data_9L4A
# 
_entry.id   9L4A 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9L4A         pdb_00009l4a 10.2210/pdb9l4a/pdb 
WWPDB D_1300054909 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-03-19 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9L4A 
_pdbx_database_status.recvd_initial_deposition_date   2024-12-20 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              weipengcheng@gxu.edu.cn 
_pdbx_contact_author.name_first         pengcheng 
_pdbx_contact_author.name_last          Wei 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-0002-9439 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Yang, M.'    1 0000-0003-4792-9493 
'Zhong, P.L.' 2 0009-0002-2682-895X 
'Wei, P.C.'   3 0000-0003-0002-9439 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Int.J.Biol.Macromol. 
_citation.journal_id_ASTM           IJBMDR 
_citation.journal_id_CSD            0708 
_citation.journal_id_ISSN           0141-8130 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            306 
_citation.language                  ? 
_citation.page_first                141681 
_citation.page_last                 141681 
_citation.title                     
;Biochemical and structural insights into position 97 micropolymorphisms in human leukocyte antigen (HLA)-C*12 allotypes and their differential disease associations.
;
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.ijbiomac.2025.141681 
_citation.pdbx_database_id_PubMed   40044006 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Yang, M.'  1 ? 
primary 'Zhong, P.' 2 ? 
primary 'Liu, Q.'   3 ? 
primary 'Jiao, H.'  4 ? 
primary 'Lei, J.'   5 ? 
primary 'Wei, P.'   6 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'MHC class I antigen' 31674.764 2    ? ? ? ? 
2 polymer man Beta-2-microglobulin  11676.032 2    ? ? ? ? 
3 polymer man MY9                   1147.303  2    ? ? ? ? 
4 water   nat water                 18.015    1009 ? ? ? ? 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;SHSMRYFYTAVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRGEPRAPWVEQEGPEYWDRETQKYKRQAQADRVSLRNL
RGYYNQSEAGSHTLQRMYGCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREAEQWRAYLE
GTCVEWLRRYLENGKETLQRAEHPKTHVTHHPVSDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTF
QKWAAVVVPSGEEQRYTCHVQHEGLPEPLTLRW
;
;SHSMRYFYTAVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRGEPRAPWVEQEGPEYWDRETQKYKRQAQADRVSLRNL
RGYYNQSEAGSHTLQRMYGCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREAEQWRAYLE
GTCVEWLRRYLENGKETLQRAEHPKTHVTHHPVSDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTF
QKWAAVVVPSGEEQRYTCHVQHEGLPEPLTLRW
;
A,D ? 
2 'polypeptide(L)' no no 
;IQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLLKNGERIEKVEHSDLSFSGDWSFYLLYYTEFTPTEKDEYAC
RVNHVTLSQPKIVKWDRDM
;
;IQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLLKNGERIEKVEHSDLSFSGDWSFYLLYYTEFTPTEKDEYAC
RVNHVTLSQPKIVKWDRDM
;
B,E ? 
3 'polypeptide(L)' no no MARELHPEY MARELHPEY C,F ? 
# 
_pdbx_entity_nonpoly.entity_id   4 
_pdbx_entity_nonpoly.name        water 
_pdbx_entity_nonpoly.comp_id     HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   SER n 
1 2   HIS n 
1 3   SER n 
1 4   MET n 
1 5   ARG n 
1 6   TYR n 
1 7   PHE n 
1 8   TYR n 
1 9   THR n 
1 10  ALA n 
1 11  VAL n 
1 12  SER n 
1 13  ARG n 
1 14  PRO n 
1 15  GLY n 
1 16  ARG n 
1 17  GLY n 
1 18  GLU n 
1 19  PRO n 
1 20  ARG n 
1 21  PHE n 
1 22  ILE n 
1 23  ALA n 
1 24  VAL n 
1 25  GLY n 
1 26  TYR n 
1 27  VAL n 
1 28  ASP n 
1 29  ASP n 
1 30  THR n 
1 31  GLN n 
1 32  PHE n 
1 33  VAL n 
1 34  ARG n 
1 35  PHE n 
1 36  ASP n 
1 37  SER n 
1 38  ASP n 
1 39  ALA n 
1 40  ALA n 
1 41  SER n 
1 42  PRO n 
1 43  ARG n 
1 44  GLY n 
1 45  GLU n 
1 46  PRO n 
1 47  ARG n 
1 48  ALA n 
1 49  PRO n 
1 50  TRP n 
1 51  VAL n 
1 52  GLU n 
1 53  GLN n 
1 54  GLU n 
1 55  GLY n 
1 56  PRO n 
1 57  GLU n 
1 58  TYR n 
1 59  TRP n 
1 60  ASP n 
1 61  ARG n 
1 62  GLU n 
1 63  THR n 
1 64  GLN n 
1 65  LYS n 
1 66  TYR n 
1 67  LYS n 
1 68  ARG n 
1 69  GLN n 
1 70  ALA n 
1 71  GLN n 
1 72  ALA n 
1 73  ASP n 
1 74  ARG n 
1 75  VAL n 
1 76  SER n 
1 77  LEU n 
1 78  ARG n 
1 79  ASN n 
1 80  LEU n 
1 81  ARG n 
1 82  GLY n 
1 83  TYR n 
1 84  TYR n 
1 85  ASN n 
1 86  GLN n 
1 87  SER n 
1 88  GLU n 
1 89  ALA n 
1 90  GLY n 
1 91  SER n 
1 92  HIS n 
1 93  THR n 
1 94  LEU n 
1 95  GLN n 
1 96  ARG n 
1 97  MET n 
1 98  TYR n 
1 99  GLY n 
1 100 CYS n 
1 101 ASP n 
1 102 LEU n 
1 103 GLY n 
1 104 PRO n 
1 105 ASP n 
1 106 GLY n 
1 107 ARG n 
1 108 LEU n 
1 109 LEU n 
1 110 ARG n 
1 111 GLY n 
1 112 TYR n 
1 113 ASP n 
1 114 GLN n 
1 115 SER n 
1 116 ALA n 
1 117 TYR n 
1 118 ASP n 
1 119 GLY n 
1 120 LYS n 
1 121 ASP n 
1 122 TYR n 
1 123 ILE n 
1 124 ALA n 
1 125 LEU n 
1 126 ASN n 
1 127 GLU n 
1 128 ASP n 
1 129 LEU n 
1 130 ARG n 
1 131 SER n 
1 132 TRP n 
1 133 THR n 
1 134 ALA n 
1 135 ALA n 
1 136 ASP n 
1 137 THR n 
1 138 ALA n 
1 139 ALA n 
1 140 GLN n 
1 141 ILE n 
1 142 THR n 
1 143 GLN n 
1 144 ARG n 
1 145 LYS n 
1 146 TRP n 
1 147 GLU n 
1 148 ALA n 
1 149 ALA n 
1 150 ARG n 
1 151 GLU n 
1 152 ALA n 
1 153 GLU n 
1 154 GLN n 
1 155 TRP n 
1 156 ARG n 
1 157 ALA n 
1 158 TYR n 
1 159 LEU n 
1 160 GLU n 
1 161 GLY n 
1 162 THR n 
1 163 CYS n 
1 164 VAL n 
1 165 GLU n 
1 166 TRP n 
1 167 LEU n 
1 168 ARG n 
1 169 ARG n 
1 170 TYR n 
1 171 LEU n 
1 172 GLU n 
1 173 ASN n 
1 174 GLY n 
1 175 LYS n 
1 176 GLU n 
1 177 THR n 
1 178 LEU n 
1 179 GLN n 
1 180 ARG n 
1 181 ALA n 
1 182 GLU n 
1 183 HIS n 
1 184 PRO n 
1 185 LYS n 
1 186 THR n 
1 187 HIS n 
1 188 VAL n 
1 189 THR n 
1 190 HIS n 
1 191 HIS n 
1 192 PRO n 
1 193 VAL n 
1 194 SER n 
1 195 ASP n 
1 196 HIS n 
1 197 GLU n 
1 198 ALA n 
1 199 THR n 
1 200 LEU n 
1 201 ARG n 
1 202 CYS n 
1 203 TRP n 
1 204 ALA n 
1 205 LEU n 
1 206 GLY n 
1 207 PHE n 
1 208 TYR n 
1 209 PRO n 
1 210 ALA n 
1 211 GLU n 
1 212 ILE n 
1 213 THR n 
1 214 LEU n 
1 215 THR n 
1 216 TRP n 
1 217 GLN n 
1 218 ARG n 
1 219 ASP n 
1 220 GLY n 
1 221 GLU n 
1 222 ASP n 
1 223 GLN n 
1 224 THR n 
1 225 GLN n 
1 226 ASP n 
1 227 THR n 
1 228 GLU n 
1 229 LEU n 
1 230 VAL n 
1 231 GLU n 
1 232 THR n 
1 233 ARG n 
1 234 PRO n 
1 235 ALA n 
1 236 GLY n 
1 237 ASP n 
1 238 GLY n 
1 239 THR n 
1 240 PHE n 
1 241 GLN n 
1 242 LYS n 
1 243 TRP n 
1 244 ALA n 
1 245 ALA n 
1 246 VAL n 
1 247 VAL n 
1 248 VAL n 
1 249 PRO n 
1 250 SER n 
1 251 GLY n 
1 252 GLU n 
1 253 GLU n 
1 254 GLN n 
1 255 ARG n 
1 256 TYR n 
1 257 THR n 
1 258 CYS n 
1 259 HIS n 
1 260 VAL n 
1 261 GLN n 
1 262 HIS n 
1 263 GLU n 
1 264 GLY n 
1 265 LEU n 
1 266 PRO n 
1 267 GLU n 
1 268 PRO n 
1 269 LEU n 
1 270 THR n 
1 271 LEU n 
1 272 ARG n 
1 273 TRP n 
2 1   ILE n 
2 2   GLN n 
2 3   ARG n 
2 4   THR n 
2 5   PRO n 
2 6   LYS n 
2 7   ILE n 
2 8   GLN n 
2 9   VAL n 
2 10  TYR n 
2 11  SER n 
2 12  ARG n 
2 13  HIS n 
2 14  PRO n 
2 15  ALA n 
2 16  GLU n 
2 17  ASN n 
2 18  GLY n 
2 19  LYS n 
2 20  SER n 
2 21  ASN n 
2 22  PHE n 
2 23  LEU n 
2 24  ASN n 
2 25  CYS n 
2 26  TYR n 
2 27  VAL n 
2 28  SER n 
2 29  GLY n 
2 30  PHE n 
2 31  HIS n 
2 32  PRO n 
2 33  SER n 
2 34  ASP n 
2 35  ILE n 
2 36  GLU n 
2 37  VAL n 
2 38  ASP n 
2 39  LEU n 
2 40  LEU n 
2 41  LYS n 
2 42  ASN n 
2 43  GLY n 
2 44  GLU n 
2 45  ARG n 
2 46  ILE n 
2 47  GLU n 
2 48  LYS n 
2 49  VAL n 
2 50  GLU n 
2 51  HIS n 
2 52  SER n 
2 53  ASP n 
2 54  LEU n 
2 55  SER n 
2 56  PHE n 
2 57  SER n 
2 58  GLY n 
2 59  ASP n 
2 60  TRP n 
2 61  SER n 
2 62  PHE n 
2 63  TYR n 
2 64  LEU n 
2 65  LEU n 
2 66  TYR n 
2 67  TYR n 
2 68  THR n 
2 69  GLU n 
2 70  PHE n 
2 71  THR n 
2 72  PRO n 
2 73  THR n 
2 74  GLU n 
2 75  LYS n 
2 76  ASP n 
2 77  GLU n 
2 78  TYR n 
2 79  ALA n 
2 80  CYS n 
2 81  ARG n 
2 82  VAL n 
2 83  ASN n 
2 84  HIS n 
2 85  VAL n 
2 86  THR n 
2 87  LEU n 
2 88  SER n 
2 89  GLN n 
2 90  PRO n 
2 91  LYS n 
2 92  ILE n 
2 93  VAL n 
2 94  LYS n 
2 95  TRP n 
2 96  ASP n 
2 97  ARG n 
2 98  ASP n 
2 99  MET n 
3 1   MET n 
3 2   ALA n 
3 3   ARG n 
3 4   GLU n 
3 5   LEU n 
3 6   HIS n 
3 7   PRO n 
3 8   GLU n 
3 9   TYR n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 273 human ? HLA-C                      ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Escherichia coli' 562 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 99  human ? 'B2M, CDABP0092, HDCMA22P' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Escherichia coli' 562 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 9   human ? ?                          ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Escherichia coli' 562 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER           ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   SER 1   2   2   SER SER A . n 
A 1 2   HIS 2   3   3   HIS HIS A . n 
A 1 3   SER 3   4   4   SER SER A . n 
A 1 4   MET 4   5   5   MET MET A . n 
A 1 5   ARG 5   6   6   ARG ARG A . n 
A 1 6   TYR 6   7   7   TYR TYR A . n 
A 1 7   PHE 7   8   8   PHE PHE A . n 
A 1 8   TYR 8   9   9   TYR TYR A . n 
A 1 9   THR 9   10  10  THR THR A . n 
A 1 10  ALA 10  11  11  ALA ALA A . n 
A 1 11  VAL 11  12  12  VAL VAL A . n 
A 1 12  SER 12  13  13  SER SER A . n 
A 1 13  ARG 13  14  14  ARG ARG A . n 
A 1 14  PRO 14  15  15  PRO PRO A . n 
A 1 15  GLY 15  16  16  GLY GLY A . n 
A 1 16  ARG 16  17  17  ARG ARG A . n 
A 1 17  GLY 17  18  18  GLY GLY A . n 
A 1 18  GLU 18  19  19  GLU GLU A . n 
A 1 19  PRO 19  20  20  PRO PRO A . n 
A 1 20  ARG 20  21  21  ARG ARG A . n 
A 1 21  PHE 21  22  22  PHE PHE A . n 
A 1 22  ILE 22  23  23  ILE ILE A . n 
A 1 23  ALA 23  24  24  ALA ALA A . n 
A 1 24  VAL 24  25  25  VAL VAL A . n 
A 1 25  GLY 25  26  26  GLY GLY A . n 
A 1 26  TYR 26  27  27  TYR TYR A . n 
A 1 27  VAL 27  28  28  VAL VAL A . n 
A 1 28  ASP 28  29  29  ASP ASP A . n 
A 1 29  ASP 29  30  30  ASP ASP A . n 
A 1 30  THR 30  31  31  THR THR A . n 
A 1 31  GLN 31  32  32  GLN GLN A . n 
A 1 32  PHE 32  33  33  PHE PHE A . n 
A 1 33  VAL 33  34  34  VAL VAL A . n 
A 1 34  ARG 34  35  35  ARG ARG A . n 
A 1 35  PHE 35  36  36  PHE PHE A . n 
A 1 36  ASP 36  37  37  ASP ASP A . n 
A 1 37  SER 37  38  38  SER SER A . n 
A 1 38  ASP 38  39  39  ASP ASP A . n 
A 1 39  ALA 39  40  40  ALA ALA A . n 
A 1 40  ALA 40  41  41  ALA ALA A . n 
A 1 41  SER 41  42  42  SER SER A . n 
A 1 42  PRO 42  43  43  PRO PRO A . n 
A 1 43  ARG 43  44  44  ARG ARG A . n 
A 1 44  GLY 44  45  45  GLY GLY A . n 
A 1 45  GLU 45  46  46  GLU GLU A . n 
A 1 46  PRO 46  47  47  PRO PRO A . n 
A 1 47  ARG 47  48  48  ARG ARG A . n 
A 1 48  ALA 48  49  49  ALA ALA A . n 
A 1 49  PRO 49  50  50  PRO PRO A . n 
A 1 50  TRP 50  51  51  TRP TRP A . n 
A 1 51  VAL 51  52  52  VAL VAL A . n 
A 1 52  GLU 52  53  53  GLU GLU A . n 
A 1 53  GLN 53  54  54  GLN GLN A . n 
A 1 54  GLU 54  55  55  GLU GLU A . n 
A 1 55  GLY 55  56  56  GLY GLY A . n 
A 1 56  PRO 56  57  57  PRO PRO A . n 
A 1 57  GLU 57  58  58  GLU GLU A . n 
A 1 58  TYR 58  59  59  TYR TYR A . n 
A 1 59  TRP 59  60  60  TRP TRP A . n 
A 1 60  ASP 60  61  61  ASP ASP A . n 
A 1 61  ARG 61  62  62  ARG ARG A . n 
A 1 62  GLU 62  63  63  GLU GLU A . n 
A 1 63  THR 63  64  64  THR THR A . n 
A 1 64  GLN 64  65  65  GLN GLN A . n 
A 1 65  LYS 65  66  66  LYS LYS A . n 
A 1 66  TYR 66  67  67  TYR TYR A . n 
A 1 67  LYS 67  68  68  LYS LYS A . n 
A 1 68  ARG 68  69  69  ARG ARG A . n 
A 1 69  GLN 69  70  70  GLN GLN A . n 
A 1 70  ALA 70  71  71  ALA ALA A . n 
A 1 71  GLN 71  72  72  GLN GLN A . n 
A 1 72  ALA 72  73  73  ALA ALA A . n 
A 1 73  ASP 73  74  74  ASP ASP A . n 
A 1 74  ARG 74  75  75  ARG ARG A . n 
A 1 75  VAL 75  76  76  VAL VAL A . n 
A 1 76  SER 76  77  77  SER SER A . n 
A 1 77  LEU 77  78  78  LEU LEU A . n 
A 1 78  ARG 78  79  79  ARG ARG A . n 
A 1 79  ASN 79  80  80  ASN ASN A . n 
A 1 80  LEU 80  81  81  LEU LEU A . n 
A 1 81  ARG 81  82  82  ARG ARG A . n 
A 1 82  GLY 82  83  83  GLY GLY A . n 
A 1 83  TYR 83  84  84  TYR TYR A . n 
A 1 84  TYR 84  85  85  TYR TYR A . n 
A 1 85  ASN 85  86  86  ASN ASN A . n 
A 1 86  GLN 86  87  87  GLN GLN A . n 
A 1 87  SER 87  88  88  SER SER A . n 
A 1 88  GLU 88  89  89  GLU GLU A . n 
A 1 89  ALA 89  90  90  ALA ALA A . n 
A 1 90  GLY 90  91  91  GLY GLY A . n 
A 1 91  SER 91  92  92  SER SER A . n 
A 1 92  HIS 92  93  93  HIS HIS A . n 
A 1 93  THR 93  94  94  THR THR A . n 
A 1 94  LEU 94  95  95  LEU LEU A . n 
A 1 95  GLN 95  96  96  GLN GLN A . n 
A 1 96  ARG 96  97  97  ARG ARG A . n 
A 1 97  MET 97  98  98  MET MET A . n 
A 1 98  TYR 98  99  99  TYR TYR A . n 
A 1 99  GLY 99  100 100 GLY GLY A . n 
A 1 100 CYS 100 101 101 CYS CYS A . n 
A 1 101 ASP 101 102 102 ASP ASP A . n 
A 1 102 LEU 102 103 103 LEU LEU A . n 
A 1 103 GLY 103 104 104 GLY GLY A . n 
A 1 104 PRO 104 105 105 PRO PRO A . n 
A 1 105 ASP 105 106 106 ASP ASP A . n 
A 1 106 GLY 106 107 107 GLY GLY A . n 
A 1 107 ARG 107 108 108 ARG ARG A . n 
A 1 108 LEU 108 109 109 LEU LEU A . n 
A 1 109 LEU 109 110 110 LEU LEU A . n 
A 1 110 ARG 110 111 111 ARG ARG A . n 
A 1 111 GLY 111 112 112 GLY GLY A . n 
A 1 112 TYR 112 113 113 TYR TYR A . n 
A 1 113 ASP 113 114 114 ASP ASP A . n 
A 1 114 GLN 114 115 115 GLN GLN A . n 
A 1 115 SER 115 116 116 SER SER A . n 
A 1 116 ALA 116 117 117 ALA ALA A . n 
A 1 117 TYR 117 118 118 TYR TYR A . n 
A 1 118 ASP 118 119 119 ASP ASP A . n 
A 1 119 GLY 119 120 120 GLY GLY A . n 
A 1 120 LYS 120 121 121 LYS LYS A . n 
A 1 121 ASP 121 122 122 ASP ASP A . n 
A 1 122 TYR 122 123 123 TYR TYR A . n 
A 1 123 ILE 123 124 124 ILE ILE A . n 
A 1 124 ALA 124 125 125 ALA ALA A . n 
A 1 125 LEU 125 126 126 LEU LEU A . n 
A 1 126 ASN 126 127 127 ASN ASN A . n 
A 1 127 GLU 127 128 128 GLU GLU A . n 
A 1 128 ASP 128 129 129 ASP ASP A . n 
A 1 129 LEU 129 130 130 LEU LEU A . n 
A 1 130 ARG 130 131 131 ARG ARG A . n 
A 1 131 SER 131 132 132 SER SER A . n 
A 1 132 TRP 132 133 133 TRP TRP A . n 
A 1 133 THR 133 134 134 THR THR A . n 
A 1 134 ALA 134 135 135 ALA ALA A . n 
A 1 135 ALA 135 136 136 ALA ALA A . n 
A 1 136 ASP 136 137 137 ASP ASP A . n 
A 1 137 THR 137 138 138 THR THR A . n 
A 1 138 ALA 138 139 139 ALA ALA A . n 
A 1 139 ALA 139 140 140 ALA ALA A . n 
A 1 140 GLN 140 141 141 GLN GLN A . n 
A 1 141 ILE 141 142 142 ILE ILE A . n 
A 1 142 THR 142 143 143 THR THR A . n 
A 1 143 GLN 143 144 144 GLN GLN A . n 
A 1 144 ARG 144 145 145 ARG ARG A . n 
A 1 145 LYS 145 146 146 LYS LYS A . n 
A 1 146 TRP 146 147 147 TRP TRP A . n 
A 1 147 GLU 147 148 148 GLU GLU A . n 
A 1 148 ALA 148 149 149 ALA ALA A . n 
A 1 149 ALA 149 150 150 ALA ALA A . n 
A 1 150 ARG 150 151 151 ARG ARG A . n 
A 1 151 GLU 151 152 152 GLU GLU A . n 
A 1 152 ALA 152 153 153 ALA ALA A . n 
A 1 153 GLU 153 154 154 GLU GLU A . n 
A 1 154 GLN 154 155 155 GLN GLN A . n 
A 1 155 TRP 155 156 156 TRP TRP A . n 
A 1 156 ARG 156 157 157 ARG ARG A . n 
A 1 157 ALA 157 158 158 ALA ALA A . n 
A 1 158 TYR 158 159 159 TYR TYR A . n 
A 1 159 LEU 159 160 160 LEU LEU A . n 
A 1 160 GLU 160 161 161 GLU GLU A . n 
A 1 161 GLY 161 162 162 GLY GLY A . n 
A 1 162 THR 162 163 163 THR THR A . n 
A 1 163 CYS 163 164 164 CYS CYS A . n 
A 1 164 VAL 164 165 165 VAL VAL A . n 
A 1 165 GLU 165 166 166 GLU GLU A . n 
A 1 166 TRP 166 167 167 TRP TRP A . n 
A 1 167 LEU 167 168 168 LEU LEU A . n 
A 1 168 ARG 168 169 169 ARG ARG A . n 
A 1 169 ARG 169 170 170 ARG ARG A . n 
A 1 170 TYR 170 171 171 TYR TYR A . n 
A 1 171 LEU 171 172 172 LEU LEU A . n 
A 1 172 GLU 172 173 173 GLU GLU A . n 
A 1 173 ASN 173 174 174 ASN ASN A . n 
A 1 174 GLY 174 175 175 GLY GLY A . n 
A 1 175 LYS 175 176 176 LYS LYS A . n 
A 1 176 GLU 176 177 177 GLU GLU A . n 
A 1 177 THR 177 178 178 THR THR A . n 
A 1 178 LEU 178 179 179 LEU LEU A . n 
A 1 179 GLN 179 180 180 GLN GLN A . n 
A 1 180 ARG 180 181 181 ARG ARG A . n 
A 1 181 ALA 181 182 182 ALA ALA A . n 
A 1 182 GLU 182 183 183 GLU GLU A . n 
A 1 183 HIS 183 184 184 HIS HIS A . n 
A 1 184 PRO 184 185 185 PRO PRO A . n 
A 1 185 LYS 185 186 186 LYS LYS A . n 
A 1 186 THR 186 187 187 THR THR A . n 
A 1 187 HIS 187 188 188 HIS HIS A . n 
A 1 188 VAL 188 189 189 VAL VAL A . n 
A 1 189 THR 189 190 190 THR THR A . n 
A 1 190 HIS 190 191 191 HIS HIS A . n 
A 1 191 HIS 191 192 192 HIS HIS A . n 
A 1 192 PRO 192 193 193 PRO PRO A . n 
A 1 193 VAL 193 194 194 VAL VAL A . n 
A 1 194 SER 194 195 195 SER SER A . n 
A 1 195 ASP 195 196 196 ASP ASP A . n 
A 1 196 HIS 196 197 197 HIS HIS A . n 
A 1 197 GLU 197 198 198 GLU GLU A . n 
A 1 198 ALA 198 199 199 ALA ALA A . n 
A 1 199 THR 199 200 200 THR THR A . n 
A 1 200 LEU 200 201 201 LEU LEU A . n 
A 1 201 ARG 201 202 202 ARG ARG A . n 
A 1 202 CYS 202 203 203 CYS CYS A . n 
A 1 203 TRP 203 204 204 TRP TRP A . n 
A 1 204 ALA 204 205 205 ALA ALA A . n 
A 1 205 LEU 205 206 206 LEU LEU A . n 
A 1 206 GLY 206 207 207 GLY GLY A . n 
A 1 207 PHE 207 208 208 PHE PHE A . n 
A 1 208 TYR 208 209 209 TYR TYR A . n 
A 1 209 PRO 209 210 210 PRO PRO A . n 
A 1 210 ALA 210 211 211 ALA ALA A . n 
A 1 211 GLU 211 212 212 GLU GLU A . n 
A 1 212 ILE 212 213 213 ILE ILE A . n 
A 1 213 THR 213 214 214 THR THR A . n 
A 1 214 LEU 214 215 215 LEU LEU A . n 
A 1 215 THR 215 216 216 THR THR A . n 
A 1 216 TRP 216 217 217 TRP TRP A . n 
A 1 217 GLN 217 218 218 GLN GLN A . n 
A 1 218 ARG 218 219 219 ARG ARG A . n 
A 1 219 ASP 219 220 220 ASP ASP A . n 
A 1 220 GLY 220 221 221 GLY GLY A . n 
A 1 221 GLU 221 222 222 GLU GLU A . n 
A 1 222 ASP 222 223 223 ASP ASP A . n 
A 1 223 GLN 223 224 224 GLN GLN A . n 
A 1 224 THR 224 225 225 THR THR A . n 
A 1 225 GLN 225 226 226 GLN GLN A . n 
A 1 226 ASP 226 227 227 ASP ASP A . n 
A 1 227 THR 227 228 228 THR THR A . n 
A 1 228 GLU 228 229 229 GLU GLU A . n 
A 1 229 LEU 229 230 230 LEU LEU A . n 
A 1 230 VAL 230 231 231 VAL VAL A . n 
A 1 231 GLU 231 232 232 GLU GLU A . n 
A 1 232 THR 232 233 233 THR THR A . n 
A 1 233 ARG 233 234 234 ARG ARG A . n 
A 1 234 PRO 234 235 235 PRO PRO A . n 
A 1 235 ALA 235 236 236 ALA ALA A . n 
A 1 236 GLY 236 237 237 GLY GLY A . n 
A 1 237 ASP 237 238 238 ASP ASP A . n 
A 1 238 GLY 238 239 239 GLY GLY A . n 
A 1 239 THR 239 240 240 THR THR A . n 
A 1 240 PHE 240 241 241 PHE PHE A . n 
A 1 241 GLN 241 242 242 GLN GLN A . n 
A 1 242 LYS 242 243 243 LYS LYS A . n 
A 1 243 TRP 243 244 244 TRP TRP A . n 
A 1 244 ALA 244 245 245 ALA ALA A . n 
A 1 245 ALA 245 246 246 ALA ALA A . n 
A 1 246 VAL 246 247 247 VAL VAL A . n 
A 1 247 VAL 247 248 248 VAL VAL A . n 
A 1 248 VAL 248 249 249 VAL VAL A . n 
A 1 249 PRO 249 250 250 PRO PRO A . n 
A 1 250 SER 250 251 251 SER SER A . n 
A 1 251 GLY 251 252 252 GLY GLY A . n 
A 1 252 GLU 252 253 253 GLU GLU A . n 
A 1 253 GLU 253 254 254 GLU GLU A . n 
A 1 254 GLN 254 255 255 GLN GLN A . n 
A 1 255 ARG 255 256 256 ARG ARG A . n 
A 1 256 TYR 256 257 257 TYR TYR A . n 
A 1 257 THR 257 258 258 THR THR A . n 
A 1 258 CYS 258 259 259 CYS CYS A . n 
A 1 259 HIS 259 260 260 HIS HIS A . n 
A 1 260 VAL 260 261 261 VAL VAL A . n 
A 1 261 GLN 261 262 262 GLN GLN A . n 
A 1 262 HIS 262 263 263 HIS HIS A . n 
A 1 263 GLU 263 264 264 GLU GLU A . n 
A 1 264 GLY 264 265 265 GLY GLY A . n 
A 1 265 LEU 265 266 266 LEU LEU A . n 
A 1 266 PRO 266 267 267 PRO PRO A . n 
A 1 267 GLU 267 268 268 GLU GLU A . n 
A 1 268 PRO 268 269 269 PRO PRO A . n 
A 1 269 LEU 269 270 270 LEU LEU A . n 
A 1 270 THR 270 271 271 THR THR A . n 
A 1 271 LEU 271 272 272 LEU LEU A . n 
A 1 272 ARG 272 273 273 ARG ARG A . n 
A 1 273 TRP 273 274 274 TRP TRP A . n 
B 2 1   ILE 1   1   ?   ?   ?   B . n 
B 2 2   GLN 2   2   2   GLN GLN B . n 
B 2 3   ARG 3   3   3   ARG ARG B . n 
B 2 4   THR 4   4   4   THR THR B . n 
B 2 5   PRO 5   5   5   PRO PRO B . n 
B 2 6   LYS 6   6   6   LYS LYS B . n 
B 2 7   ILE 7   7   7   ILE ILE B . n 
B 2 8   GLN 8   8   8   GLN GLN B . n 
B 2 9   VAL 9   9   9   VAL VAL B . n 
B 2 10  TYR 10  10  10  TYR TYR B . n 
B 2 11  SER 11  11  11  SER SER B . n 
B 2 12  ARG 12  12  12  ARG ARG B . n 
B 2 13  HIS 13  13  13  HIS HIS B . n 
B 2 14  PRO 14  14  14  PRO PRO B . n 
B 2 15  ALA 15  15  15  ALA ALA B . n 
B 2 16  GLU 16  16  16  GLU GLU B . n 
B 2 17  ASN 17  17  17  ASN ASN B . n 
B 2 18  GLY 18  18  18  GLY GLY B . n 
B 2 19  LYS 19  19  19  LYS LYS B . n 
B 2 20  SER 20  20  20  SER SER B . n 
B 2 21  ASN 21  21  21  ASN ASN B . n 
B 2 22  PHE 22  22  22  PHE PHE B . n 
B 2 23  LEU 23  23  23  LEU LEU B . n 
B 2 24  ASN 24  24  24  ASN ASN B . n 
B 2 25  CYS 25  25  25  CYS CYS B . n 
B 2 26  TYR 26  26  26  TYR TYR B . n 
B 2 27  VAL 27  27  27  VAL VAL B . n 
B 2 28  SER 28  28  28  SER SER B . n 
B 2 29  GLY 29  29  29  GLY GLY B . n 
B 2 30  PHE 30  30  30  PHE PHE B . n 
B 2 31  HIS 31  31  31  HIS HIS B . n 
B 2 32  PRO 32  32  32  PRO PRO B . n 
B 2 33  SER 33  33  33  SER SER B . n 
B 2 34  ASP 34  34  34  ASP ASP B . n 
B 2 35  ILE 35  35  35  ILE ILE B . n 
B 2 36  GLU 36  36  36  GLU GLU B . n 
B 2 37  VAL 37  37  37  VAL VAL B . n 
B 2 38  ASP 38  38  38  ASP ASP B . n 
B 2 39  LEU 39  39  39  LEU LEU B . n 
B 2 40  LEU 40  40  40  LEU LEU B . n 
B 2 41  LYS 41  41  41  LYS LYS B . n 
B 2 42  ASN 42  42  42  ASN ASN B . n 
B 2 43  GLY 43  43  43  GLY GLY B . n 
B 2 44  GLU 44  44  44  GLU GLU B . n 
B 2 45  ARG 45  45  45  ARG ARG B . n 
B 2 46  ILE 46  46  46  ILE ILE B . n 
B 2 47  GLU 47  47  47  GLU GLU B . n 
B 2 48  LYS 48  48  48  LYS LYS B . n 
B 2 49  VAL 49  49  49  VAL VAL B . n 
B 2 50  GLU 50  50  50  GLU GLU B . n 
B 2 51  HIS 51  51  51  HIS HIS B . n 
B 2 52  SER 52  52  52  SER SER B . n 
B 2 53  ASP 53  53  53  ASP ASP B . n 
B 2 54  LEU 54  54  54  LEU LEU B . n 
B 2 55  SER 55  55  55  SER SER B . n 
B 2 56  PHE 56  56  56  PHE PHE B . n 
B 2 57  SER 57  57  57  SER SER B . n 
B 2 58  GLY 58  58  58  GLY GLY B . n 
B 2 59  ASP 59  59  59  ASP ASP B . n 
B 2 60  TRP 60  60  60  TRP TRP B . n 
B 2 61  SER 61  61  61  SER SER B . n 
B 2 62  PHE 62  62  62  PHE PHE B . n 
B 2 63  TYR 63  63  63  TYR TYR B . n 
B 2 64  LEU 64  64  64  LEU LEU B . n 
B 2 65  LEU 65  65  65  LEU LEU B . n 
B 2 66  TYR 66  66  66  TYR TYR B . n 
B 2 67  TYR 67  67  67  TYR TYR B . n 
B 2 68  THR 68  68  68  THR THR B . n 
B 2 69  GLU 69  69  69  GLU GLU B . n 
B 2 70  PHE 70  70  70  PHE PHE B . n 
B 2 71  THR 71  71  71  THR THR B . n 
B 2 72  PRO 72  72  72  PRO PRO B . n 
B 2 73  THR 73  73  73  THR THR B . n 
B 2 74  GLU 74  74  74  GLU GLU B . n 
B 2 75  LYS 75  75  75  LYS LYS B . n 
B 2 76  ASP 76  76  76  ASP ASP B . n 
B 2 77  GLU 77  77  77  GLU GLU B . n 
B 2 78  TYR 78  78  78  TYR TYR B . n 
B 2 79  ALA 79  79  79  ALA ALA B . n 
B 2 80  CYS 80  80  80  CYS CYS B . n 
B 2 81  ARG 81  81  81  ARG ARG B . n 
B 2 82  VAL 82  82  82  VAL VAL B . n 
B 2 83  ASN 83  83  83  ASN ASN B . n 
B 2 84  HIS 84  84  84  HIS HIS B . n 
B 2 85  VAL 85  85  85  VAL VAL B . n 
B 2 86  THR 86  86  86  THR THR B . n 
B 2 87  LEU 87  87  87  LEU LEU B . n 
B 2 88  SER 88  88  88  SER SER B . n 
B 2 89  GLN 89  89  89  GLN GLN B . n 
B 2 90  PRO 90  90  90  PRO PRO B . n 
B 2 91  LYS 91  91  91  LYS LYS B . n 
B 2 92  ILE 92  92  92  ILE ILE B . n 
B 2 93  VAL 93  93  93  VAL VAL B . n 
B 2 94  LYS 94  94  94  LYS LYS B . n 
B 2 95  TRP 95  95  95  TRP TRP B . n 
B 2 96  ASP 96  96  96  ASP ASP B . n 
B 2 97  ARG 97  97  97  ARG ARG B . n 
B 2 98  ASP 98  98  98  ASP ASP B . n 
B 2 99  MET 99  99  99  MET MET B . n 
C 3 1   MET 1   1   1   MET MET C . n 
C 3 2   ALA 2   2   2   ALA ALA C . n 
C 3 3   ARG 3   3   3   ARG ARG C . n 
C 3 4   GLU 4   4   4   GLU GLU C . n 
C 3 5   LEU 5   5   5   LEU LEU C . n 
C 3 6   HIS 6   6   6   HIS HIS C . n 
C 3 7   PRO 7   7   7   PRO PRO C . n 
C 3 8   GLU 8   8   8   GLU GLU C . n 
C 3 9   TYR 9   9   9   TYR TYR C . n 
D 1 1   SER 1   2   ?   ?   ?   D . n 
D 1 2   HIS 2   3   3   HIS HIS D . n 
D 1 3   SER 3   4   4   SER SER D . n 
D 1 4   MET 4   5   5   MET MET D . n 
D 1 5   ARG 5   6   6   ARG ARG D . n 
D 1 6   TYR 6   7   7   TYR TYR D . n 
D 1 7   PHE 7   8   8   PHE PHE D . n 
D 1 8   TYR 8   9   9   TYR TYR D . n 
D 1 9   THR 9   10  10  THR THR D . n 
D 1 10  ALA 10  11  11  ALA ALA D . n 
D 1 11  VAL 11  12  12  VAL VAL D . n 
D 1 12  SER 12  13  13  SER SER D . n 
D 1 13  ARG 13  14  14  ARG ARG D . n 
D 1 14  PRO 14  15  15  PRO PRO D . n 
D 1 15  GLY 15  16  16  GLY GLY D . n 
D 1 16  ARG 16  17  17  ARG ARG D . n 
D 1 17  GLY 17  18  18  GLY GLY D . n 
D 1 18  GLU 18  19  19  GLU GLU D . n 
D 1 19  PRO 19  20  20  PRO PRO D . n 
D 1 20  ARG 20  21  21  ARG ARG D . n 
D 1 21  PHE 21  22  22  PHE PHE D . n 
D 1 22  ILE 22  23  23  ILE ILE D . n 
D 1 23  ALA 23  24  24  ALA ALA D . n 
D 1 24  VAL 24  25  25  VAL VAL D . n 
D 1 25  GLY 25  26  26  GLY GLY D . n 
D 1 26  TYR 26  27  27  TYR TYR D . n 
D 1 27  VAL 27  28  28  VAL VAL D . n 
D 1 28  ASP 28  29  29  ASP ASP D . n 
D 1 29  ASP 29  30  30  ASP ASP D . n 
D 1 30  THR 30  31  31  THR THR D . n 
D 1 31  GLN 31  32  32  GLN GLN D . n 
D 1 32  PHE 32  33  33  PHE PHE D . n 
D 1 33  VAL 33  34  34  VAL VAL D . n 
D 1 34  ARG 34  35  35  ARG ARG D . n 
D 1 35  PHE 35  36  36  PHE PHE D . n 
D 1 36  ASP 36  37  37  ASP ASP D . n 
D 1 37  SER 37  38  38  SER SER D . n 
D 1 38  ASP 38  39  39  ASP ASP D . n 
D 1 39  ALA 39  40  40  ALA ALA D . n 
D 1 40  ALA 40  41  41  ALA ALA D . n 
D 1 41  SER 41  42  42  SER SER D . n 
D 1 42  PRO 42  43  43  PRO PRO D . n 
D 1 43  ARG 43  44  44  ARG ARG D . n 
D 1 44  GLY 44  45  45  GLY GLY D . n 
D 1 45  GLU 45  46  46  GLU GLU D . n 
D 1 46  PRO 46  47  47  PRO PRO D . n 
D 1 47  ARG 47  48  48  ARG ARG D . n 
D 1 48  ALA 48  49  49  ALA ALA D . n 
D 1 49  PRO 49  50  50  PRO PRO D . n 
D 1 50  TRP 50  51  51  TRP TRP D . n 
D 1 51  VAL 51  52  52  VAL VAL D . n 
D 1 52  GLU 52  53  53  GLU GLU D . n 
D 1 53  GLN 53  54  54  GLN GLN D . n 
D 1 54  GLU 54  55  55  GLU GLU D . n 
D 1 55  GLY 55  56  56  GLY GLY D . n 
D 1 56  PRO 56  57  57  PRO PRO D . n 
D 1 57  GLU 57  58  58  GLU GLU D . n 
D 1 58  TYR 58  59  59  TYR TYR D . n 
D 1 59  TRP 59  60  60  TRP TRP D . n 
D 1 60  ASP 60  61  61  ASP ASP D . n 
D 1 61  ARG 61  62  62  ARG ARG D . n 
D 1 62  GLU 62  63  63  GLU GLU D . n 
D 1 63  THR 63  64  64  THR THR D . n 
D 1 64  GLN 64  65  65  GLN GLN D . n 
D 1 65  LYS 65  66  66  LYS LYS D . n 
D 1 66  TYR 66  67  67  TYR TYR D . n 
D 1 67  LYS 67  68  68  LYS LYS D . n 
D 1 68  ARG 68  69  69  ARG ARG D . n 
D 1 69  GLN 69  70  70  GLN GLN D . n 
D 1 70  ALA 70  71  71  ALA ALA D . n 
D 1 71  GLN 71  72  72  GLN GLN D . n 
D 1 72  ALA 72  73  73  ALA ALA D . n 
D 1 73  ASP 73  74  74  ASP ASP D . n 
D 1 74  ARG 74  75  75  ARG ARG D . n 
D 1 75  VAL 75  76  76  VAL VAL D . n 
D 1 76  SER 76  77  77  SER SER D . n 
D 1 77  LEU 77  78  78  LEU LEU D . n 
D 1 78  ARG 78  79  79  ARG ARG D . n 
D 1 79  ASN 79  80  80  ASN ASN D . n 
D 1 80  LEU 80  81  81  LEU LEU D . n 
D 1 81  ARG 81  82  82  ARG ARG D . n 
D 1 82  GLY 82  83  83  GLY GLY D . n 
D 1 83  TYR 83  84  84  TYR TYR D . n 
D 1 84  TYR 84  85  85  TYR TYR D . n 
D 1 85  ASN 85  86  86  ASN ASN D . n 
D 1 86  GLN 86  87  87  GLN GLN D . n 
D 1 87  SER 87  88  88  SER SER D . n 
D 1 88  GLU 88  89  89  GLU GLU D . n 
D 1 89  ALA 89  90  90  ALA ALA D . n 
D 1 90  GLY 90  91  91  GLY GLY D . n 
D 1 91  SER 91  92  92  SER SER D . n 
D 1 92  HIS 92  93  93  HIS HIS D . n 
D 1 93  THR 93  94  94  THR THR D . n 
D 1 94  LEU 94  95  95  LEU LEU D . n 
D 1 95  GLN 95  96  96  GLN GLN D . n 
D 1 96  ARG 96  97  97  ARG ARG D . n 
D 1 97  MET 97  98  98  MET MET D . n 
D 1 98  TYR 98  99  99  TYR TYR D . n 
D 1 99  GLY 99  100 100 GLY GLY D . n 
D 1 100 CYS 100 101 101 CYS CYS D . n 
D 1 101 ASP 101 102 102 ASP ASP D . n 
D 1 102 LEU 102 103 103 LEU LEU D . n 
D 1 103 GLY 103 104 104 GLY GLY D . n 
D 1 104 PRO 104 105 105 PRO PRO D . n 
D 1 105 ASP 105 106 106 ASP ASP D . n 
D 1 106 GLY 106 107 107 GLY GLY D . n 
D 1 107 ARG 107 108 108 ARG ARG D . n 
D 1 108 LEU 108 109 109 LEU LEU D . n 
D 1 109 LEU 109 110 110 LEU LEU D . n 
D 1 110 ARG 110 111 111 ARG ARG D . n 
D 1 111 GLY 111 112 112 GLY GLY D . n 
D 1 112 TYR 112 113 113 TYR TYR D . n 
D 1 113 ASP 113 114 114 ASP ASP D . n 
D 1 114 GLN 114 115 115 GLN GLN D . n 
D 1 115 SER 115 116 116 SER SER D . n 
D 1 116 ALA 116 117 117 ALA ALA D . n 
D 1 117 TYR 117 118 118 TYR TYR D . n 
D 1 118 ASP 118 119 119 ASP ASP D . n 
D 1 119 GLY 119 120 120 GLY GLY D . n 
D 1 120 LYS 120 121 121 LYS LYS D . n 
D 1 121 ASP 121 122 122 ASP ASP D . n 
D 1 122 TYR 122 123 123 TYR TYR D . n 
D 1 123 ILE 123 124 124 ILE ILE D . n 
D 1 124 ALA 124 125 125 ALA ALA D . n 
D 1 125 LEU 125 126 126 LEU LEU D . n 
D 1 126 ASN 126 127 127 ASN ASN D . n 
D 1 127 GLU 127 128 128 GLU GLU D . n 
D 1 128 ASP 128 129 129 ASP ASP D . n 
D 1 129 LEU 129 130 130 LEU LEU D . n 
D 1 130 ARG 130 131 131 ARG ARG D . n 
D 1 131 SER 131 132 132 SER SER D . n 
D 1 132 TRP 132 133 133 TRP TRP D . n 
D 1 133 THR 133 134 134 THR THR D . n 
D 1 134 ALA 134 135 135 ALA ALA D . n 
D 1 135 ALA 135 136 136 ALA ALA D . n 
D 1 136 ASP 136 137 137 ASP ASP D . n 
D 1 137 THR 137 138 138 THR THR D . n 
D 1 138 ALA 138 139 139 ALA ALA D . n 
D 1 139 ALA 139 140 140 ALA ALA D . n 
D 1 140 GLN 140 141 141 GLN GLN D . n 
D 1 141 ILE 141 142 142 ILE ILE D . n 
D 1 142 THR 142 143 143 THR THR D . n 
D 1 143 GLN 143 144 144 GLN GLN D . n 
D 1 144 ARG 144 145 145 ARG ARG D . n 
D 1 145 LYS 145 146 146 LYS LYS D . n 
D 1 146 TRP 146 147 147 TRP TRP D . n 
D 1 147 GLU 147 148 148 GLU GLU D . n 
D 1 148 ALA 148 149 149 ALA ALA D . n 
D 1 149 ALA 149 150 150 ALA ALA D . n 
D 1 150 ARG 150 151 151 ARG ARG D . n 
D 1 151 GLU 151 152 152 GLU GLU D . n 
D 1 152 ALA 152 153 153 ALA ALA D . n 
D 1 153 GLU 153 154 154 GLU GLU D . n 
D 1 154 GLN 154 155 155 GLN GLN D . n 
D 1 155 TRP 155 156 156 TRP TRP D . n 
D 1 156 ARG 156 157 157 ARG ARG D . n 
D 1 157 ALA 157 158 158 ALA ALA D . n 
D 1 158 TYR 158 159 159 TYR TYR D . n 
D 1 159 LEU 159 160 160 LEU LEU D . n 
D 1 160 GLU 160 161 161 GLU GLU D . n 
D 1 161 GLY 161 162 162 GLY GLY D . n 
D 1 162 THR 162 163 163 THR THR D . n 
D 1 163 CYS 163 164 164 CYS CYS D . n 
D 1 164 VAL 164 165 165 VAL VAL D . n 
D 1 165 GLU 165 166 166 GLU GLU D . n 
D 1 166 TRP 166 167 167 TRP TRP D . n 
D 1 167 LEU 167 168 168 LEU LEU D . n 
D 1 168 ARG 168 169 169 ARG ARG D . n 
D 1 169 ARG 169 170 170 ARG ARG D . n 
D 1 170 TYR 170 171 171 TYR TYR D . n 
D 1 171 LEU 171 172 172 LEU LEU D . n 
D 1 172 GLU 172 173 173 GLU GLU D . n 
D 1 173 ASN 173 174 174 ASN ASN D . n 
D 1 174 GLY 174 175 175 GLY GLY D . n 
D 1 175 LYS 175 176 176 LYS LYS D . n 
D 1 176 GLU 176 177 177 GLU GLU D . n 
D 1 177 THR 177 178 178 THR THR D . n 
D 1 178 LEU 178 179 179 LEU LEU D . n 
D 1 179 GLN 179 180 180 GLN GLN D . n 
D 1 180 ARG 180 181 181 ARG ARG D . n 
D 1 181 ALA 181 182 182 ALA ALA D . n 
D 1 182 GLU 182 183 183 GLU GLU D . n 
D 1 183 HIS 183 184 184 HIS HIS D . n 
D 1 184 PRO 184 185 185 PRO PRO D . n 
D 1 185 LYS 185 186 186 LYS LYS D . n 
D 1 186 THR 186 187 187 THR THR D . n 
D 1 187 HIS 187 188 188 HIS HIS D . n 
D 1 188 VAL 188 189 189 VAL VAL D . n 
D 1 189 THR 189 190 190 THR THR D . n 
D 1 190 HIS 190 191 191 HIS HIS D . n 
D 1 191 HIS 191 192 192 HIS HIS D . n 
D 1 192 PRO 192 193 193 PRO PRO D . n 
D 1 193 VAL 193 194 194 VAL VAL D . n 
D 1 194 SER 194 195 195 SER SER D . n 
D 1 195 ASP 195 196 196 ASP ASP D . n 
D 1 196 HIS 196 197 197 HIS HIS D . n 
D 1 197 GLU 197 198 198 GLU GLU D . n 
D 1 198 ALA 198 199 199 ALA ALA D . n 
D 1 199 THR 199 200 200 THR THR D . n 
D 1 200 LEU 200 201 201 LEU LEU D . n 
D 1 201 ARG 201 202 202 ARG ARG D . n 
D 1 202 CYS 202 203 203 CYS CYS D . n 
D 1 203 TRP 203 204 204 TRP TRP D . n 
D 1 204 ALA 204 205 205 ALA ALA D . n 
D 1 205 LEU 205 206 206 LEU LEU D . n 
D 1 206 GLY 206 207 207 GLY GLY D . n 
D 1 207 PHE 207 208 208 PHE PHE D . n 
D 1 208 TYR 208 209 209 TYR TYR D . n 
D 1 209 PRO 209 210 210 PRO PRO D . n 
D 1 210 ALA 210 211 211 ALA ALA D . n 
D 1 211 GLU 211 212 212 GLU GLU D . n 
D 1 212 ILE 212 213 213 ILE ILE D . n 
D 1 213 THR 213 214 214 THR THR D . n 
D 1 214 LEU 214 215 215 LEU LEU D . n 
D 1 215 THR 215 216 216 THR THR D . n 
D 1 216 TRP 216 217 217 TRP TRP D . n 
D 1 217 GLN 217 218 218 GLN GLN D . n 
D 1 218 ARG 218 219 219 ARG ARG D . n 
D 1 219 ASP 219 220 220 ASP ASP D . n 
D 1 220 GLY 220 221 221 GLY GLY D . n 
D 1 221 GLU 221 222 222 GLU GLU D . n 
D 1 222 ASP 222 223 223 ASP ASP D . n 
D 1 223 GLN 223 224 224 GLN GLN D . n 
D 1 224 THR 224 225 225 THR THR D . n 
D 1 225 GLN 225 226 226 GLN GLN D . n 
D 1 226 ASP 226 227 227 ASP ASP D . n 
D 1 227 THR 227 228 228 THR THR D . n 
D 1 228 GLU 228 229 229 GLU GLU D . n 
D 1 229 LEU 229 230 230 LEU LEU D . n 
D 1 230 VAL 230 231 231 VAL VAL D . n 
D 1 231 GLU 231 232 232 GLU GLU D . n 
D 1 232 THR 232 233 233 THR THR D . n 
D 1 233 ARG 233 234 234 ARG ARG D . n 
D 1 234 PRO 234 235 235 PRO PRO D . n 
D 1 235 ALA 235 236 236 ALA ALA D . n 
D 1 236 GLY 236 237 237 GLY GLY D . n 
D 1 237 ASP 237 238 238 ASP ASP D . n 
D 1 238 GLY 238 239 239 GLY GLY D . n 
D 1 239 THR 239 240 240 THR THR D . n 
D 1 240 PHE 240 241 241 PHE PHE D . n 
D 1 241 GLN 241 242 242 GLN GLN D . n 
D 1 242 LYS 242 243 243 LYS LYS D . n 
D 1 243 TRP 243 244 244 TRP TRP D . n 
D 1 244 ALA 244 245 245 ALA ALA D . n 
D 1 245 ALA 245 246 246 ALA ALA D . n 
D 1 246 VAL 246 247 247 VAL VAL D . n 
D 1 247 VAL 247 248 248 VAL VAL D . n 
D 1 248 VAL 248 249 249 VAL VAL D . n 
D 1 249 PRO 249 250 250 PRO PRO D . n 
D 1 250 SER 250 251 251 SER SER D . n 
D 1 251 GLY 251 252 252 GLY GLY D . n 
D 1 252 GLU 252 253 253 GLU GLU D . n 
D 1 253 GLU 253 254 254 GLU GLU D . n 
D 1 254 GLN 254 255 255 GLN GLN D . n 
D 1 255 ARG 255 256 256 ARG ARG D . n 
D 1 256 TYR 256 257 257 TYR TYR D . n 
D 1 257 THR 257 258 258 THR THR D . n 
D 1 258 CYS 258 259 259 CYS CYS D . n 
D 1 259 HIS 259 260 260 HIS HIS D . n 
D 1 260 VAL 260 261 261 VAL VAL D . n 
D 1 261 GLN 261 262 262 GLN GLN D . n 
D 1 262 HIS 262 263 263 HIS HIS D . n 
D 1 263 GLU 263 264 264 GLU GLU D . n 
D 1 264 GLY 264 265 265 GLY GLY D . n 
D 1 265 LEU 265 266 266 LEU LEU D . n 
D 1 266 PRO 266 267 267 PRO PRO D . n 
D 1 267 GLU 267 268 268 GLU GLU D . n 
D 1 268 PRO 268 269 269 PRO PRO D . n 
D 1 269 LEU 269 270 270 LEU LEU D . n 
D 1 270 THR 270 271 271 THR THR D . n 
D 1 271 LEU 271 272 272 LEU LEU D . n 
D 1 272 ARG 272 273 273 ARG ARG D . n 
D 1 273 TRP 273 274 274 TRP TRP D . n 
E 2 1   ILE 1   1   1   ILE ILE E . n 
E 2 2   GLN 2   2   2   GLN GLN E . n 
E 2 3   ARG 3   3   3   ARG ARG E . n 
E 2 4   THR 4   4   4   THR THR E . n 
E 2 5   PRO 5   5   5   PRO PRO E . n 
E 2 6   LYS 6   6   6   LYS LYS E . n 
E 2 7   ILE 7   7   7   ILE ILE E . n 
E 2 8   GLN 8   8   8   GLN GLN E . n 
E 2 9   VAL 9   9   9   VAL VAL E . n 
E 2 10  TYR 10  10  10  TYR TYR E . n 
E 2 11  SER 11  11  11  SER SER E . n 
E 2 12  ARG 12  12  12  ARG ARG E . n 
E 2 13  HIS 13  13  13  HIS HIS E . n 
E 2 14  PRO 14  14  14  PRO PRO E . n 
E 2 15  ALA 15  15  15  ALA ALA E . n 
E 2 16  GLU 16  16  16  GLU GLU E . n 
E 2 17  ASN 17  17  17  ASN ASN E . n 
E 2 18  GLY 18  18  18  GLY GLY E . n 
E 2 19  LYS 19  19  19  LYS LYS E . n 
E 2 20  SER 20  20  20  SER SER E . n 
E 2 21  ASN 21  21  21  ASN ASN E . n 
E 2 22  PHE 22  22  22  PHE PHE E . n 
E 2 23  LEU 23  23  23  LEU LEU E . n 
E 2 24  ASN 24  24  24  ASN ASN E . n 
E 2 25  CYS 25  25  25  CYS CYS E . n 
E 2 26  TYR 26  26  26  TYR TYR E . n 
E 2 27  VAL 27  27  27  VAL VAL E . n 
E 2 28  SER 28  28  28  SER SER E . n 
E 2 29  GLY 29  29  29  GLY GLY E . n 
E 2 30  PHE 30  30  30  PHE PHE E . n 
E 2 31  HIS 31  31  31  HIS HIS E . n 
E 2 32  PRO 32  32  32  PRO PRO E . n 
E 2 33  SER 33  33  33  SER SER E . n 
E 2 34  ASP 34  34  34  ASP ASP E . n 
E 2 35  ILE 35  35  35  ILE ILE E . n 
E 2 36  GLU 36  36  36  GLU GLU E . n 
E 2 37  VAL 37  37  37  VAL VAL E . n 
E 2 38  ASP 38  38  38  ASP ASP E . n 
E 2 39  LEU 39  39  39  LEU LEU E . n 
E 2 40  LEU 40  40  40  LEU LEU E . n 
E 2 41  LYS 41  41  41  LYS LYS E . n 
E 2 42  ASN 42  42  42  ASN ASN E . n 
E 2 43  GLY 43  43  43  GLY GLY E . n 
E 2 44  GLU 44  44  44  GLU GLU E . n 
E 2 45  ARG 45  45  45  ARG ARG E . n 
E 2 46  ILE 46  46  46  ILE ILE E . n 
E 2 47  GLU 47  47  47  GLU GLU E . n 
E 2 48  LYS 48  48  48  LYS LYS E . n 
E 2 49  VAL 49  49  49  VAL VAL E . n 
E 2 50  GLU 50  50  50  GLU GLU E . n 
E 2 51  HIS 51  51  51  HIS HIS E . n 
E 2 52  SER 52  52  52  SER SER E . n 
E 2 53  ASP 53  53  53  ASP ASP E . n 
E 2 54  LEU 54  54  54  LEU LEU E . n 
E 2 55  SER 55  55  55  SER SER E . n 
E 2 56  PHE 56  56  56  PHE PHE E . n 
E 2 57  SER 57  57  57  SER SER E . n 
E 2 58  GLY 58  58  58  GLY GLY E . n 
E 2 59  ASP 59  59  59  ASP ASP E . n 
E 2 60  TRP 60  60  60  TRP TRP E . n 
E 2 61  SER 61  61  61  SER SER E . n 
E 2 62  PHE 62  62  62  PHE PHE E . n 
E 2 63  TYR 63  63  63  TYR TYR E . n 
E 2 64  LEU 64  64  64  LEU LEU E . n 
E 2 65  LEU 65  65  65  LEU LEU E . n 
E 2 66  TYR 66  66  66  TYR TYR E . n 
E 2 67  TYR 67  67  67  TYR TYR E . n 
E 2 68  THR 68  68  68  THR THR E . n 
E 2 69  GLU 69  69  69  GLU GLU E . n 
E 2 70  PHE 70  70  70  PHE PHE E . n 
E 2 71  THR 71  71  71  THR THR E . n 
E 2 72  PRO 72  72  72  PRO PRO E . n 
E 2 73  THR 73  73  73  THR THR E . n 
E 2 74  GLU 74  74  74  GLU GLU E . n 
E 2 75  LYS 75  75  75  LYS LYS E . n 
E 2 76  ASP 76  76  76  ASP ASP E . n 
E 2 77  GLU 77  77  77  GLU GLU E . n 
E 2 78  TYR 78  78  78  TYR TYR E . n 
E 2 79  ALA 79  79  79  ALA ALA E . n 
E 2 80  CYS 80  80  80  CYS CYS E . n 
E 2 81  ARG 81  81  81  ARG ARG E . n 
E 2 82  VAL 82  82  82  VAL VAL E . n 
E 2 83  ASN 83  83  83  ASN ASN E . n 
E 2 84  HIS 84  84  84  HIS HIS E . n 
E 2 85  VAL 85  85  85  VAL VAL E . n 
E 2 86  THR 86  86  86  THR THR E . n 
E 2 87  LEU 87  87  87  LEU LEU E . n 
E 2 88  SER 88  88  88  SER SER E . n 
E 2 89  GLN 89  89  89  GLN GLN E . n 
E 2 90  PRO 90  90  90  PRO PRO E . n 
E 2 91  LYS 91  91  91  LYS LYS E . n 
E 2 92  ILE 92  92  92  ILE ILE E . n 
E 2 93  VAL 93  93  93  VAL VAL E . n 
E 2 94  LYS 94  94  94  LYS LYS E . n 
E 2 95  TRP 95  95  95  TRP TRP E . n 
E 2 96  ASP 96  96  96  ASP ASP E . n 
E 2 97  ARG 97  97  97  ARG ARG E . n 
E 2 98  ASP 98  98  98  ASP ASP E . n 
E 2 99  MET 99  99  99  MET MET E . n 
F 3 1   MET 1   1   1   MET MET F . n 
F 3 2   ALA 2   2   2   ALA ALA F . n 
F 3 3   ARG 3   3   3   ARG ARG F . n 
F 3 4   GLU 4   4   4   GLU GLU F . n 
F 3 5   LEU 5   5   5   LEU LEU F . n 
F 3 6   HIS 6   6   6   HIS HIS F . n 
F 3 7   PRO 7   7   7   PRO PRO F . n 
F 3 8   GLU 8   8   8   GLU GLU F . n 
F 3 9   TYR 9   9   9   TYR TYR F . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
G 4 HOH 1   301 77   HOH HOH A . 
G 4 HOH 2   302 146  HOH HOH A . 
G 4 HOH 3   303 1072 HOH HOH A . 
G 4 HOH 4   304 507  HOH HOH A . 
G 4 HOH 5   305 34   HOH HOH A . 
G 4 HOH 6   306 1004 HOH HOH A . 
G 4 HOH 7   307 261  HOH HOH A . 
G 4 HOH 8   308 518  HOH HOH A . 
G 4 HOH 9   309 647  HOH HOH A . 
G 4 HOH 10  310 228  HOH HOH A . 
G 4 HOH 11  311 168  HOH HOH A . 
G 4 HOH 12  312 443  HOH HOH A . 
G 4 HOH 13  313 247  HOH HOH A . 
G 4 HOH 14  314 551  HOH HOH A . 
G 4 HOH 15  315 862  HOH HOH A . 
G 4 HOH 16  316 967  HOH HOH A . 
G 4 HOH 17  317 453  HOH HOH A . 
G 4 HOH 18  318 53   HOH HOH A . 
G 4 HOH 19  319 318  HOH HOH A . 
G 4 HOH 20  320 68   HOH HOH A . 
G 4 HOH 21  321 72   HOH HOH A . 
G 4 HOH 22  322 697  HOH HOH A . 
G 4 HOH 23  323 39   HOH HOH A . 
G 4 HOH 24  324 459  HOH HOH A . 
G 4 HOH 25  325 624  HOH HOH A . 
G 4 HOH 26  326 788  HOH HOH A . 
G 4 HOH 27  327 41   HOH HOH A . 
G 4 HOH 28  328 10   HOH HOH A . 
G 4 HOH 29  329 121  HOH HOH A . 
G 4 HOH 30  330 478  HOH HOH A . 
G 4 HOH 31  331 869  HOH HOH A . 
G 4 HOH 32  332 94   HOH HOH A . 
G 4 HOH 33  333 635  HOH HOH A . 
G 4 HOH 34  334 546  HOH HOH A . 
G 4 HOH 35  335 854  HOH HOH A . 
G 4 HOH 36  336 1077 HOH HOH A . 
G 4 HOH 37  337 207  HOH HOH A . 
G 4 HOH 38  338 371  HOH HOH A . 
G 4 HOH 39  339 21   HOH HOH A . 
G 4 HOH 40  340 186  HOH HOH A . 
G 4 HOH 41  341 209  HOH HOH A . 
G 4 HOH 42  342 188  HOH HOH A . 
G 4 HOH 43  343 434  HOH HOH A . 
G 4 HOH 44  344 69   HOH HOH A . 
G 4 HOH 45  345 276  HOH HOH A . 
G 4 HOH 46  346 1013 HOH HOH A . 
G 4 HOH 47  347 619  HOH HOH A . 
G 4 HOH 48  348 15   HOH HOH A . 
G 4 HOH 49  349 358  HOH HOH A . 
G 4 HOH 50  350 118  HOH HOH A . 
G 4 HOH 51  351 151  HOH HOH A . 
G 4 HOH 52  352 32   HOH HOH A . 
G 4 HOH 53  353 437  HOH HOH A . 
G 4 HOH 54  354 147  HOH HOH A . 
G 4 HOH 55  355 781  HOH HOH A . 
G 4 HOH 56  356 56   HOH HOH A . 
G 4 HOH 57  357 763  HOH HOH A . 
G 4 HOH 58  358 656  HOH HOH A . 
G 4 HOH 59  359 560  HOH HOH A . 
G 4 HOH 60  360 17   HOH HOH A . 
G 4 HOH 61  361 27   HOH HOH A . 
G 4 HOH 62  362 972  HOH HOH A . 
G 4 HOH 63  363 698  HOH HOH A . 
G 4 HOH 64  364 367  HOH HOH A . 
G 4 HOH 65  365 38   HOH HOH A . 
G 4 HOH 66  366 735  HOH HOH A . 
G 4 HOH 67  367 24   HOH HOH A . 
G 4 HOH 68  368 383  HOH HOH A . 
G 4 HOH 69  369 493  HOH HOH A . 
G 4 HOH 70  370 613  HOH HOH A . 
G 4 HOH 71  371 832  HOH HOH A . 
G 4 HOH 72  372 780  HOH HOH A . 
G 4 HOH 73  373 499  HOH HOH A . 
G 4 HOH 74  374 239  HOH HOH A . 
G 4 HOH 75  375 1061 HOH HOH A . 
G 4 HOH 76  376 445  HOH HOH A . 
G 4 HOH 77  377 617  HOH HOH A . 
G 4 HOH 78  378 369  HOH HOH A . 
G 4 HOH 79  379 726  HOH HOH A . 
G 4 HOH 80  380 1001 HOH HOH A . 
G 4 HOH 81  381 302  HOH HOH A . 
G 4 HOH 82  382 350  HOH HOH A . 
G 4 HOH 83  383 183  HOH HOH A . 
G 4 HOH 84  384 555  HOH HOH A . 
G 4 HOH 85  385 12   HOH HOH A . 
G 4 HOH 86  386 550  HOH HOH A . 
G 4 HOH 87  387 58   HOH HOH A . 
G 4 HOH 88  388 903  HOH HOH A . 
G 4 HOH 89  389 37   HOH HOH A . 
G 4 HOH 90  390 424  HOH HOH A . 
G 4 HOH 91  391 231  HOH HOH A . 
G 4 HOH 92  392 66   HOH HOH A . 
G 4 HOH 93  393 694  HOH HOH A . 
G 4 HOH 94  394 182  HOH HOH A . 
G 4 HOH 95  395 833  HOH HOH A . 
G 4 HOH 96  396 489  HOH HOH A . 
G 4 HOH 97  397 627  HOH HOH A . 
G 4 HOH 98  398 173  HOH HOH A . 
G 4 HOH 99  399 959  HOH HOH A . 
G 4 HOH 100 400 354  HOH HOH A . 
G 4 HOH 101 401 431  HOH HOH A . 
G 4 HOH 102 402 167  HOH HOH A . 
G 4 HOH 103 403 275  HOH HOH A . 
G 4 HOH 104 404 871  HOH HOH A . 
G 4 HOH 105 405 242  HOH HOH A . 
G 4 HOH 106 406 880  HOH HOH A . 
G 4 HOH 107 407 858  HOH HOH A . 
G 4 HOH 108 408 181  HOH HOH A . 
G 4 HOH 109 409 948  HOH HOH A . 
G 4 HOH 110 410 471  HOH HOH A . 
G 4 HOH 111 411 4    HOH HOH A . 
G 4 HOH 112 412 908  HOH HOH A . 
G 4 HOH 113 413 219  HOH HOH A . 
G 4 HOH 114 414 784  HOH HOH A . 
G 4 HOH 115 415 225  HOH HOH A . 
G 4 HOH 116 416 630  HOH HOH A . 
G 4 HOH 117 417 141  HOH HOH A . 
G 4 HOH 118 418 782  HOH HOH A . 
G 4 HOH 119 419 1008 HOH HOH A . 
G 4 HOH 120 420 393  HOH HOH A . 
G 4 HOH 121 421 1090 HOH HOH A . 
G 4 HOH 122 422 136  HOH HOH A . 
G 4 HOH 123 423 170  HOH HOH A . 
G 4 HOH 124 424 137  HOH HOH A . 
G 4 HOH 125 425 1    HOH HOH A . 
G 4 HOH 126 426 149  HOH HOH A . 
G 4 HOH 127 427 342  HOH HOH A . 
G 4 HOH 128 428 931  HOH HOH A . 
G 4 HOH 129 429 22   HOH HOH A . 
G 4 HOH 130 430 920  HOH HOH A . 
G 4 HOH 131 431 269  HOH HOH A . 
G 4 HOH 132 432 530  HOH HOH A . 
G 4 HOH 133 433 417  HOH HOH A . 
G 4 HOH 134 434 683  HOH HOH A . 
G 4 HOH 135 435 826  HOH HOH A . 
G 4 HOH 136 436 126  HOH HOH A . 
G 4 HOH 137 437 135  HOH HOH A . 
G 4 HOH 138 438 311  HOH HOH A . 
G 4 HOH 139 439 357  HOH HOH A . 
G 4 HOH 140 440 508  HOH HOH A . 
G 4 HOH 141 441 675  HOH HOH A . 
G 4 HOH 142 442 800  HOH HOH A . 
G 4 HOH 143 443 986  HOH HOH A . 
G 4 HOH 144 444 292  HOH HOH A . 
G 4 HOH 145 445 240  HOH HOH A . 
G 4 HOH 146 446 514  HOH HOH A . 
G 4 HOH 147 447 78   HOH HOH A . 
G 4 HOH 148 448 1000 HOH HOH A . 
G 4 HOH 149 449 374  HOH HOH A . 
G 4 HOH 150 450 172  HOH HOH A . 
G 4 HOH 151 451 1070 HOH HOH A . 
G 4 HOH 152 452 692  HOH HOH A . 
G 4 HOH 153 453 895  HOH HOH A . 
G 4 HOH 154 454 837  HOH HOH A . 
G 4 HOH 155 455 440  HOH HOH A . 
G 4 HOH 156 456 377  HOH HOH A . 
G 4 HOH 157 457 103  HOH HOH A . 
G 4 HOH 158 458 446  HOH HOH A . 
G 4 HOH 159 459 378  HOH HOH A . 
G 4 HOH 160 460 894  HOH HOH A . 
G 4 HOH 161 461 822  HOH HOH A . 
G 4 HOH 162 462 480  HOH HOH A . 
G 4 HOH 163 463 660  HOH HOH A . 
G 4 HOH 164 464 592  HOH HOH A . 
G 4 HOH 165 465 447  HOH HOH A . 
G 4 HOH 166 466 750  HOH HOH A . 
G 4 HOH 167 467 339  HOH HOH A . 
G 4 HOH 168 468 328  HOH HOH A . 
G 4 HOH 169 469 178  HOH HOH A . 
G 4 HOH 170 470 534  HOH HOH A . 
G 4 HOH 171 471 1045 HOH HOH A . 
G 4 HOH 172 472 366  HOH HOH A . 
G 4 HOH 173 473 659  HOH HOH A . 
G 4 HOH 174 474 1041 HOH HOH A . 
G 4 HOH 175 475 938  HOH HOH A . 
G 4 HOH 176 476 581  HOH HOH A . 
G 4 HOH 177 477 159  HOH HOH A . 
G 4 HOH 178 478 556  HOH HOH A . 
G 4 HOH 179 479 702  HOH HOH A . 
G 4 HOH 180 480 953  HOH HOH A . 
G 4 HOH 181 481 1058 HOH HOH A . 
G 4 HOH 182 482 700  HOH HOH A . 
G 4 HOH 183 483 226  HOH HOH A . 
G 4 HOH 184 484 1056 HOH HOH A . 
G 4 HOH 185 485 910  HOH HOH A . 
G 4 HOH 186 486 280  HOH HOH A . 
G 4 HOH 187 487 515  HOH HOH A . 
G 4 HOH 188 488 1053 HOH HOH A . 
G 4 HOH 189 489 764  HOH HOH A . 
G 4 HOH 190 490 305  HOH HOH A . 
G 4 HOH 191 491 1042 HOH HOH A . 
G 4 HOH 192 492 588  HOH HOH A . 
G 4 HOH 193 493 648  HOH HOH A . 
G 4 HOH 194 494 293  HOH HOH A . 
G 4 HOH 195 495 998  HOH HOH A . 
G 4 HOH 196 496 336  HOH HOH A . 
G 4 HOH 197 497 511  HOH HOH A . 
G 4 HOH 198 498 704  HOH HOH A . 
G 4 HOH 199 499 549  HOH HOH A . 
G 4 HOH 200 500 930  HOH HOH A . 
G 4 HOH 201 501 1088 HOH HOH A . 
G 4 HOH 202 502 610  HOH HOH A . 
G 4 HOH 203 503 1085 HOH HOH A . 
G 4 HOH 204 504 753  HOH HOH A . 
G 4 HOH 205 505 830  HOH HOH A . 
G 4 HOH 206 506 760  HOH HOH A . 
G 4 HOH 207 507 203  HOH HOH A . 
G 4 HOH 208 508 941  HOH HOH A . 
G 4 HOH 209 509 813  HOH HOH A . 
G 4 HOH 210 510 664  HOH HOH A . 
G 4 HOH 211 511 411  HOH HOH A . 
G 4 HOH 212 512 646  HOH HOH A . 
G 4 HOH 213 513 309  HOH HOH A . 
G 4 HOH 214 514 524  HOH HOH A . 
G 4 HOH 215 515 333  HOH HOH A . 
G 4 HOH 216 516 865  HOH HOH A . 
G 4 HOH 217 517 961  HOH HOH A . 
G 4 HOH 218 518 955  HOH HOH A . 
G 4 HOH 219 519 688  HOH HOH A . 
G 4 HOH 220 520 1044 HOH HOH A . 
G 4 HOH 221 521 1063 HOH HOH A . 
G 4 HOH 222 522 863  HOH HOH A . 
G 4 HOH 223 523 403  HOH HOH A . 
G 4 HOH 224 524 522  HOH HOH A . 
G 4 HOH 225 525 1047 HOH HOH A . 
G 4 HOH 226 526 821  HOH HOH A . 
G 4 HOH 227 527 160  HOH HOH A . 
G 4 HOH 228 528 847  HOH HOH A . 
G 4 HOH 229 529 460  HOH HOH A . 
G 4 HOH 230 530 868  HOH HOH A . 
G 4 HOH 231 531 1022 HOH HOH A . 
G 4 HOH 232 532 625  HOH HOH A . 
G 4 HOH 233 533 1027 HOH HOH A . 
G 4 HOH 234 534 157  HOH HOH A . 
G 4 HOH 235 535 1039 HOH HOH A . 
G 4 HOH 236 536 916  HOH HOH A . 
G 4 HOH 237 537 621  HOH HOH A . 
G 4 HOH 238 538 603  HOH HOH A . 
G 4 HOH 239 539 1091 HOH HOH A . 
G 4 HOH 240 540 887  HOH HOH A . 
G 4 HOH 241 541 628  HOH HOH A . 
G 4 HOH 242 542 1071 HOH HOH A . 
G 4 HOH 243 543 899  HOH HOH A . 
G 4 HOH 244 544 828  HOH HOH A . 
G 4 HOH 245 545 824  HOH HOH A . 
G 4 HOH 246 546 327  HOH HOH A . 
G 4 HOH 247 547 994  HOH HOH A . 
G 4 HOH 248 548 883  HOH HOH A . 
G 4 HOH 249 549 758  HOH HOH A . 
G 4 HOH 250 550 185  HOH HOH A . 
G 4 HOH 251 551 975  HOH HOH A . 
G 4 HOH 252 552 640  HOH HOH A . 
G 4 HOH 253 553 391  HOH HOH A . 
G 4 HOH 254 554 464  HOH HOH A . 
G 4 HOH 255 555 653  HOH HOH A . 
G 4 HOH 256 556 878  HOH HOH A . 
G 4 HOH 257 557 839  HOH HOH A . 
G 4 HOH 258 558 335  HOH HOH A . 
G 4 HOH 259 559 989  HOH HOH A . 
G 4 HOH 260 560 928  HOH HOH A . 
G 4 HOH 261 561 981  HOH HOH A . 
G 4 HOH 262 562 166  HOH HOH A . 
G 4 HOH 263 563 1051 HOH HOH A . 
G 4 HOH 264 564 418  HOH HOH A . 
G 4 HOH 265 565 601  HOH HOH A . 
G 4 HOH 266 566 801  HOH HOH A . 
G 4 HOH 267 567 1033 HOH HOH A . 
G 4 HOH 268 568 789  HOH HOH A . 
G 4 HOH 269 569 436  HOH HOH A . 
G 4 HOH 270 570 473  HOH HOH A . 
G 4 HOH 271 571 685  HOH HOH A . 
G 4 HOH 272 572 946  HOH HOH A . 
G 4 HOH 273 573 600  HOH HOH A . 
G 4 HOH 274 574 483  HOH HOH A . 
G 4 HOH 275 575 216  HOH HOH A . 
G 4 HOH 276 576 631  HOH HOH A . 
G 4 HOH 277 577 997  HOH HOH A . 
G 4 HOH 278 578 650  HOH HOH A . 
G 4 HOH 279 579 542  HOH HOH A . 
G 4 HOH 280 580 1065 HOH HOH A . 
G 4 HOH 281 581 816  HOH HOH A . 
G 4 HOH 282 582 583  HOH HOH A . 
G 4 HOH 283 583 765  HOH HOH A . 
G 4 HOH 284 584 926  HOH HOH A . 
G 4 HOH 285 585 642  HOH HOH A . 
G 4 HOH 286 586 406  HOH HOH A . 
G 4 HOH 287 587 851  HOH HOH A . 
G 4 HOH 288 588 752  HOH HOH A . 
G 4 HOH 289 589 649  HOH HOH A . 
G 4 HOH 290 590 918  HOH HOH A . 
G 4 HOH 291 591 731  HOH HOH A . 
G 4 HOH 292 592 790  HOH HOH A . 
G 4 HOH 293 593 695  HOH HOH A . 
G 4 HOH 294 594 187  HOH HOH A . 
G 4 HOH 295 595 867  HOH HOH A . 
G 4 HOH 296 596 353  HOH HOH A . 
G 4 HOH 297 597 969  HOH HOH A . 
G 4 HOH 298 598 263  HOH HOH A . 
G 4 HOH 299 599 1018 HOH HOH A . 
G 4 HOH 300 600 690  HOH HOH A . 
G 4 HOH 301 601 677  HOH HOH A . 
G 4 HOH 302 602 400  HOH HOH A . 
G 4 HOH 303 603 221  HOH HOH A . 
G 4 HOH 304 604 532  HOH HOH A . 
G 4 HOH 305 605 974  HOH HOH A . 
G 4 HOH 306 606 467  HOH HOH A . 
G 4 HOH 307 607 720  HOH HOH A . 
G 4 HOH 308 608 441  HOH HOH A . 
G 4 HOH 309 609 1049 HOH HOH A . 
G 4 HOH 310 610 1067 HOH HOH A . 
G 4 HOH 311 611 1015 HOH HOH A . 
G 4 HOH 312 612 1011 HOH HOH A . 
H 4 HOH 1   101 793  HOH HOH B . 
H 4 HOH 2   102 679  HOH HOH B . 
H 4 HOH 3   103 410  HOH HOH B . 
H 4 HOH 4   104 498  HOH HOH B . 
H 4 HOH 5   105 577  HOH HOH B . 
H 4 HOH 6   106 579  HOH HOH B . 
H 4 HOH 7   107 745  HOH HOH B . 
H 4 HOH 8   108 947  HOH HOH B . 
H 4 HOH 9   109 934  HOH HOH B . 
H 4 HOH 10  110 206  HOH HOH B . 
H 4 HOH 11  111 244  HOH HOH B . 
H 4 HOH 12  112 62   HOH HOH B . 
H 4 HOH 13  113 213  HOH HOH B . 
H 4 HOH 14  114 284  HOH HOH B . 
H 4 HOH 15  115 897  HOH HOH B . 
H 4 HOH 16  116 958  HOH HOH B . 
H 4 HOH 17  117 364  HOH HOH B . 
H 4 HOH 18  118 300  HOH HOH B . 
H 4 HOH 19  119 177  HOH HOH B . 
H 4 HOH 20  120 273  HOH HOH B . 
H 4 HOH 21  121 329  HOH HOH B . 
H 4 HOH 22  122 97   HOH HOH B . 
H 4 HOH 23  123 719  HOH HOH B . 
H 4 HOH 24  124 71   HOH HOH B . 
H 4 HOH 25  125 33   HOH HOH B . 
H 4 HOH 26  126 615  HOH HOH B . 
H 4 HOH 27  127 898  HOH HOH B . 
H 4 HOH 28  128 51   HOH HOH B . 
H 4 HOH 29  129 727  HOH HOH B . 
H 4 HOH 30  130 682  HOH HOH B . 
H 4 HOH 31  131 890  HOH HOH B . 
H 4 HOH 32  132 110  HOH HOH B . 
H 4 HOH 33  133 491  HOH HOH B . 
H 4 HOH 34  134 739  HOH HOH B . 
H 4 HOH 35  135 321  HOH HOH B . 
H 4 HOH 36  136 709  HOH HOH B . 
H 4 HOH 37  137 220  HOH HOH B . 
H 4 HOH 38  138 45   HOH HOH B . 
H 4 HOH 39  139 343  HOH HOH B . 
H 4 HOH 40  140 73   HOH HOH B . 
H 4 HOH 41  141 618  HOH HOH B . 
H 4 HOH 42  142 112  HOH HOH B . 
H 4 HOH 43  143 314  HOH HOH B . 
H 4 HOH 44  144 91   HOH HOH B . 
H 4 HOH 45  145 42   HOH HOH B . 
H 4 HOH 46  146 249  HOH HOH B . 
H 4 HOH 47  147 116  HOH HOH B . 
H 4 HOH 48  148 433  HOH HOH B . 
H 4 HOH 49  149 274  HOH HOH B . 
H 4 HOH 50  150 270  HOH HOH B . 
H 4 HOH 51  151 733  HOH HOH B . 
H 4 HOH 52  152 315  HOH HOH B . 
H 4 HOH 53  153 521  HOH HOH B . 
H 4 HOH 54  154 808  HOH HOH B . 
H 4 HOH 55  155 450  HOH HOH B . 
H 4 HOH 56  156 384  HOH HOH B . 
H 4 HOH 57  157 67   HOH HOH B . 
H 4 HOH 58  158 133  HOH HOH B . 
H 4 HOH 59  159 235  HOH HOH B . 
H 4 HOH 60  160 900  HOH HOH B . 
H 4 HOH 61  161 46   HOH HOH B . 
H 4 HOH 62  162 670  HOH HOH B . 
H 4 HOH 63  163 191  HOH HOH B . 
H 4 HOH 64  164 106  HOH HOH B . 
H 4 HOH 65  165 531  HOH HOH B . 
H 4 HOH 66  166 132  HOH HOH B . 
H 4 HOH 67  167 529  HOH HOH B . 
H 4 HOH 68  168 768  HOH HOH B . 
H 4 HOH 69  169 1082 HOH HOH B . 
H 4 HOH 70  170 475  HOH HOH B . 
H 4 HOH 71  171 864  HOH HOH B . 
H 4 HOH 72  172 298  HOH HOH B . 
H 4 HOH 73  173 296  HOH HOH B . 
H 4 HOH 74  174 786  HOH HOH B . 
H 4 HOH 75  175 180  HOH HOH B . 
H 4 HOH 76  176 492  HOH HOH B . 
H 4 HOH 77  177 85   HOH HOH B . 
H 4 HOH 78  178 590  HOH HOH B . 
H 4 HOH 79  179 107  HOH HOH B . 
H 4 HOH 80  180 245  HOH HOH B . 
H 4 HOH 81  181 150  HOH HOH B . 
H 4 HOH 82  182 80   HOH HOH B . 
H 4 HOH 83  183 456  HOH HOH B . 
H 4 HOH 84  184 561  HOH HOH B . 
H 4 HOH 85  185 214  HOH HOH B . 
H 4 HOH 86  186 111  HOH HOH B . 
H 4 HOH 87  187 174  HOH HOH B . 
H 4 HOH 88  188 330  HOH HOH B . 
H 4 HOH 89  189 268  HOH HOH B . 
H 4 HOH 90  190 286  HOH HOH B . 
H 4 HOH 91  191 901  HOH HOH B . 
H 4 HOH 92  192 732  HOH HOH B . 
H 4 HOH 93  193 90   HOH HOH B . 
H 4 HOH 94  194 461  HOH HOH B . 
H 4 HOH 95  195 923  HOH HOH B . 
H 4 HOH 96  196 1035 HOH HOH B . 
H 4 HOH 97  197 527  HOH HOH B . 
H 4 HOH 98  198 227  HOH HOH B . 
H 4 HOH 99  199 982  HOH HOH B . 
H 4 HOH 100 200 827  HOH HOH B . 
H 4 HOH 101 201 70   HOH HOH B . 
H 4 HOH 102 202 516  HOH HOH B . 
H 4 HOH 103 203 370  HOH HOH B . 
H 4 HOH 104 204 463  HOH HOH B . 
H 4 HOH 105 205 375  HOH HOH B . 
H 4 HOH 106 206 442  HOH HOH B . 
H 4 HOH 107 207 723  HOH HOH B . 
H 4 HOH 108 208 639  HOH HOH B . 
H 4 HOH 109 209 836  HOH HOH B . 
H 4 HOH 110 210 710  HOH HOH B . 
H 4 HOH 111 211 535  HOH HOH B . 
H 4 HOH 112 212 580  HOH HOH B . 
H 4 HOH 113 213 356  HOH HOH B . 
H 4 HOH 114 214 387  HOH HOH B . 
H 4 HOH 115 215 96   HOH HOH B . 
H 4 HOH 116 216 1014 HOH HOH B . 
H 4 HOH 117 217 540  HOH HOH B . 
H 4 HOH 118 218 1003 HOH HOH B . 
H 4 HOH 119 219 924  HOH HOH B . 
H 4 HOH 120 220 877  HOH HOH B . 
H 4 HOH 121 221 870  HOH HOH B . 
H 4 HOH 122 222 427  HOH HOH B . 
H 4 HOH 123 223 669  HOH HOH B . 
H 4 HOH 124 224 935  HOH HOH B . 
H 4 HOH 125 225 849  HOH HOH B . 
H 4 HOH 126 226 979  HOH HOH B . 
H 4 HOH 127 227 486  HOH HOH B . 
H 4 HOH 128 228 655  HOH HOH B . 
H 4 HOH 129 229 978  HOH HOH B . 
H 4 HOH 130 230 477  HOH HOH B . 
H 4 HOH 131 231 939  HOH HOH B . 
H 4 HOH 132 232 905  HOH HOH B . 
H 4 HOH 133 233 537  HOH HOH B . 
H 4 HOH 134 234 1084 HOH HOH B . 
H 4 HOH 135 235 1016 HOH HOH B . 
H 4 HOH 136 236 678  HOH HOH B . 
H 4 HOH 137 237 576  HOH HOH B . 
H 4 HOH 138 238 1064 HOH HOH B . 
H 4 HOH 139 239 176  HOH HOH B . 
H 4 HOH 140 240 717  HOH HOH B . 
H 4 HOH 141 241 728  HOH HOH B . 
H 4 HOH 142 242 945  HOH HOH B . 
H 4 HOH 143 243 819  HOH HOH B . 
H 4 HOH 144 244 419  HOH HOH B . 
H 4 HOH 145 245 528  HOH HOH B . 
H 4 HOH 146 246 509  HOH HOH B . 
H 4 HOH 147 247 351  HOH HOH B . 
H 4 HOH 148 248 715  HOH HOH B . 
H 4 HOH 149 249 751  HOH HOH B . 
H 4 HOH 150 250 539  HOH HOH B . 
H 4 HOH 151 251 506  HOH HOH B . 
H 4 HOH 152 252 902  HOH HOH B . 
H 4 HOH 153 253 856  HOH HOH B . 
H 4 HOH 154 254 1055 HOH HOH B . 
H 4 HOH 155 255 267  HOH HOH B . 
H 4 HOH 156 256 313  HOH HOH B . 
I 4 HOH 1   101 423  HOH HOH C . 
I 4 HOH 2   102 379  HOH HOH C . 
I 4 HOH 3   103 79   HOH HOH C . 
I 4 HOH 4   104 93   HOH HOH C . 
I 4 HOH 5   105 142  HOH HOH C . 
I 4 HOH 6   106 153  HOH HOH C . 
I 4 HOH 7   107 217  HOH HOH C . 
I 4 HOH 8   108 87   HOH HOH C . 
I 4 HOH 9   109 340  HOH HOH C . 
I 4 HOH 10  110 365  HOH HOH C . 
I 4 HOH 11  111 76   HOH HOH C . 
I 4 HOH 12  112 161  HOH HOH C . 
I 4 HOH 13  113 567  HOH HOH C . 
I 4 HOH 14  114 696  HOH HOH C . 
I 4 HOH 15  115 229  HOH HOH C . 
I 4 HOH 16  116 520  HOH HOH C . 
I 4 HOH 17  117 787  HOH HOH C . 
I 4 HOH 18  118 641  HOH HOH C . 
I 4 HOH 19  119 512  HOH HOH C . 
I 4 HOH 20  120 988  HOH HOH C . 
I 4 HOH 21  121 658  HOH HOH C . 
J 4 HOH 1   301 970  HOH HOH D . 
J 4 HOH 2   302 547  HOH HOH D . 
J 4 HOH 3   303 114  HOH HOH D . 
J 4 HOH 4   304 602  HOH HOH D . 
J 4 HOH 5   305 482  HOH HOH D . 
J 4 HOH 6   306 686  HOH HOH D . 
J 4 HOH 7   307 287  HOH HOH D . 
J 4 HOH 8   308 501  HOH HOH D . 
J 4 HOH 9   309 1028 HOH HOH D . 
J 4 HOH 10  310 487  HOH HOH D . 
J 4 HOH 11  311 545  HOH HOH D . 
J 4 HOH 12  312 55   HOH HOH D . 
J 4 HOH 13  313 1032 HOH HOH D . 
J 4 HOH 14  314 237  HOH HOH D . 
J 4 HOH 15  315 43   HOH HOH D . 
J 4 HOH 16  316 382  HOH HOH D . 
J 4 HOH 17  317 288  HOH HOH D . 
J 4 HOH 18  318 596  HOH HOH D . 
J 4 HOH 19  319 991  HOH HOH D . 
J 4 HOH 20  320 7    HOH HOH D . 
J 4 HOH 21  321 593  HOH HOH D . 
J 4 HOH 22  322 3    HOH HOH D . 
J 4 HOH 23  323 1059 HOH HOH D . 
J 4 HOH 24  324 729  HOH HOH D . 
J 4 HOH 25  325 334  HOH HOH D . 
J 4 HOH 26  326 1080 HOH HOH D . 
J 4 HOH 27  327 571  HOH HOH D . 
J 4 HOH 28  328 16   HOH HOH D . 
J 4 HOH 29  329 591  HOH HOH D . 
J 4 HOH 30  330 325  HOH HOH D . 
J 4 HOH 31  331 29   HOH HOH D . 
J 4 HOH 32  332 401  HOH HOH D . 
J 4 HOH 33  333 1074 HOH HOH D . 
J 4 HOH 34  334 179  HOH HOH D . 
J 4 HOH 35  335 932  HOH HOH D . 
J 4 HOH 36  336 2    HOH HOH D . 
J 4 HOH 37  337 212  HOH HOH D . 
J 4 HOH 38  338 14   HOH HOH D . 
J 4 HOH 39  339 838  HOH HOH D . 
J 4 HOH 40  340 557  HOH HOH D . 
J 4 HOH 41  341 164  HOH HOH D . 
J 4 HOH 42  342 452  HOH HOH D . 
J 4 HOH 43  343 241  HOH HOH D . 
J 4 HOH 44  344 138  HOH HOH D . 
J 4 HOH 45  345 341  HOH HOH D . 
J 4 HOH 46  346 611  HOH HOH D . 
J 4 HOH 47  347 200  HOH HOH D . 
J 4 HOH 48  348 825  HOH HOH D . 
J 4 HOH 49  349 795  HOH HOH D . 
J 4 HOH 50  350 9    HOH HOH D . 
J 4 HOH 51  351 940  HOH HOH D . 
J 4 HOH 52  352 184  HOH HOH D . 
J 4 HOH 53  353 57   HOH HOH D . 
J 4 HOH 54  354 18   HOH HOH D . 
J 4 HOH 55  355 224  HOH HOH D . 
J 4 HOH 56  356 64   HOH HOH D . 
J 4 HOH 57  357 5    HOH HOH D . 
J 4 HOH 58  358 48   HOH HOH D . 
J 4 HOH 59  359 796  HOH HOH D . 
J 4 HOH 60  360 49   HOH HOH D . 
J 4 HOH 61  361 992  HOH HOH D . 
J 4 HOH 62  362 113  HOH HOH D . 
J 4 HOH 63  363 538  HOH HOH D . 
J 4 HOH 64  364 915  HOH HOH D . 
J 4 HOH 65  365 766  HOH HOH D . 
J 4 HOH 66  366 30   HOH HOH D . 
J 4 HOH 67  367 201  HOH HOH D . 
J 4 HOH 68  368 60   HOH HOH D . 
J 4 HOH 69  369 778  HOH HOH D . 
J 4 HOH 70  370 140  HOH HOH D . 
J 4 HOH 71  371 913  HOH HOH D . 
J 4 HOH 72  372 131  HOH HOH D . 
J 4 HOH 73  373 134  HOH HOH D . 
J 4 HOH 74  374 20   HOH HOH D . 
J 4 HOH 75  375 279  HOH HOH D . 
J 4 HOH 76  376 199  HOH HOH D . 
J 4 HOH 77  377 54   HOH HOH D . 
J 4 HOH 78  378 385  HOH HOH D . 
J 4 HOH 79  379 306  HOH HOH D . 
J 4 HOH 80  380 331  HOH HOH D . 
J 4 HOH 81  381 672  HOH HOH D . 
J 4 HOH 82  382 841  HOH HOH D . 
J 4 HOH 83  383 361  HOH HOH D . 
J 4 HOH 84  384 171  HOH HOH D . 
J 4 HOH 85  385 312  HOH HOH D . 
J 4 HOH 86  386 204  HOH HOH D . 
J 4 HOH 87  387 19   HOH HOH D . 
J 4 HOH 88  388 40   HOH HOH D . 
J 4 HOH 89  389 154  HOH HOH D . 
J 4 HOH 90  390 193  HOH HOH D . 
J 4 HOH 91  391 11   HOH HOH D . 
J 4 HOH 92  392 81   HOH HOH D . 
J 4 HOH 93  393 102  HOH HOH D . 
J 4 HOH 94  394 100  HOH HOH D . 
J 4 HOH 95  395 840  HOH HOH D . 
J 4 HOH 96  396 61   HOH HOH D . 
J 4 HOH 97  397 500  HOH HOH D . 
J 4 HOH 98  398 255  HOH HOH D . 
J 4 HOH 99  399 609  HOH HOH D . 
J 4 HOH 100 400 156  HOH HOH D . 
J 4 HOH 101 401 104  HOH HOH D . 
J 4 HOH 102 402 927  HOH HOH D . 
J 4 HOH 103 403 889  HOH HOH D . 
J 4 HOH 104 404 265  HOH HOH D . 
J 4 HOH 105 405 523  HOH HOH D . 
J 4 HOH 106 406 130  HOH HOH D . 
J 4 HOH 107 407 163  HOH HOH D . 
J 4 HOH 108 408 1087 HOH HOH D . 
J 4 HOH 109 409 23   HOH HOH D . 
J 4 HOH 110 410 35   HOH HOH D . 
J 4 HOH 111 411 449  HOH HOH D . 
J 4 HOH 112 412 896  HOH HOH D . 
J 4 HOH 113 413 282  HOH HOH D . 
J 4 HOH 114 414 623  HOH HOH D . 
J 4 HOH 115 415 218  HOH HOH D . 
J 4 HOH 116 416 502  HOH HOH D . 
J 4 HOH 117 417 425  HOH HOH D . 
J 4 HOH 118 418 36   HOH HOH D . 
J 4 HOH 119 419 722  HOH HOH D . 
J 4 HOH 120 420 775  HOH HOH D . 
J 4 HOH 121 421 65   HOH HOH D . 
J 4 HOH 122 422 75   HOH HOH D . 
J 4 HOH 123 423 422  HOH HOH D . 
J 4 HOH 124 424 964  HOH HOH D . 
J 4 HOH 125 425 6    HOH HOH D . 
J 4 HOH 126 426 544  HOH HOH D . 
J 4 HOH 127 427 607  HOH HOH D . 
J 4 HOH 128 428 256  HOH HOH D . 
J 4 HOH 129 429 949  HOH HOH D . 
J 4 HOH 130 430 562  HOH HOH D . 
J 4 HOH 131 431 74   HOH HOH D . 
J 4 HOH 132 432 362  HOH HOH D . 
J 4 HOH 133 433 139  HOH HOH D . 
J 4 HOH 134 434 310  HOH HOH D . 
J 4 HOH 135 435 852  HOH HOH D . 
J 4 HOH 136 436 84   HOH HOH D . 
J 4 HOH 137 437 1086 HOH HOH D . 
J 4 HOH 138 438 693  HOH HOH D . 
J 4 HOH 139 439 779  HOH HOH D . 
J 4 HOH 140 440 99   HOH HOH D . 
J 4 HOH 141 441 637  HOH HOH D . 
J 4 HOH 142 442 108  HOH HOH D . 
J 4 HOH 143 443 308  HOH HOH D . 
J 4 HOH 144 444 260  HOH HOH D . 
J 4 HOH 145 445 359  HOH HOH D . 
J 4 HOH 146 446 86   HOH HOH D . 
J 4 HOH 147 447 554  HOH HOH D . 
J 4 HOH 148 448 8    HOH HOH D . 
J 4 HOH 149 449 82   HOH HOH D . 
J 4 HOH 150 450 485  HOH HOH D . 
J 4 HOH 151 451 770  HOH HOH D . 
J 4 HOH 152 452 439  HOH HOH D . 
J 4 HOH 153 453 1012 HOH HOH D . 
J 4 HOH 154 454 243  HOH HOH D . 
J 4 HOH 155 455 349  HOH HOH D . 
J 4 HOH 156 456 668  HOH HOH D . 
J 4 HOH 157 457 205  HOH HOH D . 
J 4 HOH 158 458 574  HOH HOH D . 
J 4 HOH 159 459 809  HOH HOH D . 
J 4 HOH 160 460 257  HOH HOH D . 
J 4 HOH 161 461 1029 HOH HOH D . 
J 4 HOH 162 462 399  HOH HOH D . 
J 4 HOH 163 463 162  HOH HOH D . 
J 4 HOH 164 464 783  HOH HOH D . 
J 4 HOH 165 465 303  HOH HOH D . 
J 4 HOH 166 466 194  HOH HOH D . 
J 4 HOH 167 467 466  HOH HOH D . 
J 4 HOH 168 468 397  HOH HOH D . 
J 4 HOH 169 469 89   HOH HOH D . 
J 4 HOH 170 470 337  HOH HOH D . 
J 4 HOH 171 471 911  HOH HOH D . 
J 4 HOH 172 472 413  HOH HOH D . 
J 4 HOH 173 473 283  HOH HOH D . 
J 4 HOH 174 474 345  HOH HOH D . 
J 4 HOH 175 475 115  HOH HOH D . 
J 4 HOH 176 476 323  HOH HOH D . 
J 4 HOH 177 477 44   HOH HOH D . 
J 4 HOH 178 478 1068 HOH HOH D . 
J 4 HOH 179 479 957  HOH HOH D . 
J 4 HOH 180 480 980  HOH HOH D . 
J 4 HOH 181 481 144  HOH HOH D . 
J 4 HOH 182 482 533  HOH HOH D . 
J 4 HOH 183 483 355  HOH HOH D . 
J 4 HOH 184 484 281  HOH HOH D . 
J 4 HOH 185 485 1025 HOH HOH D . 
J 4 HOH 186 486 657  HOH HOH D . 
J 4 HOH 187 487 785  HOH HOH D . 
J 4 HOH 188 488 208  HOH HOH D . 
J 4 HOH 189 489 468  HOH HOH D . 
J 4 HOH 190 490 230  HOH HOH D . 
J 4 HOH 191 491 246  HOH HOH D . 
J 4 HOH 192 492 105  HOH HOH D . 
J 4 HOH 193 493 88   HOH HOH D . 
J 4 HOH 194 494 368  HOH HOH D . 
J 4 HOH 195 495 233  HOH HOH D . 
J 4 HOH 196 496 409  HOH HOH D . 
J 4 HOH 197 497 488  HOH HOH D . 
J 4 HOH 198 498 1089 HOH HOH D . 
J 4 HOH 199 499 1034 HOH HOH D . 
J 4 HOH 200 500 190  HOH HOH D . 
J 4 HOH 201 501 198  HOH HOH D . 
J 4 HOH 202 502 454  HOH HOH D . 
J 4 HOH 203 503 587  HOH HOH D . 
J 4 HOH 204 504 158  HOH HOH D . 
J 4 HOH 205 505 812  HOH HOH D . 
J 4 HOH 206 506 817  HOH HOH D . 
J 4 HOH 207 507 741  HOH HOH D . 
J 4 HOH 208 508 1023 HOH HOH D . 
J 4 HOH 209 509 834  HOH HOH D . 
J 4 HOH 210 510 644  HOH HOH D . 
J 4 HOH 211 511 632  HOH HOH D . 
J 4 HOH 212 512 122  HOH HOH D . 
J 4 HOH 213 513 95   HOH HOH D . 
J 4 HOH 214 514 676  HOH HOH D . 
J 4 HOH 215 515 604  HOH HOH D . 
J 4 HOH 216 516 408  HOH HOH D . 
J 4 HOH 217 517 743  HOH HOH D . 
J 4 HOH 218 518 472  HOH HOH D . 
J 4 HOH 219 519 297  HOH HOH D . 
J 4 HOH 220 520 513  HOH HOH D . 
J 4 HOH 221 521 262  HOH HOH D . 
J 4 HOH 222 522 120  HOH HOH D . 
J 4 HOH 223 523 708  HOH HOH D . 
J 4 HOH 224 524 651  HOH HOH D . 
J 4 HOH 225 525 1009 HOH HOH D . 
J 4 HOH 226 526 388  HOH HOH D . 
J 4 HOH 227 527 960  HOH HOH D . 
J 4 HOH 228 528 31   HOH HOH D . 
J 4 HOH 229 529 320  HOH HOH D . 
J 4 HOH 230 530 797  HOH HOH D . 
J 4 HOH 231 531 848  HOH HOH D . 
J 4 HOH 232 532 835  HOH HOH D . 
J 4 HOH 233 533 749  HOH HOH D . 
J 4 HOH 234 534 222  HOH HOH D . 
J 4 HOH 235 535 143  HOH HOH D . 
J 4 HOH 236 536 324  HOH HOH D . 
J 4 HOH 237 537 1005 HOH HOH D . 
J 4 HOH 238 538 26   HOH HOH D . 
J 4 HOH 239 539 850  HOH HOH D . 
J 4 HOH 240 540 519  HOH HOH D . 
J 4 HOH 241 541 860  HOH HOH D . 
J 4 HOH 242 542 614  HOH HOH D . 
J 4 HOH 243 543 301  HOH HOH D . 
J 4 HOH 244 544 490  HOH HOH D . 
J 4 HOH 245 545 891  HOH HOH D . 
J 4 HOH 246 546 451  HOH HOH D . 
J 4 HOH 247 547 444  HOH HOH D . 
J 4 HOH 248 548 495  HOH HOH D . 
J 4 HOH 249 549 123  HOH HOH D . 
J 4 HOH 250 550 504  HOH HOH D . 
J 4 HOH 251 551 277  HOH HOH D . 
J 4 HOH 252 552 1073 HOH HOH D . 
J 4 HOH 253 553 470  HOH HOH D . 
J 4 HOH 254 554 844  HOH HOH D . 
J 4 HOH 255 555 416  HOH HOH D . 
J 4 HOH 256 556 754  HOH HOH D . 
J 4 HOH 257 557 634  HOH HOH D . 
J 4 HOH 258 558 1050 HOH HOH D . 
J 4 HOH 259 559 1054 HOH HOH D . 
J 4 HOH 260 560 904  HOH HOH D . 
J 4 HOH 261 561 990  HOH HOH D . 
J 4 HOH 262 562 791  HOH HOH D . 
J 4 HOH 263 563 405  HOH HOH D . 
J 4 HOH 264 564 873  HOH HOH D . 
J 4 HOH 265 565 861  HOH HOH D . 
J 4 HOH 266 566 703  HOH HOH D . 
J 4 HOH 267 567 510  HOH HOH D . 
J 4 HOH 268 568 933  HOH HOH D . 
J 4 HOH 269 569 465  HOH HOH D . 
J 4 HOH 270 570 584  HOH HOH D . 
J 4 HOH 271 571 457  HOH HOH D . 
J 4 HOH 272 572 1038 HOH HOH D . 
J 4 HOH 273 573 398  HOH HOH D . 
J 4 HOH 274 574 1075 HOH HOH D . 
J 4 HOH 275 575 169  HOH HOH D . 
J 4 HOH 276 576 372  HOH HOH D . 
J 4 HOH 277 577 738  HOH HOH D . 
J 4 HOH 278 578 517  HOH HOH D . 
J 4 HOH 279 579 853  HOH HOH D . 
J 4 HOH 280 580 792  HOH HOH D . 
J 4 HOH 281 581 1007 HOH HOH D . 
J 4 HOH 282 582 536  HOH HOH D . 
J 4 HOH 283 583 396  HOH HOH D . 
J 4 HOH 284 584 767  HOH HOH D . 
J 4 HOH 285 585 842  HOH HOH D . 
J 4 HOH 286 586 438  HOH HOH D . 
J 4 HOH 287 587 730  HOH HOH D . 
J 4 HOH 288 588 319  HOH HOH D . 
J 4 HOH 289 589 573  HOH HOH D . 
J 4 HOH 290 590 586  HOH HOH D . 
J 4 HOH 291 591 691  HOH HOH D . 
J 4 HOH 292 592 575  HOH HOH D . 
J 4 HOH 293 593 322  HOH HOH D . 
J 4 HOH 294 594 711  HOH HOH D . 
J 4 HOH 295 595 985  HOH HOH D . 
J 4 HOH 296 596 124  HOH HOH D . 
J 4 HOH 297 597 885  HOH HOH D . 
J 4 HOH 298 598 757  HOH HOH D . 
J 4 HOH 299 599 599  HOH HOH D . 
J 4 HOH 300 600 1043 HOH HOH D . 
J 4 HOH 301 601 713  HOH HOH D . 
J 4 HOH 302 602 373  HOH HOH D . 
J 4 HOH 303 603 597  HOH HOH D . 
J 4 HOH 304 604 211  HOH HOH D . 
J 4 HOH 305 605 829  HOH HOH D . 
J 4 HOH 306 606 666  HOH HOH D . 
J 4 HOH 307 607 1036 HOH HOH D . 
J 4 HOH 308 608 810  HOH HOH D . 
J 4 HOH 309 609 394  HOH HOH D . 
J 4 HOH 310 610 798  HOH HOH D . 
J 4 HOH 311 611 956  HOH HOH D . 
J 4 HOH 312 612 762  HOH HOH D . 
J 4 HOH 313 613 563  HOH HOH D . 
J 4 HOH 314 614 1024 HOH HOH D . 
J 4 HOH 315 615 612  HOH HOH D . 
J 4 HOH 316 616 736  HOH HOH D . 
J 4 HOH 317 617 776  HOH HOH D . 
J 4 HOH 318 618 197  HOH HOH D . 
J 4 HOH 319 619 846  HOH HOH D . 
J 4 HOH 320 620 568  HOH HOH D . 
J 4 HOH 321 621 347  HOH HOH D . 
J 4 HOH 322 622 663  HOH HOH D . 
J 4 HOH 323 623 922  HOH HOH D . 
J 4 HOH 324 624 598  HOH HOH D . 
J 4 HOH 325 625 553  HOH HOH D . 
J 4 HOH 326 626 195  HOH HOH D . 
J 4 HOH 327 627 654  HOH HOH D . 
J 4 HOH 328 628 497  HOH HOH D . 
J 4 HOH 329 629 189  HOH HOH D . 
J 4 HOH 330 630 906  HOH HOH D . 
J 4 HOH 331 631 1052 HOH HOH D . 
J 4 HOH 332 632 705  HOH HOH D . 
J 4 HOH 333 633 462  HOH HOH D . 
J 4 HOH 334 634 843  HOH HOH D . 
J 4 HOH 335 635 881  HOH HOH D . 
J 4 HOH 336 636 196  HOH HOH D . 
J 4 HOH 337 637 278  HOH HOH D . 
J 4 HOH 338 638 352  HOH HOH D . 
J 4 HOH 339 639 962  HOH HOH D . 
J 4 HOH 340 640 866  HOH HOH D . 
J 4 HOH 341 641 414  HOH HOH D . 
J 4 HOH 342 642 266  HOH HOH D . 
J 4 HOH 343 643 503  HOH HOH D . 
J 4 HOH 344 644 811  HOH HOH D . 
J 4 HOH 345 645 469  HOH HOH D . 
J 4 HOH 346 646 737  HOH HOH D . 
J 4 HOH 347 647 543  HOH HOH D . 
J 4 HOH 348 648 390  HOH HOH D . 
J 4 HOH 349 649 643  HOH HOH D . 
J 4 HOH 350 650 404  HOH HOH D . 
J 4 HOH 351 651 973  HOH HOH D . 
J 4 HOH 352 652 875  HOH HOH D . 
J 4 HOH 353 653 317  HOH HOH D . 
J 4 HOH 354 654 402  HOH HOH D . 
J 4 HOH 355 655 772  HOH HOH D . 
J 4 HOH 356 656 1017 HOH HOH D . 
J 4 HOH 357 657 253  HOH HOH D . 
J 4 HOH 358 658 995  HOH HOH D . 
J 4 HOH 359 659 1031 HOH HOH D . 
J 4 HOH 360 660 1078 HOH HOH D . 
J 4 HOH 361 661 326  HOH HOH D . 
J 4 HOH 362 662 572  HOH HOH D . 
J 4 HOH 363 663 1020 HOH HOH D . 
J 4 HOH 364 664 968  HOH HOH D . 
J 4 HOH 365 665 771  HOH HOH D . 
J 4 HOH 366 666 412  HOH HOH D . 
J 4 HOH 367 667 721  HOH HOH D . 
J 4 HOH 368 668 929  HOH HOH D . 
J 4 HOH 369 669 389  HOH HOH D . 
J 4 HOH 370 670 1069 HOH HOH D . 
J 4 HOH 371 671 606  HOH HOH D . 
J 4 HOH 372 672 1030 HOH HOH D . 
J 4 HOH 373 673 1019 HOH HOH D . 
J 4 HOH 374 674 1010 HOH HOH D . 
J 4 HOH 375 675 747  HOH HOH D . 
K 4 HOH 1   101 993  HOH HOH E . 
K 4 HOH 2   102 744  HOH HOH E . 
K 4 HOH 3   103 1026 HOH HOH E . 
K 4 HOH 4   104 608  HOH HOH E . 
K 4 HOH 5   105 432  HOH HOH E . 
K 4 HOH 6   106 259  HOH HOH E . 
K 4 HOH 7   107 152  HOH HOH E . 
K 4 HOH 8   108 718  HOH HOH E . 
K 4 HOH 9   109 101  HOH HOH E . 
K 4 HOH 10  110 420  HOH HOH E . 
K 4 HOH 11  111 815  HOH HOH E . 
K 4 HOH 12  112 360  HOH HOH E . 
K 4 HOH 13  113 977  HOH HOH E . 
K 4 HOH 14  114 594  HOH HOH E . 
K 4 HOH 15  115 831  HOH HOH E . 
K 4 HOH 16  116 381  HOH HOH E . 
K 4 HOH 17  117 13   HOH HOH E . 
K 4 HOH 18  118 392  HOH HOH E . 
K 4 HOH 19  119 845  HOH HOH E . 
K 4 HOH 20  120 344  HOH HOH E . 
K 4 HOH 21  121 264  HOH HOH E . 
K 4 HOH 22  122 566  HOH HOH E . 
K 4 HOH 23  123 415  HOH HOH E . 
K 4 HOH 24  124 629  HOH HOH E . 
K 4 HOH 25  125 155  HOH HOH E . 
K 4 HOH 26  126 674  HOH HOH E . 
K 4 HOH 27  127 638  HOH HOH E . 
K 4 HOH 28  128 794  HOH HOH E . 
K 4 HOH 29  129 667  HOH HOH E . 
K 4 HOH 30  130 250  HOH HOH E . 
K 4 HOH 31  131 165  HOH HOH E . 
K 4 HOH 32  132 714  HOH HOH E . 
K 4 HOH 33  133 28   HOH HOH E . 
K 4 HOH 34  134 569  HOH HOH E . 
K 4 HOH 35  135 295  HOH HOH E . 
K 4 HOH 36  136 248  HOH HOH E . 
K 4 HOH 37  137 942  HOH HOH E . 
K 4 HOH 38  138 914  HOH HOH E . 
K 4 HOH 39  139 963  HOH HOH E . 
K 4 HOH 40  140 578  HOH HOH E . 
K 4 HOH 41  141 294  HOH HOH E . 
K 4 HOH 42  142 232  HOH HOH E . 
K 4 HOH 43  143 252  HOH HOH E . 
K 4 HOH 44  144 971  HOH HOH E . 
K 4 HOH 45  145 505  HOH HOH E . 
K 4 HOH 46  146 455  HOH HOH E . 
K 4 HOH 47  147 684  HOH HOH E . 
K 4 HOH 48  148 936  HOH HOH E . 
K 4 HOH 49  149 564  HOH HOH E . 
K 4 HOH 50  150 479  HOH HOH E . 
K 4 HOH 51  151 50   HOH HOH E . 
K 4 HOH 52  152 565  HOH HOH E . 
K 4 HOH 53  153 346  HOH HOH E . 
K 4 HOH 54  154 996  HOH HOH E . 
K 4 HOH 55  155 430  HOH HOH E . 
K 4 HOH 56  156 777  HOH HOH E . 
K 4 HOH 57  157 435  HOH HOH E . 
K 4 HOH 58  158 290  HOH HOH E . 
K 4 HOH 59  159 548  HOH HOH E . 
K 4 HOH 60  160 251  HOH HOH E . 
K 4 HOH 61  161 724  HOH HOH E . 
K 4 HOH 62  162 258  HOH HOH E . 
K 4 HOH 63  163 874  HOH HOH E . 
K 4 HOH 64  164 1006 HOH HOH E . 
K 4 HOH 65  165 912  HOH HOH E . 
K 4 HOH 66  166 25   HOH HOH E . 
K 4 HOH 67  167 541  HOH HOH E . 
K 4 HOH 68  168 937  HOH HOH E . 
K 4 HOH 69  169 145  HOH HOH E . 
K 4 HOH 70  170 148  HOH HOH E . 
K 4 HOH 71  171 289  HOH HOH E . 
K 4 HOH 72  172 119  HOH HOH E . 
K 4 HOH 73  173 426  HOH HOH E . 
K 4 HOH 74  174 63   HOH HOH E . 
K 4 HOH 75  175 458  HOH HOH E . 
K 4 HOH 76  176 740  HOH HOH E . 
K 4 HOH 77  177 804  HOH HOH E . 
K 4 HOH 78  178 47   HOH HOH E . 
K 4 HOH 79  179 893  HOH HOH E . 
K 4 HOH 80  180 725  HOH HOH E . 
K 4 HOH 81  181 234  HOH HOH E . 
K 4 HOH 82  182 712  HOH HOH E . 
K 4 HOH 83  183 376  HOH HOH E . 
K 4 HOH 84  184 202  HOH HOH E . 
K 4 HOH 85  185 671  HOH HOH E . 
K 4 HOH 86  186 421  HOH HOH E . 
K 4 HOH 87  187 814  HOH HOH E . 
K 4 HOH 88  188 605  HOH HOH E . 
K 4 HOH 89  189 395  HOH HOH E . 
K 4 HOH 90  190 129  HOH HOH E . 
K 4 HOH 91  191 59   HOH HOH E . 
K 4 HOH 92  192 272  HOH HOH E . 
K 4 HOH 93  193 448  HOH HOH E . 
K 4 HOH 94  194 215  HOH HOH E . 
K 4 HOH 95  195 428  HOH HOH E . 
K 4 HOH 96  196 952  HOH HOH E . 
K 4 HOH 97  197 552  HOH HOH E . 
K 4 HOH 98  198 888  HOH HOH E . 
K 4 HOH 99  199 746  HOH HOH E . 
K 4 HOH 100 200 759  HOH HOH E . 
K 4 HOH 101 201 966  HOH HOH E . 
K 4 HOH 102 202 954  HOH HOH E . 
K 4 HOH 103 203 1076 HOH HOH E . 
K 4 HOH 104 204 1037 HOH HOH E . 
K 4 HOH 105 205 950  HOH HOH E . 
K 4 HOH 106 206 965  HOH HOH E . 
K 4 HOH 107 207 951  HOH HOH E . 
K 4 HOH 108 208 1021 HOH HOH E . 
K 4 HOH 109 209 706  HOH HOH E . 
K 4 HOH 110 210 585  HOH HOH E . 
K 4 HOH 111 211 407  HOH HOH E . 
K 4 HOH 112 212 921  HOH HOH E . 
K 4 HOH 113 213 484  HOH HOH E . 
K 4 HOH 114 214 680  HOH HOH E . 
K 4 HOH 115 215 802  HOH HOH E . 
K 4 HOH 116 216 662  HOH HOH E . 
K 4 HOH 117 217 570  HOH HOH E . 
K 4 HOH 118 218 616  HOH HOH E . 
K 4 HOH 119 219 1066 HOH HOH E . 
K 4 HOH 120 220 645  HOH HOH E . 
K 4 HOH 121 221 673  HOH HOH E . 
K 4 HOH 122 222 271  HOH HOH E . 
K 4 HOH 123 223 636  HOH HOH E . 
K 4 HOH 124 224 238  HOH HOH E . 
K 4 HOH 125 225 559  HOH HOH E . 
K 4 HOH 126 226 1002 HOH HOH E . 
K 4 HOH 127 227 291  HOH HOH E . 
K 4 HOH 128 228 304  HOH HOH E . 
K 4 HOH 129 229 620  HOH HOH E . 
K 4 HOH 130 230 363  HOH HOH E . 
K 4 HOH 131 231 285  HOH HOH E . 
L 4 HOH 1   101 127  HOH HOH F . 
L 4 HOH 2   102 299  HOH HOH F . 
L 4 HOH 3   103 236  HOH HOH F . 
L 4 HOH 4   104 307  HOH HOH F . 
L 4 HOH 5   105 481  HOH HOH F . 
L 4 HOH 6   106 52   HOH HOH F . 
L 4 HOH 7   107 223  HOH HOH F . 
L 4 HOH 8   108 98   HOH HOH F . 
L 4 HOH 9   109 348  HOH HOH F . 
L 4 HOH 10  110 117  HOH HOH F . 
L 4 HOH 11  111 125  HOH HOH F . 
L 4 HOH 12  112 83   HOH HOH F . 
L 4 HOH 13  113 474  HOH HOH F . 
L 4 HOH 14  114 818  HOH HOH F . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 0 A ARG 108 ? CG  ? A ARG 107 CG  
2  1 Y 0 A ARG 108 ? CD  ? A ARG 107 CD  
3  1 Y 0 A ARG 108 ? NE  ? A ARG 107 NE  
4  1 Y 0 A ARG 108 ? CZ  ? A ARG 107 CZ  
5  1 Y 0 A ARG 108 ? NH1 ? A ARG 107 NH1 
6  1 Y 0 A ARG 108 ? NH2 ? A ARG 107 NH2 
7  1 Y 0 A ARG 181 ? CG  ? A ARG 180 CG  
8  1 Y 0 A ARG 181 ? CD  ? A ARG 180 CD  
9  1 Y 0 A ARG 181 ? NE  ? A ARG 180 NE  
10 1 Y 0 A ARG 181 ? CZ  ? A ARG 180 CZ  
11 1 Y 0 A ARG 181 ? NH1 ? A ARG 180 NH1 
12 1 Y 0 A ARG 181 ? NH2 ? A ARG 180 NH2 
13 1 Y 0 A ASP 196 ? CB  ? A ASP 195 CB  
14 1 Y 0 A ASP 196 ? CG  ? A ASP 195 CG  
15 1 Y 0 A ASP 196 ? OD1 ? A ASP 195 OD1 
16 1 Y 0 A ASP 196 ? OD2 ? A ASP 195 OD2 
17 1 Y 0 A GLU 222 ? CG  ? A GLU 221 CG  
18 1 Y 0 A GLU 222 ? CD  ? A GLU 221 CD  
19 1 Y 0 A GLU 222 ? OE1 ? A GLU 221 OE1 
20 1 Y 0 A GLU 222 ? OE2 ? A GLU 221 OE2 
21 1 Y 0 A GLN 226 ? CG  ? A GLN 225 CG  
22 1 Y 0 A GLN 226 ? CD  ? A GLN 225 CD  
23 1 Y 0 A GLN 226 ? OE1 ? A GLN 225 OE1 
24 1 Y 0 A GLN 226 ? NE2 ? A GLN 225 NE2 
25 1 Y 0 A GLN 255 ? CG  ? A GLN 254 CG  
26 1 Y 0 A GLN 255 ? CD  ? A GLN 254 CD  
27 1 Y 0 A GLN 255 ? OE1 ? A GLN 254 OE1 
28 1 Y 0 A GLN 255 ? NE2 ? A GLN 254 NE2 
29 1 Y 0 A GLU 268 ? CD  ? A GLU 267 CD  
30 1 Y 0 A GLU 268 ? OE1 ? A GLU 267 OE1 
31 1 Y 0 A GLU 268 ? OE2 ? A GLU 267 OE2 
32 1 Y 0 B LYS 48  ? CG  ? B LYS 48  CG  
33 1 Y 0 B LYS 48  ? CD  ? B LYS 48  CD  
34 1 Y 0 B LYS 48  ? CE  ? B LYS 48  CE  
35 1 Y 0 B LYS 48  ? NZ  ? B LYS 48  NZ  
36 1 Y 0 D ARG 62  ? NH1 ? D ARG 61  NH1 
37 1 Y 0 D ARG 62  ? NH2 ? D ARG 61  NH2 
38 1 Y 0 D ASP 196 ? CG  ? D ASP 195 CG  
39 1 Y 0 D ASP 196 ? OD1 ? D ASP 195 OD1 
40 1 Y 0 D ASP 196 ? OD2 ? D ASP 195 OD2 
41 1 Y 0 D GLN 226 ? CD  ? D GLN 225 CD  
42 1 Y 0 D GLN 226 ? OE1 ? D GLN 225 OE1 
43 1 Y 0 D GLN 226 ? NE2 ? D GLN 225 NE2 
44 1 Y 0 E LYS 48  ? CD  ? E LYS 48  CD  
45 1 Y 0 E LYS 48  ? CE  ? E LYS 48  CE  
46 1 Y 0 E LYS 48  ? NZ  ? E LYS 48  NZ  
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX  ? ? ? 1.20.1_4487 1 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX  ? ? ? 1.20.1_4487 2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? MOSFLM  ? ? ? .           3 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .           4 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .           5 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9L4A 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     79.520 
_cell.length_a_esd                 ? 
_cell.length_b                     96.400 
_cell.length_b_esd                 ? 
_cell.length_c                     121.100 
_cell.length_c_esd                 ? 
_cell.volume                       928319.661 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9L4A 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            'P 2ac 2ab' 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9L4A 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.61 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          52.83 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.2M Sodium formate 0.1M Bis-Tris propane pH8.5 20% w/v PEG3,350' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            277.15 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     95 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     CCD 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'ADSC QUANTUM 315r' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-05-01 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.9785 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRF BEAMLINE BL17UM' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.9785 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL17UM 
_diffrn_source.pdbx_synchrotron_site       SSRF 
# 
_reflns.B_iso_Wilson_estimate                          17.31 
_reflns.entry_id                                       9L4A 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.9 
_reflns.d_resolution_low                               48.20 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     73658 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.6 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                11.2 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          17.0 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               0.99 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.106 
_reflns.pdbx_Rpim_I_all                                0.031 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.998 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.097 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.90 
_reflns_shell.d_res_low                                     1.94 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             4455 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               10.9 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               0.554 
_reflns_shell.pdbx_Rpim_I_all                               0.232 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.915 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          98.7 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.502 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               21.13 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9L4A 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.90 
_refine.ls_d_res_low                             41.22 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     73572 
_refine.ls_number_reflns_R_free                  2000 
_refine.ls_number_reflns_R_work                  71572 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.47 
_refine.ls_percent_reflns_R_free                 2.72 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1655 
_refine.ls_R_factor_R_free                       0.2073 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1643 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.34 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 19.8156 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.1970 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.90 
_refine_hist.d_res_low                        41.22 
_refine_hist.number_atoms_solvent             1009 
_refine_hist.number_atoms_total               7273 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        6264 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         0 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0195  ? 6459 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.4872  ? 8771 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.1042  ? 877  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0157  ? 1165 ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 14.8338 ? 2391 ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.90 1.95  . . 140 5020 98.68 . . . . 0.2038 . . . . . . . . . . . 0.2869 
'X-RAY DIFFRACTION' 1.95 2.00  . . 140 5008 98.73 . . . . 0.1754 . . . . . . . . . . . 0.2567 
'X-RAY DIFFRACTION' 2.00 2.06  . . 139 5001 98.92 . . . . 0.1684 . . . . . . . . . . . 0.2210 
'X-RAY DIFFRACTION' 2.06 2.13  . . 141 5041 99.04 . . . . 0.1720 . . . . . . . . . . . 0.2032 
'X-RAY DIFFRACTION' 2.13 2.20  . . 142 5059 99.10 . . . . 0.1685 . . . . . . . . . . . 0.2516 
'X-RAY DIFFRACTION' 2.20 2.29  . . 142 5074 99.77 . . . . 0.1660 . . . . . . . . . . . 0.2164 
'X-RAY DIFFRACTION' 2.29 2.39  . . 142 5086 99.94 . . . . 0.1694 . . . . . . . . . . . 0.2561 
'X-RAY DIFFRACTION' 2.39 2.52  . . 143 5113 99.94 . . . . 0.1705 . . . . . . . . . . . 0.2136 
'X-RAY DIFFRACTION' 2.52 2.68  . . 143 5133 99.74 . . . . 0.1727 . . . . . . . . . . . 0.2343 
'X-RAY DIFFRACTION' 2.68 2.88  . . 143 5079 99.62 . . . . 0.1722 . . . . . . . . . . . 0.1773 
'X-RAY DIFFRACTION' 2.88 3.17  . . 144 5169 99.98 . . . . 0.1664 . . . . . . . . . . . 0.2196 
'X-RAY DIFFRACTION' 3.17 3.63  . . 144 5176 99.98 . . . . 0.1576 . . . . . . . . . . . 0.1838 
'X-RAY DIFFRACTION' 3.63 4.58  . . 145 5201 99.53 . . . . 0.1397 . . . . . . . . . . . 0.1708 
'X-RAY DIFFRACTION' 4.58 41.22 . . 152 5412 99.55 . . . . 0.1649 . . . . . . . . . . . 0.1918 
# 
_struct.entry_id                     9L4A 
_struct.title                        'Crystal structure of HLA-C*12:02-MY9' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9L4A 
_struct_keywords.text            'HLA-C*12:02, complex, IMMUNE SYSTEM' 
_struct_keywords.pdbx_keywords   'IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 1 ? 
E N N 2 ? 
F N N 3 ? 
G N N 4 ? 
H N N 4 ? 
I N N 4 ? 
J N N 4 ? 
K N N 4 ? 
L N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP S5DHS4_HUMAN S5DHS4 ? 1 
;SHSMRYFYTAVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRGEPRAPWVEQEGPEYWDRETQKYKRQAQADRVSLRNL
RGYYNQSEAGSHTLQRMYGCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREAEQWRAYLE
GTCVEWLRRYLENGKETLQRAEHPKTHVTHHPVSDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTF
QKWAAVVVPSGEEQRYTCHVQHEGLPEPLTLRW
;
1  
2 UNP B2MG_HUMAN   P61769 ? 2 
;IQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLLKNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYAC
RVNHVTLSQPKIVKWDRDM
;
21 
3 PDB 9L4A         9L4A   ? 3 ? 1  
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9L4A A 1 ? 273 ? S5DHS4 1  ? 273 ? 2 274 
2 2 9L4A B 1 ? 99  ? P61769 21 ? 119 ? 1 99  
3 3 9L4A C 1 ? 9   ? 9L4A   1  ? 9   ? 1 9   
4 1 9L4A D 1 ? 273 ? S5DHS4 1  ? 273 ? 2 274 
5 2 9L4A E 1 ? 99  ? P61769 21 ? 119 ? 1 99  
6 3 9L4A F 1 ? 9   ? 9L4A   1  ? 9   ? 1 9   
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
2 9L4A GLY B 58 ? UNP P61769 LYS 78 conflict 58 1 
5 9L4A GLY E 58 ? UNP P61769 LYS 78 conflict 58 2 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_and_software_defined_assembly PISA trimeric 3 
2 author_and_software_defined_assembly PISA trimeric 3 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 4380  ? 
1 MORE         -17   ? 
1 'SSA (A^2)'  18950 ? 
2 'ABSA (A^2)' 4460  ? 
2 MORE         -17   ? 
2 'SSA (A^2)'  18890 ? 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,B,C,G,H,I 
2 1 D,E,F,J,K,L 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ALA A 48  ? GLN A 53  ? ALA A 49  GLN A 54  1 ? 6  
HELX_P HELX_P2  AA2 GLY A 55  ? ASN A 85  ? GLY A 56  ASN A 86  1 ? 31 
HELX_P HELX_P3  AA3 ASP A 136 ? ALA A 149 ? ASP A 137 ALA A 150 1 ? 14 
HELX_P HELX_P4  AA4 ARG A 150 ? GLY A 161 ? ARG A 151 GLY A 162 1 ? 12 
HELX_P HELX_P5  AA5 GLY A 161 ? GLY A 174 ? GLY A 162 GLY A 175 1 ? 14 
HELX_P HELX_P6  AA6 GLY A 174 ? GLN A 179 ? GLY A 175 GLN A 180 1 ? 6  
HELX_P HELX_P7  AA7 GLU A 252 ? GLN A 254 ? GLU A 253 GLN A 255 5 ? 3  
HELX_P HELX_P8  AA8 ALA D 48  ? GLU D 52  ? ALA D 49  GLU D 53  5 ? 5  
HELX_P HELX_P9  AA9 GLY D 55  ? TYR D 84  ? GLY D 56  TYR D 85  1 ? 30 
HELX_P HELX_P10 AB1 ASP D 136 ? ALA D 149 ? ASP D 137 ALA D 150 1 ? 14 
HELX_P HELX_P11 AB2 ARG D 150 ? GLY D 161 ? ARG D 151 GLY D 162 1 ? 12 
HELX_P HELX_P12 AB3 GLY D 161 ? GLY D 174 ? GLY D 162 GLY D 175 1 ? 14 
HELX_P HELX_P13 AB4 GLY D 174 ? GLN D 179 ? GLY D 175 GLN D 180 1 ? 6  
HELX_P HELX_P14 AB5 THR D 224 ? THR D 227 ? THR D 225 THR D 228 5 ? 4  
HELX_P HELX_P15 AB6 GLU D 252 ? GLN D 254 ? GLU D 253 GLN D 255 5 ? 3  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 100 SG ? ? ? 1_555 A CYS 163 SG ? ? A CYS 101 A CYS 164 1_555 ? ? ? ? ? ? ? 2.088 ? ? 
disulf2 disulf ? ? A CYS 202 SG ? ? ? 1_555 A CYS 258 SG ? ? A CYS 203 A CYS 259 1_555 ? ? ? ? ? ? ? 2.049 ? ? 
disulf3 disulf ? ? B CYS 25  SG ? ? ? 1_555 B CYS 80  SG ? ? B CYS 25  B CYS 80  1_555 ? ? ? ? ? ? ? 2.080 ? ? 
disulf4 disulf ? ? D CYS 100 SG ? ? ? 1_555 D CYS 163 SG ? ? D CYS 101 D CYS 164 1_555 ? ? ? ? ? ? ? 2.138 ? ? 
disulf5 disulf ? ? D CYS 202 SG ? ? ? 1_555 D CYS 258 SG ? ? D CYS 203 D CYS 259 1_555 ? ? ? ? ? ? ? 2.078 ? ? 
disulf6 disulf ? ? E CYS 25  SG ? ? ? 1_555 E CYS 80  SG ? ? E CYS 25  E CYS 80  1_555 ? ? ? ? ? ? ? 2.128 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 100 ? CYS A 163 ? CYS A 101 ? 1_555 CYS A 164 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS A 202 ? CYS A 258 ? CYS A 203 ? 1_555 CYS A 259 ? 1_555 SG SG . . . None 'Disulfide bridge' 
3 CYS B 25  ? CYS B 80  ? CYS B 25  ? 1_555 CYS B 80  ? 1_555 SG SG . . . None 'Disulfide bridge' 
4 CYS D 100 ? CYS D 163 ? CYS D 101 ? 1_555 CYS D 164 ? 1_555 SG SG . . . None 'Disulfide bridge' 
5 CYS D 202 ? CYS D 258 ? CYS D 203 ? 1_555 CYS D 259 ? 1_555 SG SG . . . None 'Disulfide bridge' 
6 CYS E 25  ? CYS E 80  ? CYS E 25  ? 1_555 CYS E 80  ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 TYR 208 A . ? TYR 209 A PRO 209 A ? PRO 210 A 1 7.56  
2 HIS 31  B . ? HIS 31  B PRO 32  B ? PRO 32  B 1 6.68  
3 TYR 208 D . ? TYR 209 D PRO 209 D ? PRO 210 D 1 -3.77 
4 HIS 31  E . ? HIS 31  E PRO 32  E ? PRO 32  E 1 0.28  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 8 ? 
AA2 ? 4 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 4 ? 
AA7 ? 4 ? 
AA8 ? 8 ? 
AA9 ? 4 ? 
AB1 ? 4 ? 
AB2 ? 4 ? 
AB3 ? 4 ? 
AB4 ? 4 ? 
AB5 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA1 5 6 ? anti-parallel 
AA1 6 7 ? anti-parallel 
AA1 7 8 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA8 4 5 ? anti-parallel 
AA8 5 6 ? anti-parallel 
AA8 6 7 ? anti-parallel 
AA8 7 8 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLU A 45  ? PRO A 46  ? GLU A 46  PRO A 47  
AA1 2 THR A 30  ? ASP A 36  ? THR A 31  ASP A 37  
AA1 3 ARG A 20  ? VAL A 27  ? ARG A 21  VAL A 28  
AA1 4 HIS A 2   ? VAL A 11  ? HIS A 3   VAL A 12  
AA1 5 THR A 93  ? LEU A 102 ? THR A 94  LEU A 103 
AA1 6 LEU A 108 ? TYR A 117 ? LEU A 109 TYR A 118 
AA1 7 LYS A 120 ? LEU A 125 ? LYS A 121 LEU A 126 
AA1 8 TRP A 132 ? ALA A 134 ? TRP A 133 ALA A 135 
AA2 1 LYS A 185 ? PRO A 192 ? LYS A 186 PRO A 193 
AA2 2 GLU A 197 ? PHE A 207 ? GLU A 198 PHE A 208 
AA2 3 PHE A 240 ? PRO A 249 ? PHE A 241 PRO A 250 
AA2 4 THR A 227 ? LEU A 229 ? THR A 228 LEU A 230 
AA3 1 LYS A 185 ? PRO A 192 ? LYS A 186 PRO A 193 
AA3 2 GLU A 197 ? PHE A 207 ? GLU A 198 PHE A 208 
AA3 3 PHE A 240 ? PRO A 249 ? PHE A 241 PRO A 250 
AA3 4 ARG A 233 ? PRO A 234 ? ARG A 234 PRO A 235 
AA4 1 GLU A 221 ? ASP A 222 ? GLU A 222 ASP A 223 
AA4 2 THR A 213 ? ARG A 218 ? THR A 214 ARG A 219 
AA4 3 TYR A 256 ? GLN A 261 ? TYR A 257 GLN A 262 
AA4 4 LEU A 269 ? LEU A 271 ? LEU A 270 LEU A 272 
AA5 1 LYS B 6   ? SER B 11  ? LYS B 6   SER B 11  
AA5 2 ASN B 21  ? PHE B 30  ? ASN B 21  PHE B 30  
AA5 3 PHE B 62  ? PHE B 70  ? PHE B 62  PHE B 70  
AA5 4 GLU B 50  ? HIS B 51  ? GLU B 50  HIS B 51  
AA6 1 LYS B 6   ? SER B 11  ? LYS B 6   SER B 11  
AA6 2 ASN B 21  ? PHE B 30  ? ASN B 21  PHE B 30  
AA6 3 PHE B 62  ? PHE B 70  ? PHE B 62  PHE B 70  
AA6 4 SER B 55  ? PHE B 56  ? SER B 55  PHE B 56  
AA7 1 GLU B 44  ? ARG B 45  ? GLU B 44  ARG B 45  
AA7 2 GLU B 36  ? LYS B 41  ? GLU B 36  LYS B 41  
AA7 3 TYR B 78  ? ASN B 83  ? TYR B 78  ASN B 83  
AA7 4 LYS B 91  ? LYS B 94  ? LYS B 91  LYS B 94  
AA8 1 GLU D 45  ? PRO D 46  ? GLU D 46  PRO D 47  
AA8 2 THR D 30  ? ASP D 36  ? THR D 31  ASP D 37  
AA8 3 ARG D 20  ? VAL D 27  ? ARG D 21  VAL D 28  
AA8 4 SER D 3   ? VAL D 11  ? SER D 4   VAL D 12  
AA8 5 THR D 93  ? LEU D 102 ? THR D 94  LEU D 103 
AA8 6 LEU D 108 ? TYR D 117 ? LEU D 109 TYR D 118 
AA8 7 LYS D 120 ? LEU D 125 ? LYS D 121 LEU D 126 
AA8 8 TRP D 132 ? ALA D 134 ? TRP D 133 ALA D 135 
AA9 1 LYS D 185 ? PRO D 192 ? LYS D 186 PRO D 193 
AA9 2 GLU D 197 ? PHE D 207 ? GLU D 198 PHE D 208 
AA9 3 PHE D 240 ? PRO D 249 ? PHE D 241 PRO D 250 
AA9 4 GLU D 228 ? LEU D 229 ? GLU D 229 LEU D 230 
AB1 1 LYS D 185 ? PRO D 192 ? LYS D 186 PRO D 193 
AB1 2 GLU D 197 ? PHE D 207 ? GLU D 198 PHE D 208 
AB1 3 PHE D 240 ? PRO D 249 ? PHE D 241 PRO D 250 
AB1 4 ARG D 233 ? PRO D 234 ? ARG D 234 PRO D 235 
AB2 1 GLU D 221 ? ASP D 222 ? GLU D 222 ASP D 223 
AB2 2 THR D 213 ? ARG D 218 ? THR D 214 ARG D 219 
AB2 3 TYR D 256 ? GLN D 261 ? TYR D 257 GLN D 262 
AB2 4 LEU D 269 ? LEU D 271 ? LEU D 270 LEU D 272 
AB3 1 LYS E 6   ? SER E 11  ? LYS E 6   SER E 11  
AB3 2 ASN E 21  ? PHE E 30  ? ASN E 21  PHE E 30  
AB3 3 PHE E 62  ? PHE E 70  ? PHE E 62  PHE E 70  
AB3 4 GLU E 50  ? HIS E 51  ? GLU E 50  HIS E 51  
AB4 1 LYS E 6   ? SER E 11  ? LYS E 6   SER E 11  
AB4 2 ASN E 21  ? PHE E 30  ? ASN E 21  PHE E 30  
AB4 3 PHE E 62  ? PHE E 70  ? PHE E 62  PHE E 70  
AB4 4 SER E 55  ? PHE E 56  ? SER E 55  PHE E 56  
AB5 1 GLU E 44  ? ARG E 45  ? GLU E 44  ARG E 45  
AB5 2 GLU E 36  ? LYS E 41  ? GLU E 36  LYS E 41  
AB5 3 TYR E 78  ? ASN E 83  ? TYR E 78  ASN E 83  
AB5 4 LYS E 91  ? LYS E 94  ? LYS E 91  LYS E 94  
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O GLU A 45  ? O GLU A 46  N ARG A 34  ? N ARG A 35  
AA1 2 3 O PHE A 32  ? O PHE A 33  N GLY A 25  ? N GLY A 26  
AA1 3 4 O ILE A 22  ? O ILE A 23  N THR A 9   ? N THR A 10  
AA1 4 5 N TYR A 6   ? N TYR A 7   O TYR A 98  ? O TYR A 99  
AA1 5 6 N ASP A 101 ? N ASP A 102 O LEU A 109 ? O LEU A 110 
AA1 6 7 N SER A 115 ? N SER A 116 O TYR A 122 ? O TYR A 123 
AA1 7 8 N ALA A 124 ? N ALA A 125 O THR A 133 ? O THR A 134 
AA2 1 2 N HIS A 187 ? N HIS A 188 O TRP A 203 ? O TRP A 204 
AA2 2 3 N CYS A 202 ? N CYS A 203 O ALA A 244 ? O ALA A 245 
AA2 3 4 O ALA A 245 ? O ALA A 246 N GLU A 228 ? N GLU A 229 
AA3 1 2 N HIS A 187 ? N HIS A 188 O TRP A 203 ? O TRP A 204 
AA3 2 3 N CYS A 202 ? N CYS A 203 O ALA A 244 ? O ALA A 245 
AA3 3 4 O GLN A 241 ? O GLN A 242 N ARG A 233 ? N ARG A 234 
AA4 1 2 O GLU A 221 ? O GLU A 222 N ARG A 218 ? N ARG A 219 
AA4 2 3 N THR A 215 ? N THR A 216 O HIS A 259 ? O HIS A 260 
AA4 3 4 N CYS A 258 ? N CYS A 259 O LEU A 271 ? O LEU A 272 
AA5 1 2 N TYR B 10  ? N TYR B 10  O ASN B 24  ? O ASN B 24  
AA5 2 3 N PHE B 30  ? N PHE B 30  O PHE B 62  ? O PHE B 62  
AA5 3 4 O TYR B 67  ? O TYR B 67  N GLU B 50  ? N GLU B 50  
AA6 1 2 N TYR B 10  ? N TYR B 10  O ASN B 24  ? O ASN B 24  
AA6 2 3 N PHE B 30  ? N PHE B 30  O PHE B 62  ? O PHE B 62  
AA6 3 4 O TYR B 63  ? O TYR B 63  N SER B 55  ? N SER B 55  
AA7 1 2 O GLU B 44  ? O GLU B 44  N LYS B 41  ? N LYS B 41  
AA7 2 3 N GLU B 36  ? N GLU B 36  O ASN B 83  ? O ASN B 83  
AA7 3 4 N VAL B 82  ? N VAL B 82  O LYS B 91  ? O LYS B 91  
AA8 1 2 O GLU D 45  ? O GLU D 46  N ARG D 34  ? N ARG D 35  
AA8 2 3 O PHE D 32  ? O PHE D 33  N GLY D 25  ? N GLY D 26  
AA8 3 4 O TYR D 26  ? O TYR D 27  N ARG D 5   ? N ARG D 6   
AA8 4 5 N TYR D 8   ? N TYR D 9   O ARG D 96  ? O ARG D 97  
AA8 5 6 N ASP D 101 ? N ASP D 102 O LEU D 109 ? O LEU D 110 
AA8 6 7 N ASP D 113 ? N ASP D 114 O LEU D 125 ? O LEU D 126 
AA8 7 8 N ALA D 124 ? N ALA D 125 O THR D 133 ? O THR D 134 
AA9 1 2 N HIS D 187 ? N HIS D 188 O TRP D 203 ? O TRP D 204 
AA9 2 3 N ALA D 198 ? N ALA D 199 O VAL D 248 ? O VAL D 249 
AA9 3 4 O ALA D 245 ? O ALA D 246 N GLU D 228 ? N GLU D 229 
AB1 1 2 N HIS D 187 ? N HIS D 188 O TRP D 203 ? O TRP D 204 
AB1 2 3 N ALA D 198 ? N ALA D 199 O VAL D 248 ? O VAL D 249 
AB1 3 4 O GLN D 241 ? O GLN D 242 N ARG D 233 ? N ARG D 234 
AB2 1 2 O GLU D 221 ? O GLU D 222 N ARG D 218 ? N ARG D 219 
AB2 2 3 N THR D 215 ? N THR D 216 O HIS D 259 ? O HIS D 260 
AB2 3 4 N CYS D 258 ? N CYS D 259 O LEU D 271 ? O LEU D 272 
AB3 1 2 N TYR E 10  ? N TYR E 10  O ASN E 24  ? O ASN E 24  
AB3 2 3 N LEU E 23  ? N LEU E 23  O THR E 68  ? O THR E 68  
AB3 3 4 O TYR E 67  ? O TYR E 67  N GLU E 50  ? N GLU E 50  
AB4 1 2 N TYR E 10  ? N TYR E 10  O ASN E 24  ? O ASN E 24  
AB4 2 3 N LEU E 23  ? N LEU E 23  O THR E 68  ? O THR E 68  
AB4 3 4 O TYR E 63  ? O TYR E 63  N SER E 55  ? N SER E 55  
AB5 1 2 O GLU E 44  ? O GLU E 44  N LYS E 41  ? N LYS E 41  
AB5 2 3 N LEU E 40  ? N LEU E 40  O ALA E 79  ? O ALA E 79  
AB5 3 4 N VAL E 82  ? N VAL E 82  O LYS E 91  ? O LYS E 91  
# 
_pdbx_entry_details.entry_id                   9L4A 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 OE2 A GLU 232 ? ? O A HOH 301 ? ? 1.42 
2 1 OE1 A GLU 232 ? ? O A HOH 302 ? ? 1.51 
3 1 O   E HOH 122 ? ? O E HOH 177 ? ? 2.15 
4 1 O   B HOH 187 ? ? O B HOH 234 ? ? 2.19 
5 1 O   B HOH 180 ? ? O B HOH 222 ? ? 2.19 
# 
loop_
_pdbx_validate_rmsd_bond.id 
_pdbx_validate_rmsd_bond.PDB_model_num 
_pdbx_validate_rmsd_bond.auth_atom_id_1 
_pdbx_validate_rmsd_bond.auth_asym_id_1 
_pdbx_validate_rmsd_bond.auth_comp_id_1 
_pdbx_validate_rmsd_bond.auth_seq_id_1 
_pdbx_validate_rmsd_bond.PDB_ins_code_1 
_pdbx_validate_rmsd_bond.label_alt_id_1 
_pdbx_validate_rmsd_bond.auth_atom_id_2 
_pdbx_validate_rmsd_bond.auth_asym_id_2 
_pdbx_validate_rmsd_bond.auth_comp_id_2 
_pdbx_validate_rmsd_bond.auth_seq_id_2 
_pdbx_validate_rmsd_bond.PDB_ins_code_2 
_pdbx_validate_rmsd_bond.label_alt_id_2 
_pdbx_validate_rmsd_bond.bond_value 
_pdbx_validate_rmsd_bond.bond_target_value 
_pdbx_validate_rmsd_bond.bond_deviation 
_pdbx_validate_rmsd_bond.bond_standard_deviation 
_pdbx_validate_rmsd_bond.linker_flag 
1 1 CB A GLU 232 ? ? CG  A GLU 232 ? ? 1.305 1.517 -0.212 0.019 N 
2 1 CD D GLU 55  ? ? OE2 D GLU 55  ? ? 1.160 1.252 -0.092 0.011 N 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 OE1 A GLU 232 ? ? CD A GLU 232 ? ? OE2 A GLU 232 ? ? 111.22 123.30 -12.08 1.20 N 
2 1 CG  F MET 1   ? ? SD F MET 1   ? ? CE  F MET 1   ? ? 87.98  100.20 -12.22 1.60 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 ASP A 29 ? ? 47.91  -124.73 
2 1 LYS B 48 ? ? -96.34 48.89   
3 1 TRP B 60 ? ? 76.83  -6.61   
4 1 ASP D 29 ? ? 52.83  -126.37 
5 1 PRO E 32 ? ? -69.74 -179.53 
6 1 TRP E 60 ? ? 79.56  -1.80   
7 1 LEU F 5  ? ? -39.95 135.03  
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z           
2 x+1/2,-y+1/2,-z 
3 -x,y+1/2,-z+1/2 
4 -x+1/2,-y,z+1/2 
# 
loop_
_pdbx_distant_solvent_atoms.id 
_pdbx_distant_solvent_atoms.PDB_model_num 
_pdbx_distant_solvent_atoms.auth_atom_id 
_pdbx_distant_solvent_atoms.label_alt_id 
_pdbx_distant_solvent_atoms.auth_asym_id 
_pdbx_distant_solvent_atoms.auth_comp_id 
_pdbx_distant_solvent_atoms.auth_seq_id 
_pdbx_distant_solvent_atoms.PDB_ins_code 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance 
1 1 O ? A HOH 611 ? 5.83 . 
2 1 O ? A HOH 612 ? 6.05 . 
3 1 O ? C HOH 121 ? 6.45 . 
4 1 O ? D HOH 672 ? 5.87 . 
5 1 O ? D HOH 673 ? 6.10 . 
6 1 O ? D HOH 674 ? 6.14 . 
7 1 O ? D HOH 675 ? 6.74 . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 B ILE 1 ? B ILE 1 
2 1 Y 1 D SER 2 ? D SER 1 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
HOH O    O N N 158 
HOH H1   H N N 159 
HOH H2   H N N 160 
ILE N    N N N 161 
ILE CA   C N S 162 
ILE C    C N N 163 
ILE O    O N N 164 
ILE CB   C N S 165 
ILE CG1  C N N 166 
ILE CG2  C N N 167 
ILE CD1  C N N 168 
ILE OXT  O N N 169 
ILE H    H N N 170 
ILE H2   H N N 171 
ILE HA   H N N 172 
ILE HB   H N N 173 
ILE HG12 H N N 174 
ILE HG13 H N N 175 
ILE HG21 H N N 176 
ILE HG22 H N N 177 
ILE HG23 H N N 178 
ILE HD11 H N N 179 
ILE HD12 H N N 180 
ILE HD13 H N N 181 
ILE HXT  H N N 182 
LEU N    N N N 183 
LEU CA   C N S 184 
LEU C    C N N 185 
LEU O    O N N 186 
LEU CB   C N N 187 
LEU CG   C N N 188 
LEU CD1  C N N 189 
LEU CD2  C N N 190 
LEU OXT  O N N 191 
LEU H    H N N 192 
LEU H2   H N N 193 
LEU HA   H N N 194 
LEU HB2  H N N 195 
LEU HB3  H N N 196 
LEU HG   H N N 197 
LEU HD11 H N N 198 
LEU HD12 H N N 199 
LEU HD13 H N N 200 
LEU HD21 H N N 201 
LEU HD22 H N N 202 
LEU HD23 H N N 203 
LEU HXT  H N N 204 
LYS N    N N N 205 
LYS CA   C N S 206 
LYS C    C N N 207 
LYS O    O N N 208 
LYS CB   C N N 209 
LYS CG   C N N 210 
LYS CD   C N N 211 
LYS CE   C N N 212 
LYS NZ   N N N 213 
LYS OXT  O N N 214 
LYS H    H N N 215 
LYS H2   H N N 216 
LYS HA   H N N 217 
LYS HB2  H N N 218 
LYS HB3  H N N 219 
LYS HG2  H N N 220 
LYS HG3  H N N 221 
LYS HD2  H N N 222 
LYS HD3  H N N 223 
LYS HE2  H N N 224 
LYS HE3  H N N 225 
LYS HZ1  H N N 226 
LYS HZ2  H N N 227 
LYS HZ3  H N N 228 
LYS HXT  H N N 229 
MET N    N N N 230 
MET CA   C N S 231 
MET C    C N N 232 
MET O    O N N 233 
MET CB   C N N 234 
MET CG   C N N 235 
MET SD   S N N 236 
MET CE   C N N 237 
MET OXT  O N N 238 
MET H    H N N 239 
MET H2   H N N 240 
MET HA   H N N 241 
MET HB2  H N N 242 
MET HB3  H N N 243 
MET HG2  H N N 244 
MET HG3  H N N 245 
MET HE1  H N N 246 
MET HE2  H N N 247 
MET HE3  H N N 248 
MET HXT  H N N 249 
PHE N    N N N 250 
PHE CA   C N S 251 
PHE C    C N N 252 
PHE O    O N N 253 
PHE CB   C N N 254 
PHE CG   C Y N 255 
PHE CD1  C Y N 256 
PHE CD2  C Y N 257 
PHE CE1  C Y N 258 
PHE CE2  C Y N 259 
PHE CZ   C Y N 260 
PHE OXT  O N N 261 
PHE H    H N N 262 
PHE H2   H N N 263 
PHE HA   H N N 264 
PHE HB2  H N N 265 
PHE HB3  H N N 266 
PHE HD1  H N N 267 
PHE HD2  H N N 268 
PHE HE1  H N N 269 
PHE HE2  H N N 270 
PHE HZ   H N N 271 
PHE HXT  H N N 272 
PRO N    N N N 273 
PRO CA   C N S 274 
PRO C    C N N 275 
PRO O    O N N 276 
PRO CB   C N N 277 
PRO CG   C N N 278 
PRO CD   C N N 279 
PRO OXT  O N N 280 
PRO H    H N N 281 
PRO HA   H N N 282 
PRO HB2  H N N 283 
PRO HB3  H N N 284 
PRO HG2  H N N 285 
PRO HG3  H N N 286 
PRO HD2  H N N 287 
PRO HD3  H N N 288 
PRO HXT  H N N 289 
SER N    N N N 290 
SER CA   C N S 291 
SER C    C N N 292 
SER O    O N N 293 
SER CB   C N N 294 
SER OG   O N N 295 
SER OXT  O N N 296 
SER H    H N N 297 
SER H2   H N N 298 
SER HA   H N N 299 
SER HB2  H N N 300 
SER HB3  H N N 301 
SER HG   H N N 302 
SER HXT  H N N 303 
THR N    N N N 304 
THR CA   C N S 305 
THR C    C N N 306 
THR O    O N N 307 
THR CB   C N R 308 
THR OG1  O N N 309 
THR CG2  C N N 310 
THR OXT  O N N 311 
THR H    H N N 312 
THR H2   H N N 313 
THR HA   H N N 314 
THR HB   H N N 315 
THR HG1  H N N 316 
THR HG21 H N N 317 
THR HG22 H N N 318 
THR HG23 H N N 319 
THR HXT  H N N 320 
TRP N    N N N 321 
TRP CA   C N S 322 
TRP C    C N N 323 
TRP O    O N N 324 
TRP CB   C N N 325 
TRP CG   C Y N 326 
TRP CD1  C Y N 327 
TRP CD2  C Y N 328 
TRP NE1  N Y N 329 
TRP CE2  C Y N 330 
TRP CE3  C Y N 331 
TRP CZ2  C Y N 332 
TRP CZ3  C Y N 333 
TRP CH2  C Y N 334 
TRP OXT  O N N 335 
TRP H    H N N 336 
TRP H2   H N N 337 
TRP HA   H N N 338 
TRP HB2  H N N 339 
TRP HB3  H N N 340 
TRP HD1  H N N 341 
TRP HE1  H N N 342 
TRP HE3  H N N 343 
TRP HZ2  H N N 344 
TRP HZ3  H N N 345 
TRP HH2  H N N 346 
TRP HXT  H N N 347 
TYR N    N N N 348 
TYR CA   C N S 349 
TYR C    C N N 350 
TYR O    O N N 351 
TYR CB   C N N 352 
TYR CG   C Y N 353 
TYR CD1  C Y N 354 
TYR CD2  C Y N 355 
TYR CE1  C Y N 356 
TYR CE2  C Y N 357 
TYR CZ   C Y N 358 
TYR OH   O N N 359 
TYR OXT  O N N 360 
TYR H    H N N 361 
TYR H2   H N N 362 
TYR HA   H N N 363 
TYR HB2  H N N 364 
TYR HB3  H N N 365 
TYR HD1  H N N 366 
TYR HD2  H N N 367 
TYR HE1  H N N 368 
TYR HE2  H N N 369 
TYR HH   H N N 370 
TYR HXT  H N N 371 
VAL N    N N N 372 
VAL CA   C N S 373 
VAL C    C N N 374 
VAL O    O N N 375 
VAL CB   C N N 376 
VAL CG1  C N N 377 
VAL CG2  C N N 378 
VAL OXT  O N N 379 
VAL H    H N N 380 
VAL H2   H N N 381 
VAL HA   H N N 382 
VAL HB   H N N 383 
VAL HG11 H N N 384 
VAL HG12 H N N 385 
VAL HG13 H N N 386 
VAL HG21 H N N 387 
VAL HG22 H N N 388 
VAL HG23 H N N 389 
VAL HXT  H N N 390 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
PHE N   CA   sing N N 237 
PHE N   H    sing N N 238 
PHE N   H2   sing N N 239 
PHE CA  C    sing N N 240 
PHE CA  CB   sing N N 241 
PHE CA  HA   sing N N 242 
PHE C   O    doub N N 243 
PHE C   OXT  sing N N 244 
PHE CB  CG   sing N N 245 
PHE CB  HB2  sing N N 246 
PHE CB  HB3  sing N N 247 
PHE CG  CD1  doub Y N 248 
PHE CG  CD2  sing Y N 249 
PHE CD1 CE1  sing Y N 250 
PHE CD1 HD1  sing N N 251 
PHE CD2 CE2  doub Y N 252 
PHE CD2 HD2  sing N N 253 
PHE CE1 CZ   doub Y N 254 
PHE CE1 HE1  sing N N 255 
PHE CE2 CZ   sing Y N 256 
PHE CE2 HE2  sing N N 257 
PHE CZ  HZ   sing N N 258 
PHE OXT HXT  sing N N 259 
PRO N   CA   sing N N 260 
PRO N   CD   sing N N 261 
PRO N   H    sing N N 262 
PRO CA  C    sing N N 263 
PRO CA  CB   sing N N 264 
PRO CA  HA   sing N N 265 
PRO C   O    doub N N 266 
PRO C   OXT  sing N N 267 
PRO CB  CG   sing N N 268 
PRO CB  HB2  sing N N 269 
PRO CB  HB3  sing N N 270 
PRO CG  CD   sing N N 271 
PRO CG  HG2  sing N N 272 
PRO CG  HG3  sing N N 273 
PRO CD  HD2  sing N N 274 
PRO CD  HD3  sing N N 275 
PRO OXT HXT  sing N N 276 
SER N   CA   sing N N 277 
SER N   H    sing N N 278 
SER N   H2   sing N N 279 
SER CA  C    sing N N 280 
SER CA  CB   sing N N 281 
SER CA  HA   sing N N 282 
SER C   O    doub N N 283 
SER C   OXT  sing N N 284 
SER CB  OG   sing N N 285 
SER CB  HB2  sing N N 286 
SER CB  HB3  sing N N 287 
SER OG  HG   sing N N 288 
SER OXT HXT  sing N N 289 
THR N   CA   sing N N 290 
THR N   H    sing N N 291 
THR N   H2   sing N N 292 
THR CA  C    sing N N 293 
THR CA  CB   sing N N 294 
THR CA  HA   sing N N 295 
THR C   O    doub N N 296 
THR C   OXT  sing N N 297 
THR CB  OG1  sing N N 298 
THR CB  CG2  sing N N 299 
THR CB  HB   sing N N 300 
THR OG1 HG1  sing N N 301 
THR CG2 HG21 sing N N 302 
THR CG2 HG22 sing N N 303 
THR CG2 HG23 sing N N 304 
THR OXT HXT  sing N N 305 
TRP N   CA   sing N N 306 
TRP N   H    sing N N 307 
TRP N   H2   sing N N 308 
TRP CA  C    sing N N 309 
TRP CA  CB   sing N N 310 
TRP CA  HA   sing N N 311 
TRP C   O    doub N N 312 
TRP C   OXT  sing N N 313 
TRP CB  CG   sing N N 314 
TRP CB  HB2  sing N N 315 
TRP CB  HB3  sing N N 316 
TRP CG  CD1  doub Y N 317 
TRP CG  CD2  sing Y N 318 
TRP CD1 NE1  sing Y N 319 
TRP CD1 HD1  sing N N 320 
TRP CD2 CE2  doub Y N 321 
TRP CD2 CE3  sing Y N 322 
TRP NE1 CE2  sing Y N 323 
TRP NE1 HE1  sing N N 324 
TRP CE2 CZ2  sing Y N 325 
TRP CE3 CZ3  doub Y N 326 
TRP CE3 HE3  sing N N 327 
TRP CZ2 CH2  doub Y N 328 
TRP CZ2 HZ2  sing N N 329 
TRP CZ3 CH2  sing Y N 330 
TRP CZ3 HZ3  sing N N 331 
TRP CH2 HH2  sing N N 332 
TRP OXT HXT  sing N N 333 
TYR N   CA   sing N N 334 
TYR N   H    sing N N 335 
TYR N   H2   sing N N 336 
TYR CA  C    sing N N 337 
TYR CA  CB   sing N N 338 
TYR CA  HA   sing N N 339 
TYR C   O    doub N N 340 
TYR C   OXT  sing N N 341 
TYR CB  CG   sing N N 342 
TYR CB  HB2  sing N N 343 
TYR CB  HB3  sing N N 344 
TYR CG  CD1  doub Y N 345 
TYR CG  CD2  sing Y N 346 
TYR CD1 CE1  sing Y N 347 
TYR CD1 HD1  sing N N 348 
TYR CD2 CE2  doub Y N 349 
TYR CD2 HD2  sing N N 350 
TYR CE1 CZ   doub Y N 351 
TYR CE1 HE1  sing N N 352 
TYR CE2 CZ   sing Y N 353 
TYR CE2 HE2  sing N N 354 
TYR CZ  OH   sing N N 355 
TYR OH  HH   sing N N 356 
TYR OXT HXT  sing N N 357 
VAL N   CA   sing N N 358 
VAL N   H    sing N N 359 
VAL N   H2   sing N N 360 
VAL CA  C    sing N N 361 
VAL CA  CB   sing N N 362 
VAL CA  HA   sing N N 363 
VAL C   O    doub N N 364 
VAL C   OXT  sing N N 365 
VAL CB  CG1  sing N N 366 
VAL CB  CG2  sing N N 367 
VAL CB  HB   sing N N 368 
VAL CG1 HG11 sing N N 369 
VAL CG1 HG12 sing N N 370 
VAL CG1 HG13 sing N N 371 
VAL CG2 HG21 sing N N 372 
VAL CG2 HG22 sing N N 373 
VAL CG2 HG23 sing N N 374 
VAL OXT HXT  sing N N 375 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           32000611 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   3VFM 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 21 21 21' 
_space_group.name_Hall        'P 2ac 2ab' 
_space_group.IT_number        19 
_space_group.crystal_system   orthorhombic 
_space_group.id               1 
# 
_atom_sites.entry_id                    9L4A 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.012575 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.010373 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.008258 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . SER A 1 1   ? 35.45900  28.80800  53.17300  1.000 44.76000 ? 2   SER A N   1 
ATOM   2    C CA  . SER A 1 1   ? 34.75200  27.86500  54.03000  1.000 31.00000 ? 2   SER A CA  1 
ATOM   3    C C   . SER A 1 1   ? 34.83000  26.40900  53.51800  1.000 29.56000 ? 2   SER A C   1 
ATOM   4    O O   . SER A 1 1   ? 35.18400  26.11400  52.36600  1.000 24.28000 ? 2   SER A O   1 
ATOM   5    C CB  . SER A 1 1   ? 33.29300  28.27000  54.19000  1.000 24.12000 ? 2   SER A CB  1 
ATOM   6    O OG  . SER A 1 1   ? 32.62800  28.33700  52.94400  1.000 35.35000 ? 2   SER A OG  1 
ATOM   7    N N   . HIS A 1 2   ? 34.51600  25.49400  54.41600  1.000 21.37000 ? 3   HIS A N   1 
ATOM   8    C CA  . HIS A 1 2   ? 34.68500  24.08900  54.15300  1.000 18.99000 ? 3   HIS A CA  1 
ATOM   9    C C   . HIS A 1 2   ? 33.52800  23.36100  54.80100  1.000 19.63000 ? 3   HIS A C   1 
ATOM   10   O O   . HIS A 1 2   ? 32.91300  23.86800  55.75900  1.000 19.48000 ? 3   HIS A O   1 
ATOM   11   C CB  . HIS A 1 2   ? 36.00800  23.59900  54.67600  1.000 18.39000 ? 3   HIS A CB  1 
ATOM   12   C CG  . HIS A 1 2   ? 37.18500  24.17200  53.96900  1.000 19.52000 ? 3   HIS A CG  1 
ATOM   13   N ND1 . HIS A 1 2   ? 37.51900  23.82300  52.67400  1.000 19.20000 ? 3   HIS A ND1 1 
ATOM   14   C CD2 . HIS A 1 2   ? 38.12200  25.06600  54.37500  1.000 21.99000 ? 3   HIS A CD2 1 
ATOM   15   C CE1 . HIS A 1 2   ? 38.63100  24.45000  52.32600  1.000 25.76000 ? 3   HIS A CE1 1 
ATOM   16   N NE2 . HIS A 1 2   ? 39.01200  25.22000  53.33500  1.000 20.62000 ? 3   HIS A NE2 1 
ATOM   17   N N   A SER A 1 3   ? 33.23300  22.15900  54.27300  0.500 16.98000 ? 4   SER A N   1 
ATOM   18   N N   B SER A 1 3   ? 33.23100  22.16200  54.27100  0.500 16.98000 ? 4   SER A N   1 
ATOM   19   C CA  A SER A 1 3   ? 32.13300  21.35200  54.78600  0.500 14.70000 ? 4   SER A CA  1 
ATOM   20   C CA  B SER A 1 3   ? 32.13500  21.34800  54.78100  0.500 14.72000 ? 4   SER A CA  1 
ATOM   21   C C   A SER A 1 3   ? 32.50300  19.88200  54.72600  0.500 15.39000 ? 4   SER A C   1 
ATOM   22   C C   B SER A 1 3   ? 32.50800  19.87900  54.72600  0.500 15.41000 ? 4   SER A C   1 
ATOM   23   O O   A SER A 1 3   ? 33.23500  19.44600  53.84200  0.500 14.90000 ? 4   SER A O   1 
ATOM   24   O O   B SER A 1 3   ? 33.25300  19.44400  53.85300  0.500 14.89000 ? 4   SER A O   1 
ATOM   25   C CB  A SER A 1 3   ? 30.83400  21.55100  53.99300  0.500 17.31000 ? 4   SER A CB  1 
ATOM   26   C CB  B SER A 1 3   ? 30.83600  21.55700  53.99200  0.500 17.31000 ? 4   SER A CB  1 
ATOM   27   O OG  A SER A 1 3   ? 30.30700  22.84200  54.21100  0.500 17.21000 ? 4   SER A OG  1 
ATOM   28   O OG  B SER A 1 3   ? 31.00200  21.08800  52.66100  0.500 15.88000 ? 4   SER A OG  1 
ATOM   29   N N   . MET A 1 4   ? 32.01100  19.13300  55.70000  1.000 13.60000 ? 5   MET A N   1 
ATOM   30   C CA  . MET A 1 4   ? 31.93300  17.68000  55.64000  1.000 12.59000 ? 5   MET A CA  1 
ATOM   31   C C   . MET A 1 4   ? 30.47300  17.30700  55.53100  1.000 12.89000 ? 5   MET A C   1 
ATOM   32   O O   . MET A 1 4   ? 29.67500  17.75000  56.36000  1.000 12.57000 ? 5   MET A O   1 
ATOM   33   C CB  . MET A 1 4   ? 32.44700  17.02800  56.90800  1.000 13.21000 ? 5   MET A CB  1 
ATOM   34   C CG  . MET A 1 4   ? 32.52900  15.47900  56.89500  1.000 11.36000 ? 5   MET A CG  1 
ATOM   35   S SD  . MET A 1 4   ? 33.87200  14.66600  57.84100  1.000 15.33000 ? 5   MET A SD  1 
ATOM   36   C CE  . MET A 1 4   ? 32.99500  14.89000  59.31700  1.000 15.45000 ? 5   MET A CE  1 
ATOM   37   N N   . ARG A 1 5   ? 30.13500  16.44900  54.56300  1.000 15.25000 ? 6   ARG A N   1 
ATOM   38   C CA  . ARG A 1 5   ? 28.72600  16.10000  54.36400  1.000 11.27000 ? 6   ARG A CA  1 
ATOM   39   C C   . ARG A 1 5   ? 28.56400  14.61500  54.08400  1.000 13.14000 ? 6   ARG A C   1 
ATOM   40   O O   . ARG A 1 5   ? 29.31200  14.04700  53.27600  1.000 10.19000 ? 6   ARG A O   1 
ATOM   41   C CB  . ARG A 1 5   ? 28.11700  16.90600  53.18000  1.000 14.11000 ? 6   ARG A CB  1 
ATOM   42   C CG  . ARG A 1 5   ? 28.50400  18.38100  53.16600  1.000 20.47000 ? 6   ARG A CG  1 
ATOM   43   C CD  . ARG A 1 5   ? 27.84600  19.17700  51.97300  1.000 28.28000 ? 6   ARG A CD  1 
ATOM   44   N NE  . ARG A 1 5   ? 28.07600  18.59900  50.63500  1.000 41.50000 ? 6   ARG A NE  1 
ATOM   45   C CZ  . ARG A 1 5   ? 29.27700  18.43900  50.07100  1.000 37.36000 ? 6   ARG A CZ  1 
ATOM   46   N NH1 . ARG A 1 5   ? 30.38300  18.86500  50.67500  1.000 36.81000 ? 6   ARG A NH1 1 
ATOM   47   N NH2 . ARG A 1 5   ? 29.37500  17.79200  48.90100  1.000 33.37000 ? 6   ARG A NH2 1 
ATOM   48   N N   . TYR A 1 6   ? 27.60200  13.98400  54.74700  1.000 10.47000 ? 7   TYR A N   1 
ATOM   49   C CA  . TYR A 1 6   ? 27.30600  12.57400  54.49900  1.000 9.47000  ? 7   TYR A CA  1 
ATOM   50   C C   . TYR A 1 6   ? 25.94700  12.43900  53.81400  1.000 11.48000 ? 7   TYR A C   1 
ATOM   51   O O   . TYR A 1 6   ? 25.02300  13.21300  54.09100  1.000 11.44000 ? 7   TYR A O   1 
ATOM   52   C CB  . TYR A 1 6   ? 27.32900  11.80300  55.81600  1.000 11.03000 ? 7   TYR A CB  1 
ATOM   53   C CG  . TYR A 1 6   ? 28.75800  11.38400  56.24100  1.000 11.38000 ? 7   TYR A CG  1 
ATOM   54   C CD1 . TYR A 1 6   ? 29.29200  10.15200  55.78700  1.000 12.07000 ? 7   TYR A CD1 1 
ATOM   55   C CD2 . TYR A 1 6   ? 29.54200  12.21200  57.04100  1.000 11.18000 ? 7   TYR A CD2 1 
ATOM   56   C CE1 . TYR A 1 6   ? 30.59000  9.75500   56.16400  1.000 13.16000 ? 7   TYR A CE1 1 
ATOM   57   C CE2 . TYR A 1 6   ? 30.83400  11.81700  57.47400  1.000 11.74000 ? 7   TYR A CE2 1 
ATOM   58   C CZ  . TYR A 1 6   ? 31.35300  10.59100  57.02000  1.000 14.77000 ? 7   TYR A CZ  1 
ATOM   59   O OH  . TYR A 1 6   ? 32.62800  10.17300  57.41000  1.000 14.21000 ? 7   TYR A OH  1 
ATOM   60   N N   . PHE A 1 7   ? 25.82700  11.42700  52.94000  1.000 9.67000  ? 8   PHE A N   1 
ATOM   61   C CA  . PHE A 1 7   ? 24.60700  11.21700  52.17200  1.000 9.51000  ? 8   PHE A CA  1 
ATOM   62   C C   . PHE A 1 7   ? 24.28800  9.74000   52.26600  1.000 9.02000  ? 8   PHE A C   1 
ATOM   63   O O   . PHE A 1 7   ? 25.05900  8.93500   51.74500  1.000 10.64000 ? 8   PHE A O   1 
ATOM   64   C CB  . PHE A 1 7   ? 24.80600  11.63200  50.71200  1.000 11.89000 ? 8   PHE A CB  1 
ATOM   65   C CG  . PHE A 1 7   ? 25.19200  13.08300  50.53900  1.000 11.76000 ? 8   PHE A CG  1 
ATOM   66   C CD1 . PHE A 1 7   ? 26.49300  13.52000  50.63800  1.000 12.88000 ? 8   PHE A CD1 1 
ATOM   67   C CD2 . PHE A 1 7   ? 24.20900  14.03200  50.28800  1.000 9.30000  ? 8   PHE A CD2 1 
ATOM   68   C CE1 . PHE A 1 7   ? 26.79100  14.88700  50.49500  1.000 12.09000 ? 8   PHE A CE1 1 
ATOM   69   C CE2 . PHE A 1 7   ? 24.48300  15.38300  50.14600  1.000 11.89000 ? 8   PHE A CE2 1 
ATOM   70   C CZ  . PHE A 1 7   ? 25.79400  15.81500  50.22600  1.000 13.90000 ? 8   PHE A CZ  1 
ATOM   71   N N   . TYR A 1 8   ? 23.19100  9.37500   52.95300  1.000 7.47000  ? 9   TYR A N   1 
ATOM   72   C CA  . TYR A 1 8   ? 22.79200  7.96600   53.10000  1.000 8.90000  ? 9   TYR A CA  1 
ATOM   73   C C   . TYR A 1 8   ? 21.54300  7.74000   52.28100  1.000 11.73000 ? 9   TYR A C   1 
ATOM   74   O O   . TYR A 1 8   ? 20.61800  8.55600   52.37800  1.000 8.88000  ? 9   TYR A O   1 
ATOM   75   C CB  . TYR A 1 8   ? 22.43400  7.61400   54.54400  1.000 8.12000  ? 9   TYR A CB  1 
ATOM   76   C CG  . TYR A 1 8   ? 23.59200  7.59500   55.55300  1.000 11.57000 ? 9   TYR A CG  1 
ATOM   77   C CD1 . TYR A 1 8   ? 24.85700  7.93500   55.19100  1.000 10.45000 ? 9   TYR A CD1 1 
ATOM   78   C CD2 . TYR A 1 8   ? 23.34600  7.30300   56.90000  1.000 14.63000 ? 9   TYR A CD2 1 
ATOM   79   C CE1 . TYR A 1 8   ? 25.90500  7.95200   56.13000  1.000 9.71000  ? 9   TYR A CE1 1 
ATOM   80   C CE2 . TYR A 1 8   ? 24.38300  7.30700   57.86200  1.000 15.79000 ? 9   TYR A CE2 1 
ATOM   81   C CZ  . TYR A 1 8   ? 25.67400  7.63500   57.44500  1.000 15.85000 ? 9   TYR A CZ  1 
ATOM   82   O OH  . TYR A 1 8   ? 26.68200  7.68300   58.43200  1.000 11.90000 ? 9   TYR A OH  1 
ATOM   83   N N   . THR A 1 9   ? 21.50100  6.65100   51.49100  1.000 8.67000  ? 10  THR A N   1 
ATOM   84   C CA  . THR A 1 9   ? 20.29700  6.26500   50.75800  1.000 11.10000 ? 10  THR A CA  1 
ATOM   85   C C   . THR A 1 9   ? 19.99500  4.79000   50.99400  1.000 10.15000 ? 10  THR A C   1 
ATOM   86   O O   . THR A 1 9   ? 20.89000  3.95400   50.84500  1.000 12.19000 ? 10  THR A O   1 
ATOM   87   C CB  . THR A 1 9   ? 20.51200  6.47800   49.24500  1.000 9.33000  ? 10  THR A CB  1 
ATOM   88   O OG1 . THR A 1 9   ? 20.98600  7.82000   49.01000  1.000 11.32000 ? 10  THR A OG1 1 
ATOM   89   C CG2 . THR A 1 9   ? 19.18800  6.25300   48.49600  1.000 11.58000 ? 10  THR A CG2 1 
ATOM   90   N N   . ALA A 1 10  ? 18.77300  4.46300   51.41100  1.000 8.94000  ? 11  ALA A N   1 
ATOM   91   C CA  . ALA A 1 10  ? 18.31000  3.08300   51.51500  1.000 8.05000  ? 11  ALA A CA  1 
ATOM   92   C C   . ALA A 1 10  ? 17.11200  2.90100   50.58100  1.000 14.43000 ? 11  ALA A C   1 
ATOM   93   O O   . ALA A 1 10  ? 16.17400  3.70800   50.61900  1.000 10.84000 ? 11  ALA A O   1 
ATOM   94   C CB  . ALA A 1 10  ? 17.84200  2.77300   52.96600  1.000 10.90000 ? 11  ALA A CB  1 
ATOM   95   N N   . VAL A 1 11  ? 17.13200  1.86300   49.74400  1.000 11.66000 ? 12  VAL A N   1 
ATOM   96   C CA  . VAL A 1 11  ? 16.09800  1.72800   48.72400  1.000 11.51000 ? 12  VAL A CA  1 
ATOM   97   C C   . VAL A 1 11  ? 15.61100  0.29300   48.77300  1.000 15.02000 ? 12  VAL A C   1 
ATOM   98   O O   . VAL A 1 11  ? 16.39900  -0.62700  48.49200  1.000 11.14000 ? 12  VAL A O   1 
ATOM   99   C CB  . VAL A 1 11  ? 16.62200  2.05300   47.31100  1.000 13.19000 ? 12  VAL A CB  1 
ATOM   100  C CG1 . VAL A 1 11  ? 15.44700  1.90900   46.24900  1.000 12.25000 ? 12  VAL A CG1 1 
ATOM   101  C CG2 . VAL A 1 11  ? 17.20600  3.40800   47.21500  1.000 13.68000 ? 12  VAL A CG2 1 
ATOM   102  N N   . SER A 1 12  ? 14.29700  0.09600   49.02100  1.000 10.53000 ? 13  SER A N   1 
ATOM   103  C CA  . SER A 1 12  ? 13.80100  -1.26300  48.94600  1.000 11.19000 ? 13  SER A CA  1 
ATOM   104  C C   . SER A 1 12  ? 13.53800  -1.68800  47.47500  1.000 14.02000 ? 13  SER A C   1 
ATOM   105  O O   . SER A 1 12  ? 13.41100  -0.86300  46.59100  1.000 13.83000 ? 13  SER A O   1 
ATOM   106  C CB  . SER A 1 12  ? 12.52600  -1.40000  49.78300  1.000 15.08000 ? 13  SER A CB  1 
ATOM   107  O OG  . SER A 1 12  ? 11.44200  -0.64600  49.27500  1.000 14.76000 ? 13  SER A OG  1 
ATOM   108  N N   . ARG A 1 13  ? 13.48700  -3.01500  47.23900  1.000 10.30000 ? 14  ARG A N   1 
ATOM   109  C CA  . ARG A 1 13  ? 13.36100  -3.59200  45.90500  1.000 14.67000 ? 14  ARG A CA  1 
ATOM   110  C C   . ARG A 1 13  ? 12.59100  -4.89500  46.04500  1.000 13.68000 ? 14  ARG A C   1 
ATOM   111  O O   . ARG A 1 13  ? 13.13200  -5.99900  45.89000  1.000 14.93000 ? 14  ARG A O   1 
ATOM   112  C CB  . ARG A 1 13  ? 14.72100  -3.80500  45.25200  1.000 15.73000 ? 14  ARG A CB  1 
ATOM   113  C CG  . ARG A 1 13  ? 15.77300  -4.40600  46.18000  1.000 14.79000 ? 14  ARG A CG  1 
ATOM   114  C CD  . ARG A 1 13  ? 17.18100  -4.31700  45.52600  1.000 21.03000 ? 14  ARG A CD  1 
ATOM   115  N NE  . ARG A 1 13  ? 18.12300  -4.83400  46.50500  1.000 17.05000 ? 14  ARG A NE  1 
ATOM   116  C CZ  . ARG A 1 13  ? 19.46100  -4.83200  46.38700  1.000 15.50000 ? 14  ARG A CZ  1 
ATOM   117  N NH1 . ARG A 1 13  ? 20.07000  -4.47000  45.25400  1.000 11.08000 ? 14  ARG A NH1 1 
ATOM   118  N NH2 . ARG A 1 13  ? 20.19800  -5.17900  47.45100  1.000 17.45000 ? 14  ARG A NH2 1 
ATOM   119  N N   . PRO A 1 14  ? 11.32000  -4.78900  46.37300  1.000 14.83000 ? 15  PRO A N   1 
ATOM   120  C CA  . PRO A 1 14  ? 10.47900  -5.96400  46.65500  1.000 17.33000 ? 15  PRO A CA  1 
ATOM   121  C C   . PRO A 1 14  ? 10.61900  -7.04600  45.59500  1.000 18.18000 ? 15  PRO A C   1 
ATOM   122  O O   . PRO A 1 14  ? 10.49000  -6.77800  44.39400  1.000 16.18000 ? 15  PRO A O   1 
ATOM   123  C CB  . PRO A 1 14  ? 9.05900   -5.37300  46.65900  1.000 17.64000 ? 15  PRO A CB  1 
ATOM   124  C CG  . PRO A 1 14  ? 9.22100   -3.89600  46.99700  1.000 18.41000 ? 15  PRO A CG  1 
ATOM   125  C CD  . PRO A 1 14  ? 10.58600  -3.49900  46.42400  1.000 17.93000 ? 15  PRO A CD  1 
ATOM   126  N N   . GLY A 1 15  ? 10.89000  -8.27400  46.04200  1.000 17.00000 ? 16  GLY A N   1 
ATOM   127  C CA  . GLY A 1 15  ? 11.00200  -9.38900  45.11300  1.000 16.14000 ? 16  GLY A CA  1 
ATOM   128  C C   . GLY A 1 15  ? 12.39000  -9.52100  44.53900  1.000 16.77000 ? 16  GLY A C   1 
ATOM   129  O O   . GLY A 1 15  ? 12.68300  -10.49900 43.85200  1.000 16.09000 ? 16  GLY A O   1 
ATOM   130  N N   . ARG A 1 16  ? 13.26900  -8.59300  44.86100  1.000 13.46000 ? 17  ARG A N   1 
ATOM   131  C CA  . ARG A 1 16  ? 14.65200  -8.62000  44.45200  1.000 13.66000 ? 17  ARG A CA  1 
ATOM   132  C C   . ARG A 1 16  ? 15.60100  -8.55300  45.64600  1.000 14.52000 ? 17  ARG A C   1 
ATOM   133  O O   . ARG A 1 16  ? 16.67500  -7.97000  45.53300  1.000 15.69000 ? 17  ARG A O   1 
ATOM   134  C CB  . ARG A 1 16  ? 14.94700  -7.47400  43.46800  1.000 14.32000 ? 17  ARG A CB  1 
ATOM   135  C CG  . ARG A 1 16  ? 14.21900  -7.67200  42.11100  1.000 20.09000 ? 17  ARG A CG  1 
ATOM   136  C CD  . ARG A 1 16  ? 14.51500  -6.46300  41.19400  1.000 27.50000 ? 17  ARG A CD  1 
ATOM   137  N NE  . ARG A 1 16  ? 13.65600  -5.33600  41.55300  1.000 40.20000 ? 17  ARG A NE  1 
ATOM   138  C CZ  . ARG A 1 16  ? 14.05900  -4.08600  41.79000  1.000 44.91000 ? 17  ARG A CZ  1 
ATOM   139  N NH1 . ARG A 1 16  ? 15.35100  -3.75000  41.80300  1.000 44.92000 ? 17  ARG A NH1 1 
ATOM   140  N NH2 . ARG A 1 16  ? 13.14300  -3.14900  42.03700  1.000 34.06000 ? 17  ARG A NH2 1 
ATOM   141  N N   . GLY A 1 17  ? 15.26000  -9.16900  46.76800  1.000 13.88000 ? 18  GLY A N   1 
ATOM   142  C CA  . GLY A 1 17  ? 16.18200  -9.17200  47.91100  1.000 16.14000 ? 18  GLY A CA  1 
ATOM   143  C C   . GLY A 1 17  ? 15.96500  -8.00500  48.87700  1.000 15.58000 ? 18  GLY A C   1 
ATOM   144  O O   . GLY A 1 17  ? 14.97000  -7.28000  48.79300  1.000 13.39000 ? 18  GLY A O   1 
ATOM   145  N N   . GLU A 1 18  ? 16.90100  -7.85600  49.83900  1.000 17.85000 ? 19  GLU A N   1 
ATOM   146  C CA  . GLU A 1 18  ? 16.82700  -6.84700  50.91300  1.000 14.96000 ? 19  GLU A CA  1 
ATOM   147  C C   . GLU A 1 18  ? 17.09800  -5.44800  50.35800  1.000 12.03000 ? 19  GLU A C   1 
ATOM   148  O O   . GLU A 1 18  ? 17.72000  -5.30900  49.29800  1.000 11.53000 ? 19  GLU A O   1 
ATOM   149  C CB  . GLU A 1 18  ? 17.87100  -7.15600  52.03100  1.000 14.78000 ? 19  GLU A CB  1 
ATOM   150  C CG  . GLU A 1 18  ? 17.60300  -8.48400  52.64100  1.000 31.42000 ? 19  GLU A CG  1 
ATOM   151  C CD  . GLU A 1 18  ? 16.61700  -8.44900  53.80000  1.000 44.26000 ? 19  GLU A CD  1 
ATOM   152  O OE1 . GLU A 1 18  ? 15.68200  -7.61300  53.72700  1.000 52.73000 ? 19  GLU A OE1 1 
ATOM   153  O OE2 . GLU A 1 18  ? 16.75700  -9.24000  54.77200  1.000 47.78000 ? 19  GLU A OE2 1 
ATOM   154  N N   . PRO A 1 19  ? 16.68800  -4.38900  51.08000  1.000 13.56000 ? 20  PRO A N   1 
ATOM   155  C CA  . PRO A 1 19  ? 16.97400  -3.02100  50.61100  1.000 10.85000 ? 20  PRO A CA  1 
ATOM   156  C C   . PRO A 1 19  ? 18.48000  -2.79700  50.54300  1.000 15.72000 ? 20  PRO A C   1 
ATOM   157  O O   . PRO A 1 19  ? 19.25300  -3.35500  51.33800  1.000 16.23000 ? 20  PRO A O   1 
ATOM   158  C CB  . PRO A 1 19  ? 16.32600  -2.10500  51.67900  1.000 11.46000 ? 20  PRO A CB  1 
ATOM   159  C CG  . PRO A 1 19  ? 15.24700  -2.95800  52.28600  1.000 13.25000 ? 20  PRO A CG  1 
ATOM   160  C CD  . PRO A 1 19  ? 15.81900  -4.40200  52.27500  1.000 13.47000 ? 20  PRO A CD  1 
ATOM   161  N N   . ARG A 1 20  ? 18.88900  -2.01200  49.55600  1.000 11.46000 ? 21  ARG A N   1 
ATOM   162  C CA  . ARG A 1 20  ? 20.29800  -1.65000  49.38400  1.000 11.78000 ? 21  ARG A CA  1 
ATOM   163  C C   . ARG A 1 20  ? 20.56900  -0.35800  50.15100  1.000 12.82000 ? 21  ARG A C   1 
ATOM   164  O O   . ARG A 1 20  ? 19.77200  0.56700   50.10300  1.000 12.65000 ? 21  ARG A O   1 
ATOM   165  C CB  . ARG A 1 20  ? 20.59800  -1.41000  47.91700  1.000 12.33000 ? 21  ARG A CB  1 
ATOM   166  C CG  . ARG A 1 20  ? 22.12400  -1.11700  47.61600  1.000 13.68000 ? 21  ARG A CG  1 
ATOM   167  C CD  . ARG A 1 20  ? 22.32300  -0.99600  46.11200  1.000 18.98000 ? 21  ARG A CD  1 
ATOM   168  N NE  . ARG A 1 20  ? 23.71000  -0.87800  45.64700  1.000 21.36000 ? 21  ARG A NE  1 
ATOM   169  C CZ  . ARG A 1 20  ? 24.00400  -0.78200  44.35700  1.000 26.45000 ? 21  ARG A CZ  1 
ATOM   170  N NH1 . ARG A 1 20  ? 23.04400  -0.75200  43.43000  1.000 26.35000 ? 21  ARG A NH1 1 
ATOM   171  N NH2 . ARG A 1 20  ? 25.27700  -0.75700  43.97800  1.000 20.97000 ? 21  ARG A NH2 1 
ATOM   172  N N   . PHE A 1 21  ? 21.67800  -0.30400  50.85100  1.000 10.73000 ? 22  PHE A N   1 
ATOM   173  C CA  . PHE A 1 21  ? 22.08300  0.89300   51.61700  1.000 9.80000  ? 22  PHE A CA  1 
ATOM   174  C C   . PHE A 1 21  ? 23.39900  1.39000   51.02900  1.000 11.23000 ? 22  PHE A C   1 
ATOM   175  O O   . PHE A 1 21  ? 24.33500  0.58700   50.86300  1.000 10.66000 ? 22  PHE A O   1 
ATOM   176  C CB  . PHE A 1 21  ? 22.24700  0.53300   53.09000  1.000 10.80000 ? 22  PHE A CB  1 
ATOM   177  C CG  . PHE A 1 21  ? 22.82400  1.64300   53.94400  1.000 13.81000 ? 22  PHE A CG  1 
ATOM   178  C CD1 . PHE A 1 21  ? 22.00800  2.61000   54.53100  1.000 14.90000 ? 22  PHE A CD1 1 
ATOM   179  C CD2 . PHE A 1 21  ? 24.17500  1.69700   54.17200  1.000 10.61000 ? 22  PHE A CD2 1 
ATOM   180  C CE1 . PHE A 1 21  ? 22.54900  3.62400   55.37500  1.000 14.36000 ? 22  PHE A CE1 1 
ATOM   181  C CE2 . PHE A 1 21  ? 24.72300  2.69700   54.99300  1.000 13.86000 ? 22  PHE A CE2 1 
ATOM   182  C CZ  . PHE A 1 21  ? 23.92900  3.65800   55.55600  1.000 11.90000 ? 22  PHE A CZ  1 
ATOM   183  N N   . ILE A 1 22  ? 23.47600  2.68800   50.71600  1.000 8.78000  ? 23  ILE A N   1 
ATOM   184  C CA  . ILE A 1 22  ? 24.70400  3.33200   50.17800  1.000 8.62000  ? 23  ILE A CA  1 
ATOM   185  C C   . ILE A 1 22  ? 24.97800  4.53600   51.04600  1.000 11.38000 ? 23  ILE A C   1 
ATOM   186  O O   . ILE A 1 22  ? 24.05900  5.31400   51.29900  1.000 11.86000 ? 23  ILE A O   1 
ATOM   187  C CB  . ILE A 1 22  ? 24.51400  3.79700   48.72800  1.000 11.45000 ? 23  ILE A CB  1 
ATOM   188  C CG1 . ILE A 1 22  ? 24.23800  2.53800   47.90400  1.000 17.18000 ? 23  ILE A CG1 1 
ATOM   189  C CG2 . ILE A 1 22  ? 25.79300  4.55800   48.21900  1.000 11.47000 ? 23  ILE A CG2 1 
ATOM   190  C CD1 . ILE A 1 22  ? 24.14400  2.75900   46.42300  1.000 22.33000 ? 23  ILE A CD1 1 
ATOM   191  N N   . ALA A 1 23  ? 26.23600  4.70700   51.47300  1.000 8.38000  ? 24  ALA A N   1 
ATOM   192  C CA  . ALA A 1 23  ? 26.65100  5.88400   52.22400  1.000 11.18000 ? 24  ALA A CA  1 
ATOM   193  C C   . ALA A 1 23  ? 27.83800  6.47000   51.49600  1.000 11.45000 ? 24  ALA A C   1 
ATOM   194  O O   . ALA A 1 23  ? 28.74500  5.71400   51.08800  1.000 12.52000 ? 24  ALA A O   1 
ATOM   195  C CB  . ALA A 1 23  ? 27.06200  5.52800   53.67600  1.000 9.78000  ? 24  ALA A CB  1 
ATOM   196  N N   . VAL A 1 24  ? 27.83200  7.81200   51.31900  1.000 10.02000 ? 25  VAL A N   1 
ATOM   197  C CA  . VAL A 1 24  ? 29.01000  8.48400   50.76600  1.000 11.29000 ? 25  VAL A CA  1 
ATOM   198  C C   . VAL A 1 24  ? 29.30200  9.69100   51.64700  1.000 11.86000 ? 25  VAL A C   1 
ATOM   199  O O   . VAL A 1 24  ? 28.39300  10.30700  52.21400  1.000 10.10000 ? 25  VAL A O   1 
ATOM   200  C CB  . VAL A 1 24  ? 28.83400  8.89000   49.29900  1.000 14.55000 ? 25  VAL A CB  1 
ATOM   201  C CG1 . VAL A 1 24  ? 28.56600  7.64600   48.44400  1.000 11.55000 ? 25  VAL A CG1 1 
ATOM   202  C CG2 . VAL A 1 24  ? 27.69900  9.89300   49.11200  1.000 17.54000 ? 25  VAL A CG2 1 
ATOM   203  N N   . GLY A 1 25  ? 30.58300  9.97400   51.80100  1.000 11.80000 ? 26  GLY A N   1 
ATOM   204  C CA  . GLY A 1 25  ? 31.02400  11.10900  52.59500  1.000 10.91000 ? 26  GLY A CA  1 
ATOM   205  C C   . GLY A 1 25  ? 31.94800  11.96000  51.73800  1.000 13.08000 ? 26  GLY A C   1 
ATOM   206  O O   . GLY A 1 25  ? 32.76000  11.44000  50.97300  1.000 11.30000 ? 26  GLY A O   1 
ATOM   207  N N   . TYR A 1 26  ? 31.79500  13.28400  51.86000  1.000 11.74000 ? 27  TYR A N   1 
ATOM   208  C CA  . TYR A 1 26  ? 32.56900  14.28100  51.12000  1.000 13.72000 ? 27  TYR A CA  1 
ATOM   209  C C   . TYR A 1 26  ? 33.18500  15.30000  52.04800  1.000 13.41000 ? 27  TYR A C   1 
ATOM   210  O O   . TYR A 1 26  ? 32.53600  15.71300  53.01600  1.000 12.28000 ? 27  TYR A O   1 
ATOM   211  C CB  . TYR A 1 26  ? 31.66400  15.14200  50.19100  1.000 13.54000 ? 27  TYR A CB  1 
ATOM   212  C CG  . TYR A 1 26  ? 31.07900  14.40500  48.99800  1.000 14.85000 ? 27  TYR A CG  1 
ATOM   213  C CD1 . TYR A 1 26  ? 29.95100  13.57400  49.11000  1.000 15.99000 ? 27  TYR A CD1 1 
ATOM   214  C CD2 . TYR A 1 26  ? 31.65400  14.56900  47.76300  1.000 14.12000 ? 27  TYR A CD2 1 
ATOM   215  C CE1 . TYR A 1 26  ? 29.40900  12.93600  47.94600  1.000 15.88000 ? 27  TYR A CE1 1 
ATOM   216  C CE2 . TYR A 1 26  ? 31.14100  13.96400  46.60800  1.000 14.65000 ? 27  TYR A CE2 1 
ATOM   217  C CZ  . TYR A 1 26  ? 30.00600  13.19600  46.70100  1.000 18.03000 ? 27  TYR A CZ  1 
ATOM   218  O OH  . TYR A 1 26  ? 29.59200  12.62300  45.54600  1.000 21.40000 ? 27  TYR A OH  1 
ATOM   219  N N   . VAL A 1 27  ? 34.37400  15.79800  51.67300  1.000 11.91000 ? 28  VAL A N   1 
ATOM   220  C CA  . VAL A 1 27  ? 34.82200  17.11000  52.15400  1.000 14.80000 ? 28  VAL A CA  1 
ATOM   221  C C   . VAL A 1 27  ? 34.68300  18.04700  50.95200  1.000 14.55000 ? 28  VAL A C   1 
ATOM   222  O O   . VAL A 1 27  ? 35.27500  17.79400  49.89200  1.000 12.28000 ? 28  VAL A O   1 
ATOM   223  C CB  . VAL A 1 27  ? 36.26700  17.09500  52.69400  1.000 14.30000 ? 28  VAL A CB  1 
ATOM   224  C CG1 . VAL A 1 27  ? 36.75000  18.56300  52.97900  1.000 13.37000 ? 28  VAL A CG1 1 
ATOM   225  C CG2 . VAL A 1 27  ? 36.35700  16.24800  54.00400  1.000 14.33000 ? 28  VAL A CG2 1 
ATOM   226  N N   . ASP A 1 28  ? 33.93300  19.12600  51.13600  1.000 13.18000 ? 29  ASP A N   1 
ATOM   227  C CA  . ASP A 1 28  ? 33.63400  19.99700  50.00400  1.000 15.16000 ? 29  ASP A CA  1 
ATOM   228  C C   . ASP A 1 28  ? 33.17000  19.16400  48.82300  1.000 15.57000 ? 29  ASP A C   1 
ATOM   229  O O   . ASP A 1 28  ? 32.16300  18.44300  48.90500  1.000 14.64000 ? 29  ASP A O   1 
ATOM   230  C CB  . ASP A 1 28  ? 34.85100  20.87100  49.65600  1.000 14.77000 ? 29  ASP A CB  1 
ATOM   231  C CG  . ASP A 1 28  ? 35.26400  21.69100  50.84600  1.000 17.90000 ? 29  ASP A CG  1 
ATOM   232  O OD1 . ASP A 1 28  ? 34.35400  22.12900  51.56100  1.000 21.58000 ? 29  ASP A OD1 1 
ATOM   233  O OD2 . ASP A 1 28  ? 36.47500  21.93200  51.04900  1.000 20.33000 ? 29  ASP A OD2 1 
ATOM   234  N N   . ASP A 1 29  ? 33.82400  19.30500  47.68000  1.000 12.16000 ? 30  ASP A N   1 
ATOM   235  C CA  . ASP A 1 29  ? 33.40200  18.57100  46.49500  1.000 13.70000 ? 30  ASP A CA  1 
ATOM   236  C C   . ASP A 1 29  ? 34.18500  17.30300  46.26000  1.000 16.01000 ? 30  ASP A C   1 
ATOM   237  O O   . ASP A 1 29  ? 34.18800  16.84100  45.12500  1.000 16.12000 ? 30  ASP A O   1 
ATOM   238  C CB  . ASP A 1 29  ? 33.54300  19.44300  45.23900  1.000 16.90000 ? 30  ASP A CB  1 
ATOM   239  C CG  . ASP A 1 29  ? 32.63400  20.63200  45.26100  1.000 20.01000 ? 30  ASP A CG  1 
ATOM   240  O OD1 . ASP A 1 29  ? 31.54100  20.57000  45.85900  1.000 16.23000 ? 30  ASP A OD1 1 
ATOM   241  O OD2 . ASP A 1 29  ? 33.01600  21.64200  44.68800  1.000 21.90000 ? 30  ASP A OD2 1 
ATOM   242  N N   . THR A 1 30  ? 34.90600  16.77200  47.27700  1.000 12.91000 ? 31  THR A N   1 
ATOM   243  C CA  . THR A 1 30  ? 35.78500  15.60900  47.12800  1.000 14.24000 ? 31  THR A CA  1 
ATOM   244  C C   . THR A 1 30  ? 35.23200  14.43900  47.94500  1.000 16.26000 ? 31  THR A C   1 
ATOM   245  O O   . THR A 1 30  ? 35.19600  14.49800  49.17900  1.000 13.33000 ? 31  THR A O   1 
ATOM   246  C CB  . THR A 1 30  ? 37.22400  15.92700  47.60700  1.000 14.96000 ? 31  THR A CB  1 
ATOM   247  O OG1 . THR A 1 30  ? 37.72400  17.04000  46.83800  1.000 15.59000 ? 31  THR A OG1 1 
ATOM   248  C CG2 . THR A 1 30  ? 38.15600  14.71300  47.35800  1.000 15.14000 ? 31  THR A CG2 1 
ATOM   249  N N   . GLN A 1 31  ? 34.83700  13.36500  47.27200  1.000 14.00000 ? 32  GLN A N   1 
ATOM   250  C CA  . GLN A 1 31  ? 34.41800  12.17300  47.99100  1.000 11.10000 ? 32  GLN A CA  1 
ATOM   251  C C   . GLN A 1 31  ? 35.58600  11.50400  48.68900  1.000 15.22000 ? 32  GLN A C   1 
ATOM   252  O O   . GLN A 1 31  ? 36.67400  11.31900  48.10300  1.000 14.70000 ? 32  GLN A O   1 
ATOM   253  C CB  . GLN A 1 31  ? 33.77800  11.16400  47.00600  1.000 12.67000 ? 32  GLN A CB  1 
ATOM   254  C CG  . GLN A 1 31  ? 33.03200  9.98700   47.73800  1.000 15.58000 ? 32  GLN A CG  1 
ATOM   255  C CD  . GLN A 1 31  ? 32.75600  8.83200   46.78900  1.000 18.08000 ? 32  GLN A CD  1 
ATOM   256  O OE1 . GLN A 1 31  ? 33.06400  8.91000   45.59700  1.000 17.84000 ? 32  GLN A OE1 1 
ATOM   257  N NE2 . GLN A 1 31  ? 32.10900  7.80500   47.28200  1.000 14.81000 ? 32  GLN A NE2 1 
ATOM   258  N N   . PHE A 1 32  ? 35.37600  11.08800  49.93400  1.000 16.43000 ? 33  PHE A N   1 
ATOM   259  C CA  . PHE A 1 32  ? 36.47500  10.38600  50.61300  1.000 12.19000 ? 33  PHE A CA  1 
ATOM   260  C C   . PHE A 1 32  ? 36.09800  9.00700   51.11700  1.000 16.54000 ? 33  PHE A C   1 
ATOM   261  O O   . PHE A 1 32  ? 37.00600  8.21900   51.42700  1.000 11.69000 ? 33  PHE A O   1 
ATOM   262  C CB  . PHE A 1 32  ? 37.05600  11.23500  51.76400  1.000 12.43000 ? 33  PHE A CB  1 
ATOM   263  C CG  . PHE A 1 32  ? 36.09900  11.44000  52.99500  1.000 14.41000 ? 33  PHE A CG  1 
ATOM   264  C CD1 . PHE A 1 32  ? 35.18400  12.50700  53.03300  1.000 11.55000 ? 33  PHE A CD1 1 
ATOM   265  C CD2 . PHE A 1 32  ? 36.12700  10.56200  54.09200  1.000 11.23000 ? 33  PHE A CD2 1 
ATOM   266  C CE1 . PHE A 1 32  ? 34.31700  12.73200  54.09200  1.000 10.22000 ? 33  PHE A CE1 1 
ATOM   267  C CE2 . PHE A 1 32  ? 35.20300  10.78800  55.20500  1.000 14.22000 ? 33  PHE A CE2 1 
ATOM   268  C CZ  . PHE A 1 32  ? 34.32300  11.87700  55.20100  1.000 10.02000 ? 33  PHE A CZ  1 
ATOM   269  N N   . VAL A 1 33  ? 34.80500  8.65600   51.14600  1.000 10.53000 ? 34  VAL A N   1 
ATOM   270  C CA  . VAL A 1 33  ? 34.41300  7.33600   51.61900  1.000 9.44000  ? 34  VAL A CA  1 
ATOM   271  C C   . VAL A 1 33  ? 33.14400  6.88700   50.90200  1.000 12.95000 ? 34  VAL A C   1 
ATOM   272  O O   . VAL A 1 33  ? 32.32500  7.69400   50.45200  1.000 10.29000 ? 34  VAL A O   1 
ATOM   273  C CB  . VAL A 1 33  ? 34.25900  7.34200   53.15300  1.000 12.48000 ? 34  VAL A CB  1 
ATOM   274  C CG1 . VAL A 1 33  ? 33.07600  8.22500   53.52600  1.000 12.51000 ? 34  VAL A CG1 1 
ATOM   275  C CG2 . VAL A 1 33  ? 34.02600  5.83700   53.72000  1.000 9.02000  ? 34  VAL A CG2 1 
ATOM   276  N N   . ARG A 1 34  ? 32.95100  5.58300   50.92200  1.000 10.43000 ? 35  ARG A N   1 
ATOM   277  C CA  . ARG A 1 34  ? 31.73500  4.97000   50.47200  1.000 11.83000 ? 35  ARG A CA  1 
ATOM   278  C C   . ARG A 1 34  ? 31.49500  3.63900   51.14100  1.000 10.39000 ? 35  ARG A C   1 
ATOM   279  O O   . ARG A 1 34  ? 32.39200  2.98700   51.55400  1.000 13.99000 ? 35  ARG A O   1 
ATOM   280  C CB  . ARG A 1 34  ? 31.70700  4.79200   48.99300  1.000 12.15000 ? 35  ARG A CB  1 
ATOM   281  C CG  . ARG A 1 34  ? 32.67300  3.78100   48.48900  1.000 16.47000 ? 35  ARG A CG  1 
ATOM   282  C CD  . ARG A 1 34  ? 32.13000  2.40900   48.49900  1.000 24.65000 ? 35  ARG A CD  1 
ATOM   283  N NE  . ARG A 1 34  ? 31.88100  2.04700   47.15200  1.000 44.00000 ? 35  ARG A NE  1 
ATOM   284  C CZ  . ARG A 1 34  ? 31.91200  0.82600   46.65900  1.000 40.11000 ? 35  ARG A CZ  1 
ATOM   285  N NH1 . ARG A 1 34  ? 32.17100  -0.20700  47.40500  1.000 40.91000 ? 35  ARG A NH1 1 
ATOM   286  N NH2 . ARG A 1 34  ? 31.65300  0.66300   45.40600  1.000 53.56000 ? 35  ARG A NH2 1 
ATOM   287  N N   . PHE A 1 35  ? 30.24500  3.32600   51.31800  1.000 8.88000  ? 36  PHE A N   1 
ATOM   288  C CA  . PHE A 1 35  ? 29.85400  2.00900   51.75200  1.000 10.55000 ? 36  PHE A CA  1 
ATOM   289  C C   . PHE A 1 35  ? 28.69200  1.59700   50.87100  1.000 13.54000 ? 36  PHE A C   1 
ATOM   290  O O   . PHE A 1 35  ? 27.78800  2.40200   50.66500  1.000 11.97000 ? 36  PHE A O   1 
ATOM   291  C CB  . PHE A 1 35  ? 29.46600  2.01800   53.23500  1.000 11.72000 ? 36  PHE A CB  1 
ATOM   292  C CG  . PHE A 1 35  ? 28.98300  0.68100   53.74200  1.000 12.70000 ? 36  PHE A CG  1 
ATOM   293  C CD1 . PHE A 1 35  ? 27.64400  0.34600   53.61300  1.000 10.39000 ? 36  PHE A CD1 1 
ATOM   294  C CD2 . PHE A 1 35  ? 29.87500  -0.22000  54.38600  1.000 11.34000 ? 36  PHE A CD2 1 
ATOM   295  C CE1 . PHE A 1 35  ? 27.14900  -0.88900  54.03900  1.000 13.60000 ? 36  PHE A CE1 1 
ATOM   296  C CE2 . PHE A 1 35  ? 29.37000  -1.44100  54.86400  1.000 14.98000 ? 36  PHE A CE2 1 
ATOM   297  C CZ  . PHE A 1 35  ? 27.98600  -1.77300  54.70200  1.000 14.55000 ? 36  PHE A CZ  1 
ATOM   298  N N   . ASP A 1 36  ? 28.72100  0.37500   50.33600  1.000 9.87000  ? 37  ASP A N   1 
ATOM   299  C CA  . ASP A 1 36  ? 27.65200  -0.11300  49.45200  1.000 13.59000 ? 37  ASP A CA  1 
ATOM   300  C C   . ASP A 1 36  ? 27.27100  -1.51400  49.92900  1.000 17.22000 ? 37  ASP A C   1 
ATOM   301  O O   . ASP A 1 36  ? 28.10600  -2.42700  49.87600  1.000 13.82000 ? 37  ASP A O   1 
ATOM   302  C CB  . ASP A 1 36  ? 28.12600  -0.12500  48.01000  1.000 14.35000 ? 37  ASP A CB  1 
ATOM   303  C CG  . ASP A 1 36  ? 27.01800  -0.51500  47.01100  1.000 19.40000 ? 37  ASP A CG  1 
ATOM   304  O OD1 . ASP A 1 36  ? 26.00100  -1.03900  47.44800  1.000 13.75000 ? 37  ASP A OD1 1 
ATOM   305  O OD2 . ASP A 1 36  ? 27.17400  -0.19000  45.79400  1.000 21.01000 ? 37  ASP A OD2 1 
ATOM   306  N N   . SER A 1 37  ? 26.03300  -1.68400  50.44700  1.000 13.83000 ? 38  SER A N   1 
ATOM   307  C CA  . SER A 1 37  ? 25.66400  -2.95200  51.03700  1.000 15.84000 ? 38  SER A CA  1 
ATOM   308  C C   . SER A 1 37  ? 25.64600  -4.05100  50.00200  1.000 14.82000 ? 38  SER A C   1 
ATOM   309  O O   . SER A 1 37  ? 25.60100  -5.23000  50.36400  1.000 16.11000 ? 38  SER A O   1 
ATOM   310  C CB  . SER A 1 37  ? 24.29200  -2.88400  51.75400  1.000 14.55000 ? 38  SER A CB  1 
ATOM   311  O OG  . SER A 1 37  ? 23.30400  -2.60800  50.78700  1.000 12.71000 ? 38  SER A OG  1 
ATOM   312  N N   . ASP A 1 38  ? 25.63100  -3.69800  48.73500  1.000 15.32000 ? 39  ASP A N   1 
ATOM   313  C CA  . ASP A 1 38  ? 25.64500  -4.69300  47.68500  1.000 15.42000 ? 39  ASP A CA  1 
ATOM   314  C C   . ASP A 1 38  ? 27.04800  -5.17700  47.31800  1.000 21.45000 ? 39  ASP A C   1 
ATOM   315  O O   . ASP A 1 38  ? 27.14200  -6.13000  46.52700  1.000 14.31000 ? 39  ASP A O   1 
ATOM   316  C CB  . ASP A 1 38  ? 24.98600  -4.14400  46.42800  1.000 13.85000 ? 39  ASP A CB  1 
ATOM   317  C CG  . ASP A 1 38  ? 23.49900  -4.46100  46.37600  1.000 13.29000 ? 39  ASP A CG  1 
ATOM   318  O OD1 . ASP A 1 38  ? 22.95800  -4.93000  47.39700  1.000 14.40000 ? 39  ASP A OD1 1 
ATOM   319  O OD2 . ASP A 1 38  ? 22.87400  -4.27000  45.32500  1.000 16.50000 ? 39  ASP A OD2 1 
ATOM   320  N N   . ALA A 1 39  ? 28.11700  -4.52800  47.84400  1.000 17.59000 ? 40  ALA A N   1 
ATOM   321  C CA  . ALA A 1 39  ? 29.49200  -4.92000  47.46900  1.000 18.07000 ? 40  ALA A CA  1 
ATOM   322  C C   . ALA A 1 39  ? 29.78500  -6.36600  47.87300  1.000 18.77000 ? 40  ALA A C   1 
ATOM   323  O O   . ALA A 1 39  ? 29.18100  -6.92000  48.78800  1.000 19.26000 ? 40  ALA A O   1 
ATOM   324  C CB  . ALA A 1 39  ? 30.52200  -4.01500  48.15400  1.000 18.51000 ? 40  ALA A CB  1 
ATOM   325  N N   . ALA A 1 40  ? 30.79100  -6.96400  47.21600  1.000 23.46000 ? 41  ALA A N   1 
ATOM   326  C CA  . ALA A 1 40  ? 31.12900  -8.36800  47.50500  1.000 27.26000 ? 41  ALA A CA  1 
ATOM   327  C C   . ALA A 1 40  ? 31.47300  -8.57800  48.96700  1.000 30.14000 ? 41  ALA A C   1 
ATOM   328  O O   . ALA A 1 40  ? 31.09100  -9.58400  49.58500  1.000 31.01000 ? 41  ALA A O   1 
ATOM   329  C CB  . ALA A 1 40  ? 32.31600  -8.79000  46.63200  1.000 32.33000 ? 41  ALA A CB  1 
ATOM   330  N N   . SER A 1 41  ? 32.22700  -7.66200  49.54100  1.000 23.43000 ? 42  SER A N   1 
ATOM   331  C CA  . SER A 1 41  ? 32.56600  -7.74900  50.96600  1.000 23.78000 ? 42  SER A CA  1 
ATOM   332  C C   . SER A 1 41  ? 32.39300  -6.34200  51.51900  1.000 21.23000 ? 42  SER A C   1 
ATOM   333  O O   . SER A 1 41  ? 33.35800  -5.54700  51.51900  1.000 21.87000 ? 42  SER A O   1 
ATOM   334  C CB  . SER A 1 41  ? 33.99400  -8.26500  51.15700  1.000 39.61000 ? 42  SER A CB  1 
ATOM   335  O OG  . SER A 1 41  ? 33.98700  -9.68000  50.98600  1.000 50.86000 ? 42  SER A OG  1 
ATOM   336  N N   . PRO A 1 42  ? 31.16200  -5.97300  51.90500  1.000 18.12000 ? 43  PRO A N   1 
ATOM   337  C CA  . PRO A 1 42  ? 30.85200  -4.56100  52.18800  1.000 12.63000 ? 43  PRO A CA  1 
ATOM   338  C C   . PRO A 1 42  ? 31.72800  -4.00400  53.30500  1.000 18.73000 ? 43  PRO A C   1 
ATOM   339  O O   . PRO A 1 42  ? 31.80500  -4.54600  54.40400  1.000 21.04000 ? 43  PRO A O   1 
ATOM   340  C CB  . PRO A 1 42  ? 29.35700  -4.57900  52.58200  1.000 17.71000 ? 43  PRO A CB  1 
ATOM   341  C CG  . PRO A 1 42  ? 28.79200  -5.88300  52.04100  1.000 21.07000 ? 43  PRO A CG  1 
ATOM   342  C CD  . PRO A 1 42  ? 29.99300  -6.87200  52.08600  1.000 17.30000 ? 43  PRO A CD  1 
ATOM   343  N N   . ARG A 1 43  ? 32.38000  -2.88500  53.02200  1.000 16.17000 ? 44  ARG A N   1 
ATOM   344  C CA  . ARG A 1 43  ? 33.16100  -2.23200  54.04500  1.000 15.06000 ? 44  ARG A CA  1 
ATOM   345  C C   . ARG A 1 43  ? 33.19200  -0.76800  53.70200  1.000 12.35000 ? 44  ARG A C   1 
ATOM   346  O O   . ARG A 1 43  ? 32.94600  -0.39300  52.56700  1.000 14.65000 ? 44  ARG A O   1 
ATOM   347  C CB  . ARG A 1 43  ? 34.57600  -2.87500  54.13100  1.000 18.56000 ? 44  ARG A CB  1 
ATOM   348  C CG  . ARG A 1 43  ? 35.49600  -2.43200  53.03200  1.000 27.73000 ? 44  ARG A CG  1 
ATOM   349  C CD  . ARG A 1 43  ? 36.92300  -3.15000  53.01600  1.000 42.11000 ? 44  ARG A CD  1 
ATOM   350  N NE  . ARG A 1 43  ? 37.51800  -3.15400  51.66900  1.000 34.41000 ? 44  ARG A NE  1 
ATOM   351  C CZ  . ARG A 1 43  ? 36.96800  -3.72100  50.60000  1.000 35.78000 ? 44  ARG A CZ  1 
ATOM   352  N NH1 . ARG A 1 43  ? 35.95500  -4.57700  50.71000  1.000 47.74000 ? 44  ARG A NH1 1 
ATOM   353  N NH2 . ARG A 1 43  ? 37.46100  -3.46000  49.39300  1.000 46.75000 ? 44  ARG A NH2 1 
ATOM   354  N N   . GLY A 1 44  ? 33.50100  0.07300   54.68000  1.000 13.28000 ? 45  GLY A N   1 
ATOM   355  C CA  . GLY A 1 44  ? 33.80600  1.45400   54.34600  1.000 12.91000 ? 45  GLY A CA  1 
ATOM   356  C C   . GLY A 1 44  ? 35.11800  1.44100   53.58200  1.000 15.41000 ? 45  GLY A C   1 
ATOM   357  O O   . GLY A 1 44  ? 36.05400  0.73700   53.96700  1.000 14.90000 ? 45  GLY A O   1 
ATOM   358  N N   . GLU A 1 45  ? 35.17000  2.14900   52.46000  1.000 12.50000 ? 46  GLU A N   1 
ATOM   359  C CA  . GLU A 1 45  ? 36.36200  2.17200   51.61600  1.000 15.03000 ? 46  GLU A CA  1 
ATOM   360  C C   . GLU A 1 45  ? 36.80900  3.59000   51.31800  1.000 16.46000 ? 46  GLU A C   1 
ATOM   361  O O   . GLU A 1 45  ? 35.98600  4.46200   51.03800  1.000 13.37000 ? 46  GLU A O   1 
ATOM   362  C CB  . GLU A 1 45  ? 36.12200  1.49500   50.26900  1.000 18.61000 ? 46  GLU A CB  1 
ATOM   363  C CG  . GLU A 1 45  ? 35.68400  0.06000   50.31500  1.000 20.19000 ? 46  GLU A CG  1 
ATOM   364  C CD  . GLU A 1 45  ? 35.42400  -0.50600  48.89900  1.000 26.16000 ? 46  GLU A CD  1 
ATOM   365  O OE1 . GLU A 1 45  ? 35.74400  0.15800   47.89900  1.000 33.11000 ? 46  GLU A OE1 1 
ATOM   366  O OE2 . GLU A 1 45  ? 34.83500  -1.57000  48.79700  1.000 35.81000 ? 46  GLU A OE2 1 
ATOM   367  N N   . PRO A 1 46  ? 38.11200  3.83500   51.32600  1.000 14.03000 ? 47  PRO A N   1 
ATOM   368  C CA  . PRO A 1 46  ? 38.60200  5.18200   51.05500  1.000 13.35000 ? 47  PRO A CA  1 
ATOM   369  C C   . PRO A 1 46  ? 38.40800  5.52500   49.59600  1.000 16.91000 ? 47  PRO A C   1 
ATOM   370  O O   . PRO A 1 46  ? 38.47200  4.66000   48.70400  1.000 16.14000 ? 47  PRO A O   1 
ATOM   371  C CB  . PRO A 1 46  ? 40.09700  5.08400   51.41600  1.000 13.49000 ? 47  PRO A CB  1 
ATOM   372  C CG  . PRO A 1 46  ? 40.45700  3.66400   51.19100  1.000 17.41000 ? 47  PRO A CG  1 
ATOM   373  C CD  . PRO A 1 46  ? 39.21200  2.91800   51.70200  1.000 18.54000 ? 47  PRO A CD  1 
ATOM   374  N N   . ARG A 1 47  ? 38.11400  6.79300   49.36200  1.000 15.44000 ? 48  ARG A N   1 
ATOM   375  C CA  . ARG A 1 47  ? 38.00400  7.29700   48.00000  1.000 18.93000 ? 48  ARG A CA  1 
ATOM   376  C C   . ARG A 1 47  ? 38.90900  8.50600   47.81100  1.000 17.30000 ? 48  ARG A C   1 
ATOM   377  O O   . ARG A 1 47  ? 38.85400  9.15700   46.76900  1.000 17.30000 ? 48  ARG A O   1 
ATOM   378  C CB  . ARG A 1 47  ? 36.54700  7.62400   47.63700  1.000 19.51000 ? 48  ARG A CB  1 
ATOM   379  C CG  . ARG A 1 47  ? 35.71800  6.31200   47.38500  1.000 21.94000 ? 48  ARG A CG  1 
ATOM   380  C CD  . ARG A 1 47  ? 36.30900  5.57900   46.12100  1.000 25.71000 ? 48  ARG A CD  1 
ATOM   381  N NE  . ARG A 1 47  ? 35.53600  4.42200   45.71700  1.000 23.51000 ? 48  ARG A NE  1 
ATOM   382  C CZ  . ARG A 1 47  ? 35.83600  3.19600   46.11500  1.000 27.94000 ? 48  ARG A CZ  1 
ATOM   383  N NH1 . ARG A 1 47  ? 36.85700  2.96800   46.94200  1.000 26.77000 ? 48  ARG A NH1 1 
ATOM   384  N NH2 . ARG A 1 47  ? 35.06600  2.18300   45.73700  1.000 30.68000 ? 48  ARG A NH2 1 
ATOM   385  N N   . ALA A 1 48  ? 39.72900  8.81800   48.79700  1.000 20.09000 ? 49  ALA A N   1 
ATOM   386  C CA  . ALA A 1 48  ? 40.65400  9.93100   48.65600  1.000 23.61000 ? 49  ALA A CA  1 
ATOM   387  C C   . ALA A 1 48  ? 41.92700  9.55900   49.38900  1.000 23.00000 ? 49  ALA A C   1 
ATOM   388  O O   . ALA A 1 48  ? 41.88800  8.84100   50.40600  1.000 18.52000 ? 49  ALA A O   1 
ATOM   389  C CB  . ALA A 1 48  ? 40.06300  11.25000  49.19600  1.000 19.94000 ? 49  ALA A CB  1 
ATOM   390  N N   . PRO A 1 49  ? 43.07500  10.04200  48.90100  1.000 22.51000 ? 50  PRO A N   1 
ATOM   391  C CA  . PRO A 1 49  ? 44.35500  9.59900   49.45000  1.000 25.61000 ? 50  PRO A CA  1 
ATOM   392  C C   . PRO A 1 49  ? 44.54100  9.99900   50.87900  1.000 24.51000 ? 50  PRO A C   1 
ATOM   393  O O   . PRO A 1 49  ? 45.18400  9.26200   51.62900  1.000 20.72000 ? 50  PRO A O   1 
ATOM   394  C CB  . PRO A 1 49  ? 45.38600  10.31100  48.55200  1.000 28.52000 ? 50  PRO A CB  1 
ATOM   395  C CG  . PRO A 1 49  ? 44.65700  10.71300  47.38000  1.000 37.89000 ? 50  PRO A CG  1 
ATOM   396  C CD  . PRO A 1 49  ? 43.24700  11.01200  47.82200  1.000 26.36000 ? 50  PRO A CD  1 
ATOM   397  N N   . TRP A 1 50  ? 43.96900  11.14600  51.28600  1.000 23.85000 ? 51  TRP A N   1 
ATOM   398  C CA  . TRP A 1 50  ? 44.16400  11.67900  52.61400  1.000 20.60000 ? 51  TRP A CA  1 
ATOM   399  C C   . TRP A 1 50  ? 43.31800  11.00800  53.70600  1.000 22.37000 ? 51  TRP A C   1 
ATOM   400  O O   . TRP A 1 50  ? 43.36700  11.48600  54.85300  1.000 20.39000 ? 51  TRP A O   1 
ATOM   401  C CB  . TRP A 1 50  ? 43.91500  13.19300  52.60900  1.000 22.87000 ? 51  TRP A CB  1 
ATOM   402  C CG  . TRP A 1 50  ? 42.76700  13.66800  51.76300  1.000 21.77000 ? 51  TRP A CG  1 
ATOM   403  C CD1 . TRP A 1 50  ? 42.78800  14.13300  50.44100  1.000 18.98000 ? 51  TRP A CD1 1 
ATOM   404  C CD2 . TRP A 1 50  ? 41.40800  13.71400  52.17500  1.000 20.06000 ? 51  TRP A CD2 1 
ATOM   405  N NE1 . TRP A 1 50  ? 41.51400  14.46500  50.04400  1.000 18.54000 ? 51  TRP A NE1 1 
ATOM   406  C CE2 . TRP A 1 50  ? 40.64700  14.21200  51.07800  1.000 18.43000 ? 51  TRP A CE2 1 
ATOM   407  C CE3 . TRP A 1 50  ? 40.75700  13.41700  53.37100  1.000 16.00000 ? 51  TRP A CE3 1 
ATOM   408  C CZ2 . TRP A 1 50  ? 39.25600  14.41700  51.16600  1.000 16.98000 ? 51  TRP A CZ2 1 
ATOM   409  C CZ3 . TRP A 1 50  ? 39.37500  13.60500  53.44500  1.000 17.28000 ? 51  TRP A CZ3 1 
ATOM   410  C CH2 . TRP A 1 50  ? 38.65400  14.08400  52.35900  1.000 14.46000 ? 51  TRP A CH2 1 
ATOM   411  N N   . VAL A 1 51  ? 42.56200  9.94300   53.40400  1.000 14.49000 ? 52  VAL A N   1 
ATOM   412  C CA  . VAL A 1 51  ? 42.08100  9.01500   54.41800  1.000 19.39000 ? 52  VAL A CA  1 
ATOM   413  C C   . VAL A 1 51  ? 42.62100  7.60400   54.20600  1.000 21.13000 ? 52  VAL A C   1 
ATOM   414  O O   . VAL A 1 51  ? 42.39600  6.72600   55.06900  1.000 17.32000 ? 52  VAL A O   1 
ATOM   415  C CB  . VAL A 1 51  ? 40.53100  8.96300   54.52000  1.000 20.09000 ? 52  VAL A CB  1 
ATOM   416  C CG1 . VAL A 1 51  ? 39.91700  10.25400  55.13400  1.000 16.35000 ? 52  VAL A CG1 1 
ATOM   417  C CG2 . VAL A 1 51  ? 39.83400  8.56700   53.12900  1.000 16.40000 ? 52  VAL A CG2 1 
ATOM   418  N N   . GLU A 1 52  ? 43.33300  7.34100   53.10000  1.000 20.89000 ? 53  GLU A N   1 
ATOM   419  C CA  . GLU A 1 52  ? 43.90700  5.99700   52.92200  1.000 24.52000 ? 53  GLU A CA  1 
ATOM   420  C C   . GLU A 1 52  ? 44.90700  5.68600   54.01700  1.000 24.28000 ? 53  GLU A C   1 
ATOM   421  O O   . GLU A 1 52  ? 45.20000  4.51500   54.27100  1.000 26.20000 ? 53  GLU A O   1 
ATOM   422  C CB  . GLU A 1 52  ? 44.65300  5.86300   51.57100  1.000 23.80000 ? 53  GLU A CB  1 
ATOM   423  C CG  . GLU A 1 52  ? 43.77400  5.83300   50.34800  1.000 29.61000 ? 53  GLU A CG  1 
ATOM   424  C CD  . GLU A 1 52  ? 44.57000  5.75900   49.04800  1.000 32.69000 ? 53  GLU A CD  1 
ATOM   425  O OE1 . GLU A 1 52  ? 45.79200  5.91900   49.07500  1.000 42.23000 ? 53  GLU A OE1 1 
ATOM   426  O OE2 . GLU A 1 52  ? 43.95200  5.70300   47.98600  1.000 41.03000 ? 53  GLU A OE2 1 
ATOM   427  N N   . GLN A 1 53  ? 45.46000  6.71000   54.63400  1.000 23.84000 ? 54  GLN A N   1 
ATOM   428  C CA  . GLN A 1 53  ? 46.47900  6.56900   55.65800  1.000 27.40000 ? 54  GLN A CA  1 
ATOM   429  C C   . GLN A 1 53  ? 45.92300  6.44100   57.06400  1.000 22.93000 ? 54  GLN A C   1 
ATOM   430  O O   . GLN A 1 53  ? 46.69400  6.21300   57.98200  1.000 19.73000 ? 54  GLN A O   1 
ATOM   431  C CB  . GLN A 1 53  ? 47.43500  7.76500   55.62100  1.000 39.01000 ? 54  GLN A CB  1 
ATOM   432  C CG  . GLN A 1 53  ? 48.71700  7.50800   54.81300  1.000 50.27000 ? 54  GLN A CG  1 
ATOM   433  C CD  . GLN A 1 53  ? 48.45400  6.81000   53.47500  1.000 52.96000 ? 54  GLN A CD  1 
ATOM   434  O OE1 . GLN A 1 53  ? 48.68400  5.59400   53.34400  1.000 57.86000 ? 54  GLN A OE1 1 
ATOM   435  N NE2 . GLN A 1 53  ? 47.96900  7.58300   52.46600  1.000 50.63000 ? 54  GLN A NE2 1 
ATOM   436  N N   . GLU A 1 54  ? 44.62400  6.60300   57.29100  1.000 19.86000 ? 55  GLU A N   1 
ATOM   437  C CA  . GLU A 1 54  ? 44.10400  6.24200   58.60200  1.000 18.31000 ? 55  GLU A CA  1 
ATOM   438  C C   . GLU A 1 54  ? 44.25000  4.72500   58.72800  1.000 22.41000 ? 55  GLU A C   1 
ATOM   439  O O   . GLU A 1 54  ? 44.24000  3.97200   57.72700  1.000 26.68000 ? 55  GLU A O   1 
ATOM   440  C CB  . GLU A 1 54  ? 42.62600  6.63600   58.71200  1.000 17.38000 ? 55  GLU A CB  1 
ATOM   441  C CG  . GLU A 1 54  ? 42.36300  8.11600   58.40900  1.000 16.40000 ? 55  GLU A CG  1 
ATOM   442  C CD  . GLU A 1 54  ? 42.81200  9.03100   59.52100  1.000 25.33000 ? 55  GLU A CD  1 
ATOM   443  O OE1 . GLU A 1 54  ? 43.15100  8.54000   60.61600  1.000 28.72000 ? 55  GLU A OE1 1 
ATOM   444  O OE2 . GLU A 1 54  ? 42.81300  10.23600  59.32200  1.000 27.10000 ? 55  GLU A OE2 1 
ATOM   445  N N   . GLY A 1 55  ? 44.39100  4.26200   59.92300  1.000 24.30000 ? 56  GLY A N   1 
ATOM   446  C CA  . GLY A 1 55  ? 44.77300  2.87000   60.04100  1.000 17.68000 ? 56  GLY A CA  1 
ATOM   447  C C   . GLY A 1 55  ? 43.59400  1.92200   60.13600  1.000 23.85000 ? 56  GLY A C   1 
ATOM   448  O O   . GLY A 1 55  ? 42.42400  2.30600   59.95200  1.000 17.48000 ? 56  GLY A O   1 
ATOM   449  N N   . PRO A 1 56  ? 43.89300  0.64700   60.42300  1.000 16.24000 ? 57  PRO A N   1 
ATOM   450  C CA  . PRO A 1 56  ? 42.83300  -0.37800  60.48200  1.000 15.76000 ? 57  PRO A CA  1 
ATOM   451  C C   . PRO A 1 56  ? 41.77900  -0.12100  61.53500  1.000 16.16000 ? 57  PRO A C   1 
ATOM   452  O O   . PRO A 1 56  ? 40.62300  -0.45100  61.29400  1.000 19.34000 ? 57  PRO A O   1 
ATOM   453  C CB  . PRO A 1 56  ? 43.60300  -1.68500  60.79400  1.000 16.71000 ? 57  PRO A CB  1 
ATOM   454  C CG  . PRO A 1 56  ? 45.03800  -1.36300  60.54600  1.000 21.42000 ? 57  PRO A CG  1 
ATOM   455  C CD  . PRO A 1 56  ? 45.23700  0.09800   60.63100  1.000 23.55000 ? 57  PRO A CD  1 
ATOM   456  N N   . GLU A 1 57  ? 42.13200  0.43100   62.68600  1.000 15.43000 ? 58  GLU A N   1 
ATOM   457  C CA  . GLU A 1 57  ? 41.12500  0.74800   63.71000  1.000 13.81000 ? 58  GLU A CA  1 
ATOM   458  C C   . GLU A 1 57  ? 40.09400  1.73300   63.16200  1.000 17.53000 ? 58  GLU A C   1 
ATOM   459  O O   . GLU A 1 57  ? 38.88100  1.55300   63.34600  1.000 19.37000 ? 58  GLU A O   1 
ATOM   460  C CB  . GLU A 1 57  ? 41.80500  1.31600   64.95100  1.000 19.56000 ? 58  GLU A CB  1 
ATOM   461  C CG  . GLU A 1 57  ? 40.88100  1.78000   66.07000  1.000 21.04000 ? 58  GLU A CG  1 
ATOM   462  C CD  . GLU A 1 57  ? 39.89700  0.65400   66.50400  1.000 33.10000 ? 58  GLU A CD  1 
ATOM   463  O OE1 . GLU A 1 57  ? 40.20400  -0.56700  66.36600  1.000 23.74000 ? 58  GLU A OE1 1 
ATOM   464  O OE2 . GLU A 1 57  ? 38.78900  0.98700   67.00600  1.000 37.58000 ? 58  GLU A OE2 1 
ATOM   465  N N   . TYR A 1 58  ? 40.56800  2.81800   62.55100  1.000 16.73000 ? 59  TYR A N   1 
ATOM   466  C CA  . TYR A 1 58  ? 39.65400  3.78100   61.92100  1.000 18.55000 ? 59  TYR A CA  1 
ATOM   467  C C   . TYR A 1 58  ? 38.72000  3.10100   60.92900  1.000 18.05000 ? 59  TYR A C   1 
ATOM   468  O O   . TYR A 1 58  ? 37.49000  3.25300   61.00100  1.000 15.73000 ? 59  TYR A O   1 
ATOM   469  C CB  . TYR A 1 58  ? 40.46100  4.86700   61.23400  1.000 13.62000 ? 59  TYR A CB  1 
ATOM   470  C CG  . TYR A 1 58  ? 39.67800  5.86400   60.38800  1.000 14.01000 ? 59  TYR A CG  1 
ATOM   471  C CD1 . TYR A 1 58  ? 39.39400  5.61000   59.05000  1.000 13.11000 ? 59  TYR A CD1 1 
ATOM   472  C CD2 . TYR A 1 58  ? 39.30800  7.10400   60.93900  1.000 12.92000 ? 59  TYR A CD2 1 
ATOM   473  C CE1 . TYR A 1 58  ? 38.65100  6.52800   58.24900  1.000 12.87000 ? 59  TYR A CE1 1 
ATOM   474  C CE2 . TYR A 1 58  ? 38.61500  8.04700   60.15700  1.000 16.03000 ? 59  TYR A CE2 1 
ATOM   475  C CZ  . TYR A 1 58  ? 38.29000  7.73100   58.79700  1.000 17.62000 ? 59  TYR A CZ  1 
ATOM   476  O OH  . TYR A 1 58  ? 37.60800  8.62800   58.00800  1.000 16.83000 ? 59  TYR A OH  1 
ATOM   477  N N   . TRP A 1 59  ? 39.27300  2.40300   59.96200  1.000 13.93000 ? 60  TRP A N   1 
ATOM   478  C CA  . TRP A 1 59  ? 38.47100  1.75800   58.93300  1.000 18.15000 ? 60  TRP A CA  1 
ATOM   479  C C   . TRP A 1 59  ? 37.51100  0.69100   59.44700  1.000 15.60000 ? 60  TRP A C   1 
ATOM   480  O O   . TRP A 1 59  ? 36.39600  0.63600   59.05300  1.000 19.13000 ? 60  TRP A O   1 
ATOM   481  C CB  . TRP A 1 59  ? 39.31400  1.30400   57.75500  1.000 16.77000 ? 60  TRP A CB  1 
ATOM   482  C CG  . TRP A 1 59  ? 39.72700  2.43500   56.96400  1.000 16.55000 ? 60  TRP A CG  1 
ATOM   483  C CD1 . TRP A 1 59  ? 40.95100  2.96500   56.87800  1.000 16.50000 ? 60  TRP A CD1 1 
ATOM   484  C CD2 . TRP A 1 59  ? 38.87800  3.25000   56.17200  1.000 15.53000 ? 60  TRP A CD2 1 
ATOM   485  N NE1 . TRP A 1 59  ? 40.93700  4.03800   56.06400  1.000 18.48000 ? 60  TRP A NE1 1 
ATOM   486  C CE2 . TRP A 1 59  ? 39.66600  4.23200   55.60600  1.000 15.52000 ? 60  TRP A CE2 1 
ATOM   487  C CE3 . TRP A 1 59  ? 37.52000  3.21000   55.84500  1.000 17.84000 ? 60  TRP A CE3 1 
ATOM   488  C CZ2 . TRP A 1 59  ? 39.14200  5.19200   54.75500  1.000 14.44000 ? 60  TRP A CZ2 1 
ATOM   489  C CZ3 . TRP A 1 59  ? 37.01100  4.17300   55.01700  1.000 14.25000 ? 60  TRP A CZ3 1 
ATOM   490  C CH2 . TRP A 1 59  ? 37.82300  5.13900   54.47500  1.000 14.79000 ? 60  TRP A CH2 1 
ATOM   491  N N   . ASP A 1 60  ? 37.94100  -0.11600  60.38300  1.000 15.25000 ? 61  ASP A N   1 
ATOM   492  C CA  . ASP A 1 60  ? 37.06700  -1.11600  60.94900  1.000 19.30000 ? 61  ASP A CA  1 
ATOM   493  C C   . ASP A 1 60  ? 35.91300  -0.48700  61.71500  1.000 17.56000 ? 61  ASP A C   1 
ATOM   494  O O   . ASP A 1 60  ? 34.81500  -0.94900  61.68000  1.000 16.59000 ? 61  ASP A O   1 
ATOM   495  C CB  . ASP A 1 60  ? 37.81900  -2.00700  61.89200  1.000 20.83000 ? 61  ASP A CB  1 
ATOM   496  C CG  . ASP A 1 60  ? 38.65400  -3.02700  61.19800  1.000 32.61000 ? 61  ASP A CG  1 
ATOM   497  O OD1 . ASP A 1 60  ? 38.61500  -3.15000  59.98900  1.000 31.69000 ? 61  ASP A OD1 1 
ATOM   498  O OD2 . ASP A 1 60  ? 39.35200  -3.71600  61.91100  1.000 36.91000 ? 61  ASP A OD2 1 
ATOM   499  N N   . ARG A 1 61  ? 36.20300  0.58500   62.40700  1.000 16.90000 ? 62  ARG A N   1 
ATOM   500  C CA  . ARG A 1 61  ? 35.19100  1.25600   63.13400  1.000 16.82000 ? 62  ARG A CA  1 
ATOM   501  C C   . ARG A 1 61  ? 34.12400  1.87400   62.21300  1.000 17.43000 ? 62  ARG A C   1 
ATOM   502  O O   . ARG A 1 61  ? 32.96600  1.79100   62.45900  1.000 14.28000 ? 62  ARG A O   1 
ATOM   503  C CB  . ARG A 1 61  ? 35.78700  2.29600   64.02200  1.000 19.27000 ? 62  ARG A CB  1 
ATOM   504  C CG  . ARG A 1 61  ? 34.79600  2.92200   64.94700  1.000 24.57000 ? 62  ARG A CG  1 
ATOM   505  C CD  . ARG A 1 61  ? 35.47800  3.73900   66.00800  1.000 36.67000 ? 62  ARG A CD  1 
ATOM   506  N NE  . ARG A 1 61  ? 34.51000  4.37600   66.84900  1.000 30.09000 ? 62  ARG A NE  1 
ATOM   507  C CZ  . ARG A 1 61  ? 34.78800  5.12200   67.88700  1.000 48.35000 ? 62  ARG A CZ  1 
ATOM   508  N NH1 . ARG A 1 61  ? 36.04000  5.37400   68.25200  1.000 33.63000 ? 62  ARG A NH1 1 
ATOM   509  N NH2 . ARG A 1 61  ? 33.79900  5.62600   68.58100  1.000 46.68000 ? 62  ARG A NH2 1 
ATOM   510  N N   . GLU A 1 62  ? 34.56800  2.51800   61.15500  1.000 16.58000 ? 63  GLU A N   1 
ATOM   511  C CA  . GLU A 1 62  ? 33.62900  3.09700   60.21600  1.000 15.38000 ? 63  GLU A CA  1 
ATOM   512  C C   . GLU A 1 62  ? 32.77400  1.98700   59.56300  1.000 13.53000 ? 63  GLU A C   1 
ATOM   513  O O   . GLU A 1 62  ? 31.61800  2.10900   59.43300  1.000 13.18000 ? 63  GLU A O   1 
ATOM   514  C CB  . GLU A 1 62  ? 34.33500  3.92400   59.16600  1.000 13.15000 ? 63  GLU A CB  1 
ATOM   515  C CG  . GLU A 1 62  ? 35.07700  5.11500   59.71500  1.000 12.25000 ? 63  GLU A CG  1 
ATOM   516  C CD  . GLU A 1 62  ? 34.20100  6.03500   60.50200  1.000 15.21000 ? 63  GLU A CD  1 
ATOM   517  O OE1 . GLU A 1 62  ? 33.50000  6.78200   59.89000  1.000 15.27000 ? 63  GLU A OE1 1 
ATOM   518  O OE2 . GLU A 1 62  ? 34.20900  5.98100   61.69200  1.000 14.38000 ? 63  GLU A OE2 1 
ATOM   519  N N   . THR A 1 63  ? 33.42200  0.92000   59.18900  1.000 13.14000 ? 64  THR A N   1 
ATOM   520  C CA  . THR A 1 63  ? 32.75500  -0.20300  58.58900  1.000 11.68000 ? 64  THR A CA  1 
ATOM   521  C C   . THR A 1 63  ? 31.58800  -0.72100  59.45900  1.000 14.63000 ? 64  THR A C   1 
ATOM   522  O O   . THR A 1 63  ? 30.52800  -0.98100  58.99900  1.000 15.51000 ? 64  THR A O   1 
ATOM   523  C CB  . THR A 1 63  ? 33.73200  -1.34700  58.29600  1.000 14.80000 ? 64  THR A CB  1 
ATOM   524  O OG1 . THR A 1 63  ? 34.56700  -1.02200  57.21400  1.000 14.71000 ? 64  THR A OG1 1 
ATOM   525  C CG2 . THR A 1 63  ? 32.96600  -2.63500  58.01100  1.000 17.16000 ? 64  THR A CG2 1 
ATOM   526  N N   . GLN A 1 64  ? 31.86800  -0.90000  60.72600  1.000 16.02000 ? 65  GLN A N   1 
ATOM   527  C CA  . GLN A 1 64  ? 30.91800  -1.35300  61.71900  1.000 17.46000 ? 65  GLN A CA  1 
ATOM   528  C C   . GLN A 1 64  ? 29.72100  -0.39900  61.77700  1.000 16.30000 ? 65  GLN A C   1 
ATOM   529  O O   . GLN A 1 64  ? 28.61900  -0.80700  61.79500  1.000 17.25000 ? 65  GLN A O   1 
ATOM   530  C CB  . GLN A 1 64  ? 31.63700  -1.47000  63.05300  1.000 17.26000 ? 65  GLN A CB  1 
ATOM   531  C CG  . GLN A 1 64  ? 30.79500  -1.85200  64.23800  1.000 28.73000 ? 65  GLN A CG  1 
ATOM   532  C CD  . GLN A 1 64  ? 31.63300  -2.20200  65.45800  1.000 43.59000 ? 65  GLN A CD  1 
ATOM   533  O OE1 . GLN A 1 64  ? 31.68000  -3.37800  65.86000  1.000 37.34000 ? 65  GLN A OE1 1 
ATOM   534  N NE2 . GLN A 1 64  ? 32.31100  -1.21300  66.03200  1.000 25.42000 ? 65  GLN A NE2 1 
ATOM   535  N N   . LYS A 1 65  ? 29.99400  0.88200   61.79700  1.000 14.33000 ? 66  LYS A N   1 
ATOM   536  C CA  . LYS A 1 65  ? 28.94900  1.88000   61.78900  1.000 15.48000 ? 66  LYS A CA  1 
ATOM   537  C C   . LYS A 1 65  ? 28.02400  1.68400   60.57700  1.000 12.32000 ? 66  LYS A C   1 
ATOM   538  O O   . LYS A 1 65  ? 26.83100  1.61500   60.71000  1.000 12.78000 ? 66  LYS A O   1 
ATOM   539  C CB  . LYS A 1 65  ? 29.54300  3.28900   61.72900  1.000 14.66000 ? 66  LYS A CB  1 
ATOM   540  C CG  . LYS A 1 65  ? 30.10500  3.86000   63.00400  1.000 16.53000 ? 66  LYS A CG  1 
ATOM   541  C CD  . LYS A 1 65  ? 30.80200  5.15800   62.67700  1.000 16.96000 ? 66  LYS A CD  1 
ATOM   542  C CE  . LYS A 1 65  ? 31.67900  5.68400   63.76500  1.000 19.95000 ? 66  LYS A CE  1 
ATOM   543  N NZ  . LYS A 1 65  ? 32.44300  6.86000   63.39000  1.000 16.83000 ? 66  LYS A NZ  1 
ATOM   544  N N   . TYR A 1 66  ? 28.63000  1.58300   59.40500  1.000 14.41000 ? 67  TYR A N   1 
ATOM   545  C CA  . TYR A 1 66  ? 27.80100  1.45500   58.19200  1.000 14.52000 ? 67  TYR A CA  1 
ATOM   546  C C   . TYR A 1 66  ? 27.03800  0.13700   58.19700  1.000 14.47000 ? 67  TYR A C   1 
ATOM   547  O O   . TYR A 1 66  ? 25.88600  0.06400   57.74000  1.000 14.56000 ? 67  TYR A O   1 
ATOM   548  C CB  . TYR A 1 66  ? 28.67000  1.52800   56.95500  1.000 11.90000 ? 67  TYR A CB  1 
ATOM   549  C CG  . TYR A 1 66  ? 29.33200  2.88000   56.74300  1.000 11.42000 ? 67  TYR A CG  1 
ATOM   550  C CD1 . TYR A 1 66  ? 28.57900  4.05300   56.78600  1.000 11.17000 ? 67  TYR A CD1 1 
ATOM   551  C CD2 . TYR A 1 66  ? 30.70500  2.97200   56.50500  1.000 12.02000 ? 67  TYR A CD2 1 
ATOM   552  C CE1 . TYR A 1 66  ? 29.17600  5.34000   56.59200  1.000 11.71000 ? 67  TYR A CE1 1 
ATOM   553  C CE2 . TYR A 1 66  ? 31.31500  4.23300   56.32100  1.000 13.28000 ? 67  TYR A CE2 1 
ATOM   554  C CZ  . TYR A 1 66  ? 30.52400  5.39700   56.32400  1.000 13.01000 ? 67  TYR A CZ  1 
ATOM   555  O OH  . TYR A 1 66  ? 31.09200  6.65900   56.14300  1.000 15.02000 ? 67  TYR A OH  1 
ATOM   556  N N   . LYS A 1 67  ? 27.68200  -0.94800  58.62800  1.000 14.71000 ? 68  LYS A N   1 
ATOM   557  C CA  . LYS A 1 67  ? 26.94700  -2.23200  58.63000  1.000 14.83000 ? 68  LYS A CA  1 
ATOM   558  C C   . LYS A 1 67  ? 25.76100  -2.20100  59.59500  1.000 13.11000 ? 68  LYS A C   1 
ATOM   559  O O   . LYS A 1 67  ? 24.64500  -2.68000  59.28400  1.000 14.99000 ? 68  LYS A O   1 
ATOM   560  C CB  . LYS A 1 67  ? 27.89300  -3.37500  59.00000  1.000 15.35000 ? 68  LYS A CB  1 
ATOM   561  C CG  . LYS A 1 67  ? 28.74800  -3.75900  57.77700  1.000 17.99000 ? 68  LYS A CG  1 
ATOM   562  C CD  . LYS A 1 67  ? 29.89300  -4.60800  58.23600  1.000 26.49000 ? 68  LYS A CD  1 
ATOM   563  C CE  . LYS A 1 67  ? 30.08500  -5.88600  57.47600  1.000 32.46000 ? 68  LYS A CE  1 
ATOM   564  N NZ  . LYS A 1 67  ? 31.38700  -6.43500  57.98000  1.000 32.30000 ? 68  LYS A NZ  1 
ATOM   565  N N   . ARG A 1 68  ? 25.96600  -1.63500  60.75900  1.000 14.29000 ? 69  ARG A N   1 
ATOM   566  C CA  . ARG A 1 68  ? 24.83900  -1.51800  61.66900  1.000 15.32000 ? 69  ARG A CA  1 
ATOM   567  C C   . ARG A 1 68  ? 23.78200  -0.54200  61.15600  1.000 15.53000 ? 69  ARG A C   1 
ATOM   568  O O   . ARG A 1 68  ? 22.58400  -0.75500  61.38800  1.000 14.74000 ? 69  ARG A O   1 
ATOM   569  C CB  . ARG A 1 68  ? 25.34900  -1.11500  63.05600  1.000 12.19000 ? 69  ARG A CB  1 
ATOM   570  C CG  . ARG A 1 68  ? 26.30600  -2.15800  63.58300  1.000 17.81000 ? 69  ARG A CG  1 
ATOM   571  C CD  . ARG A 1 68  ? 26.96500  -1.57200  64.83700  1.000 23.48000 ? 69  ARG A CD  1 
ATOM   572  N NE  . ARG A 1 68  ? 27.45800  -2.61300  65.72500  1.000 32.35000 ? 69  ARG A NE  1 
ATOM   573  C CZ  . ARG A 1 68  ? 28.28300  -2.37900  66.73300  1.000 45.37000 ? 69  ARG A CZ  1 
ATOM   574  N NH1 . ARG A 1 68  ? 28.62600  -1.13600  67.06700  1.000 32.71000 ? 69  ARG A NH1 1 
ATOM   575  N NH2 . ARG A 1 68  ? 28.76400  -3.41200  67.43400  1.000 48.67000 ? 69  ARG A NH2 1 
ATOM   576  N N   . GLN A 1 69  ? 24.19200  0.53700   60.49100  1.000 12.65000 ? 70  GLN A N   1 
ATOM   577  C CA  . GLN A 1 69  ? 23.19200  1.50200   60.02500  1.000 16.72000 ? 70  GLN A CA  1 
ATOM   578  C C   . GLN A 1 69  ? 22.38200  0.93900   58.85400  1.000 15.39000 ? 70  GLN A C   1 
ATOM   579  O O   . GLN A 1 69  ? 21.17900  1.22200   58.72900  1.000 15.67000 ? 70  GLN A O   1 
ATOM   580  C CB  . GLN A 1 69  ? 23.86300  2.81400   59.58300  1.000 16.33000 ? 70  GLN A CB  1 
ATOM   581  C CG  . GLN A 1 69  ? 22.85700  3.95600   59.29300  1.000 15.55000 ? 70  GLN A CG  1 
ATOM   582  C CD  . GLN A 1 69  ? 22.03900  4.29700   60.56500  1.000 21.10000 ? 70  GLN A CD  1 
ATOM   583  O OE1 . GLN A 1 69  ? 22.60300  4.64600   61.60900  1.000 19.15000 ? 70  GLN A OE1 1 
ATOM   584  N NE2 . GLN A 1 69  ? 20.73200  4.15900   60.48300  1.000 21.12000 ? 70  GLN A NE2 1 
ATOM   585  N N   . ALA A 1 70  ? 23.02200  0.14700   57.99100  1.000 13.88000 ? 71  ALA A N   1 
ATOM   586  C CA  . ALA A 1 70  ? 22.27200  -0.57000  56.96100  1.000 12.41000 ? 71  ALA A CA  1 
ATOM   587  C C   . ALA A 1 70  ? 21.18200  -1.45600  57.56300  1.000 15.92000 ? 71  ALA A C   1 
ATOM   588  O O   . ALA A 1 70  ? 20.04200  -1.48100  57.06700  1.000 13.90000 ? 71  ALA A O   1 
ATOM   589  C CB  . ALA A 1 70  ? 23.21400  -1.39600  56.07800  1.000 12.24000 ? 71  ALA A CB  1 
ATOM   590  N N   . GLN A 1 71  ? 21.52600  -2.27400  58.54400  1.000 12.68000 ? 72  GLN A N   1 
ATOM   591  C CA  . GLN A 1 71  ? 20.51100  -3.05100  59.23200  1.000 12.10000 ? 72  GLN A CA  1 
ATOM   592  C C   . GLN A 1 71  ? 19.40100  -2.20000  59.79500  1.000 14.63000 ? 72  GLN A C   1 
ATOM   593  O O   . GLN A 1 71  ? 18.21000  -2.59000  59.73500  1.000 11.81000 ? 72  GLN A O   1 
ATOM   594  C CB  . GLN A 1 71  ? 21.11800  -3.88800  60.35800  1.000 15.41000 ? 72  GLN A CB  1 
ATOM   595  C CG  . GLN A 1 71  ? 22.27700  -4.73800  59.93600  1.000 26.28000 ? 72  GLN A CG  1 
ATOM   596  C CD  . GLN A 1 71  ? 22.85300  -5.54700  61.09900  1.000 43.21000 ? 72  GLN A CD  1 
ATOM   597  O OE1 . GLN A 1 71  ? 24.05100  -5.45300  61.40000  1.000 49.45000 ? 72  GLN A OE1 1 
ATOM   598  N NE2 . GLN A 1 71  ? 21.96500  -6.20900  61.86100  1.000 49.97000 ? 72  GLN A NE2 1 
ATOM   599  N N   . ALA A 1 72  ? 19.76300  -1.10100  60.44200  1.000 15.36000 ? 73  ALA A N   1 
ATOM   600  C CA  . ALA A 1 72  ? 18.74200  -0.22900  61.03300  1.000 13.78000 ? 73  ALA A CA  1 
ATOM   601  C C   . ALA A 1 72  ? 17.84400  0.36200   59.96900  1.000 13.47000 ? 73  ALA A C   1 
ATOM   602  O O   . ALA A 1 72  ? 16.62500  0.44100   60.15400  1.000 13.76000 ? 73  ALA A O   1 
ATOM   603  C CB  . ALA A 1 72  ? 19.42700  0.89000   61.82800  1.000 12.95000 ? 73  ALA A CB  1 
ATOM   604  N N   . ASP A 1 73  ? 18.41400  0.77800   58.82900  1.000 14.37000 ? 74  ASP A N   1 
ATOM   605  C CA  . ASP A 1 73  ? 17.57700  1.37000   57.78000  1.000 10.43000 ? 74  ASP A CA  1 
ATOM   606  C C   . ASP A 1 73  ? 16.57800  0.37100   57.22300  1.000 11.58000 ? 74  ASP A C   1 
ATOM   607  O O   . ASP A 1 73  ? 15.49600  0.76100   56.75800  1.000 9.31000  ? 74  ASP A O   1 
ATOM   608  C CB  . ASP A 1 73  ? 18.44300  1.89100   56.63600  1.000 13.46000 ? 74  ASP A CB  1 
ATOM   609  C CG  . ASP A 1 73  ? 18.96800  3.30700   56.89900  1.000 20.91000 ? 74  ASP A CG  1 
ATOM   610  O OD1 . ASP A 1 73  ? 18.99700  3.77200   58.10400  1.000 19.08000 ? 74  ASP A OD1 1 
ATOM   611  O OD2 . ASP A 1 73  ? 19.36200  3.92900   55.89300  1.000 21.08000 ? 74  ASP A OD2 1 
ATOM   612  N N   . ARG A 1 74  ? 16.94800  -0.90000  57.18200  1.000 10.56000 ? 75  ARG A N   1 
ATOM   613  C CA  . ARG A 1 74  ? 16.00300  -1.89400  56.73400  1.000 11.75000 ? 75  ARG A CA  1 
ATOM   614  C C   . ARG A 1 74  ? 14.82300  -2.00700  57.68300  1.000 12.50000 ? 75  ARG A C   1 
ATOM   615  O O   . ARG A 1 74  ? 13.66600  -2.17300  57.23900  1.000 10.57000 ? 75  ARG A O   1 
ATOM   616  C CB  . ARG A 1 74  ? 16.72600  -3.23000  56.57300  1.000 14.92000 ? 75  ARG A CB  1 
ATOM   617  C CG  . ARG A 1 74  ? 17.55600  -3.20700  55.23800  1.000 16.11000 ? 75  ARG A CG  1 
ATOM   618  C CD  . ARG A 1 74  ? 18.51800  -4.36100  55.24500  1.000 18.94000 ? 75  ARG A CD  1 
ATOM   619  N NE  . ARG A 1 74  ? 19.42900  -4.24400  54.12000  1.000 15.46000 ? 75  ARG A NE  1 
ATOM   620  C CZ  . ARG A 1 74  ? 20.68800  -4.66700  54.19600  1.000 26.90000 ? 75  ARG A CZ  1 
ATOM   621  N NH1 . ARG A 1 74  ? 21.18000  -5.15800  55.34400  1.000 25.67000 ? 75  ARG A NH1 1 
ATOM   622  N NH2 . ARG A 1 74  ? 21.50400  -4.48500  53.14900  1.000 26.61000 ? 75  ARG A NH2 1 
ATOM   623  N N   . VAL A 1 75  ? 15.08700  -1.95700  58.99400  1.000 13.53000 ? 76  VAL A N   1 
ATOM   624  C CA  . VAL A 1 75  ? 14.00400  -1.92100  59.94600  1.000 13.82000 ? 76  VAL A CA  1 
ATOM   625  C C   . VAL A 1 75  ? 13.20600  -0.64600  59.80300  1.000 11.44000 ? 76  VAL A C   1 
ATOM   626  O O   . VAL A 1 75  ? 11.96300  -0.65300  59.86200  1.000 13.71000 ? 76  VAL A O   1 
ATOM   627  C CB  . VAL A 1 75  ? 14.49900  -2.06900  61.39000  1.000 13.11000 ? 76  VAL A CB  1 
ATOM   628  C CG1 . VAL A 1 75  ? 13.21900  -2.16500  62.27800  1.000 17.08000 ? 76  VAL A CG1 1 
ATOM   629  C CG2 . VAL A 1 75  ? 15.18300  -3.36200  61.53800  1.000 19.28000 ? 76  VAL A CG2 1 
ATOM   630  N N   . SER A 1 76  ? 13.90700  0.45900   59.63700  1.000 10.52000 ? 77  SER A N   1 
ATOM   631  C CA  . SER A 1 76  ? 13.23600  1.74100   59.50000  1.000 13.39000 ? 77  SER A CA  1 
ATOM   632  C C   . SER A 1 76  ? 12.29800  1.73800   58.28400  1.000 12.93000 ? 77  SER A C   1 
ATOM   633  O O   . SER A 1 76  ? 11.19800  2.31600   58.34200  1.000 10.39000 ? 77  SER A O   1 
ATOM   634  C CB  . SER A 1 76  ? 14.27400  2.83000   59.34100  1.000 9.71000  ? 77  SER A CB  1 
ATOM   635  O OG  . SER A 1 76  ? 14.95200  3.09600   60.59800  1.000 12.22000 ? 77  SER A OG  1 
ATOM   636  N N   . LEU A 1 77  ? 12.76100  1.19500   57.14000  1.000 10.39000 ? 78  LEU A N   1 
ATOM   637  C CA  . LEU A 1 77  ? 11.86600  1.13500   55.99200  1.000 11.83000 ? 78  LEU A CA  1 
ATOM   638  C C   . LEU A 1 77  ? 10.59000  0.37500   56.32300  1.000 12.74000 ? 78  LEU A C   1 
ATOM   639  O O   . LEU A 1 77  ? 9.49600   0.78700   55.91400  1.000 11.63000 ? 78  LEU A O   1 
ATOM   640  C CB  . LEU A 1 77  ? 12.56000  0.51500   54.76100  1.000 10.68000 ? 78  LEU A CB  1 
ATOM   641  C CG  . LEU A 1 77  ? 13.60300  1.46600   54.13100  1.000 11.03000 ? 78  LEU A CG  1 
ATOM   642  C CD1 . LEU A 1 77  ? 14.54100  0.69600   53.20800  1.000 12.72000 ? 78  LEU A CD1 1 
ATOM   643  C CD2 . LEU A 1 77  ? 12.88200  2.56400   53.35100  1.000 11.58000 ? 78  LEU A CD2 1 
ATOM   644  N N   A ARG A 1 78  ? 10.71100  -0.73400  57.06400  0.440 11.18000 ? 79  ARG A N   1 
ATOM   645  N N   B ARG A 1 78  ? 10.70200  -0.72800  57.07400  0.560 10.84000 ? 79  ARG A N   1 
ATOM   646  C CA  A ARG A 1 78  ? 9.54400   -1.47000  57.54200  0.440 13.69000 ? 79  ARG A CA  1 
ATOM   647  C CA  B ARG A 1 78  ? 9.50100   -1.43900  57.49500  0.560 13.69000 ? 79  ARG A CA  1 
ATOM   648  C C   A ARG A 1 78  ? 8.65700   -0.59500  58.42900  0.440 14.65000 ? 79  ARG A C   1 
ATOM   649  C C   B ARG A 1 78  ? 8.64100   -0.58400  58.42800  0.560 14.66000 ? 79  ARG A C   1 
ATOM   650  O O   A ARG A 1 78  ? 7.42200   -0.59700  58.29800  0.440 14.05000 ? 79  ARG A O   1 
ATOM   651  O O   B ARG A 1 78  ? 7.40300   -0.58100  58.31600  0.560 14.02000 ? 79  ARG A O   1 
ATOM   652  C CB  A ARG A 1 78  ? 10.01200  -2.71600  58.30600  0.440 14.33000 ? 79  ARG A CB  1 
ATOM   653  C CB  B ARG A 1 78  ? 9.87300   -2.77100  58.16300  0.560 14.43000 ? 79  ARG A CB  1 
ATOM   654  C CG  A ARG A 1 78  ? 8.90500   -3.69700  58.80900  0.440 19.46000 ? 79  ARG A CG  1 
ATOM   655  C CG  B ARG A 1 78  ? 8.60600   -3.61300  58.58100  0.560 18.33000 ? 79  ARG A CG  1 
ATOM   656  C CD  A ARG A 1 78  ? 9.57300   -5.02000  59.37900  0.440 22.58000 ? 79  ARG A CD  1 
ATOM   657  C CD  B ARG A 1 78  ? 8.95300   -5.03700  59.11600  0.560 24.21000 ? 79  ARG A CD  1 
ATOM   658  N NE  A ARG A 1 78  ? 10.35300  -5.66200  58.32900  0.440 25.25000 ? 79  ARG A NE  1 
ATOM   659  N NE  B ARG A 1 78  ? 9.75400   -5.74700  58.13000  0.560 24.17000 ? 79  ARG A NE  1 
ATOM   660  C CZ  A ARG A 1 78  ? 11.67800  -5.78700  58.29300  0.440 26.52000 ? 79  ARG A CZ  1 
ATOM   661  C CZ  B ARG A 1 78  ? 9.26300   -6.48400  57.14600  0.560 25.46000 ? 79  ARG A CZ  1 
ATOM   662  N NH1 A ARG A 1 78  ? 12.44300  -5.47900  59.33600  0.440 17.26000 ? 79  ARG A NH1 1 
ATOM   663  N NH1 B ARG A 1 78  ? 7.95700   -6.67700  57.01600  0.560 25.19000 ? 79  ARG A NH1 1 
ATOM   664  N NH2 A ARG A 1 78  ? 12.24900  -6.25100  57.18100  0.440 28.69000 ? 79  ARG A NH2 1 
ATOM   665  N NH2 B ARG A 1 78  ? 10.10000  -6.99200  56.23800  0.560 29.20000 ? 79  ARG A NH2 1 
ATOM   666  N N   . ASN A 1 79  ? 9.27100   0.12700   59.37300  1.000 13.70000 ? 80  ASN A N   1 
ATOM   667  C CA  . ASN A 1 79  ? 8.51200   0.98000   60.27900  1.000 12.45000 ? 80  ASN A CA  1 
ATOM   668  C C   . ASN A 1 79  ? 7.75100   2.03200   59.50400  1.000 12.96000 ? 80  ASN A C   1 
ATOM   669  O O   . ASN A 1 79  ? 6.56800   2.33000   59.80200  1.000 13.21000 ? 80  ASN A O   1 
ATOM   670  C CB  . ASN A 1 79  ? 9.45000   1.67600   61.26900  1.000 13.24000 ? 80  ASN A CB  1 
ATOM   671  C CG  . ASN A 1 79  ? 10.13400  0.69400   62.23100  1.000 16.65000 ? 80  ASN A CG  1 
ATOM   672  O OD1 . ASN A 1 79  ? 9.72000   -0.49000  62.33100  1.000 11.72000 ? 80  ASN A OD1 1 
ATOM   673  N ND2 . ASN A 1 79  ? 11.19800  1.16800   62.93300  1.000 11.97000 ? 80  ASN A ND2 1 
ATOM   674  N N   . LEU A 1 80  ? 8.42400   2.64100   58.52700  1.000 11.74000 ? 81  LEU A N   1 
ATOM   675  C CA  . LEU A 1 80  ? 7.76600   3.70100   57.76000  1.000 10.77000 ? 81  LEU A CA  1 
ATOM   676  C C   . LEU A 1 80  ? 6.56000   3.14700   56.99300  1.000 13.03000 ? 81  LEU A C   1 
ATOM   677  O O   . LEU A 1 80  ? 5.48900   3.76300   56.98400  1.000 14.20000 ? 81  LEU A O   1 
ATOM   678  C CB  . LEU A 1 80  ? 8.79800   4.34000   56.80600  1.000 12.92000 ? 81  LEU A CB  1 
ATOM   679  C CG  . LEU A 1 80  ? 9.82200   5.18100   57.54600  1.000 13.59000 ? 81  LEU A CG  1 
ATOM   680  C CD1 . LEU A 1 80  ? 11.10300  5.33300   56.72400  1.000 15.62000 ? 81  LEU A CD1 1 
ATOM   681  C CD2 . LEU A 1 80  ? 9.20000   6.56200   57.76500  1.000 14.63000 ? 81  LEU A CD2 1 
ATOM   682  N N   . ARG A 1 81  ? 6.70100   1.97100   56.36200  1.000 12.07000 ? 82  ARG A N   1 
ATOM   683  C CA  . ARG A 1 81  ? 5.50900   1.36800   55.73200  1.000 14.08000 ? 82  ARG A CA  1 
ATOM   684  C C   . ARG A 1 81  ? 4.39500   1.16000   56.75600  1.000 13.80000 ? 82  ARG A C   1 
ATOM   685  O O   . ARG A 1 81  ? 3.20200   1.32900   56.45400  1.000 13.80000 ? 82  ARG A O   1 
ATOM   686  C CB  . ARG A 1 81  ? 5.84400   0.01500   55.10100  1.000 15.68000 ? 82  ARG A CB  1 
ATOM   687  C CG  . ARG A 1 81  ? 6.57300   0.17900   53.72800  1.000 15.60000 ? 82  ARG A CG  1 
ATOM   688  C CD  . ARG A 1 81  ? 6.52900   -1.13300  52.92500  1.000 16.94000 ? 82  ARG A CD  1 
ATOM   689  N NE  . ARG A 1 81  ? 7.12400   -2.21600  53.68800  1.000 22.39000 ? 82  ARG A NE  1 
ATOM   690  C CZ  . ARG A 1 81  ? 6.44000   -3.13600  54.34500  1.000 23.79000 ? 82  ARG A CZ  1 
ATOM   691  N NH1 . ARG A 1 81  ? 5.09400   -3.12400  54.38300  1.000 30.38000 ? 82  ARG A NH1 1 
ATOM   692  N NH2 . ARG A 1 81  ? 7.11400   -4.09000  54.98900  1.000 23.28000 ? 82  ARG A NH2 1 
ATOM   693  N N   . GLY A 1 82  ? 4.76200   0.75800   57.95800  1.000 14.81000 ? 83  GLY A N   1 
ATOM   694  C CA  . GLY A 1 82  ? 3.75000   0.59200   59.00700  1.000 15.54000 ? 83  GLY A CA  1 
ATOM   695  C C   . GLY A 1 82  ? 3.01900   1.88400   59.29400  1.000 12.78000 ? 83  GLY A C   1 
ATOM   696  O O   . GLY A 1 82  ? 1.78400   1.90900   59.40400  1.000 14.34000 ? 83  GLY A O   1 
ATOM   697  N N   . TYR A 1 83  ? 3.75800   2.99200   59.40500  1.000 12.87000 ? 84  TYR A N   1 
ATOM   698  C CA  . TYR A 1 83  ? 3.09500   4.25700   59.76100  1.000 13.45000 ? 84  TYR A CA  1 
ATOM   699  C C   . TYR A 1 83  ? 2.06600   4.63700   58.71100  1.000 18.10000 ? 84  TYR A C   1 
ATOM   700  O O   . TYR A 1 83  ? 0.98200   5.15100   59.04600  1.000 12.78000 ? 84  TYR A O   1 
ATOM   701  C CB  . TYR A 1 83  ? 4.07800   5.43300   59.89700  1.000 14.46000 ? 84  TYR A CB  1 
ATOM   702  C CG  . TYR A 1 83  ? 5.20100   5.24600   60.90900  1.000 12.63000 ? 84  TYR A CG  1 
ATOM   703  C CD1 . TYR A 1 83  ? 5.03300   4.41500   62.01900  1.000 13.20000 ? 84  TYR A CD1 1 
ATOM   704  C CD2 . TYR A 1 83  ? 6.45000   5.87300   60.69400  1.000 11.68000 ? 84  TYR A CD2 1 
ATOM   705  C CE1 . TYR A 1 83  ? 6.08600   4.26200   62.96500  1.000 13.26000 ? 84  TYR A CE1 1 
ATOM   706  C CE2 . TYR A 1 83  ? 7.51100   5.75500   61.61100  1.000 10.13000 ? 84  TYR A CE2 1 
ATOM   707  C CZ  . TYR A 1 83  ? 7.31600   4.91700   62.74400  1.000 14.43000 ? 84  TYR A CZ  1 
ATOM   708  O OH  . TYR A 1 83  ? 8.38700   4.78400   63.62300  1.000 13.76000 ? 84  TYR A OH  1 
ATOM   709  N N   . TYR A 1 84  ? 2.41200   4.42900   57.42100  1.000 13.61000 ? 85  TYR A N   1 
ATOM   710  C CA  . TYR A 1 84  ? 1.53200   4.84800   56.34500  1.000 14.56000 ? 85  TYR A CA  1 
ATOM   711  C C   . TYR A 1 84  ? 0.58000   3.73800   55.89500  1.000 16.07000 ? 85  TYR A C   1 
ATOM   712  O O   . TYR A 1 84  ? -0.27100  3.97900   55.02900  1.000 17.78000 ? 85  TYR A O   1 
ATOM   713  C CB  . TYR A 1 84  ? 2.37800   5.33900   55.14900  1.000 9.10000  ? 85  TYR A CB  1 
ATOM   714  C CG  . TYR A 1 84  ? 3.19700   6.58800   55.37800  1.000 16.13000 ? 85  TYR A CG  1 
ATOM   715  C CD1 . TYR A 1 84  ? 2.59600   7.82100   55.42600  1.000 18.54000 ? 85  TYR A CD1 1 
ATOM   716  C CD2 . TYR A 1 84  ? 4.56400   6.52500   55.56800  1.000 11.62000 ? 85  TYR A CD2 1 
ATOM   717  C CE1 . TYR A 1 84  ? 3.32800   8.97700   55.62500  1.000 15.43000 ? 85  TYR A CE1 1 
ATOM   718  C CE2 . TYR A 1 84  ? 5.32400   7.68200   55.74500  1.000 13.18000 ? 85  TYR A CE2 1 
ATOM   719  C CZ  . TYR A 1 84  ? 4.68600   8.90500   55.77700  1.000 17.46000 ? 85  TYR A CZ  1 
ATOM   720  O OH  . TYR A 1 84  ? 5.40400   10.06400  55.96200  1.000 16.27000 ? 85  TYR A OH  1 
ATOM   721  N N   . ASN A 1 85  ? 0.71600   2.54700   56.45600  1.000 13.79000 ? 86  ASN A N   1 
ATOM   722  C CA  . ASN A 1 85  ? 0.06400   1.29300   56.00300  1.000 14.05000 ? 86  ASN A CA  1 
ATOM   723  C C   . ASN A 1 85  ? 0.28600   1.04500   54.52900  1.000 15.09000 ? 86  ASN A C   1 
ATOM   724  O O   . ASN A 1 85  ? -0.64400  0.66500   53.80200  1.000 11.08000 ? 86  ASN A O   1 
ATOM   725  C CB  . ASN A 1 85  ? -1.45600  1.20200   56.28600  1.000 19.20000 ? 86  ASN A CB  1 
ATOM   726  C CG  . ASN A 1 85  ? -1.93800  -0.31300  56.24100  1.000 25.63000 ? 86  ASN A CG  1 
ATOM   727  O OD1 . ASN A 1 85  ? -1.10700  -1.25000  56.38700  1.000 22.96000 ? 86  ASN A OD1 1 
ATOM   728  N ND2 . ASN A 1 85  ? -3.23300  -0.54800  55.98600  1.000 20.78000 ? 86  ASN A ND2 1 
ATOM   729  N N   . GLN A 1 86  ? 1.54600   1.20300   54.10500  1.000 12.49000 ? 87  GLN A N   1 
ATOM   730  C CA  . GLN A 1 86  ? 1.91900   0.89800   52.74000  1.000 15.97000 ? 87  GLN A CA  1 
ATOM   731  C C   . GLN A 1 86  ? 2.23400   -0.59100  52.59200  1.000 19.69000 ? 87  GLN A C   1 
ATOM   732  O O   . GLN A 1 86  ? 2.81900   -1.22400  53.48900  1.000 13.39000 ? 87  GLN A O   1 
ATOM   733  C CB  . GLN A 1 86  ? 3.14400   1.72700   52.32300  1.000 12.51000 ? 87  GLN A CB  1 
ATOM   734  C CG  . GLN A 1 86  ? 2.79500   3.17100   52.10600  1.000 10.59000 ? 87  GLN A CG  1 
ATOM   735  C CD  . GLN A 1 86  ? 4.02000   4.05800   52.06100  1.000 12.54000 ? 87  GLN A CD  1 
ATOM   736  O OE1 . GLN A 1 86  ? 5.03700   3.72600   52.60500  1.000 13.04000 ? 87  GLN A OE1 1 
ATOM   737  N NE2 . GLN A 1 86  ? 3.91300   5.17100   51.40500  1.000 14.47000 ? 87  GLN A NE2 1 
ATOM   738  N N   . SER A 1 87  ? 1.88300   -1.12400  51.43700  1.000 12.68000 ? 88  SER A N   1 
ATOM   739  C CA  . SER A 1 87  ? 2.12000   -2.52600  51.13100  1.000 15.17000 ? 88  SER A CA  1 
ATOM   740  C C   . SER A 1 87  ? 3.62000   -2.78700  50.92600  1.000 14.66000 ? 88  SER A C   1 
ATOM   741  O O   . SER A 1 87  ? 4.37400   -1.93900  50.41100  1.000 18.09000 ? 88  SER A O   1 
ATOM   742  C CB  . SER A 1 87  ? 1.36800   -2.89900  49.86100  1.000 18.42000 ? 88  SER A CB  1 
ATOM   743  O OG  . SER A 1 87  ? 1.82900   -4.08400  49.22800  1.000 21.83000 ? 88  SER A OG  1 
ATOM   744  N N   . GLU A 1 88  ? 4.03000   -3.99700  51.24800  1.000 14.65000 ? 89  GLU A N   1 
ATOM   745  C CA  . GLU A 1 88  ? 5.41200   -4.45300  50.96400  1.000 21.62000 ? 89  GLU A CA  1 
ATOM   746  C C   . GLU A 1 88  ? 5.71700   -4.59600  49.47900  1.000 20.81000 ? 89  GLU A C   1 
ATOM   747  O O   . GLU A 1 88  ? 6.88600   -4.77300  49.11800  1.000 16.09000 ? 89  GLU A O   1 
ATOM   748  C CB  . GLU A 1 88  ? 5.66700   -5.79500  51.67000  1.000 25.59000 ? 89  GLU A CB  1 
ATOM   749  C CG  . GLU A 1 88  ? 4.78800   -6.92900  51.08400  1.000 41.19000 ? 89  GLU A CG  1 
ATOM   750  C CD  . GLU A 1 88  ? 4.96400   -8.28500  51.81300  1.000 52.43000 ? 89  GLU A CD  1 
ATOM   751  O OE1 . GLU A 1 88  ? 5.31400   -8.28500  53.03600  1.000 54.04000 ? 89  GLU A OE1 1 
ATOM   752  O OE2 . GLU A 1 88  ? 4.78600   -9.32500  51.14400  1.000 49.54000 ? 89  GLU A OE2 1 
ATOM   753  N N   . ALA A 1 89  ? 4.70800   -4.54000  48.60600  1.000 17.59000 ? 90  ALA A N   1 
ATOM   754  C CA  . ALA A 1 89  ? 4.93200   -4.71300  47.15400  1.000 24.24000 ? 90  ALA A CA  1 
ATOM   755  C C   . ALA A 1 89  ? 5.54400   -3.48400  46.46800  1.000 22.50000 ? 90  ALA A C   1 
ATOM   756  O O   . ALA A 1 89  ? 6.04800   -3.59600  45.34500  1.000 15.68000 ? 90  ALA A O   1 
ATOM   757  C CB  . ALA A 1 89  ? 3.59500   -5.03200  46.44400  1.000 19.25000 ? 90  ALA A CB  1 
ATOM   758  N N   . GLY A 1 90  ? 5.48000   -2.31100  47.07800  1.000 19.03000 ? 91  GLY A N   1 
ATOM   759  C CA  . GLY A 1 90  ? 6.02500   -1.09100  46.48500  1.000 16.70000 ? 91  GLY A CA  1 
ATOM   760  C C   . GLY A 1 90  ? 7.42000   -0.74700  46.99100  1.000 12.99000 ? 91  GLY A C   1 
ATOM   761  O O   . GLY A 1 90  ? 7.74000   -0.95700  48.13300  1.000 14.78000 ? 91  GLY A O   1 
ATOM   762  N N   . SER A 1 91  ? 8.24200   -0.21300  46.11600  1.000 12.05000 ? 92  SER A N   1 
ATOM   763  C CA  . SER A 1 91  ? 9.59000   0.22600   46.47800  1.000 12.73000 ? 92  SER A CA  1 
ATOM   764  C C   . SER A 1 91  ? 9.51600   1.56300   47.21000  1.000 14.54000 ? 92  SER A C   1 
ATOM   765  O O   . SER A 1 91  ? 8.70600   2.42800   46.84900  1.000 12.04000 ? 92  SER A O   1 
ATOM   766  C CB  . SER A 1 91  ? 10.43300  0.41800   45.18500  1.000 18.16000 ? 92  SER A CB  1 
ATOM   767  O OG  . SER A 1 91  ? 11.73200  0.94600   45.55900  1.000 26.05000 ? 92  SER A OG  1 
ATOM   768  N N   . HIS A 1 92  ? 10.39900  1.77700   48.19300  1.000 11.37000 ? 93  HIS A N   1 
ATOM   769  C CA  . HIS A 1 92  ? 10.45500  3.08400   48.85700  1.000 10.63000 ? 93  HIS A CA  1 
ATOM   770  C C   . HIS A 1 92  ? 11.90100  3.45200   49.11300  1.000 11.78000 ? 93  HIS A C   1 
ATOM   771  O O   . HIS A 1 92  ? 12.77800  2.58300   49.19400  1.000 10.92000 ? 93  HIS A O   1 
ATOM   772  C CB  . HIS A 1 92  ? 9.64000   3.05800   50.21400  1.000 10.24000 ? 93  HIS A CB  1 
ATOM   773  C CG  . HIS A 1 92  ? 8.19200   2.75000   49.97600  1.000 12.40000 ? 93  HIS A CG  1 
ATOM   774  N ND1 . HIS A 1 92  ? 7.26200   3.73500   49.65600  1.000 9.91000  ? 93  HIS A ND1 1 
ATOM   775  C CD2 . HIS A 1 92  ? 7.52000   1.57600   49.96400  1.000 10.88000 ? 93  HIS A CD2 1 
ATOM   776  C CE1 . HIS A 1 92  ? 6.08800   3.16100   49.43200  1.000 11.51000 ? 93  HIS A CE1 1 
ATOM   777  N NE2 . HIS A 1 92  ? 6.22300   1.85400   49.60700  1.000 11.60000 ? 93  HIS A NE2 1 
ATOM   778  N N   . THR A 1 93  ? 12.11400  4.73900   49.30600  1.000 8.66000  ? 94  THR A N   1 
ATOM   779  C CA  . THR A 1 93  ? 13.42800  5.31000   49.54600  1.000 8.86000  ? 94  THR A CA  1 
ATOM   780  C C   . THR A 1 93  ? 13.48900  6.11100   50.84000  1.000 10.78000 ? 94  THR A C   1 
ATOM   781  O O   . THR A 1 93  ? 12.62400  6.95600   51.10400  1.000 11.06000 ? 94  THR A O   1 
ATOM   782  C CB  . THR A 1 93  ? 13.72600  6.22900   48.34100  1.000 9.05000  ? 94  THR A CB  1 
ATOM   783  O OG1 . THR A 1 93  ? 13.63900  5.44700   47.14000  1.000 12.56000 ? 94  THR A OG1 1 
ATOM   784  C CG2 . THR A 1 93  ? 15.05400  6.90700   48.43800  1.000 7.90000  ? 94  THR A CG2 1 
ATOM   785  N N   . LEU A 1 94  ? 14.58500  5.93200   51.59300  1.000 9.53000  ? 95  LEU A N   1 
ATOM   786  C CA  . LEU A 1 94  ? 14.85600  6.74900   52.78800  1.000 7.51000  ? 95  LEU A CA  1 
ATOM   787  C C   . LEU A 1 94  ? 16.17800  7.42000   52.51200  1.000 10.87000 ? 95  LEU A C   1 
ATOM   788  O O   . LEU A 1 94  ? 17.16300  6.71400   52.28900  1.000 9.74000  ? 95  LEU A O   1 
ATOM   789  C CB  . LEU A 1 94  ? 15.01000  5.85900   54.01300  1.000 7.59000  ? 95  LEU A CB  1 
ATOM   790  C CG  . LEU A 1 94  ? 15.41000  6.48400   55.37800  1.000 11.57000 ? 95  LEU A CG  1 
ATOM   791  C CD1 . LEU A 1 94  ? 14.28100  7.49500   55.72100  1.000 10.60000 ? 95  LEU A CD1 1 
ATOM   792  C CD2 . LEU A 1 94  ? 15.43100  5.40200   56.46200  1.000 15.34000 ? 95  LEU A CD2 1 
ATOM   793  N N   . GLN A 1 95  ? 16.21900  8.75300   52.59900  1.000 11.71000 ? 96  GLN A N   1 
ATOM   794  C CA  . GLN A 1 95  ? 17.46800  9.50400   52.43400  1.000 9.43000  ? 96  GLN A CA  1 
ATOM   795  C C   . GLN A 1 95  ? 17.76900  10.31900  53.67300  1.000 12.09000 ? 96  GLN A C   1 
ATOM   796  O O   . GLN A 1 95  ? 16.86000  10.83300  54.30800  1.000 8.79000  ? 96  GLN A O   1 
ATOM   797  C CB  . GLN A 1 95  ? 17.37800  10.45300  51.24500  1.000 8.14000  ? 96  GLN A CB  1 
ATOM   798  C CG  . GLN A 1 95  ? 17.35700  9.70300   49.89000  1.000 10.12000 ? 96  GLN A CG  1 
ATOM   799  C CD  . GLN A 1 95  ? 16.85200  10.65600  48.81700  1.000 11.54000 ? 96  GLN A CD  1 
ATOM   800  O OE1 . GLN A 1 95  ? 15.61800  10.69400  48.55000  1.000 14.38000 ? 96  GLN A OE1 1 
ATOM   801  N NE2 . GLN A 1 95  ? 17.77700  11.44900  48.20200  1.000 8.31000  ? 96  GLN A NE2 1 
ATOM   802  N N   . ARG A 1 96  ? 19.05700  10.47400  53.96600  1.000 7.58000  ? 97  ARG A N   1 
ATOM   803  C CA  . ARG A 1 96  ? 19.47200  11.27900  55.12100  1.000 11.65000 ? 97  ARG A CA  1 
ATOM   804  C C   . ARG A 1 96  ? 20.74000  12.00800  54.70500  1.000 12.46000 ? 97  ARG A C   1 
ATOM   805  O O   . ARG A 1 96  ? 21.63600  11.38000  54.13600  1.000 12.03000 ? 97  ARG A O   1 
ATOM   806  C CB  . ARG A 1 96  ? 19.76400  10.40500  56.37800  1.000 8.71000  ? 97  ARG A CB  1 
ATOM   807  C CG  . ARG A 1 96  ? 19.88500  11.28700  57.70400  1.000 10.15000 ? 97  ARG A CG  1 
ATOM   808  C CD  . ARG A 1 96  ? 19.92300  10.45200  59.01400  1.000 14.75000 ? 97  ARG A CD  1 
ATOM   809  N NE  . ARG A 1 96  ? 19.60100  11.29800  60.17200  1.000 14.86000 ? 97  ARG A NE  1 
ATOM   810  C CZ  . ARG A 1 96  ? 18.95600  10.88800  61.26100  1.000 17.15000 ? 97  ARG A CZ  1 
ATOM   811  N NH1 . ARG A 1 96  ? 18.61600  9.61000   61.43300  1.000 14.56000 ? 97  ARG A NH1 1 
ATOM   812  N NH2 . ARG A 1 96  ? 18.60600  11.79100  62.18500  1.000 15.19000 ? 97  ARG A NH2 1 
ATOM   813  N N   . MET A 1 97  ? 20.82400  13.31400  54.98700  1.000 11.39000 ? 98  MET A N   1 
ATOM   814  C CA  . MET A 1 97  ? 22.06300  14.06400  54.77400  1.000 11.06000 ? 98  MET A CA  1 
ATOM   815  C C   . MET A 1 97  ? 22.38000  14.85200  56.03700  1.000 10.51000 ? 98  MET A C   1 
ATOM   816  O O   . MET A 1 97  ? 21.48200  15.45800  56.63100  1.000 11.13000 ? 98  MET A O   1 
ATOM   817  C CB  . MET A 1 97  ? 21.94600  14.97100  53.55100  1.000 11.13000 ? 98  MET A CB  1 
ATOM   818  C CG  . MET A 1 97  ? 20.76000  15.91900  53.61600  1.000 15.35000 ? 98  MET A CG  1 
ATOM   819  S SD  . MET A 1 97  ? 20.73300  16.83000  51.98100  1.000 32.39000 ? 98  MET A SD  1 
ATOM   820  C CE  . MET A 1 97  ? 19.01500  17.36200  51.67500  1.000 24.01000 ? 98  MET A CE  1 
ATOM   821  N N   . TYR A 1 98  ? 23.64200  14.78800  56.46700  1.000 10.07000 ? 99  TYR A N   1 
ATOM   822  C CA  . TYR A 1 98  ? 24.04300  15.48300  57.66400  1.000 12.55000 ? 99  TYR A CA  1 
ATOM   823  C C   . TYR A 1 98  ? 25.47600  15.91700  57.47800  1.000 13.92000 ? 99  TYR A C   1 
ATOM   824  O O   . TYR A 1 98  ? 26.18800  15.42600  56.59600  1.000 11.80000 ? 99  TYR A O   1 
ATOM   825  C CB  . TYR A 1 98  ? 23.84300  14.63000  58.95900  1.000 13.75000 ? 99  TYR A CB  1 
ATOM   826  C CG  . TYR A 1 98  ? 24.75800  13.41700  59.03100  1.000 11.01000 ? 99  TYR A CG  1 
ATOM   827  C CD1 . TYR A 1 98  ? 26.05700  13.55400  59.54400  1.000 12.37000 ? 99  TYR A CD1 1 
ATOM   828  C CD2 . TYR A 1 98  ? 24.33400  12.14700  58.59400  1.000 13.97000 ? 99  TYR A CD2 1 
ATOM   829  C CE1 . TYR A 1 98  ? 26.91700  12.48200  59.58600  1.000 11.32000 ? 99  TYR A CE1 1 
ATOM   830  C CE2 . TYR A 1 98  ? 25.21200  11.03700  58.64400  1.000 12.97000 ? 99  TYR A CE2 1 
ATOM   831  C CZ  . TYR A 1 98  ? 26.50300  11.24200  59.15800  1.000 13.51000 ? 99  TYR A CZ  1 
ATOM   832  O OH  . TYR A 1 98  ? 27.40400  10.17000  59.24500  1.000 11.33000 ? 99  TYR A OH  1 
ATOM   833  N N   . GLY A 1 99  ? 25.89000  16.88100  58.28300  1.000 15.93000 ? 100 GLY A N   1 
ATOM   834  C CA  . GLY A 1 99  ? 27.22800  17.40500  58.10700  1.000 13.05000 ? 100 GLY A CA  1 
ATOM   835  C C   . GLY A 1 99  ? 27.41800  18.71500  58.84100  1.000 14.79000 ? 100 GLY A C   1 
ATOM   836  O O   . GLY A 1 99  ? 26.52800  19.19700  59.56200  1.000 10.87000 ? 100 GLY A O   1 
ATOM   837  N N   . CYS A 1 100 ? 28.62300  19.27000  58.66100  1.000 13.77000 ? 101 CYS A N   1 
ATOM   838  C CA  . CYS A 1 100 ? 28.99400  20.53400  59.32100  1.000 14.67000 ? 101 CYS A CA  1 
ATOM   839  C C   . CYS A 1 100 ? 29.67500  21.47700  58.34000  1.000 17.33000 ? 101 CYS A C   1 
ATOM   840  O O   . CYS A 1 100 ? 30.45200  21.03900  57.48800  1.000 15.32000 ? 101 CYS A O   1 
ATOM   841  C CB  . CYS A 1 100 ? 29.88900  20.30500  60.54900  1.000 14.07000 ? 101 CYS A CB  1 
ATOM   842  S SG  . CYS A 1 100 ? 31.28800  19.21500  60.32100  1.000 20.29000 ? 101 CYS A SG  1 
ATOM   843  N N   . ASP A 1 101 ? 29.35000  22.76500  58.45000  1.000 16.89000 ? 102 ASP A N   1 
ATOM   844  C CA  . ASP A 1 101 ? 30.02200  23.82500  57.71000  1.000 19.96000 ? 102 ASP A CA  1 
ATOM   845  C C   . ASP A 1 101 ? 30.93600  24.60100  58.64500  1.000 22.18000 ? 102 ASP A C   1 
ATOM   846  O O   . ASP A 1 101 ? 30.52600  24.94600  59.75000  1.000 23.50000 ? 102 ASP A O   1 
ATOM   847  C CB  . ASP A 1 101 ? 29.01600  24.81700  57.12400  1.000 23.17000 ? 102 ASP A CB  1 
ATOM   848  C CG  . ASP A 1 101 ? 28.06400  24.17900  56.15600  1.000 20.65000 ? 102 ASP A CG  1 
ATOM   849  O OD1 . ASP A 1 101 ? 28.37000  23.11700  55.54300  1.000 19.24000 ? 102 ASP A OD1 1 
ATOM   850  O OD2 . ASP A 1 101 ? 26.99000  24.76000  56.00200  1.000 22.81000 ? 102 ASP A OD2 1 
ATOM   851  N N   . LEU A 1 102 ? 32.14300  24.92600  58.16800  1.000 22.10000 ? 103 LEU A N   1 
ATOM   852  C CA  . LEU A 1 102 ? 33.13400  25.75700  58.85300  1.000 26.69000 ? 103 LEU A CA  1 
ATOM   853  C C   . LEU A 1 102 ? 33.23100  27.11400  58.16000  1.000 28.18000 ? 103 LEU A C   1 
ATOM   854  O O   . LEU A 1 102 ? 33.18200  27.18500  56.91700  1.000 28.84000 ? 103 LEU A O   1 
ATOM   855  C CB  . LEU A 1 102 ? 34.51800  25.13800  58.77200  1.000 26.10000 ? 103 LEU A CB  1 
ATOM   856  C CG  . LEU A 1 102 ? 34.73800  23.90300  59.59000  1.000 30.83000 ? 103 LEU A CG  1 
ATOM   857  C CD1 . LEU A 1 102 ? 36.20700  23.75800  59.67000  1.000 23.94000 ? 103 LEU A CD1 1 
ATOM   858  C CD2 . LEU A 1 102 ? 34.04900  24.05200  60.98600  1.000 29.47000 ? 103 LEU A CD2 1 
ATOM   859  N N   . GLY A 1 103 ? 33.40600  28.18900  58.94800  1.000 35.41000 ? 104 GLY A N   1 
ATOM   860  C CA  . GLY A 1 103 ? 33.64900  29.50500  58.37100  1.000 33.09000 ? 104 GLY A CA  1 
ATOM   861  C C   . GLY A 1 103 ? 35.13300  29.74600  58.13300  1.000 37.51000 ? 104 GLY A C   1 
ATOM   862  O O   . GLY A 1 103 ? 35.97200  28.91100  58.51000  1.000 31.72000 ? 104 GLY A O   1 
ATOM   863  N N   . PRO A 1 104 ? 35.49000  30.89000  57.51600  1.000 37.85000 ? 105 PRO A N   1 
ATOM   864  C CA  . PRO A 1 104 ? 36.91900  31.21400  57.33200  1.000 39.18000 ? 105 PRO A CA  1 
ATOM   865  C C   . PRO A 1 104 ? 37.75500  31.13800  58.60600  1.000 41.94000 ? 105 PRO A C   1 
ATOM   866  O O   . PRO A 1 104 ? 38.98000  30.92000  58.51200  1.000 36.25000 ? 105 PRO A O   1 
ATOM   867  C CB  . PRO A 1 104 ? 36.89100  32.64300  56.76700  1.000 39.23000 ? 105 PRO A CB  1 
ATOM   868  C CG  . PRO A 1 104 ? 35.46500  33.11200  56.88700  1.000 39.75000 ? 105 PRO A CG  1 
ATOM   869  C CD  . PRO A 1 104 ? 34.61200  31.88900  56.89000  1.000 38.75000 ? 105 PRO A CD  1 
ATOM   870  N N   . ASP A 1 105 ? 37.14600  31.25600  59.80800  1.000 37.38000 ? 106 ASP A N   1 
ATOM   871  C CA  . ASP A 1 105 ? 37.89500  31.07000  61.06400  1.000 37.48000 ? 106 ASP A CA  1 
ATOM   872  C C   . ASP A 1 105 ? 38.12200  29.60400  61.48000  1.000 42.63000 ? 106 ASP A C   1 
ATOM   873  O O   . ASP A 1 105 ? 38.60200  29.39300  62.60600  1.000 41.09000 ? 106 ASP A O   1 
ATOM   874  C CB  . ASP A 1 105 ? 37.20500  31.77800  62.23800  1.000 33.93000 ? 106 ASP A CB  1 
ATOM   875  C CG  . ASP A 1 105 ? 35.71900  31.39800  62.37500  1.000 44.53000 ? 106 ASP A CG  1 
ATOM   876  O OD1 . ASP A 1 105 ? 35.23200  30.57300  61.55600  1.000 41.13000 ? 106 ASP A OD1 1 
ATOM   877  O OD2 . ASP A 1 105 ? 35.05200  31.89500  63.33000  1.000 41.16000 ? 106 ASP A OD2 1 
ATOM   878  N N   . GLY A 1 106 ? 37.79500  28.59600  60.65100  1.000 39.15000 ? 107 GLY A N   1 
ATOM   879  C CA  . GLY A 1 106 ? 37.83700  27.20500  61.11900  1.000 34.12000 ? 107 GLY A CA  1 
ATOM   880  C C   . GLY A 1 106 ? 36.86100  26.82700  62.23400  1.000 34.06000 ? 107 GLY A C   1 
ATOM   881  O O   . GLY A 1 106 ? 37.03500  25.78400  62.86500  1.000 36.60000 ? 107 GLY A O   1 
ATOM   882  N N   . ARG A 1 107 ? 35.83600  27.62800  62.49200  1.000 32.43000 ? 108 ARG A N   1 
ATOM   883  C CA  . ARG A 1 107 ? 34.85700  27.38400  63.54300  1.000 38.22000 ? 108 ARG A CA  1 
ATOM   884  C C   . ARG A 1 107 ? 33.51800  26.93100  62.93800  1.000 29.47000 ? 108 ARG A C   1 
ATOM   885  O O   . ARG A 1 107 ? 33.14300  27.32300  61.82000  1.000 33.84000 ? 108 ARG A O   1 
ATOM   886  C CB  . ARG A 1 107 ? 34.66000  28.66200  64.40000  1.000 35.46000 ? 108 ARG A CB  1 
ATOM   887  C CG  . ARG A 1 107 ? 35.58900  28.76100  65.60100  0.000 38.99000 ? 108 ARG A CG  1 
ATOM   888  C CD  . ARG A 1 107 ? 35.42300  30.07400  66.37400  0.000 41.13000 ? 108 ARG A CD  1 
ATOM   889  N NE  . ARG A 1 107 ? 34.10500  30.22100  66.98300  0.000 42.15000 ? 108 ARG A NE  1 
ATOM   890  C CZ  . ARG A 1 107 ? 33.06100  30.79700  66.40200  0.000 41.82000 ? 108 ARG A CZ  1 
ATOM   891  N NH1 . ARG A 1 107 ? 33.14900  31.33900  65.19700  0.000 41.52000 ? 108 ARG A NH1 1 
ATOM   892  N NH2 . ARG A 1 107 ? 31.89900  30.83800  67.04800  0.000 42.14000 ? 108 ARG A NH2 1 
ATOM   893  N N   . LEU A 1 108 ? 32.81000  26.07400  63.67000  1.000 28.02000 ? 109 LEU A N   1 
ATOM   894  C CA  . LEU A 1 108 ? 31.47500  25.67000  63.24800  1.000 28.52000 ? 109 LEU A CA  1 
ATOM   895  C C   . LEU A 1 108 ? 30.62500  26.88300  62.95400  1.000 28.50000 ? 109 LEU A C   1 
ATOM   896  O O   . LEU A 1 108 ? 30.41600  27.75000  63.80700  1.000 34.05000 ? 109 LEU A O   1 
ATOM   897  C CB  . LEU A 1 108 ? 30.80000  24.82500  64.32300  1.000 23.19000 ? 109 LEU A CB  1 
ATOM   898  C CG  . LEU A 1 108 ? 29.36900  24.42200  64.01800  1.000 24.49000 ? 109 LEU A CG  1 
ATOM   899  C CD1 . LEU A 1 108 ? 29.34800  23.48300  62.81500  1.000 31.06000 ? 109 LEU A CD1 1 
ATOM   900  C CD2 . LEU A 1 108 ? 28.75000  23.73500  65.21100  1.000 31.84000 ? 109 LEU A CD2 1 
ATOM   901  N N   . LEU A 1 109 ? 30.15600  26.94700  61.73200  1.000 27.54000 ? 110 LEU A N   1 
ATOM   902  C CA  . LEU A 1 109 ? 29.15000  27.88200  61.28800  1.000 24.10000 ? 110 LEU A CA  1 
ATOM   903  C C   . LEU A 1 109 ? 27.74700  27.30900  61.39700  1.000 31.48000 ? 110 LEU A C   1 
ATOM   904  O O   . LEU A 1 109 ? 26.83100  28.03000  61.78100  1.000 28.51000 ? 110 LEU A O   1 
ATOM   905  C CB  . LEU A 1 109 ? 29.46500  28.25000  59.85400  1.000 26.05000 ? 110 LEU A CB  1 
ATOM   906  C CG  . LEU A 1 109 ? 28.76000  29.36800  59.14400  1.000 38.49000 ? 110 LEU A CG  1 
ATOM   907  C CD1 . LEU A 1 109 ? 29.16700  30.67200  59.81900  1.000 38.56000 ? 110 LEU A CD1 1 
ATOM   908  C CD2 . LEU A 1 109 ? 29.26300  29.27700  57.70200  1.000 37.49000 ? 110 LEU A CD2 1 
ATOM   909  N N   . ARG A 1 110 ? 27.53600  26.04300  61.00700  1.000 27.21000 ? 111 ARG A N   1 
ATOM   910  C CA  . ARG A 1 110 ? 26.24800  25.38300  61.24800  1.000 20.11000 ? 111 ARG A CA  1 
ATOM   911  C C   . ARG A 1 110 ? 26.40300  23.86900  61.06900  1.000 20.33000 ? 111 ARG A C   1 
ATOM   912  O O   . ARG A 1 110 ? 27.23900  23.40700  60.28800  1.000 27.26000 ? 111 ARG A O   1 
ATOM   913  C CB  . ARG A 1 110 ? 25.15500  25.95200  60.34000  1.000 32.13000 ? 111 ARG A CB  1 
ATOM   914  C CG  . ARG A 1 110 ? 25.07100  25.44200  58.91700  1.000 30.73000 ? 111 ARG A CG  1 
ATOM   915  C CD  . ARG A 1 110 ? 23.55900  25.38000  58.39700  1.000 47.57000 ? 111 ARG A CD  1 
ATOM   916  N NE  . ARG A 1 110 ? 23.43600  24.84600  57.03000  1.000 61.41000 ? 111 ARG A NE  1 
ATOM   917  C CZ  . ARG A 1 110 ? 22.38500  24.18900  56.53200  1.000 52.48000 ? 111 ARG A CZ  1 
ATOM   918  N NH1 . ARG A 1 110 ? 21.20500  24.18000  57.15100  1.000 49.50000 ? 111 ARG A NH1 1 
ATOM   919  N NH2 . ARG A 1 110 ? 22.51700  23.53700  55.37400  1.000 48.91000 ? 111 ARG A NH2 1 
ATOM   920  N N   . GLY A 1 111 ? 25.63900  23.11900  61.85600  1.000 20.52000 ? 112 GLY A N   1 
ATOM   921  C CA  . GLY A 1 111 ? 25.51800  21.67600  61.70000  1.000 20.32000 ? 112 GLY A CA  1 
ATOM   922  C C   . GLY A 1 111 ? 24.12200  21.38400  61.18100  1.000 20.18000 ? 112 GLY A C   1 
ATOM   923  O O   . GLY A 1 111 ? 23.22100  22.21000  61.38900  1.000 16.57000 ? 112 GLY A O   1 
ATOM   924  N N   . TYR A 1 112 ? 23.91000  20.25400  60.48300  1.000 15.75000 ? 113 TYR A N   1 
ATOM   925  C CA  . TYR A 1 112 ? 22.56600  20.02500  59.98200  1.000 18.13000 ? 113 TYR A CA  1 
ATOM   926  C C   . TYR A 1 112 ? 22.33400  18.53000  59.88200  1.000 15.02000 ? 113 TYR A C   1 
ATOM   927  O O   . TYR A 1 112 ? 23.27900  17.72500  59.84600  1.000 12.21000 ? 113 TYR A O   1 
ATOM   928  C CB  . TYR A 1 112 ? 22.33600  20.62700  58.58800  1.000 21.35000 ? 113 TYR A CB  1 
ATOM   929  C CG  . TYR A 1 112 ? 23.56700  20.65600  57.77400  1.000 24.16000 ? 113 TYR A CG  1 
ATOM   930  C CD1 . TYR A 1 112 ? 23.93700  19.58100  56.95600  1.000 28.09000 ? 113 TYR A CD1 1 
ATOM   931  C CD2 . TYR A 1 112 ? 24.47200  21.71500  57.93500  1.000 36.18000 ? 113 TYR A CD2 1 
ATOM   932  C CE1 . TYR A 1 112 ? 25.16000  19.63400  56.22900  1.000 26.62000 ? 113 TYR A CE1 1 
ATOM   933  C CE2 . TYR A 1 112 ? 25.65700  21.75500  57.25200  1.000 34.62000 ? 113 TYR A CE2 1 
ATOM   934  C CZ  . TYR A 1 112 ? 25.99400  20.71700  56.41000  1.000 21.68000 ? 113 TYR A CZ  1 
ATOM   935  O OH  . TYR A 1 112 ? 27.21500  20.88600  55.76500  1.000 30.60000 ? 113 TYR A OH  1 
ATOM   936  N N   . ASP A 1 113 ? 21.05100  18.18700  59.84200  1.000 14.69000 ? 114 ASP A N   1 
ATOM   937  C CA  . ASP A 1 113 ? 20.63100  16.80900  59.62800  1.000 15.24000 ? 114 ASP A CA  1 
ATOM   938  C C   . ASP A 1 113 ? 19.21500  16.83200  59.09400  1.000 15.34000 ? 114 ASP A C   1 
ATOM   939  O O   . ASP A 1 113 ? 18.32900  17.43900  59.71100  1.000 16.27000 ? 114 ASP A O   1 
ATOM   940  C CB  . ASP A 1 113 ? 20.65600  16.00300  60.93900  1.000 14.51000 ? 114 ASP A CB  1 
ATOM   941  C CG  . ASP A 1 113 ? 20.02700  14.64800  60.77100  1.000 18.76000 ? 114 ASP A CG  1 
ATOM   942  O OD1 . ASP A 1 113 ? 20.58300  13.83300  59.97700  1.000 15.71000 ? 114 ASP A OD1 1 
ATOM   943  O OD2 . ASP A 1 113 ? 18.97400  14.38400  61.39000  1.000 16.41000 ? 114 ASP A OD2 1 
ATOM   944  N N   . GLN A 1 114 ? 18.97700  16.13300  58.00700  1.000 11.32000 ? 115 GLN A N   1 
ATOM   945  C CA  . GLN A 1 114 ? 17.65100  16.17900  57.40300  1.000 15.31000 ? 115 GLN A CA  1 
ATOM   946  C C   . GLN A 1 114 ? 17.41100  14.82900  56.78000  1.000 12.28000 ? 115 GLN A C   1 
ATOM   947  O O   . GLN A 1 114 ? 18.35000  14.23100  56.24700  1.000 11.83000 ? 115 GLN A O   1 
ATOM   948  C CB  . GLN A 1 114 ? 17.51500  17.24300  56.31300  1.000 18.65000 ? 115 GLN A CB  1 
ATOM   949  C CG  . GLN A 1 114 ? 18.18600  18.51400  56.62500  1.000 34.25000 ? 115 GLN A CG  1 
ATOM   950  C CD  . GLN A 1 114 ? 18.43500  19.36500  55.38100  1.000 36.93000 ? 115 GLN A CD  1 
ATOM   951  O OE1 . GLN A 1 114 ? 19.47600  19.99900  55.27800  1.000 40.95000 ? 115 GLN A OE1 1 
ATOM   952  N NE2 . GLN A 1 114 ? 17.50300  19.36300  54.44600  1.000 41.18000 ? 115 GLN A NE2 1 
ATOM   953  N N   . SER A 1 115 ? 16.15700  14.39000  56.81800  1.000 10.33000 ? 116 SER A N   1 
ATOM   954  C CA  . SER A 1 115 ? 15.75700  13.11900  56.22200  1.000 11.63000 ? 116 SER A CA  1 
ATOM   955  C C   . SER A 1 115 ? 14.58400  13.32500  55.27100  1.000 11.26000 ? 116 SER A C   1 
ATOM   956  O O   . SER A 1 115 ? 13.75200  14.22700  55.46500  1.000 15.52000 ? 116 SER A O   1 
ATOM   957  C CB  . SER A 1 115 ? 15.31000  12.08000  57.28800  1.000 8.96000  ? 116 SER A CB  1 
ATOM   958  O OG  . SER A 1 115 ? 16.37600  11.79800  58.19300  1.000 11.07000 ? 116 SER A OG  1 
ATOM   959  N N   . ALA A 1 116 ? 14.48700  12.43900  54.27900  1.000 10.48000 ? 117 ALA A N   1 
ATOM   960  C CA  . ALA A 1 116 ? 13.39200  12.44500  53.30500  1.000 12.02000 ? 117 ALA A CA  1 
ATOM   961  C C   . ALA A 1 116 ? 12.91100  11.02800  53.06600  1.000 13.55000 ? 117 ALA A C   1 
ATOM   962  O O   . ALA A 1 116 ? 13.73500  10.10100  53.02500  1.000 10.97000 ? 117 ALA A O   1 
ATOM   963  C CB  . ALA A 1 116 ? 13.81600  13.04200  51.92200  1.000 10.04000 ? 117 ALA A CB  1 
ATOM   964  N N   . TYR A 1 117 ? 11.59800  10.87000  52.88000  1.000 9.06000  ? 118 TYR A N   1 
ATOM   965  C CA  . TYR A 1 117 ? 10.99100  9.57100   52.60400  1.000 10.31000 ? 118 TYR A CA  1 
ATOM   966  C C   . TYR A 1 117 ? 10.31400  9.68100   51.25200  1.000 11.17000 ? 118 TYR A C   1 
ATOM   967  O O   . TYR A 1 117 ? 9.50100   10.58500  51.04300  1.000 10.94000 ? 118 TYR A O   1 
ATOM   968  C CB  . TYR A 1 117 ? 10.00900  9.15500   53.70500  1.000 9.89000  ? 118 TYR A CB  1 
ATOM   969  C CG  . TYR A 1 117 ? 9.36200   7.77900   53.49600  1.000 10.28000 ? 118 TYR A CG  1 
ATOM   970  C CD1 . TYR A 1 117 ? 10.13900  6.61700   53.36800  1.000 11.79000 ? 118 TYR A CD1 1 
ATOM   971  C CD2 . TYR A 1 117 ? 7.98600   7.65800   53.39900  1.000 11.99000 ? 118 TYR A CD2 1 
ATOM   972  C CE1 . TYR A 1 117 ? 9.56000   5.33800   53.14900  1.000 13.83000 ? 118 TYR A CE1 1 
ATOM   973  C CE2 . TYR A 1 117 ? 7.35800   6.38500   53.16900  1.000 8.98000  ? 118 TYR A CE2 1 
ATOM   974  C CZ  . TYR A 1 117 ? 8.19500   5.21900   53.09100  1.000 12.18000 ? 118 TYR A CZ  1 
ATOM   975  O OH  . TYR A 1 117 ? 7.64800   3.97400   52.91100  1.000 12.65000 ? 118 TYR A OH  1 
ATOM   976  N N   . ASP A 1 118 ? 10.75300  8.85500   50.29700  1.000 8.63000  ? 119 ASP A N   1 
ATOM   977  C CA  . ASP A 1 118 ? 10.21300  8.91100   48.92600  1.000 11.99000 ? 119 ASP A CA  1 
ATOM   978  C C   . ASP A 1 118 ? 10.36300  10.32300  48.36300  1.000 14.39000 ? 119 ASP A C   1 
ATOM   979  O O   . ASP A 1 118 ? 9.48600   10.85000  47.64300  1.000 13.75000 ? 119 ASP A O   1 
ATOM   980  C CB  . ASP A 1 118 ? 8.75800   8.43100   48.87700  1.000 8.80000  ? 119 ASP A CB  1 
ATOM   981  C CG  . ASP A 1 118 ? 8.64100   6.92600   49.06700  1.000 11.28000 ? 119 ASP A CG  1 
ATOM   982  O OD1 . ASP A 1 118 ? 9.65000   6.19400   48.84000  1.000 13.68000 ? 119 ASP A OD1 1 
ATOM   983  O OD2 . ASP A 1 118 ? 7.57600   6.45400   49.50900  1.000 16.92000 ? 119 ASP A OD2 1 
ATOM   984  N N   . GLY A 1 119 ? 11.49400  10.94200  48.68400  1.000 13.67000 ? 120 GLY A N   1 
ATOM   985  C CA  . GLY A 1 119 ? 11.77500  12.21000  48.04900  1.000 13.46000 ? 120 GLY A CA  1 
ATOM   986  C C   . GLY A 1 119 ? 11.13500  13.42500  48.69200  1.000 17.96000 ? 120 GLY A C   1 
ATOM   987  O O   . GLY A 1 119 ? 11.37800  14.55000  48.21700  1.000 15.83000 ? 120 GLY A O   1 
ATOM   988  N N   . LYS A 1 120 ? 10.34500  13.25600  49.75000  1.000 13.71000 ? 121 LYS A N   1 
ATOM   989  C CA  . LYS A 1 120 ? 9.69500   14.38200  50.44700  1.000 13.42000 ? 121 LYS A CA  1 
ATOM   990  C C   . LYS A 1 120 ? 10.32300  14.55400  51.80400  1.000 12.96000 ? 121 LYS A C   1 
ATOM   991  O O   . LYS A 1 120 ? 10.54300  13.55500  52.49700  1.000 13.27000 ? 121 LYS A O   1 
ATOM   992  C CB  . LYS A 1 120 ? 8.18400   14.16900  50.69400  1.000 14.55000 ? 121 LYS A CB  1 
ATOM   993  C CG  . LYS A 1 120 ? 7.44600   13.92500  49.39000  1.000 23.96000 ? 121 LYS A CG  1 
ATOM   994  C CD  . LYS A 1 120 ? 6.01000   13.38000  49.60100  1.000 40.13000 ? 121 LYS A CD  1 
ATOM   995  C CE  . LYS A 1 120 ? 5.26500   14.15300  50.66400  1.000 41.78000 ? 121 LYS A CE  1 
ATOM   996  N NZ  . LYS A 1 120 ? 3.78900   13.87000  50.52300  1.000 59.26000 ? 121 LYS A NZ  1 
ATOM   997  N N   . ASP A 1 121 ? 10.54500  15.82200  52.20600  1.000 14.91000 ? 122 ASP A N   1 
ATOM   998  C CA  . ASP A 1 121 ? 10.99200  16.10200  53.58100  1.000 15.28000 ? 122 ASP A CA  1 
ATOM   999  C C   . ASP A 1 121 ? 10.16800  15.29700  54.58400  1.000 18.91000 ? 122 ASP A C   1 
ATOM   1000 O O   . ASP A 1 121 ? 8.92900   15.25200  54.50600  1.000 13.00000 ? 122 ASP A O   1 
ATOM   1001 C CB  . ASP A 1 121 ? 10.87000  17.59100  53.93100  1.000 16.88000 ? 122 ASP A CB  1 
ATOM   1002 C CG  . ASP A 1 121 ? 11.89700  18.47800  53.19200  1.000 29.06000 ? 122 ASP A CG  1 
ATOM   1003 O OD1 . ASP A 1 121 ? 12.96200  18.01100  52.79600  1.000 22.71000 ? 122 ASP A OD1 1 
ATOM   1004 O OD2 . ASP A 1 121 ? 11.67300  19.69900  53.11400  1.000 33.74000 ? 122 ASP A OD2 1 
ATOM   1005 N N   . TYR A 1 122 ? 10.86400  14.63700  55.51800  1.000 13.78000 ? 123 TYR A N   1 
ATOM   1006 C CA  . TYR A 1 122 ? 10.22100  13.80500  56.52900  1.000 15.63000 ? 123 TYR A CA  1 
ATOM   1007 C C   . TYR A 1 122 ? 10.50600  14.35100  57.93100  1.000 18.22000 ? 123 TYR A C   1 
ATOM   1008 O O   . TYR A 1 122 ? 9.56600   14.73800  58.61600  1.000 13.23000 ? 123 TYR A O   1 
ATOM   1009 C CB  . TYR A 1 122 ? 10.67300  12.31000  56.37600  1.000 13.29000 ? 123 TYR A CB  1 
ATOM   1010 C CG  . TYR A 1 122 ? 10.02600  11.34000  57.36500  1.000 8.44000  ? 123 TYR A CG  1 
ATOM   1011 C CD1 . TYR A 1 122 ? 8.81100   10.80100  57.14100  1.000 10.11000 ? 123 TYR A CD1 1 
ATOM   1012 C CD2 . TYR A 1 122 ? 10.68400  11.00400  58.53500  1.000 12.69000 ? 123 TYR A CD2 1 
ATOM   1013 C CE1 . TYR A 1 122 ? 8.22700   9.94100   58.00400  1.000 12.28000 ? 123 TYR A CE1 1 
ATOM   1014 C CE2 . TYR A 1 122 ? 10.10800  10.14600  59.47500  1.000 11.43000 ? 123 TYR A CE2 1 
ATOM   1015 C CZ  . TYR A 1 122 ? 8.86700   9.62200   59.18200  1.000 15.78000 ? 123 TYR A CZ  1 
ATOM   1016 O OH  . TYR A 1 122 ? 8.22600   8.77300   60.01200  1.000 14.32000 ? 123 TYR A OH  1 
ATOM   1017 N N   . ILE A 1 123 ? 11.77600  14.49000  58.34100  1.000 11.87000 ? 124 ILE A N   1 
ATOM   1018 C CA  . ILE A 1 123 ? 12.09900  15.02100  59.64600  1.000 13.53000 ? 124 ILE A CA  1 
ATOM   1019 C C   . ILE A 1 123 ? 13.45300  15.70000  59.55600  1.000 18.37000 ? 124 ILE A C   1 
ATOM   1020 O O   . ILE A 1 123 ? 14.36000  15.22700  58.84500  1.000 15.09000 ? 124 ILE A O   1 
ATOM   1021 C CB  . ILE A 1 123 ? 12.05200  13.92800  60.73300  1.000 11.80000 ? 124 ILE A CB  1 
ATOM   1022 C CG1 . ILE A 1 123 ? 12.13900  14.55600  62.15400  1.000 13.75000 ? 124 ILE A CG1 1 
ATOM   1023 C CG2 . ILE A 1 123 ? 13.21900  12.86700  60.56800  1.000 12.67000 ? 124 ILE A CG2 1 
ATOM   1024 C CD1 . ILE A 1 123 ? 11.88600  13.59300  63.30400  1.000 15.70000 ? 124 ILE A CD1 1 
ATOM   1025 N N   . ALA A 1 124 ? 13.59500  16.82000  60.27700  1.000 15.91000 ? 125 ALA A N   1 
ATOM   1026 C CA  . ALA A 1 124 ? 14.85500  17.54800  60.26000  1.000 16.54000 ? 125 ALA A CA  1 
ATOM   1027 C C   . ALA A 1 124 ? 15.22300  18.05800  61.64600  1.000 20.38000 ? 125 ALA A C   1 
ATOM   1028 O O   . ALA A 1 124 ? 14.35000  18.45200  62.42900  1.000 17.16000 ? 125 ALA A O   1 
ATOM   1029 C CB  . ALA A 1 124 ? 14.76400  18.73200  59.32600  1.000 18.46000 ? 125 ALA A CB  1 
ATOM   1030 N N   . LEU A 1 125 ? 16.51800  18.03000  61.93400  1.000 12.88000 ? 126 LEU A N   1 
ATOM   1031 C CA  . LEU A 1 125 ? 17.07300  18.62100  63.14400  1.000 17.63000 ? 126 LEU A CA  1 
ATOM   1032 C C   . LEU A 1 125 ? 17.00600  20.13200  63.00800  1.000 18.74000 ? 126 LEU A C   1 
ATOM   1033 O O   . LEU A 1 125 ? 17.35200  20.69100  61.94700  1.000 18.56000 ? 126 LEU A O   1 
ATOM   1034 C CB  . LEU A 1 125 ? 18.52900  18.16800  63.31100  1.000 17.76000 ? 126 LEU A CB  1 
ATOM   1035 C CG  . LEU A 1 125 ? 19.18200  18.60200  64.62400  1.000 14.03000 ? 126 LEU A CG  1 
ATOM   1036 C CD1 . LEU A 1 125 ? 18.43500  17.89100  65.82400  1.000 14.99000 ? 126 LEU A CD1 1 
ATOM   1037 C CD2 . LEU A 1 125 ? 20.66600  18.24200  64.65500  1.000 17.09000 ? 126 LEU A CD2 1 
ATOM   1038 N N   . ASN A 1 126 ? 16.51400  20.79200  64.04800  1.000 19.45000 ? 127 ASN A N   1 
ATOM   1039 C CA  . ASN A 1 126 ? 16.38500  22.24500  64.01000  1.000 21.13000 ? 127 ASN A CA  1 
ATOM   1040 C C   . ASN A 1 126 ? 17.75100  22.91200  64.12400  1.000 21.32000 ? 127 ASN A C   1 
ATOM   1041 O O   . ASN A 1 126 ? 18.73800  22.30000  64.48500  1.000 23.70000 ? 127 ASN A O   1 
ATOM   1042 C CB  . ASN A 1 126 ? 15.43100  22.71700  65.12900  1.000 24.46000 ? 127 ASN A CB  1 
ATOM   1043 C CG  . ASN A 1 126 ? 13.95900  22.38200  64.80100  1.000 26.16000 ? 127 ASN A CG  1 
ATOM   1044 O OD1 . ASN A 1 126 ? 13.60800  22.32700  63.62600  1.000 25.65000 ? 127 ASN A OD1 1 
ATOM   1045 N ND2 . ASN A 1 126 ? 13.12300  22.12800  65.81100  1.000 29.06000 ? 127 ASN A ND2 1 
ATOM   1046 N N   . GLU A 1 127 ? 17.78800  24.19900  63.79400  1.000 26.04000 ? 128 GLU A N   1 
ATOM   1047 C CA  . GLU A 1 127 ? 19.02500  24.97500  63.83600  1.000 29.07000 ? 128 GLU A CA  1 
ATOM   1048 C C   . GLU A 1 127 ? 19.66800  24.96500  65.20100  1.000 26.02000 ? 128 GLU A C   1 
ATOM   1049 O O   . GLU A 1 127 ? 20.89600  25.02100  65.29500  1.000 26.54000 ? 128 GLU A O   1 
ATOM   1050 C CB  . GLU A 1 127 ? 18.74600  26.42000  63.42300  1.000 38.56000 ? 128 GLU A CB  1 
ATOM   1051 C CG  . GLU A 1 127 ? 18.73000  26.66200  61.92500  1.000 52.60000 ? 128 GLU A CG  1 
ATOM   1052 C CD  . GLU A 1 127 ? 20.14000  26.56000  61.33000  1.000 70.57000 ? 128 GLU A CD  1 
ATOM   1053 O OE1 . GLU A 1 127 ? 21.03300  27.28600  61.85900  1.000 66.67000 ? 128 GLU A OE1 1 
ATOM   1054 O OE2 . GLU A 1 127 ? 20.36500  25.75800  60.37200  1.000 63.26000 ? 128 GLU A OE2 1 
ATOM   1055 N N   . ASP A 1 128 ? 18.87200  24.89900  66.27100  1.000 24.10000 ? 129 ASP A N   1 
ATOM   1056 C CA  . ASP A 1 128 ? 19.46400  24.91300  67.60600  1.000 30.48000 ? 129 ASP A CA  1 
ATOM   1057 C C   . ASP A 1 128 ? 20.07700  23.57900  67.98100  1.000 26.15000 ? 129 ASP A C   1 
ATOM   1058 O O   . ASP A 1 128 ? 20.68400  23.48300  69.04600  1.000 26.01000 ? 129 ASP A O   1 
ATOM   1059 C CB  . ASP A 1 128 ? 18.42900  25.35100  68.67900  1.000 27.44000 ? 129 ASP A CB  1 
ATOM   1060 C CG  . ASP A 1 128 ? 17.22900  24.39000  68.81200  1.000 39.22000 ? 129 ASP A CG  1 
ATOM   1061 O OD1 . ASP A 1 128 ? 17.22900  23.28100  68.24500  1.000 35.83000 ? 129 ASP A OD1 1 
ATOM   1062 O OD2 . ASP A 1 128 ? 16.23200  24.74700  69.49300  1.000 44.70000 ? 129 ASP A OD2 1 
ATOM   1063 N N   . LEU A 1 129 ? 19.91600  22.54600  67.14400  1.000 19.24000 ? 130 LEU A N   1 
ATOM   1064 C CA  . LEU A 1 129 ? 20.45400  21.21200  67.40400  1.000 20.23000 ? 130 LEU A CA  1 
ATOM   1065 C C   . LEU A 1 129 ? 19.88600  20.59100  68.67500  1.000 23.69000 ? 130 LEU A C   1 
ATOM   1066 O O   . LEU A 1 129 ? 20.46700  19.64400  69.20700  1.000 23.51000 ? 130 LEU A O   1 
ATOM   1067 C CB  . LEU A 1 129 ? 21.99600  21.20800  67.46200  1.000 21.74000 ? 130 LEU A CB  1 
ATOM   1068 C CG  . LEU A 1 129 ? 22.75600  21.96700  66.36600  1.000 25.22000 ? 130 LEU A CG  1 
ATOM   1069 C CD1 . LEU A 1 129 ? 24.29200  21.92100  66.51000  1.000 19.52000 ? 130 LEU A CD1 1 
ATOM   1070 C CD2 . LEU A 1 129 ? 22.30000  21.47800  64.97500  1.000 22.26000 ? 130 LEU A CD2 1 
ATOM   1071 N N   . ARG A 1 130 ? 18.70200  21.03100  69.11300  1.000 20.42000 ? 131 ARG A N   1 
ATOM   1072 C CA  . ARG A 1 130 ? 18.08300  20.52400  70.32900  1.000 28.17000 ? 131 ARG A CA  1 
ATOM   1073 C C   . ARG A 1 130 ? 16.70700  19.94100  70.11500  1.000 27.58000 ? 131 ARG A C   1 
ATOM   1074 O O   . ARG A 1 130 ? 16.13300  19.36600  71.06400  1.000 24.83000 ? 131 ARG A O   1 
ATOM   1075 C CB  . ARG A 1 130 ? 17.94400  21.63400  71.39600  1.000 34.19000 ? 131 ARG A CB  1 
ATOM   1076 C CG  . ARG A 1 130 ? 19.24600  22.11600  71.99400  1.000 39.91000 ? 131 ARG A CG  1 
ATOM   1077 C CD  . ARG A 1 130 ? 19.10300  23.56200  72.48500  1.000 41.36000 ? 131 ARG A CD  1 
ATOM   1078 N NE  . ARG A 1 130 ? 20.35200  24.07200  73.03400  1.000 49.25000 ? 131 ARG A NE  1 
ATOM   1079 C CZ  . ARG A 1 130 ? 20.91100  23.66400  74.17100  1.000 59.96000 ? 131 ARG A CZ  1 
ATOM   1080 N NH1 . ARG A 1 130 ? 20.37700  22.69600  74.91800  1.000 47.77000 ? 131 ARG A NH1 1 
ATOM   1081 N NH2 . ARG A 1 130 ? 22.03700  24.23800  74.57200  1.000 63.89000 ? 131 ARG A NH2 1 
ATOM   1082 N N   . SER A 1 131 ? 16.15200  20.08100  68.91700  1.000 20.17000 ? 132 SER A N   1 
ATOM   1083 C CA  . SER A 1 131 ? 14.77800  19.66300  68.68900  1.000 27.35000 ? 132 SER A CA  1 
ATOM   1084 C C   . SER A 1 131 ? 14.59000  19.36800  67.20400  1.000 19.28000 ? 132 SER A C   1 
ATOM   1085 O O   . SER A 1 131 ? 15.45800  19.65200  66.36400  1.000 19.47000 ? 132 SER A O   1 
ATOM   1086 C CB  . SER A 1 131 ? 13.76700  20.73700  69.10300  1.000 30.44000 ? 132 SER A CB  1 
ATOM   1087 O OG  . SER A 1 131 ? 14.17000  21.97300  68.52600  1.000 29.21000 ? 132 SER A OG  1 
ATOM   1088 N N   . TRP A 1 132 ? 13.44400  18.80000  66.89700  1.000 19.29000 ? 133 TRP A N   1 
ATOM   1089 C CA  . TRP A 1 132 ? 13.14000  18.33300  65.55000  1.000 18.27000 ? 133 TRP A CA  1 
ATOM   1090 C C   . TRP A 1 132 ? 11.94500  19.06200  64.95000  1.000 22.17000 ? 133 TRP A C   1 
ATOM   1091 O O   . TRP A 1 132 ? 11.07100  19.53500  65.67500  1.000 23.64000 ? 133 TRP A O   1 
ATOM   1092 C CB  . TRP A 1 132 ? 12.83000  16.84500  65.60700  1.000 19.42000 ? 133 TRP A CB  1 
ATOM   1093 C CG  . TRP A 1 132 ? 13.84300  16.07900  66.33900  1.000 20.59000 ? 133 TRP A CG  1 
ATOM   1094 C CD1 . TRP A 1 132 ? 13.91000  15.77300  67.69800  1.000 19.91000 ? 133 TRP A CD1 1 
ATOM   1095 C CD2 . TRP A 1 132 ? 14.99400  15.54300  65.74100  1.000 18.32000 ? 133 TRP A CD2 1 
ATOM   1096 N NE1 . TRP A 1 132 ? 15.05900  15.01100  67.94400  1.000 21.00000 ? 133 TRP A NE1 1 
ATOM   1097 C CE2 . TRP A 1 132 ? 15.75000  14.89300  66.76400  1.000 19.89000 ? 133 TRP A CE2 1 
ATOM   1098 C CE3 . TRP A 1 132 ? 15.47500  15.54300  64.42600  1.000 15.21000 ? 133 TRP A CE3 1 
ATOM   1099 C CZ2 . TRP A 1 132 ? 16.95800  14.22700  66.50000  1.000 20.82000 ? 133 TRP A CZ2 1 
ATOM   1100 C CZ3 . TRP A 1 132 ? 16.69900  14.85600  64.17700  1.000 15.43000 ? 133 TRP A CZ3 1 
ATOM   1101 C CH2 . TRP A 1 132 ? 17.40400  14.23500  65.19400  1.000 20.13000 ? 133 TRP A CH2 1 
ATOM   1102 N N   . THR A 1 133 ? 11.86300  19.08700  63.61100  1.000 16.99000 ? 134 THR A N   1 
ATOM   1103 C CA  . THR A 1 133 ? 10.63200  19.42700  62.88700  1.000 22.16000 ? 134 THR A CA  1 
ATOM   1104 C C   . THR A 1 133 ? 10.22400  18.22400  62.04800  1.000 21.51000 ? 134 THR A C   1 
ATOM   1105 O O   . THR A 1 133 ? 11.00200  17.76600  61.16700  1.000 17.87000 ? 134 THR A O   1 
ATOM   1106 C CB  . THR A 1 133 ? 10.82100  20.67500  62.00400  1.000 23.52000 ? 134 THR A CB  1 
ATOM   1107 O OG1 . THR A 1 133 ? 11.14900  21.80500  62.83500  1.000 24.19000 ? 134 THR A OG1 1 
ATOM   1108 C CG2 . THR A 1 133 ? 9.59100   20.99200  61.23400  1.000 23.26000 ? 134 THR A CG2 1 
ATOM   1109 N N   . ALA A 1 134 ? 9.00300   17.72800  62.31300  1.000 18.66000 ? 135 ALA A N   1 
ATOM   1110 C CA  . ALA A 1 134 ? 8.37600   16.62300  61.58300  1.000 20.30000 ? 135 ALA A CA  1 
ATOM   1111 C C   . ALA A 1 134 ? 7.45300   17.14300  60.48400  1.000 21.96000 ? 135 ALA A C   1 
ATOM   1112 O O   . ALA A 1 134 ? 6.63000   18.04400  60.70500  1.000 20.30000 ? 135 ALA A O   1 
ATOM   1113 C CB  . ALA A 1 134 ? 7.55800   15.73800  62.53200  1.000 17.02000 ? 135 ALA A CB  1 
ATOM   1114 N N   . ALA A 1 135 ? 7.52500   16.52500  59.32200  1.000 16.51000 ? 136 ALA A N   1 
ATOM   1115 C CA  . ALA A 1 135 ? 6.70700   17.04600  58.21400  1.000 17.93000 ? 136 ALA A CA  1 
ATOM   1116 C C   . ALA A 1 135 ? 5.26600   16.57100  58.24400  1.000 19.30000 ? 136 ALA A C   1 
ATOM   1117 O O   . ALA A 1 135 ? 4.42100   17.19600  57.59400  1.000 22.03000 ? 136 ALA A O   1 
ATOM   1118 C CB  . ALA A 1 135 ? 7.28300   16.66100  56.86900  1.000 20.41000 ? 136 ALA A CB  1 
ATOM   1119 N N   . ASP A 1 136 ? 4.95800   15.46300  58.91300  1.000 19.77000 ? 137 ASP A N   1 
ATOM   1120 C CA  . ASP A 1 136 ? 3.59300   14.93900  58.86800  1.000 21.57000 ? 137 ASP A CA  1 
ATOM   1121 C C   . ASP A 1 136 ? 3.40000   14.06100  60.09300  1.000 19.08000 ? 137 ASP A C   1 
ATOM   1122 O O   . ASP A 1 136 ? 4.28400   13.96200  60.93900  1.000 17.09000 ? 137 ASP A O   1 
ATOM   1123 C CB  . ASP A 1 136 ? 3.29800   14.19100  57.55100  1.000 24.94000 ? 137 ASP A CB  1 
ATOM   1124 C CG  . ASP A 1 136 ? 4.18100   12.95200  57.34700  1.000 20.92000 ? 137 ASP A CG  1 
ATOM   1125 O OD1 . ASP A 1 136 ? 4.81900   12.47800  58.31500  1.000 15.96000 ? 137 ASP A OD1 1 
ATOM   1126 O OD2 . ASP A 1 136 ? 4.19100   12.39900  56.23500  1.000 24.21000 ? 137 ASP A OD2 1 
ATOM   1127 N N   . THR A 1 137 ? 2.26200   13.37900  60.17500  1.000 19.66000 ? 138 THR A N   1 
ATOM   1128 C CA  . THR A 1 137 ? 1.94800   12.71400  61.41400  1.000 16.44000 ? 138 THR A CA  1 
ATOM   1129 C C   . THR A 1 137 ? 2.76400   11.42900  61.58000  1.000 19.63000 ? 138 THR A C   1 
ATOM   1130 O O   . THR A 1 137 ? 2.98900   11.00300  62.71500  1.000 18.81000 ? 138 THR A O   1 
ATOM   1131 C CB  . THR A 1 137 ? 0.44000   12.45600  61.51800  1.000 27.22000 ? 138 THR A CB  1 
ATOM   1132 O OG1 . THR A 1 137 ? 0.03400   11.69800  60.39300  1.000 29.57000 ? 138 THR A OG1 1 
ATOM   1133 C CG2 . THR A 1 137 ? -0.33600  13.74300  61.53700  1.000 22.55000 ? 138 THR A CG2 1 
ATOM   1134 N N   . ALA A 1 138 ? 3.22800   10.81900  60.48300  1.000 17.86000 ? 139 ALA A N   1 
ATOM   1135 C CA  . ALA A 1 138 ? 4.16200   9.69800   60.61400  1.000 17.85000 ? 139 ALA A CA  1 
ATOM   1136 C C   . ALA A 1 138 ? 5.47100   10.17100  61.22500  1.000 15.63000 ? 139 ALA A C   1 
ATOM   1137 O O   . ALA A 1 138 ? 6.02100   9.54600   62.14400  1.000 15.68000 ? 139 ALA A O   1 
ATOM   1138 C CB  . ALA A 1 138 ? 4.42000   9.05400   59.23800  1.000 10.50000 ? 139 ALA A CB  1 
ATOM   1139 N N   . ALA A 1 139 ? 6.01000   11.26100  60.71400  1.000 14.51000 ? 140 ALA A N   1 
ATOM   1140 C CA  . ALA A 1 139 ? 7.28300   11.74200  61.26000  1.000 15.94000 ? 140 ALA A CA  1 
ATOM   1141 C C   . ALA A 1 139 ? 7.15800   12.17600  62.71900  1.000 16.46000 ? 140 ALA A C   1 
ATOM   1142 O O   . ALA A 1 139 ? 8.15600   12.19200  63.45600  1.000 16.71000 ? 140 ALA A O   1 
ATOM   1143 C CB  . ALA A 1 139 ? 7.79600   12.90400  60.40900  1.000 15.51000 ? 140 ALA A CB  1 
ATOM   1144 N N   . GLN A 1 140 ? 5.96100   12.56800  63.15500  1.000 16.04000 ? 141 GLN A N   1 
ATOM   1145 C CA  . GLN A 1 140 ? 5.79600   12.87600  64.59000  1.000 14.69000 ? 141 GLN A CA  1 
ATOM   1146 C C   . GLN A 1 140 ? 5.97800   11.62600  65.44200  1.000 18.26000 ? 141 GLN A C   1 
ATOM   1147 O O   . GLN A 1 140 ? 6.43800   11.71900  66.57800  1.000 17.17000 ? 141 GLN A O   1 
ATOM   1148 C CB  . GLN A 1 140 ? 4.42000   13.52400  64.82500  1.000 16.67000 ? 141 GLN A CB  1 
ATOM   1149 C CG  . GLN A 1 140 ? 4.16200   14.87200  64.07300  1.000 20.50000 ? 141 GLN A CG  1 
ATOM   1150 C CD  . GLN A 1 140 ? 2.61500   15.30200  64.06500  1.000 24.24000 ? 141 GLN A CD  1 
ATOM   1151 O OE1 . GLN A 1 140 ? 1.81000   14.75100  64.77500  1.000 30.26000 ? 141 GLN A OE1 1 
ATOM   1152 N NE2 . GLN A 1 140 ? 2.25400   16.24500  63.21100  1.000 29.00000 ? 141 GLN A NE2 1 
ATOM   1153 N N   . ILE A 1 141 ? 5.66400   10.43900  64.89800  1.000 16.96000 ? 142 ILE A N   1 
ATOM   1154 C CA  . ILE A 1 141 ? 5.96000   9.20100   65.61800  1.000 16.05000 ? 142 ILE A CA  1 
ATOM   1155 C C   . ILE A 1 141 ? 7.46800   9.03500   65.74400  1.000 15.01000 ? 142 ILE A C   1 
ATOM   1156 O O   . ILE A 1 141 ? 8.00600   8.70600   66.83100  1.000 16.19000 ? 142 ILE A O   1 
ATOM   1157 C CB  . ILE A 1 141 ? 5.31200   7.98300   64.90700  1.000 16.78000 ? 142 ILE A CB  1 
ATOM   1158 C CG1 . ILE A 1 141 ? 3.75600   8.16500   64.81700  1.000 16.18000 ? 142 ILE A CG1 1 
ATOM   1159 C CG2 . ILE A 1 141 ? 5.73300   6.68000   65.56700  1.000 15.34000 ? 142 ILE A CG2 1 
ATOM   1160 C CD1 . ILE A 1 141 ? 3.01100   7.13400   63.86900  1.000 23.62000 ? 142 ILE A CD1 1 
ATOM   1161 N N   . THR A 1 142 ? 8.18500   9.26600   64.62500  1.000 14.40000 ? 143 THR A N   1 
ATOM   1162 C CA  . THR A 1 142 ? 9.64500   9.19900   64.66200  1.000 16.30000 ? 143 THR A CA  1 
ATOM   1163 C C   . THR A 1 142 ? 10.19700  10.21500  65.65100  1.000 14.99000 ? 143 THR A C   1 
ATOM   1164 O O   . THR A 1 142 ? 11.06800  9.90300   66.46500  1.000 14.78000 ? 143 THR A O   1 
ATOM   1165 C CB  . THR A 1 142 ? 10.18700  9.44400   63.25000  1.000 14.49000 ? 143 THR A CB  1 
ATOM   1166 O OG1 . THR A 1 142 ? 9.66900   8.41300   62.40900  1.000 14.53000 ? 143 THR A OG1 1 
ATOM   1167 C CG2 . THR A 1 142 ? 11.74400  9.41700   63.20200  1.000 13.01000 ? 143 THR A CG2 1 
ATOM   1168 N N   . GLN A 1 143 ? 9.68600   11.44400  65.60000  1.000 13.83000 ? 144 GLN A N   1 
ATOM   1169 C CA  . GLN A 1 143 ? 10.20100  12.47300  66.51100  1.000 14.64000 ? 144 GLN A CA  1 
ATOM   1170 C C   . GLN A 1 143 ? 10.04700  12.05500  67.98100  1.000 14.54000 ? 144 GLN A C   1 
ATOM   1171 O O   . GLN A 1 143 ? 10.94600  12.27600  68.79900  1.000 16.07000 ? 144 GLN A O   1 
ATOM   1172 C CB  . GLN A 1 143 ? 9.45400   13.78700  66.24100  1.000 17.07000 ? 144 GLN A CB  1 
ATOM   1173 C CG  . GLN A 1 143 ? 9.80200   14.90200  67.21800  1.000 18.24000 ? 144 GLN A CG  1 
ATOM   1174 C CD  . GLN A 1 143 ? 9.14000   16.25100  66.88300  1.000 26.00000 ? 144 GLN A CD  1 
ATOM   1175 O OE1 . GLN A 1 143 ? 8.60500   16.46300  65.79200  1.000 30.67000 ? 144 GLN A OE1 1 
ATOM   1176 N NE2 . GLN A 1 143 ? 9.08700   17.12000  67.86600  1.000 32.20000 ? 144 GLN A NE2 1 
ATOM   1177 N N   . ARG A 1 144 ? 8.90600   11.45700  68.33300  1.000 16.57000 ? 145 ARG A N   1 
ATOM   1178 C CA  . ARG A 1 144 ? 8.69100   11.07400  69.73500  1.000 18.03000 ? 145 ARG A CA  1 
ATOM   1179 C C   . ARG A 1 144 ? 9.62100   9.95700   70.14500  1.000 19.98000 ? 145 ARG A C   1 
ATOM   1180 O O   . ARG A 1 144 ? 10.09300  9.93800   71.27900  1.000 18.20000 ? 145 ARG A O   1 
ATOM   1181 C CB  . ARG A 1 144 ? 7.23400   10.64500  69.99700  1.000 20.90000 ? 145 ARG A CB  1 
ATOM   1182 C CG  . ARG A 1 144 ? 6.24400   11.80600  70.01400  1.000 22.09000 ? 145 ARG A CG  1 
ATOM   1183 C CD  . ARG A 1 144 ? 4.80800   11.39700  70.45100  1.000 23.88000 ? 145 ARG A CD  1 
ATOM   1184 N NE  . ARG A 1 144 ? 4.16600   10.66800  69.37000  1.000 31.13000 ? 145 ARG A NE  1 
ATOM   1185 C CZ  . ARG A 1 144 ? 3.38000   11.22000  68.44800  1.000 29.78000 ? 145 ARG A CZ  1 
ATOM   1186 N NH1 . ARG A 1 144 ? 3.20200   12.53300  68.38100  1.000 34.26000 ? 145 ARG A NH1 1 
ATOM   1187 N NH2 . ARG A 1 144 ? 2.81600   10.44500  67.52900  1.000 23.80000 ? 145 ARG A NH2 1 
ATOM   1188 N N   . LYS A 1 145 ? 9.94200   9.03800   69.22100  1.000 16.27000 ? 146 LYS A N   1 
ATOM   1189 C CA  . LYS A 1 145 ? 10.95200  8.01500   69.50800  1.000 16.85000 ? 146 LYS A CA  1 
ATOM   1190 C C   . LYS A 1 145 ? 12.33200  8.65200   69.76200  1.000 15.21000 ? 146 LYS A C   1 
ATOM   1191 O O   . LYS A 1 145 ? 13.03900  8.31800   70.71900  1.000 18.45000 ? 146 LYS A O   1 
ATOM   1192 C CB  . LYS A 1 145 ? 11.05500  7.07100   68.29500  1.000 19.83000 ? 146 LYS A CB  1 
ATOM   1193 C CG  . LYS A 1 145 ? 9.92900   6.13200   68.04000  1.000 18.96000 ? 146 LYS A CG  1 
ATOM   1194 C CD  . LYS A 1 145 ? 10.38900  5.05600   66.97100  1.000 17.07000 ? 146 LYS A CD  1 
ATOM   1195 C CE  . LYS A 1 145 ? 9.24400   4.18100   66.45600  1.000 20.78000 ? 146 LYS A CE  1 
ATOM   1196 N NZ  . LYS A 1 145 ? 9.83400   3.16800   65.50900  1.000 17.51000 ? 146 LYS A NZ  1 
ATOM   1197 N N   . TRP A 1 146 ? 12.73700  9.56700   68.90100  1.000 15.43000 ? 147 TRP A N   1 
ATOM   1198 C CA  . TRP A 1 146 ? 14.06600  10.17000  69.03800  1.000 18.23000 ? 147 TRP A CA  1 
ATOM   1199 C C   . TRP A 1 146 ? 14.11000  11.07500  70.26700  1.000 18.90000 ? 147 TRP A C   1 
ATOM   1200 O O   . TRP A 1 146 ? 15.14700  11.20900  70.92800  1.000 19.57000 ? 147 TRP A O   1 
ATOM   1201 C CB  . TRP A 1 146 ? 14.37800  10.96100  67.73900  1.000 14.32000 ? 147 TRP A CB  1 
ATOM   1202 C CG  . TRP A 1 146 ? 14.53900  10.03000  66.57100  1.000 14.67000 ? 147 TRP A CG  1 
ATOM   1203 C CD1 . TRP A 1 146 ? 14.47500  8.65300   66.58700  1.000 15.01000 ? 147 TRP A CD1 1 
ATOM   1204 C CD2 . TRP A 1 146 ? 14.83100  10.40200  65.21300  1.000 16.90000 ? 147 TRP A CD2 1 
ATOM   1205 N NE1 . TRP A 1 146 ? 14.72700  8.15900   65.29200  1.000 15.09000 ? 147 TRP A NE1 1 
ATOM   1206 C CE2 . TRP A 1 146 ? 14.89900  9.21300   64.44600  1.000 14.04000 ? 147 TRP A CE2 1 
ATOM   1207 C CE3 . TRP A 1 146 ? 15.01500  11.64200  64.56000  1.000 17.42000 ? 147 TRP A CE3 1 
ATOM   1208 C CZ2 . TRP A 1 146 ? 15.15900  9.22800   63.06000  1.000 12.20000 ? 147 TRP A CZ2 1 
ATOM   1209 C CZ3 . TRP A 1 146 ? 15.25200  11.64500  63.17700  1.000 14.67000 ? 147 TRP A CZ3 1 
ATOM   1210 C CH2 . TRP A 1 146 ? 15.36100  10.45800  62.46800  1.000 13.19000 ? 147 TRP A CH2 1 
ATOM   1211 N N   . GLU A 1 147 ? 12.99100  11.71900  70.57300  1.000 19.99000 ? 148 GLU A N   1 
ATOM   1212 C CA  . GLU A 1 147 ? 12.94200  12.51700  71.80000  1.000 16.84000 ? 148 GLU A CA  1 
ATOM   1213 C C   . GLU A 1 147 ? 13.09800  11.63600  73.02200  1.000 22.59000 ? 148 GLU A C   1 
ATOM   1214 O O   . GLU A 1 147 ? 13.82700  11.98700  73.95200  1.000 20.54000 ? 148 GLU A O   1 
ATOM   1215 C CB  . GLU A 1 147 ? 11.64700  13.28500  71.87800  1.000 18.95000 ? 148 GLU A CB  1 
ATOM   1216 C CG  . GLU A 1 147 ? 11.65900  14.51300  70.95400  1.000 17.13000 ? 148 GLU A CG  1 
ATOM   1217 C CD  . GLU A 1 147 ? 10.31600  15.15500  70.79800  1.000 27.86000 ? 148 GLU A CD  1 
ATOM   1218 O OE1 . GLU A 1 147 ? 9.29100   14.54500  71.19400  1.000 23.46000 ? 148 GLU A OE1 1 
ATOM   1219 O OE2 . GLU A 1 147 ? 10.28500  16.29000  70.27400  1.000 27.42000 ? 148 GLU A OE2 1 
ATOM   1220 N N   . ALA A 1 148 ? 12.43100  10.47800  73.03300  1.000 19.50000 ? 149 ALA A N   1 
ATOM   1221 C CA  . ALA A 1 148 ? 12.58600  9.56200   74.16000  1.000 20.14000 ? 149 ALA A CA  1 
ATOM   1222 C C   . ALA A 1 148 ? 14.00400  9.03600   74.26600  1.000 25.20000 ? 149 ALA A C   1 
ATOM   1223 O O   . ALA A 1 148 ? 14.49200  8.77400   75.37600  1.000 20.93000 ? 149 ALA A O   1 
ATOM   1224 C CB  . ALA A 1 148 ? 11.58000  8.41100   74.02800  1.000 20.29000 ? 149 ALA A CB  1 
ATOM   1225 N N   . ALA A 1 149 ? 14.69500  8.88500   73.14100  1.000 20.83000 ? 150 ALA A N   1 
ATOM   1226 C CA  . ALA A 1 149 ? 16.08900  8.46400   73.15400  1.000 22.31000 ? 150 ALA A CA  1 
ATOM   1227 C C   . ALA A 1 149 ? 17.05400  9.58600   73.47300  1.000 22.46000 ? 150 ALA A C   1 
ATOM   1228 O O   . ALA A 1 149 ? 18.25500  9.31700   73.58800  1.000 19.34000 ? 150 ALA A O   1 
ATOM   1229 C CB  . ALA A 1 149 ? 16.50200  7.85400   71.77300  1.000 22.60000 ? 150 ALA A CB  1 
ATOM   1230 N N   . ARG A 1 150 ? 16.56800  10.82500  73.56700  1.000 20.19000 ? 151 ARG A N   1 
ATOM   1231 C CA  . ARG A 1 150 ? 17.39800  12.00900  73.74200  1.000 20.01000 ? 151 ARG A CA  1 
ATOM   1232 C C   . ARG A 1 150 ? 18.49100  12.10100  72.66700  1.000 17.49000 ? 151 ARG A C   1 
ATOM   1233 O O   . ARG A 1 150 ? 19.61700  12.48600  72.92100  1.000 19.64000 ? 151 ARG A O   1 
ATOM   1234 C CB  . ARG A 1 150 ? 17.97400  12.06900  75.17200  1.000 22.45000 ? 151 ARG A CB  1 
ATOM   1235 C CG  . ARG A 1 150 ? 16.84200  12.03600  76.20300  1.000 21.60000 ? 151 ARG A CG  1 
ATOM   1236 C CD  . ARG A 1 150 ? 17.36900  11.65800  77.56100  1.000 42.77000 ? 151 ARG A CD  1 
ATOM   1237 N NE  . ARG A 1 150 ? 16.33900  11.69700  78.59700  1.000 50.62000 ? 151 ARG A NE  1 
ATOM   1238 C CZ  . ARG A 1 150 ? 16.54400  11.34600  79.86600  1.000 46.31000 ? 151 ARG A CZ  1 
ATOM   1239 N NH1 . ARG A 1 150 ? 17.72800  10.90200  80.28600  1.000 42.03000 ? 151 ARG A NH1 1 
ATOM   1240 N NH2 . ARG A 1 150 ? 15.53100  11.40900  80.72800  1.000 44.31000 ? 151 ARG A NH2 1 
ATOM   1241 N N   . GLU A 1 151 ? 18.12700  11.79000  71.42700  1.000 18.58000 ? 152 GLU A N   1 
ATOM   1242 C CA  . GLU A 1 151 ? 19.13800  11.69000  70.39100  1.000 18.20000 ? 152 GLU A CA  1 
ATOM   1243 C C   . GLU A 1 151 ? 19.62600  13.05000  69.94500  1.000 17.62000 ? 152 GLU A C   1 
ATOM   1244 O O   . GLU A 1 151 ? 20.73200  13.14400  69.38400  1.000 19.01000 ? 152 GLU A O   1 
ATOM   1245 C CB  . GLU A 1 151 ? 18.59400  10.88500  69.17700  1.000 18.53000 ? 152 GLU A CB  1 
ATOM   1246 C CG  . GLU A 1 151 ? 19.70800  10.33700  68.19100  1.000 16.77000 ? 152 GLU A CG  1 
ATOM   1247 C CD  . GLU A 1 151 ? 20.71700  9.36200   68.80500  1.000 17.16000 ? 152 GLU A CD  1 
ATOM   1248 O OE1 . GLU A 1 151 ? 20.40700  8.64100   69.76200  1.000 21.78000 ? 152 GLU A OE1 1 
ATOM   1249 O OE2 . GLU A 1 151 ? 21.86400  9.28500   68.30400  1.000 19.07000 ? 152 GLU A OE2 1 
ATOM   1250 N N   . ALA A 1 152 ? 18.84100  14.10500  70.15000  1.000 14.81000 ? 153 ALA A N   1 
ATOM   1251 C CA  . ALA A 1 152 ? 19.32100  15.41800  69.72100  1.000 19.93000 ? 153 ALA A CA  1 
ATOM   1252 C C   . ALA A 1 152 ? 20.61500  15.77700  70.43300  1.000 19.87000 ? 153 ALA A C   1 
ATOM   1253 O O   . ALA A 1 152 ? 21.51900  16.37400  69.83900  1.000 18.50000 ? 153 ALA A O   1 
ATOM   1254 C CB  . ALA A 1 152 ? 18.27500  16.50200  69.97200  1.000 20.93000 ? 153 ALA A CB  1 
ATOM   1255 N N   . GLU A 1 153 ? 20.73200  15.40600  71.70900  1.000 23.06000 ? 154 GLU A N   1 
ATOM   1256 C CA  . GLU A 1 153 ? 21.98900  15.64000  72.41200  1.000 18.40000 ? 154 GLU A CA  1 
ATOM   1257 C C   . GLU A 1 153 ? 23.15700  14.97200  71.69600  1.000 20.54000 ? 154 GLU A C   1 
ATOM   1258 O O   . GLU A 1 153 ? 24.27500  15.53100  71.63700  1.000 19.15000 ? 154 GLU A O   1 
ATOM   1259 C CB  . GLU A 1 153 ? 21.89400  15.07200  73.82100  1.000 23.63000 ? 154 GLU A CB  1 
ATOM   1260 C CG  . GLU A 1 153 ? 20.92200  15.79700  74.72000  1.000 33.48000 ? 154 GLU A CG  1 
ATOM   1261 C CD  . GLU A 1 153 ? 21.42200  17.18000  75.16900  1.000 37.69000 ? 154 GLU A CD  1 
ATOM   1262 O OE1 . GLU A 1 153 ? 22.63100  17.54500  74.93900  1.000 38.88000 ? 154 GLU A OE1 1 
ATOM   1263 O OE2 . GLU A 1 153 ? 20.60500  17.87700  75.80900  1.000 33.06000 ? 154 GLU A OE2 1 
ATOM   1264 N N   . GLN A 1 154 ? 22.93500  13.73900  71.19500  1.000 16.86000 ? 155 GLN A N   1 
ATOM   1265 C CA  . GLN A 1 154 ? 24.01300  13.04200  70.47500  1.000 19.74000 ? 155 GLN A CA  1 
ATOM   1266 C C   . GLN A 1 154 ? 24.32400  13.74200  69.14800  1.000 16.12000 ? 155 GLN A C   1 
ATOM   1267 O O   . GLN A 1 154 ? 25.48900  13.78000  68.76000  1.000 17.70000 ? 155 GLN A O   1 
ATOM   1268 C CB  . GLN A 1 154 ? 23.65300  11.57000  70.24400  1.000 21.47000 ? 155 GLN A CB  1 
ATOM   1269 C CG  . GLN A 1 154 ? 23.41100  10.77900  71.49100  1.000 24.46000 ? 155 GLN A CG  1 
ATOM   1270 C CD  . GLN A 1 154 ? 24.62100  10.85000  72.44300  1.000 34.81000 ? 155 GLN A CD  1 
ATOM   1271 O OE1 . GLN A 1 154 ? 25.73800  10.51700  72.06100  1.000 32.53000 ? 155 GLN A OE1 1 
ATOM   1272 N NE2 . GLN A 1 154 ? 24.40000  11.32600  73.65400  1.000 35.32000 ? 155 GLN A NE2 1 
ATOM   1273 N N   . TRP A 1 155 ? 23.31400  14.37200  68.49600  1.000 14.13000 ? 156 TRP A N   1 
ATOM   1274 C CA  . TRP A 1 155 ? 23.58300  15.16900  67.29400  1.000 16.14000 ? 156 TRP A CA  1 
ATOM   1275 C C   . TRP A 1 155 ? 24.36300  16.43600  67.61400  1.000 18.56000 ? 156 TRP A C   1 
ATOM   1276 O O   . TRP A 1 155 ? 25.29300  16.81700  66.88800  1.000 14.61000 ? 156 TRP A O   1 
ATOM   1277 C CB  . TRP A 1 155 ? 22.26000  15.52900  66.63700  1.000 12.63000 ? 156 TRP A CB  1 
ATOM   1278 C CG  . TRP A 1 155 ? 21.77800  14.40600  65.75100  1.000 16.83000 ? 156 TRP A CG  1 
ATOM   1279 C CD1 . TRP A 1 155 ? 20.73100  13.56400  65.97800  1.000 17.88000 ? 156 TRP A CD1 1 
ATOM   1280 C CD2 . TRP A 1 155 ? 22.35300  14.01900  64.49400  1.000 15.90000 ? 156 TRP A CD2 1 
ATOM   1281 N NE1 . TRP A 1 155 ? 20.58500  12.67300  64.86900  1.000 16.25000 ? 156 TRP A NE1 1 
ATOM   1282 C CE2 . TRP A 1 155 ? 21.60800  12.91700  63.99600  1.000 14.25000 ? 156 TRP A CE2 1 
ATOM   1283 C CE3 . TRP A 1 155 ? 23.44500  14.49800  63.74400  1.000 15.81000 ? 156 TRP A CE3 1 
ATOM   1284 C CZ2 . TRP A 1 155 ? 21.90500  12.29600  62.76800  1.000 14.15000 ? 156 TRP A CZ2 1 
ATOM   1285 C CZ3 . TRP A 1 155 ? 23.75100  13.86800  62.51600  1.000 17.48000 ? 156 TRP A CZ3 1 
ATOM   1286 C CH2 . TRP A 1 155 ? 22.95600  12.78200  62.04800  1.000 16.08000 ? 156 TRP A CH2 1 
ATOM   1287 N N   . ARG A 1 156 ? 23.95400  17.14300  68.67500  1.000 21.89000 ? 157 ARG A N   1 
ATOM   1288 C CA  . ARG A 1 156 ? 24.70200  18.32200  69.10500  1.000 17.97000 ? 157 ARG A CA  1 
ATOM   1289 C C   . ARG A 1 156 ? 26.15900  17.98500  69.35700  1.000 17.42000 ? 157 ARG A C   1 
ATOM   1290 O O   . ARG A 1 156 ? 27.05400  18.69000  68.87800  1.000 18.41000 ? 157 ARG A O   1 
ATOM   1291 C CB  . ARG A 1 156 ? 24.05200  18.91400  70.37700  1.000 20.84000 ? 157 ARG A CB  1 
ATOM   1292 C CG  . ARG A 1 156 ? 24.47500  20.40100  70.68100  1.000 28.74000 ? 157 ARG A CG  1 
ATOM   1293 C CD  . ARG A 1 156 ? 23.37500  21.19100  71.48000  1.000 39.89000 ? 157 ARG A CD  1 
ATOM   1294 N NE  . ARG A 1 156 ? 23.12600  20.64200  72.81300  1.000 44.66000 ? 157 ARG A NE  1 
ATOM   1295 C CZ  . ARG A 1 156 ? 23.62800  21.14400  73.93800  1.000 55.15000 ? 157 ARG A CZ  1 
ATOM   1296 N NH1 . ARG A 1 156 ? 24.35900  22.25500  73.92800  1.000 45.87000 ? 157 ARG A NH1 1 
ATOM   1297 N NH2 . ARG A 1 156 ? 23.42900  20.49000  75.09600  1.000 33.11000 ? 157 ARG A NH2 1 
ATOM   1298 N N   . ALA A 1 157 ? 26.42700  16.91500  70.11400  1.000 20.61000 ? 158 ALA A N   1 
ATOM   1299 C CA  . ALA A 1 157 ? 27.81700  16.58100  70.44900  1.000 16.46000 ? 158 ALA A CA  1 
ATOM   1300 C C   . ALA A 1 157 ? 28.61900  16.22000  69.19500  1.000 19.08000 ? 158 ALA A C   1 
ATOM   1301 O O   . ALA A 1 157 ? 29.74000  16.70400  69.00000  1.000 17.33000 ? 158 ALA A O   1 
ATOM   1302 C CB  . ALA A 1 157 ? 27.86000  15.42300  71.43800  1.000 21.23000 ? 158 ALA A CB  1 
ATOM   1303 N N   . TYR A 1 158 ? 28.03800  15.38900  68.31600  1.000 15.88000 ? 159 TYR A N   1 
ATOM   1304 C CA  . TYR A 1 158 ? 28.69300  15.07200  67.03900  1.000 14.40000 ? 159 TYR A CA  1 
ATOM   1305 C C   . TYR A 1 158 ? 28.91100  16.32700  66.16700  1.000 15.30000 ? 159 TYR A C   1 
ATOM   1306 O O   . TYR A 1 158 ? 29.99700  16.55100  65.61700  1.000 16.92000 ? 159 TYR A O   1 
ATOM   1307 C CB  . TYR A 1 158 ? 27.85300  14.03500  66.26300  1.000 17.56000 ? 159 TYR A CB  1 
ATOM   1308 C CG  . TYR A 1 158 ? 28.40700  13.77700  64.84600  1.000 16.61000 ? 159 TYR A CG  1 
ATOM   1309 C CD1 . TYR A 1 158 ? 29.44100  12.84500  64.65200  1.000 16.84000 ? 159 TYR A CD1 1 
ATOM   1310 C CD2 . TYR A 1 158 ? 27.93800  14.49500  63.72900  1.000 15.69000 ? 159 TYR A CD2 1 
ATOM   1311 C CE1 . TYR A 1 158 ? 29.96400  12.60700  63.39000  1.000 13.41000 ? 159 TYR A CE1 1 
ATOM   1312 C CE2 . TYR A 1 158 ? 28.44200  14.24800  62.44400  1.000 12.14000 ? 159 TYR A CE2 1 
ATOM   1313 C CZ  . TYR A 1 158 ? 29.46100  13.28800  62.29400  1.000 15.34000 ? 159 TYR A CZ  1 
ATOM   1314 O OH  . TYR A 1 158 ? 29.99600  13.05600  61.02700  1.000 13.58000 ? 159 TYR A OH  1 
ATOM   1315 N N   . LEU A 1 159 ? 27.85300  17.09200  65.91900  1.000 15.79000 ? 160 LEU A N   1 
ATOM   1316 C CA  . LEU A 1 159 ? 27.98700  18.19200  64.96700  1.000 16.00000 ? 160 LEU A CA  1 
ATOM   1317 C C   . LEU A 1 159 ? 28.92500  19.27600  65.49700  1.000 19.22000 ? 160 LEU A C   1 
ATOM   1318 O O   . LEU A 1 159 ? 29.68000  19.89100  64.73100  1.000 17.03000 ? 160 LEU A O   1 
ATOM   1319 C CB  . LEU A 1 159 ? 26.62300  18.78600  64.67300  1.000 13.94000 ? 160 LEU A CB  1 
ATOM   1320 C CG  . LEU A 1 159 ? 25.69000  17.82800  63.89400  1.000 15.08000 ? 160 LEU A CG  1 
ATOM   1321 C CD1 . LEU A 1 159 ? 24.30900  18.41800  63.86300  1.000 14.43000 ? 160 LEU A CD1 1 
ATOM   1322 C CD2 . LEU A 1 159 ? 26.26000  17.58500  62.49200  1.000 13.91000 ? 160 LEU A CD2 1 
ATOM   1323 N N   . GLU A 1 160 ? 28.87200  19.55400  66.80100  1.000 19.87000 ? 161 GLU A N   1 
ATOM   1324 C CA  . GLU A 1 160 ? 29.73800  20.59300  67.30800  1.000 21.22000 ? 161 GLU A CA  1 
ATOM   1325 C C   . GLU A 1 160 ? 31.12300  20.07000  67.67800  1.000 22.55000 ? 161 GLU A C   1 
ATOM   1326 O O   . GLU A 1 160 ? 32.06200  20.86600  67.82600  1.000 25.87000 ? 161 GLU A O   1 
ATOM   1327 C CB  . GLU A 1 160 ? 29.08700  21.26700  68.52700  1.000 21.48000 ? 161 GLU A CB  1 
ATOM   1328 C CG  . GLU A 1 160 ? 27.81400  21.99400  68.20800  1.000 22.48000 ? 161 GLU A CG  1 
ATOM   1329 C CD  . GLU A 1 160 ? 27.18800  22.71500  69.44900  1.000 33.28000 ? 161 GLU A CD  1 
ATOM   1330 O OE1 . GLU A 1 160 ? 27.68400  22.54900  70.56700  1.000 27.53000 ? 161 GLU A OE1 1 
ATOM   1331 O OE2 . GLU A 1 160 ? 26.19800  23.46000  69.28500  1.000 29.13000 ? 161 GLU A OE2 1 
ATOM   1332 N N   . GLY A 1 161 ? 31.26600  18.76600  67.86900  1.000 19.81000 ? 162 GLY A N   1 
ATOM   1333 C CA  . GLY A 1 161 ? 32.54500  18.20300  68.27800  1.000 19.40000 ? 162 GLY A CA  1 
ATOM   1334 C C   . GLY A 1 161 ? 33.19200  17.39500  67.15300  1.000 19.50000 ? 162 GLY A C   1 
ATOM   1335 O O   . GLY A 1 161 ? 33.95700  17.90700  66.33300  1.000 18.47000 ? 162 GLY A O   1 
ATOM   1336 N N   . THR A 1 162 ? 32.87800  16.10500  67.12800  1.000 18.42000 ? 163 THR A N   1 
ATOM   1337 C CA  . THR A 1 162 ? 33.48000  15.14800  66.20400  1.000 16.50000 ? 163 THR A CA  1 
ATOM   1338 C C   . THR A 1 162 ? 33.52500  15.65000  64.75500  1.000 16.92000 ? 163 THR A C   1 
ATOM   1339 O O   . THR A 1 162 ? 34.54500  15.51700  64.06700  1.000 17.80000 ? 163 THR A O   1 
ATOM   1340 C CB  . THR A 1 162 ? 32.65700  13.86400  66.27800  1.000 21.45000 ? 163 THR A CB  1 
ATOM   1341 O OG1 . THR A 1 162 ? 32.64200  13.41100  67.63100  1.000 23.18000 ? 163 THR A OG1 1 
ATOM   1342 C CG2 . THR A 1 162 ? 33.20000  12.81500  65.33400  1.000 15.46000 ? 163 THR A CG2 1 
ATOM   1343 N N   . CYS A 1 163 ? 32.39700  16.14500  64.24700  1.000 14.40000 ? 164 CYS A N   1 
ATOM   1344 C CA  . CYS A 1 163 ? 32.32800  16.54100  62.83500  1.000 13.12000 ? 164 CYS A CA  1 
ATOM   1345 C C   . CYS A 1 163 ? 33.35600  17.63400  62.53300  1.000 19.47000 ? 164 CYS A C   1 
ATOM   1346 O O   . CYS A 1 163 ? 34.07700  17.57700  61.52500  1.000 14.61000 ? 164 CYS A O   1 
ATOM   1347 C CB  . CYS A 1 163 ? 30.89600  17.01900  62.50400  1.000 18.66000 ? 164 CYS A CB  1 
ATOM   1348 S SG  . CYS A 1 163 ? 30.52300  17.30900  60.69600  1.000 17.64000 ? 164 CYS A SG  1 
ATOM   1349 N N   . VAL A 1 164 ? 33.44800  18.62900  63.42700  1.000 13.17000 ? 165 VAL A N   1 
ATOM   1350 C CA  . VAL A 1 164 ? 34.37700  19.73400  63.23900  1.000 15.18000 ? 165 VAL A CA  1 
ATOM   1351 C C   . VAL A 1 164 ? 35.80800  19.22500  63.35600  1.000 20.55000 ? 165 VAL A C   1 
ATOM   1352 O O   . VAL A 1 164 ? 36.70600  19.57900  62.55700  1.000 15.47000 ? 165 VAL A O   1 
ATOM   1353 C CB  . VAL A 1 164 ? 34.06800  20.84900  64.26500  1.000 19.37000 ? 165 VAL A CB  1 
ATOM   1354 C CG1 . VAL A 1 164 ? 35.23500  21.85000  64.40700  1.000 24.61000 ? 165 VAL A CG1 1 
ATOM   1355 C CG2 . VAL A 1 164 ? 32.79300  21.58000  63.89200  1.000 19.52000 ? 165 VAL A CG2 1 
ATOM   1356 N N   . GLU A 1 165 ? 36.04800  18.40900  64.37700  1.000 16.49000 ? 166 GLU A N   1 
ATOM   1357 C CA  . GLU A 1 165 ? 37.41900  17.98000  64.67200  1.000 23.23000 ? 166 GLU A CA  1 
ATOM   1358 C C   . GLU A 1 165 ? 37.97000  17.17600  63.50500  1.000 23.39000 ? 166 GLU A C   1 
ATOM   1359 O O   . GLU A 1 165 ? 39.10100  17.40900  63.04200  1.000 18.62000 ? 166 GLU A O   1 
ATOM   1360 C CB  . GLU A 1 165 ? 37.44200  17.14100  65.97000  1.000 20.53000 ? 166 GLU A CB  1 
ATOM   1361 C CG  . GLU A 1 165 ? 38.63500  16.16700  66.10100  1.000 18.16000 ? 166 GLU A CG  1 
ATOM   1362 C CD  . GLU A 1 165 ? 38.52900  15.12400  67.21200  1.000 28.13000 ? 166 GLU A CD  1 
ATOM   1363 O OE1 . GLU A 1 165 ? 37.43900  14.95300  67.81900  1.000 30.15000 ? 166 GLU A OE1 1 
ATOM   1364 O OE2 . GLU A 1 165 ? 39.53500  14.42300  67.41800  1.000 33.04000 ? 166 GLU A OE2 1 
ATOM   1365 N N   . TRP A 1 166 ? 37.14400  16.26800  62.95900  1.000 17.70000 ? 167 TRP A N   1 
ATOM   1366 C CA  . TRP A 1 166 ? 37.59500  15.40000  61.86700  1.000 15.91000 ? 167 TRP A CA  1 
ATOM   1367 C C   . TRP A 1 166 ? 37.60200  16.13400  60.53600  1.000 14.47000 ? 167 TRP A C   1 
ATOM   1368 O O   . TRP A 1 166 ? 38.49600  15.88800  59.72300  1.000 15.42000 ? 167 TRP A O   1 
ATOM   1369 C CB  . TRP A 1 166 ? 36.73700  14.10300  61.81200  1.000 14.01000 ? 167 TRP A CB  1 
ATOM   1370 C CG  . TRP A 1 166 ? 37.20600  13.19100  62.90300  1.000 16.15000 ? 167 TRP A CG  1 
ATOM   1371 C CD1 . TRP A 1 166 ? 36.81500  13.22800  64.20400  1.000 15.32000 ? 167 TRP A CD1 1 
ATOM   1372 C CD2 . TRP A 1 166 ? 38.26100  12.23200  62.82100  1.000 15.77000 ? 167 TRP A CD2 1 
ATOM   1373 N NE1 . TRP A 1 166 ? 37.53900  12.32800  64.93600  1.000 18.31000 ? 167 TRP A NE1 1 
ATOM   1374 C CE2 . TRP A 1 166 ? 38.42100  11.68000  64.10900  1.000 19.73000 ? 167 TRP A CE2 1 
ATOM   1375 C CE3 . TRP A 1 166 ? 39.04700  11.75100  61.77800  1.000 16.92000 ? 167 TRP A CE3 1 
ATOM   1376 C CZ2 . TRP A 1 166 ? 39.38600  10.69100  64.39800  1.000 25.31000 ? 167 TRP A CZ2 1 
ATOM   1377 C CZ3 . TRP A 1 166 ? 39.97100  10.71800  62.04000  1.000 18.30000 ? 167 TRP A CZ3 1 
ATOM   1378 C CH2 . TRP A 1 166 ? 40.14300  10.21300  63.34700  1.000 21.16000 ? 167 TRP A CH2 1 
ATOM   1379 N N   . LEU A 1 167 ? 36.65900  17.06000  60.28900  1.000 11.95000 ? 168 LEU A N   1 
ATOM   1380 C CA  . LEU A 1 167 ? 36.81200  17.91700  59.10700  1.000 13.52000 ? 168 LEU A CA  1 
ATOM   1381 C C   . LEU A 1 167 ? 38.15800  18.63600  59.13600  1.000 17.66000 ? 168 LEU A C   1 
ATOM   1382 O O   . LEU A 1 167 ? 38.87700  18.69200  58.12400  1.000 16.10000 ? 168 LEU A O   1 
ATOM   1383 C CB  . LEU A 1 167 ? 35.65700  18.93000  59.00700  1.000 12.61000 ? 168 LEU A CB  1 
ATOM   1384 C CG  . LEU A 1 167 ? 35.69300  20.02900  57.94100  1.000 13.67000 ? 168 LEU A CG  1 
ATOM   1385 C CD1 . LEU A 1 167 ? 35.82400  19.35500  56.58600  1.000 13.65000 ? 168 LEU A CD1 1 
ATOM   1386 C CD2 . LEU A 1 167 ? 34.35900  20.75700  57.95600  1.000 17.02000 ? 168 LEU A CD2 1 
ATOM   1387 N N   . ARG A 1 168 ? 38.51300  19.21800  60.29300  1.000 14.70000 ? 169 ARG A N   1 
ATOM   1388 C CA  . ARG A 1 168 ? 39.79300  19.93800  60.36100  1.000 14.74000 ? 169 ARG A CA  1 
ATOM   1389 C C   . ARG A 1 168 ? 40.97800  19.00100  60.13800  1.000 16.60000 ? 169 ARG A C   1 
ATOM   1390 O O   . ARG A 1 168 ? 41.95000  19.37100  59.45700  1.000 17.27000 ? 169 ARG A O   1 
ATOM   1391 C CB  . ARG A 1 168 ? 39.93500  20.69900  61.69200  1.000 16.07000 ? 169 ARG A CB  1 
ATOM   1392 C CG  . ARG A 1 168 ? 38.83200  21.78100  61.84200  1.000 22.79000 ? 169 ARG A CG  1 
ATOM   1393 C CD  . ARG A 1 168 ? 39.17600  22.98600  62.72800  1.000 38.14000 ? 169 ARG A CD  1 
ATOM   1394 N NE  . ARG A 1 168 ? 39.07400  22.68000  64.14500  1.000 43.03000 ? 169 ARG A NE  1 
ATOM   1395 C CZ  . ARG A 1 168 ? 38.41500  23.39900  65.05600  1.000 50.27000 ? 169 ARG A CZ  1 
ATOM   1396 N NH1 . ARG A 1 168 ? 37.66900  24.45400  64.72300  1.000 44.23000 ? 169 ARG A NH1 1 
ATOM   1397 N NH2 . ARG A 1 168 ? 38.49400  23.04000  66.33900  1.000 42.97000 ? 169 ARG A NH2 1 
ATOM   1398 N N   . ARG A 1 169 ? 40.91100  17.77300  60.66800  1.000 16.09000 ? 170 ARG A N   1 
ATOM   1399 C CA  . ARG A 1 169 ? 41.98800  16.82900  60.41900  1.000 17.31000 ? 170 ARG A CA  1 
ATOM   1400 C C   . ARG A 1 169 ? 42.09300  16.48900  58.93600  1.000 14.58000 ? 170 ARG A C   1 
ATOM   1401 O O   . ARG A 1 169 ? 43.17300  16.50700  58.37400  1.000 17.91000 ? 170 ARG A O   1 
ATOM   1402 C CB  . ARG A 1 169 ? 41.78400  15.57700  61.25700  1.000 19.86000 ? 170 ARG A CB  1 
ATOM   1403 C CG  . ARG A 1 169 ? 42.80100  14.46800  61.00800  1.000 19.83000 ? 170 ARG A CG  1 
ATOM   1404 C CD  . ARG A 1 169 ? 42.23300  13.15800  61.55900  1.000 29.82000 ? 170 ARG A CD  1 
ATOM   1405 N NE  . ARG A 1 169 ? 43.14600  12.03700  61.41900  1.000 23.62000 ? 170 ARG A NE  1 
ATOM   1406 C CZ  . ARG A 1 169 ? 43.88300  11.57000  62.41100  1.000 39.81000 ? 170 ARG A CZ  1 
ATOM   1407 N NH1 . ARG A 1 169 ? 43.85300  12.13100  63.61400  1.000 50.74000 ? 170 ARG A NH1 1 
ATOM   1408 N NH2 . ARG A 1 169 ? 44.62000  10.48000  62.21500  1.000 38.66000 ? 170 ARG A NH2 1 
ATOM   1409 N N   . TYR A 1 170 ? 40.96400  16.18700  58.27600  1.000 17.73000 ? 171 TYR A N   1 
ATOM   1410 C CA  . TYR A 1 170 ? 41.02300  15.89300  56.84600  1.000 17.30000 ? 171 TYR A CA  1 
ATOM   1411 C C   . TYR A 1 170 ? 41.57600  17.06800  56.04400  1.000 17.07000 ? 171 TYR A C   1 
ATOM   1412 O O   . TYR A 1 170 ? 42.30100  16.86700  55.06400  1.000 17.35000 ? 171 TYR A O   1 
ATOM   1413 C CB  . TYR A 1 170 ? 39.62900  15.55800  56.32500  1.000 12.77000 ? 171 TYR A CB  1 
ATOM   1414 C CG  . TYR A 1 170 ? 38.98200  14.33800  56.99100  1.000 13.72000 ? 171 TYR A CG  1 
ATOM   1415 C CD1 . TYR A 1 170 ? 39.75900  13.30400  57.50400  1.000 13.65000 ? 171 TYR A CD1 1 
ATOM   1416 C CD2 . TYR A 1 170 ? 37.57900  14.26400  57.14700  1.000 12.88000 ? 171 TYR A CD2 1 
ATOM   1417 C CE1 . TYR A 1 170 ? 39.13300  12.13300  58.12400  1.000 14.01000 ? 171 TYR A CE1 1 
ATOM   1418 C CE2 . TYR A 1 170 ? 36.94500  13.15100  57.75700  1.000 13.10000 ? 171 TYR A CE2 1 
ATOM   1419 C CZ  . TYR A 1 170 ? 37.73700  12.07200  58.21400  1.000 15.79000 ? 171 TYR A CZ  1 
ATOM   1420 O OH  . TYR A 1 170 ? 37.12600  10.96900  58.81000  1.000 13.07000 ? 171 TYR A OH  1 
ATOM   1421 N N   . LEU A 1 171 ? 41.11900  18.28400  56.35200  1.000 14.91000 ? 172 LEU A N   1 
ATOM   1422 C CA  . LEU A 1 171 ? 41.59700  19.45800  55.63500  1.000 19.02000 ? 172 LEU A CA  1 
ATOM   1423 C C   . LEU A 1 171 ? 43.11700  19.57300  55.70900  1.000 17.94000 ? 172 LEU A C   1 
ATOM   1424 O O   . LEU A 1 171 ? 43.76800  19.93500  54.71700  1.000 18.88000 ? 172 LEU A O   1 
ATOM   1425 C CB  . LEU A 1 171 ? 40.93400  20.72600  56.17600  1.000 14.21000 ? 172 LEU A CB  1 
ATOM   1426 C CG  . LEU A 1 171 ? 39.46200  20.83700  55.75400  1.000 18.31000 ? 172 LEU A CG  1 
ATOM   1427 C CD1 . LEU A 1 171 ? 38.74700  21.90000  56.54800  1.000 15.76000 ? 172 LEU A CD1 1 
ATOM   1428 C CD2 . LEU A 1 171 ? 39.21200  21.10100  54.23000  1.000 17.87000 ? 172 LEU A CD2 1 
ATOM   1429 N N   . GLU A 1 172 ? 43.69300  19.28900  56.88500  1.000 17.38000 ? 173 GLU A N   1 
ATOM   1430 C CA  . GLU A 1 172 ? 45.13600  19.38700  57.05900  1.000 22.10000 ? 173 GLU A CA  1 
ATOM   1431 C C   . GLU A 1 172 ? 45.85900  18.26800  56.30300  1.000 22.43000 ? 173 GLU A C   1 
ATOM   1432 O O   . GLU A 1 172 ? 46.76800  18.52000  55.50100  1.000 22.90000 ? 173 GLU A O   1 
ATOM   1433 C CB  . GLU A 1 172 ? 45.44200  19.33800  58.57700  1.000 19.45000 ? 173 GLU A CB  1 
ATOM   1434 C CG  . GLU A 1 172 ? 46.92300  19.35000  58.96000  1.000 26.55000 ? 173 GLU A CG  1 
ATOM   1435 C CD  . GLU A 1 172 ? 47.63100  20.55100  58.42800  1.000 39.12000 ? 173 GLU A CD  1 
ATOM   1436 O OE1 . GLU A 1 172 ? 46.98400  21.63200  58.25400  1.000 34.77000 ? 173 GLU A OE1 1 
ATOM   1437 O OE2 . GLU A 1 172 ? 48.83500  20.38800  58.11900  1.000 42.45000 ? 173 GLU A OE2 1 
ATOM   1438 N N   . ASN A 1 173 ? 45.42300  17.01500  56.49700  1.000 19.66000 ? 174 ASN A N   1 
ATOM   1439 C CA  . ASN A 1 173 ? 46.07500  15.89800  55.82400  1.000 23.22000 ? 174 ASN A CA  1 
ATOM   1440 C C   . ASN A 1 173 ? 45.92700  15.98300  54.32000  1.000 24.17000 ? 174 ASN A C   1 
ATOM   1441 O O   . ASN A 1 173 ? 46.80400  15.49100  53.57900  1.000 26.75000 ? 174 ASN A O   1 
ATOM   1442 C CB  . ASN A 1 173 ? 45.53800  14.56800  56.37000  1.000 23.41000 ? 174 ASN A CB  1 
ATOM   1443 C CG  . ASN A 1 173 ? 45.95900  14.36300  57.82700  1.000 27.03000 ? 174 ASN A CG  1 
ATOM   1444 O OD1 . ASN A 1 173 ? 46.84300  15.06200  58.31900  1.000 33.64000 ? 174 ASN A OD1 1 
ATOM   1445 N ND2 . ASN A 1 173 ? 45.32000  13.43500  58.52200  1.000 24.99000 ? 174 ASN A ND2 1 
ATOM   1446 N N   . GLY A 1 174 ? 44.84500  16.61200  53.84300  1.000 19.08000 ? 175 GLY A N   1 
ATOM   1447 C CA  . GLY A 1 174 ? 44.62400  16.73100  52.42100  1.000 20.58000 ? 175 GLY A CA  1 
ATOM   1448 C C   . GLY A 1 174 ? 44.77700  18.15600  51.92000  1.000 23.16000 ? 175 GLY A C   1 
ATOM   1449 O O   . GLY A 1 174 ? 44.17600  18.52800  50.93200  1.000 20.98000 ? 175 GLY A O   1 
ATOM   1450 N N   . LYS A 1 175 ? 45.58400  18.98900  52.57800  1.000 22.73000 ? 176 LYS A N   1 
ATOM   1451 C CA  . LYS A 1 175 ? 45.54900  20.39000  52.19200  1.000 21.79000 ? 176 LYS A CA  1 
ATOM   1452 C C   . LYS A 1 175 ? 46.16100  20.63100  50.81800  1.000 19.22000 ? 176 LYS A C   1 
ATOM   1453 O O   . LYS A 1 175 ? 45.79400  21.59300  50.18100  1.000 23.38000 ? 176 LYS A O   1 
ATOM   1454 C CB  . LYS A 1 175 ? 46.28500  21.28000  53.18600  1.000 29.62000 ? 176 LYS A CB  1 
ATOM   1455 C CG  . LYS A 1 175 ? 47.69700  20.96800  53.39100  1.000 28.04000 ? 176 LYS A CG  1 
ATOM   1456 C CD  . LYS A 1 175 ? 48.28700  22.06100  54.36200  1.000 32.82000 ? 176 LYS A CD  1 
ATOM   1457 C CE  . LYS A 1 175 ? 49.64900  21.64900  54.94200  1.000 45.49000 ? 176 LYS A CE  1 
ATOM   1458 N NZ  . LYS A 1 175 ? 50.05200  22.42100  56.19700  1.000 36.55000 ? 176 LYS A NZ  1 
ATOM   1459 N N   . GLU A 1 176 ? 47.07300  19.78800  50.33700  1.000 25.69000 ? 177 GLU A N   1 
ATOM   1460 C CA  . GLU A 1 176 ? 47.63400  20.12700  49.02200  1.000 27.00000 ? 177 GLU A CA  1 
ATOM   1461 C C   . GLU A 1 176 ? 46.62400  19.97500  47.88900  1.000 29.56000 ? 177 GLU A C   1 
ATOM   1462 O O   . GLU A 1 176 ? 46.89100  20.44200  46.77600  1.000 29.17000 ? 177 GLU A O   1 
ATOM   1463 C CB  . GLU A 1 176 ? 48.86300  19.27300  48.67100  1.000 34.52000 ? 177 GLU A CB  1 
ATOM   1464 C CG  . GLU A 1 176 ? 50.04600  19.65300  49.50800  1.000 44.35000 ? 177 GLU A CG  1 
ATOM   1465 C CD  . GLU A 1 176 ? 50.28200  21.15800  49.51400  1.000 44.60000 ? 177 GLU A CD  1 
ATOM   1466 O OE1 . GLU A 1 176 ? 50.25300  21.78100  48.43000  1.000 51.50000 ? 177 GLU A OE1 1 
ATOM   1467 O OE2 . GLU A 1 176 ? 50.41500  21.72600  50.63500  1.000 51.76000 ? 177 GLU A OE2 1 
ATOM   1468 N N   . THR A 1 177 ? 45.49200  19.31900  48.12500  1.000 25.98000 ? 178 THR A N   1 
ATOM   1469 C CA  . THR A 1 177 ? 44.41500  19.26100  47.14600  1.000 22.12000 ? 178 THR A CA  1 
ATOM   1470 C C   . THR A 1 177 ? 43.15400  19.95200  47.62800  1.000 27.23000 ? 178 THR A C   1 
ATOM   1471 O O   . THR A 1 177 ? 42.47400  20.58000  46.83100  1.000 28.64000 ? 178 THR A O   1 
ATOM   1472 C CB  . THR A 1 177 ? 44.06900  17.80500  46.75900  1.000 24.07000 ? 178 THR A CB  1 
ATOM   1473 O OG1 . THR A 1 177 ? 43.94200  16.99800  47.93400  1.000 29.95000 ? 178 THR A OG1 1 
ATOM   1474 C CG2 . THR A 1 177 ? 45.15900  17.22200  45.88200  1.000 27.84000 ? 178 THR A CG2 1 
ATOM   1475 N N   . LEU A 1 178 ? 42.80400  19.83500  48.91900  1.000 24.08000 ? 179 LEU A N   1 
ATOM   1476 C CA  . LEU A 1 178 ? 41.54000  20.38900  49.38300  1.000 19.21000 ? 179 LEU A CA  1 
ATOM   1477 C C   . LEU A 1 178 ? 41.60200  21.86600  49.60400  1.000 23.27000 ? 179 LEU A C   1 
ATOM   1478 O O   . LEU A 1 178 ? 40.55500  22.52800  49.59300  1.000 24.28000 ? 179 LEU A O   1 
ATOM   1479 C CB  . LEU A 1 178 ? 41.09500  19.76400  50.71900  1.000 17.51000 ? 179 LEU A CB  1 
ATOM   1480 C CG  . LEU A 1 178 ? 40.86100  18.24400  50.62000  1.000 18.99000 ? 179 LEU A CG  1 
ATOM   1481 C CD1 . LEU A 1 178 ? 40.64300  17.68800  52.08300  1.000 18.18000 ? 179 LEU A CD1 1 
ATOM   1482 C CD2 . LEU A 1 178 ? 39.70000  17.90300  49.67900  1.000 17.14000 ? 179 LEU A CD2 1 
ATOM   1483 N N   . GLN A 1 179 ? 42.77800  22.38300  49.93200  1.000 20.95000 ? 180 GLN A N   1 
ATOM   1484 C CA  . GLN A 1 179 ? 42.89500  23.79500  50.22200  1.000 20.73000 ? 180 GLN A CA  1 
ATOM   1485 C C   . GLN A 1 179 ? 43.69400  24.50900  49.16200  1.000 25.74000 ? 180 GLN A C   1 
ATOM   1486 O O   . GLN A 1 179 ? 44.21700  25.58100  49.43300  1.000 24.54000 ? 180 GLN A O   1 
ATOM   1487 C CB  . GLN A 1 179 ? 43.52900  24.03100  51.61000  1.000 23.13000 ? 180 GLN A CB  1 
ATOM   1488 C CG  . GLN A 1 179 ? 42.73200  23.44300  52.78700  1.000 20.16000 ? 180 GLN A CG  1 
ATOM   1489 C CD  . GLN A 1 179 ? 43.24100  23.94600  54.16500  1.000 25.17000 ? 180 GLN A CD  1 
ATOM   1490 O OE1 . GLN A 1 179 ? 43.07800  25.09500  54.52300  1.000 31.69000 ? 180 GLN A OE1 1 
ATOM   1491 N NE2 . GLN A 1 179 ? 43.82800  23.05900  54.91800  1.000 23.77000 ? 180 GLN A NE2 1 
ATOM   1492 N N   . ARG A 1 180 ? 43.81400  23.94100  47.96200  1.000 22.49000 ? 181 ARG A N   1 
ATOM   1493 C CA  . ARG A 1 180 ? 44.53100  24.62600  46.87300  1.000 30.64000 ? 181 ARG A CA  1 
ATOM   1494 C C   . ARG A 1 180 ? 43.66400  24.51400  45.60600  1.000 23.29000 ? 181 ARG A C   1 
ATOM   1495 O O   . ARG A 1 180 ? 43.70800  23.50200  44.89800  1.000 26.83000 ? 181 ARG A O   1 
ATOM   1496 C CB  . ARG A 1 180 ? 45.98000  24.05500  46.69800  1.000 27.39000 ? 181 ARG A CB  1 
ATOM   1497 C CG  . ARG A 1 180 ? 46.47000  23.79900  45.28100  0.000 29.19000 ? 181 ARG A CG  1 
ATOM   1498 C CD  . ARG A 1 180 ? 47.96400  23.52800  45.19800  0.000 31.20000 ? 181 ARG A CD  1 
ATOM   1499 N NE  . ARG A 1 180 ? 48.73000  24.76900  45.24200  0.000 31.68000 ? 181 ARG A NE  1 
ATOM   1500 C CZ  . ARG A 1 180 ? 48.79200  25.64500  44.24700  0.000 31.60000 ? 181 ARG A CZ  1 
ATOM   1501 N NH1 . ARG A 1 180 ? 48.16000  25.43800  43.10200  0.000 31.97000 ? 181 ARG A NH1 1 
ATOM   1502 N NH2 . ARG A 1 180 ? 49.50200  26.75800  44.40500  0.000 30.99000 ? 181 ARG A NH2 1 
ATOM   1503 N N   . ALA A 1 181 ? 42.83900  25.53100  45.37900  1.000 21.66000 ? 182 ALA A N   1 
ATOM   1504 C CA  . ALA A 1 181 ? 41.87800  25.49800  44.27800  1.000 20.44000 ? 182 ALA A CA  1 
ATOM   1505 C C   . ALA A 1 181 ? 42.61000  25.40500  42.95600  1.000 27.12000 ? 182 ALA A C   1 
ATOM   1506 O O   . ALA A 1 181 ? 43.64400  26.04900  42.78100  1.000 20.81000 ? 182 ALA A O   1 
ATOM   1507 C CB  . ALA A 1 181 ? 40.99800  26.75800  44.28500  1.000 22.23000 ? 182 ALA A CB  1 
ATOM   1508 N N   . GLU A 1 182 ? 42.10000  24.55800  42.03300  1.000 22.19000 ? 183 GLU A N   1 
ATOM   1509 C CA  . GLU A 1 182 ? 42.71300  24.38100  40.71200  1.000 20.30000 ? 183 GLU A CA  1 
ATOM   1510 C C   . GLU A 1 182 ? 41.92000  25.20800  39.70800  1.000 17.86000 ? 183 GLU A C   1 
ATOM   1511 O O   . GLU A 1 182 ? 40.71300  24.96700  39.53700  1.000 16.41000 ? 183 GLU A O   1 
ATOM   1512 C CB  . GLU A 1 182 ? 42.73600  22.90600  40.31800  1.000 21.29000 ? 183 GLU A CB  1 
ATOM   1513 C CG  . GLU A 1 182 ? 43.36200  22.69500  38.93100  1.000 20.58000 ? 183 GLU A CG  1 
ATOM   1514 C CD  . GLU A 1 182 ? 44.86700  22.96200  38.95700  1.000 47.25000 ? 183 GLU A CD  1 
ATOM   1515 O OE1 . GLU A 1 182 ? 45.51200  22.62800  39.98000  1.000 43.35000 ? 183 GLU A OE1 1 
ATOM   1516 O OE2 . GLU A 1 182 ? 45.39800  23.56400  37.99200  1.000 54.17000 ? 183 GLU A OE2 1 
ATOM   1517 N N   . HIS A 1 183 ? 42.57400  26.23400  39.09500  1.000 18.76000 ? 184 HIS A N   1 
ATOM   1518 C CA  . HIS A 1 183 ? 41.85400  27.16100  38.21800  1.000 22.11000 ? 184 HIS A CA  1 
ATOM   1519 C C   . HIS A 1 183 ? 41.43100  26.45600  36.92000  1.000 16.82000 ? 184 HIS A C   1 
ATOM   1520 O O   . HIS A 1 183 ? 42.04000  25.45600  36.52100  1.000 18.94000 ? 184 HIS A O   1 
ATOM   1521 C CB  . HIS A 1 183 ? 42.74200  28.36700  37.89700  1.000 19.52000 ? 184 HIS A CB  1 
ATOM   1522 C CG  . HIS A 1 183 ? 43.92900  27.99400  37.06500  1.000 23.83000 ? 184 HIS A CG  1 
ATOM   1523 N ND1 . HIS A 1 183 ? 45.08700  27.49400  37.62700  1.000 26.33000 ? 184 HIS A ND1 1 
ATOM   1524 C CD2 . HIS A 1 183 ? 44.15800  28.06400  35.73300  1.000 25.80000 ? 184 HIS A CD2 1 
ATOM   1525 C CE1 . HIS A 1 183 ? 45.95700  27.22300  36.67100  1.000 26.97000 ? 184 HIS A CE1 1 
ATOM   1526 N NE2 . HIS A 1 183 ? 45.42400  27.56900  35.51200  1.000 27.69000 ? 184 HIS A NE2 1 
ATOM   1527 N N   . PRO A 1 184 ? 40.35700  26.92000  36.28200  1.000 14.86000 ? 185 PRO A N   1 
ATOM   1528 C CA  . PRO A 1 184 ? 39.92000  26.30600  35.01700  1.000 14.53000 ? 185 PRO A CA  1 
ATOM   1529 C C   . PRO A 1 184 ? 40.91800  26.63200  33.91500  1.000 17.76000 ? 185 PRO A C   1 
ATOM   1530 O O   . PRO A 1 184 ? 41.40000  27.76700  33.82300  1.000 20.25000 ? 185 PRO A O   1 
ATOM   1531 C CB  . PRO A 1 184 ? 38.55700  26.98600  34.72600  1.000 14.80000 ? 185 PRO A CB  1 
ATOM   1532 C CG  . PRO A 1 184 ? 38.65900  28.32300  35.47000  1.000 14.78000 ? 185 PRO A CG  1 
ATOM   1533 C CD  . PRO A 1 184 ? 39.45600  28.02500  36.70000  1.000 17.93000 ? 185 PRO A CD  1 
ATOM   1534 N N   . LYS A 1 185 ? 41.24000  25.63000  33.10400  1.000 16.32000 ? 186 LYS A N   1 
ATOM   1535 C CA  . LYS A 1 185 ? 41.89600  25.89500  31.82800  1.000 16.57000 ? 186 LYS A CA  1 
ATOM   1536 C C   . LYS A 1 185 ? 40.80200  26.33900  30.86300  1.000 16.96000 ? 186 LYS A C   1 
ATOM   1537 O O   . LYS A 1 185 ? 39.79400  25.63600  30.70200  1.000 16.25000 ? 186 LYS A O   1 
ATOM   1538 C CB  . LYS A 1 185 ? 42.55700  24.63000  31.30400  1.000 22.75000 ? 186 LYS A CB  1 
ATOM   1539 C CG  . LYS A 1 185 ? 43.55700  23.99200  32.27400  1.000 25.46000 ? 186 LYS A CG  1 
ATOM   1540 C CD  . LYS A 1 185 ? 44.15200  24.92800  33.28300  1.000 29.09000 ? 186 LYS A CD  1 
ATOM   1541 C CE  . LYS A 1 185 ? 44.96100  24.13200  34.33800  1.000 38.73000 ? 186 LYS A CE  1 
ATOM   1542 N NZ  . LYS A 1 185 ? 44.21900  24.06400  35.69000  1.000 27.28000 ? 186 LYS A NZ  1 
ATOM   1543 N N   . THR A 1 186 ? 40.97800  27.47900  30.21700  1.000 17.36000 ? 187 THR A N   1 
ATOM   1544 C CA  . THR A 1 186 ? 39.91500  28.06000  29.41700  1.000 14.43000 ? 187 THR A CA  1 
ATOM   1545 C C   . THR A 1 186 ? 40.34200  28.24800  27.96800  1.000 21.86000 ? 187 THR A C   1 
ATOM   1546 O O   . THR A 1 186 ? 41.52400  28.47900  27.66100  1.000 17.81000 ? 187 THR A O   1 
ATOM   1547 C CB  . THR A 1 186 ? 39.50800  29.41200  29.99600  1.000 21.32000 ? 187 THR A CB  1 
ATOM   1548 O OG1 . THR A 1 186 ? 40.68300  30.22000  30.10300  1.000 17.97000 ? 187 THR A OG1 1 
ATOM   1549 C CG2 . THR A 1 186 ? 38.94100  29.25900  31.38800  1.000 17.63000 ? 187 THR A CG2 1 
ATOM   1550 N N   . HIS A 1 187 ? 39.36100  28.15300  27.07900  1.000 16.88000 ? 188 HIS A N   1 
ATOM   1551 C CA  . HIS A 1 187 ? 39.56600  28.58000  25.70400  1.000 16.83000 ? 188 HIS A CA  1 
ATOM   1552 C C   . HIS A 1 187 ? 38.19900  28.82400  25.06600  1.000 17.84000 ? 188 HIS A C   1 
ATOM   1553 O O   . HIS A 1 187 ? 37.15400  28.44500  25.61700  1.000 14.70000 ? 188 HIS A O   1 
ATOM   1554 C CB  . HIS A 1 187 ? 40.40900  27.53500  24.96100  1.000 18.31000 ? 188 HIS A CB  1 
ATOM   1555 C CG  . HIS A 1 187 ? 39.67700  26.26200  24.74100  1.000 19.02000 ? 188 HIS A CG  1 
ATOM   1556 N ND1 . HIS A 1 187 ? 39.60100  25.28300  25.71700  1.000 17.86000 ? 188 HIS A ND1 1 
ATOM   1557 C CD2 . HIS A 1 187 ? 39.03100  25.77000  23.65900  1.000 22.29000 ? 188 HIS A CD2 1 
ATOM   1558 C CE1 . HIS A 1 187 ? 38.89200  24.26600  25.25500  1.000 21.19000 ? 188 HIS A CE1 1 
ATOM   1559 N NE2 . HIS A 1 187 ? 38.55000  24.52600  24.00700  1.000 24.57000 ? 188 HIS A NE2 1 
ATOM   1560 N N   . VAL A 1 188 ? 38.20900  29.52300  23.93200  1.000 13.37000 ? 189 VAL A N   1 
ATOM   1561 C CA  . VAL A 1 188 ? 36.99800  29.74900  23.13200  1.000 15.30000 ? 189 VAL A CA  1 
ATOM   1562 C C   . VAL A 1 188 ? 37.10100  28.98700  21.82700  1.000 18.02000 ? 189 VAL A C   1 
ATOM   1563 O O   . VAL A 1 188 ? 38.12500  29.08500  21.14300  1.000 19.24000 ? 189 VAL A O   1 
ATOM   1564 C CB  . VAL A 1 188 ? 36.80400  31.24100  22.83500  1.000 16.49000 ? 189 VAL A CB  1 
ATOM   1565 C CG1 . VAL A 1 188 ? 35.64100  31.37900  21.84700  1.000 16.17000 ? 189 VAL A CG1 1 
ATOM   1566 C CG2 . VAL A 1 188 ? 36.60100  32.07600  24.18200  1.000 16.78000 ? 189 VAL A CG2 1 
ATOM   1567 N N   . THR A 1 189 ? 36.05000  28.26000  21.44400  1.000 15.58000 ? 190 THR A N   1 
ATOM   1568 C CA  . THR A 1 189 ? 36.03700  27.62200  20.13000  1.000 13.60000 ? 190 THR A CA  1 
ATOM   1569 C C   . THR A 1 189 ? 34.94900  28.25100  19.27200  1.000 21.04000 ? 190 THR A C   1 
ATOM   1570 O O   . THR A 1 189 ? 33.97000  28.78900  19.78300  1.000 22.49000 ? 190 THR A O   1 
ATOM   1571 C CB  . THR A 1 189 ? 35.77500  26.11200  20.23000  1.000 22.20000 ? 190 THR A CB  1 
ATOM   1572 O OG1 . THR A 1 189 ? 34.59000  25.91000  20.99800  1.000 25.90000 ? 190 THR A OG1 1 
ATOM   1573 C CG2 . THR A 1 189 ? 36.87500  25.33800  20.92200  1.000 15.21000 ? 190 THR A CG2 1 
ATOM   1574 N N   . HIS A 1 190 ? 35.10200  28.15200  17.95000  1.000 18.15000 ? 191 HIS A N   1 
ATOM   1575 C CA  . HIS A 1 190 ? 34.23700  28.80400  16.96500  1.000 20.46000 ? 191 HIS A CA  1 
ATOM   1576 C C   . HIS A 1 190 ? 33.73400  27.71400  16.01500  1.000 23.59000 ? 191 HIS A C   1 
ATOM   1577 O O   . HIS A 1 190 ? 34.50800  26.84400  15.60400  1.000 22.88000 ? 191 HIS A O   1 
ATOM   1578 C CB  . HIS A 1 190 ? 35.07800  29.85500  16.22800  1.000 20.79000 ? 191 HIS A CB  1 
ATOM   1579 C CG  . HIS A 1 190 ? 34.34400  30.69500  15.23700  1.000 21.84000 ? 191 HIS A CG  1 
ATOM   1580 N ND1 . HIS A 1 190 ? 34.07100  30.24600  13.96100  1.000 26.41000 ? 191 HIS A ND1 1 
ATOM   1581 C CD2 . HIS A 1 190 ? 34.01700  32.00300  15.24400  1.000 25.61000 ? 191 HIS A CD2 1 
ATOM   1582 C CE1 . HIS A 1 190 ? 33.50500  31.21800  13.26100  1.000 23.60000 ? 191 HIS A CE1 1 
ATOM   1583 N NE2 . HIS A 1 190 ? 33.45600  32.29700  14.01300  1.000 28.02000 ? 191 HIS A NE2 1 
ATOM   1584 N N   . HIS A 1 191 ? 32.43100  27.70600  15.73100  1.000 24.06000 ? 192 HIS A N   1 
ATOM   1585 C CA  . HIS A 1 191 ? 31.78200  26.62100  14.98000  1.000 27.87000 ? 192 HIS A CA  1 
ATOM   1586 C C   . HIS A 1 191 ? 30.80600  27.28500  14.01900  1.000 28.31000 ? 192 HIS A C   1 
ATOM   1587 O O   . HIS A 1 191 ? 29.68600  27.66400  14.41400  1.000 24.81000 ? 192 HIS A O   1 
ATOM   1588 C CB  . HIS A 1 191 ? 31.00200  25.66200  15.88700  1.000 29.87000 ? 192 HIS A CB  1 
ATOM   1589 C CG  . HIS A 1 191 ? 31.81700  25.03700  16.97700  1.000 30.77000 ? 192 HIS A CG  1 
ATOM   1590 N ND1 . HIS A 1 191 ? 32.55800  23.89300  16.78200  1.000 25.80000 ? 192 HIS A ND1 1 
ATOM   1591 C CD2 . HIS A 1 191 ? 31.99200  25.38400  18.27900  1.000 27.32000 ? 192 HIS A CD2 1 
ATOM   1592 C CE1 . HIS A 1 191 ? 33.15600  23.55700  17.91300  1.000 26.09000 ? 192 HIS A CE1 1 
ATOM   1593 N NE2 . HIS A 1 191 ? 32.82000  24.44000  18.83600  1.000 26.21000 ? 192 HIS A NE2 1 
ATOM   1594 N N   . PRO A 1 192 ? 31.23000  27.56300  12.79200  1.000 27.16000 ? 193 PRO A N   1 
ATOM   1595 C CA  . PRO A 1 192 ? 30.33200  28.28500  11.89800  1.000 24.74000 ? 193 PRO A CA  1 
ATOM   1596 C C   . PRO A 1 192 ? 29.10200  27.43300  11.71100  1.000 31.94000 ? 193 PRO A C   1 
ATOM   1597 O O   . PRO A 1 192 ? 29.19100  26.20400  11.65100  1.000 31.96000 ? 193 PRO A O   1 
ATOM   1598 C CB  . PRO A 1 192 ? 31.13400  28.41200  10.60100  1.000 30.74000 ? 193 PRO A CB  1 
ATOM   1599 C CG  . PRO A 1 192 ? 32.57200  28.30100  11.03800  1.000 29.28000 ? 193 PRO A CG  1 
ATOM   1600 C CD  . PRO A 1 192 ? 32.53200  27.28700  12.15300  1.000 30.48000 ? 193 PRO A CD  1 
ATOM   1601 N N   . VAL A 1 193 ? 27.93800  28.06800  11.66800  1.000 31.07000 ? 194 VAL A N   1 
ATOM   1602 C CA  . VAL A 1 193 ? 26.73300  27.32100  11.36600  1.000 35.93000 ? 194 VAL A CA  1 
ATOM   1603 C C   . VAL A 1 193 ? 26.20900  27.63500  9.96700   1.000 36.16000 ? 194 VAL A C   1 
ATOM   1604 O O   . VAL A 1 193 ? 25.67100  26.73900  9.30300   1.000 39.69000 ? 194 VAL A O   1 
ATOM   1605 C CB  . VAL A 1 193 ? 25.64600  27.53200  12.43900  1.000 37.05000 ? 194 VAL A CB  1 
ATOM   1606 C CG1 . VAL A 1 193 ? 26.16100  27.05100  13.78100  1.000 30.39000 ? 194 VAL A CG1 1 
ATOM   1607 C CG2 . VAL A 1 193 ? 25.28700  28.95300  12.53900  1.000 37.65000 ? 194 VAL A CG2 1 
ATOM   1608 N N   . SER A 1 194 ? 26.46800  28.83300  9.46800   1.000 33.24000 ? 195 SER A N   1 
ATOM   1609 C CA  . SER A 1 194 ? 26.12200  29.23600  8.12200   1.000 50.16000 ? 195 SER A CA  1 
ATOM   1610 C C   . SER A 1 194 ? 27.18600  30.22400  7.67900   1.000 49.45000 ? 195 SER A C   1 
ATOM   1611 O O   . SER A 1 194 ? 28.02400  30.65600  8.47500   1.000 39.00000 ? 195 SER A O   1 
ATOM   1612 C CB  . SER A 1 194 ? 24.75100  29.90200  8.08600   1.000 40.42000 ? 195 SER A CB  1 
ATOM   1613 O OG  . SER A 1 194 ? 24.89900  31.25900  8.49000   1.000 41.23000 ? 195 SER A OG  1 
ATOM   1614 N N   . ASP A 1 195 ? 27.11500  30.64200  6.41800   1.000 44.35000 ? 196 ASP A N   1 
ATOM   1615 C CA  . ASP A 1 195 ? 27.96200  31.75000  6.00600   1.000 46.92000 ? 196 ASP A CA  1 
ATOM   1616 C C   . ASP A 1 195 ? 27.81400  32.96400  6.90900   1.000 43.76000 ? 196 ASP A C   1 
ATOM   1617 O O   . ASP A 1 195 ? 28.74900  33.78000  6.98300   1.000 42.25000 ? 196 ASP A O   1 
ATOM   1618 C CB  . ASP A 1 195 ? 27.68300  32.15300  4.54600   0.000 53.78000 ? 196 ASP A CB  1 
ATOM   1619 C CG  . ASP A 1 195 ? 28.05800  31.05800  3.57300   0.000 62.30000 ? 196 ASP A CG  1 
ATOM   1620 O OD1 . ASP A 1 195 ? 28.68400  30.07300  4.04500   0.000 62.91000 ? 196 ASP A OD1 1 
ATOM   1621 O OD2 . ASP A 1 195 ? 27.79000  31.20800  2.35300   0.000 60.09000 ? 196 ASP A OD2 1 
ATOM   1622 N N   . HIS A 1 196 ? 26.69500  33.09200  7.62600   1.000 41.54000 ? 197 HIS A N   1 
ATOM   1623 C CA  . HIS A 1 196 ? 26.42800  34.34700  8.29800   1.000 48.19000 ? 197 HIS A CA  1 
ATOM   1624 C C   . HIS A 1 196 ? 26.35100  34.27200  9.82700   1.000 39.12000 ? 197 HIS A C   1 
ATOM   1625 O O   . HIS A 1 196 ? 26.38300  35.32100  10.47000  1.000 31.81000 ? 197 HIS A O   1 
ATOM   1626 C CB  . HIS A 1 196 ? 25.15900  34.98600  7.70900   1.000 37.73000 ? 197 HIS A CB  1 
ATOM   1627 C CG  . HIS A 1 196 ? 25.26000  35.20900  6.21700   1.000 45.76000 ? 197 HIS A CG  1 
ATOM   1628 N ND1 . HIS A 1 196 ? 26.28700  35.93600  5.63900   1.000 38.05000 ? 197 HIS A ND1 1 
ATOM   1629 C CD2 . HIS A 1 196 ? 24.48300  34.77600  5.18800   1.000 40.03000 ? 197 HIS A CD2 1 
ATOM   1630 C CE1 . HIS A 1 196 ? 26.14300  35.93800  4.32000   1.000 31.32000 ? 197 HIS A CE1 1 
ATOM   1631 N NE2 . HIS A 1 196 ? 25.06300  35.23400  4.02100   1.000 36.76000 ? 197 HIS A NE2 1 
ATOM   1632 N N   . GLU A 1 197 ? 26.34900  33.10200  10.44300  1.000 35.73000 ? 198 GLU A N   1 
ATOM   1633 C CA  . GLU A 1 197 ? 26.54700  33.15500  11.88500  1.000 37.20000 ? 198 GLU A CA  1 
ATOM   1634 C C   . GLU A 1 197 ? 27.32700  31.93000  12.36100  1.000 30.62000 ? 198 GLU A C   1 
ATOM   1635 O O   . GLU A 1 197 ? 27.56200  30.97700  11.61400  1.000 33.17000 ? 198 GLU A O   1 
ATOM   1636 C CB  . GLU A 1 197 ? 25.19200  33.36600  12.58600  1.000 35.26000 ? 198 GLU A CB  1 
ATOM   1637 C CG  . GLU A 1 197 ? 24.43900  32.13200  12.75300  1.000 44.27000 ? 198 GLU A CG  1 
ATOM   1638 C CD  . GLU A 1 197 ? 22.93600  32.32300  12.99900  1.000 43.79000 ? 198 GLU A CD  1 
ATOM   1639 O OE1 . GLU A 1 197 ? 22.47200  33.41700  13.40500  1.000 42.22000 ? 198 GLU A OE1 1 
ATOM   1640 O OE2 . GLU A 1 197 ? 22.24200  31.31900  12.77100  1.000 43.02000 ? 198 GLU A OE2 1 
ATOM   1641 N N   . ALA A 1 198 ? 27.77900  31.99100  13.61800  1.000 29.17000 ? 199 ALA A N   1 
ATOM   1642 C CA  . ALA A 1 198 ? 28.69100  30.99300  14.16800  1.000 29.08000 ? 199 ALA A CA  1 
ATOM   1643 C C   . ALA A 1 198 ? 28.47000  30.91900  15.67000  1.000 24.03000 ? 199 ALA A C   1 
ATOM   1644 O O   . ALA A 1 198 ? 28.13100  31.92000  16.30300  1.000 24.89000 ? 199 ALA A O   1 
ATOM   1645 C CB  . ALA A 1 198 ? 30.17000  31.34200  13.89700  1.000 23.27000 ? 199 ALA A CB  1 
ATOM   1646 N N   . THR A 1 199 ? 28.67800  29.73600  16.22000  1.000 19.40000 ? 200 THR A N   1 
ATOM   1647 C CA  . THR A 1 199 ? 28.61900  29.56500  17.65900  1.000 19.09000 ? 200 THR A CA  1 
ATOM   1648 C C   . THR A 1 199 ? 29.98800  29.83200  18.25600  1.000 24.52000 ? 200 THR A C   1 
ATOM   1649 O O   . THR A 1 199 ? 30.97300  29.24300  17.80300  1.000 23.59000 ? 200 THR A O   1 
ATOM   1650 C CB  . THR A 1 199 ? 28.22000  28.14500  18.00400  1.000 27.64000 ? 200 THR A CB  1 
ATOM   1651 O OG1 . THR A 1 199 ? 26.92400  27.85400  17.47200  1.000 26.97000 ? 200 THR A OG1 1 
ATOM   1652 C CG2 . THR A 1 199 ? 28.24900  27.95300  19.52100  1.000 23.02000 ? 200 THR A CG2 1 
ATOM   1653 N N   . LEU A 1 200 ? 30.05100  30.67100  19.28600  1.000 17.52000 ? 201 LEU A N   1 
ATOM   1654 C CA  . LEU A 1 200 ? 31.26200  30.80100  20.08600  1.000 19.72000 ? 201 LEU A CA  1 
ATOM   1655 C C   . LEU A 1 200 ? 30.99800  30.03000  21.36600  1.000 20.44000 ? 201 LEU A C   1 
ATOM   1656 O O   . LEU A 1 200 ? 30.02400  30.33500  22.05700  1.000 17.83000 ? 201 LEU A O   1 
ATOM   1657 C CB  . LEU A 1 200 ? 31.55600  32.25700  20.40700  1.000 17.37000 ? 201 LEU A CB  1 
ATOM   1658 C CG  . LEU A 1 200 ? 31.93200  33.19600  19.26100  1.000 23.78000 ? 201 LEU A CG  1 
ATOM   1659 C CD1 . LEU A 1 200 ? 32.19100  34.60900  19.72800  1.000 24.03000 ? 201 LEU A CD1 1 
ATOM   1660 C CD2 . LEU A 1 200 ? 33.10600  32.67600  18.48000  1.000 25.19000 ? 201 LEU A CD2 1 
ATOM   1661 N N   . ARG A 1 201 ? 31.86500  29.05900  21.70000  1.000 17.37000 ? 202 ARG A N   1 
ATOM   1662 C CA  . ARG A 1 201 ? 31.70400  28.25000  22.90400  1.000 16.48000 ? 202 ARG A CA  1 
ATOM   1663 C C   . ARG A 1 201 ? 32.89300  28.50800  23.83500  1.000 19.54000 ? 202 ARG A C   1 
ATOM   1664 O O   . ARG A 1 201 ? 34.05800  28.34300  23.43400  1.000 16.31000 ? 202 ARG A O   1 
ATOM   1665 C CB  . ARG A 1 201 ? 31.57300  26.77100  22.56900  1.000 16.29000 ? 202 ARG A CB  1 
ATOM   1666 C CG  . ARG A 1 201 ? 31.32200  25.91200  23.80900  1.000 17.22000 ? 202 ARG A CG  1 
ATOM   1667 C CD  . ARG A 1 201 ? 30.92400  24.50300  23.45400  1.000 19.33000 ? 202 ARG A CD  1 
ATOM   1668 N NE  . ARG A 1 201 ? 29.55100  24.43500  22.95500  1.000 19.08000 ? 202 ARG A NE  1 
ATOM   1669 C CZ  . ARG A 1 201 ? 29.22600  24.08900  21.72800  1.000 26.35000 ? 202 ARG A CZ  1 
ATOM   1670 N NH1 . ARG A 1 201 ? 30.15500  23.75100  20.82700  1.000 27.08000 ? 202 ARG A NH1 1 
ATOM   1671 N NH2 . ARG A 1 201 ? 27.95200  24.14400  21.36900  1.000 22.08000 ? 202 ARG A NH2 1 
ATOM   1672 N N   . CYS A 1 202 ? 32.60200  28.95200  25.06000  1.000 15.81000 ? 203 CYS A N   1 
ATOM   1673 C CA  . CYS A 1 202 ? 33.63700  29.23300  26.07200  1.000 14.00000 ? 203 CYS A CA  1 
ATOM   1674 C C   . CYS A 1 202 ? 33.74400  28.05500  27.02500  1.000 16.86000 ? 203 CYS A C   1 
ATOM   1675 O O   . CYS A 1 202 ? 32.75200  27.68400  27.66600  1.000 15.61000 ? 203 CYS A O   1 
ATOM   1676 C CB  . CYS A 1 202 ? 33.27900  30.50900  26.83600  1.000 15.42000 ? 203 CYS A CB  1 
ATOM   1677 S SG  . CYS A 1 202 ? 34.55300  31.07700  27.92500  1.000 20.34000 ? 203 CYS A SG  1 
ATOM   1678 N N   . TRP A 1 203 ? 34.95600  27.48900  27.13600  1.000 13.55000 ? 204 TRP A N   1 
ATOM   1679 C CA  . TRP A 1 203 ? 35.20600  26.25600  27.85700  1.000 14.76000 ? 204 TRP A CA  1 
ATOM   1680 C C   . TRP A 1 203 ? 35.96800  26.53600  29.14100  1.000 15.53000 ? 204 TRP A C   1 
ATOM   1681 O O   . TRP A 1 203 ? 36.91400  27.32700  29.13300  1.000 14.08000 ? 204 TRP A O   1 
ATOM   1682 C CB  . TRP A 1 203 ? 36.05700  25.27800  27.03300  1.000 14.45000 ? 204 TRP A CB  1 
ATOM   1683 C CG  . TRP A 1 203 ? 35.35400  24.59000  25.94700  1.000 14.87000 ? 204 TRP A CG  1 
ATOM   1684 C CD1 . TRP A 1 203 ? 35.19100  25.00200  24.65300  1.000 16.34000 ? 204 TRP A CD1 1 
ATOM   1685 C CD2 . TRP A 1 203 ? 34.67200  23.32400  26.06200  1.000 15.37000 ? 204 TRP A CD2 1 
ATOM   1686 N NE1 . TRP A 1 203 ? 34.42900  24.06300  23.95900  1.000 16.07000 ? 204 TRP A NE1 1 
ATOM   1687 C CE2 . TRP A 1 203 ? 34.12300  23.02400  24.81000  1.000 16.37000 ? 204 TRP A CE2 1 
ATOM   1688 C CE3 . TRP A 1 203 ? 34.50400  22.40900  27.11400  1.000 16.58000 ? 204 TRP A CE3 1 
ATOM   1689 C CZ2 . TRP A 1 203 ? 33.41800  21.83500  24.57100  1.000 19.66000 ? 204 TRP A CZ2 1 
ATOM   1690 C CZ3 . TRP A 1 203 ? 33.82400  21.24300  26.87900  1.000 19.21000 ? 204 TRP A CZ3 1 
ATOM   1691 C CH2 . TRP A 1 203 ? 33.26900  20.96500  25.60200  1.000 16.53000 ? 204 TRP A CH2 1 
ATOM   1692 N N   . ALA A 1 204 ? 35.59600  25.81800  30.21800  1.000 14.27000 ? 205 ALA A N   1 
ATOM   1693 C CA  . ALA A 1 204 ? 36.28600  25.83500  31.50600  1.000 16.64000 ? 205 ALA A CA  1 
ATOM   1694 C C   . ALA A 1 204 ? 36.53500  24.37400  31.80400  1.000 13.57000 ? 205 ALA A C   1 
ATOM   1695 O O   . ALA A 1 204 ? 35.57200  23.62600  31.97600  1.000 15.36000 ? 205 ALA A O   1 
ATOM   1696 C CB  . ALA A 1 204 ? 35.42900  26.46900  32.62500  1.000 12.87000 ? 205 ALA A CB  1 
ATOM   1697 N N   . LEU A 1 205 ? 37.79000  23.95000  31.86400  1.000 14.34000 ? 206 LEU A N   1 
ATOM   1698 C CA  . LEU A 1 205 ? 38.10100  22.53300  32.09700  1.000 13.61000 ? 206 LEU A CA  1 
ATOM   1699 C C   . LEU A 1 205 ? 39.07600  22.33100  33.25400  1.000 16.66000 ? 206 LEU A C   1 
ATOM   1700 O O   . LEU A 1 205 ? 39.94700  23.17700  33.52300  1.000 14.03000 ? 206 LEU A O   1 
ATOM   1701 C CB  . LEU A 1 205 ? 38.72000  21.87900  30.82200  1.000 12.31000 ? 206 LEU A CB  1 
ATOM   1702 C CG  . LEU A 1 205 ? 37.75400  21.91100  29.60600  1.000 15.61000 ? 206 LEU A CG  1 
ATOM   1703 C CD1 . LEU A 1 205 ? 38.49700  21.63700  28.27700  1.000 17.85000 ? 206 LEU A CD1 1 
ATOM   1704 C CD2 . LEU A 1 205 ? 36.69400  20.85800  29.79700  1.000 12.77000 ? 206 LEU A CD2 1 
ATOM   1705 N N   . GLY A 1 206 ? 38.94200  21.16600  33.91200  1.000 15.00000 ? 207 GLY A N   1 
ATOM   1706 C CA  . GLY A 1 206 ? 39.90800  20.72100  34.90100  1.000 16.29000 ? 207 GLY A CA  1 
ATOM   1707 C C   . GLY A 1 206 ? 39.95300  21.57000  36.16400  1.000 20.65000 ? 207 GLY A C   1 
ATOM   1708 O O   . GLY A 1 206 ? 41.00700  21.62500  36.81100  1.000 19.00000 ? 207 GLY A O   1 
ATOM   1709 N N   . PHE A 1 207 ? 38.82600  22.20200  36.56700  1.000 15.16000 ? 208 PHE A N   1 
ATOM   1710 C CA  . PHE A 1 207 ? 38.86700  23.08400  37.73100  1.000 13.59000 ? 208 PHE A CA  1 
ATOM   1711 C C   . PHE A 1 207 ? 38.36800  22.39800  39.00000  1.000 16.99000 ? 208 PHE A C   1 
ATOM   1712 O O   . PHE A 1 207 ? 37.56800  21.46500  38.95500  1.000 14.12000 ? 208 PHE A O   1 
ATOM   1713 C CB  . PHE A 1 207 ? 38.05900  24.38100  37.46400  1.000 11.51000 ? 208 PHE A CB  1 
ATOM   1714 C CG  . PHE A 1 207 ? 36.61500  24.16000  37.01000  1.000 14.81000 ? 208 PHE A CG  1 
ATOM   1715 C CD1 . PHE A 1 207 ? 36.29100  24.01900  35.64400  1.000 13.32000 ? 208 PHE A CD1 1 
ATOM   1716 C CD2 . PHE A 1 207 ? 35.57700  24.22300  37.92700  1.000 17.74000 ? 208 PHE A CD2 1 
ATOM   1717 C CE1 . PHE A 1 207 ? 34.94400  23.85700  35.22700  1.000 15.57000 ? 208 PHE A CE1 1 
ATOM   1718 C CE2 . PHE A 1 207 ? 34.23400  24.02900  37.54300  1.000 16.78000 ? 208 PHE A CE2 1 
ATOM   1719 C CZ  . PHE A 1 207 ? 33.91000  23.85100  36.18100  1.000 16.36000 ? 208 PHE A CZ  1 
ATOM   1720 N N   . TYR A 1 208 ? 38.75400  22.98100  40.15000  1.000 13.52000 ? 209 TYR A N   1 
ATOM   1721 C CA  . TYR A 1 208 ? 38.29000  22.51700  41.45800  1.000 17.61000 ? 209 TYR A CA  1 
ATOM   1722 C C   . TYR A 1 208 ? 38.42100  23.71100  42.40900  1.000 15.91000 ? 209 TYR A C   1 
ATOM   1723 O O   . TYR A 1 208 ? 39.51000  24.30800  42.47900  1.000 14.30000 ? 209 TYR A O   1 
ATOM   1724 C CB  . TYR A 1 208 ? 39.09900  21.30800  41.99100  1.000 14.88000 ? 209 TYR A CB  1 
ATOM   1725 C CG  . TYR A 1 208 ? 38.62000  20.86000  43.34100  1.000 18.13000 ? 209 TYR A CG  1 
ATOM   1726 C CD1 . TYR A 1 208 ? 39.04200  21.53100  44.50900  1.000 16.04000 ? 209 TYR A CD1 1 
ATOM   1727 C CD2 . TYR A 1 208 ? 37.67100  19.81700  43.46000  1.000 17.11000 ? 209 TYR A CD2 1 
ATOM   1728 C CE1 . TYR A 1 208 ? 38.52500  21.18000  45.78400  1.000 16.46000 ? 209 TYR A CE1 1 
ATOM   1729 C CE2 . TYR A 1 208 ? 37.18900  19.44000  44.71700  1.000 14.97000 ? 209 TYR A CE2 1 
ATOM   1730 C CZ  . TYR A 1 208 ? 37.60200  20.12400  45.86900  1.000 18.06000 ? 209 TYR A CZ  1 
ATOM   1731 O OH  . TYR A 1 208 ? 37.06700  19.72600  47.09800  1.000 14.96000 ? 209 TYR A OH  1 
ATOM   1732 N N   . PRO A 1 209 ? 37.37300  24.03700  43.21000  1.000 14.72000 ? 210 PRO A N   1 
ATOM   1733 C CA  . PRO A 1 209 ? 36.11400  23.28300  43.41300  1.000 17.21000 ? 210 PRO A CA  1 
ATOM   1734 C C   . PRO A 1 209 ? 35.11300  23.50400  42.30300  1.000 16.09000 ? 210 PRO A C   1 
ATOM   1735 O O   . PRO A 1 209 ? 35.44500  24.18200  41.30800  1.000 16.58000 ? 210 PRO A O   1 
ATOM   1736 C CB  . PRO A 1 209 ? 35.62100  23.80600  44.80300  1.000 20.14000 ? 210 PRO A CB  1 
ATOM   1737 C CG  . PRO A 1 209 ? 36.15300  25.24900  44.83600  1.000 17.89000 ? 210 PRO A CG  1 
ATOM   1738 C CD  . PRO A 1 209 ? 37.51300  25.15500  44.16900  1.000 19.36000 ? 210 PRO A CD  1 
ATOM   1739 N N   . ALA A 1 210 ? 33.88300  22.96300  42.40800  1.000 13.87000 ? 211 ALA A N   1 
ATOM   1740 C CA  . ALA A 1 210 ? 32.98900  22.95300  41.27700  1.000 14.80000 ? 211 ALA A CA  1 
ATOM   1741 C C   . ALA A 1 210 ? 32.34900  24.31500  41.00700  1.000 14.96000 ? 211 ALA A C   1 
ATOM   1742 O O   . ALA A 1 210 ? 31.96500  24.59500  39.86600  1.000 17.43000 ? 211 ALA A O   1 
ATOM   1743 C CB  . ALA A 1 210 ? 31.87300  21.89700  41.48500  1.000 15.41000 ? 211 ALA A CB  1 
ATOM   1744 N N   . GLU A 1 211 ? 32.10000  25.09200  42.04600  1.000 18.89000 ? 212 GLU A N   1 
ATOM   1745 C CA  . GLU A 1 211 ? 31.51700  26.42100  41.88400  1.000 17.72000 ? 212 GLU A CA  1 
ATOM   1746 C C   . GLU A 1 211 ? 32.28100  27.24200  40.85000  1.000 17.91000 ? 212 GLU A C   1 
ATOM   1747 O O   . GLU A 1 211 ? 33.49400  27.39400  40.94500  1.000 16.67000 ? 212 GLU A O   1 
ATOM   1748 C CB  . GLU A 1 211 ? 31.55000  27.13000  43.23600  1.000 22.09000 ? 212 GLU A CB  1 
ATOM   1749 C CG  . GLU A 1 211 ? 31.36600  28.62500  43.15600  1.000 21.27000 ? 212 GLU A CG  1 
ATOM   1750 C CD  . GLU A 1 211 ? 29.98200  28.98800  42.63500  1.000 34.40000 ? 212 GLU A CD  1 
ATOM   1751 O OE1 . GLU A 1 211 ? 29.10100  28.09000  42.59800  1.000 33.73000 ? 212 GLU A OE1 1 
ATOM   1752 O OE2 . GLU A 1 211 ? 29.78800  30.17500  42.24400  1.000 39.87000 ? 212 GLU A OE2 1 
ATOM   1753 N N   . ILE A 1 212 ? 31.56400  27.79700  39.87700  1.000 18.31000 ? 213 ILE A N   1 
ATOM   1754 C CA  . ILE A 1 212 ? 32.18200  28.65000  38.85800  1.000 18.87000 ? 213 ILE A CA  1 
ATOM   1755 C C   . ILE A 1 212 ? 31.11800  29.56400  38.28500  1.000 16.16000 ? 213 ILE A C   1 
ATOM   1756 O O   . ILE A 1 212 ? 29.93600  29.24500  38.30600  1.000 17.95000 ? 213 ILE A O   1 
ATOM   1757 C CB  . ILE A 1 212 ? 32.80900  27.77000  37.75200  1.000 16.13000 ? 213 ILE A CB  1 
ATOM   1758 C CG1 . ILE A 1 212 ? 33.81900  28.51900  36.91900  1.000 19.03000 ? 213 ILE A CG1 1 
ATOM   1759 C CG2 . ILE A 1 212 ? 31.69300  27.13700  36.90800  1.000 12.51000 ? 213 ILE A CG2 1 
ATOM   1760 C CD1 . ILE A 1 212 ? 34.58200  27.55900  35.95700  1.000 18.69000 ? 213 ILE A CD1 1 
ATOM   1761 N N   . THR A 1 213 ? 31.54300  30.69400  37.71800  1.000 15.28000 ? 214 THR A N   1 
ATOM   1762 C CA  . THR A 1 213 ? 30.60200  31.49600  36.95000  1.000 16.74000 ? 214 THR A CA  1 
ATOM   1763 C C   . THR A 1 213 ? 31.16600  31.75100  35.56000  1.000 19.92000 ? 214 THR A C   1 
ATOM   1764 O O   . THR A 1 213 ? 32.31200  32.18100  35.43000  1.000 22.83000 ? 214 THR A O   1 
ATOM   1765 C CB  . THR A 1 213 ? 30.33400  32.81400  37.64600  1.000 22.28000 ? 214 THR A CB  1 
ATOM   1766 O OG1 . THR A 1 213 ? 29.81800  32.53200  38.95700  1.000 26.73000 ? 214 THR A OG1 1 
ATOM   1767 C CG2 . THR A 1 213 ? 29.30900  33.56000  36.85500  1.000 23.78000 ? 214 THR A CG2 1 
ATOM   1768 N N   . LEU A 1 214 ? 30.36300  31.47700  34.54200  1.000 16.63000 ? 215 LEU A N   1 
ATOM   1769 C CA  . LEU A 1 214 ? 30.77700  31.54500  33.14600  1.000 20.95000 ? 215 LEU A CA  1 
ATOM   1770 C C   . LEU A 1 214 ? 29.70900  32.32500  32.41600  1.000 17.93000 ? 215 LEU A C   1 
ATOM   1771 O O   . LEU A 1 214 ? 28.59200  31.84400  32.30600  1.000 22.69000 ? 215 LEU A O   1 
ATOM   1772 C CB  . LEU A 1 214 ? 30.84600  30.13900  32.52800  1.000 19.51000 ? 215 LEU A CB  1 
ATOM   1773 C CG  . LEU A 1 214 ? 32.08300  29.38800  32.16300  1.000 28.10000 ? 215 LEU A CG  1 
ATOM   1774 C CD1 . LEU A 1 214 ? 31.63600  28.22500  31.27100  1.000 15.80000 ? 215 LEU A CD1 1 
ATOM   1775 C CD2 . LEU A 1 214 ? 33.14800  30.36300  31.47000  1.000 18.15000 ? 215 LEU A CD2 1 
ATOM   1776 N N   . THR A 1 215 ? 30.04700  33.46900  31.83400  1.000 18.68000 ? 216 THR A N   1 
ATOM   1777 C CA  . THR A 1 215 ? 29.01400  34.23200  31.15500  1.000 21.03000 ? 216 THR A CA  1 
ATOM   1778 C C   . THR A 1 215 ? 29.57100  34.83600  29.86800  1.000 28.53000 ? 216 THR A C   1 
ATOM   1779 O O   . THR A 1 215 ? 30.78400  35.05700  29.74900  1.000 27.02000 ? 216 THR A O   1 
ATOM   1780 C CB  . THR A 1 215 ? 28.52700  35.34400  32.04500  1.000 17.75000 ? 216 THR A CB  1 
ATOM   1781 O OG1 . THR A 1 215 ? 29.64300  36.14700  32.35800  1.000 22.48000 ? 216 THR A OG1 1 
ATOM   1782 C CG2 . THR A 1 215 ? 27.94600  34.79200  33.34300  1.000 25.79000 ? 216 THR A CG2 1 
ATOM   1783 N N   . TRP A 1 216 ? 28.68800  35.10400  28.90700  1.000 24.52000 ? 217 TRP A N   1 
ATOM   1784 C CA  . TRP A 1 216 ? 29.08100  35.84700  27.71000  1.000 27.98000 ? 217 TRP A CA  1 
ATOM   1785 C C   . TRP A 1 216 ? 28.52600  37.25900  27.82600  1.000 26.05000 ? 217 TRP A C   1 
ATOM   1786 O O   . TRP A 1 216 ? 27.38600  37.43600  28.25600  1.000 28.29000 ? 217 TRP A O   1 
ATOM   1787 C CB  . TRP A 1 216 ? 28.49900  35.21600  26.45700  1.000 19.11000 ? 217 TRP A CB  1 
ATOM   1788 C CG  . TRP A 1 216 ? 29.32400  34.10200  25.94300  1.000 21.44000 ? 217 TRP A CG  1 
ATOM   1789 C CD1 . TRP A 1 216 ? 29.08200  32.76700  26.09200  1.000 21.50000 ? 217 TRP A CD1 1 
ATOM   1790 C CD2 . TRP A 1 216 ? 30.51200  34.21800  25.16900  1.000 16.68000 ? 217 TRP A CD2 1 
ATOM   1791 N NE1 . TRP A 1 216 ? 30.08000  32.03500  25.47900  1.000 23.53000 ? 217 TRP A NE1 1 
ATOM   1792 C CE2 . TRP A 1 216 ? 30.97100  32.90800  24.90900  1.000 19.00000 ? 217 TRP A CE2 1 
ATOM   1793 C CE3 . TRP A 1 216 ? 31.25000  35.31200  24.68900  1.000 17.42000 ? 217 TRP A CE3 1 
ATOM   1794 C CZ2 . TRP A 1 216 ? 32.11400  32.66100  24.14100  1.000 16.37000 ? 217 TRP A CZ2 1 
ATOM   1795 C CZ3 . TRP A 1 216 ? 32.40200  35.07800  23.95100  1.000 20.07000 ? 217 TRP A CZ3 1 
ATOM   1796 C CH2 . TRP A 1 216 ? 32.83000  33.77100  23.69600  1.000 19.28000 ? 217 TRP A CH2 1 
ATOM   1797 N N   . GLN A 1 217 ? 29.30400  38.24100  27.39500  1.000 22.13000 ? 218 GLN A N   1 
ATOM   1798 C CA  . GLN A 1 217 ? 28.84300  39.61900  27.25400  1.000 27.70000 ? 218 GLN A CA  1 
ATOM   1799 C C   . GLN A 1 217 ? 28.91700  40.04000  25.78900  1.000 37.03000 ? 218 GLN A C   1 
ATOM   1800 O O   . GLN A 1 217 ? 29.83600  39.61600  25.06600  1.000 29.30000 ? 218 GLN A O   1 
ATOM   1801 C CB  . GLN A 1 217 ? 29.71100  40.50600  28.09100  1.000 28.85000 ? 218 GLN A CB  1 
ATOM   1802 C CG  . GLN A 1 217 ? 29.32500  40.40700  29.54800  1.000 33.89000 ? 218 GLN A CG  1 
ATOM   1803 C CD  . GLN A 1 217 ? 30.19600  41.27100  30.41100  1.000 39.25000 ? 218 GLN A CD  1 
ATOM   1804 O OE1 . GLN A 1 217 ? 30.74200  42.26500  29.96400  1.000 38.61000 ? 218 GLN A OE1 1 
ATOM   1805 N NE2 . GLN A 1 217 ? 30.38700  40.85600  31.63700  1.000 36.54000 ? 218 GLN A NE2 1 
ATOM   1806 N N   . ARG A 1 218 ? 27.96000  40.86800  25.34800  1.000 28.23000 ? 219 ARG A N   1 
ATOM   1807 C CA  . ARG A 1 218 ? 28.06100  41.55200  24.05700  1.000 35.55000 ? 219 ARG A CA  1 
ATOM   1808 C C   . ARG A 1 218 ? 28.23000  43.04000  24.29100  1.000 34.56000 ? 219 ARG A C   1 
ATOM   1809 O O   . ARG A 1 218 ? 27.35100  43.67900  24.87900  1.000 35.09000 ? 219 ARG A O   1 
ATOM   1810 C CB  . ARG A 1 218 ? 26.84500  41.31500  23.17400  1.000 33.82000 ? 219 ARG A CB  1 
ATOM   1811 C CG  . ARG A 1 218 ? 26.90200  42.20200  21.94700  1.000 44.24000 ? 219 ARG A CG  1 
ATOM   1812 C CD  . ARG A 1 218 ? 26.49800  41.43700  20.71700  1.000 46.09000 ? 219 ARG A CD  1 
ATOM   1813 N NE  . ARG A 1 218 ? 25.06700  41.15600  20.62400  1.000 55.19000 ? 219 ARG A NE  1 
ATOM   1814 C CZ  . ARG A 1 218 ? 24.07300  42.03600  20.74300  1.000 59.62000 ? 219 ARG A CZ  1 
ATOM   1815 N NH1 . ARG A 1 218 ? 24.29600  43.31900  20.99200  1.000 56.54000 ? 219 ARG A NH1 1 
ATOM   1816 N NH2 . ARG A 1 218 ? 22.81600  41.62000  20.57700  1.000 51.30000 ? 219 ARG A NH2 1 
ATOM   1817 N N   . ASP A 1 219 ? 29.36900  43.57400  23.86300  1.000 34.36000 ? 220 ASP A N   1 
ATOM   1818 C CA  . ASP A 1 219 ? 29.74600  44.96200  24.11700  1.000 34.29000 ? 220 ASP A CA  1 
ATOM   1819 C C   . ASP A 1 219 ? 29.67400  45.30600  25.61100  1.000 44.03000 ? 220 ASP A C   1 
ATOM   1820 O O   . ASP A 1 219 ? 29.30500  46.41400  26.01900  1.000 32.30000 ? 220 ASP A O   1 
ATOM   1821 C CB  . ASP A 1 219 ? 28.88400  45.90900  23.28200  1.000 38.87000 ? 220 ASP A CB  1 
ATOM   1822 C CG  . ASP A 1 219 ? 29.17100  45.78100  21.80100  1.000 43.24000 ? 220 ASP A CG  1 
ATOM   1823 O OD1 . ASP A 1 219 ? 30.35700  45.62500  21.41800  1.000 45.39000 ? 220 ASP A OD1 1 
ATOM   1824 O OD2 . ASP A 1 219 ? 28.21700  45.86900  21.03200  1.000 42.14000 ? 220 ASP A OD2 1 
ATOM   1825 N N   . GLY A 1 220 ? 30.06700  44.36300  26.44400  1.000 27.98000 ? 221 GLY A N   1 
ATOM   1826 C CA  . GLY A 1 220 ? 29.97900  44.60000  27.86300  1.000 32.06000 ? 221 GLY A CA  1 
ATOM   1827 C C   . GLY A 1 220 ? 28.61500  44.41600  28.48400  1.000 34.57000 ? 221 GLY A C   1 
ATOM   1828 O O   . GLY A 1 220 ? 28.46000  44.69700  29.66800  1.000 41.30000 ? 221 GLY A O   1 
ATOM   1829 N N   . GLU A 1 221 ? 27.60400  43.96300  27.75400  1.000 35.92000 ? 222 GLU A N   1 
ATOM   1830 C CA  . GLU A 1 221 ? 26.31000  43.75300  28.38500  1.000 33.02000 ? 222 GLU A CA  1 
ATOM   1831 C C   . GLU A 1 221 ? 25.93400  42.26700  28.40200  1.000 44.23000 ? 222 GLU A C   1 
ATOM   1832 O O   . GLU A 1 221 ? 26.25900  41.50700  27.48900  1.000 33.05000 ? 222 GLU A O   1 
ATOM   1833 C CB  . GLU A 1 221 ? 25.23300  44.60800  27.72000  1.000 38.48000 ? 222 GLU A CB  1 
ATOM   1834 C CG  . GLU A 1 221 ? 24.32600  45.25300  28.76900  0.000 38.64000 ? 222 GLU A CG  1 
ATOM   1835 C CD  . GLU A 1 221 ? 25.06600  46.24000  29.66800  0.000 38.90000 ? 222 GLU A CD  1 
ATOM   1836 O OE1 . GLU A 1 221 ? 25.59500  47.24700  29.15500  0.000 38.83000 ? 222 GLU A OE1 1 
ATOM   1837 O OE2 . GLU A 1 221 ? 25.11600  46.00200  30.89500  0.000 39.09000 ? 222 GLU A OE2 1 
ATOM   1838 N N   . ASP A 1 222 ? 25.23900  41.84600  29.45000  1.000 36.13000 ? 223 ASP A N   1 
ATOM   1839 C CA  . ASP A 1 222 ? 25.00700  40.42100  29.64100  1.000 41.36000 ? 223 ASP A CA  1 
ATOM   1840 C C   . ASP A 1 222 ? 24.08000  39.80900  28.59000  1.000 44.39000 ? 223 ASP A C   1 
ATOM   1841 O O   . ASP A 1 222 ? 23.14300  40.43300  28.08300  1.000 47.82000 ? 223 ASP A O   1 
ATOM   1842 C CB  . ASP A 1 222 ? 24.50300  40.14300  31.06500  1.000 55.52000 ? 223 ASP A CB  1 
ATOM   1843 C CG  . ASP A 1 222 ? 25.66000  40.07800  32.10600  1.000 54.54000 ? 223 ASP A CG  1 
ATOM   1844 O OD1 . ASP A 1 222 ? 26.31700  39.00500  32.19600  1.000 47.51000 ? 223 ASP A OD1 1 
ATOM   1845 O OD2 . ASP A 1 222 ? 25.94800  41.08100  32.79700  1.000 59.11000 ? 223 ASP A OD2 1 
ATOM   1846 N N   . GLN A 1 223 ? 24.38600  38.56600  28.24000  1.000 31.57000 ? 224 GLN A N   1 
ATOM   1847 C CA  . GLN A 1 223 ? 23.68100  37.85800  27.19300  1.000 35.01000 ? 224 GLN A CA  1 
ATOM   1848 C C   . GLN A 1 223 ? 22.92900  36.67700  27.76600  1.000 39.06000 ? 224 GLN A C   1 
ATOM   1849 O O   . GLN A 1 223 ? 22.82600  35.63200  27.13800  1.000 30.69000 ? 224 GLN A O   1 
ATOM   1850 C CB  . GLN A 1 223 ? 24.64500  37.39800  26.10900  1.000 34.21000 ? 224 GLN A CB  1 
ATOM   1851 C CG  . GLN A 1 223 ? 25.31200  38.55400  25.41400  1.000 33.26000 ? 224 GLN A CG  1 
ATOM   1852 C CD  . GLN A 1 223 ? 24.32800  39.25700  24.50800  1.000 43.25000 ? 224 GLN A CD  1 
ATOM   1853 O OE1 . GLN A 1 223 ? 23.91200  40.36000  24.81400  1.000 45.63000 ? 224 GLN A OE1 1 
ATOM   1854 N NE2 . GLN A 1 223 ? 23.94300  38.62000  23.40000  1.000 42.25000 ? 224 GLN A NE2 1 
ATOM   1855 N N   . THR A 1 224 ? 22.33500  36.85200  28.95100  1.000 42.10000 ? 225 THR A N   1 
ATOM   1856 C CA  . THR A 1 224 ? 21.83000  35.70700  29.70500  1.000 38.99000 ? 225 THR A CA  1 
ATOM   1857 C C   . THR A 1 224 ? 20.84700  34.87400  28.88500  1.000 40.89000 ? 225 THR A C   1 
ATOM   1858 O O   . THR A 1 224 ? 21.00400  33.64600  28.76800  1.000 27.73000 ? 225 THR A O   1 
ATOM   1859 C CB  . THR A 1 224 ? 21.17500  36.18400  31.00800  1.000 52.89000 ? 225 THR A CB  1 
ATOM   1860 O OG1 . THR A 1 224 ? 22.18500  36.60300  31.94500  1.000 51.12000 ? 225 THR A OG1 1 
ATOM   1861 C CG2 . THR A 1 224 ? 20.38100  35.04200  31.64000  1.000 55.41000 ? 225 THR A CG2 1 
ATOM   1862 N N   . GLN A 1 225 ? 19.82700  35.52700  28.29300  1.000 41.55000 ? 226 GLN A N   1 
ATOM   1863 C CA  . GLN A 1 225 ? 18.78000  34.79400  27.57300  1.000 44.69000 ? 226 GLN A CA  1 
ATOM   1864 C C   . GLN A 1 225 ? 19.24200  34.24200  26.23000  1.000 37.39000 ? 226 GLN A C   1 
ATOM   1865 O O   . GLN A 1 225 ? 18.52100  33.42300  25.65300  1.000 37.31000 ? 226 GLN A O   1 
ATOM   1866 C CB  . GLN A 1 225 ? 17.54100  35.67100  27.36200  1.000 44.50000 ? 226 GLN A CB  1 
ATOM   1867 C CG  . GLN A 1 225 ? 16.58400  35.69200  28.54500  0.000 51.39000 ? 226 GLN A CG  1 
ATOM   1868 C CD  . GLN A 1 225 ? 15.93500  37.04300  28.75500  0.000 58.23000 ? 226 GLN A CD  1 
ATOM   1869 O OE1 . GLN A 1 225 ? 15.01400  37.18300  29.56000  0.000 59.84000 ? 226 GLN A OE1 1 
ATOM   1870 N NE2 . GLN A 1 225 ? 16.40600  38.04600  28.02500  0.000 60.96000 ? 226 GLN A NE2 1 
ATOM   1871 N N   . ASP A 1 226 ? 20.42300  34.64200  25.74000  1.000 32.14000 ? 227 ASP A N   1 
ATOM   1872 C CA  . ASP A 1 226 ? 20.99800  34.15700  24.48900  1.000 31.69000 ? 227 ASP A CA  1 
ATOM   1873 C C   . ASP A 1 226 ? 22.17300  33.18800  24.68400  1.000 29.44000 ? 227 ASP A C   1 
ATOM   1874 O O   . ASP A 1 226 ? 22.79600  32.78000  23.69800  1.000 28.43000 ? 227 ASP A O   1 
ATOM   1875 C CB  . ASP A 1 226 ? 21.44900  35.34300  23.65800  1.000 30.54000 ? 227 ASP A CB  1 
ATOM   1876 C CG  . ASP A 1 226 ? 20.28200  36.18000  23.15700  1.000 45.71000 ? 227 ASP A CG  1 
ATOM   1877 O OD1 . ASP A 1 226 ? 19.29800  35.57800  22.69100  1.000 37.64000 ? 227 ASP A OD1 1 
ATOM   1878 O OD2 . ASP A 1 226 ? 20.33200  37.42700  23.28400  1.000 45.18000 ? 227 ASP A OD2 1 
ATOM   1879 N N   . THR A 1 227 ? 22.46500  32.79000  25.91400  1.000 30.18000 ? 228 THR A N   1 
ATOM   1880 C CA  . THR A 1 227 ? 23.57600  31.90000  26.22700  1.000 27.02000 ? 228 THR A CA  1 
ATOM   1881 C C   . THR A 1 227 ? 23.05000  30.52100  26.56800  1.000 29.58000 ? 228 THR A C   1 
ATOM   1882 O O   . THR A 1 227 ? 22.26400  30.37600  27.51500  1.000 32.66000 ? 228 THR A O   1 
ATOM   1883 C CB  . THR A 1 227 ? 24.38400  32.44400  27.41300  1.000 24.19000 ? 228 THR A CB  1 
ATOM   1884 O OG1 . THR A 1 227 ? 24.90700  33.72700  27.09200  1.000 24.77000 ? 228 THR A OG1 1 
ATOM   1885 C CG2 . THR A 1 227 ? 25.56200  31.53000  27.78500  1.000 21.30000 ? 228 THR A CG2 1 
ATOM   1886 N N   . GLU A 1 228 ? 23.53600  29.50800  25.85300  1.000 19.88000 ? 229 GLU A N   1 
ATOM   1887 C CA  . GLU A 1 228 ? 23.33900  28.11100  26.23400  1.000 20.70000 ? 229 GLU A CA  1 
ATOM   1888 C C   . GLU A 1 228 ? 24.43300  27.71600  27.23900  1.000 27.82000 ? 229 GLU A C   1 
ATOM   1889 O O   . GLU A 1 228 ? 25.63400  27.82100  26.94000  1.000 24.13000 ? 229 GLU A O   1 
ATOM   1890 C CB  . GLU A 1 228 ? 23.41400  27.22800  25.00700  1.000 24.18000 ? 229 GLU A CB  1 
ATOM   1891 C CG  . GLU A 1 228 ? 23.38400  25.76500  25.36200  1.000 28.47000 ? 229 GLU A CG  1 
ATOM   1892 C CD  . GLU A 1 228 ? 23.52400  24.86500  24.15000  1.000 34.66000 ? 229 GLU A CD  1 
ATOM   1893 O OE1 . GLU A 1 228 ? 24.16200  25.26700  23.12000  1.000 39.76000 ? 229 GLU A OE1 1 
ATOM   1894 O OE2 . GLU A 1 228 ? 23.01200  23.73500  24.24200  1.000 43.59000 ? 229 GLU A OE2 1 
ATOM   1895 N N   . LEU A 1 229 ? 24.04200  27.30300  28.44500  1.000 18.09000 ? 230 LEU A N   1 
ATOM   1896 C CA  . LEU A 1 229 ? 24.97400  27.08500  29.55800  1.000 22.66000 ? 230 LEU A CA  1 
ATOM   1897 C C   . LEU A 1 229 ? 24.73200  25.67800  30.09200  1.000 33.59000 ? 230 LEU A C   1 
ATOM   1898 O O   . LEU A 1 229 ? 23.65500  25.42700  30.65500  1.000 26.95000 ? 230 LEU A O   1 
ATOM   1899 C CB  . LEU A 1 229 ? 24.73700  28.13800  30.64200  1.000 23.92000 ? 230 LEU A CB  1 
ATOM   1900 C CG  . LEU A 1 229 ? 25.58400  28.27300  31.89500  1.000 34.38000 ? 230 LEU A CG  1 
ATOM   1901 C CD1 . LEU A 1 229 ? 26.96300  28.76600  31.52600  1.000 20.27000 ? 230 LEU A CD1 1 
ATOM   1902 C CD2 . LEU A 1 229 ? 24.92000  29.27100  32.83500  1.000 28.71000 ? 230 LEU A CD2 1 
ATOM   1903 N N   . VAL A 1 230 ? 25.70700  24.73500  29.89600  1.000 22.09000 ? 231 VAL A N   1 
ATOM   1904 C CA  . VAL A 1 230 ? 25.48600  23.36800  30.40800  1.000 17.58000 ? 231 VAL A CA  1 
ATOM   1905 C C   . VAL A 1 230 ? 25.73000  23.32200  31.90600  1.000 19.46000 ? 231 VAL A C   1 
ATOM   1906 O O   . VAL A 1 230 ? 26.47500  24.13600  32.43600  1.000 14.95000 ? 231 VAL A O   1 
ATOM   1907 C CB  . VAL A 1 230 ? 26.32500  22.30300  29.67700  1.000 16.39000 ? 231 VAL A CB  1 
ATOM   1908 C CG1 . VAL A 1 230 ? 26.01900  22.28300  28.19600  1.000 17.88000 ? 231 VAL A CG1 1 
ATOM   1909 C CG2 . VAL A 1 230 ? 27.84000  22.51900  29.90800  1.000 16.06000 ? 231 VAL A CG2 1 
ATOM   1910 N N   . GLU A 1 231 ? 25.14200  22.32100  32.58700  1.000 12.27000 ? 232 GLU A N   1 
ATOM   1911 C CA  . GLU A 1 231 ? 25.39900  22.21400  34.00400  1.000 12.75000 ? 232 GLU A CA  1 
ATOM   1912 C C   . GLU A 1 231 ? 26.81100  21.71300  34.22500  1.000 12.12000 ? 232 GLU A C   1 
ATOM   1913 O O   . GLU A 1 231 ? 27.38200  21.00400  33.39000  1.000 14.33000 ? 232 GLU A O   1 
ATOM   1914 C CB  . GLU A 1 231 ? 24.41500  21.28100  34.69400  1.000 14.26000 ? 232 GLU A CB  1 
ATOM   1915 C CG  . GLU A 1 231 ? 24.14400  20.20600  34.00600  1.000 30.16000 ? 232 GLU A CG  1 
ATOM   1916 C CD  . GLU A 1 231 ? 23.54000  19.09100  34.89000  1.000 55.44000 ? 232 GLU A CD  1 
ATOM   1917 O OE1 . GLU A 1 231 ? 23.29300  19.16500  36.09900  1.000 33.83000 ? 232 GLU A OE1 1 
ATOM   1918 O OE2 . GLU A 1 231 ? 23.20900  17.96200  34.42300  1.000 47.81000 ? 232 GLU A OE2 1 
ATOM   1919 N N   . THR A 1 232 ? 27.37700  22.15900  35.33200  1.000 12.08000 ? 233 THR A N   1 
ATOM   1920 C CA  . THR A 1 232 ? 28.73400  21.78800  35.69300  1.000 16.85000 ? 233 THR A CA  1 
ATOM   1921 C C   . THR A 1 232 ? 28.78100  20.28200  35.84000  1.000 16.60000 ? 233 THR A C   1 
ATOM   1922 O O   . THR A 1 232 ? 27.88400  19.71000  36.44100  1.000 13.57000 ? 233 THR A O   1 
ATOM   1923 C CB  . THR A 1 232 ? 29.12100  22.48600  37.00100  1.000 13.77000 ? 233 THR A CB  1 
ATOM   1924 O OG1 . THR A 1 232 ? 29.11100  23.91100  36.81400  1.000 15.57000 ? 233 THR A OG1 1 
ATOM   1925 C CG2 . THR A 1 232 ? 30.52900  22.02000  37.48800  1.000 14.25000 ? 233 THR A CG2 1 
ATOM   1926 N N   . ARG A 1 233 ? 29.80500  19.63000  35.26400  1.000 12.92000 ? 234 ARG A N   1 
ATOM   1927 C CA  . ARG A 1 233 ? 29.80900  18.17400  35.23300  1.000 11.73000 ? 234 ARG A CA  1 
ATOM   1928 C C   . ARG A 1 233 ? 31.15400  17.62700  35.68300  1.000 11.87000 ? 234 ARG A C   1 
ATOM   1929 O O   . ARG A 1 233 ? 32.18400  18.27600  35.51700  1.000 10.30000 ? 234 ARG A O   1 
ATOM   1930 C CB  . ARG A 1 233 ? 29.48800  17.63800  33.82600  1.000 9.64000  ? 234 ARG A CB  1 
ATOM   1931 C CG  . ARG A 1 233 ? 30.58000  18.06500  32.80800  1.000 11.87000 ? 234 ARG A CG  1 
ATOM   1932 C CD  . ARG A 1 233 ? 30.06100  18.05900  31.35300  1.000 16.55000 ? 234 ARG A CD  1 
ATOM   1933 N NE  . ARG A 1 233 ? 31.14800  18.17200  30.36100  1.000 13.16000 ? 234 ARG A NE  1 
ATOM   1934 C CZ  . ARG A 1 233 ? 30.92100  18.30600  29.05800  1.000 15.51000 ? 234 ARG A CZ  1 
ATOM   1935 N NH1 . ARG A 1 233 ? 29.68900  18.46400  28.58400  1.000 13.21000 ? 234 ARG A NH1 1 
ATOM   1936 N NH2 . ARG A 1 233 ? 31.95000  18.24600  28.21500  1.000 15.64000 ? 234 ARG A NH2 1 
ATOM   1937 N N   . PRO A 1 234 ? 31.17900  16.44200  36.27600  1.000 11.75000 ? 235 PRO A N   1 
ATOM   1938 C CA  . PRO A 1 234 ? 32.48300  15.90600  36.72500  1.000 10.49000 ? 235 PRO A CA  1 
ATOM   1939 C C   . PRO A 1 234 ? 33.26800  15.34600  35.56000  1.000 11.54000 ? 235 PRO A C   1 
ATOM   1940 O O   . PRO A 1 234 ? 32.73200  14.56800  34.76400  1.000 13.50000 ? 235 PRO A O   1 
ATOM   1941 C CB  . PRO A 1 234 ? 32.09100  14.78300  37.70600  1.000 15.34000 ? 235 PRO A CB  1 
ATOM   1942 C CG  . PRO A 1 234 ? 30.69100  14.34300  37.18900  1.000 15.89000 ? 235 PRO A CG  1 
ATOM   1943 C CD  . PRO A 1 234 ? 30.04100  15.62600  36.73700  1.000 14.97000 ? 235 PRO A CD  1 
ATOM   1944 N N   . ALA A 1 235 ? 34.57500  15.67300  35.51900  1.000 12.90000 ? 236 ALA A N   1 
ATOM   1945 C CA  . ALA A 1 235 ? 35.47700  15.03900  34.52800  1.000 11.33000 ? 236 ALA A CA  1 
ATOM   1946 C C   . ALA A 1 235 ? 35.67300  13.56900  34.86000  1.000 14.22000 ? 236 ALA A C   1 
ATOM   1947 O O   . ALA A 1 235 ? 35.91300  12.75300  33.97200  1.000 15.24000 ? 236 ALA A O   1 
ATOM   1948 C CB  . ALA A 1 235 ? 36.84800  15.76300  34.50100  1.000 11.45000 ? 236 ALA A CB  1 
ATOM   1949 N N   . GLY A 1 236 ? 35.55100  13.21200  36.15300  1.000 13.66000 ? 237 GLY A N   1 
ATOM   1950 C CA  . GLY A 1 236 ? 35.79000  11.85300  36.62300  1.000 14.69000 ? 237 GLY A CA  1 
ATOM   1951 C C   . GLY A 1 236 ? 37.15700  11.62200  37.24800  1.000 19.46000 ? 237 GLY A C   1 
ATOM   1952 O O   . GLY A 1 236 ? 37.43800  10.49500  37.67400  1.000 19.02000 ? 237 GLY A O   1 
ATOM   1953 N N   . ASP A 1 237 ? 38.01700  12.64600  37.29100  1.000 14.47000 ? 238 ASP A N   1 
ATOM   1954 C CA  . ASP A 1 237 ? 39.30500  12.60400  37.96700  1.000 15.40000 ? 238 ASP A CA  1 
ATOM   1955 C C   . ASP A 1 237 ? 39.30500  13.51600  39.18900  1.000 18.04000 ? 238 ASP A C   1 
ATOM   1956 O O   . ASP A 1 237 ? 40.35500  13.91600  39.67200  1.000 18.82000 ? 238 ASP A O   1 
ATOM   1957 C CB  . ASP A 1 237 ? 40.39500  13.02200  37.00300  1.000 19.49000 ? 238 ASP A CB  1 
ATOM   1958 C CG  . ASP A 1 237 ? 40.13200  14.40500  36.37900  1.000 22.56000 ? 238 ASP A CG  1 
ATOM   1959 O OD1 . ASP A 1 237 ? 39.18200  15.11600  36.80800  1.000 13.67000 ? 238 ASP A OD1 1 
ATOM   1960 O OD2 . ASP A 1 237 ? 40.87800  14.76400  35.43800  1.000 21.98000 ? 238 ASP A OD2 1 
ATOM   1961 N N   . GLY A 1 238 ? 38.14900  13.93300  39.62800  1.000 14.51000 ? 239 GLY A N   1 
ATOM   1962 C CA  . GLY A 1 238 ? 38.05400  14.84000  40.73600  1.000 22.28000 ? 239 GLY A CA  1 
ATOM   1963 C C   . GLY A 1 238 ? 37.88600  16.29200  40.34600  1.000 20.99000 ? 239 GLY A C   1 
ATOM   1964 O O   . GLY A 1 238 ? 37.56600  17.10000  41.22700  1.000 19.45000 ? 239 GLY A O   1 
ATOM   1965 N N   . THR A 1 239 ? 38.03800  16.64300  39.05300  1.000 14.93000 ? 240 THR A N   1 
ATOM   1966 C CA  . THR A 1 239 ? 37.84800  18.01000  38.61800  1.000 12.12000 ? 240 THR A CA  1 
ATOM   1967 C C   . THR A 1 239 ? 36.56700  18.09500  37.80400  1.000 13.25000 ? 240 THR A C   1 
ATOM   1968 O O   . THR A 1 239 ? 35.85900  17.08400  37.59500  1.000 16.19000 ? 240 THR A O   1 
ATOM   1969 C CB  . THR A 1 239 ? 39.02800  18.52900  37.80500  1.000 13.41000 ? 240 THR A CB  1 
ATOM   1970 O OG1 . THR A 1 239 ? 39.10400  17.80100  36.58600  1.000 18.98000 ? 240 THR A OG1 1 
ATOM   1971 C CG2 . THR A 1 239 ? 40.37700  18.41400  38.63000  1.000 17.12000 ? 240 THR A CG2 1 
ATOM   1972 N N   . PHE A 1 240 ? 36.21800  19.33100  37.41500  1.000 13.97000 ? 241 PHE A N   1 
ATOM   1973 C CA  . PHE A 1 240 ? 34.93900  19.60600  36.76400  1.000 15.20000 ? 241 PHE A CA  1 
ATOM   1974 C C   . PHE A 1 240 ? 35.09400  20.34000  35.43200  1.000 12.79000 ? 241 PHE A C   1 
ATOM   1975 O O   . PHE A 1 240 ? 36.14600  20.90000  35.11700  1.000 15.86000 ? 241 PHE A O   1 
ATOM   1976 C CB  . PHE A 1 240 ? 34.03500  20.43100  37.72500  1.000 14.85000 ? 241 PHE A CB  1 
ATOM   1977 C CG  . PHE A 1 240 ? 33.74800  19.68200  39.00000  1.000 14.51000 ? 241 PHE A CG  1 
ATOM   1978 C CD1 . PHE A 1 240 ? 34.63500  19.72900  40.06500  1.000 15.56000 ? 241 PHE A CD1 1 
ATOM   1979 C CD2 . PHE A 1 240 ? 32.60200  18.87700  39.11400  1.000 14.58000 ? 241 PHE A CD2 1 
ATOM   1980 C CE1 . PHE A 1 240 ? 34.37300  18.97500  41.22800  1.000 13.36000 ? 241 PHE A CE1 1 
ATOM   1981 C CE2 . PHE A 1 240 ? 32.36500  18.14700  40.27000  1.000 16.77000 ? 241 PHE A CE2 1 
ATOM   1982 C CZ  . PHE A 1 240 ? 33.25900  18.19500  41.31400  1.000 15.55000 ? 241 PHE A CZ  1 
ATOM   1983 N N   . GLN A 1 241 ? 34.00800  20.33300  34.64800  1.000 11.15000 ? 242 GLN A N   1 
ATOM   1984 C CA  . GLN A 1 241 ? 33.95600  20.98900  33.33600  1.000 10.38000 ? 242 GLN A CA  1 
ATOM   1985 C C   . GLN A 1 241 ? 32.66500  21.79600  33.19800  1.000 12.77000 ? 242 GLN A C   1 
ATOM   1986 O O   . GLN A 1 241 ? 31.64600  21.47500  33.80200  1.000 13.02000 ? 242 GLN A O   1 
ATOM   1987 C CB  . GLN A 1 241 ? 33.95500  19.93400  32.19700  1.000 10.71000 ? 242 GLN A CB  1 
ATOM   1988 C CG  . GLN A 1 241 ? 35.09800  18.82100  32.37700  1.000 13.89000 ? 242 GLN A CG  1 
ATOM   1989 C CD  . GLN A 1 241 ? 34.96600  17.75700  31.30000  1.000 14.93000 ? 242 GLN A CD  1 
ATOM   1990 O OE1 . GLN A 1 241 ? 33.93200  17.69000  30.67400  1.000 15.08000 ? 242 GLN A OE1 1 
ATOM   1991 N NE2 . GLN A 1 241 ? 36.03100  16.93500  31.06400  1.000 12.64000 ? 242 GLN A NE2 1 
ATOM   1992 N N   . LYS A 1 242 ? 32.68300  22.79100  32.32500  1.000 12.71000 ? 243 LYS A N   1 
ATOM   1993 C CA  . LYS A 1 242 ? 31.47100  23.55000  32.03000  1.000 11.44000 ? 243 LYS A CA  1 
ATOM   1994 C C   . LYS A 1 242 ? 31.74800  24.30000  30.75800  1.000 13.25000 ? 243 LYS A C   1 
ATOM   1995 O O   . LYS A 1 242 ? 32.90200  24.60400  30.45200  1.000 15.42000 ? 243 LYS A O   1 
ATOM   1996 C CB  . LYS A 1 242 ? 31.15000  24.53100  33.16100  1.000 14.56000 ? 243 LYS A CB  1 
ATOM   1997 C CG  . LYS A 1 242 ? 29.71800  25.11700  33.12400  1.000 15.97000 ? 243 LYS A CG  1 
ATOM   1998 C CD  . LYS A 1 242 ? 29.54900  26.15200  34.23300  1.000 16.31000 ? 243 LYS A CD  1 
ATOM   1999 C CE  . LYS A 1 242 ? 28.00700  26.57600  34.40000  1.000 16.77000 ? 243 LYS A CE  1 
ATOM   2000 N NZ  . LYS A 1 242 ? 27.20600  25.44900  34.84400  1.000 12.74000 ? 243 LYS A NZ  1 
ATOM   2001 N N   . TRP A 1 243 ? 30.70700  24.58200  29.99900  1.000 13.30000 ? 244 TRP A N   1 
ATOM   2002 C CA  . TRP A 1 243 ? 30.88400  25.51400  28.90000  1.000 16.30000 ? 244 TRP A CA  1 
ATOM   2003 C C   . TRP A 1 243 ? 29.62200  26.36300  28.74200  1.000 17.00000 ? 244 TRP A C   1 
ATOM   2004 O O   . TRP A 1 243 ? 28.55700  26.01900  29.26800  1.000 13.99000 ? 244 TRP A O   1 
ATOM   2005 C CB  . TRP A 1 243 ? 31.22900  24.81800  27.56000  1.000 12.31000 ? 244 TRP A CB  1 
ATOM   2006 C CG  . TRP A 1 243 ? 30.26900  23.73500  27.01100  1.000 16.38000 ? 244 TRP A CG  1 
ATOM   2007 C CD1 . TRP A 1 243 ? 30.51200  22.36600  27.00700  1.000 17.87000 ? 244 TRP A CD1 1 
ATOM   2008 C CD2 . TRP A 1 243 ? 29.01600  23.90400  26.31400  1.000 13.57000 ? 244 TRP A CD2 1 
ATOM   2009 N NE1 . TRP A 1 243 ? 29.51100  21.70000  26.34200  1.000 16.25000 ? 244 TRP A NE1 1 
ATOM   2010 C CE2 . TRP A 1 243 ? 28.56700  22.60700  25.93700  1.000 19.04000 ? 244 TRP A CE2 1 
ATOM   2011 C CE3 . TRP A 1 243 ? 28.21400  25.02300  25.98400  1.000 15.97000 ? 244 TRP A CE3 1 
ATOM   2012 C CZ2 . TRP A 1 243 ? 27.36400  22.39700  25.22000  1.000 20.99000 ? 244 TRP A CZ2 1 
ATOM   2013 C CZ3 . TRP A 1 243 ? 27.00100  24.80700  25.29700  1.000 19.43000 ? 244 TRP A CZ3 1 
ATOM   2014 C CH2 . TRP A 1 243 ? 26.59500  23.51400  24.92300  1.000 20.79000 ? 244 TRP A CH2 1 
ATOM   2015 N N   . ALA A 1 244 ? 29.79300  27.50200  28.04600  1.000 15.42000 ? 245 ALA A N   1 
ATOM   2016 C CA  . ALA A 1 244 ? 28.74300  28.49000  27.76700  1.000 16.02000 ? 245 ALA A CA  1 
ATOM   2017 C C   . ALA A 1 244 ? 28.87200  28.86800  26.29700  1.000 19.42000 ? 245 ALA A C   1 
ATOM   2018 O O   . ALA A 1 244 ? 29.98300  29.08500  25.80200  1.000 18.90000 ? 245 ALA A O   1 
ATOM   2019 C CB  . ALA A 1 244 ? 28.89800  29.71700  28.64300  1.000 17.04000 ? 245 ALA A CB  1 
ATOM   2020 N N   . ALA A 1 245 ? 27.76200  28.94700  25.58600  1.000 17.07000 ? 246 ALA A N   1 
ATOM   2021 C CA  . ALA A 1 245 ? 27.83800  29.21600  24.15200  1.000 19.18000 ? 246 ALA A CA  1 
ATOM   2022 C C   . ALA A 1 245 ? 26.81200  30.25800  23.72400  1.000 28.26000 ? 246 ALA A C   1 
ATOM   2023 O O   . ALA A 1 245 ? 25.70300  30.29400  24.26100  1.000 22.18000 ? 246 ALA A O   1 
ATOM   2024 C CB  . ALA A 1 245 ? 27.57300  27.92000  23.35100  1.000 15.79000 ? 246 ALA A CB  1 
ATOM   2025 N N   . VAL A 1 246 ? 27.17800  31.06400  22.71400  1.000 23.55000 ? 247 VAL A N   1 
ATOM   2026 C CA  . VAL A 1 246 ? 26.32200  32.05900  22.10000  1.000 20.52000 ? 247 VAL A CA  1 
ATOM   2027 C C   . VAL A 1 246 ? 26.45400  31.93300  20.59400  1.000 30.31000 ? 247 VAL A C   1 
ATOM   2028 O O   . VAL A 1 246 ? 27.50800  31.55400  20.07000  1.000 27.40000 ? 247 VAL A O   1 
ATOM   2029 C CB  . VAL A 1 246 ? 26.65900  33.51600  22.53300  1.000 20.59000 ? 247 VAL A CB  1 
ATOM   2030 C CG1 . VAL A 1 246 ? 26.36300  33.76500  23.96200  1.000 32.10000 ? 247 VAL A CG1 1 
ATOM   2031 C CG2 . VAL A 1 246 ? 28.12200  33.87800  22.27700  1.000 23.47000 ? 247 VAL A CG2 1 
ATOM   2032 N N   . VAL A 1 247 ? 25.38200  32.25800  19.89500  1.000 27.42000 ? 248 VAL A N   1 
ATOM   2033 C CA  . VAL A 1 247 ? 25.36600  32.26800  18.43200  1.000 27.65000 ? 248 VAL A CA  1 
ATOM   2034 C C   . VAL A 1 247 ? 25.53900  33.71200  17.98600  1.000 34.90000 ? 248 VAL A C   1 
ATOM   2035 O O   . VAL A 1 247 ? 24.77500  34.58900  18.40000  1.000 29.23000 ? 248 VAL A O   1 
ATOM   2036 C CB  . VAL A 1 247 ? 24.07600  31.65200  17.88500  1.000 27.26000 ? 248 VAL A CB  1 
ATOM   2037 C CG1 . VAL A 1 247 ? 24.05600  31.80800  16.40100  1.000 33.04000 ? 248 VAL A CG1 1 
ATOM   2038 C CG2 . VAL A 1 247 ? 23.99900  30.17400  18.24400  1.000 23.46000 ? 248 VAL A CG2 1 
ATOM   2039 N N   . VAL A 1 248 ? 26.58700  33.98800  17.21100  1.000 28.73000 ? 249 VAL A N   1 
ATOM   2040 C CA  . VAL A 1 248 ? 26.91600  35.37500  16.87800  1.000 34.80000 ? 249 VAL A CA  1 
ATOM   2041 C C   . VAL A 1 248 ? 26.95200  35.56000  15.36200  1.000 33.69000 ? 249 VAL A C   1 
ATOM   2042 O O   . VAL A 1 248 ? 27.26700  34.61600  14.61900  1.000 29.16000 ? 249 VAL A O   1 
ATOM   2043 C CB  . VAL A 1 248 ? 28.25400  35.82800  17.49100  1.000 32.21000 ? 249 VAL A CB  1 
ATOM   2044 C CG1 . VAL A 1 248 ? 28.39000  35.38500  18.96100  1.000 32.21000 ? 249 VAL A CG1 1 
ATOM   2045 C CG2 . VAL A 1 248 ? 29.35100  35.26300  16.73600  1.000 27.58000 ? 249 VAL A CG2 1 
ATOM   2046 N N   . PRO A 1 249 ? 26.63100  36.75200  14.87700  1.000 32.29000 ? 250 PRO A N   1 
ATOM   2047 C CA  . PRO A 1 249 ? 26.77900  37.05200  13.44100  1.000 37.04000 ? 250 PRO A CA  1 
ATOM   2048 C C   . PRO A 1 249 ? 28.23500  37.09400  12.98800  1.000 34.17000 ? 250 PRO A C   1 
ATOM   2049 O O   . PRO A 1 249 ? 29.08700  37.73200  13.62900  1.000 38.62000 ? 250 PRO A O   1 
ATOM   2050 C CB  . PRO A 1 249 ? 26.14100  38.44200  13.31000  1.000 36.69000 ? 250 PRO A CB  1 
ATOM   2051 C CG  . PRO A 1 249 ? 25.30200  38.61800  14.59600  1.000 40.56000 ? 250 PRO A CG  1 
ATOM   2052 C CD  . PRO A 1 249 ? 26.06300  37.87900  15.63400  1.000 33.99000 ? 250 PRO A CD  1 
ATOM   2053 N N   . SER A 1 250 ? 28.51300  36.45400  11.83800  1.000 34.45000 ? 251 SER A N   1 
ATOM   2054 C CA  . SER A 1 250 ? 29.87300  36.48700  11.28100  1.000 33.79000 ? 251 SER A CA  1 
ATOM   2055 C C   . SER A 1 250 ? 30.41000  37.90400  11.22400  1.000 33.80000 ? 251 SER A C   1 
ATOM   2056 O O   . SER A 1 250 ? 29.71200  38.83700  10.83100  1.000 37.95000 ? 251 SER A O   1 
ATOM   2057 C CB  . SER A 1 250 ? 29.90800  35.88400  9.88400   1.000 36.65000 ? 251 SER A CB  1 
ATOM   2058 O OG  . SER A 1 250 ? 29.27700  34.63600  9.95100   1.000 43.18000 ? 251 SER A OG  1 
ATOM   2059 N N   . GLY A 1 251 ? 31.65100  38.06800  11.64300  1.000 32.06000 ? 252 GLY A N   1 
ATOM   2060 C CA  . GLY A 1 251 ? 32.26500  39.37700  11.65100  1.000 37.35000 ? 252 GLY A CA  1 
ATOM   2061 C C   . GLY A 1 251 ? 32.05800  40.14300  12.93500  1.000 40.87000 ? 252 GLY A C   1 
ATOM   2062 O O   . GLY A 1 251 ? 32.71800  41.16100  13.13900  1.000 36.57000 ? 252 GLY A O   1 
ATOM   2063 N N   . GLU A 1 252 ? 31.16000  39.68700  13.80900  1.000 33.89000 ? 253 GLU A N   1 
ATOM   2064 C CA  . GLU A 1 252 ? 30.85100  40.40800  15.03100  1.000 34.81000 ? 253 GLU A CA  1 
ATOM   2065 C C   . GLU A 1 252 ? 31.49700  39.75500  16.25600  1.000 37.88000 ? 253 GLU A C   1 
ATOM   2066 O O   . GLU A 1 252 ? 31.19000  40.16100  17.38700  1.000 30.84000 ? 253 GLU A O   1 
ATOM   2067 C CB  . GLU A 1 252 ? 29.32500  40.49300  15.17700  1.000 38.20000 ? 253 GLU A CB  1 
ATOM   2068 C CG  . GLU A 1 252 ? 28.70200  41.42700  14.15200  1.000 41.58000 ? 253 GLU A CG  1 
ATOM   2069 C CD  . GLU A 1 252 ? 27.31300  41.90000  14.52800  1.000 58.34000 ? 253 GLU A CD  1 
ATOM   2070 O OE1 . GLU A 1 252 ? 26.98600  41.93900  15.73800  1.000 65.69000 ? 253 GLU A OE1 1 
ATOM   2071 O OE2 . GLU A 1 252 ? 26.52600  42.18500  13.59400  1.000 58.74000 ? 253 GLU A OE2 1 
ATOM   2072 N N   . GLU A 1 253 ? 32.43100  38.79700  16.04500  1.000 31.48000 ? 254 GLU A N   1 
ATOM   2073 C CA  . GLU A 1 253 ? 33.03700  38.05600  17.15500  1.000 29.44000 ? 254 GLU A CA  1 
ATOM   2074 C C   . GLU A 1 253 ? 33.76900  38.95200  18.13800  1.000 26.74000 ? 254 GLU A C   1 
ATOM   2075 O O   . GLU A 1 253 ? 33.77900  38.65700  19.32500  1.000 29.00000 ? 254 GLU A O   1 
ATOM   2076 C CB  . GLU A 1 253 ? 33.99100  36.97200  16.64100  1.000 25.34000 ? 254 GLU A CB  1 
ATOM   2077 C CG  . GLU A 1 253 ? 33.31200  35.85400  15.86100  1.000 23.35000 ? 254 GLU A CG  1 
ATOM   2078 C CD  . GLU A 1 253 ? 33.08400  36.18500  14.35500  1.000 34.36000 ? 254 GLU A CD  1 
ATOM   2079 O OE1 . GLU A 1 253 ? 33.36700  37.31300  13.90200  1.000 29.77000 ? 254 GLU A OE1 1 
ATOM   2080 O OE2 . GLU A 1 253 ? 32.56100  35.31500  13.65300  1.000 32.83000 ? 254 GLU A OE2 1 
ATOM   2081 N N   . GLN A 1 254 ? 34.39600  40.04200  17.68300  1.000 24.47000 ? 255 GLN A N   1 
ATOM   2082 C CA  . GLN A 1 254 ? 35.12400  40.89900  18.60600  1.000 29.17000 ? 255 GLN A CA  1 
ATOM   2083 C C   . GLN A 1 254 ? 34.19600  41.59100  19.61300  1.000 28.89000 ? 255 GLN A C   1 
ATOM   2084 O O   . GLN A 1 254 ? 34.66500  42.05100  20.66400  1.000 30.75000 ? 255 GLN A O   1 
ATOM   2085 C CB  . GLN A 1 254 ? 35.98000  41.93300  17.83400  1.000 35.32000 ? 255 GLN A CB  1 
ATOM   2086 C CG  . GLN A 1 254 ? 35.22800  42.85400  16.85300  0.000 33.79000 ? 255 GLN A CG  1 
ATOM   2087 C CD  . GLN A 1 254 ? 34.44000  42.12500  15.77900  0.000 34.39000 ? 255 GLN A CD  1 
ATOM   2088 O OE1 . GLN A 1 254 ? 34.94700  41.21700  15.12000  0.000 34.26000 ? 255 GLN A OE1 1 
ATOM   2089 N NE2 . GLN A 1 254 ? 33.18700  42.52400  15.60100  0.000 35.31000 ? 255 GLN A NE2 1 
ATOM   2090 N N   . ARG A 1 255 ? 32.89300  41.65000  19.33900  1.000 24.99000 ? 256 ARG A N   1 
ATOM   2091 C CA  . ARG A 1 255 ? 31.98300  42.28600  20.28200  1.000 28.90000 ? 256 ARG A CA  1 
ATOM   2092 C C   . ARG A 1 255 ? 31.80400  41.43000  21.53500  1.000 33.05000 ? 256 ARG A C   1 
ATOM   2093 O O   . ARG A 1 255 ? 31.38400  41.93900  22.57500  1.000 31.37000 ? 256 ARG A O   1 
ATOM   2094 C CB  . ARG A 1 255 ? 30.63300  42.50300  19.60500  1.000 31.69000 ? 256 ARG A CB  1 
ATOM   2095 C CG  . ARG A 1 255 ? 30.60000  43.52900  18.41900  1.000 37.25000 ? 256 ARG A CG  1 
ATOM   2096 C CD  . ARG A 1 255 ? 29.14600  43.60200  17.89300  1.000 46.18000 ? 256 ARG A CD  1 
ATOM   2097 N NE  . ARG A 1 255 ? 28.25100  44.27900  18.82300  1.000 48.68000 ? 256 ARG A NE  1 
ATOM   2098 C CZ  . ARG A 1 255 ? 26.93600  44.36700  18.67200  1.000 55.21000 ? 256 ARG A CZ  1 
ATOM   2099 N NH1 . ARG A 1 255 ? 26.30700  43.73900  17.69200  1.000 59.45000 ? 256 ARG A NH1 1 
ATOM   2100 N NH2 . ARG A 1 255 ? 26.22900  45.07900  19.54400  1.000 56.32000 ? 256 ARG A NH2 1 
ATOM   2101 N N   . TYR A 1 256 ? 32.15000  40.15000  21.46300  1.000 26.71000 ? 257 TYR A N   1 
ATOM   2102 C CA  . TYR A 1 256 ? 31.80800  39.18300  22.48900  1.000 21.73000 ? 257 TYR A CA  1 
ATOM   2103 C C   . TYR A 1 256 ? 32.99200  38.83900  23.36000  1.000 22.82000 ? 257 TYR A C   1 
ATOM   2104 O O   . TYR A 1 256 ? 34.11200  38.65300  22.87800  1.000 23.82000 ? 257 TYR A O   1 
ATOM   2105 C CB  . TYR A 1 256 ? 31.27600  37.92800  21.84500  1.000 21.98000 ? 257 TYR A CB  1 
ATOM   2106 C CG  . TYR A 1 256 ? 29.94300  38.13700  21.19700  1.000 28.18000 ? 257 TYR A CG  1 
ATOM   2107 C CD1 . TYR A 1 256 ? 29.83300  38.71000  19.92500  1.000 27.99000 ? 257 TYR A CD1 1 
ATOM   2108 C CD2 . TYR A 1 256 ? 28.77800  37.73200  21.85600  1.000 26.39000 ? 257 TYR A CD2 1 
ATOM   2109 C CE1 . TYR A 1 256 ? 28.59500  38.88600  19.34600  1.000 34.86000 ? 257 TYR A CE1 1 
ATOM   2110 C CE2 . TYR A 1 256 ? 27.54100  37.90200  21.28200  1.000 31.21000 ? 257 TYR A CE2 1 
ATOM   2111 C CZ  . TYR A 1 256 ? 27.45300  38.47100  20.02600  1.000 39.46000 ? 257 TYR A CZ  1 
ATOM   2112 O OH  . TYR A 1 256 ? 26.20400  38.62400  19.45300  1.000 42.19000 ? 257 TYR A OH  1 
ATOM   2113 N N   . THR A 1 257 ? 32.73900  38.74500  24.66100  1.000 23.16000 ? 258 THR A N   1 
ATOM   2114 C CA  . THR A 1 257 ? 33.77700  38.40800  25.62600  1.000 20.83000 ? 258 THR A CA  1 
ATOM   2115 C C   . THR A 1 257 ? 33.19600  37.38000  26.59100  1.000 24.24000 ? 258 THR A C   1 
ATOM   2116 O O   . THR A 1 257 ? 32.00600  37.46500  26.96200  1.000 21.22000 ? 258 THR A O   1 
ATOM   2117 C CB  . THR A 1 257 ? 34.26700  39.61200  26.42500  1.000 26.50000 ? 258 THR A CB  1 
ATOM   2118 O OG1 . THR A 1 257 ? 33.13300  40.33900  26.94700  1.000 25.52000 ? 258 THR A OG1 1 
ATOM   2119 C CG2 . THR A 1 257 ? 35.17900  40.49200  25.57000  1.000 24.56000 ? 258 THR A CG2 1 
ATOM   2120 N N   . CYS A 1 258 ? 34.03200  36.40100  26.96900  1.000 19.31000 ? 259 CYS A N   1 
ATOM   2121 C CA  . CYS A 1 258 ? 33.63300  35.38200  27.92800  1.000 18.65000 ? 259 CYS A CA  1 
ATOM   2122 C C   . CYS A 1 258 ? 34.29700  35.69200  29.26600  1.000 16.98000 ? 259 CYS A C   1 
ATOM   2123 O O   . CYS A 1 258 ? 35.48000  36.06400  29.31500  1.000 22.89000 ? 259 CYS A O   1 
ATOM   2124 C CB  . CYS A 1 258 ? 34.06000  33.99300  27.45400  1.000 19.78000 ? 259 CYS A CB  1 
ATOM   2125 S SG  . CYS A 1 258 ? 33.67600  32.74000  28.73900  1.000 23.91000 ? 259 CYS A SG  1 
ATOM   2126 N N   . HIS A 1 259 ? 33.52700  35.55200  30.33500  1.000 20.45000 ? 260 HIS A N   1 
ATOM   2127 C CA  . HIS A 1 259 ? 33.91800  35.99700  31.66300  1.000 18.91000 ? 260 HIS A CA  1 
ATOM   2128 C C   . HIS A 1 259 ? 33.87000  34.83300  32.62200  1.000 18.66000 ? 260 HIS A C   1 
ATOM   2129 O O   . HIS A 1 259 ? 32.86600  34.13500  32.68900  1.000 19.33000 ? 260 HIS A O   1 
ATOM   2130 C CB  . HIS A 1 259 ? 33.03900  37.12700  32.15600  1.000 25.39000 ? 260 HIS A CB  1 
ATOM   2131 C CG  . HIS A 1 259 ? 33.08000  38.30900  31.25600  1.000 23.22000 ? 260 HIS A CG  1 
ATOM   2132 N ND1 . HIS A 1 259 ? 33.92700  39.36600  31.51100  1.000 26.09000 ? 260 HIS A ND1 1 
ATOM   2133 C CD2 . HIS A 1 259 ? 32.42100  38.61300  30.11100  1.000 28.37000 ? 260 HIS A CD2 1 
ATOM   2134 C CE1 . HIS A 1 259 ? 33.78100  40.27700  30.56300  1.000 27.42000 ? 260 HIS A CE1 1 
ATOM   2135 N NE2 . HIS A 1 259 ? 32.87700  39.84400  29.70200  1.000 25.11000 ? 260 HIS A NE2 1 
ATOM   2136 N N   . VAL A 1 260 ? 34.96000  34.62300  33.33300  1.000 18.27000 ? 261 VAL A N   1 
ATOM   2137 C CA  . VAL A 1 260 ? 35.10700  33.43100  34.15400  1.000 14.82000 ? 261 VAL A CA  1 
ATOM   2138 C C   . VAL A 1 260 ? 35.46700  33.87800  35.56800  1.000 17.58000 ? 261 VAL A C   1 
ATOM   2139 O O   . VAL A 1 260 ? 36.46000  34.58500  35.77200  1.000 22.33000 ? 261 VAL A O   1 
ATOM   2140 C CB  . VAL A 1 260 ? 36.19400  32.50700  33.58600  1.000 18.48000 ? 261 VAL A CB  1 
ATOM   2141 C CG1 . VAL A 1 260 ? 36.15500  31.14000  34.32900  1.000 18.04000 ? 261 VAL A CG1 1 
ATOM   2142 C CG2 . VAL A 1 260 ? 36.01900  32.36200  32.05200  1.000 21.62000 ? 261 VAL A CG2 1 
ATOM   2143 N N   . GLN A 1 261 ? 34.69200  33.41800  36.54800  1.000 18.66000 ? 262 GLN A N   1 
ATOM   2144 C CA  . GLN A 1 261 ? 34.99700  33.62800  37.94900  1.000 23.13000 ? 262 GLN A CA  1 
ATOM   2145 C C   . GLN A 1 261 ? 35.19900  32.26900  38.59200  1.000 18.89000 ? 262 GLN A C   1 
ATOM   2146 O O   . GLN A 1 261 ? 34.36000  31.37100  38.42000  1.000 17.96000 ? 262 GLN A O   1 
ATOM   2147 C CB  . GLN A 1 261 ? 33.85600  34.39100  38.63800  1.000 21.46000 ? 262 GLN A CB  1 
ATOM   2148 C CG  . GLN A 1 261 ? 33.56800  35.73400  37.98800  1.000 29.19000 ? 262 GLN A CG  1 
ATOM   2149 C CD  . GLN A 1 261 ? 32.32800  36.41600  38.54900  1.000 32.24000 ? 262 GLN A CD  1 
ATOM   2150 O OE1 . GLN A 1 261 ? 31.28500  36.40100  37.92300  1.000 50.10000 ? 262 GLN A OE1 1 
ATOM   2151 N NE2 . GLN A 1 261 ? 32.43100  36.96700  39.73400  1.000 41.88000 ? 262 GLN A NE2 1 
ATOM   2152 N N   . HIS A 1 262 ? 36.30700  32.12200  39.30500  1.000 20.76000 ? 263 HIS A N   1 
ATOM   2153 C CA  . HIS A 1 262 ? 36.57600  30.85500  39.97600  1.000 22.62000 ? 263 HIS A CA  1 
ATOM   2154 C C   . HIS A 1 262 ? 37.54900  31.13900  41.08100  1.000 23.20000 ? 263 HIS A C   1 
ATOM   2155 O O   . HIS A 1 262 ? 38.44400  31.97500  40.94900  1.000 24.82000 ? 263 HIS A O   1 
ATOM   2156 C CB  . HIS A 1 262 ? 37.13500  29.78000  39.04200  1.000 17.57000 ? 263 HIS A CB  1 
ATOM   2157 C CG  . HIS A 1 262 ? 37.28800  28.42000  39.68900  1.000 17.79000 ? 263 HIS A CG  1 
ATOM   2158 N ND1 . HIS A 1 262 ? 38.46200  28.01500  40.27800  1.000 16.90000 ? 263 HIS A ND1 1 
ATOM   2159 C CD2 . HIS A 1 262 ? 36.39900  27.39000  39.84600  1.000 15.14000 ? 263 HIS A CD2 1 
ATOM   2160 C CE1 . HIS A 1 262 ? 38.30300  26.78500  40.75200  1.000 19.34000 ? 263 HIS A CE1 1 
ATOM   2161 N NE2 . HIS A 1 262 ? 37.05700  26.38400  40.50800  1.000 15.74000 ? 263 HIS A NE2 1 
ATOM   2162 N N   . GLU A 1 263 ? 37.39600  30.38600  42.14700  1.000 22.21000 ? 264 GLU A N   1 
ATOM   2163 C CA  . GLU A 1 263 ? 38.24500  30.60000  43.30900  1.000 29.88000 ? 264 GLU A CA  1 
ATOM   2164 C C   . GLU A 1 263 ? 39.74100  30.41600  43.00200  1.000 23.66000 ? 264 GLU A C   1 
ATOM   2165 O O   . GLU A 1 263 ? 40.57800  31.03100  43.66500  1.000 24.00000 ? 264 GLU A O   1 
ATOM   2166 C CB  . GLU A 1 263 ? 37.76100  29.67100  44.41800  1.000 27.68000 ? 264 GLU A CB  1 
ATOM   2167 C CG  . GLU A 1 263 ? 38.47500  29.83200  45.75400  1.000 36.22000 ? 264 GLU A CG  1 
ATOM   2168 C CD  . GLU A 1 263 ? 38.27500  28.59200  46.62600  1.000 39.59000 ? 264 GLU A CD  1 
ATOM   2169 O OE1 . GLU A 1 263 ? 37.09900  28.12200  46.69900  1.000 30.30000 ? 264 GLU A OE1 1 
ATOM   2170 O OE2 . GLU A 1 263 ? 39.26700  28.12900  47.24400  1.000 45.59000 ? 264 GLU A OE2 1 
ATOM   2171 N N   . GLY A 1 264 ? 40.10800  29.59900  42.02100  1.000 20.95000 ? 265 GLY A N   1 
ATOM   2172 C CA  . GLY A 1 264 ? 41.52700  29.45200  41.67200  1.000 23.12000 ? 265 GLY A CA  1 
ATOM   2173 C C   . GLY A 1 264 ? 42.12900  30.54200  40.77200  1.000 21.27000 ? 265 GLY A C   1 
ATOM   2174 O O   . GLY A 1 264 ? 43.31200  30.48300  40.42600  1.000 21.59000 ? 265 GLY A O   1 
ATOM   2175 N N   . LEU A 1 265 ? 41.36500  31.43200  40.30500  1.000 20.14000 ? 266 LEU A N   1 
ATOM   2176 C CA  . LEU A 1 265 ? 41.84700  32.57100  39.51300  1.000 27.14000 ? 266 LEU A CA  1 
ATOM   2177 C C   . LEU A 1 265 ? 42.20600  33.73200  40.45100  1.000 31.53000 ? 266 LEU A C   1 
ATOM   2178 O O   . LEU A 1 265 ? 41.34900  34.18000  41.21800  1.000 30.79000 ? 266 LEU A O   1 
ATOM   2179 C CB  . LEU A 1 265 ? 40.75600  33.03400  38.53500  1.000 20.83000 ? 266 LEU A CB  1 
ATOM   2180 C CG  . LEU A 1 265 ? 40.42800  31.99300  37.46200  1.000 24.37000 ? 266 LEU A CG  1 
ATOM   2181 C CD1 . LEU A 1 265 ? 39.14900  32.32000  36.63100  1.000 19.32000 ? 266 LEU A CD1 1 
ATOM   2182 C CD2 . LEU A 1 265 ? 41.61400  31.69800  36.53300  1.000 21.38000 ? 266 LEU A CD2 1 
ATOM   2183 N N   . PRO A 1 266 ? 43.41900  34.28600  40.38800  1.000 37.32000 ? 267 PRO A N   1 
ATOM   2184 C CA  . PRO A 1 266 ? 43.66800  35.51100  41.16600  1.000 32.47000 ? 267 PRO A CA  1 
ATOM   2185 C C   . PRO A 1 266 ? 42.65800  36.61900  40.92900  1.000 40.45000 ? 267 PRO A C   1 
ATOM   2186 O O   . PRO A 1 266 ? 42.29500  37.31800  41.87700  1.000 40.22000 ? 267 PRO A O   1 
ATOM   2187 C CB  . PRO A 1 266 ? 45.08900  35.86600  40.73400  1.000 34.82000 ? 267 PRO A CB  1 
ATOM   2188 C CG  . PRO A 1 266 ? 45.09900  35.57200  39.27000  1.000 49.55000 ? 267 PRO A CG  1 
ATOM   2189 C CD  . PRO A 1 266 ? 44.25800  34.24900  39.17400  1.000 33.25000 ? 267 PRO A CD  1 
ATOM   2190 N N   . GLU A 1 267 ? 42.14100  36.75900  39.71300  1.000 36.53000 ? 268 GLU A N   1 
ATOM   2191 C CA  . GLU A 1 267 ? 41.15700  37.77800  39.38100  1.000 35.89000 ? 268 GLU A CA  1 
ATOM   2192 C C   . GLU A 1 267 ? 40.27400  37.23300  38.26500  1.000 30.12000 ? 268 GLU A C   1 
ATOM   2193 O O   . GLU A 1 267 ? 40.69100  36.31700  37.54100  1.000 30.99000 ? 268 GLU A O   1 
ATOM   2194 C CB  . GLU A 1 267 ? 41.85100  39.09200  38.96900  1.000 33.99000 ? 268 GLU A CB  1 
ATOM   2195 C CG  . GLU A 1 267 ? 42.44000  39.06400  37.57000  1.000 33.22000 ? 268 GLU A CG  1 
ATOM   2196 C CD  . GLU A 1 267 ? 43.26800  40.29700  37.25600  0.000 35.67000 ? 268 GLU A CD  1 
ATOM   2197 O OE1 . GLU A 1 267 ? 44.28400  40.53800  37.94100  0.000 36.59000 ? 268 GLU A OE1 1 
ATOM   2198 O OE2 . GLU A 1 267 ? 42.89100  41.03400  36.32000  0.000 36.47000 ? 268 GLU A OE2 1 
ATOM   2199 N N   . PRO A 1 268 ? 39.04300  37.74200  38.12200  1.000 28.29000 ? 269 PRO A N   1 
ATOM   2200 C CA  . PRO A 1 268 ? 38.15700  37.24300  37.05000  1.000 30.00000 ? 269 PRO A CA  1 
ATOM   2201 C C   . PRO A 1 268 ? 38.81900  37.35900  35.67300  1.000 32.37000 ? 269 PRO A C   1 
ATOM   2202 O O   . PRO A 1 268 ? 39.60400  38.28000  35.42000  1.000 24.30000 ? 269 PRO A O   1 
ATOM   2203 C CB  . PRO A 1 268 ? 36.92200  38.14300  37.15900  1.000 31.97000 ? 269 PRO A CB  1 
ATOM   2204 C CG  . PRO A 1 268 ? 36.94800  38.64200  38.57900  1.000 27.22000 ? 269 PRO A CG  1 
ATOM   2205 C CD  . PRO A 1 268 ? 38.39400  38.77600  38.95300  1.000 29.62000 ? 269 PRO A CD  1 
ATOM   2206 N N   . LEU A 1 269 ? 38.56300  36.36500  34.80900  1.000 22.84000 ? 270 LEU A N   1 
ATOM   2207 C CA  . LEU A 1 269 ? 39.19600  36.32500  33.50400  1.000 28.64000 ? 270 LEU A CA  1 
ATOM   2208 C C   . LEU A 1 269 ? 38.23400  36.87500  32.48700  1.000 20.83000 ? 270 LEU A C   1 
ATOM   2209 O O   . LEU A 1 269 ? 37.02300  36.65900  32.58900  1.000 22.96000 ? 270 LEU A O   1 
ATOM   2210 C CB  . LEU A 1 269 ? 39.56100  34.91800  33.03600  1.000 23.34000 ? 270 LEU A CB  1 
ATOM   2211 C CG  . LEU A 1 269 ? 40.76600  34.12500  33.33400  1.000 30.17000 ? 270 LEU A CG  1 
ATOM   2212 C CD1 . LEU A 1 269 ? 40.53000  32.77300  32.65100  1.000 26.27000 ? 270 LEU A CD1 1 
ATOM   2213 C CD2 . LEU A 1 269 ? 41.90400  34.85800  32.68300  1.000 34.06000 ? 270 LEU A CD2 1 
ATOM   2214 N N   . THR A 1 270 ? 38.78500  37.54300  31.46800  1.000 20.25000 ? 271 THR A N   1 
ATOM   2215 C CA  . THR A 1 270 ? 37.99100  37.90600  30.29600  1.000 24.38000 ? 271 THR A CA  1 
ATOM   2216 C C   . THR A 1 270 ? 38.67800  37.24500  29.11400  1.000 31.19000 ? 271 THR A C   1 
ATOM   2217 O O   . THR A 1 270 ? 39.88400  37.38600  28.97500  1.000 31.01000 ? 271 THR A O   1 
ATOM   2218 C CB  . THR A 1 270 ? 37.94800  39.42400  30.07900  1.000 30.36000 ? 271 THR A CB  1 
ATOM   2219 O OG1 . THR A 1 270 ? 37.28000  40.03600  31.17800  1.000 29.57000 ? 271 THR A OG1 1 
ATOM   2220 C CG2 . THR A 1 270 ? 37.11300  39.73500  28.82800  1.000 27.18000 ? 271 THR A CG2 1 
ATOM   2221 N N   . LEU A 1 271 ? 37.92900  36.51600  28.29000  1.000 25.20000 ? 272 LEU A N   1 
ATOM   2222 C CA  . LEU A 1 271 ? 38.47000  35.82300  27.13300  1.000 25.82000 ? 272 LEU A CA  1 
ATOM   2223 C C   . LEU A 1 271 ? 37.71400  36.19100  25.87000  1.000 27.99000 ? 272 LEU A C   1 
ATOM   2224 O O   . LEU A 1 271 ? 36.53600  36.50500  25.90300  1.000 22.06000 ? 272 LEU A O   1 
ATOM   2225 C CB  . LEU A 1 271 ? 38.32800  34.30500  27.20100  1.000 25.01000 ? 272 LEU A CB  1 
ATOM   2226 C CG  . LEU A 1 271 ? 38.77200  33.38700  28.26500  1.000 35.14000 ? 272 LEU A CG  1 
ATOM   2227 C CD1 . LEU A 1 271 ? 37.71500  33.40700  29.22900  1.000 27.18000 ? 272 LEU A CD1 1 
ATOM   2228 C CD2 . LEU A 1 271 ? 38.82800  32.07200  27.52800  1.000 27.57000 ? 272 LEU A CD2 1 
ATOM   2229 N N   . ARG A 1 272 ? 38.38700  36.04300  24.74700  1.000 26.52000 ? 273 ARG A N   1 
ATOM   2230 C CA  . ARG A 1 272 ? 37.82700  36.28100  23.43800  1.000 26.72000 ? 273 ARG A CA  1 
ATOM   2231 C C   . ARG A 1 272 ? 38.27200  35.15800  22.52500  1.000 23.77000 ? 273 ARG A C   1 
ATOM   2232 O O   . ARG A 1 272 ? 39.27200  34.49100  22.76500  1.000 24.48000 ? 273 ARG A O   1 
ATOM   2233 C CB  . ARG A 1 272 ? 38.30800  37.59800  22.80500  1.000 24.23000 ? 273 ARG A CB  1 
ATOM   2234 C CG  . ARG A 1 272 ? 38.24200  38.78600  23.67500  1.000 39.27000 ? 273 ARG A CG  1 
ATOM   2235 C CD  . ARG A 1 272 ? 38.23600  40.08500  22.84200  1.000 41.62000 ? 273 ARG A CD  1 
ATOM   2236 N NE  . ARG A 1 272 ? 38.21800  41.28300  23.67800  1.000 55.29000 ? 273 ARG A NE  1 
ATOM   2237 C CZ  . ARG A 1 272 ? 38.92200  41.45800  24.79500  1.000 56.64000 ? 273 ARG A CZ  1 
ATOM   2238 N NH1 . ARG A 1 272 ? 39.89200  40.62100  25.15600  1.000 52.30000 ? 273 ARG A NH1 1 
ATOM   2239 N NH2 . ARG A 1 272 ? 38.65700  42.50900  25.56500  1.000 55.20000 ? 273 ARG A NH2 1 
ATOM   2240 N N   . TRP A 1 273 ? 37.57400  35.02800  21.42500  1.000 24.67000 ? 274 TRP A N   1 
ATOM   2241 C CA  . TRP A 1 273 ? 37.96700  34.07600  20.41300  1.000 19.44000 ? 274 TRP A CA  1 
ATOM   2242 C C   . TRP A 1 273 ? 39.40800  34.37900  19.87400  1.000 26.86000 ? 274 TRP A C   1 
ATOM   2243 O O   . TRP A 1 273 ? 39.65000  35.53100  19.54100  1.000 33.95000 ? 274 TRP A O   1 
ATOM   2244 C CB  . TRP A 1 273 ? 36.91000  34.15500  19.31900  1.000 18.97000 ? 274 TRP A CB  1 
ATOM   2245 C CG  . TRP A 1 273 ? 37.22200  33.33100  18.11000  1.000 23.38000 ? 274 TRP A CG  1 
ATOM   2246 C CD1 . TRP A 1 273 ? 37.58700  32.01000  18.08300  1.000 20.27000 ? 274 TRP A CD1 1 
ATOM   2247 C CD2 . TRP A 1 273 ? 37.18700  33.77000  16.77400  1.000 19.25000 ? 274 TRP A CD2 1 
ATOM   2248 N NE1 . TRP A 1 273 ? 37.74000  31.60600  16.79600  1.000 17.98000 ? 274 TRP A NE1 1 
ATOM   2249 C CE2 . TRP A 1 273 ? 37.48900  32.64800  15.96300  1.000 19.00000 ? 274 TRP A CE2 1 
ATOM   2250 C CE3 . TRP A 1 273 ? 36.93800  35.01100  16.16100  1.000 20.77000 ? 274 TRP A CE3 1 
ATOM   2251 C CZ2 . TRP A 1 273 ? 37.59700  32.72500  14.58900  1.000 18.52000 ? 274 TRP A CZ2 1 
ATOM   2252 C CZ3 . TRP A 1 273 ? 37.02400  35.08200  14.75700  1.000 31.35000 ? 274 TRP A CZ3 1 
ATOM   2253 C CH2 . TRP A 1 273 ? 37.34200  33.92500  13.99300  1.000 22.02000 ? 274 TRP A CH2 1 
ATOM   2254 N N   . GLN B 2 2   ? 8.19700   12.98800  41.18500  1.000 27.78000 ? 2   GLN B N   1 
ATOM   2255 C CA  . GLN B 2 2   ? 9.28100   12.35900  40.37100  1.000 18.80000 ? 2   GLN B CA  1 
ATOM   2256 C C   . GLN B 2 2   ? 10.01100  13.36200  39.46800  1.000 27.00000 ? 2   GLN B C   1 
ATOM   2257 O O   . GLN B 2 2   ? 9.46400   14.39900  39.09400  1.000 23.86000 ? 2   GLN B O   1 
ATOM   2258 C CB  . GLN B 2 2   ? 8.75800   11.21900  39.52000  1.000 21.14000 ? 2   GLN B CB  1 
ATOM   2259 C CG  . GLN B 2 2   ? 8.01700   10.17200  40.33000  1.000 21.66000 ? 2   GLN B CG  1 
ATOM   2260 C CD  . GLN B 2 2   ? 7.65900   8.99200   39.44900  1.000 25.42000 ? 2   GLN B CD  1 
ATOM   2261 O OE1 . GLN B 2 2   ? 7.31200   9.13600   38.24600  1.000 27.25000 ? 2   GLN B OE1 1 
ATOM   2262 N NE2 . GLN B 2 2   ? 7.76500   7.81300   40.01200  1.000 25.13000 ? 2   GLN B NE2 1 
ATOM   2263 N N   . ARG B 2 3   ? 11.26800  13.05000  39.14200  1.000 14.73000 ? 3   ARG B N   1 
ATOM   2264 C CA  . ARG B 2 3   ? 12.10700  13.97300  38.40100  1.000 14.17000 ? 3   ARG B CA  1 
ATOM   2265 C C   . ARG B 2 3   ? 12.90300  13.18100  37.37000  1.000 12.86000 ? 3   ARG B C   1 
ATOM   2266 O O   . ARG B 2 3   ? 13.56500  12.18800  37.70500  1.000 13.06000 ? 3   ARG B O   1 
ATOM   2267 C CB  . ARG B 2 3   ? 13.04800  14.76100  39.28600  1.000 17.53000 ? 3   ARG B CB  1 
ATOM   2268 C CG  . ARG B 2 3   ? 12.38900  15.45900  40.47900  1.000 19.86000 ? 3   ARG B CG  1 
ATOM   2269 C CD  . ARG B 2 3   ? 13.51100  16.19200  41.27200  1.000 19.86000 ? 3   ARG B CD  1 
ATOM   2270 N NE  . ARG B 2 3   ? 12.99200  16.54800  42.56300  1.000 26.52000 ? 3   ARG B NE  1 
ATOM   2271 C CZ  . ARG B 2 3   ? 12.16800  17.55500  42.72200  1.000 25.27000 ? 3   ARG B CZ  1 
ATOM   2272 N NH1 . ARG B 2 3   ? 11.90300  18.37800  41.71900  1.000 24.97000 ? 3   ARG B NH1 1 
ATOM   2273 N NH2 . ARG B 2 3   ? 11.57800  17.71700  43.89900  1.000 24.74000 ? 3   ARG B NH2 1 
ATOM   2274 N N   . THR B 2 4   ? 12.78700  13.62500  36.08000  1.000 10.28000 ? 4   THR B N   1 
ATOM   2275 C CA  . THR B 2 4   ? 13.40100  12.87000  34.99900  1.000 16.14000 ? 4   THR B CA  1 
ATOM   2276 C C   . THR B 2 4   ? 14.87600  13.26000  34.97300  1.000 11.66000 ? 4   THR B C   1 
ATOM   2277 O O   . THR B 2 4   ? 15.20900  14.39100  35.30600  1.000 12.90000 ? 4   THR B O   1 
ATOM   2278 C CB  . THR B 2 4   ? 12.68000  13.16300  33.65800  1.000 16.61000 ? 4   THR B CB  1 
ATOM   2279 O OG1 . THR B 2 4   ? 12.97300  12.10800  32.72800  1.000 17.21000 ? 4   THR B OG1 1 
ATOM   2280 C CG2 . THR B 2 4   ? 13.14000  14.46800  33.02300  1.000 18.78000 ? 4   THR B CG2 1 
ATOM   2281 N N   . PRO B 2 5   ? 15.78600  12.36100  34.55900  1.000 10.96000 ? 5   PRO B N   1 
ATOM   2282 C CA  . PRO B 2 5   ? 17.22000  12.70400  34.61800  1.000 11.25000 ? 5   PRO B CA  1 
ATOM   2283 C C   . PRO B 2 5   ? 17.65500  13.71000  33.54200  1.000 16.78000 ? 5   PRO B C   1 
ATOM   2284 O O   . PRO B 2 5   ? 17.24400  13.61200  32.38200  1.000 15.24000 ? 5   PRO B O   1 
ATOM   2285 C CB  . PRO B 2 5   ? 17.90700  11.35300  34.39900  1.000 12.78000 ? 5   PRO B CB  1 
ATOM   2286 C CG  . PRO B 2 5   ? 16.84000  10.45400  33.66100  1.000 10.59000 ? 5   PRO B CG  1 
ATOM   2287 C CD  . PRO B 2 5   ? 15.52700  10.94500  34.24500  1.000 12.16000 ? 5   PRO B CD  1 
ATOM   2288 N N   . LYS B 2 6   ? 18.53600  14.64100  33.92900  1.000 8.91000  ? 6   LYS B N   1 
ATOM   2289 C CA  . LYS B 2 6   ? 19.37600  15.36000  32.97700  1.000 15.97000 ? 6   LYS B CA  1 
ATOM   2290 C C   . LYS B 2 6   ? 20.51100  14.43000  32.54600  1.000 16.18000 ? 6   LYS B C   1 
ATOM   2291 O O   . LYS B 2 6   ? 20.91800  13.55200  33.30400  1.000 13.59000 ? 6   LYS B O   1 
ATOM   2292 C CB  . LYS B 2 6   ? 19.93500  16.62500  33.61700  1.000 15.34000 ? 6   LYS B CB  1 
ATOM   2293 C CG  . LYS B 2 6   ? 18.83500  17.68700  34.07200  1.000 17.59000 ? 6   LYS B CG  1 
ATOM   2294 C CD  . LYS B 2 6   ? 19.50200  18.71700  34.97200  1.000 29.98000 ? 6   LYS B CD  1 
ATOM   2295 C CE  . LYS B 2 6   ? 19.64000  18.20500  36.41100  1.000 28.39000 ? 6   LYS B CE  1 
ATOM   2296 N NZ  . LYS B 2 6   ? 20.50100  19.03900  37.31300  1.000 25.57000 ? 6   LYS B NZ  1 
ATOM   2297 N N   . ILE B 2 7   ? 20.96300  14.56300  31.29500  1.000 12.34000 ? 7   ILE B N   1 
ATOM   2298 C CA  . ILE B 2 7   ? 21.92600  13.62300  30.73500  1.000 10.46000 ? 7   ILE B CA  1 
ATOM   2299 C C   . ILE B 2 7   ? 22.98500  14.43200  30.00800  1.000 13.67000 ? 7   ILE B C   1 
ATOM   2300 O O   . ILE B 2 7   ? 22.64900  15.25000  29.14800  1.000 14.25000 ? 7   ILE B O   1 
ATOM   2301 C CB  . ILE B 2 7   ? 21.25500  12.66100  29.73800  1.000 11.96000 ? 7   ILE B CB  1 
ATOM   2302 C CG1 . ILE B 2 7   ? 20.03500  11.97600  30.36500  1.000 13.08000 ? 7   ILE B CG1 1 
ATOM   2303 C CG2 . ILE B 2 7   ? 22.26100  11.64000  29.18300  1.000 14.05000 ? 7   ILE B CG2 1 
ATOM   2304 C CD1 . ILE B 2 7   ? 19.16500  11.18400  29.24100  1.000 16.96000 ? 7   ILE B CD1 1 
ATOM   2305 N N   . GLN B 2 8   ? 24.24100  14.17000  30.28500  1.000 14.54000 ? 8   GLN B N   1 
ATOM   2306 C CA  . GLN B 2 8   ? 25.31100  14.69100  29.42300  1.000 11.22000 ? 8   GLN B CA  1 
ATOM   2307 C C   . GLN B 2 8   ? 26.27000  13.57300  29.09300  1.000 15.01000 ? 8   GLN B C   1 
ATOM   2308 O O   . GLN B 2 8   ? 26.61300  12.78200  29.97300  1.000 12.90000 ? 8   GLN B O   1 
ATOM   2309 C CB  . GLN B 2 8   ? 26.05500  15.79600  30.13400  1.000 15.71000 ? 8   GLN B CB  1 
ATOM   2310 C CG  . GLN B 2 8   ? 25.29600  17.11900  30.30400  1.000 13.92000 ? 8   GLN B CG  1 
ATOM   2311 C CD  . GLN B 2 8   ? 26.27400  18.25500  30.67000  1.000 13.13000 ? 8   GLN B CD  1 
ATOM   2312 O OE1 . GLN B 2 8   ? 27.08800  18.65900  29.87200  1.000 16.24000 ? 8   GLN B OE1 1 
ATOM   2313 N NE2 . GLN B 2 8   ? 26.15200  18.76800  31.86400  1.000 16.13000 ? 8   GLN B NE2 1 
ATOM   2314 N N   . VAL B 2 9   ? 26.73200  13.51500  27.84000  1.000 15.31000 ? 9   VAL B N   1 
ATOM   2315 C CA  . VAL B 2 9   ? 27.69600  12.50800  27.40000  1.000 13.65000 ? 9   VAL B CA  1 
ATOM   2316 C C   . VAL B 2 9   ? 28.93400  13.24500  26.92000  1.000 15.12000 ? 9   VAL B C   1 
ATOM   2317 O O   . VAL B 2 9   ? 28.79000  14.16800  26.11800  1.000 10.94000 ? 9   VAL B O   1 
ATOM   2318 C CB  . VAL B 2 9   ? 27.16200  11.69200  26.21300  1.000 15.85000 ? 9   VAL B CB  1 
ATOM   2319 C CG1 . VAL B 2 9   ? 28.11900  10.49600  25.96800  1.000 10.99000 ? 9   VAL B CG1 1 
ATOM   2320 C CG2 . VAL B 2 9   ? 25.76900  11.22100  26.53500  1.000 21.29000 ? 9   VAL B CG2 1 
ATOM   2321 N N   . TYR B 2 10  ? 30.12700  12.82600  27.37000  1.000 13.06000 ? 10  TYR B N   1 
ATOM   2322 C CA  . TYR B 2 10  ? 31.28200  13.68200  27.09900  1.000 13.80000 ? 10  TYR B CA  1 
ATOM   2323 C C   . TYR B 2 10  ? 32.52300  12.91700  27.48900  1.000 13.54000 ? 10  TYR B C   1 
ATOM   2324 O O   . TYR B 2 10  ? 32.43200  11.86700  28.13600  1.000 13.32000 ? 10  TYR B O   1 
ATOM   2325 C CB  . TYR B 2 10  ? 31.19300  15.00700  27.87300  1.000 12.40000 ? 10  TYR B CB  1 
ATOM   2326 C CG  . TYR B 2 10  ? 31.04900  14.80800  29.38000  1.000 15.12000 ? 10  TYR B CG  1 
ATOM   2327 C CD1 . TYR B 2 10  ? 29.79300  14.45500  29.95500  1.000 15.02000 ? 10  TYR B CD1 1 
ATOM   2328 C CD2 . TYR B 2 10  ? 32.15100  14.98800  30.25000  1.000 10.95000 ? 10  TYR B CD2 1 
ATOM   2329 C CE1 . TYR B 2 10  ? 29.65600  14.28200  31.30000  1.000 12.85000 ? 10  TYR B CE1 1 
ATOM   2330 C CE2 . TYR B 2 10  ? 31.98400  14.79600  31.64700  1.000 10.18000 ? 10  TYR B CE2 1 
ATOM   2331 C CZ  . TYR B 2 10  ? 30.72700  14.47200  32.15000  1.000 10.94000 ? 10  TYR B CZ  1 
ATOM   2332 O OH  . TYR B 2 10  ? 30.56400  14.30300  33.51700  1.000 14.31000 ? 10  TYR B OH  1 
ATOM   2333 N N   . SER B 2 11  ? 33.70400  13.41200  27.04900  1.000 13.59000 ? 11  SER B N   1 
ATOM   2334 C CA  . SER B 2 11  ? 34.92800  12.69600  27.42000  1.000 14.56000 ? 11  SER B CA  1 
ATOM   2335 C C   . SER B 2 11  ? 35.63300  13.39100  28.58600  1.000 18.25000 ? 11  SER B C   1 
ATOM   2336 O O   . SER B 2 11  ? 35.49700  14.61300  28.79600  1.000 16.21000 ? 11  SER B O   1 
ATOM   2337 C CB  . SER B 2 11  ? 35.88200  12.54100  26.22200  1.000 19.08000 ? 11  SER B CB  1 
ATOM   2338 O OG  . SER B 2 11  ? 36.24700  13.79300  25.72600  1.000 14.11000 ? 11  SER B OG  1 
ATOM   2339 N N   . ARG B 2 12  ? 36.41300  12.59900  29.34400  1.000 13.72000 ? 12  ARG B N   1 
ATOM   2340 C CA  . ARG B 2 12  ? 37.17600  13.18800  30.44800  1.000 13.51000 ? 12  ARG B CA  1 
ATOM   2341 C C   . ARG B 2 12  ? 38.18500  14.21700  29.94000  1.000 17.56000 ? 12  ARG B C   1 
ATOM   2342 O O   . ARG B 2 12  ? 38.29400  15.30300  30.50200  1.000 18.94000 ? 12  ARG B O   1 
ATOM   2343 C CB  . ARG B 2 12  ? 37.88100  12.10300  31.25900  1.000 16.05000 ? 12  ARG B CB  1 
ATOM   2344 C CG  . ARG B 2 12  ? 38.87400  12.65500  32.32400  1.000 17.10000 ? 12  ARG B CG  1 
ATOM   2345 C CD  . ARG B 2 12  ? 39.59700  11.45900  33.06500  1.000 15.00000 ? 12  ARG B CD  1 
ATOM   2346 N NE  . ARG B 2 12  ? 38.62800  10.60600  33.76800  1.000 18.54000 ? 12  ARG B NE  1 
ATOM   2347 C CZ  . ARG B 2 12  ? 38.99400  9.57900   34.51200  1.000 23.76000 ? 12  ARG B CZ  1 
ATOM   2348 N NH1 . ARG B 2 12  ? 40.29200  9.30600   34.72200  1.000 17.97000 ? 12  ARG B NH1 1 
ATOM   2349 N NH2 . ARG B 2 12  ? 38.05900  8.78300   35.02400  1.000 18.93000 ? 12  ARG B NH2 1 
ATOM   2350 N N   . HIS B 2 13  ? 38.93400  13.88900  28.89800  1.000 13.47000 ? 13  HIS B N   1 
ATOM   2351 C CA  . HIS B 2 13  ? 39.95300  14.72400  28.27000  1.000 15.74000 ? 13  HIS B CA  1 
ATOM   2352 C C   . HIS B 2 13  ? 39.57200  15.04600  26.84700  1.000 18.57000 ? 13  HIS B C   1 
ATOM   2353 O O   . HIS B 2 13  ? 38.76700  14.32000  26.23400  1.000 16.76000 ? 13  HIS B O   1 
ATOM   2354 C CB  . HIS B 2 13  ? 41.30600  13.98700  28.27000  1.000 17.54000 ? 13  HIS B CB  1 
ATOM   2355 C CG  . HIS B 2 13  ? 41.75500  13.55200  29.64500  1.000 18.60000 ? 13  HIS B CG  1 
ATOM   2356 N ND1 . HIS B 2 13  ? 42.09400  14.45100  30.63500  1.000 20.56000 ? 13  HIS B ND1 1 
ATOM   2357 C CD2 . HIS B 2 13  ? 41.89000  12.31900  30.20000  1.000 19.28000 ? 13  HIS B CD2 1 
ATOM   2358 C CE1 . HIS B 2 13  ? 42.42200  13.79200  31.73500  1.000 22.84000 ? 13  HIS B CE1 1 
ATOM   2359 N NE2 . HIS B 2 13  ? 42.29800  12.49800  31.50700  1.000 23.44000 ? 13  HIS B NE2 1 
ATOM   2360 N N   . PRO B 2 14  ? 40.17900  16.08400  26.24900  1.000 18.42000 ? 14  PRO B N   1 
ATOM   2361 C CA  . PRO B 2 14  ? 39.85600  16.41300  24.85600  1.000 20.02000 ? 14  PRO B CA  1 
ATOM   2362 C C   . PRO B 2 14  ? 40.17400  15.20000  24.00500  1.000 18.42000 ? 14  PRO B C   1 
ATOM   2363 O O   . PRO B 2 14  ? 41.24500  14.59400  24.15400  1.000 18.25000 ? 14  PRO B O   1 
ATOM   2364 C CB  . PRO B 2 14  ? 40.78900  17.58000  24.53400  1.000 30.96000 ? 14  PRO B CB  1 
ATOM   2365 C CG  . PRO B 2 14  ? 41.06900  18.20800  25.94500  1.000 24.06000 ? 14  PRO B CG  1 
ATOM   2366 C CD  . PRO B 2 14  ? 41.10900  17.04700  26.86400  1.000 21.55000 ? 14  PRO B CD  1 
ATOM   2367 N N   . ALA B 2 15  ? 39.21200  14.81300  23.18300  1.000 17.56000 ? 15  ALA B N   1 
ATOM   2368 C CA  . ALA B 2 15  ? 39.34300  13.59100  22.40600  1.000 23.25000 ? 15  ALA B CA  1 
ATOM   2369 C C   . ALA B 2 15  ? 40.46300  13.71900  21.38400  1.000 18.32000 ? 15  ALA B C   1 
ATOM   2370 O O   . ALA B 2 15  ? 40.49900  14.70600  20.64800  1.000 13.57000 ? 15  ALA B O   1 
ATOM   2371 C CB  . ALA B 2 15  ? 38.04100  13.29900  21.65700  1.000 16.41000 ? 15  ALA B CB  1 
ATOM   2372 N N   . GLU B 2 16  ? 41.31300  12.68900  21.27700  1.000 16.18000 ? 16  GLU B N   1 
ATOM   2373 C CA  . GLU B 2 16  ? 42.31700  12.58000  20.20500  1.000 15.51000 ? 16  GLU B CA  1 
ATOM   2374 C C   . GLU B 2 16  ? 42.27200  11.15900  19.66600  1.000 15.31000 ? 16  GLU B C   1 
ATOM   2375 O O   . GLU B 2 16  ? 42.42200  10.20900  20.44000  1.000 16.28000 ? 16  GLU B O   1 
ATOM   2376 C CB  . GLU B 2 16  ? 43.74500  12.86500  20.70500  1.000 17.60000 ? 16  GLU B CB  1 
ATOM   2377 C CG  . GLU B 2 16  ? 44.03900  14.29500  21.16000  1.000 18.98000 ? 16  GLU B CG  1 
ATOM   2378 C CD  . GLU B 2 16  ? 45.47400  14.44000  21.57800  1.000 20.20000 ? 16  GLU B CD  1 
ATOM   2379 O OE1 . GLU B 2 16  ? 46.35900  14.19500  20.72700  1.000 20.49000 ? 16  GLU B OE1 1 
ATOM   2380 O OE2 . GLU B 2 16  ? 45.75700  14.78000  22.75100  1.000 18.94000 ? 16  GLU B OE2 1 
ATOM   2381 N N   . ASN B 2 17  ? 41.99000  11.00800  18.37400  1.000 14.68000 ? 17  ASN B N   1 
ATOM   2382 C CA  . ASN B 2 17  ? 41.79900  9.67400   17.81300  1.000 14.09000 ? 17  ASN B CA  1 
ATOM   2383 C C   . ASN B 2 17  ? 43.01600  8.78900   18.04900  1.000 22.60000 ? 17  ASN B C   1 
ATOM   2384 O O   . ASN B 2 17  ? 44.18500  9.20200   17.85800  1.000 19.78000 ? 17  ASN B O   1 
ATOM   2385 C CB  . ASN B 2 17  ? 41.50100  9.76200   16.32200  1.000 14.14000 ? 17  ASN B CB  1 
ATOM   2386 C CG  . ASN B 2 17  ? 40.18300  10.35700  16.04500  1.000 20.13000 ? 17  ASN B CG  1 
ATOM   2387 O OD1 . ASN B 2 17  ? 39.22000  10.14900  16.80300  1.000 16.46000 ? 17  ASN B OD1 1 
ATOM   2388 N ND2 . ASN B 2 17  ? 40.07000  11.01700  14.89200  1.000 17.95000 ? 17  ASN B ND2 1 
ATOM   2389 N N   . GLY B 2 18  ? 42.74200  7.58400   18.51800  1.000 15.06000 ? 18  GLY B N   1 
ATOM   2390 C CA  . GLY B 2 18  ? 43.76100  6.62800   18.82200  1.000 17.03000 ? 18  GLY B CA  1 
ATOM   2391 C C   . GLY B 2 18  ? 44.41600  6.80500   20.15600  1.000 21.23000 ? 18  GLY B C   1 
ATOM   2392 O O   . GLY B 2 18  ? 45.34900  6.07200   20.46100  1.000 19.29000 ? 18  GLY B O   1 
ATOM   2393 N N   . LYS B 2 19  ? 43.95800  7.73400   20.98700  1.000 14.28000 ? 19  LYS B N   1 
ATOM   2394 C CA  . LYS B 2 19  ? 44.54000  7.92100   22.31100  1.000 16.08000 ? 19  LYS B CA  1 
ATOM   2395 C C   . LYS B 2 19  ? 43.53200  7.51000   23.38600  1.000 22.77000 ? 19  LYS B C   1 
ATOM   2396 O O   . LYS B 2 19  ? 42.35500  7.91500   23.31700  1.000 17.98000 ? 19  LYS B O   1 
ATOM   2397 C CB  . LYS B 2 19  ? 44.95200  9.38900   22.50600  1.000 16.41000 ? 19  LYS B CB  1 
ATOM   2398 C CG  . LYS B 2 19  ? 46.04000  9.89600   21.41500  1.000 21.59000 ? 19  LYS B CG  1 
ATOM   2399 C CD  . LYS B 2 19  ? 47.39500  9.54700   21.81400  1.000 26.25000 ? 19  LYS B CD  1 
ATOM   2400 C CE  . LYS B 2 19  ? 48.52200  10.20300  20.92700  1.000 22.00000 ? 19  LYS B CE  1 
ATOM   2401 N NZ  . LYS B 2 19  ? 48.04500  10.16600  19.51200  1.000 31.97000 ? 19  LYS B NZ  1 
ATOM   2402 N N   . SER B 2 20  ? 43.99200  6.74500   24.39500  1.000 15.45000 ? 20  SER B N   1 
ATOM   2403 C CA  . SER B 2 20  ? 43.04400  6.27000   25.39700  1.000 21.12000 ? 20  SER B CA  1 
ATOM   2404 C C   . SER B 2 20  ? 42.47500  7.46100   26.17800  1.000 20.85000 ? 20  SER B C   1 
ATOM   2405 O O   . SER B 2 20  ? 43.15400  8.47100   26.40100  1.000 18.20000 ? 20  SER B O   1 
ATOM   2406 C CB  . SER B 2 20  ? 43.72400  5.27400   26.36500  1.000 20.06000 ? 20  SER B CB  1 
ATOM   2407 O OG  . SER B 2 20  ? 42.75000  4.71900   27.24000  1.000 28.31000 ? 20  SER B OG  1 
ATOM   2408 N N   . ASN B 2 21  ? 41.23800  7.31300   26.63700  1.000 19.58000 ? 21  ASN B N   1 
ATOM   2409 C CA  . ASN B 2 21  ? 40.46100  8.40800   27.23600  1.000 17.81000 ? 21  ASN B CA  1 
ATOM   2410 C C   . ASN B 2 21  ? 39.37800  7.75100   28.09300  1.000 14.84000 ? 21  ASN B C   1 
ATOM   2411 O O   . ASN B 2 21  ? 39.37400  6.53500   28.25900  1.000 11.56000 ? 21  ASN B O   1 
ATOM   2412 C CB  . ASN B 2 21  ? 39.87500  9.29800   26.14300  1.000 15.44000 ? 21  ASN B CB  1 
ATOM   2413 C CG  . ASN B 2 21  ? 39.53700  10.75300  26.58700  1.000 13.43000 ? 21  ASN B CG  1 
ATOM   2414 O OD1 . ASN B 2 21  ? 39.12000  11.01200  27.71200  1.000 14.68000 ? 21  ASN B OD1 1 
ATOM   2415 N ND2 . ASN B 2 21  ? 39.74700  11.71300  25.66600  1.000 15.65000 ? 21  ASN B ND2 1 
ATOM   2416 N N   . PHE B 2 22  ? 38.42900  8.54600   28.59700  1.000 12.35000 ? 22  PHE B N   1 
ATOM   2417 C CA  . PHE B 2 22  ? 37.29000  8.00700   29.34000  1.000 17.08000 ? 22  PHE B CA  1 
ATOM   2418 C C   . PHE B 2 22  ? 36.01800  8.63000   28.76400  1.000 12.64000 ? 22  PHE B C   1 
ATOM   2419 O O   . PHE B 2 22  ? 35.94400  9.84400   28.56800  1.000 12.64000 ? 22  PHE B O   1 
ATOM   2420 C CB  . PHE B 2 22  ? 37.35600  8.28400   30.85700  1.000 17.23000 ? 22  PHE B CB  1 
ATOM   2421 C CG  . PHE B 2 22  ? 38.28300  7.37100   31.58100  1.000 20.80000 ? 22  PHE B CG  1 
ATOM   2422 C CD1 . PHE B 2 22  ? 39.64000  7.68500   31.65800  1.000 22.55000 ? 22  PHE B CD1 1 
ATOM   2423 C CD2 . PHE B 2 22  ? 37.81500  6.21600   32.17500  1.000 21.51000 ? 22  PHE B CD2 1 
ATOM   2424 C CE1 . PHE B 2 22  ? 40.54300  6.85800   32.30600  1.000 28.31000 ? 22  PHE B CE1 1 
ATOM   2425 C CE2 . PHE B 2 22  ? 38.69600  5.37100   32.84400  1.000 32.99000 ? 22  PHE B CE2 1 
ATOM   2426 C CZ  . PHE B 2 22  ? 40.09600  5.70400   32.89700  1.000 25.89000 ? 22  PHE B CZ  1 
ATOM   2427 N N   . LEU B 2 23  ? 35.06100  7.79100   28.45400  1.000 14.34000 ? 23  LEU B N   1 
ATOM   2428 C CA  . LEU B 2 23  ? 33.72700  8.20500   28.00200  1.000 11.57000 ? 23  LEU B CA  1 
ATOM   2429 C C   . LEU B 2 23  ? 32.81800  8.25400   29.22000  1.000 13.38000 ? 23  LEU B C   1 
ATOM   2430 O O   . LEU B 2 23  ? 32.64300  7.22500   29.87600  1.000 11.08000 ? 23  LEU B O   1 
ATOM   2431 C CB  . LEU B 2 23  ? 33.21100  7.18100   26.99400  1.000 13.93000 ? 23  LEU B CB  1 
ATOM   2432 C CG  . LEU B 2 23  ? 31.78500  7.47400   26.51500  1.000 13.46000 ? 23  LEU B CG  1 
ATOM   2433 C CD1 . LEU B 2 23  ? 31.74300  8.83500   25.79400  1.000 14.82000 ? 23  LEU B CD1 1 
ATOM   2434 C CD2 . LEU B 2 23  ? 31.32900  6.33600   25.61600  1.000 16.23000 ? 23  LEU B CD2 1 
ATOM   2435 N N   . ASN B 2 24  ? 32.16900  9.42300   29.45200  1.000 10.69000 ? 24  ASN B N   1 
ATOM   2436 C CA  . ASN B 2 24  ? 31.35100  9.66900   30.63100  1.000 12.79000 ? 24  ASN B CA  1 
ATOM   2437 C C   . ASN B 2 24  ? 29.90600  9.81400   30.19900  1.000 14.09000 ? 24  ASN B C   1 
ATOM   2438 O O   . ASN B 2 24  ? 29.62300  10.46000  29.17900  1.000 10.32000 ? 24  ASN B O   1 
ATOM   2439 C CB  . ASN B 2 24  ? 31.75400  10.96900  31.33300  1.000 11.06000 ? 24  ASN B CB  1 
ATOM   2440 C CG  . ASN B 2 24  ? 33.11600  10.86600  31.96200  1.000 11.66000 ? 24  ASN B CG  1 
ATOM   2441 O OD1 . ASN B 2 24  ? 33.55400  9.75800   32.25100  1.000 16.05000 ? 24  ASN B OD1 1 
ATOM   2442 N ND2 . ASN B 2 24  ? 33.80600  12.02100  32.20800  1.000 11.18000 ? 24  ASN B ND2 1 
ATOM   2443 N N   . CYS B 2 25  ? 28.98700  9.32500   31.04200  1.000 12.35000 ? 25  CYS B N   1 
ATOM   2444 C CA  . CYS B 2 25  ? 27.58400  9.69800   30.89900  1.000 10.90000 ? 25  CYS B CA  1 
ATOM   2445 C C   . CYS B 2 25  ? 27.15000  10.14900  32.28000  1.000 12.18000 ? 25  CYS B C   1 
ATOM   2446 O O   . CYS B 2 25  ? 27.11100  9.32800   33.19800  1.000 11.52000 ? 25  CYS B O   1 
ATOM   2447 C CB  . CYS B 2 25  ? 26.73400  8.52800   30.43400  1.000 13.43000 ? 25  CYS B CB  1 
ATOM   2448 S SG  . CYS B 2 25  ? 24.94600  9.04500   30.23700  1.000 16.38000 ? 25  CYS B SG  1 
ATOM   2449 N N   . TYR B 2 26  ? 26.81100  11.42600  32.42200  1.000 12.06000 ? 26  TYR B N   1 
ATOM   2450 C CA  . TYR B 2 26  ? 26.45400  12.00300  33.72600  1.000 10.82000 ? 26  TYR B CA  1 
ATOM   2451 C C   . TYR B 2 26  ? 24.94900  12.19900  33.78500  1.000 11.52000 ? 26  TYR B C   1 
ATOM   2452 O O   . TYR B 2 26  ? 24.37900  12.92800  32.94700  1.000 12.13000 ? 26  TYR B O   1 
ATOM   2453 C CB  . TYR B 2 26  ? 27.15300  13.34400  33.92700  1.000 9.78000  ? 26  TYR B CB  1 
ATOM   2454 C CG  . TYR B 2 26  ? 26.87700  14.01800  35.28100  1.000 12.11000 ? 26  TYR B CG  1 
ATOM   2455 C CD1 . TYR B 2 26  ? 27.23800  13.38400  36.43700  1.000 14.81000 ? 26  TYR B CD1 1 
ATOM   2456 C CD2 . TYR B 2 26  ? 26.32500  15.28900  35.37100  1.000 16.37000 ? 26  TYR B CD2 1 
ATOM   2457 C CE1 . TYR B 2 26  ? 27.03600  13.96100  37.67500  1.000 17.28000 ? 26  TYR B CE1 1 
ATOM   2458 C CE2 . TYR B 2 26  ? 26.09800  15.90900  36.64800  1.000 17.69000 ? 26  TYR B CE2 1 
ATOM   2459 C CZ  . TYR B 2 26  ? 26.47200  15.20900  37.77700  1.000 19.29000 ? 26  TYR B CZ  1 
ATOM   2460 O OH  . TYR B 2 26  ? 26.27700  15.70700  39.06000  1.000 19.59000 ? 26  TYR B OH  1 
ATOM   2461 N N   . VAL B 2 27  ? 24.29200  11.51700  34.73000  1.000 12.57000 ? 27  VAL B N   1 
ATOM   2462 C CA  . VAL B 2 27  ? 22.84900  11.61400  34.91700  1.000 9.36000  ? 27  VAL B CA  1 
ATOM   2463 C C   . VAL B 2 27  ? 22.58900  12.27900  36.28200  1.000 9.82000  ? 27  VAL B C   1 
ATOM   2464 O O   . VAL B 2 27  ? 23.24100  11.95500  37.27300  1.000 14.83000 ? 27  VAL B O   1 
ATOM   2465 C CB  . VAL B 2 27  ? 22.14700  10.23400  34.80300  1.000 13.50000 ? 27  VAL B CB  1 
ATOM   2466 C CG1 . VAL B 2 27  ? 22.07500  9.71100   33.31300  1.000 15.07000 ? 27  VAL B CG1 1 
ATOM   2467 C CG2 . VAL B 2 27  ? 22.77900  9.19500   35.72100  1.000 14.41000 ? 27  VAL B CG2 1 
ATOM   2468 N N   . SER B 2 28  ? 21.68900  13.25400  36.33700  1.000 10.62000 ? 28  SER B N   1 
ATOM   2469 C CA  . SER B 2 28  ? 21.54200  14.03000  37.56200  1.000 13.67000 ? 28  SER B CA  1 
ATOM   2470 C C   . SER B 2 28  ? 20.11900  14.56500  37.69500  1.000 12.91000 ? 28  SER B C   1 
ATOM   2471 O O   . SER B 2 28  ? 19.35700  14.59000  36.73700  1.000 13.90000 ? 28  SER B O   1 
ATOM   2472 C CB  . SER B 2 28  ? 22.56300  15.19500  37.61700  1.000 17.97000 ? 28  SER B CB  1 
ATOM   2473 O OG  . SER B 2 28  ? 22.40600  16.01500  36.46600  1.000 16.41000 ? 28  SER B OG  1 
ATOM   2474 N N   . GLY B 2 29  ? 19.77500  15.02300  38.88200  1.000 11.15000 ? 29  GLY B N   1 
ATOM   2475 C CA  . GLY B 2 29  ? 18.45800  15.63900  39.03000  1.000 10.98000 ? 29  GLY B CA  1 
ATOM   2476 C C   . GLY B 2 29  ? 17.27100  14.68500  39.00000  1.000 13.67000 ? 29  GLY B C   1 
ATOM   2477 O O   . GLY B 2 29  ? 16.14600  15.14100  38.81300  1.000 15.81000 ? 29  GLY B O   1 
ATOM   2478 N N   . PHE B 2 30  ? 17.47500  13.37600  39.20300  1.000 10.97000 ? 30  PHE B N   1 
ATOM   2479 C CA  . PHE B 2 30  ? 16.39900  12.40400  39.02200  1.000 13.09000 ? 30  PHE B CA  1 
ATOM   2480 C C   . PHE B 2 30  ? 15.93200  11.80100  40.35100  1.000 14.10000 ? 30  PHE B C   1 
ATOM   2481 O O   . PHE B 2 30  ? 16.63400  11.82700  41.34400  1.000 13.79000 ? 30  PHE B O   1 
ATOM   2482 C CB  . PHE B 2 30  ? 16.79000  11.28300  38.03000  1.000 11.55000 ? 30  PHE B CB  1 
ATOM   2483 C CG  . PHE B 2 30  ? 18.02200  10.48900  38.40300  1.000 12.42000 ? 30  PHE B CG  1 
ATOM   2484 C CD1 . PHE B 2 30  ? 19.25600  10.95700  38.06800  1.000 13.20000 ? 30  PHE B CD1 1 
ATOM   2485 C CD2 . PHE B 2 30  ? 17.91200  9.27900   39.10300  1.000 13.14000 ? 30  PHE B CD2 1 
ATOM   2486 C CE1 . PHE B 2 30  ? 20.41000  10.22200  38.39400  1.000 13.98000 ? 30  PHE B CE1 1 
ATOM   2487 C CE2 . PHE B 2 30  ? 19.04700  8.51800   39.46200  1.000 9.55000  ? 30  PHE B CE2 1 
ATOM   2488 C CZ  . PHE B 2 30  ? 20.30900  9.01500   39.07800  1.000 8.42000  ? 30  PHE B CZ  1 
ATOM   2489 N N   . HIS B 2 31  ? 14.67100  11.31400  40.36300  1.000 10.98000 ? 31  HIS B N   1 
ATOM   2490 C CA  . HIS B 2 31  ? 14.06400  10.68800  41.52600  1.000 13.67000 ? 31  HIS B CA  1 
ATOM   2491 C C   . HIS B 2 31  ? 12.89300  9.89900   40.96200  1.000 11.85000 ? 31  HIS B C   1 
ATOM   2492 O O   . HIS B 2 31  ? 12.09200  10.46700  40.22200  1.000 15.76000 ? 31  HIS B O   1 
ATOM   2493 C CB  . HIS B 2 31  ? 13.60500  11.70700  42.57000  1.000 15.02000 ? 31  HIS B CB  1 
ATOM   2494 C CG  . HIS B 2 31  ? 13.64600  11.18200  43.97200  1.000 14.51000 ? 31  HIS B CG  1 
ATOM   2495 N ND1 . HIS B 2 31  ? 12.76600  10.22300  44.44900  1.000 13.31000 ? 31  HIS B ND1 1 
ATOM   2496 C CD2 . HIS B 2 31  ? 14.50100  11.45500  44.99800  1.000 12.96000 ? 31  HIS B CD2 1 
ATOM   2497 C CE1 . HIS B 2 31  ? 13.07200  9.92000   45.70900  1.000 13.27000 ? 31  HIS B CE1 1 
ATOM   2498 N NE2 . HIS B 2 31  ? 14.11200  10.67400  46.07600  1.000 12.87000 ? 31  HIS B NE2 1 
ATOM   2499 N N   . PRO B 2 32  ? 12.75800  8.64200   41.28100  1.000 14.68000 ? 32  PRO B N   1 
ATOM   2500 C CA  . PRO B 2 32  ? 13.54900  7.86500   42.26600  1.000 14.90000 ? 32  PRO B CA  1 
ATOM   2501 C C   . PRO B 2 32  ? 14.92000  7.44100   41.75300  1.000 15.02000 ? 32  PRO B C   1 
ATOM   2502 O O   . PRO B 2 32  ? 15.26300  7.75100   40.60500  1.000 12.28000 ? 32  PRO B O   1 
ATOM   2503 C CB  . PRO B 2 32  ? 12.67500  6.62600   42.53400  1.000 15.17000 ? 32  PRO B CB  1 
ATOM   2504 C CG  . PRO B 2 32  ? 11.91200  6.43300   41.19000  1.000 15.72000 ? 32  PRO B CG  1 
ATOM   2505 C CD  . PRO B 2 32  ? 11.66300  7.84300   40.67700  1.000 16.71000 ? 32  PRO B CD  1 
ATOM   2506 N N   . SER B 2 33  ? 15.69300  6.66600   42.52800  1.000 12.70000 ? 33  SER B N   1 
ATOM   2507 C CA  . SER B 2 33  ? 17.07100  6.38900   42.14100  1.000 11.80000 ? 33  SER B CA  1 
ATOM   2508 C C   . SER B 2 33  ? 17.20800  5.27700   41.10900  1.000 14.02000 ? 33  SER B C   1 
ATOM   2509 O O   . SER B 2 33  ? 18.27000  5.15500   40.51300  1.000 12.59000 ? 33  SER B O   1 
ATOM   2510 C CB  . SER B 2 33  ? 17.92000  6.02700   43.41000  1.000 12.50000 ? 33  SER B CB  1 
ATOM   2511 O OG  . SER B 2 33  ? 17.41600  4.82500   44.01600  1.000 13.53000 ? 33  SER B OG  1 
ATOM   2512 N N   . ASP B 2 34  ? 16.22500  4.37100   40.94400  1.000 14.91000 ? 34  ASP B N   1 
ATOM   2513 C CA  . ASP B 2 34  ? 16.45300  3.31100   39.96200  1.000 14.69000 ? 34  ASP B CA  1 
ATOM   2514 C C   . ASP B 2 34  ? 16.57100  3.90900   38.56700  1.000 14.69000 ? 34  ASP B C   1 
ATOM   2515 O O   . ASP B 2 34  ? 15.72500  4.70500   38.14700  1.000 14.62000 ? 34  ASP B O   1 
ATOM   2516 C CB  . ASP B 2 34  ? 15.34000  2.26800   39.91900  1.000 19.05000 ? 34  ASP B CB  1 
ATOM   2517 C CG  . ASP B 2 34  ? 15.29900  1.41600   41.14200  1.000 40.23000 ? 34  ASP B CG  1 
ATOM   2518 O OD1 . ASP B 2 34  ? 16.39000  0.98100   41.61800  1.000 45.84000 ? 34  ASP B OD1 1 
ATOM   2519 O OD2 . ASP B 2 34  ? 14.17300  1.24000   41.65000  1.000 45.18000 ? 34  ASP B OD2 1 
ATOM   2520 N N   . ILE B 2 35  ? 17.59200  3.49200   37.82500  1.000 12.34000 ? 35  ILE B N   1 
ATOM   2521 C CA  . ILE B 2 35  ? 17.83800  4.10400   36.51900  1.000 13.00000 ? 35  ILE B CA  1 
ATOM   2522 C C   . ILE B 2 35  ? 18.63400  3.08200   35.72800  1.000 17.26000 ? 35  ILE B C   1 
ATOM   2523 O O   . ILE B 2 35  ? 19.39100  2.30700   36.30800  1.000 15.78000 ? 35  ILE B O   1 
ATOM   2524 C CB  . ILE B 2 35  ? 18.58600  5.46000   36.69300  1.000 14.04000 ? 35  ILE B CB  1 
ATOM   2525 C CG1 . ILE B 2 35  ? 18.65800  6.23500   35.39000  1.000 12.15000 ? 35  ILE B CG1 1 
ATOM   2526 C CG2 . ILE B 2 35  ? 19.99300  5.31300   37.37500  1.000 14.46000 ? 35  ILE B CG2 1 
ATOM   2527 C CD1 . ILE B 2 35  ? 18.99500  7.75000   35.57100  1.000 12.73000 ? 35  ILE B CD1 1 
ATOM   2528 N N   . GLU B 2 36  ? 18.41200  3.02200   34.40500  1.000 11.76000 ? 36  GLU B N   1 
ATOM   2529 C CA  . GLU B 2 36  ? 19.24300  2.15900   33.57100  1.000 12.83000 ? 36  GLU B CA  1 
ATOM   2530 C C   . GLU B 2 36  ? 20.05800  3.05500   32.67900  1.000 18.86000 ? 36  GLU B C   1 
ATOM   2531 O O   . GLU B 2 36  ? 19.49400  3.92500   31.99300  1.000 14.88000 ? 36  GLU B O   1 
ATOM   2532 C CB  . GLU B 2 36  ? 18.44200  1.23200   32.67500  1.000 17.35000 ? 36  GLU B CB  1 
ATOM   2533 C CG  . GLU B 2 36  ? 17.48400  0.37100   33.35700  1.000 33.64000 ? 36  GLU B CG  1 
ATOM   2534 C CD  . GLU B 2 36  ? 16.66300  -0.35900  32.28200  1.000 43.64000 ? 36  GLU B CD  1 
ATOM   2535 O OE1 . GLU B 2 36  ? 17.32000  -1.13100  31.53600  1.000 43.79000 ? 36  GLU B OE1 1 
ATOM   2536 O OE2 . GLU B 2 36  ? 15.41700  -0.12600  32.18900  1.000 40.98000 ? 36  GLU B OE2 1 
ATOM   2537 N N   . VAL B 2 37  ? 21.37900  2.87600   32.71300  1.000 14.68000 ? 37  VAL B N   1 
ATOM   2538 C CA  . VAL B 2 37  ? 22.26000  3.70200   31.90300  1.000 15.87000 ? 37  VAL B CA  1 
ATOM   2539 C C   . VAL B 2 37  ? 23.22100  2.76200   31.17100  1.000 17.21000 ? 37  VAL B C   1 
ATOM   2540 O O   . VAL B 2 37  ? 23.88700  1.94100   31.81000  1.000 14.97000 ? 37  VAL B O   1 
ATOM   2541 C CB  . VAL B 2 37  ? 23.05000  4.69800   32.75800  1.000 18.12000 ? 37  VAL B CB  1 
ATOM   2542 C CG1 . VAL B 2 37  ? 24.00400  5.52200   31.85900  1.000 12.02000 ? 37  VAL B CG1 1 
ATOM   2543 C CG2 . VAL B 2 37  ? 22.08300  5.61800   33.65000  1.000 14.42000 ? 37  VAL B CG2 1 
ATOM   2544 N N   . ASP B 2 38  ? 23.23500  2.82300   29.83200  1.000 16.33000 ? 38  ASP B N   1 
ATOM   2545 C CA  . ASP B 2 38  ? 24.20100  2.03500   29.07600  1.000 15.30000 ? 38  ASP B CA  1 
ATOM   2546 C C   . ASP B 2 38  ? 25.02200  2.99300   28.23400  1.000 16.21000 ? 38  ASP B C   1 
ATOM   2547 O O   . ASP B 2 38  ? 24.50300  4.01100   27.78700  1.000 16.36000 ? 38  ASP B O   1 
ATOM   2548 C CB  . ASP B 2 38  ? 23.55400  1.00400   28.20400  1.000 17.31000 ? 38  ASP B CB  1 
ATOM   2549 C CG  . ASP B 2 38  ? 22.98000  -0.16300  29.03000  1.000 29.28000 ? 38  ASP B CG  1 
ATOM   2550 O OD1 . ASP B 2 38  ? 23.71100  -0.85500  29.78800  1.000 31.14000 ? 38  ASP B OD1 1 
ATOM   2551 O OD2 . ASP B 2 38  ? 21.76800  -0.30500  28.95900  1.000 27.12000 ? 38  ASP B OD2 1 
ATOM   2552 N N   . LEU B 2 39  ? 26.29800  2.67900   28.08900  1.000 13.93000 ? 39  LEU B N   1 
ATOM   2553 C CA  . LEU B 2 39  ? 27.14400  3.32200   27.09600  1.000 11.80000 ? 39  LEU B CA  1 
ATOM   2554 C C   . LEU B 2 39  ? 27.12800  2.40900   25.88600  1.000 12.87000 ? 39  LEU B C   1 
ATOM   2555 O O   . LEU B 2 39  ? 27.37000  1.20100   26.03800  1.000 17.77000 ? 39  LEU B O   1 
ATOM   2556 C CB  . LEU B 2 39  ? 28.58600  3.47500   27.63000  1.000 13.45000 ? 39  LEU B CB  1 
ATOM   2557 C CG  . LEU B 2 39  ? 28.59000  4.45600   28.80900  1.000 20.05000 ? 39  LEU B CG  1 
ATOM   2558 C CD1 . LEU B 2 39  ? 29.98900  4.58400   29.45300  1.000 18.47000 ? 39  LEU B CD1 1 
ATOM   2559 C CD2 . LEU B 2 39  ? 28.04700  5.83300   28.34100  1.000 22.20000 ? 39  LEU B CD2 1 
ATOM   2560 N N   . LEU B 2 40  ? 26.91800  2.97800   24.69300  1.000 13.18000 ? 40  LEU B N   1 
ATOM   2561 C CA  . LEU B 2 40  ? 26.86600  2.19600   23.46000  1.000 12.75000 ? 40  LEU B CA  1 
ATOM   2562 C C   . LEU B 2 40  ? 28.04600  2.52200   22.56000  1.000 14.66000 ? 40  LEU B C   1 
ATOM   2563 O O   . LEU B 2 40  ? 28.41200  3.68900   22.41600  1.000 14.37000 ? 40  LEU B O   1 
ATOM   2564 C CB  . LEU B 2 40  ? 25.60000  2.49700   22.66600  1.000 14.94000 ? 40  LEU B CB  1 
ATOM   2565 C CG  . LEU B 2 40  ? 24.30900  2.49700   23.50500  1.000 15.26000 ? 40  LEU B CG  1 
ATOM   2566 C CD1 . LEU B 2 40  ? 23.10800  2.82300   22.64900  1.000 13.23000 ? 40  LEU B CD1 1 
ATOM   2567 C CD2 . LEU B 2 40  ? 24.20300  1.11300   24.14500  1.000 18.44000 ? 40  LEU B CD2 1 
ATOM   2568 N N   . LYS B 2 41  ? 28.62000  1.49200   21.93700  1.000 13.04000 ? 41  LYS B N   1 
ATOM   2569 C CA  . LYS B 2 41  ? 29.59000  1.68800   20.85300  1.000 12.93000 ? 41  LYS B CA  1 
ATOM   2570 C C   . LYS B 2 41  ? 28.97900  1.13800   19.56900  1.000 17.88000 ? 41  LYS B C   1 
ATOM   2571 O O   . LYS B 2 41  ? 28.71200  -0.07000  19.48800  1.000 18.80000 ? 41  LYS B O   1 
ATOM   2572 C CB  . LYS B 2 41  ? 30.88700  0.93400   21.16400  1.000 16.13000 ? 41  LYS B CB  1 
ATOM   2573 C CG  . LYS B 2 41  ? 31.86900  0.95000   19.95400  1.000 17.29000 ? 41  LYS B CG  1 
ATOM   2574 C CD  . LYS B 2 41  ? 33.15100  0.23700   20.34600  1.000 14.46000 ? 41  LYS B CD  1 
ATOM   2575 C CE  . LYS B 2 41  ? 34.22600  0.35100   19.21100  1.000 19.18000 ? 41  LYS B CE  1 
ATOM   2576 N NZ  . LYS B 2 41  ? 35.36700  -0.49800  19.66300  1.000 20.47000 ? 41  LYS B NZ  1 
ATOM   2577 N N   . ASN B 2 42  ? 28.79100  2.00700   18.56200  1.000 15.74000 ? 42  ASN B N   1 
ATOM   2578 C CA  . ASN B 2 42  ? 28.12700  1.64300   17.28800  1.000 20.50000 ? 42  ASN B CA  1 
ATOM   2579 C C   . ASN B 2 42  ? 26.81600  0.90000   17.54100  1.000 20.62000 ? 42  ASN B C   1 
ATOM   2580 O O   . ASN B 2 42  ? 26.48900  -0.09000  16.87200  1.000 21.05000 ? 42  ASN B O   1 
ATOM   2581 C CB  . ASN B 2 42  ? 29.07100  0.83000   16.40600  1.000 21.11000 ? 42  ASN B CB  1 
ATOM   2582 C CG  . ASN B 2 42  ? 30.29300  1.61700   16.08200  1.000 19.37000 ? 42  ASN B CG  1 
ATOM   2583 O OD1 . ASN B 2 42  ? 30.16400  2.79200   15.73700  1.000 18.74000 ? 42  ASN B OD1 1 
ATOM   2584 N ND2 . ASN B 2 42  ? 31.46900  1.01900   16.22000  1.000 16.10000 ? 42  ASN B ND2 1 
ATOM   2585 N N   . GLY B 2 43  ? 26.05800  1.41100   18.50700  1.000 20.88000 ? 43  GLY B N   1 
ATOM   2586 C CA  . GLY B 2 43  ? 24.74000  0.89800   18.83600  1.000 22.14000 ? 43  GLY B CA  1 
ATOM   2587 C C   . GLY B 2 43  ? 24.72100  -0.26000  19.80600  1.000 19.47000 ? 43  GLY B C   1 
ATOM   2588 O O   . GLY B 2 43  ? 23.62000  -0.69500  20.18700  1.000 21.65000 ? 43  GLY B O   1 
ATOM   2589 N N   . GLU B 2 44  ? 25.87300  -0.82400  20.17000  1.000 17.27000 ? 44  GLU B N   1 
ATOM   2590 C CA  . GLU B 2 44  ? 25.94200  -2.02600  20.99100  1.000 26.23000 ? 44  GLU B CA  1 
ATOM   2591 C C   . GLU B 2 44  ? 26.38500  -1.69300  22.41600  1.000 24.46000 ? 44  GLU B C   1 
ATOM   2592 O O   . GLU B 2 44  ? 27.30100  -0.89600  22.62700  1.000 19.24000 ? 44  GLU B O   1 
ATOM   2593 C CB  . GLU B 2 44  ? 26.89700  -3.06000  20.37600  1.000 24.41000 ? 44  GLU B CB  1 
ATOM   2594 C CG  . GLU B 2 44  ? 26.49600  -3.44800  18.90200  1.000 25.89000 ? 44  GLU B CG  1 
ATOM   2595 C CD  . GLU B 2 44  ? 25.17700  -4.26600  18.80200  1.000 46.79000 ? 44  GLU B CD  1 
ATOM   2596 O OE1 . GLU B 2 44  ? 24.63100  -4.74600  19.84400  1.000 42.59000 ? 44  GLU B OE1 1 
ATOM   2597 O OE2 . GLU B 2 44  ? 24.64200  -4.37500  17.67000  1.000 49.41000 ? 44  GLU B OE2 1 
ATOM   2598 N N   . ARG B 2 45  ? 25.76100  -2.33600  23.39700  1.000 21.90000 ? 45  ARG B N   1 
ATOM   2599 C CA  . ARG B 2 45  ? 26.08500  -2.06200  24.79400  1.000 23.33000 ? 45  ARG B CA  1 
ATOM   2600 C C   . ARG B 2 45  ? 27.54900  -2.38800  25.10200  1.000 20.95000 ? 45  ARG B C   1 
ATOM   2601 O O   . ARG B 2 45  ? 28.06600  -3.44300  24.72700  1.000 22.15000 ? 45  ARG B O   1 
ATOM   2602 C CB  . ARG B 2 45  ? 25.12600  -2.85400  25.67000  1.000 22.77000 ? 45  ARG B CB  1 
ATOM   2603 C CG  . ARG B 2 45  ? 25.45000  -2.80400  27.08600  1.000 33.86000 ? 45  ARG B CG  1 
ATOM   2604 C CD  . ARG B 2 45  ? 24.38800  -3.51600  27.95400  1.000 38.20000 ? 45  ARG B CD  1 
ATOM   2605 N NE  . ARG B 2 45  ? 24.78100  -3.36300  29.34400  1.000 47.01000 ? 45  ARG B NE  1 
ATOM   2606 C CZ  . ARG B 2 45  ? 25.71200  -4.10800  29.93000  1.000 52.07000 ? 45  ARG B CZ  1 
ATOM   2607 N NH1 . ARG B 2 45  ? 26.22000  -5.16900  29.32400  1.000 45.04000 ? 45  ARG B NH1 1 
ATOM   2608 N NH2 . ARG B 2 45  ? 26.15800  -3.77000  31.14200  1.000 42.08000 ? 45  ARG B NH2 1 
ATOM   2609 N N   . ILE B 2 46  ? 28.24000  -1.45500  25.73900  1.000 19.67000 ? 46  ILE B N   1 
ATOM   2610 C CA  . ILE B 2 46  ? 29.60600  -1.67400  26.19000  1.000 15.53000 ? 46  ILE B CA  1 
ATOM   2611 C C   . ILE B 2 46  ? 29.55400  -2.41900  27.52200  1.000 21.57000 ? 46  ILE B C   1 
ATOM   2612 O O   . ILE B 2 46  ? 28.85000  -2.00200  28.45100  1.000 22.06000 ? 46  ILE B O   1 
ATOM   2613 C CB  . ILE B 2 46  ? 30.32700  -0.32300  26.35500  1.000 19.07000 ? 46  ILE B CB  1 
ATOM   2614 C CG1 . ILE B 2 46  ? 30.42900  0.37500   24.99000  1.000 18.69000 ? 46  ILE B CG1 1 
ATOM   2615 C CG2 . ILE B 2 46  ? 31.73400  -0.52800  26.91800  1.000 18.32000 ? 46  ILE B CG2 1 
ATOM   2616 C CD1 . ILE B 2 46  ? 31.04900  1.81700   25.02000  1.000 15.19000 ? 46  ILE B CD1 1 
ATOM   2617 N N   . GLU B 2 47  ? 30.35100  -3.48200  27.66300  1.000 21.44000 ? 47  GLU B N   1 
ATOM   2618 C CA  . GLU B 2 47  ? 30.18000  -4.32400  28.85400  1.000 28.62000 ? 47  GLU B CA  1 
ATOM   2619 C C   . GLU B 2 47  ? 30.83300  -3.77800  30.12800  1.000 32.38000 ? 47  GLU B C   1 
ATOM   2620 O O   . GLU B 2 47  ? 30.29300  -3.94400  31.22700  1.000 36.12000 ? 47  GLU B O   1 
ATOM   2621 C CB  . GLU B 2 47  ? 30.70400  -5.74200  28.59900  1.000 32.18000 ? 47  GLU B CB  1 
ATOM   2622 C CG  . GLU B 2 47  ? 29.79700  -6.53100  27.72300  1.000 33.49000 ? 47  GLU B CG  1 
ATOM   2623 C CD  . GLU B 2 47  ? 28.43900  -6.85800  28.38300  1.000 50.95000 ? 47  GLU B CD  1 
ATOM   2624 O OE1 . GLU B 2 47  ? 28.28200  -6.74300  29.63500  1.000 55.98000 ? 47  GLU B OE1 1 
ATOM   2625 O OE2 . GLU B 2 47  ? 27.50400  -7.23300  27.62900  1.000 62.00000 ? 47  GLU B OE2 1 
ATOM   2626 N N   . LYS B 2 48  ? 32.01700  -3.21300  30.08700  1.000 22.87000 ? 48  LYS B N   1 
ATOM   2627 C CA  . LYS B 2 48  ? 32.62000  -3.03700  31.41400  1.000 39.64000 ? 48  LYS B CA  1 
ATOM   2628 C C   . LYS B 2 48  ? 32.41200  -1.64600  32.02700  1.000 37.80000 ? 48  LYS B C   1 
ATOM   2629 O O   . LYS B 2 48  ? 33.35600  -1.04300  32.54400  1.000 59.52000 ? 48  LYS B O   1 
ATOM   2630 C CB  . LYS B 2 48  ? 34.09100  -3.41200  31.37000  1.000 39.98000 ? 48  LYS B CB  1 
ATOM   2631 C CG  . LYS B 2 48  ? 34.28600  -4.84400  30.95800  0.000 50.62000 ? 48  LYS B CG  1 
ATOM   2632 C CD  . LYS B 2 48  ? 33.42500  -5.77600  31.86100  0.000 46.80000 ? 48  LYS B CD  1 
ATOM   2633 C CE  . LYS B 2 48  ? 34.31800  -6.87500  32.47500  0.000 47.04000 ? 48  LYS B CE  1 
ATOM   2634 N NZ  . LYS B 2 48  ? 33.60400  -8.16400  32.74800  0.000 62.54000 ? 48  LYS B NZ  1 
ATOM   2635 N N   . VAL B 2 49  ? 31.18500  -1.12400  32.03700  1.000 23.74000 ? 49  VAL B N   1 
ATOM   2636 C CA  . VAL B 2 49  ? 30.97500  0.24000   32.50000  1.000 18.82000 ? 49  VAL B CA  1 
ATOM   2637 C C   . VAL B 2 49  ? 30.91000  0.30200   34.01900  1.000 21.97000 ? 49  VAL B C   1 
ATOM   2638 O O   . VAL B 2 49  ? 30.17300  -0.45600  34.64800  1.000 18.35000 ? 49  VAL B O   1 
ATOM   2639 C CB  . VAL B 2 49  ? 29.71600  0.81400   31.86200  1.000 18.76000 ? 49  VAL B CB  1 
ATOM   2640 C CG1 . VAL B 2 49  ? 29.58400  2.26800   32.18000  1.000 15.94000 ? 49  VAL B CG1 1 
ATOM   2641 C CG2 . VAL B 2 49  ? 29.90500  0.72000   30.33900  1.000 15.99000 ? 49  VAL B CG2 1 
ATOM   2642 N N   . GLU B 2 50  ? 31.63000  1.24500   34.60200  1.000 16.75000 ? 50  GLU B N   1 
ATOM   2643 C CA  . GLU B 2 50  ? 31.57300  1.51800   36.03400  1.000 19.73000 ? 50  GLU B CA  1 
ATOM   2644 C C   . GLU B 2 50  ? 30.68700  2.72100   36.33900  1.000 18.62000 ? 50  GLU B C   1 
ATOM   2645 O O   . GLU B 2 50  ? 30.29600  3.47200   35.47400  1.000 16.36000 ? 50  GLU B O   1 
ATOM   2646 C CB  . GLU B 2 50  ? 32.96900  1.76000   36.58100  1.000 20.85000 ? 50  GLU B CB  1 
ATOM   2647 C CG  . GLU B 2 50  ? 33.89800  0.87400   35.93900  1.000 36.88000 ? 50  GLU B CG  1 
ATOM   2648 C CD  . GLU B 2 50  ? 34.92600  0.45800   36.88700  1.000 47.43000 ? 50  GLU B CD  1 
ATOM   2649 O OE1 . GLU B 2 50  ? 35.81000  1.28800   37.22300  1.000 52.31000 ? 50  GLU B OE1 1 
ATOM   2650 O OE2 . GLU B 2 50  ? 34.80800  -0.70800  37.31600  1.000 55.29000 ? 50  GLU B OE2 1 
ATOM   2651 N N   . HIS B 2 51  ? 30.34100  2.88600   37.60100  1.000 16.85000 ? 51  HIS B N   1 
ATOM   2652 C CA  . HIS B 2 51  ? 29.57800  4.06800   37.94800  1.000 15.19000 ? 51  HIS B CA  1 
ATOM   2653 C C   . HIS B 2 51  ? 29.98800  4.54300   39.33000  1.000 17.80000 ? 51  HIS B C   1 
ATOM   2654 O O   . HIS B 2 51  ? 30.55000  3.79200   40.13900  1.000 16.68000 ? 51  HIS B O   1 
ATOM   2655 C CB  . HIS B 2 51  ? 28.06300  3.83600   37.80200  1.000 15.56000 ? 51  HIS B CB  1 
ATOM   2656 C CG  . HIS B 2 51  ? 27.48900  2.78800   38.70600  1.000 23.03000 ? 51  HIS B CG  1 
ATOM   2657 N ND1 . HIS B 2 51  ? 27.27900  2.98400   40.05400  1.000 27.85000 ? 51  HIS B ND1 1 
ATOM   2658 C CD2 . HIS B 2 51  ? 26.99600  1.55000   38.42100  1.000 22.58000 ? 51  HIS B CD2 1 
ATOM   2659 C CE1 . HIS B 2 51  ? 26.75900  1.88300   40.57900  1.000 31.77000 ? 51  HIS B CE1 1 
ATOM   2660 N NE2 . HIS B 2 51  ? 26.56400  1.00500   39.60700  1.000 36.57000 ? 51  HIS B NE2 1 
ATOM   2661 N N   . SER B 2 52  ? 29.74900  5.82200   39.55800  1.000 15.28000 ? 52  SER B N   1 
ATOM   2662 C CA  . SER B 2 52  ? 30.08500  6.41200   40.84500  1.000 14.01000 ? 52  SER B CA  1 
ATOM   2663 C C   . SER B 2 52  ? 29.08700  5.89800   41.89100  1.000 15.25000 ? 52  SER B C   1 
ATOM   2664 O O   . SER B 2 52  ? 28.15800  5.13200   41.59100  1.000 13.15000 ? 52  SER B O   1 
ATOM   2665 C CB  . SER B 2 52  ? 30.05200  7.94100   40.74600  1.000 14.46000 ? 52  SER B CB  1 
ATOM   2666 O OG  . SER B 2 52  ? 28.74000  8.34000   40.37200  1.000 13.85000 ? 52  SER B OG  1 
ATOM   2667 N N   . ASP B 2 53  ? 29.35200  6.23600   43.14400  1.000 9.80000  ? 53  ASP B N   1 
ATOM   2668 C CA  . ASP B 2 53  ? 28.49300  5.81400   44.24500  1.000 13.71000 ? 53  ASP B CA  1 
ATOM   2669 C C   . ASP B 2 53  ? 27.33000  6.77600   44.31500  1.000 11.34000 ? 53  ASP B C   1 
ATOM   2670 O O   . ASP B 2 53  ? 27.55200  7.99300   44.34500  1.000 13.74000 ? 53  ASP B O   1 
ATOM   2671 C CB  . ASP B 2 53  ? 29.26300  5.87900   45.58700  1.000 15.51000 ? 53  ASP B CB  1 
ATOM   2672 C CG  . ASP B 2 53  ? 30.52700  5.02200   45.57000  1.000 17.42000 ? 53  ASP B CG  1 
ATOM   2673 O OD1 . ASP B 2 53  ? 30.36100  3.81200   45.35700  1.000 17.26000 ? 53  ASP B OD1 1 
ATOM   2674 O OD2 . ASP B 2 53  ? 31.61500  5.57100   45.75500  1.000 16.40000 ? 53  ASP B OD2 1 
ATOM   2675 N N   . LEU B 2 54  ? 26.12600  6.23100   44.41700  1.000 10.70000 ? 54  LEU B N   1 
ATOM   2676 C CA  . LEU B 2 54  ? 24.91100  7.02900   44.46800  1.000 10.64000 ? 54  LEU B CA  1 
ATOM   2677 C C   . LEU B 2 54  ? 24.99300  8.12300   45.53100  1.000 16.05000 ? 54  LEU B C   1 
ATOM   2678 O O   . LEU B 2 54  ? 25.23500  7.85000   46.71800  1.000 13.25000 ? 54  LEU B O   1 
ATOM   2679 C CB  . LEU B 2 54  ? 23.73300  6.11400   44.81200  1.000 11.35000 ? 54  LEU B CB  1 
ATOM   2680 C CG  . LEU B 2 54  ? 22.34700  6.75200   44.70000  1.000 13.07000 ? 54  LEU B CG  1 
ATOM   2681 C CD1 . LEU B 2 54  ? 22.02300  7.18000   43.19800  1.000 11.10000 ? 54  LEU B CD1 1 
ATOM   2682 C CD2 . LEU B 2 54  ? 21.26300  5.78700   45.21700  1.000 12.68000 ? 54  LEU B CD2 1 
ATOM   2683 N N   . SER B 2 55  ? 24.66200  9.35100   45.12600  1.000 10.81000 ? 55  SER B N   1 
ATOM   2684 C CA  . SER B 2 55  ? 24.65000  10.50400  46.01400  1.000 11.14000 ? 55  SER B CA  1 
ATOM   2685 C C   . SER B 2 55  ? 23.53000  11.42600  45.55000  1.000 11.29000 ? 55  SER B C   1 
ATOM   2686 O O   . SER B 2 55  ? 22.85400  11.14800  44.54900  1.000 10.95000 ? 55  SER B O   1 
ATOM   2687 C CB  . SER B 2 55  ? 26.00600  11.21200  46.03000  1.000 11.92000 ? 55  SER B CB  1 
ATOM   2688 O OG  . SER B 2 55  ? 25.95200  12.19500  47.05300  1.000 17.09000 ? 55  SER B OG  1 
ATOM   2689 N N   . PHE B 2 56  ? 23.26800  12.48400  46.29400  1.000 10.75000 ? 56  PHE B N   1 
ATOM   2690 C CA  . PHE B 2 56  ? 22.10600  13.31300  45.92500  1.000 11.36000 ? 56  PHE B CA  1 
ATOM   2691 C C   . PHE B 2 56  ? 22.34100  14.74800  46.36600  1.000 13.53000 ? 56  PHE B C   1 
ATOM   2692 O O   . PHE B 2 56  ? 23.25200  15.03900  47.13900  1.000 12.28000 ? 56  PHE B O   1 
ATOM   2693 C CB  . PHE B 2 56  ? 20.79300  12.75800  46.49800  1.000 10.27000 ? 56  PHE B CB  1 
ATOM   2694 C CG  . PHE B 2 56  ? 20.78900  12.55000  48.04800  1.000 12.12000 ? 56  PHE B CG  1 
ATOM   2695 C CD1 . PHE B 2 56  ? 20.46600  13.58100  48.90400  1.000 13.41000 ? 56  PHE B CD1 1 
ATOM   2696 C CD2 . PHE B 2 56  ? 21.10100  11.28800  48.58300  1.000 8.63000  ? 56  PHE B CD2 1 
ATOM   2697 C CE1 . PHE B 2 56  ? 20.44400  13.37600  50.32000  1.000 10.20000 ? 56  PHE B CE1 1 
ATOM   2698 C CE2 . PHE B 2 56  ? 21.05600  11.07100  49.97300  1.000 11.09000 ? 56  PHE B CE2 1 
ATOM   2699 C CZ  . PHE B 2 56  ? 20.72600  12.13900  50.84900  1.000 7.81000  ? 56  PHE B CZ  1 
ATOM   2700 N N   . SER B 2 57  ? 21.52900  15.63300  45.83700  1.000 13.94000 ? 57  SER B N   1 
ATOM   2701 C CA  . SER B 2 57  ? 21.65800  17.06000  46.00300  1.000 15.79000 ? 57  SER B CA  1 
ATOM   2702 C C   . SER B 2 57  ? 20.72900  17.56200  47.10700  1.000 17.94000 ? 57  SER B C   1 
ATOM   2703 O O   . SER B 2 57  ? 19.95900  16.80100  47.69200  1.000 14.68000 ? 57  SER B O   1 
ATOM   2704 C CB  . SER B 2 57  ? 21.38900  17.75900  44.66300  1.000 19.17000 ? 57  SER B CB  1 
ATOM   2705 O OG  . SER B 2 57  ? 22.28200  17.19800  43.64100  1.000 20.36000 ? 57  SER B OG  1 
ATOM   2706 N N   . GLY B 2 58  ? 20.84200  18.87900  47.38900  1.000 13.24000 ? 58  GLY B N   1 
ATOM   2707 C CA  . GLY B 2 58  ? 20.04200  19.54100  48.41100  1.000 16.39000 ? 58  GLY B CA  1 
ATOM   2708 C C   . GLY B 2 58  ? 18.55500  19.30300  48.23000  1.000 17.42000 ? 58  GLY B C   1 
ATOM   2709 O O   . GLY B 2 58  ? 17.80900  19.27300  49.20400  1.000 17.23000 ? 58  GLY B O   1 
ATOM   2710 N N   . ASP B 2 59  ? 18.10200  19.08300  47.00200  1.000 14.17000 ? 59  ASP B N   1 
ATOM   2711 C CA  . ASP B 2 59  ? 16.66100  18.85000  46.77200  1.000 13.98000 ? 59  ASP B CA  1 
ATOM   2712 C C   . ASP B 2 59  ? 16.29500  17.36000  46.75900  1.000 17.54000 ? 59  ASP B C   1 
ATOM   2713 O O   . ASP B 2 59  ? 15.19700  16.98800  46.31400  1.000 14.02000 ? 59  ASP B O   1 
ATOM   2714 C CB  . ASP B 2 59  ? 16.22300  19.51600  45.45900  1.000 19.57000 ? 59  ASP B CB  1 
ATOM   2715 C CG  . ASP B 2 59  ? 16.83800  18.86100  44.19300  1.000 21.77000 ? 59  ASP B CG  1 
ATOM   2716 O OD1 . ASP B 2 59  ? 17.63300  17.85500  44.29400  1.000 18.61000 ? 59  ASP B OD1 1 
ATOM   2717 O OD2 . ASP B 2 59  ? 16.51900  19.35100  43.05600  1.000 20.61000 ? 59  ASP B OD2 1 
ATOM   2718 N N   . TRP B 2 60  ? 17.19200  16.49900  47.25800  1.000 15.84000 ? 60  TRP B N   1 
ATOM   2719 C CA  . TRP B 2 60  ? 17.01100  15.06200  47.35500  1.000 12.21000 ? 60  TRP B CA  1 
ATOM   2720 C C   . TRP B 2 60  ? 17.19600  14.36000  46.00500  1.000 10.31000 ? 60  TRP B C   1 
ATOM   2721 O O   . TRP B 2 60  ? 17.18600  13.14600  45.98800  1.000 13.77000 ? 60  TRP B O   1 
ATOM   2722 C CB  . TRP B 2 60  ? 15.65200  14.64600  47.93600  1.000 11.90000 ? 60  TRP B CB  1 
ATOM   2723 C CG  . TRP B 2 60  ? 15.37800  15.31100  49.28200  1.000 13.04000 ? 60  TRP B CG  1 
ATOM   2724 C CD1 . TRP B 2 60  ? 14.47400  16.30600  49.55000  1.000 14.95000 ? 60  TRP B CD1 1 
ATOM   2725 C CD2 . TRP B 2 60  ? 16.08200  15.05900  50.52200  1.000 13.77000 ? 60  TRP B CD2 1 
ATOM   2726 N NE1 . TRP B 2 60  ? 14.53800  16.67200  50.90800  1.000 16.13000 ? 60  TRP B NE1 1 
ATOM   2727 C CE2 . TRP B 2 60  ? 15.52300  15.93100  51.51400  1.000 14.46000 ? 60  TRP B CE2 1 
ATOM   2728 C CE3 . TRP B 2 60  ? 17.06700  14.13800  50.89800  1.000 11.87000 ? 60  TRP B CE3 1 
ATOM   2729 C CZ2 . TRP B 2 60  ? 15.95100  15.94800  52.84100  1.000 14.77000 ? 60  TRP B CZ2 1 
ATOM   2730 C CZ3 . TRP B 2 60  ? 17.49800  14.13200  52.24500  1.000 13.56000 ? 60  TRP B CZ3 1 
ATOM   2731 C CH2 . TRP B 2 60  ? 16.91400  15.02500  53.21000  1.000 15.81000 ? 60  TRP B CH2 1 
ATOM   2732 N N   . SER B 2 61  ? 17.36100  15.06900  44.87400  1.000 12.61000 ? 61  SER B N   1 
ATOM   2733 C CA  . SER B 2 61  ? 17.50300  14.38100  43.58500  1.000 9.15000  ? 61  SER B CA  1 
ATOM   2734 C C   . SER B 2 61  ? 18.89800  13.78300  43.43900  1.000 10.60000 ? 61  SER B C   1 
ATOM   2735 O O   . SER B 2 61  ? 19.88000  14.32500  43.93200  1.000 11.90000 ? 61  SER B O   1 
ATOM   2736 C CB  . SER B 2 61  ? 17.25900  15.32800  42.36800  1.000 11.79000 ? 61  SER B CB  1 
ATOM   2737 O OG  . SER B 2 61  ? 18.26400  16.36400  42.36200  1.000 13.08000 ? 61  SER B OG  1 
ATOM   2738 N N   . PHE B 2 62  ? 18.97400  12.69900  42.70400  1.000 9.64000  ? 62  PHE B N   1 
ATOM   2739 C CA  . PHE B 2 62  ? 20.16400  11.86300  42.68500  1.000 11.66000 ? 62  PHE B CA  1 
ATOM   2740 C C   . PHE B 2 62  ? 21.06600  12.26800  41.53500  1.000 10.57000 ? 62  PHE B C   1 
ATOM   2741 O O   . PHE B 2 62  ? 20.60800  12.82200  40.54200  1.000 12.74000 ? 62  PHE B O   1 
ATOM   2742 C CB  . PHE B 2 62  ? 19.76500  10.39900  42.50300  1.000 13.08000 ? 62  PHE B CB  1 
ATOM   2743 C CG  . PHE B 2 62  ? 19.05700  9.81900   43.69400  1.000 10.06000 ? 62  PHE B CG  1 
ATOM   2744 C CD1 . PHE B 2 62  ? 19.80200  9.45300   44.83300  1.000 11.99000 ? 62  PHE B CD1 1 
ATOM   2745 C CD2 . PHE B 2 62  ? 17.70900  9.67200   43.70500  1.000 10.93000 ? 62  PHE B CD2 1 
ATOM   2746 C CE1 . PHE B 2 62  ? 19.17800  8.91800   45.93700  1.000 12.65000 ? 62  PHE B CE1 1 
ATOM   2747 C CE2 . PHE B 2 62  ? 17.05600  9.14400   44.82700  1.000 9.82000  ? 62  PHE B CE2 1 
ATOM   2748 C CZ  . PHE B 2 62  ? 17.80200  8.77000   45.94500  1.000 12.46000 ? 62  PHE B CZ  1 
ATOM   2749 N N   . TYR B 2 63  ? 22.33600  11.86300  41.62200  1.000 11.12000 ? 63  TYR B N   1 
ATOM   2750 C CA  . TYR B 2 63  ? 23.26200  11.99900  40.48000  1.000 9.06000  ? 63  TYR B CA  1 
ATOM   2751 C C   . TYR B 2 63  ? 24.27700  10.85300  40.47700  1.000 10.34000 ? 63  TYR B C   1 
ATOM   2752 O O   . TYR B 2 63  ? 24.65700  10.34500  41.53500  1.000 12.64000 ? 63  TYR B O   1 
ATOM   2753 C CB  . TYR B 2 63  ? 24.01100  13.36600  40.48400  1.000 10.66000 ? 63  TYR B CB  1 
ATOM   2754 C CG  . TYR B 2 63  ? 24.84500  13.63200  41.74800  1.000 12.74000 ? 63  TYR B CG  1 
ATOM   2755 C CD1 . TYR B 2 63  ? 26.17600  13.21600  41.84100  1.000 15.93000 ? 63  TYR B CD1 1 
ATOM   2756 C CD2 . TYR B 2 63  ? 24.28900  14.30000  42.83900  1.000 14.06000 ? 63  TYR B CD2 1 
ATOM   2757 C CE1 . TYR B 2 63  ? 26.91400  13.42500  42.99000  1.000 15.09000 ? 63  TYR B CE1 1 
ATOM   2758 C CE2 . TYR B 2 63  ? 25.01000  14.53500  43.99300  1.000 15.71000 ? 63  TYR B CE2 1 
ATOM   2759 C CZ  . TYR B 2 63  ? 26.33400  14.10100  44.05500  1.000 19.35000 ? 63  TYR B CZ  1 
ATOM   2760 O OH  . TYR B 2 63  ? 27.05200  14.26900  45.20200  1.000 22.07000 ? 63  TYR B OH  1 
ATOM   2761 N N   . LEU B 2 64  ? 24.68000  10.43200  39.26700  1.000 9.60000  ? 64  LEU B N   1 
ATOM   2762 C CA  . LEU B 2 64  ? 25.59000  9.29900   39.06500  1.000 9.60000  ? 64  LEU B CA  1 
ATOM   2763 C C   . LEU B 2 64  ? 26.42800  9.61900   37.83900  1.000 13.94000 ? 64  LEU B C   1 
ATOM   2764 O O   . LEU B 2 64  ? 25.90100  10.14400  36.84700  1.000 11.76000 ? 64  LEU B O   1 
ATOM   2765 C CB  . LEU B 2 64  ? 24.83000  7.96700   38.79600  1.000 11.62000 ? 64  LEU B CB  1 
ATOM   2766 C CG  . LEU B 2 64  ? 24.09300  7.25600   39.94700  1.000 12.62000 ? 64  LEU B CG  1 
ATOM   2767 C CD1 . LEU B 2 64  ? 23.18200  6.18200   39.37600  1.000 14.22000 ? 64  LEU B CD1 1 
ATOM   2768 C CD2 . LEU B 2 64  ? 25.20900  6.65600   40.87300  1.000 12.52000 ? 64  LEU B CD2 1 
ATOM   2769 N N   . LEU B 2 65  ? 27.69300  9.18900   37.86700  1.000 11.33000 ? 65  LEU B N   1 
ATOM   2770 C CA  . LEU B 2 65  ? 28.53600  9.25100   36.67300  1.000 9.96000  ? 65  LEU B CA  1 
ATOM   2771 C C   . LEU B 2 65  ? 28.83200  7.82800   36.25000  1.000 12.77000 ? 65  LEU B C   1 
ATOM   2772 O O   . LEU B 2 65  ? 29.30700  7.04000   37.07200  1.000 12.26000 ? 65  LEU B O   1 
ATOM   2773 C CB  . LEU B 2 65  ? 29.84300  9.97100   36.98500  1.000 10.97000 ? 65  LEU B CB  1 
ATOM   2774 C CG  . LEU B 2 65  ? 30.80200  10.10500  35.79300  1.000 14.74000 ? 65  LEU B CG  1 
ATOM   2775 C CD1 . LEU B 2 65  ? 30.20000  11.01000  34.69100  1.000 11.73000 ? 65  LEU B CD1 1 
ATOM   2776 C CD2 . LEU B 2 65  ? 32.27100  10.66400  36.27100  1.000 13.16000 ? 65  LEU B CD2 1 
ATOM   2777 N N   . TYR B 2 66  ? 28.51600  7.49200   34.99500  1.000 11.27000 ? 66  TYR B N   1 
ATOM   2778 C CA  . TYR B 2 66  ? 28.85100  6.20400   34.42900  1.000 13.00000 ? 66  TYR B CA  1 
ATOM   2779 C C   . TYR B 2 66  ? 30.02500  6.42800   33.50800  1.000 14.69000 ? 66  TYR B C   1 
ATOM   2780 O O   . TYR B 2 66  ? 30.03100  7.42400   32.77700  1.000 11.91000 ? 66  TYR B O   1 
ATOM   2781 C CB  . TYR B 2 66  ? 27.68400  5.64500   33.60600  1.000 11.01000 ? 66  TYR B CB  1 
ATOM   2782 C CG  . TYR B 2 66  ? 26.56700  5.07500   34.46300  1.000 13.71000 ? 66  TYR B CG  1 
ATOM   2783 C CD1 . TYR B 2 66  ? 25.73600  5.91800   35.15900  1.000 10.68000 ? 66  TYR B CD1 1 
ATOM   2784 C CD2 . TYR B 2 66  ? 26.41300  3.67700   34.62500  1.000 16.90000 ? 66  TYR B CD2 1 
ATOM   2785 C CE1 . TYR B 2 66  ? 24.72800  5.42000   35.97500  1.000 12.36000 ? 66  TYR B CE1 1 
ATOM   2786 C CE2 . TYR B 2 66  ? 25.42900  3.15800   35.45700  1.000 15.21000 ? 66  TYR B CE2 1 
ATOM   2787 C CZ  . TYR B 2 66  ? 24.60200  4.04500   36.11600  1.000 17.92000 ? 66  TYR B CZ  1 
ATOM   2788 O OH  . TYR B 2 66  ? 23.59500  3.55200   36.88600  1.000 19.23000 ? 66  TYR B OH  1 
ATOM   2789 N N   . TYR B 2 67  ? 31.00200  5.51500   33.52200  1.000 14.81000 ? 67  TYR B N   1 
ATOM   2790 C CA  . TYR B 2 67  ? 32.18600  5.80700   32.69600  1.000 12.01000 ? 67  TYR B CA  1 
ATOM   2791 C C   . TYR B 2 67  ? 32.90700  4.53900   32.27500  1.000 15.47000 ? 67  TYR B C   1 
ATOM   2792 O O   . TYR B 2 67  ? 32.79500  3.49900   32.91000  1.000 14.00000 ? 67  TYR B O   1 
ATOM   2793 C CB  . TYR B 2 67  ? 33.16700  6.72300   33.41000  1.000 12.73000 ? 67  TYR B CB  1 
ATOM   2794 C CG  . TYR B 2 67  ? 33.58100  6.16500   34.72300  1.000 16.10000 ? 67  TYR B CG  1 
ATOM   2795 C CD1 . TYR B 2 67  ? 32.74700  6.29500   35.84400  1.000 15.97000 ? 67  TYR B CD1 1 
ATOM   2796 C CD2 . TYR B 2 67  ? 34.78400  5.48800   34.87300  1.000 19.49000 ? 67  TYR B CD2 1 
ATOM   2797 C CE1 . TYR B 2 67  ? 33.12500  5.77800   37.07900  1.000 18.45000 ? 67  TYR B CE1 1 
ATOM   2798 C CE2 . TYR B 2 67  ? 35.14600  4.95400   36.08800  1.000 23.08000 ? 67  TYR B CE2 1 
ATOM   2799 C CZ  . TYR B 2 67  ? 34.28800  5.10600   37.18200  1.000 27.64000 ? 67  TYR B CZ  1 
ATOM   2800 O OH  . TYR B 2 67  ? 34.58500  4.62700   38.40400  1.000 29.24000 ? 67  TYR B OH  1 
ATOM   2801 N N   . THR B 2 68  ? 33.67100  4.64900   31.18000  1.000 13.50000 ? 68  THR B N   1 
ATOM   2802 C CA  . THR B 2 68  ? 34.40900  3.49100   30.69600  1.000 18.43000 ? 68  THR B CA  1 
ATOM   2803 C C   . THR B 2 68  ? 35.65600  3.99600   29.97300  1.000 19.55000 ? 68  THR B C   1 
ATOM   2804 O O   . THR B 2 68  ? 35.64900  5.06700   29.35800  1.000 14.26000 ? 68  THR B O   1 
ATOM   2805 C CB  . THR B 2 68  ? 33.53000  2.61600   29.76100  1.000 19.80000 ? 68  THR B CB  1 
ATOM   2806 O OG1 . THR B 2 68  ? 34.23200  1.41400   29.43400  1.000 23.97000 ? 68  THR B OG1 1 
ATOM   2807 C CG2 . THR B 2 68  ? 33.23100  3.31500   28.43500  1.000 17.55000 ? 68  THR B CG2 1 
ATOM   2808 N N   . GLU B 2 69  ? 36.74400  3.23800   30.07900  1.000 16.99000 ? 69  GLU B N   1 
ATOM   2809 C CA  . GLU B 2 69  ? 37.89700  3.54500   29.24300  1.000 16.67000 ? 69  GLU B CA  1 
ATOM   2810 C C   . GLU B 2 69  ? 37.52700  3.32800   27.78500  1.000 17.34000 ? 69  GLU B C   1 
ATOM   2811 O O   . GLU B 2 69  ? 36.85600  2.35200   27.45700  1.000 22.35000 ? 69  GLU B O   1 
ATOM   2812 C CB  . GLU B 2 69  ? 39.06300  2.65100   29.66600  1.000 25.58000 ? 69  GLU B CB  1 
ATOM   2813 C CG  . GLU B 2 69  ? 40.40800  3.16600   29.32000  1.000 32.76000 ? 69  GLU B CG  1 
ATOM   2814 C CD  . GLU B 2 69  ? 41.50000  2.64500   30.30000  1.000 47.12000 ? 69  GLU B CD  1 
ATOM   2815 O OE1 . GLU B 2 69  ? 41.51900  1.42100   30.56600  1.000 55.52000 ? 69  GLU B OE1 1 
ATOM   2816 O OE2 . GLU B 2 69  ? 42.30800  3.46000   30.80900  1.000 55.11000 ? 69  GLU B OE2 1 
ATOM   2817 N N   . PHE B 2 70  ? 37.92700  4.26300   26.89400  1.000 15.92000 ? 70  PHE B N   1 
ATOM   2818 C CA  . PHE B 2 70  ? 37.71500  4.07600   25.46000  1.000 16.17000 ? 70  PHE B CA  1 
ATOM   2819 C C   . PHE B 2 70  ? 38.80800  4.80500   24.68600  1.000 23.01000 ? 70  PHE B C   1 
ATOM   2820 O O   . PHE B 2 70  ? 39.48000  5.69300   25.22300  1.000 15.49000 ? 70  PHE B O   1 
ATOM   2821 C CB  . PHE B 2 70  ? 36.33700  4.52200   25.00200  1.000 17.23000 ? 70  PHE B CB  1 
ATOM   2822 C CG  . PHE B 2 70  ? 36.18100  6.00300   24.69400  1.000 16.00000 ? 70  PHE B CG  1 
ATOM   2823 C CD1 . PHE B 2 70  ? 36.61500  6.98800   25.58000  1.000 12.90000 ? 70  PHE B CD1 1 
ATOM   2824 C CD2 . PHE B 2 70  ? 35.50500  6.40000   23.56500  1.000 13.84000 ? 70  PHE B CD2 1 
ATOM   2825 C CE1 . PHE B 2 70  ? 36.42500  8.30100   25.29300  1.000 13.66000 ? 70  PHE B CE1 1 
ATOM   2826 C CE2 . PHE B 2 70  ? 35.27100  7.73300   23.28400  1.000 16.30000 ? 70  PHE B CE2 1 
ATOM   2827 C CZ  . PHE B 2 70  ? 35.71000  8.69700   24.15100  1.000 13.62000 ? 70  PHE B CZ  1 
ATOM   2828 N N   . THR B 2 71  ? 39.02400  4.35200   23.44600  1.000 17.07000 ? 71  THR B N   1 
ATOM   2829 C CA  . THR B 2 71  ? 39.97200  4.98600   22.52700  1.000 17.48000 ? 71  THR B CA  1 
ATOM   2830 C C   . THR B 2 71  ? 39.20600  5.50000   21.32700  1.000 20.17000 ? 71  THR B C   1 
ATOM   2831 O O   . THR B 2 71  ? 38.81800  4.70600   20.44400  1.000 20.60000 ? 71  THR B O   1 
ATOM   2832 C CB  . THR B 2 71  ? 41.04100  3.97600   22.12000  1.000 20.54000 ? 71  THR B CB  1 
ATOM   2833 O OG1 . THR B 2 71  ? 41.76200  3.62300   23.29500  1.000 22.44000 ? 71  THR B OG1 1 
ATOM   2834 C CG2 . THR B 2 71  ? 42.02500  4.58500   21.12200  1.000 16.77000 ? 71  THR B CG2 1 
ATOM   2835 N N   . PRO B 2 72  ? 38.87700  6.79400   21.28300  1.000 19.06000 ? 72  PRO B N   1 
ATOM   2836 C CA  . PRO B 2 72  ? 38.04600  7.29800   20.18100  1.000 20.33000 ? 72  PRO B CA  1 
ATOM   2837 C C   . PRO B 2 72  ? 38.77600  7.14900   18.84700  1.000 17.58000 ? 72  PRO B C   1 
ATOM   2838 O O   . PRO B 2 72  ? 40.00600  7.10400   18.80600  1.000 17.02000 ? 72  PRO B O   1 
ATOM   2839 C CB  . PRO B 2 72  ? 37.82400  8.78400   20.52900  1.000 17.73000 ? 72  PRO B CB  1 
ATOM   2840 C CG  . PRO B 2 72  ? 38.94200  9.10300   21.48100  1.000 16.18000 ? 72  PRO B CG  1 
ATOM   2841 C CD  . PRO B 2 72  ? 39.28100  7.85600   22.22800  1.000 18.00000 ? 72  PRO B CD  1 
ATOM   2842 N N   . THR B 2 73  ? 37.99000  7.03700   17.77800  1.000 17.10000 ? 73  THR B N   1 
ATOM   2843 C CA  . THR B 2 73  ? 38.45100  6.97200   16.39700  1.000 22.36000 ? 73  THR B CA  1 
ATOM   2844 C C   . THR B 2 73  ? 37.59700  7.90500   15.56700  1.000 20.97000 ? 73  THR B C   1 
ATOM   2845 O O   . THR B 2 73  ? 36.58200  8.42600   16.02400  1.000 17.58000 ? 73  THR B O   1 
ATOM   2846 C CB  . THR B 2 73  ? 38.35500  5.56000   15.80100  1.000 22.48000 ? 73  THR B CB  1 
ATOM   2847 O OG1 . THR B 2 73  ? 36.98200  5.19200   15.76000  1.000 18.89000 ? 73  THR B OG1 1 
ATOM   2848 C CG2 . THR B 2 73  ? 39.13800  4.51800   16.61200  1.000 19.29000 ? 73  THR B CG2 1 
ATOM   2849 N N   . GLU B 2 74  ? 37.98800  8.07400   14.29900  1.000 17.98000 ? 74  GLU B N   1 
ATOM   2850 C CA  . GLU B 2 74  ? 37.19300  8.86800   13.36600  1.000 17.34000 ? 74  GLU B CA  1 
ATOM   2851 C C   . GLU B 2 74  ? 35.75700  8.34500   13.25000  1.000 24.43000 ? 74  GLU B C   1 
ATOM   2852 O O   . GLU B 2 74  ? 34.80300  9.11800   13.28600  1.000 19.30000 ? 74  GLU B O   1 
ATOM   2853 C CB  . GLU B 2 74  ? 37.86600  8.87800   11.97500  1.000 22.52000 ? 74  GLU B CB  1 
ATOM   2854 C CG  . GLU B 2 74  ? 37.00200  9.63900   10.92600  1.000 19.97000 ? 74  GLU B CG  1 
ATOM   2855 C CD  . GLU B 2 74  ? 37.46300  9.38700   9.47700   1.000 22.42000 ? 74  GLU B CD  1 
ATOM   2856 O OE1 . GLU B 2 74  ? 38.36400  8.55100   9.25400   1.000 31.63000 ? 74  GLU B OE1 1 
ATOM   2857 O OE2 . GLU B 2 74  ? 36.95100  10.05900  8.59500   1.000 35.23000 ? 74  GLU B OE2 1 
ATOM   2858 N N   . LYS B 2 75  ? 35.58700  7.04000   13.06800  1.000 21.92000 ? 75  LYS B N   1 
ATOM   2859 C CA  . LYS B 2 75  ? 34.28200  6.52500   12.64600  1.000 19.00000 ? 75  LYS B CA  1 
ATOM   2860 C C   . LYS B 2 75  ? 33.44700  5.81400   13.72700  1.000 18.93000 ? 75  LYS B C   1 
ATOM   2861 O O   . LYS B 2 75  ? 32.23500  5.66100   13.52300  1.000 19.83000 ? 75  LYS B O   1 
ATOM   2862 C CB  . LYS B 2 75  ? 34.47000  5.54400   11.47800  1.000 30.07000 ? 75  LYS B CB  1 
ATOM   2863 C CG  . LYS B 2 75  ? 35.02500  6.16900   10.21100  1.000 30.85000 ? 75  LYS B CG  1 
ATOM   2864 C CD  . LYS B 2 75  ? 33.94200  6.85200   9.39800   1.000 37.15000 ? 75  LYS B CD  1 
ATOM   2865 C CE  . LYS B 2 75  ? 34.51800  7.22100   8.05500   1.000 43.12000 ? 75  LYS B CE  1 
ATOM   2866 N NZ  . LYS B 2 75  ? 35.32900  6.04500   7.61000   1.000 45.51000 ? 75  LYS B NZ  1 
ATOM   2867 N N   . ASP B 2 76  ? 34.02000  5.40000   14.85300  1.000 16.45000 ? 76  ASP B N   1 
ATOM   2868 C CA  . ASP B 2 76  ? 33.18900  4.75800   15.88200  1.000 17.68000 ? 76  ASP B CA  1 
ATOM   2869 C C   . ASP B 2 76  ? 32.21500  5.76200   16.51200  1.000 21.83000 ? 76  ASP B C   1 
ATOM   2870 O O   . ASP B 2 76  ? 32.62500  6.84200   16.92300  1.000 23.03000 ? 76  ASP B O   1 
ATOM   2871 C CB  . ASP B 2 76  ? 34.08600  4.15800   16.96400  1.000 15.98000 ? 76  ASP B CB  1 
ATOM   2872 C CG  . ASP B 2 76  ? 34.80900  2.90000   16.48100  1.000 18.74000 ? 76  ASP B CG  1 
ATOM   2873 O OD1 . ASP B 2 76  ? 34.17400  2.06900   15.80900  1.000 20.05000 ? 76  ASP B OD1 1 
ATOM   2874 O OD2 . ASP B 2 76  ? 35.99000  2.73200   16.80400  1.000 24.68000 ? 76  ASP B OD2 1 
ATOM   2875 N N   . GLU B 2 77  ? 30.93500  5.39100   16.66000  1.000 14.43000 ? 77  GLU B N   1 
ATOM   2876 C CA  . GLU B 2 77  ? 29.89700  6.28500   17.21700  1.000 16.81000 ? 77  GLU B CA  1 
ATOM   2877 C C   . GLU B 2 77  ? 29.54300  5.82300   18.63200  1.000 17.69000 ? 77  GLU B C   1 
ATOM   2878 O O   . GLU B 2 77  ? 29.29000  4.62500   18.86000  1.000 17.48000 ? 77  GLU B O   1 
ATOM   2879 C CB  . GLU B 2 77  ? 28.61800  6.26500   16.36500  1.000 23.34000 ? 77  GLU B CB  1 
ATOM   2880 C CG  . GLU B 2 77  ? 28.88000  6.66800   14.93400  1.000 32.52000 ? 77  GLU B CG  1 
ATOM   2881 C CD  . GLU B 2 77  ? 27.60700  6.68700   14.13200  1.000 51.78000 ? 77  GLU B CD  1 
ATOM   2882 O OE1 . GLU B 2 77  ? 26.83500  5.71300   14.23000  1.000 59.15000 ? 77  GLU B OE1 1 
ATOM   2883 O OE2 . GLU B 2 77  ? 27.40100  7.66000   13.37500  1.000 70.57000 ? 77  GLU B OE2 1 
ATOM   2884 N N   . TYR B 2 78  ? 29.57500  6.75100   19.57200  1.000 15.44000 ? 78  TYR B N   1 
ATOM   2885 C CA  . TYR B 2 78  ? 29.33400  6.45700   20.97100  1.000 15.39000 ? 78  TYR B CA  1 
ATOM   2886 C C   . TYR B 2 78  ? 28.07200  7.19600   21.39500  1.000 14.14000 ? 78  TYR B C   1 
ATOM   2887 O O   . TYR B 2 78  ? 27.75300  8.28000   20.87800  1.000 14.36000 ? 78  TYR B O   1 
ATOM   2888 C CB  . TYR B 2 78  ? 30.55000  6.84700   21.87700  1.000 9.99000  ? 78  TYR B CB  1 
ATOM   2889 C CG  . TYR B 2 78  ? 31.73500  5.92900   21.65600  1.000 16.23000 ? 78  TYR B CG  1 
ATOM   2890 C CD1 . TYR B 2 78  ? 31.81900  4.71600   22.32900  1.000 13.58000 ? 78  TYR B CD1 1 
ATOM   2891 C CD2 . TYR B 2 78  ? 32.73000  6.24500   20.68900  1.000 15.73000 ? 78  TYR B CD2 1 
ATOM   2892 C CE1 . TYR B 2 78  ? 32.91800  3.84100   22.12100  1.000 14.85000 ? 78  TYR B CE1 1 
ATOM   2893 C CE2 . TYR B 2 78  ? 33.79000  5.39500   20.45100  1.000 15.92000 ? 78  TYR B CE2 1 
ATOM   2894 C CZ  . TYR B 2 78  ? 33.88400  4.20800   21.19400  1.000 17.52000 ? 78  TYR B CZ  1 
ATOM   2895 O OH  . TYR B 2 78  ? 34.91900  3.38300   20.97300  1.000 18.76000 ? 78  TYR B OH  1 
ATOM   2896 N N   . ALA B 2 79  ? 27.35400  6.59900   22.33600  1.000 11.46000 ? 79  ALA B N   1 
ATOM   2897 C CA  . ALA B 2 79  ? 26.12000  7.20100   22.81800  1.000 13.62000 ? 79  ALA B CA  1 
ATOM   2898 C C   . ALA B 2 79  ? 25.85300  6.69100   24.23100  1.000 13.12000 ? 79  ALA B C   1 
ATOM   2899 O O   . ALA B 2 79  ? 26.49300  5.76200   24.69900  1.000 14.08000 ? 79  ALA B O   1 
ATOM   2900 C CB  . ALA B 2 79  ? 24.96600  6.87800   21.86900  1.000 14.89000 ? 79  ALA B CB  1 
ATOM   2901 N N   . CYS B 2 80  ? 24.91800  7.33600   24.91800  1.000 12.11000 ? 80  CYS B N   1 
ATOM   2902 C CA  . CYS B 2 80  ? 24.44400  6.88800   26.22400  1.000 14.56000 ? 80  CYS B CA  1 
ATOM   2903 C C   . CYS B 2 80  ? 22.95400  6.61500   26.08800  1.000 14.65000 ? 80  CYS B C   1 
ATOM   2904 O O   . CYS B 2 80  ? 22.26200  7.34700   25.40500  1.000 20.47000 ? 80  CYS B O   1 
ATOM   2905 C CB  . CYS B 2 80  ? 24.69800  7.98000   27.28700  1.000 14.13000 ? 80  CYS B CB  1 
ATOM   2906 S SG  . CYS B 2 80  ? 24.26700  7.49600   29.02700  1.000 27.26000 ? 80  CYS B SG  1 
ATOM   2907 N N   . ARG B 2 81  ? 22.47200  5.54100   26.67400  1.000 15.52000 ? 81  ARG B N   1 
ATOM   2908 C CA  . ARG B 2 81  ? 21.05200  5.21700   26.60000  1.000 14.76000 ? 81  ARG B CA  1 
ATOM   2909 C C   . ARG B 2 81  ? 20.54100  5.12800   28.02100  1.000 15.97000 ? 81  ARG B C   1 
ATOM   2910 O O   . ARG B 2 81  ? 21.09600  4.38600   28.82600  1.000 16.08000 ? 81  ARG B O   1 
ATOM   2911 C CB  . ARG B 2 81  ? 20.81800  3.90800   25.87200  1.000 14.19000 ? 81  ARG B CB  1 
ATOM   2912 C CG  . ARG B 2 81  ? 19.27700  3.47900   25.94700  1.000 16.28000 ? 81  ARG B CG  1 
ATOM   2913 C CD  . ARG B 2 81  ? 19.04800  2.18300   25.15900  1.000 23.03000 ? 81  ARG B CD  1 
ATOM   2914 N NE  . ARG B 2 81  ? 19.80400  1.09500   25.76000  1.000 28.09000 ? 81  ARG B NE  1 
ATOM   2915 C CZ  . ARG B 2 81  ? 20.40200  0.11000   25.10100  1.000 26.28000 ? 81  ARG B CZ  1 
ATOM   2916 N NH1 . ARG B 2 81  ? 20.35800  0.04100   23.76500  1.000 28.02000 ? 81  ARG B NH1 1 
ATOM   2917 N NH2 . ARG B 2 81  ? 21.06700  -0.82200  25.80100  1.000 30.42000 ? 81  ARG B NH2 1 
ATOM   2918 N N   . VAL B 2 82  ? 19.51900  5.90500   28.33700  1.000 13.13000 ? 82  VAL B N   1 
ATOM   2919 C CA  . VAL B 2 82  ? 19.08400  6.08900   29.71900  1.000 13.77000 ? 82  VAL B CA  1 
ATOM   2920 C C   . VAL B 2 82  ? 17.60700  5.72200   29.77600  1.000 14.43000 ? 82  VAL B C   1 
ATOM   2921 O O   . VAL B 2 82  ? 16.83100  6.22700   28.96700  1.000 17.55000 ? 82  VAL B O   1 
ATOM   2922 C CB  . VAL B 2 82  ? 19.31300  7.54700   30.15700  1.000 12.55000 ? 82  VAL B CB  1 
ATOM   2923 C CG1 . VAL B 2 82  ? 18.66400  7.81300   31.55600  1.000 10.18000 ? 82  VAL B CG1 1 
ATOM   2924 C CG2 . VAL B 2 82  ? 20.84400  7.81600   30.22400  1.000 13.40000 ? 82  VAL B CG2 1 
ATOM   2925 N N   . ASN B 2 83  ? 17.21600  4.84600   30.70000  1.000 12.73000 ? 83  ASN B N   1 
ATOM   2926 C CA  . ASN B 2 83  ? 15.78400  4.63500   30.96800  1.000 13.40000 ? 83  ASN B CA  1 
ATOM   2927 C C   . ASN B 2 83  ? 15.49500  4.87400   32.44400  1.000 16.06000 ? 83  ASN B C   1 
ATOM   2928 O O   . ASN B 2 83  ? 16.36200  4.64400   33.31100  1.000 13.22000 ? 83  ASN B O   1 
ATOM   2929 C CB  . ASN B 2 83  ? 15.37200  3.21800   30.57800  1.000 18.27000 ? 83  ASN B CB  1 
ATOM   2930 C CG  . ASN B 2 83  ? 13.85500  3.08700   30.32900  1.000 20.90000 ? 83  ASN B CG  1 
ATOM   2931 O OD1 . ASN B 2 83  ? 13.11800  4.08400   30.20600  1.000 18.68000 ? 83  ASN B OD1 1 
ATOM   2932 N ND2 . ASN B 2 83  ? 13.40500  1.86400   30.25300  1.000 25.91000 ? 83  ASN B ND2 1 
ATOM   2933 N N   . HIS B 2 84  ? 14.28300  5.35100   32.71600  1.000 13.15000 ? 84  HIS B N   1 
ATOM   2934 C CA  . HIS B 2 84  ? 13.86600  5.78400   34.05200  1.000 12.40000 ? 84  HIS B CA  1 
ATOM   2935 C C   . HIS B 2 84  ? 12.35600  5.74100   34.05000  1.000 15.09000 ? 84  HIS B C   1 
ATOM   2936 O O   . HIS B 2 84  ? 11.72000  5.85900   32.99100  1.000 14.29000 ? 84  HIS B O   1 
ATOM   2937 C CB  . HIS B 2 84  ? 14.36400  7.21400   34.35700  1.000 10.41000 ? 84  HIS B CB  1 
ATOM   2938 C CG  . HIS B 2 84  ? 14.14300  7.66900   35.76900  1.000 12.60000 ? 84  HIS B CG  1 
ATOM   2939 N ND1 . HIS B 2 84  ? 13.21400  8.63100   36.09500  1.000 12.83000 ? 84  HIS B ND1 1 
ATOM   2940 C CD2 . HIS B 2 84  ? 14.75500  7.32700   36.93700  1.000 13.60000 ? 84  HIS B CD2 1 
ATOM   2941 C CE1 . HIS B 2 84  ? 13.22700  8.84000   37.41000  1.000 12.63000 ? 84  HIS B CE1 1 
ATOM   2942 N NE2 . HIS B 2 84  ? 14.19600  8.09300   37.93400  1.000 13.16000 ? 84  HIS B NE2 1 
ATOM   2943 N N   . VAL B 2 85  ? 11.77600  5.58000   35.23700  1.000 13.48000 ? 85  VAL B N   1 
ATOM   2944 C CA  . VAL B 2 85  ? 10.30300  5.44900   35.31300  1.000 16.20000 ? 85  VAL B CA  1 
ATOM   2945 C C   . VAL B 2 85  ? 9.56700   6.66900   34.76300  1.000 12.48000 ? 85  VAL B C   1 
ATOM   2946 O O   . VAL B 2 85  ? 8.40300   6.55200   34.33000  1.000 13.42000 ? 85  VAL B O   1 
ATOM   2947 C CB  . VAL B 2 85  ? 9.93500   5.15400   36.79600  1.000 16.92000 ? 85  VAL B CB  1 
ATOM   2948 C CG1 . VAL B 2 85  ? 10.15500  6.38100   37.63700  1.000 13.16000 ? 85  VAL B CG1 1 
ATOM   2949 C CG2 . VAL B 2 85  ? 8.46700   4.67100   36.92400  1.000 23.46000 ? 85  VAL B CG2 1 
ATOM   2950 N N   . THR B 2 86  ? 10.21400  7.84400   34.75100  1.000 9.84000  ? 86  THR B N   1 
ATOM   2951 C CA  . THR B 2 86  ? 9.61300   9.06900   34.23500  1.000 10.59000 ? 86  THR B CA  1 
ATOM   2952 C C   . THR B 2 86  ? 9.45600   9.06500   32.70100  1.000 15.84000 ? 86  THR B C   1 
ATOM   2953 O O   . THR B 2 86  ? 8.69600   9.88500   32.16500  1.000 14.98000 ? 86  THR B O   1 
ATOM   2954 C CB  . THR B 2 86  ? 10.41500  10.31200  34.64600  1.000 16.89000 ? 86  THR B CB  1 
ATOM   2955 O OG1 . THR B 2 86  ? 11.80600  10.17900  34.25600  1.000 13.86000 ? 86  THR B OG1 1 
ATOM   2956 C CG2 . THR B 2 86  ? 10.32100  10.49500  36.14000  1.000 19.04000 ? 86  THR B CG2 1 
ATOM   2957 N N   . LEU B 2 87  ? 10.13000  8.18500   31.99200  1.000 12.53000 ? 87  LEU B N   1 
ATOM   2958 C CA  . LEU B 2 87  ? 10.23600  8.33500   30.52500  1.000 17.00000 ? 87  LEU B CA  1 
ATOM   2959 C C   . LEU B 2 87  ? 9.27400   7.40100   29.82400  1.000 18.81000 ? 87  LEU B C   1 
ATOM   2960 O O   . LEU B 2 87  ? 9.14400   6.24000   30.22200  1.000 14.16000 ? 87  LEU B O   1 
ATOM   2961 C CB  . LEU B 2 87  ? 11.64100  8.01600   29.99700  1.000 16.65000 ? 87  LEU B CB  1 
ATOM   2962 C CG  . LEU B 2 87  ? 12.75600  8.89100   30.60600  1.000 13.33000 ? 87  LEU B CG  1 
ATOM   2963 C CD1 . LEU B 2 87  ? 14.18500  8.35100   30.21900  1.000 16.22000 ? 87  LEU B CD1 1 
ATOM   2964 C CD2 . LEU B 2 87  ? 12.60500  10.32600  30.12900  1.000 17.25000 ? 87  LEU B CD2 1 
ATOM   2965 N N   . SER B 2 88  ? 8.63600   7.89000   28.73900  1.000 17.13000 ? 88  SER B N   1 
ATOM   2966 C CA  . SER B 2 88  ? 7.83000   6.98100   27.90700  1.000 18.49000 ? 88  SER B CA  1 
ATOM   2967 C C   . SER B 2 88  ? 8.66000   5.99100   27.10000  1.000 26.95000 ? 88  SER B C   1 
ATOM   2968 O O   . SER B 2 88  ? 8.14900   4.91900   26.75700  1.000 22.70000 ? 88  SER B O   1 
ATOM   2969 C CB  . SER B 2 88  ? 6.94600   7.79800   26.94200  1.000 17.62000 ? 88  SER B CB  1 
ATOM   2970 O OG  . SER B 2 88  ? 6.09200   8.61000   27.70400  1.000 17.10000 ? 88  SER B OG  1 
ATOM   2971 N N   . GLN B 2 89  ? 9.91500   6.30200   26.77800  1.000 19.61000 ? 89  GLN B N   1 
ATOM   2972 C CA  . GLN B 2 89  ? 10.82200  5.34200   26.16000  1.000 17.88000 ? 89  GLN B CA  1 
ATOM   2973 C C   . GLN B 2 89  ? 12.25100  5.79400   26.48100  1.000 15.14000 ? 89  GLN B C   1 
ATOM   2974 O O   . GLN B 2 89  ? 12.44900  6.96200   26.84300  1.000 17.93000 ? 89  GLN B O   1 
ATOM   2975 C CB  . GLN B 2 89  ? 10.62100  5.28900   24.62200  1.000 21.48000 ? 89  GLN B CB  1 
ATOM   2976 C CG  . GLN B 2 89  ? 10.80800  6.63400   24.03900  1.000 19.59000 ? 89  GLN B CG  1 
ATOM   2977 C CD  . GLN B 2 89  ? 9.52800   7.55300   24.07700  1.000 38.88000 ? 89  GLN B CD  1 
ATOM   2978 O OE1 . GLN B 2 89  ? 8.36600   7.09100   24.05500  1.000 35.34000 ? 89  GLN B OE1 1 
ATOM   2979 N NE2 . GLN B 2 89  ? 9.76400   8.84900   24.29500  1.000 35.64000 ? 89  GLN B NE2 1 
ATOM   2980 N N   . PRO B 2 90  ? 13.23500  4.90900   26.36500  1.000 16.20000 ? 90  PRO B N   1 
ATOM   2981 C CA  . PRO B 2 90  ? 14.62900  5.30100   26.68600  1.000 19.28000 ? 90  PRO B CA  1 
ATOM   2982 C C   . PRO B 2 90  ? 15.09600  6.46100   25.84000  1.000 21.07000 ? 90  PRO B C   1 
ATOM   2983 O O   . PRO B 2 90  ? 14.66300  6.63900   24.69800  1.000 19.04000 ? 90  PRO B O   1 
ATOM   2984 C CB  . PRO B 2 90  ? 15.44600  4.04600   26.36700  1.000 16.23000 ? 90  PRO B CB  1 
ATOM   2985 C CG  . PRO B 2 90  ? 14.45500  2.88000   26.40400  1.000 18.14000 ? 90  PRO B CG  1 
ATOM   2986 C CD  . PRO B 2 90  ? 13.17700  3.50600   25.88300  1.000 16.80000 ? 90  PRO B CD  1 
ATOM   2987 N N   . LYS B 2 91  ? 15.97000  7.27600   26.42500  1.000 13.85000 ? 91  LYS B N   1 
ATOM   2988 C CA  . LYS B 2 91  ? 16.50500  8.43700   25.74300  1.000 17.89000 ? 91  LYS B CA  1 
ATOM   2989 C C   . LYS B 2 91  ? 17.91200  8.05700   25.31900  1.000 17.28000 ? 91  LYS B C   1 
ATOM   2990 O O   . LYS B 2 91  ? 18.67300  7.51700   26.13300  1.000 15.45000 ? 91  LYS B O   1 
ATOM   2991 C CB  . LYS B 2 91  ? 16.57500  9.64500   26.67700  1.000 23.87000 ? 91  LYS B CB  1 
ATOM   2992 C CG  . LYS B 2 91  ? 15.70100  10.79600  26.34300  1.000 31.75000 ? 91  LYS B CG  1 
ATOM   2993 C CD  . LYS B 2 91  ? 15.71900  11.83500  27.48700  1.000 26.32000 ? 91  LYS B CD  1 
ATOM   2994 C CE  . LYS B 2 91  ? 14.29900  12.36900  27.78700  1.000 23.28000 ? 91  LYS B CE  1 
ATOM   2995 N NZ  . LYS B 2 91  ? 14.50000  13.60200  28.63400  1.000 19.59000 ? 91  LYS B NZ  1 
ATOM   2996 N N   . ILE B 2 92  ? 18.26400  8.36300   24.07300  1.000 17.29000 ? 92  ILE B N   1 
ATOM   2997 C CA  . ILE B 2 92  ? 19.61400  8.08900   23.55800  1.000 18.33000 ? 92  ILE B CA  1 
ATOM   2998 C C   . ILE B 2 92  ? 20.26100  9.45000   23.28700  1.000 21.07000 ? 92  ILE B C   1 
ATOM   2999 O O   . ILE B 2 92  ? 19.66900  10.28600  22.60000  1.000 19.50000 ? 92  ILE B O   1 
ATOM   3000 C CB  . ILE B 2 92  ? 19.54100  7.19100   22.31100  1.000 19.38000 ? 92  ILE B CB  1 
ATOM   3001 C CG1 . ILE B 2 92  ? 18.99100  5.83700   22.71000  1.000 21.43000 ? 92  ILE B CG1 1 
ATOM   3002 C CG2 . ILE B 2 92  ? 20.93200  6.97400   21.67700  1.000 20.27000 ? 92  ILE B CG2 1 
ATOM   3003 C CD1 . ILE B 2 92  ? 19.33300  4.77600   21.80000  1.000 34.76000 ? 92  ILE B CD1 1 
ATOM   3004 N N   . VAL B 2 93  ? 21.43000  9.71600   23.88200  1.000 13.77000 ? 93  VAL B N   1 
ATOM   3005 C CA  . VAL B 2 93  ? 22.14500  10.96800  23.65100  1.000 16.77000 ? 93  VAL B CA  1 
ATOM   3006 C C   . VAL B 2 93  ? 23.49500  10.62200  23.03200  1.000 16.15000 ? 93  VAL B C   1 
ATOM   3007 O O   . VAL B 2 93  ? 24.24100  9.84200   23.60300  1.000 15.19000 ? 93  VAL B O   1 
ATOM   3008 C CB  . VAL B 2 93  ? 22.32500  11.78300  24.94000  1.000 16.11000 ? 93  VAL B CB  1 
ATOM   3009 C CG1 . VAL B 2 93  ? 23.03900  13.08700  24.64000  1.000 17.04000 ? 93  VAL B CG1 1 
ATOM   3010 C CG2 . VAL B 2 93  ? 20.91600  12.11000  25.56000  1.000 18.25000 ? 93  VAL B CG2 1 
ATOM   3011 N N   . LYS B 2 94  ? 23.78600  11.15400  21.85900  1.000 16.22000 ? 94  LYS B N   1 
ATOM   3012 C CA  . LYS B 2 94  ? 24.99700  10.73600  21.16200  1.000 17.35000 ? 94  LYS B CA  1 
ATOM   3013 C C   . LYS B 2 94  ? 26.18500  11.53300  21.68400  1.000 18.38000 ? 94  LYS B C   1 
ATOM   3014 O O   . LYS B 2 94  ? 26.05700  12.69600  22.07700  1.000 13.44000 ? 94  LYS B O   1 
ATOM   3015 C CB  . LYS B 2 94  ? 24.87200  10.97000  19.65800  1.000 17.70000 ? 94  LYS B CB  1 
ATOM   3016 C CG  . LYS B 2 94  ? 23.94100  10.03400  18.99200  1.000 17.20000 ? 94  LYS B CG  1 
ATOM   3017 C CD  . LYS B 2 94  ? 23.44800  10.63800  17.70300  1.000 34.43000 ? 94  LYS B CD  1 
ATOM   3018 C CE  . LYS B 2 94  ? 22.99800  9.59000   16.73800  1.000 34.83000 ? 94  LYS B CE  1 
ATOM   3019 N NZ  . LYS B 2 94  ? 22.98800  10.19600  15.35500  1.000 45.17000 ? 94  LYS B NZ  1 
ATOM   3020 N N   . TRP B 2 95  ? 27.34100  10.89600  21.67300  1.000 13.34000 ? 95  TRP B N   1 
ATOM   3021 C CA  . TRP B 2 95  ? 28.55200  11.58300  22.06400  1.000 11.75000 ? 95  TRP B CA  1 
ATOM   3022 C C   . TRP B 2 95  ? 28.97800  12.47600  20.91000  1.000 18.63000 ? 95  TRP B C   1 
ATOM   3023 O O   . TRP B 2 95  ? 29.01300  12.02200  19.76500  1.000 17.32000 ? 95  TRP B O   1 
ATOM   3024 C CB  . TRP B 2 95  ? 29.65800  10.59400  22.39800  1.000 13.81000 ? 95  TRP B CB  1 
ATOM   3025 C CG  . TRP B 2 95  ? 30.93900  11.31600  22.72300  1.000 13.83000 ? 95  TRP B CG  1 
ATOM   3026 C CD1 . TRP B 2 95  ? 31.10800  12.37800  23.59700  1.000 14.11000 ? 95  TRP B CD1 1 
ATOM   3027 C CD2 . TRP B 2 95  ? 32.21700  11.08500  22.10100  1.000 13.53000 ? 95  TRP B CD2 1 
ATOM   3028 N NE1 . TRP B 2 95  ? 32.46700  12.78400  23.58200  1.000 18.87000 ? 95  TRP B NE1 1 
ATOM   3029 C CE2 . TRP B 2 95  ? 33.14300  12.01400  22.65300  1.000 17.03000 ? 95  TRP B CE2 1 
ATOM   3030 C CE3 . TRP B 2 95  ? 32.66200  10.17400  21.12200  1.000 18.71000 ? 95  TRP B CE3 1 
ATOM   3031 C CZ2 . TRP B 2 95  ? 34.52400  12.04000  22.27400  1.000 16.39000 ? 95  TRP B CZ2 1 
ATOM   3032 C CZ3 . TRP B 2 95  ? 34.05300  10.21500  20.72600  1.000 16.60000 ? 95  TRP B CZ3 1 
ATOM   3033 C CH2 . TRP B 2 95  ? 34.95400  11.12600  21.33300  1.000 14.29000 ? 95  TRP B CH2 1 
ATOM   3034 N N   . ASP B 2 96  ? 29.29400  13.73600  21.22300  1.000 16.45000 ? 96  ASP B N   1 
ATOM   3035 C CA  . ASP B 2 96  ? 29.81600  14.72400  20.28000  1.000 15.96000 ? 96  ASP B CA  1 
ATOM   3036 C C   . ASP B 2 96  ? 31.09200  15.24600  20.92300  1.000 17.95000 ? 96  ASP B C   1 
ATOM   3037 O O   . ASP B 2 96  ? 31.04400  15.88900  21.97300  1.000 16.48000 ? 96  ASP B O   1 
ATOM   3038 C CB  . ASP B 2 96  ? 28.79400  15.84500  20.03900  1.000 19.40000 ? 96  ASP B CB  1 
ATOM   3039 C CG  . ASP B 2 96  ? 29.29700  16.90900  19.06600  1.000 27.21000 ? 96  ASP B CG  1 
ATOM   3040 O OD1 . ASP B 2 96  ? 30.50000  17.08200  18.96600  1.000 19.72000 ? 96  ASP B OD1 1 
ATOM   3041 O OD2 . ASP B 2 96  ? 28.49800  17.58100  18.40400  1.000 24.63000 ? 96  ASP B OD2 1 
ATOM   3042 N N   . ARG B 2 97  ? 32.23100  14.97500  20.30200  1.000 15.21000 ? 97  ARG B N   1 
ATOM   3043 C CA  . ARG B 2 97  ? 33.51800  15.35300  20.90700  1.000 17.72000 ? 97  ARG B CA  1 
ATOM   3044 C C   . ARG B 2 97  ? 33.71500  16.87100  21.07000  1.000 19.68000 ? 97  ARG B C   1 
ATOM   3045 O O   . ARG B 2 97  ? 34.64600  17.30100  21.78600  1.000 20.93000 ? 97  ARG B O   1 
ATOM   3046 C CB  . ARG B 2 97  ? 34.67900  14.79100  20.05800  1.000 20.26000 ? 97  ARG B CB  1 
ATOM   3047 C CG  . ARG B 2 97  ? 34.82100  15.46200  18.69900  1.000 18.51000 ? 97  ARG B CG  1 
ATOM   3048 C CD  . ARG B 2 97  ? 35.98700  14.79700  17.95400  1.000 20.85000 ? 97  ARG B CD  1 
ATOM   3049 N NE  . ARG B 2 97  ? 35.63400  13.43000  17.54000  1.000 24.29000 ? 97  ARG B NE  1 
ATOM   3050 C CZ  . ARG B 2 97  ? 36.51700  12.44700  17.38000  1.000 21.22000 ? 97  ARG B CZ  1 
ATOM   3051 N NH1 . ARG B 2 97  ? 37.81100  12.64100  17.55200  1.000 24.20000 ? 97  ARG B NH1 1 
ATOM   3052 N NH2 . ARG B 2 97  ? 36.08600  11.23900  17.04900  1.000 27.59000 ? 97  ARG B NH2 1 
ATOM   3053 N N   . ASP B 2 98  ? 32.87800  17.68400  20.45500  1.000 16.28000 ? 98  ASP B N   1 
ATOM   3054 C CA  . ASP B 2 98  ? 32.93800  19.13000  20.64900  1.000 20.70000 ? 98  ASP B CA  1 
ATOM   3055 C C   . ASP B 2 98  ? 31.96500  19.61400  21.73400  1.000 17.74000 ? 98  ASP B C   1 
ATOM   3056 O O   . ASP B 2 98  ? 31.78800  20.82600  21.86900  1.000 18.74000 ? 98  ASP B O   1 
ATOM   3057 C CB  . ASP B 2 98  ? 32.58400  19.85400  19.34400  1.000 22.10000 ? 98  ASP B CB  1 
ATOM   3058 C CG  . ASP B 2 98  ? 33.66100  19.65900  18.24800  1.000 27.13000 ? 98  ASP B CG  1 
ATOM   3059 O OD1 . ASP B 2 98  ? 34.81700  19.39100  18.59300  1.000 28.06000 ? 98  ASP B OD1 1 
ATOM   3060 O OD2 . ASP B 2 98  ? 33.26600  19.69200  17.05200  1.000 38.96000 ? 98  ASP B OD2 1 
ATOM   3061 N N   . MET B 2 99  ? 31.27500  18.71700  22.46400  1.000 16.55000 ? 99  MET B N   1 
ATOM   3062 C CA  . MET B 2 99  ? 30.34200  19.23900  23.50500  1.000 13.25000 ? 99  MET B CA  1 
ATOM   3063 C C   . MET B 2 99  ? 30.34600  18.63200  24.95800  1.000 20.72000 ? 99  MET B C   1 
ATOM   3064 O O   . MET B 2 99  ? 31.27600  17.85300  25.21500  1.000 23.01000 ? 99  MET B O   1 
ATOM   3065 C CB  . MET B 2 99  ? 28.89300  19.16500  23.01600  1.000 18.14000 ? 99  MET B CB  1 
ATOM   3066 C CG  . MET B 2 99  ? 28.57800  19.95800  21.73100  1.000 23.88000 ? 99  MET B CG  1 
ATOM   3067 S SD  . MET B 2 99  ? 26.88300  19.48600  21.40300  1.000 43.59000 ? 99  MET B SD  1 
ATOM   3068 C CE  . MET B 2 99  ? 26.12300  21.04600  21.93000  1.000 44.30000 ? 99  MET B CE  1 
ATOM   3069 N N   . MET C 3 1   ? 34.64900  11.27500  59.23800  1.000 16.44000 ? 1   MET C N   1 
ATOM   3070 C CA  . MET C 3 1   ? 34.16000  10.50300  60.39100  1.000 15.14000 ? 1   MET C CA  1 
ATOM   3071 C C   . MET C 3 1   ? 32.65600  10.49700  60.55800  1.000 14.14000 ? 1   MET C C   1 
ATOM   3072 O O   . MET C 3 1   ? 32.07000  11.51400  60.82900  1.000 14.20000 ? 1   MET C O   1 
ATOM   3073 C CB  . MET C 3 1   ? 34.85700  11.03500  61.63700  1.000 18.11000 ? 1   MET C CB  1 
ATOM   3074 C CG  . MET C 3 1   ? 34.38600  10.57800  62.96900  1.000 22.08000 ? 1   MET C CG  1 
ATOM   3075 S SD  . MET C 3 1   ? 34.96100  8.96200   63.27300  1.000 29.29000 ? 1   MET C SD  1 
ATOM   3076 C CE  . MET C 3 1   ? 36.70300  9.04200   63.61100  1.000 23.05000 ? 1   MET C CE  1 
ATOM   3077 N N   . ALA C 3 2   ? 32.05500  9.31200   60.43700  1.000 13.42000 ? 2   ALA C N   1 
ATOM   3078 C CA  . ALA C 3 2   ? 30.60700  9.21200   60.39500  1.000 11.74000 ? 2   ALA C CA  1 
ATOM   3079 C C   . ALA C 3 2   ? 30.00500  9.23100   61.78800  1.000 16.31000 ? 2   ALA C C   1 
ATOM   3080 O O   . ALA C 3 2   ? 30.65300  8.96000   62.82000  1.000 13.50000 ? 2   ALA C O   1 
ATOM   3081 C CB  . ALA C 3 2   ? 30.13700  7.90700   59.68700  1.000 12.70000 ? 2   ALA C CB  1 
ATOM   3082 N N   . ARG C 3 3   ? 28.72500  9.53500   61.78500  1.000 12.76000 ? 3   ARG C N   1 
ATOM   3083 C CA  . ARG C 3 3   ? 27.89600  9.48900   62.98100  1.000 15.50000 ? 3   ARG C CA  1 
ATOM   3084 C C   . ARG C 3 3   ? 27.81400  8.06200   63.51900  1.000 15.55000 ? 3   ARG C C   1 
ATOM   3085 O O   . ARG C 3 3   ? 27.85500  7.10900   62.75400  1.000 13.80000 ? 3   ARG C O   1 
ATOM   3086 C CB  . ARG C 3 3   ? 26.52700  10.03000  62.58000  1.000 13.89000 ? 3   ARG C CB  1 
ATOM   3087 C CG  . ARG C 3 3   ? 25.59300  10.09000  63.68100  1.000 21.75000 ? 3   ARG C CG  1 
ATOM   3088 C CD  . ARG C 3 3   ? 25.79900  11.43100  64.38700  1.000 20.69000 ? 3   ARG C CD  1 
ATOM   3089 N NE  . ARG C 3 3   ? 24.59800  11.64800  65.15600  1.000 18.42000 ? 3   ARG C NE  1 
ATOM   3090 C CZ  . ARG C 3 3   ? 24.20400  10.84400  66.13200  1.000 20.88000 ? 3   ARG C CZ  1 
ATOM   3091 N NH1 . ARG C 3 3   ? 24.99500  9.89400   66.62300  1.000 16.44000 ? 3   ARG C NH1 1 
ATOM   3092 N NH2 . ARG C 3 3   ? 22.97500  10.96600  66.60100  1.000 16.36000 ? 3   ARG C NH2 1 
ATOM   3093 N N   . GLU C 3 4   ? 27.70500  7.90500   64.84800  1.000 15.57000 ? 4   GLU C N   1 
ATOM   3094 C CA  . GLU C 3 4   ? 27.43700  6.58000   65.39700  1.000 17.05000 ? 4   GLU C CA  1 
ATOM   3095 C C   . GLU C 3 4   ? 26.05700  6.10600   64.91600  1.000 22.59000 ? 4   GLU C C   1 
ATOM   3096 O O   . GLU C 3 4   ? 25.24900  6.87500   64.36900  1.000 18.15000 ? 4   GLU C O   1 
ATOM   3097 C CB  . GLU C 3 4   ? 27.45700  6.59000   66.93000  1.000 18.20000 ? 4   GLU C CB  1 
ATOM   3098 C CG  . GLU C 3 4   ? 28.76500  7.16500   67.52700  1.000 17.56000 ? 4   GLU C CG  1 
ATOM   3099 C CD  . GLU C 3 4   ? 29.94400  6.19000   67.38000  1.000 27.22000 ? 4   GLU C CD  1 
ATOM   3100 O OE1 . GLU C 3 4   ? 29.73900  5.00700   66.97400  1.000 23.31000 ? 4   GLU C OE1 1 
ATOM   3101 O OE2 . GLU C 3 4   ? 31.07800  6.59800   67.70800  1.000 27.62000 ? 4   GLU C OE2 1 
ATOM   3102 N N   . LEU C 3 5   ? 25.81900  4.79700   65.07200  1.000 20.55000 ? 5   LEU C N   1 
ATOM   3103 C CA  . LEU C 3 5   ? 24.52300  4.18900   64.77600  1.000 21.53000 ? 5   LEU C CA  1 
ATOM   3104 C C   . LEU C 3 5   ? 23.38900  5.03400   65.36300  1.000 17.43000 ? 5   LEU C C   1 
ATOM   3105 O O   . LEU C 3 5   ? 23.47300  5.49300   66.50700  1.000 17.23000 ? 5   LEU C O   1 
ATOM   3106 C CB  . LEU C 3 5   ? 24.47700  2.76100   65.36400  1.000 18.21000 ? 5   LEU C CB  1 
ATOM   3107 C CG  . LEU C 3 5   ? 23.08900  2.12200   65.32300  1.000 15.74000 ? 5   LEU C CG  1 
ATOM   3108 C CD1 . LEU C 3 5   ? 22.73100  1.85200   63.84700  1.000 15.56000 ? 5   LEU C CD1 1 
ATOM   3109 C CD2 . LEU C 3 5   ? 23.02000  0.81300   66.15800  1.000 20.52000 ? 5   LEU C CD2 1 
ATOM   3110 N N   . HIS C 3 6   ? 22.35300  5.24800   64.56700  1.000 17.63000 ? 6   HIS C N   1 
ATOM   3111 C CA  . HIS C 3 6   ? 21.22500  6.12300   64.91800  1.000 18.05000 ? 6   HIS C CA  1 
ATOM   3112 C C   . HIS C 3 6   ? 20.03800  5.24400   65.22500  1.000 16.21000 ? 6   HIS C C   1 
ATOM   3113 O O   . HIS C 3 6   ? 19.89000  4.18700   64.60400  1.000 17.11000 ? 6   HIS C O   1 
ATOM   3114 C CB  . HIS C 3 6   ? 20.83800  7.05300   63.75300  1.000 17.78000 ? 6   HIS C CB  1 
ATOM   3115 C CG  . HIS C 3 6   ? 19.99900  8.23200   64.16900  1.000 18.21000 ? 6   HIS C CG  1 
ATOM   3116 N ND1 . HIS C 3 6   ? 18.65200  8.13200   64.43700  1.000 16.53000 ? 6   HIS C ND1 1 
ATOM   3117 C CD2 . HIS C 3 6   ? 20.32700  9.53100   64.39500  1.000 18.03000 ? 6   HIS C CD2 1 
ATOM   3118 C CE1 . HIS C 3 6   ? 18.18500  9.30700   64.83500  1.000 17.58000 ? 6   HIS C CE1 1 
ATOM   3119 N NE2 . HIS C 3 6   ? 19.17100  10.18000  64.79900  1.000 17.46000 ? 6   HIS C NE2 1 
ATOM   3120 N N   . PRO C 3 7   ? 19.20300  5.62200   66.17700  1.000 17.77000 ? 7   PRO C N   1 
ATOM   3121 C CA  . PRO C 3 7   ? 17.95200  4.90700   66.38500  1.000 14.83000 ? 7   PRO C CA  1 
ATOM   3122 C C   . PRO C 3 7   ? 17.16600  4.79900   65.08300  1.000 14.52000 ? 7   PRO C C   1 
ATOM   3123 O O   . PRO C 3 7   ? 17.25800  5.66500   64.19600  1.000 15.84000 ? 7   PRO C O   1 
ATOM   3124 C CB  . PRO C 3 7   ? 17.22300  5.77600   67.42500  1.000 22.80000 ? 7   PRO C CB  1 
ATOM   3125 C CG  . PRO C 3 7   ? 18.34800  6.39700   68.23800  1.000 19.86000 ? 7   PRO C CG  1 
ATOM   3126 C CD  . PRO C 3 7   ? 19.42500  6.69300   67.18400  1.000 16.78000 ? 7   PRO C CD  1 
ATOM   3127 N N   . GLU C 3 8   ? 16.39800  3.71600   64.98800  1.000 14.37000 ? 8   GLU C N   1 
ATOM   3128 C CA  . GLU C 3 8   ? 15.50500  3.51100   63.85100  1.000 13.60000 ? 8   GLU C CA  1 
ATOM   3129 C C   . GLU C 3 8   ? 14.42800  4.60500   63.79100  1.000 16.87000 ? 8   GLU C C   1 
ATOM   3130 O O   . GLU C 3 8   ? 14.09900  5.26000   64.78700  1.000 12.01000 ? 8   GLU C O   1 
ATOM   3131 C CB  . GLU C 3 8   ? 14.93600  2.09400   63.94300  1.000 17.19000 ? 8   GLU C CB  1 
ATOM   3132 C CG  . GLU C 3 8   ? 16.13800  1.07000   63.67600  1.000 17.36000 ? 8   GLU C CG  1 
ATOM   3133 C CD  . GLU C 3 8   ? 16.02600  -0.33200  64.28000  1.000 28.29000 ? 8   GLU C CD  1 
ATOM   3134 O OE1 . GLU C 3 8   ? 14.98400  -0.61700  64.91500  1.000 19.48000 ? 8   GLU C OE1 1 
ATOM   3135 O OE2 . GLU C 3 8   ? 17.02400  -1.14600  64.11000  1.000 26.61000 ? 8   GLU C OE2 1 
ATOM   3136 N N   . TYR C 3 9   ? 13.90400  4.82600   62.57800  1.000 13.92000 ? 9   TYR C N   1 
ATOM   3137 C CA  . TYR C 3 9   ? 12.82500  5.78200   62.35400  1.000 14.61000 ? 9   TYR C CA  1 
ATOM   3138 C C   . TYR C 3 9   ? 11.50000  5.24000   62.92300  1.000 14.91000 ? 9   TYR C C   1 
ATOM   3139 O O   . TYR C 3 9   ? 11.40000  4.04200   63.28000  1.000 10.97000 ? 9   TYR C O   1 
ATOM   3140 C CB  . TYR C 3 9   ? 12.65800  6.06200   60.84900  1.000 14.61000 ? 9   TYR C CB  1 
ATOM   3141 C CG  . TYR C 3 9   ? 13.73300  6.92400   60.27500  1.000 12.97000 ? 9   TYR C CG  1 
ATOM   3142 C CD1 . TYR C 3 9   ? 15.05200  6.44000   60.15800  1.000 11.83000 ? 9   TYR C CD1 1 
ATOM   3143 C CD2 . TYR C 3 9   ? 13.45300  8.21500   59.80600  1.000 13.24000 ? 9   TYR C CD2 1 
ATOM   3144 C CE1 . TYR C 3 9   ? 16.05700  7.22800   59.61300  1.000 11.60000 ? 9   TYR C CE1 1 
ATOM   3145 C CE2 . TYR C 3 9   ? 14.44900  9.00800   59.22600  1.000 13.42000 ? 9   TYR C CE2 1 
ATOM   3146 C CZ  . TYR C 3 9   ? 15.75400  8.51000   59.17900  1.000 12.69000 ? 9   TYR C CZ  1 
ATOM   3147 O OH  . TYR C 3 9   ? 16.72700  9.29200   58.59900  1.000 12.35000 ? 9   TYR C OH  1 
ATOM   3148 O OXT . TYR C 3 9   ? 10.50500  5.98000   63.11300  1.000 13.55000 ? 9   TYR C OXT 1 
ATOM   3149 N N   . HIS D 1 2   ? -6.88100  3.90300   14.02100  1.000 16.39000 ? 3   HIS D N   1 
ATOM   3150 C CA  . HIS D 1 2   ? -6.67900  5.31700   13.67800  1.000 12.96000 ? 3   HIS D CA  1 
ATOM   3151 C C   . HIS D 1 2   ? -7.91600  5.91300   13.02000  1.000 14.09000 ? 3   HIS D C   1 
ATOM   3152 O O   . HIS D 1 2   ? -8.63300  5.22300   12.34800  1.000 13.57000 ? 3   HIS D O   1 
ATOM   3153 C CB  . HIS D 1 2   ? -5.47000  5.49800   12.74800  1.000 12.23000 ? 3   HIS D CB  1 
ATOM   3154 C CG  . HIS D 1 2   ? -4.18000  5.13700   13.41500  1.000 14.69000 ? 3   HIS D CG  1 
ATOM   3155 N ND1 . HIS D 1 2   ? -3.68500  5.83600   14.49400  1.000 15.76000 ? 3   HIS D ND1 1 
ATOM   3156 C CD2 . HIS D 1 2   ? -3.30100  4.14300   13.17200  1.000 16.55000 ? 3   HIS D CD2 1 
ATOM   3157 C CE1 . HIS D 1 2   ? -2.54000  5.29700   14.88300  1.000 20.11000 ? 3   HIS D CE1 1 
ATOM   3158 N NE2 . HIS D 1 2   ? -2.28200  4.26400   14.09300  1.000 17.21000 ? 3   HIS D NE2 1 
ATOM   3159 N N   . SER D 1 3   ? -8.12500  7.21300   13.18700  1.000 12.34000 ? 4   SER D N   1 
ATOM   3160 C CA  . SER D 1 3   ? -9.31300  7.87700   12.66800  1.000 9.53000  ? 4   SER D CA  1 
ATOM   3161 C C   . SER D 1 3   ? -8.96800  9.29100   12.28300  1.000 10.77000 ? 4   SER D C   1 
ATOM   3162 O O   . SER D 1 3   ? -8.09700  9.88700   12.91600  1.000 12.98000 ? 4   SER D O   1 
ATOM   3163 C CB  . SER D 1 3   ? -10.40700 7.97800   13.76400  1.000 13.31000 ? 4   SER D CB  1 
ATOM   3164 O OG  . SER D 1 3   ? -10.74900 6.66200   14.10600  1.000 26.64000 ? 4   SER D OG  1 
ATOM   3165 N N   . MET D 1 4   ? -9.73500  9.88600   11.34500  1.000 12.08000 ? 5   MET D N   1 
ATOM   3166 C CA  . MET D 1 4   ? -9.59700  11.33600  11.17100  1.000 9.69000  ? 5   MET D CA  1 
ATOM   3167 C C   . MET D 1 4   ? -10.98700 11.89000  11.37500  1.000 12.02000 ? 5   MET D C   1 
ATOM   3168 O O   . MET D 1 4   ? -11.94900 11.29000  10.85900  1.000 10.68000 ? 5   MET D O   1 
ATOM   3169 C CB  . MET D 1 4   ? -9.01700  11.75500  9.84100   1.000 8.63000  ? 5   MET D CB  1 
ATOM   3170 C CG  . MET D 1 4   ? -9.21000  13.18900  9.53400   1.000 8.15000  ? 5   MET D CG  1 
ATOM   3171 S SD  . MET D 1 4   ? -8.16100  13.72800  8.12900   1.000 14.53000 ? 5   MET D SD  1 
ATOM   3172 C CE  . MET D 1 4   ? -9.13900  13.05800  6.71500   1.000 9.71000  ? 5   MET D CE  1 
ATOM   3173 N N   . ARG D 1 5   ? -11.10800 12.94600  12.19500  1.000 8.56000  ? 6   ARG D N   1 
ATOM   3174 C CA  . ARG D 1 5   ? -12.44800 13.42200  12.55800  1.000 9.19000  ? 6   ARG D CA  1 
ATOM   3175 C C   . ARG D 1 5   ? -12.50800 14.94200  12.48900  1.000 8.90000  ? 6   ARG D C   1 
ATOM   3176 O O   . ARG D 1 5   ? -11.60400 15.60600  12.97400  1.000 8.76000  ? 6   ARG D O   1 
ATOM   3177 C CB  . ARG D 1 5   ? -12.87600 12.96300  13.97700  1.000 12.74000 ? 6   ARG D CB  1 
ATOM   3178 C CG  . ARG D 1 5   ? -12.80200 11.43200  14.13700  1.000 16.38000 ? 6   ARG D CG  1 
ATOM   3179 C CD  . ARG D 1 5   ? -13.24300 11.03400  15.55200  1.000 23.83000 ? 6   ARG D CD  1 
ATOM   3180 N NE  . ARG D 1 5   ? -13.69800 9.65000   15.53700  1.000 36.01000 ? 6   ARG D NE  1 
ATOM   3181 C CZ  . ARG D 1 5   ? -13.04200 8.62900   16.08300  1.000 40.64000 ? 6   ARG D CZ  1 
ATOM   3182 N NH1 . ARG D 1 5   ? -11.94300 8.82500   16.81200  1.000 37.38000 ? 6   ARG D NH1 1 
ATOM   3183 N NH2 . ARG D 1 5   ? -13.48100 7.37400   15.85400  1.000 41.68000 ? 6   ARG D NH2 1 
ATOM   3184 N N   . TYR D 1 6   ? -13.62900 15.47200  11.94600  1.000 9.56000  ? 7   TYR D N   1 
ATOM   3185 C CA  . TYR D 1 6   ? -13.87300 16.89100  11.82500  1.000 9.01000  ? 7   TYR D CA  1 
ATOM   3186 C C   . TYR D 1 6   ? -15.09700 17.27300  12.66500  1.000 9.60000  ? 7   TYR D C   1 
ATOM   3187 O O   . TYR D 1 6   ? -16.06800 16.50900  12.73900  1.000 9.83000  ? 7   TYR D O   1 
ATOM   3188 C CB  . TYR D 1 6   ? -14.13500 17.21500  10.37100  1.000 8.01000  ? 7   TYR D CB  1 
ATOM   3189 C CG  . TYR D 1 6   ? -12.84900 17.43700  9.64400   1.000 9.30000  ? 7   TYR D CG  1 
ATOM   3190 C CD1 . TYR D 1 6   ? -12.20700 18.68200  9.72700   1.000 12.32000 ? 7   TYR D CD1 1 
ATOM   3191 C CD2 . TYR D 1 6   ? -12.27400 16.41200  8.90600   1.000 13.27000 ? 7   TYR D CD2 1 
ATOM   3192 C CE1 . TYR D 1 6   ? -10.99100 18.94100  9.05300   1.000 12.23000 ? 7   TYR D CE1 1 
ATOM   3193 C CE2 . TYR D 1 6   ? -11.01500 16.64200  8.18900   1.000 8.79000  ? 7   TYR D CE2 1 
ATOM   3194 C CZ  . TYR D 1 6   ? -10.42600 17.90900  8.28300   1.000 12.46000 ? 7   TYR D CZ  1 
ATOM   3195 O OH  . TYR D 1 6   ? -9.24600  18.19400  7.62200   1.000 10.34000 ? 7   TYR D OH  1 
ATOM   3196 N N   . PHE D 1 7   ? -15.05800 18.46800  13.26500  1.000 7.72000  ? 8   PHE D N   1 
ATOM   3197 C CA  . PHE D 1 7   ? -16.12100 18.90600  14.17800  1.000 9.69000  ? 8   PHE D CA  1 
ATOM   3198 C C   . PHE D 1 7   ? -16.44700 20.32500  13.78000  1.000 8.99000  ? 8   PHE D C   1 
ATOM   3199 O O   . PHE D 1 7   ? -15.57800 21.18500  13.92400  1.000 9.50000  ? 8   PHE D O   1 
ATOM   3200 C CB  . PHE D 1 7   ? -15.68300 18.86300  15.64700  1.000 8.90000  ? 8   PHE D CB  1 
ATOM   3201 C CG  . PHE D 1 7   ? -15.28700 17.46200  16.11100  1.000 10.54000 ? 8   PHE D CG  1 
ATOM   3202 C CD1 . PHE D 1 7   ? -14.06400 16.94400  15.84600  1.000 11.22000 ? 8   PHE D CD1 1 
ATOM   3203 C CD2 . PHE D 1 7   ? -16.20600 16.67000  16.81700  1.000 12.65000 ? 8   PHE D CD2 1 
ATOM   3204 C CE1 . PHE D 1 7   ? -13.75200 15.58400  16.20800  1.000 11.97000 ? 8   PHE D CE1 1 
ATOM   3205 C CE2 . PHE D 1 7   ? -15.90100 15.31600  17.21900  1.000 14.29000 ? 8   PHE D CE2 1 
ATOM   3206 C CZ  . PHE D 1 7   ? -14.67500 14.80500  16.93700  1.000 14.18000 ? 8   PHE D CZ  1 
ATOM   3207 N N   . TYR D 1 8   ? -17.67600 20.55600  13.29300  1.000 7.35000  ? 9   TYR D N   1 
ATOM   3208 C CA  . TYR D 1 8   ? -18.11800 21.88400  12.87800  1.000 7.68000  ? 9   TYR D CA  1 
ATOM   3209 C C   . TYR D 1 8   ? -19.18600 22.38400  13.83300  1.000 9.50000  ? 9   TYR D C   1 
ATOM   3210 O O   . TYR D 1 8   ? -20.12500 21.63500  14.13200  1.000 8.57000  ? 9   TYR D O   1 
ATOM   3211 C CB  . TYR D 1 8   ? -18.75800 21.91300  11.44600  1.000 7.55000  ? 9   TYR D CB  1 
ATOM   3212 C CG  . TYR D 1 8   ? -17.83000 21.55500  10.31900  1.000 9.06000  ? 9   TYR D CG  1 
ATOM   3213 C CD1 . TYR D 1 8   ? -16.46900 21.29200  10.54600  1.000 9.95000  ? 9   TYR D CD1 1 
ATOM   3214 C CD2 . TYR D 1 8   ? -18.33200 21.46700  8.99700   1.000 11.34000 ? 9   TYR D CD2 1 
ATOM   3215 C CE1 . TYR D 1 8   ? -15.62100 20.91800  9.44000   1.000 9.16000  ? 9   TYR D CE1 1 
ATOM   3216 C CE2 . TYR D 1 8   ? -17.47900 21.14300  7.90800   1.000 10.14000 ? 9   TYR D CE2 1 
ATOM   3217 C CZ  . TYR D 1 8   ? -16.15700 20.84100  8.14900   1.000 13.93000 ? 9   TYR D CZ  1 
ATOM   3218 O OH  . TYR D 1 8   ? -15.38700 20.50900  7.01900   1.000 12.42000 ? 9   TYR D OH  1 
ATOM   3219 N N   . THR D 1 9   ? -19.06900 23.67100  14.24100  1.000 8.31000  ? 10  THR D N   1 
ATOM   3220 C CA  . THR D 1 9   ? -20.09600 24.31800  15.08600  1.000 7.80000  ? 10  THR D CA  1 
ATOM   3221 C C   . THR D 1 9   ? -20.43600 25.67300  14.50000  1.000 11.14000 ? 10  THR D C   1 
ATOM   3222 O O   . THR D 1 9   ? -19.54300 26.51700  14.34600  1.000 8.68000  ? 10  THR D O   1 
ATOM   3223 C CB  . THR D 1 9   ? -19.56000 24.49200  16.52000  1.000 9.80000  ? 10  THR D CB  1 
ATOM   3224 O OG1 . THR D 1 9   ? -19.10800 23.23400  17.01100  1.000 8.84000  ? 10  THR D OG1 1 
ATOM   3225 C CG2 . THR D 1 9   ? -20.65900 25.04600  17.43700  1.000 9.99000  ? 10  THR D CG2 1 
ATOM   3226 N N   . ALA D 1 10  ? -21.72600 25.91300  14.19600  1.000 9.73000  ? 11  ALA D N   1 
ATOM   3227 C CA  . ALA D 1 10  ? -22.18400 27.22100  13.77100  1.000 9.06000  ? 11  ALA D CA  1 
ATOM   3228 C C   . ALA D 1 10  ? -23.23200 27.70000  14.75900  1.000 8.91000  ? 11  ALA D C   1 
ATOM   3229 O O   . ALA D 1 10  ? -24.10300 26.91600  15.14700  1.000 8.90000  ? 11  ALA D O   1 
ATOM   3230 C CB  . ALA D 1 10  ? -22.80500 27.17900  12.34700  1.000 7.99000  ? 11  ALA D CB  1 
ATOM   3231 N N   . VAL D 1 11  ? -23.13300 28.96400  15.16900  1.000 8.43000  ? 12  VAL D N   1 
ATOM   3232 C CA  . VAL D 1 11  ? -23.95500 29.50500  16.25500  1.000 9.78000  ? 12  VAL D CA  1 
ATOM   3233 C C   . VAL D 1 11  ? -24.48800 30.86300  15.81300  1.000 12.07000 ? 12  VAL D C   1 
ATOM   3234 O O   . VAL D 1 11  ? -23.69700 31.76400  15.54900  1.000 10.21000 ? 12  VAL D O   1 
ATOM   3235 C CB  . VAL D 1 11  ? -23.15600 29.63500  17.57500  1.000 9.88000  ? 12  VAL D CB  1 
ATOM   3236 C CG1 . VAL D 1 11  ? -24.07500 30.12700  18.75600  1.000 12.92000 ? 12  VAL D CG1 1 
ATOM   3237 C CG2 . VAL D 1 11  ? -22.56200 28.27900  17.91200  1.000 9.68000  ? 12  VAL D CG2 1 
ATOM   3238 N N   . SER D 1 12  ? -25.82000 31.03300  15.79800  1.000 8.38000  ? 13  SER D N   1 
ATOM   3239 C CA  . SER D 1 12  ? -26.35700 32.35000  15.42300  1.000 8.57000  ? 13  SER D CA  1 
ATOM   3240 C C   . SER D 1 12  ? -26.31700 33.28400  16.63800  1.000 13.92000 ? 13  SER D C   1 
ATOM   3241 O O   . SER D 1 12  ? -26.24500 32.84600  17.78900  1.000 11.92000 ? 13  SER D O   1 
ATOM   3242 C CB  . SER D 1 12  ? -27.76300 32.19800  14.84500  1.000 10.49000 ? 13  SER D CB  1 
ATOM   3243 O OG  . SER D 1 12  ? -28.68400 31.68600  15.87200  1.000 12.84000 ? 13  SER D OG  1 
ATOM   3244 N N   . ARG D 1 13  ? -26.30400 34.59300  16.38500  1.000 8.82000  ? 14  ARG D N   1 
ATOM   3245 C CA  . ARG D 1 13  ? -26.20300 35.58700  17.45500  1.000 14.57000 ? 14  ARG D CA  1 
ATOM   3246 C C   . ARG D 1 13  ? -26.98000 36.81100  17.00600  1.000 12.43000 ? 14  ARG D C   1 
ATOM   3247 O O   . ARG D 1 13  ? -26.40800 37.86100  16.67300  1.000 12.10000 ? 14  ARG D O   1 
ATOM   3248 C CB  . ARG D 1 13  ? -24.74700 35.92000  17.78000  1.000 16.49000 ? 14  ARG D CB  1 
ATOM   3249 C CG  . ARG D 1 13  ? -23.90100 36.19400  16.51300  1.000 17.66000 ? 14  ARG D CG  1 
ATOM   3250 C CD  . ARG D 1 13  ? -22.38200 36.23800  16.84900  1.000 15.19000 ? 14  ARG D CD  1 
ATOM   3251 N NE  . ARG D 1 13  ? -21.66700 36.34900  15.57100  1.000 14.05000 ? 14  ARG D NE  1 
ATOM   3252 C CZ  . ARG D 1 13  ? -20.34100 36.35100  15.43500  1.000 19.12000 ? 14  ARG D CZ  1 
ATOM   3253 N NH1 . ARG D 1 13  ? -19.53700 36.30400  16.48500  1.000 17.27000 ? 14  ARG D NH1 1 
ATOM   3254 N NH2 . ARG D 1 13  ? -19.81300 36.32100  14.20400  1.000 12.34000 ? 14  ARG D NH2 1 
ATOM   3255 N N   . PRO D 1 14  ? -28.30900 36.69800  16.98900  1.000 13.43000 ? 15  PRO D N   1 
ATOM   3256 C CA  . PRO D 1 14  ? -29.17600 37.73500  16.38600  1.000 13.43000 ? 15  PRO D CA  1 
ATOM   3257 C C   . PRO D 1 14  ? -28.96200 39.04800  17.08900  1.000 13.32000 ? 15  PRO D C   1 
ATOM   3258 O O   . PRO D 1 14  ? -28.94300 39.10900  18.32100  1.000 15.39000 ? 15  PRO D O   1 
ATOM   3259 C CB  . PRO D 1 14  ? -30.58800 37.21700  16.66400  1.000 17.24000 ? 15  PRO D CB  1 
ATOM   3260 C CG  . PRO D 1 14  ? -30.42100 35.70200  16.90200  1.000 20.63000 ? 15  PRO D CG  1 
ATOM   3261 C CD  . PRO D 1 14  ? -29.06500 35.53500  17.51500  1.000 15.34000 ? 15  PRO D CD  1 
ATOM   3262 N N   . GLY D 1 15  ? -28.78500 40.09700  16.32100  1.000 16.71000 ? 16  GLY D N   1 
ATOM   3263 C CA  . GLY D 1 15  ? -28.50300 41.35100  16.94700  1.000 17.33000 ? 16  GLY D CA  1 
ATOM   3264 C C   . GLY D 1 15  ? -27.02900 41.61900  17.03500  1.000 17.99000 ? 16  GLY D C   1 
ATOM   3265 O O   . GLY D 1 15  ? -26.62800 42.76000  17.31100  1.000 15.76000 ? 16  GLY D O   1 
ATOM   3266 N N   . ARG D 1 16  ? -26.21800 40.60000  16.80800  1.000 14.23000 ? 17  ARG D N   1 
ATOM   3267 C CA  . ARG D 1 16  ? -24.81000 40.72000  16.88100  1.000 12.28000 ? 17  ARG D CA  1 
ATOM   3268 C C   . ARG D 1 16  ? -24.06500 40.24800  15.61400  1.000 15.33000 ? 17  ARG D C   1 
ATOM   3269 O O   . ARG D 1 16  ? -23.00400 39.73000  15.69800  1.000 17.21000 ? 17  ARG D O   1 
ATOM   3270 C CB  . ARG D 1 16  ? -24.28000 40.01900  18.13300  1.000 15.04000 ? 17  ARG D CB  1 
ATOM   3271 C CG  . ARG D 1 16  ? -24.69000 40.63200  19.45800  1.000 21.49000 ? 17  ARG D CG  1 
ATOM   3272 C CD  . ARG D 1 16  ? -24.14900 39.85800  20.64900  1.000 24.64000 ? 17  ARG D CD  1 
ATOM   3273 N NE  . ARG D 1 16  ? -24.98200 38.70400  20.83500  1.000 35.39000 ? 17  ARG D NE  1 
ATOM   3274 C CZ  . ARG D 1 16  ? -24.56700 37.45200  20.90800  1.000 44.88000 ? 17  ARG D CZ  1 
ATOM   3275 N NH1 . ARG D 1 16  ? -23.27400 37.16800  20.87400  1.000 45.15000 ? 17  ARG D NH1 1 
ATOM   3276 N NH2 . ARG D 1 16  ? -25.45000 36.46900  20.99000  1.000 39.05000 ? 17  ARG D NH2 1 
ATOM   3277 N N   . GLY D 1 17  ? -24.66000 40.40200  14.45500  1.000 14.35000 ? 18  GLY D N   1 
ATOM   3278 C CA  . GLY D 1 17  ? -23.95300 40.00000  13.25400  1.000 15.97000 ? 18  GLY D CA  1 
ATOM   3279 C C   . GLY D 1 17  ? -24.34700 38.61800  12.77900  1.000 18.43000 ? 18  GLY D C   1 
ATOM   3280 O O   . GLY D 1 17  ? -25.29000 37.99500  13.28500  1.000 14.49000 ? 18  GLY D O   1 
ATOM   3281 N N   . GLU D 1 18  ? -23.61800 38.14200  11.75800  1.000 14.22000 ? 19  GLU D N   1 
ATOM   3282 C CA  . GLU D 1 18  ? -23.97900 36.85700  11.17500  1.000 16.73000 ? 19  GLU D CA  1 
ATOM   3283 C C   . GLU D 1 18  ? -23.41400 35.72400  12.03400  1.000 11.80000 ? 19  GLU D C   1 
ATOM   3284 O O   . GLU D 1 18  ? -22.52700 35.96200  12.85200  1.000 13.04000 ? 19  GLU D O   1 
ATOM   3285 C CB  . GLU D 1 18  ? -23.42900 36.68900  9.76600   1.000 19.35000 ? 19  GLU D CB  1 
ATOM   3286 C CG  . GLU D 1 18  ? -22.04600 37.03100  9.67400   1.000 21.60000 ? 19  GLU D CG  1 
ATOM   3287 C CD  . GLU D 1 18  ? -21.53800 36.96200  8.21400   1.000 33.43000 ? 19  GLU D CD  1 
ATOM   3288 O OE1 . GLU D 1 18  ? -22.38200 36.88500  7.22100   1.000 24.50000 ? 19  GLU D OE1 1 
ATOM   3289 O OE2 . GLU D 1 18  ? -20.27700 37.01400  8.09100   1.000 26.97000 ? 19  GLU D OE2 1 
ATOM   3290 N N   . PRO D 1 19  ? -23.95800 34.50300  11.88600  1.000 13.52000 ? 20  PRO D N   1 
ATOM   3291 C CA  . PRO D 1 19  ? -23.48300 33.37800  12.68800  1.000 12.12000 ? 20  PRO D CA  1 
ATOM   3292 C C   . PRO D 1 19  ? -21.98300 33.15800  12.58300  1.000 13.76000 ? 20  PRO D C   1 
ATOM   3293 O O   . PRO D 1 19  ? -21.37900 33.32800  11.52400  1.000 13.12000 ? 20  PRO D O   1 
ATOM   3294 C CB  . PRO D 1 19  ? -24.22400 32.16600  12.09700  1.000 11.35000 ? 20  PRO D CB  1 
ATOM   3295 C CG  . PRO D 1 19  ? -25.60600 32.79700  11.57400  1.000 12.37000 ? 20  PRO D CG  1 
ATOM   3296 C CD  . PRO D 1 19  ? -25.13900 34.15600  11.05100  1.000 13.89000 ? 20  PRO D CD  1 
ATOM   3297 N N   . ARG D 1 20  ? -21.42900 32.66200  13.67700  1.000 11.61000 ? 21  ARG D N   1 
ATOM   3298 C CA  . ARG D 1 20  ? -20.00900 32.32100  13.75000  1.000 13.21000 ? 21  ARG D CA  1 
ATOM   3299 C C   . ARG D 1 20  ? -19.81500 30.83800  13.45200  1.000 12.60000 ? 21  ARG D C   1 
ATOM   3300 O O   . ARG D 1 20  ? -20.55100 30.00000  13.97500  1.000 13.03000 ? 21  ARG D O   1 
ATOM   3301 C CB  . ARG D 1 20  ? -19.45700 32.68000  15.13000  1.000 12.47000 ? 21  ARG D CB  1 
ATOM   3302 C CG  . ARG D 1 20  ? -17.87900 32.44700  15.18900  1.000 15.28000 ? 21  ARG D CG  1 
ATOM   3303 C CD  . ARG D 1 20  ? -17.38900 32.75500  16.57300  1.000 13.98000 ? 21  ARG D CD  1 
ATOM   3304 N NE  . ARG D 1 20  ? -15.93400 32.77000  16.76300  1.000 14.11000 ? 21  ARG D NE  1 
ATOM   3305 C CZ  . ARG D 1 20  ? -15.39200 33.04300  17.93500  1.000 19.71000 ? 21  ARG D CZ  1 
ATOM   3306 N NH1 . ARG D 1 20  ? -16.15300 33.28700  18.99600  1.000 23.94000 ? 21  ARG D NH1 1 
ATOM   3307 N NH2 . ARG D 1 20  ? -14.06100 33.08000  18.05200  1.000 16.62000 ? 21  ARG D NH2 1 
ATOM   3308 N N   . PHE D 1 21  ? -18.83400 30.50500  12.59300  1.000 9.90000  ? 22  PHE D N   1 
ATOM   3309 C CA  . PHE D 1 21  ? -18.56100 29.11400  12.24200  1.000 8.84000  ? 22  PHE D CA  1 
ATOM   3310 C C   . PHE D 1 21  ? -17.15600 28.71500  12.72100  1.000 9.49000  ? 22  PHE D C   1 
ATOM   3311 O O   . PHE D 1 21  ? -16.19600 29.44300  12.47600  1.000 8.89000  ? 22  PHE D O   1 
ATOM   3312 C CB  . PHE D 1 21  ? -18.67600 28.96200  10.73600  1.000 9.73000  ? 22  PHE D CB  1 
ATOM   3313 C CG  . PHE D 1 21  ? -18.24800 27.61200  10.21500  1.000 11.02000 ? 22  PHE D CG  1 
ATOM   3314 C CD1 . PHE D 1 21  ? -19.15400 26.58300  10.12700  1.000 12.46000 ? 22  PHE D CD1 1 
ATOM   3315 C CD2 . PHE D 1 21  ? -16.93300 27.39300  9.79300   1.000 8.27000  ? 22  PHE D CD2 1 
ATOM   3316 C CE1 . PHE D 1 21  ? -18.74200 25.27600  9.65700   1.000 12.43000 ? 22  PHE D CE1 1 
ATOM   3317 C CE2 . PHE D 1 21  ? -16.49900 26.14600  9.33100   1.000 9.89000  ? 22  PHE D CE2 1 
ATOM   3318 C CZ  . PHE D 1 21  ? -17.41500 25.08300  9.24300   1.000 13.13000 ? 22  PHE D CZ  1 
ATOM   3319 N N   . ILE D 1 22  ? -17.03600 27.59900  13.43800  1.000 8.76000  ? 23  ILE D N   1 
ATOM   3320 C CA  . ILE D 1 22  ? -15.74600 27.08800  13.92000  1.000 8.83000  ? 23  ILE D CA  1 
ATOM   3321 C C   . ILE D 1 22  ? -15.60200 25.67500  13.39900  1.000 10.24000 ? 23  ILE D C   1 
ATOM   3322 O O   . ILE D 1 22  ? -16.54700 24.89000  13.52800  1.000 10.50000 ? 23  ILE D O   1 
ATOM   3323 C CB  . ILE D 1 22  ? -15.68700 27.03600  15.45800  1.000 9.75000  ? 23  ILE D CB  1 
ATOM   3324 C CG1 . ILE D 1 22  ? -15.93500 28.38700  16.06000  1.000 12.26000 ? 23  ILE D CG1 1 
ATOM   3325 C CG2 . ILE D 1 22  ? -14.34800 26.44700  15.93100  1.000 12.53000 ? 23  ILE D CG2 1 
ATOM   3326 C CD1 . ILE D 1 22  ? -14.83600 29.16400  16.17000  1.000 19.42000 ? 23  ILE D CD1 1 
ATOM   3327 N N   . ALA D 1 23  ? -14.41700 25.32000  12.87000  1.000 8.43000  ? 24  ALA D N   1 
ATOM   3328 C CA  . ALA D 1 23  ? -14.16000 23.94500  12.48200  1.000 8.18000  ? 24  ALA D CA  1 
ATOM   3329 C C   . ALA D 1 23  ? -12.86900 23.52100  13.16500  1.000 9.63000  ? 24  ALA D C   1 
ATOM   3330 O O   . ALA D 1 23  ? -11.94600 24.31600  13.19400  1.000 8.40000  ? 24  ALA D O   1 
ATOM   3331 C CB  . ALA D 1 23  ? -13.92700 23.81600  10.97200  1.000 9.51000  ? 24  ALA D CB  1 
ATOM   3332 N N   . VAL D 1 24  ? -12.78200 22.26400  13.57900  1.000 7.29000  ? 25  VAL D N   1 
ATOM   3333 C CA  . VAL D 1 24  ? -11.51700 21.69000  14.06100  1.000 8.36000  ? 25  VAL D CA  1 
ATOM   3334 C C   . VAL D 1 24  ? -11.40300 20.26900  13.51800  1.000 11.48000 ? 25  VAL D C   1 
ATOM   3335 O O   . VAL D 1 24  ? -12.42000 19.60300  13.28600  1.000 10.92000 ? 25  VAL D O   1 
ATOM   3336 C CB  . VAL D 1 24  ? -11.38900 21.66900  15.61500  1.000 11.06000 ? 25  VAL D CB  1 
ATOM   3337 C CG1 . VAL D 1 24  ? -11.34200 23.12500  16.21300  1.000 10.02000 ? 25  VAL D CG1 1 
ATOM   3338 C CG2 . VAL D 1 24  ? -12.46600 20.87600  16.22600  1.000 11.26000 ? 25  VAL D CG2 1 
ATOM   3339 N N   . GLY D 1 25  ? -10.17300 19.84100  13.22100  1.000 10.43000 ? 26  GLY D N   1 
ATOM   3340 C CA  . GLY D 1 25  ? -9.93700  18.50000  12.70900  1.000 8.65000  ? 26  GLY D CA  1 
ATOM   3341 C C   . GLY D 1 25  ? -8.87200  17.80500  13.54400  1.000 11.28000 ? 26  GLY D C   1 
ATOM   3342 O O   . GLY D 1 25  ? -7.90300  18.43500  14.00100  1.000 9.16000  ? 26  GLY D O   1 
ATOM   3343 N N   . TYR D 1 26  ? -9.05100  16.51000  13.73400  1.000 8.61000  ? 27  TYR D N   1 
ATOM   3344 C CA  . TYR D 1 26  ? -8.20400  15.68800  14.59800  1.000 8.90000  ? 27  TYR D CA  1 
ATOM   3345 C C   . TYR D 1 26  ? -7.77800  14.47000  13.80400  1.000 13.98000 ? 27  TYR D C   1 
ATOM   3346 O O   . TYR D 1 26  ? -8.54900  13.96200  13.00200  1.000 9.38000  ? 27  TYR D O   1 
ATOM   3347 C CB  . TYR D 1 26  ? -8.92800  15.14100  15.83000  1.000 10.85000 ? 27  TYR D CB  1 
ATOM   3348 C CG  . TYR D 1 26  ? -9.24600  16.17000  16.91500  1.000 12.17000 ? 27  TYR D CG  1 
ATOM   3349 C CD1 . TYR D 1 26  ? -10.33400 17.07200  16.76500  1.000 15.82000 ? 27  TYR D CD1 1 
ATOM   3350 C CD2 . TYR D 1 26  ? -8.49500  16.23900  18.05200  1.000 12.52000 ? 27  TYR D CD2 1 
ATOM   3351 C CE1 . TYR D 1 26  ? -10.63200 17.99300  17.77300  1.000 16.06000 ? 27  TYR D CE1 1 
ATOM   3352 C CE2 . TYR D 1 26  ? -8.78300  17.16800  19.06300  1.000 12.09000 ? 27  TYR D CE2 1 
ATOM   3353 C CZ  . TYR D 1 26  ? -9.81200  18.02500  18.90400  1.000 18.35000 ? 27  TYR D CZ  1 
ATOM   3354 O OH  . TYR D 1 26  ? -10.06100 18.90200  19.93100  1.000 27.95000 ? 27  TYR D OH  1 
ATOM   3355 N N   . VAL D 1 27  ? -6.57200  13.97000  14.08300  1.000 9.94000  ? 28  VAL D N   1 
ATOM   3356 C CA  . VAL D 1 27  ? -6.21900  12.57300  13.81200  1.000 11.91000 ? 28  VAL D CA  1 
ATOM   3357 C C   . VAL D 1 27  ? -6.12800  11.91000  15.19000  1.000 10.93000 ? 28  VAL D C   1 
ATOM   3358 O O   . VAL D 1 27  ? -5.38900  12.39700  16.04500  1.000 11.03000 ? 28  VAL D O   1 
ATOM   3359 C CB  . VAL D 1 27  ? -4.88300  12.42300  13.07100  1.000 13.88000 ? 28  VAL D CB  1 
ATOM   3360 C CG1 . VAL D 1 27  ? -4.53800  10.89500  13.02300  1.000 10.86000 ? 28  VAL D CG1 1 
ATOM   3361 C CG2 . VAL D 1 27  ? -4.99200  13.00500  11.65300  1.000 12.96000 ? 28  VAL D CG2 1 
ATOM   3362 N N   . ASP D 1 28  ? -6.95800  10.89300  15.43200  1.000 11.37000 ? 29  ASP D N   1 
ATOM   3363 C CA  . ASP D 1 28  ? -7.01800  10.32400  16.76700  1.000 10.86000 ? 29  ASP D CA  1 
ATOM   3364 C C   . ASP D 1 28  ? -7.26500  11.42300  17.77900  1.000 15.85000 ? 29  ASP D C   1 
ATOM   3365 O O   . ASP D 1 28  ? -8.24600  12.17100  17.64500  1.000 11.44000 ? 29  ASP D O   1 
ATOM   3366 C CB  . ASP D 1 28  ? -5.72600  9.55600   17.05500  1.000 11.96000 ? 29  ASP D CB  1 
ATOM   3367 C CG  . ASP D 1 28  ? -5.52100  8.43800   16.04900  1.000 16.35000 ? 29  ASP D CG  1 
ATOM   3368 O OD1 . ASP D 1 28  ? -6.56600  7.89400   15.61600  1.000 18.09000 ? 29  ASP D OD1 1 
ATOM   3369 O OD2 . ASP D 1 28  ? -4.36400  8.06400   15.74800  1.000 16.55000 ? 29  ASP D OD2 1 
ATOM   3370 N N   . ASP D 1 29  ? -6.41600  11.53500  18.82000  1.000 12.64000 ? 30  ASP D N   1 
ATOM   3371 C CA  . ASP D 1 29  ? -6.66000  12.55800  19.84800  1.000 13.34000 ? 30  ASP D CA  1 
ATOM   3372 C C   . ASP D 1 29  ? -5.75000  13.75400  19.67900  1.000 15.57000 ? 30  ASP D C   1 
ATOM   3373 O O   . ASP D 1 29  ? -5.46100  14.45100  20.66800  1.000 15.00000 ? 30  ASP D O   1 
ATOM   3374 C CB  . ASP D 1 29  ? -6.50100  11.99500  21.26500  1.000 12.75000 ? 30  ASP D CB  1 
ATOM   3375 C CG  . ASP D 1 29  ? -7.48800  10.83200  21.54400  1.000 14.59000 ? 30  ASP D CG  1 
ATOM   3376 O OD1 . ASP D 1 29  ? -8.67000  10.96900  21.19700  1.000 12.55000 ? 30  ASP D OD1 1 
ATOM   3377 O OD2 . ASP D 1 29  ? -7.04500  9.73900   21.98000  1.000 14.85000 ? 30  ASP D OD2 1 
ATOM   3378 N N   . THR D 1 30  ? -5.26300  13.97400  18.46400  1.000 10.36000 ? 31  THR D N   1 
ATOM   3379 C CA  . THR D 1 30  ? -4.36700  15.09100  18.14400  1.000 9.33000  ? 31  THR D CA  1 
ATOM   3380 C C   . THR D 1 30  ? -5.03100  16.04900  17.15700  1.000 8.85000  ? 31  THR D C   1 
ATOM   3381 O O   . THR D 1 30  ? -5.26200  15.69500  15.99600  1.000 11.58000 ? 31  THR D O   1 
ATOM   3382 C CB  . THR D 1 30  ? -3.04000  14.55100  17.56400  1.000 11.79000 ? 31  THR D CB  1 
ATOM   3383 O OG1 . THR D 1 30  ? -2.45600  13.67200  18.55600  1.000 10.53000 ? 31  THR D OG1 1 
ATOM   3384 C CG2 . THR D 1 30  ? -2.05600  15.65700  17.34700  1.000 13.43000 ? 31  THR D CG2 1 
ATOM   3385 N N   . GLN D 1 31  ? -5.26100  17.28500  17.59400  1.000 8.27000  ? 32  GLN D N   1 
ATOM   3386 C CA  . GLN D 1 31  ? -5.81500  18.28300  16.68700  1.000 12.37000 ? 32  GLN D CA  1 
ATOM   3387 C C   . GLN D 1 31  ? -4.76300  18.70100  15.67000  1.000 13.63000 ? 32  GLN D C   1 
ATOM   3388 O O   . GLN D 1 31  ? -3.57300  18.87900  16.01500  1.000 9.66000  ? 32  GLN D O   1 
ATOM   3389 C CB  . GLN D 1 31  ? -6.26300  19.50200  17.46900  1.000 10.69000 ? 32  GLN D CB  1 
ATOM   3390 C CG  . GLN D 1 31  ? -7.01600  20.47000  16.54900  1.000 11.88000 ? 32  GLN D CG  1 
ATOM   3391 C CD  . GLN D 1 31  ? -7.25800  21.82800  17.26400  1.000 19.61000 ? 32  GLN D CD  1 
ATOM   3392 O OE1 . GLN D 1 31  ? -6.95200  21.94800  18.42400  1.000 17.11000 ? 32  GLN D OE1 1 
ATOM   3393 N NE2 . GLN D 1 31  ? -7.87400  22.76400  16.59600  1.000 9.99000  ? 32  GLN D NE2 1 
ATOM   3394 N N   . PHE D 1 32  ? -5.19200  18.92700  14.43500  1.000 9.59000  ? 33  PHE D N   1 
ATOM   3395 C CA  . PHE D 1 32  ? -4.23900  19.41600  13.43400  1.000 8.97000  ? 33  PHE D CA  1 
ATOM   3396 C C   . PHE D 1 32  ? -4.69400  20.63800  12.66500  1.000 10.57000 ? 33  PHE D C   1 
ATOM   3397 O O   . PHE D 1 32  ? -3.85200  21.23300  11.98000  1.000 11.26000 ? 33  PHE D O   1 
ATOM   3398 C CB  . PHE D 1 32  ? -3.82300  18.30000  12.42200  1.000 9.26000  ? 33  PHE D CB  1 
ATOM   3399 C CG  . PHE D 1 32  ? -4.92800  17.83200  11.51800  1.000 9.02000  ? 33  PHE D CG  1 
ATOM   3400 C CD1 . PHE D 1 32  ? -5.80800  16.85500  11.95500  1.000 9.94000  ? 33  PHE D CD1 1 
ATOM   3401 C CD2 . PHE D 1 32  ? -5.13500  18.41100  10.25800  1.000 8.30000  ? 33  PHE D CD2 1 
ATOM   3402 C CE1 . PHE D 1 32  ? -6.81500  16.39900  11.17000  1.000 9.72000  ? 33  PHE D CE1 1 
ATOM   3403 C CE2 . PHE D 1 32  ? -6.15300  17.99900  9.43400   1.000 8.93000  ? 33  PHE D CE2 1 
ATOM   3404 C CZ  . PHE D 1 32  ? -7.04000  16.96400  9.89600   1.000 12.84000 ? 33  PHE D CZ  1 
ATOM   3405 N N   . VAL D 1 33  ? -5.96100  21.06500  12.78700  1.000 10.76000 ? 34  VAL D N   1 
ATOM   3406 C CA  . VAL D 1 33  ? -6.40700  22.22000  12.03300  1.000 10.28000 ? 34  VAL D CA  1 
ATOM   3407 C C   . VAL D 1 33  ? -7.47200  22.93500  12.83100  1.000 9.10000  ? 34  VAL D C   1 
ATOM   3408 O O   . VAL D 1 33  ? -8.24600  22.30400  13.56900  1.000 10.78000 ? 34  VAL D O   1 
ATOM   3409 C CB  . VAL D 1 33  ? -6.87700  21.78000  10.62300  1.000 7.78000  ? 34  VAL D CB  1 
ATOM   3410 C CG1 . VAL D 1 33  ? -8.06300  20.81500  10.68300  1.000 10.52000 ? 34  VAL D CG1 1 
ATOM   3411 C CG2 . VAL D 1 33  ? -7.26200  22.98400  9.75700   1.000 9.99000  ? 34  VAL D CG2 1 
ATOM   3412 N N   . ARG D 1 34  ? -7.59000  24.23400  12.58900  1.000 9.45000  ? 35  ARG D N   1 
ATOM   3413 C CA  . ARG D 1 34  ? -8.78000  24.96100  13.05200  1.000 9.59000  ? 35  ARG D CA  1 
ATOM   3414 C C   . ARG D 1 34  ? -9.12300  26.00700  12.02100  1.000 12.63000 ? 35  ARG D C   1 
ATOM   3415 O O   . ARG D 1 34  ? -8.30500  26.35800  11.17200  1.000 9.61000  ? 35  ARG D O   1 
ATOM   3416 C CB  . ARG D 1 34  ? -8.55200  25.66000  14.41800  1.000 10.75000 ? 35  ARG D CB  1 
ATOM   3417 C CG  . ARG D 1 34  ? -7.50900  26.78800  14.27600  1.000 13.63000 ? 35  ARG D CG  1 
ATOM   3418 C CD  . ARG D 1 34  ? -7.38700  27.61600  15.52900  1.000 20.61000 ? 35  ARG D CD  1 
ATOM   3419 N NE  . ARG D 1 34  ? -6.36200  28.66900  15.44500  1.000 17.40000 ? 35  ARG D NE  1 
ATOM   3420 C CZ  . ARG D 1 34  ? -5.88500  29.28800  16.50900  1.000 25.36000 ? 35  ARG D CZ  1 
ATOM   3421 N NH1 . ARG D 1 34  ? -6.28200  28.96200  17.74800  1.000 21.35000 ? 35  ARG D NH1 1 
ATOM   3422 N NH2 . ARG D 1 34  ? -4.96900  30.22900  16.34100  1.000 23.87000 ? 35  ARG D NH2 1 
ATOM   3423 N N   . PHE D 1 35  ? -10.36800 26.49100  12.09900  1.000 9.54000  ? 36  PHE D N   1 
ATOM   3424 C CA  . PHE D 1 35  ? -10.82800 27.60400  11.30000  1.000 9.24000  ? 36  PHE D CA  1 
ATOM   3425 C C   . PHE D 1 35  ? -11.83600 28.35300  12.16700  1.000 9.53000  ? 36  PHE D C   1 
ATOM   3426 O O   . PHE D 1 35  ? -12.64900 27.72200  12.80900  1.000 8.90000  ? 36  PHE D O   1 
ATOM   3427 C CB  . PHE D 1 35  ? -11.52900 27.13100  10.02400  1.000 9.67000  ? 36  PHE D CB  1 
ATOM   3428 C CG  . PHE D 1 35  ? -12.13600 28.26500  9.22900   1.000 10.55000 ? 36  PHE D CG  1 
ATOM   3429 C CD1 . PHE D 1 35  ? -11.37400 28.92100  8.30200   1.000 12.63000 ? 36  PHE D CD1 1 
ATOM   3430 C CD2 . PHE D 1 35  ? -13.48100 28.65900  9.43800   1.000 12.10000 ? 36  PHE D CD2 1 
ATOM   3431 C CE1 . PHE D 1 35  ? -11.93300 29.93000  7.49500   1.000 10.13000 ? 36  PHE D CE1 1 
ATOM   3432 C CE2 . PHE D 1 35  ? -14.06800 29.68400  8.66100   1.000 11.78000 ? 36  PHE D CE2 1 
ATOM   3433 C CZ  . PHE D 1 35  ? -13.26900 30.31600  7.65500   1.000 10.01000 ? 36  PHE D CZ  1 
ATOM   3434 N N   . ASP D 1 36  ? -11.75700 29.66500  12.19900  1.000 8.21000  ? 37  ASP D N   1 
ATOM   3435 C CA  . ASP D 1 36  ? -12.67400 30.50000  12.97700  1.000 8.26000  ? 37  ASP D CA  1 
ATOM   3436 C C   . ASP D 1 36  ? -13.14100 31.60700  12.04200  1.000 12.39000 ? 37  ASP D C   1 
ATOM   3437 O O   . ASP D 1 36  ? -12.32000 32.45300  11.61900  1.000 11.28000 ? 37  ASP D O   1 
ATOM   3438 C CB  . ASP D 1 36  ? -11.96100 31.10200  14.19500  1.000 9.30000  ? 37  ASP D CB  1 
ATOM   3439 C CG  . ASP D 1 36  ? -12.90300 32.00000  15.07200  1.000 12.88000 ? 37  ASP D CG  1 
ATOM   3440 O OD1 . ASP D 1 36  ? -14.09100 32.20200  14.75200  1.000 12.73000 ? 37  ASP D OD1 1 
ATOM   3441 O OD2 . ASP D 1 36  ? -12.41400 32.50700  16.11800  1.000 20.56000 ? 37  ASP D OD2 1 
ATOM   3442 N N   . SER D 1 37  ? -14.44900 31.61600  11.72900  1.000 9.37000  ? 38  SER D N   1 
ATOM   3443 C CA  . SER D 1 37  ? -14.92300 32.61900  10.77500  1.000 10.60000 ? 38  SER D CA  1 
ATOM   3444 C C   . SER D 1 37  ? -14.83600 34.03400  11.31800  1.000 11.76000 ? 38  SER D C   1 
ATOM   3445 O O   . SER D 1 37  ? -14.93500 34.97600  10.51900  1.000 12.64000 ? 38  SER D O   1 
ATOM   3446 C CB  . SER D 1 37  ? -16.35700 32.34200  10.32000  1.000 12.96000 ? 38  SER D CB  1 
ATOM   3447 O OG  . SER D 1 37  ? -17.19300 32.46200  11.48600  1.000 12.21000 ? 38  SER D OG  1 
ATOM   3448 N N   . ASP D 1 38  ? -14.64500 34.21500  12.63200  1.000 8.76000  ? 39  ASP D N   1 
ATOM   3449 C CA  . ASP D 1 38  ? -14.51900 35.55300  13.20100  1.000 11.82000 ? 39  ASP D CA  1 
ATOM   3450 C C   . ASP D 1 38  ? -13.09800 36.12600  13.06200  1.000 16.31000 ? 39  ASP D C   1 
ATOM   3451 O O   . ASP D 1 38  ? -12.90900 37.32800  13.32000  1.000 14.14000 ? 39  ASP D O   1 
ATOM   3452 C CB  . ASP D 1 38  ? -14.91100 35.55800  14.66300  1.000 12.15000 ? 39  ASP D CB  1 
ATOM   3453 C CG  . ASP D 1 38  ? -16.39500 35.96900  14.89000  1.000 14.37000 ? 39  ASP D CG  1 
ATOM   3454 O OD1 . ASP D 1 38  ? -17.14400 36.11400  13.90600  1.000 12.29000 ? 39  ASP D OD1 1 
ATOM   3455 O OD2 . ASP D 1 38  ? -16.77900 36.10700  16.05700  1.000 13.04000 ? 39  ASP D OD2 1 
ATOM   3456 N N   . ALA D 1 39  ? -12.11600 35.32400  12.64400  1.000 15.41000 ? 40  ALA D N   1 
ATOM   3457 C CA  . ALA D 1 39  ? -10.73400 35.82000  12.61900  1.000 18.06000 ? 40  ALA D CA  1 
ATOM   3458 C C   . ALA D 1 39  ? -10.58700 36.96100  11.59400  1.000 20.98000 ? 40  ALA D C   1 
ATOM   3459 O O   . ALA D 1 39  ? -11.38200 37.10400  10.65700  1.000 20.06000 ? 40  ALA D O   1 
ATOM   3460 C CB  . ALA D 1 39  ? -9.75700  34.66600  12.29300  1.000 16.85000 ? 40  ALA D CB  1 
ATOM   3461 N N   . ALA D 1 40  ? -9.55000  37.80000  11.79400  1.000 26.21000 ? 41  ALA D N   1 
ATOM   3462 C CA  . ALA D 1 40  ? -9.33100  38.94600  10.88200  1.000 24.11000 ? 41  ALA D CA  1 
ATOM   3463 C C   . ALA D 1 40  ? -9.17200  38.51000  9.43200   1.000 31.42000 ? 41  ALA D C   1 
ATOM   3464 O O   . ALA D 1 40  ? -9.70800  39.12800  8.50800   1.000 28.51000 ? 41  ALA D O   1 
ATOM   3465 C CB  . ALA D 1 40  ? -8.09900  39.73500  11.33700  1.000 26.42000 ? 41  ALA D CB  1 
ATOM   3466 N N   . SER D 1 41  ? -8.44800  37.44500  9.17800   1.000 25.79000 ? 42  SER D N   1 
ATOM   3467 C CA  . SER D 1 41  ? -8.45700  36.94500  7.80700   1.000 32.36000 ? 42  SER D CA  1 
ATOM   3468 C C   . SER D 1 41  ? -8.66500  35.45900  7.99300   1.000 30.79000 ? 42  SER D C   1 
ATOM   3469 O O   . SER D 1 41  ? -7.71100  34.72900  8.28200   1.000 32.36000 ? 42  SER D O   1 
ATOM   3470 C CB  . SER D 1 41  ? -7.17400  37.30000  7.04800   1.000 32.35000 ? 42  SER D CB  1 
ATOM   3471 O OG  . SER D 1 41  ? -6.11500  36.53100  7.57100   1.000 49.81000 ? 42  SER D OG  1 
ATOM   3472 N N   . PRO D 1 42  ? -9.91400  35.00300  7.99600   1.000 25.29000 ? 43  PRO D N   1 
ATOM   3473 C CA  . PRO D 1 42  ? -10.16400 33.59800  8.35000   1.000 20.19000 ? 43  PRO D CA  1 
ATOM   3474 C C   . PRO D 1 42  ? -9.45300  32.66400  7.38500   1.000 19.36000 ? 43  PRO D C   1 
ATOM   3475 O O   . PRO D 1 42  ? -9.58700  32.77800  6.18000   1.000 17.36000 ? 43  PRO D O   1 
ATOM   3476 C CB  . PRO D 1 42  ? -11.69600 33.45600  8.25800   1.000 21.63000 ? 43  PRO D CB  1 
ATOM   3477 C CG  . PRO D 1 42  ? -12.23200 34.86300  8.27500   1.000 24.51000 ? 43  PRO D CG  1 
ATOM   3478 C CD  . PRO D 1 42  ? -11.13600 35.71000  7.60000   1.000 20.97000 ? 43  PRO D CD  1 
ATOM   3479 N N   . ARG D 1 43  ? -8.73000  31.70300  7.93800   1.000 15.16000 ? 44  ARG D N   1 
ATOM   3480 C CA  . ARG D 1 43  ? -7.98800  30.71900  7.15200   1.000 16.64000 ? 44  ARG D CA  1 
ATOM   3481 C C   . ARG D 1 43  ? -7.94000  29.38900  7.91200   1.000 10.99000 ? 44  ARG D C   1 
ATOM   3482 O O   . ARG D 1 43  ? -7.98000  29.35400  9.15200   1.000 14.39000 ? 44  ARG D O   1 
ATOM   3483 C CB  . ARG D 1 43  ? -6.53200  31.16100  6.89300   1.000 17.73000 ? 44  ARG D CB  1 
ATOM   3484 C CG  . ARG D 1 43  ? -6.36400  32.18500  5.76700   1.000 26.88000 ? 44  ARG D CG  1 
ATOM   3485 C CD  . ARG D 1 43  ? -4.89300  32.36500  5.39900   1.000 26.36000 ? 44  ARG D CD  1 
ATOM   3486 N NE  . ARG D 1 43  ? -4.31600  31.15600  4.82200   1.000 27.83000 ? 44  ARG D NE  1 
ATOM   3487 C CZ  . ARG D 1 43  ? -4.46600  30.79800  3.54900   1.000 20.90000 ? 44  ARG D CZ  1 
ATOM   3488 N NH1 . ARG D 1 43  ? -5.18500  31.51200  2.71200   1.000 25.22000 ? 44  ARG D NH1 1 
ATOM   3489 N NH2 . ARG D 1 43  ? -3.81600  29.74100  3.09200   1.000 24.84000 ? 44  ARG D NH2 1 
ATOM   3490 N N   . GLY D 1 44  ? -7.85700  28.30700  7.16700   1.000 10.73000 ? 45  GLY D N   1 
ATOM   3491 C CA  . GLY D 1 44  ? -7.55900  27.08100  7.86500   1.000 13.22000 ? 45  GLY D CA  1 
ATOM   3492 C C   . GLY D 1 44  ? -6.13500  27.24100  8.40000   1.000 15.70000 ? 45  GLY D C   1 
ATOM   3493 O O   . GLY D 1 44  ? -5.29200  27.72100  7.65100   1.000 12.50000 ? 45  GLY D O   1 
ATOM   3494 N N   . GLU D 1 45  ? -5.87800  26.90500  9.67200   1.000 13.50000 ? 46  GLU D N   1 
ATOM   3495 C CA  . GLU D 1 45  ? -4.57600  27.11500  10.34900  1.000 14.75000 ? 46  GLU D CA  1 
ATOM   3496 C C   . GLU D 1 45  ? -4.04400  25.80000  10.88800  1.000 13.52000 ? 46  GLU D C   1 
ATOM   3497 O O   . GLU D 1 45  ? -4.80900  25.03300  11.49000  1.000 10.63000 ? 46  GLU D O   1 
ATOM   3498 C CB  . GLU D 1 45  ? -4.70500  28.11900  11.52500  1.000 13.39000 ? 46  GLU D CB  1 
ATOM   3499 C CG  . GLU D 1 45  ? -4.99500  29.48600  11.04100  1.000 17.75000 ? 46  GLU D CG  1 
ATOM   3500 C CD  . GLU D 1 45  ? -5.15300  30.45000  12.20800  1.000 29.31000 ? 46  GLU D CD  1 
ATOM   3501 O OE1 . GLU D 1 45  ? -5.05300  29.99900  13.34500  1.000 27.96000 ? 46  GLU D OE1 1 
ATOM   3502 O OE2 . GLU D 1 45  ? -5.29800  31.66400  11.98300  1.000 34.74000 ? 46  GLU D OE2 1 
ATOM   3503 N N   . PRO D 1 46  ? -2.73200  25.52500  10.71700  1.000 12.77000 ? 47  PRO D N   1 
ATOM   3504 C CA  . PRO D 1 46  ? -2.16100  24.28500  11.25300  1.000 13.63000 ? 47  PRO D CA  1 
ATOM   3505 C C   . PRO D 1 46  ? -2.13500  24.31000  12.76100  1.000 14.10000 ? 47  PRO D C   1 
ATOM   3506 O O   . PRO D 1 46  ? -1.96700  25.36800  13.36700  1.000 14.42000 ? 47  PRO D O   1 
ATOM   3507 C CB  . PRO D 1 46  ? -0.74400  24.25800  10.65300  1.000 17.38000 ? 47  PRO D CB  1 
ATOM   3508 C CG  . PRO D 1 46  ? -0.42700  25.79100  10.35700  1.000 13.45000 ? 47  PRO D CG  1 
ATOM   3509 C CD  . PRO D 1 46  ? -1.76700  26.32700  9.91500   1.000 14.44000 ? 47  PRO D CD  1 
ATOM   3510 N N   . ARG D 1 47  ? -2.41800  23.15800  13.37600  1.000 12.05000 ? 48  ARG D N   1 
ATOM   3511 C CA  . ARG D 1 47  ? -2.34100  23.05000  14.83800  1.000 14.62000 ? 48  ARG D CA  1 
ATOM   3512 C C   . ARG D 1 47  ? -1.44500  21.89600  15.27000  1.000 18.09000 ? 48  ARG D C   1 
ATOM   3513 O O   . ARG D 1 47  ? -1.29800  21.65800  16.48400  1.000 17.46000 ? 48  ARG D O   1 
ATOM   3514 C CB  . ARG D 1 47  ? -3.76200  22.88500  15.44600  1.000 13.86000 ? 48  ARG D CB  1 
ATOM   3515 C CG  . ARG D 1 47  ? -4.65100  24.12000  15.21900  1.000 14.99000 ? 48  ARG D CG  1 
ATOM   3516 C CD  . ARG D 1 47  ? -4.16700  25.33300  15.98600  1.000 16.83000 ? 48  ARG D CD  1 
ATOM   3517 N NE  . ARG D 1 47  ? -4.82600  25.35400  17.30100  1.000 29.23000 ? 48  ARG D NE  1 
ATOM   3518 C CZ  . ARG D 1 47  ? -4.42900  26.14400  18.29700  1.000 33.14000 ? 48  ARG D CZ  1 
ATOM   3519 N NH1 . ARG D 1 47  ? -3.34900  26.92600  18.16200  1.000 22.64000 ? 48  ARG D NH1 1 
ATOM   3520 N NH2 . ARG D 1 47  ? -5.11300  26.13900  19.45500  1.000 19.58000 ? 48  ARG D NH2 1 
ATOM   3521 N N   . ALA D 1 48  ? -0.80300  21.20400  14.31700  1.000 13.14000 ? 49  ALA D N   1 
ATOM   3522 C CA  . ALA D 1 48  ? 0.14500   20.14100  14.61000  1.000 13.31000 ? 49  ALA D CA  1 
ATOM   3523 C C   . ALA D 1 48  ? 1.30200   20.35400  13.64900  1.000 16.82000 ? 49  ALA D C   1 
ATOM   3524 O O   . ALA D 1 48  ? 1.10300   20.83000  12.51700  1.000 16.02000 ? 49  ALA D O   1 
ATOM   3525 C CB  . ALA D 1 48  ? -0.43600  18.72000  14.41800  1.000 10.91000 ? 49  ALA D CB  1 
ATOM   3526 N N   . PRO D 1 49  ? 2.52000   19.99800  14.05600  1.000 19.24000 ? 50  PRO D N   1 
ATOM   3527 C CA  . PRO D 1 49  ? 3.67400   20.25400  13.16900  1.000 16.28000 ? 50  PRO D CA  1 
ATOM   3528 C C   . PRO D 1 49  ? 3.64700   19.42400  11.89100  1.000 18.67000 ? 50  PRO D C   1 
ATOM   3529 O O   . PRO D 1 49  ? 4.20200   19.83700  10.85700  1.000 16.05000 ? 50  PRO D O   1 
ATOM   3530 C CB  . PRO D 1 49  ? 4.88700   19.86100  14.04900  1.000 19.10000 ? 50  PRO D CB  1 
ATOM   3531 C CG  . PRO D 1 49  ? 4.40800   19.82200  15.41500  1.000 26.07000 ? 50  PRO D CG  1 
ATOM   3532 C CD  . PRO D 1 49  ? 2.93200   19.43000  15.35400  1.000 22.76000 ? 50  PRO D CD  1 
ATOM   3533 N N   . TRP D 1 50  ? 2.98600   18.27300  11.90000  1.000 16.83000 ? 51  TRP D N   1 
ATOM   3534 C CA  . TRP D 1 50  ? 3.04100   17.41000  10.73500  1.000 17.85000 ? 51  TRP D CA  1 
ATOM   3535 C C   . TRP D 1 50  ? 2.06400   17.80600  9.60900   1.000 19.33000 ? 51  TRP D C   1 
ATOM   3536 O O   . TRP D 1 50  ? 1.92800   17.03400  8.65200   1.000 22.30000 ? 51  TRP D O   1 
ATOM   3537 C CB  . TRP D 1 50  ? 2.79600   15.93800  11.15100  1.000 16.80000 ? 51  TRP D CB  1 
ATOM   3538 C CG  . TRP D 1 50  ? 1.70900   15.71700  12.22100  1.000 16.08000 ? 51  TRP D CG  1 
ATOM   3539 C CD1 . TRP D 1 50  ? 1.89000   15.59800  13.56500  1.000 16.88000 ? 51  TRP D CD1 1 
ATOM   3540 C CD2 . TRP D 1 50  ? 0.30600   15.62800  11.99700  1.000 17.56000 ? 51  TRP D CD2 1 
ATOM   3541 N NE1 . TRP D 1 50  ? 0.67900   15.42000  14.21200  1.000 14.90000 ? 51  TRP D NE1 1 
ATOM   3542 C CE2 . TRP D 1 50  ? -0.31400  15.45600  13.26700  1.000 15.92000 ? 51  TRP D CE2 1 
ATOM   3543 C CE3 . TRP D 1 50  ? -0.49500  15.65900  10.84700  1.000 16.93000 ? 51  TRP D CE3 1 
ATOM   3544 C CZ2 . TRP D 1 50  ? -1.66900  15.31600  13.41000  1.000 13.97000 ? 51  TRP D CZ2 1 
ATOM   3545 C CZ3 . TRP D 1 50  ? -1.88200  15.53700  11.00800  1.000 12.77000 ? 51  TRP D CZ3 1 
ATOM   3546 C CH2 . TRP D 1 50  ? -2.43300  15.34100  12.24500  1.000 13.69000 ? 51  TRP D CH2 1 
ATOM   3547 N N   . VAL D 1 51  ? 1.36500   18.93800  9.69300   1.000 15.82000 ? 52  VAL D N   1 
ATOM   3548 C CA  . VAL D 1 51  ? 0.70100   19.53800  8.53600   1.000 16.51000 ? 52  VAL D CA  1 
ATOM   3549 C C   . VAL D 1 51  ? 1.28400   20.90900  8.20800   1.000 15.66000 ? 52  VAL D C   1 
ATOM   3550 O O   . VAL D 1 51  ? 0.79000   21.56700  7.30100   1.000 15.86000 ? 52  VAL D O   1 
ATOM   3551 C CB  . VAL D 1 51  ? -0.83900  19.67400  8.70900   1.000 16.57000 ? 52  VAL D CB  1 
ATOM   3552 C CG1 . VAL D 1 51  ? -1.52100  18.34900  8.68900   1.000 16.74000 ? 52  VAL D CG1 1 
ATOM   3553 C CG2 . VAL D 1 51  ? -1.19900  20.48400  9.97900   1.000 13.53000 ? 52  VAL D CG2 1 
ATOM   3554 N N   . GLU D 1 52  ? 2.26500   21.39700  8.98000   1.000 16.85000 ? 53  GLU D N   1 
ATOM   3555 C CA  . GLU D 1 52  ? 2.83000   22.72600  8.73500   1.000 17.87000 ? 53  GLU D CA  1 
ATOM   3556 C C   . GLU D 1 52  ? 3.58000   22.80200  7.43100   1.000 23.58000 ? 53  GLU D C   1 
ATOM   3557 O O   . GLU D 1 52  ? 3.71300   23.89200  6.87300   1.000 28.64000 ? 53  GLU D O   1 
ATOM   3558 C CB  . GLU D 1 52  ? 3.78100   23.16000  9.84900   1.000 19.52000 ? 53  GLU D CB  1 
ATOM   3559 C CG  . GLU D 1 52  ? 3.01800   23.39600  11.12200  1.000 18.58000 ? 53  GLU D CG  1 
ATOM   3560 C CD  . GLU D 1 52  ? 3.88800   23.89700  12.22600  1.000 33.74000 ? 53  GLU D CD  1 
ATOM   3561 O OE1 . GLU D 1 52  ? 5.10900   23.91900  12.02900  1.000 40.36000 ? 53  GLU D OE1 1 
ATOM   3562 O OE2 . GLU D 1 52  ? 3.35200   24.19700  13.30300  1.000 37.80000 ? 53  GLU D OE2 1 
ATOM   3563 N N   . GLN D 1 53  ? 4.00000   21.69500  6.91300   1.000 15.88000 ? 54  GLN D N   1 
ATOM   3564 C CA  . GLN D 1 53  ? 4.72300   21.67600  5.68000   1.000 21.18000 ? 54  GLN D CA  1 
ATOM   3565 C C   . GLN D 1 53  ? 3.86800   21.42300  4.45100   1.000 22.97000 ? 54  GLN D C   1 
ATOM   3566 O O   . GLN D 1 53  ? 4.37600   21.33700  3.40100   1.000 21.84000 ? 54  GLN D O   1 
ATOM   3567 C CB  . GLN D 1 53  ? 5.73800   20.57900  5.76900   1.000 21.37000 ? 54  GLN D CB  1 
ATOM   3568 C CG  . GLN D 1 53  ? 5.19900   19.24500  5.35800   1.000 39.10000 ? 54  GLN D CG  1 
ATOM   3569 C CD  . GLN D 1 53  ? 3.98800   18.69900  6.10600   1.000 35.11000 ? 54  GLN D CD  1 
ATOM   3570 O OE1 . GLN D 1 53  ? 3.49600   19.23600  7.05400   1.000 31.57000 ? 54  GLN D OE1 1 
ATOM   3571 N NE2 . GLN D 1 53  ? 3.56000   17.58900  5.65500   1.000 44.44000 ? 54  GLN D NE2 1 
ATOM   3572 N N   . GLU D 1 54  ? 2.57000   21.27700  4.61200   1.000 16.62000 ? 55  GLU D N   1 
ATOM   3573 C CA  . GLU D 1 54  ? 1.71400   21.02600  3.49000   1.000 17.03000 ? 55  GLU D CA  1 
ATOM   3574 C C   . GLU D 1 54  ? 1.72800   21.97800  2.29200   1.000 20.97000 ? 55  GLU D C   1 
ATOM   3575 O O   . GLU D 1 54  ? 1.40200   21.56000  1.21600   1.000 32.81000 ? 55  GLU D O   1 
ATOM   3576 C CB  . GLU D 1 54  ? 0.28500   20.71300  3.91500   1.000 16.17000 ? 55  GLU D CB  1 
ATOM   3577 C CG  . GLU D 1 54  ? 0.11500   19.36200  4.52100   1.000 14.65000 ? 55  GLU D CG  1 
ATOM   3578 C CD  . GLU D 1 54  ? 0.49000   18.24500  3.58600   1.000 25.49000 ? 55  GLU D CD  1 
ATOM   3579 O OE1 . GLU D 1 54  ? 0.56200   18.43000  2.40000   1.000 26.05000 ? 55  GLU D OE1 1 
ATOM   3580 O OE2 . GLU D 1 54  ? 0.71300   17.19900  4.03400   1.000 27.36000 ? 55  GLU D OE2 1 
ATOM   3581 N N   . GLY D 1 55  ? 2.02300   23.22200  2.46000   1.000 20.55000 ? 56  GLY D N   1 
ATOM   3582 C CA  . GLY D 1 55  ? 2.06300   24.09000  1.29900   1.000 17.20000 ? 56  GLY D CA  1 
ATOM   3583 C C   . GLY D 1 55  ? 0.93100   25.05800  1.18600   1.000 16.73000 ? 56  GLY D C   1 
ATOM   3584 O O   . GLY D 1 55  ? -0.13600  24.72200  1.52900   1.000 15.71000 ? 56  GLY D O   1 
ATOM   3585 N N   . PRO D 1 56  ? 1.19000   26.24000  0.63100   1.000 15.12000 ? 57  PRO D N   1 
ATOM   3586 C CA  . PRO D 1 56  ? 0.13000   27.24100  0.51300   1.000 16.81000 ? 57  PRO D CA  1 
ATOM   3587 C C   . PRO D 1 56  ? -1.06700  26.80400  -0.31500  1.000 13.62000 ? 57  PRO D C   1 
ATOM   3588 O O   . PRO D 1 56  ? -2.14300  27.16900  0.01800   1.000 13.57000 ? 57  PRO D O   1 
ATOM   3589 C CB  . PRO D 1 56  ? 0.81900   28.43200  -0.13600  1.000 18.42000 ? 57  PRO D CB  1 
ATOM   3590 C CG  . PRO D 1 56  ? 2.29100   28.20600  0.07300   1.000 20.03000 ? 57  PRO D CG  1 
ATOM   3591 C CD  . PRO D 1 56  ? 2.45800   26.71700  0.09200   1.000 19.70000 ? 57  PRO D CD  1 
ATOM   3592 N N   . GLU D 1 57  ? -0.85000  26.08500  -1.38800  1.000 14.07000 ? 58  GLU D N   1 
ATOM   3593 C CA  . GLU D 1 57  ? -1.97700  25.61100  -2.19300  1.000 14.44000 ? 58  GLU D CA  1 
ATOM   3594 C C   . GLU D 1 57  ? -2.89400  24.71700  -1.36200  1.000 17.93000 ? 58  GLU D C   1 
ATOM   3595 O O   . GLU D 1 57  ? -4.13700  24.85600  -1.40300  1.000 13.51000 ? 58  GLU D O   1 
ATOM   3596 C CB  . GLU D 1 57  ? -1.49000  24.82700  -3.43600  1.000 20.10000 ? 58  GLU D CB  1 
ATOM   3597 C CG  . GLU D 1 57  ? -1.10000  25.75100  -4.61600  1.000 30.88000 ? 58  GLU D CG  1 
ATOM   3598 C CD  . GLU D 1 57  ? -1.38100  25.13600  -6.05500  1.000 41.38000 ? 58  GLU D CD  1 
ATOM   3599 O OE1 . GLU D 1 57  ? -0.98200  23.98500  -6.29300  1.000 30.70000 ? 58  GLU D OE1 1 
ATOM   3600 O OE2 . GLU D 1 57  ? -1.99400  25.82400  -6.93300  1.000 45.18000 ? 58  GLU D OE2 1 
ATOM   3601 N N   . TYR D 1 58  ? -2.30000  23.82300  -0.56400  1.000 11.98000 ? 59  TYR D N   1 
ATOM   3602 C CA  . TYR D 1 58  ? -3.10800  23.00500  0.35400   1.000 14.08000 ? 59  TYR D CA  1 
ATOM   3603 C C   . TYR D 1 58  ? -3.90500  23.87500  1.31000   1.000 12.91000 ? 59  TYR D C   1 
ATOM   3604 O O   . TYR D 1 58  ? -5.12300  23.67800  1.50300   1.000 13.56000 ? 59  TYR D O   1 
ATOM   3605 C CB  . TYR D 1 58  ? -2.17800  22.07100  1.13900   1.000 12.23000 ? 59  TYR D CB  1 
ATOM   3606 C CG  . TYR D 1 58  ? -2.82300  21.37000  2.31600   1.000 12.45000 ? 59  TYR D CG  1 
ATOM   3607 C CD1 . TYR D 1 58  ? -2.88900  21.99100  3.58200   1.000 10.58000 ? 59  TYR D CD1 1 
ATOM   3608 C CD2 . TYR D 1 58  ? -3.24600  20.05900  2.20400   1.000 11.79000 ? 59  TYR D CD2 1 
ATOM   3609 C CE1 . TYR D 1 58  ? -3.43000  21.34000  4.65600   1.000 12.48000 ? 59  TYR D CE1 1 
ATOM   3610 C CE2 . TYR D 1 58  ? -3.80900  19.38500  3.31300   1.000 14.98000 ? 59  TYR D CE2 1 
ATOM   3611 C CZ  . TYR D 1 58  ? -3.90500  20.05100  4.53600   1.000 11.84000 ? 59  TYR D CZ  1 
ATOM   3612 O OH  . TYR D 1 58  ? -4.41800  19.36000  5.63200   1.000 14.75000 ? 59  TYR D OH  1 
ATOM   3613 N N   . TRP D 1 59  ? -3.23500  24.85300  1.93900   1.000 12.73000 ? 60  TRP D N   1 
ATOM   3614 C CA  . TRP D 1 59  ? -3.93500  25.63300  2.96800   1.000 13.19000 ? 60  TRP D CA  1 
ATOM   3615 C C   . TRP D 1 59  ? -4.96500  26.55600  2.33400   1.000 16.59000 ? 60  TRP D C   1 
ATOM   3616 O O   . TRP D 1 59  ? -6.01800  26.76500  2.90700   1.000 14.31000 ? 60  TRP D O   1 
ATOM   3617 C CB  . TRP D 1 59  ? -2.92100  26.42300  3.83700   1.000 11.50000 ? 60  TRP D CB  1 
ATOM   3618 C CG  . TRP D 1 59  ? -2.23900  25.49600  4.78800   1.000 14.57000 ? 60  TRP D CG  1 
ATOM   3619 C CD1 . TRP D 1 59  ? -0.94300  25.01100  4.72800   1.000 14.51000 ? 60  TRP D CD1 1 
ATOM   3620 C CD2 . TRP D 1 59  ? -2.85300  24.86200  5.91500   1.000 14.72000 ? 60  TRP D CD2 1 
ATOM   3621 N NE1 . TRP D 1 59  ? -0.73900  24.12100  5.75800   1.000 12.16000 ? 60  TRP D NE1 1 
ATOM   3622 C CE2 . TRP D 1 59  ? -1.87600  24.03000  6.51400   1.000 15.19000 ? 60  TRP D CE2 1 
ATOM   3623 C CE3 . TRP D 1 59  ? -4.15900  24.93100  6.47700   1.000 15.82000 ? 60  TRP D CE3 1 
ATOM   3624 C CZ2 . TRP D 1 59  ? -2.14000  23.24300  7.64300   1.000 13.82000 ? 60  TRP D CZ2 1 
ATOM   3625 C CZ3 . TRP D 1 59  ? -4.44200  24.19100  7.58300   1.000 11.02000 ? 60  TRP D CZ3 1 
ATOM   3626 C CH2 . TRP D 1 59  ? -3.42800  23.32500  8.17500   1.000 16.15000 ? 60  TRP D CH2 1 
ATOM   3627 N N   . ASP D 1 60  ? -4.70700  27.06900  1.11900   1.000 12.86000 ? 61  ASP D N   1 
ATOM   3628 C CA  . ASP D 1 60  ? -5.70200  27.89300  0.42800   1.000 16.69000 ? 61  ASP D CA  1 
ATOM   3629 C C   . ASP D 1 60  ? -6.96100  27.09300  0.13300   1.000 14.94000 ? 61  ASP D C   1 
ATOM   3630 O O   . ASP D 1 60  ? -8.09200  27.59400  0.23600   1.000 17.76000 ? 61  ASP D O   1 
ATOM   3631 C CB  . ASP D 1 60  ? -5.13100  28.38600  -0.90800  1.000 14.19000 ? 61  ASP D CB  1 
ATOM   3632 C CG  . ASP D 1 60  ? -4.17500  29.55000  -0.76300  1.000 15.97000 ? 61  ASP D CG  1 
ATOM   3633 O OD1 . ASP D 1 60  ? -3.96000  30.08100  0.35700   1.000 15.24000 ? 61  ASP D OD1 1 
ATOM   3634 O OD2 . ASP D 1 60  ? -3.56800  29.87700  -1.80500  1.000 18.90000 ? 61  ASP D OD2 1 
ATOM   3635 N N   . ARG D 1 61  ? -6.78000  25.87300  -0.27800  1.000 12.99000 ? 62  ARG D N   1 
ATOM   3636 C CA  . ARG D 1 61  ? -7.87600  25.00400  -0.61500  1.000 17.83000 ? 62  ARG D CA  1 
ATOM   3637 C C   . ARG D 1 61  ? -8.74700  24.69100  0.62300   1.000 14.20000 ? 62  ARG D C   1 
ATOM   3638 O O   . ARG D 1 61  ? -9.93900  24.71400  0.58100   1.000 12.50000 ? 62  ARG D O   1 
ATOM   3639 C CB  . ARG D 1 61  ? -7.34000  23.74900  -1.24100  1.000 17.44000 ? 62  ARG D CB  1 
ATOM   3640 C CG  . ARG D 1 61  ? -8.36200  22.93300  -1.92600  1.000 23.78000 ? 62  ARG D CG  1 
ATOM   3641 C CD  . ARG D 1 61  ? -8.33900  21.54500  -1.39100  1.000 41.35000 ? 62  ARG D CD  1 
ATOM   3642 N NE  . ARG D 1 61  ? -7.57400  20.62900  -2.19900  1.000 55.75000 ? 62  ARG D NE  1 
ATOM   3643 C CZ  . ARG D 1 61  ? -8.04300  19.49000  -2.69100  1.000 37.99000 ? 62  ARG D CZ  1 
ATOM   3644 N NH1 . ARG D 1 61  ? -9.29600  19.12800  -2.45000  0.000 39.51000 ? 62  ARG D NH1 1 
ATOM   3645 N NH2 . ARG D 1 61  ? -7.26200  18.71100  -3.42500  0.000 34.57000 ? 62  ARG D NH2 1 
ATOM   3646 N N   . GLU D 1 62  ? -8.09000  24.32500  1.70300   1.000 11.79000 ? 63  GLU D N   1 
ATOM   3647 C CA  . GLU D 1 62  ? -8.85100  24.11400  2.94700   1.000 12.42000 ? 63  GLU D CA  1 
ATOM   3648 C C   . GLU D 1 62  ? -9.57100  25.39600  3.35200   1.000 11.95000 ? 63  GLU D C   1 
ATOM   3649 O O   . GLU D 1 62  ? -10.76200 25.37300  3.72900   1.000 12.44000 ? 63  GLU D O   1 
ATOM   3650 C CB  . GLU D 1 62  ? -7.93500  23.64300  4.08000   1.000 11.64000 ? 63  GLU D CB  1 
ATOM   3651 C CG  . GLU D 1 62  ? -7.25500  22.27900  3.80100   1.000 10.05000 ? 63  GLU D CG  1 
ATOM   3652 C CD  . GLU D 1 62  ? -8.27200  21.20400  3.37900   1.000 11.20000 ? 63  GLU D CD  1 
ATOM   3653 O OE1 . GLU D 1 62  ? -8.96700  20.72800  4.28500   1.000 10.16000 ? 63  GLU D OE1 1 
ATOM   3654 O OE2 . GLU D 1 62  ? -8.39300  20.84800  2.18600   1.000 12.19000 ? 63  GLU D OE2 1 
ATOM   3655 N N   . THR D 1 63  ? -8.85000  26.52700  3.33900   1.000 10.27000 ? 64  THR D N   1 
ATOM   3656 C CA  . THR D 1 63  ? -9.49100  27.82100  3.64100   1.000 12.75000 ? 64  THR D CA  1 
ATOM   3657 C C   . THR D 1 63  ? -10.76000 28.05700  2.82200   1.000 13.40000 ? 64  THR D C   1 
ATOM   3658 O O   . THR D 1 63  ? -11.77200 28.50600  3.36000   1.000 12.40000 ? 64  THR D O   1 
ATOM   3659 C CB  . THR D 1 63  ? -8.46400  28.94600  3.41000   1.000 13.66000 ? 64  THR D CB  1 
ATOM   3660 O OG1 . THR D 1 63  ? -7.46700  28.78200  4.42300   1.000 13.54000 ? 64  THR D OG1 1 
ATOM   3661 C CG2 . THR D 1 63  ? -9.11000  30.34400  3.50100   1.000 14.22000 ? 64  THR D CG2 1 
ATOM   3662 N N   . GLN D 1 64  ? -10.71600 27.77700  1.51600   1.000 11.68000 ? 65  GLN D N   1 
ATOM   3663 C CA  . GLN D 1 64  ? -11.87400 28.03100  0.65900   1.000 16.50000 ? 65  GLN D CA  1 
ATOM   3664 C C   . GLN D 1 64  ? -13.07600 27.17100  1.09100   1.000 14.25000 ? 65  GLN D C   1 
ATOM   3665 O O   . GLN D 1 64  ? -14.23900 27.61500  1.05300   1.000 12.74000 ? 65  GLN D O   1 
ATOM   3666 C CB  . GLN D 1 64  ? -11.46700 27.72800  -0.79400  1.000 20.08000 ? 65  GLN D CB  1 
ATOM   3667 C CG  . GLN D 1 64  ? -12.46100 28.10500  -1.97600  1.000 30.27000 ? 65  GLN D CG  1 
ATOM   3668 C CD  . GLN D 1 64  ? -11.88000 27.65200  -3.40600  1.000 47.07000 ? 65  GLN D CD  1 
ATOM   3669 O OE1 . GLN D 1 64  ? -10.98300 26.77000  -3.52300  1.000 46.64000 ? 65  GLN D OE1 1 
ATOM   3670 N NE2 . GLN D 1 64  ? -12.35800 28.29600  -4.45400  1.000 37.71000 ? 65  GLN D NE2 1 
ATOM   3671 N N   . LYS D 1 65  ? -12.82000 25.89400  1.37600   1.000 13.14000 ? 66  LYS D N   1 
ATOM   3672 C CA  . LYS D 1 65  ? -13.87100 24.99800  1.86500   1.000 14.23000 ? 66  LYS D CA  1 
ATOM   3673 C C   . LYS D 1 65  ? -14.53400 25.57400  3.10000   1.000 13.26000 ? 66  LYS D C   1 
ATOM   3674 O O   . LYS D 1 65  ? -15.76600 25.58600  3.18200   1.000 11.35000 ? 66  LYS D O   1 
ATOM   3675 C CB  . LYS D 1 65  ? -13.29600 23.59200  2.15900   1.000 14.46000 ? 66  LYS D CB  1 
ATOM   3676 C CG  . LYS D 1 65  ? -12.90800 22.77400  0.91100   1.000 16.27000 ? 66  LYS D CG  1 
ATOM   3677 C CD  . LYS D 1 65  ? -12.00000 21.58000  1.44700   1.000 20.34000 ? 66  LYS D CD  1 
ATOM   3678 C CE  . LYS D 1 65  ? -11.50600 20.65700  0.42600   1.000 20.76000 ? 66  LYS D CE  1 
ATOM   3679 N NZ  . LYS D 1 65  ? -10.57500 19.72000  1.15000   1.000 13.16000 ? 66  LYS D NZ  1 
ATOM   3680 N N   . TYR D 1 66  ? -13.73300 25.95900  4.11900   1.000 13.00000 ? 67  TYR D N   1 
ATOM   3681 C CA  . TYR D 1 66  ? -14.31100 26.47400  5.37300   1.000 13.27000 ? 67  TYR D CA  1 
ATOM   3682 C C   . TYR D 1 66  ? -15.08600 27.76400  5.15000   1.000 12.13000 ? 67  TYR D C   1 
ATOM   3683 O O   . TYR D 1 66  ? -16.11900 27.98100  5.77000   1.000 12.25000 ? 67  TYR D O   1 
ATOM   3684 C CB  . TYR D 1 66  ? -13.19000 26.74200  6.39400   1.000 10.33000 ? 67  TYR D CB  1 
ATOM   3685 C CG  . TYR D 1 66  ? -12.50300 25.46400  6.84800   1.000 9.09000  ? 67  TYR D CG  1 
ATOM   3686 C CD1 . TYR D 1 66  ? -13.24800 24.33900  7.21000   1.000 11.23000 ? 67  TYR D CD1 1 
ATOM   3687 C CD2 . TYR D 1 66  ? -11.11300 25.40000  6.94500   1.000 9.69000  ? 67  TYR D CD2 1 
ATOM   3688 C CE1 . TYR D 1 66  ? -12.62000 23.14700  7.65100   1.000 13.44000 ? 67  TYR D CE1 1 
ATOM   3689 C CE2 . TYR D 1 66  ? -10.47800 24.21500  7.36600   1.000 12.08000 ? 67  TYR D CE2 1 
ATOM   3690 C CZ  . TYR D 1 66  ? -11.21300 23.11300  7.71000   1.000 11.01000 ? 67  TYR D CZ  1 
ATOM   3691 O OH  . TYR D 1 66  ? -10.54300 21.98400  8.12100   1.000 10.73000 ? 67  TYR D OH  1 
ATOM   3692 N N   . LYS D 1 67  ? -14.55400 28.68100  4.34000   1.000 12.39000 ? 68  LYS D N   1 
ATOM   3693 C CA  . LYS D 1 67  ? -15.27000 29.93800  4.11200   1.000 13.04000 ? 68  LYS D CA  1 
ATOM   3694 C C   . LYS D 1 67  ? -16.58500 29.66000  3.43200   1.000 14.07000 ? 68  LYS D C   1 
ATOM   3695 O O   . LYS D 1 67  ? -17.58800 30.29300  3.74200   1.000 13.79000 ? 68  LYS D O   1 
ATOM   3696 C CB  . LYS D 1 67  ? -14.46100 30.84200  3.18900   1.000 13.07000 ? 68  LYS D CB  1 
ATOM   3697 C CG  . LYS D 1 67  ? -13.18300 31.25300  3.81900   1.000 19.43000 ? 68  LYS D CG  1 
ATOM   3698 C CD  . LYS D 1 67  ? -12.60800 32.50900  3.14000   1.000 33.90000 ? 68  LYS D CD  1 
ATOM   3699 C CE  . LYS D 1 67  ? -11.85600 33.37500  4.14300   1.000 34.45000 ? 68  LYS D CE  1 
ATOM   3700 N NZ  . LYS D 1 67  ? -10.96200 34.24900  3.28600   1.000 39.60000 ? 68  LYS D NZ  1 
ATOM   3701 N N   . ARG D 1 68  ? -16.56100 28.80300  2.40100   1.000 13.91000 ? 69  ARG D N   1 
ATOM   3702 C CA  . ARG D 1 68  ? -17.81200 28.47100  1.71100   1.000 14.20000 ? 69  ARG D CA  1 
ATOM   3703 C C   . ARG D 1 68  ? -18.76200 27.72600  2.64600   1.000 14.16000 ? 69  ARG D C   1 
ATOM   3704 O O   . ARG D 1 68  ? -19.98900 27.90200  2.58200   1.000 13.26000 ? 69  ARG D O   1 
ATOM   3705 C CB  . ARG D 1 68  ? -17.52200 27.60800  0.47700   1.000 17.69000 ? 69  ARG D CB  1 
ATOM   3706 C CG  . ARG D 1 68  ? -16.78800 28.35500  -0.64200  1.000 16.51000 ? 69  ARG D CG  1 
ATOM   3707 C CD  . ARG D 1 68  ? -16.77900 27.57500  -1.94900  1.000 25.87000 ? 69  ARG D CD  1 
ATOM   3708 N NE  . ARG D 1 68  ? -17.91400 27.90900  -2.81900  1.000 49.78000 ? 69  ARG D NE  1 
ATOM   3709 C CZ  . ARG D 1 68  ? -18.49500 27.07600  -3.68600  1.000 43.69000 ? 69  ARG D CZ  1 
ATOM   3710 N NH1 . ARG D 1 68  ? -17.98800 25.87700  -3.93900  1.000 42.30000 ? 69  ARG D NH1 1 
ATOM   3711 N NH2 . ARG D 1 68  ? -19.61400 27.45500  -4.31500  1.000 41.84000 ? 69  ARG D NH2 1 
ATOM   3712 N N   . GLN D 1 69  ? -18.23200 26.84300  3.47600   1.000 12.93000 ? 70  GLN D N   1 
ATOM   3713 C CA  . GLN D 1 69  ? -19.11200 26.13500  4.40900   1.000 14.15000 ? 70  GLN D CA  1 
ATOM   3714 C C   . GLN D 1 69  ? -19.71200 27.08700  5.42500   1.000 15.11000 ? 70  GLN D C   1 
ATOM   3715 O O   . GLN D 1 69  ? -20.88700 26.94700  5.82200   1.000 12.51000 ? 70  GLN D O   1 
ATOM   3716 C CB  . GLN D 1 69  ? -18.32900 24.99800  5.11700   1.000 12.02000 ? 70  GLN D CB  1 
ATOM   3717 C CG  . GLN D 1 69  ? -19.27600 24.00900  5.88300   1.000 12.99000 ? 70  GLN D CG  1 
ATOM   3718 C CD  . GLN D 1 69  ? -20.31300 23.41500  4.92600   1.000 18.81000 ? 70  GLN D CD  1 
ATOM   3719 O OE1 . GLN D 1 69  ? -19.97700 22.78300  3.90400   1.000 15.31000 ? 70  GLN D OE1 1 
ATOM   3720 N NE2 . GLN D 1 69  ? -21.58700 23.64400  5.23300   1.000 12.78000 ? 70  GLN D NE2 1 
ATOM   3721 N N   . ALA D 1 70  ? -18.91000 28.02600  5.94300   1.000 11.24000 ? 71  ALA D N   1 
ATOM   3722 C CA  . ALA D 1 70  ? -19.47100 28.99000  6.88700   1.000 11.34000 ? 71  ALA D CA  1 
ATOM   3723 C C   . ALA D 1 70  ? -20.65000 29.73600  6.25700   1.000 17.44000 ? 71  ALA D C   1 
ATOM   3724 O O   . ALA D 1 70  ? -21.67100 29.99500  6.90900   1.000 12.32000 ? 71  ALA D O   1 
ATOM   3725 C CB  . ALA D 1 70  ? -18.37600 30.00500  7.33000   1.000 10.12000 ? 71  ALA D CB  1 
ATOM   3726 N N   . GLN D 1 71  ? -20.50300 30.16000  5.00100   1.000 13.45000 ? 72  GLN D N   1 
ATOM   3727 C CA  . GLN D 1 71  ? -21.60600 30.87100  4.36400   1.000 11.53000 ? 72  GLN D CA  1 
ATOM   3728 C C   . GLN D 1 71  ? -22.80700 29.96200  4.21500   1.000 13.30000 ? 72  GLN D C   1 
ATOM   3729 O O   . GLN D 1 71  ? -23.94200 30.39600  4.44700   1.000 14.00000 ? 72  GLN D O   1 
ATOM   3730 C CB  . GLN D 1 71  ? -21.22100 31.44300  2.97200   1.000 12.82000 ? 72  GLN D CB  1 
ATOM   3731 C CG  . GLN D 1 71  ? -19.94400 32.28100  2.96600   1.000 18.57000 ? 72  GLN D CG  1 
ATOM   3732 C CD  . GLN D 1 71  ? -19.53900 32.78000  1.52700   1.000 38.90000 ? 72  GLN D CD  1 
ATOM   3733 O OE1 . GLN D 1 71  ? -19.46600 31.99100  0.57100   1.000 39.77000 ? 72  GLN D OE1 1 
ATOM   3734 N NE2 . GLN D 1 71  ? -19.21000 34.06200  1.40800   1.000 38.78000 ? 72  GLN D NE2 1 
ATOM   3735 N N   . ALA D 1 72  ? -22.57600 28.69600  3.86900   1.000 11.75000 ? 73  ALA D N   1 
ATOM   3736 C CA  . ALA D 1 72  ? -23.70300 27.74800  3.73500   1.000 12.38000 ? 73  ALA D CA  1 
ATOM   3737 C C   . ALA D 1 72  ? -24.39800 27.50600  5.07700   1.000 14.15000 ? 73  ALA D C   1 
ATOM   3738 O O   . ALA D 1 72  ? -25.64100 27.41100  5.13800   1.000 13.36000 ? 73  ALA D O   1 
ATOM   3739 C CB  . ALA D 1 72  ? -23.20400 26.40900  3.17500   1.000 12.49000 ? 73  ALA D CB  1 
ATOM   3740 N N   . ASP D 1 73  ? -23.62600 27.33200  6.16300   1.000 11.04000 ? 74  ASP D N   1 
ATOM   3741 C CA  . ASP D 1 73  ? -24.26000 27.14200  7.48200   1.000 12.45000 ? 74  ASP D CA  1 
ATOM   3742 C C   . ASP D 1 73  ? -25.13600 28.34500  7.90100   1.000 12.47000 ? 74  ASP D C   1 
ATOM   3743 O O   . ASP D 1 73  ? -26.11800 28.18800  8.63300   1.000 10.41000 ? 74  ASP D O   1 
ATOM   3744 C CB  . ASP D 1 73  ? -23.17100 26.88800  8.53500   1.000 13.75000 ? 74  ASP D CB  1 
ATOM   3745 C CG  . ASP D 1 73  ? -22.68700 25.43100  8.54200   1.000 18.39000 ? 74  ASP D CG  1 
ATOM   3746 O OD1 . ASP D 1 73  ? -22.91100 24.63900  7.55100   1.000 17.64000 ? 74  ASP D OD1 1 
ATOM   3747 O OD2 . ASP D 1 73  ? -22.07200 25.07100  9.57300   1.000 17.58000 ? 74  ASP D OD2 1 
ATOM   3748 N N   . ARG D 1 74  ? -24.77400 29.57000  7.50000   1.000 12.91000 ? 75  ARG D N   1 
ATOM   3749 C CA  . ARG D 1 74  ? -25.64200 30.70000  7.82400   1.000 12.02000 ? 75  ARG D CA  1 
ATOM   3750 C C   . ARG D 1 74  ? -26.99500 30.55900  7.13100   1.000 12.71000 ? 75  ARG D C   1 
ATOM   3751 O O   . ARG D 1 74  ? -28.02400 30.87800  7.70700   1.000 12.80000 ? 75  ARG D O   1 
ATOM   3752 C CB  . ARG D 1 74  ? -24.96800 32.00700  7.39300   1.000 14.51000 ? 75  ARG D CB  1 
ATOM   3753 C CG  . ARG D 1 74  ? -23.72100 32.25200  8.27400   1.000 14.13000 ? 75  ARG D CG  1 
ATOM   3754 C CD  . ARG D 1 74  ? -22.79100 33.33200  7.71200   1.000 16.83000 ? 75  ARG D CD  1 
ATOM   3755 N NE  . ARG D 1 74  ? -21.63600 33.43800  8.63800   1.000 17.82000 ? 75  ARG D NE  1 
ATOM   3756 C CZ  . ARG D 1 74  ? -20.38300 33.50300  8.20700   1.000 21.52000 ? 75  ARG D CZ  1 
ATOM   3757 N NH1 . ARG D 1 74  ? -20.09200 33.43200  6.90000   1.000 20.72000 ? 75  ARG D NH1 1 
ATOM   3758 N NH2 . ARG D 1 74  ? -19.40500 33.66800  9.08500   1.000 16.14000 ? 75  ARG D NH2 1 
ATOM   3759 N N   . VAL D 1 75  ? -26.99300 30.07700  5.89400   1.000 9.87000  ? 76  VAL D N   1 
ATOM   3760 C CA  . VAL D 1 75  ? -28.26600 29.85200  5.21000   1.000 11.97000 ? 76  VAL D CA  1 
ATOM   3761 C C   . VAL D 1 75  ? -29.01200 28.68800  5.84100   1.000 11.49000 ? 76  VAL D C   1 
ATOM   3762 O O   . VAL D 1 75  ? -30.21600 28.75500  6.05600   1.000 12.89000 ? 76  VAL D O   1 
ATOM   3763 C CB  . VAL D 1 75  ? -27.98600 29.60600  3.73500   1.000 14.88000 ? 76  VAL D CB  1 
ATOM   3764 C CG1 . VAL D 1 75  ? -29.30300 29.15500  3.01400   1.000 17.55000 ? 76  VAL D CG1 1 
ATOM   3765 C CG2 . VAL D 1 75  ? -27.40300 30.89500  3.15500   1.000 14.53000 ? 76  VAL D CG2 1 
ATOM   3766 N N   . SER D 1 76  ? -28.31200 27.59700  6.11600   1.000 9.86000  ? 77  SER D N   1 
ATOM   3767 C CA  . SER D 1 76  ? -28.88100 26.44900  6.81700   1.000 11.21000 ? 77  SER D CA  1 
ATOM   3768 C C   . SER D 1 76  ? -29.52900 26.84400  8.13100   1.000 12.20000 ? 77  SER D C   1 
ATOM   3769 O O   . SER D 1 76  ? -30.60400 26.35100  8.46200   1.000 14.08000 ? 77  SER D O   1 
ATOM   3770 C CB  . SER D 1 76  ? -27.76300 25.42700  7.09500   1.000 9.57000  ? 77  SER D CB  1 
ATOM   3771 O OG  . SER D 1 76  ? -27.31200 24.93600  5.84900   1.000 9.43000  ? 77  SER D OG  1 
ATOM   3772 N N   . LEU D 1 77  ? -28.87700 27.70000  8.93400   1.000 10.38000 ? 78  LEU D N   1 
ATOM   3773 C CA  . LEU D 1 77  ? -29.50900 28.09300  10.18900  1.000 11.78000 ? 78  LEU D CA  1 
ATOM   3774 C C   . LEU D 1 77  ? -30.81400 28.83500  9.93500   1.000 13.65000 ? 78  LEU D C   1 
ATOM   3775 O O   . LEU D 1 77  ? -31.77000 28.74300  10.72500  1.000 12.97000 ? 78  LEU D O   1 
ATOM   3776 C CB  . LEU D 1 77  ? -28.56900 28.99100  10.99000  1.000 11.69000 ? 78  LEU D CB  1 
ATOM   3777 C CG  . LEU D 1 77  ? -27.47100 28.20400  11.70500  1.000 9.75000  ? 78  LEU D CG  1 
ATOM   3778 C CD1 . LEU D 1 77  ? -26.31600 29.20500  12.06700  1.000 13.65000 ? 78  LEU D CD1 1 
ATOM   3779 C CD2 . LEU D 1 77  ? -28.04600 27.59600  13.02900  1.000 10.87000 ? 78  LEU D CD2 1 
ATOM   3780 N N   . ARG D 1 78  ? -30.84300 29.64600  8.87700   1.000 12.04000 ? 79  ARG D N   1 
ATOM   3781 C CA  . ARG D 1 78  ? -32.12100 30.27500  8.53500   1.000 12.16000 ? 79  ARG D CA  1 
ATOM   3782 C C   . ARG D 1 78  ? -33.13800 29.23600  8.06000   1.000 16.82000 ? 79  ARG D C   1 
ATOM   3783 O O   . ARG D 1 78  ? -34.32900 29.30000  8.42700   1.000 13.38000 ? 79  ARG D O   1 
ATOM   3784 C CB  . ARG D 1 78  ? -31.88300 31.37400  7.48500   1.000 16.79000 ? 79  ARG D CB  1 
ATOM   3785 C CG  . ARG D 1 78  ? -33.19400 32.00400  7.01400   1.000 22.96000 ? 79  ARG D CG  1 
ATOM   3786 C CD  . ARG D 1 78  ? -33.90200 32.69600  8.18700   1.000 32.67000 ? 79  ARG D CD  1 
ATOM   3787 N NE  . ARG D 1 78  ? -35.26100 33.21200  7.92000   1.000 54.51000 ? 79  ARG D NE  1 
ATOM   3788 C CZ  . ARG D 1 78  ? -36.40500 32.52200  7.80300   1.000 43.73000 ? 79  ARG D CZ  1 
ATOM   3789 N NH1 . ARG D 1 78  ? -36.45000 31.18700  7.90600   1.000 23.00000 ? 79  ARG D NH1 1 
ATOM   3790 N NH2 . ARG D 1 78  ? -37.54900 33.19700  7.61400   1.000 40.94000 ? 79  ARG D NH2 1 
ATOM   3791 N N   . ASN D 1 79  ? -32.70600 28.26500  7.24300   1.000 13.08000 ? 80  ASN D N   1 
ATOM   3792 C CA  . ASN D 1 79  ? -33.64700 27.22800  6.82100   1.000 12.45000 ? 80  ASN D CA  1 
ATOM   3793 C C   . ASN D 1 79  ? -34.20000 26.48100  8.02600   1.000 17.36000 ? 80  ASN D C   1 
ATOM   3794 O O   . ASN D 1 79  ? -35.41500 26.18800  8.11800   1.000 12.50000 ? 80  ASN D O   1 
ATOM   3795 C CB  . ASN D 1 79  ? -32.95300 26.23100  5.88800   1.000 10.38000 ? 80  ASN D CB  1 
ATOM   3796 C CG  . ASN D 1 79  ? -32.57000 26.84000  4.55000   1.000 13.35000 ? 80  ASN D CG  1 
ATOM   3797 O OD1 . ASN D 1 79  ? -32.98400 27.94700  4.20400   1.000 11.38000 ? 80  ASN D OD1 1 
ATOM   3798 N ND2 . ASN D 1 79  ? -31.74000 26.12700  3.81000   1.000 11.45000 ? 80  ASN D ND2 1 
ATOM   3799 N N   . LEU D 1 80  ? -33.30200 26.12600  8.95300   1.000 10.88000 ? 81  LEU D N   1 
ATOM   3800 C CA  . LEU D 1 80  ? -33.69000 25.33800  10.13100  1.000 14.21000 ? 81  LEU D CA  1 
ATOM   3801 C C   . LEU D 1 80  ? -34.69200 26.10200  10.99100  1.000 16.09000 ? 81  LEU D C   1 
ATOM   3802 O O   . LEU D 1 80  ? -35.66000 25.52200  11.47900  1.000 12.20000 ? 81  LEU D O   1 
ATOM   3803 C CB  . LEU D 1 80  ? -32.45800 24.96900  10.98300  1.000 10.50000 ? 81  LEU D CB  1 
ATOM   3804 C CG  . LEU D 1 80  ? -31.58600 23.87000  10.27600  1.000 13.88000 ? 81  LEU D CG  1 
ATOM   3805 C CD1 . LEU D 1 80  ? -30.10300 23.93200  10.66600  1.000 11.69000 ? 81  LEU D CD1 1 
ATOM   3806 C CD2 . LEU D 1 80  ? -32.15400 22.46500  10.63900  1.000 12.71000 ? 81  LEU D CD2 1 
ATOM   3807 N N   . ARG D 1 81  ? -34.46100 27.39300  11.23600  1.000 12.89000 ? 82  ARG D N   1 
ATOM   3808 C CA  . ARG D 1 81  ? -35.49100 28.05700  12.04000  1.000 13.23000 ? 82  ARG D CA  1 
ATOM   3809 C C   . ARG D 1 81  ? -36.82900 28.12000  11.29400  1.000 16.73000 ? 82  ARG D C   1 
ATOM   3810 O O   . ARG D 1 81  ? -37.89800 27.99600  11.91600  1.000 19.13000 ? 82  ARG D O   1 
ATOM   3811 C CB  . ARG D 1 81  ? -34.97500 29.41200  12.49000  1.000 15.94000 ? 82  ARG D CB  1 
ATOM   3812 C CG  . ARG D 1 81  ? -35.12300 30.50000  11.53100  1.000 18.83000 ? 82  ARG D CG  1 
ATOM   3813 C CD  . ARG D 1 81  ? -34.63800 31.83400  12.27600  1.000 19.02000 ? 82  ARG D CD  1 
ATOM   3814 N NE  . ARG D 1 81  ? -34.78100 33.00300  11.40000  1.000 24.90000 ? 82  ARG D NE  1 
ATOM   3815 C CZ  . ARG D 1 81  ? -35.94100 33.60200  11.14300  1.000 33.72000 ? 82  ARG D CZ  1 
ATOM   3816 N NH1 . ARG D 1 81  ? -37.09800 33.15300  11.65100  1.000 22.42000 ? 82  ARG D NH1 1 
ATOM   3817 N NH2 . ARG D 1 81  ? -35.95600 34.65800  10.33200  1.000 31.07000 ? 82  ARG D NH2 1 
ATOM   3818 N N   . GLY D 1 82  ? -36.79200 28.15700  9.96200   1.000 18.47000 ? 83  GLY D N   1 
ATOM   3819 C CA  . GLY D 1 82  ? -38.03000 28.02600  9.19100   1.000 16.88000 ? 83  GLY D CA  1 
ATOM   3820 C C   . GLY D 1 82  ? -38.73600 26.70800  9.42200   1.000 16.00000 ? 83  GLY D C   1 
ATOM   3821 O O   . GLY D 1 82  ? -39.93200 26.68400  9.74400   1.000 16.81000 ? 83  GLY D O   1 
ATOM   3822 N N   . TYR D 1 83  ? -38.00800 25.59100  9.30800   1.000 12.49000 ? 84  TYR D N   1 
ATOM   3823 C CA  . TYR D 1 83  ? -38.61200 24.26600  9.56600   1.000 14.77000 ? 84  TYR D CA  1 
ATOM   3824 C C   . TYR D 1 83  ? -39.28600 24.19500  10.91500  1.000 21.54000 ? 84  TYR D C   1 
ATOM   3825 O O   . TYR D 1 83  ? -40.30200 23.53000  11.04800  1.000 14.22000 ? 84  TYR D O   1 
ATOM   3826 C CB  . TYR D 1 83  ? -37.57800 23.14200  9.55500   1.000 16.82000 ? 84  TYR D CB  1 
ATOM   3827 C CG  . TYR D 1 83  ? -36.77800 23.01400  8.27500   1.000 15.52000 ? 84  TYR D CG  1 
ATOM   3828 C CD1 . TYR D 1 83  ? -37.26400 23.50500  7.04500   1.000 13.05000 ? 84  TYR D CD1 1 
ATOM   3829 C CD2 . TYR D 1 83  ? -35.51500 22.41500  8.30000   1.000 16.31000 ? 84  TYR D CD2 1 
ATOM   3830 C CE1 . TYR D 1 83  ? -36.45900 23.41400  5.86000   1.000 11.20000 ? 84  TYR D CE1 1 
ATOM   3831 C CE2 . TYR D 1 83  ? -34.74200 22.31700  7.11000   1.000 11.15000 ? 84  TYR D CE2 1 
ATOM   3832 C CZ  . TYR D 1 83  ? -35.25500 22.79400  5.90400   1.000 14.76000 ? 84  TYR D CZ  1 
ATOM   3833 O OH  . TYR D 1 83  ? -34.50500 22.64800  4.74000   1.000 15.50000 ? 84  TYR D OH  1 
ATOM   3834 N N   . TYR D 1 84  ? -38.65800 24.75800  11.95800  1.000 11.80000 ? 85  TYR D N   1 
ATOM   3835 C CA  . TYR D 1 84  ? -39.19400 24.66400  13.33000  1.000 14.85000 ? 85  TYR D CA  1 
ATOM   3836 C C   . TYR D 1 84  ? -40.09600 25.82500  13.72000  1.000 11.72000 ? 85  TYR D C   1 
ATOM   3837 O O   . TYR D 1 84  ? -40.51900 25.90900  14.88700  1.000 14.38000 ? 85  TYR D O   1 
ATOM   3838 C CB  . TYR D 1 84  ? -38.04600 24.55900  14.32700  1.000 11.16000 ? 85  TYR D CB  1 
ATOM   3839 C CG  . TYR D 1 84  ? -37.33400 23.24200  14.21400  1.000 13.64000 ? 85  TYR D CG  1 
ATOM   3840 C CD1 . TYR D 1 84  ? -37.91100 22.07100  14.70800  1.000 12.90000 ? 85  TYR D CD1 1 
ATOM   3841 C CD2 . TYR D 1 84  ? -36.05800 23.16300  13.62100  1.000 14.12000 ? 85  TYR D CD2 1 
ATOM   3842 C CE1 . TYR D 1 84  ? -37.24400 20.85400  14.63400  1.000 12.27000 ? 85  TYR D CE1 1 
ATOM   3843 C CE2 . TYR D 1 84  ? -35.40700 21.95700  13.48900  1.000 12.48000 ? 85  TYR D CE2 1 
ATOM   3844 C CZ  . TYR D 1 84  ? -35.98400 20.81400  13.99700  1.000 16.59000 ? 85  TYR D CZ  1 
ATOM   3845 O OH  . TYR D 1 84  ? -35.29000 19.62700  13.89900  1.000 12.79000 ? 85  TYR D OH  1 
ATOM   3846 N N   . ASN D 1 85  ? -40.40800 26.72800  12.77700  1.000 12.98000 ? 86  ASN D N   1 
ATOM   3847 C CA  . ASN D 1 85  ? -41.19700 27.92700  13.06200  1.000 14.47000 ? 86  ASN D CA  1 
ATOM   3848 C C   . ASN D 1 85  ? -40.61400 28.76200  14.20100  1.000 17.25000 ? 86  ASN D C   1 
ATOM   3849 O O   . ASN D 1 85  ? -41.33700 29.28100  15.06100  1.000 15.74000 ? 86  ASN D O   1 
ATOM   3850 C CB  . ASN D 1 85  ? -42.65000 27.52500  13.33700  1.000 18.06000 ? 86  ASN D CB  1 
ATOM   3851 C CG  . ASN D 1 85  ? -43.26200 26.95700  12.12200  1.000 26.50000 ? 86  ASN D CG  1 
ATOM   3852 O OD1 . ASN D 1 85  ? -43.63400 25.79300  12.07000  1.000 26.87000 ? 86  ASN D OD1 1 
ATOM   3853 N ND2 . ASN D 1 85  ? -43.31300 27.77100  11.10000  1.000 22.47000 ? 86  ASN D ND2 1 
ATOM   3854 N N   . GLN D 1 86  ? -39.29600 28.93900  14.19700  1.000 13.93000 ? 87  GLN D N   1 
ATOM   3855 C CA  . GLN D 1 86  ? -38.66100 29.71400  15.24600  1.000 14.46000 ? 87  GLN D CA  1 
ATOM   3856 C C   . GLN D 1 86  ? -38.43800 31.15200  14.75700  1.000 15.90000 ? 87  GLN D C   1 
ATOM   3857 O O   . GLN D 1 86  ? -38.27700 31.40300  13.55200  1.000 16.13000 ? 87  GLN D O   1 
ATOM   3858 C CB  . GLN D 1 86  ? -37.33700 29.02400  15.63000  1.000 16.10000 ? 87  GLN D CB  1 
ATOM   3859 C CG  . GLN D 1 86  ? -37.61600 27.66900  16.38000  1.000 14.70000 ? 87  GLN D CG  1 
ATOM   3860 C CD  . GLN D 1 86  ? -36.36600 26.78700  16.41900  1.000 17.28000 ? 87  GLN D CD  1 
ATOM   3861 O OE1 . GLN D 1 86  ? -35.45000 26.91600  15.55700  1.000 15.12000 ? 87  GLN D OE1 1 
ATOM   3862 N NE2 . GLN D 1 86  ? -36.30700 25.90900  17.39100  1.000 13.33000 ? 87  GLN D NE2 1 
ATOM   3863 N N   . SER D 1 87  ? -38.36800 32.08600  15.70200  1.000 14.11000 ? 88  SER D N   1 
ATOM   3864 C CA  . SER D 1 87  ? -38.25800 33.49300  15.35400  1.000 16.01000 ? 88  SER D CA  1 
ATOM   3865 C C   . SER D 1 87  ? -36.80200 33.86000  15.11800  1.000 17.83000 ? 88  SER D C   1 
ATOM   3866 O O   . SER D 1 87  ? -35.88200 33.08500  15.40000  1.000 14.08000 ? 88  SER D O   1 
ATOM   3867 C CB  . SER D 1 87  ? -38.82600 34.36900  16.47800  1.000 18.80000 ? 88  SER D CB  1 
ATOM   3868 O OG  . SER D 1 87  ? -37.85200 34.43500  17.51500  1.000 22.14000 ? 88  SER D OG  1 
ATOM   3869 N N   . GLU D 1 88  ? -36.60000 35.07800  14.63700  1.000 17.12000 ? 89  GLU D N   1 
ATOM   3870 C CA  . GLU D 1 88  ? -35.24500 35.56000  14.38500  1.000 21.28000 ? 89  GLU D CA  1 
ATOM   3871 C C   . GLU D 1 88  ? -34.53100 35.98600  15.66700  1.000 20.24000 ? 89  GLU D C   1 
ATOM   3872 O O   . GLU D 1 88  ? -33.37300 36.38900  15.59500  1.000 16.01000 ? 89  GLU D O   1 
ATOM   3873 C CB  . GLU D 1 88  ? -35.30000 36.73900  13.39100  1.000 23.24000 ? 89  GLU D CB  1 
ATOM   3874 C CG  . GLU D 1 88  ? -36.09000 37.89500  13.93200  1.000 30.53000 ? 89  GLU D CG  1 
ATOM   3875 C CD  . GLU D 1 88  ? -36.02900 39.15300  13.06300  1.000 44.85000 ? 89  GLU D CD  1 
ATOM   3876 O OE1 . GLU D 1 88  ? -36.11800 39.00900  11.81000  1.000 46.94000 ? 89  GLU D OE1 1 
ATOM   3877 O OE2 . GLU D 1 88  ? -35.90200 40.26500  13.65000  1.000 43.19000 ? 89  GLU D OE2 1 
ATOM   3878 N N   . ALA D 1 89  ? -35.16900 35.89900  16.84100  1.000 13.99000 ? 90  ALA D N   1 
ATOM   3879 C CA  . ALA D 1 89  ? -34.64200 36.51500  18.04700  1.000 17.81000 ? 90  ALA D CA  1 
ATOM   3880 C C   . ALA D 1 89  ? -33.70400 35.61900  18.83100  1.000 19.99000 ? 90  ALA D C   1 
ATOM   3881 O O   . ALA D 1 89  ? -32.82500 36.13300  19.53300  1.000 16.61000 ? 90  ALA D O   1 
ATOM   3882 C CB  . ALA D 1 89  ? -35.78600 36.89800  18.99900  1.000 18.69000 ? 90  ALA D CB  1 
ATOM   3883 N N   . GLY D 1 90  ? -33.84400 34.30200  18.73100  1.000 16.48000 ? 91  GLY D N   1 
ATOM   3884 C CA  . GLY D 1 90  ? -33.04300 33.41100  19.55400  1.000 15.96000 ? 91  GLY D CA  1 
ATOM   3885 C C   . GLY D 1 90  ? -31.78400 32.87800  18.89300  1.000 13.63000 ? 91  GLY D C   1 
ATOM   3886 O O   . GLY D 1 90  ? -31.69900 32.79500  17.66300  1.000 13.63000 ? 91  GLY D O   1 
ATOM   3887 N N   . SER D 1 91  ? -30.77900 32.58300  19.72400  1.000 9.02000  ? 92  SER D N   1 
ATOM   3888 C CA  . SER D 1 91  ? -29.53700 31.93300  19.24200  1.000 12.55000 ? 92  SER D CA  1 
ATOM   3889 C C   . SER D 1 91  ? -29.77400 30.43200  19.08300  1.000 16.89000 ? 92  SER D C   1 
ATOM   3890 O O   . SER D 1 91  ? -30.38400 29.81200  19.98000  1.000 15.37000 ? 92  SER D O   1 
ATOM   3891 C CB  . SER D 1 91  ? -28.39300 32.16800  20.24300  1.000 16.72000 ? 92  SER D CB  1 
ATOM   3892 O OG  . SER D 1 91  ? -27.20900 31.38300  19.85600  1.000 15.72000 ? 92  SER D OG  1 
ATOM   3893 N N   . HIS D 1 92  ? -29.29700 29.83600  17.95700  1.000 8.88000  ? 93  HIS D N   1 
ATOM   3894 C CA  . HIS D 1 92  ? -29.39400 28.40600  17.73000  1.000 8.35000  ? 93  HIS D CA  1 
ATOM   3895 C C   . HIS D 1 92  ? -28.05000 27.84000  17.27200  1.000 10.02000 ? 93  HIS D C   1 
ATOM   3896 O O   . HIS D 1 92  ? -27.15800 28.57900  16.86100  1.000 11.86000 ? 93  HIS D O   1 
ATOM   3897 C CB  . HIS D 1 92  ? -30.48500 28.09500  16.67100  1.000 11.17000 ? 93  HIS D CB  1 
ATOM   3898 C CG  . HIS D 1 92  ? -31.85600 28.57000  17.12100  1.000 11.02000 ? 93  HIS D CG  1 
ATOM   3899 N ND1 . HIS D 1 92  ? -32.70600 27.78200  17.87700  1.000 14.85000 ? 93  HIS D ND1 1 
ATOM   3900 C CD2 . HIS D 1 92  ? -32.48100 29.77100  16.97000  1.000 11.96000 ? 93  HIS D CD2 1 
ATOM   3901 C CE1 . HIS D 1 92  ? -33.82300 28.47000  18.15000  1.000 16.50000 ? 93  HIS D CE1 1 
ATOM   3902 N NE2 . HIS D 1 92  ? -33.70700 29.68300  17.60900  1.000 15.08000 ? 93  HIS D NE2 1 
ATOM   3903 N N   . THR D 1 93  ? -27.89500 26.53300  17.40300  1.000 10.55000 ? 94  THR D N   1 
ATOM   3904 C CA  . THR D 1 93  ? -26.61100 25.86800  17.14700  1.000 9.32000  ? 94  THR D CA  1 
ATOM   3905 C C   . THR D 1 93  ? -26.75500 24.77600  16.11200  1.000 9.52000  ? 94  THR D C   1 
ATOM   3906 O O   . THR D 1 93  ? -27.66000 23.94700  16.21800  1.000 11.21000 ? 94  THR D O   1 
ATOM   3907 C CB  . THR D 1 93  ? -26.09400 25.26100  18.44100  1.000 8.93000  ? 94  THR D CB  1 
ATOM   3908 O OG1 . THR D 1 93  ? -26.00100 26.32100  19.41400  1.000 11.95000 ? 94  THR D OG1 1 
ATOM   3909 C CG2 . THR D 1 93  ? -24.66700 24.57700  18.26500  1.000 9.68000  ? 94  THR D CG2 1 
ATOM   3910 N N   . LEU D 1 94  ? -25.80700 24.70100  15.16600  1.000 7.86000  ? 95  LEU D N   1 
ATOM   3911 C CA  . LEU D 1 94  ? -25.77300 23.61400  14.19200  1.000 7.82000  ? 95  LEU D CA  1 
ATOM   3912 C C   . LEU D 1 94  ? -24.40200 22.95700  14.34500  1.000 9.88000  ? 95  LEU D C   1 
ATOM   3913 O O   . LEU D 1 94  ? -23.37600 23.64000  14.22700  1.000 9.50000  ? 95  LEU D O   1 
ATOM   3914 C CB  . LEU D 1 94  ? -25.95000 24.15000  12.74300  1.000 7.92000  ? 95  LEU D CB  1 
ATOM   3915 C CG  . LEU D 1 94  ? -25.80600 23.12600  11.64000  1.000 12.24000 ? 95  LEU D CG  1 
ATOM   3916 C CD1 . LEU D 1 94  ? -26.99600 22.11700  11.79300  1.000 12.61000 ? 95  LEU D CD1 1 
ATOM   3917 C CD2 . LEU D 1 94  ? -25.86700 23.87900  10.21500  1.000 13.08000 ? 95  LEU D CD2 1 
ATOM   3918 N N   . GLN D 1 95  ? -24.39600 21.67100  14.61200  1.000 7.63000  ? 96  GLN D N   1 
ATOM   3919 C CA  . GLN D 1 95  ? -23.16700 20.91100  14.76300  1.000 7.60000  ? 96  GLN D CA  1 
ATOM   3920 C C   . GLN D 1 95  ? -23.13000 19.79000  13.76600  1.000 7.52000  ? 96  GLN D C   1 
ATOM   3921 O O   . GLN D 1 95  ? -24.14500 19.13900  13.51500  1.000 9.90000  ? 96  GLN D O   1 
ATOM   3922 C CB  . GLN D 1 95  ? -23.00900 20.31400  16.18700  1.000 7.91000  ? 96  GLN D CB  1 
ATOM   3923 C CG  . GLN D 1 95  ? -22.76600 21.38400  17.29500  1.000 7.46000  ? 96  GLN D CG  1 
ATOM   3924 C CD  . GLN D 1 95  ? -23.13100 20.79600  18.65700  1.000 12.26000 ? 96  GLN D CD  1 
ATOM   3925 O OE1 . GLN D 1 95  ? -24.30000 20.89900  19.08200  1.000 12.98000 ? 96  GLN D OE1 1 
ATOM   3926 N NE2 . GLN D 1 95  ? -22.15400 20.15100  19.32400  1.000 7.96000  ? 96  GLN D NE2 1 
ATOM   3927 N N   . ARG D 1 96  ? -21.91400 19.50100  13.27100  1.000 7.48000  ? 97  ARG D N   1 
ATOM   3928 C CA  . ARG D 1 96  ? -21.74700 18.37100  12.39000  1.000 7.49000  ? 97  ARG D CA  1 
ATOM   3929 C C   . ARG D 1 96  ? -20.44300 17.70700  12.76500  1.000 9.32000  ? 97  ARG D C   1 
ATOM   3930 O O   . ARG D 1 96  ? -19.43700 18.39800  12.96200  1.000 10.43000 ? 97  ARG D O   1 
ATOM   3931 C CB  . ARG D 1 96  ? -21.74600 18.82100  10.89600  1.000 7.91000  ? 97  ARG D CB  1 
ATOM   3932 C CG  . ARG D 1 96  ? -21.83800 17.61700  9.88700   1.000 10.30000 ? 97  ARG D CG  1 
ATOM   3933 C CD  . ARG D 1 96  ? -22.01400 18.03500  8.40900   1.000 14.49000 ? 97  ARG D CD  1 
ATOM   3934 N NE  . ARG D 1 96  ? -22.60000 16.91500  7.66600   1.000 9.91000  ? 97  ARG D NE  1 
ATOM   3935 C CZ  . ARG D 1 96  ? -23.40500 17.05500  6.63100   1.000 14.39000 ? 97  ARG D CZ  1 
ATOM   3936 N NH1 . ARG D 1 96  ? -23.76300 18.27100  6.19900   1.000 13.01000 ? 97  ARG D NH1 1 
ATOM   3937 N NH2 . ARG D 1 96  ? -23.88800 15.95500  6.03600   1.000 15.70000 ? 97  ARG D NH2 1 
ATOM   3938 N N   . MET D 1 97  ? -20.45000 16.37200  12.82100  1.000 8.34000  ? 98  MET D N   1 
ATOM   3939 C CA  . MET D 1 97  ? -19.24600 15.59400  13.00200  1.000 8.10000  ? 98  MET D CA  1 
ATOM   3940 C C   . MET D 1 97  ? -19.16400 14.51800  11.92500  1.000 10.79000 ? 98  MET D C   1 
ATOM   3941 O O   . MET D 1 97  ? -20.12400 13.75300  11.74400  1.000 12.11000 ? 98  MET D O   1 
ATOM   3942 C CB  . MET D 1 97  ? -19.22700 14.88200  14.37500  1.000 11.87000 ? 98  MET D CB  1 
ATOM   3943 C CG  . MET D 1 97  ? -17.87000 14.27300  14.64400  1.000 20.78000 ? 98  MET D CG  1 
ATOM   3944 S SD  . MET D 1 97  ? -17.66000 12.47500  14.07200  1.000 34.88000 ? 98  MET D SD  1 
ATOM   3945 C CE  . MET D 1 97  ? -18.11900 11.52900  15.55500  1.000 38.77000 ? 98  MET D CE  1 
ATOM   3946 N N   . TYR D 1 98  ? -18.00400 14.40000  11.25700  1.000 9.72000  ? 99  TYR D N   1 
ATOM   3947 C CA  . TYR D 1 98  ? -17.82700 13.34300  10.25600  1.000 7.95000  ? 99  TYR D CA  1 
ATOM   3948 C C   . TYR D 1 98  ? -16.38000 12.84200  10.32000  1.000 12.37000 ? 99  TYR D C   1 
ATOM   3949 O O   . TYR D 1 98  ? -15.50500 13.49600  10.88300  1.000 8.39000  ? 99  TYR D O   1 
ATOM   3950 C CB  . TYR D 1 98  ? -18.18400 13.82100  8.82900   1.000 8.50000  ? 99  TYR D CB  1 
ATOM   3951 C CG  . TYR D 1 98  ? -17.30800 14.96600  8.29800   1.000 12.35000 ? 99  TYR D CG  1 
ATOM   3952 C CD1 . TYR D 1 98  ? -16.11000 14.69600  7.63300   1.000 9.90000  ? 99  TYR D CD1 1 
ATOM   3953 C CD2 . TYR D 1 98  ? -17.65600 16.30800  8.51300   1.000 10.71000 ? 99  TYR D CD2 1 
ATOM   3954 C CE1 . TYR D 1 98  ? -15.31900 15.70100  7.12600   1.000 10.62000 ? 99  TYR D CE1 1 
ATOM   3955 C CE2 . TYR D 1 98  ? -16.83500 17.35300  8.01900   1.000 10.56000 ? 99  TYR D CE2 1 
ATOM   3956 C CZ  . TYR D 1 98  ? -15.65800 17.02600  7.33700   1.000 11.77000 ? 99  TYR D CZ  1 
ATOM   3957 O OH  . TYR D 1 98  ? -14.81100 18.02300  6.78800   1.000 11.52000 ? 99  TYR D OH  1 
ATOM   3958 N N   . GLY D 1 99  ? -16.13400 11.67800  9.74000   1.000 11.45000 ? 100 GLY D N   1 
ATOM   3959 C CA  . GLY D 1 99  ? -14.77000 11.17600  9.77400   1.000 10.33000 ? 100 GLY D CA  1 
ATOM   3960 C C   . GLY D 1 99  ? -14.70700 9.73900   9.32000   1.000 14.71000 ? 100 GLY D C   1 
ATOM   3961 O O   . GLY D 1 99  ? -15.71500 9.15000   8.87400   1.000 12.69000 ? 100 GLY D O   1 
ATOM   3962 N N   . CYS D 1 100 ? -13.48300 9.18200   9.41900   1.000 10.30000 ? 101 CYS D N   1 
ATOM   3963 C CA  . CYS D 1 100 ? -13.27200 7.85800   8.91400   1.000 13.20000 ? 101 CYS D CA  1 
ATOM   3964 C C   . CYS D 1 100 ? -12.36600 7.13100   9.87500   1.000 17.33000 ? 101 CYS D C   1 
ATOM   3965 O O   . CYS D 1 100 ? -11.42400 7.72200   10.39000  1.000 14.36000 ? 101 CYS D O   1 
ATOM   3966 C CB  . CYS D 1 100 ? -12.61600 7.88000   7.52600   1.000 16.23000 ? 101 CYS D CB  1 
ATOM   3967 S SG  . CYS D 1 100 ? -11.11700 9.00000   7.32600   1.000 17.42000 ? 101 CYS D SG  1 
ATOM   3968 N N   . ASP D 1 101 ? -12.65500 5.84900   10.06600  1.000 11.90000 ? 102 ASP D N   1 
ATOM   3969 C CA  . ASP D 1 101 ? -11.79900 4.89900   10.75600  1.000 12.38000 ? 102 ASP D CA  1 
ATOM   3970 C C   . ASP D 1 101 ? -11.04000 4.07900   9.73300   1.000 12.85000 ? 102 ASP D C   1 
ATOM   3971 O O   . ASP D 1 101 ? -11.64100 3.54400   8.80100   1.000 15.13000 ? 102 ASP D O   1 
ATOM   3972 C CB  . ASP D 1 101 ? -12.65600 3.95400   11.57800  1.000 13.34000 ? 102 ASP D CB  1 
ATOM   3973 C CG  . ASP D 1 101 ? -13.43600 4.66800   12.73700  1.000 18.47000 ? 102 ASP D CG  1 
ATOM   3974 O OD1 . ASP D 1 101 ? -13.14200 5.82300   13.07200  1.000 15.20000 ? 102 ASP D OD1 1 
ATOM   3975 O OD2 . ASP D 1 101 ? -14.33900 4.02400   13.29200  1.000 17.31000 ? 102 ASP D OD2 1 
ATOM   3976 N N   . LEU D 1 102 ? -9.71700  3.93900   9.93500   1.000 12.37000 ? 103 LEU D N   1 
ATOM   3977 C CA  . LEU D 1 102 ? -8.83700  3.25400   8.98400   1.000 15.00000 ? 103 LEU D CA  1 
ATOM   3978 C C   . LEU D 1 102 ? -8.76900  1.75800   9.29600   1.000 14.24000 ? 103 LEU D C   1 
ATOM   3979 O O   . LEU D 1 102 ? -8.59800  1.37800   10.46600  1.000 15.50000 ? 103 LEU D O   1 
ATOM   3980 C CB  . LEU D 1 102 ? -7.43000  3.86200   9.11200   1.000 12.76000 ? 103 LEU D CB  1 
ATOM   3981 C CG  . LEU D 1 102 ? -6.38800  3.29100   8.14500   1.000 18.15000 ? 103 LEU D CG  1 
ATOM   3982 C CD1 . LEU D 1 102 ? -6.76400  3.74900   6.77300   1.000 14.97000 ? 103 LEU D CD1 1 
ATOM   3983 C CD2 . LEU D 1 102 ? -5.03800  3.90400   8.53700   1.000 14.82000 ? 103 LEU D CD2 1 
ATOM   3984 N N   . GLY D 1 103 ? -8.88700  0.91500   8.25600   1.000 14.94000 ? 104 GLY D N   1 
ATOM   3985 C CA  . GLY D 1 103 ? -8.83100  -0.52800  8.44000   1.000 15.60000 ? 104 GLY D CA  1 
ATOM   3986 C C   . GLY D 1 103 ? -7.41900  -1.10900  8.26800   1.000 22.01000 ? 104 GLY D C   1 
ATOM   3987 O O   . GLY D 1 103 ? -6.47300  -0.41100  7.85800   1.000 15.74000 ? 104 GLY D O   1 
ATOM   3988 N N   . PRO D 1 104 ? -7.22700  -2.37900  8.65400   1.000 19.24000 ? 105 PRO D N   1 
ATOM   3989 C CA  . PRO D 1 104 ? -5.86000  -2.95200  8.58600   1.000 20.06000 ? 105 PRO D CA  1 
ATOM   3990 C C   . PRO D 1 104 ? -5.37100  -3.11900  7.17500   1.000 16.22000 ? 105 PRO D C   1 
ATOM   3991 O O   . PRO D 1 104 ? -4.15300  -3.20100  6.97100   1.000 18.92000 ? 105 PRO D O   1 
ATOM   3992 C CB  . PRO D 1 104 ? -5.97400  -4.29700  9.33000   1.000 23.32000 ? 105 PRO D CB  1 
ATOM   3993 C CG  . PRO D 1 104 ? -7.44800  -4.63000  9.40700   1.000 23.36000 ? 105 PRO D CG  1 
ATOM   3994 C CD  . PRO D 1 104 ? -8.23900  -3.32700  9.20900   1.000 19.70000 ? 105 PRO D CD  1 
ATOM   3995 N N   . ASP D 1 105 ? -6.25100  -3.09400  6.17200   1.000 16.88000 ? 106 ASP D N   1 
ATOM   3996 C CA  . ASP D 1 105 ? -5.78200  -3.10100  4.77300   1.000 18.53000 ? 106 ASP D CA  1 
ATOM   3997 C C   . ASP D 1 105 ? -5.48400  -1.69900  4.22000   1.000 14.18000 ? 106 ASP D C   1 
ATOM   3998 O O   . ASP D 1 105 ? -5.16300  -1.55000  3.03400   1.000 16.40000 ? 106 ASP D O   1 
ATOM   3999 C CB  . ASP D 1 105 ? -6.83600  -3.79900  3.88400   1.000 13.57000 ? 106 ASP D CB  1 
ATOM   4000 C CG  . ASP D 1 105 ? -8.23500  -3.16800  3.98900   1.000 27.25000 ? 106 ASP D CG  1 
ATOM   4001 O OD1 . ASP D 1 105 ? -8.45300  -2.23400  4.83200   1.000 19.62000 ? 106 ASP D OD1 1 
ATOM   4002 O OD2 . ASP D 1 105 ? -9.13900  -3.67400  3.26700   1.000 21.12000 ? 106 ASP D OD2 1 
ATOM   4003 N N   . GLY D 1 106 ? -5.63000  -0.66200  5.03100   1.000 15.54000 ? 107 GLY D N   1 
ATOM   4004 C CA  . GLY D 1 106 ? -5.47000  0.71500   4.58400   1.000 17.54000 ? 107 GLY D CA  1 
ATOM   4005 C C   . GLY D 1 106 ? -6.67700  1.31100   3.86400   1.000 19.02000 ? 107 GLY D C   1 
ATOM   4006 O O   . GLY D 1 106 ? -6.56100  2.39800   3.27900   1.000 14.68000 ? 107 GLY D O   1 
ATOM   4007 N N   . ARG D 1 107 ? -7.78700  0.59600   3.79300   1.000 14.32000 ? 108 ARG D N   1 
ATOM   4008 C CA  . ARG D 1 107 ? -9.03800  1.15500   3.29500   1.000 14.34000 ? 108 ARG D CA  1 
ATOM   4009 C C   . ARG D 1 107 ? -9.92900  1.59700   4.45300   1.000 14.66000 ? 108 ARG D C   1 
ATOM   4010 O O   . ARG D 1 107 ? -9.64700  1.35000   5.61400   1.000 14.61000 ? 108 ARG D O   1 
ATOM   4011 C CB  . ARG D 1 107 ? -9.81600  0.12300   2.45900   1.000 14.45000 ? 108 ARG D CB  1 
ATOM   4012 C CG  . ARG D 1 107 ? -8.93800  -0.58100  1.35800   1.000 16.34000 ? 108 ARG D CG  1 
ATOM   4013 C CD  . ARG D 1 107 ? -9.84200  -1.54300  0.52800   1.000 21.58000 ? 108 ARG D CD  1 
ATOM   4014 N NE  . ARG D 1 107 ? -9.14500  -2.02900  -0.65600  1.000 23.18000 ? 108 ARG D NE  1 
ATOM   4015 C CZ  . ARG D 1 107 ? -8.60900  -3.23500  -0.74500  1.000 28.55000 ? 108 ARG D CZ  1 
ATOM   4016 N NH1 . ARG D 1 107 ? -8.55400  -4.03600  0.30900   1.000 24.22000 ? 108 ARG D NH1 1 
ATOM   4017 N NH2 . ARG D 1 107 ? -8.08900  -3.62800  -1.90800  1.000 24.60000 ? 108 ARG D NH2 1 
ATOM   4018 N N   . LEU D 1 108 ? -11.05600 2.20400   4.09200   1.000 12.69000 ? 109 LEU D N   1 
ATOM   4019 C CA  . LEU D 1 108 ? -12.05700 2.65600   5.05400   1.000 15.29000 ? 109 LEU D CA  1 
ATOM   4020 C C   . LEU D 1 108 ? -12.60300 1.47300   5.80700   1.000 14.60000 ? 109 LEU D C   1 
ATOM   4021 O O   . LEU D 1 108 ? -13.03500 0.49900   5.19700   1.000 16.19000 ? 109 LEU D O   1 
ATOM   4022 C CB  . LEU D 1 108 ? -13.19300 3.33900   4.30900   1.000 11.50000 ? 109 LEU D CB  1 
ATOM   4023 C CG  . LEU D 1 108 ? -14.26300 3.88600   5.26500   1.000 12.16000 ? 109 LEU D CG  1 
ATOM   4024 C CD1 . LEU D 1 108 ? -13.70100 5.11600   6.01100   1.000 11.92000 ? 109 LEU D CD1 1 
ATOM   4025 C CD2 . LEU D 1 108 ? -15.55500 4.22300   4.48600   1.000 13.64000 ? 109 LEU D CD2 1 
ATOM   4026 N N   . LEU D 1 109 ? -12.48800 1.50000   7.10600   1.000 12.51000 ? 110 LEU D N   1 
ATOM   4027 C CA  . LEU D 1 109 ? -13.17100 0.51500   7.93800   1.000 12.81000 ? 110 LEU D CA  1 
ATOM   4028 C C   . LEU D 1 109 ? -14.60900 0.94200   8.24200   1.000 18.28000 ? 110 LEU D C   1 
ATOM   4029 O O   . LEU D 1 109 ? -15.56800 0.14800   8.12200   1.000 12.92000 ? 110 LEU D O   1 
ATOM   4030 C CB  . LEU D 1 109 ? -12.38900 0.35000   9.25100   1.000 15.28000 ? 110 LEU D CB  1 
ATOM   4031 C CG  . LEU D 1 109 ? -12.98100 -0.65200  10.24800  1.000 20.12000 ? 110 LEU D CG  1 
ATOM   4032 C CD1 . LEU D 1 109 ? -13.02300 -2.06100  9.58700   1.000 24.31000 ? 110 LEU D CD1 1 
ATOM   4033 C CD2 . LEU D 1 109 ? -12.21800 -0.67200  11.49300  1.000 14.45000 ? 110 LEU D CD2 1 
ATOM   4034 N N   . ARG D 1 110 ? -14.78200 2.21100   8.58700   1.000 12.97000 ? 111 ARG D N   1 
ATOM   4035 C CA  . ARG D 1 110 ? -16.11100 2.72900   8.89800   1.000 15.35000 ? 111 ARG D CA  1 
ATOM   4036 C C   . ARG D 1 110 ? -16.08800 4.23100   8.66900   1.000 15.69000 ? 111 ARG D C   1 
ATOM   4037 O O   . ARG D 1 110 ? -15.17600 4.91000   9.16200   1.000 14.08000 ? 111 ARG D O   1 
ATOM   4038 C CB  . ARG D 1 110 ? -16.45800 2.42200   10.37400  1.000 21.20000 ? 111 ARG D CB  1 
ATOM   4039 C CG  . ARG D 1 110 ? -17.81100 2.93200   10.78200  1.000 24.96000 ? 111 ARG D CG  1 
ATOM   4040 C CD  . ARG D 1 110 ? -18.01800 2.74600   12.33000  1.000 25.88000 ? 111 ARG D CD  1 
ATOM   4041 N NE  . ARG D 1 110 ? -18.90000 3.76900   12.89200  1.000 42.04000 ? 111 ARG D NE  1 
ATOM   4042 C CZ  . ARG D 1 110 ? -18.46300 4.70300   13.73700  1.000 40.07000 ? 111 ARG D CZ  1 
ATOM   4043 N NH1 . ARG D 1 110 ? -17.16800 4.78300   14.08500  1.000 38.76000 ? 111 ARG D NH1 1 
ATOM   4044 N NH2 . ARG D 1 110 ? -19.32300 5.59200   14.22500  1.000 43.24000 ? 111 ARG D NH2 1 
ATOM   4045 N N   . GLY D 1 111 ? -17.09900 4.75800   7.97000   1.000 14.45000 ? 112 GLY D N   1 
ATOM   4046 C CA  . GLY D 1 111 ? -17.12400 6.19700   7.77300   1.000 15.80000 ? 112 GLY D CA  1 
ATOM   4047 C C   . GLY D 1 111 ? -18.36800 6.70800   8.45900   1.000 16.92000 ? 112 GLY D C   1 
ATOM   4048 O O   . GLY D 1 111 ? -19.32100 5.91900   8.60500   1.000 15.16000 ? 112 GLY D O   1 
ATOM   4049 N N   . TYR D 1 112 ? -18.42900 7.99100   8.84700   1.000 11.05000 ? 113 TYR D N   1 
ATOM   4050 C CA  . TYR D 1 112 ? -19.62500 8.42900   9.54800   1.000 15.08000 ? 113 TYR D CA  1 
ATOM   4051 C C   . TYR D 1 112 ? -19.83300 9.91900   9.31700   1.000 15.47000 ? 113 TYR D C   1 
ATOM   4052 O O   . TYR D 1 112 ? -18.90700 10.65900  8.96000   1.000 11.23000 ? 113 TYR D O   1 
ATOM   4053 C CB  . TYR D 1 112 ? -19.51700 8.08400   11.06300  1.000 15.28000 ? 113 TYR D CB  1 
ATOM   4054 C CG  . TYR D 1 112 ? -18.07600 8.12200   11.54200  1.000 19.56000 ? 113 TYR D CG  1 
ATOM   4055 C CD1 . TYR D 1 112 ? -17.51300 9.28700   12.00900  1.000 19.40000 ? 113 TYR D CD1 1 
ATOM   4056 C CD2 . TYR D 1 112 ? -17.26300 6.97900   11.47700  1.000 14.47000 ? 113 TYR D CD2 1 
ATOM   4057 C CE1 . TYR D 1 112 ? -16.15500 9.32600   12.48100  1.000 16.89000 ? 113 TYR D CE1 1 
ATOM   4058 C CE2 . TYR D 1 112 ? -15.92300 7.00700   11.90900  1.000 22.32000 ? 113 TYR D CE2 1 
ATOM   4059 C CZ  . TYR D 1 112 ? -15.38100 8.19700   12.40700  1.000 28.38000 ? 113 TYR D CZ  1 
ATOM   4060 O OH  . TYR D 1 112 ? -14.06300 8.24900   12.84600  1.000 23.46000 ? 113 TYR D OH  1 
ATOM   4061 N N   . ASP D 1 113 ? -21.09400 10.33800  9.46500   1.000 12.00000 ? 114 ASP D N   1 
ATOM   4062 C CA  . ASP D 1 113 ? -21.46900 11.74800  9.37300   1.000 13.18000 ? 114 ASP D CA  1 
ATOM   4063 C C   . ASP D 1 113 ? -22.76500 11.90000  10.17000  1.000 13.18000 ? 114 ASP D C   1 
ATOM   4064 O O   . ASP D 1 113 ? -23.71400 11.13300  9.93600   1.000 13.31000 ? 114 ASP D O   1 
ATOM   4065 C CB  . ASP D 1 113 ? -21.68400 12.19500  7.93700   1.000 13.63000 ? 114 ASP D CB  1 
ATOM   4066 C CG  . ASP D 1 113 ? -22.31300 13.57200  7.87500   1.000 14.28000 ? 114 ASP D CG  1 
ATOM   4067 O OD1 . ASP D 1 113 ? -21.65100 14.53500  8.33200   1.000 11.67000 ? 114 ASP D OD1 1 
ATOM   4068 O OD2 . ASP D 1 113 ? -23.44900 13.73400  7.38300   1.000 14.73000 ? 114 ASP D OD2 1 
ATOM   4069 N N   . GLN D 1 114 ? -22.77300 12.82400  11.13900  1.000 9.11000  ? 115 GLN D N   1 
ATOM   4070 C CA  . GLN D 1 114 ? -23.91900 13.07200  12.01700  1.000 12.18000 ? 115 GLN D CA  1 
ATOM   4071 C C   . GLN D 1 114 ? -24.08500 14.57500  12.22800  1.000 12.88000 ? 115 GLN D C   1 
ATOM   4072 O O   . GLN D 1 114 ? -23.09500 15.28200  12.37100  1.000 10.85000 ? 115 GLN D O   1 
ATOM   4073 C CB  . GLN D 1 114 ? -23.72500 12.42400  13.41400  1.000 17.50000 ? 115 GLN D CB  1 
ATOM   4074 C CG  . GLN D 1 114 ? -23.38700 11.00400  13.31300  1.000 31.94000 ? 115 GLN D CG  1 
ATOM   4075 C CD  . GLN D 1 114 ? -22.76400 10.44900  14.54900  1.000 32.10000 ? 115 GLN D CD  1 
ATOM   4076 O OE1 . GLN D 1 114 ? -21.70800 9.86900   14.49300  1.000 41.97000 ? 115 GLN D OE1 1 
ATOM   4077 N NE2 . GLN D 1 114 ? -23.46300 10.56200  15.65800  1.000 33.03000 ? 115 GLN D NE2 1 
ATOM   4078 N N   . SER D 1 115 ? -25.33100 15.04600  12.31500  1.000 9.26000  ? 116 SER D N   1 
ATOM   4079 C CA  . SER D 1 115 ? -25.61400 16.44000  12.57700  1.000 8.98000  ? 116 SER D CA  1 
ATOM   4080 C C   . SER D 1 115 ? -26.58000 16.56800  13.75600  1.000 11.81000 ? 116 SER D C   1 
ATOM   4081 O O   . SER D 1 115 ? -27.42100 15.68300  14.00300  1.000 10.10000 ? 116 SER D O   1 
ATOM   4082 C CB  . SER D 1 115 ? -26.24300 17.13300  11.34600  1.000 7.75000  ? 116 SER D CB  1 
ATOM   4083 O OG  . SER D 1 115 ? -25.38900 17.01400  10.21600  1.000 12.24000 ? 116 SER D OG  1 
ATOM   4084 N N   . ALA D 1 116 ? -26.43300 17.66700  14.48900  1.000 10.17000 ? 117 ALA D N   1 
ATOM   4085 C CA  . ALA D 1 116 ? -27.34500 18.04200  15.58100  1.000 9.81000  ? 117 ALA D CA  1 
ATOM   4086 C C   . ALA D 1 116 ? -27.78000 19.49300  15.43400  1.000 9.89000  ? 117 ALA D C   1 
ATOM   4087 O O   . ALA D 1 116 ? -26.97100 20.36800  15.07200  1.000 11.69000 ? 117 ALA D O   1 
ATOM   4088 C CB  . ALA D 1 116 ? -26.68000 17.86700  16.95700  1.000 9.54000  ? 117 ALA D CB  1 
ATOM   4089 N N   . TYR D 1 117 ? -29.04100 19.75500  15.75600  1.000 8.70000  ? 118 TYR D N   1 
ATOM   4090 C CA  . TYR D 1 117 ? -29.54400 21.12200  15.84700  1.000 11.71000 ? 118 TYR D CA  1 
ATOM   4091 C C   . TYR D 1 117 ? -29.96400 21.39700  17.28700  1.000 13.18000 ? 118 TYR D C   1 
ATOM   4092 O O   . TYR D 1 117 ? -30.73500 20.61500  17.85400  1.000 12.00000 ? 118 TYR D O   1 
ATOM   4093 C CB  . TYR D 1 117 ? -30.71900 21.28500  14.89700  1.000 8.02000  ? 118 TYR D CB  1 
ATOM   4094 C CG  . TYR D 1 117 ? -31.29500 22.70300  14.87900  1.000 11.16000 ? 118 TYR D CG  1 
ATOM   4095 C CD1 . TYR D 1 117 ? -30.50500 23.80400  14.46800  1.000 10.00000 ? 118 TYR D CD1 1 
ATOM   4096 C CD2 . TYR D 1 117 ? -32.63400 22.93300  15.30100  1.000 10.22000 ? 118 TYR D CD2 1 
ATOM   4097 C CE1 . TYR D 1 117 ? -31.07300 25.14100  14.45100  1.000 13.25000 ? 118 TYR D CE1 1 
ATOM   4098 C CE2 . TYR D 1 117 ? -33.23400 24.24900  15.27700  1.000 9.84000  ? 118 TYR D CE2 1 
ATOM   4099 C CZ  . TYR D 1 117 ? -32.41800 25.33200  14.86800  1.000 11.92000 ? 118 TYR D CZ  1 
ATOM   4100 O OH  . TYR D 1 117 ? -32.94300 26.59000  14.80700  1.000 9.60000  ? 118 TYR D OH  1 
ATOM   4101 N N   . ASP D 1 118 ? -29.44000 22.48200  17.87500  1.000 7.94000  ? 119 ASP D N   1 
ATOM   4102 C CA  . ASP D 1 118 ? -29.68500 22.82300  19.26100  1.000 9.21000  ? 119 ASP D CA  1 
ATOM   4103 C C   . ASP D 1 118 ? -29.37300 21.64800  20.20000  1.000 11.47000 ? 119 ASP D C   1 
ATOM   4104 O O   . ASP D 1 118 ? -30.08500 21.39900  21.17600  1.000 13.96000 ? 119 ASP D O   1 
ATOM   4105 C CB  . ASP D 1 118 ? -31.13800 23.36600  19.44400  1.000 12.71000 ? 119 ASP D CB  1 
ATOM   4106 C CG  . ASP D 1 118 ? -31.26500 24.79100  18.92800  1.000 15.75000 ? 119 ASP D CG  1 
ATOM   4107 O OD1 . ASP D 1 118 ? -30.19300 25.44900  18.84400  1.000 10.68000 ? 119 ASP D OD1 1 
ATOM   4108 O OD2 . ASP D 1 118 ? -32.38200 25.25500  18.60600  1.000 13.27000 ? 119 ASP D OD2 1 
ATOM   4109 N N   . GLY D 1 119 ? -28.31100 20.90600  19.89600  1.000 10.32000 ? 120 GLY D N   1 
ATOM   4110 C CA  . GLY D 1 119 ? -27.88200 19.81700  20.76900  1.000 12.97000 ? 120 GLY D CA  1 
ATOM   4111 C C   . GLY D 1 119 ? -28.65100 18.51600  20.62700  1.000 14.13000 ? 120 GLY D C   1 
ATOM   4112 O O   . GLY D 1 119 ? -28.36200 17.55500  21.36900  1.000 16.19000 ? 120 GLY D O   1 
ATOM   4113 N N   . LYS D 1 120 ? -29.58600 18.42400  19.68800  1.000 11.38000 ? 121 LYS D N   1 
ATOM   4114 C CA  . LYS D 1 120 ? -30.38800 17.20600  19.49800  1.000 12.99000 ? 121 LYS D CA  1 
ATOM   4115 C C   . LYS D 1 120 ? -30.07000 16.56600  18.15800  1.000 11.08000 ? 121 LYS D C   1 
ATOM   4116 O O   . LYS D 1 120 ? -29.99100 17.27500  17.16600  1.000 10.66000 ? 121 LYS D O   1 
ATOM   4117 C CB  . LYS D 1 120 ? -31.91300 17.52500  19.51700  1.000 13.40000 ? 121 LYS D CB  1 
ATOM   4118 C CG  . LYS D 1 120 ? -32.35400 17.85300  20.87100  1.000 16.76000 ? 121 LYS D CG  1 
ATOM   4119 C CD  . LYS D 1 120 ? -33.90200 17.95300  21.06300  1.000 30.27000 ? 121 LYS D CD  1 
ATOM   4120 C CE  . LYS D 1 120 ? -34.43900 19.19800  20.39200  1.000 36.04000 ? 121 LYS D CE  1 
ATOM   4121 N NZ  . LYS D 1 120 ? -35.93000 19.37600  20.63400  1.000 37.66000 ? 121 LYS D NZ  1 
ATOM   4122 N N   . ASP D 1 121 ? -29.95100 15.21300  18.12500  1.000 13.95000 ? 122 ASP D N   1 
ATOM   4123 C CA  . ASP D 1 121 ? -29.74900 14.50000  16.87200  1.000 11.62000 ? 122 ASP D CA  1 
ATOM   4124 C C   . ASP D 1 121 ? -30.71600 15.03900  15.81800  1.000 14.00000 ? 122 ASP D C   1 
ATOM   4125 O O   . ASP D 1 121 ? -31.91600 15.14300  16.06100  1.000 11.92000 ? 122 ASP D O   1 
ATOM   4126 C CB  . ASP D 1 121 ? -29.98800 12.98200  17.04300  1.000 14.16000 ? 122 ASP D CB  1 
ATOM   4127 C CG  . ASP D 1 121 ? -28.89900 12.29700  17.84300  1.000 19.03000 ? 122 ASP D CG  1 
ATOM   4128 O OD1 . ASP D 1 121 ? -27.77700 12.82500  17.89900  1.000 21.89000 ? 122 ASP D OD1 1 
ATOM   4129 O OD2 . ASP D 1 121 ? -29.12900 11.20700  18.40600  1.000 18.99000 ? 122 ASP D OD2 1 
ATOM   4130 N N   . TYR D 1 122 ? -30.19100 15.32000  14.62200  1.000 12.07000 ? 123 TYR D N   1 
ATOM   4131 C CA  . TYR D 1 122 ? -30.98700 15.83100  13.51000  1.000 13.38000 ? 123 TYR D CA  1 
ATOM   4132 C C   . TYR D 1 122 ? -30.99800 14.89500  12.29800  1.000 12.47000 ? 123 TYR D C   1 
ATOM   4133 O O   . TYR D 1 122 ? -32.06200 14.36500  11.92500  1.000 11.43000 ? 123 TYR D O   1 
ATOM   4134 C CB  . TYR D 1 122 ? -30.44700 17.21400  13.12900  1.000 13.39000 ? 123 TYR D CB  1 
ATOM   4135 C CG  . TYR D 1 122 ? -31.27100 17.91000  12.06800  1.000 11.06000 ? 123 TYR D CG  1 
ATOM   4136 C CD1 . TYR D 1 122 ? -32.48700 18.53500  12.41100  1.000 11.12000 ? 123 TYR D CD1 1 
ATOM   4137 C CD2 . TYR D 1 122 ? -30.88200 17.88700  10.70500  1.000 10.49000 ? 123 TYR D CD2 1 
ATOM   4138 C CE1 . TYR D 1 122 ? -33.26000 19.19100  11.44300  1.000 11.37000 ? 123 TYR D CE1 1 
ATOM   4139 C CE2 . TYR D 1 122 ? -31.68700 18.49800  9.72700   1.000 11.73000 ? 123 TYR D CE2 1 
ATOM   4140 C CZ  . TYR D 1 122 ? -32.85200 19.16200  10.09100  1.000 9.67000  ? 123 TYR D CZ  1 
ATOM   4141 O OH  . TYR D 1 122 ? -33.65100 19.84100  9.16100   1.000 10.75000 ? 123 TYR D OH  1 
ATOM   4142 N N   . ILE D 1 123 ? -29.83000 14.60400  11.70700  1.000 10.68000 ? 124 ILE D N   1 
ATOM   4143 C CA  . ILE D 1 123 ? -29.76000 13.65700  10.58500  1.000 11.46000 ? 124 ILE D CA  1 
ATOM   4144 C C   . ILE D 1 123 ? -28.40500 12.97600  10.61400  1.000 12.89000 ? 124 ILE D C   1 
ATOM   4145 O O   . ILE D 1 123 ? -27.41000 13.57500  11.02900  1.000 13.51000 ? 124 ILE D O   1 
ATOM   4146 C CB  . ILE D 1 123 ? -30.02300 14.37000  9.23200   1.000 13.10000 ? 124 ILE D CB  1 
ATOM   4147 C CG1 . ILE D 1 123 ? -30.21700 13.36500  8.06900   1.000 12.47000 ? 124 ILE D CG1 1 
ATOM   4148 C CG2 . ILE D 1 123 ? -28.86300 15.46400  8.92100   1.000 9.96000  ? 124 ILE D CG2 1 
ATOM   4149 C CD1 . ILE D 1 123 ? -30.77300 14.04700  6.83100   1.000 12.72000 ? 124 ILE D CD1 1 
ATOM   4150 N N   . ALA D 1 124 ? -28.37600 11.69600  10.22600  1.000 9.87000  ? 125 ALA D N   1 
ATOM   4151 C CA  . ALA D 1 124 ? -27.12600 10.93400  10.24800  1.000 12.10000 ? 125 ALA D CA  1 
ATOM   4152 C C   . ALA D 1 124 ? -27.03700 10.12500  8.97400   1.000 15.98000 ? 125 ALA D C   1 
ATOM   4153 O O   . ALA D 1 124 ? -28.06700 9.67400   8.44700   1.000 14.19000 ? 125 ALA D O   1 
ATOM   4154 C CB  . ALA D 1 124 ? -27.03600 9.99300   11.48200  1.000 13.43000 ? 125 ALA D CB  1 
ATOM   4155 N N   . LEU D 1 125 ? -25.81800 10.00500  8.44100   1.000 13.40000 ? 126 LEU D N   1 
ATOM   4156 C CA  . LEU D 1 125 ? -25.57000 9.08000   7.35400   1.000 11.20000 ? 126 LEU D CA  1 
ATOM   4157 C C   . LEU D 1 125 ? -25.58600 7.67100   7.93800   1.000 13.14000 ? 126 LEU D C   1 
ATOM   4158 O O   . LEU D 1 125 ? -25.01200 7.43000   8.99200   1.000 15.30000 ? 126 LEU D O   1 
ATOM   4159 C CB  . LEU D 1 125 ? -24.21300 9.41900   6.69700   1.000 11.91000 ? 126 LEU D CB  1 
ATOM   4160 C CG  . LEU D 1 125 ? -23.74300 8.65100   5.45900   1.000 9.57000  ? 126 LEU D CG  1 
ATOM   4161 C CD1 . LEU D 1 125 ? -24.66600 8.78100   4.30300   1.000 12.22000 ? 126 LEU D CD1 1 
ATOM   4162 C CD2 . LEU D 1 125 ? -22.28500 9.12500   5.09900   1.000 10.64000 ? 126 LEU D CD2 1 
ATOM   4163 N N   . ASN D 1 126 ? -26.29200 6.74200   7.27400   1.000 16.86000 ? 127 ASN D N   1 
ATOM   4164 C CA  . ASN D 1 126 ? -26.35600 5.35900   7.73700   1.000 14.57000 ? 127 ASN D CA  1 
ATOM   4165 C C   . ASN D 1 126 ? -25.01000 4.65300   7.49700   1.000 19.56000 ? 127 ASN D C   1 
ATOM   4166 O O   . ASN D 1 126 ? -24.17700 5.09600   6.70600   1.000 16.87000 ? 127 ASN D O   1 
ATOM   4167 C CB  . ASN D 1 126 ? -27.48200 4.59900   7.04000   1.000 16.53000 ? 127 ASN D CB  1 
ATOM   4168 C CG  . ASN D 1 126 ? -28.85900 5.10300   7.47400   1.000 22.91000 ? 127 ASN D CG  1 
ATOM   4169 O OD1 . ASN D 1 126 ? -28.98500 5.62700   8.57300   1.000 19.27000 ? 127 ASN D OD1 1 
ATOM   4170 N ND2 . ASN D 1 126 ? -29.88200 4.96500   6.62600   1.000 18.27000 ? 127 ASN D ND2 1 
ATOM   4171 N N   . GLU D 1 127 ? -24.77500 3.56500   8.20700   1.000 19.36000 ? 128 GLU D N   1 
ATOM   4172 C CA  . GLU D 1 127 ? -23.51400 2.83700   8.09200   1.000 24.30000 ? 128 GLU D CA  1 
ATOM   4173 C C   . GLU D 1 127 ? -23.14000 2.44600   6.67200   1.000 22.42000 ? 128 GLU D C   1 
ATOM   4174 O O   . GLU D 1 127 ? -21.99600 2.41700   6.33300   1.000 25.15000 ? 128 GLU D O   1 
ATOM   4175 C CB  . GLU D 1 127 ? -23.54700 1.55100   8.89700   1.000 29.56000 ? 128 GLU D CB  1 
ATOM   4176 C CG  . GLU D 1 127 ? -23.00500 1.63500   10.29000  1.000 44.71000 ? 128 GLU D CG  1 
ATOM   4177 C CD  . GLU D 1 127 ? -21.54700 1.19800   10.48100  1.000 55.96000 ? 128 GLU D CD  1 
ATOM   4178 O OE1 . GLU D 1 127 ? -21.04700 0.23800   9.87100   1.000 54.71000 ? 128 GLU D OE1 1 
ATOM   4179 O OE2 . GLU D 1 127 ? -20.89400 1.81500   11.29500  1.000 47.67000 ? 128 GLU D OE2 1 
ATOM   4180 N N   . ASP D 1 128 ? -24.12100 2.13300   5.86000   1.000 22.81000 ? 129 ASP D N   1 
ATOM   4181 C CA  . ASP D 1 128 ? -23.80600 1.72400   4.49200   1.000 23.64000 ? 129 ASP D CA  1 
ATOM   4182 C C   . ASP D 1 128 ? -23.43200 2.88000   3.58000   1.000 19.33000 ? 129 ASP D C   1 
ATOM   4183 O O   . ASP D 1 128 ? -23.10700 2.64500   2.43500   1.000 17.11000 ? 129 ASP D O   1 
ATOM   4184 C CB  . ASP D 1 128 ? -24.98500 0.93000   3.89300   1.000 29.01000 ? 129 ASP D CB  1 
ATOM   4185 C CG  . ASP D 1 128 ? -26.25100 1.77900   3.65700   1.000 25.23000 ? 129 ASP D CG  1 
ATOM   4186 O OD1 . ASP D 1 128 ? -26.26100 3.04000   3.76100   1.000 19.94000 ? 129 ASP D OD1 1 
ATOM   4187 O OD2 . ASP D 1 128 ? -27.28300 1.16900   3.29600   1.000 29.98000 ? 129 ASP D OD2 1 
ATOM   4188 N N   . LEU D 1 129 ? -23.43800 4.12600   4.04900   1.000 15.29000 ? 130 LEU D N   1 
ATOM   4189 C CA  . LEU D 1 129 ? -23.01500 5.28800   3.27100   1.000 12.42000 ? 130 LEU D CA  1 
ATOM   4190 C C   . LEU D 1 129 ? -23.90800 5.54400   2.05500   1.000 18.87000 ? 130 LEU D C   1 
ATOM   4191 O O   . LEU D 1 129 ? -23.51200 6.26800   1.13200   1.000 17.16000 ? 130 LEU D O   1 
ATOM   4192 C CB  . LEU D 1 129 ? -21.53600 5.20900   2.82100   1.000 16.55000 ? 130 LEU D CB  1 
ATOM   4193 C CG  . LEU D 1 129 ? -20.61000 4.73800   3.94300   1.000 17.07000 ? 130 LEU D CG  1 
ATOM   4194 C CD1 . LEU D 1 129 ? -19.14300 4.74300   3.47400   1.000 18.69000 ? 130 LEU D CD1 1 
ATOM   4195 C CD2 . LEU D 1 129 ? -20.78800 5.62400   5.15300   1.000 12.87000 ? 130 LEU D CD2 1 
ATOM   4196 N N   . ARG D 1 130 ? -25.13800 5.02200   2.07200   1.000 16.46000 ? 131 ARG D N   1 
ATOM   4197 C CA  . ARG D 1 130 ? -26.03100 5.14600   0.92200   1.000 21.91000 ? 131 ARG D CA  1 
ATOM   4198 C C   . ARG D 1 130 ? -27.29300 5.93600   1.23500   1.000 22.28000 ? 131 ARG D C   1 
ATOM   4199 O O   . ARG D 1 130 ? -27.95700 6.36400   0.29700   1.000 21.56000 ? 131 ARG D O   1 
ATOM   4200 C CB  . ARG D 1 130 ? -26.49000 3.74500   0.41100   1.000 19.53000 ? 131 ARG D CB  1 
ATOM   4201 C CG  . ARG D 1 130 ? -25.39200 2.77200   0.07600   1.000 24.26000 ? 131 ARG D CG  1 
ATOM   4202 C CD  . ARG D 1 130 ? -25.88000 1.64900   -0.85400  1.000 23.36000 ? 131 ARG D CD  1 
ATOM   4203 N NE  . ARG D 1 130 ? -26.06500 2.19200   -2.19400  1.000 38.52000 ? 131 ARG D NE  1 
ATOM   4204 C CZ  . ARG D 1 130 ? -25.12300 2.21700   -3.12800  1.000 36.65000 ? 131 ARG D CZ  1 
ATOM   4205 N NH1 . ARG D 1 130 ? -23.95800 1.60300   -2.95300  1.000 46.07000 ? 131 ARG D NH1 1 
ATOM   4206 N NH2 . ARG D 1 130 ? -25.33600 2.90700   -4.24200  1.000 24.98000 ? 131 ARG D NH2 1 
ATOM   4207 N N   . SER D 1 131 ? -27.63100 6.13900   2.50500   1.000 14.80000 ? 132 SER D N   1 
ATOM   4208 C CA  . SER D 1 131 ? -28.93400 6.65800   2.89400   1.000 20.42000 ? 132 SER D CA  1 
ATOM   4209 C C   . SER D 1 131 ? -28.79800 7.39300   4.23100   1.000 17.24000 ? 132 SER D C   1 
ATOM   4210 O O   . SER D 1 131 ? -27.75400 7.35100   4.88200   1.000 16.83000 ? 132 SER D O   1 
ATOM   4211 C CB  . SER D 1 131 ? -29.93000 5.50600   3.00500   1.000 21.09000 ? 132 SER D CB  1 
ATOM   4212 O OG  . SER D 1 131 ? -29.34900 4.46300   3.81200   1.000 29.44000 ? 132 SER D OG  1 
ATOM   4213 N N   . TRP D 1 132 ? -29.89300 7.99500   4.68400   1.000 20.61000 ? 133 TRP D N   1 
ATOM   4214 C CA  . TRP D 1 132 ? -29.86700 8.86100   5.85600   1.000 18.95000 ? 133 TRP D CA  1 
ATOM   4215 C C   . TRP D 1 132 ? -30.90000 8.39900   6.83800   1.000 22.41000 ? 133 TRP D C   1 
ATOM   4216 O O   . TRP D 1 132 ? -31.87400 7.75400   6.43600   1.000 16.83000 ? 133 TRP D O   1 
ATOM   4217 C CB  . TRP D 1 132 ? -30.21000 10.28100  5.48800   1.000 17.04000 ? 133 TRP D CB  1 
ATOM   4218 C CG  . TRP D 1 132 ? -29.39700 10.77000  4.36100   1.000 19.57000 ? 133 TRP D CG  1 
ATOM   4219 C CD1 . TRP D 1 132 ? -29.65900 10.68000  2.99000   1.000 16.07000 ? 133 TRP D CD1 1 
ATOM   4220 C CD2 . TRP D 1 132 ? -28.15300 11.40000  4.50500   1.000 19.78000 ? 133 TRP D CD2 1 
ATOM   4221 N NE1 . TRP D 1 132 ? -28.61900 11.26500  2.30000   1.000 21.59000 ? 133 TRP D NE1 1 
ATOM   4222 C CE2 . TRP D 1 132 ? -27.68300 11.70000  3.22000   1.000 13.14000 ? 133 TRP D CE2 1 
ATOM   4223 C CE3 . TRP D 1 132 ? -27.39100 11.76000  5.62400   1.000 13.07000 ? 133 TRP D CE3 1 
ATOM   4224 C CZ2 . TRP D 1 132 ? -26.46500 12.32800  3.00400   1.000 22.11000 ? 133 TRP D CZ2 1 
ATOM   4225 C CZ3 . TRP D 1 132 ? -26.24800 12.39600  5.43300   1.000 19.43000 ? 133 TRP D CZ3 1 
ATOM   4226 C CH2 . TRP D 1 132 ? -25.75900 12.69500  4.12200   1.000 20.70000 ? 133 TRP D CH2 1 
ATOM   4227 N N   . THR D 1 133 ? -30.66900 8.71600   8.12100   1.000 15.28000 ? 134 THR D N   1 
ATOM   4228 C CA  . THR D 1 133 ? -31.69600 8.56600   9.16000   1.000 16.46000 ? 134 THR D CA  1 
ATOM   4229 C C   . THR D 1 133 ? -32.01200 9.96200   9.66500   1.000 16.56000 ? 134 THR D C   1 
ATOM   4230 O O   . THR D 1 133 ? -31.12100 10.65500  10.17800  1.000 15.43000 ? 134 THR D O   1 
ATOM   4231 C CB  . THR D 1 133 ? -31.23300 7.64300   10.28500  1.000 20.19000 ? 134 THR D CB  1 
ATOM   4232 O OG1 . THR D 1 133 ? -31.05700 6.32800   9.72500   1.000 21.65000 ? 134 THR D OG1 1 
ATOM   4233 C CG2 . THR D 1 133 ? -32.22500 7.61500   11.44700  1.000 17.47000 ? 134 THR D CG2 1 
ATOM   4234 N N   . ALA D 1 134 ? -33.27600 10.35300  9.54600   1.000 13.29000 ? 135 ALA D N   1 
ATOM   4235 C CA  . ALA D 1 134 ? -33.75900 11.68200  9.92500   1.000 12.85000 ? 135 ALA D CA  1 
ATOM   4236 C C   . ALA D 1 134 ? -34.49700 11.56700  11.25200  1.000 16.40000 ? 135 ALA D C   1 
ATOM   4237 O O   . ALA D 1 134 ? -35.36400 10.68800  11.41500  1.000 14.27000 ? 135 ALA D O   1 
ATOM   4238 C CB  . ALA D 1 134 ? -34.69300 12.24500  8.85400   1.000 12.26000 ? 135 ALA D CB  1 
ATOM   4239 N N   . ALA D 1 135 ? -34.20500 12.48600  12.17500  1.000 11.85000 ? 136 ALA D N   1 
ATOM   4240 C CA  . ALA D 1 135 ? -34.76200 12.31800  13.52100  1.000 15.04000 ? 136 ALA D CA  1 
ATOM   4241 C C   . ALA D 1 135 ? -36.19800 12.84500  13.67000  1.000 16.58000 ? 136 ALA D C   1 
ATOM   4242 O O   . ALA D 1 135 ? -36.92700 12.38200  14.55800  1.000 15.99000 ? 136 ALA D O   1 
ATOM   4243 C CB  . ALA D 1 135 ? -33.81800 12.96700  14.54600  1.000 15.69000 ? 136 ALA D CB  1 
ATOM   4244 N N   . ASP D 1 136 ? -36.62300 13.81000  12.85500  1.000 16.07000 ? 137 ASP D N   1 
ATOM   4245 C CA  . ASP D 1 136 ? -37.92200 14.44700  13.00200  1.000 11.65000 ? 137 ASP D CA  1 
ATOM   4246 C C   . ASP D 1 136 ? -38.37300 14.92200  11.63000  1.000 14.54000 ? 137 ASP D C   1 
ATOM   4247 O O   . ASP D 1 136 ? -37.65200 14.78100  10.64300  1.000 14.24000 ? 137 ASP D O   1 
ATOM   4248 C CB  . ASP D 1 136 ? -37.90100 15.58500  14.02700  1.000 12.63000 ? 137 ASP D CB  1 
ATOM   4249 C CG  . ASP D 1 136 ? -36.88800 16.70300  13.68100  1.000 18.90000 ? 137 ASP D CG  1 
ATOM   4250 O OD1 . ASP D 1 136 ? -36.49200 16.85100  12.48200  1.000 13.72000 ? 137 ASP D OD1 1 
ATOM   4251 O OD2 . ASP D 1 136 ? -36.46700 17.44900  14.61400  1.000 17.01000 ? 137 ASP D OD2 1 
ATOM   4252 N N   . THR D 1 137 ? -39.56700 15.54700  11.56600  1.000 14.44000 ? 138 THR D N   1 
ATOM   4253 C CA  . THR D 1 137 ? -40.07900 15.90200  10.25200  1.000 13.27000 ? 138 THR D CA  1 
ATOM   4254 C C   . THR D 1 137 ? -39.28000 17.02500  9.60700   1.000 14.99000 ? 138 THR D C   1 
ATOM   4255 O O   . THR D 1 137 ? -39.25300 17.12900  8.37500   1.000 14.44000 ? 138 THR D O   1 
ATOM   4256 C CB  . THR D 1 137 ? -41.56700 16.31300  10.34700  1.000 18.33000 ? 138 THR D CB  1 
ATOM   4257 O OG1 . THR D 1 137 ? -41.67900 17.39100  11.24800  1.000 18.50000 ? 138 THR D OG1 1 
ATOM   4258 C CG2 . THR D 1 137 ? -42.39200 15.18000  10.95100  1.000 15.45000 ? 138 THR D CG2 1 
ATOM   4259 N N   . ALA D 1 138 ? -38.63400 17.88300  10.39700  1.000 13.62000 ? 139 ALA D N   1 
ATOM   4260 C CA  . ALA D 1 138 ? -37.74400 18.89000  9.79100   1.000 14.07000 ? 139 ALA D CA  1 
ATOM   4261 C C   . ALA D 1 138 ? -36.57700 18.22200  9.06300   1.000 14.84000 ? 139 ALA D C   1 
ATOM   4262 O O   . ALA D 1 138 ? -36.28400 18.49900  7.87700   1.000 9.93000  ? 139 ALA D O   1 
ATOM   4263 C CB  . ALA D 1 138 ? -37.17100 19.81900  10.87700  1.000 13.79000 ? 139 ALA D CB  1 
ATOM   4264 N N   . ALA D 1 139 ? -35.90200 17.32100  9.76600   1.000 12.37000 ? 140 ALA D N   1 
ATOM   4265 C CA  . ALA D 1 139 ? -34.79500 16.60000  9.14800   1.000 13.11000 ? 140 ALA D CA  1 
ATOM   4266 C C   . ALA D 1 139 ? -35.23100 15.79500  7.93300   1.000 13.97000 ? 140 ALA D C   1 
ATOM   4267 O O   . ALA D 1 139 ? -34.39900 15.50100  7.07700   1.000 11.50000 ? 140 ALA D O   1 
ATOM   4268 C CB  . ALA D 1 139 ? -34.14300 15.66700  10.18100  1.000 11.55000 ? 140 ALA D CB  1 
ATOM   4269 N N   . GLN D 1 140 ? -36.51000 15.41900  7.82100   1.000 11.53000 ? 141 GLN D N   1 
ATOM   4270 C CA  . GLN D 1 140 ? -36.90500 14.68600  6.61700   1.000 12.12000 ? 141 GLN D CA  1 
ATOM   4271 C C   . GLN D 1 140 ? -36.93100 15.59800  5.38300   1.000 14.77000 ? 141 GLN D C   1 
ATOM   4272 O O   . GLN D 1 140 ? -36.75800 15.12600  4.24200   1.000 14.75000 ? 141 GLN D O   1 
ATOM   4273 C CB  . GLN D 1 140 ? -38.27700 14.01000  6.83700   1.000 12.67000 ? 141 GLN D CB  1 
ATOM   4274 C CG  . GLN D 1 140 ? -38.23500 12.92800  7.90900   1.000 14.54000 ? 141 GLN D CG  1 
ATOM   4275 C CD  . GLN D 1 140 ? -39.58700 12.23500  8.04100   1.000 27.39000 ? 141 GLN D CD  1 
ATOM   4276 O OE1 . GLN D 1 140 ? -40.47100 12.78800  8.65600   1.000 21.45000 ? 141 GLN D OE1 1 
ATOM   4277 N NE2 . GLN D 1 140 ? -39.69100 10.97600  7.59800   1.000 25.36000 ? 141 GLN D NE2 1 
ATOM   4278 N N   . ILE D 1 141 ? -37.14600 16.88500  5.59700   1.000 12.02000 ? 142 ILE D N   1 
ATOM   4279 C CA  . ILE D 1 141 ? -36.99900 17.86300  4.53400   1.000 13.48000 ? 142 ILE D CA  1 
ATOM   4280 C C   . ILE D 1 141 ? -35.54900 17.92200  4.09400   1.000 15.67000 ? 142 ILE D C   1 
ATOM   4281 O O   . ILE D 1 141 ? -35.24500 17.86600  2.89700   1.000 11.78000 ? 142 ILE D O   1 
ATOM   4282 C CB  . ILE D 1 141 ? -37.48200 19.26100  4.97900   1.000 13.11000 ? 142 ILE D CB  1 
ATOM   4283 C CG1 . ILE D 1 141 ? -38.99300 19.26300  5.33700   1.000 15.43000 ? 142 ILE D CG1 1 
ATOM   4284 C CG2 . ILE D 1 141 ? -37.25200 20.27200  3.79100   1.000 13.57000 ? 142 ILE D CG2 1 
ATOM   4285 C CD1 . ILE D 1 141 ? -39.85300 18.85200  4.08700   1.000 16.92000 ? 142 ILE D CD1 1 
ATOM   4286 N N   . THR D 1 142 ? -34.62800 18.04700  5.05800   1.000 14.38000 ? 143 THR D N   1 
ATOM   4287 C CA  . THR D 1 142 ? -33.20400 18.06100  4.68800   1.000 12.17000 ? 143 THR D CA  1 
ATOM   4288 C C   . THR D 1 142 ? -32.84600 16.79000  3.92500   1.000 14.70000 ? 143 THR D C   1 
ATOM   4289 O O   . THR D 1 142 ? -32.13800 16.83200  2.90600   1.000 13.54000 ? 143 THR D O   1 
ATOM   4290 C CB  . THR D 1 142 ? -32.33900 18.19000  5.96200   1.000 12.08000 ? 143 THR D CB  1 
ATOM   4291 O OG1 . THR D 1 142 ? -32.66800 19.41300  6.64400   1.000 12.26000 ? 143 THR D OG1 1 
ATOM   4292 C CG2 . THR D 1 142 ? -30.82900 18.17800  5.61400   1.000 9.46000  ? 143 THR D CG2 1 
ATOM   4293 N N   . GLN D 1 143 ? -33.31100 15.63500  4.42400   1.000 13.15000 ? 144 GLN D N   1 
ATOM   4294 C CA  . GLN D 1 143 ? -33.02600 14.37400  3.73100   1.000 13.63000 ? 144 GLN D CA  1 
ATOM   4295 C C   . GLN D 1 143 ? -33.47800 14.40900  2.26500   1.000 14.47000 ? 144 GLN D C   1 
ATOM   4296 O O   . GLN D 1 143 ? -32.75800 13.95400  1.36200   1.000 12.21000 ? 144 GLN D O   1 
ATOM   4297 C CB  . GLN D 1 143 ? -33.71600 13.24600  4.47300   1.000 12.07000 ? 144 GLN D CB  1 
ATOM   4298 C CG  . GLN D 1 143 ? -33.56200 11.88400  3.79100   1.000 16.72000 ? 144 GLN D CG  1 
ATOM   4299 C CD  . GLN D 1 143 ? -34.06500 10.74100  4.63800   1.000 23.25000 ? 144 GLN D CD  1 
ATOM   4300 O OE1 . GLN D 1 143 ? -34.32700 10.88900  5.81900   1.000 26.67000 ? 144 GLN D OE1 1 
ATOM   4301 N NE2 . GLN D 1 143 ? -34.19200 9.59100   4.03900   1.000 23.21000 ? 144 GLN D NE2 1 
ATOM   4302 N N   . ARG D 1 144 ? -34.64800 14.98900  2.01200   1.000 13.84000 ? 145 ARG D N   1 
ATOM   4303 C CA  . ARG D 1 144 ? -35.16100 15.03800  0.65000   1.000 15.02000 ? 145 ARG D CA  1 
ATOM   4304 C C   . ARG D 1 144 ? -34.28900 15.91100  -0.22600  1.000 12.92000 ? 145 ARG D C   1 
ATOM   4305 O O   . ARG D 1 144 ? -33.96600 15.54000  -1.34700  1.000 13.65000 ? 145 ARG D O   1 
ATOM   4306 C CB  . ARG D 1 144 ? -36.61600 15.52800  0.66100   1.000 13.20000 ? 145 ARG D CB  1 
ATOM   4307 C CG  . ARG D 1 144 ? -37.50100 14.39000  1.08100   1.000 12.21000 ? 145 ARG D CG  1 
ATOM   4308 C CD  . ARG D 1 144 ? -38.93300 14.87200  1.39300   1.000 18.22000 ? 145 ARG D CD  1 
ATOM   4309 N NE  . ARG D 1 144 ? -39.52600 15.52700  0.23200   1.000 14.33000 ? 145 ARG D NE  1 
ATOM   4310 C CZ  . ARG D 1 144 ? -40.56200 16.36200  0.36100   1.000 24.08000 ? 145 ARG D CZ  1 
ATOM   4311 N NH1 . ARG D 1 144 ? -41.09200 16.61300  1.53600   1.000 15.39000 ? 145 ARG D NH1 1 
ATOM   4312 N NH2 . ARG D 1 144 ? -41.08500 16.95400  -0.71400  1.000 20.13000 ? 145 ARG D NH2 1 
ATOM   4313 N N   . LYS D 1 145 ? -33.78600 17.00600  0.32400   1.000 13.60000 ? 146 LYS D N   1 
ATOM   4314 C CA  . LYS D 1 145 ? -32.87700 17.84800  -0.43900  1.000 14.35000 ? 146 LYS D CA  1 
ATOM   4315 C C   . LYS D 1 145 ? -31.57900 17.10000  -0.73500  1.000 13.28000 ? 146 LYS D C   1 
ATOM   4316 O O   . LYS D 1 145 ? -31.04300 17.17400  -1.85100  1.000 13.42000 ? 146 LYS D O   1 
ATOM   4317 C CB  . LYS D 1 145 ? -32.55900 19.10500  0.39000   1.000 13.99000 ? 146 LYS D CB  1 
ATOM   4318 C CG  . LYS D 1 145 ? -33.67900 20.12000  0.56000   1.000 12.92000 ? 146 LYS D CG  1 
ATOM   4319 C CD  . LYS D 1 145 ? -32.99900 21.46800  1.05000   1.000 17.04000 ? 146 LYS D CD  1 
ATOM   4320 C CE  . LYS D 1 145 ? -33.94000 22.41300  1.75100   1.000 25.26000 ? 146 LYS D CE  1 
ATOM   4321 N NZ  . LYS D 1 145 ? -33.35700 23.72000  2.29500   1.000 18.07000 ? 146 LYS D NZ  1 
ATOM   4322 N N   . TRP D 1 146 ? -31.04300 16.41000  0.26400   1.000 11.90000 ? 147 TRP D N   1 
ATOM   4323 C CA  . TRP D 1 146 ? -29.76800 15.74500  0.07600   1.000 12.67000 ? 147 TRP D CA  1 
ATOM   4324 C C   . TRP D 1 146 ? -29.93400 14.54500  -0.83700  1.000 17.50000 ? 147 TRP D C   1 
ATOM   4325 O O   . TRP D 1 146 ? -29.02900 14.20700  -1.61300  1.000 15.49000 ? 147 TRP D O   1 
ATOM   4326 C CB  . TRP D 1 146 ? -29.17200 15.32000  1.42800   1.000 11.36000 ? 147 TRP D CB  1 
ATOM   4327 C CG  . TRP D 1 146 ? -28.75300 16.56000  2.25600   1.000 12.10000 ? 147 TRP D CG  1 
ATOM   4328 C CD1 . TRP D 1 146 ? -28.87800 17.88400  1.88000   1.000 11.10000 ? 147 TRP D CD1 1 
ATOM   4329 C CD2 . TRP D 1 146 ? -28.18400 16.55800  3.55900   1.000 12.48000 ? 147 TRP D CD2 1 
ATOM   4330 N NE1 . TRP D 1 146 ? -28.38900 18.71600  2.89500   1.000 11.97000 ? 147 TRP D NE1 1 
ATOM   4331 C CE2 . TRP D 1 146 ? -27.97800 17.92200  3.93800   1.000 11.03000 ? 147 TRP D CE2 1 
ATOM   4332 C CE3 . TRP D 1 146 ? -27.81900 15.53500  4.46100   1.000 12.00000 ? 147 TRP D CE3 1 
ATOM   4333 C CZ2 . TRP D 1 146 ? -27.43700 18.27400  5.16800   1.000 10.00000 ? 147 TRP D CZ2 1 
ATOM   4334 C CZ3 . TRP D 1 146 ? -27.25700 15.90300  5.69100   1.000 12.02000 ? 147 TRP D CZ3 1 
ATOM   4335 C CH2 . TRP D 1 146 ? -27.07400 17.24000  6.03100   1.000 10.90000 ? 147 TRP D CH2 1 
ATOM   4336 N N   . GLU D 1 147 ? -31.06200 13.87600  -0.75100  1.000 13.78000 ? 148 GLU D N   1 
ATOM   4337 C CA  . GLU D 1 147 ? -31.30500 12.78700  -1.69800  1.000 13.67000 ? 148 GLU D CA  1 
ATOM   4338 C C   . GLU D 1 147 ? -31.38600 13.31100  -3.13000  1.000 18.06000 ? 148 GLU D C   1 
ATOM   4339 O O   . GLU D 1 147 ? -30.76900 12.75200  -4.05600  1.000 15.85000 ? 148 GLU D O   1 
ATOM   4340 C CB  . GLU D 1 147 ? -32.60600 12.05500  -1.33000  1.000 18.86000 ? 148 GLU D CB  1 
ATOM   4341 C CG  . GLU D 1 147 ? -32.47300 11.07800  -0.17800  1.000 18.36000 ? 148 GLU D CG  1 
ATOM   4342 C CD  . GLU D 1 147 ? -33.79200 10.62900  0.40000   1.000 28.15000 ? 148 GLU D CD  1 
ATOM   4343 O OE1 . GLU D 1 147 ? -34.86300 11.25800  0.11200   1.000 24.08000 ? 148 GLU D OE1 1 
ATOM   4344 O OE2 . GLU D 1 147 ? -33.75100 9.66100   1.22000   1.000 25.43000 ? 148 GLU D OE2 1 
ATOM   4345 N N   . ALA D 1 148 ? -32.16300 14.36800  -3.34200  1.000 17.31000 ? 149 ALA D N   1 
ATOM   4346 C CA  . ALA D 1 148 ? -32.24200 14.96500  -4.67900  1.000 15.71000 ? 149 ALA D CA  1 
ATOM   4347 C C   . ALA D 1 148 ? -30.86300 15.35200  -5.20200  1.000 21.76000 ? 149 ALA D C   1 
ATOM   4348 O O   . ALA D 1 148 ? -30.58400 15.20800  -6.39300  1.000 21.60000 ? 149 ALA D O   1 
ATOM   4349 C CB  . ALA D 1 148 ? -33.20000 16.15400  -4.65700  1.000 19.71000 ? 149 ALA D CB  1 
ATOM   4350 N N   . ALA D 1 149 ? -29.98300 15.82900  -4.34200  1.000 18.82000 ? 150 ALA D N   1 
ATOM   4351 C CA  . ALA D 1 149 ? -28.62300 16.19300  -4.74600  1.000 19.22000 ? 150 ALA D CA  1 
ATOM   4352 C C   . ALA D 1 149 ? -27.69100 15.00800  -4.84900  1.000 17.15000 ? 150 ALA D C   1 
ATOM   4353 O O   . ALA D 1 149 ? -26.52700 15.19800  -5.20100  1.000 16.09000 ? 150 ALA D O   1 
ATOM   4354 C CB  . ALA D 1 149 ? -28.02400 17.15100  -3.74000  1.000 17.81000 ? 150 ALA D CB  1 
ATOM   4355 N N   . ARG D 1 150 ? -28.15400 13.79200  -4.54400  1.000 14.58000 ? 151 ARG D N   1 
ATOM   4356 C CA  . ARG D 1 150 ? -27.30000 12.61100  -4.60000  1.000 16.81000 ? 151 ARG D CA  1 
ATOM   4357 C C   . ARG D 1 150 ? -26.05000 12.80600  -3.73100  1.000 20.73000 ? 151 ARG D C   1 
ATOM   4358 O O   . ARG D 1 150 ? -24.94000 12.34900  -4.06800  1.000 18.70000 ? 151 ARG D O   1 
ATOM   4359 C CB  . ARG D 1 150 ? -26.91700 12.29100  -6.03500  1.000 15.34000 ? 151 ARG D CB  1 
ATOM   4360 C CG  . ARG D 1 150 ? -28.14300 11.65800  -6.75500  1.000 17.52000 ? 151 ARG D CG  1 
ATOM   4361 C CD  . ARG D 1 150 ? -27.99100 11.73800  -8.27200  1.000 39.47000 ? 151 ARG D CD  1 
ATOM   4362 N NE  . ARG D 1 150 ? -26.86600 10.94700  -8.75400  1.000 40.06000 ? 151 ARG D NE  1 
ATOM   4363 C CZ  . ARG D 1 150 ? -26.38800 10.99800  -9.98900  1.000 47.28000 ? 151 ARG D CZ  1 
ATOM   4364 N NH1 . ARG D 1 150 ? -26.98100 11.72900  -10.92700 1.000 48.80000 ? 151 ARG D NH1 1 
ATOM   4365 N NH2 . ARG D 1 150 ? -25.27900 10.31700  -10.28300 1.000 49.80000 ? 151 ARG D NH2 1 
ATOM   4366 N N   . GLU D 1 151 ? -26.24800 13.42600  -2.56500  1.000 15.53000 ? 152 GLU D N   1 
ATOM   4367 C CA  . GLU D 1 151 ? -25.06800 13.76600  -1.74900  1.000 18.45000 ? 152 GLU D CA  1 
ATOM   4368 C C   . GLU D 1 151 ? -24.49200 12.53500  -1.05700  1.000 18.33000 ? 152 GLU D C   1 
ATOM   4369 O O   . GLU D 1 151 ? -23.29100 12.49400  -0.74600  1.000 16.37000 ? 152 GLU D O   1 
ATOM   4370 C CB  . GLU D 1 151 ? -25.43700 14.88600  -0.73500  1.000 16.15000 ? 152 GLU D CB  1 
ATOM   4371 C CG  . GLU D 1 151 ? -24.17100 15.66400  -0.13000  1.000 18.40000 ? 152 GLU D CG  1 
ATOM   4372 C CD  . GLU D 1 151 ? -23.29800 16.36000  -1.20300  1.000 23.85000 ? 152 GLU D CD  1 
ATOM   4373 O OE1 . GLU D 1 151 ? -23.79400 16.70200  -2.30000  1.000 19.79000 ? 152 GLU D OE1 1 
ATOM   4374 O OE2 . GLU D 1 151 ? -22.09500 16.58400  -0.93900  1.000 23.07000 ? 152 GLU D OE2 1 
ATOM   4375 N N   . ALA D 1 152 ? -25.30600 11.50500  -0.77600  1.000 16.91000 ? 153 ALA D N   1 
ATOM   4376 C CA  . ALA D 1 152 ? -24.69000 10.33600  -0.16300  1.000 18.35000 ? 153 ALA D CA  1 
ATOM   4377 C C   . ALA D 1 152 ? -23.56700 9.76400   -1.05600  1.000 18.25000 ? 153 ALA D C   1 
ATOM   4378 O O   . ALA D 1 152 ? -22.52700 9.32700   -0.53500  1.000 20.42000 ? 153 ALA D O   1 
ATOM   4379 C CB  . ALA D 1 152 ? -25.74000 9.28900   0.18900   1.000 18.21000 ? 153 ALA D CB  1 
ATOM   4380 N N   . GLU D 1 153 ? -23.69400 9.83000   -2.39500  1.000 18.47000 ? 154 GLU D N   1 
ATOM   4381 C CA  . GLU D 1 153 ? -22.58100 9.34100   -3.22400  1.000 18.19000 ? 154 GLU D CA  1 
ATOM   4382 C C   . GLU D 1 153 ? -21.30700 10.17500  -3.02600  1.000 21.43000 ? 154 GLU D C   1 
ATOM   4383 O O   . GLU D 1 153 ? -20.17700 9.64000   -3.05700  1.000 17.71000 ? 154 GLU D O   1 
ATOM   4384 C CB  . GLU D 1 153 ? -22.95700 9.33200   -4.71600  1.000 24.60000 ? 154 GLU D CB  1 
ATOM   4385 C CG  . GLU D 1 153 ? -24.08400 8.36900   -5.05100  1.000 36.34000 ? 154 GLU D CG  1 
ATOM   4386 C CD  . GLU D 1 153 ? -24.89500 8.76300   -6.29400  1.000 49.02000 ? 154 GLU D CD  1 
ATOM   4387 O OE1 . GLU D 1 153 ? -24.31200 9.27900   -7.31500  1.000 46.08000 ? 154 GLU D OE1 1 
ATOM   4388 O OE2 . GLU D 1 153 ? -26.13300 8.56100   -6.21200  1.000 45.07000 ? 154 GLU D OE2 1 
ATOM   4389 N N   . GLN D 1 154 ? -21.45700 11.49400  -2.91800  1.000 18.29000 ? 155 GLN D N   1 
ATOM   4390 C CA  . GLN D 1 154 ? -20.32800 12.35000  -2.57500  1.000 14.88000 ? 155 GLN D CA  1 
ATOM   4391 C C   . GLN D 1 154 ? -19.71600 11.96900  -1.22500  1.000 15.94000 ? 155 GLN D C   1 
ATOM   4392 O O   . GLN D 1 154 ? -18.48700 12.04400  -1.03600  1.000 18.17000 ? 155 GLN D O   1 
ATOM   4393 C CB  . GLN D 1 154 ? -20.78600 13.82400  -2.56400  1.000 16.06000 ? 155 GLN D CB  1 
ATOM   4394 C CG  . GLN D 1 154 ? -21.20000 14.40200  -3.90700  1.000 23.40000 ? 155 GLN D CG  1 
ATOM   4395 C CD  . GLN D 1 154 ? -20.09800 14.24100  -4.95500  1.000 39.07000 ? 155 GLN D CD  1 
ATOM   4396 O OE1 . GLN D 1 154 ? -19.01700 14.80600  -4.79700  1.000 45.67000 ? 155 GLN D OE1 1 
ATOM   4397 N NE2 . GLN D 1 154 ? -20.35500 13.43200  -6.01000  1.000 40.52000 ? 155 GLN D NE2 1 
ATOM   4398 N N   . TRP D 1 155 ? -20.54200 11.66900  -0.23000  1.000 13.38000 ? 156 TRP D N   1 
ATOM   4399 C CA  . TRP D 1 155 ? -19.96900 11.23700  1.04600   1.000 13.96000 ? 156 TRP D CA  1 
ATOM   4400 C C   . TRP D 1 155 ? -19.20300 9.94400   0.87200   1.000 16.56000 ? 156 TRP D C   1 
ATOM   4401 O O   . TRP D 1 155 ? -18.12200 9.74900   1.44000   1.000 13.35000 ? 156 TRP D O   1 
ATOM   4402 C CB  . TRP D 1 155 ? -21.09000 11.02900  2.10900   1.000 10.89000 ? 156 TRP D CB  1 
ATOM   4403 C CG  . TRP D 1 155 ? -21.40900 12.31800  2.81000   1.000 12.90000 ? 156 TRP D CG  1 
ATOM   4404 C CD1 . TRP D 1 155 ? -22.53100 13.13800  2.65200   1.000 11.95000 ? 156 TRP D CD1 1 
ATOM   4405 C CD2 . TRP D 1 155 ? -20.58300 12.96200  3.77100   1.000 12.55000 ? 156 TRP D CD2 1 
ATOM   4406 N NE1 . TRP D 1 155 ? -22.42100 14.24100  3.45900   1.000 13.00000 ? 156 TRP D NE1 1 
ATOM   4407 C CE2 . TRP D 1 155 ? -21.24300 14.16700  4.15300   1.000 12.20000 ? 156 TRP D CE2 1 
ATOM   4408 C CE3 . TRP D 1 155 ? -19.31900 12.67300  4.30300   1.000 11.67000 ? 156 TRP D CE3 1 
ATOM   4409 C CZ2 . TRP D 1 155 ? -20.68100 15.07500  5.06700   1.000 14.04000 ? 156 TRP D CZ2 1 
ATOM   4410 C CZ3 . TRP D 1 155 ? -18.74900 13.58500  5.25500   1.000 9.58000  ? 156 TRP D CZ3 1 
ATOM   4411 C CH2 . TRP D 1 155 ? -19.45500 14.75000  5.62200   1.000 13.13000 ? 156 TRP D CH2 1 
ATOM   4412 N N   . ARG D 1 156 ? -19.79500 8.98700   0.16200   1.000 16.40000 ? 157 ARG D N   1 
ATOM   4413 C CA  . ARG D 1 156 ? -19.09600 7.72000   -0.01500  1.000 18.84000 ? 157 ARG D CA  1 
ATOM   4414 C C   . ARG D 1 156 ? -17.75000 7.94400   -0.70300  1.000 19.08000 ? 157 ARG D C   1 
ATOM   4415 O O   . ARG D 1 156 ? -16.70900 7.37700   -0.29300  1.000 20.29000 ? 157 ARG D O   1 
ATOM   4416 C CB  . ARG D 1 156 ? -20.01100 6.76000   -0.79600  1.000 19.13000 ? 157 ARG D CB  1 
ATOM   4417 C CG  . ARG D 1 156 ? -19.84100 5.26500   -0.52100  1.000 32.55000 ? 157 ARG D CG  1 
ATOM   4418 C CD  . ARG D 1 156 ? -21.11400 4.43000   -0.97600  1.000 33.57000 ? 157 ARG D CD  1 
ATOM   4419 N NE  . ARG D 1 156 ? -21.63700 4.75800   -2.30000  1.000 44.65000 ? 157 ARG D NE  1 
ATOM   4420 C CZ  . ARG D 1 156 ? -22.78500 5.38700   -2.59100  1.000 44.96000 ? 157 ARG D CZ  1 
ATOM   4421 N NH1 . ARG D 1 156 ? -23.54000 5.99900   -1.65500  1.000 26.35000 ? 157 ARG D NH1 1 
ATOM   4422 N NH2 . ARG D 1 156 ? -23.19600 5.40500   -3.86200  1.000 45.66000 ? 157 ARG D NH2 1 
ATOM   4423 N N   . ALA D 1 157 ? -17.73300 8.80900   -1.71800  1.000 17.71000 ? 158 ALA D N   1 
ATOM   4424 C CA  . ALA D 1 157 ? -16.49800 9.06600   -2.45700  1.000 18.34000 ? 158 ALA D CA  1 
ATOM   4425 C C   . ALA D 1 157 ? -15.44700 9.70100   -1.54800  1.000 21.78000 ? 158 ALA D C   1 
ATOM   4426 O O   . ALA D 1 157 ? -14.24300 9.40100   -1.63700  1.000 15.67000 ? 158 ALA D O   1 
ATOM   4427 C CB  . ALA D 1 157 ? -16.78600 9.96700   -3.64200  1.000 20.68000 ? 158 ALA D CB  1 
ATOM   4428 N N   . TYR D 1 158 ? -15.89800 10.58700  -0.65800  1.000 15.60000 ? 159 TYR D N   1 
ATOM   4429 C CA  . TYR D 1 158 ? -14.97500 11.25900  0.25400   1.000 15.10000 ? 159 TYR D CA  1 
ATOM   4430 C C   . TYR D 1 158 ? -14.46000 10.28100  1.29400   1.000 13.59000 ? 159 TYR D C   1 
ATOM   4431 O O   . TYR D 1 158 ? -13.24700 10.17700  1.52400   1.000 13.80000 ? 159 TYR D O   1 
ATOM   4432 C CB  . TYR D 1 158 ? -15.65900 12.46000  0.93900   1.000 12.33000 ? 159 TYR D CB  1 
ATOM   4433 C CG  . TYR D 1 158 ? -14.78700 13.06500  2.10500   1.000 13.89000 ? 159 TYR D CG  1 
ATOM   4434 C CD1 . TYR D 1 158 ? -13.71900 13.93000  1.82600   1.000 14.27000 ? 159 TYR D CD1 1 
ATOM   4435 C CD2 . TYR D 1 158 ? -15.02800 12.71300  3.43700   1.000 12.13000 ? 159 TYR D CD2 1 
ATOM   4436 C CE1 . TYR D 1 158 ? -12.94900 14.46400  2.88200   1.000 12.35000 ? 159 TYR D CE1 1 
ATOM   4437 C CE2 . TYR D 1 158 ? -14.28800 13.27300  4.51200   1.000 11.34000 ? 159 TYR D CE2 1 
ATOM   4438 C CZ  . TYR D 1 158 ? -13.25100 14.10600  4.22000   1.000 12.34000 ? 159 TYR D CZ  1 
ATOM   4439 O OH  . TYR D 1 158 ? -12.52700 14.59000  5.28400   1.000 11.62000 ? 159 TYR D OH  1 
ATOM   4440 N N   . LEU D 1 159 ? -15.36300 9.54500   1.92500   1.000 13.57000 ? 160 LEU D N   1 
ATOM   4441 C CA  . LEU D 1 159 ? -14.97300 8.69400   3.05200   1.000 11.29000 ? 160 LEU D CA  1 
ATOM   4442 C C   . LEU D 1 159 ? -14.13500 7.49200   2.59900   1.000 15.84000 ? 160 LEU D C   1 
ATOM   4443 O O   . LEU D 1 159 ? -13.16400 7.12500   3.24700   1.000 13.35000 ? 160 LEU D O   1 
ATOM   4444 C CB  . LEU D 1 159 ? -16.21800 8.20700   3.76700   1.000 9.60000  ? 160 LEU D CB  1 
ATOM   4445 C CG  . LEU D 1 159 ? -17.05300 9.31700   4.43600   1.000 11.49000 ? 160 LEU D CG  1 
ATOM   4446 C CD1 . LEU D 1 159 ? -18.46600 8.76700   4.84100   1.000 11.01000 ? 160 LEU D CD1 1 
ATOM   4447 C CD2 . LEU D 1 159 ? -16.31200 9.91900   5.64500   1.000 13.76000 ? 160 LEU D CD2 1 
ATOM   4448 N N   . GLU D 1 160 ? -14.47400 6.89200   1.47900   1.000 13.88000 ? 161 GLU D N   1 
ATOM   4449 C CA  . GLU D 1 160 ? -13.69700 5.76900   0.98300   1.000 16.16000 ? 161 GLU D CA  1 
ATOM   4450 C C   . GLU D 1 160 ? -12.38200 6.17900   0.31500   1.000 20.30000 ? 161 GLU D C   1 
ATOM   4451 O O   . GLU D 1 160 ? -11.47600 5.34900   0.21900   1.000 18.02000 ? 161 GLU D O   1 
ATOM   4452 C CB  . GLU D 1 160 ? -14.53700 4.96300   -0.03400  1.000 15.41000 ? 161 GLU D CB  1 
ATOM   4453 C CG  . GLU D 1 160 ? -15.69500 4.20100   0.65900   1.000 14.19000 ? 161 GLU D CG  1 
ATOM   4454 C CD  . GLU D 1 160 ? -16.53900 3.38400   -0.33500  1.000 27.66000 ? 161 GLU D CD  1 
ATOM   4455 O OE1 . GLU D 1 160 ? -16.32800 3.56100   -1.55000  1.000 23.38000 ? 161 GLU D OE1 1 
ATOM   4456 O OE2 . GLU D 1 160 ? -17.40500 2.59800   0.11500   1.000 22.63000 ? 161 GLU D OE2 1 
ATOM   4457 N N   . GLY D 1 161 ? -12.27300 7.42100   -0.16900  1.000 17.95000 ? 162 GLY D N   1 
ATOM   4458 C CA  . GLY D 1 161 ? -11.12000 7.89700   -0.88400  1.000 17.75000 ? 162 GLY D CA  1 
ATOM   4459 C C   . GLY D 1 161 ? -10.37200 8.94800   -0.08600  1.000 18.78000 ? 162 GLY D C   1 
ATOM   4460 O O   . GLY D 1 161 ? -9.54400  8.61500   0.77700   1.000 14.92000 ? 162 GLY D O   1 
ATOM   4461 N N   . THR D 1 162 ? -10.67200 10.21600  -0.36800  1.000 14.24000 ? 163 THR D N   1 
ATOM   4462 C CA  . THR D 1 162 ? -9.92900  11.35200  0.21000   1.000 13.39000 ? 163 THR D CA  1 
ATOM   4463 C C   . THR D 1 162 ? -9.68100  11.15600  1.70800   1.000 14.36000 ? 163 THR D C   1 
ATOM   4464 O O   . THR D 1 162 ? -8.55400  11.30400  2.20700   1.000 13.96000 ? 163 THR D O   1 
ATOM   4465 C CB  . THR D 1 162 ? -10.77500 12.63800  -0.02300  1.000 17.82000 ? 163 THR D CB  1 
ATOM   4466 O OG1 . THR D 1 162 ? -11.04700 12.81400  -1.41700  1.000 20.91000 ? 163 THR D OG1 1 
ATOM   4467 C CG2 . THR D 1 162 ? -10.06600 13.83900  0.49900   1.000 17.65000 ? 163 THR D CG2 1 
ATOM   4468 N N   . CYS D 1 163 ? -10.73500 10.80700  2.46900   1.000 11.97000 ? 164 CYS D N   1 
ATOM   4469 C CA  . CYS D 1 163 ? -10.58300 10.79600  3.93600   1.000 13.25000 ? 164 CYS D CA  1 
ATOM   4470 C C   . CYS D 1 163 ? -9.49300  9.81900   4.38000   1.000 15.06000 ? 164 CYS D C   1 
ATOM   4471 O O   . CYS D 1 163 ? -8.54000  10.21200  5.06900   1.000 13.16000 ? 164 CYS D O   1 
ATOM   4472 C CB  . CYS D 1 163 ? -11.93000 10.48100  4.61700   1.000 12.82000 ? 164 CYS D CB  1 
ATOM   4473 S SG  . CYS D 1 163 ? -11.98000 10.75600  6.46400   1.000 15.39000 ? 164 CYS D SG  1 
ATOM   4474 N N   . VAL D 1 164 ? -9.57500  8.55400   3.95300   1.000 13.99000 ? 165 VAL D N   1 
ATOM   4475 C CA  . VAL D 1 164 ? -8.55600  7.59300   4.38600   1.000 12.43000 ? 165 VAL D CA  1 
ATOM   4476 C C   . VAL D 1 164 ? -7.22100  7.89600   3.75300   1.000 13.31000 ? 165 VAL D C   1 
ATOM   4477 O O   . VAL D 1 164 ? -6.16300  7.69300   4.37100   1.000 15.04000 ? 165 VAL D O   1 
ATOM   4478 C CB  . VAL D 1 164 ? -8.98500  6.13100   4.12400   1.000 18.78000 ? 165 VAL D CB  1 
ATOM   4479 C CG1 . VAL D 1 164 ? -10.04600 5.72000   5.17000   1.000 18.83000 ? 165 VAL D CG1 1 
ATOM   4480 C CG2 . VAL D 1 164 ? -9.53300  5.93300   2.79400   1.000 17.98000 ? 165 VAL D CG2 1 
ATOM   4481 N N   . GLU D 1 165 ? -7.20900  8.30300   2.48800   1.000 15.61000 ? 166 GLU D N   1 
ATOM   4482 C CA  . GLU D 1 165 ? -5.89600  8.55500   1.85700   1.000 14.60000 ? 166 GLU D CA  1 
ATOM   4483 C C   . GLU D 1 165 ? -5.14100  9.66300   2.58000   1.000 15.53000 ? 166 GLU D C   1 
ATOM   4484 O O   . GLU D 1 165 ? -3.92700  9.54100   2.84200   1.000 14.58000 ? 166 GLU D O   1 
ATOM   4485 C CB  . GLU D 1 165 ? -6.08300  8.92100   0.38500   1.000 15.73000 ? 166 GLU D CB  1 
ATOM   4486 C CG  . GLU D 1 165 ? -6.67700  7.73700   -0.31900  1.000 19.45000 ? 166 GLU D CG  1 
ATOM   4487 C CD  . GLU D 1 165 ? -7.29600  8.03700   -1.68900  1.000 32.68000 ? 166 GLU D CD  1 
ATOM   4488 O OE1 . GLU D 1 165 ? -7.27200  9.22300   -2.14100  1.000 37.56000 ? 166 GLU D OE1 1 
ATOM   4489 O OE2 . GLU D 1 165 ? -7.84500  7.06100   -2.27400  1.000 31.37000 ? 166 GLU D OE2 1 
ATOM   4490 N N   . TRP D 1 166 ? -5.84000  10.75900  2.91700   1.000 13.86000 ? 167 TRP D N   1 
ATOM   4491 C CA  . TRP D 1 166 ? -5.16800  11.83200  3.63800   1.000 13.42000 ? 167 TRP D CA  1 
ATOM   4492 C C   . TRP D 1 166 ? -4.89700  11.44400  5.08800   1.000 12.45000 ? 167 TRP D C   1 
ATOM   4493 O O   . TRP D 1 166 ? -3.84200  11.78300  5.61100   1.000 13.09000 ? 167 TRP D O   1 
ATOM   4494 C CB  . TRP D 1 166 ? -5.95600  13.15600  3.52200   1.000 10.76000 ? 167 TRP D CB  1 
ATOM   4495 C CG  . TRP D 1 166 ? -5.66300  13.71600  2.13900   1.000 15.03000 ? 167 TRP D CG  1 
ATOM   4496 C CD1 . TRP D 1 166 ? -6.26300  13.36700  0.97700   1.000 15.63000 ? 167 TRP D CD1 1 
ATOM   4497 C CD2 . TRP D 1 166 ? -4.60700  14.60300  1.79800   1.000 12.54000 ? 167 TRP D CD2 1 
ATOM   4498 N NE1 . TRP D 1 166 ? -5.70700  14.04100  -0.05800  1.000 16.05000 ? 167 TRP D NE1 1 
ATOM   4499 C CE2 . TRP D 1 166 ? -4.66000  14.78900  0.41600   1.000 17.85000 ? 167 TRP D CE2 1 
ATOM   4500 C CE3 . TRP D 1 166 ? -3.64200  15.28700  2.55100   1.000 16.34000 ? 167 TRP D CE3 1 
ATOM   4501 C CZ2 . TRP D 1 166 ? -3.78700  15.63300  -0.26100  1.000 21.64000 ? 167 TRP D CZ2 1 
ATOM   4502 C CZ3 . TRP D 1 166 ? -2.73600  16.15400  1.84800   1.000 17.99000 ? 167 TRP D CZ3 1 
ATOM   4503 C CH2 . TRP D 1 166 ? -2.85900  16.32000  0.48100   1.000 18.08000 ? 167 TRP D CH2 1 
ATOM   4504 N N   . LEU D 1 167 ? -5.74300  10.64400  5.71200   1.000 12.85000 ? 168 LEU D N   1 
ATOM   4505 C CA  . LEU D 1 167 ? -5.39900  10.17100  7.05600   1.000 13.10000 ? 168 LEU D CA  1 
ATOM   4506 C C   . LEU D 1 167 ? -4.10400  9.33900   7.04200   1.000 14.07000 ? 168 LEU D C   1 
ATOM   4507 O O   . LEU D 1 167 ? -3.23300  9.50700   7.90900   1.000 13.08000 ? 168 LEU D O   1 
ATOM   4508 C CB  . LEU D 1 167 ? -6.55500  9.33200   7.60200   1.000 10.72000 ? 168 LEU D CB  1 
ATOM   4509 C CG  . LEU D 1 167 ? -6.33500  8.45800   8.83500   1.000 10.73000 ? 168 LEU D CG  1 
ATOM   4510 C CD1 . LEU D 1 167 ? -5.89700  9.30400   10.02000  1.000 9.43000  ? 168 LEU D CD1 1 
ATOM   4511 C CD2 . LEU D 1 167 ? -7.54300  7.63800   9.22700   1.000 9.44000  ? 168 LEU D CD2 1 
ATOM   4512 N N   . ARG D 1 168 ? -3.93700  8.47100   6.03100   1.000 14.57000 ? 169 ARG D N   1 
ATOM   4513 C CA  . ARG D 1 168 ? -2.68700  7.70600   5.92900   1.000 13.14000 ? 169 ARG D CA  1 
ATOM   4514 C C   . ARG D 1 168 ? -1.48800  8.61800   5.68900   1.000 17.43000 ? 169 ARG D C   1 
ATOM   4515 O O   . ARG D 1 168 ? -0.38700  8.36800   6.21800   1.000 13.78000 ? 169 ARG D O   1 
ATOM   4516 C CB  . ARG D 1 168 ? -2.80000  6.65500   4.80200   1.000 13.65000 ? 169 ARG D CB  1 
ATOM   4517 C CG  . ARG D 1 168 ? -3.92600  5.63200   5.18200   1.000 14.69000 ? 169 ARG D CG  1 
ATOM   4518 C CD  . ARG D 1 168 ? -4.15700  4.55800   4.04500   1.000 16.00000 ? 169 ARG D CD  1 
ATOM   4519 N NE  . ARG D 1 168 ? -2.95000  3.77000   3.94400   1.000 22.05000 ? 169 ARG D NE  1 
ATOM   4520 C CZ  . ARG D 1 168 ? -2.07500  3.83100   2.95300   1.000 29.28000 ? 169 ARG D CZ  1 
ATOM   4521 N NH1 . ARG D 1 168 ? -2.32800  4.51000   1.84700   1.000 32.10000 ? 169 ARG D NH1 1 
ATOM   4522 N NH2 . ARG D 1 168 ? -0.89400  3.22800   3.10100   1.000 35.73000 ? 169 ARG D NH2 1 
ATOM   4523 N N   . ARG D 1 169 ? -1.66200  9.65200   4.87000   1.000 12.77000 ? 170 ARG D N   1 
ATOM   4524 C CA  . ARG D 1 169 ? -0.54300  10.58600  4.66600   1.000 14.15000 ? 170 ARG D CA  1 
ATOM   4525 C C   . ARG D 1 169 ? -0.16400  11.24400  5.97000   1.000 13.91000 ? 170 ARG D C   1 
ATOM   4526 O O   . ARG D 1 169 ? 1.02700   11.38100  6.30500   1.000 15.63000 ? 170 ARG D O   1 
ATOM   4527 C CB  . ARG D 1 169 ? -0.95100  11.67300  3.68400   1.000 12.80000 ? 170 ARG D CB  1 
ATOM   4528 C CG  . ARG D 1 169 ? 0.13900   12.76900  3.49600   1.000 20.09000 ? 170 ARG D CG  1 
ATOM   4529 C CD  . ARG D 1 169 ? -0.39100  13.78600  2.54000   1.000 20.56000 ? 170 ARG D CD  1 
ATOM   4530 N NE  . ARG D 1 169 ? 0.39200   14.98300  2.27100   1.000 22.65000 ? 170 ARG D NE  1 
ATOM   4531 C CZ  . ARG D 1 169 ? 0.82400   15.21900  1.03700   1.000 39.87000 ? 170 ARG D CZ  1 
ATOM   4532 N NH1 . ARG D 1 169 ? 0.68900   14.30600  0.08900   1.000 39.85000 ? 170 ARG D NH1 1 
ATOM   4533 N NH2 . ARG D 1 169 ? 1.39300   16.39300  0.74200   1.000 31.90000 ? 170 ARG D NH2 1 
ATOM   4534 N N   . TYR D 1 170 ? -1.16200  11.73000  6.70900   1.000 10.49000 ? 171 TYR D N   1 
ATOM   4535 C CA  . TYR D 1 170 ? -0.82600  12.38100  8.00600   1.000 11.11000 ? 171 TYR D CA  1 
ATOM   4536 C C   . TYR D 1 170 ? -0.16300  11.41400  8.97500   1.000 14.79000 ? 171 TYR D C   1 
ATOM   4537 O O   . TYR D 1 170 ? 0.77800   11.78700  9.73700   1.000 12.77000 ? 171 TYR D O   1 
ATOM   4538 C CB  . TYR D 1 170 ? -2.09200  12.92700  8.65700   1.000 10.90000 ? 171 TYR D CB  1 
ATOM   4539 C CG  . TYR D 1 170 ? -2.83700  13.96100  7.82800   1.000 10.16000 ? 171 TYR D CG  1 
ATOM   4540 C CD1 . TYR D 1 170 ? -2.16600  14.83200  6.94500   1.000 10.28000 ? 171 TYR D CD1 1 
ATOM   4541 C CD2 . TYR D 1 170 ? -4.20200  14.09400  7.95700   1.000 11.83000 ? 171 TYR D CD2 1 
ATOM   4542 C CE1 . TYR D 1 170 ? -2.86600  15.80800  6.19400   1.000 13.29000 ? 171 TYR D CE1 1 
ATOM   4543 C CE2 . TYR D 1 170 ? -4.91900  15.05700  7.17800   1.000 13.92000 ? 171 TYR D CE2 1 
ATOM   4544 C CZ  . TYR D 1 170 ? -4.24800  15.90700  6.31900   1.000 12.81000 ? 171 TYR D CZ  1 
ATOM   4545 O OH  . TYR D 1 170 ? -5.00700  16.81900  5.60100   1.000 12.24000 ? 171 TYR D OH  1 
ATOM   4546 N N   . LEU D 1 171 ? -0.65700  10.17400  9.00200   1.000 11.08000 ? 172 LEU D N   1 
ATOM   4547 C CA  . LEU D 1 171 ? -0.07200  9.21600   9.94300   1.000 12.90000 ? 172 LEU D CA  1 
ATOM   4548 C C   . LEU D 1 171 ? 1.39700   8.98900   9.61400   1.000 14.64000 ? 172 LEU D C   1 
ATOM   4549 O O   . LEU D 1 171 ? 2.21400   8.74000   10.51400  1.000 16.19000 ? 172 LEU D O   1 
ATOM   4550 C CB  . LEU D 1 171 ? -0.83500  7.88600   9.92000   1.000 11.39000 ? 172 LEU D CB  1 
ATOM   4551 C CG  . LEU D 1 171 ? -2.25900  7.95300   10.53700  1.000 11.87000 ? 172 LEU D CG  1 
ATOM   4552 C CD1 . LEU D 1 171 ? -3.12200  6.74300   10.09900  1.000 11.89000 ? 172 LEU D CD1 1 
ATOM   4553 C CD2 . LEU D 1 171 ? -2.08400  7.96300   12.10700  1.000 14.17000 ? 172 LEU D CD2 1 
ATOM   4554 N N   . GLU D 1 172 ? 1.73600   9.04000   8.35000   1.000 14.59000 ? 173 GLU D N   1 
ATOM   4555 C CA  . GLU D 1 172 ? 3.11800   8.80600   7.93500   1.000 15.79000 ? 173 GLU D CA  1 
ATOM   4556 C C   . GLU D 1 172 ? 3.97600   10.03300  8.24900   1.000 15.79000 ? 173 GLU D C   1 
ATOM   4557 O O   . GLU D 1 172 ? 5.03100   9.92400   8.90000   1.000 14.48000 ? 173 GLU D O   1 
ATOM   4558 C CB  . GLU D 1 172 ? 3.12800   8.44400   6.43900   1.000 21.85000 ? 173 GLU D CB  1 
ATOM   4559 C CG  . GLU D 1 172 ? 4.52400   8.27300   5.78300   1.000 20.13000 ? 173 GLU D CG  1 
ATOM   4560 C CD  . GLU D 1 172 ? 5.40900   7.23000   6.51900   1.000 26.40000 ? 173 GLU D CD  1 
ATOM   4561 O OE1 . GLU D 1 172 ? 4.87700   6.25000   7.11900   1.000 23.85000 ? 173 GLU D OE1 1 
ATOM   4562 O OE2 . GLU D 1 172 ? 6.65200   7.43300   6.53700   1.000 30.85000 ? 173 GLU D OE2 1 
ATOM   4563 N N   . ASN D 1 173 ? 3.52000   11.21600  7.82400   1.000 13.86000 ? 174 ASN D N   1 
ATOM   4564 C CA  . ASN D 1 173 ? 4.24800   12.43700  8.12100   1.000 18.33000 ? 174 ASN D CA  1 
ATOM   4565 C C   . ASN D 1 173 ? 4.39800   12.66000  9.62800   1.000 20.88000 ? 174 ASN D C   1 
ATOM   4566 O O   . ASN D 1 173 ? 5.42800   13.20700  10.09200  1.000 16.77000 ? 174 ASN D O   1 
ATOM   4567 C CB  . ASN D 1 173 ? 3.55400   13.60800  7.43900   1.000 18.20000 ? 174 ASN D CB  1 
ATOM   4568 C CG  . ASN D 1 173 ? 3.63000   13.52500  5.91300   1.000 22.11000 ? 174 ASN D CG  1 
ATOM   4569 O OD1 . ASN D 1 173 ? 4.41800   12.74700  5.32500   1.000 30.20000 ? 174 ASN D OD1 1 
ATOM   4570 N ND2 . ASN D 1 173 ? 2.84300   14.34000  5.26100   1.000 23.53000 ? 174 ASN D ND2 1 
ATOM   4571 N N   . GLY D 1 174 ? 3.40500   12.21600  10.41300  1.000 14.79000 ? 175 GLY D N   1 
ATOM   4572 C CA  . GLY D 1 174 ? 3.40900   12.45800  11.83400  1.000 16.63000 ? 175 GLY D CA  1 
ATOM   4573 C C   . GLY D 1 174 ? 3.78500   11.22500  12.61900  1.000 13.05000 ? 175 GLY D C   1 
ATOM   4574 O O   . GLY D 1 174 ? 3.50000   11.14800  13.80200  1.000 17.81000 ? 175 GLY D O   1 
ATOM   4575 N N   . LYS D 1 175 ? 4.42500   10.24900  11.97500  1.000 15.26000 ? 176 LYS D N   1 
ATOM   4576 C CA  . LYS D 1 175 ? 4.47200   8.91500   12.57100  1.000 16.47000 ? 176 LYS D CA  1 
ATOM   4577 C C   . LYS D 1 175 ? 5.21200   8.88200   13.89700  1.000 18.62000 ? 176 LYS D C   1 
ATOM   4578 O O   . LYS D 1 175 ? 4.84800   8.07900   14.76500  1.000 14.81000 ? 176 LYS D O   1 
ATOM   4579 C CB  . LYS D 1 175 ? 5.10000   7.91600   11.59000  1.000 20.30000 ? 176 LYS D CB  1 
ATOM   4580 C CG  . LYS D 1 175 ? 6.54500   8.07800   11.34200  1.000 20.27000 ? 176 LYS D CG  1 
ATOM   4581 C CD  . LYS D 1 175 ? 7.03400   6.96800   10.36500  1.000 26.74000 ? 176 LYS D CD  1 
ATOM   4582 C CE  . LYS D 1 175 ? 8.35600   7.35100   9.68700   1.000 40.29000 ? 176 LYS D CE  1 
ATOM   4583 N NZ  . LYS D 1 175 ? 8.83100   6.39700   8.58300   1.000 40.28000 ? 176 LYS D NZ  1 
ATOM   4584 N N   . GLU D 1 176 ? 6.19000   9.77700   14.10200  1.000 15.89000 ? 177 GLU D N   1 
ATOM   4585 C CA  . GLU D 1 176 ? 6.96400   9.76400   15.34300  1.000 22.96000 ? 177 GLU D CA  1 
ATOM   4586 C C   . GLU D 1 176 ? 6.13600   10.15300  16.56200  1.000 25.79000 ? 177 GLU D C   1 
ATOM   4587 O O   . GLU D 1 176 ? 6.51100   9.80700   17.69500  1.000 19.34000 ? 177 GLU D O   1 
ATOM   4588 C CB  . GLU D 1 176 ? 8.17500   10.69800  15.22300  1.000 19.72000 ? 177 GLU D CB  1 
ATOM   4589 C CG  . GLU D 1 176 ? 9.15900   10.26700  14.12600  1.000 32.64000 ? 177 GLU D CG  1 
ATOM   4590 C CD  . GLU D 1 176 ? 9.67300   8.82800   14.32100  1.000 42.64000 ? 177 GLU D CD  1 
ATOM   4591 O OE1 . GLU D 1 176 ? 9.84200   8.40600   15.50200  1.000 40.03000 ? 177 GLU D OE1 1 
ATOM   4592 O OE2 . GLU D 1 176 ? 9.92700   8.12500   13.29700  1.000 47.14000 ? 177 GLU D OE2 1 
ATOM   4593 N N   . THR D 1 177 ? 5.02300   10.86200  16.38100  1.000 20.10000 ? 178 THR D N   1 
ATOM   4594 C CA  . THR D 1 177 ? 4.15200   11.13800  17.51900  1.000 15.81000 ? 178 THR D CA  1 
ATOM   4595 C C   . THR D 1 177 ? 2.80800   10.43500  17.39700  1.000 20.08000 ? 178 THR D C   1 
ATOM   4596 O O   . THR D 1 177 ? 2.30200   9.86300   18.35700  1.000 21.13000 ? 178 THR D O   1 
ATOM   4597 C CB  . THR D 1 177 ? 3.92000   12.65100  17.63100  1.000 23.73000 ? 178 THR D CB  1 
ATOM   4598 O OG1 . THR D 1 177 ? 3.50400   13.15500  16.35200  1.000 20.70000 ? 178 THR D OG1 1 
ATOM   4599 C CG2 . THR D 1 177 ? 5.21800   13.39500  18.03600  1.000 24.51000 ? 178 THR D CG2 1 
ATOM   4600 N N   . LEU D 1 178 ? 2.20600   10.44700  16.21300  1.000 13.27000 ? 179 LEU D N   1 
ATOM   4601 C CA  . LEU D 1 178 ? 0.87400   9.85400   16.08300  1.000 12.72000 ? 179 LEU D CA  1 
ATOM   4602 C C   . LEU D 1 178 ? 0.88400   8.34400   16.22400  1.000 17.45000 ? 179 LEU D C   1 
ATOM   4603 O O   . LEU D 1 178 ? -0.12600  7.77200   16.64700  1.000 17.79000 ? 179 LEU D O   1 
ATOM   4604 C CB  . LEU D 1 178 ? 0.28100   10.17900  14.70800  1.000 12.05000 ? 179 LEU D CB  1 
ATOM   4605 C CG  . LEU D 1 178 ? 0.05200   11.65500  14.44800  1.000 13.06000 ? 179 LEU D CG  1 
ATOM   4606 C CD1 . LEU D 1 178 ? -0.49800  11.84300  12.97000  1.000 12.37000 ? 179 LEU D CD1 1 
ATOM   4607 C CD2 . LEU D 1 178 ? -0.92000  12.16600  15.46000  1.000 14.09000 ? 179 LEU D CD2 1 
ATOM   4608 N N   . GLN D 1 179 ? 1.95400   7.66900   15.78000  1.000 14.20000 ? 180 GLN D N   1 
ATOM   4609 C CA  . GLN D 1 179 ? 1.97800   6.21000   15.83400  1.000 13.68000 ? 180 GLN D CA  1 
ATOM   4610 C C   . GLN D 1 179 ? 2.77500   5.67400   17.02100  1.000 18.43000 ? 180 GLN D C   1 
ATOM   4611 O O   . GLN D 1 179 ? 3.17000   4.51500   17.02400  1.000 24.88000 ? 180 GLN D O   1 
ATOM   4612 C CB  . GLN D 1 179 ? 2.52800   5.63100   14.53200  1.000 15.02000 ? 180 GLN D CB  1 
ATOM   4613 C CG  . GLN D 1 179 ? 1.74000   6.19000   13.27300  1.000 18.23000 ? 180 GLN D CG  1 
ATOM   4614 C CD  . GLN D 1 179 ? 1.91600   5.32900   12.05400  1.000 18.63000 ? 180 GLN D CD  1 
ATOM   4615 O OE1 . GLN D 1 179 ? 1.75300   4.11000   12.11700  1.000 22.50000 ? 180 GLN D OE1 1 
ATOM   4616 N NE2 . GLN D 1 179 ? 2.25600   5.94900   10.93800  1.000 17.86000 ? 180 GLN D NE2 1 
ATOM   4617 N N   . ARG D 1 180 ? 2.99900   6.46600   18.02800  1.000 15.92000 ? 181 ARG D N   1 
ATOM   4618 C CA  . ARG D 1 180 ? 3.74900   6.03700   19.20800  1.000 21.21000 ? 181 ARG D CA  1 
ATOM   4619 C C   . ARG D 1 180 ? 2.84600   6.25900   20.43200  1.000 24.16000 ? 181 ARG D C   1 
ATOM   4620 O O   . ARG D 1 180 ? 2.59700   7.41800   20.79500  1.000 27.21000 ? 181 ARG D O   1 
ATOM   4621 C CB  . ARG D 1 180 ? 5.00700   6.89400   19.35500  1.000 22.67000 ? 181 ARG D CB  1 
ATOM   4622 C CG  . ARG D 1 180 ? 5.55800   6.88900   20.75400  1.000 40.40000 ? 181 ARG D CG  1 
ATOM   4623 C CD  . ARG D 1 180 ? 6.57900   7.99200   20.96500  1.000 51.93000 ? 181 ARG D CD  1 
ATOM   4624 N NE  . ARG D 1 180 ? 5.98200   9.32500   20.86700  1.000 50.01000 ? 181 ARG D NE  1 
ATOM   4625 C CZ  . ARG D 1 180 ? 6.44200   10.39200  21.51200  1.000 53.25000 ? 181 ARG D CZ  1 
ATOM   4626 N NH1 . ARG D 1 180 ? 7.56800   10.33900  22.21600  1.000 63.27000 ? 181 ARG D NH1 1 
ATOM   4627 N NH2 . ARG D 1 180 ? 5.77100   11.54200  21.43300  1.000 46.77000 ? 181 ARG D NH2 1 
ATOM   4628 N N   . ALA D 1 181 ? 2.34300   5.19600   21.06900  1.000 16.22000 ? 182 ALA D N   1 
ATOM   4629 C CA  . ALA D 1 181 ? 1.60800   5.42300   22.32600  1.000 16.97000 ? 182 ALA D CA  1 
ATOM   4630 C C   . ALA D 1 181 ? 2.56900   5.84800   23.44400  1.000 21.99000 ? 182 ALA D C   1 
ATOM   4631 O O   . ALA D 1 181 ? 3.76800   5.50800   23.43800  1.000 19.76000 ? 182 ALA D O   1 
ATOM   4632 C CB  . ALA D 1 181 ? 0.87200   4.17500   22.78700  1.000 19.97000 ? 182 ALA D CB  1 
ATOM   4633 N N   . GLU D 1 182 ? 2.03600   6.59400   24.41900  1.000 15.31000 ? 183 GLU D N   1 
ATOM   4634 C CA  . GLU D 1 182 ? 2.81800   6.96500   25.59900  1.000 14.79000 ? 183 GLU D CA  1 
ATOM   4635 C C   . GLU D 1 182 ? 2.11000   6.38100   26.79300  1.000 11.95000 ? 183 GLU D C   1 
ATOM   4636 O O   . GLU D 1 182 ? 0.96000   6.72000   27.04700  1.000 10.10000 ? 183 GLU D O   1 
ATOM   4637 C CB  . GLU D 1 182 ? 2.97400   8.48100   25.74200  1.000 13.51000 ? 183 GLU D CB  1 
ATOM   4638 C CG  . GLU D 1 182 ? 3.83400   9.18200   24.66200  1.000 24.55000 ? 183 GLU D CG  1 
ATOM   4639 C CD  . GLU D 1 182 ? 4.36100   10.52500  25.15900  1.000 36.66000 ? 183 GLU D CD  1 
ATOM   4640 O OE1 . GLU D 1 182 ? 5.24200   10.52500  26.05800  1.000 23.27000 ? 183 GLU D OE1 1 
ATOM   4641 O OE2 . GLU D 1 182 ? 3.77500   11.58200  24.73300  1.000 23.55000 ? 183 GLU D OE2 1 
ATOM   4642 N N   . HIS D 1 183 ? 2.76000   5.44200   27.47000  1.000 12.84000 ? 184 HIS D N   1 
ATOM   4643 C CA  . HIS D 1 183 ? 2.04100   4.74600   28.53400  1.000 11.19000 ? 184 HIS D CA  1 
ATOM   4644 C C   . HIS D 1 183 ? 1.82500   5.69600   29.70800  1.000 12.07000 ? 184 HIS D C   1 
ATOM   4645 O O   . HIS D 1 183 ? 2.58900   6.64800   29.91200  1.000 10.39000 ? 184 HIS D O   1 
ATOM   4646 C CB  . HIS D 1 183 ? 2.79100   3.47000   28.98600  1.000 8.70000  ? 184 HIS D CB  1 
ATOM   4647 C CG  . HIS D 1 183 ? 4.05800   3.77100   29.74600  1.000 15.67000 ? 184 HIS D CG  1 
ATOM   4648 N ND1 . HIS D 1 183 ? 5.24900   4.05000   29.10400  1.000 16.07000 ? 184 HIS D ND1 1 
ATOM   4649 C CD2 . HIS D 1 183 ? 4.31700   3.86700   31.07500  1.000 13.69000 ? 184 HIS D CD2 1 
ATOM   4650 C CE1 . HIS D 1 183 ? 6.19600   4.27600   30.00600  1.000 17.94000 ? 184 HIS D CE1 1 
ATOM   4651 N NE2 . HIS D 1 183 ? 5.65000   4.19500   31.20800  1.000 16.36000 ? 184 HIS D NE2 1 
ATOM   4652 N N   . PRO D 1 184 ? 0.77600   5.46700   30.50400  1.000 10.27000 ? 185 PRO D N   1 
ATOM   4653 C CA  . PRO D 1 184 ? 0.51600   6.35200   31.62300  1.000 9.88000  ? 185 PRO D CA  1 
ATOM   4654 C C   . PRO D 1 184 ? 1.59700   6.22300   32.68800  1.000 12.16000 ? 185 PRO D C   1 
ATOM   4655 O O   . PRO D 1 184 ? 2.02000   5.12000   33.00000  1.000 11.75000 ? 185 PRO D O   1 
ATOM   4656 C CB  . PRO D 1 184 ? -0.82300  5.86200   32.18200  1.000 9.53000  ? 185 PRO D CB  1 
ATOM   4657 C CG  . PRO D 1 184 ? -0.88900  4.37100   31.74400  1.000 12.99000 ? 185 PRO D CG  1 
ATOM   4658 C CD  . PRO D 1 184 ? -0.25400  4.42300   30.33200  1.000 14.39000 ? 185 PRO D CD  1 
ATOM   4659 N N   . LYS D 1 185 ? 1.98600   7.34700   33.27100  1.000 10.00000 ? 186 LYS D N   1 
ATOM   4660 C CA  . LYS D 1 185 ? 2.86500   7.33400   34.44100  1.000 10.60000 ? 186 LYS D CA  1 
ATOM   4661 C C   . LYS D 1 185 ? 1.93300   7.23200   35.63500  1.000 10.94000 ? 186 LYS D C   1 
ATOM   4662 O O   . LYS D 1 185 ? 1.08200   8.08900   35.79200  1.000 10.74000 ? 186 LYS D O   1 
ATOM   4663 C CB  . LYS D 1 185 ? 3.70100   8.59400   34.52500  1.000 9.14000  ? 186 LYS D CB  1 
ATOM   4664 C CG  . LYS D 1 185 ? 4.42900   8.98800   33.14000  1.000 12.00000 ? 186 LYS D CG  1 
ATOM   4665 C CD  . LYS D 1 185 ? 5.16000   7.76900   32.57200  1.000 17.76000 ? 186 LYS D CD  1 
ATOM   4666 C CE  . LYS D 1 185 ? 5.85700   7.98100   31.18700  1.000 14.32000 ? 186 LYS D CE  1 
ATOM   4667 N NZ  . LYS D 1 185 ? 4.83100   8.31400   30.14200  1.000 16.11000 ? 186 LYS D NZ  1 
ATOM   4668 N N   . THR D 1 186 ? 2.08000   6.19100   36.47200  1.000 12.58000 ? 187 THR D N   1 
ATOM   4669 C CA  . THR D 1 186 ? 1.03700   5.92200   37.47300  1.000 10.73000 ? 187 THR D CA  1 
ATOM   4670 C C   . THR D 1 186 ? 1.58900   6.03500   38.88900  1.000 14.87000 ? 187 THR D C   1 
ATOM   4671 O O   . THR D 1 186 ? 2.78300   5.79000   39.13300  1.000 12.08000 ? 187 THR D O   1 
ATOM   4672 C CB  . THR D 1 186 ? 0.42700   4.52100   37.26500  1.000 15.23000 ? 187 THR D CB  1 
ATOM   4673 O OG1 . THR D 1 186 ? 1.48100   3.52000   37.27900  1.000 13.97000 ? 187 THR D OG1 1 
ATOM   4674 C CG2 . THR D 1 186 ? -0.23600  4.43800   35.89300  1.000 9.93000  ? 187 THR D CG2 1 
ATOM   4675 N N   . HIS D 1 187 ? 0.70700   6.40800   39.81400  1.000 10.70000 ? 188 HIS D N   1 
ATOM   4676 C CA  . HIS D 1 187 ? 1.02300   6.26600   41.21200  1.000 16.89000 ? 188 HIS D CA  1 
ATOM   4677 C C   . HIS D 1 187 ? -0.28700  6.29100   41.99500  1.000 13.12000 ? 188 HIS D C   1 
ATOM   4678 O O   . HIS D 1 187 ? -1.38900  6.54800   41.45600  1.000 14.70000 ? 188 HIS D O   1 
ATOM   4679 C CB  . HIS D 1 187 ? 1.92700   7.36500   41.74000  1.000 18.49000 ? 188 HIS D CB  1 
ATOM   4680 C CG  . HIS D 1 187 ? 1.43600   8.74200   41.50000  1.000 21.98000 ? 188 HIS D CG  1 
ATOM   4681 N ND1 . HIS D 1 187 ? 1.58000   9.40700   40.30500  1.000 20.93000 ? 188 HIS D ND1 1 
ATOM   4682 C CD2 . HIS D 1 187 ? 0.91900   9.64800   42.38000  1.000 24.89000 ? 188 HIS D CD2 1 
ATOM   4683 C CE1 . HIS D 1 187 ? 1.07800   10.63400  40.42500  1.000 37.12000 ? 188 HIS D CE1 1 
ATOM   4684 N NE2 . HIS D 1 187 ? 0.68600   10.81700  41.67900  1.000 29.41000 ? 188 HIS D NE2 1 
ATOM   4685 N N   . VAL D 1 188 ? -0.15500  5.96800   43.27600  1.000 11.65000 ? 189 VAL D N   1 
ATOM   4686 C CA  . VAL D 1 188 ? -1.25300  5.98400   44.23600  1.000 11.72000 ? 189 VAL D CA  1 
ATOM   4687 C C   . VAL D 1 188 ? -0.92700  7.01500   45.31500  1.000 14.35000 ? 189 VAL D C   1 
ATOM   4688 O O   . VAL D 1 188 ? 0.19100   7.01200   45.84700  1.000 11.91000 ? 189 VAL D O   1 
ATOM   4689 C CB  . VAL D 1 188 ? -1.42400  4.58600   44.86300  1.000 13.34000 ? 189 VAL D CB  1 
ATOM   4690 C CG1 . VAL D 1 188 ? -2.56700  4.59700   45.90500  1.000 9.09000  ? 189 VAL D CG1 1 
ATOM   4691 C CG2 . VAL D 1 188 ? -1.72100  3.53800   43.80900  1.000 16.76000 ? 189 VAL D CG2 1 
ATOM   4692 N N   . THR D 1 189 ? -1.89500  7.86300   45.68600  1.000 10.86000 ? 190 THR D N   1 
ATOM   4693 C CA  . THR D 1 189 ? -1.69900  8.76600   46.80600  1.000 10.17000 ? 190 THR D CA  1 
ATOM   4694 C C   . THR D 1 189 ? -2.75900  8.44600   47.86400  1.000 14.21000 ? 190 THR D C   1 
ATOM   4695 O O   . THR D 1 189 ? -3.75700  7.78000   47.58300  1.000 13.26000 ? 190 THR D O   1 
ATOM   4696 C CB  . THR D 1 189 ? -1.78900  10.24200  46.39200  1.000 15.46000 ? 190 THR D CB  1 
ATOM   4697 O OG1 . THR D 1 189 ? -3.02900  10.47500  45.70500  1.000 13.15000 ? 190 THR D OG1 1 
ATOM   4698 C CG2 . THR D 1 189 ? -0.60700  10.64000  45.44500  1.000 12.62000 ? 190 THR D CG2 1 
ATOM   4699 N N   . HIS D 1 190 ? -2.55600  8.96200   49.06900  1.000 14.94000 ? 191 HIS D N   1 
ATOM   4700 C CA  . HIS D 1 190 ? -3.32400  8.58800   50.26000  1.000 15.15000 ? 191 HIS D CA  1 
ATOM   4701 C C   . HIS D 1 190 ? -3.70200  9.87800   50.98200  1.000 17.47000 ? 191 HIS D C   1 
ATOM   4702 O O   . HIS D 1 190 ? -2.82700  10.70000  51.24500  1.000 17.45000 ? 191 HIS D O   1 
ATOM   4703 C CB  . HIS D 1 190 ? -2.44400  7.64200   51.14700  1.000 16.46000 ? 191 HIS D CB  1 
ATOM   4704 C CG  . HIS D 1 190 ? -3.12000  7.13200   52.38900  1.000 21.01000 ? 191 HIS D CG  1 
ATOM   4705 N ND1 . HIS D 1 190 ? -3.15600  7.85400   53.56300  1.000 19.76000 ? 191 HIS D ND1 1 
ATOM   4706 C CD2 . HIS D 1 190 ? -3.76800  5.97100   52.64300  1.000 18.07000 ? 191 HIS D CD2 1 
ATOM   4707 C CE1 . HIS D 1 190 ? -3.81800  7.16300   54.48300  1.000 25.01000 ? 191 HIS D CE1 1 
ATOM   4708 N NE2 . HIS D 1 190 ? -4.17700  6.00400   53.95700  1.000 18.14000 ? 191 HIS D NE2 1 
ATOM   4709 N N   . HIS D 1 191 ? -4.99300  10.04500  51.30500  1.000 14.02000 ? 192 HIS D N   1 
ATOM   4710 C CA  . HIS D 1 191 ? -5.54200  11.29100  51.83000  1.000 18.71000 ? 192 HIS D CA  1 
ATOM   4711 C C   . HIS D 1 191 ? -6.50100  10.94300  52.95500  1.000 19.51000 ? 192 HIS D C   1 
ATOM   4712 O O   . HIS D 1 191 ? -7.66800  10.64700  52.70500  1.000 20.86000 ? 192 HIS D O   1 
ATOM   4713 C CB  . HIS D 1 191 ? -6.27800  12.06800  50.73000  1.000 18.86000 ? 192 HIS D CB  1 
ATOM   4714 C CG  . HIS D 1 191 ? -5.47100  12.21600  49.47800  1.000 22.00000 ? 192 HIS D CG  1 
ATOM   4715 N ND1 . HIS D 1 191 ? -4.54900  13.23100  49.32100  1.000 21.53000 ? 192 HIS D ND1 1 
ATOM   4716 C CD2 . HIS D 1 191 ? -5.35800  11.43000  48.38400  1.000 19.18000 ? 192 HIS D CD2 1 
ATOM   4717 C CE1 . HIS D 1 191 ? -3.95900  13.11000  48.14600  1.000 22.19000 ? 192 HIS D CE1 1 
ATOM   4718 N NE2 . HIS D 1 191 ? -4.40900  12.01000  47.56500  1.000 18.00000 ? 192 HIS D NE2 1 
ATOM   4719 N N   . PRO D 1 192 ? -6.02800  10.91400  54.19700  1.000 26.18000 ? 193 PRO D N   1 
ATOM   4720 C CA  . PRO D 1 192 ? -6.94000  10.63800  55.32200  1.000 23.54000 ? 193 PRO D CA  1 
ATOM   4721 C C   . PRO D 1 192 ? -8.08700  11.62500  55.33000  1.000 24.85000 ? 193 PRO D C   1 
ATOM   4722 O O   . PRO D 1 192 ? -7.92300  12.80200  55.02800  1.000 27.38000 ? 193 PRO D O   1 
ATOM   4723 C CB  . PRO D 1 192 ? -6.05200  10.78100  56.56200  1.000 26.79000 ? 193 PRO D CB  1 
ATOM   4724 C CG  . PRO D 1 192 ? -4.59500  10.48400  56.03400  1.000 28.03000 ? 193 PRO D CG  1 
ATOM   4725 C CD  . PRO D 1 192 ? -4.62000  11.08300  54.61700  1.000 23.85000 ? 193 PRO D CD  1 
ATOM   4726 N N   . VAL D 1 193 ? -9.27600  11.10300  55.58900  1.000 27.46000 ? 194 VAL D N   1 
ATOM   4727 C CA  . VAL D 1 193 ? -10.47600 11.91300  55.68500  1.000 24.16000 ? 194 VAL D CA  1 
ATOM   4728 C C   . VAL D 1 193 ? -10.98200 12.00000  57.11000  1.000 32.72000 ? 194 VAL D C   1 
ATOM   4729 O O   . VAL D 1 193 ? -11.69400 12.96100  57.43000  1.000 29.28000 ? 194 VAL D O   1 
ATOM   4730 C CB  . VAL D 1 193 ? -11.59200 11.39900  54.74600  1.000 31.50000 ? 194 VAL D CB  1 
ATOM   4731 C CG1 . VAL D 1 193 ? -11.15800 11.45500  53.27600  1.000 26.24000 ? 194 VAL D CG1 1 
ATOM   4732 C CG2 . VAL D 1 193 ? -11.87500 10.03300  55.00500  1.000 31.69000 ? 194 VAL D CG2 1 
ATOM   4733 N N   . SER D 1 194 ? -10.59600 11.07000  57.98200  1.000 30.57000 ? 195 SER D N   1 
ATOM   4734 C CA  . SER D 1 194 ? -10.98900 11.06000  59.39200  1.000 32.11000 ? 195 SER D CA  1 
ATOM   4735 C C   . SER D 1 194 ? -10.11600 10.03100  60.07800  1.000 39.27000 ? 195 SER D C   1 
ATOM   4736 O O   . SER D 1 194 ? -9.26800  9.40200   59.44500  1.000 26.17000 ? 195 SER D O   1 
ATOM   4737 C CB  . SER D 1 194 ? -12.45900 10.71100  59.57000  1.000 30.36000 ? 195 SER D CB  1 
ATOM   4738 O OG  . SER D 1 194 ? -12.61100 9.31300   59.39900  1.000 31.20000 ? 195 SER D OG  1 
ATOM   4739 N N   . ASP D 1 195 ? -10.33900 9.83700   61.38600  1.000 35.51000 ? 196 ASP D N   1 
ATOM   4740 C CA  . ASP D 1 195 ? -9.54500  8.83100   62.07800  1.000 35.70000 ? 196 ASP D CA  1 
ATOM   4741 C C   . ASP D 1 195 ? -9.90000  7.45100   61.57700  1.000 37.22000 ? 196 ASP D C   1 
ATOM   4742 O O   . ASP D 1 195 ? -9.12400  6.51800   61.78600  1.000 40.11000 ? 196 ASP D O   1 
ATOM   4743 C CB  . ASP D 1 195 ? -9.76000  8.88300   63.60700  1.000 45.24000 ? 196 ASP D CB  1 
ATOM   4744 C CG  . ASP D 1 195 ? -8.94600  9.96900   64.27900  0.000 39.84000 ? 196 ASP D CG  1 
ATOM   4745 O OD1 . ASP D 1 195 ? -8.10200  10.59300  63.60200  0.000 39.32000 ? 196 ASP D OD1 1 
ATOM   4746 O OD2 . ASP D 1 195 ? -9.16400  10.21100  65.48600  0.000 40.11000 ? 196 ASP D OD2 1 
ATOM   4747 N N   . HIS D 1 196 ? -11.04600 7.32100   60.89400  1.000 30.12000 ? 197 HIS D N   1 
ATOM   4748 C CA  . HIS D 1 196 ? -11.57500 6.03100   60.51300  1.000 28.61000 ? 197 HIS D CA  1 
ATOM   4749 C C   . HIS D 1 196 ? -11.44800 5.69900   59.02600  1.000 30.28000 ? 197 HIS D C   1 
ATOM   4750 O O   . HIS D 1 196 ? -11.57700 4.52600   58.67200  1.000 25.23000 ? 197 HIS D O   1 
ATOM   4751 C CB  . HIS D 1 196 ? -13.05000 5.95500   60.92800  1.000 38.34000 ? 197 HIS D CB  1 
ATOM   4752 C CG  . HIS D 1 196 ? -13.25600 6.25600   62.38000  1.000 55.17000 ? 197 HIS D CG  1 
ATOM   4753 N ND1 . HIS D 1 196 ? -12.98800 5.33600   63.37700  1.000 64.29000 ? 197 HIS D ND1 1 
ATOM   4754 C CD2 . HIS D 1 196 ? -13.69600 7.37300   63.01000  1.000 60.42000 ? 197 HIS D CD2 1 
ATOM   4755 C CE1 . HIS D 1 196 ? -13.25400 5.87200   64.55600  1.000 61.69000 ? 197 HIS D CE1 1 
ATOM   4756 N NE2 . HIS D 1 196 ? -13.68900 7.10500   64.36200  1.000 68.97000 ? 197 HIS D NE2 1 
ATOM   4757 N N   . GLU D 1 197 ? -11.20000 6.68000   58.15300  1.000 27.35000 ? 198 GLU D N   1 
ATOM   4758 C CA  . GLU D 1 197 ? -11.25600 6.42700   56.70300  1.000 26.35000 ? 198 GLU D CA  1 
ATOM   4759 C C   . GLU D 1 197 ? -10.18900 7.24400   55.98800  1.000 23.78000 ? 198 GLU D C   1 
ATOM   4760 O O   . GLU D 1 197 ? -9.75800  8.28700   56.48400  1.000 19.61000 ? 198 GLU D O   1 
ATOM   4761 C CB  . GLU D 1 197 ? -12.60000 6.79100   56.08600  1.000 25.64000 ? 198 GLU D CB  1 
ATOM   4762 C CG  . GLU D 1 197 ? -13.66400 5.77800   56.39500  1.000 30.57000 ? 198 GLU D CG  1 
ATOM   4763 C CD  . GLU D 1 197 ? -15.01500 6.19600   55.88000  1.000 26.94000 ? 198 GLU D CD  1 
ATOM   4764 O OE1 . GLU D 1 197 ? -15.35900 7.37200   56.05300  1.000 29.69000 ? 198 GLU D OE1 1 
ATOM   4765 O OE2 . GLU D 1 197 ? -15.68500 5.33600   55.29600  1.000 35.99000 ? 198 GLU D OE2 1 
ATOM   4766 N N   . ALA D 1 198 ? -9.81000  6.76900   54.80100  1.000 23.40000 ? 199 ALA D N   1 
ATOM   4767 C CA  . ALA D 1 198 ? -8.86100  7.51000   53.96400  1.000 21.75000 ? 199 ALA D CA  1 
ATOM   4768 C C   . ALA D 1 198 ? -9.18300  7.28800   52.50600  1.000 18.72000 ? 199 ALA D C   1 
ATOM   4769 O O   . ALA D 1 198 ? -9.62600  6.20800   52.11100  1.000 20.51000 ? 199 ALA D O   1 
ATOM   4770 C CB  . ALA D 1 198 ? -7.39700  7.11100   54.20500  1.000 17.81000 ? 199 ALA D CB  1 
ATOM   4771 N N   . THR D 1 199 ? -8.87100  8.30100   51.69800  1.000 16.54000 ? 200 THR D N   1 
ATOM   4772 C CA  . THR D 1 199 ? -9.03900  8.19800   50.25600  1.000 16.42000 ? 200 THR D CA  1 
ATOM   4773 C C   . THR D 1 199 ? -7.77500  7.62600   49.67400  1.000 16.86000 ? 200 THR D C   1 
ATOM   4774 O O   . THR D 1 199 ? -6.69200  8.15100   49.94900  1.000 16.10000 ? 200 THR D O   1 
ATOM   4775 C CB  . THR D 1 199 ? -9.28800  9.56900   49.64100  1.000 18.56000 ? 200 THR D CB  1 
ATOM   4776 O OG1 . THR D 1 199 ? -10.45000 10.14700  50.26900  1.000 22.67000 ? 200 THR D OG1 1 
ATOM   4777 C CG2 . THR D 1 199 ? -9.45300  9.45800   48.07700  1.000 14.39000 ? 200 THR D CG2 1 
ATOM   4778 N N   . LEU D 1 200 ? -7.92700  6.59900   48.83500  1.000 16.01000 ? 201 LEU D N   1 
ATOM   4779 C CA  . LEU D 1 200 ? -6.84500  6.16000   47.94300  1.000 12.90000 ? 201 LEU D CA  1 
ATOM   4780 C C   . LEU D 1 200 ? -7.15900  6.66400   46.54700  1.000 13.06000 ? 201 LEU D C   1 
ATOM   4781 O O   . LEU D 1 200 ? -8.26700  6.45900   46.05300  1.000 13.40000 ? 201 LEU D O   1 
ATOM   4782 C CB  . LEU D 1 200 ? -6.73100  4.63900   47.93200  1.000 11.24000 ? 201 LEU D CB  1 
ATOM   4783 C CG  . LEU D 1 200 ? -6.25300  4.01500   49.25600  1.000 12.96000 ? 201 LEU D CG  1 
ATOM   4784 C CD1 . LEU D 1 200 ? -6.32600  2.48800   49.07200  1.000 17.46000 ? 201 LEU D CD1 1 
ATOM   4785 C CD2 . LEU D 1 200 ? -4.78300  4.36700   49.46100  1.000 16.96000 ? 201 LEU D CD2 1 
ATOM   4786 N N   . ARG D 1 201 ? -6.19800  7.36800   45.91400  1.000 14.52000 ? 202 ARG D N   1 
ATOM   4787 C CA  . ARG D 1 201 ? -6.43600  7.92800   44.58000  1.000 9.48000  ? 202 ARG D CA  1 
ATOM   4788 C C   . ARG D 1 201 ? -5.36900  7.34900   43.65600  1.000 13.24000 ? 202 ARG D C   1 
ATOM   4789 O O   . ARG D 1 201 ? -4.17300  7.40500   43.97400  1.000 10.22000 ? 202 ARG D O   1 
ATOM   4790 C CB  . ARG D 1 201 ? -6.37500  9.47200   44.62400  1.000 11.81000 ? 202 ARG D CB  1 
ATOM   4791 C CG  . ARG D 1 201 ? -6.63500  10.14400  43.20700  1.000 12.90000 ? 202 ARG D CG  1 
ATOM   4792 C CD  . ARG D 1 201 ? -6.82200  11.66500  43.37800  1.000 14.88000 ? 202 ARG D CD  1 
ATOM   4793 N NE  . ARG D 1 201 ? -8.14600  11.95500  43.93300  1.000 16.56000 ? 202 ARG D NE  1 
ATOM   4794 C CZ  . ARG D 1 201 ? -8.36700  12.45800  45.13400  1.000 18.07000 ? 202 ARG D CZ  1 
ATOM   4795 N NH1 . ARG D 1 201 ? -7.37100  12.79800  45.92500  1.000 15.92000 ? 202 ARG D NH1 1 
ATOM   4796 N NH2 . ARG D 1 201 ? -9.63100  12.57000  45.57200  1.000 19.38000 ? 202 ARG D NH2 1 
ATOM   4797 N N   . CYS D 1 202 ? -5.80400  6.71300   42.58600  1.000 10.60000 ? 203 CYS D N   1 
ATOM   4798 C CA  . CYS D 1 202 ? -4.88500  6.11300   41.61600  1.000 10.96000 ? 203 CYS D CA  1 
ATOM   4799 C C   . CYS D 1 202 ? -4.79400  7.04800   40.42100  1.000 13.48000 ? 203 CYS D C   1 
ATOM   4800 O O   . CYS D 1 202 ? -5.82500  7.40200   39.82600  1.000 12.33000 ? 203 CYS D O   1 
ATOM   4801 C CB  . CYS D 1 202 ? -5.41800  4.74300   41.24300  1.000 15.05000 ? 203 CYS D CB  1 
ATOM   4802 S SG  . CYS D 1 202 ? -4.43500  3.86500   40.07500  1.000 18.62000 ? 203 CYS D SG  1 
ATOM   4803 N N   . TRP D 1 203 ? -3.56900  7.48900   40.09700  1.000 9.78000  ? 204 TRP D N   1 
ATOM   4804 C CA  . TRP D 1 203 ? -3.36000  8.48300   39.06200  1.000 9.96000  ? 204 TRP D CA  1 
ATOM   4805 C C   . TRP D 1 203 ? -2.76600  7.84200   37.79300  1.000 10.10000 ? 204 TRP D C   1 
ATOM   4806 O O   . TRP D 1 203 ? -1.90000  6.96100   37.88000  1.000 11.34000 ? 204 TRP D O   1 
ATOM   4807 C CB  . TRP D 1 203 ? -2.37600  9.49400   39.54000  1.000 9.58000  ? 204 TRP D CB  1 
ATOM   4808 C CG  . TRP D 1 203 ? -2.81300  10.34900  40.65600  1.000 13.89000 ? 204 TRP D CG  1 
ATOM   4809 C CD1 . TRP D 1 203 ? -2.74100  10.06400  42.02300  1.000 10.14000 ? 204 TRP D CD1 1 
ATOM   4810 C CD2 . TRP D 1 203 ? -3.29100  11.69000  40.54000  1.000 12.25000 ? 204 TRP D CD2 1 
ATOM   4811 N NE1 . TRP D 1 203 ? -3.19600  11.17000  42.73500  1.000 14.17000 ? 204 TRP D NE1 1 
ATOM   4812 C CE2 . TRP D 1 203 ? -3.52500  12.17100  41.86200  1.000 15.93000 ? 204 TRP D CE2 1 
ATOM   4813 C CE3 . TRP D 1 203 ? -3.55100  12.53400  39.45100  1.000 14.28000 ? 204 TRP D CE3 1 
ATOM   4814 C CZ2 . TRP D 1 203 ? -3.97800  13.45100  42.10800  1.000 16.98000 ? 204 TRP D CZ2 1 
ATOM   4815 C CZ3 . TRP D 1 203 ? -4.03400  13.82500  39.70600  1.000 21.91000 ? 204 TRP D CZ3 1 
ATOM   4816 C CH2 . TRP D 1 203 ? -4.24100  14.25400  41.01600  1.000 16.18000 ? 204 TRP D CH2 1 
ATOM   4817 N N   . ALA D 1 204 ? -3.16100  8.36700   36.63000  1.000 10.16000 ? 205 ALA D N   1 
ATOM   4818 C CA  . ALA D 1 204 ? -2.57100  8.02600   35.33300  1.000 12.36000 ? 205 ALA D CA  1 
ATOM   4819 C C   . ALA D 1 204 ? -2.25000  9.34900   34.65900  1.000 11.07000 ? 205 ALA D C   1 
ATOM   4820 O O   . ALA D 1 204 ? -3.14200  10.19400  34.49400  1.000 11.03000 ? 205 ALA D O   1 
ATOM   4821 C CB  . ALA D 1 204 ? -3.54100  7.18900   34.47800  1.000 10.56000 ? 205 ALA D CB  1 
ATOM   4822 N N   . LEU D 1 205 ? -0.97100  9.58600   34.35600  1.000 11.34000 ? 206 LEU D N   1 
ATOM   4823 C CA  . LEU D 1 205 ? -0.56600  10.89000  33.87000  1.000 8.65000  ? 206 LEU D CA  1 
ATOM   4824 C C   . LEU D 1 205 ? 0.25300   10.75600  32.59700  1.000 10.71000 ? 206 LEU D C   1 
ATOM   4825 O O   . LEU D 1 205 ? 0.93600   9.74400   32.38700  1.000 9.83000  ? 206 LEU D O   1 
ATOM   4826 C CB  . LEU D 1 205 ? 0.28300   11.66000  34.94400  1.000 9.22000  ? 206 LEU D CB  1 
ATOM   4827 C CG  . LEU D 1 205 ? -0.50600  11.95300  36.24900  1.000 14.90000 ? 206 LEU D CG  1 
ATOM   4828 C CD1 . LEU D 1 205 ? 0.59100   12.51800  37.18600  1.000 15.66000 ? 206 LEU D CD1 1 
ATOM   4829 C CD2 . LEU D 1 205 ? -1.67700  13.00600  36.14900  1.000 14.60000 ? 206 LEU D CD2 1 
ATOM   4830 N N   . GLY D 1 206 ? 0.18800   11.80900  31.76800  1.000 11.08000 ? 207 GLY D N   1 
ATOM   4831 C CA  . GLY D 1 206 ? 1.05600   11.88900  30.58400  1.000 10.31000 ? 207 GLY D CA  1 
ATOM   4832 C C   . GLY D 1 206 ? 0.82400   10.81500  29.56000  1.000 10.89000 ? 207 GLY D C   1 
ATOM   4833 O O   . GLY D 1 206 ? 1.75400   10.48700  28.82600  1.000 12.40000 ? 207 GLY D O   1 
ATOM   4834 N N   . PHE D 1 207 ? -0.41200  10.26700  29.43500  1.000 9.27000  ? 208 PHE D N   1 
ATOM   4835 C CA  . PHE D 1 207 ? -0.56600  9.17200   28.48600  1.000 10.48000 ? 208 PHE D CA  1 
ATOM   4836 C C   . PHE D 1 207 ? -1.17400  9.64300   27.14600  1.000 13.33000 ? 208 PHE D C   1 
ATOM   4837 O O   . PHE D 1 207 ? -1.83100  10.69300  27.05500  1.000 10.48000 ? 208 PHE D O   1 
ATOM   4838 C CB  . PHE D 1 207 ? -1.41100  8.02200   29.08300  1.000 8.77000  ? 208 PHE D CB  1 
ATOM   4839 C CG  . PHE D 1 207 ? -2.75100  8.45500   29.62600  1.000 10.67000 ? 208 PHE D CG  1 
ATOM   4840 C CD1 . PHE D 1 207 ? -3.91500  8.40200   28.81800  1.000 10.56000 ? 208 PHE D CD1 1 
ATOM   4841 C CD2 . PHE D 1 207 ? -2.88400  8.81400   30.99400  1.000 9.64000  ? 208 PHE D CD2 1 
ATOM   4842 C CE1 . PHE D 1 207 ? -5.19900  8.76500   29.35200  1.000 10.05000 ? 208 PHE D CE1 1 
ATOM   4843 C CE2 . PHE D 1 207 ? -4.13900  9.14500   31.54700  1.000 11.10000 ? 208 PHE D CE2 1 
ATOM   4844 C CZ  . PHE D 1 207 ? -5.31000  9.11600   30.68200  1.000 11.19000 ? 208 PHE D CZ  1 
ATOM   4845 N N   . TYR D 1 208 ? -0.97800  8.80400   26.11100  1.000 9.45000  ? 209 TYR D N   1 
ATOM   4846 C CA  . TYR D 1 208 ? -1.49900  9.06400   24.77500  1.000 10.31000 ? 209 TYR D CA  1 
ATOM   4847 C C   . TYR D 1 208 ? -1.60500  7.70000   24.09200  1.000 12.62000 ? 209 TYR D C   1 
ATOM   4848 O O   . TYR D 1 208 ? -0.62200  6.93100   24.12100  1.000 14.13000 ? 209 TYR D O   1 
ATOM   4849 C CB  . TYR D 1 208 ? -0.59700  10.01300  23.95600  1.000 9.43000  ? 209 TYR D CB  1 
ATOM   4850 C CG  . TYR D 1 208 ? -1.22300  10.28800  22.57700  1.000 10.10000 ? 209 TYR D CG  1 
ATOM   4851 C CD1 . TYR D 1 208 ? -1.01700  9.40800   21.50300  1.000 10.73000 ? 209 TYR D CD1 1 
ATOM   4852 C CD2 . TYR D 1 208 ? -2.13500  11.32600  22.41900  1.000 10.50000 ? 209 TYR D CD2 1 
ATOM   4853 C CE1 . TYR D 1 208 ? -1.67500  9.62500   20.27500  1.000 12.80000 ? 209 TYR D CE1 1 
ATOM   4854 C CE2 . TYR D 1 208 ? -2.78400  11.56800  21.16700  1.000 11.99000 ? 209 TYR D CE2 1 
ATOM   4855 C CZ  . TYR D 1 208 ? -2.56300  10.70800  20.13600  1.000 14.57000 ? 209 TYR D CZ  1 
ATOM   4856 O OH  . TYR D 1 208 ? -3.16900  10.92600  18.90900  1.000 12.85000 ? 209 TYR D OH  1 
ATOM   4857 N N   . PRO D 1 209 ? -2.71700  7.40000   23.39600  1.000 12.95000 ? 210 PRO D N   1 
ATOM   4858 C CA  . PRO D 1 209 ? -3.97500  8.20300   23.22900  1.000 10.54000 ? 210 PRO D CA  1 
ATOM   4859 C C   . PRO D 1 209 ? -4.81600  8.27200   24.51000  1.000 14.05000 ? 210 PRO D C   1 
ATOM   4860 O O   . PRO D 1 209 ? -4.37700  7.78000   25.56100  1.000 10.30000 ? 210 PRO D O   1 
ATOM   4861 C CB  . PRO D 1 209 ? -4.71400  7.46400   22.08700  1.000 12.66000 ? 210 PRO D CB  1 
ATOM   4862 C CG  . PRO D 1 209 ? -4.22200  6.06100   22.22600  1.000 17.73000 ? 210 PRO D CG  1 
ATOM   4863 C CD  . PRO D 1 209 ? -2.77800  6.15800   22.62200  1.000 16.46000 ? 210 PRO D CD  1 
ATOM   4864 N N   . ALA D 1 210 ? -5.98000  8.96900   24.46700  1.000 10.15000 ? 211 ALA D N   1 
ATOM   4865 C CA  . ALA D 1 210 ? -6.71300  9.26000   25.67600  1.000 12.49000 ? 211 ALA D CA  1 
ATOM   4866 C C   . ALA D 1 210 ? -7.45300  8.05200   26.23700  1.000 14.49000 ? 211 ALA D C   1 
ATOM   4867 O O   . ALA D 1 210 ? -7.78400  8.02700   27.42100  1.000 11.09000 ? 211 ALA D O   1 
ATOM   4868 C CB  . ALA D 1 210 ? -7.73000  10.38800  25.41900  1.000 14.67000 ? 211 ALA D CB  1 
ATOM   4869 N N   . GLU D 1 211 ? -7.79300  7.08000   25.41200  1.000 10.97000 ? 212 GLU D N   1 
ATOM   4870 C CA  . GLU D 1 211 ? -8.52000  5.90800   25.89800  1.000 13.55000 ? 212 GLU D CA  1 
ATOM   4871 C C   . GLU D 1 211 ? -7.73900  5.22900   27.01800  1.000 13.01000 ? 212 GLU D C   1 
ATOM   4872 O O   . GLU D 1 211 ? -6.56000  4.93400   26.83900  1.000 14.48000 ? 212 GLU D O   1 
ATOM   4873 C CB  . GLU D 1 211 ? -8.67900  4.92100   24.73600  1.000 14.73000 ? 212 GLU D CB  1 
ATOM   4874 C CG  . GLU D 1 211 ? -9.23300  3.56400   25.12400  1.000 19.61000 ? 212 GLU D CG  1 
ATOM   4875 C CD  . GLU D 1 211 ? -10.65200 3.62100   25.74600  1.000 32.27000 ? 212 GLU D CD  1 
ATOM   4876 O OE1 . GLU D 1 211 ? -11.44500 4.53100   25.40800  1.000 37.74000 ? 212 GLU D OE1 1 
ATOM   4877 O OE2 . GLU D 1 211 ? -10.99900 2.69700   26.54200  1.000 36.03000 ? 212 GLU D OE2 1 
ATOM   4878 N N   . ILE D 1 212 ? -8.39700  4.90700   28.13100  1.000 11.98000 ? 213 ILE D N   1 
ATOM   4879 C CA  . ILE D 1 212 ? -7.73400  4.27000   29.27700  1.000 12.37000 ? 213 ILE D CA  1 
ATOM   4880 C C   . ILE D 1 212 ? -8.84500  3.72200   30.15200  1.000 15.11000 ? 213 ILE D C   1 
ATOM   4881 O O   . ILE D 1 212 ? -9.96000  4.22100   30.10600  1.000 16.30000 ? 213 ILE D O   1 
ATOM   4882 C CB  . ILE D 1 212 ? -6.87400  5.30000   30.05500  1.000 13.06000 ? 213 ILE D CB  1 
ATOM   4883 C CG1 . ILE D 1 212 ? -5.84200  4.61200   30.96600  1.000 11.36000 ? 213 ILE D CG1 1 
ATOM   4884 C CG2 . ILE D 1 212 ? -7.78700  6.24300   30.85100  1.000 12.30000 ? 213 ILE D CG2 1 
ATOM   4885 C CD1 . ILE D 1 212 ? -4.83300  5.59900   31.67100  1.000 11.65000 ? 213 ILE D CD1 1 
ATOM   4886 N N   . THR D 1 213 ? -8.54400  2.68800   30.93500  1.000 13.46000 ? 214 THR D N   1 
ATOM   4887 C CA  . THR D 1 213 ? -9.43800  2.17300   31.98300  1.000 14.66000 ? 214 THR D CA  1 
ATOM   4888 C C   . THR D 1 213 ? -8.71100  2.12100   33.32000  1.000 15.49000 ? 214 THR D C   1 
ATOM   4889 O O   . THR D 1 213 ? -7.60100  1.57400   33.39900  1.000 14.14000 ? 214 THR D O   1 
ATOM   4890 C CB  . THR D 1 213 ? -9.94100  0.75000   31.66800  1.000 20.91000 ? 214 THR D CB  1 
ATOM   4891 O OG1 . THR D 1 213 ? -10.50300 0.75700   30.34200  1.000 19.87000 ? 214 THR D OG1 1 
ATOM   4892 C CG2 . THR D 1 213 ? -11.02400 0.34500   32.70700  1.000 18.14000 ? 214 THR D CG2 1 
ATOM   4893 N N   . LEU D 1 214 ? -9.31200  2.70800   34.33600  1.000 10.58000 ? 215 LEU D N   1 
ATOM   4894 C CA  . LEU D 1 214 ? -8.74500  2.72100   35.70400  1.000 15.44000 ? 215 LEU D CA  1 
ATOM   4895 C C   . LEU D 1 214 ? -9.81000  2.16300   36.62000  1.000 17.15000 ? 215 LEU D C   1 
ATOM   4896 O O   . LEU D 1 214 ? -10.92700 2.67400   36.61400  1.000 17.79000 ? 215 LEU D O   1 
ATOM   4897 C CB  . LEU D 1 214 ? -8.48800  4.12600   36.19700  1.000 15.49000 ? 215 LEU D CB  1 
ATOM   4898 C CG  . LEU D 1 214 ? -7.33500  4.96400   35.78200  1.000 23.50000 ? 215 LEU D CG  1 
ATOM   4899 C CD1 . LEU D 1 214 ? -7.38700  6.33800   36.50500  1.000 11.86000 ? 215 LEU D CD1 1 
ATOM   4900 C CD2 . LEU D 1 214 ? -6.10300  4.18300   36.09800  1.000 18.55000 ? 215 LEU D CD2 1 
ATOM   4901 N N   . THR D 1 215 ? -9.47500  1.16500   37.43400  1.000 14.35000 ? 216 THR D N   1 
ATOM   4902 C CA  . THR D 1 215 ? -10.49700 0.55800   38.25900  1.000 18.02000 ? 216 THR D CA  1 
ATOM   4903 C C   . THR D 1 215 ? -9.86600  0.22100   39.59900  1.000 16.17000 ? 216 THR D C   1 
ATOM   4904 O O   . THR D 1 215 ? -8.67400  -0.04300  39.67800  1.000 16.64000 ? 216 THR D O   1 
ATOM   4905 C CB  . THR D 1 215 ? -11.05200 -0.73000  37.63900  1.000 17.08000 ? 216 THR D CB  1 
ATOM   4906 O OG1 . THR D 1 215 ? -10.00400 -1.65900  37.60800  1.000 24.60000 ? 216 THR D OG1 1 
ATOM   4907 C CG2 . THR D 1 215 ? -11.52900 -0.56600  36.20900  1.000 16.55000 ? 216 THR D CG2 1 
ATOM   4908 N N   . TRP D 1 216 ? -10.63800 0.32100   40.64900  1.000 15.22000 ? 217 TRP D N   1 
ATOM   4909 C CA  . TRP D 1 216 ? -10.18000 -0.12700  41.96400  1.000 17.13000 ? 217 TRP D CA  1 
ATOM   4910 C C   . TRP D 1 216 ? -10.82900 -1.46400  42.27100  1.000 22.08000 ? 217 TRP D C   1 
ATOM   4911 O O   . TRP D 1 216 ? -12.00900 -1.64800  41.97400  1.000 20.45000 ? 217 TRP D O   1 
ATOM   4912 C CB  . TRP D 1 216 ? -10.56900 0.85400   43.06600  1.000 12.38000 ? 217 TRP D CB  1 
ATOM   4913 C CG  . TRP D 1 216 ? -9.56500  1.99100   43.21800  1.000 12.47000 ? 217 TRP D CG  1 
ATOM   4914 C CD1 . TRP D 1 216 ? -9.73100  3.30300   42.83800  1.000 13.99000 ? 217 TRP D CD1 1 
ATOM   4915 C CD2 . TRP D 1 216 ? -8.32000  1.93000   43.94000  1.000 12.96000 ? 217 TRP D CD2 1 
ATOM   4916 N NE1 . TRP D 1 216 ? -8.58100  4.05200   43.22000  1.000 13.64000 ? 217 TRP D NE1 1 
ATOM   4917 C CE2 . TRP D 1 216 ? -7.71900  3.21100   43.87600  1.000 11.34000 ? 217 TRP D CE2 1 
ATOM   4918 C CE3 . TRP D 1 216 ? -7.62000  0.88400   44.57200  1.000 14.07000 ? 217 TRP D CE3 1 
ATOM   4919 C CZ2 . TRP D 1 216 ? -6.46900  3.47500   44.43100  1.000 11.23000 ? 217 TRP D CZ2 1 
ATOM   4920 C CZ3 . TRP D 1 216 ? -6.34500  1.13300   45.09900  1.000 11.64000 ? 217 TRP D CZ3 1 
ATOM   4921 C CH2 . TRP D 1 216 ? -5.79900  2.42900   45.03400  1.000 13.54000 ? 217 TRP D CH2 1 
ATOM   4922 N N   . GLN D 1 217 ? -10.07000 -2.37000  42.88900  1.000 17.63000 ? 218 GLN D N   1 
ATOM   4923 C CA  . GLN D 1 217 ? -10.59600 -3.62900  43.40400  1.000 20.03000 ? 218 GLN D CA  1 
ATOM   4924 C C   . GLN D 1 217 ? -10.34400 -3.71400  44.89300  1.000 21.41000 ? 218 GLN D C   1 
ATOM   4925 O O   . GLN D 1 217 ? -9.35000  -3.18500  45.38200  1.000 16.48000 ? 218 GLN D O   1 
ATOM   4926 C CB  . GLN D 1 217 ? -9.91800  -4.82300  42.76600  1.000 20.22000 ? 218 GLN D CB  1 
ATOM   4927 C CG  . GLN D 1 217 ? -10.39000 -5.01100  41.34400  1.000 22.50000 ? 218 GLN D CG  1 
ATOM   4928 C CD  . GLN D 1 217 ? -9.74300  -6.18000  40.66600  1.000 30.35000 ? 218 GLN D CD  1 
ATOM   4929 O OE1 . GLN D 1 217 ? -9.18800  -7.06500  41.32600  1.000 30.43000 ? 218 GLN D OE1 1 
ATOM   4930 N NE2 . GLN D 1 217 ? -9.84600  -6.22000  39.33500  1.000 29.16000 ? 218 GLN D NE2 1 
ATOM   4931 N N   . ARG D 1 218 ? -11.23600 -4.42000  45.60600  1.000 19.58000 ? 219 ARG D N   1 
ATOM   4932 C CA  . ARG D 1 218 ? -11.05400 -4.71700  47.03000  1.000 19.31000 ? 219 ARG D CA  1 
ATOM   4933 C C   . ARG D 1 218 ? -11.01700 -6.23100  47.13900  1.000 24.46000 ? 219 ARG D C   1 
ATOM   4934 O O   . ARG D 1 218 ? -12.01000 -6.88900  46.81100  1.000 27.16000 ? 219 ARG D O   1 
ATOM   4935 C CB  . ARG D 1 218 ? -12.22000 -4.14800  47.85300  1.000 23.99000 ? 219 ARG D CB  1 
ATOM   4936 C CG  . ARG D 1 218 ? -12.10200 -4.46900  49.41100  1.000 25.04000 ? 219 ARG D CG  1 
ATOM   4937 C CD  . ARG D 1 218 ? -13.41100 -4.20700  50.16500  1.000 31.41000 ? 219 ARG D CD  1 
ATOM   4938 N NE  . ARG D 1 218 ? -13.30800 -4.72600  51.53400  1.000 41.64000 ? 219 ARG D NE  1 
ATOM   4939 C CZ  . ARG D 1 218 ? -12.91000 -4.06500  52.62200  1.000 38.49000 ? 219 ARG D CZ  1 
ATOM   4940 N NH1 . ARG D 1 218 ? -12.77200 -2.75300  52.64100  1.000 31.91000 ? 219 ARG D NH1 1 
ATOM   4941 N NH2 . ARG D 1 218 ? -12.69000 -4.74300  53.74400  1.000 51.43000 ? 219 ARG D NH2 1 
ATOM   4942 N N   . ASP D 1 219 ? -9.88800  -6.80100  47.55600  1.000 20.19000 ? 220 ASP D N   1 
ATOM   4943 C CA  . ASP D 1 219 ? -9.78700  -8.26500  47.58700  1.000 27.57000 ? 220 ASP D CA  1 
ATOM   4944 C C   . ASP D 1 219 ? -10.14800 -8.87000  46.22800  1.000 31.38000 ? 220 ASP D C   1 
ATOM   4945 O O   . ASP D 1 219 ? -10.75200 -9.93300  46.14500  1.000 24.93000 ? 220 ASP D O   1 
ATOM   4946 C CB  . ASP D 1 219 ? -10.69900 -8.87900  48.67400  1.000 25.98000 ? 220 ASP D CB  1 
ATOM   4947 C CG  . ASP D 1 219 ? -10.25500 -8.53200  50.08800  1.000 29.37000 ? 220 ASP D CG  1 
ATOM   4948 O OD1 . ASP D 1 219 ? -9.02900  -8.42000  50.36400  1.000 25.90000 ? 220 ASP D OD1 1 
ATOM   4949 O OD2 . ASP D 1 219 ? -11.13700 -8.42800  50.93800  1.000 37.56000 ? 220 ASP D OD2 1 
ATOM   4950 N N   . GLY D 1 220 ? -9.80700  -8.18800  45.14300  1.000 29.35000 ? 221 GLY D N   1 
ATOM   4951 C CA  . GLY D 1 220 ? -10.07000 -8.68900  43.80500  1.000 28.42000 ? 221 GLY D CA  1 
ATOM   4952 C C   . GLY D 1 220 ? -11.47700 -8.47100  43.28700  1.000 25.57000 ? 221 GLY D C   1 
ATOM   4953 O O   . GLY D 1 220 ? -11.80000 -8.95400  42.19800  1.000 29.93000 ? 221 GLY D O   1 
ATOM   4954 N N   . GLU D 1 221 ? -12.32400 -7.76100  44.01800  1.000 25.66000 ? 222 GLU D N   1 
ATOM   4955 C CA  . GLU D 1 221 ? -13.71000 -7.52800  43.63600  1.000 32.08000 ? 222 GLU D CA  1 
ATOM   4956 C C   . GLU D 1 221 ? -13.87500 -6.07900  43.19100  1.000 33.91000 ? 222 GLU D C   1 
ATOM   4957 O O   . GLU D 1 221 ? -13.49900 -5.15000  43.92700  1.000 27.20000 ? 222 GLU D O   1 
ATOM   4958 C CB  . GLU D 1 221 ? -14.63800 -7.84400  44.81000  1.000 31.47000 ? 222 GLU D CB  1 
ATOM   4959 C CG  . GLU D 1 221 ? -15.04200 -9.34400  44.91400  1.000 48.95000 ? 222 GLU D CG  1 
ATOM   4960 C CD  . GLU D 1 221 ? -15.32000 -9.81100  46.36000  1.000 61.84000 ? 222 GLU D CD  1 
ATOM   4961 O OE1 . GLU D 1 221 ? -16.28100 -9.30400  46.98700  1.000 67.81000 ? 222 GLU D OE1 1 
ATOM   4962 O OE2 . GLU D 1 221 ? -14.60100 -10.71200 46.86800  1.000 55.72000 ? 222 GLU D OE2 1 
ATOM   4963 N N   . ASP D 1 222 ? -14.40300 -5.88500  41.97700  1.000 33.95000 ? 223 ASP D N   1 
ATOM   4964 C CA  . ASP D 1 222 ? -14.52300 -4.53900  41.42900  1.000 33.78000 ? 223 ASP D CA  1 
ATOM   4965 C C   . ASP D 1 222 ? -15.31800 -3.68300  42.39500  1.000 31.02000 ? 223 ASP D C   1 
ATOM   4966 O O   . ASP D 1 222 ? -16.27400 -4.15000  43.00300  1.000 30.50000 ? 223 ASP D O   1 
ATOM   4967 C CB  . ASP D 1 222 ? -15.23100 -4.54300  40.06700  1.000 46.15000 ? 223 ASP D CB  1 
ATOM   4968 C CG  . ASP D 1 222 ? -14.38800 -5.14000  38.95100  1.000 48.40000 ? 223 ASP D CG  1 
ATOM   4969 O OD1 . ASP D 1 222 ? -13.13200 -5.11300  39.00600  1.000 49.15000 ? 223 ASP D OD1 1 
ATOM   4970 O OD2 . ASP D 1 222 ? -14.99500 -5.63500  37.98400  1.000 67.54000 ? 223 ASP D OD2 1 
ATOM   4971 N N   . GLN D 1 223 ? -14.89800 -2.43300  42.54900  1.000 23.87000 ? 224 GLN D N   1 
ATOM   4972 C CA  . GLN D 1 223 ? -15.50500 -1.47400  43.47100  1.000 30.85000 ? 224 GLN D CA  1 
ATOM   4973 C C   . GLN D 1 223 ? -16.26800 -0.39800  42.71600  1.000 29.43000 ? 224 GLN D C   1 
ATOM   4974 O O   . GLN D 1 223 ? -16.22900 0.78200   43.07100  1.000 24.92000 ? 224 GLN D O   1 
ATOM   4975 C CB  . GLN D 1 223 ? -14.43000 -0.83000  44.34100  1.000 26.51000 ? 224 GLN D CB  1 
ATOM   4976 C CG  . GLN D 1 223 ? -13.82300 -1.78600  45.30300  1.000 23.92000 ? 224 GLN D CG  1 
ATOM   4977 C CD  . GLN D 1 223 ? -14.78700 -2.05600  46.38900  1.000 34.28000 ? 224 GLN D CD  1 
ATOM   4978 O OE1 . GLN D 1 223 ? -15.01900 -1.19800  47.24900  1.000 44.42000 ? 224 GLN D OE1 1 
ATOM   4979 N NE2 . GLN D 1 223 ? -15.37300 -3.23800  46.37100  1.000 31.61000 ? 224 GLN D NE2 1 
ATOM   4980 N N   . THR D 1 224 ? -16.94600 -0.78600  41.63800  1.000 36.35000 ? 225 THR D N   1 
ATOM   4981 C CA  . THR D 1 224 ? -17.41000 0.22200   40.68400  1.000 36.18000 ? 225 THR D CA  1 
ATOM   4982 C C   . THR D 1 224 ? -18.35100 1.24800   41.32900  1.000 35.33000 ? 225 THR D C   1 
ATOM   4983 O O   . THR D 1 224 ? -18.19200 2.46800   41.10700  1.000 33.22000 ? 225 THR D O   1 
ATOM   4984 C CB  . THR D 1 224 ? -18.06400 -0.45600  39.48800  1.000 41.42000 ? 225 THR D CB  1 
ATOM   4985 O OG1 . THR D 1 224 ? -18.79400 0.53800   38.76400  1.000 51.81000 ? 225 THR D OG1 1 
ATOM   4986 C CG2 . THR D 1 224 ? -19.00400 -1.57400  39.93300  1.000 42.82000 ? 225 THR D CG2 1 
ATOM   4987 N N   . GLN D 1 225 ? -19.30100 0.79800   42.17500  1.000 27.25000 ? 226 GLN D N   1 
ATOM   4988 C CA  . GLN D 1 225 ? -20.23400 1.76800   42.75800  1.000 34.40000 ? 226 GLN D CA  1 
ATOM   4989 C C   . GLN D 1 225 ? -19.57500 2.68600   43.78000  1.000 37.18000 ? 226 GLN D C   1 
ATOM   4990 O O   . GLN D 1 225 ? -20.12600 3.74600   44.08900  1.000 40.87000 ? 226 GLN D O   1 
ATOM   4991 C CB  . GLN D 1 225 ? -21.42600 1.08500   43.44700  1.000 40.73000 ? 226 GLN D CB  1 
ATOM   4992 C CG  . GLN D 1 225 ? -22.58100 0.73600   42.51600  1.000 42.76000 ? 226 GLN D CG  1 
ATOM   4993 C CD  . GLN D 1 225 ? -23.00200 1.90000   41.63800  0.000 39.20000 ? 226 GLN D CD  1 
ATOM   4994 O OE1 . GLN D 1 225 ? -23.09100 1.76600   40.41800  0.000 39.12000 ? 226 GLN D OE1 1 
ATOM   4995 N NE2 . GLN D 1 225 ? -23.27700 3.04400   42.25600  0.000 38.72000 ? 226 GLN D NE2 1 
ATOM   4996 N N   . ASP D 1 226 ? -18.44900 2.28500   44.36100  1.000 29.24000 ? 227 ASP D N   1 
ATOM   4997 C CA  . ASP D 1 226 ? -17.76700 3.10600   45.35500  1.000 30.89000 ? 227 ASP D CA  1 
ATOM   4998 C C   . ASP D 1 226 ? -16.59100 3.92200   44.80100  1.000 24.76000 ? 227 ASP D C   1 
ATOM   4999 O O   . ASP D 1 226 ? -15.98000 4.67500   45.55400  1.000 24.85000 ? 227 ASP D O   1 
ATOM   5000 C CB  . ASP D 1 226 ? -17.31700 2.22300   46.53100  1.000 27.45000 ? 227 ASP D CB  1 
ATOM   5001 C CG  . ASP D 1 226 ? -18.52000 1.63300   47.30900  1.000 44.61000 ? 227 ASP D CG  1 
ATOM   5002 O OD1 . ASP D 1 226 ? -19.12100 0.60600   46.91400  1.000 46.71000 ? 227 ASP D OD1 1 
ATOM   5003 O OD2 . ASP D 1 226 ? -18.91900 2.29100   48.28700  1.000 49.99000 ? 227 ASP D OD2 1 
ATOM   5004 N N   . THR D 1 227 ? -16.31700 3.88300   43.50700  1.000 24.63000 ? 228 THR D N   1 
ATOM   5005 C CA  . THR D 1 227 ? -15.14600 4.57700   42.97200  1.000 22.44000 ? 228 THR D CA  1 
ATOM   5006 C C   . THR D 1 227 ? -15.57700 5.90900   42.38500  1.000 28.30000 ? 228 THR D C   1 
ATOM   5007 O O   . THR D 1 227 ? -16.51400 5.93900   41.57200  1.000 24.22000 ? 228 THR D O   1 
ATOM   5008 C CB  . THR D 1 227 ? -14.51900 3.74100   41.87600  1.000 26.12000 ? 228 THR D CB  1 
ATOM   5009 O OG1 . THR D 1 227 ? -14.13200 2.45800   42.39400  1.000 26.05000 ? 228 THR D OG1 1 
ATOM   5010 C CG2 . THR D 1 227 ? -13.32100 4.49300   41.17200  1.000 18.41000 ? 228 THR D CG2 1 
ATOM   5011 N N   . GLU D 1 228 ? -14.87700 6.99800   42.74400  1.000 18.21000 ? 229 GLU D N   1 
ATOM   5012 C CA  . GLU D 1 228 ? -15.08600 8.27500   42.07200  1.000 19.15000 ? 229 GLU D CA  1 
ATOM   5013 C C   . GLU D 1 228 ? -14.11600 8.30100   40.90100  1.000 20.71000 ? 229 GLU D C   1 
ATOM   5014 O O   . GLU D 1 228 ? -12.92000 8.09100   41.09800  1.000 13.92000 ? 229 GLU D O   1 
ATOM   5015 C CB  . GLU D 1 228 ? -14.88600 9.49200   42.98200  1.000 23.33000 ? 229 GLU D CB  1 
ATOM   5016 C CG  . GLU D 1 228 ? -15.01700 10.78900  42.14400  1.000 21.97000 ? 229 GLU D CG  1 
ATOM   5017 C CD  . GLU D 1 228 ? -14.92900 12.05700  42.94400  1.000 32.87000 ? 229 GLU D CD  1 
ATOM   5018 O OE1 . GLU D 1 228 ? -14.39300 11.95700  44.06200  1.000 26.49000 ? 229 GLU D OE1 1 
ATOM   5019 O OE2 . GLU D 1 228 ? -15.26800 13.16500  42.39900  1.000 32.35000 ? 229 GLU D OE2 1 
ATOM   5020 N N   . LEU D 1 229 ? -14.63400 8.42900   39.68300  1.000 14.92000 ? 230 LEU D N   1 
ATOM   5021 C CA  . LEU D 1 229 ? -13.79100 8.43100   38.47600  1.000 14.73000 ? 230 LEU D CA  1 
ATOM   5022 C C   . LEU D 1 229 ? -13.95200 9.78000   37.78700  1.000 20.79000 ? 230 LEU D C   1 
ATOM   5023 O O   . LEU D 1 229 ? -15.08600 10.18800  37.48200  1.000 24.77000 ? 230 LEU D O   1 
ATOM   5024 C CB  . LEU D 1 229 ? -14.24100 7.27400   37.58000  1.000 20.43000 ? 230 LEU D CB  1 
ATOM   5025 C CG  . LEU D 1 229 ? -13.43300 6.76200   36.42400  1.000 27.71000 ? 230 LEU D CG  1 
ATOM   5026 C CD1 . LEU D 1 229 ? -12.18300 6.11100   36.98500  1.000 19.20000 ? 230 LEU D CD1 1 
ATOM   5027 C CD2 . LEU D 1 229 ? -14.30500 5.78900   35.57600  1.000 23.12000 ? 230 LEU D CD2 1 
ATOM   5028 N N   . VAL D 1 230 ? -12.83700 10.51900  37.56600  1.000 11.82000 ? 231 VAL D N   1 
ATOM   5029 C CA  . VAL D 1 230 ? -13.04300 11.79200  36.88400  1.000 10.72000 ? 231 VAL D CA  1 
ATOM   5030 C C   . VAL D 1 230 ? -12.92600 11.57800  35.38600  1.000 13.90000 ? 231 VAL D C   1 
ATOM   5031 O O   . VAL D 1 230 ? -12.33000 10.60500  34.90500  1.000 13.37000 ? 231 VAL D O   1 
ATOM   5032 C CB  . VAL D 1 230 ? -12.11000 12.91200  37.35000  1.000 12.61000 ? 231 VAL D CB  1 
ATOM   5033 C CG1 . VAL D 1 230 ? -12.38200 13.22500  38.78500  1.000 14.76000 ? 231 VAL D CG1 1 
ATOM   5034 C CG2 . VAL D 1 230 ? -10.59800 12.55000  37.07000  1.000 14.12000 ? 231 VAL D CG2 1 
ATOM   5035 N N   . GLU D 1 231 ? -13.53700 12.49000  34.63200  1.000 13.63000 ? 232 GLU D N   1 
ATOM   5036 C CA  . GLU D 1 231 ? -13.40900 12.44900  33.18100  1.000 11.52000 ? 232 GLU D CA  1 
ATOM   5037 C C   . GLU D 1 231 ? -11.95000 12.59000  32.76300  1.000 12.00000 ? 232 GLU D C   1 
ATOM   5038 O O   . GLU D 1 231 ? -11.19900 13.39400  33.32800  1.000 11.08000 ? 232 GLU D O   1 
ATOM   5039 C CB  . GLU D 1 231 ? -14.24500 13.59500  32.56200  1.000 11.23000 ? 232 GLU D CB  1 
ATOM   5040 C CG  . GLU D 1 231 ? -14.44900 13.52200  31.09800  1.000 22.08000 ? 232 GLU D CG  1 
ATOM   5041 C CD  . GLU D 1 231 ? -15.02200 14.87300  30.50600  1.000 36.85000 ? 232 GLU D CD  1 
ATOM   5042 O OE1 . GLU D 1 231 ? -15.51900 15.68100  31.32600  1.000 32.78000 ? 232 GLU D OE1 1 
ATOM   5043 O OE2 . GLU D 1 231 ? -14.99500 15.05400  29.22300  1.000 42.22000 ? 232 GLU D OE2 1 
ATOM   5044 N N   . THR D 1 232 ? -11.54200 11.80100  31.76400  1.000 10.64000 ? 233 THR D N   1 
ATOM   5045 C CA  . THR D 1 232 ? -10.19100 11.94500  31.22000  1.000 11.61000 ? 233 THR D CA  1 
ATOM   5046 C C   . THR D 1 232 ? -10.01000 13.38600  30.74600  1.000 12.58000 ? 233 THR D C   1 
ATOM   5047 O O   . THR D 1 232 ? -10.91600 13.94900  30.14000  1.000 13.33000 ? 233 THR D O   1 
ATOM   5048 C CB  . THR D 1 232 ? -10.01900 10.94400  30.06100  1.000 13.05000 ? 233 THR D CB  1 
ATOM   5049 O OG1 . THR D 1 232 ? -10.15400 9.61800   30.60000  1.000 15.06000 ? 233 THR D OG1 1 
ATOM   5050 C CG2 . THR D 1 232 ? -8.61400  11.05200  29.42800  1.000 8.81000  ? 233 THR D CG2 1 
ATOM   5051 N N   . ARG D 1 233 ? -8.89600  14.01900  31.09500  1.000 11.39000 ? 234 ARG D N   1 
ATOM   5052 C CA  . ARG D 1 233 ? -8.74900  15.45300  30.84800  1.000 8.90000  ? 234 ARG D CA  1 
ATOM   5053 C C   . ARG D 1 233 ? -7.41400  15.73400  30.18300  1.000 11.27000 ? 234 ARG D C   1 
ATOM   5054 O O   . ARG D 1 233 ? -6.45300  14.99300  30.39900  1.000 10.46000 ? 234 ARG D O   1 
ATOM   5055 C CB  . ARG D 1 233 ? -8.81500  16.22600  32.18900  1.000 9.92000  ? 234 ARG D CB  1 
ATOM   5056 C CG  . ARG D 1 233 ? -7.63700  15.79900  33.16200  1.000 10.16000 ? 234 ARG D CG  1 
ATOM   5057 C CD  . ARG D 1 233 ? -8.01100  16.17600  34.63900  1.000 11.49000 ? 234 ARG D CD  1 
ATOM   5058 N NE  . ARG D 1 233 ? -6.83900  16.10000  35.50000  1.000 11.19000 ? 234 ARG D NE  1 
ATOM   5059 C CZ  . ARG D 1 233 ? -6.87200  16.23500  36.81800  1.000 12.94000 ? 234 ARG D CZ  1 
ATOM   5060 N NH1 . ARG D 1 233 ? -8.00600  16.45400  37.46700  1.000 11.08000 ? 234 ARG D NH1 1 
ATOM   5061 N NH2 . ARG D 1 233 ? -5.72800  16.18100  37.49700  1.000 11.89000 ? 234 ARG D NH2 1 
ATOM   5062 N N   . PRO D 1 234 ? -7.32800  16.79100  29.37100  1.000 12.36000 ? 235 PRO D N   1 
ATOM   5063 C CA  . PRO D 1 234 ? -6.08900  17.10000  28.66500  1.000 11.74000 ? 235 PRO D CA  1 
ATOM   5064 C C   . PRO D 1 234 ? -5.06000  17.73200  29.58500  1.000 10.78000 ? 235 PRO D C   1 
ATOM   5065 O O   . PRO D 1 234 ? -5.39200  18.61700  30.37700  1.000 12.88000 ? 235 PRO D O   1 
ATOM   5066 C CB  . PRO D 1 234 ? -6.53200  18.11900  27.60600  1.000 12.72000 ? 235 PRO D CB  1 
ATOM   5067 C CG  . PRO D 1 234 ? -7.72500  18.83800  28.23800  1.000 11.09000 ? 235 PRO D CG  1 
ATOM   5068 C CD  . PRO D 1 234 ? -8.44600  17.68700  28.96900  1.000 12.76000 ? 235 PRO D CD  1 
ATOM   5069 N N   . ALA D 1 235 ? -3.80900  17.26700  29.47500  1.000 10.10000 ? 236 ALA D N   1 
ATOM   5070 C CA  . ALA D 1 235 ? -2.75800  17.93300  30.27300  1.000 11.29000 ? 236 ALA D CA  1 
ATOM   5071 C C   . ALA D 1 235 ? -2.40500  19.29200  29.70300  1.000 14.13000 ? 236 ALA D C   1 
ATOM   5072 O O   . ALA D 1 235 ? -1.91400  20.16400  30.45200  1.000 14.22000 ? 236 ALA D O   1 
ATOM   5073 C CB  . ALA D 1 235 ? -1.44700  17.09300  30.34900  1.000 11.39000 ? 236 ALA D CB  1 
ATOM   5074 N N   . GLY D 1 236 ? -2.64100  19.48800  28.39100  1.000 14.41000 ? 237 GLY D N   1 
ATOM   5075 C CA  . GLY D 1 236 ? -2.30900  20.71300  27.69700  1.000 15.23000 ? 237 GLY D CA  1 
ATOM   5076 C C   . GLY D 1 236 ? -1.07800  20.60100  26.83100  1.000 15.54000 ? 237 GLY D C   1 
ATOM   5077 O O   . GLY D 1 236 ? -0.79100  21.51000  26.03300  1.000 17.29000 ? 237 GLY D O   1 
ATOM   5078 N N   . ASP D 1 237 ? -0.34300  19.50500  26.95100  1.000 13.31000 ? 238 ASP D N   1 
ATOM   5079 C CA  . ASP D 1 237 ? 0.83300   19.26300  26.12500  1.000 12.92000 ? 238 ASP D CA  1 
ATOM   5080 C C   . ASP D 1 237 ? 0.62900   18.14700  25.10700  1.000 14.77000 ? 238 ASP D C   1 
ATOM   5081 O O   . ASP D 1 237 ? 1.61500   17.61600  24.59000  1.000 15.66000 ? 238 ASP D O   1 
ATOM   5082 C CB  . ASP D 1 237 ? 2.00900   18.92500  27.03400  1.000 17.85000 ? 238 ASP D CB  1 
ATOM   5083 C CG  . ASP D 1 237 ? 1.72500   17.72300  27.91800  1.000 16.54000 ? 238 ASP D CG  1 
ATOM   5084 O OD1 . ASP D 1 237 ? 0.69100   16.98900  27.72200  1.000 13.93000 ? 238 ASP D OD1 1 
ATOM   5085 O OD2 . ASP D 1 237 ? 2.58900   17.47600  28.80000  1.000 17.54000 ? 238 ASP D OD2 1 
ATOM   5086 N N   . GLY D 1 238 ? -0.61700  17.79200  24.80500  1.000 14.73000 ? 239 GLY D N   1 
ATOM   5087 C CA  . GLY D 1 238 ? -0.90300  16.66600  23.92300  1.000 14.22000 ? 239 GLY D CA  1 
ATOM   5088 C C   . GLY D 1 238 ? -1.16600  15.34700  24.62500  1.000 15.97000 ? 239 GLY D C   1 
ATOM   5089 O O   . GLY D 1 238 ? -1.56100  14.37300  23.95400  1.000 13.25000 ? 239 GLY D O   1 
ATOM   5090 N N   . THR D 1 239 ? -0.92000  15.25900  25.94600  1.000 10.32000 ? 240 THR D N   1 
ATOM   5091 C CA  . THR D 1 239 ? -1.17000  13.99200  26.65200  1.000 12.09000 ? 240 THR D CA  1 
ATOM   5092 C C   . THR D 1 239 ? -2.32600  14.20900  27.58600  1.000 9.86000  ? 240 THR D C   1 
ATOM   5093 O O   . THR D 1 239 ? -2.83500  15.32000  27.67800  1.000 11.45000 ? 240 THR D O   1 
ATOM   5094 C CB  . THR D 1 239 ? 0.04000   13.49600  27.44600  1.000 12.87000 ? 240 THR D CB  1 
ATOM   5095 O OG1 . THR D 1 239 ? 0.31200   14.40500  28.50800  1.000 11.71000 ? 240 THR D OG1 1 
ATOM   5096 C CG2 . THR D 1 239 ? 1.31400   13.39900  26.55100  1.000 15.18000 ? 240 THR D CG2 1 
ATOM   5097 N N   . PHE D 1 240 ? -2.77700  13.12000  28.21600  1.000 9.58000  ? 241 PHE D N   1 
ATOM   5098 C CA  . PHE D 1 240 ? -3.98900  13.12100  29.02900  1.000 11.22000 ? 241 PHE D CA  1 
ATOM   5099 C C   . PHE D 1 240 ? -3.71100  12.65300  30.45100  1.000 12.00000 ? 241 PHE D C   1 
ATOM   5100 O O   . PHE D 1 240 ? -2.68000  12.04100  30.73700  1.000 10.94000 ? 241 PHE D O   1 
ATOM   5101 C CB  . PHE D 1 240 ? -5.03200  12.23800  28.34700  1.000 8.37000  ? 241 PHE D CB  1 
ATOM   5102 C CG  . PHE D 1 240 ? -5.42700  12.80400  27.02200  1.000 10.68000 ? 241 PHE D CG  1 
ATOM   5103 C CD1 . PHE D 1 240 ? -4.72100  12.47900  25.87300  1.000 9.47000  ? 241 PHE D CD1 1 
ATOM   5104 C CD2 . PHE D 1 240 ? -6.51700  13.72400  26.95000  1.000 13.85000 ? 241 PHE D CD2 1 
ATOM   5105 C CE1 . PHE D 1 240 ? -5.02800  13.08800  24.63800  1.000 10.98000 ? 241 PHE D CE1 1 
ATOM   5106 C CE2 . PHE D 1 240 ? -6.86400  14.32000  25.72300  1.000 15.35000 ? 241 PHE D CE2 1 
ATOM   5107 C CZ  . PHE D 1 240 ? -6.10300  14.00800  24.55700  1.000 13.35000 ? 241 PHE D CZ  1 
ATOM   5108 N N   . GLN D 1 241 ? -4.71900  12.86300  31.31300  1.000 10.94000 ? 242 GLN D N   1 
ATOM   5109 C CA  . GLN D 1 241 ? -4.66200  12.53200  32.73500  1.000 8.35000  ? 242 GLN D CA  1 
ATOM   5110 C C   . GLN D 1 241 ? -5.98600  11.94300  33.15000  1.000 13.26000 ? 242 GLN D C   1 
ATOM   5111 O O   . GLN D 1 241 ? -7.03000  12.29000  32.59200  1.000 10.50000 ? 242 GLN D O   1 
ATOM   5112 C CB  . GLN D 1 241 ? -4.44000  13.78600  33.60600  1.000 9.96000  ? 242 GLN D CB  1 
ATOM   5113 C CG  . GLN D 1 241 ? -3.23300  14.66600  33.20200  1.000 10.34000 ? 242 GLN D CG  1 
ATOM   5114 C CD  . GLN D 1 241 ? -3.14900  15.90600  34.05900  1.000 14.12000 ? 242 GLN D CD  1 
ATOM   5115 O OE1 . GLN D 1 241 ? -4.08000  16.21900  34.84500  1.000 14.46000 ? 242 GLN D OE1 1 
ATOM   5116 N NE2 . GLN D 1 241 ? -2.02100  16.59900  33.95500  1.000 15.16000 ? 242 GLN D NE2 1 
ATOM   5117 N N   . LYS D 1 242 ? -5.95700  11.13200  34.20300  1.000 7.95000  ? 243 LYS D N   1 
ATOM   5118 C CA  . LYS D 1 242 ? -7.20300  10.60800  34.75200  1.000 10.29000 ? 243 LYS D CA  1 
ATOM   5119 C C   . LYS D 1 242 ? -6.89700  10.13200  36.15200  1.000 12.11000 ? 243 LYS D C   1 
ATOM   5120 O O   . LYS D 1 242 ? -5.75800  9.78800   36.44600  1.000 13.11000 ? 243 LYS D O   1 
ATOM   5121 C CB  . LYS D 1 242 ? -7.75200  9.45100   33.91000  1.000 8.75000  ? 243 LYS D CB  1 
ATOM   5122 C CG  . LYS D 1 242 ? -9.23700  9.11400   34.24600  1.000 10.08000 ? 243 LYS D CG  1 
ATOM   5123 C CD  . LYS D 1 242 ? -9.71800  7.80600   33.55100  1.000 11.63000 ? 243 LYS D CD  1 
ATOM   5124 C CE  . LYS D 1 242 ? -11.31400 7.70200   33.61600  1.000 13.99000 ? 243 LYS D CE  1 
ATOM   5125 N NZ  . LYS D 1 242 ? -12.03000 8.80200   32.89700  1.000 14.22000 ? 243 LYS D NZ  1 
ATOM   5126 N N   . TRP D 1 243 ? -7.89800  10.16600  37.03800  1.000 10.89000 ? 244 TRP D N   1 
ATOM   5127 C CA  . TRP D 1 243 ? -7.70000  9.47200   38.29900  1.000 10.33000 ? 244 TRP D CA  1 
ATOM   5128 C C   . TRP D 1 243 ? -8.99900  8.81800   38.77600  1.000 9.95000  ? 244 TRP D C   1 
ATOM   5129 O O   . TRP D 1 243 ? -10.09800 9.16800   38.34700  1.000 11.23000 ? 244 TRP D O   1 
ATOM   5130 C CB  . TRP D 1 243 ? -7.16800  10.37500  39.42200  1.000 12.33000 ? 244 TRP D CB  1 
ATOM   5131 C CG  . TRP D 1 243 ? -7.92300  11.63600  39.85600  1.000 11.33000 ? 244 TRP D CG  1 
ATOM   5132 C CD1 . TRP D 1 243 ? -7.52100  12.93900  39.59900  1.000 16.86000 ? 244 TRP D CD1 1 
ATOM   5133 C CD2 . TRP D 1 243 ? -9.09700  11.73700  40.68900  1.000 14.78000 ? 244 TRP D CD2 1 
ATOM   5134 N NE1 . TRP D 1 243 ? -8.41200  13.83400  40.18500  1.000 15.05000 ? 244 TRP D NE1 1 
ATOM   5135 C CE2 . TRP D 1 243 ? -9.35500  13.13300  40.88600  1.000 13.83000 ? 244 TRP D CE2 1 
ATOM   5136 C CE3 . TRP D 1 243 ? -9.96100  10.78000  41.30100  1.000 10.52000 ? 244 TRP D CE3 1 
ATOM   5137 C CZ2 . TRP D 1 243 ? -10.40500 13.60400  41.68200  1.000 12.46000 ? 244 TRP D CZ2 1 
ATOM   5138 C CZ3 . TRP D 1 243 ? -11.07100 11.26700  42.04900  1.000 14.35000 ? 244 TRP D CZ3 1 
ATOM   5139 C CH2 . TRP D 1 243 ? -11.27000 12.66600  42.22500  1.000 16.12000 ? 244 TRP D CH2 1 
ATOM   5140 N N   . ALA D 1 244 ? -8.82800  7.88800   39.70400  1.000 11.20000 ? 245 ALA D N   1 
ATOM   5141 C CA  . ALA D 1 244 ? -9.94000  7.10900   40.27800  1.000 13.52000 ? 245 ALA D CA  1 
ATOM   5142 C C   . ALA D 1 244 ? -9.68200  7.01100   41.76400  1.000 13.31000 ? 245 ALA D C   1 
ATOM   5143 O O   . ALA D 1 244 ? -8.56200  6.71900   42.17500  1.000 14.15000 ? 245 ALA D O   1 
ATOM   5144 C CB  . ALA D 1 244 ? -9.99800  5.68600   39.68100  1.000 13.04000 ? 245 ALA D CB  1 
ATOM   5145 N N   . ALA D 1 245 ? -10.69300 7.21300   42.57300  1.000 13.65000 ? 246 ALA D N   1 
ATOM   5146 C CA  . ALA D 1 245 ? -10.48300 7.26400   44.01400  1.000 16.83000 ? 246 ALA D CA  1 
ATOM   5147 C C   . ALA D 1 245 ? -11.56400 6.46000   44.73100  1.000 17.71000 ? 246 ALA D C   1 
ATOM   5148 O O   . ALA D 1 245 ? -12.69700 6.35400   44.23800  1.000 15.72000 ? 246 ALA D O   1 
ATOM   5149 C CB  . ALA D 1 245 ? -10.50900 8.71200   44.52300  1.000 14.81000 ? 246 ALA D CB  1 
ATOM   5150 N N   . VAL D 1 246 ? -11.18400 5.86900   45.87500  1.000 14.92000 ? 247 VAL D N   1 
ATOM   5151 C CA  . VAL D 1 246 ? -12.10100 5.11700   46.72500  1.000 13.00000 ? 247 VAL D CA  1 
ATOM   5152 C C   . VAL D 1 246 ? -11.79800 5.48700   48.16800  1.000 21.11000 ? 247 VAL D C   1 
ATOM   5153 O O   . VAL D 1 246 ? -10.64800 5.78000   48.52500  1.000 14.59000 ? 247 VAL D O   1 
ATOM   5154 C CB  . VAL D 1 246 ? -11.97600 3.60800   46.47100  1.000 17.24000 ? 247 VAL D CB  1 
ATOM   5155 C CG1 . VAL D 1 246 ? -10.51900 3.13200   46.69100  1.000 13.77000 ? 247 VAL D CG1 1 
ATOM   5156 C CG2 . VAL D 1 246 ? -12.96900 2.79900   47.34200  1.000 29.56000 ? 247 VAL D CG2 1 
ATOM   5157 N N   . VAL D 1 247 ? -12.84700 5.53100   48.98800  1.000 17.68000 ? 248 VAL D N   1 
ATOM   5158 C CA  . VAL D 1 247 ? -12.71800 5.80200   50.42300  1.000 19.90000 ? 248 VAL D CA  1 
ATOM   5159 C C   . VAL D 1 247 ? -12.63800 4.46700   51.15600  1.000 20.11000 ? 248 VAL D C   1 
ATOM   5160 O O   . VAL D 1 247 ? -13.48800 3.58900   50.96900  1.000 20.58000 ? 248 VAL D O   1 
ATOM   5161 C CB  . VAL D 1 247 ? -13.89600 6.64100   50.94100  1.000 20.18000 ? 248 VAL D CB  1 
ATOM   5162 C CG1 . VAL D 1 247 ? -13.84900 6.67300   52.51300  1.000 20.94000 ? 248 VAL D CG1 1 
ATOM   5163 C CG2 . VAL D 1 247 ? -13.83800 8.05400   50.31800  1.000 26.56000 ? 248 VAL D CG2 1 
ATOM   5164 N N   . VAL D 1 248 ? -11.56600 4.26600   51.89700  1.000 16.57000 ? 249 VAL D N   1 
ATOM   5165 C CA  . VAL D 1 248 ? -11.31800 2.95700   52.46900  1.000 18.76000 ? 249 VAL D CA  1 
ATOM   5166 C C   . VAL D 1 248 ? -11.19200 3.05700   53.98800  1.000 22.22000 ? 249 VAL D C   1 
ATOM   5167 O O   . VAL D 1 248 ? -10.79900 4.09100   54.54000  1.000 17.92000 ? 249 VAL D O   1 
ATOM   5168 C CB  . VAL D 1 248 ? -10.07500 2.29100   51.86700  1.000 20.41000 ? 249 VAL D CB  1 
ATOM   5169 C CG1 . VAL D 1 248 ? -10.06200 2.48400   50.35700  1.000 19.82000 ? 249 VAL D CG1 1 
ATOM   5170 C CG2 . VAL D 1 248 ? -8.82100  2.81400   52.49400  1.000 18.28000 ? 249 VAL D CG2 1 
ATOM   5171 N N   . PRO D 1 249 ? -11.51400 1.98700   54.69500  1.000 26.14000 ? 250 PRO D N   1 
ATOM   5172 C CA  . PRO D 1 249 ? -11.37600 2.00800   56.15900  1.000 23.54000 ? 250 PRO D CA  1 
ATOM   5173 C C   . PRO D 1 249 ? -9.90500  2.01800   56.55500  1.000 22.63000 ? 250 PRO D C   1 
ATOM   5174 O O   . PRO D 1 249 ? -9.06600  1.30300   55.97800  1.000 20.95000 ? 250 PRO D O   1 
ATOM   5175 C CB  . PRO D 1 249 ? -12.07800 0.71600   56.60000  1.000 24.90000 ? 250 PRO D CB  1 
ATOM   5176 C CG  . PRO D 1 249 ? -12.96300 0.32300   55.43600  1.000 19.41000 ? 250 PRO D CG  1 
ATOM   5177 C CD  . PRO D 1 249 ? -12.18300 0.77400   54.19800  1.000 18.05000 ? 250 PRO D CD  1 
ATOM   5178 N N   . SER D 1 250 ? -9.58800  2.87000   57.51900  1.000 22.99000 ? 251 SER D N   1 
ATOM   5179 C CA  . SER D 1 250 ? -8.20300  2.99600   57.95200  1.000 21.17000 ? 251 SER D CA  1 
ATOM   5180 C C   . SER D 1 250 ? -7.68500  1.65500   58.41700  1.000 23.39000 ? 251 SER D C   1 
ATOM   5181 O O   . SER D 1 250 ? -8.37500  0.90600   59.10600  1.000 24.95000 ? 251 SER D O   1 
ATOM   5182 C CB  . SER D 1 250 ? -8.10400  4.01300   59.07200  1.000 38.20000 ? 251 SER D CB  1 
ATOM   5183 O OG  . SER D 1 250 ? -8.41400  5.30800   58.56400  1.000 40.87000 ? 251 SER D OG  1 
ATOM   5184 N N   . GLY D 1 251 ? -6.50300  1.31100   57.97700  1.000 20.66000 ? 252 GLY D N   1 
ATOM   5185 C CA  . GLY D 1 251 ? -5.99300  0.00400   58.24300  1.000 23.05000 ? 252 GLY D CA  1 
ATOM   5186 C C   . GLY D 1 251 ? -6.37300  -1.06100  57.24900  1.000 20.12000 ? 252 GLY D C   1 
ATOM   5187 O O   . GLY D 1 251 ? -5.82100  -2.17200  57.34400  1.000 20.75000 ? 252 GLY D O   1 
ATOM   5188 N N   . GLU D 1 252 ? -7.25600  -0.77000  56.27200  1.000 18.19000 ? 253 GLU D N   1 
ATOM   5189 C CA  . GLU D 1 252 ? -7.57600  -1.74600  55.22500  1.000 15.93000 ? 253 GLU D CA  1 
ATOM   5190 C C   . GLU D 1 252 ? -6.98900  -1.39500  53.83300  1.000 18.12000 ? 253 GLU D C   1 
ATOM   5191 O O   . GLU D 1 252 ? -7.28000  -2.10400  52.85900  1.000 16.97000 ? 253 GLU D O   1 
ATOM   5192 C CB  . GLU D 1 252 ? -9.08700  -1.92800  55.17500  1.000 25.54000 ? 253 GLU D CB  1 
ATOM   5193 C CG  . GLU D 1 252 ? -9.45000  -2.71300  56.44800  1.000 25.51000 ? 253 GLU D CG  1 
ATOM   5194 C CD  . GLU D 1 252 ? -10.92000 -2.96500  56.61800  1.000 29.62000 ? 253 GLU D CD  1 
ATOM   5195 O OE1 . GLU D 1 252 ? -11.66600 -2.91400  55.62100  1.000 26.56000 ? 253 GLU D OE1 1 
ATOM   5196 O OE2 . GLU D 1 252 ? -11.29100 -3.26700  57.78200  1.000 31.22000 ? 253 GLU D OE2 1 
ATOM   5197 N N   . GLU D 1 253 ? -6.11300  -0.36800  53.74900  1.000 14.01000 ? 254 GLU D N   1 
ATOM   5198 C CA  . GLU D 1 253 ? -5.46100  0.02200   52.48000  1.000 16.31000 ? 254 GLU D CA  1 
ATOM   5199 C C   . GLU D 1 253 ? -4.90300  -1.15400  51.68700  1.000 15.55000 ? 254 GLU D C   1 
ATOM   5200 O O   . GLU D 1 253 ? -4.93500  -1.16600  50.44900  1.000 16.72000 ? 254 GLU D O   1 
ATOM   5201 C CB  . GLU D 1 253 ? -4.30500  1.00700   52.76100  1.000 13.78000 ? 254 GLU D CB  1 
ATOM   5202 C CG  . GLU D 1 253 ? -4.74400  2.37300   53.12200  1.000 11.26000 ? 254 GLU D CG  1 
ATOM   5203 C CD  . GLU D 1 253 ? -5.05600  2.54200   54.68000  1.000 19.21000 ? 254 GLU D CD  1 
ATOM   5204 O OE1 . GLU D 1 253 ? -5.05200  1.56700   55.45500  1.000 17.39000 ? 254 GLU D OE1 1 
ATOM   5205 O OE2 . GLU D 1 253 ? -5.29900  3.68200   55.08800  1.000 20.53000 ? 254 GLU D OE2 1 
ATOM   5206 N N   . GLN D 1 254 ? -4.31900  -2.13700  52.36700  1.000 17.43000 ? 255 GLN D N   1 
ATOM   5207 C CA  . GLN D 1 254 ? -3.63900  -3.16400  51.59700  1.000 16.48000 ? 255 GLN D CA  1 
ATOM   5208 C C   . GLN D 1 254 ? -4.57000  -4.12500  50.89400  1.000 17.20000 ? 255 GLN D C   1 
ATOM   5209 O O   . GLN D 1 254 ? -4.08300  -4.95700  50.11100  1.000 20.01000 ? 255 GLN D O   1 
ATOM   5210 C CB  . GLN D 1 254 ? -2.69300  -3.94900  52.50600  1.000 21.51000 ? 255 GLN D CB  1 
ATOM   5211 C CG  . GLN D 1 254 ? -1.58500  -3.04000  53.11500  1.000 21.14000 ? 255 GLN D CG  1 
ATOM   5212 C CD  . GLN D 1 254 ? -0.43000  -3.89400  53.67900  1.000 26.60000 ? 255 GLN D CD  1 
ATOM   5213 O OE1 . GLN D 1 254 ? 0.06800   -4.82800  53.01900  1.000 31.44000 ? 255 GLN D OE1 1 
ATOM   5214 N NE2 . GLN D 1 254 ? -0.01200  -3.57600  54.88000  1.000 23.33000 ? 255 GLN D NE2 1 
ATOM   5215 N N   . ARG D 1 255 ? -5.86800  -4.06300  51.16900  1.000 13.53000 ? 256 ARG D N   1 
ATOM   5216 C CA  . ARG D 1 255 ? -6.79800  -4.89300  50.44100  1.000 16.68000 ? 256 ARG D CA  1 
ATOM   5217 C C   . ARG D 1 255 ? -7.13400  -4.34000  49.06000  1.000 20.62000 ? 256 ARG D C   1 
ATOM   5218 O O   . ARG D 1 255 ? -7.77900  -5.03300  48.29000  1.000 18.27000 ? 256 ARG D O   1 
ATOM   5219 C CB  . ARG D 1 255 ? -8.09200  -5.01900  51.23300  1.000 15.81000 ? 256 ARG D CB  1 
ATOM   5220 C CG  . ARG D 1 255 ? -7.84300  -5.67600  52.56300  1.000 24.54000 ? 256 ARG D CG  1 
ATOM   5221 C CD  . ARG D 1 255 ? -9.18000  -6.01500  53.18400  1.000 26.99000 ? 256 ARG D CD  1 
ATOM   5222 N NE  . ARG D 1 255 ? -9.08200  -6.04000  54.63300  1.000 46.42000 ? 256 ARG D NE  1 
ATOM   5223 C CZ  . ARG D 1 255 ? -10.02500 -6.55400  55.39800  1.000 42.41000 ? 256 ARG D CZ  1 
ATOM   5224 N NH1 . ARG D 1 255 ? -11.13600 -7.04600  54.86100  1.000 43.03000 ? 256 ARG D NH1 1 
ATOM   5225 N NH2 . ARG D 1 255 ? -9.84200  -6.58700  56.72200  1.000 40.42000 ? 256 ARG D NH2 1 
ATOM   5226 N N   . TYR D 1 256 ? -6.70200  -3.12500  48.74600  1.000 15.01000 ? 257 TYR D N   1 
ATOM   5227 C CA  . TYR D 1 256 ? -7.10000  -2.42900  47.55000  1.000 14.77000 ? 257 TYR D CA  1 
ATOM   5228 C C   . TYR D 1 256 ? -6.01000  -2.43600  46.48800  1.000 17.76000 ? 257 TYR D C   1 
ATOM   5229 O O   . TYR D 1 256 ? -4.84000  -2.21000  46.78200  1.000 16.48000 ? 257 TYR D O   1 
ATOM   5230 C CB  . TYR D 1 256 ? -7.45200  -1.00700  47.92800  1.000 15.11000 ? 257 TYR D CB  1 
ATOM   5231 C CG  . TYR D 1 256 ? -8.68600  -0.98200  48.71100  1.000 14.54000 ? 257 TYR D CG  1 
ATOM   5232 C CD1 . TYR D 1 256 ? -8.65300  -1.18100  50.11300  1.000 16.37000 ? 257 TYR D CD1 1 
ATOM   5233 C CD2 . TYR D 1 256 ? -9.92000  -0.77200  48.08300  1.000 17.40000 ? 257 TYR D CD2 1 
ATOM   5234 C CE1 . TYR D 1 256 ? -9.83500  -1.08600  50.85700  1.000 17.68000 ? 257 TYR D CE1 1 
ATOM   5235 C CE2 . TYR D 1 256 ? -11.10800 -0.72000  48.83100  1.000 21.02000 ? 257 TYR D CE2 1 
ATOM   5236 C CZ  . TYR D 1 256 ? -11.05000 -0.92500  50.18600  1.000 17.13000 ? 257 TYR D CZ  1 
ATOM   5237 O OH  . TYR D 1 256 ? -12.21300 -0.84000  50.92900  1.000 23.10000 ? 257 TYR D OH  1 
ATOM   5238 N N   . THR D 1 257 ? -6.41500  -2.63800  45.23800  1.000 16.47000 ? 258 THR D N   1 
ATOM   5239 C CA  . THR D 1 257 ? -5.47500  -2.64800  44.13100  1.000 13.93000 ? 258 THR D CA  1 
ATOM   5240 C C   . THR D 1 257 ? -6.08900  -1.78700  43.03200  1.000 13.26000 ? 258 THR D C   1 
ATOM   5241 O O   . THR D 1 257 ? -7.29400  -1.78800  42.84100  1.000 12.43000 ? 258 THR D O   1 
ATOM   5242 C CB  . THR D 1 257 ? -5.20000  -4.09500  43.59900  1.000 18.66000 ? 258 THR D CB  1 
ATOM   5243 O OG1 . THR D 1 257 ? -6.44500  -4.76600  43.37600  1.000 18.30000 ? 258 THR D OG1 1 
ATOM   5244 C CG2 . THR D 1 257 ? -4.35600  -4.94100  44.56900  1.000 18.33000 ? 258 THR D CG2 1 
ATOM   5245 N N   . CYS D 1 258 ? -5.26500  -0.99600  42.36200  1.000 12.16000 ? 259 CYS D N   1 
ATOM   5246 C CA  . CYS D 1 258 ? -5.71800  -0.19600  41.24100  1.000 11.29000 ? 259 CYS D CA  1 
ATOM   5247 C C   . CYS D 1 258 ? -5.22900  -0.84800  39.96000  1.000 13.22000 ? 259 CYS D C   1 
ATOM   5248 O O   . CYS D 1 258 ? -4.09400  -1.30700  39.90400  1.000 16.53000 ? 259 CYS D O   1 
ATOM   5249 C CB  . CYS D 1 258 ? -5.15100  1.22200   41.33400  1.000 14.63000 ? 259 CYS D CB  1 
ATOM   5250 S SG  . CYS D 1 258 ? -5.51900  2.10900   39.83500  1.000 19.17000 ? 259 CYS D SG  1 
ATOM   5251 N N   . HIS D 1 259 ? -6.09600  -0.92300  38.95800  1.000 14.78000 ? 260 HIS D N   1 
ATOM   5252 C CA  . HIS D 1 259 ? -5.85700  -1.68900  37.73600  1.000 16.77000 ? 260 HIS D CA  1 
ATOM   5253 C C   . HIS D 1 259 ? -5.90700  -0.72300  36.56100  1.000 13.76000 ? 260 HIS D C   1 
ATOM   5254 O O   . HIS D 1 259 ? -6.88100  0.02900   36.41800  1.000 13.90000 ? 260 HIS D O   1 
ATOM   5255 C CB  . HIS D 1 259 ? -6.90300  -2.80400  37.59800  1.000 17.07000 ? 260 HIS D CB  1 
ATOM   5256 C CG  . HIS D 1 259 ? -6.85800  -3.72700  38.76900  1.000 18.98000 ? 260 HIS D CG  1 
ATOM   5257 N ND1 . HIS D 1 259 ? -6.16600  -4.92100  38.74100  1.000 27.12000 ? 260 HIS D ND1 1 
ATOM   5258 C CD2 . HIS D 1 259 ? -7.27700  -3.56500  40.05200  1.000 20.87000 ? 260 HIS D CD2 1 
ATOM   5259 C CE1 . HIS D 1 259 ? -6.21500  -5.48500  39.94100  1.000 24.09000 ? 260 HIS D CE1 1 
ATOM   5260 N NE2 . HIS D 1 259 ? -6.90200  -4.69500  40.74500  1.000 21.10000 ? 260 HIS D NE2 1 
ATOM   5261 N N   . VAL D 1 260 ? -4.84600  -0.69200  35.77200  1.000 13.14000 ? 261 VAL D N   1 
ATOM   5262 C CA  . VAL D 1 260 ? -4.68100  0.30200   34.70500  1.000 12.97000 ? 261 VAL D CA  1 
ATOM   5263 C C   . VAL D 1 260 ? -4.52100  -0.44600  33.37600  1.000 15.07000 ? 261 VAL D C   1 
ATOM   5264 O O   . VAL D 1 260 ? -3.60400  -1.26400  33.23400  1.000 16.21000 ? 261 VAL D O   1 
ATOM   5265 C CB  . VAL D 1 260 ? -3.45200  1.18900   34.93100  1.000 14.93000 ? 261 VAL D CB  1 
ATOM   5266 C CG1 . VAL D 1 260 ? -3.37200  2.28000   33.83700  1.000 12.20000 ? 261 VAL D CG1 1 
ATOM   5267 C CG2 . VAL D 1 260 ? -3.46200  1.82300   36.30100  1.000 15.10000 ? 261 VAL D CG2 1 
ATOM   5268 N N   . GLN D 1 261 ? -5.39400  -0.16700  32.41100  1.000 15.31000 ? 262 GLN D N   1 
ATOM   5269 C CA  . GLN D 1 261 ? -5.28000  -0.70300  31.05500  1.000 14.28000 ? 262 GLN D CA  1 
ATOM   5270 C C   . GLN D 1 261 ? -5.07200  0.44500   30.08600  1.000 13.06000 ? 262 GLN D C   1 
ATOM   5271 O O   . GLN D 1 261 ? -5.86600  1.38900   30.08800  1.000 12.01000 ? 262 GLN D O   1 
ATOM   5272 C CB  . GLN D 1 261 ? -6.54300  -1.44000  30.64500  1.000 19.08000 ? 262 GLN D CB  1 
ATOM   5273 C CG  . GLN D 1 261 ? -6.81700  -2.60700  31.59700  1.000 18.16000 ? 262 GLN D CG  1 
ATOM   5274 C CD  . GLN D 1 261 ? -8.17500  -3.18400  31.35100  1.000 30.80000 ? 262 GLN D CD  1 
ATOM   5275 O OE1 . GLN D 1 261 ? -9.09000  -2.93000  32.12000  1.000 36.65000 ? 262 GLN D OE1 1 
ATOM   5276 N NE2 . GLN D 1 261 ? -8.32300  -3.92200  30.27100  1.000 26.43000 ? 262 GLN D NE2 1 
ATOM   5277 N N   . HIS D 1 262 ? -4.03500  0.34800   29.25400  1.000 11.36000 ? 263 HIS D N   1 
ATOM   5278 C CA  . HIS D 1 262 ? -3.79000  1.39200   28.24300  1.000 14.08000 ? 263 HIS D CA  1 
ATOM   5279 C C   . HIS D 1 262 ? -3.01000  0.74400   27.13300  1.000 17.66000 ? 263 HIS D C   1 
ATOM   5280 O O   . HIS D 1 262 ? -2.19900  -0.16200  27.39000  1.000 13.01000 ? 263 HIS D O   1 
ATOM   5281 C CB  . HIS D 1 262 ? -2.98400  2.58600   28.79800  1.000 11.15000 ? 263 HIS D CB  1 
ATOM   5282 C CG  . HIS D 1 262 ? -2.83100  3.72200   27.83100  1.000 12.06000 ? 263 HIS D CG  1 
ATOM   5283 N ND1 . HIS D 1 262 ? -1.74200  3.84100   26.98000  1.000 11.12000 ? 263 HIS D ND1 1 
ATOM   5284 C CD2 . HIS D 1 262 ? -3.60500  4.81700   27.61100  1.000 11.34000 ? 263 HIS D CD2 1 
ATOM   5285 C CE1 . HIS D 1 262 ? -1.84900  4.96600   26.28400  1.000 11.04000 ? 263 HIS D CE1 1 
ATOM   5286 N NE2 . HIS D 1 262 ? -2.99600  5.56100   26.61500  1.000 10.16000 ? 263 HIS D NE2 1 
ATOM   5287 N N   . GLU D 1 263 ? -3.25400  1.22900   25.88900  1.000 11.89000 ? 264 GLU D N   1 
ATOM   5288 C CA  . GLU D 1 263 ? -2.60500  0.65400   24.70300  1.000 14.35000 ? 264 GLU D CA  1 
ATOM   5289 C C   . GLU D 1 263 ? -1.07600  0.70500   24.79400  1.000 17.80000 ? 264 GLU D C   1 
ATOM   5290 O O   . GLU D 1 263 ? -0.38600  -0.13400  24.20300  1.000 20.08000 ? 264 GLU D O   1 
ATOM   5291 C CB  . GLU D 1 263 ? -3.09800  1.45100   23.47800  1.000 17.63000 ? 264 GLU D CB  1 
ATOM   5292 C CG  . GLU D 1 263 ? -2.58400  1.10900   22.20900  1.000 36.41000 ? 264 GLU D CG  1 
ATOM   5293 C CD  . GLU D 1 263 ? -2.95700  2.18900   21.18400  1.000 36.59000 ? 264 GLU D CD  1 
ATOM   5294 O OE1 . GLU D 1 263 ? -4.13800  2.65900   21.14300  1.000 27.55000 ? 264 GLU D OE1 1 
ATOM   5295 O OE2 . GLU D 1 263 ? -2.06500  2.53700   20.39500  1.000 40.74000 ? 264 GLU D OE2 1 
ATOM   5296 N N   . GLY D 1 264 ? -0.52400  1.65200   25.52900  1.000 14.76000 ? 265 GLY D N   1 
ATOM   5297 C CA  . GLY D 1 264 ? 0.93500   1.79800   25.63900  1.000 15.68000 ? 265 GLY D CA  1 
ATOM   5298 C C   . GLY D 1 264 ? 1.57300   0.89400   26.69600  1.000 18.27000 ? 265 GLY D C   1 
ATOM   5299 O O   . GLY D 1 264 ? 2.80000   0.82200   26.81600  1.000 19.07000 ? 265 GLY D O   1 
ATOM   5300 N N   . LEU D 1 265 ? 0.80900   0.21000   27.39000  1.000 14.72000 ? 266 LEU D N   1 
ATOM   5301 C CA  . LEU D 1 265 ? 1.28100   -0.73000  28.41300  1.000 19.12000 ? 266 LEU D CA  1 
ATOM   5302 C C   . LEU D 1 265 ? 1.43600   -2.11800  27.77900  1.000 23.56000 ? 266 LEU D C   1 
ATOM   5303 O O   . LEU D 1 265 ? 0.49000   -2.63800  27.20800  1.000 20.34000 ? 266 LEU D O   1 
ATOM   5304 C CB  . LEU D 1 265 ? 0.28800   -0.83500  29.58100  1.000 14.87000 ? 266 LEU D CB  1 
ATOM   5305 C CG  . LEU D 1 265 ? 0.10600   0.37900   30.49900  1.000 14.53000 ? 266 LEU D CG  1 
ATOM   5306 C CD1 . LEU D 1 265 ? -1.07900  0.28600   31.50700  1.000 16.26000 ? 266 LEU D CD1 1 
ATOM   5307 C CD2 . LEU D 1 265 ? 1.39100   0.61600   31.24000  1.000 20.02000 ? 266 LEU D CD2 1 
ATOM   5308 N N   . PRO D 1 266 ? 2.57500   -2.77100  27.90400  1.000 26.10000 ? 267 PRO D N   1 
ATOM   5309 C CA  . PRO D 1 266 ? 2.66200   -4.13000  27.36700  1.000 29.18000 ? 267 PRO D CA  1 
ATOM   5310 C C   . PRO D 1 266 ? 1.76200   -5.11600  28.11100  1.000 30.19000 ? 267 PRO D C   1 
ATOM   5311 O O   . PRO D 1 266 ? 1.37900   -6.12600  27.53000  1.000 32.27000 ? 267 PRO D O   1 
ATOM   5312 C CB  . PRO D 1 266 ? 4.14500   -4.45200  27.51900  1.000 31.53000 ? 267 PRO D CB  1 
ATOM   5313 C CG  . PRO D 1 266 ? 4.60000   -3.69500  28.75400  1.000 33.66000 ? 267 PRO D CG  1 
ATOM   5314 C CD  . PRO D 1 266 ? 3.80800   -2.34600  28.58900  1.000 30.05000 ? 267 PRO D CD  1 
ATOM   5315 N N   . GLU D 1 267 ? 1.34500   -4.81400  29.35200  1.000 27.77000 ? 268 GLU D N   1 
ATOM   5316 C CA  . GLU D 1 267 ? 0.51400   -5.67500  30.20200  1.000 21.97000 ? 268 GLU D CA  1 
ATOM   5317 C C   . GLU D 1 267 ? -0.22600  -4.70500  31.12200  1.000 18.22000 ? 268 GLU D C   1 
ATOM   5318 O O   . GLU D 1 267 ? 0.34100   -3.66900  31.46800  1.000 20.45000 ? 268 GLU D O   1 
ATOM   5319 C CB  . GLU D 1 267 ? 1.43400   -6.63900  31.00300  1.000 32.12000 ? 268 GLU D CB  1 
ATOM   5320 C CG  . GLU D 1 267 ? 0.88800   -7.21200  32.29500  1.000 42.02000 ? 268 GLU D CG  1 
ATOM   5321 C CD  . GLU D 1 267 ? 1.65300   -8.46000  32.81100  1.000 41.47000 ? 268 GLU D CD  1 
ATOM   5322 O OE1 . GLU D 1 267 ? 2.90800   -8.47400  32.77800  1.000 37.84000 ? 268 GLU D OE1 1 
ATOM   5323 O OE2 . GLU D 1 267 ? 0.97700   -9.40900  33.24200  1.000 43.72000 ? 268 GLU D OE2 1 
ATOM   5324 N N   . PRO D 1 268 ? -1.46900  -4.98200  31.48400  1.000 20.88000 ? 269 PRO D N   1 
ATOM   5325 C CA  . PRO D 1 268 ? -2.17700  -4.13200  32.44300  1.000 21.19000 ? 269 PRO D CA  1 
ATOM   5326 C C   . PRO D 1 268 ? -1.41200  -4.06900  33.75000  1.000 20.95000 ? 269 PRO D C   1 
ATOM   5327 O O   . PRO D 1 268 ? -0.74700  -5.03000  34.13400  1.000 18.58000 ? 269 PRO D O   1 
ATOM   5328 C CB  . PRO D 1 268 ? -3.51100  -4.85700  32.63900  1.000 19.89000 ? 269 PRO D CB  1 
ATOM   5329 C CG  . PRO D 1 268 ? -3.64000  -5.72700  31.42500  1.000 24.50000 ? 269 PRO D CG  1 
ATOM   5330 C CD  . PRO D 1 268 ? -2.30200  -6.08400  30.97800  1.000 21.87000 ? 269 PRO D CD  1 
ATOM   5331 N N   . LEU D 1 269 ? -1.50500  -2.94000  34.43500  1.000 15.40000 ? 270 LEU D N   1 
ATOM   5332 C CA  . LEU D 1 269 ? -0.83100  -2.76800  35.71600  1.000 19.07000 ? 270 LEU D CA  1 
ATOM   5333 C C   . LEU D 1 269 ? -1.74400  -3.05100  36.89400  1.000 22.46000 ? 270 LEU D C   1 
ATOM   5334 O O   . LEU D 1 269 ? -2.94600  -2.76100  36.85800  1.000 19.83000 ? 270 LEU D O   1 
ATOM   5335 C CB  . LEU D 1 269 ? -0.29400  -1.34600  35.92500  1.000 17.00000 ? 270 LEU D CB  1 
ATOM   5336 C CG  . LEU D 1 269 ? 0.63100   -0.88900  34.87500  1.000 22.94000 ? 270 LEU D CG  1 
ATOM   5337 C CD1 . LEU D 1 269 ? 0.90400   0.58200   35.12000  1.000 25.03000 ? 270 LEU D CD1 1 
ATOM   5338 C CD2 . LEU D 1 269 ? 1.88100   -1.69700  35.06700  1.000 24.99000 ? 270 LEU D CD2 1 
ATOM   5339 N N   . THR D 1 270 ? -1.11200  -3.45600  38.00400  1.000 15.95000 ? 271 THR D N   1 
ATOM   5340 C CA  . THR D 1 270 ? -1.77600  -3.61900  39.30100  1.000 17.38000 ? 271 THR D CA  1 
ATOM   5341 C C   . THR D 1 270 ? -0.93700  -2.81300  40.28500  1.000 21.96000 ? 271 THR D C   1 
ATOM   5342 O O   . THR D 1 270 ? 0.23600   -3.13500  40.50300  1.000 25.89000 ? 271 THR D O   1 
ATOM   5343 C CB  . THR D 1 270 ? -1.86300  -5.10100  39.72400  1.000 23.16000 ? 271 THR D CB  1 
ATOM   5344 O OG1 . THR D 1 270 ? -2.61000  -5.83900  38.75000  1.000 20.64000 ? 271 THR D OG1 1 
ATOM   5345 C CG2 . THR D 1 270 ? -2.61000  -5.24200  41.08900  1.000 22.62000 ? 271 THR D CG2 1 
ATOM   5346 N N   . LEU D 1 271 ? -1.48800  -1.71400  40.79400  1.000 19.39000 ? 272 LEU D N   1 
ATOM   5347 C CA  . LEU D 1 271 ? -0.79000  -0.83100  41.72100  1.000 17.64000 ? 272 LEU D CA  1 
ATOM   5348 C C   . LEU D 1 271 ? -1.39000  -0.92900  43.10800  1.000 17.23000 ? 272 LEU D C   1 
ATOM   5349 O O   . LEU D 1 271 ? -2.57300  -1.20800  43.26600  1.000 17.18000 ? 272 LEU D O   1 
ATOM   5350 C CB  . LEU D 1 271 ? -0.87200  0.65000   41.36400  1.000 15.57000 ? 272 LEU D CB  1 
ATOM   5351 C CG  . LEU D 1 271 ? -0.41100  1.12800   40.02000  1.000 29.30000 ? 272 LEU D CG  1 
ATOM   5352 C CD1 . LEU D 1 271 ? -1.29300  0.67500   39.00700  1.000 27.04000 ? 272 LEU D CD1 1 
ATOM   5353 C CD2 . LEU D 1 271 ? -0.41500  2.62800   40.12300  1.000 29.48000 ? 272 LEU D CD2 1 
ATOM   5354 N N   . ARG D 1 272 ? -0.56900  -0.65700  44.10400  1.000 13.37000 ? 273 ARG D N   1 
ATOM   5355 C CA  . ARG D 1 272 ? -1.00200  -0.72200  45.50100  1.000 13.51000 ? 273 ARG D CA  1 
ATOM   5356 C C   . ARG D 1 272 ? -0.44000  0.48100   46.19700  1.000 21.95000 ? 273 ARG D C   1 
ATOM   5357 O O   . ARG D 1 272 ? 0.64900   0.96600   45.83600  1.000 16.89000 ? 273 ARG D O   1 
ATOM   5358 C CB  . ARG D 1 272 ? -0.48700  -1.96800  46.21000  1.000 21.78000 ? 273 ARG D CB  1 
ATOM   5359 C CG  . ARG D 1 272 ? -1.33700  -3.18800  46.00800  1.000 21.38000 ? 273 ARG D CG  1 
ATOM   5360 C CD  . ARG D 1 272 ? -0.64900  -4.35700  46.69500  1.000 30.37000 ? 273 ARG D CD  1 
ATOM   5361 N NE  . ARG D 1 272 ? -1.35600  -5.61900  46.49800  1.000 29.45000 ? 273 ARG D NE  1 
ATOM   5362 C CZ  . ARG D 1 272 ? -1.23100  -6.36000  45.41500  1.000 37.01000 ? 273 ARG D CZ  1 
ATOM   5363 N NH1 . ARG D 1 272 ? -0.44700  -5.98300  44.42000  1.000 32.54000 ? 273 ARG D NH1 1 
ATOM   5364 N NH2 . ARG D 1 272 ? -1.91900  -7.49500  45.32400  1.000 38.89000 ? 273 ARG D NH2 1 
ATOM   5365 N N   . TRP D 1 273 ? -1.15800  0.94400   47.21800  1.000 12.14000 ? 274 TRP D N   1 
ATOM   5366 C CA  . TRP D 1 273 ? -0.52400  1.86000   48.15300  1.000 13.40000 ? 274 TRP D CA  1 
ATOM   5367 C C   . TRP D 1 273 ? 0.58600   1.12500   49.01200  1.000 15.30000 ? 274 TRP D C   1 
ATOM   5368 O O   . TRP D 1 273 ? 1.68400   1.82200   49.11600  1.000 14.63000 ? 274 TRP D O   1 
ATOM   5369 C CB  . TRP D 1 273 ? -1.55100  2.46700   49.07800  1.000 14.22000 ? 274 TRP D CB  1 
ATOM   5370 C CG  . TRP D 1 273 ? -1.02200  3.32800   50.21200  1.000 12.20000 ? 274 TRP D CG  1 
ATOM   5371 C CD1 . TRP D 1 273 ? -1.14800  3.08400   51.56600  1.000 14.14000 ? 274 TRP D CD1 1 
ATOM   5372 C CD2 . TRP D 1 273 ? -0.36700  4.59200   50.10100  1.000 13.70000 ? 274 TRP D CD2 1 
ATOM   5373 N NE1 . TRP D 1 273 ? -0.62200  4.13500   52.30100  1.000 13.14000 ? 274 TRP D NE1 1 
ATOM   5374 C CE2 . TRP D 1 273 ? -0.11500  5.06000   51.42400  1.000 11.79000 ? 274 TRP D CE2 1 
ATOM   5375 C CE3 . TRP D 1 273 ? 0.01100   5.38400   49.02900  1.000 13.00000 ? 274 TRP D CE3 1 
ATOM   5376 C CZ2 . TRP D 1 273 ? 0.53300   6.27300   51.68100  1.000 13.36000 ? 274 TRP D CZ2 1 
ATOM   5377 C CZ3 . TRP D 1 273 ? 0.66900   6.59100   49.29700  1.000 15.43000 ? 274 TRP D CZ3 1 
ATOM   5378 C CH2 . TRP D 1 273 ? 0.92400   7.01000   50.59200  1.000 13.95000 ? 274 TRP D CH2 1 
ATOM   5379 N N   . ILE E 2 1   ? -31.49800 20.49300  25.11500  1.000 51.31000 ? 1   ILE E N   1 
ATOM   5380 C CA  . ILE E 2 1   ? -31.22000 21.87700  24.85200  1.000 41.67000 ? 1   ILE E CA  1 
ATOM   5381 C C   . ILE E 2 1   ? -30.27200 22.50100  25.87600  1.000 28.30000 ? 1   ILE E C   1 
ATOM   5382 O O   . ILE E 2 1   ? -29.34500 23.18400  25.43900  1.000 31.05000 ? 1   ILE E O   1 
ATOM   5383 C CB  . ILE E 2 1   ? -32.51100 22.69400  24.63700  1.000 32.30000 ? 1   ILE E CB  1 
ATOM   5384 C CG1 . ILE E 2 1   ? -33.33500 22.73000  25.90700  1.000 31.68000 ? 1   ILE E CG1 1 
ATOM   5385 C CG2 . ILE E 2 1   ? -33.12800 22.37900  23.23800  1.000 38.12000 ? 1   ILE E CG2 1 
ATOM   5386 C CD1 . ILE E 2 1   ? -33.99400 24.07500  26.13400  1.000 41.29000 ? 1   ILE E CD1 1 
ATOM   5387 N N   . GLN E 2 2   ? -30.40600 22.32300  27.21900  1.000 25.12000 ? 2   GLN E N   1 
ATOM   5388 C CA  . GLN E 2 2   ? -29.38000 22.97400  28.07400  1.000 28.55000 ? 2   GLN E CA  1 
ATOM   5389 C C   . GLN E 2 2   ? -28.68300 22.02200  29.03500  1.000 26.97000 ? 2   GLN E C   1 
ATOM   5390 O O   . GLN E 2 2   ? -29.34800 21.30700  29.77600  1.000 26.46000 ? 2   GLN E O   1 
ATOM   5391 C CB  . GLN E 2 2   ? -29.93600 24.16600  28.85900  1.000 32.31000 ? 2   GLN E CB  1 
ATOM   5392 C CG  . GLN E 2 2   ? -30.04400 25.44500  28.01700  1.000 29.91000 ? 2   GLN E CG  1 
ATOM   5393 C CD  . GLN E 2 2   ? -30.71500 26.60200  28.76600  1.000 41.88000 ? 2   GLN E CD  1 
ATOM   5394 O OE1 . GLN E 2 2   ? -31.06000 26.49900  29.95100  1.000 45.43000 ? 2   GLN E OE1 1 
ATOM   5395 N NE2 . GLN E 2 2   ? -30.84100 27.73300  28.08500  1.000 43.09000 ? 2   GLN E NE2 1 
ATOM   5396 N N   . ARG E 2 3   ? -27.34500 22.02300  29.03300  1.000 20.42000 ? 3   ARG E N   1 
ATOM   5397 C CA  . ARG E 2 3   ? -26.53500 21.17100  29.92000  1.000 17.04000 ? 3   ARG E CA  1 
ATOM   5398 C C   . ARG E 2 3   ? -25.49100 21.98800  30.66000  1.000 20.80000 ? 3   ARG E C   1 
ATOM   5399 O O   . ARG E 2 3   ? -24.76200 22.78600  30.05100  1.000 15.61000 ? 3   ARG E O   1 
ATOM   5400 C CB  . ARG E 2 3   ? -25.82100 20.05800  29.15400  1.000 20.27000 ? 3   ARG E CB  1 
ATOM   5401 C CG  . ARG E 2 3   ? -26.81000 19.10700  28.44600  1.000 24.87000 ? 3   ARG E CG  1 
ATOM   5402 C CD  . ARG E 2 3   ? -26.16100 18.07900  27.56600  1.000 28.39000 ? 3   ARG E CD  1 
ATOM   5403 N NE  . ARG E 2 3   ? -26.80900 18.18000  26.25400  1.000 46.55000 ? 3   ARG E NE  1 
ATOM   5404 C CZ  . ARG E 2 3   ? -26.29700 17.74100  25.11000  1.000 43.53000 ? 3   ARG E CZ  1 
ATOM   5405 N NH1 . ARG E 2 3   ? -25.15500 17.09100  25.09100  1.000 30.74000 ? 3   ARG E NH1 1 
ATOM   5406 N NH2 . ARG E 2 3   ? -26.96300 17.95900  23.95300  1.000 29.10000 ? 3   ARG E NH2 1 
ATOM   5407 N N   . THR E 2 4   ? -25.39300 21.77200  31.93600  1.000 15.15000 ? 4   THR E N   1 
ATOM   5408 C CA  . THR E 2 4   ? -24.51400 22.63800  32.70900  1.000 13.54000 ? 4   THR E CA  1 
ATOM   5409 C C   . THR E 2 4   ? -23.07100 22.11100  32.71700  1.000 13.99000 ? 4   THR E C   1 
ATOM   5410 O O   . THR E 2 4   ? -22.83100 20.91000  32.62000  1.000 14.66000 ? 4   THR E O   1 
ATOM   5411 C CB  . THR E 2 4   ? -25.06500 22.73500  34.13700  1.000 23.63000 ? 4   THR E CB  1 
ATOM   5412 O OG1 . THR E 2 4   ? -24.54400 23.90100  34.76800  1.000 28.83000 ? 4   THR E OG1 1 
ATOM   5413 C CG2 . THR E 2 4   ? -24.70500 21.49100  34.89400  1.000 21.82000 ? 4   THR E CG2 1 
ATOM   5414 N N   . PRO E 2 5   ? -22.03900 22.95300  32.76300  1.000 18.97000 ? 5   PRO E N   1 
ATOM   5415 C CA  . PRO E 2 5   ? -20.67200 22.44900  32.56200  1.000 14.76000 ? 5   PRO E CA  1 
ATOM   5416 C C   . PRO E 2 5   ? -20.13800 21.68300  33.75200  1.000 18.26000 ? 5   PRO E C   1 
ATOM   5417 O O   . PRO E 2 5   ? -20.39400 22.03800  34.90900  1.000 16.26000 ? 5   PRO E O   1 
ATOM   5418 C CB  . PRO E 2 5   ? -19.85600 23.72600  32.36400  1.000 16.32000 ? 5   PRO E CB  1 
ATOM   5419 C CG  . PRO E 2 5   ? -20.70100 24.80700  33.04900  1.000 14.40000 ? 5   PRO E CG  1 
ATOM   5420 C CD  . PRO E 2 5   ? -22.09400 24.42500  32.76800  1.000 15.47000 ? 5   PRO E CD  1 
ATOM   5421 N N   . LYS E 2 6   ? -19.38400 20.63000  33.45700  1.000 12.59000 ? 6   LYS E N   1 
ATOM   5422 C CA  . LYS E 2 6   ? -18.48300 20.01500  34.43200  1.000 16.18000 ? 6   LYS E CA  1 
ATOM   5423 C C   . LYS E 2 6   ? -17.23300 20.85100  34.44700  1.000 15.72000 ? 6   LYS E C   1 
ATOM   5424 O O   . LYS E 2 6   ? -16.90600 21.47700  33.43700  1.000 15.63000 ? 6   LYS E O   1 
ATOM   5425 C CB  . LYS E 2 6   ? -18.15100 18.55400  34.02300  1.000 13.99000 ? 6   LYS E CB  1 
ATOM   5426 C CG  . LYS E 2 6   ? -19.41400 17.63800  34.05400  1.000 17.70000 ? 6   LYS E CG  1 
ATOM   5427 C CD  . LYS E 2 6   ? -19.19500 16.26300  33.32800  1.000 30.25000 ? 6   LYS E CD  1 
ATOM   5428 C CE  . LYS E 2 6   ? -18.66700 16.46800  31.88300  1.000 38.62000 ? 6   LYS E CE  1 
ATOM   5429 N NZ  . LYS E 2 6   ? -18.23600 15.26700  31.04300  1.000 42.63000 ? 6   LYS E NZ  1 
ATOM   5430 N N   . ILE E 2 7   ? -16.50600 20.81800  35.57200  1.000 13.56000 ? 7   ILE E N   1 
ATOM   5431 C CA  . ILE E 2 7   ? -15.36300 21.69100  35.78300  1.000 11.00000 ? 7   ILE E CA  1 
ATOM   5432 C C   . ILE E 2 7   ? -14.29200 20.88200  36.51200  1.000 15.86000 ? 7   ILE E C   1 
ATOM   5433 O O   . ILE E 2 7   ? -14.57000 20.23700  37.54000  1.000 15.29000 ? 7   ILE E O   1 
ATOM   5434 C CB  . ILE E 2 7   ? -15.73200 22.95300  36.60200  1.000 9.58000  ? 7   ILE E CB  1 
ATOM   5435 C CG1 . ILE E 2 7   ? -16.84800 23.72600  35.95200  1.000 13.53000 ? 7   ILE E CG1 1 
ATOM   5436 C CG2 . ILE E 2 7   ? -14.47600 23.83100  36.82400  1.000 13.47000 ? 7   ILE E CG2 1 
ATOM   5437 C CD1 . ILE E 2 7   ? -17.59600 24.72700  36.95500  1.000 14.21000 ? 7   ILE E CD1 1 
ATOM   5438 N N   . GLN E 2 8   ? -13.08600 20.90000  35.97300  1.000 11.78000 ? 8   GLN E N   1 
ATOM   5439 C CA  . GLN E 2 8   ? -11.91600 20.34700  36.67200  1.000 15.26000 ? 8   GLN E CA  1 
ATOM   5440 C C   . GLN E 2 8   ? -10.83700 21.40100  36.57500  1.000 14.70000 ? 8   GLN E C   1 
ATOM   5441 O O   . GLN E 2 8   ? -10.57500 21.90700  35.48100  1.000 12.20000 ? 8   GLN E O   1 
ATOM   5442 C CB  . GLN E 2 8   ? -11.40500 19.03900  36.05000  1.000 10.73000 ? 8   GLN E CB  1 
ATOM   5443 C CG  . GLN E 2 8   ? -12.34000 17.89700  36.12600  1.000 11.78000 ? 8   GLN E CG  1 
ATOM   5444 C CD  . GLN E 2 8   ? -11.64500 16.57800  35.82500  1.000 13.31000 ? 8   GLN E CD  1 
ATOM   5445 O OE1 . GLN E 2 8   ? -10.79500 16.13600  36.58600  1.000 14.28000 ? 8   GLN E OE1 1 
ATOM   5446 N NE2 . GLN E 2 8   ? -12.00100 15.93300  34.71000  1.000 14.98000 ? 8   GLN E NE2 1 
ATOM   5447 N N   . VAL E 2 9   ? -10.21600 21.71900  37.71300  1.000 11.25000 ? 9   VAL E N   1 
ATOM   5448 C CA  . VAL E 2 9   ? -9.09700  22.65600  37.81500  1.000 9.62000  ? 9   VAL E CA  1 
ATOM   5449 C C   . VAL E 2 9   ? -7.90700  21.86400  38.32000  1.000 10.73000 ? 9   VAL E C   1 
ATOM   5450 O O   . VAL E 2 9   ? -8.02300  21.18500  39.33000  1.000 12.99000 ? 9   VAL E O   1 
ATOM   5451 C CB  . VAL E 2 9   ? -9.39000  23.79200  38.80800  1.000 19.29000 ? 9   VAL E CB  1 
ATOM   5452 C CG1 . VAL E 2 9   ? -8.35700  24.86800  38.67400  1.000 14.50000 ? 9   VAL E CG1 1 
ATOM   5453 C CG2 . VAL E 2 9   ? -10.79900 24.34200  38.54300  1.000 18.25000 ? 9   VAL E CG2 1 
ATOM   5454 N N   . TYR E 2 10  ? -6.78300  21.96400  37.64400  1.000 10.76000 ? 10  TYR E N   1 
ATOM   5455 C CA  . TYR E 2 10  ? -5.68000  21.04500  37.92500  1.000 15.92000 ? 10  TYR E CA  1 
ATOM   5456 C C   . TYR E 2 10  ? -4.42900  21.60500  37.25400  1.000 13.64000 ? 10  TYR E C   1 
ATOM   5457 O O   . TYR E 2 10  ? -4.50500  22.50200  36.40000  1.000 15.48000 ? 10  TYR E O   1 
ATOM   5458 C CB  . TYR E 2 10  ? -5.97800  19.61300  37.42300  1.000 14.02000 ? 10  TYR E CB  1 
ATOM   5459 C CG  . TYR E 2 10  ? -6.31700  19.56800  35.92300  1.000 13.61000 ? 10  TYR E CG  1 
ATOM   5460 C CD1 . TYR E 2 10  ? -7.57100  19.95900  35.49200  1.000 14.37000 ? 10  TYR E CD1 1 
ATOM   5461 C CD2 . TYR E 2 10  ? -5.37100  19.11500  34.95200  1.000 11.71000 ? 10  TYR E CD2 1 
ATOM   5462 C CE1 . TYR E 2 10  ? -7.92300  19.91500  34.18700  1.000 11.55000 ? 10  TYR E CE1 1 
ATOM   5463 C CE2 . TYR E 2 10  ? -5.72900  19.07300  33.58200  1.000 10.79000 ? 10  TYR E CE2 1 
ATOM   5464 C CZ  . TYR E 2 10  ? -6.98800  19.48900  33.23300  1.000 12.11000 ? 10  TYR E CZ  1 
ATOM   5465 O OH  . TYR E 2 10  ? -7.39200  19.44100  31.92700  1.000 13.61000 ? 10  TYR E OH  1 
ATOM   5466 N N   . SER E 2 11  ? -3.27200  21.01900  37.57600  1.000 14.91000 ? 11  SER E N   1 
ATOM   5467 C CA  . SER E 2 11  ? -2.03500  21.50100  36.97900  1.000 12.67000 ? 11  SER E CA  1 
ATOM   5468 C C   . SER E 2 11  ? -1.52600  20.49500  35.94900  1.000 16.02000 ? 11  SER E C   1 
ATOM   5469 O O   . SER E 2 11  ? -1.81800  19.29600  36.02500  1.000 17.93000 ? 11  SER E O   1 
ATOM   5470 C CB  . SER E 2 11  ? -0.93200  21.76000  38.02100  1.000 14.58000 ? 11  SER E CB  1 
ATOM   5471 O OG  . SER E 2 11  ? -0.75300  20.53200  38.74000  1.000 19.32000 ? 11  SER E OG  1 
ATOM   5472 N N   . ARG E 2 12  ? -0.78300  20.99500  34.96800  1.000 14.87000 ? 12  ARG E N   1 
ATOM   5473 C CA  . ARG E 2 12  ? -0.29900  20.11200  33.91500  1.000 14.42000 ? 12  ARG E CA  1 
ATOM   5474 C C   . ARG E 2 12  ? 0.61500   19.03800  34.48900  1.000 20.22000 ? 12  ARG E C   1 
ATOM   5475 O O   . ARG E 2 12  ? 0.55200   17.85800  34.09300  1.000 16.59000 ? 12  ARG E O   1 
ATOM   5476 C CB  . ARG E 2 12  ? 0.45600   20.90900  32.85300  1.000 13.28000 ? 12  ARG E CB  1 
ATOM   5477 C CG  . ARG E 2 12  ? 1.08000   20.03200  31.75100  1.000 18.51000 ? 12  ARG E CG  1 
ATOM   5478 C CD  . ARG E 2 12  ? 1.79400   20.87600  30.71500  1.000 16.38000 ? 12  ARG E CD  1 
ATOM   5479 N NE  . ARG E 2 12  ? 0.91500   21.83700  30.02600  1.000 15.76000 ? 12  ARG E NE  1 
ATOM   5480 C CZ  . ARG E 2 12  ? 1.37600   22.68100  29.11500  1.000 21.49000 ? 12  ARG E CZ  1 
ATOM   5481 N NH1 . ARG E 2 12  ? 2.66200   22.70000  28.77700  1.000 20.43000 ? 12  ARG E NH1 1 
ATOM   5482 N NH2 . ARG E 2 12  ? 0.54000   23.50600  28.49600  1.000 17.99000 ? 12  ARG E NH2 1 
ATOM   5483 N N   . HIS E 2 13  ? 1.48400   19.44200  35.38200  1.000 16.72000 ? 13  HIS E N   1 
ATOM   5484 C CA  . HIS E 2 13  ? 2.44000   18.58200  36.08800  1.000 21.07000 ? 13  HIS E CA  1 
ATOM   5485 C C   . HIS E 2 13  ? 2.14500   18.56800  37.57200  1.000 20.68000 ? 13  HIS E C   1 
ATOM   5486 O O   . HIS E 2 13  ? 1.58600   19.55100  38.08800  1.000 18.68000 ? 13  HIS E O   1 
ATOM   5487 C CB  . HIS E 2 13  ? 3.86000   19.09500  35.86700  1.000 19.99000 ? 13  HIS E CB  1 
ATOM   5488 C CG  . HIS E 2 13  ? 4.18200   19.26000  34.43200  1.000 20.78000 ? 13  HIS E CG  1 
ATOM   5489 N ND1 . HIS E 2 13  ? 4.22800   18.18500  33.57500  1.000 18.74000 ? 13  HIS E ND1 1 
ATOM   5490 C CD2 . HIS E 2 13  ? 4.46900   20.36200  33.68900  1.000 18.07000 ? 13  HIS E CD2 1 
ATOM   5491 C CE1 . HIS E 2 13  ? 4.55800   18.61000  32.36800  1.000 21.16000 ? 13  HIS E CE1 1 
ATOM   5492 N NE2 . HIS E 2 13  ? 4.69200   19.92900  32.40200  1.000 21.16000 ? 13  HIS E NE2 1 
ATOM   5493 N N   . PRO E 2 14  ? 2.46300   17.46700  38.28700  1.000 28.33000 ? 14  PRO E N   1 
ATOM   5494 C CA  . PRO E 2 14  ? 2.22600   17.44700  39.74400  1.000 20.32000 ? 14  PRO E CA  1 
ATOM   5495 C C   . PRO E 2 14  ? 2.91800   18.65100  40.37800  1.000 15.63000 ? 14  PRO E C   1 
ATOM   5496 O O   . PRO E 2 14  ? 4.00800   19.02300  39.99300  1.000 20.45000 ? 14  PRO E O   1 
ATOM   5497 C CB  . PRO E 2 14  ? 2.82000   16.10900  40.19800  1.000 32.55000 ? 14  PRO E CB  1 
ATOM   5498 C CG  . PRO E 2 14  ? 2.80800   15.20300  38.92200  1.000 23.95000 ? 14  PRO E CG  1 
ATOM   5499 C CD  . PRO E 2 14  ? 3.01500   16.18000  37.77200  1.000 25.13000 ? 14  PRO E CD  1 
ATOM   5500 N N   . ALA E 2 15  ? 2.20100   19.33800  41.24500  1.000 19.72000 ? 15  ALA E N   1 
ATOM   5501 C CA  . ALA E 2 15  ? 2.62600   20.67400  41.63700  1.000 21.09000 ? 15  ALA E CA  1 
ATOM   5502 C C   . ALA E 2 15  ? 3.72600   20.56500  42.67200  1.000 22.01000 ? 15  ALA E C   1 
ATOM   5503 O O   . ALA E 2 15  ? 3.73800   19.65300  43.50400  1.000 21.78000 ? 15  ALA E O   1 
ATOM   5504 C CB  . ALA E 2 15  ? 1.48500   21.49600  42.21500  1.000 25.33000 ? 15  ALA E CB  1 
ATOM   5505 N N   . GLU E 2 16  ? 4.61700   21.51500  42.61300  1.000 22.13000 ? 16  GLU E N   1 
ATOM   5506 C CA  . GLU E 2 16  ? 5.68300   21.65300  43.57900  1.000 28.86000 ? 16  GLU E CA  1 
ATOM   5507 C C   . GLU E 2 16  ? 5.94300   23.13100  43.78300  1.000 20.54000 ? 16  GLU E C   1 
ATOM   5508 O O   . GLU E 2 16  ? 6.19800   23.85300  42.81700  1.000 24.52000 ? 16  GLU E O   1 
ATOM   5509 C CB  . GLU E 2 16  ? 6.93800   20.94800  43.08100  1.000 27.92000 ? 16  GLU E CB  1 
ATOM   5510 C CG  . GLU E 2 16  ? 7.92800   20.74900  44.19800  1.000 33.60000 ? 16  GLU E CG  1 
ATOM   5511 C CD  . GLU E 2 16  ? 9.19000   20.07700  43.71600  1.000 37.75000 ? 16  GLU E CD  1 
ATOM   5512 O OE1 . GLU E 2 16  ? 9.40800   19.98200  42.49000  1.000 33.58000 ? 16  GLU E OE1 1 
ATOM   5513 O OE2 . GLU E 2 16  ? 10.02100  19.77200  44.62100  1.000 31.58000 ? 16  GLU E OE2 1 
ATOM   5514 N N   . ASN E 2 17  ? 5.87800   23.56400  45.03600  1.000 27.17000 ? 17  ASN E N   1 
ATOM   5515 C CA  . ASN E 2 17  ? 5.98400   24.99300  45.32200  1.000 28.27000 ? 17  ASN E CA  1 
ATOM   5516 C C   . ASN E 2 17  ? 7.28100   25.56200  44.77800  1.000 31.59000 ? 17  ASN E C   1 
ATOM   5517 O O   . ASN E 2 17  ? 8.34900   24.94700  44.89000  1.000 24.42000 ? 17  ASN E O   1 
ATOM   5518 C CB  . ASN E 2 17  ? 5.87900   25.24300  46.82600  1.000 24.98000 ? 17  ASN E CB  1 
ATOM   5519 C CG  . ASN E 2 17  ? 4.57100   24.84800  47.35400  1.000 36.51000 ? 17  ASN E CG  1 
ATOM   5520 O OD1 . ASN E 2 17  ? 3.51400   25.03400  46.69500  1.000 29.82000 ? 17  ASN E OD1 1 
ATOM   5521 N ND2 . ASN E 2 17  ? 4.58100   24.28200  48.54400  1.000 31.75000 ? 17  ASN E ND2 1 
ATOM   5522 N N   . GLY E 2 18  ? 7.18200   26.72100  44.13700  1.000 26.49000 ? 18  GLY E N   1 
ATOM   5523 C CA  . GLY E 2 18  ? 8.33900   27.33000  43.52000  1.000 23.04000 ? 18  GLY E CA  1 
ATOM   5524 C C   . GLY E 2 18  ? 8.71300   26.80900  42.14700  1.000 32.02000 ? 18  GLY E C   1 
ATOM   5525 O O   . GLY E 2 18  ? 9.62100   27.36400  41.53200  1.000 27.29000 ? 18  GLY E O   1 
ATOM   5526 N N   . LYS E 2 19  ? 8.01200   25.80900  41.60300  1.000 27.45000 ? 19  LYS E N   1 
ATOM   5527 C CA  . LYS E 2 19  ? 8.32400   25.30100  40.26000  1.000 27.79000 ? 19  LYS E CA  1 
ATOM   5528 C C   . LYS E 2 19  ? 7.26200   25.75000  39.25200  1.000 25.19000 ? 19  LYS E C   1 
ATOM   5529 O O   . LYS E 2 19  ? 6.05400   25.58500  39.49800  1.000 18.93000 ? 19  LYS E O   1 
ATOM   5530 C CB  . LYS E 2 19  ? 8.38100   23.78200  40.26800  1.000 25.57000 ? 19  LYS E CB  1 
ATOM   5531 C CG  . LYS E 2 19  ? 9.40900   23.21300  41.30600  1.000 33.62000 ? 19  LYS E CG  1 
ATOM   5532 C CD  . LYS E 2 19  ? 10.78200  23.25800  40.69700  1.000 34.20000 ? 19  LYS E CD  1 
ATOM   5533 C CE  . LYS E 2 19  ? 11.86000  22.67900  41.63300  1.000 40.20000 ? 19  LYS E CE  1 
ATOM   5534 N NZ  . LYS E 2 19  ? 13.15700  22.33400  40.89100  1.000 30.11000 ? 19  LYS E NZ  1 
ATOM   5535 N N   . SER E 2 20  ? 7.70200   26.29900  38.13300  1.000 22.40000 ? 20  SER E N   1 
ATOM   5536 C CA  . SER E 2 20  ? 6.73200   26.78300  37.15800  1.000 25.44000 ? 20  SER E CA  1 
ATOM   5537 C C   . SER E 2 20  ? 6.01000   25.60600  36.51900  1.000 23.80000 ? 20  SER E C   1 
ATOM   5538 O O   . SER E 2 20  ? 6.53900   24.49300  36.43400  1.000 20.06000 ? 20  SER E O   1 
ATOM   5539 C CB  . SER E 2 20  ? 7.39200   27.59500  36.06500  1.000 25.98000 ? 20  SER E CB  1 
ATOM   5540 O OG  . SER E 2 20  ? 8.26600   26.72000  35.42100  1.000 33.64000 ? 20  SER E OG  1 
ATOM   5541 N N   . ASN E 2 21  ? 4.80900   25.88400  36.01400  1.000 23.25000 ? 21  ASN E N   1 
ATOM   5542 C CA  . ASN E 2 21  ? 3.81200   24.85800  35.73100  1.000 17.27000 ? 21  ASN E CA  1 
ATOM   5543 C C   . ASN E 2 21  ? 2.71900   25.52400  34.90000  1.000 19.69000 ? 21  ASN E C   1 
ATOM   5544 O O   . ASN E 2 21  ? 2.83700   26.68600  34.45600  1.000 15.28000 ? 21  ASN E O   1 
ATOM   5545 C CB  . ASN E 2 21  ? 3.27700   24.26400  37.04400  1.000 14.71000 ? 21  ASN E CB  1 
ATOM   5546 C CG  . ASN E 2 21  ? 2.75800   22.83400  36.92800  1.000 17.86000 ? 21  ASN E CG  1 
ATOM   5547 O OD1 . ASN E 2 21  ? 2.29800   22.38600  35.85500  1.000 19.36000 ? 21  ASN E OD1 1 
ATOM   5548 N ND2 . ASN E 2 21  ? 2.65600   22.15900  38.10000  1.000 16.25000 ? 21  ASN E ND2 1 
ATOM   5549 N N   . PHE E 2 22  ? 1.65900   24.77400  34.66300  1.000 14.49000 ? 22  PHE E N   1 
ATOM   5550 C CA  . PHE E 2 22  ? 0.53400   25.37200  33.94200  1.000 15.07000 ? 22  PHE E CA  1 
ATOM   5551 C C   . PHE E 2 22  ? -0.70300  25.04100  34.73800  1.000 12.35000 ? 22  PHE E C   1 
ATOM   5552 O O   . PHE E 2 22  ? -0.85600  23.89900  35.17800  1.000 15.78000 ? 22  PHE E O   1 
ATOM   5553 C CB  . PHE E 2 22  ? 0.37400   24.83100  32.50100  1.000 17.54000 ? 22  PHE E CB  1 
ATOM   5554 C CG  . PHE E 2 22  ? 1.35300   25.41100  31.52600  1.000 22.98000 ? 22  PHE E CG  1 
ATOM   5555 C CD1 . PHE E 2 22  ? 2.59700   24.85100  31.37300  1.000 22.32000 ? 22  PHE E CD1 1 
ATOM   5556 C CD2 . PHE E 2 22  ? 0.99900   26.52100  30.77300  1.000 21.58000 ? 22  PHE E CD2 1 
ATOM   5557 C CE1 . PHE E 2 22  ? 3.53400   25.40100  30.46800  1.000 26.70000 ? 22  PHE E CE1 1 
ATOM   5558 C CE2 . PHE E 2 22  ? 1.90500   27.06600  29.87200  1.000 31.90000 ? 22  PHE E CE2 1 
ATOM   5559 C CZ  . PHE E 2 22  ? 3.18200   26.47500  29.72600  1.000 29.43000 ? 22  PHE E CZ  1 
ATOM   5560 N N   . LEU E 2 23  ? -1.57600  26.03200  34.90300  1.000 11.08000 ? 23  LEU E N   1 
ATOM   5561 C CA  . LEU E 2 23  ? -2.83900  25.88700  35.60200  1.000 14.05000 ? 23  LEU E CA  1 
ATOM   5562 C C   . LEU E 2 23  ? -3.92500  25.71900  34.56700  1.000 14.13000 ? 23  LEU E C   1 
ATOM   5563 O O   . LEU E 2 23  ? -4.02900  26.53200  33.65500  1.000 12.78000 ? 23  LEU E O   1 
ATOM   5564 C CB  . LEU E 2 23  ? -3.10600  27.12300  36.45800  1.000 11.63000 ? 23  LEU E CB  1 
ATOM   5565 C CG  . LEU E 2 23  ? -4.42800  27.18500  37.14400  1.000 13.94000 ? 23  LEU E CG  1 
ATOM   5566 C CD1 . LEU E 2 23  ? -4.55400  26.08400  38.18500  1.000 14.21000 ? 23  LEU E CD1 1 
ATOM   5567 C CD2 . LEU E 2 23  ? -4.67300  28.59400  37.74700  1.000 15.68000 ? 23  LEU E CD2 1 
ATOM   5568 N N   . ASN E 2 24  ? -4.68300  24.65800  34.67900  1.000 11.18000 ? 24  ASN E N   1 
ATOM   5569 C CA  . ASN E 2 24  ? -5.68600  24.28700  33.69600  1.000 14.59000 ? 24  ASN E CA  1 
ATOM   5570 C C   . ASN E 2 24  ? -7.07000  24.36800  34.30200  1.000 12.84000 ? 24  ASN E C   1 
ATOM   5571 O O   . ASN E 2 24  ? -7.28800  23.94200  35.43700  1.000 12.69000 ? 24  ASN E O   1 
ATOM   5572 C CB  . ASN E 2 24  ? -5.51300  22.84500  33.21300  1.000 10.22000 ? 24  ASN E CB  1 
ATOM   5573 C CG  . ASN E 2 24  ? -4.31300  22.67900  32.34700  1.000 11.55000 ? 24  ASN E CG  1 
ATOM   5574 O OD1 . ASN E 2 24  ? -3.89800  23.61600  31.66400  1.000 15.64000 ? 24  ASN E OD1 1 
ATOM   5575 N ND2 . ASN E 2 24  ? -3.73800  21.46600  32.35300  1.000 13.19000 ? 24  ASN E ND2 1 
ATOM   5576 N N   . CYS E 2 25  ? -8.04500  24.78500  33.49500  1.000 10.06000 ? 25  CYS E N   1 
ATOM   5577 C CA  . CYS E 2 25  ? -9.44300  24.63000  33.87000  1.000 9.03000  ? 25  CYS E CA  1 
ATOM   5578 C C   . CYS E 2 25  ? -10.11600 23.99700  32.65300  1.000 12.73000 ? 25  CYS E C   1 
ATOM   5579 O O   . CYS E 2 25  ? -10.17100 24.61500  31.59500  1.000 12.07000 ? 25  CYS E O   1 
ATOM   5580 C CB  . CYS E 2 25  ? -10.10600 25.97100  34.19700  1.000 12.97000 ? 25  CYS E CB  1 
ATOM   5581 S SG  . CYS E 2 25  ? -11.82800 25.72700  34.70100  1.000 16.58000 ? 25  CYS E SG  1 
ATOM   5582 N N   . TYR E 2 26  ? -10.57000 22.76800  32.79900  1.000 12.55000 ? 26  TYR E N   1 
ATOM   5583 C CA  . TYR E 2 26  ? -11.23900 21.99000  31.75300  1.000 8.67000  ? 26  TYR E CA  1 
ATOM   5584 C C   . TYR E 2 26  ? -12.75200 22.04700  32.00300  1.000 10.07000 ? 26  TYR E C   1 
ATOM   5585 O O   . TYR E 2 26  ? -13.24000 21.55100  33.03400  1.000 10.25000 ? 26  TYR E O   1 
ATOM   5586 C CB  . TYR E 2 26  ? -10.71800 20.55800  31.79200  1.000 11.13000 ? 26  TYR E CB  1 
ATOM   5587 C CG  . TYR E 2 26  ? -11.27000 19.70400  30.72800  1.000 9.92000  ? 26  TYR E CG  1 
ATOM   5588 C CD1 . TYR E 2 26  ? -11.09800 20.05100  29.38500  1.000 13.12000 ? 26  TYR E CD1 1 
ATOM   5589 C CD2 . TYR E 2 26  ? -11.94900 18.52700  31.02600  1.000 14.89000 ? 26  TYR E CD2 1 
ATOM   5590 C CE1 . TYR E 2 26  ? -11.62000 19.25700  28.35000  1.000 11.82000 ? 26  TYR E CE1 1 
ATOM   5591 C CE2 . TYR E 2 26  ? -12.49500 17.71400  29.99000  1.000 14.47000 ? 26  TYR E CE2 1 
ATOM   5592 C CZ  . TYR E 2 26  ? -12.29700 18.08700  28.67300  1.000 14.97000 ? 26  TYR E CZ  1 
ATOM   5593 O OH  . TYR E 2 26  ? -12.79900 17.31100  27.68100  1.000 17.80000 ? 26  TYR E OH  1 
ATOM   5594 N N   . VAL E 2 27  ? -13.50200 22.65300  31.08000  1.000 9.24000  ? 27  VAL E N   1 
ATOM   5595 C CA  . VAL E 2 27  ? -14.96500 22.68000  31.18500  1.000 9.33000  ? 27  VAL E CA  1 
ATOM   5596 C C   . VAL E 2 27  ? -15.55200 21.80600  30.08700  1.000 10.82000 ? 27  VAL E C   1 
ATOM   5597 O O   . VAL E 2 27  ? -15.07100 21.82500  28.96300  1.000 12.31000 ? 27  VAL E O   1 
ATOM   5598 C CB  . VAL E 2 27  ? -15.53200 24.11600  31.09400  1.000 14.43000 ? 27  VAL E CB  1 
ATOM   5599 C CG1 . VAL E 2 27  ? -15.19700 24.87900  32.35800  1.000 18.11000 ? 27  VAL E CG1 1 
ATOM   5600 C CG2 . VAL E 2 27  ? -14.97300 24.84400  29.86300  1.000 14.97000 ? 27  VAL E CG2 1 
ATOM   5601 N N   . SER E 2 28  ? -16.53400 20.97600  30.42300  1.000 10.07000 ? 28  SER E N   1 
ATOM   5602 C CA  . SER E 2 28  ? -16.99600 20.00400  29.44000  1.000 12.43000 ? 28  SER E CA  1 
ATOM   5603 C C   . SER E 2 28  ? -18.46200 19.67900  29.72100  1.000 12.99000 ? 28  SER E C   1 
ATOM   5604 O O   . SER E 2 28  ? -19.05500 20.11300  30.73200  1.000 15.01000 ? 28  SER E O   1 
ATOM   5605 C CB  . SER E 2 28  ? -16.13400 18.71700  29.47100  1.000 15.84000 ? 28  SER E CB  1 
ATOM   5606 O OG  . SER E 2 28  ? -16.21100 18.15500  30.80400  1.000 15.51000 ? 28  SER E OG  1 
ATOM   5607 N N   . GLY E 2 29  ? -19.06500 18.95700  28.79400  1.000 12.09000 ? 29  GLY E N   1 
ATOM   5608 C CA  . GLY E 2 29  ? -20.43800 18.53600  29.04100  1.000 12.61000 ? 29  GLY E CA  1 
ATOM   5609 C C   . GLY E 2 29  ? -21.46500 19.62400  29.00000  1.000 14.03000 ? 29  GLY E C   1 
ATOM   5610 O O   . GLY E 2 29  ? -22.59000 19.40800  29.46900  1.000 14.05000 ? 29  GLY E O   1 
ATOM   5611 N N   . PHE E 2 30  ? -21.15400 20.79100  28.42500  1.000 11.26000 ? 30  PHE E N   1 
ATOM   5612 C CA  . PHE E 2 30  ? -22.13000 21.86900  28.45300  1.000 11.04000 ? 30  PHE E CA  1 
ATOM   5613 C C   . PHE E 2 30  ? -22.76500 22.13200  27.08900  1.000 14.29000 ? 30  PHE E C   1 
ATOM   5614 O O   . PHE E 2 30  ? -22.23400 21.77000  26.02100  1.000 11.63000 ? 30  PHE E O   1 
ATOM   5615 C CB  . PHE E 2 30  ? -21.51700 23.17800  28.98800  1.000 10.95000 ? 30  PHE E CB  1 
ATOM   5616 C CG  . PHE E 2 30  ? -20.32000 23.66600  28.24300  1.000 14.74000 ? 30  PHE E CG  1 
ATOM   5617 C CD1 . PHE E 2 30  ? -19.00900 23.18000  28.57900  1.000 12.83000 ? 30  PHE E CD1 1 
ATOM   5618 C CD2 . PHE E 2 30  ? -20.43800 24.69500  27.30700  1.000 11.86000 ? 30  PHE E CD2 1 
ATOM   5619 C CE1 . PHE E 2 30  ? -17.86600 23.65200  27.88200  1.000 12.18000 ? 30  PHE E CE1 1 
ATOM   5620 C CE2 . PHE E 2 30  ? -19.24300 25.20700  26.63800  1.000 12.40000 ? 30  PHE E CE2 1 
ATOM   5621 C CZ  . PHE E 2 30  ? -17.98600 24.66500  26.94000  1.000 10.76000 ? 30  PHE E CZ  1 
ATOM   5622 N N   . HIS E 2 31  ? -23.96400 22.76300  27.14700  1.000 12.84000 ? 31  HIS E N   1 
ATOM   5623 C CA  . HIS E 2 31  ? -24.67100 23.19500  25.92400  1.000 12.77000 ? 31  HIS E CA  1 
ATOM   5624 C C   . HIS E 2 31  ? -25.62700 24.28300  26.37200  1.000 14.83000 ? 31  HIS E C   1 
ATOM   5625 O O   . HIS E 2 31  ? -26.26500 24.10400  27.42900  1.000 13.18000 ? 31  HIS E O   1 
ATOM   5626 C CB  . HIS E 2 31  ? -25.41900 22.00000  25.28900  1.000 14.34000 ? 31  HIS E CB  1 
ATOM   5627 C CG  . HIS E 2 31  ? -25.45700 22.03500  23.78100  1.000 18.96000 ? 31  HIS E CG  1 
ATOM   5628 N ND1 . HIS E 2 31  ? -26.21300 22.96000  23.07800  1.000 15.69000 ? 31  HIS E ND1 1 
ATOM   5629 C CD2 . HIS E 2 31  ? -24.83800 21.25600  22.84900  1.000 12.30000 ? 31  HIS E CD2 1 
ATOM   5630 C CE1 . HIS E 2 31  ? -26.05200 22.75000  21.77300  1.000 14.97000 ? 31  HIS E CE1 1 
ATOM   5631 N NE2 . HIS E 2 31  ? -25.21600 21.73100  21.61300  1.000 12.98000 ? 31  HIS E NE2 1 
ATOM   5632 N N   . PRO E 2 32  ? -25.75700 25.41800  25.66200  1.000 15.75000 ? 32  PRO E N   1 
ATOM   5633 C CA  . PRO E 2 32  ? -25.10600 25.86500  24.41900  1.000 14.07000 ? 32  PRO E CA  1 
ATOM   5634 C C   . PRO E 2 32  ? -23.63200 26.16900  24.64800  1.000 16.11000 ? 32  PRO E C   1 
ATOM   5635 O O   . PRO E 2 32  ? -23.18000 26.08200  25.81500  1.000 10.63000 ? 32  PRO E O   1 
ATOM   5636 C CB  . PRO E 2 32  ? -25.89500 27.12600  24.05300  1.000 18.82000 ? 32  PRO E CB  1 
ATOM   5637 C CG  . PRO E 2 32  ? -26.41500 27.65700  25.37100  1.000 17.97000 ? 32  PRO E CG  1 
ATOM   5638 C CD  . PRO E 2 32  ? -26.69900 26.43600  26.19000  1.000 18.45000 ? 32  PRO E CD  1 
ATOM   5639 N N   . SER E 2 33  ? -22.88800 26.60000  23.61400  1.000 13.28000 ? 33  SER E N   1 
ATOM   5640 C CA  . SER E 2 33  ? -21.43400 26.73800  23.72700  1.000 12.60000 ? 33  SER E CA  1 
ATOM   5641 C C   . SER E 2 33  ? -20.96300 28.06000  24.35400  1.000 13.48000 ? 33  SER E C   1 
ATOM   5642 O O   . SER E 2 33  ? -19.81000 28.12000  24.80700  1.000 15.58000 ? 33  SER E O   1 
ATOM   5643 C CB  . SER E 2 33  ? -20.76800 26.59800  22.32000  1.000 14.84000 ? 33  SER E CB  1 
ATOM   5644 O OG  . SER E 2 33  ? -21.29500 27.62400  21.48000  1.000 14.87000 ? 33  SER E OG  1 
ATOM   5645 N N   . ASP E 2 34  ? -21.76100 29.12400  24.36900  1.000 16.06000 ? 34  ASP E N   1 
ATOM   5646 C CA  . ASP E 2 34  ? -21.28900 30.33600  25.06900  1.000 17.93000 ? 34  ASP E CA  1 
ATOM   5647 C C   . ASP E 2 34  ? -20.96700 30.03600  26.51900  1.000 12.91000 ? 34  ASP E C   1 
ATOM   5648 O O   . ASP E 2 34  ? -21.78800 29.51600  27.25500  1.000 13.53000 ? 34  ASP E O   1 
ATOM   5649 C CB  . ASP E 2 34  ? -22.30200 31.47500  25.04600  1.000 18.00000 ? 34  ASP E CB  1 
ATOM   5650 C CG  . ASP E 2 34  ? -22.37500 32.16400  23.68200  1.000 39.04000 ? 34  ASP E CG  1 
ATOM   5651 O OD1 . ASP E 2 34  ? -21.38600 32.13200  22.89800  1.000 48.28000 ? 34  ASP E OD1 1 
ATOM   5652 O OD2 . ASP E 2 34  ? -23.47300 32.68500  23.37000  1.000 57.83000 ? 34  ASP E OD2 1 
ATOM   5653 N N   . ILE E 2 35  ? -19.79000 30.46000  26.96800  1.000 14.49000 ? 35  ILE E N   1 
ATOM   5654 C CA  . ILE E 2 35  ? -19.37700 30.17800  28.33900  1.000 13.25000 ? 35  ILE E CA  1 
ATOM   5655 C C   . ILE E 2 35  ? -18.30100 31.19600  28.67200  1.000 17.47000 ? 35  ILE E C   1 
ATOM   5656 O O   . ILE E 2 35  ? -17.59600 31.67100  27.78400  1.000 18.80000 ? 35  ILE E O   1 
ATOM   5657 C CB  . ILE E 2 35  ? -18.86800 28.72300  28.46200  1.000 16.07000 ? 35  ILE E CB  1 
ATOM   5658 C CG1 . ILE E 2 35  ? -18.67600 28.28500  29.90100  1.000 14.12000 ? 35  ILE E CG1 1 
ATOM   5659 C CG2 . ILE E 2 35  ? -17.54600 28.53600  27.70100  1.000 11.29000 ? 35  ILE E CG2 1 
ATOM   5660 C CD1 . ILE E 2 35  ? -18.73700 26.73200  30.01700  1.000 14.39000 ? 35  ILE E CD1 1 
ATOM   5661 N N   . GLU E 2 36  ? -18.21000 31.56900  29.94300  1.000 15.14000 ? 36  GLU E N   1 
ATOM   5662 C CA  . GLU E 2 36  ? -17.19500 32.51200  30.40100  1.000 14.40000 ? 36  GLU E CA  1 
ATOM   5663 C C   . GLU E 2 36  ? -16.31500 31.80300  31.43300  1.000 16.83000 ? 36  GLU E C   1 
ATOM   5664 O O   . GLU E 2 36  ? -16.83200 31.21900  32.39600  1.000 17.69000 ? 36  GLU E O   1 
ATOM   5665 C CB  . GLU E 2 36  ? -17.85500 33.73400  31.05300  1.000 18.59000 ? 36  GLU E CB  1 
ATOM   5666 C CG  . GLU E 2 36  ? -16.81200 34.85700  31.32100  1.000 29.39000 ? 36  GLU E CG  1 
ATOM   5667 C CD  . GLU E 2 36  ? -17.43300 36.17900  31.84000  1.000 36.10000 ? 36  GLU E CD  1 
ATOM   5668 O OE1 . GLU E 2 36  ? -18.67500 36.30400  31.83100  1.000 40.99000 ? 36  GLU E OE1 1 
ATOM   5669 O OE2 . GLU E 2 36  ? -16.65500 37.10400  32.19100  1.000 41.08000 ? 36  GLU E OE2 1 
ATOM   5670 N N   . VAL E 2 37  ? -15.00100 31.79200  31.23100  1.000 16.13000 ? 37  VAL E N   1 
ATOM   5671 C CA  . VAL E 2 37  ? -14.15100 31.09000  32.19400  1.000 14.16000 ? 37  VAL E CA  1 
ATOM   5672 C C   . VAL E 2 37  ? -13.02500 32.04200  32.55700  1.000 14.58000 ? 37  VAL E C   1 
ATOM   5673 O O   . VAL E 2 37  ? -12.37300 32.58100  31.67500  1.000 18.13000 ? 37  VAL E O   1 
ATOM   5674 C CB  . VAL E 2 37  ? -13.60200 29.76500  31.62700  1.000 14.56000 ? 37  VAL E CB  1 
ATOM   5675 C CG1 . VAL E 2 37  ? -12.70700 29.07700  32.64600  1.000 16.67000 ? 37  VAL E CG1 1 
ATOM   5676 C CG2 . VAL E 2 37  ? -14.76900 28.83800  31.29200  1.000 10.58000 ? 37  VAL E CG2 1 
ATOM   5677 N N   . ASP E 2 38  ? -12.81000 32.25700  33.83200  1.000 14.95000 ? 38  ASP E N   1 
ATOM   5678 C CA  . ASP E 2 38  ? -11.67800 33.02700  34.32400  1.000 15.55000 ? 38  ASP E CA  1 
ATOM   5679 C C   . ASP E 2 38  ? -10.83300 32.13200  35.21000  1.000 16.88000 ? 38  ASP E C   1 
ATOM   5680 O O   . ASP E 2 38  ? -11.38500 31.31700  35.96400  1.000 18.19000 ? 38  ASP E O   1 
ATOM   5681 C CB  . ASP E 2 38  ? -12.15800 34.19600  35.17300  1.000 17.47000 ? 38  ASP E CB  1 
ATOM   5682 C CG  . ASP E 2 38  ? -12.93700 35.20600  34.37100  1.000 26.92000 ? 38  ASP E CG  1 
ATOM   5683 O OD1 . ASP E 2 38  ? -12.45100 35.61200  33.29600  1.000 22.78000 ? 38  ASP E OD1 1 
ATOM   5684 O OD2 . ASP E 2 38  ? -14.00400 35.58500  34.83300  1.000 30.04000 ? 38  ASP E OD2 1 
ATOM   5685 N N   . LEU E 2 39  ? -9.51500  32.32200  35.18000  1.000 17.23000 ? 39  LEU E N   1 
ATOM   5686 C CA  . LEU E 2 39  ? -8.66800  31.74600  36.21800  1.000 12.06000 ? 39  LEU E CA  1 
ATOM   5687 C C   . LEU E 2 39  ? -8.36400  32.85000  37.24000  1.000 14.52000 ? 39  LEU E C   1 
ATOM   5688 O O   . LEU E 2 39  ? -8.05300  33.97400  36.85400  1.000 18.17000 ? 39  LEU E O   1 
ATOM   5689 C CB  . LEU E 2 39  ? -7.37700  31.19100  35.61600  1.000 13.30000 ? 39  LEU E CB  1 
ATOM   5690 C CG  . LEU E 2 39  ? -7.63100  30.15100  34.50400  1.000 18.30000 ? 39  LEU E CG  1 
ATOM   5691 C CD1 . LEU E 2 39  ? -6.28300  29.53400  33.93100  1.000 13.57000 ? 39  LEU E CD1 1 
ATOM   5692 C CD2 . LEU E 2 39  ? -8.50600  29.05600  35.04800  1.000 22.33000 ? 39  LEU E CD2 1 
ATOM   5693 N N   . LEU E 2 40  ? -8.41200  32.53400  38.53400  1.000 17.28000 ? 40  LEU E N   1 
ATOM   5694 C CA  . LEU E 2 40  ? -8.17600  33.56200  39.55000  1.000 13.24000 ? 40  LEU E CA  1 
ATOM   5695 C C   . LEU E 2 40  ? -6.93300  33.22100  40.34900  1.000 18.45000 ? 40  LEU E C   1 
ATOM   5696 O O   . LEU E 2 40  ? -6.69000  32.04500  40.65400  1.000 15.68000 ? 40  LEU E O   1 
ATOM   5697 C CB  . LEU E 2 40  ? -9.34600  33.67200  40.50500  1.000 16.71000 ? 40  LEU E CB  1 
ATOM   5698 C CG  . LEU E 2 40  ? -10.75900 33.69900  39.91300  1.000 19.32000 ? 40  LEU E CG  1 
ATOM   5699 C CD1 . LEU E 2 40  ? -11.80200 33.69400  41.00800  1.000 15.28000 ? 40  LEU E CD1 1 
ATOM   5700 C CD2 . LEU E 2 40  ? -10.88200 34.90500  39.08100  1.000 20.17000 ? 40  LEU E CD2 1 
ATOM   5701 N N   . LYS E 2 41  ? -6.20500  34.26700  40.76700  1.000 19.08000 ? 41  LYS E N   1 
ATOM   5702 C CA  . LYS E 2 41  ? -5.11600  34.12800  41.73800  1.000 17.28000 ? 41  LYS E CA  1 
ATOM   5703 C C   . LYS E 2 41  ? -5.47100  34.95400  42.97000  1.000 22.92000 ? 41  LYS E C   1 
ATOM   5704 O O   . LYS E 2 41  ? -5.67200  36.15700  42.86400  1.000 23.56000 ? 41  LYS E O   1 
ATOM   5705 C CB  . LYS E 2 41  ? -3.79300  34.62100  41.13400  1.000 17.38000 ? 41  LYS E CB  1 
ATOM   5706 C CG  . LYS E 2 41  ? -2.57000  34.62100  42.15300  1.000 18.85000 ? 41  LYS E CG  1 
ATOM   5707 C CD  . LYS E 2 41  ? -1.25200  35.05600  41.46500  1.000 18.72000 ? 41  LYS E CD  1 
ATOM   5708 C CE  . LYS E 2 41  ? -0.06500  34.97100  42.45300  1.000 28.86000 ? 41  LYS E CE  1 
ATOM   5709 N NZ  . LYS E 2 41  ? 1.13900   35.63800  41.82400  1.000 29.71000 ? 41  LYS E NZ  1 
ATOM   5710 N N   . ASN E 2 42  ? -5.56700  34.31500  44.12300  1.000 23.37000 ? 42  ASN E N   1 
ATOM   5711 C CA  . ASN E 2 42  ? -6.03300  34.99900  45.31500  1.000 26.18000 ? 42  ASN E CA  1 
ATOM   5712 C C   . ASN E 2 42  ? -7.28700  35.81700  45.02200  1.000 29.55000 ? 42  ASN E C   1 
ATOM   5713 O O   . ASN E 2 42  ? -7.40700  36.98200  45.40400  1.000 29.55000 ? 42  ASN E O   1 
ATOM   5714 C CB  . ASN E 2 42  ? -4.89800  35.84300  45.88900  1.000 28.38000 ? 42  ASN E CB  1 
ATOM   5715 C CG  . ASN E 2 42  ? -3.72800  34.96000  46.28700  1.000 24.90000 ? 42  ASN E CG  1 
ATOM   5716 O OD1 . ASN E 2 42  ? -3.93400  33.94400  46.95600  1.000 27.14000 ? 42  ASN E OD1 1 
ATOM   5717 N ND2 . ASN E 2 42  ? -2.52500  35.28100  45.80800  1.000 24.46000 ? 42  ASN E ND2 1 
ATOM   5718 N N   . GLY E 2 43  ? -8.22200  35.20300  44.30100  1.000 21.51000 ? 43  GLY E N   1 
ATOM   5719 C CA  . GLY E 2 43  ? -9.47700  35.85000  43.97300  1.000 23.78000 ? 43  GLY E CA  1 
ATOM   5720 C C   . GLY E 2 43  ? -9.46800  36.88400  42.84700  1.000 25.36000 ? 43  GLY E C   1 
ATOM   5721 O O   . GLY E 2 43  ? -10.54100 37.36900  42.47600  1.000 28.27000 ? 43  GLY E O   1 
ATOM   5722 N N   . GLU E 2 44  ? -8.33000  37.26400  42.30400  1.000 24.68000 ? 44  GLU E N   1 
ATOM   5723 C CA  . GLU E 2 44  ? -8.27600  38.24000  41.21700  1.000 26.98000 ? 44  GLU E CA  1 
ATOM   5724 C C   . GLU E 2 44  ? -8.08400  37.55400  39.87300  1.000 23.03000 ? 44  GLU E C   1 
ATOM   5725 O O   . GLU E 2 44  ? -7.31900  36.58400  39.76100  1.000 19.71000 ? 44  GLU E O   1 
ATOM   5726 C CB  . GLU E 2 44  ? -7.13100  39.23800  41.44100  1.000 30.12000 ? 44  GLU E CB  1 
ATOM   5727 C CG  . GLU E 2 44  ? -7.29600  40.13500  42.67000  1.000 36.51000 ? 44  GLU E CG  1 
ATOM   5728 C CD  . GLU E 2 44  ? -8.63600  40.92400  42.64200  1.000 56.36000 ? 44  GLU E CD  1 
ATOM   5729 O OE1 . GLU E 2 44  ? -8.83700  41.77900  41.72600  1.000 55.63000 ? 44  GLU E OE1 1 
ATOM   5730 O OE2 . GLU E 2 44  ? -9.48400  40.70800  43.54000  1.000 52.60000 ? 44  GLU E OE2 1 
ATOM   5731 N N   . ARG E 2 45  ? -8.75600  38.08000  38.85600  1.000 21.72000 ? 45  ARG E N   1 
ATOM   5732 C CA  . ARG E 2 45  ? -8.70800  37.46900  37.52700  1.000 22.62000 ? 45  ARG E CA  1 
ATOM   5733 C C   . ARG E 2 45  ? -7.30200  37.54100  36.93800  1.000 26.58000 ? 45  ARG E C   1 
ATOM   5734 O O   . ARG E 2 45  ? -6.67500  38.60700  36.95600  1.000 21.57000 ? 45  ARG E O   1 
ATOM   5735 C CB  . ARG E 2 45  ? -9.68900  38.18300  36.61600  1.000 27.62000 ? 45  ARG E CB  1 
ATOM   5736 C CG  . ARG E 2 45  ? -9.56600  37.81700  35.16000  1.000 28.64000 ? 45  ARG E CG  1 
ATOM   5737 C CD  . ARG E 2 45  ? -10.72200 38.39700  34.31300  1.000 23.53000 ? 45  ARG E CD  1 
ATOM   5738 N NE  . ARG E 2 45  ? -10.65800 37.76800  32.99600  1.000 35.14000 ? 45  ARG E NE  1 
ATOM   5739 C CZ  . ARG E 2 45  ? -9.85000  38.16800  32.02800  1.000 37.36000 ? 45  ARG E CZ  1 
ATOM   5740 N NH1 . ARG E 2 45  ? -9.19000  39.31000  32.12300  1.000 38.99000 ? 45  ARG E NH1 1 
ATOM   5741 N NH2 . ARG E 2 45  ? -9.72600  37.42100  30.93200  1.000 34.23000 ? 45  ARG E NH2 1 
ATOM   5742 N N   . ILE E 2 46  ? -6.80200  36.39700  36.42000  1.000 18.77000 ? 46  ILE E N   1 
ATOM   5743 C CA  . ILE E 2 46  ? -5.50600  36.31300  35.75300  1.000 19.56000 ? 46  ILE E CA  1 
ATOM   5744 C C   . ILE E 2 46  ? -5.68500  36.76500  34.31100  1.000 23.42000 ? 46  ILE E C   1 
ATOM   5745 O O   . ILE E 2 46  ? -6.60400  36.32400  33.63200  1.000 20.51000 ? 46  ILE E O   1 
ATOM   5746 C CB  . ILE E 2 46  ? -4.94900  34.87400  35.83600  1.000 19.02000 ? 46  ILE E CB  1 
ATOM   5747 C CG1 . ILE E 2 46  ? -4.72900  34.44800  37.27800  1.000 18.76000 ? 46  ILE E CG1 1 
ATOM   5748 C CG2 . ILE E 2 46  ? -3.67700  34.71100  35.05700  1.000 17.41000 ? 46  ILE E CG2 1 
ATOM   5749 C CD1 . ILE E 2 46  ? -4.36900  32.95600  37.45800  1.000 16.73000 ? 46  ILE E CD1 1 
ATOM   5750 N N   . GLU E 2 47  ? -4.84900  37.68000  33.84200  1.000 21.04000 ? 47  GLU E N   1 
ATOM   5751 C CA  . GLU E 2 47  ? -5.08700  38.27000  32.51200  1.000 28.87000 ? 47  GLU E CA  1 
ATOM   5752 C C   . GLU E 2 47  ? -4.61900  37.38800  31.34700  1.000 25.02000 ? 47  GLU E C   1 
ATOM   5753 O O   . GLU E 2 47  ? -5.28300  37.31200  30.31700  1.000 29.36000 ? 47  GLU E O   1 
ATOM   5754 C CB  . GLU E 2 47  ? -4.35600  39.60400  32.41100  1.000 30.79000 ? 47  GLU E CB  1 
ATOM   5755 C CG  . GLU E 2 47  ? -4.98800  40.61600  33.28300  1.000 39.59000 ? 47  GLU E CG  1 
ATOM   5756 C CD  . GLU E 2 47  ? -6.33500  41.08200  32.76700  1.000 40.32000 ? 47  GLU E CD  1 
ATOM   5757 O OE1 . GLU E 2 47  ? -6.56500  41.06500  31.53700  1.000 35.20000 ? 47  GLU E OE1 1 
ATOM   5758 O OE2 . GLU E 2 47  ? -7.14900  41.44700  33.63700  1.000 44.64000 ? 47  GLU E OE2 1 
ATOM   5759 N N   . LYS E 2 48  ? -3.44000  36.79600  31.43500  1.000 24.72000 ? 48  LYS E N   1 
ATOM   5760 C CA  . LYS E 2 48  ? -2.86900  36.02800  30.30800  1.000 21.36000 ? 48  LYS E CA  1 
ATOM   5761 C C   . LYS E 2 48  ? -3.32900  34.58400  30.41600  1.000 24.10000 ? 48  LYS E C   1 
ATOM   5762 O O   . LYS E 2 48  ? -2.62900  33.71500  30.95300  1.000 26.71000 ? 48  LYS E O   1 
ATOM   5763 C CB  . LYS E 2 48  ? -1.33700  36.09000  30.30900  1.000 22.77000 ? 48  LYS E CB  1 
ATOM   5764 C CG  . LYS E 2 48  ? -0.68700  36.15400  28.93900  1.000 28.37000 ? 48  LYS E CG  1 
ATOM   5765 C CD  . LYS E 2 48  ? 0.44600   35.14100  28.83100  0.000 28.50000 ? 48  LYS E CD  1 
ATOM   5766 C CE  . LYS E 2 48  ? 1.14100   35.21700  27.48100  0.000 30.68000 ? 48  LYS E CE  1 
ATOM   5767 N NZ  . LYS E 2 48  ? 0.18900   35.01700  26.35600  0.000 32.58000 ? 48  LYS E NZ  1 
ATOM   5768 N N   . VAL E 2 49  ? -4.52100  34.32200  29.89500  1.000 22.56000 ? 49  VAL E N   1 
ATOM   5769 C CA  . VAL E 2 49  ? -5.15000  32.99200  29.91900  1.000 15.17000 ? 49  VAL E CA  1 
ATOM   5770 C C   . VAL E 2 49  ? -5.48900  32.64900  28.47800  1.000 19.08000 ? 49  VAL E C   1 
ATOM   5771 O O   . VAL E 2 49  ? -6.13900  33.44100  27.79300  1.000 22.07000 ? 49  VAL E O   1 
ATOM   5772 C CB  . VAL E 2 49  ? -6.43800  32.98800  30.76300  1.000 15.76000 ? 49  VAL E CB  1 
ATOM   5773 C CG1 . VAL E 2 49  ? -7.18800  31.68800  30.65200  1.000 19.92000 ? 49  VAL E CG1 1 
ATOM   5774 C CG2 . VAL E 2 49  ? -6.11800  33.22600  32.27400  1.000 18.02000 ? 49  VAL E CG2 1 
ATOM   5775 N N   . GLU E 2 50  ? -5.08500  31.48900  28.01900  1.000 16.93000 ? 50  GLU E N   1 
ATOM   5776 C CA  . GLU E 2 50  ? -5.47800  31.07200  26.68300  1.000 17.15000 ? 50  GLU E CA  1 
ATOM   5777 C C   . GLU E 2 50  ? -6.47400  29.92500  26.76500  1.000 15.51000 ? 50  GLU E C   1 
ATOM   5778 O O   . GLU E 2 50  ? -6.73500  29.37800  27.84700  1.000 13.67000 ? 50  GLU E O   1 
ATOM   5779 C CB  . GLU E 2 50  ? -4.24900  30.66600  25.86000  1.000 23.07000 ? 50  GLU E CB  1 
ATOM   5780 C CG  . GLU E 2 50  ? -3.32800  31.86200  25.53400  1.000 29.10000 ? 50  GLU E CG  1 
ATOM   5781 C CD  . GLU E 2 50  ? -1.98300  31.41100  25.07400  1.000 43.25000 ? 50  GLU E CD  1 
ATOM   5782 O OE1 . GLU E 2 50  ? -1.07700  31.19900  25.92100  1.000 47.96000 ? 50  GLU E OE1 1 
ATOM   5783 O OE2 . GLU E 2 50  ? -1.85900  31.23400  23.83400  1.000 55.68000 ? 50  GLU E OE2 1 
ATOM   5784 N N   . HIS E 2 51  ? -7.08700  29.58000  25.61200  1.000 15.99000 ? 51  HIS E N   1 
ATOM   5785 C CA  . HIS E 2 51  ? -8.03800  28.47100  25.61200  1.000 11.53000 ? 51  HIS E CA  1 
ATOM   5786 C C   . HIS E 2 51  ? -7.96100  27.72200  24.28700  1.000 15.51000 ? 51  HIS E C   1 
ATOM   5787 O O   . HIS E 2 51  ? -7.56200  28.28200  23.24200  1.000 13.04000 ? 51  HIS E O   1 
ATOM   5788 C CB  . HIS E 2 51  ? -9.47900  28.92000  25.86600  1.000 11.07000 ? 51  HIS E CB  1 
ATOM   5789 C CG  . HIS E 2 51  ? -10.00600 29.87600  24.83600  1.000 18.81000 ? 51  HIS E CG  1 
ATOM   5790 N ND1 . HIS E 2 51  ? -10.46100 29.46500  23.59800  1.000 23.38000 ? 51  HIS E ND1 1 
ATOM   5791 C CD2 . HIS E 2 51  ? -10.17100 31.22500  24.87300  1.000 20.94000 ? 51  HIS E CD2 1 
ATOM   5792 C CE1 . HIS E 2 51  ? -10.85100 30.53100  22.90500  1.000 29.46000 ? 51  HIS E CE1 1 
ATOM   5793 N NE2 . HIS E 2 51  ? -10.66700 31.60900  23.65200  1.000 27.96000 ? 51  HIS E NE2 1 
ATOM   5794 N N   . SER E 2 52  ? -8.41500  26.47600  24.34400  1.000 12.25000 ? 52  SER E N   1 
ATOM   5795 C CA  . SER E 2 52  ? -8.39600  25.58300  23.19000  1.000 14.36000 ? 52  SER E CA  1 
ATOM   5796 C C   . SER E 2 52  ? -9.50500  26.01200  22.20400  1.000 17.33000 ? 52  SER E C   1 
ATOM   5797 O O   . SER E 2 52  ? -10.30600 26.90800  22.48500  1.000 14.76000 ? 52  SER E O   1 
ATOM   5798 C CB  . SER E 2 52  ? -8.61700  24.14400  23.65700  1.000 16.03000 ? 52  SER E CB  1 
ATOM   5799 O OG  . SER E 2 52  ? -9.90100  24.06100  24.29900  1.000 14.99000 ? 52  SER E OG  1 
ATOM   5800 N N   . ASP E 2 53  ? -9.49500  25.41800  21.00100  1.000 13.73000 ? 53  ASP E N   1 
ATOM   5801 C CA  . ASP E 2 53  ? -10.51100 25.71000  20.01200  1.000 14.11000 ? 53  ASP E CA  1 
ATOM   5802 C C   . ASP E 2 53  ? -11.76500 24.88600  20.29900  1.000 16.17000 ? 53  ASP E C   1 
ATOM   5803 O O   . ASP E 2 53  ? -11.66600 23.71700  20.67800  1.000 13.83000 ? 53  ASP E O   1 
ATOM   5804 C CB  . ASP E 2 53  ? -10.00900 25.38100  18.59400  1.000 10.56000 ? 53  ASP E CB  1 
ATOM   5805 C CG  . ASP E 2 53  ? -8.69000  26.01400  18.28900  1.000 17.73000 ? 53  ASP E CG  1 
ATOM   5806 O OD1 . ASP E 2 53  ? -8.54600  27.25600  18.56500  1.000 17.46000 ? 53  ASP E OD1 1 
ATOM   5807 O OD2 . ASP E 2 53  ? -7.77900  25.27000  17.81300  1.000 14.37000 ? 53  ASP E OD2 1 
ATOM   5808 N N   . LEU E 2 54  ? -12.92900 25.48800  20.04000  1.000 12.40000 ? 54  LEU E N   1 
ATOM   5809 C CA  . LEU E 2 54  ? -14.19600 24.86900  20.41800  1.000 12.74000 ? 54  LEU E CA  1 
ATOM   5810 C C   . LEU E 2 54  ? -14.36600 23.53200  19.73200  1.000 10.42000 ? 54  LEU E C   1 
ATOM   5811 O O   . LEU E 2 54  ? -14.23300 23.42100  18.49800  1.000 11.25000 ? 54  LEU E O   1 
ATOM   5812 C CB  . LEU E 2 54  ? -15.34300 25.78900  20.04300  1.000 11.78000 ? 54  LEU E CB  1 
ATOM   5813 C CG  . LEU E 2 54  ? -16.74700 25.39100  20.57000  1.000 9.64000  ? 54  LEU E CG  1 
ATOM   5814 C CD1 . LEU E 2 54  ? -16.81200 25.31000  22.14800  1.000 12.36000 ? 54  LEU E CD1 1 
ATOM   5815 C CD2 . LEU E 2 54  ? -17.88000 26.32800  19.99100  1.000 11.78000 ? 54  LEU E CD2 1 
ATOM   5816 N N   . SER E 2 55  ? -14.71700 22.51800  20.51800  1.000 11.78000 ? 55  SER E N   1 
ATOM   5817 C CA  . SER E 2 55  ? -14.93700 21.16700  20.00000  1.000 10.80000 ? 55  SER E CA  1 
ATOM   5818 C C   . SER E 2 55  ? -16.00500 20.50800  20.85800  1.000 11.03000 ? 55  SER E C   1 
ATOM   5819 O O   . SER E 2 55  ? -16.52300 21.11800  21.78400  1.000 10.90000 ? 55  SER E O   1 
ATOM   5820 C CB  . SER E 2 55  ? -13.65600 20.31800  20.02200  1.000 14.59000 ? 55  SER E CB  1 
ATOM   5821 O OG  . SER E 2 55  ? -13.94300 19.18300  19.21600  1.000 16.37000 ? 55  SER E OG  1 
ATOM   5822 N N   . PHE E 2 56  ? -16.39600 19.29200  20.51300  1.000 11.19000 ? 56  PHE E N   1 
ATOM   5823 C CA  . PHE E 2 56  ? -17.49600 18.68700  21.25000  1.000 10.00000 ? 56  PHE E CA  1 
ATOM   5824 C C   . PHE E 2 56  ? -17.34400 17.16500  21.19500  1.000 15.57000 ? 56  PHE E C   1 
ATOM   5825 O O   . PHE E 2 56  ? -16.64600 16.61900  20.33100  1.000 12.51000 ? 56  PHE E O   1 
ATOM   5826 C CB  . PHE E 2 56  ? -18.88900 19.14400  20.74000  1.000 7.14000  ? 56  PHE E CB  1 
ATOM   5827 C CG  . PHE E 2 56  ? -19.10700 18.95900  19.22500  1.000 11.85000 ? 56  PHE E CG  1 
ATOM   5828 C CD1 . PHE E 2 56  ? -19.55600 17.75900  18.72500  1.000 11.68000 ? 56  PHE E CD1 1 
ATOM   5829 C CD2 . PHE E 2 56  ? -18.89800 20.01900  18.33000  1.000 8.43000  ? 56  PHE E CD2 1 
ATOM   5830 C CE1 . PHE E 2 56  ? -19.78000 17.56500  17.38300  1.000 9.89000  ? 56  PHE E CE1 1 
ATOM   5831 C CE2 . PHE E 2 56  ? -19.15400 19.85200  16.93000  1.000 10.43000 ? 56  PHE E CE2 1 
ATOM   5832 C CZ  . PHE E 2 56  ? -19.58400 18.60400  16.45300  1.000 8.43000  ? 56  PHE E CZ  1 
ATOM   5833 N N   . SER E 2 57  ? -18.06200 16.50200  22.10800  1.000 11.92000 ? 57  SER E N   1 
ATOM   5834 C CA  . SER E 2 57  ? -18.02800 15.06400  22.30700  1.000 15.81000 ? 57  SER E CA  1 
ATOM   5835 C C   . SER E 2 57  ? -19.14400 14.37200  21.53300  1.000 17.04000 ? 57  SER E C   1 
ATOM   5836 O O   . SER E 2 57  ? -19.98500 15.01400  20.91700  1.000 12.75000 ? 57  SER E O   1 
ATOM   5837 C CB  . SER E 2 57  ? -18.20800 14.73900  23.78700  1.000 20.25000 ? 57  SER E CB  1 
ATOM   5838 O OG  . SER E 2 57  ? -17.40300 15.60900  24.56100  1.000 21.11000 ? 57  SER E OG  1 
ATOM   5839 N N   . GLY E 2 58  ? -19.15700 13.02700  21.58800  1.000 16.86000 ? 58  GLY E N   1 
ATOM   5840 C CA  . GLY E 2 58  ? -20.12300 12.27200  20.79400  1.000 16.60000 ? 58  GLY E CA  1 
ATOM   5841 C C   . GLY E 2 58  ? -21.55400 12.61000  21.16300  1.000 14.12000 ? 58  GLY E C   1 
ATOM   5842 O O   . GLY E 2 58  ? -22.45600 12.51200  20.32100  1.000 18.22000 ? 58  GLY E O   1 
ATOM   5843 N N   . ASP E 2 59  ? -21.79200 13.06700  22.39300  1.000 15.55000 ? 59  ASP E N   1 
ATOM   5844 C CA  . ASP E 2 59  ? -23.17200 13.42000  22.81100  1.000 13.00000 ? 59  ASP E CA  1 
ATOM   5845 C C   . ASP E 2 59  ? -23.53200 14.87300  22.48900  1.000 15.63000 ? 59  ASP E C   1 
ATOM   5846 O O   . ASP E 2 59  ? -24.59200 15.35800  22.93500  1.000 16.48000 ? 59  ASP E O   1 
ATOM   5847 C CB  . ASP E 2 59  ? -23.39500 13.14800  24.29100  1.000 14.87000 ? 59  ASP E CB  1 
ATOM   5848 C CG  . ASP E 2 59  ? -22.59700 14.07600  25.20700  1.000 20.49000 ? 59  ASP E CG  1 
ATOM   5849 O OD1 . ASP E 2 59  ? -21.88800 15.00300  24.73300  1.000 17.18000 ? 59  ASP E OD1 1 
ATOM   5850 O OD2 . ASP E 2 59  ? -22.68000 13.89300  26.45000  1.000 23.38000 ? 59  ASP E OD2 1 
ATOM   5851 N N   . TRP E 2 60  ? -22.68500 15.55500  21.70500  1.000 12.86000 ? 60  TRP E N   1 
ATOM   5852 C CA  . TRP E 2 60  ? -22.83600 16.93400  21.21600  1.000 13.04000 ? 60  TRP E CA  1 
ATOM   5853 C C   . TRP E 2 60  ? -22.45300 17.98800  22.28200  1.000 11.23000 ? 60  TRP E C   1 
ATOM   5854 O O   . TRP E 2 60  ? -22.47700 19.21700  21.96200  1.000 10.85000 ? 60  TRP E O   1 
ATOM   5855 C CB  . TRP E 2 60  ? -24.26300 17.25800  20.68500  1.000 11.47000 ? 60  TRP E CB  1 
ATOM   5856 C CG  . TRP E 2 60  ? -24.68600 16.27700  19.64200  1.000 15.12000 ? 60  TRP E CG  1 
ATOM   5857 C CD1 . TRP E 2 60  ? -25.65400 15.28700  19.75300  1.000 14.82000 ? 60  TRP E CD1 1 
ATOM   5858 C CD2 . TRP E 2 60  ? -24.13300 16.15300  18.31400  1.000 14.50000 ? 60  TRP E CD2 1 
ATOM   5859 N NE1 . TRP E 2 60  ? -25.76400 14.59100  18.55900  1.000 11.89000 ? 60  TRP E NE1 1 
ATOM   5860 C CE2 . TRP E 2 60  ? -24.82400 15.07600  17.67000  1.000 13.88000 ? 60  TRP E CE2 1 
ATOM   5861 C CE3 . TRP E 2 60  ? -23.16900 16.90000  17.58600  1.000 9.32000  ? 60  TRP E CE3 1 
ATOM   5862 C CZ2 . TRP E 2 60  ? -24.58200 14.71200  16.31100  1.000 9.59000  ? 60  TRP E CZ2 1 
ATOM   5863 C CZ3 . TRP E 2 60  ? -22.90300 16.53200  16.27100  1.000 12.28000 ? 60  TRP E CZ3 1 
ATOM   5864 C CH2 . TRP E 2 60  ? -23.64900 15.46800  15.62800  1.000 13.17000 ? 60  TRP E CH2 1 
ATOM   5865 N N   . SER E 2 61  ? -22.07300 17.58900  23.50700  1.000 11.59000 ? 61  SER E N   1 
ATOM   5866 C CA  . SER E 2 61  ? -21.77300 18.62500  24.48400  1.000 11.59000 ? 61  SER E CA  1 
ATOM   5867 C C   . SER E 2 61  ? -20.35600 19.14900  24.25200  1.000 9.87000  ? 61  SER E C   1 
ATOM   5868 O O   . SER E 2 61  ? -19.48100 18.44000  23.78300  1.000 11.48000 ? 61  SER E O   1 
ATOM   5869 C CB  . SER E 2 61  ? -21.96200 18.10500  25.93500  1.000 13.55000 ? 61  SER E CB  1 
ATOM   5870 O OG  . SER E 2 61  ? -20.99200 17.05500  26.17000  1.000 17.68000 ? 61  SER E OG  1 
ATOM   5871 N N   . PHE E 2 62  ? -20.15700 20.42300  24.56000  1.000 12.15000 ? 62  PHE E N   1 
ATOM   5872 C CA  . PHE E 2 62  ? -18.92200 21.11200  24.18400  1.000 8.12000  ? 62  PHE E CA  1 
ATOM   5873 C C   . PHE E 2 62  ? -17.86100 20.92300  25.25300  1.000 11.80000 ? 62  PHE E C   1 
ATOM   5874 O O   . PHE E 2 62  ? -18.18000 20.66500  26.40600  1.000 11.40000 ? 62  PHE E O   1 
ATOM   5875 C CB  . PHE E 2 62  ? -19.22300 22.60100  24.03100  1.000 9.03000  ? 62  PHE E CB  1 
ATOM   5876 C CG  . PHE E 2 62  ? -20.10900 22.89800  22.84900  1.000 8.97000  ? 62  PHE E CG  1 
ATOM   5877 C CD1 . PHE E 2 62  ? -19.54800 22.91600  21.56700  1.000 7.82000  ? 62  PHE E CD1 1 
ATOM   5878 C CD2 . PHE E 2 62  ? -21.47600 23.13100  23.02500  1.000 9.90000  ? 62  PHE E CD2 1 
ATOM   5879 C CE1 . PHE E 2 62  ? -20.32600 23.19000  20.43100  1.000 10.63000 ? 62  PHE E CE1 1 
ATOM   5880 C CE2 . PHE E 2 62  ? -22.28300 23.38500  21.91500  1.000 8.14000  ? 62  PHE E CE2 1 
ATOM   5881 C CZ  . PHE E 2 62  ? -21.70500 23.37500  20.60900  1.000 12.09000 ? 62  PHE E CZ  1 
ATOM   5882 N N   . TYR E 2 63  ? -16.59000 21.16800  24.88400  1.000 12.09000 ? 63  TYR E N   1 
ATOM   5883 C CA  . TYR E 2 63  ? -15.53000 21.15500  25.87600  1.000 10.46000 ? 63  TYR E CA  1 
ATOM   5884 C C   . TYR E 2 63  ? -14.45000 22.14900  25.44900  1.000 13.48000 ? 63  TYR E C   1 
ATOM   5885 O O   . TYR E 2 63  ? -14.22500 22.37500  24.24800  1.000 10.51000 ? 63  TYR E O   1 
ATOM   5886 C CB  . TYR E 2 63  ? -14.90200 19.75700  26.09800  1.000 10.50000 ? 63  TYR E CB  1 
ATOM   5887 C CG  . TYR E 2 63  ? -14.24200 19.12600  24.90600  1.000 10.10000 ? 63  TYR E CG  1 
ATOM   5888 C CD1 . TYR E 2 63  ? -12.94300 19.43100  24.56700  1.000 14.41000 ? 63  TYR E CD1 1 
ATOM   5889 C CD2 . TYR E 2 63  ? -14.92500 18.19300  24.11900  1.000 14.53000 ? 63  TYR E CD2 1 
ATOM   5890 C CE1 . TYR E 2 63  ? -12.31300 18.83900  23.45400  1.000 13.15000 ? 63  TYR E CE1 1 
ATOM   5891 C CE2 . TYR E 2 63  ? -14.33200 17.58200  23.00000  1.000 14.27000 ? 63  TYR E CE2 1 
ATOM   5892 C CZ  . TYR E 2 63  ? -13.03600 17.90600  22.68800  1.000 18.13000 ? 63  TYR E CZ  1 
ATOM   5893 O OH  . TYR E 2 63  ? -12.47600 17.37300  21.57400  1.000 19.29000 ? 63  TYR E OH  1 
ATOM   5894 N N   . LEU E 2 64  ? -13.81100 22.76300  26.46600  1.000 11.89000 ? 64  LEU E N   1 
ATOM   5895 C CA  . LEU E 2 64  ? -12.75500 23.76400  26.28600  1.000 8.83000  ? 64  LEU E CA  1 
ATOM   5896 C C   . LEU E 2 64  ? -11.74400 23.58200  27.41100  1.000 9.82000  ? 64  LEU E C   1 
ATOM   5897 O O   . LEU E 2 64  ? -12.11700 23.30200  28.55100  1.000 11.05000 ? 64  LEU E O   1 
ATOM   5898 C CB  . LEU E 2 64  ? -13.31300 25.21800  26.36800  1.000 11.29000 ? 64  LEU E CB  1 
ATOM   5899 C CG  . LEU E 2 64  ? -14.21100 25.65000  25.18200  1.000 12.53000 ? 64  LEU E CG  1 
ATOM   5900 C CD1 . LEU E 2 64  ? -14.83500 26.98700  25.51500  1.000 10.97000 ? 64  LEU E CD1 1 
ATOM   5901 C CD2 . LEU E 2 64  ? -13.37600 25.80100  23.88600  1.000 13.12000 ? 64  LEU E CD2 1 
ATOM   5902 N N   . LEU E 2 65  ? -10.48700 23.79800  27.09100  1.000 11.78000 ? 65  LEU E N   1 
ATOM   5903 C CA  . LEU E 2 65  ? -9.42800  23.87800  28.08500  1.000 9.28000  ? 65  LEU E CA  1 
ATOM   5904 C C   . LEU E 2 65  ? -8.95000  25.33500  28.09100  1.000 13.46000 ? 65  LEU E C   1 
ATOM   5905 O O   . LEU E 2 65  ? -8.57600  25.86800  27.02500  1.000 13.03000 ? 65  LEU E O   1 
ATOM   5906 C CB  . LEU E 2 65  ? -8.28200  22.92200  27.70600  1.000 7.58000  ? 65  LEU E CB  1 
ATOM   5907 C CG  . LEU E 2 65  ? -7.07400  23.04700  28.67700  1.000 15.46000 ? 65  LEU E CG  1 
ATOM   5908 C CD1 . LEU E 2 65  ? -7.55200  22.49700  30.04100  1.000 10.27000 ? 65  LEU E CD1 1 
ATOM   5909 C CD2 . LEU E 2 65  ? -5.89100  22.25800  28.13900  1.000 11.86000 ? 65  LEU E CD2 1 
ATOM   5910 N N   . TYR E 2 66  ? -8.99900  25.96600  29.27900  1.000 9.10000  ? 66  TYR E N   1 
ATOM   5911 C CA  . TYR E 2 66  ? -8.38800  27.24800  29.58200  1.000 9.05000  ? 66  TYR E CA  1 
ATOM   5912 C C   . TYR E 2 66  ? -7.12900  26.99500  30.37800  1.000 13.37000 ? 66  TYR E C   1 
ATOM   5913 O O   . TYR E 2 66  ? -7.12300  26.13400  31.26400  1.000 11.93000 ? 66  TYR E O   1 
ATOM   5914 C CB  . TYR E 2 66  ? -9.30200  28.11500  30.43800  1.000 11.54000 ? 66  TYR E CB  1 
ATOM   5915 C CG  . TYR E 2 66  ? -10.47600 28.64400  29.63100  1.000 12.38000 ? 66  TYR E CG  1 
ATOM   5916 C CD1 . TYR E 2 66  ? -11.49400 27.79800  29.25900  1.000 12.93000 ? 66  TYR E CD1 1 
ATOM   5917 C CD2 . TYR E 2 66  ? -10.54100 29.99000  29.23300  1.000 15.69000 ? 66  TYR E CD2 1 
ATOM   5918 C CE1 . TYR E 2 66  ? -12.56800 28.29800  28.51000  1.000 13.10000 ? 66  TYR E CE1 1 
ATOM   5919 C CE2 . TYR E 2 66  ? -11.61100 30.47000  28.46300  1.000 18.00000 ? 66  TYR E CE2 1 
ATOM   5920 C CZ  . TYR E 2 66  ? -12.59800 29.57600  28.11800  1.000 16.79000 ? 66  TYR E CZ  1 
ATOM   5921 O OH  . TYR E 2 66  ? -13.73900 29.95100  27.42200  1.000 24.86000 ? 66  TYR E OH  1 
ATOM   5922 N N   . TYR E 2 67  ? -6.08800  27.78800  30.10900  1.000 10.07000 ? 67  TYR E N   1 
ATOM   5923 C CA  . TYR E 2 67  ? -4.81200  27.49000  30.75400  1.000 12.95000 ? 67  TYR E CA  1 
ATOM   5924 C C   . TYR E 2 67  ? -3.91800  28.72200  30.81100  1.000 13.00000 ? 67  TYR E C   1 
ATOM   5925 O O   . TYR E 2 67  ? -3.99400  29.62500  29.97300  1.000 13.52000 ? 67  TYR E O   1 
ATOM   5926 C CB  . TYR E 2 67  ? -4.10400  26.35600  30.02000  1.000 13.15000 ? 67  TYR E CB  1 
ATOM   5927 C CG  . TYR E 2 67  ? -3.82700  26.61000  28.56500  1.000 15.33000 ? 67  TYR E CG  1 
ATOM   5928 C CD1 . TYR E 2 67  ? -4.79800  26.32600  27.59700  1.000 19.33000 ? 67  TYR E CD1 1 
ATOM   5929 C CD2 . TYR E 2 67  ? -2.61800  27.16000  28.14800  1.000 22.21000 ? 67  TYR E CD2 1 
ATOM   5930 C CE1 . TYR E 2 67  ? -4.56200  26.56200  26.23700  1.000 23.88000 ? 67  TYR E CE1 1 
ATOM   5931 C CE2 . TYR E 2 67  ? -2.37900  27.39100  26.78500  1.000 26.57000 ? 67  TYR E CE2 1 
ATOM   5932 C CZ  . TYR E 2 67  ? -3.33300  27.07600  25.84000  1.000 27.99000 ? 67  TYR E CZ  1 
ATOM   5933 O OH  . TYR E 2 67  ? -3.11000  27.33800  24.47600  1.000 26.28000 ? 67  TYR E OH  1 
ATOM   5934 N N   . THR E 2 68  ? -3.04600  28.73200  31.81200  1.000 13.95000 ? 68  THR E N   1 
ATOM   5935 C CA  . THR E 2 68  ? -2.09800  29.81200  31.96500  1.000 14.89000 ? 68  THR E CA  1 
ATOM   5936 C C   . THR E 2 68  ? -0.85700  29.26000  32.67000  1.000 17.40000 ? 68  THR E C   1 
ATOM   5937 O O   . THR E 2 68  ? -0.95100  28.35700  33.50000  1.000 16.27000 ? 68  THR E O   1 
ATOM   5938 C CB  . THR E 2 68  ? -2.71600  30.95900  32.77800  1.000 14.45000 ? 68  THR E CB  1 
ATOM   5939 O OG1 . THR E 2 68  ? -1.87200  32.09900  32.70000  1.000 20.85000 ? 68  THR E OG1 1 
ATOM   5940 C CG2 . THR E 2 68  ? -2.88900  30.61100  34.22900  1.000 16.50000 ? 68  THR E CG2 1 
ATOM   5941 N N   . GLU E 2 69  ? 0.30200   29.81700  32.35300  1.000 21.70000 ? 69  GLU E N   1 
ATOM   5942 C CA  . GLU E 2 69  ? 1.50400   29.49400  33.13500  1.000 16.72000 ? 69  GLU E CA  1 
ATOM   5943 C C   . GLU E 2 69  ? 1.38400   30.02400  34.56600  1.000 18.93000 ? 69  GLU E C   1 
ATOM   5944 O O   . GLU E 2 69  ? 0.85800   31.10700  34.80300  1.000 23.06000 ? 69  GLU E O   1 
ATOM   5945 C CB  . GLU E 2 69  ? 2.70900   30.08000  32.40400  1.000 23.64000 ? 69  GLU E CB  1 
ATOM   5946 C CG  . GLU E 2 69  ? 4.04000   29.41200  32.74500  1.000 41.89000 ? 69  GLU E CG  1 
ATOM   5947 C CD  . GLU E 2 69  ? 5.09600   29.62000  31.65200  1.000 56.20000 ? 69  GLU E CD  1 
ATOM   5948 O OE1 . GLU E 2 69  ? 5.26200   30.80100  31.23400  1.000 52.37000 ? 69  GLU E OE1 1 
ATOM   5949 O OE2 . GLU E 2 69  ? 5.78000   28.62600  31.25700  1.000 48.20000 ? 69  GLU E OE2 1 
ATOM   5950 N N   . PHE E 2 70  ? 1.81100   29.23300  35.55800  1.000 21.33000 ? 70  PHE E N   1 
ATOM   5951 C CA  . PHE E 2 70  ? 1.80700   29.72800  36.92600  1.000 18.25000 ? 70  PHE E CA  1 
ATOM   5952 C C   . PHE E 2 70  ? 2.93600   29.04900  37.70300  1.000 26.32000 ? 70  PHE E C   1 
ATOM   5953 O O   . PHE E 2 70  ? 3.54600   28.09200  37.22400  1.000 18.76000 ? 70  PHE E O   1 
ATOM   5954 C CB  . PHE E 2 70  ? 0.44600   29.54300  37.60200  1.000 17.81000 ? 70  PHE E CB  1 
ATOM   5955 C CG  . PHE E 2 70  ? 0.19000   28.17800  38.20800  1.000 20.90000 ? 70  PHE E CG  1 
ATOM   5956 C CD1 . PHE E 2 70  ? 0.41600   26.99600  37.48700  1.000 18.21000 ? 70  PHE E CD1 1 
ATOM   5957 C CD2 . PHE E 2 70  ? -0.41300  28.07500  39.45500  1.000 19.53000 ? 70  PHE E CD2 1 
ATOM   5958 C CE1 . PHE E 2 70  ? 0.14200   25.75900  38.05700  1.000 16.24000 ? 70  PHE E CE1 1 
ATOM   5959 C CE2 . PHE E 2 70  ? -0.72000  26.82300  40.00800  1.000 17.82000 ? 70  PHE E CE2 1 
ATOM   5960 C CZ  . PHE E 2 70  ? -0.43000  25.66000  39.31800  1.000 13.82000 ? 70  PHE E CZ  1 
ATOM   5961 N N   . THR E 2 71  ? 3.22700   29.59500  38.88900  1.000 23.81000 ? 71  THR E N   1 
ATOM   5962 C CA  . THR E 2 71  ? 4.19800   29.02900  39.83200  1.000 23.14000 ? 71  THR E CA  1 
ATOM   5963 C C   . THR E 2 71  ? 3.55100   28.89100  41.19800  1.000 21.57000 ? 71  THR E C   1 
ATOM   5964 O O   . THR E 2 71  ? 3.46000   29.87500  41.95300  1.000 30.98000 ? 71  THR E O   1 
ATOM   5965 C CB  . THR E 2 71  ? 5.44900   29.88400  39.93900  1.000 25.52000 ? 71  THR E CB  1 
ATOM   5966 O OG1 . THR E 2 71  ? 6.12400   29.84800  38.69400  1.000 25.47000 ? 71  THR E OG1 1 
ATOM   5967 C CG2 . THR E 2 71  ? 6.42800   29.29100  41.05700  1.000 23.95000 ? 71  THR E CG2 1 
ATOM   5968 N N   . PRO E 2 72  ? 3.10200   27.70900  41.55900  1.000 17.35000 ? 72  PRO E N   1 
ATOM   5969 C CA  . PRO E 2 72  ? 2.36600   27.57000  42.80600  1.000 23.28000 ? 72  PRO E CA  1 
ATOM   5970 C C   . PRO E 2 72  ? 3.26900   27.82000  44.00200  1.000 29.62000 ? 72  PRO E C   1 
ATOM   5971 O O   . PRO E 2 72  ? 4.48900   27.62700  43.96100  1.000 24.50000 ? 72  PRO E O   1 
ATOM   5972 C CB  . PRO E 2 72  ? 1.86000   26.12900  42.76900  1.000 27.64000 ? 72  PRO E CB  1 
ATOM   5973 C CG  . PRO E 2 72  ? 2.78300   25.42200  41.77200  1.000 23.66000 ? 72  PRO E CG  1 
ATOM   5974 C CD  . PRO E 2 72  ? 3.20800   26.44300  40.79700  1.000 23.13000 ? 72  PRO E CD  1 
ATOM   5975 N N   . THR E 2 73  ? 2.64600   28.26700  45.07300  1.000 30.43000 ? 73  THR E N   1 
ATOM   5976 C CA  . THR E 2 73  ? 3.33700   28.49200  46.33600  1.000 31.69000 ? 73  THR E CA  1 
ATOM   5977 C C   . THR E 2 73  ? 2.52900   27.80200  47.40800  1.000 32.89000 ? 73  THR E C   1 
ATOM   5978 O O   . THR E 2 73  ? 1.42200   27.29900  47.15900  1.000 31.54000 ? 73  THR E O   1 
ATOM   5979 C CB  . THR E 2 73  ? 3.48500   29.98600  46.66900  1.000 28.61000 ? 73  THR E CB  1 
ATOM   5980 O OG1 . THR E 2 73  ? 2.18700   30.52600  46.92400  1.000 29.64000 ? 73  THR E OG1 1 
ATOM   5981 C CG2 . THR E 2 73  ? 4.14200   30.73800  45.58000  1.000 24.76000 ? 73  THR E CG2 1 
ATOM   5982 N N   . GLU E 2 74  ? 3.05300   27.80200  48.63300  1.000 34.20000 ? 74  GLU E N   1 
ATOM   5983 C CA  . GLU E 2 74  ? 2.24500   27.22400  49.69300  1.000 30.39000 ? 74  GLU E CA  1 
ATOM   5984 C C   . GLU E 2 74  ? 1.01600   28.09300  49.92200  1.000 30.49000 ? 74  GLU E C   1 
ATOM   5985 O O   . GLU E 2 74  ? -0.07800  27.57400  50.17400  1.000 33.65000 ? 74  GLU E O   1 
ATOM   5986 C CB  . GLU E 2 74  ? 3.05300   27.10000  50.99400  1.000 32.55000 ? 74  GLU E CB  1 
ATOM   5987 C CG  . GLU E 2 74  ? 2.18400   26.72500  52.19500  1.000 38.59000 ? 74  GLU E CG  1 
ATOM   5988 C CD  . GLU E 2 74  ? 2.96200   26.78400  53.52900  1.000 56.19000 ? 74  GLU E CD  1 
ATOM   5989 O OE1 . GLU E 2 74  ? 4.11500   27.30700  53.53900  1.000 52.57000 ? 74  GLU E OE1 1 
ATOM   5990 O OE2 . GLU E 2 74  ? 2.43100   26.27100  54.54400  1.000 54.73000 ? 74  GLU E OE2 1 
ATOM   5991 N N   . LYS E 2 75  ? 1.17400   29.41700  49.79900  1.000 25.75000 ? 75  LYS E N   1 
ATOM   5992 C CA  . LYS E 2 75  ? 0.16400   30.35700  50.25700  1.000 37.28000 ? 75  LYS E CA  1 
ATOM   5993 C C   . LYS E 2 75  ? -0.81800  30.82500  49.17600  1.000 39.31000 ? 75  LYS E C   1 
ATOM   5994 O O   . LYS E 2 75  ? -1.93600  31.23200  49.52900  1.000 38.47000 ? 75  LYS E O   1 
ATOM   5995 C CB  . LYS E 2 75  ? 0.82300   31.60500  50.86900  1.000 37.02000 ? 75  LYS E CB  1 
ATOM   5996 C CG  . LYS E 2 75  ? 1.63100   32.43700  49.87400  1.000 44.37000 ? 75  LYS E CG  1 
ATOM   5997 C CD  . LYS E 2 75  ? 2.62000   33.39900  50.56900  1.000 47.93000 ? 75  LYS E CD  1 
ATOM   5998 C CE  . LYS E 2 75  ? 3.82300   33.73000  49.63900  1.000 60.68000 ? 75  LYS E CE  1 
ATOM   5999 N NZ  . LYS E 2 75  ? 4.63800   32.53700  49.13000  1.000 39.99000 ? 75  LYS E NZ  1 
ATOM   6000 N N   . ASP E 2 76  ? -0.44000  30.83000  47.89300  1.000 30.52000 ? 76  ASP E N   1 
ATOM   6001 C CA  . ASP E 2 76  ? -1.30300  31.41600  46.86100  1.000 32.64000 ? 76  ASP E CA  1 
ATOM   6002 C C   . ASP E 2 76  ? -2.44800  30.47000  46.51900  1.000 28.38000 ? 76  ASP E C   1 
ATOM   6003 O O   . ASP E 2 76  ? -2.25700  29.26400  46.34500  1.000 25.41000 ? 76  ASP E O   1 
ATOM   6004 C CB  . ASP E 2 76  ? -0.51600  31.75500  45.59800  1.000 25.23000 ? 76  ASP E CB  1 
ATOM   6005 C CG  . ASP E 2 76  ? 0.41200   32.93000  45.79800  1.000 39.79000 ? 76  ASP E CG  1 
ATOM   6006 O OD1 . ASP E 2 76  ? 0.00200   33.89100  46.49000  1.000 35.20000 ? 76  ASP E OD1 1 
ATOM   6007 O OD2 . ASP E 2 76  ? 1.53800   32.90200  45.25600  1.000 30.99000 ? 76  ASP E OD2 1 
ATOM   6008 N N   . GLU E 2 77  ? -3.63700  31.03600  46.41000  1.000 24.94000 ? 77  GLU E N   1 
ATOM   6009 C CA  . GLU E 2 77  ? -4.86500  30.30400  46.14500  1.000 25.23000 ? 77  GLU E CA  1 
ATOM   6010 C C   . GLU E 2 77  ? -5.22600  30.50200  44.67600  1.000 22.85000 ? 77  GLU E C   1 
ATOM   6011 O O   . GLU E 2 77  ? -5.35100  31.64800  44.20300  1.000 20.27000 ? 77  GLU E O   1 
ATOM   6012 C CB  . GLU E 2 77  ? -6.01400  30.81700  47.02600  1.000 26.51000 ? 77  GLU E CB  1 
ATOM   6013 C CG  . GLU E 2 77  ? -5.59400  31.04500  48.50100  1.000 41.37000 ? 77  GLU E CG  1 
ATOM   6014 C CD  . GLU E 2 77  ? -6.38800  32.19600  49.24200  1.000 60.66000 ? 77  GLU E CD  1 
ATOM   6015 O OE1 . GLU E 2 77  ? -7.64600  32.11000  49.36900  1.000 52.13000 ? 77  GLU E OE1 1 
ATOM   6016 O OE2 . GLU E 2 77  ? -5.74100  33.17700  49.72500  1.000 52.97000 ? 77  GLU E OE2 1 
ATOM   6017 N N   . TYR E 2 78  ? -5.43600  29.40000  43.96800  1.000 18.91000 ? 78  TYR E N   1 
ATOM   6018 C CA  . TYR E 2 78  ? -5.88400  29.49300  42.58100  1.000 18.73000 ? 78  TYR E CA  1 
ATOM   6019 C C   . TYR E 2 78  ? -7.28600  28.89900  42.47800  1.000 20.62000 ? 78  TYR E C   1 
ATOM   6020 O O   . TYR E 2 78  ? -7.68400  28.01800  43.25200  1.000 18.67000 ? 78  TYR E O   1 
ATOM   6021 C CB  . TYR E 2 78  ? -4.88300  28.79700  41.62900  1.000 15.10000 ? 78  TYR E CB  1 
ATOM   6022 C CG  . TYR E 2 78  ? -3.57800  29.55300  41.55900  1.000 18.70000 ? 78  TYR E CG  1 
ATOM   6023 C CD1 . TYR E 2 78  ? -3.40700  30.58700  40.63200  1.000 18.95000 ? 78  TYR E CD1 1 
ATOM   6024 C CD2 . TYR E 2 78  ? -2.54000  29.29300  42.45900  1.000 20.00000 ? 78  TYR E CD2 1 
ATOM   6025 C CE1 . TYR E 2 78  ? -2.23000  31.30300  40.56000  1.000 17.14000 ? 78  TYR E CE1 1 
ATOM   6026 C CE2 . TYR E 2 78  ? -1.33900  30.01100  42.39600  1.000 18.57000 ? 78  TYR E CE2 1 
ATOM   6027 C CZ  . TYR E 2 78  ? -1.20000  31.00700  41.44100  1.000 22.95000 ? 78  TYR E CZ  1 
ATOM   6028 O OH  . TYR E 2 78  ? -0.05000  31.74500  41.39200  1.000 22.45000 ? 78  TYR E OH  1 
ATOM   6029 N N   . ALA E 2 79  ? -8.05500  29.40200  41.51900  1.000 16.93000 ? 79  ALA E N   1 
ATOM   6030 C CA  . ALA E 2 79  ? -9.40800  28.91200  41.34700  1.000 18.93000 ? 79  ALA E CA  1 
ATOM   6031 C C   . ALA E 2 79  ? -9.83400  29.14700  39.90700  1.000 18.96000 ? 79  ALA E C   1 
ATOM   6032 O O   . ALA E 2 79  ? -9.24800  29.96100  39.18400  1.000 15.57000 ? 79  ALA E O   1 
ATOM   6033 C CB  . ALA E 2 79  ? -10.38900 29.60200  42.29500  1.000 14.59000 ? 79  ALA E CB  1 
ATOM   6034 N N   . CYS E 2 80  ? -10.89100 28.45200  39.52000  1.000 14.29000 ? 80  CYS E N   1 
ATOM   6035 C CA  . CYS E 2 80  ? -11.53200 28.70500  38.23400  1.000 17.11000 ? 80  CYS E CA  1 
ATOM   6036 C C   . CYS E 2 80  ? -12.91600 29.27500  38.50500  1.000 17.55000 ? 80  CYS E C   1 
ATOM   6037 O O   . CYS E 2 80  ? -13.58000 28.84000  39.45100  1.000 23.98000 ? 80  CYS E O   1 
ATOM   6038 C CB  . CYS E 2 80  ? -11.60900 27.37900  37.42000  1.000 19.20000 ? 80  CYS E CB  1 
ATOM   6039 S SG  . CYS E 2 80  ? -12.20900 27.55800  35.71600  1.000 28.40000 ? 80  CYS E SG  1 
ATOM   6040 N N   . ARG E 2 81  ? -13.36300 30.25600  37.69700  1.000 12.65000 ? 81  ARG E N   1 
ATOM   6041 C CA  . ARG E 2 81  ? -14.69800 30.84400  37.86500  1.000 15.42000 ? 81  ARG E CA  1 
ATOM   6042 C C   . ARG E 2 81  ? -15.44100 30.74700  36.54700  1.000 16.07000 ? 81  ARG E C   1 
ATOM   6043 O O   . ARG E 2 81  ? -14.97600 31.29600  35.53000  1.000 17.83000 ? 81  ARG E O   1 
ATOM   6044 C CB  . ARG E 2 81  ? -14.61500 32.31200  38.29300  1.000 17.26000 ? 81  ARG E CB  1 
ATOM   6045 C CG  . ARG E 2 81  ? -16.02100 32.96900  38.34700  1.000 20.27000 ? 81  ARG E CG  1 
ATOM   6046 C CD  . ARG E 2 81  ? -15.92700 34.38100  38.95300  1.000 25.36000 ? 81  ARG E CD  1 
ATOM   6047 N NE  . ARG E 2 81  ? -15.09700 35.23900  38.10000  1.000 24.66000 ? 81  ARG E NE  1 
ATOM   6048 C CZ  . ARG E 2 81  ? -14.44900 36.32500  38.50700  1.000 31.08000 ? 81  ARG E CZ  1 
ATOM   6049 N NH1 . ARG E 2 81  ? -14.40700 36.67300  39.80400  1.000 23.62000 ? 81  ARG E NH1 1 
ATOM   6050 N NH2 . ARG E 2 81  ? -13.84200 37.08700  37.59900  1.000 29.78000 ? 81  ARG E NH2 1 
ATOM   6051 N N   . VAL E 2 82  ? -16.55000 30.03400  36.55100  1.000 14.47000 ? 82  VAL E N   1 
ATOM   6052 C CA  . VAL E 2 82  ? -17.28600 29.70700  35.32900  1.000 12.47000 ? 82  VAL E CA  1 
ATOM   6053 C C   . VAL E 2 82  ? -18.67600 30.32500  35.40700  1.000 16.84000 ? 82  VAL E C   1 
ATOM   6054 O O   . VAL E 2 82  ? -19.36100 30.18100  36.42500  1.000 16.92000 ? 82  VAL E O   1 
ATOM   6055 C CB  . VAL E 2 82  ? -17.37600 28.17200  35.14600  1.000 12.50000 ? 82  VAL E CB  1 
ATOM   6056 C CG1 . VAL E 2 82  ? -18.25000 27.78100  33.96900  1.000 13.04000 ? 82  VAL E CG1 1 
ATOM   6057 C CG2 . VAL E 2 82  ? -15.94700 27.53600  35.02900  1.000 12.49000 ? 82  VAL E CG2 1 
ATOM   6058 N N   . ASN E 2 83  ? -19.10900 30.97100  34.32200  1.000 17.81000 ? 83  ASN E N   1 
ATOM   6059 C CA  . ASN E 2 83  ? -20.51600 31.33200  34.15000  1.000 15.39000 ? 83  ASN E CA  1 
ATOM   6060 C C   . ASN E 2 83  ? -21.04600 30.74900  32.83300  1.000 20.01000 ? 83  ASN E C   1 
ATOM   6061 O O   . ASN E 2 83  ? -20.31900 30.66500  31.82000  1.000 15.52000 ? 83  ASN E O   1 
ATOM   6062 C CB  . ASN E 2 83  ? -20.70900 32.83700  34.14900  1.000 18.63000 ? 83  ASN E CB  1 
ATOM   6063 C CG  . ASN E 2 83  ? -22.14200 33.23200  34.59000  1.000 38.06000 ? 83  ASN E CG  1 
ATOM   6064 O OD1 . ASN E 2 83  ? -22.98400 32.37900  35.02300  1.000 25.24000 ? 83  ASN E OD1 1 
ATOM   6065 N ND2 . ASN E 2 83  ? -22.42100 34.53200  34.51200  1.000 48.53000 ? 83  ASN E ND2 1 
ATOM   6066 N N   . HIS E 2 84  ? -22.32000 30.36600  32.87600  1.000 14.47000 ? 84  HIS E N   1 
ATOM   6067 C CA  . HIS E 2 84  ? -23.00800 29.69500  31.79600  1.000 15.07000 ? 84  HIS E CA  1 
ATOM   6068 C C   . HIS E 2 84  ? -24.49100 29.98800  31.99200  1.000 20.88000 ? 84  HIS E C   1 
ATOM   6069 O O   . HIS E 2 84  ? -24.92500 30.29400  33.11500  1.000 19.98000 ? 84  HIS E O   1 
ATOM   6070 C CB  . HIS E 2 84  ? -22.74400 28.18200  31.82800  1.000 15.83000 ? 84  HIS E CB  1 
ATOM   6071 C CG  . HIS E 2 84  ? -23.26800 27.44500  30.62200  1.000 18.03000 ? 84  HIS E CG  1 
ATOM   6072 N ND1 . HIS E 2 84  ? -24.39100 26.62500  30.67700  1.000 18.58000 ? 84  HIS E ND1 1 
ATOM   6073 C CD2 . HIS E 2 84  ? -22.84500 27.43500  29.31900  1.000 14.58000 ? 84  HIS E CD2 1 
ATOM   6074 C CE1 . HIS E 2 84  ? -24.59400 26.09400  29.47000  1.000 17.73000 ? 84  HIS E CE1 1 
ATOM   6075 N NE2 . HIS E 2 84  ? -23.68100 26.58100  28.63100  1.000 14.07000 ? 84  HIS E NE2 1 
ATOM   6076 N N   . VAL E 2 85  ? -25.27900 29.81900  30.91600  1.000 15.57000 ? 85  VAL E N   1 
ATOM   6077 C CA  . VAL E 2 85  ? -26.69200 30.17600  31.01700  1.000 19.46000 ? 85  VAL E CA  1 
ATOM   6078 C C   . VAL E 2 85  ? -27.38200 29.25400  31.98900  1.000 18.70000 ? 85  VAL E C   1 
ATOM   6079 O O   . VAL E 2 85  ? -28.36100 29.64200  32.60800  1.000 23.10000 ? 85  VAL E O   1 
ATOM   6080 C CB  . VAL E 2 85  ? -27.38400 30.16700  29.61600  1.000 20.43000 ? 85  VAL E CB  1 
ATOM   6081 C CG1 . VAL E 2 85  ? -27.48100 28.72700  29.01100  1.000 16.63000 ? 85  VAL E CG1 1 
ATOM   6082 C CG2 . VAL E 2 85  ? -28.74400 30.86700  29.70400  1.000 22.90000 ? 85  VAL E CG2 1 
ATOM   6083 N N   . THR E 2 86  ? -26.84700 28.05600  32.20700  1.000 16.62000 ? 86  THR E N   1 
ATOM   6084 C CA  . THR E 2 86  ? -27.47700 27.12200  33.11800  1.000 20.61000 ? 86  THR E CA  1 
ATOM   6085 C C   . THR E 2 86  ? -27.20500 27.45000  34.59300  1.000 25.28000 ? 86  THR E C   1 
ATOM   6086 O O   . THR E 2 86  ? -27.77800 26.79500  35.44800  1.000 23.45000 ? 86  THR E O   1 
ATOM   6087 C CB  . THR E 2 86  ? -26.99100 25.70600  32.86300  1.000 17.93000 ? 86  THR E CB  1 
ATOM   6088 O OG1 . THR E 2 86  ? -25.56900 25.71400  33.02200  1.000 21.74000 ? 86  THR E OG1 1 
ATOM   6089 C CG2 . THR E 2 86  ? -27.33000 25.20700  31.43300  1.000 16.22000 ? 86  THR E CG2 1 
ATOM   6090 N N   . LEU E 2 87  ? -26.33300 28.40500  34.91700  1.000 20.04000 ? 87  LEU E N   1 
ATOM   6091 C CA  . LEU E 2 87  ? -25.98700 28.69700  36.31200  1.000 21.19000 ? 87  LEU E CA  1 
ATOM   6092 C C   . LEU E 2 87  ? -26.64900 29.99200  36.79400  1.000 27.19000 ? 87  LEU E C   1 
ATOM   6093 O O   . LEU E 2 87  ? -26.55000 31.03900  36.13700  1.000 28.41000 ? 87  LEU E O   1 
ATOM   6094 C CB  . LEU E 2 87  ? -24.46900 28.81800  36.48900  1.000 23.52000 ? 87  LEU E CB  1 
ATOM   6095 C CG  . LEU E 2 87  ? -23.65800 27.58400  36.05100  1.000 21.94000 ? 87  LEU E CG  1 
ATOM   6096 C CD1 . LEU E 2 87  ? -22.15800 27.99200  35.98000  1.000 17.25000 ? 87  LEU E CD1 1 
ATOM   6097 C CD2 . LEU E 2 87  ? -23.87100 26.51000  37.09400  1.000 23.96000 ? 87  LEU E CD2 1 
ATOM   6098 N N   . SER E 2 88  ? -27.25600 29.94400  37.98900  1.000 24.99000 ? 88  SER E N   1 
ATOM   6099 C CA  . SER E 2 88  ? -27.86200 31.16500  38.50700  1.000 25.56000 ? 88  SER E CA  1 
ATOM   6100 C C   . SER E 2 88  ? -26.81900 32.19500  38.92100  1.000 31.67000 ? 88  SER E C   1 
ATOM   6101 O O   . SER E 2 88  ? -27.13500 33.38200  38.97400  1.000 32.35000 ? 88  SER E O   1 
ATOM   6102 C CB  . SER E 2 88  ? -28.75900 30.81800  39.67600  1.000 25.90000 ? 88  SER E CB  1 
ATOM   6103 O OG  . SER E 2 88  ? -28.04500 30.12800  40.70000  1.000 31.62000 ? 88  SER E OG  1 
ATOM   6104 N N   . GLN E 2 89  ? -25.59000 31.77500  39.25200  1.000 26.10000 ? 89  GLN E N   1 
ATOM   6105 C CA  . GLN E 2 89  ? -24.49800 32.67300  39.61500  1.000 23.80000 ? 89  GLN E CA  1 
ATOM   6106 C C   . GLN E 2 89  ? -23.19500 31.97200  39.24400  1.000 21.54000 ? 89  GLN E C   1 
ATOM   6107 O O   . GLN E 2 89  ? -23.18700 30.75800  39.07800  1.000 21.70000 ? 89  GLN E O   1 
ATOM   6108 C CB  . GLN E 2 89  ? -24.50500 32.99800  41.12300  1.000 28.55000 ? 89  GLN E CB  1 
ATOM   6109 C CG  . GLN E 2 89  ? -24.16000 31.81400  42.01800  1.000 23.54000 ? 89  GLN E CG  1 
ATOM   6110 C CD  . GLN E 2 89  ? -24.29500 32.17500  43.53800  1.000 40.04000 ? 89  GLN E CD  1 
ATOM   6111 O OE1 . GLN E 2 89  ? -25.39400 32.43400  43.99600  1.000 36.03000 ? 89  GLN E OE1 1 
ATOM   6112 N NE2 . GLN E 2 89  ? -23.17600 32.22300  44.28200  1.000 35.64000 ? 89  GLN E NE2 1 
ATOM   6113 N N   . PRO E 2 90  ? -22.07300 32.68100  39.20800  1.000 25.16000 ? 90  PRO E N   1 
ATOM   6114 C CA  . PRO E 2 90  ? -20.83100 32.01000  38.77900  1.000 24.75000 ? 90  PRO E CA  1 
ATOM   6115 C C   . PRO E 2 90  ? -20.46800 30.88900  39.73600  1.000 25.06000 ? 90  PRO E C   1 
ATOM   6116 O O   . PRO E 2 90  ? -20.69400 30.98400  40.94100  1.000 20.94000 ? 90  PRO E O   1 
ATOM   6117 C CB  . PRO E 2 90  ? -19.78400 33.12400  38.78600  1.000 22.84000 ? 90  PRO E CB  1 
ATOM   6118 C CG  . PRO E 2 90  ? -20.54800 34.38200  38.73100  1.000 34.80000 ? 90  PRO E CG  1 
ATOM   6119 C CD  . PRO E 2 90  ? -21.91500 34.13400  39.31900  1.000 26.93000 ? 90  PRO E CD  1 
ATOM   6120 N N   . LYS E 2 91  ? -19.94700 29.79800  39.18300  1.000 20.72000 ? 91  LYS E N   1 
ATOM   6121 C CA  . LYS E 2 91  ? -19.38300 28.70200  39.97400  1.000 21.00000 ? 91  LYS E CA  1 
ATOM   6122 C C   . LYS E 2 91  ? -17.87300 28.89600  40.16600  1.000 19.76000 ? 91  LYS E C   1 
ATOM   6123 O O   . LYS E 2 91  ? -17.15100 29.04700  39.18300  1.000 19.23000 ? 91  LYS E O   1 
ATOM   6124 C CB  . LYS E 2 91  ? -19.64300 27.37700  39.25900  1.000 19.70000 ? 91  LYS E CB  1 
ATOM   6125 C CG  . LYS E 2 91  ? -19.86100 26.18500  40.13900  1.000 28.08000 ? 91  LYS E CG  1 
ATOM   6126 C CD  . LYS E 2 91  ? -20.39900 25.04700  39.30100  1.000 31.35000 ? 91  LYS E CD  1 
ATOM   6127 C CE  . LYS E 2 91  ? -21.91600 24.84500  39.38600  1.000 29.53000 ? 91  LYS E CE  1 
ATOM   6128 N NZ  . LYS E 2 91  ? -22.27100 23.39100  39.17800  1.000 26.03000 ? 91  LYS E NZ  1 
ATOM   6129 N N   . ILE E 2 92  ? -17.38800 28.80000  41.40200  1.000 16.20000 ? 92  ILE E N   1 
ATOM   6130 C CA  . ILE E 2 92  ? -15.95600 28.95100  41.71700  1.000 18.80000 ? 92  ILE E CA  1 
ATOM   6131 C C   . ILE E 2 92  ? -15.47300 27.60500  42.17900  1.000 20.94000 ? 92  ILE E C   1 
ATOM   6132 O O   . ILE E 2 92  ? -16.04400 27.05500  43.12000  1.000 21.14000 ? 92  ILE E O   1 
ATOM   6133 C CB  . ILE E 2 92  ? -15.70600 29.96900  42.84000  1.000 19.18000 ? 92  ILE E CB  1 
ATOM   6134 C CG1 . ILE E 2 92  ? -16.41900 31.29900  42.56500  1.000 27.92000 ? 92  ILE E CG1 1 
ATOM   6135 C CG2 . ILE E 2 92  ? -14.19600 30.15100  43.11600  1.000 19.64000 ? 92  ILE E CG2 1 
ATOM   6136 C CD1 . ILE E 2 92  ? -15.71700 32.14000  41.65900  1.000 31.18000 ? 92  ILE E CD1 1 
ATOM   6137 N N   . VAL E 2 93  ? -14.46600 27.04700  41.51100  1.000 14.79000 ? 93  VAL E N   1 
ATOM   6138 C CA  . VAL E 2 93  ? -13.86000 25.79100  41.94300  1.000 15.58000 ? 93  VAL E CA  1 
ATOM   6139 C C   . VAL E 2 93  ? -12.42600 26.09300  42.30200  1.000 17.31000 ? 93  VAL E C   1 
ATOM   6140 O O   . VAL E 2 93  ? -11.65400 26.56000  41.46200  1.000 14.62000 ? 93  VAL E O   1 
ATOM   6141 C CB  . VAL E 2 93  ? -13.92700 24.70200  40.86800  1.000 18.15000 ? 93  VAL E CB  1 
ATOM   6142 C CG1 . VAL E 2 93  ? -13.33800 23.36800  41.43400  1.000 18.52000 ? 93  VAL E CG1 1 
ATOM   6143 C CG2 . VAL E 2 93  ? -15.31600 24.54600  40.44800  1.000 16.45000 ? 93  VAL E CG2 1 
ATOM   6144 N N   . LYS E 2 94  ? -12.05900 25.83000  43.54400  1.000 15.63000 ? 94  LYS E N   1 
ATOM   6145 C CA  . LYS E 2 94  ? -10.69700 26.08500  43.99000  1.000 16.20000 ? 94  LYS E CA  1 
ATOM   6146 C C   . LYS E 2 94  ? -9.74400  25.02600  43.44500  1.000 17.47000 ? 94  LYS E C   1 
ATOM   6147 O O   . LYS E 2 94  ? -10.10200 23.84800  43.36600  1.000 19.60000 ? 94  LYS E O   1 
ATOM   6148 C CB  . LYS E 2 94  ? -10.66200 26.10000  45.54500  1.000 14.98000 ? 94  LYS E CB  1 
ATOM   6149 C CG  . LYS E 2 94  ? -11.00800 27.49000  46.22600  1.000 41.05000 ? 94  LYS E CG  1 
ATOM   6150 C CD  . LYS E 2 94  ? -10.80400 27.56100  47.82100  1.000 48.12000 ? 94  LYS E CD  1 
ATOM   6151 C CE  . LYS E 2 94  ? -11.89100 28.42600  48.62100  1.000 27.41000 ? 94  LYS E CE  1 
ATOM   6152 N NZ  . LYS E 2 94  ? -12.71800 29.33900  47.66200  1.000 32.68000 ? 94  LYS E NZ  1 
ATOM   6153 N N   . TRP E 2 95  ? -8.50600  25.43300  43.12500  1.000 15.32000 ? 95  TRP E N   1 
ATOM   6154 C CA  . TRP E 2 95  ? -7.46300  24.47000  42.76100  1.000 14.06000 ? 95  TRP E CA  1 
ATOM   6155 C C   . TRP E 2 95  ? -6.97500  23.71600  44.00200  1.000 20.47000 ? 95  TRP E C   1 
ATOM   6156 O O   . TRP E 2 95  ? -6.49200  24.32200  44.95900  1.000 19.12000 ? 95  TRP E O   1 
ATOM   6157 C CB  . TRP E 2 95  ? -6.28800  25.14700  42.09100  1.000 13.14000 ? 95  TRP E CB  1 
ATOM   6158 C CG  . TRP E 2 95  ? -5.22100  24.15600  41.75900  1.000 16.05000 ? 95  TRP E CG  1 
ATOM   6159 C CD1 . TRP E 2 95  ? -5.36200  22.95700  41.06800  1.000 18.04000 ? 95  TRP E CD1 1 
ATOM   6160 C CD2 . TRP E 2 95  ? -3.85200  24.25500  42.10800  1.000 17.16000 ? 95  TRP E CD2 1 
ATOM   6161 N NE1 . TRP E 2 95  ? -4.12500  22.32800  40.96900  1.000 14.08000 ? 95  TRP E NE1 1 
ATOM   6162 C CE2 . TRP E 2 95  ? -3.19400  23.11100  41.60700  1.000 16.58000 ? 95  TRP E CE2 1 
ATOM   6163 C CE3 . TRP E 2 95  ? -3.11200  25.20200  42.82300  1.000 20.68000 ? 95  TRP E CE3 1 
ATOM   6164 C CZ2 . TRP E 2 95  ? -1.84800  22.89100  41.81600  1.000 19.72000 ? 95  TRP E CZ2 1 
ATOM   6165 C CZ3 . TRP E 2 95  ? -1.77900  24.99800  42.98900  1.000 23.87000 ? 95  TRP E CZ3 1 
ATOM   6166 C CH2 . TRP E 2 95  ? -1.15400  23.85000  42.48700  1.000 20.30000 ? 95  TRP E CH2 1 
ATOM   6167 N N   . ASP E 2 96  ? -7.10000  22.39200  43.97600  1.000 23.49000 ? 96  ASP E N   1 
ATOM   6168 C CA  . ASP E 2 96  ? -6.58100  21.47300  44.99500  1.000 18.46000 ? 96  ASP E CA  1 
ATOM   6169 C C   . ASP E 2 96  ? -5.49300  20.64500  44.31400  1.000 22.57000 ? 96  ASP E C   1 
ATOM   6170 O O   . ASP E 2 96  ? -5.78800  19.85600  43.39700  1.000 19.37000 ? 96  ASP E O   1 
ATOM   6171 C CB  . ASP E 2 96  ? -7.72600  20.59700  45.48600  1.000 23.36000 ? 96  ASP E CB  1 
ATOM   6172 C CG  . ASP E 2 96  ? -7.31200  19.62600  46.58300  1.000 21.44000 ? 96  ASP E CG  1 
ATOM   6173 O OD1 . ASP E 2 96  ? -6.12600  19.37300  46.75700  1.000 22.25000 ? 96  ASP E OD1 1 
ATOM   6174 O OD2 . ASP E 2 96  ? -8.21700  19.09700  47.18500  1.000 26.02000 ? 96  ASP E OD2 1 
ATOM   6175 N N   . ARG E 2 97  ? -4.23500  20.80700  44.73200  1.000 22.02000 ? 97  ARG E N   1 
ATOM   6176 C CA  . ARG E 2 97  ? -3.16100  20.07600  44.04100  1.000 18.61000 ? 97  ARG E CA  1 
ATOM   6177 C C   . ARG E 2 97  ? -3.24000  18.54500  44.18100  1.000 24.99000 ? 97  ARG E C   1 
ATOM   6178 O O   . ARG E 2 97  ? -2.48500  17.83600  43.49200  1.000 25.46000 ? 97  ARG E O   1 
ATOM   6179 C CB  . ARG E 2 97  ? -1.79000  20.53800  44.55000  1.000 23.02000 ? 97  ARG E CB  1 
ATOM   6180 C CG  . ARG E 2 97  ? -1.51200  20.07300  45.98800  1.000 30.47000 ? 97  ARG E CG  1 
ATOM   6181 C CD  . ARG E 2 97  ? -0.18900  20.69600  46.49700  1.000 35.71000 ? 97  ARG E CD  1 
ATOM   6182 N NE  . ARG E 2 97  ? -0.27000  22.15900  46.51900  1.000 29.06000 ? 97  ARG E NE  1 
ATOM   6183 C CZ  . ARG E 2 97  ? 0.74800   23.00400  46.36800  1.000 37.07000 ? 97  ARG E CZ  1 
ATOM   6184 N NH1 . ARG E 2 97  ? 1.99300   22.57700  46.20000  1.000 30.20000 ? 97  ARG E NH1 1 
ATOM   6185 N NH2 . ARG E 2 97  ? 0.51100   24.31100  46.39100  1.000 30.24000 ? 97  ARG E NH2 1 
ATOM   6186 N N   . ASP E 2 98  ? -4.08600  18.01600  45.07200  1.000 22.79000 ? 98  ASP E N   1 
ATOM   6187 C CA  . ASP E 2 98  ? -4.29500  16.57200  45.20800  1.000 21.40000 ? 98  ASP E CA  1 
ATOM   6188 C C   . ASP E 2 98  ? -5.36300  16.07400  44.27000  1.000 23.25000 ? 98  ASP E C   1 
ATOM   6189 O O   . ASP E 2 98  ? -5.71400  14.88400  44.32100  1.000 21.26000 ? 98  ASP E O   1 
ATOM   6190 C CB  . ASP E 2 98  ? -4.72600  16.22900  46.63400  1.000 21.50000 ? 98  ASP E CB  1 
ATOM   6191 C CG  . ASP E 2 98  ? -3.60900  16.45900  47.64000  1.000 30.59000 ? 98  ASP E CG  1 
ATOM   6192 O OD1 . ASP E 2 98  ? -2.45400  16.54300  47.18300  1.000 28.66000 ? 98  ASP E OD1 1 
ATOM   6193 O OD2 . ASP E 2 98  ? -3.92800  16.60700  48.83700  1.000 38.29000 ? 98  ASP E OD2 1 
ATOM   6194 N N   . MET E 2 99  ? -5.92500  16.97200  43.46000  1.000 18.16000 ? 99  MET E N   1 
ATOM   6195 C CA  . MET E 2 99  ? -6.86400  16.55100  42.44400  1.000 19.15000 ? 99  MET E CA  1 
ATOM   6196 C C   . MET E 2 99  ? -6.56300  17.00800  40.97100  1.000 13.48000 ? 99  MET E C   1 
ATOM   6197 O O   . MET E 2 99  ? -7.47900  16.65600  40.15500  1.000 21.10000 ? 99  MET E O   1 
ATOM   6198 C CB  . MET E 2 99  ? -8.26200  17.01900  42.82900  1.000 15.35000 ? 99  MET E CB  1 
ATOM   6199 C CG  . MET E 2 99  ? -8.89400  16.32400  44.01700  1.000 26.69000 ? 99  MET E CG  1 
ATOM   6200 S SD  . MET E 2 99  ? -10.17200 17.39000  44.69600  1.000 38.25000 ? 99  MET E SD  1 
ATOM   6201 C CE  . MET E 2 99  ? -11.52700 16.19600  44.70000  1.000 46.23000 ? 99  MET E CE  1 
ATOM   6202 N N   . MET F 3 1   ? -7.68900  16.38300  5.62500   1.000 12.12000 ? 1   MET F N   1 
ATOM   6203 C CA  . MET F 3 1   ? -8.32000  17.08400  4.47300   1.000 13.19000 ? 1   MET F CA  1 
ATOM   6204 C C   . MET F 3 1   ? -9.83100  17.04600  4.55200   1.000 9.31000  ? 1   MET F C   1 
ATOM   6205 O O   . MET F 3 1   ? -10.47000 15.98600  4.65600   1.000 10.67000 ? 1   MET F O   1 
ATOM   6206 C CB  . MET F 3 1   ? -7.72800  16.57200  3.17400   1.000 13.50000 ? 1   MET F CB  1 
ATOM   6207 C CG  . MET F 3 1   ? -8.22800  17.54500  2.00100   1.000 22.36000 ? 1   MET F CG  1 
ATOM   6208 S SD  . MET F 3 1   ? -7.81100  16.96600  0.45400   1.000 29.39000 ? 1   MET F SD  1 
ATOM   6209 C CE  . MET F 3 1   ? -6.14000  17.63400  0.72500   1.000 21.87000 ? 1   MET F CE  1 
ATOM   6210 N N   . ALA F 3 2   ? -10.39800 18.25300  4.61900   1.000 9.36000  ? 2   ALA F N   1 
ATOM   6211 C CA  . ALA F 3 2   ? -11.81800 18.41800  4.88100   1.000 10.24000 ? 2   ALA F CA  1 
ATOM   6212 C C   . ALA F 3 2   ? -12.70600 18.13800  3.66100   1.000 13.57000 ? 2   ALA F C   1 
ATOM   6213 O O   . ALA F 3 2   ? -12.29200 18.13600  2.48300   1.000 11.90000 ? 2   ALA F O   1 
ATOM   6214 C CB  . ALA F 3 2   ? -12.08600 19.82900  5.43200   1.000 12.58000 ? 2   ALA F CB  1 
ATOM   6215 N N   . ARG F 3 3   ? -13.95900 17.82100  3.98100   1.000 12.39000 ? 3   ARG F N   1 
ATOM   6216 C CA  . ARG F 3 3   ? -14.98600 17.59300  2.99500   1.000 12.13000 ? 3   ARG F CA  1 
ATOM   6217 C C   . ARG F 3 3   ? -15.19100 18.84800  2.15500   1.000 13.09000 ? 3   ARG F C   1 
ATOM   6218 O O   . ARG F 3 3   ? -15.03800 19.96300  2.63900   1.000 13.95000 ? 3   ARG F O   1 
ATOM   6219 C CB  . ARG F 3 3   ? -16.26600 17.19200  3.75200   1.000 13.43000 ? 3   ARG F CB  1 
ATOM   6220 C CG  . ARG F 3 3   ? -17.44500 16.91500  2.86400   1.000 18.32000 ? 3   ARG F CG  1 
ATOM   6221 C CD  . ARG F 3 3   ? -17.42200 15.40500  2.47400   1.000 18.20000 ? 3   ARG F CD  1 
ATOM   6222 N NE  . ARG F 3 3   ? -18.77000 15.03500  2.07600   1.000 17.54000 ? 3   ARG F NE  1 
ATOM   6223 C CZ  . ARG F 3 3   ? -19.38000 15.54000  1.00800   1.000 21.02000 ? 3   ARG F CZ  1 
ATOM   6224 N NH1 . ARG F 3 3   ? -18.71600 16.22800  0.10200   1.000 21.90000 ? 3   ARG F NH1 1 
ATOM   6225 N NH2 . ARG F 3 3   ? -20.69600 15.36400  0.85600   1.000 16.03000 ? 3   ARG F NH2 1 
ATOM   6226 N N   . GLU F 3 4   ? -15.51400 18.66100  0.87000   1.000 11.95000 ? 4   GLU F N   1 
ATOM   6227 C CA  . GLU F 3 4   ? -15.93000 19.79400  0.05600   1.000 15.35000 ? 4   GLU F CA  1 
ATOM   6228 C C   . GLU F 3 4   ? -17.22000 20.43200  0.61300   1.000 17.65000 ? 4   GLU F C   1 
ATOM   6229 O O   . GLU F 3 4   ? -17.95200 19.83000  1.41100   1.000 18.34000 ? 4   GLU F O   1 
ATOM   6230 C CB  . GLU F 3 4   ? -16.18600 19.34200  -1.38400  1.000 20.79000 ? 4   GLU F CB  1 
ATOM   6231 C CG  . GLU F 3 4   ? -14.91200 18.71000  -2.01600  1.000 22.02000 ? 4   GLU F CG  1 
ATOM   6232 C CD  . GLU F 3 4   ? -14.36400 19.59900  -3.04600  1.000 54.51000 ? 4   GLU F CD  1 
ATOM   6233 O OE1 . GLU F 3 4   ? -13.72800 20.60300  -2.60400  1.000 41.09000 ? 4   GLU F OE1 1 
ATOM   6234 O OE2 . GLU F 3 4   ? -14.59400 19.30200  -4.28400  1.000 52.80000 ? 4   GLU F OE2 1 
ATOM   6235 N N   . LEU F 3 5   ? -17.46000 21.69000  0.20300   1.000 17.45000 ? 5   LEU F N   1 
ATOM   6236 C CA  . LEU F 3 5   ? -18.72400 22.38200  0.48500   1.000 16.62000 ? 5   LEU F CA  1 
ATOM   6237 C C   . LEU F 3 5   ? -19.90100 21.43000  0.33400   1.000 18.68000 ? 5   LEU F C   1 
ATOM   6238 O O   . LEU F 3 5   ? -19.96600 20.66500  -0.63500  1.000 15.37000 ? 5   LEU F O   1 
ATOM   6239 C CB  . LEU F 3 5   ? -18.92600 23.54500  -0.48900  1.000 17.44000 ? 5   LEU F CB  1 
ATOM   6240 C CG  . LEU F 3 5   ? -20.30100 24.20800  -0.44400  1.000 18.06000 ? 5   LEU F CG  1 
ATOM   6241 C CD1 . LEU F 3 5   ? -20.46500 24.82600  0.98300   1.000 15.29000 ? 5   LEU F CD1 1 
ATOM   6242 C CD2 . LEU F 3 5   ? -20.43000 25.25300  -1.55500  1.000 19.00000 ? 5   LEU F CD2 1 
ATOM   6243 N N   . HIS F 3 6   ? -20.82700 21.48200  1.31000   1.000 14.06000 ? 6   HIS F N   1 
ATOM   6244 C CA  . HIS F 3 6   ? -21.97300 20.56400  1.42700   1.000 19.86000 ? 6   HIS F CA  1 
ATOM   6245 C C   . HIS F 3 6   ? -23.25100 21.33400  1.14000   1.000 12.43000 ? 6   HIS F C   1 
ATOM   6246 O O   . HIS F 3 6   ? -23.34600 22.50100  1.55100   1.000 15.60000 ? 6   HIS F O   1 
ATOM   6247 C CB  . HIS F 3 6   ? -22.05800 19.94300  2.84900   1.000 14.02000 ? 6   HIS F CB  1 
ATOM   6248 C CG  . HIS F 3 6   ? -22.97600 18.75100  2.94000   1.000 14.89000 ? 6   HIS F CG  1 
ATOM   6249 N ND1 . HIS F 3 6   ? -24.34300 18.87000  2.94700   1.000 12.17000 ? 6   HIS F ND1 1 
ATOM   6250 C CD2 . HIS F 3 6   ? -22.70400 17.42100  3.02100   1.000 14.69000 ? 6   HIS F CD2 1 
ATOM   6251 C CE1 . HIS F 3 6   ? -24.88700 17.66000  2.97200   1.000 20.46000 ? 6   HIS F CE1 1 
ATOM   6252 N NE2 . HIS F 3 6   ? -23.90800 16.76000  3.03800   1.000 17.96000 ? 6   HIS F NE2 1 
ATOM   6253 N N   . PRO F 3 7   ? -24.20700 20.75200  0.36700   1.000 15.26000 ? 7   PRO F N   1 
ATOM   6254 C CA  . PRO F 3 7   ? -25.57400 21.34100  0.27700   1.000 15.91000 ? 7   PRO F CA  1 
ATOM   6255 C C   . PRO F 3 7   ? -26.07500 21.83100  1.62700   1.000 10.45000 ? 7   PRO F C   1 
ATOM   6256 O O   . PRO F 3 7   ? -25.75600 21.25200  2.68400   1.000 15.94000 ? 7   PRO F O   1 
ATOM   6257 C CB  . PRO F 3 7   ? -26.43900 20.17700  -0.27600  1.000 17.89000 ? 7   PRO F CB  1 
ATOM   6258 C CG  . PRO F 3 7   ? -25.38100 19.34600  -1.13400  1.000 19.41000 ? 7   PRO F CG  1 
ATOM   6259 C CD  . PRO F 3 7   ? -24.07900 19.46600  -0.34600  1.000 16.50000 ? 7   PRO F CD  1 
ATOM   6260 N N   . GLU F 3 8   ? -26.83400 22.92400  1.60800   1.000 11.29000 ? 8   GLU F N   1 
ATOM   6261 C CA  . GLU F 3 8   ? -27.42100 23.49300  2.78900   1.000 12.44000 ? 8   GLU F CA  1 
ATOM   6262 C C   . GLU F 3 8   ? -28.44900 22.52900  3.36900   1.000 16.14000 ? 8   GLU F C   1 
ATOM   6263 O O   . GLU F 3 8   ? -28.97500 21.64500  2.66700   1.000 12.21000 ? 8   GLU F O   1 
ATOM   6264 C CB  . GLU F 3 8   ? -28.07700 24.83300  2.41700   1.000 14.51000 ? 8   GLU F CB  1 
ATOM   6265 C CG  . GLU F 3 8   ? -26.94400 25.88500  2.21100   1.000 15.68000 ? 8   GLU F CG  1 
ATOM   6266 C CD  . GLU F 3 8   ? -27.16300 27.04200  1.22200   1.000 31.82000 ? 8   GLU F CD  1 
ATOM   6267 O OE1 . GLU F 3 8   ? -28.26900 27.17800  0.69000   1.000 17.25000 ? 8   GLU F OE1 1 
ATOM   6268 O OE2 . GLU F 3 8   ? -26.16600 27.83000  1.00600   1.000 22.87000 ? 8   GLU F OE2 1 
ATOM   6269 N N   . TYR F 3 9   ? -28.74100 22.71300  4.66000   1.000 13.23000 ? 9   TYR F N   1 
ATOM   6270 C CA  . TYR F 3 9   ? -29.77900 21.88100  5.34000   1.000 14.13000 ? 9   TYR F CA  1 
ATOM   6271 C C   . TYR F 3 9   ? -31.14400 22.34000  4.85400   1.000 14.32000 ? 9   TYR F C   1 
ATOM   6272 O O   . TYR F 3 9   ? -31.29600 23.42400  4.25500   1.000 13.71000 ? 9   TYR F O   1 
ATOM   6273 C CB  . TYR F 3 9   ? -29.69500 22.01500  6.90500   1.000 10.81000 ? 9   TYR F CB  1 
ATOM   6274 C CG  . TYR F 3 9   ? -28.45800 21.31400  7.49700   1.000 10.25000 ? 9   TYR F CG  1 
ATOM   6275 C CD1 . TYR F 3 9   ? -27.17000 21.79000  7.22100   1.000 10.30000 ? 9   TYR F CD1 1 
ATOM   6276 C CD2 . TYR F 3 9   ? -28.59000 20.18600  8.29300   1.000 10.96000 ? 9   TYR F CD2 1 
ATOM   6277 C CE1 . TYR F 3 9   ? -26.07500 21.16700  7.74100   1.000 10.47000 ? 9   TYR F CE1 1 
ATOM   6278 C CE2 . TYR F 3 9   ? -27.50100 19.55200  8.82600   1.000 10.23000 ? 9   TYR F CE2 1 
ATOM   6279 C CZ  . TYR F 3 9   ? -26.22300 20.05000  8.50400   1.000 12.50000 ? 9   TYR F CZ  1 
ATOM   6280 O OH  . TYR F 3 9   ? -25.11600 19.43900  9.04500   1.000 12.75000 ? 9   TYR F OH  1 
ATOM   6281 O OXT . TYR F 3 9   ? -32.13100 21.63100  5.09300   1.000 11.01000 ? 9   TYR F OXT 1 
HETATM 6282 O O   . HOH G 4 .   ? 23.74200  17.80100  33.12200  1.000 19.74000 ? 301 HOH A O   1 
HETATM 6283 O O   . HOH G 4 .   ? 23.28900  18.74600  37.54600  1.000 40.71000 ? 302 HOH A O   1 
HETATM 6284 O O   . HOH G 4 .   ? 50.04700  18.49800  57.65400  1.000 45.27000 ? 303 HOH A O   1 
HETATM 6285 O O   . HOH G 4 .   ? 3.56000   13.05400  54.09400  1.000 26.91000 ? 304 HOH A O   1 
HETATM 6286 O O   . HOH G 4 .   ? 26.47400  6.43600   60.39900  1.000 17.71000 ? 305 HOH A O   1 
HETATM 6287 O O   . HOH G 4 .   ? 22.49000  22.90200  26.36700  1.000 42.44000 ? 306 HOH A O   1 
HETATM 6288 O O   . HOH G 4 .   ? 20.55700  19.50200  77.63000  1.000 25.11000 ? 307 HOH A O   1 
HETATM 6289 O O   . HOH G 4 .   ? 42.80500  21.26600  44.32100  1.000 31.87000 ? 308 HOH A O   1 
HETATM 6290 O O   . HOH G 4 .   ? 22.73500  32.71400  21.21700  1.000 33.92000 ? 309 HOH A O   1 
HETATM 6291 O O   . HOH G 4 .   ? 12.09200  17.85900  69.59400  1.000 26.99000 ? 310 HOH A O   1 
HETATM 6292 O O   . HOH G 4 .   ? 24.96000  16.95600  74.23700  1.000 29.18000 ? 311 HOH A O   1 
HETATM 6293 O O   . HOH G 4 .   ? 27.27700  9.69800   70.26000  1.000 35.51000 ? 312 HOH A O   1 
HETATM 6294 O O   . HOH G 4 .   ? 23.83700  7.73900   68.09700  1.000 22.54000 ? 313 HOH A O   1 
HETATM 6295 O O   . HOH G 4 .   ? 14.05500  -6.03900  54.82500  1.000 33.13000 ? 314 HOH A O   1 
HETATM 6296 O O   . HOH G 4 .   ? 23.08100  23.90000  76.83700  1.000 36.06000 ? 315 HOH A O   1 
HETATM 6297 O O   . HOH G 4 .   ? 8.90500   10.91200  73.28200  1.000 28.83000 ? 316 HOH A O   1 
HETATM 6298 O O   . HOH G 4 .   ? 9.14100   -1.86600  50.03600  1.000 21.93000 ? 317 HOH A O   1 
HETATM 6299 O O   . HOH G 4 .   ? 5.37900   7.43900   50.30100  1.000 16.75000 ? 318 HOH A O   1 
HETATM 6300 O O   . HOH G 4 .   ? 21.37800  6.35700   70.33400  1.000 28.48000 ? 319 HOH A O   1 
HETATM 6301 O O   . HOH G 4 .   ? 33.07800  -3.03300  49.94400  1.000 20.04000 ? 320 HOH A O   1 
HETATM 6302 O O   . HOH G 4 .   ? 29.40300  24.99600  39.11500  1.000 17.88000 ? 321 HOH A O   1 
HETATM 6303 O O   . HOH G 4 .   ? 41.09200  26.71500  53.38800  1.000 27.68000 ? 322 HOH A O   1 
HETATM 6304 O O   . HOH G 4 .   ? 17.51700  3.59600   60.19000  1.000 16.92000 ? 323 HOH A O   1 
HETATM 6305 O O   . HOH G 4 .   ? 31.56700  8.00300   43.72000  1.000 24.74000 ? 324 HOH A O   1 
HETATM 6306 O O   . HOH G 4 .   ? 38.85700  20.48600  66.51700  1.000 31.61000 ? 325 HOH A O   1 
HETATM 6307 O O   . HOH G 4 .   ? 8.09000   -2.43000  61.80900  1.000 28.24000 ? 326 HOH A O   1 
HETATM 6308 O O   . HOH G 4 .   ? 42.24200  -2.07600  66.93300  1.000 19.69000 ? 327 HOH A O   1 
HETATM 6309 O O   . HOH G 4 .   ? 13.66800  9.81100   50.02900  1.000 12.75000 ? 328 HOH A O   1 
HETATM 6310 O O   . HOH G 4 .   ? 13.16400  -3.40900  55.00300  1.000 21.23000 ? 329 HOH A O   1 
HETATM 6311 O O   . HOH G 4 .   ? 47.59500  17.37100  51.16300  1.000 32.67000 ? 330 HOH A O   1 
HETATM 6312 O O   . HOH G 4 .   ? 25.51600  37.12200  30.57400  1.000 38.96000 ? 331 HOH A O   1 
HETATM 6313 O O   . HOH G 4 .   ? 19.25200  20.44700  60.17100  1.000 19.00000 ? 332 HOH A O   1 
HETATM 6314 O O   . HOH G 4 .   ? 45.81400  22.69100  42.57500  1.000 39.80000 ? 333 HOH A O   1 
HETATM 6315 O O   . HOH G 4 .   ? 38.56800  40.37400  33.43700  1.000 36.00000 ? 334 HOH A O   1 
HETATM 6316 O O   . HOH G 4 .   ? 33.87300  5.20100   43.84300  1.000 35.06000 ? 335 HOH A O   1 
HETATM 6317 O O   . HOH G 4 .   ? 8.17400   13.35300  73.24900  1.000 32.52000 ? 336 HOH A O   1 
HETATM 6318 O O   . HOH G 4 .   ? 26.75900  -7.68100  49.47400  1.000 22.09000 ? 337 HOH A O   1 
HETATM 6319 O O   . HOH G 4 .   ? 45.47200  26.75100  40.12100  1.000 32.94000 ? 338 HOH A O   1 
HETATM 6320 O O   . HOH G 4 .   ? 35.42600  14.67400  38.55800  1.000 16.66000 ? 339 HOH A O   1 
HETATM 6321 O O   . HOH G 4 .   ? 40.55600  24.79700  28.12100  1.000 24.08000 ? 340 HOH A O   1 
HETATM 6322 O O   . HOH G 4 .   ? 43.09400  12.22000  57.61200  1.000 27.50000 ? 341 HOH A O   1 
HETATM 6323 O O   . HOH G 4 .   ? 9.03400   -4.11200  50.49400  1.000 22.14000 ? 342 HOH A O   1 
HETATM 6324 O O   . HOH G 4 .   ? 31.60900  31.60000  40.97900  1.000 30.66000 ? 343 HOH A O   1 
HETATM 6325 O O   . HOH G 4 .   ? 22.25100  -4.87700  49.93700  1.000 15.81000 ? 344 HOH A O   1 
HETATM 6326 O O   . HOH G 4 .   ? 7.75900   18.71500  64.69900  1.000 27.07000 ? 345 HOH A O   1 
HETATM 6327 O O   . HOH G 4 .   ? 0.72700   -2.09900  58.09400  1.000 33.05000 ? 346 HOH A O   1 
HETATM 6328 O O   . HOH G 4 .   ? 13.87300  18.15300  71.71800  1.000 31.05000 ? 347 HOH A O   1 
HETATM 6329 O O   . HOH G 4 .   ? 33.39600  7.40100   57.22100  1.000 12.83000 ? 348 HOH A O   1 
HETATM 6330 O O   . HOH G 4 .   ? 44.76800  22.82400  57.41400  1.000 25.62000 ? 349 HOH A O   1 
HETATM 6331 O O   . HOH G 4 .   ? 41.73800  15.60800  47.43200  1.000 23.72000 ? 350 HOH A O   1 
HETATM 6332 O O   . HOH G 4 .   ? 1.49300   11.04800  64.91100  1.000 23.08000 ? 351 HOH A O   1 
HETATM 6333 O O   . HOH G 4 .   ? 3.99600   0.32300   49.06600  1.000 16.51000 ? 352 HOH A O   1 
HETATM 6334 O O   . HOH G 4 .   ? 5.52800   -2.46300  58.15100  1.000 23.83000 ? 353 HOH A O   1 
HETATM 6335 O O   . HOH G 4 .   ? 39.08900  29.07100  18.66100  1.000 22.59000 ? 354 HOH A O   1 
HETATM 6336 O O   . HOH G 4 .   ? 24.79300  26.81300  18.68500  1.000 32.87000 ? 355 HOH A O   1 
HETATM 6337 O O   . HOH G 4 .   ? 36.53300  5.26700   62.78500  1.000 16.14000 ? 356 HOH A O   1 
HETATM 6338 O O   . HOH G 4 .   ? 40.25800  17.32800  46.04700  1.000 27.44000 ? 357 HOH A O   1 
HETATM 6339 O O   . HOH G 4 .   ? 46.06700  15.88100  49.10800  1.000 29.42000 ? 358 HOH A O   1 
HETATM 6340 O O   . HOH G 4 .   ? 25.900    23.601    75.653    1.000 28.63000 ? 359 HOH A O   1 
HETATM 6341 O O   . HOH G 4 .   ? 36.01000  7.38800   56.25400  1.000 14.87000 ? 360 HOH A O   1 
HETATM 6342 O O   . HOH G 4 .   ? 38.18100  21.33500  49.07300  1.000 15.12000 ? 361 HOH A O   1 
HETATM 6343 O O   . HOH G 4 .   ? 30.47600  13.45700  43.15900  1.000 32.80000 ? 362 HOH A O   1 
HETATM 6344 O O   . HOH G 4 .   ? 31.10100  30.95000  63.51200  1.000 46.26000 ? 363 HOH A O   1 
HETATM 6345 O O   . HOH G 4 .   ? 7.22300   16.96700  53.34800  1.000 24.49000 ? 364 HOH A O   1 
HETATM 6346 O O   . HOH G 4 .   ? 19.75200  7.45900   60.29800  1.000 19.93000 ? 365 HOH A O   1 
HETATM 6347 O O   . HOH G 4 .   ? 19.28400  -3.55300  42.85400  1.000 39.37000 ? 366 HOH A O   1 
HETATM 6348 O O   . HOH G 4 .   ? 23.28700  15.35700  33.76900  1.000 14.18000 ? 367 HOH A O   1 
HETATM 6349 O O   . HOH G 4 .   ? -0.00800  -5.71400  50.32100  1.000 28.75000 ? 368 HOH A O   1 
HETATM 6350 O O   . HOH G 4 .   ? 38.14200  -0.72400  54.82600  1.000 29.87000 ? 369 HOH A O   1 
HETATM 6351 O O   . HOH G 4 .   ? 29.14700  38.71400  32.99600  1.000 35.35000 ? 370 HOH A O   1 
HETATM 6352 O O   . HOH G 4 .   ? 42.68500  8.10200   63.23200  1.000 38.17000 ? 371 HOH A O   1 
HETATM 6353 O O   . HOH G 4 .   ? 40.04700  16.37100  33.44000  1.000 28.50000 ? 372 HOH A O   1 
HETATM 6354 O O   . HOH G 4 .   ? 20.69300  8.76600   72.44200  1.000 28.50000 ? 373 HOH A O   1 
HETATM 6355 O O   . HOH G 4 .   ? 42.25600  29.88000  32.37400  1.000 23.45000 ? 374 HOH A O   1 
HETATM 6356 O O   . HOH G 4 .   ? 16.14300  22.42500  60.26500  1.000 33.92000 ? 375 HOH A O   1 
HETATM 6357 O O   . HOH G 4 .   ? 1.11900   11.06100  58.00000  1.000 27.45000 ? 376 HOH A O   1 
HETATM 6358 O O   . HOH G 4 .   ? 27.94300  30.43700  35.15200  1.000 28.93000 ? 377 HOH A O   1 
HETATM 6359 O O   . HOH G 4 .   ? 42.43700  31.48200  28.47500  1.000 24.92000 ? 378 HOH A O   1 
HETATM 6360 O O   . HOH G 4 .   ? -2.43800  12.02000  59.33600  1.000 35.89000 ? 379 HOH A O   1 
HETATM 6361 O O   . HOH G 4 .   ? 46.88900  16.27400  60.74100  1.000 37.88000 ? 380 HOH A O   1 
HETATM 6362 O O   . HOH G 4 .   ? 18.97100  18.21100  73.67400  1.000 34.32000 ? 381 HOH A O   1 
HETATM 6363 O O   . HOH G 4 .   ? 31.18500  34.92900  34.66500  1.000 27.79000 ? 382 HOH A O   1 
HETATM 6364 O O   . HOH G 4 .   ? 43.01000  13.11700  35.05600  1.000 27.46000 ? 383 HOH A O   1 
HETATM 6365 O O   . HOH G 4 .   ? 41.41300  18.12800  64.29100  1.000 27.70000 ? 384 HOH A O   1 
HETATM 6366 O O   . HOH G 4 .   ? 16.68100  13.77400  60.05000  1.000 16.79000 ? 385 HOH A O   1 
HETATM 6367 O O   . HOH G 4 .   ? 33.66400  -5.68600  48.33000  1.000 28.97000 ? 386 HOH A O   1 
HETATM 6368 O O   . HOH G 4 .   ? 31.99700  24.17300  44.80700  1.000 19.87000 ? 387 HOH A O   1 
HETATM 6369 O O   . HOH G 4 .   ? 35.97100  15.84700  43.30300  1.000 31.48000 ? 388 HOH A O   1 
HETATM 6370 O O   . HOH G 4 .   ? 23.68800  8.17000   49.27300  1.000 12.82000 ? 389 HOH A O   1 
HETATM 6371 O O   . HOH G 4 .   ? 10.72400  18.07900  58.45600  1.000 27.09000 ? 390 HOH A O   1 
HETATM 6372 O O   . HOH G 4 .   ? 12.94400  5.73000   71.62900  1.000 21.91000 ? 391 HOH A O   1 
HETATM 6373 O O   . HOH G 4 .   ? 31.41100  -0.86200  50.34000  1.000 14.17000 ? 392 HOH A O   1 
HETATM 6374 O O   . HOH G 4 .   ? 13.58100  -0.38300  43.89300  1.000 31.77000 ? 393 HOH A O   1 
HETATM 6375 O O   . HOH G 4 .   ? 31.84200  1.36800   65.21700  1.000 21.34000 ? 394 HOH A O   1 
HETATM 6376 O O   . HOH G 4 .   ? 27.13500  43.47600  32.15300  1.000 42.64000 ? 395 HOH A O   1 
HETATM 6377 O O   . HOH G 4 .   ? 23.06600  34.35000  2.35000   1.000 25.60000 ? 396 HOH A O   1 
HETATM 6378 O O   . HOH G 4 .   ? 34.49800  10.21500  43.63800  1.000 35.04000 ? 397 HOH A O   1 
HETATM 6379 O O   . HOH G 4 .   ? 6.80600   7.38700   68.93300  1.000 21.80000 ? 398 HOH A O   1 
HETATM 6380 O O   . HOH G 4 .   ? 32.43800  -7.13800  55.10100  1.000 32.01000 ? 399 HOH A O   1 
HETATM 6381 O O   . HOH G 4 .   ? 35.580    16.372    69.287    1.000 32.28000 ? 400 HOH A O   1 
HETATM 6382 O O   . HOH G 4 .   ? 42.99200  27.72600  47.05000  1.000 35.90000 ? 401 HOH A O   1 
HETATM 6383 O O   . HOH G 4 .   ? 11.42800  -12.90300 44.38700  1.000 20.92000 ? 402 HOH A O   1 
HETATM 6384 O O   . HOH G 4 .   ? 34.67900  28.26600  45.36800  1.000 24.92000 ? 403 HOH A O   1 
HETATM 6385 O O   . HOH G 4 .   ? 21.62600  21.50600  53.72000  1.000 45.57000 ? 404 HOH A O   1 
HETATM 6386 O O   . HOH G 4 .   ? 10.84000  17.21900  47.71500  1.000 26.15000 ? 405 HOH A O   1 
HETATM 6387 O O   . HOH G 4 .   ? 41.84400  7.31000   47.16000  1.000 36.15000 ? 406 HOH A O   1 
HETATM 6388 O O   . HOH G 4 .   ? 9.41600   20.94500  54.14700  1.000 42.60000 ? 407 HOH A O   1 
HETATM 6389 O O   . HOH G 4 .   ? 11.83300  1.81500   66.88300  1.000 21.31000 ? 408 HOH A O   1 
HETATM 6390 O O   . HOH G 4 .   ? 30.60000  18.41200  71.01500  1.000 32.77000 ? 409 HOH A O   1 
HETATM 6391 O O   . HOH G 4 .   ? 21.38000  27.65600  29.16800  1.000 31.10000 ? 410 HOH A O   1 
HETATM 6392 O O   . HOH G 4 .   ? 9.49800   1.84700   53.34000  1.000 12.21000 ? 411 HOH A O   1 
HETATM 6393 O O   . HOH G 4 .   ? 3.85600   17.81900  61.56200  1.000 28.00000 ? 412 HOH A O   1 
HETATM 6394 O O   . HOH G 4 .   ? 19.67800  6.43000   57.60800  1.000 21.02000 ? 413 HOH A O   1 
HETATM 6395 O O   . HOH G 4 .   ? 27.48200  25.41700  16.23600  1.000 36.05000 ? 414 HOH A O   1 
HETATM 6396 O O   . HOH G 4 .   ? 31.69400  42.11600  25.34100  1.000 25.97000 ? 415 HOH A O   1 
HETATM 6397 O O   . HOH G 4 .   ? 29.55300  9.92400   44.84200  1.000 28.39000 ? 416 HOH A O   1 
HETATM 6398 O O   . HOH G 4 .   ? 35.21400  28.74000  42.71300  1.000 19.91000 ? 417 HOH A O   1 
HETATM 6399 O O   . HOH G 4 .   ? 31.90400  23.30200  50.91700  1.000 29.37000 ? 418 HOH A O   1 
HETATM 6400 O O   . HOH G 4 .   ? 29.90500  24.15900  71.09000  1.000 40.16000 ? 419 HOH A O   1 
HETATM 6401 O O   . HOH G 4 .   ? 26.03400  34.59400  29.65700  1.000 27.96000 ? 420 HOH A O   1 
HETATM 6402 O O   . HOH G 4 .   ? 13.83300  12.24300  77.46000  1.000 39.52000 ? 421 HOH A O   1 
HETATM 6403 O O   . HOH G 4 .   ? 21.70100  -2.03100  63.72600  1.000 16.04000 ? 422 HOH A O   1 
HETATM 6404 O O   . HOH G 4 .   ? 13.63600  16.98800  55.96400  1.000 20.19000 ? 423 HOH A O   1 
HETATM 6405 O O   . HOH G 4 .   ? 11.04200  6.44000   46.41100  1.000 20.72000 ? 424 HOH A O   1 
HETATM 6406 O O   . HOH G 4 .   ? 13.90100  -4.73800  49.42200  1.000 13.44000 ? 425 HOH A O   1 
HETATM 6407 O O   . HOH G 4 .   ? 19.16600  6.57600   54.96100  1.000 14.65000 ? 426 HOH A O   1 
HETATM 6408 O O   . HOH G 4 .   ? 9.87000   18.00200  50.55700  1.000 26.15000 ? 427 HOH A O   1 
HETATM 6409 O O   . HOH G 4 .   ? 26.00200  -1.02800  68.08500  1.000 36.47000 ? 428 HOH A O   1 
HETATM 6410 O O   . HOH G 4 .   ? 12.36900  -8.30900  48.45400  1.000 13.26000 ? 429 HOH A O   1 
HETATM 6411 O O   . HOH G 4 .   ? 32.10100  23.64000  67.31100  1.000 30.73000 ? 430 HOH A O   1 
HETATM 6412 O O   . HOH G 4 .   ? 28.97800  1.10500   65.38700  1.000 24.05000 ? 431 HOH A O   1 
HETATM 6413 O O   . HOH G 4 .   ? 31.38200  22.04700  48.26200  1.000 28.31000 ? 432 HOH A O   1 
HETATM 6414 O O   . HOH G 4 .   ? 28.03100  2.27600   44.70900  1.000 24.96000 ? 433 HOH A O   1 
HETATM 6415 O O   . HOH G 4 .   ? 21.45200  11.52900  74.85200  1.000 30.82000 ? 434 HOH A O   1 
HETATM 6416 O O   . HOH G 4 .   ? 35.41700  38.92800  33.87800  1.000 32.54000 ? 435 HOH A O   1 
HETATM 6417 O O   . HOH G 4 .   ? 25.75600  23.67400  37.09300  1.000 18.51000 ? 436 HOH A O   1 
HETATM 6418 O O   . HOH G 4 .   ? 17.72200  -5.33700  59.24500  1.000 19.59000 ? 437 HOH A O   1 
HETATM 6419 O O   . HOH G 4 .   ? 37.46300  11.51000  45.38600  1.000 25.01000 ? 438 HOH A O   1 
HETATM 6420 O O   . HOH G 4 .   ? 35.42500  8.57400   37.12700  1.000 25.58000 ? 439 HOH A O   1 
HETATM 6421 O O   . HOH G 4 .   ? 24.68600  -4.64500  57.23600  1.000 26.31000 ? 440 HOH A O   1 
HETATM 6422 O O   . HOH G 4 .   ? 44.69700  28.34900  44.07000  1.000 38.50000 ? 441 HOH A O   1 
HETATM 6423 O O   . HOH G 4 .   ? 24.53300  24.80100  63.86200  1.000 31.89000 ? 442 HOH A O   1 
HETATM 6424 O O   . HOH G 4 .   ? 5.94000   -5.14800  58.31300  1.000 34.29000 ? 443 HOH A O   1 
HETATM 6425 O O   . HOH G 4 .   ? 24.62600  26.54300  35.33600  1.000 27.50000 ? 444 HOH A O   1 
HETATM 6426 O O   . HOH G 4 .   ? 35.27600  36.71100  21.15200  1.000 25.16000 ? 445 HOH A O   1 
HETATM 6427 O O   . HOH G 4 .   ? 40.72100  30.69800  23.27700  1.000 26.86000 ? 446 HOH A O   1 
HETATM 6428 O O   . HOH G 4 .   ? 43.20300  3.84900   62.91400  1.000 15.93000 ? 447 HOH A O   1 
HETATM 6429 O O   . HOH G 4 .   ? 20.19800  -0.94400  43.33500  1.000 32.48000 ? 448 HOH A O   1 
HETATM 6430 O O   . HOH G 4 .   ? 23.98700  -4.08300  42.70300  1.000 27.18000 ? 449 HOH A O   1 
HETATM 6431 O O   . HOH G 4 .   ? 20.84000  18.95400  71.95400  1.000 24.52000 ? 450 HOH A O   1 
HETATM 6432 O O   . HOH G 4 .   ? 49.45200  17.53200  55.33200  1.000 41.60000 ? 451 HOH A O   1 
HETATM 6433 O O   . HOH G 4 .   ? 34.51500  -3.71200  60.95700  1.000 26.67000 ? 452 HOH A O   1 
HETATM 6434 O O   . HOH G 4 .   ? 26.53400  27.59100  56.16500  1.000 41.16000 ? 453 HOH A O   1 
HETATM 6435 O O   . HOH G 4 .   ? 33.99700  25.54600  66.23400  1.000 35.31000 ? 454 HOH A O   1 
HETATM 6436 O O   . HOH G 4 .   ? 19.98800  -6.39300  57.65100  1.000 30.09000 ? 455 HOH A O   1 
HETATM 6437 O O   . HOH G 4 .   ? 24.97400  -6.36700  52.93100  1.000 26.36000 ? 456 HOH A O   1 
HETATM 6438 O O   . HOH G 4 .   ? 15.89200  14.07800  70.53800  1.000 21.03000 ? 457 HOH A O   1 
HETATM 6439 O O   . HOH G 4 .   ? -0.03300  -0.25900  59.95500  1.000 31.05000 ? 458 HOH A O   1 
HETATM 6440 O O   . HOH G 4 .   ? 11.91500  14.66200  45.38700  1.000 21.75000 ? 459 HOH A O   1 
HETATM 6441 O O   . HOH G 4 .   ? 24.38200  -0.63000  40.87900  1.000 38.50000 ? 460 HOH A O   1 
HETATM 6442 O O   . HOH G 4 .   ? 10.29400  20.28800  68.35100  1.000 38.20000 ? 461 HOH A O   1 
HETATM 6443 O O   . HOH G 4 .   ? 7.44800   0.09800   43.35600  1.000 27.57000 ? 462 HOH A O   1 
HETATM 6444 O O   . HOH G 4 .   ? 18.96700  21.28900  57.81700  1.000 34.10000 ? 463 HOH A O   1 
HETATM 6445 O O   . HOH G 4 .   ? 33.65300  23.08600  21.34700  1.000 25.70000 ? 464 HOH A O   1 
HETATM 6446 O O   . HOH G 4 .   ? 29.10900  18.62100  38.83000  1.000 21.74000 ? 465 HOH A O   1 
HETATM 6447 O O   . HOH G 4 .   ? 23.96900  37.33400  20.77900  1.000 45.84000 ? 466 HOH A O   1 
HETATM 6448 O O   . HOH G 4 .   ? 37.39500  34.74700  39.89800  1.000 29.95000 ? 467 HOH A O   1 
HETATM 6449 O O   . HOH G 4 .   ? 7.01400   13.07000  54.49200  1.000 26.78000 ? 468 HOH A O   1 
HETATM 6450 O O   . HOH G 4 .   ? 7.04900   11.09000  52.51400  1.000 26.27000 ? 469 HOH A O   1 
HETATM 6451 O O   . HOH G 4 .   ? 14.71700  19.13400  55.25900  1.000 31.31000 ? 470 HOH A O   1 
HETATM 6452 O O   . HOH G 4 .   ? 40.57800  -2.14600  58.07300  1.000 34.78000 ? 471 HOH A O   1 
HETATM 6453 O O   . HOH G 4 .   ? 20.69400  2.55000   48.16600  1.000 19.60000 ? 472 HOH A O   1 
HETATM 6454 O O   . HOH G 4 .   ? 28.72800  -11.30800 49.59500  1.000 36.50000 ? 473 HOH A O   1 
HETATM 6455 O O   . HOH G 4 .   ? 4.69800   -8.69300  48.28500  1.000 39.31000 ? 474 HOH A O   1 
HETATM 6456 O O   . HOH G 4 .   ? 5.97400   14.36300  67.75200  1.000 28.89000 ? 475 HOH A O   1 
HETATM 6457 O O   . HOH G 4 .   ? 30.28200  12.50400  69.12000  1.000 30.74000 ? 476 HOH A O   1 
HETATM 6458 O O   . HOH G 4 .   ? 5.63100   0.95600   62.22000  1.000 18.26000 ? 477 HOH A O   1 
HETATM 6459 O O   . HOH G 4 .   ? 37.11200  -2.49200  57.23700  1.000 27.06000 ? 478 HOH A O   1 
HETATM 6460 O O   . HOH G 4 .   ? 41.27600  35.53100  24.92700  1.000 35.60000 ? 479 HOH A O   1 
HETATM 6461 O O   . HOH G 4 .   ? 38.49100  -5.43700  64.14200  1.000 38.24000 ? 480 HOH A O   1 
HETATM 6462 O O   . HOH G 4 .   ? 39.33500  1.84300   48.08000  1.000 33.29000 ? 481 HOH A O   1 
HETATM 6463 O O   . HOH G 4 .   ? 42.64900  22.23500  59.33300  1.000 25.19000 ? 482 HOH A O   1 
HETATM 6464 O O   . HOH G 4 .   ? 35.25100  13.29300  44.34600  1.000 20.26000 ? 483 HOH A O   1 
HETATM 6465 O O   . HOH G 4 .   ? 4.63700   19.77200  56.14500  1.000 38.06000 ? 484 HOH A O   1 
HETATM 6466 O O   . HOH G 4 .   ? 19.15300  -7.86800  43.90300  1.000 37.06000 ? 485 HOH A O   1 
HETATM 6467 O O   . HOH G 4 .   ? 23.09500  20.81900  31.04200  1.000 20.26000 ? 486 HOH A O   1 
HETATM 6468 O O   . HOH G 4 .   ? 28.36800  24.26500  13.74800  1.000 34.12000 ? 487 HOH A O   1 
HETATM 6469 O O   . HOH G 4 .   ? 17.82400  10.31500  83.22300  1.000 46.62000 ? 488 HOH A O   1 
HETATM 6470 O O   . HOH G 4 .   ? 41.50700  38.68600  32.01900  1.000 31.29000 ? 489 HOH A O   1 
HETATM 6471 O O   . HOH G 4 .   ? 0.14100   14.50100  58.36500  1.000 27.26000 ? 490 HOH A O   1 
HETATM 6472 O O   . HOH G 4 .   ? 14.173    -10.666   54.156    1.000 37.03000 ? 491 HOH A O   1 
HETATM 6473 O O   . HOH G 4 .   ? 10.03400  22.62000  65.52700  1.000 34.41000 ? 492 HOH A O   1 
HETATM 6474 O O   . HOH G 4 .   ? 25.41200  19.17400  49.32000  1.000 32.73000 ? 493 HOH A O   1 
HETATM 6475 O O   . HOH G 4 .   ? 7.51300   1.39100   64.69200  1.000 22.22000 ? 494 HOH A O   1 
HETATM 6476 O O   . HOH G 4 .   ? 38.55700  4.15700   67.06100  1.000 39.00000 ? 495 HOH A O   1 
HETATM 6477 O O   . HOH G 4 .   ? 9.20400   13.00600  45.51300  1.000 25.77000 ? 496 HOH A O   1 
HETATM 6478 O O   . HOH G 4 .   ? 31.79800  -5.67200  44.64900  1.000 29.65000 ? 497 HOH A O   1 
HETATM 6479 O O   . HOH G 4 .   ? 37.66700  22.30300  22.10500  1.000 35.64000 ? 498 HOH A O   1 
HETATM 6480 O O   . HOH G 4 .   ? 36.93700  11.13600  67.69400  1.000 37.51000 ? 499 HOH A O   1 
HETATM 6481 O O   . HOH G 4 .   ? 23.06100  35.96800  16.26200  1.000 41.52000 ? 500 HOH A O   1 
HETATM 6482 O O   . HOH G 4 .   ? 14.16000  25.51300  67.35000  1.000 39.64000 ? 501 HOH A O   1 
HETATM 6483 O O   . HOH G 4 .   ? 33.09600  14.70100  43.20000  1.000 32.19000 ? 502 HOH A O   1 
HETATM 6484 O O   . HOH G 4 .   ? 37.62400  28.12000  51.09000  1.000 40.62000 ? 503 HOH A O   1 
HETATM 6485 O O   . HOH G 4 .   ? -1.66600  -0.35400  51.07400  1.000 20.80000 ? 504 HOH A O   1 
HETATM 6486 O O   . HOH G 4 .   ? 6.44500   6.19500   46.64800  1.000 31.53000 ? 505 HOH A O   1 
HETATM 6487 O O   . HOH G 4 .   ? 27.79300  11.77700  69.23800  1.000 30.50000 ? 506 HOH A O   1 
HETATM 6488 O O   . HOH G 4 .   ? 38.31200  18.37000  32.73700  1.000 20.54000 ? 507 HOH A O   1 
HETATM 6489 O O   . HOH G 4 .   ? 8.25700   20.57000  66.46400  1.000 38.88000 ? 508 HOH A O   1 
HETATM 6490 O O   . HOH G 4 .   ? 18.85900  6.34200   74.23100  1.000 37.87000 ? 509 HOH A O   1 
HETATM 6491 O O   . HOH G 4 .   ? 34.97500  21.88600  68.18800  1.000 35.84000 ? 510 HOH A O   1 
HETATM 6492 O O   . HOH G 4 .   ? 21.69000  19.08400  31.95300  1.000 24.05000 ? 511 HOH A O   1 
HETATM 6493 O O   . HOH G 4 .   ? 44.54600  0.95500   57.03800  1.000 32.00000 ? 512 HOH A O   1 
HETATM 6494 O O   . HOH G 4 .   ? 15.95100  25.96600  66.12800  1.000 31.55000 ? 513 HOH A O   1 
HETATM 6495 O O   . HOH G 4 .   ? 44.00600  28.25600  30.29200  1.000 27.06000 ? 514 HOH A O   1 
HETATM 6496 O O   . HOH G 4 .   ? 42.16900  35.57600  22.29300  1.000 33.15000 ? 515 HOH A O   1 
HETATM 6497 O O   . HOH G 4 .   ? 43.05500  10.70100  66.28400  1.000 46.20000 ? 516 HOH A O   1 
HETATM 6498 O O   . HOH G 4 .   ? 22.69700  25.83300  33.61400  1.000 36.78000 ? 517 HOH A O   1 
HETATM 6499 O O   . HOH G 4 .   ? 38.25400  7.83500   43.97500  1.000 38.34000 ? 518 HOH A O   1 
HETATM 6500 O O   . HOH G 4 .   ? 17.58900  -0.90500  45.57000  1.000 21.71000 ? 519 HOH A O   1 
HETATM 6501 O O   . HOH G 4 .   ? 48.08600  25.24700  37.95200  1.000 47.52000 ? 520 HOH A O   1 
HETATM 6502 O O   . HOH G 4 .   ? 23.02300  41.77300  33.81500  1.000 44.84000 ? 521 HOH A O   1 
HETATM 6503 O O   . HOH G 4 .   ? 27.84000  26.93500  37.67300  1.000 34.76000 ? 522 HOH A O   1 
HETATM 6504 O O   . HOH G 4 .   ? 14.40600  25.23800  62.54200  1.000 51.50000 ? 523 HOH A O   1 
HETATM 6505 O O   . HOH G 4 .   ? 40.40000  11.46000  45.14900  1.000 30.09000 ? 524 HOH A O   1 
HETATM 6506 O O   . HOH G 4 .   ? 3.04400   -2.06500  56.64500  1.000 37.08000 ? 525 HOH A O   1 
HETATM 6507 O O   . HOH G 4 .   ? 39.191    -1.851    69.153    1.000 41.43000 ? 526 HOH A O   1 
HETATM 6508 O O   . HOH G 4 .   ? 9.87400   -0.52700  52.16400  1.000 19.00000 ? 527 HOH A O   1 
HETATM 6509 O O   . HOH G 4 .   ? 13.96000  5.77600   73.95600  1.000 35.64000 ? 528 HOH A O   1 
HETATM 6510 O O   . HOH G 4 .   ? 19.87800  -8.92100  48.89300  1.000 24.65000 ? 529 HOH A O   1 
HETATM 6511 O O   . HOH G 4 .   ? 45.89800  27.99500  32.25200  1.000 37.06000 ? 530 HOH A O   1 
HETATM 6512 O O   . HOH G 4 .   ? -2.07800  -3.97800  58.05000  1.000 36.66000 ? 531 HOH A O   1 
HETATM 6513 O O   . HOH G 4 .   ? 44.53200  29.74500  28.39700  1.000 36.43000 ? 532 HOH A O   1 
HETATM 6514 O O   . HOH G 4 .   ? 22.29100  43.25400  24.34300  1.000 41.92000 ? 533 HOH A O   1 
HETATM 6515 O O   . HOH G 4 .   ? 19.95100  -8.32900  46.28400  1.000 22.60000 ? 534 HOH A O   1 
HETATM 6516 O O   . HOH G 4 .   ? 24.14100  28.10600  21.30100  1.000 37.56000 ? 535 HOH A O   1 
HETATM 6517 O O   . HOH G 4 .   ? 14.41900  23.21900  71.91000  1.000 45.57000 ? 536 HOH A O   1 
HETATM 6518 O O   . HOH G 4 .   ? 31.80700  -4.70200  60.87800  1.000 32.27000 ? 537 HOH A O   1 
HETATM 6519 O O   . HOH G 4 .   ? 10.26300  4.49100   44.61600  1.000 35.49000 ? 538 HOH A O   1 
HETATM 6520 O O   . HOH G 4 .   ? 11.05100  23.38800  68.24000  1.000 41.47000 ? 539 HOH A O   1 
HETATM 6521 O O   . HOH G 4 .   ? 42.78200  38.19800  34.12200  1.000 38.72000 ? 540 HOH A O   1 
HETATM 6522 O O   . HOH G 4 .   ? 35.55300  11.78300  40.40100  1.000 35.54000 ? 541 HOH A O   1 
HETATM 6523 O O   . HOH G 4 .   ? 41.127    27.368    20.974    1.000 29.42000 ? 542 HOH A O   1 
HETATM 6524 O O   . HOH G 4 .   ? 8.51600   -0.61300  65.59400  1.000 36.53000 ? 543 HOH A O   1 
HETATM 6525 O O   . HOH G 4 .   ? 47.69000  11.50000  56.83500  1.000 36.06000 ? 544 HOH A O   1 
HETATM 6526 O O   . HOH G 4 .   ? 33.33200  38.39000  35.86000  1.000 36.95000 ? 545 HOH A O   1 
HETATM 6527 O O   . HOH G 4 .   ? 8.04100   7.01200   71.39300  1.000 24.88000 ? 546 HOH A O   1 
HETATM 6528 O O   . HOH G 4 .   ? 36.68300  23.99700  48.16700  1.000 34.34000 ? 547 HOH A O   1 
HETATM 6529 O O   . HOH G 4 .   ? 4.67400   15.81000  53.37900  1.000 40.50000 ? 548 HOH A O   1 
HETATM 6530 O O   . HOH G 4 .   ? 40.86800  17.28300  42.62900  1.000 34.44000 ? 549 HOH A O   1 
HETATM 6531 O O   . HOH G 4 .   ? 25.73300  7.54500   70.01700  1.000 23.91000 ? 550 HOH A O   1 
HETATM 6532 O O   . HOH G 4 .   ? 41.937    29.215    61.225    1.000 44.48000 ? 551 HOH A O   1 
HETATM 6533 O O   . HOH G 4 .   ? 38.09200  11.15700  41.97600  1.000 36.04000 ? 552 HOH A O   1 
HETATM 6534 O O   . HOH G 4 .   ? 29.51800  23.90800  44.33800  1.000 33.78000 ? 553 HOH A O   1 
HETATM 6535 O O   . HOH G 4 .   ? 4.07300   6.50900   47.97000  1.000 26.60000 ? 554 HOH A O   1 
HETATM 6536 O O   . HOH G 4 .   ? 43.60100  18.79700  62.99300  1.000 33.06000 ? 555 HOH A O   1 
HETATM 6537 O O   . HOH G 4 .   ? 47.43900  12.31400  50.66700  1.000 38.16000 ? 556 HOH A O   1 
HETATM 6538 O O   . HOH G 4 .   ? 33.83800  31.43200  42.38900  1.000 30.92000 ? 557 HOH A O   1 
HETATM 6539 O O   . HOH G 4 .   ? 23.56000  2.75600   42.20400  1.000 32.89000 ? 558 HOH A O   1 
HETATM 6540 O O   . HOH G 4 .   ? 49.98000  15.14800  55.58600  1.000 43.58000 ? 559 HOH A O   1 
HETATM 6541 O O   . HOH G 4 .   ? 29.87600  0.10800   42.05500  1.000 44.63000 ? 560 HOH A O   1 
HETATM 6542 O O   . HOH G 4 .   ? 2.58500   12.35600  47.19600  1.000 39.40000 ? 561 HOH A O   1 
HETATM 6543 O O   . HOH G 4 .   ? 22.41400  8.77000   60.97400  1.000 20.18000 ? 562 HOH A O   1 
HETATM 6544 O O   . HOH G 4 .   ? 17.21700  28.39500  66.42100  1.000 39.86000 ? 563 HOH A O   1 
HETATM 6545 O O   . HOH G 4 .   ? 3.06700   1.47200   63.05000  1.000 27.33000 ? 564 HOH A O   1 
HETATM 6546 O O   . HOH G 4 .   ? 29.24200  19.45200  42.91300  1.000 34.40000 ? 565 HOH A O   1 
HETATM 6547 O O   . HOH G 4 .   ? 12.26900  18.72300  56.89600  1.000 33.42000 ? 566 HOH A O   1 
HETATM 6548 O O   . HOH G 4 .   ? 32.07200  -9.33000  54.43200  1.000 35.06000 ? 567 HOH A O   1 
HETATM 6549 O O   . HOH G 4 .   ? 36.42800  -4.57600  57.00000  1.000 28.71000 ? 568 HOH A O   1 
HETATM 6550 O O   . HOH G 4 .   ? 22.52800  7.82200   73.94700  1.000 36.82000 ? 569 HOH A O   1 
HETATM 6551 O O   . HOH G 4 .   ? 5.43600   -1.64400  61.62800  1.000 29.89000 ? 570 HOH A O   1 
HETATM 6552 O O   . HOH G 4 .   ? 43.72300  15.91700  38.00700  1.000 44.49000 ? 571 HOH A O   1 
HETATM 6553 O O   . HOH G 4 .   ? -0.81300  8.11400   57.01500  1.000 35.65000 ? 572 HOH A O   1 
HETATM 6554 O O   . HOH G 4 .   ? 28.29200  23.26900  40.81000  1.000 30.67000 ? 573 HOH A O   1 
HETATM 6555 O O   . HOH G 4 .   ? 23.42500  -2.76500  65.64000  1.000 27.99000 ? 574 HOH A O   1 
HETATM 6556 O O   . HOH G 4 .   ? 41.196    -3.930    68.372    1.000 25.02000 ? 575 HOH A O   1 
HETATM 6557 O O   . HOH G 4 .   ? 33.85600  9.54600   39.32100  1.000 35.37000 ? 576 HOH A O   1 
HETATM 6558 O O   . HOH G 4 .   ? 22.71200  38.72100  17.34100  1.000 40.62000 ? 577 HOH A O   1 
HETATM 6559 O O   . HOH G 4 .   ? 14.66300  4.70900   69.66300  1.000 34.62000 ? 578 HOH A O   1 
HETATM 6560 O O   . HOH G 4 .   ? 14.92200  15.64300  72.31700  1.000 30.93000 ? 579 HOH A O   1 
HETATM 6561 O O   . HOH G 4 .   ? 42.10300  -0.91700  57.06500  1.000 32.44000 ? 580 HOH A O   1 
HETATM 6562 O O   . HOH G 4 .   ? 40.88100  0.37300   54.17000  1.000 38.85000 ? 581 HOH A O   1 
HETATM 6563 O O   . HOH G 4 .   ? 33.58700  24.37500  48.18500  1.000 36.44000 ? 582 HOH A O   1 
HETATM 6564 O O   . HOH G 4 .   ? 11.53500  -2.74700  52.87600  1.000 25.85000 ? 583 HOH A O   1 
HETATM 6565 O O   . HOH G 4 .   ? -2.76500  0.49700   60.00100  1.000 32.64000 ? 584 HOH A O   1 
HETATM 6566 O O   . HOH G 4 .   ? 19.61100  5.08300   71.83500  1.000 34.57000 ? 585 HOH A O   1 
HETATM 6567 O O   . HOH G 4 .   ? 4.84900   9.77600   51.79400  1.000 30.61000 ? 586 HOH A O   1 
HETATM 6568 O O   . HOH G 4 .   ? 29.42600  8.70500   71.02900  1.000 33.33000 ? 587 HOH A O   1 
HETATM 6569 O O   . HOH G 4 .   ? 7.50800   7.77700   45.47200  1.000 37.85000 ? 588 HOH A O   1 
HETATM 6570 O O   . HOH G 4 .   ? 42.06300  32.20000  25.65400  1.000 38.23000 ? 589 HOH A O   1 
HETATM 6571 O O   . HOH G 4 .   ? 6.552     -8.352    46.279    1.000 34.73000 ? 590 HOH A O   1 
HETATM 6572 O O   . HOH G 4 .   ? 28.56300  20.46400  40.67400  1.000 33.52000 ? 591 HOH A O   1 
HETATM 6573 O O   . HOH G 4 .   ? 23.80800  6.60000   71.91700  1.000 32.91000 ? 592 HOH A O   1 
HETATM 6574 O O   . HOH G 4 .   ? 26.04600  -4.85200  54.71000  1.000 28.91000 ? 593 HOH A O   1 
HETATM 6575 O O   . HOH G 4 .   ? 11.51200  -4.93800  50.76300  1.000 23.44000 ? 594 HOH A O   1 
HETATM 6576 O O   . HOH G 4 .   ? 41.95000  13.55300  45.75600  1.000 38.47000 ? 595 HOH A O   1 
HETATM 6577 O O   . HOH G 4 .   ? 33.93000  14.34400  40.83600  1.000 25.70000 ? 596 HOH A O   1 
HETATM 6578 O O   . HOH G 4 .   ? 29.72500  22.06700  13.93600  1.000 43.01000 ? 597 HOH A O   1 
HETATM 6579 O O   . HOH G 4 .   ? 33.00100  26.09200  46.29000  1.000 23.15000 ? 598 HOH A O   1 
HETATM 6580 O O   . HOH G 4 .   ? 44.865    41.696    32.344    1.000 41.48000 ? 599 HOH A O   1 
HETATM 6581 O O   . HOH G 4 .   ? 27.97700  -7.52300  55.26300  1.000 35.77000 ? 600 HOH A O   1 
HETATM 6582 O O   . HOH G 4 .   ? 8.735     -12.576   44.684    1.000 30.61000 ? 601 HOH A O   1 
HETATM 6583 O O   . HOH G 4 .   ? 10.00000  5.24000   72.09800  1.000 29.82000 ? 602 HOH A O   1 
HETATM 6584 O O   . HOH G 4 .   ? 44.21700  31.31900  33.08900  1.000 24.20000 ? 603 HOH A O   1 
HETATM 6585 O O   . HOH G 4 .   ? 43.74000  33.69800  29.38600  1.000 32.68000 ? 604 HOH A O   1 
HETATM 6586 O O   . HOH G 4 .   ? 42.13800  19.83400  41.74900  1.000 37.60000 ? 605 HOH A O   1 
HETATM 6587 O O   . HOH G 4 .   ? 6.42600   4.46400   68.64500  1.000 30.60000 ? 606 HOH A O   1 
HETATM 6588 O O   . HOH G 4 .   ? 8.85100   3.28800   70.50300  1.000 34.39000 ? 607 HOH A O   1 
HETATM 6589 O O   . HOH G 4 .   ? 40.56400  24.33800  59.17300  1.000 36.90000 ? 608 HOH A O   1 
HETATM 6590 O O   . HOH G 4 .   ? 41.68600  8.80900   67.00500  1.000 43.98000 ? 609 HOH A O   1 
HETATM 6591 O O   . HOH G 4 .   ? 9.40700   5.21100   74.48900  1.000 38.12000 ? 610 HOH A O   1 
HETATM 6592 O O   . HOH G 4 .   ? 8.35700   6.91800   75.95100  1.000 42.68000 ? 611 HOH A O   1 
HETATM 6593 O O   . HOH G 4 .   ? 46.48000  15.67300  37.53500  1.000 49.68000 ? 612 HOH A O   1 
HETATM 6594 O O   . HOH H 4 .   ? 24.58000  -2.35400  16.58000  1.000 39.05000 ? 101 HOH B O   1 
HETATM 6595 O O   . HOH H 4 .   ? 24.81800  17.53800  39.29800  1.000 28.99000 ? 102 HOH B O   1 
HETATM 6596 O O   . HOH H 4 .   ? 6.57500   7.70300   36.51200  1.000 28.42000 ? 103 HOH B O   1 
HETATM 6597 O O   . HOH H 4 .   ? 35.01000  -0.00800  14.95800  1.000 31.85000 ? 104 HOH B O   1 
HETATM 6598 O O   . HOH H 4 .   ? 37.24000  0.98100   17.87100  1.000 30.57000 ? 105 HOH B O   1 
HETATM 6599 O O   . HOH H 4 .   ? 35.22700  0.73700   26.56400  1.000 27.74000 ? 106 HOH B O   1 
HETATM 6600 O O   . HOH H 4 .   ? 10.66000  3.94900   30.05500  1.000 32.46000 ? 107 HOH B O   1 
HETATM 6601 O O   . HOH H 4 .   ? 41.91800  5.84600   29.28200  1.000 36.01000 ? 108 HOH B O   1 
HETATM 6602 O O   . HOH H 4 .   ? 30.75100  6.73400   11.83800  1.000 36.80000 ? 109 HOH B O   1 
HETATM 6603 O O   . HOH H 4 .   ? 36.56000  4.09100   19.24000  1.000 22.33000 ? 110 HOH B O   1 
HETATM 6604 O O   . HOH H 4 .   ? 6.35500   5.62400   23.95100  1.000 23.29000 ? 111 HOH B O   1 
HETATM 6605 O O   . HOH H 4 .   ? 17.40100  19.05300  40.74500  1.000 22.01000 ? 112 HOH B O   1 
HETATM 6606 O O   . HOH H 4 .   ? 14.21700  5.17300   22.71900  1.000 30.07000 ? 113 HOH B O   1 
HETATM 6607 O O   . HOH H 4 .   ? 7.05100   4.50100   33.79200  1.000 19.48000 ? 114 HOH B O   1 
HETATM 6608 O O   . HOH H 4 .   ? 18.91400  1.17400   22.03400  1.000 37.41000 ? 115 HOH B O   1 
HETATM 6609 O O   . HOH H 4 .   ? 25.97500  17.58200  18.48800  1.000 36.99000 ? 116 HOH B O   1 
HETATM 6610 O O   . HOH H 4 .   ? 48.08000  14.91100  23.80300  1.000 24.57000 ? 117 HOH B O   1 
HETATM 6611 O O   . HOH H 4 .   ? 27.90200  12.77700  17.58100  1.000 25.90000 ? 118 HOH B O   1 
HETATM 6612 O O   . HOH H 4 .   ? 15.68100  17.67600  38.67400  1.000 26.31000 ? 119 HOH B O   1 
HETATM 6613 O O   . HOH H 4 .   ? 42.76900  10.86500  27.28900  1.000 23.05000 ? 120 HOH B O   1 
HETATM 6614 O O   . HOH H 4 .   ? 39.27600  14.66700  16.85900  1.000 24.61000 ? 121 HOH B O   1 
HETATM 6615 O O   . HOH H 4 .   ? 18.46700  2.60300   43.13800  1.000 18.06000 ? 122 HOH B O   1 
HETATM 6616 O O   . HOH H 4 .   ? 46.51100  6.05600   24.19500  1.000 30.60000 ? 123 HOH B O   1 
HETATM 6617 O O   . HOH H 4 .   ? 14.95400  5.19100   44.86500  1.000 14.73000 ? 124 HOH B O   1 
HETATM 6618 O O   . HOH H 4 .   ? 13.17200  4.49800   37.51600  1.000 16.86000 ? 125 HOH B O   1 
HETATM 6619 O O   . HOH H 4 .   ? 36.83600  1.13000   31.66500  1.000 30.11000 ? 126 HOH B O   1 
HETATM 6620 O O   . HOH H 4 .   ? 27.43600  -2.01400  15.30800  1.000 39.77000 ? 127 HOH B O   1 
HETATM 6621 O O   . HOH H 4 .   ? 48.98000  13.78400  20.62700  1.000 16.11000 ? 128 HOH B O   1 
HETATM 6622 O O   . HOH H 4 .   ? 36.50100  2.23500   34.83900  1.000 45.17000 ? 129 HOH B O   1 
HETATM 6623 O O   . HOH H 4 .   ? 36.98500  -1.59500  38.55600  1.000 50.93000 ? 130 HOH B O   1 
HETATM 6624 O O   . HOH H 4 .   ? 41.77800  7.39900   35.82900  1.000 35.29000 ? 131 HOH B O   1 
HETATM 6625 O O   . HOH H 4 .   ? 7.07800   11.64000  33.36600  1.000 21.14000 ? 132 HOH B O   1 
HETATM 6626 O O   . HOH H 4 .   ? 21.38700  0.62600   19.53200  1.000 36.95000 ? 133 HOH B O   1 
HETATM 6627 O O   . HOH H 4 .   ? 12.51600  9.45900   25.85800  1.000 30.57000 ? 134 HOH B O   1 
HETATM 6628 O O   . HOH H 4 .   ? 43.89000  15.18000  24.63900  1.000 28.60000 ? 135 HOH B O   1 
HETATM 6629 O O   . HOH H 4 .   ? 29.31800  19.70600  16.97400  1.000 38.86000 ? 136 HOH B O   1 
HETATM 6630 O O   . HOH H 4 .   ? 35.52900  9.27600   34.23700  1.000 17.78000 ? 137 HOH B O   1 
HETATM 6631 O O   . HOH H 4 .   ? 29.00000  15.25200  23.61100  1.000 17.40000 ? 138 HOH B O   1 
HETATM 6632 O O   . HOH H 4 .   ? 42.73300  10.76500  33.53600  1.000 31.09000 ? 139 HOH B O   1 
HETATM 6633 O O   . HOH H 4 .   ? 45.945    14.059    18.056    1.000 14.47000 ? 140 HOH B O   1 
HETATM 6634 O O   . HOH H 4 .   ? 16.54800  15.53300  30.59300  1.000 29.35000 ? 141 HOH B O   1 
HETATM 6635 O O   . HOH H 4 .   ? 22.13600  13.02600  20.78400  1.000 21.74000 ? 142 HOH B O   1 
HETATM 6636 O O   . HOH H 4 .   ? 22.84300  20.41100  46.36400  1.000 32.92000 ? 143 HOH B O   1 
HETATM 6637 O O   . HOH H 4 .   ? 27.29000  9.72300   42.21500  1.000 17.21000 ? 144 HOH B O   1 
HETATM 6638 O O   . HOH H 4 .   ? 15.24900  12.28200  31.07400  1.000 16.99000 ? 145 HOH B O   1 
HETATM 6639 O O   . HOH H 4 .   ? 13.05600  18.61100  46.80800  1.000 23.36000 ? 146 HOH B O   1 
HETATM 6640 O O   . HOH H 4 .   ? 34.95600  7.63000   18.12300  1.000 17.52000 ? 147 HOH B O   1 
HETATM 6641 O O   . HOH H 4 .   ? 15.99400  -0.84600  43.61900  1.000 26.70000 ? 148 HOH B O   1 
HETATM 6642 O O   . HOH H 4 .   ? 40.49400  7.28500   13.52400  1.000 29.69000 ? 149 HOH B O   1 
HETATM 6643 O O   . HOH H 4 .   ? 45.87000  8.74400   26.64200  1.000 25.82000 ? 150 HOH B O   1 
HETATM 6644 O O   . HOH H 4 .   ? 22.84600  16.39500  26.66500  1.000 33.25000 ? 151 HOH B O   1 
HETATM 6645 O O   . HOH H 4 .   ? 25.39500  16.75200  47.03400  1.000 22.52000 ? 152 HOH B O   1 
HETATM 6646 O O   . HOH H 4 .   ? 41.68700  17.08300  19.93100  1.000 38.58000 ? 153 HOH B O   1 
HETATM 6647 O O   . HOH H 4 .   ? 40.805    8.547     10.545    1.000 34.11000 ? 154 HOH B O   1 
HETATM 6648 O O   . HOH H 4 .   ? 16.32800  9.16900   22.27600  1.000 24.74000 ? 155 HOH B O   1 
HETATM 6649 O O   . HOH H 4 .   ? 12.93300  18.75100  39.17900  1.000 33.20000 ? 156 HOH B O   1 
HETATM 6650 O O   . HOH H 4 .   ? 14.22700  15.06700  44.56900  1.000 17.87000 ? 157 HOH B O   1 
HETATM 6651 O O   . HOH H 4 .   ? 34.59000  16.78400  27.31800  1.000 18.75000 ? 158 HOH B O   1 
HETATM 6652 O O   . HOH H 4 .   ? 9.05900   10.53000  27.96900  1.000 23.95000 ? 159 HOH B O   1 
HETATM 6653 O O   . HOH H 4 .   ? 34.53900  -3.15700  19.53600  1.000 37.75000 ? 160 HOH B O   1 
HETATM 6654 O O   . HOH H 4 .   ? 20.94300  16.12600  41.44100  1.000 13.61000 ? 161 HOH B O   1 
HETATM 6655 O O   . HOH H 4 .   ? 16.06300  15.25600  27.01900  1.000 37.12000 ? 162 HOH B O   1 
HETATM 6656 O O   . HOH H 4 .   ? 26.34600  15.17500  23.36900  1.000 21.04000 ? 163 HOH B O   1 
HETATM 6657 O O   . HOH H 4 .   ? 46.07700  11.27800  17.67100  1.000 18.90000 ? 164 HOH B O   1 
HETATM 6658 O O   . HOH H 4 .   ? 38.36100  1.64100   23.07600  1.000 25.08000 ? 165 HOH B O   1 
HETATM 6659 O O   . HOH H 4 .   ? 20.02400  18.47000  40.03100  1.000 19.13000 ? 166 HOH B O   1 
HETATM 6660 O O   . HOH H 4 .   ? 36.05100  1.23800   22.40900  1.000 28.98000 ? 167 HOH B O   1 
HETATM 6661 O O   . HOH H 4 .   ? 14.04500  3.62000   43.16400  1.000 29.48000 ? 168 HOH B O   1 
HETATM 6662 O O   . HOH H 4 .   ? 15.55000  20.22800  50.60700  1.000 34.77000 ? 169 HOH B O   1 
HETATM 6663 O O   . HOH H 4 .   ? 37.56000  5.06900   12.59300  1.000 30.49000 ? 170 HOH B O   1 
HETATM 6664 O O   . HOH H 4 .   ? 20.43700  -2.54200  30.09000  1.000 45.46000 ? 171 HOH B O   1 
HETATM 6665 O O   . HOH H 4 .   ? 31.67900  -1.69000  17.05400  1.000 22.15000 ? 172 HOH B O   1 
HETATM 6666 O O   . HOH H 4 .   ? 19.36100  16.13700  29.55200  1.000 27.24000 ? 173 HOH B O   1 
HETATM 6667 O O   . HOH H 4 .   ? 41.01100  2.72200   26.20500  1.000 35.68000 ? 174 HOH B O   1 
HETATM 6668 O O   . HOH H 4 .   ? 26.80200  -0.17600  29.20000  1.000 19.46000 ? 175 HOH B O   1 
HETATM 6669 O O   . HOH H 4 .   ? 26.04000  0.08200   31.90800  1.000 28.96000 ? 176 HOH B O   1 
HETATM 6670 O O   . HOH H 4 .   ? 6.47700   10.95900  36.22600  1.000 18.70000 ? 177 HOH B O   1 
HETATM 6671 O O   . HOH H 4 .   ? 39.02800  17.98100  29.87400  1.000 27.73000 ? 178 HOH B O   1 
HETATM 6672 O O   . HOH H 4 .   ? 29.94600  9.52900   18.72800  1.000 18.63000 ? 179 HOH B O   1 
HETATM 6673 O O   . HOH H 4 .   ? 32.26800  13.31700  17.96700  1.000 21.00000 ? 180 HOH B O   1 
HETATM 6674 O O   . HOH H 4 .   ? 26.83100  8.58600   18.17700  1.000 22.30000 ? 181 HOH B O   1 
HETATM 6675 O O   . HOH H 4 .   ? 41.46700  10.78400  23.41900  1.000 16.37000 ? 182 HOH B O   1 
HETATM 6676 O O   . HOH H 4 .   ? 31.87800  17.25600  16.40400  1.000 31.25000 ? 183 HOH B O   1 
HETATM 6677 O O   . HOH H 4 .   ? 10.15300  9.95300   43.27400  1.000 23.72000 ? 184 HOH B O   1 
HETATM 6678 O O   . HOH H 4 .   ? 28.86300  16.19400  40.22500  1.000 25.39000 ? 185 HOH B O   1 
HETATM 6679 O O   . HOH H 4 .   ? 26.47100  4.02100   19.64900  1.000 16.70000 ? 186 HOH B O   1 
HETATM 6680 O O   . HOH H 4 .   ? 35.14400  11.97700  13.20700  1.000 24.66000 ? 187 HOH B O   1 
HETATM 6681 O O   . HOH H 4 .   ? 26.08500  3.49300   43.52300  1.000 20.02000 ? 188 HOH B O   1 
HETATM 6682 O O   . HOH H 4 .   ? 30.31500  -2.46800  19.49800  1.000 28.89000 ? 189 HOH B O   1 
HETATM 6683 O O   . HOH H 4 .   ? 11.33600  16.09900  35.76800  1.000 24.19000 ? 190 HOH B O   1 
HETATM 6684 O O   . HOH H 4 .   ? 22.20100  -2.01100  31.96100  1.000 40.61000 ? 191 HOH B O   1 
HETATM 6685 O O   . HOH H 4 .   ? 23.92800  -4.46300  22.72100  1.000 30.18000 ? 192 HOH B O   1 
HETATM 6686 O O   . HOH H 4 .   ? 25.65800  15.51400  26.04600  1.000 14.13000 ? 193 HOH B O   1 
HETATM 6687 O O   . HOH H 4 .   ? 32.21100  -4.17200  25.55700  1.000 32.40000 ? 194 HOH B O   1 
HETATM 6688 O O   . HOH H 4 .   ? 36.325    18.163    16.442    1.000 39.99000 ? 195 HOH B O   1 
HETATM 6689 O O   . HOH H 4 .   ? 21.42800  -3.43900  24.60200  1.000 41.55000 ? 196 HOH B O   1 
HETATM 6690 O O   . HOH H 4 .   ? 36.38500  15.48200  23.33800  1.000 23.26000 ? 197 HOH B O   1 
HETATM 6691 O O   . HOH H 4 .   ? 19.69600  1.82600   28.90100  1.000 24.00000 ? 198 HOH B O   1 
HETATM 6692 O O   . HOH H 4 .   ? 22.15900  -1.95500  22.38200  1.000 32.17000 ? 199 HOH B O   1 
HETATM 6693 O O   . HOH H 4 .   ? 19.78000  10.36400  19.67500  1.000 34.25000 ? 200 HOH B O   1 
HETATM 6694 O O   . HOH H 4 .   ? 33.09500  15.35900  24.85500  1.000 16.27000 ? 201 HOH B O   1 
HETATM 6695 O O   . HOH H 4 .   ? 38.79800  6.29400   36.43800  1.000 35.14000 ? 202 HOH B O   1 
HETATM 6696 O O   . HOH H 4 .   ? 22.49200  0.67800   34.36400  1.000 26.84000 ? 203 HOH B O   1 
HETATM 6697 O O   . HOH H 4 .   ? 30.74400  0.50900   39.33300  1.000 27.73000 ? 204 HOH B O   1 
HETATM 6698 O O   . HOH H 4 .   ? 26.40900  18.53600  26.98100  1.000 25.80000 ? 205 HOH B O   1 
HETATM 6699 O O   . HOH H 4 .   ? 6.42000   14.44700  39.25200  1.000 33.53000 ? 206 HOH B O   1 
HETATM 6700 O O   . HOH H 4 .   ? 13.81300  1.99800   33.58200  1.000 34.53000 ? 207 HOH B O   1 
HETATM 6701 O O   . HOH H 4 .   ? 7.99600   15.56700  42.72700  1.000 38.41000 ? 208 HOH B O   1 
HETATM 6702 O O   . HOH H 4 .   ? 24.84900  18.13900  44.90600  1.000 30.62000 ? 209 HOH B O   1 
HETATM 6703 O O   . HOH H 4 .   ? 15.11100  17.31900  34.56200  1.000 33.53000 ? 210 HOH B O   1 
HETATM 6704 O O   . HOH H 4 .   ? 19.55000  1.77500   39.45500  1.000 27.56000 ? 211 HOH B O   1 
HETATM 6705 O O   . HOH H 4 .   ? 8.56100   7.69500   43.00400  1.000 32.07000 ? 212 HOH B O   1 
HETATM 6706 O O   . HOH H 4 .   ? 19.45200  20.74300  44.76000  1.000 23.75000 ? 213 HOH B O   1 
HETATM 6707 O O   . HOH H 4 .   ? 33.93600  -3.60300  27.63000  1.000 33.22000 ? 214 HOH B O   1 
HETATM 6708 O O   . HOH H 4 .   ? 37.78000  12.66800  13.49600  1.000 17.31000 ? 215 HOH B O   1 
HETATM 6709 O O   . HOH H 4 .   ? 28.95300  3.23500   12.77800  1.000 49.87000 ? 216 HOH B O   1 
HETATM 6710 O O   . HOH H 4 .   ? 13.63100  9.32300   23.05800  1.000 28.24000 ? 217 HOH B O   1 
HETATM 6711 O O   . HOH H 4 .   ? 7.42300   13.76000  36.42300  1.000 35.09000 ? 218 HOH B O   1 
HETATM 6712 O O   . HOH H 4 .   ? 11.41200  2.29800   34.33900  1.000 35.15000 ? 219 HOH B O   1 
HETATM 6713 O O   . HOH H 4 .   ? 29.54500  11.56300  41.23300  1.000 38.83000 ? 220 HOH B O   1 
HETATM 6714 O O   . HOH H 4 .   ? 42.38300  6.65100   15.22800  1.000 35.06000 ? 221 HOH B O   1 
HETATM 6715 O O   . HOH H 4 .   ? 32.61700  11.36500  17.03800  1.000 35.97000 ? 222 HOH B O   1 
HETATM 6716 O O   . HOH H 4 .   ? 16.56400  -0.05600  26.38600  1.000 33.87000 ? 223 HOH B O   1 
HETATM 6717 O O   . HOH H 4 .   ? 45.78200  12.91200  31.27600  1.000 42.67000 ? 224 HOH B O   1 
HETATM 6718 O O   . HOH H 4 .   ? 37.45500  6.72400   38.17300  1.000 41.19000 ? 225 HOH B O   1 
HETATM 6719 O O   . HOH H 4 .   ? 44.896    7.845     14.589    1.000 41.28000 ? 226 HOH B O   1 
HETATM 6720 O O   . HOH H 4 .   ? 30.71600  -2.81300  22.29300  1.000 34.57000 ? 227 HOH B O   1 
HETATM 6721 O O   . HOH H 4 .   ? 17.25800  0.95800   28.41300  1.000 26.69000 ? 228 HOH B O   1 
HETATM 6722 O O   . HOH H 4 .   ? 27.74900  10.20100  16.12500  1.000 39.59000 ? 229 HOH B O   1 
HETATM 6723 O O   . HOH H 4 .   ? 11.58200  3.27800   39.53400  1.000 22.09000 ? 230 HOH B O   1 
HETATM 6724 O O   . HOH H 4 .   ? 20.09200  14.18500  22.32900  1.000 38.90000 ? 231 HOH B O   1 
HETATM 6725 O O   . HOH H 4 .   ? 42.76000  4.18400   16.27400  1.000 32.63000 ? 232 HOH B O   1 
HETATM 6726 O O   . HOH H 4 .   ? 18.11900  22.91600  45.61700  1.000 34.27000 ? 233 HOH B O   1 
HETATM 6727 O O   . HOH H 4 .   ? 34.13800  12.73600  11.42200  1.000 33.76000 ? 234 HOH B O   1 
HETATM 6728 O O   . HOH H 4 .   ? 8.96900   14.05500  34.52100  1.000 38.05000 ? 235 HOH B O   1 
HETATM 6729 O O   . HOH H 4 .   ? 30.04800  -2.62700  14.84300  1.000 37.32000 ? 236 HOH B O   1 
HETATM 6730 O O   . HOH H 4 .   ? 20.38200  2.14600   45.28800  1.000 31.04000 ? 237 HOH B O   1 
HETATM 6731 O O   . HOH H 4 .   ? 16.61400  9.66200   19.73600  1.000 40.83000 ? 238 HOH B O   1 
HETATM 6732 O O   . HOH H 4 .   ? 3.98400   11.44300  36.99800  1.000 21.09000 ? 239 HOH B O   1 
HETATM 6733 O O   . HOH H 4 .   ? 25.16900  6.19400   18.23600  1.000 27.53000 ? 240 HOH B O   1 
HETATM 6734 O O   . HOH H 4 .   ? 46.25200  11.40000  25.99500  1.000 33.22000 ? 241 HOH B O   1 
HETATM 6735 O O   . HOH H 4 .   ? 45.73300  14.28500  33.34700  1.000 42.63000 ? 242 HOH B O   1 
HETATM 6736 O O   . HOH H 4 .   ? 35.40100  -1.94600  26.97900  1.000 35.63000 ? 243 HOH B O   1 
HETATM 6737 O O   . HOH H 4 .   ? 9.33900   3.79600   40.29100  1.000 26.29000 ? 244 HOH B O   1 
HETATM 6738 O O   . HOH H 4 .   ? 31.78100  11.41700  39.92700  1.000 32.79000 ? 245 HOH B O   1 
HETATM 6739 O O   . HOH H 4 .   ? 34.18300  0.38600   24.04600  1.000 28.10000 ? 246 HOH B O   1 
HETATM 6740 O O   . HOH H 4 .   ? 47.581    9.684     15.122    1.000 39.57000 ? 247 HOH B O   1 
HETATM 6741 O O   . HOH H 4 .   ? 45.13300  12.58600  28.03400  1.000 44.76000 ? 248 HOH B O   1 
HETATM 6742 O O   . HOH H 4 .   ? 25.51500  14.40000  17.63900  1.000 36.98000 ? 249 HOH B O   1 
HETATM 6743 O O   . HOH H 4 .   ? 18.57100  15.64500  27.42400  1.000 41.15000 ? 250 HOH B O   1 
HETATM 6744 O O   . HOH H 4 .   ? 30.06100  13.98900  40.68000  1.000 31.18000 ? 251 HOH B O   1 
HETATM 6745 O O   . HOH H 4 .   ? 41.68100  2.32700   17.97100  1.000 36.99000 ? 252 HOH B O   1 
HETATM 6746 O O   . HOH H 4 .   ? 12.20300  3.78100   21.87700  1.000 29.05000 ? 253 HOH B O   1 
HETATM 6747 O O   . HOH H 4 .   ? 21.33000  21.86900  43.65400  1.000 42.99000 ? 254 HOH B O   1 
HETATM 6748 O O   . HOH H 4 .   ? 32.85200  -2.16700  23.55100  1.000 26.68000 ? 255 HOH B O   1 
HETATM 6749 O O   . HOH H 4 .   ? 21.34800  16.01600  24.37000  1.000 40.69000 ? 256 HOH B O   1 
HETATM 6750 O O   . HOH I 4 .   ? 32.70000  7.91800   66.23000  1.000 26.84000 ? 101 HOH C O   1 
HETATM 6751 O O   . HOH I 4 .   ? 22.29400  4.25300   68.51100  1.000 21.08000 ? 102 HOH C O   1 
HETATM 6752 O O   . HOH I 4 .   ? 19.44700  1.81600   65.78900  1.000 16.88000 ? 103 HOH C O   1 
HETATM 6753 O O   . HOH I 4 .   ? 27.73900  3.22100   66.47300  1.000 19.59000 ? 104 HOH C O   1 
HETATM 6754 O O   . HOH I 4 .   ? 18.40300  5.51400   61.71800  1.000 18.10000 ? 105 HOH C O   1 
HETATM 6755 O O   . HOH I 4 .   ? 31.90600  3.30700   66.77700  1.000 25.94000 ? 106 HOH C O   1 
HETATM 6756 O O   . HOH I 4 .   ? 24.16700  6.92700   61.82700  1.000 18.30000 ? 107 HOH C O   1 
HETATM 6757 O O   . HOH I 4 .   ? 16.28700  2.01700   67.19300  1.000 20.14000 ? 108 HOH C O   1 
HETATM 6758 O O   . HOH I 4 .   ? 13.95200  4.05000   67.30100  1.000 21.57000 ? 109 HOH C O   1 
HETATM 6759 O O   . HOH I 4 .   ? 30.82500  9.93100   65.43700  1.000 23.56000 ? 110 HOH C O   1 
HETATM 6760 O O   . HOH I 4 .   ? 19.67300  -0.81100  65.10000  1.000 19.06000 ? 111 HOH C O   1 
HETATM 6761 O O   . HOH I 4 .   ? 28.05700  10.16500  66.61500  1.000 18.92000 ? 112 HOH C O   1 
HETATM 6762 O O   . HOH I 4 .   ? 31.20000  8.79700   69.62600  1.000 34.40000 ? 113 HOH C O   1 
HETATM 6763 O O   . HOH I 4 .   ? 16.05800  -0.49200  67.98300  1.000 42.79000 ? 114 HOH C O   1 
HETATM 6764 O O   . HOH I 4 .   ? 20.23800  2.48800   68.34900  1.000 22.12000 ? 115 HOH C O   1 
HETATM 6765 O O   . HOH I 4 .   ? 24.26500  2.78600   69.59700  1.000 28.99000 ? 116 HOH C O   1 
HETATM 6766 O O   . HOH I 4 .   ? 19.77700  -1.96500  67.16100  1.000 30.01000 ? 117 HOH C O   1 
HETATM 6767 O O   . HOH I 4 .   ? 31.51600  2.03400   69.39200  1.000 39.50000 ? 118 HOH C O   1 
HETATM 6768 O O   . HOH I 4 .   ? 26.43900  2.59800   68.80700  1.000 34.46000 ? 119 HOH C O   1 
HETATM 6769 O O   . HOH I 4 .   ? 16.89900  4.26000   70.78000  1.000 39.49000 ? 120 HOH C O   1 
HETATM 6770 O O   . HOH I 4 .   ? 20.84500  0.00200   69.41900  1.000 36.95000 ? 121 HOH C O   1 
HETATM 6771 O O   . HOH J 4 .   ? 0.15000   18.99200  0.26000   1.000 32.42000 ? 301 HOH D O   1 
HETATM 6772 O O   . HOH J 4 .   ? -12.51200 11.38600  45.29100  1.000 27.81000 ? 302 HOH D O   1 
HETATM 6773 O O   . HOH J 4 .   ? 1.24800   15.81200  6.19800   1.000 22.49000 ? 303 HOH D O   1 
HETATM 6774 O O   . HOH J 4 .   ? -15.81600 36.71700  18.14100  1.000 29.76000 ? 304 HOH D O   1 
HETATM 6775 O O   . HOH J 4 .   ? -8.95300  34.85200  4.40800   1.000 30.83000 ? 305 HOH D O   1 
HETATM 6776 O O   . HOH J 4 .   ? -4.77000  33.12300  13.78900  1.000 41.62000 ? 306 HOH D O   1 
HETATM 6777 O O   . HOH J 4 .   ? 4.56400   13.87900  24.65700  1.000 31.21000 ? 307 HOH D O   1 
HETATM 6778 O O   . HOH J 4 .   ? -37.21300 17.74500  16.91200  1.000 25.22000 ? 308 HOH D O   1 
HETATM 6779 O O   . HOH J 4 .   ? -35.60600 8.52200   12.50500  1.000 33.90000 ? 309 HOH D O   1 
HETATM 6780 O O   . HOH J 4 .   ? -1.50700  -3.83100  27.98300  1.000 28.72000 ? 310 HOH D O   1 
HETATM 6781 O O   . HOH J 4 .   ? -24.58000 37.71000  6.50300   1.000 30.31000 ? 311 HOH D O   1 
HETATM 6782 O O   . HOH J 4 .   ? -6.04600  3.08100   22.63500  1.000 18.72000 ? 312 HOH D O   1 
HETATM 6783 O O   . HOH J 4 .   ? -9.22300  12.95100  -3.06100  1.000 36.20000 ? 313 HOH D O   1 
HETATM 6784 O O   . HOH J 4 .   ? 4.58500   10.76300  30.00000  1.000 23.86000 ? 314 HOH D O   1 
HETATM 6785 O O   . HOH J 4 .   ? -16.00500 21.33700  4.76200   1.000 15.27000 ? 315 HOH D O   1 
HETATM 6786 O O   . HOH J 4 .   ? 4.79000   18.62700  28.89800  1.000 24.60000 ? 316 HOH D O   1 
HETATM 6787 O O   . HOH J 4 .   ? -36.90200 10.93000  1.50000   1.000 25.35000 ? 317 HOH D O   1 
HETATM 6788 O O   . HOH J 4 .   ? -13.26900 -0.51100  2.92000   1.000 32.54000 ? 318 HOH D O   1 
HETATM 6789 O O   . HOH J 4 .   ? -10.69200 10.31300  22.53800  1.000 32.89000 ? 319 HOH D O   1 
HETATM 6790 O O   . HOH J 4 .   ? -25.43300 14.79900  9.02200   1.000 12.71000 ? 320 HOH D O   1 
HETATM 6791 O O   . HOH J 4 .   ? 2.20900   -6.67800  25.21400  1.000 32.28000 ? 321 HOH D O   1 
HETATM 6792 O O   . HOH J 4 .   ? -26.46500 21.48000  17.89300  1.000 11.21000 ? 322 HOH D O   1 
HETATM 6793 O O   . HOH J 4 .   ? -14.83600 9.10100   58.19600  1.000 38.57000 ? 323 HOH D O   1 
HETATM 6794 O O   . HOH J 4 .   ? -2.39300  23.23400  -8.27100  1.000 34.44000 ? 324 HOH D O   1 
HETATM 6795 O O   . HOH J 4 .   ? 2.44700   -5.67900  52.72900  1.000 28.72000 ? 325 HOH D O   1 
HETATM 6796 O O   . HOH J 4 .   ? -15.84400 5.10600   -3.51300  1.000 34.89000 ? 326 HOH D O   1 
HETATM 6797 O O   . HOH J 4 .   ? -32.43900 33.81200  10.80400  1.000 35.69000 ? 327 HOH D O   1 
HETATM 6798 O O   . HOH J 4 .   ? -24.79000 24.25400  5.86400   1.000 13.35000 ? 328 HOH D O   1 
HETATM 6799 O O   . HOH J 4 .   ? -38.90500 31.49800  8.96400   1.000 27.93000 ? 329 HOH D O   1 
HETATM 6800 O O   . HOH J 4 .   ? -14.71100 1.50800   13.57900  1.000 32.09000 ? 330 HOH D O   1 
HETATM 6801 O O   . HOH J 4 .   ? 1.47300   14.64400  16.86400  1.000 13.69000 ? 331 HOH D O   1 
HETATM 6802 O O   . HOH J 4 .   ? -5.14500  4.88800   57.35600  1.000 29.94000 ? 332 HOH D O   1 
HETATM 6803 O O   . HOH J 4 .   ? -28.19600 44.71100  17.93300  1.000 30.59000 ? 333 HOH D O   1 
HETATM 6804 O O   . HOH J 4 .   ? -7.18500  23.61200  20.38200  1.000 21.53000 ? 334 HOH D O   1 
HETATM 6805 O O   . HOH J 4 .   ? -29.38100 1.71300   1.89200   1.000 34.92000 ? 335 HOH D O   1 
HETATM 6806 O O   . HOH J 4 .   ? -8.53900  20.80300  6.99700   1.000 9.48000  ? 336 HOH D O   1 
HETATM 6807 O O   . HOH J 4 .   ? 3.03600   2.22000   38.88200  1.000 17.43000 ? 337 HOH D O   1 
HETATM 6808 O O   . HOH J 4 .   ? -2.47700  9.12100   17.16400  1.000 14.33000 ? 338 HOH D O   1 
HETATM 6809 O O   . HOH J 4 .   ? -10.87100 -4.09700  37.73400  1.000 34.47000 ? 339 HOH D O   1 
HETATM 6810 O O   . HOH J 4 .   ? -8.51400  13.93500  52.76800  1.000 34.51000 ? 340 HOH D O   1 
HETATM 6811 O O   . HOH J 4 .   ? -2.30800  8.22400   1.29700   1.000 24.76000 ? 341 HOH D O   1 
HETATM 6812 O O   . HOH J 4 .   ? -9.76800  12.63500  50.59100  1.000 28.23000 ? 342 HOH D O   1 
HETATM 6813 O O   . HOH J 4 .   ? -9.41500  1.14200   28.00700  1.000 22.88000 ? 343 HOH D O   1 
HETATM 6814 O O   . HOH J 4 .   ? -13.90300 37.49600  10.10400  1.000 26.19000 ? 344 HOH D O   1 
HETATM 6815 O O   . HOH J 4 .   ? -14.27900 15.58100  42.51100  1.000 30.34000 ? 345 HOH D O   1 
HETATM 6816 O O   . HOH J 4 .   ? -6.63600  -8.69300  49.35000  1.000 30.41000 ? 346 HOH D O   1 
HETATM 6817 O O   . HOH J 4 .   ? -4.02500  28.70200  -4.09600  1.000 22.66000 ? 347 HOH D O   1 
HETATM 6818 O O   . HOH J 4 .   ? -30.81400 36.10500  21.21300  1.000 33.02000 ? 348 HOH D O   1 
HETATM 6819 O O   . HOH J 4 .   ? -17.20200 11.59100  38.13200  1.000 36.38000 ? 349 HOH D O   1 
HETATM 6820 O O   . HOH J 4 .   ? -35.34700 31.93800  17.69500  1.000 14.95000 ? 350 HOH D O   1 
HETATM 6821 O O   . HOH J 4 .   ? -11.67900 -1.46300  29.58700  1.000 41.54000 ? 351 HOH D O   1 
HETATM 6822 O O   . HOH J 4 .   ? -31.44100 19.26300  -3.39000  1.000 19.23000 ? 352 HOH D O   1 
HETATM 6823 O O   . HOH J 4 .   ? -22.44900 20.54000  6.37300   1.000 16.00000 ? 353 HOH D O   1 
HETATM 6824 O O   . HOH J 4 .   ? -24.12900 27.22400  21.02600  1.000 15.34000 ? 354 HOH D O   1 
HETATM 6825 O O   . HOH J 4 .   ? -10.72100 -2.27300  6.16400   1.000 23.33000 ? 355 HOH D O   1 
HETATM 6826 O O   . HOH J 4 .   ? -11.44300 2.94000   1.28900   1.000 14.68000 ? 356 HOH D O   1 
HETATM 6827 O O   . HOH J 4 .   ? -5.68600  20.97200  7.28900   1.000 11.18000 ? 357 HOH D O   1 
HETATM 6828 O O   . HOH J 4 .   ? -10.21300 7.94900   28.44800  1.000 14.55000 ? 358 HOH D O   1 
HETATM 6829 O O   . HOH J 4 .   ? -36.15200 20.04000  23.18000  1.000 32.58000 ? 359 HOH D O   1 
HETATM 6830 O O   . HOH J 4 .   ? -18.16200 34.96000  11.75700  1.000 13.87000 ? 360 HOH D O   1 
HETATM 6831 O O   . HOH J 4 .   ? -5.19700  3.65400   18.93500  1.000 36.59000 ? 361 HOH D O   1 
HETATM 6832 O O   . HOH J 4 .   ? -26.37500 29.92000  21.89900  1.000 22.65000 ? 362 HOH D O   1 
HETATM 6833 O O   . HOH J 4 .   ? -15.47000 5.24000   48.09000  1.000 29.31000 ? 363 HOH D O   1 
HETATM 6834 O O   . HOH J 4 .   ? -11.56900 11.28100  63.23900  1.000 42.55000 ? 364 HOH D O   1 
HETATM 6835 O O   . HOH J 4 .   ? -31.80500 35.56700  13.61700  1.000 25.45000 ? 365 HOH D O   1 
HETATM 6836 O O   . HOH J 4 .   ? -2.10500  19.25400  18.20900  1.000 15.57000 ? 366 HOH D O   1 
HETATM 6837 O O   . HOH J 4 .   ? -13.36300 1.09500   40.23500  1.000 20.24000 ? 367 HOH D O   1 
HETATM 6838 O O   . HOH J 4 .   ? -18.40500 20.63400  4.07200   1.000 16.72000 ? 368 HOH D O   1 
HETATM 6839 O O   . HOH J 4 .   ? -1.88600  12.79100  52.61500  1.000 30.71000 ? 369 HOH D O   1 
HETATM 6840 O O   . HOH J 4 .   ? -32.52800 30.20300  21.52600  1.000 23.75000 ? 370 HOH D O   1 
HETATM 6841 O O   . HOH J 4 .   ? 7.39900   11.13900  8.64600   1.000 32.31000 ? 371 HOH D O   1 
HETATM 6842 O O   . HOH J 4 .   ? -0.04300  2.80300   14.15700  1.000 24.23000 ? 372 HOH D O   1 
HETATM 6843 O O   . HOH J 4 .   ? -28.44100 32.57200  9.73400   1.000 19.23000 ? 373 HOH D O   1 
HETATM 6844 O O   . HOH J 4 .   ? -8.25700  7.41800   22.52500  1.000 13.45000 ? 374 HOH D O   1 
HETATM 6845 O O   . HOH J 4 .   ? -7.62600  -6.09500  45.37500  1.000 20.35000 ? 375 HOH D O   1 
HETATM 6846 O O   . HOH J 4 .   ? -33.61300 17.20000  15.84400  1.000 18.48000 ? 376 HOH D O   1 
HETATM 6847 O O   . HOH J 4 .   ? -14.58700 16.65100  33.64000  1.000 17.85000 ? 377 HOH D O   1 
HETATM 6848 O O   . HOH J 4 .   ? -12.64700 10.98700  48.99100  1.000 33.67000 ? 378 HOH D O   1 
HETATM 6849 O O   . HOH J 4 .   ? -11.78900 -3.31500  3.12000   1.000 22.81000 ? 379 HOH D O   1 
HETATM 6850 O O   . HOH J 4 .   ? -22.80800 18.73200  -3.74300  1.000 25.32000 ? 380 HOH D O   1 
HETATM 6851 O O   . HOH J 4 .   ? -13.16500 8.17600   -3.76200  1.000 28.08000 ? 381 HOH D O   1 
HETATM 6852 O O   . HOH J 4 .   ? 2.84700   -0.33700  46.65800  1.000 29.21000 ? 382 HOH D O   1 
HETATM 6853 O O   . HOH J 4 .   ? -1.32900  -6.56000  36.49400  1.000 25.46000 ? 383 HOH D O   1 
HETATM 6854 O O   . HOH J 4 .   ? -37.99500 10.53200  11.97300  1.000 19.98000 ? 384 HOH D O   1 
HETATM 6855 O O   . HOH J 4 .   ? 0.19700   13.14200  42.95500  1.000 27.78000 ? 385 HOH D O   1 
HETATM 6856 O O   . HOH J 4 .   ? 2.67700   5.10200   8.18000   1.000 25.48000 ? 386 HOH D O   1 
HETATM 6857 O O   . HOH J 4 .   ? -16.48100 22.80800  16.55100  1.000 11.62000 ? 387 HOH D O   1 
HETATM 6858 O O   . HOH J 4 .   ? -22.00400 22.99600  11.30300  1.000 13.14000 ? 388 HOH D O   1 
HETATM 6859 O O   . HOH J 4 .   ? 0.41000   5.84100   6.75200   1.000 17.62000 ? 389 HOH D O   1 
HETATM 6860 O O   . HOH J 4 .   ? -36.92900 26.61700  5.91600   1.000 20.43000 ? 390 HOH D O   1 
HETATM 6861 O O   . HOH J 4 .   ? -26.42900 35.34600  13.78500  1.000 14.97000 ? 391 HOH D O   1 
HETATM 6862 O O   . HOH J 4 .   ? -22.77100 8.05800   10.38100  1.000 15.49000 ? 392 HOH D O   1 
HETATM 6863 O O   . HOH J 4 .   ? 0.05100   22.60500  -1.14400  1.000 21.76000 ? 393 HOH D O   1 
HETATM 6864 O O   . HOH J 4 .   ? 3.05600   3.53300   34.93900  1.000 16.90000 ? 394 HOH D O   1 
HETATM 6865 O O   . HOH J 4 .   ? -1.70600  23.45700  18.47500  1.000 31.11000 ? 395 HOH D O   1 
HETATM 6866 O O   . HOH J 4 .   ? -37.97400 13.48900  16.80800  1.000 16.33000 ? 396 HOH D O   1 
HETATM 6867 O O   . HOH J 4 .   ? -19.95600 18.09600  -1.66600  1.000 25.10000 ? 397 HOH D O   1 
HETATM 6868 O O   . HOH J 4 .   ? 5.39700   14.11800  14.65300  1.000 22.10000 ? 398 HOH D O   1 
HETATM 6869 O O   . HOH J 4 .   ? -10.70300 4.74100   16.03200  1.000 39.83000 ? 399 HOH D O   1 
HETATM 6870 O O   . HOH J 4 .   ? -28.75200 28.61300  21.79700  1.000 20.41000 ? 400 HOH D O   1 
HETATM 6871 O O   . HOH J 4 .   ? -3.47000  -0.32500  48.19900  1.000 19.47000 ? 401 HOH D O   1 
HETATM 6872 O O   . HOH J 4 .   ? -32.53300 30.26600  2.84100   1.000 32.18000 ? 402 HOH D O   1 
HETATM 6873 O O   . HOH J 4 .   ? -10.07100 21.61100  19.60300  1.000 26.58000 ? 403 HOH D O   1 
HETATM 6874 O O   . HOH J 4 .   ? -32.89600 32.82900  15.20900  1.000 20.12000 ? 404 HOH D O   1 
HETATM 6875 O O   . HOH J 4 .   ? -21.77600 5.56200   9.74900   1.000 28.56000 ? 405 HOH D O   1 
HETATM 6876 O O   . HOH J 4 .   ? -10.08700 31.48100  17.11900  1.000 24.94000 ? 406 HOH D O   1 
HETATM 6877 O O   . HOH J 4 .   ? -29.08500 15.19200  22.53800  1.000 20.96000 ? 407 HOH D O   1 
HETATM 6878 O O   . HOH J 4 .   ? -19.93400 -1.74800  42.95000  1.000 43.01000 ? 408 HOH D O   1 
HETATM 6879 O O   . HOH J 4 .   ? -28.39300 25.97900  20.83800  1.000 14.48000 ? 409 HOH D O   1 
HETATM 6880 O O   . HOH J 4 .   ? 5.23600   4.30800   26.37400  1.000 15.21000 ? 410 HOH D O   1 
HETATM 6881 O O   . HOH J 4 .   ? -40.01200 31.04000  11.45900  1.000 27.40000 ? 411 HOH D O   1 
HETATM 6882 O O   . HOH J 4 .   ? -12.88500 13.02900  28.46300  1.000 32.03000 ? 412 HOH D O   1 
HETATM 6883 O O   . HOH J 4 .   ? -8.80400  6.85500   16.82200  1.000 27.01000 ? 413 HOH D O   1 
HETATM 6884 O O   . HOH J 4 .   ? 2.95500   -2.90100  31.81700  1.000 28.59000 ? 414 HOH D O   1 
HETATM 6885 O O   . HOH J 4 .   ? -22.11900 22.24200  8.63600   1.000 17.41000 ? 415 HOH D O   1 
HETATM 6886 O O   . HOH J 4 .   ? -18.13100 36.59900  6.42000   1.000 30.94000 ? 416 HOH D O   1 
HETATM 6887 O O   . HOH J 4 .   ? 4.52900   2.27100   25.24000  1.000 24.58000 ? 417 HOH D O   1 
HETATM 6888 O O   . HOH J 4 .   ? -21.38800 28.61800  0.32200   1.000 14.67000 ? 418 HOH D O   1 
HETATM 6889 O O   . HOH J 4 .   ? -2.05500  27.76300  15.88000  1.000 37.56000 ? 419 HOH D O   1 
HETATM 6890 O O   . HOH J 4 .   ? 0.03700   -8.46800  28.08000  1.000 36.61000 ? 420 HOH D O   1 
HETATM 6891 O O   . HOH J 4 .   ? -34.63900 23.66400  18.51600  1.000 16.33000 ? 421 HOH D O   1 
HETATM 6892 O O   . HOH J 4 .   ? -41.28100 16.43900  6.63000   1.000 15.96000 ? 422 HOH D O   1 
HETATM 6893 O O   . HOH J 4 .   ? -28.02800 37.26200  20.39000  1.000 31.04000 ? 423 HOH D O   1 
HETATM 6894 O O   . HOH J 4 .   ? 1.74900   -5.31800  56.11500  1.000 36.96000 ? 424 HOH D O   1 
HETATM 6895 O O   . HOH J 4 .   ? -31.41500 28.69300  13.47500  1.000 10.43000 ? 425 HOH D O   1 
HETATM 6896 O O   . HOH J 4 .   ? -1.46900  28.10000  13.47200  1.000 28.81000 ? 426 HOH D O   1 
HETATM 6897 O O   . HOH J 4 .   ? 2.71100   8.18100   45.95100  1.000 28.25000 ? 427 HOH D O   1 
HETATM 6898 O O   . HOH J 4 .   ? -18.61700 37.41200  10.28600  1.000 23.06000 ? 428 HOH D O   1 
HETATM 6899 O O   . HOH J 4 .   ? -35.37600 7.55400   0.41100   1.000 36.19000 ? 429 HOH D O   1 
HETATM 6900 O O   . HOH J 4 .   ? -35.92300 12.23000  -2.26900  1.000 29.44000 ? 430 HOH D O   1 
HETATM 6901 O O   . HOH J 4 .   ? -17.45800 32.74400  5.06200   1.000 19.97000 ? 431 HOH D O   1 
HETATM 6902 O O   . HOH J 4 .   ? -0.99000  9.46200   54.27700  1.000 23.21000 ? 432 HOH D O   1 
HETATM 6903 O O   . HOH J 4 .   ? 3.28200   3.83900   48.03600  1.000 18.27000 ? 433 HOH D O   1 
HETATM 6904 O O   . HOH J 4 .   ? -14.71200 8.03100   32.92400  1.000 24.54000 ? 434 HOH D O   1 
HETATM 6905 O O   . HOH J 4 .   ? -5.17700  21.02400  20.37100  1.000 36.35000 ? 435 HOH D O   1 
HETATM 6906 O O   . HOH J 4 .   ? -5.40700  2.91900   25.28800  1.000 15.88000 ? 436 HOH D O   1 
HETATM 6907 O O   . HOH J 4 .   ? -19.18100 6.67200   42.01600  1.000 42.78000 ? 437 HOH D O   1 
HETATM 6908 O O   . HOH J 4 .   ? -1.67000  27.37400  -9.24500  1.000 37.03000 ? 438 HOH D O   1 
HETATM 6909 O O   . HOH J 4 .   ? -25.68500 6.10600   11.37200  1.000 33.00000 ? 439 HOH D O   1 
HETATM 6910 O O   . HOH J 4 .   ? -19.49500 28.62000  16.20600  1.000 16.13000 ? 440 HOH D O   1 
HETATM 6911 O O   . HOH J 4 .   ? 6.351     3.925     7.675     1.000 35.63000 ? 441 HOH D O   1 
HETATM 6912 O O   . HOH J 4 .   ? -3.83000  0.41200   8.34100   1.000 23.76000 ? 442 HOH D O   1 
HETATM 6913 O O   . HOH J 4 .   ? 7.89500   11.18600  25.40900  1.000 31.92000 ? 443 HOH D O   1 
HETATM 6914 O O   . HOH J 4 .   ? -38.85900 36.39200  13.60400  1.000 30.07000 ? 444 HOH D O   1 
HETATM 6915 O O   . HOH J 4 .   ? -31.69200 24.66600  0.23600   1.000 23.07000 ? 445 HOH D O   1 
HETATM 6916 O O   . HOH J 4 .   ? -4.33200  -3.03400  55.11500  1.000 20.00000 ? 446 HOH D O   1 
HETATM 6917 O O   . HOH J 4 .   ? -31.83800 8.08500   2.57000   1.000 31.91000 ? 447 HOH D O   1 
HETATM 6918 O O   . HOH J 4 .   ? -3.21000  17.71800  26.23200  1.000 12.86000 ? 448 HOH D O   1 
HETATM 6919 O O   . HOH J 4 .   ? -27.83400 39.15800  13.69200  1.000 15.61000 ? 449 HOH D O   1 
HETATM 6920 O O   . HOH J 4 .   ? -19.93900 36.79600  19.24300  1.000 26.26000 ? 450 HOH D O   1 
HETATM 6921 O O   . HOH J 4 .   ? -22.86800 7.90000   12.82200  1.000 36.85000 ? 451 HOH D O   1 
HETATM 6922 O O   . HOH J 4 .   ? -34.95300 8.71200   7.96000   1.000 25.09000 ? 452 HOH D O   1 
HETATM 6923 O O   . HOH J 4 .   ? 8.90000   8.36900   18.19500  1.000 47.31000 ? 453 HOH D O   1 
HETATM 6924 O O   . HOH J 4 .   ? -8.89500  -1.21000  34.85600  1.000 20.21000 ? 454 HOH D O   1 
HETATM 6925 O O   . HOH J 4 .   ? -24.41200 33.13700  3.90100   1.000 24.09000 ? 455 HOH D O   1 
HETATM 6926 O O   . HOH J 4 .   ? -39.43400 34.70900  11.25400  1.000 29.91000 ? 456 HOH D O   1 
HETATM 6927 O O   . HOH J 4 .   ? 1.55300   -4.38000  37.71400  1.000 23.17000 ? 457 HOH D O   1 
HETATM 6928 O O   . HOH J 4 .   ? -32.77400 38.94000  19.93700  1.000 31.41000 ? 458 HOH D O   1 
HETATM 6929 O O   . HOH J 4 .   ? -8.63200  13.85900  48.23400  1.000 31.89000 ? 459 HOH D O   1 
HETATM 6930 O O   . HOH J 4 .   ? -11.82500 3.99700   34.06100  1.000 26.36000 ? 460 HOH D O   1 
HETATM 6931 O O   . HOH J 4 .   ? -40.361   24.771    17.484    1.000 36.95000 ? 461 HOH D O   1 
HETATM 6932 O O   . HOH J 4 .   ? -9.52500  2.00000   13.07900  1.000 25.01000 ? 462 HOH D O   1 
HETATM 6933 O O   . HOH J 4 .   ? -7.53000  32.80700  10.64600  1.000 22.90000 ? 463 HOH D O   1 
HETATM 6934 O O   . HOH J 4 .   ? -3.89800  32.50600  9.65500   1.000 32.07000 ? 464 HOH D O   1 
HETATM 6935 O O   . HOH J 4 .   ? -28.18600 11.69300  -0.48000  1.000 22.79000 ? 465 HOH D O   1 
HETATM 6936 O O   . HOH J 4 .   ? -27.78500 12.87000  14.25400  1.000 17.29000 ? 466 HOH D O   1 
HETATM 6937 O O   . HOH J 4 .   ? -7.91200  37.42600  14.09900  1.000 26.27000 ? 467 HOH D O   1 
HETATM 6938 O O   . HOH J 4 .   ? -9.09200  8.86500   19.31600  1.000 26.26000 ? 468 HOH D O   1 
HETATM 6939 O O   . HOH J 4 .   ? -41.681   27.101    17.208    1.000 17.57000 ? 469 HOH D O   1 
HETATM 6940 O O   . HOH J 4 .   ? -40.85700 15.19200  4.00500   1.000 19.11000 ? 470 HOH D O   1 
HETATM 6941 O O   . HOH J 4 .   ? -8.45300  4.95900   -0.43300  1.000 35.32000 ? 471 HOH D O   1 
HETATM 6942 O O   . HOH J 4 .   ? -17.48400 8.48400   39.45400  1.000 26.41000 ? 472 HOH D O   1 
HETATM 6943 O O   . HOH J 4 .   ? -37.37200 12.35300  3.90300   1.000 19.23000 ? 473 HOH D O   1 
HETATM 6944 O O   . HOH J 4 .   ? -8.35800  30.38300  -0.34400  1.000 24.31000 ? 474 HOH D O   1 
HETATM 6945 O O   . HOH J 4 .   ? -30.86800 31.19100  14.09100  1.000 18.01000 ? 475 HOH D O   1 
HETATM 6946 O O   . HOH J 4 .   ? -2.87300  28.96100  6.75600   1.000 26.20000 ? 476 HOH D O   1 
HETATM 6947 O O   . HOH J 4 .   ? -9.22800  30.81400  11.27600  1.000 15.18000 ? 477 HOH D O   1 
HETATM 6948 O O   . HOH J 4 .   ? -9.32000  -6.49700  2.80100   1.000 37.66000 ? 478 HOH D O   1 
HETATM 6949 O O   . HOH J 4 .   ? 3.35100   1.87000   15.92500  1.000 37.15000 ? 479 HOH D O   1 
HETATM 6950 O O   . HOH J 4 .   ? 2.19400   26.17100  7.73600   1.000 36.88000 ? 480 HOH D O   1 
HETATM 6951 O O   . HOH J 4 .   ? -31.02800 33.04000  22.54900  1.000 19.20000 ? 481 HOH D O   1 
HETATM 6952 O O   . HOH J 4 .   ? -2.98000  15.54400  21.74100  1.000 26.06000 ? 482 HOH D O   1 
HETATM 6953 O O   . HOH J 4 .   ? -26.78600 9.40800   -3.53700  1.000 29.53000 ? 483 HOH D O   1 
HETATM 6954 O O   . HOH J 4 .   ? 1.94800   16.17300  31.29100  1.000 23.00000 ? 484 HOH D O   1 
HETATM 6955 O O   . HOH J 4 .   ? 1.47900   22.70000  24.71200  1.000 33.75000 ? 485 HOH D O   1 
HETATM 6956 O O   . HOH J 4 .   ? -32.76900 5.03600   7.79500   1.000 34.53000 ? 486 HOH D O   1 
HETATM 6957 O O   . HOH J 4 .   ? -7.78100  31.73800  13.45700  1.000 39.69000 ? 487 HOH D O   1 
HETATM 6958 O O   . HOH J 4 .   ? -6.36000  4.66800   1.50400   1.000 20.55000 ? 488 HOH D O   1 
HETATM 6959 O O   . HOH J 4 .   ? -6.70200  33.97000  2.77300   1.000 32.37000 ? 489 HOH D O   1 
HETATM 6960 O O   . HOH J 4 .   ? 2.44100   4.84800   43.91000  1.000 20.67000 ? 490 HOH D O   1 
HETATM 6961 O O   . HOH J 4 .   ? -5.24600  26.12200  -3.76400  1.000 21.33000 ? 491 HOH D O   1 
HETATM 6962 O O   . HOH J 4 .   ? -4.78900  18.23500  20.29400  1.000 15.99000 ? 492 HOH D O   1 
HETATM 6963 O O   . HOH J 4 .   ? -13.49900 10.18900  30.34100  1.000 18.67000 ? 493 HOH D O   1 
HETATM 6964 O O   . HOH J 4 .   ? -18.89300 2.77100   6.83000   1.000 22.05000 ? 494 HOH D O   1 
HETATM 6965 O O   . HOH J 4 .   ? -37.54800 9.47900   6.32000   1.000 30.67000 ? 495 HOH D O   1 
HETATM 6966 O O   . HOH J 4 .   ? -4.82900  -5.15700  36.16700  1.000 22.43000 ? 496 HOH D O   1 
HETATM 6967 O O   . HOH J 4 .   ? -16.18100 13.18400  39.63500  1.000 26.98000 ? 497 HOH D O   1 
HETATM 6968 O O   . HOH J 4 .   ? -16.95200 4.39400   39.13700  1.000 39.67000 ? 498 HOH D O   1 
HETATM 6969 O O   . HOH J 4 .   ? -13.55900 2.78900   37.88200  1.000 38.97000 ? 499 HOH D O   1 
HETATM 6970 O O   . HOH J 4 .   ? -0.16600  14.67400  32.25800  1.000 18.88000 ? 500 HOH D O   1 
HETATM 6971 O O   . HOH J 4 .   ? -3.47300  -2.52700  29.25400  1.000 19.80000 ? 501 HOH D O   1 
HETATM 6972 O O   . HOH J 4 .   ? -9.78200  14.64600  27.52800  1.000 18.22000 ? 502 HOH D O   1 
HETATM 6973 O O   . HOH J 4 .   ? -28.57000 15.93800  -8.39900  1.000 34.07000 ? 503 HOH D O   1 
HETATM 6974 O O   . HOH J 4 .   ? -39.85500 18.64800  13.17600  1.000 20.23000 ? 504 HOH D O   1 
HETATM 6975 O O   . HOH J 4 .   ? 2.70900   12.34300  43.17000  1.000 40.25000 ? 505 HOH D O   1 
HETATM 6976 O O   . HOH J 4 .   ? -5.83700  -4.25100  28.73500  1.000 39.04000 ? 506 HOH D O   1 
HETATM 6977 O O   . HOH J 4 .   ? -14.47000 0.61000   49.50500  1.000 36.77000 ? 507 HOH D O   1 
HETATM 6978 O O   . HOH J 4 .   ? 2.11500   2.60900   19.68500  1.000 39.07000 ? 508 HOH D O   1 
HETATM 6979 O O   . HOH J 4 .   ? -27.20300 11.72600  20.57700  1.000 31.31000 ? 509 HOH D O   1 
HETATM 6980 O O   . HOH J 4 .   ? 1.94400   -5.41800  35.28000  1.000 30.71000 ? 510 HOH D O   1 
HETATM 6981 O O   . HOH J 4 .   ? -4.09800  -8.30900  39.38300  1.000 38.67000 ? 511 HOH D O   1 
HETATM 6982 O O   . HOH J 4 .   ? -40.06100 12.17500  11.51600  1.000 19.61000 ? 512 HOH D O   1 
HETATM 6983 O O   . HOH J 4 .   ? -38.56600 30.93000  18.41700  1.000 18.54000 ? 513 HOH D O   1 
HETATM 6984 O O   . HOH J 4 .   ? -1.74400  -2.57000  23.21500  1.000 37.10000 ? 514 HOH D O   1 
HETATM 6985 O O   . HOH J 4 .   ? -33.39400 19.78700  16.85400  1.000 19.87000 ? 515 HOH D O   1 
HETATM 6986 O O   . HOH J 4 .   ? 6.82600   12.21400  12.53000  1.000 27.39000 ? 516 HOH D O   1 
HETATM 6987 O O   . HOH J 4 .   ? -42.56700 14.28000  7.17000   1.000 30.99000 ? 517 HOH D O   1 
HETATM 6988 O O   . HOH J 4 .   ? -42.79300 30.67300  11.50300  1.000 34.05000 ? 518 HOH D O   1 
HETATM 6989 O O   . HOH J 4 .   ? -21.85100 34.70600  4.86200   1.000 24.63000 ? 519 HOH D O   1 
HETATM 6990 O O   . HOH J 4 .   ? -11.13900 12.89200  17.59000  1.000 24.74000 ? 520 HOH D O   1 
HETATM 6991 O O   . HOH J 4 .   ? -2.40000  23.95700  26.59900  1.000 26.62000 ? 521 HOH D O   1 
HETATM 6992 O O   . HOH J 4 .   ? -15.08200 14.79200  35.73800  1.000 17.43000 ? 522 HOH D O   1 
HETATM 6993 O O   . HOH J 4 .   ? -23.81600 2.58600   -6.79100  1.000 35.61000 ? 523 HOH D O   1 
HETATM 6994 O O   . HOH J 4 .   ? -18.97600 34.06800  19.57600  1.000 32.48000 ? 524 HOH D O   1 
HETATM 6995 O O   . HOH J 4 .   ? -3.66200  -2.74300  59.34200  1.000 36.29000 ? 525 HOH D O   1 
HETATM 6996 O O   . HOH J 4 .   ? -30.88600 11.24800  13.10600  1.000 22.19000 ? 526 HOH D O   1 
HETATM 6997 O O   . HOH J 4 .   ? -12.93400 -2.48400  5.52000   1.000 35.54000 ? 527 HOH D O   1 
HETATM 6998 O O   . HOH J 4 .   ? 0.06900   10.38000  49.42200  1.000 16.75000 ? 528 HOH D O   1 
HETATM 6999 O O   . HOH J 4 .   ? -5.96700  1.95700   11.91600  1.000 21.26000 ? 529 HOH D O   1 
HETATM 7000 O O   . HOH J 4 .   ? -6.91300  32.11000  0.31600   1.000 31.64000 ? 530 HOH D O   1 
HETATM 7001 O O   . HOH J 4 .   ? -6.43200  16.81600  22.26900  1.000 33.13000 ? 531 HOH D O   1 
HETATM 7002 O O   . HOH J 4 .   ? -14.67300 -6.88200  48.23300  1.000 33.72000 ? 532 HOH D O   1 
HETATM 7003 O O   . HOH J 4 .   ? -16.22200 30.31900  19.56600  1.000 33.05000 ? 533 HOH D O   1 
HETATM 7004 O O   . HOH J 4 .   ? -26.72600 1.04100   6.95400   1.000 25.27000 ? 534 HOH D O   1 
HETATM 7005 O O   . HOH J 4 .   ? 4.84000   5.00700   36.05900  1.000 21.30000 ? 535 HOH D O   1 
HETATM 7006 O O   . HOH J 4 .   ? -16.75300 34.74700  8.08100   1.000 26.18000 ? 536 HOH D O   1 
HETATM 7007 O O   . HOH J 4 .   ? -33.32300 6.18800   4.27500   1.000 37.02000 ? 537 HOH D O   1 
HETATM 7008 O O   . HOH J 4 .   ? 1.55800   24.51800  -2.42500  1.000 14.94000 ? 538 HOH D O   1 
HETATM 7009 O O   . HOH J 4 .   ? -19.81700 7.08500   -4.72000  1.000 32.14000 ? 539 HOH D O   1 
HETATM 7010 O O   . HOH J 4 .   ? -37.18000 21.87300  19.34900  1.000 34.15000 ? 540 HOH D O   1 
HETATM 7011 O O   . HOH J 4 .   ? -27.28200 2.53700   9.66400   1.000 33.12000 ? 541 HOH D O   1 
HETATM 7012 O O   . HOH J 4 .   ? 2.18900   0.33900   43.17200  1.000 28.29000 ? 542 HOH D O   1 
HETATM 7013 O O   . HOH J 4 .   ? -37.07000 29.36500  5.50400   1.000 27.47000 ? 543 HOH D O   1 
HETATM 7014 O O   . HOH J 4 .   ? -11.84700 13.29100  47.58400  1.000 36.02000 ? 544 HOH D O   1 
HETATM 7015 O O   . HOH J 4 .   ? -23.35400 12.75400  -6.68600  1.000 32.87000 ? 545 HOH D O   1 
HETATM 7016 O O   . HOH J 4 .   ? 1.47200   -3.81400  43.28900  1.000 29.71000 ? 546 HOH D O   1 
HETATM 7017 O O   . HOH J 4 .   ? -6.69400  36.32600  11.50100  1.000 37.36000 ? 547 HOH D O   1 
HETATM 7018 O O   . HOH J 4 .   ? -7.90900  27.19200  -3.19900  1.000 29.83000 ? 548 HOH D O   1 
HETATM 7019 O O   . HOH J 4 .   ? -41.23400 15.22000  14.19400  1.000 16.59000 ? 549 HOH D O   1 
HETATM 7020 O O   . HOH J 4 .   ? -16.42500 9.55100   34.70200  1.000 30.35000 ? 550 HOH D O   1 
HETATM 7021 O O   . HOH J 4 .   ? -21.80100 40.36200  10.44400  1.000 25.79000 ? 551 HOH D O   1 
HETATM 7022 O O   . HOH J 4 .   ? -28.24700 45.00500  15.73300  1.000 31.60000 ? 552 HOH D O   1 
HETATM 7023 O O   . HOH J 4 .   ? -12.24900 41.05400  8.58700   1.000 30.35000 ? 553 HOH D O   1 
HETATM 7024 O O   . HOH J 4 .   ? -15.15700 34.33300  21.84100  1.000 38.88000 ? 554 HOH D O   1 
HETATM 7025 O O   . HOH J 4 .   ? -12.09300 6.56300   30.58200  1.000 25.65000 ? 555 HOH D O   1 
HETATM 7026 O O   . HOH J 4 .   ? -7.52400  -7.01000  0.96600   1.000 33.21000 ? 556 HOH D O   1 
HETATM 7027 O O   . HOH J 4 .   ? -0.78700  20.77500  -6.45300  1.000 39.89000 ? 557 HOH D O   1 
HETATM 7028 O O   . HOH J 4 .   ? 9.71900   8.27700   20.98900  1.000 43.70000 ? 558 HOH D O   1 
HETATM 7029 O O   . HOH J 4 .   ? -19.47500 6.84100   44.83000  1.000 47.30000 ? 559 HOH D O   1 
HETATM 7030 O O   . HOH J 4 .   ? -44.359   25.536    8.869     1.000 38.75000 ? 560 HOH D O   1 
HETATM 7031 O O   . HOH J 4 .   ? -2.04000  27.85900  21.03900  1.000 42.73000 ? 561 HOH D O   1 
HETATM 7032 O O   . HOH J 4 .   ? -38.89500 25.78000  19.43300  1.000 31.04000 ? 562 HOH D O   1 
HETATM 7033 O O   . HOH J 4 .   ? 5.73200   23.72900  1.54000   1.000 29.00000 ? 563 HOH D O   1 
HETATM 7034 O O   . HOH J 4 .   ? -17.86600 35.18600  4.23600   1.000 34.38000 ? 564 HOH D O   1 
HETATM 7035 O O   . HOH J 4 .   ? -1.23400  5.54200   19.21900  1.000 32.97000 ? 565 HOH D O   1 
HETATM 7036 O O   . HOH J 4 .   ? -14.71600 7.71800   46.51600  1.000 31.80000 ? 566 HOH D O   1 
HETATM 7037 O O   . HOH J 4 .   ? -34.61300 6.20600   7.55700   1.000 37.93000 ? 567 HOH D O   1 
HETATM 7038 O O   . HOH J 4 .   ? 1.73900   11.18100  0.63600   1.000 38.06000 ? 568 HOH D O   1 
HETATM 7039 O O   . HOH J 4 .   ? 2.08100   26.64200  3.84100   1.000 24.48000 ? 569 HOH D O   1 
HETATM 7040 O O   . HOH J 4 .   ? 1.62900   21.58600  18.13500  1.000 34.88000 ? 570 HOH D O   1 
HETATM 7041 O O   . HOH J 4 .   ? -36.27300 32.62600  20.34300  1.000 22.74000 ? 571 HOH D O   1 
HETATM 7042 O O   . HOH J 4 .   ? -9.70400  37.26300  4.18800   1.000 41.22000 ? 572 HOH D O   1 
HETATM 7043 O O   . HOH J 4 .   ? -35.48600 21.11400  17.72100  1.000 28.02000 ? 573 HOH D O   1 
HETATM 7044 O O   . HOH J 4 .   ? -7.71900  -11.04500 48.57300  1.000 40.61000 ? 574 HOH D O   1 
HETATM 7045 O O   . HOH J 4 .   ? -36.55200 29.23000  19.50000  1.000 21.08000 ? 575 HOH D O   1 
HETATM 7046 O O   . HOH J 4 .   ? 0.57300   19.38600  18.28200  1.000 26.54000 ? 576 HOH D O   1 
HETATM 7047 O O   . HOH J 4 .   ? -1.12400  19.81800  22.03900  1.000 36.27000 ? 577 HOH D O   1 
HETATM 7048 O O   . HOH J 4 .   ? -5.97300  -7.63100  46.79600  1.000 29.80000 ? 578 HOH D O   1 
HETATM 7049 O O   . HOH J 4 .   ? -10.23000 -5.48200  35.93600  1.000 45.58000 ? 579 HOH D O   1 
HETATM 7050 O O   . HOH J 4 .   ? -35.77500 26.20500  2.81400   1.000 31.86000 ? 580 HOH D O   1 
HETATM 7051 O O   . HOH J 4 .   ? -3.14000  20.06200  23.83600  1.000 32.70000 ? 581 HOH D O   1 
HETATM 7052 O O   . HOH J 4 .   ? -5.49000  -1.43800  26.51300  1.000 30.34000 ? 582 HOH D O   1 
HETATM 7053 O O   . HOH J 4 .   ? -43.41700 16.64400  14.25900  1.000 27.88000 ? 583 HOH D O   1 
HETATM 7054 O O   . HOH J 4 .   ? -3.46800  6.49900   18.83200  1.000 25.75000 ? 584 HOH D O   1 
HETATM 7055 O O   . HOH J 4 .   ? -2.11500  -1.44800  9.33000   1.000 35.88000 ? 585 HOH D O   1 
HETATM 7056 O O   . HOH J 4 .   ? -30.60900 18.90500  -6.08600  1.000 26.80000 ? 586 HOH D O   1 
HETATM 7057 O O   . HOH J 4 .   ? -10.75300 8.01700   23.57600  1.000 29.72000 ? 587 HOH D O   1 
HETATM 7058 O O   . HOH J 4 .   ? -1.71400  11.64000  -0.27300  1.000 35.63000 ? 588 HOH D O   1 
HETATM 7059 O O   . HOH J 4 .   ? 2.83000   -1.90500  43.92700  1.000 29.47000 ? 589 HOH D O   1 
HETATM 7060 O O   . HOH J 4 .   ? 6.51100   17.13800  11.62000  1.000 33.54000 ? 590 HOH D O   1 
HETATM 7061 O O   . HOH J 4 .   ? -35.33400 34.61500  22.03200  1.000 31.13000 ? 591 HOH D O   1 
HETATM 7062 O O   . HOH J 4 .   ? -3.05500  29.32000  -6.47800  1.000 28.95000 ? 592 HOH D O   1 
HETATM 7063 O O   . HOH J 4 .   ? -6.84600  0.58300   26.38100  1.000 26.96000 ? 593 HOH D O   1 
HETATM 7064 O O   . HOH J 4 .   ? -25.51300 -1.10900  7.01700   1.000 43.93000 ? 594 HOH D O   1 
HETATM 7065 O O   . HOH J 4 .   ? 4.19500   1.86200   22.78300  1.000 39.72000 ? 595 HOH D O   1 
HETATM 7066 O O   . HOH J 4 .   ? 0.72300   10.19600  52.32700  1.000 24.64000 ? 596 HOH D O   1 
HETATM 7067 O O   . HOH J 4 .   ? 7.36000   2.30800   33.99700  1.000 36.18000 ? 597 HOH D O   1 
HETATM 7068 O O   . HOH J 4 .   ? -36.00400 15.12200  17.55400  1.000 21.78000 ? 598 HOH D O   1 
HETATM 7069 O O   . HOH J 4 .   ? -22.90400 25.59700  -4.35200  1.000 34.66000 ? 599 HOH D O   1 
HETATM 7070 O O   . HOH J 4 .   ? -8.83400  16.54400  22.61700  1.000 37.88000 ? 600 HOH D O   1 
HETATM 7071 O O   . HOH J 4 .   ? -4.98400  24.18000  22.69300  1.000 31.26000 ? 601 HOH D O   1 
HETATM 7072 O O   . HOH J 4 .   ? -10.56900 31.25300  -0.00700  1.000 27.43000 ? 602 HOH D O   1 
HETATM 7073 O O   . HOH J 4 .   ? -35.03700 30.33700  21.10600  1.000 26.86000 ? 603 HOH D O   1 
HETATM 7074 O O   . HOH J 4 .   ? -20.07500 19.18600  5.73800   1.000 21.21000 ? 604 HOH D O   1 
HETATM 7075 O O   . HOH J 4 .   ? -11.37000 9.15400   26.65700  1.000 33.61000 ? 605 HOH D O   1 
HETATM 7076 O O   . HOH J 4 .   ? -6.71400  -4.93200  34.37200  1.000 25.82000 ? 606 HOH D O   1 
HETATM 7077 O O   . HOH J 4 .   ? -9.50800  -1.81000  27.28600  1.000 47.40000 ? 607 HOH D O   1 
HETATM 7078 O O   . HOH J 4 .   ? -29.28100 20.59800  -2.10100  1.000 33.51000 ? 608 HOH D O   1 
HETATM 7079 O O   . HOH J 4 .   ? 4.43900   15.06700  31.23600  1.000 29.35000 ? 609 HOH D O   1 
HETATM 7080 O O   . HOH J 4 .   ? 0.62600   7.73200   2.36700   1.000 33.70000 ? 610 HOH D O   1 
HETATM 7081 O O   . HOH J 4 .   ? -17.71900 6.03500   -4.45700  1.000 34.19000 ? 611 HOH D O   1 
HETATM 7082 O O   . HOH J 4 .   ? -27.111   38.426    9.826     1.000 31.50000 ? 612 HOH D O   1 
HETATM 7083 O O   . HOH J 4 .   ? -14.51100 24.94200  -2.06000  1.000 35.48000 ? 613 HOH D O   1 
HETATM 7084 O O   . HOH J 4 .   ? -2.85200  21.65300  20.11900  1.000 37.20000 ? 614 HOH D O   1 
HETATM 7085 O O   . HOH J 4 .   ? 1.36400   16.31800  20.86200  1.000 37.10000 ? 615 HOH D O   1 
HETATM 7086 O O   . HOH J 4 .   ? -2.26500  31.14400  8.22700   1.000 39.49000 ? 616 HOH D O   1 
HETATM 7087 O O   . HOH J 4 .   ? -7.59500  6.81200   19.34200  1.000 34.04000 ? 617 HOH D O   1 
HETATM 7088 O O   . HOH J 4 .   ? 5.63500   3.29000   37.92000  1.000 26.76000 ? 618 HOH D O   1 
HETATM 7089 O O   . HOH J 4 .   ? -17.86800 10.56700  -7.29000  1.000 38.84000 ? 619 HOH D O   1 
HETATM 7090 O O   . HOH J 4 .   ? -0.87300  20.95200  -2.97800  1.000 33.46000 ? 620 HOH D O   1 
HETATM 7091 O O   . HOH J 4 .   ? -8.20200  30.11000  -2.91700  1.000 30.80000 ? 621 HOH D O   1 
HETATM 7092 O O   . HOH J 4 .   ? -17.36300 13.32000  35.61500  1.000 26.26000 ? 622 HOH D O   1 
HETATM 7093 O O   . HOH J 4 .   ? -9.17100  2.10400   -0.47100  1.000 37.98000 ? 623 HOH D O   1 
HETATM 7094 O O   . HOH J 4 .   ? -14.35300 30.09000  20.76400  1.000 35.43000 ? 624 HOH D O   1 
HETATM 7095 O O   . HOH J 4 .   ? -0.18600  27.88500  7.14400   1.000 35.07000 ? 625 HOH D O   1 
HETATM 7096 O O   . HOH J 4 .   ? -40.24500 12.40200  3.84800   1.000 22.88000 ? 626 HOH D O   1 
HETATM 7097 O O   . HOH J 4 .   ? -6.66700  21.84300  22.47200  1.000 37.90000 ? 627 HOH D O   1 
HETATM 7098 O O   . HOH J 4 .   ? -7.88700  32.99200  15.46500  1.000 36.02000 ? 628 HOH D O   1 
HETATM 7099 O O   . HOH J 4 .   ? 2.35200   9.81800   47.94400  1.000 21.76000 ? 629 HOH D O   1 
HETATM 7100 O O   . HOH J 4 .   ? -2.68300  -5.83300  26.79200  1.000 42.38000 ? 630 HOH D O   1 
HETATM 7101 O O   . HOH J 4 .   ? -12.70500 -4.33100  0.37600   1.000 40.41000 ? 631 HOH D O   1 
HETATM 7102 O O   . HOH J 4 .   ? -4.55300  22.65500  24.62000  1.000 28.31000 ? 632 HOH D O   1 
HETATM 7103 O O   . HOH J 4 .   ? 4.79900   1.53200   34.31900  1.000 34.18000 ? 633 HOH D O   1 
HETATM 7104 O O   . HOH J 4 .   ? -8.528    -12.573   50.095    1.000 38.28000 ? 634 HOH D O   1 
HETATM 7105 O O   . HOH J 4 .   ? 3.30200   2.52800   8.32300   1.000 36.80000 ? 635 HOH D O   1 
HETATM 7106 O O   . HOH J 4 .   ? -28.99500 35.36900  12.99400  1.000 24.35000 ? 636 HOH D O   1 
HETATM 7107 O O   . HOH J 4 .   ? -15.22900 33.23500  6.62000   1.000 20.35000 ? 637 HOH D O   1 
HETATM 7108 O O   . HOH J 4 .   ? -29.99300 32.71600  11.74600  1.000 26.53000 ? 638 HOH D O   1 
HETATM 7109 O O   . HOH J 4 .   ? -28.65900 18.42400  -8.48600  1.000 51.00000 ? 639 HOH D O   1 
HETATM 7110 O O   . HOH J 4 .   ? -11.06800 -4.60800  7.29100   1.000 41.51000 ? 640 HOH D O   1 
HETATM 7111 O O   . HOH J 4 .   ? -18.84900 29.95900  18.56400  1.000 26.21000 ? 641 HOH D O   1 
HETATM 7112 O O   . HOH J 4 .   ? -7.65400  5.20500   21.20500  1.000 27.66000 ? 642 HOH D O   1 
HETATM 7113 O O   . HOH J 4 .   ? -13.36300 1.04900   0.46000   1.000 28.11000 ? 643 HOH D O   1 
HETATM 7114 O O   . HOH J 4 .   ? -41.22000 11.71400  1.45900   1.000 35.08000 ? 644 HOH D O   1 
HETATM 7115 O O   . HOH J 4 .   ? 2.25000   17.07100  17.92300  1.000 32.98000 ? 645 HOH D O   1 
HETATM 7116 O O   . HOH J 4 .   ? -14.50100 11.67900  50.77700  1.000 36.42000 ? 646 HOH D O   1 
HETATM 7117 O O   . HOH J 4 .   ? -39.42100 11.14600  0.23000   1.000 33.13000 ? 647 HOH D O   1 
HETATM 7118 O O   . HOH J 4 .   ? -1.95100  17.56600  20.51300  1.000 24.64000 ? 648 HOH D O   1 
HETATM 7119 O O   . HOH J 4 .   ? -25.34000 7.13600   13.62900  1.000 37.22000 ? 649 HOH D O   1 
HETATM 7120 O O   . HOH J 4 .   ? -27.26000 8.55800   14.62600  1.000 36.23000 ? 650 HOH D O   1 
HETATM 7121 O O   . HOH J 4 .   ? -18.14100 4.47600   36.75200  1.000 40.33000 ? 651 HOH D O   1 
HETATM 7122 O O   . HOH J 4 .   ? 2.35300   9.43400   2.49700   1.000 32.31000 ? 652 HOH D O   1 
HETATM 7123 O O   . HOH J 4 .   ? -5.04000  18.17400  24.21600  1.000 21.69000 ? 653 HOH D O   1 
HETATM 7124 O O   . HOH J 4 .   ? -23.86900 27.73500  -2.91500  1.000 39.12000 ? 654 HOH D O   1 
HETATM 7125 O O   . HOH J 4 .   ? -3.58600  1.24400   10.95800  1.000 33.31000 ? 655 HOH D O   1 
HETATM 7126 O O   . HOH J 4 .   ? 9.20300   13.82700  12.54700  1.000 39.76000 ? 656 HOH D O   1 
HETATM 7127 O O   . HOH J 4 .   ? 4.62400   12.55700  32.52300  1.000 24.73000 ? 657 HOH D O   1 
HETATM 7128 O O   . HOH J 4 .   ? -2.95400  17.16300  -3.49300  1.000 38.07000 ? 658 HOH D O   1 
HETATM 7129 O O   . HOH J 4 .   ? -26.74200 34.53200  4.77600   1.000 41.49000 ? 659 HOH D O   1 
HETATM 7130 O O   . HOH J 4 .   ? -40.37400 37.82300  14.59400  1.000 43.88000 ? 660 HOH D O   1 
HETATM 7131 O O   . HOH J 4 .   ? -10.66200 12.27000  25.78000  1.000 33.02000 ? 661 HOH D O   1 
HETATM 7132 O O   . HOH J 4 .   ? -26.480   39.190    7.489     1.000 33.08000 ? 662 HOH D O   1 
HETATM 7133 O O   . HOH J 4 .   ? -17.27900 7.13500   49.56400  1.000 34.15000 ? 663 HOH D O   1 
HETATM 7134 O O   . HOH J 4 .   ? -16.10800 10.16100  30.81500  1.000 35.84000 ? 664 HOH D O   1 
HETATM 7135 O O   . HOH J 4 .   ? -2.31400  19.12300  -1.69600  1.000 30.80000 ? 665 HOH D O   1 
HETATM 7136 O O   . HOH J 4 .   ? -10.13800 -3.89300  12.28100  1.000 27.83000 ? 666 HOH D O   1 
HETATM 7137 O O   . HOH J 4 .   ? -10.99400 -5.24600  10.03400  1.000 35.97000 ? 667 HOH D O   1 
HETATM 7138 O O   . HOH J 4 .   ? 5.03500   17.41100  18.39100  1.000 35.05000 ? 668 HOH D O   1 
HETATM 7139 O O   . HOH J 4 .   ? -15.97900 -0.70300  13.09900  1.000 32.57000 ? 669 HOH D O   1 
HETATM 7140 O O   . HOH J 4 .   ? 4.82700   20.43600  18.63300  1.000 34.99000 ? 670 HOH D O   1 
HETATM 7141 O O   . HOH J 4 .   ? 4.69800   -0.74800  32.39900  1.000 37.27000 ? 671 HOH D O   1 
HETATM 7142 O O   . HOH J 4 .   ? -17.30800 9.33100   49.24300  1.000 36.22000 ? 672 HOH D O   1 
HETATM 7143 O O   . HOH J 4 .   ? -14.81800 -3.86000  12.66200  1.000 48.28000 ? 673 HOH D O   1 
HETATM 7144 O O   . HOH J 4 .   ? -25.80300 4.88700   15.85500  1.000 44.19000 ? 674 HOH D O   1 
HETATM 7145 O O   . HOH J 4 .   ? -13.45800 -5.77000  10.55000  1.000 47.95000 ? 675 HOH D O   1 
HETATM 7146 O O   . HOH K 4 .   ? -1.27000  27.84800  23.30100  1.000 44.49000 ? 101 HOH E O   1 
HETATM 7147 O O   . HOH K 4 .   ? -18.48600 15.47400  28.79400  1.000 31.52000 ? 102 HOH E O   1 
HETATM 7148 O O   . HOH K 4 .   ? 2.80000   34.26300  43.94300  1.000 39.97000 ? 103 HOH E O   1 
HETATM 7149 O O   . HOH K 4 .   ? -20.83000 35.62100  31.32700  1.000 42.31000 ? 104 HOH E O   1 
HETATM 7150 O O   . HOH K 4 .   ? 1.55700   31.05500  43.05900  1.000 32.83000 ? 105 HOH E O   1 
HETATM 7151 O O   . HOH K 4 .   ? -19.74600 29.62100  21.29900  1.000 24.34000 ? 106 HOH E O   1 
HETATM 7152 O O   . HOH K 4 .   ? -8.02000  20.59300  41.79700  1.000 22.18000 ? 107 HOH E O   1 
HETATM 7153 O O   . HOH K 4 .   ? -20.24600 36.97700  33.71400  1.000 43.73000 ? 108 HOH E O   1 
HETATM 7154 O O   . HOH K 4 .   ? 5.86300   20.65700  39.29500  1.000 21.65000 ? 109 HOH E O   1 
HETATM 7155 O O   . HOH K 4 .   ? -0.58100  33.18500  35.26100  1.000 30.09000 ? 110 HOH E O   1 
HETATM 7156 O O   . HOH K 4 .   ? 4.05500   30.28500  50.26700  1.000 37.60000 ? 111 HOH E O   1 
HETATM 7157 O O   . HOH K 4 .   ? -28.47700 24.39200  23.31200  1.000 24.32000 ? 112 HOH E O   1 
HETATM 7158 O O   . HOH K 4 .   ? -13.84300 36.64800  31.35600  1.000 38.95000 ? 113 HOH E O   1 
HETATM 7159 O O   . HOH K 4 .   ? -7.75400  38.31600  29.45200  1.000 38.44000 ? 114 HOH E O   1 
HETATM 7160 O O   . HOH K 4 .   ? -3.99300  38.12000  42.38600  1.000 32.28000 ? 115 HOH E O   1 
HETATM 7161 O O   . HOH K 4 .   ? -8.23600  32.63400  43.74100  1.000 22.08000 ? 116 HOH E O   1 
HETATM 7162 O O   . HOH K 4 .   ? -11.69100 22.36800  22.94800  1.000 13.76000 ? 117 HOH E O   1 
HETATM 7163 O O   . HOH K 4 .   ? -0.42900  27.77400  45.15500  1.000 24.53000 ? 118 HOH E O   1 
HETATM 7164 O O   . HOH K 4 .   ? -24.11700 11.86500  27.34600  1.000 31.34000 ? 119 HOH E O   1 
HETATM 7165 O O   . HOH K 4 .   ? 8.27000   19.56700  40.13900  1.000 28.31000 ? 120 HOH E O   1 
HETATM 7166 O O   . HOH K 4 .   ? -26.81100 13.91500  23.23600  1.000 21.80000 ? 121 HOH E O   1 
HETATM 7167 O O   . HOH K 4 .   ? 1.72200   32.14500  39.44000  1.000 29.28000 ? 122 HOH E O   1 
HETATM 7168 O O   . HOH K 4 .   ? -23.14000 16.82900  29.91900  1.000 31.25000 ? 123 HOH E O   1 
HETATM 7169 O O   . HOH K 4 .   ? -0.76600  18.65800  41.61100  1.000 29.38000 ? 124 HOH E O   1 
HETATM 7170 O O   . HOH K 4 .   ? 14.38300  21.03400  42.88500  1.000 28.31000 ? 125 HOH E O   1 
HETATM 7171 O O   . HOH K 4 .   ? 5.76000   26.50400  32.89500  1.000 36.29000 ? 126 HOH E O   1 
HETATM 7172 O O   . HOH K 4 .   ? -25.60700 33.35900  46.51900  1.000 28.96000 ? 127 HOH E O   1 
HETATM 7173 O O   . HOH K 4 .   ? -21.93700 15.24700  28.66100  1.000 34.31000 ? 128 HOH E O   1 
HETATM 7174 O O   . HOH K 4 .   ? -20.79400 32.65800  43.07100  1.000 34.63000 ? 129 HOH E O   1 
HETATM 7175 O O   . HOH K 4 .   ? -24.19800 30.21600  28.27200  1.000 19.01000 ? 130 HOH E O   1 
HETATM 7176 O O   . HOH K 4 .   ? -8.15100  28.95500  20.64100  1.000 21.17000 ? 131 HOH E O   1 
HETATM 7177 O O   . HOH K 4 .   ? -24.64900 15.54000  27.33100  1.000 34.61000 ? 132 HOH E O   1 
HETATM 7178 O O   . HOH K 4 .   ? -18.23500 17.22600  26.57900  1.000 13.08000 ? 133 HOH E O   1 
HETATM 7179 O O   . HOH K 4 .   ? -14.07300 15.51300  20.39900  1.000 23.42000 ? 134 HOH E O   1 
HETATM 7180 O O   . HOH K 4 .   ? 5.68600   28.21100  49.17800  1.000 34.87000 ? 135 HOH E O   1 
HETATM 7181 O O   . HOH K 4 .   ? 5.89800   21.85200  36.55300  1.000 21.63000 ? 136 HOH E O   1 
HETATM 7182 O O   . HOH K 4 .   ? -0.02000  16.84100  48.38200  1.000 40.03000 ? 137 HOH E O   1 
HETATM 7183 O O   . HOH K 4 .   ? -2.07400  16.58300  50.84200  1.000 42.05000 ? 138 HOH E O   1 
HETATM 7184 O O   . HOH K 4 .   ? 2.78700   20.00000  46.65400  1.000 45.98000 ? 139 HOH E O   1 
HETATM 7185 O O   . HOH K 4 .   ? -14.13600 33.46900  29.24900  1.000 25.27000 ? 140 HOH E O   1 
HETATM 7186 O O   . HOH K 4 .   ? -13.81800 19.53600  40.07700  1.000 23.33000 ? 141 HOH E O   1 
HETATM 7187 O O   . HOH K 4 .   ? -10.43300 21.20600  42.70900  1.000 19.92000 ? 142 HOH E O   1 
HETATM 7188 O O   . HOH K 4 .   ? -16.13400 33.64900  34.72500  1.000 25.85000 ? 143 HOH E O   1 
HETATM 7189 O O   . HOH K 4 .   ? -20.91700 20.63400  37.21400  1.000 34.91000 ? 144 HOH E O   1 
HETATM 7190 O O   . HOH K 4 .   ? -12.39900 38.56100  40.83600  1.000 33.14000 ? 145 HOH E O   1 
HETATM 7191 O O   . HOH K 4 .   ? -10.14800 34.03100  30.92300  1.000 28.61000 ? 146 HOH E O   1 
HETATM 7192 O O   . HOH K 4 .   ? 5.05600   21.47000  30.14100  1.000 34.48000 ? 147 HOH E O   1 
HETATM 7193 O O   . HOH K 4 .   ? -13.00900 39.67300  38.10200  1.000 44.33000 ? 148 HOH E O   1 
HETATM 7194 O O   . HOH K 4 .   ? 10.34900  27.09300  38.04400  1.000 31.42000 ? 149 HOH E O   1 
HETATM 7195 O O   . HOH K 4 .   ? 5.48400   21.71300  47.05600  1.000 30.25000 ? 150 HOH E O   1 
HETATM 7196 O O   . HOH K 4 .   ? -2.26800  23.58800  29.42600  1.000 16.27000 ? 151 HOH E O   1 
HETATM 7197 O O   . HOH K 4 .   ? 1.15900   15.30000  34.96700  1.000 22.83000 ? 152 HOH E O   1 
HETATM 7198 O O   . HOH K 4 .   ? 12.59100  20.73300  45.02300  1.000 27.25000 ? 153 HOH E O   1 
HETATM 7199 O O   . HOH K 4 .   ? -4.54200  19.69400  49.01100  1.000 35.78000 ? 154 HOH E O   1 
HETATM 7200 O O   . HOH K 4 .   ? -1.81200  37.68700  44.61800  1.000 34.55000 ? 155 HOH E O   1 
HETATM 7201 O O   . HOH K 4 .   ? -1.80400  30.58500  28.55800  1.000 27.21000 ? 156 HOH E O   1 
HETATM 7202 O O   . HOH K 4 .   ? 5.88200   17.22300  39.00600  1.000 36.02000 ? 157 HOH E O   1 
HETATM 7203 O O   . HOH K 4 .   ? -10.70600 16.46800  26.05500  1.000 25.70000 ? 158 HOH E O   1 
HETATM 7204 O O   . HOH K 4 .   ? -16.97400 11.76900  22.79600  1.000 30.67000 ? 159 HOH E O   1 
HETATM 7205 O O   . HOH K 4 .   ? -17.67100 29.22700  23.38500  1.000 22.44000 ? 160 HOH E O   1 
HETATM 7206 O O   . HOH K 4 .   ? -5.35400  26.96900  45.34900  1.000 24.39000 ? 161 HOH E O   1 
HETATM 7207 O O   . HOH K 4 .   ? -2.71600  17.55600  38.02700  1.000 23.50000 ? 162 HOH E O   1 
HETATM 7208 O O   . HOH K 4 .   ? -27.13900 19.82900  32.94700  1.000 29.98000 ? 163 HOH E O   1 
HETATM 7209 O O   . HOH K 4 .   ? 9.15300   23.46700  36.45800  1.000 38.39000 ? 164 HOH E O   1 
HETATM 7210 O O   . HOH K 4 .   ? 4.45600   32.46400  42.39400  1.000 33.73000 ? 165 HOH E O   1 
HETATM 7211 O O   . HOH K 4 .   ? -14.84800 19.20300  33.02700  1.000 12.37000 ? 166 HOH E O   1 
HETATM 7212 O O   . HOH K 4 .   ? 5.27500   30.48300  36.08500  1.000 34.45000 ? 167 HOH E O   1 
HETATM 7213 O O   . HOH K 4 .   ? -29.31200 19.03700  31.47300  1.000 40.62000 ? 168 HOH E O   1 
HETATM 7214 O O   . HOH K 4 .   ? -10.84700 16.72000  39.36300  1.000 19.72000 ? 169 HOH E O   1 
HETATM 7215 O O   . HOH K 4 .   ? -10.76200 28.84100  17.75500  1.000 20.61000 ? 170 HOH E O   1 
HETATM 7216 O O   . HOH K 4 .   ? -8.86400  34.57900  33.55400  1.000 20.08000 ? 171 HOH E O   1 
HETATM 7217 O O   . HOH K 4 .   ? -1.50300  37.44700  33.45400  1.000 26.48000 ? 172 HOH E O   1 
HETATM 7218 O O   . HOH K 4 .   ? 3.63100   24.49100  26.74900  1.000 33.27000 ? 173 HOH E O   1 
HETATM 7219 O O   . HOH K 4 .   ? -12.94000 28.30000  19.43300  1.000 18.37000 ? 174 HOH E O   1 
HETATM 7220 O O   . HOH K 4 .   ? -10.44500 40.36300  39.33700  1.000 37.87000 ? 175 HOH E O   1 
HETATM 7221 O O   . HOH K 4 .   ? -17.87000 31.51300  24.91500  1.000 33.63000 ? 176 HOH E O   1 
HETATM 7222 O O   . HOH K 4 .   ? 1.09300   34.19600  39.31000  1.000 35.76000 ? 177 HOH E O   1 
HETATM 7223 O O   . HOH K 4 .   ? 4.74900   23.05400  40.06900  1.000 19.63000 ? 178 HOH E O   1 
HETATM 7224 O O   . HOH K 4 .   ? -5.01600  27.22400  22.27100  1.000 32.59000 ? 179 HOH E O   1 
HETATM 7225 O O   . HOH K 4 .   ? -32.11200 20.22100  28.32200  1.000 35.42000 ? 180 HOH E O   1 
HETATM 7226 O O   . HOH K 4 .   ? -2.76600  38.63300  35.66000  1.000 25.96000 ? 181 HOH E O   1 
HETATM 7227 O O   . HOH K 4 .   ? -23.88500 29.40300  22.35400  1.000 26.82000 ? 182 HOH E O   1 
HETATM 7228 O O   . HOH K 4 .   ? -20.13400 12.04800  24.61700  1.000 20.00000 ? 183 HOH E O   1 
HETATM 7229 O O   . HOH K 4 .   ? -17.99000 19.64100  37.84200  1.000 22.40000 ? 184 HOH E O   1 
HETATM 7230 O O   . HOH K 4 .   ? 11.18600  25.05500  44.05300  1.000 38.24000 ? 185 HOH E O   1 
HETATM 7231 O O   . HOH K 4 .   ? -24.89800 10.86300  20.63100  1.000 34.96000 ? 186 HOH E O   1 
HETATM 7232 O O   . HOH K 4 .   ? 8.91400   23.13300  47.17500  1.000 35.52000 ? 187 HOH E O   1 
HETATM 7233 O O   . HOH K 4 .   ? 0.26700   38.44200  42.32800  1.000 40.82000 ? 188 HOH E O   1 
HETATM 7234 O O   . HOH K 4 .   ? -23.28100 28.18400  40.57900  1.000 30.33000 ? 189 HOH E O   1 
HETATM 7235 O O   . HOH K 4 .   ? -3.76400  19.49200  40.11400  1.000 19.04000 ? 190 HOH E O   1 
HETATM 7236 O O   . HOH K 4 .   ? -11.32500 20.30000  40.11000  1.000 16.39000 ? 191 HOH E O   1 
HETATM 7237 O O   . HOH K 4 .   ? -15.99700 35.89300  42.23600  1.000 32.17000 ? 192 HOH E O   1 
HETATM 7238 O O   . HOH K 4 .   ? 4.82200   15.37200  34.50400  1.000 32.59000 ? 193 HOH E O   1 
HETATM 7239 O O   . HOH K 4 .   ? -6.68500  31.66500  23.45500  1.000 21.48000 ? 194 HOH E O   1 
HETATM 7240 O O   . HOH K 4 .   ? -22.93400 33.49300  20.48200  1.000 26.29000 ? 195 HOH E O   1 
HETATM 7241 O O   . HOH K 4 .   ? -0.32100  16.54100  37.43200  1.000 32.22000 ? 196 HOH E O   1 
HETATM 7242 O O   . HOH K 4 .   ? -3.39000  23.08900  46.58600  1.000 39.04000 ? 197 HOH E O   1 
HETATM 7243 O O   . HOH K 4 .   ? 3.74400   30.36100  53.13500  1.000 40.26000 ? 198 HOH E O   1 
HETATM 7244 O O   . HOH K 4 .   ? 1.20500   25.72100  26.42300  1.000 36.41000 ? 199 HOH E O   1 
HETATM 7245 O O   . HOH K 4 .   ? -12.00400 14.67300  19.84000  1.000 31.81000 ? 200 HOH E O   1 
HETATM 7246 O O   . HOH K 4 .   ? -2.58400  25.34900  46.54100  1.000 42.32000 ? 201 HOH E O   1 
HETATM 7247 O O   . HOH K 4 .   ? -3.94300  38.19700  38.79600  1.000 38.41000 ? 202 HOH E O   1 
HETATM 7248 O O   . HOH K 4 .   ? -26.92000 23.99000  37.10300  1.000 44.37000 ? 203 HOH E O   1 
HETATM 7249 O O   . HOH K 4 .   ? -9.46200  33.40900  28.25900  1.000 32.37000 ? 204 HOH E O   1 
HETATM 7250 O O   . HOH K 4 .   ? -22.06900 28.68300  43.05600  1.000 32.86000 ? 205 HOH E O   1 
HETATM 7251 O O   . HOH K 4 .   ? -25.69200 23.27900  38.88200  1.000 41.57000 ? 206 HOH E O   1 
HETATM 7252 O O   . HOH K 4 .   ? -19.31300 13.35300  26.98700  1.000 35.56000 ? 207 HOH E O   1 
HETATM 7253 O O   . HOH K 4 .   ? 8.10300   19.40400  32.74400  1.000 44.26000 ? 208 HOH E O   1 
HETATM 7254 O O   . HOH K 4 .   ? 13.21200  25.51400  42.31200  1.000 42.31000 ? 209 HOH E O   1 
HETATM 7255 O O   . HOH K 4 .   ? -18.18100 36.74700  37.32400  1.000 32.10000 ? 210 HOH E O   1 
HETATM 7256 O O   . HOH K 4 .   ? 7.46500   29.02800  46.97400  1.000 39.68000 ? 211 HOH E O   1 
HETATM 7257 O O   . HOH K 4 .   ? -11.87300 14.55700  24.02800  1.000 34.69000 ? 212 HOH E O   1 
HETATM 7258 O O   . HOH K 4 .   ? 5.63900   23.64600  32.52900  1.000 34.50000 ? 213 HOH E O   1 
HETATM 7259 O O   . HOH K 4 .   ? -7.84200  31.49200  20.99400  1.000 31.81000 ? 214 HOH E O   1 
HETATM 7260 O O   . HOH K 4 .   ? -1.50300  16.53900  39.96200  1.000 31.84000 ? 215 HOH E O   1 
HETATM 7261 O O   . HOH K 4 .   ? -8.85800  20.23800  24.76200  1.000 33.46000 ? 216 HOH E O   1 
HETATM 7262 O O   . HOH K 4 .   ? -13.382   32.891    45.960    1.000 39.77000 ? 217 HOH E O   1 
HETATM 7263 O O   . HOH K 4 .   ? 7.55900   19.88500  35.29000  1.000 29.10000 ? 218 HOH E O   1 
HETATM 7264 O O   . HOH K 4 .   ? 15.37000  23.42600  44.13200  1.000 37.79000 ? 219 HOH E O   1 
HETATM 7265 O O   . HOH K 4 .   ? -20.18200 31.93200  18.97200  1.000 30.04000 ? 220 HOH E O   1 
HETATM 7266 O O   . HOH K 4 .   ? 7.38300   17.48300  36.23500  1.000 36.63000 ? 221 HOH E O   1 
HETATM 7267 O O   . HOH K 4 .   ? -25.98900 31.18800  26.39500  1.000 21.38000 ? 222 HOH E O   1 
HETATM 7268 O O   . HOH K 4 .   ? 16.98800  21.57200  39.26200  1.000 39.72000 ? 223 HOH E O   1 
HETATM 7269 O O   . HOH K 4 .   ? -13.16700 16.73500  40.12100  1.000 25.16000 ? 224 HOH E O   1 
HETATM 7270 O O   . HOH K 4 .   ? 9.65500   21.04100  38.32900  1.000 39.46000 ? 225 HOH E O   1 
HETATM 7271 O O   . HOH K 4 .   ? 0.23400   35.67400  34.40500  1.000 33.42000 ? 226 HOH E O   1 
HETATM 7272 O O   . HOH K 4 .   ? -9.16000  17.88000  25.04900  1.000 24.14000 ? 227 HOH E O   1 
HETATM 7273 O O   . HOH K 4 .   ? -15.09200 15.68600  38.34700  1.000 24.41000 ? 228 HOH E O   1 
HETATM 7274 O O   . HOH K 4 .   ? -0.91700  34.59300  37.55100  1.000 30.73000 ? 229 HOH E O   1 
HETATM 7275 O O   . HOH K 4 .   ? 3.48200   13.54700  34.99000  1.000 25.92000 ? 230 HOH E O   1 
HETATM 7276 O O   . HOH K 4 .   ? -1.89700  37.05800  37.92500  1.000 31.23000 ? 231 HOH E O   1 
HETATM 7277 O O   . HOH L 4 .   ? -30.46300 26.56500  1.15200   1.000 19.61000 ? 101 HOH F O   1 
HETATM 7278 O O   . HOH L 4 .   ? -11.72700 20.59700  -3.82400  1.000 62.30000 ? 102 HOH F O   1 
HETATM 7279 O O   . HOH L 4 .   ? -21.64700 21.06000  -2.70400  1.000 23.98000 ? 103 HOH F O   1 
HETATM 7280 O O   . HOH L 4 .   ? -12.752   16.665    0.242     1.000 27.34000 ? 104 HOH F O   1 
HETATM 7281 O O   . HOH L 4 .   ? -28.23100 26.65200  -1.98400  1.000 36.67000 ? 105 HOH F O   1 
HETATM 7282 O O   . HOH L 4 .   ? -24.02100 24.54800  -0.15000  1.000 16.49000 ? 106 HOH F O   1 
HETATM 7283 O O   . HOH L 4 .   ? -23.75000 27.18600  -0.16300  1.000 17.32000 ? 107 HOH F O   1 
HETATM 7284 O O   . HOH L 4 .   ? -24.10700 22.05100  4.77800   1.000 17.32000 ? 108 HOH F O   1 
HETATM 7285 O O   . HOH L 4 .   ? -29.77700 22.11000  0.00600   1.000 18.71000 ? 109 HOH F O   1 
HETATM 7286 O O   . HOH L 4 .   ? -15.48300 16.03800  -0.44200  1.000 16.71000 ? 110 HOH F O   1 
HETATM 7287 O O   . HOH L 4 .   ? -15.79600 22.89500  -1.91800  1.000 19.99000 ? 111 HOH F O   1 
HETATM 7288 O O   . HOH L 4 .   ? -27.35700 24.11000  -1.07400  1.000 21.43000 ? 112 HOH F O   1 
HETATM 7289 O O   . HOH L 4 .   ? -23.49000 23.10100  -2.65400  1.000 29.22000 ? 113 HOH F O   1 
HETATM 7290 O O   . HOH L 4 .   ? -27.49700 20.89800  -3.79500  1.000 29.31000 ? 114 HOH F O   1 
# 
