213 ? 87.03600  43.21500  44.50500  1.000 383.98000 ? 213 TYR B CA    1 
ATOM   5563 C  C     . TYR B 2 213 ? 86.35300  43.53200  43.16500  1.000 385.54000 ? 213 TYR B C     1 
ATOM   5564 O  O     . TYR B 2 213 ? 85.18300  43.91800  43.12300  1.000 386.04000 ? 213 TYR B O     1 
ATOM   5565 C  CB    . TYR B 2 213 ? 87.23200  41.69500  44.67900  1.000 381.42000 ? 213 TYR B CB    1 
ATOM   5566 C  CG    . TYR B 2 213 ? 87.67400  41.19800  46.07200  1.000 380.88000 ? 213 TYR B CG    1 
ATOM   5567 C  CD1   . TYR B 2 213 ? 88.66900  40.23500  46.21100  1.000 376.56000 ? 213 TYR B CD1   1 
ATOM   5568 C  CD2   . TYR B 2 213 ? 87.07200  41.66000  47.23900  1.000 381.86000 ? 213 TYR B CD2   1 
ATOM   5569 C  CE1   . TYR B 2 213 ? 89.05400  39.77500  47.46700  1.000 372.87000 ? 213 TYR B CE1   1 
ATOM   5570 C  CE2   . TYR B 2 213 ? 87.46600  41.21900  48.49300  1.000 372.43000 ? 213 TYR B CE2   1 
ATOM   5571 C  CZ    . TYR B 2 213 ? 88.45500  40.27500  48.60600  1.000 369.39000 ? 213 TYR B CZ    1 
ATOM   5572 O  OH    . TYR B 2 213 ? 88.83400  39.82900  49.85900  1.000 364.78000 ? 213 TYR B OH    1 
ATOM   5573 N  N     . LEU B 2 214 ? 87.08100  43.36900  42.05400  1.000 391.36000 ? 214 LEU B N     1 
ATOM   5574 C  CA    . LEU B 2 214 ? 86.54100  43.66000  40.71600  1.000 386.45000 ? 214 LEU B CA    1 
ATOM   5575 C  C     . LEU B 2 214 ? 86.48200  42.40600  39.84200  1.000 381.65000 ? 214 LEU B C     1 
ATOM   5576 O  O     . LEU B 2 214 ? 87.48000  41.69400  39.69300  1.000 389.23000 ? 214 LEU B O     1 
ATOM   5577 C  CB    . LEU B 2 214 ? 87.36600  44.73300  40.00200  1.000 387.92000 ? 214 LEU B CB    1 
ATOM   5578 C  CG    . LEU B 2 214 ? 86.63100  45.81300  39.21500  1.000 384.77000 ? 214 LEU B CG    1 
ATOM   5579 C  CD1   . LEU B 2 214 ? 85.64000  45.19500  38.16800  1.000 372.62000 ? 214 LEU B CD1   1 
ATOM   5580 C  CD2   . LEU B 2 214 ? 85.95100  46.82400  40.18500  1.000 375.26000 ? 214 LEU B CD2   1 
ATOM   5581 N  N     . CYS B 2 215 ? 85.31900  42.14500  39.25400  1.000 356.18000 ? 215 CYS B N     1 
ATOM   5582 C  CA    . CYS B 2 215 ? 85.07400  40.90700  38.52800  1.000 356.10000 ? 215 CYS B CA    1 
ATOM   5583 C  C     . CYS B 2 215 ? 85.10200  41.16700  37.03800  1.000 350.77000 ? 215 CYS B C     1 
ATOM   5584 O  O     . CYS B 2 215 ? 84.44900  42.10500  36.56200  1.000 343.16000 ? 215 CYS B O     1 
ATOM   5585 C  CB    . CYS B 2 215 ? 83.72700  40.29700  38.90700  1.000 352.88000 ? 215 CYS B CB    1 
ATOM   5586 S  SG    . CYS B 2 215 ? 83.06800  39.16900  37.65300  1.000 344.55000 ? 215 CYS B SG    1 
ATOM   5587 N  N     . THR B 2 216 ? 85.86600  40.34100  36.32000  1.000 358.94000 ? 216 THR B N     1 
ATOM   5588 C  CA    . THR B 2 216 ? 85.83800  40.31500  34.86200  1.000 370.72000 ? 216 THR B CA    1 
ATOM   5589 C  C     . THR B 2 216 ? 86.78400  39.20900  34.40100  1.000 369.09000 ? 216 THR B C     1 
ATOM   5590 O  O     . THR B 2 216 ? 87.54700  38.64700  35.19700  1.000 358.83000 ? 216 THR B O     1 
ATOM   5591 C  CB    . THR B 2 216 ? 86.23000  41.66500  34.24100  1.000 373.94000 ? 216 THR B CB    1 
ATOM   5592 O  OG1   . THR B 2 216 ? 86.01900  41.63800  32.81600  1.000 364.54000 ? 216 THR B OG1   1 
ATOM   5593 C  CG2   . THR B 2 216 ? 87.66500  41.96200  34.52200  1.000 376.88000 ? 216 THR B CG2   1 
ATOM   5594 N  N     . PHE B 2 217 ? 86.69800  38.89100  33.09600  1.000 375.96000 ? 217 PHE B N     1 
ATOM   5595 C  CA    . PHE B 2 217 ? 87.67300  38.08900  32.35800  1.000 369.30000 ? 217 PHE B CA    1 
ATOM   5596 C  C     . PHE B 2 217 ? 88.76200  38.93000  31.73300  1.000 369.99000 ? 217 PHE B C     1 
ATOM   5597 O  O     . PHE B 2 217 ? 89.72400  38.36800  31.20000  1.000 364.74000 ? 217 PHE B O     1 
ATOM   5598 C  CB    . PHE B 2 217 ? 87.01900  37.29400  31.24100  1.000 361.09000 ? 217 PHE B CB    1 
ATOM   5599 C  CG    . PHE B 2 217 ? 86.05300  36.31200  31.72700  1.000 362.25000 ? 217 PHE B CG    1 
ATOM   5600 C  CD1   . PHE B 2 217 ? 86.48100  35.09600  32.23500  1.000 364.52000 ? 217 PHE B CD1   1 
ATOM   5601 C  CD2   . PHE B 2 217 ? 84.70600  36.61100  31.72600  1.000 371.80000 ? 217 PHE B CD2   1 
ATOM   5602 C  CE1   . PHE B 2 217 ? 85.57300  34.18700  32.71300  1.000 369.56000 ? 217 PHE B CE1   1 
ATOM   5603 C  CE2   . PHE B 2 217 ? 83.79100  35.70800  32.20100  1.000 369.21000 ? 217 PHE B CE2   1 
ATOM   5604 C  CZ    . PHE B 2 217 ? 84.22500  34.49100  32.70200  1.000 365.70000 ? 217 PHE B CZ    1 
ATOM   5605 N  N     . ALA B 2 218 ? 88.59800  40.25300  31.73100  1.000 367.18000 ? 218 ALA B N     1 
ATOM   5606 C  CA    . ALA B 2 218 ? 89.67400  41.16500  31.37900  1.000 376.51000 ? 218 ALA B CA    1 
ATOM   5607 C  C     . ALA B 2 218 ? 90.73800  41.16600  32.47500  1.000 394.57000 ? 218 ALA B C     1 
ATOM   5608 O  O     . ALA B 2 218 ? 90.41700  41.29200  33.66800  1.000 404.13000 ? 218 ALA B O     1 
ATOM   5609 C  CB    . ALA B 2 218 ? 89.12100  42.58000  31.14700  1.000 373.60000 ? 218 ALA B CB    1 
ATOM   5610 N  N     . TRP B 2 219 ? 91.99800  40.96600  32.06100  1.000 391.40000 ? 219 TRP B N     1 
ATOM   5611 C  CA    . TRP B 2 219 ? 93.13600  41.08800  32.95800  1.000 392.23000 ? 219 TRP B CA    1 
ATOM   5612 C  C     . TRP B 2 219 ? 93.33600  42.55800  33.37800  1.000 394.84000 ? 219 TRP B C     1 
ATOM   5613 O  O     . TRP B 2 219 ? 93.23100  43.49200  32.57000  1.000 390.75000 ? 219 TRP B O     1 
ATOM   5614 C  CB    . TRP B 2 219 ? 94.38500  40.52200  32.27700  1.000 379.39000 ? 219 TRP B CB    1 
ATOM   5615 C  CG    . TRP B 2 219 ? 94.57900  39.01700  32.39400  1.000 379.92000 ? 219 TRP B CG    1 
ATOM   5616 C  CD1   . TRP B 2 219 ? 94.04300  38.05200  31.60200  1.000 371.16000 ? 219 TRP B CD1   1 
ATOM   5617 C  CD2   . TRP B 2 219 ? 95.41400  38.33800  33.32800  1.000 381.79000 ? 219 TRP B CD2   1 
ATOM   5618 N  NE1   . TRP B 2 219 ? 94.46800  36.80900  32.00100  1.000 371.21000 ? 219 TRP B NE1   1 
ATOM   5619 C  CE2   . TRP B 2 219 ? 95.31700  36.96100  33.06400  1.000 376.61000 ? 219 TRP B CE2   1 
ATOM   5620 C  CE3   . TRP B 2 219 ? 96.22100  38.76300  34.38000  1.000 382.96000 ? 219 TRP B CE3   1 
ATOM   5621 C  CZ2   . TRP B 2 219 ? 96.00900  36.00700  33.82000  1.000 380.91000 ? 219 TRP B CZ2   1 
ATOM   5622 C  CZ3   . TRP B 2 219 ? 96.90500  37.82800  35.12200  1.000 385.70000 ? 219 TRP B CZ3   1 
ATOM   5623 C  CH2   . TRP B 2 219 ? 96.79900  36.46800  34.84400  1.000 384.17000 ? 219 TRP B CH2   1 
ATOM   5624 N  N     . GLU B 2 220 ? 93.64300  42.74600  34.67100  1.000 400.12000 ? 220 GLU B N     1 
ATOM   5625 C  CA    . GLU B 2 220 ? 93.73000  44.07500  35.29000  1.000 395.58000 ? 220 GLU B CA    1 
ATOM   5626 C  C     . GLU B 2 220 ? 94.30800  45.14700  34.35600  1.000 384.10000 ? 220 GLU B C     1 
ATOM   5627 O  O     . GLU B 2 220 ? 93.84100  46.30200  34.35700  1.000 374.78000 ? 220 GLU B O     1 
ATOM   5628 C  CB    . GLU B 2 220 ? 94.54000  43.95600  36.59500  1.000 396.81000 ? 220 GLU B CB    1 
ATOM   5629 C  CG    . GLU B 2 220 ? 95.98600  43.37300  36.52000  1.000 398.10000 ? 220 GLU B CG    1 
ATOM   5630 C  CD    . GLU B 2 220 ? 96.06700  41.85500  36.33600  1.000 395.87000 ? 220 GLU B CD    1 
ATOM   5631 O  OE1   . GLU B 2 220 ? 96.91000  41.19100  36.99100  1.000 393.62000 ? 220 GLU B OE1   1 
ATOM   5632 O  OE2   . GLU B 2 220 ? 95.29200  41.32100  35.51600  1.000 402.19000 ? 220 GLU B OE2   1 
ATOM   5633 N  N     . TYR B 2 221 ? 95.28400  44.78100  33.52200  1.000 370.06000 ? 221 TYR B N     1 
ATOM   5634 C  CA    . TYR B 2 221 ? 95.94800  45.78800  32.70200  1.000 370.06000 ? 221 TYR B CA    1 
ATOM   5635 C  C     . TYR B 2 221 ? 95.04200  46.39200  31.64000  1.000 369.82000 ? 221 TYR B C     1 
ATOM   5636 O  O     . TYR B 2 221 ? 95.47700  47.27500  30.90100  1.000 363.50000 ? 221 TYR B O     1 
ATOM   5637 C  CB    . TYR B 2 221 ? 97.14100  45.19100  31.98100  1.000 366.03000 ? 221 TYR B CB    1 
ATOM   5638 C  CG    . TYR B 2 221 ? 97.62200  43.92500  32.60400  1.000 365.95000 ? 221 TYR B CG    1 
ATOM   5639 C  CD1   . TYR B 2 221 ? 98.52000  43.95700  33.65800  1.000 371.20000 ? 221 TYR B CD1   1 
ATOM   5640 C  CD2   . TYR B 2 221 ? 97.17400  42.68500  32.16600  1.000 367.95000 ? 221 TYR B CD2   1 
ATOM   5641 C  CE1   . TYR B 2 221 ? 98.95800  42.78900  34.26600  1.000 382.61000 ? 221 TYR B CE1   1 
ATOM   5642 C  CE2   . TYR B 2 221 ? 97.62200  41.50700  32.76700  1.000 372.75000 ? 221 TYR B CE2   1 
ATOM   5643 C  CZ    . TYR B 2 221 ? 98.49900  41.56000  33.81000  1.000 381.28000 ? 221 TYR B CZ    1 
ATOM   5644 O  OH    . TYR B 2 221 ? 98.93000  40.39200  34.40600  1.000 389.42000 ? 221 TYR B OH    1 
ATOM   5645 N  N     . ASP B 2 222 ? 93.80100  45.93400  31.51700  1.000 366.79000 ? 222 ASP B N     1 
ATOM   5646 C  CA    . ASP B 2 222 ? 93.07300  46.16900  30.27300  1.000 358.96000 ? 222 ASP B CA    1 
ATOM   5647 C  C     . ASP B 2 222 ? 92.34800  47.50100  30.28700  1.000 355.12000 ? 222 ASP B C     1 
ATOM   5648 O  O     . ASP B 2 222 ? 92.20700  48.13300  29.24800  1.000 354.75000 ? 222 ASP B O     1 
ATOM   5649 C  CB    . ASP B 2 222 ? 92.10400  45.02000  29.99400  1.000 369.21000 ? 222 ASP B CB    1 
ATOM   5650 C  CG    . ASP B 2 222 ? 92.84800  43.72800  29.58900  1.000 368.36000 ? 222 ASP B CG    1 
ATOM   5651 O  OD1   . ASP B 2 222 ? 93.90900  43.78900  28.93800  1.000 367.90000 ? 222 ASP B OD1   1 
ATOM   5652 O  OD2   . ASP B 2 222 ? 92.39400  42.63100  29.91300  1.000 370.66000 ? 222 ASP B OD2   1 
ATOM   5653 N  N     . PHE B 2 223 ? 91.92800  47.97200  31.44500  1.000 352.94000 ? 223 PHE B N     1 
ATOM   5654 C  CA    . PHE B 2 223 ? 91.20000  49.23000  31.54500  1.000 356.01000 ? 223 PHE B CA    1 
ATOM   5655 C  C     . PHE B 2 223 ? 92.19800  50.34000  31.83200  1.000 348.83000 ? 223 PHE B C     1 
ATOM   5656 O  O     . PHE B 2 223 ? 92.64800  50.49900  32.96800  1.000 350.07000 ? 223 PHE B O     1 
ATOM   5657 C  CB    . PHE B 2 223 ? 90.12300  49.16000  32.62500  1.000 360.10000 ? 223 PHE B CB    1 
ATOM   5658 C  CG    . PHE B 2 223 ? 89.26100  47.90000  32.58000  1.000 355.41000 ? 223 PHE B CG    1 
ATOM   5659 C  CD1   . PHE B 2 223 ? 87.95700  47.94000  32.09200  1.000 349.00000 ? 223 PHE B CD1   1 
ATOM   5660 C  CD2   . PHE B 2 223 ? 89.74200  46.69200  33.06700  1.000 363.08000 ? 223 PHE B CD2   1 
ATOM   5661 C  CE1   . PHE B 2 223 ? 87.15500  46.80400  32.06800  1.000 341.28000 ? 223 PHE B CE1   1 
ATOM   5662 C  CE2   . PHE B 2 223 ? 88.94300  45.54500  33.03800  1.000 366.71000 ? 223 PHE B CE2   1 
ATOM   5663 C  CZ    . PHE B 2 223 ? 87.64800  45.60400  32.53900  1.000 349.41000 ? 223 PHE B CZ    1 
ATOM   5664 N  N     . ILE B 2 224 ? 92.53500  51.11900  30.80700  1.000 341.00000 ? 224 ILE B N     1 
ATOM   5665 C  CA    . ILE B 2 224 ? 93.55200  52.14700  30.96400  1.000 351.20000 ? 224 ILE B CA    1 
ATOM   5666 C  C     . ILE B 2 224 ? 92.95300  53.52500  30.71400  1.000 358.50000 ? 224 ILE B C     1 
ATOM   5667 O  O     . ILE B 2 224 ? 92.99600  54.39500  31.59500  1.000 360.71000 ? 224 ILE B O     1 
ATOM   5668 C  CB    . ILE B 2 224 ? 94.72800  51.85900  30.02500  1.000 347.06000 ? 224 ILE B CB    1 
ATOM   5669 C  CG1   . ILE B 2 224 ? 95.81300  51.03900  30.70600  1.000 340.98000 ? 224 ILE B CG1   1 
ATOM   5670 C  CG2   . ILE B 2 224 ? 95.38600  53.15000  29.59800  1.000 348.95000 ? 224 ILE B CG2   1 
ATOM   5671 C  CD1   . ILE B 2 224 ? 95.41000  50.16000  31.88600  1.000 335.23000 ? 224 ILE B CD1   1 
ATOM   5672 N  N     . HIS B 2 225 ? 92.35500  53.71900  29.53200  1.000 378.92000 ? 225 HIS B N     1 
ATOM   5673 C  CA    . HIS B 2 225 ? 91.88100  55.04700  29.14800  1.000 383.64000 ? 225 HIS B CA    1 
ATOM   5674 C  C     . HIS B 2 225 ? 90.83500  55.55900  30.11500  1.000 377.32000 ? 225 HIS B C     1 
ATOM   5675 O  O     . HIS B 2 225 ? 90.79600  56.77200  30.42000  1.000 381.67000 ? 225 HIS B O     1 
ATOM   5676 C  CB    . HIS B 2 225 ? 91.37900  54.97800  27.68100  1.000 400.88000 ? 225 HIS B CB    1 
ATOM   5677 C  CG    . HIS B 2 225 ? 90.36700  56.01700  27.25000  1.000 399.03000 ? 225 HIS B CG    1 
ATOM   5678 N  ND1   . HIS B 2 225 ? 90.35000  56.53100  25.97300  1.000 392.24000 ? 225 HIS B ND1   1 
ATOM   5679 C  CD2   . HIS B 2 225 ? 89.28400  56.54700  27.86500  1.000 390.69000 ? 225 HIS B CD2   1 
ATOM   5680 C  CE1   . HIS B 2 225 ? 89.33400  57.36400  25.84000  1.000 380.42000 ? 225 HIS B CE1   1 
ATOM   5681 N  NE2   . HIS B 2 225 ? 88.66900  57.39300  26.97700  1.000 386.24000 ? 225 HIS B NE2   1 
ATOM   5682 N  N     . GLN B 2 226 ? 89.98700  54.67000  30.61100  1.000 364.31000 ? 226 GLN B N     1 
ATOM   5683 C  CA    . GLN B 2 226 ? 88.91900  55.15300  31.44900  1.000 362.90000 ? 226 GLN B CA    1 
ATOM   5684 C  C     . GLN B 2 226 ? 89.15600  54.85700  32.91600  1.000 368.72000 ? 226 GLN B C     1 
ATOM   5685 O  O     . GLN B 2 226 ? 88.21500  54.97500  33.70000  1.000 371.43000 ? 226 GLN B O     1 
ATOM   5686 C  CB    . GLN B 2 226 ? 87.55300  54.52800  31.01800  1.000 363.39000 ? 226 GLN B CB    1 
ATOM   5687 C  CG    . GLN B 2 226 ? 86.61700  55.46100  30.15200  1.000 367.58000 ? 226 GLN B CG    1 
ATOM   5688 C  CD    . GLN B 2 226 ? 86.27400  54.65000  28.92000  1.000 369.22000 ? 226 GLN B CD    1 
ATOM   5689 O  OE1   . GLN B 2 226 ? 86.09600  53.43400  29.01500  1.000 374.45000 ? 226 GLN B OE1   1 
ATOM   5690 N  NE2   . GLN B 2 226 ? 86.27900  55.28600  27.73700  1.000 374.95000 ? 226 GLN B NE2   1 
ATOM   5691 N  N     . LEU B 2 227 ? 90.36400  54.47400  33.32000  1.000 367.66000 ? 227 LEU B N     1 
ATOM   5692 C  CA    . LEU B 2 227 ? 90.61200  54.00300  34.68600  1.000 377.29000 ? 227 LEU B CA    1 
ATOM   5693 C  C     . LEU B 2 227 ? 92.06300  54.28500  35.06800  1.000 383.25000 ? 227 LEU B C     1 
ATOM   5694 O  O     . LEU B 2 227 ? 92.92900  53.40300  35.01700  1.000 386.44000 ? 227 LEU B O     1 
ATOM   5695 C  CB    . LEU B 2 227 ? 90.28300  52.52500  34.84900  1.000 377.10000 ? 227 LEU B CB    1 
ATOM   5696 C  CG    . LEU B 2 227 ? 89.67900  52.00200  36.12200  1.000 381.51000 ? 227 LEU B CG    1 
ATOM   5697 C  CD1   . LEU B 2 227 ? 89.38600  50.57600  35.80300  1.000 382.43000 ? 227 LEU B CD1   1 
ATOM   5698 C  CD2   . LEU B 2 227 ? 90.63300  52.09000  37.32400  1.000 382.78000 ? 227 LEU B CD2   1 
ATOM   5699 N  N     . PRO B 2 228 ? 92.36400  55.51400  35.46500  1.000 383.71000 ? 228 PRO B N     1 
ATOM   5700 C  CA    . PRO B 2 228 ? 93.75200  55.92900  35.69300  1.000 380.66000 ? 228 PRO B CA    1 
ATOM   5701 C  C     . PRO B 2 228 ? 94.28600  55.42500  37.02900  1.000 379.06000 ? 228 PRO B C     1 
ATOM   5702 O  O     . PRO B 2 228 ? 93.58200  54.80700  37.82400  1.000 375.07000 ? 228 PRO B O     1 
ATOM   5703 C  CB    . PRO B 2 228 ? 93.65500  57.45300  35.67800  1.000 378.97000 ? 228 PRO B CB    1 
ATOM   5704 C  CG    . PRO B 2 228 ? 92.24500  57.74100  36.12600  1.000 375.75000 ? 228 PRO B CG    1 
ATOM   5705 C  CD    . PRO B 2 228 ? 91.41800  56.63500  35.56400  1.000 381.67000 ? 228 PRO B CD    1 
ATOM   5706 N  N     . LYS B 2 229 ? 95.56900  55.70100  37.24300  1.000 373.19000 ? 229 LYS B N     1 
ATOM   5707 C  CA    . LYS B 2 229 ? 96.26700  55.48300  38.51100  1.000 372.08000 ? 229 LYS B CA    1 
ATOM   5708 C  C     . LYS B 2 229 ? 95.99800  54.08800  39.07300  1.000 368.48000 ? 229 LYS B C     1 
ATOM   5709 O  O     . LYS B 2 229 ? 95.74500  53.89700  40.26400  1.000 365.52000 ? 229 LYS B O     1 
ATOM   5710 C  CB    . LYS B 2 229 ? 95.91400  56.58600  39.51800  1.000 363.35000 ? 229 LYS B CB    1 
ATOM   5711 C  CG    . LYS B 2 229 ? 96.88500  57.78500  39.48900  1.000 344.27000 ? 229 LYS B CG    1 
ATOM   5712 C  CD    . LYS B 2 229 ? 96.43200  58.96900  40.35400  1.000 328.32000 ? 229 LYS B CD    1 
ATOM   5713 C  CE    . LYS B 2 229 ? 97.46600  60.10900  40.33200  1.000 305.99000 ? 229 LYS B CE    1 
ATOM   5714 N  NZ    . LYS B 2 229 ? 97.00400  61.36900  40.99000  1.000 295.62000 ? 229 LYS B NZ    1 
ATOM   5715 N  N     . THR B 2 230 ? 96.06900  53.09300  38.19100  1.000 370.51000 ? 230 THR B N     1 
ATOM   5716 C  CA    . THR B 2 230 ? 95.92900  51.69800  38.58800  1.000 374.40000 ? 230 THR B CA    1 
ATOM   5717 C  C     . THR B 2 230 ? 97.16600  50.87900  38.23900  1.000 373.44000 ? 230 THR B C     1 
ATOM   5718 O  O     . THR B 2 230 ? 97.17500  49.66000  38.44300  1.000 381.71000 ? 230 THR B O     1 
ATOM   5719 C  CB    . THR B 2 230 ? 94.67700  51.08800  37.95600  1.000 372.25000 ? 230 THR B CB    1 
ATOM   5720 O  OG1   . THR B 2 230 ? 93.61900  52.04200  38.03300  1.000 371.09000 ? 230 THR B OG1   1 
ATOM   5721 C  CG2   . THR B 2 230 ? 94.23600  49.84900  38.71800  1.000 371.21000 ? 230 THR B CG2   1 
ATOM   5722 N  N     . GLU B 2 231 ? 98.23400  51.51300  37.77700  1.000 367.13000 ? 231 GLU B N     1 
ATOM   5723 C  CA    . GLU B 2 231 ? 99.47900  50.75600  37.65300  1.000 369.99000 ? 231 GLU B CA    1 
ATOM   5724 C  C     . GLU B 2 231 ? 100.06000 50.37600  39.02400  1.000 377.77000 ? 231 GLU B C     1 
ATOM   5725 O  O     . GLU B 2 231 ? 101.18500 49.86600  39.15000  1.000 382.27000 ? 231 GLU B O     1 
ATOM   5726 C  CB    . GLU B 2 231 ? 100.47400 51.58100  36.83700  1.000 366.35000 ? 231 GLU B CB    1 
ATOM   5727 C  CG    . GLU B 2 231 ? 99.77500  52.50300  35.83700  1.000 359.39000 ? 231 GLU B CG    1 
ATOM   5728 C  CD    . GLU B 2 231 ? 100.67300 53.58000  35.25700  1.000 353.45000 ? 231 GLU B CD    1 
ATOM   5729 O  OE1   . GLU B 2 231 ? 101.81300 53.27000  34.85400  1.000 351.98000 ? 231 GLU B OE1   1 
ATOM   5730 O  OE2   . GLU B 2 231 ? 100.22900 54.74500  35.20000  1.000 350.95000 ? 231 GLU B OE2   1 
ATOM   5731 N  N     . THR B 2 232 ? 99.21300  50.64300  40.02000  1.000 390.87000 ? 232 THR B N     1 
ATOM   5732 C  CA    . THR B 2 232 ? 99.52400  50.58000  41.43700  1.000 395.24000 ? 232 THR B CA    1 
ATOM   5733 C  C     . THR B 2 232 ? 99.04800  49.29300  42.06400  1.000 391.52000 ? 232 THR B C     1 
ATOM   5734 O  O     . THR B 2 232 ? 99.10900  49.14300  43.28600  1.000 396.64000 ? 232 THR B O     1 
ATOM   5735 C  CB    . THR B 2 232 ? 98.87600  51.75400  42.15500  1.000 396.20000 ? 232 THR B CB    1 
ATOM   5736 O  OG1   . THR B 2 232 ? 97.46700  51.49300  42.29400  1.000 398.01000 ? 232 THR B OG1   1 
ATOM   5737 C  CG2   . THR B 2 232 ? 99.06300  53.02800  41.35000  1.000 391.22000 ? 232 THR B CG2   1 
ATOM   5738 N  N     . TYR B 2 233 ? 98.55100  48.37400  41.25900  1.000 381.54000 ? 233 TYR B N     1 
ATOM   5739 C  CA    . TYR B 2 233 ? 97.94100  47.16100  41.75400  1.000 380.43000 ? 233 TYR B CA    1 
ATOM   5740 C  C     . TYR B 2 233 ? 98.88000  45.99500  41.49300  1.000 376.47000 ? 233 TYR B C     1 
ATOM   5741 O  O     . TYR B 2 233 ? 99.31400  45.77500  40.35300  1.000 369.80000 ? 233 TYR B O     1 
ATOM   5742 C  CB    . TYR B 2 233 ? 96.58200  46.94200  41.10500  1.000 381.46000 ? 233 TYR B CB    1 
ATOM   5743 C  CG    . TYR B 2 233 ? 95.90800  45.77400  41.70500  1.000 379.11000 ? 233 TYR B CG    1 
ATOM   5744 C  CD1   . TYR B 2 233 ? 95.68400  44.62200  40.96900  1.000 376.87000 ? 233 TYR B CD1   1 
ATOM   5745 C  CD2   . TYR B 2 233 ? 95.56800  45.78600  43.03200  1.000 381.42000 ? 233 TYR B CD2   1 
ATOM   5746 C  CE1   . TYR B 2 233 ? 95.09000  43.52100  41.53300  1.000 378.54000 ? 233 TYR B CE1   1 
ATOM   5747 C  CE2   . TYR B 2 233 ? 94.97400  44.70000  43.60700  1.000 391.54000 ? 233 TYR B CE2   1 
ATOM   5748 C  CZ    . TYR B 2 233 ? 94.73200  43.56200  42.85500  1.000 387.72000 ? 233 TYR B CZ    1 
ATOM   5749 O  OH    . TYR B 2 233 ? 94.13500  42.47800  43.46400  1.000 395.45000 ? 233 TYR B OH    1 
ATOM   5750 N  N     . ASN B 2 234 ? 99.26000  45.31100  42.56700  1.000 384.63000 ? 234 ASN B N     1 
ATOM   5751 C  CA    . ASN B 2 234 ? 100.08700 44.12700  42.42200  1.000 393.17000 ? 234 ASN B CA    1 
ATOM   5752 C  C     . ASN B 2 234 ? 99.37400  43.13900  41.49600  1.000 382.42000 ? 234 ASN B C     1 
ATOM   5753 O  O     . ASN B 2 234 ? 98.15000  42.96200  41.56600  1.000 376.93000 ? 234 ASN B O     1 
ATOM   5754 C  CB    . ASN B 2 234 ? 100.39800 43.50000  43.80200  1.000 401.14000 ? 234 ASN B CB    1 
ATOM   5755 C  CG    . ASN B 2 234 ? 100.92600 44.52000  44.84100  1.000 387.68000 ? 234 ASN B CG    1 
ATOM   5756 O  OD1   . ASN B 2 234 ? 100.51400 44.50500  46.00400  1.000 379.75000 ? 234 ASN B OD1   1 
ATOM   5757 N  ND2   . ASN B 2 234 ? 101.83900 45.39000  44.42100  1.000 380.85000 ? 234 ASN B ND2   1 
ATOM   5758 N  N     . GLY B 2 235 ? 100.13800 42.54100  40.57500  1.000 371.84000 ? 235 GLY B N     1 
ATOM   5759 C  CA    . GLY B 2 235 ? 99.56300  41.51100  39.73100  1.000 374.49000 ? 235 GLY B CA    1 
ATOM   5760 C  C     . GLY B 2 235 ? 99.16600  40.29400  40.54100  1.000 378.44000 ? 235 GLY B C     1 
ATOM   5761 O  O     . GLY B 2 235 ? 98.22800  39.58300  40.18900  1.000 380.56000 ? 235 GLY B O     1 
ATOM   5762 N  N     . GLN B 2 236 ? 99.88900  40.04100  41.64100  1.000 386.07000 ? 236 GLN B N     1 
ATOM   5763 C  CA    . GLN B 2 236 ? 99.65500  38.87200  42.48400  1.000 379.85000 ? 236 GLN B CA    1 
ATOM   5764 C  C     . GLN B 2 236 ? 98.38400  39.01100  43.28500  1.000 386.01000 ? 236 GLN B C     1 
ATOM   5765 O  O     . GLN B 2 236 ? 97.65800  38.03700  43.45400  1.000 388.88000 ? 236 GLN B O     1 
ATOM   5766 C  CB    . GLN B 2 236 ? 100.81700 38.66600  43.46100  1.000 378.62000 ? 236 GLN B CB    1 
ATOM   5767 C  CG    . GLN B 2 236 ? 102.18100 38.44600  42.90700  1.000 375.04000 ? 236 GLN B CG    1 
ATOM   5768 C  CD    . GLN B 2 236 ? 102.76300 39.65900  42.21000  1.000 378.44000 ? 236 GLN B CD    1 
ATOM   5769 O  OE1   . GLN B 2 236 ? 102.13700 40.25400  41.32400  1.000 382.13000 ? 236 GLN B OE1   1 
ATOM   5770 N  NE2   . GLN B 2 236 ? 103.98800 40.01400  42.58200  1.000 378.76000 ? 236 GLN B NE2   1 
ATOM   5771 N  N     . GLU B 2 237 ? 98.12800  40.20100  43.82800  1.000 390.98000 ? 237 GLU B N     1 
ATOM   5772 C  CA    . GLU B 2 237 ? 97.15900  40.34700  44.91000  1.000 388.55000 ? 237 GLU B CA    1 
ATOM   5773 C  C     . GLU B 2 237 ? 95.79400  39.74100  44.56400  1.000 390.31000 ? 237 GLU B C     1 
ATOM   5774 O  O     . GLU B 2 237 ? 94.96600  39.54800  45.46300  1.000 393.82000 ? 237 GLU B O     1 
ATOM   5775 C  CB    . GLU B 2 237 ? 97.03400  41.83000  45.27600  1.000 389.17000 ? 237 GLU B CB    1 
ATOM   5776 C  CG    . GLU B 2 237 ? 96.09500  42.20100  46.50600  1.000 375.55000 ? 237 GLU B CG    1 
ATOM   5777 C  CD    . GLU B 2 237 ? 96.38400  43.55600  47.19800  1.000 378.57000 ? 237 GLU B CD    1 
ATOM   5778 O  OE1   . GLU B 2 237 ? 97.56200  43.96300  47.30300  1.000 385.99000 ? 237 GLU B OE1   1 
ATOM   5779 O  OE2   . GLU B 2 237 ? 95.41600  44.20100  47.66900  1.000 375.82000 ? 237 GLU B OE2   1 
ATOM   5780 N  N     . SER B 2 238 ? 95.51800  39.45000  43.28700  1.000 396.51000 ? 238 SER B N     1 
ATOM   5781 C  CA    . SER B 2 238 ? 94.13000  39.19500  42.92200  1.000 392.96000 ? 238 SER B CA    1 
ATOM   5782 C  C     . SER B 2 238 ? 93.86600  37.70300  42.83200  1.000 386.71000 ? 238 SER B C     1 
ATOM   5783 O  O     . SER B 2 238 ? 94.66300  36.93000  42.28200  1.000 385.87000 ? 238 SER B O     1 
ATOM   5784 C  CB    . SER B 2 238 ? 93.75800  39.85300  41.56100  1.000 387.98000 ? 238 SER B CB    1 
ATOM   5785 O  OG    . SER B 2 238 ? 93.16700  41.15700  41.52700  1.000 388.56000 ? 238 SER B OG    1 
ATOM   5786 N  N     . ILE B 2 239 ? 92.72800  37.31200  43.40200  1.000 387.70000 ? 239 ILE B N     1 
ATOM   5787 C  CA    . ILE B 2 239 ? 92.30100  35.93700  43.30400  1.000 385.27000 ? 239 ILE B CA    1 
ATOM   5788 C  C     . ILE B 2 239 ? 92.21200  35.57000  41.83600  1.000 387.76000 ? 239 ILE B C     1 
ATOM   5789 O  O     . ILE B 2 239 ? 91.83200  36.39100  40.98900  1.000 391.81000 ? 239 ILE B O     1 
ATOM   5790 C  CB    . ILE B 2 239 ? 90.96800  35.71100  44.02800  1.000 382.13000 ? 239 ILE B CB    1 
ATOM   5791 C  CG1   . ILE B 2 239 ? 90.62900  36.78900  45.07000  1.000 382.65000 ? 239 ILE B CG1   1 
ATOM   5792 C  CG2   . ILE B 2 239 ? 91.08400  34.42100  44.69000  1.000 379.44000 ? 239 ILE B CG2   1 
ATOM   5793 C  CD1   . ILE B 2 239 ? 89.40800  36.35500  45.98300  1.000 377.61000 ? 239 ILE B CD1   1 
ATOM   5794 N  N     . ARG B 2 240 ? 92.70000  34.38100  41.52400  1.000 386.41000 ? 240 ARG B N     1 
ATOM   5795 C  CA    . ARG B 2 240 ? 92.79100  33.86900  40.17200  1.000 384.67000 ? 240 ARG B CA    1 
ATOM   5796 C  C     . ARG B 2 240 ? 92.15900  32.49000  40.24300  1.000 389.89000 ? 240 ARG B C     1 
ATOM   5797 O  O     . ARG B 2 240 ? 92.86700  31.48300  40.33800  1.000 391.79000 ? 240 ARG B O     1 
ATOM   5798 C  CB    . ARG B 2 240 ? 94.21300  33.81300  39.73700  1.000 392.24000 ? 240 ARG B CB    1 
ATOM   5799 C  CG    . ARG B 2 240 ? 94.82000  35.16700  39.58000  1.000 393.73000 ? 240 ARG B CG    1 
ATOM   5800 C  CD    . ARG B 2 240 ? 96.09400  35.01600  38.83100  1.000 390.36000 ? 240 ARG B CD    1 
ATOM   5801 N  NE    . ARG B 2 240 ? 96.81700  36.27000  38.75500  1.000 397.77000 ? 240 ARG B NE    1 
ATOM   5802 C  CZ    . ARG B 2 240 ? 97.95800  36.40600  38.09800  1.000 401.08000 ? 240 ARG B CZ    1 
ATOM   5803 N  NH1   . ARG B 2 240 ? 98.47500  35.35500  37.47700  1.000 401.57000 ? 240 ARG B NH1   1 
ATOM   5804 N  NH2   . ARG B 2 240 ? 98.58200  37.57600  38.06200  1.000 404.14000 ? 240 ARG B NH2   1 
ATOM   5805 N  N     . ILE B 2 241 ? 90.83200  32.46300  40.16600  1.000 399.46000 ? 241 ILE B N     1 
ATOM   5806 C  CA    . ILE B 2 241 ? 90.03000  31.25600  40.35100  1.000 390.57000 ? 241 ILE B CA    1 
ATOM   5807 C  C     . ILE B 2 241 ? 89.89600  30.51000  39.01600  1.000 385.56000 ? 241 ILE B C     1 
ATOM   5808 O  O     . ILE B 2 241 ? 89.54400  31.10700  37.98600  1.000 386.04000 ? 241 ILE B O     1 
ATOM   5809 C  CB    . ILE B 2 241 ? 88.64800  31.61800  40.93500  1.000 389.56000 ? 241 ILE B CB    1 
ATOM   5810 C  CG1   . ILE B 2 241 ? 88.75400  32.40400  42.26100  1.000 386.01000 ? 241 ILE B CG1   1 
ATOM   5811 C  CG2   . ILE B 2 241 ? 87.86400  30.38300  41.18400  1.000 381.19000 ? 241 ILE B CG2   1 
ATOM   5812 C  CD1   . ILE B 2 241 ? 87.38800  32.96700  42.78800  1.000 383.58000 ? 241 ILE B CD1   1 
ATOM   5813 N  N     . SER B 2 242 ? 90.14800  29.19200  39.04700  1.000 388.85000 ? 242 SER B N     1 
ATOM   5814 C  CA    . SER B 2 242 ? 90.21200  28.36200  37.83900  1.000 385.17000 ? 242 SER B CA    1 
ATOM   5815 C  C     . SER B 2 242 ? 88.81600  28.13800  37.25100  1.000 381.00000 ? 242 SER B C     1 
ATOM   5816 O  O     . SER B 2 242 ? 87.97100  27.49000  37.86800  1.000 388.05000 ? 242 SER B O     1 
ATOM   5817 C  CB    . SER B 2 242 ? 90.88300  27.01700  38.17400  1.000 382.56000 ? 242 SER B CB    1 
ATOM   5818 O  OG    . SER B 2 242 ? 91.03000  26.15600  37.04600  1.000 379.40000 ? 242 SER B OG    1 
ATOM   5819 N  N     . THR B 2 243 ? 88.58700  28.66500  36.04600  1.000 373.29000 ? 243 THR B N     1 
ATOM   5820 C  CA    . THR B 2 243 ? 87.27800  28.59000  35.40100  1.000 368.76000 ? 243 THR B CA    1 
ATOM   5821 C  C     . THR B 2 243 ? 86.88300  27.14900  35.08400  1.000 366.86000 ? 243 THR B C     1 
ATOM   5822 O  O     . THR B 2 243 ? 85.72100  26.76400  35.26600  1.000 366.94000 ? 243 THR B O     1 
ATOM   5823 C  CB    . THR B 2 243 ? 87.28500  29.44800  34.13700  1.000 368.87000 ? 243 THR B CB    1 
ATOM   5824 O  OG1   . THR B 2 243 ? 88.56800  29.34100  33.49700  1.000 371.55000 ? 243 THR B OG1   1 
ATOM   5825 C  CG2   . THR B 2 243 ? 87.01300  30.90600  34.48400  1.000 370.41000 ? 243 THR B CG2   1 
ATOM   5826 N  N     . SER B 2 244 ? 87.83700  26.33400  34.62300  1.000 347.57000 ? 244 SER B N     1 
ATOM   5827 C  CA    . SER B 2 244 ? 87.57200  24.93900  34.28000  1.000 348.20000 ? 244 SER B CA    1 
ATOM   5828 C  C     . SER B 2 244 ? 87.04400  24.14100  35.46500  1.000 350.06000 ? 244 SER B C     1 
ATOM   5829 O  O     . SER B 2 244 ? 86.54400  23.01900  35.29700  1.000 345.60000 ? 244 SER B O     1 
ATOM   5830 C  CB    . SER B 2 244 ? 88.84200  24.29300  33.73700  1.000 353.15000 ? 244 SER B CB    1 
ATOM   5831 O  OG    . SER B 2 244 ? 89.99400  25.01700  34.13200  1.000 357.91000 ? 244 SER B OG    1 
ATOM   5832 N  N     . ASP B 2 245 ? 87.18100  24.72400  36.66200  1.000 378.21000 ? 245 ASP B N     1 
ATOM   5833 C  CA    . ASP B 2 245 ? 86.62300  24.24100  37.92200  1.000 386.77000 ? 245 ASP B CA    1 
ATOM   5834 C  C     . ASP B 2 245 ? 85.19900  24.75800  38.16600  1.000 388.58000 ? 245 ASP B C     1 
ATOM   5835 O  O     . ASP B 2 245 ? 84.36800  24.03600  38.71000  1.000 392.77000 ? 245 ASP B O     1 
ATOM   5836 C  CB    . ASP B 2 245 ? 87.50000  24.67100  39.12300  1.000 391.37000 ? 245 ASP B CB    1 
ATOM   5837 C  CG    . ASP B 2 245 ? 88.91900  24.07600  39.10100  1.000 390.96000 ? 245 ASP B CG    1 
ATOM   5838 O  OD1   . ASP B 2 245 ? 89.43000  23.70400  38.00400  1.000 392.45000 ? 245 ASP B OD1   1 
ATOM   5839 O  OD2   . ASP B 2 245 ? 89.54200  24.01800  40.19700  1.000 380.58000 ? 245 ASP B OD2   1 
ATOM   5840 N  N     . ILE B 2 246 ? 84.88600  26.00600  37.80000  1.000 385.11000 ? 246 ILE B N     1 
ATOM   5841 C  CA    . ILE B 2 246 ? 83.65700  26.64700  38.28600  1.000 375.59000 ? 246 ILE B CA    1 
ATOM   5842 C  C     . ILE B 2 246 ? 82.41800  25.95700  37.73700  1.000 376.86000 ? 246 ILE B C     1 
ATOM   5843 O  O     . ILE B 2 246 ? 81.43800  25.74100  38.46900  1.000 377.51000 ? 246 ILE B O     1 
ATOM   5844 C  CB    . ILE B 2 246 ? 83.63000  28.14100  37.93700  1.000 367.94000 ? 246 ILE B CB    1 
ATOM   5845 C  CG1   . ILE B 2 246 ? 84.96000  28.80100  38.21900  1.000 377.08000 ? 246 ILE B CG1   1 
ATOM   5846 C  CG2   . ILE B 2 246 ? 82.55700  28.77800  38.76200  1.000 355.29000 ? 246 ILE B CG2   1 
ATOM   5847 C  CD1   . ILE B 2 246 ? 85.23100  28.92800  39.67700  1.000 379.90000 ? 246 ILE B CD1   1 
ATOM   5848 N  N     . LEU B 2 247 ? 82.42900  25.62600  36.43700  1.000 373.50000 ? 247 LEU B N     1 
ATOM   5849 C  CA    . LEU B 2 247 ? 81.35800  24.81700  35.86000  1.000 375.99000 ? 247 LEU B CA    1 
ATOM   5850 C  C     . LEU B 2 247 ? 81.15800  23.52200  36.63500  1.000 386.32000 ? 247 LEU B C     1 
ATOM   5851 O  O     . LEU B 2 247 ? 80.01500  23.08900  36.84700  1.000 398.79000 ? 247 LEU B O     1 
ATOM   5852 C  CB    . LEU B 2 247 ? 81.66600  24.50600  34.38900  1.000 360.72000 ? 247 LEU B CB    1 
ATOM   5853 C  CG    . LEU B 2 247 ? 82.92700  23.76000  33.98200  1.000 356.22000 ? 247 LEU B CG    1 
ATOM   5854 C  CD1   . LEU B 2 247 ? 82.73200  22.23200  34.03000  1.000 356.28000 ? 247 LEU B CD1   1 
ATOM   5855 C  CD2   . LEU B 2 247 ? 83.18100  24.27200  32.59500  1.000 342.63000 ? 247 LEU B CD2   1 
ATOM   5856 N  N     . SER B 2 248 ? 82.25900  22.88800  37.06800  1.000 389.69000 ? 248 SER B N     1 
ATOM   5857 C  CA    . SER B 2 248 ? 82.15800  21.57000  37.70200  1.000 387.71000 ? 248 SER B CA    1 
ATOM   5858 C  C     . SER B 2 248 ? 81.45700  21.61600  39.06200  1.000 393.66000 ? 248 SER B C     1 
ATOM   5859 O  O     . SER B 2 248 ? 80.89100  20.60900  39.51100  1.000 389.34000 ? 248 SER B O     1 
ATOM   5860 C  CB    . SER B 2 248 ? 83.55300  20.97400  37.88700  1.000 373.70000 ? 248 SER B CB    1 
ATOM   5861 O  OG    . SER B 2 248 ? 83.80400  19.91700  36.99600  1.000 375.50000 ? 248 SER B OG    1 
ATOM   5862 N  N     . GLY B 2 249 ? 81.53500  22.75100  39.75800  1.000 399.21000 ? 249 GLY B N     1 
ATOM   5863 C  CA    . GLY B 2 249 ? 81.28300  22.80600  41.19100  1.000 393.61000 ? 249 GLY B CA    1 
ATOM   5864 C  C     . GLY B 2 249 ? 82.50300  22.59000  42.05300  1.000 393.07000 ? 249 GLY B C     1 
ATOM   5865 O  O     . GLY B 2 249 ? 82.38000  22.61800  43.29700  1.000 400.27000 ? 249 GLY B O     1 
ATOM   5866 N  N     . ARG B 2 250 ? 83.66400  22.33200  41.42700  1.000 388.72000 ? 250 ARG B N     1 
ATOM   5867 C  CA    . ARG B 2 250 ? 84.91100  22.16700  42.17100  1.000 381.88000 ? 250 ARG B CA    1 
ATOM   5868 C  C     . ARG B 2 250 ? 85.18700  23.36700  43.05500  1.000 377.79000 ? 250 ARG B C     1 
ATOM   5869 O  O     . ARG B 2 250 ? 85.74100  23.24100  44.15600  1.000 378.10000 ? 250 ARG B O     1 
ATOM   5870 C  CB    . ARG B 2 250 ? 86.07200  22.00800  41.19700  1.000 370.75000 ? 250 ARG B CB    1 
ATOM   5871 C  CG    . ARG B 2 250 ? 85.96000  20.80800  40.35300  1.000 371.06000 ? 250 ARG B CG    1 
ATOM   5872 C  CD    . ARG B 2 250 ? 86.73100  19.71500  40.98900  1.000 365.18000 ? 250 ARG B CD    1 
ATOM   5873 N  NE    . ARG B 2 250 ? 86.36000  18.43500  40.41600  1.000 367.43000 ? 250 ARG B NE    1 
ATOM   5874 C  CZ    . ARG B 2 250 ? 87.12000  17.35100  40.48600  1.000 368.07000 ? 250 ARG B CZ    1 
ATOM   5875 N  NH1   . ARG B 2 250 ? 88.29700  17.41200  41.09700  1.000 366.61000 ? 250 ARG B NH1   1 
ATOM   5876 N  NH2   . ARG B 2 250 ? 86.70600  16.21500  39.93800  1.000 365.98000 ? 250 ARG B NH2   1 
ATOM   5877 N  N     . TYR B 2 251 ? 84.84000  24.54900  42.56100  1.000 371.75000 ? 251 TYR B N     1 
ATOM   5878 C  CA    . TYR B 2 251 ? 84.93100  25.78900  43.33100  1.000 382.77000 ? 251 TYR B CA    1 
ATOM   5879 C  C     . TYR B 2 251 ? 83.67700  25.97700  44.17700  1.000 389.33000 ? 251 TYR B C     1 
ATOM   5880 O  O     . TYR B 2 251 ? 82.57500  26.15900  43.63900  1.000 385.80000 ? 251 TYR B O     1 
ATOM   5881 C  CB    . TYR B 2 251 ? 85.10500  27.01400  42.43600  1.000 382.05000 ? 251 TYR B CB    1 
ATOM   5882 C  CG    . TYR B 2 251 ? 85.17100  28.37600  43.18600  1.000 394.70000 ? 251 TYR B CG    1 
ATOM   5883 C  CD1   . TYR B 2 251 ? 84.03000  29.17200  43.36400  1.000 393.42000 ? 251 TYR B CD1   1 
ATOM   5884 C  CD2   . TYR B 2 251 ? 86.37400  28.85900  43.71700  1.000 390.78000 ? 251 TYR B CD2   1 
ATOM   5885 C  CE1   . TYR B 2 251 ? 84.07300  30.43200  44.06100  1.000 391.35000 ? 251 TYR B CE1   1 
ATOM   5886 C  CE2   . TYR B 2 251 ? 86.44700  30.12600  44.39700  1.000 387.68000 ? 251 TYR B CE2   1 
ATOM   5887 C  CZ    . TYR B 2 251 ? 85.27400  30.90600  44.56100  1.000 387.16000 ? 251 TYR B CZ    1 
ATOM   5888 O  OH    . TYR B 2 251 ? 85.27000  32.13100  45.21700  1.000 385.89000 ? 251 TYR B OH    1 
ATOM   5889 N  N     . ASP B 2 252 ? 83.86600  25.94500  45.50100  1.000 380.37000 ? 252 ASP B N     1 
ATOM   5890 C  CA    . ASP B 2 252 ? 82.91500  26.41700  46.50500  1.000 371.99000 ? 252 ASP B CA    1 
ATOM   5891 C  C     . ASP B 2 252 ? 83.73600  27.14000  47.56700  1.000 371.21000 ? 252 ASP B C     1 
ATOM   5892 O  O     . ASP B 2 252 ? 84.38300  26.48400  48.38900  1.000 373.04000 ? 252 ASP B O     1 
ATOM   5893 C  CB    . ASP B 2 252 ? 82.12200  25.25200  47.13600  1.000 371.00000 ? 252 ASP B CB    1 
ATOM   5894 C  CG    . ASP B 2 252 ? 81.14000  25.70700  48.23200  1.000 366.19000 ? 252 ASP B CG    1 
ATOM   5895 O  OD1   . ASP B 2 252 ? 79.94000  25.38300  48.14700  1.000 356.31000 ? 252 ASP B OD1   1 
ATOM   5896 O  OD2   . ASP B 2 252 ? 81.55200  26.40100  49.18500  1.000 369.61000 ? 252 ASP B OD2   1 
ATOM   5897 N  N     . THR B 2 253 ? 83.77000  28.47500  47.53600  1.000 372.65000 ? 253 THR B N     1 
ATOM   5898 C  CA    . THR B 2 253 ? 84.31800  29.21100  48.67100  1.000 375.14000 ? 253 THR B CA    1 
ATOM   5899 C  C     . THR B 2 253 ? 83.16700  29.53500  49.60200  1.000 382.57000 ? 253 THR B C     1 
ATOM   5900 O  O     . THR B 2 253 ? 82.09600  29.95400  49.14600  1.000 387.10000 ? 253 THR B O     1 
ATOM   5901 C  CB    . THR B 2 253 ? 85.08600  30.49300  48.29500  1.000 373.07000 ? 253 THR B CB    1 
ATOM   5902 O  OG1   . THR B 2 253 ? 84.43500  31.21000  47.23900  1.000 379.90000 ? 253 THR B OG1   1 
ATOM   5903 C  CG2   . THR B 2 253 ? 86.54600  30.22300  47.91200  1.000 373.36000 ? 253 THR B CG2   1 
ATOM   5904 N  N     . ASP B 2 254 ? 83.37000  29.28100  50.89800  1.000 391.81000 ? 254 ASP B N     1 
ATOM   5905 C  CA    . ASP B 2 254 ? 82.39200  29.74200  51.87000  1.000 391.44000 ? 254 ASP B CA    1 
ATOM   5906 C  C     . ASP B 2 254 ? 82.26200  31.26100  51.82500  1.000 396.43000 ? 254 ASP B C     1 
ATOM   5907 O  O     . ASP B 2 254 ? 81.23300  31.80900  52.25000  1.000 398.61000 ? 254 ASP B O     1 
ATOM   5908 C  CB    . ASP B 2 254 ? 82.80200  29.23800  53.26200  1.000 389.11000 ? 254 ASP B CB    1 
ATOM   5909 C  CG    . ASP B 2 254 ? 82.79200  27.72400  53.33200  1.000 386.05000 ? 254 ASP B CG    1 
ATOM   5910 O  OD1   . ASP B 2 254 ? 83.77400  27.11200  52.88000  1.000 395.02000 ? 254 ASP B OD1   1 
ATOM   5911 O  OD2   . ASP B 2 254 ? 81.78700  27.15100  53.79800  1.000 376.98000 ? 254 ASP B OD2   1 
ATOM   5912 N  N     . PHE B 2 255 ? 83.27200  31.96000  51.27400  1.000 397.27000 ? 255 PHE B N     1 
ATOM   5913 C  CA    . PHE B 2 255 ? 83.11300  33.39800  51.06700  1.000 397.09000 ? 255 PHE B CA    1 
ATOM   5914 C  C     . PHE B 2 255 ? 82.16500  33.67700  49.89600  1.000 395.98000 ? 255 PHE B C     1 
ATOM   5915 O  O     . PHE B 2 255 ? 81.25100  34.49700  50.02600  1.000 401.46000 ? 255 PHE B O     1 
ATOM   5916 C  CB    . PHE B 2 255 ? 84.49700  34.07500  50.94800  1.000 389.73000 ? 255 PHE B CB    1 
ATOM   5917 C  CG    . PHE B 2 255 ? 84.86100  34.66500  49.60100  1.000 378.07000 ? 255 PHE B CG    1 
ATOM   5918 C  CD1   . PHE B 2 255 ? 85.74900  34.00200  48.78900  1.000 372.78000 ? 255 PHE B CD1   1 
ATOM   5919 C  CD2   . PHE B 2 255 ? 84.46400  35.95200  49.21900  1.000 375.07000 ? 255 PHE B CD2   1 
ATOM   5920 C  CE1   . PHE B 2 255 ? 86.15700  34.53300  47.58200  1.000 367.63000 ? 255 PHE B CE1   1 
ATOM   5921 C  CE2   . PHE B 2 255 ? 84.88200  36.48600  47.99500  1.000 370.64000 ? 255 PHE B CE2   1 
ATOM   5922 C  CZ    . PHE B 2 255 ? 85.71900  35.76900  47.17600  1.000 368.25000 ? 255 PHE B CZ    1 
ATOM   5923 N  N     . ILE B 2 256 ? 82.30400  32.97500  48.76500  1.000 393.39000 ? 256 ILE B N     1 
ATOM   5924 C  CA    . ILE B 2 256 ? 81.26900  33.02000  47.72600  1.000 393.03000 ? 256 ILE B CA    1 
ATOM   5925 C  C     . ILE B 2 256 ? 81.13900  31.62400  47.09900  1.000 390.77000 ? 256 ILE B C     1 
ATOM   5926 O  O     . ILE B 2 256 ? 82.14700  30.97900  46.78100  1.000 390.91000 ? 256 ILE B O     1 
ATOM   5927 C  CB    . ILE B 2 256 ? 81.57400  34.07800  46.64300  1.000 383.05000 ? 256 ILE B CB    1 
ATOM   5928 C  CG1   . ILE B 2 256 ? 82.79700  33.66800  45.84900  1.000 376.62000 ? 256 ILE B CG1   1 
ATOM   5929 C  CG2   . ILE B 2 256 ? 81.80800  35.47100  47.25700  1.000 382.06000 ? 256 ILE B CG2   1 
ATOM   5930 C  CD1   . ILE B 2 256 ? 82.71500  33.87600  44.32100  1.000 374.74000 ? 256 ILE B CD1   1 
ATOM   5931 N  N     . ARG B 2 257 ? 79.90200  31.13100  46.97500  1.000 390.99000 ? 257 ARG B N     1 
ATOM   5932 C  CA    . ARG B 2 257 ? 79.59900  29.80700  46.44300  1.000 377.79000 ? 257 ARG B CA    1 
ATOM   5933 C  C     . ARG B 2 257 ? 79.54700  29.83100  44.91600  1.000 366.65000 ? 257 ARG B C     1 
ATOM   5934 O  O     . ARG B 2 257 ? 79.46600  30.89000  44.27400  1.000 364.20000 ? 257 ARG B O     1 
ATOM   5935 C  CB    . ARG B 2 257 ? 78.26200  29.30300  46.98800  1.000 368.77000 ? 257 ARG B CB    1 
ATOM   5936 C  CG    . ARG B 2 257 ? 78.26400  27.83200  47.24600  1.000 366.84000 ? 257 ARG B CG    1 
ATOM   5937 C  CD    . ARG B 2 257 ? 77.66700  27.58900  48.60000  1.000 370.14000 ? 257 ARG B CD    1 
ATOM   5938 N  NE    . ARG B 2 257 ? 78.12300  28.58000  49.56300  1.000 366.22000 ? 257 ARG B NE    1 
ATOM   5939 C  CZ    . ARG B 2 257 ? 77.40900  28.96700  50.61100  1.000 369.73000 ? 257 ARG B CZ    1 
ATOM   5940 N  NH1   . ARG B 2 257 ? 76.20700  28.44800  50.81700  1.000 371.66000 ? 257 ARG B NH1   1 
ATOM   5941 N  NH2   . ARG B 2 257 ? 77.89000  29.88300  51.44000  1.000 376.49000 ? 257 ARG B NH2   1 
ATOM   5942 N  N     . ASN B 2 258 ? 79.61500  28.63500  44.33100  1.000 358.87000 ? 258 ASN B N     1 
ATOM   5943 C  CA    . ASN B 2 258 ? 79.67500  28.56600  42.88200  1.000 351.86000 ? 258 ASN B CA    1 
ATOM   5944 C  C     . ASN B 2 258 ? 78.43100  29.17000  42.26800  1.000 348.22000 ? 258 ASN B C     1 
ATOM   5945 O  O     . ASN B 2 258 ? 78.51200  29.86400  41.24800  1.000 347.53000 ? 258 ASN B O     1 
ATOM   5946 C  CB    . ASN B 2 258 ? 79.85200  27.14400  42.41600  1.000 349.62000 ? 258 ASN B CB    1 
ATOM   5947 C  CG    . ASN B 2 258 ? 80.25300  27.08400  41.00800  1.000 352.12000 ? 258 ASN B CG    1 
ATOM   5948 O  OD1   . ASN B 2 258 ? 80.12000  28.05100  40.28700  1.000 350.84000 ? 258 ASN B OD1   1 
ATOM   5949 N  ND2   . ASN B 2 258 ? 80.76900  25.95800  40.59800  1.000 348.04000 ? 258 ASN B ND2   1 
ATOM   5950 N  N     . TYR B 2 259 ? 77.27700  28.97000  42.91900  1.000 364.88000 ? 259 TYR B N     1 
ATOM   5951 C  CA    . TYR B 2 259 ? 76.01700  29.51600  42.42600  1.000 369.71000 ? 259 TYR B CA    1 
ATOM   5952 C  C     . TYR B 2 259 ? 76.16500  31.02000  42.26600  1.000 366.76000 ? 259 TYR B C     1 
ATOM   5953 O  O     . TYR B 2 259 ? 75.61200  31.62100  41.33900  1.000 368.70000 ? 259 TYR B O     1 
ATOM   5954 C  CB    . TYR B 2 259 ? 74.83500  29.15300  43.34900  1.000 367.83000 ? 259 TYR B CB    1 
ATOM   5955 C  CG    . TYR B 2 259 ? 74.73500  29.86700  44.70100  1.000 364.41000 ? 259 TYR B CG    1 
ATOM   5956 C  CD1   . TYR B 2 259 ? 74.97100  29.19100  45.90000  1.000 363.72000 ? 259 TYR B CD1   1 
ATOM   5957 C  CD2   . TYR B 2 259 ? 74.34700  31.20000  44.78200  1.000 364.66000 ? 259 TYR B CD2   1 
ATOM   5958 C  CE1   . TYR B 2 259 ? 74.86000  29.84600  47.14400  1.000 361.48000 ? 259 TYR B CE1   1 
ATOM   5959 C  CE2   . TYR B 2 259 ? 74.23900  31.86100  46.01100  1.000 365.67000 ? 259 TYR B CE2   1 
ATOM   5960 C  CZ    . TYR B 2 259 ? 74.49400  31.18000  47.19200  1.000 359.18000 ? 259 TYR B CZ    1 
ATOM   5961 O  OH    . TYR B 2 259 ? 74.38500  31.83200  48.41100  1.000 355.25000 ? 259 TYR B OH    1 
ATOM   5962 N  N     . GLU B 2 260 ? 76.93000  31.63300  43.16500  1.000 363.64000 ? 260 GLU B N     1 
ATOM   5963 C  CA    . GLU B 2 260 ? 77.25000  33.03500  42.97800  1.000 359.91000 ? 260 GLU B CA    1 
ATOM   5964 C  C     . GLU B 2 260 ? 78.10900  33.20800  41.73700  1.000 362.07000 ? 260 GLU B C     1 
ATOM   5965 O  O     . GLU B 2 260 ? 77.86200  34.10100  40.92000  1.000 367.65000 ? 260 GLU B O     1 
ATOM   5966 C  CB    . GLU B 2 260 ? 77.94000  33.59300  44.21600  1.000 362.97000 ? 260 GLU B CB    1 
ATOM   5967 C  CG    . GLU B 2 260 ? 77.69900  35.06400  44.44500  1.000 366.24000 ? 260 GLU B CG    1 
ATOM   5968 C  CD    . GLU B 2 260 ? 76.22100  35.42500  44.44400  1.000 361.53000 ? 260 GLU B CD    1 
ATOM   5969 O  OE1   . GLU B 2 260 ? 75.70200  35.85600  43.39400  1.000 355.51000 ? 260 GLU B OE1   1 
ATOM   5970 O  OE2   . GLU B 2 260 ? 75.57600  35.28300  45.49900  1.000 368.20000 ? 260 GLU B OE2   1 
ATOM   5971 N  N     . CYS B 2 261 ? 79.08200  32.31300  41.54000  1.000 361.28000 ? 261 CYS B N     1 
ATOM   5972 C  CA    . CYS B 2 261 ? 80.03600  32.51200  40.45400  1.000 359.40000 ? 261 CYS B CA    1 
ATOM   5973 C  C     . CYS B 2 261 ? 79.39300  32.29200  39.09400  1.000 352.61000 ? 261 CYS B C     1 
ATOM   5974 O  O     . CYS B 2 261 ? 79.67700  33.02700  38.13300  1.000 343.78000 ? 261 CYS B O     1 
ATOM   5975 C  CB    . CYS B 2 261 ? 81.23600  31.58900  40.61000  1.000 356.84000 ? 261 CYS B CB    1 
ATOM   5976 S  SG    . CYS B 2 261 ? 82.43600  31.97700  39.31900  1.000 373.79000 ? 261 CYS B SG    1 
ATOM   5977 N  N     . GLN B 2 262 ? 78.53200  31.27500  38.99500  1.000 356.49000 ? 262 GLN B N     1 
ATOM   5978 C  CA    . GLN B 2 262 ? 77.85900  30.98800  37.73400  1.000 350.77000 ? 262 GLN B CA    1 
ATOM   5979 C  C     . GLN B 2 262 ? 76.98800  32.15100  37.29200  1.000 344.79000 ? 262 GLN B C     1 
ATOM   5980 O  O     . GLN B 2 262 ? 77.03000  32.55000  36.11900  1.000 335.96000 ? 262 GLN B O     1 
ATOM   5981 C  CB    . GLN B 2 262 ? 77.02200  29.71600  37.87500  1.000 356.11000 ? 262 GLN B CB    1 
ATOM   5982 C  CG    . GLN B 2 262 ? 77.74000  28.64200  38.63900  1.000 355.81000 ? 262 GLN B CG    1 
ATOM   5983 C  CD    . GLN B 2 262 ? 77.40600  27.24100  38.18600  1.000 351.56000 ? 262 GLN B CD    1 
ATOM   5984 O  OE1   . GLN B 2 262 ? 76.24500  26.82400  38.17600  1.000 345.64000 ? 262 GLN B OE1   1 
ATOM   5985 N  NE2   . GLN B 2 262 ? 78.43600  26.49400  37.82100  1.000 358.39000 ? 262 GLN B NE2   1 
ATOM   5986 N  N     . ARG B 2 263 ? 76.20600  32.71700  38.22200  1.000 345.35000 ? 263 ARG B N     1 
ATOM   5987 C  CA    . ARG B 2 263 ? 75.42400  33.89900  37.89000  1.000 341.62000 ? 263 ARG B CA    1 
ATOM   5988 C  C     . ARG B 2 263 ? 76.32300  34.99900  37.35900  1.000 335.87000 ? 263 ARG B C     1 
ATOM   5989 O  O     . ARG B 2 263 ? 75.92600  35.74400  36.46500  1.000 333.51000 ? 263 ARG B O     1 
ATOM   5990 C  CB    . ARG B 2 263 ? 74.63200  34.38700  39.10800  1.000 347.02000 ? 263 ARG B CB    1 
ATOM   5991 C  CG    . ARG B 2 263 ? 74.08100  35.82500  38.99300  1.000 347.50000 ? 263 ARG B CG    1 
ATOM   5992 C  CD    . ARG B 2 263 ? 72.89100  36.12400  39.93000  1.000 354.16000 ? 263 ARG B CD    1 
ATOM   5993 N  NE    . ARG B 2 263 ? 73.10500  35.67500  41.30700  1.000 362.52000 ? 263 ARG B NE    1 
ATOM   5994 C  CZ    . ARG B 2 263 ? 72.67200  34.51300  41.79100  1.000 356.66000 ? 263 ARG B CZ    1 
ATOM   5995 N  NH1   . ARG B 2 263 ? 72.00200  33.67800  41.01000  1.000 346.72000 ? 263 ARG B NH1   1 
ATOM   5996 N  NH2   . ARG B 2 263 ? 72.91700  34.18200  43.04800  1.000 352.00000 ? 263 ARG B NH2   1 
ATOM   5997 N  N     . LEU B 2 264 ? 77.56200  35.07500  37.85200  1.000 337.59000 ? 264 LEU B N     1 
ATOM   5998 C  CA    . LEU B 2 264 ? 78.41100  36.22900  37.54600  1.000 330.39000 ? 264 LEU B CA    1 
ATOM   5999 C  C     . LEU B 2 264 ? 78.93600  36.21300  36.12000  1.000 327.43000 ? 264 LEU B C     1 
ATOM   6000 O  O     . LEU B 2 264 ? 79.18500  37.27400  35.53500  1.000 330.08000 ? 264 LEU B O     1 
ATOM   6001 C  CB    . LEU B 2 264 ? 79.57100  36.30700  38.52100  1.000 339.51000 ? 264 LEU B CB    1 
ATOM   6002 C  CG    . LEU B 2 264 ? 79.15700  36.84000  39.88500  1.000 361.27000 ? 264 LEU B CG    1 
ATOM   6003 C  CD1   . LEU B 2 264 ? 80.34300  36.77100  40.82800  1.000 378.90000 ? 264 LEU B CD1   1 
ATOM   6004 C  CD2   . LEU B 2 264 ? 78.63000  38.27000  39.75800  1.000 354.99000 ? 264 LEU B CD2   1 
ATOM   6005 N  N     . ILE B 2 265 ? 79.07400  35.02200  35.54200  1.000 314.97000 ? 265 ILE B N     1 
ATOM   6006 C  CA    . ILE B 2 265 ? 79.60900  34.87600  34.19400  1.000 312.55000 ? 265 ILE B CA    1 
ATOM   6007 C  C     . ILE B 2 265 ? 78.64100  35.44700  33.17300  1.000 309.58000 ? 265 ILE B C     1 
ATOM   6008 O  O     . ILE B 2 265 ? 79.03700  35.88200  32.08300  1.000 308.89000 ? 265 ILE B O     1 
ATOM   6009 C  CB    . ILE B 2 265 ? 79.89100  33.39100  33.92700  1.000 309.62000 ? 265 ILE B CB    1 
ATOM   6010 C  CG1   . ILE B 2 265 ? 80.87100  32.85300  34.94900  1.000 305.51000 ? 265 ILE B CG1   1 
ATOM   6011 C  CG2   . ILE B 2 265 ? 80.47900  33.20800  32.57700  1.000 310.89000 ? 265 ILE B CG2   1 
ATOM   6012 C  CD1   . ILE B 2 265 ? 81.17500  31.41700  34.71700  1.000 292.67000 ? 265 ILE B CD1   1 
ATOM   6013 N  N     . VAL B 2 266 ? 77.35700  35.48200  33.52800  1.000 325.08000 ? 266 VAL B N     1 
ATOM   6014 C  CA    . VAL B 2 266 ? 76.31400  35.67000  32.52900  1.000 328.69000 ? 266 VAL B CA    1 
ATOM   6015 C  C     . VAL B 2 266 ? 76.23900  37.13000  32.10600  1.000 328.91000 ? 266 VAL B C     1 
ATOM   6016 O  O     . VAL B 2 266 ? 76.35300  37.43900  30.90900  1.000 325.34000 ? 266 VAL B O     1 
ATOM   6017 C  CB    . VAL B 2 266 ? 74.96600  35.14600  33.06700  1.000 336.18000 ? 266 VAL B CB    1 
ATOM   6018 C  CG1   . VAL B 2 266 ? 73.90800  35.18600  32.00100  1.000 331.12000 ? 266 VAL B CG1   1 
ATOM   6019 C  CG2   . VAL B 2 266 ? 75.11400  33.79300  33.73100  1.000 336.82000 ? 266 VAL B CG2   1 
ATOM   6020 N  N     . GLN B 2 267 ? 76.02400  38.04200  33.07400  1.000 330.97000 ? 267 GLN B N     1 
ATOM   6021 C  CA    . GLN B 2 267 ? 76.08100  39.47900  32.80800  1.000 334.09000 ? 267 GLN B CA    1 
ATOM   6022 C  C     . GLN B 2 267 ? 77.24700  39.79500  31.86300  1.000 331.83000 ? 267 GLN B C     1 
ATOM   6023 O  O     . GLN B 2 267 ? 77.07500  40.50100  30.86400  1.000 328.67000 ? 267 GLN B O     1 
ATOM   6024 C  CB    . GLN B 2 267 ? 76.18300  40.26100  34.16100  1.000 339.18000 ? 267 GLN B CB    1 
ATOM   6025 C  CG    . GLN B 2 267 ? 75.19000  39.84600  35.36100  1.000 331.99000 ? 267 GLN B CG    1 
ATOM   6026 C  CD    . GLN B 2 267 ? 75.76700  38.71700  36.19100  1.000 333.06000 ? 267 GLN B CD    1 
ATOM   6027 O  OE1   . GLN B 2 267 ? 76.38900  37.83100  35.62700  1.000 331.57000 ? 267 GLN B OE1   1 
ATOM   6028 N  NE2   . GLN B 2 267 ? 75.64300  38.77700  37.51900  1.000 333.32000 ? 267 GLN B NE2   1 
ATOM   6029 N  N     . LEU B 2 268 ? 78.41700  39.18600  32.11800  1.000 334.68000 ? 268 LEU B N     1 
ATOM   6030 C  CA    . LEU B 2 268 ? 79.61500  39.36800  31.28600  1.000 325.00000 ? 268 LEU B CA    1 
ATOM   6031 C  C     . LEU B 2 268 ? 79.40100  38.87100  29.87000  1.000 317.13000 ? 268 LEU B C     1 
ATOM   6032 O  O     . LEU B 2 268 ? 79.61200  39.59900  28.89100  1.000 317.43000 ? 268 LEU B O     1 
ATOM   6033 C  CB    . LEU B 2 268 ? 80.78500  38.59300  31.87300  1.000 333.58000 ? 268 LEU B CB    1 
ATOM   6034 C  CG    . LEU B 2 268 ? 81.22300  39.06800  33.25400  1.000 358.59000 ? 268 LEU B CG    1 
ATOM   6035 C  CD1   . LEU B 2 268 ? 81.96400  37.97800  34.06700  1.000 363.57000 ? 268 LEU B CD1   1 
ATOM   6036 C  CD2   . LEU B 2 268 ? 82.00200  40.46700  33.28700  1.000 363.58000 ? 268 LEU B CD2   1 
ATOM   6037 N  N     . ILE B 2 269 ? 79.07800  37.58900  29.75900  1.000 316.64000 ? 269 ILE B N     1 
ATOM   6038 C  CA    . ILE B 2 269 ? 78.69600  36.98700  28.49500  1.000 319.44000 ? 269 ILE B CA    1 
ATOM   6039 C  C     . ILE B 2 269 ? 77.71800  37.89300  27.76400  1.000 331.00000 ? 269 ILE B C     1 
ATOM   6040 O  O     . ILE B 2 269 ? 77.98400  38.34600  26.63900  1.000 330.47000 ? 269 ILE B O     1 
ATOM   6041 C  CB    . ILE B 2 269 ? 78.10600  35.59400  28.77200  1.000 319.47000 ? 269 ILE B CB    1 
ATOM   6042 C  CG1   . ILE B 2 269 ? 79.11500  34.75100  29.55400  1.000 310.02000 ? 269 ILE B CG1   1 
ATOM   6043 C  CG2   . ILE B 2 269 ? 77.72700  34.88500  27.50100  1.000 320.32000 ? 269 ILE B CG2   1 
ATOM   6044 C  CD1   . ILE B 2 269 ? 78.71200  33.30900  29.74200  1.000 314.16000 ? 269 ILE B CD1   1 
ATOM   6045 N  N     . ASN B 2 270 ? 76.58900  38.21500  28.41800  1.000 338.99000 ? 270 ASN B N     1 
ATOM   6046 C  CA    . ASN B 2 270 ? 75.56800  39.03300  27.75600  1.000 339.04000 ? 270 ASN B CA    1 
ATOM   6047 C  C     . ASN B 2 270 ? 76.10900  40.42800  27.46100  1.000 339.17000 ? 270 ASN B C     1 
ATOM   6048 O  O     . ASN B 2 270 ? 75.76500  41.02900  26.42700  1.000 340.51000 ? 270 ASN B O     1 
ATOM   6049 C  CB    . ASN B 2 270 ? 74.28700  39.13400  28.60700  1.000 331.90000 ? 270 ASN B CB    1 
ATOM   6050 C  CG    . ASN B 2 270 ? 73.62600  37.77100  28.88000  1.000 320.88000 ? 270 ASN B CG    1 
ATOM   6051 O  OD1   . ASN B 2 270 ? 72.46700  37.53500  28.50500  1.000 307.53000 ? 270 ASN B OD1   1 
ATOM   6052 N  ND2   . ASN B 2 270 ? 74.33700  36.89900  29.57800  1.000 325.23000 ? 270 ASN B ND2   1 
ATOM   6053 N  N     . LYS B 2 271 ? 76.97300  40.94700  28.35800  1.000 340.68000 ? 271 LYS B N     1 
ATOM   6054 C  CA    . LYS B 2 271 ? 77.67200  42.20200  28.09600  1.000 337.07000 ? 271 LYS B CA    1 
ATOM   6055 C  C     . LYS B 2 271 ? 78.69800  42.02200  26.98700  1.000 333.46000 ? 271 LYS B C     1 
ATOM   6056 O  O     . LYS B 2 271 ? 78.70200  42.79000  26.01100  1.000 335.10000 ? 271 LYS B O     1 
ATOM   6057 C  CB    . LYS B 2 271 ? 78.33000  42.70100  29.39500  1.000 331.42000 ? 271 LYS B CB    1 
ATOM   6058 C  CG    . LYS B 2 271 ? 78.66500  44.20500  29.51100  1.000 334.12000 ? 271 LYS B CG    1 
ATOM   6059 C  CD    . LYS B 2 271 ? 77.52600  45.11600  29.06300  1.000 338.85000 ? 271 LYS B CD    1 
ATOM   6060 C  CE    . LYS B 2 271 ? 77.96300  46.58200  29.03200  1.000 348.04000 ? 271 LYS B CE    1 
ATOM   6061 N  NZ    . LYS B 2 271 ? 76.81500  47.46900  28.67500  1.000 351.63000 ? 271 LYS B NZ    1 
ATOM   6062 N  N     . ALA B 2 272 ? 79.55500  40.99300  27.10100  1.000 317.25000 ? 272 ALA B N     1 
ATOM   6063 C  CA    . ALA B 2 272 ? 80.47300  40.70100  26.00800  1.000 317.19000 ? 272 ALA B CA    1 
ATOM   6064 C  C     . ALA B 2 272 ? 79.73500  40.70900  24.69100  1.000 315.09000 ? 272 ALA B C     1 
ATOM   6065 O  O     . ALA B 2 272 ? 80.20500  41.29200  23.71100  1.000 312.65000 ? 272 ALA B O     1 
ATOM   6066 C  CB    . ALA B 2 272 ? 81.13700  39.34400  26.21900  1.000 313.69000 ? 272 ALA B CB    1 
ATOM   6067 N  N     . PHE B 2 273 ? 78.54100  40.11200  24.68200  1.000 321.61000 ? 273 PHE B N     1 
ATOM   6068 C  CA    . PHE B 2 273 ? 77.66000  40.21100  23.53100  1.000 324.64000 ? 273 PHE B CA    1 
ATOM   6069 C  C     . PHE B 2 273 ? 77.29700  41.65500  23.26200  1.000 326.10000 ? 273 PHE B C     1 
ATOM   6070 O  O     . PHE B 2 273 ? 77.58200  42.17900  22.17500  1.000 323.75000 ? 273 PHE B O     1 
ATOM   6071 C  CB    . PHE B 2 273 ? 76.39800  39.37600  23.73900  1.000 332.05000 ? 273 PHE B CB    1 
ATOM   6072 C  CG    . PHE B 2 273 ? 75.81500  38.83200  22.45100  1.000 335.01000 ? 273 PHE B CG    1 
ATOM   6073 C  CD1   . PHE B 2 273 ? 74.70900  39.41200  21.84400  1.000 331.21000 ? 273 PHE B CD1   1 
ATOM   6074 C  CD2   . PHE B 2 273 ? 76.37900  37.71700  21.85200  1.000 339.96000 ? 273 PHE B CD2   1 
ATOM   6075 C  CE1   . PHE B 2 273 ? 74.17700  38.88300  20.66800  1.000 325.48000 ? 273 PHE B CE1   1 
ATOM   6076 C  CE2   . PHE B 2 273 ? 75.86400  37.19200  20.67500  1.000 332.06000 ? 273 PHE B CE2   1 
ATOM   6077 C  CZ    . PHE B 2 273 ? 74.75800  37.76700  20.08600  1.000 321.24000 ? 273 PHE B CZ    1 
ATOM   6078 N  N     . GLU B 2 274 ? 76.69600  42.32800  24.25300  1.000 327.81000 ? 274 GLU B N     1 
ATOM   6079 C  CA    . GLU B 2 274 ? 76.16500  43.67100  24.01500  1.000 326.51000 ? 274 GLU B CA    1 
ATOM   6080 C  C     . GLU B 2 274 ? 77.24200  44.61100  23.48300  1.000 324.69000 ? 274 GLU B C     1 
ATOM   6081 O  O     . GLU B 2 274 ? 76.94900  45.56100  22.74200  1.000 326.61000 ? 274 GLU B O     1 
ATOM   6082 C  CB    . GLU B 2 274 ? 75.57500  44.25900  25.29900  1.000 332.86000 ? 274 GLU B CB    1 
ATOM   6083 C  CG    . GLU B 2 274 ? 74.09300  43.98700  25.55200  1.000 332.75000 ? 274 GLU B CG    1 
ATOM   6084 C  CD    . GLU B 2 274 ? 73.57300  44.67700  26.82200  1.000 331.24000 ? 274 GLU B CD    1 
ATOM   6085 O  OE1   . GLU B 2 274 ? 72.34000  44.85500  26.95700  1.000 332.81000 ? 274 GLU B OE1   1 
ATOM   6086 O  OE2   . GLU B 2 274 ? 74.39400  45.04500  27.68800  1.000 332.96000 ? 274 GLU B OE2   1 
ATOM   6087 N  N     . LEU B 2 275 ? 78.49500  44.37500  23.86900  1.000 326.90000 ? 275 LEU B N     1 
ATOM   6088 C  CA    . LEU B 2 275 ? 79.57600  45.21100  23.36400  1.000 329.60000 ? 275 LEU B CA    1 
ATOM   6089 C  C     . LEU B 2 275 ? 79.96500  44.79600  21.97100  1.000 330.02000 ? 275 LEU B C     1 
ATOM   6090 O  O     . LEU B 2 275 ? 80.27000  45.64300  21.12000  1.000 338.23000 ? 275 LEU B O     1 
ATOM   6091 C  CB    . LEU B 2 275 ? 80.79500  45.11700  24.25300  1.000 331.34000 ? 275 LEU B CB    1 
ATOM   6092 C  CG    . LEU B 2 275 ? 80.66400  45.90800  25.52100  1.000 347.88000 ? 275 LEU B CG    1 
ATOM   6093 C  CD1   . LEU B 2 275 ? 81.98100  45.76100  26.17900  1.000 360.56000 ? 275 LEU B CD1   1 
ATOM   6094 C  CD2   . LEU B 2 275 ? 80.32900  47.37100  25.22300  1.000 341.62000 ? 275 LEU B CD2   1 
ATOM   6095 N  N     . ARG B 2 276 ? 79.99300  43.48300  21.73800  1.000 322.01000 ? 276 ARG B N     1 
ATOM   6096 C  CA    . ARG B 2 276 ? 80.37700  42.98800  20.42900  1.000 329.66000 ? 276 ARG B CA    1 
ATOM   6097 C  C     . ARG B 2 276 ? 79.46200  43.54300  19.34900  1.000 335.16000 ? 276 ARG B C     1 
ATOM   6098 O  O     . ARG B 2 276 ? 79.91700  43.83900  18.23400  1.000 336.57000 ? 276 ARG B O     1 
ATOM   6099 C  CB    . ARG B 2 276 ? 80.35300  41.45100  20.41000  1.000 325.90000 ? 276 ARG B CB    1 
ATOM   6100 C  CG    . ARG B 2 276 ? 81.16000  40.89900  19.24100  1.000 324.31000 ? 276 ARG B CG    1 
ATOM   6101 C  CD    . ARG B 2 276 ? 82.63600  41.21400  19.39400  1.000 323.87000 ? 276 ARG B CD    1 
ATOM   6102 N  NE    . ARG B 2 276 ? 83.41300  40.65500  18.25600  1.000 315.50000 ? 276 ARG B NE    1 
ATOM   6103 C  CZ    . ARG B 2 276 ? 84.01600  41.31900  17.26600  1.000 317.80000 ? 276 ARG B CZ    1 
ATOM   6104 N  NH1   . ARG B 2 276 ? 84.07700  42.64300  17.16400  1.000 314.06000 ? 276 ARG B NH1   1 
ATOM   6105 N  NH2   . ARG B 2 276 ? 84.62900  40.58600  16.38600  1.000 322.76000 ? 276 ARG B NH2   1 
ATOM   6106 N  N     . MET B 2 277 ? 78.16800  43.69500  19.67000  1.000 339.08000 ? 277 MET B N     1 
ATOM   6107 C  CA    . MET B 2 277 ? 77.18600  44.17900  18.71400  1.000 339.88000 ? 277 MET B CA    1 
ATOM   6108 C  C     . MET B 2 277 ? 77.24700  45.69300  18.56400  1.000 344.80000 ? 277 MET B C     1 
ATOM   6109 O  O     . MET B 2 277 ? 76.64600  46.23500  17.61300  1.000 339.87000 ? 277 MET B O     1 
ATOM   6110 C  CB    . MET B 2 277 ? 75.78900  43.69200  19.13300  1.000 330.73000 ? 277 MET B CB    1 
ATOM   6111 C  CG    . MET B 2 277 ? 75.66400  42.16500  19.38900  1.000 319.41000 ? 277 MET B CG    1 
ATOM   6112 S  SD    . MET B 2 277 ? 75.31900  41.09700  17.95200  1.000 312.34000 ? 277 MET B SD    1 
ATOM   6113 C  CE    . MET B 2 277 ? 76.60300  39.85400  18.16100  1.000 307.55000 ? 277 MET B CE    1 
ATOM   6114 N  N     . LYS B 2 278 ? 77.96200  46.37000  19.47700  1.000 347.01000 ? 278 LYS B N     1 
ATOM   6115 C  CA    . LYS B 2 278 ? 78.31400  47.76500  19.25200  1.000 348.72000 ? 278 LYS B CA    1 
ATOM   6116 C  C     . LYS B 2 278 ? 79.08600  47.91800  17.94900  1.000 341.07000 ? 278 LYS B C     1 
ATOM   6117 O  O     . LYS B 2 278 ? 78.98100  48.94400  17.26400  1.000 337.10000 ? 278 LYS B O     1 
ATOM   6118 C  CB    . LYS B 2 278 ? 79.13800  48.28100  20.43600  1.000 339.83000 ? 278 LYS B CB    1 
ATOM   6119 C  CG    . LYS B 2 278 ? 78.93600  49.73300  20.76300  1.000 334.15000 ? 278 LYS B CG    1 
ATOM   6120 C  CD    . LYS B 2 278 ? 79.09500  49.96500  22.24100  1.000 337.10000 ? 278 LYS B CD    1 
ATOM   6121 C  CE    . LYS B 2 278 ? 78.34600  51.21800  22.63200  1.000 322.86000 ? 278 LYS B CE    1 
ATOM   6122 N  NZ    . LYS B 2 278 ? 78.65600  51.58100  24.02700  1.000 325.56000 ? 278 LYS B NZ    1 
ATOM   6123 N  N     . ASP B 2 279 ? 79.83300  46.88000  17.57400  1.000 334.83000 ? 279 ASP B N     1 
ATOM   6124 C  CA    . ASP B 2 279 ? 80.70200  46.89600  16.40300  1.000 330.83000 ? 279 ASP B CA    1 
ATOM   6125 C  C     . ASP B 2 279 ? 80.67100  45.53100  15.71400  1.000 328.00000 ? 279 ASP B C     1 
ATOM   6126 O  O     . ASP B 2 279 ? 81.65100  44.78400  15.73700  1.000 324.18000 ? 279 ASP B O     1 
ATOM   6127 C  CB    . ASP B 2 279 ? 82.13700  47.25800  16.78700  1.000 333.27000 ? 279 ASP B CB    1 
ATOM   6128 C  CG    . ASP B 2 279 ? 83.00800  47.56000  15.57100  1.000 343.47000 ? 279 ASP B CG    1 
ATOM   6129 O  OD1   . ASP B 2 279 ? 83.06700  48.73900  15.16200  1.000 347.59000 ? 279 ASP B OD1   1 
ATOM   6130 O  OD2   . ASP B 2 279 ? 83.64000  46.62300  15.03900  1.000 346.74000 ? 279 ASP B OD2   1 
ATOM   6131 N  N     . LYS B 2 280 ? 79.52100  45.20600  15.10000  1.000 322.60000 ? 280 LYS B N     1 
ATOM   6132 C  CA    . LYS B 2 280 ? 79.35700  44.01500  14.26900  1.000 326.83000 ? 280 LYS B CA    1 
ATOM   6133 C  C     . LYS B 2 280 ? 78.22500  44.16700  13.24800  1.000 323.61000 ? 280 LYS B C     1 
ATOM   6134 O  O     . LYS B 2 280 ? 77.67900  43.15700  12.79600  1.000 325.44000 ? 280 LYS B O     1 
ATOM   6135 C  CB    . LYS B 2 280 ? 79.16400  42.77800  15.18200  1.000 331.58000 ? 280 LYS B CB    1 
ATOM   6136 C  CG    . LYS B 2 280 ? 79.41300  41.39400  14.54000  1.000 326.05000 ? 280 LYS B CG    1 
ATOM   6137 C  CD    . LYS B 2 280 ? 80.52400  41.38400  13.49300  1.000 318.04000 ? 280 LYS B CD    1 
ATOM   6138 C  CE    . LYS B 2 280 ? 79.98600  41.06200  12.10100  1.000 317.27000 ? 280 LYS B CE    1 
ATOM   6139 N  NZ    . LYS B 2 280 ? 81.06300  40.48600  11.27000  1.000 297.07000 ? 280 LYS B NZ    1 
ATOM   6140 N  N     . ASN B 2 281 ? 77.85800  45.40300  12.90100  1.000 310.52000 ? 281 ASN B N     1 
ATOM   6141 C  CA    . ASN B 2 281 ? 77.07400  45.75800  11.71300  1.000 314.54000 ? 281 ASN B CA    1 
ATOM   6142 C  C     . ASN B 2 281 ? 75.56400  45.65300  11.86400  1.000 311.97000 ? 281 ASN B C     1 
ATOM   6143 O  O     . ASN B 2 281 ? 74.88400  45.50500  10.84600  1.000 310.16000 ? 281 ASN B O     1 
ATOM   6144 C  CB    . ASN B 2 281 ? 77.44400  44.88700  10.51100  1.000 309.80000 ? 281 ASN B CB    1 
ATOM   6145 C  CG    . ASN B 2 281 ? 78.13000  45.66000  9.42100   1.000 322.52000 ? 281 ASN B CG    1 
ATOM   6146 O  OD1   . ASN B 2 281 ? 78.52300  46.81700  9.58900   1.000 317.62000 ? 281 ASN B OD1   1 
ATOM   6147 N  ND2   . ASN B 2 281 ? 78.29700  45.01800  8.29300   1.000 328.26000 ? 281 ASN B ND2   1 
ATOM   6148 N  N     . VAL B 2 282 ? 74.99700  45.70800  13.06400  1.000 325.91000 ? 282 VAL B N     1 
ATOM   6149 C  CA    . VAL B 2 282 ? 73.54700  45.60300  13.21400  1.000 322.18000 ? 282 VAL B CA    1 
ATOM   6150 C  C     . VAL B 2 282 ? 73.03500  46.70300  14.13800  1.000 320.05000 ? 282 VAL B C     1 
ATOM   6151 O  O     . VAL B 2 282 ? 73.58700  46.91600  15.22500  1.000 314.55000 ? 282 VAL B O     1 
ATOM   6152 C  CB    . VAL B 2 282 ? 73.12100  44.21100  13.72200  1.000 316.47000 ? 282 VAL B CB    1 
ATOM   6153 C  CG1   . VAL B 2 282 ? 73.56400  43.14500  12.72700  1.000 312.24000 ? 282 VAL B CG1   1 
ATOM   6154 C  CG2   . VAL B 2 282 ? 73.67100  43.93800  15.11500  1.000 313.75000 ? 282 VAL B CG2   1 
ATOM   6155 N  N     . ARG B 2 283 ? 72.01700  47.43200  13.67500  1.000 311.39000 ? 283 ARG B N     1 
ATOM   6156 C  CA    . ARG B 2 283 ? 71.31500  48.36900  14.53200  1.000 302.39000 ? 283 ARG B CA    1 
ATOM   6157 C  C     . ARG B 2 283 ? 70.56200  47.59000  15.59800  1.000 303.90000 ? 283 ARG B C     1 
ATOM   6158 O  O     . ARG B 2 283 ? 70.08200  46.48600  15.35600  1.000 304.11000 ? 283 ARG B O     1 
ATOM   6159 C  CB    . ARG B 2 283 ? 70.34300  49.21000  13.70700  1.000 300.44000 ? 283 ARG B CB    1 
ATOM   6160 C  CG    . ARG B 2 283 ? 69.80200  50.42500  14.43600  1.000 302.37000 ? 283 ARG B CG    1 
ATOM   6161 C  CD    . ARG B 2 283 ? 70.93900  51.38400  14.67600  1.000 321.18000 ? 283 ARG B CD    1 
ATOM   6162 N  NE    . ARG B 2 283 ? 70.57800  52.44700  15.60000  1.000 335.08000 ? 283 ARG B NE    1 
ATOM   6163 C  CZ    . ARG B 2 283 ? 71.46000  53.15800  16.29500  1.000 332.73000 ? 283 ARG B CZ    1 
ATOM   6164 N  NH1   . ARG B 2 283 ? 72.75700  52.91300  16.17400  1.000 328.77000 ? 283 ARG B NH1   1 
ATOM   6165 N  NH2   . ARG B 2 283 ? 71.04400  54.10800  17.12100  1.000 344.18000 ? 283 ARG B NH2   1 
ATOM   6166 N  N     . GLU B 2 284 ? 70.45500  48.15600  16.78900  1.000 314.29000 ? 284 GLU B N     1 
ATOM   6167 C  CA    . GLU B 2 284 ? 69.95100  47.42100  17.94900  1.000 315.37000 ? 284 GLU B CA    1 
ATOM   6168 C  C     . GLU B 2 284 ? 68.54900  47.89700  18.32200  1.000 324.07000 ? 284 GLU B C     1 
ATOM   6169 O  O     . GLU B 2 284 ? 68.31400  49.10200  18.44600  1.000 325.73000 ? 284 GLU B O     1 
ATOM   6170 C  CB    . GLU B 2 284 ? 70.89900  47.56100  19.15500  1.000 318.51000 ? 284 GLU B CB    1 
ATOM   6171 C  CG    . GLU B 2 284 ? 71.04900  49.00100  19.71500  1.000 318.82000 ? 284 GLU B CG    1 
ATOM   6172 C  CD    . GLU B 2 284 ? 72.05000  49.13700  20.86600  1.000 323.23000 ? 284 GLU B CD    1 
ATOM   6173 O  OE1   . GLU B 2 284 ? 72.85100  48.21100  21.06700  1.000 320.88000 ? 284 GLU B OE1   1 
ATOM   6174 O  OE2   . GLU B 2 284 ? 72.05200  50.17400  21.57200  1.000 322.12000 ? 284 GLU B OE2   1 
ATOM   6175 N  N     . TYR B 2 285 ? 67.61500  46.95400  18.49000  1.000 327.19000 ? 285 TYR B N     1 
ATOM   6176 C  CA    . TYR B 2 285 ? 66.30200  47.25700  19.06400  1.000 322.92000 ? 285 TYR B CA    1 
ATOM   6177 C  C     . TYR B 2 285 ? 66.39500  47.14100  20.57400  1.000 314.65000 ? 285 TYR B C     1 
ATOM   6178 O  O     . TYR B 2 285 ? 66.82300  46.10200  21.08900  1.000 317.89000 ? 285 TYR B O     1 
ATOM   6179 C  CB    . TYR B 2 285 ? 65.18600  46.31500  18.57900  1.000 317.19000 ? 285 TYR B CB    1 
ATOM   6180 C  CG    . TYR B 2 285 ? 63.80400  46.80500  18.99400  1.000 308.45000 ? 285 TYR B CG    1 
ATOM   6181 C  CD1   . TYR B 2 285 ? 62.68900  45.96300  19.02200  1.000 303.47000 ? 285 TYR B CD1   1 
ATOM   6182 C  CD2   . TYR B 2 285 ? 63.62700  48.13600  19.33300  1.000 310.72000 ? 285 TYR B CD2   1 
ATOM   6183 C  CE1   . TYR B 2 285 ? 61.44200  46.46600  19.39500  1.000 313.02000 ? 285 TYR B CE1   1 
ATOM   6184 C  CE2   . TYR B 2 285 ? 62.41900  48.63400  19.70400  1.000 312.23000 ? 285 TYR B CE2   1 
ATOM   6185 C  CZ    . TYR B 2 285 ? 61.32500  47.81600  19.74200  1.000 315.35000 ? 285 TYR B CZ    1 
ATOM   6186 O  OH    . TYR B 2 285 ? 60.11100  48.37500  20.11200  1.000 317.61000 ? 285 TYR B OH    1 
ATOM   6187 N  N     . GLN B 2 286 ? 65.97200  48.18400  21.28200  1.000 302.02000 ? 286 GLN B N     1 
ATOM   6188 C  CA    . GLN B 2 286 ? 65.96800  48.14300  22.73600  1.000 304.97000 ? 286 GLN B CA    1 
ATOM   6189 C  C     . GLN B 2 286 ? 64.59500  47.73700  23.26000  1.000 306.25000 ? 286 GLN B C     1 
ATOM   6190 O  O     . GLN B 2 286 ? 63.61400  48.47600  23.11200  1.000 301.98000 ? 286 GLN B O     1 
ATOM   6191 C  CB    . GLN B 2 286 ? 66.38000  49.46200  23.37400  1.000 308.49000 ? 286 GLN B CB    1 
ATOM   6192 C  CG    . GLN B 2 286 ? 66.54300  49.27100  24.85700  1.000 308.37000 ? 286 GLN B CG    1 
ATOM   6193 C  CD    . GLN B 2 286 ? 66.21700  50.52300  25.60800  1.000 306.13000 ? 286 GLN B CD    1 
ATOM   6194 O  OE1   . GLN B 2 286 ? 65.93400  51.56400  25.01400  1.000 309.62000 ? 286 GLN B OE1   1 
ATOM   6195 N  NE2   . GLN B 2 286 ? 66.23500  50.43500  26.92400  1.000 300.48000 ? 286 GLN B NE2   1 
ATOM   6196 N  N     . MET B 2 287 ? 64.54200  46.54900  23.84900  1.000 319.10000 ? 287 MET B N     1 
ATOM   6197 C  CA    . MET B 2 287 ? 63.56100  46.17400  24.84500  1.000 315.59000 ? 287 MET B CA    1 
ATOM   6198 C  C     . MET B 2 287 ? 64.22200  46.37200  26.18700  1.000 318.12000 ? 287 MET B C     1 
ATOM   6199 O  O     . MET B 2 287 ? 65.44500  46.24900  26.30200  1.000 320.94000 ? 287 MET B O     1 
ATOM   6200 C  CB    . MET B 2 287 ? 63.13100  44.70200  24.69300  1.000 314.72000 ? 287 MET B CB    1 
ATOM   6201 C  CG    . MET B 2 287 ? 63.08400  44.19200  23.25200  1.000 320.42000 ? 287 MET B CG    1 
ATOM   6202 S  SD    . MET B 2 287 ? 63.21400  42.40600  22.94200  1.000 331.50000 ? 287 MET B SD    1 
ATOM   6203 C  CE    . MET B 2 287 ? 64.97000  42.05700  23.27600  1.000 317.32000 ? 287 MET B CE    1 
ATOM   6204 N  N     . SER B 2 288 ? 63.37900  46.69400  27.17100  1.000 325.09000 ? 288 SER B N     1 
ATOM   6205 C  CA    . SER B 2 288 ? 63.84400  46.89200  28.53000  1.000 335.61000 ? 288 SER B CA    1 
ATOM   6206 C  C     . SER B 2 288 ? 64.69000  45.70800  29.00000  1.000 337.44000 ? 288 SER B C     1 
ATOM   6207 O  O     . SER B 2 288 ? 65.77700  45.89800  29.55500  1.000 344.44000 ? 288 SER B O     1 
ATOM   6208 C  CB    . SER B 2 288 ? 62.64800  47.16700  29.44100  1.000 336.00000 ? 288 SER B CB    1 
ATOM   6209 O  OG    . SER B 2 288 ? 61.59400  46.30400  29.34400  1.000 336.34000 ? 288 SER B OG    1 
ATOM   6210 N  N     . LYS B 2 289 ? 64.22300  44.47300  28.76600  1.000 310.83000 ? 289 LYS B N     1 
ATOM   6211 C  CA    . LYS B 2 289 ? 64.90800  43.27500  29.29900  1.000 314.45000 ? 289 LYS B CA    1 
ATOM   6212 C  C     . LYS B 2 289 ? 66.38800  43.20400  28.87400  1.000 311.27000 ? 289 LYS B C     1 
ATOM   6213 O  O     . LYS B 2 289 ? 67.30900  43.10500  29.70300  1.000 313.29000 ? 289 LYS B O     1 
ATOM   6214 C  CB    . LYS B 2 289 ? 64.18200  42.00600  28.85800  1.000 315.69000 ? 289 LYS B CB    1 
ATOM   6215 N  N     . THR B 2 290 ? 66.63500  43.27200  27.57900  1.000 312.32000 ? 290 THR B N     1 
ATOM   6216 C  CA    . THR B 2 290 ? 67.97300  43.33000  27.00100  1.000 316.04000 ? 290 THR B CA    1 
ATOM   6217 C  C     . THR B 2 290 ? 67.80200  43.85600  25.58000  1.000 313.96000 ? 290 THR B C     1 
ATOM   6218 O  O     . THR B 2 290 ? 66.69800  44.23300  25.17700  1.000 317.62000 ? 290 THR B O     1 
ATOM   6219 C  CB    . THR B 2 290 ? 68.65900  41.95900  27.08100  1.000 311.92000 ? 290 THR B CB    1 
ATOM   6220 O  OG1   . THR B 2 290 ? 69.73000  41.84300  26.13300  1.000 301.46000 ? 290 THR B OG1   1 
ATOM   6221 C  CG2   . THR B 2 290 ? 67.65400  40.84200  26.88100  1.000 309.64000 ? 290 THR B CG2   1 
ATOM   6222 N  N     . PHE B 2 291 ? 68.89200  43.90600  24.82400  1.000 325.34000 ? 291 PHE B N     1 
ATOM   6223 C  CA    . PHE B 2 291 ? 68.74900  44.47400  23.48700  1.000 325.27000 ? 291 PHE B CA    1 
ATOM   6224 C  C     . PHE B 2 291 ? 68.47100  43.37700  22.45000  1.000 320.00000 ? 291 PHE B C     1 
ATOM   6225 O  O     . PHE B 2 291 ? 68.82600  42.20700  22.62600  1.000 313.62000 ? 291 PHE B O     1 
ATOM   6226 C  CB    . PHE B 2 291 ? 70.00600  45.26100  23.06400  1.000 327.30000 ? 291 PHE B CB    1 
ATOM   6227 C  CG    . PHE B 2 291 ? 70.27900  46.56500  23.84300  1.000 331.47000 ? 291 PHE B CG    1 
ATOM   6228 C  CD1   . PHE B 2 291 ? 69.54400  47.73500  23.64100  1.000 324.93000 ? 291 PHE B CD1   1 
ATOM   6229 C  CD2   . PHE B 2 291 ? 71.36900  46.63000  24.70700  1.000 335.73000 ? 291 PHE B CD2   1 
ATOM   6230 C  CE1   . PHE B 2 291 ? 69.86900  48.93100  24.33600  1.000 322.14000 ? 291 PHE B CE1   1 
ATOM   6231 C  CE2   . PHE B 2 291 ? 71.68500  47.81800  25.40200  1.000 330.29000 ? 291 PHE B CE2   1 
ATOM   6232 C  CZ    . PHE B 2 291 ? 70.93900  48.96400  25.22400  1.000 323.77000 ? 291 PHE B CZ    1 
ATOM   6233 N  N     . ALA B 2 292 ? 67.81300  43.77000  21.36200  1.000 320.30000 ? 292 ALA B N     1 
ATOM   6234 C  CA    . ALA B 2 292 ? 67.59000  42.91200  20.20300  1.000 318.33000 ? 292 ALA B CA    1 
ATOM   6235 C  C     . ALA B 2 292 ? 68.37500  43.47900  19.02200  1.000 319.10000 ? 292 ALA B C     1 
ATOM   6236 O  O     . ALA B 2 292 ? 68.45300  44.69700  18.85600  1.000 323.03000 ? 292 ALA B O     1 
ATOM   6237 C  CB    . ALA B 2 292 ? 66.10000  42.80100  19.86400  1.000 315.64000 ? 292 ALA B CB    1 
ATOM   6238 N  N     . TYR B 2 293 ? 68.97100  42.61100  18.20800  1.000 315.25000 ? 293 TYR B N     1 
ATOM   6239 C  CA    . TYR B 2 293 ? 69.86200  43.03000  17.12000  1.000 310.12000 ? 293 TYR B CA    1 
ATOM   6240 C  C     . TYR B 2 293 ? 69.30300  42.65400  15.75100  1.000 304.83000 ? 293 TYR B C     1 
ATOM   6241 O  O     . TYR B 2 293 ? 69.23600  41.47700  15.39000  1.000 299.19000 ? 293 TYR B O     1 
ATOM   6242 C  CB    . TYR B 2 293 ? 71.25600  42.44200  17.31600  1.000 310.58000 ? 293 TYR B CB    1 
ATOM   6243 C  CG    . TYR B 2 293 ? 71.80100  42.84400  18.65200  1.000 311.97000 ? 293 TYR B CG    1 
ATOM   6244 C  CD1   . TYR B 2 293 ? 71.92000  44.18400  18.99000  1.000 319.22000 ? 293 TYR B CD1   1 
ATOM   6245 C  CD2   . TYR B 2 293 ? 72.14900  41.89300  19.59500  1.000 316.28000 ? 293 TYR B CD2   1 
ATOM   6246 C  CE1   . TYR B 2 293 ? 72.39200  44.56400  20.22600  1.000 328.66000 ? 293 TYR B CE1   1 
ATOM   6247 C  CE2   . TYR B 2 293 ? 72.61700  42.26100  20.83400  1.000 322.70000 ? 293 TYR B CE2   1 
ATOM   6248 C  CZ    . TYR B 2 293 ? 72.74800  43.59400  21.15100  1.000 328.46000 ? 293 TYR B CZ    1 
ATOM   6249 O  OH    . TYR B 2 293 ? 73.23100  43.93200  22.40500  1.000 332.83000 ? 293 TYR B OH    1 
ATOM   6250 N  N     . TRP B 2 294 ? 68.90000  43.67100  15.00900  1.000 305.76000 ? 294 TRP B N     1 
ATOM   6251 C  CA    . TRP B 2 294 ? 68.28400  43.55200  13.70200  1.000 306.40000 ? 294 TRP B CA    1 
ATOM   6252 C  C     . TRP B 2 294 ? 69.16600  44.28300  12.71600  1.000 308.20000 ? 294 TRP B C     1 
ATOM   6253 O  O     . TRP B 2 294 ? 69.59000  45.41300  12.97600  1.000 311.35000 ? 294 TRP B O     1 
ATOM   6254 C  CB    . TRP B 2 294 ? 66.87700  44.15600  13.70500  1.000 310.26000 ? 294 TRP B CB    1 
ATOM   6255 C  CG    . TRP B 2 294 ? 66.83400  45.66200  13.94700  1.000 317.24000 ? 294 TRP B CG    1 
ATOM   6256 C  CD1   . TRP B 2 294 ? 67.02800  46.27500  15.14900  1.000 319.12000 ? 294 TRP B CD1   1 
ATOM   6257 C  CD2   . TRP B 2 294 ? 66.59300  46.72900  13.00800  1.000 313.80000 ? 294 TRP B CD2   1 
ATOM   6258 N  NE1   . TRP B 2 294 ? 66.94200  47.62700  15.04600  1.000 316.32000 ? 294 TRP B NE1   1 
ATOM   6259 C  CE2   . TRP B 2 294 ? 66.66600  47.94000  13.73900  1.000 312.81000 ? 294 TRP B CE2   1 
ATOM   6260 C  CE3   . TRP B 2 294 ? 66.34600  46.78600  11.62900  1.000 311.66000 ? 294 TRP B CE3   1 
ATOM   6261 C  CZ2   . TRP B 2 294 ? 66.49100  49.16900  13.12900  1.000 309.92000 ? 294 TRP B CZ2   1 
ATOM   6262 C  CZ3   . TRP B 2 294 ? 66.15400  47.98500  11.04200  1.000 314.68000 ? 294 TRP B CZ3   1 
ATOM   6263 C  CH2   . TRP B 2 294 ? 66.22000  49.18100  11.77300  1.000 314.78000 ? 294 TRP B CH2   1 
ATOM   6264 N  N     . ILE B 2 295 ? 69.50400  43.62000  11.62400  1.000 302.29000 ? 295 ILE B N     1 
ATOM   6265 C  CA    . ILE B 2 295 ? 70.28500  44.31000  10.61800  1.000 299.64000 ? 295 ILE B CA    1 
ATOM   6266 C  C     . ILE B 2 295 ? 69.37900  45.30100  9.88800   1.000 301.29000 ? 295 ILE B C     1 
ATOM   6267 O  O     . ILE B 2 295 ? 68.18800  45.01900  9.65300   1.000 301.27000 ? 295 ILE B O     1 
ATOM   6268 C  CB    . ILE B 2 295 ? 70.96700  43.26300  9.71900   1.000 298.99000 ? 295 ILE B CB    1 
ATOM   6269 C  CG1   . ILE B 2 295 ? 71.28600  42.04500  10.59100  1.000 292.94000 ? 295 ILE B CG1   1 
ATOM   6270 C  CG2   . ILE B 2 295 ? 72.28400  43.81300  9.16200   1.000 307.48000 ? 295 ILE B CG2   1 
ATOM   6271 C  CD1   . ILE B 2 295 ? 71.77100  40.76800  9.92900   1.000 295.27000 ? 295 ILE B CD1   1 
ATOM   6272 N  N     . GLU B 2 296 ? 69.92900  46.50400  9.60300   1.000 287.88000 ? 296 GLU B N     1 
ATOM   6273 C  CA    . GLU B 2 296 ? 69.26900  47.60400  8.91200   1.000 293.34000 ? 296 GLU B CA    1 
ATOM   6274 C  C     . GLU B 2 296 ? 69.08700  47.27500  7.42200   1.000 301.16000 ? 296 GLU B C     1 
ATOM   6275 O  O     . GLU B 2 296 ? 69.67300  46.32100  6.89600   1.000 309.73000 ? 296 GLU B O     1 
ATOM   6276 C  CB    . GLU B 2 296 ? 70.08100  48.87700  9.09900   1.000 294.53000 ? 296 GLU B CB    1 
ATOM   6277 C  CG    . GLU B 2 296 ? 71.36400  48.77600  9.90800   1.000 306.03000 ? 296 GLU B CG    1 
ATOM   6278 C  CD    . GLU B 2 296 ? 72.21400  50.04400  9.78800   1.000 310.09000 ? 296 GLU B CD    1 
ATOM   6279 O  OE1   . GLU B 2 296 ? 71.84000  50.93500  9.02200   1.000 300.88000 ? 296 GLU B OE1   1 
ATOM   6280 O  OE2   . GLU B 2 296 ? 73.25900  50.16000  10.44300  1.000 313.22000 ? 296 GLU B OE2   1 
ATOM   6281 N  N     . LYS B 2 297 ? 68.25900  48.07300  6.73600   1.000 294.14000 ? 297 LYS B N     1 
ATOM   6282 C  CA    . LYS B 2 297 ? 67.98000  47.82500  5.32300   1.000 289.93000 ? 297 LYS B CA    1 
ATOM   6283 C  C     . LYS B 2 297 ? 69.21400  48.08600  4.46800   1.000 286.13000 ? 297 LYS B C     1 
ATOM   6284 O  O     . LYS B 2 297 ? 69.91400  49.08600  4.65200   1.000 284.93000 ? 297 LYS B O     1 
ATOM   6285 C  CB    . LYS B 2 297 ? 66.82500  48.70000  4.85400   1.000 289.44000 ? 297 LYS B CB    1 
ATOM   6286 C  CG    . LYS B 2 297 ? 66.59400  48.70900  3.35900   1.000 286.23000 ? 297 LYS B CG    1 
ATOM   6287 C  CD    . LYS B 2 297 ? 65.24000  48.13700  3.00100   1.000 285.30000 ? 297 LYS B CD    1 
ATOM   6288 C  CE    . LYS B 2 297 ? 64.81800  48.67500  1.65900   1.000 287.46000 ? 297 LYS B CE    1 
ATOM   6289 N  NZ    . LYS B 2 297 ? 65.02400  50.14100  1.69300   1.000 285.10000 ? 297 LYS B NZ    1 
ATOM   6290 N  N     . GLY B 2 298 ? 69.49000  47.16100  3.54000   1.000 277.78000 ? 298 GLY B N     1 
ATOM   6291 C  CA    . GLY B 2 298 ? 70.54200  47.34600  2.56300   1.000 283.44000 ? 298 GLY B CA    1 
ATOM   6292 C  C     . GLY B 2 298 ? 71.92800  46.91600  2.98300   1.000 281.49000 ? 298 GLY B C     1 
ATOM   6293 O  O     . GLY B 2 298 ? 72.86700  47.04300  2.17500   1.000 283.28000 ? 298 GLY B O     1 
ATOM   6294 N  N     . LYS B 2 299 ? 72.10300  46.43100  4.21200   1.000 282.30000 ? 299 LYS B N     1 
ATOM   6295 C  CA    . LYS B 2 299 ? 73.44100  46.05300  4.64100   1.000 283.01000 ? 299 LYS B CA    1 
ATOM   6296 C  C     . LYS B 2 299 ? 73.89500  44.77200  3.95200   1.000 277.24000 ? 299 LYS B C     1 
ATOM   6297 O  O     . LYS B 2 299 ? 75.07700  44.62100  3.63300   1.000 281.36000 ? 299 LYS B O     1 
ATOM   6298 C  CB    . LYS B 2 299 ? 73.47700  45.89400  6.16200   1.000 296.98000 ? 299 LYS B CB    1 
ATOM   6299 C  CG    . LYS B 2 299 ? 74.67800  46.56700  6.82700   1.000 299.16000 ? 299 LYS B CG    1 
ATOM   6300 C  CD    . LYS B 2 299 ? 74.53300  48.08300  6.84400   1.000 296.74000 ? 299 LYS B CD    1 
ATOM   6301 C  CE    . LYS B 2 299 ? 75.83200  48.74700  7.24800   1.000 291.31000 ? 299 LYS B CE    1 
ATOM   6302 N  NZ    . LYS B 2 299 ? 75.93300  50.06100  6.58500   1.000 295.60000 ? 299 LYS B NZ    1 
ATOM   6303 N  N     . LEU B 2 300 ? 72.97300  43.84200  3.70800   1.000 278.42000 ? 300 LEU B N     1 
ATOM   6304 C  CA    . LEU B 2 300 ? 73.23700  42.65000  2.91200   1.000 283.04000 ? 300 LEU B CA    1 
ATOM   6305 C  C     . LEU B 2 300 ? 72.59300  42.77300  1.54700   1.000 288.42000 ? 300 LEU B C     1 
ATOM   6306 O  O     . LEU B 2 300 ? 71.51400  43.35500  1.40600   1.000 288.80000 ? 300 LEU B O     1 
ATOM   6307 C  CB    . LEU B 2 300 ? 72.68600  41.38000  3.54500   1.000 284.50000 ? 300 LEU B CB    1 
ATOM   6308 C  CG    . LEU B 2 300 ? 73.12900  41.14000  4.95600   1.000 275.91000 ? 300 LEU B CG    1 
ATOM   6309 C  CD1   . LEU B 2 300 ? 71.90000  40.74400  5.73100   1.000 287.09000 ? 300 LEU B CD1   1 
ATOM   6310 C  CD2   . LEU B 2 300 ? 74.17600  40.06900  4.97700   1.000 269.17000 ? 300 LEU B CD2   1 
ATOM   6311 N  N     . GLU B 2 301 ? 73.23700  42.15900  0.55800   1.000 297.59000 ? 301 GLU B N     1 
ATOM   6312 C  CA    . GLU B 2 301 ? 72.86000  42.40700  -0.82500  1.000 296.84000 ? 301 GLU B CA    1 
ATOM   6313 C  C     . GLU B 2 301 ? 71.41100  42.01000  -1.06000  1.000 286.45000 ? 301 GLU B C     1 
ATOM   6314 O  O     . GLU B 2 301 ? 71.01000  40.86500  -0.80300  1.000 275.54000 ? 301 GLU B O     1 
ATOM   6315 C  CB    . GLU B 2 301 ? 73.77800  41.66700  -1.78200  1.000 291.13000 ? 301 GLU B CB    1 
ATOM   6316 C  CG    . GLU B 2 301 ? 73.67800  42.19400  -3.19500  1.000 297.26000 ? 301 GLU B CG    1 
ATOM   6317 C  CD    . GLU B 2 301 ? 74.12700  41.18700  -4.21500  1.000 298.17000 ? 301 GLU B CD    1 
ATOM   6318 O  OE1   . GLU B 2 301 ? 75.11800  40.48000  -3.97200  1.000 309.64000 ? 301 GLU B OE1   1 
ATOM   6319 O  OE2   . GLU B 2 301 ? 73.46600  41.07400  -5.25700  1.000 289.33000 ? 301 GLU B OE2   1 
ATOM   6320 N  N     . LYS B 2 302 ? 70.63700  42.98100  -1.55500  1.000 295.16000 ? 302 LYS B N     1 
ATOM   6321 C  CA    . LYS B 2 302 ? 69.20300  42.83400  -1.75500  1.000 290.09000 ? 302 LYS B CA    1 
ATOM   6322 C  C     . LYS B 2 302 ? 68.51000  42.35400  -0.48900  1.000 297.71000 ? 302 LYS B C     1 
ATOM   6323 O  O     . LYS B 2 302 ? 67.49400  41.66600  -0.53900  1.000 293.95000 ? 302 LYS B O     1 
ATOM   6324 C  CB    . LYS B 2 302 ? 68.89200  41.89900  -2.92100  1.000 293.32000 ? 302 LYS B CB    1 
ATOM   6325 C  CG    . LYS B 2 302 ? 68.13200  42.59300  -4.04800  1.000 299.43000 ? 302 LYS B CG    1 
ATOM   6326 C  CD    . LYS B 2 302 ? 69.02100  42.95900  -5.22900  1.000 292.79000 ? 302 LYS B CD    1 
ATOM   6327 C  CE    . LYS B 2 302 ? 68.97400  44.45200  -5.52500  1.000 290.71000 ? 302 LYS B CE    1 
ATOM   6328 N  NZ    . LYS B 2 302 ? 69.13300  44.75200  -6.98500  1.000 275.89000 ? 302 LYS B NZ    1 
ATOM   6329 N  N     . ASP B 2 303 ? 69.06200  42.70900  0.66000   1.000 302.36000 ? 303 ASP B N     1 
ATOM   6330 C  CA    . ASP B 2 303 ? 68.47900  42.34500  1.95300   1.000 283.91000 ? 303 ASP B CA    1 
ATOM   6331 C  C     . ASP B 2 303 ? 68.39000  40.83300  2.10500   1.000 282.32000 ? 303 ASP B C     1 
ATOM   6332 O  O     . ASP B 2 303 ? 67.39100  40.28200  2.58700   1.000 278.03000 ? 303 ASP B O     1 
ATOM   6333 C  CB    . ASP B 2 303 ? 67.11000  43.00100  2.15300   1.000 283.29000 ? 303 ASP B CB    1 
ATOM   6334 C  CG    . ASP B 2 303 ? 67.19900  44.50400  2.20900   1.000 287.05000 ? 303 ASP B CG    1 
ATOM   6335 O  OD1   . ASP B 2 303 ? 68.21200  45.05200  2.69700   1.000 292.89000 ? 303 ASP B OD1   1 
ATOM   6336 O  OD2   . ASP B 2 303 ? 66.22500  45.14600  1.75900   1.000 285.23000 ? 303 ASP B OD2   1 
ATOM   6337 N  N     . LYS B 2 304 ? 69.46000  40.16800  1.70500   1.000 282.03000 ? 304 LYS B N     1 
ATOM   6338 C  CA    . LYS B 2 304 ? 69.59600  38.75100  1.90700   1.000 273.64000 ? 304 LYS B CA    1 
ATOM   6339 C  C     . LYS B 2 304 ? 71.00200  38.42900  2.35000   1.000 273.90000 ? 304 LYS B C     1 
ATOM   6340 O  O     . LYS B 2 304 ? 71.96300  39.02500  1.88000   1.000 278.85000 ? 304 LYS B O     1 
ATOM   6341 C  CB    . LYS B 2 304 ? 69.28500  38.00800  0.65700   1.000 275.68000 ? 304 LYS B CB    1 
ATOM   6342 C  CG    . LYS B 2 304 ? 67.85700  37.88900  0.47400   1.000 279.28000 ? 304 LYS B CG    1 
ATOM   6343 C  CD    . LYS B 2 304 ? 67.67600  37.04800  -0.67300  1.000 281.03000 ? 304 LYS B CD    1 
ATOM   6344 C  CE    . LYS B 2 304 ? 66.33200  36.45200  -0.62100  1.000 280.12000 ? 304 LYS B CE    1 
ATOM   6345 N  NZ    . LYS B 2 304 ? 66.49300  34.98500  -0.58600  1.000 284.28000 ? 304 LYS B NZ    1 
ATOM   6346 N  N     . PHE B 2 305 ? 71.10300  37.48400  3.27300   1.000 288.57000 ? 305 PHE B N     1 
ATOM   6347 C  CA    . PHE B 2 305 ? 72.36300  36.90500  3.72000   1.000 292.55000 ? 305 PHE B CA    1 
ATOM   6348 C  C     . PHE B 2 305 ? 72.36200  35.43600  3.30500   1.000 303.79000 ? 305 PHE B C     1 
ATOM   6349 O  O     . PHE B 2 305 ? 71.34700  34.75100  3.49800   1.000 308.88000 ? 305 PHE B O     1 
ATOM   6350 C  CB    . PHE B 2 305 ? 72.51300  37.05300  5.25000   1.000 290.81000 ? 305 PHE B CB    1 
ATOM   6351 C  CG    . PHE B 2 305 ? 73.73000  36.36500  5.81000   1.000 287.54000 ? 305 PHE B CG    1 
ATOM   6352 C  CD1   . PHE B 2 305 ? 73.62200  35.18800  6.53800   1.000 287.57000 ? 305 PHE B CD1   1 
ATOM   6353 C  CD2   . PHE B 2 305 ? 74.98400  36.89100  5.58200   1.000 286.87000 ? 305 PHE B CD2   1 
ATOM   6354 C  CE1   . PHE B 2 305 ? 74.74200  34.56000  7.01300   1.000 287.02000 ? 305 PHE B CE1   1 
ATOM   6355 C  CE2   . PHE B 2 305 ? 76.09900  36.27800  6.05400   1.000 292.01000 ? 305 PHE B CE2   1 
ATOM   6356 C  CZ    . PHE B 2 305 ? 75.98700  35.10500  6.76400   1.000 291.83000 ? 305 PHE B CZ    1 
ATOM   6357 N  N     . GLU B 2 306 ? 73.46300  34.96700  2.67700   1.000 297.84000 ? 306 GLU B N     1 
ATOM   6358 C  CA    . GLU B 2 306 ? 73.72000  33.51900  2.48700   1.000 301.85000 ? 306 GLU B CA    1 
ATOM   6359 C  C     . GLU B 2 306 ? 72.46200  32.78100  1.93300   1.000 302.31000 ? 306 GLU B C     1 
ATOM   6360 O  O     . GLU B 2 306 ? 72.20500  31.62500  2.26000   1.000 314.56000 ? 306 GLU B O     1 
ATOM   6361 C  CB    . GLU B 2 306 ? 74.27000  32.91600  3.82400   1.000 296.80000 ? 306 GLU B CB    1 
ATOM   6362 C  CG    . GLU B 2 306 ? 75.18200  31.61200  3.77000   1.000 293.26000 ? 306 GLU B CG    1 
ATOM   6363 C  CD    . GLU B 2 306 ? 76.16000  31.41000  4.96800   1.000 287.98000 ? 306 GLU B CD    1 
ATOM   6364 O  OE1   . GLU B 2 306 ? 76.46100  32.37900  5.68500   1.000 286.81000 ? 306 GLU B OE1   1 
ATOM   6365 O  OE2   . GLU B 2 306 ? 76.66800  30.28700  5.17300   1.000 285.28000 ? 306 GLU B OE2   1 
ATOM   6366 N  N     . LYS B 2 307 ? 71.66000  33.46900  1.09200   1.000 280.96000 ? 307 LYS B N     1 
ATOM   6367 C  CA    . LYS B 2 307 ? 70.40800  33.07800  0.43000   1.000 277.42000 ? 307 LYS B CA    1 
ATOM   6368 C  C     . LYS B 2 307 ? 69.19400  33.31800  1.31000   1.000 275.29000 ? 307 LYS B C     1 
ATOM   6369 O  O     . LYS B 2 307 ? 68.06600  33.17600  0.84400   1.000 279.91000 ? 307 LYS B O     1 
ATOM   6370 C  CB    . LYS B 2 307 ? 70.40300  31.61800  -0.04700  1.000 283.40000 ? 307 LYS B CB    1 
ATOM   6371 C  CG    . LYS B 2 307 ? 69.69900  30.62000  0.90200   1.000 293.69000 ? 307 LYS B CG    1 
ATOM   6372 C  CD    . LYS B 2 307 ? 69.87300  29.16700  0.42100   1.000 307.17000 ? 307 LYS B CD    1 
ATOM   6373 C  CE    . LYS B 2 307 ? 70.86000  29.06000  -0.73100  1.000 311.01000 ? 307 LYS B CE    1 
ATOM   6374 N  NZ    . LYS B 2 307 ? 70.29100  28.11900  -1.73400  1.000 321.86000 ? 307 LYS B NZ    1 
ATOM   6375 N  N     . ILE B 2 308 ? 69.37900  33.61900  2.51200   1.000 295.18000 ? 308 ILE B N     1 
ATOM   6376 C  CA    . ILE B 2 308 ? 68.25400  33.83900  3.40300   1.000 301.74000 ? 308 ILE B CA    1 
ATOM   6377 C  C     . ILE B 2 308 ? 67.84100  35.29000  3.25900   1.000 294.86000 ? 308 ILE B C     1 
ATOM   6378 O  O     . ILE B 2 308 ? 68.61200  36.12700  2.78900   1.000 291.57000 ? 308 ILE B O     1 
ATOM   6379 C  CB    . ILE B 2 308 ? 68.62900  33.47400  4.85800   1.000 313.71000 ? 308 ILE B CB    1 
ATOM   6380 C  CG1   . ILE B 2 308 ? 69.26000  32.07300  4.88900   1.000 320.51000 ? 308 ILE B CG1   1 
ATOM   6381 C  CG2   . ILE B 2 308 ? 67.41100  33.60900  5.80700   1.000 295.02000 ? 308 ILE B CG2   1 
ATOM   6382 C  CD1   . ILE B 2 308 ? 68.39600  30.95500  4.27400   1.000 315.38000 ? 308 ILE B CD1   1 
ATOM   6383 N  N     . LYS B 2 309 ? 66.61300  35.58600  3.65000   1.000 291.80000 ? 309 LYS B N     1 
ATOM   6384 C  CA    . LYS B 2 309 ? 66.08800  36.93700  3.62500   1.000 288.17000 ? 309 LYS B CA    1 
ATOM   6385 C  C     . LYS B 2 309 ? 65.84900  37.38600  5.06300   1.000 283.73000 ? 309 LYS B C     1 
ATOM   6386 O  O     . LYS B 2 309 ? 64.85100  37.02700  5.69100   1.000 277.84000 ? 309 LYS B O     1 
ATOM   6387 C  CB    . LYS B 2 309 ? 64.84200  36.98100  2.82000   1.000 281.24000 ? 309 LYS B CB    1 
ATOM   6388 C  CG    . LYS B 2 309 ? 64.30200  38.31700  2.78800   1.000 283.18000 ? 309 LYS B CG    1 
ATOM   6389 C  CD    . LYS B 2 309 ? 63.09000  38.33400  1.98200   1.000 281.72000 ? 309 LYS B CD    1 
ATOM   6390 C  CE    . LYS B 2 309 ? 62.97600  39.72200  1.48700   1.000 291.61000 ? 309 LYS B CE    1 
ATOM   6391 N  NZ    . LYS B 2 309 ? 61.63100  40.24900  1.75100   1.000 295.89000 ? 309 LYS B NZ    1 
ATOM   6392 N  N     . LEU B 2 310 ? 66.79100  38.15400  5.58900   1.000 288.96000 ? 310 LEU B N     1 
ATOM   6393 C  CA    . LEU B 2 310 ? 66.73400  38.59400  6.97500   1.000 288.65000 ? 310 LEU B CA    1 
ATOM   6394 C  C     . LEU B 2 310 ? 66.16500  39.99600  7.12400   1.000 285.28000 ? 310 LEU B C     1 
ATOM   6395 O  O     . LEU B 2 310 ? 66.01800  40.48300  8.24800   1.000 283.90000 ? 310 LEU B O     1 
ATOM   6396 C  CB    . LEU B 2 310 ? 68.13200  38.52600  7.61400   1.000 294.36000 ? 310 LEU B CB    1 
ATOM   6397 C  CG    . LEU B 2 310 ? 68.81600  37.15200  7.81800   1.000 292.40000 ? 310 LEU B CG    1 
ATOM   6398 C  CD1   . LEU B 2 310 ? 70.10100  37.21300  8.67200   1.000 294.18000 ? 310 LEU B CD1   1 
ATOM   6399 C  CD2   . LEU B 2 310 ? 67.85500  36.16000  8.42500   1.000 285.73000 ? 310 LEU B CD2   1 
ATOM   6400 N  N     . VAL B 2 311 ? 65.86200  40.66600  6.02500   1.000 277.53000 ? 311 VAL B N     1 
ATOM   6401 C  CA    . VAL B 2 311 ? 65.09600  41.90200  6.07100   1.000 277.02000 ? 311 VAL B CA    1 
ATOM   6402 C  C     . VAL B 2 311 ? 64.09700  41.83700  4.93900   1.000 277.88000 ? 311 VAL B C     1 
ATOM   6403 O  O     . VAL B 2 311 ? 64.44700  41.45500  3.81700   1.000 280.79000 ? 311 VAL B O     1 
ATOM   6404 C  CB    . VAL B 2 311 ? 66.00000  43.14400  5.95100   1.000 281.14000 ? 311 VAL B CB    1 
ATOM   6405 C  CG1   . VAL B 2 311 ? 65.21000  44.33300  5.41100   1.000 284.93000 ? 311 VAL B CG1   1 
ATOM   6406 C  CG2   . VAL B 2 311 ? 66.61200  43.45100  7.29100   1.000 287.85000 ? 311 VAL B CG2   1 
ATOM   6407 N  N     . GLY B 2 312 ? 62.85700  42.17700  5.23200   1.000 281.97000 ? 312 GLY B N     1 
ATOM   6408 C  CA    . GLY B 2 312 ? 61.84300  42.09700  4.21500   1.000 283.15000 ? 312 GLY B CA    1 
ATOM   6409 C  C     . GLY B 2 312 ? 60.84100  43.20900  4.32300   1.000 285.23000 ? 312 GLY B C     1 
ATOM   6410 O  O     . GLY B 2 312 ? 61.13000  44.29800  4.81400   1.000 288.31000 ? 312 GLY B O     1 
ATOM   6411 N  N     . LYS B 2 313 ? 59.62500  42.93300  3.88600   1.000 276.90000 ? 313 LYS B N     1 
ATOM   6412 C  CA    . LYS B 2 313 ? 58.65300  44.00400  3.87500   1.000 279.65000 ? 313 LYS B CA    1 
ATOM   6413 C  C     . LYS B 2 313 ? 57.28000  43.48700  4.20100   1.000 281.17000 ? 313 LYS B C     1 
ATOM   6414 O  O     . LYS B 2 313 ? 56.88000  42.41100  3.75800   1.000 280.27000 ? 313 LYS B O     1 
ATOM   6415 C  CB    . LYS B 2 313 ? 58.59900  44.70700  2.53400   1.000 280.87000 ? 313 LYS B CB    1 
ATOM   6416 C  CG    . LYS B 2 313 ? 57.84600  46.04500  2.58800   1.000 294.95000 ? 313 LYS B CG    1 
ATOM   6417 C  CD    . LYS B 2 313 ? 58.48300  47.06000  1.62200   1.000 317.10000 ? 313 LYS B CD    1 
ATOM   6418 C  CE    . LYS B 2 313 ? 57.98900  48.51100  1.80200   1.000 318.96000 ? 313 LYS B CE    1 
ATOM   6419 N  NZ    . LYS B 2 313 ? 58.78500  49.50900  0.97300   1.000 313.53000 ? 313 LYS B NZ    1 
ATOM   6420 N  N     . GLN B 2 314 ? 56.56200  44.30300  4.94800   1.000 288.82000 ? 314 GLN B N     1 
ATOM   6421 C  CA    . GLN B 2 314 ? 55.18800  44.04300  5.31100   1.000 290.86000 ? 314 GLN B CA    1 
ATOM   6422 C  C     . GLN B 2 314 ? 54.41400  45.33700  5.17500   1.000 291.97000 ? 314 GLN B C     1 
ATOM   6423 O  O     . GLN B 2 314 ? 54.75200  46.32700  5.83600   1.000 292.30000 ? 314 GLN B O     1 
ATOM   6424 C  CB    . GLN B 2 314 ? 55.10400  43.54200  6.74900   1.000 305.23000 ? 314 GLN B CB    1 
ATOM   6425 C  CG    . GLN B 2 314 ? 53.66600  43.58300  7.27400   1.000 310.30000 ? 314 GLN B CG    1 
ATOM   6426 C  CD    . GLN B 2 314 ? 53.53000  43.72600  8.77200   1.000 297.52000 ? 314 GLN B CD    1 
ATOM   6427 O  OE1   . GLN B 2 314 ? 54.29700  43.16000  9.55100   1.000 298.20000 ? 314 GLN B OE1   1 
ATOM   6428 N  NE2   . GLN B 2 314 ? 52.52700  44.49100  9.18500   1.000 293.57000 ? 314 GLN B NE2   1 
ATOM   6429 N  N     . LYS B 2 315 ? 53.37400  45.33200  4.34600   1.000 289.87000 ? 315 LYS B N     1 
ATOM   6430 C  CA    . LYS B 2 315 ? 52.48800  46.50300  4.26500   1.000 290.48000 ? 315 LYS B CA    1 
ATOM   6431 C  C     . LYS B 2 315 ? 53.40900  47.71500  3.98100   1.000 292.69000 ? 315 LYS B C     1 
ATOM   6432 O  O     . LYS B 2 315 ? 54.27500  47.62500  3.14300   1.000 295.74000 ? 315 LYS B O     1 
ATOM   6433 C  CB    . LYS B 2 315 ? 51.66500  46.59500  5.51300   1.000 297.10000 ? 315 LYS B CB    1 
ATOM   6434 C  CG    . LYS B 2 315 ? 50.38600  47.34100  5.33900   1.000 303.48000 ? 315 LYS B CG    1 
ATOM   6435 C  CD    . LYS B 2 315 ? 49.96000  47.91400  6.66100   1.000 308.02000 ? 315 LYS B CD    1 
ATOM   6436 C  CE    . LYS B 2 315 ? 48.49800  47.63600  6.96100   1.000 311.63000 ? 315 LYS B CE    1 
ATOM   6437 N  NZ    . LYS B 2 315 ? 47.89000  48.68400  7.83000   1.000 302.38000 ? 315 LYS B NZ    1 
ATOM   6438 N  N     . ASN B 2 316 ? 53.25300  48.80600  4.71700   1.000 291.35000 ? 316 ASN B N     1 
ATOM   6439 C  CA    . ASN B 2 316 ? 54.16800  49.91800  4.49300   1.000 289.97000 ? 316 ASN B CA    1 
ATOM   6440 C  C     . ASN B 2 316 ? 55.33500  49.90200  5.44700   1.000 289.82000 ? 316 ASN B C     1 
ATOM   6441 O  O     . ASN B 2 316 ? 56.01000  50.92200  5.60900   1.000 294.65000 ? 316 ASN B O     1 
ATOM   6442 C  CB    . ASN B 2 316 ? 53.43100  51.24000  4.61300   1.000 287.05000 ? 316 ASN B CB    1 
ATOM   6443 C  CG    . ASN B 2 316 ? 52.21700  51.13300  5.45900   1.000 291.98000 ? 316 ASN B CG    1 
ATOM   6444 O  OD1   . ASN B 2 316 ? 52.22400  51.49300  6.63400   1.000 298.64000 ? 316 ASN B OD1   1 
ATOM   6445 N  ND2   . ASN B 2 316 ? 51.14800  50.64000  4.86700   1.000 287.99000 ? 316 ASN B ND2   1 
ATOM   6446 N  N     . LYS B 2 317 ? 55.60300  48.77400  6.07100   1.000 281.86000 ? 317 LYS B N     1 
ATOM   6447 C  CA    . LYS B 2 317 ? 56.65500  48.69800  7.06100   1.000 283.06000 ? 317 LYS B CA    1 
ATOM   6448 C  C     . LYS B 2 317 ? 57.59500  47.56800  6.70700   1.000 282.76000 ? 317 LYS B C     1 
ATOM   6449 O  O     . LYS B 2 317 ? 57.16400  46.44400  6.44900   1.000 283.89000 ? 317 LYS B O     1 
ATOM   6450 C  CB    . LYS B 2 317 ? 56.05800  48.51100  8.43800   1.000 279.03000 ? 317 LYS B CB    1 
ATOM   6451 C  CG    . LYS B 2 317 ? 54.70800  49.16000  8.54700   1.000 279.30000 ? 317 LYS B CG    1 
ATOM   6452 C  CD    . LYS B 2 317 ? 53.79500  48.33000  9.39300   1.000 281.86000 ? 317 LYS B CD    1 
ATOM   6453 C  CE    . LYS B 2 317 ? 52.37500  48.83100  9.31100   1.000 285.25000 ? 317 LYS B CE    1 
ATOM   6454 N  NZ    . LYS B 2 317 ? 52.29200  50.25600  9.72800   1.000 291.99000 ? 317 LYS B NZ    1 
ATOM   6455 N  N     . TYR B 2 318 ? 58.87100  47.88100  6.64700   1.000 296.37000 ? 318 TYR B N     1 
ATOM   6456 C  CA    . TYR B 2 318 ? 59.84500  46.82700  6.46200   1.000 296.82000 ? 318 TYR B CA    1 
ATOM   6457 C  C     . TYR B 2 318 ? 59.93300  46.00200  7.73100   1.000 294.73000 ? 318 TYR B C     1 
ATOM   6458 O  O     . TYR B 2 318 ? 59.83700  46.53500  8.84200   1.000 297.64000 ? 318 TYR B O     1 
ATOM   6459 C  CB    . TYR B 2 318 ? 61.22000  47.40800  6.16200   1.000 310.83000 ? 318 TYR B CB    1 
ATOM   6460 C  CG    . TYR B 2 318 ? 61.31500  48.33700  4.98900   1.000 314.96000 ? 318 TYR B CG    1 
ATOM   6461 C  CD1   . TYR B 2 318 ? 61.62400  47.85100  3.73100   1.000 314.78000 ? 318 TYR B CD1   1 
ATOM   6462 C  CD2   . TYR B 2 318 ? 61.16000  49.71100  5.15000   1.000 314.73000 ? 318 TYR B CD2   1 
ATOM   6463 C  CE1   . TYR B 2 318 ? 61.73400  48.69800  2.65800   1.000 312.05000 ? 318 TYR B CE1   1 
ATOM   6464 C  CE2   . TYR B 2 318 ? 61.27600  50.56500  4.07200   1.000 311.92000 ? 318 TYR B CE2   1 
ATOM   6465 C  CZ    . TYR B 2 318 ? 61.55900  50.05000  2.82700   1.000 309.88000 ? 318 TYR B CZ    1 
ATOM   6466 O  OH    . TYR B 2 318 ? 61.68400  50.89000  1.74400   1.000 308.88000 ? 318 TYR B OH    1 
ATOM   6467 N  N     . TRP B 2 319 ? 60.16200  44.70800  7.57800   1.000 296.06000 ? 319 TRP B N     1 
ATOM   6468 C  CA    . TRP B 2 319 ? 60.51400  43.90700  8.73600   1.000 298.74000 ? 319 TRP B CA    1 
ATOM   6469 C  C     . TRP B 2 319 ? 61.99700  43.53900  8.69500   1.000 291.96000 ? 319 TRP B C     1 
ATOM   6470 O  O     . TRP B 2 319 ? 62.58200  43.42700  7.61500   1.000 290.29000 ? 319 TRP B O     1 
ATOM   6471 C  CB    . TRP B 2 319 ? 59.62300  42.66600  8.79500   1.000 301.67000 ? 319 TRP B CB    1 
ATOM   6472 C  CG    . TRP B 2 319 ? 59.80200  41.70100  7.67800   1.000 287.24000 ? 319 TRP B CG    1 
ATOM   6473 C  CD1   . TRP B 2 319 ? 58.98200  41.53100  6.60500   1.000 286.84000 ? 319 TRP B CD1   1 
ATOM   6474 C  CD2   . TRP B 2 319 ? 60.85800  40.73800  7.53700   1.000 285.39000 ? 319 TRP B CD2   1 
ATOM   6475 N  NE1   . TRP B 2 319 ? 59.46500  40.53200  5.80700   1.000 281.77000 ? 319 TRP B NE1   1 
ATOM   6476 C  CE2   . TRP B 2 319 ? 60.61300  40.02600  6.36200   1.000 281.86000 ? 319 TRP B CE2   1 
ATOM   6477 C  CE3   . TRP B 2 319 ? 61.98900  40.41100  8.29600   1.000 289.35000 ? 319 TRP B CE3   1 
ATOM   6478 C  CZ2   . TRP B 2 319 ? 61.46600  39.01400  5.91400   1.000 283.71000 ? 319 TRP B CZ2   1 
ATOM   6479 C  CZ3   . TRP B 2 319 ? 62.83500  39.40200  7.84500   1.000 287.51000 ? 319 TRP B CZ3   1 
ATOM   6480 C  CH2   . TRP B 2 319 ? 62.56600  38.71900  6.67300   1.000 283.80000 ? 319 TRP B CH2   1 
ATOM   6481 N  N     . HIS B 2 320 ? 62.61600  43.38900  9.88100   1.000 284.09000 ? 320 HIS B N     1 
ATOM   6482 C  CA    . HIS B 2 320 ? 64.02300  42.98700  9.98100   1.000 283.85000 ? 320 HIS B CA    1 
ATOM   6483 C  C     . HIS B 2 320 ? 64.19000  42.01800  11.11800  1.000 282.30000 ? 320 HIS B C     1 
ATOM   6484 O  O     . HIS B 2 320 ? 63.93000  42.34800  12.27800  1.000 283.57000 ? 320 HIS B O     1 
ATOM   6485 C  CB    . HIS B 2 320 ? 64.94900  44.15700  10.18900  1.000 288.56000 ? 320 HIS B CB    1 
ATOM   6486 C  CG    . HIS B 2 320 ? 64.47900  45.36700  9.47400   1.000 290.96000 ? 320 HIS B CG    1 
ATOM   6487 N  ND1   . HIS B 2 320 ? 65.08800  45.83500  8.32900   1.000 302.51000 ? 320 HIS B ND1   1 
ATOM   6488 C  CD2   . HIS B 2 320 ? 63.37300  46.12400  9.65700   1.000 296.75000 ? 320 HIS B CD2   1 
ATOM   6489 C  CE1   . HIS B 2 320 ? 64.40600  46.86700  7.87200   1.000 308.96000 ? 320 HIS B CE1   1 
ATOM   6490 N  NE2   . HIS B 2 320 ? 63.36200  47.06300  8.66100   1.000 309.68000 ? 320 HIS B NE2   1 
ATOM   6491 N  N     . PHE B 2 321 ? 64.55400  40.81300  10.75600  1.000 290.61000 ? 321 PHE B N     1 
ATOM   6492 C  CA    . PHE B 2 321 ? 64.88300  39.79900  11.73200  1.000 293.44000 ? 321 PHE B CA    1 
ATOM   6493 C  C     . PHE B 2 321 ? 65.89500  40.31700  12.74800  1.000 289.24000 ? 321 PHE B C     1 
ATOM   6494 O  O     . PHE B 2 321 ? 66.94900  40.85400  12.38600  1.000 288.70000 ? 321 PHE B O     1 
ATOM   6495 C  CB    . PHE B 2 321 ? 65.42800  38.57900  10.98500  1.000 301.54000 ? 321 PHE B CB    1 
ATOM   6496 C  CG    . PHE B 2 321 ? 65.65700  37.38700  11.84000  1.000 301.31000 ? 321 PHE B CG    1 
ATOM   6497 C  CD1   . PHE B 2 321 ? 66.85600  37.23500  12.48200  1.000 297.75000 ? 321 PHE B CD1   1 
ATOM   6498 C  CD2   . PHE B 2 321 ? 64.68300  36.41400  11.97800  1.000 299.13000 ? 321 PHE B CD2   1 
ATOM   6499 C  CE1   . PHE B 2 321 ? 67.10300  36.15000  13.24200  1.000 295.61000 ? 321 PHE B CE1   1 
ATOM   6500 C  CE2   . PHE B 2 321 ? 64.91600  35.31900  12.75000  1.000 294.49000 ? 321 PHE B CE2   1 
ATOM   6501 C  CZ    . PHE B 2 321 ? 66.12900  35.19100  13.38600  1.000 295.62000 ? 321 PHE B CZ    1 
ATOM   6502 N  N     . GLY B 2 322 ? 65.53700  40.18700  14.02500  1.000 290.61000 ? 322 GLY B N     1 
ATOM   6503 C  CA    . GLY B 2 322 ? 66.44500  40.49200  15.10600  1.000 297.35000 ? 322 GLY B CA    1 
ATOM   6504 C  C     . GLY B 2 322 ? 66.61600  39.27800  15.99100  1.000 306.22000 ? 322 GLY B C     1 
ATOM   6505 O  O     . GLY B 2 322 ? 65.84200  38.32000  15.90900  1.000 307.18000 ? 322 GLY B O     1 
ATOM   6506 N  N     . ILE B 2 323 ? 67.66200  39.31300  16.82900  1.000 313.44000 ? 323 ILE B N     1 
ATOM   6507 C  CA    . ILE B 2 323 ? 67.95300  38.23000  17.76900  1.000 313.67000 ? 323 ILE B CA    1 
ATOM   6508 C  C     . ILE B 2 323 ? 68.26700  38.81900  19.13900  1.000 309.97000 ? 323 ILE B C     1 
ATOM   6509 O  O     . ILE B 2 323 ? 68.56800  40.00900  19.28400  1.000 315.20000 ? 323 ILE B O     1 
ATOM   6510 C  CB    . ILE B 2 323 ? 69.13900  37.33800  17.33600  1.000 305.51000 ? 323 ILE B CB    1 
ATOM   6511 C  CG1   . ILE B 2 323 ? 70.45900  37.97100  17.81800  1.000 301.00000 ? 323 ILE B CG1   1 
ATOM   6512 C  CG2   . ILE B 2 323 ? 69.13600  37.10000  15.83100  1.000 302.80000 ? 323 ILE B CG2   1 
ATOM   6513 C  CD1   . ILE B 2 323 ? 71.65000  37.04600  17.84400  1.000 296.13000 ? 323 ILE B CD1   1 
ATOM   6514 N  N     . SER B 2 324 ? 68.25000  37.94400  20.14100  1.000 301.55000 ? 324 SER B N     1 
ATOM   6515 C  CA    . SER B 2 324 ? 68.69300  38.28500  21.47900  1.000 299.83000 ? 324 SER B CA    1 
ATOM   6516 C  C     . SER B 2 324 ? 69.67400  37.24100  21.99500  1.000 294.77000 ? 324 SER B C     1 
ATOM   6517 O  O     . SER B 2 324 ? 69.72600  36.10400  21.51400  1.000 285.60000 ? 324 SER B O     1 
ATOM   6518 C  CB    . SER B 2 324 ? 67.50600  38.41600  22.43000  1.000 303.56000 ? 324 SER B CB    1 
ATOM   6519 O  OG    . SER B 2 324 ? 66.47700  37.51400  22.04900  1.000 305.50000 ? 324 SER B OG    1 
ATOM   6520 N  N     . ALA B 2 325 ? 70.44900  37.65800  23.00100  1.000 302.16000 ? 325 ALA B N     1 
ATOM   6521 C  CA    . ALA B 2 325 ? 71.41300  36.80400  23.68700  1.000 301.09000 ? 325 ALA B CA    1 
ATOM   6522 C  C     . ALA B 2 325 ? 71.03800  36.68500  25.15200  1.000 296.26000 ? 325 ALA B C     1 
ATOM   6523 O  O     . ALA B 2 325 ? 71.35500  37.56800  25.95500  1.000 292.80000 ? 325 ALA B O     1 
ATOM   6524 C  CB    . ALA B 2 325 ? 72.83300  37.34000  23.58400  1.000 304.34000 ? 325 ALA B CB    1 
ATOM   6525 N  N     . ALA B 2 326 ? 70.38500  35.59300  25.49400  1.000 303.19000 ? 326 ALA B N     1 
ATOM   6526 C  CA    . ALA B 2 326 ? 70.51700  35.01100  26.81100  1.000 304.04000 ? 326 ALA B CA    1 
ATOM   6527 C  C     . ALA B 2 326 ? 71.73800  34.09900  26.77700  1.000 300.26000 ? 326 ALA B C     1 
ATOM   6528 O  O     . ALA B 2 326 ? 71.91800  33.32000  25.84000  1.000 298.18000 ? 326 ALA B O     1 
ATOM   6529 C  CB    . ALA B 2 326 ? 69.26600  34.20300  27.17800  1.000 306.16000 ? 326 ALA B CB    1 
ATOM   6530 N  N     . GLY B 2 327 ? 72.57700  34.17800  27.80500  1.000 297.55000 ? 327 GLY B N     1 
ATOM   6531 C  CA    . GLY B 2 327 ? 73.58700  33.17000  28.04300  1.000 296.62000 ? 327 GLY B CA    1 
ATOM   6532 C  C     . GLY B 2 327 ? 73.16300  32.35700  29.28300  1.000 305.53000 ? 327 GLY B C     1 
ATOM   6533 O  O     . GLY B 2 327 ? 72.83800  32.94000  30.31100  1.000 314.11000 ? 327 GLY B O     1 
ATOM   6534 N  N     . LYS B 2 328 ? 73.14500  31.04100  29.12900  1.000 297.41000 ? 328 LYS B N     1 
ATOM   6535 C  CA    . LYS B 2 328 ? 72.83500  30.17800  30.27100  1.000 300.53000 ? 328 LYS B CA    1 
ATOM   6536 C  C     . LYS B 2 328 ? 73.99700  29.22500  30.47200  1.000 305.98000 ? 328 LYS B C     1 
ATOM   6537 O  O     . LYS B 2 328 ? 74.59200  28.78000  29.49600  1.000 306.74000 ? 328 LYS B O     1 
ATOM   6538 C  CB    . LYS B 2 328 ? 71.53200  29.38700  30.07200  1.000 299.56000 ? 328 LYS B CB    1 
ATOM   6539 C  CG    . LYS B 2 328 ? 70.92500  28.89300  31.39900  1.000 300.67000 ? 328 LYS B CG    1 
ATOM   6540 C  CD    . LYS B 2 328 ? 69.99600  27.69900  31.22200  1.000 297.44000 ? 328 LYS B CD    1 
ATOM   6541 C  CE    . LYS B 2 328 ? 68.87800  27.67700  32.26700  1.000 309.51000 ? 328 LYS B CE    1 
ATOM   6542 N  NZ    . LYS B 2 328 ? 67.98700  26.48100  32.14200  1.000 299.60000 ? 328 LYS B NZ    1 
ATOM   6543 N  N     . LEU B 2 329 ? 74.32500  28.90500  31.72300  1.000 314.29000 ? 329 LEU B N     1 
ATOM   6544 C  CA    . LEU B 2 329 ? 75.46200  28.01500  31.97600  1.000 316.72000 ? 329 LEU B CA    1 
ATOM   6545 C  C     . LEU B 2 329 ? 75.06400  26.53600  31.93900  1.000 312.74000 ? 329 LEU B C     1 
ATOM   6546 O  O     . LEU B 2 329 ? 75.91200  25.66400  31.72200  1.000 307.28000 ? 329 LEU B O     1 
ATOM   6547 C  CB    . LEU B 2 329 ? 76.09600  28.31900  33.33600  1.000 324.65000 ? 329 LEU B CB    1 
ATOM   6548 C  CG    . LEU B 2 329 ? 76.70400  29.63500  33.82100  1.000 320.83000 ? 329 LEU B CG    1 
ATOM   6549 C  CD1   . LEU B 2 329 ? 77.78500  30.29900  32.88700  1.000 316.12000 ? 329 LEU B CD1   1 
ATOM   6550 C  CD2   . LEU B 2 329 ? 75.64600  30.63800  34.22900  1.000 318.05000 ? 329 LEU B CD2   1 
ATOM   6551 N  N     . TYR B 2 330 ? 73.81000  26.21800  32.20500  1.000 316.72000 ? 330 TYR B N     1 
ATOM   6552 C  CA    . TYR B 2 330 ? 73.45400  24.86000  32.57100  1.000 314.81000 ? 330 TYR B CA    1 
ATOM   6553 C  C     . TYR B 2 330 ? 72.35900  24.34000  31.66500  1.000 309.28000 ? 330 TYR B C     1 
ATOM   6554 O  O     . TYR B 2 330 ? 71.40000  25.06700  31.36300  1.000 312.03000 ? 330 TYR B O     1 
ATOM   6555 C  CB    . TYR B 2 330 ? 72.97200  24.78800  34.02400  1.000 323.48000 ? 330 TYR B CB    1 
ATOM   6556 C  CG    . TYR B 2 330 ? 72.65400  23.38300  34.39600  1.000 318.48000 ? 330 TYR B CG    1 
ATOM   6557 C  CD1   . TYR B 2 330 ? 71.33700  22.91600  34.39400  1.000 311.53000 ? 330 TYR B CD1   1 
ATOM   6558 C  CD2   . TYR B 2 330 ? 73.68400  22.50300  34.71100  1.000 318.85000 ? 330 TYR B CD2   1 
ATOM   6559 C  CE1   . TYR B 2 330 ? 71.06100  21.61700  34.72100  1.000 311.84000 ? 330 TYR B CE1   1 
ATOM   6560 C  CE2   . TYR B 2 330 ? 73.42900  21.20800  35.01500  1.000 321.61000 ? 330 TYR B CE2   1 
ATOM   6561 C  CZ    . TYR B 2 330 ? 72.10900  20.76200  35.03200  1.000 322.19000 ? 330 TYR B CZ    1 
ATOM   6562 O  OH    . TYR B 2 330 ? 71.80800  19.45800  35.36300  1.000 329.73000 ? 330 TYR B OH    1 
ATOM   6563 N  N     . PRO B 2 331 ? 72.43200  23.05300  31.26200  1.000 312.32000 ? 331 PRO B N     1 
ATOM   6564 C  CA    . PRO B 2 331 ? 73.40100  21.98700  31.56400  1.000 304.06000 ? 331 PRO B CA    1 
ATOM   6565 C  C     . PRO B 2 331 ? 74.75800  22.23800  30.95700  1.000 303.62000 ? 331 PRO B C     1 
ATOM   6566 O  O     . PRO B 2 331 ? 75.76800  22.21300  31.66500  1.000 305.44000 ? 331 PRO B O     1 
ATOM   6567 C  CB    . PRO B 2 331 ? 72.76300  20.73800  30.94900  1.000 301.76000 ? 331 PRO B CB    1 
ATOM   6568 C  CG    . PRO B 2 331 ? 71.82700  21.25800  29.90900  1.000 307.42000 ? 331 PRO B CG    1 
ATOM   6569 C  CD    . PRO B 2 331 ? 71.30400  22.57900  30.45700  1.000 316.89000 ? 331 PRO B CD    1 
ATOM   6570 N  N     . SER B 2 332 ? 74.79200  22.46200  29.66500  1.000 295.53000 ? 332 SER B N     1 
ATOM   6571 C  CA    . SER B 2 332 ? 76.01000  22.91200  29.04300  1.000 295.24000 ? 332 SER B CA    1 
ATOM   6572 C  C     . SER B 2 332 ? 75.94700  24.40200  28.82900  1.000 298.67000 ? 332 SER B C     1 
ATOM   6573 O  O     . SER B 2 332 ? 74.90100  24.93800  28.41500  1.000 302.24000 ? 332 SER B O     1 
ATOM   6574 C  CB    . SER B 2 332 ? 76.27300  22.22700  27.71400  1.000 300.90000 ? 332 SER B CB    1 
ATOM   6575 O  OG    . SER B 2 332 ? 76.15600  20.83000  27.88900  1.000 305.78000 ? 332 SER B OG    1 
ATOM   6576 N  N     . PRO B 2 333 ? 77.05200  25.08000  29.11900  1.000 296.75000 ? 333 PRO B N     1 
ATOM   6577 C  CA    . PRO B 2 333 ? 77.09600  26.53000  28.91100  1.000 295.46000 ? 333 PRO B CA    1 
ATOM   6578 C  C     . PRO B 2 333 ? 76.94300  26.88400  27.44300  1.000 296.94000 ? 333 PRO B C     1 
ATOM   6579 O  O     . PRO B 2 333 ? 77.65100  26.34600  26.58600  1.000 296.08000 ? 333 PRO B O     1 
ATOM   6580 C  CB    . PRO B 2 333 ? 78.46300  26.93000  29.45400  1.000 299.68000 ? 333 PRO B CB    1 
ATOM   6581 C  CG    . PRO B 2 333 ? 78.79300  25.80500  30.43600  1.000 304.41000 ? 333 PRO B CG    1 
ATOM   6582 C  CD    . PRO B 2 333 ? 78.20700  24.55600  29.86400  1.000 298.89000 ? 333 PRO B CD    1 
ATOM   6583 N  N     . VAL B 2 334 ? 75.96300  27.75300  27.15900  1.000 298.53000 ? 334 VAL B N     1 
ATOM   6584 C  CA    . VAL B 2 334 ? 75.58200  28.09900  25.78300  1.000 296.59000 ? 334 VAL B CA    1 
ATOM   6585 C  C     . VAL B 2 334 ? 75.18800  29.56600  25.74000  1.000 283.56000 ? 334 VAL B C     1 
ATOM   6586 O  O     . VAL B 2 334 ? 74.90600  30.17600  26.76000  1.000 286.40000 ? 334 VAL B O     1 
ATOM   6587 C  CB    . VAL B 2 334 ? 74.40500  27.23000  25.26700  1.000 304.94000 ? 334 VAL B CB    1 
ATOM   6588 C  CG1   . VAL B 2 334 ? 74.81400  25.76100  25.27000  1.000 300.57000 ? 334 VAL B CG1   1 
ATOM   6589 C  CG2   . VAL B 2 334 ? 73.14500  27.48000  26.14000  1.000 304.52000 ? 334 VAL B CG2   1 
ATOM   6590 N  N     . LEU B 2 335 ? 75.11300  30.11800  24.54700  1.000 290.50000 ? 335 LEU B N     1 
ATOM   6591 C  CA    . LEU B 2 335 ? 74.41000  31.36900  24.33400  1.000 291.49000 ? 335 LEU B CA    1 
ATOM   6592 C  C     . LEU B 2 335 ? 73.04300  31.07100  23.73100  1.000 296.21000 ? 335 LEU B C     1 
ATOM   6593 O  O     . LEU B 2 335 ? 72.95900  30.54000  22.62000  1.000 297.35000 ? 335 LEU B O     1 
ATOM   6594 C  CB    . LEU B 2 335 ? 75.17800  32.27700  23.39000  1.000 293.59000 ? 335 LEU B CB    1 
ATOM   6595 C  CG    . LEU B 2 335 ? 74.19800  33.42400  23.48700  1.000 298.47000 ? 335 LEU B CG    1 
ATOM   6596 C  CD1   . LEU B 2 335 ? 74.58900  34.16800  24.72900  1.000 291.94000 ? 335 LEU B CD1   1 
ATOM   6597 C  CD2   . LEU B 2 335 ? 74.14500  34.31800  22.26000  1.000 314.18000 ? 335 LEU B CD2   1 
ATOM   6598 N  N     . MET B 2 336 ? 71.97500  31.46200  24.41400  1.000 297.06000 ? 336 MET B N     1 
ATOM   6599 C  CA    . MET B 2 336 ? 70.63400  31.27400  23.86600  1.000 297.60000 ? 336 MET B CA    1 
ATOM   6600 C  C     . MET B 2 336 ? 70.30200  32.41900  22.91900  1.000 290.53000 ? 336 MET B C     1 
ATOM   6601 O  O     . MET B 2 336 ? 70.67500  33.57200  23.16400  1.000 291.04000 ? 336 MET B O     1 
ATOM   6602 C  CB    . MET B 2 336 ? 69.56100  31.21100  24.96300  1.000 304.67000 ? 336 MET B CB    1 
ATOM   6603 C  CG    . MET B 2 336 ? 69.82200  30.27400  26.15200  1.000 308.72000 ? 336 MET B CG    1 
ATOM   6604 S  SD    . MET B 2 336 ? 68.33000  30.20900  27.19000  1.000 308.30000 ? 336 MET B SD    1 
ATOM   6605 C  CE    . MET B 2 336 ? 68.55700  28.71200  28.18700  1.000 309.37000 ? 336 MET B CE    1 
ATOM   6606 N  N     . VAL B 2 337 ? 69.58700  32.11400  21.84600  1.000 277.80000 ? 337 VAL B N     1 
ATOM   6607 C  CA    . VAL B 2 337 ? 69.17800  33.14300  20.91000  1.000 283.79000 ? 337 VAL B CA    1 
ATOM   6608 C  C     . VAL B 2 337 ? 67.69100  33.01600  20.65200  1.000 284.84000 ? 337 VAL B C     1 
ATOM   6609 O  O     . VAL B 2 337 ? 67.23900  32.07600  19.98600  1.000 283.70000 ? 337 VAL B O     1 
ATOM   6610 C  CB    . VAL B 2 337 ? 69.97700  33.07500  19.61200  1.000 284.73000 ? 337 VAL B CB    1 
ATOM   6611 C  CG1   . VAL B 2 337 ? 69.92600  34.38800  18.94500  1.000 283.10000 ? 337 VAL B CG1   1 
ATOM   6612 C  CG2   . VAL B 2 337 ? 71.38600  32.75100  19.93200  1.000 281.12000 ? 337 VAL B CG2   1 
ATOM   6613 N  N     . SER B 2 338 ? 66.93300  33.95600  21.19100  1.000 286.68000 ? 338 SER B N     1 
ATOM   6614 C  CA    . SER B 2 338 ? 65.51400  34.07700  20.91000  1.000 287.81000 ? 338 SER B CA    1 
ATOM   6615 C  C     . SER B 2 338 ? 65.33600  34.99500  19.72800  1.000 287.78000 ? 338 SER B C     1 
ATOM   6616 O  O     . SER B 2 338 ? 66.00700  36.02200  19.61400  1.000 289.26000 ? 338 SER B O     1 
ATOM   6617 C  CB    . SER B 2 338 ? 64.73200  34.64000  22.09400  1.000 301.66000 ? 338 SER B CB    1 
ATOM   6618 O  OG    . SER B 2 338 ? 63.79000  33.68300  22.55200  1.000 319.97000 ? 338 SER B OG    1 
ATOM   6619 N  N     . SER B 2 339 ? 64.41700  34.63500  18.87000  1.000 282.53000 ? 339 SER B N     1 
ATOM   6620 C  CA    . SER B 2 339 ? 64.26400  35.35300  17.63300  1.000 289.20000 ? 339 SER B CA    1 
ATOM   6621 C  C     . SER B 2 339 ? 63.22500  36.44500  17.82000  1.000 294.33000 ? 339 SER B C     1 
ATOM   6622 O  O     . SER B 2 339 ? 62.38800  36.38700  18.72600  1.000 287.60000 ? 339 SER B O     1 
ATOM   6623 C  CB    . SER B 2 339 ? 63.89000  34.36300  16.54300  1.000 288.84000 ? 339 SER B CB    1 
ATOM   6624 O  OG    . SER B 2 339 ? 64.50600  33.11600  16.85600  1.000 286.52000 ? 339 SER B OG    1 
ATOM   6625 N  N     . HIS B 2 340 ? 63.34100  37.48900  17.01100  1.000 300.56000 ? 340 HIS B N     1 
ATOM   6626 C  CA    . HIS B 2 340 ? 62.45500  38.62600  17.13500  1.000 295.24000 ? 340 HIS B CA    1 
ATOM   6627 C  C     . HIS B 2 340 ? 62.08800  39.13400  15.76800  1.000 285.55000 ? 340 HIS B C     1 
ATOM   6628 O  O     . HIS B 2 340 ? 62.68400  38.77300  14.74800  1.000 285.57000 ? 340 HIS B O     1 
ATOM   6629 C  CB    . HIS B 2 340 ? 63.07500  39.80400  17.88500  1.000 295.48000 ? 340 HIS B CB    1 
ATOM   6630 C  CG    . HIS B 2 340 ? 63.31900  39.55900  19.33700  1.000 293.73000 ? 340 HIS B CG    1 
ATOM   6631 N  ND1   . HIS B 2 340 ? 63.85300  38.38700  19.82600  1.000 290.58000 ? 340 HIS B ND1   1 
ATOM   6632 C  CD2   . HIS B 2 340 ? 63.12900  40.36100  20.40700  1.000 295.96000 ? 340 HIS B CD2   1 
ATOM   6633 C  CE1   . HIS B 2 340 ? 63.96100  38.47000  21.13600  1.000 291.02000 ? 340 HIS B CE1   1 
ATOM   6634 N  NE2   . HIS B 2 340 ? 63.53300  39.65900  21.51300  1.000 299.29000 ? 340 HIS B NE2   1 
ATOM   6635 N  N     . ILE B 2 341 ? 61.12500  40.03400  15.76700  1.000 284.06000 ? 341 ILE B N     1 
ATOM   6636 C  CA    . ILE B 2 341 ? 60.80000  40.74800  14.56500  1.000 283.74000 ? 341 ILE B CA    1 
ATOM   6637 C  C     . ILE B 2 341 ? 60.64700  42.21300  14.93100  1.000 289.36000 ? 341 ILE B C     1 
ATOM   6638 O  O     . ILE B 2 341 ? 59.66600  42.62300  15.56700  1.000 295.20000 ? 341 ILE B O     1 
ATOM   6639 C  CB    . ILE B 2 341 ? 59.56500  40.18300  13.87300  1.000 290.98000 ? 341 ILE B CB    1 
ATOM   6640 C  CG1   . ILE B 2 341 ? 59.60900  38.64600  13.90100  1.000 285.14000 ? 341 ILE B CG1   1 
ATOM   6641 C  CG2   . ILE B 2 341 ? 59.58300  40.61900  12.42400  1.000 306.75000 ? 341 ILE B CG2   1 
ATOM   6642 C  CD1   . ILE B 2 341 ? 58.45800  37.99800  13.13100  1.000 291.09000 ? 341 ILE B CD1   1 
ATOM   6643 N  N     . ILE B 2 342 ? 61.64600  42.98800  14.53900  1.000 282.43000 ? 342 ILE B N     1 
ATOM   6644 C  CA    . ILE B 2 342 ? 61.68700  44.43600  14.66500  1.000 283.50000 ? 342 ILE B CA    1 
ATOM   6645 C  C     . ILE B 2 342 ? 60.98700  45.04200  13.47200  1.000 289.80000 ? 342 ILE B C     1 
ATOM   6646 O  O     . ILE B 2 342 ? 60.69000  44.33500  12.50900  1.000 294.42000 ? 342 ILE B O     1 
ATOM   6647 C  CB    . ILE B 2 342 ? 63.13100  44.93800  14.72600  1.000 288.35000 ? 342 ILE B CB    1 
ATOM   6648 C  CG1   . ILE B 2 342 ? 64.00800  43.84800  15.31900  1.000 290.26000 ? 342 ILE B CG1   1 
ATOM   6649 C  CG2   . ILE B 2 342 ? 63.20200  46.22900  15.51800  1.000 299.99000 ? 342 ILE B CG2   1 
ATOM   6650 C  CD1   . ILE B 2 342 ? 63.65800  43.47900  16.74600  1.000 287.11000 ? 342 ILE B CD1   1 
ATOM   6651 N  N     . PHE B 2 343 ? 60.74000  46.34900  13.50100  1.000 285.78000 ? 343 PHE B N     1 
ATOM   6652 C  CA    . PHE B 2 343 ? 59.98800  46.95800  12.42100  1.000 292.68000 ? 343 PHE B CA    1 
ATOM   6653 C  C     . PHE B 2 343 ? 60.34600  48.40800  12.23800  1.000 298.78000 ? 343 PHE B C     1 
ATOM   6654 O  O     . PHE B 2 343 ? 60.60700  49.13400  13.20900  1.000 297.26000 ? 343 PHE B O     1 
ATOM   6655 C  CB    . PHE B 2 343 ? 58.51200  46.87100  12.70700  1.000 300.70000 ? 343 PHE B CB    1 
ATOM   6656 C  CG    . PHE B 2 343 ? 57.95200  45.54200  12.41000  1.000 302.85000 ? 343 PHE B CG    1 
ATOM   6657 C  CD1   . PHE B 2 343 ? 57.56200  45.24800  11.11600  1.000 309.52000 ? 343 PHE B CD1   1 
ATOM   6658 C  CD2   . PHE B 2 343 ? 57.84900  44.58000  13.43700  1.000 297.42000 ? 343 PHE B CD2   1 
ATOM   6659 C  CE1   . PHE B 2 343 ? 57.03600  43.96400  10.80400  1.000 315.45000 ? 343 PHE B CE1   1 
ATOM   6660 C  CE2   . PHE B 2 343 ? 57.30500  43.33200  13.20000  1.000 300.93000 ? 343 PHE B CE2   1 
ATOM   6661 C  CZ    . PHE B 2 343 ? 56.92700  43.01500  11.83300  1.000 312.39000 ? 343 PHE B CZ    1 
ATOM   6662 N  N     . THR B 2 344 ? 60.25000  48.81000  10.98200  1.000 299.77000 ? 344 THR B N     1 
ATOM   6663 C  CA    . THR B 2 344 ? 60.65600  50.10500  10.50200  1.000 298.26000 ? 344 THR B CA    1 
ATOM   6664 C  C     . THR B 2 344 ? 59.75200  50.42700  9.32400   1.000 302.11000 ? 344 THR B C     1 
ATOM   6665 O  O     . THR B 2 344 ? 59.52500  49.56600  8.46200   1.000 302.24000 ? 344 THR B O     1 
ATOM   6666 C  CB    . THR B 2 344 ? 62.13800  50.07300  10.10300  1.000 301.55000 ? 344 THR B CB    1 
ATOM   6667 O  OG1   . THR B 2 344 ? 62.55700  48.72300  9.89800   1.000 302.56000 ? 344 THR B OG1   1 
ATOM   6668 C  CG2   . THR B 2 344 ? 63.05700  50.68100  11.16200  1.000 300.46000 ? 344 THR B CG2   1 
ATOM   6669 N  N     . MET B 2 345 ? 59.19600  51.64300  9.31700   1.000 307.88000 ? 345 MET B N     1 
ATOM   6670 C  CA    . MET B 2 345 ? 58.44800  52.08100  8.14600   1.000 309.66000 ? 345 MET B CA    1 
ATOM   6671 C  C     . MET B 2 345 ? 59.40400  52.42100  7.01600   1.000 306.73000 ? 345 MET B C     1 
ATOM   6672 O  O     . MET B 2 345 ? 59.05100  52.31900  5.83500   1.000 308.11000 ? 345 MET B O     1 
ATOM   6673 C  CB    . MET B 2 345 ? 57.59500  53.30300  8.49900   1.000 317.59000 ? 345 MET B CB    1 
ATOM   6674 C  CG    . MET B 2 345 ? 58.40700  54.35600  9.21600   1.000 320.08000 ? 345 MET B CG    1 
ATOM   6675 S  SD    . MET B 2 345 ? 57.63300  55.98100  9.37400   1.000 342.42000 ? 345 MET B SD    1 
ATOM   6676 C  CE    . MET B 2 345 ? 56.59900  55.73700  10.81700  1.000 301.59000 ? 345 MET B CE    1 
ATOM   6677 N  N     . ASP B 2 346 ? 60.62700  52.80900  7.37000   1.000 302.74000 ? 346 ASP B N     1 
ATOM   6678 C  CA    . ASP B 2 346 ? 61.67300  53.07700  6.40800   1.000 297.98000 ? 346 ASP B CA    1 
ATOM   6679 C  C     . ASP B 2 346 ? 62.92500  52.32600  6.81900   1.000 300.35000 ? 346 ASP B C     1 
ATOM   6680 O  O     . ASP B 2 346 ? 63.06900  51.90900  7.97100   1.000 306.34000 ? 346 ASP B O     1 
ATOM   6681 C  CB    . ASP B 2 346 ? 61.98400  54.56100  6.31300   1.000 298.78000 ? 346 ASP B CB    1 
ATOM   6682 C  CG    . ASP B 2 346 ? 62.23400  55.15500  7.65600   1.000 310.96000 ? 346 ASP B CG    1 
ATOM   6683 O  OD1   . ASP B 2 346 ? 63.14700  54.68000  8.36500   1.000 311.09000 ? 346 ASP B OD1   1 
ATOM   6684 O  OD2   . ASP B 2 346 ? 61.48900  56.08200  8.00600   1.000 315.36000 ? 346 ASP B OD2   1 
ATOM   6685 N  N     . GLY B 2 347 ? 63.86900  52.27000  5.87300   1.000 301.77000 ? 347 GLY B N     1 
ATOM   6686 C  CA    . GLY B 2 347 ? 64.98600  51.33700  5.96900   1.000 301.08000 ? 347 GLY B CA    1 
ATOM   6687 C  C     . GLY B 2 347 ? 65.60200  51.21900  7.35800   1.000 305.64000 ? 347 GLY B C     1 
ATOM   6688 O  O     . GLY B 2 347 ? 65.95300  50.11900  7.80200   1.000 307.37000 ? 347 GLY B O     1 
ATOM   6689 N  N     . ILE B 2 348 ? 65.77600  52.33900  8.05600   1.000 309.83000 ? 348 ILE B N     1 
ATOM   6690 C  CA    . ILE B 2 348 ? 66.69900  52.35800  9.18200   1.000 316.90000 ? 348 ILE B CA    1 
ATOM   6691 C  C     . ILE B 2 348 ? 66.16500  53.17000  10.36000  1.000 317.74000 ? 348 ILE B C     1 
ATOM   6692 O  O     . ILE B 2 348 ? 66.85400  53.27500  11.37000  1.000 322.02000 ? 348 ILE B O     1 
ATOM   6693 C  CB    . ILE B 2 348 ? 68.08700  52.89000  8.75400   1.000 322.08000 ? 348 ILE B CB    1 
ATOM   6694 C  CG1   . ILE B 2 348 ? 67.87500  54.20700  8.02100   1.000 319.22000 ? 348 ILE B CG1   1 
ATOM   6695 C  CG2   . ILE B 2 348 ? 68.92400  51.81900  7.85800   1.000 320.72000 ? 348 ILE B CG2   1 
ATOM   6696 C  CD1   . ILE B 2 348 ? 69.05300  55.17300  8.20400   1.000 318.91000 ? 348 ILE B CD1   1 
ATOM   6697 N  N     . ASN B 2 349 ? 64.94200  53.72700  10.29200  1.000 309.10000 ? 349 ASN B N     1 
ATOM   6698 C  CA    . ASN B 2 349 ? 64.39100  54.54600  11.38300  1.000 310.49000 ? 349 ASN B CA    1 
ATOM   6699 C  C     . ASN B 2 349 ? 63.26500  53.80300  12.09500  1.000 308.38000 ? 349 ASN B C     1 
ATOM   6700 O  O     . ASN B 2 349 ? 62.20200  53.55300  11.50900  1.000 309.34000 ? 349 ASN B O     1 
ATOM   6701 C  CB    . ASN B 2 349 ? 63.94400  55.91500  10.86900  1.000 310.40000 ? 349 ASN B CB    1 
ATOM   6702 C  CG    . ASN B 2 349 ? 65.01500  56.96800  11.08900  1.000 313.13000 ? 349 ASN B CG    1 
ATOM   6703 O  OD1   . ASN B 2 349 ? 65.85500  56.80300  11.96100  1.000 317.37000 ? 349 ASN B OD1   1 
ATOM   6704 N  ND2   . ASN B 2 349 ? 65.00900  58.03200  10.29300  1.000 300.09000 ? 349 ASN B ND2   1 
ATOM   6705 N  N     . LEU B 2 350 ? 63.50700  53.48600  13.36800  1.000 298.28000 ? 350 LEU B N     1 
ATOM   6706 C  CA    . LEU B 2 350 ? 62.73000  52.47800  14.06500  1.000 293.74000 ? 350 LEU B CA    1 
ATOM   6707 C  C     . LEU B 2 350 ? 61.36500  53.02700  14.42600  1.000 293.00000 ? 350 LEU B C     1 
ATOM   6708 O  O     . LEU B 2 350 ? 61.19900  54.21100  14.74100  1.000 295.17000 ? 350 LEU B O     1 
ATOM   6709 C  CB    . LEU B 2 350 ? 63.43100  51.98400  15.33000  1.000 285.47000 ? 350 LEU B CB    1 
ATOM   6710 C  CG    . LEU B 2 350 ? 64.94000  52.06900  15.55800  1.000 291.02000 ? 350 LEU B CG    1 
ATOM   6711 C  CD1   . LEU B 2 350 ? 65.71300  51.77500  14.34300  1.000 293.25000 ? 350 LEU B CD1   1 
ATOM   6712 C  CD2   . LEU B 2 350 ? 65.34200  53.42900  16.03500  1.000 287.18000 ? 350 LEU B CD2   1 
ATOM   6713 N  N     . ILE B 2 351 ? 60.37600  52.14300  14.35800  1.000 291.54000 ? 351 ILE B N     1 
ATOM   6714 C  CA    . ILE B 2 351 ? 59.00800  52.54600  14.62700  1.000 295.18000 ? 351 ILE B CA    1 
ATOM   6715 C  C     . ILE B 2 351 ? 58.87400  52.97000  16.08900  1.000 308.91000 ? 351 ILE B C     1 
ATOM   6716 O  O     . ILE B 2 351 ? 59.61900  52.51600  16.96500  1.000 307.07000 ? 351 ILE B O     1 
ATOM   6717 C  CB    . ILE B 2 351 ? 58.05500  51.40500  14.24300  1.000 295.46000 ? 351 ILE B CB    1 
ATOM   6718 C  CG1   . ILE B 2 351 ? 58.15000  51.14500  12.74900  1.000 292.20000 ? 351 ILE B CG1   1 
ATOM   6719 C  CG2   . ILE B 2 351 ? 56.63400  51.75900  14.55700  1.000 302.55000 ? 351 ILE B CG2   1 
ATOM   6720 C  CD1   . ILE B 2 351 ? 57.36300  52.17500  11.86800  1.000 291.08000 ? 351 ILE B CD1   1 
ATOM   6721 N  N     . LYS B 2 352 ? 57.96000  53.90000  16.34800  1.000 314.48000 ? 352 LYS B N     1 
ATOM   6722 C  CA    . LYS B 2 352 ? 57.91400  54.57400  17.63700  1.000 307.41000 ? 352 LYS B CA    1 
ATOM   6723 C  C     . LYS B 2 352 ? 57.16200  53.74000  18.66700  1.000 302.74000 ? 352 LYS B C     1 
ATOM   6724 O  O     . LYS B 2 352 ? 57.70100  53.41000  19.72300  1.000 299.70000 ? 352 LYS B O     1 
ATOM   6725 C  CB    . LYS B 2 352 ? 57.26400  55.92800  17.46500  1.000 300.67000 ? 352 LYS B CB    1 
ATOM   6726 C  CG    . LYS B 2 352 ? 57.15900  56.71700  18.75400  1.000 301.12000 ? 352 LYS B CG    1 
ATOM   6727 C  CD    . LYS B 2 352 ? 56.67700  58.13200  18.48900  1.000 300.35000 ? 352 LYS B CD    1 
ATOM   6728 C  CE    . LYS B 2 352 ? 57.17100  59.09900  19.56200  1.000 300.21000 ? 352 LYS B CE    1 
ATOM   6729 N  NZ    . LYS B 2 352 ? 56.96700  60.53900  19.20200  1.000 293.50000 ? 352 LYS B NZ    1 
ATOM   6730 N  N     . SER B 2 353 ? 55.92300  53.36000  18.36600  1.000 305.76000 ? 353 SER B N     1 
ATOM   6731 C  CA    . SER B 2 353 ? 55.01500  52.73400  19.32800  1.000 305.24000 ? 353 SER B CA    1 
ATOM   6732 C  C     . SER B 2 353 ? 54.94600  51.22400  19.13300  1.000 304.10000 ? 353 SER B C     1 
ATOM   6733 O  O     . SER B 2 353 ? 54.57300  50.73000  18.06300  1.000 304.56000 ? 353 SER B O     1 
ATOM   6734 C  CB    . SER B 2 353 ? 53.59900  53.32600  19.23900  1.000 305.66000 ? 353 SER B CB    1 
ATOM   6735 O  OG    . SER B 2 353 ? 53.02900  53.36000  20.49400  1.000 301.03000 ? 353 SER B OG    1 
ATOM   6736 N  N     . LYS B 2 354 ? 55.20400  50.51300  20.21800  1.000 294.41000 ? 354 LYS B N     1 
ATOM   6737 C  CA    . LYS B 2 354 ? 55.25500  49.06600  20.18800  1.000 288.48000 ? 354 LYS B CA    1 
ATOM   6738 C  C     . LYS B 2 354 ? 53.88400  48.48200  19.90000  1.000 291.67000 ? 354 LYS B C     1 
ATOM   6739 O  O     . LYS B 2 354 ? 53.77800  47.36000  19.38800  1.000 291.15000 ? 354 LYS B O     1 
ATOM   6740 C  CB    . LYS B 2 354 ? 55.82100  48.58800  21.52000  1.000 288.27000 ? 354 LYS B CB    1 
ATOM   6741 C  CG    . LYS B 2 354 ? 56.65000  49.69100  22.22600  1.000 290.59000 ? 354 LYS B CG    1 
ATOM   6742 C  CD    . LYS B 2 354 ? 55.78500  50.58400  23.12100  1.000 302.95000 ? 354 LYS B CD    1 
ATOM   6743 C  CE    . LYS B 2 354 ? 56.63600  51.67700  23.76600  1.000 304.91000 ? 354 LYS B CE    1 
ATOM   6744 N  NZ    . LYS B 2 354 ? 56.05600  52.12400  25.07300  1.000 304.16000 ? 354 LYS B NZ    1 
ATOM   6745 N  N     . SER B 2 355 ? 52.82100  49.22200  20.23700  1.000 292.22000 ? 355 SER B N     1 
ATOM   6746 C  CA    . SER B 2 355 ? 51.48400  48.75000  19.91400  1.000 292.61000 ? 355 SER B CA    1 
ATOM   6747 C  C     . SER B 2 355 ? 51.38700  48.42000  18.44400  1.000 294.62000 ? 355 SER B C     1 
ATOM   6748 O  O     . SER B 2 355 ? 50.84000  47.37600  18.07200  1.000 294.40000 ? 355 SER B O     1 
ATOM   6749 C  CB    . SER B 2 355 ? 50.42600  49.78300  20.29600  1.000 288.27000 ? 355 SER B CB    1 
ATOM   6750 O  OG    . SER B 2 355 ? 49.19100  49.46600  19.66100  1.000 298.68000 ? 355 SER B OG    1 
ATOM   6751 N  N     . ILE B 2 356 ? 51.92900  49.29000  17.59200  1.000 303.39000 ? 356 ILE B N     1 
ATOM   6752 C  CA    . ILE B 2 356 ? 52.04400  48.92400  16.18800  1.000 311.46000 ? 356 ILE B CA    1 
ATOM   6753 C  C     . ILE B 2 356 ? 53.00000  47.73700  16.05400  1.000 308.37000 ? 356 ILE B C     1 
ATOM   6754 O  O     . ILE B 2 356 ? 52.75900  46.80000  15.27600  1.000 313.18000 ? 356 ILE B O     1 
ATOM   6755 C  CB    . ILE B 2 356 ? 52.47300  50.14900  15.33800  1.000 319.38000 ? 356 ILE B CB    1 
ATOM   6756 C  CG1   . ILE B 2 356 ? 52.21500  51.48400  16.07200  1.000 319.37000 ? 356 ILE B CG1   1 
ATOM   6757 C  CG2   . ILE B 2 356 ? 51.73000  50.13000  13.95500  1.000 305.20000 ? 356 ILE B CG2   1 
ATOM   6758 C  CD1   . ILE B 2 356 ? 53.09300  52.73000  15.63200  1.000 319.10000 ? 356 ILE B CD1   1 
ATOM   6759 N  N     . GLN B 2 357 ? 54.05200  47.71400  16.88100  1.000 301.01000 ? 357 GLN B N     1 
ATOM   6760 C  CA    . GLN B 2 357 ? 55.09000  46.69700  16.72600  1.000 293.06000 ? 357 GLN B CA    1 
ATOM   6761 C  C     . GLN B 2 357 ? 54.57900  45.32300  17.08900  1.000 291.16000 ? 357 GLN B C     1 
ATOM   6762 O  O     . GLN B 2 357 ? 54.92600  44.31600  16.44600  1.000 287.78000 ? 357 GLN B O     1 
ATOM   6763 C  CB    . GLN B 2 357 ? 56.26700  47.04400  17.60300  1.000 285.67000 ? 357 GLN B CB    1 
ATOM   6764 C  CG    . GLN B 2 357 ? 57.09600  48.11900  17.02200  1.000 291.41000 ? 357 GLN B CG    1 
ATOM   6765 C  CD    . GLN B 2 357 ? 58.51500  47.68300  16.93700  1.000 294.70000 ? 357 GLN B CD    1 
ATOM   6766 O  OE1   . GLN B 2 357 ? 59.27800  47.92500  17.85700  1.000 305.41000 ? 357 GLN B OE1   1 
ATOM   6767 N  NE2   . GLN B 2 357 ? 58.88300  47.00800  15.84500  1.000 288.49000 ? 357 GLN B NE2   1 
ATOM   6768 N  N     . HIS B 2 358 ? 53.77400  45.28200  18.14700  1.000 292.54000 ? 358 HIS B N     1 
ATOM   6769 C  CA    . HIS B 2 358 ? 53.09800  44.07700  18.57200  1.000 291.44000 ? 358 HIS B CA    1 
ATOM   6770 C  C     . HIS B 2 358 ? 52.14800  43.59400  17.50100  1.000 293.01000 ? 358 HIS B C     1 
ATOM   6771 O  O     . HIS B 2 358 ? 52.33700  42.50800  16.94600  1.000 291.05000 ? 358 HIS B O     1 
ATOM   6772 C  CB    . HIS B 2 358 ? 52.34300  44.38300  19.85800  1.000 299.79000 ? 358 HIS B CB    1 
ATOM   6773 C  CG    . HIS B 2 358 ? 53.19500  45.02000  20.90200  1.000 295.15000 ? 358 HIS B CG    1 
ATOM   6774 N  ND1   . HIS B 2 358 ? 52.68900  45.84500  21.88100  1.000 304.66000 ? 358 HIS B ND1   1 
ATOM   6775 C  CD2   . HIS B 2 358 ? 54.52500  44.94400  21.12100  1.000 295.09000 ? 358 HIS B CD2   1 
ATOM   6776 C  CE1   . HIS B 2 358 ? 53.67000  46.23800  22.66900  1.000 302.74000 ? 358 HIS B CE1   1 
ATOM   6777 N  NE2   . HIS B 2 358 ? 54.79500  45.70500  22.22900  1.000 295.03000 ? 358 HIS B NE2   1 
ATOM   6778 N  N     . SER B 2 359 ? 51.15000  44.40200  17.15300  1.000 299.64000 ? 359 SER B N     1 
ATOM   6779 C  CA    . SER B 2 359 ? 50.28500  44.00500  16.04900  1.000 296.62000 ? 359 SER B CA    1 
ATOM   6780 C  C     . SER B 2 359 ? 51.10700  43.52700  14.80900  1.000 299.05000 ? 359 SER B C     1 
ATOM   6781 O  O     . SER B 2 359 ? 50.77400  42.44900  14.25800  1.000 300.62000 ? 359 SER B O     1 
ATOM   6782 C  CB    . SER B 2 359 ? 49.37900  45.18300  15.68200  1.000 300.15000 ? 359 SER B CB    1 
ATOM   6783 O  OG    . SER B 2 359 ? 50.05500  46.02400  14.72400  1.000 309.13000 ? 359 SER B OG    1 
ATOM   6784 N  N     . SER B 2 360 ? 52.22200  44.27800  14.38100  1.000 308.90000 ? 360 SER B N     1 
ATOM   6785 C  CA    . SER B 2 360 ? 53.04500  43.85400  13.19900  1.000 307.76000 ? 360 SER B CA    1 
ATOM   6786 C  C     . SER B 2 360 ? 53.71600  42.49500  13.48600  1.000 298.06000 ? 360 SER B C     1 
ATOM   6787 O  O     . SER B 2 360 ? 53.81600  41.61600  12.60300  1.000 294.48000 ? 360 SER B O     1 
ATOM   6788 C  CB    . SER B 2 360 ? 54.10500  44.90100  12.78000  1.000 318.13000 ? 360 SER B CB    1 
ATOM   6789 O  OG    . SER B 2 360 ? 54.15100  45.25200  11.61500  1.000 316.12000 ? 360 SER B OG    1 
ATOM   6790 N  N     . ARG B 2 361 ? 54.30200  42.36600  14.68300  1.000 299.94000 ? 361 ARG B N     1 
ATOM   6791 C  CA    . ARG B 2 361 ? 55.00100  41.14900  15.00800  1.000 293.13000 ? 361 ARG B CA    1 
ATOM   6792 C  C     . ARG B 2 361 ? 54.05400  39.99500  14.90100  1.000 289.48000 ? 361 ARG B C     1 
ATOM   6793 O  O     . ARG B 2 361 ? 54.38000  38.98200  14.27900  1.000 285.71000 ? 361 ARG B O     1 
ATOM   6794 C  CB    . ARG B 2 361 ? 55.56400  41.24800  16.39700  1.000 289.09000 ? 361 ARG B CB    1 
ATOM   6795 C  CG    . ARG B 2 361 ? 56.04900  39.87000  16.85800  1.000 292.51000 ? 361 ARG B CG    1 
ATOM   6796 C  CD    . ARG B 2 361 ? 57.01100  39.22800  15.86400  1.000 282.48000 ? 361 ARG B CD    1 
ATOM   6797 N  NE    . ARG B 2 361 ? 57.90200  38.27600  16.47900  1.000 285.90000 ? 361 ARG B NE    1 
ATOM   6798 C  CZ    . ARG B 2 361 ? 57.53400  37.06000  16.84100  1.000 289.66000 ? 361 ARG B CZ    1 
ATOM   6799 N  NH1   . ARG B 2 361 ? 56.28200  36.67000  16.65300  1.000 287.39000 ? 361 ARG B NH1   1 
ATOM   6800 N  NH2   . ARG B 2 361 ? 58.41200  36.24700  17.41000  1.000 306.23000 ? 361 ARG B NH2   1 
ATOM   6801 N  N     . ARG B 2 362 ? 52.83700  40.17000  15.41500  1.000 294.45000 ? 362 ARG B N     1 
ATOM   6802 C  CA    . ARG B 2 362 ? 51.86700  39.11200  15.23000  1.000 298.09000 ? 362 ARG B CA    1 
ATOM   6803 C  C     . ARG B 2 362 ? 51.52100  38.93900  13.76500  1.000 301.36000 ? 362 ARG B C     1 
ATOM   6804 O  O     . ARG B 2 362 ? 51.50600  37.80600  13.26600  1.000 303.04000 ? 362 ARG B O     1 
ATOM   6805 C  CB    . ARG B 2 362 ? 50.61600  39.37800  16.05400  1.000 296.88000 ? 362 ARG B CB    1 
ATOM   6806 C  CG    . ARG B 2 362 ? 50.42500  38.34700  17.14400  1.000 300.39000 ? 362 ARG B CG    1 
ATOM   6807 C  CD    . ARG B 2 362 ? 51.78600  38.04600  17.75500  1.000 310.11000 ? 362 ARG B CD    1 
ATOM   6808 N  NE    . ARG B 2 362 ? 52.22600  39.14500  18.60700  1.000 318.88000 ? 362 ARG B NE    1 
ATOM   6809 C  CZ    . ARG B 2 362 ? 53.28700  39.10500  19.40800  1.000 320.02000 ? 362 ARG B CZ    1 
ATOM   6810 N  NH1   . ARG B 2 362 ? 54.04000  38.01500  19.45800  1.000 322.03000 ? 362 ARG B NH1   1 
ATOM   6811 N  NH2   . ARG B 2 362 ? 53.59400  40.15800  20.16400  1.000 326.38000 ? 362 ARG B NH2   1 
ATOM   6812 N  N     . LYS B 2 363 ? 51.27000  40.04100  13.04800  1.000 293.48000 ? 363 LYS B N     1 
ATOM   6813 C  CA    . LYS B 2 363 ? 50.84600  39.90500  11.65800  1.000 291.53000 ? 363 LYS B CA    1 
ATOM   6814 C  C     . LYS B 2 363 ? 51.90400  39.19100  10.83100  1.000 285.27000 ? 363 LYS B C     1 
ATOM   6815 O  O     . LYS B 2 363 ? 51.58600  38.26100  10.07200  1.000 290.00000 ? 363 LYS B O     1 
ATOM   6816 C  CB    . LYS B 2 363 ? 50.51800  41.27600  11.05100  1.000 293.07000 ? 363 LYS B CB    1 
ATOM   6817 C  CG    . LYS B 2 363 ? 49.15300  41.34900  10.32300  1.000 294.86000 ? 363 LYS B CG    1 
ATOM   6818 C  CD    . LYS B 2 363 ? 48.53400  42.75000  10.34200  1.000 302.67000 ? 363 LYS B CD    1 
ATOM   6819 C  CE    . LYS B 2 363 ? 49.48300  43.81100  9.83700   1.000 300.36000 ? 363 LYS B CE    1 
ATOM   6820 N  NZ    . LYS B 2 363 ? 49.85900  43.48200  8.46000   1.000 292.02000 ? 363 LYS B NZ    1 
ATOM   6821 N  N     . GLN B 2 364 ? 53.17200  39.57000  11.00100  1.000 294.18000 ? 364 GLN B N     1 
ATOM   6822 C  CA    . GLN B 2 364 ? 54.21300  38.99200  10.15600  1.000 292.48000 ? 364 GLN B CA    1 
ATOM   6823 C  C     . GLN B 2 364 ? 54.55800  37.56500  10.57300  1.000 290.80000 ? 364 GLN B C     1 
ATOM   6824 O  O     . GLN B 2 364 ? 54.84600  36.71700  9.71600   1.000 290.75000 ? 364 GLN B O     1 
ATOM   6825 C  CB    . GLN B 2 364 ? 55.45400  39.89300  10.19900  1.000 297.06000 ? 364 GLN B CB    1 
ATOM   6826 C  CG    . GLN B 2 364 ? 56.74500  39.23100  9.77000   1.000 300.73000 ? 364 GLN B CG    1 
ATOM   6827 C  CD    . GLN B 2 364 ? 56.68400  38.66500  8.37500   1.000 287.51000 ? 364 GLN B CD    1 
ATOM   6828 O  OE1   . GLN B 2 364 ? 57.20100  37.59400  8.11500   1.000 295.76000 ? 364 GLN B OE1   1 
ATOM   6829 N  NE2   . GLN B 2 364 ? 56.04400  39.38600  7.46900   1.000 290.81000 ? 364 GLN B NE2   1 
ATOM   6830 N  N     . GLY B 2 365 ? 54.49900  37.27800  11.87900  1.000 292.21000 ? 365 GLY B N     1 
ATOM   6831 C  CA    . GLY B 2 365 ? 54.79100  35.93500  12.34600  1.000 289.55000 ? 365 GLY B CA    1 
ATOM   6832 C  C     . GLY B 2 365 ? 53.95900  34.88000  11.63100  1.000 290.33000 ? 365 GLY B C     1 
ATOM   6833 O  O     . GLY B 2 365 ? 54.49800  33.85600  11.18400  1.000 290.27000 ? 365 GLY B O     1 
ATOM   6834 N  N     . LYS B 2 366 ? 52.62700  35.11300  11.50500  1.000 291.62000 ? 366 LYS B N     1 
ATOM   6835 C  CA    . LYS B 2 366 ? 51.76600  34.14700  10.81700  1.000 293.15000 ? 366 LYS B CA    1 
ATOM   6836 C  C     . LYS B 2 366 ? 52.42100  33.62500  9.56300   1.000 297.97000 ? 366 LYS B C     1 
ATOM   6837 O  O     . LYS B 2 366 ? 52.24300  32.46000  9.20500   1.000 299.51000 ? 366 LYS B O     1 
ATOM   6838 C  CB    . LYS B 2 366 ? 50.42200  34.77400  10.45600  1.000 286.82000 ? 366 LYS B CB    1 
ATOM   6839 N  N     . ASN B 2 367 ? 53.21200  34.46000  8.90600   1.000 299.75000 ? 367 ASN B N     1 
ATOM   6840 C  CA    . ASN B 2 367 ? 53.84700  34.02600  7.67600   1.000 298.84000 ? 367 ASN B CA    1 
ATOM   6841 C  C     . ASN B 2 367 ? 54.93200  32.98900  7.93200   1.000 294.80000 ? 367 ASN B C     1 
ATOM   6842 O  O     . ASN B 2 367 ? 54.97600  31.95400  7.25700   1.000 301.45000 ? 367 ASN B O     1 
ATOM   6843 C  CB    . ASN B 2 367 ? 54.38500  35.23800  6.93500   1.000 308.49000 ? 367 ASN B CB    1 
ATOM   6844 C  CG    . ASN B 2 367 ? 53.26800  36.04900  6.28900   1.000 313.43000 ? 367 ASN B CG    1 
ATOM   6845 O  OD1   . ASN B 2 367 ? 52.11900  35.60900  6.22700   1.000 310.75000 ? 367 ASN B OD1   1 
ATOM   6846 N  ND2   . ASN B 2 367 ? 53.60700  37.23100  5.78200   1.000 317.79000 ? 367 ASN B ND2   1 
ATOM   6847 N  N     . TRP B 2 368 ? 55.75600  33.19100  8.94400   1.000 297.42000 ? 368 TRP B N     1 
ATOM   6848 C  CA    . TRP B 2 368 ? 56.91300  32.32700  9.11400   1.000 300.88000 ? 368 TRP B CA    1 
ATOM   6849 C  C     . TRP B 2 368 ? 56.55000  30.98300  9.74300   1.000 300.62000 ? 368 TRP B C     1 
ATOM   6850 O  O     . TRP B 2 368 ? 55.95400  30.94800  10.82200  1.000 300.19000 ? 368 TRP B O     1 
ATOM   6851 C  CB    . TRP B 2 368 ? 57.93700  33.08800  9.94400   1.000 306.82000 ? 368 TRP B CB    1 
ATOM   6852 C  CG    . TRP B 2 368 ? 58.42000  34.35200  9.19800   1.000 315.23000 ? 368 TRP B CG    1 
ATOM   6853 C  CD1   . TRP B 2 368 ? 57.97700  34.84600  7.98500   1.000 309.57000 ? 368 TRP B CD1   1 
ATOM   6854 C  CD2   . TRP B 2 368 ? 59.45200  35.24500  9.62500   1.000 321.00000 ? 368 TRP B CD2   1 
ATOM   6855 N  NE1   . TRP B 2 368 ? 58.66700  35.99300  7.65100   1.000 303.42000 ? 368 TRP B NE1   1 
ATOM   6856 C  CE2   . TRP B 2 368 ? 59.58500  36.25200  8.63100   1.000 311.67000 ? 368 TRP B CE2   1 
ATOM   6857 C  CE3   . TRP B 2 368 ? 60.28500  35.28600  10.75200  1.000 317.46000 ? 368 TRP B CE3   1 
ATOM   6858 C  CZ2   . TRP B 2 368 ? 60.49600  37.28700  8.74200   1.000 310.57000 ? 368 TRP B CZ2   1 
ATOM   6859 C  CZ3   . TRP B 2 368 ? 61.19000  36.30300  10.86300  1.000 315.11000 ? 368 TRP B CZ3   1 
ATOM   6860 C  CH2   . TRP B 2 368 ? 61.29600  37.29800  9.86000   1.000 318.90000 ? 368 TRP B CH2   1 
ATOM   6861 N  N     . TRP B 2 369 ? 56.90100  29.87700  9.06200   1.000 300.38000 ? 369 TRP B N     1 
ATOM   6862 C  CA    . TRP B 2 369 ? 56.73500  28.52600  9.61100   1.000 302.88000 ? 369 TRP B CA    1 
ATOM   6863 C  C     . TRP B 2 369 ? 58.10200  27.92800  9.95100   1.000 303.13000 ? 369 TRP B C     1 
ATOM   6864 O  O     . TRP B 2 369 ? 59.13500  28.52900  9.63800   1.000 301.18000 ? 369 TRP B O     1 
ATOM   6865 C  CB    . TRP B 2 369 ? 55.93900  27.61800  8.65900   1.000 298.33000 ? 369 TRP B CB    1 
ATOM   6866 C  CG    . TRP B 2 369 ? 54.50100  28.05600  8.41900   1.000 294.01000 ? 369 TRP B CG    1 
ATOM   6867 C  CD1   . TRP B 2 369 ? 53.79400  27.93900  7.25500   1.000 288.97000 ? 369 TRP B CD1   1 
ATOM   6868 C  CD2   . TRP B 2 369 ? 53.62400  28.70200  9.34800   1.000 309.47000 ? 369 TRP B CD2   1 
ATOM   6869 N  NE1   . TRP B 2 369 ? 52.53600  28.45900  7.40900   1.000 294.21000 ? 369 TRP B NE1   1 
ATOM   6870 C  CE2   . TRP B 2 369 ? 52.40900  28.93700  8.68500   1.000 304.60000 ? 369 TRP B CE2   1 
ATOM   6871 C  CE3   . TRP B 2 369 ? 53.74100  29.08900  10.68100  1.000 307.66000 ? 369 TRP B CE3   1 
ATOM   6872 C  CZ2   . TRP B 2 369 ? 51.32800  29.54900  9.30800   1.000 314.60000 ? 369 TRP B CZ2   1 
ATOM   6873 C  CZ3   . TRP B 2 369 ? 52.68100  29.70900  11.29100  1.000 308.93000 ? 369 TRP B CZ3   1 
ATOM   6874 C  CH2   . TRP B 2 369 ? 51.48300  29.92600  10.61100  1.000 307.61000 ? 369 TRP B CH2   1 
ATOM   6875 N  N     . ASN B 2 370 ? 58.10100  26.74500  10.61600  1.000 300.79000 ? 370 ASN B N     1 
ATOM   6876 C  CA    . ASN B 2 370 ? 59.26600  26.19900  11.34000  1.000 299.86000 ? 370 ASN B CA    1 
ATOM   6877 C  C     . ASN B 2 370 ? 60.49200  26.25700  10.46600  1.000 293.96000 ? 370 ASN B C     1 
ATOM   6878 O  O     . ASN B 2 370 ? 61.55800  26.68900  10.92000  1.000 291.50000 ? 370 ASN B O     1 
ATOM   6879 C  CB    . ASN B 2 370 ? 59.01000  24.74700  11.82700  1.000 300.01000 ? 370 ASN B CB    1 
ATOM   6880 C  CG    . ASN B 2 370 ? 60.25600  24.03400  12.52900  1.000 296.51000 ? 370 ASN B CG    1 
ATOM   6881 O  OD1   . ASN B 2 370 ? 60.20700  23.69300  13.73300  1.000 286.94000 ? 370 ASN B OD1   1 
ATOM   6882 N  ND2   . ASN B 2 370 ? 61.32900  23.78800  11.76800  1.000 299.26000 ? 370 ASN B ND2   1 
ATOM   6883 N  N     . ASP B 2 371 ? 60.34200  25.83500  9.21300   1.000 295.27000 ? 371 ASP B N     1 
ATOM   6884 C  CA    . ASP B 2 371 ? 61.44200  26.01800  8.28300   1.000 290.80000 ? 371 ASP B CA    1 
ATOM   6885 C  C     . ASP B 2 371 ? 61.94300  27.46300  8.29900   1.000 294.28000 ? 371 ASP B C     1 
ATOM   6886 O  O     . ASP B 2 371 ? 63.15400  27.70700  8.40700   1.000 298.10000 ? 371 ASP B O     1 
ATOM   6887 C  CB    . ASP B 2 371 ? 61.01600  25.61900  6.88100   1.000 283.58000 ? 371 ASP B CB    1 
ATOM   6888 C  CG    . ASP B 2 371 ? 59.80100  26.38300  6.41300   1.000 288.90000 ? 371 ASP B CG    1 
ATOM   6889 O  OD1   . ASP B 2 371 ? 59.17000  27.05800  7.26300   1.000 293.76000 ? 371 ASP B OD1   1 
ATOM   6890 O  OD2   . ASP B 2 371 ? 59.48100  26.31300  5.20500   1.000 289.63000 ? 371 ASP B OD2   1 
ATOM   6891 N  N     . LYS B 2 372 ? 61.02800  28.44100  8.24300   1.000 296.86000 ? 372 LYS B N     1 
ATOM   6892 C  CA    . LYS B 2 372 ? 61.47100  29.82400  8.05200   1.000 296.04000 ? 372 LYS B CA    1 
ATOM   6893 C  C     . LYS B 2 372 ? 62.14800  30.39700  9.28800   1.000 291.91000 ? 372 LYS B C     1 
ATOM   6894 O  O     . LYS B 2 372 ? 63.22900  30.99200  9.17900   1.000 291.59000 ? 372 LYS B O     1 
ATOM   6895 C  CB    . LYS B 2 372 ? 60.30300  30.71800  7.63800   1.000 300.87000 ? 372 LYS B CB    1 
ATOM   6896 C  CG    . LYS B 2 372 ? 60.15800  30.94700  6.13800   1.000 296.63000 ? 372 LYS B CG    1 
ATOM   6897 C  CD    . LYS B 2 372 ? 59.11000  30.01200  5.55200   1.000 293.89000 ? 372 LYS B CD    1 
ATOM   6898 C  CE    . LYS B 2 372 ? 58.59000  30.51300  4.21900   1.000 304.99000 ? 372 LYS B CE    1 
ATOM   6899 N  NZ    . LYS B 2 372 ? 57.84200  31.76900  4.41800   1.000 304.39000 ? 372 LYS B NZ    1 
ATOM   6900 N  N     . TRP B 2 373 ? 61.53300  30.24300  10.46100  1.000 290.50000 ? 373 TRP B N     1 
ATOM   6901 C  CA    . TRP B 2 373 ? 62.15400  30.77000  11.66600  1.000 288.73000 ? 373 TRP B CA    1 
ATOM   6902 C  C     . TRP B 2 373 ? 63.55600  30.21000  11.86300  1.000 295.64000 ? 373 TRP B C     1 
ATOM   6903 O  O     . TRP B 2 373 ? 64.45200  30.92800  12.32000  1.000 297.68000 ? 373 TRP B O     1 
ATOM   6904 C  CB    . TRP B 2 373 ? 61.27700  30.45900  12.88200  1.000 294.66000 ? 373 TRP B CB    1 
ATOM   6905 C  CG    . TRP B 2 373 ? 60.53700  31.63900  13.42000  1.000 296.92000 ? 373 TRP B CG    1 
ATOM   6906 C  CD1   . TRP B 2 373 ? 59.96100  32.63700  12.70900  1.000 294.94000 ? 373 TRP B CD1   1 
ATOM   6907 C  CD2   . TRP B 2 373 ? 60.30400  31.94400  14.80200  1.000 306.17000 ? 373 TRP B CD2   1 
ATOM   6908 N  NE1   . TRP B 2 373 ? 59.37800  33.54800  13.55000  1.000 295.79000 ? 373 TRP B NE1   1 
ATOM   6909 C  CE2   . TRP B 2 373 ? 59.57400  33.14400  14.84200  1.000 306.35000 ? 373 TRP B CE2   1 
ATOM   6910 C  CE3   . TRP B 2 373 ? 60.65100  31.31900  16.01300  1.000 305.50000 ? 373 TRP B CE3   1 
ATOM   6911 C  CZ2   . TRP B 2 373 ? 59.17400  33.73000  16.03400  1.000 317.00000 ? 373 TRP B CZ2   1 
ATOM   6912 C  CZ3   . TRP B 2 373 ? 60.24700  31.89400  17.20100  1.000 306.33000 ? 373 TRP B CZ3   1 
ATOM   6913 C  CH2   . TRP B 2 373 ? 59.52000  33.09300  17.20600  1.000 318.59000 ? 373 TRP B CH2   1 
ATOM   6914 N  N     . ARG B 2 374 ? 63.76400  28.93400  11.52500  1.000 295.13000 ? 374 ARG B N     1 
ATOM   6915 C  CA    . ARG B 2 374 ? 65.07100  28.31000  11.74600  1.000 299.29000 ? 374 ARG B CA    1 
ATOM   6916 C  C     . ARG B 2 374 ? 66.15300  28.91100  10.85500  1.000 298.75000 ? 374 ARG B C     1 
ATOM   6917 O  O     . ARG B 2 374 ? 67.19800  29.37000  11.34400  1.000 296.11000 ? 374 ARG B O     1 
ATOM   6918 C  CB    . ARG B 2 374 ? 64.99100  26.80400  11.52000  1.000 301.03000 ? 374 ARG B CB    1 
ATOM   6919 C  CG    . ARG B 2 374 ? 66.36800  26.13100  11.37200  1.000 304.29000 ? 374 ARG B CG    1 
ATOM   6920 C  CD    . ARG B 2 374 ? 66.35700  24.71200  10.77100  1.000 302.44000 ? 374 ARG B CD    1 
ATOM   6921 N  NE    . ARG B 2 374 ? 67.32400  24.64500  9.67400   1.000 298.91000 ? 374 ARG B NE    1 
ATOM   6922 C  CZ    . ARG B 2 374 ? 67.00300  24.64800  8.38300   1.000 308.80000 ? 374 ARG B CZ    1 
ATOM   6923 N  NH1   . ARG B 2 374 ? 65.73000  24.67100  8.00100   1.000 305.93000 ? 374 ARG B NH1   1 
ATOM   6924 N  NH2   . ARG B 2 374 ? 67.96000  24.61600  7.47100   1.000 311.96000 ? 374 ARG B NH2   1 
ATOM   6925 N  N     . GLU B 2 375 ? 65.92400  28.91100  9.54600   1.000 301.23000 ? 375 GLU B N     1 
ATOM   6926 C  CA    . GLU B 2 375 ? 66.94400  29.39300  8.63000   1.000 295.45000 ? 375 GLU B CA    1 
ATOM   6927 C  C     . GLU B 2 375 ? 67.38900  30.79100  8.98800   1.000 291.58000 ? 375 GLU B C     1 
ATOM   6928 O  O     . GLU B 2 375 ? 68.58500  31.03000  9.21600   1.000 294.22000 ? 375 GLU B O     1 
ATOM   6929 C  CB    . GLU B 2 375 ? 66.41000  29.36400  7.20800   1.000 300.53000 ? 375 GLU B CB    1 
ATOM   6930 C  CG    . GLU B 2 375 ? 65.05400  29.99800  7.05200   1.000 298.18000 ? 375 GLU B CG    1 
ATOM   6931 C  CD    . GLU B 2 375 ? 64.49800  29.75200  5.68800   1.000 316.44000 ? 375 GLU B CD    1 
ATOM   6932 O  OE1   . GLU B 2 375 ? 64.65300  28.59800  5.20300   1.000 329.62000 ? 375 GLU B OE1   1 
ATOM   6933 O  OE2   . GLU B 2 375 ? 63.94500  30.72300  5.10600   1.000 325.41000 ? 375 GLU B OE2   1 
ATOM   6934 N  N     . LYS B 2 376 ? 66.43300  31.71500  9.07300   1.000 284.58000 ? 376 LYS B N     1 
ATOM   6935 C  CA    . LYS B 2 376 ? 66.77000  33.08700  9.38400   1.000 283.53000 ? 376 LYS B CA    1 
ATOM   6936 C  C     . LYS B 2 376 ? 67.64500  33.18200  10.62900  1.000 290.28000 ? 376 LYS B C     1 
ATOM   6937 O  O     . LYS B 2 376 ? 68.70800  33.81000  10.59000  1.000 291.31000 ? 376 LYS B O     1 
ATOM   6938 C  CB    . LYS B 2 376 ? 65.49200  33.89600  9.54400   1.000 280.85000 ? 376 LYS B CB    1 
ATOM   6939 C  CG    . LYS B 2 376 ? 64.47100  33.59500  8.48000   1.000 282.22000 ? 376 LYS B CG    1 
ATOM   6940 C  CD    . LYS B 2 376 ? 64.15300  34.81200  7.68000   1.000 286.24000 ? 376 LYS B CD    1 
ATOM   6941 C  CE    . LYS B 2 376 ? 62.88400  34.58700  6.89300   1.000 291.69000 ? 376 LYS B CE    1 
ATOM   6942 N  NZ    . LYS B 2 376 ? 63.16800  34.16600  5.50600   1.000 289.78000 ? 376 LYS B NZ    1 
ATOM   6943 N  N     . LEU B 2 377 ? 67.23700  32.54400  11.73600  1.000 291.88000 ? 377 LEU B N     1 
ATOM   6944 C  CA    . LEU B 2 377 ? 68.08300  32.51900  12.93700  1.000 291.15000 ? 377 LEU B CA    1 
ATOM   6945 C  C     . LEU B 2 377 ? 69.46800  31.97000  12.62400  1.000 292.74000 ? 377 LEU B C     1 
ATOM   6946 O  O     . LEU B 2 377 ? 70.46200  32.71100  12.69600  1.000 295.30000 ? 377 LEU B O     1 
ATOM   6947 C  CB    . LEU B 2 377 ? 67.42100  31.71000  14.06800  1.000 289.19000 ? 377 LEU B CB    1 
ATOM   6948 C  CG    . LEU B 2 377 ? 67.98300  31.52300  15.50900  1.000 290.73000 ? 377 LEU B CG    1 
ATOM   6949 C  CD1   . LEU B 2 377 ? 67.76900  32.71200  16.47500  1.000 292.54000 ? 377 LEU B CD1   1 
ATOM   6950 C  CD2   . LEU B 2 377 ? 67.50500  30.25300  16.19900  1.000 286.06000 ? 377 LEU B CD2   1 
ATOM   6951 N  N     . LEU B 2 378 ? 69.54600  30.69000  12.22300  1.000 294.98000 ? 378 LEU B N     1 
ATOM   6952 C  CA    . LEU B 2 378 ? 70.83500  30.09400  11.88800  1.000 301.46000 ? 378 LEU B CA    1 
ATOM   6953 C  C     . LEU B 2 378 ? 71.68600  31.05100  11.08500  1.000 304.53000 ? 378 LEU B C     1 
ATOM   6954 O  O     . LEU B 2 378 ? 72.81400  31.37100  11.48400  1.000 308.23000 ? 378 LEU B O     1 
ATOM   6955 C  CB    . LEU B 2 378 ? 70.63700  28.79700  11.10700  1.000 297.25000 ? 378 LEU B CB    1 
ATOM   6956 C  CG    . LEU B 2 378 ? 70.62100  27.65300  12.11000  1.000 301.96000 ? 378 LEU B CG    1 
ATOM   6957 C  CD1   . LEU B 2 378 ? 69.26900  27.54400  12.80300  1.000 300.04000 ? 378 LEU B CD1   1 
ATOM   6958 C  CD2   . LEU B 2 378 ? 71.05000  26.36500  11.44700  1.000 301.86000 ? 378 LEU B CD2   1 
ATOM   6959 N  N     . ALA B 2 379 ? 71.12400  31.57100  9.99200   1.000 303.50000 ? 379 ALA B N     1 
ATOM   6960 C  CA    . ALA B 2 379 ? 71.83900  32.53000  9.16200   1.000 303.73000 ? 379 ALA B CA    1 
ATOM   6961 C  C     . ALA B 2 379 ? 72.23200  33.77900  9.94100   1.000 300.48000 ? 379 ALA B C     1 
ATOM   6962 O  O     . ALA B 2 379 ? 73.38200  34.23000  9.85200   1.000 303.86000 ? 379 ALA B O     1 
ATOM   6963 C  CB    . ALA B 2 379 ? 70.97200  32.89900  7.96100   1.000 302.60000 ? 379 ALA B CB    1 
ATOM   6964 N  N     . PHE B 2 380 ? 71.29000  34.37700  10.68300  1.000 297.20000 ? 380 PHE B N     1 
ATOM   6965 C  CA    . PHE B 2 380 ? 71.68700  35.52000  11.50000  1.000 292.83000 ? 380 PHE B CA    1 
ATOM   6966 C  C     . PHE B 2 380 ? 72.92700  35.17500  12.31800  1.000 297.01000 ? 380 PHE B C     1 
ATOM   6967 O  O     . PHE B 2 380 ? 73.91800  35.90900  12.29600  1.000 296.56000 ? 380 PHE B O     1 
ATOM   6968 C  CB    . PHE B 2 380 ? 70.53900  36.01100  12.38700  1.000 292.00000 ? 380 PHE B CB    1 
ATOM   6969 C  CG    . PHE B 2 380 ? 70.62200  37.50200  12.71800  1.000 288.93000 ? 380 PHE B CG    1 
ATOM   6970 C  CD1   . PHE B 2 380 ? 71.65400  37.99700  13.47700  1.000 290.55000 ? 380 PHE B CD1   1 
ATOM   6971 C  CD2   . PHE B 2 380 ? 69.65000  38.39200  12.30100  1.000 288.67000 ? 380 PHE B CD2   1 
ATOM   6972 C  CE1   . PHE B 2 380 ? 71.71800  39.33900  13.78400  1.000 291.05000 ? 380 PHE B CE1   1 
ATOM   6973 C  CE2   . PHE B 2 380 ? 69.70600  39.72400  12.62400  1.000 291.08000 ? 380 PHE B CE2   1 
ATOM   6974 C  CZ    . PHE B 2 380 ? 70.74900  40.19800  13.35400  1.000 294.57000 ? 380 PHE B CZ    1 
ATOM   6975 N  N     . ILE B 2 381 ? 72.94700  34.00700  12.95300  1.000 296.68000 ? 381 ILE B N     1 
ATOM   6976 C  CA    . ILE B 2 381 ? 74.14300  33.65000  13.71700  1.000 301.11000 ? 381 ILE B CA    1 
ATOM   6977 C  C     . ILE B 2 381 ? 75.28000  33.28800  12.77200  1.000 297.70000 ? 381 ILE B C     1 
ATOM   6978 O  O     . ILE B 2 381 ? 76.43800  33.67600  12.99300  1.000 299.24000 ? 381 ILE B O     1 
ATOM   6979 C  CB    . ILE B 2 381 ? 73.84100  32.53000  14.73800  1.000 309.61000 ? 381 ILE B CB    1 
ATOM   6980 C  CG1   . ILE B 2 381 ? 72.64300  32.93900  15.63100  1.000 311.62000 ? 381 ILE B CG1   1 
ATOM   6981 C  CG2   . ILE B 2 381 ? 75.10300  32.18200  15.62400  1.000 316.61000 ? 381 ILE B CG2   1 
ATOM   6982 C  CD1   . ILE B 2 381 ? 73.05700  33.79600  16.94300  1.000 306.83000 ? 381 ILE B CD1   1 
ATOM   6983 N  N     . ARG B 2 382 ? 74.97200  32.60400  11.67000  1.000 298.25000 ? 382 ARG B N     1 
ATOM   6984 C  CA    . ARG B 2 382 ? 75.99400  32.53400  10.63800  1.000 300.22000 ? 382 ARG B CA    1 
ATOM   6985 C  C     . ARG B 2 382 ? 76.46000  33.93300  10.27400  1.000 303.33000 ? 382 ARG B C     1 
ATOM   6986 O  O     . ARG B 2 382 ? 77.66500  34.16100  10.10300  1.000 312.81000 ? 382 ARG B O     1 
ATOM   6987 C  CB    . ARG B 2 382 ? 75.48900  31.78800  9.40200   1.000 302.82000 ? 382 ARG B CB    1 
ATOM   6988 C  CG    . ARG B 2 382 ? 75.20000  30.33400  9.62000   1.000 301.70000 ? 382 ARG B CG    1 
ATOM   6989 C  CD    . ARG B 2 382 ? 74.25300  29.89400  8.53800   1.000 301.05000 ? 382 ARG B CD    1 
ATOM   6990 N  NE    . ARG B 2 382 ? 73.56100  28.65200  8.83900   1.000 311.41000 ? 382 ARG B NE    1 
ATOM   6991 C  CZ    . ARG B 2 382 ? 72.78400  28.03900  7.96100   1.000 316.12000 ? 382 ARG B CZ    1 
ATOM   6992 N  NH1   . ARG B 2 382 ? 72.63400  28.57200  6.76200   1.000 316.34000 ? 382 ARG B NH1   1 
ATOM   6993 N  NH2   . ARG B 2 382 ? 72.16700  26.90900  8.27500   1.000 314.56000 ? 382 ARG B NH2   1 
ATOM   6994 N  N     . PHE B 2 383 ? 75.52100  34.89500  10.23600  1.000 303.33000 ? 383 PHE B N     1 
ATOM   6995 C  CA    . PHE B 2 383 ? 75.84300  36.25400  9.80600   1.000 302.35000 ? 383 PHE B CA    1 
ATOM   6996 C  C     . PHE B 2 383 ? 76.93100  36.86200  10.67500  1.000 303.06000 ? 383 PHE B C     1 
ATOM   6997 O  O     . PHE B 2 383 ? 77.93800  37.40100  10.17900  1.000 304.03000 ? 383 PHE B O     1 
ATOM   6998 C  CB    . PHE B 2 383 ? 74.62000  37.15200  9.84200   1.000 298.43000 ? 383 PHE B CB    1 
ATOM   6999 C  CG    . PHE B 2 383 ? 74.96900  38.63500  9.80300   1.000 298.08000 ? 383 PHE B CG    1 
ATOM   7000 C  CD1   . PHE B 2 383 ? 75.27000  39.35400  10.95800  1.000 301.94000 ? 383 PHE B CD1   1 
ATOM   7001 C  CD2   . PHE B 2 383 ? 74.95300  39.32000  8.61400   1.000 299.61000 ? 383 PHE B CD2   1 
ATOM   7002 C  CE1   . PHE B 2 383 ? 75.58900  40.69900  10.90300  1.000 304.76000 ? 383 PHE B CE1   1 
ATOM   7003 C  CE2   . PHE B 2 383 ? 75.25100  40.66100  8.55100   1.000 303.00000 ? 383 PHE B CE2   1 
ATOM   7004 C  CZ    . PHE B 2 383 ? 75.57100  41.36200  9.70200   1.000 305.20000 ? 383 PHE B CZ    1 
ATOM   7005 N  N     . LEU B 2 384 ? 76.68400  36.88000  11.98000  1.000 309.82000 ? 384 LEU B N     1 
ATOM   7006 C  CA    . LEU B 2 384 ? 77.56900  37.60000  12.87800  1.000 314.62000 ? 384 LEU B CA    1 
ATOM   7007 C  C     . LEU B 2 384 ? 78.95400  36.99600  12.86300  1.000 314.32000 ? 384 LEU B C     1 
ATOM   7008 O  O     . LEU B 2 384 ? 79.93900  37.73900  12.94000  1.000 309.79000 ? 384 LEU B O     1 
ATOM   7009 C  CB    . LEU B 2 384 ? 76.98500  37.58300  14.30000  1.000 326.32000 ? 384 LEU B CB    1 
ATOM   7010 C  CG    . LEU B 2 384 ? 75.49500  37.93800  14.50600  1.000 326.41000 ? 384 LEU B CG    1 
ATOM   7011 C  CD1   . LEU B 2 384 ? 74.96000  37.53900  15.89300  1.000 329.53000 ? 384 LEU B CD1   1 
ATOM   7012 C  CD2   . LEU B 2 384 ? 75.26100  39.41400  14.30300  1.000 329.06000 ? 384 LEU B CD2   1 
ATOM   7013 N  N     . SER B 2 385 ? 79.03300  35.66300  12.68600  1.000 317.85000 ? 385 SER B N     1 
ATOM   7014 C  CA    . SER B 2 385 ? 80.24600  34.90100  12.97000  1.000 317.06000 ? 385 SER B CA    1 
ATOM   7015 C  C     . SER B 2 385 ? 81.46400  35.59600  12.39800  1.000 318.99000 ? 385 SER B C     1 
ATOM   7016 O  O     . SER B 2 385 ? 81.43200  36.11600  11.28000  1.000 319.37000 ? 385 SER B O     1 
ATOM   7017 C  CB    . SER B 2 385 ? 80.15700  33.48300  12.40100  1.000 313.02000 ? 385 SER B CB    1 
ATOM   7018 O  OG    . SER B 2 385 ? 78.85300  33.16500  11.94600  1.000 308.93000 ? 385 SER B OG    1 
ATOM   7019 N  N     . ASP B 2 386 ? 82.51700  35.65900  13.20000  1.000 319.86000 ? 386 ASP B N     1 
ATOM   7020 C  CA    . ASP B 2 386 ? 83.73200  36.31000  12.74900  1.000 320.68000 ? 386 ASP B CA    1 
ATOM   7021 C  C     . ASP B 2 386 ? 84.79100  35.32100  12.32000  1.000 322.54000 ? 386 ASP B C     1 
ATOM   7022 O  O     . ASP B 2 386 ? 85.92300  35.73800  12.02600  1.000 328.05000 ? 386 ASP B O     1 
ATOM   7023 C  CB    . ASP B 2 386 ? 84.29500  37.23500  13.83200  1.000 327.62000 ? 386 ASP B CB    1 
ATOM   7024 C  CG    . ASP B 2 386 ? 83.29200  38.31000  14.25200  1.000 326.33000 ? 386 ASP B CG    1 
ATOM   7025 O  OD1   . ASP B 2 386 ? 82.09900  37.99600  14.26800  1.000 318.08000 ? 386 ASP B OD1   1 
ATOM   7026 O  OD2   . ASP B 2 386 ? 83.67400  39.47000  14.54600  1.000 333.48000 ? 386 ASP B OD2   1 
ATOM   7027 N  N     . ASP B 2 387 ? 84.44200  34.03700  12.24600  1.000 320.61000 ? 387 ASP B N     1 
ATOM   7028 C  CA    . ASP B 2 387 ? 85.23100  33.07600  11.49400  1.000 321.22000 ? 387 ASP B CA    1 
ATOM   7029 C  C     . ASP B 2 387 ? 84.37300  31.84900  11.21800  1.000 315.47000 ? 387 ASP B C     1 
ATOM   7030 O  O     . ASP B 2 387 ? 83.16400  31.81900  11.48600  1.000 312.92000 ? 387 ASP B O     1 
ATOM   7031 C  CB    . ASP B 2 387 ? 86.51200  32.68500  12.23100  1.000 325.33000 ? 387 ASP B CB    1 
ATOM   7032 C  CG    . ASP B 2 387 ? 86.26200  31.83300  13.45900  1.000 331.19000 ? 387 ASP B CG    1 
ATOM   7033 O  OD1   . ASP B 2 387 ? 85.65400  30.74100  13.32000  1.000 333.80000 ? 387 ASP B OD1   1 
ATOM   7034 O  OD2   . ASP B 2 387 ? 86.70000  32.23000  14.54200  1.000 340.42000 ? 387 ASP B OD2   1 
ATOM   7035 N  N     . GLN B 2 388 ? 85.05100  30.79300  10.76800  1.000 312.45000 ? 388 GLN B N     1 
ATOM   7036 C  CA    . GLN B 2 388 ? 84.36300  29.64400  10.19000  1.000 309.68000 ? 388 GLN B CA    1 
ATOM   7037 C  C     . GLN B 2 388 ? 83.48300  28.91200  11.19800  1.000 309.35000 ? 388 GLN B C     1 
ATOM   7038 O  O     . GLN B 2 388 ? 82.40300  28.43000  10.84000  1.000 307.36000 ? 388 GLN B O     1 
ATOM   7039 C  CB    . GLN B 2 388 ? 85.37900  28.68600  9.60600   1.000 310.59000 ? 388 GLN B CB    1 
ATOM   7040 C  CG    . GLN B 2 388 ? 86.64200  29.36400  9.15900   1.000 318.27000 ? 388 GLN B CG    1 
ATOM   7041 C  CD    . GLN B 2 388 ? 87.81000  28.44300  9.29600   1.000 322.34000 ? 388 GLN B CD    1 
ATOM   7042 O  OE1   . GLN B 2 388 ? 87.69500  27.24000  9.06100   1.000 315.48000 ? 388 GLN B OE1   1 
ATOM   7043 N  NE2   . GLN B 2 388 ? 88.94300  28.98900  9.69800   1.000 321.76000 ? 388 GLN B NE2   1 
ATOM   7044 N  N     . ASN B 2 389 ? 83.90900  28.81100  12.45900  1.000 326.14000 ? 389 ASN B N     1 
ATOM   7045 C  CA    . ASN B 2 389 ? 83.21800  27.91100  13.38700  1.000 327.39000 ? 389 ASN B CA    1 
ATOM   7046 C  C     . ASN B 2 389 ? 82.53300  28.60300  14.56400  1.000 325.61000 ? 389 ASN B C     1 
ATOM   7047 O  O     . ASN B 2 389 ? 81.80300  27.93300  15.30500  1.000 319.24000 ? 389 ASN B O     1 
ATOM   7048 C  CB    . ASN B 2 389 ? 84.18400  26.83300  13.93700  1.000 333.02000 ? 389 ASN B CB    1 
ATOM   7049 C  CG    . ASN B 2 389 ? 85.64300  27.27500  13.97700  1.000 341.98000 ? 389 ASN B CG    1 
ATOM   7050 O  OD1   . ASN B 2 389 ? 86.08600  28.08700  13.15700  1.000 337.81000 ? 389 ASN B OD1   1 
ATOM   7051 N  ND2   . ASN B 2 389 ? 86.40100  26.71700  14.92200  1.000 353.10000 ? 389 ASN B ND2   1 
ATOM   7052 N  N     . ALA B 2 390 ? 82.71300  29.91500  14.74000  1.000 325.43000 ? 390 ALA B N     1 
ATOM   7053 C  CA    . ALA B 2 390 ? 82.17900  30.55500  15.93600  1.000 323.24000 ? 390 ALA B CA    1 
ATOM   7054 C  C     . ALA B 2 390 ? 82.11700  32.07400  15.84500  1.000 321.09000 ? 390 ALA B C     1 
ATOM   7055 O  O     . ALA B 2 390 ? 82.57100  32.69100  14.87700  1.000 318.31000 ? 390 ALA B O     1 
ATOM   7056 C  CB    . ALA B 2 390 ? 82.98800  30.13500  17.16400  1.000 324.85000 ? 390 ALA B CB    1 
ATOM   7057 N  N     . ILE B 2 391 ? 81.50600  32.65600  16.90100  1.000 317.84000 ? 391 ILE B N     1 
ATOM   7058 C  CA    . ILE B 2 391 ? 81.58600  34.08400  17.17500  1.000 315.79000 ? 391 ILE B CA    1 
ATOM   7059 C  C     . ILE B 2 391 ? 82.72200  34.36600  18.15600  1.000 318.59000 ? 391 ILE B C     1 
ATOM   7060 O  O     . ILE B 2 391 ? 83.09900  33.52000  18.98900  1.000 316.99000 ? 391 ILE B O     1 
ATOM   7061 C  CB    . ILE B 2 391 ? 80.26100  34.60400  17.74400  1.000 313.85000 ? 391 ILE B CB    1 
ATOM   7062 C  CG1   . ILE B 2 391 ? 79.09400  34.23700  16.85500  1.000 320.59000 ? 391 ILE B CG1   1 
ATOM   7063 C  CG2   . ILE B 2 391 ? 80.31200  36.11200  17.88700  1.000 312.23000 ? 391 ILE B CG2   1 
ATOM   7064 C  CD1   . ILE B 2 391 ? 77.78800  34.94300  17.18700  1.000 322.46000 ? 391 ILE B CD1   1 
ATOM   7065 N  N     . TYR B 2 392 ? 83.27000  35.58100  18.05400  1.000 317.14000 ? 392 TYR B N     1 
ATOM   7066 C  CA    . TYR B 2 392 ? 84.13100  36.17000  19.07400  1.000 317.66000 ? 392 TYR B CA    1 
ATOM   7067 C  C     . TYR B 2 392 ? 83.28300  37.10000  19.94600  1.000 324.53000 ? 392 TYR B C     1 
ATOM   7068 O  O     . TYR B 2 392 ? 82.45900  37.85500  19.43200  1.000 325.53000 ? 392 TYR B O     1 
ATOM   7069 C  CB    . TYR B 2 392 ? 85.27700  36.96400  18.45000  1.000 320.15000 ? 392 TYR B CB    1 
ATOM   7070 C  CG    . TYR B 2 392 ? 86.26000  36.12400  17.66000  1.000 325.76000 ? 392 TYR B CG    1 
ATOM   7071 C  CD1   . TYR B 2 392 ? 87.18300  36.69400  16.77200  1.000 328.37000 ? 392 TYR B CD1   1 
ATOM   7072 C  CD2   . TYR B 2 392 ? 86.26300  34.75100  17.80100  1.000 326.07000 ? 392 TYR B CD2   1 
ATOM   7073 C  CE1   . TYR B 2 392 ? 88.08600  35.89700  16.04300  1.000 329.24000 ? 392 TYR B CE1   1 
ATOM   7074 C  CE2   . TYR B 2 392 ? 87.14200  33.95500  17.09700  1.000 331.42000 ? 392 TYR B CE2   1 
ATOM   7075 C  CZ    . TYR B 2 392 ? 88.04500  34.51200  16.22300  1.000 331.47000 ? 392 TYR B CZ    1 
ATOM   7076 O  OH    . TYR B 2 392 ? 88.90100  33.67300  15.54300  1.000 334.16000 ? 392 TYR B OH    1 
ATOM   7077 N  N     . LEU B 2 393 ? 83.47400  37.06000  21.26200  1.000 334.75000 ? 393 LEU B N     1 
ATOM   7078 C  CA    . LEU B 2 393 ? 83.07600  38.13900  22.16300  1.000 332.42000 ? 393 LEU B CA    1 
ATOM   7079 C  C     . LEU B 2 393 ? 84.31000  38.54600  22.94300  1.000 334.69000 ? 393 LEU B C     1 
ATOM   7080 O  O     . LEU B 2 393 ? 85.07900  37.70200  23.45600  1.000 340.34000 ? 393 LEU B O     1 
ATOM   7081 C  CB    . LEU B 2 393 ? 81.99700  37.75500  23.16200  1.000 326.65000 ? 393 LEU B CB    1 
ATOM   7082 C  CG    . LEU B 2 393 ? 80.85100  36.83600  22.78900  1.000 328.84000 ? 393 LEU B CG    1 
ATOM   7083 C  CD1   . LEU B 2 393 ? 80.89200  35.30500  23.22600  1.000 339.04000 ? 393 LEU B CD1   1 
ATOM   7084 C  CD2   . LEU B 2 393 ? 79.62300  37.43500  23.39900  1.000 322.37000 ? 393 LEU B CD2   1 
ATOM   7085 N  N     . ASN B 2 394 ? 84.46000  39.82700  23.06700  1.000 332.99000 ? 394 ASN B N     1 
ATOM   7086 C  CA    . ASN B 2 394 ? 85.69600  40.42500  23.51400  1.000 337.95000 ? 394 ASN B CA    1 
ATOM   7087 C  C     . ASN B 2 394 ? 85.49500  40.85200  24.95200  1.000 346.76000 ? 394 ASN B C     1 
ATOM   7088 O  O     . ASN B 2 394 ? 84.86300  41.87300  25.21500  1.000 346.48000 ? 394 ASN B O     1 
ATOM   7089 C  CB    . ASN B 2 394 ? 86.05700  41.54900  22.56200  1.000 343.64000 ? 394 ASN B CB    1 
ATOM   7090 C  CG    . ASN B 2 394 ? 86.63600  40.99300  21.29700  1.000 356.93000 ? 394 ASN B CG    1 
ATOM   7091 O  OD1   . ASN B 2 394 ? 87.29600  39.95500  21.35600  1.000 354.57000 ? 394 ASN B OD1   1 
ATOM   7092 N  ND2   . ASN B 2 394 ? 86.42000  41.65000  20.16200  1.000 362.97000 ? 394 ASN B ND2   1 
ATOM   7093 N  N     . VAL B 2 395 ? 85.90200  39.97000  25.87700  1.000 356.61000 ? 395 VAL B N     1 
ATOM   7094 C  CA    . VAL B 2 395 ? 85.99800  40.32900  27.29000  1.000 365.24000 ? 395 VAL B CA    1 
ATOM   7095 C  C     . VAL B 2 395 ? 87.21900  41.20900  27.51100  1.000 363.71000 ? 395 VAL B C     1 
ATOM   7096 O  O     . VAL B 2 395 ? 87.27000  42.01200  28.45100  1.000 363.23000 ? 395 VAL B O     1 
ATOM   7097 C  CB    . VAL B 2 395 ? 86.02900  39.06300  28.17900  1.000 360.14000 ? 395 VAL B CB    1 
ATOM   7098 C  CG1   . VAL B 2 395 ? 84.60600  38.54100  28.44900  1.000 357.50000 ? 395 VAL B CG1   1 
ATOM   7099 C  CG2   . VAL B 2 395 ? 86.95400  37.97500  27.58400  1.000 356.52000 ? 395 VAL B CG2   1 
ATOM   7100 N  N     . GLY B 2 396 ? 88.21400  41.07200  26.64300  1.000 354.65000 ? 396 GLY B N     1 
ATOM   7101 C  CA    . GLY B 2 396 ? 89.47100  41.77500  26.77500  1.000 353.24000 ? 396 GLY B CA    1 
ATOM   7102 C  C     . GLY B 2 396 ? 90.34600  41.50800  25.57600  1.000 337.45000 ? 396 GLY B C     1 
ATOM   7103 O  O     . GLY B 2 396 ? 89.99000  40.78300  24.64800  1.000 337.78000 ? 396 GLY B O     1 
ATOM   7104 N  N     . SER B 2 397 ? 91.52100  42.11500  25.62200  1.000 325.18000 ? 397 SER B N     1 
ATOM   7105 C  CA    . SER B 2 397 ? 92.42200  42.07600  24.47900  1.000 334.40000 ? 397 SER B CA    1 
ATOM   7106 C  C     . SER B 2 397 ? 92.88700  40.65800  24.18900  1.000 325.57000 ? 397 SER B C     1 
ATOM   7107 O  O     . SER B 2 397 ? 92.67000  40.14600  23.08800  1.000 320.46000 ? 397 SER B O     1 
ATOM   7108 C  CB    . SER B 2 397 ? 93.61200  42.99200  24.70900  1.000 338.87000 ? 397 SER B CB    1 
ATOM   7109 O  OG    . SER B 2 397 ? 94.58300  42.39900  25.54900  1.000 331.88000 ? 397 SER B OG    1 
ATOM   7110 N  N     . GLU B 2 398 ? 93.51000  39.99800  25.16800  1.000 341.62000 ? 398 GLU B N     1 
ATOM   7111 C  CA    . GLU B 2 398 ? 93.99400  38.63100  25.00600  1.000 347.52000 ? 398 GLU B CA    1 
ATOM   7112 C  C     . GLU B 2 398 ? 92.95300  37.58000  25.35900  1.000 347.21000 ? 398 GLU B C     1 
ATOM   7113 O  O     . GLU B 2 398 ? 93.18100  36.39000  25.11100  1.000 342.97000 ? 398 GLU B O     1 
ATOM   7114 C  CB    . GLU B 2 398 ? 95.24900  38.38400  25.86300  1.000 355.93000 ? 398 GLU B CB    1 
ATOM   7115 C  CG    . GLU B 2 398 ? 96.54300  38.94400  25.29000  1.000 357.50000 ? 398 GLU B CG    1 
ATOM   7116 C  CD    . GLU B 2 398 ? 97.61000  37.87500  25.05900  1.000 359.66000 ? 398 GLU B CD    1 
ATOM   7117 O  OE1   . GLU B 2 398 ? 97.25900  36.68300  24.90500  1.000 355.70000 ? 398 GLU B OE1   1 
ATOM   7118 O  OE2   . GLU B 2 398 ? 98.80700  38.23100  25.03400  1.000 369.38000 ? 398 GLU B OE2   1 
ATOM   7119 N  N     . GLU B 2 399 ? 91.83100  37.96100  25.95100  1.000 354.69000 ? 399 GLU B N     1 
ATOM   7120 C  CA    . GLU B 2 399 ? 90.85600  36.96400  26.36100  1.000 352.49000 ? 399 GLU B CA    1 
ATOM   7121 C  C     . GLU B 2 399 ? 89.61200  37.11600  25.50400  1.000 339.32000 ? 399 GLU B C     1 
ATOM   7122 O  O     . GLU B 2 399 ? 89.16100  38.23700  25.23900  1.000 339.84000 ? 399 GLU B O     1 
ATOM   7123 C  CB    . GLU B 2 399 ? 90.52200  37.05000  27.87000  1.000 364.66000 ? 399 GLU B CB    1 
ATOM   7124 C  CG    . GLU B 2 399 ? 91.69700  36.74300  28.89100  1.000 371.38000 ? 399 GLU B CG    1 
ATOM   7125 C  CD    . GLU B 2 399 ? 92.21700  35.28600  28.89400  1.000 371.93000 ? 399 GLU B CD    1 
ATOM   7126 O  OE1   . GLU B 2 399 ? 93.09400  34.95400  29.73800  1.000 370.25000 ? 399 GLU B OE1   1 
ATOM   7127 O  OE2   . GLU B 2 399 ? 91.75900  34.46900  28.05900  1.000 371.53000 ? 399 GLU B OE2   1 
ATOM   7128 N  N     . LYS B 2 400 ? 89.08900  35.98400  25.05000  1.000 326.60000 ? 400 LYS B N     1 
ATOM   7129 C  CA    . LYS B 2 400 ? 87.90600  35.97300  24.21900  1.000 328.15000 ? 400 LYS B CA    1 
ATOM   7130 C  C     . LYS B 2 400 ? 87.03800  34.78700  24.56000  1.000 332.29000 ? 400 LYS B C     1 
ATOM   7131 O  O     . LYS B 2 400 ? 87.50600  33.74200  25.00900  1.000 328.90000 ? 400 LYS B O     1 
ATOM   7132 C  CB    . LYS B 2 400 ? 88.23000  35.91300  22.75000  1.000 333.94000 ? 400 LYS B CB    1 
ATOM   7133 C  CG    . LYS B 2 400 ? 88.55000  37.24600  22.16800  1.000 333.28000 ? 400 LYS B CG    1 
ATOM   7134 C  CD    . LYS B 2 400 ? 88.49200  37.19000  20.65000  1.000 339.67000 ? 400 LYS B CD    1 
ATOM   7135 C  CE    . LYS B 2 400 ? 89.59300  38.05900  20.03200  1.000 344.66000 ? 400 LYS B CE    1 
ATOM   7136 N  NZ    . LYS B 2 400 ? 89.15800  38.92800  18.88800  1.000 324.56000 ? 400 LYS B NZ    1 
ATOM   7137 N  N     . ILE B 2 401 ? 85.75700  34.98600  24.33500  1.000 332.62000 ? 401 ILE B N     1 
ATOM   7138 C  CA    . ILE B 2 401 ? 84.74300  33.95900  24.45100  1.000 330.03000 ? 401 ILE B CA    1 
ATOM   7139 C  C     . ILE B 2 401 ? 84.37900  33.59600  23.01300  1.000 328.51000 ? 401 ILE B C     1 
ATOM   7140 O  O     . ILE B 2 401 ? 84.18300  34.48700  22.17600  1.000 323.55000 ? 401 ILE B O     1 
ATOM   7141 C  CB    . ILE B 2 401 ? 83.52900  34.47300  25.25700  1.000 335.25000 ? 401 ILE B CB    1 
ATOM   7142 C  CG1   . ILE B 2 401 ? 83.94700  35.05700  26.60800  1.000 340.75000 ? 401 ILE B CG1   1 
ATOM   7143 C  CG2   . ILE B 2 401 ? 82.52400  33.36700  25.51200  1.000 334.95000 ? 401 ILE B CG2   1 
ATOM   7144 C  CD1   . ILE B 2 401 ? 82.77400  35.62300  27.46900  1.000 331.77000 ? 401 ILE B CD1   1 
ATOM   7145 N  N     . LEU B 2 402 ? 84.37400  32.30800  22.69200  1.000 316.56000 ? 402 LEU B N     1 
ATOM   7146 C  CA    . LEU B 2 402 ? 84.07700  31.85400  21.33400  1.000 317.17000 ? 402 LEU B CA    1 
ATOM   7147 C  C     . LEU B 2 402 ? 82.80800  31.00500  21.33300  1.000 309.29000 ? 402 LEU B C     1 
ATOM   7148 O  O     . LEU B 2 402 ? 82.83500  29.92700  21.90600  1.000 304.41000 ? 402 LEU B O     1 
ATOM   7149 C  CB    . LEU B 2 402 ? 85.25900  31.04400  20.82000  1.000 313.87000 ? 402 LEU B CB    1 
ATOM   7150 C  CG    . LEU B 2 402 ? 86.16600  31.92600  20.02100  1.000 311.05000 ? 402 LEU B CG    1 
ATOM   7151 C  CD1   . LEU B 2 402 ? 86.73100  33.04600  20.86800  1.000 312.70000 ? 402 LEU B CD1   1 
ATOM   7152 C  CD2   . LEU B 2 402 ? 87.24600  31.04300  19.51400  1.000 312.60000 ? 402 LEU B CD2   1 
ATOM   7153 N  N     . ILE B 2 403 ? 81.70500  31.44300  20.69900  1.000 320.00000 ? 403 ILE B N     1 
ATOM   7154 C  CA    . ILE B 2 403 ? 80.47400  30.64200  20.72400  1.000 314.36000 ? 403 ILE B CA    1 
ATOM   7155 C  C     . ILE B 2 403 ? 80.34800  30.00900  19.34500  1.000 311.53000 ? 403 ILE B C     1 
ATOM   7156 O  O     . ILE B 2 403 ? 80.51300  30.71900  18.35800  1.000 311.65000 ? 403 ILE B O     1 
ATOM   7157 C  CB    . ILE B 2 403 ? 79.20200  31.44800  21.13400  1.000 308.51000 ? 403 ILE B CB    1 
ATOM   7158 C  CG1   . ILE B 2 403 ? 79.44200  32.94600  21.26800  1.000 315.41000 ? 403 ILE B CG1   1 
ATOM   7159 C  CG2   . ILE B 2 403 ? 78.35700  30.71400  22.38700  1.000 307.41000 ? 403 ILE B CG2   1 
ATOM   7160 C  CD1   . ILE B 2 403 ? 78.20800  33.76600  21.70000  1.000 321.10000 ? 403 ILE B CD1   1 
ATOM   7161 N  N     . SER B 2 404 ? 80.12500  28.67400  19.28800  1.000 320.03000 ? 404 SER B N     1 
ATOM   7162 C  CA    . SER B 2 404 ? 79.65300  27.95100  18.09700  1.000 323.06000 ? 404 SER B CA    1 
ATOM   7163 C  C     . SER B 2 404 ? 78.46900  28.66700  17.45700  1.000 326.74000 ? 404 SER B C     1 
ATOM   7164 O  O     . SER B 2 404 ? 77.53300  29.06800  18.16600  1.000 325.57000 ? 404 SER B O     1 
ATOM   7165 C  CB    . SER B 2 404 ? 79.23700  26.52500  18.48900  1.000 321.00000 ? 404 SER B CB    1 
ATOM   7166 O  OG    . SER B 2 404 ? 78.74000  25.86500  17.35100  1.000 317.21000 ? 404 SER B OG    1 
ATOM   7167 N  N     . ASN B 2 405 ? 78.50000  28.78300  16.11000  1.000 328.81000 ? 405 ASN B N     1 
ATOM   7168 C  CA    . ASN B 2 405 ? 77.50400  29.57000  15.36400  1.000 322.72000 ? 405 ASN B CA    1 
ATOM   7169 C  C     . ASN B 2 405 ? 76.38400  28.67300  14.85800  1.000 316.76000 ? 405 ASN B C     1 
ATOM   7170 O  O     . ASN B 2 405 ? 75.41300  29.11900  14.20000  1.000 312.02000 ? 405 ASN B O     1 
ATOM   7171 C  CB    . ASN B 2 405 ? 78.16600  30.25300  14.17000  1.000 315.80000 ? 405 ASN B CB    1 
ATOM   7172 C  CG    . ASN B 2 405 ? 78.73300  29.25800  13.14900  1.000 314.41000 ? 405 ASN B CG    1 
ATOM   7173 O  OD1   . ASN B 2 405 ? 78.55100  28.05600  13.25500  1.000 316.67000 ? 405 ASN B OD1   1 
ATOM   7174 N  ND2   . ASN B 2 405 ? 79.45200  29.78500  12.14700  1.000 314.60000 ? 405 ASN B ND2   1 
ATOM   7175 N  N     . LYS B 2 406 ? 76.54700  27.38000  15.13600  1.000 317.26000 ? 406 LYS B N     1 
ATOM   7176 C  CA    . LYS B 2 406 ? 75.57400  26.37400  14.76700  1.000 312.37000 ? 406 LYS B CA    1 
ATOM   7177 C  C     . LYS B 2 406 ? 75.14900  25.61000  16.00800  1.000 311.06000 ? 406 LYS B C     1 
ATOM   7178 O  O     . LYS B 2 406 ? 76.01300  25.19600  16.78500  1.000 312.60000 ? 406 LYS B O     1 
ATOM   7179 C  CB    . LYS B 2 406 ? 76.15500  25.43000  13.73800  1.000 312.33000 ? 406 LYS B CB    1 
ATOM   7180 C  CG    . LYS B 2 406 ? 76.15000  25.97500  12.35000  1.000 313.67000 ? 406 LYS B CG    1 
ATOM   7181 C  CD    . LYS B 2 406 ? 74.78100  25.94700  11.64000  1.000 309.54000 ? 406 LYS B CD    1 
ATOM   7182 C  CE    . LYS B 2 406 ? 74.77900  24.92800  10.49200  1.000 313.57000 ? 406 LYS B CE    1 
ATOM   7183 N  NZ    . LYS B 2 406 ? 73.85000  23.78200  10.74600  1.000 320.89000 ? 406 LYS B NZ    1 
ATOM   7184 N  N     . PRO B 2 407 ? 73.85900  25.37200  16.20300  1.000 306.35000 ? 407 PRO B N     1 
ATOM   7185 C  CA    . PRO B 2 407 ? 73.30100  25.13500  17.52600  1.000 299.45000 ? 407 PRO B CA    1 
ATOM   7186 C  C     . PRO B 2 407 ? 73.34800  23.64900  17.74100  1.000 301.61000 ? 407 PRO B C     1 
ATOM   7187 O  O     . PRO B 2 407 ? 73.57200  22.89100  16.79800  1.000 303.23000 ? 407 PRO B O     1 
ATOM   7188 C  CB    . PRO B 2 407 ? 71.85700  25.65800  17.36200  1.000 298.76000 ? 407 PRO B CB    1 
ATOM   7189 C  CG    . PRO B 2 407 ? 71.47800  25.24400  15.92300  1.000 302.96000 ? 407 PRO B CG    1 
ATOM   7190 C  CD    . PRO B 2 407 ? 72.80500  25.51400  15.15400  1.000 308.25000 ? 407 PRO B CD    1 
ATOM   7191 N  N     . LEU B 2 408 ? 73.21800  23.23900  18.99600  1.000 301.65000 ? 408 LEU B N     1 
ATOM   7192 C  CA    . LEU B 2 408 ? 73.21200  21.78800  19.21500  1.000 306.31000 ? 408 LEU B CA    1 
ATOM   7193 C  C     . LEU B 2 408 ? 72.09800  21.19100  18.35400  1.000 302.92000 ? 408 LEU B C     1 
ATOM   7194 O  O     . LEU B 2 408 ? 71.01500  21.76500  18.25200  1.000 299.25000 ? 408 LEU B O     1 
ATOM   7195 C  CB    . LEU B 2 408 ? 73.00700  21.41500  20.68900  1.000 308.68000 ? 408 LEU B CB    1 
ATOM   7196 C  CG    . LEU B 2 408 ? 73.37700  22.43800  21.77000  1.000 301.67000 ? 408 LEU B CG    1 
ATOM   7197 C  CD1   . LEU B 2 408 ? 72.34000  23.65000  21.96800  1.000 295.47000 ? 408 LEU B CD1   1 
ATOM   7198 C  CD2   . LEU B 2 408 ? 73.92400  21.77100  23.15600  1.000 303.36000 ? 408 LEU B CD2   1 
ATOM   7199 N  N     . LYS B 2 409 ? 72.40800  20.11700  17.63400  1.000 301.56000 ? 409 LYS B N     1 
ATOM   7200 C  CA    . LYS B 2 409 ? 71.42700  19.35300  16.89100  1.000 295.48000 ? 409 LYS B CA    1 
ATOM   7201 C  C     . LYS B 2 409 ? 70.95700  18.21100  17.76700  1.000 296.83000 ? 409 LYS B C     1 
ATOM   7202 O  O     . LYS B 2 409 ? 71.75300  17.58600  18.47300  1.000 302.26000 ? 409 LYS B O     1 
ATOM   7203 C  CB    . LYS B 2 409 ? 72.00700  18.79300  15.58500  1.000 293.61000 ? 409 LYS B CB    1 
ATOM   7204 N  N     . PHE B 2 410 ? 69.66600  17.94800  17.73900  1.000 284.34000 ? 410 PHE B N     1 
ATOM   7205 C  CA    . PHE B 2 410 ? 69.11000  16.84500  18.49900  1.000 283.13000 ? 410 PHE B CA    1 
ATOM   7206 C  C     . PHE B 2 410 ? 68.56200  15.87000  17.48300  1.000 281.45000 ? 410 PHE B C     1 
ATOM   7207 O  O     . PHE B 2 410 ? 67.94000  16.28400  16.50700  1.000 277.94000 ? 410 PHE B O     1 
ATOM   7208 C  CB    . PHE B 2 410 ? 68.03200  17.33600  19.46900  1.000 287.76000 ? 410 PHE B CB    1 
ATOM   7209 C  CG    . PHE B 2 410 ? 68.54700  18.32100  20.49500  1.000 286.52000 ? 410 PHE B CG    1 
ATOM   7210 C  CD1   . PHE B 2 410 ? 68.50800  18.01000  21.84900  1.000 295.09000 ? 410 PHE B CD1   1 
ATOM   7211 C  CD2   . PHE B 2 410 ? 69.09700  19.53700  20.10700  1.000 284.65000 ? 410 PHE B CD2   1 
ATOM   7212 C  CE1   . PHE B 2 410 ? 68.98700  18.89000  22.79800  1.000 299.46000 ? 410 PHE B CE1   1 
ATOM   7213 C  CE2   . PHE B 2 410 ? 69.59500  20.42500  21.05100  1.000 292.64000 ? 410 PHE B CE2   1 
ATOM   7214 C  CZ    . PHE B 2 410 ? 69.53700  20.09900  22.40700  1.000 299.72000 ? 410 PHE B CZ    1 
ATOM   7215 N  N     . PHE B 2 411 ? 68.88000  14.60600  17.63400  1.000 272.75000 ? 411 PHE B N     1 
ATOM   7216 C  CA    . PHE B 2 411 ? 68.42000  13.61600  16.68100  1.000 269.40000 ? 411 PHE B CA    1 
ATOM   7217 C  C     . PHE B 2 411 ? 67.43000  12.73300  17.40300  1.000 268.28000 ? 411 PHE B C     1 
ATOM   7218 O  O     . PHE B 2 411 ? 67.75900  12.16400  18.45100  1.000 276.16000 ? 411 PHE B O     1 
ATOM   7219 C  CB    . PHE B 2 411 ? 69.57600  12.80800  16.10700  1.000 269.25000 ? 411 PHE B CB    1 
ATOM   7220 N  N     . GLY B 2 412 ? 66.20800  12.67300  16.86600  1.000 277.86000 ? 412 GLY B N     1 
ATOM   7221 C  CA    . GLY B 2 412 ? 65.15700  11.85100  17.41500  1.000 281.53000 ? 412 GLY B CA    1 
ATOM   7222 C  C     . GLY B 2 412 ? 64.50300  10.95600  16.37700  1.000 282.80000 ? 412 GLY B C     1 
ATOM   7223 O  O     . GLY B 2 412 ? 63.79400  11.43000  15.47600  1.000 282.34000 ? 412 GLY B O     1 
ATOM   7224 N  N     . LYS B 2 413 ? 64.77500  9.65700   16.47500  1.000 288.76000 ? 413 LYS B N     1 
ATOM   7225 C  CA    . LYS B 2 413 ? 63.86500  8.67700   15.92100  1.000 287.04000 ? 413 LYS B CA    1 
ATOM   7226 C  C     . LYS B 2 413 ? 62.48400  8.96100   16.47500  1.000 289.33000 ? 413 LYS B C     1 
ATOM   7227 O  O     . LYS B 2 413 ? 62.32600  9.18000   17.68300  1.000 293.78000 ? 413 LYS B O     1 
ATOM   7228 C  CB    . LYS B 2 413 ? 64.27700  7.26600   16.31000  1.000 297.13000 ? 413 LYS B CB    1 
ATOM   7229 C  CG    . LYS B 2 413 ? 65.74200  7.02100   16.41000  1.000 301.22000 ? 413 LYS B CG    1 
ATOM   7230 C  CD    . LYS B 2 413 ? 66.04200  5.99400   17.48300  1.000 305.06000 ? 413 LYS B CD    1 
ATOM   7231 C  CE    . LYS B 2 413 ? 67.42400  5.39300   17.28700  1.000 312.60000 ? 413 LYS B CE    1 
ATOM   7232 N  NZ    . LYS B 2 413 ? 67.90100  4.70800   18.51200  1.000 305.23000 ? 413 LYS B NZ    1 
ATOM   7233 N  N     . MET B 2 414 ? 61.50000  8.93700   15.57000  1.000 288.80000 ? 414 MET B N     1 
ATOM   7234 C  CA    . MET B 2 414 ? 60.07000  9.19400   15.74800  1.000 295.12000 ? 414 MET B CA    1 
ATOM   7235 C  C     . MET B 2 414 ? 59.76200  10.59000  15.19600  1.000 292.97000 ? 414 MET B C     1 
ATOM   7236 O  O     . MET B 2 414 ? 60.26500  11.60600  15.69600  1.000 289.68000 ? 414 MET B O     1 
ATOM   7237 C  CB    . MET B 2 414 ? 59.57600  9.02300   17.20900  1.000 298.11000 ? 414 MET B CB    1 
ATOM   7238 C  CG    . MET B 2 414 ? 59.41800  7.53000   17.72900  1.000 284.97000 ? 414 MET B CG    1 
ATOM   7239 S  SD    . MET B 2 414 ? 58.29800  6.35600   16.86900  1.000 280.05000 ? 414 MET B SD    1 
ATOM   7240 C  CE    . MET B 2 414 ? 57.48600  5.49600   18.23500  1.000 269.84000 ? 414 MET B CE    1 
ATOM   7241 N  N     . SER B 2 415 ? 59.00100  10.63500  14.10000  1.000 301.15000 ? 415 SER B N     1 
ATOM   7242 C  CA    . SER B 2 415 ? 58.55200  11.88500  13.49200  1.000 296.17000 ? 415 SER B CA    1 
ATOM   7243 C  C     . SER B 2 415 ? 57.35600  11.58800  12.59300  1.000 293.50000 ? 415 SER B C     1 
ATOM   7244 O  O     . SER B 2 415 ? 56.90000  10.44300  12.47700  1.000 288.99000 ? 415 SER B O     1 
ATOM   7245 C  CB    . SER B 2 415 ? 59.68100  12.57500  12.72800  1.000 293.08000 ? 415 SER B CB    1 
ATOM   7246 O  OG    . SER B 2 415 ? 59.67700  13.95200  13.02000  1.000 294.16000 ? 415 SER B OG    1 
ATOM   7247 N  N     . TYR B 2 416 ? 56.86200  12.63700  11.94700  1.000 291.03000 ? 416 TYR B N     1 
ATOM   7248 C  CA    . TYR B 2 416 ? 55.58300  12.61000  11.26600  1.000 291.28000 ? 416 TYR B CA    1 
ATOM   7249 C  C     . TYR B 2 416 ? 55.75000  12.89600  9.78100   1.000 288.44000 ? 416 TYR B C     1 
ATOM   7250 O  O     . TYR B 2 416 ? 56.64000  13.65000  9.37500   1.000 287.23000 ? 416 TYR B O     1 
ATOM   7251 C  CB    . TYR B 2 416 ? 54.63100  13.62400  11.90600  1.000 293.70000 ? 416 TYR B CB    1 
ATOM   7252 C  CG    . TYR B 2 416 ? 55.20800  15.03100  12.07200  1.000 290.11000 ? 416 TYR B CG    1 
ATOM   7253 C  CD1   . TYR B 2 416 ? 55.09100  15.97400  11.05100  1.000 290.98000 ? 416 TYR B CD1   1 
ATOM   7254 C  CD2   . TYR B 2 416 ? 55.86100  15.41500  13.24600  1.000 284.09000 ? 416 TYR B CD2   1 
ATOM   7255 C  CE1   . TYR B 2 416 ? 55.59900  17.25800  11.18800  1.000 285.06000 ? 416 TYR B CE1   1 
ATOM   7256 C  CE2   . TYR B 2 416 ? 56.37500  16.70500  13.39700  1.000 280.25000 ? 416 TYR B CE2   1 
ATOM   7257 C  CZ    . TYR B 2 416 ? 56.23700  17.61500  12.35600  1.000 280.71000 ? 416 TYR B CZ    1 
ATOM   7258 O  OH    . TYR B 2 416 ? 56.72100  18.89200  12.44500  1.000 278.58000 ? 416 TYR B OH    1 
ATOM   7259 N  N     . VAL B 2 417 ? 54.89100  12.27200  8.97100   1.000 272.15000 ? 417 VAL B N     1 
ATOM   7260 C  CA    . VAL B 2 417 ? 54.82400  12.60000  7.55500   1.000 274.73000 ? 417 VAL B CA    1 
ATOM   7261 C  C     . VAL B 2 417 ? 54.33600  14.02800  7.40500   1.000 276.61000 ? 417 VAL B C     1 
ATOM   7262 O  O     . VAL B 2 417 ? 53.27000  14.38700  7.92200   1.000 284.18000 ? 417 VAL B O     1 
ATOM   7263 C  CB    . VAL B 2 417 ? 53.89700  11.59500  6.85200   1.000 275.06000 ? 417 VAL B CB    1 
ATOM   7264 C  CG1   . VAL B 2 417 ? 54.44900  10.22700  7.01900   1.000 271.33000 ? 417 VAL B CG1   1 
ATOM   7265 C  CG2   . VAL B 2 417 ? 52.48200  11.66400  7.37700   1.000 284.50000 ? 417 VAL B CG2   1 
ATOM   7266 N  N     . THR B 2 418 ? 55.14300  14.86700  6.75600   1.000 288.41000 ? 418 THR B N     1 
ATOM   7267 C  CA    . THR B 2 418 ? 54.71300  16.23300  6.50300   1.000 291.16000 ? 418 THR B CA    1 
ATOM   7268 C  C     . THR B 2 418 ? 53.52600  16.20000  5.54600   1.000 293.09000 ? 418 THR B C     1 
ATOM   7269 O  O     . THR B 2 418 ? 53.51300  15.37800  4.61800   1.000 296.65000 ? 418 THR B O     1 
ATOM   7270 C  CB    . THR B 2 418 ? 55.85000  17.08400  5.93800   1.000 297.96000 ? 418 THR B CB    1 
ATOM   7271 O  OG1   . THR B 2 418 ? 55.48400  18.47000  5.89100   1.000 292.67000 ? 418 THR B OG1   1 
ATOM   7272 C  CG2   . THR B 2 418 ? 56.20800  16.64800  4.50400   1.000 300.45000 ? 418 THR B CG2   1 
ATOM   7273 N  N     . PRO B 2 419 ? 52.46700  17.00700  5.78300   1.000 302.56000 ? 419 PRO B N     1 
ATOM   7274 C  CA    . PRO B 2 419 ? 51.31200  16.98400  4.87100   1.000 298.81000 ? 419 PRO B CA    1 
ATOM   7275 C  C     . PRO B 2 419 ? 51.68400  17.64900  3.54200   1.000 295.04000 ? 419 PRO B C     1 
ATOM   7276 O  O     . PRO B 2 419 ? 51.38600  17.16200  2.43500   1.000 289.49000 ? 419 PRO B O     1 
ATOM   7277 C  CB    . PRO B 2 419 ? 50.23300  17.78700  5.62900   1.000 295.81000 ? 419 PRO B CB    1 
ATOM   7278 C  CG    . PRO B 2 419 ? 51.01200  18.66400  6.54800   1.000 294.88000 ? 419 PRO B CG    1 
ATOM   7279 C  CD    . PRO B 2 419 ? 52.26200  17.87100  6.95900   1.000 300.41000 ? 419 PRO B CD    1 
ATOM   7280 O  OP3   . DT  C 3 1   ? 42.69200  28.32500  12.19800  1.000 294.01000 ? 1   DT  C OP3   1 
ATOM   7281 P  P     . DT  C 3 1   ? 43.19300  28.98500  13.42400  1.000 297.39000 ? 1   DT  C P     1 
ATOM   7282 O  OP1   . DT  C 3 1   ? 44.28400  29.87300  12.95100  1.000 297.45000 ? 1   DT  C OP1   1 
ATOM   7283 O  OP2   . DT  C 3 1   ? 43.49200  27.85700  14.33700  1.000 301.08000 ? 1   DT  C OP2   1 
ATOM   7284 O  "O5'" . DT  C 3 1   ? 42.10400  29.88100  14.21400  1.000 302.70000 ? 1   DT  C "O5'" 1 
ATOM   7285 C  "C5'" . DT  C 3 1   ? 41.16400  30.70600  13.50300  1.000 298.89000 ? 1   DT  C "C5'" 1 
ATOM   7286 C  "C4'" . DT  C 3 1   ? 40.70600  31.89200  14.33800  1.000 293.54000 ? 1   DT  C "C4'" 1 
ATOM   7287 O  "O4'" . DT  C 3 1   ? 40.21400  31.44300  15.62600  1.000 290.98000 ? 1   DT  C "O4'" 1 
ATOM   7288 C  "C3'" . DT  C 3 1   ? 41.78200  32.95400  14.63900  1.000 295.78000 ? 1   DT  C "C3'" 1 
ATOM   7289 O  "O3'" . DT  C 3 1   ? 41.39100  34.20800  14.04800  1.000 300.92000 ? 1   DT  C "O3'" 1 
ATOM   7290 C  "C2'" . DT  C 3 1   ? 41.81900  33.02400  16.18400  1.000 294.59000 ? 1   DT  C "C2'" 1 
ATOM   7291 C  "C1'" . DT  C 3 1   ? 40.48300  32.43200  16.60400  1.000 297.29000 ? 1   DT  C "C1'" 1 
ATOM   7292 N  N1    . DT  C 3 1   ? 40.41500  31.76200  18.06800  1.000 307.19000 ? 1   DT  C N1    1 
ATOM   7293 C  C2    . DT  C 3 1   ? 39.61500  32.32800  19.07700  1.000 317.08000 ? 1   DT  C C2    1 
ATOM   7294 O  O2    . DT  C 3 1   ? 38.96700  33.36600  18.93200  1.000 321.28000 ? 1   DT  C O2    1 
ATOM   7295 N  N3    . DT  C 3 1   ? 39.59400  31.63100  20.27600  1.000 316.06000 ? 1   DT  C N3    1 
ATOM   7296 C  C4    . DT  C 3 1   ? 40.24700  30.45300  20.57400  1.000 310.75000 ? 1   DT  C C4    1 
ATOM   7297 O  O4    . DT  C 3 1   ? 40.18800  29.91800  21.68700  1.000 307.42000 ? 1   DT  C O4    1 
ATOM   7298 C  C5    . DT  C 3 1   ? 41.06700  29.90900  19.49900  1.000 303.77000 ? 1   DT  C C5    1 
ATOM   7299 C  C7    . DT  C 3 1   ? 41.85800  28.63900  19.70400  1.000 307.34000 ? 1   DT  C C7    1 
ATOM   7300 C  C6    . DT  C 3 1   ? 41.09800  30.57200  18.31100  1.000 304.18000 ? 1   DT  C C6    1 
ATOM   7301 P  P     . DG  C 3 2   ? 42.51100  35.32400  13.70000  1.000 300.94000 ? 2   DG  C P     1 
ATOM   7302 O  OP1   . DG  C 3 2   ? 42.24800  35.91900  12.37100  1.000 308.28000 ? 2   DG  C OP1   1 
ATOM   7303 O  OP2   . DG  C 3 2   ? 43.76500  34.58500  13.85700  1.000 301.99000 ? 2   DG  C OP2   1 
ATOM   7304 O  "O5'" . DG  C 3 2   ? 42.34600  36.38500  14.85900  1.000 296.71000 ? 2   DG  C "O5'" 1 
ATOM   7305 C  "C5'" . DG  C 3 2   ? 41.17300  36.39500  15.60500  1.000 300.94000 ? 2   DG  C "C5'" 1 
ATOM   7306 C  "C4'" . DG  C 3 2   ? 41.28700  37.36400  16.76900  1.000 309.65000 ? 2   DG  C "C4'" 1 
ATOM   7307 O  "O4'" . DG  C 3 2   ? 41.11500  36.61800  17.99700  1.000 318.62000 ? 2   DG  C "O4'" 1 
ATOM   7308 C  "C3'" . DG  C 3 2   ? 42.64400  38.10300  16.92100  1.000 316.11000 ? 2   DG  C "C3'" 1 
ATOM   7309 O  "O3'" . DG  C 3 2   ? 42.41400  39.34300  17.57100  1.000 320.23000 ? 2   DG  C "O3'" 1 
ATOM   7310 C  "C2'" . DG  C 3 2   ? 43.43500  37.16100  17.82200  1.000 319.45000 ? 2   DG  C "C2'" 1 
ATOM   7311 C  "C1'" . DG  C 3 2   ? 42.36100  36.54600  18.69800  1.000 321.35000 ? 2   DG  C "C1'" 1 
ATOM   7312 N  N9    . DG  C 3 2   ? 42.67800  35.15200  19.11900  1.000 319.69000 ? 2   DG  C N9    1 
ATOM   7313 C  C8    . DG  C 3 2   ? 43.60200  34.23300  18.51800  1.000 317.79000 ? 2   DG  C C8    1 
ATOM   7314 N  N7    . DG  C 3 2   ? 43.67200  33.10200  19.11300  1.000 317.48000 ? 2   DG  C N7    1 
ATOM   7315 C  C5    . DG  C 3 2   ? 42.78700  33.25100  20.18800  1.000 319.42000 ? 2   DG  C C5    1 
ATOM   7316 C  C6    . DG  C 3 2   ? 42.52000  32.34700  21.28300  1.000 322.86000 ? 2   DG  C C6    1 
ATOM   7317 O  O6    . DG  C 3 2   ? 42.86200  31.15200  21.44300  1.000 330.00000 ? 2   DG  C O6    1 
ATOM   7318 N  N1    . DG  C 3 2   ? 41.49100  32.85000  22.12100  1.000 322.26000 ? 2   DG  C N1    1 
ATOM   7319 C  C2    . DG  C 3 2   ? 40.96800  34.09900  22.03400  1.000 322.12000 ? 2   DG  C C2    1 
ATOM   7320 N  N2    . DG  C 3 2   ? 40.06500  34.44800  22.99600  1.000 325.78000 ? 2   DG  C N2    1 
ATOM   7321 N  N3    . DG  C 3 2   ? 41.28600  34.96800  21.08200  1.000 318.45000 ? 2   DG  C N3    1 
ATOM   7322 C  C4    . DG  C 3 2   ? 42.18800  34.49300  20.21700  1.000 319.40000 ? 2   DG  C C4    1 
ATOM   7323 P  P     . DA  C 3 3   ? 42.98600  40.74700  17.00500  1.000 310.21000 ? 3   DA  C P     1 
ATOM   7324 O  OP1   . DA  C 3 3   ? 42.71600  40.81900  15.54800  1.000 294.95000 ? 3   DA  C OP1   1 
ATOM   7325 O  OP2   . DA  C 3 3   ? 44.39200  40.80100  17.48200  1.000 307.50000 ? 3   DA  C OP2   1 
ATOM   7326 O  "O5'" . DA  C 3 3   ? 42.09500  41.79400  17.84700  1.000 324.28000 ? 3   DA  C "O5'" 1 
ATOM   7327 C  "C5'" . DA  C 3 3   ? 40.77100  41.38600  18.33200  1.000 336.09000 ? 3   DA  C "C5'" 1 
ATOM   7328 C  "C4'" . DA  C 3 3   ? 40.70500  41.16300  19.86600  1.000 345.07000 ? 3   DA  C "C4'" 1 
ATOM   7329 O  "O4'" . DA  C 3 3   ? 41.45900  39.98300  20.25500  1.000 337.09000 ? 3   DA  C "O4'" 1 
ATOM   7330 C  "C3'" . DA  C 3 3   ? 41.20600  42.31000  20.77000  1.000 344.50000 ? 3   DA  C "C3'" 1 
ATOM   7331 O  "O3'" . DA  C 3 3   ? 40.26200  42.54300  21.85400  1.000 332.62000 ? 3   DA  C "O3'" 1 
ATOM   7332 C  "C2'" . DA  C 3 3   ? 42.52800  41.76300  21.29500  1.000 337.54000 ? 3   DA  C "C2'" 1 
ATOM   7333 C  "C1'" . DA  C 3 3   ? 42.20400  40.28600  21.40900  1.000 329.42000 ? 3   DA  C "C1'" 1 
ATOM   7334 N  N9    . DA  C 3 3   ? 43.38100  39.45900  21.38600  1.000 321.76000 ? 3   DA  C N9    1 
ATOM   7335 C  C8    . DA  C 3 3   ? 44.52100  39.69400  20.67700  1.000 325.71000 ? 3   DA  C C8    1 
ATOM   7336 N  N7    . DA  C 3 3   ? 45.42800  38.76700  20.82500  1.000 324.43000 ? 3   DA  C N7    1 
ATOM   7337 C  C5    . DA  C 3 3   ? 44.83300  37.85900  21.68700  1.000 318.53000 ? 3   DA  C C5    1 
ATOM   7338 C  C6    . DA  C 3 3   ? 45.27400  36.64500  22.23800  1.000 314.85000 ? 3   DA  C C6    1 
ATOM   7339 N  N6    . DA  C 3 3   ? 46.47300  36.12300  21.99100  1.000 320.60000 ? 3   DA  C N6    1 
ATOM   7340 N  N1    . DA  C 3 3   ? 44.43100  35.98400  23.05300  1.000 307.40000 ? 3   DA  C N1    1 
ATOM   7341 C  C2    . DA  C 3 3   ? 43.23500  36.51400  23.30500  1.000 308.12000 ? 3   DA  C C2    1 
ATOM   7342 N  N3    . DA  C 3 3   ? 42.70800  37.64100  22.84600  1.000 311.51000 ? 3   DA  C N3    1 
ATOM   7343 C  C4    . DA  C 3 3   ? 43.56800  38.27200  22.03600  1.000 314.89000 ? 3   DA  C C4    1 
ATOM   7344 P  P     . DG  C 3 4   ? 40.57000  43.61000  23.02300  1.000 331.90000 ? 4   DG  C P     1 
ATOM   7345 O  OP1   . DG  C 3 4   ? 39.32600  43.73400  23.81600  1.000 322.41000 ? 4   DG  C OP1   1 
ATOM   7346 O  OP2   . DG  C 3 4   ? 41.25200  44.81100  22.49400  1.000 321.09000 ? 4   DG  C OP2   1 
ATOM   7347 O  "O5'" . DG  C 3 4   ? 41.71600  42.92000  23.86500  1.000 322.84000 ? 4   DG  C "O5'" 1 
ATOM   7348 C  "C5'" . DG  C 3 4   ? 41.68800  42.96900  25.24500  1.000 326.16000 ? 4   DG  C "C5'" 1 
ATOM   7349 C  "C4'" . DG  C 3 4   ? 42.03000  41.60800  25.79300  1.000 329.62000 ? 4   DG  C "C4'" 1 
ATOM   7350 O  "O4'" . DG  C 3 4   ? 42.80500  40.88400  24.81300  1.000 321.57000 ? 4   DG  C "O4'" 1 
ATOM   7351 C  "C3'" . DG  C 3 4   ? 42.87100  41.59900  27.06100  1.000 335.19000 ? 4   DG  C "C3'" 1 
ATOM   7352 O  "O3'" . DG  C 3 4   ? 41.98900  41.77500  28.25300  1.000 337.01000 ? 4   DG  C "O3'" 1 
ATOM   7353 C  "C2'" . DG  C 3 4   ? 43.52500  40.20400  26.98100  1.000 330.01000 ? 4   DG  C "C2'" 1 
ATOM   7354 C  "C1'" . DG  C 3 4   ? 43.50000  39.85300  25.46700  1.000 321.52000 ? 4   DG  C "C1'" 1 
ATOM   7355 N  N9    . DG  C 3 4   ? 44.84000  39.72200  24.85900  1.000 319.91000 ? 4   DG  C N9    1 
ATOM   7356 C  C8    . DG  C 3 4   ? 45.55800  40.67900  24.18500  1.000 312.09000 ? 4   DG  C C8    1 
ATOM   7357 N  N7    . DG  C 3 4   ? 46.73100  40.26300  23.78300  1.000 311.82000 ? 4   DG  C N7    1 
ATOM   7358 C  C5    . DG  C 3 4   ? 46.78600  38.94600  24.21400  1.000 318.40000 ? 4   DG  C C5    1 
ATOM   7359 C  C6    . DG  C 3 4   ? 47.81200  37.97500  24.06200  1.000 317.90000 ? 4   DG  C C6    1 
ATOM   7360 O  O6    . DG  C 3 4   ? 48.91300  38.08600  23.50800  1.000 316.85000 ? 4   DG  C O6    1 
ATOM   7361 N  N1    . DG  C 3 4   ? 47.45900  36.76900  24.66300  1.000 320.87000 ? 4   DG  C N1    1 
ATOM   7362 C  C2    . DG  C 3 4   ? 46.27000  36.53300  25.31100  1.000 320.09000 ? 4   DG  C C2    1 
ATOM   7363 N  N2    . DG  C 3 4   ? 46.11600  35.30800  25.80500  1.000 316.84000 ? 4   DG  C N2    1 
ATOM   7364 N  N3    . DG  C 3 4   ? 45.30100  37.42400  25.45200  1.000 322.27000 ? 4   DG  C N3    1 
ATOM   7365 C  C4    . DG  C 3 4   ? 45.62800  38.60100  24.88000  1.000 320.82000 ? 4   DG  C C4    1 
ATOM   7366 P  P     . DG  C 3 5   ? 42.49800  42.40700  29.66500  1.000 337.46000 ? 5   DG  C P     1 
ATOM   7367 O  OP1   . DG  C 3 5   ? 41.30300  42.62200  30.52000  1.000 334.10000 ? 5   DG  C OP1   1 
ATOM   7368 O  OP2   . DG  C 3 5   ? 43.41800  43.54000  29.49300  1.000 322.35000 ? 5   DG  C OP2   1 
ATOM   7369 O  "O5'" . DG  C 3 5   ? 43.32100  41.22500  30.33200  1.000 316.16000 ? 5   DG  C "O5'" 1 
ATOM   7370 C  "C5'" . DG  C 3 5   ? 42.74400  39.91200  30.39100  1.000 322.43000 ? 5   DG  C "C5'" 1 
ATOM   7371 C  "C4'" . DG  C 3 5   ? 43.80400  38.90400  30.77900  1.000 319.87000 ? 5   DG  C "C4'" 1 
ATOM   7372 O  "O4'" . DG  C 3 5   ? 44.64500  38.62400  29.62700  1.000 321.06000 ? 5   DG  C "O4'" 1 
ATOM   7373 C  "C3'" . DG  C 3 5   ? 44.75100  39.39400  31.87500  1.000 320.22000 ? 5   DG  C "C3'" 1 
ATOM   7374 O  "O3'" . DG  C 3 5   ? 44.97000  38.36800  32.88200  1.000 328.40000 ? 5   DG  C "O3'" 1 
ATOM   7375 C  "C2'" . DG  C 3 5   ? 46.02000  39.74500  31.11100  1.000 316.04000 ? 5   DG  C "C2'" 1 
ATOM   7376 C  "C1'" . DG  C 3 5   ? 46.00100  38.73800  29.99100  1.000 317.48000 ? 5   DG  C "C1'" 1 
ATOM   7377 N  N9    . DG  C 3 5   ? 46.80600  39.15800  28.82500  1.000 323.65000 ? 5   DG  C N9    1 
ATOM   7378 C  C8    . DG  C 3 5   ? 46.64800  40.30600  28.08000  1.000 325.43000 ? 5   DG  C C8    1 
ATOM   7379 N  N7    . DG  C 3 5   ? 47.51000  40.44100  27.10200  1.000 324.90000 ? 5   DG  C N7    1 
ATOM   7380 C  C5    . DG  C 3 5   ? 48.31900  39.30800  27.21800  1.000 322.14000 ? 5   DG  C C5    1 
ATOM   7381 C  C6    . DG  C 3 5   ? 49.43900  38.90500  26.44100  1.000 316.82000 ? 5   DG  C C6    1 
ATOM   7382 O  O6    . DG  C 3 5   ? 49.94900  39.48100  25.46400  1.000 310.76000 ? 5   DG  C O6    1 
ATOM   7383 N  N1    . DG  C 3 5   ? 49.96300  37.68700  26.88800  1.000 317.81000 ? 5   DG  C N1    1 
ATOM   7384 C  C2    . DG  C 3 5   ? 49.46800  36.95400  27.95000  1.000 319.39000 ? 5   DG  C C2    1 
ATOM   7385 N  N2    . DG  C 3 5   ? 50.12300  35.81200  28.23400  1.000 315.47000 ? 5   DG  C N2    1 
ATOM   7386 N  N3    . DG  C 3 5   ? 48.43300  37.33200  28.70600  1.000 322.22000 ? 5   DG  C N3    1 
ATOM   7387 C  C4    . DG  C 3 5   ? 47.90400  38.50800  28.28100  1.000 322.48000 ? 5   DG  C C4    1 
ATOM   7388 P  P     . DT  C 3 6   ? 46.14100  38.52800  33.98700  1.000 351.39000 ? 6   DT  C P     1 
ATOM   7389 O  OP1   . DT  C 3 6   ? 45.71600  37.99900  35.30600  1.000 341.92000 ? 6   DT  C OP1   1 
ATOM   7390 O  OP2   . DT  C 3 6   ? 46.62300  39.92800  33.93600  1.000 349.88000 ? 6   DT  C OP2   1 
ATOM   7391 O  "O5'" . DT  C 3 6   ? 47.29400  37.58100  33.41100  1.000 339.46000 ? 6   DT  C "O5'" 1 
ATOM   7392 C  "C5'" . DT  C 3 6   ? 46.99400  36.23800  33.03400  1.000 332.04000 ? 6   DT  C "C5'" 1 
ATOM   7393 C  "C4'" . DT  C 3 6   ? 48.25300  35.41900  33.04500  1.000 332.65000 ? 6   DT  C "C4'" 1 
ATOM   7394 O  "O4'" . DT  C 3 6   ? 49.01300  35.74200  31.84100  1.000 329.30000 ? 6   DT  C "O4'" 1 
ATOM   7395 C  "C3'" . DT  C 3 6   ? 49.14900  35.73700  34.24100  1.000 333.25000 ? 6   DT  C "C3'" 1 
ATOM   7396 O  "O3'" . DT  C 3 6   ? 49.76200  34.51000  34.81400  1.000 330.26000 ? 6   DT  C "O3'" 1 
ATOM   7397 C  "C2'" . DT  C 3 6   ? 50.15600  36.75800  33.67800  1.000 335.56000 ? 6   DT  C "C2'" 1 
ATOM   7398 C  "C1'" . DT  C 3 6   ? 50.15800  36.49500  32.16300  1.000 334.32000 ? 6   DT  C "C1'" 1 
ATOM   7399 N  N1    . DT  C 3 6   ? 50.27000  37.75900  31.25700  1.000 333.30000 ? 6   DT  C N1    1 
ATOM   7400 C  C2    . DT  C 3 6   ? 51.15900  37.72100  30.21500  1.000 331.83000 ? 6   DT  C C2    1 
ATOM   7401 O  O2    . DT  C 3 6   ? 51.78500  36.71600  29.92400  1.000 333.60000 ? 6   DT  C O2    1 
ATOM   7402 N  N3    . DT  C 3 6   ? 51.24700  38.86500  29.46900  1.000 328.68000 ? 6   DT  C N3    1 
ATOM   7403 C  C4    . DT  C 3 6   ? 50.58400  40.04800  29.66500  1.000 325.71000 ? 6   DT  C C4    1 
ATOM   7404 O  O4    . DT  C 3 6   ? 50.76400  41.02100  28.93500  1.000 324.70000 ? 6   DT  C O4    1 
ATOM   7405 C  C5    . DT  C 3 6   ? 49.67200  40.06100  30.80900  1.000 326.23000 ? 6   DT  C C5    1 
ATOM   7406 C  C7    . DT  C 3 6   ? 48.88600  41.30400  31.15900  1.000 323.34000 ? 6   DT  C C7    1 
ATOM   7407 C  C6    . DT  C 3 6   ? 49.56300  38.91900  31.54100  1.000 330.42000 ? 6   DT  C C6    1 
ATOM   7408 P  P     . DA  C 3 7   ? 51.00700  34.59100  35.83900  1.000 337.41000 ? 7   DA  C P     1 
ATOM   7409 O  OP1   . DA  C 3 7   ? 51.15600  33.35700  36.64900  1.000 350.46000 ? 7   DA  C OP1   1 
ATOM   7410 O  OP2   . DA  C 3 7   ? 51.05800  35.94400  36.42800  1.000 323.43000 ? 7   DA  C OP2   1 
ATOM   7411 O  "O5'" . DA  C 3 7   ? 52.22200  34.47100  34.86100  1.000 325.93000 ? 7   DA  C "O5'" 1 
ATOM   7412 C  "C5'" . DA  C 3 7   ? 52.40500  33.28900  34.23200  1.000 327.98000 ? 7   DA  C "C5'" 1 
ATOM   7413 C  "C4'" . DA  C 3 7   ? 53.73200  33.26300  33.59000  1.000 333.23000 ? 7   DA  C "C4'" 1 
ATOM   7414 O  "O4'" . DA  C 3 7   ? 53.81500  34.37900  32.66600  1.000 346.49000 ? 7   DA  C "O4'" 1 
ATOM   7415 C  "C3'" . DA  C 3 7   ? 54.84800  33.44600  34.57700  1.000 329.34000 ? 7   DA  C "C3'" 1 
ATOM   7416 O  "O3'" . DA  C 3 7   ? 55.91500  32.65400  34.24100  1.000 331.71000 ? 7   DA  C "O3'" 1 
ATOM   7417 C  "C2'" . DA  C 3 7   ? 55.17400  34.94100  34.51800  1.000 331.34000 ? 7   DA  C "C2'" 1 
ATOM   7418 C  "C1'" . DA  C 3 7   ? 54.79800  35.31800  33.08200  1.000 342.12000 ? 7   DA  C "C1'" 1 
ATOM   7419 N  N9    . DA  C 3 7   ? 54.25400  36.70300  32.92600  1.000 342.13000 ? 7   DA  C N9    1 
ATOM   7420 C  C8    . DA  C 3 7   ? 53.25900  37.28300  33.66600  1.000 337.03000 ? 7   DA  C C8    1 
ATOM   7421 N  N7    . DA  C 3 7   ? 52.97500  38.52300  33.32000  1.000 339.95000 ? 7   DA  C N7    1 
ATOM   7422 C  C5    . DA  C 3 7   ? 53.83400  38.78500  32.26300  1.000 340.43000 ? 7   DA  C C5    1 
ATOM   7423 C  C6    . DA  C 3 7   ? 54.02100  39.93100  31.44800  1.000 333.87000 ? 7   DA  C C6    1 
ATOM   7424 N  N6    . DA  C 3 7   ? 53.31700  41.05900  31.59100  1.000 331.89000 ? 7   DA  C N6    1 
ATOM   7425 N  N1    . DA  C 3 7   ? 54.95700  39.86900  30.48000  1.000 329.27000 ? 7   DA  C N1    1 
ATOM   7426 C  C2    . DA  C 3 7   ? 55.65700  38.73200  30.33500  1.000 331.87000 ? 7   DA  C C2    1 
ATOM   7427 N  N3    . DA  C 3 7   ? 55.57400  37.59500  31.03800  1.000 343.80000 ? 7   DA  C N3    1 
ATOM   7428 C  C4    . DA  C 3 7   ? 54.63500  37.68300  31.99900  1.000 343.85000 ? 7   DA  C C4    1 
ATOM   7429 P  P     . DG  C 3 8   ? 56.63200  31.89900  35.43900  1.000 360.20000 ? 8   DG  C P     1 
ATOM   7430 O  OP1   . DG  C 3 8   ? 57.55000  30.88400  34.87400  1.000 333.47000 ? 8   DG  C OP1   1 
ATOM   7431 O  OP2   . DG  C 3 8   ? 55.52800  31.55500  36.37300  1.000 344.98000 ? 8   DG  C OP2   1 
ATOM   7432 O  "O5'" . DG  C 3 8   ? 57.43300  33.07600  36.16000  1.000 339.50000 ? 8   DG  C "O5'" 1 
ATOM   7433 C  "C5'" . DG  C 3 8   ? 58.80200  33.26300  35.91000  1.000 331.15000 ? 8   DG  C "C5'" 1 
ATOM   7434 C  "C4'" . DG  C 3 8   ? 59.01000  33.67200  34.48600  1.000 324.84000 ? 8   DG  C "C4'" 1 
ATOM   7435 O  "O4'" . DG  C 3 8   ? 58.26900  34.86500  34.21600  1.000 329.77000 ? 8   DG  C "O4'" 1 
ATOM   7436 C  "C3'" . DG  C 3 8   ? 60.40500  34.08000  34.13300  1.000 322.25000 ? 8   DG  C "C3'" 1 
ATOM   7437 O  "O3'" . DG  C 3 8   ? 61.25000  32.94600  34.03100  1.000 331.35000 ? 8   DG  C "O3'" 1 
ATOM   7438 C  "C2'" . DG  C 3 8   ? 60.14800  34.74000  32.78600  1.000 329.06000 ? 8   DG  C "C2'" 1 
ATOM   7439 C  "C1'" . DG  C 3 8   ? 58.77200  35.38600  33.01500  1.000 326.39000 ? 8   DG  C "C1'" 1 
ATOM   7440 N  N9    . DG  C 3 8   ? 58.82000  36.84800  33.07000  1.000 324.88000 ? 8   DG  C N9    1 
ATOM   7441 C  C8    . DG  C 3 8   ? 59.74700  37.62900  32.44600  1.000 331.06000 ? 8   DG  C C8    1 
ATOM   7442 N  N7    . DG  C 3 8   ? 59.54900  38.90400  32.60500  1.000 330.84000 ? 8   DG  C N7    1 
ATOM   7443 C  C5    . DG  C 3 8   ? 58.39700  38.97500  33.37400  1.000 325.40000 ? 8   DG  C C5    1 
ATOM   7444 C  C6    . DG  C 3 8   ? 57.69800  40.11000  33.84700  1.000 326.78000 ? 8   DG  C C6    1 
ATOM   7445 O  O6    . DG  C 3 8   ? 57.98600  41.29100  33.70000  1.000 328.62000 ? 8   DG  C O6    1 
ATOM   7446 N  N1    . DG  C 3 8   ? 56.58300  39.75900  34.60200  1.000 332.98000 ? 8   DG  C N1    1 
ATOM   7447 C  C2    . DG  C 3 8   ? 56.18300  38.46900  34.83700  1.000 329.99000 ? 8   DG  C C2    1 
ATOM   7448 N  N2    . DG  C 3 8   ? 55.07300  38.31600  35.58400  1.000 332.26000 ? 8   DG  C N2    1 
ATOM   7449 N  N3    . DG  C 3 8   ? 56.83400  37.39900  34.39100  1.000 322.60000 ? 8   DG  C N3    1 
ATOM   7450 C  C4    . DG  C 3 8   ? 57.92200  37.72300  33.66500  1.000 323.59000 ? 8   DG  C C4    1 
ATOM   7451 P  P     . DT  C 3 9   ? 62.84000  33.14900  34.11000  1.000 361.29000 ? 9   DT  C P     1 
ATOM   7452 O  OP1   . DT  C 3 9   ? 63.43500  32.30300  33.05300  1.000 346.98000 ? 9   DT  C OP1   1 
ATOM   7453 O  OP2   . DT  C 3 9   ? 63.33700  32.95800  35.47800  1.000 345.73000 ? 9   DT  C OP2   1 
ATOM   7454 O  "O5'" . DT  C 3 9   ? 63.02700  34.70400  33.79300  1.000 346.35000 ? 9   DT  C "O5'" 1 
ATOM   7455 C  "C5'" . DT  C 3 9   ? 64.32700  35.24900  33.72900  1.000 351.29000 ? 9   DT  C "C5'" 1 
ATOM   7456 C  "C4'" . DT  C 3 9   ? 64.27600  36.72900  33.42400  1.000 359.48000 ? 9   DT  C "C4'" 1 
ATOM   7457 O  "O4'" . DT  C 3 9   ? 62.98900  37.28300  33.77100  1.000 353.48000 ? 9   DT  C "O4'" 1 
ATOM   7458 C  "C3'" . DT  C 3 9   ? 65.27900  37.57700  34.20000  1.000 356.76000 ? 9   DT  C "C3'" 1 
ATOM   7459 O  "O3'" . DT  C 3 9   ? 66.49200  37.76600  33.42300  1.000 363.72000 ? 9   DT  C "O3'" 1 
ATOM   7460 C  "C2'" . DT  C 3 9   ? 64.51000  38.90400  34.44400  1.000 351.64000 ? 9   DT  C "C2'" 1 
ATOM   7461 C  "C1'" . DT  C 3 9   ? 63.15100  38.67100  33.76400  1.000 351.32000 ? 9   DT  C "C1'" 1 
ATOM   7462 N  N1    . DT  C 3 9   ? 62.00300  39.27200  34.47300  1.000 344.63000 ? 9   DT  C N1    1 
ATOM   7463 C  C2    . DT  C 3 9   ? 61.57700  40.54000  34.13800  1.000 350.50000 ? 9   DT  C C2    1 
ATOM   7464 O  O2    . DT  C 3 9   ? 62.11400  41.23000  33.26800  1.000 358.05000 ? 9   DT  C O2    1 
ATOM   7465 N  N3    . DT  C 3 9   ? 60.48700  40.97800  34.85400  1.000 348.41000 ? 9   DT  C N3    1 
ATOM   7466 C  C4    . DT  C 3 9   ? 59.81700  40.30200  35.84900  1.000 340.48000 ? 9   DT  C C4    1 
ATOM   7467 O  O4    . DT  C 3 9   ? 58.84600  40.78000  36.43000  1.000 335.59000 ? 9   DT  C O4    1 
ATOM   7468 C  C5    . DT  C 3 9   ? 60.30600  38.96900  36.12400  1.000 335.49000 ? 9   DT  C C5    1 
ATOM   7469 C  C7    . DT  C 3 9   ? 59.65500  38.11000  37.17300  1.000 334.32000 ? 9   DT  C C7    1 
ATOM   7470 C  C6    . DT  C 3 9   ? 61.36200  38.53000  35.42900  1.000 334.76000 ? 9   DT  C C6    1 
ATOM   7471 P  P     . DA  C 3 10  ? 67.94900  37.61800  34.10200  1.000 371.50000 ? 10  DA  C P     1 
ATOM   7472 O  OP1   . DA  C 3 10  ? 68.99200  37.71800  33.05800  1.000 365.38000 ? 10  DA  C OP1   1 
ATOM   7473 O  OP2   . DA  C 3 10  ? 67.92400  36.38100  34.89800  1.000 366.83000 ? 10  DA  C OP2   1 
ATOM   7474 O  "O5'" . DA  C 3 10  ? 68.03900  38.89400  35.07500  1.000 361.80000 ? 10  DA  C "O5'" 1 
ATOM   7475 C  "C5'" . DA  C 3 10  ? 68.92100  39.99500  34.75900  1.000 370.58000 ? 10  DA  C "C5'" 1 
ATOM   7476 C  "C4'" . DA  C 3 10  ? 68.26000  41.03300  33.82500  1.000 384.66000 ? 10  DA  C "C4'" 1 
ATOM   7477 O  "O4'" . DA  C 3 10  ? 66.83500  40.77100  33.70700  1.000 380.25000 ? 10  DA  C "O4'" 1 
ATOM   7478 C  "C3'" . DA  C 3 10  ? 68.38900  42.50100  34.26900  1.000 388.55000 ? 10  DA  C "C3'" 1 
ATOM   7479 O  "O3'" . DA  C 3 10  ? 69.50400  43.16200  33.59800  1.000 405.78000 ? 10  DA  C "O3'" 1 
ATOM   7480 C  "C2'" . DA  C 3 10  ? 67.05900  43.12400  33.83400  1.000 379.49000 ? 10  DA  C "C2'" 1 
ATOM   7481 C  "C1'" . DA  C 3 10  ? 66.09200  41.95900  33.89700  1.000 369.97000 ? 10  DA  C "C1'" 1 
ATOM   7482 N  N9    . DA  C 3 10  ? 65.35200  41.83100  35.15800  1.000 363.61000 ? 10  DA  C N9    1 
ATOM   7483 C  C8    . DA  C 3 10  ? 65.71600  41.11000  36.27300  1.000 353.33000 ? 10  DA  C C8    1 
ATOM   7484 N  N7    . DA  C 3 10  ? 64.82200  41.13300  37.22400  1.000 347.11000 ? 10  DA  C N7    1 
ATOM   7485 C  C5    . DA  C 3 10  ? 63.80500  41.92100  36.70300  1.000 354.67000 ? 10  DA  C C5    1 
ATOM   7486 C  C6    . DA  C 3 10  ? 62.56500  42.33800  37.22200  1.000 353.77000 ? 10  DA  C C6    1 
ATOM   7487 N  N6    . DA  C 3 10  ? 62.12800  42.01100  38.42600  1.000 351.87000 ? 10  DA  C N6    1 
ATOM   7488 N  N1    . DA  C 3 10  ? 61.78800  43.12000  36.43900  1.000 362.68000 ? 10  DA  C N1    1 
ATOM   7489 C  C2    . DA  C 3 10  ? 62.23200  43.46500  35.21600  1.000 367.52000 ? 10  DA  C C2    1 
ATOM   7490 N  N3    . DA  C 3 10  ? 63.37600  43.13200  34.62300  1.000 366.85000 ? 10  DA  C N3    1 
ATOM   7491 C  C4    . DA  C 3 10  ? 64.11600  42.34700  35.42600  1.000 362.15000 ? 10  DA  C C4    1 
ATOM   7492 P  P     . DG  C 3 11  ? 70.84100  43.63300  34.39000  1.000 431.08000 ? 11  DG  C P     1 
ATOM   7493 O  OP1   . DG  C 3 11  ? 71.96400  42.82600  33.85800  1.000 407.10000 ? 11  DG  C OP1   1 
ATOM   7494 O  OP2   . DG  C 3 11  ? 70.58300  43.58300  35.84300  1.000 400.21000 ? 11  DG  C OP2   1 
ATOM   7495 O  "O5'" . DG  C 3 11  ? 71.08800  45.16100  33.90900  1.000 406.42000 ? 11  DG  C "O5'" 1 
ATOM   7496 C  "C5'" . DG  C 3 11  ? 70.67900  46.28000  34.71400  1.000 389.52000 ? 11  DG  C "C5'" 1 
ATOM   7497 C  "C4'" . DG  C 3 11  ? 69.19500  46.54000  34.54400  1.000 385.16000 ? 11  DG  C "C4'" 1 
ATOM   7498 O  "O4'" . DG  C 3 11  ? 68.51900  45.50200  35.22400  1.000 390.57000 ? 11  DG  C "O4'" 1 
ATOM   7499 C  "C3'" . DG  C 3 11  ? 68.67000  47.83500  35.15500  1.000 385.17000 ? 11  DG  C "C3'" 1 
ATOM   7500 O  "O3'" . DG  C 3 11  ? 68.61700  48.85200  34.17500  1.000 379.73000 ? 11  DG  C "O3'" 1 
ATOM   7501 C  "C2'" . DG  C 3 11  ? 67.27100  47.46900  35.67500  1.000 382.09000 ? 11  DG  C "C2'" 1 
ATOM   7502 C  "C1'" . DG  C 3 11  ? 67.27100  45.93900  35.63300  1.000 381.83000 ? 11  DG  C "C1'" 1 
ATOM   7503 N  N9    . DG  C 3 11  ? 66.93100  45.24300  36.89000  1.000 377.94000 ? 11  DG  C N9    1 
ATOM   7504 C  C8    . DG  C 3 11  ? 67.73500  44.41900  37.66700  1.000 370.58000 ? 11  DG  C C8    1 
ATOM   7505 N  N7    . DG  C 3 11  ? 67.09700  43.89800  38.68500  1.000 354.06000 ? 11  DG  C N7    1 
ATOM   7506 C  C5    . DG  C 3 11  ? 65.79800  44.39900  38.54500  1.000 362.54000 ? 11  DG  C C5    1 
ATOM   7507 C  C6    . DG  C 3 11  ? 64.64400  44.19800  39.33800  1.000 365.20000 ? 11  DG  C C6    1 
ATOM   7508 O  O6    . DG  C 3 11  ? 64.52500  43.51200  40.35300  1.000 360.20000 ? 11  DG  C O6    1 
ATOM   7509 N  N1    . DG  C 3 11  ? 63.53200  44.91400  38.83100  1.000 367.62000 ? 11  DG  C N1    1 
ATOM   7510 C  C2    . DG  C 3 11  ? 63.55000  45.71200  37.69700  1.000 372.70000 ? 11  DG  C C2    1 
ATOM   7511 N  N2    . DG  C 3 11  ? 62.38800  46.32000  37.34900  1.000 373.86000 ? 11  DG  C N2    1 
ATOM   7512 N  N3    . DG  C 3 11  ? 64.62100  45.88600  36.94900  1.000 374.82000 ? 11  DG  C N3    1 
ATOM   7513 C  C4    . DG  C 3 11  ? 65.69700  45.21000  37.43700  1.000 372.22000 ? 11  DG  C C4    1 
ATOM   7514 P  P     . DG  C 3 12  ? 69.90800  49.77200  33.89400  1.000 382.05000 ? 12  DG  C P     1 
ATOM   7515 O  OP1   . DG  C 3 12  ? 69.77400  50.34300  32.54000  1.000 387.39000 ? 12  DG  C OP1   1 
ATOM   7516 O  OP2   . DG  C 3 12  ? 71.15900  49.11100  34.29400  1.000 378.91000 ? 12  DG  C OP2   1 
ATOM   7517 O  "O5'" . DG  C 3 12  ? 69.74100  50.98100  34.89400  1.000 382.15000 ? 12  DG  C "O5'" 1 
ATOM   7518 C  "C5'" . DG  C 3 12  ? 69.15900  52.15800  34.43400  1.000 382.35000 ? 12  DG  C "C5'" 1 
ATOM   7519 C  "C4'" . DG  C 3 12  ? 67.72600  52.26200  34.90000  1.000 380.05000 ? 12  DG  C "C4'" 1 
ATOM   7520 O  "O4'" . DG  C 3 12  ? 67.29200  51.00800  35.52000  1.000 385.44000 ? 12  DG  C "O4'" 1 
ATOM   7521 C  "C3'" . DG  C 3 12  ? 67.50200  53.33100  35.94900  1.000 379.81000 ? 12  DG  C "C3'" 1 
ATOM   7522 O  "O3'" . DG  C 3 12  ? 66.22100  53.84800  35.79400  1.000 386.01000 ? 12  DG  C "O3'" 1 
ATOM   7523 C  "C2'" . DG  C 3 12  ? 67.61500  52.53900  37.23900  1.000 378.64000 ? 12  DG  C "C2'" 1 
ATOM   7524 C  "C1'" . DG  C 3 12  ? 66.88400  51.26800  36.85700  1.000 378.21000 ? 12  DG  C "C1'" 1 
ATOM   7525 N  N9    . DG  C 3 12  ? 67.25300  50.13400  37.71600  1.000 380.20000 ? 12  DG  C N9    1 
ATOM   7526 C  C8    . DG  C 3 12  ? 68.51100  49.60600  37.86000  1.000 385.68000 ? 12  DG  C C8    1 
ATOM   7527 N  N7    . DG  C 3 12  ? 68.57600  48.60900  38.70000  1.000 382.98000 ? 12  DG  C N7    1 
ATOM   7528 C  C5    . DG  C 3 12  ? 67.27900  48.47800  39.17200  1.000 374.15000 ? 12  DG  C C5    1 
ATOM   7529 C  C6    . DG  C 3 12  ? 66.76500  47.56500  40.10900  1.000 366.32000 ? 12  DG  C C6    1 
ATOM   7530 O  O6    . DG  C 3 12  ? 67.37700  46.67000  40.71200  1.000 361.72000 ? 12  DG  C O6    1 
ATOM   7531 N  N1    . DG  C 3 12  ? 65.39600  47.75500  40.32300  1.000 365.75000 ? 12  DG  C N1    1 
ATOM   7532 C  C2    . DG  C 3 12  ? 64.62700  48.70400  39.69000  1.000 360.45000 ? 12  DG  C C2    1 
ATOM   7533 N  N2    . DG  C 3 12  ? 63.32700  48.74200  40.03700  1.000 355.59000 ? 12  DG  C N2    1 
ATOM   7534 N  N3    . DG  C 3 12  ? 65.10100  49.58200  38.80200  1.000 365.11000 ? 12  DG  C N3    1 
ATOM   7535 C  C4    . DG  C 3 12  ? 66.43600  49.40900  38.58900  1.000 374.67000 ? 12  DG  C C4    1 
ATOM   7536 P  P     . DT  C 3 13  ? 65.72200  55.09200  36.67500  1.000 403.04000 ? 13  DT  C P     1 
ATOM   7537 O  OP1   . DT  C 3 13  ? 65.98300  56.30200  35.87600  1.000 408.14000 ? 13  DT  C OP1   1 
ATOM   7538 O  OP2   . DT  C 3 13  ? 66.26400  55.02000  38.05500  1.000 386.25000 ? 13  DT  C OP2   1 
ATOM   7539 O  "O5'" . DT  C 3 13  ? 64.14100  54.88100  36.71000  1.000 385.64000 ? 13  DT  C "O5'" 1 
ATOM   7540 C  "C5'" . DT  C 3 13  ? 63.33700  55.69500  37.54500  1.000 379.30000 ? 13  DT  C "C5'" 1 
ATOM   7541 C  "C4'" . DT  C 3 13  ? 62.97100  54.95200  38.81800  1.000 383.76000 ? 13  DT  C "C4'" 1 
ATOM   7542 O  "O4'" . DT  C 3 13  ? 63.85900  53.79800  38.99200  1.000 388.37000 ? 13  DT  C "O4'" 1 
ATOM   7543 C  "C3'" . DT  C 3 13  ? 63.06500  55.78000  40.13400  1.000 388.96000 ? 13  DT  C "C3'" 1 
ATOM   7544 O  "O3'" . DT  C 3 13  ? 61.71300  55.96200  40.76400  1.000 391.09000 ? 13  DT  C "O3'" 1 
ATOM   7545 C  "C2'" . DT  C 3 13  ? 64.03300  54.95300  41.00900  1.000 392.11000 ? 13  DT  C "C2'" 1 
ATOM   7546 C  "C1'" . DT  C 3 13  ? 63.96900  53.55400  40.37700  1.000 390.02000 ? 13  DT  C "C1'" 1 
ATOM   7547 N  N1    . DT  C 3 13  ? 65.20300  52.67400  40.69200  1.000 382.57000 ? 13  DT  C N1    1 
ATOM   7548 C  C2    . DT  C 3 13  ? 65.02800  51.37700  41.16200  1.000 374.38000 ? 13  DT  C C2    1 
ATOM   7549 O  O2    . DT  C 3 13  ? 63.92300  50.84100  41.28900  1.000 364.27000 ? 13  DT  C O2    1 
ATOM   7550 N  N3    . DT  C 3 13  ? 66.20300  50.70400  41.44200  1.000 377.55000 ? 13  DT  C N3    1 
ATOM   7551 C  C4    . DT  C 3 13  ? 67.49400  51.19200  41.33900  1.000 374.90000 ? 13  DT  C C4    1 
ATOM   7552 O  O4    . DT  C 3 13  ? 68.47700  50.51800  41.61900  1.000 370.10000 ? 13  DT  C O4    1 
ATOM   7553 C  C5    . DT  C 3 13  ? 67.60700  52.56000  40.87100  1.000 373.98000 ? 13  DT  C C5    1 
ATOM   7554 C  C7    . DT  C 3 13  ? 68.95800  53.21200  40.70900  1.000 358.46000 ? 13  DT  C C7    1 
ATOM   7555 C  C6    . DT  C 3 13  ? 66.47000  53.22700  40.58700  1.000 379.20000 ? 13  DT  C C6    1 
ATOM   7556 P  P     . DT  C 3 14  ? 61.51100  56.55200  42.26800  1.000 380.93000 ? 14  DT  C P     1 
ATOM   7557 O  OP1   . DT  C 3 14  ? 60.09400  56.86900  42.56400  1.000 366.98000 ? 14  DT  C OP1   1 
ATOM   7558 O  OP2   . DT  C 3 14  ? 62.52000  57.58400  42.53600  1.000 378.95000 ? 14  DT  C OP2   1 
ATOM   7559 O  "O5'" . DT  C 3 14  ? 61.89500  55.33500  43.20300  1.000 374.15000 ? 14  DT  C "O5'" 1 
ATOM   7560 C  "C5'" . DT  C 3 14  ? 61.21500  54.09300  43.10400  1.000 370.62000 ? 14  DT  C "C5'" 1 
ATOM   7561 C  "C4'" . DT  C 3 14  ? 61.26300  53.38100  44.43600  1.000 364.40000 ? 14  DT  C "C4'" 1 
ATOM   7562 O  "O4'" . DT  C 3 14  ? 62.51700  52.65700  44.54500  1.000 359.53000 ? 14  DT  C "O4'" 1 
ATOM   7563 C  "C3'" . DT  C 3 14  ? 61.24900  54.33000  45.63400  1.000 370.71000 ? 14  DT  C "C3'" 1 
ATOM   7564 O  "O3'" . DT  C 3 14  ? 60.71900  53.70100  46.78200  1.000 385.43000 ? 14  DT  C "O3'" 1 
ATOM   7565 C  "C2'" . DT  C 3 14  ? 62.72100  54.60800  45.83500  1.000 365.81000 ? 14  DT  C "C2'" 1 
ATOM   7566 C  "C1'" . DT  C 3 14  ? 63.29800  53.22800  45.58600  1.000 362.28000 ? 14  DT  C "C1'" 1 
ATOM   7567 N  N1    . DT  C 3 14  ? 64.69500  53.28300  45.16400  1.000 362.64000 ? 14  DT  C N1    1 
ATOM   7568 C  C2    . DT  C 3 14  ? 65.41100  52.12200  45.07300  1.000 365.99000 ? 14  DT  C C2    1 
ATOM   7569 O  O2    . DT  C 3 14  ? 64.93600  51.02500  45.31400  1.000 363.99000 ? 14  DT  C O2    1 
ATOM   7570 N  N3    . DT  C 3 14  ? 66.71400  52.28600  44.67700  1.000 371.04000 ? 14  DT  C N3    1 
ATOM   7571 C  C4    . DT  C 3 14  ? 67.36000  53.47600  44.38100  1.000 371.38000 ? 14  DT  C C4    1 
ATOM   7572 O  O4    . DT  C 3 14  ? 68.54200  53.51400  44.02900  1.000 375.77000 ? 14  DT  C O4    1 
ATOM   7573 C  C5    . DT  C 3 14  ? 66.54000  54.66200  44.51000  1.000 368.23000 ? 14  DT  C C5    1 
ATOM   7574 C  C7    . DT  C 3 14  ? 67.11000  56.01400  44.21500  1.000 375.57000 ? 14  DT  C C7    1 
ATOM   7575 C  C6    . DT  C 3 14  ? 65.26700  54.50900  44.89700  1.000 364.55000 ? 14  DT  C C6    1 
ATOM   7576 P  P     . DG  C 3 15  ? 60.05700  54.59600  47.95000  1.000 395.54000 ? 15  DG  C P     1 
ATOM   7577 O  OP1   . DG  C 3 15  ? 58.81500  55.11400  47.33200  1.000 397.37000 ? 15  DG  C OP1   1 
ATOM   7578 O  OP2   . DG  C 3 15  ? 61.01600  55.58200  48.50400  1.000 375.04000 ? 15  DG  C OP2   1 
ATOM   7579 O  "O5'" . DG  C 3 15  ? 59.72600  53.52900  49.11300  1.000 372.32000 ? 15  DG  C "O5'" 1 
ATOM   7580 C  "C5'" . DG  C 3 15  ? 59.88100  52.11200  48.88600  1.000 364.77000 ? 15  DG  C "C5'" 1 
ATOM   7581 C  "C4'" . DG  C 3 15  ? 60.77000  51.47500  49.94800  1.000 356.47000 ? 15  DG  C "C4'" 1 
ATOM   7582 O  "O4'" . DG  C 3 15  ? 62.14100  51.43400  49.44100  1.000 358.03000 ? 15  DG  C "O4'" 1 
ATOM   7583 C  "C3'" . DG  C 3 15  ? 60.83000  52.23700  51.29700  1.000 360.15000 ? 15  DG  C "C3'" 1 
ATOM   7584 O  "O3'" . DG  C 3 15  ? 60.97400  51.31600  52.48100  1.000 382.57000 ? 15  DG  C "O3'" 1 
ATOM   7585 C  "C2'" . DG  C 3 15  ? 62.04600  53.09600  51.09800  1.000 356.27000 ? 15  DG  C "C2'" 1 
ATOM   7586 C  "C1'" . DG  C 3 15  ? 62.96600  52.15000  50.33400  1.000 361.31000 ? 15  DG  C "C1'" 1 
ATOM   7587 N  N9    . DG  C 3 15  ? 64.02000  52.89400  49.62100  1.000 364.32000 ? 15  DG  C N9    1 
ATOM   7588 C  C8    . DG  C 3 15  ? 63.84300  54.04700  48.89500  1.000 364.64000 ? 15  DG  C C8    1 
ATOM   7589 N  N7    . DG  C 3 15  ? 64.96500  54.55000  48.44200  1.000 364.74000 ? 15  DG  C N7    1 
ATOM   7590 C  C5    . DG  C 3 15  ? 65.94800  53.70100  48.94200  1.000 362.50000 ? 15  DG  C C5    1 
ATOM   7591 C  C6    . DG  C 3 15  ? 67.35700  53.75200  48.78700  1.000 360.53000 ? 15  DG  C C6    1 
ATOM   7592 O  O6    . DG  C 3 15  ? 68.03600  54.57400  48.16300  1.000 353.89000 ? 15  DG  C O6    1 
ATOM   7593 N  N1    . DG  C 3 15  ? 67.98400  52.71100  49.45500  1.000 360.81000 ? 15  DG  C N1    1 
ATOM   7594 C  C2    . DG  C 3 15  ? 67.34500  51.74500  50.18000  1.000 357.34000 ? 15  DG  C C2    1 
ATOM   7595 N  N2    . DG  C 3 15  ? 68.14000  50.80200  50.73200  1.000 349.00000 ? 15  DG  C N2    1 
ATOM   7596 N  N3    . DG  C 3 15  ? 66.02600  51.66900  50.32800  1.000 360.20000 ? 15  DG  C N3    1 
ATOM   7597 C  C4    . DG  C 3 15  ? 65.39000  52.68700  49.68800  1.000 362.31000 ? 15  DG  C C4    1 
ATOM   7598 P  P     . DT  C 3 16  ? 61.30400  51.83000  54.00600  1.000 374.62000 ? 16  DT  C P     1 
ATOM   7599 O  OP1   . DT  C 3 16  ? 60.44300  51.16800  55.02500  1.000 350.29000 ? 16  DT  C OP1   1 
ATOM   7600 O  OP2   . DT  C 3 16  ? 61.49200  53.29200  54.05700  1.000 363.07000 ? 16  DT  C OP2   1 
ATOM   7601 O  "O5'" . DT  C 3 16  ? 62.71000  51.15700  54.32400  1.000 356.33000 ? 16  DT  C "O5'" 1 
ATOM   7602 C  "C5'" . DT  C 3 16  ? 62.87800  49.77600  54.09600  1.000 365.51000 ? 16  DT  C "C5'" 1 
ATOM   7603 C  "C4'" . DT  C 3 16  ? 64.27300  49.32100  54.47600  1.000 367.20000 ? 16  DT  C "C4'" 1 
ATOM   7604 O  "O4'" . DT  C 3 16  ? 65.24000  49.95500  53.57300  1.000 381.65000 ? 16  DT  C "O4'" 1 
ATOM   7605 C  "C3'" . DT  C 3 16  ? 64.74300  49.62000  55.93700  1.000 343.25000 ? 16  DT  C "C3'" 1 
ATOM   7606 O  "O3'" . DT  C 3 16  ? 65.53300  48.42100  56.46700  1.000 351.06000 ? 16  DT  C "O3'" 1 
ATOM   7607 C  "C2'" . DT  C 3 16  ? 65.61700  50.86300  55.71600  1.000 344.70000 ? 16  DT  C "C2'" 1 
ATOM   7608 C  "C1'" . DT  C 3 16  ? 66.25600  50.57400  54.33700  1.000 366.51000 ? 16  DT  C "C1'" 1 
ATOM   7609 N  N1    . DT  C 3 16  ? 66.77300  51.83100  53.59600  1.000 359.61000 ? 16  DT  C N1    1 
ATOM   7610 C  C2    . DT  C 3 16  ? 68.10200  51.89600  53.16800  1.000 353.93000 ? 16  DT  C C2    1 
ATOM   7611 O  O2    . DT  C 3 16  ? 68.90100  50.95800  53.25400  1.000 355.25000 ? 16  DT  C O2    1 
ATOM   7612 N  N3    . DT  C 3 16  ? 68.44200  53.07100  52.52900  1.000 346.77000 ? 16  DT  C N3    1 
ATOM   7613 C  C4    . DT  C 3 16  ? 67.63900  54.16900  52.32100  1.000 344.95000 ? 16  DT  C C4    1 
ATOM   7614 O  O4    . DT  C 3 16  ? 68.04100  55.17500  51.75900  1.000 344.03000 ? 16  DT  C O4    1 
ATOM   7615 C  C5    . DT  C 3 16  ? 66.27800  54.05300  52.81700  1.000 345.69000 ? 16  DT  C C5    1 
ATOM   7616 C  C7    . DT  C 3 16  ? 65.29300  55.18700  52.65000  1.000 342.21000 ? 16  DT  C C7    1 
ATOM   7617 C  C6    . DT  C 3 16  ? 65.92100  52.90600  53.42600  1.000 351.17000 ? 16  DT  C C6    1 
ATOM   7618 P  P     . DA  C 3 17  ? 66.00900  48.15300  58.02100  1.000 307.35000 ? 17  DA  C P     1 
ATOM   7619 O  OP1   . DA  C 3 17  ? 65.05300  47.26900  58.70700  1.000 317.58000 ? 17  DA  C OP1   1 
ATOM   7620 O  OP2   . DA  C 3 17  ? 66.51600  49.34200  58.71700  1.000 303.73000 ? 17  DA  C OP2   1 
ATOM   7621 O  "O5'" . DA  C 3 17  ? 67.31900  47.22000  57.85400  1.000 298.36000 ? 17  DA  C "O5'" 1 
ATOM   7622 C  "C5'" . DA  C 3 17  ? 68.45700  47.37700  58.72500  1.000 299.36000 ? 17  DA  C "C5'" 1 
ATOM   7623 C  "C4'" . DA  C 3 17  ? 69.62800  48.02100  57.97200  1.000 300.02000 ? 17  DA  C "C4'" 1 
ATOM   7624 O  "O4'" . DA  C 3 17  ? 69.18500  49.18700  57.25300  1.000 314.79000 ? 17  DA  C "O4'" 1 
ATOM   7625 C  "C3'" . DA  C 3 17  ? 70.77000  48.53100  58.82800  1.000 302.26000 ? 17  DA  C "C3'" 1 
ATOM   7626 O  "O3'" . DA  C 3 17  ? 71.84200  47.65500  58.77100  1.000 295.27000 ? 17  DA  C "O3'" 1 
ATOM   7627 C  "C2'" . DA  C 3 17  ? 71.14000  49.90200  58.22900  1.000 303.20000 ? 17  DA  C "C2'" 1 
ATOM   7628 C  "C1'" . DA  C 3 17  ? 70.32600  49.97700  56.96000  1.000 322.64000 ? 17  DA  C "C1'" 1 
ATOM   7629 N  N9    . DA  C 3 17  ? 69.88400  51.35100  56.48400  1.000 333.74000 ? 17  DA  C N9    1 
ATOM   7630 C  C8    . DA  C 3 17  ? 68.62700  51.87000  56.63900  1.000 330.57000 ? 17  DA  C C8    1 
ATOM   7631 N  N7    . DA  C 3 17  ? 68.44200  53.05800  56.08200  1.000 333.33000 ? 17  DA  C N7    1 
ATOM   7632 C  C5    . DA  C 3 17  ? 69.67000  53.36000  55.48700  1.000 339.92000 ? 17  DA  C C5    1 
ATOM   7633 C  C6    . DA  C 3 17  ? 70.12400  54.48900  54.71600  1.000 342.75000 ? 17  DA  C C6    1 
ATOM   7634 N  N6    . DA  C 3 17  ? 69.37100  55.57300  54.43900  1.000 340.94000 ? 17  DA  C N6    1 
ATOM   7635 N  N1    . DA  C 3 17  ? 71.40700  54.47600  54.27700  1.000 343.92000 ? 17  DA  C N1    1 
ATOM   7636 C  C2    . DA  C 3 17  ? 72.18400  53.42300  54.58300  1.000 340.19000 ? 17  DA  C C2    1 
ATOM   7637 N  N3    . DA  C 3 17  ? 71.87000  52.28500  55.25300  1.000 343.55000 ? 17  DA  C N3    1 
ATOM   7638 C  C4    . DA  C 3 17  ? 70.58600  52.31700  55.70100  1.000 341.83000 ? 17  DA  C C4    1 
ATOM   7639 P  P     . DT  C 3 18  ? 72.79200  47.53600  60.05800  1.000 300.22000 ? 18  DT  C P     1 
ATOM   7640 O  OP1   . DT  C 3 18  ? 73.50100  46.24400  60.17900  1.000 299.99000 ? 18  DT  C OP1   1 
ATOM   7641 O  OP2   . DT  C 3 18  ? 71.95500  48.02500  61.15200  1.000 306.77000 ? 18  DT  C OP2   1 
ATOM   7642 O  "O5'" . DT  C 3 18  ? 73.93000  48.58000  59.76700  1.000 298.55000 ? 18  DT  C "O5'" 1 
ATOM   7643 C  "C5'" . DT  C 3 18  ? 74.72700  48.33200  58.69300  1.000 313.38000 ? 18  DT  C "C5'" 1 
ATOM   7644 C  "C4'" . DT  C 3 18  ? 75.38800  49.58700  58.20800  1.000 329.15000 ? 18  DT  C "C4'" 1 
ATOM   7645 O  "O4'" . DT  C 3 18  ? 74.40300  50.56300  57.85900  1.000 332.97000 ? 18  DT  C "O4'" 1 
ATOM   7646 C  "C3'" . DT  C 3 18  ? 76.30600  50.25400  59.21700  1.000 324.10000 ? 18  DT  C "C3'" 1 
ATOM   7647 O  "O3'" . DT  C 3 18  ? 77.61600  50.20400  58.70400  1.000 332.73000 ? 18  DT  C "O3'" 1 
ATOM   7648 C  "C2'" . DT  C 3 18  ? 75.77400  51.69600  59.33600  1.000 325.78000 ? 18  DT  C "C2'" 1 
ATOM   7649 C  "C1'" . DT  C 3 18  ? 74.95200  51.83800  58.06900  1.000 332.08000 ? 18  DT  C "C1'" 1 
ATOM   7650 N  N1    . DT  C 3 18  ? 73.81200  52.73200  58.17400  1.000 330.51000 ? 18  DT  C N1    1 
ATOM   7651 C  C2    . DT  C 3 18  ? 73.73300  53.88300  57.41000  1.000 339.35000 ? 18  DT  C C2    1 
ATOM   7652 O  O2    . DT  C 3 18  ? 74.62200  54.27400  56.65600  1.000 340.92000 ? 18  DT  C O2    1 
ATOM   7653 N  N3    . DT  C 3 18  ? 72.55600  54.58000  57.57400  1.000 340.56000 ? 18  DT  C N3    1 
ATOM   7654 C  C4    . DT  C 3 18  ? 71.48500  54.23500  58.38100  1.000 332.38000 ? 18  DT  C C4    1 
ATOM   7655 O  O4    . DT  C 3 18  ? 70.46600  54.92200  58.47300  1.000 330.93000 ? 18  DT  C O4    1 
ATOM   7656 C  C5    . DT  C 3 18  ? 71.65100  53.02000  59.11200  1.000 319.79000 ? 18  DT  C C5    1 
ATOM   7657 C  C7    . DT  C 3 18  ? 70.56900  52.55300  60.02000  1.000 315.60000 ? 18  DT  C C7    1 
ATOM   7658 C  C6    . DT  C 3 18  ? 72.78900  52.34600  58.97500  1.000 318.57000 ? 18  DT  C C6    1 
ATOM   7659 P  P     . DA  C 3 19  ? 78.86500  50.34600  59.69200  1.000 317.37000 ? 19  DA  C P     1 
ATOM   7660 O  OP1   . DA  C 3 19  ? 79.97500  49.43800  59.34200  1.000 326.41000 ? 19  DA  C OP1   1 
ATOM   7661 O  OP2   . DA  C 3 19  ? 78.26200  50.23600  61.03200  1.000 319.31000 ? 19  DA  C OP2   1 
ATOM   7662 O  "O5'" . DA  C 3 19  ? 79.36800  51.82200  59.37700  1.000 321.58000 ? 19  DA  C "O5'" 1 
ATOM   7663 C  "C5'" . DA  C 3 19  ? 79.13600  52.38400  58.08400  1.000 335.33000 ? 19  DA  C "C5'" 1 
ATOM   7664 C  "C4'" . DA  C 3 19  ? 79.27200  53.88400  58.16900  1.000 347.73000 ? 19  DA  C "C4'" 1 
ATOM   7665 O  "O4'" . DA  C 3 19  ? 77.94200  54.46800  58.21000  1.000 355.86000 ? 19  DA  C "O4'" 1 
ATOM   7666 C  "C3'" . DA  C 3 19  ? 79.98100  54.35000  59.44100  1.000 345.33000 ? 19  DA  C "C3'" 1 
ATOM   7667 O  "O3'" . DA  C 3 19  ? 80.88900  55.42100  59.18000  1.000 359.41000 ? 19  DA  C "O3'" 1 
ATOM   7668 C  "C2'" . DA  C 3 19  ? 78.82400  54.77700  60.33300  1.000 340.21000 ? 19  DA  C "C2'" 1 
ATOM   7669 C  "C1'" . DA  C 3 19  ? 77.85900  55.34300  59.31700  1.000 350.34000 ? 19  DA  C "C1'" 1 
ATOM   7670 N  N9    . DA  C 3 19  ? 76.45400  55.39900  59.78700  1.000 343.77000 ? 19  DA  C N9    1 
ATOM   7671 C  C8    . DA  C 3 19  ? 75.89000  54.61900  60.76500  1.000 329.95000 ? 19  DA  C C8    1 
ATOM   7672 N  N7    . DA  C 3 19  ? 74.62600  54.89400  60.99000  1.000 331.25000 ? 19  DA  C N7    1 
ATOM   7673 C  C5    . DA  C 3 19  ? 74.34300  55.93700  60.09600  1.000 347.86000 ? 19  DA  C C5    1 
ATOM   7674 C  C6    . DA  C 3 19  ? 73.15600  56.69400  59.83300  1.000 354.83000 ? 19  DA  C C6    1 
ATOM   7675 N  N6    . DA  C 3 19  ? 71.98900  56.50300  60.46400  1.000 350.20000 ? 19  DA  C N6    1 
ATOM   7676 N  N1    . DA  C 3 19  ? 73.22500  57.66400  58.86700  1.000 358.26000 ? 19  DA  C N1    1 
ATOM   7677 C  C2    . DA  C 3 19  ? 74.39600  57.86400  58.22400  1.000 357.73000 ? 19  DA  C C2    1 
ATOM   7678 N  N3    . DA  C 3 19  ? 75.55300  57.21600  58.38600  1.000 358.35000 ? 19  DA  C N3    1 
ATOM   7679 C  C4    . DA  C 3 19  ? 75.46000  56.26000  59.34500  1.000 351.94000 ? 19  DA  C C4    1 
ATOM   7680 P  P     . DG  C 3 20  ? 82.19300  55.62100  60.10500  1.000 340.18000 ? 20  DG  C P     1 
ATOM   7681 O  OP1   . DG  C 3 20  ? 83.33000  54.91600  59.47600  1.000 342.52000 ? 20  DG  C OP1   1 
ATOM   7682 O  OP2   . DG  C 3 20  ? 81.76400  55.22900  61.45400  1.000 341.32000 ? 20  DG  C OP2   1 
ATOM   7683 O  "O5'" . DG  C 3 20  ? 82.41000  57.20400  60.14200  1.000 344.07000 ? 20  DG  C "O5'" 1 
ATOM   7684 C  "C5'" . DG  C 3 20  ? 81.99700  57.99200  59.04200  1.000 367.67000 ? 20  DG  C "C5'" 1 
ATOM   7685 C  "C4'" . DG  C 3 20  ? 81.17600  59.18700  59.49000  1.000 375.86000 ? 20  DG  C "C4'" 1 
ATOM   7686 O  "O4'" . DG  C 3 20  ? 79.85500  58.73600  59.86300  1.000 376.22000 ? 20  DG  C "O4'" 1 
ATOM   7687 C  "C3'" . DG  C 3 20  ? 81.72400  59.97000  60.71100  1.000 365.31000 ? 20  DG  C "C3'" 1 
ATOM   7688 O  "O3'" . DG  C 3 20  ? 81.91800  61.39900  60.37600  1.000 385.01000 ? 20  DG  C "O3'" 1 
ATOM   7689 C  "C2'" . DG  C 3 20  ? 80.63400  59.76800  61.76900  1.000 361.30000 ? 20  DG  C "C2'" 1 
ATOM   7690 C  "C1'" . DG  C 3 20  ? 79.41100  59.55400  60.89500  1.000 365.40000 ? 20  DG  C "C1'" 1 
ATOM   7691 N  N9    . DG  C 3 20  ? 78.31500  58.88900  61.56800  1.000 354.58000 ? 20  DG  C N9    1 
ATOM   7692 C  C8    . DG  C 3 20  ? 78.32600  57.64700  62.13000  1.000 354.28000 ? 20  DG  C C8    1 
ATOM   7693 N  N7    . DG  C 3 20  ? 77.18800  57.30500  62.66600  1.000 353.67000 ? 20  DG  C N7    1 
ATOM   7694 C  C5    . DG  C 3 20  ? 76.37200  58.40200  62.44000  1.000 353.21000 ? 20  DG  C C5    1 
ATOM   7695 C  C6    . DG  C 3 20  ? 75.02100  58.61600  62.79600  1.000 358.80000 ? 20  DG  C C6    1 
ATOM   7696 O  O6    . DG  C 3 20  ? 74.25400  57.85100  63.40600  1.000 350.45000 ? 20  DG  C O6    1 
ATOM   7697 N  N1    . DG  C 3 20  ? 74.56900  59.87500  62.37100  1.000 371.40000 ? 20  DG  C N1    1 
ATOM   7698 C  C2    . DG  C 3 20  ? 75.33300  60.79600  61.68600  1.000 371.88000 ? 20  DG  C C2    1 
ATOM   7699 N  N2    . DG  C 3 20  ? 74.72600  61.95300  61.35300  1.000 367.79000 ? 20  DG  C N2    1 
ATOM   7700 N  N3    . DG  C 3 20  ? 76.60100  60.59900  61.35000  1.000 372.31000 ? 20  DG  C N3    1 
ATOM   7701 C  C4    . DG  C 3 20  ? 77.05100  59.38700  61.75900  1.000 361.23000 ? 20  DG  C C4    1 
ATOM   7702 P  P     . DT  C 3 21  ? 82.27800  62.50500  61.50600  1.000 373.04000 ? 21  DT  C P     1 
ATOM   7703 O  OP1   . DT  C 3 21  ? 83.19200  63.53500  60.96600  1.000 375.47000 ? 21  DT  C OP1   1 
ATOM   7704 O  OP2   . DT  C 3 21  ? 82.66300  61.79200  62.73300  1.000 360.29000 ? 21  DT  C OP2   1 
ATOM   7705 O  "O5'" . DT  C 3 21  ? 80.90100  63.29500  61.74200  1.000 381.68000 ? 21  DT  C "O5'" 1 
ATOM   7706 C  "C5'" . DT  C 3 21  ? 80.46600  64.28600  60.78100  1.000 385.74000 ? 21  DT  C "C5'" 1 
ATOM   7707 C  "C4'" . DT  C 3 21  ? 79.13100  64.90800  61.18200  1.000 387.12000 ? 21  DT  C "C4'" 1 
ATOM   7708 O  "O4'" . DT  C 3 21  ? 78.25800  63.89100  61.76600  1.000 391.54000 ? 21  DT  C "O4'" 1 
ATOM   7709 C  "C3'" . DT  C 3 21  ? 79.22100  66.03800  62.21300  1.000 390.27000 ? 21  DT  C "C3'" 1 
ATOM   7710 O  "O3'" . DT  C 3 21  ? 78.43400  67.15700  61.78100  1.000 394.39000 ? 21  DT  C "O3'" 1 
ATOM   7711 C  "C2'" . DT  C 3 21  ? 78.66900  65.40000  63.50500  1.000 392.71000 ? 21  DT  C "C2'" 1 
ATOM   7712 C  "C1'" . DT  C 3 21  ? 77.66400  64.39600  62.95000  1.000 390.14000 ? 21  DT  C "C1'" 1 
ATOM   7713 N  N1    . DT  C 3 21  ? 77.29800  63.21900  63.91600  1.000 388.54000 ? 21  DT  C N1    1 
ATOM   7714 C  C2    . DT  C 3 21  ? 76.08900  63.24700  64.61200  1.000 382.73000 ? 21  DT  C C2    1 
ATOM   7715 O  O2    . DT  C 3 21  ? 75.27600  64.16100  64.51800  1.000 380.40000 ? 21  DT  C O2    1 
ATOM   7716 N  N3    . DT  C 3 21  ? 75.86600  62.15400  65.43200  1.000 379.39000 ? 21  DT  C N3    1 
ATOM   7717 C  C4    . DT  C 3 21  ? 76.69900  61.05600  65.62900  1.000 369.64000 ? 21  DT  C C4    1 
ATOM   7718 O  O4    . DT  C 3 21  ? 76.40400  60.12500  66.39200  1.000 358.67000 ? 21  DT  C O4    1 
ATOM   7719 C  C5    . DT  C 3 21  ? 77.94200  61.08500  64.87600  1.000 371.64000 ? 21  DT  C C5    1 
ATOM   7720 C  C7    . DT  C 3 21  ? 78.92700  59.95600  65.00400  1.000 359.68000 ? 21  DT  C C7    1 
ATOM   7721 C  C6    . DT  C 3 21  ? 78.17800  62.15100  64.06900  1.000 379.54000 ? 21  DT  C C6    1 
ATOM   7722 O  "O5'" . DA  D 4 2   ? 72.81400  65.71400  54.13800  1.000 379.14000 ? 3   DA  D "O5'" 1 
ATOM   7723 C  "C5'" . DA  D 4 2   ? 72.97000  64.55000  53.28500  1.000 380.04000 ? 3   DA  D "C5'" 1 
ATOM   7724 C  "C4'" . DA  D 4 2   ? 74.11800  63.64200  53.75700  1.000 382.36000 ? 3   DA  D "C4'" 1 
ATOM   7725 O  "O4'" . DA  D 4 2   ? 73.65600  62.80500  54.83300  1.000 372.47000 ? 3   DA  D "O4'" 1 
ATOM   7726 C  "C3'" . DA  D 4 2   ? 74.63900  62.65700  52.71300  1.000 388.74000 ? 3   DA  D "C3'" 1 
ATOM   7727 O  "O3'" . DA  D 4 2   ? 75.74400  63.22800  51.97800  1.000 405.63000 ? 3   DA  D "O3'" 1 
ATOM   7728 C  "C2'" . DA  D 4 2   ? 75.10300  61.44700  53.54900  1.000 373.15000 ? 3   DA  D "C2'" 1 
ATOM   7729 C  "C1'" . DA  D 4 2   ? 74.44700  61.64300  54.91500  1.000 367.36000 ? 3   DA  D "C1'" 1 
ATOM   7730 N  N9    . DA  D 4 2   ? 73.55000  60.56300  55.26100  1.000 363.25000 ? 3   DA  D N9    1 
ATOM   7731 C  C8    . DA  D 4 2   ? 72.25900  60.70100  55.63500  1.000 361.02000 ? 3   DA  D C8    1 
ATOM   7732 N  N7    . DA  D 4 2   ? 71.64600  59.58500  55.86800  1.000 356.15000 ? 3   DA  D N7    1 
ATOM   7733 C  C5    . DA  D 4 2   ? 72.58500  58.62900  55.56900  1.000 361.62000 ? 3   DA  D C5    1 
ATOM   7734 C  C6    . DA  D 4 2   ? 72.53900  57.23000  55.59900  1.000 366.34000 ? 3   DA  D C6    1 
ATOM   7735 N  N6    . DA  D 4 2   ? 71.46000  56.55100  55.98000  1.000 368.78000 ? 3   DA  D N6    1 
ATOM   7736 N  N1    . DA  D 4 2   ? 73.66100  56.55900  55.25700  1.000 362.66000 ? 3   DA  D N1    1 
ATOM   7737 C  C2    . DA  D 4 2   ? 74.74400  57.24700  54.89200  1.000 363.72000 ? 3   DA  D C2    1 
ATOM   7738 N  N3    . DA  D 4 2   ? 74.90400  58.56200  54.82900  1.000 365.07000 ? 3   DA  D N3    1 
ATOM   7739 C  C4    . DA  D 4 2   ? 73.77300  59.20500  55.18300  1.000 363.00000 ? 3   DA  D C4    1 
ATOM   7740 P  P     . DT  D 4 3   ? 75.70900  63.38600  50.36500  1.000 428.24000 ? 4   DT  D P     1 
ATOM   7741 O  OP1   . DT  D 4 3   ? 76.78100  64.34400  50.02300  1.000 417.15000 ? 4   DT  D OP1   1 
ATOM   7742 O  OP2   . DT  D 4 3   ? 74.31800  63.60900  49.91100  1.000 412.86000 ? 4   DT  D OP2   1 
ATOM   7743 O  "O5'" . DT  D 4 3   ? 76.19400  61.97900  49.77900  1.000 401.79000 ? 4   DT  D "O5'" 1 
ATOM   7744 C  "C5'" . DT  D 4 3   ? 75.41800  60.81700  49.97800  1.000 398.18000 ? 4   DT  D "C5'" 1 
ATOM   7745 C  "C4'" . DT  D 4 3   ? 76.27200  59.70300  50.56300  1.000 390.16000 ? 4   DT  D "C4'" 1 
ATOM   7746 O  "O4'" . DT  D 4 3   ? 75.65300  59.14700  51.76800  1.000 385.87000 ? 4   DT  D "O4'" 1 
ATOM   7747 C  "C3'" . DT  D 4 3   ? 76.48800  58.52300  49.63900  1.000 388.95000 ? 4   DT  D "C3'" 1 
ATOM   7748 O  "O3'" . DT  D 4 3   ? 77.80600  57.96900  49.87700  1.000 379.73000 ? 4   DT  D "O3'" 1 
ATOM   7749 C  "C2'" . DT  D 4 3   ? 75.31800  57.56300  50.00700  1.000 394.50000 ? 4   DT  D "C2'" 1 
ATOM   7750 C  "C1'" . DT  D 4 3   ? 74.92500  57.96800  51.45100  1.000 388.90000 ? 4   DT  D "C1'" 1 
ATOM   7751 N  N1    . DT  D 4 3   ? 73.38000  58.22900  51.70500  1.000 390.65000 ? 4   DT  D N1    1 
ATOM   7752 C  C2    . DT  D 4 3   ? 72.59800  57.26600  52.35400  1.000 383.02000 ? 4   DT  D C2    1 
ATOM   7753 O  O2    . DT  D 4 3   ? 73.03300  56.18100  52.73300  1.000 374.09000 ? 4   DT  D O2    1 
ATOM   7754 N  N3    . DT  D 4 3   ? 71.27200  57.62100  52.53600  1.000 382.11000 ? 4   DT  D N3    1 
ATOM   7755 C  C4    . DT  D 4 3   ? 70.65800  58.79200  52.15200  1.000 382.97000 ? 4   DT  D C4    1 
ATOM   7756 O  O4    . DT  D 4 3   ? 69.47500  59.00400  52.35800  1.000 379.69000 ? 4   DT  D O4    1 
ATOM   7757 C  C5    . DT  D 4 3   ? 71.51100  59.75900  51.48400  1.000 388.40000 ? 4   DT  D C5    1 
ATOM   7758 C  C7    . DT  D 4 3   ? 70.95600  61.08200  51.01700  1.000 385.88000 ? 4   DT  D C7    1 
ATOM   7759 C  C6    . DT  D 4 3   ? 72.80900  59.43300  51.30300  1.000 393.05000 ? 4   DT  D C6    1 
ATOM   7760 P  P     . DA  D 4 4   ? 78.31600  56.64200  49.12700  1.000 366.01000 ? 5   DA  D P     1 
ATOM   7761 O  OP1   . DA  D 4 4   ? 79.77400  56.73400  48.88100  1.000 368.85000 ? 5   DA  D OP1   1 
ATOM   7762 O  OP2   . DA  D 4 4   ? 77.41600  56.33600  47.98700  1.000 380.07000 ? 5   DA  D OP2   1 
ATOM   7763 O  "O5'" . DA  D 4 4   ? 78.09800  55.54600  50.23800  1.000 363.93000 ? 5   DA  D "O5'" 1 
ATOM   7764 C  "C5'" . DA  D 4 4   ? 79.19600  54.93600  50.85000  1.000 360.98000 ? 5   DA  D "C5'" 1 
ATOM   7765 C  "C4'" . DA  D 4 4   ? 78.98700  53.45300  50.83800  1.000 364.96000 ? 5   DA  D "C4'" 1 
ATOM   7766 O  "O4'" . DA  D 4 4   ? 77.60000  53.20200  51.22500  1.000 362.81000 ? 5   DA  D "O4'" 1 
ATOM   7767 C  "C3'" . DA  D 4 4   ? 79.17000  52.83000  49.46300  1.000 362.36000 ? 5   DA  D "C3'" 1 
ATOM   7768 O  "O3'" . DA  D 4 4   ? 79.80300  51.47500  49.53900  1.000 370.52000 ? 5   DA  D "O3'" 1 
ATOM   7769 C  "C2'" . DA  D 4 4   ? 77.75000  52.87400  48.88300  1.000 373.61000 ? 5   DA  D "C2'" 1 
ATOM   7770 C  "C1'" . DA  D 4 4   ? 76.88700  52.65500  50.13400  1.000 369.44000 ? 5   DA  D "C1'" 1 
ATOM   7771 N  N9    . DA  D 4 4   ? 75.52100  53.22900  50.09700  1.000 367.86000 ? 5   DA  D N9    1 
ATOM   7772 C  C8    . DA  D 4 4   ? 75.06500  54.26200  49.31000  1.000 375.51000 ? 5   DA  D C8    1 
ATOM   7773 N  N7    . DA  D 4 4   ? 73.78400  54.53500  49.49200  1.000 371.90000 ? 5   DA  D N7    1 
ATOM   7774 C  C5    . DA  D 4 4   ? 73.38000  53.62200  50.45900  1.000 355.57000 ? 5   DA  D C5    1 
ATOM   7775 C  C6    . DA  D 4 4   ? 72.13900  53.38200  51.10000  1.000 344.11000 ? 5   DA  D C6    1 
ATOM   7776 N  N6    . DA  D 4 4   ? 71.01500  54.05900  50.83500  1.000 343.74000 ? 5   DA  D N6    1 
ATOM   7777 N  N1    . DA  D 4 4   ? 72.09300  52.37900  51.99300  1.000 346.73000 ? 5   DA  D N1    1 
ATOM   7778 C  C2    . DA  D 4 4   ? 73.19800  51.67800  52.25400  1.000 347.11000 ? 5   DA  D C2    1 
ATOM   7779 N  N3    . DA  D 4 4   ? 74.41200  51.81900  51.74500  1.000 347.62000 ? 5   DA  D N3    1 
ATOM   7780 C  C4    . DA  D 4 4   ? 74.43800  52.81300  50.84000  1.000 352.88000 ? 5   DA  D C4    1 
ATOM   7781 P  P     . DC  D 4 5   ? 78.99700  50.08000  49.72200  1.000 371.38000 ? 6   DC  D P     1 
ATOM   7782 O  OP1   . DC  D 4 5   ? 78.30900  50.02100  51.03100  1.000 370.08000 ? 6   DC  D OP1   1 
ATOM   7783 O  OP2   . DC  D 4 5   ? 79.99100  49.04000  49.37300  1.000 368.22000 ? 6   DC  D OP2   1 
ATOM   7784 O  "O5'" . DC  D 4 5   ? 77.83300  50.10300  48.62100  1.000 377.11000 ? 6   DC  D "O5'" 1 
ATOM   7785 C  "C5'" . DC  D 4 5   ? 77.05200  48.94400  48.34600  1.000 371.42000 ? 6   DC  D "C5'" 1 
ATOM   7786 C  "C4'" . DC  D 4 5   ? 75.89000  48.72400  49.32300  1.000 364.88000 ? 6   DC  D "C4'" 1 
ATOM   7787 O  "O4'" . DC  D 4 5   ? 74.98000  49.89000  49.36900  1.000 372.42000 ? 6   DC  D "O4'" 1 
ATOM   7788 C  "C3'" . DC  D 4 5   ? 75.02300  47.54400  48.89600  1.000 367.44000 ? 6   DC  D "C3'" 1 
ATOM   7789 O  "O3'" . DC  D 4 5   ? 74.72700  46.66300  50.00400  1.000 355.71000 ? 6   DC  D "O3'" 1 
ATOM   7790 C  "C2'" . DC  D 4 5   ? 73.77800  48.21100  48.28000  1.000 373.68000 ? 6   DC  D "C2'" 1 
ATOM   7791 C  "C1'" . DC  D 4 5   ? 73.63800  49.45800  49.13500  1.000 371.86000 ? 6   DC  D "C1'" 1 
ATOM   7792 N  N1    . DC  D 4 5   ? 72.78200  50.62200  48.49900  1.000 368.52000 ? 6   DC  D N1    1 
ATOM   7793 C  C2    . DC  D 4 5   ? 71.61700  51.10300  49.16400  1.000 361.12000 ? 6   DC  D C2    1 
ATOM   7794 O  O2    . DC  D 4 5   ? 71.26500  50.58800  50.24300  1.000 347.94000 ? 6   DC  D O2    1 
ATOM   7795 N  N3    . DC  D 4 5   ? 70.90600  52.13200  48.59800  1.000 363.44000 ? 6   DC  D N3    1 
ATOM   7796 C  C4    . DC  D 4 5   ? 71.29800  52.66400  47.43100  1.000 361.40000 ? 6   DC  D C4    1 
ATOM   7797 N  N4    . DC  D 4 5   ? 70.55800  53.66700  46.92600  1.000 352.53000 ? 6   DC  D N4    1 
ATOM   7798 C  C5    . DC  D 4 5   ? 72.46200  52.19300  46.73300  1.000 361.43000 ? 6   DC  D C5    1 
ATOM   7799 C  C6    . DC  D 4 5   ? 73.16400  51.18700  47.28600  1.000 372.07000 ? 6   DC  D C6    1 
ATOM   7800 P  P     . DA  D 4 6   ? 75.14000  45.11100  49.89500  1.000 365.39000 ? 7   DA  D P     1 
ATOM   7801 O  OP1   . DA  D 4 6   ? 76.51500  44.96500  50.41900  1.000 364.05000 ? 7   DA  D OP1   1 
ATOM   7802 O  OP2   . DA  D 4 6   ? 74.80700  44.67200  48.51400  1.000 379.40000 ? 7   DA  D OP2   1 
ATOM   7803 O  "O5'" . DA  D 4 6   ? 74.07800  44.33700  50.79300  1.000 344.67000 ? 7   DA  D "O5'" 1 
ATOM   7804 C  "C5'" . DA  D 4 6   ? 72.88600  43.88200  50.18300  1.000 356.06000 ? 7   DA  D "C5'" 1 
ATOM   7805 C  "C4'" . DA  D 4 6   ? 71.73900  44.84800  50.44800  1.000 354.47000 ? 7   DA  D "C4'" 1 
ATOM   7806 O  "O4'" . DA  D 4 6   ? 71.76500  45.94100  49.49700  1.000 362.43000 ? 7   DA  D "O4'" 1 
ATOM   7807 C  "C3'" . DA  D 4 6   ? 70.36400  44.22900  50.26300  1.000 353.04000 ? 7   DA  D "C3'" 1 
ATOM   7808 O  "O3'" . DA  D 4 6   ? 69.82800  43.77000  51.53700  1.000 340.97000 ? 7   DA  D "O3'" 1 
ATOM   7809 C  "C2'" . DA  D 4 6   ? 69.50500  45.34600  49.61000  1.000 349.30000 ? 7   DA  D "C2'" 1 
ATOM   7810 C  "C1'" . DA  D 4 6   ? 70.47200  46.50600  49.47200  1.000 350.04000 ? 7   DA  D "C1'" 1 
ATOM   7811 N  N9    . DA  D 4 6   ? 70.29400  47.30900  48.25200  1.000 360.05000 ? 7   DA  D N9    1 
ATOM   7812 C  C8    . DA  D 4 6   ? 71.07300  47.28900  47.11900  1.000 368.99000 ? 7   DA  D C8    1 
ATOM   7813 N  N7    . DA  D 4 6   ? 70.69700  48.14000  46.18600  1.000 371.81000 ? 7   DA  D N7    1 
ATOM   7814 C  C5    . DA  D 4 6   ? 69.57000  48.75200  46.74100  1.000 368.84000 ? 7   DA  D C5    1 
ATOM   7815 C  C6    . DA  D 4 6   ? 68.68600  49.75800  46.25900  1.000 370.20000 ? 7   DA  D C6    1 
ATOM   7816 N  N6    . DA  D 4 6   ? 68.80100  50.33400  45.04600  1.000 375.76000 ? 7   DA  D N6    1 
ATOM   7817 N  N1    . DA  D 4 6   ? 67.66400  50.13200  47.06900  1.000 363.37000 ? 7   DA  D N1    1 
ATOM   7818 C  C2    . DA  D 4 6   ? 67.52000  49.51800  48.25100  1.000 352.08000 ? 7   DA  D C2    1 
ATOM   7819 N  N3    . DA  D 4 6   ? 68.29500  48.60500  48.83000  1.000 347.42000 ? 7   DA  D N3    1 
ATOM   7820 C  C4    . DA  D 4 6   ? 69.30600  48.24600  48.01100  1.000 359.00000 ? 7   DA  D C4    1 
ATOM   7821 P  P     . DA  D 4 7   ? 69.25800  42.26500  51.67500  1.000 346.91000 ? 8   DA  D P     1 
ATOM   7822 O  OP1   . DA  D 4 7   ? 69.29300  41.76900  53.06000  1.000 360.39000 ? 8   DA  D OP1   1 
ATOM   7823 O  OP2   . DA  D 4 7   ? 70.06800  41.47100  50.72800  1.000 360.74000 ? 8   DA  D OP2   1 
ATOM   7824 O  "O5'" . DA  D 4 7   ? 67.73200  42.38400  51.15500  1.000 350.54000 ? 8   DA  D "O5'" 1 
ATOM   7825 C  "C5'" . DA  D 4 7   ? 67.47000  42.71100  49.75900  1.000 374.16000 ? 8   DA  D "C5'" 1 
ATOM   7826 C  "C4'" . DA  D 4 7   ? 66.17000  43.49600  49.58700  1.000 376.92000 ? 8   DA  D "C4'" 1 
ATOM   7827 O  "O4'" . DA  D 4 7   ? 66.36300  44.65600  48.68500  1.000 375.85000 ? 8   DA  D "O4'" 1 
ATOM   7828 C  "C3'" . DA  D 4 7   ? 65.04600  42.67400  49.00400  1.000 391.81000 ? 8   DA  D "C3'" 1 
ATOM   7829 O  "O3'" . DA  D 4 7   ? 63.75700  42.96300  49.75900  1.000 375.39000 ? 8   DA  D "O3'" 1 
ATOM   7830 C  "C2'" . DA  D 4 7   ? 65.11700  43.01200  47.46500  1.000 396.99000 ? 8   DA  D "C2'" 1 
ATOM   7831 C  "C1'" . DA  D 4 7   ? 65.71000  44.44400  47.43200  1.000 385.39000 ? 8   DA  D "C1'" 1 
ATOM   7832 N  N9    . DA  D 4 7   ? 66.66800  44.82800  46.32300  1.000 380.49000 ? 8   DA  D N9    1 
ATOM   7833 C  C8    . DA  D 4 7   ? 67.72100  44.09300  45.79600  1.000 380.03000 ? 8   DA  D C8    1 
ATOM   7834 N  N7    . DA  D 4 7   ? 68.41600  44.74200  44.86600  1.000 381.74000 ? 8   DA  D N7    1 
ATOM   7835 C  C5    . DA  D 4 7   ? 67.80100  45.98900  44.78700  1.000 378.64000 ? 8   DA  D C5    1 
ATOM   7836 C  C6    . DA  D 4 7   ? 68.05100  47.14700  43.98500  1.000 376.99000 ? 8   DA  D C6    1 
ATOM   7837 N  N6    . DA  D 4 7   ? 69.04300  47.23300  43.06900  1.000 372.33000 ? 8   DA  D N6    1 
ATOM   7838 N  N1    . DA  D 4 7   ? 67.23200  48.21100  44.16600  1.000 376.62000 ? 8   DA  D N1    1 
ATOM   7839 C  C2    . DA  D 4 7   ? 66.24300  48.13800  45.07400  1.000 371.79000 ? 8   DA  D C2    1 
ATOM   7840 N  N3    . DA  D 4 7   ? 65.91300  47.12500  45.88200  1.000 368.43000 ? 8   DA  D N3    1 
ATOM   7841 C  C4    . DA  D 4 7   ? 66.73300  46.06500  45.68600  1.000 374.00000 ? 8   DA  D C4    1 
ATOM   7842 P  P     . DC  D 4 8   ? 62.57100  43.85500  49.12800  1.000 378.28000 ? 9   DC  D P     1 
ATOM   7843 O  OP1   . DC  D 4 8   ? 63.17100  45.19500  48.84800  1.000 372.09000 ? 9   DC  D OP1   1 
ATOM   7844 O  OP2   . DC  D 4 8   ? 61.40200  43.72000  50.06300  1.000 378.00000 ? 9   DC  D OP2   1 
ATOM   7845 O  "O5'" . DC  D 4 8   ? 62.31000  43.05600  47.72300  1.000 406.38000 ? 9   DC  D "O5'" 1 
ATOM   7846 C  "C5'" . DC  D 4 8   ? 61.12900  43.19100  46.96100  1.000 398.48000 ? 9   DC  D "C5'" 1 
ATOM   7847 C  "C4'" . DC  D 4 8   ? 60.78300  44.65100  46.79300  1.000 392.23000 ? 9   DC  D "C4'" 1 
ATOM   7848 O  "O4'" . DC  D 4 8   ? 61.93900  45.40300  46.29700  1.000 386.98000 ? 9   DC  D "O4'" 1 
ATOM   7849 C  "C3'" . DC  D 4 8   ? 59.66400  44.91700  45.82100  1.000 394.60000 ? 9   DC  D "C3'" 1 
ATOM   7850 O  "O3'" . DC  D 4 8   ? 58.95700  46.05800  46.30900  1.000 396.35000 ? 9   DC  D "O3'" 1 
ATOM   7851 C  "C2'" . DC  D 4 8   ? 60.42900  45.17700  44.50300  1.000 386.44000 ? 9   DC  D "C2'" 1 
ATOM   7852 C  "C1'" . DC  D 4 8   ? 61.67800  45.90400  44.99400  1.000 379.80000 ? 9   DC  D "C1'" 1 
ATOM   7853 N  N1    . DC  D 4 8   ? 62.92400  45.72700  44.08600  1.000 377.05000 ? 9   DC  D N1    1 
ATOM   7854 C  C2    . DC  D 4 8   ? 63.40000  46.80500  43.30300  1.000 369.90000 ? 9   DC  D C2    1 
ATOM   7855 O  O2    . DC  D 4 8   ? 62.81700  47.89700  43.36900  1.000 361.34000 ? 9   DC  D O2    1 
ATOM   7856 N  N3    . DC  D 4 8   ? 64.50000  46.61500  42.50000  1.000 374.07000 ? 9   DC  D N3    1 
ATOM   7857 C  C4    . DC  D 4 8   ? 65.10100  45.41300  42.46200  1.000 376.36000 ? 9   DC  D C4    1 
ATOM   7858 N  N4    . DC  D 4 8   ? 66.17400  45.26500  41.66400  1.000 371.82000 ? 9   DC  D N4    1 
ATOM   7859 C  C5    . DC  D 4 8   ? 64.62600  44.30700  43.24100  1.000 383.21000 ? 9   DC  D C5    1 
ATOM   7860 C  C6    . DC  D 4 8   ? 63.55100  44.50500  44.01500  1.000 383.17000 ? 9   DC  D C6    1 
ATOM   7861 P  P     . DC  D 4 9   ? 57.50500  46.45300  45.73300  1.000 406.82000 ? 10  DC  D P     1 
ATOM   7862 O  OP1   . DC  D 4 9   ? 57.02900  47.60200  46.53700  1.000 390.20000 ? 10  DC  D OP1   1 
ATOM   7863 O  OP2   . DC  D 4 9   ? 56.64000  45.26800  45.78400  1.000 395.10000 ? 10  DC  D OP2   1 
ATOM   7864 O  "O5'" . DC  D 4 9   ? 57.80700  46.86900  44.20200  1.000 392.43000 ? 10  DC  D "O5'" 1 
ATOM   7865 C  "C5'" . DC  D 4 9   ? 58.69400  47.97400  43.91200  1.000 379.10000 ? 10  DC  D "C5'" 1 
ATOM   7866 C  "C4'" . DC  D 4 9   ? 58.29100  48.65900  42.61900  1.000 371.42000 ? 10  DC  D "C4'" 1 
ATOM   7867 O  "O4'" . DC  D 4 9   ? 59.24100  48.33500  41.57700  1.000 366.28000 ? 10  DC  D "O4'" 1 
ATOM   7868 C  "C3'" . DC  D 4 9   ? 56.91500  48.26500  42.09200  1.000 373.69000 ? 10  DC  D "C3'" 1 
ATOM   7869 O  "O3'" . DC  D 4 9   ? 56.27000  49.40900  41.48700  1.000 369.82000 ? 10  DC  D "O3'" 1 
ATOM   7870 C  "C2'" . DC  D 4 9   ? 57.24100  47.10900  41.13000  1.000 375.94000 ? 10  DC  D "C2'" 1 
ATOM   7871 C  "C1'" . DC  D 4 9   ? 58.69900  47.35800  40.70900  1.000 372.25000 ? 10  DC  D "C1'" 1 
ATOM   7872 N  N1    . DC  D 4 9   ? 59.59000  46.14400  40.73100  1.000 372.48000 ? 10  DC  D N1    1 
ATOM   7873 C  C2    . DC  D 4 9   ? 60.91500  46.27300  40.28700  1.000 370.93000 ? 10  DC  D C2    1 
ATOM   7874 O  O2    . DC  D 4 9   ? 61.32100  47.38400  39.87100  1.000 367.65000 ? 10  DC  D O2    1 
ATOM   7875 N  N3    . DC  D 4 9   ? 61.71900  45.17900  40.32400  1.000 373.31000 ? 10  DC  D N3    1 
ATOM   7876 C  C4    . DC  D 4 9   ? 61.24600  44.00600  40.77700  1.000 368.23000 ? 10  DC  D C4    1 
ATOM   7877 N  N4    . DC  D 4 9   ? 62.08400  42.96600  40.80900  1.000 364.03000 ? 10  DC  D N4    1 
ATOM   7878 C  C5    . DC  D 4 9   ? 59.89800  43.85600  41.22600  1.000 363.38000 ? 10  DC  D C5    1 
ATOM   7879 C  C6    . DC  D 4 9   ? 59.11100  44.93700  41.18800  1.000 370.09000 ? 10  DC  D C6    1 
ATOM   7880 P  P     . DT  D 4 10  ? 55.47500  49.26500  40.09300  1.000 370.34000 ? 11  DT  D P     1 
ATOM   7881 O  OP1   . DT  D 4 10  ? 54.85300  50.57700  39.84000  1.000 376.30000 ? 11  DT  D OP1   1 
ATOM   7882 O  OP2   . DT  D 4 10  ? 54.59900  48.07500  40.12900  1.000 368.17000 ? 11  DT  D OP2   1 
ATOM   7883 O  "O5'" . DT  D 4 10  ? 56.63700  49.03100  39.02400  1.000 369.22000 ? 11  DT  D "O5'" 1 
ATOM   7884 C  "C5'" . DT  D 4 10  ? 57.74200  49.94800  38.92300  1.000 366.86000 ? 11  DT  D "C5'" 1 
ATOM   7885 C  "C4'" . DT  D 4 10  ? 57.90800  50.33000  37.48600  1.000 359.66000 ? 11  DT  D "C4'" 1 
ATOM   7886 O  "O4'" . DT  D 4 10  ? 58.80200  49.38200  36.85000  1.000 360.57000 ? 11  DT  D "O4'" 1 
ATOM   7887 C  "C3'" . DT  D 4 10  ? 56.59300  50.28000  36.72800  1.000 358.31000 ? 11  DT  D "C3'" 1 
ATOM   7888 O  "O3'" . DT  D 4 10  ? 56.46900  51.39900  35.85300  1.000 361.76000 ? 11  DT  D "O3'" 1 
ATOM   7889 C  "C2'" . DT  D 4 10  ? 56.60900  48.91200  36.02900  1.000 365.81000 ? 11  DT  D "C2'" 1 
ATOM   7890 C  "C1'" . DT  D 4 10  ? 58.06300  48.45500  36.07600  1.000 367.21000 ? 11  DT  D "C1'" 1 
ATOM   7891 N  N1    . DT  D 4 10  ? 58.27000  47.04900  36.63700  1.000 370.23000 ? 11  DT  D N1    1 
ATOM   7892 C  C2    . DT  D 4 10  ? 59.54100  46.51800  36.67200  1.000 372.40000 ? 11  DT  D C2    1 
ATOM   7893 O  O2    . DT  D 4 10  ? 60.53700  47.13200  36.30300  1.000 371.20000 ? 11  DT  D O2    1 
ATOM   7894 N  N3    . DT  D 4 10  ? 59.61900  45.23500  37.17700  1.000 370.94000 ? 11  DT  D N3    1 
ATOM   7895 C  C4    . DT  D 4 10  ? 58.58400  44.44000  37.62500  1.000 359.42000 ? 11  DT  D C4    1 
ATOM   7896 O  O4    . DT  D 4 10  ? 58.75700  43.29300  38.06300  1.000 346.61000 ? 11  DT  D O4    1 
ATOM   7897 C  C5    . DT  D 4 10  ? 57.27200  45.04600  37.54800  1.000 356.71000 ? 11  DT  D C5    1 
ATOM   7898 C  C7    . DT  D 4 10  ? 56.06200  44.28500  38.00500  1.000 349.98000 ? 11  DT  D C7    1 
ATOM   7899 C  C6    . DT  D 4 10  ? 57.17700  46.30600  37.05700  1.000 364.84000 ? 11  DT  D C6    1 
ATOM   7900 P  P     . DA  D 4 11  ? 56.98800  51.35300  34.33800  1.000 391.24000 ? 12  DA  D P     1 
ATOM   7901 O  OP1   . DA  D 4 11  ? 58.38800  50.84900  34.32900  1.000 380.82000 ? 12  DA  D OP1   1 
ATOM   7902 O  OP2   . DA  D 4 11  ? 56.70100  52.71300  33.82400  1.000 386.16000 ? 12  DA  D OP2   1 
ATOM   7903 O  "O5'" . DA  D 4 11  ? 55.99200  50.33700  33.59700  1.000 388.76000 ? 12  DA  D "O5'" 1 
ATOM   7904 C  "C5'" . DA  D 4 11  ? 55.85500  50.38300  32.18700  1.000 383.68000 ? 12  DA  D "C5'" 1 
ATOM   7905 C  "C4'" . DA  D 4 11  ? 57.21600  50.35300  31.52000  1.000 373.85000 ? 12  DA  D "C4'" 1 
ATOM   7906 O  "O4'" . DA  D 4 11  ? 58.00100  49.26500  32.08300  1.000 368.03000 ? 12  DA  D "O4'" 1 
ATOM   7907 C  "C3'" . DA  D 4 11  ? 57.17900  50.04600  30.05400  1.000 365.32000 ? 12  DA  D "C3'" 1 
ATOM   7908 O  "O3'" . DA  D 4 11  ? 58.43500  50.37400  29.48100  1.000 360.30000 ? 12  DA  D "O3'" 1 
ATOM   7909 C  "C2'" . DA  D 4 11  ? 56.93100  48.53600  30.11300  1.000 360.96000 ? 12  DA  D "C2'" 1 
ATOM   7910 C  "C1'" . DA  D 4 11  ? 57.86300  48.12100  31.26000  1.000 360.37000 ? 12  DA  D "C1'" 1 
ATOM   7911 N  N9    . DA  D 4 11  ? 57.37600  46.99800  32.08700  1.000 357.47000 ? 12  DA  D N9    1 
ATOM   7912 C  C8    . DA  D 4 11  ? 56.08200  46.73900  32.48500  1.000 355.51000 ? 12  DA  D C8    1 
ATOM   7913 N  N7    . DA  D 4 11  ? 55.96100  45.65900  33.23400  1.000 345.80000 ? 12  DA  D N7    1 
ATOM   7914 C  C5    . DA  D 4 11  ? 57.26300  45.18700  33.33700  1.000 348.80000 ? 12  DA  D C5    1 
ATOM   7915 C  C6    . DA  D 4 11  ? 57.82600  44.06900  33.99400  1.000 350.56000 ? 12  DA  D C6    1 
ATOM   7916 N  N6    . DA  D 4 11  ? 57.11400  43.18000  34.70300  1.000 343.11000 ? 12  DA  D N6    1 
ATOM   7917 N  N1    . DA  D 4 11  ? 59.16200  43.89200  33.88100  1.000 360.32000 ? 12  DA  D N1    1 
ATOM   7918 C  C2    . DA  D 4 11  ? 59.88200  44.76900  33.16800  1.000 360.45000 ? 12  DA  D C2    1 
ATOM   7919 N  N3    . DA  D 4 11  ? 59.47100  45.85000  32.51300  1.000 353.59000 ? 12  DA  D N3    1 
ATOM   7920 C  C4    . DA  D 4 11  ? 58.14200  46.00200  32.63300  1.000 352.41000 ? 12  DA  D C4    1 
ATOM   7921 P  P     . DC  D 4 12  ? 58.60600  50.50100  27.89400  1.000 364.24000 ? 13  DC  D P     1 
ATOM   7922 O  OP1   . DC  D 4 12  ? 59.22100  51.81300  27.64800  1.000 366.91000 ? 13  DC  D OP1   1 
ATOM   7923 O  OP2   . DC  D 4 12  ? 57.31500  50.20200  27.23500  1.000 358.99000 ? 13  DC  D OP2   1 
ATOM   7924 O  "O5'" . DC  D 4 12  ? 59.68600  49.35600  27.54300  1.000 363.94000 ? 13  DC  D "O5'" 1 
ATOM   7925 C  "C5'" . DC  D 4 12  ? 59.43400  47.97500  27.93100  1.000 351.00000 ? 13  DC  D "C5'" 1 
ATOM   7926 C  "C4'" . DC  D 4 12  ? 59.50700  46.95900  26.78300  1.000 343.58000 ? 13  DC  D "C4'" 1 
ATOM   7927 O  "O4'" . DC  D 4 12  ? 59.42600  45.60200  27.31100  1.000 339.89000 ? 13  DC  D "O4'" 1 
ATOM   7928 C  "C3'" . DC  D 4 12  ? 58.40100  47.03900  25.75200  1.000 342.97000 ? 13  DC  D "C3'" 1 
ATOM   7929 O  "O3'" . DC  D 4 12  ? 58.92700  46.61600  24.49100  1.000 352.10000 ? 13  DC  D "O3'" 1 
ATOM   7930 C  "C2'" . DC  D 4 12  ? 57.33100  46.09400  26.28400  1.000 345.59000 ? 13  DC  D "C2'" 1 
ATOM   7931 C  "C1'" . DC  D 4 12  ? 58.15000  45.03800  27.02300  1.000 341.79000 ? 13  DC  D "C1'" 1 
ATOM   7932 N  N1    . DC  D 4 12  ? 57.47800  44.56500  28.29800  1.000 345.47000 ? 13  DC  D N1    1 
ATOM   7933 C  C2    . DC  D 4 12  ? 58.10300  43.62300  29.11400  1.000 342.75000 ? 13  DC  D C2    1 
ATOM   7934 O  O2    . DC  D 4 12  ? 59.21300  43.19000  28.78100  1.000 341.93000 ? 13  DC  D O2    1 
ATOM   7935 N  N3    . DC  D 4 12  ? 57.47200  43.21900  30.25900  1.000 337.47000 ? 13  DC  D N3    1 
ATOM   7936 C  C4    . DC  D 4 12  ? 56.27300  43.71400  30.57600  1.000 334.53000 ? 13  DC  D C4    1 
ATOM   7937 N  N4    . DC  D 4 12  ? 55.70600  43.27700  31.70700  1.000 334.20000 ? 13  DC  D N4    1 
ATOM   7938 C  C5    . DC  D 4 12  ? 55.60700  44.67600  29.75300  1.000 340.49000 ? 13  DC  D C5    1 
ATOM   7939 C  C6    . DC  D 4 12  ? 56.23200  45.06200  28.63500  1.000 346.19000 ? 13  DC  D C6    1 
ATOM   7940 P  P     . DT  D 4 13  ? 58.07400  45.69500  23.48700  1.000 344.66000 ? 14  DT  D P     1 
ATOM   7941 O  OP1   . DT  D 4 13  ? 58.76600  45.89100  22.21000  1.000 355.36000 ? 14  DT  D OP1   1 
ATOM   7942 O  OP2   . DT  D 4 13  ? 56.61700  45.95900  23.49300  1.000 336.57000 ? 14  DT  D OP2   1 
ATOM   7943 O  "O5'" . DT  D 4 13  ? 58.33900  44.20100  23.98800  1.000 335.32000 ? 14  DT  D "O5'" 1 
ATOM   7944 C  "C5'" . DT  D 4 13  ? 59.68100  43.71000  24.06600  1.000 330.34000 ? 14  DT  D "C5'" 1 
ATOM   7945 C  "C4'" . DT  D 4 13  ? 59.68300  42.20400  24.10700  1.000 323.84000 ? 14  DT  D "C4'" 1 
ATOM   7946 O  "O4'" . DT  D 4 13  ? 59.01900  41.77200  25.31000  1.000 319.02000 ? 14  DT  D "O4'" 1 
ATOM   7947 C  "C3'" . DT  D 4 13  ? 58.93400  41.54600  22.95900  1.000 325.65000 ? 14  DT  D "C3'" 1 
ATOM   7948 O  "O3'" . DT  D 4 13  ? 59.57700  40.34900  22.59300  1.000 327.86000 ? 14  DT  D "O3'" 1 
ATOM   7949 C  "C2'" . DT  D 4 13  ? 57.55800  41.28900  23.55300  1.000 320.62000 ? 14  DT  D "C2'" 1 
ATOM   7950 C  "C1'" . DT  D 4 13  ? 57.91100  40.96900  24.98400  1.000 321.34000 ? 14  DT  D "C1'" 1 
ATOM   7951 N  N1    . DT  D 4 13  ? 56.86700  41.32000  25.90100  1.000 318.75000 ? 14  DT  D N1    1 
ATOM   7952 C  C2    . DT  D 4 13  ? 56.95800  40.88100  27.18900  1.000 318.59000 ? 14  DT  D C2    1 
ATOM   7953 O  O2    . DT  D 4 13  ? 57.87100  40.18800  27.59000  1.000 311.79000 ? 14  DT  D O2    1 
ATOM   7954 N  N3    . DT  D 4 13  ? 55.93700  41.27300  27.99700  1.000 326.94000 ? 14  DT  D N3    1 
ATOM   7955 C  C4    . DT  D 4 13  ? 54.85100  42.05900  27.65000  1.000 332.17000 ? 14  DT  D C4    1 
ATOM   7956 O  O4    . DT  D 4 13  ? 53.97700  42.36000  28.45900  1.000 335.01000 ? 14  DT  D O4    1 
ATOM   7957 C  C5    . DT  D 4 13  ? 54.82100  42.49900  26.26500  1.000 333.28000 ? 14  DT  D C5    1 
ATOM   7958 C  C7    . DT  D 4 13  ? 53.69500  43.35900  25.75300  1.000 336.10000 ? 14  DT  D C7    1 
ATOM   7959 C  C6    . DT  D 4 13  ? 55.82500  42.11600  25.47100  1.000 326.60000 ? 14  DT  D C6    1 
ATOM   7960 P  P     . DA  D 4 14  ? 59.03500  39.50100  21.34600  1.000 310.13000 ? 15  DA  D P     1 
ATOM   7961 O  OP1   . DA  D 4 14  ? 60.14000  39.32000  20.37800  1.000 312.86000 ? 15  DA  D OP1   1 
ATOM   7962 O  OP2   . DA  D 4 14  ? 57.74500  40.07000  20.89900  1.000 309.90000 ? 15  DA  D OP2   1 
ATOM   7963 O  "O5'" . DA  D 4 14  ? 58.71100  38.09500  21.98400  1.000 305.14000 ? 15  DA  D "O5'" 1 
ATOM   7964 C  "C5'" . DA  D 4 14  ? 59.75400  37.24600  22.33900  1.000 301.52000 ? 15  DA  D "C5'" 1 
ATOM   7965 C  "C4'" . DA  D 4 14  ? 59.21300  36.12000  23.16500  1.000 299.68000 ? 15  DA  D "C4'" 1 
ATOM   7966 O  "O4'" . DA  D 4 14  ? 58.29300  36.66300  24.13900  1.000 295.82000 ? 15  DA  D "O4'" 1 
ATOM   7967 C  "C3'" . DA  D 4 14  ? 58.40600  35.11400  22.37900  1.000 306.17000 ? 15  DA  D "C3'" 1 
ATOM   7968 O  "O3'" . DA  D 4 14  ? 58.45200  33.91400  23.04500  1.000 299.89000 ? 15  DA  D "O3'" 1 
ATOM   7969 C  "C2'" . DA  D 4 14  ? 57.01600  35.70200  22.45900  1.000 308.39000 ? 15  DA  D "C2'" 1 
ATOM   7970 C  "C1'" . DA  D 4 14  ? 57.01700  36.13300  23.90100  1.000 304.15000 ? 15  DA  D "C1'" 1 
ATOM   7971 N  N9    . DA  D 4 14  ? 56.06000  37.15900  24.21300  1.000 301.13000 ? 15  DA  D N9    1 
ATOM   7972 C  C8    . DA  D 4 14  ? 55.61300  38.14900  23.38300  1.000 307.81000 ? 15  DA  D C8    1 
ATOM   7973 N  N7    . DA  D 4 14  ? 54.73700  38.94100  23.95700  1.000 310.66000 ? 15  DA  D N7    1 
ATOM   7974 C  C5    . DA  D 4 14  ? 54.63300  38.43200  25.23700  1.000 304.92000 ? 15  DA  D C5    1 
ATOM   7975 C  C6    . DA  D 4 14  ? 53.87300  38.81300  26.35100  1.000 309.98000 ? 15  DA  D C6    1 
ATOM   7976 N  N6    . DA  D 4 14  ? 53.02800  39.84500  26.33800  1.000 316.03000 ? 15  DA  D N6    1 
ATOM   7977 N  N1    . DA  D 4 14  ? 54.01000  38.08700  27.47800  1.000 314.30000 ? 15  DA  D N1    1 
ATOM   7978 C  C2    . DA  D 4 14  ? 54.84800  37.05500  27.48400  1.000 313.86000 ? 15  DA  D C2    1 
ATOM   7979 N  N3    . DA  D 4 14  ? 55.61000  36.60200  26.49900  1.000 312.34000 ? 15  DA  D N3    1 
ATOM   7980 C  C4    . DA  D 4 14  ? 55.45000  37.34300  25.40000  1.000 303.95000 ? 15  DA  D C4    1 
ATOM   7981 P  P     . DC  D 4 15  ? 58.71800  32.58500  22.20300  1.000 298.55000 ? 16  DC  D P     1 
ATOM   7982 O  OP1   . DC  D 4 15  ? 59.81100  31.86800  22.88100  1.000 311.33000 ? 16  DC  D OP1   1 
ATOM   7983 O  OP2   . DC  D 4 15  ? 58.91700  33.02200  20.80600  1.000 311.83000 ? 16  DC  D OP2   1 
ATOM   7984 O  "O5'" . DC  D 4 15  ? 57.35400  31.75300  22.40200  1.000 303.40000 ? 16  DC  D "O5'" 1 
ATOM   7985 C  "C5'" . DC  D 4 15  ? 56.06900  32.42400  22.48300  1.000 297.18000 ? 16  DC  D "C5'" 1 
ATOM   7986 C  "C4'" . DC  D 4 15  ? 55.40800  32.20600  23.83500  1.000 297.32000 ? 16  DC  D "C4'" 1 
ATOM   7987 O  "O4'" . DC  D 4 15  ? 54.86500  33.44900  24.32600  1.000 287.48000 ? 16  DC  D "O4'" 1 
ATOM   7988 C  "C3'" . DC  D 4 15  ? 54.25500  31.21700  23.84800  1.000 310.47000 ? 16  DC  D "C3'" 1 
ATOM   7989 O  "O3'" . DC  D 4 15  ? 54.31600  30.53300  25.03200  1.000 308.26000 ? 16  DC  D "O3'" 1 
ATOM   7990 C  "C2'" . DC  D 4 15  ? 53.02700  32.11800  23.79300  1.000 301.08000 ? 16  DC  D "C2'" 1 
ATOM   7991 C  "C1'" . DC  D 4 15  ? 53.49700  33.29300  24.62200  1.000 296.61000 ? 16  DC  D "C1'" 1 
ATOM   7992 N  N1    . DC  D 4 15  ? 52.86000  34.55600  24.28800  1.000 298.27000 ? 16  DC  D N1    1 
ATOM   7993 C  C2    . DC  D 4 15  ? 52.51500  35.42400  25.30500  1.000 300.91000 ? 16  DC  D C2    1 
ATOM   7994 O  O2    . DC  D 4 15  ? 52.70900  35.07900  26.46400  1.000 302.54000 ? 16  DC  D O2    1 
ATOM   7995 N  N3    . DC  D 4 15  ? 51.95200  36.61500  24.99900  1.000 299.09000 ? 16  DC  D N3    1 
ATOM   7996 C  C4    . DC  D 4 15  ? 51.75600  36.94500  23.73200  1.000 297.20000 ? 16  DC  D C4    1 
ATOM   7997 N  N4    . DC  D 4 15  ? 51.19600  38.13200  23.47300  1.000 304.47000 ? 16  DC  D N4    1 
ATOM   7998 C  C5    . DC  D 4 15  ? 52.12700  36.07100  22.67300  1.000 300.03000 ? 16  DC  D C5    1 
ATOM   7999 C  C6    . DC  D 4 15  ? 52.68200  34.90000  22.99500  1.000 301.67000 ? 16  DC  D C6    1 
ATOM   8000 P  P     . DC  D 4 16  ? 53.74000  29.05400  25.12400  1.000 306.32000 ? 17  DC  D P     1 
ATOM   8001 O  OP1   . DC  D 4 16  ? 54.44100  28.36400  26.23300  1.000 291.97000 ? 17  DC  D OP1   1 
ATOM   8002 O  OP2   . DC  D 4 16  ? 53.74300  28.50600  23.76300  1.000 291.95000 ? 17  DC  D OP2   1 
ATOM   8003 O  "O5'" . DC  D 4 16  ? 52.25000  29.28800  25.58400  1.000 296.89000 ? 17  DC  D "O5'" 1 
ATOM   8004 C  "C5'" . DC  D 4 16  ? 51.98200  29.56100  26.93800  1.000 299.34000 ? 17  DC  D "C5'" 1 
ATOM   8005 C  "C4'" . DC  D 4 16  ? 50.50700  29.86800  27.12300  1.000 300.82000 ? 17  DC  D "C4'" 1 
ATOM   8006 O  "O4'" . DC  D 4 16  ? 50.29700  31.21900  26.74600  1.000 299.48000 ? 17  DC  D "O4'" 1 
ATOM   8007 C  "C3'" . DC  D 4 16  ? 49.55600  29.04200  26.26000  1.000 301.69000 ? 17  DC  D "C3'" 1 
ATOM   8008 O  "O3'" . DC  D 4 16  ? 48.98300  27.95000  27.00000  1.000 305.86000 ? 17  DC  D "O3'" 1 
ATOM   8009 C  "C2'" . DC  D 4 16  ? 48.50900  30.03800  25.78400  1.000 297.09000 ? 17  DC  D "C2'" 1 
ATOM   8010 C  "C1'" . DC  D 4 16  ? 48.99000  31.37700  26.31800  1.000 296.29000 ? 17  DC  D "C1'" 1 
ATOM   8011 N  N1    . DC  D 4 16  ? 49.02800  32.31900  25.28800  1.000 295.59000 ? 17  DC  D N1    1 
ATOM   8012 C  C2    . DC  D 4 16  ? 48.79700  33.64000  25.56400  1.000 301.48000 ? 17  DC  D C2    1 
ATOM   8013 O  O2    . DC  D 4 16  ? 48.57400  33.97200  26.72600  1.000 308.47000 ? 17  DC  D O2    1 
ATOM   8014 N  N3    . DC  D 4 16  ? 48.83500  34.53000  24.54900  1.000 304.17000 ? 17  DC  D N3    1 
ATOM   8015 C  C4    . DC  D 4 16  ? 49.08400  34.11100  23.30900  1.000 305.11000 ? 17  DC  D C4    1 
ATOM   8016 N  N4    . DC  D 4 16  ? 49.11700  35.02400  22.33400  1.000 311.36000 ? 17  DC  D N4    1 
ATOM   8017 C  C5    . DC  D 4 16  ? 49.31800  32.74000  23.02100  1.000 303.88000 ? 17  DC  D C5    1 
ATOM   8018 C  C6    . DC  D 4 16  ? 49.27900  31.89100  24.03500  1.000 303.26000 ? 17  DC  D C6    1 
ATOM   8019 P  P     . DT  D 4 17  ? 48.53100  28.09900  28.52900  1.000 309.94000 ? 18  DT  D P     1 
ATOM   8020 O  OP1   . DT  D 4 17  ? 49.69600  28.26400  29.42000  1.000 297.72000 ? 18  DT  D OP1   1 
ATOM   8021 O  OP2   . DT  D 4 17  ? 47.57000  27.02600  28.80600  1.000 300.03000 ? 18  DT  D OP2   1 
ATOM   8022 O  "O5'" . DT  D 4 17  ? 47.62500  29.36400  28.48900  1.000 297.22000 ? 18  DT  D "O5'" 1 
ATOM   8023 C  "C5'" . DT  D 4 17  ? 46.37400  29.23600  28.07400  1.000 291.57000 ? 18  DT  D "C5'" 1 
ATOM   8024 C  "C4'" . DT  D 4 17  ? 45.55200  30.26300  28.75700  1.000 295.04000 ? 18  DT  D "C4'" 1 
ATOM   8025 O  "O4'" . DT  D 4 17  ? 45.64200  31.50700  28.00900  1.000 299.22000 ? 18  DT  D "O4'" 1 
ATOM   8026 C  "C3'" . DT  D 4 17  ? 44.05300  29.96400  28.83900  1.000 297.47000 ? 18  DT  D "C3'" 1 
ATOM   8027 O  "O3'" . DT  D 4 17  ? 43.54000  30.75800  29.89800  1.000 313.85000 ? 18  DT  D "O3'" 1 
ATOM   8028 C  "C2'" . DT  D 4 17  ? 43.56900  30.46700  27.49900  1.000 293.30000 ? 18  DT  D "C2'" 1 
ATOM   8029 C  "C1'" . DT  D 4 17  ? 44.34700  31.75300  27.38800  1.000 295.77000 ? 18  DT  D "C1'" 1 
ATOM   8030 N  N1    . DT  D 4 17  ? 44.54700  32.14100  25.98800  1.000 289.73000 ? 18  DT  D N1    1 
ATOM   8031 C  C2    . DT  D 4 17  ? 44.17700  33.38400  25.55900  1.000 292.47000 ? 18  DT  D C2    1 
ATOM   8032 O  O2    . DT  D 4 17  ? 43.64400  34.24400  26.33200  1.000 295.32000 ? 18  DT  D O2    1 
ATOM   8033 N  N3    . DT  D 4 17  ? 44.50000  33.63500  24.28100  1.000 297.83000 ? 18  DT  D N3    1 
ATOM   8034 C  C4    . DT  D 4 17  ? 45.06300  32.73200  23.42400  1.000 304.54000 ? 18  DT  D C4    1 
ATOM   8035 O  O4    . DT  D 4 17  ? 45.27900  33.00500  22.22300  1.000 315.52000 ? 18  DT  D O4    1 
ATOM   8036 C  C5    . DT  D 4 17  ? 45.39600  31.44500  23.96500  1.000 299.40000 ? 18  DT  D C5    1 
ATOM   8037 C  C7    . DT  D 4 17  ? 46.04900  30.37100  23.11600  1.000 311.94000 ? 18  DT  D C7    1 
ATOM   8038 C  C6    . DT  D 4 17  ? 45.10300  31.23700  25.20200  1.000 293.18000 ? 18  DT  D C6    1 
ATOM   8039 P  P     . DC  D 4 18  ? 42.65800  30.11200  31.06500  1.000 338.40000 ? 19  DC  D P     1 
ATOM   8040 O  OP1   . DC  D 4 18  ? 43.52200  29.95100  32.26600  1.000 331.93000 ? 19  DC  D OP1   1 
ATOM   8041 O  OP2   . DC  D 4 18  ? 42.10800  28.92400  30.37800  1.000 311.71000 ? 19  DC  D OP2   1 
ATOM   8042 O  "O5'" . DC  D 4 18  ? 41.54600  31.23200  31.39300  1.000 333.85000 ? 19  DC  D "O5'" 1 
ATOM   8043 C  "C5'" . DC  D 4 18  ? 40.16100  30.99200  31.17700  1.000 320.79000 ? 19  DC  D "C5'" 1 
ATOM   8044 C  "C4'" . DC  D 4 18  ? 39.50200  32.25900  30.65400  1.000 312.76000 ? 19  DC  D "C4'" 1 
ATOM   8045 O  "O4'" . DC  D 4 18  ? 40.31600  32.79500  29.56500  1.000 308.21000 ? 19  DC  D "O4'" 1 
ATOM   8046 C  "C3'" . DC  D 4 18  ? 38.12600  32.04600  30.05200  1.000 304.00000 ? 19  DC  D "C3'" 1 
ATOM   8047 O  "O3'" . DC  D 4 18  ? 37.07900  32.14300  31.02200  1.000 305.89000 ? 19  DC  D "O3'" 1 
ATOM   8048 C  "C2'" . DC  D 4 18  ? 38.07500  33.12100  28.97200  1.000 303.36000 ? 19  DC  D "C2'" 1 
ATOM   8049 C  "C1'" . DC  D 4 18  ? 39.50300  33.06800  28.44700  1.000 300.23000 ? 19  DC  D "C1'" 1 
ATOM   8050 N  N1    . DC  D 4 18  ? 39.74700  31.99000  27.35100  1.000 298.88000 ? 19  DC  D N1    1 
ATOM   8051 C  C2    . DC  D 4 18  ? 39.66200  32.34100  25.99600  1.000 304.95000 ? 19  DC  D C2    1 
ATOM   8052 O  O2    . DC  D 4 18  ? 39.36800  33.49800  25.69100  1.000 311.72000 ? 19  DC  D O2    1 
ATOM   8053 N  N3    . DC  D 4 18  ? 39.89700  31.39200  25.05800  1.000 300.76000 ? 19  DC  D N3    1 
ATOM   8054 C  C4    . DC  D 4 18  ? 40.21400  30.15800  25.42200  1.000 300.79000 ? 19  DC  D C4    1 
ATOM   8055 N  N4    . DC  D 4 18  ? 40.43400  29.27400  24.46700  1.000 298.88000 ? 19  DC  D N4    1 
ATOM   8056 C  C5    . DC  D 4 18  ? 40.31200  29.77000  26.77300  1.000 300.89000 ? 19  DC  D C5    1 
ATOM   8057 C  C6    . DC  D 4 18  ? 40.08600  30.70000  27.69600  1.000 294.30000 ? 19  DC  D C6    1 
ATOM   8058 P  P     . DA  D 4 19  ? 36.94800  33.34000  32.09400  1.000 313.31000 ? 20  DA  D P     1 
ATOM   8059 O  OP1   . DA  D 4 19  ? 37.79800  34.51700  31.80700  1.000 312.73000 ? 20  DA  D OP1   1 
ATOM   8060 O  OP2   . DA  D 4 19  ? 37.08900  32.57900  33.36200  1.000 309.70000 ? 20  DA  D OP2   1 
ATOM   8061 O  "O5'" . DA  D 4 19  ? 35.45700  33.85500  31.82600  1.000 312.42000 ? 20  DA  D "O5'" 1 
ATOM   8062 C  "C5'" . DA  D 4 19  ? 34.72100  33.25900  30.74000  1.000 314.70000 ? 20  DA  D "C5'" 1 
ATOM   8063 C  "C4'" . DA  D 4 19  ? 33.88500  34.29300  30.03500  1.000 310.84000 ? 20  DA  D "C4'" 1 
ATOM   8064 O  "O4'" . DA  D 4 19  ? 33.46200  35.24900  30.98400  1.000 312.27000 ? 20  DA  D "O4'" 1 
ATOM   8065 C  "C3'" . DA  D 4 19  ? 34.57000  35.13000  28.95900  1.000 309.58000 ? 20  DA  D "C3'" 1 
ATOM   8066 O  "O3'" . DA  D 4 19  ? 34.31500  34.62400  27.63200  1.000 306.22000 ? 20  DA  D "O3'" 1 
ATOM   8067 C  "C2'" . DA  D 4 19  ? 33.99800  36.54300  29.12500  1.000 312.73000 ? 20  DA  D "C2'" 1 
ATOM   8068 C  "C1'" . DA  D 4 19  ? 33.05300  36.39300  30.30000  1.000 312.24000 ? 20  DA  D "C1'" 1 
ATOM   8069 N  N9    . DA  D 4 19  ? 33.07200  37.50000  31.24400  1.000 317.26000 ? 20  DA  D N9    1 
ATOM   8070 C  C8    . DA  D 4 19  ? 32.03300  37.86800  32.01300  1.000 315.42000 ? 20  DA  D C8    1 
ATOM   8071 N  N7    . DA  D 4 19  ? 32.29300  38.86500  32.79300  1.000 316.63000 ? 20  DA  D N7    1 
ATOM   8072 C  C5    . DA  D 4 19  ? 33.59300  39.18300  32.53400  1.000 318.47000 ? 20  DA  D C5    1 
ATOM   8073 C  C6    . DA  D 4 19  ? 34.44800  40.17100  33.06000  1.000 317.86000 ? 20  DA  D C6    1 
ATOM   8074 N  N6    . DA  D 4 19  ? 34.07800  41.03400  33.99600  1.000 321.09000 ? 20  DA  D N6    1 
ATOM   8075 N  N1    . DA  D 4 19  ? 35.69900  40.23700  32.57000  1.000 322.51000 ? 20  DA  D N1    1 
ATOM   8076 C  C2    . DA  D 4 19  ? 36.10000  39.31900  31.67500  1.000 322.18000 ? 20  DA  D C2    1 
ATOM   8077 N  N3    . DA  D 4 19  ? 35.37800  38.37500  31.07000  1.000 313.87000 ? 20  DA  D N3    1 
ATOM   8078 C  C4    . DA  D 4 19  ? 34.11600  38.34700  31.57600  1.000 318.20000 ? 20  DA  D C4    1 
ATOM   8079 P  P     . DT  D 4 20  ? 32.95900  33.85800  27.21100  1.000 284.85000 ? 21  DT  D P     1 
ATOM   8080 O  OP1   . DT  D 4 20  ? 32.84400  34.50800  25.88500  1.000 295.24000 ? 21  DT  D OP1   1 
ATOM   8081 O  OP2   . DT  D 4 20  ? 31.83900  33.91700  28.18600  1.000 287.89000 ? 21  DT  D OP2   1 
ATOM   8082 O  "O5'" . DT  D 4 20  ? 33.48900  32.36200  26.99400  1.000 293.56000 ? 21  DT  D "O5'" 1 
ATOM   8083 C  "C5'" . DT  D 4 20  ? 32.69000  31.25000  27.23400  1.000 285.57000 ? 21  DT  D "C5'" 1 
ATOM   8084 C  "C4'" . DT  D 4 20  ? 33.49500  30.00300  26.91200  1.000 289.83000 ? 21  DT  D "C4'" 1 
ATOM   8085 O  "O4'" . DT  D 4 20  ? 34.00900  30.10600  25.55900  1.000 289.59000 ? 21  DT  D "O4'" 1 
ATOM   8086 C  "C3'" . DT  D 4 20  ? 34.71800  29.77300  27.80700  1.000 297.10000 ? 21  DT  D "C3'" 1 
ATOM   8087 O  "O3'" . DT  D 4 20  ? 34.78500  28.41200  28.18900  1.000 294.53000 ? 21  DT  D "O3'" 1 
ATOM   8088 C  "C2'" . DT  D 4 20  ? 35.90200  30.16400  26.92100  1.000 296.86000 ? 21  DT  D "C2'" 1 
ATOM   8089 C  "C1'" . DT  D 4 20  ? 35.39400  29.81900  25.53900  1.000 288.30000 ? 21  DT  D "C1'" 1 
ATOM   8090 N  N1    . DT  D 4 20  ? 35.98100  30.66100  24.48800  1.000 289.69000 ? 21  DT  D N1    1 
ATOM   8091 C  C2    . DT  D 4 20  ? 36.54000  30.08900  23.37000  1.000 298.23000 ? 21  DT  D C2    1 
ATOM   8092 O  O2    . DT  D 4 20  ? 36.61800  28.88100  23.19400  1.000 306.65000 ? 21  DT  D O2    1 
ATOM   8093 N  N3    . DT  D 4 20  ? 37.01900  30.98600  22.46200  1.000 293.59000 ? 21  DT  D N3    1 
ATOM   8094 C  C4    . DT  D 4 20  ? 36.98800  32.35600  22.55600  1.000 301.44000 ? 21  DT  D C4    1 
ATOM   8095 O  O4    . DT  D 4 20  ? 37.43900  33.08400  21.69500  1.000 294.44000 ? 21  DT  D O4    1 
ATOM   8096 C  C5    . DT  D 4 20  ? 36.37900  32.88400  23.74800  1.000 306.42000 ? 21  DT  D C5    1 
ATOM   8097 C  C7    . DT  D 4 20  ? 36.27800  34.36700  23.97500  1.000 302.79000 ? 21  DT  D C7    1 
ATOM   8098 C  C6    . DT  D 4 20  ? 35.90700  32.01800  24.63900  1.000 291.04000 ? 21  DT  D C6    1 
HETATM 8099 MG MG    . MG  E 5 .   ? 38.08900  27.37700  28.49400  1.000 30.00000  ? 101 MG  D MG    1 
# 
