data_9L6Y
# 
_entry.id   9L6Y 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9L6Y         pdb_00009l6y 10.2210/pdb9l6y/pdb 
WWPDB D_1300055072 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-04-02 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9L6Y 
_pdbx_database_status.recvd_initial_deposition_date   2024-12-25 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              kakuta@agr.kyushu-u.ac.jp 
_pdbx_contact_author.name_first         Yoshimitsu 
_pdbx_contact_author.name_last          Kakuta 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-0781-2074 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Teramoto, T.'    1 0000-0003-1555-5394 
'Nakashima, M.'   2 ?                   
'Fukunaga, K.'    3 ?                   
'Yokobayashi, Y.' 4 ?                   
'Kakuta, Y.'      5 ?                   
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nucleic Acids Res.' 
_citation.journal_id_ASTM           NARHAD 
_citation.journal_id_CSD            0389 
_citation.journal_id_ISSN           1362-4962 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            53 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Structural insights into lab-coevolved RNA-RBP pairs and applications of synthetic riboswitches in cell-free system.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1093/nar/gkaf212 
_citation.pdbx_database_id_PubMed   40119732 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Fukunaga, K.'    1 0000-0002-4259-4359 
primary 'Teramoto, T.'    2 0000-0003-1555-5394 
primary 'Nakashima, M.'   3 ?                   
primary 'Ohtani, T.'      4 ?                   
primary 'Katsuki, R.'     5 ?                   
primary 'Matsuura, T.'    6 0000-0003-1015-6781 
primary 'Yokobayashi, Y.' 7 0000-0002-2417-1934 
primary 'Kakuta, Y.'      8 0000-0002-0781-2074 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Large ribosomal subunit protein eL8' 13100.113 2 ? ? ? ? 
2 polymer     syn 'CS2 RNA'                             10655.442 2 ? ? ? ? 
3 non-polymer syn 'CALCIUM ION'                         40.078    5 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        '50S ribosomal protein L7Ae,Ribosomal protein L8e' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)'   no no 
;SYVRFEVPEDMQNEALSLLEKVRESGKVKKGTNSTTLAVSRGLAKLVYIAEDVDPPEIVAHLPLLCEEKNVPYIYVKSKN
DLGRAVGRVYPGASAAIINEGELRKELGSLVEKIKGLQK
;
;SYVRFEVPEDMQNEALSLLEKVRESGKVKKGTNSTTLAVSRGLAKLVYIAEDVDPPEIVAHLPLLCEEKNVPYIYVKSKN
DLGRAVGRVYPGASAAIINEGELRKELGSLVEKIKGLQK
;
A,C ? 
2 polyribonucleotide no no GGAUGCAGAGAACGAAAGUUCCAUGACGCAUCC GGAUGCAGAGAACGAAAGUUCCAUGACGCAUCC B,D ? 
# 
_pdbx_entity_nonpoly.entity_id   3 
_pdbx_entity_nonpoly.name        'CALCIUM ION' 
_pdbx_entity_nonpoly.comp_id     CA 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   SER n 
1 2   TYR n 
1 3   VAL n 
1 4   ARG n 
1 5   PHE n 
1 6   GLU n 
1 7   VAL n 
1 8   PRO n 
1 9   GLU n 
1 10  ASP n 
1 11  MET n 
1 12  GLN n 
1 13  ASN n 
1 14  GLU n 
1 15  ALA n 
1 16  LEU n 
1 17  SER n 
1 18  LEU n 
1 19  LEU n 
1 20  GLU n 
1 21  LYS n 
1 22  VAL n 
1 23  ARG n 
1 24  GLU n 
1 25  SER n 
1 26  GLY n 
1 27  LYS n 
1 28  VAL n 
1 29  LYS n 
1 30  LYS n 
1 31  GLY n 
1 32  THR n 
1 33  ASN n 
1 34  SER n 
1 35  THR n 
1 36  THR n 
1 37  LEU n 
1 38  ALA n 
1 39  VAL n 
1 40  SER n 
1 41  ARG n 
1 42  GLY n 
1 43  LEU n 
1 44  ALA n 
1 45  LYS n 
1 46  LEU n 
1 47  VAL n 
1 48  TYR n 
1 49  ILE n 
1 50  ALA n 
1 51  GLU n 
1 52  ASP n 
1 53  VAL n 
1 54  ASP n 
1 55  PRO n 
1 56  PRO n 
1 57  GLU n 
1 58  ILE n 
1 59  VAL n 
1 60  ALA n 
1 61  HIS n 
1 62  LEU n 
1 63  PRO n 
1 64  LEU n 
1 65  LEU n 
1 66  CYS n 
1 67  GLU n 
1 68  GLU n 
1 69  LYS n 
1 70  ASN n 
1 71  VAL n 
1 72  PRO n 
1 73  TYR n 
1 74  ILE n 
1 75  TYR n 
1 76  VAL n 
1 77  LYS n 
1 78  SER n 
1 79  LYS n 
1 80  ASN n 
1 81  ASP n 
1 82  LEU n 
1 83  GLY n 
1 84  ARG n 
1 85  ALA n 
1 86  VAL n 
1 87  GLY n 
1 88  ARG n 
1 89  VAL n 
1 90  TYR n 
1 91  PRO n 
1 92  GLY n 
1 93  ALA n 
1 94  SER n 
1 95  ALA n 
1 96  ALA n 
1 97  ILE n 
1 98  ILE n 
1 99  ASN n 
1 100 GLU n 
1 101 GLY n 
1 102 GLU n 
1 103 LEU n 
1 104 ARG n 
1 105 LYS n 
1 106 GLU n 
1 107 LEU n 
1 108 GLY n 
1 109 SER n 
1 110 LEU n 
1 111 VAL n 
1 112 GLU n 
1 113 LYS n 
1 114 ILE n 
1 115 LYS n 
1 116 GLY n 
1 117 LEU n 
1 118 GLN n 
1 119 LYS n 
2 1   G   n 
2 2   G   n 
2 3   A   n 
2 4   U   n 
2 5   G   n 
2 6   C   n 
2 7   A   n 
2 8   G   n 
2 9   A   n 
2 10  G   n 
2 11  A   n 
2 12  A   n 
2 13  C   n 
2 14  G   n 
2 15  A   n 
2 16  A   n 
2 17  A   n 
2 18  G   n 
2 19  U   n 
2 20  U   n 
2 21  C   n 
2 22  C   n 
2 23  A   n 
2 24  U   n 
2 25  G   n 
2 26  A   n 
2 27  C   n 
2 28  G   n 
2 29  C   n 
2 30  A   n 
2 31  U   n 
2 32  C   n 
2 33  C   n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   119 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'rpl7ae, AF_0764' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      
'Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     224325 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
_pdbx_entity_src_syn.entity_id              2 
_pdbx_entity_src_syn.pdbx_src_id            1 
_pdbx_entity_src_syn.pdbx_alt_source_flag   sample 
_pdbx_entity_src_syn.pdbx_beg_seq_num       1 
_pdbx_entity_src_syn.pdbx_end_seq_num       33 
_pdbx_entity_src_syn.organism_scientific    'synthetic construct' 
_pdbx_entity_src_syn.organism_common_name   ? 
_pdbx_entity_src_syn.ncbi_taxonomy_id       32630 
_pdbx_entity_src_syn.details                ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A   'RNA linking'       y "ADENOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O7 P' 347.221 
ALA 'L-peptide linking' y ALANINE                      ? 'C3 H7 N O2'      89.093  
ARG 'L-peptide linking' y ARGININE                     ? 'C6 H15 N4 O2 1'  175.209 
ASN 'L-peptide linking' y ASPARAGINE                   ? 'C4 H8 N2 O3'     132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'              ? 'C4 H7 N O4'      133.103 
C   'RNA linking'       y "CYTIDINE-5'-MONOPHOSPHATE"  ? 'C9 H14 N3 O8 P'  323.197 
CA  non-polymer         . 'CALCIUM ION'                ? 'Ca 2'            40.078  
CYS 'L-peptide linking' y CYSTEINE                     ? 'C3 H7 N O2 S'    121.158 
G   'RNA linking'       y "GUANOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O8 P' 363.221 
GLN 'L-peptide linking' y GLUTAMINE                    ? 'C5 H10 N2 O3'    146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'              ? 'C5 H9 N O4'      147.129 
GLY 'peptide linking'   y GLYCINE                      ? 'C2 H5 N O2'      75.067  
HIS 'L-peptide linking' y HISTIDINE                    ? 'C6 H10 N3 O2 1'  156.162 
ILE 'L-peptide linking' y ISOLEUCINE                   ? 'C6 H13 N O2'     131.173 
LEU 'L-peptide linking' y LEUCINE                      ? 'C6 H13 N O2'     131.173 
LYS 'L-peptide linking' y LYSINE                       ? 'C6 H15 N2 O2 1'  147.195 
MET 'L-peptide linking' y METHIONINE                   ? 'C5 H11 N O2 S'   149.211 
PHE 'L-peptide linking' y PHENYLALANINE                ? 'C9 H11 N O2'     165.189 
PRO 'L-peptide linking' y PROLINE                      ? 'C5 H9 N O2'      115.130 
SER 'L-peptide linking' y SERINE                       ? 'C3 H7 N O3'      105.093 
THR 'L-peptide linking' y THREONINE                    ? 'C4 H9 N O3'      119.119 
TYR 'L-peptide linking' y TYROSINE                     ? 'C9 H11 N O3'     181.189 
U   'RNA linking'       y "URIDINE-5'-MONOPHOSPHATE"   ? 'C9 H13 N2 O9 P'  324.181 
VAL 'L-peptide linking' y VALINE                       ? 'C5 H11 N O2'     117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   SER 1   1   ?   ?   ?   A . n 
A 1 2   TYR 2   2   2   TYR TYR A . n 
A 1 3   VAL 3   3   3   VAL VAL A . n 
A 1 4   ARG 4   4   4   ARG ARG A . n 
A 1 5   PHE 5   5   5   PHE PHE A . n 
A 1 6   GLU 6   6   6   GLU GLU A . n 
A 1 7   VAL 7   7   7   VAL VAL A . n 
A 1 8   PRO 8   8   8   PRO PRO A . n 
A 1 9   GLU 9   9   9   GLU GLU A . n 
A 1 10  ASP 10  10  10  ASP ASP A . n 
A 1 11  MET 11  11  11  MET MET A . n 
A 1 12  GLN 12  12  12  GLN GLN A . n 
A 1 13  ASN 13  13  13  ASN ASN A . n 
A 1 14  GLU 14  14  14  GLU GLU A . n 
A 1 15  ALA 15  15  15  ALA ALA A . n 
A 1 16  LEU 16  16  16  LEU LEU A . n 
A 1 17  SER 17  17  17  SER SER A . n 
A 1 18  LEU 18  18  18  LEU LEU A . n 
A 1 19  LEU 19  19  19  LEU LEU A . n 
A 1 20  GLU 20  20  20  GLU GLU A . n 
A 1 21  LYS 21  21  21  LYS LYS A . n 
A 1 22  VAL 22  22  22  VAL VAL A . n 
A 1 23  ARG 23  23  23  ARG ARG A . n 
A 1 24  GLU 24  24  24  GLU GLU A . n 
A 1 25  SER 25  25  25  SER SER A . n 
A 1 26  GLY 26  26  26  GLY GLY A . n 
A 1 27  LYS 27  27  27  LYS LYS A . n 
A 1 28  VAL 28  28  28  VAL VAL A . n 
A 1 29  LYS 29  29  29  LYS LYS A . n 
A 1 30  LYS 30  30  30  LYS LYS A . n 
A 1 31  GLY 31  31  31  GLY GLY A . n 
A 1 32  THR 32  32  32  THR THR A . n 
A 1 33  ASN 33  33  33  ASN ASN A . n 
A 1 34  SER 34  34  34  SER SER A . n 
A 1 35  THR 35  35  35  THR THR A . n 
A 1 36  THR 36  36  36  THR THR A . n 
A 1 37  LEU 37  37  37  LEU LEU A . n 
A 1 38  ALA 38  38  38  ALA ALA A . n 
A 1 39  VAL 39  39  39  VAL VAL A . n 
A 1 40  SER 40  40  40  SER SER A . n 
A 1 41  ARG 41  41  41  ARG ARG A . n 
A 1 42  GLY 42  42  42  GLY GLY A . n 
A 1 43  LEU 43  43  43  LEU LEU A . n 
A 1 44  ALA 44  44  44  ALA ALA A . n 
A 1 45  LYS 45  45  45  LYS LYS A . n 
A 1 46  LEU 46  46  46  LEU LEU A . n 
A 1 47  VAL 47  47  47  VAL VAL A . n 
A 1 48  TYR 48  48  48  TYR TYR A . n 
A 1 49  ILE 49  49  49  ILE ILE A . n 
A 1 50  ALA 50  50  50  ALA ALA A . n 
A 1 51  GLU 51  51  51  GLU GLU A . n 
A 1 52  ASP 52  52  52  ASP ASP A . n 
A 1 53  VAL 53  53  53  VAL VAL A . n 
A 1 54  ASP 54  54  54  ASP ASP A . n 
A 1 55  PRO 55  55  55  PRO PRO A . n 
A 1 56  PRO 56  56  56  PRO PRO A . n 
A 1 57  GLU 57  57  57  GLU GLU A . n 
A 1 58  ILE 58  58  58  ILE ILE A . n 
A 1 59  VAL 59  59  59  VAL VAL A . n 
A 1 60  ALA 60  60  60  ALA ALA A . n 
A 1 61  HIS 61  61  61  HIS HIS A . n 
A 1 62  LEU 62  62  62  LEU LEU A . n 
A 1 63  PRO 63  63  63  PRO PRO A . n 
A 1 64  LEU 64  64  64  LEU LEU A . n 
A 1 65  LEU 65  65  65  LEU LEU A . n 
A 1 66  CYS 66  66  66  CYS CYS A . n 
A 1 67  GLU 67  67  67  GLU GLU A . n 
A 1 68  GLU 68  68  68  GLU GLU A . n 
A 1 69  LYS 69  69  69  LYS LYS A . n 
A 1 70  ASN 70  70  70  ASN ASN A . n 
A 1 71  VAL 71  71  71  VAL VAL A . n 
A 1 72  PRO 72  72  72  PRO PRO A . n 
A 1 73  TYR 73  73  73  TYR TYR A . n 
A 1 74  ILE 74  74  74  ILE ILE A . n 
A 1 75  TYR 75  75  75  TYR TYR A . n 
A 1 76  VAL 76  76  76  VAL VAL A . n 
A 1 77  LYS 77  77  77  LYS LYS A . n 
A 1 78  SER 78  78  78  SER SER A . n 
A 1 79  LYS 79  79  79  LYS LYS A . n 
A 1 80  ASN 80  80  80  ASN ASN A . n 
A 1 81  ASP 81  81  81  ASP ASP A . n 
A 1 82  LEU 82  82  82  LEU LEU A . n 
A 1 83  GLY 83  83  83  GLY GLY A . n 
A 1 84  ARG 84  84  84  ARG ARG A . n 
A 1 85  ALA 85  85  85  ALA ALA A . n 
A 1 86  VAL 86  86  86  VAL VAL A . n 
A 1 87  GLY 87  87  87  GLY GLY A . n 
A 1 88  ARG 88  88  88  ARG ARG A . n 
A 1 89  VAL 89  89  89  VAL VAL A . n 
A 1 90  TYR 90  90  90  TYR TYR A . n 
A 1 91  PRO 91  91  91  PRO PRO A . n 
A 1 92  GLY 92  92  92  GLY GLY A . n 
A 1 93  ALA 93  93  93  ALA ALA A . n 
A 1 94  SER 94  94  94  SER SER A . n 
A 1 95  ALA 95  95  95  ALA ALA A . n 
A 1 96  ALA 96  96  96  ALA ALA A . n 
A 1 97  ILE 97  97  97  ILE ILE A . n 
A 1 98  ILE 98  98  98  ILE ILE A . n 
A 1 99  ASN 99  99  99  ASN ASN A . n 
A 1 100 GLU 100 100 100 GLU GLU A . n 
A 1 101 GLY 101 101 101 GLY GLY A . n 
A 1 102 GLU 102 102 102 GLU GLU A . n 
A 1 103 LEU 103 103 103 LEU LEU A . n 
A 1 104 ARG 104 104 104 ARG ARG A . n 
A 1 105 LYS 105 105 105 LYS LYS A . n 
A 1 106 GLU 106 106 106 GLU GLU A . n 
A 1 107 LEU 107 107 107 LEU LEU A . n 
A 1 108 GLY 108 108 108 GLY GLY A . n 
A 1 109 SER 109 109 109 SER SER A . n 
A 1 110 LEU 110 110 110 LEU LEU A . n 
A 1 111 VAL 111 111 111 VAL VAL A . n 
A 1 112 GLU 112 112 112 GLU GLU A . n 
A 1 113 LYS 113 113 113 LYS LYS A . n 
A 1 114 ILE 114 114 114 ILE ILE A . n 
A 1 115 LYS 115 115 115 LYS LYS A . n 
A 1 116 GLY 116 116 116 GLY GLY A . n 
A 1 117 LEU 117 117 117 LEU LEU A . n 
A 1 118 GLN 118 118 118 GLN GLN A . n 
A 1 119 LYS 119 119 ?   ?   ?   A . n 
B 2 1   G   1   1   1   G   G   B . n 
B 2 2   G   2   2   2   G   G   B . n 
B 2 3   A   3   3   3   A   A   B . n 
B 2 4   U   4   4   4   U   U   B . n 
B 2 5   G   5   5   5   G   G   B . n 
B 2 6   C   6   6   6   C   C   B . n 
B 2 7   A   7   7   7   A   A   B . n 
B 2 8   G   8   8   8   G   G   B . n 
B 2 9   A   9   9   9   A   A   B . n 
B 2 10  G   10  10  10  G   G   B . n 
B 2 11  A   11  11  11  A   A   B . n 
B 2 12  A   12  12  12  A   A   B . n 
B 2 13  C   13  13  13  C   C   B . n 
B 2 14  G   14  14  14  G   G   B . n 
B 2 15  A   15  15  15  A   A   B . n 
B 2 16  A   16  16  16  A   A   B . n 
B 2 17  A   17  17  17  A   A   B . n 
B 2 18  G   18  18  18  G   G   B . n 
B 2 19  U   19  19  19  U   U   B . n 
B 2 20  U   20  20  20  U   U   B . n 
B 2 21  C   21  21  21  C   C   B . n 
B 2 22  C   22  22  22  C   C   B . n 
B 2 23  A   23  23  23  A   A   B . n 
B 2 24  U   24  24  24  U   U   B . n 
B 2 25  G   25  25  25  G   G   B . n 
B 2 26  A   26  26  26  A   A   B . n 
B 2 27  C   27  27  27  C   C   B . n 
B 2 28  G   28  28  28  G   G   B . n 
B 2 29  C   29  29  29  C   C   B . n 
B 2 30  A   30  30  30  A   A   B . n 
B 2 31  U   31  31  31  U   U   B . n 
B 2 32  C   32  32  32  C   C   B . n 
B 2 33  C   33  33  33  C   C   B . n 
C 1 1   SER 1   1   ?   ?   ?   C . n 
C 1 2   TYR 2   2   2   TYR TYR C . n 
C 1 3   VAL 3   3   3   VAL VAL C . n 
C 1 4   ARG 4   4   4   ARG ARG C . n 
C 1 5   PHE 5   5   5   PHE PHE C . n 
C 1 6   GLU 6   6   6   GLU GLU C . n 
C 1 7   VAL 7   7   7   VAL VAL C . n 
C 1 8   PRO 8   8   8   PRO PRO C . n 
C 1 9   GLU 9   9   9   GLU GLU C . n 
C 1 10  ASP 10  10  10  ASP ASP C . n 
C 1 11  MET 11  11  11  MET MET C . n 
C 1 12  GLN 12  12  12  GLN GLN C . n 
C 1 13  ASN 13  13  13  ASN ASN C . n 
C 1 14  GLU 14  14  14  GLU GLU C . n 
C 1 15  ALA 15  15  15  ALA ALA C . n 
C 1 16  LEU 16  16  16  LEU LEU C . n 
C 1 17  SER 17  17  17  SER SER C . n 
C 1 18  LEU 18  18  18  LEU LEU C . n 
C 1 19  LEU 19  19  19  LEU LEU C . n 
C 1 20  GLU 20  20  20  GLU GLU C . n 
C 1 21  LYS 21  21  21  LYS LYS C . n 
C 1 22  VAL 22  22  22  VAL VAL C . n 
C 1 23  ARG 23  23  23  ARG ARG C . n 
C 1 24  GLU 24  24  24  GLU GLU C . n 
C 1 25  SER 25  25  25  SER SER C . n 
C 1 26  GLY 26  26  26  GLY GLY C . n 
C 1 27  LYS 27  27  27  LYS LYS C . n 
C 1 28  VAL 28  28  28  VAL VAL C . n 
C 1 29  LYS 29  29  29  LYS LYS C . n 
C 1 30  LYS 30  30  30  LYS LYS C . n 
C 1 31  GLY 31  31  31  GLY GLY C . n 
C 1 32  THR 32  32  32  THR THR C . n 
C 1 33  ASN 33  33  33  ASN ASN C . n 
C 1 34  SER 34  34  34  SER SER C . n 
C 1 35  THR 35  35  35  THR THR C . n 
C 1 36  THR 36  36  36  THR THR C . n 
C 1 37  LEU 37  37  37  LEU LEU C . n 
C 1 38  ALA 38  38  38  ALA ALA C . n 
C 1 39  VAL 39  39  39  VAL VAL C . n 
C 1 40  SER 40  40  40  SER SER C . n 
C 1 41  ARG 41  41  41  ARG ARG C . n 
C 1 42  GLY 42  42  42  GLY GLY C . n 
C 1 43  LEU 43  43  43  LEU LEU C . n 
C 1 44  ALA 44  44  44  ALA ALA C . n 
C 1 45  LYS 45  45  45  LYS LYS C . n 
C 1 46  LEU 46  46  46  LEU LEU C . n 
C 1 47  VAL 47  47  47  VAL VAL C . n 
C 1 48  TYR 48  48  48  TYR TYR C . n 
C 1 49  ILE 49  49  49  ILE ILE C . n 
C 1 50  ALA 50  50  50  ALA ALA C . n 
C 1 51  GLU 51  51  51  GLU GLU C . n 
C 1 52  ASP 52  52  52  ASP ASP C . n 
C 1 53  VAL 53  53  53  VAL VAL C . n 
C 1 54  ASP 54  54  54  ASP ASP C . n 
C 1 55  PRO 55  55  55  PRO PRO C . n 
C 1 56  PRO 56  56  56  PRO PRO C . n 
C 1 57  GLU 57  57  57  GLU GLU C . n 
C 1 58  ILE 58  58  58  ILE ILE C . n 
C 1 59  VAL 59  59  59  VAL VAL C . n 
C 1 60  ALA 60  60  60  ALA ALA C . n 
C 1 61  HIS 61  61  61  HIS HIS C . n 
C 1 62  LEU 62  62  62  LEU LEU C . n 
C 1 63  PRO 63  63  63  PRO PRO C . n 
C 1 64  LEU 64  64  64  LEU LEU C . n 
C 1 65  LEU 65  65  65  LEU LEU C . n 
C 1 66  CYS 66  66  66  CYS CYS C . n 
C 1 67  GLU 67  67  67  GLU GLU C . n 
C 1 68  GLU 68  68  68  GLU GLU C . n 
C 1 69  LYS 69  69  69  LYS LYS C . n 
C 1 70  ASN 70  70  70  ASN ASN C . n 
C 1 71  VAL 71  71  71  VAL VAL C . n 
C 1 72  PRO 72  72  72  PRO PRO C . n 
C 1 73  TYR 73  73  73  TYR TYR C . n 
C 1 74  ILE 74  74  74  ILE ILE C . n 
C 1 75  TYR 75  75  75  TYR TYR C . n 
C 1 76  VAL 76  76  76  VAL VAL C . n 
C 1 77  LYS 77  77  77  LYS LYS C . n 
C 1 78  SER 78  78  78  SER SER C . n 
C 1 79  LYS 79  79  79  LYS LYS C . n 
C 1 80  ASN 80  80  80  ASN ASN C . n 
C 1 81  ASP 81  81  81  ASP ASP C . n 
C 1 82  LEU 82  82  82  LEU LEU C . n 
C 1 83  GLY 83  83  83  GLY GLY C . n 
C 1 84  ARG 84  84  84  ARG ARG C . n 
C 1 85  ALA 85  85  85  ALA ALA C . n 
C 1 86  VAL 86  86  86  VAL VAL C . n 
C 1 87  GLY 87  87  87  GLY GLY C . n 
C 1 88  ARG 88  88  88  ARG ARG C . n 
C 1 89  VAL 89  89  89  VAL VAL C . n 
C 1 90  TYR 90  90  90  TYR TYR C . n 
C 1 91  PRO 91  91  91  PRO PRO C . n 
C 1 92  GLY 92  92  92  GLY GLY C . n 
C 1 93  ALA 93  93  93  ALA ALA C . n 
C 1 94  SER 94  94  94  SER SER C . n 
C 1 95  ALA 95  95  95  ALA ALA C . n 
C 1 96  ALA 96  96  96  ALA ALA C . n 
C 1 97  ILE 97  97  97  ILE ILE C . n 
C 1 98  ILE 98  98  98  ILE ILE C . n 
C 1 99  ASN 99  99  99  ASN ASN C . n 
C 1 100 GLU 100 100 100 GLU GLU C . n 
C 1 101 GLY 101 101 101 GLY GLY C . n 
C 1 102 GLU 102 102 102 GLU GLU C . n 
C 1 103 LEU 103 103 103 LEU LEU C . n 
C 1 104 ARG 104 104 104 ARG ARG C . n 
C 1 105 LYS 105 105 105 LYS LYS C . n 
C 1 106 GLU 106 106 106 GLU GLU C . n 
C 1 107 LEU 107 107 107 LEU LEU C . n 
C 1 108 GLY 108 108 108 GLY GLY C . n 
C 1 109 SER 109 109 109 SER SER C . n 
C 1 110 LEU 110 110 110 LEU LEU C . n 
C 1 111 VAL 111 111 111 VAL VAL C . n 
C 1 112 GLU 112 112 112 GLU GLU C . n 
C 1 113 LYS 113 113 113 LYS LYS C . n 
C 1 114 ILE 114 114 114 ILE ILE C . n 
C 1 115 LYS 115 115 115 LYS LYS C . n 
C 1 116 GLY 116 116 116 GLY GLY C . n 
C 1 117 LEU 117 117 117 LEU LEU C . n 
C 1 118 GLN 118 118 ?   ?   ?   C . n 
C 1 119 LYS 119 119 ?   ?   ?   C . n 
D 2 1   G   1   1   ?   ?   ?   D . n 
D 2 2   G   2   2   2   G   G   D . n 
D 2 3   A   3   3   3   A   A   D . n 
D 2 4   U   4   4   4   U   U   D . n 
D 2 5   G   5   5   5   G   G   D . n 
D 2 6   C   6   6   6   C   C   D . n 
D 2 7   A   7   7   7   A   A   D . n 
D 2 8   G   8   8   8   G   G   D . n 
D 2 9   A   9   9   9   A   A   D . n 
D 2 10  G   10  10  10  G   G   D . n 
D 2 11  A   11  11  11  A   A   D . n 
D 2 12  A   12  12  12  A   A   D . n 
D 2 13  C   13  13  13  C   C   D . n 
D 2 14  G   14  14  14  G   G   D . n 
D 2 15  A   15  15  15  A   A   D . n 
D 2 16  A   16  16  16  A   A   D . n 
D 2 17  A   17  17  17  A   A   D . n 
D 2 18  G   18  18  18  G   G   D . n 
D 2 19  U   19  19  19  U   U   D . n 
D 2 20  U   20  20  20  U   U   D . n 
D 2 21  C   21  21  21  C   C   D . n 
D 2 22  C   22  22  22  C   C   D . n 
D 2 23  A   23  23  23  A   A   D . n 
D 2 24  U   24  24  24  U   U   D . n 
D 2 25  G   25  25  25  G   G   D . n 
D 2 26  A   26  26  26  A   A   D . n 
D 2 27  C   27  27  27  C   C   D . n 
D 2 28  G   28  28  28  G   G   D . n 
D 2 29  C   29  29  29  C   C   D . n 
D 2 30  A   30  30  30  A   A   D . n 
D 2 31  U   31  31  31  U   U   D . n 
D 2 32  C   32  32  32  C   C   D . n 
D 2 33  C   33  33  ?   ?   ?   D . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        CA 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   CA 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 3 CA 1 101 1 CA CA B . 
F 3 CA 1 102 4 CA CA B . 
G 3 CA 1 101 2 CA CA D . 
H 3 CA 1 102 3 CA CA D . 
I 3 CA 1 103 5 CA CA D . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 1 A GLU 6 ? CG  ? A GLU 6 CG  
2 1 Y 1 A GLU 6 ? CD  ? A GLU 6 CD  
3 1 Y 1 A GLU 6 ? OE1 ? A GLU 6 OE1 
4 1 Y 1 A GLU 6 ? OE2 ? A GLU 6 OE2 
5 1 Y 1 C GLU 6 ? CG  ? C GLU 6 CG  
6 1 Y 1 C GLU 6 ? CD  ? C GLU 6 CD  
7 1 Y 1 C GLU 6 ? OE1 ? C GLU 6 OE1 
8 1 Y 1 C GLU 6 ? OE2 ? C GLU 6 OE2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? '(1.20.1_4487: ???)' 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .                    2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .                    3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? .                    4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   106.39 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9L6Y 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     56.300 
_cell.length_a_esd                 ? 
_cell.length_b                     55.280 
_cell.length_b_esd                 ? 
_cell.length_c                     83.050 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9L6Y 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                4 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1 21 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9L6Y 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.61 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          52.87 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '40% PEG300, 100 mM Sodium cacodylate/HCl, pH 6.5, 200 mM Calcium acetate' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS3 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-05-30 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SPRING-8 BEAMLINE BL45XU' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL45XU 
_diffrn_source.pdbx_synchrotron_site       SPring-8 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9L6Y 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              3.12 
_reflns.d_resolution_low                               50.0 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     8762 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           98.0 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                4.0 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          8.13 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.17 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.993 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    3.12 
_reflns_shell.d_res_low                                     3.30 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           1.44 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             1433 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               1.128 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.615 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9L6Y 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            3.12 
_refine.ls_d_res_low                             45.42 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     8745 
_refine.ls_number_reflns_R_free                  877 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    98.12 
_refine.ls_percent_reflns_R_free                 10.03 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2237 
_refine.ls_R_factor_R_free                       0.2572 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2199 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.35 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      4BW0 
_refine.pdbx_stereochemistry_target_values       ML 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.10 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.90 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 29.13 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.44 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.pdbx_number_atoms_protein        1791 
_refine_hist.pdbx_number_atoms_nucleic_acid   1372 
_refine_hist.pdbx_number_atoms_ligand         5 
_refine_hist.number_atoms_solvent             0 
_refine_hist.number_atoms_total               3168 
_refine_hist.d_res_high                       3.12 
_refine_hist.d_res_low                        45.42 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.004  ? ?    ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.756  ? ?    ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 16.431 ? 1014 ? f_dihedral_angle_d ? ? 
'X-RAY DIFFRACTION' ? 0.043  ? 606  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.004  ? 378  ? f_plane_restr      ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 3.12 3.32  . . 146 1321 99.00 . . . . 0.3169 . . . . . . . . . . . 0.3506 
'X-RAY DIFFRACTION' 3.32 3.57  . . 141 1303 99.00 . . . . 0.2788 . . . . . . . . . . . 0.3447 
'X-RAY DIFFRACTION' 3.57 3.93  . . 150 1314 99.00 . . . . 0.2369 . . . . . . . . . . . 0.3189 
'X-RAY DIFFRACTION' 3.93 4.50  . . 145 1296 98.00 . . . . 0.1982 . . . . . . . . . . . 0.2490 
'X-RAY DIFFRACTION' 4.50 5.67  . . 146 1318 98.00 . . . . 0.1949 . . . . . . . . . . . 0.2194 
'X-RAY DIFFRACTION' 5.67 45.42 . . 149 1316 96.00 . . . . 0.2016 . . . . . . . . . . . 0.2147 
# 
_struct.entry_id                     9L6Y 
_struct.title                        
'Crystal structure of the L7Ae derivative protein LS12 in complex with its co-evolved target CS2 RNA' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9L6Y 
_struct_keywords.text            'Protein-RNA complex, RNA BINDING PROTEIN' 
_struct_keywords.pdbx_keywords   'RNA BINDING PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 1 ? 
D N N 2 ? 
E N N 3 ? 
F N N 3 ? 
G N N 3 ? 
H N N 3 ? 
I N N 3 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP RL7A_ARCFU O29494 ? 1 
;YVRFEVPEDMQNEALSLLEKVRESGKVKKGTNETTKAVERGLAKLVYIAEDVDPPEIVAHLPLLCEEKNVPYIYVKSKND
LGRAVGIEVPCASAAIINEGELRKELGSLVEKIKGLQK
;
2 
2 PDB 9L6Y       9L6Y   ? 2 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9L6Y A 2 ? 119 ? O29494 2 ? 119 ? 2 119 
2 2 9L6Y B 1 ? 33  ? 9L6Y   1 ? 33  ? 1 33  
3 1 9L6Y C 2 ? 119 ? O29494 2 ? 119 ? 2 119 
4 2 9L6Y D 1 ? 33  ? 9L6Y   1 ? 33  ? 1 33  
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9L6Y SER A 1  ? UNP O29494 ?   ?  'expression tag'      1  1  
1 9L6Y SER A 34 ? UNP O29494 GLU 34 'engineered mutation' 34 2  
1 9L6Y LEU A 37 ? UNP O29494 LYS 37 'engineered mutation' 37 3  
1 9L6Y SER A 40 ? UNP O29494 GLU 40 'engineered mutation' 40 4  
1 9L6Y ARG A 88 ? UNP O29494 ILE 88 'engineered mutation' 88 5  
1 9L6Y VAL A 89 ? UNP O29494 GLU 89 'engineered mutation' 89 6  
1 9L6Y TYR A 90 ? UNP O29494 VAL 90 'engineered mutation' 90 7  
1 9L6Y GLY A 92 ? UNP O29494 CYS 92 'engineered mutation' 92 8  
3 9L6Y SER C 1  ? UNP O29494 ?   ?  'expression tag'      1  9  
3 9L6Y SER C 34 ? UNP O29494 GLU 34 'engineered mutation' 34 10 
3 9L6Y LEU C 37 ? UNP O29494 LYS 37 'engineered mutation' 37 11 
3 9L6Y SER C 40 ? UNP O29494 GLU 40 'engineered mutation' 40 12 
3 9L6Y ARG C 88 ? UNP O29494 ILE 88 'engineered mutation' 88 13 
3 9L6Y VAL C 89 ? UNP O29494 GLU 89 'engineered mutation' 89 14 
3 9L6Y TYR C 90 ? UNP O29494 VAL 90 'engineered mutation' 90 15 
3 9L6Y GLY C 92 ? UNP O29494 CYS 92 'engineered mutation' 92 16 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_and_software_defined_assembly PISA dimeric 2 
2 author_and_software_defined_assembly PISA dimeric 2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 1380  ? 
1 MORE         -24   ? 
1 'SSA (A^2)'  11070 ? 
2 'ABSA (A^2)' 1380  ? 
2 MORE         -25   ? 
2 'SSA (A^2)'  10790 ? 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,B,E,F   
2 1 C,D,G,H,I 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 PRO A 8   ? GLY A 26  ? PRO A 8   GLY A 26  1 ? 19 
HELX_P HELX_P2  AA2 GLY A 31  ? ARG A 41  ? GLY A 31  ARG A 41  1 ? 11 
HELX_P HELX_P3  AA3 PRO A 55  ? VAL A 59  ? PRO A 55  VAL A 59  5 ? 5  
HELX_P HELX_P4  AA4 HIS A 61  ? ASN A 70  ? HIS A 61  ASN A 70  1 ? 10 
HELX_P HELX_P5  AA5 LYS A 79  ? GLY A 83  ? LYS A 79  GLY A 83  5 ? 5  
HELX_P HELX_P6  AA6 LEU A 103 ? LEU A 117 ? LEU A 103 LEU A 117 1 ? 15 
HELX_P HELX_P7  AA7 ASP C 10  ? VAL C 22  ? ASP C 10  VAL C 22  1 ? 13 
HELX_P HELX_P8  AA8 GLY C 31  ? ARG C 41  ? GLY C 31  ARG C 41  1 ? 11 
HELX_P HELX_P9  AA9 PRO C 55  ? VAL C 59  ? PRO C 55  VAL C 59  5 ? 5  
HELX_P HELX_P10 AB1 HIS C 61  ? ASN C 70  ? HIS C 61  ASN C 70  1 ? 10 
HELX_P HELX_P11 AB2 SER C 78  ? ALA C 85  ? SER C 78  ALA C 85  1 ? 8  
HELX_P HELX_P12 AB3 LEU C 103 ? LEU C 117 ? LEU C 103 LEU C 117 1 ? 15 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1  metalc ? ? B A 11 OP2 ? ? ? 1_555 E CA .  CA ? ? B A 11 B CA 101 1_555 ? ? ? ? ? ? ?             2.493 ? ? 
metalc2  metalc ? ? D A 11 OP2 ? ? ? 1_555 G CA .  CA ? ? D A 11 D CA 101 1_555 ? ? ? ? ? ? ?             2.543 ? ? 
metalc3  metalc ? ? D G 18 OP2 ? ? ? 1_555 H CA .  CA ? ? D G 18 D CA 102 1_555 ? ? ? ? ? ? ?             2.645 ? ? 
hydrog1  hydrog ? ? B G 1  N1  ? ? ? 1_555 B C  33 N3 ? ? B G 1  B C  33  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog2  hydrog ? ? B G 1  N2  ? ? ? 1_555 B C  33 O2 ? ? B G 1  B C  33  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog3  hydrog ? ? B G 1  O6  ? ? ? 1_555 B C  33 N4 ? ? B G 1  B C  33  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog4  hydrog ? ? B G 2  N1  ? ? ? 1_555 B C  32 N3 ? ? B G 2  B C  32  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog5  hydrog ? ? B G 2  N2  ? ? ? 1_555 B C  32 O2 ? ? B G 2  B C  32  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog6  hydrog ? ? B G 2  O6  ? ? ? 1_555 B C  32 N4 ? ? B G 2  B C  32  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog7  hydrog ? ? B A 3  N1  ? ? ? 1_555 B U  31 N3 ? ? B A 3  B U  31  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog8  hydrog ? ? B A 3  N6  ? ? ? 1_555 B U  31 O4 ? ? B A 3  B U  31  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog9  hydrog ? ? B U 4  N3  ? ? ? 1_555 B A  30 N1 ? ? B U 4  B A  30  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog10 hydrog ? ? B U 4  O4  ? ? ? 1_555 B A  30 N6 ? ? B U 4  B A  30  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog11 hydrog ? ? B G 5  N1  ? ? ? 1_555 B C  29 N3 ? ? B G 5  B C  29  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog12 hydrog ? ? B G 5  N2  ? ? ? 1_555 B C  29 O2 ? ? B G 5  B C  29  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog13 hydrog ? ? B G 5  O6  ? ? ? 1_555 B C  29 N4 ? ? B G 5  B C  29  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog14 hydrog ? ? B C 6  N3  ? ? ? 1_555 B G  28 N1 ? ? B C 6  B G  28  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog15 hydrog ? ? B C 6  N4  ? ? ? 1_555 B G  28 O6 ? ? B C 6  B G  28  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog16 hydrog ? ? B C 6  O2  ? ? ? 1_555 B G  28 N2 ? ? B C 6  B G  28  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog17 hydrog ? ? B A 7  N1  ? ? ? 1_555 B C  27 N4 ? ? B A 7  B C  27  1_555 ? ? ? ? ? ? 'A-C MISPAIR' ?     ? ? 
hydrog18 hydrog ? ? B G 8  N2  ? ? ? 1_555 B A  26 N7 ? ? B G 8  B A  26  1_555 ? ? ? ? ? ? 'G-A MISPAIR' ?     ? ? 
hydrog19 hydrog ? ? B A 9  N6  ? ? ? 1_555 B G  25 N3 ? ? B A 9  B G  25  1_555 ? ? ? ? ? ? TYPE_11_PAIR  ?     ? ? 
hydrog20 hydrog ? ? B A 9  N7  ? ? ? 1_555 B G  25 N2 ? ? B A 9  B G  25  1_555 ? ? ? ? ? ? TYPE_11_PAIR  ?     ? ? 
hydrog21 hydrog ? ? B G 10 N1  ? ? ? 1_555 B C  21 N3 ? ? B G 10 B C  21  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog22 hydrog ? ? B G 10 N2  ? ? ? 1_555 B C  21 O2 ? ? B G 10 B C  21  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog23 hydrog ? ? B G 10 O6  ? ? ? 1_555 B C  21 N4 ? ? B G 10 B C  21  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog24 hydrog ? ? B G 10 N2  ? ? ? 1_555 B A  26 N3 ? ? B G 10 B A  26  1_555 ? ? ? ? ? ? 'G-A MISPAIR' ?     ? ? 
hydrog25 hydrog ? ? B A 11 N1  ? ? ? 1_555 B U  20 N3 ? ? B A 11 B U  20  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog26 hydrog ? ? B A 11 N6  ? ? ? 1_555 B U  20 O4 ? ? B A 11 B U  20  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog27 hydrog ? ? B A 12 N1  ? ? ? 1_555 B U  19 N3 ? ? B A 12 B U  19  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog28 hydrog ? ? B A 12 N6  ? ? ? 1_555 B U  19 O4 ? ? B A 12 B U  19  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog29 hydrog ? ? B C 13 N3  ? ? ? 1_555 B G  18 N1 ? ? B C 13 B G  18  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog30 hydrog ? ? B C 13 N4  ? ? ? 1_555 B G  18 O6 ? ? B C 13 B G  18  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog31 hydrog ? ? B C 13 O2  ? ? ? 1_555 B G  18 N2 ? ? B C 13 B G  18  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog32 hydrog ? ? D G 2  N1  ? ? ? 1_555 D C  32 N3 ? ? D G 2  D C  32  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog33 hydrog ? ? D G 2  N2  ? ? ? 1_555 D C  32 O2 ? ? D G 2  D C  32  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog34 hydrog ? ? D G 2  O6  ? ? ? 1_555 D C  32 N4 ? ? D G 2  D C  32  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog35 hydrog ? ? D A 3  N1  ? ? ? 1_555 D U  31 N3 ? ? D A 3  D U  31  1_555 ? ? ? ? ? ? 'A-U PAIR'    ?     ? ? 
hydrog36 hydrog ? ? D U 4  N3  ? ? ? 1_555 D A  30 N1 ? ? D U 4  D A  30  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog37 hydrog ? ? D U 4  O4  ? ? ? 1_555 D A  30 N6 ? ? D U 4  D A  30  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog38 hydrog ? ? D G 5  N1  ? ? ? 1_555 D C  29 N3 ? ? D G 5  D C  29  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog39 hydrog ? ? D G 5  N2  ? ? ? 1_555 D C  29 O2 ? ? D G 5  D C  29  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog40 hydrog ? ? D G 5  O6  ? ? ? 1_555 D C  29 N4 ? ? D G 5  D C  29  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog41 hydrog ? ? D C 6  N3  ? ? ? 1_555 D G  28 N1 ? ? D C 6  D G  28  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog42 hydrog ? ? D C 6  N4  ? ? ? 1_555 D G  28 O6 ? ? D C 6  D G  28  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog43 hydrog ? ? D C 6  O2  ? ? ? 1_555 D G  28 N2 ? ? D C 6  D G  28  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog44 hydrog ? ? D A 7  N1  ? ? ? 1_555 D C  27 N4 ? ? D A 7  D C  27  1_555 ? ? ? ? ? ? 'A-C MISPAIR' ?     ? ? 
hydrog45 hydrog ? ? D G 8  N2  ? ? ? 1_555 D A  26 N7 ? ? D G 8  D A  26  1_555 ? ? ? ? ? ? 'G-A MISPAIR' ?     ? ? 
hydrog46 hydrog ? ? D A 9  N6  ? ? ? 1_555 D G  25 N3 ? ? D A 9  D G  25  1_555 ? ? ? ? ? ? TYPE_11_PAIR  ?     ? ? 
hydrog47 hydrog ? ? D A 9  N7  ? ? ? 1_555 D G  25 N2 ? ? D A 9  D G  25  1_555 ? ? ? ? ? ? TYPE_11_PAIR  ?     ? ? 
hydrog48 hydrog ? ? D G 10 N1  ? ? ? 1_555 D C  21 N3 ? ? D G 10 D C  21  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog49 hydrog ? ? D G 10 N2  ? ? ? 1_555 D C  21 O2 ? ? D G 10 D C  21  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog50 hydrog ? ? D G 10 O6  ? ? ? 1_555 D C  21 N4 ? ? D G 10 D C  21  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog51 hydrog ? ? D G 10 N2  ? ? ? 1_555 D A  26 N3 ? ? D G 10 D A  26  1_555 ? ? ? ? ? ? 'G-A MISPAIR' ?     ? ? 
hydrog52 hydrog ? ? D A 11 N1  ? ? ? 1_555 D U  20 N3 ? ? D A 11 D U  20  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog53 hydrog ? ? D A 11 N6  ? ? ? 1_555 D U  20 O4 ? ? D A 11 D U  20  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog54 hydrog ? ? D A 12 N1  ? ? ? 1_555 D U  19 N3 ? ? D A 12 D U  19  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog55 hydrog ? ? D A 12 N6  ? ? ? 1_555 D U  19 O4 ? ? D A 12 D U  19  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog56 hydrog ? ? D C 13 N3  ? ? ? 1_555 D G  18 N1 ? ? D C 13 D G  18  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog57 hydrog ? ? D C 13 N4  ? ? ? 1_555 D G  18 O6 ? ? D C 13 D G  18  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog58 hydrog ? ? D C 13 O2  ? ? ? 1_555 D G  18 N2 ? ? D C 13 D G  18  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
metalc ? ? 
hydrog ? ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 ASP 54 A . ? ASP 54 A PRO 55 A ? PRO 55 A 1 1.80 
2 ASP 54 C . ? ASP 54 C PRO 55 C ? PRO 55 C 1 1.12 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 LYS A 27 ? LYS A 30 ? LYS A 27 LYS A 30 
AA1 2 SER A 94 ? ASN A 99 ? SER A 94 ASN A 99 
AA1 3 LEU A 46 ? ALA A 50 ? LEU A 46 ALA A 50 
AA1 4 TYR A 73 ? VAL A 76 ? TYR A 73 VAL A 76 
AA2 1 LYS C 27 ? LYS C 30 ? LYS C 27 LYS C 30 
AA2 2 SER C 94 ? ASN C 99 ? SER C 94 ASN C 99 
AA2 3 LEU C 46 ? ALA C 50 ? LEU C 46 ALA C 50 
AA2 4 TYR C 73 ? VAL C 76 ? TYR C 73 VAL C 76 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N LYS A 29 ? N LYS A 29 O ALA A 96 ? O ALA A 96 
AA1 2 3 O ILE A 97 ? O ILE A 97 N LEU A 46 ? N LEU A 46 
AA1 3 4 N ILE A 49 ? N ILE A 49 O VAL A 76 ? O VAL A 76 
AA2 1 2 N LYS C 29 ? N LYS C 29 O ALA C 96 ? O ALA C 96 
AA2 2 3 O ILE C 97 ? O ILE C 97 N LEU C 46 ? N LEU C 46 
AA2 3 4 N ILE C 49 ? N ILE C 49 O VAL C 76 ? O VAL C 76 
# 
_pdbx_entry_details.entry_id                   9L6Y 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
_pdbx_validate_rmsd_angle.id                         1 
_pdbx_validate_rmsd_angle.PDB_model_num              1 
_pdbx_validate_rmsd_angle.auth_atom_id_1             C2 
_pdbx_validate_rmsd_angle.auth_asym_id_1             D 
_pdbx_validate_rmsd_angle.auth_comp_id_1             C 
_pdbx_validate_rmsd_angle.auth_seq_id_1              6 
_pdbx_validate_rmsd_angle.PDB_ins_code_1             ? 
_pdbx_validate_rmsd_angle.label_alt_id_1             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_2             N1 
_pdbx_validate_rmsd_angle.auth_asym_id_2             D 
_pdbx_validate_rmsd_angle.auth_comp_id_2             C 
_pdbx_validate_rmsd_angle.auth_seq_id_2              6 
_pdbx_validate_rmsd_angle.PDB_ins_code_2             ? 
_pdbx_validate_rmsd_angle.label_alt_id_2             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_3             "C1'" 
_pdbx_validate_rmsd_angle.auth_asym_id_3             D 
_pdbx_validate_rmsd_angle.auth_comp_id_3             C 
_pdbx_validate_rmsd_angle.auth_seq_id_3              6 
_pdbx_validate_rmsd_angle.PDB_ins_code_3             ? 
_pdbx_validate_rmsd_angle.label_alt_id_3             ? 
_pdbx_validate_rmsd_angle.angle_value                125.46 
_pdbx_validate_rmsd_angle.angle_target_value         118.80 
_pdbx_validate_rmsd_angle.angle_deviation            6.66 
_pdbx_validate_rmsd_angle.angle_standard_deviation   1.10 
_pdbx_validate_rmsd_angle.linker_flag                N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 ASP A 52 ? ? -100.07 48.55  
2 1 GLU C 24 ? ? -93.91  -61.30 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 A SER 1   ? A SER 1   
2 1 Y 1 A LYS 119 ? A LYS 119 
3 1 Y 1 C SER 1   ? C SER 1   
4 1 Y 1 C GLN 118 ? C GLN 118 
5 1 Y 1 C LYS 119 ? C LYS 119 
6 1 Y 1 D G   1   ? D G   1   
7 1 Y 1 D C   33  ? D C   33  
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A   OP3    O  N N 1   
A   P      P  N N 2   
A   OP1    O  N N 3   
A   OP2    O  N N 4   
A   "O5'"  O  N N 5   
A   "C5'"  C  N N 6   
A   "C4'"  C  N R 7   
A   "O4'"  O  N N 8   
A   "C3'"  C  N S 9   
A   "O3'"  O  N N 10  
A   "C2'"  C  N R 11  
A   "O2'"  O  N N 12  
A   "C1'"  C  N R 13  
A   N9     N  Y N 14  
A   C8     C  Y N 15  
A   N7     N  Y N 16  
A   C5     C  Y N 17  
A   C6     C  Y N 18  
A   N6     N  N N 19  
A   N1     N  Y N 20  
A   C2     C  Y N 21  
A   N3     N  Y N 22  
A   C4     C  Y N 23  
A   HOP3   H  N N 24  
A   HOP2   H  N N 25  
A   "H5'"  H  N N 26  
A   "H5''" H  N N 27  
A   "H4'"  H  N N 28  
A   "H3'"  H  N N 29  
A   "HO3'" H  N N 30  
A   "H2'"  H  N N 31  
A   "HO2'" H  N N 32  
A   "H1'"  H  N N 33  
A   H8     H  N N 34  
A   H61    H  N N 35  
A   H62    H  N N 36  
A   H2     H  N N 37  
ALA N      N  N N 38  
ALA CA     C  N S 39  
ALA C      C  N N 40  
ALA O      O  N N 41  
ALA CB     C  N N 42  
ALA OXT    O  N N 43  
ALA H      H  N N 44  
ALA H2     H  N N 45  
ALA HA     H  N N 46  
ALA HB1    H  N N 47  
ALA HB2    H  N N 48  
ALA HB3    H  N N 49  
ALA HXT    H  N N 50  
ARG N      N  N N 51  
ARG CA     C  N S 52  
ARG C      C  N N 53  
ARG O      O  N N 54  
ARG CB     C  N N 55  
ARG CG     C  N N 56  
ARG CD     C  N N 57  
ARG NE     N  N N 58  
ARG CZ     C  N N 59  
ARG NH1    N  N N 60  
ARG NH2    N  N N 61  
ARG OXT    O  N N 62  
ARG H      H  N N 63  
ARG H2     H  N N 64  
ARG HA     H  N N 65  
ARG HB2    H  N N 66  
ARG HB3    H  N N 67  
ARG HG2    H  N N 68  
ARG HG3    H  N N 69  
ARG HD2    H  N N 70  
ARG HD3    H  N N 71  
ARG HE     H  N N 72  
ARG HH11   H  N N 73  
ARG HH12   H  N N 74  
ARG HH21   H  N N 75  
ARG HH22   H  N N 76  
ARG HXT    H  N N 77  
ASN N      N  N N 78  
ASN CA     C  N S 79  
ASN C      C  N N 80  
ASN O      O  N N 81  
ASN CB     C  N N 82  
ASN CG     C  N N 83  
ASN OD1    O  N N 84  
ASN ND2    N  N N 85  
ASN OXT    O  N N 86  
ASN H      H  N N 87  
ASN H2     H  N N 88  
ASN HA     H  N N 89  
ASN HB2    H  N N 90  
ASN HB3    H  N N 91  
ASN HD21   H  N N 92  
ASN HD22   H  N N 93  
ASN HXT    H  N N 94  
ASP N      N  N N 95  
ASP CA     C  N S 96  
ASP C      C  N N 97  
ASP O      O  N N 98  
ASP CB     C  N N 99  
ASP CG     C  N N 100 
ASP OD1    O  N N 101 
ASP OD2    O  N N 102 
ASP OXT    O  N N 103 
ASP H      H  N N 104 
ASP H2     H  N N 105 
ASP HA     H  N N 106 
ASP HB2    H  N N 107 
ASP HB3    H  N N 108 
ASP HD2    H  N N 109 
ASP HXT    H  N N 110 
C   OP3    O  N N 111 
C   P      P  N N 112 
C   OP1    O  N N 113 
C   OP2    O  N N 114 
C   "O5'"  O  N N 115 
C   "C5'"  C  N N 116 
C   "C4'"  C  N R 117 
C   "O4'"  O  N N 118 
C   "C3'"  C  N S 119 
C   "O3'"  O  N N 120 
C   "C2'"  C  N R 121 
C   "O2'"  O  N N 122 
C   "C1'"  C  N R 123 
C   N1     N  N N 124 
C   C2     C  N N 125 
C   O2     O  N N 126 
C   N3     N  N N 127 
C   C4     C  N N 128 
C   N4     N  N N 129 
C   C5     C  N N 130 
C   C6     C  N N 131 
C   HOP3   H  N N 132 
C   HOP2   H  N N 133 
C   "H5'"  H  N N 134 
C   "H5''" H  N N 135 
C   "H4'"  H  N N 136 
C   "H3'"  H  N N 137 
C   "HO3'" H  N N 138 
C   "H2'"  H  N N 139 
C   "HO2'" H  N N 140 
C   "H1'"  H  N N 141 
C   H41    H  N N 142 
C   H42    H  N N 143 
C   H5     H  N N 144 
C   H6     H  N N 145 
CA  CA     CA N N 146 
CYS N      N  N N 147 
CYS CA     C  N R 148 
CYS C      C  N N 149 
CYS O      O  N N 150 
CYS CB     C  N N 151 
CYS SG     S  N N 152 
CYS OXT    O  N N 153 
CYS H      H  N N 154 
CYS H2     H  N N 155 
CYS HA     H  N N 156 
CYS HB2    H  N N 157 
CYS HB3    H  N N 158 
CYS HG     H  N N 159 
CYS HXT    H  N N 160 
G   OP3    O  N N 161 
G   P      P  N N 162 
G   OP1    O  N N 163 
G   OP2    O  N N 164 
G   "O5'"  O  N N 165 
G   "C5'"  C  N N 166 
G   "C4'"  C  N R 167 
G   "O4'"  O  N N 168 
G   "C3'"  C  N S 169 
G   "O3'"  O  N N 170 
G   "C2'"  C  N R 171 
G   "O2'"  O  N N 172 
G   "C1'"  C  N R 173 
G   N9     N  Y N 174 
G   C8     C  Y N 175 
G   N7     N  Y N 176 
G   C5     C  Y N 177 
G   C6     C  N N 178 
G   O6     O  N N 179 
G   N1     N  N N 180 
G   C2     C  N N 181 
G   N2     N  N N 182 
G   N3     N  N N 183 
G   C4     C  Y N 184 
G   HOP3   H  N N 185 
G   HOP2   H  N N 186 
G   "H5'"  H  N N 187 
G   "H5''" H  N N 188 
G   "H4'"  H  N N 189 
G   "H3'"  H  N N 190 
G   "HO3'" H  N N 191 
G   "H2'"  H  N N 192 
G   "HO2'" H  N N 193 
G   "H1'"  H  N N 194 
G   H8     H  N N 195 
G   H1     H  N N 196 
G   H21    H  N N 197 
G   H22    H  N N 198 
GLN N      N  N N 199 
GLN CA     C  N S 200 
GLN C      C  N N 201 
GLN O      O  N N 202 
GLN CB     C  N N 203 
GLN CG     C  N N 204 
GLN CD     C  N N 205 
GLN OE1    O  N N 206 
GLN NE2    N  N N 207 
GLN OXT    O  N N 208 
GLN H      H  N N 209 
GLN H2     H  N N 210 
GLN HA     H  N N 211 
GLN HB2    H  N N 212 
GLN HB3    H  N N 213 
GLN HG2    H  N N 214 
GLN HG3    H  N N 215 
GLN HE21   H  N N 216 
GLN HE22   H  N N 217 
GLN HXT    H  N N 218 
GLU N      N  N N 219 
GLU CA     C  N S 220 
GLU C      C  N N 221 
GLU O      O  N N 222 
GLU CB     C  N N 223 
GLU CG     C  N N 224 
GLU CD     C  N N 225 
GLU OE1    O  N N 226 
GLU OE2    O  N N 227 
GLU OXT    O  N N 228 
GLU H      H  N N 229 
GLU H2     H  N N 230 
GLU HA     H  N N 231 
GLU HB2    H  N N 232 
GLU HB3    H  N N 233 
GLU HG2    H  N N 234 
GLU HG3    H  N N 235 
GLU HE2    H  N N 236 
GLU HXT    H  N N 237 
GLY N      N  N N 238 
GLY CA     C  N N 239 
GLY C      C  N N 240 
GLY O      O  N N 241 
GLY OXT    O  N N 242 
GLY H      H  N N 243 
GLY H2     H  N N 244 
GLY HA2    H  N N 245 
GLY HA3    H  N N 246 
GLY HXT    H  N N 247 
HIS N      N  N N 248 
HIS CA     C  N S 249 
HIS C      C  N N 250 
HIS O      O  N N 251 
HIS CB     C  N N 252 
HIS CG     C  Y N 253 
HIS ND1    N  Y N 254 
HIS CD2    C  Y N 255 
HIS CE1    C  Y N 256 
HIS NE2    N  Y N 257 
HIS OXT    O  N N 258 
HIS H      H  N N 259 
HIS H2     H  N N 260 
HIS HA     H  N N 261 
HIS HB2    H  N N 262 
HIS HB3    H  N N 263 
HIS HD1    H  N N 264 
HIS HD2    H  N N 265 
HIS HE1    H  N N 266 
HIS HE2    H  N N 267 
HIS HXT    H  N N 268 
ILE N      N  N N 269 
ILE CA     C  N S 270 
ILE C      C  N N 271 
ILE O      O  N N 272 
ILE CB     C  N S 273 
ILE CG1    C  N N 274 
ILE CG2    C  N N 275 
ILE CD1    C  N N 276 
ILE OXT    O  N N 277 
ILE H      H  N N 278 
ILE H2     H  N N 279 
ILE HA     H  N N 280 
ILE HB     H  N N 281 
ILE HG12   H  N N 282 
ILE HG13   H  N N 283 
ILE HG21   H  N N 284 
ILE HG22   H  N N 285 
ILE HG23   H  N N 286 
ILE HD11   H  N N 287 
ILE HD12   H  N N 288 
ILE HD13   H  N N 289 
ILE HXT    H  N N 290 
LEU N      N  N N 291 
LEU CA     C  N S 292 
LEU C      C  N N 293 
LEU O      O  N N 294 
LEU CB     C  N N 295 
LEU CG     C  N N 296 
LEU CD1    C  N N 297 
LEU CD2    C  N N 298 
LEU OXT    O  N N 299 
LEU H      H  N N 300 
LEU H2     H  N N 301 
LEU HA     H  N N 302 
LEU HB2    H  N N 303 
LEU HB3    H  N N 304 
LEU HG     H  N N 305 
LEU HD11   H  N N 306 
LEU HD12   H  N N 307 
LEU HD13   H  N N 308 
LEU HD21   H  N N 309 
LEU HD22   H  N N 310 
LEU HD23   H  N N 311 
LEU HXT    H  N N 312 
LYS N      N  N N 313 
LYS CA     C  N S 314 
LYS C      C  N N 315 
LYS O      O  N N 316 
LYS CB     C  N N 317 
LYS CG     C  N N 318 
LYS CD     C  N N 319 
LYS CE     C  N N 320 
LYS NZ     N  N N 321 
LYS OXT    O  N N 322 
LYS H      H  N N 323 
LYS H2     H  N N 324 
LYS HA     H  N N 325 
LYS HB2    H  N N 326 
LYS HB3    H  N N 327 
LYS HG2    H  N N 328 
LYS HG3    H  N N 329 
LYS HD2    H  N N 330 
LYS HD3    H  N N 331 
LYS HE2    H  N N 332 
LYS HE3    H  N N 333 
LYS HZ1    H  N N 334 
LYS HZ2    H  N N 335 
LYS HZ3    H  N N 336 
LYS HXT    H  N N 337 
MET N      N  N N 338 
MET CA     C  N S 339 
MET C      C  N N 340 
MET O      O  N N 341 
MET CB     C  N N 342 
MET CG     C  N N 343 
MET SD     S  N N 344 
MET CE     C  N N 345 
MET OXT    O  N N 346 
MET H      H  N N 347 
MET H2     H  N N 348 
MET HA     H  N N 349 
MET HB2    H  N N 350 
MET HB3    H  N N 351 
MET HG2    H  N N 352 
MET HG3    H  N N 353 
MET HE1    H  N N 354 
MET HE2    H  N N 355 
MET HE3    H  N N 356 
MET HXT    H  N N 357 
PHE N      N  N N 358 
PHE CA     C  N S 359 
PHE C      C  N N 360 
PHE O      O  N N 361 
PHE CB     C  N N 362 
PHE CG     C  Y N 363 
PHE CD1    C  Y N 364 
PHE CD2    C  Y N 365 
PHE CE1    C  Y N 366 
PHE CE2    C  Y N 367 
PHE CZ     C  Y N 368 
PHE OXT    O  N N 369 
PHE H      H  N N 370 
PHE H2     H  N N 371 
PHE HA     H  N N 372 
PHE HB2    H  N N 373 
PHE HB3    H  N N 374 
PHE HD1    H  N N 375 
PHE HD2    H  N N 376 
PHE HE1    H  N N 377 
PHE HE2    H  N N 378 
PHE HZ     H  N N 379 
PHE HXT    H  N N 380 
PRO N      N  N N 381 
PRO CA     C  N S 382 
PRO C      C  N N 383 
PRO O      O  N N 384 
PRO CB     C  N N 385 
PRO CG     C  N N 386 
PRO CD     C  N N 387 
PRO OXT    O  N N 388 
PRO H      H  N N 389 
PRO HA     H  N N 390 
PRO HB2    H  N N 391 
PRO HB3    H  N N 392 
PRO HG2    H  N N 393 
PRO HG3    H  N N 394 
PRO HD2    H  N N 395 
PRO HD3    H  N N 396 
PRO HXT    H  N N 397 
SER N      N  N N 398 
SER CA     C  N S 399 
SER C      C  N N 400 
SER O      O  N N 401 
SER CB     C  N N 402 
SER OG     O  N N 403 
SER OXT    O  N N 404 
SER H      H  N N 405 
SER H2     H  N N 406 
SER HA     H  N N 407 
SER HB2    H  N N 408 
SER HB3    H  N N 409 
SER HG     H  N N 410 
SER HXT    H  N N 411 
THR N      N  N N 412 
THR CA     C  N S 413 
THR C      C  N N 414 
THR O      O  N N 415 
THR CB     C  N R 416 
THR OG1    O  N N 417 
THR CG2    C  N N 418 
THR OXT    O  N N 419 
THR H      H  N N 420 
THR H2     H  N N 421 
THR HA     H  N N 422 
THR HB     H  N N 423 
THR HG1    H  N N 424 
THR HG21   H  N N 425 
THR HG22   H  N N 426 
THR HG23   H  N N 427 
THR HXT    H  N N 428 
TYR N      N  N N 429 
TYR CA     C  N S 430 
TYR C      C  N N 431 
TYR O      O  N N 432 
TYR CB     C  N N 433 
TYR CG     C  Y N 434 
TYR CD1    C  Y N 435 
TYR CD2    C  Y N 436 
TYR CE1    C  Y N 437 
TYR CE2    C  Y N 438 
TYR CZ     C  Y N 439 
TYR OH     O  N N 440 
TYR OXT    O  N N 441 
TYR H      H  N N 442 
TYR H2     H  N N 443 
TYR HA     H  N N 444 
TYR HB2    H  N N 445 
TYR HB3    H  N N 446 
TYR HD1    H  N N 447 
TYR HD2    H  N N 448 
TYR HE1    H  N N 449 
TYR HE2    H  N N 450 
TYR HH     H  N N 451 
TYR HXT    H  N N 452 
U   OP3    O  N N 453 
U   P      P  N N 454 
U   OP1    O  N N 455 
U   OP2    O  N N 456 
U   "O5'"  O  N N 457 
U   "C5'"  C  N N 458 
U   "C4'"  C  N R 459 
U   "O4'"  O  N N 460 
U   "C3'"  C  N S 461 
U   "O3'"  O  N N 462 
U   "C2'"  C  N R 463 
U   "O2'"  O  N N 464 
U   "C1'"  C  N R 465 
U   N1     N  N N 466 
U   C2     C  N N 467 
U   O2     O  N N 468 
U   N3     N  N N 469 
U   C4     C  N N 470 
U   O4     O  N N 471 
U   C5     C  N N 472 
U   C6     C  N N 473 
U   HOP3   H  N N 474 
U   HOP2   H  N N 475 
U   "H5'"  H  N N 476 
U   "H5''" H  N N 477 
U   "H4'"  H  N N 478 
U   "H3'"  H  N N 479 
U   "HO3'" H  N N 480 
U   "H2'"  H  N N 481 
U   "HO2'" H  N N 482 
U   "H1'"  H  N N 483 
U   H3     H  N N 484 
U   H5     H  N N 485 
U   H6     H  N N 486 
VAL N      N  N N 487 
VAL CA     C  N S 488 
VAL C      C  N N 489 
VAL O      O  N N 490 
VAL CB     C  N N 491 
VAL CG1    C  N N 492 
VAL CG2    C  N N 493 
VAL OXT    O  N N 494 
VAL H      H  N N 495 
VAL H2     H  N N 496 
VAL HA     H  N N 497 
VAL HB     H  N N 498 
VAL HG11   H  N N 499 
VAL HG12   H  N N 500 
VAL HG13   H  N N 501 
VAL HG21   H  N N 502 
VAL HG22   H  N N 503 
VAL HG23   H  N N 504 
VAL HXT    H  N N 505 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A   OP3   P      sing N N 1   
A   OP3   HOP3   sing N N 2   
A   P     OP1    doub N N 3   
A   P     OP2    sing N N 4   
A   P     "O5'"  sing N N 5   
A   OP2   HOP2   sing N N 6   
A   "O5'" "C5'"  sing N N 7   
A   "C5'" "C4'"  sing N N 8   
A   "C5'" "H5'"  sing N N 9   
A   "C5'" "H5''" sing N N 10  
A   "C4'" "O4'"  sing N N 11  
A   "C4'" "C3'"  sing N N 12  
A   "C4'" "H4'"  sing N N 13  
A   "O4'" "C1'"  sing N N 14  
A   "C3'" "O3'"  sing N N 15  
A   "C3'" "C2'"  sing N N 16  
A   "C3'" "H3'"  sing N N 17  
A   "O3'" "HO3'" sing N N 18  
A   "C2'" "O2'"  sing N N 19  
A   "C2'" "C1'"  sing N N 20  
A   "C2'" "H2'"  sing N N 21  
A   "O2'" "HO2'" sing N N 22  
A   "C1'" N9     sing N N 23  
A   "C1'" "H1'"  sing N N 24  
A   N9    C8     sing Y N 25  
A   N9    C4     sing Y N 26  
A   C8    N7     doub Y N 27  
A   C8    H8     sing N N 28  
A   N7    C5     sing Y N 29  
A   C5    C6     sing Y N 30  
A   C5    C4     doub Y N 31  
A   C6    N6     sing N N 32  
A   C6    N1     doub Y N 33  
A   N6    H61    sing N N 34  
A   N6    H62    sing N N 35  
A   N1    C2     sing Y N 36  
A   C2    N3     doub Y N 37  
A   C2    H2     sing N N 38  
A   N3    C4     sing Y N 39  
ALA N     CA     sing N N 40  
ALA N     H      sing N N 41  
ALA N     H2     sing N N 42  
ALA CA    C      sing N N 43  
ALA CA    CB     sing N N 44  
ALA CA    HA     sing N N 45  
ALA C     O      doub N N 46  
ALA C     OXT    sing N N 47  
ALA CB    HB1    sing N N 48  
ALA CB    HB2    sing N N 49  
ALA CB    HB3    sing N N 50  
ALA OXT   HXT    sing N N 51  
ARG N     CA     sing N N 52  
ARG N     H      sing N N 53  
ARG N     H2     sing N N 54  
ARG CA    C      sing N N 55  
ARG CA    CB     sing N N 56  
ARG CA    HA     sing N N 57  
ARG C     O      doub N N 58  
ARG C     OXT    sing N N 59  
ARG CB    CG     sing N N 60  
ARG CB    HB2    sing N N 61  
ARG CB    HB3    sing N N 62  
ARG CG    CD     sing N N 63  
ARG CG    HG2    sing N N 64  
ARG CG    HG3    sing N N 65  
ARG CD    NE     sing N N 66  
ARG CD    HD2    sing N N 67  
ARG CD    HD3    sing N N 68  
ARG NE    CZ     sing N N 69  
ARG NE    HE     sing N N 70  
ARG CZ    NH1    sing N N 71  
ARG CZ    NH2    doub N N 72  
ARG NH1   HH11   sing N N 73  
ARG NH1   HH12   sing N N 74  
ARG NH2   HH21   sing N N 75  
ARG NH2   HH22   sing N N 76  
ARG OXT   HXT    sing N N 77  
ASN N     CA     sing N N 78  
ASN N     H      sing N N 79  
ASN N     H2     sing N N 80  
ASN CA    C      sing N N 81  
ASN CA    CB     sing N N 82  
ASN CA    HA     sing N N 83  
ASN C     O      doub N N 84  
ASN C     OXT    sing N N 85  
ASN CB    CG     sing N N 86  
ASN CB    HB2    sing N N 87  
ASN CB    HB3    sing N N 88  
ASN CG    OD1    doub N N 89  
ASN CG    ND2    sing N N 90  
ASN ND2   HD21   sing N N 91  
ASN ND2   HD22   sing N N 92  
ASN OXT   HXT    sing N N 93  
ASP N     CA     sing N N 94  
ASP N     H      sing N N 95  
ASP N     H2     sing N N 96  
ASP CA    C      sing N N 97  
ASP CA    CB     sing N N 98  
ASP CA    HA     sing N N 99  
ASP C     O      doub N N 100 
ASP C     OXT    sing N N 101 
ASP CB    CG     sing N N 102 
ASP CB    HB2    sing N N 103 
ASP CB    HB3    sing N N 104 
ASP CG    OD1    doub N N 105 
ASP CG    OD2    sing N N 106 
ASP OD2   HD2    sing N N 107 
ASP OXT   HXT    sing N N 108 
C   OP3   P      sing N N 109 
C   OP3   HOP3   sing N N 110 
C   P     OP1    doub N N 111 
C   P     OP2    sing N N 112 
C   P     "O5'"  sing N N 113 
C   OP2   HOP2   sing N N 114 
C   "O5'" "C5'"  sing N N 115 
C   "C5'" "C4'"  sing N N 116 
C   "C5'" "H5'"  sing N N 117 
C   "C5'" "H5''" sing N N 118 
C   "C4'" "O4'"  sing N N 119 
C   "C4'" "C3'"  sing N N 120 
C   "C4'" "H4'"  sing N N 121 
C   "O4'" "C1'"  sing N N 122 
C   "C3'" "O3'"  sing N N 123 
C   "C3'" "C2'"  sing N N 124 
C   "C3'" "H3'"  sing N N 125 
C   "O3'" "HO3'" sing N N 126 
C   "C2'" "O2'"  sing N N 127 
C   "C2'" "C1'"  sing N N 128 
C   "C2'" "H2'"  sing N N 129 
C   "O2'" "HO2'" sing N N 130 
C   "C1'" N1     sing N N 131 
C   "C1'" "H1'"  sing N N 132 
C   N1    C2     sing N N 133 
C   N1    C6     sing N N 134 
C   C2    O2     doub N N 135 
C   C2    N3     sing N N 136 
C   N3    C4     doub N N 137 
C   C4    N4     sing N N 138 
C   C4    C5     sing N N 139 
C   N4    H41    sing N N 140 
C   N4    H42    sing N N 141 
C   C5    C6     doub N N 142 
C   C5    H5     sing N N 143 
C   C6    H6     sing N N 144 
CYS N     CA     sing N N 145 
CYS N     H      sing N N 146 
CYS N     H2     sing N N 147 
CYS CA    C      sing N N 148 
CYS CA    CB     sing N N 149 
CYS CA    HA     sing N N 150 
CYS C     O      doub N N 151 
CYS C     OXT    sing N N 152 
CYS CB    SG     sing N N 153 
CYS CB    HB2    sing N N 154 
CYS CB    HB3    sing N N 155 
CYS SG    HG     sing N N 156 
CYS OXT   HXT    sing N N 157 
G   OP3   P      sing N N 158 
G   OP3   HOP3   sing N N 159 
G   P     OP1    doub N N 160 
G   P     OP2    sing N N 161 
G   P     "O5'"  sing N N 162 
G   OP2   HOP2   sing N N 163 
G   "O5'" "C5'"  sing N N 164 
G   "C5'" "C4'"  sing N N 165 
G   "C5'" "H5'"  sing N N 166 
G   "C5'" "H5''" sing N N 167 
G   "C4'" "O4'"  sing N N 168 
G   "C4'" "C3'"  sing N N 169 
G   "C4'" "H4'"  sing N N 170 
G   "O4'" "C1'"  sing N N 171 
G   "C3'" "O3'"  sing N N 172 
G   "C3'" "C2'"  sing N N 173 
G   "C3'" "H3'"  sing N N 174 
G   "O3'" "HO3'" sing N N 175 
G   "C2'" "O2'"  sing N N 176 
G   "C2'" "C1'"  sing N N 177 
G   "C2'" "H2'"  sing N N 178 
G   "O2'" "HO2'" sing N N 179 
G   "C1'" N9     sing N N 180 
G   "C1'" "H1'"  sing N N 181 
G   N9    C8     sing Y N 182 
G   N9    C4     sing Y N 183 
G   C8    N7     doub Y N 184 
G   C8    H8     sing N N 185 
G   N7    C5     sing Y N 186 
G   C5    C6     sing N N 187 
G   C5    C4     doub Y N 188 
G   C6    O6     doub N N 189 
G   C6    N1     sing N N 190 
G   N1    C2     sing N N 191 
G   N1    H1     sing N N 192 
G   C2    N2     sing N N 193 
G   C2    N3     doub N N 194 
G   N2    H21    sing N N 195 
G   N2    H22    sing N N 196 
G   N3    C4     sing N N 197 
GLN N     CA     sing N N 198 
GLN N     H      sing N N 199 
GLN N     H2     sing N N 200 
GLN CA    C      sing N N 201 
GLN CA    CB     sing N N 202 
GLN CA    HA     sing N N 203 
GLN C     O      doub N N 204 
GLN C     OXT    sing N N 205 
GLN CB    CG     sing N N 206 
GLN CB    HB2    sing N N 207 
GLN CB    HB3    sing N N 208 
GLN CG    CD     sing N N 209 
GLN CG    HG2    sing N N 210 
GLN CG    HG3    sing N N 211 
GLN CD    OE1    doub N N 212 
GLN CD    NE2    sing N N 213 
GLN NE2   HE21   sing N N 214 
GLN NE2   HE22   sing N N 215 
GLN OXT   HXT    sing N N 216 
GLU N     CA     sing N N 217 
GLU N     H      sing N N 218 
GLU N     H2     sing N N 219 
GLU CA    C      sing N N 220 
GLU CA    CB     sing N N 221 
GLU CA    HA     sing N N 222 
GLU C     O      doub N N 223 
GLU C     OXT    sing N N 224 
GLU CB    CG     sing N N 225 
GLU CB    HB2    sing N N 226 
GLU CB    HB3    sing N N 227 
GLU CG    CD     sing N N 228 
GLU CG    HG2    sing N N 229 
GLU CG    HG3    sing N N 230 
GLU CD    OE1    doub N N 231 
GLU CD    OE2    sing N N 232 
GLU OE2   HE2    sing N N 233 
GLU OXT   HXT    sing N N 234 
GLY N     CA     sing N N 235 
GLY N     H      sing N N 236 
GLY N     H2     sing N N 237 
GLY CA    C      sing N N 238 
GLY CA    HA2    sing N N 239 
GLY CA    HA3    sing N N 240 
GLY C     O      doub N N 241 
GLY C     OXT    sing N N 242 
GLY OXT   HXT    sing N N 243 
HIS N     CA     sing N N 244 
HIS N     H      sing N N 245 
HIS N     H2     sing N N 246 
HIS CA    C      sing N N 247 
HIS CA    CB     sing N N 248 
HIS CA    HA     sing N N 249 
HIS C     O      doub N N 250 
HIS C     OXT    sing N N 251 
HIS CB    CG     sing N N 252 
HIS CB    HB2    sing N N 253 
HIS CB    HB3    sing N N 254 
HIS CG    ND1    sing Y N 255 
HIS CG    CD2    doub Y N 256 
HIS ND1   CE1    doub Y N 257 
HIS ND1   HD1    sing N N 258 
HIS CD2   NE2    sing Y N 259 
HIS CD2   HD2    sing N N 260 
HIS CE1   NE2    sing Y N 261 
HIS CE1   HE1    sing N N 262 
HIS NE2   HE2    sing N N 263 
HIS OXT   HXT    sing N N 264 
ILE N     CA     sing N N 265 
ILE N     H      sing N N 266 
ILE N     H2     sing N N 267 
ILE CA    C      sing N N 268 
ILE CA    CB     sing N N 269 
ILE CA    HA     sing N N 270 
ILE C     O      doub N N 271 
ILE C     OXT    sing N N 272 
ILE CB    CG1    sing N N 273 
ILE CB    CG2    sing N N 274 
ILE CB    HB     sing N N 275 
ILE CG1   CD1    sing N N 276 
ILE CG1   HG12   sing N N 277 
ILE CG1   HG13   sing N N 278 
ILE CG2   HG21   sing N N 279 
ILE CG2   HG22   sing N N 280 
ILE CG2   HG23   sing N N 281 
ILE CD1   HD11   sing N N 282 
ILE CD1   HD12   sing N N 283 
ILE CD1   HD13   sing N N 284 
ILE OXT   HXT    sing N N 285 
LEU N     CA     sing N N 286 
LEU N     H      sing N N 287 
LEU N     H2     sing N N 288 
LEU CA    C      sing N N 289 
LEU CA    CB     sing N N 290 
LEU CA    HA     sing N N 291 
LEU C     O      doub N N 292 
LEU C     OXT    sing N N 293 
LEU CB    CG     sing N N 294 
LEU CB    HB2    sing N N 295 
LEU CB    HB3    sing N N 296 
LEU CG    CD1    sing N N 297 
LEU CG    CD2    sing N N 298 
LEU CG    HG     sing N N 299 
LEU CD1   HD11   sing N N 300 
LEU CD1   HD12   sing N N 301 
LEU CD1   HD13   sing N N 302 
LEU CD2   HD21   sing N N 303 
LEU CD2   HD22   sing N N 304 
LEU CD2   HD23   sing N N 305 
LEU OXT   HXT    sing N N 306 
LYS N     CA     sing N N 307 
LYS N     H      sing N N 308 
LYS N     H2     sing N N 309 
LYS CA    C      sing N N 310 
LYS CA    CB     sing N N 311 
LYS CA    HA     sing N N 312 
LYS C     O      doub N N 313 
LYS C     OXT    sing N N 314 
LYS CB    CG     sing N N 315 
LYS CB    HB2    sing N N 316 
LYS CB    HB3    sing N N 317 
LYS CG    CD     sing N N 318 
LYS CG    HG2    sing N N 319 
LYS CG    HG3    sing N N 320 
LYS CD    CE     sing N N 321 
LYS CD    HD2    sing N N 322 
LYS CD    HD3    sing N N 323 
LYS CE    NZ     sing N N 324 
LYS CE    HE2    sing N N 325 
LYS CE    HE3    sing N N 326 
LYS NZ    HZ1    sing N N 327 
LYS NZ    HZ2    sing N N 328 
LYS NZ    HZ3    sing N N 329 
LYS OXT   HXT    sing N N 330 
MET N     CA     sing N N 331 
MET N     H      sing N N 332 
MET N     H2     sing N N 333 
MET CA    C      sing N N 334 
MET CA    CB     sing N N 335 
MET CA    HA     sing N N 336 
MET C     O      doub N N 337 
MET C     OXT    sing N N 338 
MET CB    CG     sing N N 339 
MET CB    HB2    sing N N 340 
MET CB    HB3    sing N N 341 
MET CG    SD     sing N N 342 
MET CG    HG2    sing N N 343 
MET CG    HG3    sing N N 344 
MET SD    CE     sing N N 345 
MET CE    HE1    sing N N 346 
MET CE    HE2    sing N N 347 
MET CE    HE3    sing N N 348 
MET OXT   HXT    sing N N 349 
PHE N     CA     sing N N 350 
PHE N     H      sing N N 351 
PHE N     H2     sing N N 352 
PHE CA    C      sing N N 353 
PHE CA    CB     sing N N 354 
PHE CA    HA     sing N N 355 
PHE C     O      doub N N 356 
PHE C     OXT    sing N N 357 
PHE CB    CG     sing N N 358 
PHE CB    HB2    sing N N 359 
PHE CB    HB3    sing N N 360 
PHE CG    CD1    doub Y N 361 
PHE CG    CD2    sing Y N 362 
PHE CD1   CE1    sing Y N 363 
PHE CD1   HD1    sing N N 364 
PHE CD2   CE2    doub Y N 365 
PHE CD2   HD2    sing N N 366 
PHE CE1   CZ     doub Y N 367 
PHE CE1   HE1    sing N N 368 
PHE CE2   CZ     sing Y N 369 
PHE CE2   HE2    sing N N 370 
PHE CZ    HZ     sing N N 371 
PHE OXT   HXT    sing N N 372 
PRO N     CA     sing N N 373 
PRO N     CD     sing N N 374 
PRO N     H      sing N N 375 
PRO CA    C      sing N N 376 
PRO CA    CB     sing N N 377 
PRO CA    HA     sing N N 378 
PRO C     O      doub N N 379 
PRO C     OXT    sing N N 380 
PRO CB    CG     sing N N 381 
PRO CB    HB2    sing N N 382 
PRO CB    HB3    sing N N 383 
PRO CG    CD     sing N N 384 
PRO CG    HG2    sing N N 385 
PRO CG    HG3    sing N N 386 
PRO CD    HD2    sing N N 387 
PRO CD    HD3    sing N N 388 
PRO OXT   HXT    sing N N 389 
SER N     CA     sing N N 390 
SER N     H      sing N N 391 
SER N     H2     sing N N 392 
SER CA    C      sing N N 393 
SER CA    CB     sing N N 394 
SER CA    HA     sing N N 395 
SER C     O      doub N N 396 
SER C     OXT    sing N N 397 
SER CB    OG     sing N N 398 
SER CB    HB2    sing N N 399 
SER CB    HB3    sing N N 400 
SER OG    HG     sing N N 401 
SER OXT   HXT    sing N N 402 
THR N     CA     sing N N 403 
THR N     H      sing N N 404 
THR N     H2     sing N N 405 
THR CA    C      sing N N 406 
THR CA    CB     sing N N 407 
THR CA    HA     sing N N 408 
THR C     O      doub N N 409 
THR C     OXT    sing N N 410 
THR CB    OG1    sing N N 411 
THR CB    CG2    sing N N 412 
THR CB    HB     sing N N 413 
THR OG1   HG1    sing N N 414 
THR CG2   HG21   sing N N 415 
THR CG2   HG22   sing N N 416 
THR CG2   HG23   sing N N 417 
THR OXT   HXT    sing N N 418 
TYR N     CA     sing N N 419 
TYR N     H      sing N N 420 
TYR N     H2     sing N N 421 
TYR CA    C      sing N N 422 
TYR CA    CB     sing N N 423 
TYR CA    HA     sing N N 424 
TYR C     O      doub N N 425 
TYR C     OXT    sing N N 426 
TYR CB    CG     sing N N 427 
TYR CB    HB2    sing N N 428 
TYR CB    HB3    sing N N 429 
TYR CG    CD1    doub Y N 430 
TYR CG    CD2    sing Y N 431 
TYR CD1   CE1    sing Y N 432 
TYR CD1   HD1    sing N N 433 
TYR CD2   CE2    doub Y N 434 
TYR CD2   HD2    sing N N 435 
TYR CE1   CZ     doub Y N 436 
TYR CE1   HE1    sing N N 437 
TYR CE2   CZ     sing Y N 438 
TYR CE2   HE2    sing N N 439 
TYR CZ    OH     sing N N 440 
TYR OH    HH     sing N N 441 
TYR OXT   HXT    sing N N 442 
U   OP3   P      sing N N 443 
U   OP3   HOP3   sing N N 444 
U   P     OP1    doub N N 445 
U   P     OP2    sing N N 446 
U   P     "O5'"  sing N N 447 
U   OP2   HOP2   sing N N 448 
U   "O5'" "C5'"  sing N N 449 
U   "C5'" "C4'"  sing N N 450 
U   "C5'" "H5'"  sing N N 451 
U   "C5'" "H5''" sing N N 452 
U   "C4'" "O4'"  sing N N 453 
U   "C4'" "C3'"  sing N N 454 
U   "C4'" "H4'"  sing N N 455 
U   "O4'" "C1'"  sing N N 456 
U   "C3'" "O3'"  sing N N 457 
U   "C3'" "C2'"  sing N N 458 
U   "C3'" "H3'"  sing N N 459 
U   "O3'" "HO3'" sing N N 460 
U   "C2'" "O2'"  sing N N 461 
U   "C2'" "C1'"  sing N N 462 
U   "C2'" "H2'"  sing N N 463 
U   "O2'" "HO2'" sing N N 464 
U   "C1'" N1     sing N N 465 
U   "C1'" "H1'"  sing N N 466 
U   N1    C2     sing N N 467 
U   N1    C6     sing N N 468 
U   C2    O2     doub N N 469 
U   C2    N3     sing N N 470 
U   N3    C4     sing N N 471 
U   N3    H3     sing N N 472 
U   C4    O4     doub N N 473 
U   C4    C5     sing N N 474 
U   C5    C6     doub N N 475 
U   C5    H5     sing N N 476 
U   C6    H6     sing N N 477 
VAL N     CA     sing N N 478 
VAL N     H      sing N N 479 
VAL N     H2     sing N N 480 
VAL CA    C      sing N N 481 
VAL CA    CB     sing N N 482 
VAL CA    HA     sing N N 483 
VAL C     O      doub N N 484 
VAL C     OXT    sing N N 485 
VAL CB    CG1    sing N N 486 
VAL CB    CG2    sing N N 487 
VAL CB    HB     sing N N 488 
VAL CG1   HG11   sing N N 489 
VAL CG1   HG12   sing N N 490 
VAL CG1   HG13   sing N N 491 
VAL CG2   HG21   sing N N 492 
VAL CG2   HG22   sing N N 493 
VAL CG2   HG23   sing N N 494 
VAL OXT   HXT    sing N N 495 
# 
loop_
_ndb_struct_conf_na.entry_id 
_ndb_struct_conf_na.feature 
9L6Y 'double helix'        
9L6Y 'a-form double helix' 
# 
loop_
_ndb_struct_na_base_pair.model_number 
_ndb_struct_na_base_pair.i_label_asym_id 
_ndb_struct_na_base_pair.i_label_comp_id 
_ndb_struct_na_base_pair.i_label_seq_id 
_ndb_struct_na_base_pair.i_symmetry 
_ndb_struct_na_base_pair.j_label_asym_id 
_ndb_struct_na_base_pair.j_label_comp_id 
_ndb_struct_na_base_pair.j_label_seq_id 
_ndb_struct_na_base_pair.j_symmetry 
_ndb_struct_na_base_pair.shear 
_ndb_struct_na_base_pair.stretch 
_ndb_struct_na_base_pair.stagger 
_ndb_struct_na_base_pair.buckle 
_ndb_struct_na_base_pair.propeller 
_ndb_struct_na_base_pair.opening 
_ndb_struct_na_base_pair.pair_number 
_ndb_struct_na_base_pair.pair_name 
_ndb_struct_na_base_pair.i_auth_asym_id 
_ndb_struct_na_base_pair.i_auth_seq_id 
_ndb_struct_na_base_pair.i_PDB_ins_code 
_ndb_struct_na_base_pair.j_auth_asym_id 
_ndb_struct_na_base_pair.j_auth_seq_id 
_ndb_struct_na_base_pair.j_PDB_ins_code 
_ndb_struct_na_base_pair.hbond_type_28 
_ndb_struct_na_base_pair.hbond_type_12 
1 B G 1  1_555 B C 33 1_555 -0.189 -0.117 0.397  13.505  3.632  0.272   1  B_G1:C33_B  B 1  ? B 33 ? 19 1 
1 B G 2  1_555 B C 32 1_555 -0.196 -0.138 0.214  4.062   3.017  3.881   2  B_G2:C32_B  B 2  ? B 32 ? 19 1 
1 B A 3  1_555 B U 31 1_555 0.030  -0.133 -0.322 1.080   4.174  2.839   3  B_A3:U31_B  B 3  ? B 31 ? 20 1 
1 B U 4  1_555 B A 30 1_555 0.104  -0.084 -0.231 2.242   1.118  0.025   4  B_U4:A30_B  B 4  ? B 30 ? 20 1 
1 B G 5  1_555 B C 29 1_555 -0.232 -0.130 0.224  0.541   4.832  2.582   5  B_G5:C29_B  B 5  ? B 29 ? 19 1 
1 B C 6  1_555 B G 28 1_555 0.207  -0.129 0.094  -0.027  3.027  -1.842  6  B_C6:G28_B  B 6  ? B 28 ? 19 1 
1 B A 7  1_555 B C 27 1_555 4.255  0.118  -0.004 2.804   2.372  -3.895  7  B_A7:C27_B  B 7  ? B 27 ? ?  ? 
1 B G 8  1_555 B A 26 1_555 7.861  -4.525 0.468  13.635  -7.036 -45.536 8  B_G8:A26_B  B 8  ? B 26 ? ?  ? 
1 B A 9  1_555 B G 25 1_555 -6.403 -4.095 1.231  -12.482 15.565 0.883   9  B_A9:G25_B  B 9  ? B 25 ? 11 9 
1 B G 10 1_555 B C 21 1_555 -0.113 -0.180 -0.467 -6.562  6.181  -0.022  10 B_G10:C21_B B 10 ? B 21 ? 19 1 
1 B A 11 1_555 B U 20 1_555 0.020  -0.119 -0.078 1.659   3.818  3.810   11 B_A11:U20_B B 11 ? B 20 ? 20 1 
1 B A 12 1_555 B U 19 1_555 0.017  -0.143 0.339  -0.136  9.971  0.456   12 B_A12:U19_B B 12 ? B 19 ? 20 1 
1 B C 13 1_555 B G 18 1_555 0.180  -0.136 0.226  7.070   12.378 2.510   13 B_C13:G18_B B 13 ? B 18 ? 19 1 
1 D G 2  1_555 D C 32 1_555 -0.193 -0.162 -0.781 -6.287  -6.818 2.830   14 D_G2:C32_D  D 2  ? D 32 ? 19 1 
1 D A 3  1_555 D U 31 1_555 0.561  0.633  -0.267 -12.629 -7.684 40.283  15 D_A3:U31_D  D 3  ? D 31 ? ?  1 
1 D U 4  1_555 D A 30 1_555 -0.123 -0.010 -0.030 2.358   -4.726 -4.675  16 D_U4:A30_D  D 4  ? D 30 ? 20 1 
1 D G 5  1_555 D C 29 1_555 -0.216 -0.045 -0.107 -7.208  -6.122 1.703   17 D_G5:C29_D  D 5  ? D 29 ? 19 1 
1 D C 6  1_555 D G 28 1_555 0.097  -0.167 0.216  -5.744  -2.928 -5.142  18 D_C6:G28_D  D 6  ? D 28 ? 19 1 
1 D A 7  1_555 D C 27 1_555 4.084  0.101  -0.091 -7.077  0.423  -7.563  19 D_A7:C27_D  D 7  ? D 27 ? ?  ? 
1 D G 8  1_555 D A 26 1_555 7.624  -4.703 0.401  12.078  -4.427 -41.462 20 D_G8:A26_D  D 8  ? D 26 ? ?  ? 
1 D A 9  1_555 D G 25 1_555 -6.270 -4.068 1.182  -11.841 16.925 -1.723  21 D_A9:G25_D  D 9  ? D 25 ? 11 9 
1 D G 10 1_555 D C 21 1_555 -0.141 -0.166 -0.470 -7.366  4.172  1.617   22 D_G10:C21_D D 10 ? D 21 ? 19 1 
1 D A 11 1_555 D U 20 1_555 -0.001 -0.134 -0.412 -7.459  2.005  2.773   23 D_A11:U20_D D 11 ? D 20 ? 20 1 
1 D A 12 1_555 D U 19 1_555 0.065  -0.082 -0.144 -2.948  6.945  2.797   24 D_A12:U19_D D 12 ? D 19 ? 20 1 
1 D C 13 1_555 D G 18 1_555 0.260  -0.179 0.297  2.884   13.838 1.739   25 D_C13:G18_D D 13 ? D 18 ? 19 1 
# 
loop_
_ndb_struct_na_base_pair_step.model_number 
_ndb_struct_na_base_pair_step.i_label_asym_id_1 
_ndb_struct_na_base_pair_step.i_label_comp_id_1 
_ndb_struct_na_base_pair_step.i_label_seq_id_1 
_ndb_struct_na_base_pair_step.i_symmetry_1 
_ndb_struct_na_base_pair_step.j_label_asym_id_1 
_ndb_struct_na_base_pair_step.j_label_comp_id_1 
_ndb_struct_na_base_pair_step.j_label_seq_id_1 
_ndb_struct_na_base_pair_step.j_symmetry_1 
_ndb_struct_na_base_pair_step.i_label_asym_id_2 
_ndb_struct_na_base_pair_step.i_label_comp_id_2 
_ndb_struct_na_base_pair_step.i_label_seq_id_2 
_ndb_struct_na_base_pair_step.i_symmetry_2 
_ndb_struct_na_base_pair_step.j_label_asym_id_2 
_ndb_struct_na_base_pair_step.j_label_comp_id_2 
_ndb_struct_na_base_pair_step.j_label_seq_id_2 
_ndb_struct_na_base_pair_step.j_symmetry_2 
_ndb_struct_na_base_pair_step.shift 
_ndb_struct_na_base_pair_step.slide 
_ndb_struct_na_base_pair_step.rise 
_ndb_struct_na_base_pair_step.tilt 
_ndb_struct_na_base_pair_step.roll 
_ndb_struct_na_base_pair_step.twist 
_ndb_struct_na_base_pair_step.x_displacement 
_ndb_struct_na_base_pair_step.y_displacement 
_ndb_struct_na_base_pair_step.helical_rise 
_ndb_struct_na_base_pair_step.inclination 
_ndb_struct_na_base_pair_step.tip 
_ndb_struct_na_base_pair_step.helical_twist 
_ndb_struct_na_base_pair_step.step_number 
_ndb_struct_na_base_pair_step.step_name 
_ndb_struct_na_base_pair_step.i_auth_asym_id_1 
_ndb_struct_na_base_pair_step.i_auth_seq_id_1 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.j_auth_asym_id_1 
_ndb_struct_na_base_pair_step.j_auth_seq_id_1 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.i_auth_asym_id_2 
_ndb_struct_na_base_pair_step.i_auth_seq_id_2 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_2 
_ndb_struct_na_base_pair_step.j_auth_asym_id_2 
_ndb_struct_na_base_pair_step.j_auth_seq_id_2 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_2 
1 B G 1  1_555 B C 33 1_555 B G 2  1_555 B C 32 1_555 -0.166 -2.078 3.410 -4.291 5.165   35.781  -4.049 -0.332 3.089 8.316  6.909 
36.385  1  BB_G1G2:C32C33_BB   B 1  ? B 33 ? B 2  ? B 32 ? 
1 B G 2  1_555 B C 32 1_555 B A 3  1_555 B U 31 1_555 -0.690 -1.780 3.336 0.374  2.657   30.786  -3.854 1.367  3.167 4.993  -0.703 
30.900  2  BB_G2A3:U31C32_BB   B 2  ? B 32 ? B 3  ? B 31 ? 
1 B A 3  1_555 B U 31 1_555 B U 4  1_555 B A 30 1_555 0.281  -1.535 3.403 1.345  5.797   34.614  -3.416 -0.264 3.122 9.655  -2.239 
35.107  3  BB_A3U4:A30U31_BB   B 3  ? B 31 ? B 4  ? B 30 ? 
1 B U 4  1_555 B A 30 1_555 B G 5  1_555 B C 29 1_555 0.023  -1.591 3.159 -1.579 11.524  26.525  -5.407 -0.351 2.278 23.718 3.250 
28.921  4  BB_U4G5:C29A30_BB   B 4  ? B 30 ? B 5  ? B 29 ? 
1 B G 5  1_555 B C 29 1_555 B C 6  1_555 B G 28 1_555 -0.265 -1.419 3.239 2.139  9.122   41.317  -2.846 0.573  2.860 12.731 -2.985 
42.321  5  BB_G5C6:G28C29_BB   B 5  ? B 29 ? B 6  ? B 28 ? 
1 B C 6  1_555 B G 28 1_555 B A 7  1_555 B C 27 1_555 -0.673 -1.002 3.418 6.297  5.093   37.214  -2.190 1.840  3.109 7.867  -9.727 
38.054  6  BB_C6A7:C27G28_BB   B 6  ? B 28 ? B 7  ? B 27 ? 
1 B A 7  1_555 B C 27 1_555 B G 8  1_555 B A 26 1_555 -1.478 -1.449 3.408 8.798  4.817   48.758  -2.072 2.394  2.969 5.765  
-10.528 49.717  7  BB_A7G8:A26C27_BB   B 7  ? B 27 ? B 8  ? B 26 ? 
1 B G 8  1_555 B A 26 1_555 B A 9  1_555 B G 25 1_555 2.503  -0.104 3.820 5.305  -21.299 -19.427 5.218  6.207  2.029 47.524 11.837 
-29.233 8  BB_G8A9:G25A26_BB   B 8  ? B 26 ? B 9  ? B 25 ? 
1 B G 10 1_555 B C 21 1_555 B A 11 1_555 B U 20 1_555 0.221  -1.900 3.057 -1.401 6.631   31.898  -4.397 -0.607 2.608 11.898 2.514 
32.591  9  BB_G10A11:U20C21_BB B 10 ? B 21 ? B 11 ? B 20 ? 
1 B A 11 1_555 B U 20 1_555 B A 12 1_555 B U 19 1_555 -0.824 -1.763 3.313 -3.750 10.026  29.958  -4.957 0.856  2.679 18.662 6.979 
31.771  10 BB_A11A12:U19U20_BB B 11 ? B 20 ? B 12 ? B 19 ? 
1 B A 12 1_555 B U 19 1_555 B C 13 1_555 B G 18 1_555 0.268  -1.721 3.192 1.606  6.607   35.423  -3.653 -0.221 2.845 10.736 -2.609 
36.049  11 BB_A12C13:G18U19_BB B 12 ? B 19 ? B 13 ? B 18 ? 
1 D G 2  1_555 D C 32 1_555 D A 3  1_555 D U 31 1_555 1.270  -0.905 3.460 -4.485 3.976   39.327  -1.803 -2.400 3.199 5.867  6.618 
39.763  12 DD_G2A3:U31C32_DD   D 2  ? D 32 ? D 3  ? D 31 ? 
1 D A 3  1_555 D U 31 1_555 D U 4  1_555 D A 30 1_555 -1.628 -0.576 3.063 0.994  7.685   23.586  -3.429 4.059  2.674 18.183 -2.352 
24.810  13 DD_A3U4:A30U31_DD   D 3  ? D 31 ? D 4  ? D 30 ? 
1 D U 4  1_555 D A 30 1_555 D G 5  1_555 D C 29 1_555 -0.099 -1.661 3.121 -3.803 19.796  31.488  -4.758 -0.260 1.801 32.631 6.269 
37.250  14 DD_U4G5:C29A30_DD   D 4  ? D 30 ? D 5  ? D 29 ? 
1 D G 5  1_555 D C 29 1_555 D C 6  1_555 D G 28 1_555 -0.416 -1.534 3.189 -5.131 6.610   35.029  -3.370 -0.016 2.892 10.792 8.378 
35.984  15 DD_G5C6:G28C29_DD   D 5  ? D 29 ? D 6  ? D 28 ? 
1 D C 6  1_555 D G 28 1_555 D A 7  1_555 D C 27 1_555 -0.963 -1.676 3.276 3.871  5.672   41.734  -2.880 1.714  2.937 7.897  -5.390 
42.270  16 DD_C6A7:C27G28_DD   D 6  ? D 28 ? D 7  ? D 27 ? 
1 D A 7  1_555 D C 27 1_555 D G 8  1_555 D A 26 1_555 -1.151 -1.517 3.107 7.842  3.739   47.296  -2.130 1.973  2.774 4.615  -9.679 
48.043  17 DD_A7G8:A26C27_DD   D 7  ? D 27 ? D 8  ? D 26 ? 
1 D G 8  1_555 D A 26 1_555 D A 9  1_555 D G 25 1_555 2.236  -0.101 3.912 3.565  -21.761 -18.830 5.728  5.382  2.214 49.327 8.081 
-28.921 18 DD_G8A9:G25A26_DD   D 8  ? D 26 ? D 9  ? D 25 ? 
1 D G 10 1_555 D C 21 1_555 D A 11 1_555 D U 20 1_555 -0.008 -1.864 3.185 0.662  10.363  32.544  -4.640 0.107  2.491 17.931 -1.145 
34.118  19 DD_G10A11:U20C21_DD D 10 ? D 21 ? D 11 ? D 20 ? 
1 D A 11 1_555 D U 20 1_555 D A 12 1_555 D U 19 1_555 -0.368 -1.547 3.261 -3.158 4.493   28.342  -4.071 0.058  3.007 9.068  6.375 
28.858  20 DD_A11A12:U19U20_DD D 11 ? D 20 ? D 12 ? D 19 ? 
1 D A 12 1_555 D U 19 1_555 D C 13 1_555 D G 18 1_555 0.238  -1.697 3.167 -2.631 7.763   34.157  -3.872 -0.753 2.703 12.986 4.400 
35.099  21 DD_A12C13:G18U19_DD D 12 ? D 19 ? D 13 ? D 18 ? 
# 
_pdbx_audit_support.funding_organization   'Japan Society for the Promotion of Science (JSPS)' 
_pdbx_audit_support.country                Japan 
_pdbx_audit_support.grant_number           19K15701 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   4BW0 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9L6Y 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.017762 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.005224 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.018090 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.012551 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
CA 
N  
O  
P  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N     . TYR A 1 2   ? -0.739  -11.244 27.967  1.00 92.84  ? 2   TYR A N     1 
ATOM   2    C  CA    . TYR A 1 2   ? -1.056  -12.062 29.136  1.00 95.73  ? 2   TYR A CA    1 
ATOM   3    C  C     . TYR A 1 2   ? 0.040   -11.936 30.197  1.00 93.29  ? 2   TYR A C     1 
ATOM   4    O  O     . TYR A 1 2   ? 0.845   -12.853 30.390  1.00 84.93  ? 2   TYR A O     1 
ATOM   5    C  CB    . TYR A 1 2   ? -1.237  -13.530 28.736  1.00 93.71  ? 2   TYR A CB    1 
ATOM   6    C  CG    . TYR A 1 2   ? -2.106  -13.742 27.515  1.00 95.92  ? 2   TYR A CG    1 
ATOM   7    C  CD1   . TYR A 1 2   ? -3.446  -13.356 27.511  1.00 90.13  ? 2   TYR A CD1   1 
ATOM   8    C  CD2   . TYR A 1 2   ? -1.585  -14.323 26.362  1.00 90.68  ? 2   TYR A CD2   1 
ATOM   9    C  CE1   . TYR A 1 2   ? -4.244  -13.548 26.393  1.00 83.41  ? 2   TYR A CE1   1 
ATOM   10   C  CE2   . TYR A 1 2   ? -2.371  -14.519 25.239  1.00 87.60  ? 2   TYR A CE2   1 
ATOM   11   C  CZ    . TYR A 1 2   ? -3.698  -14.129 25.259  1.00 90.58  ? 2   TYR A CZ    1 
ATOM   12   O  OH    . TYR A 1 2   ? -4.477  -14.325 24.140  1.00 86.27  ? 2   TYR A OH    1 
ATOM   13   N  N     . VAL A 1 3   ? 0.078   -10.792 30.873  1.00 95.55  ? 3   VAL A N     1 
ATOM   14   C  CA    . VAL A 1 3   ? 1.058   -10.544 31.923  1.00 86.16  ? 3   VAL A CA    1 
ATOM   15   C  C     . VAL A 1 3   ? 0.539   -11.117 33.236  1.00 87.81  ? 3   VAL A C     1 
ATOM   16   O  O     . VAL A 1 3   ? -0.607  -10.866 33.630  1.00 92.28  ? 3   VAL A O     1 
ATOM   17   C  CB    . VAL A 1 3   ? 1.370   -9.041  32.048  1.00 75.93  ? 3   VAL A CB    1 
ATOM   18   C  CG1   . VAL A 1 3   ? 2.096   -8.557  30.809  1.00 73.39  ? 3   VAL A CG1   1 
ATOM   19   C  CG2   . VAL A 1 3   ? 0.096   -8.234  32.246  1.00 82.64  ? 3   VAL A CG2   1 
ATOM   20   N  N     . ARG A 1 4   ? 1.375   -11.918 33.902  1.00 87.02  ? 4   ARG A N     1 
ATOM   21   C  CA    . ARG A 1 4   ? 1.006   -12.442 35.213  1.00 86.42  ? 4   ARG A CA    1 
ATOM   22   C  C     . ARG A 1 4   ? 1.091   -11.353 36.275  1.00 90.49  ? 4   ARG A C     1 
ATOM   23   O  O     . ARG A 1 4   ? 0.252   -11.290 37.183  1.00 95.82  ? 4   ARG A O     1 
ATOM   24   C  CB    . ARG A 1 4   ? 1.904   -13.626 35.576  1.00 81.63  ? 4   ARG A CB    1 
ATOM   25   C  CG    . ARG A 1 4   ? 1.420   -14.442 36.766  1.00 88.21  ? 4   ARG A CG    1 
ATOM   26   C  CD    . ARG A 1 4   ? 0.432   -15.515 36.337  1.00 93.69  ? 4   ARG A CD    1 
ATOM   27   N  NE    . ARG A 1 4   ? 0.217   -16.510 37.382  1.00 96.65  ? 4   ARG A NE    1 
ATOM   28   C  CZ    . ARG A 1 4   ? -0.814  -16.513 38.217  1.00 97.08  ? 4   ARG A CZ    1 
ATOM   29   N  NH1   . ARG A 1 4   ? -1.761  -15.588 38.149  1.00 91.70  ? 4   ARG A NH1   1 
ATOM   30   N  NH2   . ARG A 1 4   ? -0.897  -17.466 39.143  1.00 87.35  ? 4   ARG A NH2   1 
ATOM   31   N  N     . PHE A 1 5   ? 2.100   -10.488 36.173  1.00 84.97  ? 5   PHE A N     1 
ATOM   32   C  CA    . PHE A 1 5   ? 2.258   -9.332  37.042  1.00 85.39  ? 5   PHE A CA    1 
ATOM   33   C  C     . PHE A 1 5   ? 2.796   -8.184  36.200  1.00 81.90  ? 5   PHE A C     1 
ATOM   34   O  O     . PHE A 1 5   ? 3.082   -8.343  35.009  1.00 83.65  ? 5   PHE A O     1 
ATOM   35   C  CB    . PHE A 1 5   ? 3.172   -9.646  38.232  1.00 81.95  ? 5   PHE A CB    1 
ATOM   36   C  CG    . PHE A 1 5   ? 4.439   -10.355 37.856  1.00 82.08  ? 5   PHE A CG    1 
ATOM   37   C  CD1   . PHE A 1 5   ? 5.477   -9.680  37.232  1.00 84.28  ? 5   PHE A CD1   1 
ATOM   38   C  CD2   . PHE A 1 5   ? 4.585   -11.706 38.111  1.00 81.35  ? 5   PHE A CD2   1 
ATOM   39   C  CE1   . PHE A 1 5   ? 6.643   -10.340 36.886  1.00 80.06  ? 5   PHE A CE1   1 
ATOM   40   C  CE2   . PHE A 1 5   ? 5.747   -12.372 37.765  1.00 79.28  ? 5   PHE A CE2   1 
ATOM   41   C  CZ    . PHE A 1 5   ? 6.777   -11.689 37.151  1.00 73.37  ? 5   PHE A CZ    1 
ATOM   42   N  N     . GLU A 1 6   ? 2.923   -7.014  36.820  1.00 74.94  ? 6   GLU A N     1 
ATOM   43   C  CA    . GLU A 1 6   ? 3.410   -5.818  36.142  1.00 75.75  ? 6   GLU A CA    1 
ATOM   44   C  C     . GLU A 1 6   ? 4.684   -5.357  36.840  1.00 80.55  ? 6   GLU A C     1 
ATOM   45   O  O     . GLU A 1 6   ? 4.653   -4.973  38.013  1.00 83.55  ? 6   GLU A O     1 
ATOM   46   C  CB    . GLU A 1 6   ? 2.347   -4.720  36.130  1.00 70.37  ? 6   GLU A CB    1 
ATOM   47   N  N     . VAL A 1 7   ? 5.798   -5.404  36.126  1.00 78.86  ? 7   VAL A N     1 
ATOM   48   C  CA    . VAL A 1 7   ? 7.078   -4.980  36.698  1.00 72.48  ? 7   VAL A CA    1 
ATOM   49   C  C     . VAL A 1 7   ? 7.208   -3.470  36.542  1.00 69.04  ? 7   VAL A C     1 
ATOM   50   O  O     . VAL A 1 7   ? 6.908   -2.938  35.460  1.00 66.56  ? 7   VAL A O     1 
ATOM   51   C  CB    . VAL A 1 7   ? 8.233   -5.713  36.020  1.00 65.88  ? 7   VAL A CB    1 
ATOM   52   C  CG1   . VAL A 1 7   ? 9.541   -5.408  36.723  1.00 70.12  ? 7   VAL A CG1   1 
ATOM   53   C  CG2   . VAL A 1 7   ? 7.977   -7.208  36.039  1.00 67.52  ? 7   VAL A CG2   1 
ATOM   54   N  N     . PRO A 1 8   ? 7.602   -2.743  37.589  1.00 69.94  ? 8   PRO A N     1 
ATOM   55   C  CA    . PRO A 1 8   ? 7.808   -1.298  37.450  1.00 71.29  ? 8   PRO A CA    1 
ATOM   56   C  C     . PRO A 1 8   ? 9.026   -1.011  36.587  1.00 69.66  ? 8   PRO A C     1 
ATOM   57   O  O     . PRO A 1 8   ? 9.896   -1.861  36.394  1.00 70.92  ? 8   PRO A O     1 
ATOM   58   C  CB    . PRO A 1 8   ? 8.023   -0.821  38.891  1.00 80.01  ? 8   PRO A CB    1 
ATOM   59   C  CG    . PRO A 1 8   ? 7.483   -1.924  39.755  1.00 78.48  ? 8   PRO A CG    1 
ATOM   60   C  CD    . PRO A 1 8   ? 7.711   -3.187  38.987  1.00 73.10  ? 8   PRO A CD    1 
ATOM   61   N  N     . GLU A 1 9   ? 9.085   0.219   36.076  1.00 75.28  ? 9   GLU A N     1 
ATOM   62   C  CA    . GLU A 1 9   ? 10.085  0.552   35.066  1.00 79.26  ? 9   GLU A CA    1 
ATOM   63   C  C     . GLU A 1 9   ? 11.507  0.386   35.591  1.00 77.91  ? 9   GLU A C     1 
ATOM   64   O  O     . GLU A 1 9   ? 12.366  -0.163  34.893  1.00 77.68  ? 9   GLU A O     1 
ATOM   65   C  CB    . GLU A 1 9   ? 9.873   1.978   34.562  1.00 89.12  ? 9   GLU A CB    1 
ATOM   66   C  CG    . GLU A 1 9   ? 10.561  2.259   33.238  1.00 91.67  ? 9   GLU A CG    1 
ATOM   67   C  CD    . GLU A 1 9   ? 10.972  3.711   33.097  1.00 100.87 ? 9   GLU A CD    1 
ATOM   68   O  OE1   . GLU A 1 9   ? 10.386  4.560   33.806  1.00 107.94 ? 9   GLU A OE1   1 
ATOM   69   O  OE2   . GLU A 1 9   ? 11.873  4.000   32.274  1.00 98.14  ? 9   GLU A OE2   1 
ATOM   70   N  N     . ASP A 1 10  ? 11.782  0.864   36.809  1.00 80.70  ? 10  ASP A N     1 
ATOM   71   C  CA    . ASP A 1 10  ? 13.147  0.803   37.328  1.00 84.13  ? 10  ASP A CA    1 
ATOM   72   C  C     . ASP A 1 10  ? 13.613  -0.639  37.503  1.00 81.44  ? 10  ASP A C     1 
ATOM   73   O  O     . ASP A 1 10  ? 14.783  -0.958  37.253  1.00 82.14  ? 10  ASP A O     1 
ATOM   74   C  CB    . ASP A 1 10  ? 13.247  1.569   38.649  1.00 94.29  ? 10  ASP A CB    1 
ATOM   75   C  CG    . ASP A 1 10  ? 13.385  3.077   38.450  1.00 107.72 ? 10  ASP A CG    1 
ATOM   76   O  OD1   . ASP A 1 10  ? 13.613  3.518   37.299  1.00 108.56 ? 10  ASP A OD1   1 
ATOM   77   O  OD2   . ASP A 1 10  ? 13.276  3.821   39.450  1.00 112.25 ? 10  ASP A OD2   1 
ATOM   78   N  N     . MET A 1 11  ? 12.712  -1.529  37.914  1.00 78.52  ? 11  MET A N     1 
ATOM   79   C  CA    . MET A 1 11  ? 13.091  -2.930  38.042  1.00 72.87  ? 11  MET A CA    1 
ATOM   80   C  C     . MET A 1 11  ? 13.343  -3.549  36.668  1.00 71.59  ? 11  MET A C     1 
ATOM   81   O  O     . MET A 1 11  ? 14.270  -4.356  36.501  1.00 72.04  ? 11  MET A O     1 
ATOM   82   C  CB    . MET A 1 11  ? 12.011  -3.673  38.831  1.00 69.78  ? 11  MET A CB    1 
ATOM   83   C  CG    . MET A 1 11  ? 12.508  -4.856  39.647  1.00 79.14  ? 11  MET A CG    1 
ATOM   84   S  SD    . MET A 1 11  ? 11.160  -5.844  40.327  1.00 89.89  ? 11  MET A SD    1 
ATOM   85   C  CE    . MET A 1 11  ? 10.205  -4.569  41.147  1.00 74.33  ? 11  MET A CE    1 
ATOM   86   N  N     . GLN A 1 12  ? 12.561  -3.136  35.662  1.00 69.93  ? 12  GLN A N     1 
ATOM   87   C  CA    . GLN A 1 12  ? 12.782  -3.599  34.292  1.00 69.24  ? 12  GLN A CA    1 
ATOM   88   C  C     . GLN A 1 12  ? 14.143  -3.145  33.773  1.00 70.09  ? 12  GLN A C     1 
ATOM   89   O  O     . GLN A 1 12  ? 14.841  -3.896  33.078  1.00 70.84  ? 12  GLN A O     1 
ATOM   90   C  CB    . GLN A 1 12  ? 11.670  -3.078  33.374  1.00 69.05  ? 12  GLN A CB    1 
ATOM   91   C  CG    . GLN A 1 12  ? 10.282  -3.670  33.626  1.00 68.81  ? 12  GLN A CG    1 
ATOM   92   C  CD    . GLN A 1 12  ? 9.301   -3.394  32.493  1.00 68.95  ? 12  GLN A CD    1 
ATOM   93   O  OE1   . GLN A 1 12  ? 9.181   -4.179  31.555  1.00 70.19  ? 12  GLN A OE1   1 
ATOM   94   N  NE2   . GLN A 1 12  ? 8.614   -2.263  32.567  1.00 73.54  ? 12  GLN A NE2   1 
ATOM   95   N  N     . ASN A 1 13  ? 14.539  -1.916  34.102  1.00 69.24  ? 13  ASN A N     1 
ATOM   96   C  CA    . ASN A 1 13  ? 15.852  -1.430  33.692  1.00 68.92  ? 13  ASN A CA    1 
ATOM   97   C  C     . ASN A 1 13  ? 16.964  -2.165  34.426  1.00 68.49  ? 13  ASN A C     1 
ATOM   98   O  O     . ASN A 1 13  ? 18.015  -2.454  33.842  1.00 71.34  ? 13  ASN A O     1 
ATOM   99   C  CB    . ASN A 1 13  ? 15.942  0.075   33.930  1.00 72.25  ? 13  ASN A CB    1 
ATOM   100  C  CG    . ASN A 1 13  ? 14.899  0.841   33.145  1.00 79.88  ? 13  ASN A CG    1 
ATOM   101  O  OD1   . ASN A 1 13  ? 14.293  0.300   32.218  1.00 81.07  ? 13  ASN A OD1   1 
ATOM   102  N  ND2   . ASN A 1 13  ? 14.668  2.097   33.521  1.00 84.45  ? 13  ASN A ND2   1 
ATOM   103  N  N     . GLU A 1 14  ? 16.750  -2.484  35.704  1.00 68.36  ? 14  GLU A N     1 
ATOM   104  C  CA    . GLU A 1 14  ? 17.744  -3.257  36.442  1.00 70.48  ? 14  GLU A CA    1 
ATOM   105  C  C     . GLU A 1 14  ? 17.966  -4.620  35.798  1.00 73.11  ? 14  GLU A C     1 
ATOM   106  O  O     . GLU A 1 14  ? 19.109  -5.060  35.623  1.00 74.09  ? 14  GLU A O     1 
ATOM   107  C  CB    . GLU A 1 14  ? 17.312  -3.412  37.898  1.00 75.40  ? 14  GLU A CB    1 
ATOM   108  C  CG    . GLU A 1 14  ? 18.400  -3.959  38.801  1.00 81.42  ? 14  GLU A CG    1 
ATOM   109  C  CD    . GLU A 1 14  ? 17.968  -4.007  40.255  1.00 96.15  ? 14  GLU A CD    1 
ATOM   110  O  OE1   . GLU A 1 14  ? 16.763  -4.225  40.503  1.00 101.20 ? 14  GLU A OE1   1 
ATOM   111  O  OE2   . GLU A 1 14  ? 18.827  -3.823  41.147  1.00 101.15 ? 14  GLU A OE2   1 
ATOM   112  N  N     . ALA A 1 15  ? 16.878  -5.300  35.426  1.00 71.81  ? 15  ALA A N     1 
ATOM   113  C  CA    . ALA A 1 15  ? 17.003  -6.604  34.778  1.00 62.28  ? 15  ALA A CA    1 
ATOM   114  C  C     . ALA A 1 15  ? 17.667  -6.489  33.408  1.00 64.57  ? 15  ALA A C     1 
ATOM   115  O  O     . ALA A 1 15  ? 18.565  -7.274  33.072  1.00 64.81  ? 15  ALA A O     1 
ATOM   116  C  CB    . ALA A 1 15  ? 15.630  -7.263  34.659  1.00 59.91  ? 15  ALA A CB    1 
ATOM   117  N  N     . LEU A 1 16  ? 17.229  -5.520  32.598  1.00 66.00  ? 16  LEU A N     1 
ATOM   118  C  CA    . LEU A 1 16  ? 17.798  -5.350  31.266  1.00 61.18  ? 16  LEU A CA    1 
ATOM   119  C  C     . LEU A 1 16  ? 19.276  -4.987  31.328  1.00 63.37  ? 16  LEU A C     1 
ATOM   120  O  O     . LEU A 1 16  ? 20.038  -5.345  30.423  1.00 65.01  ? 16  LEU A O     1 
ATOM   121  C  CB    . LEU A 1 16  ? 17.010  -4.288  30.499  1.00 58.20  ? 16  LEU A CB    1 
ATOM   122  C  CG    . LEU A 1 16  ? 15.754  -4.760  29.757  1.00 60.35  ? 16  LEU A CG    1 
ATOM   123  C  CD1   . LEU A 1 16  ? 15.085  -3.604  29.034  1.00 66.26  ? 16  LEU A CD1   1 
ATOM   124  C  CD2   . LEU A 1 16  ? 16.097  -5.859  28.764  1.00 62.61  ? 16  LEU A CD2   1 
ATOM   125  N  N     . SER A 1 17  ? 19.707  -4.302  32.389  1.00 64.93  ? 17  SER A N     1 
ATOM   126  C  CA    . SER A 1 17  ? 21.120  -3.971  32.527  1.00 73.65  ? 17  SER A CA    1 
ATOM   127  C  C     . SER A 1 17  ? 21.924  -5.165  33.036  1.00 72.56  ? 17  SER A C     1 
ATOM   128  O  O     . SER A 1 17  ? 23.023  -5.441  32.531  1.00 75.48  ? 17  SER A O     1 
ATOM   129  C  CB    . SER A 1 17  ? 21.281  -2.767  33.458  1.00 72.73  ? 17  SER A CB    1 
ATOM   130  O  OG    . SER A 1 17  ? 22.444  -2.020  33.139  1.00 76.55  ? 17  SER A OG    1 
ATOM   131  N  N     . LEU A 1 18  ? 21.389  -5.881  34.029  1.00 67.64  ? 18  LEU A N     1 
ATOM   132  C  CA    . LEU A 1 18  ? 22.031  -7.110  34.476  1.00 66.48  ? 18  LEU A CA    1 
ATOM   133  C  C     . LEU A 1 18  ? 22.209  -8.085  33.323  1.00 67.90  ? 18  LEU A C     1 
ATOM   134  O  O     . LEU A 1 18  ? 23.194  -8.827  33.289  1.00 70.84  ? 18  LEU A O     1 
ATOM   135  C  CB    . LEU A 1 18  ? 21.215  -7.750  35.599  1.00 62.23  ? 18  LEU A CB    1 
ATOM   136  C  CG    . LEU A 1 18  ? 21.597  -9.179  35.973  1.00 63.96  ? 18  LEU A CG    1 
ATOM   137  C  CD1   . LEU A 1 18  ? 22.954  -9.165  36.653  1.00 71.04  ? 18  LEU A CD1   1 
ATOM   138  C  CD2   . LEU A 1 18  ? 20.559  -9.814  36.888  1.00 63.80  ? 18  LEU A CD2   1 
ATOM   139  N  N     . LEU A 1 19  ? 21.281  -8.084  32.364  1.00 64.34  ? 19  LEU A N     1 
ATOM   140  C  CA    . LEU A 1 19  ? 21.425  -8.929  31.181  1.00 64.70  ? 19  LEU A CA    1 
ATOM   141  C  C     . LEU A 1 19  ? 22.701  -8.589  30.410  1.00 70.26  ? 19  LEU A C     1 
ATOM   142  O  O     . LEU A 1 19  ? 23.482  -9.482  30.042  1.00 71.90  ? 19  LEU A O     1 
ATOM   143  C  CB    . LEU A 1 19  ? 20.186  -8.781  30.294  1.00 62.83  ? 19  LEU A CB    1 
ATOM   144  C  CG    . LEU A 1 19  ? 19.946  -9.785  29.162  1.00 61.11  ? 19  LEU A CG    1 
ATOM   145  C  CD1   . LEU A 1 19  ? 20.005  -11.215 29.664  1.00 63.05  ? 19  LEU A CD1   1 
ATOM   146  C  CD2   . LEU A 1 19  ? 18.611  -9.516  28.493  1.00 51.68  ? 19  LEU A CD2   1 
ATOM   147  N  N     . GLU A 1 20  ? 22.943  -7.296  30.171  1.00 71.69  ? 20  GLU A N     1 
ATOM   148  C  CA    . GLU A 1 20  ? 24.131  -6.909  29.416  1.00 75.96  ? 20  GLU A CA    1 
ATOM   149  C  C     . GLU A 1 20  ? 25.406  -7.156  30.206  1.00 73.56  ? 20  GLU A C     1 
ATOM   150  O  O     . GLU A 1 20  ? 26.448  -7.461  29.616  1.00 75.40  ? 20  GLU A O     1 
ATOM   151  C  CB    . GLU A 1 20  ? 24.052  -5.444  28.996  1.00 72.74  ? 20  GLU A CB    1 
ATOM   152  C  CG    . GLU A 1 20  ? 22.863  -5.124  28.110  1.00 85.97  ? 20  GLU A CG    1 
ATOM   153  C  CD    . GLU A 1 20  ? 23.224  -4.197  26.956  1.00 94.62  ? 20  GLU A CD    1 
ATOM   154  O  OE1   . GLU A 1 20  ? 24.286  -4.424  26.330  1.00 89.31  ? 20  GLU A OE1   1 
ATOM   155  O  OE2   . GLU A 1 20  ? 22.457  -3.238  26.689  1.00 93.35  ? 20  GLU A OE2   1 
ATOM   156  N  N     . LYS A 1 21  ? 25.351  -7.028  31.532  1.00 70.83  ? 21  LYS A N     1 
ATOM   157  C  CA    . LYS A 1 21  ? 26.545  -7.319  32.321  1.00 69.90  ? 21  LYS A CA    1 
ATOM   158  C  C     . LYS A 1 21  ? 26.831  -8.817  32.370  1.00 74.08  ? 21  LYS A C     1 
ATOM   159  O  O     . LYS A 1 21  ? 27.998  -9.226  32.359  1.00 73.52  ? 21  LYS A O     1 
ATOM   160  C  CB    . LYS A 1 21  ? 26.406  -6.739  33.730  1.00 73.78  ? 21  LYS A CB    1 
ATOM   161  C  CG    . LYS A 1 21  ? 25.769  -5.356  33.762  1.00 73.96  ? 21  LYS A CG    1 
ATOM   162  C  CD    . LYS A 1 21  ? 26.101  -4.577  35.033  1.00 81.64  ? 21  LYS A CD    1 
ATOM   163  C  CE    . LYS A 1 21  ? 25.166  -4.927  36.180  1.00 85.67  ? 21  LYS A CE    1 
ATOM   164  N  NZ    . LYS A 1 21  ? 24.605  -3.725  36.856  1.00 79.42  ? 21  LYS A NZ    1 
ATOM   165  N  N     . VAL A 1 22  ? 25.783  -9.644  32.397  1.00 77.99  ? 22  VAL A N     1 
ATOM   166  C  CA    . VAL A 1 22  ? 25.945  -11.094 32.402  1.00 77.92  ? 22  VAL A CA    1 
ATOM   167  C  C     . VAL A 1 22  ? 26.463  -11.590 31.058  1.00 76.04  ? 22  VAL A C     1 
ATOM   168  O  O     . VAL A 1 22  ? 27.149  -12.618 30.998  1.00 71.80  ? 22  VAL A O     1 
ATOM   169  C  CB    . VAL A 1 22  ? 24.607  -11.760 32.789  1.00 70.79  ? 22  VAL A CB    1 
ATOM   170  C  CG1   . VAL A 1 22  ? 24.548  -13.211 32.332  1.00 75.23  ? 22  VAL A CG1   1 
ATOM   171  C  CG2   . VAL A 1 22  ? 24.390  -11.676 34.288  1.00 71.82  ? 22  VAL A CG2   1 
ATOM   172  N  N     . ARG A 1 23  ? 26.149  -10.875 29.970  1.00 76.17  ? 23  ARG A N     1 
ATOM   173  C  CA    . ARG A 1 23  ? 26.619  -11.255 28.636  1.00 76.07  ? 23  ARG A CA    1 
ATOM   174  C  C     . ARG A 1 23  ? 28.040  -11.809 28.617  1.00 85.45  ? 23  ARG A C     1 
ATOM   175  O  O     . ARG A 1 23  ? 28.293  -12.875 28.046  1.00 90.85  ? 23  ARG A O     1 
ATOM   176  C  CB    . ARG A 1 23  ? 26.536  -10.055 27.696  1.00 78.31  ? 23  ARG A CB    1 
ATOM   177  C  CG    . ARG A 1 23  ? 25.142  -9.736  27.226  1.00 87.70  ? 23  ARG A CG    1 
ATOM   178  C  CD    . ARG A 1 23  ? 25.206  -8.960  25.925  1.00 84.96  ? 23  ARG A CD    1 
ATOM   179  N  NE    . ARG A 1 23  ? 25.345  -7.530  26.168  1.00 84.21  ? 23  ARG A NE    1 
ATOM   180  C  CZ    . ARG A 1 23  ? 26.342  -6.795  25.697  1.00 83.43  ? 23  ARG A CZ    1 
ATOM   181  N  NH1   . ARG A 1 23  ? 27.279  -7.322  24.928  1.00 82.00  ? 23  ARG A NH1   1 
ATOM   182  N  NH2   . ARG A 1 23  ? 26.399  -5.501  26.003  1.00 85.49  ? 23  ARG A NH2   1 
ATOM   183  N  N     . GLU A 1 24  ? 28.982  -11.108 29.248  1.00 85.90  ? 24  GLU A N     1 
ATOM   184  C  CA    . GLU A 1 24  ? 30.391  -11.486 29.160  1.00 88.00  ? 24  GLU A CA    1 
ATOM   185  C  C     . GLU A 1 24  ? 30.737  -12.728 29.979  1.00 82.10  ? 24  GLU A C     1 
ATOM   186  O  O     . GLU A 1 24  ? 31.119  -13.761 29.417  1.00 76.15  ? 24  GLU A O     1 
ATOM   187  C  CB    . GLU A 1 24  ? 31.278  -10.317 29.592  1.00 92.43  ? 24  GLU A CB    1 
ATOM   188  C  CG    . GLU A 1 24  ? 31.546  -9.309  28.490  1.00 104.71 ? 24  GLU A CG    1 
ATOM   189  C  CD    . GLU A 1 24  ? 32.561  -9.816  27.483  1.00 109.83 ? 24  GLU A CD    1 
ATOM   190  O  OE1   . GLU A 1 24  ? 33.774  -9.736  27.771  1.00 98.66  ? 24  GLU A OE1   1 
ATOM   191  O  OE2   . GLU A 1 24  ? 32.145  -10.296 26.400  1.00 108.68 ? 24  GLU A OE2   1 
ATOM   192  N  N     . SER A 1 25  ? 30.616  -12.636 31.304  1.00 78.90  ? 25  SER A N     1 
ATOM   193  C  CA    . SER A 1 25  ? 31.077  -13.687 32.204  1.00 75.19  ? 25  SER A CA    1 
ATOM   194  C  C     . SER A 1 25  ? 30.078  -14.828 32.390  1.00 80.29  ? 25  SER A C     1 
ATOM   195  O  O     . SER A 1 25  ? 30.450  -15.859 32.963  1.00 70.36  ? 25  SER A O     1 
ATOM   196  C  CB    . SER A 1 25  ? 31.420  -13.071 33.560  1.00 75.72  ? 25  SER A CB    1 
ATOM   197  O  OG    . SER A 1 25  ? 30.242  -12.672 34.237  1.00 81.97  ? 25  SER A OG    1 
ATOM   198  N  N     . GLY A 1 26  ? 28.832  -14.681 31.926  1.00 82.35  ? 26  GLY A N     1 
ATOM   199  C  CA    . GLY A 1 26  ? 27.820  -15.702 32.056  1.00 73.83  ? 26  GLY A CA    1 
ATOM   200  C  C     . GLY A 1 26  ? 27.451  -16.341 30.731  1.00 74.30  ? 26  GLY A C     1 
ATOM   201  O  O     . GLY A 1 26  ? 28.194  -16.268 29.743  1.00 76.12  ? 26  GLY A O     1 
ATOM   202  N  N     . LYS A 1 27  ? 26.279  -16.984 30.712  1.00 71.51  ? 27  LYS A N     1 
ATOM   203  C  CA    . LYS A 1 27  ? 25.736  -17.621 29.513  1.00 67.44  ? 27  LYS A CA    1 
ATOM   204  C  C     . LYS A 1 27  ? 24.262  -17.264 29.373  1.00 67.39  ? 27  LYS A C     1 
ATOM   205  O  O     . LYS A 1 27  ? 23.482  -17.444 30.315  1.00 67.59  ? 27  LYS A O     1 
ATOM   206  C  CB    . LYS A 1 27  ? 25.895  -19.145 29.557  1.00 69.37  ? 27  LYS A CB    1 
ATOM   207  C  CG    . LYS A 1 27  ? 24.821  -19.906 28.779  1.00 69.98  ? 27  LYS A CG    1 
ATOM   208  C  CD    . LYS A 1 27  ? 25.279  -21.307 28.397  1.00 68.05  ? 27  LYS A CD    1 
ATOM   209  C  CE    . LYS A 1 27  ? 26.058  -21.340 27.100  1.00 66.29  ? 27  LYS A CE    1 
ATOM   210  N  NZ    . LYS A 1 27  ? 26.184  -22.754 26.630  1.00 70.98  ? 27  LYS A NZ    1 
ATOM   211  N  N     . VAL A 1 28  ? 23.886  -16.779 28.190  1.00 63.53  ? 28  VAL A N     1 
ATOM   212  C  CA    . VAL A 1 28  ? 22.547  -16.270 27.912  1.00 60.77  ? 28  VAL A CA    1 
ATOM   213  C  C     . VAL A 1 28  ? 22.045  -16.896 26.614  1.00 62.49  ? 28  VAL A C     1 
ATOM   214  O  O     . VAL A 1 28  ? 22.805  -17.030 25.650  1.00 67.57  ? 28  VAL A O     1 
ATOM   215  C  CB    . VAL A 1 28  ? 22.562  -14.726 27.818  1.00 55.44  ? 28  VAL A CB    1 
ATOM   216  C  CG1   . VAL A 1 28  ? 21.239  -14.186 27.305  1.00 58.82  ? 28  VAL A CG1   1 
ATOM   217  C  CG2   . VAL A 1 28  ? 22.903  -14.114 29.169  1.00 60.17  ? 28  VAL A CG2   1 
ATOM   218  N  N     . LYS A 1 29  ? 20.772  -17.294 26.592  1.00 60.76  ? 29  LYS A N     1 
ATOM   219  C  CA    . LYS A 1 29  ? 20.119  -17.770 25.380  1.00 57.04  ? 29  LYS A CA    1 
ATOM   220  C  C     . LYS A 1 29  ? 19.005  -16.811 24.984  1.00 56.00  ? 29  LYS A C     1 
ATOM   221  O  O     . LYS A 1 29  ? 18.390  -16.163 25.835  1.00 61.06  ? 29  LYS A O     1 
ATOM   222  C  CB    . LYS A 1 29  ? 19.539  -19.171 25.571  1.00 57.50  ? 29  LYS A CB    1 
ATOM   223  C  CG    . LYS A 1 29  ? 20.543  -20.183 26.061  1.00 65.04  ? 29  LYS A CG    1 
ATOM   224  C  CD    . LYS A 1 29  ? 21.053  -21.059 24.947  1.00 70.11  ? 29  LYS A CD    1 
ATOM   225  C  CE    . LYS A 1 29  ? 21.469  -22.421 25.475  1.00 76.06  ? 29  LYS A CE    1 
ATOM   226  N  NZ    . LYS A 1 29  ? 22.517  -23.029 24.616  1.00 84.72  ? 29  LYS A NZ    1 
ATOM   227  N  N     . LYS A 1 30  ? 18.738  -16.731 23.689  1.00 55.24  ? 30  LYS A N     1 
ATOM   228  C  CA    . LYS A 1 30  ? 17.726  -15.825 23.171  1.00 58.56  ? 30  LYS A CA    1 
ATOM   229  C  C     . LYS A 1 30  ? 16.805  -16.585 22.228  1.00 57.60  ? 30  LYS A C     1 
ATOM   230  O  O     . LYS A 1 30  ? 17.269  -17.353 21.380  1.00 59.42  ? 30  LYS A O     1 
ATOM   231  C  CB    . LYS A 1 30  ? 18.374  -14.632 22.447  1.00 64.04  ? 30  LYS A CB    1 
ATOM   232  C  CG    . LYS A 1 30  ? 17.421  -13.815 21.575  1.00 64.31  ? 30  LYS A CG    1 
ATOM   233  C  CD    . LYS A 1 30  ? 18.148  -12.717 20.810  1.00 58.46  ? 30  LYS A CD    1 
ATOM   234  C  CE    . LYS A 1 30  ? 19.569  -13.151 20.462  1.00 60.16  ? 30  LYS A CE    1 
ATOM   235  N  NZ    . LYS A 1 30  ? 20.234  -12.182 19.552  1.00 69.77  ? 30  LYS A NZ    1 
ATOM   236  N  N     . GLY A 1 31  ? 15.509  -16.367 22.374  1.00 55.62  ? 31  GLY A N     1 
ATOM   237  C  CA    . GLY A 1 31  ? 14.520  -17.017 21.543  1.00 54.60  ? 31  GLY A CA    1 
ATOM   238  C  C     . GLY A 1 31  ? 13.657  -17.979 22.344  1.00 56.82  ? 31  GLY A C     1 
ATOM   239  O  O     . GLY A 1 31  ? 14.045  -18.485 23.399  1.00 60.77  ? 31  GLY A O     1 
ATOM   240  N  N     . THR A 1 32  ? 12.464  -18.244 21.813  1.00 55.36  ? 32  THR A N     1 
ATOM   241  C  CA    . THR A 1 32  ? 11.484  -19.009 22.577  1.00 60.78  ? 32  THR A CA    1 
ATOM   242  C  C     . THR A 1 32  ? 11.836  -20.493 22.616  1.00 60.35  ? 32  THR A C     1 
ATOM   243  O  O     . THR A 1 32  ? 11.591  -21.171 23.622  1.00 54.10  ? 32  THR A O     1 
ATOM   244  C  CB    . THR A 1 32  ? 10.088  -18.797 21.994  1.00 59.55  ? 32  THR A CB    1 
ATOM   245  O  OG1   . THR A 1 32  ? 9.877   -17.396 21.783  1.00 64.02  ? 32  THR A OG1   1 
ATOM   246  C  CG2   . THR A 1 32  ? 9.028   -19.314 22.953  1.00 57.80  ? 32  THR A CG2   1 
ATOM   247  N  N     . ASN A 1 33  ? 12.424  -21.012 21.540  1.00 58.14  ? 33  ASN A N     1 
ATOM   248  C  CA    . ASN A 1 33  ? 12.774  -22.426 21.495  1.00 59.70  ? 33  ASN A CA    1 
ATOM   249  C  C     . ASN A 1 33  ? 13.784  -22.767 22.579  1.00 60.37  ? 33  ASN A C     1 
ATOM   250  O  O     . ASN A 1 33  ? 13.525  -23.597 23.464  1.00 61.33  ? 33  ASN A O     1 
ATOM   251  C  CB    . ASN A 1 33  ? 13.343  -22.770 20.120  1.00 62.15  ? 33  ASN A CB    1 
ATOM   252  C  CG    . ASN A 1 33  ? 12.279  -22.819 19.057  1.00 65.71  ? 33  ASN A CG    1 
ATOM   253  O  OD1   . ASN A 1 33  ? 11.180  -22.295 19.246  1.00 70.07  ? 33  ASN A OD1   1 
ATOM   254  N  ND2   . ASN A 1 33  ? 12.601  -23.430 17.919  1.00 63.83  ? 33  ASN A ND2   1 
ATOM   255  N  N     . SER A 1 34  ? 14.955  -22.133 22.508  1.00 57.52  ? 34  SER A N     1 
ATOM   256  C  CA    . SER A 1 34  ? 16.018  -22.429 23.453  1.00 58.01  ? 34  SER A CA    1 
ATOM   257  C  C     . SER A 1 34  ? 15.623  -22.063 24.875  1.00 58.24  ? 34  SER A C     1 
ATOM   258  O  O     . SER A 1 34  ? 15.995  -22.778 25.808  1.00 58.35  ? 34  SER A O     1 
ATOM   259  C  CB    . SER A 1 34  ? 17.306  -21.720 23.028  1.00 57.19  ? 34  SER A CB    1 
ATOM   260  O  OG    . SER A 1 34  ? 17.066  -20.377 22.653  1.00 58.71  ? 34  SER A OG    1 
ATOM   261  N  N     . THR A 1 35  ? 14.850  -20.988 25.062  1.00 54.81  ? 35  THR A N     1 
ATOM   262  C  CA    . THR A 1 35  ? 14.432  -20.604 26.410  1.00 57.62  ? 35  THR A CA    1 
ATOM   263  C  C     . THR A 1 35  ? 13.482  -21.630 27.012  1.00 63.41  ? 35  THR A C     1 
ATOM   264  O  O     . THR A 1 35  ? 13.641  -22.031 28.174  1.00 69.03  ? 35  THR A O     1 
ATOM   265  C  CB    . THR A 1 35  ? 13.788  -19.220 26.397  1.00 54.05  ? 35  THR A CB    1 
ATOM   266  O  OG1   . THR A 1 35  ? 14.757  -18.257 25.971  1.00 56.10  ? 35  THR A OG1   1 
ATOM   267  C  CG2   . THR A 1 35  ? 13.271  -18.850 27.773  1.00 59.72  ? 35  THR A CG2   1 
ATOM   268  N  N     . THR A 1 36  ? 12.483  -22.067 26.241  1.00 61.73  ? 36  THR A N     1 
ATOM   269  C  CA    . THR A 1 36  ? 11.585  -23.106 26.729  1.00 63.45  ? 36  THR A CA    1 
ATOM   270  C  C     . THR A 1 36  ? 12.364  -24.370 27.077  1.00 61.66  ? 36  THR A C     1 
ATOM   271  O  O     . THR A 1 36  ? 12.156  -24.966 28.143  1.00 62.42  ? 36  THR A O     1 
ATOM   272  C  CB    . THR A 1 36  ? 10.508  -23.402 25.682  1.00 63.64  ? 36  THR A CB    1 
ATOM   273  O  OG1   . THR A 1 36  ? 9.880   -22.181 25.275  1.00 57.55  ? 36  THR A OG1   1 
ATOM   274  C  CG2   . THR A 1 36  ? 9.448   -24.319 26.267  1.00 64.22  ? 36  THR A CG2   1 
ATOM   275  N  N     . LEU A 1 37  ? 13.277  -24.785 26.192  1.00 59.31  ? 37  LEU A N     1 
ATOM   276  C  CA    . LEU A 1 37  ? 14.116  -25.942 26.488  1.00 62.94  ? 37  LEU A CA    1 
ATOM   277  C  C     . LEU A 1 37  ? 14.905  -25.742 27.774  1.00 67.80  ? 37  LEU A C     1 
ATOM   278  O  O     . LEU A 1 37  ? 14.938  -26.626 28.635  1.00 70.88  ? 37  LEU A O     1 
ATOM   279  C  CB    . LEU A 1 37  ? 15.065  -26.221 25.327  1.00 68.76  ? 37  LEU A CB    1 
ATOM   280  C  CG    . LEU A 1 37  ? 14.461  -26.970 24.148  1.00 71.11  ? 37  LEU A CG    1 
ATOM   281  C  CD1   . LEU A 1 37  ? 15.199  -26.627 22.861  1.00 70.71  ? 37  LEU A CD1   1 
ATOM   282  C  CD2   . LEU A 1 37  ? 14.538  -28.460 24.430  1.00 75.92  ? 37  LEU A CD2   1 
ATOM   283  N  N     . ALA A 1 38  ? 15.547  -24.580 27.921  1.00 65.21  ? 38  ALA A N     1 
ATOM   284  C  CA    . ALA A 1 38  ? 16.378  -24.326 29.092  1.00 64.99  ? 38  ALA A CA    1 
ATOM   285  C  C     . ALA A 1 38  ? 15.564  -24.368 30.374  1.00 62.60  ? 38  ALA A C     1 
ATOM   286  O  O     . ALA A 1 38  ? 16.075  -24.796 31.416  1.00 66.68  ? 38  ALA A O     1 
ATOM   287  C  CB    . ALA A 1 38  ? 17.084  -22.978 28.955  1.00 60.26  ? 38  ALA A CB    1 
ATOM   288  N  N     . VAL A 1 39  ? 14.303  -23.937 30.323  1.00 56.08  ? 39  VAL A N     1 
ATOM   289  C  CA    . VAL A 1 39  ? 13.473  -24.026 31.519  1.00 62.57  ? 39  VAL A CA    1 
ATOM   290  C  C     . VAL A 1 39  ? 13.097  -25.474 31.801  1.00 67.09  ? 39  VAL A C     1 
ATOM   291  O  O     . VAL A 1 39  ? 13.178  -25.938 32.947  1.00 60.74  ? 39  VAL A O     1 
ATOM   292  C  CB    . VAL A 1 39  ? 12.227  -23.132 31.395  1.00 61.21  ? 39  VAL A CB    1 
ATOM   293  C  CG1   . VAL A 1 39  ? 11.410  -23.206 32.673  1.00 65.76  ? 39  VAL A CG1   1 
ATOM   294  C  CG2   . VAL A 1 39  ? 12.630  -21.701 31.118  1.00 63.28  ? 39  VAL A CG2   1 
ATOM   295  N  N     . SER A 1 40  ? 12.685  -26.212 30.765  1.00 70.62  ? 40  SER A N     1 
ATOM   296  C  CA    . SER A 1 40  ? 12.290  -27.602 30.974  1.00 65.56  ? 40  SER A CA    1 
ATOM   297  C  C     . SER A 1 40  ? 13.444  -28.445 31.505  1.00 60.23  ? 40  SER A C     1 
ATOM   298  O  O     . SER A 1 40  ? 13.222  -29.345 32.321  1.00 69.84  ? 40  SER A O     1 
ATOM   299  C  CB    . SER A 1 40  ? 11.737  -28.202 29.679  1.00 61.89  ? 40  SER A CB    1 
ATOM   300  O  OG    . SER A 1 40  ? 12.767  -28.474 28.749  1.00 66.43  ? 40  SER A OG    1 
ATOM   301  N  N     . ARG A 1 41  ? 14.675  -28.156 31.090  1.00 56.92  ? 41  ARG A N     1 
ATOM   302  C  CA    . ARG A 1 41  ? 15.839  -28.904 31.544  1.00 60.76  ? 41  ARG A CA    1 
ATOM   303  C  C     . ARG A 1 41  ? 16.401  -28.386 32.863  1.00 63.17  ? 41  ARG A C     1 
ATOM   304  O  O     . ARG A 1 41  ? 17.475  -28.831 33.280  1.00 64.07  ? 41  ARG A O     1 
ATOM   305  C  CB    . ARG A 1 41  ? 16.925  -28.894 30.463  1.00 64.01  ? 41  ARG A CB    1 
ATOM   306  C  CG    . ARG A 1 41  ? 16.377  -29.161 29.063  1.00 71.35  ? 41  ARG A CG    1 
ATOM   307  C  CD    . ARG A 1 41  ? 17.456  -29.230 27.988  1.00 81.49  ? 41  ARG A CD    1 
ATOM   308  N  NE    . ARG A 1 41  ? 17.053  -30.072 26.865  1.00 89.10  ? 41  ARG A NE    1 
ATOM   309  C  CZ    . ARG A 1 41  ? 17.778  -30.256 25.769  1.00 96.12  ? 41  ARG A CZ    1 
ATOM   310  N  NH1   . ARG A 1 41  ? 18.962  -29.685 25.620  1.00 99.81  ? 41  ARG A NH1   1 
ATOM   311  N  NH2   . ARG A 1 41  ? 17.302  -31.032 24.797  1.00 98.16  ? 41  ARG A NH2   1 
ATOM   312  N  N     . GLY A 1 42  ? 15.703  -27.469 33.528  1.00 62.43  ? 42  GLY A N     1 
ATOM   313  C  CA    . GLY A 1 42  ? 16.191  -26.931 34.787  1.00 57.52  ? 42  GLY A CA    1 
ATOM   314  C  C     . GLY A 1 42  ? 17.509  -26.198 34.682  1.00 65.05  ? 42  GLY A C     1 
ATOM   315  O  O     . GLY A 1 42  ? 18.315  -26.245 35.617  1.00 73.99  ? 42  GLY A O     1 
ATOM   316  N  N     . LEU A 1 43  ? 17.754  -25.514 33.566  1.00 61.43  ? 43  LEU A N     1 
ATOM   317  C  CA    . LEU A 1 43  ? 18.993  -24.771 33.390  1.00 63.58  ? 43  LEU A CA    1 
ATOM   318  C  C     . LEU A 1 43  ? 18.840  -23.268 33.541  1.00 64.24  ? 43  LEU A C     1 
ATOM   319  O  O     . LEU A 1 43  ? 19.809  -22.604 33.909  1.00 73.81  ? 43  LEU A O     1 
ATOM   320  C  CB    . LEU A 1 43  ? 19.612  -25.068 32.018  1.00 63.68  ? 43  LEU A CB    1 
ATOM   321  C  CG    . LEU A 1 43  ? 20.012  -26.524 31.766  1.00 67.81  ? 43  LEU A CG    1 
ATOM   322  C  CD1   . LEU A 1 43  ? 20.357  -26.735 30.310  1.00 67.03  ? 43  LEU A CD1   1 
ATOM   323  C  CD2   . LEU A 1 43  ? 21.178  -26.925 32.661  1.00 72.33  ? 43  LEU A CD2   1 
ATOM   324  N  N     . ALA A 1 44  ? 17.658  -22.712 33.294  1.00 56.51  ? 44  ALA A N     1 
ATOM   325  C  CA    . ALA A 1 44  ? 17.513  -21.262 33.264  1.00 58.41  ? 44  ALA A CA    1 
ATOM   326  C  C     . ALA A 1 44  ? 17.604  -20.686 34.672  1.00 60.11  ? 44  ALA A C     1 
ATOM   327  O  O     . ALA A 1 44  ? 16.861  -21.095 35.568  1.00 53.23  ? 44  ALA A O     1 
ATOM   328  C  CB    . ALA A 1 44  ? 16.190  -20.873 32.614  1.00 56.36  ? 44  ALA A CB    1 
ATOM   329  N  N     . LYS A 1 45  ? 18.521  -19.736 34.867  1.00 67.10  ? 45  LYS A N     1 
ATOM   330  C  CA    . LYS A 1 45  ? 18.562  -19.000 36.125  1.00 61.44  ? 45  LYS A CA    1 
ATOM   331  C  C     . LYS A 1 45  ? 17.439  -17.975 36.188  1.00 57.11  ? 45  LYS A C     1 
ATOM   332  O  O     . LYS A 1 45  ? 16.756  -17.859 37.208  1.00 59.30  ? 45  LYS A O     1 
ATOM   333  C  CB    . LYS A 1 45  ? 19.916  -18.307 36.309  1.00 63.05  ? 45  LYS A CB    1 
ATOM   334  C  CG    . LYS A 1 45  ? 21.085  -19.231 36.599  1.00 71.94  ? 45  LYS A CG    1 
ATOM   335  C  CD    . LYS A 1 45  ? 21.143  -19.661 38.052  1.00 80.74  ? 45  LYS A CD    1 
ATOM   336  C  CE    . LYS A 1 45  ? 21.768  -21.045 38.191  1.00 85.10  ? 45  LYS A CE    1 
ATOM   337  N  NZ    . LYS A 1 45  ? 20.816  -22.154 37.876  1.00 81.49  ? 45  LYS A NZ    1 
ATOM   338  N  N     . LEU A 1 46  ? 17.227  -17.225 35.106  1.00 60.36  ? 46  LEU A N     1 
ATOM   339  C  CA    . LEU A 1 46  ? 16.207  -16.176 35.118  1.00 54.81  ? 46  LEU A CA    1 
ATOM   340  C  C     . LEU A 1 46  ? 15.758  -15.898 33.693  1.00 58.74  ? 46  LEU A C     1 
ATOM   341  O  O     . LEU A 1 46  ? 16.596  -15.626 32.831  1.00 64.16  ? 46  LEU A O     1 
ATOM   342  C  CB    . LEU A 1 46  ? 16.752  -14.891 35.752  1.00 51.32  ? 46  LEU A CB    1 
ATOM   343  C  CG    . LEU A 1 46  ? 15.984  -13.600 35.449  1.00 54.38  ? 46  LEU A CG    1 
ATOM   344  C  CD1   . LEU A 1 46  ? 14.679  -13.536 36.216  1.00 57.34  ? 46  LEU A CD1   1 
ATOM   345  C  CD2   . LEU A 1 46  ? 16.836  -12.373 35.717  1.00 56.37  ? 46  LEU A CD2   1 
ATOM   346  N  N     . VAL A 1 47  ? 14.451  -15.938 33.436  1.00 56.65  ? 47  VAL A N     1 
ATOM   347  C  CA    . VAL A 1 47  ? 13.954  -15.772 32.071  1.00 60.35  ? 47  VAL A CA    1 
ATOM   348  C  C     . VAL A 1 47  ? 13.269  -14.417 31.917  1.00 62.55  ? 47  VAL A C     1 
ATOM   349  O  O     . VAL A 1 47  ? 12.617  -13.914 32.842  1.00 59.50  ? 47  VAL A O     1 
ATOM   350  C  CB    . VAL A 1 47  ? 13.018  -16.920 31.630  1.00 54.06  ? 47  VAL A CB    1 
ATOM   351  C  CG1   . VAL A 1 47  ? 13.709  -18.260 31.802  1.00 61.29  ? 47  VAL A CG1   1 
ATOM   352  C  CG2   . VAL A 1 47  ? 11.719  -16.891 32.366  1.00 58.68  ? 47  VAL A CG2   1 
ATOM   353  N  N     . TYR A 1 48  ? 13.442  -13.830 30.733  1.00 65.96  ? 48  TYR A N     1 
ATOM   354  C  CA    . TYR A 1 48  ? 12.854  -12.557 30.338  1.00 53.93  ? 48  TYR A CA    1 
ATOM   355  C  C     . TYR A 1 48  ? 11.809  -12.805 29.258  1.00 56.63  ? 48  TYR A C     1 
ATOM   356  O  O     . TYR A 1 48  ? 12.078  -13.517 28.283  1.00 54.39  ? 48  TYR A O     1 
ATOM   357  C  CB    . TYR A 1 48  ? 13.922  -11.611 29.788  1.00 54.69  ? 48  TYR A CB    1 
ATOM   358  C  CG    . TYR A 1 48  ? 15.068  -11.282 30.710  1.00 53.65  ? 48  TYR A CG    1 
ATOM   359  C  CD1   . TYR A 1 48  ? 15.986  -12.247 31.087  1.00 53.08  ? 48  TYR A CD1   1 
ATOM   360  C  CD2   . TYR A 1 48  ? 15.271  -9.981  31.144  1.00 56.99  ? 48  TYR A CD2   1 
ATOM   361  C  CE1   . TYR A 1 48  ? 17.044  -11.929 31.909  1.00 60.76  ? 48  TYR A CE1   1 
ATOM   362  C  CE2   . TYR A 1 48  ? 16.328  -9.654  31.959  1.00 56.89  ? 48  TYR A CE2   1 
ATOM   363  C  CZ    . TYR A 1 48  ? 17.212  -10.629 32.341  1.00 59.21  ? 48  TYR A CZ    1 
ATOM   364  O  OH    . TYR A 1 48  ? 18.266  -10.297 33.161  1.00 59.84  ? 48  TYR A OH    1 
ATOM   365  N  N     . ILE A 1 49  ? 10.634  -12.202 29.415  1.00 55.27  ? 49  ILE A N     1 
ATOM   366  C  CA    . ILE A 1 49  ? 9.543   -12.332 28.456  1.00 54.02  ? 49  ILE A CA    1 
ATOM   367  C  C     . ILE A 1 49  ? 9.191   -10.953 27.932  1.00 55.18  ? 49  ILE A C     1 
ATOM   368  O  O     . ILE A 1 49  ? 9.020   -10.016 28.717  1.00 58.19  ? 49  ILE A O     1 
ATOM   369  C  CB    . ILE A 1 49  ? 8.306   -13.001 29.079  1.00 53.27  ? 49  ILE A CB    1 
ATOM   370  C  CG1   . ILE A 1 49  ? 8.723   -14.183 29.954  1.00 50.91  ? 49  ILE A CG1   1 
ATOM   371  C  CG2   . ILE A 1 49  ? 7.345   -13.426 27.998  1.00 58.78  ? 49  ILE A CG2   1 
ATOM   372  C  CD1   . ILE A 1 49  ? 7.661   -14.650 30.914  1.00 57.54  ? 49  ILE A CD1   1 
ATOM   373  N  N     . ALA A 1 50  ? 9.076   -10.831 26.613  1.00 57.01  ? 50  ALA A N     1 
ATOM   374  C  CA    . ALA A 1 50  ? 8.708   -9.564  25.996  1.00 60.76  ? 50  ALA A CA    1 
ATOM   375  C  C     . ALA A 1 50  ? 7.206   -9.318  26.115  1.00 65.62  ? 50  ALA A C     1 
ATOM   376  O  O     . ALA A 1 50  ? 6.400   -10.252 26.127  1.00 67.57  ? 50  ALA A O     1 
ATOM   377  C  CB    . ALA A 1 50  ? 9.125   -9.537  24.525  1.00 54.62  ? 50  ALA A CB    1 
ATOM   378  N  N     . GLU A 1 51  ? 6.834   -8.038  26.198  1.00 64.85  ? 51  GLU A N     1 
ATOM   379  C  CA    . GLU A 1 51  ? 5.431   -7.666  26.345  1.00 64.83  ? 51  GLU A CA    1 
ATOM   380  C  C     . GLU A 1 51  ? 4.728   -7.420  25.013  1.00 66.69  ? 51  GLU A C     1 
ATOM   381  O  O     . GLU A 1 51  ? 3.503   -7.581  24.939  1.00 68.64  ? 51  GLU A O     1 
ATOM   382  C  CB    . GLU A 1 51  ? 5.302   -6.418  27.234  1.00 67.41  ? 51  GLU A CB    1 
ATOM   383  C  CG    . GLU A 1 51  ? 5.464   -6.687  28.737  1.00 70.29  ? 51  GLU A CG    1 
ATOM   384  C  CD    . GLU A 1 51  ? 5.433   -5.415  29.592  1.00 78.00  ? 51  GLU A CD    1 
ATOM   385  O  OE1   . GLU A 1 51  ? 4.693   -4.469  29.240  1.00 78.35  ? 51  GLU A OE1   1 
ATOM   386  O  OE2   . GLU A 1 51  ? 6.161   -5.357  30.610  1.00 78.87  ? 51  GLU A OE2   1 
ATOM   387  N  N     . ASP A 1 52  ? 5.462   -7.057  23.966  1.00 66.74  ? 52  ASP A N     1 
ATOM   388  C  CA    . ASP A 1 52  ? 4.879   -6.707  22.666  1.00 69.45  ? 52  ASP A CA    1 
ATOM   389  C  C     . ASP A 1 52  ? 4.969   -7.861  21.672  1.00 71.44  ? 52  ASP A C     1 
ATOM   390  O  O     . ASP A 1 52  ? 5.376   -7.677  20.522  1.00 72.13  ? 52  ASP A O     1 
ATOM   391  C  CB    . ASP A 1 52  ? 5.561   -5.462  22.108  1.00 64.24  ? 52  ASP A CB    1 
ATOM   392  C  CG    . ASP A 1 52  ? 7.061   -5.620  22.021  1.00 72.06  ? 52  ASP A CG    1 
ATOM   393  O  OD1   . ASP A 1 52  ? 7.652   -6.055  23.025  1.00 76.39  ? 52  ASP A OD1   1 
ATOM   394  O  OD2   . ASP A 1 52  ? 7.649   -5.332  20.956  1.00 73.06  ? 52  ASP A OD2   1 
ATOM   395  N  N     . VAL A 1 53  ? 4.572   -9.061  22.084  1.00 70.47  ? 53  VAL A N     1 
ATOM   396  C  CA    . VAL A 1 53  ? 4.599   -10.236 21.221  1.00 67.97  ? 53  VAL A CA    1 
ATOM   397  C  C     . VAL A 1 53  ? 3.214   -10.425 20.614  1.00 74.63  ? 53  VAL A C     1 
ATOM   398  O  O     . VAL A 1 53  ? 2.212   -10.496 21.337  1.00 76.67  ? 53  VAL A O     1 
ATOM   399  C  CB    . VAL A 1 53  ? 5.043   -11.483 22.003  1.00 60.55  ? 53  VAL A CB    1 
ATOM   400  C  CG1   . VAL A 1 53  ? 5.315   -12.635 21.058  1.00 64.28  ? 53  VAL A CG1   1 
ATOM   401  C  CG2   . VAL A 1 53  ? 6.275   -11.169 22.832  1.00 55.20  ? 53  VAL A CG2   1 
ATOM   402  N  N     . ASP A 1 54  ? 3.152   -10.491 19.284  1.00 68.22  ? 54  ASP A N     1 
ATOM   403  C  CA    . ASP A 1 54  ? 1.900   -10.721 18.568  1.00 72.73  ? 54  ASP A CA    1 
ATOM   404  C  C     . ASP A 1 54  ? 2.113   -11.816 17.532  1.00 74.38  ? 54  ASP A C     1 
ATOM   405  O  O     . ASP A 1 54  ? 2.934   -11.638 16.609  1.00 77.70  ? 54  ASP A O     1 
ATOM   406  C  CB    . ASP A 1 54  ? 1.382   -9.452  17.893  1.00 81.36  ? 54  ASP A CB    1 
ATOM   407  C  CG    . ASP A 1 54  ? -0.059  -9.592  17.440  1.00 94.61  ? 54  ASP A CG    1 
ATOM   408  O  OD1   . ASP A 1 54  ? -0.925  -9.879  18.294  1.00 93.01  ? 54  ASP A OD1   1 
ATOM   409  O  OD2   . ASP A 1 54  ? -0.319  -9.449  16.224  1.00 101.78 ? 54  ASP A OD2   1 
ATOM   410  N  N     . PRO A 1 55  ? 1.389   -12.942 17.610  1.00 71.67  ? 55  PRO A N     1 
ATOM   411  C  CA    . PRO A 1 55  ? 0.340   -13.276 18.582  1.00 67.89  ? 55  PRO A CA    1 
ATOM   412  C  C     . PRO A 1 55  ? 0.923   -13.538 19.957  1.00 69.63  ? 55  PRO A C     1 
ATOM   413  O  O     . PRO A 1 55  ? 1.933   -14.213 20.076  1.00 72.37  ? 55  PRO A O     1 
ATOM   414  C  CB    . PRO A 1 55  ? -0.286  -14.544 17.991  1.00 75.76  ? 55  PRO A CB    1 
ATOM   415  C  CG    . PRO A 1 55  ? 0.834   -15.186 17.240  1.00 65.52  ? 55  PRO A CG    1 
ATOM   416  C  CD    . PRO A 1 55  ? 1.604   -14.036 16.648  1.00 66.32  ? 55  PRO A CD    1 
ATOM   417  N  N     . PRO A 1 56  ? 0.294   -13.022 21.016  1.00 73.45  ? 56  PRO A N     1 
ATOM   418  C  CA    . PRO A 1 56  ? 0.818   -13.239 22.371  1.00 71.98  ? 56  PRO A CA    1 
ATOM   419  C  C     . PRO A 1 56  ? 0.813   -14.695 22.811  1.00 72.90  ? 56  PRO A C     1 
ATOM   420  O  O     . PRO A 1 56  ? 1.362   -15.003 23.875  1.00 71.09  ? 56  PRO A O     1 
ATOM   421  C  CB    . PRO A 1 56  ? -0.124  -12.400 23.248  1.00 75.75  ? 56  PRO A CB    1 
ATOM   422  C  CG    . PRO A 1 56  ? -0.781  -11.439 22.291  1.00 76.33  ? 56  PRO A CG    1 
ATOM   423  C  CD    . PRO A 1 56  ? -0.939  -12.225 21.031  1.00 76.44  ? 56  PRO A CD    1 
ATOM   424  N  N     . GLU A 1 57  ? 0.222   -15.602 22.034  1.00 75.33  ? 57  GLU A N     1 
ATOM   425  C  CA    . GLU A 1 57  ? 0.200   -17.012 22.404  1.00 82.48  ? 57  GLU A CA    1 
ATOM   426  C  C     . GLU A 1 57  ? 1.574   -17.673 22.325  1.00 79.53  ? 57  GLU A C     1 
ATOM   427  O  O     . GLU A 1 57  ? 1.744   -18.777 22.856  1.00 76.75  ? 57  GLU A O     1 
ATOM   428  C  CB    . GLU A 1 57  ? -0.791  -17.757 21.509  1.00 81.80  ? 57  GLU A CB    1 
ATOM   429  C  CG    . GLU A 1 57  ? -2.239  -17.348 21.725  1.00 86.11  ? 57  GLU A CG    1 
ATOM   430  C  CD    . GLU A 1 57  ? -2.976  -17.111 20.418  1.00 94.18  ? 57  GLU A CD    1 
ATOM   431  O  OE1   . GLU A 1 57  ? -2.341  -17.261 19.350  1.00 95.88  ? 57  GLU A OE1   1 
ATOM   432  O  OE2   . GLU A 1 57  ? -4.187  -16.796 20.458  1.00 90.35  ? 57  GLU A OE2   1 
ATOM   433  N  N     . ILE A 1 58  ? 2.554   -17.021 21.698  1.00 74.71  ? 58  ILE A N     1 
ATOM   434  C  CA    . ILE A 1 58  ? 3.864   -17.640 21.514  1.00 71.26  ? 58  ILE A CA    1 
ATOM   435  C  C     . ILE A 1 58  ? 4.592   -17.788 22.843  1.00 73.03  ? 58  ILE A C     1 
ATOM   436  O  O     . ILE A 1 58  ? 5.214   -18.824 23.112  1.00 69.73  ? 58  ILE A O     1 
ATOM   437  C  CB    . ILE A 1 58  ? 4.688   -16.830 20.500  1.00 63.90  ? 58  ILE A CB    1 
ATOM   438  C  CG1   . ILE A 1 58  ? 4.106   -17.014 19.102  1.00 65.12  ? 58  ILE A CG1   1 
ATOM   439  C  CG2   . ILE A 1 58  ? 6.153   -17.225 20.546  1.00 63.86  ? 58  ILE A CG2   1 
ATOM   440  C  CD1   . ILE A 1 58  ? 4.348   -15.856 18.193  1.00 66.43  ? 58  ILE A CD1   1 
ATOM   441  N  N     . VAL A 1 59  ? 4.527   -16.767 23.695  1.00 73.99  ? 59  VAL A N     1 
ATOM   442  C  CA    . VAL A 1 59  ? 5.233   -16.771 24.970  1.00 70.57  ? 59  VAL A CA    1 
ATOM   443  C  C     . VAL A 1 59  ? 4.291   -16.996 26.149  1.00 71.43  ? 59  VAL A C     1 
ATOM   444  O  O     . VAL A 1 59  ? 4.726   -16.924 27.302  1.00 73.64  ? 59  VAL A O     1 
ATOM   445  C  CB    . VAL A 1 59  ? 6.049   -15.480 25.155  1.00 63.82  ? 59  VAL A CB    1 
ATOM   446  C  CG1   . VAL A 1 59  ? 6.942   -15.245 23.951  1.00 67.11  ? 59  VAL A CG1   1 
ATOM   447  C  CG2   . VAL A 1 59  ? 5.128   -14.298 25.346  1.00 61.49  ? 59  VAL A CG2   1 
ATOM   448  N  N     . ALA A 1 60  ? 3.013   -17.302 25.892  1.00 72.41  ? 60  ALA A N     1 
ATOM   449  C  CA    . ALA A 1 60  ? 2.034   -17.399 26.974  1.00 70.87  ? 60  ALA A CA    1 
ATOM   450  C  C     . ALA A 1 60  ? 2.280   -18.605 27.875  1.00 70.08  ? 60  ALA A C     1 
ATOM   451  O  O     . ALA A 1 60  ? 1.982   -18.557 29.076  1.00 63.91  ? 60  ALA A O     1 
ATOM   452  C  CB    . ALA A 1 60  ? 0.624   -17.461 26.392  1.00 72.45  ? 60  ALA A CB    1 
ATOM   453  N  N     . HIS A 1 61  ? 2.798   -19.695 27.315  1.00 71.37  ? 61  HIS A N     1 
ATOM   454  C  CA    . HIS A 1 61  ? 3.082   -20.889 28.096  1.00 69.86  ? 61  HIS A CA    1 
ATOM   455  C  C     . HIS A 1 61  ? 4.209   -20.696 29.100  1.00 70.14  ? 61  HIS A C     1 
ATOM   456  O  O     . HIS A 1 61  ? 4.365   -21.536 29.991  1.00 71.12  ? 61  HIS A O     1 
ATOM   457  C  CB    . HIS A 1 61  ? 3.434   -22.033 27.157  1.00 67.73  ? 61  HIS A CB    1 
ATOM   458  C  CG    . HIS A 1 61  ? 4.549   -21.704 26.218  1.00 66.72  ? 61  HIS A CG    1 
ATOM   459  N  ND1   . HIS A 1 61  ? 5.868   -21.659 26.614  1.00 63.61  ? 61  HIS A ND1   1 
ATOM   460  C  CD2   . HIS A 1 61  ? 4.542   -21.411 24.896  1.00 72.71  ? 61  HIS A CD2   1 
ATOM   461  C  CE1   . HIS A 1 61  ? 6.626   -21.349 25.578  1.00 67.28  ? 61  HIS A CE1   1 
ATOM   462  N  NE2   . HIS A 1 61  ? 5.846   -21.192 24.523  1.00 72.86  ? 61  HIS A NE2   1 
ATOM   463  N  N     . LEU A 1 62  ? 4.979   -19.609 28.994  1.00 69.81  ? 62  LEU A N     1 
ATOM   464  C  CA    . LEU A 1 62  ? 6.207   -19.502 29.781  1.00 68.88  ? 62  LEU A CA    1 
ATOM   465  C  C     . LEU A 1 62  ? 5.955   -19.391 31.281  1.00 71.51  ? 62  LEU A C     1 
ATOM   466  O  O     . LEU A 1 62  ? 6.504   -20.215 32.036  1.00 71.79  ? 62  LEU A O     1 
ATOM   467  C  CB    . LEU A 1 62  ? 7.051   -18.338 29.259  1.00 66.51  ? 62  LEU A CB    1 
ATOM   468  C  CG    . LEU A 1 62  ? 7.891   -18.735 28.045  1.00 61.07  ? 62  LEU A CG    1 
ATOM   469  C  CD1   . LEU A 1 62  ? 8.581   -17.526 27.439  1.00 61.83  ? 62  LEU A CD1   1 
ATOM   470  C  CD2   . LEU A 1 62  ? 8.888   -19.808 28.422  1.00 58.55  ? 62  LEU A CD2   1 
ATOM   471  N  N     . PRO A 1 63  ? 5.159   -18.436 31.783  1.00 69.65  ? 63  PRO A N     1 
ATOM   472  C  CA    . PRO A 1 63  ? 5.079   -18.258 33.244  1.00 69.16  ? 63  PRO A CA    1 
ATOM   473  C  C     . PRO A 1 63  ? 4.665   -19.510 33.993  1.00 73.69  ? 63  PRO A C     1 
ATOM   474  O  O     . PRO A 1 63  ? 5.201   -19.781 35.074  1.00 78.05  ? 63  PRO A O     1 
ATOM   475  C  CB    . PRO A 1 63  ? 4.040   -17.139 33.401  1.00 74.52  ? 63  PRO A CB    1 
ATOM   476  C  CG    . PRO A 1 63  ? 4.044   -16.434 32.086  1.00 73.15  ? 63  PRO A CG    1 
ATOM   477  C  CD    . PRO A 1 63  ? 4.253   -17.512 31.082  1.00 69.39  ? 63  PRO A CD    1 
ATOM   478  N  N     . LEU A 1 64  ? 3.738   -20.296 33.442  1.00 76.80  ? 64  LEU A N     1 
ATOM   479  C  CA    . LEU A 1 64  ? 3.290   -21.495 34.146  1.00 83.41  ? 64  LEU A CA    1 
ATOM   480  C  C     . LEU A 1 64  ? 4.389   -22.554 34.192  1.00 81.87  ? 64  LEU A C     1 
ATOM   481  O  O     . LEU A 1 64  ? 4.553   -23.241 35.208  1.00 77.03  ? 64  LEU A O     1 
ATOM   482  C  CB    . LEU A 1 64  ? 2.031   -22.048 33.483  1.00 89.01  ? 64  LEU A CB    1 
ATOM   483  C  CG    . LEU A 1 64  ? 0.831   -21.110 33.631  1.00 88.34  ? 64  LEU A CG    1 
ATOM   484  C  CD1   . LEU A 1 64  ? -0.221  -21.428 32.575  1.00 88.16  ? 64  LEU A CD1   1 
ATOM   485  C  CD2   . LEU A 1 64  ? 0.256   -21.142 35.038  1.00 76.70  ? 64  LEU A CD2   1 
ATOM   486  N  N     . LEU A 1 65  ? 5.161   -22.690 33.109  1.00 77.38  ? 65  LEU A N     1 
ATOM   487  C  CA    . LEU A 1 65  ? 6.289   -23.617 33.125  1.00 72.34  ? 65  LEU A CA    1 
ATOM   488  C  C     . LEU A 1 65  ? 7.359   -23.170 34.114  1.00 75.90  ? 65  LEU A C     1 
ATOM   489  O  O     . LEU A 1 65  ? 7.941   -24.003 34.821  1.00 81.02  ? 65  LEU A O     1 
ATOM   490  C  CB    . LEU A 1 65  ? 6.874   -23.771 31.720  1.00 62.57  ? 65  LEU A CB    1 
ATOM   491  C  CG    . LEU A 1 65  ? 8.052   -24.744 31.565  1.00 71.62  ? 65  LEU A CG    1 
ATOM   492  C  CD1   . LEU A 1 65  ? 7.804   -26.074 32.273  1.00 84.17  ? 65  LEU A CD1   1 
ATOM   493  C  CD2   . LEU A 1 65  ? 8.403   -24.988 30.092  1.00 62.86  ? 65  LEU A CD2   1 
ATOM   494  N  N     . CYS A 1 66  ? 7.632   -21.862 34.186  1.00 76.04  ? 66  CYS A N     1 
ATOM   495  C  CA    . CYS A 1 66  ? 8.588   -21.378 35.179  1.00 72.80  ? 66  CYS A CA    1 
ATOM   496  C  C     . CYS A 1 66  ? 8.084   -21.610 36.594  1.00 74.44  ? 66  CYS A C     1 
ATOM   497  O  O     . CYS A 1 66  ? 8.876   -21.887 37.500  1.00 77.29  ? 66  CYS A O     1 
ATOM   498  C  CB    . CYS A 1 66  ? 8.890   -19.897 34.974  1.00 72.06  ? 66  CYS A CB    1 
ATOM   499  S  SG    . CYS A 1 66  ? 9.385   -19.438 33.326  1.00 79.50  ? 66  CYS A SG    1 
ATOM   500  N  N     . GLU A 1 67  ? 6.775   -21.484 36.814  1.00 74.49  ? 67  GLU A N     1 
ATOM   501  C  CA    . GLU A 1 67  ? 6.250   -21.810 38.133  1.00 82.14  ? 67  GLU A CA    1 
ATOM   502  C  C     . GLU A 1 67  ? 6.412   -23.296 38.418  1.00 81.00  ? 67  GLU A C     1 
ATOM   503  O  O     . GLU A 1 67  ? 6.763   -23.684 39.538  1.00 82.16  ? 67  GLU A O     1 
ATOM   504  C  CB    . GLU A 1 67  ? 4.785   -21.388 38.254  1.00 84.53  ? 67  GLU A CB    1 
ATOM   505  C  CG    . GLU A 1 67  ? 4.580   -19.904 38.528  1.00 75.95  ? 67  GLU A CG    1 
ATOM   506  C  CD    . GLU A 1 67  ? 3.245   -19.400 38.012  1.00 87.85  ? 67  GLU A CD    1 
ATOM   507  O  OE1   . GLU A 1 67  ? 2.705   -20.012 37.065  1.00 92.45  ? 67  GLU A OE1   1 
ATOM   508  O  OE2   . GLU A 1 67  ? 2.739   -18.388 38.547  1.00 90.79  ? 67  GLU A OE2   1 
ATOM   509  N  N     . GLU A 1 68  ? 6.195   -24.138 37.406  1.00 76.72  ? 68  GLU A N     1 
ATOM   510  C  CA    . GLU A 1 68  ? 6.390   -25.573 37.582  1.00 78.03  ? 68  GLU A CA    1 
ATOM   511  C  C     . GLU A 1 68  ? 7.826   -25.888 37.978  1.00 80.00  ? 68  GLU A C     1 
ATOM   512  O  O     . GLU A 1 68  ? 8.067   -26.670 38.903  1.00 85.09  ? 68  GLU A O     1 
ATOM   513  C  CB    . GLU A 1 68  ? 6.022   -26.323 36.304  1.00 79.74  ? 68  GLU A CB    1 
ATOM   514  C  CG    . GLU A 1 68  ? 4.537   -26.474 36.076  1.00 91.77  ? 68  GLU A CG    1 
ATOM   515  C  CD    . GLU A 1 68  ? 4.226   -27.455 34.961  1.00 103.14 ? 68  GLU A CD    1 
ATOM   516  O  OE1   . GLU A 1 68  ? 5.084   -28.329 34.690  1.00 102.78 ? 68  GLU A OE1   1 
ATOM   517  O  OE2   . GLU A 1 68  ? 3.132   -27.346 34.356  1.00 102.03 ? 68  GLU A OE2   1 
ATOM   518  N  N     . LYS A 1 69  ? 8.793   -25.290 37.286  1.00 75.83  ? 69  LYS A N     1 
ATOM   519  C  CA    . LYS A 1 69  ? 10.203  -25.577 37.516  1.00 74.55  ? 69  LYS A CA    1 
ATOM   520  C  C     . LYS A 1 69  ? 10.873  -24.603 38.482  1.00 77.02  ? 69  LYS A C     1 
ATOM   521  O  O     . LYS A 1 69  ? 12.091  -24.688 38.670  1.00 74.23  ? 69  LYS A O     1 
ATOM   522  C  CB    . LYS A 1 69  ? 10.960  -25.597 36.185  1.00 72.86  ? 69  LYS A CB    1 
ATOM   523  C  CG    . LYS A 1 69  ? 10.542  -26.726 35.273  1.00 75.75  ? 69  LYS A CG    1 
ATOM   524  C  CD    . LYS A 1 69  ? 10.945  -28.058 35.879  1.00 80.34  ? 69  LYS A CD    1 
ATOM   525  C  CE    . LYS A 1 69  ? 10.125  -29.205 35.312  1.00 91.54  ? 69  LYS A CE    1 
ATOM   526  N  NZ    . LYS A 1 69  ? 9.997   -30.339 36.281  1.00 87.12  ? 69  LYS A NZ    1 
ATOM   527  N  N     . ASN A 1 70  ? 10.108  -23.704 39.108  1.00 82.60  ? 70  ASN A N     1 
ATOM   528  C  CA    . ASN A 1 70  ? 10.633  -22.693 40.036  1.00 84.96  ? 70  ASN A CA    1 
ATOM   529  C  C     . ASN A 1 70  ? 11.742  -21.854 39.402  1.00 78.14  ? 70  ASN A C     1 
ATOM   530  O  O     . ASN A 1 70  ? 12.860  -21.749 39.907  1.00 78.74  ? 70  ASN A O     1 
ATOM   531  C  CB    . ASN A 1 70  ? 11.108  -23.331 41.345  1.00 78.83  ? 70  ASN A CB    1 
ATOM   532  C  CG    . ASN A 1 70  ? 9.978   -23.969 42.113  1.00 94.90  ? 70  ASN A CG    1 
ATOM   533  O  OD1   . ASN A 1 70  ? 8.945   -23.336 42.338  1.00 100.06 ? 70  ASN A OD1   1 
ATOM   534  N  ND2   . ASN A 1 70  ? 10.154  -25.224 42.511  1.00 108.17 ? 70  ASN A ND2   1 
ATOM   535  N  N     . VAL A 1 71  ? 11.394  -21.215 38.284  1.00 71.54  ? 71  VAL A N     1 
ATOM   536  C  CA    . VAL A 1 71  ? 12.294  -20.331 37.564  1.00 67.32  ? 71  VAL A CA    1 
ATOM   537  C  C     . VAL A 1 71  ? 11.706  -18.930 37.612  1.00 68.17  ? 71  VAL A C     1 
ATOM   538  O  O     . VAL A 1 71  ? 10.540  -18.746 37.260  1.00 72.44  ? 71  VAL A O     1 
ATOM   539  C  CB    . VAL A 1 71  ? 12.503  -20.774 36.103  1.00 73.26  ? 71  VAL A CB    1 
ATOM   540  C  CG1   . VAL A 1 71  ? 13.232  -19.688 35.326  1.00 67.16  ? 71  VAL A CG1   1 
ATOM   541  C  CG2   . VAL A 1 71  ? 13.256  -22.100 36.059  1.00 72.52  ? 71  VAL A CG2   1 
ATOM   542  N  N     . PRO A 1 72  ? 12.457  -17.925 38.055  1.00 62.36  ? 72  PRO A N     1 
ATOM   543  C  CA    . PRO A 1 72  ? 11.926  -16.556 38.072  1.00 66.18  ? 72  PRO A CA    1 
ATOM   544  C  C     . PRO A 1 72  ? 11.841  -15.977 36.663  1.00 66.53  ? 72  PRO A C     1 
ATOM   545  O  O     . PRO A 1 72  ? 12.801  -16.038 35.887  1.00 70.10  ? 72  PRO A O     1 
ATOM   546  C  CB    . PRO A 1 72  ? 12.937  -15.796 38.938  1.00 62.29  ? 72  PRO A CB    1 
ATOM   547  C  CG    . PRO A 1 72  ? 14.190  -16.620 38.869  1.00 61.40  ? 72  PRO A CG    1 
ATOM   548  C  CD    . PRO A 1 72  ? 13.737  -18.040 38.768  1.00 61.48  ? 72  PRO A CD    1 
ATOM   549  N  N     . TYR A 1 73  ? 10.676  -15.422 36.336  1.00 60.84  ? 73  TYR A N     1 
ATOM   550  C  CA    . TYR A 1 73  ? 10.448  -14.761 35.061  1.00 63.05  ? 73  TYR A CA    1 
ATOM   551  C  C     . TYR A 1 73  ? 10.173  -13.285 35.299  1.00 66.41  ? 73  TYR A C     1 
ATOM   552  O  O     . TYR A 1 73  ? 9.643   -12.893 36.341  1.00 69.64  ? 73  TYR A O     1 
ATOM   553  C  CB    . TYR A 1 73  ? 9.286   -15.406 34.278  1.00 58.69  ? 73  TYR A CB    1 
ATOM   554  C  CG    . TYR A 1 73  ? 7.995   -15.570 35.039  1.00 65.76  ? 73  TYR A CG    1 
ATOM   555  C  CD1   . TYR A 1 73  ? 7.840   -16.590 35.959  1.00 73.49  ? 73  TYR A CD1   1 
ATOM   556  C  CD2   . TYR A 1 73  ? 6.910   -14.742 34.794  1.00 69.68  ? 73  TYR A CD2   1 
ATOM   557  C  CE1   . TYR A 1 73  ? 6.661   -16.757 36.651  1.00 79.19  ? 73  TYR A CE1   1 
ATOM   558  C  CE2   . TYR A 1 73  ? 5.719   -14.905 35.480  1.00 76.37  ? 73  TYR A CE2   1 
ATOM   559  C  CZ    . TYR A 1 73  ? 5.600   -15.918 36.409  1.00 76.63  ? 73  TYR A CZ    1 
ATOM   560  O  OH    . TYR A 1 73  ? 4.421   -16.100 37.102  1.00 75.09  ? 73  TYR A OH    1 
ATOM   561  N  N     . ILE A 1 74  ? 10.562  -12.466 34.330  1.00 62.42  ? 74  ILE A N     1 
ATOM   562  C  CA    . ILE A 1 74  ? 10.361  -11.027 34.410  1.00 57.17  ? 74  ILE A CA    1 
ATOM   563  C  C     . ILE A 1 74  ? 9.928   -10.531 33.040  1.00 61.44  ? 74  ILE A C     1 
ATOM   564  O  O     . ILE A 1 74  ? 10.436  -10.993 32.015  1.00 63.03  ? 74  ILE A O     1 
ATOM   565  C  CB    . ILE A 1 74  ? 11.635  -10.305 34.889  1.00 55.55  ? 74  ILE A CB    1 
ATOM   566  C  CG1   . ILE A 1 74  ? 11.413  -8.795  34.918  1.00 61.60  ? 74  ILE A CG1   1 
ATOM   567  C  CG2   . ILE A 1 74  ? 12.820  -10.658 34.002  1.00 53.17  ? 74  ILE A CG2   1 
ATOM   568  C  CD1   . ILE A 1 74  ? 12.064  -8.104  36.109  1.00 66.58  ? 74  ILE A CD1   1 
ATOM   569  N  N     . TYR A 1 75  ? 8.980   -9.601  33.022  1.00 66.66  ? 75  TYR A N     1 
ATOM   570  C  CA    . TYR A 1 75  ? 8.473   -9.036  31.781  1.00 65.84  ? 75  TYR A CA    1 
ATOM   571  C  C     . TYR A 1 75  ? 9.241   -7.767  31.437  1.00 62.85  ? 75  TYR A C     1 
ATOM   572  O  O     . TYR A 1 75  ? 9.365   -6.866  32.270  1.00 66.91  ? 75  TYR A O     1 
ATOM   573  C  CB    . TYR A 1 75  ? 6.981   -8.727  31.899  1.00 70.59  ? 75  TYR A CB    1 
ATOM   574  C  CG    . TYR A 1 75  ? 6.091   -9.944  32.009  1.00 70.90  ? 75  TYR A CG    1 
ATOM   575  C  CD1   . TYR A 1 75  ? 5.681   -10.623 30.872  1.00 69.24  ? 75  TYR A CD1   1 
ATOM   576  C  CD2   . TYR A 1 75  ? 5.637   -10.395 33.240  1.00 71.85  ? 75  TYR A CD2   1 
ATOM   577  C  CE1   . TYR A 1 75  ? 4.859   -11.725 30.953  1.00 74.16  ? 75  TYR A CE1   1 
ATOM   578  C  CE2   . TYR A 1 75  ? 4.813   -11.502 33.332  1.00 75.08  ? 75  TYR A CE2   1 
ATOM   579  C  CZ    . TYR A 1 75  ? 4.428   -12.163 32.182  1.00 79.16  ? 75  TYR A CZ    1 
ATOM   580  O  OH    . TYR A 1 75  ? 3.608   -13.265 32.252  1.00 86.28  ? 75  TYR A OH    1 
ATOM   581  N  N     . VAL A 1 76  ? 9.752   -7.703  30.211  1.00 61.98  ? 76  VAL A N     1 
ATOM   582  C  CA    . VAL A 1 76  ? 10.412  -6.515  29.689  1.00 63.78  ? 76  VAL A CA    1 
ATOM   583  C  C     . VAL A 1 76  ? 9.514   -5.865  28.641  1.00 66.71  ? 76  VAL A C     1 
ATOM   584  O  O     . VAL A 1 76  ? 8.641   -6.501  28.043  1.00 64.16  ? 76  VAL A O     1 
ATOM   585  C  CB    . VAL A 1 76  ? 11.802  -6.837  29.105  1.00 60.20  ? 76  VAL A CB    1 
ATOM   586  C  CG1   . VAL A 1 76  ? 12.770  -7.165  30.221  1.00 59.02  ? 76  VAL A CG1   1 
ATOM   587  C  CG2   . VAL A 1 76  ? 11.713  -7.991  28.121  1.00 61.43  ? 76  VAL A CG2   1 
ATOM   588  N  N     . LYS A 1 77  ? 9.749   -4.570  28.416  1.00 67.59  ? 77  LYS A N     1 
ATOM   589  C  CA    . LYS A 1 77  ? 8.858   -3.778  27.573  1.00 65.85  ? 77  LYS A CA    1 
ATOM   590  C  C     . LYS A 1 77  ? 8.855   -4.282  26.135  1.00 70.45  ? 77  LYS A C     1 
ATOM   591  O  O     . LYS A 1 77  ? 7.814   -4.694  25.614  1.00 74.75  ? 77  LYS A O     1 
ATOM   592  C  CB    . LYS A 1 77  ? 9.252   -2.301  27.625  1.00 63.83  ? 77  LYS A CB    1 
ATOM   593  C  CG    . LYS A 1 77  ? 9.964   -1.904  28.897  1.00 75.12  ? 77  LYS A CG    1 
ATOM   594  C  CD    . LYS A 1 77  ? 9.838   -0.415  29.165  1.00 84.42  ? 77  LYS A CD    1 
ATOM   595  C  CE    . LYS A 1 77  ? 10.597  -0.041  30.428  1.00 91.13  ? 77  LYS A CE    1 
ATOM   596  N  NZ    . LYS A 1 77  ? 12.063  -0.321  30.283  1.00 84.81  ? 77  LYS A NZ    1 
ATOM   597  N  N     . SER A 1 78  ? 10.005  -4.256  25.470  1.00 75.30  ? 78  SER A N     1 
ATOM   598  C  CA    . SER A 1 78  ? 10.059  -4.603  24.058  1.00 71.34  ? 78  SER A CA    1 
ATOM   599  C  C     . SER A 1 78  ? 10.964  -5.804  23.816  1.00 73.10  ? 78  SER A C     1 
ATOM   600  O  O     . SER A 1 78  ? 11.909  -6.065  24.572  1.00 70.39  ? 78  SER A O     1 
ATOM   601  C  CB    . SER A 1 78  ? 10.544  -3.429  23.205  1.00 74.88  ? 78  SER A CB    1 
ATOM   602  O  OG    . SER A 1 78  ? 11.002  -3.896  21.946  1.00 78.95  ? 78  SER A OG    1 
ATOM   603  N  N     . LYS A 1 79  ? 10.656  -6.532  22.738  1.00 69.50  ? 79  LYS A N     1 
ATOM   604  C  CA    . LYS A 1 79  ? 11.524  -7.618  22.298  1.00 66.89  ? 79  LYS A CA    1 
ATOM   605  C  C     . LYS A 1 79  ? 12.828  -7.087  21.717  1.00 64.85  ? 79  LYS A C     1 
ATOM   606  O  O     . LYS A 1 79  ? 13.836  -7.803  21.702  1.00 62.85  ? 79  LYS A O     1 
ATOM   607  C  CB    . LYS A 1 79  ? 10.807  -8.477  21.261  1.00 63.49  ? 79  LYS A CB    1 
ATOM   608  C  CG    . LYS A 1 79  ? 10.276  -7.678  20.087  1.00 68.37  ? 79  LYS A CG    1 
ATOM   609  C  CD    . LYS A 1 79  ? 10.192  -8.534  18.844  1.00 60.97  ? 79  LYS A CD    1 
ATOM   610  C  CE    . LYS A 1 79  ? 8.928   -9.348  18.861  1.00 61.81  ? 79  LYS A CE    1 
ATOM   611  N  NZ    . LYS A 1 79  ? 7.748   -8.451  18.837  1.00 77.44  ? 79  LYS A NZ    1 
ATOM   612  N  N     . ASN A 1 80  ? 12.821  -5.848  21.214  1.00 65.57  ? 80  ASN A N     1 
ATOM   613  C  CA    . ASN A 1 80  ? 14.063  -5.213  20.786  1.00 73.72  ? 80  ASN A CA    1 
ATOM   614  C  C     . ASN A 1 80  ? 14.987  -4.954  21.968  1.00 72.48  ? 80  ASN A C     1 
ATOM   615  O  O     . ASN A 1 80  ? 16.214  -5.027  21.826  1.00 70.02  ? 80  ASN A O     1 
ATOM   616  C  CB    . ASN A 1 80  ? 13.760  -3.910  20.048  1.00 74.76  ? 80  ASN A CB    1 
ATOM   617  C  CG    . ASN A 1 80  ? 13.172  -4.145  18.667  1.00 84.80  ? 80  ASN A CG    1 
ATOM   618  O  OD1   . ASN A 1 80  ? 13.863  -4.601  17.752  1.00 86.53  ? 80  ASN A OD1   1 
ATOM   619  N  ND2   . ASN A 1 80  ? 11.885  -3.848  18.515  1.00 84.76  ? 80  ASN A ND2   1 
ATOM   620  N  N     . ASP A 1 81  ? 14.418  -4.658  23.140  1.00 72.95  ? 81  ASP A N     1 
ATOM   621  C  CA    . ASP A 1 81  ? 15.205  -4.568  24.362  1.00 73.13  ? 81  ASP A CA    1 
ATOM   622  C  C     . ASP A 1 81  ? 15.804  -5.908  24.748  1.00 67.78  ? 81  ASP A C     1 
ATOM   623  O  O     . ASP A 1 81  ? 16.695  -5.961  25.603  1.00 64.79  ? 81  ASP A O     1 
ATOM   624  C  CB    . ASP A 1 81  ? 14.341  -4.045  25.510  1.00 77.50  ? 81  ASP A CB    1 
ATOM   625  C  CG    . ASP A 1 81  ? 13.980  -2.586  25.346  1.00 90.91  ? 81  ASP A CG    1 
ATOM   626  O  OD1   . ASP A 1 81  ? 14.605  -1.919  24.488  1.00 95.57  ? 81  ASP A OD1   1 
ATOM   627  O  OD2   . ASP A 1 81  ? 13.080  -2.109  26.075  1.00 91.74  ? 81  ASP A OD2   1 
ATOM   628  N  N     . LEU A 1 82  ? 15.319  -6.988  24.150  1.00 68.10  ? 82  LEU A N     1 
ATOM   629  C  CA    . LEU A 1 82  ? 15.849  -8.317  24.383  1.00 67.12  ? 82  LEU A CA    1 
ATOM   630  C  C     . LEU A 1 82  ? 16.767  -8.763  23.258  1.00 62.28  ? 82  LEU A C     1 
ATOM   631  O  O     . LEU A 1 82  ? 17.333  -9.860  23.329  1.00 63.84  ? 82  LEU A O     1 
ATOM   632  C  CB    . LEU A 1 82  ? 14.700  -9.306  24.546  1.00 59.51  ? 82  LEU A CB    1 
ATOM   633  C  CG    . LEU A 1 82  ? 14.820  -10.265 25.717  1.00 54.05  ? 82  LEU A CG    1 
ATOM   634  C  CD1   . LEU A 1 82  ? 15.353  -9.533  26.931  1.00 57.27  ? 82  LEU A CD1   1 
ATOM   635  C  CD2   . LEU A 1 82  ? 13.448  -10.813 25.989  1.00 54.42  ? 82  LEU A CD2   1 
ATOM   636  N  N     . GLY A 1 83  ? 16.936  -7.929  22.228  1.00 60.65  ? 83  GLY A N     1 
ATOM   637  C  CA    . GLY A 1 83  ? 17.714  -8.328  21.069  1.00 64.76  ? 83  GLY A CA    1 
ATOM   638  C  C     . GLY A 1 83  ? 19.209  -8.335  21.303  1.00 66.22  ? 83  GLY A C     1 
ATOM   639  O  O     . GLY A 1 83  ? 19.943  -9.039  20.605  1.00 58.68  ? 83  GLY A O     1 
ATOM   640  N  N     . ARG A 1 84  ? 19.684  -7.562  22.278  1.00 69.22  ? 84  ARG A N     1 
ATOM   641  C  CA    . ARG A 1 84  ? 21.097  -7.502  22.620  1.00 66.82  ? 84  ARG A CA    1 
ATOM   642  C  C     . ARG A 1 84  ? 21.504  -8.582  23.605  1.00 63.98  ? 84  ARG A C     1 
ATOM   643  O  O     . ARG A 1 84  ? 22.561  -8.462  24.231  1.00 66.34  ? 84  ARG A O     1 
ATOM   644  C  CB    . ARG A 1 84  ? 21.430  -6.125  23.191  1.00 73.66  ? 84  ARG A CB    1 
ATOM   645  C  CG    . ARG A 1 84  ? 22.012  -5.157  22.187  1.00 69.47  ? 84  ARG A CG    1 
ATOM   646  C  CD    . ARG A 1 84  ? 22.058  -3.762  22.771  1.00 73.12  ? 84  ARG A CD    1 
ATOM   647  N  NE    . ARG A 1 84  ? 23.298  -3.506  23.494  1.00 82.82  ? 84  ARG A NE    1 
ATOM   648  C  CZ    . ARG A 1 84  ? 24.485  -3.342  22.924  1.00 91.80  ? 84  ARG A CZ    1 
ATOM   649  N  NH1   . ARG A 1 84  ? 24.637  -3.405  21.611  1.00 94.67  ? 84  ARG A NH1   1 
ATOM   650  N  NH2   . ARG A 1 84  ? 25.545  -3.094  23.691  1.00 89.42  ? 84  ARG A NH2   1 
ATOM   651  N  N     . ALA A 1 85  ? 20.692  -9.631  23.754  1.00 62.79  ? 85  ALA A N     1 
ATOM   652  C  CA    . ALA A 1 85  ? 20.941  -10.626 24.793  1.00 66.84  ? 85  ALA A CA    1 
ATOM   653  C  C     . ALA A 1 85  ? 22.274  -11.338 24.578  1.00 67.93  ? 85  ALA A C     1 
ATOM   654  O  O     . ALA A 1 85  ? 23.105  -11.399 25.490  1.00 65.84  ? 85  ALA A O     1 
ATOM   655  C  CB    . ALA A 1 85  ? 19.786  -11.628 24.845  1.00 63.14  ? 85  ALA A CB    1 
ATOM   656  N  N     . VAL A 1 86  ? 22.498  -11.880 23.380  1.00 67.41  ? 86  VAL A N     1 
ATOM   657  C  CA    . VAL A 1 86  ? 23.742  -12.581 23.075  1.00 63.96  ? 86  VAL A CA    1 
ATOM   658  C  C     . VAL A 1 86  ? 23.860  -12.718 21.566  1.00 67.23  ? 86  VAL A C     1 
ATOM   659  O  O     . VAL A 1 86  ? 22.856  -12.805 20.851  1.00 67.73  ? 86  VAL A O     1 
ATOM   660  C  CB    . VAL A 1 86  ? 23.805  -13.963 23.775  1.00 56.60  ? 86  VAL A CB    1 
ATOM   661  C  CG1   . VAL A 1 86  ? 23.022  -14.997 22.989  1.00 58.91  ? 86  VAL A CG1   1 
ATOM   662  C  CG2   . VAL A 1 86  ? 25.246  -14.397 23.961  1.00 61.31  ? 86  VAL A CG2   1 
ATOM   663  N  N     . GLY A 1 87  ? 25.101  -12.719 21.080  1.00 58.10  ? 87  GLY A N     1 
ATOM   664  C  CA    . GLY A 1 87  ? 25.344  -12.967 19.669  1.00 62.19  ? 87  GLY A CA    1 
ATOM   665  C  C     . GLY A 1 87  ? 24.769  -11.871 18.793  1.00 64.03  ? 87  GLY A C     1 
ATOM   666  O  O     . GLY A 1 87  ? 24.719  -10.695 19.169  1.00 61.90  ? 87  GLY A O     1 
ATOM   667  N  N     . ARG A 1 88  ? 24.326  -12.273 17.602  1.00 65.87  ? 88  ARG A N     1 
ATOM   668  C  CA    . ARG A 1 88  ? 23.804  -11.342 16.608  1.00 64.33  ? 88  ARG A CA    1 
ATOM   669  C  C     . ARG A 1 88  ? 22.690  -10.477 17.185  1.00 65.35  ? 88  ARG A C     1 
ATOM   670  O  O     . ARG A 1 88  ? 21.871  -10.941 17.981  1.00 68.04  ? 88  ARG A O     1 
ATOM   671  C  CB    . ARG A 1 88  ? 23.290  -12.128 15.401  1.00 56.55  ? 88  ARG A CB    1 
ATOM   672  C  CG    . ARG A 1 88  ? 22.715  -11.301 14.266  1.00 55.75  ? 88  ARG A CG    1 
ATOM   673  C  CD    . ARG A 1 88  ? 22.209  -12.237 13.180  1.00 51.97  ? 88  ARG A CD    1 
ATOM   674  N  NE    . ARG A 1 88  ? 21.414  -11.563 12.163  1.00 57.77  ? 88  ARG A NE    1 
ATOM   675  C  CZ    . ARG A 1 88  ? 20.384  -12.114 11.537  1.00 56.99  ? 88  ARG A CZ    1 
ATOM   676  N  NH1   . ARG A 1 88  ? 19.981  -13.338 11.823  1.00 58.40  ? 88  ARG A NH1   1 
ATOM   677  N  NH2   . ARG A 1 88  ? 19.756  -11.424 10.590  1.00 62.70  ? 88  ARG A NH2   1 
ATOM   678  N  N     . VAL A 1 89  ? 22.672  -9.204  16.795  1.00 63.46  ? 89  VAL A N     1 
ATOM   679  C  CA    . VAL A 1 89  ? 21.594  -8.311  17.212  1.00 63.63  ? 89  VAL A CA    1 
ATOM   680  C  C     . VAL A 1 89  ? 20.349  -8.676  16.412  1.00 64.49  ? 89  VAL A C     1 
ATOM   681  O  O     . VAL A 1 89  ? 20.303  -8.480  15.194  1.00 75.36  ? 89  VAL A O     1 
ATOM   682  C  CB    . VAL A 1 89  ? 21.968  -6.834  17.032  1.00 65.16  ? 89  VAL A CB    1 
ATOM   683  C  CG1   . VAL A 1 89  ? 22.887  -6.379  18.143  1.00 64.61  ? 89  VAL A CG1   1 
ATOM   684  C  CG2   . VAL A 1 89  ? 22.643  -6.599  15.672  1.00 75.69  ? 89  VAL A CG2   1 
ATOM   685  N  N     . TYR A 1 90  ? 19.340  -9.225  17.099  1.00 58.71  ? 90  TYR A N     1 
ATOM   686  C  CA    . TYR A 1 90  ? 18.099  -9.625  16.458  1.00 57.75  ? 90  TYR A CA    1 
ATOM   687  C  C     . TYR A 1 90  ? 17.015  -9.615  17.520  1.00 58.25  ? 90  TYR A C     1 
ATOM   688  O  O     . TYR A 1 90  ? 17.298  -10.001 18.661  1.00 61.33  ? 90  TYR A O     1 
ATOM   689  C  CB    . TYR A 1 90  ? 18.217  -11.021 15.833  1.00 55.41  ? 90  TYR A CB    1 
ATOM   690  C  CG    . TYR A 1 90  ? 17.227  -11.299 14.733  1.00 50.58  ? 90  TYR A CG    1 
ATOM   691  C  CD1   . TYR A 1 90  ? 17.521  -10.994 13.420  1.00 49.73  ? 90  TYR A CD1   1 
ATOM   692  C  CD2   . TYR A 1 90  ? 15.990  -11.849 15.015  1.00 57.99  ? 90  TYR A CD2   1 
ATOM   693  C  CE1   . TYR A 1 90  ? 16.614  -11.242 12.415  1.00 54.87  ? 90  TYR A CE1   1 
ATOM   694  C  CE2   . TYR A 1 90  ? 15.074  -12.097 14.017  1.00 63.07  ? 90  TYR A CE2   1 
ATOM   695  C  CZ    . TYR A 1 90  ? 15.391  -11.791 12.716  1.00 61.60  ? 90  TYR A CZ    1 
ATOM   696  O  OH    . TYR A 1 90  ? 14.474  -12.040 11.718  1.00 71.26  ? 90  TYR A OH    1 
ATOM   697  N  N     . PRO A 1 91  ? 15.786  -9.208  17.195  1.00 53.11  ? 91  PRO A N     1 
ATOM   698  C  CA    . PRO A 1 91  ? 14.725  -9.185  18.208  1.00 51.60  ? 91  PRO A CA    1 
ATOM   699  C  C     . PRO A 1 91  ? 14.570  -10.541 18.880  1.00 57.20  ? 91  PRO A C     1 
ATOM   700  O  O     . PRO A 1 91  ? 14.824  -11.583 18.274  1.00 63.93  ? 91  PRO A O     1 
ATOM   701  C  CB    . PRO A 1 91  ? 13.480  -8.839  17.387  1.00 55.39  ? 91  PRO A CB    1 
ATOM   702  C  CG    . PRO A 1 91  ? 14.003  -7.976  16.318  1.00 52.25  ? 91  PRO A CG    1 
ATOM   703  C  CD    . PRO A 1 91  ? 15.318  -8.617  15.928  1.00 54.33  ? 91  PRO A CD    1 
ATOM   704  N  N     . GLY A 1 92  ? 14.135  -10.527 20.137  1.00 57.98  ? 92  GLY A N     1 
ATOM   705  C  CA    . GLY A 1 92  ? 13.837  -11.775 20.813  1.00 57.54  ? 92  GLY A CA    1 
ATOM   706  C  C     . GLY A 1 92  ? 12.568  -11.739 21.643  1.00 59.81  ? 92  GLY A C     1 
ATOM   707  O  O     . GLY A 1 92  ? 12.452  -10.932 22.569  1.00 64.92  ? 92  GLY A O     1 
ATOM   708  N  N     . ALA A 1 93  ? 11.611  -12.620 21.332  1.00 53.54  ? 93  ALA A N     1 
ATOM   709  C  CA    . ALA A 1 93  ? 10.381  -12.701 22.115  1.00 49.78  ? 93  ALA A CA    1 
ATOM   710  C  C     . ALA A 1 93  ? 10.643  -13.093 23.562  1.00 53.46  ? 93  ALA A C     1 
ATOM   711  O  O     . ALA A 1 93  ? 9.846   -12.756 24.445  1.00 57.96  ? 93  ALA A O     1 
ATOM   712  C  CB    . ALA A 1 93  ? 9.413   -13.698 21.487  1.00 52.11  ? 93  ALA A CB    1 
ATOM   713  N  N     . SER A 1 94  ? 11.744  -13.785 23.825  1.00 52.99  ? 94  SER A N     1 
ATOM   714  C  CA    . SER A 1 94  ? 12.062  -14.242 25.167  1.00 52.37  ? 94  SER A CA    1 
ATOM   715  C  C     . SER A 1 94  ? 13.546  -14.551 25.223  1.00 55.33  ? 94  SER A C     1 
ATOM   716  O  O     . SER A 1 94  ? 14.171  -14.869 24.208  1.00 55.32  ? 94  SER A O     1 
ATOM   717  C  CB    . SER A 1 94  ? 11.238  -15.478 25.544  1.00 59.84  ? 94  SER A CB    1 
ATOM   718  O  OG    . SER A 1 94  ? 11.319  -16.469 24.530  1.00 58.12  ? 94  SER A OG    1 
ATOM   719  N  N     . ALA A 1 95  ? 14.097  -14.476 26.428  1.00 50.27  ? 95  ALA A N     1 
ATOM   720  C  CA    . ALA A 1 95  ? 15.487  -14.837 26.645  1.00 52.28  ? 95  ALA A CA    1 
ATOM   721  C  C     . ALA A 1 95  ? 15.602  -15.544 27.985  1.00 59.04  ? 95  ALA A C     1 
ATOM   722  O  O     . ALA A 1 95  ? 14.645  -15.608 28.758  1.00 62.44  ? 95  ALA A O     1 
ATOM   723  C  CB    . ALA A 1 95  ? 16.393  -13.608 26.589  1.00 52.21  ? 95  ALA A CB    1 
ATOM   724  N  N     . ALA A 1 96  ? 16.798  -16.051 28.271  1.00 58.06  ? 96  ALA A N     1 
ATOM   725  C  CA    . ALA A 1 96  ? 17.021  -16.720 29.550  1.00 59.74  ? 96  ALA A CA    1 
ATOM   726  C  C     . ALA A 1 96  ? 18.497  -16.675 29.910  1.00 65.94  ? 96  ALA A C     1 
ATOM   727  O  O     . ALA A 1 96  ? 19.344  -17.097 29.115  1.00 60.97  ? 96  ALA A O     1 
ATOM   728  C  CB    . ALA A 1 96  ? 16.530  -18.160 29.496  1.00 59.23  ? 96  ALA A CB    1 
ATOM   729  N  N     . ILE A 1 97  ? 18.801  -16.165 31.102  1.00 63.35  ? 97  ILE A N     1 
ATOM   730  C  CA    . ILE A 1 97  ? 20.128  -16.295 31.693  1.00 60.21  ? 97  ILE A CA    1 
ATOM   731  C  C     . ILE A 1 97  ? 20.242  -17.680 32.311  1.00 68.97  ? 97  ILE A C     1 
ATOM   732  O  O     . ILE A 1 97  ? 19.457  -18.039 33.202  1.00 68.21  ? 97  ILE A O     1 
ATOM   733  C  CB    . ILE A 1 97  ? 20.385  -15.209 32.745  1.00 61.60  ? 97  ILE A CB    1 
ATOM   734  C  CG1   . ILE A 1 97  ? 20.446  -13.829 32.083  1.00 70.40  ? 97  ILE A CG1   1 
ATOM   735  C  CG2   . ILE A 1 97  ? 21.652  -15.524 33.532  1.00 61.28  ? 97  ILE A CG2   1 
ATOM   736  C  CD1   . ILE A 1 97  ? 20.370  -12.678 33.066  1.00 69.80  ? 97  ILE A CD1   1 
ATOM   737  N  N     . ILE A 1 98  ? 21.225  -18.452 31.838  1.00 67.80  ? 98  ILE A N     1 
ATOM   738  C  CA    . ILE A 1 98  ? 21.424  -19.839 32.222  1.00 62.45  ? 98  ILE A CA    1 
ATOM   739  C  C     . ILE A 1 98  ? 22.491  -19.903 33.307  1.00 69.53  ? 98  ILE A C     1 
ATOM   740  O  O     . ILE A 1 98  ? 22.396  -20.707 34.240  1.00 73.39  ? 98  ILE A O     1 
ATOM   741  C  CB    . ILE A 1 98  ? 21.802  -20.678 30.991  1.00 63.83  ? 98  ILE A CB    1 
ATOM   742  C  CG1   . ILE A 1 98  ? 20.534  -21.043 30.218  1.00 66.50  ? 98  ILE A CG1   1 
ATOM   743  C  CG2   . ILE A 1 98  ? 22.554  -21.938 31.398  1.00 72.79  ? 98  ILE A CG2   1 
ATOM   744  C  CD1   . ILE A 1 98  ? 20.774  -21.923 29.025  1.00 69.56  ? 98  ILE A CD1   1 
ATOM   745  N  N     . ASN A 1 99  ? 23.510  -19.051 33.204  1.00 68.87  ? 99  ASN A N     1 
ATOM   746  C  CA    . ASN A 1 99  ? 24.476  -18.888 34.282  1.00 69.45  ? 99  ASN A CA    1 
ATOM   747  C  C     . ASN A 1 99  ? 24.606  -17.420 34.651  1.00 73.62  ? 99  ASN A C     1 
ATOM   748  O  O     . ASN A 1 99  ? 24.836  -16.569 33.784  1.00 65.17  ? 99  ASN A O     1 
ATOM   749  C  CB    . ASN A 1 99  ? 25.855  -19.440 33.928  1.00 71.92  ? 99  ASN A CB    1 
ATOM   750  C  CG    . ASN A 1 99  ? 26.681  -19.736 35.166  1.00 73.99  ? 99  ASN A CG    1 
ATOM   751  O  OD1   . ASN A 1 99  ? 26.322  -19.328 36.271  1.00 74.00  ? 99  ASN A OD1   1 
ATOM   752  N  ND2   . ASN A 1 99  ? 27.787  -20.441 34.990  1.00 72.81  ? 99  ASN A ND2   1 
ATOM   753  N  N     . GLU A 1 100 ? 24.478  -17.145 35.949  1.00 80.41  ? 100 GLU A N     1 
ATOM   754  C  CA    . GLU A 1 100 ? 24.660  -15.797 36.473  1.00 74.98  ? 100 GLU A CA    1 
ATOM   755  C  C     . GLU A 1 100 ? 26.073  -15.278 36.245  1.00 77.24  ? 100 GLU A C     1 
ATOM   756  O  O     . GLU A 1 100 ? 26.263  -14.071 36.068  1.00 80.17  ? 100 GLU A O     1 
ATOM   757  C  CB    . GLU A 1 100 ? 24.308  -15.797 37.956  1.00 71.51  ? 100 GLU A CB    1 
ATOM   758  C  CG    . GLU A 1 100 ? 24.577  -17.147 38.602  1.00 79.45  ? 100 GLU A CG    1 
ATOM   759  C  CD    . GLU A 1 100 ? 24.367  -17.141 40.099  1.00 96.44  ? 100 GLU A CD    1 
ATOM   760  O  OE1   . GLU A 1 100 ? 23.746  -16.181 40.605  1.00 101.08 ? 100 GLU A OE1   1 
ATOM   761  O  OE2   . GLU A 1 100 ? 24.805  -18.106 40.766  1.00 99.58  ? 100 GLU A OE2   1 
ATOM   762  N  N     . GLY A 1 101 ? 27.069  -16.162 36.229  1.00 75.87  ? 101 GLY A N     1 
ATOM   763  C  CA    . GLY A 1 101 ? 28.431  -15.708 36.010  1.00 71.47  ? 101 GLY A CA    1 
ATOM   764  C  C     . GLY A 1 101 ? 28.958  -14.936 37.207  1.00 77.26  ? 101 GLY A C     1 
ATOM   765  O  O     . GLY A 1 101 ? 28.762  -15.319 38.366  1.00 82.66  ? 101 GLY A O     1 
ATOM   766  N  N     . GLU A 1 102 ? 29.640  -13.824 36.923  1.00 78.18  ? 102 GLU A N     1 
ATOM   767  C  CA    . GLU A 1 102 ? 30.222  -13.024 37.995  1.00 80.89  ? 102 GLU A CA    1 
ATOM   768  C  C     . GLU A 1 102 ? 29.152  -12.301 38.807  1.00 83.44  ? 102 GLU A C     1 
ATOM   769  O  O     . GLU A 1 102 ? 29.345  -12.055 40.004  1.00 92.79  ? 102 GLU A O     1 
ATOM   770  C  CB    . GLU A 1 102 ? 31.229  -12.025 37.414  1.00 80.35  ? 102 GLU A CB    1 
ATOM   771  C  CG    . GLU A 1 102 ? 32.702  -12.411 37.606  1.00 93.40  ? 102 GLU A CG    1 
ATOM   772  C  CD    . GLU A 1 102 ? 33.673  -11.276 37.257  1.00 109.33 ? 102 GLU A CD    1 
ATOM   773  O  OE1   . GLU A 1 102 ? 33.381  -10.112 37.623  1.00 108.44 ? 102 GLU A OE1   1 
ATOM   774  O  OE2   . GLU A 1 102 ? 34.724  -11.549 36.621  1.00 100.51 ? 102 GLU A OE2   1 
ATOM   775  N  N     . LEU A 1 103 ? 28.014  -11.977 38.191  1.00 71.86  ? 103 LEU A N     1 
ATOM   776  C  CA    . LEU A 1 103 ? 26.958  -11.202 38.843  1.00 73.47  ? 103 LEU A CA    1 
ATOM   777  C  C     . LEU A 1 103 ? 26.040  -12.146 39.615  1.00 77.83  ? 103 LEU A C     1 
ATOM   778  O  O     . LEU A 1 103 ? 24.935  -12.487 39.190  1.00 81.75  ? 103 LEU A O     1 
ATOM   779  C  CB    . LEU A 1 103 ? 26.194  -10.389 37.810  1.00 75.54  ? 103 LEU A CB    1 
ATOM   780  C  CG    . LEU A 1 103 ? 27.089  -9.460  36.997  1.00 73.96  ? 103 LEU A CG    1 
ATOM   781  C  CD1   . LEU A 1 103 ? 27.207  -9.933  35.574  1.00 71.10  ? 103 LEU A CD1   1 
ATOM   782  C  CD2   . LEU A 1 103 ? 26.546  -8.052  37.037  1.00 76.62  ? 103 LEU A CD2   1 
ATOM   783  N  N     . ARG A 1 104 ? 26.510  -12.564 40.787  1.00 78.96  ? 104 ARG A N     1 
ATOM   784  C  CA    . ARG A 1 104 ? 25.771  -13.505 41.624  1.00 82.32  ? 104 ARG A CA    1 
ATOM   785  C  C     . ARG A 1 104 ? 24.832  -12.779 42.584  1.00 86.34  ? 104 ARG A C     1 
ATOM   786  O  O     . ARG A 1 104 ? 23.621  -13.037 42.608  1.00 79.35  ? 104 ARG A O     1 
ATOM   787  C  CB    . ARG A 1 104 ? 26.760  -14.393 42.387  1.00 83.92  ? 104 ARG A CB    1 
ATOM   788  C  CG    . ARG A 1 104 ? 26.272  -15.806 42.625  1.00 88.73  ? 104 ARG A CG    1 
ATOM   789  C  CD    . ARG A 1 104 ? 27.441  -16.781 42.610  1.00 101.45 ? 104 ARG A CD    1 
ATOM   790  N  NE    . ARG A 1 104 ? 28.363  -16.485 41.516  1.00 98.33  ? 104 ARG A NE    1 
ATOM   791  C  CZ    . ARG A 1 104 ? 29.678  -16.651 41.572  1.00 93.38  ? 104 ARG A CZ    1 
ATOM   792  N  NH1   . ARG A 1 104 ? 30.270  -17.134 42.654  1.00 91.78  ? 104 ARG A NH1   1 
ATOM   793  N  NH2   . ARG A 1 104 ? 30.419  -16.324 40.516  1.00 82.22  ? 104 ARG A NH2   1 
ATOM   794  N  N     . LYS A 1 105 ? 25.387  -11.863 43.378  1.00 89.16  ? 105 LYS A N     1 
ATOM   795  C  CA    . LYS A 1 105 ? 24.579  -11.112 44.328  1.00 82.62  ? 105 LYS A CA    1 
ATOM   796  C  C     . LYS A 1 105 ? 23.566  -10.225 43.617  1.00 81.92  ? 105 LYS A C     1 
ATOM   797  O  O     . LYS A 1 105 ? 22.463  -10.016 44.135  1.00 80.36  ? 105 LYS A O     1 
ATOM   798  C  CB    . LYS A 1 105 ? 25.491  -10.280 45.230  1.00 85.26  ? 105 LYS A CB    1 
ATOM   799  C  CG    . LYS A 1 105 ? 26.503  -11.113 46.013  1.00 93.44  ? 105 LYS A CG    1 
ATOM   800  C  CD    . LYS A 1 105 ? 27.913  -10.927 45.454  1.00 101.49 ? 105 LYS A CD    1 
ATOM   801  C  CE    . LYS A 1 105 ? 28.989  -11.396 46.421  1.00 103.29 ? 105 LYS A CE    1 
ATOM   802  N  NZ    . LYS A 1 105 ? 30.349  -11.302 45.810  1.00 108.92 ? 105 LYS A NZ    1 
ATOM   803  N  N     . GLU A 1 106 ? 23.916  -9.705  42.435  1.00 78.05  ? 106 GLU A N     1 
ATOM   804  C  CA    . GLU A 1 106 ? 22.996  -8.846  41.693  1.00 78.35  ? 106 GLU A CA    1 
ATOM   805  C  C     . GLU A 1 106 ? 21.773  -9.623  41.228  1.00 76.75  ? 106 GLU A C     1 
ATOM   806  O  O     . GLU A 1 106 ? 20.634  -9.159  41.367  1.00 75.64  ? 106 GLU A O     1 
ATOM   807  C  CB    . GLU A 1 106 ? 23.714  -8.212  40.501  1.00 81.72  ? 106 GLU A CB    1 
ATOM   808  C  CG    . GLU A 1 106 ? 24.960  -7.429  40.879  1.00 79.32  ? 106 GLU A CG    1 
ATOM   809  C  CD    . GLU A 1 106 ? 26.213  -8.283  40.859  1.00 87.95  ? 106 GLU A CD    1 
ATOM   810  O  OE1   . GLU A 1 106 ? 26.260  -9.303  41.585  1.00 90.32  ? 106 GLU A OE1   1 
ATOM   811  O  OE2   . GLU A 1 106 ? 27.156  -7.928  40.119  1.00 86.89  ? 106 GLU A OE2   1 
ATOM   812  N  N     . LEU A 1 107 ? 21.989  -10.814 40.670  1.00 75.33  ? 107 LEU A N     1 
ATOM   813  C  CA    . LEU A 1 107 ? 20.856  -11.658 40.322  1.00 74.28  ? 107 LEU A CA    1 
ATOM   814  C  C     . LEU A 1 107 ? 20.068  -12.053 41.562  1.00 72.34  ? 107 LEU A C     1 
ATOM   815  O  O     . LEU A 1 107 ? 18.837  -12.147 41.508  1.00 67.40  ? 107 LEU A O     1 
ATOM   816  C  CB    . LEU A 1 107 ? 21.333  -12.900 39.572  1.00 72.98  ? 107 LEU A CB    1 
ATOM   817  C  CG    . LEU A 1 107 ? 20.261  -13.956 39.334  1.00 62.75  ? 107 LEU A CG    1 
ATOM   818  C  CD1   . LEU A 1 107 ? 19.224  -13.401 38.382  1.00 63.40  ? 107 LEU A CD1   1 
ATOM   819  C  CD2   . LEU A 1 107 ? 20.879  -15.221 38.789  1.00 70.61  ? 107 LEU A CD2   1 
ATOM   820  N  N     . GLY A 1 108 ? 20.752  -12.281 42.686  1.00 72.13  ? 108 GLY A N     1 
ATOM   821  C  CA    . GLY A 1 108 ? 20.037  -12.589 43.916  1.00 73.83  ? 108 GLY A CA    1 
ATOM   822  C  C     . GLY A 1 108 ? 19.105  -11.470 44.342  1.00 74.93  ? 108 GLY A C     1 
ATOM   823  O  O     . GLY A 1 108 ? 17.929  -11.697 44.643  1.00 76.37  ? 108 GLY A O     1 
ATOM   824  N  N     . SER A 1 109 ? 19.624  -10.243 44.380  1.00 72.00  ? 109 SER A N     1 
ATOM   825  C  CA    . SER A 1 109 ? 18.791  -9.086  44.691  1.00 74.18  ? 109 SER A CA    1 
ATOM   826  C  C     . SER A 1 109 ? 17.635  -8.963  43.709  1.00 79.25  ? 109 SER A C     1 
ATOM   827  O  O     . SER A 1 109 ? 16.502  -8.647  44.100  1.00 81.41  ? 109 SER A O     1 
ATOM   828  C  CB    . SER A 1 109 ? 19.637  -7.812  44.674  1.00 75.05  ? 109 SER A CB    1 
ATOM   829  O  OG    . SER A 1 109 ? 20.325  -7.633  45.898  1.00 93.35  ? 109 SER A OG    1 
ATOM   830  N  N     . LEU A 1 110 ? 17.899  -9.217  42.425  1.00 78.98  ? 110 LEU A N     1 
ATOM   831  C  CA    . LEU A 1 110 ? 16.847  -9.077  41.428  1.00 72.78  ? 110 LEU A CA    1 
ATOM   832  C  C     . LEU A 1 110 ? 15.741  -10.102 41.650  1.00 74.03  ? 110 LEU A C     1 
ATOM   833  O  O     . LEU A 1 110 ? 14.556  -9.763  41.574  1.00 77.72  ? 110 LEU A O     1 
ATOM   834  C  CB    . LEU A 1 110 ? 17.436  -9.203  40.025  1.00 73.40  ? 110 LEU A CB    1 
ATOM   835  C  CG    . LEU A 1 110 ? 16.457  -8.966  38.874  1.00 67.41  ? 110 LEU A CG    1 
ATOM   836  C  CD1   . LEU A 1 110 ? 15.581  -7.761  39.166  1.00 67.80  ? 110 LEU A CD1   1 
ATOM   837  C  CD2   . LEU A 1 110 ? 17.207  -8.782  37.572  1.00 65.38  ? 110 LEU A CD2   1 
ATOM   838  N  N     . VAL A 1 111 ? 16.102  -11.356 41.942  1.00 76.59  ? 111 VAL A N     1 
ATOM   839  C  CA    . VAL A 1 111 ? 15.074  -12.378 42.132  1.00 77.52  ? 111 VAL A CA    1 
ATOM   840  C  C     . VAL A 1 111 ? 14.333  -12.150 43.442  1.00 79.20  ? 111 VAL A C     1 
ATOM   841  O  O     . VAL A 1 111 ? 13.146  -12.480 43.557  1.00 82.68  ? 111 VAL A O     1 
ATOM   842  C  CB    . VAL A 1 111 ? 15.662  -13.803 42.056  1.00 74.67  ? 111 VAL A CB    1 
ATOM   843  C  CG1   . VAL A 1 111 ? 16.176  -14.098 40.656  1.00 69.43  ? 111 VAL A CG1   1 
ATOM   844  C  CG2   . VAL A 1 111 ? 16.746  -14.018 43.098  1.00 77.75  ? 111 VAL A CG2   1 
ATOM   845  N  N     . GLU A 1 112 ? 14.998  -11.560 44.438  1.00 76.96  ? 112 GLU A N     1 
ATOM   846  C  CA    . GLU A 1 112 ? 14.290  -11.148 45.645  1.00 82.31  ? 112 GLU A CA    1 
ATOM   847  C  C     . GLU A 1 112 ? 13.230  -10.100 45.324  1.00 82.19  ? 112 GLU A C     1 
ATOM   848  O  O     . GLU A 1 112 ? 12.070  -10.220 45.739  1.00 79.61  ? 112 GLU A O     1 
ATOM   849  C  CB    . GLU A 1 112 ? 15.288  -10.614 46.671  1.00 90.32  ? 112 GLU A CB    1 
ATOM   850  C  CG    . GLU A 1 112 ? 15.686  -11.639 47.717  1.00 104.97 ? 112 GLU A CG    1 
ATOM   851  C  CD    . GLU A 1 112 ? 14.554  -11.951 48.677  1.00 116.54 ? 112 GLU A CD    1 
ATOM   852  O  OE1   . GLU A 1 112 ? 13.743  -12.855 48.369  1.00 109.85 ? 112 GLU A OE1   1 
ATOM   853  O  OE2   . GLU A 1 112 ? 14.479  -11.287 49.737  1.00 122.01 ? 112 GLU A OE2   1 
ATOM   854  N  N     . LYS A 1 113 ? 13.615  -9.068  44.570  1.00 82.56  ? 113 LYS A N     1 
ATOM   855  C  CA    . LYS A 1 113 ? 12.665  -8.026  44.194  1.00 77.49  ? 113 LYS A CA    1 
ATOM   856  C  C     . LYS A 1 113 ? 11.534  -8.571  43.323  1.00 80.35  ? 113 LYS A C     1 
ATOM   857  O  O     . LYS A 1 113 ? 10.400  -8.086  43.415  1.00 82.08  ? 113 LYS A O     1 
ATOM   858  C  CB    . LYS A 1 113 ? 13.404  -6.889  43.482  1.00 73.84  ? 113 LYS A CB    1 
ATOM   859  C  CG    . LYS A 1 113 ? 14.225  -6.014  44.424  1.00 76.69  ? 113 LYS A CG    1 
ATOM   860  C  CD    . LYS A 1 113 ? 14.644  -4.694  43.784  1.00 83.87  ? 113 LYS A CD    1 
ATOM   861  C  CE    . LYS A 1 113 ? 16.153  -4.587  43.616  1.00 77.56  ? 113 LYS A CE    1 
ATOM   862  N  NZ    . LYS A 1 113 ? 16.561  -3.163  43.445  1.00 73.36  ? 113 LYS A NZ    1 
ATOM   863  N  N     . ILE A 1 114 ? 11.813  -9.577  42.486  1.00 81.99  ? 114 ILE A N     1 
ATOM   864  C  CA    . ILE A 1 114 ? 10.772  -10.151 41.632  1.00 84.07  ? 114 ILE A CA    1 
ATOM   865  C  C     . ILE A 1 114 ? 9.798   -10.985 42.455  1.00 87.29  ? 114 ILE A C     1 
ATOM   866  O  O     . ILE A 1 114 ? 8.575   -10.882 42.286  1.00 86.11  ? 114 ILE A O     1 
ATOM   867  C  CB    . ILE A 1 114 ? 11.390  -10.986 40.495  1.00 76.88  ? 114 ILE A CB    1 
ATOM   868  C  CG1   . ILE A 1 114 ? 12.041  -10.089 39.445  1.00 78.83  ? 114 ILE A CG1   1 
ATOM   869  C  CG2   . ILE A 1 114 ? 10.331  -11.865 39.839  1.00 70.42  ? 114 ILE A CG2   1 
ATOM   870  C  CD1   . ILE A 1 114 ? 12.935  -10.855 38.488  1.00 74.95  ? 114 ILE A CD1   1 
ATOM   871  N  N     . LYS A 1 115 ? 10.320  -11.841 43.341  1.00 84.90  ? 115 LYS A N     1 
ATOM   872  C  CA    . LYS A 1 115 ? 9.458   -12.542 44.286  1.00 82.65  ? 115 LYS A CA    1 
ATOM   873  C  C     . LYS A 1 115 ? 8.622   -11.565 45.097  1.00 88.38  ? 115 LYS A C     1 
ATOM   874  O  O     . LYS A 1 115 ? 7.472   -11.865 45.435  1.00 88.21  ? 115 LYS A O     1 
ATOM   875  C  CB    . LYS A 1 115 ? 10.300  -13.417 45.212  1.00 81.40  ? 115 LYS A CB    1 
ATOM   876  C  CG    . LYS A 1 115 ? 10.585  -14.796 44.655  1.00 91.67  ? 115 LYS A CG    1 
ATOM   877  C  CD    . LYS A 1 115 ? 11.391  -15.639 45.632  1.00 91.26  ? 115 LYS A CD    1 
ATOM   878  C  CE    . LYS A 1 115 ? 12.122  -16.759 44.907  1.00 81.75  ? 115 LYS A CE    1 
ATOM   879  N  NZ    . LYS A 1 115 ? 13.171  -17.374 45.756  1.00 97.32  ? 115 LYS A NZ    1 
ATOM   880  N  N     . GLY A 1 116 ? 9.180   -10.390 45.406  1.00 88.69  ? 116 GLY A N     1 
ATOM   881  C  CA    . GLY A 1 116 ? 8.413   -9.369  46.098  1.00 78.96  ? 116 GLY A CA    1 
ATOM   882  C  C     . GLY A 1 116 ? 7.118   -9.017  45.395  1.00 82.06  ? 116 GLY A C     1 
ATOM   883  O  O     . GLY A 1 116 ? 6.120   -8.704  46.047  1.00 88.94  ? 116 GLY A O     1 
ATOM   884  N  N     . LEU A 1 117 ? 7.104   -9.085  44.066  1.00 84.56  ? 117 LEU A N     1 
ATOM   885  C  CA    . LEU A 1 117 ? 5.913   -8.747  43.297  1.00 87.37  ? 117 LEU A CA    1 
ATOM   886  C  C     . LEU A 1 117 ? 4.858   -9.846  43.308  1.00 87.32  ? 117 LEU A C     1 
ATOM   887  O  O     . LEU A 1 117 ? 3.823   -9.691  42.652  1.00 87.92  ? 117 LEU A O     1 
ATOM   888  C  CB    . LEU A 1 117 ? 6.292   -8.415  41.851  1.00 88.75  ? 117 LEU A CB    1 
ATOM   889  C  CG    . LEU A 1 117 ? 7.404   -7.383  41.656  1.00 89.61  ? 117 LEU A CG    1 
ATOM   890  C  CD1   . LEU A 1 117 ? 7.498   -6.975  40.191  1.00 85.83  ? 117 LEU A CD1   1 
ATOM   891  C  CD2   . LEU A 1 117 ? 7.159   -6.169  42.542  1.00 87.57  ? 117 LEU A CD2   1 
ATOM   892  N  N     . GLN A 1 118 ? 5.087   -10.948 44.016  1.00 88.65  ? 118 GLN A N     1 
ATOM   893  C  CA    . GLN A 1 118 ? 4.102   -12.023 44.069  1.00 90.43  ? 118 GLN A CA    1 
ATOM   894  C  C     . GLN A 1 118 ? 3.873   -12.483 45.510  1.00 88.52  ? 118 GLN A C     1 
ATOM   895  O  O     . GLN A 1 118 ? 3.314   -11.744 46.326  1.00 82.68  ? 118 GLN A O     1 
ATOM   896  C  CB    . GLN A 1 118 ? 4.536   -13.203 43.189  1.00 81.28  ? 118 GLN A CB    1 
ATOM   897  C  CG    . GLN A 1 118 ? 5.486   -12.822 42.059  1.00 82.21  ? 118 GLN A CG    1 
ATOM   898  C  CD    . GLN A 1 118 ? 6.004   -14.022 41.277  1.00 91.68  ? 118 GLN A CD    1 
ATOM   899  O  OE1   . GLN A 1 118 ? 5.237   -14.725 40.613  1.00 93.18  ? 118 GLN A OE1   1 
ATOM   900  N  NE2   . GLN A 1 118 ? 7.311   -14.265 41.360  1.00 86.95  ? 118 GLN A NE2   1 
ATOM   901  O  "O5'" . G   B 2 1   ? 10.128  -27.804 0.802   1.00 146.90 ? 1   G   B "O5'" 1 
ATOM   902  C  "C5'" . G   B 2 1   ? 9.179   -26.848 0.348   1.00 147.72 ? 1   G   B "C5'" 1 
ATOM   903  C  "C4'" . G   B 2 1   ? 7.845   -27.489 0.060   1.00 145.92 ? 1   G   B "C4'" 1 
ATOM   904  O  "O4'" . G   B 2 1   ? 7.967   -28.390 -1.079  1.00 147.39 ? 1   G   B "O4'" 1 
ATOM   905  C  "C3'" . G   B 2 1   ? 7.286   -28.364 1.175   1.00 148.17 ? 1   G   B "C3'" 1 
ATOM   906  O  "O3'" . G   B 2 1   ? 6.616   -27.621 2.191   1.00 150.28 ? 1   G   B "O3'" 1 
ATOM   907  C  "C2'" . G   B 2 1   ? 6.384   -29.327 0.414   1.00 146.07 ? 1   G   B "C2'" 1 
ATOM   908  O  "O2'" . G   B 2 1   ? 5.174   -28.681 0.046   1.00 140.16 ? 1   G   B "O2'" 1 
ATOM   909  C  "C1'" . G   B 2 1   ? 7.204   -29.558 -0.857  1.00 146.49 ? 1   G   B "C1'" 1 
ATOM   910  N  N9    . G   B 2 1   ? 8.148   -30.691 -0.727  1.00 143.71 ? 1   G   B N9    1 
ATOM   911  C  C8    . G   B 2 1   ? 9.479   -30.640 -1.067  1.00 139.79 ? 1   G   B C8    1 
ATOM   912  N  N7    . G   B 2 1   ? 10.118  -31.758 -0.864  1.00 141.74 ? 1   G   B N7    1 
ATOM   913  C  C5    . G   B 2 1   ? 9.153   -32.615 -0.361  1.00 144.78 ? 1   G   B C5    1 
ATOM   914  C  C6    . G   B 2 1   ? 9.265   -33.973 0.040   1.00 140.81 ? 1   G   B C6    1 
ATOM   915  O  O6    . G   B 2 1   ? 10.267  -34.698 0.028   1.00 131.67 ? 1   G   B O6    1 
ATOM   916  N  N1    . G   B 2 1   ? 8.049   -34.477 0.489   1.00 143.51 ? 1   G   B N1    1 
ATOM   917  C  C2    . G   B 2 1   ? 6.876   -33.764 0.546   1.00 143.65 ? 1   G   B C2    1 
ATOM   918  N  N2    . G   B 2 1   ? 5.793   -34.406 1.009   1.00 138.14 ? 1   G   B N2    1 
ATOM   919  N  N3    . G   B 2 1   ? 6.762   -32.498 0.171   1.00 143.90 ? 1   G   B N3    1 
ATOM   920  C  C4    . G   B 2 1   ? 7.928   -31.978 -0.272  1.00 144.76 ? 1   G   B C4    1 
ATOM   921  P  P     . G   B 2 2   ? 7.146   -27.627 3.716   1.00 147.16 ? 2   G   B P     1 
ATOM   922  O  OP1   . G   B 2 2   ? 7.629   -26.265 4.054   1.00 135.51 ? 2   G   B OP1   1 
ATOM   923  O  OP2   . G   B 2 2   ? 8.055   -28.782 3.914   1.00 150.71 ? 2   G   B OP2   1 
ATOM   924  O  "O5'" . G   B 2 2   ? 5.838   -27.892 4.587   1.00 132.31 ? 2   G   B "O5'" 1 
ATOM   925  C  "C5'" . G   B 2 2   ? 4.636   -28.344 3.982   1.00 134.54 ? 2   G   B "C5'" 1 
ATOM   926  C  "C4'" . G   B 2 2   ? 4.274   -29.732 4.444   1.00 137.29 ? 2   G   B "C4'" 1 
ATOM   927  O  "O4'" . G   B 2 2   ? 4.700   -30.709 3.461   1.00 139.80 ? 2   G   B "O4'" 1 
ATOM   928  C  "C3'" . G   B 2 2   ? 4.929   -30.199 5.732   1.00 135.30 ? 2   G   B "C3'" 1 
ATOM   929  O  "O3'" . G   B 2 2   ? 4.290   -29.691 6.887   1.00 136.02 ? 2   G   B "O3'" 1 
ATOM   930  C  "C2'" . G   B 2 2   ? 4.858   -31.716 5.612   1.00 134.59 ? 2   G   B "C2'" 1 
ATOM   931  O  "O2'" . G   B 2 2   ? 3.566   -32.189 5.962   1.00 133.84 ? 2   G   B "O2'" 1 
ATOM   932  C  "C1'" . G   B 2 2   ? 5.060   -31.914 4.107   1.00 140.53 ? 2   G   B "C1'" 1 
ATOM   933  N  N9    . G   B 2 2   ? 6.457   -32.250 3.758   1.00 144.28 ? 2   G   B N9    1 
ATOM   934  C  C8    . G   B 2 2   ? 7.338   -31.514 3.002   1.00 142.77 ? 2   G   B C8    1 
ATOM   935  N  N7    . G   B 2 2   ? 8.508   -32.081 2.860   1.00 138.88 ? 2   G   B N7    1 
ATOM   936  C  C5    . G   B 2 2   ? 8.396   -33.274 3.563   1.00 139.67 ? 2   G   B C5    1 
ATOM   937  C  C6    . G   B 2 2   ? 9.336   -34.321 3.775   1.00 138.07 ? 2   G   B C6    1 
ATOM   938  O  O6    . G   B 2 2   ? 10.502  -34.414 3.371   1.00 138.32 ? 2   G   B O6    1 
ATOM   939  N  N1    . G   B 2 2   ? 8.798   -35.347 4.548   1.00 136.12 ? 2   G   B N1    1 
ATOM   940  C  C2    . G   B 2 2   ? 7.520   -35.363 5.049   1.00 136.47 ? 2   G   B C2    1 
ATOM   941  N  N2    . G   B 2 2   ? 7.151   -36.419 5.778   1.00 128.64 ? 2   G   B N2    1 
ATOM   942  N  N3    . G   B 2 2   ? 6.639   -34.398 4.862   1.00 141.84 ? 2   G   B N3    1 
ATOM   943  C  C4    . G   B 2 2   ? 7.136   -33.392 4.117   1.00 142.90 ? 2   G   B C4    1 
ATOM   944  P  P     . A   B 2 3   ? 5.168   -29.248 8.154   1.00 137.14 ? 3   A   B P     1 
ATOM   945  O  OP1   . A   B 2 3   ? 4.427   -28.195 8.893   1.00 144.25 ? 3   A   B OP1   1 
ATOM   946  O  OP2   . A   B 2 3   ? 6.540   -28.970 7.659   1.00 135.67 ? 3   A   B OP2   1 
ATOM   947  O  "O5'" . A   B 2 3   ? 5.211   -30.553 9.064   1.00 130.03 ? 3   A   B "O5'" 1 
ATOM   948  C  "C5'" . A   B 2 3   ? 4.027   -31.287 9.342   1.00 128.27 ? 3   A   B "C5'" 1 
ATOM   949  C  "C4'" . A   B 2 3   ? 4.353   -32.701 9.748   1.00 130.36 ? 3   A   B "C4'" 1 
ATOM   950  O  "O4'" . A   B 2 3   ? 4.881   -33.422 8.608   1.00 133.53 ? 3   A   B "O4'" 1 
ATOM   951  C  "C3'" . A   B 2 3   ? 5.427   -32.840 10.814  1.00 132.35 ? 3   A   B "C3'" 1 
ATOM   952  O  "O3'" . A   B 2 3   ? 4.908   -32.680 12.123  1.00 131.37 ? 3   A   B "O3'" 1 
ATOM   953  C  "C2'" . A   B 2 3   ? 6.004   -34.227 10.548  1.00 131.45 ? 3   A   B "C2'" 1 
ATOM   954  O  "O2'" . A   B 2 3   ? 5.196   -35.234 11.139  1.00 130.41 ? 3   A   B "O2'" 1 
ATOM   955  C  "C1'" . A   B 2 3   ? 5.872   -34.335 9.027   1.00 133.62 ? 3   A   B "C1'" 1 
ATOM   956  N  N9    . A   B 2 3   ? 7.128   -34.039 8.307   1.00 135.32 ? 3   A   B N9    1 
ATOM   957  C  C8    . A   B 2 3   ? 7.390   -32.969 7.484   1.00 136.83 ? 3   A   B C8    1 
ATOM   958  N  N7    . A   B 2 3   ? 8.592   -32.974 6.958   1.00 135.56 ? 3   A   B N7    1 
ATOM   959  C  C5    . A   B 2 3   ? 9.164   -34.132 7.469   1.00 132.77 ? 3   A   B C5    1 
ATOM   960  C  C6    . A   B 2 3   ? 10.432  -34.713 7.291   1.00 127.02 ? 3   A   B C6    1 
ATOM   961  N  N6    . A   B 2 3   ? 11.387  -34.182 6.525   1.00 126.87 ? 3   A   B N6    1 
ATOM   962  N  N1    . A   B 2 3   ? 10.689  -35.870 7.937   1.00 125.67 ? 3   A   B N1    1 
ATOM   963  C  C2    . A   B 2 3   ? 9.727   -36.399 8.706   1.00 127.32 ? 3   A   B C2    1 
ATOM   964  N  N3    . A   B 2 3   ? 8.495   -35.953 8.951   1.00 127.51 ? 3   A   B N3    1 
ATOM   965  C  C4    . A   B 2 3   ? 8.273   -34.801 8.294   1.00 131.91 ? 3   A   B C4    1 
ATOM   966  P  P     . U   B 2 4   ? 5.623   -31.694 13.170  1.00 132.52 ? 4   U   B P     1 
ATOM   967  O  OP1   . U   B 2 4   ? 4.633   -31.369 14.227  1.00 137.39 ? 4   U   B OP1   1 
ATOM   968  O  OP2   . U   B 2 4   ? 6.266   -30.589 12.413  1.00 129.89 ? 4   U   B OP2   1 
ATOM   969  O  "O5'" . U   B 2 4   ? 6.766   -32.593 13.822  1.00 130.16 ? 4   U   B "O5'" 1 
ATOM   970  C  "C5'" . U   B 2 4   ? 6.437   -33.793 14.504  1.00 125.51 ? 4   U   B "C5'" 1 
ATOM   971  C  "C4'" . U   B 2 4   ? 7.597   -34.759 14.554  1.00 124.67 ? 4   U   B "C4'" 1 
ATOM   972  O  "O4'" . U   B 2 4   ? 7.977   -35.168 13.213  1.00 127.42 ? 4   U   B "O4'" 1 
ATOM   973  C  "C3'" . U   B 2 4   ? 8.894   -34.240 15.153  1.00 123.98 ? 4   U   B "C3'" 1 
ATOM   974  O  "O3'" . U   B 2 4   ? 8.879   -34.189 16.570  1.00 126.31 ? 4   U   B "O3'" 1 
ATOM   975  C  "C2'" . U   B 2 4   ? 9.919   -35.215 14.589  1.00 123.53 ? 4   U   B "C2'" 1 
ATOM   976  O  "O2'" . U   B 2 4   ? 9.875   -36.443 15.302  1.00 117.32 ? 4   U   B "O2'" 1 
ATOM   977  C  "C1'" . U   B 2 4   ? 9.364   -35.453 13.179  1.00 129.67 ? 4   U   B "C1'" 1 
ATOM   978  N  N1    . U   B 2 4   ? 10.021  -34.592 12.161  1.00 126.78 ? 4   U   B N1    1 
ATOM   979  C  C2    . U   B 2 4   ? 11.307  -34.923 11.749  1.00 119.67 ? 4   U   B C2    1 
ATOM   980  O  O2    . U   B 2 4   ? 11.928  -35.881 12.179  1.00 117.63 ? 4   U   B O2    1 
ATOM   981  N  N3    . U   B 2 4   ? 11.869  -34.093 10.808  1.00 117.78 ? 4   U   B N3    1 
ATOM   982  C  C4    . U   B 2 4   ? 11.279  -32.977 10.241  1.00 118.78 ? 4   U   B C4    1 
ATOM   983  O  O4    . U   B 2 4   ? 11.897  -32.315 9.403   1.00 117.87 ? 4   U   B O4    1 
ATOM   984  C  C5    . U   B 2 4   ? 9.955   -32.700 10.712  1.00 120.36 ? 4   U   B C5    1 
ATOM   985  C  C6    . U   B 2 4   ? 9.385   -33.494 11.628  1.00 124.15 ? 4   U   B C6    1 
ATOM   986  P  P     . G   B 2 5   ? 9.422   -32.884 17.340  1.00 124.31 ? 5   G   B P     1 
ATOM   987  O  OP1   . G   B 2 5   ? 8.820   -32.863 18.698  1.00 123.07 ? 5   G   B OP1   1 
ATOM   988  O  OP2   . G   B 2 5   ? 9.280   -31.720 16.428  1.00 123.25 ? 5   G   B OP2   1 
ATOM   989  O  "O5'" . G   B 2 5   ? 10.974  -33.165 17.539  1.00 109.86 ? 5   G   B "O5'" 1 
ATOM   990  C  "C5'" . G   B 2 5   ? 11.411  -34.214 18.386  1.00 109.46 ? 5   G   B "C5'" 1 
ATOM   991  C  "C4'" . G   B 2 5   ? 12.716  -34.794 17.908  1.00 109.46 ? 5   G   B "C4'" 1 
ATOM   992  O  "O4'" . G   B 2 5   ? 12.659  -35.002 16.478  1.00 106.57 ? 5   G   B "O4'" 1 
ATOM   993  C  "C3'" . G   B 2 5   ? 13.947  -33.925 18.110  1.00 103.80 ? 5   G   B "C3'" 1 
ATOM   994  O  "O3'" . G   B 2 5   ? 14.471  -34.040 19.421  1.00 107.04 ? 5   G   B "O3'" 1 
ATOM   995  C  "C2'" . G   B 2 5   ? 14.906  -34.425 17.035  1.00 99.88  ? 5   G   B "C2'" 1 
ATOM   996  O  "O2'" . G   B 2 5   ? 15.623  -35.566 17.485  1.00 100.59 ? 5   G   B "O2'" 1 
ATOM   997  C  "C1'" . G   B 2 5   ? 13.946  -34.853 15.919  1.00 103.53 ? 5   G   B "C1'" 1 
ATOM   998  N  N9    . G   B 2 5   ? 13.883  -33.886 14.809  1.00 100.42 ? 5   G   B N9    1 
ATOM   999  C  C8    . G   B 2 5   ? 12.784  -33.184 14.385  1.00 106.22 ? 5   G   B C8    1 
ATOM   1000 N  N7    . G   B 2 5   ? 13.037  -32.413 13.362  1.00 106.93 ? 5   G   B N7    1 
ATOM   1001 C  C5    . G   B 2 5   ? 14.380  -32.629 13.089  1.00 98.28  ? 5   G   B C5    1 
ATOM   1002 C  C6    . G   B 2 5   ? 15.214  -32.072 12.087  1.00 95.29  ? 5   G   B C6    1 
ATOM   1003 O  O6    . G   B 2 5   ? 14.921  -31.244 11.213  1.00 93.68  ? 5   G   B O6    1 
ATOM   1004 N  N1    . G   B 2 5   ? 16.512  -32.569 12.171  1.00 92.37  ? 5   G   B N1    1 
ATOM   1005 C  C2    . G   B 2 5   ? 16.949  -33.489 13.095  1.00 93.76  ? 5   G   B C2    1 
ATOM   1006 N  N2    . G   B 2 5   ? 18.235  -33.858 13.031  1.00 89.87  ? 5   G   B N2    1 
ATOM   1007 N  N3    . G   B 2 5   ? 16.178  -34.014 14.031  1.00 92.60  ? 5   G   B N3    1 
ATOM   1008 C  C4    . G   B 2 5   ? 14.915  -33.544 13.969  1.00 95.73  ? 5   G   B C4    1 
ATOM   1009 P  P     . C   B 2 6   ? 14.965  -32.738 20.217  1.00 111.00 ? 6   C   B P     1 
ATOM   1010 O  OP1   . C   B 2 6   ? 14.961  -33.041 21.674  1.00 105.23 ? 6   C   B OP1   1 
ATOM   1011 O  OP2   . C   B 2 6   ? 14.190  -31.585 19.698  1.00 114.64 ? 6   C   B OP2   1 
ATOM   1012 O  "O5'" . C   B 2 6   ? 16.472  -32.552 19.743  1.00 100.72 ? 6   C   B "O5'" 1 
ATOM   1013 C  "C5'" . C   B 2 6   ? 17.407  -33.614 19.842  1.00 97.84  ? 6   C   B "C5'" 1 
ATOM   1014 C  "C4'" . C   B 2 6   ? 18.686  -33.260 19.133  1.00 99.64  ? 6   C   B "C4'" 1 
ATOM   1015 O  "O4'" . C   B 2 6   ? 18.520  -33.429 17.702  1.00 99.66  ? 6   C   B "O4'" 1 
ATOM   1016 C  "C3'" . C   B 2 6   ? 19.130  -31.816 19.280  1.00 102.77 ? 6   C   B "C3'" 1 
ATOM   1017 O  "O3'" . C   B 2 6   ? 19.789  -31.571 20.508  1.00 105.22 ? 6   C   B "O3'" 1 
ATOM   1018 C  "C2'" . C   B 2 6   ? 20.007  -31.612 18.052  1.00 96.87  ? 6   C   B "C2'" 1 
ATOM   1019 O  "O2'" . C   B 2 6   ? 21.286  -32.199 18.252  1.00 95.30  ? 6   C   B "O2'" 1 
ATOM   1020 C  "C1'" . C   B 2 6   ? 19.261  -32.443 17.011  1.00 92.32  ? 6   C   B "C1'" 1 
ATOM   1021 N  N1    . C   B 2 6   ? 18.325  -31.655 16.168  1.00 91.42  ? 6   C   B N1    1 
ATOM   1022 C  C2    . C   B 2 6   ? 18.791  -30.955 15.039  1.00 93.31  ? 6   C   B C2    1 
ATOM   1023 O  O2    . C   B 2 6   ? 20.007  -30.973 14.780  1.00 95.25  ? 6   C   B O2    1 
ATOM   1024 N  N3    . C   B 2 6   ? 17.903  -30.270 14.268  1.00 84.59  ? 6   C   B N3    1 
ATOM   1025 C  C4    . C   B 2 6   ? 16.601  -30.281 14.581  1.00 87.49  ? 6   C   B C4    1 
ATOM   1026 N  N4    . C   B 2 6   ? 15.751  -29.603 13.806  1.00 85.25  ? 6   C   B N4    1 
ATOM   1027 C  C5    . C   B 2 6   ? 16.104  -30.989 15.714  1.00 95.02  ? 6   C   B C5    1 
ATOM   1028 C  C6    . C   B 2 6   ? 16.989  -31.658 16.464  1.00 93.97  ? 6   C   B C6    1 
ATOM   1029 P  P     . A   B 2 7   ? 19.429  -30.266 21.372  1.00 104.86 ? 7   A   B P     1 
ATOM   1030 O  OP1   . A   B 2 7   ? 19.621  -30.601 22.808  1.00 108.35 ? 7   A   B OP1   1 
ATOM   1031 O  OP2   . A   B 2 7   ? 18.112  -29.746 20.922  1.00 90.62  ? 7   A   B OP2   1 
ATOM   1032 O  "O5'" . A   B 2 7   ? 20.557  -29.230 20.941  1.00 98.32  ? 7   A   B "O5'" 1 
ATOM   1033 C  "C5'" . A   B 2 7   ? 21.836  -29.688 20.525  1.00 96.22  ? 7   A   B "C5'" 1 
ATOM   1034 C  "C4'" . A   B 2 7   ? 22.408  -28.800 19.450  1.00 100.24 ? 7   A   B "C4'" 1 
ATOM   1035 O  "O4'" . A   B 2 7   ? 21.830  -29.136 18.161  1.00 99.56  ? 7   A   B "O4'" 1 
ATOM   1036 C  "C3'" . A   B 2 7   ? 22.105  -27.322 19.613  1.00 98.01  ? 7   A   B "C3'" 1 
ATOM   1037 O  "O3'" . A   B 2 7   ? 22.988  -26.680 20.509  1.00 97.12  ? 7   A   B "O3'" 1 
ATOM   1038 C  "C2'" . A   B 2 7   ? 22.201  -26.800 18.190  1.00 91.87  ? 7   A   B "C2'" 1 
ATOM   1039 O  "O2'" . A   B 2 7   ? 23.560  -26.646 17.812  1.00 98.52  ? 7   A   B "O2'" 1 
ATOM   1040 C  "C1'" . A   B 2 7   ? 21.613  -27.963 17.406  1.00 87.77  ? 7   A   B "C1'" 1 
ATOM   1041 N  N9    . A   B 2 7   ? 20.162  -27.804 17.208  1.00 82.93  ? 7   A   B N9    1 
ATOM   1042 C  C8    . A   B 2 7   ? 19.141  -28.221 18.025  1.00 84.20  ? 7   A   B C8    1 
ATOM   1043 N  N7    . A   B 2 7   ? 17.943  -27.941 17.570  1.00 87.26  ? 7   A   B N7    1 
ATOM   1044 C  C5    . A   B 2 7   ? 18.193  -27.284 16.368  1.00 84.11  ? 7   A   B C5    1 
ATOM   1045 C  C6    . A   B 2 7   ? 17.345  -26.722 15.383  1.00 80.04  ? 7   A   B C6    1 
ATOM   1046 N  N6    . A   B 2 7   ? 16.008  -26.721 15.445  1.00 72.92  ? 7   A   B N6    1 
ATOM   1047 N  N1    . A   B 2 7   ? 17.927  -26.143 14.307  1.00 75.44  ? 7   A   B N1    1 
ATOM   1048 C  C2    . A   B 2 7   ? 19.266  -26.138 14.230  1.00 74.27  ? 7   A   B C2    1 
ATOM   1049 N  N3    . A   B 2 7   ? 20.166  -26.631 15.081  1.00 78.36  ? 7   A   B N3    1 
ATOM   1050 C  C4    . A   B 2 7   ? 19.558  -27.194 16.140  1.00 82.35  ? 7   A   B C4    1 
ATOM   1051 P  P     . G   B 2 8   ? 22.468  -25.452 21.397  1.00 102.24 ? 8   G   B P     1 
ATOM   1052 O  OP1   . G   B 2 8   ? 23.488  -25.241 22.460  1.00 100.70 ? 8   G   B OP1   1 
ATOM   1053 O  OP2   . G   B 2 8   ? 21.035  -25.688 21.743  1.00 92.22  ? 8   G   B OP2   1 
ATOM   1054 O  "O5'" . G   B 2 8   ? 22.524  -24.220 20.390  1.00 91.49  ? 8   G   B "O5'" 1 
ATOM   1055 C  "C5'" . G   B 2 8   ? 23.642  -24.035 19.529  1.00 80.12  ? 8   G   B "C5'" 1 
ATOM   1056 C  "C4'" . G   B 2 8   ? 23.278  -23.209 18.324  1.00 74.09  ? 8   G   B "C4'" 1 
ATOM   1057 O  "O4'" . G   B 2 8   ? 22.030  -23.702 17.754  1.00 70.40  ? 8   G   B "O4'" 1 
ATOM   1058 C  "C3'" . G   B 2 8   ? 23.062  -21.726 18.615  1.00 71.81  ? 8   G   B "C3'" 1 
ATOM   1059 O  "O3'" . G   B 2 8   ? 23.558  -20.947 17.537  1.00 66.82  ? 8   G   B "O3'" 1 
ATOM   1060 C  "C2'" . G   B 2 8   ? 21.546  -21.601 18.666  1.00 74.53  ? 8   G   B "C2'" 1 
ATOM   1061 O  "O2'" . G   B 2 8   ? 21.053  -20.315 18.357  1.00 75.01  ? 8   G   B "O2'" 1 
ATOM   1062 C  "C1'" . G   B 2 8   ? 21.113  -22.635 17.633  1.00 71.90  ? 8   G   B "C1'" 1 
ATOM   1063 N  N9    . G   B 2 8   ? 19.746  -23.113 17.864  1.00 68.42  ? 8   G   B N9    1 
ATOM   1064 C  C8    . G   B 2 8   ? 19.264  -23.686 19.014  1.00 69.50  ? 8   G   B C8    1 
ATOM   1065 N  N7    . G   B 2 8   ? 17.992  -23.971 18.950  1.00 68.04  ? 8   G   B N7    1 
ATOM   1066 C  C5    . G   B 2 8   ? 17.609  -23.539 17.689  1.00 63.25  ? 8   G   B C5    1 
ATOM   1067 C  C6    . G   B 2 8   ? 16.344  -23.586 17.055  1.00 62.41  ? 8   G   B C6    1 
ATOM   1068 O  O6    . G   B 2 8   ? 15.282  -24.034 17.504  1.00 61.75  ? 8   G   B O6    1 
ATOM   1069 N  N1    . G   B 2 8   ? 16.390  -23.041 15.776  1.00 61.68  ? 8   G   B N1    1 
ATOM   1070 C  C2    . G   B 2 8   ? 17.509  -22.520 15.178  1.00 60.14  ? 8   G   B C2    1 
ATOM   1071 N  N2    . G   B 2 8   ? 17.341  -22.042 13.936  1.00 56.58  ? 8   G   B N2    1 
ATOM   1072 N  N3    . G   B 2 8   ? 18.699  -22.472 15.757  1.00 63.49  ? 8   G   B N3    1 
ATOM   1073 C  C4    . G   B 2 8   ? 18.676  -22.998 17.004  1.00 64.98  ? 8   G   B C4    1 
ATOM   1074 P  P     . A   B 2 9   ? 24.598  -19.765 17.827  1.00 68.26  ? 9   A   B P     1 
ATOM   1075 O  OP1   . A   B 2 9   ? 25.934  -20.362 18.071  1.00 72.94  ? 9   A   B OP1   1 
ATOM   1076 O  OP2   . A   B 2 9   ? 24.003  -18.823 18.809  1.00 70.98  ? 9   A   B OP2   1 
ATOM   1077 O  "O5'" . A   B 2 9   ? 24.698  -19.033 16.429  1.00 52.12  ? 9   A   B "O5'" 1 
ATOM   1078 C  "C5'" . A   B 2 9   ? 25.393  -19.645 15.354  1.00 54.78  ? 9   A   B "C5'" 1 
ATOM   1079 C  "C4'" . A   B 2 9   ? 25.199  -18.855 14.094  1.00 56.46  ? 9   A   B "C4'" 1 
ATOM   1080 O  "O4'" . A   B 2 9   ? 23.831  -19.048 13.649  1.00 58.91  ? 9   A   B "O4'" 1 
ATOM   1081 C  "C3'" . A   B 2 9   ? 25.396  -17.348 14.256  1.00 53.02  ? 9   A   B "C3'" 1 
ATOM   1082 O  "O3'" . A   B 2 9   ? 25.970  -16.810 13.071  1.00 53.28  ? 9   A   B "O3'" 1 
ATOM   1083 C  "C2'" . A   B 2 9   ? 23.969  -16.832 14.432  1.00 55.24  ? 9   A   B "C2'" 1 
ATOM   1084 O  "O2'" . A   B 2 9   ? 23.770  -15.494 14.031  1.00 61.47  ? 9   A   B "O2'" 1 
ATOM   1085 C  "C1'" . A   B 2 9   ? 23.167  -17.803 13.568  1.00 55.13  ? 9   A   B "C1'" 1 
ATOM   1086 N  N9    . A   B 2 9   ? 21.786  -17.990 14.028  1.00 54.39  ? 9   A   B N9    1 
ATOM   1087 C  C8    . A   B 2 9   ? 21.357  -18.363 15.281  1.00 59.32  ? 9   A   B C8    1 
ATOM   1088 N  N7    . A   B 2 9   ? 20.052  -18.448 15.404  1.00 57.12  ? 9   A   B N7    1 
ATOM   1089 C  C5    . A   B 2 9   ? 19.582  -18.103 14.140  1.00 55.65  ? 9   A   B C5    1 
ATOM   1090 C  C6    . A   B 2 9   ? 18.284  -17.993 13.605  1.00 51.94  ? 9   A   B C6    1 
ATOM   1091 N  N6    . A   B 2 9   ? 17.166  -18.231 14.296  1.00 50.24  ? 9   A   B N6    1 
ATOM   1092 N  N1    . A   B 2 9   ? 18.172  -17.625 12.310  1.00 50.74  ? 9   A   B N1    1 
ATOM   1093 C  C2    . A   B 2 9   ? 19.294  -17.373 11.621  1.00 52.88  ? 9   A   B C2    1 
ATOM   1094 N  N3    . A   B 2 9   ? 20.565  -17.449 12.002  1.00 48.37  ? 9   A   B N3    1 
ATOM   1095 C  C4    . A   B 2 9   ? 20.640  -17.823 13.287  1.00 51.00  ? 9   A   B C4    1 
ATOM   1096 P  P     . G   B 2 10  ? 27.009  -15.579 13.129  1.00 60.73  ? 10  G   B P     1 
ATOM   1097 O  OP1   . G   B 2 10  ? 28.267  -15.990 13.807  1.00 59.77  ? 10  G   B OP1   1 
ATOM   1098 O  OP2   . G   B 2 10  ? 26.304  -14.360 13.579  1.00 54.50  ? 10  G   B OP2   1 
ATOM   1099 O  "O5'" . G   B 2 10  ? 27.351  -15.321 11.601  1.00 61.22  ? 10  G   B "O5'" 1 
ATOM   1100 C  "C5'" . G   B 2 10  ? 26.376  -14.771 10.731  1.00 57.74  ? 10  G   B "C5'" 1 
ATOM   1101 C  "C4'" . G   B 2 10  ? 25.272  -15.755 10.449  1.00 56.46  ? 10  G   B "C4'" 1 
ATOM   1102 O  "O4'" . G   B 2 10  ? 24.004  -15.181 10.840  1.00 53.73  ? 10  G   B "O4'" 1 
ATOM   1103 C  "C3'" . G   B 2 10  ? 25.072  -16.139 8.994   1.00 63.37  ? 10  G   B "C3'" 1 
ATOM   1104 O  "O3'" . G   B 2 10  ? 25.980  -17.129 8.555   1.00 59.99  ? 10  G   B "O3'" 1 
ATOM   1105 C  "C2'" . G   B 2 10  ? 23.617  -16.581 8.968   1.00 63.12  ? 10  G   B "C2'" 1 
ATOM   1106 O  "O2'" . G   B 2 10  ? 23.472  -17.890 9.498   1.00 65.35  ? 10  G   B "O2'" 1 
ATOM   1107 C  "C1'" . G   B 2 10  ? 22.995  -15.591 9.946   1.00 54.98  ? 10  G   B "C1'" 1 
ATOM   1108 N  N9    . G   B 2 10  ? 22.483  -14.398 9.256   1.00 58.68  ? 10  G   B N9    1 
ATOM   1109 C  C8    . G   B 2 10  ? 22.974  -13.114 9.266   1.00 58.40  ? 10  G   B C8    1 
ATOM   1110 N  N7    . G   B 2 10  ? 22.258  -12.296 8.544   1.00 62.49  ? 10  G   B N7    1 
ATOM   1111 C  C5    . G   B 2 10  ? 21.247  -13.104 8.028   1.00 64.72  ? 10  G   B C5    1 
ATOM   1112 C  C6    . G   B 2 10  ? 20.159  -12.809 7.173   1.00 63.06  ? 10  G   B C6    1 
ATOM   1113 O  O6    . G   B 2 10  ? 19.857  -11.721 6.676   1.00 70.12  ? 10  G   B O6    1 
ATOM   1114 N  N1    . G   B 2 10  ? 19.384  -13.936 6.912   1.00 61.08  ? 10  G   B N1    1 
ATOM   1115 C  C2    . G   B 2 10  ? 19.616  -15.194 7.411   1.00 63.18  ? 10  G   B C2    1 
ATOM   1116 N  N2    . G   B 2 10  ? 18.774  -16.172 7.059   1.00 64.66  ? 10  G   B N2    1 
ATOM   1117 N  N3    . G   B 2 10  ? 20.619  -15.485 8.210   1.00 62.56  ? 10  G   B N3    1 
ATOM   1118 C  C4    . G   B 2 10  ? 21.378  -14.401 8.462   1.00 63.80  ? 10  G   B C4    1 
ATOM   1119 P  P     . A   B 2 11  ? 26.408  -17.185 7.011   1.00 70.57  ? 11  A   B P     1 
ATOM   1120 O  OP1   . A   B 2 11  ? 27.504  -18.184 6.873   1.00 75.51  ? 11  A   B OP1   1 
ATOM   1121 O  OP2   . A   B 2 11  ? 26.618  -15.787 6.551   1.00 67.54  ? 11  A   B OP2   1 
ATOM   1122 O  "O5'" . A   B 2 11  ? 25.099  -17.729 6.281   1.00 67.94  ? 11  A   B "O5'" 1 
ATOM   1123 C  "C5'" . A   B 2 11  ? 24.654  -19.066 6.467   1.00 63.25  ? 11  A   B "C5'" 1 
ATOM   1124 C  "C4'" . A   B 2 11  ? 23.408  -19.346 5.664   1.00 69.56  ? 11  A   B "C4'" 1 
ATOM   1125 O  "O4'" . A   B 2 11  ? 22.340  -18.466 6.097   1.00 67.99  ? 11  A   B "O4'" 1 
ATOM   1126 C  "C3'" . A   B 2 11  ? 23.505  -19.099 4.164   1.00 75.66  ? 11  A   B "C3'" 1 
ATOM   1127 O  "O3'" . A   B 2 11  ? 24.110  -20.172 3.465   1.00 80.48  ? 11  A   B "O3'" 1 
ATOM   1128 C  "C2'" . A   B 2 11  ? 22.054  -18.862 3.771   1.00 73.58  ? 11  A   B "C2'" 1 
ATOM   1129 O  "O2'" . A   B 2 11  ? 21.353  -20.093 3.666   1.00 74.97  ? 11  A   B "O2'" 1 
ATOM   1130 C  "C1'" . A   B 2 11  ? 21.532  -18.110 4.995   1.00 68.58  ? 11  A   B "C1'" 1 
ATOM   1131 N  N9    . A   B 2 11  ? 21.605  -16.651 4.813   1.00 64.80  ? 11  A   B N9    1 
ATOM   1132 C  C8    . A   B 2 11  ? 22.518  -15.766 5.330   1.00 70.34  ? 11  A   B C8    1 
ATOM   1133 N  N7    . A   B 2 11  ? 22.302  -14.517 4.986   1.00 69.92  ? 11  A   B N7    1 
ATOM   1134 C  C5    . A   B 2 11  ? 21.172  -14.596 4.189   1.00 67.46  ? 11  A   B C5    1 
ATOM   1135 C  C6    . A   B 2 11  ? 20.431  -13.625 3.503   1.00 71.37  ? 11  A   B C6    1 
ATOM   1136 N  N6    . A   B 2 11  ? 20.733  -12.326 3.512   1.00 71.58  ? 11  A   B N6    1 
ATOM   1137 N  N1    . A   B 2 11  ? 19.357  -14.033 2.793   1.00 70.48  ? 11  A   B N1    1 
ATOM   1138 C  C2    . A   B 2 11  ? 19.053  -15.334 2.778   1.00 72.23  ? 11  A   B C2    1 
ATOM   1139 N  N3    . A   B 2 11  ? 19.675  -16.343 3.381   1.00 73.77  ? 11  A   B N3    1 
ATOM   1140 C  C4    . A   B 2 11  ? 20.736  -15.900 4.073   1.00 66.69  ? 11  A   B C4    1 
ATOM   1141 P  P     . A   B 2 12  ? 24.961  -19.889 2.132   1.00 85.80  ? 12  A   B P     1 
ATOM   1142 O  OP1   . A   B 2 12  ? 25.858  -21.052 1.908   1.00 90.85  ? 12  A   B OP1   1 
ATOM   1143 O  OP2   . A   B 2 12  ? 25.564  -18.538 2.271   1.00 86.68  ? 12  A   B OP2   1 
ATOM   1144 O  "O5'" . A   B 2 12  ? 23.863  -19.842 0.974   1.00 74.73  ? 12  A   B "O5'" 1 
ATOM   1145 C  "C5'" . A   B 2 12  ? 23.080  -20.986 0.663   1.00 79.98  ? 12  A   B "C5'" 1 
ATOM   1146 C  "C4'" . A   B 2 12  ? 21.947  -20.654 -0.280  1.00 82.16  ? 12  A   B "C4'" 1 
ATOM   1147 O  "O4'" . A   B 2 12  ? 21.033  -19.723 0.356   1.00 78.43  ? 12  A   B "O4'" 1 
ATOM   1148 C  "C3'" . A   B 2 12  ? 22.334  -19.965 -1.581  1.00 83.28  ? 12  A   B "C3'" 1 
ATOM   1149 O  "O3'" . A   B 2 12  ? 22.797  -20.869 -2.569  1.00 84.43  ? 12  A   B "O3'" 1 
ATOM   1150 C  "C2'" . A   B 2 12  ? 21.054  -19.237 -1.969  1.00 80.85  ? 12  A   B "C2'" 1 
ATOM   1151 O  "O2'" . A   B 2 12  ? 20.122  -20.131 -2.560  1.00 78.64  ? 12  A   B "O2'" 1 
ATOM   1152 C  "C1'" . A   B 2 12  ? 20.517  -18.821 -0.600  1.00 81.65  ? 12  A   B "C1'" 1 
ATOM   1153 N  N9    . A   B 2 12  ? 20.930  -17.456 -0.221  1.00 78.38  ? 12  A   B N9    1 
ATOM   1154 C  C8    . A   B 2 12  ? 21.799  -17.115 0.787   1.00 79.16  ? 12  A   B C8    1 
ATOM   1155 N  N7    . A   B 2 12  ? 21.983  -15.825 0.922   1.00 77.99  ? 12  A   B N7    1 
ATOM   1156 C  C5    . A   B 2 12  ? 21.173  -15.276 -0.060  1.00 75.15  ? 12  A   B C5    1 
ATOM   1157 C  C6    . A   B 2 12  ? 20.926  -13.945 -0.431  1.00 75.90  ? 12  A   B C6    1 
ATOM   1158 N  N6    . A   B 2 12  ? 21.496  -12.897 0.168   1.00 73.31  ? 12  A   B N6    1 
ATOM   1159 N  N1    . A   B 2 12  ? 20.069  -13.726 -1.450  1.00 77.02  ? 12  A   B N1    1 
ATOM   1160 C  C2    . A   B 2 12  ? 19.501  -14.782 -2.051  1.00 78.51  ? 12  A   B C2    1 
ATOM   1161 N  N3    . A   B 2 12  ? 19.656  -16.081 -1.790  1.00 72.96  ? 12  A   B N3    1 
ATOM   1162 C  C4    . A   B 2 12  ? 20.514  -16.264 -0.771  1.00 72.53  ? 12  A   B C4    1 
ATOM   1163 P  P     . C   B 2 13  ? 23.995  -20.447 -3.554  1.00 91.96  ? 13  C   B P     1 
ATOM   1164 O  OP1   . C   B 2 13  ? 24.416  -21.663 -4.297  1.00 96.12  ? 13  C   B OP1   1 
ATOM   1165 O  OP2   . C   B 2 13  ? 25.012  -19.695 -2.774  1.00 93.90  ? 13  C   B OP2   1 
ATOM   1166 O  "O5'" . C   B 2 13  ? 23.311  -19.437 -4.580  1.00 92.80  ? 13  C   B "O5'" 1 
ATOM   1167 C  "C5'" . C   B 2 13  ? 22.350  -19.896 -5.522  1.00 94.02  ? 13  C   B "C5'" 1 
ATOM   1168 C  "C4'" . C   B 2 13  ? 21.807  -18.771 -6.369  1.00 86.97  ? 13  C   B "C4'" 1 
ATOM   1169 O  "O4'" . C   B 2 13  ? 21.037  -17.863 -5.540  1.00 79.81  ? 13  C   B "O4'" 1 
ATOM   1170 C  "C3'" . C   B 2 13  ? 22.843  -17.881 -7.043  1.00 86.50  ? 13  C   B "C3'" 1 
ATOM   1171 O  "O3'" . C   B 2 13  ? 23.349  -18.437 -8.248  1.00 82.57  ? 13  C   B "O3'" 1 
ATOM   1172 C  "C2'" . C   B 2 13  ? 22.081  -16.578 -7.244  1.00 90.94  ? 13  C   B "C2'" 1 
ATOM   1173 O  "O2'" . C   B 2 13  ? 21.230  -16.662 -8.378  1.00 92.92  ? 13  C   B "O2'" 1 
ATOM   1174 C  "C1'" . C   B 2 13  ? 21.214  -16.535 -5.982  1.00 85.32  ? 13  C   B "C1'" 1 
ATOM   1175 N  N1    . C   B 2 13  ? 21.863  -15.764 -4.898  1.00 81.39  ? 13  C   B N1    1 
ATOM   1176 C  C2    . C   B 2 13  ? 21.809  -14.368 -4.923  1.00 82.70  ? 13  C   B C2    1 
ATOM   1177 O  O2    . C   B 2 13  ? 21.206  -13.790 -5.839  1.00 83.07  ? 13  C   B O2    1 
ATOM   1178 N  N3    . C   B 2 13  ? 22.411  -13.667 -3.933  1.00 80.68  ? 13  C   B N3    1 
ATOM   1179 C  C4    . C   B 2 13  ? 23.050  -14.302 -2.952  1.00 77.54  ? 13  C   B C4    1 
ATOM   1180 N  N4    . C   B 2 13  ? 23.629  -13.567 -2.000  1.00 77.52  ? 13  C   B N4    1 
ATOM   1181 C  C5    . C   B 2 13  ? 23.123  -15.723 -2.902  1.00 79.78  ? 13  C   B C5    1 
ATOM   1182 C  C6    . C   B 2 13  ? 22.522  -16.405 -3.885  1.00 80.39  ? 13  C   B C6    1 
ATOM   1183 P  P     . G   B 2 14  ? 24.920  -18.356 -8.593  1.00 100.75 ? 14  G   B P     1 
ATOM   1184 O  OP1   . G   B 2 14  ? 25.136  -18.989 -9.918  1.00 101.48 ? 14  G   B OP1   1 
ATOM   1185 O  OP2   . G   B 2 14  ? 25.703  -18.800 -7.414  1.00 103.39 ? 14  G   B OP2   1 
ATOM   1186 O  "O5'" . G   B 2 14  ? 25.188  -16.804 -8.792  1.00 94.27  ? 14  G   B "O5'" 1 
ATOM   1187 C  "C5'" . G   B 2 14  ? 24.610  -16.118 -9.888  1.00 96.95  ? 14  G   B "C5'" 1 
ATOM   1188 C  "C4'" . G   B 2 14  ? 24.704  -14.630 -9.702  1.00 96.60  ? 14  G   B "C4'" 1 
ATOM   1189 O  "O4'" . G   B 2 14  ? 24.012  -14.245 -8.487  1.00 92.21  ? 14  G   B "O4'" 1 
ATOM   1190 C  "C3'" . G   B 2 14  ? 26.106  -14.075 -9.510  1.00 99.50  ? 14  G   B "C3'" 1 
ATOM   1191 O  "O3'" . G   B 2 14  ? 26.822  -13.935 -10.720 1.00 104.22 ? 14  G   B "O3'" 1 
ATOM   1192 C  "C2'" . G   B 2 14  ? 25.837  -12.763 -8.799  1.00 97.22  ? 14  G   B "C2'" 1 
ATOM   1193 O  "O2'" . G   B 2 14  ? 25.351  -11.793 -9.717  1.00 90.99  ? 14  G   B "O2'" 1 
ATOM   1194 C  "C1'" . G   B 2 14  ? 24.697  -13.175 -7.867  1.00 97.74  ? 14  G   B "C1'" 1 
ATOM   1195 N  N9    . G   B 2 14  ? 25.229  -13.652 -6.579  1.00 90.83  ? 14  G   B N9    1 
ATOM   1196 C  C8    . G   B 2 14  ? 25.418  -14.958 -6.193  1.00 91.06  ? 14  G   B C8    1 
ATOM   1197 N  N7    . G   B 2 14  ? 25.928  -15.061 -4.996  1.00 93.49  ? 14  G   B N7    1 
ATOM   1198 C  C5    . G   B 2 14  ? 26.091  -13.746 -4.575  1.00 88.31  ? 14  G   B C5    1 
ATOM   1199 C  C6    . G   B 2 14  ? 26.599  -13.224 -3.359  1.00 88.74  ? 14  G   B C6    1 
ATOM   1200 O  O6    . G   B 2 14  ? 27.022  -13.838 -2.372  1.00 93.80  ? 14  G   B O6    1 
ATOM   1201 N  N1    . G   B 2 14  ? 26.584  -11.835 -3.357  1.00 83.18  ? 14  G   B N1    1 
ATOM   1202 C  C2    . G   B 2 14  ? 26.141  -11.045 -4.385  1.00 80.11  ? 14  G   B C2    1 
ATOM   1203 N  N2    . G   B 2 14  ? 26.213  -9.725  -4.178  1.00 78.40  ? 14  G   B N2    1 
ATOM   1204 N  N3    . G   B 2 14  ? 25.666  -11.512 -5.525  1.00 78.32  ? 14  G   B N3    1 
ATOM   1205 C  C4    . G   B 2 14  ? 25.669  -12.863 -5.545  1.00 83.84  ? 14  G   B C4    1 
ATOM   1206 P  P     . A   B 2 15  ? 28.077  -14.891 -11.011 1.00 110.81 ? 15  A   B P     1 
ATOM   1207 O  OP1   . A   B 2 15  ? 28.110  -15.178 -12.470 1.00 107.25 ? 15  A   B OP1   1 
ATOM   1208 O  OP2   . A   B 2 15  ? 28.029  -16.000 -10.018 1.00 110.56 ? 15  A   B OP2   1 
ATOM   1209 O  "O5'" . A   B 2 15  ? 29.330  -13.970 -10.681 1.00 102.25 ? 15  A   B "O5'" 1 
ATOM   1210 C  "C5'" . A   B 2 15  ? 30.034  -14.083 -9.453  1.00 103.41 ? 15  A   B "C5'" 1 
ATOM   1211 C  "C4'" . A   B 2 15  ? 30.910  -12.877 -9.255  1.00 99.65  ? 15  A   B "C4'" 1 
ATOM   1212 O  "O4'" . A   B 2 15  ? 31.087  -12.234 -10.534 1.00 97.67  ? 15  A   B "O4'" 1 
ATOM   1213 C  "C3'" . A   B 2 15  ? 30.333  -11.801 -8.351  1.00 98.75  ? 15  A   B "C3'" 1 
ATOM   1214 O  "O3'" . A   B 2 15  ? 30.713  -12.009 -7.010  1.00 93.17  ? 15  A   B "O3'" 1 
ATOM   1215 C  "C2'" . A   B 2 15  ? 30.888  -10.497 -8.919  1.00 101.31 ? 15  A   B "C2'" 1 
ATOM   1216 O  "O2'" . A   B 2 15  ? 32.153  -10.192 -8.350  1.00 102.88 ? 15  A   B "O2'" 1 
ATOM   1217 C  "C1'" . A   B 2 15  ? 31.086  -10.837 -10.391 1.00 96.82  ? 15  A   B "C1'" 1 
ATOM   1218 N  N9    . A   B 2 15  ? 30.060  -10.280 -11.289 1.00 100.06 ? 15  A   B N9    1 
ATOM   1219 C  C8    . A   B 2 15  ? 29.207  -11.003 -12.084 1.00 98.34  ? 15  A   B C8    1 
ATOM   1220 N  N7    . A   B 2 15  ? 28.421  -10.266 -12.828 1.00 99.30  ? 15  A   B N7    1 
ATOM   1221 C  C5    . A   B 2 15  ? 28.799  -8.968  -12.511 1.00 98.80  ? 15  A   B C5    1 
ATOM   1222 C  C6    . A   B 2 15  ? 28.340  -7.721  -12.967 1.00 97.80  ? 15  A   B C6    1 
ATOM   1223 N  N6    . A   B 2 15  ? 27.368  -7.581  -13.875 1.00 92.48  ? 15  A   B N6    1 
ATOM   1224 N  N1    . A   B 2 15  ? 28.923  -6.613  -12.455 1.00 97.56  ? 15  A   B N1    1 
ATOM   1225 C  C2    . A   B 2 15  ? 29.899  -6.761  -11.547 1.00 97.63  ? 15  A   B C2    1 
ATOM   1226 N  N3    . A   B 2 15  ? 30.419  -7.876  -11.037 1.00 94.63  ? 15  A   B N3    1 
ATOM   1227 C  C4    . A   B 2 15  ? 29.818  -8.957  -11.570 1.00 99.93  ? 15  A   B C4    1 
ATOM   1228 P  P     . A   B 2 16  ? 29.752  -11.535 -5.827  1.00 96.20  ? 16  A   B P     1 
ATOM   1229 O  OP1   . A   B 2 16  ? 30.494  -11.746 -4.559  1.00 96.45  ? 16  A   B OP1   1 
ATOM   1230 O  OP2   . A   B 2 16  ? 28.466  -12.243 -6.065  1.00 98.14  ? 16  A   B OP2   1 
ATOM   1231 O  "O5'" . A   B 2 16  ? 29.561  -9.964  -6.069  1.00 93.78  ? 16  A   B "O5'" 1 
ATOM   1232 C  "C5'" . A   B 2 16  ? 30.587  -9.025  -5.738  1.00 92.88  ? 16  A   B "C5'" 1 
ATOM   1233 C  "C4'" . A   B 2 16  ? 30.132  -7.591  -5.915  1.00 89.79  ? 16  A   B "C4'" 1 
ATOM   1234 O  "O4'" . A   B 2 16  ? 29.562  -7.444  -7.247  1.00 86.06  ? 16  A   B "O4'" 1 
ATOM   1235 C  "C3'" . A   B 2 16  ? 29.053  -7.123  -4.935  1.00 87.96  ? 16  A   B "C3'" 1 
ATOM   1236 O  "O3'" . A   B 2 16  ? 29.198  -5.729  -4.642  1.00 91.02  ? 16  A   B "O3'" 1 
ATOM   1237 C  "C2'" . A   B 2 16  ? 27.774  -7.355  -5.722  1.00 93.06  ? 16  A   B "C2'" 1 
ATOM   1238 O  "O2'" . A   B 2 16  ? 26.675  -6.573  -5.312  1.00 88.46  ? 16  A   B "O2'" 1 
ATOM   1239 C  "C1'" . A   B 2 16  ? 28.214  -7.027  -7.148  1.00 88.50  ? 16  A   B "C1'" 1 
ATOM   1240 N  N9    . A   B 2 16  ? 27.424  -7.746  -8.150  1.00 88.23  ? 16  A   B N9    1 
ATOM   1241 C  C8    . A   B 2 16  ? 27.160  -9.093  -8.188  1.00 89.00  ? 16  A   B C8    1 
ATOM   1242 N  N7    . A   B 2 16  ? 26.393  -9.458  -9.184  1.00 88.56  ? 16  A   B N7    1 
ATOM   1243 C  C5    . A   B 2 16  ? 26.117  -8.268  -9.839  1.00 88.23  ? 16  A   B C5    1 
ATOM   1244 C  C6    . A   B 2 16  ? 25.348  -7.976  -10.980 1.00 89.71  ? 16  A   B C6    1 
ATOM   1245 N  N6    . A   B 2 16  ? 24.688  -8.898  -11.691 1.00 82.40  ? 16  A   B N6    1 
ATOM   1246 N  N1    . A   B 2 16  ? 25.279  -6.683  -11.368 1.00 92.20  ? 16  A   B N1    1 
ATOM   1247 C  C2    . A   B 2 16  ? 25.940  -5.760  -10.654 1.00 88.60  ? 16  A   B C2    1 
ATOM   1248 N  N3    . A   B 2 16  ? 26.691  -5.910  -9.565  1.00 86.44  ? 16  A   B N3    1 
ATOM   1249 C  C4    . A   B 2 16  ? 26.740  -7.203  -9.208  1.00 88.01  ? 16  A   B C4    1 
ATOM   1250 P  P     . A   B 2 17  ? 28.353  -5.041  -3.446  1.00 91.02  ? 17  A   B P     1 
ATOM   1251 O  OP1   . A   B 2 17  ? 29.214  -4.041  -2.758  1.00 90.81  ? 17  A   B OP1   1 
ATOM   1252 O  OP2   . A   B 2 17  ? 27.695  -6.102  -2.646  1.00 76.65  ? 17  A   B OP2   1 
ATOM   1253 O  "O5'" . A   B 2 17  ? 27.182  -4.264  -4.200  1.00 93.70  ? 17  A   B "O5'" 1 
ATOM   1254 C  "C5'" . A   B 2 17  ? 27.420  -3.609  -5.438  1.00 86.74  ? 17  A   B "C5'" 1 
ATOM   1255 C  "C4'" . A   B 2 17  ? 26.166  -3.004  -6.030  1.00 81.15  ? 17  A   B "C4'" 1 
ATOM   1256 O  "O4'" . A   B 2 17  ? 25.819  -3.660  -7.271  1.00 83.95  ? 17  A   B "O4'" 1 
ATOM   1257 C  "C3'" . A   B 2 17  ? 24.880  -3.075  -5.223  1.00 74.03  ? 17  A   B "C3'" 1 
ATOM   1258 O  "O3'" . A   B 2 17  ? 24.843  -2.126  -4.169  1.00 72.63  ? 17  A   B "O3'" 1 
ATOM   1259 C  "C2'" . A   B 2 17  ? 23.810  -2.826  -6.289  1.00 76.92  ? 17  A   B "C2'" 1 
ATOM   1260 O  "O2'" . A   B 2 17  ? 23.643  -1.432  -6.508  1.00 81.56  ? 17  A   B "O2'" 1 
ATOM   1261 C  "C1'" . A   B 2 17  ? 24.453  -3.432  -7.544  1.00 80.33  ? 17  A   B "C1'" 1 
ATOM   1262 N  N9    . A   B 2 17  ? 23.800  -4.660  -8.050  1.00 85.77  ? 17  A   B N9    1 
ATOM   1263 C  C8    . A   B 2 17  ? 23.007  -4.709  -9.176  1.00 91.04  ? 17  A   B C8    1 
ATOM   1264 N  N7    . A   B 2 17  ? 22.534  -5.895  -9.472  1.00 85.23  ? 17  A   B N7    1 
ATOM   1265 C  C5    . A   B 2 17  ? 23.053  -6.696  -8.468  1.00 81.78  ? 17  A   B C5    1 
ATOM   1266 C  C6    . A   B 2 17  ? 22.915  -8.074  -8.219  1.00 81.12  ? 17  A   B C6    1 
ATOM   1267 N  N6    . A   B 2 17  ? 22.194  -8.896  -8.983  1.00 84.03  ? 17  A   B N6    1 
ATOM   1268 N  N1    . A   B 2 17  ? 23.553  -8.581  -7.144  1.00 80.11  ? 17  A   B N1    1 
ATOM   1269 C  C2    . A   B 2 17  ? 24.270  -7.741  -6.389  1.00 82.59  ? 17  A   B C2    1 
ATOM   1270 N  N3    . A   B 2 17  ? 24.480  -6.428  -6.509  1.00 81.02  ? 17  A   B N3    1 
ATOM   1271 C  C4    . A   B 2 17  ? 23.836  -5.955  -7.587  1.00 83.11  ? 17  A   B C4    1 
ATOM   1272 P  P     . G   B 2 18  ? 23.778  -2.271  -2.973  1.00 77.93  ? 18  G   B P     1 
ATOM   1273 O  OP1   . G   B 2 18  ? 23.955  -1.106  -2.070  1.00 69.91  ? 18  G   B OP1   1 
ATOM   1274 O  OP2   . G   B 2 18  ? 23.895  -3.646  -2.418  1.00 81.52  ? 18  G   B OP2   1 
ATOM   1275 O  "O5'" . G   B 2 18  ? 22.361  -2.155  -3.699  1.00 71.20  ? 18  G   B "O5'" 1 
ATOM   1276 C  "C5'" . G   B 2 18  ? 21.246  -2.922  -3.263  1.00 73.27  ? 18  G   B "C5'" 1 
ATOM   1277 C  "C4'" . G   B 2 18  ? 20.675  -3.777  -4.368  1.00 71.35  ? 18  G   B "C4'" 1 
ATOM   1278 O  "O4'" . G   B 2 18  ? 21.723  -4.612  -4.918  1.00 73.23  ? 18  G   B "O4'" 1 
ATOM   1279 C  "C3'" . G   B 2 18  ? 19.592  -4.760  -3.937  1.00 73.62  ? 18  G   B "C3'" 1 
ATOM   1280 O  "O3'" . G   B 2 18  ? 18.302  -4.177  -3.910  1.00 76.18  ? 18  G   B "O3'" 1 
ATOM   1281 C  "C2'" . G   B 2 18  ? 19.719  -5.890  -4.949  1.00 73.45  ? 18  G   B "C2'" 1 
ATOM   1282 O  "O2'" . G   B 2 18  ? 19.044  -5.567  -6.156  1.00 65.77  ? 18  G   B "O2'" 1 
ATOM   1283 C  "C1'" . G   B 2 18  ? 21.223  -5.898  -5.212  1.00 76.07  ? 18  G   B "C1'" 1 
ATOM   1284 N  N9    . G   B 2 18  ? 21.943  -6.869  -4.365  1.00 72.46  ? 18  G   B N9    1 
ATOM   1285 C  C8    . G   B 2 18  ? 22.917  -6.549  -3.449  1.00 71.47  ? 18  G   B C8    1 
ATOM   1286 N  N7    . G   B 2 18  ? 23.406  -7.586  -2.833  1.00 73.13  ? 18  G   B N7    1 
ATOM   1287 C  C5    . G   B 2 18  ? 22.722  -8.664  -3.383  1.00 71.94  ? 18  G   B C5    1 
ATOM   1288 C  C6    . G   B 2 18  ? 22.836  -10.053 -3.114  1.00 71.42  ? 18  G   B C6    1 
ATOM   1289 O  O6    . G   B 2 18  ? 23.583  -10.622 -2.309  1.00 74.69  ? 18  G   B O6    1 
ATOM   1290 N  N1    . G   B 2 18  ? 21.967  -10.808 -3.893  1.00 65.99  ? 18  G   B N1    1 
ATOM   1291 C  C2    . G   B 2 18  ? 21.096  -10.294 -4.819  1.00 71.74  ? 18  G   B C2    1 
ATOM   1292 N  N2    . G   B 2 18  ? 20.338  -11.192 -5.465  1.00 75.48  ? 18  G   B N2    1 
ATOM   1293 N  N3    . G   B 2 18  ? 20.977  -9.000  -5.086  1.00 74.14  ? 18  G   B N3    1 
ATOM   1294 C  C4    . G   B 2 18  ? 21.816  -8.244  -4.337  1.00 72.35  ? 18  G   B C4    1 
ATOM   1295 P  P     . U   B 2 19  ? 17.246  -4.617  -2.785  1.00 79.77  ? 19  U   B P     1 
ATOM   1296 O  OP1   . U   B 2 19  ? 16.093  -3.681  -2.808  1.00 78.86  ? 19  U   B OP1   1 
ATOM   1297 O  OP2   . U   B 2 19  ? 18.019  -4.847  -1.538  1.00 80.21  ? 19  U   B OP2   1 
ATOM   1298 O  "O5'" . U   B 2 19  ? 16.720  -6.030  -3.288  1.00 70.36  ? 19  U   B "O5'" 1 
ATOM   1299 C  "C5'" . U   B 2 19  ? 15.927  -6.145  -4.459  1.00 67.91  ? 19  U   B "C5'" 1 
ATOM   1300 C  "C4'" . U   B 2 19  ? 15.575  -7.585  -4.719  1.00 68.68  ? 19  U   B "C4'" 1 
ATOM   1301 O  "O4'" . U   B 2 19  ? 16.784  -8.337  -5.006  1.00 74.51  ? 19  U   B "O4'" 1 
ATOM   1302 C  "C3'" . U   B 2 19  ? 14.947  -8.328  -3.551  1.00 66.64  ? 19  U   B "C3'" 1 
ATOM   1303 O  "O3'" . U   B 2 19  ? 13.555  -8.078  -3.430  1.00 61.59  ? 19  U   B "O3'" 1 
ATOM   1304 C  "C2'" . U   B 2 19  ? 15.287  -9.780  -3.865  1.00 66.05  ? 19  U   B "C2'" 1 
ATOM   1305 O  "O2'" . U   B 2 19  ? 14.420  -10.278 -4.872  1.00 72.76  ? 19  U   B "O2'" 1 
ATOM   1306 C  "C1'" . U   B 2 19  ? 16.682  -9.642  -4.473  1.00 64.68  ? 19  U   B "C1'" 1 
ATOM   1307 N  N1    . U   B 2 19  ? 17.770  -9.830  -3.483  1.00 68.69  ? 19  U   B N1    1 
ATOM   1308 C  C2    . U   B 2 19  ? 18.084  -11.098 -3.010  1.00 70.54  ? 19  U   B C2    1 
ATOM   1309 O  O2    . U   B 2 19  ? 17.499  -12.114 -3.347  1.00 70.38  ? 19  U   B O2    1 
ATOM   1310 N  N3    . U   B 2 19  ? 19.118  -11.137 -2.104  1.00 69.58  ? 19  U   B N3    1 
ATOM   1311 C  C4    . U   B 2 19  ? 19.860  -10.066 -1.640  1.00 71.83  ? 19  U   B C4    1 
ATOM   1312 O  O4    . U   B 2 19  ? 20.767  -10.240 -0.826  1.00 76.36  ? 19  U   B O4    1 
ATOM   1313 C  C5    . U   B 2 19  ? 19.481  -8.800  -2.180  1.00 69.89  ? 19  U   B C5    1 
ATOM   1314 C  C6    . U   B 2 19  ? 18.483  -8.733  -3.061  1.00 70.32  ? 19  U   B C6    1 
ATOM   1315 P  P     . U   B 2 20  ? 12.848  -8.018  -1.987  1.00 71.67  ? 20  U   B P     1 
ATOM   1316 O  OP1   . U   B 2 20  ? 11.408  -7.769  -2.254  1.00 61.81  ? 20  U   B OP1   1 
ATOM   1317 O  OP2   . U   B 2 20  ? 13.613  -7.129  -1.057  1.00 72.76  ? 20  U   B OP2   1 
ATOM   1318 O  "O5'" . U   B 2 20  ? 12.957  -9.514  -1.459  1.00 66.64  ? 20  U   B "O5'" 1 
ATOM   1319 C  "C5'" . U   B 2 20  ? 12.288  -10.563 -2.137  1.00 66.42  ? 20  U   B "C5'" 1 
ATOM   1320 C  "C4'" . U   B 2 20  ? 12.752  -11.914 -1.657  1.00 71.68  ? 20  U   B "C4'" 1 
ATOM   1321 O  "O4'" . U   B 2 20  ? 14.183  -12.040 -1.812  1.00 68.90  ? 20  U   B "O4'" 1 
ATOM   1322 C  "C3'" . U   B 2 20  ? 12.517  -12.215 -0.190  1.00 71.53  ? 20  U   B "C3'" 1 
ATOM   1323 O  "O3'" . U   B 2 20  ? 11.189  -12.625 0.053   1.00 81.15  ? 20  U   B "O3'" 1 
ATOM   1324 C  "C2'" . U   B 2 20  ? 13.547  -13.298 0.110   1.00 69.45  ? 20  U   B "C2'" 1 
ATOM   1325 O  "O2'" . U   B 2 20  ? 13.058  -14.574 -0.274  1.00 71.38  ? 20  U   B "O2'" 1 
ATOM   1326 C  "C1'" . U   B 2 20  ? 14.693  -12.914 -0.827  1.00 69.72  ? 20  U   B "C1'" 1 
ATOM   1327 N  N1    . U   B 2 20  ? 15.831  -12.264 -0.138  1.00 74.61  ? 20  U   B N1    1 
ATOM   1328 C  C2    . U   B 2 20  ? 16.662  -13.063 0.629   1.00 73.31  ? 20  U   B C2    1 
ATOM   1329 O  O2    . U   B 2 20  ? 16.484  -14.257 0.795   1.00 73.45  ? 20  U   B O2    1 
ATOM   1330 N  N3    . U   B 2 20  ? 17.716  -12.411 1.219   1.00 75.13  ? 20  U   B N3    1 
ATOM   1331 C  C4    . U   B 2 20  ? 18.024  -11.067 1.111   1.00 76.44  ? 20  U   B C4    1 
ATOM   1332 O  O4    . U   B 2 20  ? 19.010  -10.617 1.703   1.00 77.51  ? 20  U   B O4    1 
ATOM   1333 C  C5    . U   B 2 20  ? 17.125  -10.313 0.289   1.00 72.69  ? 20  U   B C5    1 
ATOM   1334 C  C6    . U   B 2 20  ? 16.089  -10.921 -0.295  1.00 72.39  ? 20  U   B C6    1 
ATOM   1335 P  P     . C   B 2 21  ? 10.556  -12.438 1.510   1.00 92.49  ? 21  C   B P     1 
ATOM   1336 O  OP1   . C   B 2 21  ? 9.226   -13.107 1.544   1.00 90.28  ? 21  C   B OP1   1 
ATOM   1337 O  OP2   . C   B 2 21  ? 10.710  -11.011 1.890   1.00 79.58  ? 21  C   B OP2   1 
ATOM   1338 O  "O5'" . C   B 2 21  ? 11.525  -13.287 2.435   1.00 77.72  ? 21  C   B "O5'" 1 
ATOM   1339 C  "C5'" . C   B 2 21  ? 11.025  -13.904 3.602   1.00 77.52  ? 21  C   B "C5'" 1 
ATOM   1340 C  "C4'" . C   B 2 21  ? 11.861  -15.086 4.009   1.00 74.85  ? 21  C   B "C4'" 1 
ATOM   1341 O  "O4'" . C   B 2 21  ? 13.112  -15.110 3.273   1.00 72.25  ? 21  C   B "O4'" 1 
ATOM   1342 C  "C3'" . C   B 2 21  ? 12.286  -15.084 5.461   1.00 66.03  ? 21  C   B "C3'" 1 
ATOM   1343 O  "O3'" . C   B 2 21  ? 11.261  -15.532 6.319   1.00 56.80  ? 21  C   B "O3'" 1 
ATOM   1344 C  "C2'" . C   B 2 21  ? 13.526  -15.961 5.451   1.00 64.40  ? 21  C   B "C2'" 1 
ATOM   1345 O  "O2'" . C   B 2 21  ? 13.159  -17.329 5.392   1.00 67.79  ? 21  C   B "O2'" 1 
ATOM   1346 C  "C1'" . C   B 2 21  ? 14.154  -15.569 4.111   1.00 69.41  ? 21  C   B "C1'" 1 
ATOM   1347 N  N1    . C   B 2 21  ? 15.148  -14.477 4.247   1.00 72.93  ? 21  C   B N1    1 
ATOM   1348 C  C2    . C   B 2 21  ? 16.340  -14.662 4.968   1.00 69.21  ? 21  C   B C2    1 
ATOM   1349 O  O2    . C   B 2 21  ? 16.559  -15.758 5.503   1.00 63.81  ? 21  C   B O2    1 
ATOM   1350 N  N3    . C   B 2 21  ? 17.217  -13.630 5.062   1.00 68.50  ? 21  C   B N3    1 
ATOM   1351 C  C4    . C   B 2 21  ? 16.952  -12.459 4.476   1.00 69.57  ? 21  C   B C4    1 
ATOM   1352 N  N4    . C   B 2 21  ? 17.841  -11.471 4.593   1.00 69.46  ? 21  C   B N4    1 
ATOM   1353 C  C5    . C   B 2 21  ? 15.757  -12.249 3.733   1.00 71.68  ? 21  C   B C5    1 
ATOM   1354 C  C6    . C   B 2 21  ? 14.899  -13.273 3.646   1.00 71.72  ? 21  C   B C6    1 
ATOM   1355 P  P     . C   B 2 22  ? 10.898  -14.669 7.618   1.00 76.57  ? 22  C   B P     1 
ATOM   1356 O  OP1   . C   B 2 22  ? 9.617   -15.203 8.157   1.00 76.20  ? 22  C   B OP1   1 
ATOM   1357 O  OP2   . C   B 2 22  ? 11.000  -13.222 7.273   1.00 69.47  ? 22  C   B OP2   1 
ATOM   1358 O  "O5'" . C   B 2 22  ? 12.075  -15.045 8.624   1.00 73.87  ? 22  C   B "O5'" 1 
ATOM   1359 C  "C5'" . C   B 2 22  ? 12.406  -16.407 8.868   1.00 69.29  ? 22  C   B "C5'" 1 
ATOM   1360 C  "C4'" . C   B 2 22  ? 13.660  -16.541 9.696   1.00 65.28  ? 22  C   B "C4'" 1 
ATOM   1361 O  "O4'" . C   B 2 22  ? 14.827  -16.220 8.900   1.00 62.97  ? 22  C   B "O4'" 1 
ATOM   1362 C  "C3'" . C   B 2 22  ? 13.764  -15.610 10.888  1.00 62.92  ? 22  C   B "C3'" 1 
ATOM   1363 O  "O3'" . C   B 2 22  ? 13.010  -16.062 11.992  1.00 63.62  ? 22  C   B "O3'" 1 
ATOM   1364 C  "C2'" . C   B 2 22  ? 15.264  -15.561 11.142  1.00 64.24  ? 22  C   B "C2'" 1 
ATOM   1365 O  "O2'" . C   B 2 22  ? 15.698  -16.730 11.824  1.00 66.64  ? 22  C   B "O2'" 1 
ATOM   1366 C  "C1'" . C   B 2 22  ? 15.807  -15.609 9.713   1.00 64.64  ? 22  C   B "C1'" 1 
ATOM   1367 N  N1    . C   B 2 22  ? 16.091  -14.262 9.168   1.00 65.59  ? 22  C   B N1    1 
ATOM   1368 C  C2    . C   B 2 22  ? 17.277  -13.619 9.537   1.00 65.43  ? 22  C   B C2    1 
ATOM   1369 O  O2    . C   B 2 22  ? 18.053  -14.186 10.321  1.00 65.14  ? 22  C   B O2    1 
ATOM   1370 N  N3    . C   B 2 22  ? 17.550  -12.395 9.032   1.00 63.67  ? 22  C   B N3    1 
ATOM   1371 C  C4    . C   B 2 22  ? 16.694  -11.819 8.187   1.00 67.09  ? 22  C   B C4    1 
ATOM   1372 N  N4    . C   B 2 22  ? 17.006  -10.610 7.714   1.00 75.06  ? 22  C   B N4    1 
ATOM   1373 C  C5    . C   B 2 22  ? 15.482  -12.454 7.789   1.00 67.11  ? 22  C   B C5    1 
ATOM   1374 C  C6    . C   B 2 22  ? 15.222  -13.665 8.298   1.00 64.37  ? 22  C   B C6    1 
ATOM   1375 P  P     . A   B 2 23  ? 12.103  -15.022 12.807  1.00 59.22  ? 23  A   B P     1 
ATOM   1376 O  OP1   . A   B 2 23  ? 10.682  -15.340 12.523  1.00 57.93  ? 23  A   B OP1   1 
ATOM   1377 O  OP2   . A   B 2 23  ? 12.635  -13.663 12.528  1.00 66.21  ? 23  A   B OP2   1 
ATOM   1378 O  "O5'" . A   B 2 23  ? 12.429  -15.354 14.328  1.00 60.79  ? 23  A   B "O5'" 1 
ATOM   1379 C  "C5'" . A   B 2 23  ? 13.758  -15.660 14.727  1.00 57.07  ? 23  A   B "C5'" 1 
ATOM   1380 C  "C4'" . A   B 2 23  ? 13.790  -16.292 16.091  1.00 52.12  ? 23  A   B "C4'" 1 
ATOM   1381 O  "O4'" . A   B 2 23  ? 15.124  -16.815 16.338  1.00 57.38  ? 23  A   B "O4'" 1 
ATOM   1382 C  "C3'" . A   B 2 23  ? 13.496  -15.335 17.240  1.00 51.48  ? 23  A   B "C3'" 1 
ATOM   1383 O  "O3'" . A   B 2 23  ? 12.878  -16.064 18.299  1.00 51.05  ? 23  A   B "O3'" 1 
ATOM   1384 C  "C2'" . A   B 2 23  ? 14.893  -14.908 17.669  1.00 50.35  ? 23  A   B "C2'" 1 
ATOM   1385 O  "O2'" . A   B 2 23  ? 14.982  -14.424 18.991  1.00 60.04  ? 23  A   B "O2'" 1 
ATOM   1386 C  "C1'" . A   B 2 23  ? 15.656  -16.214 17.502  1.00 53.85  ? 23  A   B "C1'" 1 
ATOM   1387 N  N9    . A   B 2 23  ? 17.098  -16.051 17.329  1.00 52.69  ? 23  A   B N9    1 
ATOM   1388 C  C8    . A   B 2 23  ? 18.087  -16.380 18.220  1.00 53.22  ? 23  A   B C8    1 
ATOM   1389 N  N7    . A   B 2 23  ? 19.286  -16.106 17.767  1.00 55.52  ? 23  A   B N7    1 
ATOM   1390 C  C5    . A   B 2 23  ? 19.067  -15.561 16.515  1.00 44.86  ? 23  A   B C5    1 
ATOM   1391 C  C6    . A   B 2 23  ? 19.939  -15.073 15.544  1.00 41.82  ? 23  A   B C6    1 
ATOM   1392 N  N6    . A   B 2 23  ? 21.264  -15.050 15.689  1.00 47.95  ? 23  A   B N6    1 
ATOM   1393 N  N1    . A   B 2 23  ? 19.396  -14.606 14.406  1.00 50.11  ? 23  A   B N1    1 
ATOM   1394 C  C2    . A   B 2 23  ? 18.067  -14.625 14.257  1.00 53.28  ? 23  A   B C2    1 
ATOM   1395 N  N3    . A   B 2 23  ? 17.146  -15.064 15.106  1.00 52.91  ? 23  A   B N3    1 
ATOM   1396 C  C4    . A   B 2 23  ? 17.724  -15.519 16.229  1.00 50.95  ? 23  A   B C4    1 
ATOM   1397 P  P     . U   B 2 24  ? 11.531  -15.522 18.983  1.00 51.31  ? 24  U   B P     1 
ATOM   1398 O  OP1   . U   B 2 24  ? 11.574  -14.039 19.001  1.00 55.05  ? 24  U   B OP1   1 
ATOM   1399 O  OP2   . U   B 2 24  ? 11.317  -16.266 20.249  1.00 54.95  ? 24  U   B OP2   1 
ATOM   1400 O  "O5'" . U   B 2 24  ? 10.392  -15.961 17.967  1.00 47.63  ? 24  U   B "O5'" 1 
ATOM   1401 C  "C5'" . U   B 2 24  ? 10.090  -17.333 17.764  1.00 53.80  ? 24  U   B "C5'" 1 
ATOM   1402 C  "C4'" . U   B 2 24  ? 8.992   -17.505 16.749  1.00 57.50  ? 24  U   B "C4'" 1 
ATOM   1403 O  "O4'" . U   B 2 24  ? 7.870   -16.656 17.108  1.00 60.73  ? 24  U   B "O4'" 1 
ATOM   1404 C  "C3'" . U   B 2 24  ? 9.371   -17.136 15.320  1.00 58.00  ? 24  U   B "C3'" 1 
ATOM   1405 O  "O3'" . U   B 2 24  ? 8.714   -18.024 14.420  1.00 61.81  ? 24  U   B "O3'" 1 
ATOM   1406 C  "C2'" . U   B 2 24  ? 8.796   -15.730 15.159  1.00 54.82  ? 24  U   B "C2'" 1 
ATOM   1407 O  "O2'" . U   B 2 24  ? 8.457   -15.401 13.830  1.00 61.45  ? 24  U   B "O2'" 1 
ATOM   1408 C  "C1'" . U   B 2 24  ? 7.552   -15.792 16.037  1.00 53.34  ? 24  U   B "C1'" 1 
ATOM   1409 N  N1    . U   B 2 24  ? 7.159   -14.501 16.618  1.00 56.93  ? 24  U   B N1    1 
ATOM   1410 C  C2    . U   B 2 24  ? 6.015   -13.901 16.140  1.00 61.72  ? 24  U   B C2    1 
ATOM   1411 O  O2    . U   B 2 24  ? 5.336   -14.386 15.257  1.00 70.74  ? 24  U   B O2    1 
ATOM   1412 N  N3    . U   B 2 24  ? 5.694   -12.709 16.735  1.00 58.63  ? 24  U   B N3    1 
ATOM   1413 C  C4    . U   B 2 24  ? 6.387   -12.067 17.741  1.00 60.62  ? 24  U   B C4    1 
ATOM   1414 O  O4    . U   B 2 24  ? 5.967   -10.993 18.173  1.00 67.49  ? 24  U   B O4    1 
ATOM   1415 C  C5    . U   B 2 24  ? 7.560   -12.752 18.189  1.00 52.99  ? 24  U   B C5    1 
ATOM   1416 C  C6    . U   B 2 24  ? 7.893   -13.918 17.625  1.00 57.02  ? 24  U   B C6    1 
ATOM   1417 P  P     . G   B 2 25  ? 9.292   -19.502 14.164  1.00 59.95  ? 25  G   B P     1 
ATOM   1418 O  OP1   . G   B 2 25  ? 8.935   -19.879 12.768  1.00 66.36  ? 25  G   B OP1   1 
ATOM   1419 O  OP2   . G   B 2 25  ? 8.894   -20.364 15.310  1.00 49.98  ? 25  G   B OP2   1 
ATOM   1420 O  "O5'" . G   B 2 25  ? 10.871  -19.307 14.187  1.00 52.00  ? 25  G   B "O5'" 1 
ATOM   1421 C  "C5'" . G   B 2 25  ? 11.560  -18.857 13.025  1.00 51.52  ? 25  G   B "C5'" 1 
ATOM   1422 C  "C4'" . G   B 2 25  ? 12.949  -19.437 12.945  1.00 56.34  ? 25  G   B "C4'" 1 
ATOM   1423 O  "O4'" . G   B 2 25  ? 13.668  -19.106 14.168  1.00 60.33  ? 25  G   B "O4'" 1 
ATOM   1424 C  "C3'" . G   B 2 25  ? 13.010  -20.960 12.810  1.00 57.05  ? 25  G   B "C3'" 1 
ATOM   1425 O  "O3'" . G   B 2 25  ? 14.120  -21.336 11.996  1.00 55.77  ? 25  G   B "O3'" 1 
ATOM   1426 C  "C2'" . G   B 2 25  ? 13.258  -21.413 14.242  1.00 58.47  ? 25  G   B "C2'" 1 
ATOM   1427 O  "O2'" . G   B 2 25  ? 13.869  -22.680 14.369  1.00 56.14  ? 25  G   B "O2'" 1 
ATOM   1428 C  "C1'" . G   B 2 25  ? 14.153  -20.293 14.763  1.00 62.17  ? 25  G   B "C1'" 1 
ATOM   1429 N  N9    . G   B 2 25  ? 14.120  -20.165 16.219  1.00 55.40  ? 25  G   B N9    1 
ATOM   1430 C  C8    . G   B 2 25  ? 13.009  -20.189 17.026  1.00 58.00  ? 25  G   B C8    1 
ATOM   1431 N  N7    . G   B 2 25  ? 13.296  -20.077 18.294  1.00 61.19  ? 25  G   B N7    1 
ATOM   1432 C  C5    . G   B 2 25  ? 14.683  -20.001 18.325  1.00 60.14  ? 25  G   B C5    1 
ATOM   1433 C  C6    . G   B 2 25  ? 15.575  -19.881 19.424  1.00 61.25  ? 25  G   B C6    1 
ATOM   1434 O  O6    . G   B 2 25  ? 15.295  -19.821 20.628  1.00 60.63  ? 25  G   B O6    1 
ATOM   1435 N  N1    . G   B 2 25  ? 16.904  -19.843 19.009  1.00 55.08  ? 25  G   B N1    1 
ATOM   1436 C  C2    . G   B 2 25  ? 17.317  -19.909 17.702  1.00 57.29  ? 25  G   B C2    1 
ATOM   1437 N  N2    . G   B 2 25  ? 18.640  -19.848 17.497  1.00 59.52  ? 25  G   B N2    1 
ATOM   1438 N  N3    . G   B 2 25  ? 16.497  -20.020 16.667  1.00 59.84  ? 25  G   B N3    1 
ATOM   1439 C  C4    . G   B 2 25  ? 15.205  -20.061 17.051  1.00 55.79  ? 25  G   B C4    1 
ATOM   1440 P  P     . A   B 2 26  ? 14.143  -22.779 11.284  1.00 65.16  ? 26  A   B P     1 
ATOM   1441 O  OP1   . A   B 2 26  ? 12.771  -23.344 11.360  1.00 59.22  ? 26  A   B OP1   1 
ATOM   1442 O  OP2   . A   B 2 26  ? 15.300  -23.547 11.822  1.00 62.37  ? 26  A   B OP2   1 
ATOM   1443 O  "O5'" . A   B 2 26  ? 14.429  -22.445 9.755   1.00 62.22  ? 26  A   B "O5'" 1 
ATOM   1444 C  "C5'" . A   B 2 26  ? 13.535  -21.626 9.018   1.00 67.36  ? 26  A   B "C5'" 1 
ATOM   1445 C  "C4'" . A   B 2 26  ? 14.263  -20.509 8.319   1.00 61.09  ? 26  A   B "C4'" 1 
ATOM   1446 O  "O4'" . A   B 2 26  ? 14.906  -19.657 9.303   1.00 60.41  ? 26  A   B "O4'" 1 
ATOM   1447 C  "C3'" . A   B 2 26  ? 15.391  -20.938 7.392   1.00 64.24  ? 26  A   B "C3'" 1 
ATOM   1448 O  "O3'" . A   B 2 26  ? 14.925  -21.293 6.099   1.00 76.72  ? 26  A   B "O3'" 1 
ATOM   1449 C  "C2'" . A   B 2 26  ? 16.294  -19.713 7.380   1.00 63.46  ? 26  A   B "C2'" 1 
ATOM   1450 O  "O2'" . A   B 2 26  ? 15.767  -18.723 6.511   1.00 65.88  ? 26  A   B "O2'" 1 
ATOM   1451 C  "C1'" . A   B 2 26  ? 16.153  -19.216 8.818   1.00 60.20  ? 26  A   B "C1'" 1 
ATOM   1452 N  N9    . A   B 2 26  ? 17.199  -19.763 9.696   1.00 54.58  ? 26  A   B N9    1 
ATOM   1453 C  C8    . A   B 2 26  ? 17.006  -20.499 10.836  1.00 58.14  ? 26  A   B C8    1 
ATOM   1454 N  N7    . A   B 2 26  ? 18.117  -20.859 11.429  1.00 54.60  ? 26  A   B N7    1 
ATOM   1455 C  C5    . A   B 2 26  ? 19.097  -20.319 10.617  1.00 53.19  ? 26  A   B C5    1 
ATOM   1456 C  C6    . A   B 2 26  ? 20.492  -20.347 10.717  1.00 57.94  ? 26  A   B C6    1 
ATOM   1457 N  N6    . A   B 2 26  ? 21.123  -20.972 11.713  1.00 54.92  ? 26  A   B N6    1 
ATOM   1458 N  N1    . A   B 2 26  ? 21.204  -19.709 9.755   1.00 63.99  ? 26  A   B N1    1 
ATOM   1459 C  C2    . A   B 2 26  ? 20.543  -19.084 8.769   1.00 56.82  ? 26  A   B C2    1 
ATOM   1460 N  N3    . A   B 2 26  ? 19.231  -18.988 8.572   1.00 52.19  ? 26  A   B N3    1 
ATOM   1461 C  C4    . A   B 2 26  ? 18.555  -19.635 9.543   1.00 53.59  ? 26  A   B C4    1 
ATOM   1462 P  P     . C   B 2 27  ? 15.325  -22.692 5.408   1.00 79.17  ? 27  C   B P     1 
ATOM   1463 O  OP1   . C   B 2 27  ? 14.918  -22.587 3.977   1.00 69.82  ? 27  C   B OP1   1 
ATOM   1464 O  OP2   . C   B 2 27  ? 14.783  -23.804 6.239   1.00 79.71  ? 27  C   B OP2   1 
ATOM   1465 O  "O5'" . C   B 2 27  ? 16.920  -22.736 5.475   1.00 70.80  ? 27  C   B "O5'" 1 
ATOM   1466 C  "C5'" . C   B 2 27  ? 17.711  -21.822 4.727   1.00 71.58  ? 27  C   B "C5'" 1 
ATOM   1467 C  "C4'" . C   B 2 27  ? 19.161  -21.856 5.149   1.00 70.44  ? 27  C   B "C4'" 1 
ATOM   1468 O  "O4'" . C   B 2 27  ? 19.292  -21.428 6.528   1.00 73.54  ? 27  C   B "O4'" 1 
ATOM   1469 C  "C3'" . C   B 2 27  ? 19.819  -23.220 5.122   1.00 76.11  ? 27  C   B "C3'" 1 
ATOM   1470 O  "O3'" . C   B 2 27  ? 20.241  -23.578 3.821   1.00 78.75  ? 27  C   B "O3'" 1 
ATOM   1471 C  "C2'" . C   B 2 27  ? 20.961  -23.071 6.122   1.00 74.39  ? 27  C   B "C2'" 1 
ATOM   1472 O  "O2'" . C   B 2 27  ? 22.069  -22.415 5.523   1.00 71.04  ? 27  C   B "O2'" 1 
ATOM   1473 C  "C1'" . C   B 2 27  ? 20.345  -22.127 7.156   1.00 63.69  ? 27  C   B "C1'" 1 
ATOM   1474 N  N1    . C   B 2 27  ? 19.792  -22.814 8.348   1.00 58.36  ? 27  C   B N1    1 
ATOM   1475 C  C2    . C   B 2 27  ? 20.617  -23.431 9.296   1.00 63.70  ? 27  C   B C2    1 
ATOM   1476 O  O2    . C   B 2 27  ? 21.844  -23.446 9.114   1.00 67.83  ? 27  C   B O2    1 
ATOM   1477 N  N3    . C   B 2 27  ? 20.055  -24.020 10.384  1.00 66.39  ? 27  C   B N3    1 
ATOM   1478 C  C4    . C   B 2 27  ? 18.728  -23.993 10.557  1.00 66.82  ? 27  C   B C4    1 
ATOM   1479 N  N4    . C   B 2 27  ? 18.197  -24.580 11.634  1.00 68.07  ? 27  C   B N4    1 
ATOM   1480 C  C5    . C   B 2 27  ? 17.870  -23.361 9.615   1.00 64.98  ? 27  C   B C5    1 
ATOM   1481 C  C6    . C   B 2 27  ? 18.441  -22.787 8.550   1.00 63.27  ? 27  C   B C6    1 
ATOM   1482 P  P     . G   B 2 28  ? 19.765  -24.973 3.200   1.00 89.52  ? 28  G   B P     1 
ATOM   1483 O  OP1   . G   B 2 28  ? 20.888  -25.482 2.372   1.00 103.27 ? 28  G   B OP1   1 
ATOM   1484 O  OP2   . G   B 2 28  ? 18.410  -24.817 2.612   1.00 87.40  ? 28  G   B OP2   1 
ATOM   1485 O  "O5'" . G   B 2 28  ? 19.649  -25.909 4.478   1.00 78.43  ? 28  G   B "O5'" 1 
ATOM   1486 C  "C5'" . G   B 2 28  ? 20.411  -27.100 4.552   1.00 90.36  ? 28  G   B "C5'" 1 
ATOM   1487 C  "C4'" . G   B 2 28  ? 21.483  -27.031 5.610   1.00 88.83  ? 28  G   B "C4'" 1 
ATOM   1488 O  "O4'" . G   B 2 28  ? 21.070  -26.150 6.685   1.00 77.98  ? 28  G   B "O4'" 1 
ATOM   1489 C  "C3'" . G   B 2 28  ? 21.777  -28.356 6.294   1.00 93.96  ? 28  G   B "C3'" 1 
ATOM   1490 O  "O3'" . G   B 2 28  ? 22.683  -29.150 5.551   1.00 96.59  ? 28  G   B "O3'" 1 
ATOM   1491 C  "C2'" . G   B 2 28  ? 22.290  -27.934 7.665   1.00 83.60  ? 28  G   B "C2'" 1 
ATOM   1492 O  "O2'" . G   B 2 28  ? 23.652  -27.543 7.590   1.00 76.31  ? 28  G   B "O2'" 1 
ATOM   1493 C  "C1'" . G   B 2 28  ? 21.448  -26.688 7.933   1.00 72.59  ? 28  G   B "C1'" 1 
ATOM   1494 N  N9    . G   B 2 28  ? 20.203  -26.961 8.678   1.00 72.57  ? 28  G   B N9    1 
ATOM   1495 C  C8    . G   B 2 28  ? 18.989  -26.423 8.319   1.00 74.26  ? 28  G   B C8    1 
ATOM   1496 N  N7    . G   B 2 28  ? 18.003  -26.755 9.100   1.00 73.58  ? 28  G   B N7    1 
ATOM   1497 C  C5    . G   B 2 28  ? 18.601  -27.566 10.048  1.00 72.67  ? 28  G   B C5    1 
ATOM   1498 C  C6    . G   B 2 28  ? 18.006  -28.216 11.159  1.00 77.04  ? 28  G   B C6    1 
ATOM   1499 O  O6    . G   B 2 28  ? 16.815  -28.188 11.498  1.00 74.53  ? 28  G   B O6    1 
ATOM   1500 N  N1    . G   B 2 28  ? 18.941  -28.948 11.885  1.00 81.42  ? 28  G   B N1    1 
ATOM   1501 C  C2    . G   B 2 28  ? 20.283  -29.037 11.578  1.00 82.37  ? 28  G   B C2    1 
ATOM   1502 N  N2    . G   B 2 28  ? 21.030  -29.797 12.396  1.00 78.70  ? 28  G   B N2    1 
ATOM   1503 N  N3    . G   B 2 28  ? 20.850  -28.420 10.541  1.00 74.49  ? 28  G   B N3    1 
ATOM   1504 C  C4    . G   B 2 28  ? 19.961  -27.699 9.820   1.00 71.97  ? 28  G   B C4    1 
ATOM   1505 P  P     . C   B 2 29  ? 22.135  -30.321 4.598   1.00 100.53 ? 29  C   B P     1 
ATOM   1506 O  OP1   . C   B 2 29  ? 22.970  -30.351 3.368   1.00 95.84  ? 29  C   B OP1   1 
ATOM   1507 O  OP2   . C   B 2 29  ? 20.662  -30.178 4.474   1.00 95.79  ? 29  C   B OP2   1 
ATOM   1508 O  "O5'" . C   B 2 29  ? 22.409  -31.636 5.449   1.00 95.67  ? 29  C   B "O5'" 1 
ATOM   1509 C  "C5'" . C   B 2 29  ? 23.589  -31.753 6.226   1.00 94.94  ? 29  C   B "C5'" 1 
ATOM   1510 C  "C4'" . C   B 2 29  ? 23.353  -32.567 7.473   1.00 97.39  ? 29  C   B "C4'" 1 
ATOM   1511 O  "O4'" . C   B 2 29  ? 22.797  -31.735 8.524   1.00 94.94  ? 29  C   B "O4'" 1 
ATOM   1512 C  "C3'" . C   B 2 29  ? 22.358  -33.707 7.351   1.00 101.34 ? 29  C   B "C3'" 1 
ATOM   1513 O  "O3'" . C   B 2 29  ? 22.904  -34.847 6.716   1.00 106.10 ? 29  C   B "O3'" 1 
ATOM   1514 C  "C2'" . C   B 2 29  ? 21.952  -33.938 8.801   1.00 97.65  ? 29  C   B "C2'" 1 
ATOM   1515 O  "O2'" . C   B 2 29  ? 22.958  -34.654 9.504   1.00 95.78  ? 29  C   B "O2'" 1 
ATOM   1516 C  "C1'" . C   B 2 29  ? 21.926  -32.504 9.331   1.00 87.49  ? 29  C   B "C1'" 1 
ATOM   1517 N  N1    . C   B 2 29  ? 20.576  -31.900 9.268   1.00 83.75  ? 29  C   B N1    1 
ATOM   1518 C  C2    . C   B 2 29  ? 19.584  -32.334 10.157  1.00 90.00  ? 29  C   B C2    1 
ATOM   1519 O  O2    . C   B 2 29  ? 19.862  -33.242 10.958  1.00 92.58  ? 29  C   B O2    1 
ATOM   1520 N  N3    . C   B 2 29  ? 18.353  -31.771 10.099  1.00 89.20  ? 29  C   B N3    1 
ATOM   1521 C  C4    . C   B 2 29  ? 18.106  -30.802 9.210   1.00 90.06  ? 29  C   B C4    1 
ATOM   1522 N  N4    . C   B 2 29  ? 16.882  -30.266 9.188   1.00 88.21  ? 29  C   B N4    1 
ATOM   1523 C  C5    . C   B 2 29  ? 19.105  -30.338 8.301   1.00 88.35  ? 29  C   B C5    1 
ATOM   1524 C  C6    . C   B 2 29  ? 20.315  -30.905 8.368   1.00 84.83  ? 29  C   B C6    1 
ATOM   1525 P  P     . A   B 2 30  ? 22.109  -35.569 5.521   1.00 111.67 ? 30  A   B P     1 
ATOM   1526 O  OP1   . A   B 2 30  ? 22.982  -35.596 4.318   1.00 112.33 ? 30  A   B OP1   1 
ATOM   1527 O  OP2   . A   B 2 30  ? 20.752  -34.979 5.416   1.00 105.43 ? 30  A   B OP2   1 
ATOM   1528 O  "O5'" . A   B 2 30  ? 21.941  -37.059 6.047   1.00 109.05 ? 30  A   B "O5'" 1 
ATOM   1529 C  "C5'" . A   B 2 30  ? 20.653  -37.590 6.290   1.00 108.95 ? 30  A   B "C5'" 1 
ATOM   1530 C  "C4'" . A   B 2 30  ? 20.440  -37.906 7.747   1.00 109.48 ? 30  A   B "C4'" 1 
ATOM   1531 O  "O4'" . A   B 2 30  ? 20.414  -36.680 8.528   1.00 97.30  ? 30  A   B "O4'" 1 
ATOM   1532 C  "C3'" . A   B 2 30  ? 19.114  -38.579 8.053   1.00 115.33 ? 30  A   B "C3'" 1 
ATOM   1533 O  "O3'" . A   B 2 30  ? 19.164  -39.977 7.829   1.00 115.55 ? 30  A   B "O3'" 1 
ATOM   1534 C  "C2'" . A   B 2 30  ? 18.852  -38.178 9.501   1.00 114.26 ? 30  A   B "C2'" 1 
ATOM   1535 O  "O2'" . A   B 2 30  ? 19.616  -38.975 10.394  1.00 116.86 ? 30  A   B "O2'" 1 
ATOM   1536 C  "C1'" . A   B 2 30  ? 19.415  -36.757 9.524   1.00 101.62 ? 30  A   B "C1'" 1 
ATOM   1537 N  N9    . A   B 2 30  ? 18.397  -35.730 9.217   1.00 100.17 ? 30  A   B N9    1 
ATOM   1538 C  C8    . A   B 2 30  ? 18.606  -34.689 8.349   1.00 101.00 ? 30  A   B C8    1 
ATOM   1539 N  N7    . A   B 2 30  ? 17.592  -33.877 8.212   1.00 99.11  ? 30  A   B N7    1 
ATOM   1540 C  C5    . A   B 2 30  ? 16.634  -34.416 9.051   1.00 100.68 ? 30  A   B C5    1 
ATOM   1541 C  C6    . A   B 2 30  ? 15.326  -33.997 9.337   1.00 101.05 ? 30  A   B C6    1 
ATOM   1542 N  N6    . A   B 2 30  ? 14.766  -32.915 8.793   1.00 104.84 ? 30  A   B N6    1 
ATOM   1543 N  N1    . A   B 2 30  ? 14.608  -34.732 10.208  1.00 101.53 ? 30  A   B N1    1 
ATOM   1544 C  C2    . A   B 2 30  ? 15.179  -35.818 10.753  1.00 103.31 ? 30  A   B C2    1 
ATOM   1545 N  N3    . A   B 2 30  ? 16.408  -36.310 10.562  1.00 103.60 ? 30  A   B N3    1 
ATOM   1546 C  C4    . A   B 2 30  ? 17.105  -35.556 9.688   1.00 102.20 ? 30  A   B C4    1 
ATOM   1547 P  P     . U   B 2 31  ? 18.618  -40.603 6.451   1.00 121.61 ? 31  U   B P     1 
ATOM   1548 O  OP1   . U   B 2 31  ? 19.608  -41.601 5.968   1.00 123.66 ? 31  U   B OP1   1 
ATOM   1549 O  OP2   . U   B 2 31  ? 18.214  -39.508 5.533   1.00 117.07 ? 31  U   B OP2   1 
ATOM   1550 O  "O5'" . U   B 2 31  ? 17.303  -41.374 6.904   1.00 125.39 ? 31  U   B "O5'" 1 
ATOM   1551 C  "C5'" . U   B 2 31  ? 17.281  -42.102 8.123   1.00 126.37 ? 31  U   B "C5'" 1 
ATOM   1552 C  "C4'" . U   B 2 31  ? 15.940  -42.007 8.805   1.00 126.69 ? 31  U   B "C4'" 1 
ATOM   1553 O  "O4'" . U   B 2 31  ? 15.813  -40.735 9.497   1.00 120.71 ? 31  U   B "O4'" 1 
ATOM   1554 C  "C3'" . U   B 2 31  ? 14.727  -42.045 7.892   1.00 133.11 ? 31  U   B "C3'" 1 
ATOM   1555 O  "O3'" . U   B 2 31  ? 14.398  -43.349 7.444   1.00 134.26 ? 31  U   B "O3'" 1 
ATOM   1556 C  "C2'" . U   B 2 31  ? 13.654  -41.389 8.751   1.00 131.18 ? 31  U   B "C2'" 1 
ATOM   1557 O  "O2'" . U   B 2 31  ? 13.157  -42.294 9.726   1.00 133.53 ? 31  U   B "O2'" 1 
ATOM   1558 C  "C1'" . U   B 2 31  ? 14.465  -40.305 9.463   1.00 122.50 ? 31  U   B "C1'" 1 
ATOM   1559 N  N1    . U   B 2 31  ? 14.392  -39.008 8.749   1.00 121.52 ? 31  U   B N1    1 
ATOM   1560 C  C2    . U   B 2 31  ? 13.193  -38.313 8.775   1.00 120.86 ? 31  U   B C2    1 
ATOM   1561 O  O2    . U   B 2 31  ? 12.198  -38.710 9.356   1.00 121.52 ? 31  U   B O2    1 
ATOM   1562 N  N3    . U   B 2 31  ? 13.188  -37.123 8.088   1.00 118.16 ? 31  U   B N3    1 
ATOM   1563 C  C4    . U   B 2 31  ? 14.238  -36.560 7.391   1.00 117.14 ? 31  U   B C4    1 
ATOM   1564 O  O4    . U   B 2 31  ? 14.088  -35.476 6.819   1.00 116.32 ? 31  U   B O4    1 
ATOM   1565 C  C5    . U   B 2 31  ? 15.440  -37.336 7.410   1.00 120.20 ? 31  U   B C5    1 
ATOM   1566 C  C6    . U   B 2 31  ? 15.475  -38.501 8.069   1.00 120.29 ? 31  U   B C6    1 
ATOM   1567 P  P     . C   B 2 32  ? 14.092  -43.612 5.886   1.00 131.86 ? 32  C   B P     1 
ATOM   1568 O  OP1   . C   B 2 32  ? 14.268  -45.066 5.634   1.00 128.74 ? 32  C   B OP1   1 
ATOM   1569 O  OP2   . C   B 2 32  ? 14.881  -42.649 5.075   1.00 130.62 ? 32  C   B OP2   1 
ATOM   1570 O  "O5'" . C   B 2 32  ? 12.554  -43.217 5.724   1.00 137.66 ? 32  C   B "O5'" 1 
ATOM   1571 C  "C5'" . C   B 2 32  ? 11.542  -43.924 6.428   1.00 138.09 ? 32  C   B "C5'" 1 
ATOM   1572 C  "C4'" . C   B 2 32  ? 10.392  -43.033 6.843   1.00 139.60 ? 32  C   B "C4'" 1 
ATOM   1573 O  "O4'" . C   B 2 32  ? 10.885  -41.769 7.366   1.00 134.75 ? 32  C   B "O4'" 1 
ATOM   1574 C  "C3'" . C   B 2 32  ? 9.419   -42.608 5.754   1.00 141.90 ? 32  C   B "C3'" 1 
ATOM   1575 O  "O3'" . C   B 2 32  ? 8.494   -43.615 5.374   1.00 142.39 ? 32  C   B "O3'" 1 
ATOM   1576 C  "C2'" . C   B 2 32  ? 8.761   -41.387 6.376   1.00 135.26 ? 32  C   B "C2'" 1 
ATOM   1577 O  "O2'" . C   B 2 32  ? 7.799   -41.767 7.351   1.00 128.56 ? 32  C   B "O2'" 1 
ATOM   1578 C  "C1'" . C   B 2 32  ? 9.947   -40.743 7.096   1.00 130.54 ? 32  C   B "C1'" 1 
ATOM   1579 N  N1    . C   B 2 32  ? 10.590  -39.690 6.272   1.00 130.41 ? 32  C   B N1    1 
ATOM   1580 C  C2    . C   B 2 32  ? 9.824   -38.591 5.842   1.00 132.24 ? 32  C   B C2    1 
ATOM   1581 O  O2    . C   B 2 32  ? 8.626   -38.534 6.160   1.00 129.72 ? 32  C   B O2    1 
ATOM   1582 N  N3    . C   B 2 32  ? 10.404  -37.630 5.088   1.00 130.97 ? 32  C   B N3    1 
ATOM   1583 C  C4    . C   B 2 32  ? 11.694  -37.722 4.763   1.00 131.24 ? 32  C   B C4    1 
ATOM   1584 N  N4    . C   B 2 32  ? 12.223  -36.745 4.017   1.00 128.56 ? 32  C   B N4    1 
ATOM   1585 C  C5    . C   B 2 32  ? 12.498  -38.822 5.189   1.00 131.34 ? 32  C   B C5    1 
ATOM   1586 C  C6    . C   B 2 32  ? 11.913  -39.772 5.933   1.00 129.01 ? 32  C   B C6    1 
ATOM   1587 P  P     . C   B 2 33  ? 8.062   -43.764 3.830   1.00 143.76 ? 33  C   B P     1 
ATOM   1588 O  OP1   . C   B 2 33  ? 8.226   -45.192 3.459   1.00 145.41 ? 33  C   B OP1   1 
ATOM   1589 O  OP2   . C   B 2 33  ? 8.766   -42.721 3.040   1.00 142.26 ? 33  C   B OP2   1 
ATOM   1590 O  "O5'" . C   B 2 33  ? 6.503   -43.421 3.806   1.00 138.17 ? 33  C   B "O5'" 1 
ATOM   1591 C  "C5'" . C   B 2 33  ? 5.911   -42.594 4.797   1.00 134.97 ? 33  C   B "C5'" 1 
ATOM   1592 C  "C4'" . C   B 2 33  ? 5.161   -41.433 4.189   1.00 134.35 ? 33  C   B "C4'" 1 
ATOM   1593 O  "O4'" . C   B 2 33  ? 5.886   -40.198 4.409   1.00 134.23 ? 33  C   B "O4'" 1 
ATOM   1594 C  "C3'" . C   B 2 33  ? 4.955   -41.471 2.684   1.00 137.32 ? 33  C   B "C3'" 1 
ATOM   1595 O  "O3'" . C   B 2 33  ? 3.892   -42.323 2.296   1.00 136.22 ? 33  C   B "O3'" 1 
ATOM   1596 C  "C2'" . C   B 2 33  ? 4.710   -40.004 2.346   1.00 133.36 ? 33  C   B "C2'" 1 
ATOM   1597 O  "O2'" . C   B 2 33  ? 3.365   -39.645 2.628   1.00 131.23 ? 33  C   B "O2'" 1 
ATOM   1598 C  "C1'" . C   B 2 33  ? 5.621   -39.295 3.355   1.00 132.69 ? 33  C   B "C1'" 1 
ATOM   1599 N  N1    . C   B 2 33  ? 6.900   -38.835 2.760   1.00 135.00 ? 33  C   B N1    1 
ATOM   1600 C  C2    . C   B 2 33  ? 6.901   -37.641 2.026   1.00 136.62 ? 33  C   B C2    1 
ATOM   1601 O  O2    . C   B 2 33  ? 5.833   -37.024 1.896   1.00 139.76 ? 33  C   B O2    1 
ATOM   1602 N  N3    . C   B 2 33  ? 8.053   -37.192 1.474   1.00 132.05 ? 33  C   B N3    1 
ATOM   1603 C  C4    . C   B 2 33  ? 9.182   -37.883 1.638   1.00 132.52 ? 33  C   B C4    1 
ATOM   1604 N  N4    . C   B 2 33  ? 10.300  -37.409 1.083   1.00 124.18 ? 33  C   B N4    1 
ATOM   1605 C  C5    . C   B 2 33  ? 9.214   -39.099 2.383   1.00 135.77 ? 33  C   B C5    1 
ATOM   1606 C  C6    . C   B 2 33  ? 8.065   -39.534 2.923   1.00 133.38 ? 33  C   B C6    1 
ATOM   1607 N  N     . TYR C 1 2   ? 1.957   -29.189 27.868  1.00 98.60  ? 2   TYR C N     1 
ATOM   1608 C  CA    . TYR C 1 2   ? 1.443   -27.967 28.477  1.00 99.96  ? 2   TYR C CA    1 
ATOM   1609 C  C     . TYR C 1 2   ? 0.463   -28.303 29.593  1.00 102.45 ? 2   TYR C C     1 
ATOM   1610 O  O     . TYR C 1 2   ? 0.098   -27.445 30.401  1.00 91.20  ? 2   TYR C O     1 
ATOM   1611 C  CB    . TYR C 1 2   ? 0.755   -27.074 27.442  1.00 103.70 ? 2   TYR C CB    1 
ATOM   1612 C  CG    . TYR C 1 2   ? -0.180  -27.797 26.497  1.00 105.14 ? 2   TYR C CG    1 
ATOM   1613 C  CD1   . TYR C 1 2   ? 0.308   -28.510 25.409  1.00 106.13 ? 2   TYR C CD1   1 
ATOM   1614 C  CD2   . TYR C 1 2   ? -1.557  -27.774 26.703  1.00 105.18 ? 2   TYR C CD2   1 
ATOM   1615 C  CE1   . TYR C 1 2   ? -0.547  -29.167 24.543  1.00 108.16 ? 2   TYR C CE1   1 
ATOM   1616 C  CE2   . TYR C 1 2   ? -2.422  -28.433 25.845  1.00 101.49 ? 2   TYR C CE2   1 
ATOM   1617 C  CZ    . TYR C 1 2   ? -1.912  -29.125 24.765  1.00 101.37 ? 2   TYR C CZ    1 
ATOM   1618 O  OH    . TYR C 1 2   ? -2.771  -29.776 23.907  1.00 90.95  ? 2   TYR C OH    1 
ATOM   1619 N  N     . VAL C 1 3   ? 0.037   -29.565 29.621  1.00 106.94 ? 3   VAL C N     1 
ATOM   1620 C  CA    . VAL C 1 3   ? -0.893  -30.062 30.628  1.00 97.81  ? 3   VAL C CA    1 
ATOM   1621 C  C     . VAL C 1 3   ? -0.259  -29.926 32.006  1.00 99.02  ? 3   VAL C C     1 
ATOM   1622 O  O     . VAL C 1 3   ? 0.697   -30.638 32.338  1.00 99.68  ? 3   VAL C O     1 
ATOM   1623 C  CB    . VAL C 1 3   ? -1.292  -31.517 30.331  1.00 93.35  ? 3   VAL C CB    1 
ATOM   1624 C  CG1   . VAL C 1 3   ? -2.560  -31.884 31.084  1.00 93.94  ? 3   VAL C CG1   1 
ATOM   1625 C  CG2   . VAL C 1 3   ? -1.480  -31.710 28.832  1.00 92.23  ? 3   VAL C CG2   1 
ATOM   1626 N  N     . ARG C 1 4   ? -0.785  -28.999 32.812  1.00 99.89  ? 4   ARG C N     1 
ATOM   1627 C  CA    . ARG C 1 4   ? -0.195  -28.715 34.117  1.00 105.91 ? 4   ARG C CA    1 
ATOM   1628 C  C     . ARG C 1 4   ? -0.352  -29.899 35.065  1.00 107.57 ? 4   ARG C C     1 
ATOM   1629 O  O     . ARG C 1 4   ? 0.635   -30.397 35.621  1.00 112.47 ? 4   ARG C O     1 
ATOM   1630 C  CB    . ARG C 1 4   ? -0.829  -27.455 34.712  1.00 106.67 ? 4   ARG C CB    1 
ATOM   1631 C  CG    . ARG C 1 4   ? -0.258  -26.144 34.175  1.00 101.50 ? 4   ARG C CG    1 
ATOM   1632 C  CD    . ARG C 1 4   ? 0.674   -25.482 35.183  1.00 100.53 ? 4   ARG C CD    1 
ATOM   1633 N  NE    . ARG C 1 4   ? -0.022  -25.094 36.405  1.00 105.40 ? 4   ARG C NE    1 
ATOM   1634 C  CZ    . ARG C 1 4   ? 0.523   -24.392 37.389  1.00 103.23 ? 4   ARG C CZ    1 
ATOM   1635 N  NH1   . ARG C 1 4   ? 1.784   -23.987 37.335  1.00 98.10  ? 4   ARG C NH1   1 
ATOM   1636 N  NH2   . ARG C 1 4   ? -0.214  -24.087 38.455  1.00 93.94  ? 4   ARG C NH2   1 
ATOM   1637 N  N     . PHE C 1 5   ? -1.583  -30.363 35.261  1.00 104.50 ? 5   PHE C N     1 
ATOM   1638 C  CA    . PHE C 1 5   ? -1.864  -31.497 36.128  1.00 108.05 ? 5   PHE C CA    1 
ATOM   1639 C  C     . PHE C 1 5   ? -2.583  -32.581 35.338  1.00 107.85 ? 5   PHE C C     1 
ATOM   1640 O  O     . PHE C 1 5   ? -3.226  -32.317 34.318  1.00 104.12 ? 5   PHE C O     1 
ATOM   1641 C  CB    . PHE C 1 5   ? -2.714  -31.091 37.341  1.00 105.58 ? 5   PHE C CB    1 
ATOM   1642 C  CG    . PHE C 1 5   ? -3.782  -30.080 37.029  1.00 110.57 ? 5   PHE C CG    1 
ATOM   1643 C  CD1   . PHE C 1 5   ? -3.501  -28.722 37.051  1.00 105.74 ? 5   PHE C CD1   1 
ATOM   1644 C  CD2   . PHE C 1 5   ? -5.072  -30.490 36.722  1.00 109.75 ? 5   PHE C CD2   1 
ATOM   1645 C  CE1   . PHE C 1 5   ? -4.481  -27.794 36.764  1.00 98.61  ? 5   PHE C CE1   1 
ATOM   1646 C  CE2   . PHE C 1 5   ? -6.061  -29.567 36.438  1.00 101.48 ? 5   PHE C CE2   1 
ATOM   1647 C  CZ    . PHE C 1 5   ? -5.765  -28.216 36.458  1.00 99.06  ? 5   PHE C CZ    1 
ATOM   1648 N  N     . GLU C 1 6   ? -2.467  -33.814 35.825  1.00 107.52 ? 6   GLU C N     1 
ATOM   1649 C  CA    . GLU C 1 6   ? -3.109  -34.962 35.190  1.00 107.37 ? 6   GLU C CA    1 
ATOM   1650 C  C     . GLU C 1 6   ? -4.467  -35.178 35.848  1.00 109.04 ? 6   GLU C C     1 
ATOM   1651 O  O     . GLU C 1 6   ? -4.567  -35.801 36.907  1.00 108.94 ? 6   GLU C O     1 
ATOM   1652 C  CB    . GLU C 1 6   ? -2.226  -36.201 35.301  1.00 102.45 ? 6   GLU C CB    1 
ATOM   1653 N  N     . VAL C 1 7   ? -5.515  -34.652 35.226  1.00 111.53 ? 7   VAL C N     1 
ATOM   1654 C  CA    . VAL C 1 7   ? -6.880  -34.903 35.706  1.00 109.80 ? 7   VAL C CA    1 
ATOM   1655 C  C     . VAL C 1 7   ? -7.189  -36.389 35.562  1.00 109.68 ? 7   VAL C C     1 
ATOM   1656 O  O     . VAL C 1 7   ? -6.874  -36.985 34.515  1.00 108.80 ? 7   VAL C O     1 
ATOM   1657 C  CB    . VAL C 1 7   ? -7.888  -34.050 34.928  1.00 104.32 ? 7   VAL C CB    1 
ATOM   1658 C  CG1   . VAL C 1 7   ? -9.315  -34.474 35.251  1.00 99.06  ? 7   VAL C CG1   1 
ATOM   1659 C  CG2   . VAL C 1 7   ? -7.695  -32.574 35.246  1.00 98.08  ? 7   VAL C CG2   1 
ATOM   1660 N  N     . PRO C 1 8   ? -7.771  -37.031 36.575  1.00 112.77 ? 8   PRO C N     1 
ATOM   1661 C  CA    . PRO C 1 8   ? -8.085  -38.461 36.461  1.00 109.25 ? 8   PRO C CA    1 
ATOM   1662 C  C     . PRO C 1 8   ? -9.004  -38.737 35.279  1.00 110.11 ? 8   PRO C C     1 
ATOM   1663 O  O     . PRO C 1 8   ? -9.869  -37.927 34.932  1.00 111.27 ? 8   PRO C O     1 
ATOM   1664 C  CB    . PRO C 1 8   ? -8.771  -38.784 37.794  1.00 115.30 ? 8   PRO C CB    1 
ATOM   1665 C  CG    . PRO C 1 8   ? -8.312  -37.714 38.736  1.00 112.64 ? 8   PRO C CG    1 
ATOM   1666 C  CD    . PRO C 1 8   ? -8.063  -36.489 37.913  1.00 107.60 ? 8   PRO C CD    1 
ATOM   1667 N  N     . GLU C 1 9   ? -8.803  -39.906 34.660  1.00 110.28 ? 9   GLU C N     1 
ATOM   1668 C  CA    . GLU C 1 9   ? -9.493  -40.235 33.415  1.00 112.97 ? 9   GLU C CA    1 
ATOM   1669 C  C     . GLU C 1 9   ? -11.006 -40.330 33.582  1.00 111.58 ? 9   GLU C C     1 
ATOM   1670 O  O     . GLU C 1 9   ? -11.729 -40.326 32.581  1.00 110.73 ? 9   GLU C O     1 
ATOM   1671 C  CB    . GLU C 1 9   ? -8.938  -41.545 32.852  1.00 117.77 ? 9   GLU C CB    1 
ATOM   1672 C  CG    . GLU C 1 9   ? -9.294  -41.829 31.396  1.00 118.11 ? 9   GLU C CG    1 
ATOM   1673 C  CD    . GLU C 1 9   ? -9.216  -43.308 31.058  1.00 126.70 ? 9   GLU C CD    1 
ATOM   1674 O  OE1   . GLU C 1 9   ? -8.732  -44.085 31.908  1.00 130.42 ? 9   GLU C OE1   1 
ATOM   1675 O  OE2   . GLU C 1 9   ? -9.627  -43.695 29.942  1.00 128.90 ? 9   GLU C OE2   1 
ATOM   1676 N  N     . ASP C 1 10  ? -11.502 -40.404 34.813  1.00 110.49 ? 10  ASP C N     1 
ATOM   1677 C  CA    . ASP C 1 10  ? -12.937 -40.466 35.048  1.00 110.21 ? 10  ASP C CA    1 
ATOM   1678 C  C     . ASP C 1 10  ? -13.534 -39.129 35.449  1.00 106.91 ? 10  ASP C C     1 
ATOM   1679 O  O     . ASP C 1 10  ? -14.693 -38.859 35.113  1.00 105.65 ? 10  ASP C O     1 
ATOM   1680 C  CB    . ASP C 1 10  ? -13.250 -41.510 36.123  1.00 118.82 ? 10  ASP C CB    1 
ATOM   1681 C  CG    . ASP C 1 10  ? -13.585 -42.856 35.531  1.00 120.10 ? 10  ASP C CG    1 
ATOM   1682 O  OD1   . ASP C 1 10  ? -14.538 -42.918 34.723  1.00 122.24 ? 10  ASP C OD1   1 
ATOM   1683 O  OD2   . ASP C 1 10  ? -12.877 -43.839 35.850  1.00 119.38 ? 10  ASP C OD2   1 
ATOM   1684 N  N     . MET C 1 11  ? -12.777 -38.287 36.156  1.00 104.06 ? 11  MET C N     1 
ATOM   1685 C  CA    . MET C 1 11  ? -13.245 -36.931 36.417  1.00 102.42 ? 11  MET C CA    1 
ATOM   1686 C  C     . MET C 1 11  ? -13.529 -36.190 35.118  1.00 98.96  ? 11  MET C C     1 
ATOM   1687 O  O     . MET C 1 11  ? -14.437 -35.350 35.062  1.00 95.69  ? 11  MET C O     1 
ATOM   1688 C  CB    . MET C 1 11  ? -12.216 -36.175 37.251  1.00 96.17  ? 11  MET C CB    1 
ATOM   1689 C  CG    . MET C 1 11  ? -12.834 -35.348 38.346  1.00 98.25  ? 11  MET C CG    1 
ATOM   1690 S  SD    . MET C 1 11  ? -11.616 -34.329 39.180  1.00 122.30 ? 11  MET C SD    1 
ATOM   1691 C  CE    . MET C 1 11  ? -10.861 -35.547 40.251  1.00 113.62 ? 11  MET C CE    1 
ATOM   1692 N  N     . GLN C 1 12  ? -12.774 -36.505 34.062  1.00 100.36 ? 12  GLN C N     1 
ATOM   1693 C  CA    . GLN C 1 12  ? -13.039 -35.941 32.744  1.00 95.78  ? 12  GLN C CA    1 
ATOM   1694 C  C     . GLN C 1 12  ? -14.410 -36.360 32.222  1.00 95.61  ? 12  GLN C C     1 
ATOM   1695 O  O     . GLN C 1 12  ? -15.128 -35.550 31.624  1.00 93.95  ? 12  GLN C O     1 
ATOM   1696 C  CB    . GLN C 1 12  ? -11.943 -36.372 31.771  1.00 91.65  ? 12  GLN C CB    1 
ATOM   1697 C  CG    . GLN C 1 12  ? -10.540 -36.006 32.209  1.00 88.82  ? 12  GLN C CG    1 
ATOM   1698 C  CD    . GLN C 1 12  ? -9.492  -36.689 31.366  1.00 92.06  ? 12  GLN C CD    1 
ATOM   1699 O  OE1   . GLN C 1 12  ? -9.747  -37.046 30.217  1.00 87.47  ? 12  GLN C OE1   1 
ATOM   1700 N  NE2   . GLN C 1 12  ? -8.298  -36.854 31.919  1.00 100.00 ? 12  GLN C NE2   1 
ATOM   1701 N  N     . ASN C 1 13  ? -14.790 -37.622 32.435  1.00 95.31  ? 13  ASN C N     1 
ATOM   1702 C  CA    . ASN C 1 13  ? -16.113 -38.069 32.011  1.00 91.24  ? 13  ASN C CA    1 
ATOM   1703 C  C     . ASN C 1 13  ? -17.208 -37.414 32.840  1.00 88.22  ? 13  ASN C C     1 
ATOM   1704 O  O     . ASN C 1 13  ? -18.282 -37.097 32.318  1.00 83.80  ? 13  ASN C O     1 
ATOM   1705 C  CB    . ASN C 1 13  ? -16.205 -39.590 32.090  1.00 103.27 ? 13  ASN C CB    1 
ATOM   1706 C  CG    . ASN C 1 13  ? -15.433 -40.276 30.982  1.00 113.58 ? 13  ASN C CG    1 
ATOM   1707 O  OD1   . ASN C 1 13  ? -15.060 -39.649 29.989  1.00 109.58 ? 13  ASN C OD1   1 
ATOM   1708 N  ND2   . ASN C 1 13  ? -15.181 -41.568 31.150  1.00 118.34 ? 13  ASN C ND2   1 
ATOM   1709 N  N     . GLU C 1 14  ? -16.950 -37.190 34.130  1.00 88.55  ? 14  GLU C N     1 
ATOM   1710 C  CA    . GLU C 1 14  ? -17.885 -36.421 34.944  1.00 89.38  ? 14  GLU C CA    1 
ATOM   1711 C  C     . GLU C 1 14  ? -18.093 -35.031 34.359  1.00 94.25  ? 14  GLU C C     1 
ATOM   1712 O  O     . GLU C 1 14  ? -19.233 -34.586 34.168  1.00 92.60  ? 14  GLU C O     1 
ATOM   1713 C  CB    . GLU C 1 14  ? -17.375 -36.327 36.384  1.00 93.19  ? 14  GLU C CB    1 
ATOM   1714 C  CG    . GLU C 1 14  ? -18.011 -35.199 37.198  1.00 92.57  ? 14  GLU C CG    1 
ATOM   1715 C  CD    . GLU C 1 14  ? -18.481 -35.641 38.580  1.00 102.82 ? 14  GLU C CD    1 
ATOM   1716 O  OE1   . GLU C 1 14  ? -17.790 -36.478 39.210  1.00 104.97 ? 14  GLU C OE1   1 
ATOM   1717 O  OE2   . GLU C 1 14  ? -19.546 -35.157 39.033  1.00 97.88  ? 14  GLU C OE2   1 
ATOM   1718 N  N     . ALA C 1 15  ? -16.991 -34.336 34.059  1.00 95.18  ? 15  ALA C N     1 
ATOM   1719 C  CA    . ALA C 1 15  ? -17.078 -32.971 33.550  1.00 81.14  ? 15  ALA C CA    1 
ATOM   1720 C  C     . ALA C 1 15  ? -17.746 -32.926 32.184  1.00 73.49  ? 15  ALA C C     1 
ATOM   1721 O  O     . ALA C 1 15  ? -18.503 -31.995 31.889  1.00 76.13  ? 15  ALA C O     1 
ATOM   1722 C  CB    . ALA C 1 15  ? -15.686 -32.345 33.487  1.00 82.22  ? 15  ALA C CB    1 
ATOM   1723 N  N     . LEU C 1 16  ? -17.490 -33.928 31.342  1.00 72.17  ? 16  LEU C N     1 
ATOM   1724 C  CA    . LEU C 1 16  ? -18.085 -33.953 30.011  1.00 72.32  ? 16  LEU C CA    1 
ATOM   1725 C  C     . LEU C 1 16  ? -19.569 -34.287 30.075  1.00 73.90  ? 16  LEU C C     1 
ATOM   1726 O  O     . LEU C 1 16  ? -20.372 -33.755 29.297  1.00 73.80  ? 16  LEU C O     1 
ATOM   1727 C  CB    . LEU C 1 16  ? -17.338 -34.953 29.141  1.00 69.55  ? 16  LEU C CB    1 
ATOM   1728 C  CG    . LEU C 1 16  ? -16.044 -34.378 28.578  1.00 69.23  ? 16  LEU C CG    1 
ATOM   1729 C  CD1   . LEU C 1 16  ? -15.219 -35.475 27.953  1.00 76.15  ? 16  LEU C CD1   1 
ATOM   1730 C  CD2   . LEU C 1 16  ? -16.361 -33.301 27.554  1.00 80.42  ? 16  LEU C CD2   1 
ATOM   1731 N  N     . SER C 1 17  ? -19.959 -35.153 31.010  1.00 79.67  ? 17  SER C N     1 
ATOM   1732 C  CA    . SER C 1 17  ? -21.377 -35.421 31.199  1.00 85.13  ? 17  SER C CA    1 
ATOM   1733 C  C     . SER C 1 17  ? -22.087 -34.187 31.741  1.00 78.77  ? 17  SER C C     1 
ATOM   1734 O  O     . SER C 1 17  ? -23.206 -33.871 31.324  1.00 80.23  ? 17  SER C O     1 
ATOM   1735 C  CB    . SER C 1 17  ? -21.556 -36.622 32.130  1.00 88.77  ? 17  SER C CB    1 
ATOM   1736 O  OG    . SER C 1 17  ? -22.903 -37.064 32.151  1.00 96.31  ? 17  SER C OG    1 
ATOM   1737 N  N     . LEU C 1 18  ? -21.439 -33.466 32.659  1.00 78.16  ? 18  LEU C N     1 
ATOM   1738 C  CA    . LEU C 1 18  ? -21.986 -32.199 33.133  1.00 76.05  ? 18  LEU C CA    1 
ATOM   1739 C  C     . LEU C 1 18  ? -22.149 -31.207 31.990  1.00 73.34  ? 18  LEU C C     1 
ATOM   1740 O  O     . LEU C 1 18  ? -23.150 -30.484 31.917  1.00 70.76  ? 18  LEU C O     1 
ATOM   1741 C  CB    . LEU C 1 18  ? -21.084 -31.614 34.212  1.00 68.36  ? 18  LEU C CB    1 
ATOM   1742 C  CG    . LEU C 1 18  ? -21.563 -30.244 34.666  1.00 71.79  ? 18  LEU C CG    1 
ATOM   1743 C  CD1   . LEU C 1 18  ? -22.818 -30.394 35.510  1.00 78.10  ? 18  LEU C CD1   1 
ATOM   1744 C  CD2   . LEU C 1 18  ? -20.471 -29.537 35.440  1.00 79.22  ? 18  LEU C CD2   1 
ATOM   1745 N  N     . LEU C 1 19  ? -21.156 -31.146 31.102  1.00 76.08  ? 19  LEU C N     1 
ATOM   1746 C  CA    . LEU C 1 19  ? -21.239 -30.279 29.933  1.00 72.57  ? 19  LEU C CA    1 
ATOM   1747 C  C     . LEU C 1 19  ? -22.434 -30.643 29.056  1.00 74.82  ? 19  LEU C C     1 
ATOM   1748 O  O     . LEU C 1 19  ? -23.117 -29.758 28.528  1.00 75.86  ? 19  LEU C O     1 
ATOM   1749 C  CB    . LEU C 1 19  ? -19.934 -30.372 29.141  1.00 70.31  ? 19  LEU C CB    1 
ATOM   1750 C  CG    . LEU C 1 19  ? -19.677 -29.382 28.010  1.00 67.64  ? 19  LEU C CG    1 
ATOM   1751 C  CD1   . LEU C 1 19  ? -19.950 -27.991 28.511  1.00 68.72  ? 19  LEU C CD1   1 
ATOM   1752 C  CD2   . LEU C 1 19  ? -18.256 -29.504 27.488  1.00 62.57  ? 19  LEU C CD2   1 
ATOM   1753 N  N     . GLU C 1 20  ? -22.695 -31.944 28.877  1.00 78.64  ? 20  GLU C N     1 
ATOM   1754 C  CA    . GLU C 1 20  ? -23.841 -32.334 28.054  1.00 81.04  ? 20  GLU C CA    1 
ATOM   1755 C  C     . GLU C 1 20  ? -25.161 -32.094 28.773  1.00 79.83  ? 20  GLU C C     1 
ATOM   1756 O  O     . GLU C 1 20  ? -26.188 -31.883 28.120  1.00 88.02  ? 20  GLU C O     1 
ATOM   1757 C  CB    . GLU C 1 20  ? -23.742 -33.800 27.624  1.00 82.60  ? 20  GLU C CB    1 
ATOM   1758 C  CG    . GLU C 1 20  ? -22.755 -34.054 26.487  1.00 93.75  ? 20  GLU C CG    1 
ATOM   1759 C  CD    . GLU C 1 20  ? -22.828 -35.471 25.926  1.00 102.86 ? 20  GLU C CD    1 
ATOM   1760 O  OE1   . GLU C 1 20  ? -23.953 -35.989 25.761  1.00 111.55 ? 20  GLU C OE1   1 
ATOM   1761 O  OE2   . GLU C 1 20  ? -21.763 -36.073 25.659  1.00 101.25 ? 20  GLU C OE2   1 
ATOM   1762 N  N     . LYS C 1 21  ? -25.159 -32.124 30.105  1.00 76.37  ? 21  LYS C N     1 
ATOM   1763 C  CA    . LYS C 1 21  ? -26.397 -31.904 30.845  1.00 72.43  ? 21  LYS C CA    1 
ATOM   1764 C  C     . LYS C 1 21  ? -26.771 -30.428 30.881  1.00 71.02  ? 21  LYS C C     1 
ATOM   1765 O  O     . LYS C 1 21  ? -27.934 -30.073 30.652  1.00 70.09  ? 21  LYS C O     1 
ATOM   1766 C  CB    . LYS C 1 21  ? -26.264 -32.472 32.261  1.00 70.80  ? 21  LYS C CB    1 
ATOM   1767 C  CG    . LYS C 1 21  ? -26.184 -33.993 32.277  1.00 74.19  ? 21  LYS C CG    1 
ATOM   1768 C  CD    . LYS C 1 21  ? -26.602 -34.595 33.603  1.00 81.39  ? 21  LYS C CD    1 
ATOM   1769 C  CE    . LYS C 1 21  ? -25.581 -34.329 34.691  1.00 80.54  ? 21  LYS C CE    1 
ATOM   1770 N  NZ    . LYS C 1 21  ? -26.114 -34.694 36.033  1.00 79.58  ? 21  LYS C NZ    1 
ATOM   1771 N  N     . VAL C 1 22  ? -25.792 -29.556 31.137  1.00 77.45  ? 22  VAL C N     1 
ATOM   1772 C  CA    . VAL C 1 22  ? -26.027 -28.116 31.186  1.00 74.05  ? 22  VAL C CA    1 
ATOM   1773 C  C     . VAL C 1 22  ? -26.516 -27.562 29.855  1.00 73.62  ? 22  VAL C C     1 
ATOM   1774 O  O     . VAL C 1 22  ? -27.025 -26.437 29.807  1.00 72.44  ? 22  VAL C O     1 
ATOM   1775 C  CB    . VAL C 1 22  ? -24.728 -27.420 31.655  1.00 68.64  ? 22  VAL C CB    1 
ATOM   1776 C  CG1   . VAL C 1 22  ? -24.849 -25.904 31.641  1.00 71.21  ? 22  VAL C CG1   1 
ATOM   1777 C  CG2   . VAL C 1 22  ? -24.357 -27.884 33.051  1.00 76.73  ? 22  VAL C CG2   1 
ATOM   1778 N  N     . ARG C 1 23  ? -26.431 -28.352 28.780  1.00 79.43  ? 23  ARG C N     1 
ATOM   1779 C  CA    . ARG C 1 23  ? -26.782 -27.875 27.446  1.00 82.91  ? 23  ARG C CA    1 
ATOM   1780 C  C     . ARG C 1 23  ? -28.152 -27.208 27.399  1.00 82.94  ? 23  ARG C C     1 
ATOM   1781 O  O     . ARG C 1 23  ? -28.377 -26.306 26.583  1.00 81.32  ? 23  ARG C O     1 
ATOM   1782 C  CB    . ARG C 1 23  ? -26.744 -29.042 26.459  1.00 85.18  ? 23  ARG C CB    1 
ATOM   1783 C  CG    . ARG C 1 23  ? -25.347 -29.452 26.026  1.00 85.43  ? 23  ARG C CG    1 
ATOM   1784 C  CD    . ARG C 1 23  ? -25.412 -30.555 24.975  1.00 93.90  ? 23  ARG C CD    1 
ATOM   1785 N  NE    . ARG C 1 23  ? -26.532 -30.379 24.055  1.00 100.84 ? 23  ARG C NE    1 
ATOM   1786 C  CZ    . ARG C 1 23  ? -26.576 -29.461 23.096  1.00 101.41 ? 23  ARG C CZ    1 
ATOM   1787 N  NH1   . ARG C 1 23  ? -25.574 -28.618 22.897  1.00 95.31  ? 23  ARG C NH1   1 
ATOM   1788 N  NH2   . ARG C 1 23  ? -27.654 -29.383 22.320  1.00 99.78  ? 23  ARG C NH2   1 
ATOM   1789 N  N     . GLU C 1 24  ? -29.073 -27.617 28.270  1.00 86.57  ? 24  GLU C N     1 
ATOM   1790 C  CA    . GLU C 1 24  ? -30.456 -27.162 28.178  1.00 84.02  ? 24  GLU C CA    1 
ATOM   1791 C  C     . GLU C 1 24  ? -30.725 -25.940 29.054  1.00 81.21  ? 24  GLU C C     1 
ATOM   1792 O  O     . GLU C 1 24  ? -31.091 -24.874 28.546  1.00 82.84  ? 24  GLU C O     1 
ATOM   1793 C  CB    . GLU C 1 24  ? -31.396 -28.311 28.546  1.00 86.98  ? 24  GLU C CB    1 
ATOM   1794 C  CG    . GLU C 1 24  ? -31.031 -29.611 27.853  1.00 104.71 ? 24  GLU C CG    1 
ATOM   1795 C  CD    . GLU C 1 24  ? -32.245 -30.374 27.360  1.00 121.80 ? 24  GLU C CD    1 
ATOM   1796 O  OE1   . GLU C 1 24  ? -33.309 -30.285 28.015  1.00 120.20 ? 24  GLU C OE1   1 
ATOM   1797 O  OE2   . GLU C 1 24  ? -32.134 -31.058 26.318  1.00 125.98 ? 24  GLU C OE2   1 
ATOM   1798 N  N     . SER C 1 25  ? -30.548 -26.080 30.369  1.00 77.89  ? 25  SER C N     1 
ATOM   1799 C  CA    . SER C 1 25  ? -30.893 -25.019 31.309  1.00 74.80  ? 25  SER C CA    1 
ATOM   1800 C  C     . SER C 1 25  ? -29.870 -23.885 31.365  1.00 73.02  ? 25  SER C C     1 
ATOM   1801 O  O     . SER C 1 25  ? -30.144 -22.864 32.003  1.00 67.21  ? 25  SER C O     1 
ATOM   1802 C  CB    . SER C 1 25  ? -31.082 -25.615 32.708  1.00 72.42  ? 25  SER C CB    1 
ATOM   1803 O  OG    . SER C 1 25  ? -30.039 -26.522 33.026  1.00 75.14  ? 25  SER C OG    1 
ATOM   1804 N  N     . GLY C 1 26  ? -28.714 -24.021 30.715  1.00 71.86  ? 26  GLY C N     1 
ATOM   1805 C  CA    . GLY C 1 26  ? -27.674 -23.013 30.828  1.00 65.46  ? 26  GLY C CA    1 
ATOM   1806 C  C     . GLY C 1 26  ? -27.083 -22.544 29.513  1.00 64.73  ? 26  GLY C C     1 
ATOM   1807 O  O     . GLY C 1 26  ? -27.653 -22.785 28.447  1.00 70.39  ? 26  GLY C O     1 
ATOM   1808 N  N     . LYS C 1 27  ? -25.940 -21.863 29.580  1.00 61.41  ? 27  LYS C N     1 
ATOM   1809 C  CA    . LYS C 1 27  ? -25.263 -21.304 28.414  1.00 61.51  ? 27  LYS C CA    1 
ATOM   1810 C  C     . LYS C 1 27  ? -23.823 -21.804 28.363  1.00 64.37  ? 27  LYS C C     1 
ATOM   1811 O  O     . LYS C 1 27  ? -23.089 -21.703 29.354  1.00 66.46  ? 27  LYS C O     1 
ATOM   1812 C  CB    . LYS C 1 27  ? -25.278 -19.769 28.450  1.00 64.57  ? 27  LYS C CB    1 
ATOM   1813 C  CG    . LYS C 1 27  ? -26.001 -19.074 27.304  1.00 69.83  ? 27  LYS C CG    1 
ATOM   1814 C  CD    . LYS C 1 27  ? -25.919 -17.553 27.481  1.00 66.61  ? 27  LYS C CD    1 
ATOM   1815 C  CE    . LYS C 1 27  ? -26.592 -16.793 26.340  1.00 81.87  ? 27  LYS C CE    1 
ATOM   1816 N  NZ    . LYS C 1 27  ? -28.001 -17.237 26.109  1.00 87.68  ? 27  LYS C NZ    1 
ATOM   1817 N  N     . VAL C 1 28  ? -23.415 -22.336 27.210  1.00 60.29  ? 28  VAL C N     1 
ATOM   1818 C  CA    . VAL C 1 28  ? -22.067 -22.870 27.025  1.00 62.97  ? 28  VAL C CA    1 
ATOM   1819 C  C     . VAL C 1 28  ? -21.556 -22.463 25.645  1.00 69.47  ? 28  VAL C C     1 
ATOM   1820 O  O     . VAL C 1 28  ? -22.328 -22.409 24.682  1.00 73.03  ? 28  VAL C O     1 
ATOM   1821 C  CB    . VAL C 1 28  ? -22.032 -24.407 27.187  1.00 60.88  ? 28  VAL C CB    1 
ATOM   1822 C  CG1   . VAL C 1 28  ? -20.640 -24.944 26.897  1.00 64.92  ? 28  VAL C CG1   1 
ATOM   1823 C  CG2   . VAL C 1 28  ? -22.482 -24.824 28.588  1.00 67.32  ? 28  VAL C CG2   1 
ATOM   1824 N  N     . LYS C 1 29  ? -20.251 -22.182 25.548  1.00 67.87  ? 29  LYS C N     1 
ATOM   1825 C  CA    . LYS C 1 29  ? -19.603 -21.819 24.293  1.00 63.44  ? 29  LYS C CA    1 
ATOM   1826 C  C     . LYS C 1 29  ? -18.559 -22.861 23.903  1.00 63.74  ? 29  LYS C C     1 
ATOM   1827 O  O     . LYS C 1 29  ? -17.922 -23.479 24.764  1.00 60.48  ? 29  LYS C O     1 
ATOM   1828 C  CB    . LYS C 1 29  ? -18.931 -20.449 24.392  1.00 58.75  ? 29  LYS C CB    1 
ATOM   1829 C  CG    . LYS C 1 29  ? -19.832 -19.346 24.911  1.00 64.75  ? 29  LYS C CG    1 
ATOM   1830 C  CD    . LYS C 1 29  ? -19.647 -18.062 24.130  1.00 65.11  ? 29  LYS C CD    1 
ATOM   1831 C  CE    . LYS C 1 29  ? -20.688 -17.046 24.538  1.00 69.66  ? 29  LYS C CE    1 
ATOM   1832 N  NZ    . LYS C 1 29  ? -22.065 -17.594 24.364  1.00 74.79  ? 29  LYS C NZ    1 
ATOM   1833 N  N     . LYS C 1 30  ? -18.392 -23.049 22.591  1.00 65.01  ? 30  LYS C N     1 
ATOM   1834 C  CA    . LYS C 1 30  ? -17.394 -23.952 22.033  1.00 65.16  ? 30  LYS C CA    1 
ATOM   1835 C  C     . LYS C 1 30  ? -16.425 -23.178 21.148  1.00 63.91  ? 30  LYS C C     1 
ATOM   1836 O  O     . LYS C 1 30  ? -16.810 -22.226 20.461  1.00 66.16  ? 30  LYS C O     1 
ATOM   1837 C  CB    . LYS C 1 30  ? -18.034 -25.081 21.205  1.00 60.04  ? 30  LYS C CB    1 
ATOM   1838 C  CG    . LYS C 1 30  ? -17.010 -26.082 20.661  1.00 62.59  ? 30  LYS C CG    1 
ATOM   1839 C  CD    . LYS C 1 30  ? -17.588 -27.473 20.428  1.00 72.18  ? 30  LYS C CD    1 
ATOM   1840 C  CE    . LYS C 1 30  ? -18.851 -27.446 19.570  1.00 70.91  ? 30  LYS C CE    1 
ATOM   1841 N  NZ    . LYS C 1 30  ? -18.638 -26.735 18.285  1.00 63.46  ? 30  LYS C NZ    1 
ATOM   1842 N  N     . GLY C 1 31  ? -15.168 -23.603 21.159  1.00 58.41  ? 31  GLY C N     1 
ATOM   1843 C  CA    . GLY C 1 31  ? -14.140 -22.979 20.357  1.00 55.02  ? 31  GLY C CA    1 
ATOM   1844 C  C     . GLY C 1 31  ? -13.269 -22.039 21.174  1.00 60.73  ? 31  GLY C C     1 
ATOM   1845 O  O     . GLY C 1 31  ? -13.630 -21.592 22.266  1.00 62.45  ? 31  GLY C O     1 
ATOM   1846 N  N     . THR C 1 32  ? -12.098 -21.720 20.616  1.00 61.16  ? 32  THR C N     1 
ATOM   1847 C  CA    . THR C 1 32  ? -11.102 -20.953 21.361  1.00 63.79  ? 32  THR C CA    1 
ATOM   1848 C  C     . THR C 1 32  ? -11.445 -19.464 21.427  1.00 66.53  ? 32  THR C C     1 
ATOM   1849 O  O     . THR C 1 32  ? -11.279 -18.838 22.480  1.00 60.19  ? 32  THR C O     1 
ATOM   1850 C  CB    . THR C 1 32  ? -9.720  -21.161 20.742  1.00 59.73  ? 32  THR C CB    1 
ATOM   1851 O  OG1   . THR C 1 32  ? -9.600  -22.519 20.301  1.00 61.75  ? 32  THR C OG1   1 
ATOM   1852 C  CG2   . THR C 1 32  ? -8.631  -20.877 21.765  1.00 60.00  ? 32  THR C CG2   1 
ATOM   1853 N  N     . ASN C 1 33  ? -11.916 -18.879 20.321  1.00 66.38  ? 33  ASN C N     1 
ATOM   1854 C  CA    . ASN C 1 33  ? -12.263 -17.458 20.316  1.00 63.61  ? 33  ASN C CA    1 
ATOM   1855 C  C     . ASN C 1 33  ? -13.313 -17.139 21.364  1.00 67.18  ? 33  ASN C C     1 
ATOM   1856 O  O     . ASN C 1 33  ? -13.116 -16.261 22.215  1.00 69.02  ? 33  ASN C O     1 
ATOM   1857 C  CB    . ASN C 1 33  ? -12.776 -17.031 18.942  1.00 65.68  ? 33  ASN C CB    1 
ATOM   1858 C  CG    . ASN C 1 33  ? -11.706 -17.036 17.896  1.00 66.99  ? 33  ASN C CG    1 
ATOM   1859 O  OD1   . ASN C 1 33  ? -10.541 -17.303 18.186  1.00 75.35  ? 33  ASN C OD1   1 
ATOM   1860 N  ND2   . ASN C 1 33  ? -12.089 -16.720 16.663  1.00 60.22  ? 33  ASN C ND2   1 
ATOM   1861 N  N     . SER C 1 34  ? -14.456 -17.820 21.290  1.00 65.19  ? 34  SER C N     1 
ATOM   1862 C  CA    . SER C 1 34  ? -15.537 -17.538 22.224  1.00 64.36  ? 34  SER C CA    1 
ATOM   1863 C  C     . SER C 1 34  ? -15.135 -17.867 23.659  1.00 65.65  ? 34  SER C C     1 
ATOM   1864 O  O     . SER C 1 34  ? -15.523 -17.152 24.587  1.00 61.83  ? 34  SER C O     1 
ATOM   1865 C  CB    . SER C 1 34  ? -16.794 -18.297 21.801  1.00 63.33  ? 34  SER C CB    1 
ATOM   1866 O  OG    . SER C 1 34  ? -16.486 -19.636 21.466  1.00 70.09  ? 34  SER C OG    1 
ATOM   1867 N  N     . THR C 1 35  ? -14.328 -18.917 23.862  1.00 63.45  ? 35  THR C N     1 
ATOM   1868 C  CA    . THR C 1 35  ? -13.898 -19.271 25.215  1.00 58.85  ? 35  THR C CA    1 
ATOM   1869 C  C     . THR C 1 35  ? -13.010 -18.191 25.810  1.00 65.18  ? 35  THR C C     1 
ATOM   1870 O  O     . THR C 1 35  ? -13.196 -17.773 26.963  1.00 65.99  ? 35  THR C O     1 
ATOM   1871 C  CB    . THR C 1 35  ? -13.152 -20.603 25.220  1.00 57.33  ? 35  THR C CB    1 
ATOM   1872 O  OG1   . THR C 1 35  ? -13.983 -21.624 24.657  1.00 62.76  ? 35  THR C OG1   1 
ATOM   1873 C  CG2   . THR C 1 35  ? -12.783 -20.981 26.644  1.00 53.72  ? 35  THR C CG2   1 
ATOM   1874 N  N     . THR C 1 36  ? -12.021 -17.739 25.038  1.00 67.49  ? 36  THR C N     1 
ATOM   1875 C  CA    . THR C 1 36  ? -11.134 -16.685 25.511  1.00 61.79  ? 36  THR C CA    1 
ATOM   1876 C  C     . THR C 1 36  ? -11.912 -15.404 25.762  1.00 60.38  ? 36  THR C C     1 
ATOM   1877 O  O     . THR C 1 36  ? -11.690 -14.722 26.769  1.00 60.88  ? 36  THR C O     1 
ATOM   1878 C  CB    . THR C 1 36  ? -10.015 -16.451 24.499  1.00 56.90  ? 36  THR C CB    1 
ATOM   1879 O  OG1   . THR C 1 36  ? -9.583  -17.710 23.976  1.00 64.79  ? 36  THR C OG1   1 
ATOM   1880 C  CG2   . THR C 1 36  ? -8.836  -15.778 25.157  1.00 59.60  ? 36  THR C CG2   1 
ATOM   1881 N  N     . LEU C 1 37  ? -12.849 -15.074 24.870  1.00 61.02  ? 37  LEU C N     1 
ATOM   1882 C  CA    . LEU C 1 37  ? -13.646 -13.869 25.063  1.00 64.40  ? 37  LEU C CA    1 
ATOM   1883 C  C     . LEU C 1 37  ? -14.510 -13.973 26.311  1.00 65.54  ? 37  LEU C C     1 
ATOM   1884 O  O     . LEU C 1 37  ? -14.716 -12.978 27.012  1.00 66.54  ? 37  LEU C O     1 
ATOM   1885 C  CB    . LEU C 1 37  ? -14.509 -13.607 23.831  1.00 65.67  ? 37  LEU C CB    1 
ATOM   1886 C  CG    . LEU C 1 37  ? -14.159 -12.323 23.088  1.00 67.38  ? 37  LEU C CG    1 
ATOM   1887 C  CD1   . LEU C 1 37  ? -15.267 -11.968 22.114  1.00 80.35  ? 37  LEU C CD1   1 
ATOM   1888 C  CD2   . LEU C 1 37  ? -13.922 -11.189 24.077  1.00 71.56  ? 37  LEU C CD2   1 
ATOM   1889 N  N     . ALA C 1 38  ? -15.014 -15.171 26.613  1.00 64.11  ? 38  ALA C N     1 
ATOM   1890 C  CA    . ALA C 1 38  ? -15.838 -15.350 27.800  1.00 58.66  ? 38  ALA C CA    1 
ATOM   1891 C  C     . ALA C 1 38  ? -15.010 -15.202 29.068  1.00 61.61  ? 38  ALA C C     1 
ATOM   1892 O  O     . ALA C 1 38  ? -15.420 -14.509 30.006  1.00 68.54  ? 38  ALA C O     1 
ATOM   1893 C  CB    . ALA C 1 38  ? -16.527 -16.711 27.758  1.00 62.47  ? 38  ALA C CB    1 
ATOM   1894 N  N     . VAL C 1 39  ? -13.841 -15.845 29.119  1.00 60.38  ? 39  VAL C N     1 
ATOM   1895 C  CA    . VAL C 1 39  ? -12.987 -15.684 30.295  1.00 65.57  ? 39  VAL C CA    1 
ATOM   1896 C  C     . VAL C 1 39  ? -12.592 -14.225 30.471  1.00 69.38  ? 39  VAL C C     1 
ATOM   1897 O  O     . VAL C 1 39  ? -12.617 -13.691 31.587  1.00 73.40  ? 39  VAL C O     1 
ATOM   1898 C  CB    . VAL C 1 39  ? -11.742 -16.584 30.213  1.00 60.37  ? 39  VAL C CB    1 
ATOM   1899 C  CG1   . VAL C 1 39  ? -11.021 -16.575 31.552  1.00 66.05  ? 39  VAL C CG1   1 
ATOM   1900 C  CG2   . VAL C 1 39  ? -12.122 -17.996 29.846  1.00 62.02  ? 39  VAL C CG2   1 
ATOM   1901 N  N     . SER C 1 40  ? -12.204 -13.563 29.377  1.00 67.77  ? 40  SER C N     1 
ATOM   1902 C  CA    . SER C 1 40  ? -11.789 -12.168 29.463  1.00 63.18  ? 40  SER C CA    1 
ATOM   1903 C  C     . SER C 1 40  ? -12.919 -11.298 29.983  1.00 64.51  ? 40  SER C C     1 
ATOM   1904 O  O     . SER C 1 40  ? -12.698 -10.404 30.807  1.00 72.81  ? 40  SER C O     1 
ATOM   1905 C  CB    . SER C 1 40  ? -11.327 -11.665 28.096  1.00 65.60  ? 40  SER C CB    1 
ATOM   1906 O  OG    . SER C 1 40  ? -10.481 -12.612 27.466  1.00 68.27  ? 40  SER C OG    1 
ATOM   1907 N  N     . ARG C 1 41  ? -14.143 -11.563 29.534  1.00 62.24  ? 41  ARG C N     1 
ATOM   1908 C  CA    . ARG C 1 41  ? -15.287 -10.744 29.901  1.00 62.73  ? 41  ARG C CA    1 
ATOM   1909 C  C     . ARG C 1 41  ? -15.879 -11.121 31.243  1.00 68.44  ? 41  ARG C C     1 
ATOM   1910 O  O     . ARG C 1 41  ? -16.990 -10.680 31.553  1.00 71.11  ? 41  ARG C O     1 
ATOM   1911 C  CB    . ARG C 1 41  ? -16.353 -10.817 28.809  1.00 57.17  ? 41  ARG C CB    1 
ATOM   1912 C  CG    . ARG C 1 41  ? -15.877 -10.222 27.502  1.00 62.76  ? 41  ARG C CG    1 
ATOM   1913 C  CD    . ARG C 1 41  ? -16.787 -10.605 26.360  1.00 67.83  ? 41  ARG C CD    1 
ATOM   1914 N  NE    . ARG C 1 41  ? -16.631 -9.720  25.213  1.00 81.34  ? 41  ARG C NE    1 
ATOM   1915 C  CZ    . ARG C 1 41  ? -17.246 -9.893  24.051  1.00 89.28  ? 41  ARG C CZ    1 
ATOM   1916 N  NH1   . ARG C 1 41  ? -18.084 -10.898 23.857  1.00 93.04  ? 41  ARG C NH1   1 
ATOM   1917 N  NH2   . ARG C 1 41  ? -17.011 -9.039  23.058  1.00 92.97  ? 41  ARG C NH2   1 
ATOM   1918 N  N     . GLY C 1 42  ? -15.167 -11.901 32.051  1.00 69.57  ? 42  GLY C N     1 
ATOM   1919 C  CA    . GLY C 1 42  ? -15.620 -12.202 33.395  1.00 66.70  ? 42  GLY C CA    1 
ATOM   1920 C  C     . GLY C 1 42  ? -16.964 -12.886 33.405  1.00 60.54  ? 42  GLY C C     1 
ATOM   1921 O  O     . GLY C 1 42  ? -17.894 -12.493 34.131  1.00 71.41  ? 42  GLY C O     1 
ATOM   1922 N  N     . LEU C 1 43  ? -17.055 -13.929 32.577  1.00 63.12  ? 43  LEU C N     1 
ATOM   1923 C  CA    . LEU C 1 43  ? -18.288 -14.701 32.468  1.00 69.44  ? 43  LEU C CA    1 
ATOM   1924 C  C     . LEU C 1 43  ? -18.079 -16.213 32.555  1.00 65.35  ? 43  LEU C C     1 
ATOM   1925 O  O     . LEU C 1 43  ? -18.992 -16.932 32.986  1.00 65.33  ? 43  LEU C O     1 
ATOM   1926 C  CB    . LEU C 1 43  ? -19.022 -14.377 31.179  1.00 62.35  ? 43  LEU C CB    1 
ATOM   1927 C  CG    . LEU C 1 43  ? -19.374 -12.904 30.913  1.00 57.98  ? 43  LEU C CG    1 
ATOM   1928 C  CD1   . LEU C 1 43  ? -19.573 -12.717 29.408  1.00 61.62  ? 43  LEU C CD1   1 
ATOM   1929 C  CD2   . LEU C 1 43  ? -20.624 -12.519 31.673  1.00 63.02  ? 43  LEU C CD2   1 
ATOM   1930 N  N     . ALA C 1 44  ? -16.919 -16.742 32.163  1.00 58.57  ? 44  ALA C N     1 
ATOM   1931 C  CA    . ALA C 1 44  ? -16.740 -18.188 32.142  1.00 59.94  ? 44  ALA C CA    1 
ATOM   1932 C  C     . ALA C 1 44  ? -16.810 -18.767 33.546  1.00 63.74  ? 44  ALA C C     1 
ATOM   1933 O  O     . ALA C 1 44  ? -16.184 -18.256 34.480  1.00 64.65  ? 44  ALA C O     1 
ATOM   1934 C  CB    . ALA C 1 44  ? -15.408 -18.541 31.504  1.00 60.00  ? 44  ALA C CB    1 
ATOM   1935 N  N     . LYS C 1 45  ? -17.574 -19.843 33.693  1.00 67.80  ? 45  LYS C N     1 
ATOM   1936 C  CA    . LYS C 1 45  ? -17.672 -20.539 34.967  1.00 61.80  ? 45  LYS C CA    1 
ATOM   1937 C  C     . LYS C 1 45  ? -16.868 -21.825 35.011  1.00 57.74  ? 45  LYS C C     1 
ATOM   1938 O  O     . LYS C 1 45  ? -16.413 -22.210 36.090  1.00 65.00  ? 45  LYS C O     1 
ATOM   1939 C  CB    . LYS C 1 45  ? -19.134 -20.858 35.308  1.00 61.90  ? 45  LYS C CB    1 
ATOM   1940 C  CG    . LYS C 1 45  ? -20.060 -19.684 35.022  1.00 60.51  ? 45  LYS C CG    1 
ATOM   1941 C  CD    . LYS C 1 45  ? -21.209 -19.599 36.009  1.00 63.23  ? 45  LYS C CD    1 
ATOM   1942 C  CE    . LYS C 1 45  ? -20.765 -18.919 37.293  1.00 79.85  ? 45  LYS C CE    1 
ATOM   1943 N  NZ    . LYS C 1 45  ? -20.324 -17.504 37.046  1.00 82.41  ? 45  LYS C NZ    1 
ATOM   1944 N  N     . LEU C 1 46  ? -16.665 -22.503 33.879  1.00 54.97  ? 46  LEU C N     1 
ATOM   1945 C  CA    . LEU C 1 46  ? -15.787 -23.681 33.881  1.00 59.24  ? 46  LEU C CA    1 
ATOM   1946 C  C     . LEU C 1 46  ? -15.296 -23.921 32.461  1.00 57.82  ? 46  LEU C C     1 
ATOM   1947 O  O     . LEU C 1 46  ? -16.096 -24.249 31.586  1.00 60.83  ? 46  LEU C O     1 
ATOM   1948 C  CB    . LEU C 1 46  ? -16.517 -24.910 34.422  1.00 63.22  ? 46  LEU C CB    1 
ATOM   1949 C  CG    . LEU C 1 46  ? -15.819 -26.275 34.367  1.00 59.97  ? 46  LEU C CG    1 
ATOM   1950 C  CD1   . LEU C 1 46  ? -14.405 -26.207 34.921  1.00 58.97  ? 46  LEU C CD1   1 
ATOM   1951 C  CD2   . LEU C 1 46  ? -16.657 -27.304 35.104  1.00 61.78  ? 46  LEU C CD2   1 
ATOM   1952 N  N     . VAL C 1 47  ? -13.998 -23.773 32.230  1.00 52.86  ? 47  VAL C N     1 
ATOM   1953 C  CA    . VAL C 1 47  ? -13.455 -23.951 30.889  1.00 57.03  ? 47  VAL C CA    1 
ATOM   1954 C  C     . VAL C 1 47  ? -12.854 -25.343 30.753  1.00 58.92  ? 47  VAL C C     1 
ATOM   1955 O  O     . VAL C 1 47  ? -12.380 -25.950 31.721  1.00 63.44  ? 47  VAL C O     1 
ATOM   1956 C  CB    . VAL C 1 47  ? -12.422 -22.862 30.537  1.00 54.65  ? 47  VAL C CB    1 
ATOM   1957 C  CG1   . VAL C 1 47  ? -13.016 -21.489 30.754  1.00 56.18  ? 47  VAL C CG1   1 
ATOM   1958 C  CG2   . VAL C 1 47  ? -11.189 -23.033 31.367  1.00 64.24  ? 47  VAL C CG2   1 
ATOM   1959 N  N     . TYR C 1 48  ? -12.884 -25.851 29.525  1.00 52.00  ? 48  TYR C N     1 
ATOM   1960 C  CA    . TYR C 1 48  ? -12.410 -27.183 29.185  1.00 54.64  ? 48  TYR C CA    1 
ATOM   1961 C  C     . TYR C 1 48  ? -11.345 -27.051 28.106  1.00 57.65  ? 48  TYR C C     1 
ATOM   1962 O  O     . TYR C 1 48  ? -11.572 -26.376 27.095  1.00 61.55  ? 48  TYR C O     1 
ATOM   1963 C  CB    . TYR C 1 48  ? -13.551 -28.062 28.664  1.00 60.83  ? 48  TYR C CB    1 
ATOM   1964 C  CG    . TYR C 1 48  ? -14.670 -28.369 29.636  1.00 56.84  ? 48  TYR C CG    1 
ATOM   1965 C  CD1   . TYR C 1 48  ? -15.547 -27.375 30.061  1.00 52.56  ? 48  TYR C CD1   1 
ATOM   1966 C  CD2   . TYR C 1 48  ? -14.886 -29.668 30.079  1.00 57.95  ? 48  TYR C CD2   1 
ATOM   1967 C  CE1   . TYR C 1 48  ? -16.581 -27.659 30.934  1.00 56.26  ? 48  TYR C CE1   1 
ATOM   1968 C  CE2   . TYR C 1 48  ? -15.915 -29.964 30.947  1.00 63.02  ? 48  TYR C CE2   1 
ATOM   1969 C  CZ    . TYR C 1 48  ? -16.762 -28.959 31.373  1.00 64.55  ? 48  TYR C CZ    1 
ATOM   1970 O  OH    . TYR C 1 48  ? -17.787 -29.269 32.240  1.00 61.79  ? 48  TYR C OH    1 
ATOM   1971 N  N     . ILE C 1 49  ? -10.202 -27.701 28.311  1.00 58.72  ? 49  ILE C N     1 
ATOM   1972 C  CA    . ILE C 1 49  ? -9.078  -27.644 27.384  1.00 58.10  ? 49  ILE C CA    1 
ATOM   1973 C  C     . ILE C 1 49  ? -8.801  -29.049 26.876  1.00 60.02  ? 49  ILE C C     1 
ATOM   1974 O  O     . ILE C 1 49  ? -8.814  -30.012 27.650  1.00 66.47  ? 49  ILE C O     1 
ATOM   1975 C  CB    . ILE C 1 49  ? -7.818  -27.046 28.045  1.00 61.14  ? 49  ILE C CB    1 
ATOM   1976 C  CG1   . ILE C 1 49  ? -8.192  -25.846 28.917  1.00 61.77  ? 49  ILE C CG1   1 
ATOM   1977 C  CG2   . ILE C 1 49  ? -6.803  -26.648 26.994  1.00 62.56  ? 49  ILE C CG2   1 
ATOM   1978 C  CD1   . ILE C 1 49  ? -7.022  -25.129 29.531  1.00 61.32  ? 49  ILE C CD1   1 
ATOM   1979 N  N     . ALA C 1 50  ? -8.550  -29.168 25.581  1.00 58.58  ? 50  ALA C N     1 
ATOM   1980 C  CA    . ALA C 1 50  ? -8.246  -30.466 25.005  1.00 65.61  ? 50  ALA C CA    1 
ATOM   1981 C  C     . ALA C 1 50  ? -6.751  -30.747 25.101  1.00 71.66  ? 50  ALA C C     1 
ATOM   1982 O  O     . ALA C 1 50  ? -5.933  -29.843 25.293  1.00 74.71  ? 50  ALA C O     1 
ATOM   1983 C  CB    . ALA C 1 50  ? -8.712  -30.537 23.551  1.00 67.01  ? 50  ALA C CB    1 
ATOM   1984 N  N     . GLU C 1 51  ? -6.404  -32.027 24.977  1.00 70.53  ? 51  GLU C N     1 
ATOM   1985 C  CA    . GLU C 1 51  ? -5.024  -32.479 25.073  1.00 73.67  ? 51  GLU C CA    1 
ATOM   1986 C  C     . GLU C 1 51  ? -4.418  -32.856 23.726  1.00 75.89  ? 51  GLU C C     1 
ATOM   1987 O  O     . GLU C 1 51  ? -3.217  -33.138 23.662  1.00 86.14  ? 51  GLU C O     1 
ATOM   1988 C  CB    . GLU C 1 51  ? -4.921  -33.668 26.043  1.00 78.55  ? 51  GLU C CB    1 
ATOM   1989 C  CG    . GLU C 1 51  ? -5.187  -33.325 27.512  1.00 77.12  ? 51  GLU C CG    1 
ATOM   1990 C  CD    . GLU C 1 51  ? -4.982  -34.513 28.452  1.00 85.16  ? 51  GLU C CD    1 
ATOM   1991 O  OE1   . GLU C 1 51  ? -4.993  -35.670 27.976  1.00 84.32  ? 51  GLU C OE1   1 
ATOM   1992 O  OE2   . GLU C 1 51  ? -4.802  -34.288 29.670  1.00 85.87  ? 51  GLU C OE2   1 
ATOM   1993 N  N     . ASP C 1 52  ? -5.201  -32.854 22.648  1.00 70.51  ? 52  ASP C N     1 
ATOM   1994 C  CA    . ASP C 1 52  ? -4.699  -33.215 21.328  1.00 69.13  ? 52  ASP C CA    1 
ATOM   1995 C  C     . ASP C 1 52  ? -4.576  -32.009 20.409  1.00 72.78  ? 52  ASP C C     1 
ATOM   1996 O  O     . ASP C 1 52  ? -4.507  -32.169 19.186  1.00 74.06  ? 52  ASP C O     1 
ATOM   1997 C  CB    . ASP C 1 52  ? -5.595  -34.273 20.689  1.00 69.28  ? 52  ASP C CB    1 
ATOM   1998 C  CG    . ASP C 1 52  ? -7.064  -33.943 20.822  1.00 75.45  ? 52  ASP C CG    1 
ATOM   1999 O  OD1   . ASP C 1 52  ? -7.397  -33.036 21.614  1.00 79.91  ? 52  ASP C OD1   1 
ATOM   2000 O  OD2   . ASP C 1 52  ? -7.888  -34.595 20.145  1.00 73.53  ? 52  ASP C OD2   1 
ATOM   2001 N  N     . VAL C 1 53  ? -4.541  -30.805 20.974  1.00 74.03  ? 53  VAL C N     1 
ATOM   2002 C  CA    . VAL C 1 53  ? -4.464  -29.601 20.159  1.00 76.88  ? 53  VAL C CA    1 
ATOM   2003 C  C     . VAL C 1 53  ? -3.071  -29.512 19.546  1.00 80.86  ? 53  VAL C C     1 
ATOM   2004 O  O     . VAL C 1 53  ? -2.062  -29.437 20.259  1.00 81.93  ? 53  VAL C O     1 
ATOM   2005 C  CB    . VAL C 1 53  ? -4.798  -28.356 20.989  1.00 76.73  ? 53  VAL C CB    1 
ATOM   2006 C  CG1   . VAL C 1 53  ? -4.909  -27.130 20.090  1.00 73.95  ? 53  VAL C CG1   1 
ATOM   2007 C  CG2   . VAL C 1 53  ? -6.078  -28.577 21.776  1.00 69.10  ? 53  VAL C CG2   1 
ATOM   2008 N  N     . ASP C 1 54  ? -3.012  -29.538 18.216  1.00 77.58  ? 54  ASP C N     1 
ATOM   2009 C  CA    . ASP C 1 54  ? -1.764  -29.408 17.473  1.00 74.14  ? 54  ASP C CA    1 
ATOM   2010 C  C     . ASP C 1 54  ? -1.973  -28.345 16.404  1.00 77.19  ? 54  ASP C C     1 
ATOM   2011 O  O     . ASP C 1 54  ? -2.831  -28.526 15.515  1.00 75.79  ? 54  ASP C O     1 
ATOM   2012 C  CB    . ASP C 1 54  ? -1.350  -30.747 16.855  1.00 74.23  ? 54  ASP C CB    1 
ATOM   2013 C  CG    . ASP C 1 54  ? 0.153   -30.895 16.742  1.00 87.27  ? 54  ASP C CG    1 
ATOM   2014 O  OD1   . ASP C 1 54  ? 0.866   -30.358 17.618  1.00 88.89  ? 54  ASP C OD1   1 
ATOM   2015 O  OD2   . ASP C 1 54  ? 0.618   -31.564 15.791  1.00 84.92  ? 54  ASP C OD2   1 
ATOM   2016 N  N     . PRO C 1 55  ? -1.236  -27.224 16.435  1.00 80.61  ? 55  PRO C N     1 
ATOM   2017 C  CA    . PRO C 1 55  ? -0.175  -26.835 17.381  1.00 79.89  ? 55  PRO C CA    1 
ATOM   2018 C  C     . PRO C 1 55  ? -0.699  -26.497 18.771  1.00 80.59  ? 55  PRO C C     1 
ATOM   2019 O  O     . PRO C 1 55  ? -1.843  -26.081 18.930  1.00 81.68  ? 55  PRO C O     1 
ATOM   2020 C  CB    . PRO C 1 55  ? 0.441   -25.597 16.714  1.00 77.49  ? 55  PRO C CB    1 
ATOM   2021 C  CG    . PRO C 1 55  ? -0.688  -25.004 15.937  1.00 75.29  ? 55  PRO C CG    1 
ATOM   2022 C  CD    . PRO C 1 55  ? -1.451  -26.187 15.411  1.00 79.36  ? 55  PRO C CD    1 
ATOM   2023 N  N     . PRO C 1 56  ? 0.136   -26.648 19.803  1.00 80.74  ? 56  PRO C N     1 
ATOM   2024 C  CA    . PRO C 1 56  ? -0.334  -26.419 21.174  1.00 79.57  ? 56  PRO C CA    1 
ATOM   2025 C  C     . PRO C 1 56  ? -0.431  -24.954 21.562  1.00 75.27  ? 56  PRO C C     1 
ATOM   2026 O  O     . PRO C 1 56  ? -0.952  -24.651 22.643  1.00 76.99  ? 56  PRO C O     1 
ATOM   2027 C  CB    . PRO C 1 56  ? 0.720   -27.145 22.030  1.00 82.10  ? 56  PRO C CB    1 
ATOM   2028 C  CG    . PRO C 1 56  ? 1.748   -27.709 21.060  1.00 80.68  ? 56  PRO C CG    1 
ATOM   2029 C  CD    . PRO C 1 56  ? 1.566   -26.986 19.771  1.00 81.85  ? 56  PRO C CD    1 
ATOM   2030 N  N     . GLU C 1 57  ? 0.051   -24.035 20.729  1.00 76.61  ? 57  GLU C N     1 
ATOM   2031 C  CA    . GLU C 1 57  ? -0.035  -22.626 21.082  1.00 77.74  ? 57  GLU C CA    1 
ATOM   2032 C  C     . GLU C 1 57  ? -1.454  -22.090 20.973  1.00 75.53  ? 57  GLU C C     1 
ATOM   2033 O  O     . GLU C 1 57  ? -1.717  -20.973 21.433  1.00 77.51  ? 57  GLU C O     1 
ATOM   2034 C  CB    . GLU C 1 57  ? 0.903   -21.799 20.198  1.00 83.45  ? 57  GLU C CB    1 
ATOM   2035 C  CG    . GLU C 1 57  ? 2.242   -22.476 19.888  1.00 88.68  ? 57  GLU C CG    1 
ATOM   2036 C  CD    . GLU C 1 57  ? 3.116   -22.691 21.121  1.00 95.78  ? 57  GLU C CD    1 
ATOM   2037 O  OE1   . GLU C 1 57  ? 2.893   -22.017 22.159  1.00 90.91  ? 57  GLU C OE1   1 
ATOM   2038 O  OE2   . GLU C 1 57  ? 4.034   -23.543 21.039  1.00 88.03  ? 57  GLU C OE2   1 
ATOM   2039 N  N     . ILE C 1 58  ? -2.365  -22.852 20.368  1.00 72.20  ? 58  ILE C N     1 
ATOM   2040 C  CA    . ILE C 1 58  ? -3.744  -22.401 20.233  1.00 71.14  ? 58  ILE C CA    1 
ATOM   2041 C  C     . ILE C 1 58  ? -4.403  -22.272 21.598  1.00 74.33  ? 58  ILE C C     1 
ATOM   2042 O  O     . ILE C 1 58  ? -5.184  -21.344 21.843  1.00 72.92  ? 58  ILE C O     1 
ATOM   2043 C  CB    . ILE C 1 58  ? -4.517  -23.357 19.308  1.00 66.14  ? 58  ILE C CB    1 
ATOM   2044 C  CG1   . ILE C 1 58  ? -3.840  -23.405 17.940  1.00 65.75  ? 58  ILE C CG1   1 
ATOM   2045 C  CG2   . ILE C 1 58  ? -5.980  -22.936 19.180  1.00 61.45  ? 58  ILE C CG2   1 
ATOM   2046 C  CD1   . ILE C 1 58  ? -4.198  -24.595 17.130  1.00 69.58  ? 58  ILE C CD1   1 
ATOM   2047 N  N     . VAL C 1 59  ? -4.095  -23.188 22.513  1.00 72.48  ? 59  VAL C N     1 
ATOM   2048 C  CA    . VAL C 1 59  ? -4.698  -23.182 23.835  1.00 68.11  ? 59  VAL C CA    1 
ATOM   2049 C  C     . VAL C 1 59  ? -3.675  -22.904 24.930  1.00 72.07  ? 59  VAL C C     1 
ATOM   2050 O  O     . VAL C 1 59  ? -4.032  -22.852 26.105  1.00 74.04  ? 59  VAL C O     1 
ATOM   2051 C  CB    . VAL C 1 59  ? -5.447  -24.502 24.096  1.00 64.05  ? 59  VAL C CB    1 
ATOM   2052 C  CG1   . VAL C 1 59  ? -6.786  -24.473 23.395  1.00 62.04  ? 59  VAL C CG1   1 
ATOM   2053 C  CG2   . VAL C 1 59  ? -4.618  -25.675 23.608  1.00 64.93  ? 59  VAL C CG2   1 
ATOM   2054 N  N     . ALA C 1 60  ? -2.407  -22.694 24.562  1.00 72.88  ? 60  ALA C N     1 
ATOM   2055 C  CA    . ALA C 1 60  ? -1.316  -22.486 25.510  1.00 73.04  ? 60  ALA C CA    1 
ATOM   2056 C  C     . ALA C 1 60  ? -1.523  -21.286 26.425  1.00 66.12  ? 60  ALA C C     1 
ATOM   2057 O  O     . ALA C 1 60  ? -0.870  -21.207 27.471  1.00 68.17  ? 60  ALA C O     1 
ATOM   2058 C  CB    . ALA C 1 60  ? -0.001  -22.323 24.746  1.00 77.01  ? 60  ALA C CB    1 
ATOM   2059 N  N     . HIS C 1 61  ? -2.408  -20.365 26.067  1.00 66.47  ? 61  HIS C N     1 
ATOM   2060 C  CA    . HIS C 1 61  ? -2.642  -19.154 26.837  1.00 68.37  ? 61  HIS C CA    1 
ATOM   2061 C  C     . HIS C 1 61  ? -3.776  -19.290 27.841  1.00 68.25  ? 61  HIS C C     1 
ATOM   2062 O  O     . HIS C 1 61  ? -3.908  -18.433 28.723  1.00 68.29  ? 61  HIS C O     1 
ATOM   2063 C  CB    . HIS C 1 61  ? -2.973  -18.006 25.890  1.00 69.58  ? 61  HIS C CB    1 
ATOM   2064 C  CG    . HIS C 1 61  ? -4.242  -18.222 25.130  1.00 64.87  ? 61  HIS C CG    1 
ATOM   2065 N  ND1   . HIS C 1 61  ? -4.271  -18.839 23.898  1.00 67.76  ? 61  HIS C ND1   1 
ATOM   2066 C  CD2   . HIS C 1 61  ? -5.529  -17.944 25.444  1.00 61.83  ? 61  HIS C CD2   1 
ATOM   2067 C  CE1   . HIS C 1 61  ? -5.520  -18.906 23.474  1.00 66.05  ? 61  HIS C CE1   1 
ATOM   2068 N  NE2   . HIS C 1 61  ? -6.303  -18.371 24.393  1.00 61.97  ? 61  HIS C NE2   1 
ATOM   2069 N  N     . LEU C 1 62  ? -4.595  -20.339 27.727  1.00 67.99  ? 62  LEU C N     1 
ATOM   2070 C  CA    . LEU C 1 62  ? -5.833  -20.395 28.504  1.00 67.33  ? 62  LEU C CA    1 
ATOM   2071 C  C     . LEU C 1 62  ? -5.588  -20.557 29.999  1.00 66.71  ? 62  LEU C C     1 
ATOM   2072 O  O     . LEU C 1 62  ? -6.176  -19.788 30.779  1.00 67.58  ? 62  LEU C O     1 
ATOM   2073 C  CB    . LEU C 1 62  ? -6.738  -21.494 27.943  1.00 63.88  ? 62  LEU C CB    1 
ATOM   2074 C  CG    . LEU C 1 62  ? -7.478  -21.060 26.679  1.00 59.79  ? 62  LEU C CG    1 
ATOM   2075 C  CD1   . LEU C 1 62  ? -8.259  -22.213 26.061  1.00 57.98  ? 62  LEU C CD1   1 
ATOM   2076 C  CD2   . LEU C 1 62  ? -8.398  -19.903 27.009  1.00 52.57  ? 62  LEU C CD2   1 
ATOM   2077 N  N     . PRO C 1 63  ? -4.775  -21.511 30.471  1.00 68.26  ? 63  PRO C N     1 
ATOM   2078 C  CA    . PRO C 1 63  ? -4.568  -21.624 31.925  1.00 69.25  ? 63  PRO C CA    1 
ATOM   2079 C  C     . PRO C 1 63  ? -4.069  -20.346 32.571  1.00 69.96  ? 63  PRO C C     1 
ATOM   2080 O  O     . PRO C 1 63  ? -4.465  -20.048 33.704  1.00 75.74  ? 63  PRO C O     1 
ATOM   2081 C  CB    . PRO C 1 63  ? -3.540  -22.756 32.043  1.00 70.55  ? 63  PRO C CB    1 
ATOM   2082 C  CG    . PRO C 1 63  ? -3.757  -23.572 30.818  1.00 68.03  ? 63  PRO C CG    1 
ATOM   2083 C  CD    . PRO C 1 63  ? -4.068  -22.580 29.743  1.00 65.28  ? 63  PRO C CD    1 
ATOM   2084 N  N     . LEU C 1 64  ? -3.217  -19.575 31.892  1.00 73.06  ? 64  LEU C N     1 
ATOM   2085 C  CA    . LEU C 1 64  ? -2.737  -18.322 32.470  1.00 77.86  ? 64  LEU C CA    1 
ATOM   2086 C  C     . LEU C 1 64  ? -3.881  -17.329 32.654  1.00 75.89  ? 64  LEU C C     1 
ATOM   2087 O  O     . LEU C 1 64  ? -4.013  -16.707 33.716  1.00 79.17  ? 64  LEU C O     1 
ATOM   2088 C  CB    . LEU C 1 64  ? -1.636  -17.729 31.589  1.00 80.14  ? 64  LEU C CB    1 
ATOM   2089 C  CG    . LEU C 1 64  ? -0.678  -16.748 32.272  1.00 83.28  ? 64  LEU C CG    1 
ATOM   2090 C  CD1   . LEU C 1 64  ? 0.290   -17.486 33.192  1.00 85.26  ? 64  LEU C CD1   1 
ATOM   2091 C  CD2   . LEU C 1 64  ? 0.080   -15.936 31.238  1.00 82.54  ? 64  LEU C CD2   1 
ATOM   2092 N  N     . LEU C 1 65  ? -4.720  -17.170 31.624  1.00 72.97  ? 65  LEU C N     1 
ATOM   2093 C  CA    . LEU C 1 65  ? -5.866  -16.268 31.713  1.00 67.99  ? 65  LEU C CA    1 
ATOM   2094 C  C     . LEU C 1 65  ? -6.830  -16.703 32.810  1.00 70.94  ? 65  LEU C C     1 
ATOM   2095 O  O     . LEU C 1 65  ? -7.333  -15.872 33.578  1.00 74.98  ? 65  LEU C O     1 
ATOM   2096 C  CB    . LEU C 1 65  ? -6.583  -16.215 30.365  1.00 62.19  ? 65  LEU C CB    1 
ATOM   2097 C  CG    . LEU C 1 65  ? -7.603  -15.101 30.136  1.00 65.46  ? 65  LEU C CG    1 
ATOM   2098 C  CD1   . LEU C 1 65  ? -7.055  -13.754 30.606  1.00 72.15  ? 65  LEU C CD1   1 
ATOM   2099 C  CD2   . LEU C 1 65  ? -8.025  -15.042 28.673  1.00 53.34  ? 65  LEU C CD2   1 
ATOM   2100 N  N     . CYS C 1 66  ? -7.109  -18.003 32.891  1.00 69.48  ? 66  CYS C N     1 
ATOM   2101 C  CA    . CYS C 1 66  ? -7.956  -18.509 33.962  1.00 67.64  ? 66  CYS C CA    1 
ATOM   2102 C  C     . CYS C 1 66  ? -7.376  -18.173 35.326  1.00 75.35  ? 66  CYS C C     1 
ATOM   2103 O  O     . CYS C 1 66  ? -8.049  -17.570 36.167  1.00 83.89  ? 66  CYS C O     1 
ATOM   2104 C  CB    . CYS C 1 66  ? -8.137  -20.015 33.815  1.00 71.11  ? 66  CYS C CB    1 
ATOM   2105 S  SG    . CYS C 1 66  ? -8.845  -20.517 32.249  1.00 74.17  ? 66  CYS C SG    1 
ATOM   2106 N  N     . GLU C 1 67  ? -6.120  -18.547 35.565  1.00 74.45  ? 67  GLU C N     1 
ATOM   2107 C  CA    . GLU C 1 67  ? -5.542  -18.313 36.880  1.00 83.27  ? 67  GLU C CA    1 
ATOM   2108 C  C     . GLU C 1 67  ? -5.468  -16.822 37.207  1.00 82.37  ? 67  GLU C C     1 
ATOM   2109 O  O     . GLU C 1 67  ? -5.550  -16.447 38.382  1.00 83.53  ? 67  GLU C O     1 
ATOM   2110 C  CB    . GLU C 1 67  ? -4.173  -18.987 36.967  1.00 82.41  ? 67  GLU C CB    1 
ATOM   2111 C  CG    . GLU C 1 67  ? -3.704  -19.255 38.386  1.00 89.00  ? 67  GLU C CG    1 
ATOM   2112 C  CD    . GLU C 1 67  ? -2.935  -20.560 38.513  1.00 100.65 ? 67  GLU C CD    1 
ATOM   2113 O  OE1   . GLU C 1 67  ? -2.958  -21.364 37.552  1.00 91.26  ? 67  GLU C OE1   1 
ATOM   2114 O  OE2   . GLU C 1 67  ? -2.287  -20.769 39.564  1.00 111.12 ? 67  GLU C OE2   1 
ATOM   2115 N  N     . GLU C 1 68  ? -5.356  -15.954 36.193  1.00 78.63  ? 68  GLU C N     1 
ATOM   2116 C  CA    . GLU C 1 68  ? -5.419  -14.517 36.450  1.00 80.84  ? 68  GLU C CA    1 
ATOM   2117 C  C     . GLU C 1 68  ? -6.841  -14.017 36.680  1.00 84.42  ? 68  GLU C C     1 
ATOM   2118 O  O     . GLU C 1 68  ? -7.014  -12.936 37.255  1.00 84.21  ? 68  GLU C O     1 
ATOM   2119 C  CB    . GLU C 1 68  ? -4.775  -13.732 35.301  1.00 81.32  ? 68  GLU C CB    1 
ATOM   2120 C  CG    . GLU C 1 68  ? -4.424  -12.276 35.652  1.00 91.17  ? 68  GLU C CG    1 
ATOM   2121 C  CD    . GLU C 1 68  ? -3.207  -12.155 36.565  1.00 101.15 ? 68  GLU C CD    1 
ATOM   2122 O  OE1   . GLU C 1 68  ? -2.436  -13.142 36.670  1.00 98.05  ? 68  GLU C OE1   1 
ATOM   2123 O  OE2   . GLU C 1 68  ? -3.025  -11.073 37.180  1.00 93.26  ? 68  GLU C OE2   1 
ATOM   2124 N  N     . LYS C 1 69  ? -7.859  -14.762 36.241  1.00 79.58  ? 69  LYS C N     1 
ATOM   2125 C  CA    . LYS C 1 69  ? -9.245  -14.402 36.528  1.00 73.66  ? 69  LYS C CA    1 
ATOM   2126 C  C     . LYS C 1 69  ? -9.967  -15.460 37.354  1.00 73.91  ? 69  LYS C C     1 
ATOM   2127 O  O     . LYS C 1 69  ? -11.190 -15.374 37.513  1.00 75.62  ? 69  LYS C O     1 
ATOM   2128 C  CB    . LYS C 1 69  ? -10.017 -14.131 35.232  1.00 71.07  ? 69  LYS C CB    1 
ATOM   2129 C  CG    . LYS C 1 69  ? -9.199  -13.434 34.161  1.00 73.59  ? 69  LYS C CG    1 
ATOM   2130 C  CD    . LYS C 1 69  ? -10.076 -12.694 33.174  1.00 74.81  ? 69  LYS C CD    1 
ATOM   2131 C  CE    . LYS C 1 69  ? -10.872 -11.594 33.848  1.00 76.39  ? 69  LYS C CE    1 
ATOM   2132 N  NZ    . LYS C 1 69  ? -10.036 -10.382 34.095  1.00 78.94  ? 69  LYS C NZ    1 
ATOM   2133 N  N     . ASN C 1 70  ? -9.247  -16.444 37.885  1.00 78.48  ? 70  ASN C N     1 
ATOM   2134 C  CA    . ASN C 1 70  ? -9.809  -17.499 38.730  1.00 84.66  ? 70  ASN C CA    1 
ATOM   2135 C  C     . ASN C 1 70  ? -11.066 -18.117 38.117  1.00 77.94  ? 70  ASN C C     1 
ATOM   2136 O  O     . ASN C 1 70  ? -12.167 -18.042 38.666  1.00 82.02  ? 70  ASN C O     1 
ATOM   2137 C  CB    . ASN C 1 70  ? -10.102 -16.982 40.138  1.00 96.06  ? 70  ASN C CB    1 
ATOM   2138 C  CG    . ASN C 1 70  ? -9.717  -17.983 41.213  1.00 102.08 ? 70  ASN C CG    1 
ATOM   2139 O  OD1   . ASN C 1 70  ? -8.858  -18.846 41.000  1.00 91.13  ? 70  ASN C OD1   1 
ATOM   2140 N  ND2   . ASN C 1 70  ? -10.375 -17.895 42.364  1.00 109.26 ? 70  ASN C ND2   1 
ATOM   2141 N  N     . VAL C 1 71  ? -10.881 -18.743 36.964  1.00 70.93  ? 71  VAL C N     1 
ATOM   2142 C  CA    . VAL C 1 71  ? -11.908 -19.565 36.342  1.00 66.98  ? 71  VAL C CA    1 
ATOM   2143 C  C     . VAL C 1 71  ? -11.356 -20.982 36.266  1.00 66.62  ? 71  VAL C C     1 
ATOM   2144 O  O     . VAL C 1 71  ? -10.352 -21.217 35.590  1.00 71.95  ? 71  VAL C O     1 
ATOM   2145 C  CB    . VAL C 1 71  ? -12.305 -19.057 34.948  1.00 68.21  ? 71  VAL C CB    1 
ATOM   2146 C  CG1   . VAL C 1 71  ? -13.133 -20.103 34.225  1.00 67.30  ? 71  VAL C CG1   1 
ATOM   2147 C  CG2   . VAL C 1 71  ? -13.069 -17.744 35.066  1.00 68.12  ? 71  VAL C CG2   1 
ATOM   2148 N  N     . PRO C 1 72  ? -11.960 -21.949 36.945  1.00 66.28  ? 72  PRO C N     1 
ATOM   2149 C  CA    . PRO C 1 72  ? -11.377 -23.294 36.977  1.00 66.75  ? 72  PRO C CA    1 
ATOM   2150 C  C     . PRO C 1 72  ? -11.279 -23.888 35.579  1.00 69.88  ? 72  PRO C C     1 
ATOM   2151 O  O     . PRO C 1 72  ? -12.181 -23.732 34.752  1.00 69.42  ? 72  PRO C O     1 
ATOM   2152 C  CB    . PRO C 1 72  ? -12.356 -24.075 37.858  1.00 66.85  ? 72  PRO C CB    1 
ATOM   2153 C  CG    . PRO C 1 72  ? -13.652 -23.308 37.734  1.00 64.90  ? 72  PRO C CG    1 
ATOM   2154 C  CD    . PRO C 1 72  ? -13.216 -21.878 37.706  1.00 65.30  ? 72  PRO C CD    1 
ATOM   2155 N  N     . TYR C 1 73  ? -10.158 -24.556 35.314  1.00 67.19  ? 73  TYR C N     1 
ATOM   2156 C  CA    . TYR C 1 73  ? -9.936  -25.236 34.046  1.00 70.69  ? 73  TYR C CA    1 
ATOM   2157 C  C     . TYR C 1 73  ? -9.716  -26.721 34.292  1.00 73.44  ? 73  TYR C C     1 
ATOM   2158 O  O     . TYR C 1 73  ? -9.147  -27.116 35.313  1.00 74.70  ? 73  TYR C O     1 
ATOM   2159 C  CB    . TYR C 1 73  ? -8.746  -24.636 33.269  1.00 62.87  ? 73  TYR C CB    1 
ATOM   2160 C  CG    . TYR C 1 73  ? -7.486  -24.416 34.072  1.00 67.06  ? 73  TYR C CG    1 
ATOM   2161 C  CD1   . TYR C 1 73  ? -7.313  -23.258 34.811  1.00 72.02  ? 73  TYR C CD1   1 
ATOM   2162 C  CD2   . TYR C 1 73  ? -6.455  -25.343 34.060  1.00 71.79  ? 73  TYR C CD2   1 
ATOM   2163 C  CE1   . TYR C 1 73  ? -6.164  -23.037 35.538  1.00 74.10  ? 73  TYR C CE1   1 
ATOM   2164 C  CE2   . TYR C 1 73  ? -5.295  -25.129 34.787  1.00 75.92  ? 73  TYR C CE2   1 
ATOM   2165 C  CZ    . TYR C 1 73  ? -5.157  -23.973 35.525  1.00 75.74  ? 73  TYR C CZ    1 
ATOM   2166 O  OH    . TYR C 1 73  ? -4.012  -23.744 36.256  1.00 87.60  ? 73  TYR C OH    1 
ATOM   2167 N  N     . ILE C 1 74  ? -10.202 -27.537 33.356  1.00 68.66  ? 74  ILE C N     1 
ATOM   2168 C  CA    . ILE C 1 74  ? -10.009 -28.978 33.375  1.00 67.59  ? 74  ILE C CA    1 
ATOM   2169 C  C     . ILE C 1 74  ? -9.537  -29.410 31.995  1.00 69.16  ? 74  ILE C C     1 
ATOM   2170 O  O     . ILE C 1 74  ? -9.770  -28.731 30.993  1.00 64.31  ? 74  ILE C O     1 
ATOM   2171 C  CB    . ILE C 1 74  ? -11.292 -29.741 33.772  1.00 67.71  ? 74  ILE C CB    1 
ATOM   2172 C  CG1   . ILE C 1 74  ? -10.951 -31.163 34.217  1.00 76.10  ? 74  ILE C CG1   1 
ATOM   2173 C  CG2   . ILE C 1 74  ? -12.277 -29.770 32.617  1.00 69.31  ? 74  ILE C CG2   1 
ATOM   2174 C  CD1   . ILE C 1 74  ? -12.171 -32.007 34.512  1.00 88.11  ? 74  ILE C CD1   1 
ATOM   2175 N  N     . TYR C 1 75  ? -8.850  -30.546 31.958  1.00 69.47  ? 75  TYR C N     1 
ATOM   2176 C  CA    . TYR C 1 75  ? -8.266  -31.071 30.733  1.00 69.84  ? 75  TYR C CA    1 
ATOM   2177 C  C     . TYR C 1 75  ? -9.017  -32.328 30.313  1.00 75.20  ? 75  TYR C C     1 
ATOM   2178 O  O     . TYR C 1 75  ? -9.104  -33.289 31.085  1.00 81.24  ? 75  TYR C O     1 
ATOM   2179 C  CB    . TYR C 1 75  ? -6.783  -31.380 30.924  1.00 72.09  ? 75  TYR C CB    1 
ATOM   2180 C  CG    . TYR C 1 75  ? -5.886  -30.165 31.017  1.00 76.11  ? 75  TYR C CG    1 
ATOM   2181 C  CD1   . TYR C 1 75  ? -5.455  -29.506 29.871  1.00 75.15  ? 75  TYR C CD1   1 
ATOM   2182 C  CD2   . TYR C 1 75  ? -5.448  -29.692 32.248  1.00 83.09  ? 75  TYR C CD2   1 
ATOM   2183 C  CE1   . TYR C 1 75  ? -4.624  -28.400 29.950  1.00 73.75  ? 75  TYR C CE1   1 
ATOM   2184 C  CE2   . TYR C 1 75  ? -4.618  -28.589 32.337  1.00 82.44  ? 75  TYR C CE2   1 
ATOM   2185 C  CZ    . TYR C 1 75  ? -4.209  -27.948 31.185  1.00 76.64  ? 75  TYR C CZ    1 
ATOM   2186 O  OH    . TYR C 1 75  ? -3.381  -26.853 31.267  1.00 82.96  ? 75  TYR C OH    1 
ATOM   2187 N  N     . VAL C 1 76  ? -9.548  -32.318 29.096  1.00 68.54  ? 76  VAL C N     1 
ATOM   2188 C  CA    . VAL C 1 76  ? -10.134 -33.498 28.496  1.00 67.27  ? 76  VAL C CA    1 
ATOM   2189 C  C     . VAL C 1 76  ? -9.147  -34.050 27.479  1.00 73.82  ? 76  VAL C C     1 
ATOM   2190 O  O     . VAL C 1 76  ? -8.272  -33.342 26.977  1.00 74.07  ? 76  VAL C O     1 
ATOM   2191 C  CB    . VAL C 1 76  ? -11.499 -33.190 27.848  1.00 66.67  ? 76  VAL C CB    1 
ATOM   2192 C  CG1   . VAL C 1 76  ? -12.527 -32.868 28.920  1.00 69.39  ? 76  VAL C CG1   1 
ATOM   2193 C  CG2   . VAL C 1 76  ? -11.361 -32.038 26.877  1.00 69.85  ? 76  VAL C CG2   1 
ATOM   2194 N  N     . LYS C 1 77  ? -9.291  -35.336 27.165  1.00 76.73  ? 77  LYS C N     1 
ATOM   2195 C  CA    . LYS C 1 77  ? -8.343  -36.017 26.293  1.00 70.10  ? 77  LYS C CA    1 
ATOM   2196 C  C     . LYS C 1 77  ? -8.391  -35.494 24.863  1.00 68.85  ? 77  LYS C C     1 
ATOM   2197 O  O     . LYS C 1 77  ? -7.432  -34.869 24.404  1.00 72.67  ? 77  LYS C O     1 
ATOM   2198 C  CB    . LYS C 1 77  ? -8.591  -37.525 26.311  1.00 72.15  ? 77  LYS C CB    1 
ATOM   2199 C  CG    . LYS C 1 77  ? -8.368  -38.150 27.670  1.00 80.84  ? 77  LYS C CG    1 
ATOM   2200 C  CD    . LYS C 1 77  ? -6.980  -38.748 27.776  1.00 88.20  ? 77  LYS C CD    1 
ATOM   2201 C  CE    . LYS C 1 77  ? -6.656  -39.133 29.208  1.00 92.67  ? 77  LYS C CE    1 
ATOM   2202 N  NZ    . LYS C 1 77  ? -5.622  -38.220 29.785  1.00 87.29  ? 77  LYS C NZ    1 
ATOM   2203 N  N     . SER C 1 78  ? -9.484  -35.737 24.146  1.00 68.13  ? 78  SER C N     1 
ATOM   2204 C  CA    . SER C 1 78  ? -9.551  -35.402 22.731  1.00 73.48  ? 78  SER C CA    1 
ATOM   2205 C  C     . SER C 1 78  ? -10.483 -34.224 22.492  1.00 72.77  ? 78  SER C C     1 
ATOM   2206 O  O     . SER C 1 78  ? -11.367 -33.920 23.297  1.00 72.06  ? 78  SER C O     1 
ATOM   2207 C  CB    . SER C 1 78  ? -10.024 -36.592 21.891  1.00 72.69  ? 78  SER C CB    1 
ATOM   2208 O  OG    . SER C 1 78  ? -11.290 -37.047 22.329  1.00 76.41  ? 78  SER C OG    1 
ATOM   2209 N  N     . LYS C 1 79  ? -10.278 -33.572 21.347  1.00 69.53  ? 79  LYS C N     1 
ATOM   2210 C  CA    . LYS C 1 79  ? -11.139 -32.467 20.954  1.00 67.59  ? 79  LYS C CA    1 
ATOM   2211 C  C     . LYS C 1 79  ? -12.523 -32.935 20.539  1.00 71.09  ? 79  LYS C C     1 
ATOM   2212 O  O     . LYS C 1 79  ? -13.466 -32.139 20.578  1.00 72.25  ? 79  LYS C O     1 
ATOM   2213 C  CB    . LYS C 1 79  ? -10.513 -31.685 19.802  1.00 68.01  ? 79  LYS C CB    1 
ATOM   2214 C  CG    . LYS C 1 79  ? -10.000 -32.565 18.680  1.00 74.17  ? 79  LYS C CG    1 
ATOM   2215 C  CD    . LYS C 1 79  ? -9.361  -31.747 17.567  1.00 67.66  ? 79  LYS C CD    1 
ATOM   2216 C  CE    . LYS C 1 79  ? -8.022  -31.179 17.994  1.00 67.11  ? 79  LYS C CE    1 
ATOM   2217 N  NZ    . LYS C 1 79  ? -7.157  -30.986 16.804  1.00 77.23  ? 79  LYS C NZ    1 
ATOM   2218 N  N     . ASN C 1 80  ? -12.666 -34.201 20.136  1.00 71.03  ? 80  ASN C N     1 
ATOM   2219 C  CA    . ASN C 1 80  ? -13.967 -34.691 19.692  1.00 74.78  ? 80  ASN C CA    1 
ATOM   2220 C  C     . ASN C 1 80  ? -14.944 -34.804 20.858  1.00 78.17  ? 80  ASN C C     1 
ATOM   2221 O  O     . ASN C 1 80  ? -16.143 -34.527 20.701  1.00 82.81  ? 80  ASN C O     1 
ATOM   2222 C  CB    . ASN C 1 80  ? -13.802 -36.033 18.980  1.00 76.91  ? 80  ASN C CB    1 
ATOM   2223 C  CG    . ASN C 1 80  ? -13.134 -35.895 17.619  1.00 81.53  ? 80  ASN C CG    1 
ATOM   2224 O  OD1   . ASN C 1 80  ? -13.658 -35.235 16.721  1.00 82.71  ? 80  ASN C OD1   1 
ATOM   2225 N  ND2   . ASN C 1 80  ? -11.972 -36.517 17.464  1.00 77.83  ? 80  ASN C ND2   1 
ATOM   2226 N  N     . ASP C 1 81  ? -14.451 -35.205 22.035  1.00 73.63  ? 81  ASP C N     1 
ATOM   2227 C  CA    . ASP C 1 81  ? -15.306 -35.238 23.218  1.00 78.86  ? 81  ASP C CA    1 
ATOM   2228 C  C     . ASP C 1 81  ? -15.826 -33.853 23.547  1.00 78.36  ? 81  ASP C C     1 
ATOM   2229 O  O     . ASP C 1 81  ? -17.006 -33.678 23.875  1.00 82.94  ? 81  ASP C O     1 
ATOM   2230 C  CB    . ASP C 1 81  ? -14.546 -35.797 24.417  1.00 78.99  ? 81  ASP C CB    1 
ATOM   2231 C  CG    . ASP C 1 81  ? -13.770 -37.034 24.080  1.00 85.79  ? 81  ASP C CG    1 
ATOM   2232 O  OD1   . ASP C 1 81  ? -14.231 -37.792 23.199  1.00 95.29  ? 81  ASP C OD1   1 
ATOM   2233 O  OD2   . ASP C 1 81  ? -12.709 -37.255 24.707  1.00 84.06  ? 81  ASP C OD2   1 
ATOM   2234 N  N     . LEU C 1 82  ? -14.952 -32.856 23.482  1.00 75.49  ? 82  LEU C N     1 
ATOM   2235 C  CA    . LEU C 1 82  ? -15.396 -31.488 23.682  1.00 73.71  ? 82  LEU C CA    1 
ATOM   2236 C  C     . LEU C 1 82  ? -16.348 -31.055 22.581  1.00 72.04  ? 82  LEU C C     1 
ATOM   2237 O  O     . LEU C 1 82  ? -17.268 -30.267 22.821  1.00 74.51  ? 82  LEU C O     1 
ATOM   2238 C  CB    . LEU C 1 82  ? -14.185 -30.564 23.742  1.00 66.97  ? 82  LEU C CB    1 
ATOM   2239 C  CG    . LEU C 1 82  ? -14.279 -29.486 24.802  1.00 62.52  ? 82  LEU C CG    1 
ATOM   2240 C  CD1   . LEU C 1 82  ? -14.936 -30.047 26.047  1.00 61.96  ? 82  LEU C CD1   1 
ATOM   2241 C  CD2   . LEU C 1 82  ? -12.879 -29.041 25.093  1.00 58.63  ? 82  LEU C CD2   1 
ATOM   2242 N  N     . GLY C 1 83  ? -16.172 -31.611 21.387  1.00 71.05  ? 83  GLY C N     1 
ATOM   2243 C  CA    . GLY C 1 83  ? -16.892 -31.111 20.230  1.00 74.45  ? 83  GLY C CA    1 
ATOM   2244 C  C     . GLY C 1 83  ? -18.332 -31.581 20.149  1.00 77.82  ? 83  GLY C C     1 
ATOM   2245 O  O     . GLY C 1 83  ? -19.239 -30.783 19.891  1.00 77.91  ? 83  GLY C O     1 
ATOM   2246 N  N     . ARG C 1 84  ? -18.564 -32.882 20.347  1.00 82.55  ? 84  ARG C N     1 
ATOM   2247 C  CA    . ARG C 1 84  ? -19.943 -33.374 20.368  1.00 91.71  ? 84  ARG C CA    1 
ATOM   2248 C  C     . ARG C 1 84  ? -20.735 -32.807 21.542  1.00 91.53  ? 84  ARG C C     1 
ATOM   2249 O  O     . ARG C 1 84  ? -21.938 -32.542 21.414  1.00 91.34  ? 84  ARG C O     1 
ATOM   2250 C  CB    . ARG C 1 84  ? -19.956 -34.908 20.417  1.00 94.88  ? 84  ARG C CB    1 
ATOM   2251 C  CG    . ARG C 1 84  ? -21.060 -35.510 21.287  1.00 98.68  ? 84  ARG C CG    1 
ATOM   2252 C  CD    . ARG C 1 84  ? -22.358 -35.660 20.509  1.00 96.21  ? 84  ARG C CD    1 
ATOM   2253 N  NE    . ARG C 1 84  ? -23.386 -36.391 21.242  1.00 98.18  ? 84  ARG C NE    1 
ATOM   2254 C  CZ    . ARG C 1 84  ? -23.961 -35.980 22.364  1.00 100.50 ? 84  ARG C CZ    1 
ATOM   2255 N  NH1   . ARG C 1 84  ? -23.650 -34.820 22.917  1.00 101.41 ? 84  ARG C NH1   1 
ATOM   2256 N  NH2   . ARG C 1 84  ? -24.883 -36.749 22.936  1.00 100.06 ? 84  ARG C NH2   1 
ATOM   2257 N  N     . ALA C 1 85  ? -20.077 -32.599 22.683  1.00 92.95  ? 85  ALA C N     1 
ATOM   2258 C  CA    . ALA C 1 85  ? -20.770 -32.299 23.929  1.00 95.11  ? 85  ALA C CA    1 
ATOM   2259 C  C     . ALA C 1 85  ? -21.554 -30.991 23.893  1.00 92.47  ? 85  ALA C C     1 
ATOM   2260 O  O     . ALA C 1 85  ? -22.404 -30.782 24.768  1.00 94.20  ? 85  ALA C O     1 
ATOM   2261 C  CB    . ALA C 1 85  ? -19.764 -32.270 25.080  1.00 90.69  ? 85  ALA C CB    1 
ATOM   2262 N  N     . VAL C 1 86  ? -21.304 -30.116 22.916  1.00 82.25  ? 86  VAL C N     1 
ATOM   2263 C  CA    . VAL C 1 86  ? -21.940 -28.805 22.865  1.00 84.66  ? 86  VAL C CA    1 
ATOM   2264 C  C     . VAL C 1 86  ? -22.198 -28.422 21.414  1.00 83.94  ? 86  VAL C C     1 
ATOM   2265 O  O     . VAL C 1 86  ? -21.529 -28.908 20.499  1.00 80.42  ? 86  VAL C O     1 
ATOM   2266 C  CB    . VAL C 1 86  ? -21.078 -27.756 23.602  1.00 83.13  ? 86  VAL C CB    1 
ATOM   2267 C  CG1   . VAL C 1 86  ? -21.225 -27.932 25.088  1.00 81.92  ? 86  VAL C CG1   1 
ATOM   2268 C  CG2   . VAL C 1 86  ? -19.620 -27.957 23.249  1.00 72.76  ? 86  VAL C CG2   1 
ATOM   2269 N  N     . GLY C 1 87  ? -23.195 -27.559 21.213  1.00 80.60  ? 87  GLY C N     1 
ATOM   2270 C  CA    . GLY C 1 87  ? -23.734 -27.035 19.962  1.00 78.12  ? 87  GLY C CA    1 
ATOM   2271 C  C     . GLY C 1 87  ? -23.751 -28.059 18.844  1.00 76.95  ? 87  GLY C C     1 
ATOM   2272 O  O     . GLY C 1 87  ? -24.113 -29.220 19.032  1.00 80.48  ? 87  GLY C O     1 
ATOM   2273 N  N     . ARG C 1 88  ? -23.358 -27.617 17.648  1.00 78.46  ? 88  ARG C N     1 
ATOM   2274 C  CA    . ARG C 1 88  ? -23.176 -28.534 16.528  1.00 78.29  ? 88  ARG C CA    1 
ATOM   2275 C  C     . ARG C 1 88  ? -22.047 -29.502 16.829  1.00 74.84  ? 88  ARG C C     1 
ATOM   2276 O  O     . ARG C 1 88  ? -20.968 -29.102 17.275  1.00 76.69  ? 88  ARG C O     1 
ATOM   2277 C  CB    . ARG C 1 88  ? -22.871 -27.770 15.233  1.00 71.58  ? 88  ARG C CB    1 
ATOM   2278 C  CG    . ARG C 1 88  ? -22.438 -28.681 14.078  1.00 62.26  ? 88  ARG C CG    1 
ATOM   2279 C  CD    . ARG C 1 88  ? -22.266 -27.901 12.777  1.00 63.05  ? 88  ARG C CD    1 
ATOM   2280 N  NE    . ARG C 1 88  ? -21.585 -28.675 11.745  1.00 68.26  ? 88  ARG C NE    1 
ATOM   2281 C  CZ    . ARG C 1 88  ? -20.752 -28.155 10.853  1.00 64.62  ? 88  ARG C CZ    1 
ATOM   2282 N  NH1   . ARG C 1 88  ? -20.473 -26.863 10.842  1.00 62.91  ? 88  ARG C NH1   1 
ATOM   2283 N  NH2   . ARG C 1 88  ? -20.194 -28.948 9.942   1.00 64.86  ? 88  ARG C NH2   1 
ATOM   2284 N  N     . VAL C 1 89  ? -22.297 -30.779 16.580  1.00 73.78  ? 89  VAL C N     1 
ATOM   2285 C  CA    . VAL C 1 89  ? -21.258 -31.775 16.773  1.00 71.47  ? 89  VAL C CA    1 
ATOM   2286 C  C     . VAL C 1 89  ? -20.111 -31.453 15.820  1.00 66.57  ? 89  VAL C C     1 
ATOM   2287 O  O     . VAL C 1 89  ? -20.235 -31.584 14.596  1.00 66.70  ? 89  VAL C O     1 
ATOM   2288 C  CB    . VAL C 1 89  ? -21.820 -33.198 16.589  1.00 76.47  ? 89  VAL C CB    1 
ATOM   2289 C  CG1   . VAL C 1 89  ? -22.624 -33.321 15.287  1.00 83.90  ? 89  VAL C CG1   1 
ATOM   2290 C  CG2   . VAL C 1 89  ? -20.706 -34.225 16.632  1.00 88.13  ? 89  VAL C CG2   1 
ATOM   2291 N  N     . TYR C 1 90  ? -19.000 -30.980 16.383  1.00 67.03  ? 90  TYR C N     1 
ATOM   2292 C  CA    . TYR C 1 90  ? -17.838 -30.523 15.632  1.00 65.31  ? 90  TYR C CA    1 
ATOM   2293 C  C     . TYR C 1 90  ? -16.687 -30.319 16.612  1.00 65.58  ? 90  TYR C C     1 
ATOM   2294 O  O     . TYR C 1 90  ? -16.858 -29.614 17.614  1.00 68.35  ? 90  TYR C O     1 
ATOM   2295 C  CB    . TYR C 1 90  ? -18.159 -29.223 14.893  1.00 68.71  ? 90  TYR C CB    1 
ATOM   2296 C  CG    . TYR C 1 90  ? -17.152 -28.843 13.836  1.00 64.89  ? 90  TYR C CG    1 
ATOM   2297 C  CD1   . TYR C 1 90  ? -17.217 -29.389 12.570  1.00 64.61  ? 90  TYR C CD1   1 
ATOM   2298 C  CD2   . TYR C 1 90  ? -16.121 -27.965 14.113  1.00 64.11  ? 90  TYR C CD2   1 
ATOM   2299 C  CE1   . TYR C 1 90  ? -16.301 -29.053 11.604  1.00 65.59  ? 90  TYR C CE1   1 
ATOM   2300 C  CE2   . TYR C 1 90  ? -15.196 -27.625 13.150  1.00 61.47  ? 90  TYR C CE2   1 
ATOM   2301 C  CZ    . TYR C 1 90  ? -15.289 -28.176 11.899  1.00 64.99  ? 90  TYR C CZ    1 
ATOM   2302 O  OH    . TYR C 1 90  ? -14.364 -27.839 10.941  1.00 75.05  ? 90  TYR C OH    1 
ATOM   2303 N  N     . PRO C 1 91  ? -15.506 -30.881 16.347  1.00 59.23  ? 91  PRO C N     1 
ATOM   2304 C  CA    . PRO C 1 91  ? -14.429 -30.869 17.350  1.00 63.84  ? 91  PRO C CA    1 
ATOM   2305 C  C     . PRO C 1 91  ? -14.076 -29.459 17.800  1.00 65.52  ? 91  PRO C C     1 
ATOM   2306 O  O     . PRO C 1 91  ? -14.104 -28.510 17.014  1.00 65.23  ? 91  PRO C O     1 
ATOM   2307 C  CB    . PRO C 1 91  ? -13.250 -31.521 16.616  1.00 59.68  ? 91  PRO C CB    1 
ATOM   2308 C  CG    . PRO C 1 91  ? -13.610 -31.443 15.162  1.00 59.63  ? 91  PRO C CG    1 
ATOM   2309 C  CD    . PRO C 1 91  ? -15.096 -31.562 15.112  1.00 64.79  ? 91  PRO C CD    1 
ATOM   2310 N  N     . GLY C 1 92  ? -13.730 -29.333 19.080  1.00 62.92  ? 92  GLY C N     1 
ATOM   2311 C  CA    . GLY C 1 92  ? -13.357 -28.043 19.623  1.00 64.84  ? 92  GLY C CA    1 
ATOM   2312 C  C     . GLY C 1 92  ? -12.120 -28.075 20.499  1.00 61.87  ? 92  GLY C C     1 
ATOM   2313 O  O     . GLY C 1 92  ? -12.026 -28.897 21.413  1.00 68.36  ? 92  GLY C O     1 
ATOM   2314 N  N     . ALA C 1 93  ? -11.166 -27.177 20.233  1.00 58.16  ? 93  ALA C N     1 
ATOM   2315 C  CA    . ALA C 1 93  ? -9.940  -27.132 21.026  1.00 61.77  ? 93  ALA C CA    1 
ATOM   2316 C  C     . ALA C 1 93  ? -10.223 -26.778 22.477  1.00 62.38  ? 93  ALA C C     1 
ATOM   2317 O  O     . ALA C 1 93  ? -9.508  -27.224 23.381  1.00 63.89  ? 93  ALA C O     1 
ATOM   2318 C  CB    . ALA C 1 93  ? -8.962  -26.121 20.428  1.00 60.83  ? 93  ALA C CB    1 
ATOM   2319 N  N     . SER C 1 94  ? -11.250 -25.973 22.716  1.00 63.29  ? 94  SER C N     1 
ATOM   2320 C  CA    . SER C 1 94  ? -11.605 -25.574 24.064  1.00 59.57  ? 94  SER C CA    1 
ATOM   2321 C  C     . SER C 1 94  ? -13.089 -25.259 24.101  1.00 56.91  ? 94  SER C C     1 
ATOM   2322 O  O     . SER C 1 94  ? -13.741 -25.084 23.069  1.00 57.10  ? 94  SER C O     1 
ATOM   2323 C  CB    . SER C 1 94  ? -10.788 -24.367 24.534  1.00 58.27  ? 94  SER C CB    1 
ATOM   2324 O  OG    . SER C 1 94  ? -10.813 -23.328 23.571  1.00 59.84  ? 94  SER C OG    1 
ATOM   2325 N  N     . ALA C 1 95  ? -13.614 -25.207 25.311  1.00 53.45  ? 95  ALA C N     1 
ATOM   2326 C  CA    . ALA C 1 95  ? -15.013 -24.891 25.520  1.00 54.26  ? 95  ALA C CA    1 
ATOM   2327 C  C     . ALA C 1 95  ? -15.123 -24.207 26.870  1.00 58.60  ? 95  ALA C C     1 
ATOM   2328 O  O     . ALA C 1 95  ? -14.148 -24.115 27.616  1.00 62.20  ? 95  ALA C O     1 
ATOM   2329 C  CB    . ALA C 1 95  ? -15.880 -26.152 25.447  1.00 55.27  ? 95  ALA C CB    1 
ATOM   2330 N  N     . ALA C 1 96  ? -16.321 -23.740 27.198  1.00 59.56  ? 96  ALA C N     1 
ATOM   2331 C  CA    . ALA C 1 96  ? -16.514 -23.115 28.502  1.00 53.26  ? 96  ALA C CA    1 
ATOM   2332 C  C     . ALA C 1 96  ? -17.994 -23.093 28.837  1.00 57.62  ? 96  ALA C C     1 
ATOM   2333 O  O     . ALA C 1 96  ? -18.809 -22.633 28.030  1.00 60.15  ? 96  ALA C O     1 
ATOM   2334 C  CB    . ALA C 1 96  ? -15.936 -21.705 28.524  1.00 49.74  ? 96  ALA C CB    1 
ATOM   2335 N  N     . ILE C 1 97  ? -18.336 -23.602 30.016  1.00 58.63  ? 97  ILE C N     1 
ATOM   2336 C  CA    . ILE C 1 97  ? -19.643 -23.371 30.618  1.00 64.51  ? 97  ILE C CA    1 
ATOM   2337 C  C     . ILE C 1 97  ? -19.663 -21.929 31.116  1.00 63.48  ? 97  ILE C C     1 
ATOM   2338 O  O     . ILE C 1 97  ? -18.964 -21.582 32.078  1.00 61.91  ? 97  ILE C O     1 
ATOM   2339 C  CB    . ILE C 1 97  ? -19.922 -24.350 31.762  1.00 59.54  ? 97  ILE C CB    1 
ATOM   2340 C  CG1   . ILE C 1 97  ? -19.883 -25.789 31.260  1.00 55.60  ? 97  ILE C CG1   1 
ATOM   2341 C  CG2   . ILE C 1 97  ? -21.267 -24.042 32.390  1.00 57.99  ? 97  ILE C CG2   1 
ATOM   2342 C  CD1   . ILE C 1 97  ? -19.625 -26.772 32.357  1.00 59.47  ? 97  ILE C CD1   1 
ATOM   2343 N  N     . ILE C 1 98  ? -20.447 -21.083 30.438  1.00 59.62  ? 98  ILE C N     1 
ATOM   2344 C  CA    . ILE C 1 98  ? -20.605 -19.693 30.832  1.00 58.04  ? 98  ILE C CA    1 
ATOM   2345 C  C     . ILE C 1 98  ? -21.810 -19.502 31.737  1.00 60.50  ? 98  ILE C C     1 
ATOM   2346 O  O     . ILE C 1 98  ? -21.932 -18.448 32.377  1.00 65.30  ? 98  ILE C O     1 
ATOM   2347 C  CB    . ILE C 1 98  ? -20.727 -18.805 29.581  1.00 56.79  ? 98  ILE C CB    1 
ATOM   2348 C  CG1   . ILE C 1 98  ? -20.182 -17.415 29.858  1.00 66.07  ? 98  ILE C CG1   1 
ATOM   2349 C  CG2   . ILE C 1 98  ? -22.157 -18.667 29.164  1.00 56.74  ? 98  ILE C CG2   1 
ATOM   2350 C  CD1   . ILE C 1 98  ? -19.953 -16.625 28.603  1.00 75.26  ? 98  ILE C CD1   1 
ATOM   2351 N  N     . ASN C 1 99  ? -22.711 -20.482 31.805  1.00 61.83  ? 99  ASN C N     1 
ATOM   2352 C  CA    . ASN C 1 99  ? -23.785 -20.477 32.791  1.00 61.28  ? 99  ASN C CA    1 
ATOM   2353 C  C     . ASN C 1 99  ? -24.243 -21.907 33.030  1.00 63.14  ? 99  ASN C C     1 
ATOM   2354 O  O     . ASN C 1 99  ? -24.472 -22.648 32.069  1.00 60.45  ? 99  ASN C O     1 
ATOM   2355 C  CB    . ASN C 1 99  ? -24.965 -19.627 32.341  1.00 60.53  ? 99  ASN C CB    1 
ATOM   2356 C  CG    . ASN C 1 99  ? -26.111 -19.710 33.313  1.00 67.77  ? 99  ASN C CG    1 
ATOM   2357 O  OD1   . ASN C 1 99  ? -27.224 -20.097 32.960  1.00 69.36  ? 99  ASN C OD1   1 
ATOM   2358 N  ND2   . ASN C 1 99  ? -25.831 -19.385 34.569  1.00 70.87  ? 99  ASN C ND2   1 
ATOM   2359 N  N     . GLU C 1 100 ? -24.408 -22.282 34.304  1.00 63.12  ? 100 GLU C N     1 
ATOM   2360 C  CA    . GLU C 1 100 ? -24.606 -23.684 34.653  1.00 62.17  ? 100 GLU C CA    1 
ATOM   2361 C  C     . GLU C 1 100 ? -26.065 -24.114 34.664  1.00 69.64  ? 100 GLU C C     1 
ATOM   2362 O  O     . GLU C 1 100 ? -26.333 -25.317 34.729  1.00 71.05  ? 100 GLU C O     1 
ATOM   2363 C  CB    . GLU C 1 100 ? -24.013 -23.999 36.028  1.00 63.09  ? 100 GLU C CB    1 
ATOM   2364 C  CG    . GLU C 1 100 ? -24.727 -23.322 37.175  1.00 72.96  ? 100 GLU C CG    1 
ATOM   2365 C  CD    . GLU C 1 100 ? -23.868 -22.283 37.871  1.00 79.93  ? 100 GLU C CD    1 
ATOM   2366 O  OE1   . GLU C 1 100 ? -23.677 -21.185 37.303  1.00 80.40  ? 100 GLU C OE1   1 
ATOM   2367 O  OE2   . GLU C 1 100 ? -23.376 -22.575 38.985  1.00 79.96  ? 100 GLU C OE2   1 
ATOM   2368 N  N     . GLY C 1 101 ? -27.009 -23.181 34.625  1.00 72.41  ? 101 GLY C N     1 
ATOM   2369 C  CA    . GLY C 1 101 ? -28.409 -23.559 34.622  1.00 70.63  ? 101 GLY C CA    1 
ATOM   2370 C  C     . GLY C 1 101 ? -28.909 -23.968 35.990  1.00 72.87  ? 101 GLY C C     1 
ATOM   2371 O  O     . GLY C 1 101 ? -28.905 -23.165 36.929  1.00 70.36  ? 101 GLY C O     1 
ATOM   2372 N  N     . GLU C 1 102 ? -29.340 -25.221 36.120  1.00 76.43  ? 102 GLU C N     1 
ATOM   2373 C  CA    . GLU C 1 102 ? -29.750 -25.752 37.411  1.00 77.89  ? 102 GLU C CA    1 
ATOM   2374 C  C     . GLU C 1 102 ? -28.694 -26.635 38.050  1.00 74.84  ? 102 GLU C C     1 
ATOM   2375 O  O     . GLU C 1 102 ? -28.757 -26.882 39.259  1.00 74.38  ? 102 GLU C O     1 
ATOM   2376 C  CB    . GLU C 1 102 ? -31.042 -26.551 37.265  1.00 76.58  ? 102 GLU C CB    1 
ATOM   2377 C  CG    . GLU C 1 102 ? -32.194 -25.710 36.797  1.00 85.81  ? 102 GLU C CG    1 
ATOM   2378 C  CD    . GLU C 1 102 ? -33.515 -26.243 37.278  1.00 103.77 ? 102 GLU C CD    1 
ATOM   2379 O  OE1   . GLU C 1 102 ? -33.638 -26.492 38.500  1.00 104.53 ? 102 GLU C OE1   1 
ATOM   2380 O  OE2   . GLU C 1 102 ? -34.421 -26.425 36.435  1.00 115.98 ? 102 GLU C OE2   1 
ATOM   2381 N  N     . LEU C 1 103 ? -27.733 -27.107 37.266  1.00 71.32  ? 103 LEU C N     1 
ATOM   2382 C  CA    . LEU C 1 103 ? -26.671 -27.971 37.768  1.00 72.45  ? 103 LEU C CA    1 
ATOM   2383 C  C     . LEU C 1 103 ? -25.565 -27.127 38.403  1.00 74.17  ? 103 LEU C C     1 
ATOM   2384 O  O     . LEU C 1 103 ? -24.406 -27.149 37.994  1.00 73.43  ? 103 LEU C O     1 
ATOM   2385 C  CB    . LEU C 1 103 ? -26.128 -28.838 36.639  1.00 67.40  ? 103 LEU C CB    1 
ATOM   2386 C  CG    . LEU C 1 103 ? -27.171 -29.654 35.875  1.00 69.12  ? 103 LEU C CG    1 
ATOM   2387 C  CD1   . LEU C 1 103 ? -27.489 -29.028 34.522  1.00 71.26  ? 103 LEU C CD1   1 
ATOM   2388 C  CD2   . LEU C 1 103 ? -26.698 -31.079 35.699  1.00 74.68  ? 103 LEU C CD2   1 
ATOM   2389 N  N     . ARG C 1 104 ? -25.946 -26.364 39.425  1.00 73.77  ? 104 ARG C N     1 
ATOM   2390 C  CA    . ARG C 1 104 ? -24.977 -25.517 40.105  1.00 70.42  ? 104 ARG C CA    1 
ATOM   2391 C  C     . ARG C 1 104 ? -24.323 -26.214 41.287  1.00 72.49  ? 104 ARG C C     1 
ATOM   2392 O  O     . ARG C 1 104 ? -23.180 -25.896 41.633  1.00 75.49  ? 104 ARG C O     1 
ATOM   2393 C  CB    . ARG C 1 104 ? -25.639 -24.217 40.563  1.00 73.77  ? 104 ARG C CB    1 
ATOM   2394 C  CG    . ARG C 1 104 ? -26.099 -24.213 41.995  1.00 76.43  ? 104 ARG C CG    1 
ATOM   2395 C  CD    . ARG C 1 104 ? -25.873 -22.845 42.620  1.00 88.84  ? 104 ARG C CD    1 
ATOM   2396 N  NE    . ARG C 1 104 ? -26.245 -22.828 44.030  1.00 93.37  ? 104 ARG C NE    1 
ATOM   2397 C  CZ    . ARG C 1 104 ? -25.452 -23.213 45.021  1.00 90.72  ? 104 ARG C CZ    1 
ATOM   2398 N  NH1   . ARG C 1 104 ? -24.230 -23.671 44.792  1.00 88.24  ? 104 ARG C NH1   1 
ATOM   2399 N  NH2   . ARG C 1 104 ? -25.899 -23.146 46.272  1.00 91.90  ? 104 ARG C NH2   1 
ATOM   2400 N  N     . LYS C 1 105 ? -25.016 -27.173 41.900  1.00 75.45  ? 105 LYS C N     1 
ATOM   2401 C  CA    . LYS C 1 105 ? -24.420 -27.945 42.982  1.00 72.69  ? 105 LYS C CA    1 
ATOM   2402 C  C     . LYS C 1 105 ? -23.410 -28.949 42.445  1.00 72.25  ? 105 LYS C C     1 
ATOM   2403 O  O     . LYS C 1 105 ? -22.343 -29.142 43.045  1.00 73.91  ? 105 LYS C O     1 
ATOM   2404 C  CB    . LYS C 1 105 ? -25.516 -28.643 43.775  1.00 69.58  ? 105 LYS C CB    1 
ATOM   2405 C  CG    . LYS C 1 105 ? -26.682 -27.733 44.077  1.00 69.98  ? 105 LYS C CG    1 
ATOM   2406 C  CD    . LYS C 1 105 ? -27.470 -28.250 45.257  1.00 65.75  ? 105 LYS C CD    1 
ATOM   2407 C  CE    . LYS C 1 105 ? -28.877 -27.704 45.250  1.00 70.97  ? 105 LYS C CE    1 
ATOM   2408 N  NZ    . LYS C 1 105 ? -29.812 -28.762 45.706  1.00 73.15  ? 105 LYS C NZ    1 
ATOM   2409 N  N     . GLU C 1 106 ? -23.730 -29.599 41.320  1.00 69.24  ? 106 GLU C N     1 
ATOM   2410 C  CA    . GLU C 1 106 ? -22.734 -30.427 40.647  1.00 73.51  ? 106 GLU C CA    1 
ATOM   2411 C  C     . GLU C 1 106 ? -21.528 -29.594 40.248  1.00 79.93  ? 106 GLU C C     1 
ATOM   2412 O  O     . GLU C 1 106 ? -20.390 -30.070 40.309  1.00 81.75  ? 106 GLU C O     1 
ATOM   2413 C  CB    . GLU C 1 106 ? -23.325 -31.112 39.413  1.00 71.02  ? 106 GLU C CB    1 
ATOM   2414 C  CG    . GLU C 1 106 ? -24.451 -32.076 39.713  1.00 86.05  ? 106 GLU C CG    1 
ATOM   2415 C  CD    . GLU C 1 106 ? -25.824 -31.488 39.397  1.00 94.88  ? 106 GLU C CD    1 
ATOM   2416 O  OE1   . GLU C 1 106 ? -26.146 -30.390 39.920  1.00 89.56  ? 106 GLU C OE1   1 
ATOM   2417 O  OE2   . GLU C 1 106 ? -26.582 -32.142 38.636  1.00 90.74  ? 106 GLU C OE2   1 
ATOM   2418 N  N     . LEU C 1 107 ? -21.756 -28.339 39.851  1.00 84.02  ? 107 LEU C N     1 
ATOM   2419 C  CA    . LEU C 1 107 ? -20.640 -27.455 39.528  1.00 82.03  ? 107 LEU C CA    1 
ATOM   2420 C  C     . LEU C 1 107 ? -19.794 -27.157 40.757  1.00 80.97  ? 107 LEU C C     1 
ATOM   2421 O  O     . LEU C 1 107 ? -18.561 -27.142 40.677  1.00 84.58  ? 107 LEU C O     1 
ATOM   2422 C  CB    . LEU C 1 107 ? -21.149 -26.160 38.902  1.00 74.25  ? 107 LEU C CB    1 
ATOM   2423 C  CG    . LEU C 1 107 ? -20.037 -25.285 38.331  1.00 69.67  ? 107 LEU C CG    1 
ATOM   2424 C  CD1   . LEU C 1 107 ? -19.667 -25.731 36.933  1.00 74.83  ? 107 LEU C CD1   1 
ATOM   2425 C  CD2   . LEU C 1 107 ? -20.472 -23.835 38.334  1.00 73.14  ? 107 LEU C CD2   1 
ATOM   2426 N  N     . GLY C 1 108 ? -20.434 -26.902 41.900  1.00 78.67  ? 108 GLY C N     1 
ATOM   2427 C  CA    . GLY C 1 108 ? -19.668 -26.723 43.124  1.00 81.12  ? 108 GLY C CA    1 
ATOM   2428 C  C     . GLY C 1 108 ? -18.814 -27.934 43.445  1.00 83.77  ? 108 GLY C C     1 
ATOM   2429 O  O     . GLY C 1 108 ? -17.611 -27.817 43.698  1.00 85.60  ? 108 GLY C O     1 
ATOM   2430 N  N     . SER C 1 109 ? -19.426 -29.121 43.413  1.00 84.81  ? 109 SER C N     1 
ATOM   2431 C  CA    . SER C 1 109 ? -18.689 -30.348 43.706  1.00 86.29  ? 109 SER C CA    1 
ATOM   2432 C  C     . SER C 1 109 ? -17.552 -30.562 42.717  1.00 91.41  ? 109 SER C C     1 
ATOM   2433 O  O     . SER C 1 109 ? -16.469 -31.029 43.090  1.00 95.71  ? 109 SER C O     1 
ATOM   2434 C  CB    . SER C 1 109 ? -19.635 -31.548 43.690  1.00 84.00  ? 109 SER C CB    1 
ATOM   2435 O  OG    . SER C 1 109 ? -20.661 -31.399 44.656  1.00 82.99  ? 109 SER C OG    1 
ATOM   2436 N  N     . LEU C 1 110 ? -17.768 -30.191 41.453  1.00 90.42  ? 110 LEU C N     1 
ATOM   2437 C  CA    . LEU C 1 110 ? -16.757 -30.426 40.432  1.00 89.84  ? 110 LEU C CA    1 
ATOM   2438 C  C     . LEU C 1 110 ? -15.596 -29.446 40.565  1.00 91.71  ? 110 LEU C C     1 
ATOM   2439 O  O     . LEU C 1 110 ? -14.428 -29.845 40.473  1.00 95.35  ? 110 LEU C O     1 
ATOM   2440 C  CB    . LEU C 1 110 ? -17.391 -30.334 39.046  1.00 80.66  ? 110 LEU C CB    1 
ATOM   2441 C  CG    . LEU C 1 110 ? -16.490 -30.755 37.889  1.00 89.64  ? 110 LEU C CG    1 
ATOM   2442 C  CD1   . LEU C 1 110 ? -15.720 -32.017 38.266  1.00 94.59  ? 110 LEU C CD1   1 
ATOM   2443 C  CD2   . LEU C 1 110 ? -17.317 -30.988 36.634  1.00 85.33  ? 110 LEU C CD2   1 
ATOM   2444 N  N     . VAL C 1 111 ? -15.887 -28.159 40.777  1.00 89.37  ? 111 VAL C N     1 
ATOM   2445 C  CA    . VAL C 1 111 ? -14.797 -27.207 40.965  1.00 91.37  ? 111 VAL C CA    1 
ATOM   2446 C  C     . VAL C 1 111 ? -14.039 -27.515 42.246  1.00 95.40  ? 111 VAL C C     1 
ATOM   2447 O  O     . VAL C 1 111 ? -12.833 -27.273 42.323  1.00 102.39 ? 111 VAL C O     1 
ATOM   2448 C  CB    . VAL C 1 111 ? -15.288 -25.743 40.941  1.00 84.46  ? 111 VAL C CB    1 
ATOM   2449 C  CG1   . VAL C 1 111 ? -16.092 -25.459 39.684  1.00 82.14  ? 111 VAL C CG1   1 
ATOM   2450 C  CG2   . VAL C 1 111 ? -16.084 -25.398 42.191  1.00 94.66  ? 111 VAL C CG2   1 
ATOM   2451 N  N     . GLU C 1 112 ? -14.700 -28.084 43.257  1.00 95.92  ? 112 GLU C N     1 
ATOM   2452 C  CA    . GLU C 1 112 ? -13.950 -28.481 44.443  1.00 98.31  ? 112 GLU C CA    1 
ATOM   2453 C  C     . GLU C 1 112 ? -13.056 -29.680 44.145  1.00 102.98 ? 112 GLU C C     1 
ATOM   2454 O  O     . GLU C 1 112 ? -11.892 -29.714 44.568  1.00 106.12 ? 112 GLU C O     1 
ATOM   2455 C  CB    . GLU C 1 112 ? -14.898 -28.785 45.601  1.00 96.75  ? 112 GLU C CB    1 
ATOM   2456 C  CG    . GLU C 1 112 ? -15.631 -27.561 46.140  1.00 105.30 ? 112 GLU C CG    1 
ATOM   2457 C  CD    . GLU C 1 112 ? -14.827 -26.775 47.158  1.00 114.09 ? 112 GLU C CD    1 
ATOM   2458 O  OE1   . GLU C 1 112 ? -13.581 -26.874 47.139  1.00 119.62 ? 112 GLU C OE1   1 
ATOM   2459 O  OE2   . GLU C 1 112 ? -15.447 -26.068 47.986  1.00 108.45 ? 112 GLU C OE2   1 
ATOM   2460 N  N     . LYS C 1 113 ? -13.580 -30.665 43.403  1.00 103.01 ? 113 LYS C N     1 
ATOM   2461 C  CA    . LYS C 1 113 ? -12.773 -31.812 42.988  1.00 104.57 ? 113 LYS C CA    1 
ATOM   2462 C  C     . LYS C 1 113 ? -11.554 -31.381 42.181  1.00 109.51 ? 113 LYS C C     1 
ATOM   2463 O  O     . LYS C 1 113 ? -10.481 -31.987 42.289  1.00 114.03 ? 113 LYS C O     1 
ATOM   2464 C  CB    . LYS C 1 113 ? -13.624 -32.790 42.174  1.00 100.57 ? 113 LYS C CB    1 
ATOM   2465 C  CG    . LYS C 1 113 ? -14.138 -33.967 42.976  1.00 109.07 ? 113 LYS C CG    1 
ATOM   2466 C  CD    . LYS C 1 113 ? -14.970 -34.909 42.127  1.00 100.91 ? 113 LYS C CD    1 
ATOM   2467 C  CE    . LYS C 1 113 ? -16.370 -34.355 41.916  1.00 102.74 ? 113 LYS C CE    1 
ATOM   2468 N  NZ    . LYS C 1 113 ? -17.396 -35.441 41.973  1.00 109.54 ? 113 LYS C NZ    1 
ATOM   2469 N  N     . ILE C 1 114 ? -11.702 -30.347 41.351  1.00 110.01 ? 114 ILE C N     1 
ATOM   2470 C  CA    . ILE C 1 114 ? -10.564 -29.858 40.574  1.00 108.16 ? 114 ILE C CA    1 
ATOM   2471 C  C     . ILE C 1 114 ? -9.610  -29.067 41.465  1.00 109.28 ? 114 ILE C C     1 
ATOM   2472 O  O     . ILE C 1 114 ? -8.384  -29.176 41.333  1.00 112.79 ? 114 ILE C O     1 
ATOM   2473 C  CB    . ILE C 1 114 ? -11.050 -29.027 39.372  1.00 101.94 ? 114 ILE C CB    1 
ATOM   2474 C  CG1   . ILE C 1 114 ? -11.832 -29.904 38.398  1.00 95.42  ? 114 ILE C CG1   1 
ATOM   2475 C  CG2   . ILE C 1 114 ? -9.879  -28.383 38.651  1.00 97.58  ? 114 ILE C CG2   1 
ATOM   2476 C  CD1   . ILE C 1 114 ? -12.539 -29.117 37.324  1.00 88.26  ? 114 ILE C CD1   1 
ATOM   2477 N  N     . LYS C 1 115 ? -10.152 -28.267 42.392  1.00 107.21 ? 115 LYS C N     1 
ATOM   2478 C  CA    . LYS C 1 115 ? -9.315  -27.553 43.349  1.00 103.01 ? 115 LYS C CA    1 
ATOM   2479 C  C     . LYS C 1 115 ? -8.462  -28.512 44.165  1.00 111.71 ? 115 LYS C C     1 
ATOM   2480 O  O     . LYS C 1 115 ? -7.350  -28.159 44.573  1.00 119.16 ? 115 LYS C O     1 
ATOM   2481 C  CB    . LYS C 1 115 ? -10.181 -26.700 44.275  1.00 99.28  ? 115 LYS C CB    1 
ATOM   2482 C  CG    . LYS C 1 115 ? -10.492 -25.311 43.742  1.00 105.70 ? 115 LYS C CG    1 
ATOM   2483 C  CD    . LYS C 1 115 ? -11.394 -24.537 44.699  1.00 111.12 ? 115 LYS C CD    1 
ATOM   2484 C  CE    . LYS C 1 115 ? -12.115 -23.397 43.991  1.00 112.70 ? 115 LYS C CE    1 
ATOM   2485 N  NZ    . LYS C 1 115 ? -13.356 -22.991 44.707  1.00 109.12 ? 115 LYS C NZ    1 
ATOM   2486 N  N     . GLY C 1 116 ? -8.960  -29.725 44.409  1.00 114.26 ? 116 GLY C N     1 
ATOM   2487 C  CA    . GLY C 1 116 ? -8.147  -30.717 45.092  1.00 111.56 ? 116 GLY C CA    1 
ATOM   2488 C  C     . GLY C 1 116 ? -6.918  -31.116 44.296  1.00 116.61 ? 116 GLY C C     1 
ATOM   2489 O  O     . GLY C 1 116 ? -5.833  -31.286 44.858  1.00 121.25 ? 116 GLY C O     1 
ATOM   2490 N  N     . LEU C 1 117 ? -7.069  -31.263 42.981  1.00 120.32 ? 117 LEU C N     1 
ATOM   2491 C  CA    . LEU C 1 117 ? -5.974  -31.666 42.100  1.00 120.69 ? 117 LEU C CA    1 
ATOM   2492 C  C     . LEU C 1 117 ? -4.798  -30.694 42.168  1.00 125.11 ? 117 LEU C C     1 
ATOM   2493 O  O     . LEU C 1 117 ? -3.639  -31.100 42.072  1.00 122.14 ? 117 LEU C O     1 
ATOM   2494 C  CB    . LEU C 1 117 ? -6.467  -31.778 40.653  1.00 115.70 ? 117 LEU C CB    1 
ATOM   2495 C  CG    . LEU C 1 117 ? -7.437  -32.918 40.338  1.00 114.95 ? 117 LEU C CG    1 
ATOM   2496 C  CD1   . LEU C 1 117 ? -7.692  -33.028 38.838  1.00 109.19 ? 117 LEU C CD1   1 
ATOM   2497 C  CD2   . LEU C 1 117 ? -6.913  -34.232 40.893  1.00 116.37 ? 117 LEU C CD2   1 
ATOM   2498 P  P     . G   D 2 2   ? -7.036  -12.725 4.560   1.00 128.56 ? 2   G   D P     1 
ATOM   2499 O  OP1   . G   D 2 2   ? -7.012  -13.005 3.101   1.00 119.31 ? 2   G   D OP1   1 
ATOM   2500 O  OP2   . G   D 2 2   ? -6.516  -13.719 5.530   1.00 121.69 ? 2   G   D OP2   1 
ATOM   2501 O  "O5'" . G   D 2 2   ? -6.207  -11.392 4.801   1.00 132.50 ? 2   G   D "O5'" 1 
ATOM   2502 C  "C5'" . G   D 2 2   ? -4.795  -11.431 4.923   1.00 134.52 ? 2   G   D "C5'" 1 
ATOM   2503 C  "C4'" . G   D 2 2   ? -4.237  -10.041 5.039   1.00 142.72 ? 2   G   D "C4'" 1 
ATOM   2504 O  "O4'" . G   D 2 2   ? -4.757  -9.232  3.956   1.00 145.57 ? 2   G   D "O4'" 1 
ATOM   2505 C  "C3'" . G   D 2 2   ? -4.626  -9.280  6.297   1.00 144.64 ? 2   G   D "C3'" 1 
ATOM   2506 O  "O3'" . G   D 2 2   ? -3.788  -9.597  7.397   1.00 143.04 ? 2   G   D "O3'" 1 
ATOM   2507 C  "C2'" . G   D 2 2   ? -4.526  -7.821  5.862   1.00 146.58 ? 2   G   D "C2'" 1 
ATOM   2508 O  "O2'" . G   D 2 2   ? -3.184  -7.365  5.943   1.00 143.85 ? 2   G   D "O2'" 1 
ATOM   2509 C  "C1'" . G   D 2 2   ? -4.921  -7.899  4.384   1.00 146.17 ? 2   G   D "C1'" 1 
ATOM   2510 N  N9    . G   D 2 2   ? -6.307  -7.461  4.106   1.00 145.50 ? 2   G   D N9    1 
ATOM   2511 C  C8    . G   D 2 2   ? -7.251  -8.148  3.376   1.00 142.98 ? 2   G   D C8    1 
ATOM   2512 N  N7    . G   D 2 2   ? -8.385  -7.510  3.260   1.00 142.76 ? 2   G   D N7    1 
ATOM   2513 C  C5    . G   D 2 2   ? -8.178  -6.317  3.943   1.00 147.54 ? 2   G   D C5    1 
ATOM   2514 C  C6    . G   D 2 2   ? -9.054  -5.215  4.160   1.00 146.13 ? 2   G   D C6    1 
ATOM   2515 O  O6    . G   D 2 2   ? -10.224 -5.072  3.781   1.00 141.48 ? 2   G   D O6    1 
ATOM   2516 N  N1    . G   D 2 2   ? -8.444  -4.206  4.903   1.00 144.38 ? 2   G   D N1    1 
ATOM   2517 C  C2    . G   D 2 2   ? -7.154  -4.253  5.379   1.00 144.98 ? 2   G   D C2    1 
ATOM   2518 N  N2    . G   D 2 2   ? -6.730  -3.190  6.079   1.00 145.93 ? 2   G   D N2    1 
ATOM   2519 N  N3    . G   D 2 2   ? -6.329  -5.271  5.181   1.00 144.05 ? 2   G   D N3    1 
ATOM   2520 C  C4    . G   D 2 2   ? -6.897  -6.265  4.461   1.00 146.68 ? 2   G   D C4    1 
ATOM   2521 P  P     . A   D 2 3   ? -4.334  -9.493  8.906   1.00 150.27 ? 3   A   D P     1 
ATOM   2522 O  OP1   . A   D 2 3   ? -3.184  -9.664  9.830   1.00 157.88 ? 3   A   D OP1   1 
ATOM   2523 O  OP2   . A   D 2 3   ? -5.514  -10.383 9.036   1.00 140.37 ? 3   A   D OP2   1 
ATOM   2524 O  "O5'" . A   D 2 3   ? -4.817  -7.984  9.042   1.00 148.42 ? 3   A   D "O5'" 1 
ATOM   2525 C  "C5'" . A   D 2 3   ? -3.922  -6.953  9.437   1.00 148.37 ? 3   A   D "C5'" 1 
ATOM   2526 C  "C4'" . A   D 2 3   ? -4.692  -5.762  9.941   1.00 150.02 ? 3   A   D "C4'" 1 
ATOM   2527 O  "O4'" . A   D 2 3   ? -5.409  -5.158  8.833   1.00 156.21 ? 3   A   D "O4'" 1 
ATOM   2528 C  "C3'" . A   D 2 3   ? -5.774  -6.092  10.959  1.00 146.51 ? 3   A   D "C3'" 1 
ATOM   2529 O  "O3'" . A   D 2 3   ? -5.276  -6.154  12.282  1.00 148.38 ? 3   A   D "O3'" 1 
ATOM   2530 C  "C2'" . A   D 2 3   ? -6.803  -4.992  10.741  1.00 146.83 ? 3   A   D "C2'" 1 
ATOM   2531 O  "O2'" . A   D 2 3   ? -6.385  -3.785  11.366  1.00 141.37 ? 3   A   D "O2'" 1 
ATOM   2532 C  "C1'" . A   D 2 3   ? -6.715  -4.801  9.233   1.00 151.45 ? 3   A   D "C1'" 1 
ATOM   2533 N  N9    . A   D 2 3   ? -7.665  -5.642  8.471   1.00 149.24 ? 3   A   D N9    1 
ATOM   2534 C  C8    . A   D 2 3   ? -7.383  -6.834  7.844   1.00 145.77 ? 3   A   D C8    1 
ATOM   2535 N  N7    . A   D 2 3   ? -8.396  -7.361  7.200   1.00 140.93 ? 3   A   D N7    1 
ATOM   2536 C  C5    . A   D 2 3   ? -9.422  -6.450  7.405   1.00 140.09 ? 3   A   D C5    1 
ATOM   2537 C  C6    . A   D 2 3   ? -10.762 -6.434  6.976   1.00 136.96 ? 3   A   D C6    1 
ATOM   2538 N  N6    . A   D 2 3   ? -11.312 -7.395  6.229   1.00 134.71 ? 3   A   D N6    1 
ATOM   2539 N  N1    . A   D 2 3   ? -11.522 -5.382  7.348   1.00 134.28 ? 3   A   D N1    1 
ATOM   2540 C  C2    . A   D 2 3   ? -10.959 -4.425  8.098   1.00 127.97 ? 3   A   D C2    1 
ATOM   2541 N  N3    . A   D 2 3   ? -9.717  -4.323  8.566   1.00 130.80 ? 3   A   D N3    1 
ATOM   2542 C  C4    . A   D 2 3   ? -8.986  -5.383  8.179   1.00 141.00 ? 3   A   D C4    1 
ATOM   2543 P  P     . U   D 2 4   ? -4.806  -7.557  12.905  1.00 158.78 ? 4   U   D P     1 
ATOM   2544 O  OP1   . U   D 2 4   ? -3.322  -7.601  12.811  1.00 153.34 ? 4   U   D OP1   1 
ATOM   2545 O  OP2   . U   D 2 4   ? -5.596  -8.649  12.282  1.00 145.96 ? 4   U   D OP2   1 
ATOM   2546 O  "O5'" . U   D 2 4   ? -5.240  -7.447  14.436  1.00 144.67 ? 4   U   D "O5'" 1 
ATOM   2547 C  "C5'" . U   D 2 4   ? -6.588  -7.656  14.834  1.00 130.09 ? 4   U   D "C5'" 1 
ATOM   2548 C  "C4'" . U   D 2 4   ? -7.337  -6.357  15.019  1.00 125.83 ? 4   U   D "C4'" 1 
ATOM   2549 O  "O4'" . U   D 2 4   ? -7.656  -5.791  13.723  1.00 127.90 ? 4   U   D "O4'" 1 
ATOM   2550 C  "C3'" . U   D 2 4   ? -8.680  -6.484  15.725  1.00 120.87 ? 4   U   D "C3'" 1 
ATOM   2551 O  "O3'" . U   D 2 4   ? -8.541  -6.453  17.134  1.00 121.27 ? 4   U   D "O3'" 1 
ATOM   2552 C  "C2'" . U   D 2 4   ? -9.493  -5.322  15.163  1.00 115.02 ? 4   U   D "C2'" 1 
ATOM   2553 O  "O2'" . U   D 2 4   ? -9.209  -4.119  15.862  1.00 110.30 ? 4   U   D "O2'" 1 
ATOM   2554 C  "C1'" . U   D 2 4   ? -8.940  -5.205  13.741  1.00 122.46 ? 4   U   D "C1'" 1 
ATOM   2555 N  N1    . U   D 2 4   ? -9.773  -5.894  12.724  1.00 123.06 ? 4   U   D N1    1 
ATOM   2556 C  C2    . U   D 2 4   ? -10.993 -5.359  12.334  1.00 117.44 ? 4   U   D C2    1 
ATOM   2557 O  O2    . U   D 2 4   ? -11.455 -4.344  12.824  1.00 117.14 ? 4   U   D O2    1 
ATOM   2558 N  N3    . U   D 2 4   ? -11.665 -6.087  11.370  1.00 116.56 ? 4   U   D N3    1 
ATOM   2559 C  C4    . U   D 2 4   ? -11.233 -7.253  10.759  1.00 122.66 ? 4   U   D C4    1 
ATOM   2560 O  O4    . U   D 2 4   ? -11.917 -7.817  9.905   1.00 121.06 ? 4   U   D O4    1 
ATOM   2561 C  C5    . U   D 2 4   ? -9.960  -7.722  11.204  1.00 128.20 ? 4   U   D C5    1 
ATOM   2562 C  C6    . U   D 2 4   ? -9.296  -7.042  12.139  1.00 129.81 ? 4   U   D C6    1 
ATOM   2563 P  P     . G   D 2 5   ? -9.744  -6.931  18.082  1.00 126.23 ? 5   G   D P     1 
ATOM   2564 O  OP1   . G   D 2 5   ? -9.201  -7.241  19.430  1.00 118.11 ? 5   G   D OP1   1 
ATOM   2565 O  OP2   . G   D 2 5   ? -10.513 -7.961  17.339  1.00 123.87 ? 5   G   D OP2   1 
ATOM   2566 O  "O5'" . G   D 2 5   ? -10.660 -5.638  18.218  1.00 114.88 ? 5   G   D "O5'" 1 
ATOM   2567 C  "C5'" . G   D 2 5   ? -11.840 -5.680  18.999  1.00 110.90 ? 5   G   D "C5'" 1 
ATOM   2568 C  "C4'" . G   D 2 5   ? -12.999 -5.041  18.282  1.00 105.71 ? 5   G   D "C4'" 1 
ATOM   2569 O  "O4'" . G   D 2 5   ? -12.730 -4.947  16.866  1.00 102.48 ? 5   G   D "O4'" 1 
ATOM   2570 C  "C3'" . G   D 2 5   ? -14.316 -5.790  18.356  1.00 100.05 ? 5   G   D "C3'" 1 
ATOM   2571 O  "O3'" . G   D 2 5   ? -14.987 -5.552  19.577  1.00 108.75 ? 5   G   D "O3'" 1 
ATOM   2572 C  "C2'" . G   D 2 5   ? -15.080 -5.264  17.145  1.00 96.03  ? 5   G   D "C2'" 1 
ATOM   2573 O  "O2'" . G   D 2 5   ? -15.732 -4.043  17.461  1.00 96.47  ? 5   G   D "O2'" 1 
ATOM   2574 C  "C1'" . G   D 2 5   ? -13.949 -4.965  16.154  1.00 99.49  ? 5   G   D "C1'" 1 
ATOM   2575 N  N9    . G   D 2 5   ? -13.865 -5.907  15.016  1.00 100.34 ? 5   G   D N9    1 
ATOM   2576 C  C8    . G   D 2 5   ? -12.739 -6.562  14.580  1.00 102.62 ? 5   G   D C8    1 
ATOM   2577 N  N7    . G   D 2 5   ? -12.942 -7.301  13.521  1.00 99.59  ? 5   G   D N7    1 
ATOM   2578 C  C5    . G   D 2 5   ? -14.285 -7.113  13.219  1.00 96.38  ? 5   G   D C5    1 
ATOM   2579 C  C6    . G   D 2 5   ? -15.089 -7.662  12.176  1.00 89.82  ? 5   G   D C6    1 
ATOM   2580 O  O6    . G   D 2 5   ? -14.760 -8.447  11.275  1.00 89.52  ? 5   G   D O6    1 
ATOM   2581 N  N1    . G   D 2 5   ? -16.408 -7.216  12.236  1.00 83.64  ? 5   G   D N1    1 
ATOM   2582 C  C2    . G   D 2 5   ? -16.893 -6.347  13.186  1.00 86.97  ? 5   G   D C2    1 
ATOM   2583 N  N2    . G   D 2 5   ? -18.189 -6.012  13.102  1.00 81.79  ? 5   G   D N2    1 
ATOM   2584 N  N3    . G   D 2 5   ? -16.157 -5.831  14.161  1.00 92.62  ? 5   G   D N3    1 
ATOM   2585 C  C4    . G   D 2 5   ? -14.868 -6.245  14.125  1.00 96.37  ? 5   G   D C4    1 
ATOM   2586 P  P     . C   D 2 6   ? -14.888 -6.611  20.776  1.00 116.80 ? 6   C   D P     1 
ATOM   2587 O  OP1   . C   D 2 6   ? -14.579 -5.865  22.026  1.00 112.20 ? 6   C   D OP1   1 
ATOM   2588 O  OP2   . C   D 2 6   ? -13.980 -7.703  20.338  1.00 103.62 ? 6   C   D OP2   1 
ATOM   2589 O  "O5'" . C   D 2 6   ? -16.370 -7.183  20.877  1.00 100.51 ? 6   C   D "O5'" 1 
ATOM   2590 C  "C5'" . C   D 2 6   ? -16.873 -8.056  19.879  1.00 91.92  ? 6   C   D "C5'" 1 
ATOM   2591 C  "C4'" . C   D 2 6   ? -18.096 -7.506  19.188  1.00 91.21  ? 6   C   D "C4'" 1 
ATOM   2592 O  "O4'" . C   D 2 6   ? -17.724 -7.001  17.880  1.00 87.91  ? 6   C   D "O4'" 1 
ATOM   2593 C  "C3'" . C   D 2 6   ? -19.168 -8.550  18.915  1.00 92.84  ? 6   C   D "C3'" 1 
ATOM   2594 O  "O3'" . C   D 2 6   ? -20.073 -8.653  19.992  1.00 95.58  ? 6   C   D "O3'" 1 
ATOM   2595 C  "C2'" . C   D 2 6   ? -19.820 -8.088  17.620  1.00 87.56  ? 6   C   D "C2'" 1 
ATOM   2596 O  "O2'" . C   D 2 6   ? -20.823 -7.116  17.880  1.00 85.17  ? 6   C   D "O2'" 1 
ATOM   2597 C  "C1'" . C   D 2 6   ? -18.655 -7.413  16.906  1.00 83.89  ? 6   C   D "C1'" 1 
ATOM   2598 N  N1    . C   D 2 6   ? -17.938 -8.285  15.941  1.00 80.49  ? 6   C   D N1    1 
ATOM   2599 C  C2    . C   D 2 6   ? -18.532 -8.972  14.860  1.00 77.19  ? 6   C   D C2    1 
ATOM   2600 O  O2    . C   D 2 6   ? -19.760 -8.933  14.675  1.00 78.20  ? 6   C   D O2    1 
ATOM   2601 N  N3    . C   D 2 6   ? -17.728 -9.702  14.042  1.00 69.02  ? 6   C   D N3    1 
ATOM   2602 C  C4    . C   D 2 6   ? -16.410 -9.751  14.241  1.00 75.01  ? 6   C   D C4    1 
ATOM   2603 N  N4    . C   D 2 6   ? -15.640 -10.469 13.421  1.00 77.07  ? 6   C   D N4    1 
ATOM   2604 C  C5    . C   D 2 6   ? -15.793 -9.060  15.313  1.00 81.82  ? 6   C   D C5    1 
ATOM   2605 C  C6    . C   D 2 6   ? -16.585 -8.345  16.109  1.00 83.80  ? 6   C   D C6    1 
ATOM   2606 P  P     . A   D 2 7   ? -20.103 -9.986  20.872  1.00 99.01  ? 7   A   D P     1 
ATOM   2607 O  OP1   . A   D 2 7   ? -20.595 -9.629  22.229  1.00 101.04 ? 7   A   D OP1   1 
ATOM   2608 O  OP2   . A   D 2 7   ? -18.776 -10.637 20.698  1.00 90.37  ? 7   A   D OP2   1 
ATOM   2609 O  "O5'" . A   D 2 7   ? -21.205 -10.870 20.142  1.00 101.23 ? 7   A   D "O5'" 1 
ATOM   2610 C  "C5'" . A   D 2 7   ? -22.270 -10.253 19.433  1.00 94.32  ? 7   A   D "C5'" 1 
ATOM   2611 C  "C4'" . A   D 2 7   ? -22.667 -11.081 18.242  1.00 88.09  ? 7   A   D "C4'" 1 
ATOM   2612 O  "O4'" . A   D 2 7   ? -21.887 -10.701 17.083  1.00 86.80  ? 7   A   D "O4'" 1 
ATOM   2613 C  "C3'" . A   D 2 7   ? -22.392 -12.563 18.378  1.00 88.44  ? 7   A   D "C3'" 1 
ATOM   2614 O  "O3'" . A   D 2 7   ? -23.346 -13.239 19.166  1.00 89.06  ? 7   A   D "O3'" 1 
ATOM   2615 C  "C2'" . A   D 2 7   ? -22.345 -13.024 16.932  1.00 82.62  ? 7   A   D "C2'" 1 
ATOM   2616 O  "O2'" . A   D 2 7   ? -23.658 -13.147 16.402  1.00 76.10  ? 7   A   D "O2'" 1 
ATOM   2617 C  "C1'" . A   D 2 7   ? -21.662 -11.839 16.271  1.00 82.59  ? 7   A   D "C1'" 1 
ATOM   2618 N  N9    . A   D 2 7   ? -20.212 -12.041 16.106  1.00 76.45  ? 7   A   D N9    1 
ATOM   2619 C  C8    . A   D 2 7   ? -19.177 -11.571 16.876  1.00 77.73  ? 7   A   D C8    1 
ATOM   2620 N  N7    . A   D 2 7   ? -17.991 -11.906 16.420  1.00 77.31  ? 7   A   D N7    1 
ATOM   2621 C  C5    . A   D 2 7   ? -18.272 -12.645 15.278  1.00 71.79  ? 7   A   D C5    1 
ATOM   2622 C  C6    . A   D 2 7   ? -17.450 -13.287 14.335  1.00 68.03  ? 7   A   D C6    1 
ATOM   2623 N  N6    . A   D 2 7   ? -16.114 -13.287 14.398  1.00 67.32  ? 7   A   D N6    1 
ATOM   2624 N  N1    . A   D 2 7   ? -18.054 -13.937 13.312  1.00 61.83  ? 7   A   D N1    1 
ATOM   2625 C  C2    . A   D 2 7   ? -19.392 -13.933 13.246  1.00 61.40  ? 7   A   D C2    1 
ATOM   2626 N  N3    . A   D 2 7   ? -20.271 -13.368 14.070  1.00 65.50  ? 7   A   D N3    1 
ATOM   2627 C  C4    . A   D 2 7   ? -19.636 -12.736 15.075  1.00 72.39  ? 7   A   D C4    1 
ATOM   2628 P  P     . G   D 2 8   ? -22.857 -14.436 20.110  1.00 97.51  ? 8   G   D P     1 
ATOM   2629 O  OP1   . G   D 2 8   ? -24.012 -14.797 20.980  1.00 87.52  ? 8   G   D OP1   1 
ATOM   2630 O  OP2   . G   D 2 8   ? -21.544 -14.050 20.709  1.00 87.18  ? 8   G   D OP2   1 
ATOM   2631 O  "O5'" . G   D 2 8   ? -22.569 -15.610 19.071  1.00 83.91  ? 8   G   D "O5'" 1 
ATOM   2632 C  "C5'" . G   D 2 8   ? -23.491 -15.889 18.023  1.00 74.32  ? 8   G   D "C5'" 1 
ATOM   2633 C  "C4'" . G   D 2 8   ? -22.902 -16.789 16.971  1.00 70.38  ? 8   G   D "C4'" 1 
ATOM   2634 O  "O4'" . G   D 2 8   ? -21.639 -16.249 16.481  1.00 58.04  ? 8   G   D "O4'" 1 
ATOM   2635 C  "C3'" . G   D 2 8   ? -22.613 -18.207 17.453  1.00 73.60  ? 8   G   D "C3'" 1 
ATOM   2636 O  "O3'" . G   D 2 8   ? -23.072 -19.160 16.512  1.00 69.66  ? 8   G   D "O3'" 1 
ATOM   2637 C  "C2'" . G   D 2 8   ? -21.093 -18.259 17.539  1.00 78.28  ? 8   G   D "C2'" 1 
ATOM   2638 O  "O2'" . G   D 2 8   ? -20.531 -19.541 17.343  1.00 76.83  ? 8   G   D "O2'" 1 
ATOM   2639 C  "C1'" . G   D 2 8   ? -20.678 -17.280 16.451  1.00 65.08  ? 8   G   D "C1'" 1 
ATOM   2640 N  N9    . G   D 2 8   ? -19.343 -16.744 16.697  1.00 62.74  ? 8   G   D N9    1 
ATOM   2641 C  C8    . G   D 2 8   ? -18.906 -16.143 17.848  1.00 68.00  ? 8   G   D C8    1 
ATOM   2642 N  N7    . G   D 2 8   ? -17.643 -15.825 17.800  1.00 65.80  ? 8   G   D N7    1 
ATOM   2643 C  C5    . G   D 2 8   ? -17.230 -16.272 16.557  1.00 58.63  ? 8   G   D C5    1 
ATOM   2644 C  C6    . G   D 2 8   ? -15.964 -16.201 15.944  1.00 60.54  ? 8   G   D C6    1 
ATOM   2645 O  O6    . G   D 2 8   ? -14.926 -15.710 16.397  1.00 67.95  ? 8   G   D O6    1 
ATOM   2646 N  N1    . G   D 2 8   ? -15.981 -16.773 14.678  1.00 58.64  ? 8   G   D N1    1 
ATOM   2647 C  C2    . G   D 2 8   ? -17.074 -17.339 14.072  1.00 61.07  ? 8   G   D C2    1 
ATOM   2648 N  N2    . G   D 2 8   ? -16.880 -17.840 12.842  1.00 61.83  ? 8   G   D N2    1 
ATOM   2649 N  N3    . G   D 2 8   ? -18.267 -17.409 14.636  1.00 60.52  ? 8   G   D N3    1 
ATOM   2650 C  C4    . G   D 2 8   ? -18.264 -16.856 15.866  1.00 59.13  ? 8   G   D C4    1 
ATOM   2651 P  P     . A   D 2 9   ? -23.838 -20.440 17.081  1.00 75.03  ? 9   A   D P     1 
ATOM   2652 O  OP1   . A   D 2 9   ? -24.858 -19.962 18.058  1.00 70.54  ? 9   A   D OP1   1 
ATOM   2653 O  OP2   . A   D 2 9   ? -22.783 -21.394 17.511  1.00 76.48  ? 9   A   D OP2   1 
ATOM   2654 O  "O5'" . A   D 2 9   ? -24.602 -21.031 15.818  1.00 76.88  ? 9   A   D "O5'" 1 
ATOM   2655 C  "C5'" . A   D 2 9   ? -24.919 -20.214 14.698  1.00 70.29  ? 9   A   D "C5'" 1 
ATOM   2656 C  "C4'" . A   D 2 9   ? -24.821 -20.999 13.415  1.00 68.62  ? 9   A   D "C4'" 1 
ATOM   2657 O  "O4'" . A   D 2 9   ? -23.485 -20.845 12.866  1.00 72.28  ? 9   A   D "O4'" 1 
ATOM   2658 C  "C3'" . A   D 2 9   ? -25.059 -22.499 13.559  1.00 68.15  ? 9   A   D "C3'" 1 
ATOM   2659 O  "O3'" . A   D 2 9   ? -25.682 -22.981 12.372  1.00 81.27  ? 9   A   D "O3'" 1 
ATOM   2660 C  "C2'" . A   D 2 9   ? -23.643 -23.059 13.660  1.00 65.46  ? 9   A   D "C2'" 1 
ATOM   2661 O  "O2'" . A   D 2 9   ? -23.512 -24.400 13.239  1.00 64.93  ? 9   A   D "O2'" 1 
ATOM   2662 C  "C1'" . A   D 2 9   ? -22.858 -22.108 12.755  1.00 67.63  ? 9   A   D "C1'" 1 
ATOM   2663 N  N9    . A   D 2 9   ? -21.460 -21.938 13.154  1.00 65.76  ? 9   A   D N9    1 
ATOM   2664 C  C8    . A   D 2 9   ? -20.998 -21.543 14.384  1.00 67.93  ? 9   A   D C8    1 
ATOM   2665 N  N7    . A   D 2 9   ? -19.695 -21.464 14.458  1.00 65.56  ? 9   A   D N7    1 
ATOM   2666 C  C5    . A   D 2 9   ? -19.267 -21.829 13.191  1.00 63.68  ? 9   A   D C5    1 
ATOM   2667 C  C6    . A   D 2 9   ? -17.985 -21.952 12.630  1.00 62.50  ? 9   A   D C6    1 
ATOM   2668 N  N6    . A   D 2 9   ? -16.857 -21.702 13.297  1.00 55.86  ? 9   A   D N6    1 
ATOM   2669 N  N1    . A   D 2 9   ? -17.912 -22.347 11.340  1.00 63.18  ? 9   A   D N1    1 
ATOM   2670 C  C2    . A   D 2 9   ? -19.050 -22.600 10.678  1.00 61.18  ? 9   A   D C2    1 
ATOM   2671 N  N3    . A   D 2 9   ? -20.309 -22.512 11.095  1.00 56.53  ? 9   A   D N3    1 
ATOM   2672 C  C4    . A   D 2 9   ? -20.346 -22.119 12.375  1.00 58.81  ? 9   A   D C4    1 
ATOM   2673 P  P     . G   D 2 10  ? -26.818 -24.119 12.420  1.00 84.30  ? 10  G   D P     1 
ATOM   2674 O  OP1   . G   D 2 10  ? -28.065 -23.520 12.963  1.00 78.36  ? 10  G   D OP1   1 
ATOM   2675 O  OP2   . G   D 2 10  ? -26.256 -25.341 13.054  1.00 61.75  ? 10  G   D OP2   1 
ATOM   2676 O  "O5'" . G   D 2 10  ? -27.093 -24.426 10.880  1.00 76.18  ? 10  G   D "O5'" 1 
ATOM   2677 C  "C5'" . G   D 2 10  ? -26.111 -25.050 10.064  1.00 68.42  ? 10  G   D "C5'" 1 
ATOM   2678 C  "C4'" . G   D 2 10  ? -24.982 -24.110 9.731   1.00 61.89  ? 10  G   D "C4'" 1 
ATOM   2679 O  "O4'" . G   D 2 10  ? -23.721 -24.733 10.078  1.00 61.85  ? 10  G   D "O4'" 1 
ATOM   2680 C  "C3'" . G   D 2 10  ? -24.813 -23.738 8.268   1.00 66.67  ? 10  G   D "C3'" 1 
ATOM   2681 O  "O3'" . G   D 2 10  ? -25.710 -22.734 7.831   1.00 70.01  ? 10  G   D "O3'" 1 
ATOM   2682 C  "C2'" . G   D 2 10  ? -23.353 -23.321 8.210   1.00 65.15  ? 10  G   D "C2'" 1 
ATOM   2683 O  "O2'" . G   D 2 10  ? -23.181 -22.026 8.766   1.00 67.08  ? 10  G   D "O2'" 1 
ATOM   2684 C  "C1'" . G   D 2 10  ? -22.726 -24.337 9.160   1.00 62.76  ? 10  G   D "C1'" 1 
ATOM   2685 N  N9    . G   D 2 10  ? -22.250 -25.529 8.442   1.00 62.85  ? 10  G   D N9    1 
ATOM   2686 C  C8    . G   D 2 10  ? -22.740 -26.813 8.459   1.00 64.54  ? 10  G   D C8    1 
ATOM   2687 N  N7    . G   D 2 10  ? -22.063 -27.626 7.690   1.00 64.52  ? 10  G   D N7    1 
ATOM   2688 C  C5    . G   D 2 10  ? -21.074 -26.823 7.136   1.00 64.05  ? 10  G   D C5    1 
ATOM   2689 C  C6    . G   D 2 10  ? -20.027 -27.121 6.229   1.00 63.57  ? 10  G   D C6    1 
ATOM   2690 O  O6    . G   D 2 10  ? -19.749 -28.202 5.702   1.00 61.70  ? 10  G   D O6    1 
ATOM   2691 N  N1    . G   D 2 10  ? -19.257 -25.991 5.950   1.00 67.65  ? 10  G   D N1    1 
ATOM   2692 C  C2    . G   D 2 10  ? -19.470 -24.736 6.471   1.00 67.89  ? 10  G   D C2    1 
ATOM   2693 N  N2    . G   D 2 10  ? -18.643 -23.752 6.098   1.00 68.95  ? 10  G   D N2    1 
ATOM   2694 N  N3    . G   D 2 10  ? -20.438 -24.448 7.315   1.00 63.02  ? 10  G   D N3    1 
ATOM   2695 C  C4    . G   D 2 10  ? -21.184 -25.531 7.596   1.00 65.67  ? 10  G   D C4    1 
ATOM   2696 P  P     . A   D 2 11  ? -26.193 -22.699 6.298   1.00 76.41  ? 11  A   D P     1 
ATOM   2697 O  OP1   . A   D 2 11  ? -27.297 -21.706 6.221   1.00 74.57  ? 11  A   D OP1   1 
ATOM   2698 O  OP2   . A   D 2 11  ? -26.403 -24.091 5.823   1.00 80.16  ? 11  A   D OP2   1 
ATOM   2699 O  "O5'" . A   D 2 11  ? -24.936 -22.126 5.509   1.00 60.46  ? 11  A   D "O5'" 1 
ATOM   2700 C  "C5'" . A   D 2 11  ? -24.483 -20.800 5.730   1.00 66.16  ? 11  A   D "C5'" 1 
ATOM   2701 C  "C4'" . A   D 2 11  ? -23.258 -20.505 4.907   1.00 67.91  ? 11  A   D "C4'" 1 
ATOM   2702 O  "O4'" . A   D 2 11  ? -22.186 -21.393 5.305   1.00 72.34  ? 11  A   D "O4'" 1 
ATOM   2703 C  "C3'" . A   D 2 11  ? -23.398 -20.746 3.417   1.00 71.24  ? 11  A   D "C3'" 1 
ATOM   2704 O  "O3'" . A   D 2 11  ? -24.030 -19.673 2.754   1.00 78.06  ? 11  A   D "O3'" 1 
ATOM   2705 C  "C2'" . A   D 2 11  ? -21.961 -20.988 2.975   1.00 69.82  ? 11  A   D "C2'" 1 
ATOM   2706 O  "O2'" . A   D 2 11  ? -21.258 -19.762 2.842   1.00 73.57  ? 11  A   D "O2'" 1 
ATOM   2707 C  "C1'" . A   D 2 11  ? -21.401 -21.735 4.182   1.00 70.22  ? 11  A   D "C1'" 1 
ATOM   2708 N  N9    . A   D 2 11  ? -21.446 -23.197 4.010   1.00 68.14  ? 11  A   D N9    1 
ATOM   2709 C  C8    . A   D 2 11  ? -22.289 -24.098 4.613   1.00 68.89  ? 11  A   D C8    1 
ATOM   2710 N  N7    . A   D 2 11  ? -22.071 -25.341 4.265   1.00 64.89  ? 11  A   D N7    1 
ATOM   2711 C  C5    . A   D 2 11  ? -21.009 -25.244 3.378   1.00 65.69  ? 11  A   D C5    1 
ATOM   2712 C  C6    . A   D 2 11  ? -20.300 -26.207 2.649   1.00 66.76  ? 11  A   D C6    1 
ATOM   2713 N  N6    . A   D 2 11  ? -20.568 -27.510 2.709   1.00 70.00  ? 11  A   D N6    1 
ATOM   2714 N  N1    . A   D 2 11  ? -19.296 -25.785 1.851   1.00 63.77  ? 11  A   D N1    1 
ATOM   2715 C  C2    . A   D 2 11  ? -19.023 -24.477 1.796   1.00 67.47  ? 11  A   D C2    1 
ATOM   2716 N  N3    . A   D 2 11  ? -19.618 -23.470 2.432   1.00 69.23  ? 11  A   D N3    1 
ATOM   2717 C  C4    . A   D 2 11  ? -20.611 -23.932 3.213   1.00 66.60  ? 11  A   D C4    1 
ATOM   2718 P  P     . A   D 2 12  ? -24.961 -19.975 1.489   1.00 80.38  ? 12  A   D P     1 
ATOM   2719 O  OP1   . A   D 2 12  ? -25.798 -18.774 1.249   1.00 92.74  ? 12  A   D OP1   1 
ATOM   2720 O  OP2   . A   D 2 12  ? -25.632 -21.280 1.728   1.00 76.06  ? 12  A   D OP2   1 
ATOM   2721 O  "O5'" . A   D 2 12  ? -23.913 -20.116 0.295   1.00 72.80  ? 12  A   D "O5'" 1 
ATOM   2722 C  "C5'" . A   D 2 12  ? -23.055 -19.032 -0.037  1.00 75.61  ? 12  A   D "C5'" 1 
ATOM   2723 C  "C4'" . A   D 2 12  ? -21.931 -19.454 -0.954  1.00 85.13  ? 12  A   D "C4'" 1 
ATOM   2724 O  "O4'" . A   D 2 12  ? -21.064 -20.400 -0.268  1.00 86.98  ? 12  A   D "O4'" 1 
ATOM   2725 C  "C3'" . A   D 2 12  ? -22.333 -20.179 -2.233  1.00 92.46  ? 12  A   D "C3'" 1 
ATOM   2726 O  "O3'" . A   D 2 12  ? -22.775 -19.304 -3.267  1.00 95.26  ? 12  A   D "O3'" 1 
ATOM   2727 C  "C2'" . A   D 2 12  ? -21.068 -20.958 -2.578  1.00 91.47  ? 12  A   D "C2'" 1 
ATOM   2728 O  "O2'" . A   D 2 12  ? -20.095 -20.110 -3.174  1.00 89.62  ? 12  A   D "O2'" 1 
ATOM   2729 C  "C1'" . A   D 2 12  ? -20.571 -21.355 -1.186  1.00 86.51  ? 12  A   D "C1'" 1 
ATOM   2730 N  N9    . A   D 2 12  ? -21.060 -22.689 -0.785  1.00 74.92  ? 12  A   D N9    1 
ATOM   2731 C  C8    . A   D 2 12  ? -22.006 -23.006 0.160   1.00 74.60  ? 12  A   D C8    1 
ATOM   2732 N  N7    . A   D 2 12  ? -22.226 -24.296 0.283   1.00 74.55  ? 12  A   D N7    1 
ATOM   2733 C  C5    . A   D 2 12  ? -21.364 -24.871 -0.644  1.00 74.95  ? 12  A   D C5    1 
ATOM   2734 C  C6    . A   D 2 12  ? -21.108 -26.210 -1.011  1.00 76.32  ? 12  A   D C6    1 
ATOM   2735 N  N6    . A   D 2 12  ? -21.718 -27.270 -0.470  1.00 73.77  ? 12  A   D N6    1 
ATOM   2736 N  N1    . A   D 2 12  ? -20.186 -26.432 -1.974  1.00 75.81  ? 12  A   D N1    1 
ATOM   2737 C  C2    . A   D 2 12  ? -19.571 -25.375 -2.522  1.00 77.59  ? 12  A   D C2    1 
ATOM   2738 N  N3    . A   D 2 12  ? -19.722 -24.077 -2.264  1.00 74.58  ? 12  A   D N3    1 
ATOM   2739 C  C4    . A   D 2 12  ? -20.643 -23.889 -1.305  1.00 72.78  ? 12  A   D C4    1 
ATOM   2740 P  P     . C   D 2 13  ? -24.098 -19.638 -4.131  1.00 97.71  ? 13  C   D P     1 
ATOM   2741 O  OP1   . C   D 2 13  ? -24.749 -18.369 -4.540  1.00 98.03  ? 13  C   D OP1   1 
ATOM   2742 O  OP2   . C   D 2 13  ? -24.909 -20.661 -3.419  1.00 97.75  ? 13  C   D OP2   1 
ATOM   2743 O  "O5'" . C   D 2 13  ? -23.538 -20.346 -5.441  1.00 90.08  ? 13  C   D "O5'" 1 
ATOM   2744 C  "C5'" . C   D 2 13  ? -22.267 -20.013 -5.976  1.00 84.72  ? 13  C   D "C5'" 1 
ATOM   2745 C  "C4'" . C   D 2 13  ? -21.699 -21.161 -6.772  1.00 92.94  ? 13  C   D "C4'" 1 
ATOM   2746 O  "O4'" . C   D 2 13  ? -21.034 -22.101 -5.886  1.00 90.47  ? 13  C   D "O4'" 1 
ATOM   2747 C  "C3'" . C   D 2 13  ? -22.707 -22.020 -7.523  1.00 91.60  ? 13  C   D "C3'" 1 
ATOM   2748 O  "O3'" . C   D 2 13  ? -23.148 -21.442 -8.741  1.00 89.66  ? 13  C   D "O3'" 1 
ATOM   2749 C  "C2'" . C   D 2 13  ? -21.948 -23.327 -7.706  1.00 83.80  ? 13  C   D "C2'" 1 
ATOM   2750 O  "O2'" . C   D 2 13  ? -21.002 -23.207 -8.759  1.00 81.30  ? 13  C   D "O2'" 1 
ATOM   2751 C  "C1'" . C   D 2 13  ? -21.182 -23.416 -6.384  1.00 83.14  ? 13  C   D "C1'" 1 
ATOM   2752 N  N1    . C   D 2 13  ? -21.892 -24.237 -5.374  1.00 79.44  ? 13  C   D N1    1 
ATOM   2753 C  C2    . C   D 2 13  ? -21.890 -25.630 -5.511  1.00 80.76  ? 13  C   D C2    1 
ATOM   2754 O  O2    . C   D 2 13  ? -21.297 -26.153 -6.465  1.00 83.55  ? 13  C   D O2    1 
ATOM   2755 N  N3    . C   D 2 13  ? -22.531 -26.393 -4.596  1.00 80.28  ? 13  C   D N3    1 
ATOM   2756 C  C4    . C   D 2 13  ? -23.158 -25.822 -3.568  1.00 81.63  ? 13  C   D C4    1 
ATOM   2757 N  N4    . C   D 2 13  ? -23.773 -26.621 -2.691  1.00 77.38  ? 13  C   D N4    1 
ATOM   2758 C  C5    . C   D 2 13  ? -23.178 -24.406 -3.400  1.00 86.14  ? 13  C   D C5    1 
ATOM   2759 C  C6    . C   D 2 13  ? -22.537 -23.660 -4.313  1.00 82.47  ? 13  C   D C6    1 
ATOM   2760 P  P     . G   D 2 14  ? -24.700 -21.514 -9.165  1.00 93.03  ? 14  G   D P     1 
ATOM   2761 O  OP1   . G   D 2 14  ? -24.830 -20.838 -10.482 1.00 100.11 ? 14  G   D OP1   1 
ATOM   2762 O  OP2   . G   D 2 14  ? -25.547 -21.081 -8.022  1.00 92.62  ? 14  G   D OP2   1 
ATOM   2763 O  "O5'" . G   D 2 14  ? -24.971 -23.065 -9.392  1.00 90.63  ? 14  G   D "O5'" 1 
ATOM   2764 C  "C5'" . G   D 2 14  ? -24.324 -23.774 -10.438 1.00 90.90  ? 14  G   D "C5'" 1 
ATOM   2765 C  "C4'" . G   D 2 14  ? -24.574 -25.256 -10.328 1.00 93.01  ? 14  G   D "C4'" 1 
ATOM   2766 O  "O4'" . G   D 2 14  ? -23.919 -25.775 -9.138  1.00 94.08  ? 14  G   D "O4'" 1 
ATOM   2767 C  "C3'" . G   D 2 14  ? -26.027 -25.668 -10.149 1.00 96.76  ? 14  G   D "C3'" 1 
ATOM   2768 O  "O3'" . G   D 2 14  ? -26.776 -25.659 -11.353 1.00 97.91  ? 14  G   D "O3'" 1 
ATOM   2769 C  "C2'" . G   D 2 14  ? -25.899 -27.033 -9.487  1.00 87.25  ? 14  G   D "C2'" 1 
ATOM   2770 O  "O2'" . G   D 2 14  ? -25.522 -28.019 -10.435 1.00 85.94  ? 14  G   D "O2'" 1 
ATOM   2771 C  "C1'" . G   D 2 14  ? -24.716 -26.785 -8.551  1.00 87.57  ? 14  G   D "C1'" 1 
ATOM   2772 N  N9    . G   D 2 14  ? -25.180 -26.302 -7.238  1.00 88.43  ? 14  G   D N9    1 
ATOM   2773 C  C8    . G   D 2 14  ? -25.267 -24.997 -6.811  1.00 88.59  ? 14  G   D C8    1 
ATOM   2774 N  N7    . G   D 2 14  ? -25.742 -24.884 -5.601  1.00 89.74  ? 14  G   D N7    1 
ATOM   2775 C  C5    . G   D 2 14  ? -25.986 -26.195 -5.213  1.00 91.24  ? 14  G   D C5    1 
ATOM   2776 C  C6    . G   D 2 14  ? -26.503 -26.709 -3.997  1.00 91.12  ? 14  G   D C6    1 
ATOM   2777 O  O6    . G   D 2 14  ? -26.855 -26.079 -2.992  1.00 92.28  ? 14  G   D O6    1 
ATOM   2778 N  N1    . G   D 2 14  ? -26.584 -28.099 -4.027  1.00 88.14  ? 14  G   D N1    1 
ATOM   2779 C  C2    . G   D 2 14  ? -26.219 -28.889 -5.091  1.00 79.43  ? 14  G   D C2    1 
ATOM   2780 N  N2    . G   D 2 14  ? -26.375 -30.206 -4.931  1.00 80.73  ? 14  G   D N2    1 
ATOM   2781 N  N3    . G   D 2 14  ? -25.741 -28.429 -6.231  1.00 79.90  ? 14  G   D N3    1 
ATOM   2782 C  C4    . G   D 2 14  ? -25.651 -27.083 -6.215  1.00 88.86  ? 14  G   D C4    1 
ATOM   2783 P  P     . A   D 2 15  ? -27.758 -24.423 -11.676 1.00 104.59 ? 15  A   D P     1 
ATOM   2784 O  OP1   . A   D 2 15  ? -27.636 -24.082 -13.116 1.00 109.99 ? 15  A   D OP1   1 
ATOM   2785 O  OP2   . A   D 2 15  ? -27.571 -23.375 -10.641 1.00 103.71 ? 15  A   D OP2   1 
ATOM   2786 O  "O5'" . A   D 2 15  ? -29.212 -25.017 -11.447 1.00 92.71  ? 15  A   D "O5'" 1 
ATOM   2787 C  "C5'" . A   D 2 15  ? -29.590 -25.518 -10.178 1.00 91.42  ? 15  A   D "C5'" 1 
ATOM   2788 C  "C4'" . A   D 2 15  ? -30.554 -26.663 -10.322 1.00 98.63  ? 15  A   D "C4'" 1 
ATOM   2789 O  "O4'" . A   D 2 15  ? -30.519 -27.165 -11.676 1.00 104.47 ? 15  A   D "O4'" 1 
ATOM   2790 C  "C3'" . A   D 2 15  ? -30.259 -27.878 -9.465  1.00 95.40  ? 15  A   D "C3'" 1 
ATOM   2791 O  "O3'" . A   D 2 15  ? -30.760 -27.724 -8.153  1.00 89.46  ? 15  A   D "O3'" 1 
ATOM   2792 C  "C2'" . A   D 2 15  ? -30.911 -29.026 -10.234 1.00 95.72  ? 15  A   D "C2'" 1 
ATOM   2793 O  "O2'" . A   D 2 15  ? -32.286 -29.149 -9.898  1.00 84.35  ? 15  A   D "O2'" 1 
ATOM   2794 C  "C1'" . A   D 2 15  ? -30.801 -28.547 -11.683 1.00 96.02  ? 15  A   D "C1'" 1 
ATOM   2795 N  N9    . A   D 2 15  ? -29.787 -29.257 -12.491 1.00 92.68  ? 15  A   D N9    1 
ATOM   2796 C  C8    . A   D 2 15  ? -28.856 -28.677 -13.317 1.00 94.67  ? 15  A   D C8    1 
ATOM   2797 N  N7    . A   D 2 15  ? -28.100 -29.533 -13.959 1.00 95.40  ? 15  A   D N7    1 
ATOM   2798 C  C5    . A   D 2 15  ? -28.574 -30.770 -13.543 1.00 91.93  ? 15  A   D C5    1 
ATOM   2799 C  C6    . A   D 2 15  ? -28.186 -32.086 -13.863 1.00 88.75  ? 15  A   D C6    1 
ATOM   2800 N  N6    . A   D 2 15  ? -27.196 -32.380 -14.709 1.00 87.85  ? 15  A   D N6    1 
ATOM   2801 N  N1    . A   D 2 15  ? -28.857 -33.103 -13.278 1.00 88.13  ? 15  A   D N1    1 
ATOM   2802 C  C2    . A   D 2 15  ? -29.848 -32.803 -12.429 1.00 92.07  ? 15  A   D C2    1 
ATOM   2803 N  N3    . A   D 2 15  ? -30.305 -31.612 -12.046 1.00 93.52  ? 15  A   D N3    1 
ATOM   2804 C  C4    . A   D 2 15  ? -29.621 -30.618 -12.646 1.00 91.79  ? 15  A   D C4    1 
ATOM   2805 P  P     . A   D 2 16  ? -29.845 -28.126 -6.905  1.00 91.69  ? 16  A   D P     1 
ATOM   2806 O  OP1   . A   D 2 16  ? -30.653 -27.946 -5.673  1.00 94.32  ? 16  A   D OP1   1 
ATOM   2807 O  OP2   . A   D 2 16  ? -28.545 -27.420 -7.061  1.00 88.99  ? 16  A   D OP2   1 
ATOM   2808 O  "O5'" . A   D 2 16  ? -29.612 -29.687 -7.116  1.00 85.89  ? 16  A   D "O5'" 1 
ATOM   2809 C  "C5'" . A   D 2 16  ? -30.705 -30.599 -7.083  1.00 86.83  ? 16  A   D "C5'" 1 
ATOM   2810 C  "C4'" . A   D 2 16  ? -30.239 -32.023 -7.237  1.00 86.40  ? 16  A   D "C4'" 1 
ATOM   2811 O  "O4'" . A   D 2 16  ? -29.596 -32.165 -8.535  1.00 80.19  ? 16  A   D "O4'" 1 
ATOM   2812 C  "C3'" . A   D 2 16  ? -29.214 -32.469 -6.196  1.00 79.13  ? 16  A   D "C3'" 1 
ATOM   2813 O  "O3'" . A   D 2 16  ? -29.386 -33.848 -5.876  1.00 75.60  ? 16  A   D "O3'" 1 
ATOM   2814 C  "C2'" . A   D 2 16  ? -27.895 -32.274 -6.923  1.00 88.91  ? 16  A   D "C2'" 1 
ATOM   2815 O  "O2'" . A   D 2 16  ? -26.830 -33.069 -6.453  1.00 87.85  ? 16  A   D "O2'" 1 
ATOM   2816 C  "C1'" . A   D 2 16  ? -28.268 -32.612 -8.363  1.00 83.48  ? 16  A   D "C1'" 1 
ATOM   2817 N  N9    . A   D 2 16  ? -27.400 -31.922 -9.316  1.00 84.36  ? 16  A   D N9    1 
ATOM   2818 C  C8    . A   D 2 16  ? -27.134 -30.576 -9.376  1.00 85.88  ? 16  A   D C8    1 
ATOM   2819 N  N7    . A   D 2 16  ? -26.272 -30.245 -10.309 1.00 87.54  ? 16  A   D N7    1 
ATOM   2820 C  C5    . A   D 2 16  ? -25.933 -31.464 -10.891 1.00 88.87  ? 16  A   D C5    1 
ATOM   2821 C  C6    . A   D 2 16  ? -25.059 -31.811 -11.945 1.00 84.38  ? 16  A   D C6    1 
ATOM   2822 N  N6    . A   D 2 16  ? -24.329 -30.935 -12.641 1.00 84.87  ? 16  A   D N6    1 
ATOM   2823 N  N1    . A   D 2 16  ? -24.957 -33.119 -12.272 1.00 84.04  ? 16  A   D N1    1 
ATOM   2824 C  C2    . A   D 2 16  ? -25.684 -34.009 -11.583 1.00 84.47  ? 16  A   D C2    1 
ATOM   2825 N  N3    . A   D 2 16  ? -26.534 -33.812 -10.576 1.00 87.08  ? 16  A   D N3    1 
ATOM   2826 C  C4    . A   D 2 16  ? -26.616 -32.505 -10.278 1.00 89.10  ? 16  A   D C4    1 
ATOM   2827 P  P     . A   D 2 17  ? -28.579 -34.503 -4.643  1.00 87.09  ? 17  A   D P     1 
ATOM   2828 O  OP1   . A   D 2 17  ? -29.428 -35.571 -4.053  1.00 96.88  ? 17  A   D OP1   1 
ATOM   2829 O  OP2   . A   D 2 17  ? -27.999 -33.431 -3.797  1.00 78.10  ? 17  A   D OP2   1 
ATOM   2830 O  "O5'" . A   D 2 17  ? -27.346 -35.215 -5.349  1.00 90.72  ? 17  A   D "O5'" 1 
ATOM   2831 C  "C5'" . A   D 2 17  ? -27.574 -36.143 -6.394  1.00 86.69  ? 17  A   D "C5'" 1 
ATOM   2832 C  "C4'" . A   D 2 17  ? -26.295 -36.662 -7.001  1.00 79.54  ? 17  A   D "C4'" 1 
ATOM   2833 O  "O4'" . A   D 2 17  ? -25.917 -35.900 -8.171  1.00 83.76  ? 17  A   D "O4'" 1 
ATOM   2834 C  "C3'" . A   D 2 17  ? -25.031 -36.642 -6.160  1.00 70.32  ? 17  A   D "C3'" 1 
ATOM   2835 O  "O3'" . A   D 2 17  ? -25.013 -37.628 -5.138  1.00 75.80  ? 17  A   D "O3'" 1 
ATOM   2836 C  "C2'" . A   D 2 17  ? -23.949 -36.855 -7.218  1.00 77.09  ? 17  A   D "C2'" 1 
ATOM   2837 O  "O2'" . A   D 2 17  ? -23.825 -38.237 -7.521  1.00 81.36  ? 17  A   D "O2'" 1 
ATOM   2838 C  "C1'" . A   D 2 17  ? -24.553 -36.149 -8.443  1.00 84.00  ? 17  A   D "C1'" 1 
ATOM   2839 N  N9    . A   D 2 17  ? -23.830 -34.930 -8.887  1.00 84.67  ? 17  A   D N9    1 
ATOM   2840 C  C8    . A   D 2 17  ? -22.845 -34.947 -9.855  1.00 86.98  ? 17  A   D C8    1 
ATOM   2841 N  N7    . A   D 2 17  ? -22.316 -33.784 -10.138 1.00 78.60  ? 17  A   D N7    1 
ATOM   2842 C  C5    . A   D 2 17  ? -22.996 -32.920 -9.297  1.00 78.79  ? 17  A   D C5    1 
ATOM   2843 C  C6    . A   D 2 17  ? -22.887 -31.529 -9.121  1.00 78.64  ? 17  A   D C6    1 
ATOM   2844 N  N6    . A   D 2 17  ? -22.036 -30.761 -9.800  1.00 73.33  ? 17  A   D N6    1 
ATOM   2845 N  N1    . A   D 2 17  ? -23.695 -30.949 -8.211  1.00 84.90  ? 17  A   D N1    1 
ATOM   2846 C  C2    . A   D 2 17  ? -24.540 -31.740 -7.541  1.00 83.39  ? 17  A   D C2    1 
ATOM   2847 N  N3    . A   D 2 17  ? -24.748 -33.056 -7.610  1.00 75.60  ? 17  A   D N3    1 
ATOM   2848 C  C4    . A   D 2 17  ? -23.931 -33.605 -8.519  1.00 78.97  ? 17  A   D C4    1 
ATOM   2849 P  P     . G   D 2 18  ? -23.964 -37.514 -3.920  1.00 82.98  ? 18  G   D P     1 
ATOM   2850 O  OP1   . G   D 2 18  ? -24.186 -38.656 -2.995  1.00 69.42  ? 18  G   D OP1   1 
ATOM   2851 O  OP2   . G   D 2 18  ? -24.059 -36.132 -3.389  1.00 77.57  ? 18  G   D OP2   1 
ATOM   2852 O  "O5'" . G   D 2 18  ? -22.535 -37.703 -4.611  1.00 78.69  ? 18  G   D "O5'" 1 
ATOM   2853 C  "C5'" . G   D 2 18  ? -21.382 -36.991 -4.168  1.00 71.63  ? 18  G   D "C5'" 1 
ATOM   2854 C  "C4'" . G   D 2 18  ? -20.740 -36.210 -5.290  1.00 67.58  ? 18  G   D "C4'" 1 
ATOM   2855 O  "O4'" . G   D 2 18  ? -21.750 -35.373 -5.898  1.00 69.22  ? 18  G   D "O4'" 1 
ATOM   2856 C  "C3'" . G   D 2 18  ? -19.634 -35.248 -4.875  1.00 74.12  ? 18  G   D "C3'" 1 
ATOM   2857 O  "O3'" . G   D 2 18  ? -18.363 -35.872 -4.854  1.00 81.16  ? 18  G   D "O3'" 1 
ATOM   2858 C  "C2'" . G   D 2 18  ? -19.736 -34.129 -5.905  1.00 72.25  ? 18  G   D "C2'" 1 
ATOM   2859 O  "O2'" . G   D 2 18  ? -19.068 -34.484 -7.105  1.00 72.98  ? 18  G   D "O2'" 1 
ATOM   2860 C  "C1'" . G   D 2 18  ? -21.234 -34.101 -6.187  1.00 69.05  ? 18  G   D "C1'" 1 
ATOM   2861 N  N9    . G   D 2 18  ? -21.964 -33.142 -5.343  1.00 71.73  ? 18  G   D N9    1 
ATOM   2862 C  C8    . G   D 2 18  ? -22.959 -33.495 -4.465  1.00 73.17  ? 18  G   D C8    1 
ATOM   2863 N  N7    . G   D 2 18  ? -23.483 -32.484 -3.840  1.00 72.00  ? 18  G   D N7    1 
ATOM   2864 C  C5    . G   D 2 18  ? -22.790 -31.394 -4.345  1.00 71.54  ? 18  G   D C5    1 
ATOM   2865 C  C6    . G   D 2 18  ? -22.934 -30.021 -4.036  1.00 76.29  ? 18  G   D C6    1 
ATOM   2866 O  O6    . G   D 2 18  ? -23.715 -29.494 -3.233  1.00 86.76  ? 18  G   D O6    1 
ATOM   2867 N  N1    . G   D 2 18  ? -22.048 -29.238 -4.760  1.00 74.79  ? 18  G   D N1    1 
ATOM   2868 C  C2    . G   D 2 18  ? -21.137 -29.705 -5.675  1.00 74.60  ? 18  G   D C2    1 
ATOM   2869 N  N2    . G   D 2 18  ? -20.380 -28.766 -6.263  1.00 71.27  ? 18  G   D N2    1 
ATOM   2870 N  N3    . G   D 2 18  ? -20.995 -30.990 -5.980  1.00 75.36  ? 18  G   D N3    1 
ATOM   2871 C  C4    . G   D 2 18  ? -21.852 -31.773 -5.283  1.00 72.83  ? 18  G   D C4    1 
ATOM   2872 P  P     . U   D 2 19  ? -17.254 -35.424 -3.784  1.00 80.12  ? 19  U   D P     1 
ATOM   2873 O  OP1   . U   D 2 19  ? -16.073 -36.306 -3.949  1.00 74.06  ? 19  U   D OP1   1 
ATOM   2874 O  OP2   . U   D 2 19  ? -17.928 -35.286 -2.470  1.00 75.04  ? 19  U   D OP2   1 
ATOM   2875 O  "O5'" . U   D 2 19  ? -16.814 -33.971 -4.252  1.00 62.56  ? 19  U   D "O5'" 1 
ATOM   2876 C  "C5'" . U   D 2 19  ? -15.979 -33.789 -5.383  1.00 64.38  ? 19  U   D "C5'" 1 
ATOM   2877 C  "C4'" . U   D 2 19  ? -15.611 -32.339 -5.532  1.00 66.24  ? 19  U   D "C4'" 1 
ATOM   2878 O  "O4'" . U   D 2 19  ? -16.810 -31.571 -5.820  1.00 69.99  ? 19  U   D "O4'" 1 
ATOM   2879 C  "C3'" . U   D 2 19  ? -15.046 -31.688 -4.280  1.00 71.73  ? 19  U   D "C3'" 1 
ATOM   2880 O  "O3'" . U   D 2 19  ? -13.660 -31.951 -4.102  1.00 66.38  ? 19  U   D "O3'" 1 
ATOM   2881 C  "C2'" . U   D 2 19  ? -15.388 -30.216 -4.489  1.00 69.76  ? 19  U   D "C2'" 1 
ATOM   2882 O  "O2'" . U   D 2 19  ? -14.481 -29.625 -5.405  1.00 75.47  ? 19  U   D "O2'" 1 
ATOM   2883 C  "C1'" . U   D 2 19  ? -16.748 -30.314 -5.179  1.00 65.30  ? 19  U   D "C1'" 1 
ATOM   2884 N  N1    . U   D 2 19  ? -17.895 -30.205 -4.242  1.00 69.73  ? 19  U   D N1    1 
ATOM   2885 C  C2    . U   D 2 19  ? -18.312 -28.957 -3.805  1.00 69.34  ? 19  U   D C2    1 
ATOM   2886 O  O2    . U   D 2 19  ? -17.771 -27.918 -4.133  1.00 67.78  ? 19  U   D O2    1 
ATOM   2887 N  N3    . U   D 2 19  ? -19.391 -28.965 -2.953  1.00 70.20  ? 19  U   D N3    1 
ATOM   2888 C  C4    . U   D 2 19  ? -20.091 -30.067 -2.504  1.00 69.10  ? 19  U   D C4    1 
ATOM   2889 O  O4    . U   D 2 19  ? -21.045 -29.922 -1.738  1.00 76.11  ? 19  U   D O4    1 
ATOM   2890 C  C5    . U   D 2 19  ? -19.608 -31.312 -3.003  1.00 65.69  ? 19  U   D C5    1 
ATOM   2891 C  C6    . U   D 2 19  ? -18.564 -31.334 -3.832  1.00 67.75  ? 19  U   D C6    1 
ATOM   2892 P  P     . U   D 2 20  ? -13.008 -32.025 -2.631  1.00 79.20  ? 20  U   D P     1 
ATOM   2893 O  OP1   . U   D 2 20  ? -11.583 -32.379 -2.853  1.00 78.03  ? 20  U   D OP1   1 
ATOM   2894 O  OP2   . U   D 2 20  ? -13.800 -32.901 -1.708  1.00 69.81  ? 20  U   D OP2   1 
ATOM   2895 O  "O5'" . U   D 2 20  ? -13.059 -30.508 -2.139  1.00 67.15  ? 20  U   D "O5'" 1 
ATOM   2896 C  "C5'" . U   D 2 20  ? -12.346 -29.497 -2.840  1.00 62.27  ? 20  U   D "C5'" 1 
ATOM   2897 C  "C4'" . U   D 2 20  ? -12.740 -28.100 -2.411  1.00 68.38  ? 20  U   D "C4'" 1 
ATOM   2898 O  "O4'" . U   D 2 20  ? -14.138 -27.856 -2.701  1.00 66.05  ? 20  U   D "O4'" 1 
ATOM   2899 C  "C3'" . U   D 2 20  ? -12.614 -27.781 -0.930  1.00 67.91  ? 20  U   D "C3'" 1 
ATOM   2900 O  "O3'" . U   D 2 20  ? -11.289 -27.492 -0.527  1.00 62.34  ? 20  U   D "O3'" 1 
ATOM   2901 C  "C2'" . U   D 2 20  ? -13.573 -26.610 -0.754  1.00 66.23  ? 20  U   D "C2'" 1 
ATOM   2902 O  "O2'" . U   D 2 20  ? -12.973 -25.392 -1.164  1.00 68.00  ? 20  U   D "O2'" 1 
ATOM   2903 C  "C1'" . U   D 2 20  ? -14.681 -26.971 -1.741  1.00 67.15  ? 20  U   D "C1'" 1 
ATOM   2904 N  N1    . U   D 2 20  ? -15.818 -27.630 -1.063  1.00 71.24  ? 20  U   D N1    1 
ATOM   2905 C  C2    . U   D 2 20  ? -16.716 -26.803 -0.416  1.00 68.67  ? 20  U   D C2    1 
ATOM   2906 O  O2    . U   D 2 20  ? -16.602 -25.591 -0.390  1.00 69.35  ? 20  U   D O2    1 
ATOM   2907 N  N3    . U   D 2 20  ? -17.757 -27.443 0.203   1.00 68.67  ? 20  U   D N3    1 
ATOM   2908 C  C4    . U   D 2 20  ? -17.979 -28.807 0.243   1.00 70.36  ? 20  U   D C4    1 
ATOM   2909 O  O4    . U   D 2 20  ? -18.963 -29.243 0.846   1.00 70.54  ? 20  U   D O4    1 
ATOM   2910 C  C5    . U   D 2 20  ? -17.001 -29.597 -0.445  1.00 66.91  ? 20  U   D C5    1 
ATOM   2911 C  C6    . U   D 2 20  ? -15.978 -28.997 -1.060  1.00 68.49  ? 20  U   D C6    1 
ATOM   2912 P  P     . C   D 2 21  ? -10.840 -27.804 0.981   1.00 91.41  ? 21  C   D P     1 
ATOM   2913 O  OP1   . C   D 2 21  ? -9.368  -27.599 1.094   1.00 87.72  ? 21  C   D OP1   1 
ATOM   2914 O  OP2   . C   D 2 21  ? -11.461 -29.099 1.374   1.00 73.44  ? 21  C   D OP2   1 
ATOM   2915 O  "O5'" . C   D 2 21  ? -11.545 -26.653 1.823   1.00 77.30  ? 21  C   D "O5'" 1 
ATOM   2916 C  "C5'" . C   D 2 21  ? -11.121 -25.305 1.702   1.00 66.23  ? 21  C   D "C5'" 1 
ATOM   2917 C  "C4'" . C   D 2 21  ? -11.986 -24.383 2.522   1.00 66.07  ? 21  C   D "C4'" 1 
ATOM   2918 O  "O4'" . C   D 2 21  ? -13.339 -24.373 1.996   1.00 66.66  ? 21  C   D "O4'" 1 
ATOM   2919 C  "C3'" . C   D 2 21  ? -12.176 -24.759 3.982   1.00 67.99  ? 21  C   D "C3'" 1 
ATOM   2920 O  "O3'" . C   D 2 21  ? -11.070 -24.433 4.804   1.00 67.82  ? 21  C   D "O3'" 1 
ATOM   2921 C  "C2'" . C   D 2 21  ? -13.455 -24.016 4.340   1.00 66.70  ? 21  C   D "C2'" 1 
ATOM   2922 O  "O2'" . C   D 2 21  ? -13.201 -22.634 4.542   1.00 72.31  ? 21  C   D "O2'" 1 
ATOM   2923 C  "C1'" . C   D 2 21  ? -14.260 -24.179 3.052   1.00 63.65  ? 21  C   D "C1'" 1 
ATOM   2924 N  N1    . C   D 2 21  ? -15.159 -25.350 3.141   1.00 65.39  ? 21  C   D N1    1 
ATOM   2925 C  C2    . C   D 2 21  ? -16.324 -25.204 3.896   1.00 65.00  ? 21  C   D C2    1 
ATOM   2926 O  O2    . C   D 2 21  ? -16.548 -24.105 4.422   1.00 64.44  ? 21  C   D O2    1 
ATOM   2927 N  N3    . C   D 2 21  ? -17.167 -26.255 4.019   1.00 69.13  ? 21  C   D N3    1 
ATOM   2928 C  C4    . C   D 2 21  ? -16.876 -27.417 3.430   1.00 69.38  ? 21  C   D C4    1 
ATOM   2929 N  N4    . C   D 2 21  ? -17.738 -28.426 3.576   1.00 67.91  ? 21  C   D N4    1 
ATOM   2930 C  C5    . C   D 2 21  ? -15.689 -27.596 2.661   1.00 67.27  ? 21  C   D C5    1 
ATOM   2931 C  C6    . C   D 2 21  ? -14.864 -26.546 2.548   1.00 69.82  ? 21  C   D C6    1 
ATOM   2932 P  P     . C   D 2 22  ? -10.776 -25.295 6.128   1.00 69.35  ? 22  C   D P     1 
ATOM   2933 O  OP1   . C   D 2 22  ? -9.544  -24.757 6.760   1.00 70.14  ? 22  C   D OP1   1 
ATOM   2934 O  OP2   . C   D 2 22  ? -10.825 -26.741 5.765   1.00 61.72  ? 22  C   D OP2   1 
ATOM   2935 O  "O5'" . C   D 2 22  ? -11.999 -24.934 7.088   1.00 62.26  ? 22  C   D "O5'" 1 
ATOM   2936 C  "C5'" . C   D 2 22  ? -12.189 -23.599 7.538   1.00 61.83  ? 22  C   D "C5'" 1 
ATOM   2937 C  "C4'" . C   D 2 22  ? -13.413 -23.453 8.411   1.00 59.92  ? 22  C   D "C4'" 1 
ATOM   2938 O  "O4'" . C   D 2 22  ? -14.607 -23.823 7.675   1.00 62.23  ? 22  C   D "O4'" 1 
ATOM   2939 C  "C3'" . C   D 2 22  ? -13.472 -24.331 9.647   1.00 61.43  ? 22  C   D "C3'" 1 
ATOM   2940 O  "O3'" . C   D 2 22  ? -12.667 -23.866 10.711  1.00 64.42  ? 22  C   D "O3'" 1 
ATOM   2941 C  "C2'" . C   D 2 22  ? -14.959 -24.341 9.966   1.00 62.89  ? 22  C   D "C2'" 1 
ATOM   2942 O  "O2'" . C   D 2 22  ? -15.349 -23.126 10.587  1.00 68.62  ? 22  C   D "O2'" 1 
ATOM   2943 C  "C1'" . C   D 2 22  ? -15.561 -24.375 8.562   1.00 64.06  ? 22  C   D "C1'" 1 
ATOM   2944 N  N1    . C   D 2 22  ? -15.881 -25.760 8.141   1.00 63.58  ? 22  C   D N1    1 
ATOM   2945 C  C2    . C   D 2 22  ? -17.076 -26.339 8.592   1.00 66.31  ? 22  C   D C2    1 
ATOM   2946 O  O2    . C   D 2 22  ? -17.836 -25.680 9.318   1.00 70.54  ? 22  C   D O2    1 
ATOM   2947 N  N3    . C   D 2 22  ? -17.383 -27.602 8.229   1.00 64.75  ? 22  C   D N3    1 
ATOM   2948 C  C4    . C   D 2 22  ? -16.556 -28.287 7.447   1.00 66.07  ? 22  C   D C4    1 
ATOM   2949 N  N4    . C   D 2 22  ? -16.912 -29.531 7.111   1.00 68.32  ? 22  C   D N4    1 
ATOM   2950 C  C5    . C   D 2 22  ? -15.334 -27.730 6.972   1.00 60.59  ? 22  C   D C5    1 
ATOM   2951 C  C6    . C   D 2 22  ? -15.036 -26.480 7.342   1.00 58.24  ? 22  C   D C6    1 
ATOM   2952 P  P     . A   D 2 23  ? -11.874 -24.927 11.618  1.00 69.26  ? 23  A   D P     1 
ATOM   2953 O  OP1   . A   D 2 23  ? -10.431 -24.756 11.320  1.00 76.74  ? 23  A   D OP1   1 
ATOM   2954 O  OP2   . A   D 2 23  ? -12.502 -26.258 11.432  1.00 66.56  ? 23  A   D OP2   1 
ATOM   2955 O  "O5'" . A   D 2 23  ? -12.133 -24.456 13.119  1.00 61.69  ? 23  A   D "O5'" 1 
ATOM   2956 C  "C5'" . A   D 2 23  ? -13.449 -24.189 13.595  1.00 62.49  ? 23  A   D "C5'" 1 
ATOM   2957 C  "C4'" . A   D 2 23  ? -13.433 -23.589 14.980  1.00 59.44  ? 23  A   D "C4'" 1 
ATOM   2958 O  "O4'" . A   D 2 23  ? -14.754 -23.067 15.295  1.00 63.79  ? 23  A   D "O4'" 1 
ATOM   2959 C  "C3'" . A   D 2 23  ? -13.085 -24.561 16.103  1.00 56.30  ? 23  A   D "C3'" 1 
ATOM   2960 O  "O3'" . A   D 2 23  ? -12.394 -23.850 17.130  1.00 53.09  ? 23  A   D "O3'" 1 
ATOM   2961 C  "C2'" . A   D 2 23  ? -14.460 -24.981 16.612  1.00 55.21  ? 23  A   D "C2'" 1 
ATOM   2962 O  "O2'" . A   D 2 23  ? -14.477 -25.457 17.939  1.00 61.06  ? 23  A   D "O2'" 1 
ATOM   2963 C  "C1'" . A   D 2 23  ? -15.236 -23.676 16.477  1.00 58.96  ? 23  A   D "C1'" 1 
ATOM   2964 N  N9    . A   D 2 23  ? -16.687 -23.835 16.355  1.00 57.92  ? 23  A   D N9    1 
ATOM   2965 C  C8    . A   D 2 23  ? -17.635 -23.497 17.285  1.00 60.39  ? 23  A   D C8    1 
ATOM   2966 N  N7    . A   D 2 23  ? -18.861 -23.746 16.896  1.00 60.62  ? 23  A   D N7    1 
ATOM   2967 C  C5    . A   D 2 23  ? -18.711 -24.281 15.630  1.00 55.62  ? 23  A   D C5    1 
ATOM   2968 C  C6    . A   D 2 23  ? -19.642 -24.749 14.695  1.00 58.59  ? 23  A   D C6    1 
ATOM   2969 N  N6    . A   D 2 23  ? -20.961 -24.752 14.906  1.00 64.18  ? 23  A   D N6    1 
ATOM   2970 N  N1    . A   D 2 23  ? -19.170 -25.218 13.521  1.00 63.32  ? 23  A   D N1    1 
ATOM   2971 C  C2    . A   D 2 23  ? -17.849 -25.219 13.308  1.00 59.24  ? 23  A   D C2    1 
ATOM   2972 N  N3    . A   D 2 23  ? -16.880 -24.804 14.119  1.00 60.03  ? 23  A   D N3    1 
ATOM   2973 C  C4    . A   D 2 23  ? -17.380 -24.343 15.279  1.00 57.51  ? 23  A   D C4    1 
ATOM   2974 P  P     . U   D 2 24  ? -11.137 -24.522 17.869  1.00 58.12  ? 24  U   D P     1 
ATOM   2975 O  OP1   . U   D 2 24  ? -11.261 -25.995 17.753  1.00 58.32  ? 24  U   D OP1   1 
ATOM   2976 O  OP2   . U   D 2 24  ? -10.966 -23.879 19.195  1.00 59.89  ? 24  U   D OP2   1 
ATOM   2977 O  "O5'" . U   D 2 24  ? -9.892  -24.114 16.970  1.00 54.30  ? 24  U   D "O5'" 1 
ATOM   2978 C  "C5'" . U   D 2 24  ? -9.557  -22.752 16.754  1.00 60.49  ? 24  U   D "C5'" 1 
ATOM   2979 C  "C4'" . U   D 2 24  ? -8.513  -22.618 15.678  1.00 59.58  ? 24  U   D "C4'" 1 
ATOM   2980 O  "O4'" . U   D 2 24  ? -7.426  -23.542 15.949  1.00 56.12  ? 24  U   D "O4'" 1 
ATOM   2981 C  "C3'" . U   D 2 24  ? -8.995  -22.920 14.261  1.00 60.24  ? 24  U   D "C3'" 1 
ATOM   2982 O  "O3'" . U   D 2 24  ? -8.356  -22.032 13.347  1.00 64.16  ? 24  U   D "O3'" 1 
ATOM   2983 C  "C2'" . U   D 2 24  ? -8.497  -24.342 14.020  1.00 61.24  ? 24  U   D "C2'" 1 
ATOM   2984 O  "O2'" . U   D 2 24  ? -8.267  -24.646 12.662  1.00 62.97  ? 24  U   D "O2'" 1 
ATOM   2985 C  "C1'" . U   D 2 24  ? -7.197  -24.358 14.818  1.00 60.94  ? 24  U   D "C1'" 1 
ATOM   2986 N  N1    . U   D 2 24  ? -6.777  -25.685 15.303  1.00 66.33  ? 24  U   D N1    1 
ATOM   2987 C  C2    . U   D 2 24  ? -5.728  -26.339 14.674  1.00 68.47  ? 24  U   D C2    1 
ATOM   2988 O  O2    . U   D 2 24  ? -5.133  -25.887 13.713  1.00 68.72  ? 24  U   D O2    1 
ATOM   2989 N  N3    . U   D 2 24  ? -5.395  -27.557 15.216  1.00 73.14  ? 24  U   D N3    1 
ATOM   2990 C  C4    . U   D 2 24  ? -5.983  -28.179 16.301  1.00 73.88  ? 24  U   D C4    1 
ATOM   2991 O  O4    . U   D 2 24  ? -5.574  -29.283 16.669  1.00 83.33  ? 24  U   D O4    1 
ATOM   2992 C  C5    . U   D 2 24  ? -7.051  -27.444 16.899  1.00 63.65  ? 24  U   D C5    1 
ATOM   2993 C  C6    . U   D 2 24  ? -7.394  -26.255 16.393  1.00 66.04  ? 24  U   D C6    1 
ATOM   2994 P  P     . G   D 2 25  ? -8.907  -20.534 13.149  1.00 73.31  ? 25  G   D P     1 
ATOM   2995 O  OP1   . G   D 2 25  ? -8.459  -20.092 11.803  1.00 73.98  ? 25  G   D OP1   1 
ATOM   2996 O  OP2   . G   D 2 25  ? -8.592  -19.718 14.351  1.00 71.89  ? 25  G   D OP2   1 
ATOM   2997 O  "O5'" . G   D 2 25  ? -10.490 -20.696 13.129  1.00 68.33  ? 25  G   D "O5'" 1 
ATOM   2998 C  "C5'" . G   D 2 25  ? -11.167 -21.173 11.972  1.00 65.50  ? 25  G   D "C5'" 1 
ATOM   2999 C  "C4'" . G   D 2 25  ? -12.552 -20.589 11.869  1.00 62.41  ? 25  G   D "C4'" 1 
ATOM   3000 O  "O4'" . G   D 2 25  ? -13.294 -20.927 13.075  1.00 63.81  ? 25  G   D "O4'" 1 
ATOM   3001 C  "C3'" . G   D 2 25  ? -12.597 -19.065 11.749  1.00 67.71  ? 25  G   D "C3'" 1 
ATOM   3002 O  "O3'" . G   D 2 25  ? -13.666 -18.670 10.898  1.00 73.51  ? 25  G   D "O3'" 1 
ATOM   3003 C  "C2'" . G   D 2 25  ? -12.900 -18.616 13.173  1.00 67.09  ? 25  G   D "C2'" 1 
ATOM   3004 O  "O2'" . G   D 2 25  ? -13.549 -17.365 13.272  1.00 65.21  ? 25  G   D "O2'" 1 
ATOM   3005 C  "C1'" . G   D 2 25  ? -13.791 -19.747 13.672  1.00 68.26  ? 25  G   D "C1'" 1 
ATOM   3006 N  N9    . G   D 2 25  ? -13.778 -19.879 15.132  1.00 64.36  ? 25  G   D N9    1 
ATOM   3007 C  C8    . G   D 2 25  ? -12.676 -19.881 15.955  1.00 61.04  ? 25  G   D C8    1 
ATOM   3008 N  N7    . G   D 2 25  ? -12.988 -19.976 17.219  1.00 61.87  ? 25  G   D N7    1 
ATOM   3009 C  C5    . G   D 2 25  ? -14.377 -20.020 17.228  1.00 63.06  ? 25  G   D C5    1 
ATOM   3010 C  C6    . G   D 2 25  ? -15.289 -20.122 18.307  1.00 64.78  ? 25  G   D C6    1 
ATOM   3011 O  O6    . G   D 2 25  ? -15.033 -20.186 19.513  1.00 65.24  ? 25  G   D O6    1 
ATOM   3012 N  N1    . G   D 2 25  ? -16.609 -20.136 17.866  1.00 60.34  ? 25  G   D N1    1 
ATOM   3013 C  C2    . G   D 2 25  ? -16.995 -20.061 16.553  1.00 57.30  ? 25  G   D C2    1 
ATOM   3014 N  N2    . G   D 2 25  ? -18.307 -20.087 16.321  1.00 60.20  ? 25  G   D N2    1 
ATOM   3015 N  N3    . G   D 2 25  ? -16.165 -19.966 15.536  1.00 59.71  ? 25  G   D N3    1 
ATOM   3016 C  C4    . G   D 2 25  ? -14.881 -19.950 15.949  1.00 62.41  ? 25  G   D C4    1 
ATOM   3017 P  P     . A   D 2 26  ? -13.669 -17.197 10.266  1.00 77.00  ? 26  A   D P     1 
ATOM   3018 O  OP1   . A   D 2 26  ? -12.297 -16.645 10.439  1.00 72.62  ? 26  A   D OP1   1 
ATOM   3019 O  OP2   . A   D 2 26  ? -14.814 -16.436 10.850  1.00 63.71  ? 26  A   D OP2   1 
ATOM   3020 O  "O5'" . A   D 2 26  ? -13.943 -17.482 8.724   1.00 69.66  ? 26  A   D "O5'" 1 
ATOM   3021 C  "C5'" . A   D 2 26  ? -13.162 -18.435 8.017   1.00 67.74  ? 26  A   D "C5'" 1 
ATOM   3022 C  "C4'" . A   D 2 26  ? -14.024 -19.453 7.311   1.00 69.45  ? 26  A   D "C4'" 1 
ATOM   3023 O  "O4'" . A   D 2 26  ? -14.709 -20.276 8.287   1.00 66.78  ? 26  A   D "O4'" 1 
ATOM   3024 C  "C3'" . A   D 2 26  ? -15.143 -18.898 6.440   1.00 74.70  ? 26  A   D "C3'" 1 
ATOM   3025 O  "O3'" . A   D 2 26  ? -14.696 -18.506 5.155   1.00 73.82  ? 26  A   D "O3'" 1 
ATOM   3026 C  "C2'" . A   D 2 26  ? -16.142 -20.048 6.405   1.00 72.92  ? 26  A   D "C2'" 1 
ATOM   3027 O  "O2'" . A   D 2 26  ? -15.739 -21.041 5.469   1.00 60.99  ? 26  A   D "O2'" 1 
ATOM   3028 C  "C1'" . A   D 2 26  ? -15.995 -20.616 7.817   1.00 69.12  ? 26  A   D "C1'" 1 
ATOM   3029 N  N9    . A   D 2 26  ? -16.995 -20.075 8.760   1.00 62.57  ? 26  A   D N9    1 
ATOM   3030 C  C8    . A   D 2 26  ? -16.740 -19.364 9.907   1.00 64.69  ? 26  A   D C8    1 
ATOM   3031 N  N7    . A   D 2 26  ? -17.816 -19.017 10.574  1.00 64.88  ? 26  A   D N7    1 
ATOM   3032 C  C5    . A   D 2 26  ? -18.853 -19.541 9.816   1.00 63.38  ? 26  A   D C5    1 
ATOM   3033 C  C6    . A   D 2 26  ? -20.246 -19.525 9.995   1.00 63.43  ? 26  A   D C6    1 
ATOM   3034 N  N6    . A   D 2 26  ? -20.846 -18.928 11.027  1.00 68.11  ? 26  A   D N6    1 
ATOM   3035 N  N1    . A   D 2 26  ? -21.004 -20.147 9.065   1.00 60.93  ? 26  A   D N1    1 
ATOM   3036 C  C2    . A   D 2 26  ? -20.392 -20.746 8.035   1.00 61.14  ? 26  A   D C2    1 
ATOM   3037 N  N3    . A   D 2 26  ? -19.093 -20.831 7.759   1.00 59.02  ? 26  A   D N3    1 
ATOM   3038 C  C4    . A   D 2 26  ? -18.365 -20.202 8.699   1.00 60.95  ? 26  A   D C4    1 
ATOM   3039 P  P     . C   D 2 27  ? -15.085 -17.064 4.572   1.00 80.32  ? 27  C   D P     1 
ATOM   3040 O  OP1   . C   D 2 27  ? -14.603 -16.981 3.166   1.00 81.67  ? 27  C   D OP1   1 
ATOM   3041 O  OP2   . C   D 2 27  ? -14.630 -16.059 5.568   1.00 81.70  ? 27  C   D OP2   1 
ATOM   3042 O  "O5'" . C   D 2 27  ? -16.679 -17.059 4.583   1.00 74.95  ? 27  C   D "O5'" 1 
ATOM   3043 C  "C5'" . C   D 2 27  ? -17.427 -17.973 3.794   1.00 73.87  ? 27  C   D "C5'" 1 
ATOM   3044 C  "C4'" . C   D 2 27  ? -18.884 -17.965 4.186   1.00 77.40  ? 27  C   D "C4'" 1 
ATOM   3045 O  "O4'" . C   D 2 27  ? -19.036 -18.472 5.536   1.00 75.63  ? 27  C   D "O4'" 1 
ATOM   3046 C  "C3'" . C   D 2 27  ? -19.544 -16.598 4.232   1.00 84.82  ? 27  C   D "C3'" 1 
ATOM   3047 O  "O3'" . C   D 2 27  ? -19.941 -16.143 2.954   1.00 99.85  ? 27  C   D "O3'" 1 
ATOM   3048 C  "C2'" . C   D 2 27  ? -20.699 -16.807 5.207   1.00 74.95  ? 27  C   D "C2'" 1 
ATOM   3049 O  "O2'" . C   D 2 27  ? -21.805 -17.434 4.574   1.00 73.80  ? 27  C   D "O2'" 1 
ATOM   3050 C  "C1'" . C   D 2 27  ? -20.087 -17.796 6.194   1.00 67.92  ? 27  C   D "C1'" 1 
ATOM   3051 N  N1    . C   D 2 27  ? -19.536 -17.141 7.399   1.00 63.82  ? 27  C   D N1    1 
ATOM   3052 C  C2    . C   D 2 27  ? -20.420 -16.681 8.374   1.00 67.40  ? 27  C   D C2    1 
ATOM   3053 O  O2    . C   D 2 27  ? -21.642 -16.812 8.189   1.00 74.11  ? 27  C   D O2    1 
ATOM   3054 N  N3    . C   D 2 27  ? -19.919 -16.105 9.487   1.00 62.61  ? 27  C   D N3    1 
ATOM   3055 C  C4    . C   D 2 27  ? -18.600 -15.997 9.636   1.00 64.83  ? 27  C   D C4    1 
ATOM   3056 N  N4    . C   D 2 27  ? -18.147 -15.421 10.749  1.00 69.87  ? 27  C   D N4    1 
ATOM   3057 C  C5    . C   D 2 27  ? -17.675 -16.461 8.659   1.00 67.17  ? 27  C   D C5    1 
ATOM   3058 C  C6    . C   D 2 27  ? -18.186 -17.030 7.565   1.00 65.19  ? 27  C   D C6    1 
ATOM   3059 P  P     . G   D 2 28  ? -19.937 -14.572 2.647   1.00 106.96 ? 28  G   D P     1 
ATOM   3060 O  OP1   . G   D 2 28  ? -21.250 -14.243 2.031   1.00 111.38 ? 28  G   D OP1   1 
ATOM   3061 O  OP2   . G   D 2 28  ? -18.673 -14.204 1.949   1.00 95.15  ? 28  G   D OP2   1 
ATOM   3062 O  "O5'" . G   D 2 28  ? -19.921 -13.938 4.103   1.00 76.43  ? 28  G   D "O5'" 1 
ATOM   3063 C  "C5'" . G   D 2 28  ? -20.472 -12.656 4.327   1.00 85.98  ? 28  G   D "C5'" 1 
ATOM   3064 C  "C4'" . G   D 2 28  ? -21.553 -12.668 5.379   1.00 85.33  ? 28  G   D "C4'" 1 
ATOM   3065 O  "O4'" . G   D 2 28  ? -21.196 -13.561 6.464   1.00 82.73  ? 28  G   D "O4'" 1 
ATOM   3066 C  "C3'" . G   D 2 28  ? -21.766 -11.322 6.050   1.00 86.70  ? 28  G   D "C3'" 1 
ATOM   3067 O  "O3'" . G   D 2 28  ? -22.613 -10.482 5.297   1.00 90.11  ? 28  G   D "O3'" 1 
ATOM   3068 C  "C2'" . G   D 2 28  ? -22.292 -11.692 7.430   1.00 78.11  ? 28  G   D "C2'" 1 
ATOM   3069 O  "O2'" . G   D 2 28  ? -23.675 -12.008 7.381   1.00 74.95  ? 28  G   D "O2'" 1 
ATOM   3070 C  "C1'" . G   D 2 28  ? -21.511 -12.971 7.708   1.00 74.62  ? 28  G   D "C1'" 1 
ATOM   3071 N  N9    . G   D 2 28  ? -20.235 -12.708 8.391   1.00 69.41  ? 28  G   D N9    1 
ATOM   3072 C  C8    . G   D 2 28  ? -19.026 -13.131 7.893   1.00 69.33  ? 28  G   D C8    1 
ATOM   3073 N  N7    . G   D 2 28  ? -18.013 -12.807 8.638   1.00 68.78  ? 28  G   D N7    1 
ATOM   3074 C  C5    . G   D 2 28  ? -18.595 -12.134 9.700   1.00 68.46  ? 28  G   D C5    1 
ATOM   3075 C  C6    . G   D 2 28  ? -17.967 -11.558 10.826  1.00 68.27  ? 28  G   D C6    1 
ATOM   3076 O  O6    . G   D 2 28  ? -16.755 -11.550 11.066  1.00 65.30  ? 28  G   D O6    1 
ATOM   3077 N  N1    . G   D 2 28  ? -18.885 -10.959 11.687  1.00 68.50  ? 28  G   D N1    1 
ATOM   3078 C  C2    . G   D 2 28  ? -20.247 -10.920 11.486  1.00 66.45  ? 28  G   D C2    1 
ATOM   3079 N  N2    . G   D 2 28  ? -20.963 -10.293 12.435  1.00 56.35  ? 28  G   D N2    1 
ATOM   3080 N  N3    . G   D 2 28  ? -20.851 -11.466 10.427  1.00 67.78  ? 28  G   D N3    1 
ATOM   3081 C  C4    . G   D 2 28  ? -19.970 -12.055 9.577   1.00 70.03  ? 28  G   D C4    1 
ATOM   3082 P  P     . C   D 2 29  ? -21.974 -9.291  4.437   1.00 93.47  ? 29  C   D P     1 
ATOM   3083 O  OP1   . C   D 2 29  ? -22.743 -9.178  3.167   1.00 86.57  ? 29  C   D OP1   1 
ATOM   3084 O  OP2   . C   D 2 29  ? -20.497 -9.488  4.382   1.00 78.67  ? 29  C   D OP2   1 
ATOM   3085 O  "O5'" . C   D 2 29  ? -22.269 -8.027  5.352   1.00 87.26  ? 29  C   D "O5'" 1 
ATOM   3086 C  "C5'" . C   D 2 29  ? -23.455 -7.979  6.130   1.00 83.97  ? 29  C   D "C5'" 1 
ATOM   3087 C  "C4'" . C   D 2 29  ? -23.239 -7.258  7.436   1.00 83.31  ? 29  C   D "C4'" 1 
ATOM   3088 O  "O4'" . C   D 2 29  ? -22.628 -8.145  8.410   1.00 81.51  ? 29  C   D "O4'" 1 
ATOM   3089 C  "C3'" . C   D 2 29  ? -22.299 -6.067  7.392   1.00 86.03  ? 29  C   D "C3'" 1 
ATOM   3090 O  "O3'" . C   D 2 29  ? -22.896 -4.905  6.841   1.00 92.57  ? 29  C   D "O3'" 1 
ATOM   3091 C  "C2'" . C   D 2 29  ? -21.883 -5.931  8.852   1.00 86.91  ? 29  C   D "C2'" 1 
ATOM   3092 O  "O2'" . C   D 2 29  ? -22.909 -5.314  9.616   1.00 78.53  ? 29  C   D "O2'" 1 
ATOM   3093 C  "C1'" . C   D 2 29  ? -21.784 -7.402  9.268   1.00 78.35  ? 29  C   D "C1'" 1 
ATOM   3094 N  N1    . C   D 2 29  ? -20.401 -7.910  9.137   1.00 67.47  ? 29  C   D N1    1 
ATOM   3095 C  C2    . C   D 2 29  ? -19.512 -7.638  10.179  1.00 73.17  ? 29  C   D C2    1 
ATOM   3096 O  O2    . C   D 2 29  ? -19.932 -7.002  11.158  1.00 71.60  ? 29  C   D O2    1 
ATOM   3097 N  N3    . C   D 2 29  ? -18.234 -8.073  10.097  1.00 79.33  ? 29  C   D N3    1 
ATOM   3098 C  C4    . C   D 2 29  ? -17.836 -8.754  9.020   1.00 79.90  ? 29  C   D C4    1 
ATOM   3099 N  N4    . C   D 2 29  ? -16.566 -9.172  8.978   1.00 85.92  ? 29  C   D N4    1 
ATOM   3100 C  C5    . C   D 2 29  ? -18.723 -9.040  7.939   1.00 75.78  ? 29  C   D C5    1 
ATOM   3101 C  C6    . C   D 2 29  ? -19.985 -8.605  8.035   1.00 69.21  ? 29  C   D C6    1 
ATOM   3102 P  P     . A   D 2 30  ? -22.053 -3.924  5.883   1.00 92.50  ? 30  A   D P     1 
ATOM   3103 O  OP1   . A   D 2 30  ? -22.859 -3.584  4.678   1.00 82.03  ? 30  A   D OP1   1 
ATOM   3104 O  OP2   . A   D 2 30  ? -20.691 -4.490  5.704   1.00 84.95  ? 30  A   D OP2   1 
ATOM   3105 O  "O5'" . A   D 2 30  ? -21.947 -2.597  6.750   1.00 96.44  ? 30  A   D "O5'" 1 
ATOM   3106 C  "C5'" . A   D 2 30  ? -20.736 -1.871  6.814   1.00 94.74  ? 30  A   D "C5'" 1 
ATOM   3107 C  "C4'" . A   D 2 30  ? -20.295 -1.668  8.237   1.00 91.04  ? 30  A   D "C4'" 1 
ATOM   3108 O  "O4'" . A   D 2 30  ? -20.114 -2.949  8.891   1.00 85.55  ? 30  A   D "O4'" 1 
ATOM   3109 C  "C3'" . A   D 2 30  ? -18.953 -0.983  8.387   1.00 100.91 ? 30  A   D "C3'" 1 
ATOM   3110 O  "O3'" . A   D 2 30  ? -19.056 0.421   8.262   1.00 102.51 ? 30  A   D "O3'" 1 
ATOM   3111 C  "C2'" . A   D 2 30  ? -18.480 -1.456  9.756   1.00 101.03 ? 30  A   D "C2'" 1 
ATOM   3112 O  "O2'" . A   D 2 30  ? -19.118 -0.720  10.789  1.00 100.57 ? 30  A   D "O2'" 1 
ATOM   3113 C  "C1'" . A   D 2 30  ? -19.022 -2.884  9.784   1.00 89.74  ? 30  A   D "C1'" 1 
ATOM   3114 N  N9    . A   D 2 30  ? -18.032 -3.914  9.394   1.00 87.17  ? 30  A   D N9    1 
ATOM   3115 C  C8    . A   D 2 30  ? -18.232 -4.865  8.424   1.00 88.55  ? 30  A   D C8    1 
ATOM   3116 N  N7    . A   D 2 30  ? -17.240 -5.703  8.260   1.00 89.83  ? 30  A   D N7    1 
ATOM   3117 C  C5    . A   D 2 30  ? -16.310 -5.291  9.203   1.00 94.64  ? 30  A   D C5    1 
ATOM   3118 C  C6    . A   D 2 30  ? -15.029 -5.785  9.528   1.00 97.21  ? 30  A   D C6    1 
ATOM   3119 N  N6    . A   D 2 30  ? -14.475 -6.832  8.911   1.00 97.77  ? 30  A   D N6    1 
ATOM   3120 N  N1    . A   D 2 30  ? -14.331 -5.169  10.508  1.00 94.15  ? 30  A   D N1    1 
ATOM   3121 C  C2    . A   D 2 30  ? -14.907 -4.119  11.116  1.00 97.56  ? 30  A   D C2    1 
ATOM   3122 N  N3    . A   D 2 30  ? -16.107 -3.563  10.899  1.00 96.33  ? 30  A   D N3    1 
ATOM   3123 C  C4    . A   D 2 30  ? -16.780 -4.197  9.918   1.00 92.33  ? 30  A   D C4    1 
ATOM   3124 P  P     . U   D 2 31  ? -18.506 1.159   6.947   1.00 108.35 ? 31  U   D P     1 
ATOM   3125 O  OP1   . U   D 2 31  ? -19.524 2.171   6.568   1.00 115.78 ? 31  U   D OP1   1 
ATOM   3126 O  OP2   . U   D 2 31  ? -18.068 0.165   5.934   1.00 97.69  ? 31  U   D OP2   1 
ATOM   3127 O  "O5'" . U   D 2 31  ? -17.208 1.901   7.481   1.00 109.72 ? 31  U   D "O5'" 1 
ATOM   3128 C  "C5'" . U   D 2 31  ? -17.082 2.218   8.859   1.00 110.28 ? 31  U   D "C5'" 1 
ATOM   3129 C  "C4'" . U   D 2 31  ? -15.702 1.892   9.362   1.00 116.39 ? 31  U   D "C4'" 1 
ATOM   3130 O  "O4'" . U   D 2 31  ? -15.644 0.503   9.776   1.00 115.29 ? 31  U   D "O4'" 1 
ATOM   3131 C  "C3'" . U   D 2 31  ? -14.591 2.015   8.333   1.00 127.10 ? 31  U   D "C3'" 1 
ATOM   3132 O  "O3'" . U   D 2 31  ? -14.154 3.349   8.147   1.00 137.36 ? 31  U   D "O3'" 1 
ATOM   3133 C  "C2'" . U   D 2 31  ? -13.520 1.084   8.884   1.00 127.20 ? 31  U   D "C2'" 1 
ATOM   3134 O  "O2'" . U   D 2 31  ? -12.806 1.707   9.942   1.00 130.48 ? 31  U   D "O2'" 1 
ATOM   3135 C  "C1'" . U   D 2 31  ? -14.373 -0.036  9.476   1.00 117.19 ? 31  U   D "C1'" 1 
ATOM   3136 N  N1    . U   D 2 31  ? -14.551 -1.190  8.561   1.00 110.50 ? 31  U   D N1    1 
ATOM   3137 C  C2    . U   D 2 31  ? -13.598 -2.185  8.594   1.00 109.35 ? 31  U   D C2    1 
ATOM   3138 O  O2    . U   D 2 31  ? -12.622 -2.123  9.318   1.00 111.74 ? 31  U   D O2    1 
ATOM   3139 N  N3    . U   D 2 31  ? -13.828 -3.244  7.747   1.00 109.27 ? 31  U   D N3    1 
ATOM   3140 C  C4    . U   D 2 31  ? -14.896 -3.415  6.888   1.00 104.37 ? 31  U   D C4    1 
ATOM   3141 O  O4    . U   D 2 31  ? -14.966 -4.427  6.186   1.00 102.30 ? 31  U   D O4    1 
ATOM   3142 C  C5    . U   D 2 31  ? -15.844 -2.347  6.918   1.00 104.18 ? 31  U   D C5    1 
ATOM   3143 C  C6    . U   D 2 31  ? -15.640 -1.303  7.729   1.00 107.17 ? 31  U   D C6    1 
ATOM   3144 P  P     . C   D 2 32  ? -13.724 3.858   6.685   1.00 139.71 ? 32  C   D P     1 
ATOM   3145 O  OP1   . C   D 2 32  ? -14.215 5.250   6.513   1.00 130.35 ? 32  C   D OP1   1 
ATOM   3146 O  OP2   . C   D 2 32  ? -14.154 2.829   5.702   1.00 130.28 ? 32  C   D OP2   1 
ATOM   3147 O  "O5'" . C   D 2 32  ? -12.128 3.833   6.726   1.00 144.85 ? 32  C   D "O5'" 1 
ATOM   3148 C  "C5'" . C   D 2 32  ? -11.414 4.085   7.931   1.00 142.65 ? 32  C   D "C5'" 1 
ATOM   3149 C  "C4'" . C   D 2 32  ? -10.120 3.303   7.999   1.00 143.12 ? 32  C   D "C4'" 1 
ATOM   3150 O  "O4'" . C   D 2 32  ? -10.385 1.925   8.373   1.00 142.66 ? 32  C   D "O4'" 1 
ATOM   3151 C  "C3'" . C   D 2 32  ? -9.333  3.188   6.701   1.00 145.65 ? 32  C   D "C3'" 1 
ATOM   3152 O  "O3'" . C   D 2 32  ? -8.563  4.343   6.409   1.00 135.18 ? 32  C   D "O3'" 1 
ATOM   3153 C  "C2'" . C   D 2 32  ? -8.494  1.934   6.924   1.00 145.31 ? 32  C   D "C2'" 1 
ATOM   3154 O  "O2'" . C   D 2 32  ? -7.347  2.225   7.709   1.00 149.67 ? 32  C   D "O2'" 1 
ATOM   3155 C  "C1'" . C   D 2 32  ? -9.448  1.067   7.753   1.00 140.27 ? 32  C   D "C1'" 1 
ATOM   3156 N  N1    . C   D 2 32  ? -10.166 0.073   6.920   1.00 133.81 ? 32  C   D N1    1 
ATOM   3157 C  C2    . C   D 2 32  ? -9.562  -1.171  6.725   1.00 137.10 ? 32  C   D C2    1 
ATOM   3158 O  O2    . C   D 2 32  ? -8.467  -1.397  7.255   1.00 141.72 ? 32  C   D O2    1 
ATOM   3159 N  N3    . C   D 2 32  ? -10.172 -2.109  5.964   1.00 136.27 ? 32  C   D N3    1 
ATOM   3160 C  C4    . C   D 2 32  ? -11.351 -1.843  5.401   1.00 133.44 ? 32  C   D C4    1 
ATOM   3161 N  N4    . C   D 2 32  ? -11.921 -2.799  4.659   1.00 131.02 ? 32  C   D N4    1 
ATOM   3162 C  C5    . C   D 2 32  ? -11.995 -0.582  5.578   1.00 127.15 ? 32  C   D C5    1 
ATOM   3163 C  C6    . C   D 2 32  ? -11.373 0.337   6.331   1.00 129.32 ? 32  C   D C6    1 
HETATM 3164 CA CA    . CA  E 3 .   ? 26.642  -13.542 5.467   1.00 75.36  ? 101 CA  B CA    1 
HETATM 3165 CA CA    . CA  F 3 .   ? 28.906  -16.006 -4.618  1.00 101.61 ? 102 CA  B CA    1 
HETATM 3166 CA CA    . CA  G 3 .   ? -25.850 -25.853 4.075   1.00 95.27  ? 101 CA  D CA    1 
HETATM 3167 CA CA    . CA  H 3 .   ? -24.896 -34.996 -1.152  1.00 75.43  ? 102 CA  D CA    1 
HETATM 3168 CA CA    . CA  I 3 .   ? -15.052 6.949   3.439   1.00 107.49 ? 103 CA  D CA    1 
# 
