data_9L3Y
# 
_entry.id   9L3Y 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9L3Y         pdb_00009l3y 10.2210/pdb9l3y/pdb 
WWPDB D_1300054821 ?            ?                   
EMDB  EMD-62798    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-03-12 ? 
2 'EM metadata'     1 0 2025-03-12 ? 
3 Image             1 0 2025-03-12 ? 
4 'Primary map'     1 0 2025-03-12 ? 
5 'Structure model' 1 1 2025-06-11 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 Image             repository 'Initial release' ? ? 
4 4 'Primary map'     repository 'Initial release' ? ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 5 'Structure model' 'Data collection'     
2 5 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 5 'Structure model' citation 
2 5 'Structure model' em_admin 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 5 'Structure model' '_citation.journal_volume' 
2 5 'Structure model' '_citation.page_first'     
3 5 'Structure model' '_citation.page_last'      
4 5 'Structure model' '_em_admin.last_update'    
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9L3Y 
_pdbx_database_status.recvd_initial_deposition_date   2024-12-19 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    'GPCR Dock' 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
EMDB 'Raw consensus map of the G-protein coupled receptor 1 (GPR1) in complex with chemerin and Gi1' EMD-62794 
'consensus EM volume'  
EMDB 
'Focused refinement in chemerin and receptor regions of the G-protein coupled receptor 1 (GPR1) in complex with chemerin and Gi1' 
EMD-62795 'focused EM volume'    
EMDB 'Focused refinement in G protein region of the G-protein coupled receptor 1 (GPR1) in complex with chemerin and Gi1' 
EMD-62796 'focused EM volume'    
EMDB 'Cryo-EM structure of the G-protein coupled receptor 1 (GPR1) in complex with chemerin and Gi1' EMD-62798 
'associated EM volume' 
# 
_pdbx_contact_author.id                 5 
_pdbx_contact_author.email              zhuya@lglab.ac.cn 
_pdbx_contact_author.name_first         Ya 
_pdbx_contact_author.name_last          Zhu 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-1730-5279 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Zhu, Y.'  1 ? 
'He, M.'   2 ? 
'Wu, B.'   3 ? 
'Zhao, Q.' 4 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   CN 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Protein Cell' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           1674-8018 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            16 
_citation.language                  ? 
_citation.page_first                381 
_citation.page_last                 385 
_citation.title                     
'Structural insights into the distinct ligand recognition and signaling of the chemerin receptors CMKLR1 and GPR1.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1093/procel/pwae073 
_citation.pdbx_database_id_PubMed   39752296 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Lin, X.'   1  ? 
primary 'Zhao, L.'  2  ? 
primary 'Cai, H.'   3  ? 
primary 'Chang, X.' 4  ? 
primary 'Tang, Y.'  5  ? 
primary 'Luo, T.'   6  ? 
primary 'Wu, M.'    7  ? 
primary 'Yi, C.'    8  ? 
primary 'Ma, L.'    9  ? 
primary 'Chu, X.'   10 ? 
primary 'Han, S.'   11 ? 
primary 'Zhao, Q.'  12 ? 
primary 'Wu, B.'    13 ? 
primary 'He, M.'    14 ? 
primary 'Zhu, Y.'   15 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'Chemerin-like receptor 2'                                          42771.621 1 ? ?                            ? ? 
2 polymer man 'Retinoic acid receptor responder protein 2'                        15904.175 1 ? ?                            ? ? 
3 polymer man 'Guanine nucleotide-binding protein G(i) subunit alpha-1'           40447.141 1 ? S47C,G202T,G203A,E245A,A326S ? ? 
4 polymer man 'Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1'  37416.930 1 ? ?                            ? ? 
5 polymer man 'Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2' 7861.143  1 ? ?                            ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'G-protein coupled receptor 1 (GPR1),Chemerin chemokine-like receptor 2,Chemokine-like receptor 2' 
2 'Chemerin,RAR-responsive protein TIG2,Tazarotene-induced gene 2 protein'                           
3 'Adenylate cyclase-inhibiting G alpha protein'                                                     
4 'Transducin beta chain 1'                                                                          
5 'G gamma-I'                                                                                        
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MEDLEETLFEEFENYSYDLDYYSLESDLEEKVQLGVVHWVSLVLYCLAFVLGIPGNAIVIWFTGFKWKKTVTTLWFLNLA
IADFIFLLFLPLYISYVAMNFHWPFGIWLCKANSFTAQLNMFASVFFLTVISLDHYIHLIHPVLSHRHRTLKNSLIVIIF
IWLLASLIGGPALYFRDTVEFNNHTLCYNNFQKHDPDLTLIRHHVLTWVKFIIGYLFPLLTMSICYLCLIFKVKKRSILI
SSRHFWTILVVVVAFVVCWTPYHLFSIWELTIHHNSYSHHVMQAGIPLSTGLAFLNSCLNPILYVLISKKFQARFRSSVA
EIEFLEVLFQGPWSHPQFEKGGGSGGGSGGSAWSHPQFEKDYKDDDDK
;
;MEDLEETLFEEFENYSYDLDYYSLESDLEEKVQLGVVHWVSLVLYCLAFVLGIPGNAIVIWFTGFKWKKTVTTLWFLNLA
IADFIFLLFLPLYISYVAMNFHWPFGIWLCKANSFTAQLNMFASVFFLTVISLDHYIHLIHPVLSHRHRTLKNSLIVIIF
IWLLASLIGGPALYFRDTVEFNNHTLCYNNFQKHDPDLTLIRHHVLTWVKFIIGYLFPLLTMSICYLCLIFKVKKRSILI
SSRHFWTILVVVVAFVVCWTPYHLFSIWELTIHHNSYSHHVMQAGIPLSTGLAFLNSCLNPILYVLISKKFQARFRSSVA
EIEFLEVLFQGPWSHPQFEKGGGSGGGSGGSAWSHPQFEKDYKDDDDK
;
R ? 
2 'polypeptide(L)' no no 
;ELTEAQRRGLQVALEEFHKHPPVQWAFQETSVESAVDTPFPAGIFVRLEFKLQQTSCRKRDWKKPECKVRPNGRKRKCLA
CIKLGSEDKVLGRLVHCPIETQVLREAEEHQETQCLRVQRAGEDPHSFYFPGQFAFS
;
;ELTEAQRRGLQVALEEFHKHPPVQWAFQETSVESAVDTPFPAGIFVRLEFKLQQTSCRKRDWKKPECKVRPNGRKRKCLA
CIKLGSEDKVLGRLVHCPIETQVLREAEEHQETQCLRVQRAGEDPHSFYFPGQFAFS
;
L ? 
3 'polypeptide(L)' no no 
;MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKCTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQS
IIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLD
RIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVTAQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM
NRMHASMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIY
THFTCSTDTKNVQFVFDAVTDVIIKNNLKDCGLF
;
;MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKCTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQS
IIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLD
RIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVTAQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM
NRMHASMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIY
THFTCSTDTKNVQFVFDAVTDVIIKNNLKDCGLF
;
A ? 
4 'polypeptide(L)' no no 
;MSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLI
IWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTS
SGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNA
FATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGV
TDDGMAVATGSWDSFLKIWN
;
;MSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLI
IWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTS
SGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNA
FATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGV
TDDGMAVATGSWDSFLKIWN
;
B ? 
5 'polypeptide(L)' no no MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL 
MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL C ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLU n 
1 3   ASP n 
1 4   LEU n 
1 5   GLU n 
1 6   GLU n 
1 7   THR n 
1 8   LEU n 
1 9   PHE n 
1 10  GLU n 
1 11  GLU n 
1 12  PHE n 
1 13  GLU n 
1 14  ASN n 
1 15  TYR n 
1 16  SER n 
1 17  TYR n 
1 18  ASP n 
1 19  LEU n 
1 20  ASP n 
1 21  TYR n 
1 22  TYR n 
1 23  SER n 
1 24  LEU n 
1 25  GLU n 
1 26  SER n 
1 27  ASP n 
1 28  LEU n 
1 29  GLU n 
1 30  GLU n 
1 31  LYS n 
1 32  VAL n 
1 33  GLN n 
1 34  LEU n 
1 35  GLY n 
1 36  VAL n 
1 37  VAL n 
1 38  HIS n 
1 39  TRP n 
1 40  VAL n 
1 41  SER n 
1 42  LEU n 
1 43  VAL n 
1 44  LEU n 
1 45  TYR n 
1 46  CYS n 
1 47  LEU n 
1 48  ALA n 
1 49  PHE n 
1 50  VAL n 
1 51  LEU n 
1 52  GLY n 
1 53  ILE n 
1 54  PRO n 
1 55  GLY n 
1 56  ASN n 
1 57  ALA n 
1 58  ILE n 
1 59  VAL n 
1 60  ILE n 
1 61  TRP n 
1 62  PHE n 
1 63  THR n 
1 64  GLY n 
1 65  PHE n 
1 66  LYS n 
1 67  TRP n 
1 68  LYS n 
1 69  LYS n 
1 70  THR n 
1 71  VAL n 
1 72  THR n 
1 73  THR n 
1 74  LEU n 
1 75  TRP n 
1 76  PHE n 
1 77  LEU n 
1 78  ASN n 
1 79  LEU n 
1 80  ALA n 
1 81  ILE n 
1 82  ALA n 
1 83  ASP n 
1 84  PHE n 
1 85  ILE n 
1 86  PHE n 
1 87  LEU n 
1 88  LEU n 
1 89  PHE n 
1 90  LEU n 
1 91  PRO n 
1 92  LEU n 
1 93  TYR n 
1 94  ILE n 
1 95  SER n 
1 96  TYR n 
1 97  VAL n 
1 98  ALA n 
1 99  MET n 
1 100 ASN n 
1 101 PHE n 
1 102 HIS n 
1 103 TRP n 
1 104 PRO n 
1 105 PHE n 
1 106 GLY n 
1 107 ILE n 
1 108 TRP n 
1 109 LEU n 
1 110 CYS n 
1 111 LYS n 
1 112 ALA n 
1 113 ASN n 
1 114 SER n 
1 115 PHE n 
1 116 THR n 
1 117 ALA n 
1 118 GLN n 
1 119 LEU n 
1 120 ASN n 
1 121 MET n 
1 122 PHE n 
1 123 ALA n 
1 124 SER n 
1 125 VAL n 
1 126 PHE n 
1 127 PHE n 
1 128 LEU n 
1 129 THR n 
1 130 VAL n 
1 131 ILE n 
1 132 SER n 
1 133 LEU n 
1 134 ASP n 
1 135 HIS n 
1 136 TYR n 
1 137 ILE n 
1 138 HIS n 
1 139 LEU n 
1 140 ILE n 
1 141 HIS n 
1 142 PRO n 
1 143 VAL n 
1 144 LEU n 
1 145 SER n 
1 146 HIS n 
1 147 ARG n 
1 148 HIS n 
1 149 ARG n 
1 150 THR n 
1 151 LEU n 
1 152 LYS n 
1 153 ASN n 
1 154 SER n 
1 155 LEU n 
1 156 ILE n 
1 157 VAL n 
1 158 ILE n 
1 159 ILE n 
1 160 PHE n 
1 161 ILE n 
1 162 TRP n 
1 163 LEU n 
1 164 LEU n 
1 165 ALA n 
1 166 SER n 
1 167 LEU n 
1 168 ILE n 
1 169 GLY n 
1 170 GLY n 
1 171 PRO n 
1 172 ALA n 
1 173 LEU n 
1 174 TYR n 
1 175 PHE n 
1 176 ARG n 
1 177 ASP n 
1 178 THR n 
1 179 VAL n 
1 180 GLU n 
1 181 PHE n 
1 182 ASN n 
1 183 ASN n 
1 184 HIS n 
1 185 THR n 
1 186 LEU n 
1 187 CYS n 
1 188 TYR n 
1 189 ASN n 
1 190 ASN n 
1 191 PHE n 
1 192 GLN n 
1 193 LYS n 
1 194 HIS n 
1 195 ASP n 
1 196 PRO n 
1 197 ASP n 
1 198 LEU n 
1 199 THR n 
1 200 LEU n 
1 201 ILE n 
1 202 ARG n 
1 203 HIS n 
1 204 HIS n 
1 205 VAL n 
1 206 LEU n 
1 207 THR n 
1 208 TRP n 
1 209 VAL n 
1 210 LYS n 
1 211 PHE n 
1 212 ILE n 
1 213 ILE n 
1 214 GLY n 
1 215 TYR n 
1 216 LEU n 
1 217 PHE n 
1 218 PRO n 
1 219 LEU n 
1 220 LEU n 
1 221 THR n 
1 222 MET n 
1 223 SER n 
1 224 ILE n 
1 225 CYS n 
1 226 TYR n 
1 227 LEU n 
1 228 CYS n 
1 229 LEU n 
1 230 ILE n 
1 231 PHE n 
1 232 LYS n 
1 233 VAL n 
1 234 LYS n 
1 235 LYS n 
1 236 ARG n 
1 237 SER n 
1 238 ILE n 
1 239 LEU n 
1 240 ILE n 
1 241 SER n 
1 242 SER n 
1 243 ARG n 
1 244 HIS n 
1 245 PHE n 
1 246 TRP n 
1 247 THR n 
1 248 ILE n 
1 249 LEU n 
1 250 VAL n 
1 251 VAL n 
1 252 VAL n 
1 253 VAL n 
1 254 ALA n 
1 255 PHE n 
1 256 VAL n 
1 257 VAL n 
1 258 CYS n 
1 259 TRP n 
1 260 THR n 
1 261 PRO n 
1 262 TYR n 
1 263 HIS n 
1 264 LEU n 
1 265 PHE n 
1 266 SER n 
1 267 ILE n 
1 268 TRP n 
1 269 GLU n 
1 270 LEU n 
1 271 THR n 
1 272 ILE n 
1 273 HIS n 
1 274 HIS n 
1 275 ASN n 
1 276 SER n 
1 277 TYR n 
1 278 SER n 
1 279 HIS n 
1 280 HIS n 
1 281 VAL n 
1 282 MET n 
1 283 GLN n 
1 284 ALA n 
1 285 GLY n 
1 286 ILE n 
1 287 PRO n 
1 288 LEU n 
1 289 SER n 
1 290 THR n 
1 291 GLY n 
1 292 LEU n 
1 293 ALA n 
1 294 PHE n 
1 295 LEU n 
1 296 ASN n 
1 297 SER n 
1 298 CYS n 
1 299 LEU n 
1 300 ASN n 
1 301 PRO n 
1 302 ILE n 
1 303 LEU n 
1 304 TYR n 
1 305 VAL n 
1 306 LEU n 
1 307 ILE n 
1 308 SER n 
1 309 LYS n 
1 310 LYS n 
1 311 PHE n 
1 312 GLN n 
1 313 ALA n 
1 314 ARG n 
1 315 PHE n 
1 316 ARG n 
1 317 SER n 
1 318 SER n 
1 319 VAL n 
1 320 ALA n 
1 321 GLU n 
1 322 ILE n 
1 323 GLU n 
1 324 PHE n 
1 325 LEU n 
1 326 GLU n 
1 327 VAL n 
1 328 LEU n 
1 329 PHE n 
1 330 GLN n 
1 331 GLY n 
1 332 PRO n 
1 333 TRP n 
1 334 SER n 
1 335 HIS n 
1 336 PRO n 
1 337 GLN n 
1 338 PHE n 
1 339 GLU n 
1 340 LYS n 
1 341 GLY n 
1 342 GLY n 
1 343 GLY n 
1 344 SER n 
1 345 GLY n 
1 346 GLY n 
1 347 GLY n 
1 348 SER n 
1 349 GLY n 
1 350 GLY n 
1 351 SER n 
1 352 ALA n 
1 353 TRP n 
1 354 SER n 
1 355 HIS n 
1 356 PRO n 
1 357 GLN n 
1 358 PHE n 
1 359 GLU n 
1 360 LYS n 
1 361 ASP n 
1 362 TYR n 
1 363 LYS n 
1 364 ASP n 
1 365 ASP n 
1 366 ASP n 
1 367 ASP n 
1 368 LYS n 
2 1   GLU n 
2 2   LEU n 
2 3   THR n 
2 4   GLU n 
2 5   ALA n 
2 6   GLN n 
2 7   ARG n 
2 8   ARG n 
2 9   GLY n 
2 10  LEU n 
2 11  GLN n 
2 12  VAL n 
2 13  ALA n 
2 14  LEU n 
2 15  GLU n 
2 16  GLU n 
2 17  PHE n 
2 18  HIS n 
2 19  LYS n 
2 20  HIS n 
2 21  PRO n 
2 22  PRO n 
2 23  VAL n 
2 24  GLN n 
2 25  TRP n 
2 26  ALA n 
2 27  PHE n 
2 28  GLN n 
2 29  GLU n 
2 30  THR n 
2 31  SER n 
2 32  VAL n 
2 33  GLU n 
2 34  SER n 
2 35  ALA n 
2 36  VAL n 
2 37  ASP n 
2 38  THR n 
2 39  PRO n 
2 40  PHE n 
2 41  PRO n 
2 42  ALA n 
2 43  GLY n 
2 44  ILE n 
2 45  PHE n 
2 46  VAL n 
2 47  ARG n 
2 48  LEU n 
2 49  GLU n 
2 50  PHE n 
2 51  LYS n 
2 52  LEU n 
2 53  GLN n 
2 54  GLN n 
2 55  THR n 
2 56  SER n 
2 57  CYS n 
2 58  ARG n 
2 59  LYS n 
2 60  ARG n 
2 61  ASP n 
2 62  TRP n 
2 63  LYS n 
2 64  LYS n 
2 65  PRO n 
2 66  GLU n 
2 67  CYS n 
2 68  LYS n 
2 69  VAL n 
2 70  ARG n 
2 71  PRO n 
2 72  ASN n 
2 73  GLY n 
2 74  ARG n 
2 75  LYS n 
2 76  ARG n 
2 77  LYS n 
2 78  CYS n 
2 79  LEU n 
2 80  ALA n 
2 81  CYS n 
2 82  ILE n 
2 83  LYS n 
2 84  LEU n 
2 85  GLY n 
2 86  SER n 
2 87  GLU n 
2 88  ASP n 
2 89  LYS n 
2 90  VAL n 
2 91  LEU n 
2 92  GLY n 
2 93  ARG n 
2 94  LEU n 
2 95  VAL n 
2 96  HIS n 
2 97  CYS n 
2 98  PRO n 
2 99  ILE n 
2 100 GLU n 
2 101 THR n 
2 102 GLN n 
2 103 VAL n 
2 104 LEU n 
2 105 ARG n 
2 106 GLU n 
2 107 ALA n 
2 108 GLU n 
2 109 GLU n 
2 110 HIS n 
2 111 GLN n 
2 112 GLU n 
2 113 THR n 
2 114 GLN n 
2 115 CYS n 
2 116 LEU n 
2 117 ARG n 
2 118 VAL n 
2 119 GLN n 
2 120 ARG n 
2 121 ALA n 
2 122 GLY n 
2 123 GLU n 
2 124 ASP n 
2 125 PRO n 
2 126 HIS n 
2 127 SER n 
2 128 PHE n 
2 129 TYR n 
2 130 PHE n 
2 131 PRO n 
2 132 GLY n 
2 133 GLN n 
2 134 PHE n 
2 135 ALA n 
2 136 PHE n 
2 137 SER n 
3 1   MET n 
3 2   GLY n 
3 3   CYS n 
3 4   THR n 
3 5   LEU n 
3 6   SER n 
3 7   ALA n 
3 8   GLU n 
3 9   ASP n 
3 10  LYS n 
3 11  ALA n 
3 12  ALA n 
3 13  VAL n 
3 14  GLU n 
3 15  ARG n 
3 16  SER n 
3 17  LYS n 
3 18  MET n 
3 19  ILE n 
3 20  ASP n 
3 21  ARG n 
3 22  ASN n 
3 23  LEU n 
3 24  ARG n 
3 25  GLU n 
3 26  ASP n 
3 27  GLY n 
3 28  GLU n 
3 29  LYS n 
3 30  ALA n 
3 31  ALA n 
3 32  ARG n 
3 33  GLU n 
3 34  VAL n 
3 35  LYS n 
3 36  LEU n 
3 37  LEU n 
3 38  LEU n 
3 39  LEU n 
3 40  GLY n 
3 41  ALA n 
3 42  GLY n 
3 43  GLU n 
3 44  SER n 
3 45  GLY n 
3 46  LYS n 
3 47  CYS n 
3 48  THR n 
3 49  ILE n 
3 50  VAL n 
3 51  LYS n 
3 52  GLN n 
3 53  MET n 
3 54  LYS n 
3 55  ILE n 
3 56  ILE n 
3 57  HIS n 
3 58  GLU n 
3 59  ALA n 
3 60  GLY n 
3 61  TYR n 
3 62  SER n 
3 63  GLU n 
3 64  GLU n 
3 65  GLU n 
3 66  CYS n 
3 67  LYS n 
3 68  GLN n 
3 69  TYR n 
3 70  LYS n 
3 71  ALA n 
3 72  VAL n 
3 73  VAL n 
3 74  TYR n 
3 75  SER n 
3 76  ASN n 
3 77  THR n 
3 78  ILE n 
3 79  GLN n 
3 80  SER n 
3 81  ILE n 
3 82  ILE n 
3 83  ALA n 
3 84  ILE n 
3 85  ILE n 
3 86  ARG n 
3 87  ALA n 
3 88  MET n 
3 89  GLY n 
3 90  ARG n 
3 91  LEU n 
3 92  LYS n 
3 93  ILE n 
3 94  ASP n 
3 95  PHE n 
3 96  GLY n 
3 97  ASP n 
3 98  SER n 
3 99  ALA n 
3 100 ARG n 
3 101 ALA n 
3 102 ASP n 
3 103 ASP n 
3 104 ALA n 
3 105 ARG n 
3 106 GLN n 
3 107 LEU n 
3 108 PHE n 
3 109 VAL n 
3 110 LEU n 
3 111 ALA n 
3 112 GLY n 
3 113 ALA n 
3 114 ALA n 
3 115 GLU n 
3 116 GLU n 
3 117 GLY n 
3 118 PHE n 
3 119 MET n 
3 120 THR n 
3 121 ALA n 
3 122 GLU n 
3 123 LEU n 
3 124 ALA n 
3 125 GLY n 
3 126 VAL n 
3 127 ILE n 
3 128 LYS n 
3 129 ARG n 
3 130 LEU n 
3 131 TRP n 
3 132 LYS n 
3 133 ASP n 
3 134 SER n 
3 135 GLY n 
3 136 VAL n 
3 137 GLN n 
3 138 ALA n 
3 139 CYS n 
3 140 PHE n 
3 141 ASN n 
3 142 ARG n 
3 143 SER n 
3 144 ARG n 
3 145 GLU n 
3 146 TYR n 
3 147 GLN n 
3 148 LEU n 
3 149 ASN n 
3 150 ASP n 
3 151 SER n 
3 152 ALA n 
3 153 ALA n 
3 154 TYR n 
3 155 TYR n 
3 156 LEU n 
3 157 ASN n 
3 158 ASP n 
3 159 LEU n 
3 160 ASP n 
3 161 ARG n 
3 162 ILE n 
3 163 ALA n 
3 164 GLN n 
3 165 PRO n 
3 166 ASN n 
3 167 TYR n 
3 168 ILE n 
3 169 PRO n 
3 170 THR n 
3 171 GLN n 
3 172 GLN n 
3 173 ASP n 
3 174 VAL n 
3 175 LEU n 
3 176 ARG n 
3 177 THR n 
3 178 ARG n 
3 179 VAL n 
3 180 LYS n 
3 181 THR n 
3 182 THR n 
3 183 GLY n 
3 184 ILE n 
3 185 VAL n 
3 186 GLU n 
3 187 THR n 
3 188 HIS n 
3 189 PHE n 
3 190 THR n 
3 191 PHE n 
3 192 LYS n 
3 193 ASP n 
3 194 LEU n 
3 195 HIS n 
3 196 PHE n 
3 197 LYS n 
3 198 MET n 
3 199 PHE n 
3 200 ASP n 
3 201 VAL n 
3 202 THR n 
3 203 ALA n 
3 204 GLN n 
3 205 ARG n 
3 206 SER n 
3 207 GLU n 
3 208 ARG n 
3 209 LYS n 
3 210 LYS n 
3 211 TRP n 
3 212 ILE n 
3 213 HIS n 
3 214 CYS n 
3 215 PHE n 
3 216 GLU n 
3 217 GLY n 
3 218 VAL n 
3 219 THR n 
3 220 ALA n 
3 221 ILE n 
3 222 ILE n 
3 223 PHE n 
3 224 CYS n 
3 225 VAL n 
3 226 ALA n 
3 227 LEU n 
3 228 SER n 
3 229 ASP n 
3 230 TYR n 
3 231 ASP n 
3 232 LEU n 
3 233 VAL n 
3 234 LEU n 
3 235 ALA n 
3 236 GLU n 
3 237 ASP n 
3 238 GLU n 
3 239 GLU n 
3 240 MET n 
3 241 ASN n 
3 242 ARG n 
3 243 MET n 
3 244 HIS n 
3 245 ALA n 
3 246 SER n 
3 247 MET n 
3 248 LYS n 
3 249 LEU n 
3 250 PHE n 
3 251 ASP n 
3 252 SER n 
3 253 ILE n 
3 254 CYS n 
3 255 ASN n 
3 256 ASN n 
3 257 LYS n 
3 258 TRP n 
3 259 PHE n 
3 260 THR n 
3 261 ASP n 
3 262 THR n 
3 263 SER n 
3 264 ILE n 
3 265 ILE n 
3 266 LEU n 
3 267 PHE n 
3 268 LEU n 
3 269 ASN n 
3 270 LYS n 
3 271 LYS n 
3 272 ASP n 
3 273 LEU n 
3 274 PHE n 
3 275 GLU n 
3 276 GLU n 
3 277 LYS n 
3 278 ILE n 
3 279 LYS n 
3 280 LYS n 
3 281 SER n 
3 282 PRO n 
3 283 LEU n 
3 284 THR n 
3 285 ILE n 
3 286 CYS n 
3 287 TYR n 
3 288 PRO n 
3 289 GLU n 
3 290 TYR n 
3 291 ALA n 
3 292 GLY n 
3 293 SER n 
3 294 ASN n 
3 295 THR n 
3 296 TYR n 
3 297 GLU n 
3 298 GLU n 
3 299 ALA n 
3 300 ALA n 
3 301 ALA n 
3 302 TYR n 
3 303 ILE n 
3 304 GLN n 
3 305 CYS n 
3 306 GLN n 
3 307 PHE n 
3 308 GLU n 
3 309 ASP n 
3 310 LEU n 
3 311 ASN n 
3 312 LYS n 
3 313 ARG n 
3 314 LYS n 
3 315 ASP n 
3 316 THR n 
3 317 LYS n 
3 318 GLU n 
3 319 ILE n 
3 320 TYR n 
3 321 THR n 
3 322 HIS n 
3 323 PHE n 
3 324 THR n 
3 325 CYS n 
3 326 SER n 
3 327 THR n 
3 328 ASP n 
3 329 THR n 
3 330 LYS n 
3 331 ASN n 
3 332 VAL n 
3 333 GLN n 
3 334 PHE n 
3 335 VAL n 
3 336 PHE n 
3 337 ASP n 
3 338 ALA n 
3 339 VAL n 
3 340 THR n 
3 341 ASP n 
3 342 VAL n 
3 343 ILE n 
3 344 ILE n 
3 345 LYS n 
3 346 ASN n 
3 347 ASN n 
3 348 LEU n 
3 349 LYS n 
3 350 ASP n 
3 351 CYS n 
3 352 GLY n 
3 353 LEU n 
3 354 PHE n 
4 1   MET n 
4 2   SER n 
4 3   GLU n 
4 4   LEU n 
4 5   ASP n 
4 6   GLN n 
4 7   LEU n 
4 8   ARG n 
4 9   GLN n 
4 10  GLU n 
4 11  ALA n 
4 12  GLU n 
4 13  GLN n 
4 14  LEU n 
4 15  LYS n 
4 16  ASN n 
4 17  GLN n 
4 18  ILE n 
4 19  ARG n 
4 20  ASP n 
4 21  ALA n 
4 22  ARG n 
4 23  LYS n 
4 24  ALA n 
4 25  CYS n 
4 26  ALA n 
4 27  ASP n 
4 28  ALA n 
4 29  THR n 
4 30  LEU n 
4 31  SER n 
4 32  GLN n 
4 33  ILE n 
4 34  THR n 
4 35  ASN n 
4 36  ASN n 
4 37  ILE n 
4 38  ASP n 
4 39  PRO n 
4 40  VAL n 
4 41  GLY n 
4 42  ARG n 
4 43  ILE n 
4 44  GLN n 
4 45  MET n 
4 46  ARG n 
4 47  THR n 
4 48  ARG n 
4 49  ARG n 
4 50  THR n 
4 51  LEU n 
4 52  ARG n 
4 53  GLY n 
4 54  HIS n 
4 55  LEU n 
4 56  ALA n 
4 57  LYS n 
4 58  ILE n 
4 59  TYR n 
4 60  ALA n 
4 61  MET n 
4 62  HIS n 
4 63  TRP n 
4 64  GLY n 
4 65  THR n 
4 66  ASP n 
4 67  SER n 
4 68  ARG n 
4 69  LEU n 
4 70  LEU n 
4 71  VAL n 
4 72  SER n 
4 73  ALA n 
4 74  SER n 
4 75  GLN n 
4 76  ASP n 
4 77  GLY n 
4 78  LYS n 
4 79  LEU n 
4 80  ILE n 
4 81  ILE n 
4 82  TRP n 
4 83  ASP n 
4 84  SER n 
4 85  TYR n 
4 86  THR n 
4 87  THR n 
4 88  ASN n 
4 89  LYS n 
4 90  VAL n 
4 91  HIS n 
4 92  ALA n 
4 93  ILE n 
4 94  PRO n 
4 95  LEU n 
4 96  ARG n 
4 97  SER n 
4 98  SER n 
4 99  TRP n 
4 100 VAL n 
4 101 MET n 
4 102 THR n 
4 103 CYS n 
4 104 ALA n 
4 105 TYR n 
4 106 ALA n 
4 107 PRO n 
4 108 SER n 
4 109 GLY n 
4 110 ASN n 
4 111 TYR n 
4 112 VAL n 
4 113 ALA n 
4 114 CYS n 
4 115 GLY n 
4 116 GLY n 
4 117 LEU n 
4 118 ASP n 
4 119 ASN n 
4 120 ILE n 
4 121 CYS n 
4 122 SER n 
4 123 ILE n 
4 124 TYR n 
4 125 ASN n 
4 126 LEU n 
4 127 LYS n 
4 128 THR n 
4 129 ARG n 
4 130 GLU n 
4 131 GLY n 
4 132 ASN n 
4 133 VAL n 
4 134 ARG n 
4 135 VAL n 
4 136 SER n 
4 137 ARG n 
4 138 GLU n 
4 139 LEU n 
4 140 ALA n 
4 141 GLY n 
4 142 HIS n 
4 143 THR n 
4 144 GLY n 
4 145 TYR n 
4 146 LEU n 
4 147 SER n 
4 148 CYS n 
4 149 CYS n 
4 150 ARG n 
4 151 PHE n 
4 152 LEU n 
4 153 ASP n 
4 154 ASP n 
4 155 ASN n 
4 156 GLN n 
4 157 ILE n 
4 158 VAL n 
4 159 THR n 
4 160 SER n 
4 161 SER n 
4 162 GLY n 
4 163 ASP n 
4 164 THR n 
4 165 THR n 
4 166 CYS n 
4 167 ALA n 
4 168 LEU n 
4 169 TRP n 
4 170 ASP n 
4 171 ILE n 
4 172 GLU n 
4 173 THR n 
4 174 GLY n 
4 175 GLN n 
4 176 GLN n 
4 177 THR n 
4 178 THR n 
4 179 THR n 
4 180 PHE n 
4 181 THR n 
4 182 GLY n 
4 183 HIS n 
4 184 THR n 
4 185 GLY n 
4 186 ASP n 
4 187 VAL n 
4 188 MET n 
4 189 SER n 
4 190 LEU n 
4 191 SER n 
4 192 LEU n 
4 193 ALA n 
4 194 PRO n 
4 195 ASP n 
4 196 THR n 
4 197 ARG n 
4 198 LEU n 
4 199 PHE n 
4 200 VAL n 
4 201 SER n 
4 202 GLY n 
4 203 ALA n 
4 204 CYS n 
4 205 ASP n 
4 206 ALA n 
4 207 SER n 
4 208 ALA n 
4 209 LYS n 
4 210 LEU n 
4 211 TRP n 
4 212 ASP n 
4 213 VAL n 
4 214 ARG n 
4 215 GLU n 
4 216 GLY n 
4 217 MET n 
4 218 CYS n 
4 219 ARG n 
4 220 GLN n 
4 221 THR n 
4 222 PHE n 
4 223 THR n 
4 224 GLY n 
4 225 HIS n 
4 226 GLU n 
4 227 SER n 
4 228 ASP n 
4 229 ILE n 
4 230 ASN n 
4 231 ALA n 
4 232 ILE n 
4 233 CYS n 
4 234 PHE n 
4 235 PHE n 
4 236 PRO n 
4 237 ASN n 
4 238 GLY n 
4 239 ASN n 
4 240 ALA n 
4 241 PHE n 
4 242 ALA n 
4 243 THR n 
4 244 GLY n 
4 245 SER n 
4 246 ASP n 
4 247 ASP n 
4 248 ALA n 
4 249 THR n 
4 250 CYS n 
4 251 ARG n 
4 252 LEU n 
4 253 PHE n 
4 254 ASP n 
4 255 LEU n 
4 256 ARG n 
4 257 ALA n 
4 258 ASP n 
4 259 GLN n 
4 260 GLU n 
4 261 LEU n 
4 262 MET n 
4 263 THR n 
4 264 TYR n 
4 265 SER n 
4 266 HIS n 
4 267 ASP n 
4 268 ASN n 
4 269 ILE n 
4 270 ILE n 
4 271 CYS n 
4 272 GLY n 
4 273 ILE n 
4 274 THR n 
4 275 SER n 
4 276 VAL n 
4 277 SER n 
4 278 PHE n 
4 279 SER n 
4 280 LYS n 
4 281 SER n 
4 282 GLY n 
4 283 ARG n 
4 284 LEU n 
4 285 LEU n 
4 286 LEU n 
4 287 ALA n 
4 288 GLY n 
4 289 TYR n 
4 290 ASP n 
4 291 ASP n 
4 292 PHE n 
4 293 ASN n 
4 294 CYS n 
4 295 ASN n 
4 296 VAL n 
4 297 TRP n 
4 298 ASP n 
4 299 ALA n 
4 300 LEU n 
4 301 LYS n 
4 302 ALA n 
4 303 ASP n 
4 304 ARG n 
4 305 ALA n 
4 306 GLY n 
4 307 VAL n 
4 308 LEU n 
4 309 ALA n 
4 310 GLY n 
4 311 HIS n 
4 312 ASP n 
4 313 ASN n 
4 314 ARG n 
4 315 VAL n 
4 316 SER n 
4 317 CYS n 
4 318 LEU n 
4 319 GLY n 
4 320 VAL n 
4 321 THR n 
4 322 ASP n 
4 323 ASP n 
4 324 GLY n 
4 325 MET n 
4 326 ALA n 
4 327 VAL n 
4 328 ALA n 
4 329 THR n 
4 330 GLY n 
4 331 SER n 
4 332 TRP n 
4 333 ASP n 
4 334 SER n 
4 335 PHE n 
4 336 LEU n 
4 337 LYS n 
4 338 ILE n 
4 339 TRP n 
4 340 ASN n 
5 1   MET n 
5 2   ALA n 
5 3   SER n 
5 4   ASN n 
5 5   ASN n 
5 6   THR n 
5 7   ALA n 
5 8   SER n 
5 9   ILE n 
5 10  ALA n 
5 11  GLN n 
5 12  ALA n 
5 13  ARG n 
5 14  LYS n 
5 15  LEU n 
5 16  VAL n 
5 17  GLU n 
5 18  GLN n 
5 19  LEU n 
5 20  LYS n 
5 21  MET n 
5 22  GLU n 
5 23  ALA n 
5 24  ASN n 
5 25  ILE n 
5 26  ASP n 
5 27  ARG n 
5 28  ILE n 
5 29  LYS n 
5 30  VAL n 
5 31  SER n 
5 32  LYS n 
5 33  ALA n 
5 34  ALA n 
5 35  ALA n 
5 36  ASP n 
5 37  LEU n 
5 38  MET n 
5 39  ALA n 
5 40  TYR n 
5 41  CYS n 
5 42  GLU n 
5 43  ALA n 
5 44  HIS n 
5 45  ALA n 
5 46  LYS n 
5 47  GLU n 
5 48  ASP n 
5 49  PRO n 
5 50  LEU n 
5 51  LEU n 
5 52  THR n 
5 53  PRO n 
5 54  VAL n 
5 55  PRO n 
5 56  ALA n 
5 57  SER n 
5 58  GLU n 
5 59  ASN n 
5 60  PRO n 
5 61  PHE n 
5 62  ARG n 
5 63  GLU n 
5 64  LYS n 
5 65  LYS n 
5 66  PHE n 
5 67  PHE n 
5 68  CYS n 
5 69  ALA n 
5 70  ILE n 
5 71  LEU n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 368 human ? 'CMKLR2, GPR1'  ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 137 human ? 'RARRES2, TIG2' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 354 human ? GNAI1           ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 'Biological sequence' 1 340 human ? GNB1            ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
5 1 sample 'Biological sequence' 1 71  human ? GNG2            ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   R . n 
A 1 2   GLU 2   2   ?   ?   ?   R . n 
A 1 3   ASP 3   3   ?   ?   ?   R . n 
A 1 4   LEU 4   4   ?   ?   ?   R . n 
A 1 5   GLU 5   5   ?   ?   ?   R . n 
A 1 6   GLU 6   6   ?   ?   ?   R . n 
A 1 7   THR 7   7   ?   ?   ?   R . n 
A 1 8   LEU 8   8   ?   ?   ?   R . n 
A 1 9   PHE 9   9   ?   ?   ?   R . n 
A 1 10  GLU 10  10  ?   ?   ?   R . n 
A 1 11  GLU 11  11  ?   ?   ?   R . n 
A 1 12  PHE 12  12  12  PHE PHE R . n 
A 1 13  GLU 13  13  13  GLU GLU R . n 
A 1 14  ASN 14  14  14  ASN ASN R . n 
A 1 15  TYR 15  15  15  TYR TYR R . n 
A 1 16  SER 16  16  16  SER SER R . n 
A 1 17  TYR 17  17  17  TYR TYR R . n 
A 1 18  ASP 18  18  18  ASP ASP R . n 
A 1 19  LEU 19  19  19  LEU LEU R . n 
A 1 20  ASP 20  20  20  ASP ASP R . n 
A 1 21  TYR 21  21  21  TYR TYR R . n 
A 1 22  TYR 22  22  22  TYR TYR R . n 
A 1 23  SER 23  23  23  SER SER R . n 
A 1 24  LEU 24  24  24  LEU LEU R . n 
A 1 25  GLU 25  25  25  GLU GLU R . n 
A 1 26  SER 26  26  26  SER SER R . n 
A 1 27  ASP 27  27  27  ASP ASP R . n 
A 1 28  LEU 28  28  28  LEU LEU R . n 
A 1 29  GLU 29  29  ?   ?   ?   R . n 
A 1 30  GLU 30  30  ?   ?   ?   R . n 
A 1 31  LYS 31  31  ?   ?   ?   R . n 
A 1 32  VAL 32  32  ?   ?   ?   R . n 
A 1 33  GLN 33  33  ?   ?   ?   R . n 
A 1 34  LEU 34  34  ?   ?   ?   R . n 
A 1 35  GLY 35  35  35  GLY GLY R . n 
A 1 36  VAL 36  36  36  VAL VAL R . n 
A 1 37  VAL 37  37  37  VAL VAL R . n 
A 1 38  HIS 38  38  38  HIS HIS R . n 
A 1 39  TRP 39  39  39  TRP TRP R . n 
A 1 40  VAL 40  40  40  VAL VAL R . n 
A 1 41  SER 41  41  41  SER SER R . n 
A 1 42  LEU 42  42  42  LEU LEU R . n 
A 1 43  VAL 43  43  43  VAL VAL R . n 
A 1 44  LEU 44  44  44  LEU LEU R . n 
A 1 45  TYR 45  45  45  TYR TYR R . n 
A 1 46  CYS 46  46  46  CYS CYS R . n 
A 1 47  LEU 47  47  47  LEU LEU R . n 
A 1 48  ALA 48  48  48  ALA ALA R . n 
A 1 49  PHE 49  49  49  PHE PHE R . n 
A 1 50  VAL 50  50  50  VAL VAL R . n 
A 1 51  LEU 51  51  51  LEU LEU R . n 
A 1 52  GLY 52  52  52  GLY GLY R . n 
A 1 53  ILE 53  53  53  ILE ILE R . n 
A 1 54  PRO 54  54  54  PRO PRO R . n 
A 1 55  GLY 55  55  55  GLY GLY R . n 
A 1 56  ASN 56  56  56  ASN ASN R . n 
A 1 57  ALA 57  57  57  ALA ALA R . n 
A 1 58  ILE 58  58  58  ILE ILE R . n 
A 1 59  VAL 59  59  59  VAL VAL R . n 
A 1 60  ILE 60  60  60  ILE ILE R . n 
A 1 61  TRP 61  61  61  TRP TRP R . n 
A 1 62  PHE 62  62  62  PHE PHE R . n 
A 1 63  THR 63  63  63  THR THR R . n 
A 1 64  GLY 64  64  64  GLY GLY R . n 
A 1 65  PHE 65  65  65  PHE PHE R . n 
A 1 66  LYS 66  66  66  LYS LYS R . n 
A 1 67  TRP 67  67  67  TRP TRP R . n 
A 1 68  LYS 68  68  68  LYS LYS R . n 
A 1 69  LYS 69  69  69  LYS LYS R . n 
A 1 70  THR 70  70  70  THR THR R . n 
A 1 71  VAL 71  71  71  VAL VAL R . n 
A 1 72  THR 72  72  72  THR THR R . n 
A 1 73  THR 73  73  73  THR THR R . n 
A 1 74  LEU 74  74  74  LEU LEU R . n 
A 1 75  TRP 75  75  75  TRP TRP R . n 
A 1 76  PHE 76  76  76  PHE PHE R . n 
A 1 77  LEU 77  77  77  LEU LEU R . n 
A 1 78  ASN 78  78  78  ASN ASN R . n 
A 1 79  LEU 79  79  79  LEU LEU R . n 
A 1 80  ALA 80  80  80  ALA ALA R . n 
A 1 81  ILE 81  81  81  ILE ILE R . n 
A 1 82  ALA 82  82  82  ALA ALA R . n 
A 1 83  ASP 83  83  83  ASP ASP R . n 
A 1 84  PHE 84  84  84  PHE PHE R . n 
A 1 85  ILE 85  85  85  ILE ILE R . n 
A 1 86  PHE 86  86  86  PHE PHE R . n 
A 1 87  LEU 87  87  87  LEU LEU R . n 
A 1 88  LEU 88  88  88  LEU LEU R . n 
A 1 89  PHE 89  89  89  PHE PHE R . n 
A 1 90  LEU 90  90  90  LEU LEU R . n 
A 1 91  PRO 91  91  91  PRO PRO R . n 
A 1 92  LEU 92  92  92  LEU LEU R . n 
A 1 93  TYR 93  93  93  TYR TYR R . n 
A 1 94  ILE 94  94  94  ILE ILE R . n 
A 1 95  SER 95  95  95  SER SER R . n 
A 1 96  TYR 96  96  96  TYR TYR R . n 
A 1 97  VAL 97  97  97  VAL VAL R . n 
A 1 98  ALA 98  98  98  ALA ALA R . n 
A 1 99  MET 99  99  99  MET MET R . n 
A 1 100 ASN 100 100 100 ASN ASN R . n 
A 1 101 PHE 101 101 101 PHE PHE R . n 
A 1 102 HIS 102 102 102 HIS HIS R . n 
A 1 103 TRP 103 103 103 TRP TRP R . n 
A 1 104 PRO 104 104 104 PRO PRO R . n 
A 1 105 PHE 105 105 105 PHE PHE R . n 
A 1 106 GLY 106 106 106 GLY GLY R . n 
A 1 107 ILE 107 107 107 ILE ILE R . n 
A 1 108 TRP 108 108 108 TRP TRP R . n 
A 1 109 LEU 109 109 109 LEU LEU R . n 
A 1 110 CYS 110 110 110 CYS CYS R . n 
A 1 111 LYS 111 111 111 LYS LYS R . n 
A 1 112 ALA 112 112 112 ALA ALA R . n 
A 1 113 ASN 113 113 113 ASN ASN R . n 
A 1 114 SER 114 114 114 SER SER R . n 
A 1 115 PHE 115 115 115 PHE PHE R . n 
A 1 116 THR 116 116 116 THR THR R . n 
A 1 117 ALA 117 117 117 ALA ALA R . n 
A 1 118 GLN 118 118 118 GLN GLN R . n 
A 1 119 LEU 119 119 119 LEU LEU R . n 
A 1 120 ASN 120 120 120 ASN ASN R . n 
A 1 121 MET 121 121 121 MET MET R . n 
A 1 122 PHE 122 122 122 PHE PHE R . n 
A 1 123 ALA 123 123 123 ALA ALA R . n 
A 1 124 SER 124 124 124 SER SER R . n 
A 1 125 VAL 125 125 125 VAL VAL R . n 
A 1 126 PHE 126 126 126 PHE PHE R . n 
A 1 127 PHE 127 127 127 PHE PHE R . n 
A 1 128 LEU 128 128 128 LEU LEU R . n 
A 1 129 THR 129 129 129 THR THR R . n 
A 1 130 VAL 130 130 130 VAL VAL R . n 
A 1 131 ILE 131 131 131 ILE ILE R . n 
A 1 132 SER 132 132 132 SER SER R . n 
A 1 133 LEU 133 133 133 LEU LEU R . n 
A 1 134 ASP 134 134 134 ASP ASP R . n 
A 1 135 HIS 135 135 135 HIS HIS R . n 
A 1 136 TYR 136 136 136 TYR TYR R . n 
A 1 137 ILE 137 137 137 ILE ILE R . n 
A 1 138 HIS 138 138 138 HIS HIS R . n 
A 1 139 LEU 139 139 139 LEU LEU R . n 
A 1 140 ILE 140 140 140 ILE ILE R . n 
A 1 141 HIS 141 141 141 HIS HIS R . n 
A 1 142 PRO 142 142 142 PRO PRO R . n 
A 1 143 VAL 143 143 143 VAL VAL R . n 
A 1 144 LEU 144 144 144 LEU LEU R . n 
A 1 145 SER 145 145 145 SER SER R . n 
A 1 146 HIS 146 146 146 HIS HIS R . n 
A 1 147 ARG 147 147 147 ARG ARG R . n 
A 1 148 HIS 148 148 148 HIS HIS R . n 
A 1 149 ARG 149 149 149 ARG ARG R . n 
A 1 150 THR 150 150 150 THR THR R . n 
A 1 151 LEU 151 151 151 LEU LEU R . n 
A 1 152 LYS 152 152 152 LYS LYS R . n 
A 1 153 ASN 153 153 153 ASN ASN R . n 
A 1 154 SER 154 154 154 SER SER R . n 
A 1 155 LEU 155 155 155 LEU LEU R . n 
A 1 156 ILE 156 156 156 ILE ILE R . n 
A 1 157 VAL 157 157 157 VAL VAL R . n 
A 1 158 ILE 158 158 158 ILE ILE R . n 
A 1 159 ILE 159 159 159 ILE ILE R . n 
A 1 160 PHE 160 160 160 PHE PHE R . n 
A 1 161 ILE 161 161 161 ILE ILE R . n 
A 1 162 TRP 162 162 162 TRP TRP R . n 
A 1 163 LEU 163 163 163 LEU LEU R . n 
A 1 164 LEU 164 164 164 LEU LEU R . n 
A 1 165 ALA 165 165 165 ALA ALA R . n 
A 1 166 SER 166 166 166 SER SER R . n 
A 1 167 LEU 167 167 167 LEU LEU R . n 
A 1 168 ILE 168 168 168 ILE ILE R . n 
A 1 169 GLY 169 169 169 GLY GLY R . n 
A 1 170 GLY 170 170 170 GLY GLY R . n 
A 1 171 PRO 171 171 171 PRO PRO R . n 
A 1 172 ALA 172 172 172 ALA ALA R . n 
A 1 173 LEU 173 173 173 LEU LEU R . n 
A 1 174 TYR 174 174 174 TYR TYR R . n 
A 1 175 PHE 175 175 175 PHE PHE R . n 
A 1 176 ARG 176 176 176 ARG ARG R . n 
A 1 177 ASP 177 177 177 ASP ASP R . n 
A 1 178 THR 178 178 178 THR THR R . n 
A 1 179 VAL 179 179 179 VAL VAL R . n 
A 1 180 GLU 180 180 180 GLU GLU R . n 
A 1 181 PHE 181 181 181 PHE PHE R . n 
A 1 182 ASN 182 182 182 ASN ASN R . n 
A 1 183 ASN 183 183 183 ASN ASN R . n 
A 1 184 HIS 184 184 184 HIS HIS R . n 
A 1 185 THR 185 185 185 THR THR R . n 
A 1 186 LEU 186 186 186 LEU LEU R . n 
A 1 187 CYS 187 187 187 CYS CYS R . n 
A 1 188 TYR 188 188 188 TYR TYR R . n 
A 1 189 ASN 189 189 189 ASN ASN R . n 
A 1 190 ASN 190 190 190 ASN ASN R . n 
A 1 191 PHE 191 191 191 PHE PHE R . n 
A 1 192 GLN 192 192 192 GLN GLN R . n 
A 1 193 LYS 193 193 193 LYS LYS R . n 
A 1 194 HIS 194 194 194 HIS HIS R . n 
A 1 195 ASP 195 195 195 ASP ASP R . n 
A 1 196 PRO 196 196 196 PRO PRO R . n 
A 1 197 ASP 197 197 197 ASP ASP R . n 
A 1 198 LEU 198 198 198 LEU LEU R . n 
A 1 199 THR 199 199 199 THR THR R . n 
A 1 200 LEU 200 200 200 LEU LEU R . n 
A 1 201 ILE 201 201 201 ILE ILE R . n 
A 1 202 ARG 202 202 202 ARG ARG R . n 
A 1 203 HIS 203 203 203 HIS HIS R . n 
A 1 204 HIS 204 204 204 HIS HIS R . n 
A 1 205 VAL 205 205 205 VAL VAL R . n 
A 1 206 LEU 206 206 206 LEU LEU R . n 
A 1 207 THR 207 207 207 THR THR R . n 
A 1 208 TRP 208 208 208 TRP TRP R . n 
A 1 209 VAL 209 209 209 VAL VAL R . n 
A 1 210 LYS 210 210 210 LYS LYS R . n 
A 1 211 PHE 211 211 211 PHE PHE R . n 
A 1 212 ILE 212 212 212 ILE ILE R . n 
A 1 213 ILE 213 213 213 ILE ILE R . n 
A 1 214 GLY 214 214 214 GLY GLY R . n 
A 1 215 TYR 215 215 215 TYR TYR R . n 
A 1 216 LEU 216 216 216 LEU LEU R . n 
A 1 217 PHE 217 217 217 PHE PHE R . n 
A 1 218 PRO 218 218 218 PRO PRO R . n 
A 1 219 LEU 219 219 219 LEU LEU R . n 
A 1 220 LEU 220 220 220 LEU LEU R . n 
A 1 221 THR 221 221 221 THR THR R . n 
A 1 222 MET 222 222 222 MET MET R . n 
A 1 223 SER 223 223 223 SER SER R . n 
A 1 224 ILE 224 224 224 ILE ILE R . n 
A 1 225 CYS 225 225 225 CYS CYS R . n 
A 1 226 TYR 226 226 226 TYR TYR R . n 
A 1 227 LEU 227 227 227 LEU LEU R . n 
A 1 228 CYS 228 228 228 CYS CYS R . n 
A 1 229 LEU 229 229 229 LEU LEU R . n 
A 1 230 ILE 230 230 230 ILE ILE R . n 
A 1 231 PHE 231 231 231 PHE PHE R . n 
A 1 232 LYS 232 232 232 LYS LYS R . n 
A 1 233 VAL 233 233 233 VAL VAL R . n 
A 1 234 LYS 234 234 234 LYS LYS R . n 
A 1 235 LYS 235 235 235 LYS LYS R . n 
A 1 236 ARG 236 236 236 ARG ARG R . n 
A 1 237 SER 237 237 237 SER SER R . n 
A 1 238 ILE 238 238 238 ILE ILE R . n 
A 1 239 LEU 239 239 239 LEU LEU R . n 
A 1 240 ILE 240 240 240 ILE ILE R . n 
A 1 241 SER 241 241 241 SER SER R . n 
A 1 242 SER 242 242 242 SER SER R . n 
A 1 243 ARG 243 243 243 ARG ARG R . n 
A 1 244 HIS 244 244 244 HIS HIS R . n 
A 1 245 PHE 245 245 245 PHE PHE R . n 
A 1 246 TRP 246 246 246 TRP TRP R . n 
A 1 247 THR 247 247 247 THR THR R . n 
A 1 248 ILE 248 248 248 ILE ILE R . n 
A 1 249 LEU 249 249 249 LEU LEU R . n 
A 1 250 VAL 250 250 250 VAL VAL R . n 
A 1 251 VAL 251 251 251 VAL VAL R . n 
A 1 252 VAL 252 252 252 VAL VAL R . n 
A 1 253 VAL 253 253 253 VAL VAL R . n 
A 1 254 ALA 254 254 254 ALA ALA R . n 
A 1 255 PHE 255 255 255 PHE PHE R . n 
A 1 256 VAL 256 256 256 VAL VAL R . n 
A 1 257 VAL 257 257 257 VAL VAL R . n 
A 1 258 CYS 258 258 258 CYS CYS R . n 
A 1 259 TRP 259 259 259 TRP TRP R . n 
A 1 260 THR 260 260 260 THR THR R . n 
A 1 261 PRO 261 261 261 PRO PRO R . n 
A 1 262 TYR 262 262 262 TYR TYR R . n 
A 1 263 HIS 263 263 263 HIS HIS R . n 
A 1 264 LEU 264 264 264 LEU LEU R . n 
A 1 265 PHE 265 265 265 PHE PHE R . n 
A 1 266 SER 266 266 266 SER SER R . n 
A 1 267 ILE 267 267 267 ILE ILE R . n 
A 1 268 TRP 268 268 268 TRP TRP R . n 
A 1 269 GLU 269 269 269 GLU GLU R . n 
A 1 270 LEU 270 270 270 LEU LEU R . n 
A 1 271 THR 271 271 271 THR THR R . n 
A 1 272 ILE 272 272 272 ILE ILE R . n 
A 1 273 HIS 273 273 273 HIS HIS R . n 
A 1 274 HIS 274 274 274 HIS HIS R . n 
A 1 275 ASN 275 275 275 ASN ASN R . n 
A 1 276 SER 276 276 276 SER SER R . n 
A 1 277 TYR 277 277 277 TYR TYR R . n 
A 1 278 SER 278 278 278 SER SER R . n 
A 1 279 HIS 279 279 279 HIS HIS R . n 
A 1 280 HIS 280 280 280 HIS HIS R . n 
A 1 281 VAL 281 281 281 VAL VAL R . n 
A 1 282 MET 282 282 282 MET MET R . n 
A 1 283 GLN 283 283 283 GLN GLN R . n 
A 1 284 ALA 284 284 284 ALA ALA R . n 
A 1 285 GLY 285 285 285 GLY GLY R . n 
A 1 286 ILE 286 286 286 ILE ILE R . n 
A 1 287 PRO 287 287 287 PRO PRO R . n 
A 1 288 LEU 288 288 288 LEU LEU R . n 
A 1 289 SER 289 289 289 SER SER R . n 
A 1 290 THR 290 290 290 THR THR R . n 
A 1 291 GLY 291 291 291 GLY GLY R . n 
A 1 292 LEU 292 292 292 LEU LEU R . n 
A 1 293 ALA 293 293 293 ALA ALA R . n 
A 1 294 PHE 294 294 294 PHE PHE R . n 
A 1 295 LEU 295 295 295 LEU LEU R . n 
A 1 296 ASN 296 296 296 ASN ASN R . n 
A 1 297 SER 297 297 297 SER SER R . n 
A 1 298 CYS 298 298 298 CYS CYS R . n 
A 1 299 LEU 299 299 299 LEU LEU R . n 
A 1 300 ASN 300 300 300 ASN ASN R . n 
A 1 301 PRO 301 301 301 PRO PRO R . n 
A 1 302 ILE 302 302 302 ILE ILE R . n 
A 1 303 LEU 303 303 303 LEU LEU R . n 
A 1 304 TYR 304 304 304 TYR TYR R . n 
A 1 305 VAL 305 305 305 VAL VAL R . n 
A 1 306 LEU 306 306 306 LEU LEU R . n 
A 1 307 ILE 307 307 307 ILE ILE R . n 
A 1 308 SER 308 308 308 SER SER R . n 
A 1 309 LYS 309 309 309 LYS LYS R . n 
A 1 310 LYS 310 310 310 LYS LYS R . n 
A 1 311 PHE 311 311 311 PHE PHE R . n 
A 1 312 GLN 312 312 312 GLN GLN R . n 
A 1 313 ALA 313 313 313 ALA ALA R . n 
A 1 314 ARG 314 314 314 ARG ARG R . n 
A 1 315 PHE 315 315 315 PHE PHE R . n 
A 1 316 ARG 316 316 ?   ?   ?   R . n 
A 1 317 SER 317 317 ?   ?   ?   R . n 
A 1 318 SER 318 318 ?   ?   ?   R . n 
A 1 319 VAL 319 319 ?   ?   ?   R . n 
A 1 320 ALA 320 320 ?   ?   ?   R . n 
A 1 321 GLU 321 321 ?   ?   ?   R . n 
A 1 322 ILE 322 322 ?   ?   ?   R . n 
A 1 323 GLU 323 323 ?   ?   ?   R . n 
A 1 324 PHE 324 324 ?   ?   ?   R . n 
A 1 325 LEU 325 325 ?   ?   ?   R . n 
A 1 326 GLU 326 326 ?   ?   ?   R . n 
A 1 327 VAL 327 327 ?   ?   ?   R . n 
A 1 328 LEU 328 328 ?   ?   ?   R . n 
A 1 329 PHE 329 329 ?   ?   ?   R . n 
A 1 330 GLN 330 330 ?   ?   ?   R . n 
A 1 331 GLY 331 331 ?   ?   ?   R . n 
A 1 332 PRO 332 332 ?   ?   ?   R . n 
A 1 333 TRP 333 333 ?   ?   ?   R . n 
A 1 334 SER 334 334 ?   ?   ?   R . n 
A 1 335 HIS 335 335 ?   ?   ?   R . n 
A 1 336 PRO 336 336 ?   ?   ?   R . n 
A 1 337 GLN 337 337 ?   ?   ?   R . n 
A 1 338 PHE 338 338 ?   ?   ?   R . n 
A 1 339 GLU 339 339 ?   ?   ?   R . n 
A 1 340 LYS 340 340 ?   ?   ?   R . n 
A 1 341 GLY 341 341 ?   ?   ?   R . n 
A 1 342 GLY 342 342 ?   ?   ?   R . n 
A 1 343 GLY 343 343 ?   ?   ?   R . n 
A 1 344 SER 344 344 ?   ?   ?   R . n 
A 1 345 GLY 345 345 ?   ?   ?   R . n 
A 1 346 GLY 346 346 ?   ?   ?   R . n 
A 1 347 GLY 347 347 ?   ?   ?   R . n 
A 1 348 SER 348 348 ?   ?   ?   R . n 
A 1 349 GLY 349 349 ?   ?   ?   R . n 
A 1 350 GLY 350 350 ?   ?   ?   R . n 
A 1 351 SER 351 351 ?   ?   ?   R . n 
A 1 352 ALA 352 352 ?   ?   ?   R . n 
A 1 353 TRP 353 353 ?   ?   ?   R . n 
A 1 354 SER 354 354 ?   ?   ?   R . n 
A 1 355 HIS 355 355 ?   ?   ?   R . n 
A 1 356 PRO 356 356 ?   ?   ?   R . n 
A 1 357 GLN 357 357 ?   ?   ?   R . n 
A 1 358 PHE 358 358 ?   ?   ?   R . n 
A 1 359 GLU 359 359 ?   ?   ?   R . n 
A 1 360 LYS 360 360 ?   ?   ?   R . n 
A 1 361 ASP 361 361 ?   ?   ?   R . n 
A 1 362 TYR 362 362 ?   ?   ?   R . n 
A 1 363 LYS 363 363 ?   ?   ?   R . n 
A 1 364 ASP 364 364 ?   ?   ?   R . n 
A 1 365 ASP 365 365 ?   ?   ?   R . n 
A 1 366 ASP 366 366 ?   ?   ?   R . n 
A 1 367 ASP 367 367 ?   ?   ?   R . n 
A 1 368 LYS 368 368 ?   ?   ?   R . n 
B 2 1   GLU 1   21  ?   ?   ?   L . n 
B 2 2   LEU 2   22  ?   ?   ?   L . n 
B 2 3   THR 3   23  23  THR THR L . n 
B 2 4   GLU 4   24  24  GLU GLU L . n 
B 2 5   ALA 5   25  25  ALA ALA L . n 
B 2 6   GLN 6   26  26  GLN GLN L . n 
B 2 7   ARG 7   27  27  ARG ARG L . n 
B 2 8   ARG 8   28  28  ARG ARG L . n 
B 2 9   GLY 9   29  29  GLY GLY L . n 
B 2 10  LEU 10  30  30  LEU LEU L . n 
B 2 11  GLN 11  31  31  GLN GLN L . n 
B 2 12  VAL 12  32  32  VAL VAL L . n 
B 2 13  ALA 13  33  33  ALA ALA L . n 
B 2 14  LEU 14  34  34  LEU LEU L . n 
B 2 15  GLU 15  35  35  GLU GLU L . n 
B 2 16  GLU 16  36  36  GLU GLU L . n 
B 2 17  PHE 17  37  37  PHE PHE L . n 
B 2 18  HIS 18  38  38  HIS HIS L . n 
B 2 19  LYS 19  39  39  LYS LYS L . n 
B 2 20  HIS 20  40  40  HIS HIS L . n 
B 2 21  PRO 21  41  41  PRO PRO L . n 
B 2 22  PRO 22  42  ?   ?   ?   L . n 
B 2 23  VAL 23  43  ?   ?   ?   L . n 
B 2 24  GLN 24  44  ?   ?   ?   L . n 
B 2 25  TRP 25  45  45  TRP TRP L . n 
B 2 26  ALA 26  46  46  ALA ALA L . n 
B 2 27  PHE 27  47  47  PHE PHE L . n 
B 2 28  GLN 28  48  48  GLN GLN L . n 
B 2 29  GLU 29  49  49  GLU GLU L . n 
B 2 30  THR 30  50  50  THR THR L . n 
B 2 31  SER 31  51  51  SER SER L . n 
B 2 32  VAL 32  52  52  VAL VAL L . n 
B 2 33  GLU 33  53  53  GLU GLU L . n 
B 2 34  SER 34  54  54  SER SER L . n 
B 2 35  ALA 35  55  55  ALA ALA L . n 
B 2 36  VAL 36  56  56  VAL VAL L . n 
B 2 37  ASP 37  57  57  ASP ASP L . n 
B 2 38  THR 38  58  58  THR THR L . n 
B 2 39  PRO 39  59  59  PRO PRO L . n 
B 2 40  PHE 40  60  60  PHE PHE L . n 
B 2 41  PRO 41  61  61  PRO PRO L . n 
B 2 42  ALA 42  62  62  ALA ALA L . n 
B 2 43  GLY 43  63  63  GLY GLY L . n 
B 2 44  ILE 44  64  64  ILE ILE L . n 
B 2 45  PHE 45  65  65  PHE PHE L . n 
B 2 46  VAL 46  66  66  VAL VAL L . n 
B 2 47  ARG 47  67  67  ARG ARG L . n 
B 2 48  LEU 48  68  68  LEU LEU L . n 
B 2 49  GLU 49  69  69  GLU GLU L . n 
B 2 50  PHE 50  70  70  PHE PHE L . n 
B 2 51  LYS 51  71  71  LYS LYS L . n 
B 2 52  LEU 52  72  72  LEU LEU L . n 
B 2 53  GLN 53  73  73  GLN GLN L . n 
B 2 54  GLN 54  74  74  GLN GLN L . n 
B 2 55  THR 55  75  75  THR THR L . n 
B 2 56  SER 56  76  76  SER SER L . n 
B 2 57  CYS 57  77  77  CYS CYS L . n 
B 2 58  ARG 58  78  78  ARG ARG L . n 
B 2 59  LYS 59  79  79  LYS LYS L . n 
B 2 60  ARG 60  80  80  ARG ARG L . n 
B 2 61  ASP 61  81  81  ASP ASP L . n 
B 2 62  TRP 62  82  82  TRP TRP L . n 
B 2 63  LYS 63  83  83  LYS LYS L . n 
B 2 64  LYS 64  84  84  LYS LYS L . n 
B 2 65  PRO 65  85  85  PRO PRO L . n 
B 2 66  GLU 66  86  86  GLU GLU L . n 
B 2 67  CYS 67  87  87  CYS CYS L . n 
B 2 68  LYS 68  88  88  LYS LYS L . n 
B 2 69  VAL 69  89  89  VAL VAL L . n 
B 2 70  ARG 70  90  90  ARG ARG L . n 
B 2 71  PRO 71  91  ?   ?   ?   L . n 
B 2 72  ASN 72  92  ?   ?   ?   L . n 
B 2 73  GLY 73  93  ?   ?   ?   L . n 
B 2 74  ARG 74  94  ?   ?   ?   L . n 
B 2 75  LYS 75  95  ?   ?   ?   L . n 
B 2 76  ARG 76  96  ?   ?   ?   L . n 
B 2 77  LYS 77  97  97  LYS LYS L . n 
B 2 78  CYS 78  98  98  CYS CYS L . n 
B 2 79  LEU 79  99  99  LEU LEU L . n 
B 2 80  ALA 80  100 100 ALA ALA L . n 
B 2 81  CYS 81  101 101 CYS CYS L . n 
B 2 82  ILE 82  102 102 ILE ILE L . n 
B 2 83  LYS 83  103 103 LYS LYS L . n 
B 2 84  LEU 84  104 ?   ?   ?   L . n 
B 2 85  GLY 85  105 ?   ?   ?   L . n 
B 2 86  SER 86  106 ?   ?   ?   L . n 
B 2 87  GLU 87  107 ?   ?   ?   L . n 
B 2 88  ASP 88  108 ?   ?   ?   L . n 
B 2 89  LYS 89  109 109 LYS LYS L . n 
B 2 90  VAL 90  110 110 VAL VAL L . n 
B 2 91  LEU 91  111 111 LEU LEU L . n 
B 2 92  GLY 92  112 112 GLY GLY L . n 
B 2 93  ARG 93  113 113 ARG ARG L . n 
B 2 94  LEU 94  114 114 LEU LEU L . n 
B 2 95  VAL 95  115 115 VAL VAL L . n 
B 2 96  HIS 96  116 116 HIS HIS L . n 
B 2 97  CYS 97  117 117 CYS CYS L . n 
B 2 98  PRO 98  118 ?   ?   ?   L . n 
B 2 99  ILE 99  119 ?   ?   ?   L . n 
B 2 100 GLU 100 120 ?   ?   ?   L . n 
B 2 101 THR 101 121 ?   ?   ?   L . n 
B 2 102 GLN 102 122 ?   ?   ?   L . n 
B 2 103 VAL 103 123 ?   ?   ?   L . n 
B 2 104 LEU 104 124 ?   ?   ?   L . n 
B 2 105 ARG 105 125 ?   ?   ?   L . n 
B 2 106 GLU 106 126 ?   ?   ?   L . n 
B 2 107 ALA 107 127 ?   ?   ?   L . n 
B 2 108 GLU 108 128 ?   ?   ?   L . n 
B 2 109 GLU 109 129 ?   ?   ?   L . n 
B 2 110 HIS 110 130 ?   ?   ?   L . n 
B 2 111 GLN 111 131 ?   ?   ?   L . n 
B 2 112 GLU 112 132 ?   ?   ?   L . n 
B 2 113 THR 113 133 133 THR THR L . n 
B 2 114 GLN 114 134 134 GLN GLN L . n 
B 2 115 CYS 115 135 135 CYS CYS L . n 
B 2 116 LEU 116 136 136 LEU LEU L . n 
B 2 117 ARG 117 137 137 ARG ARG L . n 
B 2 118 VAL 118 138 138 VAL VAL L . n 
B 2 119 GLN 119 139 139 GLN GLN L . n 
B 2 120 ARG 120 140 140 ARG ARG L . n 
B 2 121 ALA 121 141 141 ALA ALA L . n 
B 2 122 GLY 122 142 142 GLY GLY L . n 
B 2 123 GLU 123 143 ?   ?   ?   L . n 
B 2 124 ASP 124 144 ?   ?   ?   L . n 
B 2 125 PRO 125 145 ?   ?   ?   L . n 
B 2 126 HIS 126 146 146 HIS HIS L . n 
B 2 127 SER 127 147 147 SER SER L . n 
B 2 128 PHE 128 148 148 PHE PHE L . n 
B 2 129 TYR 129 149 149 TYR TYR L . n 
B 2 130 PHE 130 150 150 PHE PHE L . n 
B 2 131 PRO 131 151 151 PRO PRO L . n 
B 2 132 GLY 132 152 152 GLY GLY L . n 
B 2 133 GLN 133 153 153 GLN GLN L . n 
B 2 134 PHE 134 154 154 PHE PHE L . n 
B 2 135 ALA 135 155 155 ALA ALA L . n 
B 2 136 PHE 136 156 156 PHE PHE L . n 
B 2 137 SER 137 157 157 SER SER L . n 
C 3 1   MET 1   1   ?   ?   ?   A . n 
C 3 2   GLY 2   2   ?   ?   ?   A . n 
C 3 3   CYS 3   3   ?   ?   ?   A . n 
C 3 4   THR 4   4   ?   ?   ?   A . n 
C 3 5   LEU 5   5   ?   ?   ?   A . n 
C 3 6   SER 6   6   6   SER SER A . n 
C 3 7   ALA 7   7   7   ALA ALA A . n 
C 3 8   GLU 8   8   8   GLU GLU A . n 
C 3 9   ASP 9   9   9   ASP ASP A . n 
C 3 10  LYS 10  10  10  LYS LYS A . n 
C 3 11  ALA 11  11  11  ALA ALA A . n 
C 3 12  ALA 12  12  12  ALA ALA A . n 
C 3 13  VAL 13  13  13  VAL VAL A . n 
C 3 14  GLU 14  14  14  GLU GLU A . n 
C 3 15  ARG 15  15  15  ARG ARG A . n 
C 3 16  SER 16  16  16  SER SER A . n 
C 3 17  LYS 17  17  17  LYS LYS A . n 
C 3 18  MET 18  18  18  MET MET A . n 
C 3 19  ILE 19  19  19  ILE ILE A . n 
C 3 20  ASP 20  20  20  ASP ASP A . n 
C 3 21  ARG 21  21  21  ARG ARG A . n 
C 3 22  ASN 22  22  22  ASN ASN A . n 
C 3 23  LEU 23  23  23  LEU LEU A . n 
C 3 24  ARG 24  24  24  ARG ARG A . n 
C 3 25  GLU 25  25  25  GLU GLU A . n 
C 3 26  ASP 26  26  26  ASP ASP A . n 
C 3 27  GLY 27  27  27  GLY GLY A . n 
C 3 28  GLU 28  28  28  GLU GLU A . n 
C 3 29  LYS 29  29  29  LYS LYS A . n 
C 3 30  ALA 30  30  30  ALA ALA A . n 
C 3 31  ALA 31  31  31  ALA ALA A . n 
C 3 32  ARG 32  32  32  ARG ARG A . n 
C 3 33  GLU 33  33  33  GLU GLU A . n 
C 3 34  VAL 34  34  34  VAL VAL A . n 
C 3 35  LYS 35  35  35  LYS LYS A . n 
C 3 36  LEU 36  36  36  LEU LEU A . n 
C 3 37  LEU 37  37  37  LEU LEU A . n 
C 3 38  LEU 38  38  38  LEU LEU A . n 
C 3 39  LEU 39  39  39  LEU LEU A . n 
C 3 40  GLY 40  40  40  GLY GLY A . n 
C 3 41  ALA 41  41  41  ALA ALA A . n 
C 3 42  GLY 42  42  42  GLY GLY A . n 
C 3 43  GLU 43  43  43  GLU GLU A . n 
C 3 44  SER 44  44  44  SER SER A . n 
C 3 45  GLY 45  45  45  GLY GLY A . n 
C 3 46  LYS 46  46  46  LYS LYS A . n 
C 3 47  CYS 47  47  47  CYS CYS A . n 
C 3 48  THR 48  48  48  THR THR A . n 
C 3 49  ILE 49  49  49  ILE ILE A . n 
C 3 50  VAL 50  50  50  VAL VAL A . n 
C 3 51  LYS 51  51  51  LYS LYS A . n 
C 3 52  GLN 52  52  52  GLN GLN A . n 
C 3 53  MET 53  53  53  MET MET A . n 
C 3 54  LYS 54  54  ?   ?   ?   A . n 
C 3 55  ILE 55  55  ?   ?   ?   A . n 
C 3 56  ILE 56  56  ?   ?   ?   A . n 
C 3 57  HIS 57  57  ?   ?   ?   A . n 
C 3 58  GLU 58  58  ?   ?   ?   A . n 
C 3 59  ALA 59  59  ?   ?   ?   A . n 
C 3 60  GLY 60  60  ?   ?   ?   A . n 
C 3 61  TYR 61  61  ?   ?   ?   A . n 
C 3 62  SER 62  62  ?   ?   ?   A . n 
C 3 63  GLU 63  63  ?   ?   ?   A . n 
C 3 64  GLU 64  64  ?   ?   ?   A . n 
C 3 65  GLU 65  65  ?   ?   ?   A . n 
C 3 66  CYS 66  66  ?   ?   ?   A . n 
C 3 67  LYS 67  67  ?   ?   ?   A . n 
C 3 68  GLN 68  68  ?   ?   ?   A . n 
C 3 69  TYR 69  69  ?   ?   ?   A . n 
C 3 70  LYS 70  70  ?   ?   ?   A . n 
C 3 71  ALA 71  71  ?   ?   ?   A . n 
C 3 72  VAL 72  72  ?   ?   ?   A . n 
C 3 73  VAL 73  73  ?   ?   ?   A . n 
C 3 74  TYR 74  74  ?   ?   ?   A . n 
C 3 75  SER 75  75  ?   ?   ?   A . n 
C 3 76  ASN 76  76  ?   ?   ?   A . n 
C 3 77  THR 77  77  ?   ?   ?   A . n 
C 3 78  ILE 78  78  ?   ?   ?   A . n 
C 3 79  GLN 79  79  ?   ?   ?   A . n 
C 3 80  SER 80  80  ?   ?   ?   A . n 
C 3 81  ILE 81  81  ?   ?   ?   A . n 
C 3 82  ILE 82  82  ?   ?   ?   A . n 
C 3 83  ALA 83  83  ?   ?   ?   A . n 
C 3 84  ILE 84  84  ?   ?   ?   A . n 
C 3 85  ILE 85  85  ?   ?   ?   A . n 
C 3 86  ARG 86  86  ?   ?   ?   A . n 
C 3 87  ALA 87  87  ?   ?   ?   A . n 
C 3 88  MET 88  88  ?   ?   ?   A . n 
C 3 89  GLY 89  89  ?   ?   ?   A . n 
C 3 90  ARG 90  90  ?   ?   ?   A . n 
C 3 91  LEU 91  91  ?   ?   ?   A . n 
C 3 92  LYS 92  92  ?   ?   ?   A . n 
C 3 93  ILE 93  93  ?   ?   ?   A . n 
C 3 94  ASP 94  94  ?   ?   ?   A . n 
C 3 95  PHE 95  95  ?   ?   ?   A . n 
C 3 96  GLY 96  96  ?   ?   ?   A . n 
C 3 97  ASP 97  97  ?   ?   ?   A . n 
C 3 98  SER 98  98  ?   ?   ?   A . n 
C 3 99  ALA 99  99  ?   ?   ?   A . n 
C 3 100 ARG 100 100 ?   ?   ?   A . n 
C 3 101 ALA 101 101 ?   ?   ?   A . n 
C 3 102 ASP 102 102 ?   ?   ?   A . n 
C 3 103 ASP 103 103 ?   ?   ?   A . n 
C 3 104 ALA 104 104 ?   ?   ?   A . n 
C 3 105 ARG 105 105 ?   ?   ?   A . n 
C 3 106 GLN 106 106 ?   ?   ?   A . n 
C 3 107 LEU 107 107 ?   ?   ?   A . n 
C 3 108 PHE 108 108 ?   ?   ?   A . n 
C 3 109 VAL 109 109 ?   ?   ?   A . n 
C 3 110 LEU 110 110 ?   ?   ?   A . n 
C 3 111 ALA 111 111 ?   ?   ?   A . n 
C 3 112 GLY 112 112 ?   ?   ?   A . n 
C 3 113 ALA 113 113 ?   ?   ?   A . n 
C 3 114 ALA 114 114 ?   ?   ?   A . n 
C 3 115 GLU 115 115 ?   ?   ?   A . n 
C 3 116 GLU 116 116 ?   ?   ?   A . n 
C 3 117 GLY 117 117 ?   ?   ?   A . n 
C 3 118 PHE 118 118 ?   ?   ?   A . n 
C 3 119 MET 119 119 ?   ?   ?   A . n 
C 3 120 THR 120 120 ?   ?   ?   A . n 
C 3 121 ALA 121 121 ?   ?   ?   A . n 
C 3 122 GLU 122 122 ?   ?   ?   A . n 
C 3 123 LEU 123 123 ?   ?   ?   A . n 
C 3 124 ALA 124 124 ?   ?   ?   A . n 
C 3 125 GLY 125 125 ?   ?   ?   A . n 
C 3 126 VAL 126 126 ?   ?   ?   A . n 
C 3 127 ILE 127 127 ?   ?   ?   A . n 
C 3 128 LYS 128 128 ?   ?   ?   A . n 
C 3 129 ARG 129 129 ?   ?   ?   A . n 
C 3 130 LEU 130 130 ?   ?   ?   A . n 
C 3 131 TRP 131 131 ?   ?   ?   A . n 
C 3 132 LYS 132 132 ?   ?   ?   A . n 
C 3 133 ASP 133 133 ?   ?   ?   A . n 
C 3 134 SER 134 134 ?   ?   ?   A . n 
C 3 135 GLY 135 135 ?   ?   ?   A . n 
C 3 136 VAL 136 136 ?   ?   ?   A . n 
C 3 137 GLN 137 137 ?   ?   ?   A . n 
C 3 138 ALA 138 138 ?   ?   ?   A . n 
C 3 139 CYS 139 139 ?   ?   ?   A . n 
C 3 140 PHE 140 140 ?   ?   ?   A . n 
C 3 141 ASN 141 141 ?   ?   ?   A . n 
C 3 142 ARG 142 142 ?   ?   ?   A . n 
C 3 143 SER 143 143 ?   ?   ?   A . n 
C 3 144 ARG 144 144 ?   ?   ?   A . n 
C 3 145 GLU 145 145 ?   ?   ?   A . n 
C 3 146 TYR 146 146 ?   ?   ?   A . n 
C 3 147 GLN 147 147 ?   ?   ?   A . n 
C 3 148 LEU 148 148 ?   ?   ?   A . n 
C 3 149 ASN 149 149 ?   ?   ?   A . n 
C 3 150 ASP 150 150 ?   ?   ?   A . n 
C 3 151 SER 151 151 ?   ?   ?   A . n 
C 3 152 ALA 152 152 ?   ?   ?   A . n 
C 3 153 ALA 153 153 ?   ?   ?   A . n 
C 3 154 TYR 154 154 ?   ?   ?   A . n 
C 3 155 TYR 155 155 ?   ?   ?   A . n 
C 3 156 LEU 156 156 ?   ?   ?   A . n 
C 3 157 ASN 157 157 ?   ?   ?   A . n 
C 3 158 ASP 158 158 ?   ?   ?   A . n 
C 3 159 LEU 159 159 ?   ?   ?   A . n 
C 3 160 ASP 160 160 ?   ?   ?   A . n 
C 3 161 ARG 161 161 ?   ?   ?   A . n 
C 3 162 ILE 162 162 ?   ?   ?   A . n 
C 3 163 ALA 163 163 ?   ?   ?   A . n 
C 3 164 GLN 164 164 ?   ?   ?   A . n 
C 3 165 PRO 165 165 ?   ?   ?   A . n 
C 3 166 ASN 166 166 ?   ?   ?   A . n 
C 3 167 TYR 167 167 ?   ?   ?   A . n 
C 3 168 ILE 168 168 ?   ?   ?   A . n 
C 3 169 PRO 169 169 ?   ?   ?   A . n 
C 3 170 THR 170 170 ?   ?   ?   A . n 
C 3 171 GLN 171 171 ?   ?   ?   A . n 
C 3 172 GLN 172 172 ?   ?   ?   A . n 
C 3 173 ASP 173 173 ?   ?   ?   A . n 
C 3 174 VAL 174 174 ?   ?   ?   A . n 
C 3 175 LEU 175 175 ?   ?   ?   A . n 
C 3 176 ARG 176 176 ?   ?   ?   A . n 
C 3 177 THR 177 177 ?   ?   ?   A . n 
C 3 178 ARG 178 178 ?   ?   ?   A . n 
C 3 179 VAL 179 179 ?   ?   ?   A . n 
C 3 180 LYS 180 180 ?   ?   ?   A . n 
C 3 181 THR 181 181 ?   ?   ?   A . n 
C 3 182 THR 182 182 182 THR THR A . n 
C 3 183 GLY 183 183 183 GLY GLY A . n 
C 3 184 ILE 184 184 184 ILE ILE A . n 
C 3 185 VAL 185 185 185 VAL VAL A . n 
C 3 186 GLU 186 186 186 GLU GLU A . n 
C 3 187 THR 187 187 187 THR THR A . n 
C 3 188 HIS 188 188 188 HIS HIS A . n 
C 3 189 PHE 189 189 189 PHE PHE A . n 
C 3 190 THR 190 190 190 THR THR A . n 
C 3 191 PHE 191 191 191 PHE PHE A . n 
C 3 192 LYS 192 192 192 LYS LYS A . n 
C 3 193 ASP 193 193 193 ASP ASP A . n 
C 3 194 LEU 194 194 194 LEU LEU A . n 
C 3 195 HIS 195 195 195 HIS HIS A . n 
C 3 196 PHE 196 196 196 PHE PHE A . n 
C 3 197 LYS 197 197 197 LYS LYS A . n 
C 3 198 MET 198 198 198 MET MET A . n 
C 3 199 PHE 199 199 199 PHE PHE A . n 
C 3 200 ASP 200 200 200 ASP ASP A . n 
C 3 201 VAL 201 201 201 VAL VAL A . n 
C 3 202 THR 202 202 202 THR THR A . n 
C 3 203 ALA 203 203 203 ALA ALA A . n 
C 3 204 GLN 204 204 204 GLN GLN A . n 
C 3 205 ARG 205 205 205 ARG ARG A . n 
C 3 206 SER 206 206 206 SER SER A . n 
C 3 207 GLU 207 207 207 GLU GLU A . n 
C 3 208 ARG 208 208 208 ARG ARG A . n 
C 3 209 LYS 209 209 209 LYS LYS A . n 
C 3 210 LYS 210 210 210 LYS LYS A . n 
C 3 211 TRP 211 211 211 TRP TRP A . n 
C 3 212 ILE 212 212 212 ILE ILE A . n 
C 3 213 HIS 213 213 213 HIS HIS A . n 
C 3 214 CYS 214 214 214 CYS CYS A . n 
C 3 215 PHE 215 215 215 PHE PHE A . n 
C 3 216 GLU 216 216 216 GLU GLU A . n 
C 3 217 GLY 217 217 217 GLY GLY A . n 
C 3 218 VAL 218 218 218 VAL VAL A . n 
C 3 219 THR 219 219 219 THR THR A . n 
C 3 220 ALA 220 220 220 ALA ALA A . n 
C 3 221 ILE 221 221 221 ILE ILE A . n 
C 3 222 ILE 222 222 222 ILE ILE A . n 
C 3 223 PHE 223 223 223 PHE PHE A . n 
C 3 224 CYS 224 224 224 CYS CYS A . n 
C 3 225 VAL 225 225 225 VAL VAL A . n 
C 3 226 ALA 226 226 226 ALA ALA A . n 
C 3 227 LEU 227 227 227 LEU LEU A . n 
C 3 228 SER 228 228 228 SER SER A . n 
C 3 229 ASP 229 229 229 ASP ASP A . n 
C 3 230 TYR 230 230 230 TYR TYR A . n 
C 3 231 ASP 231 231 231 ASP ASP A . n 
C 3 232 LEU 232 232 232 LEU LEU A . n 
C 3 233 VAL 233 233 233 VAL VAL A . n 
C 3 234 LEU 234 234 234 LEU LEU A . n 
C 3 235 ALA 235 235 ?   ?   ?   A . n 
C 3 236 GLU 236 236 ?   ?   ?   A . n 
C 3 237 ASP 237 237 ?   ?   ?   A . n 
C 3 238 GLU 238 238 ?   ?   ?   A . n 
C 3 239 GLU 239 239 ?   ?   ?   A . n 
C 3 240 MET 240 240 ?   ?   ?   A . n 
C 3 241 ASN 241 241 241 ASN ASN A . n 
C 3 242 ARG 242 242 242 ARG ARG A . n 
C 3 243 MET 243 243 243 MET MET A . n 
C 3 244 HIS 244 244 244 HIS HIS A . n 
C 3 245 ALA 245 245 245 ALA ALA A . n 
C 3 246 SER 246 246 246 SER SER A . n 
C 3 247 MET 247 247 247 MET MET A . n 
C 3 248 LYS 248 248 248 LYS LYS A . n 
C 3 249 LEU 249 249 249 LEU LEU A . n 
C 3 250 PHE 250 250 250 PHE PHE A . n 
C 3 251 ASP 251 251 251 ASP ASP A . n 
C 3 252 SER 252 252 252 SER SER A . n 
C 3 253 ILE 253 253 253 ILE ILE A . n 
C 3 254 CYS 254 254 254 CYS CYS A . n 
C 3 255 ASN 255 255 255 ASN ASN A . n 
C 3 256 ASN 256 256 256 ASN ASN A . n 
C 3 257 LYS 257 257 257 LYS LYS A . n 
C 3 258 TRP 258 258 258 TRP TRP A . n 
C 3 259 PHE 259 259 259 PHE PHE A . n 
C 3 260 THR 260 260 260 THR THR A . n 
C 3 261 ASP 261 261 261 ASP ASP A . n 
C 3 262 THR 262 262 262 THR THR A . n 
C 3 263 SER 263 263 263 SER SER A . n 
C 3 264 ILE 264 264 264 ILE ILE A . n 
C 3 265 ILE 265 265 265 ILE ILE A . n 
C 3 266 LEU 266 266 266 LEU LEU A . n 
C 3 267 PHE 267 267 267 PHE PHE A . n 
C 3 268 LEU 268 268 268 LEU LEU A . n 
C 3 269 ASN 269 269 269 ASN ASN A . n 
C 3 270 LYS 270 270 270 LYS LYS A . n 
C 3 271 LYS 271 271 271 LYS LYS A . n 
C 3 272 ASP 272 272 272 ASP ASP A . n 
C 3 273 LEU 273 273 273 LEU LEU A . n 
C 3 274 PHE 274 274 274 PHE PHE A . n 
C 3 275 GLU 275 275 275 GLU GLU A . n 
C 3 276 GLU 276 276 276 GLU GLU A . n 
C 3 277 LYS 277 277 277 LYS LYS A . n 
C 3 278 ILE 278 278 278 ILE ILE A . n 
C 3 279 LYS 279 279 279 LYS LYS A . n 
C 3 280 LYS 280 280 280 LYS LYS A . n 
C 3 281 SER 281 281 281 SER SER A . n 
C 3 282 PRO 282 282 282 PRO PRO A . n 
C 3 283 LEU 283 283 283 LEU LEU A . n 
C 3 284 THR 284 284 284 THR THR A . n 
C 3 285 ILE 285 285 285 ILE ILE A . n 
C 3 286 CYS 286 286 286 CYS CYS A . n 
C 3 287 TYR 287 287 287 TYR TYR A . n 
C 3 288 PRO 288 288 288 PRO PRO A . n 
C 3 289 GLU 289 289 289 GLU GLU A . n 
C 3 290 TYR 290 290 290 TYR TYR A . n 
C 3 291 ALA 291 291 291 ALA ALA A . n 
C 3 292 GLY 292 292 292 GLY GLY A . n 
C 3 293 SER 293 293 293 SER SER A . n 
C 3 294 ASN 294 294 294 ASN ASN A . n 
C 3 295 THR 295 295 295 THR THR A . n 
C 3 296 TYR 296 296 296 TYR TYR A . n 
C 3 297 GLU 297 297 297 GLU GLU A . n 
C 3 298 GLU 298 298 298 GLU GLU A . n 
C 3 299 ALA 299 299 299 ALA ALA A . n 
C 3 300 ALA 300 300 300 ALA ALA A . n 
C 3 301 ALA 301 301 301 ALA ALA A . n 
C 3 302 TYR 302 302 302 TYR TYR A . n 
C 3 303 ILE 303 303 303 ILE ILE A . n 
C 3 304 GLN 304 304 304 GLN GLN A . n 
C 3 305 CYS 305 305 305 CYS CYS A . n 
C 3 306 GLN 306 306 306 GLN GLN A . n 
C 3 307 PHE 307 307 307 PHE PHE A . n 
C 3 308 GLU 308 308 308 GLU GLU A . n 
C 3 309 ASP 309 309 309 ASP ASP A . n 
C 3 310 LEU 310 310 310 LEU LEU A . n 
C 3 311 ASN 311 311 311 ASN ASN A . n 
C 3 312 LYS 312 312 312 LYS LYS A . n 
C 3 313 ARG 313 313 313 ARG ARG A . n 
C 3 314 LYS 314 314 314 LYS LYS A . n 
C 3 315 ASP 315 315 315 ASP ASP A . n 
C 3 316 THR 316 316 316 THR THR A . n 
C 3 317 LYS 317 317 317 LYS LYS A . n 
C 3 318 GLU 318 318 318 GLU GLU A . n 
C 3 319 ILE 319 319 319 ILE ILE A . n 
C 3 320 TYR 320 320 320 TYR TYR A . n 
C 3 321 THR 321 321 321 THR THR A . n 
C 3 322 HIS 322 322 322 HIS HIS A . n 
C 3 323 PHE 323 323 323 PHE PHE A . n 
C 3 324 THR 324 324 324 THR THR A . n 
C 3 325 CYS 325 325 ?   ?   ?   A . n 
C 3 326 SER 326 326 ?   ?   ?   A . n 
C 3 327 THR 327 327 ?   ?   ?   A . n 
C 3 328 ASP 328 328 ?   ?   ?   A . n 
C 3 329 THR 329 329 329 THR THR A . n 
C 3 330 LYS 330 330 330 LYS LYS A . n 
C 3 331 ASN 331 331 331 ASN ASN A . n 
C 3 332 VAL 332 332 332 VAL VAL A . n 
C 3 333 GLN 333 333 333 GLN GLN A . n 
C 3 334 PHE 334 334 334 PHE PHE A . n 
C 3 335 VAL 335 335 335 VAL VAL A . n 
C 3 336 PHE 336 336 336 PHE PHE A . n 
C 3 337 ASP 337 337 337 ASP ASP A . n 
C 3 338 ALA 338 338 338 ALA ALA A . n 
C 3 339 VAL 339 339 339 VAL VAL A . n 
C 3 340 THR 340 340 340 THR THR A . n 
C 3 341 ASP 341 341 341 ASP ASP A . n 
C 3 342 VAL 342 342 342 VAL VAL A . n 
C 3 343 ILE 343 343 343 ILE ILE A . n 
C 3 344 ILE 344 344 344 ILE ILE A . n 
C 3 345 LYS 345 345 345 LYS LYS A . n 
C 3 346 ASN 346 346 346 ASN ASN A . n 
C 3 347 ASN 347 347 347 ASN ASN A . n 
C 3 348 LEU 348 348 348 LEU LEU A . n 
C 3 349 LYS 349 349 349 LYS LYS A . n 
C 3 350 ASP 350 350 350 ASP ASP A . n 
C 3 351 CYS 351 351 351 CYS CYS A . n 
C 3 352 GLY 352 352 352 GLY GLY A . n 
C 3 353 LEU 353 353 353 LEU LEU A . n 
C 3 354 PHE 354 354 354 PHE PHE A . n 
D 4 1   MET 1   1   ?   ?   ?   B . n 
D 4 2   SER 2   2   ?   ?   ?   B . n 
D 4 3   GLU 3   3   ?   ?   ?   B . n 
D 4 4   LEU 4   4   ?   ?   ?   B . n 
D 4 5   ASP 5   5   ?   ?   ?   B . n 
D 4 6   GLN 6   6   ?   ?   ?   B . n 
D 4 7   LEU 7   7   7   LEU LEU B . n 
D 4 8   ARG 8   8   8   ARG ARG B . n 
D 4 9   GLN 9   9   9   GLN GLN B . n 
D 4 10  GLU 10  10  10  GLU GLU B . n 
D 4 11  ALA 11  11  11  ALA ALA B . n 
D 4 12  GLU 12  12  12  GLU GLU B . n 
D 4 13  GLN 13  13  13  GLN GLN B . n 
D 4 14  LEU 14  14  14  LEU LEU B . n 
D 4 15  LYS 15  15  15  LYS LYS B . n 
D 4 16  ASN 16  16  16  ASN ASN B . n 
D 4 17  GLN 17  17  17  GLN GLN B . n 
D 4 18  ILE 18  18  18  ILE ILE B . n 
D 4 19  ARG 19  19  19  ARG ARG B . n 
D 4 20  ASP 20  20  20  ASP ASP B . n 
D 4 21  ALA 21  21  21  ALA ALA B . n 
D 4 22  ARG 22  22  22  ARG ARG B . n 
D 4 23  LYS 23  23  23  LYS LYS B . n 
D 4 24  ALA 24  24  24  ALA ALA B . n 
D 4 25  CYS 25  25  25  CYS CYS B . n 
D 4 26  ALA 26  26  26  ALA ALA B . n 
D 4 27  ASP 27  27  27  ASP ASP B . n 
D 4 28  ALA 28  28  28  ALA ALA B . n 
D 4 29  THR 29  29  29  THR THR B . n 
D 4 30  LEU 30  30  30  LEU LEU B . n 
D 4 31  SER 31  31  31  SER SER B . n 
D 4 32  GLN 32  32  32  GLN GLN B . n 
D 4 33  ILE 33  33  33  ILE ILE B . n 
D 4 34  THR 34  34  34  THR THR B . n 
D 4 35  ASN 35  35  35  ASN ASN B . n 
D 4 36  ASN 36  36  36  ASN ASN B . n 
D 4 37  ILE 37  37  37  ILE ILE B . n 
D 4 38  ASP 38  38  38  ASP ASP B . n 
D 4 39  PRO 39  39  39  PRO PRO B . n 
D 4 40  VAL 40  40  40  VAL VAL B . n 
D 4 41  GLY 41  41  41  GLY GLY B . n 
D 4 42  ARG 42  42  42  ARG ARG B . n 
D 4 43  ILE 43  43  43  ILE ILE B . n 
D 4 44  GLN 44  44  44  GLN GLN B . n 
D 4 45  MET 45  45  45  MET MET B . n 
D 4 46  ARG 46  46  46  ARG ARG B . n 
D 4 47  THR 47  47  47  THR THR B . n 
D 4 48  ARG 48  48  48  ARG ARG B . n 
D 4 49  ARG 49  49  49  ARG ARG B . n 
D 4 50  THR 50  50  50  THR THR B . n 
D 4 51  LEU 51  51  51  LEU LEU B . n 
D 4 52  ARG 52  52  52  ARG ARG B . n 
D 4 53  GLY 53  53  53  GLY GLY B . n 
D 4 54  HIS 54  54  54  HIS HIS B . n 
D 4 55  LEU 55  55  55  LEU LEU B . n 
D 4 56  ALA 56  56  56  ALA ALA B . n 
D 4 57  LYS 57  57  57  LYS LYS B . n 
D 4 58  ILE 58  58  58  ILE ILE B . n 
D 4 59  TYR 59  59  59  TYR TYR B . n 
D 4 60  ALA 60  60  60  ALA ALA B . n 
D 4 61  MET 61  61  61  MET MET B . n 
D 4 62  HIS 62  62  62  HIS HIS B . n 
D 4 63  TRP 63  63  63  TRP TRP B . n 
D 4 64  GLY 64  64  64  GLY GLY B . n 
D 4 65  THR 65  65  65  THR THR B . n 
D 4 66  ASP 66  66  66  ASP ASP B . n 
D 4 67  SER 67  67  67  SER SER B . n 
D 4 68  ARG 68  68  68  ARG ARG B . n 
D 4 69  LEU 69  69  69  LEU LEU B . n 
D 4 70  LEU 70  70  70  LEU LEU B . n 
D 4 71  VAL 71  71  71  VAL VAL B . n 
D 4 72  SER 72  72  72  SER SER B . n 
D 4 73  ALA 73  73  73  ALA ALA B . n 
D 4 74  SER 74  74  74  SER SER B . n 
D 4 75  GLN 75  75  75  GLN GLN B . n 
D 4 76  ASP 76  76  76  ASP ASP B . n 
D 4 77  GLY 77  77  77  GLY GLY B . n 
D 4 78  LYS 78  78  78  LYS LYS B . n 
D 4 79  LEU 79  79  79  LEU LEU B . n 
D 4 80  ILE 80  80  80  ILE ILE B . n 
D 4 81  ILE 81  81  81  ILE ILE B . n 
D 4 82  TRP 82  82  82  TRP TRP B . n 
D 4 83  ASP 83  83  83  ASP ASP B . n 
D 4 84  SER 84  84  84  SER SER B . n 
D 4 85  TYR 85  85  85  TYR TYR B . n 
D 4 86  THR 86  86  86  THR THR B . n 
D 4 87  THR 87  87  87  THR THR B . n 
D 4 88  ASN 88  88  88  ASN ASN B . n 
D 4 89  LYS 89  89  89  LYS LYS B . n 
D 4 90  VAL 90  90  90  VAL VAL B . n 
D 4 91  HIS 91  91  91  HIS HIS B . n 
D 4 92  ALA 92  92  92  ALA ALA B . n 
D 4 93  ILE 93  93  93  ILE ILE B . n 
D 4 94  PRO 94  94  94  PRO PRO B . n 
D 4 95  LEU 95  95  95  LEU LEU B . n 
D 4 96  ARG 96  96  96  ARG ARG B . n 
D 4 97  SER 97  97  97  SER SER B . n 
D 4 98  SER 98  98  98  SER SER B . n 
D 4 99  TRP 99  99  99  TRP TRP B . n 
D 4 100 VAL 100 100 100 VAL VAL B . n 
D 4 101 MET 101 101 101 MET MET B . n 
D 4 102 THR 102 102 102 THR THR B . n 
D 4 103 CYS 103 103 103 CYS CYS B . n 
D 4 104 ALA 104 104 104 ALA ALA B . n 
D 4 105 TYR 105 105 105 TYR TYR B . n 
D 4 106 ALA 106 106 106 ALA ALA B . n 
D 4 107 PRO 107 107 107 PRO PRO B . n 
D 4 108 SER 108 108 108 SER SER B . n 
D 4 109 GLY 109 109 109 GLY GLY B . n 
D 4 110 ASN 110 110 110 ASN ASN B . n 
D 4 111 TYR 111 111 111 TYR TYR B . n 
D 4 112 VAL 112 112 112 VAL VAL B . n 
D 4 113 ALA 113 113 113 ALA ALA B . n 
D 4 114 CYS 114 114 114 CYS CYS B . n 
D 4 115 GLY 115 115 115 GLY GLY B . n 
D 4 116 GLY 116 116 116 GLY GLY B . n 
D 4 117 LEU 117 117 117 LEU LEU B . n 
D 4 118 ASP 118 118 118 ASP ASP B . n 
D 4 119 ASN 119 119 119 ASN ASN B . n 
D 4 120 ILE 120 120 120 ILE ILE B . n 
D 4 121 CYS 121 121 121 CYS CYS B . n 
D 4 122 SER 122 122 122 SER SER B . n 
D 4 123 ILE 123 123 123 ILE ILE B . n 
D 4 124 TYR 124 124 124 TYR TYR B . n 
D 4 125 ASN 125 125 125 ASN ASN B . n 
D 4 126 LEU 126 126 126 LEU LEU B . n 
D 4 127 LYS 127 127 127 LYS LYS B . n 
D 4 128 THR 128 128 128 THR THR B . n 
D 4 129 ARG 129 129 ?   ?   ?   B . n 
D 4 130 GLU 130 130 ?   ?   ?   B . n 
D 4 131 GLY 131 131 ?   ?   ?   B . n 
D 4 132 ASN 132 132 ?   ?   ?   B . n 
D 4 133 VAL 133 133 133 VAL VAL B . n 
D 4 134 ARG 134 134 134 ARG ARG B . n 
D 4 135 VAL 135 135 135 VAL VAL B . n 
D 4 136 SER 136 136 136 SER SER B . n 
D 4 137 ARG 137 137 137 ARG ARG B . n 
D 4 138 GLU 138 138 138 GLU GLU B . n 
D 4 139 LEU 139 139 139 LEU LEU B . n 
D 4 140 ALA 140 140 140 ALA ALA B . n 
D 4 141 GLY 141 141 141 GLY GLY B . n 
D 4 142 HIS 142 142 142 HIS HIS B . n 
D 4 143 THR 143 143 143 THR THR B . n 
D 4 144 GLY 144 144 144 GLY GLY B . n 
D 4 145 TYR 145 145 145 TYR TYR B . n 
D 4 146 LEU 146 146 146 LEU LEU B . n 
D 4 147 SER 147 147 147 SER SER B . n 
D 4 148 CYS 148 148 148 CYS CYS B . n 
D 4 149 CYS 149 149 149 CYS CYS B . n 
D 4 150 ARG 150 150 150 ARG ARG B . n 
D 4 151 PHE 151 151 151 PHE PHE B . n 
D 4 152 LEU 152 152 152 LEU LEU B . n 
D 4 153 ASP 153 153 153 ASP ASP B . n 
D 4 154 ASP 154 154 154 ASP ASP B . n 
D 4 155 ASN 155 155 155 ASN ASN B . n 
D 4 156 GLN 156 156 156 GLN GLN B . n 
D 4 157 ILE 157 157 157 ILE ILE B . n 
D 4 158 VAL 158 158 158 VAL VAL B . n 
D 4 159 THR 159 159 159 THR THR B . n 
D 4 160 SER 160 160 160 SER SER B . n 
D 4 161 SER 161 161 161 SER SER B . n 
D 4 162 GLY 162 162 162 GLY GLY B . n 
D 4 163 ASP 163 163 163 ASP ASP B . n 
D 4 164 THR 164 164 164 THR THR B . n 
D 4 165 THR 165 165 165 THR THR B . n 
D 4 166 CYS 166 166 166 CYS CYS B . n 
D 4 167 ALA 167 167 167 ALA ALA B . n 
D 4 168 LEU 168 168 168 LEU LEU B . n 
D 4 169 TRP 169 169 169 TRP TRP B . n 
D 4 170 ASP 170 170 170 ASP ASP B . n 
D 4 171 ILE 171 171 171 ILE ILE B . n 
D 4 172 GLU 172 172 172 GLU GLU B . n 
D 4 173 THR 173 173 173 THR THR B . n 
D 4 174 GLY 174 174 174 GLY GLY B . n 
D 4 175 GLN 175 175 175 GLN GLN B . n 
D 4 176 GLN 176 176 176 GLN GLN B . n 
D 4 177 THR 177 177 177 THR THR B . n 
D 4 178 THR 178 178 178 THR THR B . n 
D 4 179 THR 179 179 179 THR THR B . n 
D 4 180 PHE 180 180 180 PHE PHE B . n 
D 4 181 THR 181 181 181 THR THR B . n 
D 4 182 GLY 182 182 182 GLY GLY B . n 
D 4 183 HIS 183 183 183 HIS HIS B . n 
D 4 184 THR 184 184 184 THR THR B . n 
D 4 185 GLY 185 185 185 GLY GLY B . n 
D 4 186 ASP 186 186 186 ASP ASP B . n 
D 4 187 VAL 187 187 187 VAL VAL B . n 
D 4 188 MET 188 188 188 MET MET B . n 
D 4 189 SER 189 189 189 SER SER B . n 
D 4 190 LEU 190 190 190 LEU LEU B . n 
D 4 191 SER 191 191 191 SER SER B . n 
D 4 192 LEU 192 192 192 LEU LEU B . n 
D 4 193 ALA 193 193 193 ALA ALA B . n 
D 4 194 PRO 194 194 194 PRO PRO B . n 
D 4 195 ASP 195 195 195 ASP ASP B . n 
D 4 196 THR 196 196 196 THR THR B . n 
D 4 197 ARG 197 197 197 ARG ARG B . n 
D 4 198 LEU 198 198 198 LEU LEU B . n 
D 4 199 PHE 199 199 199 PHE PHE B . n 
D 4 200 VAL 200 200 200 VAL VAL B . n 
D 4 201 SER 201 201 201 SER SER B . n 
D 4 202 GLY 202 202 202 GLY GLY B . n 
D 4 203 ALA 203 203 203 ALA ALA B . n 
D 4 204 CYS 204 204 204 CYS CYS B . n 
D 4 205 ASP 205 205 205 ASP ASP B . n 
D 4 206 ALA 206 206 206 ALA ALA B . n 
D 4 207 SER 207 207 207 SER SER B . n 
D 4 208 ALA 208 208 208 ALA ALA B . n 
D 4 209 LYS 209 209 209 LYS LYS B . n 
D 4 210 LEU 210 210 210 LEU LEU B . n 
D 4 211 TRP 211 211 211 TRP TRP B . n 
D 4 212 ASP 212 212 212 ASP ASP B . n 
D 4 213 VAL 213 213 213 VAL VAL B . n 
D 4 214 ARG 214 214 214 ARG ARG B . n 
D 4 215 GLU 215 215 215 GLU GLU B . n 
D 4 216 GLY 216 216 216 GLY GLY B . n 
D 4 217 MET 217 217 217 MET MET B . n 
D 4 218 CYS 218 218 218 CYS CYS B . n 
D 4 219 ARG 219 219 219 ARG ARG B . n 
D 4 220 GLN 220 220 220 GLN GLN B . n 
D 4 221 THR 221 221 221 THR THR B . n 
D 4 222 PHE 222 222 222 PHE PHE B . n 
D 4 223 THR 223 223 223 THR THR B . n 
D 4 224 GLY 224 224 224 GLY GLY B . n 
D 4 225 HIS 225 225 225 HIS HIS B . n 
D 4 226 GLU 226 226 226 GLU GLU B . n 
D 4 227 SER 227 227 227 SER SER B . n 
D 4 228 ASP 228 228 228 ASP ASP B . n 
D 4 229 ILE 229 229 229 ILE ILE B . n 
D 4 230 ASN 230 230 230 ASN ASN B . n 
D 4 231 ALA 231 231 231 ALA ALA B . n 
D 4 232 ILE 232 232 232 ILE ILE B . n 
D 4 233 CYS 233 233 233 CYS CYS B . n 
D 4 234 PHE 234 234 234 PHE PHE B . n 
D 4 235 PHE 235 235 235 PHE PHE B . n 
D 4 236 PRO 236 236 236 PRO PRO B . n 
D 4 237 ASN 237 237 237 ASN ASN B . n 
D 4 238 GLY 238 238 238 GLY GLY B . n 
D 4 239 ASN 239 239 239 ASN ASN B . n 
D 4 240 ALA 240 240 240 ALA ALA B . n 
D 4 241 PHE 241 241 241 PHE PHE B . n 
D 4 242 ALA 242 242 242 ALA ALA B . n 
D 4 243 THR 243 243 243 THR THR B . n 
D 4 244 GLY 244 244 244 GLY GLY B . n 
D 4 245 SER 245 245 245 SER SER B . n 
D 4 246 ASP 246 246 246 ASP ASP B . n 
D 4 247 ASP 247 247 247 ASP ASP B . n 
D 4 248 ALA 248 248 248 ALA ALA B . n 
D 4 249 THR 249 249 249 THR THR B . n 
D 4 250 CYS 250 250 250 CYS CYS B . n 
D 4 251 ARG 251 251 251 ARG ARG B . n 
D 4 252 LEU 252 252 252 LEU LEU B . n 
D 4 253 PHE 253 253 253 PHE PHE B . n 
D 4 254 ASP 254 254 254 ASP ASP B . n 
D 4 255 LEU 255 255 255 LEU LEU B . n 
D 4 256 ARG 256 256 256 ARG ARG B . n 
D 4 257 ALA 257 257 257 ALA ALA B . n 
D 4 258 ASP 258 258 258 ASP ASP B . n 
D 4 259 GLN 259 259 259 GLN GLN B . n 
D 4 260 GLU 260 260 260 GLU GLU B . n 
D 4 261 LEU 261 261 261 LEU LEU B . n 
D 4 262 MET 262 262 262 MET MET B . n 
D 4 263 THR 263 263 263 THR THR B . n 
D 4 264 TYR 264 264 264 TYR TYR B . n 
D 4 265 SER 265 265 265 SER SER B . n 
D 4 266 HIS 266 266 266 HIS HIS B . n 
D 4 267 ASP 267 267 267 ASP ASP B . n 
D 4 268 ASN 268 268 268 ASN ASN B . n 
D 4 269 ILE 269 269 269 ILE ILE B . n 
D 4 270 ILE 270 270 270 ILE ILE B . n 
D 4 271 CYS 271 271 271 CYS CYS B . n 
D 4 272 GLY 272 272 272 GLY GLY B . n 
D 4 273 ILE 273 273 273 ILE ILE B . n 
D 4 274 THR 274 274 274 THR THR B . n 
D 4 275 SER 275 275 275 SER SER B . n 
D 4 276 VAL 276 276 276 VAL VAL B . n 
D 4 277 SER 277 277 277 SER SER B . n 
D 4 278 PHE 278 278 278 PHE PHE B . n 
D 4 279 SER 279 279 279 SER SER B . n 
D 4 280 LYS 280 280 280 LYS LYS B . n 
D 4 281 SER 281 281 281 SER SER B . n 
D 4 282 GLY 282 282 282 GLY GLY B . n 
D 4 283 ARG 283 283 283 ARG ARG B . n 
D 4 284 LEU 284 284 284 LEU LEU B . n 
D 4 285 LEU 285 285 285 LEU LEU B . n 
D 4 286 LEU 286 286 286 LEU LEU B . n 
D 4 287 ALA 287 287 287 ALA ALA B . n 
D 4 288 GLY 288 288 288 GLY GLY B . n 
D 4 289 TYR 289 289 289 TYR TYR B . n 
D 4 290 ASP 290 290 290 ASP ASP B . n 
D 4 291 ASP 291 291 291 ASP ASP B . n 
D 4 292 PHE 292 292 292 PHE PHE B . n 
D 4 293 ASN 293 293 293 ASN ASN B . n 
D 4 294 CYS 294 294 294 CYS CYS B . n 
D 4 295 ASN 295 295 295 ASN ASN B . n 
D 4 296 VAL 296 296 296 VAL VAL B . n 
D 4 297 TRP 297 297 297 TRP TRP B . n 
D 4 298 ASP 298 298 298 ASP ASP B . n 
D 4 299 ALA 299 299 299 ALA ALA B . n 
D 4 300 LEU 300 300 300 LEU LEU B . n 
D 4 301 LYS 301 301 301 LYS LYS B . n 
D 4 302 ALA 302 302 302 ALA ALA B . n 
D 4 303 ASP 303 303 303 ASP ASP B . n 
D 4 304 ARG 304 304 304 ARG ARG B . n 
D 4 305 ALA 305 305 305 ALA ALA B . n 
D 4 306 GLY 306 306 306 GLY GLY B . n 
D 4 307 VAL 307 307 307 VAL VAL B . n 
D 4 308 LEU 308 308 308 LEU LEU B . n 
D 4 309 ALA 309 309 309 ALA ALA B . n 
D 4 310 GLY 310 310 310 GLY GLY B . n 
D 4 311 HIS 311 311 311 HIS HIS B . n 
D 4 312 ASP 312 312 312 ASP ASP B . n 
D 4 313 ASN 313 313 313 ASN ASN B . n 
D 4 314 ARG 314 314 314 ARG ARG B . n 
D 4 315 VAL 315 315 315 VAL VAL B . n 
D 4 316 SER 316 316 316 SER SER B . n 
D 4 317 CYS 317 317 317 CYS CYS B . n 
D 4 318 LEU 318 318 318 LEU LEU B . n 
D 4 319 GLY 319 319 319 GLY GLY B . n 
D 4 320 VAL 320 320 320 VAL VAL B . n 
D 4 321 THR 321 321 321 THR THR B . n 
D 4 322 ASP 322 322 322 ASP ASP B . n 
D 4 323 ASP 323 323 323 ASP ASP B . n 
D 4 324 GLY 324 324 324 GLY GLY B . n 
D 4 325 MET 325 325 325 MET MET B . n 
D 4 326 ALA 326 326 326 ALA ALA B . n 
D 4 327 VAL 327 327 327 VAL VAL B . n 
D 4 328 ALA 328 328 328 ALA ALA B . n 
D 4 329 THR 329 329 329 THR THR B . n 
D 4 330 GLY 330 330 330 GLY GLY B . n 
D 4 331 SER 331 331 331 SER SER B . n 
D 4 332 TRP 332 332 332 TRP TRP B . n 
D 4 333 ASP 333 333 333 ASP ASP B . n 
D 4 334 SER 334 334 334 SER SER B . n 
D 4 335 PHE 335 335 335 PHE PHE B . n 
D 4 336 LEU 336 336 336 LEU LEU B . n 
D 4 337 LYS 337 337 337 LYS LYS B . n 
D 4 338 ILE 338 338 338 ILE ILE B . n 
D 4 339 TRP 339 339 339 TRP TRP B . n 
D 4 340 ASN 340 340 340 ASN ASN B . n 
E 5 1   MET 1   1   ?   ?   ?   C . n 
E 5 2   ALA 2   2   ?   ?   ?   C . n 
E 5 3   SER 3   3   ?   ?   ?   C . n 
E 5 4   ASN 4   4   ?   ?   ?   C . n 
E 5 5   ASN 5   5   ?   ?   ?   C . n 
E 5 6   THR 6   6   ?   ?   ?   C . n 
E 5 7   ALA 7   7   ?   ?   ?   C . n 
E 5 8   SER 8   8   ?   ?   ?   C . n 
E 5 9   ILE 9   9   ?   ?   ?   C . n 
E 5 10  ALA 10  10  ?   ?   ?   C . n 
E 5 11  GLN 11  11  ?   ?   ?   C . n 
E 5 12  ALA 12  12  12  ALA ALA C . n 
E 5 13  ARG 13  13  13  ARG ARG C . n 
E 5 14  LYS 14  14  14  LYS LYS C . n 
E 5 15  LEU 15  15  15  LEU LEU C . n 
E 5 16  VAL 16  16  16  VAL VAL C . n 
E 5 17  GLU 17  17  17  GLU GLU C . n 
E 5 18  GLN 18  18  18  GLN GLN C . n 
E 5 19  LEU 19  19  19  LEU LEU C . n 
E 5 20  LYS 20  20  20  LYS LYS C . n 
E 5 21  MET 21  21  21  MET MET C . n 
E 5 22  GLU 22  22  22  GLU GLU C . n 
E 5 23  ALA 23  23  23  ALA ALA C . n 
E 5 24  ASN 24  24  24  ASN ASN C . n 
E 5 25  ILE 25  25  25  ILE ILE C . n 
E 5 26  ASP 26  26  26  ASP ASP C . n 
E 5 27  ARG 27  27  27  ARG ARG C . n 
E 5 28  ILE 28  28  28  ILE ILE C . n 
E 5 29  LYS 29  29  29  LYS LYS C . n 
E 5 30  VAL 30  30  30  VAL VAL C . n 
E 5 31  SER 31  31  31  SER SER C . n 
E 5 32  LYS 32  32  32  LYS LYS C . n 
E 5 33  ALA 33  33  33  ALA ALA C . n 
E 5 34  ALA 34  34  34  ALA ALA C . n 
E 5 35  ALA 35  35  35  ALA ALA C . n 
E 5 36  ASP 36  36  36  ASP ASP C . n 
E 5 37  LEU 37  37  37  LEU LEU C . n 
E 5 38  MET 38  38  38  MET MET C . n 
E 5 39  ALA 39  39  39  ALA ALA C . n 
E 5 40  TYR 40  40  40  TYR TYR C . n 
E 5 41  CYS 41  41  41  CYS CYS C . n 
E 5 42  GLU 42  42  42  GLU GLU C . n 
E 5 43  ALA 43  43  43  ALA ALA C . n 
E 5 44  HIS 44  44  44  HIS HIS C . n 
E 5 45  ALA 45  45  45  ALA ALA C . n 
E 5 46  LYS 46  46  46  LYS LYS C . n 
E 5 47  GLU 47  47  47  GLU GLU C . n 
E 5 48  ASP 48  48  48  ASP ASP C . n 
E 5 49  PRO 49  49  49  PRO PRO C . n 
E 5 50  LEU 50  50  50  LEU LEU C . n 
E 5 51  LEU 51  51  51  LEU LEU C . n 
E 5 52  THR 52  52  52  THR THR C . n 
E 5 53  PRO 53  53  53  PRO PRO C . n 
E 5 54  VAL 54  54  54  VAL VAL C . n 
E 5 55  PRO 55  55  55  PRO PRO C . n 
E 5 56  ALA 56  56  56  ALA ALA C . n 
E 5 57  SER 57  57  57  SER SER C . n 
E 5 58  GLU 58  58  58  GLU GLU C . n 
E 5 59  ASN 59  59  59  ASN ASN C . n 
E 5 60  PRO 60  60  60  PRO PRO C . n 
E 5 61  PHE 61  61  61  PHE PHE C . n 
E 5 62  ARG 62  62  62  ARG ARG C . n 
E 5 63  GLU 63  63  ?   ?   ?   C . n 
E 5 64  LYS 64  64  ?   ?   ?   C . n 
E 5 65  LYS 65  65  ?   ?   ?   C . n 
E 5 66  PHE 66  66  ?   ?   ?   C . n 
E 5 67  PHE 67  67  ?   ?   ?   C . n 
E 5 68  CYS 68  68  ?   ?   ?   C . n 
E 5 69  ALA 69  69  ?   ?   ?   C . n 
E 5 70  ILE 70  70  ?   ?   ?   C . n 
E 5 71  LEU 71  71  ?   ?   ?   C . n 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 R TYR 17  ? CG  ? A TYR 17  CG  
2   1 Y 1 R TYR 17  ? CD1 ? A TYR 17  CD1 
3   1 Y 1 R TYR 17  ? CD2 ? A TYR 17  CD2 
4   1 Y 1 R TYR 17  ? CE1 ? A TYR 17  CE1 
5   1 Y 1 R TYR 17  ? CE2 ? A TYR 17  CE2 
6   1 Y 1 R TYR 17  ? CZ  ? A TYR 17  CZ  
7   1 Y 1 R TYR 17  ? OH  ? A TYR 17  OH  
8   1 Y 1 R ASP 27  ? CG  ? A ASP 27  CG  
9   1 Y 1 R ASP 27  ? OD1 ? A ASP 27  OD1 
10  1 Y 1 R ASP 27  ? OD2 ? A ASP 27  OD2 
11  1 Y 1 R TRP 61  ? CG  ? A TRP 61  CG  
12  1 Y 1 R TRP 61  ? CD1 ? A TRP 61  CD1 
13  1 Y 1 R TRP 61  ? CD2 ? A TRP 61  CD2 
14  1 Y 1 R TRP 61  ? NE1 ? A TRP 61  NE1 
15  1 Y 1 R TRP 61  ? CE2 ? A TRP 61  CE2 
16  1 Y 1 R TRP 61  ? CE3 ? A TRP 61  CE3 
17  1 Y 1 R TRP 61  ? CZ2 ? A TRP 61  CZ2 
18  1 Y 1 R TRP 61  ? CZ3 ? A TRP 61  CZ3 
19  1 Y 1 R TRP 61  ? CH2 ? A TRP 61  CH2 
20  1 Y 1 R TRP 67  ? CG  ? A TRP 67  CG  
21  1 Y 1 R TRP 67  ? CD1 ? A TRP 67  CD1 
22  1 Y 1 R TRP 67  ? CD2 ? A TRP 67  CD2 
23  1 Y 1 R TRP 67  ? NE1 ? A TRP 67  NE1 
24  1 Y 1 R TRP 67  ? CE2 ? A TRP 67  CE2 
25  1 Y 1 R TRP 67  ? CE3 ? A TRP 67  CE3 
26  1 Y 1 R TRP 67  ? CZ2 ? A TRP 67  CZ2 
27  1 Y 1 R TRP 67  ? CZ3 ? A TRP 67  CZ3 
28  1 Y 1 R TRP 67  ? CH2 ? A TRP 67  CH2 
29  1 Y 1 R LYS 68  ? CG  ? A LYS 68  CG  
30  1 Y 1 R LYS 68  ? CD  ? A LYS 68  CD  
31  1 Y 1 R LYS 68  ? CE  ? A LYS 68  CE  
32  1 Y 1 R LYS 68  ? NZ  ? A LYS 68  NZ  
33  1 Y 1 R TYR 174 ? CG  ? A TYR 174 CG  
34  1 Y 1 R TYR 174 ? CD1 ? A TYR 174 CD1 
35  1 Y 1 R TYR 174 ? CD2 ? A TYR 174 CD2 
36  1 Y 1 R TYR 174 ? CE1 ? A TYR 174 CE1 
37  1 Y 1 R TYR 174 ? CE2 ? A TYR 174 CE2 
38  1 Y 1 R TYR 174 ? CZ  ? A TYR 174 CZ  
39  1 Y 1 R TYR 174 ? OH  ? A TYR 174 OH  
40  1 Y 1 R GLN 192 ? CG  ? A GLN 192 CG  
41  1 Y 1 R GLN 192 ? CD  ? A GLN 192 CD  
42  1 Y 1 R GLN 192 ? OE1 ? A GLN 192 OE1 
43  1 Y 1 R GLN 192 ? NE2 ? A GLN 192 NE2 
44  1 Y 1 R LYS 193 ? CG  ? A LYS 193 CG  
45  1 Y 1 R LYS 193 ? CD  ? A LYS 193 CD  
46  1 Y 1 R LYS 193 ? CE  ? A LYS 193 CE  
47  1 Y 1 R LYS 193 ? NZ  ? A LYS 193 NZ  
48  1 Y 1 R ASP 195 ? CG  ? A ASP 195 CG  
49  1 Y 1 R ASP 195 ? OD1 ? A ASP 195 OD1 
50  1 Y 1 R ASP 195 ? OD2 ? A ASP 195 OD2 
51  1 Y 1 R ASP 197 ? CG  ? A ASP 197 CG  
52  1 Y 1 R ASP 197 ? OD1 ? A ASP 197 OD1 
53  1 Y 1 R ASP 197 ? OD2 ? A ASP 197 OD2 
54  1 Y 1 R THR 199 ? OG1 ? A THR 199 OG1 
55  1 Y 1 R THR 199 ? CG2 ? A THR 199 CG2 
56  1 Y 1 R LEU 200 ? CG  ? A LEU 200 CG  
57  1 Y 1 R LEU 200 ? CD1 ? A LEU 200 CD1 
58  1 Y 1 R LEU 200 ? CD2 ? A LEU 200 CD2 
59  1 Y 1 R LYS 235 ? CG  ? A LYS 235 CG  
60  1 Y 1 R LYS 235 ? CD  ? A LYS 235 CD  
61  1 Y 1 R LYS 235 ? CE  ? A LYS 235 CE  
62  1 Y 1 R LYS 235 ? NZ  ? A LYS 235 NZ  
63  1 Y 1 R ILE 272 ? CG1 ? A ILE 272 CG1 
64  1 Y 1 R ILE 272 ? CG2 ? A ILE 272 CG2 
65  1 Y 1 R ILE 272 ? CD1 ? A ILE 272 CD1 
66  1 Y 1 R HIS 273 ? CG  ? A HIS 273 CG  
67  1 Y 1 R HIS 273 ? ND1 ? A HIS 273 ND1 
68  1 Y 1 R HIS 273 ? CD2 ? A HIS 273 CD2 
69  1 Y 1 R HIS 273 ? CE1 ? A HIS 273 CE1 
70  1 Y 1 R HIS 273 ? NE2 ? A HIS 273 NE2 
71  1 Y 1 R HIS 274 ? CG  ? A HIS 274 CG  
72  1 Y 1 R HIS 274 ? ND1 ? A HIS 274 ND1 
73  1 Y 1 R HIS 274 ? CD2 ? A HIS 274 CD2 
74  1 Y 1 R HIS 274 ? CE1 ? A HIS 274 CE1 
75  1 Y 1 R HIS 274 ? NE2 ? A HIS 274 NE2 
76  1 Y 1 R HIS 279 ? CG  ? A HIS 279 CG  
77  1 Y 1 R HIS 279 ? ND1 ? A HIS 279 ND1 
78  1 Y 1 R HIS 279 ? CD2 ? A HIS 279 CD2 
79  1 Y 1 R HIS 279 ? CE1 ? A HIS 279 CE1 
80  1 Y 1 R HIS 279 ? NE2 ? A HIS 279 NE2 
81  1 Y 1 R GLN 283 ? CG  ? A GLN 283 CG  
82  1 Y 1 R GLN 283 ? CD  ? A GLN 283 CD  
83  1 Y 1 R GLN 283 ? OE1 ? A GLN 283 OE1 
84  1 Y 1 R GLN 283 ? NE2 ? A GLN 283 NE2 
85  1 Y 1 R ASN 296 ? CG  ? A ASN 296 CG  
86  1 Y 1 R ASN 296 ? OD1 ? A ASN 296 OD1 
87  1 Y 1 R ASN 296 ? ND2 ? A ASN 296 ND2 
88  1 Y 1 L GLU 24  ? CG  ? B GLU 4   CG  
89  1 Y 1 L GLU 24  ? CD  ? B GLU 4   CD  
90  1 Y 1 L GLU 24  ? OE1 ? B GLU 4   OE1 
91  1 Y 1 L GLU 24  ? OE2 ? B GLU 4   OE2 
92  1 Y 1 L GLN 26  ? CG  ? B GLN 6   CG  
93  1 Y 1 L GLN 26  ? CD  ? B GLN 6   CD  
94  1 Y 1 L GLN 26  ? OE1 ? B GLN 6   OE1 
95  1 Y 1 L GLN 26  ? NE2 ? B GLN 6   NE2 
96  1 Y 1 L ARG 27  ? CG  ? B ARG 7   CG  
97  1 Y 1 L ARG 27  ? CD  ? B ARG 7   CD  
98  1 Y 1 L ARG 27  ? NE  ? B ARG 7   NE  
99  1 Y 1 L ARG 27  ? CZ  ? B ARG 7   CZ  
100 1 Y 1 L ARG 27  ? NH1 ? B ARG 7   NH1 
101 1 Y 1 L ARG 27  ? NH2 ? B ARG 7   NH2 
102 1 Y 1 L ARG 28  ? CG  ? B ARG 8   CG  
103 1 Y 1 L ARG 28  ? CD  ? B ARG 8   CD  
104 1 Y 1 L ARG 28  ? NE  ? B ARG 8   NE  
105 1 Y 1 L ARG 28  ? CZ  ? B ARG 8   CZ  
106 1 Y 1 L ARG 28  ? NH1 ? B ARG 8   NH1 
107 1 Y 1 L ARG 28  ? NH2 ? B ARG 8   NH2 
108 1 Y 1 L GLN 31  ? CG  ? B GLN 11  CG  
109 1 Y 1 L GLN 31  ? CD  ? B GLN 11  CD  
110 1 Y 1 L GLN 31  ? OE1 ? B GLN 11  OE1 
111 1 Y 1 L GLN 31  ? NE2 ? B GLN 11  NE2 
112 1 Y 1 L GLU 35  ? CG  ? B GLU 15  CG  
113 1 Y 1 L GLU 35  ? CD  ? B GLU 15  CD  
114 1 Y 1 L GLU 35  ? OE1 ? B GLU 15  OE1 
115 1 Y 1 L GLU 35  ? OE2 ? B GLU 15  OE2 
116 1 Y 1 L GLU 36  ? CG  ? B GLU 16  CG  
117 1 Y 1 L GLU 36  ? CD  ? B GLU 16  CD  
118 1 Y 1 L GLU 36  ? OE1 ? B GLU 16  OE1 
119 1 Y 1 L GLU 36  ? OE2 ? B GLU 16  OE2 
120 1 Y 1 L HIS 38  ? CG  ? B HIS 18  CG  
121 1 Y 1 L HIS 38  ? ND1 ? B HIS 18  ND1 
122 1 Y 1 L HIS 38  ? CD2 ? B HIS 18  CD2 
123 1 Y 1 L HIS 38  ? CE1 ? B HIS 18  CE1 
124 1 Y 1 L HIS 38  ? NE2 ? B HIS 18  NE2 
125 1 Y 1 L LYS 39  ? CG  ? B LYS 19  CG  
126 1 Y 1 L LYS 39  ? CD  ? B LYS 19  CD  
127 1 Y 1 L LYS 39  ? CE  ? B LYS 19  CE  
128 1 Y 1 L LYS 39  ? NZ  ? B LYS 19  NZ  
129 1 Y 1 L TRP 45  ? CG  ? B TRP 25  CG  
130 1 Y 1 L TRP 45  ? CD1 ? B TRP 25  CD1 
131 1 Y 1 L TRP 45  ? CD2 ? B TRP 25  CD2 
132 1 Y 1 L TRP 45  ? NE1 ? B TRP 25  NE1 
133 1 Y 1 L TRP 45  ? CE2 ? B TRP 25  CE2 
134 1 Y 1 L TRP 45  ? CE3 ? B TRP 25  CE3 
135 1 Y 1 L TRP 45  ? CZ2 ? B TRP 25  CZ2 
136 1 Y 1 L TRP 45  ? CZ3 ? B TRP 25  CZ3 
137 1 Y 1 L TRP 45  ? CH2 ? B TRP 25  CH2 
138 1 Y 1 L PHE 47  ? CG  ? B PHE 27  CG  
139 1 Y 1 L PHE 47  ? CD1 ? B PHE 27  CD1 
140 1 Y 1 L PHE 47  ? CD2 ? B PHE 27  CD2 
141 1 Y 1 L PHE 47  ? CE1 ? B PHE 27  CE1 
142 1 Y 1 L PHE 47  ? CE2 ? B PHE 27  CE2 
143 1 Y 1 L PHE 47  ? CZ  ? B PHE 27  CZ  
144 1 Y 1 L GLU 53  ? CG  ? B GLU 33  CG  
145 1 Y 1 L GLU 53  ? CD  ? B GLU 33  CD  
146 1 Y 1 L GLU 53  ? OE1 ? B GLU 33  OE1 
147 1 Y 1 L GLU 53  ? OE2 ? B GLU 33  OE2 
148 1 Y 1 L SER 54  ? OG  ? B SER 34  OG  
149 1 Y 1 L ASP 57  ? CG  ? B ASP 37  CG  
150 1 Y 1 L ASP 57  ? OD1 ? B ASP 37  OD1 
151 1 Y 1 L ASP 57  ? OD2 ? B ASP 37  OD2 
152 1 Y 1 L PHE 60  ? CG  ? B PHE 40  CG  
153 1 Y 1 L PHE 60  ? CD1 ? B PHE 40  CD1 
154 1 Y 1 L PHE 60  ? CD2 ? B PHE 40  CD2 
155 1 Y 1 L PHE 60  ? CE1 ? B PHE 40  CE1 
156 1 Y 1 L PHE 60  ? CE2 ? B PHE 40  CE2 
157 1 Y 1 L PHE 60  ? CZ  ? B PHE 40  CZ  
158 1 Y 1 L ILE 64  ? CG1 ? B ILE 44  CG1 
159 1 Y 1 L ILE 64  ? CG2 ? B ILE 44  CG2 
160 1 Y 1 L ILE 64  ? CD1 ? B ILE 44  CD1 
161 1 Y 1 L ARG 67  ? CG  ? B ARG 47  CG  
162 1 Y 1 L ARG 67  ? CD  ? B ARG 47  CD  
163 1 Y 1 L ARG 67  ? NE  ? B ARG 47  NE  
164 1 Y 1 L ARG 67  ? CZ  ? B ARG 47  CZ  
165 1 Y 1 L ARG 67  ? NH1 ? B ARG 47  NH1 
166 1 Y 1 L ARG 67  ? NH2 ? B ARG 47  NH2 
167 1 Y 1 L LEU 68  ? CG  ? B LEU 48  CG  
168 1 Y 1 L LEU 68  ? CD1 ? B LEU 48  CD1 
169 1 Y 1 L LEU 68  ? CD2 ? B LEU 48  CD2 
170 1 Y 1 L PHE 70  ? CG  ? B PHE 50  CG  
171 1 Y 1 L PHE 70  ? CD1 ? B PHE 50  CD1 
172 1 Y 1 L PHE 70  ? CD2 ? B PHE 50  CD2 
173 1 Y 1 L PHE 70  ? CE1 ? B PHE 50  CE1 
174 1 Y 1 L PHE 70  ? CE2 ? B PHE 50  CE2 
175 1 Y 1 L PHE 70  ? CZ  ? B PHE 50  CZ  
176 1 Y 1 L LYS 71  ? CG  ? B LYS 51  CG  
177 1 Y 1 L LYS 71  ? CD  ? B LYS 51  CD  
178 1 Y 1 L LYS 71  ? CE  ? B LYS 51  CE  
179 1 Y 1 L LYS 71  ? NZ  ? B LYS 51  NZ  
180 1 Y 1 L GLN 73  ? CG  ? B GLN 53  CG  
181 1 Y 1 L GLN 73  ? CD  ? B GLN 53  CD  
182 1 Y 1 L GLN 73  ? OE1 ? B GLN 53  OE1 
183 1 Y 1 L GLN 73  ? NE2 ? B GLN 53  NE2 
184 1 Y 1 L ARG 78  ? CG  ? B ARG 58  CG  
185 1 Y 1 L ARG 78  ? CD  ? B ARG 58  CD  
186 1 Y 1 L ARG 78  ? NE  ? B ARG 58  NE  
187 1 Y 1 L ARG 78  ? CZ  ? B ARG 58  CZ  
188 1 Y 1 L ARG 78  ? NH1 ? B ARG 58  NH1 
189 1 Y 1 L ARG 78  ? NH2 ? B ARG 58  NH2 
190 1 Y 1 L LYS 79  ? CG  ? B LYS 59  CG  
191 1 Y 1 L LYS 79  ? CD  ? B LYS 59  CD  
192 1 Y 1 L LYS 79  ? CE  ? B LYS 59  CE  
193 1 Y 1 L LYS 79  ? NZ  ? B LYS 59  NZ  
194 1 Y 1 L ARG 80  ? CG  ? B ARG 60  CG  
195 1 Y 1 L ARG 80  ? CD  ? B ARG 60  CD  
196 1 Y 1 L ARG 80  ? NE  ? B ARG 60  NE  
197 1 Y 1 L ARG 80  ? CZ  ? B ARG 60  CZ  
198 1 Y 1 L ARG 80  ? NH1 ? B ARG 60  NH1 
199 1 Y 1 L ARG 80  ? NH2 ? B ARG 60  NH2 
200 1 Y 1 L TRP 82  ? CG  ? B TRP 62  CG  
201 1 Y 1 L TRP 82  ? CD1 ? B TRP 62  CD1 
202 1 Y 1 L TRP 82  ? CD2 ? B TRP 62  CD2 
203 1 Y 1 L TRP 82  ? NE1 ? B TRP 62  NE1 
204 1 Y 1 L TRP 82  ? CE2 ? B TRP 62  CE2 
205 1 Y 1 L TRP 82  ? CE3 ? B TRP 62  CE3 
206 1 Y 1 L TRP 82  ? CZ2 ? B TRP 62  CZ2 
207 1 Y 1 L TRP 82  ? CZ3 ? B TRP 62  CZ3 
208 1 Y 1 L TRP 82  ? CH2 ? B TRP 62  CH2 
209 1 Y 1 L LYS 83  ? CG  ? B LYS 63  CG  
210 1 Y 1 L LYS 83  ? CD  ? B LYS 63  CD  
211 1 Y 1 L LYS 83  ? CE  ? B LYS 63  CE  
212 1 Y 1 L LYS 83  ? NZ  ? B LYS 63  NZ  
213 1 Y 1 L LYS 84  ? CG  ? B LYS 64  CG  
214 1 Y 1 L LYS 84  ? CD  ? B LYS 64  CD  
215 1 Y 1 L LYS 84  ? CE  ? B LYS 64  CE  
216 1 Y 1 L LYS 84  ? NZ  ? B LYS 64  NZ  
217 1 Y 1 L GLU 86  ? CG  ? B GLU 66  CG  
218 1 Y 1 L GLU 86  ? CD  ? B GLU 66  CD  
219 1 Y 1 L GLU 86  ? OE1 ? B GLU 66  OE1 
220 1 Y 1 L GLU 86  ? OE2 ? B GLU 66  OE2 
221 1 Y 1 L LYS 88  ? CG  ? B LYS 68  CG  
222 1 Y 1 L LYS 88  ? CD  ? B LYS 68  CD  
223 1 Y 1 L LYS 88  ? CE  ? B LYS 68  CE  
224 1 Y 1 L LYS 88  ? NZ  ? B LYS 68  NZ  
225 1 Y 1 L ARG 90  ? CG  ? B ARG 70  CG  
226 1 Y 1 L ARG 90  ? CD  ? B ARG 70  CD  
227 1 Y 1 L ARG 90  ? NE  ? B ARG 70  NE  
228 1 Y 1 L ARG 90  ? CZ  ? B ARG 70  CZ  
229 1 Y 1 L ARG 90  ? NH1 ? B ARG 70  NH1 
230 1 Y 1 L ARG 90  ? NH2 ? B ARG 70  NH2 
231 1 Y 1 L LYS 97  ? CG  ? B LYS 77  CG  
232 1 Y 1 L LYS 97  ? CD  ? B LYS 77  CD  
233 1 Y 1 L LYS 97  ? CE  ? B LYS 77  CE  
234 1 Y 1 L LYS 97  ? NZ  ? B LYS 77  NZ  
235 1 Y 1 L LEU 99  ? CG  ? B LEU 79  CG  
236 1 Y 1 L LEU 99  ? CD1 ? B LEU 79  CD1 
237 1 Y 1 L LEU 99  ? CD2 ? B LEU 79  CD2 
238 1 Y 1 L LYS 109 ? CG  ? B LYS 89  CG  
239 1 Y 1 L LYS 109 ? CD  ? B LYS 89  CD  
240 1 Y 1 L LYS 109 ? CE  ? B LYS 89  CE  
241 1 Y 1 L LYS 109 ? NZ  ? B LYS 89  NZ  
242 1 Y 1 L VAL 110 ? CG1 ? B VAL 90  CG1 
243 1 Y 1 L VAL 110 ? CG2 ? B VAL 90  CG2 
244 1 Y 1 L LEU 111 ? CG  ? B LEU 91  CG  
245 1 Y 1 L LEU 111 ? CD1 ? B LEU 91  CD1 
246 1 Y 1 L LEU 111 ? CD2 ? B LEU 91  CD2 
247 1 Y 1 L GLN 139 ? CG  ? B GLN 119 CG  
248 1 Y 1 L GLN 139 ? CD  ? B GLN 119 CD  
249 1 Y 1 L GLN 139 ? OE1 ? B GLN 119 OE1 
250 1 Y 1 L GLN 139 ? NE2 ? B GLN 119 NE2 
251 1 Y 1 L ARG 140 ? CG  ? B ARG 120 CG  
252 1 Y 1 L ARG 140 ? CD  ? B ARG 120 CD  
253 1 Y 1 L ARG 140 ? NE  ? B ARG 120 NE  
254 1 Y 1 L ARG 140 ? CZ  ? B ARG 120 CZ  
255 1 Y 1 L ARG 140 ? NH1 ? B ARG 120 NH1 
256 1 Y 1 L ARG 140 ? NH2 ? B ARG 120 NH2 
257 1 Y 1 L HIS 146 ? CG  ? B HIS 126 CG  
258 1 Y 1 L HIS 146 ? ND1 ? B HIS 126 ND1 
259 1 Y 1 L HIS 146 ? CD2 ? B HIS 126 CD2 
260 1 Y 1 L HIS 146 ? CE1 ? B HIS 126 CE1 
261 1 Y 1 L HIS 146 ? NE2 ? B HIS 126 NE2 
262 1 Y 1 A GLU 8   ? CG  ? C GLU 8   CG  
263 1 Y 1 A GLU 8   ? CD  ? C GLU 8   CD  
264 1 Y 1 A GLU 8   ? OE1 ? C GLU 8   OE1 
265 1 Y 1 A GLU 8   ? OE2 ? C GLU 8   OE2 
266 1 Y 1 A LYS 10  ? CG  ? C LYS 10  CG  
267 1 Y 1 A LYS 10  ? CD  ? C LYS 10  CD  
268 1 Y 1 A LYS 10  ? CE  ? C LYS 10  CE  
269 1 Y 1 A LYS 10  ? NZ  ? C LYS 10  NZ  
270 1 Y 1 A GLU 14  ? CG  ? C GLU 14  CG  
271 1 Y 1 A GLU 14  ? CD  ? C GLU 14  CD  
272 1 Y 1 A GLU 14  ? OE1 ? C GLU 14  OE1 
273 1 Y 1 A GLU 14  ? OE2 ? C GLU 14  OE2 
274 1 Y 1 A MET 18  ? CG  ? C MET 18  CG  
275 1 Y 1 A MET 18  ? SD  ? C MET 18  SD  
276 1 Y 1 A MET 18  ? CE  ? C MET 18  CE  
277 1 Y 1 A GLU 25  ? CG  ? C GLU 25  CG  
278 1 Y 1 A GLU 25  ? CD  ? C GLU 25  CD  
279 1 Y 1 A GLU 25  ? OE1 ? C GLU 25  OE1 
280 1 Y 1 A GLU 25  ? OE2 ? C GLU 25  OE2 
281 1 Y 1 A ASP 26  ? CG  ? C ASP 26  CG  
282 1 Y 1 A ASP 26  ? OD1 ? C ASP 26  OD1 
283 1 Y 1 A ASP 26  ? OD2 ? C ASP 26  OD2 
284 1 Y 1 A GLU 28  ? CG  ? C GLU 28  CG  
285 1 Y 1 A GLU 28  ? CD  ? C GLU 28  CD  
286 1 Y 1 A GLU 28  ? OE1 ? C GLU 28  OE1 
287 1 Y 1 A GLU 28  ? OE2 ? C GLU 28  OE2 
288 1 Y 1 A LYS 29  ? CG  ? C LYS 29  CG  
289 1 Y 1 A LYS 29  ? CD  ? C LYS 29  CD  
290 1 Y 1 A LYS 29  ? CE  ? C LYS 29  CE  
291 1 Y 1 A LYS 29  ? NZ  ? C LYS 29  NZ  
292 1 Y 1 A GLU 33  ? CG  ? C GLU 33  CG  
293 1 Y 1 A GLU 33  ? CD  ? C GLU 33  CD  
294 1 Y 1 A GLU 33  ? OE1 ? C GLU 33  OE1 
295 1 Y 1 A GLU 33  ? OE2 ? C GLU 33  OE2 
296 1 Y 1 A LYS 35  ? CG  ? C LYS 35  CG  
297 1 Y 1 A LYS 35  ? CD  ? C LYS 35  CD  
298 1 Y 1 A LYS 35  ? CE  ? C LYS 35  CE  
299 1 Y 1 A LYS 35  ? NZ  ? C LYS 35  NZ  
300 1 Y 1 A GLU 43  ? CG  ? C GLU 43  CG  
301 1 Y 1 A GLU 43  ? CD  ? C GLU 43  CD  
302 1 Y 1 A GLU 43  ? OE1 ? C GLU 43  OE1 
303 1 Y 1 A GLU 43  ? OE2 ? C GLU 43  OE2 
304 1 Y 1 A LYS 46  ? CG  ? C LYS 46  CG  
305 1 Y 1 A LYS 46  ? CD  ? C LYS 46  CD  
306 1 Y 1 A LYS 46  ? CE  ? C LYS 46  CE  
307 1 Y 1 A LYS 46  ? NZ  ? C LYS 46  NZ  
308 1 Y 1 A ILE 49  ? CG1 ? C ILE 49  CG1 
309 1 Y 1 A ILE 49  ? CG2 ? C ILE 49  CG2 
310 1 Y 1 A ILE 49  ? CD1 ? C ILE 49  CD1 
311 1 Y 1 A ARG 205 ? CG  ? C ARG 205 CG  
312 1 Y 1 A ARG 205 ? CD  ? C ARG 205 CD  
313 1 Y 1 A ARG 205 ? NE  ? C ARG 205 NE  
314 1 Y 1 A ARG 205 ? CZ  ? C ARG 205 CZ  
315 1 Y 1 A ARG 205 ? NH1 ? C ARG 205 NH1 
316 1 Y 1 A ARG 205 ? NH2 ? C ARG 205 NH2 
317 1 Y 1 A GLU 207 ? CG  ? C GLU 207 CG  
318 1 Y 1 A GLU 207 ? CD  ? C GLU 207 CD  
319 1 Y 1 A GLU 207 ? OE1 ? C GLU 207 OE1 
320 1 Y 1 A GLU 207 ? OE2 ? C GLU 207 OE2 
321 1 Y 1 A ASP 229 ? CG  ? C ASP 229 CG  
322 1 Y 1 A ASP 229 ? OD1 ? C ASP 229 OD1 
323 1 Y 1 A ASP 229 ? OD2 ? C ASP 229 OD2 
324 1 Y 1 A LEU 234 ? CG  ? C LEU 234 CG  
325 1 Y 1 A LEU 234 ? CD1 ? C LEU 234 CD1 
326 1 Y 1 A LEU 234 ? CD2 ? C LEU 234 CD2 
327 1 Y 1 A ARG 242 ? CG  ? C ARG 242 CG  
328 1 Y 1 A ARG 242 ? CD  ? C ARG 242 CD  
329 1 Y 1 A ARG 242 ? NE  ? C ARG 242 NE  
330 1 Y 1 A ARG 242 ? CZ  ? C ARG 242 CZ  
331 1 Y 1 A ARG 242 ? NH1 ? C ARG 242 NH1 
332 1 Y 1 A ARG 242 ? NH2 ? C ARG 242 NH2 
333 1 Y 1 A LYS 248 ? CG  ? C LYS 248 CG  
334 1 Y 1 A LYS 248 ? CD  ? C LYS 248 CD  
335 1 Y 1 A LYS 248 ? CE  ? C LYS 248 CE  
336 1 Y 1 A LYS 248 ? NZ  ? C LYS 248 NZ  
337 1 Y 1 A LYS 270 ? CG  ? C LYS 270 CG  
338 1 Y 1 A LYS 270 ? CD  ? C LYS 270 CD  
339 1 Y 1 A LYS 270 ? CE  ? C LYS 270 CE  
340 1 Y 1 A LYS 270 ? NZ  ? C LYS 270 NZ  
341 1 Y 1 A ASP 272 ? CG  ? C ASP 272 CG  
342 1 Y 1 A ASP 272 ? OD1 ? C ASP 272 OD1 
343 1 Y 1 A ASP 272 ? OD2 ? C ASP 272 OD2 
344 1 Y 1 A GLU 275 ? CG  ? C GLU 275 CG  
345 1 Y 1 A GLU 275 ? CD  ? C GLU 275 CD  
346 1 Y 1 A GLU 275 ? OE1 ? C GLU 275 OE1 
347 1 Y 1 A GLU 275 ? OE2 ? C GLU 275 OE2 
348 1 Y 1 A GLU 276 ? CG  ? C GLU 276 CG  
349 1 Y 1 A GLU 276 ? CD  ? C GLU 276 CD  
350 1 Y 1 A GLU 276 ? OE1 ? C GLU 276 OE1 
351 1 Y 1 A GLU 276 ? OE2 ? C GLU 276 OE2 
352 1 Y 1 A LYS 279 ? CG  ? C LYS 279 CG  
353 1 Y 1 A LYS 279 ? CD  ? C LYS 279 CD  
354 1 Y 1 A LYS 279 ? CE  ? C LYS 279 CE  
355 1 Y 1 A LYS 279 ? NZ  ? C LYS 279 NZ  
356 1 Y 1 A LYS 280 ? CG  ? C LYS 280 CG  
357 1 Y 1 A LYS 280 ? CD  ? C LYS 280 CD  
358 1 Y 1 A LYS 280 ? CE  ? C LYS 280 CE  
359 1 Y 1 A LYS 280 ? NZ  ? C LYS 280 NZ  
360 1 Y 1 A GLU 297 ? CG  ? C GLU 297 CG  
361 1 Y 1 A GLU 297 ? CD  ? C GLU 297 CD  
362 1 Y 1 A GLU 297 ? OE1 ? C GLU 297 OE1 
363 1 Y 1 A GLU 297 ? OE2 ? C GLU 297 OE2 
364 1 Y 1 A LYS 312 ? CG  ? C LYS 312 CG  
365 1 Y 1 A LYS 312 ? CD  ? C LYS 312 CD  
366 1 Y 1 A LYS 312 ? CE  ? C LYS 312 CE  
367 1 Y 1 A LYS 312 ? NZ  ? C LYS 312 NZ  
368 1 Y 1 A ASP 315 ? CG  ? C ASP 315 CG  
369 1 Y 1 A ASP 315 ? OD1 ? C ASP 315 OD1 
370 1 Y 1 A ASP 315 ? OD2 ? C ASP 315 OD2 
371 1 Y 1 A LYS 345 ? CG  ? C LYS 345 CG  
372 1 Y 1 A LYS 345 ? CD  ? C LYS 345 CD  
373 1 Y 1 A LYS 345 ? CE  ? C LYS 345 CE  
374 1 Y 1 A LYS 345 ? NZ  ? C LYS 345 NZ  
375 1 Y 1 A ASN 346 ? CG  ? C ASN 346 CG  
376 1 Y 1 A ASN 346 ? OD1 ? C ASN 346 OD1 
377 1 Y 1 A ASN 346 ? ND2 ? C ASN 346 ND2 
378 1 Y 1 A LYS 349 ? CG  ? C LYS 349 CG  
379 1 Y 1 A LYS 349 ? CD  ? C LYS 349 CD  
380 1 Y 1 A LYS 349 ? CE  ? C LYS 349 CE  
381 1 Y 1 A LYS 349 ? NZ  ? C LYS 349 NZ  
382 1 Y 1 B LEU 7   ? CG  ? D LEU 7   CG  
383 1 Y 1 B LEU 7   ? CD1 ? D LEU 7   CD1 
384 1 Y 1 B LEU 7   ? CD2 ? D LEU 7   CD2 
385 1 Y 1 B ARG 8   ? CG  ? D ARG 8   CG  
386 1 Y 1 B ARG 8   ? CD  ? D ARG 8   CD  
387 1 Y 1 B ARG 8   ? NE  ? D ARG 8   NE  
388 1 Y 1 B ARG 8   ? CZ  ? D ARG 8   CZ  
389 1 Y 1 B ARG 8   ? NH1 ? D ARG 8   NH1 
390 1 Y 1 B ARG 8   ? NH2 ? D ARG 8   NH2 
391 1 Y 1 B GLN 9   ? CG  ? D GLN 9   CG  
392 1 Y 1 B GLN 9   ? CD  ? D GLN 9   CD  
393 1 Y 1 B GLN 9   ? OE1 ? D GLN 9   OE1 
394 1 Y 1 B GLN 9   ? NE2 ? D GLN 9   NE2 
395 1 Y 1 B GLU 10  ? CG  ? D GLU 10  CG  
396 1 Y 1 B GLU 10  ? CD  ? D GLU 10  CD  
397 1 Y 1 B GLU 10  ? OE1 ? D GLU 10  OE1 
398 1 Y 1 B GLU 10  ? OE2 ? D GLU 10  OE2 
399 1 Y 1 B GLU 12  ? CG  ? D GLU 12  CG  
400 1 Y 1 B GLU 12  ? CD  ? D GLU 12  CD  
401 1 Y 1 B GLU 12  ? OE1 ? D GLU 12  OE1 
402 1 Y 1 B GLU 12  ? OE2 ? D GLU 12  OE2 
403 1 Y 1 B GLN 13  ? CG  ? D GLN 13  CG  
404 1 Y 1 B GLN 13  ? CD  ? D GLN 13  CD  
405 1 Y 1 B GLN 13  ? OE1 ? D GLN 13  OE1 
406 1 Y 1 B GLN 13  ? NE2 ? D GLN 13  NE2 
407 1 Y 1 B LYS 15  ? CG  ? D LYS 15  CG  
408 1 Y 1 B LYS 15  ? CD  ? D LYS 15  CD  
409 1 Y 1 B LYS 15  ? CE  ? D LYS 15  CE  
410 1 Y 1 B LYS 15  ? NZ  ? D LYS 15  NZ  
411 1 Y 1 B ASN 16  ? CG  ? D ASN 16  CG  
412 1 Y 1 B ASN 16  ? OD1 ? D ASN 16  OD1 
413 1 Y 1 B ASN 16  ? ND2 ? D ASN 16  ND2 
414 1 Y 1 B GLN 17  ? CG  ? D GLN 17  CG  
415 1 Y 1 B GLN 17  ? CD  ? D GLN 17  CD  
416 1 Y 1 B GLN 17  ? OE1 ? D GLN 17  OE1 
417 1 Y 1 B GLN 17  ? NE2 ? D GLN 17  NE2 
418 1 Y 1 B ILE 18  ? CG1 ? D ILE 18  CG1 
419 1 Y 1 B ILE 18  ? CG2 ? D ILE 18  CG2 
420 1 Y 1 B ILE 18  ? CD1 ? D ILE 18  CD1 
421 1 Y 1 B ARG 19  ? CG  ? D ARG 19  CG  
422 1 Y 1 B ARG 19  ? CD  ? D ARG 19  CD  
423 1 Y 1 B ARG 19  ? NE  ? D ARG 19  NE  
424 1 Y 1 B ARG 19  ? CZ  ? D ARG 19  CZ  
425 1 Y 1 B ARG 19  ? NH1 ? D ARG 19  NH1 
426 1 Y 1 B ARG 19  ? NH2 ? D ARG 19  NH2 
427 1 Y 1 B ASP 20  ? CG  ? D ASP 20  CG  
428 1 Y 1 B ASP 20  ? OD1 ? D ASP 20  OD1 
429 1 Y 1 B ASP 20  ? OD2 ? D ASP 20  OD2 
430 1 Y 1 B LYS 23  ? CG  ? D LYS 23  CG  
431 1 Y 1 B LYS 23  ? CD  ? D LYS 23  CD  
432 1 Y 1 B LYS 23  ? CE  ? D LYS 23  CE  
433 1 Y 1 B LYS 23  ? NZ  ? D LYS 23  NZ  
434 1 Y 1 B ASP 27  ? CG  ? D ASP 27  CG  
435 1 Y 1 B ASP 27  ? OD1 ? D ASP 27  OD1 
436 1 Y 1 B ASP 27  ? OD2 ? D ASP 27  OD2 
437 1 Y 1 B THR 29  ? OG1 ? D THR 29  OG1 
438 1 Y 1 B THR 29  ? CG2 ? D THR 29  CG2 
439 1 Y 1 B GLN 32  ? CG  ? D GLN 32  CG  
440 1 Y 1 B GLN 32  ? CD  ? D GLN 32  CD  
441 1 Y 1 B GLN 32  ? OE1 ? D GLN 32  OE1 
442 1 Y 1 B GLN 32  ? NE2 ? D GLN 32  NE2 
443 1 Y 1 B ASN 35  ? CG  ? D ASN 35  CG  
444 1 Y 1 B ASN 35  ? OD1 ? D ASN 35  OD1 
445 1 Y 1 B ASN 35  ? ND2 ? D ASN 35  ND2 
446 1 Y 1 B ASN 36  ? CG  ? D ASN 36  CG  
447 1 Y 1 B ASN 36  ? OD1 ? D ASN 36  OD1 
448 1 Y 1 B ASN 36  ? ND2 ? D ASN 36  ND2 
449 1 Y 1 B ASP 38  ? CG  ? D ASP 38  CG  
450 1 Y 1 B ASP 38  ? OD1 ? D ASP 38  OD1 
451 1 Y 1 B ASP 38  ? OD2 ? D ASP 38  OD2 
452 1 Y 1 B ARG 42  ? CG  ? D ARG 42  CG  
453 1 Y 1 B ARG 42  ? CD  ? D ARG 42  CD  
454 1 Y 1 B ARG 42  ? NE  ? D ARG 42  NE  
455 1 Y 1 B ARG 42  ? CZ  ? D ARG 42  CZ  
456 1 Y 1 B ARG 42  ? NH1 ? D ARG 42  NH1 
457 1 Y 1 B ARG 42  ? NH2 ? D ARG 42  NH2 
458 1 Y 1 B GLN 44  ? CG  ? D GLN 44  CG  
459 1 Y 1 B GLN 44  ? CD  ? D GLN 44  CD  
460 1 Y 1 B GLN 44  ? OE1 ? D GLN 44  OE1 
461 1 Y 1 B GLN 44  ? NE2 ? D GLN 44  NE2 
462 1 Y 1 B ARG 46  ? CG  ? D ARG 46  CG  
463 1 Y 1 B ARG 46  ? CD  ? D ARG 46  CD  
464 1 Y 1 B ARG 46  ? NE  ? D ARG 46  NE  
465 1 Y 1 B ARG 46  ? CZ  ? D ARG 46  CZ  
466 1 Y 1 B ARG 46  ? NH1 ? D ARG 46  NH1 
467 1 Y 1 B ARG 46  ? NH2 ? D ARG 46  NH2 
468 1 Y 1 B ARG 96  ? CG  ? D ARG 96  CG  
469 1 Y 1 B ARG 96  ? CD  ? D ARG 96  CD  
470 1 Y 1 B ARG 96  ? NE  ? D ARG 96  NE  
471 1 Y 1 B ARG 96  ? CZ  ? D ARG 96  CZ  
472 1 Y 1 B ARG 96  ? NH1 ? D ARG 96  NH1 
473 1 Y 1 B ARG 96  ? NH2 ? D ARG 96  NH2 
474 1 Y 1 B ASP 154 ? CG  ? D ASP 154 CG  
475 1 Y 1 B ASP 154 ? OD1 ? D ASP 154 OD1 
476 1 Y 1 B ASP 154 ? OD2 ? D ASP 154 OD2 
477 1 Y 1 B GLU 172 ? CG  ? D GLU 172 CG  
478 1 Y 1 B GLU 172 ? CD  ? D GLU 172 CD  
479 1 Y 1 B GLU 172 ? OE1 ? D GLU 172 OE1 
480 1 Y 1 B GLU 172 ? OE2 ? D GLU 172 OE2 
481 1 Y 1 B ARG 197 ? CG  ? D ARG 197 CG  
482 1 Y 1 B ARG 197 ? CD  ? D ARG 197 CD  
483 1 Y 1 B ARG 197 ? NE  ? D ARG 197 NE  
484 1 Y 1 B ARG 197 ? CZ  ? D ARG 197 CZ  
485 1 Y 1 B ARG 197 ? NH1 ? D ARG 197 NH1 
486 1 Y 1 B ARG 197 ? NH2 ? D ARG 197 NH2 
487 1 Y 1 B ARG 214 ? CG  ? D ARG 214 CG  
488 1 Y 1 B ARG 214 ? CD  ? D ARG 214 CD  
489 1 Y 1 B ARG 214 ? NE  ? D ARG 214 NE  
490 1 Y 1 B ARG 214 ? CZ  ? D ARG 214 CZ  
491 1 Y 1 B ARG 214 ? NH1 ? D ARG 214 NH1 
492 1 Y 1 B ARG 214 ? NH2 ? D ARG 214 NH2 
493 1 Y 1 B GLU 215 ? CG  ? D GLU 215 CG  
494 1 Y 1 B GLU 215 ? CD  ? D GLU 215 CD  
495 1 Y 1 B GLU 215 ? OE1 ? D GLU 215 OE1 
496 1 Y 1 B GLU 215 ? OE2 ? D GLU 215 OE2 
497 1 Y 1 B MET 217 ? CG  ? D MET 217 CG  
498 1 Y 1 B MET 217 ? SD  ? D MET 217 SD  
499 1 Y 1 B MET 217 ? CE  ? D MET 217 CE  
500 1 Y 1 B ARG 256 ? CG  ? D ARG 256 CG  
501 1 Y 1 B ARG 256 ? CD  ? D ARG 256 CD  
502 1 Y 1 B ARG 256 ? NE  ? D ARG 256 NE  
503 1 Y 1 B ARG 256 ? CZ  ? D ARG 256 CZ  
504 1 Y 1 B ARG 256 ? NH1 ? D ARG 256 NH1 
505 1 Y 1 B ARG 256 ? NH2 ? D ARG 256 NH2 
506 1 Y 1 B ASP 323 ? CG  ? D ASP 323 CG  
507 1 Y 1 B ASP 323 ? OD1 ? D ASP 323 OD1 
508 1 Y 1 B ASP 323 ? OD2 ? D ASP 323 OD2 
509 1 Y 1 C ARG 13  ? CG  ? E ARG 13  CG  
510 1 Y 1 C ARG 13  ? CD  ? E ARG 13  CD  
511 1 Y 1 C ARG 13  ? NE  ? E ARG 13  NE  
512 1 Y 1 C ARG 13  ? CZ  ? E ARG 13  CZ  
513 1 Y 1 C ARG 13  ? NH1 ? E ARG 13  NH1 
514 1 Y 1 C ARG 13  ? NH2 ? E ARG 13  NH2 
515 1 Y 1 C LYS 14  ? CG  ? E LYS 14  CG  
516 1 Y 1 C LYS 14  ? CD  ? E LYS 14  CD  
517 1 Y 1 C LYS 14  ? CE  ? E LYS 14  CE  
518 1 Y 1 C LYS 14  ? NZ  ? E LYS 14  NZ  
519 1 Y 1 C LEU 15  ? CG  ? E LEU 15  CG  
520 1 Y 1 C LEU 15  ? CD1 ? E LEU 15  CD1 
521 1 Y 1 C LEU 15  ? CD2 ? E LEU 15  CD2 
522 1 Y 1 C GLU 17  ? CG  ? E GLU 17  CG  
523 1 Y 1 C GLU 17  ? CD  ? E GLU 17  CD  
524 1 Y 1 C GLU 17  ? OE1 ? E GLU 17  OE1 
525 1 Y 1 C GLU 17  ? OE2 ? E GLU 17  OE2 
526 1 Y 1 C LEU 19  ? CG  ? E LEU 19  CG  
527 1 Y 1 C LEU 19  ? CD1 ? E LEU 19  CD1 
528 1 Y 1 C LEU 19  ? CD2 ? E LEU 19  CD2 
529 1 Y 1 C LYS 20  ? CG  ? E LYS 20  CG  
530 1 Y 1 C LYS 20  ? CD  ? E LYS 20  CD  
531 1 Y 1 C LYS 20  ? CE  ? E LYS 20  CE  
532 1 Y 1 C LYS 20  ? NZ  ? E LYS 20  NZ  
533 1 Y 1 C MET 21  ? CG  ? E MET 21  CG  
534 1 Y 1 C MET 21  ? SD  ? E MET 21  SD  
535 1 Y 1 C MET 21  ? CE  ? E MET 21  CE  
536 1 Y 1 C GLU 22  ? CG  ? E GLU 22  CG  
537 1 Y 1 C GLU 22  ? CD  ? E GLU 22  CD  
538 1 Y 1 C GLU 22  ? OE1 ? E GLU 22  OE1 
539 1 Y 1 C GLU 22  ? OE2 ? E GLU 22  OE2 
540 1 Y 1 C ASN 24  ? CG  ? E ASN 24  CG  
541 1 Y 1 C ASN 24  ? OD1 ? E ASN 24  OD1 
542 1 Y 1 C ASN 24  ? ND2 ? E ASN 24  ND2 
543 1 Y 1 C ILE 25  ? CG1 ? E ILE 25  CG1 
544 1 Y 1 C ILE 25  ? CG2 ? E ILE 25  CG2 
545 1 Y 1 C ILE 25  ? CD1 ? E ILE 25  CD1 
546 1 Y 1 C ASP 26  ? CG  ? E ASP 26  CG  
547 1 Y 1 C ASP 26  ? OD1 ? E ASP 26  OD1 
548 1 Y 1 C ASP 26  ? OD2 ? E ASP 26  OD2 
549 1 Y 1 C LYS 29  ? CG  ? E LYS 29  CG  
550 1 Y 1 C LYS 29  ? CD  ? E LYS 29  CD  
551 1 Y 1 C LYS 29  ? CE  ? E LYS 29  CE  
552 1 Y 1 C LYS 29  ? NZ  ? E LYS 29  NZ  
553 1 Y 1 C LYS 32  ? CG  ? E LYS 32  CG  
554 1 Y 1 C LYS 32  ? CD  ? E LYS 32  CD  
555 1 Y 1 C LYS 32  ? CE  ? E LYS 32  CE  
556 1 Y 1 C LYS 32  ? NZ  ? E LYS 32  NZ  
557 1 Y 1 C ASP 36  ? CG  ? E ASP 36  CG  
558 1 Y 1 C ASP 36  ? OD1 ? E ASP 36  OD1 
559 1 Y 1 C ASP 36  ? OD2 ? E ASP 36  OD2 
560 1 Y 1 C LYS 46  ? CG  ? E LYS 46  CG  
561 1 Y 1 C LYS 46  ? CD  ? E LYS 46  CD  
562 1 Y 1 C LYS 46  ? CE  ? E LYS 46  CE  
563 1 Y 1 C LYS 46  ? NZ  ? E LYS 46  NZ  
564 1 Y 1 C GLU 47  ? CG  ? E GLU 47  CG  
565 1 Y 1 C GLU 47  ? CD  ? E GLU 47  CD  
566 1 Y 1 C GLU 47  ? OE1 ? E GLU 47  OE1 
567 1 Y 1 C GLU 47  ? OE2 ? E GLU 47  OE2 
568 1 Y 1 C ASP 48  ? CG  ? E ASP 48  CG  
569 1 Y 1 C ASP 48  ? OD1 ? E ASP 48  OD1 
570 1 Y 1 C ASP 48  ? OD2 ? E ASP 48  OD2 
571 1 Y 1 C ARG 62  ? CG  ? E ARG 62  CG  
572 1 Y 1 C ARG 62  ? CD  ? E ARG 62  CD  
573 1 Y 1 C ARG 62  ? NE  ? E ARG 62  NE  
574 1 Y 1 C ARG 62  ? CZ  ? E ARG 62  CZ  
575 1 Y 1 C ARG 62  ? NH1 ? E ARG 62  NH1 
576 1 Y 1 C ARG 62  ? NH2 ? E ARG 62  NH2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9L3Y 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9L3Y 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9L3Y 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9L3Y 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            3.6 
_refine.ls_d_res_low                             ? 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'REAL-SPACE (WEIGHTED MAP SUM AT ATOM CENTERS)' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.002 ? 7551  ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.539 ? 10297 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 3.803 ? 1038  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.039 ? 1226  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.004 ? 1285  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9L3Y 
_struct.title                        
'Cryo-EM structure of the G-protein coupled receptor 1 (GPR1) in complex with chemerin and Gi1' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9L3Y 
_struct_keywords.text            'GPCR, GPR1, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP CML2_HUMAN  P46091 ? 1 
;MEDLEETLFEEFENYSYDLDYYSLESDLEEKVQLGVVHWVSLVLYCLAFVLGIPGNAIVIWFTGFKWKKTVTTLWFLNLA
IADFIFLLFLPLYISYVAMNFHWPFGIWLCKANSFTAQLNMFASVFFLTVISLDHYIHLIHPVLSHRHRTLKNSLIVIIF
IWLLASLIGGPALYFRDTVEFNNHTLCYNNFQKHDPDLTLIRHHVLTWVKFIIGYLFPLLTMSICYLCLIFKVKKRSILI
SSRHFWTILVVVVAFVVCWTPYHLFSIWELTIHHNSYSHHVMQAGIPLSTGLAFLNSCLNPILYVLISKKFQARFRSSVA
EI
;
1  
2 UNP RARR2_HUMAN Q99969 ? 2 
;ELTEAQRRGLQVALEEFHKHPPVQWAFQETSVESAVDTPFPAGIFVRLEFKLQQTSCRKRDWKKPECKVRPNGRKRKCLA
CIKLGSEDKVLGRLVHCPIETQVLREAEEHQETQCLRVQRAGEDPHSFYFPGQFAFS
;
21 
3 UNP GNAI1_HUMAN P63096 ? 3 
;MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQS
IIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLD
RIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM
NRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIY
THFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF
;
1  
4 UNP GBB1_HUMAN  P62873 ? 4 
;MSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLI
IWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTS
SGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNA
FATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGV
TDDGMAVATGSWDSFLKIWN
;
1  
5 UNP GBG2_HUMAN  P59768 ? 5 MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL 1  
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9L3Y R 1 ? 322 ? P46091 1  ? 322 ? 1  322 
2 2 9L3Y L 1 ? 137 ? Q99969 21 ? 157 ? 21 157 
3 3 9L3Y A 1 ? 354 ? P63096 1  ? 354 ? 1  354 
4 4 9L3Y B 1 ? 340 ? P62873 1  ? 340 ? 1  340 
5 5 9L3Y C 1 ? 71  ? P59768 1  ? 71  ? 1  71  
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9L3Y GLU R 323 ? UNP P46091 ?   ?   'expression tag'      323 1  
1 9L3Y PHE R 324 ? UNP P46091 ?   ?   'expression tag'      324 2  
1 9L3Y LEU R 325 ? UNP P46091 ?   ?   'expression tag'      325 3  
1 9L3Y GLU R 326 ? UNP P46091 ?   ?   'expression tag'      326 4  
1 9L3Y VAL R 327 ? UNP P46091 ?   ?   'expression tag'      327 5  
1 9L3Y LEU R 328 ? UNP P46091 ?   ?   'expression tag'      328 6  
1 9L3Y PHE R 329 ? UNP P46091 ?   ?   'expression tag'      329 7  
1 9L3Y GLN R 330 ? UNP P46091 ?   ?   'expression tag'      330 8  
1 9L3Y GLY R 331 ? UNP P46091 ?   ?   'expression tag'      331 9  
1 9L3Y PRO R 332 ? UNP P46091 ?   ?   'expression tag'      332 10 
1 9L3Y TRP R 333 ? UNP P46091 ?   ?   'expression tag'      333 11 
1 9L3Y SER R 334 ? UNP P46091 ?   ?   'expression tag'      334 12 
1 9L3Y HIS R 335 ? UNP P46091 ?   ?   'expression tag'      335 13 
1 9L3Y PRO R 336 ? UNP P46091 ?   ?   'expression tag'      336 14 
1 9L3Y GLN R 337 ? UNP P46091 ?   ?   'expression tag'      337 15 
1 9L3Y PHE R 338 ? UNP P46091 ?   ?   'expression tag'      338 16 
1 9L3Y GLU R 339 ? UNP P46091 ?   ?   'expression tag'      339 17 
1 9L3Y LYS R 340 ? UNP P46091 ?   ?   'expression tag'      340 18 
1 9L3Y GLY R 341 ? UNP P46091 ?   ?   'expression tag'      341 19 
1 9L3Y GLY R 342 ? UNP P46091 ?   ?   'expression tag'      342 20 
1 9L3Y GLY R 343 ? UNP P46091 ?   ?   'expression tag'      343 21 
1 9L3Y SER R 344 ? UNP P46091 ?   ?   'expression tag'      344 22 
1 9L3Y GLY R 345 ? UNP P46091 ?   ?   'expression tag'      345 23 
1 9L3Y GLY R 346 ? UNP P46091 ?   ?   'expression tag'      346 24 
1 9L3Y GLY R 347 ? UNP P46091 ?   ?   'expression tag'      347 25 
1 9L3Y SER R 348 ? UNP P46091 ?   ?   'expression tag'      348 26 
1 9L3Y GLY R 349 ? UNP P46091 ?   ?   'expression tag'      349 27 
1 9L3Y GLY R 350 ? UNP P46091 ?   ?   'expression tag'      350 28 
1 9L3Y SER R 351 ? UNP P46091 ?   ?   'expression tag'      351 29 
1 9L3Y ALA R 352 ? UNP P46091 ?   ?   'expression tag'      352 30 
1 9L3Y TRP R 353 ? UNP P46091 ?   ?   'expression tag'      353 31 
1 9L3Y SER R 354 ? UNP P46091 ?   ?   'expression tag'      354 32 
1 9L3Y HIS R 355 ? UNP P46091 ?   ?   'expression tag'      355 33 
1 9L3Y PRO R 356 ? UNP P46091 ?   ?   'expression tag'      356 34 
1 9L3Y GLN R 357 ? UNP P46091 ?   ?   'expression tag'      357 35 
1 9L3Y PHE R 358 ? UNP P46091 ?   ?   'expression tag'      358 36 
1 9L3Y GLU R 359 ? UNP P46091 ?   ?   'expression tag'      359 37 
1 9L3Y LYS R 360 ? UNP P46091 ?   ?   'expression tag'      360 38 
1 9L3Y ASP R 361 ? UNP P46091 ?   ?   'expression tag'      361 39 
1 9L3Y TYR R 362 ? UNP P46091 ?   ?   'expression tag'      362 40 
1 9L3Y LYS R 363 ? UNP P46091 ?   ?   'expression tag'      363 41 
1 9L3Y ASP R 364 ? UNP P46091 ?   ?   'expression tag'      364 42 
1 9L3Y ASP R 365 ? UNP P46091 ?   ?   'expression tag'      365 43 
1 9L3Y ASP R 366 ? UNP P46091 ?   ?   'expression tag'      366 44 
1 9L3Y ASP R 367 ? UNP P46091 ?   ?   'expression tag'      367 45 
1 9L3Y LYS R 368 ? UNP P46091 ?   ?   'expression tag'      368 46 
3 9L3Y CYS A 47  ? UNP P63096 SER 47  'engineered mutation' 47  47 
3 9L3Y THR A 202 ? UNP P63096 GLY 202 'engineered mutation' 202 48 
3 9L3Y ALA A 203 ? UNP P63096 GLY 203 'engineered mutation' 203 49 
3 9L3Y ALA A 245 ? UNP P63096 GLU 245 'engineered mutation' 245 50 
3 9L3Y SER A 326 ? UNP P63096 ALA 326 'engineered mutation' 326 51 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   pentameric 
_pdbx_struct_assembly.oligomeric_count     5 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 VAL A 36  ? GLY A 52  ? VAL R 36  GLY R 52  1 ? 17 
HELX_P HELX_P2  AA2 GLY A 52  ? THR A 63  ? GLY R 52  THR R 63  1 ? 12 
HELX_P HELX_P3  AA3 THR A 70  ? MET A 99  ? THR R 70  MET R 99  1 ? 30 
HELX_P HELX_P4  AA4 GLY A 106 ? HIS A 141 ? GLY R 106 HIS R 141 1 ? 36 
HELX_P HELX_P5  AA5 THR A 150 ? LEU A 167 ? THR R 150 LEU R 167 1 ? 18 
HELX_P HELX_P6  AA6 ARG A 202 ? TYR A 215 ? ARG R 202 TYR R 215 1 ? 14 
HELX_P HELX_P7  AA7 TYR A 215 ? VAL A 233 ? TYR R 215 VAL R 233 1 ? 19 
HELX_P HELX_P8  AA8 LYS A 234 ? ARG A 236 ? LYS R 234 ARG R 236 5 ? 3  
HELX_P HELX_P9  AA9 ILE A 240 ? TRP A 268 ? ILE R 240 TRP R 268 1 ? 29 
HELX_P HELX_P10 AB1 ALA A 284 ? VAL A 305 ? ALA R 284 VAL R 305 1 ? 22 
HELX_P HELX_P11 AB2 GLU B 4   ? HIS B 20  ? GLU L 24  HIS L 40  1 ? 17 
HELX_P HELX_P12 AB3 GLN B 114 ? ARG B 120 ? GLN L 134 ARG L 140 1 ? 7  
HELX_P HELX_P13 AB4 ALA C 7   ? ARG C 32  ? ALA A 7   ARG A 32  1 ? 26 
HELX_P HELX_P14 AB5 ARG C 208 ? HIS C 213 ? ARG A 208 HIS A 213 1 ? 6  
HELX_P HELX_P15 AB6 CYS C 214 ? GLU C 216 ? CYS A 214 GLU A 216 5 ? 3  
HELX_P HELX_P16 AB7 ARG C 242 ? ASN C 255 ? ARG A 242 ASN A 255 1 ? 14 
HELX_P HELX_P17 AB8 LYS C 270 ? SER C 281 ? LYS A 270 SER A 281 1 ? 12 
HELX_P HELX_P18 AB9 THR C 295 ? ASP C 309 ? THR A 295 ASP A 309 1 ? 15 
HELX_P HELX_P19 AC1 LYS C 330 ? GLY C 352 ? LYS A 330 GLY A 352 1 ? 23 
HELX_P HELX_P20 AC2 ARG D 8   ? ALA D 26  ? ARG B 8   ALA B 26  1 ? 19 
HELX_P HELX_P21 AC3 THR D 29  ? THR D 34  ? THR B 29  THR B 34  1 ? 6  
HELX_P HELX_P22 AC4 ARG E 13  ? ASN E 24  ? ARG C 13  ASN C 24  1 ? 12 
HELX_P HELX_P23 AC5 LYS E 29  ? ALA E 45  ? LYS C 29  ALA C 45  1 ? 17 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 110 SG ? ? ? 1_555 A CYS 187 SG ? ? R CYS 110 R CYS 187 1_555 ? ? ? ? ? ? ? 2.033 ? ? 
disulf2 disulf ? ? B CYS 57  SG ? ? ? 1_555 B CYS 67  SG ? ? L CYS 77  L CYS 87  1_555 ? ? ? ? ? ? ? 2.031 ? ? 
disulf3 disulf ? ? B CYS 78  SG ? ? ? 1_555 B CYS 97  SG ? ? L CYS 98  L CYS 117 1_555 ? ? ? ? ? ? ? 2.031 ? ? 
disulf4 disulf ? ? B CYS 81  SG ? ? ? 1_555 B CYS 115 SG ? ? L CYS 101 L CYS 135 1_555 ? ? ? ? ? ? ? 2.032 ? ? 
disulf5 disulf ? ? D CYS 121 SG ? ? ? 1_555 D CYS 149 SG ? ? B CYS 121 B CYS 149 1_555 ? ? ? ? ? ? ? 2.037 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 110 ? CYS A 187 ? CYS R 110 ? 1_555 CYS R 187 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS B 57  ? CYS B 67  ? CYS L 77  ? 1_555 CYS L 87  ? 1_555 SG SG . . . None 'Disulfide bridge' 
3 CYS B 78  ? CYS B 97  ? CYS L 98  ? 1_555 CYS L 117 ? 1_555 SG SG . . . None 'Disulfide bridge' 
4 CYS B 81  ? CYS B 115 ? CYS L 101 ? 1_555 CYS L 135 ? 1_555 SG SG . . . None 'Disulfide bridge' 
5 CYS D 121 ? CYS D 149 ? CYS B 121 ? 1_555 CYS B 149 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 6 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 4 ? 
AA7 ? 4 ? 
AA8 ? 4 ? 
AA9 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? parallel      
AA2 3 4 ? parallel      
AA2 4 5 ? parallel      
AA2 5 6 ? parallel      
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ASP A 177 ? THR A 178 ? ASP R 177 THR R 178 
AA1 2 CYS A 187 ? TYR A 188 ? CYS R 187 TYR R 188 
AA2 1 ILE C 184 ? THR C 190 ? ILE A 184 THR A 190 
AA2 2 HIS C 195 ? VAL C 201 ? HIS A 195 VAL A 201 
AA2 3 VAL C 34  ? LEU C 38  ? VAL A 34  LEU A 38  
AA2 4 ALA C 220 ? ALA C 226 ? ALA A 220 ALA A 226 
AA2 5 SER C 263 ? ASN C 269 ? SER A 263 ASN A 269 
AA2 6 ILE C 319 ? PHE C 323 ? ILE A 319 PHE A 323 
AA3 1 ARG D 46  ? LEU D 51  ? ARG B 46  LEU B 51  
AA3 2 LEU D 336 ? ASN D 340 ? LEU B 336 ASN B 340 
AA3 3 VAL D 327 ? GLY D 330 ? VAL B 327 GLY B 330 
AA3 4 CYS D 317 ? VAL D 320 ? CYS B 317 VAL B 320 
AA4 1 ILE D 58  ? TRP D 63  ? ILE B 58  TRP B 63  
AA4 2 LEU D 69  ? SER D 74  ? LEU B 69  SER B 74  
AA4 3 LYS D 78  ? ASP D 83  ? LYS B 78  ASP B 83  
AA4 4 ASN D 88  ? PRO D 94  ? ASN B 88  PRO B 94  
AA5 1 VAL D 100 ? TYR D 105 ? VAL B 100 TYR B 105 
AA5 2 TYR D 111 ? GLY D 116 ? TYR B 111 GLY B 116 
AA5 3 ILE D 120 ? ASN D 125 ? ILE B 120 ASN B 125 
AA5 4 ARG D 134 ? ALA D 140 ? ARG B 134 ALA B 140 
AA6 1 LEU D 146 ? PHE D 151 ? LEU B 146 PHE B 151 
AA6 2 ILE D 157 ? SER D 161 ? ILE B 157 SER B 161 
AA6 3 THR D 165 ? ASP D 170 ? THR B 165 ASP B 170 
AA6 4 GLN D 175 ? THR D 181 ? GLN B 175 THR B 181 
AA7 1 VAL D 187 ? LEU D 192 ? VAL B 187 LEU B 192 
AA7 2 LEU D 198 ? ALA D 203 ? LEU B 198 ALA B 203 
AA7 3 SER D 207 ? ASP D 212 ? SER B 207 ASP B 212 
AA7 4 CYS D 218 ? THR D 223 ? CYS B 218 THR B 223 
AA8 1 ILE D 229 ? PHE D 234 ? ILE B 229 PHE B 234 
AA8 2 ALA D 240 ? SER D 245 ? ALA B 240 SER B 245 
AA8 3 THR D 249 ? ASP D 254 ? THR B 249 ASP B 254 
AA8 4 GLN D 259 ? SER D 265 ? GLN B 259 SER B 265 
AA9 1 ILE D 273 ? PHE D 278 ? ILE B 273 PHE B 278 
AA9 2 LEU D 284 ? TYR D 289 ? LEU B 284 TYR B 289 
AA9 3 CYS D 294 ? ASP D 298 ? CYS B 294 ASP B 298 
AA9 4 ARG D 304 ? VAL D 307 ? ARG B 304 VAL B 307 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ASP A 177 ? N ASP R 177 O TYR A 188 ? O TYR R 188 
AA2 1 2 N PHE C 189 ? N PHE A 189 O PHE C 196 ? O PHE A 196 
AA2 2 3 O HIS C 195 ? O HIS A 195 N VAL C 34  ? N VAL A 34  
AA2 3 4 N LEU C 37  ? N LEU A 37  O ILE C 222 ? O ILE A 222 
AA2 4 5 N PHE C 223 ? N PHE A 223 O PHE C 267 ? O PHE A 267 
AA2 5 6 N LEU C 268 ? N LEU A 268 O HIS C 322 ? O HIS A 322 
AA3 1 2 N ARG D 49  ? N ARG B 49  O ILE D 338 ? O ILE B 338 
AA3 2 3 O TRP D 339 ? O TRP B 339 N VAL D 327 ? N VAL B 327 
AA3 3 4 O GLY D 330 ? O GLY B 330 N CYS D 317 ? N CYS B 317 
AA4 1 2 N TYR D 59  ? N TYR B 59  O ALA D 73  ? O ALA B 73  
AA4 2 3 N LEU D 70  ? N LEU B 70  O TRP D 82  ? O TRP B 82  
AA4 3 4 N LEU D 79  ? N LEU B 79  O ILE D 93  ? O ILE B 93  
AA5 1 2 N ALA D 104 ? N ALA B 104 O ALA D 113 ? O ALA B 113 
AA5 2 3 N VAL D 112 ? N VAL B 112 O TYR D 124 ? O TYR B 124 
AA5 3 4 N ILE D 123 ? N ILE B 123 O ARG D 137 ? O ARG B 137 
AA6 1 2 N ARG D 150 ? N ARG B 150 O VAL D 158 ? O VAL B 158 
AA6 2 3 N THR D 159 ? N THR B 159 O ALA D 167 ? O ALA B 167 
AA6 3 4 N LEU D 168 ? N LEU B 168 O THR D 177 ? O THR B 177 
AA7 1 2 N MET D 188 ? N MET B 188 O GLY D 202 ? O GLY B 202 
AA7 2 3 N PHE D 199 ? N PHE B 199 O TRP D 211 ? O TRP B 211 
AA7 3 4 N LEU D 210 ? N LEU B 210 O GLN D 220 ? O GLN B 220 
AA8 1 2 N CYS D 233 ? N CYS B 233 O ALA D 242 ? O ALA B 242 
AA8 2 3 N PHE D 241 ? N PHE B 241 O PHE D 253 ? O PHE B 253 
AA8 3 4 N LEU D 252 ? N LEU B 252 O LEU D 261 ? O LEU B 261 
AA9 1 2 N SER D 275 ? N SER B 275 O GLY D 288 ? O GLY B 288 
AA9 2 3 N ALA D 287 ? N ALA B 287 O ASN D 295 ? O ASN B 295 
AA9 3 4 N VAL D 296 ? N VAL B 296 O GLY D 306 ? O GLY B 306 
# 
_pdbx_entry_details.entry_id                   9L3Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 OG R SER 114 ? ? OXT L SER 157 ? ? 2.17 
2 1 OH R TYR 215 ? ? OG1 R THR 260 ? ? 2.18 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 SER R 16  ? ? -124.16 -169.52 
2  1 MET R 99  ? ? -97.36  33.02   
3  1 GLN R 192 ? ? -170.77 -176.33 
4  1 LYS R 193 ? ? 68.16   -0.96   
5  1 TYR R 215 ? ? -130.15 -32.39  
6  1 VAL R 233 ? ? 38.20   38.81   
7  1 LYS R 234 ? ? 64.94   -0.89   
8  1 THR R 271 ? ? 68.12   -6.30   
9  1 ASP L 57  ? ? 62.91   165.20  
10 1 THR L 58  ? ? -150.83 79.15   
11 1 PHE L 60  ? ? -160.25 -57.29  
12 1 ALA L 62  ? ? 66.48   -172.16 
13 1 THR L 75  ? ? 56.03   -141.78 
14 1 TRP L 82  ? ? 65.36   163.33  
15 1 PHE L 150 ? ? 56.59   73.17   
16 1 GLN L 153 ? ? 70.94   -10.83  
17 1 GLU A 43  ? ? 65.58   -9.67   
18 1 GLN A 204 ? ? 60.68   63.33   
19 1 GLU A 216 ? ? -90.37  44.43   
20 1 ASN A 255 ? ? -93.59  53.97   
21 1 TYR A 287 ? ? 58.32   72.91   
22 1 PRO A 288 ? ? -66.19  -175.99 
23 1 LYS A 314 ? ? 67.30   -3.30   
24 1 CYS B 148 ? ? -160.74 115.87  
25 1 ASP B 247 ? ? -99.15  34.73   
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9L3Y 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9L3Y 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.6 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               59593 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'The full length chemerin bound GPR1-Gi complex' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3, 4, 5' 
# 
_em_imaging.entry_id                        9L3Y 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             1500 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9L3Y 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9L3Y 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 R MET 1   ? A MET 1   
2   1 Y 1 R GLU 2   ? A GLU 2   
3   1 Y 1 R ASP 3   ? A ASP 3   
4   1 Y 1 R LEU 4   ? A LEU 4   
5   1 Y 1 R GLU 5   ? A GLU 5   
6   1 Y 1 R GLU 6   ? A GLU 6   
7   1 Y 1 R THR 7   ? A THR 7   
8   1 Y 1 R LEU 8   ? A LEU 8   
9   1 Y 1 R PHE 9   ? A PHE 9   
10  1 Y 1 R GLU 10  ? A GLU 10  
11  1 Y 1 R GLU 11  ? A GLU 11  
12  1 Y 1 R GLU 29  ? A GLU 29  
13  1 Y 1 R GLU 30  ? A GLU 30  
14  1 Y 1 R LYS 31  ? A LYS 31  
15  1 Y 1 R VAL 32  ? A VAL 32  
16  1 Y 1 R GLN 33  ? A GLN 33  
17  1 Y 1 R LEU 34  ? A LEU 34  
18  1 Y 1 R ARG 316 ? A ARG 316 
19  1 Y 1 R SER 317 ? A SER 317 
20  1 Y 1 R SER 318 ? A SER 318 
21  1 Y 1 R VAL 319 ? A VAL 319 
22  1 Y 1 R ALA 320 ? A ALA 320 
23  1 Y 1 R GLU 321 ? A GLU 321 
24  1 Y 1 R ILE 322 ? A ILE 322 
25  1 Y 1 R GLU 323 ? A GLU 323 
26  1 Y 1 R PHE 324 ? A PHE 324 
27  1 Y 1 R LEU 325 ? A LEU 325 
28  1 Y 1 R GLU 326 ? A GLU 326 
29  1 Y 1 R VAL 327 ? A VAL 327 
30  1 Y 1 R LEU 328 ? A LEU 328 
31  1 Y 1 R PHE 329 ? A PHE 329 
32  1 Y 1 R GLN 330 ? A GLN 330 
33  1 Y 1 R GLY 331 ? A GLY 331 
34  1 Y 1 R PRO 332 ? A PRO 332 
35  1 Y 1 R TRP 333 ? A TRP 333 
36  1 Y 1 R SER 334 ? A SER 334 
37  1 Y 1 R HIS 335 ? A HIS 335 
38  1 Y 1 R PRO 336 ? A PRO 336 
39  1 Y 1 R GLN 337 ? A GLN 337 
40  1 Y 1 R PHE 338 ? A PHE 338 
41  1 Y 1 R GLU 339 ? A GLU 339 
42  1 Y 1 R LYS 340 ? A LYS 340 
43  1 Y 1 R GLY 341 ? A GLY 341 
44  1 Y 1 R GLY 342 ? A GLY 342 
45  1 Y 1 R GLY 343 ? A GLY 343 
46  1 Y 1 R SER 344 ? A SER 344 
47  1 Y 1 R GLY 345 ? A GLY 345 
48  1 Y 1 R GLY 346 ? A GLY 346 
49  1 Y 1 R GLY 347 ? A GLY 347 
50  1 Y 1 R SER 348 ? A SER 348 
51  1 Y 1 R GLY 349 ? A GLY 349 
52  1 Y 1 R GLY 350 ? A GLY 350 
53  1 Y 1 R SER 351 ? A SER 351 
54  1 Y 1 R ALA 352 ? A ALA 352 
55  1 Y 1 R TRP 353 ? A TRP 353 
56  1 Y 1 R SER 354 ? A SER 354 
57  1 Y 1 R HIS 355 ? A HIS 355 
58  1 Y 1 R PRO 356 ? A PRO 356 
59  1 Y 1 R GLN 357 ? A GLN 357 
60  1 Y 1 R PHE 358 ? A PHE 358 
61  1 Y 1 R GLU 359 ? A GLU 359 
62  1 Y 1 R LYS 360 ? A LYS 360 
63  1 Y 1 R ASP 361 ? A ASP 361 
64  1 Y 1 R TYR 362 ? A TYR 362 
65  1 Y 1 R LYS 363 ? A LYS 363 
66  1 Y 1 R ASP 364 ? A ASP 364 
67  1 Y 1 R ASP 365 ? A ASP 365 
68  1 Y 1 R ASP 366 ? A ASP 366 
69  1 Y 1 R ASP 367 ? A ASP 367 
70  1 Y 1 R LYS 368 ? A LYS 368 
71  1 Y 1 L GLU 21  ? B GLU 1   
72  1 Y 1 L LEU 22  ? B LEU 2   
73  1 Y 1 L PRO 42  ? B PRO 22  
74  1 Y 1 L VAL 43  ? B VAL 23  
75  1 Y 1 L GLN 44  ? B GLN 24  
76  1 Y 1 L PRO 91  ? B PRO 71  
77  1 Y 1 L ASN 92  ? B ASN 72  
78  1 Y 1 L GLY 93  ? B GLY 73  
79  1 Y 1 L ARG 94  ? B ARG 74  
80  1 Y 1 L LYS 95  ? B LYS 75  
81  1 Y 1 L ARG 96  ? B ARG 76  
82  1 Y 1 L LEU 104 ? B LEU 84  
83  1 Y 1 L GLY 105 ? B GLY 85  
84  1 Y 1 L SER 106 ? B SER 86  
85  1 Y 1 L GLU 107 ? B GLU 87  
86  1 Y 1 L ASP 108 ? B ASP 88  
87  1 Y 1 L PRO 118 ? B PRO 98  
88  1 Y 1 L ILE 119 ? B ILE 99  
89  1 Y 1 L GLU 120 ? B GLU 100 
90  1 Y 1 L THR 121 ? B THR 101 
91  1 Y 1 L GLN 122 ? B GLN 102 
92  1 Y 1 L VAL 123 ? B VAL 103 
93  1 Y 1 L LEU 124 ? B LEU 104 
94  1 Y 1 L ARG 125 ? B ARG 105 
95  1 Y 1 L GLU 126 ? B GLU 106 
96  1 Y 1 L ALA 127 ? B ALA 107 
97  1 Y 1 L GLU 128 ? B GLU 108 
98  1 Y 1 L GLU 129 ? B GLU 109 
99  1 Y 1 L HIS 130 ? B HIS 110 
100 1 Y 1 L GLN 131 ? B GLN 111 
101 1 Y 1 L GLU 132 ? B GLU 112 
102 1 Y 1 L GLU 143 ? B GLU 123 
103 1 Y 1 L ASP 144 ? B ASP 124 
104 1 Y 1 L PRO 145 ? B PRO 125 
105 1 Y 1 A MET 1   ? C MET 1   
106 1 Y 1 A GLY 2   ? C GLY 2   
107 1 Y 1 A CYS 3   ? C CYS 3   
108 1 Y 1 A THR 4   ? C THR 4   
109 1 Y 1 A LEU 5   ? C LEU 5   
110 1 Y 1 A LYS 54  ? C LYS 54  
111 1 Y 1 A ILE 55  ? C ILE 55  
112 1 Y 1 A ILE 56  ? C ILE 56  
113 1 Y 1 A HIS 57  ? C HIS 57  
114 1 Y 1 A GLU 58  ? C GLU 58  
115 1 Y 1 A ALA 59  ? C ALA 59  
116 1 Y 1 A GLY 60  ? C GLY 60  
117 1 Y 1 A TYR 61  ? C TYR 61  
118 1 Y 1 A SER 62  ? C SER 62  
119 1 Y 1 A GLU 63  ? C GLU 63  
120 1 Y 1 A GLU 64  ? C GLU 64  
121 1 Y 1 A GLU 65  ? C GLU 65  
122 1 Y 1 A CYS 66  ? C CYS 66  
123 1 Y 1 A LYS 67  ? C LYS 67  
124 1 Y 1 A GLN 68  ? C GLN 68  
125 1 Y 1 A TYR 69  ? C TYR 69  
126 1 Y 1 A LYS 70  ? C LYS 70  
127 1 Y 1 A ALA 71  ? C ALA 71  
128 1 Y 1 A VAL 72  ? C VAL 72  
129 1 Y 1 A VAL 73  ? C VAL 73  
130 1 Y 1 A TYR 74  ? C TYR 74  
131 1 Y 1 A SER 75  ? C SER 75  
132 1 Y 1 A ASN 76  ? C ASN 76  
133 1 Y 1 A THR 77  ? C THR 77  
134 1 Y 1 A ILE 78  ? C ILE 78  
135 1 Y 1 A GLN 79  ? C GLN 79  
136 1 Y 1 A SER 80  ? C SER 80  
137 1 Y 1 A ILE 81  ? C ILE 81  
138 1 Y 1 A ILE 82  ? C ILE 82  
139 1 Y 1 A ALA 83  ? C ALA 83  
140 1 Y 1 A ILE 84  ? C ILE 84  
141 1 Y 1 A ILE 85  ? C ILE 85  
142 1 Y 1 A ARG 86  ? C ARG 86  
143 1 Y 1 A ALA 87  ? C ALA 87  
144 1 Y 1 A MET 88  ? C MET 88  
145 1 Y 1 A GLY 89  ? C GLY 89  
146 1 Y 1 A ARG 90  ? C ARG 90  
147 1 Y 1 A LEU 91  ? C LEU 91  
148 1 Y 1 A LYS 92  ? C LYS 92  
149 1 Y 1 A ILE 93  ? C ILE 93  
150 1 Y 1 A ASP 94  ? C ASP 94  
151 1 Y 1 A PHE 95  ? C PHE 95  
152 1 Y 1 A GLY 96  ? C GLY 96  
153 1 Y 1 A ASP 97  ? C ASP 97  
154 1 Y 1 A SER 98  ? C SER 98  
155 1 Y 1 A ALA 99  ? C ALA 99  
156 1 Y 1 A ARG 100 ? C ARG 100 
157 1 Y 1 A ALA 101 ? C ALA 101 
158 1 Y 1 A ASP 102 ? C ASP 102 
159 1 Y 1 A ASP 103 ? C ASP 103 
160 1 Y 1 A ALA 104 ? C ALA 104 
161 1 Y 1 A ARG 105 ? C ARG 105 
162 1 Y 1 A GLN 106 ? C GLN 106 
163 1 Y 1 A LEU 107 ? C LEU 107 
164 1 Y 1 A PHE 108 ? C PHE 108 
165 1 Y 1 A VAL 109 ? C VAL 109 
166 1 Y 1 A LEU 110 ? C LEU 110 
167 1 Y 1 A ALA 111 ? C ALA 111 
168 1 Y 1 A GLY 112 ? C GLY 112 
169 1 Y 1 A ALA 113 ? C ALA 113 
170 1 Y 1 A ALA 114 ? C ALA 114 
171 1 Y 1 A GLU 115 ? C GLU 115 
172 1 Y 1 A GLU 116 ? C GLU 116 
173 1 Y 1 A GLY 117 ? C GLY 117 
174 1 Y 1 A PHE 118 ? C PHE 118 
175 1 Y 1 A MET 119 ? C MET 119 
176 1 Y 1 A THR 120 ? C THR 120 
177 1 Y 1 A ALA 121 ? C ALA 121 
178 1 Y 1 A GLU 122 ? C GLU 122 
179 1 Y 1 A LEU 123 ? C LEU 123 
180 1 Y 1 A ALA 124 ? C ALA 124 
181 1 Y 1 A GLY 125 ? C GLY 125 
182 1 Y 1 A VAL 126 ? C VAL 126 
183 1 Y 1 A ILE 127 ? C ILE 127 
184 1 Y 1 A LYS 128 ? C LYS 128 
185 1 Y 1 A ARG 129 ? C ARG 129 
186 1 Y 1 A LEU 130 ? C LEU 130 
187 1 Y 1 A TRP 131 ? C TRP 131 
188 1 Y 1 A LYS 132 ? C LYS 132 
189 1 Y 1 A ASP 133 ? C ASP 133 
190 1 Y 1 A SER 134 ? C SER 134 
191 1 Y 1 A GLY 135 ? C GLY 135 
192 1 Y 1 A VAL 136 ? C VAL 136 
193 1 Y 1 A GLN 137 ? C GLN 137 
194 1 Y 1 A ALA 138 ? C ALA 138 
195 1 Y 1 A CYS 139 ? C CYS 139 
196 1 Y 1 A PHE 140 ? C PHE 140 
197 1 Y 1 A ASN 141 ? C ASN 141 
198 1 Y 1 A ARG 142 ? C ARG 142 
199 1 Y 1 A SER 143 ? C SER 143 
200 1 Y 1 A ARG 144 ? C ARG 144 
201 1 Y 1 A GLU 145 ? C GLU 145 
202 1 Y 1 A TYR 146 ? C TYR 146 
203 1 Y 1 A GLN 147 ? C GLN 147 
204 1 Y 1 A LEU 148 ? C LEU 148 
205 1 Y 1 A ASN 149 ? C ASN 149 
206 1 Y 1 A ASP 150 ? C ASP 150 
207 1 Y 1 A SER 151 ? C SER 151 
208 1 Y 1 A ALA 152 ? C ALA 152 
209 1 Y 1 A ALA 153 ? C ALA 153 
210 1 Y 1 A TYR 154 ? C TYR 154 
211 1 Y 1 A TYR 155 ? C TYR 155 
212 1 Y 1 A LEU 156 ? C LEU 156 
213 1 Y 1 A ASN 157 ? C ASN 157 
214 1 Y 1 A ASP 158 ? C ASP 158 
215 1 Y 1 A LEU 159 ? C LEU 159 
216 1 Y 1 A ASP 160 ? C ASP 160 
217 1 Y 1 A ARG 161 ? C ARG 161 
218 1 Y 1 A ILE 162 ? C ILE 162 
219 1 Y 1 A ALA 163 ? C ALA 163 
220 1 Y 1 A GLN 164 ? C GLN 164 
221 1 Y 1 A PRO 165 ? C PRO 165 
222 1 Y 1 A ASN 166 ? C ASN 166 
223 1 Y 1 A TYR 167 ? C TYR 167 
224 1 Y 1 A ILE 168 ? C ILE 168 
225 1 Y 1 A PRO 169 ? C PRO 169 
226 1 Y 1 A THR 170 ? C THR 170 
227 1 Y 1 A GLN 171 ? C GLN 171 
228 1 Y 1 A GLN 172 ? C GLN 172 
229 1 Y 1 A ASP 173 ? C ASP 173 
230 1 Y 1 A VAL 174 ? C VAL 174 
231 1 Y 1 A LEU 175 ? C LEU 175 
232 1 Y 1 A ARG 176 ? C ARG 176 
233 1 Y 1 A THR 177 ? C THR 177 
234 1 Y 1 A ARG 178 ? C ARG 178 
235 1 Y 1 A VAL 179 ? C VAL 179 
236 1 Y 1 A LYS 180 ? C LYS 180 
237 1 Y 1 A THR 181 ? C THR 181 
238 1 Y 1 A ALA 235 ? C ALA 235 
239 1 Y 1 A GLU 236 ? C GLU 236 
240 1 Y 1 A ASP 237 ? C ASP 237 
241 1 Y 1 A GLU 238 ? C GLU 238 
242 1 Y 1 A GLU 239 ? C GLU 239 
243 1 Y 1 A MET 240 ? C MET 240 
244 1 Y 1 A CYS 325 ? C CYS 325 
245 1 Y 1 A SER 326 ? C SER 326 
246 1 Y 1 A THR 327 ? C THR 327 
247 1 Y 1 A ASP 328 ? C ASP 328 
248 1 Y 1 B MET 1   ? D MET 1   
249 1 Y 1 B SER 2   ? D SER 2   
250 1 Y 1 B GLU 3   ? D GLU 3   
251 1 Y 1 B LEU 4   ? D LEU 4   
252 1 Y 1 B ASP 5   ? D ASP 5   
253 1 Y 1 B GLN 6   ? D GLN 6   
254 1 Y 1 B ARG 129 ? D ARG 129 
255 1 Y 1 B GLU 130 ? D GLU 130 
256 1 Y 1 B GLY 131 ? D GLY 131 
257 1 Y 1 B ASN 132 ? D ASN 132 
258 1 Y 1 C MET 1   ? E MET 1   
259 1 Y 1 C ALA 2   ? E ALA 2   
260 1 Y 1 C SER 3   ? E SER 3   
261 1 Y 1 C ASN 4   ? E ASN 4   
262 1 Y 1 C ASN 5   ? E ASN 5   
263 1 Y 1 C THR 6   ? E THR 6   
264 1 Y 1 C ALA 7   ? E ALA 7   
265 1 Y 1 C SER 8   ? E SER 8   
266 1 Y 1 C ILE 9   ? E ILE 9   
267 1 Y 1 C ALA 10  ? E ALA 10  
268 1 Y 1 C GLN 11  ? E GLN 11  
269 1 Y 1 C GLU 63  ? E GLU 63  
270 1 Y 1 C LYS 64  ? E LYS 64  
271 1 Y 1 C LYS 65  ? E LYS 65  
272 1 Y 1 C PHE 66  ? E PHE 66  
273 1 Y 1 C PHE 67  ? E PHE 67  
274 1 Y 1 C CYS 68  ? E CYS 68  
275 1 Y 1 C ALA 69  ? E ALA 69  
276 1 Y 1 C ILE 70  ? E ILE 70  
277 1 Y 1 C LEU 71  ? E LEU 71  
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-12-19 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           9L3Y 
_em_admin.last_update        2025-06-11 
_em_admin.map_release_date   2025-03-12 
_em_admin.title              'Cryo-EM structure of the G-protein coupled receptor 1 (GPR1) in complex with chemerin and Gi1' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     NONE 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   1 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   1 
_em_entity_assembly_recombinant.ncbi_tax_id          7108 
_em_entity_assembly_recombinant.organism             'Spodoptera frugiperda' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         70 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ?      ?           
'MODEL REFINEMENT'         ? 2  ? ? ? PHENIX 1.19.2_4158 
'IMAGE ACQUISITION'        ? 3  ? ? 1 ?      ?           
MASKING                    ? 4  ? ? ? ?      ?           
'CTF CORRECTION'           ? 5  1 ? ? ?      ?           
'LAYERLINE INDEXING'       ? 6  ? ? ? ?      ?           
'DIFFRACTION INDEXING'     ? 7  ? ? ? ?      ?           
'MODEL FITTING'            ? 8  ? ? ? ?      ?           
OTHER                      ? 9  ? ? ? ?      ?           
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ?      ?           
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ?      ?           
CLASSIFICATION             ? 12 1 ? ? ?      ?           
RECONSTRUCTION             ? 13 1 ? ? ?      ?           
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Science Foundation (NSF, China)'            China 2022YFA1302900 1 
'National Natural Science Foundation of China (NSFC)' China 82121005       2 
'National Natural Science Foundation of China (NSFC)' China 32401012       3 
# 
_atom_sites.entry_id                    9L3Y 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . PHE A 1 12  ? 153.280 102.093 193.003 1.00 114.61 ? 12  PHE R N   1 
ATOM 2    C CA  . PHE A 1 12  ? 152.764 103.419 193.325 1.00 114.61 ? 12  PHE R CA  1 
ATOM 3    C C   . PHE A 1 12  ? 153.700 104.508 192.813 1.00 114.61 ? 12  PHE R C   1 
ATOM 4    O O   . PHE A 1 12  ? 154.340 105.207 193.598 1.00 114.61 ? 12  PHE R O   1 
ATOM 5    C CB  . PHE A 1 12  ? 152.562 103.566 194.835 1.00 114.61 ? 12  PHE R CB  1 
ATOM 6    C CG  . PHE A 1 12  ? 151.432 102.740 195.382 1.00 114.61 ? 12  PHE R CG  1 
ATOM 7    C CD1 . PHE A 1 12  ? 150.470 102.209 194.537 1.00 114.61 ? 12  PHE R CD1 1 
ATOM 8    C CD2 . PHE A 1 12  ? 151.332 102.494 196.741 1.00 114.61 ? 12  PHE R CD2 1 
ATOM 9    C CE1 . PHE A 1 12  ? 149.429 101.449 195.039 1.00 114.61 ? 12  PHE R CE1 1 
ATOM 10   C CE2 . PHE A 1 12  ? 150.294 101.735 197.249 1.00 114.61 ? 12  PHE R CE2 1 
ATOM 11   C CZ  . PHE A 1 12  ? 149.342 101.212 196.396 1.00 114.61 ? 12  PHE R CZ  1 
ATOM 12   N N   . GLU A 1 13  ? 153.774 104.649 191.492 1.00 107.41 ? 13  GLU R N   1 
ATOM 13   C CA  . GLU A 1 13  ? 154.638 105.641 190.866 1.00 107.41 ? 13  GLU R CA  1 
ATOM 14   C C   . GLU A 1 13  ? 153.822 106.485 189.901 1.00 107.41 ? 13  GLU R C   1 
ATOM 15   O O   . GLU A 1 13  ? 153.131 105.945 189.032 1.00 107.41 ? 13  GLU R O   1 
ATOM 16   C CB  . GLU A 1 13  ? 155.805 104.975 190.126 1.00 107.41 ? 13  GLU R CB  1 
ATOM 17   C CG  . GLU A 1 13  ? 156.944 104.540 191.029 1.00 107.41 ? 13  GLU R CG  1 
ATOM 18   C CD  . GLU A 1 13  ? 158.131 104.004 190.255 1.00 107.41 ? 13  GLU R CD  1 
ATOM 19   O OE1 . GLU A 1 13  ? 157.998 103.791 189.031 1.00 107.41 ? 13  GLU R OE1 1 
ATOM 20   O OE2 . GLU A 1 13  ? 159.199 103.798 190.869 1.00 107.41 ? 13  GLU R OE2 1 
ATOM 21   N N   . ASN A 1 14  ? 153.905 107.806 190.058 1.00 108.87 ? 14  ASN R N   1 
ATOM 22   C CA  . ASN A 1 14  ? 153.242 108.734 189.154 1.00 108.87 ? 14  ASN R CA  1 
ATOM 23   C C   . ASN A 1 14  ? 154.191 109.373 188.151 1.00 108.87 ? 14  ASN R C   1 
ATOM 24   O O   . ASN A 1 14  ? 153.725 109.953 187.164 1.00 108.87 ? 14  ASN R O   1 
ATOM 25   C CB  . ASN A 1 14  ? 152.537 109.840 189.950 1.00 108.87 ? 14  ASN R CB  1 
ATOM 26   C CG  . ASN A 1 14  ? 151.428 109.305 190.834 1.00 108.87 ? 14  ASN R CG  1 
ATOM 27   O OD1 . ASN A 1 14  ? 151.506 109.378 192.060 1.00 108.87 ? 14  ASN R OD1 1 
ATOM 28   N ND2 . ASN A 1 14  ? 150.386 108.764 190.214 1.00 108.87 ? 14  ASN R ND2 1 
ATOM 29   N N   . TYR A 1 15  ? 155.496 109.278 188.375 1.00 107.27 ? 15  TYR R N   1 
ATOM 30   C CA  . TYR A 1 15  ? 156.490 109.899 187.509 1.00 107.27 ? 15  TYR R CA  1 
ATOM 31   C C   . TYR A 1 15  ? 157.744 109.029 187.530 1.00 107.27 ? 15  TYR R C   1 
ATOM 32   O O   . TYR A 1 15  ? 157.692 107.851 187.897 1.00 107.27 ? 15  TYR R O   1 
ATOM 33   C CB  . TYR A 1 15  ? 156.757 111.350 187.946 1.00 107.27 ? 15  TYR R CB  1 
ATOM 34   C CG  . TYR A 1 15  ? 155.649 112.312 187.582 1.00 107.27 ? 15  TYR R CG  1 
ATOM 35   C CD1 . TYR A 1 15  ? 155.503 112.770 186.279 1.00 107.27 ? 15  TYR R CD1 1 
ATOM 36   C CD2 . TYR A 1 15  ? 154.749 112.760 188.539 1.00 107.27 ? 15  TYR R CD2 1 
ATOM 37   C CE1 . TYR A 1 15  ? 154.492 113.649 185.940 1.00 107.27 ? 15  TYR R CE1 1 
ATOM 38   C CE2 . TYR A 1 15  ? 153.734 113.639 188.209 1.00 107.27 ? 15  TYR R CE2 1 
ATOM 39   C CZ  . TYR A 1 15  ? 153.611 114.080 186.909 1.00 107.27 ? 15  TYR R CZ  1 
ATOM 40   O OH  . TYR A 1 15  ? 152.603 114.955 186.574 1.00 107.27 ? 15  TYR R OH  1 
ATOM 41   N N   . SER A 1 16  ? 158.871 109.611 187.135 1.00 111.92 ? 16  SER R N   1 
ATOM 42   C CA  . SER A 1 16  ? 160.134 108.888 187.045 1.00 111.92 ? 16  SER R CA  1 
ATOM 43   C C   . SER A 1 16  ? 161.158 109.630 187.901 1.00 111.92 ? 16  SER R C   1 
ATOM 44   O O   . SER A 1 16  ? 160.823 110.526 188.686 1.00 111.92 ? 16  SER R O   1 
ATOM 45   C CB  . SER A 1 16  ? 160.570 108.744 185.582 1.00 111.92 ? 16  SER R CB  1 
ATOM 46   O OG  . SER A 1 16  ? 159.733 107.836 184.887 1.00 111.92 ? 16  SER R OG  1 
ATOM 47   N N   . TYR A 1 17  ? 162.428 109.239 187.770 1.00 113.48 ? 17  TYR R N   1 
ATOM 48   C CA  . TYR A 1 17  ? 163.515 109.822 188.549 1.00 113.48 ? 17  TYR R CA  1 
ATOM 49   C C   . TYR A 1 17  ? 163.549 111.341 188.422 1.00 113.48 ? 17  TYR R C   1 
ATOM 50   O O   . TYR A 1 17  ? 163.859 112.043 189.390 1.00 113.48 ? 17  TYR R O   1 
ATOM 51   C CB  . TYR A 1 17  ? 164.858 109.228 188.116 1.00 113.48 ? 17  TYR R CB  1 
ATOM 52   N N   . ASP A 1 18  ? 163.229 111.856 187.238 1.00 112.68 ? 18  ASP R N   1 
ATOM 53   C CA  . ASP A 1 18  ? 163.137 113.291 186.995 1.00 112.68 ? 18  ASP R CA  1 
ATOM 54   C C   . ASP A 1 18  ? 161.666 113.686 187.061 1.00 112.68 ? 18  ASP R C   1 
ATOM 55   O O   . ASP A 1 18  ? 160.893 113.377 186.147 1.00 112.68 ? 18  ASP R O   1 
ATOM 56   C CB  . ASP A 1 18  ? 163.752 113.662 185.647 1.00 112.68 ? 18  ASP R CB  1 
ATOM 57   C CG  . ASP A 1 18  ? 165.258 113.493 185.629 1.00 112.68 ? 18  ASP R CG  1 
ATOM 58   O OD1 . ASP A 1 18  ? 165.887 113.636 186.699 1.00 112.68 ? 18  ASP R OD1 1 
ATOM 59   O OD2 . ASP A 1 18  ? 165.814 113.217 184.545 1.00 112.68 ? 18  ASP R OD2 1 
ATOM 60   N N   . LEU A 1 19  ? 161.284 114.364 188.139 1.00 105.86 ? 19  LEU R N   1 
ATOM 61   C CA  . LEU A 1 19  ? 159.897 114.760 188.347 1.00 105.86 ? 19  LEU R CA  1 
ATOM 62   C C   . LEU A 1 19  ? 159.621 116.057 187.595 1.00 105.86 ? 19  LEU R C   1 
ATOM 63   O O   . LEU A 1 19  ? 160.124 117.120 187.976 1.00 105.86 ? 19  LEU R O   1 
ATOM 64   C CB  . LEU A 1 19  ? 159.604 114.927 189.837 1.00 105.86 ? 19  LEU R CB  1 
ATOM 65   C CG  . LEU A 1 19  ? 159.390 113.672 190.692 1.00 105.86 ? 19  LEU R CG  1 
ATOM 66   C CD1 . LEU A 1 19  ? 160.689 112.910 190.919 1.00 105.86 ? 19  LEU R CD1 1 
ATOM 67   C CD2 . LEU A 1 19  ? 158.750 114.036 192.023 1.00 105.86 ? 19  LEU R CD2 1 
ATOM 68   N N   . ASP A 1 20  ? 158.821 115.972 186.535 1.00 101.45 ? 20  ASP R N   1 
ATOM 69   C CA  . ASP A 1 20  ? 158.508 117.120 185.698 1.00 101.45 ? 20  ASP R CA  1 
ATOM 70   C C   . ASP A 1 20  ? 157.003 117.222 185.495 1.00 101.45 ? 20  ASP R C   1 
ATOM 71   O O   . ASP A 1 20  ? 156.312 116.214 185.322 1.00 101.45 ? 20  ASP R O   1 
ATOM 72   C CB  . ASP A 1 20  ? 159.210 117.031 184.335 1.00 101.45 ? 20  ASP R CB  1 
ATOM 73   C CG  . ASP A 1 20  ? 160.608 117.618 184.358 1.00 101.45 ? 20  ASP R CG  1 
ATOM 74   O OD1 . ASP A 1 20  ? 161.094 117.960 185.457 1.00 101.45 ? 20  ASP R OD1 1 
ATOM 75   O OD2 . ASP A 1 20  ? 161.221 117.739 183.277 1.00 101.45 ? 20  ASP R OD2 1 
ATOM 76   N N   . TYR A 1 21  ? 156.508 118.452 185.516 1.00 94.47  ? 21  TYR R N   1 
ATOM 77   C CA  . TYR A 1 21  ? 155.094 118.760 185.315 1.00 94.47  ? 21  TYR R CA  1 
ATOM 78   C C   . TYR A 1 21  ? 155.002 120.257 185.040 1.00 94.47  ? 21  TYR R C   1 
ATOM 79   O O   . TYR A 1 21  ? 156.022 120.925 184.835 1.00 94.47  ? 21  TYR R O   1 
ATOM 80   C CB  . TYR A 1 21  ? 154.254 118.336 186.522 1.00 94.47  ? 21  TYR R CB  1 
ATOM 81   C CG  . TYR A 1 21  ? 154.589 119.078 187.797 1.00 94.47  ? 21  TYR R CG  1 
ATOM 82   C CD1 . TYR A 1 21  ? 155.564 118.606 188.665 1.00 94.47  ? 21  TYR R CD1 1 
ATOM 83   C CD2 . TYR A 1 21  ? 153.902 120.233 188.151 1.00 94.47  ? 21  TYR R CD2 1 
ATOM 84   C CE1 . TYR A 1 21  ? 155.868 119.282 189.830 1.00 94.47  ? 21  TYR R CE1 1 
ATOM 85   C CE2 . TYR A 1 21  ? 154.195 120.909 189.318 1.00 94.47  ? 21  TYR R CE2 1 
ATOM 86   C CZ  . TYR A 1 21  ? 155.178 120.429 190.155 1.00 94.47  ? 21  TYR R CZ  1 
ATOM 87   O OH  . TYR A 1 21  ? 155.474 121.100 191.319 1.00 94.47  ? 21  TYR R OH  1 
ATOM 88   N N   . TYR A 1 22  ? 153.781 120.787 185.023 1.00 83.08  ? 22  TYR R N   1 
ATOM 89   C CA  . TYR A 1 22  ? 153.589 122.226 184.913 1.00 83.08  ? 22  TYR R CA  1 
ATOM 90   C C   . TYR A 1 22  ? 152.206 122.574 185.443 1.00 83.08  ? 22  TYR R C   1 
ATOM 91   O O   . TYR A 1 22  ? 151.241 121.847 185.196 1.00 83.08  ? 22  TYR R O   1 
ATOM 92   C CB  . TYR A 1 22  ? 153.748 122.708 183.466 1.00 83.08  ? 22  TYR R CB  1 
ATOM 93   C CG  . TYR A 1 22  ? 153.603 124.204 183.301 1.00 83.08  ? 22  TYR R CG  1 
ATOM 94   C CD1 . TYR A 1 22  ? 154.625 125.064 183.680 1.00 83.08  ? 22  TYR R CD1 1 
ATOM 95   C CD2 . TYR A 1 22  ? 152.448 124.756 182.764 1.00 83.08  ? 22  TYR R CD2 1 
ATOM 96   C CE1 . TYR A 1 22  ? 154.501 126.432 183.532 1.00 83.08  ? 22  TYR R CE1 1 
ATOM 97   C CE2 . TYR A 1 22  ? 152.315 126.124 182.611 1.00 83.08  ? 22  TYR R CE2 1 
ATOM 98   C CZ  . TYR A 1 22  ? 153.345 126.957 182.996 1.00 83.08  ? 22  TYR R CZ  1 
ATOM 99   O OH  . TYR A 1 22  ? 153.218 128.318 182.847 1.00 83.08  ? 22  TYR R OH  1 
ATOM 100  N N   . SER A 1 23  ? 152.120 123.688 186.173 1.00 78.18  ? 23  SER R N   1 
ATOM 101  C CA  . SER A 1 23  ? 150.856 124.120 186.769 1.00 78.18  ? 23  SER R CA  1 
ATOM 102  C C   . SER A 1 23  ? 150.937 125.629 186.985 1.00 78.18  ? 23  SER R C   1 
ATOM 103  O O   . SER A 1 23  ? 151.696 126.095 187.840 1.00 78.18  ? 23  SER R O   1 
ATOM 104  C CB  . SER A 1 23  ? 150.584 123.382 188.073 1.00 78.18  ? 23  SER R CB  1 
ATOM 105  O OG  . SER A 1 23  ? 149.381 123.831 188.672 1.00 78.18  ? 23  SER R OG  1 
ATOM 106  N N   . LEU A 1 24  ? 150.150 126.381 186.212 1.00 74.77  ? 24  LEU R N   1 
ATOM 107  C CA  . LEU A 1 24  ? 150.112 127.836 186.301 1.00 74.77  ? 24  LEU R CA  1 
ATOM 108  C C   . LEU A 1 24  ? 148.895 128.330 187.089 1.00 74.77  ? 24  LEU R C   1 
ATOM 109  O O   . LEU A 1 24  ? 148.275 129.339 186.725 1.00 74.77  ? 24  LEU R O   1 
ATOM 110  C CB  . LEU A 1 24  ? 150.161 128.435 184.890 1.00 74.77  ? 24  LEU R CB  1 
ATOM 111  C CG  . LEU A 1 24  ? 150.179 129.943 184.603 1.00 74.77  ? 24  LEU R CG  1 
ATOM 112  C CD1 . LEU A 1 24  ? 151.125 130.663 185.553 1.00 74.77  ? 24  LEU R CD1 1 
ATOM 113  C CD2 . LEU A 1 24  ? 150.555 130.216 183.155 1.00 74.77  ? 24  LEU R CD2 1 
ATOM 114  N N   . GLU A 1 25  ? 148.520 127.622 188.152 1.00 73.66  ? 25  GLU R N   1 
ATOM 115  C CA  . GLU A 1 25  ? 147.365 128.017 188.948 1.00 73.66  ? 25  GLU R CA  1 
ATOM 116  C C   . GLU A 1 25  ? 147.585 129.387 189.577 1.00 73.66  ? 25  GLU R C   1 
ATOM 117  O O   . GLU A 1 25  ? 148.659 129.682 190.110 1.00 73.66  ? 25  GLU R O   1 
ATOM 118  C CB  . GLU A 1 25  ? 147.091 126.978 190.036 1.00 73.66  ? 25  GLU R CB  1 
ATOM 119  C CG  . GLU A 1 25  ? 145.756 127.156 190.742 1.00 73.66  ? 25  GLU R CG  1 
ATOM 120  C CD  . GLU A 1 25  ? 144.662 126.291 190.148 1.00 73.66  ? 25  GLU R CD  1 
ATOM 121  O OE1 . GLU A 1 25  ? 144.979 125.420 189.311 1.00 73.66  ? 25  GLU R OE1 1 
ATOM 122  O OE2 . GLU A 1 25  ? 143.484 126.483 190.517 1.00 73.66  ? 25  GLU R OE2 1 
ATOM 123  N N   . SER A 1 26  ? 146.555 130.228 189.510 1.00 71.99  ? 26  SER R N   1 
ATOM 124  C CA  . SER A 1 26  ? 146.620 131.575 190.061 1.00 71.99  ? 26  SER R CA  1 
ATOM 125  C C   . SER A 1 26  ? 145.220 132.012 190.459 1.00 71.99  ? 26  SER R C   1 
ATOM 126  O O   . SER A 1 26  ? 144.276 131.861 189.678 1.00 71.99  ? 26  SER R O   1 
ATOM 127  C CB  . SER A 1 26  ? 147.219 132.558 189.050 1.00 71.99  ? 26  SER R CB  1 
ATOM 128  O OG  . SER A 1 26  ? 148.610 132.339 188.890 1.00 71.99  ? 26  SER R OG  1 
ATOM 129  N N   . ASP A 1 27  ? 145.090 132.551 191.674 1.00 71.30  ? 27  ASP R N   1 
ATOM 130  C CA  . ASP A 1 27  ? 143.784 132.996 192.147 1.00 71.30  ? 27  ASP R CA  1 
ATOM 131  C C   . ASP A 1 27  ? 143.350 134.291 191.472 1.00 71.30  ? 27  ASP R C   1 
ATOM 132  O O   . ASP A 1 27  ? 142.148 134.532 191.314 1.00 71.30  ? 27  ASP R O   1 
ATOM 133  C CB  . ASP A 1 27  ? 143.807 133.172 193.665 1.00 71.30  ? 27  ASP R CB  1 
ATOM 134  N N   . LEU A 1 28  ? 144.300 135.129 191.070 1.00 69.75  ? 28  LEU R N   1 
ATOM 135  C CA  . LEU A 1 28  ? 143.982 136.392 190.414 1.00 69.75  ? 28  LEU R CA  1 
ATOM 136  C C   . LEU A 1 28  ? 143.446 136.160 189.005 1.00 69.75  ? 28  LEU R C   1 
ATOM 137  O O   . LEU A 1 28  ? 143.677 136.964 188.102 1.00 69.75  ? 28  LEU R O   1 
ATOM 138  C CB  . LEU A 1 28  ? 145.214 137.297 190.365 1.00 69.75  ? 28  LEU R CB  1 
ATOM 139  C CG  . LEU A 1 28  ? 145.883 137.611 191.704 1.00 69.75  ? 28  LEU R CG  1 
ATOM 140  C CD1 . LEU A 1 28  ? 147.223 138.296 191.486 1.00 69.75  ? 28  LEU R CD1 1 
ATOM 141  C CD2 . LEU A 1 28  ? 144.974 138.468 192.573 1.00 69.75  ? 28  LEU R CD2 1 
ATOM 142  N N   . GLY A 1 35  ? 126.935 133.420 179.752 1.00 54.34  ? 35  GLY R N   1 
ATOM 143  C CA  . GLY A 1 35  ? 125.556 132.974 179.810 1.00 54.34  ? 35  GLY R CA  1 
ATOM 144  C C   . GLY A 1 35  ? 124.656 133.671 178.809 1.00 54.34  ? 35  GLY R C   1 
ATOM 145  O O   . GLY A 1 35  ? 124.339 133.118 177.756 1.00 54.34  ? 35  GLY R O   1 
ATOM 146  N N   . VAL A 1 36  ? 124.240 134.895 179.144 1.00 56.30  ? 36  VAL R N   1 
ATOM 147  C CA  . VAL A 1 36  ? 123.378 135.657 178.245 1.00 56.30  ? 36  VAL R CA  1 
ATOM 148  C C   . VAL A 1 36  ? 124.128 136.038 176.974 1.00 56.30  ? 36  VAL R C   1 
ATOM 149  O O   . VAL A 1 36  ? 123.547 136.077 175.883 1.00 56.30  ? 36  VAL R O   1 
ATOM 150  C CB  . VAL A 1 36  ? 122.807 136.891 178.969 1.00 56.30  ? 36  VAL R CB  1 
ATOM 151  C CG1 . VAL A 1 36  ? 121.892 136.459 180.104 1.00 56.30  ? 36  VAL R CG1 1 
ATOM 152  C CG2 . VAL A 1 36  ? 123.928 137.773 179.502 1.00 56.30  ? 36  VAL R CG2 1 
ATOM 153  N N   . VAL A 1 37  ? 125.423 136.326 177.089 1.00 54.00  ? 37  VAL R N   1 
ATOM 154  C CA  . VAL A 1 37  ? 126.218 136.678 175.919 1.00 54.00  ? 37  VAL R CA  1 
ATOM 155  C C   . VAL A 1 37  ? 126.909 135.457 175.318 1.00 54.00  ? 37  VAL R C   1 
ATOM 156  O O   . VAL A 1 37  ? 127.118 135.403 174.101 1.00 54.00  ? 37  VAL R O   1 
ATOM 157  C CB  . VAL A 1 37  ? 127.241 137.768 176.284 1.00 54.00  ? 37  VAL R CB  1 
ATOM 158  C CG1 . VAL A 1 37  ? 127.893 138.334 175.030 1.00 54.00  ? 37  VAL R CG1 1 
ATOM 159  C CG2 . VAL A 1 37  ? 126.575 138.873 177.089 1.00 54.00  ? 37  VAL R CG2 1 
ATOM 160  N N   . HIS A 1 38  ? 127.266 134.472 176.146 1.00 51.00  ? 38  HIS R N   1 
ATOM 161  C CA  . HIS A 1 38  ? 127.963 133.293 175.642 1.00 51.00  ? 38  HIS R CA  1 
ATOM 162  C C   . HIS A 1 38  ? 127.093 132.504 174.670 1.00 51.00  ? 38  HIS R C   1 
ATOM 163  O O   . HIS A 1 38  ? 127.563 132.085 173.606 1.00 51.00  ? 38  HIS R O   1 
ATOM 164  C CB  . HIS A 1 38  ? 128.403 132.411 176.810 1.00 51.00  ? 38  HIS R CB  1 
ATOM 165  C CG  . HIS A 1 38  ? 129.601 131.565 176.514 1.00 51.00  ? 38  HIS R CG  1 
ATOM 166  N ND1 . HIS A 1 38  ? 129.686 130.757 175.401 1.00 51.00  ? 38  HIS R ND1 1 
ATOM 167  C CD2 . HIS A 1 38  ? 130.766 131.404 177.185 1.00 51.00  ? 38  HIS R CD2 1 
ATOM 168  C CE1 . HIS A 1 38  ? 130.851 130.134 175.400 1.00 51.00  ? 38  HIS R CE1 1 
ATOM 169  N NE2 . HIS A 1 38  ? 131.525 130.509 176.472 1.00 51.00  ? 38  HIS R NE2 1 
ATOM 170  N N   . TRP A 1 39  ? 125.820 132.298 175.015 1.00 51.34  ? 39  TRP R N   1 
ATOM 171  C CA  . TRP A 1 39  ? 124.930 131.529 174.149 1.00 51.34  ? 39  TRP R CA  1 
ATOM 172  C C   . TRP A 1 39  ? 124.693 132.239 172.822 1.00 51.34  ? 39  TRP R C   1 
ATOM 173  O O   . TRP A 1 39  ? 124.656 131.597 171.764 1.00 51.34  ? 39  TRP R O   1 
ATOM 174  C CB  . TRP A 1 39  ? 123.602 131.269 174.861 1.00 51.34  ? 39  TRP R CB  1 
ATOM 175  C CG  . TRP A 1 39  ? 123.717 130.374 176.060 1.00 51.34  ? 39  TRP R CG  1 
ATOM 176  C CD1 . TRP A 1 39  ? 124.862 129.857 176.593 1.00 51.34  ? 39  TRP R CD1 1 
ATOM 177  C CD2 . TRP A 1 39  ? 122.643 129.897 176.879 1.00 51.34  ? 39  TRP R CD2 1 
ATOM 178  N NE1 . TRP A 1 39  ? 124.567 129.085 177.691 1.00 51.34  ? 39  TRP R NE1 1 
ATOM 179  C CE2 . TRP A 1 39  ? 123.211 129.093 177.887 1.00 51.34  ? 39  TRP R CE2 1 
ATOM 180  C CE3 . TRP A 1 39  ? 121.255 130.070 176.856 1.00 51.34  ? 39  TRP R CE3 1 
ATOM 181  C CZ2 . TRP A 1 39  ? 122.441 128.464 178.863 1.00 51.34  ? 39  TRP R CZ2 1 
ATOM 182  C CZ3 . TRP A 1 39  ? 120.493 129.444 177.826 1.00 51.34  ? 39  TRP R CZ3 1 
ATOM 183  C CH2 . TRP A 1 39  ? 121.087 128.652 178.816 1.00 51.34  ? 39  TRP R CH2 1 
ATOM 184  N N   . VAL A 1 40  ? 124.526 133.564 172.861 1.00 47.29  ? 40  VAL R N   1 
ATOM 185  C CA  . VAL A 1 40  ? 124.254 134.324 171.645 1.00 47.29  ? 40  VAL R CA  1 
ATOM 186  C C   . VAL A 1 40  ? 125.419 134.210 170.671 1.00 47.29  ? 40  VAL R C   1 
ATOM 187  O O   . VAL A 1 40  ? 125.224 134.129 169.452 1.00 47.29  ? 40  VAL R O   1 
ATOM 188  C CB  . VAL A 1 40  ? 123.943 135.792 171.997 1.00 47.29  ? 40  VAL R CB  1 
ATOM 189  C CG1 . VAL A 1 40  ? 123.944 136.662 170.748 1.00 47.29  ? 40  VAL R CG1 1 
ATOM 190  C CG2 . VAL A 1 40  ? 122.607 135.891 172.717 1.00 47.29  ? 40  VAL R CG2 1 
ATOM 191  N N   . SER A 1 41  ? 126.649 134.195 171.191 1.00 47.76  ? 41  SER R N   1 
ATOM 192  C CA  . SER A 1 41  ? 127.819 134.076 170.326 1.00 47.76  ? 41  SER R CA  1 
ATOM 193  C C   . SER A 1 41  ? 127.806 132.760 169.557 1.00 47.76  ? 41  SER R C   1 
ATOM 194  O O   . SER A 1 41  ? 127.991 132.742 168.335 1.00 47.76  ? 41  SER R O   1 
ATOM 195  C CB  . SER A 1 41  ? 129.097 134.206 171.155 1.00 47.76  ? 41  SER R CB  1 
ATOM 196  O OG  . SER A 1 41  ? 129.164 135.469 171.794 1.00 47.76  ? 41  SER R OG  1 
ATOM 197  N N   . LEU A 1 42  ? 127.581 131.645 170.258 1.00 45.70  ? 42  LEU R N   1 
ATOM 198  C CA  . LEU A 1 42  ? 127.540 130.348 169.587 1.00 45.70  ? 42  LEU R CA  1 
ATOM 199  C C   . LEU A 1 42  ? 126.361 130.253 168.627 1.00 45.70  ? 42  LEU R C   1 
ATOM 200  O O   . LEU A 1 42  ? 126.474 129.644 167.557 1.00 45.70  ? 42  LEU R O   1 
ATOM 201  C CB  . LEU A 1 42  ? 127.494 129.212 170.611 1.00 45.70  ? 42  LEU R CB  1 
ATOM 202  C CG  . LEU A 1 42  ? 128.809 128.793 171.277 1.00 45.70  ? 42  LEU R CG  1 
ATOM 203  C CD1 . LEU A 1 42  ? 129.316 129.830 172.262 1.00 45.70  ? 42  LEU R CD1 1 
ATOM 204  C CD2 . LEU A 1 42  ? 128.646 127.443 171.960 1.00 45.70  ? 42  LEU R CD2 1 
ATOM 205  N N   . VAL A 1 43  ? 125.219 130.841 168.992 1.00 42.89  ? 43  VAL R N   1 
ATOM 206  C CA  . VAL A 1 43  ? 124.077 130.844 168.081 1.00 42.89  ? 43  VAL R CA  1 
ATOM 207  C C   . VAL A 1 43  ? 124.426 131.583 166.795 1.00 42.89  ? 43  VAL R C   1 
ATOM 208  O O   . VAL A 1 43  ? 124.137 131.110 165.688 1.00 42.89  ? 43  VAL R O   1 
ATOM 209  C CB  . VAL A 1 43  ? 122.842 131.455 168.771 1.00 42.89  ? 43  VAL R CB  1 
ATOM 210  C CG1 . VAL A 1 43  ? 121.774 131.802 167.745 1.00 42.89  ? 43  VAL R CG1 1 
ATOM 211  C CG2 . VAL A 1 43  ? 122.290 130.495 169.812 1.00 42.89  ? 43  VAL R CG2 1 
ATOM 212  N N   . LEU A 1 44  ? 125.061 132.750 166.920 1.00 39.88  ? 44  LEU R N   1 
ATOM 213  C CA  . LEU A 1 44  ? 125.462 133.508 165.741 1.00 39.88  ? 44  LEU R CA  1 
ATOM 214  C C   . LEU A 1 44  ? 126.488 132.749 164.910 1.00 39.88  ? 44  LEU R C   1 
ATOM 215  O O   . LEU A 1 44  ? 126.410 132.758 163.676 1.00 39.88  ? 44  LEU R O   1 
ATOM 216  C CB  . LEU A 1 44  ? 126.008 134.872 166.161 1.00 39.88  ? 44  LEU R CB  1 
ATOM 217  C CG  . LEU A 1 44  ? 126.386 135.841 165.042 1.00 39.88  ? 44  LEU R CG  1 
ATOM 218  C CD1 . LEU A 1 44  ? 125.166 136.173 164.202 1.00 39.88  ? 44  LEU R CD1 1 
ATOM 219  C CD2 . LEU A 1 44  ? 126.986 137.104 165.632 1.00 39.88  ? 44  LEU R CD2 1 
ATOM 220  N N   . TYR A 1 45  ? 127.445 132.082 165.563 1.00 41.75  ? 45  TYR R N   1 
ATOM 221  C CA  . TYR A 1 45  ? 128.412 131.268 164.833 1.00 41.75  ? 45  TYR R CA  1 
ATOM 222  C C   . TYR A 1 45  ? 127.717 130.158 164.052 1.00 41.75  ? 45  TYR R C   1 
ATOM 223  O O   . TYR A 1 45  ? 128.048 129.908 162.887 1.00 41.75  ? 45  TYR R O   1 
ATOM 224  C CB  . TYR A 1 45  ? 129.435 130.659 165.794 1.00 41.75  ? 45  TYR R CB  1 
ATOM 225  C CG  . TYR A 1 45  ? 130.489 131.608 166.319 1.00 41.75  ? 45  TYR R CG  1 
ATOM 226  C CD1 . TYR A 1 45  ? 131.294 132.335 165.455 1.00 41.75  ? 45  TYR R CD1 1 
ATOM 227  C CD2 . TYR A 1 45  ? 130.706 131.745 167.684 1.00 41.75  ? 45  TYR R CD2 1 
ATOM 228  C CE1 . TYR A 1 45  ? 132.266 133.190 165.937 1.00 41.75  ? 45  TYR R CE1 1 
ATOM 229  C CE2 . TYR A 1 45  ? 131.671 132.600 168.174 1.00 41.75  ? 45  TYR R CE2 1 
ATOM 230  C CZ  . TYR A 1 45  ? 132.449 133.320 167.296 1.00 41.75  ? 45  TYR R CZ  1 
ATOM 231  O OH  . TYR A 1 45  ? 133.416 134.172 167.780 1.00 41.75  ? 45  TYR R OH  1 
ATOM 232  N N   . CYS A 1 46  ? 126.755 129.479 164.683 1.00 45.30  ? 46  CYS R N   1 
ATOM 233  C CA  . CYS A 1 46  ? 126.055 128.385 164.017 1.00 45.30  ? 46  CYS R CA  1 
ATOM 234  C C   . CYS A 1 46  ? 125.238 128.884 162.832 1.00 45.30  ? 46  CYS R C   1 
ATOM 235  O O   . CYS A 1 46  ? 125.242 128.258 161.765 1.00 45.30  ? 46  CYS R O   1 
ATOM 236  C CB  . CYS A 1 46  ? 125.162 127.649 165.016 1.00 45.30  ? 46  CYS R CB  1 
ATOM 237  S SG  . CYS A 1 46  ? 126.067 126.689 166.252 1.00 45.30  ? 46  CYS R SG  1 
ATOM 238  N N   . LEU A 1 47  ? 124.524 130.001 162.997 1.00 42.56  ? 47  LEU R N   1 
ATOM 239  C CA  . LEU A 1 47  ? 123.770 130.553 161.872 1.00 42.56  ? 47  LEU R CA  1 
ATOM 240  C C   . LEU A 1 47  ? 124.692 130.999 160.743 1.00 42.56  ? 47  LEU R C   1 
ATOM 241  O O   . LEU A 1 47  ? 124.374 130.799 159.565 1.00 42.56  ? 47  LEU R O   1 
ATOM 242  C CB  . LEU A 1 47  ? 122.874 131.706 162.330 1.00 42.56  ? 47  LEU R CB  1 
ATOM 243  C CG  . LEU A 1 47  ? 121.498 131.391 162.935 1.00 42.56  ? 47  LEU R CG  1 
ATOM 244  C CD1 . LEU A 1 47  ? 120.622 130.727 161.883 1.00 42.56  ? 47  LEU R CD1 1 
ATOM 245  C CD2 . LEU A 1 47  ? 121.560 130.521 164.177 1.00 42.56  ? 47  LEU R CD2 1 
ATOM 246  N N   . ALA A 1 48  ? 125.838 131.598 161.077 1.00 41.65  ? 48  ALA R N   1 
ATOM 247  C CA  . ALA A 1 48  ? 126.786 131.996 160.041 1.00 41.65  ? 48  ALA R CA  1 
ATOM 248  C C   . ALA A 1 48  ? 127.325 130.783 159.293 1.00 41.65  ? 48  ALA R C   1 
ATOM 249  O O   . ALA A 1 48  ? 127.474 130.817 158.066 1.00 41.65  ? 48  ALA R O   1 
ATOM 250  C CB  . ALA A 1 48  ? 127.930 132.802 160.655 1.00 41.65  ? 48  ALA R CB  1 
ATOM 251  N N   . PHE A 1 49  ? 127.627 129.703 160.016 1.00 45.73  ? 49  PHE R N   1 
ATOM 252  C CA  . PHE A 1 49  ? 128.144 128.501 159.369 1.00 45.73  ? 49  PHE R CA  1 
ATOM 253  C C   . PHE A 1 49  ? 127.086 127.843 158.490 1.00 45.73  ? 49  PHE R C   1 
ATOM 254  O O   . PHE A 1 49  ? 127.393 127.374 157.388 1.00 45.73  ? 49  PHE R O   1 
ATOM 255  C CB  . PHE A 1 49  ? 128.658 127.521 160.423 1.00 45.73  ? 49  PHE R CB  1 
ATOM 256  C CG  . PHE A 1 49  ? 129.195 126.241 159.851 1.00 45.73  ? 49  PHE R CG  1 
ATOM 257  C CD1 . PHE A 1 49  ? 130.457 126.199 159.281 1.00 45.73  ? 49  PHE R CD1 1 
ATOM 258  C CD2 . PHE A 1 49  ? 128.442 125.079 159.886 1.00 45.73  ? 49  PHE R CD2 1 
ATOM 259  C CE1 . PHE A 1 49  ? 130.957 125.023 158.755 1.00 45.73  ? 49  PHE R CE1 1 
ATOM 260  C CE2 . PHE A 1 49  ? 128.936 123.900 159.361 1.00 45.73  ? 49  PHE R CE2 1 
ATOM 261  C CZ  . PHE A 1 49  ? 130.195 123.872 158.795 1.00 45.73  ? 49  PHE R CZ  1 
ATOM 262  N N   . VAL A 1 50  ? 125.838 127.792 158.962 1.00 45.28  ? 50  VAL R N   1 
ATOM 263  C CA  . VAL A 1 50  ? 124.768 127.185 158.174 1.00 45.28  ? 50  VAL R CA  1 
ATOM 264  C C   . VAL A 1 50  ? 124.493 128.004 156.919 1.00 45.28  ? 50  VAL R C   1 
ATOM 265  O O   . VAL A 1 50  ? 124.341 127.453 155.822 1.00 45.28  ? 50  VAL R O   1 
ATOM 266  C CB  . VAL A 1 50  ? 123.502 127.015 159.034 1.00 45.28  ? 50  VAL R CB  1 
ATOM 267  C CG1 . VAL A 1 50  ? 122.310 126.646 158.163 1.00 45.28  ? 50  VAL R CG1 1 
ATOM 268  C CG2 . VAL A 1 50  ? 123.727 125.956 160.102 1.00 45.28  ? 50  VAL R CG2 1 
ATOM 269  N N   . LEU A 1 51  ? 124.433 129.328 157.053 1.00 43.98  ? 51  LEU R N   1 
ATOM 270  C CA  . LEU A 1 51  ? 124.217 130.212 155.915 1.00 43.98  ? 51  LEU R CA  1 
ATOM 271  C C   . LEU A 1 51  ? 125.470 130.377 155.062 1.00 43.98  ? 51  LEU R C   1 
ATOM 272  O O   . LEU A 1 51  ? 125.405 131.000 153.996 1.00 43.98  ? 51  LEU R O   1 
ATOM 273  C CB  . LEU A 1 51  ? 123.721 131.576 156.416 1.00 43.98  ? 51  LEU R CB  1 
ATOM 274  C CG  . LEU A 1 51  ? 123.330 132.683 155.433 1.00 43.98  ? 51  LEU R CG  1 
ATOM 275  C CD1 . LEU A 1 51  ? 122.151 132.250 154.575 1.00 43.98  ? 51  LEU R CD1 1 
ATOM 276  C CD2 . LEU A 1 51  ? 123.017 133.975 156.172 1.00 43.98  ? 51  LEU R CD2 1 
ATOM 277  N N   . GLY A 1 52  ? 126.593 129.803 155.485 1.00 44.26  ? 52  GLY R N   1 
ATOM 278  C CA  . GLY A 1 52  ? 127.871 130.023 154.839 1.00 44.26  ? 52  GLY R CA  1 
ATOM 279  C C   . GLY A 1 52  ? 128.297 128.917 153.898 1.00 44.26  ? 52  GLY R C   1 
ATOM 280  O O   . GLY A 1 52  ? 127.907 128.913 152.726 1.00 44.26  ? 52  GLY R O   1 
ATOM 281  N N   . ILE A 1 53  ? 129.123 128.002 154.402 1.00 45.44  ? 53  ILE R N   1 
ATOM 282  C CA  . ILE A 1 53  ? 129.733 126.904 153.648 1.00 45.44  ? 53  ILE R CA  1 
ATOM 283  C C   . ILE A 1 53  ? 128.788 126.314 152.602 1.00 45.44  ? 53  ILE R C   1 
ATOM 284  O O   . ILE A 1 53  ? 129.213 126.125 151.454 1.00 45.44  ? 53  ILE R O   1 
ATOM 285  C CB  . ILE A 1 53  ? 130.251 125.812 154.601 1.00 45.44  ? 53  ILE R CB  1 
ATOM 286  C CG1 . ILE A 1 53  ? 131.417 126.344 155.435 1.00 45.44  ? 53  ILE R CG1 1 
ATOM 287  C CG2 . ILE A 1 53  ? 130.666 124.569 153.828 1.00 45.44  ? 53  ILE R CG2 1 
ATOM 288  C CD1 . ILE A 1 53  ? 132.635 126.703 154.615 1.00 45.44  ? 53  ILE R CD1 1 
ATOM 289  N N   . PRO A 1 54  ? 127.519 126.012 152.916 1.00 47.47  ? 54  PRO R N   1 
ATOM 290  C CA  . PRO A 1 54  ? 126.613 125.575 151.834 1.00 47.47  ? 54  PRO R CA  1 
ATOM 291  C C   . PRO A 1 54  ? 126.435 126.620 150.743 1.00 47.47  ? 54  PRO R C   1 
ATOM 292  O O   . PRO A 1 54  ? 126.581 126.305 149.554 1.00 47.47  ? 54  PRO R O   1 
ATOM 293  C CB  . PRO A 1 54  ? 125.302 125.285 152.577 1.00 47.47  ? 54  PRO R CB  1 
ATOM 294  C CG  . PRO A 1 54  ? 125.722 124.964 153.961 1.00 47.47  ? 54  PRO R CG  1 
ATOM 295  C CD  . PRO A 1 54  ? 126.870 125.885 154.235 1.00 47.47  ? 54  PRO R CD  1 
ATOM 296  N N   . GLY A 1 55  ? 126.126 127.864 151.118 1.00 46.85  ? 55  GLY R N   1 
ATOM 297  C CA  . GLY A 1 55  ? 125.929 128.900 150.116 1.00 46.85  ? 55  GLY R CA  1 
ATOM 298  C C   . GLY A 1 55  ? 127.192 129.218 149.340 1.00 46.85  ? 55  GLY R C   1 
ATOM 299  O O   . GLY A 1 55  ? 127.154 129.406 148.122 1.00 46.85  ? 55  GLY R O   1 
ATOM 300  N N   . ASN A 1 56  ? 128.331 129.283 150.034 1.00 44.25  ? 56  ASN R N   1 
ATOM 301  C CA  . ASN A 1 56  ? 129.594 129.550 149.353 1.00 44.25  ? 56  ASN R CA  1 
ATOM 302  C C   . ASN A 1 56  ? 129.962 128.416 148.404 1.00 44.25  ? 56  ASN R C   1 
ATOM 303  O O   . ASN A 1 56  ? 130.461 128.662 147.300 1.00 44.25  ? 56  ASN R O   1 
ATOM 304  C CB  . ASN A 1 56  ? 130.704 129.780 150.378 1.00 44.25  ? 56  ASN R CB  1 
ATOM 305  C CG  . ASN A 1 56  ? 130.540 131.085 151.128 1.00 44.25  ? 56  ASN R CG  1 
ATOM 306  O OD1 . ASN A 1 56  ? 130.199 132.112 150.542 1.00 44.25  ? 56  ASN R OD1 1 
ATOM 307  N ND2 . ASN A 1 56  ? 130.781 131.052 152.434 1.00 44.25  ? 56  ASN R ND2 1 
ATOM 308  N N   . ALA A 1 57  ? 129.725 127.166 148.814 1.00 48.04  ? 57  ALA R N   1 
ATOM 309  C CA  . ALA A 1 57  ? 129.983 126.036 147.929 1.00 48.04  ? 57  ALA R CA  1 
ATOM 310  C C   . ALA A 1 57  ? 129.069 126.070 146.712 1.00 48.04  ? 57  ALA R C   1 
ATOM 311  O O   . ALA A 1 57  ? 129.498 125.760 145.594 1.00 48.04  ? 57  ALA R O   1 
ATOM 312  C CB  . ALA A 1 57  ? 129.815 124.722 148.691 1.00 48.04  ? 57  ALA R CB  1 
ATOM 313  N N   . ILE A 1 58  ? 127.802 126.443 146.910 1.00 51.86  ? 58  ILE R N   1 
ATOM 314  C CA  . ILE A 1 58  ? 126.882 126.576 145.784 1.00 51.86  ? 58  ILE R CA  1 
ATOM 315  C C   . ILE A 1 58  ? 127.372 127.653 144.825 1.00 51.86  ? 58  ILE R C   1 
ATOM 316  O O   . ILE A 1 58  ? 127.357 127.470 143.602 1.00 51.86  ? 58  ILE R O   1 
ATOM 317  C CB  . ILE A 1 58  ? 125.456 126.870 146.288 1.00 51.86  ? 58  ILE R CB  1 
ATOM 318  C CG1 . ILE A 1 58  ? 124.849 125.621 146.929 1.00 51.86  ? 58  ILE R CG1 1 
ATOM 319  C CG2 . ILE A 1 58  ? 124.574 127.369 145.152 1.00 51.86  ? 58  ILE R CG2 1 
ATOM 320  C CD1 . ILE A 1 58  ? 124.711 124.453 145.978 1.00 51.86  ? 58  ILE R CD1 1 
ATOM 321  N N   . VAL A 1 59  ? 127.825 128.787 145.365 1.00 47.55  ? 59  VAL R N   1 
ATOM 322  C CA  . VAL A 1 59  ? 128.335 129.866 144.523 1.00 47.55  ? 59  VAL R CA  1 
ATOM 323  C C   . VAL A 1 59  ? 129.557 129.396 143.741 1.00 47.55  ? 59  VAL R C   1 
ATOM 324  O O   . VAL A 1 59  ? 129.683 129.655 142.539 1.00 47.55  ? 59  VAL R O   1 
ATOM 325  C CB  . VAL A 1 59  ? 128.651 131.109 145.375 1.00 47.55  ? 59  VAL R CB  1 
ATOM 326  C CG1 . VAL A 1 59  ? 129.471 132.112 144.577 1.00 47.55  ? 59  VAL R CG1 1 
ATOM 327  C CG2 . VAL A 1 59  ? 127.364 131.750 145.872 1.00 47.55  ? 59  VAL R CG2 1 
ATOM 328  N N   . ILE A 1 60  ? 130.468 128.686 144.410 1.00 50.78  ? 60  ILE R N   1 
ATOM 329  C CA  . ILE A 1 60  ? 131.675 128.202 143.743 1.00 50.78  ? 60  ILE R CA  1 
ATOM 330  C C   . ILE A 1 60  ? 131.318 127.234 142.621 1.00 50.78  ? 60  ILE R C   1 
ATOM 331  O O   . ILE A 1 60  ? 131.860 127.318 141.512 1.00 50.78  ? 60  ILE R O   1 
ATOM 332  C CB  . ILE A 1 60  ? 132.628 127.557 144.767 1.00 50.78  ? 60  ILE R CB  1 
ATOM 333  C CG1 . ILE A 1 60  ? 133.240 128.625 145.672 1.00 50.78  ? 60  ILE R CG1 1 
ATOM 334  C CG2 . ILE A 1 60  ? 133.724 126.773 144.064 1.00 50.78  ? 60  ILE R CG2 1 
ATOM 335  C CD1 . ILE A 1 60  ? 134.017 129.683 144.918 1.00 50.78  ? 60  ILE R CD1 1 
ATOM 336  N N   . TRP A 1 61  ? 130.398 126.305 142.886 1.00 57.14  ? 61  TRP R N   1 
ATOM 337  C CA  . TRP A 1 61  ? 130.046 125.301 141.890 1.00 57.14  ? 61  TRP R CA  1 
ATOM 338  C C   . TRP A 1 61  ? 129.195 125.865 140.760 1.00 57.14  ? 61  TRP R C   1 
ATOM 339  O O   . TRP A 1 61  ? 129.173 125.283 139.671 1.00 57.14  ? 61  TRP R O   1 
ATOM 340  C CB  . TRP A 1 61  ? 129.314 124.137 142.557 1.00 57.14  ? 61  TRP R CB  1 
ATOM 341  N N   . PHE A 1 62  ? 128.495 126.975 140.985 1.00 58.59  ? 62  PHE R N   1 
ATOM 342  C CA  . PHE A 1 62  ? 127.566 127.512 140.003 1.00 58.59  ? 62  PHE R CA  1 
ATOM 343  C C   . PHE A 1 62  ? 128.143 128.709 139.253 1.00 58.59  ? 62  PHE R C   1 
ATOM 344  O O   . PHE A 1 62  ? 127.632 129.059 138.185 1.00 58.59  ? 62  PHE R O   1 
ATOM 345  C CB  . PHE A 1 62  ? 126.241 127.843 140.725 1.00 58.59  ? 62  PHE R CB  1 
ATOM 346  C CG  . PHE A 1 62  ? 125.129 128.374 139.842 1.00 58.59  ? 62  PHE R CG  1 
ATOM 347  C CD1 . PHE A 1 62  ? 125.164 129.646 139.292 1.00 58.59  ? 62  PHE R CD1 1 
ATOM 348  C CD2 . PHE A 1 62  ? 124.039 127.567 139.555 1.00 58.59  ? 62  PHE R CD2 1 
ATOM 349  C CE1 . PHE A 1 62  ? 124.138 130.102 138.489 1.00 58.59  ? 62  PHE R CE1 1 
ATOM 350  C CE2 . PHE A 1 62  ? 123.012 128.020 138.752 1.00 58.59  ? 62  PHE R CE2 1 
ATOM 351  C CZ  . PHE A 1 62  ? 123.063 129.287 138.218 1.00 58.59  ? 62  PHE R CZ  1 
ATOM 352  N N   . THR A 1 63  ? 129.261 129.273 139.722 1.00 54.30  ? 63  THR R N   1 
ATOM 353  C CA  . THR A 1 63  ? 129.836 130.478 139.131 1.00 54.30  ? 63  THR R CA  1 
ATOM 354  C C   . THR A 1 63  ? 130.224 130.325 137.665 1.00 54.30  ? 63  THR R C   1 
ATOM 355  O O   . THR A 1 63  ? 130.684 131.302 137.065 1.00 54.30  ? 63  THR R O   1 
ATOM 356  C CB  . THR A 1 63  ? 131.070 130.908 139.926 1.00 54.30  ? 63  THR R CB  1 
ATOM 357  O OG1 . THR A 1 63  ? 131.407 132.261 139.594 1.00 54.30  ? 63  THR R OG1 1 
ATOM 358  C CG2 . THR A 1 63  ? 132.248 130.002 139.594 1.00 54.30  ? 63  THR R CG2 1 
ATOM 359  N N   . GLY A 1 64  ? 130.050 129.147 137.071 1.00 58.86  ? 64  GLY R N   1 
ATOM 360  C CA  . GLY A 1 64  ? 130.386 128.962 135.673 1.00 58.86  ? 64  GLY R CA  1 
ATOM 361  C C   . GLY A 1 64  ? 129.411 129.645 134.734 1.00 58.86  ? 64  GLY R C   1 
ATOM 362  O O   . GLY A 1 64  ? 128.892 129.021 133.803 1.00 58.86  ? 64  GLY R O   1 
ATOM 363  N N   . PHE A 1 65  ? 129.147 130.931 134.983 1.00 58.63  ? 65  PHE R N   1 
ATOM 364  C CA  . PHE A 1 65  ? 128.247 131.698 134.128 1.00 58.63  ? 65  PHE R CA  1 
ATOM 365  C C   . PHE A 1 65  ? 128.799 131.810 132.712 1.00 58.63  ? 65  PHE R C   1 
ATOM 366  O O   . PHE A 1 65  ? 128.111 131.495 131.734 1.00 58.63  ? 65  PHE R O   1 
ATOM 367  C CB  . PHE A 1 65  ? 128.029 133.089 134.726 1.00 58.63  ? 65  PHE R CB  1 
ATOM 368  C CG  . PHE A 1 65  ? 127.345 133.077 136.061 1.00 58.63  ? 65  PHE R CG  1 
ATOM 369  C CD1 . PHE A 1 65  ? 125.967 132.989 136.147 1.00 58.63  ? 65  PHE R CD1 1 
ATOM 370  C CD2 . PHE A 1 65  ? 128.082 133.148 137.232 1.00 58.63  ? 65  PHE R CD2 1 
ATOM 371  C CE1 . PHE A 1 65  ? 125.336 132.980 137.374 1.00 58.63  ? 65  PHE R CE1 1 
ATOM 372  C CE2 . PHE A 1 65  ? 127.456 133.137 138.463 1.00 58.63  ? 65  PHE R CE2 1 
ATOM 373  C CZ  . PHE A 1 65  ? 126.082 133.051 138.535 1.00 58.63  ? 65  PHE R CZ  1 
ATOM 374  N N   . LYS A 1 66  ? 130.044 132.264 132.588 1.00 57.40  ? 66  LYS R N   1 
ATOM 375  C CA  . LYS A 1 66  ? 130.736 132.340 131.306 1.00 57.40  ? 66  LYS R CA  1 
ATOM 376  C C   . LYS A 1 66  ? 132.176 131.909 131.524 1.00 57.40  ? 66  LYS R C   1 
ATOM 377  O O   . LYS A 1 66  ? 132.834 132.391 132.451 1.00 57.40  ? 66  LYS R O   1 
ATOM 378  C CB  . LYS A 1 66  ? 130.689 133.752 130.705 1.00 57.40  ? 66  LYS R CB  1 
ATOM 379  C CG  . LYS A 1 66  ? 129.330 134.442 130.734 1.00 57.40  ? 66  LYS R CG  1 
ATOM 380  C CD  . LYS A 1 66  ? 129.150 135.298 131.979 1.00 57.40  ? 66  LYS R CD  1 
ATOM 381  C CE  . LYS A 1 66  ? 127.778 135.952 131.996 1.00 57.40  ? 66  LYS R CE  1 
ATOM 382  N NZ  . LYS A 1 66  ? 127.508 136.658 133.279 1.00 57.40  ? 66  LYS R NZ  1 
ATOM 383  N N   . TRP A 1 67  ? 132.660 131.001 130.680 1.00 61.98  ? 67  TRP R N   1 
ATOM 384  C CA  . TRP A 1 67  ? 134.044 130.562 130.780 1.00 61.98  ? 67  TRP R CA  1 
ATOM 385  C C   . TRP A 1 67  ? 134.989 131.715 130.466 1.00 61.98  ? 67  TRP R C   1 
ATOM 386  O O   . TRP A 1 67  ? 134.832 132.410 129.458 1.00 61.98  ? 67  TRP R O   1 
ATOM 387  C CB  . TRP A 1 67  ? 134.301 129.393 129.828 1.00 61.98  ? 67  TRP R CB  1 
ATOM 388  N N   . LYS A 1 68  ? 135.977 131.911 131.341 1.00 56.13  ? 68  LYS R N   1 
ATOM 389  C CA  . LYS A 1 68  ? 136.956 132.992 131.220 1.00 56.13  ? 68  LYS R CA  1 
ATOM 390  C C   . LYS A 1 68  ? 136.258 134.348 131.087 1.00 56.13  ? 68  LYS R C   1 
ATOM 391  O O   . LYS A 1 68  ? 136.492 135.114 130.151 1.00 56.13  ? 68  LYS R O   1 
ATOM 392  C CB  . LYS A 1 68  ? 137.909 132.739 130.047 1.00 56.13  ? 68  LYS R CB  1 
ATOM 393  N N   . LYS A 1 69  ? 135.391 134.631 132.055 1.00 42.46  ? 69  LYS R N   1 
ATOM 394  C CA  . LYS A 1 69  ? 134.621 135.863 132.051 1.00 42.46  ? 69  LYS R CA  1 
ATOM 395  C C   . LYS A 1 69  ? 135.518 136.988 132.586 1.00 42.46  ? 69  LYS R C   1 
ATOM 396  O O   . LYS A 1 69  ? 136.647 136.754 133.026 1.00 42.46  ? 69  LYS R O   1 
ATOM 397  C CB  . LYS A 1 69  ? 133.328 135.644 132.848 1.00 42.46  ? 69  LYS R CB  1 
ATOM 398  C CG  . LYS A 1 69  ? 132.517 136.861 133.286 1.00 42.46  ? 69  LYS R CG  1 
ATOM 399  C CD  . LYS A 1 69  ? 132.000 137.649 132.088 1.00 42.46  ? 69  LYS R CD  1 
ATOM 400  C CE  . LYS A 1 69  ? 131.431 138.993 132.511 1.00 42.46  ? 69  LYS R CE  1 
ATOM 401  N NZ  . LYS A 1 69  ? 130.341 138.852 133.514 1.00 42.46  ? 69  LYS R NZ  1 
ATOM 402  N N   . THR A 1 70  ? 135.026 138.222 132.552 1.00 34.04  ? 70  THR R N   1 
ATOM 403  C CA  . THR A 1 70  ? 135.838 139.393 132.860 1.00 34.04  ? 70  THR R CA  1 
ATOM 404  C C   . THR A 1 70  ? 136.129 139.462 134.361 1.00 34.04  ? 70  THR R C   1 
ATOM 405  O O   . THR A 1 70  ? 135.854 138.535 135.128 1.00 34.04  ? 70  THR R O   1 
ATOM 406  C CB  . THR A 1 70  ? 135.149 140.660 132.364 1.00 34.04  ? 70  THR R CB  1 
ATOM 407  O OG1 . THR A 1 70  ? 133.944 140.873 133.109 1.00 34.04  ? 70  THR R OG1 1 
ATOM 408  C CG2 . THR A 1 70  ? 134.811 140.540 130.885 1.00 34.04  ? 70  THR R CG2 1 
ATOM 409  N N   . VAL A 1 71  ? 136.700 140.592 134.786 1.00 27.47  ? 71  VAL R N   1 
ATOM 410  C CA  . VAL A 1 71  ? 137.312 140.703 136.108 1.00 27.47  ? 71  VAL R CA  1 
ATOM 411  C C   . VAL A 1 71  ? 136.302 140.499 137.232 1.00 27.47  ? 71  VAL R C   1 
ATOM 412  O O   . VAL A 1 71  ? 136.673 140.069 138.330 1.00 27.47  ? 71  VAL R O   1 
ATOM 413  C CB  . VAL A 1 71  ? 138.028 142.062 136.235 1.00 27.47  ? 71  VAL R CB  1 
ATOM 414  C CG1 . VAL A 1 71  ? 139.058 142.215 135.131 1.00 27.47  ? 71  VAL R CG1 1 
ATOM 415  C CG2 . VAL A 1 71  ? 137.027 143.203 136.187 1.00 27.47  ? 71  VAL R CG2 1 
ATOM 416  N N   . THR A 1 72  ? 135.022 140.806 136.992 1.00 29.06  ? 72  THR R N   1 
ATOM 417  C CA  . THR A 1 72  ? 134.032 140.726 138.064 1.00 29.06  ? 72  THR R CA  1 
ATOM 418  C C   . THR A 1 72  ? 133.889 139.301 138.587 1.00 29.06  ? 72  THR R C   1 
ATOM 419  O O   . THR A 1 72  ? 133.813 139.080 139.804 1.00 29.06  ? 72  THR R O   1 
ATOM 420  C CB  . THR A 1 72  ? 132.682 141.257 137.579 1.00 29.06  ? 72  THR R CB  1 
ATOM 421  O OG1 . THR A 1 72  ? 132.004 140.239 136.832 1.00 29.06  ? 72  THR R OG1 1 
ATOM 422  C CG2 . THR A 1 72  ? 132.875 142.485 136.700 1.00 29.06  ? 72  THR R CG2 1 
ATOM 423  N N   . THR A 1 73  ? 133.854 138.319 137.684 1.00 29.07  ? 73  THR R N   1 
ATOM 424  C CA  . THR A 1 73  ? 133.781 136.927 138.113 1.00 29.07  ? 73  THR R CA  1 
ATOM 425  C C   . THR A 1 73  ? 135.037 136.517 138.872 1.00 29.07  ? 73  THR R C   1 
ATOM 426  O O   . THR A 1 73  ? 134.964 135.733 139.822 1.00 29.07  ? 73  THR R O   1 
ATOM 427  C CB  . THR A 1 73  ? 133.546 136.015 136.908 1.00 29.07  ? 73  THR R CB  1 
ATOM 428  O OG1 . THR A 1 73  ? 132.287 136.340 136.309 1.00 29.07  ? 73  THR R OG1 1 
ATOM 429  C CG2 . THR A 1 73  ? 133.533 134.551 137.328 1.00 29.07  ? 73  THR R CG2 1 
ATOM 430  N N   . LEU A 1 74  ? 136.200 137.035 138.470 1.00 25.86  ? 74  LEU R N   1 
ATOM 431  C CA  . LEU A 1 74  ? 137.425 136.738 139.209 1.00 25.86  ? 74  LEU R CA  1 
ATOM 432  C C   . LEU A 1 74  ? 137.364 137.296 140.627 1.00 25.86  ? 74  LEU R C   1 
ATOM 433  O O   . LEU A 1 74  ? 137.743 136.611 141.588 1.00 25.86  ? 74  LEU R O   1 
ATOM 434  C CB  . LEU A 1 74  ? 138.638 137.291 138.460 1.00 25.86  ? 74  LEU R CB  1 
ATOM 435  C CG  . LEU A 1 74  ? 138.933 136.673 137.091 1.00 25.86  ? 74  LEU R CG  1 
ATOM 436  C CD1 . LEU A 1 74  ? 140.378 136.920 136.692 1.00 25.86  ? 74  LEU R CD1 1 
ATOM 437  C CD2 . LEU A 1 74  ? 138.621 135.182 137.081 1.00 25.86  ? 74  LEU R CD2 1 
ATOM 438  N N   . TRP A 1 75  ? 136.881 138.534 140.777 1.00 29.88  ? 75  TRP R N   1 
ATOM 439  C CA  . TRP A 1 75  ? 136.699 139.106 142.108 1.00 29.88  ? 75  TRP R CA  1 
ATOM 440  C C   . TRP A 1 75  ? 135.756 138.251 142.941 1.00 29.88  ? 75  TRP R C   1 
ATOM 441  O O   . TRP A 1 75  ? 136.029 137.956 144.112 1.00 29.88  ? 75  TRP R O   1 
ATOM 442  C CB  . TRP A 1 75  ? 136.148 140.531 142.013 1.00 29.88  ? 75  TRP R CB  1 
ATOM 443  C CG  . TRP A 1 75  ? 136.916 141.500 141.163 1.00 29.88  ? 75  TRP R CG  1 
ATOM 444  C CD1 . TRP A 1 75  ? 136.413 142.286 140.167 1.00 29.88  ? 75  TRP R CD1 1 
ATOM 445  C CD2 . TRP A 1 75  ? 138.307 141.830 141.267 1.00 29.88  ? 75  TRP R CD2 1 
ATOM 446  N NE1 . TRP A 1 75  ? 137.407 143.061 139.625 1.00 29.88  ? 75  TRP R NE1 1 
ATOM 447  C CE2 . TRP A 1 75  ? 138.579 142.803 140.285 1.00 29.88  ? 75  TRP R CE2 1 
ATOM 448  C CE3 . TRP A 1 75  ? 139.350 141.390 142.086 1.00 29.88  ? 75  TRP R CE3 1 
ATOM 449  C CZ2 . TRP A 1 75  ? 139.849 143.342 140.099 1.00 29.88  ? 75  TRP R CZ2 1 
ATOM 450  C CZ3 . TRP A 1 75  ? 140.609 141.928 141.900 1.00 29.88  ? 75  TRP R CZ3 1 
ATOM 451  C CH2 . TRP A 1 75  ? 140.848 142.892 140.915 1.00 29.88  ? 75  TRP R CH2 1 
ATOM 452  N N   . PHE A 1 76  ? 134.625 137.857 142.350 1.00 24.08  ? 76  PHE R N   1 
ATOM 453  C CA  . PHE A 1 76  ? 133.637 137.075 143.085 1.00 24.08  ? 76  PHE R CA  1 
ATOM 454  C C   . PHE A 1 76  ? 134.198 135.719 143.493 1.00 24.08  ? 76  PHE R C   1 
ATOM 455  O O   . PHE A 1 76  ? 133.971 135.260 144.617 1.00 24.08  ? 76  PHE R O   1 
ATOM 456  C CB  . PHE A 1 76  ? 132.371 136.911 142.246 1.00 24.08  ? 76  PHE R CB  1 
ATOM 457  C CG  . PHE A 1 76  ? 131.571 138.176 142.103 1.00 24.08  ? 76  PHE R CG  1 
ATOM 458  C CD1 . PHE A 1 76  ? 131.847 139.278 142.896 1.00 24.08  ? 76  PHE R CD1 1 
ATOM 459  C CD2 . PHE A 1 76  ? 130.549 138.265 141.175 1.00 24.08  ? 76  PHE R CD2 1 
ATOM 460  C CE1 . PHE A 1 76  ? 131.118 140.443 142.767 1.00 24.08  ? 76  PHE R CE1 1 
ATOM 461  C CE2 . PHE A 1 76  ? 129.815 139.428 141.042 1.00 24.08  ? 76  PHE R CE2 1 
ATOM 462  C CZ  . PHE A 1 76  ? 130.100 140.518 141.840 1.00 24.08  ? 76  PHE R CZ  1 
ATOM 463  N N   . LEU A 1 77  ? 134.939 135.068 142.594 1.00 30.81  ? 77  LEU R N   1 
ATOM 464  C CA  . LEU A 1 77  ? 135.541 133.777 142.909 1.00 30.81  ? 77  LEU R CA  1 
ATOM 465  C C   . LEU A 1 77  ? 136.554 133.902 144.038 1.00 30.81  ? 77  LEU R C   1 
ATOM 466  O O   . LEU A 1 77  ? 136.580 133.073 144.955 1.00 30.81  ? 77  LEU R O   1 
ATOM 467  C CB  . LEU A 1 77  ? 136.197 133.186 141.661 1.00 30.81  ? 77  LEU R CB  1 
ATOM 468  C CG  . LEU A 1 77  ? 135.334 132.241 140.826 1.00 30.81  ? 77  LEU R CG  1 
ATOM 469  C CD1 . LEU A 1 77  ? 135.997 131.944 139.492 1.00 30.81  ? 77  LEU R CD1 1 
ATOM 470  C CD2 . LEU A 1 77  ? 135.086 130.957 141.598 1.00 30.81  ? 77  LEU R CD2 1 
ATOM 471  N N   . ASN A 1 78  ? 137.402 134.932 143.988 1.00 26.16  ? 78  ASN R N   1 
ATOM 472  C CA  . ASN A 1 78  ? 138.392 135.108 145.047 1.00 26.16  ? 78  ASN R CA  1 
ATOM 473  C C   . ASN A 1 78  ? 137.725 135.384 146.390 1.00 26.16  ? 78  ASN R C   1 
ATOM 474  O O   . ASN A 1 78  ? 138.111 134.801 147.414 1.00 26.16  ? 78  ASN R O   1 
ATOM 475  C CB  . ASN A 1 78  ? 139.354 136.234 144.678 1.00 26.16  ? 78  ASN R CB  1 
ATOM 476  C CG  . ASN A 1 78  ? 140.309 135.842 143.569 1.00 26.16  ? 78  ASN R CG  1 
ATOM 477  O OD1 . ASN A 1 78  ? 140.345 134.687 143.146 1.00 26.16  ? 78  ASN R OD1 1 
ATOM 478  N ND2 . ASN A 1 78  ? 141.090 136.803 143.093 1.00 26.16  ? 78  ASN R ND2 1 
ATOM 479  N N   . LEU A 1 79  ? 136.714 136.257 146.403 1.00 28.51  ? 79  LEU R N   1 
ATOM 480  C CA  . LEU A 1 79  ? 136.006 136.548 147.646 1.00 28.51  ? 79  LEU R CA  1 
ATOM 481  C C   . LEU A 1 79  ? 135.317 135.305 148.192 1.00 28.51  ? 79  LEU R C   1 
ATOM 482  O O   . LEU A 1 79  ? 135.368 135.035 149.399 1.00 28.51  ? 79  LEU R O   1 
ATOM 483  C CB  . LEU A 1 79  ? 134.989 137.667 147.418 1.00 28.51  ? 79  LEU R CB  1 
ATOM 484  C CG  . LEU A 1 79  ? 133.987 137.922 148.546 1.00 28.51  ? 79  LEU R CG  1 
ATOM 485  C CD1 . LEU A 1 79  ? 134.698 138.368 149.815 1.00 28.51  ? 79  LEU R CD1 1 
ATOM 486  C CD2 . LEU A 1 79  ? 132.943 138.942 148.118 1.00 28.51  ? 79  LEU R CD2 1 
ATOM 487  N N   . ALA A 1 80  ? 134.672 134.531 147.315 1.00 31.64  ? 80  ALA R N   1 
ATOM 488  C CA  . ALA A 1 80  ? 133.981 133.325 147.752 1.00 31.64  ? 80  ALA R CA  1 
ATOM 489  C C   . ALA A 1 80  ? 134.958 132.289 148.289 1.00 31.64  ? 80  ALA R C   1 
ATOM 490  O O   . ALA A 1 80  ? 134.667 131.620 149.283 1.00 31.64  ? 80  ALA R O   1 
ATOM 491  C CB  . ALA A 1 80  ? 133.157 132.748 146.603 1.00 31.64  ? 80  ALA R CB  1 
ATOM 492  N N   . ILE A 1 81  ? 136.121 132.141 147.650 1.00 32.08  ? 81  ILE R N   1 
ATOM 493  C CA  . ILE A 1 81  ? 137.118 131.190 148.137 1.00 32.08  ? 81  ILE R CA  1 
ATOM 494  C C   . ILE A 1 81  ? 137.634 131.609 149.508 1.00 32.08  ? 81  ILE R C   1 
ATOM 495  O O   . ILE A 1 81  ? 137.761 130.781 150.422 1.00 32.08  ? 81  ILE R O   1 
ATOM 496  C CB  . ILE A 1 81  ? 138.264 131.046 147.117 1.00 32.08  ? 81  ILE R CB  1 
ATOM 497  C CG1 . ILE A 1 81  ? 137.803 130.230 145.908 1.00 32.08  ? 81  ILE R CG1 1 
ATOM 498  C CG2 . ILE A 1 81  ? 139.484 130.405 147.763 1.00 32.08  ? 81  ILE R CG2 1 
ATOM 499  C CD1 . ILE A 1 81  ? 138.773 130.257 144.748 1.00 32.08  ? 81  ILE R CD1 1 
ATOM 500  N N   . ALA A 1 82  ? 137.939 132.900 149.675 1.00 31.76  ? 82  ALA R N   1 
ATOM 501  C CA  . ALA A 1 82  ? 138.420 133.377 150.968 1.00 31.76  ? 82  ALA R CA  1 
ATOM 502  C C   . ALA A 1 82  ? 137.376 133.153 152.056 1.00 31.76  ? 82  ALA R C   1 
ATOM 503  O O   . ALA A 1 82  ? 137.692 132.658 153.146 1.00 31.76  ? 82  ALA R O   1 
ATOM 504  C CB  . ALA A 1 82  ? 138.797 134.856 150.875 1.00 31.76  ? 82  ALA R CB  1 
ATOM 505  N N   . ASP A 1 83  ? 136.117 133.491 151.765 1.00 33.58  ? 83  ASP R N   1 
ATOM 506  C CA  . ASP A 1 83  ? 135.054 133.300 152.746 1.00 33.58  ? 83  ASP R CA  1 
ATOM 507  C C   . ASP A 1 83  ? 134.839 131.822 153.051 1.00 33.58  ? 83  ASP R C   1 
ATOM 508  O O   . ASP A 1 83  ? 134.586 131.453 154.202 1.00 33.58  ? 83  ASP R O   1 
ATOM 509  C CB  . ASP A 1 83  ? 133.759 133.939 152.247 1.00 33.58  ? 83  ASP R CB  1 
ATOM 510  C CG  . ASP A 1 83  ? 132.615 133.780 153.228 1.00 33.58  ? 83  ASP R CG  1 
ATOM 511  O OD1 . ASP A 1 83  ? 132.858 133.890 154.448 1.00 33.58  ? 83  ASP R OD1 1 
ATOM 512  O OD2 . ASP A 1 83  ? 131.473 133.547 152.780 1.00 33.58  ? 83  ASP R OD2 1 
ATOM 513  N N   . PHE A 1 84  ? 134.935 130.964 152.034 1.00 36.89  ? 84  PHE R N   1 
ATOM 514  C CA  . PHE A 1 84  ? 134.747 129.533 152.240 1.00 36.89  ? 84  PHE R CA  1 
ATOM 515  C C   . PHE A 1 84  ? 135.829 128.960 153.144 1.00 36.89  ? 84  PHE R C   1 
ATOM 516  O O   . PHE A 1 84  ? 135.531 128.191 154.065 1.00 36.89  ? 84  PHE R O   1 
ATOM 517  C CB  . PHE A 1 84  ? 134.728 128.819 150.887 1.00 36.89  ? 84  PHE R CB  1 
ATOM 518  C CG  . PHE A 1 84  ? 134.227 127.404 150.948 1.00 36.89  ? 84  PHE R CG  1 
ATOM 519  C CD1 . PHE A 1 84  ? 132.870 127.134 150.951 1.00 36.89  ? 84  PHE R CD1 1 
ATOM 520  C CD2 . PHE A 1 84  ? 135.114 126.342 150.967 1.00 36.89  ? 84  PHE R CD2 1 
ATOM 521  C CE1 . PHE A 1 84  ? 132.406 125.834 150.997 1.00 36.89  ? 84  PHE R CE1 1 
ATOM 522  C CE2 . PHE A 1 84  ? 134.656 125.038 151.013 1.00 36.89  ? 84  PHE R CE2 1 
ATOM 523  C CZ  . PHE A 1 84  ? 133.300 124.785 151.028 1.00 36.89  ? 84  PHE R CZ  1 
ATOM 524  N N   . ILE A 1 85  ? 137.090 129.332 152.906 1.00 34.20  ? 85  ILE R N   1 
ATOM 525  C CA  . ILE A 1 85  ? 138.171 128.857 153.768 1.00 34.20  ? 85  ILE R CA  1 
ATOM 526  C C   . ILE A 1 85  ? 137.994 129.386 155.187 1.00 34.20  ? 85  ILE R C   1 
ATOM 527  O O   . ILE A 1 85  ? 138.155 128.647 156.171 1.00 34.20  ? 85  ILE R O   1 
ATOM 528  C CB  . ILE A 1 85  ? 139.540 129.247 153.181 1.00 34.20  ? 85  ILE R CB  1 
ATOM 529  C CG1 . ILE A 1 85  ? 139.697 128.678 151.769 1.00 34.20  ? 85  ILE R CG1 1 
ATOM 530  C CG2 . ILE A 1 85  ? 140.664 128.749 154.074 1.00 34.20  ? 85  ILE R CG2 1 
ATOM 531  C CD1 . ILE A 1 85  ? 139.699 127.166 151.716 1.00 34.20  ? 85  ILE R CD1 1 
ATOM 532  N N   . PHE A 1 86  ? 137.644 130.670 155.313 1.00 33.60  ? 86  PHE R N   1 
ATOM 533  C CA  . PHE A 1 86  ? 137.455 131.269 156.630 1.00 33.60  ? 86  PHE R CA  1 
ATOM 534  C C   . PHE A 1 86  ? 136.347 130.562 157.403 1.00 33.60  ? 86  PHE R C   1 
ATOM 535  O O   . PHE A 1 86  ? 136.503 130.254 158.590 1.00 33.60  ? 86  PHE R O   1 
ATOM 536  C CB  . PHE A 1 86  ? 137.148 132.758 156.460 1.00 33.60  ? 86  PHE R CB  1 
ATOM 537  C CG  . PHE A 1 86  ? 137.498 133.602 157.651 1.00 33.60  ? 86  PHE R CG  1 
ATOM 538  C CD1 . PHE A 1 86  ? 138.744 133.507 158.246 1.00 33.60  ? 86  PHE R CD1 1 
ATOM 539  C CD2 . PHE A 1 86  ? 136.597 134.531 158.143 1.00 33.60  ? 86  PHE R CD2 1 
ATOM 540  C CE1 . PHE A 1 86  ? 139.070 134.296 159.333 1.00 33.60  ? 86  PHE R CE1 1 
ATOM 541  C CE2 . PHE A 1 86  ? 136.920 135.327 159.224 1.00 33.60  ? 86  PHE R CE2 1 
ATOM 542  C CZ  . PHE A 1 86  ? 138.156 135.207 159.822 1.00 33.60  ? 86  PHE R CZ  1 
ATOM 543  N N   . LEU A 1 87  ? 135.235 130.258 156.736 1.00 34.30  ? 87  LEU R N   1 
ATOM 544  C CA  . LEU A 1 87  ? 134.113 129.613 157.404 1.00 34.30  ? 87  LEU R CA  1 
ATOM 545  C C   . LEU A 1 87  ? 134.333 128.125 157.649 1.00 34.30  ? 87  LEU R C   1 
ATOM 546  O O   . LEU A 1 87  ? 133.732 127.578 158.579 1.00 34.30  ? 87  LEU R O   1 
ATOM 547  C CB  . LEU A 1 87  ? 132.830 129.831 156.600 1.00 34.30  ? 87  LEU R CB  1 
ATOM 548  C CG  . LEU A 1 87  ? 132.354 131.285 156.539 1.00 34.30  ? 87  LEU R CG  1 
ATOM 549  C CD1 . LEU A 1 87  ? 130.891 131.361 156.152 1.00 34.30  ? 87  LEU R CD1 1 
ATOM 550  C CD2 . LEU A 1 87  ? 132.592 131.995 157.866 1.00 34.30  ? 87  LEU R CD2 1 
ATOM 551  N N   . LEU A 1 88  ? 135.159 127.450 156.843 1.00 36.33  ? 88  LEU R N   1 
ATOM 552  C CA  . LEU A 1 88  ? 135.465 126.055 157.141 1.00 36.33  ? 88  LEU R CA  1 
ATOM 553  C C   . LEU A 1 88  ? 136.520 125.916 158.229 1.00 36.33  ? 88  LEU R C   1 
ATOM 554  O O   . LEU A 1 88  ? 136.625 124.846 158.837 1.00 36.33  ? 88  LEU R O   1 
ATOM 555  C CB  . LEU A 1 88  ? 135.908 125.303 155.879 1.00 36.33  ? 88  LEU R CB  1 
ATOM 556  C CG  . LEU A 1 88  ? 137.155 125.690 155.077 1.00 36.33  ? 88  LEU R CG  1 
ATOM 557  C CD1 . LEU A 1 88  ? 138.423 125.098 155.663 1.00 36.33  ? 88  LEU R CD1 1 
ATOM 558  C CD2 . LEU A 1 88  ? 137.005 125.256 153.633 1.00 36.33  ? 88  LEU R CD2 1 
ATOM 559  N N   . PHE A 1 89  ? 137.313 126.960 158.475 1.00 37.04  ? 89  PHE R N   1 
ATOM 560  C CA  . PHE A 1 89  ? 138.181 126.994 159.647 1.00 37.04  ? 89  PHE R CA  1 
ATOM 561  C C   . PHE A 1 89  ? 137.519 127.630 160.865 1.00 37.04  ? 89  PHE R C   1 
ATOM 562  O O   . PHE A 1 89  ? 138.079 127.559 161.963 1.00 37.04  ? 89  PHE R O   1 
ATOM 563  C CB  . PHE A 1 89  ? 139.484 127.724 159.310 1.00 37.04  ? 89  PHE R CB  1 
ATOM 564  C CG  . PHE A 1 89  ? 140.445 126.894 158.506 1.00 37.04  ? 89  PHE R CG  1 
ATOM 565  C CD1 . PHE A 1 89  ? 140.335 125.514 158.486 1.00 37.04  ? 89  PHE R CD1 1 
ATOM 566  C CD2 . PHE A 1 89  ? 141.428 127.492 157.740 1.00 37.04  ? 89  PHE R CD2 1 
ATOM 567  C CE1 . PHE A 1 89  ? 141.212 124.744 157.745 1.00 37.04  ? 89  PHE R CE1 1 
ATOM 568  C CE2 . PHE A 1 89  ? 142.307 126.729 156.994 1.00 37.04  ? 89  PHE R CE2 1 
ATOM 569  C CZ  . PHE A 1 89  ? 142.197 125.353 156.995 1.00 37.04  ? 89  PHE R CZ  1 
ATOM 570  N N   . LEU A 1 90  ? 136.354 128.248 160.689 1.00 36.13  ? 90  LEU R N   1 
ATOM 571  C CA  . LEU A 1 90  ? 135.546 128.693 161.824 1.00 36.13  ? 90  LEU R CA  1 
ATOM 572  C C   . LEU A 1 90  ? 135.188 127.593 162.825 1.00 36.13  ? 90  LEU R C   1 
ATOM 573  O O   . LEU A 1 90  ? 135.226 127.873 164.036 1.00 36.13  ? 90  LEU R O   1 
ATOM 574  C CB  . LEU A 1 90  ? 134.271 129.369 161.297 1.00 36.13  ? 90  LEU R CB  1 
ATOM 575  C CG  . LEU A 1 90  ? 133.145 129.643 162.295 1.00 36.13  ? 90  LEU R CG  1 
ATOM 576  C CD1 . LEU A 1 90  ? 133.591 130.636 163.354 1.00 36.13  ? 90  LEU R CD1 1 
ATOM 577  C CD2 . LEU A 1 90  ? 131.902 130.144 161.576 1.00 36.13  ? 90  LEU R CD2 1 
ATOM 578  N N   . PRO A 1 91  ? 134.815 126.368 162.422 1.00 36.38  ? 91  PRO R N   1 
ATOM 579  C CA  . PRO A 1 91  ? 134.448 125.359 163.434 1.00 36.38  ? 91  PRO R CA  1 
ATOM 580  C C   . PRO A 1 91  ? 135.541 125.076 164.448 1.00 36.38  ? 91  PRO R C   1 
ATOM 581  O O   . PRO A 1 91  ? 135.228 124.741 165.597 1.00 36.38  ? 91  PRO R O   1 
ATOM 582  C CB  . PRO A 1 91  ? 134.118 124.118 162.592 1.00 36.38  ? 91  PRO R CB  1 
ATOM 583  C CG  . PRO A 1 91  ? 133.732 124.658 161.273 1.00 36.38  ? 91  PRO R CG  1 
ATOM 584  C CD  . PRO A 1 91  ? 134.607 125.849 161.058 1.00 36.38  ? 91  PRO R CD  1 
ATOM 585  N N   . LEU A 1 92  ? 136.813 125.210 164.074 1.00 37.94  ? 92  LEU R N   1 
ATOM 586  C CA  . LEU A 1 92  ? 137.873 125.101 165.070 1.00 37.94  ? 92  LEU R CA  1 
ATOM 587  C C   . LEU A 1 92  ? 137.719 126.174 166.142 1.00 37.94  ? 92  LEU R C   1 
ATOM 588  O O   . LEU A 1 92  ? 137.847 125.893 167.341 1.00 37.94  ? 92  LEU R O   1 
ATOM 589  C CB  . LEU A 1 92  ? 139.240 125.202 164.393 1.00 37.94  ? 92  LEU R CB  1 
ATOM 590  C CG  . LEU A 1 92  ? 140.438 124.657 165.169 1.00 37.94  ? 92  LEU R CG  1 
ATOM 591  C CD1 . LEU A 1 92  ? 140.244 123.181 165.471 1.00 37.94  ? 92  LEU R CD1 1 
ATOM 592  C CD2 . LEU A 1 92  ? 141.723 124.881 164.389 1.00 37.94  ? 92  LEU R CD2 1 
ATOM 593  N N   . TYR A 1 93  ? 137.415 127.407 165.729 1.00 38.18  ? 93  TYR R N   1 
ATOM 594  C CA  . TYR A 1 93  ? 137.231 128.487 166.692 1.00 38.18  ? 93  TYR R CA  1 
ATOM 595  C C   . TYR A 1 93  ? 135.987 128.272 167.546 1.00 38.18  ? 93  TYR R C   1 
ATOM 596  O O   . TYR A 1 93  ? 136.000 128.568 168.747 1.00 38.18  ? 93  TYR R O   1 
ATOM 597  C CB  . TYR A 1 93  ? 137.161 129.832 165.971 1.00 38.18  ? 93  TYR R CB  1 
ATOM 598  C CG  . TYR A 1 93  ? 137.243 131.019 166.903 1.00 38.18  ? 93  TYR R CG  1 
ATOM 599  C CD1 . TYR A 1 93  ? 138.255 131.114 167.848 1.00 38.18  ? 93  TYR R CD1 1 
ATOM 600  C CD2 . TYR A 1 93  ? 136.310 132.045 166.838 1.00 38.18  ? 93  TYR R CD2 1 
ATOM 601  C CE1 . TYR A 1 93  ? 138.336 132.195 168.703 1.00 38.18  ? 93  TYR R CE1 1 
ATOM 602  C CE2 . TYR A 1 93  ? 136.383 133.132 167.689 1.00 38.18  ? 93  TYR R CE2 1 
ATOM 603  C CZ  . TYR A 1 93  ? 137.398 133.201 168.620 1.00 38.18  ? 93  TYR R CZ  1 
ATOM 604  O OH  . TYR A 1 93  ? 137.475 134.281 169.469 1.00 38.18  ? 93  TYR R OH  1 
ATOM 605  N N   . ILE A 1 94  ? 134.897 127.778 166.951 1.00 39.55  ? 94  ILE R N   1 
ATOM 606  C CA  . ILE A 1 94  ? 133.702 127.545 167.762 1.00 39.55  ? 94  ILE R CA  1 
ATOM 607  C C   . ILE A 1 94  ? 133.945 126.415 168.757 1.00 39.55  ? 94  ILE R C   1 
ATOM 608  O O   . ILE A 1 94  ? 133.438 126.457 169.884 1.00 39.55  ? 94  ILE R O   1 
ATOM 609  C CB  . ILE A 1 94  ? 132.453 127.281 166.895 1.00 39.55  ? 94  ILE R CB  1 
ATOM 610  C CG1 . ILE A 1 94  ? 131.191 127.392 167.752 1.00 39.55  ? 94  ILE R CG1 1 
ATOM 611  C CG2 . ILE A 1 94  ? 132.472 125.905 166.278 1.00 39.55  ? 94  ILE R CG2 1 
ATOM 612  C CD1 . ILE A 1 94  ? 129.907 127.363 166.958 1.00 39.55  ? 94  ILE R CD1 1 
ATOM 613  N N   . SER A 1 95  ? 134.720 125.396 168.374 1.00 38.50  ? 95  SER R N   1 
ATOM 614  C CA  . SER A 1 95  ? 135.076 124.346 169.321 1.00 38.50  ? 95  SER R CA  1 
ATOM 615  C C   . SER A 1 95  ? 135.946 124.894 170.444 1.00 38.50  ? 95  SER R C   1 
ATOM 616  O O   . SER A 1 95  ? 135.780 124.517 171.610 1.00 38.50  ? 95  SER R O   1 
ATOM 617  C CB  . SER A 1 95  ? 135.788 123.204 168.596 1.00 38.50  ? 95  SER R CB  1 
ATOM 618  O OG  . SER A 1 95  ? 137.174 123.469 168.467 1.00 38.50  ? 95  SER R OG  1 
ATOM 619  N N   . TYR A 1 96  ? 136.887 125.779 170.108 1.00 37.97  ? 96  TYR R N   1 
ATOM 620  C CA  . TYR A 1 96  ? 137.744 126.375 171.129 1.00 37.97  ? 96  TYR R CA  1 
ATOM 621  C C   . TYR A 1 96  ? 136.934 127.218 172.109 1.00 37.97  ? 96  TYR R C   1 
ATOM 622  O O   . TYR A 1 96  ? 137.154 127.162 173.324 1.00 37.97  ? 96  TYR R O   1 
ATOM 623  C CB  . TYR A 1 96  ? 138.838 127.213 170.465 1.00 37.97  ? 96  TYR R CB  1 
ATOM 624  C CG  . TYR A 1 96  ? 139.396 128.319 171.334 1.00 37.97  ? 96  TYR R CG  1 
ATOM 625  C CD1 . TYR A 1 96  ? 140.386 128.059 172.273 1.00 37.97  ? 96  TYR R CD1 1 
ATOM 626  C CD2 . TYR A 1 96  ? 138.949 129.628 171.201 1.00 37.97  ? 96  TYR R CD2 1 
ATOM 627  C CE1 . TYR A 1 96  ? 140.902 129.067 173.065 1.00 37.97  ? 96  TYR R CE1 1 
ATOM 628  C CE2 . TYR A 1 96  ? 139.459 130.641 171.988 1.00 37.97  ? 96  TYR R CE2 1 
ATOM 629  C CZ  . TYR A 1 96  ? 140.436 130.356 172.917 1.00 37.97  ? 96  TYR R CZ  1 
ATOM 630  O OH  . TYR A 1 96  ? 140.946 131.365 173.700 1.00 37.97  ? 96  TYR R OH  1 
ATOM 631  N N   . VAL A 1 97  ? 135.989 128.010 171.596 1.00 35.77  ? 97  VAL R N   1 
ATOM 632  C CA  . VAL A 1 97  ? 135.248 128.923 172.464 1.00 35.77  ? 97  VAL R CA  1 
ATOM 633  C C   . VAL A 1 97  ? 134.165 128.184 173.244 1.00 35.77  ? 97  VAL R C   1 
ATOM 634  O O   . VAL A 1 97  ? 133.805 128.592 174.355 1.00 35.77  ? 97  VAL R O   1 
ATOM 635  C CB  . VAL A 1 97  ? 134.666 130.091 171.643 1.00 35.77  ? 97  VAL R CB  1 
ATOM 636  C CG1 . VAL A 1 97  ? 133.552 129.614 170.727 1.00 35.77  ? 97  VAL R CG1 1 
ATOM 637  C CG2 . VAL A 1 97  ? 134.172 131.200 172.561 1.00 35.77  ? 97  VAL R CG2 1 
ATOM 638  N N   . ALA A 1 98  ? 133.634 127.090 172.695 1.00 38.26  ? 98  ALA R N   1 
ATOM 639  C CA  . ALA A 1 98  ? 132.560 126.356 173.350 1.00 38.26  ? 98  ALA R CA  1 
ATOM 640  C C   . ALA A 1 98  ? 133.047 125.466 174.484 1.00 38.26  ? 98  ALA R C   1 
ATOM 641  O O   . ALA A 1 98  ? 132.220 124.966 175.254 1.00 38.26  ? 98  ALA R O   1 
ATOM 642  C CB  . ALA A 1 98  ? 131.803 125.508 172.325 1.00 38.26  ? 98  ALA R CB  1 
ATOM 643  N N   . MET A 1 99  ? 134.358 125.255 174.607 1.00 42.75  ? 99  MET R N   1 
ATOM 644  C CA  . MET A 1 99  ? 134.926 124.418 175.656 1.00 42.75  ? 99  MET R CA  1 
ATOM 645  C C   . MET A 1 99  ? 135.418 125.237 176.844 1.00 42.75  ? 99  MET R C   1 
ATOM 646  O O   . MET A 1 99  ? 136.404 124.862 177.488 1.00 42.75  ? 99  MET R O   1 
ATOM 647  C CB  . MET A 1 99  ? 136.060 123.560 175.096 1.00 42.75  ? 99  MET R CB  1 
ATOM 648  C CG  . MET A 1 99  ? 135.605 122.224 174.534 1.00 42.75  ? 99  MET R CG  1 
ATOM 649  S SD  . MET A 1 99  ? 136.867 121.434 173.518 1.00 42.75  ? 99  MET R SD  1 
ATOM 650  C CE  . MET A 1 99  ? 138.100 121.049 174.758 1.00 42.75  ? 99  MET R CE  1 
ATOM 651  N N   . ASN A 1 100 ? 134.746 126.352 177.141 1.00 45.59  ? 100 ASN R N   1 
ATOM 652  C CA  . ASN A 1 100 ? 135.119 127.240 178.242 1.00 45.59  ? 100 ASN R CA  1 
ATOM 653  C C   . ASN A 1 100 ? 136.552 127.747 178.080 1.00 45.59  ? 100 ASN R C   1 
ATOM 654  O O   . ASN A 1 100 ? 137.368 127.685 179.004 1.00 45.59  ? 100 ASN R O   1 
ATOM 655  C CB  . ASN A 1 100 ? 134.925 126.554 179.598 1.00 45.59  ? 100 ASN R CB  1 
ATOM 656  C CG  . ASN A 1 100 ? 133.498 126.092 179.817 1.00 45.59  ? 100 ASN R CG  1 
ATOM 657  O OD1 . ASN A 1 100 ? 132.580 126.523 179.119 1.00 45.59  ? 100 ASN R OD1 1 
ATOM 658  N ND2 . ASN A 1 100 ? 133.304 125.212 180.792 1.00 45.59  ? 100 ASN R ND2 1 
ATOM 659  N N   . PHE A 1 101 ? 136.852 128.248 176.880 1.00 45.06  ? 101 PHE R N   1 
ATOM 660  C CA  . PHE A 1 101 ? 138.138 128.881 176.577 1.00 45.06  ? 101 PHE R CA  1 
ATOM 661  C C   . PHE A 1 101 ? 139.302 127.913 176.778 1.00 45.06  ? 101 PHE R C   1 
ATOM 662  O O   . PHE A 1 101 ? 140.372 128.290 177.260 1.00 45.06  ? 101 PHE R O   1 
ATOM 663  C CB  . PHE A 1 101 ? 138.330 130.149 177.412 1.00 45.06  ? 101 PHE R CB  1 
ATOM 664  C CG  . PHE A 1 101 ? 137.392 131.264 177.046 1.00 45.06  ? 101 PHE R CG  1 
ATOM 665  C CD1 . PHE A 1 101 ? 136.677 131.228 175.859 1.00 45.06  ? 101 PHE R CD1 1 
ATOM 666  C CD2 . PHE A 1 101 ? 137.201 132.335 177.902 1.00 45.06  ? 101 PHE R CD2 1 
ATOM 667  C CE1 . PHE A 1 101 ? 135.808 132.248 175.525 1.00 45.06  ? 101 PHE R CE1 1 
ATOM 668  C CE2 . PHE A 1 101 ? 136.329 133.354 177.575 1.00 45.06  ? 101 PHE R CE2 1 
ATOM 669  C CZ  . PHE A 1 101 ? 135.634 133.312 176.384 1.00 45.06  ? 101 PHE R CZ  1 
ATOM 670  N N   . HIS A 1 102 ? 139.092 126.655 176.404 1.00 44.21  ? 102 HIS R N   1 
ATOM 671  C CA  . HIS A 1 102 ? 140.110 125.616 176.501 1.00 44.21  ? 102 HIS R CA  1 
ATOM 672  C C   . HIS A 1 102 ? 140.551 125.212 175.101 1.00 44.21  ? 102 HIS R C   1 
ATOM 673  O O   . HIS A 1 102 ? 139.711 124.956 174.231 1.00 44.21  ? 102 HIS R O   1 
ATOM 674  C CB  . HIS A 1 102 ? 139.580 124.400 177.264 1.00 44.21  ? 102 HIS R CB  1 
ATOM 675  C CG  . HIS A 1 102 ? 140.612 123.344 177.514 1.00 44.21  ? 102 HIS R CG  1 
ATOM 676  N ND1 . HIS A 1 102 ? 141.181 123.139 178.753 1.00 44.21  ? 102 HIS R ND1 1 
ATOM 677  C CD2 . HIS A 1 102 ? 141.172 122.430 176.687 1.00 44.21  ? 102 HIS R CD2 1 
ATOM 678  C CE1 . HIS A 1 102 ? 142.050 122.147 178.677 1.00 44.21  ? 102 HIS R CE1 1 
ATOM 679  N NE2 . HIS A 1 102 ? 142.064 121.700 177.434 1.00 44.21  ? 102 HIS R NE2 1 
ATOM 680  N N   . TRP A 1 103 ? 141.863 125.155 174.889 1.00 44.42  ? 103 TRP R N   1 
ATOM 681  C CA  . TRP A 1 103 ? 142.438 124.790 173.594 1.00 44.42  ? 103 TRP R CA  1 
ATOM 682  C C   . TRP A 1 103 ? 143.268 123.525 173.750 1.00 44.42  ? 103 TRP R C   1 
ATOM 683  O O   . TRP A 1 103 ? 144.458 123.598 174.107 1.00 44.42  ? 103 TRP R O   1 
ATOM 684  C CB  . TRP A 1 103 ? 143.292 125.929 173.041 1.00 44.42  ? 103 TRP R CB  1 
ATOM 685  C CG  . TRP A 1 103 ? 143.961 125.607 171.740 1.00 44.42  ? 103 TRP R CG  1 
ATOM 686  C CD1 . TRP A 1 103 ? 145.241 125.171 171.562 1.00 44.42  ? 103 TRP R CD1 1 
ATOM 687  C CD2 . TRP A 1 103 ? 143.384 125.699 170.432 1.00 44.42  ? 103 TRP R CD2 1 
ATOM 688  N NE1 . TRP A 1 103 ? 145.497 124.983 170.226 1.00 44.42  ? 103 TRP R NE1 1 
ATOM 689  C CE2 . TRP A 1 103 ? 144.373 125.302 169.511 1.00 44.42  ? 103 TRP R CE2 1 
ATOM 690  C CE3 . TRP A 1 103 ? 142.128 126.079 169.951 1.00 44.42  ? 103 TRP R CE3 1 
ATOM 691  C CZ2 . TRP A 1 103 ? 144.143 125.272 168.137 1.00 44.42  ? 103 TRP R CZ2 1 
ATOM 692  C CZ3 . TRP A 1 103 ? 141.903 126.049 168.588 1.00 44.42  ? 103 TRP R CZ3 1 
ATOM 693  C CH2 . TRP A 1 103 ? 142.905 125.649 167.697 1.00 44.42  ? 103 TRP R CH2 1 
ATOM 694  N N   . PRO A 1 104 ? 142.698 122.343 173.493 1.00 43.55  ? 104 PRO R N   1 
ATOM 695  C CA  . PRO A 1 104 ? 143.469 121.105 173.671 1.00 43.55  ? 104 PRO R CA  1 
ATOM 696  C C   . PRO A 1 104 ? 144.427 120.806 172.534 1.00 43.55  ? 104 PRO R C   1 
ATOM 697  O O   . PRO A 1 104 ? 145.287 119.929 172.690 1.00 43.55  ? 104 PRO R O   1 
ATOM 698  C CB  . PRO A 1 104 ? 142.381 120.029 173.766 1.00 43.55  ? 104 PRO R CB  1 
ATOM 699  C CG  . PRO A 1 104 ? 141.262 120.572 172.935 1.00 43.55  ? 104 PRO R CG  1 
ATOM 700  C CD  . PRO A 1 104 ? 141.323 122.081 173.031 1.00 43.55  ? 104 PRO R CD  1 
ATOM 701  N N   . PHE A 1 105 ? 144.312 121.499 171.405 1.00 44.39  ? 105 PHE R N   1 
ATOM 702  C CA  . PHE A 1 105 ? 145.150 121.211 170.254 1.00 44.39  ? 105 PHE R CA  1 
ATOM 703  C C   . PHE A 1 105 ? 146.566 121.744 170.470 1.00 44.39  ? 105 PHE R C   1 
ATOM 704  O O   . PHE A 1 105 ? 146.842 122.513 171.395 1.00 44.39  ? 105 PHE R O   1 
ATOM 705  C CB  . PHE A 1 105 ? 144.539 121.808 168.988 1.00 44.39  ? 105 PHE R CB  1 
ATOM 706  C CG  . PHE A 1 105 ? 143.145 121.326 168.705 1.00 44.39  ? 105 PHE R CG  1 
ATOM 707  C CD1 . PHE A 1 105 ? 142.925 120.042 168.233 1.00 44.39  ? 105 PHE R CD1 1 
ATOM 708  C CD2 . PHE A 1 105 ? 142.055 122.153 168.916 1.00 44.39  ? 105 PHE R CD2 1 
ATOM 709  C CE1 . PHE A 1 105 ? 141.644 119.594 167.973 1.00 44.39  ? 105 PHE R CE1 1 
ATOM 710  C CE2 . PHE A 1 105 ? 140.771 121.710 168.659 1.00 44.39  ? 105 PHE R CE2 1 
ATOM 711  C CZ  . PHE A 1 105 ? 140.566 120.429 168.186 1.00 44.39  ? 105 PHE R CZ  1 
ATOM 712  N N   . GLY A 1 106 ? 147.474 121.317 169.592 1.00 42.29  ? 106 GLY R N   1 
ATOM 713  C CA  . GLY A 1 106 ? 148.861 121.706 169.701 1.00 42.29  ? 106 GLY R CA  1 
ATOM 714  C C   . GLY A 1 106 ? 149.116 123.133 169.256 1.00 42.29  ? 106 GLY R C   1 
ATOM 715  O O   . GLY A 1 106 ? 148.250 123.816 168.709 1.00 42.29  ? 106 GLY R O   1 
ATOM 716  N N   . ILE A 1 107 ? 150.347 123.585 169.508 1.00 43.66  ? 107 ILE R N   1 
ATOM 717  C CA  . ILE A 1 107 ? 150.740 124.939 169.132 1.00 43.66  ? 107 ILE R CA  1 
ATOM 718  C C   . ILE A 1 107 ? 150.773 125.097 167.616 1.00 43.66  ? 107 ILE R C   1 
ATOM 719  O O   . ILE A 1 107 ? 150.439 126.167 167.090 1.00 43.66  ? 107 ILE R O   1 
ATOM 720  C CB  . ILE A 1 107 ? 152.096 125.293 169.776 1.00 43.66  ? 107 ILE R CB  1 
ATOM 721  C CG1 . ILE A 1 107 ? 152.558 126.685 169.340 1.00 43.66  ? 107 ILE R CG1 1 
ATOM 722  C CG2 . ILE A 1 107 ? 153.144 124.237 169.449 1.00 43.66  ? 107 ILE R CG2 1 
ATOM 723  C CD1 . ILE A 1 107 ? 153.842 127.136 170.000 1.00 43.66  ? 107 ILE R CD1 1 
ATOM 724  N N   . TRP A 1 108 ? 151.171 124.048 166.891 1.00 47.34  ? 108 TRP R N   1 
ATOM 725  C CA  . TRP A 1 108 ? 151.260 124.140 165.437 1.00 47.34  ? 108 TRP R CA  1 
ATOM 726  C C   . TRP A 1 108 ? 149.896 124.400 164.809 1.00 47.34  ? 108 TRP R C   1 
ATOM 727  O O   . TRP A 1 108 ? 149.768 125.239 163.908 1.00 47.34  ? 108 TRP R O   1 
ATOM 728  C CB  . TRP A 1 108 ? 151.876 122.860 164.871 1.00 47.34  ? 108 TRP R CB  1 
ATOM 729  C CG  . TRP A 1 108 ? 153.229 122.546 165.433 1.00 47.34  ? 108 TRP R CG  1 
ATOM 730  C CD1 . TRP A 1 108 ? 153.526 121.619 166.389 1.00 47.34  ? 108 TRP R CD1 1 
ATOM 731  C CD2 . TRP A 1 108 ? 154.473 123.157 165.067 1.00 47.34  ? 108 TRP R CD2 1 
ATOM 732  N NE1 . TRP A 1 108 ? 154.876 121.617 166.645 1.00 47.34  ? 108 TRP R NE1 1 
ATOM 733  C CE2 . TRP A 1 108 ? 155.480 122.552 165.846 1.00 47.34  ? 108 TRP R CE2 1 
ATOM 734  C CE3 . TRP A 1 108 ? 154.832 124.157 164.159 1.00 47.34  ? 108 TRP R CE3 1 
ATOM 735  C CZ2 . TRP A 1 108 ? 156.821 122.914 165.743 1.00 47.34  ? 108 TRP R CZ2 1 
ATOM 736  C CZ3 . TRP A 1 108 ? 156.165 124.515 164.058 1.00 47.34  ? 108 TRP R CZ3 1 
ATOM 737  C CH2 . TRP A 1 108 ? 157.142 123.895 164.846 1.00 47.34  ? 108 TRP R CH2 1 
ATOM 738  N N   . LEU A 1 109 ? 148.862 123.691 165.270 1.00 45.42  ? 109 LEU R N   1 
ATOM 739  C CA  . LEU A 1 109 ? 147.528 123.886 164.712 1.00 45.42  ? 109 LEU R CA  1 
ATOM 740  C C   . LEU A 1 109 ? 146.995 125.280 165.021 1.00 45.42  ? 109 LEU R C   1 
ATOM 741  O O   . LEU A 1 109 ? 146.368 125.912 164.163 1.00 45.42  ? 109 LEU R O   1 
ATOM 742  C CB  . LEU A 1 109 ? 146.573 122.814 165.237 1.00 45.42  ? 109 LEU R CB  1 
ATOM 743  C CG  . LEU A 1 109 ? 145.151 122.868 164.675 1.00 45.42  ? 109 LEU R CG  1 
ATOM 744  C CD1 . LEU A 1 109 ? 145.163 122.639 163.173 1.00 45.42  ? 109 LEU R CD1 1 
ATOM 745  C CD2 . LEU A 1 109 ? 144.260 121.846 165.362 1.00 45.42  ? 109 LEU R CD2 1 
ATOM 746  N N   . CYS A 1 110 ? 147.227 125.773 166.240 1.00 45.70  ? 110 CYS R N   1 
ATOM 747  C CA  . CYS A 1 110 ? 146.783 127.119 166.590 1.00 45.70  ? 110 CYS R CA  1 
ATOM 748  C C   . CYS A 1 110 ? 147.498 128.169 165.747 1.00 45.70  ? 110 CYS R C   1 
ATOM 749  O O   . CYS A 1 110 ? 146.876 129.134 165.282 1.00 45.70  ? 110 CYS R O   1 
ATOM 750  C CB  . CYS A 1 110 ? 147.008 127.372 168.082 1.00 45.70  ? 110 CYS R CB  1 
ATOM 751  S SG  . CYS A 1 110 ? 146.385 128.959 168.685 1.00 45.70  ? 110 CYS R SG  1 
ATOM 752  N N   . LYS A 1 111 ? 148.805 127.994 165.534 1.00 42.54  ? 111 LYS R N   1 
ATOM 753  C CA  . LYS A 1 111 ? 149.554 128.906 164.673 1.00 42.54  ? 111 LYS R CA  1 
ATOM 754  C C   . LYS A 1 111 ? 149.012 128.885 163.249 1.00 42.54  ? 111 LYS R C   1 
ATOM 755  O O   . LYS A 1 111 ? 148.835 129.941 162.626 1.00 42.54  ? 111 LYS R O   1 
ATOM 756  C CB  . LYS A 1 111 ? 151.043 128.536 164.714 1.00 42.54  ? 111 LYS R CB  1 
ATOM 757  C CG  . LYS A 1 111 ? 152.020 129.444 163.947 1.00 42.54  ? 111 LYS R CG  1 
ATOM 758  C CD  . LYS A 1 111 ? 152.025 129.194 162.437 1.00 42.54  ? 111 LYS R CD  1 
ATOM 759  C CE  . LYS A 1 111 ? 152.616 130.363 161.672 1.00 42.54  ? 111 LYS R CE  1 
ATOM 760  N NZ  . LYS A 1 111 ? 152.347 130.265 160.211 1.00 42.54  ? 111 LYS R NZ  1 
ATOM 761  N N   . ALA A 1 112 ? 148.746 127.690 162.716 1.00 42.09  ? 112 ALA R N   1 
ATOM 762  C CA  . ALA A 1 112 ? 148.215 127.589 161.362 1.00 42.09  ? 112 ALA R CA  1 
ATOM 763  C C   . ALA A 1 112 ? 146.855 128.263 161.257 1.00 42.09  ? 112 ALA R C   1 
ATOM 764  O O   . ALA A 1 112 ? 146.587 128.986 160.290 1.00 42.09  ? 112 ALA R O   1 
ATOM 765  C CB  . ALA A 1 112 ? 148.125 126.123 160.940 1.00 42.09  ? 112 ALA R CB  1 
ATOM 766  N N   . ASN A 1 113 ? 145.987 128.043 162.249 1.00 39.64  ? 113 ASN R N   1 
ATOM 767  C CA  . ASN A 1 113 ? 144.666 128.661 162.237 1.00 39.64  ? 113 ASN R CA  1 
ATOM 768  C C   . ASN A 1 113 ? 144.769 130.180 162.293 1.00 39.64  ? 113 ASN R C   1 
ATOM 769  O O   . ASN A 1 113 ? 144.069 130.883 161.557 1.00 39.64  ? 113 ASN R O   1 
ATOM 770  C CB  . ASN A 1 113 ? 143.829 128.135 163.403 1.00 39.64  ? 113 ASN R CB  1 
ATOM 771  C CG  . ASN A 1 113 ? 142.369 128.529 163.299 1.00 39.64  ? 113 ASN R CG  1 
ATOM 772  O OD1 . ASN A 1 113 ? 141.924 129.048 162.275 1.00 39.64  ? 113 ASN R OD1 1 
ATOM 773  N ND2 . ASN A 1 113 ? 141.613 128.285 164.364 1.00 39.64  ? 113 ASN R ND2 1 
ATOM 774  N N   . SER A 1 114 ? 145.647 130.703 163.151 1.00 39.92  ? 114 SER R N   1 
ATOM 775  C CA  . SER A 1 114 ? 145.829 132.149 163.240 1.00 39.92  ? 114 SER R CA  1 
ATOM 776  C C   . SER A 1 114 ? 146.306 132.727 161.913 1.00 39.92  ? 114 SER R C   1 
ATOM 777  O O   . SER A 1 114 ? 145.763 133.728 161.420 1.00 39.92  ? 114 SER R O   1 
ATOM 778  C CB  . SER A 1 114 ? 146.820 132.472 164.359 1.00 39.92  ? 114 SER R CB  1 
ATOM 779  O OG  . SER A 1 114 ? 147.158 133.847 164.373 1.00 39.92  ? 114 SER R OG  1 
ATOM 780  N N   . PHE A 1 115 ? 147.319 132.097 161.312 1.00 39.03  ? 115 PHE R N   1 
ATOM 781  C CA  . PHE A 1 115 ? 147.876 132.613 160.066 1.00 39.03  ? 115 PHE R CA  1 
ATOM 782  C C   . PHE A 1 115 ? 146.844 132.581 158.946 1.00 39.03  ? 115 PHE R C   1 
ATOM 783  O O   . PHE A 1 115 ? 146.678 133.564 158.211 1.00 39.03  ? 115 PHE R O   1 
ATOM 784  C CB  . PHE A 1 115 ? 149.121 131.816 159.677 1.00 39.03  ? 115 PHE R CB  1 
ATOM 785  C CG  . PHE A 1 115 ? 149.873 132.399 158.516 1.00 39.03  ? 115 PHE R CG  1 
ATOM 786  C CD1 . PHE A 1 115 ? 150.435 133.662 158.603 1.00 39.03  ? 115 PHE R CD1 1 
ATOM 787  C CD2 . PHE A 1 115 ? 150.017 131.687 157.338 1.00 39.03  ? 115 PHE R CD2 1 
ATOM 788  C CE1 . PHE A 1 115 ? 151.127 134.204 157.537 1.00 39.03  ? 115 PHE R CE1 1 
ATOM 789  C CE2 . PHE A 1 115 ? 150.708 132.222 156.268 1.00 39.03  ? 115 PHE R CE2 1 
ATOM 790  C CZ  . PHE A 1 115 ? 151.264 133.482 156.368 1.00 39.03  ? 115 PHE R CZ  1 
ATOM 791  N N   . THR A 1 116 ? 146.127 131.462 158.805 1.00 36.25  ? 116 THR R N   1 
ATOM 792  C CA  . THR A 1 116 ? 145.155 131.361 157.722 1.00 36.25  ? 116 THR R CA  1 
ATOM 793  C C   . THR A 1 116 ? 143.968 132.288 157.957 1.00 36.25  ? 116 THR R C   1 
ATOM 794  O O   . THR A 1 116 ? 143.395 132.817 157.000 1.00 36.25  ? 116 THR R O   1 
ATOM 795  C CB  . THR A 1 116 ? 144.690 129.914 157.544 1.00 36.25  ? 116 THR R CB  1 
ATOM 796  O OG1 . THR A 1 116 ? 143.811 129.831 156.415 1.00 36.25  ? 116 THR R OG1 1 
ATOM 797  C CG2 . THR A 1 116 ? 143.955 129.427 158.772 1.00 36.25  ? 116 THR R CG2 1 
ATOM 798  N N   . ALA A 1 117 ? 143.594 132.517 159.220 1.00 35.19  ? 117 ALA R N   1 
ATOM 799  C CA  . ALA A 1 117 ? 142.506 133.445 159.502 1.00 35.19  ? 117 ALA R CA  1 
ATOM 800  C C   . ALA A 1 117 ? 142.888 134.869 159.122 1.00 35.19  ? 117 ALA R C   1 
ATOM 801  O O   . ALA A 1 117 ? 142.102 135.576 158.476 1.00 35.19  ? 117 ALA R O   1 
ATOM 802  C CB  . ALA A 1 117 ? 142.118 133.363 160.977 1.00 35.19  ? 117 ALA R CB  1 
ATOM 803  N N   . GLN A 1 118 ? 144.097 135.302 159.498 1.00 35.46  ? 118 GLN R N   1 
ATOM 804  C CA  . GLN A 1 118 ? 144.553 136.624 159.076 1.00 35.46  ? 118 GLN R CA  1 
ATOM 805  C C   . GLN A 1 118 ? 144.613 136.725 157.558 1.00 35.46  ? 118 GLN R C   1 
ATOM 806  O O   . GLN A 1 118 ? 144.161 137.721 156.976 1.00 35.46  ? 118 GLN R O   1 
ATOM 807  C CB  . GLN A 1 118 ? 145.921 136.940 159.680 1.00 35.46  ? 118 GLN R CB  1 
ATOM 808  C CG  . GLN A 1 118 ? 145.926 137.070 161.186 1.00 35.46  ? 118 GLN R CG  1 
ATOM 809  C CD  . GLN A 1 118 ? 145.058 138.215 161.671 1.00 35.46  ? 118 GLN R CD  1 
ATOM 810  O OE1 . GLN A 1 118 ? 143.999 138.001 162.259 1.00 35.46  ? 118 GLN R OE1 1 
ATOM 811  N NE2 . GLN A 1 118 ? 145.507 139.441 161.427 1.00 35.46  ? 118 GLN R NE2 1 
ATOM 812  N N   . LEU A 1 119 ? 145.154 135.695 156.901 1.00 30.69  ? 119 LEU R N   1 
ATOM 813  C CA  . LEU A 1 119 ? 145.264 135.719 155.446 1.00 30.69  ? 119 LEU R CA  1 
ATOM 814  C C   . LEU A 1 119 ? 143.894 135.853 154.795 1.00 30.69  ? 119 LEU R C   1 
ATOM 815  O O   . LEU A 1 119 ? 143.690 136.708 153.928 1.00 30.69  ? 119 LEU R O   1 
ATOM 816  C CB  . LEU A 1 119 ? 145.974 134.456 154.956 1.00 30.69  ? 119 LEU R CB  1 
ATOM 817  C CG  . LEU A 1 119 ? 145.955 134.191 153.449 1.00 30.69  ? 119 LEU R CG  1 
ATOM 818  C CD1 . LEU A 1 119 ? 146.648 135.310 152.690 1.00 30.69  ? 119 LEU R CD1 1 
ATOM 819  C CD2 . LEU A 1 119 ? 146.592 132.847 153.130 1.00 30.69  ? 119 LEU R CD2 1 
ATOM 820  N N   . ASN A 1 120 ? 142.934 135.028 155.222 1.00 30.22  ? 120 ASN R N   1 
ATOM 821  C CA  . ASN A 1 120 ? 141.610 135.051 154.610 1.00 30.22  ? 120 ASN R CA  1 
ATOM 822  C C   . ASN A 1 120 ? 140.898 136.373 154.862 1.00 30.22  ? 120 ASN R C   1 
ATOM 823  O O   . ASN A 1 120 ? 140.279 136.932 153.948 1.00 30.22  ? 120 ASN R O   1 
ATOM 824  C CB  . ASN A 1 120 ? 140.769 133.885 155.131 1.00 30.22  ? 120 ASN R CB  1 
ATOM 825  C CG  . ASN A 1 120 ? 141.284 132.541 154.659 1.00 30.22  ? 120 ASN R CG  1 
ATOM 826  O OD1 . ASN A 1 120 ? 141.390 131.596 155.441 1.00 30.22  ? 120 ASN R OD1 1 
ATOM 827  N ND2 . ASN A 1 120 ? 141.610 132.448 153.374 1.00 30.22  ? 120 ASN R ND2 1 
ATOM 828  N N   . MET A 1 121 ? 140.967 136.892 156.091 1.00 28.89  ? 121 MET R N   1 
ATOM 829  C CA  . MET A 1 121 ? 140.237 138.118 156.400 1.00 28.89  ? 121 MET R CA  1 
ATOM 830  C C   . MET A 1 121 ? 140.826 139.311 155.653 1.00 28.89  ? 121 MET R C   1 
ATOM 831  O O   . MET A 1 121 ? 140.089 140.120 155.070 1.00 28.89  ? 121 MET R O   1 
ATOM 832  C CB  . MET A 1 121 ? 140.221 138.350 157.912 1.00 28.89  ? 121 MET R CB  1 
ATOM 833  C CG  . MET A 1 121 ? 139.668 139.698 158.340 1.00 28.89  ? 121 MET R CG  1 
ATOM 834  S SD  . MET A 1 121 ? 140.064 140.092 160.057 1.00 28.89  ? 121 MET R SD  1 
ATOM 835  C CE  . MET A 1 121 ? 141.295 141.371 159.856 1.00 28.89  ? 121 MET R CE  1 
ATOM 836  N N   . PHE A 1 122 ? 142.160 139.427 155.635 1.00 27.75  ? 122 PHE R N   1 
ATOM 837  C CA  . PHE A 1 122 ? 142.784 140.499 154.866 1.00 27.75  ? 122 PHE R CA  1 
ATOM 838  C C   . PHE A 1 122 ? 142.505 140.354 153.376 1.00 27.75  ? 122 PHE R C   1 
ATOM 839  O O   . PHE A 1 122 ? 142.275 141.352 152.685 1.00 27.75  ? 122 PHE R O   1 
ATOM 840  C CB  . PHE A 1 122 ? 144.289 140.544 155.125 1.00 27.75  ? 122 PHE R CB  1 
ATOM 841  C CG  . PHE A 1 122 ? 144.677 141.363 156.322 1.00 27.75  ? 122 PHE R CG  1 
ATOM 842  C CD1 . PHE A 1 122 ? 143.728 141.787 157.235 1.00 27.75  ? 122 PHE R CD1 1 
ATOM 843  C CD2 . PHE A 1 122 ? 145.994 141.736 156.517 1.00 27.75  ? 122 PHE R CD2 1 
ATOM 844  C CE1 . PHE A 1 122 ? 144.093 142.552 158.328 1.00 27.75  ? 122 PHE R CE1 1 
ATOM 845  C CE2 . PHE A 1 122 ? 146.364 142.498 157.607 1.00 27.75  ? 122 PHE R CE2 1 
ATOM 846  C CZ  . PHE A 1 122 ? 145.411 142.906 158.513 1.00 27.75  ? 122 PHE R CZ  1 
ATOM 847  N N   . ALA A 1 123 ? 142.524 139.122 152.858 1.00 24.86  ? 123 ALA R N   1 
ATOM 848  C CA  . ALA A 1 123 ? 142.239 138.916 151.444 1.00 24.86  ? 123 ALA R CA  1 
ATOM 849  C C   . ALA A 1 123 ? 140.821 139.353 151.105 1.00 24.86  ? 123 ALA R C   1 
ATOM 850  O O   . ALA A 1 123 ? 140.595 140.030 150.098 1.00 24.86  ? 123 ALA R O   1 
ATOM 851  C CB  . ALA A 1 123 ? 142.456 137.448 151.075 1.00 24.86  ? 123 ALA R CB  1 
ATOM 852  N N   . SER A 1 124 ? 139.852 138.984 151.946 1.00 24.45  ? 124 SER R N   1 
ATOM 853  C CA  . SER A 1 124 ? 138.469 139.379 151.698 1.00 24.45  ? 124 SER R CA  1 
ATOM 854  C C   . SER A 1 124 ? 138.309 140.894 151.744 1.00 24.45  ? 124 SER R C   1 
ATOM 855  O O   . SER A 1 124 ? 137.647 141.484 150.879 1.00 24.45  ? 124 SER R O   1 
ATOM 856  C CB  . SER A 1 124 ? 137.543 138.710 152.713 1.00 24.45  ? 124 SER R CB  1 
ATOM 857  O OG  . SER A 1 124 ? 136.271 139.333 152.734 1.00 24.45  ? 124 SER R OG  1 
ATOM 858  N N   . VAL A 1 125 ? 138.920 141.543 152.740 1.00 23.69  ? 125 VAL R N   1 
ATOM 859  C CA  . VAL A 1 125 ? 138.806 142.996 152.851 1.00 23.69  ? 125 VAL R CA  1 
ATOM 860  C C   . VAL A 1 125 ? 139.426 143.677 151.636 1.00 23.69  ? 125 VAL R C   1 
ATOM 861  O O   . VAL A 1 125 ? 138.833 144.593 151.047 1.00 23.69  ? 125 VAL R O   1 
ATOM 862  C CB  . VAL A 1 125 ? 139.449 143.482 154.163 1.00 23.69  ? 125 VAL R CB  1 
ATOM 863  C CG1 . VAL A 1 125 ? 139.609 144.991 154.148 1.00 23.69  ? 125 VAL R CG1 1 
ATOM 864  C CG2 . VAL A 1 125 ? 138.614 143.043 155.355 1.00 23.69  ? 125 VAL R CG2 1 
ATOM 865  N N   . PHE A 1 126 ? 140.620 143.234 151.233 1.00 24.79  ? 126 PHE R N   1 
ATOM 866  C CA  . PHE A 1 126 ? 141.287 143.837 150.085 1.00 24.79  ? 126 PHE R CA  1 
ATOM 867  C C   . PHE A 1 126 ? 140.517 143.597 148.795 1.00 24.79  ? 126 PHE R C   1 
ATOM 868  O O   . PHE A 1 126 ? 140.464 144.480 147.933 1.00 24.79  ? 126 PHE R O   1 
ATOM 869  C CB  . PHE A 1 126 ? 142.711 143.297 149.963 1.00 24.79  ? 126 PHE R CB  1 
ATOM 870  C CG  . PHE A 1 126 ? 143.725 144.085 150.738 1.00 24.79  ? 126 PHE R CG  1 
ATOM 871  C CD1 . PHE A 1 126 ? 143.937 145.425 150.463 1.00 24.79  ? 126 PHE R CD1 1 
ATOM 872  C CD2 . PHE A 1 126 ? 144.468 143.486 151.742 1.00 24.79  ? 126 PHE R CD2 1 
ATOM 873  C CE1 . PHE A 1 126 ? 144.869 146.153 151.174 1.00 24.79  ? 126 PHE R CE1 1 
ATOM 874  C CE2 . PHE A 1 126 ? 145.402 144.209 152.456 1.00 24.79  ? 126 PHE R CE2 1 
ATOM 875  C CZ  . PHE A 1 126 ? 145.602 145.544 152.172 1.00 24.79  ? 126 PHE R CZ  1 
ATOM 876  N N   . PHE A 1 127 ? 139.922 142.412 148.637 1.00 22.28  ? 127 PHE R N   1 
ATOM 877  C CA  . PHE A 1 127 ? 139.149 142.136 147.433 1.00 22.28  ? 127 PHE R CA  1 
ATOM 878  C C   . PHE A 1 127 ? 137.894 142.997 147.376 1.00 22.28  ? 127 PHE R C   1 
ATOM 879  O O   . PHE A 1 127 ? 137.530 143.497 146.307 1.00 22.28  ? 127 PHE R O   1 
ATOM 880  C CB  . PHE A 1 127 ? 138.804 140.650 147.358 1.00 22.28  ? 127 PHE R CB  1 
ATOM 881  C CG  . PHE A 1 127 ? 139.932 139.798 146.846 1.00 22.28  ? 127 PHE R CG  1 
ATOM 882  C CD1 . PHE A 1 127 ? 140.663 140.192 145.738 1.00 22.28  ? 127 PHE R CD1 1 
ATOM 883  C CD2 . PHE A 1 127 ? 140.266 138.610 147.475 1.00 22.28  ? 127 PHE R CD2 1 
ATOM 884  C CE1 . PHE A 1 127 ? 141.705 139.417 145.266 1.00 22.28  ? 127 PHE R CE1 1 
ATOM 885  C CE2 . PHE A 1 127 ? 141.309 137.833 147.010 1.00 22.28  ? 127 PHE R CE2 1 
ATOM 886  C CZ  . PHE A 1 127 ? 142.027 138.236 145.903 1.00 22.28  ? 127 PHE R CZ  1 
ATOM 887  N N   . LEU A 1 128 ? 137.229 143.201 148.515 1.00 25.86  ? 128 LEU R N   1 
ATOM 888  C CA  . LEU A 1 128 ? 136.088 144.113 148.532 1.00 25.86  ? 128 LEU R CA  1 
ATOM 889  C C   . LEU A 1 128 ? 136.517 145.537 148.189 1.00 25.86  ? 128 LEU R C   1 
ATOM 890  O O   . LEU A 1 128 ? 135.834 146.238 147.426 1.00 25.86  ? 128 LEU R O   1 
ATOM 891  C CB  . LEU A 1 128 ? 135.401 144.069 149.896 1.00 25.86  ? 128 LEU R CB  1 
ATOM 892  C CG  . LEU A 1 128 ? 134.702 142.760 150.258 1.00 25.86  ? 128 LEU R CG  1 
ATOM 893  C CD1 . LEU A 1 128 ? 133.942 142.899 151.568 1.00 25.86  ? 128 LEU R CD1 1 
ATOM 894  C CD2 . LEU A 1 128 ? 133.774 142.335 149.136 1.00 25.86  ? 128 LEU R CD2 1 
ATOM 895  N N   . THR A 1 129 ? 137.652 145.979 148.737 1.00 21.65  ? 129 THR R N   1 
ATOM 896  C CA  . THR A 1 129 ? 138.137 147.327 148.456 1.00 21.65  ? 129 THR R CA  1 
ATOM 897  C C   . THR A 1 129 ? 138.460 147.501 146.976 1.00 21.65  ? 129 THR R C   1 
ATOM 898  O O   . THR A 1 129 ? 138.122 148.526 146.368 1.00 21.65  ? 129 THR R O   1 
ATOM 899  C CB  . THR A 1 129 ? 139.369 147.627 149.310 1.00 21.65  ? 129 THR R CB  1 
ATOM 900  O OG1 . THR A 1 129 ? 139.107 147.259 150.669 1.00 21.65  ? 129 THR R OG1 1 
ATOM 901  C CG2 . THR A 1 129 ? 139.713 149.107 149.247 1.00 21.65  ? 129 THR R CG2 1 
ATOM 902  N N   . VAL A 1 130 ? 139.120 146.507 146.377 1.00 22.90  ? 130 VAL R N   1 
ATOM 903  C CA  . VAL A 1 130 ? 139.470 146.617 144.966 1.00 22.90  ? 130 VAL R CA  1 
ATOM 904  C C   . VAL A 1 130 ? 138.224 146.509 144.096 1.00 22.90  ? 130 VAL R C   1 
ATOM 905  O O   . VAL A 1 130 ? 138.163 147.113 143.022 1.00 22.90  ? 130 VAL R O   1 
ATOM 906  C CB  . VAL A 1 130 ? 140.544 145.581 144.577 1.00 22.90  ? 130 VAL R CB  1 
ATOM 907  C CG1 . VAL A 1 130 ? 139.975 144.177 144.548 1.00 22.90  ? 130 VAL R CG1 1 
ATOM 908  C CG2 . VAL A 1 130 ? 141.168 145.938 143.234 1.00 22.90  ? 130 VAL R CG2 1 
ATOM 909  N N   . ILE A 1 131 ? 137.205 145.766 144.541 1.00 16.22  ? 131 ILE R N   1 
ATOM 910  C CA  . ILE A 1 131 ? 135.931 145.748 143.823 1.00 16.22  ? 131 ILE R CA  1 
ATOM 911  C C   . ILE A 1 131 ? 135.320 147.143 143.802 1.00 16.22  ? 131 ILE R C   1 
ATOM 912  O O   . ILE A 1 131 ? 134.863 147.628 142.758 1.00 16.22  ? 131 ILE R O   1 
ATOM 913  C CB  . ILE A 1 131 ? 134.969 144.728 144.460 1.00 16.22  ? 131 ILE R CB  1 
ATOM 914  C CG1 . ILE A 1 131 ? 135.342 143.305 144.053 1.00 16.22  ? 131 ILE R CG1 1 
ATOM 915  C CG2 . ILE A 1 131 ? 133.530 145.029 144.067 1.00 16.22  ? 131 ILE R CG2 1 
ATOM 916  C CD1 . ILE A 1 131 ? 134.593 142.241 144.824 1.00 16.22  ? 131 ILE R CD1 1 
ATOM 917  N N   . SER A 1 132 ? 135.305 147.808 144.960 1.00 23.20  ? 132 SER R N   1 
ATOM 918  C CA  . SER A 1 132 ? 134.747 149.157 145.025 1.00 23.20  ? 132 SER R CA  1 
ATOM 919  C C   . SER A 1 132 ? 135.534 150.125 144.147 1.00 23.20  ? 132 SER R C   1 
ATOM 920  O O   . SER A 1 132 ? 134.946 150.935 143.416 1.00 23.20  ? 132 SER R O   1 
ATOM 921  C CB  . SER A 1 132 ? 134.723 149.645 146.473 1.00 23.20  ? 132 SER R CB  1 
ATOM 922  O OG  . SER A 1 132 ? 133.835 148.867 147.257 1.00 23.20  ? 132 SER R OG  1 
ATOM 923  N N   . LEU A 1 133 ? 136.867 150.052 144.202 1.00 24.22  ? 133 LEU R N   1 
ATOM 924  C CA  . LEU A 1 133 ? 137.693 150.933 143.381 1.00 24.22  ? 133 LEU R CA  1 
ATOM 925  C C   . LEU A 1 133 ? 137.477 150.670 141.894 1.00 24.22  ? 133 LEU R C   1 
ATOM 926  O O   . LEU A 1 133 ? 137.397 151.610 141.093 1.00 24.22  ? 133 LEU R O   1 
ATOM 927  C CB  . LEU A 1 133 ? 139.167 150.763 143.749 1.00 24.22  ? 133 LEU R CB  1 
ATOM 928  C CG  . LEU A 1 133 ? 140.164 151.666 143.022 1.00 24.22  ? 133 LEU R CG  1 
ATOM 929  C CD1 . LEU A 1 133 ? 139.886 153.128 143.331 1.00 24.22  ? 133 LEU R CD1 1 
ATOM 930  C CD2 . LEU A 1 133 ? 141.591 151.298 143.396 1.00 24.22  ? 133 LEU R CD2 1 
ATOM 931  N N   . ASP A 1 134 ? 137.384 149.395 141.508 1.00 24.25  ? 134 ASP R N   1 
ATOM 932  C CA  . ASP A 1 134 ? 137.151 149.049 140.112 1.00 24.25  ? 134 ASP R CA  1 
ATOM 933  C C   . ASP A 1 134 ? 135.802 149.563 139.636 1.00 24.25  ? 134 ASP R C   1 
ATOM 934  O O   . ASP A 1 134 ? 135.685 150.058 138.514 1.00 24.25  ? 134 ASP R O   1 
ATOM 935  C CB  . ASP A 1 134 ? 137.244 147.535 139.924 1.00 24.25  ? 134 ASP R CB  1 
ATOM 936  C CG  . ASP A 1 134 ? 136.898 147.101 138.515 1.00 24.25  ? 134 ASP R CG  1 
ATOM 937  O OD1 . ASP A 1 134 ? 137.646 147.459 137.581 1.00 24.25  ? 134 ASP R OD1 1 
ATOM 938  O OD2 . ASP A 1 134 ? 135.877 146.404 138.340 1.00 24.25  ? 134 ASP R OD2 1 
ATOM 939  N N   . HIS A 1 135 ? 134.769 149.456 140.475 1.00 25.96  ? 135 HIS R N   1 
ATOM 940  C CA  . HIS A 1 135 ? 133.457 149.974 140.091 1.00 25.96  ? 135 HIS R CA  1 
ATOM 941  C C   . HIS A 1 135 ? 133.483 151.493 139.946 1.00 25.96  ? 135 HIS R C   1 
ATOM 942  O O   . HIS A 1 135 ? 132.875 152.051 139.019 1.00 25.96  ? 135 HIS R O   1 
ATOM 943  C CB  . HIS A 1 135 ? 132.409 149.544 141.116 1.00 25.96  ? 135 HIS R CB  1 
ATOM 944  C CG  . HIS A 1 135 ? 131.035 149.387 140.545 1.00 25.96  ? 135 HIS R CG  1 
ATOM 945  N ND1 . HIS A 1 135 ? 130.135 150.428 140.468 1.00 25.96  ? 135 HIS R ND1 1 
ATOM 946  C CD2 . HIS A 1 135 ? 130.407 148.308 140.019 1.00 25.96  ? 135 HIS R CD2 1 
ATOM 947  C CE1 . HIS A 1 135 ? 129.012 149.997 139.923 1.00 25.96  ? 135 HIS R CE1 1 
ATOM 948  N NE2 . HIS A 1 135 ? 129.151 148.715 139.640 1.00 25.96  ? 135 HIS R NE2 1 
ATOM 949  N N   . TYR A 1 136 ? 134.176 152.179 140.861 1.00 25.09  ? 136 TYR R N   1 
ATOM 950  C CA  . TYR A 1 136 ? 134.291 153.632 140.770 1.00 25.09  ? 136 TYR R CA  1 
ATOM 951  C C   . TYR A 1 136 ? 134.993 154.049 139.484 1.00 25.09  ? 136 TYR R C   1 
ATOM 952  O O   . TYR A 1 136 ? 134.555 154.978 138.796 1.00 25.09  ? 136 TYR R O   1 
ATOM 953  C CB  . TYR A 1 136 ? 135.036 154.178 141.988 1.00 25.09  ? 136 TYR R CB  1 
ATOM 954  C CG  . TYR A 1 136 ? 135.571 155.580 141.797 1.00 25.09  ? 136 TYR R CG  1 
ATOM 955  C CD1 . TYR A 1 136 ? 134.711 156.661 141.657 1.00 25.09  ? 136 TYR R CD1 1 
ATOM 956  C CD2 . TYR A 1 136 ? 136.938 155.822 141.755 1.00 25.09  ? 136 TYR R CD2 1 
ATOM 957  C CE1 . TYR A 1 136 ? 135.197 157.943 141.481 1.00 25.09  ? 136 TYR R CE1 1 
ATOM 958  C CE2 . TYR A 1 136 ? 137.433 157.101 141.580 1.00 25.09  ? 136 TYR R CE2 1 
ATOM 959  C CZ  . TYR A 1 136 ? 136.558 158.157 141.443 1.00 25.09  ? 136 TYR R CZ  1 
ATOM 960  O OH  . TYR A 1 136 ? 137.045 159.432 141.269 1.00 25.09  ? 136 TYR R OH  1 
ATOM 961  N N   . ILE A 1 137 ? 136.093 153.371 139.144 1.00 24.97  ? 137 ILE R N   1 
ATOM 962  C CA  . ILE A 1 137 ? 136.772 153.641 137.882 1.00 24.97  ? 137 ILE R CA  1 
ATOM 963  C C   . ILE A 1 137 ? 135.894 153.263 136.695 1.00 24.97  ? 137 ILE R C   1 
ATOM 964  O O   . ILE A 1 137 ? 135.974 153.894 135.634 1.00 24.97  ? 137 ILE R O   1 
ATOM 965  C CB  . ILE A 1 137 ? 138.125 152.903 137.846 1.00 24.97  ? 137 ILE R CB  1 
ATOM 966  C CG1 . ILE A 1 137 ? 139.030 153.403 138.973 1.00 24.97  ? 137 ILE R CG1 1 
ATOM 967  C CG2 . ILE A 1 137 ? 138.820 153.097 136.512 1.00 24.97  ? 137 ILE R CG2 1 
ATOM 968  C CD1 . ILE A 1 137 ? 140.272 152.565 139.176 1.00 24.97  ? 137 ILE R CD1 1 
ATOM 969  N N   . HIS A 1 138 ? 135.038 152.255 136.863 1.00 28.08  ? 138 HIS R N   1 
ATOM 970  C CA  . HIS A 1 138 ? 134.134 151.818 135.807 1.00 28.08  ? 138 HIS R CA  1 
ATOM 971  C C   . HIS A 1 138 ? 133.143 152.910 135.431 1.00 28.08  ? 138 HIS R C   1 
ATOM 972  O O   . HIS A 1 138 ? 133.134 153.394 134.293 1.00 28.08  ? 138 HIS R O   1 
ATOM 973  C CB  . HIS A 1 138 ? 133.400 150.557 136.269 1.00 28.08  ? 138 HIS R CB  1 
ATOM 974  C CG  . HIS A 1 138 ? 132.680 149.832 135.179 1.00 28.08  ? 138 HIS R CG  1 
ATOM 975  N ND1 . HIS A 1 138 ? 131.826 148.780 135.430 1.00 28.08  ? 138 HIS R ND1 1 
ATOM 976  C CD2 . HIS A 1 138 ? 132.665 150.018 133.839 1.00 28.08  ? 138 HIS R CD2 1 
ATOM 977  C CE1 . HIS A 1 138 ? 131.326 148.340 134.290 1.00 28.08  ? 138 HIS R CE1 1 
ATOM 978  N NE2 . HIS A 1 138 ? 131.817 149.075 133.310 1.00 28.08  ? 138 HIS R NE2 1 
ATOM 979  N N   . LEU A 1 139 ? 132.295 153.314 136.378 1.00 28.83  ? 139 LEU R N   1 
ATOM 980  C CA  . LEU A 1 139 ? 131.214 154.235 136.030 1.00 28.83  ? 139 LEU R CA  1 
ATOM 981  C C   . LEU A 1 139 ? 131.732 155.644 135.758 1.00 28.83  ? 139 LEU R C   1 
ATOM 982  O O   . LEU A 1 139 ? 131.337 156.279 134.773 1.00 28.83  ? 139 LEU R O   1 
ATOM 983  C CB  . LEU A 1 139 ? 130.149 154.245 137.125 1.00 28.83  ? 139 LEU R CB  1 
ATOM 984  C CG  . LEU A 1 139 ? 129.310 152.969 137.175 1.00 28.83  ? 139 LEU R CG  1 
ATOM 985  C CD1 . LEU A 1 139 ? 128.352 152.970 138.348 1.00 28.83  ? 139 LEU R CD1 1 
ATOM 986  C CD2 . LEU A 1 139 ? 128.546 152.837 135.878 1.00 28.83  ? 139 LEU R CD2 1 
ATOM 987  N N   . ILE A 1 140 ? 132.614 156.153 136.619 1.00 32.03  ? 140 ILE R N   1 
ATOM 988  C CA  . ILE A 1 140 ? 133.045 157.543 136.490 1.00 32.03  ? 140 ILE R CA  1 
ATOM 989  C C   . ILE A 1 140 ? 133.941 157.728 135.270 1.00 32.03  ? 140 ILE R C   1 
ATOM 990  O O   . ILE A 1 140 ? 133.773 158.682 134.501 1.00 32.03  ? 140 ILE R O   1 
ATOM 991  C CB  . ILE A 1 140 ? 133.741 158.006 137.782 1.00 32.03  ? 140 ILE R CB  1 
ATOM 992  C CG1 . ILE A 1 140 ? 132.756 157.975 138.952 1.00 32.03  ? 140 ILE R CG1 1 
ATOM 993  C CG2 . ILE A 1 140 ? 134.317 159.403 137.608 1.00 32.03  ? 140 ILE R CG2 1 
ATOM 994  C CD1 . ILE A 1 140 ? 131.524 158.827 138.736 1.00 32.03  ? 140 ILE R CD1 1 
ATOM 995  N N   . HIS A 1 141 ? 134.897 156.825 135.065 1.00 32.66  ? 141 HIS R N   1 
ATOM 996  C CA  . HIS A 1 141 ? 135.892 156.990 134.010 1.00 32.66  ? 141 HIS R CA  1 
ATOM 997  C C   . HIS A 1 141 ? 135.598 156.058 132.843 1.00 32.66  ? 141 HIS R C   1 
ATOM 998  O O   . HIS A 1 141 ? 135.727 154.832 132.989 1.00 32.66  ? 141 HIS R O   1 
ATOM 999  C CB  . HIS A 1 141 ? 137.296 156.731 134.558 1.00 32.66  ? 141 HIS R CB  1 
ATOM 1000 C CG  . HIS A 1 141 ? 137.720 157.705 135.612 1.00 32.66  ? 141 HIS R CG  1 
ATOM 1001 N ND1 . HIS A 1 141 ? 137.201 158.979 135.699 1.00 32.66  ? 141 HIS R ND1 1 
ATOM 1002 C CD2 . HIS A 1 141 ? 138.613 157.592 136.624 1.00 32.66  ? 141 HIS R CD2 1 
ATOM 1003 C CE1 . HIS A 1 141 ? 137.757 159.609 136.719 1.00 32.66  ? 141 HIS R CE1 1 
ATOM 1004 N NE2 . HIS A 1 141 ? 138.617 158.790 137.297 1.00 32.66  ? 141 HIS R NE2 1 
ATOM 1005 N N   . PRO A 1 142 ? 135.204 156.577 131.679 1.00 33.84  ? 142 PRO R N   1 
ATOM 1006 C CA  . PRO A 1 142 ? 134.945 155.700 130.531 1.00 33.84  ? 142 PRO R CA  1 
ATOM 1007 C C   . PRO A 1 142 ? 136.146 155.529 129.613 1.00 33.84  ? 142 PRO R C   1 
ATOM 1008 O O   . PRO A 1 142 ? 136.141 154.655 128.741 1.00 33.84  ? 142 PRO R O   1 
ATOM 1009 C CB  . PRO A 1 142 ? 133.798 156.414 129.808 1.00 33.84  ? 142 PRO R CB  1 
ATOM 1010 C CG  . PRO A 1 142 ? 133.935 157.872 130.197 1.00 33.84  ? 142 PRO R CG  1 
ATOM 1011 C CD  . PRO A 1 142 ? 134.850 157.978 131.395 1.00 33.84  ? 142 PRO R CD  1 
ATOM 1012 N N   . VAL A 1 143 ? 137.177 156.347 129.795 1.00 37.31  ? 143 VAL R N   1 
ATOM 1013 C CA  . VAL A 1 143 ? 138.327 156.368 128.895 1.00 37.31  ? 143 VAL R CA  1 
ATOM 1014 C C   . VAL A 1 143 ? 139.518 155.626 129.485 1.00 37.31  ? 143 VAL R C   1 
ATOM 1015 O O   . VAL A 1 143 ? 140.061 154.715 128.860 1.00 37.31  ? 143 VAL R O   1 
ATOM 1016 C CB  . VAL A 1 143 ? 138.697 157.824 128.535 1.00 37.31  ? 143 VAL R CB  1 
ATOM 1017 C CG1 . VAL A 1 143 ? 139.989 157.858 127.735 1.00 37.31  ? 143 VAL R CG1 1 
ATOM 1018 C CG2 . VAL A 1 143 ? 137.567 158.481 127.761 1.00 37.31  ? 143 VAL R CG2 1 
ATOM 1019 N N   . LEU A 1 144 ? 139.941 156.002 130.691 1.00 48.99  ? 144 LEU R N   1 
ATOM 1020 C CA  . LEU A 1 144 ? 141.094 155.360 131.310 1.00 48.99  ? 144 LEU R CA  1 
ATOM 1021 C C   . LEU A 1 144 ? 140.775 153.979 131.867 1.00 48.99  ? 144 LEU R C   1 
ATOM 1022 O O   . LEU A 1 144 ? 141.703 153.243 132.218 1.00 48.99  ? 144 LEU R O   1 
ATOM 1023 C CB  . LEU A 1 144 ? 141.671 156.263 132.408 1.00 48.99  ? 144 LEU R CB  1 
ATOM 1024 C CG  . LEU A 1 144 ? 140.834 156.662 133.629 1.00 48.99  ? 144 LEU R CG  1 
ATOM 1025 C CD1 . LEU A 1 144 ? 140.851 155.598 134.721 1.00 48.99  ? 144 LEU R CD1 1 
ATOM 1026 C CD2 . LEU A 1 144 ? 141.303 158.003 134.178 1.00 48.99  ? 144 LEU R CD2 1 
ATOM 1027 N N   . SER A 1 145 ? 139.496 153.613 131.962 1.00 48.99  ? 145 SER R N   1 
ATOM 1028 C CA  . SER A 1 145 ? 139.104 152.269 132.361 1.00 48.99  ? 145 SER R CA  1 
ATOM 1029 C C   . SER A 1 145 ? 138.961 151.320 131.180 1.00 48.99  ? 145 SER R C   1 
ATOM 1030 O O   . SER A 1 145 ? 138.857 150.107 131.390 1.00 48.99  ? 145 SER R O   1 
ATOM 1031 C CB  . SER A 1 145 ? 137.783 152.308 133.139 1.00 48.99  ? 145 SER R CB  1 
ATOM 1032 O OG  . SER A 1 145 ? 137.217 151.014 133.243 1.00 48.99  ? 145 SER R OG  1 
ATOM 1033 N N   . HIS A 1 146 ? 138.949 151.838 129.954 1.00 38.99  ? 146 HIS R N   1 
ATOM 1034 C CA  . HIS A 1 146 ? 138.885 151.011 128.758 1.00 38.99  ? 146 HIS R CA  1 
ATOM 1035 C C   . HIS A 1 146 ? 140.249 150.492 128.324 1.00 38.99  ? 146 HIS R C   1 
ATOM 1036 O O   . HIS A 1 146 ? 140.311 149.568 127.506 1.00 38.99  ? 146 HIS R O   1 
ATOM 1037 C CB  . HIS A 1 146 ? 138.247 151.800 127.609 1.00 38.99  ? 146 HIS R CB  1 
ATOM 1038 C CG  . HIS A 1 146 ? 137.865 150.957 126.433 1.00 38.99  ? 146 HIS R CG  1 
ATOM 1039 N ND1 . HIS A 1 146 ? 138.119 151.334 125.132 1.00 38.99  ? 146 HIS R ND1 1 
ATOM 1040 C CD2 . HIS A 1 146 ? 137.245 149.755 126.362 1.00 38.99  ? 146 HIS R CD2 1 
ATOM 1041 C CE1 . HIS A 1 146 ? 137.673 150.401 124.310 1.00 38.99  ? 146 HIS R CE1 1 
ATOM 1042 N NE2 . HIS A 1 146 ? 137.138 149.432 125.031 1.00 38.99  ? 146 HIS R NE2 1 
ATOM 1043 N N   . ARG A 1 147 ? 141.334 151.055 128.851 1.00 31.25  ? 147 ARG R N   1 
ATOM 1044 C CA  . ARG A 1 147 ? 142.684 150.650 128.488 1.00 31.25  ? 147 ARG R CA  1 
ATOM 1045 C C   . ARG A 1 147 ? 143.422 149.952 129.620 1.00 31.25  ? 147 ARG R C   1 
ATOM 1046 O O   . ARG A 1 147 ? 144.583 149.570 129.440 1.00 31.25  ? 147 ARG R O   1 
ATOM 1047 C CB  . ARG A 1 147 ? 143.492 151.867 128.023 1.00 31.25  ? 147 ARG R CB  1 
ATOM 1048 C CG  . ARG A 1 147 ? 142.926 152.555 126.793 1.00 31.25  ? 147 ARG R CG  1 
ATOM 1049 C CD  . ARG A 1 147 ? 143.706 153.815 126.457 1.00 31.25  ? 147 ARG R CD  1 
ATOM 1050 N NE  . ARG A 1 147 ? 145.073 153.519 126.046 1.00 31.25  ? 147 ARG R NE  1 
ATOM 1051 C CZ  . ARG A 1 147 ? 146.150 153.796 126.768 1.00 31.25  ? 147 ARG R CZ  1 
ATOM 1052 N NH1 . ARG A 1 147 ? 146.057 154.378 127.952 1.00 31.25  ? 147 ARG R NH1 1 
ATOM 1053 N NH2 . ARG A 1 147 ? 147.350 153.481 126.290 1.00 31.25  ? 147 ARG R NH2 1 
ATOM 1054 N N   . HIS A 1 148 ? 142.788 149.775 130.777 1.00 48.99  ? 148 HIS R N   1 
ATOM 1055 C CA  . HIS A 1 148 ? 143.432 149.161 131.934 1.00 48.99  ? 148 HIS R CA  1 
ATOM 1056 C C   . HIS A 1 148 ? 142.494 148.165 132.600 1.00 48.99  ? 148 HIS R C   1 
ATOM 1057 O O   . HIS A 1 148 ? 142.360 148.136 133.827 1.00 48.99  ? 148 HIS R O   1 
ATOM 1058 C CB  . HIS A 1 148 ? 143.892 150.221 132.934 1.00 48.99  ? 148 HIS R CB  1 
ATOM 1059 C CG  . HIS A 1 148 ? 144.949 151.136 132.399 1.00 48.99  ? 148 HIS R CG  1 
ATOM 1060 N ND1 . HIS A 1 148 ? 146.013 150.685 131.648 1.00 48.99  ? 148 HIS R ND1 1 
ATOM 1061 C CD2 . HIS A 1 148 ? 145.105 152.477 132.505 1.00 48.99  ? 148 HIS R CD2 1 
ATOM 1062 C CE1 . HIS A 1 148 ? 146.780 151.708 131.316 1.00 48.99  ? 148 HIS R CE1 1 
ATOM 1063 N NE2 . HIS A 1 148 ? 146.251 152.807 131.823 1.00 48.99  ? 148 HIS R NE2 1 
ATOM 1064 N N   . ARG A 1 149 ? 141.829 147.333 131.797 1.00 31.09  ? 149 ARG R N   1 
ATOM 1065 C CA  . ARG A 1 149 ? 140.906 146.328 132.312 1.00 31.09  ? 149 ARG R CA  1 
ATOM 1066 C C   . ARG A 1 149 ? 141.197 144.955 131.715 1.00 31.09  ? 149 ARG R C   1 
ATOM 1067 O O   . ARG A 1 149 ? 140.290 144.133 131.562 1.00 31.09  ? 149 ARG R O   1 
ATOM 1068 C CB  . ARG A 1 149 ? 139.456 146.732 132.049 1.00 31.09  ? 149 ARG R CB  1 
ATOM 1069 C CG  . ARG A 1 149 ? 138.479 146.253 133.111 1.00 31.09  ? 149 ARG R CG  1 
ATOM 1070 C CD  . ARG A 1 149 ? 137.045 146.601 132.748 1.00 31.09  ? 149 ARG R CD  1 
ATOM 1071 N NE  . ARG A 1 149 ? 136.094 146.093 133.729 1.00 31.09  ? 149 ARG R NE  1 
ATOM 1072 C CZ  . ARG A 1 149 ? 135.902 146.618 134.932 1.00 31.09  ? 149 ARG R CZ  1 
ATOM 1073 N NH1 . ARG A 1 149 ? 136.575 147.683 135.338 1.00 31.09  ? 149 ARG R NH1 1 
ATOM 1074 N NH2 . ARG A 1 149 ? 135.010 146.062 135.747 1.00 31.09  ? 149 ARG R NH2 1 
ATOM 1075 N N   . THR A 1 150 ? 142.454 144.695 131.372 1.00 26.43  ? 150 THR R N   1 
ATOM 1076 C CA  . THR A 1 150 ? 142.825 143.404 130.811 1.00 26.43  ? 150 THR R CA  1 
ATOM 1077 C C   . THR A 1 150 ? 142.782 142.319 131.881 1.00 26.43  ? 150 THR R C   1 
ATOM 1078 O O   . THR A 1 150 ? 142.914 142.587 133.079 1.00 26.43  ? 150 THR R O   1 
ATOM 1079 C CB  . THR A 1 150 ? 144.221 143.469 130.191 1.00 26.43  ? 150 THR R CB  1 
ATOM 1080 O OG1 . THR A 1 150 ? 145.105 144.174 131.072 1.00 26.43  ? 150 THR R OG1 1 
ATOM 1081 C CG2 . THR A 1 150 ? 144.174 144.186 128.850 1.00 26.43  ? 150 THR R CG2 1 
ATOM 1082 N N   . LEU A 1 151 ? 142.587 141.076 131.433 1.00 25.29  ? 151 LEU R N   1 
ATOM 1083 C CA  . LEU A 1 151 ? 142.544 139.951 132.363 1.00 25.29  ? 151 LEU R CA  1 
ATOM 1084 C C   . LEU A 1 151 ? 143.902 139.716 133.013 1.00 25.29  ? 151 LEU R C   1 
ATOM 1085 O O   . LEU A 1 151 ? 143.976 139.313 134.180 1.00 25.29  ? 151 LEU R O   1 
ATOM 1086 C CB  . LEU A 1 151 ? 142.066 138.691 131.643 1.00 25.29  ? 151 LEU R CB  1 
ATOM 1087 C CG  . LEU A 1 151 ? 140.603 138.682 131.194 1.00 25.29  ? 151 LEU R CG  1 
ATOM 1088 C CD1 . LEU A 1 151 ? 140.297 137.433 130.383 1.00 25.29  ? 151 LEU R CD1 1 
ATOM 1089 C CD2 . LEU A 1 151 ? 139.676 138.787 132.394 1.00 25.29  ? 151 LEU R CD2 1 
ATOM 1090 N N   . LYS A 1 152 ? 144.987 139.950 132.271 1.00 25.24  ? 152 LYS R N   1 
ATOM 1091 C CA  . LYS A 1 152 ? 146.319 139.788 132.846 1.00 25.24  ? 152 LYS R CA  1 
ATOM 1092 C C   . LYS A 1 152 ? 146.559 140.794 133.966 1.00 25.24  ? 152 LYS R C   1 
ATOM 1093 O O   . LYS A 1 152 ? 147.201 140.471 134.973 1.00 25.24  ? 152 LYS R O   1 
ATOM 1094 C CB  . LYS A 1 152 ? 147.384 139.910 131.753 1.00 25.24  ? 152 LYS R CB  1 
ATOM 1095 C CG  . LYS A 1 152 ? 147.527 141.295 131.141 1.00 25.24  ? 152 LYS R CG  1 
ATOM 1096 C CD  . LYS A 1 152 ? 148.120 141.220 129.744 1.00 25.24  ? 152 LYS R CD  1 
ATOM 1097 C CE  . LYS A 1 152 ? 148.520 142.597 129.241 1.00 25.24  ? 152 LYS R CE  1 
ATOM 1098 N NZ  . LYS A 1 152 ? 149.735 143.107 129.933 1.00 25.24  ? 152 LYS R NZ  1 
ATOM 1099 N N   . ASN A 1 153 ? 146.040 142.015 133.817 1.00 25.91  ? 153 ASN R N   1 
ATOM 1100 C CA  . ASN A 1 153 ? 146.142 142.996 134.893 1.00 25.91  ? 153 ASN R CA  1 
ATOM 1101 C C   . ASN A 1 153 ? 145.364 142.542 136.122 1.00 25.91  ? 153 ASN R C   1 
ATOM 1102 O O   . ASN A 1 153 ? 145.815 142.733 137.258 1.00 25.91  ? 153 ASN R O   1 
ATOM 1103 C CB  . ASN A 1 153 ? 145.644 144.358 134.411 1.00 25.91  ? 153 ASN R CB  1 
ATOM 1104 C CG  . ASN A 1 153 ? 146.512 145.500 134.897 1.00 25.91  ? 153 ASN R CG  1 
ATOM 1105 O OD1 . ASN A 1 153 ? 147.127 145.418 135.960 1.00 25.91  ? 153 ASN R OD1 1 
ATOM 1106 N ND2 . ASN A 1 153 ? 146.569 146.573 134.118 1.00 25.91  ? 153 ASN R ND2 1 
ATOM 1107 N N   . SER A 1 154 ? 144.190 141.940 135.913 1.00 24.20  ? 154 SER R N   1 
ATOM 1108 C CA  . SER A 1 154 ? 143.423 141.403 137.032 1.00 24.20  ? 154 SER R CA  1 
ATOM 1109 C C   . SER A 1 154 ? 144.183 140.286 137.735 1.00 24.20  ? 154 SER R C   1 
ATOM 1110 O O   . SER A 1 154 ? 144.203 140.219 138.970 1.00 24.20  ? 154 SER R O   1 
ATOM 1111 C CB  . SER A 1 154 ? 142.065 140.902 136.544 1.00 24.20  ? 154 SER R CB  1 
ATOM 1112 O OG  . SER A 1 154 ? 142.161 139.580 136.045 1.00 24.20  ? 154 SER R OG  1 
ATOM 1113 N N   . LEU A 1 155 ? 144.810 139.394 136.966 1.00 20.67  ? 155 LEU R N   1 
ATOM 1114 C CA  . LEU A 1 155 ? 145.615 138.340 137.576 1.00 20.67  ? 155 LEU R CA  1 
ATOM 1115 C C   . LEU A 1 155 ? 146.773 138.930 138.370 1.00 20.67  ? 155 LEU R C   1 
ATOM 1116 O O   . LEU A 1 155 ? 147.067 138.482 139.485 1.00 20.67  ? 155 LEU R O   1 
ATOM 1117 C CB  . LEU A 1 155 ? 146.128 137.383 136.500 1.00 20.67  ? 155 LEU R CB  1 
ATOM 1118 C CG  . LEU A 1 155 ? 145.069 136.531 135.799 1.00 20.67  ? 155 LEU R CG  1 
ATOM 1119 C CD1 . LEU A 1 155 ? 145.716 135.571 134.812 1.00 20.67  ? 155 LEU R CD1 1 
ATOM 1120 C CD2 . LEU A 1 155 ? 144.226 135.775 136.813 1.00 20.67  ? 155 LEU R CD2 1 
ATOM 1121 N N   . ILE A 1 156 ? 147.431 139.951 137.817 1.00 18.78  ? 156 ILE R N   1 
ATOM 1122 C CA  . ILE A 1 156 ? 148.551 140.583 138.508 1.00 18.78  ? 156 ILE R CA  1 
ATOM 1123 C C   . ILE A 1 156 ? 148.088 141.193 139.826 1.00 18.78  ? 156 ILE R C   1 
ATOM 1124 O O   . ILE A 1 156 ? 148.731 141.022 140.870 1.00 18.78  ? 156 ILE R O   1 
ATOM 1125 C CB  . ILE A 1 156 ? 149.214 141.634 137.599 1.00 18.78  ? 156 ILE R CB  1 
ATOM 1126 C CG1 . ILE A 1 156 ? 150.106 140.953 136.560 1.00 18.78  ? 156 ILE R CG1 1 
ATOM 1127 C CG2 . ILE A 1 156 ? 150.018 142.630 138.423 1.00 18.78  ? 156 ILE R CG2 1 
ATOM 1128 C CD1 . ILE A 1 156 ? 150.454 141.836 135.382 1.00 18.78  ? 156 ILE R CD1 1 
ATOM 1129 N N   . VAL A 1 157 ? 146.959 141.906 139.803 1.00 26.39  ? 157 VAL R N   1 
ATOM 1130 C CA  . VAL A 1 157 ? 146.519 142.585 141.019 1.00 26.39  ? 157 VAL R CA  1 
ATOM 1131 C C   . VAL A 1 157 ? 146.012 141.589 142.058 1.00 26.39  ? 157 VAL R C   1 
ATOM 1132 O O   . VAL A 1 157 ? 146.212 141.797 143.260 1.00 26.39  ? 157 VAL R O   1 
ATOM 1133 C CB  . VAL A 1 157 ? 145.472 143.674 140.710 1.00 26.39  ? 157 VAL R CB  1 
ATOM 1134 C CG1 . VAL A 1 157 ? 146.077 144.758 139.825 1.00 26.39  ? 157 VAL R CG1 1 
ATOM 1135 C CG2 . VAL A 1 157 ? 144.232 143.089 140.077 1.00 26.39  ? 157 VAL R CG2 1 
ATOM 1136 N N   . ILE A 1 158 ? 145.360 140.497 141.642 1.00 23.49  ? 158 ILE R N   1 
ATOM 1137 C CA  . ILE A 1 158 ? 144.931 139.510 142.633 1.00 23.49  ? 158 ILE R CA  1 
ATOM 1138 C C   . ILE A 1 158 ? 146.138 138.793 143.231 1.00 23.49  ? 158 ILE R C   1 
ATOM 1139 O O   . ILE A 1 158 ? 146.156 138.481 144.429 1.00 23.49  ? 158 ILE R O   1 
ATOM 1140 C CB  . ILE A 1 158 ? 143.906 138.518 142.043 1.00 23.49  ? 158 ILE R CB  1 
ATOM 1141 C CG1 . ILE A 1 158 ? 144.526 137.630 140.965 1.00 23.49  ? 158 ILE R CG1 1 
ATOM 1142 C CG2 . ILE A 1 158 ? 142.690 139.252 141.513 1.00 23.49  ? 158 ILE R CG2 1 
ATOM 1143 C CD1 . ILE A 1 158 ? 143.552 136.646 140.356 1.00 23.49  ? 158 ILE R CD1 1 
ATOM 1144 N N   . ILE A 1 159 ? 147.168 138.531 142.420 1.00 23.74  ? 159 ILE R N   1 
ATOM 1145 C CA  . ILE A 1 159 ? 148.394 137.945 142.957 1.00 23.74  ? 159 ILE R CA  1 
ATOM 1146 C C   . ILE A 1 159 ? 149.040 138.893 143.959 1.00 23.74  ? 159 ILE R C   1 
ATOM 1147 O O   . ILE A 1 159 ? 149.506 138.473 145.026 1.00 23.74  ? 159 ILE R O   1 
ATOM 1148 C CB  . ILE A 1 159 ? 149.358 137.576 141.814 1.00 23.74  ? 159 ILE R CB  1 
ATOM 1149 C CG1 . ILE A 1 159 ? 148.841 136.352 141.056 1.00 23.74  ? 159 ILE R CG1 1 
ATOM 1150 C CG2 . ILE A 1 159 ? 150.758 137.317 142.350 1.00 23.74  ? 159 ILE R CG2 1 
ATOM 1151 C CD1 . ILE A 1 159 ? 148.703 135.116 141.915 1.00 23.74  ? 159 ILE R CD1 1 
ATOM 1152 N N   . PHE A 1 160 ? 149.074 140.189 143.634 1.00 22.00  ? 160 PHE R N   1 
ATOM 1153 C CA  . PHE A 1 160 ? 149.636 141.171 144.556 1.00 22.00  ? 160 PHE R CA  1 
ATOM 1154 C C   . PHE A 1 160 ? 148.836 141.236 145.851 1.00 22.00  ? 160 PHE R C   1 
ATOM 1155 O O   . PHE A 1 160 ? 149.412 141.342 146.940 1.00 22.00  ? 160 PHE R O   1 
ATOM 1156 C CB  . PHE A 1 160 ? 149.690 142.545 143.887 1.00 22.00  ? 160 PHE R CB  1 
ATOM 1157 C CG  . PHE A 1 160 ? 150.238 143.630 144.771 1.00 22.00  ? 160 PHE R CG  1 
ATOM 1158 C CD1 . PHE A 1 160 ? 151.605 143.812 144.899 1.00 22.00  ? 160 PHE R CD1 1 
ATOM 1159 C CD2 . PHE A 1 160 ? 149.387 144.473 145.467 1.00 22.00  ? 160 PHE R CD2 1 
ATOM 1160 C CE1 . PHE A 1 160 ? 152.113 144.810 145.710 1.00 22.00  ? 160 PHE R CE1 1 
ATOM 1161 C CE2 . PHE A 1 160 ? 149.888 145.472 146.279 1.00 22.00  ? 160 PHE R CE2 1 
ATOM 1162 C CZ  . PHE A 1 160 ? 151.253 145.641 146.400 1.00 22.00  ? 160 PHE R CZ  1 
ATOM 1163 N N   . ILE A 1 161 ? 147.506 141.183 145.753 1.00 24.02  ? 161 ILE R N   1 
ATOM 1164 C CA  . ILE A 1 161 ? 146.660 141.216 146.943 1.00 24.02  ? 161 ILE R CA  1 
ATOM 1165 C C   . ILE A 1 161 ? 146.918 139.995 147.817 1.00 24.02  ? 161 ILE R C   1 
ATOM 1166 O O   . ILE A 1 161 ? 147.037 140.105 149.044 1.00 24.02  ? 161 ILE R O   1 
ATOM 1167 C CB  . ILE A 1 161 ? 145.177 141.323 146.539 1.00 24.02  ? 161 ILE R CB  1 
ATOM 1168 C CG1 . ILE A 1 161 ? 144.853 142.740 146.062 1.00 24.02  ? 161 ILE R CG1 1 
ATOM 1169 C CG2 . ILE A 1 161 ? 144.272 140.918 147.692 1.00 24.02  ? 161 ILE R CG2 1 
ATOM 1170 C CD1 . ILE A 1 161 ? 145.091 143.805 147.108 1.00 24.02  ? 161 ILE R CD1 1 
ATOM 1171 N N   . TRP A 1 162 ? 147.006 138.813 147.201 1.00 19.72  ? 162 TRP R N   1 
ATOM 1172 C CA  . TRP A 1 162 ? 147.287 137.602 147.965 1.00 19.72  ? 162 TRP R CA  1 
ATOM 1173 C C   . TRP A 1 162 ? 148.654 137.677 148.634 1.00 19.72  ? 162 TRP R C   1 
ATOM 1174 O O   . TRP A 1 162 ? 148.803 137.303 149.804 1.00 19.72  ? 162 TRP R O   1 
ATOM 1175 C CB  . TRP A 1 162 ? 147.202 136.376 147.055 1.00 19.72  ? 162 TRP R CB  1 
ATOM 1176 C CG  . TRP A 1 162 ? 145.820 135.810 146.920 1.00 19.72  ? 162 TRP R CG  1 
ATOM 1177 C CD1 . TRP A 1 162 ? 145.076 135.732 145.779 1.00 19.72  ? 162 TRP R CD1 1 
ATOM 1178 C CD2 . TRP A 1 162 ? 145.020 135.234 147.960 1.00 19.72  ? 162 TRP R CD2 1 
ATOM 1179 N NE1 . TRP A 1 162 ? 143.862 135.148 146.044 1.00 19.72  ? 162 TRP R NE1 1 
ATOM 1180 C CE2 . TRP A 1 162 ? 143.802 134.832 147.376 1.00 19.72  ? 162 TRP R CE2 1 
ATOM 1181 C CE3 . TRP A 1 162 ? 145.213 135.020 149.328 1.00 19.72  ? 162 TRP R CE3 1 
ATOM 1182 C CZ2 . TRP A 1 162 ? 142.783 134.230 148.111 1.00 19.72  ? 162 TRP R CZ2 1 
ATOM 1183 C CZ3 . TRP A 1 162 ? 144.200 134.422 150.057 1.00 19.72  ? 162 TRP R CZ3 1 
ATOM 1184 C CH2 . TRP A 1 162 ? 143.001 134.034 149.446 1.00 19.72  ? 162 TRP R CH2 1 
ATOM 1185 N N   . LEU A 1 163 ? 149.663 138.167 147.909 1.00 26.86  ? 163 LEU R N   1 
ATOM 1186 C CA  . LEU A 1 163 ? 151.001 138.287 148.480 1.00 26.86  ? 163 LEU R CA  1 
ATOM 1187 C C   . LEU A 1 163 ? 151.012 139.259 149.653 1.00 26.86  ? 163 LEU R C   1 
ATOM 1188 O O   . LEU A 1 163 ? 151.634 138.989 150.688 1.00 26.86  ? 163 LEU R O   1 
ATOM 1189 C CB  . LEU A 1 163 ? 151.989 138.723 147.395 1.00 26.86  ? 163 LEU R CB  1 
ATOM 1190 C CG  . LEU A 1 163 ? 153.494 138.758 147.682 1.00 26.86  ? 163 LEU R CG  1 
ATOM 1191 C CD1 . LEU A 1 163 ? 154.266 138.563 146.389 1.00 26.86  ? 163 LEU R CD1 1 
ATOM 1192 C CD2 . LEU A 1 163 ? 153.917 140.064 148.341 1.00 26.86  ? 163 LEU R CD2 1 
ATOM 1193 N N   . LEU A 1 164 ? 150.334 140.399 149.509 1.00 25.97  ? 164 LEU R N   1 
ATOM 1194 C CA  . LEU A 1 164 ? 150.261 141.382 150.581 1.00 25.97  ? 164 LEU R CA  1 
ATOM 1195 C C   . LEU A 1 164 ? 149.509 140.864 151.798 1.00 25.97  ? 164 LEU R C   1 
ATOM 1196 O O   . LEU A 1 164 ? 149.907 141.164 152.929 1.00 25.97  ? 164 LEU R O   1 
ATOM 1197 C CB  . LEU A 1 164 ? 149.600 142.665 150.073 1.00 25.97  ? 164 LEU R CB  1 
ATOM 1198 C CG  . LEU A 1 164 ? 149.502 143.830 151.059 1.00 25.97  ? 164 LEU R CG  1 
ATOM 1199 C CD1 . LEU A 1 164 ? 150.886 144.302 151.475 1.00 25.97  ? 164 LEU R CD1 1 
ATOM 1200 C CD2 . LEU A 1 164 ? 148.702 144.973 150.454 1.00 25.97  ? 164 LEU R CD2 1 
ATOM 1201 N N   . ALA A 1 165 ? 148.440 140.096 151.594 1.00 27.62  ? 165 ALA R N   1 
ATOM 1202 C CA  . ALA A 1 165 ? 147.706 139.510 152.706 1.00 27.62  ? 165 ALA R CA  1 
ATOM 1203 C C   . ALA A 1 165 ? 148.449 138.360 153.369 1.00 27.62  ? 165 ALA R C   1 
ATOM 1204 O O   . ALA A 1 165 ? 148.210 138.087 154.551 1.00 27.62  ? 165 ALA R O   1 
ATOM 1205 C CB  . ALA A 1 165 ? 146.332 139.022 152.235 1.00 27.62  ? 165 ALA R CB  1 
ATOM 1206 N N   . SER A 1 166 ? 149.338 137.681 152.643 1.00 29.08  ? 166 SER R N   1 
ATOM 1207 C CA  . SER A 1 166 ? 150.082 136.568 153.217 1.00 29.08  ? 166 SER R CA  1 
ATOM 1208 C C   . SER A 1 166 ? 151.385 136.994 153.881 1.00 29.08  ? 166 SER R C   1 
ATOM 1209 O O   . SER A 1 166 ? 151.836 136.326 154.818 1.00 29.08  ? 166 SER R O   1 
ATOM 1210 C CB  . SER A 1 166 ? 150.383 135.524 152.137 1.00 29.08  ? 166 SER R CB  1 
ATOM 1211 O OG  . SER A 1 166 ? 151.266 136.044 151.158 1.00 29.08  ? 166 SER R OG  1 
ATOM 1212 N N   . LEU A 1 167 ? 152.002 138.086 153.426 1.00 27.88  ? 167 LEU R N   1 
ATOM 1213 C CA  . LEU A 1 167 ? 153.283 138.534 153.959 1.00 27.88  ? 167 LEU R CA  1 
ATOM 1214 C C   . LEU A 1 167 ? 153.141 139.717 154.911 1.00 27.88  ? 167 LEU R C   1 
ATOM 1215 O O   . LEU A 1 167 ? 154.040 140.561 154.990 1.00 27.88  ? 167 LEU R O   1 
ATOM 1216 C CB  . LEU A 1 167 ? 154.235 138.885 152.816 1.00 27.88  ? 167 LEU R CB  1 
ATOM 1217 C CG  . LEU A 1 167 ? 155.034 137.717 152.236 1.00 27.88  ? 167 LEU R CG  1 
ATOM 1218 C CD1 . LEU A 1 167 ? 155.912 138.183 151.087 1.00 27.88  ? 167 LEU R CD1 1 
ATOM 1219 C CD2 . LEU A 1 167 ? 155.869 137.054 153.321 1.00 27.88  ? 167 LEU R CD2 1 
ATOM 1220 N N   . ILE A 1 168 ? 152.030 139.796 155.635 1.00 30.89  ? 168 ILE R N   1 
ATOM 1221 C CA  . ILE A 1 168 ? 151.780 140.872 156.587 1.00 30.89  ? 168 ILE R CA  1 
ATOM 1222 C C   . ILE A 1 168 ? 151.597 140.249 157.967 1.00 30.89  ? 168 ILE R C   1 
ATOM 1223 O O   . ILE A 1 168 ? 150.836 139.288 158.137 1.00 30.89  ? 168 ILE R O   1 
ATOM 1224 C CB  . ILE A 1 168 ? 150.575 141.732 156.173 1.00 30.89  ? 168 ILE R CB  1 
ATOM 1225 C CG1 . ILE A 1 168 ? 150.485 142.992 157.040 1.00 30.89  ? 168 ILE R CG1 1 
ATOM 1226 C CG2 . ILE A 1 168 ? 149.282 140.927 156.177 1.00 30.89  ? 168 ILE R CG2 1 
ATOM 1227 C CD1 . ILE A 1 168 ? 149.535 144.035 156.497 1.00 30.89  ? 168 ILE R CD1 1 
ATOM 1228 N N   . GLY A 1 169 ? 152.329 140.762 158.942 1.00 40.04  ? 169 GLY R N   1 
ATOM 1229 C CA  . GLY A 1 169 ? 152.241 140.287 160.313 1.00 40.04  ? 169 GLY R CA  1 
ATOM 1230 C C   . GLY A 1 169 ? 153.051 139.018 160.511 1.00 40.04  ? 169 GLY R C   1 
ATOM 1231 O O   . GLY A 1 169 ? 153.074 138.128 159.652 1.00 40.04  ? 169 GLY R O   1 
ATOM 1232 N N   . GLY A 1 170 ? 153.742 138.942 161.649 1.00 43.99  ? 170 GLY R N   1 
ATOM 1233 C CA  . GLY A 1 170 ? 154.493 137.764 162.027 1.00 43.99  ? 170 GLY R CA  1 
ATOM 1234 C C   . GLY A 1 170 ? 153.878 136.807 163.043 1.00 43.99  ? 170 GLY R C   1 
ATOM 1235 O O   . GLY A 1 170 ? 154.416 136.659 164.144 1.00 43.99  ? 170 GLY R O   1 
ATOM 1236 N N   . PRO A 1 171 ? 152.752 136.126 162.723 1.00 46.02  ? 171 PRO R N   1 
ATOM 1237 C CA  . PRO A 1 171 ? 152.342 135.001 163.582 1.00 46.02  ? 171 PRO R CA  1 
ATOM 1238 C C   . PRO A 1 171 ? 153.221 133.770 163.415 1.00 46.02  ? 171 PRO R C   1 
ATOM 1239 O O   . PRO A 1 171 ? 152.860 132.686 163.884 1.00 46.02  ? 171 PRO R O   1 
ATOM 1240 C CB  . PRO A 1 171 ? 150.907 134.692 163.135 1.00 46.02  ? 171 PRO R CB  1 
ATOM 1241 C CG  . PRO A 1 171 ? 150.477 135.782 162.280 1.00 46.02  ? 171 PRO R CG  1 
ATOM 1242 C CD  . PRO A 1 171 ? 151.607 136.700 161.996 1.00 46.02  ? 171 PRO R CD  1 
ATOM 1243 N N   . ALA A 1 172 ? 154.374 133.914 162.760 1.00 50.08  ? 172 ALA R N   1 
ATOM 1244 C CA  . ALA A 1 172 ? 155.211 132.773 162.386 1.00 50.08  ? 172 ALA R CA  1 
ATOM 1245 C C   . ALA A 1 172 ? 155.927 132.187 163.607 1.00 50.08  ? 172 ALA R C   1 
ATOM 1246 O O   . ALA A 1 172 ? 157.154 132.171 163.706 1.00 50.08  ? 172 ALA R O   1 
ATOM 1247 C CB  . ALA A 1 172 ? 156.203 133.184 161.307 1.00 50.08  ? 172 ALA R CB  1 
ATOM 1248 N N   . LEU A 1 173 ? 155.116 131.714 164.557 1.00 55.11  ? 173 LEU R N   1 
ATOM 1249 C CA  . LEU A 1 173 ? 155.572 130.984 165.738 1.00 55.11  ? 173 LEU R CA  1 
ATOM 1250 C C   . LEU A 1 173 ? 156.471 131.825 166.639 1.00 55.11  ? 173 LEU R C   1 
ATOM 1251 O O   . LEU A 1 173 ? 156.982 131.328 167.648 1.00 55.11  ? 173 LEU R O   1 
ATOM 1252 C CB  . LEU A 1 173 ? 156.295 129.698 165.327 1.00 55.11  ? 173 LEU R CB  1 
ATOM 1253 C CG  . LEU A 1 173 ? 156.145 128.517 166.289 1.00 55.11  ? 173 LEU R CG  1 
ATOM 1254 C CD1 . LEU A 1 173 ? 154.717 127.991 166.275 1.00 55.11  ? 173 LEU R CD1 1 
ATOM 1255 C CD2 . LEU A 1 173 ? 157.134 127.412 165.950 1.00 55.11  ? 173 LEU R CD2 1 
ATOM 1256 N N   . TYR A 1 174 ? 156.668 133.096 166.293 1.00 62.12  ? 174 TYR R N   1 
ATOM 1257 C CA  . TYR A 1 174 ? 157.457 134.002 167.114 1.00 62.12  ? 174 TYR R CA  1 
ATOM 1258 C C   . TYR A 1 174 ? 156.604 134.977 167.910 1.00 62.12  ? 174 TYR R C   1 
ATOM 1259 O O   . TYR A 1 174 ? 157.085 135.528 168.906 1.00 62.12  ? 174 TYR R O   1 
ATOM 1260 C CB  . TYR A 1 174 ? 158.442 134.791 166.243 1.00 62.12  ? 174 TYR R CB  1 
ATOM 1261 N N   . PHE A 1 175 ? 155.355 135.201 167.496 1.00 47.80  ? 175 PHE R N   1 
ATOM 1262 C CA  . PHE A 1 175 ? 154.453 136.125 168.173 1.00 47.80  ? 175 PHE R CA  1 
ATOM 1263 C C   . PHE A 1 175 ? 153.211 135.419 168.705 1.00 47.80  ? 175 PHE R C   1 
ATOM 1264 O O   . PHE A 1 175 ? 152.193 136.071 168.956 1.00 47.80  ? 175 PHE R O   1 
ATOM 1265 C CB  . PHE A 1 175 ? 154.045 137.262 167.233 1.00 47.80  ? 175 PHE R CB  1 
ATOM 1266 C CG  . PHE A 1 175 ? 155.031 138.396 167.182 1.00 47.80  ? 175 PHE R CG  1 
ATOM 1267 C CD1 . PHE A 1 175 ? 156.391 138.151 167.110 1.00 47.80  ? 175 PHE R CD1 1 
ATOM 1268 C CD2 . PHE A 1 175 ? 154.592 139.709 167.196 1.00 47.80  ? 175 PHE R CD2 1 
ATOM 1269 C CE1 . PHE A 1 175 ? 157.296 139.192 167.061 1.00 47.80  ? 175 PHE R CE1 1 
ATOM 1270 C CE2 . PHE A 1 175 ? 155.492 140.755 167.147 1.00 47.80  ? 175 PHE R CE2 1 
ATOM 1271 C CZ  . PHE A 1 175 ? 156.846 140.495 167.079 1.00 47.80  ? 175 PHE R CZ  1 
ATOM 1272 N N   . ARG A 1 176 ? 153.271 134.100 168.880 1.00 50.55  ? 176 ARG R N   1 
ATOM 1273 C CA  . ARG A 1 176 ? 152.114 133.335 169.340 1.00 50.55  ? 176 ARG R CA  1 
ATOM 1274 C C   . ARG A 1 176 ? 152.615 132.050 169.984 1.00 50.55  ? 176 ARG R C   1 
ATOM 1275 O O   . ARG A 1 176 ? 153.268 131.238 169.321 1.00 50.55  ? 176 ARG R O   1 
ATOM 1276 C CB  . ARG A 1 176 ? 151.160 133.038 168.186 1.00 50.55  ? 176 ARG R CB  1 
ATOM 1277 C CG  . ARG A 1 176 ? 149.858 132.387 168.612 1.00 50.55  ? 176 ARG R CG  1 
ATOM 1278 C CD  . ARG A 1 176 ? 148.895 132.268 167.446 1.00 50.55  ? 176 ARG R CD  1 
ATOM 1279 N NE  . ARG A 1 176 ? 147.646 131.627 167.838 1.00 50.55  ? 176 ARG R NE  1 
ATOM 1280 C CZ  . ARG A 1 176 ? 146.616 132.263 168.379 1.00 50.55  ? 176 ARG R CZ  1 
ATOM 1281 N NH1 . ARG A 1 176 ? 146.666 133.558 168.643 1.00 50.55  ? 176 ARG R NH1 1 
ATOM 1282 N NH2 . ARG A 1 176 ? 145.513 131.581 168.674 1.00 50.55  ? 176 ARG R NH2 1 
ATOM 1283 N N   . ASP A 1 177 ? 152.307 131.867 171.266 1.00 54.44  ? 177 ASP R N   1 
ATOM 1284 C CA  . ASP A 1 177 ? 152.742 130.703 172.025 1.00 54.44  ? 177 ASP R CA  1 
ATOM 1285 C C   . ASP A 1 177 ? 151.564 130.119 172.790 1.00 54.44  ? 177 ASP R C   1 
ATOM 1286 O O   . ASP A 1 177 ? 150.666 130.850 173.219 1.00 54.44  ? 177 ASP R O   1 
ATOM 1287 C CB  . ASP A 1 177 ? 153.869 131.064 173.001 1.00 54.44  ? 177 ASP R CB  1 
ATOM 1288 C CG  . ASP A 1 177 ? 155.164 131.413 172.295 1.00 54.44  ? 177 ASP R CG  1 
ATOM 1289 O OD1 . ASP A 1 177 ? 155.402 130.883 171.189 1.00 54.44  ? 177 ASP R OD1 1 
ATOM 1290 O OD2 . ASP A 1 177 ? 155.944 132.217 172.846 1.00 54.44  ? 177 ASP R OD2 1 
ATOM 1291 N N   . THR A 1 178 ? 151.574 128.799 172.959 1.00 51.52  ? 178 THR R N   1 
ATOM 1292 C CA  . THR A 1 178 ? 150.540 128.103 173.712 1.00 51.52  ? 178 THR R CA  1 
ATOM 1293 C C   . THR A 1 178 ? 150.994 127.916 175.154 1.00 51.52  ? 178 THR R C   1 
ATOM 1294 O O   . THR A 1 178 ? 151.992 127.238 175.415 1.00 51.52  ? 178 THR R O   1 
ATOM 1295 C CB  . THR A 1 178 ? 150.228 126.747 173.078 1.00 51.52  ? 178 THR R CB  1 
ATOM 1296 O OG1 . THR A 1 178 ? 149.952 126.921 171.683 1.00 51.52  ? 178 THR R OG1 1 
ATOM 1297 C CG2 . THR A 1 178 ? 149.027 126.102 173.752 1.00 51.52  ? 178 THR R CG2 1 
ATOM 1298 N N   . VAL A 1 179 ? 150.259 128.519 176.087 1.00 58.49  ? 179 VAL R N   1 
ATOM 1299 C CA  . VAL A 1 179 ? 150.567 128.433 177.511 1.00 58.49  ? 179 VAL R CA  1 
ATOM 1300 C C   . VAL A 1 179 ? 149.290 128.075 178.257 1.00 58.49  ? 179 VAL R C   1 
ATOM 1301 O O   . VAL A 1 179 ? 148.287 128.789 178.159 1.00 58.49  ? 179 VAL R O   1 
ATOM 1302 C CB  . VAL A 1 179 ? 151.156 129.749 178.054 1.00 58.49  ? 179 VAL R CB  1 
ATOM 1303 C CG1 . VAL A 1 179 ? 151.364 129.656 179.558 1.00 58.49  ? 179 VAL R CG1 1 
ATOM 1304 C CG2 . VAL A 1 179 ? 152.460 130.082 177.345 1.00 58.49  ? 179 VAL R CG2 1 
ATOM 1305 N N   . GLU A 1 180 ? 149.329 126.978 179.009 1.00 62.31  ? 180 GLU R N   1 
ATOM 1306 C CA  . GLU A 1 180 ? 148.156 126.519 179.743 1.00 62.31  ? 180 GLU R CA  1 
ATOM 1307 C C   . GLU A 1 180 ? 147.986 127.345 181.015 1.00 62.31  ? 180 GLU R C   1 
ATOM 1308 O O   . GLU A 1 180 ? 148.940 127.540 181.776 1.00 62.31  ? 180 GLU R O   1 
ATOM 1309 C CB  . GLU A 1 180 ? 148.271 125.025 180.051 1.00 62.31  ? 180 GLU R CB  1 
ATOM 1310 C CG  . GLU A 1 180 ? 149.317 124.644 181.089 1.00 62.31  ? 180 GLU R CG  1 
ATOM 1311 C CD  . GLU A 1 180 ? 149.819 123.223 180.917 1.00 62.31  ? 180 GLU R CD  1 
ATOM 1312 O OE1 . GLU A 1 180 ? 150.527 122.958 179.923 1.00 62.31  ? 180 GLU R OE1 1 
ATOM 1313 O OE2 . GLU A 1 180 ? 149.506 122.372 181.776 1.00 62.31  ? 180 GLU R OE2 1 
ATOM 1314 N N   . PHE A 1 181 ? 146.780 127.865 181.221 1.00 57.35  ? 181 PHE R N   1 
ATOM 1315 C CA  . PHE A 1 181 ? 146.453 128.627 182.417 1.00 57.35  ? 181 PHE R CA  1 
ATOM 1316 C C   . PHE A 1 181 ? 145.727 127.665 183.366 1.00 57.35  ? 181 PHE R C   1 
ATOM 1317 O O   . PHE A 1 181 ? 145.704 126.458 183.111 1.00 57.35  ? 181 PHE R O   1 
ATOM 1318 C CB  . PHE A 1 181 ? 145.706 129.900 181.993 1.00 57.35  ? 181 PHE R CB  1 
ATOM 1319 C CG  . PHE A 1 181 ? 145.349 130.824 183.122 1.00 57.35  ? 181 PHE R CG  1 
ATOM 1320 C CD1 . PHE A 1 181 ? 146.323 131.611 183.714 1.00 57.35  ? 181 PHE R CD1 1 
ATOM 1321 C CD2 . PHE A 1 181 ? 144.036 130.987 183.519 1.00 57.35  ? 181 PHE R CD2 1 
ATOM 1322 C CE1 . PHE A 1 181 ? 146.005 132.484 184.736 1.00 57.35  ? 181 PHE R CE1 1 
ATOM 1323 C CE2 . PHE A 1 181 ? 143.710 131.864 184.540 1.00 57.35  ? 181 PHE R CE2 1 
ATOM 1324 C CZ  . PHE A 1 181 ? 144.696 132.613 185.147 1.00 57.35  ? 181 PHE R CZ  1 
ATOM 1325 N N   . ASN A 1 182 ? 145.145 128.151 184.467 1.00 55.90  ? 182 ASN R N   1 
ATOM 1326 C CA  . ASN A 1 182 ? 144.723 127.237 185.529 1.00 55.90  ? 182 ASN R CA  1 
ATOM 1327 C C   . ASN A 1 182 ? 143.664 126.244 185.052 1.00 55.90  ? 182 ASN R C   1 
ATOM 1328 O O   . ASN A 1 182 ? 142.528 126.619 184.744 1.00 55.90  ? 182 ASN R O   1 
ATOM 1329 C CB  . ASN A 1 182 ? 144.218 128.006 186.760 1.00 55.90  ? 182 ASN R CB  1 
ATOM 1330 C CG  . ASN A 1 182 ? 143.101 128.986 186.444 1.00 55.90  ? 182 ASN R CG  1 
ATOM 1331 O OD1 . ASN A 1 182 ? 142.692 129.140 185.298 1.00 55.90  ? 182 ASN R OD1 1 
ATOM 1332 N ND2 . ASN A 1 182 ? 142.601 129.656 187.475 1.00 55.90  ? 182 ASN R ND2 1 
ATOM 1333 N N   . ASN A 1 183 ? 144.050 124.972 184.961 1.00 54.88  ? 183 ASN R N   1 
ATOM 1334 C CA  . ASN A 1 183 ? 143.193 123.857 184.566 1.00 54.88  ? 183 ASN R CA  1 
ATOM 1335 C C   . ASN A 1 183 ? 142.698 123.960 183.127 1.00 54.88  ? 183 ASN R C   1 
ATOM 1336 O O   . ASN A 1 183 ? 141.954 123.084 182.670 1.00 54.88  ? 183 ASN R O   1 
ATOM 1337 C CB  . ASN A 1 183 ? 141.995 123.705 185.516 1.00 54.88  ? 183 ASN R CB  1 
ATOM 1338 C CG  . ASN A 1 183 ? 142.416 123.532 186.962 1.00 54.88  ? 183 ASN R CG  1 
ATOM 1339 O OD1 . ASN A 1 183 ? 143.592 123.321 187.258 1.00 54.88  ? 183 ASN R OD1 1 
ATOM 1340 N ND2 . ASN A 1 183 ? 141.454 123.624 187.873 1.00 54.88  ? 183 ASN R ND2 1 
ATOM 1341 N N   . HIS A 1 184 ? 143.088 125.003 182.395 1.00 52.61  ? 184 HIS R N   1 
ATOM 1342 C CA  . HIS A 1 184 ? 142.661 125.177 181.013 1.00 52.61  ? 184 HIS R CA  1 
ATOM 1343 C C   . HIS A 1 184 ? 143.866 125.509 180.148 1.00 52.61  ? 184 HIS R C   1 
ATOM 1344 O O   . HIS A 1 184 ? 144.602 126.455 180.444 1.00 52.61  ? 184 HIS R O   1 
ATOM 1345 C CB  . HIS A 1 184 ? 141.606 126.285 180.888 1.00 52.61  ? 184 HIS R CB  1 
ATOM 1346 C CG  . HIS A 1 184 ? 140.284 125.941 181.502 1.00 52.61  ? 184 HIS R CG  1 
ATOM 1347 N ND1 . HIS A 1 184 ? 139.977 124.677 181.957 1.00 52.61  ? 184 HIS R ND1 1 
ATOM 1348 C CD2 . HIS A 1 184 ? 139.186 126.700 181.730 1.00 52.61  ? 184 HIS R CD2 1 
ATOM 1349 C CE1 . HIS A 1 184 ? 138.748 124.672 182.442 1.00 52.61  ? 184 HIS R CE1 1 
ATOM 1350 N NE2 . HIS A 1 184 ? 138.246 125.887 182.316 1.00 52.61  ? 184 HIS R NE2 1 
ATOM 1351 N N   . THR A 1 185 ? 144.062 124.734 179.085 1.00 48.86  ? 185 THR R N   1 
ATOM 1352 C CA  . THR A 1 185 ? 145.086 125.056 178.105 1.00 48.86  ? 185 THR R CA  1 
ATOM 1353 C C   . THR A 1 185 ? 144.641 126.238 177.247 1.00 48.86  ? 185 THR R C   1 
ATOM 1354 O O   . THR A 1 185 ? 143.448 126.475 177.038 1.00 48.86  ? 185 THR R O   1 
ATOM 1355 C CB  . THR A 1 185 ? 145.388 123.846 177.222 1.00 48.86  ? 185 THR R CB  1 
ATOM 1356 O OG1 . THR A 1 185 ? 144.164 123.324 176.689 1.00 48.86  ? 185 THR R OG1 1 
ATOM 1357 C CG2 . THR A 1 185 ? 146.089 122.760 178.025 1.00 48.86  ? 185 THR R CG2 1 
ATOM 1358 N N   . LEU A 1 186 ? 145.622 126.985 176.745 1.00 51.93  ? 186 LEU R N   1 
ATOM 1359 C CA  . LEU A 1 186 ? 145.328 128.211 176.014 1.00 51.93  ? 186 LEU R CA  1 
ATOM 1360 C C   . LEU A 1 186 ? 146.473 128.528 175.066 1.00 51.93  ? 186 LEU R C   1 
ATOM 1361 O O   . LEU A 1 186 ? 147.641 128.465 175.461 1.00 51.93  ? 186 LEU R O   1 
ATOM 1362 C CB  . LEU A 1 186 ? 145.101 129.376 176.985 1.00 51.93  ? 186 LEU R CB  1 
ATOM 1363 C CG  . LEU A 1 186 ? 144.766 130.743 176.388 1.00 51.93  ? 186 LEU R CG  1 
ATOM 1364 C CD1 . LEU A 1 186 ? 143.422 130.704 175.683 1.00 51.93  ? 186 LEU R CD1 1 
ATOM 1365 C CD2 . LEU A 1 186 ? 144.780 131.810 177.471 1.00 51.93  ? 186 LEU R CD2 1 
ATOM 1366 N N   . CYS A 1 187 ? 146.137 128.870 173.825 1.00 50.04  ? 187 CYS R N   1 
ATOM 1367 C CA  . CYS A 1 187 ? 147.099 129.376 172.854 1.00 50.04  ? 187 CYS R CA  1 
ATOM 1368 C C   . CYS A 1 187 ? 146.731 130.814 172.516 1.00 50.04  ? 187 CYS R C   1 
ATOM 1369 O O   . CYS A 1 187 ? 145.557 131.121 172.286 1.00 50.04  ? 187 CYS R O   1 
ATOM 1370 C CB  . CYS A 1 187 ? 147.135 128.509 171.591 1.00 50.04  ? 187 CYS R CB  1 
ATOM 1371 S SG  . CYS A 1 187 ? 145.661 128.560 170.542 1.00 50.04  ? 187 CYS R SG  1 
ATOM 1372 N N   . TYR A 1 188 ? 147.730 131.693 172.504 1.00 52.49  ? 188 TYR R N   1 
ATOM 1373 C CA  . TYR A 1 188 ? 147.477 133.121 172.387 1.00 52.49  ? 188 TYR R CA  1 
ATOM 1374 C C   . TYR A 1 188 ? 148.682 133.798 171.752 1.00 52.49  ? 188 TYR R C   1 
ATOM 1375 O O   . TYR A 1 188 ? 149.783 133.244 171.716 1.00 52.49  ? 188 TYR R O   1 
ATOM 1376 C CB  . TYR A 1 188 ? 147.181 133.737 173.760 1.00 52.49  ? 188 TYR R CB  1 
ATOM 1377 C CG  . TYR A 1 188 ? 148.349 133.653 174.719 1.00 52.49  ? 188 TYR R CG  1 
ATOM 1378 C CD1 . TYR A 1 188 ? 148.511 132.555 175.553 1.00 52.49  ? 188 TYR R CD1 1 
ATOM 1379 C CD2 . TYR A 1 188 ? 149.282 134.679 174.801 1.00 52.49  ? 188 TYR R CD2 1 
ATOM 1380 C CE1 . TYR A 1 188 ? 149.577 132.475 176.429 1.00 52.49  ? 188 TYR R CE1 1 
ATOM 1381 C CE2 . TYR A 1 188 ? 150.348 134.608 175.673 1.00 52.49  ? 188 TYR R CE2 1 
ATOM 1382 C CZ  . TYR A 1 188 ? 150.491 133.506 176.486 1.00 52.49  ? 188 TYR R CZ  1 
ATOM 1383 O OH  . TYR A 1 188 ? 151.553 133.435 177.358 1.00 52.49  ? 188 TYR R OH  1 
ATOM 1384 N N   . ASN A 1 189 ? 148.461 135.016 171.263 1.00 51.46  ? 189 ASN R N   1 
ATOM 1385 C CA  . ASN A 1 189 ? 149.546 135.830 170.730 1.00 51.46  ? 189 ASN R CA  1 
ATOM 1386 C C   . ASN A 1 189 ? 150.353 136.408 171.885 1.00 51.46  ? 189 ASN R C   1 
ATOM 1387 O O   . ASN A 1 189 ? 149.799 137.081 172.761 1.00 51.46  ? 189 ASN R O   1 
ATOM 1388 C CB  . ASN A 1 189 ? 148.998 136.947 169.844 1.00 51.46  ? 189 ASN R CB  1 
ATOM 1389 C CG  . ASN A 1 189 ? 148.054 136.436 168.775 1.00 51.46  ? 189 ASN R CG  1 
ATOM 1390 O OD1 . ASN A 1 189 ? 148.143 135.285 168.351 1.00 51.46  ? 189 ASN R OD1 1 
ATOM 1391 N ND2 . ASN A 1 189 ? 147.144 137.295 168.330 1.00 51.46  ? 189 ASN R ND2 1 
ATOM 1392 N N   . ASN A 1 190 ? 151.657 136.151 171.886 1.00 54.95  ? 190 ASN R N   1 
ATOM 1393 C CA  . ASN A 1 190 ? 152.550 136.567 172.966 1.00 54.95  ? 190 ASN R CA  1 
ATOM 1394 C C   . ASN A 1 190 ? 153.552 137.574 172.404 1.00 54.95  ? 190 ASN R C   1 
ATOM 1395 O O   . ASN A 1 190 ? 154.583 137.200 171.844 1.00 54.95  ? 190 ASN R O   1 
ATOM 1396 C CB  . ASN A 1 190 ? 153.253 135.362 173.585 1.00 54.95  ? 190 ASN R CB  1 
ATOM 1397 C CG  . ASN A 1 190 ? 154.012 135.715 174.848 1.00 54.95  ? 190 ASN R CG  1 
ATOM 1398 O OD1 . ASN A 1 190 ? 153.519 136.460 175.694 1.00 54.95  ? 190 ASN R OD1 1 
ATOM 1399 N ND2 . ASN A 1 190 ? 155.219 135.178 174.983 1.00 54.95  ? 190 ASN R ND2 1 
ATOM 1400 N N   . PHE A 1 191 ? 153.240 138.860 172.562 1.00 54.45  ? 191 PHE R N   1 
ATOM 1401 C CA  . PHE A 1 191 ? 154.147 139.917 172.133 1.00 54.45  ? 191 PHE R CA  1 
ATOM 1402 C C   . PHE A 1 191 ? 155.102 140.285 173.262 1.00 54.45  ? 191 PHE R C   1 
ATOM 1403 O O   . PHE A 1 191 ? 155.253 141.466 173.593 1.00 54.45  ? 191 PHE R O   1 
ATOM 1404 C CB  . PHE A 1 191 ? 153.368 141.156 171.681 1.00 54.45  ? 191 PHE R CB  1 
ATOM 1405 C CG  . PHE A 1 191 ? 152.174 140.850 170.820 1.00 54.45  ? 191 PHE R CG  1 
ATOM 1406 C CD1 . PHE A 1 191 ? 150.941 140.573 171.389 1.00 54.45  ? 191 PHE R CD1 1 
ATOM 1407 C CD2 . PHE A 1 191 ? 152.282 140.850 169.440 1.00 54.45  ? 191 PHE R CD2 1 
ATOM 1408 C CE1 . PHE A 1 191 ? 149.843 140.295 170.598 1.00 54.45  ? 191 PHE R CE1 1 
ATOM 1409 C CE2 . PHE A 1 191 ? 151.188 140.573 168.644 1.00 54.45  ? 191 PHE R CE2 1 
ATOM 1410 C CZ  . PHE A 1 191 ? 149.967 140.296 169.223 1.00 54.45  ? 191 PHE R CZ  1 
ATOM 1411 N N   . GLN A 1 192 ? 155.755 139.286 173.844 1.00 64.21  ? 192 GLN R N   1 
ATOM 1412 C CA  . GLN A 1 192 ? 156.669 139.480 174.966 1.00 64.21  ? 192 GLN R CA  1 
ATOM 1413 C C   . GLN A 1 192 ? 157.395 138.162 175.209 1.00 64.21  ? 192 GLN R C   1 
ATOM 1414 O O   . GLN A 1 192 ? 157.234 137.196 174.457 1.00 64.21  ? 192 GLN R O   1 
ATOM 1415 C CB  . GLN A 1 192 ? 155.930 139.948 176.222 1.00 64.21  ? 192 GLN R CB  1 
ATOM 1416 N N   . LYS A 1 193 ? 158.220 138.146 176.259 1.00 70.72  ? 193 LYS R N   1 
ATOM 1417 C CA  . LYS A 1 193 ? 158.934 136.958 176.723 1.00 70.72  ? 193 LYS R CA  1 
ATOM 1418 C C   . LYS A 1 193 ? 160.004 136.504 175.735 1.00 70.72  ? 193 LYS R C   1 
ATOM 1419 O O   . LYS A 1 193 ? 160.711 135.524 175.990 1.00 70.72  ? 193 LYS R O   1 
ATOM 1420 C CB  . LYS A 1 193 ? 157.956 135.812 177.008 1.00 70.72  ? 193 LYS R CB  1 
ATOM 1421 N N   . HIS A 1 194 ? 160.136 137.206 174.608 1.00 69.01  ? 194 HIS R N   1 
ATOM 1422 C CA  . HIS A 1 194 ? 161.200 136.890 173.662 1.00 69.01  ? 194 HIS R CA  1 
ATOM 1423 C C   . HIS A 1 194 ? 162.418 137.779 173.879 1.00 69.01  ? 194 HIS R C   1 
ATOM 1424 O O   . HIS A 1 194 ? 163.557 137.330 173.706 1.00 69.01  ? 194 HIS R O   1 
ATOM 1425 C CB  . HIS A 1 194 ? 160.690 137.025 172.226 1.00 69.01  ? 194 HIS R CB  1 
ATOM 1426 C CG  . HIS A 1 194 ? 159.686 135.985 171.839 1.00 69.01  ? 194 HIS R CG  1 
ATOM 1427 N ND1 . HIS A 1 194 ? 160.043 134.781 171.272 1.00 69.01  ? 194 HIS R ND1 1 
ATOM 1428 C CD2 . HIS A 1 194 ? 158.335 135.971 171.932 1.00 69.01  ? 194 HIS R CD2 1 
ATOM 1429 C CE1 . HIS A 1 194 ? 158.956 134.068 171.035 1.00 69.01  ? 194 HIS R CE1 1 
ATOM 1430 N NE2 . HIS A 1 194 ? 157.906 134.767 171.427 1.00 69.01  ? 194 HIS R NE2 1 
ATOM 1431 N N   . ASP A 1 195 ? 162.198 139.035 174.259 1.00 80.12  ? 195 ASP R N   1 
ATOM 1432 C CA  . ASP A 1 195 ? 163.280 139.974 174.520 1.00 80.12  ? 195 ASP R CA  1 
ATOM 1433 C C   . ASP A 1 195 ? 162.788 141.085 175.440 1.00 80.12  ? 195 ASP R C   1 
ATOM 1434 O O   . ASP A 1 195 ? 161.733 141.680 175.184 1.00 80.12  ? 195 ASP R O   1 
ATOM 1435 C CB  . ASP A 1 195 ? 163.818 140.559 173.213 1.00 80.12  ? 195 ASP R CB  1 
ATOM 1436 N N   . PRO A 1 196 ? 163.511 141.383 176.522 1.00 84.19  ? 196 PRO R N   1 
ATOM 1437 C CA  . PRO A 1 196 ? 163.077 142.472 177.413 1.00 84.19  ? 196 PRO R CA  1 
ATOM 1438 C C   . PRO A 1 196 ? 163.006 143.824 176.727 1.00 84.19  ? 196 PRO R C   1 
ATOM 1439 O O   . PRO A 1 196 ? 162.214 144.679 177.144 1.00 84.19  ? 196 PRO R O   1 
ATOM 1440 C CB  . PRO A 1 196 ? 164.138 142.457 178.523 1.00 84.19  ? 196 PRO R CB  1 
ATOM 1441 C CG  . PRO A 1 196 ? 164.709 141.075 178.487 1.00 84.19  ? 196 PRO R CG  1 
ATOM 1442 C CD  . PRO A 1 196 ? 164.696 140.680 177.041 1.00 84.19  ? 196 PRO R CD  1 
ATOM 1443 N N   . ASP A 1 197 ? 163.816 144.047 175.688 1.00 82.58  ? 197 ASP R N   1 
ATOM 1444 C CA  . ASP A 1 197 ? 163.777 145.321 174.978 1.00 82.58  ? 197 ASP R CA  1 
ATOM 1445 C C   . ASP A 1 197 ? 162.447 145.527 174.265 1.00 82.58  ? 197 ASP R C   1 
ATOM 1446 O O   . ASP A 1 197 ? 161.998 146.669 174.108 1.00 82.58  ? 197 ASP R O   1 
ATOM 1447 C CB  . ASP A 1 197 ? 164.932 145.402 173.980 1.00 82.58  ? 197 ASP R CB  1 
ATOM 1448 N N   . LEU A 1 198 ? 161.804 144.444 173.827 1.00 75.38  ? 198 LEU R N   1 
ATOM 1449 C CA  . LEU A 1 198 ? 160.518 144.525 173.132 1.00 75.38  ? 198 LEU R CA  1 
ATOM 1450 C C   . LEU A 1 198 ? 159.401 144.707 174.161 1.00 75.38  ? 198 LEU R C   1 
ATOM 1451 O O   . LEU A 1 198 ? 158.602 143.811 174.440 1.00 75.38  ? 198 LEU R O   1 
ATOM 1452 C CB  . LEU A 1 198 ? 160.291 143.289 172.271 1.00 75.38  ? 198 LEU R CB  1 
ATOM 1453 C CG  . LEU A 1 198 ? 160.927 143.232 170.877 1.00 75.38  ? 198 LEU R CG  1 
ATOM 1454 C CD1 . LEU A 1 198 ? 162.448 143.221 170.941 1.00 75.38  ? 198 LEU R CD1 1 
ATOM 1455 C CD2 . LEU A 1 198 ? 160.414 142.021 170.112 1.00 75.38  ? 198 LEU R CD2 1 
ATOM 1456 N N   . THR A 1 199 ? 159.357 145.909 174.731 1.00 74.20  ? 199 THR R N   1 
ATOM 1457 C CA  . THR A 1 199 ? 158.369 146.277 175.740 1.00 74.20  ? 199 THR R CA  1 
ATOM 1458 C C   . THR A 1 199 ? 157.455 147.344 175.150 1.00 74.20  ? 199 THR R C   1 
ATOM 1459 O O   . THR A 1 199 ? 157.890 148.475 174.906 1.00 74.20  ? 199 THR R O   1 
ATOM 1460 C CB  . THR A 1 199 ? 159.045 146.779 177.014 1.00 74.20  ? 199 THR R CB  1 
ATOM 1461 N N   . LEU A 1 200 ? 156.191 146.979 174.924 1.00 65.29  ? 200 LEU R N   1 
ATOM 1462 C CA  . LEU A 1 200 ? 155.183 147.883 174.367 1.00 65.29  ? 200 LEU R CA  1 
ATOM 1463 C C   . LEU A 1 200 ? 155.620 148.462 173.024 1.00 65.29  ? 200 LEU R C   1 
ATOM 1464 O O   . LEU A 1 200 ? 155.325 149.617 172.708 1.00 65.29  ? 200 LEU R O   1 
ATOM 1465 C CB  . LEU A 1 200 ? 154.840 149.008 175.348 1.00 65.29  ? 200 LEU R CB  1 
ATOM 1466 N N   . ILE A 1 201 ? 156.325 147.664 172.224 1.00 59.90  ? 201 ILE R N   1 
ATOM 1467 C CA  . ILE A 1 201 ? 156.797 148.083 170.911 1.00 59.90  ? 201 ILE R CA  1 
ATOM 1468 C C   . ILE A 1 201 ? 156.390 147.118 169.811 1.00 59.90  ? 201 ILE R C   1 
ATOM 1469 O O   . ILE A 1 201 ? 156.503 147.460 168.629 1.00 59.90  ? 201 ILE R O   1 
ATOM 1470 C CB  . ILE A 1 201 ? 158.327 148.288 170.905 1.00 59.90  ? 201 ILE R CB  1 
ATOM 1471 C CG1 . ILE A 1 201 ? 158.730 149.312 169.841 1.00 59.90  ? 201 ILE R CG1 1 
ATOM 1472 C CG2 . ILE A 1 201 ? 159.045 146.965 170.681 1.00 59.90  ? 201 ILE R CG2 1 
ATOM 1473 C CD1 . ILE A 1 201 ? 158.229 150.712 170.121 1.00 59.90  ? 201 ILE R CD1 1 
ATOM 1474 N N   . ARG A 1 202 ? 155.914 145.922 170.158 1.00 52.92  ? 202 ARG R N   1 
ATOM 1475 C CA  . ARG A 1 202 ? 155.467 144.951 169.173 1.00 52.92  ? 202 ARG R CA  1 
ATOM 1476 C C   . ARG A 1 202 ? 153.997 144.585 169.301 1.00 52.92  ? 202 ARG R C   1 
ATOM 1477 O O   . ARG A 1 202 ? 153.441 144.001 168.364 1.00 52.92  ? 202 ARG R O   1 
ATOM 1478 C CB  . ARG A 1 202 ? 156.312 143.670 169.260 1.00 52.92  ? 202 ARG R CB  1 
ATOM 1479 C CG  . ARG A 1 202 ? 157.595 143.721 168.447 1.00 52.92  ? 202 ARG R CG  1 
ATOM 1480 C CD  . ARG A 1 202 ? 157.312 143.961 166.973 1.00 52.92  ? 202 ARG R CD  1 
ATOM 1481 N NE  . ARG A 1 202 ? 158.402 144.671 166.315 1.00 52.92  ? 202 ARG R NE  1 
ATOM 1482 C CZ  . ARG A 1 202 ? 158.496 144.851 165.005 1.00 52.92  ? 202 ARG R CZ  1 
ATOM 1483 N NH1 . ARG A 1 202 ? 157.579 144.382 164.175 1.00 52.92  ? 202 ARG R NH1 1 
ATOM 1484 N NH2 . ARG A 1 202 ? 159.538 145.517 164.514 1.00 52.92  ? 202 ARG R NH2 1 
ATOM 1485 N N   . HIS A 1 203 ? 153.353 144.905 170.423 1.00 51.63  ? 203 HIS R N   1 
ATOM 1486 C CA  . HIS A 1 203 ? 151.928 144.649 170.588 1.00 51.63  ? 203 HIS R CA  1 
ATOM 1487 C C   . HIS A 1 203 ? 151.065 145.799 170.093 1.00 51.63  ? 203 HIS R C   1 
ATOM 1488 O O   . HIS A 1 203 ? 149.969 145.562 169.572 1.00 51.63  ? 203 HIS R O   1 
ATOM 1489 C CB  . HIS A 1 203 ? 151.610 144.368 172.060 1.00 51.63  ? 203 HIS R CB  1 
ATOM 1490 C CG  . HIS A 1 203 ? 150.147 144.232 172.347 1.00 51.63  ? 203 HIS R CG  1 
ATOM 1491 N ND1 . HIS A 1 203 ? 149.334 143.349 171.670 1.00 51.63  ? 203 HIS R ND1 1 
ATOM 1492 C CD2 . HIS A 1 203 ? 149.351 144.866 173.239 1.00 51.63  ? 203 HIS R CD2 1 
ATOM 1493 C CE1 . HIS A 1 203 ? 148.100 143.446 172.132 1.00 51.63  ? 203 HIS R CE1 1 
ATOM 1494 N NE2 . HIS A 1 203 ? 148.083 144.360 173.085 1.00 51.63  ? 203 HIS R NE2 1 
ATOM 1495 N N   . HIS A 1 204 ? 151.533 147.038 170.241 1.00 46.09  ? 204 HIS R N   1 
ATOM 1496 C CA  . HIS A 1 204 ? 150.785 148.201 169.782 1.00 46.09  ? 204 HIS R CA  1 
ATOM 1497 C C   . HIS A 1 204 ? 151.051 148.518 168.316 1.00 46.09  ? 204 HIS R C   1 
ATOM 1498 O O   . HIS A 1 204 ? 150.128 148.904 167.591 1.00 46.09  ? 204 HIS R O   1 
ATOM 1499 C CB  . HIS A 1 204 ? 151.124 149.419 170.646 1.00 46.09  ? 204 HIS R CB  1 
ATOM 1500 C CG  . HIS A 1 204 ? 150.273 149.548 171.870 1.00 46.09  ? 204 HIS R CG  1 
ATOM 1501 N ND1 . HIS A 1 204 ? 148.910 149.349 171.853 1.00 46.09  ? 204 HIS R ND1 1 
ATOM 1502 C CD2 . HIS A 1 204 ? 150.592 149.858 173.149 1.00 46.09  ? 204 HIS R CD2 1 
ATOM 1503 C CE1 . HIS A 1 204 ? 148.425 149.529 173.069 1.00 46.09  ? 204 HIS R CE1 1 
ATOM 1504 N NE2 . HIS A 1 204 ? 149.425 149.839 173.874 1.00 46.09  ? 204 HIS R NE2 1 
ATOM 1505 N N   . VAL A 1 205 ? 152.298 148.365 167.868 1.00 44.51  ? 205 VAL R N   1 
ATOM 1506 C CA  . VAL A 1 205 ? 152.635 148.666 166.479 1.00 44.51  ? 205 VAL R CA  1 
ATOM 1507 C C   . VAL A 1 205 ? 151.911 147.714 165.535 1.00 44.51  ? 205 VAL R C   1 
ATOM 1508 O O   . VAL A 1 205 ? 151.349 148.133 164.516 1.00 44.51  ? 205 VAL R O   1 
ATOM 1509 C CB  . VAL A 1 205 ? 154.160 148.616 166.274 1.00 44.51  ? 205 VAL R CB  1 
ATOM 1510 C CG1 . VAL A 1 205 ? 154.502 148.684 164.794 1.00 44.51  ? 205 VAL R CG1 1 
ATOM 1511 C CG2 . VAL A 1 205 ? 154.830 149.752 167.031 1.00 44.51  ? 205 VAL R CG2 1 
ATOM 1512 N N   . LEU A 1 206 ? 151.912 146.418 165.858 1.00 41.49  ? 206 LEU R N   1 
ATOM 1513 C CA  . LEU A 1 206 ? 151.232 145.443 165.011 1.00 41.49  ? 206 LEU R CA  1 
ATOM 1514 C C   . LEU A 1 206 ? 149.732 145.700 164.963 1.00 41.49  ? 206 LEU R C   1 
ATOM 1515 O O   . LEU A 1 206 ? 149.114 145.623 163.894 1.00 41.49  ? 206 LEU R O   1 
ATOM 1516 C CB  . LEU A 1 206 ? 151.518 144.025 165.507 1.00 41.49  ? 206 LEU R CB  1 
ATOM 1517 C CG  . LEU A 1 206 ? 151.256 142.899 164.505 1.00 41.49  ? 206 LEU R CG  1 
ATOM 1518 C CD1 . LEU A 1 206 ? 152.144 143.050 163.280 1.00 41.49  ? 206 LEU R CD1 1 
ATOM 1519 C CD2 . LEU A 1 206 ? 151.461 141.540 165.156 1.00 41.49  ? 206 LEU R CD2 1 
ATOM 1520 N N   . THR A 1 207 ? 149.127 146.004 166.115 1.00 39.87  ? 207 THR R N   1 
ATOM 1521 C CA  . THR A 1 207 ? 147.696 146.291 166.146 1.00 39.87  ? 207 THR R CA  1 
ATOM 1522 C C   . THR A 1 207 ? 147.366 147.538 165.335 1.00 39.87  ? 207 THR R C   1 
ATOM 1523 O O   . THR A 1 207 ? 146.381 147.559 164.587 1.00 39.87  ? 207 THR R O   1 
ATOM 1524 C CB  . THR A 1 207 ? 147.224 146.452 167.592 1.00 39.87  ? 207 THR R CB  1 
ATOM 1525 O OG1 . THR A 1 207 ? 147.507 145.254 168.325 1.00 39.87  ? 207 THR R OG1 1 
ATOM 1526 C CG2 . THR A 1 207 ? 145.728 146.726 167.639 1.00 39.87  ? 207 THR R CG2 1 
ATOM 1527 N N   . TRP A 1 208 ? 148.183 148.587 165.467 1.00 36.89  ? 208 TRP R N   1 
ATOM 1528 C CA  . TRP A 1 208 ? 147.943 149.810 164.708 1.00 36.89  ? 208 TRP R CA  1 
ATOM 1529 C C   . TRP A 1 208 ? 148.090 149.568 163.212 1.00 36.89  ? 208 TRP R C   1 
ATOM 1530 O O   . TRP A 1 208 ? 147.297 150.079 162.413 1.00 36.89  ? 208 TRP R O   1 
ATOM 1531 C CB  . TRP A 1 208 ? 148.898 150.910 165.169 1.00 36.89  ? 208 TRP R CB  1 
ATOM 1532 C CG  . TRP A 1 208 ? 148.361 151.734 166.296 1.00 36.89  ? 208 TRP R CG  1 
ATOM 1533 C CD1 . TRP A 1 208 ? 147.636 151.289 167.363 1.00 36.89  ? 208 TRP R CD1 1 
ATOM 1534 C CD2 . TRP A 1 208 ? 148.499 153.149 166.466 1.00 36.89  ? 208 TRP R CD2 1 
ATOM 1535 N NE1 . TRP A 1 208 ? 147.318 152.339 168.190 1.00 36.89  ? 208 TRP R NE1 1 
ATOM 1536 C CE2 . TRP A 1 208 ? 147.835 153.493 167.661 1.00 36.89  ? 208 TRP R CE2 1 
ATOM 1537 C CE3 . TRP A 1 208 ? 149.120 154.159 165.726 1.00 36.89  ? 208 TRP R CE3 1 
ATOM 1538 C CZ2 . TRP A 1 208 ? 147.776 154.802 168.132 1.00 36.89  ? 208 TRP R CZ2 1 
ATOM 1539 C CZ3 . TRP A 1 208 ? 149.059 155.459 166.195 1.00 36.89  ? 208 TRP R CZ3 1 
ATOM 1540 C CH2 . TRP A 1 208 ? 148.392 155.769 167.386 1.00 36.89  ? 208 TRP R CH2 1 
ATOM 1541 N N   . VAL A 1 209 ? 149.101 148.790 162.815 1.00 35.40  ? 209 VAL R N   1 
ATOM 1542 C CA  . VAL A 1 209 ? 149.298 148.472 161.403 1.00 35.40  ? 209 VAL R CA  1 
ATOM 1543 C C   . VAL A 1 209 ? 148.111 147.684 160.862 1.00 35.40  ? 209 VAL R C   1 
ATOM 1544 O O   . VAL A 1 209 ? 147.598 147.972 159.771 1.00 35.40  ? 209 VAL R O   1 
ATOM 1545 C CB  . VAL A 1 209 ? 150.624 147.711 161.217 1.00 35.40  ? 209 VAL R CB  1 
ATOM 1546 C CG1 . VAL A 1 209 ? 150.664 147.018 159.869 1.00 35.40  ? 209 VAL R CG1 1 
ATOM 1547 C CG2 . VAL A 1 209 ? 151.803 148.664 161.361 1.00 35.40  ? 209 VAL R CG2 1 
ATOM 1548 N N   . LYS A 1 210 ? 147.652 146.685 161.620 1.00 33.66  ? 210 LYS R N   1 
ATOM 1549 C CA  . LYS A 1 210 ? 146.497 145.902 161.195 1.00 33.66  ? 210 LYS R CA  1 
ATOM 1550 C C   . LYS A 1 210 ? 145.259 146.778 161.057 1.00 33.66  ? 210 LYS R C   1 
ATOM 1551 O O   . LYS A 1 210 ? 144.512 146.658 160.080 1.00 33.66  ? 210 LYS R O   1 
ATOM 1552 C CB  . LYS A 1 210 ? 146.244 144.766 162.186 1.00 33.66  ? 210 LYS R CB  1 
ATOM 1553 C CG  . LYS A 1 210 ? 145.026 143.916 161.865 1.00 33.66  ? 210 LYS R CG  1 
ATOM 1554 C CD  . LYS A 1 210 ? 144.955 142.686 162.757 1.00 33.66  ? 210 LYS R CD  1 
ATOM 1555 C CE  . LYS A 1 210 ? 144.617 143.058 164.192 1.00 33.66  ? 210 LYS R CE  1 
ATOM 1556 N NZ  . LYS A 1 210 ? 143.218 143.552 164.325 1.00 33.66  ? 210 LYS R NZ  1 
ATOM 1557 N N   . PHE A 1 211 ? 145.033 147.677 162.017 1.00 32.71  ? 211 PHE R N   1 
ATOM 1558 C CA  . PHE A 1 211 ? 143.868 148.554 161.951 1.00 32.71  ? 211 PHE R CA  1 
ATOM 1559 C C   . PHE A 1 211 ? 143.951 149.509 160.765 1.00 32.71  ? 211 PHE R C   1 
ATOM 1560 O O   . PHE A 1 211 ? 142.944 149.759 160.094 1.00 32.71  ? 211 PHE R O   1 
ATOM 1561 C CB  . PHE A 1 211 ? 143.723 149.331 163.258 1.00 32.71  ? 211 PHE R CB  1 
ATOM 1562 C CG  . PHE A 1 211 ? 142.572 150.297 163.265 1.00 32.71  ? 211 PHE R CG  1 
ATOM 1563 C CD1 . PHE A 1 211 ? 141.273 149.847 163.429 1.00 32.71  ? 211 PHE R CD1 1 
ATOM 1564 C CD2 . PHE A 1 211 ? 142.791 151.656 163.112 1.00 32.71  ? 211 PHE R CD2 1 
ATOM 1565 C CE1 . PHE A 1 211 ? 140.213 150.734 163.436 1.00 32.71  ? 211 PHE R CE1 1 
ATOM 1566 C CE2 . PHE A 1 211 ? 141.736 152.548 163.119 1.00 32.71  ? 211 PHE R CE2 1 
ATOM 1567 C CZ  . PHE A 1 211 ? 140.445 152.086 163.281 1.00 32.71  ? 211 PHE R CZ  1 
ATOM 1568 N N   . ILE A 1 212 ? 145.139 150.052 160.489 1.00 32.83  ? 212 ILE R N   1 
ATOM 1569 C CA  . ILE A 1 212 ? 145.243 151.079 159.459 1.00 32.83  ? 212 ILE R CA  1 
ATOM 1570 C C   . ILE A 1 212 ? 145.234 150.472 158.059 1.00 32.83  ? 212 ILE R C   1 
ATOM 1571 O O   . ILE A 1 212 ? 144.791 151.120 157.105 1.00 32.83  ? 212 ILE R O   1 
ATOM 1572 C CB  . ILE A 1 212 ? 146.495 151.947 159.688 1.00 32.83  ? 212 ILE R CB  1 
ATOM 1573 C CG1 . ILE A 1 212 ? 146.473 153.177 158.778 1.00 32.83  ? 212 ILE R CG1 1 
ATOM 1574 C CG2 . ILE A 1 212 ? 147.762 151.151 159.433 1.00 32.83  ? 212 ILE R CG2 1 
ATOM 1575 C CD1 . ILE A 1 212 ? 147.487 154.235 159.158 1.00 32.83  ? 212 ILE R CD1 1 
ATOM 1576 N N   . ILE A 1 213 ? 145.698 149.232 157.900 1.00 31.41  ? 213 ILE R N   1 
ATOM 1577 C CA  . ILE A 1 213 ? 145.744 148.634 156.570 1.00 31.41  ? 213 ILE R CA  1 
ATOM 1578 C C   . ILE A 1 213 ? 144.466 147.851 156.291 1.00 31.41  ? 213 ILE R C   1 
ATOM 1579 O O   . ILE A 1 213 ? 143.954 147.864 155.166 1.00 31.41  ? 213 ILE R O   1 
ATOM 1580 C CB  . ILE A 1 213 ? 146.994 147.751 156.399 1.00 31.41  ? 213 ILE R CB  1 
ATOM 1581 C CG1 . ILE A 1 213 ? 148.258 148.605 156.515 1.00 31.41  ? 213 ILE R CG1 1 
ATOM 1582 C CG2 . ILE A 1 213 ? 146.970 147.025 155.064 1.00 31.41  ? 213 ILE R CG2 1 
ATOM 1583 C CD1 . ILE A 1 213 ? 149.528 147.803 156.614 1.00 31.41  ? 213 ILE R CD1 1 
ATOM 1584 N N   . GLY A 1 214 ? 143.933 147.176 157.306 1.00 28.52  ? 214 GLY R N   1 
ATOM 1585 C CA  . GLY A 1 214 ? 142.769 146.338 157.101 1.00 28.52  ? 214 GLY R CA  1 
ATOM 1586 C C   . GLY A 1 214 ? 141.433 147.013 157.334 1.00 28.52  ? 214 GLY R C   1 
ATOM 1587 O O   . GLY A 1 214 ? 140.395 146.469 156.945 1.00 28.52  ? 214 GLY R O   1 
ATOM 1588 N N   . TYR A 1 215 ? 141.426 148.190 157.962 1.00 29.77  ? 215 TYR R N   1 
ATOM 1589 C CA  . TYR A 1 215 ? 140.154 148.862 158.203 1.00 29.77  ? 215 TYR R CA  1 
ATOM 1590 C C   . TYR A 1 215 ? 140.123 150.323 157.775 1.00 29.77  ? 215 TYR R C   1 
ATOM 1591 O O   . TYR A 1 215 ? 139.070 150.819 157.369 1.00 29.77  ? 215 TYR R O   1 
ATOM 1592 C CB  . TYR A 1 215 ? 139.770 148.781 159.679 1.00 29.77  ? 215 TYR R CB  1 
ATOM 1593 C CG  . TYR A 1 215 ? 138.303 149.052 159.904 1.00 29.77  ? 215 TYR R CG  1 
ATOM 1594 C CD1 . TYR A 1 215 ? 137.878 150.239 160.485 1.00 29.77  ? 215 TYR R CD1 1 
ATOM 1595 C CD2 . TYR A 1 215 ? 137.343 148.130 159.516 1.00 29.77  ? 215 TYR R CD2 1 
ATOM 1596 C CE1 . TYR A 1 215 ? 136.537 150.494 160.681 1.00 29.77  ? 215 TYR R CE1 1 
ATOM 1597 C CE2 . TYR A 1 215 ? 136.001 148.376 159.709 1.00 29.77  ? 215 TYR R CE2 1 
ATOM 1598 C CZ  . TYR A 1 215 ? 135.603 149.558 160.292 1.00 29.77  ? 215 TYR R CZ  1 
ATOM 1599 O OH  . TYR A 1 215 ? 134.265 149.805 160.484 1.00 29.77  ? 215 TYR R OH  1 
ATOM 1600 N N   . LEU A 1 216 ? 141.248 151.031 157.862 1.00 32.19  ? 216 LEU R N   1 
ATOM 1601 C CA  . LEU A 1 216 ? 141.201 152.476 157.657 1.00 32.19  ? 216 LEU R CA  1 
ATOM 1602 C C   . LEU A 1 216 ? 141.160 152.822 156.172 1.00 32.19  ? 216 LEU R C   1 
ATOM 1603 O O   . LEU A 1 216 ? 140.200 153.438 155.692 1.00 32.19  ? 216 LEU R O   1 
ATOM 1604 C CB  . LEU A 1 216 ? 142.397 153.143 158.344 1.00 32.19  ? 216 LEU R CB  1 
ATOM 1605 C CG  . LEU A 1 216 ? 142.336 154.661 158.531 1.00 32.19  ? 216 LEU R CG  1 
ATOM 1606 C CD1 . LEU A 1 216 ? 142.962 155.048 159.860 1.00 32.19  ? 216 LEU R CD1 1 
ATOM 1607 C CD2 . LEU A 1 216 ? 143.024 155.390 157.388 1.00 32.19  ? 216 LEU R CD2 1 
ATOM 1608 N N   . PHE A 1 217 ? 142.197 152.434 155.432 1.00 32.61  ? 217 PHE R N   1 
ATOM 1609 C CA  . PHE A 1 217 ? 142.192 152.649 153.988 1.00 32.61  ? 217 PHE R CA  1 
ATOM 1610 C C   . PHE A 1 217 ? 141.035 151.949 153.282 1.00 32.61  ? 217 PHE R C   1 
ATOM 1611 O O   . PHE A 1 217 ? 140.413 152.583 152.411 1.00 32.61  ? 217 PHE R O   1 
ATOM 1612 C CB  . PHE A 1 217 ? 143.541 152.217 153.396 1.00 32.61  ? 217 PHE R CB  1 
ATOM 1613 C CG  . PHE A 1 217 ? 144.588 153.295 153.418 1.00 32.61  ? 217 PHE R CG  1 
ATOM 1614 C CD1 . PHE A 1 217 ? 145.573 153.343 152.445 1.00 32.61  ? 217 PHE R CD1 1 
ATOM 1615 C CD2 . PHE A 1 217 ? 144.588 154.261 154.410 1.00 32.61  ? 217 PHE R CD2 1 
ATOM 1616 C CE1 . PHE A 1 217 ? 146.537 154.333 152.463 1.00 32.61  ? 217 PHE R CE1 1 
ATOM 1617 C CE2 . PHE A 1 217 ? 145.548 155.254 154.434 1.00 32.61  ? 217 PHE R CE2 1 
ATOM 1618 C CZ  . PHE A 1 217 ? 146.524 155.290 153.459 1.00 32.61  ? 217 PHE R CZ  1 
ATOM 1619 N N   . PRO A 1 218 ? 140.702 150.682 153.572 1.00 30.43  ? 218 PRO R N   1 
ATOM 1620 C CA  . PRO A 1 218 ? 139.542 150.075 152.894 1.00 30.43  ? 218 PRO R CA  1 
ATOM 1621 C C   . PRO A 1 218 ? 138.236 150.805 153.150 1.00 30.43  ? 218 PRO R C   1 
ATOM 1622 O O   . PRO A 1 218 ? 137.482 151.058 152.202 1.00 30.43  ? 218 PRO R O   1 
ATOM 1623 C CB  . PRO A 1 218 ? 139.515 148.652 153.467 1.00 30.43  ? 218 PRO R CB  1 
ATOM 1624 C CG  . PRO A 1 218 ? 140.919 148.385 153.854 1.00 30.43  ? 218 PRO R CG  1 
ATOM 1625 C CD  . PRO A 1 218 ? 141.414 149.688 154.396 1.00 30.43  ? 218 PRO R CD  1 
ATOM 1626 N N   . LEU A 1 219 ? 137.943 151.150 154.407 1.00 29.06  ? 219 LEU R N   1 
ATOM 1627 C CA  . LEU A 1 219 ? 136.700 151.854 154.707 1.00 29.06  ? 219 LEU R CA  1 
ATOM 1628 C C   . LEU A 1 219 ? 136.679 153.227 154.052 1.00 29.06  ? 219 LEU R C   1 
ATOM 1629 O O   . LEU A 1 219 ? 135.652 153.648 153.508 1.00 29.06  ? 219 LEU R O   1 
ATOM 1630 C CB  . LEU A 1 219 ? 136.508 151.979 156.218 1.00 29.06  ? 219 LEU R CB  1 
ATOM 1631 C CG  . LEU A 1 219 ? 135.238 152.687 156.693 1.00 29.06  ? 219 LEU R CG  1 
ATOM 1632 C CD1 . LEU A 1 219 ? 134.005 151.880 156.328 1.00 29.06  ? 219 LEU R CD1 1 
ATOM 1633 C CD2 . LEU A 1 219 ? 135.294 152.940 158.192 1.00 29.06  ? 219 LEU R CD2 1 
ATOM 1634 N N   . LEU A 1 220 ? 137.806 153.942 154.096 1.00 29.01  ? 220 LEU R N   1 
ATOM 1635 C CA  . LEU A 1 220 ? 137.869 155.254 153.462 1.00 29.01  ? 220 LEU R CA  1 
ATOM 1636 C C   . LEU A 1 220 ? 137.615 155.152 151.963 1.00 29.01  ? 220 LEU R C   1 
ATOM 1637 O O   . LEU A 1 220 ? 136.830 155.930 151.406 1.00 29.01  ? 220 LEU R O   1 
ATOM 1638 C CB  . LEU A 1 220 ? 139.226 155.902 153.734 1.00 29.01  ? 220 LEU R CB  1 
ATOM 1639 C CG  . LEU A 1 220 ? 139.433 157.316 153.189 1.00 29.01  ? 220 LEU R CG  1 
ATOM 1640 C CD1 . LEU A 1 220 ? 138.455 158.291 153.826 1.00 29.01  ? 220 LEU R CD1 1 
ATOM 1641 C CD2 . LEU A 1 220 ? 140.869 157.770 153.407 1.00 29.01  ? 220 LEU R CD2 1 
ATOM 1642 N N   . THR A 1 221 ? 138.257 154.187 151.299 1.00 29.22  ? 221 THR R N   1 
ATOM 1643 C CA  . THR A 1 221 ? 138.072 154.021 149.861 1.00 29.22  ? 221 THR R CA  1 
ATOM 1644 C C   . THR A 1 221 ? 136.629 153.663 149.532 1.00 29.22  ? 221 THR R C   1 
ATOM 1645 O O   . THR A 1 221 ? 136.017 154.261 148.637 1.00 29.22  ? 221 THR R O   1 
ATOM 1646 C CB  . THR A 1 221 ? 139.027 152.949 149.331 1.00 29.22  ? 221 THR R CB  1 
ATOM 1647 O OG1 . THR A 1 221 ? 140.376 153.426 149.411 1.00 29.22  ? 221 THR R OG1 1 
ATOM 1648 C CG2 . THR A 1 221 ? 138.700 152.607 147.885 1.00 29.22  ? 221 THR R CG2 1 
ATOM 1649 N N   . MET A 1 222 ? 136.065 152.689 150.252 1.00 27.98  ? 222 MET R N   1 
ATOM 1650 C CA  . MET A 1 222 ? 134.681 152.295 150.012 1.00 27.98  ? 222 MET R CA  1 
ATOM 1651 C C   . MET A 1 222 ? 133.745 153.482 150.179 1.00 27.98  ? 222 MET R C   1 
ATOM 1652 O O   . MET A 1 222 ? 132.901 153.750 149.315 1.00 27.98  ? 222 MET R O   1 
ATOM 1653 C CB  . MET A 1 222 ? 134.282 151.169 150.966 1.00 27.98  ? 222 MET R CB  1 
ATOM 1654 C CG  . MET A 1 222 ? 134.996 149.854 150.729 1.00 27.98  ? 222 MET R CG  1 
ATOM 1655 S SD  . MET A 1 222 ? 134.469 148.596 151.906 1.00 27.98  ? 222 MET R SD  1 
ATOM 1656 C CE  . MET A 1 222 ? 135.537 147.240 151.441 1.00 27.98  ? 222 MET R CE  1 
ATOM 1657 N N   . SER A 1 223 ? 133.900 154.222 151.279 1.00 29.98  ? 223 SER R N   1 
ATOM 1658 C CA  . SER A 1 223 ? 133.019 155.351 151.548 1.00 29.98  ? 223 SER R CA  1 
ATOM 1659 C C   . SER A 1 223 ? 133.122 156.401 150.451 1.00 29.98  ? 223 SER R C   1 
ATOM 1660 O O   . SER A 1 223 ? 132.107 156.808 149.876 1.00 29.98  ? 223 SER R O   1 
ATOM 1661 C CB  . SER A 1 223 ? 133.351 155.959 152.911 1.00 29.98  ? 223 SER R CB  1 
ATOM 1662 O OG  . SER A 1 223 ? 134.644 156.537 152.910 1.00 29.98  ? 223 SER R OG  1 
ATOM 1663 N N   . ILE A 1 224 ? 134.343 156.841 150.131 1.00 29.75  ? 224 ILE R N   1 
ATOM 1664 C CA  . ILE A 1 224 ? 134.493 157.929 149.166 1.00 29.75  ? 224 ILE R CA  1 
ATOM 1665 C C   . ILE A 1 224 ? 133.970 157.502 147.797 1.00 29.75  ? 224 ILE R C   1 
ATOM 1666 O O   . ILE A 1 224 ? 133.188 158.222 147.163 1.00 29.75  ? 224 ILE R O   1 
ATOM 1667 C CB  . ILE A 1 224 ? 135.953 158.420 149.103 1.00 29.75  ? 224 ILE R CB  1 
ATOM 1668 C CG1 . ILE A 1 224 ? 136.911 157.320 148.638 1.00 29.75  ? 224 ILE R CG1 1 
ATOM 1669 C CG2 . ILE A 1 224 ? 136.386 158.979 150.451 1.00 29.75  ? 224 ILE R CG2 1 
ATOM 1670 C CD1 . ILE A 1 224 ? 138.309 157.814 148.338 1.00 29.75  ? 224 ILE R CD1 1 
ATOM 1671 N N   . CYS A 1 225 ? 134.353 156.304 147.341 1.00 29.70  ? 225 CYS R N   1 
ATOM 1672 C CA  . CYS A 1 225 ? 133.939 155.862 146.014 1.00 29.70  ? 225 CYS R CA  1 
ATOM 1673 C C   . CYS A 1 225 ? 132.428 155.696 145.933 1.00 29.70  ? 225 CYS R C   1 
ATOM 1674 O O   . CYS A 1 225 ? 131.785 156.229 145.022 1.00 29.70  ? 225 CYS R O   1 
ATOM 1675 C CB  . CYS A 1 225 ? 134.650 154.560 145.643 1.00 29.70  ? 225 CYS R CB  1 
ATOM 1676 S SG  . CYS A 1 225 ? 136.455 154.670 145.618 1.00 29.70  ? 225 CYS R SG  1 
ATOM 1677 N N   . TYR A 1 226 ? 131.836 154.970 146.887 1.00 31.49  ? 226 TYR R N   1 
ATOM 1678 C CA  . TYR A 1 226 ? 130.404 154.704 146.818 1.00 31.49  ? 226 TYR R CA  1 
ATOM 1679 C C   . TYR A 1 226 ? 129.589 155.983 146.974 1.00 31.49  ? 226 TYR R C   1 
ATOM 1680 O O   . TYR A 1 226 ? 128.594 156.179 146.265 1.00 31.49  ? 226 TYR R O   1 
ATOM 1681 C CB  . TYR A 1 226 ? 130.016 153.673 147.877 1.00 31.49  ? 226 TYR R CB  1 
ATOM 1682 C CG  . TYR A 1 226 ? 130.306 152.249 147.455 1.00 31.49  ? 226 TYR R CG  1 
ATOM 1683 C CD1 . TYR A 1 226 ? 130.354 151.899 146.112 1.00 31.49  ? 226 TYR R CD1 1 
ATOM 1684 C CD2 . TYR A 1 226 ? 130.538 151.256 148.397 1.00 31.49  ? 226 TYR R CD2 1 
ATOM 1685 C CE1 . TYR A 1 226 ? 130.622 150.602 145.719 1.00 31.49  ? 226 TYR R CE1 1 
ATOM 1686 C CE2 . TYR A 1 226 ? 130.805 149.955 148.014 1.00 31.49  ? 226 TYR R CE2 1 
ATOM 1687 C CZ  . TYR A 1 226 ? 130.845 149.634 146.674 1.00 31.49  ? 226 TYR R CZ  1 
ATOM 1688 O OH  . TYR A 1 226 ? 131.111 148.341 146.287 1.00 31.49  ? 226 TYR R OH  1 
ATOM 1689 N N   . LEU A 1 227 ? 129.994 156.873 147.886 1.00 37.25  ? 227 LEU R N   1 
ATOM 1690 C CA  . LEU A 1 227 ? 129.244 158.107 148.086 1.00 37.25  ? 227 LEU R CA  1 
ATOM 1691 C C   . LEU A 1 227 ? 129.348 159.028 146.877 1.00 37.25  ? 227 LEU R C   1 
ATOM 1692 O O   . LEU A 1 227 ? 128.338 159.587 146.433 1.00 37.25  ? 227 LEU R O   1 
ATOM 1693 C CB  . LEU A 1 227 ? 129.724 158.817 149.352 1.00 37.25  ? 227 LEU R CB  1 
ATOM 1694 C CG  . LEU A 1 227 ? 128.935 158.521 150.631 1.00 37.25  ? 227 LEU R CG  1 
ATOM 1695 C CD1 . LEU A 1 227 ? 129.141 157.086 151.097 1.00 37.25  ? 227 LEU R CD1 1 
ATOM 1696 C CD2 . LEU A 1 227 ? 129.312 159.503 151.731 1.00 37.25  ? 227 LEU R CD2 1 
ATOM 1697 N N   . CYS A 1 228 ? 130.553 159.202 146.322 1.00 38.31  ? 228 CYS R N   1 
ATOM 1698 C CA  . CYS A 1 228 ? 130.685 160.050 145.143 1.00 38.31  ? 228 CYS R CA  1 
ATOM 1699 C C   . CYS A 1 228 ? 129.993 159.436 143.934 1.00 38.31  ? 228 CYS R C   1 
ATOM 1700 O O   . CYS A 1 228 ? 129.553 160.166 143.038 1.00 38.31  ? 228 CYS R O   1 
ATOM 1701 C CB  . CYS A 1 228 ? 132.160 160.309 144.839 1.00 38.31  ? 228 CYS R CB  1 
ATOM 1702 S SG  . CYS A 1 228 ? 132.997 158.958 143.983 1.00 38.31  ? 228 CYS R SG  1 
ATOM 1703 N N   . LEU A 1 229 ? 129.887 158.107 143.888 1.00 37.52  ? 229 LEU R N   1 
ATOM 1704 C CA  . LEU A 1 229 ? 129.195 157.458 142.782 1.00 37.52  ? 229 LEU R CA  1 
ATOM 1705 C C   . LEU A 1 229 ? 127.685 157.636 142.891 1.00 37.52  ? 229 LEU R C   1 
ATOM 1706 O O   . LEU A 1 229 ? 127.013 157.941 141.900 1.00 37.52  ? 229 LEU R O   1 
ATOM 1707 C CB  . LEU A 1 229 ? 129.563 155.977 142.742 1.00 37.52  ? 229 LEU R CB  1 
ATOM 1708 C CG  . LEU A 1 229 ? 128.964 155.177 141.591 1.00 37.52  ? 229 LEU R CG  1 
ATOM 1709 C CD1 . LEU A 1 229 ? 129.407 155.786 140.276 1.00 37.52  ? 229 LEU R CD1 1 
ATOM 1710 C CD2 . LEU A 1 229 ? 129.387 153.723 141.690 1.00 37.52  ? 229 LEU R CD2 1 
ATOM 1711 N N   . ILE A 1 230 ? 127.132 157.441 144.089 1.00 39.55  ? 230 ILE R N   1 
ATOM 1712 C CA  . ILE A 1 230 ? 125.683 157.513 144.253 1.00 39.55  ? 230 ILE R CA  1 
ATOM 1713 C C   . ILE A 1 230 ? 125.200 158.958 144.199 1.00 39.55  ? 230 ILE R C   1 
ATOM 1714 O O   . ILE A 1 230 ? 124.213 159.269 143.520 1.00 39.55  ? 230 ILE R O   1 
ATOM 1715 C CB  . ILE A 1 230 ? 125.260 156.822 145.561 1.00 39.55  ? 230 ILE R CB  1 
ATOM 1716 C CG1 . ILE A 1 230 ? 125.568 155.325 145.496 1.00 39.55  ? 230 ILE R CG1 1 
ATOM 1717 C CG2 . ILE A 1 230 ? 123.784 157.054 145.831 1.00 39.55  ? 230 ILE R CG2 1 
ATOM 1718 C CD1 . ILE A 1 230 ? 124.844 154.602 144.382 1.00 39.55  ? 230 ILE R CD1 1 
ATOM 1719 N N   . PHE A 1 231 ? 125.879 159.861 144.910 1.00 44.83  ? 231 PHE R N   1 
ATOM 1720 C CA  . PHE A 1 231 ? 125.400 161.236 145.019 1.00 44.83  ? 231 PHE R CA  1 
ATOM 1721 C C   . PHE A 1 231 ? 125.425 161.947 143.671 1.00 44.83  ? 231 PHE R C   1 
ATOM 1722 O O   . PHE A 1 231 ? 124.481 162.665 143.320 1.00 44.83  ? 231 PHE R O   1 
ATOM 1723 C CB  . PHE A 1 231 ? 126.236 162.001 146.047 1.00 44.83  ? 231 PHE R CB  1 
ATOM 1724 C CG  . PHE A 1 231 ? 126.040 161.531 147.462 1.00 44.83  ? 231 PHE R CG  1 
ATOM 1725 C CD1 . PHE A 1 231 ? 124.968 160.720 147.799 1.00 44.83  ? 231 PHE R CD1 1 
ATOM 1726 C CD2 . PHE A 1 231 ? 126.930 161.902 148.457 1.00 44.83  ? 231 PHE R CD2 1 
ATOM 1727 C CE1 . PHE A 1 231 ? 124.788 160.288 149.099 1.00 44.83  ? 231 PHE R CE1 1 
ATOM 1728 C CE2 . PHE A 1 231 ? 126.756 161.472 149.759 1.00 44.83  ? 231 PHE R CE2 1 
ATOM 1729 C CZ  . PHE A 1 231 ? 125.683 160.665 150.080 1.00 44.83  ? 231 PHE R CZ  1 
ATOM 1730 N N   . LYS A 1 232 ? 126.495 161.761 142.901 1.00 50.62  ? 232 LYS R N   1 
ATOM 1731 C CA  . LYS A 1 232 ? 126.645 162.462 141.633 1.00 50.62  ? 232 LYS R CA  1 
ATOM 1732 C C   . LYS A 1 232 ? 126.111 161.676 140.444 1.00 50.62  ? 232 LYS R C   1 
ATOM 1733 O O   . LYS A 1 232 ? 125.846 162.281 139.398 1.00 50.62  ? 232 LYS R O   1 
ATOM 1734 C CB  . LYS A 1 232 ? 128.119 162.807 141.393 1.00 50.62  ? 232 LYS R CB  1 
ATOM 1735 C CG  . LYS A 1 232 ? 128.572 164.086 142.078 1.00 50.62  ? 232 LYS R CG  1 
ATOM 1736 C CD  . LYS A 1 232 ? 129.071 163.810 143.488 1.00 50.62  ? 232 LYS R CD  1 
ATOM 1737 C CE  . LYS A 1 232 ? 129.903 164.967 144.017 1.00 50.62  ? 232 LYS R CE  1 
ATOM 1738 N NZ  . LYS A 1 232 ? 130.041 164.915 145.498 1.00 50.62  ? 232 LYS R NZ  1 
ATOM 1739 N N   . VAL A 1 233 ? 125.946 160.357 140.590 1.00 54.73  ? 233 VAL R N   1 
ATOM 1740 C CA  . VAL A 1 233 ? 125.470 159.427 139.562 1.00 54.73  ? 233 VAL R CA  1 
ATOM 1741 C C   . VAL A 1 233 ? 126.029 159.796 138.187 1.00 54.73  ? 233 VAL R C   1 
ATOM 1742 O O   . VAL A 1 233 ? 125.340 159.696 137.164 1.00 54.73  ? 233 VAL R O   1 
ATOM 1743 C CB  . VAL A 1 233 ? 123.923 159.345 139.577 1.00 54.73  ? 233 VAL R CB  1 
ATOM 1744 C CG1 . VAL A 1 233 ? 123.248 160.632 139.077 1.00 54.73  ? 233 VAL R CG1 1 
ATOM 1745 C CG2 . VAL A 1 233 ? 123.416 158.100 138.838 1.00 54.73  ? 233 VAL R CG2 1 
ATOM 1746 N N   . LYS A 1 234 ? 127.297 160.219 138.159 1.00 53.39  ? 234 LYS R N   1 
ATOM 1747 C CA  . LYS A 1 234 ? 128.022 160.557 136.930 1.00 53.39  ? 234 LYS R CA  1 
ATOM 1748 C C   . LYS A 1 234 ? 127.407 161.775 136.224 1.00 53.39  ? 234 LYS R C   1 
ATOM 1749 O O   . LYS A 1 234 ? 127.939 162.261 135.219 1.00 53.39  ? 234 LYS R O   1 
ATOM 1750 C CB  . LYS A 1 234 ? 128.100 159.331 135.999 1.00 53.39  ? 234 LYS R CB  1 
ATOM 1751 C CG  . LYS A 1 234 ? 128.659 159.547 134.597 1.00 53.39  ? 234 LYS R CG  1 
ATOM 1752 C CD  . LYS A 1 234 ? 130.161 159.778 134.626 1.00 53.39  ? 234 LYS R CD  1 
ATOM 1753 C CE  . LYS A 1 234 ? 130.670 160.270 133.280 1.00 53.39  ? 234 LYS R CE  1 
ATOM 1754 N NZ  . LYS A 1 234 ? 130.767 159.168 132.283 1.00 53.39  ? 234 LYS R NZ  1 
ATOM 1755 N N   . LYS A 1 235 ? 126.331 162.328 136.787 1.00 61.24  ? 235 LYS R N   1 
ATOM 1756 C CA  . LYS A 1 235 ? 125.565 163.404 136.157 1.00 61.24  ? 235 LYS R CA  1 
ATOM 1757 C C   . LYS A 1 235 ? 125.143 163.004 134.744 1.00 61.24  ? 235 LYS R C   1 
ATOM 1758 O O   . LYS A 1 235 ? 125.223 163.785 133.793 1.00 61.24  ? 235 LYS R O   1 
ATOM 1759 C CB  . LYS A 1 235 ? 126.353 164.716 136.151 1.00 61.24  ? 235 LYS R CB  1 
ATOM 1760 N N   . ARG A 1 236 ? 124.689 161.763 134.618 1.00 62.19  ? 236 ARG R N   1 
ATOM 1761 C CA  . ARG A 1 236 ? 124.346 161.172 133.331 1.00 62.19  ? 236 ARG R CA  1 
ATOM 1762 C C   . ARG A 1 236 ? 123.226 160.163 133.572 1.00 62.19  ? 236 ARG R C   1 
ATOM 1763 O O   . ARG A 1 236 ? 123.059 159.654 134.686 1.00 62.19  ? 236 ARG R O   1 
ATOM 1764 C CB  . ARG A 1 236 ? 125.600 160.563 132.687 1.00 62.19  ? 236 ARG R CB  1 
ATOM 1765 C CG  . ARG A 1 236 ? 125.372 159.428 131.703 1.00 62.19  ? 236 ARG R CG  1 
ATOM 1766 C CD  . ARG A 1 236 ? 126.661 159.072 130.984 1.00 62.19  ? 236 ARG R CD  1 
ATOM 1767 N NE  . ARG A 1 236 ? 126.960 160.004 129.903 1.00 62.19  ? 236 ARG R NE  1 
ATOM 1768 C CZ  . ARG A 1 236 ? 127.441 159.648 128.720 1.00 62.19  ? 236 ARG R CZ  1 
ATOM 1769 N NH1 . ARG A 1 236 ? 127.695 158.383 128.430 1.00 62.19  ? 236 ARG R NH1 1 
ATOM 1770 N NH2 . ARG A 1 236 ? 127.675 160.586 127.806 1.00 62.19  ? 236 ARG R NH2 1 
ATOM 1771 N N   . SER A 1 237 ? 122.456 159.870 132.529 1.00 72.78  ? 237 SER R N   1 
ATOM 1772 C CA  . SER A 1 237 ? 121.290 159.003 132.624 1.00 72.78  ? 237 SER R CA  1 
ATOM 1773 C C   . SER A 1 237 ? 121.677 157.573 132.247 1.00 72.78  ? 237 SER R C   1 
ATOM 1774 O O   . SER A 1 237 ? 122.856 157.248 132.081 1.00 72.78  ? 237 SER R O   1 
ATOM 1775 C CB  . SER A 1 237 ? 120.157 159.532 131.742 1.00 72.78  ? 237 SER R CB  1 
ATOM 1776 O OG  . SER A 1 237 ? 119.035 158.668 131.782 1.00 72.78  ? 237 SER R OG  1 
ATOM 1777 N N   . ILE A 1 238 ? 120.657 156.720 132.117 1.00 74.85  ? 238 ILE R N   1 
ATOM 1778 C CA  . ILE A 1 238 ? 120.795 155.292 131.833 1.00 74.85  ? 238 ILE R CA  1 
ATOM 1779 C C   . ILE A 1 238 ? 121.503 154.620 133.006 1.00 74.85  ? 238 ILE R C   1 
ATOM 1780 O O   . ILE A 1 238 ? 122.391 153.780 132.821 1.00 74.85  ? 238 ILE R O   1 
ATOM 1781 C CB  . ILE A 1 238 ? 121.524 155.032 130.497 1.00 74.85  ? 238 ILE R CB  1 
ATOM 1782 C CG1 . ILE A 1 238 ? 121.052 156.015 129.424 1.00 74.85  ? 238 ILE R CG1 1 
ATOM 1783 C CG2 . ILE A 1 238 ? 121.257 153.615 130.002 1.00 74.85  ? 238 ILE R CG2 1 
ATOM 1784 C CD1 . ILE A 1 238 ? 121.910 156.016 128.178 1.00 74.85  ? 238 ILE R CD1 1 
ATOM 1785 N N   . LEU A 1 239 ? 121.116 154.998 134.223 1.00 66.47  ? 239 LEU R N   1 
ATOM 1786 C CA  . LEU A 1 239 ? 121.527 154.302 135.439 1.00 66.47  ? 239 LEU R CA  1 
ATOM 1787 C C   . LEU A 1 239 ? 120.297 154.122 136.313 1.00 66.47  ? 239 LEU R C   1 
ATOM 1788 O O   . LEU A 1 239 ? 119.573 155.089 136.569 1.00 66.47  ? 239 LEU R O   1 
ATOM 1789 C CB  . LEU A 1 239 ? 122.619 155.061 136.204 1.00 66.47  ? 239 LEU R CB  1 
ATOM 1790 C CG  . LEU A 1 239 ? 124.080 155.006 135.739 1.00 66.47  ? 239 LEU R CG  1 
ATOM 1791 C CD1 . LEU A 1 239 ? 124.318 155.806 134.471 1.00 66.47  ? 239 LEU R CD1 1 
ATOM 1792 C CD2 . LEU A 1 239 ? 125.015 155.469 136.849 1.00 66.47  ? 239 LEU R CD2 1 
ATOM 1793 N N   . ILE A 1 240 ? 120.060 152.894 136.770 1.00 62.99  ? 240 ILE R N   1 
ATOM 1794 C CA  . ILE A 1 240 ? 118.904 152.602 137.609 1.00 62.99  ? 240 ILE R CA  1 
ATOM 1795 C C   . ILE A 1 240 ? 119.236 152.983 139.046 1.00 62.99  ? 240 ILE R C   1 
ATOM 1796 O O   . ILE A 1 240 ? 119.790 152.178 139.802 1.00 62.99  ? 240 ILE R O   1 
ATOM 1797 C CB  . ILE A 1 240 ? 118.485 151.123 137.509 1.00 62.99  ? 240 ILE R CB  1 
ATOM 1798 C CG1 . ILE A 1 240 ? 118.170 150.745 136.059 1.00 62.99  ? 240 ILE R CG1 1 
ATOM 1799 C CG2 . ILE A 1 240 ? 117.274 150.849 138.389 1.00 62.99  ? 240 ILE R CG2 1 
ATOM 1800 C CD1 . ILE A 1 240 ? 119.325 150.097 135.323 1.00 62.99  ? 240 ILE R CD1 1 
ATOM 1801 N N   . SER A 1 241 ? 118.905 154.218 139.429 1.00 57.84  ? 241 SER R N   1 
ATOM 1802 C CA  . SER A 1 241 ? 119.220 154.694 140.770 1.00 57.84  ? 241 SER R CA  1 
ATOM 1803 C C   . SER A 1 241 ? 118.316 154.086 141.835 1.00 57.84  ? 241 SER R C   1 
ATOM 1804 O O   . SER A 1 241 ? 118.626 154.196 143.026 1.00 57.84  ? 241 SER R O   1 
ATOM 1805 C CB  . SER A 1 241 ? 119.129 156.220 140.822 1.00 57.84  ? 241 SER R CB  1 
ATOM 1806 O OG  . SER A 1 241 ? 117.932 156.680 140.219 1.00 57.84  ? 241 SER R OG  1 
ATOM 1807 N N   . SER A 1 242 ? 117.207 153.460 141.437 1.00 52.86  ? 242 SER R N   1 
ATOM 1808 C CA  . SER A 1 242 ? 116.293 152.869 142.409 1.00 52.86  ? 242 SER R CA  1 
ATOM 1809 C C   . SER A 1 242 ? 116.968 151.743 143.184 1.00 52.86  ? 242 SER R C   1 
ATOM 1810 O O   . SER A 1 242 ? 117.120 151.814 144.408 1.00 52.86  ? 242 SER R O   1 
ATOM 1811 C CB  . SER A 1 242 ? 115.034 152.364 141.702 1.00 52.86  ? 242 SER R CB  1 
ATOM 1812 O OG  . SER A 1 242 ? 114.134 151.774 142.624 1.00 52.86  ? 242 SER R OG  1 
ATOM 1813 N N   . ARG A 1 243 ? 117.381 150.687 142.480 1.00 49.82  ? 243 ARG R N   1 
ATOM 1814 C CA  . ARG A 1 243 ? 118.019 149.558 143.145 1.00 49.82  ? 243 ARG R CA  1 
ATOM 1815 C C   . ARG A 1 243 ? 119.462 149.857 143.534 1.00 49.82  ? 243 ARG R C   1 
ATOM 1816 O O   . ARG A 1 243 ? 119.928 149.382 144.576 1.00 49.82  ? 243 ARG R O   1 
ATOM 1817 C CB  . ARG A 1 243 ? 117.972 148.318 142.247 1.00 49.82  ? 243 ARG R CB  1 
ATOM 1818 C CG  . ARG A 1 243 ? 118.740 147.132 142.809 1.00 49.82  ? 243 ARG R CG  1 
ATOM 1819 C CD  . ARG A 1 243 ? 120.014 146.866 142.025 1.00 49.82  ? 243 ARG R CD  1 
ATOM 1820 N NE  . ARG A 1 243 ? 120.869 145.902 142.707 1.00 49.82  ? 243 ARG R NE  1 
ATOM 1821 C CZ  . ARG A 1 243 ? 121.953 145.352 142.179 1.00 49.82  ? 243 ARG R CZ  1 
ATOM 1822 N NH1 . ARG A 1 243 ? 122.336 145.628 140.943 1.00 49.82  ? 243 ARG R NH1 1 
ATOM 1823 N NH2 . ARG A 1 243 ? 122.676 144.511 142.912 1.00 49.82  ? 243 ARG R NH2 1 
ATOM 1824 N N   . HIS A 1 244 ? 120.178 150.633 142.716 1.00 46.85  ? 244 HIS R N   1 
ATOM 1825 C CA  . HIS A 1 244 ? 121.606 150.841 142.939 1.00 46.85  ? 244 HIS R CA  1 
ATOM 1826 C C   . HIS A 1 244 ? 121.865 151.533 144.272 1.00 46.85  ? 244 HIS R C   1 
ATOM 1827 O O   . HIS A 1 244 ? 122.752 151.128 145.034 1.00 46.85  ? 244 HIS R O   1 
ATOM 1828 C CB  . HIS A 1 244 ? 122.198 151.652 141.786 1.00 46.85  ? 244 HIS R CB  1 
ATOM 1829 C CG  . HIS A 1 244 ? 123.694 151.683 141.771 1.00 46.85  ? 244 HIS R CG  1 
ATOM 1830 N ND1 . HIS A 1 244 ? 124.411 152.590 141.020 1.00 46.85  ? 244 HIS R ND1 1 
ATOM 1831 C CD2 . HIS A 1 244 ? 124.609 150.916 142.408 1.00 46.85  ? 244 HIS R CD2 1 
ATOM 1832 C CE1 . HIS A 1 244 ? 125.703 152.383 141.199 1.00 46.85  ? 244 HIS R CE1 1 
ATOM 1833 N NE2 . HIS A 1 244 ? 125.851 151.372 142.036 1.00 46.85  ? 244 HIS R NE2 1 
ATOM 1834 N N   . PHE A 1 245 ? 121.097 152.584 144.571 1.00 46.46  ? 245 PHE R N   1 
ATOM 1835 C CA  . PHE A 1 245 ? 121.290 153.317 145.819 1.00 46.46  ? 245 PHE R CA  1 
ATOM 1836 C C   . PHE A 1 245 ? 121.039 152.424 147.027 1.00 46.46  ? 245 PHE R C   1 
ATOM 1837 O O   . PHE A 1 245 ? 121.830 152.407 147.979 1.00 46.46  ? 245 PHE R O   1 
ATOM 1838 C CB  . PHE A 1 245 ? 120.372 154.540 145.852 1.00 46.46  ? 245 PHE R CB  1 
ATOM 1839 C CG  . PHE A 1 245 ? 120.239 155.164 147.213 1.00 46.46  ? 245 PHE R CG  1 
ATOM 1840 C CD1 . PHE A 1 245 ? 121.355 155.607 147.903 1.00 46.46  ? 245 PHE R CD1 1 
ATOM 1841 C CD2 . PHE A 1 245 ? 118.994 155.305 147.803 1.00 46.46  ? 245 PHE R CD2 1 
ATOM 1842 C CE1 . PHE A 1 245 ? 121.232 156.180 149.154 1.00 46.46  ? 245 PHE R CE1 1 
ATOM 1843 C CE2 . PHE A 1 245 ? 118.864 155.877 149.055 1.00 46.46  ? 245 PHE R CE2 1 
ATOM 1844 C CZ  . PHE A 1 245 ? 119.985 156.315 149.731 1.00 46.46  ? 245 PHE R CZ  1 
ATOM 1845 N N   . TRP A 1 246 ? 119.936 151.671 147.004 1.00 45.56  ? 246 TRP R N   1 
ATOM 1846 C CA  . TRP A 1 246 ? 119.619 150.794 148.124 1.00 45.56  ? 246 TRP R CA  1 
ATOM 1847 C C   . TRP A 1 246 ? 120.677 149.713 148.296 1.00 45.56  ? 246 TRP R C   1 
ATOM 1848 O O   . TRP A 1 246 ? 121.088 149.414 149.421 1.00 45.56  ? 246 TRP R O   1 
ATOM 1849 C CB  . TRP A 1 246 ? 118.237 150.169 147.931 1.00 45.56  ? 246 TRP R CB  1 
ATOM 1850 C CG  . TRP A 1 246 ? 117.118 151.042 148.408 1.00 45.56  ? 246 TRP R CG  1 
ATOM 1851 C CD1 . TRP A 1 246 ? 117.048 152.402 148.328 1.00 45.56  ? 246 TRP R CD1 1 
ATOM 1852 C CD2 . TRP A 1 246 ? 115.907 150.615 149.044 1.00 45.56  ? 246 TRP R CD2 1 
ATOM 1853 N NE1 . TRP A 1 246 ? 115.869 152.849 148.872 1.00 45.56  ? 246 TRP R NE1 1 
ATOM 1854 C CE2 . TRP A 1 246 ? 115.150 151.771 149.319 1.00 45.56  ? 246 TRP R CE2 1 
ATOM 1855 C CE3 . TRP A 1 246 ? 115.389 149.368 149.407 1.00 45.56  ? 246 TRP R CE3 1 
ATOM 1856 C CZ2 . TRP A 1 246 ? 113.904 151.718 149.940 1.00 45.56  ? 246 TRP R CZ2 1 
ATOM 1857 C CZ3 . TRP A 1 246 ? 114.152 149.317 150.023 1.00 45.56  ? 246 TRP R CZ3 1 
ATOM 1858 C CH2 . TRP A 1 246 ? 113.423 150.484 150.283 1.00 45.56  ? 246 TRP R CH2 1 
ATOM 1859 N N   . THR A 1 247 ? 121.135 149.121 147.191 1.00 41.93  ? 247 THR R N   1 
ATOM 1860 C CA  . THR A 1 247 ? 122.146 148.071 147.276 1.00 41.93  ? 247 THR R CA  1 
ATOM 1861 C C   . THR A 1 247 ? 123.456 148.614 147.836 1.00 41.93  ? 247 THR R C   1 
ATOM 1862 O O   . THR A 1 247 ? 124.088 147.982 148.691 1.00 41.93  ? 247 THR R O   1 
ATOM 1863 C CB  . THR A 1 247 ? 122.365 147.442 145.899 1.00 41.93  ? 247 THR R CB  1 
ATOM 1864 O OG1 . THR A 1 247 ? 121.169 146.770 145.484 1.00 41.93  ? 247 THR R OG1 1 
ATOM 1865 C CG2 . THR A 1 247 ? 123.510 146.441 145.942 1.00 41.93  ? 247 THR R CG2 1 
ATOM 1866 N N   . ILE A 1 248 ? 123.875 149.793 147.369 1.00 38.57  ? 248 ILE R N   1 
ATOM 1867 C CA  . ILE A 1 248 ? 125.115 150.387 147.860 1.00 38.57  ? 248 ILE R CA  1 
ATOM 1868 C C   . ILE A 1 248 ? 125.003 150.712 149.344 1.00 38.57  ? 248 ILE R C   1 
ATOM 1869 O O   . ILE A 1 248 ? 125.918 150.430 150.129 1.00 38.57  ? 248 ILE R O   1 
ATOM 1870 C CB  . ILE A 1 248 ? 125.476 151.633 147.030 1.00 38.57  ? 248 ILE R CB  1 
ATOM 1871 C CG1 . ILE A 1 248 ? 125.885 151.227 145.613 1.00 38.57  ? 248 ILE R CG1 1 
ATOM 1872 C CG2 . ILE A 1 248 ? 126.586 152.424 147.702 1.00 38.57  ? 248 ILE R CG2 1 
ATOM 1873 C CD1 . ILE A 1 248 ? 127.085 150.313 145.563 1.00 38.57  ? 248 ILE R CD1 1 
ATOM 1874 N N   . LEU A 1 249 ? 123.879 151.306 149.757 1.00 40.14  ? 249 LEU R N   1 
ATOM 1875 C CA  . LEU A 1 249 ? 123.704 151.635 151.167 1.00 40.14  ? 249 LEU R CA  1 
ATOM 1876 C C   . LEU A 1 249 ? 123.688 150.378 152.028 1.00 40.14  ? 249 LEU R C   1 
ATOM 1877 O O   . LEU A 1 249 ? 124.299 150.345 153.103 1.00 40.14  ? 249 LEU R O   1 
ATOM 1878 C CB  . LEU A 1 249 ? 122.420 152.441 151.362 1.00 40.14  ? 249 LEU R CB  1 
ATOM 1879 C CG  . LEU A 1 249 ? 122.316 153.243 152.662 1.00 40.14  ? 249 LEU R CG  1 
ATOM 1880 C CD1 . LEU A 1 249 ? 123.583 154.050 152.899 1.00 40.14  ? 249 LEU R CD1 1 
ATOM 1881 C CD2 . LEU A 1 249 ? 121.096 154.150 152.637 1.00 40.14  ? 249 LEU R CD2 1 
ATOM 1882 N N   . VAL A 1 250 ? 123.009 149.326 151.563 1.00 37.62  ? 250 VAL R N   1 
ATOM 1883 C CA  . VAL A 1 250 ? 122.935 148.083 152.325 1.00 37.62  ? 250 VAL R CA  1 
ATOM 1884 C C   . VAL A 1 250 ? 124.313 147.452 152.461 1.00 37.62  ? 250 VAL R C   1 
ATOM 1885 O O   . VAL A 1 250 ? 124.692 146.991 153.544 1.00 37.62  ? 250 VAL R O   1 
ATOM 1886 C CB  . VAL A 1 250 ? 121.927 147.116 151.676 1.00 37.62  ? 250 VAL R CB  1 
ATOM 1887 C CG1 . VAL A 1 250 ? 122.120 145.705 152.210 1.00 37.62  ? 250 VAL R CG1 1 
ATOM 1888 C CG2 . VAL A 1 250 ? 120.505 147.584 151.936 1.00 37.62  ? 250 VAL R CG2 1 
ATOM 1889 N N   . VAL A 1 251 ? 125.087 147.419 151.372 1.00 33.46  ? 251 VAL R N   1 
ATOM 1890 C CA  . VAL A 1 251 ? 126.401 146.789 151.453 1.00 33.46  ? 251 VAL R CA  1 
ATOM 1891 C C   . VAL A 1 251 ? 127.343 147.605 152.333 1.00 33.46  ? 251 VAL R C   1 
ATOM 1892 O O   . VAL A 1 251 ? 128.124 147.035 153.108 1.00 33.46  ? 251 VAL R O   1 
ATOM 1893 C CB  . VAL A 1 251 ? 126.980 146.543 150.043 1.00 33.46  ? 251 VAL R CB  1 
ATOM 1894 C CG1 . VAL A 1 251 ? 127.422 147.834 149.376 1.00 33.46  ? 251 VAL R CG1 1 
ATOM 1895 C CG2 . VAL A 1 251 ? 128.136 145.566 150.116 1.00 33.46  ? 251 VAL R CG2 1 
ATOM 1896 N N   . VAL A 1 252 ? 127.267 148.938 152.268 1.00 31.95  ? 252 VAL R N   1 
ATOM 1897 C CA  . VAL A 1 252 ? 128.100 149.768 153.134 1.00 31.95  ? 252 VAL R CA  1 
ATOM 1898 C C   . VAL A 1 252 ? 127.736 149.541 154.596 1.00 31.95  ? 252 VAL R C   1 
ATOM 1899 O O   . VAL A 1 252 ? 128.613 149.370 155.453 1.00 31.95  ? 252 VAL R O   1 
ATOM 1900 C CB  . VAL A 1 252 ? 127.974 151.251 152.740 1.00 31.95  ? 252 VAL R CB  1 
ATOM 1901 C CG1 . VAL A 1 252 ? 128.552 152.142 153.828 1.00 31.95  ? 252 VAL R CG1 1 
ATOM 1902 C CG2 . VAL A 1 252 ? 128.673 151.507 151.416 1.00 31.95  ? 252 VAL R CG2 1 
ATOM 1903 N N   . VAL A 1 253 ? 126.435 149.516 154.901 1.00 32.14  ? 253 VAL R N   1 
ATOM 1904 C CA  . VAL A 1 253 ? 125.997 149.303 156.277 1.00 32.14  ? 253 VAL R CA  1 
ATOM 1905 C C   . VAL A 1 253 ? 126.445 147.934 156.773 1.00 32.14  ? 253 VAL R C   1 
ATOM 1906 O O   . VAL A 1 253 ? 126.954 147.800 157.891 1.00 32.14  ? 253 VAL R O   1 
ATOM 1907 C CB  . VAL A 1 253 ? 124.470 149.477 156.384 1.00 32.14  ? 253 VAL R CB  1 
ATOM 1908 C CG1 . VAL A 1 253 ? 123.933 148.771 157.621 1.00 32.14  ? 253 VAL R CG1 1 
ATOM 1909 C CG2 . VAL A 1 253 ? 124.106 150.953 156.404 1.00 32.14  ? 253 VAL R CG2 1 
ATOM 1910 N N   . ALA A 1 254 ? 126.283 146.901 155.942 1.00 32.77  ? 254 ALA R N   1 
ATOM 1911 C CA  . ALA A 1 254 ? 126.679 145.556 156.342 1.00 32.77  ? 254 ALA R CA  1 
ATOM 1912 C C   . ALA A 1 254 ? 128.176 145.476 156.607 1.00 32.77  ? 254 ALA R C   1 
ATOM 1913 O O   . ALA A 1 254 ? 128.610 144.818 157.559 1.00 32.77  ? 254 ALA R O   1 
ATOM 1914 C CB  . ALA A 1 254 ? 126.269 144.546 155.271 1.00 32.77  ? 254 ALA R CB  1 
ATOM 1915 N N   . PHE A 1 255 ? 128.985 146.132 155.770 1.00 30.89  ? 255 PHE R N   1 
ATOM 1916 C CA  . PHE A 1 255 ? 130.425 146.134 156.006 1.00 30.89  ? 255 PHE R CA  1 
ATOM 1917 C C   . PHE A 1 255 ? 130.778 146.866 157.296 1.00 30.89  ? 255 PHE R C   1 
ATOM 1918 O O   . PHE A 1 255 ? 131.627 146.400 158.066 1.00 30.89  ? 255 PHE R O   1 
ATOM 1919 C CB  . PHE A 1 255 ? 131.154 146.760 154.818 1.00 30.89  ? 255 PHE R CB  1 
ATOM 1920 C CG  . PHE A 1 255 ? 132.632 146.932 155.036 1.00 30.89  ? 255 PHE R CG  1 
ATOM 1921 C CD1 . PHE A 1 255 ? 133.493 145.854 154.914 1.00 30.89  ? 255 PHE R CD1 1 
ATOM 1922 C CD2 . PHE A 1 255 ? 133.160 148.170 155.363 1.00 30.89  ? 255 PHE R CD2 1 
ATOM 1923 C CE1 . PHE A 1 255 ? 134.852 146.007 155.113 1.00 30.89  ? 255 PHE R CE1 1 
ATOM 1924 C CE2 . PHE A 1 255 ? 134.518 148.329 155.564 1.00 30.89  ? 255 PHE R CE2 1 
ATOM 1925 C CZ  . PHE A 1 255 ? 135.365 147.246 155.438 1.00 30.89  ? 255 PHE R CZ  1 
ATOM 1926 N N   . VAL A 1 256 ? 130.144 148.014 157.550 1.00 31.12  ? 256 VAL R N   1 
ATOM 1927 C CA  . VAL A 1 256 ? 130.547 148.840 158.686 1.00 31.12  ? 256 VAL R CA  1 
ATOM 1928 C C   . VAL A 1 256 ? 130.111 148.220 160.011 1.00 31.12  ? 256 VAL R C   1 
ATOM 1929 O O   . VAL A 1 256 ? 130.907 148.123 160.952 1.00 31.12  ? 256 VAL R O   1 
ATOM 1930 C CB  . VAL A 1 256 ? 130.002 150.271 158.529 1.00 31.12  ? 256 VAL R CB  1 
ATOM 1931 C CG1 . VAL A 1 256 ? 130.328 151.097 159.762 1.00 31.12  ? 256 VAL R CG1 1 
ATOM 1932 C CG2 . VAL A 1 256 ? 130.596 150.926 157.296 1.00 31.12  ? 256 VAL R CG2 1 
ATOM 1933 N N   . VAL A 1 257 ? 128.850 147.785 160.110 1.00 32.70  ? 257 VAL R N   1 
ATOM 1934 C CA  . VAL A 1 257 ? 128.279 147.447 161.416 1.00 32.70  ? 257 VAL R CA  1 
ATOM 1935 C C   . VAL A 1 257 ? 128.906 146.226 162.069 1.00 32.70  ? 257 VAL R C   1 
ATOM 1936 O O   . VAL A 1 257 ? 128.725 146.028 163.277 1.00 32.70  ? 257 VAL R O   1 
ATOM 1937 C CB  . VAL A 1 257 ? 126.758 147.208 161.337 1.00 32.70  ? 257 VAL R CB  1 
ATOM 1938 C CG1 . VAL A 1 257 ? 126.041 148.471 160.877 1.00 32.70  ? 257 VAL R CG1 1 
ATOM 1939 C CG2 . VAL A 1 257 ? 126.441 146.029 160.431 1.00 32.70  ? 257 VAL R CG2 1 
ATOM 1940 N N   . CYS A 1 258 ? 129.634 145.403 161.323 1.00 33.69  ? 258 CYS R N   1 
ATOM 1941 C CA  . CYS A 1 258 ? 130.203 144.182 161.883 1.00 33.69  ? 258 CYS R CA  1 
ATOM 1942 C C   . CYS A 1 258 ? 131.699 144.265 162.137 1.00 33.69  ? 258 CYS R C   1 
ATOM 1943 O O   . CYS A 1 258 ? 132.166 143.798 163.179 1.00 33.69  ? 258 CYS R O   1 
ATOM 1944 C CB  . CYS A 1 258 ? 129.912 142.994 160.959 1.00 33.69  ? 258 CYS R CB  1 
ATOM 1945 S SG  . CYS A 1 258 ? 128.199 142.885 160.395 1.00 33.69  ? 258 CYS R SG  1 
ATOM 1946 N N   . TRP A 1 259 ? 132.471 144.838 161.212 1.00 31.50  ? 259 TRP R N   1 
ATOM 1947 C CA  . TRP A 1 259 ? 133.913 144.936 161.411 1.00 31.50  ? 259 TRP R CA  1 
ATOM 1948 C C   . TRP A 1 259 ? 134.285 146.031 162.404 1.00 31.50  ? 259 TRP R C   1 
ATOM 1949 O O   . TRP A 1 259 ? 135.346 145.950 163.039 1.00 31.50  ? 259 TRP R O   1 
ATOM 1950 C CB  . TRP A 1 259 ? 134.615 145.182 160.075 1.00 31.50  ? 259 TRP R CB  1 
ATOM 1951 C CG  . TRP A 1 259 ? 134.469 144.057 159.096 1.00 31.50  ? 259 TRP R CG  1 
ATOM 1952 C CD1 . TRP A 1 259 ? 133.636 144.014 158.017 1.00 31.50  ? 259 TRP R CD1 1 
ATOM 1953 C CD2 . TRP A 1 259 ? 135.175 142.810 159.107 1.00 31.50  ? 259 TRP R CD2 1 
ATOM 1954 N NE1 . TRP A 1 259 ? 133.780 142.820 157.354 1.00 31.50  ? 259 TRP R NE1 1 
ATOM 1955 C CE2 . TRP A 1 259 ? 134.719 142.062 158.004 1.00 31.50  ? 259 TRP R CE2 1 
ATOM 1956 C CE3 . TRP A 1 259 ? 136.148 142.254 159.943 1.00 31.50  ? 259 TRP R CE3 1 
ATOM 1957 C CZ2 . TRP A 1 259 ? 135.203 140.789 157.714 1.00 31.50  ? 259 TRP R CZ2 1 
ATOM 1958 C CZ3 . TRP A 1 259 ? 136.626 140.990 159.654 1.00 31.50  ? 259 TRP R CZ3 1 
ATOM 1959 C CH2 . TRP A 1 259 ? 136.153 140.271 158.549 1.00 31.50  ? 259 TRP R CH2 1 
ATOM 1960 N N   . THR A 1 260 ? 133.444 147.058 162.541 1.00 31.82  ? 260 THR R N   1 
ATOM 1961 C CA  . THR A 1 260 ? 133.764 148.158 163.448 1.00 31.82  ? 260 THR R CA  1 
ATOM 1962 C C   . THR A 1 260 ? 133.911 147.709 164.897 1.00 31.82  ? 260 THR R C   1 
ATOM 1963 O O   . THR A 1 260 ? 134.923 148.069 165.523 1.00 31.82  ? 260 THR R O   1 
ATOM 1964 C CB  . THR A 1 260 ? 132.715 149.270 163.320 1.00 31.82  ? 260 THR R CB  1 
ATOM 1965 O OG1 . THR A 1 260 ? 132.674 149.741 161.967 1.00 31.82  ? 260 THR R OG1 1 
ATOM 1966 C CG2 . THR A 1 260 ? 133.054 150.431 164.244 1.00 31.82  ? 260 THR R CG2 1 
ATOM 1967 N N   . PRO A 1 261 ? 132.968 146.966 165.499 1.00 33.15  ? 261 PRO R N   1 
ATOM 1968 C CA  . PRO A 1 261 ? 133.193 146.534 166.890 1.00 33.15  ? 261 PRO R CA  1 
ATOM 1969 C C   . PRO A 1 261 ? 134.423 145.661 167.045 1.00 33.15  ? 261 PRO R C   1 
ATOM 1970 O O   . PRO A 1 261 ? 135.128 145.763 168.056 1.00 33.15  ? 261 PRO R O   1 
ATOM 1971 C CB  . PRO A 1 261 ? 131.903 145.775 167.236 1.00 33.15  ? 261 PRO R CB  1 
ATOM 1972 C CG  . PRO A 1 261 ? 131.346 145.358 165.930 1.00 33.15  ? 261 PRO R CG  1 
ATOM 1973 C CD  . PRO A 1 261 ? 131.675 146.474 164.990 1.00 33.15  ? 261 PRO R CD  1 
ATOM 1974 N N   . TYR A 1 262 ? 134.712 144.817 166.051 1.00 34.52  ? 262 TYR R N   1 
ATOM 1975 C CA  . TYR A 1 262 ? 135.906 143.982 166.116 1.00 34.52  ? 262 TYR R CA  1 
ATOM 1976 C C   . TYR A 1 262 ? 137.167 144.833 166.137 1.00 34.52  ? 262 TYR R C   1 
ATOM 1977 O O   . TYR A 1 262 ? 138.090 144.570 166.917 1.00 34.52  ? 262 TYR R O   1 
ATOM 1978 C CB  . TYR A 1 262 ? 135.931 143.010 164.937 1.00 34.52  ? 262 TYR R CB  1 
ATOM 1979 C CG  . TYR A 1 262 ? 137.192 142.181 164.854 1.00 34.52  ? 262 TYR R CG  1 
ATOM 1980 C CD1 . TYR A 1 262 ? 137.410 141.128 165.732 1.00 34.52  ? 262 TYR R CD1 1 
ATOM 1981 C CD2 . TYR A 1 262 ? 138.163 142.449 163.898 1.00 34.52  ? 262 TYR R CD2 1 
ATOM 1982 C CE1 . TYR A 1 262 ? 138.560 140.365 165.661 1.00 34.52  ? 262 TYR R CE1 1 
ATOM 1983 C CE2 . TYR A 1 262 ? 139.317 141.692 163.820 1.00 34.52  ? 262 TYR R CE2 1 
ATOM 1984 C CZ  . TYR A 1 262 ? 139.510 140.651 164.704 1.00 34.52  ? 262 TYR R CZ  1 
ATOM 1985 O OH  . TYR A 1 262 ? 140.656 139.894 164.631 1.00 34.52  ? 262 TYR R OH  1 
ATOM 1986 N N   . HIS A 1 263 ? 137.218 145.873 165.305 1.00 32.60  ? 263 HIS R N   1 
ATOM 1987 C CA  . HIS A 1 263 ? 138.418 146.700 165.269 1.00 32.60  ? 263 HIS R CA  1 
ATOM 1988 C C   . HIS A 1 263 ? 138.535 147.608 166.488 1.00 32.60  ? 263 HIS R C   1 
ATOM 1989 O O   . HIS A 1 263 ? 139.654 147.887 166.934 1.00 32.60  ? 263 HIS R O   1 
ATOM 1990 C CB  . HIS A 1 263 ? 138.457 147.513 163.976 1.00 32.60  ? 263 HIS R CB  1 
ATOM 1991 C CG  . HIS A 1 263 ? 138.845 146.704 162.778 1.00 32.60  ? 263 HIS R CG  1 
ATOM 1992 N ND1 . HIS A 1 263 ? 137.948 145.914 162.091 1.00 32.60  ? 263 HIS R ND1 1 
ATOM 1993 C CD2 . HIS A 1 263 ? 140.041 146.535 162.166 1.00 32.60  ? 263 HIS R CD2 1 
ATOM 1994 C CE1 . HIS A 1 263 ? 138.570 145.310 161.095 1.00 32.60  ? 263 HIS R CE1 1 
ATOM 1995 N NE2 . HIS A 1 263 ? 139.841 145.670 161.118 1.00 32.60  ? 263 HIS R NE2 1 
ATOM 1996 N N   . LEU A 1 264 ? 137.414 148.070 167.052 1.00 36.51  ? 264 LEU R N   1 
ATOM 1997 C CA  . LEU A 1 264 ? 137.511 148.814 168.307 1.00 36.51  ? 264 LEU R CA  1 
ATOM 1998 C C   . LEU A 1 264 ? 137.934 147.917 169.463 1.00 36.51  ? 264 LEU R C   1 
ATOM 1999 O O   . LEU A 1 264 ? 138.657 148.368 170.357 1.00 36.51  ? 264 LEU R O   1 
ATOM 2000 C CB  . LEU A 1 264 ? 136.198 149.526 168.647 1.00 36.51  ? 264 LEU R CB  1 
ATOM 2001 C CG  . LEU A 1 264 ? 135.358 150.190 167.556 1.00 36.51  ? 264 LEU R CG  1 
ATOM 2002 C CD1 . LEU A 1 264 ? 134.150 150.887 168.163 1.00 36.51  ? 264 LEU R CD1 1 
ATOM 2003 C CD2 . LEU A 1 264 ? 136.195 151.170 166.748 1.00 36.51  ? 264 LEU R CD2 1 
ATOM 2004 N N   . PHE A 1 265 ? 137.496 146.655 169.473 1.00 38.86  ? 265 PHE R N   1 
ATOM 2005 C CA  . PHE A 1 265 ? 137.985 145.723 170.484 1.00 38.86  ? 265 PHE R CA  1 
ATOM 2006 C C   . PHE A 1 265 ? 139.465 145.419 170.294 1.00 38.86  ? 265 PHE R C   1 
ATOM 2007 O O   . PHE A 1 265 ? 140.197 145.272 171.279 1.00 38.86  ? 265 PHE R O   1 
ATOM 2008 C CB  . PHE A 1 265 ? 137.165 144.434 170.455 1.00 38.86  ? 265 PHE R CB  1 
ATOM 2009 C CG  . PHE A 1 265 ? 135.822 144.555 171.119 1.00 38.86  ? 265 PHE R CG  1 
ATOM 2010 C CD1 . PHE A 1 265 ? 135.526 145.645 171.921 1.00 38.86  ? 265 PHE R CD1 1 
ATOM 2011 C CD2 . PHE A 1 265 ? 134.857 143.577 170.943 1.00 38.86  ? 265 PHE R CD2 1 
ATOM 2012 C CE1 . PHE A 1 265 ? 134.293 145.758 172.533 1.00 38.86  ? 265 PHE R CE1 1 
ATOM 2013 C CE2 . PHE A 1 265 ? 133.622 143.685 171.553 1.00 38.86  ? 265 PHE R CE2 1 
ATOM 2014 C CZ  . PHE A 1 265 ? 133.340 144.777 172.349 1.00 38.86  ? 265 PHE R CZ  1 
ATOM 2015 N N   . SER A 1 266 ? 139.919 145.311 169.043 1.00 38.66  ? 266 SER R N   1 
ATOM 2016 C CA  . SER A 1 266 ? 141.342 145.117 168.786 1.00 38.66  ? 266 SER R CA  1 
ATOM 2017 C C   . SER A 1 266 ? 142.156 146.315 169.261 1.00 38.66  ? 266 SER R C   1 
ATOM 2018 O O   . SER A 1 266 ? 143.225 146.150 169.861 1.00 38.66  ? 266 SER R O   1 
ATOM 2019 C CB  . SER A 1 266 ? 141.577 144.862 167.298 1.00 38.66  ? 266 SER R CB  1 
ATOM 2020 O OG  . SER A 1 266 ? 140.973 143.648 166.887 1.00 38.66  ? 266 SER R OG  1 
ATOM 2021 N N   . ILE A 1 267 ? 141.667 147.532 169.002 1.00 40.53  ? 267 ILE R N   1 
ATOM 2022 C CA  . ILE A 1 267 ? 142.351 148.734 169.478 1.00 40.53  ? 267 ILE R CA  1 
ATOM 2023 C C   . ILE A 1 267 ? 142.084 149.005 170.949 1.00 40.53  ? 267 ILE R C   1 
ATOM 2024 O O   . ILE A 1 267 ? 142.734 149.879 171.538 1.00 40.53  ? 267 ILE R O   1 
ATOM 2025 C CB  . ILE A 1 267 ? 141.946 149.957 168.632 1.00 40.53  ? 267 ILE R CB  1 
ATOM 2026 C CG1 . ILE A 1 267 ? 143.058 151.008 168.634 1.00 40.53  ? 267 ILE R CG1 1 
ATOM 2027 C CG2 . ILE A 1 267 ? 140.649 150.563 169.143 1.00 40.53  ? 267 ILE R CG2 1 
ATOM 2028 C CD1 . ILE A 1 267 ? 144.226 150.658 167.742 1.00 40.53  ? 267 ILE R CD1 1 
ATOM 2029 N N   . TRP A 1 268 ? 141.155 148.271 171.565 1.00 49.36  ? 268 TRP R N   1 
ATOM 2030 C CA  . TRP A 1 268 ? 140.845 148.434 172.980 1.00 49.36  ? 268 TRP R CA  1 
ATOM 2031 C C   . TRP A 1 268 ? 141.954 147.913 173.886 1.00 49.36  ? 268 TRP R C   1 
ATOM 2032 O O   . TRP A 1 268 ? 141.903 148.150 175.098 1.00 49.36  ? 268 TRP R O   1 
ATOM 2033 C CB  . TRP A 1 268 ? 139.526 147.725 173.302 1.00 49.36  ? 268 TRP R CB  1 
ATOM 2034 C CG  . TRP A 1 268 ? 139.016 147.947 174.695 1.00 49.36  ? 268 TRP R CG  1 
ATOM 2035 C CD1 . TRP A 1 268 ? 139.096 147.078 175.744 1.00 49.36  ? 268 TRP R CD1 1 
ATOM 2036 C CD2 . TRP A 1 268 ? 138.340 149.110 175.187 1.00 49.36  ? 268 TRP R CD2 1 
ATOM 2037 N NE1 . TRP A 1 268 ? 138.515 147.630 176.860 1.00 49.36  ? 268 TRP R NE1 1 
ATOM 2038 C CE2 . TRP A 1 268 ? 138.043 148.877 176.545 1.00 49.36  ? 268 TRP R CE2 1 
ATOM 2039 C CE3 . TRP A 1 268 ? 137.959 150.326 174.613 1.00 49.36  ? 268 TRP R CE3 1 
ATOM 2040 C CZ2 . TRP A 1 268 ? 137.384 149.814 177.336 1.00 49.36  ? 268 TRP R CZ2 1 
ATOM 2041 C CZ3 . TRP A 1 268 ? 137.304 151.256 175.400 1.00 49.36  ? 268 TRP R CZ3 1 
ATOM 2042 C CH2 . TRP A 1 268 ? 137.023 150.995 176.747 1.00 49.36  ? 268 TRP R CH2 1 
ATOM 2043 N N   . GLU A 1 269 ? 142.959 147.234 173.331 1.00 55.52  ? 269 GLU R N   1 
ATOM 2044 C CA  . GLU A 1 269 ? 144.015 146.605 174.124 1.00 55.52  ? 269 GLU R CA  1 
ATOM 2045 C C   . GLU A 1 269 ? 144.928 147.691 174.687 1.00 55.52  ? 269 GLU R C   1 
ATOM 2046 O O   . GLU A 1 269 ? 146.052 147.913 174.232 1.00 55.52  ? 269 GLU R O   1 
ATOM 2047 C CB  . GLU A 1 269 ? 144.795 145.605 173.275 1.00 55.52  ? 269 GLU R CB  1 
ATOM 2048 C CG  . GLU A 1 269 ? 143.976 144.461 172.652 1.00 55.52  ? 269 GLU R CG  1 
ATOM 2049 C CD  . GLU A 1 269 ? 143.351 143.497 173.660 1.00 55.52  ? 269 GLU R CD  1 
ATOM 2050 O OE1 . GLU A 1 269 ? 143.358 142.281 173.379 1.00 55.52  ? 269 GLU R OE1 1 
ATOM 2051 O OE2 . GLU A 1 269 ? 142.839 143.931 174.713 1.00 55.52  ? 269 GLU R OE2 1 
ATOM 2052 N N   . LEU A 1 270 ? 144.420 148.382 175.707 1.00 70.90  ? 270 LEU R N   1 
ATOM 2053 C CA  . LEU A 1 270 ? 145.162 149.414 176.420 1.00 70.90  ? 270 LEU R CA  1 
ATOM 2054 C C   . LEU A 1 270 ? 145.448 149.062 177.872 1.00 70.90  ? 270 LEU R C   1 
ATOM 2055 O O   . LEU A 1 270 ? 146.379 149.619 178.457 1.00 70.90  ? 270 LEU R O   1 
ATOM 2056 C CB  . LEU A 1 270 ? 144.406 150.750 176.340 1.00 70.90  ? 270 LEU R CB  1 
ATOM 2057 C CG  . LEU A 1 270 ? 142.980 150.865 176.894 1.00 70.90  ? 270 LEU R CG  1 
ATOM 2058 C CD1 . LEU A 1 270 ? 142.937 151.130 178.387 1.00 70.90  ? 270 LEU R CD1 1 
ATOM 2059 C CD2 . LEU A 1 270 ? 142.209 151.939 176.138 1.00 70.90  ? 270 LEU R CD2 1 
ATOM 2060 N N   . THR A 1 271 ? 144.653 148.166 178.463 1.00 81.80  ? 271 THR R N   1 
ATOM 2061 C CA  . THR A 1 271 ? 144.938 147.486 179.726 1.00 81.80  ? 271 THR R CA  1 
ATOM 2062 C C   . THR A 1 271 ? 144.919 148.399 180.949 1.00 81.80  ? 271 THR R C   1 
ATOM 2063 O O   . THR A 1 271 ? 145.030 147.912 182.079 1.00 81.80  ? 271 THR R O   1 
ATOM 2064 C CB  . THR A 1 271 ? 146.293 146.765 179.665 1.00 81.80  ? 271 THR R CB  1 
ATOM 2065 O OG1 . THR A 1 271 ? 147.358 147.723 179.726 1.00 81.80  ? 271 THR R OG1 1 
ATOM 2066 C CG2 . THR A 1 271 ? 146.421 145.942 178.389 1.00 81.80  ? 271 THR R CG2 1 
ATOM 2067 N N   . ILE A 1 272 ? 144.781 149.710 180.758 1.00 88.53  ? 272 ILE R N   1 
ATOM 2068 C CA  . ILE A 1 272 ? 144.682 150.609 181.902 1.00 88.53  ? 272 ILE R CA  1 
ATOM 2069 C C   . ILE A 1 272 ? 143.678 151.721 181.630 1.00 88.53  ? 272 ILE R C   1 
ATOM 2070 O O   . ILE A 1 272 ? 144.009 152.727 180.992 1.00 88.53  ? 272 ILE R O   1 
ATOM 2071 C CB  . ILE A 1 272 ? 146.060 151.196 182.261 1.00 88.53  ? 272 ILE R CB  1 
ATOM 2072 N N   . HIS A 1 273 ? 142.449 151.555 182.117 1.00 103.26 ? 273 HIS R N   1 
ATOM 2073 C CA  . HIS A 1 273 ? 141.471 152.638 182.125 1.00 103.26 ? 273 HIS R CA  1 
ATOM 2074 C C   . HIS A 1 273 ? 141.052 153.000 183.542 1.00 103.26 ? 273 HIS R C   1 
ATOM 2075 O O   . HIS A 1 273 ? 141.219 154.151 183.957 1.00 103.26 ? 273 HIS R O   1 
ATOM 2076 C CB  . HIS A 1 273 ? 140.250 152.252 181.278 1.00 103.26 ? 273 HIS R CB  1 
ATOM 2077 N N   . HIS A 1 274 ? 140.511 152.045 184.299 1.00 109.44 ? 274 HIS R N   1 
ATOM 2078 C CA  . HIS A 1 274 ? 140.243 152.231 185.723 1.00 109.44 ? 274 HIS R CA  1 
ATOM 2079 C C   . HIS A 1 274 ? 140.643 151.043 186.582 1.00 109.44 ? 274 HIS R C   1 
ATOM 2080 O O   . HIS A 1 274 ? 140.871 151.228 187.782 1.00 109.44 ? 274 HIS R O   1 
ATOM 2081 C CB  . HIS A 1 274 ? 138.758 152.534 185.957 1.00 109.44 ? 274 HIS R CB  1 
ATOM 2082 N N   . ASN A 1 275 ? 140.737 149.841 186.027 1.00 108.33 ? 275 ASN R N   1 
ATOM 2083 C CA  . ASN A 1 275 ? 141.129 148.648 186.766 1.00 108.33 ? 275 ASN R CA  1 
ATOM 2084 C C   . ASN A 1 275 ? 141.824 147.707 185.786 1.00 108.33 ? 275 ASN R C   1 
ATOM 2085 O O   . ASN A 1 275 ? 142.273 148.131 184.716 1.00 108.33 ? 275 ASN R O   1 
ATOM 2086 C CB  . ASN A 1 275 ? 139.911 148.024 187.472 1.00 108.33 ? 275 ASN R CB  1 
ATOM 2087 C CG  . ASN A 1 275 ? 138.838 147.563 186.502 1.00 108.33 ? 275 ASN R CG  1 
ATOM 2088 O OD1 . ASN A 1 275 ? 139.055 146.660 185.695 1.00 108.33 ? 275 ASN R OD1 1 
ATOM 2089 N ND2 . ASN A 1 275 ? 137.667 148.184 186.584 1.00 108.33 ? 275 ASN R ND2 1 
ATOM 2090 N N   . SER A 1 276 ? 141.925 146.428 186.156 1.00 105.49 ? 276 SER R N   1 
ATOM 2091 C CA  . SER A 1 276 ? 142.608 145.457 185.305 1.00 105.49 ? 276 SER R CA  1 
ATOM 2092 C C   . SER A 1 276 ? 141.950 145.363 183.934 1.00 105.49 ? 276 SER R C   1 
ATOM 2093 O O   . SER A 1 276 ? 142.630 145.393 182.902 1.00 105.49 ? 276 SER R O   1 
ATOM 2094 C CB  . SER A 1 276 ? 142.629 144.089 185.988 1.00 105.49 ? 276 SER R CB  1 
ATOM 2095 O OG  . SER A 1 276 ? 141.327 143.533 186.052 1.00 105.49 ? 276 SER R OG  1 
ATOM 2096 N N   . TYR A 1 277 ? 140.622 145.250 183.902 1.00 101.95 ? 277 TYR R N   1 
ATOM 2097 C CA  . TYR A 1 277 ? 139.875 145.155 182.653 1.00 101.95 ? 277 TYR R CA  1 
ATOM 2098 C C   . TYR A 1 277 ? 138.977 146.364 182.423 1.00 101.95 ? 277 TYR R C   1 
ATOM 2099 O O   . TYR A 1 277 ? 139.055 146.997 181.365 1.00 101.95 ? 277 TYR R O   1 
ATOM 2100 C CB  . TYR A 1 277 ? 139.047 143.861 182.631 1.00 101.95 ? 277 TYR R CB  1 
ATOM 2101 C CG  . TYR A 1 277 ? 139.818 142.633 182.194 1.00 101.95 ? 277 TYR R CG  1 
ATOM 2102 C CD1 . TYR A 1 277 ? 141.205 142.647 182.112 1.00 101.95 ? 277 TYR R CD1 1 
ATOM 2103 C CD2 . TYR A 1 277 ? 139.156 141.461 181.858 1.00 101.95 ? 277 TYR R CD2 1 
ATOM 2104 C CE1 . TYR A 1 277 ? 141.909 141.528 181.709 1.00 101.95 ? 277 TYR R CE1 1 
ATOM 2105 C CE2 . TYR A 1 277 ? 139.851 140.336 181.454 1.00 101.95 ? 277 TYR R CE2 1 
ATOM 2106 C CZ  . TYR A 1 277 ? 141.227 140.375 181.382 1.00 101.95 ? 277 TYR R CZ  1 
ATOM 2107 O OH  . TYR A 1 277 ? 141.921 139.257 180.980 1.00 101.95 ? 277 TYR R OH  1 
ATOM 2108 N N   . SER A 1 278 ? 138.103 146.684 183.382 1.00 109.68 ? 278 SER R N   1 
ATOM 2109 C CA  . SER A 1 278 ? 137.192 147.825 183.306 1.00 109.68 ? 278 SER R CA  1 
ATOM 2110 C C   . SER A 1 278 ? 136.203 147.697 182.152 1.00 109.68 ? 278 SER R C   1 
ATOM 2111 O O   . SER A 1 278 ? 135.441 148.629 181.878 1.00 109.68 ? 278 SER R O   1 
ATOM 2112 C CB  . SER A 1 278 ? 137.975 149.138 183.191 1.00 109.68 ? 278 SER R CB  1 
ATOM 2113 O OG  . SER A 1 278 ? 137.099 150.246 183.073 1.00 109.68 ? 278 SER R OG  1 
ATOM 2114 N N   . HIS A 1 279 ? 136.204 146.550 181.472 1.00 101.27 ? 279 HIS R N   1 
ATOM 2115 C CA  . HIS A 1 279 ? 135.256 146.305 180.397 1.00 101.27 ? 279 HIS R CA  1 
ATOM 2116 C C   . HIS A 1 279 ? 134.671 144.901 180.415 1.00 101.27 ? 279 HIS R C   1 
ATOM 2117 O O   . HIS A 1 279 ? 133.826 144.598 179.567 1.00 101.27 ? 279 HIS R O   1 
ATOM 2118 C CB  . HIS A 1 279 ? 135.917 146.559 179.031 1.00 101.27 ? 279 HIS R CB  1 
ATOM 2119 N N   . HIS A 1 280 ? 135.078 144.048 181.358 1.00 93.63  ? 280 HIS R N   1 
ATOM 2120 C CA  . HIS A 1 280 ? 134.570 142.680 181.479 1.00 93.63  ? 280 HIS R CA  1 
ATOM 2121 C C   . HIS A 1 280 ? 134.716 141.939 180.147 1.00 93.63  ? 280 HIS R C   1 
ATOM 2122 O O   . HIS A 1 280 ? 133.813 141.239 179.684 1.00 93.63  ? 280 HIS R O   1 
ATOM 2123 C CB  . HIS A 1 280 ? 133.121 142.690 181.988 1.00 93.63  ? 280 HIS R CB  1 
ATOM 2124 C CG  . HIS A 1 280 ? 132.521 141.332 182.197 1.00 93.63  ? 280 HIS R CG  1 
ATOM 2125 N ND1 . HIS A 1 280 ? 132.871 140.521 183.255 1.00 93.63  ? 280 HIS R ND1 1 
ATOM 2126 C CD2 . HIS A 1 280 ? 131.562 140.665 181.514 1.00 93.63  ? 280 HIS R CD2 1 
ATOM 2127 C CE1 . HIS A 1 280 ? 132.173 139.401 183.200 1.00 93.63  ? 280 HIS R CE1 1 
ATOM 2128 N NE2 . HIS A 1 280 ? 131.370 139.464 182.154 1.00 93.63  ? 280 HIS R NE2 1 
ATOM 2129 N N   . VAL A 1 281 ? 135.879 142.116 179.512 1.00 87.16  ? 281 VAL R N   1 
ATOM 2130 C CA  . VAL A 1 281 ? 136.148 141.495 178.219 1.00 87.16  ? 281 VAL R CA  1 
ATOM 2131 C C   . VAL A 1 281 ? 136.361 139.995 178.317 1.00 87.16  ? 281 VAL R C   1 
ATOM 2132 O O   . VAL A 1 281 ? 136.365 139.313 177.286 1.00 87.16  ? 281 VAL R O   1 
ATOM 2133 C CB  . VAL A 1 281 ? 137.379 142.130 177.538 1.00 87.16  ? 281 VAL R CB  1 
ATOM 2134 C CG1 . VAL A 1 281 ? 137.141 143.607 177.263 1.00 87.16  ? 281 VAL R CG1 1 
ATOM 2135 C CG2 . VAL A 1 281 ? 138.628 141.928 178.382 1.00 87.16  ? 281 VAL R CG2 1 
ATOM 2136 N N   . MET A 1 282 ? 136.550 139.460 179.526 1.00 85.70  ? 282 MET R N   1 
ATOM 2137 C CA  . MET A 1 282 ? 136.736 138.021 179.674 1.00 85.70  ? 282 MET R CA  1 
ATOM 2138 C C   . MET A 1 282 ? 135.496 137.239 179.266 1.00 85.70  ? 282 MET R C   1 
ATOM 2139 O O   . MET A 1 282 ? 135.593 136.036 179.006 1.00 85.70  ? 282 MET R O   1 
ATOM 2140 C CB  . MET A 1 282 ? 137.115 137.679 181.117 1.00 85.70  ? 282 MET R CB  1 
ATOM 2141 C CG  . MET A 1 282 ? 136.040 137.990 182.142 1.00 85.70  ? 282 MET R CG  1 
ATOM 2142 S SD  . MET A 1 282 ? 136.573 137.667 183.834 1.00 85.70  ? 282 MET R SD  1 
ATOM 2143 C CE  . MET A 1 282 ? 137.702 139.030 184.107 1.00 85.70  ? 282 MET R CE  1 
ATOM 2144 N N   . GLN A 1 283 ? 134.343 137.896 179.187 1.00 73.03  ? 283 GLN R N   1 
ATOM 2145 C CA  . GLN A 1 283 ? 133.113 137.251 178.754 1.00 73.03  ? 283 GLN R CA  1 
ATOM 2146 C C   . GLN A 1 283 ? 133.095 137.172 177.228 1.00 73.03  ? 283 GLN R C   1 
ATOM 2147 O O   . GLN A 1 283 ? 134.098 137.424 176.553 1.00 73.03  ? 283 GLN R O   1 
ATOM 2148 C CB  . GLN A 1 283 ? 131.904 137.998 179.308 1.00 73.03  ? 283 GLN R CB  1 
ATOM 2149 N N   . ALA A 1 284 ? 131.941 136.828 176.660 1.00 58.14  ? 284 ALA R N   1 
ATOM 2150 C CA  . ALA A 1 284 ? 131.829 136.578 175.232 1.00 58.14  ? 284 ALA R CA  1 
ATOM 2151 C C   . ALA A 1 284 ? 131.526 137.837 174.423 1.00 58.14  ? 284 ALA R C   1 
ATOM 2152 O O   . ALA A 1 284 ? 130.927 137.736 173.349 1.00 58.14  ? 284 ALA R O   1 
ATOM 2153 C CB  . ALA A 1 284 ? 130.765 135.510 174.968 1.00 58.14  ? 284 ALA R CB  1 
ATOM 2154 N N   . GLY A 1 285 ? 131.927 139.017 174.902 1.00 51.31  ? 285 GLY R N   1 
ATOM 2155 C CA  . GLY A 1 285 ? 131.726 140.224 174.110 1.00 51.31  ? 285 GLY R CA  1 
ATOM 2156 C C   . GLY A 1 285 ? 132.613 140.272 172.879 1.00 51.31  ? 285 GLY R C   1 
ATOM 2157 O O   . GLY A 1 285 ? 132.141 140.506 171.760 1.00 51.31  ? 285 GLY R O   1 
ATOM 2158 N N   . ILE A 1 286 ? 133.919 140.061 173.069 1.00 45.67  ? 286 ILE R N   1 
ATOM 2159 C CA  . ILE A 1 286 ? 134.830 139.979 171.925 1.00 45.67  ? 286 ILE R CA  1 
ATOM 2160 C C   . ILE A 1 286 ? 134.507 138.784 171.040 1.00 45.67  ? 286 ILE R C   1 
ATOM 2161 O O   . ILE A 1 286 ? 134.542 138.927 169.809 1.00 45.67  ? 286 ILE R O   1 
ATOM 2162 C CB  . ILE A 1 286 ? 136.287 140.009 172.404 1.00 45.67  ? 286 ILE R CB  1 
ATOM 2163 C CG1 . ILE A 1 286 ? 136.568 141.305 173.167 1.00 45.67  ? 286 ILE R CG1 1 
ATOM 2164 C CG2 . ILE A 1 286 ? 137.238 139.893 171.228 1.00 45.67  ? 286 ILE R CG2 1 
ATOM 2165 C CD1 . ILE A 1 286 ? 137.972 141.388 173.731 1.00 45.67  ? 286 ILE R CD1 1 
ATOM 2166 N N   . PRO A 1 287 ? 134.223 137.584 171.566 1.00 43.40  ? 287 PRO R N   1 
ATOM 2167 C CA  . PRO A 1 287 ? 133.735 136.511 170.684 1.00 43.40  ? 287 PRO R CA  1 
ATOM 2168 C C   . PRO A 1 287 ? 132.449 136.859 169.951 1.00 43.40  ? 287 PRO R C   1 
ATOM 2169 O O   . PRO A 1 287 ? 132.264 136.419 168.812 1.00 43.40  ? 287 PRO R O   1 
ATOM 2170 C CB  . PRO A 1 287 ? 133.539 135.333 171.647 1.00 43.40  ? 287 PRO R CB  1 
ATOM 2171 C CG  . PRO A 1 287 ? 134.518 135.582 172.732 1.00 43.40  ? 287 PRO R CG  1 
ATOM 2172 C CD  . PRO A 1 287 ? 134.547 137.071 172.911 1.00 43.40  ? 287 PRO R CD  1 
ATOM 2173 N N   . LEU A 1 288 ? 131.551 137.633 170.565 1.00 43.63  ? 288 LEU R N   1 
ATOM 2174 C CA  . LEU A 1 288 ? 130.341 138.062 169.868 1.00 43.63  ? 288 LEU R CA  1 
ATOM 2175 C C   . LEU A 1 288 ? 130.673 139.000 168.715 1.00 43.63  ? 288 LEU R C   1 
ATOM 2176 O O   . LEU A 1 288 ? 130.082 138.902 167.633 1.00 43.63  ? 288 LEU R O   1 
ATOM 2177 C CB  . LEU A 1 288 ? 129.386 138.739 170.851 1.00 43.63  ? 288 LEU R CB  1 
ATOM 2178 C CG  . LEU A 1 288 ? 128.053 139.227 170.284 1.00 43.63  ? 288 LEU R CG  1 
ATOM 2179 C CD1 . LEU A 1 288 ? 127.232 138.056 169.772 1.00 43.63  ? 288 LEU R CD1 1 
ATOM 2180 C CD2 . LEU A 1 288 ? 127.284 140.019 171.331 1.00 43.63  ? 288 LEU R CD2 1 
ATOM 2181 N N   . SER A 1 289 ? 131.614 139.919 168.928 1.00 39.30  ? 289 SER R N   1 
ATOM 2182 C CA  . SER A 1 289 ? 132.045 140.794 167.840 1.00 39.30  ? 289 SER R CA  1 
ATOM 2183 C C   . SER A 1 289 ? 132.723 139.994 166.731 1.00 39.30  ? 289 SER R C   1 
ATOM 2184 O O   . SER A 1 289 ? 132.540 140.280 165.539 1.00 39.30  ? 289 SER R O   1 
ATOM 2185 C CB  . SER A 1 289 ? 132.977 141.876 168.378 1.00 39.30  ? 289 SER R CB  1 
ATOM 2186 O OG  . SER A 1 289 ? 133.294 142.815 167.370 1.00 39.30  ? 289 SER R OG  1 
ATOM 2187 N N   . THR A 1 290 ? 133.507 138.983 167.108 1.00 38.21  ? 290 THR R N   1 
ATOM 2188 C CA  . THR A 1 290 ? 134.118 138.103 166.118 1.00 38.21  ? 290 THR R CA  1 
ATOM 2189 C C   . THR A 1 290 ? 133.055 137.344 165.330 1.00 38.21  ? 290 THR R C   1 
ATOM 2190 O O   . THR A 1 290 ? 133.180 137.160 164.114 1.00 38.21  ? 290 THR R O   1 
ATOM 2191 C CB  . THR A 1 290 ? 135.077 137.133 166.808 1.00 38.21  ? 290 THR R CB  1 
ATOM 2192 O OG1 . THR A 1 290 ? 136.027 137.873 167.585 1.00 38.21  ? 290 THR R OG1 1 
ATOM 2193 C CG2 . THR A 1 290 ? 135.818 136.304 165.787 1.00 38.21  ? 290 THR R CG2 1 
ATOM 2194 N N   . GLY A 1 291 ? 132.003 136.890 166.012 1.00 37.11  ? 291 GLY R N   1 
ATOM 2195 C CA  . GLY A 1 291 ? 130.888 136.269 165.322 1.00 37.11  ? 291 GLY R CA  1 
ATOM 2196 C C   . GLY A 1 291 ? 130.174 137.219 164.385 1.00 37.11  ? 291 GLY R C   1 
ATOM 2197 O O   . GLY A 1 291 ? 129.695 136.810 163.328 1.00 37.11  ? 291 GLY R O   1 
ATOM 2198 N N   . LEU A 1 292 ? 130.082 138.496 164.761 1.00 35.63  ? 292 LEU R N   1 
ATOM 2199 C CA  . LEU A 1 292 ? 129.547 139.497 163.842 1.00 35.63  ? 292 LEU R CA  1 
ATOM 2200 C C   . LEU A 1 292 ? 130.427 139.627 162.604 1.00 35.63  ? 292 LEU R C   1 
ATOM 2201 O O   . LEU A 1 292 ? 129.924 139.782 161.485 1.00 35.63  ? 292 LEU R O   1 
ATOM 2202 C CB  . LEU A 1 292 ? 129.410 140.847 164.546 1.00 35.63  ? 292 LEU R CB  1 
ATOM 2203 C CG  . LEU A 1 292 ? 128.278 140.976 165.565 1.00 35.63  ? 292 LEU R CG  1 
ATOM 2204 C CD1 . LEU A 1 292 ? 128.391 142.286 166.329 1.00 35.63  ? 292 LEU R CD1 1 
ATOM 2205 C CD2 . LEU A 1 292 ? 126.928 140.868 164.875 1.00 35.63  ? 292 LEU R CD2 1 
ATOM 2206 N N   . ALA A 1 293 ? 131.748 139.580 162.791 1.00 33.72  ? 293 ALA R N   1 
ATOM 2207 C CA  . ALA A 1 293 ? 132.657 139.609 161.647 1.00 33.72  ? 293 ALA R CA  1 
ATOM 2208 C C   . ALA A 1 293 ? 132.453 138.393 160.747 1.00 33.72  ? 293 ALA R C   1 
ATOM 2209 O O   . ALA A 1 293 ? 132.437 138.514 159.514 1.00 33.72  ? 293 ALA R O   1 
ATOM 2210 C CB  . ALA A 1 293 ? 134.105 139.685 162.127 1.00 33.72  ? 293 ALA R CB  1 
ATOM 2211 N N   . PHE A 1 294 ? 132.296 137.210 161.348 1.00 35.35  ? 294 PHE R N   1 
ATOM 2212 C CA  . PHE A 1 294 ? 131.988 136.013 160.566 1.00 35.35  ? 294 PHE R CA  1 
ATOM 2213 C C   . PHE A 1 294 ? 130.659 136.155 159.834 1.00 35.35  ? 294 PHE R C   1 
ATOM 2214 O O   . PHE A 1 294 ? 130.521 135.707 158.691 1.00 35.35  ? 294 PHE R O   1 
ATOM 2215 C CB  . PHE A 1 294 ? 131.967 134.773 161.462 1.00 35.35  ? 294 PHE R CB  1 
ATOM 2216 C CG  . PHE A 1 294 ? 133.330 134.265 161.842 1.00 35.35  ? 294 PHE R CG  1 
ATOM 2217 C CD1 . PHE A 1 294 ? 134.150 133.677 160.895 1.00 35.35  ? 294 PHE R CD1 1 
ATOM 2218 C CD2 . PHE A 1 294 ? 133.782 134.352 163.146 1.00 35.35  ? 294 PHE R CD2 1 
ATOM 2219 C CE1 . PHE A 1 294 ? 135.399 133.196 161.240 1.00 35.35  ? 294 PHE R CE1 1 
ATOM 2220 C CE2 . PHE A 1 294 ? 135.032 133.875 163.495 1.00 35.35  ? 294 PHE R CE2 1 
ATOM 2221 C CZ  . PHE A 1 294 ? 135.841 133.300 162.540 1.00 35.35  ? 294 PHE R CZ  1 
ATOM 2222 N N   . LEU A 1 295 ? 129.664 136.761 160.485 1.00 36.28  ? 295 LEU R N   1 
ATOM 2223 C CA  . LEU A 1 295 ? 128.375 136.982 159.841 1.00 36.28  ? 295 LEU R CA  1 
ATOM 2224 C C   . LEU A 1 295 ? 128.512 137.902 158.637 1.00 36.28  ? 295 LEU R C   1 
ATOM 2225 O O   . LEU A 1 295 ? 127.893 137.666 157.596 1.00 36.28  ? 295 LEU R O   1 
ATOM 2226 C CB  . LEU A 1 295 ? 127.379 137.563 160.844 1.00 36.28  ? 295 LEU R CB  1 
ATOM 2227 C CG  . LEU A 1 295 ? 125.909 137.575 160.418 1.00 36.28  ? 295 LEU R CG  1 
ATOM 2228 C CD1 . LEU A 1 295 ? 125.336 136.165 160.392 1.00 36.28  ? 295 LEU R CD1 1 
ATOM 2229 C CD2 . LEU A 1 295 ? 125.091 138.477 161.331 1.00 36.28  ? 295 LEU R CD2 1 
ATOM 2230 N N   . ASN A 1 296 ? 129.310 138.963 158.765 1.00 35.17  ? 296 ASN R N   1 
ATOM 2231 C CA  . ASN A 1 296 ? 129.545 139.852 157.630 1.00 35.17  ? 296 ASN R CA  1 
ATOM 2232 C C   . ASN A 1 296 ? 130.259 139.124 156.498 1.00 35.17  ? 296 ASN R C   1 
ATOM 2233 O O   . ASN A 1 296 ? 129.919 139.301 155.320 1.00 35.17  ? 296 ASN R O   1 
ATOM 2234 C CB  . ASN A 1 296 ? 130.354 141.071 158.071 1.00 35.17  ? 296 ASN R CB  1 
ATOM 2235 N N   . SER A 1 297 ? 131.259 138.306 156.836 1.00 34.61  ? 297 SER R N   1 
ATOM 2236 C CA  . SER A 1 297 ? 131.967 137.542 155.814 1.00 34.61  ? 297 SER R CA  1 
ATOM 2237 C C   . SER A 1 297 ? 131.027 136.578 155.101 1.00 34.61  ? 297 SER R C   1 
ATOM 2238 O O   . SER A 1 297 ? 131.121 136.394 153.882 1.00 34.61  ? 297 SER R O   1 
ATOM 2239 C CB  . SER A 1 297 ? 133.140 136.788 156.439 1.00 34.61  ? 297 SER R CB  1 
ATOM 2240 O OG  . SER A 1 297 ? 134.249 137.647 156.640 1.00 34.61  ? 297 SER R OG  1 
ATOM 2241 N N   . CYS A 1 298 ? 130.126 135.941 155.850 1.00 35.53  ? 298 CYS R N   1 
ATOM 2242 C CA  . CYS A 1 298 ? 129.129 135.061 155.249 1.00 35.53  ? 298 CYS R CA  1 
ATOM 2243 C C   . CYS A 1 298 ? 128.152 135.834 154.371 1.00 35.53  ? 298 CYS R C   1 
ATOM 2244 O O   . CYS A 1 298 ? 127.782 135.371 153.286 1.00 35.53  ? 298 CYS R O   1 
ATOM 2245 C CB  . CYS A 1 298 ? 128.374 134.312 156.346 1.00 35.53  ? 298 CYS R CB  1 
ATOM 2246 S SG  . CYS A 1 298 ? 127.034 133.272 155.745 1.00 35.53  ? 298 CYS R SG  1 
ATOM 2247 N N   . LEU A 1 299 ? 127.715 137.006 154.830 1.00 34.46  ? 299 LEU R N   1 
ATOM 2248 C CA  . LEU A 1 299 ? 126.677 137.766 154.148 1.00 34.46  ? 299 LEU R CA  1 
ATOM 2249 C C   . LEU A 1 299 ? 127.197 138.500 152.920 1.00 34.46  ? 299 LEU R C   1 
ATOM 2250 O O   . LEU A 1 299 ? 126.396 138.880 152.061 1.00 34.46  ? 299 LEU R O   1 
ATOM 2251 C CB  . LEU A 1 299 ? 126.037 138.746 155.140 1.00 34.46  ? 299 LEU R CB  1 
ATOM 2252 C CG  . LEU A 1 299 ? 124.797 139.583 154.806 1.00 34.46  ? 299 LEU R CG  1 
ATOM 2253 C CD1 . LEU A 1 299 ? 124.049 139.900 156.087 1.00 34.46  ? 299 LEU R CD1 1 
ATOM 2254 C CD2 . LEU A 1 299 ? 125.163 140.882 154.105 1.00 34.46  ? 299 LEU R CD2 1 
ATOM 2255 N N   . ASN A 1 300 ? 128.508 138.710 152.814 1.00 33.84  ? 300 ASN R N   1 
ATOM 2256 C CA  . ASN A 1 300 ? 129.028 139.398 151.633 1.00 33.84  ? 300 ASN R CA  1 
ATOM 2257 C C   . ASN A 1 300 ? 128.736 138.653 150.333 1.00 33.84  ? 300 ASN R C   1 
ATOM 2258 O O   . ASN A 1 300 ? 128.111 139.251 149.440 1.00 33.84  ? 300 ASN R O   1 
ATOM 2259 C CB  . ASN A 1 300 ? 130.527 139.672 151.811 1.00 33.84  ? 300 ASN R CB  1 
ATOM 2260 C CG  . ASN A 1 300 ? 130.802 140.796 152.790 1.00 33.84  ? 300 ASN R CG  1 
ATOM 2261 O OD1 . ASN A 1 300 ? 130.098 141.806 152.809 1.00 33.84  ? 300 ASN R OD1 1 
ATOM 2262 N ND2 . ASN A 1 300 ? 131.830 140.624 153.614 1.00 33.84  ? 300 ASN R ND2 1 
ATOM 2263 N N   . PRO A 1 301 ? 129.116 137.376 150.154 1.00 35.94  ? 301 PRO R N   1 
ATOM 2264 C CA  . PRO A 1 301 ? 128.876 136.740 148.843 1.00 35.94  ? 301 PRO R CA  1 
ATOM 2265 C C   . PRO A 1 301 ? 127.411 136.689 148.447 1.00 35.94  ? 301 PRO R C   1 
ATOM 2266 O O   . PRO A 1 301 ? 127.084 136.914 147.274 1.00 35.94  ? 301 PRO R O   1 
ATOM 2267 C CB  . PRO A 1 301 ? 129.456 135.327 149.009 1.00 35.94  ? 301 PRO R CB  1 
ATOM 2268 C CG  . PRO A 1 301 ? 130.243 135.333 150.246 1.00 35.94  ? 301 PRO R CG  1 
ATOM 2269 C CD  . PRO A 1 301 ? 129.827 136.483 151.087 1.00 35.94  ? 301 PRO R CD  1 
ATOM 2270 N N   . ILE A 1 302 ? 126.513 136.406 149.394 1.00 37.90  ? 302 ILE R N   1 
ATOM 2271 C CA  . ILE A 1 302 ? 125.093 136.353 149.065 1.00 37.90  ? 302 ILE R CA  1 
ATOM 2272 C C   . ILE A 1 302 ? 124.579 137.738 148.689 1.00 37.90  ? 302 ILE R C   1 
ATOM 2273 O O   . ILE A 1 302 ? 123.658 137.866 147.872 1.00 37.90  ? 302 ILE R O   1 
ATOM 2274 C CB  . ILE A 1 302 ? 124.294 135.732 150.231 1.00 37.90  ? 302 ILE R CB  1 
ATOM 2275 C CG1 . ILE A 1 302 ? 122.818 135.579 149.863 1.00 37.90  ? 302 ILE R CG1 1 
ATOM 2276 C CG2 . ILE A 1 302 ? 124.433 136.556 151.495 1.00 37.90  ? 302 ILE R CG2 1 
ATOM 2277 C CD1 . ILE A 1 302 ? 122.039 134.701 150.819 1.00 37.90  ? 302 ILE R CD1 1 
ATOM 2278 N N   . LEU A 1 303 ? 125.166 138.791 149.259 1.00 33.48  ? 303 LEU R N   1 
ATOM 2279 C CA  . LEU A 1 303 ? 124.739 140.151 148.956 1.00 33.48  ? 303 LEU R CA  1 
ATOM 2280 C C   . LEU A 1 303 ? 125.380 140.701 147.685 1.00 33.48  ? 303 LEU R C   1 
ATOM 2281 O O   . LEU A 1 303 ? 124.888 141.695 147.140 1.00 33.48  ? 303 LEU R O   1 
ATOM 2282 C CB  . LEU A 1 303 ? 125.041 141.055 150.158 1.00 33.48  ? 303 LEU R CB  1 
ATOM 2283 C CG  . LEU A 1 303 ? 125.004 142.579 150.049 1.00 33.48  ? 303 LEU R CG  1 
ATOM 2284 C CD1 . LEU A 1 303 ? 123.574 143.068 149.899 1.00 33.48  ? 303 LEU R CD1 1 
ATOM 2285 C CD2 . LEU A 1 303 ? 125.653 143.199 151.272 1.00 33.48  ? 303 LEU R CD2 1 
ATOM 2286 N N   . TYR A 1 304 ? 126.448 140.077 147.188 1.00 33.34  ? 304 TYR R N   1 
ATOM 2287 C CA  . TYR A 1 304 ? 127.029 140.530 145.926 1.00 33.34  ? 304 TYR R CA  1 
ATOM 2288 C C   . TYR A 1 304 ? 126.575 139.708 144.721 1.00 33.34  ? 304 TYR R C   1 
ATOM 2289 O O   . TYR A 1 304 ? 126.121 140.276 143.723 1.00 33.34  ? 304 TYR R O   1 
ATOM 2290 C CB  . TYR A 1 304 ? 128.563 140.526 145.987 1.00 33.34  ? 304 TYR R CB  1 
ATOM 2291 C CG  . TYR A 1 304 ? 129.190 141.576 146.880 1.00 33.34  ? 304 TYR R CG  1 
ATOM 2292 C CD1 . TYR A 1 304 ? 129.325 142.889 146.447 1.00 33.34  ? 304 TYR R CD1 1 
ATOM 2293 C CD2 . TYR A 1 304 ? 129.701 141.248 148.126 1.00 33.34  ? 304 TYR R CD2 1 
ATOM 2294 C CE1 . TYR A 1 304 ? 129.912 143.850 147.248 1.00 33.34  ? 304 TYR R CE1 1 
ATOM 2295 C CE2 . TYR A 1 304 ? 130.286 142.200 148.935 1.00 33.34  ? 304 TYR R CE2 1 
ATOM 2296 C CZ  . TYR A 1 304 ? 130.393 143.498 148.490 1.00 33.34  ? 304 TYR R CZ  1 
ATOM 2297 O OH  . TYR A 1 304 ? 130.982 144.448 149.292 1.00 33.34  ? 304 TYR R OH  1 
ATOM 2298 N N   . VAL A 1 305 ? 126.688 138.381 144.786 1.00 39.52  ? 305 VAL R N   1 
ATOM 2299 C CA  . VAL A 1 305 ? 126.700 137.583 143.562 1.00 39.52  ? 305 VAL R CA  1 
ATOM 2300 C C   . VAL A 1 305 ? 125.314 137.088 143.153 1.00 39.52  ? 305 VAL R C   1 
ATOM 2301 O O   . VAL A 1 305 ? 125.024 136.976 141.957 1.00 39.52  ? 305 VAL R O   1 
ATOM 2302 C CB  . VAL A 1 305 ? 127.689 136.404 143.689 1.00 39.52  ? 305 VAL R CB  1 
ATOM 2303 C CG1 . VAL A 1 305 ? 127.126 135.287 144.559 1.00 39.52  ? 305 VAL R CG1 1 
ATOM 2304 C CG2 . VAL A 1 305 ? 128.062 135.874 142.311 1.00 39.52  ? 305 VAL R CG2 1 
ATOM 2305 N N   . LEU A 1 306 ? 124.446 136.787 144.119 1.00 41.56  ? 306 LEU R N   1 
ATOM 2306 C CA  . LEU A 1 306 ? 123.192 136.108 143.811 1.00 41.56  ? 306 LEU R CA  1 
ATOM 2307 C C   . LEU A 1 306 ? 121.958 136.980 144.021 1.00 41.56  ? 306 LEU R C   1 
ATOM 2308 O O   . LEU A 1 306 ? 120.836 136.469 143.947 1.00 41.56  ? 306 LEU R O   1 
ATOM 2309 C CB  . LEU A 1 306 ? 123.078 134.817 144.629 1.00 41.56  ? 306 LEU R CB  1 
ATOM 2310 C CG  . LEU A 1 306 ? 122.988 134.885 146.155 1.00 41.56  ? 306 LEU R CG  1 
ATOM 2311 C CD1 . LEU A 1 306 ? 121.537 134.880 146.620 1.00 41.56  ? 306 LEU R CD1 1 
ATOM 2312 C CD2 . LEU A 1 306 ? 123.758 133.733 146.780 1.00 41.56  ? 306 LEU R CD2 1 
ATOM 2313 N N   . ILE A 1 307 ? 122.128 138.278 144.266 1.00 43.35  ? 307 ILE R N   1 
ATOM 2314 C CA  . ILE A 1 307 ? 120.994 139.169 144.491 1.00 43.35  ? 307 ILE R CA  1 
ATOM 2315 C C   . ILE A 1 307 ? 120.849 140.225 143.403 1.00 43.35  ? 307 ILE R C   1 
ATOM 2316 O O   . ILE A 1 307 ? 119.754 140.793 143.256 1.00 43.35  ? 307 ILE R O   1 
ATOM 2317 C CB  . ILE A 1 307 ? 121.076 139.844 145.878 1.00 43.35  ? 307 ILE R CB  1 
ATOM 2318 C CG1 . ILE A 1 307 ? 119.724 140.437 146.282 1.00 43.35  ? 307 ILE R CG1 1 
ATOM 2319 C CG2 . ILE A 1 307 ? 122.132 140.928 145.877 1.00 43.35  ? 307 ILE R CG2 1 
ATOM 2320 C CD1 . ILE A 1 307 ? 118.645 139.401 146.507 1.00 43.35  ? 307 ILE R CD1 1 
ATOM 2321 N N   . SER A 1 308 ? 121.894 140.488 142.624 1.00 48.72  ? 308 SER R N   1 
ATOM 2322 C CA  . SER A 1 308 ? 121.841 141.536 141.618 1.00 48.72  ? 308 SER R CA  1 
ATOM 2323 C C   . SER A 1 308 ? 120.947 141.126 140.450 1.00 48.72  ? 308 SER R C   1 
ATOM 2324 O O   . SER A 1 308 ? 120.645 139.948 140.242 1.00 48.72  ? 308 SER R O   1 
ATOM 2325 C CB  . SER A 1 308 ? 123.244 141.868 141.111 1.00 48.72  ? 308 SER R CB  1 
ATOM 2326 O OG  . SER A 1 308 ? 123.804 140.773 140.413 1.00 48.72  ? 308 SER R OG  1 
ATOM 2327 N N   . LYS A 1 309 ? 120.524 142.131 139.679 1.00 51.36  ? 309 LYS R N   1 
ATOM 2328 C CA  . LYS A 1 309 ? 119.626 141.890 138.556 1.00 51.36  ? 309 LYS R CA  1 
ATOM 2329 C C   . LYS A 1 309 ? 120.330 141.241 137.371 1.00 51.36  ? 309 LYS R C   1 
ATOM 2330 O O   . LYS A 1 309 ? 119.661 140.621 136.537 1.00 51.36  ? 309 LYS R O   1 
ATOM 2331 C CB  . LYS A 1 309 ? 118.971 143.201 138.116 1.00 51.36  ? 309 LYS R CB  1 
ATOM 2332 C CG  . LYS A 1 309 ? 118.392 144.023 139.258 1.00 51.36  ? 309 LYS R CG  1 
ATOM 2333 C CD  . LYS A 1 309 ? 117.404 143.210 140.081 1.00 51.36  ? 309 LYS R CD  1 
ATOM 2334 C CE  . LYS A 1 309 ? 117.501 143.554 141.559 1.00 51.36  ? 309 LYS R CE  1 
ATOM 2335 N NZ  . LYS A 1 309 ? 116.363 142.991 142.337 1.00 51.36  ? 309 LYS R NZ  1 
ATOM 2336 N N   . LYS A 1 310 ? 121.655 141.375 137.271 1.00 51.68  ? 310 LYS R N   1 
ATOM 2337 C CA  . LYS A 1 310 ? 122.379 140.745 136.171 1.00 51.68  ? 310 LYS R CA  1 
ATOM 2338 C C   . LYS A 1 310 ? 122.254 139.228 136.228 1.00 51.68  ? 310 LYS R C   1 
ATOM 2339 O O   . LYS A 1 310 ? 122.035 138.575 135.201 1.00 51.68  ? 310 LYS R O   1 
ATOM 2340 C CB  . LYS A 1 310 ? 123.848 141.166 136.198 1.00 51.68  ? 310 LYS R CB  1 
ATOM 2341 C CG  . LYS A 1 310 ? 124.147 142.454 135.442 1.00 51.68  ? 310 LYS R CG  1 
ATOM 2342 C CD  . LYS A 1 310 ? 123.359 142.540 134.143 1.00 51.68  ? 310 LYS R CD  1 
ATOM 2343 C CE  . LYS A 1 310 ? 124.016 141.724 133.041 1.00 51.68  ? 310 LYS R CE  1 
ATOM 2344 N NZ  . LYS A 1 310 ? 123.424 142.016 131.706 1.00 51.68  ? 310 LYS R NZ  1 
ATOM 2345 N N   . PHE A 1 311 ? 122.388 138.652 137.418 1.00 52.45  ? 311 PHE R N   1 
ATOM 2346 C CA  . PHE A 1 311 ? 122.176 137.228 137.622 1.00 52.45  ? 311 PHE R CA  1 
ATOM 2347 C C   . PHE A 1 311 ? 120.704 136.980 137.951 1.00 52.45  ? 311 PHE R C   1 
ATOM 2348 O O   . PHE A 1 311 ? 119.848 137.845 137.749 1.00 52.45  ? 311 PHE R O   1 
ATOM 2349 C CB  . PHE A 1 311 ? 123.115 136.696 138.704 1.00 52.45  ? 311 PHE R CB  1 
ATOM 2350 C CG  . PHE A 1 311 ? 124.542 137.145 138.547 1.00 52.45  ? 311 PHE R CG  1 
ATOM 2351 C CD1 . PHE A 1 311 ? 125.436 136.399 137.797 1.00 52.45  ? 311 PHE R CD1 1 
ATOM 2352 C CD2 . PHE A 1 311 ? 124.993 138.304 139.154 1.00 52.45  ? 311 PHE R CD2 1 
ATOM 2353 C CE1 . PHE A 1 311 ? 126.749 136.804 137.650 1.00 52.45  ? 311 PHE R CE1 1 
ATOM 2354 C CE2 . PHE A 1 311 ? 126.305 138.714 139.011 1.00 52.45  ? 311 PHE R CE2 1 
ATOM 2355 C CZ  . PHE A 1 311 ? 127.184 137.963 138.259 1.00 52.45  ? 311 PHE R CZ  1 
ATOM 2356 N N   . GLN A 1 312 ? 120.398 135.776 138.437 1.00 56.74  ? 312 GLN R N   1 
ATOM 2357 C CA  . GLN A 1 312 ? 119.062 135.281 138.763 1.00 56.74  ? 312 GLN R CA  1 
ATOM 2358 C C   . GLN A 1 312 ? 118.212 135.027 137.525 1.00 56.74  ? 312 GLN R C   1 
ATOM 2359 O O   . GLN A 1 312 ? 117.036 134.668 137.663 1.00 56.74  ? 312 GLN R O   1 
ATOM 2360 C CB  . GLN A 1 312 ? 118.292 136.215 139.710 1.00 56.74  ? 312 GLN R CB  1 
ATOM 2361 C CG  . GLN A 1 312 ? 118.935 136.395 141.074 1.00 56.74  ? 312 GLN R CG  1 
ATOM 2362 C CD  . GLN A 1 312 ? 118.165 137.358 141.955 1.00 56.74  ? 312 GLN R CD  1 
ATOM 2363 O OE1 . GLN A 1 312 ? 117.341 138.135 141.474 1.00 56.74  ? 312 GLN R OE1 1 
ATOM 2364 N NE2 . GLN A 1 312 ? 118.429 137.310 143.256 1.00 56.74  ? 312 GLN R NE2 1 
ATOM 2365 N N   . ALA A 1 313 ? 118.759 135.199 136.322 1.00 67.37  ? 313 ALA R N   1 
ATOM 2366 C CA  . ALA A 1 313 ? 118.035 134.901 135.095 1.00 67.37  ? 313 ALA R CA  1 
ATOM 2367 C C   . ALA A 1 313 ? 118.392 133.546 134.502 1.00 67.37  ? 313 ALA R C   1 
ATOM 2368 O O   . ALA A 1 313 ? 117.592 132.991 133.742 1.00 67.37  ? 313 ALA R O   1 
ATOM 2369 C CB  . ALA A 1 313 ? 118.291 135.991 134.047 1.00 67.37  ? 313 ALA R CB  1 
ATOM 2370 N N   . ARG A 1 314 ? 119.564 133.007 134.829 1.00 63.85  ? 314 ARG R N   1 
ATOM 2371 C CA  . ARG A 1 314 ? 119.998 131.712 134.323 1.00 63.85  ? 314 ARG R CA  1 
ATOM 2372 C C   . ARG A 1 314 ? 119.524 130.548 135.184 1.00 63.85  ? 314 ARG R C   1 
ATOM 2373 O O   . ARG A 1 314 ? 119.751 129.392 134.813 1.00 63.85  ? 314 ARG R O   1 
ATOM 2374 C CB  . ARG A 1 314 ? 121.525 131.678 134.207 1.00 63.85  ? 314 ARG R CB  1 
ATOM 2375 C CG  . ARG A 1 314 ? 122.104 132.781 133.336 1.00 63.85  ? 314 ARG R CG  1 
ATOM 2376 C CD  . ARG A 1 314 ? 123.620 132.842 133.454 1.00 63.85  ? 314 ARG R CD  1 
ATOM 2377 N NE  . ARG A 1 314 ? 124.139 134.192 133.262 1.00 63.85  ? 314 ARG R NE  1 
ATOM 2378 C CZ  . ARG A 1 314 ? 124.000 135.184 134.132 1.00 63.85  ? 314 ARG R CZ  1 
ATOM 2379 N NH1 . ARG A 1 314 ? 123.375 135.012 135.285 1.00 63.85  ? 314 ARG R NH1 1 
ATOM 2380 N NH2 . ARG A 1 314 ? 124.507 136.379 133.840 1.00 63.85  ? 314 ARG R NH2 1 
ATOM 2381 N N   . PHE A 1 315 ? 118.879 130.819 136.314 1.00 65.47  ? 315 PHE R N   1 
ATOM 2382 C CA  . PHE A 1 315 ? 118.371 129.758 137.175 1.00 65.47  ? 315 PHE R CA  1 
ATOM 2383 C C   . PHE A 1 315 ? 117.062 130.176 137.837 1.00 65.47  ? 315 PHE R C   1 
ATOM 2384 O O   . PHE A 1 315 ? 116.436 131.156 137.433 1.00 65.47  ? 315 PHE R O   1 
ATOM 2385 C CB  . PHE A 1 315 ? 119.407 129.381 138.239 1.00 65.47  ? 315 PHE R CB  1 
ATOM 2386 C CG  . PHE A 1 315 ? 119.694 130.476 139.231 1.00 65.47  ? 315 PHE R CG  1 
ATOM 2387 C CD1 . PHE A 1 315 ? 120.615 131.470 138.943 1.00 65.47  ? 315 PHE R CD1 1 
ATOM 2388 C CD2 . PHE A 1 315 ? 119.055 130.500 140.461 1.00 65.47  ? 315 PHE R CD2 1 
ATOM 2389 C CE1 . PHE A 1 315 ? 120.885 132.471 139.856 1.00 65.47  ? 315 PHE R CE1 1 
ATOM 2390 C CE2 . PHE A 1 315 ? 119.320 131.500 141.377 1.00 65.47  ? 315 PHE R CE2 1 
ATOM 2391 C CZ  . PHE A 1 315 ? 120.236 132.487 141.074 1.00 65.47  ? 315 PHE R CZ  1 
ATOM 2392 N N   . THR B 2 3   ? 164.401 130.734 204.743 1.00 92.09  ? 23  THR L N   1 
ATOM 2393 C CA  . THR B 2 3   ? 163.616 131.479 205.719 1.00 92.09  ? 23  THR L CA  1 
ATOM 2394 C C   . THR B 2 3   ? 162.248 130.838 205.926 1.00 92.09  ? 23  THR L C   1 
ATOM 2395 O O   . THR B 2 3   ? 161.935 129.812 205.321 1.00 92.09  ? 23  THR L O   1 
ATOM 2396 C CB  . THR B 2 3   ? 163.425 132.946 205.290 1.00 92.09  ? 23  THR L CB  1 
ATOM 2397 O OG1 . THR B 2 3   ? 162.640 133.635 206.271 1.00 92.09  ? 23  THR L OG1 1 
ATOM 2398 C CG2 . THR B 2 3   ? 162.725 133.020 203.942 1.00 92.09  ? 23  THR L CG2 1 
ATOM 2399 N N   . GLU B 2 4   ? 161.437 131.450 206.793 1.00 91.57  ? 24  GLU L N   1 
ATOM 2400 C CA  . GLU B 2 4   ? 160.092 130.937 207.037 1.00 91.57  ? 24  GLU L CA  1 
ATOM 2401 C C   . GLU B 2 4   ? 159.228 131.038 205.786 1.00 91.57  ? 24  GLU L C   1 
ATOM 2402 O O   . GLU B 2 4   ? 158.433 130.136 205.496 1.00 91.57  ? 24  GLU L O   1 
ATOM 2403 C CB  . GLU B 2 4   ? 159.446 131.691 208.199 1.00 91.57  ? 24  GLU L CB  1 
ATOM 2404 N N   . ALA B 2 5   ? 159.366 132.134 205.036 1.00 90.16  ? 25  ALA L N   1 
ATOM 2405 C CA  . ALA B 2 5   ? 158.598 132.291 203.805 1.00 90.16  ? 25  ALA L CA  1 
ATOM 2406 C C   . ALA B 2 5   ? 158.964 131.219 202.786 1.00 90.16  ? 25  ALA L C   1 
ATOM 2407 O O   . ALA B 2 5   ? 158.086 130.669 202.112 1.00 90.16  ? 25  ALA L O   1 
ATOM 2408 C CB  . ALA B 2 5   ? 158.819 133.686 203.222 1.00 90.16  ? 25  ALA L CB  1 
ATOM 2409 N N   . GLN B 2 6   ? 160.256 130.909 202.658 1.00 91.51  ? 26  GLN L N   1 
ATOM 2410 C CA  . GLN B 2 6   ? 160.679 129.860 201.735 1.00 91.51  ? 26  GLN L CA  1 
ATOM 2411 C C   . GLN B 2 6   ? 160.143 128.499 202.161 1.00 91.51  ? 26  GLN L C   1 
ATOM 2412 O O   . GLN B 2 6   ? 159.727 127.694 201.318 1.00 91.51  ? 26  GLN L O   1 
ATOM 2413 C CB  . GLN B 2 6   ? 162.204 129.831 201.637 1.00 91.51  ? 26  GLN L CB  1 
ATOM 2414 N N   . ARG B 2 7   ? 160.157 128.219 203.467 1.00 93.16  ? 27  ARG L N   1 
ATOM 2415 C CA  . ARG B 2 7   ? 159.609 126.958 203.959 1.00 93.16  ? 27  ARG L CA  1 
ATOM 2416 C C   . ARG B 2 7   ? 158.117 126.858 203.673 1.00 93.16  ? 27  ARG L C   1 
ATOM 2417 O O   . ARG B 2 7   ? 157.628 125.808 203.238 1.00 93.16  ? 27  ARG L O   1 
ATOM 2418 C CB  . ARG B 2 7   ? 159.881 126.816 205.457 1.00 93.16  ? 27  ARG L CB  1 
ATOM 2419 N N   . ARG B 2 8   ? 157.377 127.946 203.900 1.00 93.64  ? 28  ARG L N   1 
ATOM 2420 C CA  . ARG B 2 8   ? 155.951 127.947 203.592 1.00 93.64  ? 28  ARG L CA  1 
ATOM 2421 C C   . ARG B 2 8   ? 155.713 127.751 202.100 1.00 93.64  ? 28  ARG L C   1 
ATOM 2422 O O   . ARG B 2 8   ? 154.796 127.025 201.700 1.00 93.64  ? 28  ARG L O   1 
ATOM 2423 C CB  . ARG B 2 8   ? 155.310 129.248 204.075 1.00 93.64  ? 28  ARG L CB  1 
ATOM 2424 N N   . GLY B 2 9   ? 156.532 128.390 201.263 1.00 89.69  ? 29  GLY L N   1 
ATOM 2425 C CA  . GLY B 2 9   ? 156.374 128.235 199.827 1.00 89.69  ? 29  GLY L CA  1 
ATOM 2426 C C   . GLY B 2 9   ? 156.632 126.818 199.354 1.00 89.69  ? 29  GLY L C   1 
ATOM 2427 O O   . GLY B 2 9   ? 155.884 126.281 198.533 1.00 89.69  ? 29  GLY L O   1 
ATOM 2428 N N   . LEU B 2 10  ? 157.697 126.191 199.862 1.00 91.38  ? 30  LEU L N   1 
ATOM 2429 C CA  . LEU B 2 10  ? 157.967 124.809 199.479 1.00 91.38  ? 30  LEU L CA  1 
ATOM 2430 C C   . LEU B 2 10  ? 156.898 123.865 200.016 1.00 91.38  ? 30  LEU L C   1 
ATOM 2431 O O   . LEU B 2 10  ? 156.545 122.889 199.344 1.00 91.38  ? 30  LEU L O   1 
ATOM 2432 C CB  . LEU B 2 10  ? 159.367 124.387 199.939 1.00 91.38  ? 30  LEU L CB  1 
ATOM 2433 C CG  . LEU B 2 10  ? 159.779 124.363 201.415 1.00 91.38  ? 30  LEU L CG  1 
ATOM 2434 C CD1 . LEU B 2 10  ? 159.352 123.078 202.118 1.00 91.38  ? 30  LEU L CD1 1 
ATOM 2435 C CD2 . LEU B 2 10  ? 161.282 124.573 201.548 1.00 91.38  ? 30  LEU L CD2 1 
ATOM 2436 N N   . GLN B 2 11  ? 156.359 124.144 201.207 1.00 91.98  ? 31  GLN L N   1 
ATOM 2437 C CA  . GLN B 2 11  ? 155.253 123.340 201.720 1.00 91.98  ? 31  GLN L CA  1 
ATOM 2438 C C   . GLN B 2 11  ? 154.022 123.464 200.830 1.00 91.98  ? 31  GLN L C   1 
ATOM 2439 O O   . GLN B 2 11  ? 153.345 122.468 200.552 1.00 91.98  ? 31  GLN L O   1 
ATOM 2440 C CB  . GLN B 2 11  ? 154.925 123.754 203.154 1.00 91.98  ? 31  GLN L CB  1 
ATOM 2441 N N   . VAL B 2 12  ? 153.717 124.682 200.374 1.00 91.56  ? 32  VAL L N   1 
ATOM 2442 C CA  . VAL B 2 12  ? 152.578 124.882 199.481 1.00 91.56  ? 32  VAL L CA  1 
ATOM 2443 C C   . VAL B 2 12  ? 152.805 124.166 198.154 1.00 91.56  ? 32  VAL L C   1 
ATOM 2444 O O   . VAL B 2 12  ? 151.885 123.551 197.600 1.00 91.56  ? 32  VAL L O   1 
ATOM 2445 C CB  . VAL B 2 12  ? 152.315 126.386 199.282 1.00 91.56  ? 32  VAL L CB  1 
ATOM 2446 C CG1 . VAL B 2 12  ? 151.320 126.612 198.153 1.00 91.56  ? 32  VAL L CG1 1 
ATOM 2447 C CG2 . VAL B 2 12  ? 151.801 127.007 200.571 1.00 91.56  ? 32  VAL L CG2 1 
ATOM 2448 N N   . ALA B 2 13  ? 154.027 124.237 197.621 1.00 89.64  ? 33  ALA L N   1 
ATOM 2449 C CA  . ALA B 2 13  ? 154.331 123.543 196.373 1.00 89.64  ? 33  ALA L CA  1 
ATOM 2450 C C   . ALA B 2 13  ? 154.185 122.033 196.528 1.00 89.64  ? 33  ALA L C   1 
ATOM 2451 O O   . ALA B 2 13  ? 153.644 121.358 195.643 1.00 89.64  ? 33  ALA L O   1 
ATOM 2452 C CB  . ALA B 2 13  ? 155.741 123.902 195.903 1.00 89.64  ? 33  ALA L CB  1 
ATOM 2453 N N   . LEU B 2 14  ? 154.660 121.484 197.648 1.00 93.74  ? 34  LEU L N   1 
ATOM 2454 C CA  . LEU B 2 14  ? 154.517 120.052 197.886 1.00 93.74  ? 34  LEU L CA  1 
ATOM 2455 C C   . LEU B 2 14  ? 153.057 119.655 198.072 1.00 93.74  ? 34  LEU L C   1 
ATOM 2456 O O   . LEU B 2 14  ? 152.647 118.580 197.622 1.00 93.74  ? 34  LEU L O   1 
ATOM 2457 C CB  . LEU B 2 14  ? 155.347 119.639 199.100 1.00 93.74  ? 34  LEU L CB  1 
ATOM 2458 C CG  . LEU B 2 14  ? 155.329 118.155 199.458 1.00 93.74  ? 34  LEU L CG  1 
ATOM 2459 C CD1 . LEU B 2 14  ? 156.335 117.398 198.610 1.00 93.74  ? 34  LEU L CD1 1 
ATOM 2460 C CD2 . LEU B 2 14  ? 155.626 117.969 200.932 1.00 93.74  ? 34  LEU L CD2 1 
ATOM 2461 N N   . GLU B 2 15  ? 152.262 120.501 198.731 1.00 95.75  ? 35  GLU L N   1 
ATOM 2462 C CA  . GLU B 2 15  ? 150.832 120.232 198.849 1.00 95.75  ? 35  GLU L CA  1 
ATOM 2463 C C   . GLU B 2 15  ? 150.158 120.241 197.483 1.00 95.75  ? 35  GLU L C   1 
ATOM 2464 O O   . GLU B 2 15  ? 149.279 119.414 197.209 1.00 95.75  ? 35  GLU L O   1 
ATOM 2465 C CB  . GLU B 2 15  ? 150.180 121.256 199.778 1.00 95.75  ? 35  GLU L CB  1 
ATOM 2466 N N   . GLU B 2 16  ? 150.550 121.177 196.615 1.00 92.85  ? 36  GLU L N   1 
ATOM 2467 C CA  . GLU B 2 16  ? 150.017 121.201 195.256 1.00 92.85  ? 36  GLU L CA  1 
ATOM 2468 C C   . GLU B 2 16  ? 150.409 119.942 194.492 1.00 92.85  ? 36  GLU L C   1 
ATOM 2469 O O   . GLU B 2 16  ? 149.610 119.400 193.719 1.00 92.85  ? 36  GLU L O   1 
ATOM 2470 C CB  . GLU B 2 16  ? 150.505 122.450 194.523 1.00 92.85  ? 36  GLU L CB  1 
ATOM 2471 N N   . PHE B 2 17  ? 151.642 119.470 194.688 1.00 95.49  ? 37  PHE L N   1 
ATOM 2472 C CA  . PHE B 2 17  ? 152.059 118.202 194.095 1.00 95.49  ? 37  PHE L CA  1 
ATOM 2473 C C   . PHE B 2 17  ? 151.188 117.054 194.591 1.00 95.49  ? 37  PHE L C   1 
ATOM 2474 O O   . PHE B 2 17  ? 150.740 116.211 193.805 1.00 95.49  ? 37  PHE L O   1 
ATOM 2475 C CB  . PHE B 2 17  ? 153.530 117.931 194.417 1.00 95.49  ? 37  PHE L CB  1 
ATOM 2476 C CG  . PHE B 2 17  ? 154.202 116.984 193.459 1.00 95.49  ? 37  PHE L CG  1 
ATOM 2477 C CD1 . PHE B 2 17  ? 153.861 115.641 193.437 1.00 95.49  ? 37  PHE L CD1 1 
ATOM 2478 C CD2 . PHE B 2 17  ? 155.186 117.431 192.595 1.00 95.49  ? 37  PHE L CD2 1 
ATOM 2479 C CE1 . PHE B 2 17  ? 154.476 114.766 192.564 1.00 95.49  ? 37  PHE L CE1 1 
ATOM 2480 C CE2 . PHE B 2 17  ? 155.807 116.558 191.720 1.00 95.49  ? 37  PHE L CE2 1 
ATOM 2481 C CZ  . PHE B 2 17  ? 155.450 115.226 191.704 1.00 95.49  ? 37  PHE L CZ  1 
ATOM 2482 N N   . HIS B 2 18  ? 150.937 117.007 195.900 1.00 98.78  ? 38  HIS L N   1 
ATOM 2483 C CA  . HIS B 2 18  ? 150.161 115.917 196.479 1.00 98.78  ? 38  HIS L CA  1 
ATOM 2484 C C   . HIS B 2 18  ? 148.688 115.984 196.100 1.00 98.78  ? 38  HIS L C   1 
ATOM 2485 O O   . HIS B 2 18  ? 148.005 114.954 196.141 1.00 98.78  ? 38  HIS L O   1 
ATOM 2486 C CB  . HIS B 2 18  ? 150.306 115.920 198.002 1.00 98.78  ? 38  HIS L CB  1 
ATOM 2487 N N   . LYS B 2 19  ? 148.182 117.167 195.744 1.00 99.94  ? 39  LYS L N   1 
ATOM 2488 C CA  . LYS B 2 19  ? 146.774 117.290 195.376 1.00 99.94  ? 39  LYS L CA  1 
ATOM 2489 C C   . LYS B 2 19  ? 146.455 116.484 194.123 1.00 99.94  ? 39  LYS L C   1 
ATOM 2490 O O   . LYS B 2 19  ? 145.431 115.794 194.064 1.00 99.94  ? 39  LYS L O   1 
ATOM 2491 C CB  . LYS B 2 19  ? 146.412 118.761 195.176 1.00 99.94  ? 39  LYS L CB  1 
ATOM 2492 N N   . HIS B 2 20  ? 147.322 116.556 193.109 1.00 97.67  ? 40  HIS L N   1 
ATOM 2493 C CA  . HIS B 2 20  ? 147.109 115.822 191.870 1.00 97.67  ? 40  HIS L CA  1 
ATOM 2494 C C   . HIS B 2 20  ? 148.443 115.650 191.168 1.00 97.67  ? 40  HIS L C   1 
ATOM 2495 O O   . HIS B 2 20  ? 149.274 116.567 191.220 1.00 97.67  ? 40  HIS L O   1 
ATOM 2496 C CB  . HIS B 2 20  ? 146.117 116.547 190.953 1.00 97.67  ? 40  HIS L CB  1 
ATOM 2497 C CG  . HIS B 2 20  ? 146.561 117.917 190.545 1.00 97.67  ? 40  HIS L CG  1 
ATOM 2498 N ND1 . HIS B 2 20  ? 146.513 119.000 191.397 1.00 97.67  ? 40  HIS L ND1 1 
ATOM 2499 C CD2 . HIS B 2 20  ? 147.061 118.381 189.375 1.00 97.67  ? 40  HIS L CD2 1 
ATOM 2500 C CE1 . HIS B 2 20  ? 146.964 120.071 190.770 1.00 97.67  ? 40  HIS L CE1 1 
ATOM 2501 N NE2 . HIS B 2 20  ? 147.303 119.723 189.542 1.00 97.67  ? 40  HIS L NE2 1 
ATOM 2502 N N   . PRO B 2 21  ? 148.689 114.508 190.509 1.00 103.97 ? 41  PRO L N   1 
ATOM 2503 C CA  . PRO B 2 21  ? 149.947 114.275 189.794 1.00 103.97 ? 41  PRO L CA  1 
ATOM 2504 C C   . PRO B 2 21  ? 149.960 114.915 188.409 1.00 103.97 ? 41  PRO L C   1 
ATOM 2505 O O   . PRO B 2 21  ? 150.946 115.565 188.061 1.00 103.97 ? 41  PRO L O   1 
ATOM 2506 C CB  . PRO B 2 21  ? 150.010 112.752 189.690 1.00 103.97 ? 41  PRO L CB  1 
ATOM 2507 C CG  . PRO B 2 21  ? 148.582 112.321 189.668 1.00 103.97 ? 41  PRO L CG  1 
ATOM 2508 C CD  . PRO B 2 21  ? 147.779 113.352 190.423 1.00 103.97 ? 41  PRO L CD  1 
ATOM 2509 N N   . TRP B 2 25  ? 153.009 107.700 197.282 1.00 99.60  ? 45  TRP L N   1 
ATOM 2510 C CA  . TRP B 2 25  ? 153.260 108.460 196.063 1.00 99.60  ? 45  TRP L CA  1 
ATOM 2511 C C   . TRP B 2 25  ? 153.958 109.780 196.375 1.00 99.60  ? 45  TRP L C   1 
ATOM 2512 O O   . TRP B 2 25  ? 154.649 110.343 195.525 1.00 99.60  ? 45  TRP L O   1 
ATOM 2513 C CB  . TRP B 2 25  ? 151.952 108.720 195.313 1.00 99.60  ? 45  TRP L CB  1 
ATOM 2514 N N   . ALA B 2 26  ? 153.769 110.270 197.597 1.00 98.58  ? 46  ALA L N   1 
ATOM 2515 C CA  . ALA B 2 26  ? 154.393 111.519 198.009 1.00 98.58  ? 46  ALA L CA  1 
ATOM 2516 C C   . ALA B 2 26  ? 155.903 111.352 198.120 1.00 98.58  ? 46  ALA L C   1 
ATOM 2517 O O   . ALA B 2 26  ? 156.399 110.324 198.588 1.00 98.58  ? 46  ALA L O   1 
ATOM 2518 C CB  . ALA B 2 26  ? 153.815 111.988 199.343 1.00 98.58  ? 46  ALA L CB  1 
ATOM 2519 N N   . PHE B 2 27  ? 156.635 112.375 197.686 1.00 94.76  ? 47  PHE L N   1 
ATOM 2520 C CA  . PHE B 2 27  ? 158.090 112.365 197.710 1.00 94.76  ? 47  PHE L CA  1 
ATOM 2521 C C   . PHE B 2 27  ? 158.595 113.619 198.406 1.00 94.76  ? 47  PHE L C   1 
ATOM 2522 O O   . PHE B 2 27  ? 158.075 114.715 198.183 1.00 94.76  ? 47  PHE L O   1 
ATOM 2523 C CB  . PHE B 2 27  ? 158.670 112.281 196.293 1.00 94.76  ? 47  PHE L CB  1 
ATOM 2524 N N   . GLN B 2 28  ? 159.608 113.451 199.249 1.00 95.73  ? 48  GLN L N   1 
ATOM 2525 C CA  . GLN B 2 28  ? 160.216 114.556 199.974 1.00 95.73  ? 48  GLN L CA  1 
ATOM 2526 C C   . GLN B 2 28  ? 161.461 115.048 199.245 1.00 95.73  ? 48  GLN L C   1 
ATOM 2527 O O   . GLN B 2 28  ? 161.892 114.484 198.238 1.00 95.73  ? 48  GLN L O   1 
ATOM 2528 C CB  . GLN B 2 28  ? 160.567 114.135 201.404 1.00 95.73  ? 48  GLN L CB  1 
ATOM 2529 C CG  . GLN B 2 28  ? 161.759 113.197 201.500 1.00 95.73  ? 48  GLN L CG  1 
ATOM 2530 C CD  . GLN B 2 28  ? 162.149 112.895 202.933 1.00 95.73  ? 48  GLN L CD  1 
ATOM 2531 O OE1 . GLN B 2 28  ? 161.547 113.412 203.874 1.00 95.73  ? 48  GLN L OE1 1 
ATOM 2532 N NE2 . GLN B 2 28  ? 163.163 112.055 203.106 1.00 95.73  ? 48  GLN L NE2 1 
ATOM 2533 N N   . GLU B 2 29  ? 162.037 116.127 199.771 1.00 94.92  ? 49  GLU L N   1 
ATOM 2534 C CA  . GLU B 2 29  ? 163.265 116.665 199.203 1.00 94.92  ? 49  GLU L CA  1 
ATOM 2535 C C   . GLU B 2 29  ? 164.425 115.705 199.439 1.00 94.92  ? 49  GLU L C   1 
ATOM 2536 O O   . GLU B 2 29  ? 164.567 115.134 200.525 1.00 94.92  ? 49  GLU L O   1 
ATOM 2537 C CB  . GLU B 2 29  ? 163.569 118.036 199.808 1.00 94.92  ? 49  GLU L CB  1 
ATOM 2538 C CG  . GLU B 2 29  ? 163.677 118.045 201.325 1.00 94.92  ? 49  GLU L CG  1 
ATOM 2539 C CD  . GLU B 2 29  ? 163.892 119.435 201.887 1.00 94.92  ? 49  GLU L CD  1 
ATOM 2540 O OE1 . GLU B 2 29  ? 163.931 120.399 201.094 1.00 94.92  ? 49  GLU L OE1 1 
ATOM 2541 O OE2 . GLU B 2 29  ? 164.021 119.565 203.123 1.00 94.92  ? 49  GLU L OE2 1 
ATOM 2542 N N   . THR B 2 30  ? 165.250 115.518 198.411 1.00 101.58 ? 50  THR L N   1 
ATOM 2543 C CA  . THR B 2 30  ? 166.428 114.664 198.500 1.00 101.58 ? 50  THR L CA  1 
ATOM 2544 C C   . THR B 2 30  ? 167.720 115.442 198.313 1.00 101.58 ? 50  THR L C   1 
ATOM 2545 O O   . THR B 2 30  ? 168.616 115.362 199.162 1.00 101.58 ? 50  THR L O   1 
ATOM 2546 C CB  . THR B 2 30  ? 166.344 113.533 197.462 1.00 101.58 ? 50  THR L CB  1 
ATOM 2547 O OG1 . THR B 2 30  ? 165.252 112.664 197.787 1.00 101.58 ? 50  THR L OG1 1 
ATOM 2548 C CG2 . THR B 2 30  ? 167.635 112.729 197.442 1.00 101.58 ? 50  THR L CG2 1 
ATOM 2549 N N   . SER B 2 31  ? 167.841 116.199 197.225 1.00 102.21 ? 51  SER L N   1 
ATOM 2550 C CA  . SER B 2 31  ? 169.003 117.051 196.977 1.00 102.21 ? 51  SER L CA  1 
ATOM 2551 C C   . SER B 2 31  ? 168.612 118.472 197.367 1.00 102.21 ? 51  SER L C   1 
ATOM 2552 O O   . SER B 2 31  ? 168.143 119.258 196.542 1.00 102.21 ? 51  SER L O   1 
ATOM 2553 C CB  . SER B 2 31  ? 169.447 116.959 195.521 1.00 102.21 ? 51  SER L CB  1 
ATOM 2554 O OG  . SER B 2 31  ? 169.514 115.610 195.093 1.00 102.21 ? 51  SER L OG  1 
ATOM 2555 N N   . VAL B 2 32  ? 168.807 118.800 198.646 1.00 97.05  ? 52  VAL L N   1 
ATOM 2556 C CA  . VAL B 2 32  ? 168.402 120.109 199.144 1.00 97.05  ? 52  VAL L CA  1 
ATOM 2557 C C   . VAL B 2 32  ? 169.313 121.194 198.577 1.00 97.05  ? 52  VAL L C   1 
ATOM 2558 O O   . VAL B 2 32  ? 170.461 120.954 198.184 1.00 97.05  ? 52  VAL L O   1 
ATOM 2559 C CB  . VAL B 2 32  ? 168.400 120.131 200.681 1.00 97.05  ? 52  VAL L CB  1 
ATOM 2560 C CG1 . VAL B 2 32  ? 167.417 119.105 201.223 1.00 97.05  ? 52  VAL L CG1 1 
ATOM 2561 C CG2 . VAL B 2 32  ? 169.800 119.872 201.218 1.00 97.05  ? 52  VAL L CG2 1 
ATOM 2562 N N   . GLU B 2 33  ? 168.781 122.414 198.535 1.00 88.93  ? 53  GLU L N   1 
ATOM 2563 C CA  . GLU B 2 33  ? 169.514 123.566 198.033 1.00 88.93  ? 53  GLU L CA  1 
ATOM 2564 C C   . GLU B 2 33  ? 168.929 124.823 198.665 1.00 88.93  ? 53  GLU L C   1 
ATOM 2565 O O   . GLU B 2 33  ? 167.837 124.803 199.241 1.00 88.93  ? 53  GLU L O   1 
ATOM 2566 C CB  . GLU B 2 33  ? 169.466 123.630 196.503 1.00 88.93  ? 53  GLU L CB  1 
ATOM 2567 N N   . SER B 2 34  ? 169.666 125.922 198.553 1.00 88.31  ? 54  SER L N   1 
ATOM 2568 C CA  . SER B 2 34  ? 169.272 127.189 199.142 1.00 88.31  ? 54  SER L CA  1 
ATOM 2569 C C   . SER B 2 34  ? 168.473 128.011 198.132 1.00 88.31  ? 54  SER L C   1 
ATOM 2570 O O   . SER B 2 34  ? 168.167 127.557 197.025 1.00 88.31  ? 54  SER L O   1 
ATOM 2571 C CB  . SER B 2 34  ? 170.510 127.942 199.635 1.00 88.31  ? 54  SER L CB  1 
ATOM 2572 N N   . ALA B 2 35  ? 168.128 129.238 198.515 1.00 90.83  ? 55  ALA L N   1 
ATOM 2573 C CA  . ALA B 2 35  ? 167.367 130.137 197.662 1.00 90.83  ? 55  ALA L CA  1 
ATOM 2574 C C   . ALA B 2 35  ? 167.938 131.541 197.808 1.00 90.83  ? 55  ALA L C   1 
ATOM 2575 O O   . ALA B 2 35  ? 168.843 131.785 198.610 1.00 90.83  ? 55  ALA L O   1 
ATOM 2576 C CB  . ALA B 2 35  ? 165.875 130.097 198.009 1.00 90.83  ? 55  ALA L CB  1 
ATOM 2577 N N   . VAL B 2 36  ? 167.398 132.473 197.021 1.00 92.01  ? 56  VAL L N   1 
ATOM 2578 C CA  . VAL B 2 36  ? 167.834 133.865 197.026 1.00 92.01  ? 56  VAL L CA  1 
ATOM 2579 C C   . VAL B 2 36  ? 166.687 134.810 197.372 1.00 92.01  ? 56  VAL L C   1 
ATOM 2580 O O   . VAL B 2 36  ? 166.855 135.738 198.171 1.00 92.01  ? 56  VAL L O   1 
ATOM 2581 C CB  . VAL B 2 36  ? 168.491 134.257 195.679 1.00 92.01  ? 56  VAL L CB  1 
ATOM 2582 C CG1 . VAL B 2 36  ? 167.536 134.049 194.507 1.00 92.01  ? 56  VAL L CG1 1 
ATOM 2583 C CG2 . VAL B 2 36  ? 168.983 135.697 195.725 1.00 92.01  ? 56  VAL L CG2 1 
ATOM 2584 N N   . ASP B 2 37  ? 165.509 134.588 196.778 1.00 89.20  ? 57  ASP L N   1 
ATOM 2585 C CA  . ASP B 2 37  ? 164.310 135.391 197.007 1.00 89.20  ? 57  ASP L CA  1 
ATOM 2586 C C   . ASP B 2 37  ? 164.492 136.842 196.569 1.00 89.20  ? 57  ASP L C   1 
ATOM 2587 O O   . ASP B 2 37  ? 165.614 137.295 196.322 1.00 89.20  ? 57  ASP L O   1 
ATOM 2588 C CB  . ASP B 2 37  ? 163.893 135.332 198.480 1.00 89.20  ? 57  ASP L CB  1 
ATOM 2589 N N   . THR B 2 38  ? 163.386 137.574 196.450 1.00 85.57  ? 58  THR L N   1 
ATOM 2590 C CA  . THR B 2 38  ? 163.431 138.991 196.110 1.00 85.57  ? 58  THR L CA  1 
ATOM 2591 C C   . THR B 2 38  ? 162.225 139.692 196.726 1.00 85.57  ? 58  THR L C   1 
ATOM 2592 O O   . THR B 2 38  ? 161.230 139.944 196.033 1.00 85.57  ? 58  THR L O   1 
ATOM 2593 C CB  . THR B 2 38  ? 163.456 139.194 194.592 1.00 85.57  ? 58  THR L CB  1 
ATOM 2594 O OG1 . THR B 2 38  ? 164.517 138.419 194.021 1.00 85.57  ? 58  THR L OG1 1 
ATOM 2595 C CG2 . THR B 2 38  ? 163.689 140.662 194.252 1.00 85.57  ? 58  THR L CG2 1 
ATOM 2596 N N   . PRO B 2 39  ? 162.261 140.003 198.022 1.00 85.14  ? 59  PRO L N   1 
ATOM 2597 C CA  . PRO B 2 39  ? 161.101 140.639 198.665 1.00 85.14  ? 59  PRO L CA  1 
ATOM 2598 C C   . PRO B 2 39  ? 161.021 142.117 198.313 1.00 85.14  ? 59  PRO L C   1 
ATOM 2599 O O   . PRO B 2 39  ? 161.784 142.934 198.834 1.00 85.14  ? 59  PRO L O   1 
ATOM 2600 C CB  . PRO B 2 39  ? 161.366 140.430 200.163 1.00 85.14  ? 59  PRO L CB  1 
ATOM 2601 C CG  . PRO B 2 39  ? 162.421 139.355 200.231 1.00 85.14  ? 59  PRO L CG  1 
ATOM 2602 C CD  . PRO B 2 39  ? 163.260 139.573 199.012 1.00 85.14  ? 59  PRO L CD  1 
ATOM 2603 N N   . PHE B 2 40  ? 160.085 142.458 197.428 1.00 83.33  ? 60  PHE L N   1 
ATOM 2604 C CA  . PHE B 2 40  ? 159.757 143.848 197.135 1.00 83.33  ? 60  PHE L CA  1 
ATOM 2605 C C   . PHE B 2 40  ? 158.371 143.913 196.492 1.00 83.33  ? 60  PHE L C   1 
ATOM 2606 O O   . PHE B 2 40  ? 157.495 144.606 197.024 1.00 83.33  ? 60  PHE L O   1 
ATOM 2607 C CB  . PHE B 2 40  ? 160.836 144.512 196.270 1.00 83.33  ? 60  PHE L CB  1 
ATOM 2608 N N   . PRO B 2 41  ? 158.107 143.221 195.352 1.00 85.63  ? 61  PRO L N   1 
ATOM 2609 C CA  . PRO B 2 41  ? 156.716 143.142 194.885 1.00 85.63  ? 61  PRO L CA  1 
ATOM 2610 C C   . PRO B 2 41  ? 155.866 142.326 195.843 1.00 85.63  ? 61  PRO L C   1 
ATOM 2611 O O   . PRO B 2 41  ? 156.215 141.180 196.149 1.00 85.63  ? 61  PRO L O   1 
ATOM 2612 C CB  . PRO B 2 41  ? 156.833 142.451 193.521 1.00 85.63  ? 61  PRO L CB  1 
ATOM 2613 C CG  . PRO B 2 41  ? 158.221 142.692 193.084 1.00 85.63  ? 61  PRO L CG  1 
ATOM 2614 C CD  . PRO B 2 41  ? 159.030 142.661 194.346 1.00 85.63  ? 61  PRO L CD  1 
ATOM 2615 N N   . ALA B 2 42  ? 154.778 142.916 196.349 1.00 87.54  ? 62  ALA L N   1 
ATOM 2616 C CA  . ALA B 2 42  ? 153.839 142.225 197.228 1.00 87.54  ? 62  ALA L CA  1 
ATOM 2617 C C   . ALA B 2 42  ? 154.501 141.882 198.557 1.00 87.54  ? 62  ALA L C   1 
ATOM 2618 O O   . ALA B 2 42  ? 155.617 142.333 198.835 1.00 87.54  ? 62  ALA L O   1 
ATOM 2619 C CB  . ALA B 2 42  ? 153.268 140.969 196.563 1.00 87.54  ? 62  ALA L CB  1 
ATOM 2620 N N   . GLY B 2 43  ? 153.807 141.107 199.393 1.00 88.09  ? 63  GLY L N   1 
ATOM 2621 C CA  . GLY B 2 43  ? 154.348 140.777 200.703 1.00 88.09  ? 63  GLY L CA  1 
ATOM 2622 C C   . GLY B 2 43  ? 155.668 140.032 200.631 1.00 88.09  ? 63  GLY L C   1 
ATOM 2623 O O   . GLY B 2 43  ? 156.619 140.362 201.343 1.00 88.09  ? 63  GLY L O   1 
ATOM 2624 N N   . ILE B 2 44  ? 155.746 139.016 199.773 1.00 88.13  ? 64  ILE L N   1 
ATOM 2625 C CA  . ILE B 2 44  ? 156.945 138.189 199.695 1.00 88.13  ? 64  ILE L CA  1 
ATOM 2626 C C   . ILE B 2 44  ? 157.125 137.618 198.295 1.00 88.13  ? 64  ILE L C   1 
ATOM 2627 O O   . ILE B 2 44  ? 156.218 137.688 197.458 1.00 88.13  ? 64  ILE L O   1 
ATOM 2628 C CB  . ILE B 2 44  ? 156.901 137.059 200.740 1.00 88.13  ? 64  ILE L CB  1 
ATOM 2629 N N   . PHE B 2 45  ? 158.301 137.048 198.039 1.00 85.51  ? 65  PHE L N   1 
ATOM 2630 C CA  . PHE B 2 45  ? 158.627 136.384 196.784 1.00 85.51  ? 65  PHE L CA  1 
ATOM 2631 C C   . PHE B 2 45  ? 159.888 135.561 196.998 1.00 85.51  ? 65  PHE L C   1 
ATOM 2632 O O   . PHE B 2 45  ? 160.849 136.048 197.598 1.00 85.51  ? 65  PHE L O   1 
ATOM 2633 C CB  . PHE B 2 45  ? 158.839 137.396 195.649 1.00 85.51  ? 65  PHE L CB  1 
ATOM 2634 C CG  . PHE B 2 45  ? 159.350 136.783 194.374 1.00 85.51  ? 65  PHE L CG  1 
ATOM 2635 C CD1 . PHE B 2 45  ? 158.493 136.098 193.528 1.00 85.51  ? 65  PHE L CD1 1 
ATOM 2636 C CD2 . PHE B 2 45  ? 160.687 136.886 194.024 1.00 85.51  ? 65  PHE L CD2 1 
ATOM 2637 C CE1 . PHE B 2 45  ? 158.958 135.531 192.356 1.00 85.51  ? 65  PHE L CE1 1 
ATOM 2638 C CE2 . PHE B 2 45  ? 161.158 136.320 192.853 1.00 85.51  ? 65  PHE L CE2 1 
ATOM 2639 C CZ  . PHE B 2 45  ? 160.291 135.642 192.018 1.00 85.51  ? 65  PHE L CZ  1 
ATOM 2640 N N   . VAL B 2 46  ? 159.879 134.321 196.512 1.00 85.60  ? 66  VAL L N   1 
ATOM 2641 C CA  . VAL B 2 46  ? 160.997 133.406 196.702 1.00 85.60  ? 66  VAL L CA  1 
ATOM 2642 C C   . VAL B 2 46  ? 161.358 132.757 195.374 1.00 85.60  ? 66  VAL L C   1 
ATOM 2643 O O   . VAL B 2 46  ? 160.530 132.651 194.464 1.00 85.60  ? 66  VAL L O   1 
ATOM 2644 C CB  . VAL B 2 46  ? 160.684 132.324 197.760 1.00 85.60  ? 66  VAL L CB  1 
ATOM 2645 C CG1 . VAL B 2 46  ? 160.535 132.950 199.139 1.00 85.60  ? 66  VAL L CG1 1 
ATOM 2646 C CG2 . VAL B 2 46  ? 159.430 131.554 197.377 1.00 85.60  ? 66  VAL L CG2 1 
ATOM 2647 N N   . ARG B 2 47  ? 162.615 132.324 195.269 1.00 85.33  ? 67  ARG L N   1 
ATOM 2648 C CA  . ARG B 2 47  ? 163.129 131.594 194.108 1.00 85.33  ? 67  ARG L CA  1 
ATOM 2649 C C   . ARG B 2 47  ? 163.960 130.429 194.640 1.00 85.33  ? 67  ARG L C   1 
ATOM 2650 O O   . ARG B 2 47  ? 165.168 130.564 194.853 1.00 85.33  ? 67  ARG L O   1 
ATOM 2651 C CB  . ARG B 2 47  ? 163.944 132.505 193.196 1.00 85.33  ? 67  ARG L CB  1 
ATOM 2652 N N   . LEU B 2 48  ? 163.312 129.287 194.850 1.00 88.41  ? 68  LEU L N   1 
ATOM 2653 C CA  . LEU B 2 48  ? 163.940 128.121 195.457 1.00 88.41  ? 68  LEU L CA  1 
ATOM 2654 C C   . LEU B 2 48  ? 163.897 126.945 194.492 1.00 88.41  ? 68  LEU L C   1 
ATOM 2655 O O   . LEU B 2 48  ? 162.871 126.702 193.846 1.00 88.41  ? 68  LEU L O   1 
ATOM 2656 C CB  . LEU B 2 48  ? 163.247 127.750 196.770 1.00 88.41  ? 68  LEU L CB  1 
ATOM 2657 N N   . GLU B 2 49  ? 165.009 126.221 194.397 1.00 90.09  ? 69  GLU L N   1 
ATOM 2658 C CA  . GLU B 2 49  ? 165.110 125.022 193.579 1.00 90.09  ? 69  GLU L CA  1 
ATOM 2659 C C   . GLU B 2 49  ? 165.632 123.871 194.429 1.00 90.09  ? 69  GLU L C   1 
ATOM 2660 O O   . GLU B 2 49  ? 166.491 124.067 195.296 1.00 90.09  ? 69  GLU L O   1 
ATOM 2661 C CB  . GLU B 2 49  ? 166.022 125.250 192.361 1.00 90.09  ? 69  GLU L CB  1 
ATOM 2662 C CG  . GLU B 2 49  ? 167.517 125.257 192.655 1.00 90.09  ? 69  GLU L CG  1 
ATOM 2663 C CD  . GLU B 2 49  ? 167.951 126.463 193.465 1.00 90.09  ? 69  GLU L CD  1 
ATOM 2664 O OE1 . GLU B 2 49  ? 167.328 127.535 193.319 1.00 90.09  ? 69  GLU L OE1 1 
ATOM 2665 O OE2 . GLU B 2 49  ? 168.917 126.338 194.247 1.00 90.09  ? 69  GLU L OE2 1 
ATOM 2666 N N   . PHE B 2 50  ? 165.095 122.677 194.191 1.00 94.96  ? 70  PHE L N   1 
ATOM 2667 C CA  . PHE B 2 50  ? 165.487 121.489 194.939 1.00 94.96  ? 70  PHE L CA  1 
ATOM 2668 C C   . PHE B 2 50  ? 164.915 120.261 194.249 1.00 94.96  ? 70  PHE L C   1 
ATOM 2669 O O   . PHE B 2 50  ? 163.871 120.333 193.593 1.00 94.96  ? 70  PHE L O   1 
ATOM 2670 C CB  . PHE B 2 50  ? 165.002 121.551 196.393 1.00 94.96  ? 70  PHE L CB  1 
ATOM 2671 N N   . LYS B 2 51  ? 165.608 119.139 194.405 1.00 98.19  ? 71  LYS L N   1 
ATOM 2672 C CA  . LYS B 2 51  ? 165.153 117.867 193.867 1.00 98.19  ? 71  LYS L CA  1 
ATOM 2673 C C   . LYS B 2 51  ? 164.199 117.187 194.844 1.00 98.19  ? 71  LYS L C   1 
ATOM 2674 O O   . LYS B 2 51  ? 164.131 117.527 196.027 1.00 98.19  ? 71  LYS L O   1 
ATOM 2675 C CB  . LYS B 2 51  ? 166.340 116.951 193.567 1.00 98.19  ? 71  LYS L CB  1 
ATOM 2676 N N   . LEU B 2 52  ? 163.457 116.214 194.329 1.00 102.94 ? 72  LEU L N   1 
ATOM 2677 C CA  . LEU B 2 52  ? 162.479 115.464 195.105 1.00 102.94 ? 72  LEU L CA  1 
ATOM 2678 C C   . LEU B 2 52  ? 162.901 113.999 195.182 1.00 102.94 ? 72  LEU L C   1 
ATOM 2679 O O   . LEU B 2 52  ? 163.847 113.563 194.522 1.00 102.94 ? 72  LEU L O   1 
ATOM 2680 C CB  . LEU B 2 52  ? 161.078 115.599 194.499 1.00 102.94 ? 72  LEU L CB  1 
ATOM 2681 C CG  . LEU B 2 52  ? 160.217 116.788 194.940 1.00 102.94 ? 72  LEU L CG  1 
ATOM 2682 C CD1 . LEU B 2 52  ? 159.968 116.747 196.441 1.00 102.94 ? 72  LEU L CD1 1 
ATOM 2683 C CD2 . LEU B 2 52  ? 160.831 118.120 194.527 1.00 102.94 ? 72  LEU L CD2 1 
ATOM 2684 N N   . GLN B 2 53  ? 162.182 113.236 196.001 1.00 103.36 ? 73  GLN L N   1 
ATOM 2685 C CA  . GLN B 2 53  ? 162.469 111.819 196.180 1.00 103.36 ? 73  GLN L CA  1 
ATOM 2686 C C   . GLN B 2 53  ? 161.810 111.019 195.057 1.00 103.36 ? 73  GLN L C   1 
ATOM 2687 O O   . GLN B 2 53  ? 161.214 111.573 194.129 1.00 103.36 ? 73  GLN L O   1 
ATOM 2688 C CB  . GLN B 2 53  ? 162.008 111.355 197.559 1.00 103.36 ? 73  GLN L CB  1 
ATOM 2689 N N   . GLN B 2 54  ? 161.912 109.695 195.134 1.00 106.41 ? 74  GLN L N   1 
ATOM 2690 C CA  . GLN B 2 54  ? 161.337 108.806 194.137 1.00 106.41 ? 74  GLN L CA  1 
ATOM 2691 C C   . GLN B 2 54  ? 160.484 107.750 194.824 1.00 106.41 ? 74  GLN L C   1 
ATOM 2692 O O   . GLN B 2 54  ? 160.863 107.202 195.863 1.00 106.41 ? 74  GLN L O   1 
ATOM 2693 C CB  . GLN B 2 54  ? 162.426 108.134 193.290 1.00 106.41 ? 74  GLN L CB  1 
ATOM 2694 C CG  . GLN B 2 54  ? 162.975 109.015 192.180 1.00 106.41 ? 74  GLN L CG  1 
ATOM 2695 C CD  . GLN B 2 54  ? 164.255 109.724 192.578 1.00 106.41 ? 74  GLN L CD  1 
ATOM 2696 O OE1 . GLN B 2 54  ? 164.521 109.933 193.761 1.00 106.41 ? 74  GLN L OE1 1 
ATOM 2697 N NE2 . GLN B 2 54  ? 165.055 110.100 191.587 1.00 106.41 ? 74  GLN L NE2 1 
ATOM 2698 N N   . THR B 2 55  ? 159.327 107.471 194.221 1.00 105.40 ? 75  THR L N   1 
ATOM 2699 C CA  . THR B 2 55  ? 158.335 106.511 194.725 1.00 105.40 ? 75  THR L CA  1 
ATOM 2700 C C   . THR B 2 55  ? 157.980 106.956 196.148 1.00 105.40 ? 75  THR L C   1 
ATOM 2701 O O   . THR B 2 55  ? 157.903 108.169 196.391 1.00 105.40 ? 75  THR L O   1 
ATOM 2702 C CB  . THR B 2 55  ? 158.897 105.095 194.570 1.00 105.40 ? 75  THR L CB  1 
ATOM 2703 O OG1 . THR B 2 55  ? 159.240 104.881 193.196 1.00 105.40 ? 75  THR L OG1 1 
ATOM 2704 C CG2 . THR B 2 55  ? 157.850 104.036 194.920 1.00 105.40 ? 75  THR L CG2 1 
ATOM 2705 N N   . SER B 2 56  ? 157.776 106.045 197.098 1.00 102.65 ? 76  SER L N   1 
ATOM 2706 C CA  . SER B 2 56  ? 157.466 106.366 198.486 1.00 102.65 ? 76  SER L CA  1 
ATOM 2707 C C   . SER B 2 56  ? 157.410 105.065 199.272 1.00 102.65 ? 76  SER L C   1 
ATOM 2708 O O   . SER B 2 56  ? 157.212 103.987 198.703 1.00 102.65 ? 76  SER L O   1 
ATOM 2709 C CB  . SER B 2 56  ? 156.137 107.118 198.626 1.00 102.65 ? 76  SER L CB  1 
ATOM 2710 O OG  . SER B 2 56  ? 155.708 107.147 199.976 1.00 102.65 ? 76  SER L OG  1 
ATOM 2711 N N   . CYS B 2 57  ? 157.588 105.179 200.589 1.00 104.30 ? 77  CYS L N   1 
ATOM 2712 C CA  . CYS B 2 57  ? 157.379 104.031 201.462 1.00 104.30 ? 77  CYS L CA  1 
ATOM 2713 C C   . CYS B 2 57  ? 155.898 103.770 201.702 1.00 104.30 ? 77  CYS L C   1 
ATOM 2714 O O   . CYS B 2 57  ? 155.493 102.613 201.860 1.00 104.30 ? 77  CYS L O   1 
ATOM 2715 C CB  . CYS B 2 57  ? 158.102 104.238 202.794 1.00 104.30 ? 77  CYS L CB  1 
ATOM 2716 S SG  . CYS B 2 57  ? 157.566 105.693 203.719 1.00 104.30 ? 77  CYS L SG  1 
ATOM 2717 N N   . ARG B 2 58  ? 155.085 104.824 201.732 1.00 105.00 ? 78  ARG L N   1 
ATOM 2718 C CA  . ARG B 2 58  ? 153.647 104.696 201.913 1.00 105.00 ? 78  ARG L CA  1 
ATOM 2719 C C   . ARG B 2 58  ? 152.950 105.716 201.025 1.00 105.00 ? 78  ARG L C   1 
ATOM 2720 O O   . ARG B 2 58  ? 153.522 106.754 200.682 1.00 105.00 ? 78  ARG L O   1 
ATOM 2721 C CB  . ARG B 2 58  ? 153.241 104.895 203.378 1.00 105.00 ? 78  ARG L CB  1 
ATOM 2722 N N   . LYS B 2 59  ? 151.710 105.412 200.659 1.00 106.38 ? 79  LYS L N   1 
ATOM 2723 C CA  . LYS B 2 59  ? 150.928 106.257 199.770 1.00 106.38 ? 79  LYS L CA  1 
ATOM 2724 C C   . LYS B 2 59  ? 149.931 107.093 200.562 1.00 106.38 ? 79  LYS L C   1 
ATOM 2725 O O   . LYS B 2 59  ? 149.371 106.642 201.565 1.00 106.38 ? 79  LYS L O   1 
ATOM 2726 C CB  . LYS B 2 59  ? 150.188 105.414 198.730 1.00 106.38 ? 79  LYS L CB  1 
ATOM 2727 N N   . ARG B 2 60  ? 149.715 108.324 200.091 1.00 108.64 ? 80  ARG L N   1 
ATOM 2728 C CA  . ARG B 2 60  ? 148.772 109.261 200.706 1.00 108.64 ? 80  ARG L CA  1 
ATOM 2729 C C   . ARG B 2 60  ? 149.084 109.481 202.185 1.00 108.64 ? 80  ARG L C   1 
ATOM 2730 O O   . ARG B 2 60  ? 148.189 109.503 203.032 1.00 108.64 ? 80  ARG L O   1 
ATOM 2731 C CB  . ARG B 2 60  ? 147.327 108.793 200.519 1.00 108.64 ? 80  ARG L CB  1 
ATOM 2732 N N   . ASP B 2 61  ? 150.369 109.645 202.500 1.00 106.72 ? 81  ASP L N   1 
ATOM 2733 C CA  . ASP B 2 61  ? 150.807 109.870 203.878 1.00 106.72 ? 81  ASP L CA  1 
ATOM 2734 C C   . ASP B 2 61  ? 150.826 111.373 204.164 1.00 106.72 ? 81  ASP L C   1 
ATOM 2735 O O   . ASP B 2 61  ? 151.856 111.972 204.482 1.00 106.72 ? 81  ASP L O   1 
ATOM 2736 C CB  . ASP B 2 61  ? 152.170 109.232 204.113 1.00 106.72 ? 81  ASP L CB  1 
ATOM 2737 C CG  . ASP B 2 61  ? 152.513 109.106 205.587 1.00 106.72 ? 81  ASP L CG  1 
ATOM 2738 O OD1 . ASP B 2 61  ? 151.788 109.682 206.426 1.00 106.72 ? 81  ASP L OD1 1 
ATOM 2739 O OD2 . ASP B 2 61  ? 153.512 108.428 205.908 1.00 106.72 ? 81  ASP L OD2 1 
ATOM 2740 N N   . TRP B 2 62  ? 149.641 111.978 204.027 1.00 106.72 ? 82  TRP L N   1 
ATOM 2741 C CA  . TRP B 2 62  ? 149.413 113.397 204.293 1.00 106.72 ? 82  TRP L CA  1 
ATOM 2742 C C   . TRP B 2 62  ? 150.173 114.291 203.319 1.00 106.72 ? 82  TRP L C   1 
ATOM 2743 O O   . TRP B 2 62  ? 151.089 113.836 202.625 1.00 106.72 ? 82  TRP L O   1 
ATOM 2744 C CB  . TRP B 2 62  ? 149.786 113.747 205.737 1.00 106.72 ? 82  TRP L CB  1 
ATOM 2745 N N   . LYS B 2 63  ? 149.780 115.565 203.244 1.00 105.01 ? 83  LYS L N   1 
ATOM 2746 C CA  . LYS B 2 63  ? 150.490 116.505 202.382 1.00 105.01 ? 83  LYS L CA  1 
ATOM 2747 C C   . LYS B 2 63  ? 151.942 116.669 202.813 1.00 105.01 ? 83  LYS L C   1 
ATOM 2748 O O   . LYS B 2 63  ? 152.842 116.690 201.966 1.00 105.01 ? 83  LYS L O   1 
ATOM 2749 C CB  . LYS B 2 63  ? 149.779 117.858 202.380 1.00 105.01 ? 83  LYS L CB  1 
ATOM 2750 N N   . LYS B 2 64  ? 152.191 116.786 204.129 1.00 107.40 ? 84  LYS L N   1 
ATOM 2751 C CA  . LYS B 2 64  ? 153.545 116.867 204.652 1.00 107.40 ? 84  LYS L CA  1 
ATOM 2752 C C   . LYS B 2 64  ? 154.244 115.516 204.537 1.00 107.40 ? 84  LYS L C   1 
ATOM 2753 O O   . LYS B 2 64  ? 153.603 114.466 204.655 1.00 107.40 ? 84  LYS L O   1 
ATOM 2754 C CB  . LYS B 2 64  ? 153.526 117.312 206.112 1.00 107.40 ? 84  LYS L CB  1 
ATOM 2755 N N   . PRO B 2 65  ? 155.559 115.507 204.307 1.00 107.22 ? 85  PRO L N   1 
ATOM 2756 C CA  . PRO B 2 65  ? 156.268 114.231 204.165 1.00 107.22 ? 85  PRO L CA  1 
ATOM 2757 C C   . PRO B 2 65  ? 156.676 113.636 205.504 1.00 107.22 ? 85  PRO L C   1 
ATOM 2758 O O   . PRO B 2 65  ? 157.409 114.261 206.276 1.00 107.22 ? 85  PRO L O   1 
ATOM 2759 C CB  . PRO B 2 65  ? 157.488 114.608 203.317 1.00 107.22 ? 85  PRO L CB  1 
ATOM 2760 C CG  . PRO B 2 65  ? 157.758 116.043 203.671 1.00 107.22 ? 85  PRO L CG  1 
ATOM 2761 C CD  . PRO B 2 65  ? 156.464 116.661 204.165 1.00 107.22 ? 85  PRO L CD  1 
ATOM 2762 N N   . GLU B 2 66  ? 156.201 112.424 205.788 1.00 104.48 ? 86  GLU L N   1 
ATOM 2763 C CA  . GLU B 2 66  ? 156.539 111.718 207.016 1.00 104.48 ? 86  GLU L CA  1 
ATOM 2764 C C   . GLU B 2 66  ? 157.467 110.535 206.771 1.00 104.48 ? 86  GLU L C   1 
ATOM 2765 O O   . GLU B 2 66  ? 157.741 109.771 207.702 1.00 104.48 ? 86  GLU L O   1 
ATOM 2766 C CB  . GLU B 2 66  ? 155.265 111.248 207.723 1.00 104.48 ? 86  GLU L CB  1 
ATOM 2767 N N   . CYS B 2 67  ? 157.956 110.367 205.545 1.00 98.80  ? 87  CYS L N   1 
ATOM 2768 C CA  . CYS B 2 67  ? 158.832 109.255 205.187 1.00 98.80  ? 87  CYS L CA  1 
ATOM 2769 C C   . CYS B 2 67  ? 160.254 109.795 205.070 1.00 98.80  ? 87  CYS L C   1 
ATOM 2770 O O   . CYS B 2 67  ? 160.597 110.467 204.094 1.00 98.80  ? 87  CYS L O   1 
ATOM 2771 C CB  . CYS B 2 67  ? 158.368 108.601 203.889 1.00 98.80  ? 87  CYS L CB  1 
ATOM 2772 S SG  . CYS B 2 67  ? 159.116 106.994 203.547 1.00 98.80  ? 87  CYS L SG  1 
ATOM 2773 N N   . LYS B 2 68  ? 161.081 109.501 206.076 1.00 92.80  ? 88  LYS L N   1 
ATOM 2774 C CA  . LYS B 2 68  ? 162.454 109.996 206.078 1.00 92.80  ? 88  LYS L CA  1 
ATOM 2775 C C   . LYS B 2 68  ? 163.267 109.390 204.940 1.00 92.80  ? 88  LYS L C   1 
ATOM 2776 O O   . LYS B 2 68  ? 164.058 110.087 204.293 1.00 92.80  ? 88  LYS L O   1 
ATOM 2777 C CB  . LYS B 2 68  ? 163.115 109.703 207.425 1.00 92.80  ? 88  LYS L CB  1 
ATOM 2778 N N   . VAL B 2 69  ? 163.088 108.099 204.682 1.00 89.85  ? 89  VAL L N   1 
ATOM 2779 C CA  . VAL B 2 69  ? 163.855 107.394 203.661 1.00 89.85  ? 89  VAL L CA  1 
ATOM 2780 C C   . VAL B 2 69  ? 163.168 107.574 202.314 1.00 89.85  ? 89  VAL L C   1 
ATOM 2781 O O   . VAL B 2 69  ? 161.973 107.292 202.171 1.00 89.85  ? 89  VAL L O   1 
ATOM 2782 C CB  . VAL B 2 69  ? 163.999 105.905 204.013 1.00 89.85  ? 89  VAL L CB  1 
ATOM 2783 C CG1 . VAL B 2 69  ? 164.542 105.126 202.824 1.00 89.85  ? 89  VAL L CG1 1 
ATOM 2784 C CG2 . VAL B 2 69  ? 164.899 105.733 205.227 1.00 89.85  ? 89  VAL L CG2 1 
ATOM 2785 N N   . ARG B 2 70  ? 163.924 108.042 201.325 1.00 85.98  ? 90  ARG L N   1 
ATOM 2786 C CA  . ARG B 2 70  ? 163.392 108.254 199.984 1.00 85.98  ? 90  ARG L CA  1 
ATOM 2787 C C   . ARG B 2 70  ? 163.060 106.928 199.307 1.00 85.98  ? 90  ARG L C   1 
ATOM 2788 O O   . ARG B 2 70  ? 163.893 106.349 198.611 1.00 85.98  ? 90  ARG L O   1 
ATOM 2789 C CB  . ARG B 2 70  ? 164.388 109.044 199.132 1.00 85.98  ? 90  ARG L CB  1 
ATOM 2790 N N   . LYS B 2 77  ? 166.570 119.760 190.103 1.00 98.50  ? 97  LYS L N   1 
ATOM 2791 C CA  . LYS B 2 77  ? 166.589 121.189 189.814 1.00 98.50  ? 97  LYS L CA  1 
ATOM 2792 C C   . LYS B 2 77  ? 165.192 121.697 189.473 1.00 98.50  ? 97  LYS L C   1 
ATOM 2793 O O   . LYS B 2 77  ? 164.762 121.634 188.321 1.00 98.50  ? 97  LYS L O   1 
ATOM 2794 C CB  . LYS B 2 77  ? 167.554 121.492 188.666 1.00 98.50  ? 97  LYS L CB  1 
ATOM 2795 N N   . CYS B 2 78  ? 164.487 122.199 190.482 1.00 101.52 ? 98  CYS L N   1 
ATOM 2796 C CA  . CYS B 2 78  ? 163.139 122.713 190.303 1.00 101.52 ? 98  CYS L CA  1 
ATOM 2797 C C   . CYS B 2 78  ? 163.193 124.214 190.018 1.00 101.52 ? 98  CYS L C   1 
ATOM 2798 O O   . CYS B 2 78  ? 164.257 124.785 189.763 1.00 101.52 ? 98  CYS L O   1 
ATOM 2799 C CB  . CYS B 2 78  ? 162.285 122.394 191.528 1.00 101.52 ? 98  CYS L CB  1 
ATOM 2800 S SG  . CYS B 2 78  ? 160.537 122.824 191.349 1.00 101.52 ? 98  CYS L SG  1 
ATOM 2801 N N   . LEU B 2 79  ? 162.033 124.868 190.048 1.00 91.75  ? 99  LEU L N   1 
ATOM 2802 C CA  . LEU B 2 79  ? 161.962 126.312 189.831 1.00 91.75  ? 99  LEU L CA  1 
ATOM 2803 C C   . LEU B 2 79  ? 160.668 126.811 190.458 1.00 91.75  ? 99  LEU L C   1 
ATOM 2804 O O   . LEU B 2 79  ? 159.581 126.461 189.990 1.00 91.75  ? 99  LEU L O   1 
ATOM 2805 C CB  . LEU B 2 79  ? 162.021 126.645 188.345 1.00 91.75  ? 99  LEU L CB  1 
ATOM 2806 N N   . ALA B 2 80  ? 160.786 127.621 191.507 1.00 83.55  ? 100 ALA L N   1 
ATOM 2807 C CA  . ALA B 2 80  ? 159.637 128.149 192.228 1.00 83.55  ? 100 ALA L CA  1 
ATOM 2808 C C   . ALA B 2 80  ? 159.654 129.668 192.173 1.00 83.55  ? 100 ALA L C   1 
ATOM 2809 O O   . ALA B 2 80  ? 160.661 130.295 192.519 1.00 83.55  ? 100 ALA L O   1 
ATOM 2810 C CB  . ALA B 2 80  ? 159.634 127.672 193.682 1.00 83.55  ? 100 ALA L CB  1 
ATOM 2811 N N   . CYS B 2 81  ? 158.539 130.255 191.734 1.00 82.96  ? 101 CYS L N   1 
ATOM 2812 C CA  . CYS B 2 81  ? 158.359 131.710 191.714 1.00 82.96  ? 101 CYS L CA  1 
ATOM 2813 C C   . CYS B 2 81  ? 156.923 131.982 192.159 1.00 82.96  ? 101 CYS L C   1 
ATOM 2814 O O   . CYS B 2 81  ? 156.001 131.998 191.339 1.00 82.96  ? 101 CYS L O   1 
ATOM 2815 C CB  . CYS B 2 81  ? 158.647 132.294 190.335 1.00 82.96  ? 101 CYS L CB  1 
ATOM 2816 S SG  . CYS B 2 81  ? 160.285 131.913 189.668 1.00 82.96  ? 101 CYS L SG  1 
ATOM 2817 N N   . ILE B 2 82  ? 156.737 132.199 193.461 1.00 79.65  ? 102 ILE L N   1 
ATOM 2818 C CA  . ILE B 2 82  ? 155.413 132.426 194.022 1.00 79.65  ? 102 ILE L CA  1 
ATOM 2819 C C   . ILE B 2 82  ? 155.399 133.779 194.719 1.00 79.65  ? 102 ILE L C   1 
ATOM 2820 O O   . ILE B 2 82  ? 156.441 134.353 195.040 1.00 79.65  ? 102 ILE L O   1 
ATOM 2821 C CB  . ILE B 2 82  ? 154.988 131.323 195.012 1.00 79.65  ? 102 ILE L CB  1 
ATOM 2822 C CG1 . ILE B 2 82  ? 155.808 131.419 196.296 1.00 79.65  ? 102 ILE L CG1 1 
ATOM 2823 C CG2 . ILE B 2 82  ? 155.159 129.949 194.389 1.00 79.65  ? 102 ILE L CG2 1 
ATOM 2824 C CD1 . ILE B 2 82  ? 155.267 130.574 197.417 1.00 79.65  ? 102 ILE L CD1 1 
ATOM 2825 N N   . LYS B 2 83  ? 154.192 134.278 194.957 1.00 80.14  ? 103 LYS L N   1 
ATOM 2826 C CA  . LYS B 2 83  ? 154.002 135.566 195.612 1.00 80.14  ? 103 LYS L CA  1 
ATOM 2827 C C   . LYS B 2 83  ? 153.740 135.395 197.105 1.00 80.14  ? 103 LYS L C   1 
ATOM 2828 O O   . LYS B 2 83  ? 154.666 135.195 197.890 1.00 80.14  ? 103 LYS L O   1 
ATOM 2829 C CB  . LYS B 2 83  ? 152.844 136.330 194.957 1.00 80.14  ? 103 LYS L CB  1 
ATOM 2830 C CG  . LYS B 2 83  ? 153.134 136.977 193.589 1.00 80.14  ? 103 LYS L CG  1 
ATOM 2831 C CD  . LYS B 2 83  ? 154.527 137.604 193.406 1.00 80.14  ? 103 LYS L CD  1 
ATOM 2832 C CE  . LYS B 2 83  ? 154.940 138.547 194.537 1.00 80.14  ? 103 LYS L CE  1 
ATOM 2833 N NZ  . LYS B 2 83  ? 156.261 139.181 194.281 1.00 80.14  ? 103 LYS L NZ  1 
ATOM 2834 N N   . LYS B 2 89  ? 148.002 132.144 201.130 1.00 58.94  ? 109 LYS L N   1 
ATOM 2835 C CA  . LYS B 2 89  ? 148.477 133.520 201.051 1.00 58.94  ? 109 LYS L CA  1 
ATOM 2836 C C   . LYS B 2 89  ? 149.273 133.751 199.771 1.00 58.94  ? 109 LYS L C   1 
ATOM 2837 O O   . LYS B 2 89  ? 150.039 134.710 199.670 1.00 58.94  ? 109 LYS L O   1 
ATOM 2838 C CB  . LYS B 2 89  ? 149.331 133.864 202.273 1.00 58.94  ? 109 LYS L CB  1 
ATOM 2839 N N   . VAL B 2 90  ? 149.087 132.867 198.796 1.00 61.80  ? 110 VAL L N   1 
ATOM 2840 C CA  . VAL B 2 90  ? 149.769 132.945 197.509 1.00 61.80  ? 110 VAL L CA  1 
ATOM 2841 C C   . VAL B 2 90  ? 148.721 133.217 196.439 1.00 61.80  ? 110 VAL L C   1 
ATOM 2842 O O   . VAL B 2 90  ? 147.737 132.476 196.319 1.00 61.80  ? 110 VAL L O   1 
ATOM 2843 C CB  . VAL B 2 90  ? 150.552 131.660 197.201 1.00 61.80  ? 110 VAL L CB  1 
ATOM 2844 N N   . LEU B 2 91  ? 148.932 134.277 195.663 1.00 67.01  ? 111 LEU L N   1 
ATOM 2845 C CA  . LEU B 2 91  ? 148.010 134.662 194.603 1.00 67.01  ? 111 LEU L CA  1 
ATOM 2846 C C   . LEU B 2 91  ? 148.370 134.056 193.253 1.00 67.01  ? 111 LEU L C   1 
ATOM 2847 O O   . LEU B 2 91  ? 147.650 134.287 192.276 1.00 67.01  ? 111 LEU L O   1 
ATOM 2848 C CB  . LEU B 2 91  ? 147.954 136.188 194.483 1.00 67.01  ? 111 LEU L CB  1 
ATOM 2849 N N   . GLY B 2 92  ? 149.457 133.293 193.172 1.00 68.08  ? 112 GLY L N   1 
ATOM 2850 C CA  . GLY B 2 92  ? 149.858 132.678 191.923 1.00 68.08  ? 112 GLY L CA  1 
ATOM 2851 C C   . GLY B 2 92  ? 151.137 131.876 192.039 1.00 68.08  ? 112 GLY L C   1 
ATOM 2852 O O   . GLY B 2 92  ? 152.087 132.304 192.702 1.00 68.08  ? 112 GLY L O   1 
ATOM 2853 N N   . ARG B 2 93  ? 151.175 130.710 191.398 1.00 74.23  ? 113 ARG L N   1 
ATOM 2854 C CA  . ARG B 2 93  ? 152.346 129.848 191.445 1.00 74.23  ? 113 ARG L CA  1 
ATOM 2855 C C   . ARG B 2 93  ? 152.484 129.119 190.118 1.00 74.23  ? 113 ARG L C   1 
ATOM 2856 O O   . ARG B 2 93  ? 151.487 128.695 189.528 1.00 74.23  ? 113 ARG L O   1 
ATOM 2857 C CB  . ARG B 2 93  ? 152.252 128.841 192.597 1.00 74.23  ? 113 ARG L CB  1 
ATOM 2858 C CG  . ARG B 2 93  ? 150.902 128.154 192.723 1.00 74.23  ? 113 ARG L CG  1 
ATOM 2859 C CD  . ARG B 2 93  ? 151.064 126.713 193.178 1.00 74.23  ? 113 ARG L CD  1 
ATOM 2860 N NE  . ARG B 2 93  ? 149.816 125.965 193.095 1.00 74.23  ? 113 ARG L NE  1 
ATOM 2861 C CZ  . ARG B 2 93  ? 149.440 125.248 192.045 1.00 74.23  ? 113 ARG L CZ  1 
ATOM 2862 N NH1 . ARG B 2 93  ? 150.194 125.163 190.961 1.00 74.23  ? 113 ARG L NH1 1 
ATOM 2863 N NH2 . ARG B 2 93  ? 148.279 124.600 192.082 1.00 74.23  ? 113 ARG L NH2 1 
ATOM 2864 N N   . LEU B 2 94  ? 153.727 128.977 189.653 1.00 80.17  ? 114 LEU L N   1 
ATOM 2865 C CA  . LEU B 2 94  ? 154.019 128.258 188.418 1.00 80.17  ? 114 LEU L CA  1 
ATOM 2866 C C   . LEU B 2 94  ? 155.071 127.179 188.648 1.00 80.17  ? 114 LEU L C   1 
ATOM 2867 O O   . LEU B 2 94  ? 155.837 126.844 187.739 1.00 80.17  ? 114 LEU L O   1 
ATOM 2868 C CB  . LEU B 2 94  ? 154.458 129.217 187.307 1.00 80.17  ? 114 LEU L CB  1 
ATOM 2869 C CG  . LEU B 2 94  ? 155.848 129.863 187.331 1.00 80.17  ? 114 LEU L CG  1 
ATOM 2870 C CD1 . LEU B 2 94  ? 156.186 130.428 185.962 1.00 80.17  ? 114 LEU L CD1 1 
ATOM 2871 C CD2 . LEU B 2 94  ? 155.945 130.943 188.385 1.00 80.17  ? 114 LEU L CD2 1 
ATOM 2872 N N   . VAL B 2 95  ? 155.110 126.617 189.859 1.00 86.15  ? 115 VAL L N   1 
ATOM 2873 C CA  . VAL B 2 95  ? 156.073 125.567 190.167 1.00 86.15  ? 115 VAL L CA  1 
ATOM 2874 C C   . VAL B 2 95  ? 155.885 124.406 189.202 1.00 86.15  ? 115 VAL L C   1 
ATOM 2875 O O   . VAL B 2 95  ? 154.770 123.903 189.013 1.00 86.15  ? 115 VAL L O   1 
ATOM 2876 C CB  . VAL B 2 95  ? 155.930 125.120 191.630 1.00 86.15  ? 115 VAL L CB  1 
ATOM 2877 C CG1 . VAL B 2 95  ? 156.491 126.179 192.560 1.00 86.15  ? 115 VAL L CG1 1 
ATOM 2878 C CG2 . VAL B 2 95  ? 154.471 124.845 191.968 1.00 86.15  ? 115 VAL L CG2 1 
ATOM 2879 N N   . HIS B 2 96  ? 156.977 123.993 188.561 1.00 93.33  ? 116 HIS L N   1 
ATOM 2880 C CA  . HIS B 2 96  ? 156.909 122.938 187.558 1.00 93.33  ? 116 HIS L CA  1 
ATOM 2881 C C   . HIS B 2 96  ? 157.940 121.850 187.830 1.00 93.33  ? 116 HIS L C   1 
ATOM 2882 O O   . HIS B 2 96  ? 157.718 120.683 187.489 1.00 93.33  ? 116 HIS L O   1 
ATOM 2883 C CB  . HIS B 2 96  ? 157.100 123.527 186.157 1.00 93.33  ? 116 HIS L CB  1 
ATOM 2884 C CG  . HIS B 2 96  ? 158.495 123.994 185.878 1.00 93.33  ? 116 HIS L CG  1 
ATOM 2885 N ND1 . HIS B 2 96  ? 158.881 125.310 186.016 1.00 93.33  ? 116 HIS L ND1 1 
ATOM 2886 C CD2 . HIS B 2 96  ? 159.593 123.323 185.456 1.00 93.33  ? 116 HIS L CD2 1 
ATOM 2887 C CE1 . HIS B 2 96  ? 160.157 125.428 185.698 1.00 93.33  ? 116 HIS L CE1 1 
ATOM 2888 N NE2 . HIS B 2 96  ? 160.614 124.237 185.356 1.00 93.33  ? 116 HIS L NE2 1 
ATOM 2889 N N   . CYS B 2 97  ? 159.060 122.225 188.444 1.00 98.05  ? 117 CYS L N   1 
ATOM 2890 C CA  . CYS B 2 97  ? 160.150 121.299 188.748 1.00 98.05  ? 117 CYS L CA  1 
ATOM 2891 C C   . CYS B 2 97  ? 160.617 120.537 187.510 1.00 98.05  ? 117 CYS L C   1 
ATOM 2892 O O   . CYS B 2 97  ? 161.692 119.938 187.507 1.00 98.05  ? 117 CYS L O   1 
ATOM 2893 C CB  . CYS B 2 97  ? 159.730 120.314 189.843 1.00 98.05  ? 117 CYS L CB  1 
ATOM 2894 S SG  . CYS B 2 97  ? 159.565 121.046 191.488 1.00 98.05  ? 117 CYS L SG  1 
ATOM 2895 N N   . THR B 2 113 ? 160.495 129.409 181.590 1.00 79.07  ? 133 THR L N   1 
ATOM 2896 C CA  . THR B 2 113 ? 159.736 129.836 182.760 1.00 79.07  ? 133 THR L CA  1 
ATOM 2897 C C   . THR B 2 113 ? 159.061 131.181 182.513 1.00 79.07  ? 133 THR L C   1 
ATOM 2898 O O   . THR B 2 113 ? 159.413 131.902 181.580 1.00 79.07  ? 133 THR L O   1 
ATOM 2899 C CB  . THR B 2 113 ? 160.632 129.940 184.008 1.00 79.07  ? 133 THR L CB  1 
ATOM 2900 O OG1 . THR B 2 113 ? 159.824 130.219 185.158 1.00 79.07  ? 133 THR L OG1 1 
ATOM 2901 C CG2 . THR B 2 113 ? 161.661 131.047 183.835 1.00 79.07  ? 133 THR L CG2 1 
ATOM 2902 N N   . GLN B 2 114 ? 158.085 131.512 183.356 1.00 74.96  ? 134 GLN L N   1 
ATOM 2903 C CA  . GLN B 2 114 ? 157.338 132.760 183.260 1.00 74.96  ? 134 GLN L CA  1 
ATOM 2904 C C   . GLN B 2 114 ? 157.281 133.455 184.612 1.00 74.96  ? 134 GLN L C   1 
ATOM 2905 O O   . GLN B 2 114 ? 156.238 133.967 185.026 1.00 74.96  ? 134 GLN L O   1 
ATOM 2906 C CB  . GLN B 2 114 ? 155.930 132.517 182.722 1.00 74.96  ? 134 GLN L CB  1 
ATOM 2907 C CG  . GLN B 2 114 ? 155.893 131.804 181.383 1.00 74.96  ? 134 GLN L CG  1 
ATOM 2908 C CD  . GLN B 2 114 ? 154.897 132.420 180.423 1.00 74.96  ? 134 GLN L CD  1 
ATOM 2909 O OE1 . GLN B 2 114 ? 154.629 133.620 180.473 1.00 74.96  ? 134 GLN L OE1 1 
ATOM 2910 N NE2 . GLN B 2 114 ? 154.344 131.600 179.540 1.00 74.96  ? 134 GLN L NE2 1 
ATOM 2911 N N   . CYS B 2 115 ? 158.411 133.480 185.323 1.00 78.38  ? 135 CYS L N   1 
ATOM 2912 C CA  . CYS B 2 115 ? 158.453 134.114 186.635 1.00 78.38  ? 135 CYS L CA  1 
ATOM 2913 C C   . CYS B 2 115 ? 158.275 135.624 186.561 1.00 78.38  ? 135 CYS L C   1 
ATOM 2914 O O   . CYS B 2 115 ? 157.924 136.242 187.572 1.00 78.38  ? 135 CYS L O   1 
ATOM 2915 C CB  . CYS B 2 115 ? 159.772 133.784 187.337 1.00 78.38  ? 135 CYS L CB  1 
ATOM 2916 S SG  . CYS B 2 115 ? 160.040 132.024 187.654 1.00 78.38  ? 135 CYS L SG  1 
ATOM 2917 N N   . LEU B 2 116 ? 158.499 136.228 185.391 1.00 76.93  ? 136 LEU L N   1 
ATOM 2918 C CA  . LEU B 2 116 ? 158.450 137.683 185.278 1.00 76.93  ? 136 LEU L CA  1 
ATOM 2919 C C   . LEU B 2 116 ? 157.061 138.220 185.604 1.00 76.93  ? 136 LEU L C   1 
ATOM 2920 O O   . LEU B 2 116 ? 156.910 139.115 186.444 1.00 76.93  ? 136 LEU L O   1 
ATOM 2921 C CB  . LEU B 2 116 ? 158.875 138.114 183.873 1.00 76.93  ? 136 LEU L CB  1 
ATOM 2922 C CG  . LEU B 2 116 ? 160.374 138.189 183.568 1.00 76.93  ? 136 LEU L CG  1 
ATOM 2923 C CD1 . LEU B 2 116 ? 160.976 136.802 183.384 1.00 76.93  ? 136 LEU L CD1 1 
ATOM 2924 C CD2 . LEU B 2 116 ? 160.625 139.049 182.339 1.00 76.93  ? 136 LEU L CD2 1 
ATOM 2925 N N   . ARG B 2 117 ? 156.030 137.680 184.952 1.00 72.12  ? 137 ARG L N   1 
ATOM 2926 C CA  . ARG B 2 117 ? 154.676 138.169 185.183 1.00 72.12  ? 137 ARG L CA  1 
ATOM 2927 C C   . ARG B 2 117 ? 154.113 137.698 186.518 1.00 72.12  ? 137 ARG L C   1 
ATOM 2928 O O   . ARG B 2 117 ? 153.304 138.407 187.126 1.00 72.12  ? 137 ARG L O   1 
ATOM 2929 C CB  . ARG B 2 117 ? 153.756 137.740 184.039 1.00 72.12  ? 137 ARG L CB  1 
ATOM 2930 C CG  . ARG B 2 117 ? 153.787 136.254 183.730 1.00 72.12  ? 137 ARG L CG  1 
ATOM 2931 C CD  . ARG B 2 117 ? 153.338 135.995 182.302 1.00 72.12  ? 137 ARG L CD  1 
ATOM 2932 N NE  . ARG B 2 117 ? 152.310 136.938 181.879 1.00 72.12  ? 137 ARG L NE  1 
ATOM 2933 C CZ  . ARG B 2 117 ? 152.121 137.329 180.626 1.00 72.12  ? 137 ARG L CZ  1 
ATOM 2934 N NH1 . ARG B 2 117 ? 152.879 136.880 179.639 1.00 72.12  ? 137 ARG L NH1 1 
ATOM 2935 N NH2 . ARG B 2 117 ? 151.145 138.192 180.357 1.00 72.12  ? 137 ARG L NH2 1 
ATOM 2936 N N   . VAL B 2 118 ? 154.518 136.515 186.983 1.00 77.24  ? 138 VAL L N   1 
ATOM 2937 C CA  . VAL B 2 118 ? 154.055 136.035 188.281 1.00 77.24  ? 138 VAL L CA  1 
ATOM 2938 C C   . VAL B 2 118 ? 154.590 136.919 189.399 1.00 77.24  ? 138 VAL L C   1 
ATOM 2939 O O   . VAL B 2 118 ? 153.861 137.265 190.337 1.00 77.24  ? 138 VAL L O   1 
ATOM 2940 C CB  . VAL B 2 118 ? 154.451 134.562 188.479 1.00 77.24  ? 138 VAL L CB  1 
ATOM 2941 C CG1 . VAL B 2 118 ? 153.914 134.043 189.803 1.00 77.24  ? 138 VAL L CG1 1 
ATOM 2942 C CG2 . VAL B 2 118 ? 153.929 133.721 187.327 1.00 77.24  ? 138 VAL L CG2 1 
ATOM 2943 N N   . GLN B 2 119 ? 155.866 137.307 189.318 1.00 80.60  ? 139 GLN L N   1 
ATOM 2944 C CA  . GLN B 2 119 ? 156.434 138.193 190.329 1.00 80.60  ? 139 GLN L CA  1 
ATOM 2945 C C   . GLN B 2 119 ? 155.796 139.575 190.288 1.00 80.60  ? 139 GLN L C   1 
ATOM 2946 O O   . GLN B 2 119 ? 155.766 140.273 191.308 1.00 80.60  ? 139 GLN L O   1 
ATOM 2947 C CB  . GLN B 2 119 ? 157.948 138.300 190.142 1.00 80.60  ? 139 GLN L CB  1 
ATOM 2948 N N   . ARG B 2 120 ? 155.285 139.986 189.130 1.00 79.68  ? 140 ARG L N   1 
ATOM 2949 C CA  . ARG B 2 120 ? 154.627 141.276 188.979 1.00 79.68  ? 140 ARG L CA  1 
ATOM 2950 C C   . ARG B 2 120 ? 153.125 141.208 189.222 1.00 79.68  ? 140 ARG L C   1 
ATOM 2951 O O   . ARG B 2 120 ? 152.442 142.226 189.066 1.00 79.68  ? 140 ARG L O   1 
ATOM 2952 C CB  . ARG B 2 120 ? 154.896 141.844 187.581 1.00 79.68  ? 140 ARG L CB  1 
ATOM 2953 N N   . ALA B 2 121 ? 152.597 140.038 189.591 1.00 78.57  ? 141 ALA L N   1 
ATOM 2954 C CA  . ALA B 2 121 ? 151.164 139.919 189.846 1.00 78.57  ? 141 ALA L CA  1 
ATOM 2955 C C   . ALA B 2 121 ? 150.738 140.780 191.029 1.00 78.57  ? 141 ALA L C   1 
ATOM 2956 O O   . ALA B 2 121 ? 149.685 141.427 190.988 1.00 78.57  ? 141 ALA L O   1 
ATOM 2957 C CB  . ALA B 2 121 ? 150.793 138.456 190.085 1.00 78.57  ? 141 ALA L CB  1 
ATOM 2958 N N   . GLY B 2 122 ? 151.539 140.799 192.089 1.00 82.96  ? 142 GLY L N   1 
ATOM 2959 C CA  . GLY B 2 122 ? 151.227 141.590 193.265 1.00 82.96  ? 142 GLY L CA  1 
ATOM 2960 C C   . GLY B 2 122 ? 151.432 143.078 193.056 1.00 82.96  ? 142 GLY L C   1 
ATOM 2961 O O   . GLY B 2 122 ? 151.964 143.503 192.030 1.00 82.96  ? 142 GLY L O   1 
ATOM 2962 N N   . HIS B 2 126 ? 145.622 142.986 187.158 1.00 67.70  ? 146 HIS L N   1 
ATOM 2963 C CA  . HIS B 2 126 ? 146.318 143.691 186.088 1.00 67.70  ? 146 HIS L CA  1 
ATOM 2964 C C   . HIS B 2 126 ? 147.230 142.744 185.314 1.00 67.70  ? 146 HIS L C   1 
ATOM 2965 O O   . HIS B 2 126 ? 147.283 142.785 184.085 1.00 67.70  ? 146 HIS L O   1 
ATOM 2966 C CB  . HIS B 2 126 ? 147.126 144.861 186.653 1.00 67.70  ? 146 HIS L CB  1 
ATOM 2967 N N   . SER B 2 127 ? 147.946 141.893 186.044 1.00 73.35  ? 147 SER L N   1 
ATOM 2968 C CA  . SER B 2 127 ? 148.848 140.933 185.430 1.00 73.35  ? 147 SER L CA  1 
ATOM 2969 C C   . SER B 2 127 ? 148.070 139.713 184.942 1.00 73.35  ? 147 SER L C   1 
ATOM 2970 O O   . SER B 2 127 ? 146.841 139.647 185.029 1.00 73.35  ? 147 SER L O   1 
ATOM 2971 C CB  . SER B 2 127 ? 149.944 140.529 186.413 1.00 73.35  ? 147 SER L CB  1 
ATOM 2972 O OG  . SER B 2 127 ? 150.516 139.284 186.050 1.00 73.35  ? 147 SER L OG  1 
ATOM 2973 N N   . PHE B 2 128 ? 148.807 138.732 184.415 1.00 67.53  ? 148 PHE L N   1 
ATOM 2974 C CA  . PHE B 2 128 ? 148.234 137.497 183.880 1.00 67.53  ? 148 PHE L CA  1 
ATOM 2975 C C   . PHE B 2 128 ? 147.197 137.774 182.796 1.00 67.53  ? 148 PHE L C   1 
ATOM 2976 O O   . PHE B 2 128 ? 146.233 137.021 182.635 1.00 67.53  ? 148 PHE L O   1 
ATOM 2977 C CB  . PHE B 2 128 ? 147.628 136.635 184.992 1.00 67.53  ? 148 PHE L CB  1 
ATOM 2978 C CG  . PHE B 2 128 ? 148.642 136.091 185.953 1.00 67.53  ? 148 PHE L CG  1 
ATOM 2979 C CD1 . PHE B 2 128 ? 149.775 135.448 185.486 1.00 67.53  ? 148 PHE L CD1 1 
ATOM 2980 C CD2 . PHE B 2 128 ? 148.467 136.225 187.319 1.00 67.53  ? 148 PHE L CD2 1 
ATOM 2981 C CE1 . PHE B 2 128 ? 150.714 134.946 186.363 1.00 67.53  ? 148 PHE L CE1 1 
ATOM 2982 C CE2 . PHE B 2 128 ? 149.403 135.724 188.202 1.00 67.53  ? 148 PHE L CE2 1 
ATOM 2983 C CZ  . PHE B 2 128 ? 150.529 135.084 187.723 1.00 67.53  ? 148 PHE L CZ  1 
ATOM 2984 N N   . TYR B 2 129 ? 147.387 138.855 182.040 1.00 65.85  ? 149 TYR L N   1 
ATOM 2985 C CA  . TYR B 2 129 ? 146.442 139.174 180.978 1.00 65.85  ? 149 TYR L CA  1 
ATOM 2986 C C   . TYR B 2 129 ? 146.577 138.186 179.824 1.00 65.85  ? 149 TYR L C   1 
ATOM 2987 O O   . TYR B 2 129 ? 145.568 137.686 179.312 1.00 65.85  ? 149 TYR L O   1 
ATOM 2988 C CB  . TYR B 2 129 ? 146.658 140.616 180.507 1.00 65.85  ? 149 TYR L CB  1 
ATOM 2989 C CG  . TYR B 2 129 ? 145.679 141.132 179.463 1.00 65.85  ? 149 TYR L CG  1 
ATOM 2990 C CD1 . TYR B 2 129 ? 144.532 140.421 179.130 1.00 65.85  ? 149 TYR L CD1 1 
ATOM 2991 C CD2 . TYR B 2 129 ? 145.906 142.338 178.814 1.00 65.85  ? 149 TYR L CD2 1 
ATOM 2992 C CE1 . TYR B 2 129 ? 143.648 140.888 178.180 1.00 65.85  ? 149 TYR L CE1 1 
ATOM 2993 C CE2 . TYR B 2 129 ? 145.022 142.814 177.861 1.00 65.85  ? 149 TYR L CE2 1 
ATOM 2994 C CZ  . TYR B 2 129 ? 143.897 142.085 177.551 1.00 65.85  ? 149 TYR L CZ  1 
ATOM 2995 O OH  . TYR B 2 129 ? 143.016 142.553 176.606 1.00 65.85  ? 149 TYR L OH  1 
ATOM 2996 N N   . PHE B 2 130 ? 147.818 137.866 179.425 1.00 58.77  ? 150 PHE L N   1 
ATOM 2997 C CA  . PHE B 2 130 ? 148.074 137.024 178.261 1.00 58.77  ? 150 PHE L CA  1 
ATOM 2998 C C   . PHE B 2 130 ? 147.395 137.675 177.064 1.00 58.77  ? 150 PHE L C   1 
ATOM 2999 O O   . PHE B 2 130 ? 146.358 137.179 176.606 1.00 58.77  ? 150 PHE L O   1 
ATOM 3000 C CB  . PHE B 2 130 ? 147.565 135.595 178.470 1.00 58.77  ? 150 PHE L CB  1 
ATOM 3001 C CG  . PHE B 2 130 ? 148.438 134.749 179.358 1.00 58.77  ? 150 PHE L CG  1 
ATOM 3002 C CD1 . PHE B 2 130 ? 148.209 133.389 179.460 1.00 58.77  ? 150 PHE L CD1 1 
ATOM 3003 C CD2 . PHE B 2 130 ? 149.482 135.301 180.081 1.00 58.77  ? 150 PHE L CD2 1 
ATOM 3004 C CE1 . PHE B 2 130 ? 148.995 132.595 180.269 1.00 58.77  ? 150 PHE L CE1 1 
ATOM 3005 C CE2 . PHE B 2 130 ? 150.275 134.512 180.894 1.00 58.77  ? 150 PHE L CE2 1 
ATOM 3006 C CZ  . PHE B 2 130 ? 150.029 133.155 180.985 1.00 58.77  ? 150 PHE L CZ  1 
ATOM 3007 N N   . PRO B 2 131 ? 147.938 138.781 176.549 1.00 53.04  ? 151 PRO L N   1 
ATOM 3008 C CA  . PRO B 2 131 ? 147.145 139.679 175.697 1.00 53.04  ? 151 PRO L CA  1 
ATOM 3009 C C   . PRO B 2 131 ? 146.469 138.948 174.547 1.00 53.04  ? 151 PRO L C   1 
ATOM 3010 O O   . PRO B 2 131 ? 147.052 138.067 173.910 1.00 53.04  ? 151 PRO L O   1 
ATOM 3011 C CB  . PRO B 2 131 ? 148.182 140.684 175.185 1.00 53.04  ? 151 PRO L CB  1 
ATOM 3012 C CG  . PRO B 2 131 ? 149.281 140.644 176.184 1.00 53.04  ? 151 PRO L CG  1 
ATOM 3013 C CD  . PRO B 2 131 ? 149.335 139.227 176.672 1.00 53.04  ? 151 PRO L CD  1 
ATOM 3014 N N   . GLY B 2 132 ? 145.228 139.321 174.295 1.00 55.23  ? 152 GLY L N   1 
ATOM 3015 C CA  . GLY B 2 132 ? 144.406 138.640 173.304 1.00 55.23  ? 152 GLY L CA  1 
ATOM 3016 C C   . GLY B 2 132 ? 143.443 137.666 173.968 1.00 55.23  ? 152 GLY L C   1 
ATOM 3017 O O   . GLY B 2 132 ? 142.490 138.089 174.624 1.00 55.23  ? 152 GLY L O   1 
ATOM 3018 N N   . GLN B 2 133 ? 143.682 136.371 173.759 1.00 56.41  ? 153 GLN L N   1 
ATOM 3019 C CA  . GLN B 2 133 ? 142.870 135.271 174.272 1.00 56.41  ? 153 GLN L CA  1 
ATOM 3020 C C   . GLN B 2 133 ? 141.521 135.188 173.569 1.00 56.41  ? 153 GLN L C   1 
ATOM 3021 O O   . GLN B 2 133 ? 140.807 134.191 173.716 1.00 56.41  ? 153 GLN L O   1 
ATOM 3022 C CB  . GLN B 2 133 ? 142.627 135.396 175.783 1.00 56.41  ? 153 GLN L CB  1 
ATOM 3023 C CG  . GLN B 2 133 ? 143.831 135.248 176.681 1.00 56.41  ? 153 GLN L CG  1 
ATOM 3024 C CD  . GLN B 2 133 ? 143.461 135.410 178.149 1.00 56.41  ? 153 GLN L CD  1 
ATOM 3025 O OE1 . GLN B 2 133 ? 142.312 135.699 178.481 1.00 56.41  ? 153 GLN L OE1 1 
ATOM 3026 N NE2 . GLN B 2 133 ? 144.428 135.201 179.034 1.00 56.41  ? 153 GLN L NE2 1 
ATOM 3027 N N   . PHE B 2 134 ? 141.166 136.214 172.776 1.00 52.85  ? 154 PHE L N   1 
ATOM 3028 C CA  . PHE B 2 134 ? 139.828 136.294 172.185 1.00 52.85  ? 154 PHE L CA  1 
ATOM 3029 C C   . PHE B 2 134 ? 139.984 136.812 170.755 1.00 52.85  ? 154 PHE L C   1 
ATOM 3030 O O   . PHE B 2 134 ? 139.886 138.016 170.506 1.00 52.85  ? 154 PHE L O   1 
ATOM 3031 C CB  . PHE B 2 134 ? 138.911 137.206 172.998 1.00 52.85  ? 154 PHE L CB  1 
ATOM 3032 C CG  . PHE B 2 134 ? 138.949 136.950 174.477 1.00 52.85  ? 154 PHE L CG  1 
ATOM 3033 C CD1 . PHE B 2 134 ? 138.503 135.754 175.010 1.00 52.85  ? 154 PHE L CD1 1 
ATOM 3034 C CD2 . PHE B 2 134 ? 139.415 137.930 175.340 1.00 52.85  ? 154 PHE L CD2 1 
ATOM 3035 C CE1 . PHE B 2 134 ? 138.545 135.532 176.375 1.00 52.85  ? 154 PHE L CE1 1 
ATOM 3036 C CE2 . PHE B 2 134 ? 139.452 137.716 176.704 1.00 52.85  ? 154 PHE L CE2 1 
ATOM 3037 C CZ  . PHE B 2 134 ? 139.017 136.516 177.223 1.00 52.85  ? 154 PHE L CZ  1 
ATOM 3038 N N   . ALA B 2 135 ? 140.196 135.891 169.819 1.00 46.26  ? 155 ALA L N   1 
ATOM 3039 C CA  . ALA B 2 135 ? 140.284 136.199 168.396 1.00 46.26  ? 155 ALA L CA  1 
ATOM 3040 C C   . ALA B 2 135 ? 140.514 134.891 167.653 1.00 46.26  ? 155 ALA L C   1 
ATOM 3041 O O   . ALA B 2 135 ? 140.958 133.895 168.232 1.00 46.26  ? 155 ALA L O   1 
ATOM 3042 C CB  . ALA B 2 135 ? 141.408 137.188 168.072 1.00 46.26  ? 155 ALA L CB  1 
ATOM 3043 N N   . PHE B 2 136 ? 140.206 134.906 166.356 1.00 41.96  ? 156 PHE L N   1 
ATOM 3044 C CA  . PHE B 2 136 ? 140.774 133.897 165.475 1.00 41.96  ? 156 PHE L CA  1 
ATOM 3045 C C   . PHE B 2 136 ? 142.254 134.161 165.249 1.00 41.96  ? 156 PHE L C   1 
ATOM 3046 O O   . PHE B 2 136 ? 143.000 133.241 164.891 1.00 41.96  ? 156 PHE L O   1 
ATOM 3047 C CB  . PHE B 2 136 ? 140.027 133.863 164.141 1.00 41.96  ? 156 PHE L CB  1 
ATOM 3048 C CG  . PHE B 2 136 ? 139.750 135.221 163.560 1.00 41.96  ? 156 PHE L CG  1 
ATOM 3049 C CD1 . PHE B 2 136 ? 140.735 135.918 162.881 1.00 41.96  ? 156 PHE L CD1 1 
ATOM 3050 C CD2 . PHE B 2 136 ? 138.498 135.795 163.683 1.00 41.96  ? 156 PHE L CD2 1 
ATOM 3051 C CE1 . PHE B 2 136 ? 140.477 137.162 162.343 1.00 41.96  ? 156 PHE L CE1 1 
ATOM 3052 C CE2 . PHE B 2 136 ? 138.234 137.039 163.148 1.00 41.96  ? 156 PHE L CE2 1 
ATOM 3053 C CZ  . PHE B 2 136 ? 139.224 137.723 162.478 1.00 41.96  ? 156 PHE L CZ  1 
ATOM 3054 N N   . SER B 2 137 ? 142.681 135.405 165.459 1.00 44.39  ? 157 SER L N   1 
ATOM 3055 C CA  . SER B 2 137 ? 144.077 135.818 165.371 1.00 44.39  ? 157 SER L CA  1 
ATOM 3056 C C   . SER B 2 137 ? 144.681 135.507 164.010 1.00 44.39  ? 157 SER L C   1 
ATOM 3057 O O   . SER B 2 137 ? 143.975 135.225 163.042 1.00 44.39  ? 157 SER L O   1 
ATOM 3058 C CB  . SER B 2 137 ? 144.900 135.155 166.476 1.00 44.39  ? 157 SER L CB  1 
ATOM 3059 O OG  . SER B 2 137 ? 146.274 135.478 166.351 1.00 44.39  ? 157 SER L OG  1 
ATOM 3060 O OXT . SER B 2 137 ? 145.900 135.541 163.857 1.00 44.39  ? 157 SER L OXT 1 
ATOM 3061 N N   . SER C 3 6   ? 164.492 115.373 122.219 1.00 77.51  ? 6   SER A N   1 
ATOM 3062 C CA  . SER C 3 6   ? 163.594 115.947 121.224 1.00 77.51  ? 6   SER A CA  1 
ATOM 3063 C C   . SER C 3 6   ? 163.644 117.471 121.254 1.00 77.51  ? 6   SER A C   1 
ATOM 3064 O O   . SER C 3 6   ? 162.682 118.126 121.656 1.00 77.51  ? 6   SER A O   1 
ATOM 3065 C CB  . SER C 3 6   ? 162.161 115.462 121.453 1.00 77.51  ? 6   SER A CB  1 
ATOM 3066 O OG  . SER C 3 6   ? 161.487 116.283 122.391 1.00 77.51  ? 6   SER A OG  1 
ATOM 3067 N N   . ALA C 3 7   ? 164.778 118.032 120.826 1.00 77.22  ? 7   ALA A N   1 
ATOM 3068 C CA  . ALA C 3 7   ? 164.929 119.482 120.792 1.00 77.22  ? 7   ALA A CA  1 
ATOM 3069 C C   . ALA C 3 7   ? 164.017 120.136 119.763 1.00 77.22  ? 7   ALA A C   1 
ATOM 3070 O O   . ALA C 3 7   ? 163.679 121.316 119.915 1.00 77.22  ? 7   ALA A O   1 
ATOM 3071 C CB  . ALA C 3 7   ? 166.385 119.853 120.506 1.00 77.22  ? 7   ALA A CB  1 
ATOM 3072 N N   . GLU C 3 8   ? 163.617 119.402 118.721 1.00 72.16  ? 8   GLU A N   1 
ATOM 3073 C CA  . GLU C 3 8   ? 162.708 119.963 117.727 1.00 72.16  ? 8   GLU A CA  1 
ATOM 3074 C C   . GLU C 3 8   ? 161.361 120.311 118.346 1.00 72.16  ? 8   GLU A C   1 
ATOM 3075 O O   . GLU C 3 8   ? 160.784 121.362 118.043 1.00 72.16  ? 8   GLU A O   1 
ATOM 3076 C CB  . GLU C 3 8   ? 162.530 118.983 116.567 1.00 72.16  ? 8   GLU A CB  1 
ATOM 3077 N N   . ASP C 3 9   ? 160.845 119.442 119.218 1.00 68.57  ? 9   ASP A N   1 
ATOM 3078 C CA  . ASP C 3 9   ? 159.584 119.731 119.893 1.00 68.57  ? 9   ASP A CA  1 
ATOM 3079 C C   . ASP C 3 9   ? 159.711 120.948 120.801 1.00 68.57  ? 9   ASP A C   1 
ATOM 3080 O O   . ASP C 3 9   ? 158.793 121.773 120.877 1.00 68.57  ? 9   ASP A O   1 
ATOM 3081 C CB  . ASP C 3 9   ? 159.122 118.511 120.689 1.00 68.57  ? 9   ASP A CB  1 
ATOM 3082 C CG  . ASP C 3 9   ? 158.688 117.364 119.797 1.00 68.57  ? 9   ASP A CG  1 
ATOM 3083 O OD1 . ASP C 3 9   ? 158.213 117.630 118.673 1.00 68.57  ? 9   ASP A OD1 1 
ATOM 3084 O OD2 . ASP C 3 9   ? 158.823 116.196 120.220 1.00 68.57  ? 9   ASP A OD2 1 
ATOM 3085 N N   . LYS C 3 10  ? 160.840 121.072 121.504 1.00 61.56  ? 10  LYS A N   1 
ATOM 3086 C CA  . LYS C 3 10  ? 161.056 122.239 122.354 1.00 61.56  ? 10  LYS A CA  1 
ATOM 3087 C C   . LYS C 3 10  ? 161.106 123.519 121.530 1.00 61.56  ? 10  LYS A C   1 
ATOM 3088 O O   . LYS C 3 10  ? 160.517 124.538 121.913 1.00 61.56  ? 10  LYS A O   1 
ATOM 3089 C CB  . LYS C 3 10  ? 162.343 122.067 123.162 1.00 61.56  ? 10  LYS A CB  1 
ATOM 3090 N N   . ALA C 3 11  ? 161.801 123.487 120.391 1.00 58.29  ? 11  ALA A N   1 
ATOM 3091 C CA  . ALA C 3 11  ? 161.843 124.658 119.522 1.00 58.29  ? 11  ALA A CA  1 
ATOM 3092 C C   . ALA C 3 11  ? 160.456 124.999 118.992 1.00 58.29  ? 11  ALA A C   1 
ATOM 3093 O O   . ALA C 3 11  ? 160.075 126.174 118.934 1.00 58.29  ? 11  ALA A O   1 
ATOM 3094 C CB  . ALA C 3 11  ? 162.818 124.423 118.369 1.00 58.29  ? 11  ALA A CB  1 
ATOM 3095 N N   . ALA C 3 12  ? 159.683 123.979 118.608 1.00 53.24  ? 12  ALA A N   1 
ATOM 3096 C CA  . ALA C 3 12  ? 158.339 124.218 118.093 1.00 53.24  ? 12  ALA A CA  1 
ATOM 3097 C C   . ALA C 3 12  ? 157.437 124.836 119.153 1.00 53.24  ? 12  ALA A C   1 
ATOM 3098 O O   . ALA C 3 12  ? 156.689 125.779 118.868 1.00 53.24  ? 12  ALA A O   1 
ATOM 3099 C CB  . ALA C 3 12  ? 157.739 122.914 117.570 1.00 53.24  ? 12  ALA A CB  1 
ATOM 3100 N N   . VAL C 3 13  ? 157.492 124.324 120.386 1.00 49.48  ? 13  VAL A N   1 
ATOM 3101 C CA  . VAL C 3 13  ? 156.627 124.873 121.427 1.00 49.48  ? 13  VAL A CA  1 
ATOM 3102 C C   . VAL C 3 13  ? 157.085 126.269 121.833 1.00 49.48  ? 13  VAL A C   1 
ATOM 3103 O O   . VAL C 3 13  ? 156.255 127.123 122.163 1.00 49.48  ? 13  VAL A O   1 
ATOM 3104 C CB  . VAL C 3 13  ? 156.533 123.923 122.639 1.00 49.48  ? 13  VAL A CB  1 
ATOM 3105 C CG1 . VAL C 3 13  ? 155.974 122.571 122.213 1.00 49.48  ? 13  VAL A CG1 1 
ATOM 3106 C CG2 . VAL C 3 13  ? 157.876 123.762 123.327 1.00 49.48  ? 13  VAL A CG2 1 
ATOM 3107 N N   . GLU C 3 14  ? 158.394 126.540 121.806 1.00 48.91  ? 14  GLU A N   1 
ATOM 3108 C CA  . GLU C 3 14  ? 158.864 127.897 122.073 1.00 48.91  ? 14  GLU A CA  1 
ATOM 3109 C C   . GLU C 3 14  ? 158.383 128.867 121.001 1.00 48.91  ? 14  GLU A C   1 
ATOM 3110 O O   . GLU C 3 14  ? 157.952 129.987 121.309 1.00 48.91  ? 14  GLU A O   1 
ATOM 3111 C CB  . GLU C 3 14  ? 160.390 127.915 122.170 1.00 48.91  ? 14  GLU A CB  1 
ATOM 3112 N N   . ARG C 3 15  ? 158.446 128.453 119.732 1.00 47.74  ? 15  ARG A N   1 
ATOM 3113 C CA  . ARG C 3 15  ? 157.941 129.294 118.652 1.00 47.74  ? 15  ARG A CA  1 
ATOM 3114 C C   . ARG C 3 15  ? 156.442 129.524 118.790 1.00 47.74  ? 15  ARG A C   1 
ATOM 3115 O O   . ARG C 3 15  ? 155.954 130.638 118.567 1.00 47.74  ? 15  ARG A O   1 
ATOM 3116 C CB  . ARG C 3 15  ? 158.271 128.659 117.300 1.00 47.74  ? 15  ARG A CB  1 
ATOM 3117 C CG  . ARG C 3 15  ? 157.511 129.252 116.125 1.00 47.74  ? 15  ARG A CG  1 
ATOM 3118 C CD  . ARG C 3 15  ? 157.169 128.186 115.097 1.00 47.74  ? 15  ARG A CD  1 
ATOM 3119 N NE  . ARG C 3 15  ? 156.152 127.263 115.585 1.00 47.74  ? 15  ARG A NE  1 
ATOM 3120 C CZ  . ARG C 3 15  ? 156.030 126.004 115.189 1.00 47.74  ? 15  ARG A CZ  1 
ATOM 3121 N NH1 . ARG C 3 15  ? 156.850 125.479 114.293 1.00 47.74  ? 15  ARG A NH1 1 
ATOM 3122 N NH2 . ARG C 3 15  ? 155.061 125.252 115.703 1.00 47.74  ? 15  ARG A NH2 1 
ATOM 3123 N N   . SER C 3 16  ? 155.694 128.482 119.161 1.00 43.93  ? 16  SER A N   1 
ATOM 3124 C CA  . SER C 3 16  ? 154.256 128.631 119.356 1.00 43.93  ? 16  SER A CA  1 
ATOM 3125 C C   . SER C 3 16  ? 153.948 129.572 120.515 1.00 43.93  ? 16  SER A C   1 
ATOM 3126 O O   . SER C 3 16  ? 152.997 130.359 120.448 1.00 43.93  ? 16  SER A O   1 
ATOM 3127 C CB  . SER C 3 16  ? 153.615 127.263 119.589 1.00 43.93  ? 16  SER A CB  1 
ATOM 3128 O OG  . SER C 3 16  ? 153.964 126.359 118.556 1.00 43.93  ? 16  SER A OG  1 
ATOM 3129 N N   . LYS C 3 17  ? 154.732 129.495 121.593 1.00 46.07  ? 17  LYS A N   1 
ATOM 3130 C CA  . LYS C 3 17  ? 154.545 130.411 122.714 1.00 46.07  ? 17  LYS A CA  1 
ATOM 3131 C C   . LYS C 3 17  ? 154.824 131.850 122.300 1.00 46.07  ? 17  LYS A C   1 
ATOM 3132 O O   . LYS C 3 17  ? 154.082 132.767 122.671 1.00 46.07  ? 17  LYS A O   1 
ATOM 3133 C CB  . LYS C 3 17  ? 155.443 130.002 123.881 1.00 46.07  ? 17  LYS A CB  1 
ATOM 3134 C CG  . LYS C 3 17  ? 154.811 128.994 124.828 1.00 46.07  ? 17  LYS A CG  1 
ATOM 3135 C CD  . LYS C 3 17  ? 155.866 128.170 125.552 1.00 46.07  ? 17  LYS A CD  1 
ATOM 3136 C CE  . LYS C 3 17  ? 157.025 129.034 126.026 1.00 46.07  ? 17  LYS A CE  1 
ATOM 3137 N NZ  . LYS C 3 17  ? 156.608 129.992 127.086 1.00 46.07  ? 17  LYS A NZ  1 
ATOM 3138 N N   . MET C 3 18  ? 155.891 132.070 121.529 1.00 44.97  ? 18  MET A N   1 
ATOM 3139 C CA  . MET C 3 18  ? 156.161 133.415 121.029 1.00 44.97  ? 18  MET A CA  1 
ATOM 3140 C C   . MET C 3 18  ? 155.021 133.907 120.145 1.00 44.97  ? 18  MET A C   1 
ATOM 3141 O O   . MET C 3 18  ? 154.596 135.067 120.246 1.00 44.97  ? 18  MET A O   1 
ATOM 3142 C CB  . MET C 3 18  ? 157.484 133.437 120.266 1.00 44.97  ? 18  MET A CB  1 
ATOM 3143 N N   . ILE C 3 19  ? 154.499 133.029 119.285 1.00 41.40  ? 19  ILE A N   1 
ATOM 3144 C CA  . ILE C 3 19  ? 153.420 133.408 118.379 1.00 41.40  ? 19  ILE A CA  1 
ATOM 3145 C C   . ILE C 3 19  ? 152.163 133.772 119.159 1.00 41.40  ? 19  ILE A C   1 
ATOM 3146 O O   . ILE C 3 19  ? 151.498 134.769 118.857 1.00 41.40  ? 19  ILE A O   1 
ATOM 3147 C CB  . ILE C 3 19  ? 153.154 132.278 117.366 1.00 41.40  ? 19  ILE A CB  1 
ATOM 3148 C CG1 . ILE C 3 19  ? 154.246 132.255 116.295 1.00 41.40  ? 19  ILE A CG1 1 
ATOM 3149 C CG2 . ILE C 3 19  ? 151.787 132.440 116.720 1.00 41.40  ? 19  ILE A CG2 1 
ATOM 3150 C CD1 . ILE C 3 19  ? 154.224 131.016 115.430 1.00 41.40  ? 19  ILE A CD1 1 
ATOM 3151 N N   . ASP C 3 20  ? 151.817 132.979 120.178 1.00 42.44  ? 20  ASP A N   1 
ATOM 3152 C CA  . ASP C 3 20  ? 150.595 133.265 120.924 1.00 42.44  ? 20  ASP A CA  1 
ATOM 3153 C C   . ASP C 3 20  ? 150.752 134.502 121.801 1.00 42.44  ? 20  ASP A C   1 
ATOM 3154 O O   . ASP C 3 20  ? 149.785 135.247 121.992 1.00 42.44  ? 20  ASP A O   1 
ATOM 3155 C CB  . ASP C 3 20  ? 150.145 132.025 121.721 1.00 42.44  ? 20  ASP A CB  1 
ATOM 3156 C CG  . ASP C 3 20  ? 150.928 131.787 123.021 1.00 42.44  ? 20  ASP A CG  1 
ATOM 3157 O OD1 . ASP C 3 20  ? 151.638 132.673 123.533 1.00 42.44  ? 20  ASP A OD1 1 
ATOM 3158 O OD2 . ASP C 3 20  ? 150.821 130.659 123.546 1.00 42.44  ? 20  ASP A OD2 1 
ATOM 3159 N N   . ARG C 3 21  ? 151.956 134.748 122.327 1.00 45.56  ? 21  ARG A N   1 
ATOM 3160 C CA  . ARG C 3 21  ? 152.201 135.993 123.048 1.00 45.56  ? 21  ARG A CA  1 
ATOM 3161 C C   . ARG C 3 21  ? 152.042 137.198 122.128 1.00 45.56  ? 21  ARG A C   1 
ATOM 3162 O O   . ARG C 3 21  ? 151.419 138.201 122.505 1.00 45.56  ? 21  ARG A O   1 
ATOM 3163 C CB  . ARG C 3 21  ? 153.596 135.972 123.671 1.00 45.56  ? 21  ARG A CB  1 
ATOM 3164 C CG  . ARG C 3 21  ? 153.918 137.190 124.521 1.00 45.56  ? 21  ARG A CG  1 
ATOM 3165 C CD  . ARG C 3 21  ? 155.201 136.992 125.312 1.00 45.56  ? 21  ARG A CD  1 
ATOM 3166 N NE  . ARG C 3 21  ? 155.418 135.595 125.670 1.00 45.56  ? 21  ARG A NE  1 
ATOM 3167 C CZ  . ARG C 3 21  ? 156.459 134.873 125.277 1.00 45.56  ? 21  ARG A CZ  1 
ATOM 3168 N NH1 . ARG C 3 21  ? 157.404 135.386 124.507 1.00 45.56  ? 21  ARG A NH1 1 
ATOM 3169 N NH2 . ARG C 3 21  ? 156.553 133.605 125.666 1.00 45.56  ? 21  ARG A NH2 1 
ATOM 3170 N N   . ASN C 3 22  ? 152.593 137.116 120.913 1.00 46.08  ? 22  ASN A N   1 
ATOM 3171 C CA  . ASN C 3 22  ? 152.432 138.206 119.956 1.00 46.08  ? 22  ASN A CA  1 
ATOM 3172 C C   . ASN C 3 22  ? 150.968 138.396 119.579 1.00 46.08  ? 22  ASN A C   1 
ATOM 3173 O O   . ASN C 3 22  ? 150.496 139.531 119.440 1.00 46.08  ? 22  ASN A O   1 
ATOM 3174 C CB  . ASN C 3 22  ? 153.278 137.941 118.711 1.00 46.08  ? 22  ASN A CB  1 
ATOM 3175 C CG  . ASN C 3 22  ? 154.757 138.163 118.954 1.00 46.08  ? 22  ASN A CG  1 
ATOM 3176 O OD1 . ASN C 3 22  ? 155.147 139.030 119.736 1.00 46.08  ? 22  ASN A OD1 1 
ATOM 3177 N ND2 . ASN C 3 22  ? 155.591 137.377 118.283 1.00 46.08  ? 22  ASN A ND2 1 
ATOM 3178 N N   . LEU C 3 23  ? 150.235 137.294 119.405 1.00 42.54  ? 23  LEU A N   1 
ATOM 3179 C CA  . LEU C 3 23  ? 148.815 137.382 119.079 1.00 42.54  ? 23  LEU A CA  1 
ATOM 3180 C C   . LEU C 3 23  ? 148.029 138.045 120.202 1.00 42.54  ? 23  LEU A C   1 
ATOM 3181 O O   . LEU C 3 23  ? 147.158 138.885 119.949 1.00 42.54  ? 23  LEU A O   1 
ATOM 3182 C CB  . LEU C 3 23  ? 148.260 135.988 118.790 1.00 42.54  ? 23  LEU A CB  1 
ATOM 3183 C CG  . LEU C 3 23  ? 148.506 135.420 117.393 1.00 42.54  ? 23  LEU A CG  1 
ATOM 3184 C CD1 . LEU C 3 23  ? 147.961 134.006 117.297 1.00 42.54  ? 23  LEU A CD1 1 
ATOM 3185 C CD2 . LEU C 3 23  ? 147.880 136.311 116.334 1.00 42.54  ? 23  LEU A CD2 1 
ATOM 3186 N N   . ARG C 3 24  ? 148.319 137.674 121.452 1.00 44.31  ? 24  ARG A N   1 
ATOM 3187 C CA  . ARG C 3 24  ? 147.641 138.292 122.586 1.00 44.31  ? 24  ARG A CA  1 
ATOM 3188 C C   . ARG C 3 24  ? 147.959 139.778 122.673 1.00 44.31  ? 24  ARG A C   1 
ATOM 3189 O O   . ARG C 3 24  ? 147.070 140.595 122.942 1.00 44.31  ? 24  ARG A O   1 
ATOM 3190 C CB  . ARG C 3 24  ? 148.031 137.582 123.882 1.00 44.31  ? 24  ARG A CB  1 
ATOM 3191 C CG  . ARG C 3 24  ? 147.376 136.223 124.068 1.00 44.31  ? 24  ARG A CG  1 
ATOM 3192 C CD  . ARG C 3 24  ? 147.782 135.591 125.390 1.00 44.31  ? 24  ARG A CD  1 
ATOM 3193 N NE  . ARG C 3 24  ? 148.986 134.778 125.260 1.00 44.31  ? 24  ARG A NE  1 
ATOM 3194 C CZ  . ARG C 3 24  ? 150.051 134.886 126.042 1.00 44.31  ? 24  ARG A CZ  1 
ATOM 3195 N NH1 . ARG C 3 24  ? 150.098 135.768 127.027 1.00 44.31  ? 24  ARG A NH1 1 
ATOM 3196 N NH2 . ARG C 3 24  ? 151.095 134.090 125.831 1.00 44.31  ? 24  ARG A NH2 1 
ATOM 3197 N N   . GLU C 3 25  ? 149.223 140.149 122.449 1.00 45.51  ? 25  GLU A N   1 
ATOM 3198 C CA  . GLU C 3 25  ? 149.590 141.562 122.474 1.00 45.51  ? 25  GLU A CA  1 
ATOM 3199 C C   . GLU C 3 25  ? 148.872 142.338 121.376 1.00 45.51  ? 25  GLU A C   1 
ATOM 3200 O O   . GLU C 3 25  ? 148.366 143.442 121.614 1.00 45.51  ? 25  GLU A O   1 
ATOM 3201 C CB  . GLU C 3 25  ? 151.105 141.713 122.338 1.00 45.51  ? 25  GLU A CB  1 
ATOM 3202 N N   . ASP C 3 26  ? 148.812 141.772 120.168 1.00 45.58  ? 26  ASP A N   1 
ATOM 3203 C CA  . ASP C 3 26  ? 148.129 142.443 119.066 1.00 45.58  ? 26  ASP A CA  1 
ATOM 3204 C C   . ASP C 3 26  ? 146.638 142.587 119.346 1.00 45.58  ? 26  ASP A C   1 
ATOM 3205 O O   . ASP C 3 26  ? 146.045 143.634 119.063 1.00 45.58  ? 26  ASP A O   1 
ATOM 3206 C CB  . ASP C 3 26  ? 148.360 141.679 117.762 1.00 45.58  ? 26  ASP A CB  1 
ATOM 3207 N N   . GLY C 3 27  ? 146.015 141.545 119.900 1.00 45.96  ? 27  GLY A N   1 
ATOM 3208 C CA  . GLY C 3 27  ? 144.604 141.633 120.235 1.00 45.96  ? 27  GLY A CA  1 
ATOM 3209 C C   . GLY C 3 27  ? 144.324 142.661 121.313 1.00 45.96  ? 27  GLY A C   1 
ATOM 3210 O O   . GLY C 3 27  ? 143.342 143.403 121.238 1.00 45.96  ? 27  GLY A O   1 
ATOM 3211 N N   . GLU C 3 28  ? 145.184 142.718 122.334 1.00 45.98  ? 28  GLU A N   1 
ATOM 3212 C CA  . GLU C 3 28  ? 145.025 143.725 123.378 1.00 45.98  ? 28  GLU A CA  1 
ATOM 3213 C C   . GLU C 3 28  ? 145.183 145.130 122.813 1.00 45.98  ? 28  GLU A C   1 
ATOM 3214 O O   . GLU C 3 28  ? 144.436 146.043 123.184 1.00 45.98  ? 28  GLU A O   1 
ATOM 3215 C CB  . GLU C 3 28  ? 146.032 143.480 124.501 1.00 45.98  ? 28  GLU A CB  1 
ATOM 3216 N N   . LYS C 3 29  ? 146.154 145.325 121.917 1.00 46.46  ? 29  LYS A N   1 
ATOM 3217 C CA  . LYS C 3 29  ? 146.340 146.638 121.305 1.00 46.46  ? 29  LYS A CA  1 
ATOM 3218 C C   . LYS C 3 29  ? 145.145 147.024 120.441 1.00 46.46  ? 29  LYS A C   1 
ATOM 3219 O O   . LYS C 3 29  ? 144.706 148.180 120.456 1.00 46.46  ? 29  LYS A O   1 
ATOM 3220 C CB  . LYS C 3 29  ? 147.626 146.653 120.479 1.00 46.46  ? 29  LYS A CB  1 
ATOM 3221 N N   . ALA C 3 30  ? 144.604 146.068 119.681 1.00 46.24  ? 30  ALA A N   1 
ATOM 3222 C CA  . ALA C 3 30  ? 143.498 146.375 118.780 1.00 46.24  ? 30  ALA A CA  1 
ATOM 3223 C C   . ALA C 3 30  ? 142.192 146.598 119.532 1.00 46.24  ? 30  ALA A C   1 
ATOM 3224 O O   . ALA C 3 30  ? 141.351 147.386 119.085 1.00 46.24  ? 30  ALA A O   1 
ATOM 3225 C CB  . ALA C 3 30  ? 143.332 145.256 117.752 1.00 46.24  ? 30  ALA A CB  1 
ATOM 3226 N N   . ALA C 3 31  ? 141.999 145.914 120.663 1.00 49.92  ? 31  ALA A N   1 
ATOM 3227 C CA  . ALA C 3 31  ? 140.741 146.032 121.393 1.00 49.92  ? 31  ALA A CA  1 
ATOM 3228 C C   . ALA C 3 31  ? 140.546 147.424 121.980 1.00 49.92  ? 31  ALA A C   1 
ATOM 3229 O O   . ALA C 3 31  ? 139.405 147.847 122.198 1.00 49.92  ? 31  ALA A O   1 
ATOM 3230 C CB  . ALA C 3 31  ? 140.674 144.977 122.496 1.00 49.92  ? 31  ALA A CB  1 
ATOM 3231 N N   . ARG C 3 32  ? 141.636 148.148 122.244 1.00 50.90  ? 32  ARG A N   1 
ATOM 3232 C CA  . ARG C 3 32  ? 141.523 149.467 122.855 1.00 50.90  ? 32  ARG A CA  1 
ATOM 3233 C C   . ARG C 3 32  ? 140.982 150.517 121.893 1.00 50.90  ? 32  ARG A C   1 
ATOM 3234 O O   . ARG C 3 32  ? 140.457 151.540 122.345 1.00 50.90  ? 32  ARG A O   1 
ATOM 3235 C CB  . ARG C 3 32  ? 142.882 149.917 123.394 1.00 50.90  ? 32  ARG A CB  1 
ATOM 3236 C CG  . ARG C 3 32  ? 143.562 148.906 124.304 1.00 50.90  ? 32  ARG A CG  1 
ATOM 3237 C CD  . ARG C 3 32  ? 142.669 148.505 125.468 1.00 50.90  ? 32  ARG A CD  1 
ATOM 3238 N NE  . ARG C 3 32  ? 142.111 147.169 125.297 1.00 50.90  ? 32  ARG A NE  1 
ATOM 3239 C CZ  . ARG C 3 32  ? 141.218 146.621 126.111 1.00 50.90  ? 32  ARG A CZ  1 
ATOM 3240 N NH1 . ARG C 3 32  ? 140.757 147.269 127.168 1.00 50.90  ? 32  ARG A NH1 1 
ATOM 3241 N NH2 . ARG C 3 32  ? 140.779 145.392 125.858 1.00 50.90  ? 32  ARG A NH2 1 
ATOM 3242 N N   . GLU C 3 33  ? 141.093 150.292 120.588 1.00 51.63  ? 33  GLU A N   1 
ATOM 3243 C CA  . GLU C 3 33  ? 140.646 151.259 119.599 1.00 51.63  ? 33  GLU A CA  1 
ATOM 3244 C C   . GLU C 3 33  ? 139.134 151.179 119.408 1.00 51.63  ? 33  GLU A C   1 
ATOM 3245 O O   . GLU C 3 33  ? 138.484 150.200 119.780 1.00 51.63  ? 33  GLU A O   1 
ATOM 3246 C CB  . GLU C 3 33  ? 141.355 151.030 118.263 1.00 51.63  ? 33  GLU A CB  1 
ATOM 3247 N N   . VAL C 3 34  ? 138.579 152.234 118.815 1.00 54.04  ? 34  VAL A N   1 
ATOM 3248 C CA  . VAL C 3 34  ? 137.149 152.331 118.545 1.00 54.04  ? 34  VAL A CA  1 
ATOM 3249 C C   . VAL C 3 34  ? 136.947 152.407 117.037 1.00 54.04  ? 34  VAL A C   1 
ATOM 3250 O O   . VAL C 3 34  ? 137.691 153.101 116.336 1.00 54.04  ? 34  VAL A O   1 
ATOM 3251 C CB  . VAL C 3 34  ? 136.515 153.541 119.266 1.00 54.04  ? 34  VAL A CB  1 
ATOM 3252 C CG1 . VAL C 3 34  ? 137.216 154.832 118.884 1.00 54.04  ? 34  VAL A CG1 1 
ATOM 3253 C CG2 . VAL C 3 34  ? 135.029 153.630 118.963 1.00 54.04  ? 34  VAL A CG2 1 
ATOM 3254 N N   . LYS C 3 35  ? 135.954 151.673 116.539 1.00 52.75  ? 35  LYS A N   1 
ATOM 3255 C CA  . LYS C 3 35  ? 135.714 151.533 115.110 1.00 52.75  ? 35  LYS A CA  1 
ATOM 3256 C C   . LYS C 3 35  ? 134.321 152.034 114.751 1.00 52.75  ? 35  LYS A C   1 
ATOM 3257 O O   . LYS C 3 35  ? 133.352 151.774 115.470 1.00 52.75  ? 35  LYS A O   1 
ATOM 3258 C CB  . LYS C 3 35  ? 135.870 150.075 114.669 1.00 52.75  ? 35  LYS A CB  1 
ATOM 3259 N N   . LEU C 3 36  ? 134.232 152.746 113.632 1.00 47.65  ? 36  LEU A N   1 
ATOM 3260 C CA  . LEU C 3 36  ? 132.986 153.286 113.109 1.00 47.65  ? 36  LEU A CA  1 
ATOM 3261 C C   . LEU C 3 36  ? 132.845 152.909 111.640 1.00 47.65  ? 36  LEU A C   1 
ATOM 3262 O O   . LEU C 3 36  ? 133.832 152.695 110.931 1.00 47.65  ? 36  LEU A O   1 
ATOM 3263 C CB  . LEU C 3 36  ? 132.932 154.811 113.270 1.00 47.65  ? 36  LEU A CB  1 
ATOM 3264 C CG  . LEU C 3 36  ? 133.281 155.381 114.644 1.00 47.65  ? 36  LEU A CG  1 
ATOM 3265 C CD1 . LEU C 3 36  ? 133.298 156.898 114.596 1.00 47.65  ? 36  LEU A CD1 1 
ATOM 3266 C CD2 . LEU C 3 36  ? 132.303 154.886 115.695 1.00 47.65  ? 36  LEU A CD2 1 
ATOM 3267 N N   . LEU C 3 37  ? 131.597 152.830 111.180 1.00 46.49  ? 37  LEU A N   1 
ATOM 3268 C CA  . LEU C 3 37  ? 131.315 152.460 109.794 1.00 46.49  ? 37  LEU A CA  1 
ATOM 3269 C C   . LEU C 3 37  ? 130.505 153.566 109.135 1.00 46.49  ? 37  LEU A C   1 
ATOM 3270 O O   . LEU C 3 37  ? 129.439 153.930 109.635 1.00 46.49  ? 37  LEU A O   1 
ATOM 3271 C CB  . LEU C 3 37  ? 130.562 151.128 109.722 1.00 46.49  ? 37  LEU A CB  1 
ATOM 3272 C CG  . LEU C 3 37  ? 129.801 150.835 108.428 1.00 46.49  ? 37  LEU A CG  1 
ATOM 3273 C CD1 . LEU C 3 37  ? 130.763 150.639 107.266 1.00 46.49  ? 37  LEU A CD1 1 
ATOM 3274 C CD2 . LEU C 3 37  ? 128.904 149.619 108.596 1.00 46.49  ? 37  LEU A CD2 1 
ATOM 3275 N N   . LEU C 3 38  ? 130.996 154.085 108.011 1.00 51.14  ? 38  LEU A N   1 
ATOM 3276 C CA  . LEU C 3 38  ? 130.299 155.128 107.267 1.00 51.14  ? 38  LEU A CA  1 
ATOM 3277 C C   . LEU C 3 38  ? 129.391 154.474 106.232 1.00 51.14  ? 38  LEU A C   1 
ATOM 3278 O O   . LEU C 3 38  ? 129.868 153.751 105.352 1.00 51.14  ? 38  LEU A O   1 
ATOM 3279 C CB  . LEU C 3 38  ? 131.296 156.067 106.590 1.00 51.14  ? 38  LEU A CB  1 
ATOM 3280 C CG  . LEU C 3 38  ? 132.413 156.654 107.455 1.00 51.14  ? 38  LEU A CG  1 
ATOM 3281 C CD1 . LEU C 3 38  ? 133.137 157.757 106.704 1.00 51.14  ? 38  LEU A CD1 1 
ATOM 3282 C CD2 . LEU C 3 38  ? 131.869 157.176 108.774 1.00 51.14  ? 38  LEU A CD2 1 
ATOM 3283 N N   . LEU C 3 39  ? 128.089 154.728 106.335 1.00 50.51  ? 39  LEU A N   1 
ATOM 3284 C CA  . LEU C 3 39  ? 127.095 154.052 105.504 1.00 50.51  ? 39  LEU A CA  1 
ATOM 3285 C C   . LEU C 3 39  ? 126.087 155.058 104.952 1.00 50.51  ? 39  LEU A C   1 
ATOM 3286 O O   . LEU C 3 39  ? 124.873 154.885 105.060 1.00 50.51  ? 39  LEU A O   1 
ATOM 3287 C CB  . LEU C 3 39  ? 126.409 152.938 106.294 1.00 50.51  ? 39  LEU A CB  1 
ATOM 3288 C CG  . LEU C 3 39  ? 125.753 151.817 105.487 1.00 50.51  ? 39  LEU A CG  1 
ATOM 3289 C CD1 . LEU C 3 39  ? 126.695 151.317 104.407 1.00 50.51  ? 39  LEU A CD1 1 
ATOM 3290 C CD2 . LEU C 3 39  ? 125.359 150.675 106.405 1.00 50.51  ? 39  LEU A CD2 1 
ATOM 3291 N N   . GLY C 3 40  ? 126.592 156.137 104.358 1.00 57.98  ? 40  GLY A N   1 
ATOM 3292 C CA  . GLY C 3 40  ? 125.732 157.160 103.798 1.00 57.98  ? 40  GLY A CA  1 
ATOM 3293 C C   . GLY C 3 40  ? 124.908 156.666 102.620 1.00 57.98  ? 40  GLY A C   1 
ATOM 3294 O O   . GLY C 3 40  ? 125.126 155.588 102.066 1.00 57.98  ? 40  GLY A O   1 
ATOM 3295 N N   . ALA C 3 41  ? 123.930 157.490 102.236 1.00 64.81  ? 41  ALA A N   1 
ATOM 3296 C CA  . ALA C 3 41  ? 122.923 157.101 101.252 1.00 64.81  ? 41  ALA A CA  1 
ATOM 3297 C C   . ALA C 3 41  ? 123.512 156.797 99.879  1.00 64.81  ? 41  ALA A C   1 
ATOM 3298 O O   . ALA C 3 41  ? 123.491 155.646 99.432  1.00 64.81  ? 41  ALA A O   1 
ATOM 3299 C CB  . ALA C 3 41  ? 121.862 158.196 101.127 1.00 64.81  ? 41  ALA A CB  1 
ATOM 3300 N N   . GLY C 3 42  ? 124.035 157.816 99.200  1.00 80.49  ? 42  GLY A N   1 
ATOM 3301 C CA  . GLY C 3 42  ? 124.669 157.611 97.911  1.00 80.49  ? 42  GLY A CA  1 
ATOM 3302 C C   . GLY C 3 42  ? 124.964 158.901 97.173  1.00 80.49  ? 42  GLY A C   1 
ATOM 3303 O O   . GLY C 3 42  ? 124.112 159.792 97.104  1.00 80.49  ? 42  GLY A O   1 
ATOM 3304 N N   . GLU C 3 43  ? 126.185 159.012 96.641  1.00 90.78  ? 43  GLU A N   1 
ATOM 3305 C CA  . GLU C 3 43  ? 126.655 160.155 95.858  1.00 90.78  ? 43  GLU A CA  1 
ATOM 3306 C C   . GLU C 3 43  ? 126.734 161.423 96.703  1.00 90.78  ? 43  GLU A C   1 
ATOM 3307 O O   . GLU C 3 43  ? 127.278 162.441 96.262  1.00 90.78  ? 43  GLU A O   1 
ATOM 3308 C CB  . GLU C 3 43  ? 125.759 160.383 94.637  1.00 90.78  ? 43  GLU A CB  1 
ATOM 3309 N N   . SER C 3 44  ? 126.194 161.363 97.919  1.00 88.21  ? 44  SER A N   1 
ATOM 3310 C CA  . SER C 3 44  ? 126.391 162.423 98.901  1.00 88.21  ? 44  SER A CA  1 
ATOM 3311 C C   . SER C 3 44  ? 126.546 161.846 100.302 1.00 88.21  ? 44  SER A C   1 
ATOM 3312 O O   . SER C 3 44  ? 126.588 162.617 101.269 1.00 88.21  ? 44  SER A O   1 
ATOM 3313 C CB  . SER C 3 44  ? 125.229 163.423 98.862  1.00 88.21  ? 44  SER A CB  1 
ATOM 3314 O OG  . SER C 3 44  ? 125.031 163.924 97.552  1.00 88.21  ? 44  SER A OG  1 
ATOM 3315 N N   . GLY C 3 45  ? 126.625 160.525 100.441 1.00 82.49  ? 45  GLY A N   1 
ATOM 3316 C CA  . GLY C 3 45  ? 126.666 159.857 101.724 1.00 82.49  ? 45  GLY A CA  1 
ATOM 3317 C C   . GLY C 3 45  ? 128.050 159.364 102.084 1.00 82.49  ? 45  GLY A C   1 
ATOM 3318 O O   . GLY C 3 45  ? 128.859 160.127 102.618 1.00 82.49  ? 45  GLY A O   1 
ATOM 3319 N N   . LYS C 3 46  ? 128.316 158.082 101.807 1.00 83.45  ? 46  LYS A N   1 
ATOM 3320 C CA  . LYS C 3 46  ? 129.572 157.402 102.122 1.00 83.45  ? 46  LYS A CA  1 
ATOM 3321 C C   . LYS C 3 46  ? 130.794 158.290 101.919 1.00 83.45  ? 46  LYS A C   1 
ATOM 3322 O O   . LYS C 3 46  ? 131.713 158.288 102.744 1.00 83.45  ? 46  LYS A O   1 
ATOM 3323 C CB  . LYS C 3 46  ? 129.705 156.134 101.277 1.00 83.45  ? 46  LYS A CB  1 
ATOM 3324 N N   . CYS C 3 47  ? 130.824 159.042 100.820 1.00 89.96  ? 47  CYS A N   1 
ATOM 3325 C CA  . CYS C 3 47  ? 131.839 160.077 100.627 1.00 89.96  ? 47  CYS A CA  1 
ATOM 3326 C C   . CYS C 3 47  ? 131.461 161.265 101.508 1.00 89.96  ? 47  CYS A C   1 
ATOM 3327 O O   . CYS C 3 47  ? 130.969 162.298 101.048 1.00 89.96  ? 47  CYS A O   1 
ATOM 3328 C CB  . CYS C 3 47  ? 131.941 160.466 99.157  1.00 89.96  ? 47  CYS A CB  1 
ATOM 3329 S SG  . CYS C 3 47  ? 130.347 160.729 98.332  1.00 89.96  ? 47  CYS A SG  1 
ATOM 3330 N N   . THR C 3 48  ? 131.695 161.106 102.809 1.00 94.83  ? 48  THR A N   1 
ATOM 3331 C CA  . THR C 3 48  ? 131.240 162.063 103.811 1.00 94.83  ? 48  THR A CA  1 
ATOM 3332 C C   . THR C 3 48  ? 132.098 163.329 103.778 1.00 94.83  ? 48  THR A C   1 
ATOM 3333 O O   . THR C 3 48  ? 133.025 163.470 102.975 1.00 94.83  ? 48  THR A O   1 
ATOM 3334 C CB  . THR C 3 48  ? 131.252 161.422 105.199 1.00 94.83  ? 48  THR A CB  1 
ATOM 3335 O OG1 . THR C 3 48  ? 132.602 161.313 105.668 1.00 94.83  ? 48  THR A OG1 1 
ATOM 3336 C CG2 . THR C 3 48  ? 130.624 160.038 105.169 1.00 94.83  ? 48  THR A CG2 1 
ATOM 3337 N N   . ILE C 3 49  ? 131.777 164.275 104.663 1.00 102.60 ? 49  ILE A N   1 
ATOM 3338 C CA  . ILE C 3 49  ? 132.593 165.468 104.853 1.00 102.60 ? 49  ILE A CA  1 
ATOM 3339 C C   . ILE C 3 49  ? 133.532 165.336 106.048 1.00 102.60 ? 49  ILE A C   1 
ATOM 3340 O O   . ILE C 3 49  ? 134.480 166.129 106.166 1.00 102.60 ? 49  ILE A O   1 
ATOM 3341 C CB  . ILE C 3 49  ? 131.709 166.722 105.011 1.00 102.60 ? 49  ILE A CB  1 
ATOM 3342 N N   . VAL C 3 50  ? 133.305 164.358 106.928 1.00 98.69  ? 50  VAL A N   1 
ATOM 3343 C CA  . VAL C 3 50  ? 134.161 164.188 108.094 1.00 98.69  ? 50  VAL A CA  1 
ATOM 3344 C C   . VAL C 3 50  ? 135.531 163.641 107.706 1.00 98.69  ? 50  VAL A C   1 
ATOM 3345 O O   . VAL C 3 50  ? 136.463 163.676 108.519 1.00 98.69  ? 50  VAL A O   1 
ATOM 3346 C CB  . VAL C 3 50  ? 133.459 163.283 109.127 1.00 98.69  ? 50  VAL A CB  1 
ATOM 3347 C CG1 . VAL C 3 50  ? 133.498 161.827 108.688 1.00 98.69  ? 50  VAL A CG1 1 
ATOM 3348 C CG2 . VAL C 3 50  ? 134.067 163.457 110.511 1.00 98.69  ? 50  VAL A CG2 1 
ATOM 3349 N N   . LYS C 3 51  ? 135.681 163.133 106.479 1.00 96.41  ? 51  LYS A N   1 
ATOM 3350 C CA  . LYS C 3 51  ? 136.989 162.663 106.028 1.00 96.41  ? 51  LYS A CA  1 
ATOM 3351 C C   . LYS C 3 51  ? 137.991 163.807 105.931 1.00 96.41  ? 51  LYS A C   1 
ATOM 3352 O O   . LYS C 3 51  ? 139.166 163.646 106.284 1.00 96.41  ? 51  LYS A O   1 
ATOM 3353 C CB  . LYS C 3 51  ? 136.862 161.961 104.677 1.00 96.41  ? 51  LYS A CB  1 
ATOM 3354 C CG  . LYS C 3 51  ? 135.627 161.089 104.541 1.00 96.41  ? 51  LYS A CG  1 
ATOM 3355 C CD  . LYS C 3 51  ? 135.830 159.734 105.193 1.00 96.41  ? 51  LYS A CD  1 
ATOM 3356 C CE  . LYS C 3 51  ? 136.999 158.991 104.559 1.00 96.41  ? 51  LYS A CE  1 
ATOM 3357 N NZ  . LYS C 3 51  ? 137.183 157.626 105.128 1.00 96.41  ? 51  LYS A NZ  1 
ATOM 3358 N N   . GLN C 3 52  ? 137.546 164.968 105.455 1.00 106.90 ? 52  GLN A N   1 
ATOM 3359 C CA  . GLN C 3 52  ? 138.442 166.062 105.082 1.00 106.90 ? 52  GLN A CA  1 
ATOM 3360 C C   . GLN C 3 52  ? 138.713 166.992 106.266 1.00 106.90 ? 52  GLN A C   1 
ATOM 3361 O O   . GLN C 3 52  ? 138.153 168.082 106.385 1.00 106.90 ? 52  GLN A O   1 
ATOM 3362 C CB  . GLN C 3 52  ? 137.861 166.828 103.900 1.00 106.90 ? 52  GLN A CB  1 
ATOM 3363 C CG  . GLN C 3 52  ? 137.439 165.937 102.734 1.00 106.90 ? 52  GLN A CG  1 
ATOM 3364 C CD  . GLN C 3 52  ? 135.981 165.515 102.820 1.00 106.90 ? 52  GLN A CD  1 
ATOM 3365 O OE1 . GLN C 3 52  ? 135.576 164.845 103.769 1.00 106.90 ? 52  GLN A OE1 1 
ATOM 3366 N NE2 . GLN C 3 52  ? 135.189 165.891 101.819 1.00 106.90 ? 52  GLN A NE2 1 
ATOM 3367 N N   . MET C 3 53  ? 139.587 166.533 107.158 1.00 110.24 ? 53  MET A N   1 
ATOM 3368 C CA  . MET C 3 53  ? 140.145 167.405 108.192 1.00 110.24 ? 53  MET A CA  1 
ATOM 3369 C C   . MET C 3 53  ? 141.634 167.138 108.367 1.00 110.24 ? 53  MET A C   1 
ATOM 3370 O O   . MET C 3 53  ? 142.258 167.673 109.281 1.00 110.24 ? 53  MET A O   1 
ATOM 3371 C CB  . MET C 3 53  ? 139.425 167.223 109.528 1.00 110.24 ? 53  MET A CB  1 
ATOM 3372 C CG  . MET C 3 53  ? 139.575 165.856 110.158 1.00 110.24 ? 53  MET A CG  1 
ATOM 3373 S SD  . MET C 3 53  ? 138.601 165.723 111.675 1.00 110.24 ? 53  MET A SD  1 
ATOM 3374 C CE  . MET C 3 53  ? 136.946 165.627 110.995 1.00 110.24 ? 53  MET A CE  1 
ATOM 3375 N N   . THR C 3 182 ? 139.482 151.848 96.128  1.00 57.67  ? 182 THR A N   1 
ATOM 3376 C CA  . THR C 3 182 ? 139.373 150.410 95.912  1.00 57.67  ? 182 THR A CA  1 
ATOM 3377 C C   . THR C 3 182 ? 139.092 149.677 97.220  1.00 57.67  ? 182 THR A C   1 
ATOM 3378 O O   . THR C 3 182 ? 139.931 149.652 98.121  1.00 57.67  ? 182 THR A O   1 
ATOM 3379 C CB  . THR C 3 182 ? 140.653 149.836 95.276  1.00 57.67  ? 182 THR A CB  1 
ATOM 3380 O OG1 . THR C 3 182 ? 141.650 149.644 96.288  1.00 57.67  ? 182 THR A OG1 1 
ATOM 3381 C CG2 . THR C 3 182 ? 141.191 150.782 94.213  1.00 57.67  ? 182 THR A CG2 1 
ATOM 3382 N N   . GLY C 3 183 ? 137.907 149.080 97.316  1.00 54.34  ? 183 GLY A N   1 
ATOM 3383 C CA  . GLY C 3 183 ? 137.526 148.339 98.501  1.00 54.34  ? 183 GLY A CA  1 
ATOM 3384 C C   . GLY C 3 183 ? 137.166 149.224 99.676  1.00 54.34  ? 183 GLY A C   1 
ATOM 3385 O O   . GLY C 3 183 ? 136.581 150.298 99.499  1.00 54.34  ? 183 GLY A O   1 
ATOM 3386 N N   . ILE C 3 184 ? 137.510 148.786 100.880 1.00 54.05  ? 184 ILE A N   1 
ATOM 3387 C CA  . ILE C 3 184 ? 137.203 149.522 102.099 1.00 54.05  ? 184 ILE A CA  1 
ATOM 3388 C C   . ILE C 3 184 ? 138.191 150.670 102.238 1.00 54.05  ? 184 ILE A C   1 
ATOM 3389 O O   . ILE C 3 184 ? 139.403 150.487 102.073 1.00 54.05  ? 184 ILE A O   1 
ATOM 3390 C CB  . ILE C 3 184 ? 137.256 148.595 103.328 1.00 54.05  ? 184 ILE A CB  1 
ATOM 3391 C CG1 . ILE C 3 184 ? 136.266 147.441 103.174 1.00 54.05  ? 184 ILE A CG1 1 
ATOM 3392 C CG2 . ILE C 3 184 ? 136.939 149.372 104.594 1.00 54.05  ? 184 ILE A CG2 1 
ATOM 3393 C CD1 . ILE C 3 184 ? 134.834 147.875 103.056 1.00 54.05  ? 184 ILE A CD1 1 
ATOM 3394 N N   . VAL C 3 185 ? 137.679 151.858 102.542 1.00 58.53  ? 185 VAL A N   1 
ATOM 3395 C CA  . VAL C 3 185 ? 138.509 153.040 102.746 1.00 58.53  ? 185 VAL A CA  1 
ATOM 3396 C C   . VAL C 3 185 ? 138.792 153.165 104.237 1.00 58.53  ? 185 VAL A C   1 
ATOM 3397 O O   . VAL C 3 185 ? 137.865 153.163 105.055 1.00 58.53  ? 185 VAL A O   1 
ATOM 3398 C CB  . VAL C 3 185 ? 137.832 154.307 102.200 1.00 58.53  ? 185 VAL A CB  1 
ATOM 3399 C CG1 . VAL C 3 185 ? 138.821 155.462 102.167 1.00 58.53  ? 185 VAL A CG1 1 
ATOM 3400 C CG2 . VAL C 3 185 ? 137.261 154.047 100.815 1.00 58.53  ? 185 VAL A CG2 1 
ATOM 3401 N N   . GLU C 3 186 ? 140.071 153.279 104.586 1.00 58.51  ? 186 GLU A N   1 
ATOM 3402 C CA  . GLU C 3 186 ? 140.514 153.331 105.973 1.00 58.51  ? 186 GLU A CA  1 
ATOM 3403 C C   . GLU C 3 186 ? 140.779 154.775 106.376 1.00 58.51  ? 186 GLU A C   1 
ATOM 3404 O O   . GLU C 3 186 ? 141.459 155.509 105.652 1.00 58.51  ? 186 GLU A O   1 
ATOM 3405 C CB  . GLU C 3 186 ? 141.788 152.502 106.168 1.00 58.51  ? 186 GLU A CB  1 
ATOM 3406 C CG  . GLU C 3 186 ? 141.712 151.010 105.809 1.00 58.51  ? 186 GLU A CG  1 
ATOM 3407 C CD  . GLU C 3 186 ? 140.373 150.345 106.098 1.00 58.51  ? 186 GLU A CD  1 
ATOM 3408 O OE1 . GLU C 3 186 ? 140.024 149.399 105.362 1.00 58.51  ? 186 GLU A OE1 1 
ATOM 3409 O OE2 . GLU C 3 186 ? 139.701 150.708 107.086 1.00 58.51  ? 186 GLU A OE2 1 
ATOM 3410 N N   . THR C 3 187 ? 140.245 155.178 107.527 1.00 61.00  ? 187 THR A N   1 
ATOM 3411 C CA  . THR C 3 187 ? 140.579 156.463 108.127 1.00 61.00  ? 187 THR A CA  1 
ATOM 3412 C C   . THR C 3 187 ? 140.974 156.233 109.577 1.00 61.00  ? 187 THR A C   1 
ATOM 3413 O O   . THR C 3 187 ? 140.245 155.571 110.318 1.00 61.00  ? 187 THR A O   1 
ATOM 3414 C CB  . THR C 3 187 ? 139.404 157.443 108.045 1.00 61.00  ? 187 THR A CB  1 
ATOM 3415 O OG1 . THR C 3 187 ? 138.996 157.587 106.679 1.00 61.00  ? 187 THR A OG1 1 
ATOM 3416 C CG2 . THR C 3 187 ? 139.805 158.804 108.594 1.00 61.00  ? 187 THR A CG2 1 
ATOM 3417 N N   . HIS C 3 188 ? 142.124 156.762 109.980 1.00 60.70  ? 188 HIS A N   1 
ATOM 3418 C CA  . HIS C 3 188 ? 142.601 156.635 111.350 1.00 60.70  ? 188 HIS A CA  1 
ATOM 3419 C C   . HIS C 3 188 ? 142.857 158.020 111.922 1.00 60.70  ? 188 HIS A C   1 
ATOM 3420 O O   . HIS C 3 188 ? 143.589 158.813 111.320 1.00 60.70  ? 188 HIS A O   1 
ATOM 3421 C CB  . HIS C 3 188 ? 143.878 155.791 111.415 1.00 60.70  ? 188 HIS A CB  1 
ATOM 3422 C CG  . HIS C 3 188 ? 143.753 154.452 110.757 1.00 60.70  ? 188 HIS A CG  1 
ATOM 3423 N ND1 . HIS C 3 188 ? 143.434 153.308 111.455 1.00 60.70  ? 188 HIS A ND1 1 
ATOM 3424 C CD2 . HIS C 3 188 ? 143.904 154.075 109.466 1.00 60.70  ? 188 HIS A CD2 1 
ATOM 3425 C CE1 . HIS C 3 188 ? 143.394 152.283 110.622 1.00 60.70  ? 188 HIS A CE1 1 
ATOM 3426 N NE2 . HIS C 3 188 ? 143.675 152.722 109.409 1.00 60.70  ? 188 HIS A NE2 1 
ATOM 3427 N N   . PHE C 3 189 ? 142.261 158.312 113.077 1.00 59.91  ? 189 PHE A N   1 
ATOM 3428 C CA  . PHE C 3 189 ? 142.537 159.588 113.726 1.00 59.91  ? 189 PHE A CA  1 
ATOM 3429 C C   . PHE C 3 189 ? 142.315 159.477 115.227 1.00 59.91  ? 189 PHE A C   1 
ATOM 3430 O O   . PHE C 3 189 ? 141.409 158.776 115.678 1.00 59.91  ? 189 PHE A O   1 
ATOM 3431 C CB  . PHE C 3 189 ? 141.681 160.720 113.137 1.00 59.91  ? 189 PHE A CB  1 
ATOM 3432 C CG  . PHE C 3 189 ? 140.204 160.563 113.367 1.00 59.91  ? 189 PHE A CG  1 
ATOM 3433 C CD1 . PHE C 3 189 ? 139.442 159.755 112.541 1.00 59.91  ? 189 PHE A CD1 1 
ATOM 3434 C CD2 . PHE C 3 189 ? 139.574 161.244 114.396 1.00 59.91  ? 189 PHE A CD2 1 
ATOM 3435 C CE1 . PHE C 3 189 ? 138.082 159.616 112.744 1.00 59.91  ? 189 PHE A CE1 1 
ATOM 3436 C CE2 . PHE C 3 189 ? 138.214 161.109 114.605 1.00 59.91  ? 189 PHE A CE2 1 
ATOM 3437 C CZ  . PHE C 3 189 ? 137.467 160.296 113.777 1.00 59.91  ? 189 PHE A CZ  1 
ATOM 3438 N N   . THR C 3 190 ? 143.141 160.183 115.993 1.00 65.84  ? 190 THR A N   1 
ATOM 3439 C CA  . THR C 3 190 ? 143.093 160.149 117.449 1.00 65.84  ? 190 THR A CA  1 
ATOM 3440 C C   . THR C 3 190 ? 142.452 161.428 117.969 1.00 65.84  ? 190 THR A C   1 
ATOM 3441 O O   . THR C 3 190 ? 142.881 162.531 117.615 1.00 65.84  ? 190 THR A O   1 
ATOM 3442 C CB  . THR C 3 190 ? 144.495 159.984 118.041 1.00 65.84  ? 190 THR A CB  1 
ATOM 3443 O OG1 . THR C 3 190 ? 145.089 158.780 117.540 1.00 65.84  ? 190 THR A OG1 1 
ATOM 3444 C CG2 . THR C 3 190 ? 144.427 159.915 119.560 1.00 65.84  ? 190 THR A CG2 1 
ATOM 3445 N N   . PHE C 3 191 ? 141.428 161.275 118.808 1.00 63.26  ? 191 PHE A N   1 
ATOM 3446 C CA  . PHE C 3 191 ? 140.723 162.408 119.397 1.00 63.26  ? 191 PHE A CA  1 
ATOM 3447 C C   . PHE C 3 191 ? 140.412 162.090 120.850 1.00 63.26  ? 191 PHE A C   1 
ATOM 3448 O O   . PHE C 3 191 ? 139.738 161.095 121.135 1.00 63.26  ? 191 PHE A O   1 
ATOM 3449 C CB  . PHE C 3 191 ? 139.436 162.720 118.627 1.00 63.26  ? 191 PHE A CB  1 
ATOM 3450 C CG  . PHE C 3 191 ? 138.841 164.060 118.957 1.00 63.26  ? 191 PHE A CG  1 
ATOM 3451 C CD1 . PHE C 3 191 ? 139.481 165.228 118.579 1.00 63.26  ? 191 PHE A CD1 1 
ATOM 3452 C CD2 . PHE C 3 191 ? 137.642 164.149 119.643 1.00 63.26  ? 191 PHE A CD2 1 
ATOM 3453 C CE1 . PHE C 3 191 ? 138.936 166.462 118.881 1.00 63.26  ? 191 PHE A CE1 1 
ATOM 3454 C CE2 . PHE C 3 191 ? 137.092 165.380 119.949 1.00 63.26  ? 191 PHE A CE2 1 
ATOM 3455 C CZ  . PHE C 3 191 ? 137.740 166.538 119.566 1.00 63.26  ? 191 PHE A CZ  1 
ATOM 3456 N N   . LYS C 3 192 ? 140.898 162.936 121.759 1.00 61.55  ? 192 LYS A N   1 
ATOM 3457 C CA  . LYS C 3 192 ? 140.663 162.790 123.197 1.00 61.55  ? 192 LYS A CA  1 
ATOM 3458 C C   . LYS C 3 192 ? 141.103 161.414 123.695 1.00 61.55  ? 192 LYS A C   1 
ATOM 3459 O O   . LYS C 3 192 ? 140.368 160.713 124.395 1.00 61.55  ? 192 LYS A O   1 
ATOM 3460 C CB  . LYS C 3 192 ? 139.197 163.057 123.543 1.00 61.55  ? 192 LYS A CB  1 
ATOM 3461 C CG  . LYS C 3 192 ? 138.680 164.404 123.065 1.00 61.55  ? 192 LYS A CG  1 
ATOM 3462 C CD  . LYS C 3 192 ? 139.597 165.536 123.500 1.00 61.55  ? 192 LYS A CD  1 
ATOM 3463 C CE  . LYS C 3 192 ? 138.871 166.871 123.486 1.00 61.55  ? 192 LYS A CE  1 
ATOM 3464 N NZ  . LYS C 3 192 ? 137.584 166.810 124.232 1.00 61.55  ? 192 LYS A NZ  1 
ATOM 3465 N N   . ASP C 3 193 ? 142.327 161.032 123.321 1.00 59.14  ? 193 ASP A N   1 
ATOM 3466 C CA  . ASP C 3 193 ? 142.920 159.754 123.721 1.00 59.14  ? 193 ASP A CA  1 
ATOM 3467 C C   . ASP C 3 193 ? 142.038 158.577 123.309 1.00 59.14  ? 193 ASP A C   1 
ATOM 3468 O O   . ASP C 3 193 ? 141.848 157.623 124.066 1.00 59.14  ? 193 ASP A O   1 
ATOM 3469 C CB  . ASP C 3 193 ? 143.204 159.722 125.225 1.00 59.14  ? 193 ASP A CB  1 
ATOM 3470 C CG  . ASP C 3 193 ? 144.373 158.822 125.580 1.00 59.14  ? 193 ASP A CG  1 
ATOM 3471 O OD1 . ASP C 3 193 ? 144.586 157.813 124.876 1.00 59.14  ? 193 ASP A OD1 1 
ATOM 3472 O OD2 . ASP C 3 193 ? 145.078 159.123 126.566 1.00 59.14  ? 193 ASP A OD2 1 
ATOM 3473 N N   . LEU C 3 194 ? 141.492 158.647 122.098 1.00 58.58  ? 194 LEU A N   1 
ATOM 3474 C CA  . LEU C 3 194 ? 140.656 157.583 121.553 1.00 58.58  ? 194 LEU A CA  1 
ATOM 3475 C C   . LEU C 3 194 ? 140.950 157.458 120.068 1.00 58.58  ? 194 LEU A C   1 
ATOM 3476 O O   . LEU C 3 194 ? 140.763 158.419 119.315 1.00 58.58  ? 194 LEU A O   1 
ATOM 3477 C CB  . LEU C 3 194 ? 139.169 157.869 121.789 1.00 58.58  ? 194 LEU A CB  1 
ATOM 3478 C CG  . LEU C 3 194 ? 138.268 156.647 121.979 1.00 58.58  ? 194 LEU A CG  1 
ATOM 3479 C CD1 . LEU C 3 194 ? 138.808 155.747 123.080 1.00 58.58  ? 194 LEU A CD1 1 
ATOM 3480 C CD2 . LEU C 3 194 ? 136.840 157.073 122.281 1.00 58.58  ? 194 LEU A CD2 1 
ATOM 3481 N N   . HIS C 3 195 ? 141.409 156.282 119.648 1.00 60.25  ? 195 HIS A N   1 
ATOM 3482 C CA  . HIS C 3 195 ? 141.796 156.046 118.261 1.00 60.25  ? 195 HIS A CA  1 
ATOM 3483 C C   . HIS C 3 195 ? 140.575 155.576 117.479 1.00 60.25  ? 195 HIS A C   1 
ATOM 3484 O O   . HIS C 3 195 ? 140.112 154.442 117.654 1.00 60.25  ? 195 HIS A O   1 
ATOM 3485 C CB  . HIS C 3 195 ? 142.928 155.026 118.182 1.00 60.25  ? 195 HIS A CB  1 
ATOM 3486 C CG  . HIS C 3 195 ? 143.563 154.934 116.830 1.00 60.25  ? 195 HIS A CG  1 
ATOM 3487 N ND1 . HIS C 3 195 ? 143.431 153.828 116.019 1.00 60.25  ? 195 HIS A ND1 1 
ATOM 3488 C CD2 . HIS C 3 195 ? 144.335 155.812 116.146 1.00 60.25  ? 195 HIS A CD2 1 
ATOM 3489 C CE1 . HIS C 3 195 ? 144.094 154.027 114.894 1.00 60.25  ? 195 HIS A CE1 1 
ATOM 3490 N NE2 . HIS C 3 195 ? 144.652 155.224 114.946 1.00 60.25  ? 195 HIS A NE2 1 
ATOM 3491 N N   . PHE C 3 196 ? 140.057 156.447 116.616 1.00 58.01  ? 196 PHE A N   1 
ATOM 3492 C CA  . PHE C 3 196 ? 138.912 156.142 115.775 1.00 58.01  ? 196 PHE A CA  1 
ATOM 3493 C C   . PHE C 3 196 ? 139.389 155.605 114.432 1.00 58.01  ? 196 PHE A C   1 
ATOM 3494 O O   . PHE C 3 196 ? 140.224 156.231 113.761 1.00 58.01  ? 196 PHE A O   1 
ATOM 3495 C CB  . PHE C 3 196 ? 138.054 157.388 115.558 1.00 58.01  ? 196 PHE A CB  1 
ATOM 3496 C CG  . PHE C 3 196 ? 137.340 157.862 116.790 1.00 58.01  ? 196 PHE A CG  1 
ATOM 3497 C CD1 . PHE C 3 196 ? 137.983 158.672 117.711 1.00 58.01  ? 196 PHE A CD1 1 
ATOM 3498 C CD2 . PHE C 3 196 ? 136.020 157.516 117.016 1.00 58.01  ? 196 PHE A CD2 1 
ATOM 3499 C CE1 . PHE C 3 196 ? 137.327 159.114 118.842 1.00 58.01  ? 196 PHE A CE1 1 
ATOM 3500 C CE2 . PHE C 3 196 ? 135.359 157.955 118.144 1.00 58.01  ? 196 PHE A CE2 1 
ATOM 3501 C CZ  . PHE C 3 196 ? 136.013 158.756 119.059 1.00 58.01  ? 196 PHE A CZ  1 
ATOM 3502 N N   . LYS C 3 197 ? 138.859 154.443 114.055 1.00 59.91  ? 197 LYS A N   1 
ATOM 3503 C CA  . LYS C 3 197 ? 139.068 153.839 112.745 1.00 59.91  ? 197 LYS A CA  1 
ATOM 3504 C C   . LYS C 3 197 ? 137.733 153.854 112.011 1.00 59.91  ? 197 LYS A C   1 
ATOM 3505 O O   . LYS C 3 197 ? 136.808 153.121 112.376 1.00 59.91  ? 197 LYS A O   1 
ATOM 3506 C CB  . LYS C 3 197 ? 139.611 152.416 112.869 1.00 59.91  ? 197 LYS A CB  1 
ATOM 3507 C CG  . LYS C 3 197 ? 140.993 152.317 113.491 1.00 59.91  ? 197 LYS A CG  1 
ATOM 3508 C CD  . LYS C 3 197 ? 141.530 150.898 113.390 1.00 59.91  ? 197 LYS A CD  1 
ATOM 3509 C CE  . LYS C 3 197 ? 142.959 150.800 113.901 1.00 59.91  ? 197 LYS A CE  1 
ATOM 3510 N NZ  . LYS C 3 197 ? 143.034 150.921 115.382 1.00 59.91  ? 197 LYS A NZ  1 
ATOM 3511 N N   . MET C 3 198 ? 137.637 154.691 110.986 1.00 59.18  ? 198 MET A N   1 
ATOM 3512 C CA  . MET C 3 198 ? 136.437 154.823 110.173 1.00 59.18  ? 198 MET A CA  1 
ATOM 3513 C C   . MET C 3 198 ? 136.592 153.971 108.920 1.00 59.18  ? 198 MET A C   1 
ATOM 3514 O O   . MET C 3 198 ? 137.594 154.088 108.201 1.00 59.18  ? 198 MET A O   1 
ATOM 3515 C CB  . MET C 3 198 ? 136.189 156.284 109.803 1.00 59.18  ? 198 MET A CB  1 
ATOM 3516 C CG  . MET C 3 198 ? 135.567 157.112 110.915 1.00 59.18  ? 198 MET A CG  1 
ATOM 3517 S SD  . MET C 3 198 ? 134.896 158.680 110.331 1.00 59.18  ? 198 MET A SD  1 
ATOM 3518 C CE  . MET C 3 198 ? 136.027 159.059 108.993 1.00 59.18  ? 198 MET A CE  1 
ATOM 3519 N N   . PHE C 3 199 ? 135.604 153.115 108.667 1.00 52.26  ? 199 PHE A N   1 
ATOM 3520 C CA  . PHE C 3 199 ? 135.565 152.273 107.479 1.00 52.26  ? 199 PHE A CA  1 
ATOM 3521 C C   . PHE C 3 199 ? 134.529 152.857 106.527 1.00 52.26  ? 199 PHE A C   1 
ATOM 3522 O O   . PHE C 3 199 ? 133.330 152.843 106.823 1.00 52.26  ? 199 PHE A O   1 
ATOM 3523 C CB  . PHE C 3 199 ? 135.222 150.830 107.843 1.00 52.26  ? 199 PHE A CB  1 
ATOM 3524 C CG  . PHE C 3 199 ? 135.989 150.303 109.020 1.00 52.26  ? 199 PHE A CG  1 
ATOM 3525 C CD1 . PHE C 3 199 ? 137.371 150.247 108.996 1.00 52.26  ? 199 PHE A CD1 1 
ATOM 3526 C CD2 . PHE C 3 199 ? 135.325 149.859 110.152 1.00 52.26  ? 199 PHE A CD2 1 
ATOM 3527 C CE1 . PHE C 3 199 ? 138.079 149.761 110.079 1.00 52.26  ? 199 PHE A CE1 1 
ATOM 3528 C CE2 . PHE C 3 199 ? 136.027 149.372 111.237 1.00 52.26  ? 199 PHE A CE2 1 
ATOM 3529 C CZ  . PHE C 3 199 ? 137.406 149.323 111.201 1.00 52.26  ? 199 PHE A CZ  1 
ATOM 3530 N N   . ASP C 3 200 ? 134.991 153.374 105.393 1.00 61.56  ? 200 ASP A N   1 
ATOM 3531 C CA  . ASP C 3 200 ? 134.122 153.976 104.391 1.00 61.56  ? 200 ASP A CA  1 
ATOM 3532 C C   . ASP C 3 200 ? 133.877 152.974 103.271 1.00 61.56  ? 200 ASP A C   1 
ATOM 3533 O O   . ASP C 3 200 ? 134.815 152.325 102.795 1.00 61.56  ? 200 ASP A O   1 
ATOM 3534 C CB  . ASP C 3 200 ? 134.740 155.260 103.835 1.00 61.56  ? 200 ASP A CB  1 
ATOM 3535 C CG  . ASP C 3 200 ? 133.975 155.811 102.646 1.00 61.56  ? 200 ASP A CG  1 
ATOM 3536 O OD1 . ASP C 3 200 ? 132.738 155.646 102.600 1.00 61.56  ? 200 ASP A OD1 1 
ATOM 3537 O OD2 . ASP C 3 200 ? 134.613 156.411 101.755 1.00 61.56  ? 200 ASP A OD2 1 
ATOM 3538 N N   . VAL C 3 201 ? 132.622 152.853 102.854 1.00 66.12  ? 201 VAL A N   1 
ATOM 3539 C CA  . VAL C 3 201 ? 132.220 151.908 101.813 1.00 66.12  ? 201 VAL A CA  1 
ATOM 3540 C C   . VAL C 3 201 ? 131.668 152.726 100.649 1.00 66.12  ? 201 VAL A C   1 
ATOM 3541 O O   . VAL C 3 201 ? 130.481 153.061 100.588 1.00 66.12  ? 201 VAL A O   1 
ATOM 3542 C CB  . VAL C 3 201 ? 131.211 150.873 102.319 1.00 66.12  ? 201 VAL A CB  1 
ATOM 3543 C CG1 . VAL C 3 201 ? 131.906 149.855 103.199 1.00 66.12  ? 201 VAL A CG1 1 
ATOM 3544 C CG2 . VAL C 3 201 ? 130.101 151.537 103.117 1.00 66.12  ? 201 VAL A CG2 1 
ATOM 3545 N N   . THR C 3 202 ? 132.540 153.056 99.697  1.00 70.94  ? 202 THR A N   1 
ATOM 3546 C CA  . THR C 3 202 ? 132.123 153.701 98.460  1.00 70.94  ? 202 THR A CA  1 
ATOM 3547 C C   . THR C 3 202 ? 132.063 152.727 97.292  1.00 70.94  ? 202 THR A C   1 
ATOM 3548 O O   . THR C 3 202 ? 131.188 152.865 96.428  1.00 70.94  ? 202 THR A O   1 
ATOM 3549 C CB  . THR C 3 202 ? 133.076 154.857 98.120  1.00 70.94  ? 202 THR A CB  1 
ATOM 3550 O OG1 . THR C 3 202 ? 133.057 155.818 99.183  1.00 70.94  ? 202 THR A OG1 1 
ATOM 3551 C CG2 . THR C 3 202 ? 132.663 155.547 96.827  1.00 70.94  ? 202 THR A CG2 1 
ATOM 3552 N N   . ALA C 3 203 ? 132.948 151.732 97.268  1.00 69.87  ? 203 ALA A N   1 
ATOM 3553 C CA  . ALA C 3 203 ? 132.912 150.667 96.275  1.00 69.87  ? 203 ALA A CA  1 
ATOM 3554 C C   . ALA C 3 203 ? 131.996 149.546 96.746  1.00 69.87  ? 203 ALA A C   1 
ATOM 3555 O O   . ALA C 3 203 ? 131.202 149.735 97.673  1.00 69.87  ? 203 ALA A O   1 
ATOM 3556 C CB  . ALA C 3 203 ? 134.320 150.136 96.002  1.00 69.87  ? 203 ALA A CB  1 
ATOM 3557 N N   . GLN C 3 204 ? 132.094 148.381 96.102  1.00 63.10  ? 204 GLN A N   1 
ATOM 3558 C CA  . GLN C 3 204 ? 131.287 147.206 96.434  1.00 63.10  ? 204 GLN A CA  1 
ATOM 3559 C C   . GLN C 3 204 ? 129.795 147.497 96.262  1.00 63.10  ? 204 GLN A C   1 
ATOM 3560 O O   . GLN C 3 204 ? 129.008 147.465 97.211  1.00 63.10  ? 204 GLN A O   1 
ATOM 3561 C CB  . GLN C 3 204 ? 131.592 146.699 97.850  1.00 63.10  ? 204 GLN A CB  1 
ATOM 3562 C CG  . GLN C 3 204 ? 133.062 146.741 98.242  1.00 63.10  ? 204 GLN A CG  1 
ATOM 3563 C CD  . GLN C 3 204 ? 133.825 145.519 97.774  1.00 63.10  ? 204 GLN A CD  1 
ATOM 3564 O OE1 . GLN C 3 204 ? 133.265 144.634 97.127  1.00 63.10  ? 204 GLN A OE1 1 
ATOM 3565 N NE2 . GLN C 3 204 ? 135.110 145.460 98.104  1.00 63.10  ? 204 GLN A NE2 1 
ATOM 3566 N N   . ARG C 3 205 ? 129.417 147.783 95.014  1.00 68.55  ? 205 ARG A N   1 
ATOM 3567 C CA  . ARG C 3 205 ? 128.012 147.955 94.665  1.00 68.55  ? 205 ARG A CA  1 
ATOM 3568 C C   . ARG C 3 205 ? 127.253 146.635 94.620  1.00 68.55  ? 205 ARG A C   1 
ATOM 3569 O O   . ARG C 3 205 ? 126.088 146.624 94.208  1.00 68.55  ? 205 ARG A O   1 
ATOM 3570 C CB  . ARG C 3 205 ? 127.890 148.668 93.317  1.00 68.55  ? 205 ARG A CB  1 
ATOM 3571 N N   . SER C 3 206 ? 127.879 145.536 95.032  1.00 62.79  ? 206 SER A N   1 
ATOM 3572 C CA  . SER C 3 206 ? 127.244 144.228 95.020  1.00 62.79  ? 206 SER A CA  1 
ATOM 3573 C C   . SER C 3 206 ? 126.239 144.117 96.167  1.00 62.79  ? 206 SER A C   1 
ATOM 3574 O O   . SER C 3 206 ? 125.899 145.098 96.834  1.00 62.79  ? 206 SER A O   1 
ATOM 3575 C CB  . SER C 3 206 ? 128.302 143.131 95.108  1.00 62.79  ? 206 SER A CB  1 
ATOM 3576 O OG  . SER C 3 206 ? 129.240 143.410 96.133  1.00 62.79  ? 206 SER A OG  1 
ATOM 3577 N N   . GLU C 3 207 ? 125.746 142.897 96.384  1.00 59.71  ? 207 GLU A N   1 
ATOM 3578 C CA  . GLU C 3 207 ? 124.764 142.659 97.434  1.00 59.71  ? 207 GLU A CA  1 
ATOM 3579 C C   . GLU C 3 207 ? 125.324 143.055 98.795  1.00 59.71  ? 207 GLU A C   1 
ATOM 3580 O O   . GLU C 3 207 ? 126.454 142.704 99.146  1.00 59.71  ? 207 GLU A O   1 
ATOM 3581 C CB  . GLU C 3 207 ? 124.343 141.189 97.444  1.00 59.71  ? 207 GLU A CB  1 
ATOM 3582 N N   . ARG C 3 208 ? 124.517 143.792 99.560  1.00 55.95  ? 208 ARG A N   1 
ATOM 3583 C CA  . ARG C 3 208 ? 124.966 144.308 100.848 1.00 55.95  ? 208 ARG A CA  1 
ATOM 3584 C C   . ARG C 3 208 ? 125.085 143.200 101.885 1.00 55.95  ? 208 ARG A C   1 
ATOM 3585 O O   . ARG C 3 208 ? 126.050 143.164 102.657 1.00 55.95  ? 208 ARG A O   1 
ATOM 3586 C CB  . ARG C 3 208 ? 123.993 145.377 101.334 1.00 55.95  ? 208 ARG A CB  1 
ATOM 3587 C CG  . ARG C 3 208 ? 124.617 146.630 101.906 1.00 55.95  ? 208 ARG A CG  1 
ATOM 3588 C CD  . ARG C 3 208 ? 123.564 147.711 101.882 1.00 55.95  ? 208 ARG A CD  1 
ATOM 3589 N NE  . ARG C 3 208 ? 122.425 147.307 102.696 1.00 55.95  ? 208 ARG A NE  1 
ATOM 3590 C CZ  . ARG C 3 208 ? 121.203 147.807 102.584 1.00 55.95  ? 208 ARG A CZ  1 
ATOM 3591 N NH1 . ARG C 3 208 ? 120.905 148.704 101.659 1.00 55.95  ? 208 ARG A NH1 1 
ATOM 3592 N NH2 . ARG C 3 208 ? 120.250 147.376 103.404 1.00 55.95  ? 208 ARG A NH2 1 
ATOM 3593 N N   . LYS C 3 209 ? 124.112 142.285 101.917 1.00 55.24  ? 209 LYS A N   1 
ATOM 3594 C CA  . LYS C 3 209 ? 124.051 141.284 102.976 1.00 55.24  ? 209 LYS A CA  1 
ATOM 3595 C C   . LYS C 3 209 ? 125.199 140.286 102.907 1.00 55.24  ? 209 LYS A C   1 
ATOM 3596 O O   . LYS C 3 209 ? 125.420 139.547 103.872 1.00 55.24  ? 209 LYS A O   1 
ATOM 3597 C CB  . LYS C 3 209 ? 122.713 140.546 102.919 1.00 55.24  ? 209 LYS A CB  1 
ATOM 3598 C CG  . LYS C 3 209 ? 122.571 139.604 101.736 1.00 55.24  ? 209 LYS A CG  1 
ATOM 3599 C CD  . LYS C 3 209 ? 121.342 138.721 101.878 1.00 55.24  ? 209 LYS A CD  1 
ATOM 3600 C CE  . LYS C 3 209 ? 121.384 137.917 103.168 1.00 55.24  ? 209 LYS A CE  1 
ATOM 3601 N NZ  . LYS C 3 209 ? 122.633 137.116 103.286 1.00 55.24  ? 209 LYS A NZ  1 
ATOM 3602 N N   . LYS C 3 210 ? 125.930 140.242 101.792 1.00 52.63  ? 210 LYS A N   1 
ATOM 3603 C CA  . LYS C 3 210 ? 127.040 139.303 101.681 1.00 52.63  ? 210 LYS A CA  1 
ATOM 3604 C C   . LYS C 3 210 ? 128.240 139.745 102.510 1.00 52.63  ? 210 LYS A C   1 
ATOM 3605 O O   . LYS C 3 210 ? 129.045 138.905 102.926 1.00 52.63  ? 210 LYS A O   1 
ATOM 3606 C CB  . LYS C 3 210 ? 127.438 139.134 100.216 1.00 52.63  ? 210 LYS A CB  1 
ATOM 3607 C CG  . LYS C 3 210 ? 126.313 138.638 99.317  1.00 52.63  ? 210 LYS A CG  1 
ATOM 3608 C CD  . LYS C 3 210 ? 126.012 137.165 99.551  1.00 52.63  ? 210 LYS A CD  1 
ATOM 3609 C CE  . LYS C 3 210 ? 124.704 136.972 100.302 1.00 52.63  ? 210 LYS A CE  1 
ATOM 3610 N NZ  . LYS C 3 210 ? 124.344 135.534 100.433 1.00 52.63  ? 210 LYS A NZ  1 
ATOM 3611 N N   . TRP C 3 211 ? 128.378 141.047 102.760 1.00 51.48  ? 211 TRP A N   1 
ATOM 3612 C CA  . TRP C 3 211 ? 129.504 141.572 103.517 1.00 51.48  ? 211 TRP A CA  1 
ATOM 3613 C C   . TRP C 3 211 ? 129.094 142.420 104.713 1.00 51.48  ? 211 TRP A C   1 
ATOM 3614 O O   . TRP C 3 211 ? 129.971 142.860 105.466 1.00 51.48  ? 211 TRP A O   1 
ATOM 3615 C CB  . TRP C 3 211 ? 130.421 142.398 102.604 1.00 51.48  ? 211 TRP A CB  1 
ATOM 3616 C CG  . TRP C 3 211 ? 129.691 143.329 101.686 1.00 51.48  ? 211 TRP A CG  1 
ATOM 3617 C CD1 . TRP C 3 211 ? 129.185 143.035 100.454 1.00 51.48  ? 211 TRP A CD1 1 
ATOM 3618 C CD2 . TRP C 3 211 ? 129.391 144.709 101.925 1.00 51.48  ? 211 TRP A CD2 1 
ATOM 3619 N NE1 . TRP C 3 211 ? 128.584 144.145 99.912  1.00 51.48  ? 211 TRP A NE1 1 
ATOM 3620 C CE2 . TRP C 3 211 ? 128.697 145.186 100.795 1.00 51.48  ? 211 TRP A CE2 1 
ATOM 3621 C CE3 . TRP C 3 211 ? 129.639 145.587 102.984 1.00 51.48  ? 211 TRP A CE3 1 
ATOM 3622 C CZ2 . TRP C 3 211 ? 128.250 146.502 100.695 1.00 51.48  ? 211 TRP A CZ2 1 
ATOM 3623 C CZ3 . TRP C 3 211 ? 129.194 146.892 102.883 1.00 51.48  ? 211 TRP A CZ3 1 
ATOM 3624 C CH2 . TRP C 3 211 ? 128.508 147.337 101.747 1.00 51.48  ? 211 TRP A CH2 1 
ATOM 3625 N N   . ILE C 3 212 ? 127.798 142.667 104.912 1.00 51.91  ? 212 ILE A N   1 
ATOM 3626 C CA  . ILE C 3 212 ? 127.376 143.495 106.037 1.00 51.91  ? 212 ILE A CA  1 
ATOM 3627 C C   . ILE C 3 212 ? 127.578 142.761 107.359 1.00 51.91  ? 212 ILE A C   1 
ATOM 3628 O O   . ILE C 3 212 ? 127.866 143.389 108.386 1.00 51.91  ? 212 ILE A O   1 
ATOM 3629 C CB  . ILE C 3 212 ? 125.917 143.959 105.845 1.00 51.91  ? 212 ILE A CB  1 
ATOM 3630 C CG1 . ILE C 3 212 ? 125.655 145.239 106.639 1.00 51.91  ? 212 ILE A CG1 1 
ATOM 3631 C CG2 . ILE C 3 212 ? 124.926 142.867 106.230 1.00 51.91  ? 212 ILE A CG2 1 
ATOM 3632 C CD1 . ILE C 3 212 ? 126.497 146.415 106.196 1.00 51.91  ? 212 ILE A CD1 1 
ATOM 3633 N N   . HIS C 3 213 ? 127.455 141.430 107.360 1.00 49.79  ? 213 HIS A N   1 
ATOM 3634 C CA  . HIS C 3 213 ? 127.623 140.663 108.589 1.00 49.79  ? 213 HIS A CA  1 
ATOM 3635 C C   . HIS C 3 213 ? 129.046 140.738 109.126 1.00 49.79  ? 213 HIS A C   1 
ATOM 3636 O O   . HIS C 3 213 ? 129.263 140.470 110.313 1.00 49.79  ? 213 HIS A O   1 
ATOM 3637 C CB  . HIS C 3 213 ? 127.220 139.205 108.359 1.00 49.79  ? 213 HIS A CB  1 
ATOM 3638 C CG  . HIS C 3 213 ? 127.876 138.573 107.171 1.00 49.79  ? 213 HIS A CG  1 
ATOM 3639 N ND1 . HIS C 3 213 ? 129.230 138.325 107.111 1.00 49.79  ? 213 HIS A ND1 1 
ATOM 3640 C CD2 . HIS C 3 213 ? 127.362 138.138 105.997 1.00 49.79  ? 213 HIS A CD2 1 
ATOM 3641 C CE1 . HIS C 3 213 ? 129.522 137.764 105.951 1.00 49.79  ? 213 HIS A CE1 1 
ATOM 3642 N NE2 . HIS C 3 213 ? 128.406 137.640 105.256 1.00 49.79  ? 213 HIS A NE2 1 
ATOM 3643 N N   . CYS C 3 214 ? 130.017 141.093 108.283 1.00 48.51  ? 214 CYS A N   1 
ATOM 3644 C CA  . CYS C 3 214 ? 131.382 141.295 108.749 1.00 48.51  ? 214 CYS A CA  1 
ATOM 3645 C C   . CYS C 3 214 ? 131.542 142.573 109.559 1.00 48.51  ? 214 CYS A C   1 
ATOM 3646 O O   . CYS C 3 214 ? 132.590 142.762 110.184 1.00 48.51  ? 214 CYS A O   1 
ATOM 3647 C CB  . CYS C 3 214 ? 132.346 141.318 107.562 1.00 48.51  ? 214 CYS A CB  1 
ATOM 3648 S SG  . CYS C 3 214 ? 132.083 139.998 106.362 1.00 48.51  ? 214 CYS A SG  1 
ATOM 3649 N N   . PHE C 3 215 ? 130.537 143.451 109.564 1.00 48.50  ? 215 PHE A N   1 
ATOM 3650 C CA  . PHE C 3 215 ? 130.607 144.723 110.272 1.00 48.50  ? 215 PHE A CA  1 
ATOM 3651 C C   . PHE C 3 215 ? 129.842 144.699 111.590 1.00 48.50  ? 215 PHE A C   1 
ATOM 3652 O O   . PHE C 3 215 ? 129.387 145.746 112.062 1.00 48.50  ? 215 PHE A O   1 
ATOM 3653 C CB  . PHE C 3 215 ? 130.096 145.852 109.378 1.00 48.50  ? 215 PHE A CB  1 
ATOM 3654 C CG  . PHE C 3 215 ? 131.148 146.432 108.479 1.00 48.50  ? 215 PHE A CG  1 
ATOM 3655 C CD1 . PHE C 3 215 ? 132.052 147.364 108.961 1.00 48.50  ? 215 PHE A CD1 1 
ATOM 3656 C CD2 . PHE C 3 215 ? 131.241 146.039 107.155 1.00 48.50  ? 215 PHE A CD2 1 
ATOM 3657 C CE1 . PHE C 3 215 ? 133.024 147.898 108.138 1.00 48.50  ? 215 PHE A CE1 1 
ATOM 3658 C CE2 . PHE C 3 215 ? 132.211 146.569 106.327 1.00 48.50  ? 215 PHE A CE2 1 
ATOM 3659 C CZ  . PHE C 3 215 ? 133.103 147.499 106.819 1.00 48.50  ? 215 PHE A CZ  1 
ATOM 3660 N N   . GLU C 3 216 ? 129.691 143.526 112.197 1.00 51.83  ? 216 GLU A N   1 
ATOM 3661 C CA  . GLU C 3 216 ? 129.029 143.415 113.496 1.00 51.83  ? 216 GLU A CA  1 
ATOM 3662 C C   . GLU C 3 216 ? 130.054 143.544 114.625 1.00 51.83  ? 216 GLU A C   1 
ATOM 3663 O O   . GLU C 3 216 ? 130.082 142.786 115.594 1.00 51.83  ? 216 GLU A O   1 
ATOM 3664 C CB  . GLU C 3 216 ? 128.258 142.098 113.565 1.00 51.83  ? 216 GLU A CB  1 
ATOM 3665 C CG  . GLU C 3 216 ? 127.430 141.863 114.829 1.00 51.83  ? 216 GLU A CG  1 
ATOM 3666 C CD  . GLU C 3 216 ? 126.664 140.555 114.784 1.00 51.83  ? 216 GLU A CD  1 
ATOM 3667 O OE1 . GLU C 3 216 ? 126.794 139.824 113.780 1.00 51.83  ? 216 GLU A OE1 1 
ATOM 3668 O OE2 . GLU C 3 216 ? 125.934 140.258 115.752 1.00 51.83  ? 216 GLU A OE2 1 
ATOM 3669 N N   . GLY C 3 217 ? 130.944 144.523 114.475 1.00 55.17  ? 217 GLY A N   1 
ATOM 3670 C CA  . GLY C 3 217 ? 131.925 144.833 115.495 1.00 55.17  ? 217 GLY A CA  1 
ATOM 3671 C C   . GLY C 3 217 ? 132.169 146.321 115.633 1.00 55.17  ? 217 GLY A C   1 
ATOM 3672 O O   . GLY C 3 217 ? 133.003 146.750 116.436 1.00 55.17  ? 217 GLY A O   1 
ATOM 3673 N N   . VAL C 3 218 ? 131.443 147.118 114.856 1.00 50.32  ? 218 VAL A N   1 
ATOM 3674 C CA  . VAL C 3 218 ? 131.641 148.562 114.845 1.00 50.32  ? 218 VAL A CA  1 
ATOM 3675 C C   . VAL C 3 218 ? 130.904 149.185 116.021 1.00 50.32  ? 218 VAL A C   1 
ATOM 3676 O O   . VAL C 3 218 ? 129.808 148.748 116.396 1.00 50.32  ? 218 VAL A O   1 
ATOM 3677 C CB  . VAL C 3 218 ? 131.176 149.165 113.507 1.00 50.32  ? 218 VAL A CB  1 
ATOM 3678 C CG1 . VAL C 3 218 ? 132.090 148.715 112.379 1.00 50.32  ? 218 VAL A CG1 1 
ATOM 3679 C CG2 . VAL C 3 218 ? 129.732 148.782 113.218 1.00 50.32  ? 218 VAL A CG2 1 
ATOM 3680 N N   . THR C 3 219 ? 131.519 150.205 116.622 1.00 46.63  ? 219 THR A N   1 
ATOM 3681 C CA  . THR C 3 219 ? 130.876 150.910 117.725 1.00 46.63  ? 219 THR A CA  1 
ATOM 3682 C C   . THR C 3 219 ? 129.648 151.678 117.250 1.00 46.63  ? 219 THR A C   1 
ATOM 3683 O O   . THR C 3 219 ? 128.617 151.694 117.933 1.00 46.63  ? 219 THR A O   1 
ATOM 3684 C CB  . THR C 3 219 ? 131.874 151.851 118.399 1.00 46.63  ? 219 THR A CB  1 
ATOM 3685 O OG1 . THR C 3 219 ? 132.999 151.096 118.868 1.00 46.63  ? 219 THR A OG1 1 
ATOM 3686 C CG2 . THR C 3 219 ? 131.229 152.567 119.574 1.00 46.63  ? 219 THR A CG2 1 
ATOM 3687 N N   . ALA C 3 220 ? 129.732 152.314 116.083 1.00 45.27  ? 220 ALA A N   1 
ATOM 3688 C CA  . ALA C 3 220 ? 128.624 153.112 115.583 1.00 45.27  ? 220 ALA A CA  1 
ATOM 3689 C C   . ALA C 3 220 ? 128.648 153.145 114.061 1.00 45.27  ? 220 ALA A C   1 
ATOM 3690 O O   . ALA C 3 220 ? 129.677 152.899 113.422 1.00 45.27  ? 220 ALA A O   1 
ATOM 3691 C CB  . ALA C 3 220 ? 128.659 154.538 116.145 1.00 45.27  ? 220 ALA A CB  1 
ATOM 3692 N N   . ILE C 3 221 ? 127.486 153.457 113.492 1.00 43.83  ? 221 ILE A N   1 
ATOM 3693 C CA  . ILE C 3 221 ? 127.317 153.615 112.053 1.00 43.83  ? 221 ILE A CA  1 
ATOM 3694 C C   . ILE C 3 221 ? 126.914 155.059 111.791 1.00 43.83  ? 221 ILE A C   1 
ATOM 3695 O O   . ILE C 3 221 ? 125.892 155.526 112.306 1.00 43.83  ? 221 ILE A O   1 
ATOM 3696 C CB  . ILE C 3 221 ? 126.273 152.641 111.487 1.00 43.83  ? 221 ILE A CB  1 
ATOM 3697 C CG1 . ILE C 3 221 ? 126.812 151.210 111.507 1.00 43.83  ? 221 ILE A CG1 1 
ATOM 3698 C CG2 . ILE C 3 221 ? 125.877 153.043 110.075 1.00 43.83  ? 221 ILE A CG2 1 
ATOM 3699 C CD1 . ILE C 3 221 ? 125.782 150.166 111.139 1.00 43.83  ? 221 ILE A CD1 1 
ATOM 3700 N N   . ILE C 3 222 ? 127.710 155.758 110.990 1.00 41.50  ? 222 ILE A N   1 
ATOM 3701 C CA  . ILE C 3 222 ? 127.472 157.161 110.675 1.00 41.50  ? 222 ILE A CA  1 
ATOM 3702 C C   . ILE C 3 222 ? 126.693 157.228 109.367 1.00 41.50  ? 222 ILE A C   1 
ATOM 3703 O O   . ILE C 3 222 ? 127.205 156.863 108.305 1.00 41.50  ? 222 ILE A O   1 
ATOM 3704 C CB  . ILE C 3 222 ? 128.785 157.947 110.582 1.00 41.50  ? 222 ILE A CB  1 
ATOM 3705 C CG1 . ILE C 3 222 ? 129.525 157.907 111.922 1.00 41.50  ? 222 ILE A CG1 1 
ATOM 3706 C CG2 . ILE C 3 222 ? 128.515 159.382 110.156 1.00 41.50  ? 222 ILE A CG2 1 
ATOM 3707 C CD1 . ILE C 3 222 ? 130.639 158.926 112.043 1.00 41.50  ? 222 ILE A CD1 1 
ATOM 3708 N N   . PHE C 3 223 ? 125.451 157.695 109.446 1.00 48.67  ? 223 PHE A N   1 
ATOM 3709 C CA  . PHE C 3 223 ? 124.582 157.865 108.288 1.00 48.67  ? 223 PHE A CA  1 
ATOM 3710 C C   . PHE C 3 223 ? 124.552 159.345 107.927 1.00 48.67  ? 223 PHE A C   1 
ATOM 3711 O O   . PHE C 3 223 ? 123.985 160.157 108.663 1.00 48.67  ? 223 PHE A O   1 
ATOM 3712 C CB  . PHE C 3 223 ? 123.179 157.347 108.592 1.00 48.67  ? 223 PHE A CB  1 
ATOM 3713 C CG  . PHE C 3 223 ? 122.399 156.955 107.374 1.00 48.67  ? 223 PHE A CG  1 
ATOM 3714 C CD1 . PHE C 3 223 ? 121.748 157.910 106.614 1.00 48.67  ? 223 PHE A CD1 1 
ATOM 3715 C CD2 . PHE C 3 223 ? 122.312 155.632 106.991 1.00 48.67  ? 223 PHE A CD2 1 
ATOM 3716 C CE1 . PHE C 3 223 ? 121.026 157.549 105.493 1.00 48.67  ? 223 PHE A CE1 1 
ATOM 3717 C CE2 . PHE C 3 223 ? 121.592 155.266 105.875 1.00 48.67  ? 223 PHE A CE2 1 
ATOM 3718 C CZ  . PHE C 3 223 ? 120.949 156.226 105.123 1.00 48.67  ? 223 PHE A CZ  1 
ATOM 3719 N N   . CYS C 3 224 ? 125.152 159.692 106.793 1.00 55.74  ? 224 CYS A N   1 
ATOM 3720 C CA  . CYS C 3 224 ? 125.221 161.075 106.340 1.00 55.74  ? 224 CYS A CA  1 
ATOM 3721 C C   . CYS C 3 224 ? 124.169 161.304 105.263 1.00 55.74  ? 224 CYS A C   1 
ATOM 3722 O O   . CYS C 3 224 ? 124.159 160.610 104.240 1.00 55.74  ? 224 CYS A O   1 
ATOM 3723 C CB  . CYS C 3 224 ? 126.616 161.405 105.810 1.00 55.74  ? 224 CYS A CB  1 
ATOM 3724 S SG  . CYS C 3 224 ? 127.896 161.470 107.084 1.00 55.74  ? 224 CYS A SG  1 
ATOM 3725 N N   . VAL C 3 225 ? 123.287 162.274 105.494 1.00 60.24  ? 225 VAL A N   1 
ATOM 3726 C CA  . VAL C 3 225 ? 122.254 162.655 104.540 1.00 60.24  ? 225 VAL A CA  1 
ATOM 3727 C C   . VAL C 3 225 ? 122.481 164.109 104.157 1.00 60.24  ? 225 VAL A C   1 
ATOM 3728 O O   . VAL C 3 225 ? 122.559 164.980 105.030 1.00 60.24  ? 225 VAL A O   1 
ATOM 3729 C CB  . VAL C 3 225 ? 120.840 162.463 105.117 1.00 60.24  ? 225 VAL A CB  1 
ATOM 3730 C CG1 . VAL C 3 225 ? 119.793 162.956 104.130 1.00 60.24  ? 225 VAL A CG1 1 
ATOM 3731 C CG2 . VAL C 3 225 ? 120.603 161.010 105.466 1.00 60.24  ? 225 VAL A CG2 1 
ATOM 3732 N N   . ALA C 3 226 ? 122.580 164.369 102.858 1.00 71.44  ? 226 ALA A N   1 
ATOM 3733 C CA  . ALA C 3 226 ? 122.769 165.724 102.358 1.00 71.44  ? 226 ALA A CA  1 
ATOM 3734 C C   . ALA C 3 226 ? 121.407 166.383 102.183 1.00 71.44  ? 226 ALA A C   1 
ATOM 3735 O O   . ALA C 3 226 ? 120.569 165.895 101.417 1.00 71.44  ? 226 ALA A O   1 
ATOM 3736 C CB  . ALA C 3 226 ? 123.539 165.716 101.040 1.00 71.44  ? 226 ALA A CB  1 
ATOM 3737 N N   . LEU C 3 227 ? 121.190 167.487 102.891 1.00 76.32  ? 227 LEU A N   1 
ATOM 3738 C CA  . LEU C 3 227 ? 119.942 168.218 102.761 1.00 76.32  ? 227 LEU A CA  1 
ATOM 3739 C C   . LEU C 3 227 ? 119.897 168.952 101.421 1.00 76.32  ? 227 LEU A C   1 
ATOM 3740 O O   . LEU C 3 227 ? 120.859 168.952 100.646 1.00 76.32  ? 227 LEU A O   1 
ATOM 3741 C CB  . LEU C 3 227 ? 119.771 169.197 103.922 1.00 76.32  ? 227 LEU A CB  1 
ATOM 3742 C CG  . LEU C 3 227 ? 119.711 168.585 105.324 1.00 76.32  ? 227 LEU A CG  1 
ATOM 3743 C CD1 . LEU C 3 227 ? 119.774 169.670 106.387 1.00 76.32  ? 227 LEU A CD1 1 
ATOM 3744 C CD2 . LEU C 3 227 ? 118.457 167.741 105.489 1.00 76.32  ? 227 LEU A CD2 1 
ATOM 3745 N N   . SER C 3 228 ? 118.750 169.570 101.149 1.00 93.36  ? 228 SER A N   1 
ATOM 3746 C CA  . SER C 3 228 ? 118.448 170.250 99.891  1.00 93.36  ? 228 SER A CA  1 
ATOM 3747 C C   . SER C 3 228 ? 118.447 169.304 98.697  1.00 93.36  ? 228 SER A C   1 
ATOM 3748 O O   . SER C 3 228 ? 118.409 169.762 97.548  1.00 93.36  ? 228 SER A O   1 
ATOM 3749 C CB  . SER C 3 228 ? 119.411 171.418 99.629  1.00 93.36  ? 228 SER A CB  1 
ATOM 3750 O OG  . SER C 3 228 ? 120.661 170.951 99.154  1.00 93.36  ? 228 SER A OG  1 
ATOM 3751 N N   . ASP C 3 229 ? 118.492 167.995 98.935  1.00 95.99  ? 229 ASP A N   1 
ATOM 3752 C CA  . ASP C 3 229 ? 118.402 166.996 97.881  1.00 95.99  ? 229 ASP A CA  1 
ATOM 3753 C C   . ASP C 3 229 ? 116.992 166.450 97.713  1.00 95.99  ? 229 ASP A C   1 
ATOM 3754 O O   . ASP C 3 229 ? 116.788 165.530 96.914  1.00 95.99  ? 229 ASP A O   1 
ATOM 3755 C CB  . ASP C 3 229 ? 119.373 165.844 98.159  1.00 95.99  ? 229 ASP A CB  1 
ATOM 3756 N N   . TYR C 3 230 ? 116.018 166.988 98.451  1.00 100.74 ? 230 TYR A N   1 
ATOM 3757 C CA  . TYR C 3 230 ? 114.643 166.517 98.331  1.00 100.74 ? 230 TYR A CA  1 
ATOM 3758 C C   . TYR C 3 230 ? 114.078 166.802 96.944  1.00 100.74 ? 230 TYR A C   1 
ATOM 3759 O O   . TYR C 3 230 ? 113.359 165.971 96.378  1.00 100.74 ? 230 TYR A O   1 
ATOM 3760 C CB  . TYR C 3 230 ? 113.773 167.156 99.416  1.00 100.74 ? 230 TYR A CB  1 
ATOM 3761 C CG  . TYR C 3 230 ? 113.741 168.669 99.386  1.00 100.74 ? 230 TYR A CG  1 
ATOM 3762 C CD1 . TYR C 3 230 ? 114.735 169.418 100.002 1.00 100.74 ? 230 TYR A CD1 1 
ATOM 3763 C CD2 . TYR C 3 230 ? 112.709 169.349 98.750  1.00 100.74 ? 230 TYR A CD2 1 
ATOM 3764 C CE1 . TYR C 3 230 ? 114.708 170.800 99.979  1.00 100.74 ? 230 TYR A CE1 1 
ATOM 3765 C CE2 . TYR C 3 230 ? 112.674 170.730 98.722  1.00 100.74 ? 230 TYR A CE2 1 
ATOM 3766 C CZ  . TYR C 3 230 ? 113.675 171.450 99.338  1.00 100.74 ? 230 TYR A CZ  1 
ATOM 3767 O OH  . TYR C 3 230 ? 113.644 172.826 99.313  1.00 100.74 ? 230 TYR A OH  1 
ATOM 3768 N N   . ASP C 3 231 ? 114.390 167.972 96.382  1.00 101.27 ? 231 ASP A N   1 
ATOM 3769 C CA  . ASP C 3 231 ? 113.920 168.292 95.038  1.00 101.27 ? 231 ASP A CA  1 
ATOM 3770 C C   . ASP C 3 231 ? 114.662 167.489 93.977  1.00 101.27 ? 231 ASP A C   1 
ATOM 3771 O O   . ASP C 3 231 ? 114.090 167.176 92.927  1.00 101.27 ? 231 ASP A O   1 
ATOM 3772 C CB  . ASP C 3 231 ? 114.069 169.789 94.772  1.00 101.27 ? 231 ASP A CB  1 
ATOM 3773 C CG  . ASP C 3 231 ? 115.484 170.282 94.994  1.00 101.27 ? 231 ASP A CG  1 
ATOM 3774 O OD1 . ASP C 3 231 ? 115.950 170.247 96.152  1.00 101.27 ? 231 ASP A OD1 1 
ATOM 3775 O OD2 . ASP C 3 231 ? 116.130 170.703 94.012  1.00 101.27 ? 231 ASP A OD2 1 
ATOM 3776 N N   . LEU C 3 232 ? 115.925 167.154 94.228  1.00 97.01  ? 232 LEU A N   1 
ATOM 3777 C CA  . LEU C 3 232 ? 116.701 166.377 93.273  1.00 97.01  ? 232 LEU A CA  1 
ATOM 3778 C C   . LEU C 3 232 ? 116.146 164.962 93.151  1.00 97.01  ? 232 LEU A C   1 
ATOM 3779 O O   . LEU C 3 232 ? 115.673 164.367 94.123  1.00 97.01  ? 232 LEU A O   1 
ATOM 3780 C CB  . LEU C 3 232 ? 118.170 166.327 93.694  1.00 97.01  ? 232 LEU A CB  1 
ATOM 3781 C CG  . LEU C 3 232 ? 118.834 167.665 94.024  1.00 97.01  ? 232 LEU A CG  1 
ATOM 3782 C CD1 . LEU C 3 232 ? 120.304 167.466 94.359  1.00 97.01  ? 232 LEU A CD1 1 
ATOM 3783 C CD2 . LEU C 3 232 ? 118.672 168.645 92.873  1.00 97.01  ? 232 LEU A CD2 1 
ATOM 3784 N N   . VAL C 3 233 ? 116.209 164.424 91.936  1.00 94.20  ? 233 VAL A N   1 
ATOM 3785 C CA  . VAL C 3 233 ? 115.717 163.086 91.633  1.00 94.20  ? 233 VAL A CA  1 
ATOM 3786 C C   . VAL C 3 233 ? 116.857 162.267 91.045  1.00 94.20  ? 233 VAL A C   1 
ATOM 3787 O O   . VAL C 3 233 ? 117.677 162.783 90.277  1.00 94.20  ? 233 VAL A O   1 
ATOM 3788 C CB  . VAL C 3 233 ? 114.508 163.123 90.673  1.00 94.20  ? 233 VAL A CB  1 
ATOM 3789 C CG1 . VAL C 3 233 ? 113.334 163.832 91.329  1.00 94.20  ? 233 VAL A CG1 1 
ATOM 3790 C CG2 . VAL C 3 233 ? 114.876 163.810 89.366  1.00 94.20  ? 233 VAL A CG2 1 
ATOM 3791 N N   . LEU C 3 234 ? 116.918 160.995 91.424  1.00 95.25  ? 234 LEU A N   1 
ATOM 3792 C CA  . LEU C 3 234 ? 117.961 160.099 90.940  1.00 95.25  ? 234 LEU A CA  1 
ATOM 3793 C C   . LEU C 3 234 ? 117.498 158.647 90.985  1.00 95.25  ? 234 LEU A C   1 
ATOM 3794 O O   . LEU C 3 234 ? 117.548 158.001 92.032  1.00 95.25  ? 234 LEU A O   1 
ATOM 3795 C CB  . LEU C 3 234 ? 119.240 160.270 91.763  1.00 95.25  ? 234 LEU A CB  1 
ATOM 3796 N N   . ASN C 3 241 ? 113.655 162.172 94.950  1.00 90.77  ? 241 ASN A N   1 
ATOM 3797 C CA  . ASN C 3 241 ? 113.773 160.722 94.851  1.00 90.77  ? 241 ASN A CA  1 
ATOM 3798 C C   . ASN C 3 241 ? 114.979 160.219 95.637  1.00 90.77  ? 241 ASN A C   1 
ATOM 3799 O O   . ASN C 3 241 ? 114.986 159.088 96.124  1.00 90.77  ? 241 ASN A O   1 
ATOM 3800 C CB  . ASN C 3 241 ? 113.878 160.292 93.387  1.00 90.77  ? 241 ASN A CB  1 
ATOM 3801 C CG  . ASN C 3 241 ? 113.713 158.795 93.206  1.00 90.77  ? 241 ASN A CG  1 
ATOM 3802 O OD1 . ASN C 3 241 ? 112.599 158.297 93.043  1.00 90.77  ? 241 ASN A OD1 1 
ATOM 3803 N ND2 . ASN C 3 241 ? 114.825 158.069 93.233  1.00 90.77  ? 241 ASN A ND2 1 
ATOM 3804 N N   . ARG C 3 242 ? 116.004 161.068 95.751  1.00 88.63  ? 242 ARG A N   1 
ATOM 3805 C CA  . ARG C 3 242 ? 117.194 160.696 96.510  1.00 88.63  ? 242 ARG A CA  1 
ATOM 3806 C C   . ARG C 3 242 ? 116.874 160.514 97.989  1.00 88.63  ? 242 ARG A C   1 
ATOM 3807 O O   . ARG C 3 242 ? 117.401 159.602 98.638  1.00 88.63  ? 242 ARG A O   1 
ATOM 3808 C CB  . ARG C 3 242 ? 118.286 161.748 96.321  1.00 88.63  ? 242 ARG A CB  1 
ATOM 3809 N N   . MET C 3 243 ? 116.017 161.377 98.541  1.00 84.17  ? 243 MET A N   1 
ATOM 3810 C CA  . MET C 3 243 ? 115.640 161.251 99.944  1.00 84.17  ? 243 MET A CA  1 
ATOM 3811 C C   . MET C 3 243 ? 114.870 159.962 100.202 1.00 84.17  ? 243 MET A C   1 
ATOM 3812 O O   . MET C 3 243 ? 115.002 159.368 101.278 1.00 84.17  ? 243 MET A O   1 
ATOM 3813 C CB  . MET C 3 243 ? 114.817 162.466 100.376 1.00 84.17  ? 243 MET A CB  1 
ATOM 3814 C CG  . MET C 3 243 ? 114.397 162.452 101.836 1.00 84.17  ? 243 MET A CG  1 
ATOM 3815 S SD  . MET C 3 243 ? 115.531 163.380 102.889 1.00 84.17  ? 243 MET A SD  1 
ATOM 3816 C CE  . MET C 3 243 ? 115.240 165.051 102.314 1.00 84.17  ? 243 MET A CE  1 
ATOM 3817 N N   . HIS C 3 244 ? 114.069 159.512 99.234  1.00 84.48  ? 244 HIS A N   1 
ATOM 3818 C CA  . HIS C 3 244 ? 113.377 158.236 99.384  1.00 84.48  ? 244 HIS A CA  1 
ATOM 3819 C C   . HIS C 3 244 ? 114.367 157.081 99.474  1.00 84.48  ? 244 HIS A C   1 
ATOM 3820 O O   . HIS C 3 244 ? 114.206 156.177 100.303 1.00 84.48  ? 244 HIS A O   1 
ATOM 3821 C CB  . HIS C 3 244 ? 112.405 158.029 98.222  1.00 84.48  ? 244 HIS A CB  1 
ATOM 3822 C CG  . HIS C 3 244 ? 111.351 159.088 98.121  1.00 84.48  ? 244 HIS A CG  1 
ATOM 3823 N ND1 . HIS C 3 244 ? 111.324 160.015 97.102  1.00 84.48  ? 244 HIS A ND1 1 
ATOM 3824 C CD2 . HIS C 3 244 ? 110.290 159.368 98.914  1.00 84.48  ? 244 HIS A CD2 1 
ATOM 3825 C CE1 . HIS C 3 244 ? 110.290 160.820 97.270  1.00 84.48  ? 244 HIS A CE1 1 
ATOM 3826 N NE2 . HIS C 3 244 ? 109.646 160.449 98.362  1.00 84.48  ? 244 HIS A NE2 1 
ATOM 3827 N N   . ALA C 3 245 ? 115.406 157.099 98.635  1.00 79.56  ? 245 ALA A N   1 
ATOM 3828 C CA  . ALA C 3 245 ? 116.442 156.074 98.718  1.00 79.56  ? 245 ALA A CA  1 
ATOM 3829 C C   . ALA C 3 245 ? 117.196 156.162 100.039 1.00 79.56  ? 245 ALA A C   1 
ATOM 3830 O O   . ALA C 3 245 ? 117.575 155.135 100.618 1.00 79.56  ? 245 ALA A O   1 
ATOM 3831 C CB  . ALA C 3 245 ? 117.405 156.203 97.538  1.00 79.56  ? 245 ALA A CB  1 
ATOM 3832 N N   . SER C 3 246 ? 117.429 157.383 100.527 1.00 70.57  ? 246 SER A N   1 
ATOM 3833 C CA  . SER C 3 246 ? 118.083 157.549 101.821 1.00 70.57  ? 246 SER A CA  1 
ATOM 3834 C C   . SER C 3 246 ? 117.252 156.933 102.939 1.00 70.57  ? 246 SER A C   1 
ATOM 3835 O O   . SER C 3 246 ? 117.787 156.230 103.805 1.00 70.57  ? 246 SER A O   1 
ATOM 3836 C CB  . SER C 3 246 ? 118.335 159.031 102.095 1.00 70.57  ? 246 SER A CB  1 
ATOM 3837 O OG  . SER C 3 246 ? 118.885 159.674 100.959 1.00 70.57  ? 246 SER A OG  1 
ATOM 3838 N N   . MET C 3 247 ? 115.938 157.178 102.932 1.00 72.02  ? 247 MET A N   1 
ATOM 3839 C CA  . MET C 3 247 ? 115.066 156.565 103.930 1.00 72.02  ? 247 MET A CA  1 
ATOM 3840 C C   . MET C 3 247 ? 115.059 155.050 103.798 1.00 72.02  ? 247 MET A C   1 
ATOM 3841 O O   . MET C 3 247 ? 115.044 154.331 104.802 1.00 72.02  ? 247 MET A O   1 
ATOM 3842 C CB  . MET C 3 247 ? 113.639 157.099 103.817 1.00 72.02  ? 247 MET A CB  1 
ATOM 3843 C CG  . MET C 3 247 ? 113.487 158.592 103.933 1.00 72.02  ? 247 MET A CG  1 
ATOM 3844 S SD  . MET C 3 247 ? 111.735 158.995 103.993 1.00 72.02  ? 247 MET A SD  1 
ATOM 3845 C CE  . MET C 3 247 ? 111.291 158.893 102.263 1.00 72.02  ? 247 MET A CE  1 
ATOM 3846 N N   . LYS C 3 248 ? 115.036 154.545 102.563 1.00 66.88  ? 248 LYS A N   1 
ATOM 3847 C CA  . LYS C 3 248 ? 115.035 153.099 102.367 1.00 66.88  ? 248 LYS A CA  1 
ATOM 3848 C C   . LYS C 3 248 ? 116.292 152.467 102.951 1.00 66.88  ? 248 LYS A C   1 
ATOM 3849 O O   . LYS C 3 248 ? 116.215 151.466 103.673 1.00 66.88  ? 248 LYS A O   1 
ATOM 3850 C CB  . LYS C 3 248 ? 114.907 152.769 100.880 1.00 66.88  ? 248 LYS A CB  1 
ATOM 3851 N N   . LEU C 3 249 ? 117.457 153.056 102.671 1.00 61.31  ? 249 LEU A N   1 
ATOM 3852 C CA  . LEU C 3 249 ? 118.702 152.524 103.217 1.00 61.31  ? 249 LEU A CA  1 
ATOM 3853 C C   . LEU C 3 249 ? 118.740 152.643 104.737 1.00 61.31  ? 249 LEU A C   1 
ATOM 3854 O O   . LEU C 3 249 ? 119.182 151.715 105.427 1.00 61.31  ? 249 LEU A O   1 
ATOM 3855 C CB  . LEU C 3 249 ? 119.901 153.232 102.585 1.00 61.31  ? 249 LEU A CB  1 
ATOM 3856 C CG  . LEU C 3 249 ? 121.270 152.934 103.198 1.00 61.31  ? 249 LEU A CG  1 
ATOM 3857 C CD1 . LEU C 3 249 ? 121.731 151.542 102.831 1.00 61.31  ? 249 LEU A CD1 1 
ATOM 3858 C CD2 . LEU C 3 249 ? 122.290 153.951 102.732 1.00 61.31  ? 249 LEU A CD2 1 
ATOM 3859 N N   . PHE C 3 250 ? 118.279 153.777 105.276 1.00 58.78  ? 250 PHE A N   1 
ATOM 3860 C CA  . PHE C 3 250 ? 118.277 153.968 106.723 1.00 58.78  ? 250 PHE A CA  1 
ATOM 3861 C C   . PHE C 3 250 ? 117.386 152.945 107.415 1.00 58.78  ? 250 PHE A C   1 
ATOM 3862 O O   . PHE C 3 250 ? 117.772 152.367 108.437 1.00 58.78  ? 250 PHE A O   1 
ATOM 3863 C CB  . PHE C 3 250 ? 117.822 155.389 107.057 1.00 58.78  ? 250 PHE A CB  1 
ATOM 3864 C CG  . PHE C 3 250 ? 118.114 155.806 108.470 1.00 58.78  ? 250 PHE A CG  1 
ATOM 3865 C CD1 . PHE C 3 250 ? 119.366 156.282 108.821 1.00 58.78  ? 250 PHE A CD1 1 
ATOM 3866 C CD2 . PHE C 3 250 ? 117.134 155.730 109.446 1.00 58.78  ? 250 PHE A CD2 1 
ATOM 3867 C CE1 . PHE C 3 250 ? 119.636 156.669 110.119 1.00 58.78  ? 250 PHE A CE1 1 
ATOM 3868 C CE2 . PHE C 3 250 ? 117.399 156.116 110.745 1.00 58.78  ? 250 PHE A CE2 1 
ATOM 3869 C CZ  . PHE C 3 250 ? 118.652 156.586 111.083 1.00 58.78  ? 250 PHE A CZ  1 
ATOM 3870 N N   . ASP C 3 251 ? 116.192 152.704 106.870 1.00 63.12  ? 251 ASP A N   1 
ATOM 3871 C CA  . ASP C 3 251 ? 115.300 151.702 107.442 1.00 63.12  ? 251 ASP A CA  1 
ATOM 3872 C C   . ASP C 3 251 ? 115.884 150.302 107.308 1.00 63.12  ? 251 ASP A C   1 
ATOM 3873 O O   . ASP C 3 251 ? 115.750 149.478 108.220 1.00 63.12  ? 251 ASP A O   1 
ATOM 3874 C CB  . ASP C 3 251 ? 113.929 151.775 106.771 1.00 63.12  ? 251 ASP A CB  1 
ATOM 3875 C CG  . ASP C 3 251 ? 112.910 150.863 107.427 1.00 63.12  ? 251 ASP A CG  1 
ATOM 3876 O OD1 . ASP C 3 251 ? 112.455 151.184 108.545 1.00 63.12  ? 251 ASP A OD1 1 
ATOM 3877 O OD2 . ASP C 3 251 ? 112.566 149.825 106.824 1.00 63.12  ? 251 ASP A OD2 1 
ATOM 3878 N N   . SER C 3 252 ? 116.528 150.013 106.175 1.00 59.49  ? 252 SER A N   1 
ATOM 3879 C CA  . SER C 3 252 ? 117.068 148.677 105.956 1.00 59.49  ? 252 SER A CA  1 
ATOM 3880 C C   . SER C 3 252 ? 118.211 148.369 106.916 1.00 59.49  ? 252 SER A C   1 
ATOM 3881 O O   . SER C 3 252 ? 118.309 147.250 107.433 1.00 59.49  ? 252 SER A O   1 
ATOM 3882 C CB  . SER C 3 252 ? 117.527 148.534 104.506 1.00 59.49  ? 252 SER A CB  1 
ATOM 3883 O OG  . SER C 3 252 ? 118.642 149.366 104.239 1.00 59.49  ? 252 SER A OG  1 
ATOM 3884 N N   . ILE C 3 253 ? 119.087 149.343 107.172 1.00 59.23  ? 253 ILE A N   1 
ATOM 3885 C CA  . ILE C 3 253 ? 120.255 149.059 108.002 1.00 59.23  ? 253 ILE A CA  1 
ATOM 3886 C C   . ILE C 3 253 ? 119.929 149.229 109.483 1.00 59.23  ? 253 ILE A C   1 
ATOM 3887 O O   . ILE C 3 253 ? 120.413 148.468 110.328 1.00 59.23  ? 253 ILE A O   1 
ATOM 3888 C CB  . ILE C 3 253 ? 121.455 149.929 107.583 1.00 59.23  ? 253 ILE A CB  1 
ATOM 3889 C CG1 . ILE C 3 253 ? 121.163 151.414 107.792 1.00 59.23  ? 253 ILE A CG1 1 
ATOM 3890 C CG2 . ILE C 3 253 ? 121.823 149.660 106.132 1.00 59.23  ? 253 ILE A CG2 1 
ATOM 3891 C CD1 . ILE C 3 253 ? 122.375 152.286 107.636 1.00 59.23  ? 253 ILE A CD1 1 
ATOM 3892 N N   . CYS C 3 254 ? 119.119 150.235 109.825 1.00 63.10  ? 254 CYS A N   1 
ATOM 3893 C CA  . CYS C 3 254 ? 118.773 150.462 111.224 1.00 63.10  ? 254 CYS A CA  1 
ATOM 3894 C C   . CYS C 3 254 ? 117.945 149.311 111.780 1.00 63.10  ? 254 CYS A C   1 
ATOM 3895 O O   . CYS C 3 254 ? 118.173 148.858 112.908 1.00 63.10  ? 254 CYS A O   1 
ATOM 3896 C CB  . CYS C 3 254 ? 118.023 151.786 111.368 1.00 63.10  ? 254 CYS A CB  1 
ATOM 3897 S SG  . CYS C 3 254 ? 117.188 152.009 112.953 1.00 63.10  ? 254 CYS A SG  1 
ATOM 3898 N N   . ASN C 3 255 ? 116.981 148.825 111.005 1.00 62.90  ? 255 ASN A N   1 
ATOM 3899 C CA  . ASN C 3 255 ? 116.156 147.686 111.404 1.00 62.90  ? 255 ASN A CA  1 
ATOM 3900 C C   . ASN C 3 255 ? 116.731 146.376 110.875 1.00 62.90  ? 255 ASN A C   1 
ATOM 3901 O O   . ASN C 3 255 ? 116.052 145.597 110.206 1.00 62.90  ? 255 ASN A O   1 
ATOM 3902 C CB  . ASN C 3 255 ? 114.724 147.892 110.928 1.00 62.90  ? 255 ASN A CB  1 
ATOM 3903 C CG  . ASN C 3 255 ? 114.056 149.080 111.590 1.00 62.90  ? 255 ASN A CG  1 
ATOM 3904 O OD1 . ASN C 3 255 ? 114.256 149.336 112.778 1.00 62.90  ? 255 ASN A OD1 1 
ATOM 3905 N ND2 . ASN C 3 255 ? 113.259 149.815 110.824 1.00 62.90  ? 255 ASN A ND2 1 
ATOM 3906 N N   . ASN C 3 256 ? 118.001 146.127 111.176 1.00 61.17  ? 256 ASN A N   1 
ATOM 3907 C CA  . ASN C 3 256 ? 118.705 144.943 110.713 1.00 61.17  ? 256 ASN A CA  1 
ATOM 3908 C C   . ASN C 3 256 ? 119.106 144.074 111.898 1.00 61.17  ? 256 ASN A C   1 
ATOM 3909 O O   . ASN C 3 256 ? 119.318 144.559 113.013 1.00 61.17  ? 256 ASN A O   1 
ATOM 3910 C CB  . ASN C 3 256 ? 119.945 145.328 109.897 1.00 61.17  ? 256 ASN A CB  1 
ATOM 3911 C CG  . ASN C 3 256 ? 120.488 144.173 109.080 1.00 61.17  ? 256 ASN A CG  1 
ATOM 3912 O OD1 . ASN C 3 256 ? 120.745 143.091 109.605 1.00 61.17  ? 256 ASN A OD1 1 
ATOM 3913 N ND2 . ASN C 3 256 ? 120.668 144.399 107.784 1.00 61.17  ? 256 ASN A ND2 1 
ATOM 3914 N N   . LYS C 3 257 ? 119.204 142.769 111.638 1.00 56.84  ? 257 LYS A N   1 
ATOM 3915 C CA  . LYS C 3 257 ? 119.550 141.819 112.690 1.00 56.84  ? 257 LYS A CA  1 
ATOM 3916 C C   . LYS C 3 257 ? 120.985 142.003 113.175 1.00 56.84  ? 257 LYS A C   1 
ATOM 3917 O O   . LYS C 3 257 ? 121.254 141.884 114.375 1.00 56.84  ? 257 LYS A O   1 
ATOM 3918 C CB  . LYS C 3 257 ? 119.329 140.388 112.197 1.00 56.84  ? 257 LYS A CB  1 
ATOM 3919 C CG  . LYS C 3 257 ? 119.950 140.089 110.841 1.00 56.84  ? 257 LYS A CG  1 
ATOM 3920 C CD  . LYS C 3 257 ? 119.763 138.630 110.453 1.00 56.84  ? 257 LYS A CD  1 
ATOM 3921 C CE  . LYS C 3 257 ? 120.142 137.698 111.592 1.00 56.84  ? 257 LYS A CE  1 
ATOM 3922 N NZ  . LYS C 3 257 ? 121.613 137.662 111.815 1.00 56.84  ? 257 LYS A NZ  1 
ATOM 3923 N N   . TRP C 3 258 ? 121.918 142.288 112.262 1.00 55.67  ? 258 TRP A N   1 
ATOM 3924 C CA  . TRP C 3 258 ? 123.313 142.445 112.661 1.00 55.67  ? 258 TRP A CA  1 
ATOM 3925 C C   . TRP C 3 258 ? 123.512 143.691 113.516 1.00 55.67  ? 258 TRP A C   1 
ATOM 3926 O O   . TRP C 3 258 ? 124.296 143.676 114.472 1.00 55.67  ? 258 TRP A O   1 
ATOM 3927 C CB  . TRP C 3 258 ? 124.216 142.496 111.428 1.00 55.67  ? 258 TRP A CB  1 
ATOM 3928 C CG  . TRP C 3 258 ? 123.907 141.449 110.401 1.00 55.67  ? 258 TRP A CG  1 
ATOM 3929 C CD1 . TRP C 3 258 ? 123.311 141.641 109.190 1.00 55.67  ? 258 TRP A CD1 1 
ATOM 3930 C CD2 . TRP C 3 258 ? 124.175 140.046 110.498 1.00 55.67  ? 258 TRP A CD2 1 
ATOM 3931 N NE1 . TRP C 3 258 ? 123.193 140.445 108.525 1.00 55.67  ? 258 TRP A NE1 1 
ATOM 3932 C CE2 . TRP C 3 258 ? 123.716 139.450 109.307 1.00 55.67  ? 258 TRP A CE2 1 
ATOM 3933 C CE3 . TRP C 3 258 ? 124.759 139.235 111.476 1.00 55.67  ? 258 TRP A CE3 1 
ATOM 3934 C CZ2 . TRP C 3 258 ? 123.822 138.082 109.068 1.00 55.67  ? 258 TRP A CZ2 1 
ATOM 3935 C CZ3 . TRP C 3 258 ? 124.864 137.878 111.237 1.00 55.67  ? 258 TRP A CZ3 1 
ATOM 3936 C CH2 . TRP C 3 258 ? 124.398 137.315 110.043 1.00 55.67  ? 258 TRP A CH2 1 
ATOM 3937 N N   . PHE C 3 259 ? 122.813 144.777 113.190 1.00 57.45  ? 259 PHE A N   1 
ATOM 3938 C CA  . PHE C 3 259 ? 122.942 146.048 113.900 1.00 57.45  ? 259 PHE A CA  1 
ATOM 3939 C C   . PHE C 3 259 ? 121.805 146.268 114.889 1.00 57.45  ? 259 PHE A C   1 
ATOM 3940 O O   . PHE C 3 259 ? 121.340 147.397 115.069 1.00 57.45  ? 259 PHE A O   1 
ATOM 3941 C CB  . PHE C 3 259 ? 123.020 147.203 112.908 1.00 57.45  ? 259 PHE A CB  1 
ATOM 3942 C CG  . PHE C 3 259 ? 124.071 147.024 111.852 1.00 57.45  ? 259 PHE A CG  1 
ATOM 3943 C CD1 . PHE C 3 259 ? 125.369 146.691 112.200 1.00 57.45  ? 259 PHE A CD1 1 
ATOM 3944 C CD2 . PHE C 3 259 ? 123.762 147.189 110.513 1.00 57.45  ? 259 PHE A CD2 1 
ATOM 3945 C CE1 . PHE C 3 259 ? 126.340 146.525 111.232 1.00 57.45  ? 259 PHE A CE1 1 
ATOM 3946 C CE2 . PHE C 3 259 ? 124.728 147.025 109.540 1.00 57.45  ? 259 PHE A CE2 1 
ATOM 3947 C CZ  . PHE C 3 259 ? 126.019 146.692 109.900 1.00 57.45  ? 259 PHE A CZ  1 
ATOM 3948 N N   . THR C 3 260 ? 121.336 145.205 115.544 1.00 62.21  ? 260 THR A N   1 
ATOM 3949 C CA  . THR C 3 260 ? 120.262 145.334 116.521 1.00 62.21  ? 260 THR A CA  1 
ATOM 3950 C C   . THR C 3 260 ? 120.676 146.122 117.757 1.00 62.21  ? 260 THR A C   1 
ATOM 3951 O O   . THR C 3 260 ? 119.800 146.543 118.521 1.00 62.21  ? 260 THR A O   1 
ATOM 3952 C CB  . THR C 3 260 ? 119.758 143.949 116.937 1.00 62.21  ? 260 THR A CB  1 
ATOM 3953 O OG1 . THR C 3 260 ? 118.468 144.071 117.550 1.00 62.21  ? 260 THR A OG1 1 
ATOM 3954 C CG2 . THR C 3 260 ? 120.723 143.296 117.917 1.00 62.21  ? 260 THR A CG2 1 
ATOM 3955 N N   . ASP C 3 261 ? 121.976 146.332 117.973 1.00 60.16  ? 261 ASP A N   1 
ATOM 3956 C CA  . ASP C 3 261 ? 122.456 147.112 119.105 1.00 60.16  ? 261 ASP A CA  1 
ATOM 3957 C C   . ASP C 3 261 ? 123.403 148.240 118.721 1.00 60.16  ? 261 ASP A C   1 
ATOM 3958 O O   . ASP C 3 261 ? 123.666 149.106 119.562 1.00 60.16  ? 261 ASP A O   1 
ATOM 3959 C CB  . ASP C 3 261 ? 123.157 146.202 120.127 1.00 60.16  ? 261 ASP A CB  1 
ATOM 3960 C CG  . ASP C 3 261 ? 124.146 145.250 119.482 1.00 60.16  ? 261 ASP A CG  1 
ATOM 3961 O OD1 . ASP C 3 261 ? 124.500 145.460 118.303 1.00 60.16  ? 261 ASP A OD1 1 
ATOM 3962 O OD2 . ASP C 3 261 ? 124.570 144.288 120.156 1.00 60.16  ? 261 ASP A OD2 1 
ATOM 3963 N N   . THR C 3 262 ? 123.923 148.257 117.496 1.00 54.30  ? 262 THR A N   1 
ATOM 3964 C CA  . THR C 3 262 ? 124.817 149.326 117.074 1.00 54.30  ? 262 THR A CA  1 
ATOM 3965 C C   . THR C 3 262 ? 124.061 150.645 116.970 1.00 54.30  ? 262 THR A C   1 
ATOM 3966 O O   . THR C 3 262 ? 122.939 150.698 116.457 1.00 54.30  ? 262 THR A O   1 
ATOM 3967 C CB  . THR C 3 262 ? 125.461 148.981 115.731 1.00 54.30  ? 262 THR A CB  1 
ATOM 3968 O OG1 . THR C 3 262 ? 126.001 147.655 115.785 1.00 54.30  ? 262 THR A OG1 1 
ATOM 3969 C CG2 . THR C 3 262 ? 126.577 149.961 115.404 1.00 54.30  ? 262 THR A CG2 1 
ATOM 3970 N N   . SER C 3 263 ? 124.681 151.714 117.461 1.00 49.87  ? 263 SER A N   1 
ATOM 3971 C CA  . SER C 3 263 ? 124.070 153.034 117.448 1.00 49.87  ? 263 SER A CA  1 
ATOM 3972 C C   . SER C 3 263 ? 124.306 153.720 116.110 1.00 49.87  ? 263 SER A C   1 
ATOM 3973 O O   . SER C 3 263 ? 125.381 153.596 115.513 1.00 49.87  ? 263 SER A O   1 
ATOM 3974 C CB  . SER C 3 263 ? 124.625 153.899 118.579 1.00 49.87  ? 263 SER A CB  1 
ATOM 3975 O OG  . SER C 3 263 ? 125.842 154.514 118.195 1.00 49.87  ? 263 SER A OG  1 
ATOM 3976 N N   . ILE C 3 264 ? 123.295 154.451 115.649 1.00 46.77  ? 264 ILE A N   1 
ATOM 3977 C CA  . ILE C 3 264 ? 123.351 155.176 114.387 1.00 46.77  ? 264 ILE A CA  1 
ATOM 3978 C C   . ILE C 3 264 ? 123.483 156.663 114.685 1.00 46.77  ? 264 ILE A C   1 
ATOM 3979 O O   . ILE C 3 264 ? 122.673 157.233 115.428 1.00 46.77  ? 264 ILE A O   1 
ATOM 3980 C CB  . ILE C 3 264 ? 122.108 154.898 113.526 1.00 46.77  ? 264 ILE A CB  1 
ATOM 3981 C CG1 . ILE C 3 264 ? 121.792 153.401 113.508 1.00 46.77  ? 264 ILE A CG1 1 
ATOM 3982 C CG2 . ILE C 3 264 ? 122.315 155.416 112.113 1.00 46.77  ? 264 ILE A CG2 1 
ATOM 3983 C CD1 . ILE C 3 264 ? 122.857 152.557 112.848 1.00 46.77  ? 264 ILE A CD1 1 
ATOM 3984 N N   . ILE C 3 265 ? 124.506 157.286 114.112 1.00 43.59  ? 265 ILE A N   1 
ATOM 3985 C CA  . ILE C 3 265 ? 124.726 158.722 114.222 1.00 43.59  ? 265 ILE A CA  1 
ATOM 3986 C C   . ILE C 3 265 ? 124.326 159.343 112.891 1.00 43.59  ? 265 ILE A C   1 
ATOM 3987 O O   . ILE C 3 265 ? 125.013 159.166 111.880 1.00 43.59  ? 265 ILE A O   1 
ATOM 3988 C CB  . ILE C 3 265 ? 126.183 159.047 114.574 1.00 43.59  ? 265 ILE A CB  1 
ATOM 3989 C CG1 . ILE C 3 265 ? 126.589 158.348 115.872 1.00 43.59  ? 265 ILE A CG1 1 
ATOM 3990 C CG2 . ILE C 3 265 ? 126.378 160.550 114.692 1.00 43.59  ? 265 ILE A CG2 1 
ATOM 3991 C CD1 . ILE C 3 265 ? 128.082 158.322 116.105 1.00 43.59  ? 265 ILE A CD1 1 
ATOM 3992 N N   . LEU C 3 266 ? 123.213 160.068 112.885 1.00 49.12  ? 266 LEU A N   1 
ATOM 3993 C CA  . LEU C 3 266 ? 122.723 160.728 111.685 1.00 49.12  ? 266 LEU A CA  1 
ATOM 3994 C C   . LEU C 3 266 ? 123.328 162.122 111.587 1.00 49.12  ? 266 LEU A C   1 
ATOM 3995 O O   . LEU C 3 266 ? 123.315 162.881 112.561 1.00 49.12  ? 266 LEU A O   1 
ATOM 3996 C CB  . LEU C 3 266 ? 121.196 160.810 111.700 1.00 49.12  ? 266 LEU A CB  1 
ATOM 3997 C CG  . LEU C 3 266 ? 120.537 161.441 110.473 1.00 49.12  ? 266 LEU A CG  1 
ATOM 3998 C CD1 . LEU C 3 266 ? 120.381 160.417 109.361 1.00 49.12  ? 266 LEU A CD1 1 
ATOM 3999 C CD2 . LEU C 3 266 ? 119.194 162.049 110.840 1.00 49.12  ? 266 LEU A CD2 1 
ATOM 4000 N N   . PHE C 3 267 ? 123.870 162.444 110.416 1.00 50.92  ? 267 PHE A N   1 
ATOM 4001 C CA  . PHE C 3 267 ? 124.493 163.736 110.148 1.00 50.92  ? 267 PHE A CA  1 
ATOM 4002 C C   . PHE C 3 267 ? 123.774 164.373 108.967 1.00 50.92  ? 267 PHE A C   1 
ATOM 4003 O O   . PHE C 3 267 ? 123.894 163.898 107.832 1.00 50.92  ? 267 PHE A O   1 
ATOM 4004 C CB  . PHE C 3 267 ? 125.985 163.575 109.856 1.00 50.92  ? 267 PHE A CB  1 
ATOM 4005 C CG  . PHE C 3 267 ? 126.858 163.693 111.071 1.00 50.92  ? 267 PHE A CG  1 
ATOM 4006 C CD1 . PHE C 3 267 ? 126.922 164.878 111.784 1.00 50.92  ? 267 PHE A CD1 1 
ATOM 4007 C CD2 . PHE C 3 267 ? 127.619 162.618 111.498 1.00 50.92  ? 267 PHE A CD2 1 
ATOM 4008 C CE1 . PHE C 3 267 ? 127.726 164.988 112.902 1.00 50.92  ? 267 PHE A CE1 1 
ATOM 4009 C CE2 . PHE C 3 267 ? 128.425 162.722 112.615 1.00 50.92  ? 267 PHE A CE2 1 
ATOM 4010 C CZ  . PHE C 3 267 ? 128.479 163.908 113.317 1.00 50.92  ? 267 PHE A CZ  1 
ATOM 4011 N N   . LEU C 3 268 ? 123.034 165.448 109.231 1.00 58.08  ? 268 LEU A N   1 
ATOM 4012 C CA  . LEU C 3 268 ? 122.307 166.166 108.186 1.00 58.08  ? 268 LEU A CA  1 
ATOM 4013 C C   . LEU C 3 268 ? 123.196 167.297 107.684 1.00 58.08  ? 268 LEU A C   1 
ATOM 4014 O O   . LEU C 3 268 ? 123.291 168.356 108.309 1.00 58.08  ? 268 LEU A O   1 
ATOM 4015 C CB  . LEU C 3 268 ? 120.972 166.678 108.714 1.00 58.08  ? 268 LEU A CB  1 
ATOM 4016 C CG  . LEU C 3 268 ? 120.047 165.591 109.267 1.00 58.08  ? 268 LEU A CG  1 
ATOM 4017 C CD1 . LEU C 3 268 ? 119.024 166.174 110.228 1.00 58.08  ? 268 LEU A CD1 1 
ATOM 4018 C CD2 . LEU C 3 268 ? 119.357 164.844 108.134 1.00 58.08  ? 268 LEU A CD2 1 
ATOM 4019 N N   . ASN C 3 269 ? 123.850 167.070 106.549 1.00 65.49  ? 269 ASN A N   1 
ATOM 4020 C CA  . ASN C 3 269 ? 124.797 168.016 105.984 1.00 65.49  ? 269 ASN A CA  1 
ATOM 4021 C C   . ASN C 3 269 ? 124.104 168.948 104.992 1.00 65.49  ? 269 ASN A C   1 
ATOM 4022 O O   . ASN C 3 269 ? 122.917 168.810 104.691 1.00 65.49  ? 269 ASN A O   1 
ATOM 4023 C CB  . ASN C 3 269 ? 125.946 167.275 105.299 1.00 65.49  ? 269 ASN A CB  1 
ATOM 4024 C CG  . ASN C 3 269 ? 126.349 166.013 106.037 1.00 65.49  ? 269 ASN A CG  1 
ATOM 4025 O OD1 . ASN C 3 269 ? 126.647 166.044 107.230 1.00 65.49  ? 269 ASN A OD1 1 
ATOM 4026 N ND2 . ASN C 3 269 ? 126.360 164.891 105.326 1.00 65.49  ? 269 ASN A ND2 1 
ATOM 4027 N N   . LYS C 3 270 ? 124.878 169.908 104.479 1.00 75.35  ? 270 LYS A N   1 
ATOM 4028 C CA  . LYS C 3 270 ? 124.404 170.867 103.478 1.00 75.35  ? 270 LYS A CA  1 
ATOM 4029 C C   . LYS C 3 270 ? 123.178 171.634 103.971 1.00 75.35  ? 270 LYS A C   1 
ATOM 4030 O O   . LYS C 3 270 ? 122.226 171.868 103.223 1.00 75.35  ? 270 LYS A O   1 
ATOM 4031 C CB  . LYS C 3 270 ? 124.113 170.176 102.144 1.00 75.35  ? 270 LYS A CB  1 
ATOM 4032 N N   . LYS C 3 271 ? 123.201 172.029 105.246 1.00 79.74  ? 271 LYS A N   1 
ATOM 4033 C CA  . LYS C 3 271 ? 122.083 172.783 105.802 1.00 79.74  ? 271 LYS A CA  1 
ATOM 4034 C C   . LYS C 3 271 ? 122.071 174.225 105.307 1.00 79.74  ? 271 LYS A C   1 
ATOM 4035 O O   . LYS C 3 271 ? 120.997 174.825 105.177 1.00 79.74  ? 271 LYS A O   1 
ATOM 4036 C CB  . LYS C 3 271 ? 122.129 172.737 107.330 1.00 79.74  ? 271 LYS A CB  1 
ATOM 4037 C CG  . LYS C 3 271 ? 123.355 173.394 107.946 1.00 79.74  ? 271 LYS A CG  1 
ATOM 4038 C CD  . LYS C 3 271 ? 123.313 173.328 109.464 1.00 79.74  ? 271 LYS A CD  1 
ATOM 4039 C CE  . LYS C 3 271 ? 124.516 174.024 110.080 1.00 79.74  ? 271 LYS A CE  1 
ATOM 4040 N NZ  . LYS C 3 271 ? 124.489 173.964 111.568 1.00 79.74  ? 271 LYS A NZ  1 
ATOM 4041 N N   . ASP C 3 272 ? 123.247 174.796 105.029 1.00 86.33  ? 272 ASP A N   1 
ATOM 4042 C CA  . ASP C 3 272 ? 123.302 176.155 104.500 1.00 86.33  ? 272 ASP A CA  1 
ATOM 4043 C C   . ASP C 3 272 ? 122.628 176.241 103.137 1.00 86.33  ? 272 ASP A C   1 
ATOM 4044 O O   . ASP C 3 272 ? 121.883 177.188 102.861 1.00 86.33  ? 272 ASP A O   1 
ATOM 4045 C CB  . ASP C 3 272 ? 124.753 176.627 104.414 1.00 86.33  ? 272 ASP A CB  1 
ATOM 4046 N N   . LEU C 3 273 ? 122.881 175.259 102.269 1.00 91.69  ? 273 LEU A N   1 
ATOM 4047 C CA  . LEU C 3 273 ? 122.177 175.202 100.993 1.00 91.69  ? 273 LEU A CA  1 
ATOM 4048 C C   . LEU C 3 273 ? 120.705 174.860 101.188 1.00 91.69  ? 273 LEU A C   1 
ATOM 4049 O O   . LEU C 3 273 ? 119.855 175.325 100.421 1.00 91.69  ? 273 LEU A O   1 
ATOM 4050 C CB  . LEU C 3 273 ? 122.847 174.183 100.070 1.00 91.69  ? 273 LEU A CB  1 
ATOM 4051 C CG  . LEU C 3 273 ? 122.296 174.026 98.650  1.00 91.69  ? 273 LEU A CG  1 
ATOM 4052 C CD1 . LEU C 3 273 ? 122.027 175.382 98.011  1.00 91.69  ? 273 LEU A CD1 1 
ATOM 4053 C CD2 . LEU C 3 273 ? 123.250 173.206 97.793  1.00 91.69  ? 273 LEU A CD2 1 
ATOM 4054 N N   . PHE C 3 274 ? 120.391 174.051 102.203 1.00 91.34  ? 274 PHE A N   1 
ATOM 4055 C CA  . PHE C 3 274 ? 119.005 173.675 102.467 1.00 91.34  ? 274 PHE A CA  1 
ATOM 4056 C C   . PHE C 3 274 ? 118.161 174.889 102.832 1.00 91.34  ? 274 PHE A C   1 
ATOM 4057 O O   . PHE C 3 274 ? 117.012 175.013 102.388 1.00 91.34  ? 274 PHE A O   1 
ATOM 4058 C CB  . PHE C 3 274 ? 118.961 172.632 103.583 1.00 91.34  ? 274 PHE A CB  1 
ATOM 4059 C CG  . PHE C 3 274 ? 117.575 172.190 103.955 1.00 91.34  ? 274 PHE A CG  1 
ATOM 4060 C CD1 . PHE C 3 274 ? 116.857 171.344 103.127 1.00 91.34  ? 274 PHE A CD1 1 
ATOM 4061 C CD2 . PHE C 3 274 ? 116.997 172.607 105.142 1.00 91.34  ? 274 PHE A CD2 1 
ATOM 4062 C CE1 . PHE C 3 274 ? 115.585 170.930 103.472 1.00 91.34  ? 274 PHE A CE1 1 
ATOM 4063 C CE2 . PHE C 3 274 ? 115.725 172.198 105.492 1.00 91.34  ? 274 PHE A CE2 1 
ATOM 4064 C CZ  . PHE C 3 274 ? 115.019 171.357 104.657 1.00 91.34  ? 274 PHE A CZ  1 
ATOM 4065 N N   . GLU C 3 275 ? 118.712 175.792 103.646 1.00 95.69  ? 275 GLU A N   1 
ATOM 4066 C CA  . GLU C 3 275 ? 117.970 176.986 104.038 1.00 95.69  ? 275 GLU A CA  1 
ATOM 4067 C C   . GLU C 3 275 ? 117.644 177.853 102.828 1.00 95.69  ? 275 GLU A C   1 
ATOM 4068 O O   . GLU C 3 275 ? 116.537 178.395 102.723 1.00 95.69  ? 275 GLU A O   1 
ATOM 4069 C CB  . GLU C 3 275 ? 118.764 177.782 105.072 1.00 95.69  ? 275 GLU A CB  1 
ATOM 4070 N N   . GLU C 3 276 ? 118.597 177.999 101.905 1.00 97.72  ? 276 GLU A N   1 
ATOM 4071 C CA  . GLU C 3 276 ? 118.344 178.782 100.701 1.00 97.72  ? 276 GLU A CA  1 
ATOM 4072 C C   . GLU C 3 276 ? 117.363 178.075 99.773  1.00 97.72  ? 276 GLU A C   1 
ATOM 4073 O O   . GLU C 3 276 ? 116.528 178.725 99.134  1.00 97.72  ? 276 GLU A O   1 
ATOM 4074 C CB  . GLU C 3 276 ? 119.660 179.066 99.975  1.00 97.72  ? 276 GLU A CB  1 
ATOM 4075 N N   . LYS C 3 277 ? 117.447 176.746 99.686  1.00 103.44 ? 277 LYS A N   1 
ATOM 4076 C CA  . LYS C 3 277 ? 116.578 175.993 98.791  1.00 103.44 ? 277 LYS A CA  1 
ATOM 4077 C C   . LYS C 3 277 ? 115.139 175.923 99.282  1.00 103.44 ? 277 LYS A C   1 
ATOM 4078 O O   . LYS C 3 277 ? 114.227 175.790 98.459  1.00 103.44 ? 277 LYS A O   1 
ATOM 4079 C CB  . LYS C 3 277 ? 117.122 174.577 98.592  1.00 103.44 ? 277 LYS A CB  1 
ATOM 4080 C CG  . LYS C 3 277 ? 118.355 174.508 97.705  1.00 103.44 ? 277 LYS A CG  1 
ATOM 4081 C CD  . LYS C 3 277 ? 117.979 174.512 96.234  1.00 103.44 ? 277 LYS A CD  1 
ATOM 4082 C CE  . LYS C 3 277 ? 117.214 173.255 95.857  1.00 103.44 ? 277 LYS A CE  1 
ATOM 4083 N NZ  . LYS C 3 277 ? 117.864 172.029 96.396  1.00 103.44 ? 277 LYS A NZ  1 
ATOM 4084 N N   . ILE C 3 278 ? 114.913 175.998 100.596 1.00 104.13 ? 278 ILE A N   1 
ATOM 4085 C CA  . ILE C 3 278 ? 113.543 176.016 101.106 1.00 104.13 ? 278 ILE A CA  1 
ATOM 4086 C C   . ILE C 3 278 ? 112.800 177.246 100.601 1.00 104.13 ? 278 ILE A C   1 
ATOM 4087 O O   . ILE C 3 278 ? 111.629 177.165 100.208 1.00 104.13 ? 278 ILE A O   1 
ATOM 4088 C CB  . ILE C 3 278 ? 113.535 175.936 102.644 1.00 104.13 ? 278 ILE A CB  1 
ATOM 4089 C CG1 . ILE C 3 278 ? 114.003 174.555 103.103 1.00 104.13 ? 278 ILE A CG1 1 
ATOM 4090 C CG2 . ILE C 3 278 ? 112.149 176.237 103.195 1.00 104.13 ? 278 ILE A CG2 1 
ATOM 4091 C CD1 . ILE C 3 278 ? 113.121 173.430 102.607 1.00 104.13 ? 278 ILE A CD1 1 
ATOM 4092 N N   . LYS C 3 279 ? 113.467 178.403 100.597 1.00 108.20 ? 279 LYS A N   1 
ATOM 4093 C CA  . LYS C 3 279 ? 112.836 179.617 100.090 1.00 108.20 ? 279 LYS A CA  1 
ATOM 4094 C C   . LYS C 3 279 ? 112.499 179.502 98.609  1.00 108.20 ? 279 LYS A C   1 
ATOM 4095 O O   . LYS C 3 279 ? 111.541 180.127 98.140  1.00 108.20 ? 279 LYS A O   1 
ATOM 4096 C CB  . LYS C 3 279 ? 113.743 180.823 100.336 1.00 108.20 ? 279 LYS A CB  1 
ATOM 4097 N N   . LYS C 3 280 ? 113.268 178.713 97.858  1.00 110.96 ? 280 LYS A N   1 
ATOM 4098 C CA  . LYS C 3 280 ? 113.021 178.527 96.431  1.00 110.96 ? 280 LYS A CA  1 
ATOM 4099 C C   . LYS C 3 280 ? 112.160 177.293 96.168  1.00 110.96 ? 280 LYS A C   1 
ATOM 4100 O O   . LYS C 3 280 ? 111.095 177.391 95.549  1.00 110.96 ? 280 LYS A O   1 
ATOM 4101 C CB  . LYS C 3 280 ? 114.352 178.428 95.678  1.00 110.96 ? 280 LYS A CB  1 
ATOM 4102 N N   . SER C 3 281 ? 112.611 176.127 96.631  1.00 113.12 ? 281 SER A N   1 
ATOM 4103 C CA  . SER C 3 281 ? 111.884 174.885 96.419  1.00 113.12 ? 281 SER A CA  1 
ATOM 4104 C C   . SER C 3 281 ? 111.145 174.509 97.692  1.00 113.12 ? 281 SER A C   1 
ATOM 4105 O O   . SER C 3 281 ? 111.794 174.212 98.708  1.00 113.12 ? 281 SER A O   1 
ATOM 4106 C CB  . SER C 3 281 ? 112.839 173.767 96.006  1.00 113.12 ? 281 SER A CB  1 
ATOM 4107 O OG  . SER C 3 281 ? 113.424 174.035 94.744  1.00 113.12 ? 281 SER A OG  1 
ATOM 4108 N N   . PRO C 3 282 ? 109.815 174.510 97.699  1.00 116.17 ? 282 PRO A N   1 
ATOM 4109 C CA  . PRO C 3 282 ? 109.080 174.145 98.914  1.00 116.17 ? 282 PRO A CA  1 
ATOM 4110 C C   . PRO C 3 282 ? 109.272 172.679 99.269  1.00 116.17 ? 282 PRO A C   1 
ATOM 4111 O O   . PRO C 3 282 ? 109.649 171.846 98.442  1.00 116.17 ? 282 PRO A O   1 
ATOM 4112 C CB  . PRO C 3 282 ? 107.619 174.439 98.550  1.00 116.17 ? 282 PRO A CB  1 
ATOM 4113 C CG  . PRO C 3 282 ? 107.694 175.383 97.387  1.00 116.17 ? 282 PRO A CG  1 
ATOM 4114 C CD  . PRO C 3 282 ? 108.914 174.964 96.628  1.00 116.17 ? 282 PRO A CD  1 
ATOM 4115 N N   . LEU C 3 283 ? 109.002 172.373 100.536 1.00 113.82 ? 283 LEU A N   1 
ATOM 4116 C CA  . LEU C 3 283 ? 109.126 171.021 101.065 1.00 113.82 ? 283 LEU A CA  1 
ATOM 4117 C C   . LEU C 3 283 ? 107.886 170.171 100.769 1.00 113.82 ? 283 LEU A C   1 
ATOM 4118 O O   . LEU C 3 283 ? 107.643 169.167 101.443 1.00 113.82 ? 283 LEU A O   1 
ATOM 4119 C CB  . LEU C 3 283 ? 109.416 171.094 102.574 1.00 113.82 ? 283 LEU A CB  1 
ATOM 4120 C CG  . LEU C 3 283 ? 109.651 169.869 103.469 1.00 113.82 ? 283 LEU A CG  1 
ATOM 4121 C CD1 . LEU C 3 283 ? 110.558 168.859 102.782 1.00 113.82 ? 283 LEU A CD1 1 
ATOM 4122 C CD2 . LEU C 3 283 ? 110.231 170.286 104.811 1.00 113.82 ? 283 LEU A CD2 1 
ATOM 4123 N N   . THR C 3 284 ? 107.086 170.563 99.775  1.00 118.91 ? 284 THR A N   1 
ATOM 4124 C CA  . THR C 3 284 ? 105.911 169.783 99.406  1.00 118.91 ? 284 THR A CA  1 
ATOM 4125 C C   . THR C 3 284 ? 106.241 168.702 98.381  1.00 118.91 ? 284 THR A C   1 
ATOM 4126 O O   . THR C 3 284 ? 105.586 167.653 98.361  1.00 118.91 ? 284 THR A O   1 
ATOM 4127 C CB  . THR C 3 284 ? 104.819 170.712 98.869  1.00 118.91 ? 284 THR A CB  1 
ATOM 4128 O OG1 . THR C 3 284 ? 104.562 171.748 99.824  1.00 118.91 ? 284 THR A OG1 1 
ATOM 4129 C CG2 . THR C 3 284 ? 103.527 169.945 98.619  1.00 118.91 ? 284 THR A CG2 1 
ATOM 4130 N N   . ILE C 3 285 ? 107.254 168.928 97.539  1.00 117.61 ? 285 ILE A N   1 
ATOM 4131 C CA  . ILE C 3 285 ? 107.581 167.970 96.486  1.00 117.61 ? 285 ILE A CA  1 
ATOM 4132 C C   . ILE C 3 285 ? 108.044 166.644 97.084  1.00 117.61 ? 285 ILE A C   1 
ATOM 4133 O O   . ILE C 3 285 ? 107.704 165.568 96.578  1.00 117.61 ? 285 ILE A O   1 
ATOM 4134 C CB  . ILE C 3 285 ? 108.626 168.569 95.525  1.00 117.61 ? 285 ILE A CB  1 
ATOM 4135 C CG1 . ILE C 3 285 ? 108.959 167.580 94.405  1.00 117.61 ? 285 ILE A CG1 1 
ATOM 4136 C CG2 . ILE C 3 285 ? 109.881 169.007 96.275  1.00 117.61 ? 285 ILE A CG2 1 
ATOM 4137 C CD1 . ILE C 3 285 ? 109.760 168.187 93.273  1.00 117.61 ? 285 ILE A CD1 1 
ATOM 4138 N N   . CYS C 3 286 ? 108.818 166.697 98.165  1.00 110.67 ? 286 CYS A N   1 
ATOM 4139 C CA  . CYS C 3 286 ? 109.235 165.510 98.895  1.00 110.67 ? 286 CYS A CA  1 
ATOM 4140 C C   . CYS C 3 286 ? 108.811 165.664 100.347 1.00 110.67 ? 286 CYS A C   1 
ATOM 4141 O O   . CYS C 3 286 ? 108.676 166.784 100.847 1.00 110.67 ? 286 CYS A O   1 
ATOM 4142 C CB  . CYS C 3 286 ? 110.750 165.287 98.803  1.00 110.67 ? 286 CYS A CB  1 
ATOM 4143 S SG  . CYS C 3 286 ? 111.392 164.037 99.941  1.00 110.67 ? 286 CYS A SG  1 
ATOM 4144 N N   . TYR C 3 287 ? 108.604 164.529 101.020 1.00 97.45  ? 287 TYR A N   1 
ATOM 4145 C CA  . TYR C 3 287 ? 108.028 164.513 102.362 1.00 97.45  ? 287 TYR A CA  1 
ATOM 4146 C C   . TYR C 3 287 ? 106.656 165.176 102.351 1.00 97.45  ? 287 TYR A C   1 
ATOM 4147 O O   . TYR C 3 287 ? 106.507 166.302 102.843 1.00 97.45  ? 287 TYR A O   1 
ATOM 4148 C CB  . TYR C 3 287 ? 108.952 165.202 103.369 1.00 97.45  ? 287 TYR A CB  1 
ATOM 4149 C CG  . TYR C 3 287 ? 110.080 164.327 103.851 1.00 97.45  ? 287 TYR A CG  1 
ATOM 4150 C CD1 . TYR C 3 287 ? 109.957 162.948 103.848 1.00 97.45  ? 287 TYR A CD1 1 
ATOM 4151 C CD2 . TYR C 3 287 ? 111.272 164.877 104.295 1.00 97.45  ? 287 TYR A CD2 1 
ATOM 4152 C CE1 . TYR C 3 287 ? 110.981 162.144 104.286 1.00 97.45  ? 287 TYR A CE1 1 
ATOM 4153 C CE2 . TYR C 3 287 ? 112.308 164.075 104.733 1.00 97.45  ? 287 TYR A CE2 1 
ATOM 4154 C CZ  . TYR C 3 287 ? 112.157 162.708 104.726 1.00 97.45  ? 287 TYR A CZ  1 
ATOM 4155 O OH  . TYR C 3 287 ? 113.184 161.903 105.162 1.00 97.45  ? 287 TYR A OH  1 
ATOM 4156 N N   . PRO C 3 288 ? 105.632 164.518 101.789 1.00 105.65 ? 288 PRO A N   1 
ATOM 4157 C CA  . PRO C 3 288 ? 104.307 165.148 101.702 1.00 105.65 ? 288 PRO A CA  1 
ATOM 4158 C C   . PRO C 3 288 ? 103.664 165.372 103.062 1.00 105.65 ? 288 PRO A C   1 
ATOM 4159 O O   . PRO C 3 288 ? 104.271 165.096 104.102 1.00 105.65 ? 288 PRO A O   1 
ATOM 4160 C CB  . PRO C 3 288 ? 103.499 164.145 100.868 1.00 105.65 ? 288 PRO A CB  1 
ATOM 4161 C CG  . PRO C 3 288 ? 104.518 163.400 100.080 1.00 105.65 ? 288 PRO A CG  1 
ATOM 4162 C CD  . PRO C 3 288 ? 105.704 163.281 100.993 1.00 105.65 ? 288 PRO A CD  1 
ATOM 4163 N N   . GLU C 3 289 ? 102.423 165.865 103.057 1.00 110.02 ? 289 GLU A N   1 
ATOM 4164 C CA  . GLU C 3 289 ? 101.722 166.284 104.272 1.00 110.02 ? 289 GLU A CA  1 
ATOM 4165 C C   . GLU C 3 289 ? 102.534 167.304 105.065 1.00 110.02 ? 289 GLU A C   1 
ATOM 4166 O O   . GLU C 3 289 ? 102.552 167.279 106.298 1.00 110.02 ? 289 GLU A O   1 
ATOM 4167 C CB  . GLU C 3 289 ? 101.331 165.101 105.174 1.00 110.02 ? 289 GLU A CB  1 
ATOM 4168 C CG  . GLU C 3 289 ? 100.616 163.906 104.516 1.00 110.02 ? 289 GLU A CG  1 
ATOM 4169 C CD  . GLU C 3 289 ? 101.458 163.132 103.520 1.00 110.02 ? 289 GLU A CD  1 
ATOM 4170 O OE1 . GLU C 3 289 ? 100.975 162.891 102.394 1.00 110.02 ? 289 GLU A OE1 1 
ATOM 4171 O OE2 . GLU C 3 289 ? 102.592 162.743 103.871 1.00 110.02 ? 289 GLU A OE2 1 
ATOM 4172 N N   . TYR C 3 290 ? 103.211 168.209 104.362 1.00 112.02 ? 290 TYR A N   1 
ATOM 4173 C CA  . TYR C 3 290 ? 103.967 169.277 105.008 1.00 112.02 ? 290 TYR A CA  1 
ATOM 4174 C C   . TYR C 3 290 ? 103.043 170.460 105.269 1.00 112.02 ? 290 TYR A C   1 
ATOM 4175 O O   . TYR C 3 290 ? 102.703 171.208 104.347 1.00 112.02 ? 290 TYR A O   1 
ATOM 4176 C CB  . TYR C 3 290 ? 105.150 169.685 104.134 1.00 112.02 ? 290 TYR A CB  1 
ATOM 4177 C CG  . TYR C 3 290 ? 105.996 170.791 104.721 1.00 112.02 ? 290 TYR A CG  1 
ATOM 4178 C CD1 . TYR C 3 290 ? 106.601 170.646 105.962 1.00 112.02 ? 290 TYR A CD1 1 
ATOM 4179 C CD2 . TYR C 3 290 ? 106.195 171.979 104.030 1.00 112.02 ? 290 TYR A CD2 1 
ATOM 4180 C CE1 . TYR C 3 290 ? 107.376 171.654 106.501 1.00 112.02 ? 290 TYR A CE1 1 
ATOM 4181 C CE2 . TYR C 3 290 ? 106.970 172.993 104.560 1.00 112.02 ? 290 TYR A CE2 1 
ATOM 4182 C CZ  . TYR C 3 290 ? 107.557 172.825 105.796 1.00 112.02 ? 290 TYR A CZ  1 
ATOM 4183 O OH  . TYR C 3 290 ? 108.329 173.833 106.328 1.00 112.02 ? 290 TYR A OH  1 
ATOM 4184 N N   . ALA C 3 291 ? 102.635 170.632 106.527 1.00 113.28 ? 291 ALA A N   1 
ATOM 4185 C CA  . ALA C 3 291 ? 101.704 171.689 106.895 1.00 113.28 ? 291 ALA A CA  1 
ATOM 4186 C C   . ALA C 3 291 ? 102.387 172.949 107.406 1.00 113.28 ? 291 ALA A C   1 
ATOM 4187 O O   . ALA C 3 291 ? 101.752 174.009 107.435 1.00 113.28 ? 291 ALA A O   1 
ATOM 4188 C CB  . ALA C 3 291 ? 100.723 171.185 107.962 1.00 113.28 ? 291 ALA A CB  1 
ATOM 4189 N N   . GLY C 3 292 ? 103.655 172.864 107.806 1.00 114.20 ? 292 GLY A N   1 
ATOM 4190 C CA  . GLY C 3 292 ? 104.357 174.025 108.305 1.00 114.20 ? 292 GLY A CA  1 
ATOM 4191 C C   . GLY C 3 292 ? 104.747 174.995 107.206 1.00 114.20 ? 292 GLY A C   1 
ATOM 4192 O O   . GLY C 3 292 ? 104.725 174.683 106.016 1.00 114.20 ? 292 GLY A O   1 
ATOM 4193 N N   . SER C 3 293 ? 105.110 176.203 107.628 1.00 116.43 ? 293 SER A N   1 
ATOM 4194 C CA  . SER C 3 293 ? 105.531 177.230 106.689 1.00 116.43 ? 293 SER A CA  1 
ATOM 4195 C C   . SER C 3 293 ? 106.944 176.948 106.184 1.00 116.43 ? 293 SER A C   1 
ATOM 4196 O O   . SER C 3 293 ? 107.668 176.100 106.714 1.00 116.43 ? 293 SER A O   1 
ATOM 4197 C CB  . SER C 3 293 ? 105.471 178.611 107.341 1.00 116.43 ? 293 SER A CB  1 
ATOM 4198 O OG  . SER C 3 293 ? 105.909 179.618 106.445 1.00 116.43 ? 293 SER A OG  1 
ATOM 4199 N N   . ASN C 3 294 ? 107.333 177.678 105.140 1.00 115.97 ? 294 ASN A N   1 
ATOM 4200 C CA  . ASN C 3 294 ? 108.657 177.519 104.553 1.00 115.97 ? 294 ASN A CA  1 
ATOM 4201 C C   . ASN C 3 294 ? 109.720 178.172 105.428 1.00 115.97 ? 294 ASN A C   1 
ATOM 4202 O O   . ASN C 3 294 ? 110.327 179.174 105.036 1.00 115.97 ? 294 ASN A O   1 
ATOM 4203 C CB  . ASN C 3 294 ? 108.692 178.110 103.141 1.00 115.97 ? 294 ASN A CB  1 
ATOM 4204 C CG  . ASN C 3 294 ? 108.125 177.165 102.100 1.00 115.97 ? 294 ASN A CG  1 
ATOM 4205 O OD1 . ASN C 3 294 ? 108.414 175.969 102.107 1.00 115.97 ? 294 ASN A OD1 1 
ATOM 4206 N ND2 . ASN C 3 294 ? 107.311 177.700 101.197 1.00 115.97 ? 294 ASN A ND2 1 
ATOM 4207 N N   . THR C 3 295 ? 109.949 177.611 106.612 1.00 108.74 ? 295 THR A N   1 
ATOM 4208 C CA  . THR C 3 295 ? 110.941 178.115 107.549 1.00 108.74 ? 295 THR A CA  1 
ATOM 4209 C C   . THR C 3 295 ? 112.001 177.050 107.793 1.00 108.74 ? 295 THR A C   1 
ATOM 4210 O O   . THR C 3 295 ? 111.703 175.853 107.829 1.00 108.74 ? 295 THR A O   1 
ATOM 4211 C CB  . THR C 3 295 ? 110.299 178.525 108.881 1.00 108.74 ? 295 THR A CB  1 
ATOM 4212 O OG1 . THR C 3 295 ? 109.650 177.392 109.470 1.00 108.74 ? 295 THR A OG1 1 
ATOM 4213 C CG2 . THR C 3 295 ? 109.278 179.632 108.662 1.00 108.74 ? 295 THR A CG2 1 
ATOM 4214 N N   . TYR C 3 296 ? 113.247 177.501 107.957 1.00 99.02  ? 296 TYR A N   1 
ATOM 4215 C CA  . TYR C 3 296 ? 114.361 176.569 108.102 1.00 99.02  ? 296 TYR A CA  1 
ATOM 4216 C C   . TYR C 3 296 ? 114.243 175.743 109.378 1.00 99.02  ? 296 TYR A C   1 
ATOM 4217 O O   . TYR C 3 296 ? 114.484 174.531 109.363 1.00 99.02  ? 296 TYR A O   1 
ATOM 4218 C CB  . TYR C 3 296 ? 115.686 177.331 108.080 1.00 99.02  ? 296 TYR A CB  1 
ATOM 4219 C CG  . TYR C 3 296 ? 116.885 176.483 108.442 1.00 99.02  ? 296 TYR A CG  1 
ATOM 4220 C CD1 . TYR C 3 296 ? 117.111 175.260 107.821 1.00 99.02  ? 296 TYR A CD1 1 
ATOM 4221 C CD2 . TYR C 3 296 ? 117.785 176.901 109.412 1.00 99.02  ? 296 TYR A CD2 1 
ATOM 4222 C CE1 . TYR C 3 296 ? 118.202 174.481 108.154 1.00 99.02  ? 296 TYR A CE1 1 
ATOM 4223 C CE2 . TYR C 3 296 ? 118.879 176.129 109.751 1.00 99.02  ? 296 TYR A CE2 1 
ATOM 4224 C CZ  . TYR C 3 296 ? 119.082 174.921 109.119 1.00 99.02  ? 296 TYR A CZ  1 
ATOM 4225 O OH  . TYR C 3 296 ? 120.171 174.151 109.456 1.00 99.02  ? 296 TYR A OH  1 
ATOM 4226 N N   . GLU C 3 297 ? 113.878 176.380 110.493 1.00 98.26  ? 297 GLU A N   1 
ATOM 4227 C CA  . GLU C 3 297 ? 113.864 175.686 111.778 1.00 98.26  ? 297 GLU A CA  1 
ATOM 4228 C C   . GLU C 3 297 ? 112.824 174.571 111.794 1.00 98.26  ? 297 GLU A C   1 
ATOM 4229 O O   . GLU C 3 297 ? 113.121 173.428 112.164 1.00 98.26  ? 297 GLU A O   1 
ATOM 4230 C CB  . GLU C 3 297 ? 113.604 176.687 112.906 1.00 98.26  ? 297 GLU A CB  1 
ATOM 4231 N N   . GLU C 3 298 ? 111.592 174.888 111.389 1.00 97.38  ? 298 GLU A N   1 
ATOM 4232 C CA  . GLU C 3 298 ? 110.533 173.885 111.412 1.00 97.38  ? 298 GLU A CA  1 
ATOM 4233 C C   . GLU C 3 298 ? 110.775 172.796 110.374 1.00 97.38  ? 298 GLU A C   1 
ATOM 4234 O O   . GLU C 3 298 ? 110.485 171.623 110.632 1.00 97.38  ? 298 GLU A O   1 
ATOM 4235 C CB  . GLU C 3 298 ? 109.175 174.558 111.196 1.00 97.38  ? 298 GLU A CB  1 
ATOM 4236 C CG  . GLU C 3 298 ? 107.965 173.659 111.430 1.00 97.38  ? 298 GLU A CG  1 
ATOM 4237 C CD  . GLU C 3 298 ? 107.615 172.812 110.224 1.00 97.38  ? 298 GLU A CD  1 
ATOM 4238 O OE1 . GLU C 3 298 ? 107.896 173.252 109.090 1.00 97.38  ? 298 GLU A OE1 1 
ATOM 4239 O OE2 . GLU C 3 298 ? 107.060 171.708 110.410 1.00 97.38  ? 298 GLU A OE2 1 
ATOM 4240 N N   . ALA C 3 299 ? 111.316 173.157 109.208 1.00 94.16  ? 299 ALA A N   1 
ATOM 4241 C CA  . ALA C 3 299 ? 111.643 172.148 108.206 1.00 94.16  ? 299 ALA A CA  1 
ATOM 4242 C C   . ALA C 3 299 ? 112.721 171.198 108.712 1.00 94.16  ? 299 ALA A C   1 
ATOM 4243 O O   . ALA C 3 299 ? 112.625 169.981 108.520 1.00 94.16  ? 299 ALA A O   1 
ATOM 4244 C CB  . ALA C 3 299 ? 112.084 172.817 106.904 1.00 94.16  ? 299 ALA A CB  1 
ATOM 4245 N N   . ALA C 3 300 ? 113.756 171.735 109.364 1.00 86.12  ? 300 ALA A N   1 
ATOM 4246 C CA  . ALA C 3 300 ? 114.799 170.885 109.928 1.00 86.12  ? 300 ALA A CA  1 
ATOM 4247 C C   . ALA C 3 300 ? 114.259 169.994 111.039 1.00 86.12  ? 300 ALA A C   1 
ATOM 4248 O O   . ALA C 3 300 ? 114.649 168.823 111.139 1.00 86.12  ? 300 ALA A O   1 
ATOM 4249 C CB  . ALA C 3 300 ? 115.952 171.743 110.448 1.00 86.12  ? 300 ALA A CB  1 
ATOM 4250 N N   . ALA C 3 301 ? 113.370 170.527 111.881 1.00 84.25  ? 301 ALA A N   1 
ATOM 4251 C CA  . ALA C 3 301 ? 112.744 169.702 112.909 1.00 84.25  ? 301 ALA A CA  1 
ATOM 4252 C C   . ALA C 3 301 ? 111.928 168.577 112.286 1.00 84.25  ? 301 ALA A C   1 
ATOM 4253 O O   . ALA C 3 301 ? 111.944 167.441 112.775 1.00 84.25  ? 301 ALA A O   1 
ATOM 4254 C CB  . ALA C 3 301 ? 111.868 170.566 113.816 1.00 84.25  ? 301 ALA A CB  1 
ATOM 4255 N N   . TYR C 3 302 ? 111.206 168.875 111.202 1.00 80.66  ? 302 TYR A N   1 
ATOM 4256 C CA  . TYR C 3 302 ? 110.446 167.841 110.508 1.00 80.66  ? 302 TYR A CA  1 
ATOM 4257 C C   . TYR C 3 302 ? 111.368 166.785 109.911 1.00 80.66  ? 302 TYR A C   1 
ATOM 4258 O O   . TYR C 3 302 ? 111.059 165.590 109.952 1.00 80.66  ? 302 TYR A O   1 
ATOM 4259 C CB  . TYR C 3 302 ? 109.572 168.472 109.423 1.00 80.66  ? 302 TYR A CB  1 
ATOM 4260 C CG  . TYR C 3 302 ? 108.673 167.488 108.709 1.00 80.66  ? 302 TYR A CG  1 
ATOM 4261 C CD1 . TYR C 3 302 ? 107.488 167.054 109.289 1.00 80.66  ? 302 TYR A CD1 1 
ATOM 4262 C CD2 . TYR C 3 302 ? 109.006 166.996 107.454 1.00 80.66  ? 302 TYR A CD2 1 
ATOM 4263 C CE1 . TYR C 3 302 ? 106.662 166.155 108.641 1.00 80.66  ? 302 TYR A CE1 1 
ATOM 4264 C CE2 . TYR C 3 302 ? 108.185 166.097 106.798 1.00 80.66  ? 302 TYR A CE2 1 
ATOM 4265 C CZ  . TYR C 3 302 ? 107.015 165.681 107.396 1.00 80.66  ? 302 TYR A CZ  1 
ATOM 4266 O OH  . TYR C 3 302 ? 106.195 164.786 106.748 1.00 80.66  ? 302 TYR A OH  1 
ATOM 4267 N N   . ILE C 3 303 ? 112.501 167.210 109.344 1.00 79.33  ? 303 ILE A N   1 
ATOM 4268 C CA  . ILE C 3 303 ? 113.473 166.259 108.805 1.00 79.33  ? 303 ILE A CA  1 
ATOM 4269 C C   . ILE C 3 303 ? 113.973 165.336 109.909 1.00 79.33  ? 303 ILE A C   1 
ATOM 4270 O O   . ILE C 3 303 ? 114.031 164.108 109.748 1.00 79.33  ? 303 ILE A O   1 
ATOM 4271 C CB  . ILE C 3 303 ? 114.645 167.005 108.138 1.00 79.33  ? 303 ILE A CB  1 
ATOM 4272 C CG1 . ILE C 3 303 ? 114.166 167.848 106.955 1.00 79.33  ? 303 ILE A CG1 1 
ATOM 4273 C CG2 . ILE C 3 303 ? 115.717 166.021 107.690 1.00 79.33  ? 303 ILE A CG2 1 
ATOM 4274 C CD1 . ILE C 3 303 ? 113.417 167.079 105.914 1.00 79.33  ? 303 ILE A CD1 1 
ATOM 4275 N N   . GLN C 3 304 ? 114.339 165.920 111.053 1.00 71.84  ? 304 GLN A N   1 
ATOM 4276 C CA  . GLN C 3 304 ? 114.855 165.125 112.161 1.00 71.84  ? 304 GLN A CA  1 
ATOM 4277 C C   . GLN C 3 304 ? 113.803 164.155 112.684 1.00 71.84  ? 304 GLN A C   1 
ATOM 4278 O O   . GLN C 3 304 ? 114.118 163.001 112.988 1.00 71.84  ? 304 GLN A O   1 
ATOM 4279 C CB  . GLN C 3 304 ? 115.351 166.040 113.281 1.00 71.84  ? 304 GLN A CB  1 
ATOM 4280 C CG  . GLN C 3 304 ? 115.992 165.300 114.444 1.00 71.84  ? 304 GLN A CG  1 
ATOM 4281 C CD  . GLN C 3 304 ? 116.527 166.237 115.509 1.00 71.84  ? 304 GLN A CD  1 
ATOM 4282 O OE1 . GLN C 3 304 ? 117.109 165.799 116.502 1.00 71.84  ? 304 GLN A OE1 1 
ATOM 4283 N NE2 . GLN C 3 304 ? 116.334 167.535 115.307 1.00 71.84  ? 304 GLN A NE2 1 
ATOM 4284 N N   . CYS C 3 305 ? 112.549 164.601 112.790 1.00 75.51  ? 305 CYS A N   1 
ATOM 4285 C CA  . CYS C 3 305 ? 111.487 163.712 113.256 1.00 75.51  ? 305 CYS A CA  1 
ATOM 4286 C C   . CYS C 3 305 ? 111.226 162.585 112.262 1.00 75.51  ? 305 CYS A C   1 
ATOM 4287 O O   . CYS C 3 305 ? 111.018 161.432 112.662 1.00 75.51  ? 305 CYS A O   1 
ATOM 4288 C CB  . CYS C 3 305 ? 110.209 164.511 113.510 1.00 75.51  ? 305 CYS A CB  1 
ATOM 4289 S SG  . CYS C 3 305 ? 108.834 163.533 114.157 1.00 75.51  ? 305 CYS A SG  1 
ATOM 4290 N N   . GLN C 3 306 ? 111.224 162.900 110.963 1.00 74.66  ? 306 GLN A N   1 
ATOM 4291 C CA  . GLN C 3 306 ? 110.965 161.886 109.947 1.00 74.66  ? 306 GLN A CA  1 
ATOM 4292 C C   . GLN C 3 306 ? 112.101 160.879 109.855 1.00 74.66  ? 306 GLN A C   1 
ATOM 4293 O O   . GLN C 3 306 ? 111.884 159.739 109.428 1.00 74.66  ? 306 GLN A O   1 
ATOM 4294 C CB  . GLN C 3 306 ? 110.734 162.549 108.589 1.00 74.66  ? 306 GLN A CB  1 
ATOM 4295 C CG  . GLN C 3 306 ? 109.331 163.100 108.400 1.00 74.66  ? 306 GLN A CG  1 
ATOM 4296 C CD  . GLN C 3 306 ? 108.360 162.056 107.886 1.00 74.66  ? 306 GLN A CD  1 
ATOM 4297 O OE1 . GLN C 3 306 ? 107.365 161.742 108.540 1.00 74.66  ? 306 GLN A OE1 1 
ATOM 4298 N NE2 . GLN C 3 306 ? 108.645 161.511 106.709 1.00 74.66  ? 306 GLN A NE2 1 
ATOM 4299 N N   . PHE C 3 307 ? 113.316 161.279 110.223 1.00 67.10  ? 307 PHE A N   1 
ATOM 4300 C CA  . PHE C 3 307 ? 114.407 160.316 110.291 1.00 67.10  ? 307 PHE A CA  1 
ATOM 4301 C C   . PHE C 3 307 ? 114.437 159.555 111.611 1.00 67.10  ? 307 PHE A C   1 
ATOM 4302 O O   . PHE C 3 307 ? 114.900 158.409 111.647 1.00 67.10  ? 307 PHE A O   1 
ATOM 4303 C CB  . PHE C 3 307 ? 115.748 161.018 110.063 1.00 67.10  ? 307 PHE A CB  1 
ATOM 4304 C CG  . PHE C 3 307 ? 116.208 160.987 108.634 1.00 67.10  ? 307 PHE A CG  1 
ATOM 4305 C CD1 . PHE C 3 307 ? 116.730 159.828 108.085 1.00 67.10  ? 307 PHE A CD1 1 
ATOM 4306 C CD2 . PHE C 3 307 ? 116.109 162.115 107.836 1.00 67.10  ? 307 PHE A CD2 1 
ATOM 4307 C CE1 . PHE C 3 307 ? 117.150 159.796 106.769 1.00 67.10  ? 307 PHE A CE1 1 
ATOM 4308 C CE2 . PHE C 3 307 ? 116.528 162.089 106.520 1.00 67.10  ? 307 PHE A CE2 1 
ATOM 4309 C CZ  . PHE C 3 307 ? 117.049 160.928 105.986 1.00 67.10  ? 307 PHE A CZ  1 
ATOM 4310 N N   . GLU C 3 308 ? 113.952 160.166 112.694 1.00 69.25  ? 308 GLU A N   1 
ATOM 4311 C CA  . GLU C 3 308 ? 113.967 159.508 113.996 1.00 69.25  ? 308 GLU A CA  1 
ATOM 4312 C C   . GLU C 3 308 ? 112.888 158.437 114.092 1.00 69.25  ? 308 GLU A C   1 
ATOM 4313 O O   . GLU C 3 308 ? 113.135 157.338 114.602 1.00 69.25  ? 308 GLU A O   1 
ATOM 4314 C CB  . GLU C 3 308 ? 113.791 160.548 115.106 1.00 69.25  ? 308 GLU A CB  1 
ATOM 4315 C CG  . GLU C 3 308 ? 114.055 160.048 116.530 1.00 69.25  ? 308 GLU A CG  1 
ATOM 4316 C CD  . GLU C 3 308 ? 115.435 159.433 116.732 1.00 69.25  ? 308 GLU A CD  1 
ATOM 4317 O OE1 . GLU C 3 308 ? 115.657 158.835 117.806 1.00 69.25  ? 308 GLU A OE1 1 
ATOM 4318 O OE2 . GLU C 3 308 ? 116.313 159.583 115.856 1.00 69.25  ? 308 GLU A OE2 1 
ATOM 4319 N N   . ASP C 3 309 ? 111.680 158.737 113.606 1.00 69.98  ? 309 ASP A N   1 
ATOM 4320 C CA  . ASP C 3 309 ? 110.574 157.797 113.763 1.00 69.98  ? 309 ASP A CA  1 
ATOM 4321 C C   . ASP C 3 309 ? 110.701 156.575 112.862 1.00 69.98  ? 309 ASP A C   1 
ATOM 4322 O O   . ASP C 3 309 ? 109.930 155.624 113.028 1.00 69.98  ? 309 ASP A O   1 
ATOM 4323 C CB  . ASP C 3 309 ? 109.236 158.499 113.509 1.00 69.98  ? 309 ASP A CB  1 
ATOM 4324 C CG  . ASP C 3 309 ? 109.107 159.032 112.095 1.00 69.98  ? 309 ASP A CG  1 
ATOM 4325 O OD1 . ASP C 3 309 ? 110.105 159.006 111.348 1.00 69.98  ? 309 ASP A OD1 1 
ATOM 4326 O OD2 . ASP C 3 309 ? 107.999 159.477 111.730 1.00 69.98  ? 309 ASP A OD2 1 
ATOM 4327 N N   . LEU C 3 310 ? 111.643 156.579 111.916 1.00 69.31  ? 310 LEU A N   1 
ATOM 4328 C CA  . LEU C 3 310 ? 111.845 155.422 111.053 1.00 69.31  ? 310 LEU A CA  1 
ATOM 4329 C C   . LEU C 3 310 ? 112.372 154.214 111.818 1.00 69.31  ? 310 LEU A C   1 
ATOM 4330 O O   . LEU C 3 310 ? 112.180 153.079 111.369 1.00 69.31  ? 310 LEU A O   1 
ATOM 4331 C CB  . LEU C 3 310 ? 112.803 155.785 109.916 1.00 69.31  ? 310 LEU A CB  1 
ATOM 4332 C CG  . LEU C 3 310 ? 112.903 154.818 108.736 1.00 69.31  ? 310 LEU A CG  1 
ATOM 4333 C CD1 . LEU C 3 310 ? 111.553 154.658 108.055 1.00 69.31  ? 310 LEU A CD1 1 
ATOM 4334 C CD2 . LEU C 3 310 ? 113.950 155.302 107.746 1.00 69.31  ? 310 LEU A CD2 1 
ATOM 4335 N N   . ASN C 3 311 ? 113.025 154.431 112.958 1.00 69.07  ? 311 ASN A N   1 
ATOM 4336 C CA  . ASN C 3 311 ? 113.522 153.325 113.764 1.00 69.07  ? 311 ASN A CA  1 
ATOM 4337 C C   . ASN C 3 311 ? 112.362 152.527 114.349 1.00 69.07  ? 311 ASN A C   1 
ATOM 4338 O O   . ASN C 3 311 ? 111.340 153.088 114.754 1.00 69.07  ? 311 ASN A O   1 
ATOM 4339 C CB  . ASN C 3 311 ? 114.419 153.850 114.885 1.00 69.07  ? 311 ASN A CB  1 
ATOM 4340 C CG  . ASN C 3 311 ? 115.080 152.738 115.677 1.00 69.07  ? 311 ASN A CG  1 
ATOM 4341 O OD1 . ASN C 3 311 ? 115.040 151.571 115.289 1.00 69.07  ? 311 ASN A OD1 1 
ATOM 4342 N ND2 . ASN C 3 311 ? 115.695 153.098 116.798 1.00 69.07  ? 311 ASN A ND2 1 
ATOM 4343 N N   . LYS C 3 312 ? 112.527 151.203 114.390 1.00 73.58  ? 312 LYS A N   1 
ATOM 4344 C CA  . LYS C 3 312 ? 111.497 150.313 114.907 1.00 73.58  ? 312 LYS A CA  1 
ATOM 4345 C C   . LYS C 3 312 ? 111.839 149.689 116.251 1.00 73.58  ? 312 LYS A C   1 
ATOM 4346 O O   . LYS C 3 312 ? 110.921 149.299 116.980 1.00 73.58  ? 312 LYS A O   1 
ATOM 4347 C CB  . LYS C 3 312 ? 111.208 149.189 113.901 1.00 73.58  ? 312 LYS A CB  1 
ATOM 4348 N N   . ARG C 3 313 ? 113.123 149.583 116.598 1.00 73.81  ? 313 ARG A N   1 
ATOM 4349 C CA  . ARG C 3 313 ? 113.496 149.008 117.887 1.00 73.81  ? 313 ARG A CA  1 
ATOM 4350 C C   . ARG C 3 313 ? 113.159 149.961 119.028 1.00 73.81  ? 313 ARG A C   1 
ATOM 4351 O O   . ARG C 3 313 ? 112.358 149.634 119.912 1.00 73.81  ? 313 ARG A O   1 
ATOM 4352 C CB  . ARG C 3 313 ? 114.987 148.661 117.894 1.00 73.81  ? 313 ARG A CB  1 
ATOM 4353 C CG  . ARG C 3 313 ? 115.487 148.030 116.605 1.00 73.81  ? 313 ARG A CG  1 
ATOM 4354 C CD  . ARG C 3 313 ? 115.642 146.525 116.752 1.00 73.81  ? 313 ARG A CD  1 
ATOM 4355 N NE  . ARG C 3 313 ? 116.018 145.888 115.496 1.00 73.81  ? 313 ARG A NE  1 
ATOM 4356 C CZ  . ARG C 3 313 ? 115.155 145.443 114.593 1.00 73.81  ? 313 ARG A CZ  1 
ATOM 4357 N NH1 . ARG C 3 313 ? 113.849 145.553 114.772 1.00 73.81  ? 313 ARG A NH1 1 
ATOM 4358 N NH2 . ARG C 3 313 ? 115.614 144.873 113.482 1.00 73.81  ? 313 ARG A NH2 1 
ATOM 4359 N N   . LYS C 3 314 ? 113.779 151.142 119.031 1.00 74.28  ? 314 LYS A N   1 
ATOM 4360 C CA  . LYS C 3 314 ? 113.543 152.243 119.961 1.00 74.28  ? 314 LYS A CA  1 
ATOM 4361 C C   . LYS C 3 314 ? 113.971 151.929 121.390 1.00 74.28  ? 314 LYS A C   1 
ATOM 4362 O O   . LYS C 3 314 ? 113.878 152.811 122.253 1.00 74.28  ? 314 LYS A O   1 
ATOM 4363 C CB  . LYS C 3 314 ? 112.073 152.691 119.977 1.00 74.28  ? 314 LYS A CB  1 
ATOM 4364 C CG  . LYS C 3 314 ? 111.710 153.674 118.876 1.00 74.28  ? 314 LYS A CG  1 
ATOM 4365 C CD  . LYS C 3 314 ? 112.543 154.941 118.968 1.00 74.28  ? 314 LYS A CD  1 
ATOM 4366 C CE  . LYS C 3 314 ? 112.245 155.881 117.812 1.00 74.28  ? 314 LYS A CE  1 
ATOM 4367 N NZ  . LYS C 3 314 ? 110.795 156.207 117.724 1.00 74.28  ? 314 LYS A NZ  1 
ATOM 4368 N N   . ASP C 3 315 ? 114.437 150.715 121.676 1.00 76.48  ? 315 ASP A N   1 
ATOM 4369 C CA  . ASP C 3 315 ? 114.860 150.341 123.020 1.00 76.48  ? 315 ASP A CA  1 
ATOM 4370 C C   . ASP C 3 315 ? 116.331 149.967 123.088 1.00 76.48  ? 315 ASP A C   1 
ATOM 4371 O O   . ASP C 3 315 ? 117.070 150.522 123.910 1.00 76.48  ? 315 ASP A O   1 
ATOM 4372 C CB  . ASP C 3 315 ? 113.998 149.179 123.538 1.00 76.48  ? 315 ASP A CB  1 
ATOM 4373 N N   . THR C 3 316 ? 116.781 149.036 122.244 1.00 73.92  ? 316 THR A N   1 
ATOM 4374 C CA  . THR C 3 316 ? 118.175 148.609 122.277 1.00 73.92  ? 316 THR A CA  1 
ATOM 4375 C C   . THR C 3 316 ? 119.109 149.641 121.658 1.00 73.92  ? 316 THR A C   1 
ATOM 4376 O O   . THR C 3 316 ? 120.247 149.791 122.116 1.00 73.92  ? 316 THR A O   1 
ATOM 4377 C CB  . THR C 3 316 ? 118.334 147.269 121.556 1.00 73.92  ? 316 THR A CB  1 
ATOM 4378 O OG1 . THR C 3 316 ? 117.950 147.414 120.183 1.00 73.92  ? 316 THR A OG1 1 
ATOM 4379 C CG2 . THR C 3 316 ? 117.464 146.206 122.210 1.00 73.92  ? 316 THR A CG2 1 
ATOM 4380 N N   . LYS C 3 317 ? 118.655 150.354 120.631 1.00 65.72  ? 317 LYS A N   1 
ATOM 4381 C CA  . LYS C 3 317 ? 119.478 151.320 119.922 1.00 65.72  ? 317 LYS A CA  1 
ATOM 4382 C C   . LYS C 3 317 ? 118.839 152.700 119.976 1.00 65.72  ? 317 LYS A C   1 
ATOM 4383 O O   . LYS C 3 317 ? 117.616 152.836 120.073 1.00 65.72  ? 317 LYS A O   1 
ATOM 4384 C CB  . LYS C 3 317 ? 119.689 150.903 118.460 1.00 65.72  ? 317 LYS A CB  1 
ATOM 4385 C CG  . LYS C 3 317 ? 118.429 150.961 117.610 1.00 65.72  ? 317 LYS A CG  1 
ATOM 4386 C CD  . LYS C 3 317 ? 118.758 151.119 116.136 1.00 65.72  ? 317 LYS A CD  1 
ATOM 4387 C CE  . LYS C 3 317 ? 119.832 150.138 115.702 1.00 65.72  ? 317 LYS A CE  1 
ATOM 4388 N NZ  . LYS C 3 317 ? 120.212 150.319 114.275 1.00 65.72  ? 317 LYS A NZ  1 
ATOM 4389 N N   . GLU C 3 318 ? 119.686 153.726 119.921 1.00 59.94  ? 318 GLU A N   1 
ATOM 4390 C CA  . GLU C 3 318 ? 119.246 155.111 119.873 1.00 59.94  ? 318 GLU A CA  1 
ATOM 4391 C C   . GLU C 3 318 ? 119.995 155.835 118.766 1.00 59.94  ? 318 GLU A C   1 
ATOM 4392 O O   . GLU C 3 318 ? 121.172 155.564 118.511 1.00 59.94  ? 318 GLU A O   1 
ATOM 4393 C CB  . GLU C 3 318 ? 119.468 155.825 121.221 1.00 59.94  ? 318 GLU A CB  1 
ATOM 4394 C CG  . GLU C 3 318 ? 118.803 157.208 121.389 1.00 59.94  ? 318 GLU A CG  1 
ATOM 4395 C CD  . GLU C 3 318 ? 117.339 157.304 120.944 1.00 59.94  ? 318 GLU A CD  1 
ATOM 4396 O OE1 . GLU C 3 318 ? 116.689 156.277 120.652 1.00 59.94  ? 318 GLU A OE1 1 
ATOM 4397 O OE2 . GLU C 3 318 ? 116.830 158.443 120.885 1.00 59.94  ? 318 GLU A OE2 1 
ATOM 4398 N N   . ILE C 3 319 ? 119.303 156.761 118.110 1.00 51.91  ? 319 ILE A N   1 
ATOM 4399 C CA  . ILE C 3 319 ? 119.847 157.496 116.974 1.00 51.91  ? 319 ILE A CA  1 
ATOM 4400 C C   . ILE C 3 319 ? 120.272 158.875 117.459 1.00 51.91  ? 319 ILE A C   1 
ATOM 4401 O O   . ILE C 3 319 ? 119.461 159.622 118.019 1.00 51.91  ? 319 ILE A O   1 
ATOM 4402 C CB  . ILE C 3 319 ? 118.824 157.605 115.833 1.00 51.91  ? 319 ILE A CB  1 
ATOM 4403 C CG1 . ILE C 3 319 ? 118.064 156.287 115.658 1.00 51.91  ? 319 ILE A CG1 1 
ATOM 4404 C CG2 . ILE C 3 319 ? 119.512 158.001 114.536 1.00 51.91  ? 319 ILE A CG2 1 
ATOM 4405 C CD1 . ILE C 3 319 ? 118.939 155.111 115.290 1.00 51.91  ? 319 ILE A CD1 1 
ATOM 4406 N N   . TYR C 3 320 ? 121.542 159.214 117.246 1.00 47.57  ? 320 TYR A N   1 
ATOM 4407 C CA  . TYR C 3 320 ? 122.087 160.512 117.629 1.00 47.57  ? 320 TYR A CA  1 
ATOM 4408 C C   . TYR C 3 320 ? 122.067 161.416 116.401 1.00 47.57  ? 320 TYR A C   1 
ATOM 4409 O O   . TYR C 3 320 ? 122.859 161.229 115.475 1.00 47.57  ? 320 TYR A O   1 
ATOM 4410 C CB  . TYR C 3 320 ? 123.505 160.369 118.179 1.00 47.57  ? 320 TYR A CB  1 
ATOM 4411 C CG  . TYR C 3 320 ? 123.616 159.479 119.397 1.00 47.57  ? 320 TYR A CG  1 
ATOM 4412 C CD1 . TYR C 3 320 ? 123.796 158.108 119.266 1.00 47.57  ? 320 TYR A CD1 1 
ATOM 4413 C CD2 . TYR C 3 320 ? 123.548 160.011 120.678 1.00 47.57  ? 320 TYR A CD2 1 
ATOM 4414 C CE1 . TYR C 3 320 ? 123.901 157.292 120.376 1.00 47.57  ? 320 TYR A CE1 1 
ATOM 4415 C CE2 . TYR C 3 320 ? 123.652 159.202 121.794 1.00 47.57  ? 320 TYR A CE2 1 
ATOM 4416 C CZ  . TYR C 3 320 ? 123.829 157.844 121.637 1.00 47.57  ? 320 TYR A CZ  1 
ATOM 4417 O OH  . TYR C 3 320 ? 123.933 157.035 122.745 1.00 47.57  ? 320 TYR A OH  1 
ATOM 4418 N N   . THR C 3 321 ? 121.165 162.393 116.392 1.00 53.24  ? 321 THR A N   1 
ATOM 4419 C CA  . THR C 3 321 ? 120.970 163.265 115.241 1.00 53.24  ? 321 THR A CA  1 
ATOM 4420 C C   . THR C 3 321 ? 121.752 164.559 115.427 1.00 53.24  ? 321 THR A C   1 
ATOM 4421 O O   . THR C 3 321 ? 121.700 165.172 116.498 1.00 53.24  ? 321 THR A O   1 
ATOM 4422 C CB  . THR C 3 321 ? 119.486 163.575 115.035 1.00 53.24  ? 321 THR A CB  1 
ATOM 4423 O OG1 . THR C 3 321 ? 118.989 164.313 116.158 1.00 53.24  ? 321 THR A OG1 1 
ATOM 4424 C CG2 . THR C 3 321 ? 118.689 162.287 114.888 1.00 53.24  ? 321 THR A CG2 1 
ATOM 4425 N N   . HIS C 3 322 ? 122.473 164.968 114.384 1.00 55.18  ? 322 HIS A N   1 
ATOM 4426 C CA  . HIS C 3 322 ? 123.251 166.197 114.413 1.00 55.18  ? 322 HIS A CA  1 
ATOM 4427 C C   . HIS C 3 322 ? 123.152 166.894 113.064 1.00 55.18  ? 322 HIS A C   1 
ATOM 4428 O O   . HIS C 3 322 ? 122.934 166.255 112.030 1.00 55.18  ? 322 HIS A O   1 
ATOM 4429 C CB  . HIS C 3 322 ? 124.722 165.928 114.756 1.00 55.18  ? 322 HIS A CB  1 
ATOM 4430 C CG  . HIS C 3 322 ? 125.483 167.154 115.151 1.00 55.18  ? 322 HIS A CG  1 
ATOM 4431 N ND1 . HIS C 3 322 ? 126.585 167.603 114.455 1.00 55.18  ? 322 HIS A ND1 1 
ATOM 4432 C CD2 . HIS C 3 322 ? 125.302 168.027 116.170 1.00 55.18  ? 322 HIS A CD2 1 
ATOM 4433 C CE1 . HIS C 3 322 ? 127.049 168.699 115.028 1.00 55.18  ? 322 HIS A CE1 1 
ATOM 4434 N NE2 . HIS C 3 322 ? 126.289 168.977 116.071 1.00 55.18  ? 322 HIS A NE2 1 
ATOM 4435 N N   . PHE C 3 323 ? 123.316 168.213 113.090 1.00 60.76  ? 323 PHE A N   1 
ATOM 4436 C CA  . PHE C 3 323 ? 123.278 169.049 111.898 1.00 60.76  ? 323 PHE A CA  1 
ATOM 4437 C C   . PHE C 3 323 ? 124.686 169.525 111.573 1.00 60.76  ? 323 PHE A C   1 
ATOM 4438 O O   . PHE C 3 323 ? 125.388 170.041 112.449 1.00 60.76  ? 323 PHE A O   1 
ATOM 4439 C CB  . PHE C 3 323 ? 122.350 170.249 112.101 1.00 60.76  ? 323 PHE A CB  1 
ATOM 4440 C CG  . PHE C 3 323 ? 120.891 169.914 111.992 1.00 60.76  ? 323 PHE A CG  1 
ATOM 4441 C CD1 . PHE C 3 323 ? 120.241 169.981 110.771 1.00 60.76  ? 323 PHE A CD1 1 
ATOM 4442 C CD2 . PHE C 3 323 ? 120.170 169.530 113.110 1.00 60.76  ? 323 PHE A CD2 1 
ATOM 4443 C CE1 . PHE C 3 323 ? 118.898 169.675 110.669 1.00 60.76  ? 323 PHE A CE1 1 
ATOM 4444 C CE2 . PHE C 3 323 ? 118.827 169.221 113.013 1.00 60.76  ? 323 PHE A CE2 1 
ATOM 4445 C CZ  . PHE C 3 323 ? 118.191 169.293 111.791 1.00 60.76  ? 323 PHE A CZ  1 
ATOM 4446 N N   . THR C 3 324 ? 125.094 169.350 110.321 1.00 60.75  ? 324 THR A N   1 
ATOM 4447 C CA  . THR C 3 324 ? 126.418 169.778 109.885 1.00 60.75  ? 324 THR A CA  1 
ATOM 4448 C C   . THR C 3 324 ? 126.351 171.122 109.169 1.00 60.75  ? 324 THR A C   1 
ATOM 4449 O O   . THR C 3 324 ? 127.128 172.031 109.462 1.00 60.75  ? 324 THR A O   1 
ATOM 4450 C CB  . THR C 3 324 ? 127.069 168.743 108.952 1.00 60.75  ? 324 THR A CB  1 
ATOM 4451 O OG1 . THR C 3 324 ? 126.861 167.425 109.476 1.00 60.75  ? 324 THR A OG1 1 
ATOM 4452 C CG2 . THR C 3 324 ? 128.562 169.004 108.824 1.00 60.75  ? 324 THR A CG2 1 
ATOM 4453 N N   . THR C 3 329 ? 134.600 171.926 114.928 1.00 60.75  ? 329 THR A N   1 
ATOM 4454 C CA  . THR C 3 329 ? 134.906 170.689 115.637 1.00 60.75  ? 329 THR A CA  1 
ATOM 4455 C C   . THR C 3 329 ? 133.675 170.146 116.354 1.00 60.75  ? 329 THR A C   1 
ATOM 4456 O O   . THR C 3 329 ? 133.789 169.402 117.328 1.00 60.75  ? 329 THR A O   1 
ATOM 4457 C CB  . THR C 3 329 ? 136.039 170.891 116.661 1.00 60.75  ? 329 THR A CB  1 
ATOM 4458 O OG1 . THR C 3 329 ? 135.597 171.777 117.697 1.00 60.75  ? 329 THR A OG1 1 
ATOM 4459 C CG2 . THR C 3 329 ? 137.269 171.478 115.987 1.00 60.75  ? 329 THR A CG2 1 
ATOM 4460 N N   . LYS C 3 330 ? 132.492 170.534 115.873 1.00 57.24  ? 330 LYS A N   1 
ATOM 4461 C CA  . LYS C 3 330 ? 131.257 170.029 116.464 1.00 57.24  ? 330 LYS A CA  1 
ATOM 4462 C C   . LYS C 3 330 ? 131.031 168.564 116.106 1.00 57.24  ? 330 LYS A C   1 
ATOM 4463 O O   . LYS C 3 330 ? 130.539 167.787 116.934 1.00 57.24  ? 330 LYS A O   1 
ATOM 4464 C CB  . LYS C 3 330 ? 130.072 170.886 116.018 1.00 57.24  ? 330 LYS A CB  1 
ATOM 4465 C CG  . LYS C 3 330 ? 129.911 171.000 114.510 1.00 57.24  ? 330 LYS A CG  1 
ATOM 4466 C CD  . LYS C 3 330 ? 128.759 171.918 114.141 1.00 57.24  ? 330 LYS A CD  1 
ATOM 4467 C CE  . LYS C 3 330 ? 128.605 172.025 112.632 1.00 57.24  ? 330 LYS A CE  1 
ATOM 4468 N NZ  . LYS C 3 330 ? 127.485 172.929 112.249 1.00 57.24  ? 330 LYS A NZ  1 
ATOM 4469 N N   . ASN C 3 331 ? 131.384 168.170 114.880 1.00 56.37  ? 331 ASN A N   1 
ATOM 4470 C CA  . ASN C 3 331 ? 131.151 166.798 114.441 1.00 56.37  ? 331 ASN A CA  1 
ATOM 4471 C C   . ASN C 3 331 ? 131.980 165.809 115.250 1.00 56.37  ? 331 ASN A C   1 
ATOM 4472 O O   . ASN C 3 331 ? 131.473 164.768 115.687 1.00 56.37  ? 331 ASN A O   1 
ATOM 4473 C CB  . ASN C 3 331 ? 131.463 166.666 112.950 1.00 56.37  ? 331 ASN A CB  1 
ATOM 4474 C CG  . ASN C 3 331 ? 130.536 167.496 112.084 1.00 56.37  ? 331 ASN A CG  1 
ATOM 4475 O OD1 . ASN C 3 331 ? 130.873 167.846 110.953 1.00 56.37  ? 331 ASN A OD1 1 
ATOM 4476 N ND2 . ASN C 3 331 ? 129.361 167.817 112.612 1.00 56.37  ? 331 ASN A ND2 1 
ATOM 4477 N N   . VAL C 3 332 ? 133.261 166.118 115.466 1.00 56.33  ? 332 VAL A N   1 
ATOM 4478 C CA  . VAL C 3 332 ? 134.129 165.198 116.193 1.00 56.33  ? 332 VAL A CA  1 
ATOM 4479 C C   . VAL C 3 332 ? 133.712 165.109 117.656 1.00 56.33  ? 332 VAL A C   1 
ATOM 4480 O O   . VAL C 3 332 ? 133.743 164.029 118.256 1.00 56.33  ? 332 VAL A O   1 
ATOM 4481 C CB  . VAL C 3 332 ? 135.604 165.612 116.037 1.00 56.33  ? 332 VAL A CB  1 
ATOM 4482 C CG1 . VAL C 3 332 ? 136.079 165.339 114.619 1.00 56.33  ? 332 VAL A CG1 1 
ATOM 4483 C CG2 . VAL C 3 332 ? 135.793 167.079 116.385 1.00 56.33  ? 332 VAL A CG2 1 
ATOM 4484 N N   . GLN C 3 333 ? 133.307 166.234 118.251 1.00 52.87  ? 333 GLN A N   1 
ATOM 4485 C CA  . GLN C 3 333 ? 132.823 166.207 119.628 1.00 52.87  ? 333 GLN A CA  1 
ATOM 4486 C C   . GLN C 3 333 ? 131.540 165.392 119.749 1.00 52.87  ? 333 GLN A C   1 
ATOM 4487 O O   . GLN C 3 333 ? 131.377 164.616 120.699 1.00 52.87  ? 333 GLN A O   1 
ATOM 4488 C CB  . GLN C 3 333 ? 132.604 167.632 120.135 1.00 52.87  ? 333 GLN A CB  1 
ATOM 4489 C CG  . GLN C 3 333 ? 132.169 167.715 121.589 1.00 52.87  ? 333 GLN A CG  1 
ATOM 4490 C CD  . GLN C 3 333 ? 133.244 167.246 122.550 1.00 52.87  ? 333 GLN A CD  1 
ATOM 4491 O OE1 . GLN C 3 333 ? 134.424 167.548 122.375 1.00 52.87  ? 333 GLN A OE1 1 
ATOM 4492 N NE2 . GLN C 3 333 ? 132.838 166.505 123.574 1.00 52.87  ? 333 GLN A NE2 1 
ATOM 4493 N N   . PHE C 3 334 ? 130.620 165.555 118.795 1.00 48.83  ? 334 PHE A N   1 
ATOM 4494 C CA  . PHE C 3 334 ? 129.387 164.775 118.812 1.00 48.83  ? 334 PHE A CA  1 
ATOM 4495 C C   . PHE C 3 334 ? 129.677 163.286 118.672 1.00 48.83  ? 334 PHE A C   1 
ATOM 4496 O O   . PHE C 3 334 ? 129.090 162.459 119.381 1.00 48.83  ? 334 PHE A O   1 
ATOM 4497 C CB  . PHE C 3 334 ? 128.457 165.251 117.696 1.00 48.83  ? 334 PHE A CB  1 
ATOM 4498 C CG  . PHE C 3 334 ? 127.053 164.732 117.812 1.00 48.83  ? 334 PHE A CG  1 
ATOM 4499 C CD1 . PHE C 3 334 ? 126.178 165.264 118.744 1.00 48.83  ? 334 PHE A CD1 1 
ATOM 4500 C CD2 . PHE C 3 334 ? 126.606 163.716 116.984 1.00 48.83  ? 334 PHE A CD2 1 
ATOM 4501 C CE1 . PHE C 3 334 ? 124.885 164.791 118.850 1.00 48.83  ? 334 PHE A CE1 1 
ATOM 4502 C CE2 . PHE C 3 334 ? 125.315 163.238 117.086 1.00 48.83  ? 334 PHE A CE2 1 
ATOM 4503 C CZ  . PHE C 3 334 ? 124.453 163.777 118.020 1.00 48.83  ? 334 PHE A CZ  1 
ATOM 4504 N N   . VAL C 3 335 ? 130.590 162.929 117.765 1.00 46.43  ? 335 VAL A N   1 
ATOM 4505 C CA  . VAL C 3 335 ? 130.954 161.527 117.581 1.00 46.43  ? 335 VAL A CA  1 
ATOM 4506 C C   . VAL C 3 335 ? 131.595 160.970 118.846 1.00 46.43  ? 335 VAL A C   1 
ATOM 4507 O O   . VAL C 3 335 ? 131.308 159.840 119.258 1.00 46.43  ? 335 VAL A O   1 
ATOM 4508 C CB  . VAL C 3 335 ? 131.877 161.373 116.357 1.00 46.43  ? 335 VAL A CB  1 
ATOM 4509 C CG1 . VAL C 3 335 ? 132.526 160.000 116.346 1.00 46.43  ? 335 VAL A CG1 1 
ATOM 4510 C CG2 . VAL C 3 335 ? 131.094 161.602 115.075 1.00 46.43  ? 335 VAL A CG2 1 
ATOM 4511 N N   . PHE C 3 336 ? 132.476 161.750 119.479 1.00 47.95  ? 336 PHE A N   1 
ATOM 4512 C CA  . PHE C 3 336 ? 133.123 161.297 120.705 1.00 47.95  ? 336 PHE A CA  1 
ATOM 4513 C C   . PHE C 3 336 ? 132.105 161.075 121.817 1.00 47.95  ? 336 PHE A C   1 
ATOM 4514 O O   . PHE C 3 336 ? 132.170 160.071 122.536 1.00 47.95  ? 336 PHE A O   1 
ATOM 4515 C CB  . PHE C 3 336 ? 134.184 162.307 121.140 1.00 47.95  ? 336 PHE A CB  1 
ATOM 4516 C CG  . PHE C 3 336 ? 134.900 161.929 122.404 1.00 47.95  ? 336 PHE A CG  1 
ATOM 4517 C CD1 . PHE C 3 336 ? 135.465 160.673 122.547 1.00 47.95  ? 336 PHE A CD1 1 
ATOM 4518 C CD2 . PHE C 3 336 ? 135.010 162.830 123.450 1.00 47.95  ? 336 PHE A CD2 1 
ATOM 4519 C CE1 . PHE C 3 336 ? 136.126 160.322 123.709 1.00 47.95  ? 336 PHE A CE1 1 
ATOM 4520 C CE2 . PHE C 3 336 ? 135.670 162.486 124.614 1.00 47.95  ? 336 PHE A CE2 1 
ATOM 4521 C CZ  . PHE C 3 336 ? 136.228 161.230 124.744 1.00 47.95  ? 336 PHE A CZ  1 
ATOM 4522 N N   . ASP C 3 337 ? 131.151 161.997 121.970 1.00 45.03  ? 337 ASP A N   1 
ATOM 4523 C CA  . ASP C 3 337 ? 130.117 161.820 122.986 1.00 45.03  ? 337 ASP A CA  1 
ATOM 4524 C C   . ASP C 3 337 ? 129.270 160.586 122.702 1.00 45.03  ? 337 ASP A C   1 
ATOM 4525 O O   . ASP C 3 337 ? 128.961 159.807 123.615 1.00 45.03  ? 337 ASP A O   1 
ATOM 4526 C CB  . ASP C 3 337 ? 129.238 163.068 123.063 1.00 45.03  ? 337 ASP A CB  1 
ATOM 4527 C CG  . ASP C 3 337 ? 129.675 164.023 124.156 1.00 45.03  ? 337 ASP A CG  1 
ATOM 4528 O OD1 . ASP C 3 337 ? 130.746 163.792 124.757 1.00 45.03  ? 337 ASP A OD1 1 
ATOM 4529 O OD2 . ASP C 3 337 ? 128.946 165.003 124.417 1.00 45.03  ? 337 ASP A OD2 1 
ATOM 4530 N N   . ALA C 3 338 ? 128.890 160.385 121.436 1.00 40.72  ? 338 ALA A N   1 
ATOM 4531 C CA  . ALA C 3 338 ? 128.072 159.230 121.086 1.00 40.72  ? 338 ALA A CA  1 
ATOM 4532 C C   . ALA C 3 338 ? 128.808 157.924 121.356 1.00 40.72  ? 338 ALA A C   1 
ATOM 4533 O O   . ALA C 3 338 ? 128.233 156.985 121.921 1.00 40.72  ? 338 ALA A O   1 
ATOM 4534 C CB  . ALA C 3 338 ? 127.645 159.315 119.621 1.00 40.72  ? 338 ALA A CB  1 
ATOM 4535 N N   . VAL C 3 339 ? 130.085 157.845 120.971 1.00 40.14  ? 339 VAL A N   1 
ATOM 4536 C CA  . VAL C 3 339 ? 130.824 156.605 121.185 1.00 40.14  ? 339 VAL A CA  1 
ATOM 4537 C C   . VAL C 3 339 ? 131.100 156.387 122.667 1.00 40.14  ? 339 VAL A C   1 
ATOM 4538 O O   . VAL C 3 339 ? 131.140 155.243 123.128 1.00 40.14  ? 339 VAL A O   1 
ATOM 4539 C CB  . VAL C 3 339 ? 132.123 156.575 120.353 1.00 40.14  ? 339 VAL A CB  1 
ATOM 4540 C CG1 . VAL C 3 339 ? 131.810 156.730 118.872 1.00 40.14  ? 339 VAL A CG1 1 
ATOM 4541 C CG2 . VAL C 3 339 ? 133.100 157.636 120.820 1.00 40.14  ? 339 VAL A CG2 1 
ATOM 4542 N N   . THR C 3 340 ? 131.281 157.462 123.442 1.00 37.64  ? 340 THR A N   1 
ATOM 4543 C CA  . THR C 3 340 ? 131.431 157.302 124.884 1.00 37.64  ? 340 THR A CA  1 
ATOM 4544 C C   . THR C 3 340 ? 130.159 156.740 125.507 1.00 37.64  ? 340 THR A C   1 
ATOM 4545 O O   . THR C 3 340 ? 130.217 155.843 126.357 1.00 37.64  ? 340 THR A O   1 
ATOM 4546 C CB  . THR C 3 340 ? 131.798 158.639 125.528 1.00 37.64  ? 340 THR A CB  1 
ATOM 4547 O OG1 . THR C 3 340 ? 133.005 159.139 124.940 1.00 37.64  ? 340 THR A OG1 1 
ATOM 4548 C CG2 . THR C 3 340 ? 132.004 158.472 127.026 1.00 37.64  ? 340 THR A CG2 1 
ATOM 4549 N N   . ASP C 3 341 ? 128.997 157.248 125.085 1.00 40.65  ? 341 ASP A N   1 
ATOM 4550 C CA  . ASP C 3 341 ? 127.735 156.714 125.587 1.00 40.65  ? 341 ASP A CA  1 
ATOM 4551 C C   . ASP C 3 341 ? 127.560 155.251 125.193 1.00 40.65  ? 341 ASP A C   1 
ATOM 4552 O O   . ASP C 3 341 ? 127.111 154.428 126.003 1.00 40.65  ? 341 ASP A O   1 
ATOM 4553 C CB  . ASP C 3 341 ? 126.568 157.554 125.068 1.00 40.65  ? 341 ASP A CB  1 
ATOM 4554 C CG  . ASP C 3 341 ? 125.354 157.490 125.975 1.00 40.65  ? 341 ASP A CG  1 
ATOM 4555 O OD1 . ASP C 3 341 ? 124.891 156.370 126.276 1.00 40.65  ? 341 ASP A OD1 1 
ATOM 4556 O OD2 . ASP C 3 341 ? 124.862 158.562 126.387 1.00 40.65  ? 341 ASP A OD2 1 
ATOM 4557 N N   . VAL C 3 342 ? 127.914 154.909 123.951 1.00 37.65  ? 342 VAL A N   1 
ATOM 4558 C CA  . VAL C 3 342 ? 127.798 153.526 123.495 1.00 37.65  ? 342 VAL A CA  1 
ATOM 4559 C C   . VAL C 3 342 ? 128.717 152.618 124.302 1.00 37.65  ? 342 VAL A C   1 
ATOM 4560 O O   . VAL C 3 342 ? 128.334 151.507 124.687 1.00 37.65  ? 342 VAL A O   1 
ATOM 4561 C CB  . VAL C 3 342 ? 128.091 153.433 121.986 1.00 37.65  ? 342 VAL A CB  1 
ATOM 4562 C CG1 . VAL C 3 342 ? 128.173 151.979 121.547 1.00 37.65  ? 342 VAL A CG1 1 
ATOM 4563 C CG2 . VAL C 3 342 ? 127.023 154.163 121.201 1.00 37.65  ? 342 VAL A CG2 1 
ATOM 4564 N N   . ILE C 3 343 ? 129.948 153.069 124.558 1.00 33.05  ? 343 ILE A N   1 
ATOM 4565 C CA  . ILE C 3 343 ? 130.886 152.279 125.349 1.00 33.05  ? 343 ILE A CA  1 
ATOM 4566 C C   . ILE C 3 343 ? 130.348 152.069 126.756 1.00 33.05  ? 343 ILE A C   1 
ATOM 4567 O O   . ILE C 3 343 ? 130.386 150.954 127.289 1.00 33.05  ? 343 ILE A O   1 
ATOM 4568 C CB  . ILE C 3 343 ? 132.272 152.952 125.365 1.00 33.05  ? 343 ILE A CB  1 
ATOM 4569 C CG1 . ILE C 3 343 ? 132.988 152.734 124.032 1.00 33.05  ? 343 ILE A CG1 1 
ATOM 4570 C CG2 . ILE C 3 343 ? 133.115 152.424 126.517 1.00 33.05  ? 343 ILE A CG2 1 
ATOM 4571 C CD1 . ILE C 3 343 ? 134.064 153.757 123.744 1.00 33.05  ? 343 ILE A CD1 1 
ATOM 4572 N N   . ILE C 3 344 ? 129.827 153.132 127.375 1.00 31.20  ? 344 ILE A N   1 
ATOM 4573 C CA  . ILE C 3 344 ? 129.255 153.007 128.714 1.00 31.20  ? 344 ILE A CA  1 
ATOM 4574 C C   . ILE C 3 344 ? 128.138 151.972 128.722 1.00 31.20  ? 344 ILE A C   1 
ATOM 4575 O O   . ILE C 3 344 ? 128.122 151.061 129.556 1.00 31.20  ? 344 ILE A O   1 
ATOM 4576 C CB  . ILE C 3 344 ? 128.758 154.373 129.222 1.00 31.20  ? 344 ILE A CB  1 
ATOM 4577 C CG1 . ILE C 3 344 ? 129.939 155.288 129.535 1.00 31.20  ? 344 ILE A CG1 1 
ATOM 4578 C CG2 . ILE C 3 344 ? 127.882 154.198 130.453 1.00 31.20  ? 344 ILE A CG2 1 
ATOM 4579 C CD1 . ILE C 3 344 ? 130.791 154.785 130.676 1.00 31.20  ? 344 ILE A CD1 1 
ATOM 4580 N N   . LYS C 3 345 ? 127.201 152.084 127.778 1.00 32.55  ? 345 LYS A N   1 
ATOM 4581 C CA  . LYS C 3 345 ? 126.058 151.175 127.763 1.00 32.55  ? 345 LYS A CA  1 
ATOM 4582 C C   . LYS C 3 345 ? 126.498 149.732 127.534 1.00 32.55  ? 345 LYS A C   1 
ATOM 4583 O O   . LYS C 3 345 ? 126.094 148.822 128.269 1.00 32.55  ? 345 LYS A O   1 
ATOM 4584 C CB  . LYS C 3 345 ? 125.058 151.610 126.692 1.00 32.55  ? 345 LYS A CB  1 
ATOM 4585 N N   . ASN C 3 346 ? 127.346 149.507 126.527 1.00 36.85  ? 346 ASN A N   1 
ATOM 4586 C CA  . ASN C 3 346 ? 127.751 148.147 126.186 1.00 36.85  ? 346 ASN A CA  1 
ATOM 4587 C C   . ASN C 3 346 ? 128.576 147.513 127.298 1.00 36.85  ? 346 ASN A C   1 
ATOM 4588 O O   . ASN C 3 346 ? 128.416 146.322 127.592 1.00 36.85  ? 346 ASN A O   1 
ATOM 4589 C CB  . ASN C 3 346 ? 128.533 148.149 124.873 1.00 36.85  ? 346 ASN A CB  1 
ATOM 4590 N N   . ASN C 3 347 ? 129.464 148.286 127.927 1.00 35.12  ? 347 ASN A N   1 
ATOM 4591 C CA  . ASN C 3 347 ? 130.324 147.732 128.963 1.00 35.12  ? 347 ASN A CA  1 
ATOM 4592 C C   . ASN C 3 347 ? 129.548 147.528 130.262 1.00 35.12  ? 347 ASN A C   1 
ATOM 4593 O O   . ASN C 3 347 ? 129.834 146.588 131.013 1.00 35.12  ? 347 ASN A O   1 
ATOM 4594 C CB  . ASN C 3 347 ? 131.539 148.657 129.127 1.00 35.12  ? 347 ASN A CB  1 
ATOM 4595 C CG  . ASN C 3 347 ? 132.352 148.388 130.382 1.00 35.12  ? 347 ASN A CG  1 
ATOM 4596 O OD1 . ASN C 3 347 ? 132.346 147.290 130.936 1.00 35.12  ? 347 ASN A OD1 1 
ATOM 4597 N ND2 . ASN C 3 347 ? 133.094 149.400 130.814 1.00 35.12  ? 347 ASN A ND2 1 
ATOM 4598 N N   . LEU C 3 348 ? 128.538 148.364 130.525 1.00 36.75  ? 348 LEU A N   1 
ATOM 4599 C CA  . LEU C 3 348 ? 127.669 148.137 131.674 1.00 36.75  ? 348 LEU A CA  1 
ATOM 4600 C C   . LEU C 3 348 ? 126.750 146.944 131.456 1.00 36.75  ? 348 LEU A C   1 
ATOM 4601 O O   . LEU C 3 348 ? 126.327 146.304 132.426 1.00 36.75  ? 348 LEU A O   1 
ATOM 4602 C CB  . LEU C 3 348 ? 126.840 149.388 131.961 1.00 36.75  ? 348 LEU A CB  1 
ATOM 4603 C CG  . LEU C 3 348 ? 127.496 150.465 132.822 1.00 36.75  ? 348 LEU A CG  1 
ATOM 4604 C CD1 . LEU C 3 348 ? 126.459 151.480 133.272 1.00 36.75  ? 348 LEU A CD1 1 
ATOM 4605 C CD2 . LEU C 3 348 ? 128.192 149.834 134.012 1.00 36.75  ? 348 LEU A CD2 1 
ATOM 4606 N N   . LYS C 3 349 ? 126.420 146.638 130.198 1.00 44.68  ? 349 LYS A N   1 
ATOM 4607 C CA  . LYS C 3 349 ? 125.567 145.486 129.922 1.00 44.68  ? 349 LYS A CA  1 
ATOM 4608 C C   . LYS C 3 349 ? 126.230 144.177 130.335 1.00 44.68  ? 349 LYS A C   1 
ATOM 4609 O O   . LYS C 3 349 ? 125.548 143.156 130.477 1.00 44.68  ? 349 LYS A O   1 
ATOM 4610 C CB  . LYS C 3 349 ? 125.199 145.448 128.438 1.00 44.68  ? 349 LYS A CB  1 
ATOM 4611 N N   . ASP C 3 350 ? 127.548 144.181 130.530 1.00 47.48  ? 350 ASP A N   1 
ATOM 4612 C CA  . ASP C 3 350 ? 128.278 142.980 130.917 1.00 47.48  ? 350 ASP A CA  1 
ATOM 4613 C C   . ASP C 3 350 ? 128.891 143.082 132.304 1.00 47.48  ? 350 ASP A C   1 
ATOM 4614 O O   . ASP C 3 350 ? 128.678 142.192 133.136 1.00 47.48  ? 350 ASP A O   1 
ATOM 4615 C CB  . ASP C 3 350 ? 129.374 142.673 129.884 1.00 47.48  ? 350 ASP A CB  1 
ATOM 4616 C CG  . ASP C 3 350 ? 128.810 142.231 128.548 1.00 47.48  ? 350 ASP A CG  1 
ATOM 4617 O OD1 . ASP C 3 350 ? 127.711 141.639 128.531 1.00 47.48  ? 350 ASP A OD1 1 
ATOM 4618 O OD2 . ASP C 3 350 ? 129.469 142.472 127.515 1.00 47.48  ? 350 ASP A OD2 1 
ATOM 4619 N N   . CYS C 3 351 ? 129.650 144.142 132.584 1.00 44.63  ? 351 CYS A N   1 
ATOM 4620 C CA  . CYS C 3 351 ? 130.396 144.258 133.829 1.00 44.63  ? 351 CYS A CA  1 
ATOM 4621 C C   . CYS C 3 351 ? 129.801 145.276 134.793 1.00 44.63  ? 351 CYS A C   1 
ATOM 4622 O O   . CYS C 3 351 ? 130.524 145.794 135.650 1.00 44.63  ? 351 CYS A O   1 
ATOM 4623 C CB  . CYS C 3 351 ? 131.854 144.618 133.534 1.00 44.63  ? 351 CYS A CB  1 
ATOM 4624 S SG  . CYS C 3 351 ? 132.773 143.342 132.648 1.00 44.63  ? 351 CYS A SG  1 
ATOM 4625 N N   . GLY C 3 352 ? 128.508 145.572 134.680 1.00 38.47  ? 352 GLY A N   1 
ATOM 4626 C CA  . GLY C 3 352 ? 127.895 146.596 135.505 1.00 38.47  ? 352 GLY A CA  1 
ATOM 4627 C C   . GLY C 3 352 ? 127.965 146.325 136.994 1.00 38.47  ? 352 GLY A C   1 
ATOM 4628 O O   . GLY C 3 352 ? 128.700 147.006 137.716 1.00 38.47  ? 352 GLY A O   1 
ATOM 4629 N N   . LEU C 3 353 ? 127.215 145.326 137.457 1.00 39.20  ? 353 LEU A N   1 
ATOM 4630 C CA  . LEU C 3 353 ? 127.189 144.923 138.864 1.00 39.20  ? 353 LEU A CA  1 
ATOM 4631 C C   . LEU C 3 353 ? 126.905 146.118 139.776 1.00 39.20  ? 353 LEU A C   1 
ATOM 4632 O O   . LEU C 3 353 ? 127.726 146.517 140.604 1.00 39.20  ? 353 LEU A O   1 
ATOM 4633 C CB  . LEU C 3 353 ? 128.494 144.225 139.259 1.00 39.20  ? 353 LEU A CB  1 
ATOM 4634 C CG  . LEU C 3 353 ? 128.590 142.716 139.015 1.00 39.20  ? 353 LEU A CG  1 
ATOM 4635 C CD1 . LEU C 3 353 ? 127.531 141.983 139.824 1.00 39.20  ? 353 LEU A CD1 1 
ATOM 4636 C CD2 . LEU C 3 353 ? 128.483 142.366 137.535 1.00 39.20  ? 353 LEU A CD2 1 
ATOM 4637 N N   . PHE C 3 354 ? 125.718 146.691 139.601 1.00 41.10  ? 354 PHE A N   1 
ATOM 4638 C CA  . PHE C 3 354 ? 125.293 147.835 140.400 1.00 41.10  ? 354 PHE A CA  1 
ATOM 4639 C C   . PHE C 3 354 ? 125.184 147.469 141.877 1.00 41.10  ? 354 PHE A C   1 
ATOM 4640 O O   . PHE C 3 354 ? 126.083 147.759 142.666 1.00 41.10  ? 354 PHE A O   1 
ATOM 4641 C CB  . PHE C 3 354 ? 123.953 148.377 139.896 1.00 41.10  ? 354 PHE A CB  1 
ATOM 4642 C CG  . PHE C 3 354 ? 124.038 149.066 138.564 1.00 41.10  ? 354 PHE A CG  1 
ATOM 4643 C CD1 . PHE C 3 354 ? 125.241 149.579 138.108 1.00 41.10  ? 354 PHE A CD1 1 
ATOM 4644 C CD2 . PHE C 3 354 ? 122.912 149.205 137.769 1.00 41.10  ? 354 PHE A CD2 1 
ATOM 4645 C CE1 . PHE C 3 354 ? 125.320 150.214 136.883 1.00 41.10  ? 354 PHE A CE1 1 
ATOM 4646 C CE2 . PHE C 3 354 ? 122.985 149.840 136.545 1.00 41.10  ? 354 PHE A CE2 1 
ATOM 4647 C CZ  . PHE C 3 354 ? 124.190 150.345 136.101 1.00 41.10  ? 354 PHE A CZ  1 
ATOM 4648 N N   . LEU D 4 7   ? 117.086 138.523 70.027  1.00 117.20 ? 7   LEU B N   1 
ATOM 4649 C CA  . LEU D 4 7   ? 116.431 137.258 69.717  1.00 117.20 ? 7   LEU B CA  1 
ATOM 4650 C C   . LEU D 4 7   ? 115.900 136.592 70.982  1.00 117.20 ? 7   LEU B C   1 
ATOM 4651 O O   . LEU D 4 7   ? 116.356 135.514 71.365  1.00 117.20 ? 7   LEU B O   1 
ATOM 4652 C CB  . LEU D 4 7   ? 117.397 136.317 68.992  1.00 117.20 ? 7   LEU B CB  1 
ATOM 4653 N N   . ARG D 4 8   ? 114.935 137.248 71.631  1.00 119.36 ? 8   ARG B N   1 
ATOM 4654 C CA  . ARG D 4 8   ? 114.348 136.690 72.845  1.00 119.36 ? 8   ARG B CA  1 
ATOM 4655 C C   . ARG D 4 8   ? 113.605 135.392 72.555  1.00 119.36 ? 8   ARG B C   1 
ATOM 4656 O O   . ARG D 4 8   ? 113.691 134.432 73.331  1.00 119.36 ? 8   ARG B O   1 
ATOM 4657 C CB  . ARG D 4 8   ? 113.412 137.712 73.493  1.00 119.36 ? 8   ARG B CB  1 
ATOM 4658 N N   . GLN D 4 9   ? 112.864 135.346 71.445  1.00 118.16 ? 9   GLN B N   1 
ATOM 4659 C CA  . GLN D 4 9   ? 112.145 134.128 71.085  1.00 118.16 ? 9   GLN B CA  1 
ATOM 4660 C C   . GLN D 4 9   ? 113.107 132.981 70.803  1.00 118.16 ? 9   GLN B C   1 
ATOM 4661 O O   . GLN D 4 9   ? 112.869 131.843 71.225  1.00 118.16 ? 9   GLN B O   1 
ATOM 4662 C CB  . GLN D 4 9   ? 111.247 134.387 69.875  1.00 118.16 ? 9   GLN B CB  1 
ATOM 4663 N N   . GLU D 4 10  ? 114.198 133.260 70.085  1.00 120.14 ? 10  GLU B N   1 
ATOM 4664 C CA  . GLU D 4 10  ? 115.188 132.224 69.808  1.00 120.14 ? 10  GLU B CA  1 
ATOM 4665 C C   . GLU D 4 10  ? 115.840 131.729 71.093  1.00 120.14 ? 10  GLU B C   1 
ATOM 4666 O O   . GLU D 4 10  ? 116.063 130.524 71.260  1.00 120.14 ? 10  GLU B O   1 
ATOM 4667 C CB  . GLU D 4 10  ? 116.244 132.752 68.837  1.00 120.14 ? 10  GLU B CB  1 
ATOM 4668 N N   . ALA D 4 11  ? 116.157 132.646 72.011  1.00 117.62 ? 11  ALA B N   1 
ATOM 4669 C CA  . ALA D 4 11  ? 116.743 132.245 73.286  1.00 117.62 ? 11  ALA B CA  1 
ATOM 4670 C C   . ALA D 4 11  ? 115.779 131.382 74.090  1.00 117.62 ? 11  ALA B C   1 
ATOM 4671 O O   . ALA D 4 11  ? 116.184 130.380 74.690  1.00 117.62 ? 11  ALA B O   1 
ATOM 4672 C CB  . ALA D 4 11  ? 117.154 133.480 74.087  1.00 117.62 ? 11  ALA B CB  1 
ATOM 4673 N N   . GLU D 4 12  ? 114.497 131.758 74.114  1.00 117.93 ? 12  GLU B N   1 
ATOM 4674 C CA  . GLU D 4 12  ? 113.507 130.962 74.833  1.00 117.93 ? 12  GLU B CA  1 
ATOM 4675 C C   . GLU D 4 12  ? 113.354 129.579 74.213  1.00 117.93 ? 12  GLU B C   1 
ATOM 4676 O O   . GLU D 4 12  ? 113.246 128.577 74.930  1.00 117.93 ? 12  GLU B O   1 
ATOM 4677 C CB  . GLU D 4 12  ? 112.164 131.693 74.857  1.00 117.93 ? 12  GLU B CB  1 
ATOM 4678 N N   . GLN D 4 13  ? 113.340 129.505 72.879  1.00 119.67 ? 13  GLN B N   1 
ATOM 4679 C CA  . GLN D 4 13  ? 113.241 128.211 72.211  1.00 119.67 ? 13  GLN B CA  1 
ATOM 4680 C C   . GLN D 4 13  ? 114.454 127.339 72.512  1.00 119.67 ? 13  GLN B C   1 
ATOM 4681 O O   . GLN D 4 13  ? 114.317 126.135 72.759  1.00 119.67 ? 13  GLN B O   1 
ATOM 4682 C CB  . GLN D 4 13  ? 113.082 128.410 70.703  1.00 119.67 ? 13  GLN B CB  1 
ATOM 4683 N N   . LEU D 4 14  ? 115.652 127.930 72.493  1.00 117.25 ? 14  LEU B N   1 
ATOM 4684 C CA  . LEU D 4 14  ? 116.857 127.171 72.809  1.00 117.25 ? 14  LEU B CA  1 
ATOM 4685 C C   . LEU D 4 14  ? 116.837 126.680 74.251  1.00 117.25 ? 14  LEU B C   1 
ATOM 4686 O O   . LEU D 4 14  ? 117.223 125.539 74.531  1.00 117.25 ? 14  LEU B O   1 
ATOM 4687 C CB  . LEU D 4 14  ? 118.099 128.023 72.547  1.00 117.25 ? 14  LEU B CB  1 
ATOM 4688 C CG  . LEU D 4 14  ? 118.702 127.924 71.145  1.00 117.25 ? 14  LEU B CG  1 
ATOM 4689 C CD1 . LEU D 4 14  ? 119.693 129.052 70.905  1.00 117.25 ? 14  LEU B CD1 1 
ATOM 4690 C CD2 . LEU D 4 14  ? 119.364 126.570 70.939  1.00 117.25 ? 14  LEU B CD2 1 
ATOM 4691 N N   . LYS D 4 15  ? 116.392 127.529 75.181  1.00 117.65 ? 15  LYS B N   1 
ATOM 4692 C CA  . LYS D 4 15  ? 116.299 127.115 76.577  1.00 117.65 ? 15  LYS B CA  1 
ATOM 4693 C C   . LYS D 4 15  ? 115.297 125.981 76.750  1.00 117.65 ? 15  LYS B C   1 
ATOM 4694 O O   . LYS D 4 15  ? 115.552 125.025 77.493  1.00 117.65 ? 15  LYS B O   1 
ATOM 4695 C CB  . LYS D 4 15  ? 115.917 128.308 77.453  1.00 117.65 ? 15  LYS B CB  1 
ATOM 4696 N N   . ASN D 4 16  ? 114.149 126.069 76.073  1.00 118.13 ? 16  ASN B N   1 
ATOM 4697 C CA  . ASN D 4 16  ? 113.154 125.004 76.159  1.00 118.13 ? 16  ASN B CA  1 
ATOM 4698 C C   . ASN D 4 16  ? 113.690 123.700 75.582  1.00 118.13 ? 16  ASN B C   1 
ATOM 4699 O O   . ASN D 4 16  ? 113.466 122.623 76.149  1.00 118.13 ? 16  ASN B O   1 
ATOM 4700 C CB  . ASN D 4 16  ? 111.872 125.424 75.441  1.00 118.13 ? 16  ASN B CB  1 
ATOM 4701 N N   . GLN D 4 17  ? 114.399 123.775 74.452  1.00 118.72 ? 17  GLN B N   1 
ATOM 4702 C CA  . GLN D 4 17  ? 114.980 122.573 73.863  1.00 118.72 ? 17  GLN B CA  1 
ATOM 4703 C C   . GLN D 4 17  ? 116.030 121.960 74.780  1.00 118.72 ? 17  GLN B C   1 
ATOM 4704 O O   . GLN D 4 17  ? 116.095 120.734 74.931  1.00 118.72 ? 17  GLN B O   1 
ATOM 4705 C CB  . GLN D 4 17  ? 115.583 122.898 72.496  1.00 118.72 ? 17  GLN B CB  1 
ATOM 4706 N N   . ILE D 4 18  ? 116.863 122.799 75.402  1.00 118.38 ? 18  ILE B N   1 
ATOM 4707 C CA  . ILE D 4 18  ? 117.875 122.299 76.329  1.00 118.38 ? 18  ILE B CA  1 
ATOM 4708 C C   . ILE D 4 18  ? 117.216 121.633 77.529  1.00 118.38 ? 18  ILE B C   1 
ATOM 4709 O O   . ILE D 4 18  ? 117.654 120.571 77.986  1.00 118.38 ? 18  ILE B O   1 
ATOM 4710 C CB  . ILE D 4 18  ? 118.817 123.438 76.759  1.00 118.38 ? 18  ILE B CB  1 
ATOM 4711 N N   . ARG D 4 19  ? 116.158 122.249 78.063  1.00 118.90 ? 19  ARG B N   1 
ATOM 4712 C CA  . ARG D 4 19  ? 115.450 121.660 79.195  1.00 118.90 ? 19  ARG B CA  1 
ATOM 4713 C C   . ARG D 4 19  ? 114.816 120.326 78.819  1.00 118.90 ? 19  ARG B C   1 
ATOM 4714 O O   . ARG D 4 19  ? 114.853 119.370 79.602  1.00 118.90 ? 19  ARG B O   1 
ATOM 4715 C CB  . ARG D 4 19  ? 114.390 122.631 79.714  1.00 118.90 ? 19  ARG B CB  1 
ATOM 4716 N N   . ASP D 4 20  ? 114.224 120.244 77.624  1.00 120.09 ? 20  ASP B N   1 
ATOM 4717 C CA  . ASP D 4 20  ? 113.628 118.989 77.178  1.00 120.09 ? 20  ASP B CA  1 
ATOM 4718 C C   . ASP D 4 20  ? 114.684 117.904 77.011  1.00 120.09 ? 20  ASP B C   1 
ATOM 4719 O O   . ASP D 4 20  ? 114.469 116.751 77.404  1.00 120.09 ? 20  ASP B O   1 
ATOM 4720 C CB  . ASP D 4 20  ? 112.867 119.205 75.870  1.00 120.09 ? 20  ASP B CB  1 
ATOM 4721 N N   . ALA D 4 21  ? 115.834 118.254 76.428  1.00 118.37 ? 21  ALA B N   1 
ATOM 4722 C CA  . ALA D 4 21  ? 116.912 117.282 76.274  1.00 118.37 ? 21  ALA B CA  1 
ATOM 4723 C C   . ALA D 4 21  ? 117.432 116.818 77.629  1.00 118.37 ? 21  ALA B C   1 
ATOM 4724 O O   . ALA D 4 21  ? 117.725 115.631 77.816  1.00 118.37 ? 21  ALA B O   1 
ATOM 4725 C CB  . ALA D 4 21  ? 118.044 117.881 75.440  1.00 118.37 ? 21  ALA B CB  1 
ATOM 4726 N N   . ARG D 4 22  ? 117.560 117.742 78.583  1.00 112.89 ? 22  ARG B N   1 
ATOM 4727 C CA  . ARG D 4 22  ? 118.007 117.374 79.923  1.00 112.89 ? 22  ARG B CA  1 
ATOM 4728 C C   . ARG D 4 22  ? 117.007 116.449 80.606  1.00 112.89 ? 22  ARG B C   1 
ATOM 4729 O O   . ARG D 4 22  ? 117.397 115.462 81.242  1.00 112.89 ? 22  ARG B O   1 
ATOM 4730 C CB  . ARG D 4 22  ? 118.232 118.635 80.758  1.00 112.89 ? 22  ARG B CB  1 
ATOM 4731 C CG  . ARG D 4 22  ? 118.616 118.371 82.201  1.00 112.89 ? 22  ARG B CG  1 
ATOM 4732 C CD  . ARG D 4 22  ? 118.904 119.669 82.934  1.00 112.89 ? 22  ARG B CD  1 
ATOM 4733 N NE  . ARG D 4 22  ? 117.729 120.528 83.013  1.00 112.89 ? 22  ARG B NE  1 
ATOM 4734 C CZ  . ARG D 4 22  ? 117.765 121.822 83.300  1.00 112.89 ? 22  ARG B CZ  1 
ATOM 4735 N NH1 . ARG D 4 22  ? 118.906 122.445 83.543  1.00 112.89 ? 22  ARG B NH1 1 
ATOM 4736 N NH2 . ARG D 4 22  ? 116.626 122.509 83.345  1.00 112.89 ? 22  ARG B NH2 1 
ATOM 4737 N N   . LYS D 4 23  ? 115.712 116.749 80.483  1.00 118.07 ? 23  LYS B N   1 
ATOM 4738 C CA  . LYS D 4 23  ? 114.690 115.914 81.103  1.00 118.07 ? 23  LYS B CA  1 
ATOM 4739 C C   . LYS D 4 23  ? 114.547 114.564 80.413  1.00 118.07 ? 23  LYS B C   1 
ATOM 4740 O O   . LYS D 4 23  ? 114.074 113.610 81.041  1.00 118.07 ? 23  LYS B O   1 
ATOM 4741 C CB  . LYS D 4 23  ? 113.345 116.642 81.103  1.00 118.07 ? 23  LYS B CB  1 
ATOM 4742 N N   . ALA D 4 24  ? 114.936 114.464 79.140  1.00 117.89 ? 24  ALA B N   1 
ATOM 4743 C CA  . ALA D 4 24  ? 114.862 113.185 78.442  1.00 117.89 ? 24  ALA B CA  1 
ATOM 4744 C C   . ALA D 4 24  ? 115.789 112.154 79.075  1.00 117.89 ? 24  ALA B C   1 
ATOM 4745 O O   . ALA D 4 24  ? 115.425 110.980 79.210  1.00 117.89 ? 24  ALA B O   1 
ATOM 4746 C CB  . ALA D 4 24  ? 115.197 113.373 76.963  1.00 117.89 ? 24  ALA B CB  1 
ATOM 4747 N N   . CYS D 4 25  ? 116.994 112.573 79.468  1.00 115.00 ? 25  CYS B N   1 
ATOM 4748 C CA  . CYS D 4 25  ? 117.955 111.647 80.056  1.00 115.00 ? 25  CYS B CA  1 
ATOM 4749 C C   . CYS D 4 25  ? 117.552 111.193 81.453  1.00 115.00 ? 25  CYS B C   1 
ATOM 4750 O O   . CYS D 4 25  ? 118.055 110.167 81.924  1.00 115.00 ? 25  CYS B O   1 
ATOM 4751 C CB  . CYS D 4 25  ? 119.343 112.288 80.099  1.00 115.00 ? 25  CYS B CB  1 
ATOM 4752 S SG  . CYS D 4 25  ? 120.065 112.617 78.475  1.00 115.00 ? 25  CYS B SG  1 
ATOM 4753 N N   . ALA D 4 26  ? 116.665 111.924 82.122  1.00 114.80 ? 26  ALA B N   1 
ATOM 4754 C CA  . ALA D 4 26  ? 116.232 111.560 83.466  1.00 114.80 ? 26  ALA B CA  1 
ATOM 4755 C C   . ALA D 4 26  ? 115.233 110.412 83.387  1.00 114.80 ? 26  ALA B C   1 
ATOM 4756 O O   . ALA D 4 26  ? 114.173 110.546 82.766  1.00 114.80 ? 26  ALA B O   1 
ATOM 4757 C CB  . ALA D 4 26  ? 115.617 112.765 84.173  1.00 114.80 ? 26  ALA B CB  1 
ATOM 4758 N N   . ASP D 4 27  ? 115.570 109.286 84.014  1.00 115.40 ? 27  ASP B N   1 
ATOM 4759 C CA  . ASP D 4 27  ? 114.703 108.114 83.983  1.00 115.40 ? 27  ASP B CA  1 
ATOM 4760 C C   . ASP D 4 27  ? 114.480 107.550 85.380  1.00 115.40 ? 27  ASP B C   1 
ATOM 4761 O O   . ASP D 4 27  ? 113.451 106.918 85.642  1.00 115.40 ? 27  ASP B O   1 
ATOM 4762 C CB  . ASP D 4 27  ? 115.293 107.040 83.067  1.00 115.40 ? 27  ASP B CB  1 
ATOM 4763 N N   . ALA D 4 28  ? 115.433 107.771 86.284  1.00 113.21 ? 28  ALA B N   1 
ATOM 4764 C CA  . ALA D 4 28  ? 115.335 107.241 87.638  1.00 113.21 ? 28  ALA B CA  1 
ATOM 4765 C C   . ALA D 4 28  ? 116.063 108.168 88.597  1.00 113.21 ? 28  ALA B C   1 
ATOM 4766 O O   . ALA D 4 28  ? 117.157 108.651 88.287  1.00 113.21 ? 28  ALA B O   1 
ATOM 4767 C CB  . ALA D 4 28  ? 115.917 105.826 87.721  1.00 113.21 ? 28  ALA B CB  1 
ATOM 4768 N N   . THR D 4 29  ? 115.455 108.411 89.755  1.00 108.64 ? 29  THR B N   1 
ATOM 4769 C CA  . THR D 4 29  ? 116.072 109.250 90.769  1.00 108.64 ? 29  THR B CA  1 
ATOM 4770 C C   . THR D 4 29  ? 117.217 108.510 91.456  1.00 108.64 ? 29  THR B C   1 
ATOM 4771 O O   . THR D 4 29  ? 117.306 107.279 91.428  1.00 108.64 ? 29  THR B O   1 
ATOM 4772 C CB  . THR D 4 29  ? 115.039 109.689 91.808  1.00 108.64 ? 29  THR B CB  1 
ATOM 4773 N N   . LEU D 4 30  ? 118.110 109.288 92.074  1.00 97.69  ? 30  LEU B N   1 
ATOM 4774 C CA  . LEU D 4 30  ? 119.244 108.698 92.778  1.00 97.69  ? 30  LEU B CA  1 
ATOM 4775 C C   . LEU D 4 30  ? 118.785 107.835 93.947  1.00 97.69  ? 30  LEU B C   1 
ATOM 4776 O O   . LEU D 4 30  ? 119.301 106.730 94.153  1.00 97.69  ? 30  LEU B O   1 
ATOM 4777 C CB  . LEU D 4 30  ? 120.189 109.799 93.263  1.00 97.69  ? 30  LEU B CB  1 
ATOM 4778 C CG  . LEU D 4 30  ? 121.365 109.365 94.141  1.00 97.69  ? 30  LEU B CG  1 
ATOM 4779 C CD1 . LEU D 4 30  ? 122.216 108.324 93.434  1.00 97.69  ? 30  LEU B CD1 1 
ATOM 4780 C CD2 . LEU D 4 30  ? 122.207 110.566 94.540  1.00 97.69  ? 30  LEU B CD2 1 
ATOM 4781 N N   . SER D 4 31  ? 117.811 108.318 94.720  1.00 103.12 ? 31  SER B N   1 
ATOM 4782 C CA  . SER D 4 31  ? 117.327 107.578 95.879  1.00 103.12 ? 31  SER B CA  1 
ATOM 4783 C C   . SER D 4 31  ? 116.539 106.330 95.502  1.00 103.12 ? 31  SER B C   1 
ATOM 4784 O O   . SER D 4 31  ? 116.313 105.479 96.369  1.00 103.12 ? 31  SER B O   1 
ATOM 4785 C CB  . SER D 4 31  ? 116.462 108.487 96.755  1.00 103.12 ? 31  SER B CB  1 
ATOM 4786 O OG  . SER D 4 31  ? 115.167 108.647 96.202  1.00 103.12 ? 31  SER B OG  1 
ATOM 4787 N N   . GLN D 4 32  ? 116.116 106.201 94.243  1.00 106.52 ? 32  GLN B N   1 
ATOM 4788 C CA  . GLN D 4 32  ? 115.309 105.051 93.848  1.00 106.52 ? 32  GLN B CA  1 
ATOM 4789 C C   . GLN D 4 32  ? 116.134 103.770 93.818  1.00 106.52 ? 32  GLN B C   1 
ATOM 4790 O O   . GLN D 4 32  ? 115.626 102.692 94.148  1.00 106.52 ? 32  GLN B O   1 
ATOM 4791 C CB  . GLN D 4 32  ? 114.667 105.307 92.484  1.00 106.52 ? 32  GLN B CB  1 
ATOM 4792 N N   . ILE D 4 33  ? 117.405 103.863 93.428  1.00 106.96 ? 33  ILE B N   1 
ATOM 4793 C CA  . ILE D 4 33  ? 118.256 102.691 93.249  1.00 106.96 ? 33  ILE B CA  1 
ATOM 4794 C C   . ILE D 4 33  ? 119.257 102.515 94.376  1.00 106.96 ? 33  ILE B C   1 
ATOM 4795 O O   . ILE D 4 33  ? 120.015 101.534 94.365  1.00 106.96 ? 33  ILE B O   1 
ATOM 4796 C CB  . ILE D 4 33  ? 118.984 102.732 91.892  1.00 106.96 ? 33  ILE B CB  1 
ATOM 4797 C CG1 . ILE D 4 33  ? 119.833 104.000 91.779  1.00 106.96 ? 33  ILE B CG1 1 
ATOM 4798 C CG2 . ILE D 4 33  ? 117.984 102.651 90.749  1.00 106.96 ? 33  ILE B CG2 1 
ATOM 4799 C CD1 . ILE D 4 33  ? 120.546 104.136 90.453  1.00 106.96 ? 33  ILE B CD1 1 
ATOM 4800 N N   . THR D 4 34  ? 119.291 103.425 95.348  1.00 102.18 ? 34  THR B N   1 
ATOM 4801 C CA  . THR D 4 34  ? 120.210 103.327 96.473  1.00 102.18 ? 34  THR B CA  1 
ATOM 4802 C C   . THR D 4 34  ? 119.567 102.706 97.707  1.00 102.18 ? 34  THR B C   1 
ATOM 4803 O O   . THR D 4 34  ? 120.190 102.685 98.773  1.00 102.18 ? 34  THR B O   1 
ATOM 4804 C CB  . THR D 4 34  ? 120.775 104.706 96.821  1.00 102.18 ? 34  THR B CB  1 
ATOM 4805 O OG1 . THR D 4 34  ? 119.699 105.631 97.016  1.00 102.18 ? 34  THR B OG1 1 
ATOM 4806 C CG2 . THR D 4 34  ? 121.678 105.207 95.705  1.00 102.18 ? 34  THR B CG2 1 
ATOM 4807 N N   . ASN D 4 35  ? 118.337 102.203 97.588  1.00 104.47 ? 35  ASN B N   1 
ATOM 4808 C CA  . ASN D 4 35  ? 117.665 101.573 98.718  1.00 104.47 ? 35  ASN B CA  1 
ATOM 4809 C C   . ASN D 4 35  ? 118.298 100.248 99.121  1.00 104.47 ? 35  ASN B C   1 
ATOM 4810 O O   . ASN D 4 35  ? 117.986 99.738  100.202 1.00 104.47 ? 35  ASN B O   1 
ATOM 4811 C CB  . ASN D 4 35  ? 116.185 101.359 98.393  1.00 104.47 ? 35  ASN B CB  1 
ATOM 4812 N N   . ASN D 4 36  ? 119.171 99.684  98.290  1.00 103.83 ? 36  ASN B N   1 
ATOM 4813 C CA  . ASN D 4 36  ? 119.832 98.421  98.587  1.00 103.83 ? 36  ASN B CA  1 
ATOM 4814 C C   . ASN D 4 36  ? 121.142 98.598  99.343  1.00 103.83 ? 36  ASN B C   1 
ATOM 4815 O O   . ASN D 4 36  ? 121.827 97.604  99.607  1.00 103.83 ? 36  ASN B O   1 
ATOM 4816 C CB  . ASN D 4 36  ? 120.088 97.644  97.291  1.00 103.83 ? 36  ASN B CB  1 
ATOM 4817 N N   . ILE D 4 37  ? 121.506 99.828  99.696  1.00 93.78  ? 37  ILE B N   1 
ATOM 4818 C CA  . ILE D 4 37  ? 122.742 100.114 100.415 1.00 93.78  ? 37  ILE B CA  1 
ATOM 4819 C C   . ILE D 4 37  ? 122.399 100.404 101.869 1.00 93.78  ? 37  ILE B C   1 
ATOM 4820 O O   . ILE D 4 37  ? 121.506 101.212 102.156 1.00 93.78  ? 37  ILE B O   1 
ATOM 4821 C CB  . ILE D 4 37  ? 123.498 101.293 99.780  1.00 93.78  ? 37  ILE B CB  1 
ATOM 4822 C CG1 . ILE D 4 37  ? 123.613 101.102 98.267  1.00 93.78  ? 37  ILE B CG1 1 
ATOM 4823 C CG2 . ILE D 4 37  ? 124.877 101.438 100.405 1.00 93.78  ? 37  ILE B CG2 1 
ATOM 4824 C CD1 . ILE D 4 37  ? 124.337 99.835  97.862  1.00 93.78  ? 37  ILE B CD1 1 
ATOM 4825 N N   . ASP D 4 38  ? 123.102 99.744  102.784 1.00 87.31  ? 38  ASP B N   1 
ATOM 4826 C CA  . ASP D 4 38  ? 122.831 99.924  104.202 1.00 87.31  ? 38  ASP B CA  1 
ATOM 4827 C C   . ASP D 4 38  ? 123.195 101.342 104.637 1.00 87.31  ? 38  ASP B C   1 
ATOM 4828 O O   . ASP D 4 38  ? 124.204 101.893 104.185 1.00 87.31  ? 38  ASP B O   1 
ATOM 4829 C CB  . ASP D 4 38  ? 123.615 98.907  105.031 1.00 87.31  ? 38  ASP B CB  1 
ATOM 4830 N N   . PRO D 4 39  ? 122.396 101.959 105.504 1.00 81.01  ? 39  PRO B N   1 
ATOM 4831 C CA  . PRO D 4 39  ? 122.716 103.310 105.973 1.00 81.01  ? 39  PRO B CA  1 
ATOM 4832 C C   . PRO D 4 39  ? 123.946 103.317 106.868 1.00 81.01  ? 39  PRO B C   1 
ATOM 4833 O O   . PRO D 4 39  ? 124.299 102.323 107.506 1.00 81.01  ? 39  PRO B O   1 
ATOM 4834 C CB  . PRO D 4 39  ? 121.462 103.724 106.750 1.00 81.01  ? 39  PRO B CB  1 
ATOM 4835 C CG  . PRO D 4 39  ? 120.854 102.436 107.189 1.00 81.01  ? 39  PRO B CG  1 
ATOM 4836 C CD  . PRO D 4 39  ? 121.154 101.441 106.103 1.00 81.01  ? 39  PRO B CD  1 
ATOM 4837 N N   . VAL D 4 40  ? 124.603 104.475 106.905 1.00 72.05  ? 40  VAL B N   1 
ATOM 4838 C CA  . VAL D 4 40  ? 125.805 104.660 107.710 1.00 72.05  ? 40  VAL B CA  1 
ATOM 4839 C C   . VAL D 4 40  ? 125.549 105.743 108.750 1.00 72.05  ? 40  VAL B C   1 
ATOM 4840 O O   . VAL D 4 40  ? 126.463 106.480 109.137 1.00 72.05  ? 40  VAL B O   1 
ATOM 4841 C CB  . VAL D 4 40  ? 127.019 105.009 106.829 1.00 72.05  ? 40  VAL B CB  1 
ATOM 4842 C CG1 . VAL D 4 40  ? 127.413 103.811 105.980 1.00 72.05  ? 40  VAL B CG1 1 
ATOM 4843 C CG2 . VAL D 4 40  ? 126.709 106.210 105.949 1.00 72.05  ? 40  VAL B CG2 1 
ATOM 4844 N N   . GLY D 4 41  ? 124.303 105.839 109.214 1.00 72.43  ? 41  GLY B N   1 
ATOM 4845 C CA  . GLY D 4 41  ? 123.920 106.869 110.164 1.00 72.43  ? 41  GLY B CA  1 
ATOM 4846 C C   . GLY D 4 41  ? 124.499 106.703 111.554 1.00 72.43  ? 41  GLY B C   1 
ATOM 4847 O O   . GLY D 4 41  ? 124.383 107.628 112.365 1.00 72.43  ? 41  GLY B O   1 
ATOM 4848 N N   . ARG D 4 42  ? 125.112 105.556 111.851 1.00 73.76  ? 42  ARG B N   1 
ATOM 4849 C CA  . ARG D 4 42  ? 125.718 105.315 113.161 1.00 73.76  ? 42  ARG B CA  1 
ATOM 4850 C C   . ARG D 4 42  ? 127.118 105.932 113.188 1.00 73.76  ? 42  ARG B C   1 
ATOM 4851 O O   . ARG D 4 42  ? 128.146 105.251 113.191 1.00 73.76  ? 42  ARG B O   1 
ATOM 4852 C CB  . ARG D 4 42  ? 125.754 103.824 113.467 1.00 73.76  ? 42  ARG B CB  1 
ATOM 4853 N N   . ILE D 4 43  ? 127.141 107.263 113.209 1.00 64.73  ? 43  ILE B N   1 
ATOM 4854 C CA  . ILE D 4 43  ? 128.376 108.037 113.200 1.00 64.73  ? 43  ILE B CA  1 
ATOM 4855 C C   . ILE D 4 43  ? 128.342 109.013 114.366 1.00 64.73  ? 43  ILE B C   1 
ATOM 4856 O O   . ILE D 4 43  ? 127.377 109.771 114.518 1.00 64.73  ? 43  ILE B O   1 
ATOM 4857 C CB  . ILE D 4 43  ? 128.567 108.786 111.867 1.00 64.73  ? 43  ILE B CB  1 
ATOM 4858 C CG1 . ILE D 4 43  ? 128.994 107.809 110.770 1.00 64.73  ? 43  ILE B CG1 1 
ATOM 4859 C CG2 . ILE D 4 43  ? 129.589 109.904 112.019 1.00 64.73  ? 43  ILE B CG2 1 
ATOM 4860 C CD1 . ILE D 4 43  ? 129.280 108.468 109.444 1.00 64.73  ? 43  ILE B CD1 1 
ATOM 4861 N N   . GLN D 4 44  ? 129.393 108.994 115.189 1.00 57.15  ? 44  GLN B N   1 
ATOM 4862 C CA  . GLN D 4 44  ? 129.499 109.870 116.361 1.00 57.15  ? 44  GLN B CA  1 
ATOM 4863 C C   . GLN D 4 44  ? 130.932 110.397 116.422 1.00 57.15  ? 44  GLN B C   1 
ATOM 4864 O O   . GLN D 4 44  ? 131.825 109.739 116.963 1.00 57.15  ? 44  GLN B O   1 
ATOM 4865 C CB  . GLN D 4 44  ? 129.111 109.134 117.637 1.00 57.15  ? 44  GLN B CB  1 
ATOM 4866 N N   . MET D 4 45  ? 131.142 111.587 115.865 1.00 44.31  ? 45  MET B N   1 
ATOM 4867 C CA  . MET D 4 45  ? 132.451 112.226 115.870 1.00 44.31  ? 45  MET B CA  1 
ATOM 4868 C C   . MET D 4 45  ? 132.599 113.088 117.117 1.00 44.31  ? 45  MET B C   1 
ATOM 4869 O O   . MET D 4 45  ? 131.665 113.799 117.503 1.00 44.31  ? 45  MET B O   1 
ATOM 4870 C CB  . MET D 4 45  ? 132.644 113.073 114.613 1.00 44.31  ? 45  MET B CB  1 
ATOM 4871 C CG  . MET D 4 45  ? 133.235 112.315 113.435 1.00 44.31  ? 45  MET B CG  1 
ATOM 4872 S SD  . MET D 4 45  ? 133.856 113.410 112.144 1.00 44.31  ? 45  MET B SD  1 
ATOM 4873 C CE  . MET D 4 45  ? 132.700 113.063 110.821 1.00 44.31  ? 45  MET B CE  1 
ATOM 4874 N N   . ARG D 4 46  ? 133.771 113.023 117.741 1.00 35.98  ? 46  ARG B N   1 
ATOM 4875 C CA  . ARG D 4 46  ? 134.073 113.786 118.941 1.00 35.98  ? 46  ARG B CA  1 
ATOM 4876 C C   . ARG D 4 46  ? 135.183 114.789 118.658 1.00 35.98  ? 46  ARG B C   1 
ATOM 4877 O O   . ARG D 4 46  ? 136.005 114.604 117.756 1.00 35.98  ? 46  ARG B O   1 
ATOM 4878 C CB  . ARG D 4 46  ? 134.481 112.860 120.093 1.00 35.98  ? 46  ARG B CB  1 
ATOM 4879 N N   . THR D 4 47  ? 135.197 115.864 119.446 1.00 34.80  ? 47  THR B N   1 
ATOM 4880 C CA  . THR D 4 47  ? 136.183 116.921 119.260 1.00 34.80  ? 47  THR B CA  1 
ATOM 4881 C C   . THR D 4 47  ? 137.558 116.442 119.704 1.00 34.80  ? 47  THR B C   1 
ATOM 4882 O O   . THR D 4 47  ? 137.906 116.540 120.885 1.00 34.80  ? 47  THR B O   1 
ATOM 4883 C CB  . THR D 4 47  ? 135.788 118.179 120.038 1.00 34.80  ? 47  THR B CB  1 
ATOM 4884 O OG1 . THR D 4 47  ? 134.420 118.505 119.766 1.00 34.80  ? 47  THR B OG1 1 
ATOM 4885 C CG2 . THR D 4 47  ? 136.672 119.351 119.638 1.00 34.80  ? 47  THR B CG2 1 
ATOM 4886 N N   . ARG D 4 48  ? 138.342 115.918 118.761 1.00 39.41  ? 48  ARG B N   1 
ATOM 4887 C CA  . ARG D 4 48  ? 139.661 115.399 119.104 1.00 39.41  ? 48  ARG B CA  1 
ATOM 4888 C C   . ARG D 4 48  ? 140.616 116.522 119.486 1.00 39.41  ? 48  ARG B C   1 
ATOM 4889 O O   . ARG D 4 48  ? 141.333 116.424 120.489 1.00 39.41  ? 48  ARG B O   1 
ATOM 4890 C CB  . ARG D 4 48  ? 140.222 114.581 117.941 1.00 39.41  ? 48  ARG B CB  1 
ATOM 4891 C CG  . ARG D 4 48  ? 139.544 113.236 117.763 1.00 39.41  ? 48  ARG B CG  1 
ATOM 4892 C CD  . ARG D 4 48  ? 139.909 112.281 118.886 1.00 39.41  ? 48  ARG B CD  1 
ATOM 4893 N NE  . ARG D 4 48  ? 139.434 110.928 118.627 1.00 39.41  ? 48  ARG B NE  1 
ATOM 4894 C CZ  . ARG D 4 48  ? 138.250 110.465 119.005 1.00 39.41  ? 48  ARG B CZ  1 
ATOM 4895 N NH1 . ARG D 4 48  ? 137.391 111.223 119.667 1.00 39.41  ? 48  ARG B NH1 1 
ATOM 4896 N NH2 . ARG D 4 48  ? 137.920 109.211 118.712 1.00 39.41  ? 48  ARG B NH2 1 
ATOM 4897 N N   . ARG D 4 49  ? 140.637 117.601 118.706 1.00 39.33  ? 49  ARG B N   1 
ATOM 4898 C CA  . ARG D 4 49  ? 141.556 118.703 118.957 1.00 39.33  ? 49  ARG B CA  1 
ATOM 4899 C C   . ARG D 4 49  ? 140.808 120.028 118.959 1.00 39.33  ? 49  ARG B C   1 
ATOM 4900 O O   . ARG D 4 49  ? 139.810 120.199 118.256 1.00 39.33  ? 49  ARG B O   1 
ATOM 4901 C CB  . ARG D 4 49  ? 142.682 118.748 117.912 1.00 39.33  ? 49  ARG B CB  1 
ATOM 4902 C CG  . ARG D 4 49  ? 144.009 118.168 118.380 1.00 39.33  ? 49  ARG B CG  1 
ATOM 4903 C CD  . ARG D 4 49  ? 143.935 116.669 118.602 1.00 39.33  ? 49  ARG B CD  1 
ATOM 4904 N NE  . ARG D 4 49  ? 145.235 116.109 118.949 1.00 39.33  ? 49  ARG B NE  1 
ATOM 4905 C CZ  . ARG D 4 49  ? 145.422 114.882 119.416 1.00 39.33  ? 49  ARG B CZ  1 
ATOM 4906 N NH1 . ARG D 4 49  ? 144.408 114.057 119.616 1.00 39.33  ? 49  ARG B NH1 1 
ATOM 4907 N NH2 . ARG D 4 49  ? 146.657 114.474 119.692 1.00 39.33  ? 49  ARG B NH2 1 
ATOM 4908 N N   . THR D 4 50  ? 141.311 120.971 119.753 1.00 36.66  ? 50  THR B N   1 
ATOM 4909 C CA  . THR D 4 50  ? 140.760 122.319 119.822 1.00 36.66  ? 50  THR B CA  1 
ATOM 4910 C C   . THR D 4 50  ? 141.895 123.315 119.640 1.00 36.66  ? 50  THR B C   1 
ATOM 4911 O O   . THR D 4 50  ? 142.820 123.361 120.458 1.00 36.66  ? 50  THR B O   1 
ATOM 4912 C CB  . THR D 4 50  ? 140.039 122.563 121.151 1.00 36.66  ? 50  THR B CB  1 
ATOM 4913 O OG1 . THR D 4 50  ? 139.156 121.468 121.425 1.00 36.66  ? 50  THR B OG1 1 
ATOM 4914 C CG2 . THR D 4 50  ? 139.235 123.853 121.089 1.00 36.66  ? 50  THR B CG2 1 
ATOM 4915 N N   . LEU D 4 51  ? 141.823 124.107 118.574 1.00 32.46  ? 51  LEU B N   1 
ATOM 4916 C CA  . LEU D 4 51  ? 142.823 125.120 118.269 1.00 32.46  ? 51  LEU B CA  1 
ATOM 4917 C C   . LEU D 4 51  ? 142.274 126.488 118.655 1.00 32.46  ? 51  LEU B C   1 
ATOM 4918 O O   . LEU D 4 51  ? 141.194 126.883 118.196 1.00 32.46  ? 51  LEU B O   1 
ATOM 4919 C CB  . LEU D 4 51  ? 143.198 125.090 116.788 1.00 32.46  ? 51  LEU B CB  1 
ATOM 4920 C CG  . LEU D 4 51  ? 143.475 123.717 116.175 1.00 32.46  ? 51  LEU B CG  1 
ATOM 4921 C CD1 . LEU D 4 51  ? 143.580 123.819 114.662 1.00 32.46  ? 51  LEU B CD1 1 
ATOM 4922 C CD2 . LEU D 4 51  ? 144.738 123.110 116.763 1.00 32.46  ? 51  LEU B CD2 1 
ATOM 4923 N N   . ARG D 4 52  ? 143.021 127.202 119.492 1.00 36.42  ? 52  ARG B N   1 
ATOM 4924 C CA  . ARG D 4 52  ? 142.639 128.509 119.999 1.00 36.42  ? 52  ARG B CA  1 
ATOM 4925 C C   . ARG D 4 52  ? 143.769 129.502 119.760 1.00 36.42  ? 52  ARG B C   1 
ATOM 4926 O O   . ARG D 4 52  ? 144.935 129.127 119.611 1.00 36.42  ? 52  ARG B O   1 
ATOM 4927 C CB  . ARG D 4 52  ? 142.302 128.445 121.495 1.00 36.42  ? 52  ARG B CB  1 
ATOM 4928 C CG  . ARG D 4 52  ? 143.501 128.146 122.382 1.00 36.42  ? 52  ARG B CG  1 
ATOM 4929 C CD  . ARG D 4 52  ? 143.123 128.083 123.854 1.00 36.42  ? 52  ARG B CD  1 
ATOM 4930 N NE  . ARG D 4 52  ? 142.221 126.974 124.141 1.00 36.42  ? 52  ARG B NE  1 
ATOM 4931 C CZ  . ARG D 4 52  ? 140.936 127.110 124.439 1.00 36.42  ? 52  ARG B CZ  1 
ATOM 4932 N NH1 . ARG D 4 52  ? 140.368 128.302 124.521 1.00 36.42  ? 52  ARG B NH1 1 
ATOM 4933 N NH2 . ARG D 4 52  ? 140.204 126.023 124.665 1.00 36.42  ? 52  ARG B NH2 1 
ATOM 4934 N N   . GLY D 4 53  ? 143.410 130.782 119.731 1.00 35.49  ? 53  GLY B N   1 
ATOM 4935 C CA  . GLY D 4 53  ? 144.378 131.832 119.484 1.00 35.49  ? 53  GLY B CA  1 
ATOM 4936 C C   . GLY D 4 53  ? 143.825 132.957 118.635 1.00 35.49  ? 53  GLY B C   1 
ATOM 4937 O O   . GLY D 4 53  ? 144.298 134.095 118.717 1.00 35.49  ? 53  GLY B O   1 
ATOM 4938 N N   . HIS D 4 54  ? 142.825 132.651 117.814 1.00 34.86  ? 54  HIS B N   1 
ATOM 4939 C CA  . HIS D 4 54  ? 142.137 133.687 117.059 1.00 34.86  ? 54  HIS B CA  1 
ATOM 4940 C C   . HIS D 4 54  ? 141.332 134.575 118.001 1.00 34.86  ? 54  HIS B C   1 
ATOM 4941 O O   . HIS D 4 54  ? 140.790 134.118 119.011 1.00 34.86  ? 54  HIS B O   1 
ATOM 4942 C CB  . HIS D 4 54  ? 141.219 133.065 116.008 1.00 34.86  ? 54  HIS B CB  1 
ATOM 4943 C CG  . HIS D 4 54  ? 141.872 132.863 114.676 1.00 34.86  ? 54  HIS B CG  1 
ATOM 4944 N ND1 . HIS D 4 54  ? 142.443 133.895 113.963 1.00 34.86  ? 54  HIS B ND1 1 
ATOM 4945 C CD2 . HIS D 4 54  ? 142.043 131.749 113.926 1.00 34.86  ? 54  HIS B CD2 1 
ATOM 4946 C CE1 . HIS D 4 54  ? 142.936 133.425 112.831 1.00 34.86  ? 54  HIS B CE1 1 
ATOM 4947 N NE2 . HIS D 4 54  ? 142.708 132.125 112.785 1.00 34.86  ? 54  HIS B NE2 1 
ATOM 4948 N N   . LEU D 4 55  ? 141.257 135.861 117.663 1.00 37.33  ? 55  LEU B N   1 
ATOM 4949 C CA  . LEU D 4 55  ? 140.567 136.844 118.490 1.00 37.33  ? 55  LEU B CA  1 
ATOM 4950 C C   . LEU D 4 55  ? 139.430 137.522 117.732 1.00 37.33  ? 55  LEU B C   1 
ATOM 4951 O O   . LEU D 4 55  ? 139.051 138.652 118.046 1.00 37.33  ? 55  LEU B O   1 
ATOM 4952 C CB  . LEU D 4 55  ? 141.553 137.882 119.023 1.00 37.33  ? 55  LEU B CB  1 
ATOM 4953 C CG  . LEU D 4 55  ? 142.561 137.354 120.046 1.00 37.33  ? 55  LEU B CG  1 
ATOM 4954 C CD1 . LEU D 4 55  ? 143.888 138.084 119.926 1.00 37.33  ? 55  LEU B CD1 1 
ATOM 4955 C CD2 . LEU D 4 55  ? 142.006 137.472 121.457 1.00 37.33  ? 55  LEU B CD2 1 
ATOM 4956 N N   . ALA D 4 56  ? 138.875 136.839 116.735 1.00 39.07  ? 56  ALA B N   1 
ATOM 4957 C CA  . ALA D 4 56  ? 137.763 137.369 115.956 1.00 39.07  ? 56  ALA B CA  1 
ATOM 4958 C C   . ALA D 4 56  ? 137.049 136.202 115.285 1.00 39.07  ? 56  ALA B C   1 
ATOM 4959 O O   . ALA D 4 56  ? 137.428 135.039 115.448 1.00 39.07  ? 56  ALA B O   1 
ATOM 4960 C CB  . ALA D 4 56  ? 138.243 138.400 114.931 1.00 39.07  ? 56  ALA B CB  1 
ATOM 4961 N N   . LYS D 4 57  ? 136.007 136.525 114.524 1.00 38.99  ? 57  LYS B N   1 
ATOM 4962 C CA  . LYS D 4 57  ? 135.242 135.500 113.826 1.00 38.99  ? 57  LYS B CA  1 
ATOM 4963 C C   . LYS D 4 57  ? 136.071 134.897 112.700 1.00 38.99  ? 57  LYS B C   1 
ATOM 4964 O O   . LYS D 4 57  ? 136.601 135.619 111.849 1.00 38.99  ? 57  LYS B O   1 
ATOM 4965 C CB  . LYS D 4 57  ? 133.948 136.095 113.271 1.00 38.99  ? 57  LYS B CB  1 
ATOM 4966 C CG  . LYS D 4 57  ? 133.028 136.683 114.328 1.00 38.99  ? 57  LYS B CG  1 
ATOM 4967 C CD  . LYS D 4 57  ? 131.713 137.143 113.720 1.00 38.99  ? 57  LYS B CD  1 
ATOM 4968 C CE  . LYS D 4 57  ? 131.894 138.420 112.916 1.00 38.99  ? 57  LYS B CE  1 
ATOM 4969 N NZ  . LYS D 4 57  ? 130.597 138.944 112.405 1.00 38.99  ? 57  LYS B NZ  1 
ATOM 4970 N N   . ILE D 4 58  ? 136.175 133.572 112.689 1.00 35.96  ? 58  ILE B N   1 
ATOM 4971 C CA  . ILE D 4 58  ? 136.922 132.870 111.651 1.00 35.96  ? 58  ILE B CA  1 
ATOM 4972 C C   . ILE D 4 58  ? 136.036 132.729 110.422 1.00 35.96  ? 58  ILE B C   1 
ATOM 4973 O O   . ILE D 4 58  ? 134.900 132.249 110.512 1.00 35.96  ? 58  ILE B O   1 
ATOM 4974 C CB  . ILE D 4 58  ? 137.398 131.499 112.156 1.00 35.96  ? 58  ILE B CB  1 
ATOM 4975 C CG1 . ILE D 4 58  ? 138.382 131.671 113.314 1.00 35.96  ? 58  ILE B CG1 1 
ATOM 4976 C CG2 . ILE D 4 58  ? 138.037 130.706 111.027 1.00 35.96  ? 58  ILE B CG2 1 
ATOM 4977 C CD1 . ILE D 4 58  ? 138.814 130.367 113.943 1.00 35.96  ? 58  ILE B CD1 1 
ATOM 4978 N N   . TYR D 4 59  ? 136.551 133.150 109.267 1.00 38.31  ? 59  TYR B N   1 
ATOM 4979 C CA  . TYR D 4 59  ? 135.759 133.184 108.044 1.00 38.31  ? 59  TYR B CA  1 
ATOM 4980 C C   . TYR D 4 59  ? 136.133 132.122 107.024 1.00 38.31  ? 59  TYR B C   1 
ATOM 4981 O O   . TYR D 4 59  ? 135.274 131.720 106.237 1.00 38.31  ? 59  TYR B O   1 
ATOM 4982 C CB  . TYR D 4 59  ? 135.864 134.564 107.381 1.00 38.31  ? 59  TYR B CB  1 
ATOM 4983 C CG  . TYR D 4 59  ? 134.720 135.488 107.731 1.00 38.31  ? 59  TYR B CG  1 
ATOM 4984 C CD1 . TYR D 4 59  ? 134.683 136.149 108.951 1.00 38.31  ? 59  TYR B CD1 1 
ATOM 4985 C CD2 . TYR D 4 59  ? 133.672 135.693 106.843 1.00 38.31  ? 59  TYR B CD2 1 
ATOM 4986 C CE1 . TYR D 4 59  ? 133.637 136.992 109.276 1.00 38.31  ? 59  TYR B CE1 1 
ATOM 4987 C CE2 . TYR D 4 59  ? 132.622 136.533 107.159 1.00 38.31  ? 59  TYR B CE2 1 
ATOM 4988 C CZ  . TYR D 4 59  ? 132.610 137.180 108.376 1.00 38.31  ? 59  TYR B CZ  1 
ATOM 4989 O OH  . TYR D 4 59  ? 131.566 138.018 108.695 1.00 38.31  ? 59  TYR B OH  1 
ATOM 4990 N N   . ALA D 4 60  ? 137.379 131.655 107.008 1.00 32.07  ? 60  ALA B N   1 
ATOM 4991 C CA  . ALA D 4 60  ? 137.785 130.678 106.007 1.00 32.07  ? 60  ALA B CA  1 
ATOM 4992 C C   . ALA D 4 60  ? 138.960 129.866 106.527 1.00 32.07  ? 60  ALA B C   1 
ATOM 4993 O O   . ALA D 4 60  ? 139.659 130.270 107.459 1.00 32.07  ? 60  ALA B O   1 
ATOM 4994 C CB  . ALA D 4 60  ? 138.149 131.353 104.681 1.00 32.07  ? 60  ALA B CB  1 
ATOM 4995 N N   . MET D 4 61  ? 139.163 128.708 105.901 1.00 29.29  ? 61  MET B N   1 
ATOM 4996 C CA  . MET D 4 61  ? 140.293 127.841 106.201 1.00 29.29  ? 61  MET B CA  1 
ATOM 4997 C C   . MET D 4 61  ? 140.568 126.961 104.990 1.00 29.29  ? 61  MET B C   1 
ATOM 4998 O O   . MET D 4 61  ? 139.743 126.843 104.081 1.00 29.29  ? 61  MET B O   1 
ATOM 4999 C CB  . MET D 4 61  ? 140.039 126.982 107.442 1.00 29.29  ? 61  MET B CB  1 
ATOM 5000 C CG  . MET D 4 61  ? 138.855 126.041 107.320 1.00 29.29  ? 61  MET B CG  1 
ATOM 5001 S SD  . MET D 4 61  ? 139.371 124.398 106.790 1.00 29.29  ? 61  MET B SD  1 
ATOM 5002 C CE  . MET D 4 61  ? 140.537 123.997 108.083 1.00 29.29  ? 61  MET B CE  1 
ATOM 5003 N N   . HIS D 4 62  ? 141.745 126.339 104.987 1.00 29.27  ? 62  HIS B N   1 
ATOM 5004 C CA  . HIS D 4 62  ? 142.117 125.415 103.919 1.00 29.27  ? 62  HIS B CA  1 
ATOM 5005 C C   . HIS D 4 62  ? 143.107 124.400 104.465 1.00 29.27  ? 62  HIS B C   1 
ATOM 5006 O O   . HIS D 4 62  ? 144.128 124.778 105.046 1.00 29.27  ? 62  HIS B O   1 
ATOM 5007 C CB  . HIS D 4 62  ? 142.713 126.163 102.725 1.00 29.27  ? 62  HIS B CB  1 
ATOM 5008 C CG  . HIS D 4 62  ? 142.817 125.331 101.485 1.00 29.27  ? 62  HIS B CG  1 
ATOM 5009 N ND1 . HIS D 4 62  ? 143.913 124.543 101.206 1.00 29.27  ? 62  HIS B ND1 1 
ATOM 5010 C CD2 . HIS D 4 62  ? 141.959 125.160 100.452 1.00 29.27  ? 62  HIS B CD2 1 
ATOM 5011 C CE1 . HIS D 4 62  ? 143.727 123.925 100.054 1.00 29.27  ? 62  HIS B CE1 1 
ATOM 5012 N NE2 . HIS D 4 62  ? 142.549 124.282 99.575  1.00 29.27  ? 62  HIS B NE2 1 
ATOM 5013 N N   . TRP D 4 63  ? 142.803 123.118 104.278 1.00 31.44  ? 63  TRP B N   1 
ATOM 5014 C CA  . TRP D 4 63  ? 143.701 122.057 104.710 1.00 31.44  ? 63  TRP B CA  1 
ATOM 5015 C C   . TRP D 4 63  ? 144.917 121.969 103.796 1.00 31.44  ? 63  TRP B C   1 
ATOM 5016 O O   . TRP D 4 63  ? 144.872 122.346 102.622 1.00 31.44  ? 63  TRP B O   1 
ATOM 5017 C CB  . TRP D 4 63  ? 142.974 120.713 104.729 1.00 31.44  ? 63  TRP B CB  1 
ATOM 5018 C CG  . TRP D 4 63  ? 142.377 120.362 106.054 1.00 31.44  ? 63  TRP B CG  1 
ATOM 5019 C CD1 . TRP D 4 63  ? 141.056 120.379 106.388 1.00 31.44  ? 63  TRP B CD1 1 
ATOM 5020 C CD2 . TRP D 4 63  ? 143.082 119.933 107.225 1.00 31.44  ? 63  TRP B CD2 1 
ATOM 5021 N NE1 . TRP D 4 63  ? 140.893 119.989 107.694 1.00 31.44  ? 63  TRP B NE1 1 
ATOM 5022 C CE2 . TRP D 4 63  ? 142.122 119.711 108.231 1.00 31.44  ? 63  TRP B CE2 1 
ATOM 5023 C CE3 . TRP D 4 63  ? 144.431 119.716 107.521 1.00 31.44  ? 63  TRP B CE3 1 
ATOM 5024 C CZ2 . TRP D 4 63  ? 142.467 119.281 109.511 1.00 31.44  ? 63  TRP B CZ2 1 
ATOM 5025 C CZ3 . TRP D 4 63  ? 144.772 119.291 108.792 1.00 31.44  ? 63  TRP B CZ3 1 
ATOM 5026 C CH2 . TRP D 4 63  ? 143.794 119.078 109.771 1.00 31.44  ? 63  TRP B CH2 1 
ATOM 5027 N N   . GLY D 4 64  ? 146.015 121.457 104.351 1.00 36.07  ? 64  GLY B N   1 
ATOM 5028 C CA  . GLY D 4 64  ? 147.216 121.270 103.571 1.00 36.07  ? 64  GLY B CA  1 
ATOM 5029 C C   . GLY D 4 64  ? 147.254 119.933 102.857 1.00 36.07  ? 64  GLY B C   1 
ATOM 5030 O O   . GLY D 4 64  ? 146.490 119.013 103.152 1.00 36.07  ? 64  GLY B O   1 
ATOM 5031 N N   . THR D 4 65  ? 148.168 119.835 101.889 1.00 40.26  ? 65  THR B N   1 
ATOM 5032 C CA  . THR D 4 65  ? 148.349 118.581 101.164 1.00 40.26  ? 65  THR B CA  1 
ATOM 5033 C C   . THR D 4 65  ? 148.864 117.481 102.084 1.00 40.26  ? 65  THR B C   1 
ATOM 5034 O O   . THR D 4 65  ? 148.433 116.327 101.985 1.00 40.26  ? 65  THR B O   1 
ATOM 5035 C CB  . THR D 4 65  ? 149.301 118.787 99.986  1.00 40.26  ? 65  THR B CB  1 
ATOM 5036 O OG1 . THR D 4 65  ? 148.823 119.860 99.165  1.00 40.26  ? 65  THR B OG1 1 
ATOM 5037 C CG2 . THR D 4 65  ? 149.396 117.521 99.147  1.00 40.26  ? 65  THR B CG2 1 
ATOM 5038 N N   . ASP D 4 66  ? 149.784 117.821 102.990 1.00 41.51  ? 66  ASP B N   1 
ATOM 5039 C CA  . ASP D 4 66  ? 150.311 116.852 103.942 1.00 41.51  ? 66  ASP B CA  1 
ATOM 5040 C C   . ASP D 4 66  ? 149.302 116.468 105.016 1.00 41.51  ? 66  ASP B C   1 
ATOM 5041 O O   . ASP D 4 66  ? 149.579 115.548 105.794 1.00 41.51  ? 66  ASP B O   1 
ATOM 5042 C CB  . ASP D 4 66  ? 151.582 117.397 104.597 1.00 41.51  ? 66  ASP B CB  1 
ATOM 5043 C CG  . ASP D 4 66  ? 151.385 118.774 105.200 1.00 41.51  ? 66  ASP B CG  1 
ATOM 5044 O OD1 . ASP D 4 66  ? 150.304 119.366 104.997 1.00 41.51  ? 66  ASP B OD1 1 
ATOM 5045 O OD2 . ASP D 4 66  ? 152.311 119.263 105.880 1.00 41.51  ? 66  ASP B OD2 1 
ATOM 5046 N N   . SER D 4 67  ? 148.160 117.157 105.085 1.00 38.34  ? 67  SER B N   1 
ATOM 5047 C CA  . SER D 4 67  ? 147.103 116.871 106.057 1.00 38.34  ? 67  SER B CA  1 
ATOM 5048 C C   . SER D 4 67  ? 147.584 117.060 107.493 1.00 38.34  ? 67  SER B C   1 
ATOM 5049 O O   . SER D 4 67  ? 147.097 116.401 108.415 1.00 38.34  ? 67  SER B O   1 
ATOM 5050 C CB  . SER D 4 67  ? 146.532 115.461 105.866 1.00 38.34  ? 67  SER B CB  1 
ATOM 5051 O OG  . SER D 4 67  ? 146.255 115.205 104.501 1.00 38.34  ? 67  SER B OG  1 
ATOM 5052 N N   . ARG D 4 68  ? 148.543 117.963 107.693 1.00 35.23  ? 68  ARG B N   1 
ATOM 5053 C CA  . ARG D 4 68  ? 149.053 118.248 109.028 1.00 35.23  ? 68  ARG B CA  1 
ATOM 5054 C C   . ARG D 4 68  ? 149.000 119.743 109.314 1.00 35.23  ? 68  ARG B C   1 
ATOM 5055 O O   . ARG D 4 68  ? 148.779 120.157 110.457 1.00 35.23  ? 68  ARG B O   1 
ATOM 5056 C CB  . ARG D 4 68  ? 150.482 117.722 109.179 1.00 35.23  ? 68  ARG B CB  1 
ATOM 5057 C CG  . ARG D 4 68  ? 151.038 117.833 110.588 1.00 35.23  ? 68  ARG B CG  1 
ATOM 5058 C CD  . ARG D 4 68  ? 152.400 117.169 110.702 1.00 35.23  ? 68  ARG B CD  1 
ATOM 5059 N NE  . ARG D 4 68  ? 152.938 117.263 112.054 1.00 35.23  ? 68  ARG B NE  1 
ATOM 5060 C CZ  . ARG D 4 68  ? 154.085 116.724 112.443 1.00 35.23  ? 68  ARG B CZ  1 
ATOM 5061 N NH1 . ARG D 4 68  ? 154.847 116.040 111.605 1.00 35.23  ? 68  ARG B NH1 1 
ATOM 5062 N NH2 . ARG D 4 68  ? 154.478 116.875 113.704 1.00 35.23  ? 68  ARG B NH2 1 
ATOM 5063 N N   . LEU D 4 69  ? 149.196 120.559 108.283 1.00 31.91  ? 69  LEU B N   1 
ATOM 5064 C CA  . LEU D 4 69  ? 149.186 122.009 108.413 1.00 31.91  ? 69  LEU B CA  1 
ATOM 5065 C C   . LEU D 4 69  ? 147.917 122.576 107.793 1.00 31.91  ? 69  LEU B C   1 
ATOM 5066 O O   . LEU D 4 69  ? 147.513 122.171 106.700 1.00 31.91  ? 69  LEU B O   1 
ATOM 5067 C CB  . LEU D 4 69  ? 150.415 122.624 107.739 1.00 31.91  ? 69  LEU B CB  1 
ATOM 5068 C CG  . LEU D 4 69  ? 151.785 122.083 108.153 1.00 31.91  ? 69  LEU B CG  1 
ATOM 5069 C CD1 . LEU D 4 69  ? 152.881 122.692 107.294 1.00 31.91  ? 69  LEU B CD1 1 
ATOM 5070 C CD2 . LEU D 4 69  ? 152.053 122.338 109.627 1.00 31.91  ? 69  LEU B CD2 1 
ATOM 5071 N N   . LEU D 4 70  ? 147.288 123.515 108.498 1.00 29.91  ? 70  LEU B N   1 
ATOM 5072 C CA  . LEU D 4 70  ? 146.070 124.150 108.019 1.00 29.91  ? 70  LEU B CA  1 
ATOM 5073 C C   . LEU D 4 70  ? 146.151 125.651 108.251 1.00 29.91  ? 70  LEU B C   1 
ATOM 5074 O O   . LEU D 4 70  ? 146.715 126.105 109.251 1.00 29.91  ? 70  LEU B O   1 
ATOM 5075 C CB  . LEU D 4 70  ? 144.824 123.563 108.706 1.00 29.91  ? 70  LEU B CB  1 
ATOM 5076 C CG  . LEU D 4 70  ? 144.655 123.687 110.224 1.00 29.91  ? 70  LEU B CG  1 
ATOM 5077 C CD1 . LEU D 4 70  ? 143.924 124.968 110.613 1.00 29.91  ? 70  LEU B CD1 1 
ATOM 5078 C CD2 . LEU D 4 70  ? 143.935 122.471 110.783 1.00 29.91  ? 70  LEU B CD2 1 
ATOM 5079 N N   . VAL D 4 71  ? 145.578 126.415 107.325 1.00 30.00  ? 71  VAL B N   1 
ATOM 5080 C CA  . VAL D 4 71  ? 145.540 127.869 107.416 1.00 30.00  ? 71  VAL B CA  1 
ATOM 5081 C C   . VAL D 4 71  ? 144.180 128.292 107.951 1.00 30.00  ? 71  VAL B C   1 
ATOM 5082 O O   . VAL D 4 71  ? 143.176 127.589 107.791 1.00 30.00  ? 71  VAL B O   1 
ATOM 5083 C CB  . VAL D 4 71  ? 145.835 128.531 106.053 1.00 30.00  ? 71  VAL B CB  1 
ATOM 5084 C CG1 . VAL D 4 71  ? 147.195 128.095 105.535 1.00 30.00  ? 71  VAL B CG1 1 
ATOM 5085 C CG2 . VAL D 4 71  ? 144.746 128.194 105.048 1.00 30.00  ? 71  VAL B CG2 1 
ATOM 5086 N N   . SER D 4 72  ? 144.150 129.450 108.605 1.00 31.30  ? 72  SER B N   1 
ATOM 5087 C CA  . SER D 4 72  ? 142.917 129.982 109.169 1.00 31.30  ? 72  SER B CA  1 
ATOM 5088 C C   . SER D 4 72  ? 142.951 131.500 109.090 1.00 31.30  ? 72  SER B C   1 
ATOM 5089 O O   . SER D 4 72  ? 143.973 132.119 109.405 1.00 31.30  ? 72  SER B O   1 
ATOM 5090 C CB  . SER D 4 72  ? 142.730 129.527 110.621 1.00 31.30  ? 72  SER B CB  1 
ATOM 5091 O OG  . SER D 4 72  ? 143.760 130.032 111.451 1.00 31.30  ? 72  SER B OG  1 
ATOM 5092 N N   . ALA D 4 73  ? 141.832 132.087 108.671 1.00 32.92  ? 73  ALA B N   1 
ATOM 5093 C CA  . ALA D 4 73  ? 141.691 133.528 108.520 1.00 32.92  ? 73  ALA B CA  1 
ATOM 5094 C C   . ALA D 4 73  ? 140.517 134.011 109.357 1.00 32.92  ? 73  ALA B C   1 
ATOM 5095 O O   . ALA D 4 73  ? 139.448 133.390 109.352 1.00 32.92  ? 73  ALA B O   1 
ATOM 5096 C CB  . ALA D 4 73  ? 141.485 133.911 107.053 1.00 32.92  ? 73  ALA B CB  1 
ATOM 5097 N N   . SER D 4 74  ? 140.715 135.120 110.067 1.00 36.22  ? 74  SER B N   1 
ATOM 5098 C CA  . SER D 4 74  ? 139.675 135.713 110.893 1.00 36.22  ? 74  SER B CA  1 
ATOM 5099 C C   . SER D 4 74  ? 139.682 137.222 110.682 1.00 36.22  ? 74  SER B C   1 
ATOM 5100 O O   . SER D 4 74  ? 140.514 137.766 109.949 1.00 36.22  ? 74  SER B O   1 
ATOM 5101 C CB  . SER D 4 74  ? 139.863 135.350 112.371 1.00 36.22  ? 74  SER B CB  1 
ATOM 5102 O OG  . SER D 4 74  ? 141.067 135.891 112.879 1.00 36.22  ? 74  SER B OG  1 
ATOM 5103 N N   . GLN D 4 75  ? 138.740 137.903 111.336 1.00 40.71  ? 75  GLN B N   1 
ATOM 5104 C CA  . GLN D 4 75  ? 138.566 139.338 111.155 1.00 40.71  ? 75  GLN B CA  1 
ATOM 5105 C C   . GLN D 4 75  ? 139.608 140.172 111.888 1.00 40.71  ? 75  GLN B C   1 
ATOM 5106 O O   . GLN D 4 75  ? 139.661 141.388 111.675 1.00 40.71  ? 75  GLN B O   1 
ATOM 5107 C CB  . GLN D 4 75  ? 137.166 139.758 111.609 1.00 40.71  ? 75  GLN B CB  1 
ATOM 5108 C CG  . GLN D 4 75  ? 136.047 139.194 110.750 1.00 40.71  ? 75  GLN B CG  1 
ATOM 5109 C CD  . GLN D 4 75  ? 135.744 140.065 109.547 1.00 40.71  ? 75  GLN B CD  1 
ATOM 5110 O OE1 . GLN D 4 75  ? 135.624 141.284 109.664 1.00 40.71  ? 75  GLN B OE1 1 
ATOM 5111 N NE2 . GLN D 4 75  ? 135.623 139.443 108.380 1.00 40.71  ? 75  GLN B NE2 1 
ATOM 5112 N N   . ASP D 4 76  ? 140.433 139.562 112.742 1.00 39.84  ? 76  ASP B N   1 
ATOM 5113 C CA  . ASP D 4 76  ? 141.458 140.318 113.450 1.00 39.84  ? 76  ASP B CA  1 
ATOM 5114 C C   . ASP D 4 76  ? 142.617 140.726 112.551 1.00 39.84  ? 76  ASP B C   1 
ATOM 5115 O O   . ASP D 4 76  ? 143.466 141.512 112.984 1.00 39.84  ? 76  ASP B O   1 
ATOM 5116 C CB  . ASP D 4 76  ? 141.985 139.512 114.640 1.00 39.84  ? 76  ASP B CB  1 
ATOM 5117 C CG  . ASP D 4 76  ? 142.501 138.145 114.239 1.00 39.84  ? 76  ASP B CG  1 
ATOM 5118 O OD1 . ASP D 4 76  ? 142.338 137.766 113.060 1.00 39.84  ? 76  ASP B OD1 1 
ATOM 5119 O OD2 . ASP D 4 76  ? 143.071 137.447 115.103 1.00 39.84  ? 76  ASP B OD2 1 
ATOM 5120 N N   . GLY D 4 77  ? 142.675 140.216 111.323 1.00 38.81  ? 77  GLY B N   1 
ATOM 5121 C CA  . GLY D 4 77  ? 143.748 140.553 110.413 1.00 38.81  ? 77  GLY B CA  1 
ATOM 5122 C C   . GLY D 4 77  ? 144.953 139.646 110.476 1.00 38.81  ? 77  GLY B C   1 
ATOM 5123 O O   . GLY D 4 77  ? 146.022 140.029 109.986 1.00 38.81  ? 77  GLY B O   1 
ATOM 5124 N N   . LYS D 4 78  ? 144.823 138.460 111.064 1.00 36.27  ? 78  LYS B N   1 
ATOM 5125 C CA  . LYS D 4 78  ? 145.929 137.524 111.206 1.00 36.27  ? 78  LYS B CA  1 
ATOM 5126 C C   . LYS D 4 78  ? 145.607 136.236 110.462 1.00 36.27  ? 78  LYS B C   1 
ATOM 5127 O O   . LYS D 4 78  ? 144.522 135.671 110.631 1.00 36.27  ? 78  LYS B O   1 
ATOM 5128 C CB  . LYS D 4 78  ? 146.210 137.224 112.681 1.00 36.27  ? 78  LYS B CB  1 
ATOM 5129 C CG  . LYS D 4 78  ? 146.701 138.421 113.477 1.00 36.27  ? 78  LYS B CG  1 
ATOM 5130 C CD  . LYS D 4 78  ? 148.211 138.565 113.384 1.00 36.27  ? 78  LYS B CD  1 
ATOM 5131 C CE  . LYS D 4 78  ? 148.657 139.958 113.795 1.00 36.27  ? 78  LYS B CE  1 
ATOM 5132 N NZ  . LYS D 4 78  ? 147.824 141.017 113.160 1.00 36.27  ? 78  LYS B NZ  1 
ATOM 5133 N N   . LEU D 4 79  ? 146.550 135.781 109.642 1.00 32.46  ? 79  LEU B N   1 
ATOM 5134 C CA  . LEU D 4 79  ? 146.464 134.489 108.969 1.00 32.46  ? 79  LEU B CA  1 
ATOM 5135 C C   . LEU D 4 79  ? 147.337 133.510 109.744 1.00 32.46  ? 79  LEU B C   1 
ATOM 5136 O O   . LEU D 4 79  ? 148.561 133.658 109.778 1.00 32.46  ? 79  LEU B O   1 
ATOM 5137 C CB  . LEU D 4 79  ? 146.918 134.603 107.515 1.00 32.46  ? 79  LEU B CB  1 
ATOM 5138 C CG  . LEU D 4 79  ? 146.456 133.526 106.532 1.00 32.46  ? 79  LEU B CG  1 
ATOM 5139 C CD1 . LEU D 4 79  ? 144.988 133.701 106.193 1.00 32.46  ? 79  LEU B CD1 1 
ATOM 5140 C CD2 . LEU D 4 79  ? 147.306 133.557 105.272 1.00 32.46  ? 79  LEU B CD2 1 
ATOM 5141 N N   . ILE D 4 80  ? 146.715 132.517 110.373 1.00 30.28  ? 80  ILE B N   1 
ATOM 5142 C CA  . ILE D 4 80  ? 147.418 131.605 111.269 1.00 30.28  ? 80  ILE B CA  1 
ATOM 5143 C C   . ILE D 4 80  ? 147.540 130.245 110.598 1.00 30.28  ? 80  ILE B C   1 
ATOM 5144 O O   . ILE D 4 80  ? 146.536 129.654 110.188 1.00 30.28  ? 80  ILE B O   1 
ATOM 5145 C CB  . ILE D 4 80  ? 146.709 131.483 112.629 1.00 30.28  ? 80  ILE B CB  1 
ATOM 5146 C CG1 . ILE D 4 80  ? 146.446 132.868 113.219 1.00 30.28  ? 80  ILE B CG1 1 
ATOM 5147 C CG2 . ILE D 4 80  ? 147.554 130.662 113.588 1.00 30.28  ? 80  ILE B CG2 1 
ATOM 5148 C CD1 . ILE D 4 80  ? 145.816 132.831 114.594 1.00 30.28  ? 80  ILE B CD1 1 
ATOM 5149 N N   . ILE D 4 81  ? 148.769 129.749 110.497 1.00 30.23  ? 81  ILE B N   1 
ATOM 5150 C CA  . ILE D 4 81  ? 149.057 128.418 109.977 1.00 30.23  ? 81  ILE B CA  1 
ATOM 5151 C C   . ILE D 4 81  ? 149.433 127.543 111.162 1.00 30.23  ? 81  ILE B C   1 
ATOM 5152 O O   . ILE D 4 81  ? 150.430 127.813 111.847 1.00 30.23  ? 81  ILE B O   1 
ATOM 5153 C CB  . ILE D 4 81  ? 150.178 128.447 108.929 1.00 30.23  ? 81  ILE B CB  1 
ATOM 5154 C CG1 . ILE D 4 81  ? 149.785 129.346 107.758 1.00 30.23  ? 81  ILE B CG1 1 
ATOM 5155 C CG2 . ILE D 4 81  ? 150.492 127.039 108.446 1.00 30.23  ? 81  ILE B CG2 1 
ATOM 5156 C CD1 . ILE D 4 81  ? 150.918 129.639 106.814 1.00 30.23  ? 81  ILE B CD1 1 
ATOM 5157 N N   . TRP D 4 82  ? 148.645 126.497 111.391 1.00 30.07  ? 82  TRP B N   1 
ATOM 5158 C CA  . TRP D 4 82  ? 148.737 125.665 112.580 1.00 30.07  ? 82  TRP B CA  1 
ATOM 5159 C C   . TRP D 4 82  ? 149.436 124.345 112.275 1.00 30.07  ? 82  TRP B C   1 
ATOM 5160 O O   . TRP D 4 82  ? 149.751 124.021 111.128 1.00 30.07  ? 82  TRP B O   1 
ATOM 5161 C CB  . TRP D 4 82  ? 147.343 125.383 113.153 1.00 30.07  ? 82  TRP B CB  1 
ATOM 5162 C CG  . TRP D 4 82  ? 146.459 126.584 113.310 1.00 30.07  ? 82  TRP B CG  1 
ATOM 5163 C CD1 . TRP D 4 82  ? 145.877 127.314 112.314 1.00 30.07  ? 82  TRP B CD1 1 
ATOM 5164 C CD2 . TRP D 4 82  ? 146.028 127.175 114.542 1.00 30.07  ? 82  TRP B CD2 1 
ATOM 5165 N NE1 . TRP D 4 82  ? 145.126 128.332 112.848 1.00 30.07  ? 82  TRP B NE1 1 
ATOM 5166 C CE2 . TRP D 4 82  ? 145.200 128.267 114.215 1.00 30.07  ? 82  TRP B CE2 1 
ATOM 5167 C CE3 . TRP D 4 82  ? 146.268 126.891 115.890 1.00 30.07  ? 82  TRP B CE3 1 
ATOM 5168 C CZ2 . TRP D 4 82  ? 144.613 129.076 115.185 1.00 30.07  ? 82  TRP B CZ2 1 
ATOM 5169 C CZ3 . TRP D 4 82  ? 145.684 127.695 116.851 1.00 30.07  ? 82  TRP B CZ3 1 
ATOM 5170 C CH2 . TRP D 4 82  ? 144.866 128.773 116.494 1.00 30.07  ? 82  TRP B CH2 1 
ATOM 5171 N N   . ASP D 4 83  ? 149.672 123.578 113.336 1.00 34.63  ? 83  ASP B N   1 
ATOM 5172 C CA  . ASP D 4 83  ? 150.135 122.194 113.262 1.00 34.63  ? 83  ASP B CA  1 
ATOM 5173 C C   . ASP D 4 83  ? 149.107 121.367 114.030 1.00 34.63  ? 83  ASP B C   1 
ATOM 5174 O O   . ASP D 4 83  ? 149.200 121.221 115.251 1.00 34.63  ? 83  ASP B O   1 
ATOM 5175 C CB  . ASP D 4 83  ? 151.544 122.038 113.838 1.00 34.63  ? 83  ASP B CB  1 
ATOM 5176 C CG  . ASP D 4 83  ? 152.194 120.722 113.452 1.00 34.63  ? 83  ASP B CG  1 
ATOM 5177 O OD1 . ASP D 4 83  ? 151.463 119.744 113.191 1.00 34.63  ? 83  ASP B OD1 1 
ATOM 5178 O OD2 . ASP D 4 83  ? 153.441 120.665 113.411 1.00 34.63  ? 83  ASP B OD2 1 
ATOM 5179 N N   . SER D 4 84  ? 148.122 120.830 113.306 1.00 37.56  ? 84  SER B N   1 
ATOM 5180 C CA  . SER D 4 84  ? 147.006 120.140 113.944 1.00 37.56  ? 84  SER B CA  1 
ATOM 5181 C C   . SER D 4 84  ? 147.442 118.895 114.706 1.00 37.56  ? 84  SER B C   1 
ATOM 5182 O O   . SER D 4 84  ? 146.722 118.453 115.608 1.00 37.56  ? 84  SER B O   1 
ATOM 5183 C CB  . SER D 4 84  ? 145.955 119.766 112.898 1.00 37.56  ? 84  SER B CB  1 
ATOM 5184 O OG  . SER D 4 84  ? 146.318 118.580 112.212 1.00 37.56  ? 84  SER B OG  1 
ATOM 5185 N N   . TYR D 4 85  ? 148.594 118.315 114.360 1.00 37.14  ? 85  TYR B N   1 
ATOM 5186 C CA  . TYR D 4 85  ? 149.058 117.121 115.060 1.00 37.14  ? 85  TYR B CA  1 
ATOM 5187 C C   . TYR D 4 85  ? 149.343 117.413 116.529 1.00 37.14  ? 85  TYR B C   1 
ATOM 5188 O O   . TYR D 4 85  ? 148.988 116.618 117.407 1.00 37.14  ? 85  TYR B O   1 
ATOM 5189 C CB  . TYR D 4 85  ? 150.305 116.562 114.375 1.00 37.14  ? 85  TYR B CB  1 
ATOM 5190 C CG  . TYR D 4 85  ? 150.010 115.593 113.251 1.00 37.14  ? 85  TYR B CG  1 
ATOM 5191 C CD1 . TYR D 4 85  ? 148.830 115.678 112.525 1.00 37.14  ? 85  TYR B CD1 1 
ATOM 5192 C CD2 . TYR D 4 85  ? 150.914 114.594 112.916 1.00 37.14  ? 85  TYR B CD2 1 
ATOM 5193 C CE1 . TYR D 4 85  ? 148.558 114.796 111.497 1.00 37.14  ? 85  TYR B CE1 1 
ATOM 5194 C CE2 . TYR D 4 85  ? 150.650 113.706 111.890 1.00 37.14  ? 85  TYR B CE2 1 
ATOM 5195 C CZ  . TYR D 4 85  ? 149.471 113.812 111.184 1.00 37.14  ? 85  TYR B CZ  1 
ATOM 5196 O OH  . TYR D 4 85  ? 149.205 112.931 110.162 1.00 37.14  ? 85  TYR B OH  1 
ATOM 5197 N N   . THR D 4 86  ? 149.981 118.548 116.817 1.00 36.09  ? 86  THR B N   1 
ATOM 5198 C CA  . THR D 4 86  ? 150.357 118.905 118.180 1.00 36.09  ? 86  THR B CA  1 
ATOM 5199 C C   . THR D 4 86  ? 149.741 120.221 118.641 1.00 36.09  ? 86  THR B C   1 
ATOM 5200 O O   . THR D 4 86  ? 150.162 120.758 119.673 1.00 36.09  ? 86  THR B O   1 
ATOM 5201 C CB  . THR D 4 86  ? 151.882 118.979 118.313 1.00 36.09  ? 86  THR B CB  1 
ATOM 5202 O OG1 . THR D 4 86  ? 152.379 120.075 117.535 1.00 36.09  ? 86  THR B OG1 1 
ATOM 5203 C CG2 . THR D 4 86  ? 152.526 117.687 117.830 1.00 36.09  ? 86  THR B CG2 1 
ATOM 5204 N N   . THR D 4 87  ? 148.761 120.753 117.907 1.00 37.15  ? 87  THR B N   1 
ATOM 5205 C CA  . THR D 4 87  ? 148.089 122.013 118.231 1.00 37.15  ? 87  THR B CA  1 
ATOM 5206 C C   . THR D 4 87  ? 149.067 123.175 118.369 1.00 37.15  ? 87  THR B C   1 
ATOM 5207 O O   . THR D 4 87  ? 148.835 124.094 119.161 1.00 37.15  ? 87  THR B O   1 
ATOM 5208 C CB  . THR D 4 87  ? 147.242 121.892 119.505 1.00 37.15  ? 87  THR B CB  1 
ATOM 5209 O OG1 . THR D 4 87  ? 148.101 121.817 120.650 1.00 37.15  ? 87  THR B OG1 1 
ATOM 5210 C CG2 . THR D 4 87  ? 146.371 120.650 119.451 1.00 37.15  ? 87  THR B CG2 1 
ATOM 5211 N N   . ASN D 4 88  ? 150.158 123.154 117.610 1.00 36.31  ? 88  ASN B N   1 
ATOM 5212 C CA  . ASN D 4 88  ? 151.174 124.195 117.682 1.00 36.31  ? 88  ASN B CA  1 
ATOM 5213 C C   . ASN D 4 88  ? 151.011 125.160 116.516 1.00 36.31  ? 88  ASN B C   1 
ATOM 5214 O O   . ASN D 4 88  ? 150.886 124.735 115.363 1.00 36.31  ? 88  ASN B O   1 
ATOM 5215 C CB  . ASN D 4 88  ? 152.575 123.582 117.668 1.00 36.31  ? 88  ASN B CB  1 
ATOM 5216 C CG  . ASN D 4 88  ? 153.119 123.337 119.062 1.00 36.31  ? 88  ASN B CG  1 
ATOM 5217 O OD1 . ASN D 4 88  ? 152.624 123.897 120.041 1.00 36.31  ? 88  ASN B OD1 1 
ATOM 5218 N ND2 . ASN D 4 88  ? 154.145 122.500 119.158 1.00 36.31  ? 88  ASN B ND2 1 
ATOM 5219 N N   . LYS D 4 89  ? 151.009 126.455 116.818 1.00 34.72  ? 89  LYS B N   1 
ATOM 5220 C CA  . LYS D 4 89  ? 150.952 127.468 115.775 1.00 34.72  ? 89  LYS B CA  1 
ATOM 5221 C C   . LYS D 4 89  ? 152.310 127.578 115.096 1.00 34.72  ? 89  LYS B C   1 
ATOM 5222 O O   . LYS D 4 89  ? 153.334 127.768 115.760 1.00 34.72  ? 89  LYS B O   1 
ATOM 5223 C CB  . LYS D 4 89  ? 150.533 128.817 116.357 1.00 34.72  ? 89  LYS B CB  1 
ATOM 5224 C CG  . LYS D 4 89  ? 149.063 128.894 116.732 1.00 34.72  ? 89  LYS B CG  1 
ATOM 5225 C CD  . LYS D 4 89  ? 148.674 130.292 117.177 1.00 34.72  ? 89  LYS B CD  1 
ATOM 5226 C CE  . LYS D 4 89  ? 149.191 130.588 118.572 1.00 34.72  ? 89  LYS B CE  1 
ATOM 5227 N NZ  . LYS D 4 89  ? 148.536 129.734 119.600 1.00 34.72  ? 89  LYS B NZ  1 
ATOM 5228 N N   . VAL D 4 90  ? 152.317 127.459 113.773 1.00 33.53  ? 90  VAL B N   1 
ATOM 5229 C CA  . VAL D 4 90  ? 153.548 127.468 112.992 1.00 33.53  ? 90  VAL B CA  1 
ATOM 5230 C C   . VAL D 4 90  ? 153.842 128.851 112.429 1.00 33.53  ? 90  VAL B C   1 
ATOM 5231 O O   . VAL D 4 90  ? 154.972 129.334 112.509 1.00 33.53  ? 90  VAL B O   1 
ATOM 5232 C CB  . VAL D 4 90  ? 153.475 126.410 111.868 1.00 33.53  ? 90  VAL B CB  1 
ATOM 5233 C CG1 . VAL D 4 90  ? 154.748 126.429 111.038 1.00 33.53  ? 90  VAL B CG1 1 
ATOM 5234 C CG2 . VAL D 4 90  ? 153.235 125.030 112.456 1.00 33.53  ? 90  VAL B CG2 1 
ATOM 5235 N N   . HIS D 4 91  ? 152.835 129.507 111.856 1.00 31.84  ? 91  HIS B N   1 
ATOM 5236 C CA  . HIS D 4 91  ? 153.037 130.805 111.227 1.00 31.84  ? 91  HIS B CA  1 
ATOM 5237 C C   . HIS D 4 91  ? 151.915 131.757 111.610 1.00 31.84  ? 91  HIS B C   1 
ATOM 5238 O O   . HIS D 4 91  ? 150.772 131.343 111.814 1.00 31.84  ? 91  HIS B O   1 
ATOM 5239 C CB  . HIS D 4 91  ? 153.113 130.687 109.697 1.00 31.84  ? 91  HIS B CB  1 
ATOM 5240 C CG  . HIS D 4 91  ? 154.423 130.166 109.193 1.00 31.84  ? 91  HIS B CG  1 
ATOM 5241 N ND1 . HIS D 4 91  ? 154.542 128.958 108.541 1.00 31.84  ? 91  HIS B ND1 1 
ATOM 5242 C CD2 . HIS D 4 91  ? 155.669 130.692 109.242 1.00 31.84  ? 91  HIS B CD2 1 
ATOM 5243 C CE1 . HIS D 4 91  ? 155.806 128.761 108.211 1.00 31.84  ? 91  HIS B CE1 1 
ATOM 5244 N NE2 . HIS D 4 91  ? 156.511 129.798 108.625 1.00 31.84  ? 91  HIS B NE2 1 
ATOM 5245 N N   . ALA D 4 92  ? 152.252 133.043 111.685 1.00 33.46  ? 92  ALA B N   1 
ATOM 5246 C CA  . ALA D 4 92  ? 151.281 134.099 111.962 1.00 33.46  ? 92  ALA B CA  1 
ATOM 5247 C C   . ALA D 4 92  ? 151.597 135.278 111.052 1.00 33.46  ? 92  ALA B C   1 
ATOM 5248 O O   . ALA D 4 92  ? 152.581 135.990 111.276 1.00 33.46  ? 92  ALA B O   1 
ATOM 5249 C CB  . ALA D 4 92  ? 151.315 134.516 113.432 1.00 33.46  ? 92  ALA B CB  1 
ATOM 5250 N N   . ILE D 4 93  ? 150.770 135.482 110.036 1.00 35.29  ? 93  ILE B N   1 
ATOM 5251 C CA  . ILE D 4 93  ? 150.969 136.533 109.042 1.00 35.29  ? 93  ILE B CA  1 
ATOM 5252 C C   . ILE D 4 93  ? 150.078 137.711 109.413 1.00 35.29  ? 93  ILE B C   1 
ATOM 5253 O O   . ILE D 4 93  ? 148.845 137.560 109.423 1.00 35.29  ? 93  ILE B O   1 
ATOM 5254 C CB  . ILE D 4 93  ? 150.653 136.033 107.625 1.00 35.29  ? 93  ILE B CB  1 
ATOM 5255 C CG1 . ILE D 4 93  ? 151.607 134.905 107.230 1.00 35.29  ? 93  ILE B CG1 1 
ATOM 5256 C CG2 . ILE D 4 93  ? 150.741 137.176 106.627 1.00 35.29  ? 93  ILE B CG2 1 
ATOM 5257 C CD1 . ILE D 4 93  ? 151.204 134.184 105.964 1.00 35.29  ? 93  ILE B CD1 1 
ATOM 5258 N N   . PRO D 4 94  ? 150.638 138.880 109.732 1.00 37.63  ? 94  PRO B N   1 
ATOM 5259 C CA  . PRO D 4 94  ? 149.803 140.052 110.023 1.00 37.63  ? 94  PRO B CA  1 
ATOM 5260 C C   . PRO D 4 94  ? 149.247 140.700 108.764 1.00 37.63  ? 94  PRO B C   1 
ATOM 5261 O O   . PRO D 4 94  ? 149.842 141.643 108.232 1.00 37.63  ? 94  PRO B O   1 
ATOM 5262 C CB  . PRO D 4 94  ? 150.764 140.990 110.762 1.00 37.63  ? 94  PRO B CB  1 
ATOM 5263 C CG  . PRO D 4 94  ? 152.113 140.624 110.240 1.00 37.63  ? 94  PRO B CG  1 
ATOM 5264 C CD  . PRO D 4 94  ? 152.073 139.150 109.935 1.00 37.63  ? 94  PRO B CD  1 
ATOM 5265 N N   . LEU D 4 95  ? 148.117 140.191 108.274 1.00 40.26  ? 95  LEU B N   1 
ATOM 5266 C CA  . LEU D 4 95  ? 147.512 140.729 107.061 1.00 40.26  ? 95  LEU B CA  1 
ATOM 5267 C C   . LEU D 4 95  ? 147.175 142.206 107.229 1.00 40.26  ? 95  LEU B C   1 
ATOM 5268 O O   . LEU D 4 95  ? 146.690 142.636 108.279 1.00 40.26  ? 95  LEU B O   1 
ATOM 5269 C CB  . LEU D 4 95  ? 146.250 139.943 106.706 1.00 40.26  ? 95  LEU B CB  1 
ATOM 5270 C CG  . LEU D 4 95  ? 146.331 138.422 106.841 1.00 40.26  ? 95  LEU B CG  1 
ATOM 5271 C CD1 . LEU D 4 95  ? 144.940 137.810 106.826 1.00 40.26  ? 95  LEU B CD1 1 
ATOM 5272 C CD2 . LEU D 4 95  ? 147.191 137.834 105.735 1.00 40.26  ? 95  LEU B CD2 1 
ATOM 5273 N N   . ARG D 4 96  ? 147.440 142.985 106.177 1.00 44.68  ? 96  ARG B N   1 
ATOM 5274 C CA  . ARG D 4 96  ? 147.182 144.419 106.222 1.00 44.68  ? 96  ARG B CA  1 
ATOM 5275 C C   . ARG D 4 96  ? 145.697 144.749 106.148 1.00 44.68  ? 96  ARG B C   1 
ATOM 5276 O O   . ARG D 4 96  ? 145.313 145.883 106.451 1.00 44.68  ? 96  ARG B O   1 
ATOM 5277 C CB  . ARG D 4 96  ? 147.926 145.122 105.085 1.00 44.68  ? 96  ARG B CB  1 
ATOM 5278 N N   . SER D 4 97  ? 144.859 143.794 105.754 1.00 44.65  ? 97  SER B N   1 
ATOM 5279 C CA  . SER D 4 97  ? 143.419 143.998 105.647 1.00 44.65  ? 97  SER B CA  1 
ATOM 5280 C C   . SER D 4 97  ? 142.725 143.153 106.704 1.00 44.65  ? 97  SER B C   1 
ATOM 5281 O O   . SER D 4 97  ? 142.931 141.936 106.765 1.00 44.65  ? 97  SER B O   1 
ATOM 5282 C CB  . SER D 4 97  ? 142.914 143.637 104.249 1.00 44.65  ? 97  SER B CB  1 
ATOM 5283 O OG  . SER D 4 97  ? 141.513 143.824 104.150 1.00 44.65  ? 97  SER B OG  1 
ATOM 5284 N N   . SER D 4 98  ? 141.905 143.799 107.534 1.00 43.78  ? 98  SER B N   1 
ATOM 5285 C CA  . SER D 4 98  ? 141.178 143.091 108.580 1.00 43.78  ? 98  SER B CA  1 
ATOM 5286 C C   . SER D 4 98  ? 139.939 142.377 108.056 1.00 43.78  ? 98  SER B C   1 
ATOM 5287 O O   . SER D 4 98  ? 139.386 141.527 108.761 1.00 43.78  ? 98  SER B O   1 
ATOM 5288 C CB  . SER D 4 98  ? 140.778 144.062 109.692 1.00 43.78  ? 98  SER B CB  1 
ATOM 5289 O OG  . SER D 4 98  ? 140.008 143.412 110.688 1.00 43.78  ? 98  SER B OG  1 
ATOM 5290 N N   . TRP D 4 99  ? 139.494 142.701 106.844 1.00 44.98  ? 99  TRP B N   1 
ATOM 5291 C CA  . TRP D 4 99  ? 138.302 142.098 106.250 1.00 44.98  ? 99  TRP B CA  1 
ATOM 5292 C C   . TRP D 4 99  ? 138.758 140.978 105.322 1.00 44.98  ? 99  TRP B C   1 
ATOM 5293 O O   . TRP D 4 99  ? 139.093 141.205 104.159 1.00 44.98  ? 99  TRP B O   1 
ATOM 5294 C CB  . TRP D 4 99  ? 137.478 143.149 105.516 1.00 44.98  ? 99  TRP B CB  1 
ATOM 5295 C CG  . TRP D 4 99  ? 137.476 144.478 106.205 1.00 44.98  ? 99  TRP B CG  1 
ATOM 5296 C CD1 . TRP D 4 99  ? 138.149 145.601 105.821 1.00 44.98  ? 99  TRP B CD1 1 
ATOM 5297 C CD2 . TRP D 4 99  ? 136.776 144.821 107.406 1.00 44.98  ? 99  TRP B CD2 1 
ATOM 5298 N NE1 . TRP D 4 99  ? 137.907 146.623 106.706 1.00 44.98  ? 99  TRP B NE1 1 
ATOM 5299 C CE2 . TRP D 4 99  ? 137.068 146.170 107.689 1.00 44.98  ? 99  TRP B CE2 1 
ATOM 5300 C CE3 . TRP D 4 99  ? 135.929 144.119 108.269 1.00 44.98  ? 99  TRP B CE3 1 
ATOM 5301 C CZ2 . TRP D 4 99  ? 136.542 146.830 108.797 1.00 44.98  ? 99  TRP B CZ2 1 
ATOM 5302 C CZ3 . TRP D 4 99  ? 135.409 144.776 109.369 1.00 44.98  ? 99  TRP B CZ3 1 
ATOM 5303 C CH2 . TRP D 4 99  ? 135.718 146.118 109.623 1.00 44.98  ? 99  TRP B CH2 1 
ATOM 5304 N N   . VAL D 4 100 ? 138.771 139.755 105.847 1.00 39.77  ? 100 VAL B N   1 
ATOM 5305 C CA  . VAL D 4 100 ? 139.216 138.577 105.114 1.00 39.77  ? 100 VAL B CA  1 
ATOM 5306 C C   . VAL D 4 100 ? 138.064 137.585 105.051 1.00 39.77  ? 100 VAL B C   1 
ATOM 5307 O O   . VAL D 4 100 ? 137.468 137.252 106.081 1.00 39.77  ? 100 VAL B O   1 
ATOM 5308 C CB  . VAL D 4 100 ? 140.454 137.934 105.766 1.00 39.77  ? 100 VAL B CB  1 
ATOM 5309 C CG1 . VAL D 4 100 ? 141.032 136.859 104.861 1.00 39.77  ? 100 VAL B CG1 1 
ATOM 5310 C CG2 . VAL D 4 100 ? 141.499 138.993 106.081 1.00 39.77  ? 100 VAL B CG2 1 
ATOM 5311 N N   . MET D 4 101 ? 137.754 137.116 103.841 1.00 42.17  ? 101 MET B N   1 
ATOM 5312 C CA  . MET D 4 101 ? 136.701 136.135 103.630 1.00 42.17  ? 101 MET B CA  1 
ATOM 5313 C C   . MET D 4 101 ? 137.192 134.801 103.096 1.00 42.17  ? 101 MET B C   1 
ATOM 5314 O O   . MET D 4 101 ? 136.487 133.799 103.259 1.00 42.17  ? 101 MET B O   1 
ATOM 5315 C CB  . MET D 4 101 ? 135.640 136.678 102.660 1.00 42.17  ? 101 MET B CB  1 
ATOM 5316 C CG  . MET D 4 101 ? 134.831 137.840 103.198 1.00 42.17  ? 101 MET B CG  1 
ATOM 5317 S SD  . MET D 4 101 ? 133.620 138.418 101.996 1.00 42.17  ? 101 MET B SD  1 
ATOM 5318 C CE  . MET D 4 101 ? 132.922 139.810 102.874 1.00 42.17  ? 101 MET B CE  1 
ATOM 5319 N N   . THR D 4 102 ? 138.363 134.752 102.464 1.00 37.98  ? 102 THR B N   1 
ATOM 5320 C CA  . THR D 4 102 ? 138.862 133.522 101.872 1.00 37.98  ? 102 THR B CA  1 
ATOM 5321 C C   . THR D 4 102 ? 140.363 133.416 102.096 1.00 37.98  ? 102 THR B C   1 
ATOM 5322 O O   . THR D 4 102 ? 141.058 134.415 102.297 1.00 37.98  ? 102 THR B O   1 
ATOM 5323 C CB  . THR D 4 102 ? 138.550 133.446 100.371 1.00 37.98  ? 102 THR B CB  1 
ATOM 5324 O OG1 . THR D 4 102 ? 139.011 132.194 99.849  1.00 37.98  ? 102 THR B OG1 1 
ATOM 5325 C CG2 . THR D 4 102 ? 139.229 134.586 99.625  1.00 37.98  ? 102 THR B CG2 1 
ATOM 5326 N N   . CYS D 4 103 ? 140.853 132.179 102.065 1.00 32.68  ? 103 CYS B N   1 
ATOM 5327 C CA  . CYS D 4 103 ? 142.277 131.904 102.165 1.00 32.68  ? 103 CYS B CA  1 
ATOM 5328 C C   . CYS D 4 103 ? 142.568 130.581 101.476 1.00 32.68  ? 103 CYS B C   1 
ATOM 5329 O O   . CYS D 4 103 ? 141.712 129.693 101.420 1.00 32.68  ? 103 CYS B O   1 
ATOM 5330 C CB  . CYS D 4 103 ? 142.751 131.867 103.623 1.00 32.68  ? 103 CYS B CB  1 
ATOM 5331 S SG  . CYS D 4 103 ? 141.923 130.639 104.652 1.00 32.68  ? 103 CYS B SG  1 
ATOM 5332 N N   . ALA D 4 104 ? 143.784 130.456 100.952 1.00 32.64  ? 104 ALA B N   1 
ATOM 5333 C CA  . ALA D 4 104 ? 144.194 129.273 100.211 1.00 32.64  ? 104 ALA B CA  1 
ATOM 5334 C C   . ALA D 4 104 ? 145.569 128.819 100.673 1.00 32.64  ? 104 ALA B C   1 
ATOM 5335 O O   . ALA D 4 104 ? 146.359 129.597 101.214 1.00 32.64  ? 104 ALA B O   1 
ATOM 5336 C CB  . ALA D 4 104 ? 144.216 129.529 98.700  1.00 32.64  ? 104 ALA B CB  1 
ATOM 5337 N N   . TYR D 4 105 ? 145.843 127.536 100.450 1.00 34.89  ? 105 TYR B N   1 
ATOM 5338 C CA  . TYR D 4 105 ? 147.133 126.936 100.756 1.00 34.89  ? 105 TYR B CA  1 
ATOM 5339 C C   . TYR D 4 105 ? 147.639 126.246 99.499  1.00 34.89  ? 105 TYR B C   1 
ATOM 5340 O O   . TYR D 4 105 ? 146.905 125.471 98.878  1.00 34.89  ? 105 TYR B O   1 
ATOM 5341 C CB  . TYR D 4 105 ? 147.013 125.939 101.913 1.00 34.89  ? 105 TYR B CB  1 
ATOM 5342 C CG  . TYR D 4 105 ? 148.316 125.300 102.332 1.00 34.89  ? 105 TYR B CG  1 
ATOM 5343 C CD1 . TYR D 4 105 ? 149.248 126.006 103.081 1.00 34.89  ? 105 TYR B CD1 1 
ATOM 5344 C CD2 . TYR D 4 105 ? 148.615 123.991 101.981 1.00 34.89  ? 105 TYR B CD2 1 
ATOM 5345 C CE1 . TYR D 4 105 ? 150.439 125.426 103.473 1.00 34.89  ? 105 TYR B CE1 1 
ATOM 5346 C CE2 . TYR D 4 105 ? 149.805 123.402 102.367 1.00 34.89  ? 105 TYR B CE2 1 
ATOM 5347 C CZ  . TYR D 4 105 ? 150.712 124.124 103.113 1.00 34.89  ? 105 TYR B CZ  1 
ATOM 5348 O OH  . TYR D 4 105 ? 151.898 123.543 103.499 1.00 34.89  ? 105 TYR B OH  1 
ATOM 5349 N N   . ALA D 4 106 ? 148.881 126.533 99.121  1.00 37.23  ? 106 ALA B N   1 
ATOM 5350 C CA  . ALA D 4 106 ? 149.420 125.995 97.880  1.00 37.23  ? 106 ALA B CA  1 
ATOM 5351 C C   . ALA D 4 106 ? 149.541 124.475 97.968  1.00 37.23  ? 106 ALA B C   1 
ATOM 5352 O O   . ALA D 4 106 ? 149.860 123.937 99.033  1.00 37.23  ? 106 ALA B O   1 
ATOM 5353 C CB  . ALA D 4 106 ? 150.783 126.609 97.572  1.00 37.23  ? 106 ALA B CB  1 
ATOM 5354 N N   . PRO D 4 107 ? 149.282 123.757 96.871  1.00 37.84  ? 107 PRO B N   1 
ATOM 5355 C CA  . PRO D 4 107 ? 149.437 122.293 96.902  1.00 37.84  ? 107 PRO B CA  1 
ATOM 5356 C C   . PRO D 4 107 ? 150.845 121.846 97.249  1.00 37.84  ? 107 PRO B C   1 
ATOM 5357 O O   . PRO D 4 107 ? 151.013 120.807 97.900  1.00 37.84  ? 107 PRO B O   1 
ATOM 5358 C CB  . PRO D 4 107 ? 149.042 121.869 95.481  1.00 37.84  ? 107 PRO B CB  1 
ATOM 5359 C CG  . PRO D 4 107 ? 148.210 122.998 94.958  1.00 37.84  ? 107 PRO B CG  1 
ATOM 5360 C CD  . PRO D 4 107 ? 148.784 124.236 95.571  1.00 37.84  ? 107 PRO B CD  1 
ATOM 5361 N N   . SER D 4 108 ? 151.864 122.598 96.834  1.00 39.12  ? 108 SER B N   1 
ATOM 5362 C CA  . SER D 4 108 ? 153.239 122.284 97.198  1.00 39.12  ? 108 SER B CA  1 
ATOM 5363 C C   . SER D 4 108 ? 153.615 122.801 98.580  1.00 39.12  ? 108 SER B C   1 
ATOM 5364 O O   . SER D 4 108 ? 154.685 122.444 99.086  1.00 39.12  ? 108 SER B O   1 
ATOM 5365 C CB  . SER D 4 108 ? 154.202 122.855 96.154  1.00 39.12  ? 108 SER B CB  1 
ATOM 5366 O OG  . SER D 4 108 ? 154.184 124.270 96.165  1.00 39.12  ? 108 SER B OG  1 
ATOM 5367 N N   . GLY D 4 109 ? 152.771 123.624 99.197  1.00 38.24  ? 109 GLY B N   1 
ATOM 5368 C CA  . GLY D 4 109 ? 153.002 124.087 100.548 1.00 38.24  ? 109 GLY B CA  1 
ATOM 5369 C C   . GLY D 4 109 ? 153.935 125.266 100.690 1.00 38.24  ? 109 GLY B C   1 
ATOM 5370 O O   . GLY D 4 109 ? 154.257 125.644 101.823 1.00 38.24  ? 109 GLY B O   1 
ATOM 5371 N N   . ASN D 4 110 ? 154.382 125.863 99.588  1.00 41.51  ? 110 ASN B N   1 
ATOM 5372 C CA  . ASN D 4 110 ? 155.300 126.992 99.638  1.00 41.51  ? 110 ASN B CA  1 
ATOM 5373 C C   . ASN D 4 110 ? 154.602 128.340 99.518  1.00 41.51  ? 110 ASN B C   1 
ATOM 5374 O O   . ASN D 4 110 ? 155.281 129.371 99.494  1.00 41.51  ? 110 ASN B O   1 
ATOM 5375 C CB  . ASN D 4 110 ? 156.358 126.862 98.538  1.00 41.51  ? 110 ASN B CB  1 
ATOM 5376 C CG  . ASN D 4 110 ? 155.750 126.654 97.166  1.00 41.51  ? 110 ASN B CG  1 
ATOM 5377 O OD1 . ASN D 4 110 ? 154.545 126.441 97.034  1.00 41.51  ? 110 ASN B OD1 1 
ATOM 5378 N ND2 . ASN D 4 110 ? 156.584 126.716 96.134  1.00 41.51  ? 110 ASN B ND2 1 
ATOM 5379 N N   . TYR D 4 111 ? 153.272 128.364 99.445  1.00 39.48  ? 111 TYR B N   1 
ATOM 5380 C CA  . TYR D 4 111 ? 152.549 129.617 99.287  1.00 39.48  ? 111 TYR B CA  1 
ATOM 5381 C C   . TYR D 4 111 ? 151.216 129.542 100.014 1.00 39.48  ? 111 TYR B C   1 
ATOM 5382 O O   . TYR D 4 111 ? 150.649 128.462 100.202 1.00 39.48  ? 111 TYR B O   1 
ATOM 5383 C CB  . TYR D 4 111 ? 152.315 129.952 97.808  1.00 39.48  ? 111 TYR B CB  1 
ATOM 5384 C CG  . TYR D 4 111 ? 153.566 130.346 97.055  1.00 39.48  ? 111 TYR B CG  1 
ATOM 5385 C CD1 . TYR D 4 111 ? 154.165 131.581 97.265  1.00 39.48  ? 111 TYR B CD1 1 
ATOM 5386 C CD2 . TYR D 4 111 ? 154.144 129.485 96.133  1.00 39.48  ? 111 TYR B CD2 1 
ATOM 5387 C CE1 . TYR D 4 111 ? 155.307 131.946 96.577  1.00 39.48  ? 111 TYR B CE1 1 
ATOM 5388 C CE2 . TYR D 4 111 ? 155.287 129.841 95.441  1.00 39.48  ? 111 TYR B CE2 1 
ATOM 5389 C CZ  . TYR D 4 111 ? 155.864 131.072 95.668  1.00 39.48  ? 111 TYR B CZ  1 
ATOM 5390 O OH  . TYR D 4 111 ? 157.001 131.432 94.982  1.00 39.48  ? 111 TYR B OH  1 
ATOM 5391 N N   . VAL D 4 112 ? 150.727 130.711 100.427 1.00 36.75  ? 112 VAL B N   1 
ATOM 5392 C CA  . VAL D 4 112 ? 149.397 130.867 101.000 1.00 36.75  ? 112 VAL B CA  1 
ATOM 5393 C C   . VAL D 4 112 ? 148.748 132.085 100.359 1.00 36.75  ? 112 VAL B C   1 
ATOM 5394 O O   . VAL D 4 112 ? 149.421 132.964 99.820  1.00 36.75  ? 112 VAL B O   1 
ATOM 5395 C CB  . VAL D 4 112 ? 149.422 131.014 102.537 1.00 36.75  ? 112 VAL B CB  1 
ATOM 5396 C CG1 . VAL D 4 112 ? 149.802 129.696 103.194 1.00 36.75  ? 112 VAL B CG1 1 
ATOM 5397 C CG2 . VAL D 4 112 ? 150.379 132.119 102.948 1.00 36.75  ? 112 VAL B CG2 1 
ATOM 5398 N N   . ALA D 4 113 ? 147.420 132.132 100.426 1.00 35.88  ? 113 ALA B N   1 
ATOM 5399 C CA  . ALA D 4 113 ? 146.654 133.208 99.816  1.00 35.88  ? 113 ALA B CA  1 
ATOM 5400 C C   . ALA D 4 113 ? 145.610 133.728 100.793 1.00 35.88  ? 113 ALA B C   1 
ATOM 5401 O O   . ALA D 4 113 ? 145.202 133.037 101.729 1.00 35.88  ? 113 ALA B O   1 
ATOM 5402 C CB  . ALA D 4 113 ? 145.973 132.753 98.518  1.00 35.88  ? 113 ALA B CB  1 
ATOM 5403 N N   . CYS D 4 114 ? 145.194 134.972 100.566 1.00 40.08  ? 114 CYS B N   1 
ATOM 5404 C CA  . CYS D 4 114 ? 144.147 135.594 101.363 1.00 40.08  ? 114 CYS B CA  1 
ATOM 5405 C C   . CYS D 4 114 ? 143.460 136.662 100.524 1.00 40.08  ? 114 CYS B C   1 
ATOM 5406 O O   . CYS D 4 114 ? 144.000 137.133 99.521  1.00 40.08  ? 114 CYS B O   1 
ATOM 5407 C CB  . CYS D 4 114 ? 144.703 136.201 102.657 1.00 40.08  ? 114 CYS B CB  1 
ATOM 5408 S SG  . CYS D 4 114 ? 145.652 137.720 102.421 1.00 40.08  ? 114 CYS B SG  1 
ATOM 5409 N N   . GLY D 4 115 ? 142.259 137.037 100.944 1.00 40.51  ? 115 GLY B N   1 
ATOM 5410 C CA  . GLY D 4 115 ? 141.508 138.061 100.237 1.00 40.51  ? 115 GLY B CA  1 
ATOM 5411 C C   . GLY D 4 115 ? 140.230 138.382 100.978 1.00 40.51  ? 115 GLY B C   1 
ATOM 5412 O O   . GLY D 4 115 ? 139.830 137.681 101.913 1.00 40.51  ? 115 GLY B O   1 
ATOM 5413 N N   . GLY D 4 116 ? 139.586 139.461 100.539 1.00 43.03  ? 116 GLY B N   1 
ATOM 5414 C CA  . GLY D 4 116 ? 138.354 139.903 101.162 1.00 43.03  ? 116 GLY B CA  1 
ATOM 5415 C C   . GLY D 4 116 ? 137.825 141.210 100.608 1.00 43.03  ? 116 GLY B C   1 
ATOM 5416 O O   . GLY D 4 116 ? 137.764 141.396 99.389  1.00 43.03  ? 116 GLY B O   1 
ATOM 5417 N N   . LEU D 4 117 ? 137.438 142.125 101.497 1.00 47.33  ? 117 LEU B N   1 
ATOM 5418 C CA  . LEU D 4 117 ? 136.906 143.419 101.086 1.00 47.33  ? 117 LEU B CA  1 
ATOM 5419 C C   . LEU D 4 117 ? 138.024 144.395 100.742 1.00 47.33  ? 117 LEU B C   1 
ATOM 5420 O O   . LEU D 4 117 ? 138.075 145.506 101.279 1.00 47.33  ? 117 LEU B O   1 
ATOM 5421 C CB  . LEU D 4 117 ? 136.018 144.007 102.184 1.00 47.33  ? 117 LEU B CB  1 
ATOM 5422 C CG  . LEU D 4 117 ? 134.826 143.171 102.646 1.00 47.33  ? 117 LEU B CG  1 
ATOM 5423 C CD1 . LEU D 4 117 ? 134.163 143.809 103.853 1.00 47.33  ? 117 LEU B CD1 1 
ATOM 5424 C CD2 . LEU D 4 117 ? 133.834 143.028 101.510 1.00 47.33  ? 117 LEU B CD2 1 
ATOM 5425 N N   . ASP D 4 118 ? 138.923 143.989 99.848  1.00 48.48  ? 118 ASP B N   1 
ATOM 5426 C CA  . ASP D 4 118 ? 140.001 144.859 99.403  1.00 48.48  ? 118 ASP B CA  1 
ATOM 5427 C C   . ASP D 4 118 ? 140.237 144.801 97.901  1.00 48.48  ? 118 ASP B C   1 
ATOM 5428 O O   . ASP D 4 118 ? 141.123 145.509 97.411  1.00 48.48  ? 118 ASP B O   1 
ATOM 5429 C CB  . ASP D 4 118 ? 141.307 144.512 100.138 1.00 48.48  ? 118 ASP B CB  1 
ATOM 5430 C CG  . ASP D 4 118 ? 141.648 143.036 100.058 1.00 48.48  ? 118 ASP B CG  1 
ATOM 5431 O OD1 . ASP D 4 118 ? 140.826 142.261 99.527  1.00 48.48  ? 118 ASP B OD1 1 
ATOM 5432 O OD2 . ASP D 4 118 ? 142.740 142.651 100.527 1.00 48.48  ? 118 ASP B OD2 1 
ATOM 5433 N N   . ASN D 4 119 ? 139.487 143.981 97.163  1.00 49.86  ? 119 ASN B N   1 
ATOM 5434 C CA  . ASN D 4 119 ? 139.622 143.821 95.716  1.00 49.86  ? 119 ASN B CA  1 
ATOM 5435 C C   . ASN D 4 119 ? 141.006 143.320 95.312  1.00 49.86  ? 119 ASN B C   1 
ATOM 5436 O O   . ASN D 4 119 ? 141.390 143.425 94.143  1.00 49.86  ? 119 ASN B O   1 
ATOM 5437 C CB  . ASN D 4 119 ? 139.294 145.123 94.976  1.00 49.86  ? 119 ASN B CB  1 
ATOM 5438 C CG  . ASN D 4 119 ? 137.915 145.653 95.315  1.00 49.86  ? 119 ASN B CG  1 
ATOM 5439 O OD1 . ASN D 4 119 ? 137.009 144.890 95.647  1.00 49.86  ? 119 ASN B OD1 1 
ATOM 5440 N ND2 . ASN D 4 119 ? 137.748 146.967 95.225  1.00 49.86  ? 119 ASN B ND2 1 
ATOM 5441 N N   . ILE D 4 120 ? 141.764 142.774 96.261  1.00 46.53  ? 120 ILE B N   1 
ATOM 5442 C CA  . ILE D 4 120 ? 143.111 142.272 96.012  1.00 46.53  ? 120 ILE B CA  1 
ATOM 5443 C C   . ILE D 4 120 ? 143.254 140.916 96.689  1.00 46.53  ? 120 ILE B C   1 
ATOM 5444 O O   . ILE D 4 120 ? 142.875 140.757 97.854  1.00 46.53  ? 120 ILE B O   1 
ATOM 5445 C CB  . ILE D 4 120 ? 144.193 143.242 96.530  1.00 46.53  ? 120 ILE B CB  1 
ATOM 5446 C CG1 . ILE D 4 120 ? 144.010 144.636 95.926  1.00 46.53  ? 120 ILE B CG1 1 
ATOM 5447 C CG2 . ILE D 4 120 ? 145.584 142.706 96.226  1.00 46.53  ? 120 ILE B CG2 1 
ATOM 5448 C CD1 . ILE D 4 120 ? 145.075 145.627 96.343  1.00 46.53  ? 120 ILE B CD1 1 
ATOM 5449 N N   . CYS D 4 121 ? 143.798 139.942 95.963  1.00 45.76  ? 121 CYS B N   1 
ATOM 5450 C CA  . CYS D 4 121 ? 144.189 138.664 96.546  1.00 45.76  ? 121 CYS B CA  1 
ATOM 5451 C C   . CYS D 4 121 ? 145.690 138.702 96.807  1.00 45.76  ? 121 CYS B C   1 
ATOM 5452 O O   . CYS D 4 121 ? 146.483 138.908 95.881  1.00 45.76  ? 121 CYS B O   1 
ATOM 5453 C CB  . CYS D 4 121 ? 143.817 137.490 95.636  1.00 45.76  ? 121 CYS B CB  1 
ATOM 5454 S SG  . CYS D 4 121 ? 143.835 135.857 96.458  1.00 45.76  ? 121 CYS B SG  1 
ATOM 5455 N N   . SER D 4 122 ? 146.074 138.519 98.066  1.00 42.59  ? 122 SER B N   1 
ATOM 5456 C CA  . SER D 4 122 ? 147.465 138.605 98.487  1.00 42.59  ? 122 SER B CA  1 
ATOM 5457 C C   . SER D 4 122 ? 148.034 137.205 98.663  1.00 42.59  ? 122 SER B C   1 
ATOM 5458 O O   . SER D 4 122 ? 147.418 136.355 99.314  1.00 42.59  ? 122 SER B O   1 
ATOM 5459 C CB  . SER D 4 122 ? 147.594 139.397 99.789  1.00 42.59  ? 122 SER B CB  1 
ATOM 5460 O OG  . SER D 4 122 ? 146.878 140.618 99.715  1.00 42.59  ? 122 SER B OG  1 
ATOM 5461 N N   . ILE D 4 123 ? 149.211 136.974 98.087  1.00 40.31  ? 123 ILE B N   1 
ATOM 5462 C CA  . ILE D 4 123 ? 149.881 135.682 98.123  1.00 40.31  ? 123 ILE B CA  1 
ATOM 5463 C C   . ILE D 4 123 ? 151.214 135.852 98.836  1.00 40.31  ? 123 ILE B C   1 
ATOM 5464 O O   . ILE D 4 123 ? 152.027 136.703 98.451  1.00 40.31  ? 123 ILE B O   1 
ATOM 5465 C CB  . ILE D 4 123 ? 150.085 135.110 96.708  1.00 40.31  ? 123 ILE B CB  1 
ATOM 5466 C CG1 . ILE D 4 123 ? 148.732 134.826 96.056  1.00 40.31  ? 123 ILE B CG1 1 
ATOM 5467 C CG2 . ILE D 4 123 ? 150.940 133.853 96.756  1.00 40.31  ? 123 ILE B CG2 1 
ATOM 5468 C CD1 . ILE D 4 123 ? 148.812 134.588 94.573  1.00 40.31  ? 123 ILE B CD1 1 
ATOM 5469 N N   . TYR D 4 124 ? 151.434 135.030 99.859  1.00 39.77  ? 124 TYR B N   1 
ATOM 5470 C CA  . TYR D 4 124 ? 152.631 135.051 100.683 1.00 39.77  ? 124 TYR B CA  1 
ATOM 5471 C C   . TYR D 4 124 ? 153.407 133.758 100.480 1.00 39.77  ? 124 TYR B C   1 
ATOM 5472 O O   . TYR D 4 124 ? 152.823 132.706 100.202 1.00 39.77  ? 124 TYR B O   1 
ATOM 5473 C CB  . TYR D 4 124 ? 152.277 135.198 102.170 1.00 39.77  ? 124 TYR B CB  1 
ATOM 5474 C CG  . TYR D 4 124 ? 151.610 136.503 102.536 1.00 39.77  ? 124 TYR B CG  1 
ATOM 5475 C CD1 . TYR D 4 124 ? 152.356 137.651 102.756 1.00 39.77  ? 124 TYR B CD1 1 
ATOM 5476 C CD2 . TYR D 4 124 ? 150.230 136.585 102.663 1.00 39.77  ? 124 TYR B CD2 1 
ATOM 5477 C CE1 . TYR D 4 124 ? 151.748 138.845 103.092 1.00 39.77  ? 124 TYR B CE1 1 
ATOM 5478 C CE2 . TYR D 4 124 ? 149.612 137.774 102.997 1.00 39.77  ? 124 TYR B CE2 1 
ATOM 5479 C CZ  . TYR D 4 124 ? 150.375 138.900 103.211 1.00 39.77  ? 124 TYR B CZ  1 
ATOM 5480 O OH  . TYR D 4 124 ? 149.764 140.087 103.545 1.00 39.77  ? 124 TYR B OH  1 
ATOM 5481 N N   . ASN D 4 125 ? 154.727 133.836 100.626 1.00 43.69  ? 125 ASN B N   1 
ATOM 5482 C CA  . ASN D 4 125 ? 155.587 132.662 100.556 1.00 43.69  ? 125 ASN B CA  1 
ATOM 5483 C C   . ASN D 4 125 ? 156.051 132.289 101.958 1.00 43.69  ? 125 ASN B C   1 
ATOM 5484 O O   . ASN D 4 125 ? 156.495 133.152 102.722 1.00 43.69  ? 125 ASN B O   1 
ATOM 5485 C CB  . ASN D 4 125 ? 156.790 132.901 99.640  1.00 43.69  ? 125 ASN B CB  1 
ATOM 5486 C CG  . ASN D 4 125 ? 157.491 134.215 99.918  1.00 43.69  ? 125 ASN B CG  1 
ATOM 5487 O OD1 . ASN D 4 125 ? 157.067 134.991 100.771 1.00 43.69  ? 125 ASN B OD1 1 
ATOM 5488 N ND2 . ASN D 4 125 ? 158.576 134.470 99.195  1.00 43.69  ? 125 ASN B ND2 1 
ATOM 5489 N N   . LEU D 4 126 ? 155.938 131.004 102.294 1.00 44.04  ? 126 LEU B N   1 
ATOM 5490 C CA  . LEU D 4 126 ? 156.289 130.547 103.634 1.00 44.04  ? 126 LEU B CA  1 
ATOM 5491 C C   . LEU D 4 126 ? 157.795 130.355 103.776 1.00 44.04  ? 126 LEU B C   1 
ATOM 5492 O O   . LEU D 4 126 ? 158.435 130.981 104.627 1.00 44.04  ? 126 LEU B O   1 
ATOM 5493 C CB  . LEU D 4 126 ? 155.543 129.250 103.956 1.00 44.04  ? 126 LEU B CB  1 
ATOM 5494 C CG  . LEU D 4 126 ? 154.042 129.268 103.664 1.00 44.04  ? 126 LEU B CG  1 
ATOM 5495 C CD1 . LEU D 4 126 ? 153.387 127.968 104.103 1.00 44.04  ? 126 LEU B CD1 1 
ATOM 5496 C CD2 . LEU D 4 126 ? 153.383 130.462 104.334 1.00 44.04  ? 126 LEU B CD2 1 
ATOM 5497 N N   . LYS D 4 127 ? 158.374 129.491 102.950 1.00 57.96  ? 127 LYS B N   1 
ATOM 5498 C CA  . LYS D 4 127 ? 159.804 129.216 102.966 1.00 57.96  ? 127 LYS B CA  1 
ATOM 5499 C C   . LYS D 4 127 ? 160.442 129.778 101.704 1.00 57.96  ? 127 LYS B C   1 
ATOM 5500 O O   . LYS D 4 127 ? 159.861 129.694 100.616 1.00 57.96  ? 127 LYS B O   1 
ATOM 5501 C CB  . LYS D 4 127 ? 160.072 127.713 103.090 1.00 57.96  ? 127 LYS B CB  1 
ATOM 5502 C CG  . LYS D 4 127 ? 159.610 126.881 101.903 1.00 57.96  ? 127 LYS B CG  1 
ATOM 5503 C CD  . LYS D 4 127 ? 159.950 125.412 102.093 1.00 57.96  ? 127 LYS B CD  1 
ATOM 5504 C CE  . LYS D 4 127 ? 159.065 124.774 103.152 1.00 57.96  ? 127 LYS B CE  1 
ATOM 5505 N NZ  . LYS D 4 127 ? 157.639 124.722 102.728 1.00 57.96  ? 127 LYS B NZ  1 
ATOM 5506 N N   . THR D 4 128 ? 161.623 130.369 101.856 1.00 69.88  ? 128 THR B N   1 
ATOM 5507 C CA  . THR D 4 128 ? 162.336 130.957 100.728 1.00 69.88  ? 128 THR B CA  1 
ATOM 5508 C C   . THR D 4 128 ? 163.782 130.475 100.682 1.00 69.88  ? 128 THR B C   1 
ATOM 5509 O O   . THR D 4 128 ? 164.275 130.062 99.632  1.00 69.88  ? 128 THR B O   1 
ATOM 5510 C CB  . THR D 4 128 ? 162.318 132.496 100.790 1.00 69.88  ? 128 THR B CB  1 
ATOM 5511 O OG1 . THR D 4 128 ? 163.032 133.030 99.668  1.00 69.88  ? 128 THR B OG1 1 
ATOM 5512 C CG2 . THR D 4 128 ? 162.963 132.985 102.077 1.00 69.88  ? 128 THR B CG2 1 
ATOM 5513 N N   . VAL D 4 133 ? 158.016 135.362 106.975 1.00 43.48  ? 133 VAL B N   1 
ATOM 5514 C CA  . VAL D 4 133 ? 157.082 135.418 105.858 1.00 43.48  ? 133 VAL B CA  1 
ATOM 5515 C C   . VAL D 4 133 ? 156.993 136.844 105.325 1.00 43.48  ? 133 VAL B C   1 
ATOM 5516 O O   . VAL D 4 133 ? 156.837 137.795 106.091 1.00 43.48  ? 133 VAL B O   1 
ATOM 5517 C CB  . VAL D 4 133 ? 155.693 134.894 106.268 1.00 43.48  ? 133 VAL B CB  1 
ATOM 5518 C CG1 . VAL D 4 133 ? 154.692 135.093 105.141 1.00 43.48  ? 133 VAL B CG1 1 
ATOM 5519 C CG2 . VAL D 4 133 ? 155.775 133.428 106.664 1.00 43.48  ? 133 VAL B CG2 1 
ATOM 5520 N N   . ARG D 4 134 ? 157.093 136.984 104.005 1.00 47.64  ? 134 ARG B N   1 
ATOM 5521 C CA  . ARG D 4 134 ? 157.056 138.278 103.343 1.00 47.64  ? 134 ARG B CA  1 
ATOM 5522 C C   . ARG D 4 134 ? 156.036 138.229 102.215 1.00 47.64  ? 134 ARG B C   1 
ATOM 5523 O O   . ARG D 4 134 ? 155.718 137.157 101.694 1.00 47.64  ? 134 ARG B O   1 
ATOM 5524 C CB  . ARG D 4 134 ? 158.447 138.661 102.800 1.00 47.64  ? 134 ARG B CB  1 
ATOM 5525 C CG  . ARG D 4 134 ? 158.563 140.066 102.214 1.00 47.64  ? 134 ARG B CG  1 
ATOM 5526 C CD  . ARG D 4 134 ? 158.738 141.127 103.295 1.00 47.64  ? 134 ARG B CD  1 
ATOM 5527 N NE  . ARG D 4 134 ? 157.503 141.396 104.022 1.00 47.64  ? 134 ARG B NE  1 
ATOM 5528 C CZ  . ARG D 4 134 ? 157.327 142.418 104.848 1.00 47.64  ? 134 ARG B CZ  1 
ATOM 5529 N NH1 . ARG D 4 134 ? 158.292 143.292 105.081 1.00 47.64  ? 134 ARG B NH1 1 
ATOM 5530 N NH2 . ARG D 4 134 ? 156.153 142.567 105.456 1.00 47.64  ? 134 ARG B NH2 1 
ATOM 5531 N N   . VAL D 4 135 ? 155.507 139.398 101.853 1.00 45.87  ? 135 VAL B N   1 
ATOM 5532 C CA  . VAL D 4 135 ? 154.538 139.469 100.767 1.00 45.87  ? 135 VAL B CA  1 
ATOM 5533 C C   . VAL D 4 135 ? 155.222 139.110 99.454  1.00 45.87  ? 135 VAL B C   1 
ATOM 5534 O O   . VAL D 4 135 ? 156.322 139.590 99.150  1.00 45.87  ? 135 VAL B O   1 
ATOM 5535 C CB  . VAL D 4 135 ? 153.879 140.857 100.716 1.00 45.87  ? 135 VAL B CB  1 
ATOM 5536 C CG1 . VAL D 4 135 ? 154.896 141.947 100.395 1.00 45.87  ? 135 VAL B CG1 1 
ATOM 5537 C CG2 . VAL D 4 135 ? 152.741 140.867 99.706  1.00 45.87  ? 135 VAL B CG2 1 
ATOM 5538 N N   . SER D 4 136 ? 154.589 138.226 98.684  1.00 44.77  ? 136 SER B N   1 
ATOM 5539 C CA  . SER D 4 136 ? 155.134 137.792 97.405  1.00 44.77  ? 136 SER B CA  1 
ATOM 5540 C C   . SER D 4 136 ? 154.362 138.330 96.211  1.00 44.77  ? 136 SER B C   1 
ATOM 5541 O O   . SER D 4 136 ? 154.973 138.631 95.181  1.00 44.77  ? 136 SER B O   1 
ATOM 5542 C CB  . SER D 4 136 ? 155.167 136.262 97.330  1.00 44.77  ? 136 SER B CB  1 
ATOM 5543 O OG  . SER D 4 136 ? 153.858 135.721 97.338  1.00 44.77  ? 136 SER B OG  1 
ATOM 5544 N N   . ARG D 4 137 ? 153.042 138.460 96.319  1.00 48.36  ? 137 ARG B N   1 
ATOM 5545 C CA  . ARG D 4 137 ? 152.259 138.975 95.205  1.00 48.36  ? 137 ARG B CA  1 
ATOM 5546 C C   . ARG D 4 137 ? 150.981 139.607 95.737  1.00 48.36  ? 137 ARG B C   1 
ATOM 5547 O O   . ARG D 4 137 ? 150.457 139.198 96.774  1.00 48.36  ? 137 ARG B O   1 
ATOM 5548 C CB  . ARG D 4 137 ? 151.935 137.865 94.196  1.00 48.36  ? 137 ARG B CB  1 
ATOM 5549 C CG  . ARG D 4 137 ? 151.315 138.353 92.896  1.00 48.36  ? 137 ARG B CG  1 
ATOM 5550 C CD  . ARG D 4 137 ? 152.244 139.304 92.160  1.00 48.36  ? 137 ARG B CD  1 
ATOM 5551 N NE  . ARG D 4 137 ? 153.456 138.639 91.695  1.00 48.36  ? 137 ARG B NE  1 
ATOM 5552 C CZ  . ARG D 4 137 ? 154.469 139.259 91.105  1.00 48.36  ? 137 ARG B CZ  1 
ATOM 5553 N NH1 . ARG D 4 137 ? 154.451 140.564 90.890  1.00 48.36  ? 137 ARG B NH1 1 
ATOM 5554 N NH2 . ARG D 4 137 ? 155.528 138.550 90.721  1.00 48.36  ? 137 ARG B NH2 1 
ATOM 5555 N N   . GLU D 4 138 ? 150.490 140.612 95.014  1.00 46.76  ? 138 GLU B N   1 
ATOM 5556 C CA  . GLU D 4 138 ? 149.221 141.272 95.323  1.00 46.76  ? 138 GLU B CA  1 
ATOM 5557 C C   . GLU D 4 138 ? 148.455 141.432 94.014  1.00 46.76  ? 138 GLU B C   1 
ATOM 5558 O O   . GLU D 4 138 ? 148.635 142.424 93.302  1.00 46.76  ? 138 GLU B O   1 
ATOM 5559 C CB  . GLU D 4 138 ? 149.444 142.619 96.005  1.00 46.76  ? 138 GLU B CB  1 
ATOM 5560 C CG  . GLU D 4 138 ? 150.228 142.545 97.305  1.00 46.76  ? 138 GLU B CG  1 
ATOM 5561 C CD  . GLU D 4 138 ? 149.960 143.729 98.213  1.00 46.76  ? 138 GLU B CD  1 
ATOM 5562 O OE1 . GLU D 4 138 ? 150.109 144.879 97.751  1.00 46.76  ? 138 GLU B OE1 1 
ATOM 5563 O OE2 . GLU D 4 138 ? 149.602 143.508 99.389  1.00 46.76  ? 138 GLU B OE2 1 
ATOM 5564 N N   . LEU D 4 139 ? 147.605 140.459 93.696  1.00 42.85  ? 139 LEU B N   1 
ATOM 5565 C CA  . LEU D 4 139 ? 146.859 140.461 92.445  1.00 42.85  ? 139 LEU B CA  1 
ATOM 5566 C C   . LEU D 4 139 ? 145.619 141.333 92.595  1.00 42.85  ? 139 LEU B C   1 
ATOM 5567 O O   . LEU D 4 139 ? 144.775 141.079 93.462  1.00 42.85  ? 139 LEU B O   1 
ATOM 5568 C CB  . LEU D 4 139 ? 146.475 139.037 92.049  1.00 42.85  ? 139 LEU B CB  1 
ATOM 5569 C CG  . LEU D 4 139 ? 147.641 138.055 91.935  1.00 42.85  ? 139 LEU B CG  1 
ATOM 5570 C CD1 . LEU D 4 139 ? 147.139 136.630 92.029  1.00 42.85  ? 139 LEU B CD1 1 
ATOM 5571 C CD2 . LEU D 4 139 ? 148.401 138.273 90.637  1.00 42.85  ? 139 LEU B CD2 1 
ATOM 5572 N N   . ALA D 4 140 ? 145.510 142.351 91.745  1.00 46.40  ? 140 ALA B N   1 
ATOM 5573 C CA  . ALA D 4 140 ? 144.400 143.289 91.767  1.00 46.40  ? 140 ALA B CA  1 
ATOM 5574 C C   . ALA D 4 140 ? 143.852 143.463 90.358  1.00 46.40  ? 140 ALA B C   1 
ATOM 5575 O O   . ALA D 4 140 ? 144.532 143.189 89.365  1.00 46.40  ? 140 ALA B O   1 
ATOM 5576 C CB  . ALA D 4 140 ? 144.821 144.650 92.340  1.00 46.40  ? 140 ALA B CB  1 
ATOM 5577 N N   . GLY D 4 141 ? 142.610 143.931 90.282  1.00 48.68  ? 141 GLY B N   1 
ATOM 5578 C CA  . GLY D 4 141 ? 141.944 144.102 89.006  1.00 48.68  ? 141 GLY B CA  1 
ATOM 5579 C C   . GLY D 4 141 ? 140.461 143.801 89.072  1.00 48.68  ? 141 GLY B C   1 
ATOM 5580 O O   . GLY D 4 141 ? 139.727 144.036 88.107  1.00 48.68  ? 141 GLY B O   1 
ATOM 5581 N N   . HIS D 4 142 ? 140.011 143.278 90.208  1.00 46.43  ? 142 HIS B N   1 
ATOM 5582 C CA  . HIS D 4 142 ? 138.599 143.003 90.428  1.00 46.43  ? 142 HIS B CA  1 
ATOM 5583 C C   . HIS D 4 142 ? 137.915 144.230 91.016  1.00 46.43  ? 142 HIS B C   1 
ATOM 5584 O O   . HIS D 4 142 ? 138.468 144.908 91.886  1.00 46.43  ? 142 HIS B O   1 
ATOM 5585 C CB  . HIS D 4 142 ? 138.423 141.806 91.364  1.00 46.43  ? 142 HIS B CB  1 
ATOM 5586 C CG  . HIS D 4 142 ? 138.382 140.487 90.657  1.00 46.43  ? 142 HIS B CG  1 
ATOM 5587 N ND1 . HIS D 4 142 ? 138.628 139.291 91.297  1.00 46.43  ? 142 HIS B ND1 1 
ATOM 5588 C CD2 . HIS D 4 142 ? 138.119 140.174 89.366  1.00 46.43  ? 142 HIS B CD2 1 
ATOM 5589 C CE1 . HIS D 4 142 ? 138.521 138.300 90.431  1.00 46.43  ? 142 HIS B CE1 1 
ATOM 5590 N NE2 . HIS D 4 142 ? 138.212 138.808 89.252  1.00 46.43  ? 142 HIS B NE2 1 
ATOM 5591 N N   . THR D 4 143 ? 136.709 144.513 90.530  1.00 50.49  ? 143 THR B N   1 
ATOM 5592 C CA  . THR D 4 143 ? 135.928 145.646 91.009  1.00 50.49  ? 143 THR B CA  1 
ATOM 5593 C C   . THR D 4 143 ? 135.003 145.282 92.162  1.00 50.49  ? 143 THR B C   1 
ATOM 5594 O O   . THR D 4 143 ? 134.256 146.145 92.635  1.00 50.49  ? 143 THR B O   1 
ATOM 5595 C CB  . THR D 4 143 ? 135.107 146.246 89.863  1.00 50.49  ? 143 THR B CB  1 
ATOM 5596 O OG1 . THR D 4 143 ? 134.249 145.241 89.308  1.00 50.49  ? 143 THR B OG1 1 
ATOM 5597 C CG2 . THR D 4 143 ? 136.025 146.779 88.773  1.00 50.49  ? 143 THR B CG2 1 
ATOM 5598 N N   . GLY D 4 144 ? 135.033 144.029 92.625  1.00 49.46  ? 144 GLY B N   1 
ATOM 5599 C CA  . GLY D 4 144 ? 134.211 143.605 93.735  1.00 49.46  ? 144 GLY B CA  1 
ATOM 5600 C C   . GLY D 4 144 ? 135.013 142.767 94.715  1.00 49.46  ? 144 GLY B C   1 
ATOM 5601 O O   . GLY D 4 144 ? 136.147 142.365 94.442  1.00 49.46  ? 144 GLY B O   1 
ATOM 5602 N N   . TYR D 4 145 ? 134.399 142.516 95.869  1.00 48.57  ? 145 TYR B N   1 
ATOM 5603 C CA  . TYR D 4 145 ? 135.053 141.733 96.909  1.00 48.57  ? 145 TYR B CA  1 
ATOM 5604 C C   . TYR D 4 145 ? 135.306 140.309 96.430  1.00 48.57  ? 145 TYR B C   1 
ATOM 5605 O O   . TYR D 4 145 ? 134.457 139.692 95.782  1.00 48.57  ? 145 TYR B O   1 
ATOM 5606 C CB  . TYR D 4 145 ? 134.197 141.717 98.177  1.00 48.57  ? 145 TYR B CB  1 
ATOM 5607 C CG  . TYR D 4 145 ? 132.908 140.934 98.043  1.00 48.57  ? 145 TYR B CG  1 
ATOM 5608 C CD1 . TYR D 4 145 ? 131.793 141.493 97.433  1.00 48.57  ? 145 TYR B CD1 1 
ATOM 5609 C CD2 . TYR D 4 145 ? 132.808 139.635 98.526  1.00 48.57  ? 145 TYR B CD2 1 
ATOM 5610 C CE1 . TYR D 4 145 ? 130.616 140.781 97.307  1.00 48.57  ? 145 TYR B CE1 1 
ATOM 5611 C CE2 . TYR D 4 145 ? 131.635 138.916 98.404  1.00 48.57  ? 145 TYR B CE2 1 
ATOM 5612 C CZ  . TYR D 4 145 ? 130.542 139.494 97.794  1.00 48.57  ? 145 TYR B CZ  1 
ATOM 5613 O OH  . TYR D 4 145 ? 129.372 138.782 97.670  1.00 48.57  ? 145 TYR B OH  1 
ATOM 5614 N N   . LEU D 4 146 ? 136.488 139.789 96.749  1.00 42.37  ? 146 LEU B N   1 
ATOM 5615 C CA  . LEU D 4 146 ? 136.812 138.408 96.425  1.00 42.37  ? 146 LEU B CA  1 
ATOM 5616 C C   . LEU D 4 146 ? 136.159 137.467 97.427  1.00 42.37  ? 146 LEU B C   1 
ATOM 5617 O O   . LEU D 4 146 ? 136.163 137.719 98.635  1.00 42.37  ? 146 LEU B O   1 
ATOM 5618 C CB  . LEU D 4 146 ? 138.324 138.188 96.414  1.00 42.37  ? 146 LEU B CB  1 
ATOM 5619 C CG  . LEU D 4 146 ? 139.111 138.858 95.288  1.00 42.37  ? 146 LEU B CG  1 
ATOM 5620 C CD1 . LEU D 4 146 ? 139.630 140.208 95.737  1.00 42.37  ? 146 LEU B CD1 1 
ATOM 5621 C CD2 . LEU D 4 146 ? 140.250 137.969 94.823  1.00 42.37  ? 146 LEU B CD2 1 
ATOM 5622 N N   . SER D 4 147 ? 135.595 136.375 96.914  1.00 42.10  ? 147 SER B N   1 
ATOM 5623 C CA  . SER D 4 147 ? 134.925 135.391 97.748  1.00 42.10  ? 147 SER B CA  1 
ATOM 5624 C C   . SER D 4 147 ? 135.686 134.082 97.885  1.00 42.10  ? 147 SER B C   1 
ATOM 5625 O O   . SER D 4 147 ? 135.446 133.350 98.850  1.00 42.10  ? 147 SER B O   1 
ATOM 5626 C CB  . SER D 4 147 ? 133.521 135.095 97.200  1.00 42.10  ? 147 SER B CB  1 
ATOM 5627 O OG  . SER D 4 147 ? 133.582 134.646 95.857  1.00 42.10  ? 147 SER B OG  1 
ATOM 5628 N N   . CYS D 4 148 ? 136.592 133.771 96.960  1.00 39.72  ? 148 CYS B N   1 
ATOM 5629 C CA  . CYS D 4 148 ? 137.338 132.517 97.029  1.00 39.72  ? 148 CYS B CA  1 
ATOM 5630 C C   . CYS D 4 148 ? 138.589 132.630 96.173  1.00 39.72  ? 148 CYS B C   1 
ATOM 5631 O O   . CYS D 4 148 ? 138.490 132.779 94.951  1.00 39.72  ? 148 CYS B O   1 
ATOM 5632 C CB  . CYS D 4 148 ? 136.472 131.344 96.568  1.00 39.72  ? 148 CYS B CB  1 
ATOM 5633 S SG  . CYS D 4 148 ? 137.211 129.717 96.836  1.00 39.72  ? 148 CYS B SG  1 
ATOM 5634 N N   . CYS D 4 149 ? 139.755 132.559 96.809  1.00 38.28  ? 149 CYS B N   1 
ATOM 5635 C CA  . CYS D 4 149 ? 141.031 132.409 96.122  1.00 38.28  ? 149 CYS B CA  1 
ATOM 5636 C C   . CYS D 4 149 ? 141.467 130.955 96.254  1.00 38.28  ? 149 CYS B C   1 
ATOM 5637 O O   . CYS D 4 149 ? 141.520 130.422 97.367  1.00 38.28  ? 149 CYS B O   1 
ATOM 5638 C CB  . CYS D 4 149 ? 142.097 133.345 96.708  1.00 38.28  ? 149 CYS B CB  1 
ATOM 5639 S SG  . CYS D 4 149 ? 141.952 135.107 96.255  1.00 38.28  ? 149 CYS B SG  1 
ATOM 5640 N N   . ARG D 4 150 ? 141.756 130.311 95.125  1.00 34.31  ? 150 ARG B N   1 
ATOM 5641 C CA  . ARG D 4 150 ? 142.125 128.899 95.119  1.00 34.31  ? 150 ARG B CA  1 
ATOM 5642 C C   . ARG D 4 150 ? 143.357 128.689 94.253  1.00 34.31  ? 150 ARG B C   1 
ATOM 5643 O O   . ARG D 4 150 ? 143.430 129.209 93.137  1.00 34.31  ? 150 ARG B O   1 
ATOM 5644 C CB  . ARG D 4 150 ? 140.972 128.026 94.610  1.00 34.31  ? 150 ARG B CB  1 
ATOM 5645 C CG  . ARG D 4 150 ? 139.946 127.665 95.671  1.00 34.31  ? 150 ARG B CG  1 
ATOM 5646 C CD  . ARG D 4 150 ? 140.478 126.600 96.616  1.00 34.31  ? 150 ARG B CD  1 
ATOM 5647 N NE  . ARG D 4 150 ? 139.702 126.527 97.848  1.00 34.31  ? 150 ARG B NE  1 
ATOM 5648 C CZ  . ARG D 4 150 ? 139.892 127.310 98.901  1.00 34.31  ? 150 ARG B CZ  1 
ATOM 5649 N NH1 . ARG D 4 150 ? 140.830 128.242 98.909  1.00 34.31  ? 150 ARG B NH1 1 
ATOM 5650 N NH2 . ARG D 4 150 ? 139.121 127.153 99.973  1.00 34.31  ? 150 ARG B NH2 1 
ATOM 5651 N N   . PHE D 4 151 ? 144.308 127.910 94.762  1.00 35.45  ? 151 PHE B N   1 
ATOM 5652 C CA  . PHE D 4 151 ? 145.563 127.653 94.068  1.00 35.45  ? 151 PHE B CA  1 
ATOM 5653 C C   . PHE D 4 151 ? 145.434 126.434 93.164  1.00 35.45  ? 151 PHE B C   1 
ATOM 5654 O O   . PHE D 4 151 ? 144.984 125.371 93.603  1.00 35.45  ? 151 PHE B O   1 
ATOM 5655 C CB  . PHE D 4 151 ? 146.698 127.434 95.069  1.00 35.45  ? 151 PHE B CB  1 
ATOM 5656 C CG  . PHE D 4 151 ? 147.503 128.666 95.359  1.00 35.45  ? 151 PHE B CG  1 
ATOM 5657 C CD1 . PHE D 4 151 ? 148.441 129.125 94.450  1.00 35.45  ? 151 PHE B CD1 1 
ATOM 5658 C CD2 . PHE D 4 151 ? 147.332 129.359 96.545  1.00 35.45  ? 151 PHE B CD2 1 
ATOM 5659 C CE1 . PHE D 4 151 ? 149.187 130.256 94.715  1.00 35.45  ? 151 PHE B CE1 1 
ATOM 5660 C CE2 . PHE D 4 151 ? 148.076 130.489 96.815  1.00 35.45  ? 151 PHE B CE2 1 
ATOM 5661 C CZ  . PHE D 4 151 ? 149.004 130.939 95.899  1.00 35.45  ? 151 PHE B CZ  1 
ATOM 5662 N N   . LEU D 4 152 ? 145.832 126.593 91.902  1.00 38.94  ? 152 LEU B N   1 
ATOM 5663 C CA  . LEU D 4 152 ? 145.960 125.460 90.993  1.00 38.94  ? 152 LEU B CA  1 
ATOM 5664 C C   . LEU D 4 152 ? 147.354 124.850 91.050  1.00 38.94  ? 152 LEU B C   1 
ATOM 5665 O O   . LEU D 4 152 ? 147.494 123.624 91.108  1.00 38.94  ? 152 LEU B O   1 
ATOM 5666 C CB  . LEU D 4 152 ? 145.639 125.888 89.559  1.00 38.94  ? 152 LEU B CB  1 
ATOM 5667 C CG  . LEU D 4 152 ? 144.202 126.327 89.272  1.00 38.94  ? 152 LEU B CG  1 
ATOM 5668 C CD1 . LEU D 4 152 ? 144.104 127.842 89.240  1.00 38.94  ? 152 LEU B CD1 1 
ATOM 5669 C CD2 . LEU D 4 152 ? 143.709 125.727 87.965  1.00 38.94  ? 152 LEU B CD2 1 
ATOM 5670 N N   . ASP D 4 153 ? 148.385 125.688 91.036  1.00 43.01  ? 153 ASP B N   1 
ATOM 5671 C CA  . ASP D 4 153 ? 149.769 125.256 91.182  1.00 43.01  ? 153 ASP B CA  1 
ATOM 5672 C C   . ASP D 4 153 ? 150.576 126.450 91.680  1.00 43.01  ? 153 ASP B C   1 
ATOM 5673 O O   . ASP D 4 153 ? 150.015 127.457 92.125  1.00 43.01  ? 153 ASP B O   1 
ATOM 5674 C CB  . ASP D 4 153 ? 150.314 124.689 89.866  1.00 43.01  ? 153 ASP B CB  1 
ATOM 5675 C CG  . ASP D 4 153 ? 150.052 125.599 88.686  1.00 43.01  ? 153 ASP B CG  1 
ATOM 5676 O OD1 . ASP D 4 153 ? 149.421 126.657 88.882  1.00 43.01  ? 153 ASP B OD1 1 
ATOM 5677 O OD2 . ASP D 4 153 ? 150.475 125.257 87.562  1.00 43.01  ? 153 ASP B OD2 1 
ATOM 5678 N N   . ASP D 4 154 ? 151.903 126.340 91.605  1.00 46.57  ? 154 ASP B N   1 
ATOM 5679 C CA  . ASP D 4 154 ? 152.774 127.406 92.084  1.00 46.57  ? 154 ASP B CA  1 
ATOM 5680 C C   . ASP D 4 154 ? 152.764 128.637 91.187  1.00 46.57  ? 154 ASP B C   1 
ATOM 5681 O O   . ASP D 4 154 ? 153.303 129.674 91.590  1.00 46.57  ? 154 ASP B O   1 
ATOM 5682 C CB  . ASP D 4 154 ? 154.205 126.886 92.226  1.00 46.57  ? 154 ASP B CB  1 
ATOM 5683 N N   . ASN D 4 155 ? 152.173 128.558 89.992  1.00 49.40  ? 155 ASN B N   1 
ATOM 5684 C CA  . ASN D 4 155 ? 152.214 129.661 89.043  1.00 49.40  ? 155 ASN B CA  1 
ATOM 5685 C C   . ASN D 4 155 ? 150.848 130.143 88.576  1.00 49.40  ? 155 ASN B C   1 
ATOM 5686 O O   . ASN D 4 155 ? 150.776 131.203 87.943  1.00 49.40  ? 155 ASN B O   1 
ATOM 5687 C CB  . ASN D 4 155 ? 153.048 129.274 87.811  1.00 49.40  ? 155 ASN B CB  1 
ATOM 5688 C CG  . ASN D 4 155 ? 153.878 130.427 87.284  1.00 49.40  ? 155 ASN B CG  1 
ATOM 5689 O OD1 . ASN D 4 155 ? 153.695 131.575 87.690  1.00 49.40  ? 155 ASN B OD1 1 
ATOM 5690 N ND2 . ASN D 4 155 ? 154.797 130.128 86.374  1.00 49.40  ? 155 ASN B ND2 1 
ATOM 5691 N N   . GLN D 4 156 ? 149.770 129.413 88.858  1.00 46.83  ? 156 GLN B N   1 
ATOM 5692 C CA  . GLN D 4 156 ? 148.433 129.815 88.446  1.00 46.83  ? 156 GLN B CA  1 
ATOM 5693 C C   . GLN D 4 156 ? 147.495 129.801 89.644  1.00 46.83  ? 156 GLN B C   1 
ATOM 5694 O O   . GLN D 4 156 ? 147.558 128.900 90.484  1.00 46.83  ? 156 GLN B O   1 
ATOM 5695 C CB  . GLN D 4 156 ? 147.882 128.898 87.345  1.00 46.83  ? 156 GLN B CB  1 
ATOM 5696 C CG  . GLN D 4 156 ? 148.788 128.761 86.134  1.00 46.83  ? 156 GLN B CG  1 
ATOM 5697 C CD  . GLN D 4 156 ? 148.012 128.634 84.838  1.00 46.83  ? 156 GLN B CD  1 
ATOM 5698 O OE1 . GLN D 4 156 ? 147.675 127.531 84.409  1.00 46.83  ? 156 GLN B OE1 1 
ATOM 5699 N NE2 . GLN D 4 156 ? 147.726 129.766 84.207  1.00 46.83  ? 156 GLN B NE2 1 
ATOM 5700 N N   . ILE D 4 157 ? 146.628 130.810 89.715  1.00 41.33  ? 157 ILE B N   1 
ATOM 5701 C CA  . ILE D 4 157 ? 145.623 130.918 90.764  1.00 41.33  ? 157 ILE B CA  1 
ATOM 5702 C C   . ILE D 4 157 ? 144.296 131.289 90.115  1.00 41.33  ? 157 ILE B C   1 
ATOM 5703 O O   . ILE D 4 157 ? 144.257 131.862 89.021  1.00 41.33  ? 157 ILE B O   1 
ATOM 5704 C CB  . ILE D 4 157 ? 146.029 131.952 91.841  1.00 41.33  ? 157 ILE B CB  1 
ATOM 5705 C CG1 . ILE D 4 157 ? 145.229 131.744 93.129  1.00 41.33  ? 157 ILE B CG1 1 
ATOM 5706 C CG2 . ILE D 4 157 ? 145.836 133.364 91.325  1.00 41.33  ? 157 ILE B CG2 1 
ATOM 5707 C CD1 . ILE D 4 157 ? 145.776 132.495 94.319  1.00 41.33  ? 157 ILE B CD1 1 
ATOM 5708 N N   . VAL D 4 158 ? 143.201 130.942 90.787  1.00 40.31  ? 158 VAL B N   1 
ATOM 5709 C CA  . VAL D 4 158 ? 141.856 131.247 90.319  1.00 40.31  ? 158 VAL B CA  1 
ATOM 5710 C C   . VAL D 4 158 ? 141.110 131.978 91.427  1.00 40.31  ? 158 VAL B C   1 
ATOM 5711 O O   . VAL D 4 158 ? 141.185 131.596 92.600  1.00 40.31  ? 158 VAL B O   1 
ATOM 5712 C CB  . VAL D 4 158 ? 141.097 129.976 89.875  1.00 40.31  ? 158 VAL B CB  1 
ATOM 5713 C CG1 . VAL D 4 158 ? 141.025 128.958 91.004  1.00 40.31  ? 158 VAL B CG1 1 
ATOM 5714 C CG2 . VAL D 4 158 ? 139.704 130.329 89.374  1.00 40.31  ? 158 VAL B CG2 1 
ATOM 5715 N N   . THR D 4 159 ? 140.411 133.048 91.054  1.00 42.52  ? 159 THR B N   1 
ATOM 5716 C CA  . THR D 4 159 ? 139.695 133.890 91.999  1.00 42.52  ? 159 THR B CA  1 
ATOM 5717 C C   . THR D 4 159 ? 138.287 134.148 91.484  1.00 42.52  ? 159 THR B C   1 
ATOM 5718 O O   . THR D 4 159 ? 138.029 134.085 90.281  1.00 42.52  ? 159 THR B O   1 
ATOM 5719 C CB  . THR D 4 159 ? 140.407 135.235 92.215  1.00 42.52  ? 159 THR B CB  1 
ATOM 5720 O OG1 . THR D 4 159 ? 140.496 135.934 90.968  1.00 42.52  ? 159 THR B OG1 1 
ATOM 5721 C CG2 . THR D 4 159 ? 141.809 135.018 92.757  1.00 42.52  ? 159 THR B CG2 1 
ATOM 5722 N N   . SER D 4 160 ? 137.377 134.436 92.410  1.00 41.88  ? 160 SER B N   1 
ATOM 5723 C CA  . SER D 4 160 ? 136.016 134.835 92.083  1.00 41.88  ? 160 SER B CA  1 
ATOM 5724 C C   . SER D 4 160 ? 135.676 136.090 92.870  1.00 41.88  ? 160 SER B C   1 
ATOM 5725 O O   . SER D 4 160 ? 136.017 136.197 94.051  1.00 41.88  ? 160 SER B O   1 
ATOM 5726 C CB  . SER D 4 160 ? 135.012 133.724 92.404  1.00 41.88  ? 160 SER B CB  1 
ATOM 5727 O OG  . SER D 4 160 ? 134.555 133.821 93.741  1.00 41.88  ? 160 SER B OG  1 
ATOM 5728 N N   . SER D 4 161 ? 135.002 137.037 92.223  1.00 47.12  ? 161 SER B N   1 
ATOM 5729 C CA  . SER D 4 161 ? 134.722 138.321 92.844  1.00 47.12  ? 161 SER B CA  1 
ATOM 5730 C C   . SER D 4 161 ? 133.221 138.564 92.918  1.00 47.12  ? 161 SER B C   1 
ATOM 5731 O O   . SER D 4 161 ? 132.412 137.816 92.362  1.00 47.12  ? 161 SER B O   1 
ATOM 5732 C CB  . SER D 4 161 ? 135.406 139.460 92.078  1.00 47.12  ? 161 SER B CB  1 
ATOM 5733 O OG  . SER D 4 161 ? 134.825 140.711 92.401  1.00 47.12  ? 161 SER B OG  1 
ATOM 5734 N N   . GLY D 4 162 ? 132.857 139.633 93.624  1.00 48.19  ? 162 GLY B N   1 
ATOM 5735 C CA  . GLY D 4 162 ? 131.477 140.045 93.760  1.00 48.19  ? 162 GLY B CA  1 
ATOM 5736 C C   . GLY D 4 162 ? 130.909 140.792 92.579  1.00 48.19  ? 162 GLY B C   1 
ATOM 5737 O O   . GLY D 4 162 ? 129.721 141.126 92.582  1.00 48.19  ? 162 GLY B O   1 
ATOM 5738 N N   . ASP D 4 163 ? 131.727 141.072 91.562  1.00 49.57  ? 163 ASP B N   1 
ATOM 5739 C CA  . ASP D 4 163 ? 131.266 141.703 90.332  1.00 49.57  ? 163 ASP B CA  1 
ATOM 5740 C C   . ASP D 4 163 ? 130.878 140.685 89.266  1.00 49.57  ? 163 ASP B C   1 
ATOM 5741 O O   . ASP D 4 163 ? 130.959 140.986 88.067  1.00 49.57  ? 163 ASP B O   1 
ATOM 5742 C CB  . ASP D 4 163 ? 132.334 142.658 89.797  1.00 49.57  ? 163 ASP B CB  1 
ATOM 5743 C CG  . ASP D 4 163 ? 133.722 142.050 89.810  1.00 49.57  ? 163 ASP B CG  1 
ATOM 5744 O OD1 . ASP D 4 163 ? 133.834 140.816 89.672  1.00 49.57  ? 163 ASP B OD1 1 
ATOM 5745 O OD2 . ASP D 4 163 ? 134.703 142.809 89.958  1.00 49.57  ? 163 ASP B OD2 1 
ATOM 5746 N N   . THR D 4 164 ? 130.462 139.485 89.681  1.00 50.48  ? 164 THR B N   1 
ATOM 5747 C CA  . THR D 4 164 ? 130.023 138.422 88.773  1.00 50.48  ? 164 THR B CA  1 
ATOM 5748 C C   . THR D 4 164 ? 131.118 138.038 87.779  1.00 50.48  ? 164 THR B C   1 
ATOM 5749 O O   . THR D 4 164 ? 130.846 137.743 86.614  1.00 50.48  ? 164 THR B O   1 
ATOM 5750 C CB  . THR D 4 164 ? 128.739 138.812 88.034  1.00 50.48  ? 164 THR B CB  1 
ATOM 5751 O OG1 . THR D 4 164 ? 129.055 139.712 86.964  1.00 50.48  ? 164 THR B OG1 1 
ATOM 5752 C CG2 . THR D 4 164 ? 127.750 139.484 88.979  1.00 50.48  ? 164 THR B CG2 1 
ATOM 5753 N N   . THR D 4 165 ? 132.370 138.040 88.239  1.00 49.60  ? 165 THR B N   1 
ATOM 5754 C CA  . THR D 4 165 ? 133.498 137.700 87.382  1.00 49.60  ? 165 THR B CA  1 
ATOM 5755 C C   . THR D 4 165 ? 134.455 136.762 88.103  1.00 49.60  ? 165 THR B C   1 
ATOM 5756 O O   . THR D 4 165 ? 134.752 136.946 89.289  1.00 49.60  ? 165 THR B O   1 
ATOM 5757 C CB  . THR D 4 165 ? 134.272 138.949 86.927  1.00 49.60  ? 165 THR B CB  1 
ATOM 5758 O OG1 . THR D 4 165 ? 134.779 139.646 88.072  1.00 49.60  ? 165 THR B OG1 1 
ATOM 5759 C CG2 . THR D 4 165 ? 133.381 139.882 86.117  1.00 49.60  ? 165 THR B CG2 1 
ATOM 5760 N N   . CYS D 4 166 ? 134.951 135.770 87.368  1.00 48.63  ? 166 CYS B N   1 
ATOM 5761 C CA  . CYS D 4 166 ? 136.039 134.919 87.820  1.00 48.63  ? 166 CYS B CA  1 
ATOM 5762 C C   . CYS D 4 166 ? 137.282 135.221 86.993  1.00 48.63  ? 166 CYS B C   1 
ATOM 5763 O O   . CYS D 4 166 ? 137.190 135.662 85.845  1.00 48.63  ? 166 CYS B O   1 
ATOM 5764 C CB  . CYS D 4 166 ? 135.674 133.436 87.703  1.00 48.63  ? 166 CYS B CB  1 
ATOM 5765 S SG  . CYS D 4 166 ? 134.141 132.975 88.544  1.00 48.63  ? 166 CYS B SG  1 
ATOM 5766 N N   . ALA D 4 167 ? 138.450 134.987 87.583  1.00 44.14  ? 167 ALA B N   1 
ATOM 5767 C CA  . ALA D 4 167 ? 139.703 135.334 86.929  1.00 44.14  ? 167 ALA B CA  1 
ATOM 5768 C C   . ALA D 4 167 ? 140.766 134.290 87.228  1.00 44.14  ? 167 ALA B C   1 
ATOM 5769 O O   . ALA D 4 167 ? 141.041 133.991 88.394  1.00 44.14  ? 167 ALA B O   1 
ATOM 5770 C CB  . ALA D 4 167 ? 140.189 136.719 87.371  1.00 44.14  ? 167 ALA B CB  1 
ATOM 5771 N N   . LEU D 4 168 ? 141.352 133.737 86.171  1.00 43.64  ? 168 LEU B N   1 
ATOM 5772 C CA  . LEU D 4 168 ? 142.561 132.933 86.263  1.00 43.64  ? 168 LEU B CA  1 
ATOM 5773 C C   . LEU D 4 168 ? 143.750 133.861 86.055  1.00 43.64  ? 168 LEU B C   1 
ATOM 5774 O O   . LEU D 4 168 ? 143.904 134.440 84.973  1.00 43.64  ? 168 LEU B O   1 
ATOM 5775 C CB  . LEU D 4 168 ? 142.559 131.814 85.222  1.00 43.64  ? 168 LEU B CB  1 
ATOM 5776 C CG  . LEU D 4 168 ? 143.862 131.029 85.064  1.00 43.64  ? 168 LEU B CG  1 
ATOM 5777 C CD1 . LEU D 4 168 ? 144.077 130.091 86.241  1.00 43.64  ? 168 LEU B CD1 1 
ATOM 5778 C CD2 . LEU D 4 168 ? 143.876 130.267 83.749  1.00 43.64  ? 168 LEU B CD2 1 
ATOM 5779 N N   . TRP D 4 169 ? 144.578 134.001 87.088  1.00 44.44  ? 169 TRP B N   1 
ATOM 5780 C CA  . TRP D 4 169 ? 145.669 134.960 87.106  1.00 44.44  ? 169 TRP B CA  1 
ATOM 5781 C C   . TRP D 4 169 ? 146.990 134.282 86.750  1.00 44.44  ? 169 TRP B C   1 
ATOM 5782 O O   . TRP D 4 169 ? 147.053 133.091 86.439  1.00 44.44  ? 169 TRP B O   1 
ATOM 5783 C CB  . TRP D 4 169 ? 145.778 135.631 88.478  1.00 44.44  ? 169 TRP B CB  1 
ATOM 5784 C CG  . TRP D 4 169 ? 144.527 136.292 88.960  1.00 44.44  ? 169 TRP B CG  1 
ATOM 5785 C CD1 . TRP D 4 169 ? 143.393 135.679 89.406  1.00 44.44  ? 169 TRP B CD1 1 
ATOM 5786 C CD2 . TRP D 4 169 ? 144.289 137.700 89.069  1.00 44.44  ? 169 TRP B CD2 1 
ATOM 5787 N NE1 . TRP D 4 169 ? 142.461 136.617 89.776  1.00 44.44  ? 169 TRP B NE1 1 
ATOM 5788 C CE2 . TRP D 4 169 ? 142.987 137.866 89.578  1.00 44.44  ? 169 TRP B CE2 1 
ATOM 5789 C CE3 . TRP D 4 169 ? 145.050 138.837 88.779  1.00 44.44  ? 169 TRP B CE3 1 
ATOM 5790 C CZ2 . TRP D 4 169 ? 142.428 139.122 89.804  1.00 44.44  ? 169 TRP B CZ2 1 
ATOM 5791 C CZ3 . TRP D 4 169 ? 144.495 140.081 89.006  1.00 44.44  ? 169 TRP B CZ3 1 
ATOM 5792 C CH2 . TRP D 4 169 ? 143.197 140.214 89.512  1.00 44.44  ? 169 TRP B CH2 1 
ATOM 5793 N N   . ASP D 4 170 ? 148.062 135.070 86.802  1.00 52.45  ? 170 ASP B N   1 
ATOM 5794 C CA  . ASP D 4 170 ? 149.425 134.574 86.629  1.00 52.45  ? 170 ASP B CA  1 
ATOM 5795 C C   . ASP D 4 170 ? 150.294 135.265 87.670  1.00 52.45  ? 170 ASP B C   1 
ATOM 5796 O O   . ASP D 4 170 ? 150.530 136.474 87.578  1.00 52.45  ? 170 ASP B O   1 
ATOM 5797 C CB  . ASP D 4 170 ? 149.940 134.837 85.215  1.00 52.45  ? 170 ASP B CB  1 
ATOM 5798 C CG  . ASP D 4 170 ? 151.107 133.943 84.844  1.00 52.45  ? 170 ASP B CG  1 
ATOM 5799 O OD1 . ASP D 4 170 ? 152.169 134.046 85.493  1.00 52.45  ? 170 ASP B OD1 1 
ATOM 5800 O OD2 . ASP D 4 170 ? 150.962 133.135 83.902  1.00 52.45  ? 170 ASP B OD2 1 
ATOM 5801 N N   . ILE D 4 171 ? 150.764 134.502 88.658  1.00 49.84  ? 171 ILE B N   1 
ATOM 5802 C CA  . ILE D 4 171 ? 151.535 135.085 89.753  1.00 49.84  ? 171 ILE B CA  1 
ATOM 5803 C C   . ILE D 4 171 ? 152.861 135.640 89.244  1.00 49.84  ? 171 ILE B C   1 
ATOM 5804 O O   . ILE D 4 171 ? 153.333 136.682 89.714  1.00 49.84  ? 171 ILE B O   1 
ATOM 5805 C CB  . ILE D 4 171 ? 151.742 134.052 90.878  1.00 49.84  ? 171 ILE B CB  1 
ATOM 5806 C CG1 . ILE D 4 171 ? 150.403 133.641 91.500  1.00 49.84  ? 171 ILE B CG1 1 
ATOM 5807 C CG2 . ILE D 4 171 ? 152.670 134.599 91.953  1.00 49.84  ? 171 ILE B CG2 1 
ATOM 5808 C CD1 . ILE D 4 171 ? 149.726 132.460 90.840  1.00 49.84  ? 171 ILE B CD1 1 
ATOM 5809 N N   . GLU D 4 172 ? 153.478 134.961 88.274  1.00 52.76  ? 172 GLU B N   1 
ATOM 5810 C CA  . GLU D 4 172 ? 154.776 135.400 87.772  1.00 52.76  ? 172 GLU B CA  1 
ATOM 5811 C C   . GLU D 4 172 ? 154.690 136.782 87.133  1.00 52.76  ? 172 GLU B C   1 
ATOM 5812 O O   . GLU D 4 172 ? 155.574 137.623 87.335  1.00 52.76  ? 172 GLU B O   1 
ATOM 5813 C CB  . GLU D 4 172 ? 155.324 134.381 86.773  1.00 52.76  ? 172 GLU B CB  1 
ATOM 5814 N N   . THR D 4 173 ? 153.634 137.036 86.360  1.00 54.11  ? 173 THR B N   1 
ATOM 5815 C CA  . THR D 4 173 ? 153.466 138.322 85.695  1.00 54.11  ? 173 THR B CA  1 
ATOM 5816 C C   . THR D 4 173 ? 152.561 139.283 86.453  1.00 54.11  ? 173 THR B C   1 
ATOM 5817 O O   . THR D 4 173 ? 152.601 140.488 86.181  1.00 54.11  ? 173 THR B O   1 
ATOM 5818 C CB  . THR D 4 173 ? 152.905 138.124 84.281  1.00 54.11  ? 173 THR B CB  1 
ATOM 5819 O OG1 . THR D 4 173 ? 151.615 137.504 84.359  1.00 54.11  ? 173 THR B OG1 1 
ATOM 5820 C CG2 . THR D 4 173 ? 153.835 137.245 83.458  1.00 54.11  ? 173 THR B CG2 1 
ATOM 5821 N N   . GLY D 4 174 ? 151.753 138.789 87.388  1.00 54.15  ? 174 GLY B N   1 
ATOM 5822 C CA  . GLY D 4 174 ? 150.871 139.658 88.141  1.00 54.15  ? 174 GLY B CA  1 
ATOM 5823 C C   . GLY D 4 174 ? 149.708 140.218 87.357  1.00 54.15  ? 174 GLY B C   1 
ATOM 5824 O O   . GLY D 4 174 ? 149.155 141.251 87.742  1.00 54.15  ? 174 GLY B O   1 
ATOM 5825 N N   . GLN D 4 175 ? 149.317 139.564 86.266  1.00 51.91  ? 175 GLN B N   1 
ATOM 5826 C CA  . GLN D 4 175 ? 148.218 140.020 85.428  1.00 51.91  ? 175 GLN B CA  1 
ATOM 5827 C C   . GLN D 4 175 ? 147.249 138.873 85.188  1.00 51.91  ? 175 GLN B C   1 
ATOM 5828 O O   . GLN D 4 175 ? 147.626 137.699 85.239  1.00 51.91  ? 175 GLN B O   1 
ATOM 5829 C CB  . GLN D 4 175 ? 148.722 140.567 84.084  1.00 51.91  ? 175 GLN B CB  1 
ATOM 5830 C CG  . GLN D 4 175 ? 149.597 141.803 84.204  1.00 51.91  ? 175 GLN B CG  1 
ATOM 5831 C CD  . GLN D 4 175 ? 148.837 143.005 84.730  1.00 51.91  ? 175 GLN B CD  1 
ATOM 5832 O OE1 . GLN D 4 175 ? 147.677 143.223 84.379  1.00 51.91  ? 175 GLN B OE1 1 
ATOM 5833 N NE2 . GLN D 4 175 ? 149.489 143.793 85.576  1.00 51.91  ? 175 GLN B NE2 1 
ATOM 5834 N N   . GLN D 4 176 ? 145.991 139.225 84.933  1.00 49.03  ? 176 GLN B N   1 
ATOM 5835 C CA  . GLN D 4 176 ? 144.972 138.219 84.664  1.00 49.03  ? 176 GLN B CA  1 
ATOM 5836 C C   . GLN D 4 176 ? 145.269 137.505 83.352  1.00 49.03  ? 176 GLN B C   1 
ATOM 5837 O O   . GLN D 4 176 ? 145.599 138.140 82.346  1.00 49.03  ? 176 GLN B O   1 
ATOM 5838 C CB  . GLN D 4 176 ? 143.587 138.861 84.608  1.00 49.03  ? 176 GLN B CB  1 
ATOM 5839 C CG  . GLN D 4 176 ? 143.299 139.836 85.734  1.00 49.03  ? 176 GLN B CG  1 
ATOM 5840 C CD  . GLN D 4 176 ? 141.872 140.350 85.706  1.00 49.03  ? 176 GLN B CD  1 
ATOM 5841 O OE1 . GLN D 4 176 ? 141.377 140.783 84.666  1.00 49.03  ? 176 GLN B OE1 1 
ATOM 5842 N NE2 . GLN D 4 176 ? 141.203 140.301 86.852  1.00 49.03  ? 176 GLN B NE2 1 
ATOM 5843 N N   . THR D 4 177 ? 145.152 136.179 83.367  1.00 50.89  ? 177 THR B N   1 
ATOM 5844 C CA  . THR D 4 177 ? 145.336 135.384 82.160  1.00 50.89  ? 177 THR B CA  1 
ATOM 5845 C C   . THR D 4 177 ? 144.015 135.111 81.452  1.00 50.89  ? 177 THR B C   1 
ATOM 5846 O O   . THR D 4 177 ? 143.935 135.220 80.224  1.00 50.89  ? 177 THR B O   1 
ATOM 5847 C CB  . THR D 4 177 ? 146.033 134.062 82.500  1.00 50.89  ? 177 THR B CB  1 
ATOM 5848 O OG1 . THR D 4 177 ? 147.370 134.326 82.943  1.00 50.89  ? 177 THR B OG1 1 
ATOM 5849 C CG2 . THR D 4 177 ? 146.082 133.149 81.283  1.00 50.89  ? 177 THR B CG2 1 
ATOM 5850 N N   . THR D 4 178 ? 142.971 134.773 82.206  1.00 49.35  ? 178 THR B N   1 
ATOM 5851 C CA  . THR D 4 178 ? 141.677 134.459 81.616  1.00 49.35  ? 178 THR B CA  1 
ATOM 5852 C C   . THR D 4 178 ? 140.573 135.059 82.475  1.00 49.35  ? 178 THR B C   1 
ATOM 5853 O O   . THR D 4 178 ? 140.653 135.030 83.705  1.00 49.35  ? 178 THR B O   1 
ATOM 5854 C CB  . THR D 4 178 ? 141.483 132.943 81.477  1.00 49.35  ? 178 THR B CB  1 
ATOM 5855 O OG1 . THR D 4 178 ? 142.527 132.401 80.658  1.00 49.35  ? 178 THR B OG1 1 
ATOM 5856 C CG2 . THR D 4 178 ? 140.142 132.627 80.833  1.00 49.35  ? 178 THR B CG2 1 
ATOM 5857 N N   . THR D 4 179 ? 139.551 135.609 81.824  1.00 51.37  ? 179 THR B N   1 
ATOM 5858 C CA  . THR D 4 179 ? 138.405 136.201 82.504  1.00 51.37  ? 179 THR B CA  1 
ATOM 5859 C C   . THR D 4 179 ? 137.150 135.411 82.152  1.00 51.37  ? 179 THR B C   1 
ATOM 5860 O O   . THR D 4 179 ? 136.848 135.216 80.970  1.00 51.37  ? 179 THR B O   1 
ATOM 5861 C CB  . THR D 4 179 ? 138.238 137.672 82.119  1.00 51.37  ? 179 THR B CB  1 
ATOM 5862 O OG1 . THR D 4 179 ? 139.412 138.402 82.494  1.00 51.37  ? 179 THR B OG1 1 
ATOM 5863 C CG2 . THR D 4 179 ? 137.029 138.272 82.821  1.00 51.37  ? 179 THR B CG2 1 
ATOM 5864 N N   . PHE D 4 180 ? 136.426 134.962 83.175  1.00 51.64  ? 180 PHE B N   1 
ATOM 5865 C CA  . PHE D 4 180 ? 135.174 134.237 83.008  1.00 51.64  ? 180 PHE B CA  1 
ATOM 5866 C C   . PHE D 4 180 ? 134.024 135.133 83.450  1.00 51.64  ? 180 PHE B C   1 
ATOM 5867 O O   . PHE D 4 180 ? 134.001 135.604 84.595  1.00 51.64  ? 180 PHE B O   1 
ATOM 5868 C CB  . PHE D 4 180 ? 135.175 132.937 83.814  1.00 51.64  ? 180 PHE B CB  1 
ATOM 5869 C CG  . PHE D 4 180 ? 136.464 132.169 83.734  1.00 51.64  ? 180 PHE B CG  1 
ATOM 5870 C CD1 . PHE D 4 180 ? 136.678 131.254 82.717  1.00 51.64  ? 180 PHE B CD1 1 
ATOM 5871 C CD2 . PHE D 4 180 ? 137.456 132.352 84.683  1.00 51.64  ? 180 PHE B CD2 1 
ATOM 5872 C CE1 . PHE D 4 180 ? 137.859 130.542 82.644  1.00 51.64  ? 180 PHE B CE1 1 
ATOM 5873 C CE2 . PHE D 4 180 ? 138.640 131.644 84.614  1.00 51.64  ? 180 PHE B CE2 1 
ATOM 5874 C CZ  . PHE D 4 180 ? 138.841 130.737 83.593  1.00 51.64  ? 180 PHE B CZ  1 
ATOM 5875 N N   . THR D 4 181 ? 133.075 135.362 82.545  1.00 53.68  ? 181 THR B N   1 
ATOM 5876 C CA  . THR D 4 181 ? 131.919 136.207 82.798  1.00 53.68  ? 181 THR B CA  1 
ATOM 5877 C C   . THR D 4 181 ? 130.658 135.494 82.330  1.00 53.68  ? 181 THR B C   1 
ATOM 5878 O O   . THR D 4 181 ? 130.702 134.597 81.485  1.00 53.68  ? 181 THR B O   1 
ATOM 5879 C CB  . THR D 4 181 ? 132.040 137.566 82.091  1.00 53.68  ? 181 THR B CB  1 
ATOM 5880 O OG1 . THR D 4 181 ? 132.278 137.361 80.693  1.00 53.68  ? 181 THR B OG1 1 
ATOM 5881 C CG2 . THR D 4 181 ? 133.181 138.381 82.682  1.00 53.68  ? 181 THR B CG2 1 
ATOM 5882 N N   . GLY D 4 182 ? 129.525 135.907 82.894  1.00 54.22  ? 182 GLY B N   1 
ATOM 5883 C CA  . GLY D 4 182 ? 128.249 135.314 82.546  1.00 54.22  ? 182 GLY B CA  1 
ATOM 5884 C C   . GLY D 4 182 ? 127.307 135.190 83.724  1.00 54.22  ? 182 GLY B C   1 
ATOM 5885 O O   . GLY D 4 182 ? 126.095 135.036 83.546  1.00 54.22  ? 182 GLY B O   1 
ATOM 5886 N N   . HIS D 4 183 ? 127.854 135.250 84.935  1.00 52.74  ? 183 HIS B N   1 
ATOM 5887 C CA  . HIS D 4 183 ? 127.029 135.210 86.133  1.00 52.74  ? 183 HIS B CA  1 
ATOM 5888 C C   . HIS D 4 183 ? 126.194 136.479 86.252  1.00 52.74  ? 183 HIS B C   1 
ATOM 5889 O O   . HIS D 4 183 ? 126.630 137.569 85.870  1.00 52.74  ? 183 HIS B O   1 
ATOM 5890 C CB  . HIS D 4 183 ? 127.904 135.040 87.375  1.00 52.74  ? 183 HIS B CB  1 
ATOM 5891 C CG  . HIS D 4 183 ? 128.213 133.613 87.705  1.00 52.74  ? 183 HIS B CG  1 
ATOM 5892 N ND1 . HIS D 4 183 ? 129.254 133.249 88.531  1.00 52.74  ? 183 HIS B ND1 1 
ATOM 5893 C CD2 . HIS D 4 183 ? 127.607 132.461 87.334  1.00 52.74  ? 183 HIS B CD2 1 
ATOM 5894 C CE1 . HIS D 4 183 ? 129.283 131.933 88.646  1.00 52.74  ? 183 HIS B CE1 1 
ATOM 5895 N NE2 . HIS D 4 183 ? 128.294 131.431 87.930  1.00 52.74  ? 183 HIS B NE2 1 
ATOM 5896 N N   . THR D 4 184 ? 124.980 136.330 86.780  1.00 56.10  ? 184 THR B N   1 
ATOM 5897 C CA  . THR D 4 184 ? 124.108 137.474 87.017  1.00 56.10  ? 184 THR B CA  1 
ATOM 5898 C C   . THR D 4 184 ? 124.238 138.005 88.440  1.00 56.10  ? 184 THR B C   1 
ATOM 5899 O O   . THR D 4 184 ? 124.307 139.222 88.643  1.00 56.10  ? 184 THR B O   1 
ATOM 5900 C CB  . THR D 4 184 ? 122.651 137.097 86.733  1.00 56.10  ? 184 THR B CB  1 
ATOM 5901 O OG1 . THR D 4 184 ? 122.545 136.557 85.410  1.00 56.10  ? 184 THR B OG1 1 
ATOM 5902 C CG2 . THR D 4 184 ? 121.751 138.319 86.847  1.00 56.10  ? 184 THR B CG2 1 
ATOM 5903 N N   . GLY D 4 185 ? 124.277 137.112 89.430  1.00 52.25  ? 185 GLY B N   1 
ATOM 5904 C CA  . GLY D 4 185 ? 124.470 137.500 90.808  1.00 52.25  ? 185 GLY B CA  1 
ATOM 5905 C C   . GLY D 4 185 ? 125.927 137.389 91.235  1.00 52.25  ? 185 GLY B C   1 
ATOM 5906 O O   . GLY D 4 185 ? 126.780 136.877 90.517  1.00 52.25  ? 185 GLY B O   1 
ATOM 5907 N N   . ASP D 4 186 ? 126.194 137.887 92.441  1.00 54.66  ? 186 ASP B N   1 
ATOM 5908 C CA  . ASP D 4 186 ? 127.551 137.883 92.970  1.00 54.66  ? 186 ASP B CA  1 
ATOM 5909 C C   . ASP D 4 186 ? 128.049 136.457 93.164  1.00 54.66  ? 186 ASP B C   1 
ATOM 5910 O O   . ASP D 4 186 ? 127.345 135.609 93.719  1.00 54.66  ? 186 ASP B O   1 
ATOM 5911 C CB  . ASP D 4 186 ? 127.599 138.643 94.294  1.00 54.66  ? 186 ASP B CB  1 
ATOM 5912 C CG  . ASP D 4 186 ? 126.977 140.019 94.197  1.00 54.66  ? 186 ASP B CG  1 
ATOM 5913 O OD1 . ASP D 4 186 ? 126.987 140.603 93.093  1.00 54.66  ? 186 ASP B OD1 1 
ATOM 5914 O OD2 . ASP D 4 186 ? 126.476 140.517 95.225  1.00 54.66  ? 186 ASP B OD2 1 
ATOM 5915 N N   . VAL D 4 187 ? 129.271 136.199 92.710  1.00 47.60  ? 187 VAL B N   1 
ATOM 5916 C CA  . VAL D 4 187 ? 129.878 134.880 92.843  1.00 47.60  ? 187 VAL B CA  1 
ATOM 5917 C C   . VAL D 4 187 ? 130.263 134.659 94.298  1.00 47.60  ? 187 VAL B C   1 
ATOM 5918 O O   . VAL D 4 187 ? 130.872 135.531 94.930  1.00 47.60  ? 187 VAL B O   1 
ATOM 5919 C CB  . VAL D 4 187 ? 131.098 134.749 91.920  1.00 47.60  ? 187 VAL B CB  1 
ATOM 5920 C CG1 . VAL D 4 187 ? 131.505 133.301 91.799  1.00 47.60  ? 187 VAL B CG1 1 
ATOM 5921 C CG2 . VAL D 4 187 ? 130.795 135.339 90.555  1.00 47.60  ? 187 VAL B CG2 1 
ATOM 5922 N N   . MET D 4 188 ? 129.912 133.492 94.839  1.00 47.46  ? 188 MET B N   1 
ATOM 5923 C CA  . MET D 4 188 ? 130.112 133.227 96.258  1.00 47.46  ? 188 MET B CA  1 
ATOM 5924 C C   . MET D 4 188 ? 131.204 132.214 96.559  1.00 47.46  ? 188 MET B C   1 
ATOM 5925 O O   . MET D 4 188 ? 131.890 132.357 97.573  1.00 47.46  ? 188 MET B O   1 
ATOM 5926 C CB  . MET D 4 188 ? 128.803 132.746 96.899  1.00 47.46  ? 188 MET B CB  1 
ATOM 5927 C CG  . MET D 4 188 ? 127.792 133.850 97.217  1.00 47.46  ? 188 MET B CG  1 
ATOM 5928 S SD  . MET D 4 188 ? 128.450 135.515 97.475  1.00 47.46  ? 188 MET B SD  1 
ATOM 5929 C CE  . MET D 4 188 ? 129.489 135.300 98.924  1.00 47.46  ? 188 MET B CE  1 
ATOM 5930 N N   . SER D 4 189 ? 131.384 131.196 95.722  1.00 43.64  ? 189 SER B N   1 
ATOM 5931 C CA  . SER D 4 189 ? 132.388 130.179 95.999  1.00 43.64  ? 189 SER B CA  1 
ATOM 5932 C C   . SER D 4 189 ? 132.792 129.501 94.700  1.00 43.64  ? 189 SER B C   1 
ATOM 5933 O O   . SER D 4 189 ? 132.094 129.588 93.686  1.00 43.64  ? 189 SER B O   1 
ATOM 5934 C CB  . SER D 4 189 ? 131.875 129.145 97.007  1.00 43.64  ? 189 SER B CB  1 
ATOM 5935 O OG  . SER D 4 189 ? 130.726 128.479 96.514  1.00 43.64  ? 189 SER B OG  1 
ATOM 5936 N N   . LEU D 4 190 ? 133.937 128.824 94.749  1.00 38.73  ? 190 LEU B N   1 
ATOM 5937 C CA  . LEU D 4 190 ? 134.424 128.044 93.622  1.00 38.73  ? 190 LEU B CA  1 
ATOM 5938 C C   . LEU D 4 190 ? 135.180 126.838 94.159  1.00 38.73  ? 190 LEU B C   1 
ATOM 5939 O O   . LEU D 4 190 ? 135.640 126.827 95.303  1.00 38.73  ? 190 LEU B O   1 
ATOM 5940 C CB  . LEU D 4 190 ? 135.315 128.880 92.691  1.00 38.73  ? 190 LEU B CB  1 
ATOM 5941 C CG  . LEU D 4 190 ? 136.687 129.342 93.194  1.00 38.73  ? 190 LEU B CG  1 
ATOM 5942 C CD1 . LEU D 4 190 ? 137.785 128.373 92.777  1.00 38.73  ? 190 LEU B CD1 1 
ATOM 5943 C CD2 . LEU D 4 190 ? 136.998 130.742 92.698  1.00 38.73  ? 190 LEU B CD2 1 
ATOM 5944 N N   . SER D 4 191 ? 135.303 125.818 93.314  1.00 38.10  ? 191 SER B N   1 
ATOM 5945 C CA  . SER D 4 191 ? 136.033 124.609 93.670  1.00 38.10  ? 191 SER B CA  1 
ATOM 5946 C C   . SER D 4 191 ? 136.768 124.110 92.438  1.00 38.10  ? 191 SER B C   1 
ATOM 5947 O O   . SER D 4 191 ? 136.269 124.256 91.319  1.00 38.10  ? 191 SER B O   1 
ATOM 5948 C CB  . SER D 4 191 ? 135.089 123.527 94.208  1.00 38.10  ? 191 SER B CB  1 
ATOM 5949 O OG  . SER D 4 191 ? 135.815 122.480 94.829  1.00 38.10  ? 191 SER B OG  1 
ATOM 5950 N N   . LEU D 4 192 ? 137.948 123.533 92.643  1.00 38.87  ? 192 LEU B N   1 
ATOM 5951 C CA  . LEU D 4 192 ? 138.756 123.020 91.547  1.00 38.87  ? 192 LEU B CA  1 
ATOM 5952 C C   . LEU D 4 192 ? 138.633 121.505 91.454  1.00 38.87  ? 192 LEU B C   1 
ATOM 5953 O O   . LEU D 4 192 ? 138.601 120.807 92.471  1.00 38.87  ? 192 LEU B O   1 
ATOM 5954 C CB  . LEU D 4 192 ? 140.223 123.413 91.723  1.00 38.87  ? 192 LEU B CB  1 
ATOM 5955 C CG  . LEU D 4 192 ? 140.543 124.907 91.654  1.00 38.87  ? 192 LEU B CG  1 
ATOM 5956 C CD1 . LEU D 4 192 ? 141.838 125.211 92.388  1.00 38.87  ? 192 LEU B CD1 1 
ATOM 5957 C CD2 . LEU D 4 192 ? 140.621 125.367 90.208  1.00 38.87  ? 192 LEU B CD2 1 
ATOM 5958 N N   . ALA D 4 193 ? 138.562 121.005 90.223  1.00 47.97  ? 193 ALA B N   1 
ATOM 5959 C CA  . ALA D 4 193 ? 138.493 119.575 89.994  1.00 47.97  ? 193 ALA B CA  1 
ATOM 5960 C C   . ALA D 4 193 ? 139.835 118.922 90.318  1.00 47.97  ? 193 ALA B C   1 
ATOM 5961 O O   . ALA D 4 193 ? 140.879 119.578 90.288  1.00 47.97  ? 193 ALA B O   1 
ATOM 5962 C CB  . ALA D 4 193 ? 138.099 119.291 88.547  1.00 47.97  ? 193 ALA B CB  1 
ATOM 5963 N N   . PRO D 4 194 ? 139.829 117.626 90.649  1.00 51.97  ? 194 PRO B N   1 
ATOM 5964 C CA  . PRO D 4 194 ? 141.100 116.945 90.949  1.00 51.97  ? 194 PRO B CA  1 
ATOM 5965 C C   . PRO D 4 194 ? 142.103 116.989 89.809  1.00 51.97  ? 194 PRO B C   1 
ATOM 5966 O O   . PRO D 4 194 ? 143.313 117.026 90.064  1.00 51.97  ? 194 PRO B O   1 
ATOM 5967 C CB  . PRO D 4 194 ? 140.662 115.507 91.257  1.00 51.97  ? 194 PRO B CB  1 
ATOM 5968 C CG  . PRO D 4 194 ? 139.248 115.626 91.703  1.00 51.97  ? 194 PRO B CG  1 
ATOM 5969 C CD  . PRO D 4 194 ? 138.658 116.784 90.953  1.00 51.97  ? 194 PRO B CD  1 
ATOM 5970 N N   . ASP D 4 195 ? 141.644 116.986 88.558  1.00 55.80  ? 195 ASP B N   1 
ATOM 5971 C CA  . ASP D 4 195 ? 142.547 117.043 87.416  1.00 55.80  ? 195 ASP B CA  1 
ATOM 5972 C C   . ASP D 4 195 ? 142.991 118.461 87.080  1.00 55.80  ? 195 ASP B C   1 
ATOM 5973 O O   . ASP D 4 195 ? 143.804 118.634 86.165  1.00 55.80  ? 195 ASP B O   1 
ATOM 5974 C CB  . ASP D 4 195 ? 141.891 116.397 86.191  1.00 55.80  ? 195 ASP B CB  1 
ATOM 5975 C CG  . ASP D 4 195 ? 140.754 117.228 85.629  1.00 55.80  ? 195 ASP B CG  1 
ATOM 5976 O OD1 . ASP D 4 195 ? 140.072 117.919 86.414  1.00 55.80  ? 195 ASP B OD1 1 
ATOM 5977 O OD2 . ASP D 4 195 ? 140.539 117.186 84.399  1.00 55.80  ? 195 ASP B OD2 1 
ATOM 5978 N N   . THR D 4 196 ? 142.479 119.467 87.795  1.00 55.45  ? 196 THR B N   1 
ATOM 5979 C CA  . THR D 4 196 ? 142.869 120.868 87.611  1.00 55.45  ? 196 THR B CA  1 
ATOM 5980 C C   . THR D 4 196 ? 142.660 121.330 86.170  1.00 55.45  ? 196 THR B C   1 
ATOM 5981 O O   . THR D 4 196 ? 143.465 122.082 85.617  1.00 55.45  ? 196 THR B O   1 
ATOM 5982 C CB  . THR D 4 196 ? 144.317 121.107 88.051  1.00 55.45  ? 196 THR B CB  1 
ATOM 5983 O OG1 . THR D 4 196 ? 145.214 120.521 87.099  1.00 55.45  ? 196 THR B OG1 1 
ATOM 5984 C CG2 . THR D 4 196 ? 144.567 120.496 89.424  1.00 55.45  ? 196 THR B CG2 1 
ATOM 5985 N N   . ARG D 4 197 ? 141.567 120.877 85.555  1.00 55.21  ? 197 ARG B N   1 
ATOM 5986 C CA  . ARG D 4 197 ? 141.197 121.310 84.216  1.00 55.21  ? 197 ARG B CA  1 
ATOM 5987 C C   . ARG D 4 197 ? 139.831 121.974 84.142  1.00 55.21  ? 197 ARG B C   1 
ATOM 5988 O O   . ARG D 4 197 ? 139.590 122.741 83.203  1.00 55.21  ? 197 ARG B O   1 
ATOM 5989 C CB  . ARG D 4 197 ? 141.220 120.123 83.238  1.00 55.21  ? 197 ARG B CB  1 
ATOM 5990 N N   . LEU D 4 198 ? 138.940 121.711 85.096  1.00 47.67  ? 198 LEU B N   1 
ATOM 5991 C CA  . LEU D 4 198 ? 137.612 122.303 85.126  1.00 47.67  ? 198 LEU B CA  1 
ATOM 5992 C C   . LEU D 4 198 ? 137.357 122.843 86.525  1.00 47.67  ? 198 LEU B C   1 
ATOM 5993 O O   . LEU D 4 198 ? 137.944 122.376 87.504  1.00 47.67  ? 198 LEU B O   1 
ATOM 5994 C CB  . LEU D 4 198 ? 136.519 121.286 84.757  1.00 47.67  ? 198 LEU B CB  1 
ATOM 5995 C CG  . LEU D 4 198 ? 136.183 120.970 83.295  1.00 47.67  ? 198 LEU B CG  1 
ATOM 5996 C CD1 . LEU D 4 198 ? 135.635 122.200 82.589  1.00 47.67  ? 198 LEU B CD1 1 
ATOM 5997 C CD2 . LEU D 4 198 ? 137.366 120.378 82.536  1.00 47.67  ? 198 LEU B CD2 1 
ATOM 5998 N N   . PHE D 4 199 ? 136.477 123.838 86.618  1.00 44.98  ? 199 PHE B N   1 
ATOM 5999 C CA  . PHE D 4 199 ? 136.074 124.330 87.928  1.00 44.98  ? 199 PHE B CA  1 
ATOM 6000 C C   . PHE D 4 199 ? 134.667 124.904 87.853  1.00 44.98  ? 199 PHE B C   1 
ATOM 6001 O O   . PHE D 4 199 ? 134.342 125.654 86.930  1.00 44.98  ? 199 PHE B O   1 
ATOM 6002 C CB  . PHE D 4 199 ? 137.073 125.365 88.474  1.00 44.98  ? 199 PHE B CB  1 
ATOM 6003 C CG  . PHE D 4 199 ? 136.929 126.740 87.885  1.00 44.98  ? 199 PHE B CG  1 
ATOM 6004 C CD1 . PHE D 4 199 ? 137.528 127.055 86.677  1.00 44.98  ? 199 PHE B CD1 1 
ATOM 6005 C CD2 . PHE D 4 199 ? 136.214 127.724 88.550  1.00 44.98  ? 199 PHE B CD2 1 
ATOM 6006 C CE1 . PHE D 4 199 ? 137.408 128.322 86.138  1.00 44.98  ? 199 PHE B CE1 1 
ATOM 6007 C CE2 . PHE D 4 199 ? 136.088 128.991 88.013  1.00 44.98  ? 199 PHE B CE2 1 
ATOM 6008 C CZ  . PHE D 4 199 ? 136.685 129.290 86.806  1.00 44.98  ? 199 PHE B CZ  1 
ATOM 6009 N N   . VAL D 4 200 ? 133.835 124.539 88.824  1.00 43.21  ? 200 VAL B N   1 
ATOM 6010 C CA  . VAL D 4 200 ? 132.453 125.001 88.893  1.00 43.21  ? 200 VAL B CA  1 
ATOM 6011 C C   . VAL D 4 200 ? 132.343 126.042 89.997  1.00 43.21  ? 200 VAL B C   1 
ATOM 6012 O O   . VAL D 4 200 ? 132.956 125.906 91.063  1.00 43.21  ? 200 VAL B O   1 
ATOM 6013 C CB  . VAL D 4 200 ? 131.478 123.827 89.121  1.00 43.21  ? 200 VAL B CB  1 
ATOM 6014 C CG1 . VAL D 4 200 ? 131.726 123.157 90.466  1.00 43.21  ? 200 VAL B CG1 1 
ATOM 6015 C CG2 . VAL D 4 200 ? 130.034 124.299 89.009  1.00 43.21  ? 200 VAL B CG2 1 
ATOM 6016 N N   . SER D 4 201 ? 131.585 127.104 89.731  1.00 45.95  ? 201 SER B N   1 
ATOM 6017 C CA  . SER D 4 201 ? 131.438 128.193 90.684  1.00 45.95  ? 201 SER B CA  1 
ATOM 6018 C C   . SER D 4 201 ? 129.997 128.677 90.690  1.00 45.95  ? 201 SER B C   1 
ATOM 6019 O O   . SER D 4 201 ? 129.365 128.780 89.635  1.00 45.95  ? 201 SER B O   1 
ATOM 6020 C CB  . SER D 4 201 ? 132.386 129.349 90.352  1.00 45.95  ? 201 SER B CB  1 
ATOM 6021 O OG  . SER D 4 201 ? 132.314 130.358 91.339  1.00 45.95  ? 201 SER B OG  1 
ATOM 6022 N N   . GLY D 4 202 ? 129.485 128.977 91.883  1.00 44.93  ? 202 GLY B N   1 
ATOM 6023 C CA  . GLY D 4 202 ? 128.108 129.397 92.063  1.00 44.93  ? 202 GLY B CA  1 
ATOM 6024 C C   . GLY D 4 202 ? 128.006 130.879 92.370  1.00 44.93  ? 202 GLY B C   1 
ATOM 6025 O O   . GLY D 4 202 ? 128.907 131.467 92.976  1.00 44.93  ? 202 GLY B O   1 
ATOM 6026 N N   . ALA D 4 203 ? 126.894 131.482 91.958  1.00 48.87  ? 203 ALA B N   1 
ATOM 6027 C CA  . ALA D 4 203 ? 126.674 132.909 92.126  1.00 48.87  ? 203 ALA B CA  1 
ATOM 6028 C C   . ALA D 4 203 ? 125.381 133.160 92.893  1.00 48.87  ? 203 ALA B C   1 
ATOM 6029 O O   . ALA D 4 203 ? 124.629 132.238 93.217  1.00 48.87  ? 203 ALA B O   1 
ATOM 6030 C CB  . ALA D 4 203 ? 126.635 133.624 90.770  1.00 48.87  ? 203 ALA B CB  1 
ATOM 6031 N N   . CYS D 4 204 ? 125.132 134.440 93.184  1.00 52.22  ? 204 CYS B N   1 
ATOM 6032 C CA  . CYS D 4 204 ? 123.943 134.840 93.927  1.00 52.22  ? 204 CYS B CA  1 
ATOM 6033 C C   . CYS D 4 204 ? 122.660 134.710 93.118  1.00 52.22  ? 204 CYS B C   1 
ATOM 6034 O O   . CYS D 4 204 ? 121.573 134.821 93.694  1.00 52.22  ? 204 CYS B O   1 
ATOM 6035 C CB  . CYS D 4 204 ? 124.090 136.279 94.424  1.00 52.22  ? 204 CYS B CB  1 
ATOM 6036 S SG  . CYS D 4 204 ? 125.151 136.468 95.875  1.00 52.22  ? 204 CYS B SG  1 
ATOM 6037 N N   . ASP D 4 205 ? 122.754 134.479 91.809  1.00 52.80  ? 205 ASP B N   1 
ATOM 6038 C CA  . ASP D 4 205 ? 121.579 134.302 90.965  1.00 52.80  ? 205 ASP B CA  1 
ATOM 6039 C C   . ASP D 4 205 ? 121.039 132.877 90.997  1.00 52.80  ? 205 ASP B C   1 
ATOM 6040 O O   . ASP D 4 205 ? 120.309 132.487 90.076  1.00 52.80  ? 205 ASP B O   1 
ATOM 6041 C CB  . ASP D 4 205 ? 121.897 134.714 89.525  1.00 52.80  ? 205 ASP B CB  1 
ATOM 6042 C CG  . ASP D 4 205 ? 122.940 133.824 88.877  1.00 52.80  ? 205 ASP B CG  1 
ATOM 6043 O OD1 . ASP D 4 205 ? 123.674 133.128 89.610  1.00 52.80  ? 205 ASP B OD1 1 
ATOM 6044 O OD2 . ASP D 4 205 ? 123.026 133.820 87.631  1.00 52.80  ? 205 ASP B OD2 1 
ATOM 6045 N N   . ALA D 4 206 ? 121.388 132.105 92.029  1.00 52.15  ? 206 ALA B N   1 
ATOM 6046 C CA  . ALA D 4 206 ? 120.952 130.715 92.173  1.00 52.15  ? 206 ALA B CA  1 
ATOM 6047 C C   . ALA D 4 206 ? 121.364 129.874 90.968  1.00 52.15  ? 206 ALA B C   1 
ATOM 6048 O O   . ALA D 4 206 ? 120.603 129.035 90.482  1.00 52.15  ? 206 ALA B O   1 
ATOM 6049 C CB  . ALA D 4 206 ? 119.442 130.629 92.407  1.00 52.15  ? 206 ALA B CB  1 
ATOM 6050 N N   . SER D 4 207 ? 122.582 130.100 90.481  1.00 51.23  ? 207 SER B N   1 
ATOM 6051 C CA  . SER D 4 207 ? 123.096 129.354 89.343  1.00 51.23  ? 207 SER B CA  1 
ATOM 6052 C C   . SER D 4 207 ? 124.573 129.061 89.557  1.00 51.23  ? 207 SER B C   1 
ATOM 6053 O O   . SER D 4 207 ? 125.327 129.907 90.050  1.00 51.23  ? 207 SER B O   1 
ATOM 6054 C CB  . SER D 4 207 ? 122.894 130.116 88.028  1.00 51.23  ? 207 SER B CB  1 
ATOM 6055 O OG  . SER D 4 207 ? 123.902 131.096 87.847  1.00 51.23  ? 207 SER B OG  1 
ATOM 6056 N N   . ALA D 4 208 ? 124.979 127.854 89.170  1.00 49.79  ? 208 ALA B N   1 
ATOM 6057 C CA  . ALA D 4 208 ? 126.372 127.435 89.232  1.00 49.79  ? 208 ALA B CA  1 
ATOM 6058 C C   . ALA D 4 208 ? 126.837 127.065 87.833  1.00 49.79  ? 208 ALA B C   1 
ATOM 6059 O O   . ALA D 4 208 ? 126.237 126.205 87.185  1.00 49.79  ? 208 ALA B O   1 
ATOM 6060 C CB  . ALA D 4 208 ? 126.556 126.251 90.187  1.00 49.79  ? 208 ALA B CB  1 
ATOM 6061 N N   . LYS D 4 209 ? 127.908 127.702 87.375  1.00 50.39  ? 209 LYS B N   1 
ATOM 6062 C CA  . LYS D 4 209 ? 128.428 127.483 86.034  1.00 50.39  ? 209 LYS B CA  1 
ATOM 6063 C C   . LYS D 4 209 ? 129.775 126.779 86.097  1.00 50.39  ? 209 LYS B C   1 
ATOM 6064 O O   . LYS D 4 209 ? 130.586 127.041 86.993  1.00 50.39  ? 209 LYS B O   1 
ATOM 6065 C CB  . LYS D 4 209 ? 128.564 128.803 85.270  1.00 50.39  ? 209 LYS B CB  1 
ATOM 6066 C CG  . LYS D 4 209 ? 127.309 129.659 85.277  1.00 50.39  ? 209 LYS B CG  1 
ATOM 6067 C CD  . LYS D 4 209 ? 127.448 130.849 84.340  1.00 50.39  ? 209 LYS B CD  1 
ATOM 6068 C CE  . LYS D 4 209 ? 126.771 130.588 83.006  1.00 50.39  ? 209 LYS B CE  1 
ATOM 6069 N NZ  . LYS D 4 209 ? 125.288 130.652 83.115  1.00 50.39  ? 209 LYS B NZ  1 
ATOM 6070 N N   . LEU D 4 210 ? 130.003 125.879 85.144  1.00 53.23  ? 210 LEU B N   1 
ATOM 6071 C CA  . LEU D 4 210 ? 131.265 125.165 85.016  1.00 53.23  ? 210 LEU B CA  1 
ATOM 6072 C C   . LEU D 4 210 ? 132.114 125.835 83.945  1.00 53.23  ? 210 LEU B C   1 
ATOM 6073 O O   . LEU D 4 210 ? 131.632 126.098 82.838  1.00 53.23  ? 210 LEU B O   1 
ATOM 6074 C CB  . LEU D 4 210 ? 131.029 123.695 84.666  1.00 53.23  ? 210 LEU B CB  1 
ATOM 6075 C CG  . LEU D 4 210 ? 132.267 122.877 84.294  1.00 53.23  ? 210 LEU B CG  1 
ATOM 6076 C CD1 . LEU D 4 210 ? 132.946 122.333 85.541  1.00 53.23  ? 210 LEU B CD1 1 
ATOM 6077 C CD2 . LEU D 4 210 ? 131.900 121.749 83.344  1.00 53.23  ? 210 LEU B CD2 1 
ATOM 6078 N N   . TRP D 4 211 ? 133.373 126.109 84.275  1.00 50.32  ? 211 TRP B N   1 
ATOM 6079 C CA  . TRP D 4 211 ? 134.300 126.789 83.387  1.00 50.32  ? 211 TRP B CA  1 
ATOM 6080 C C   . TRP D 4 211 ? 135.517 125.909 83.143  1.00 50.32  ? 211 TRP B C   1 
ATOM 6081 O O   . TRP D 4 211 ? 135.957 125.170 84.035  1.00 50.32  ? 211 TRP B O   1 
ATOM 6082 C CB  . TRP D 4 211 ? 134.746 128.131 83.976  1.00 50.32  ? 211 TRP B CB  1 
ATOM 6083 C CG  . TRP D 4 211 ? 133.656 128.896 84.663  1.00 50.32  ? 211 TRP B CG  1 
ATOM 6084 C CD1 . TRP D 4 211 ? 133.276 128.786 85.969  1.00 50.32  ? 211 TRP B CD1 1 
ATOM 6085 C CD2 . TRP D 4 211 ? 132.829 129.916 84.090  1.00 50.32  ? 211 TRP B CD2 1 
ATOM 6086 N NE1 . TRP D 4 211 ? 132.251 129.660 86.240  1.00 50.32  ? 211 TRP B NE1 1 
ATOM 6087 C CE2 . TRP D 4 211 ? 131.960 130.367 85.103  1.00 50.32  ? 211 TRP B CE2 1 
ATOM 6088 C CE3 . TRP D 4 211 ? 132.734 130.486 82.817  1.00 50.32  ? 211 TRP B CE3 1 
ATOM 6089 C CZ2 . TRP D 4 211 ? 131.009 131.360 84.883  1.00 50.32  ? 211 TRP B CZ2 1 
ATOM 6090 C CZ3 . TRP D 4 211 ? 131.789 131.473 82.601  1.00 50.32  ? 211 TRP B CZ3 1 
ATOM 6091 C CH2 . TRP D 4 211 ? 130.939 131.899 83.628  1.00 50.32  ? 211 TRP B CH2 1 
ATOM 6092 N N   . ASP D 4 212 ? 136.056 125.996 81.930  1.00 56.72  ? 212 ASP B N   1 
ATOM 6093 C CA  . ASP D 4 212 ? 137.265 125.278 81.556  1.00 56.72  ? 212 ASP B CA  1 
ATOM 6094 C C   . ASP D 4 212 ? 138.465 126.204 81.701  1.00 56.72  ? 212 ASP B C   1 
ATOM 6095 O O   . ASP D 4 212 ? 138.452 127.331 81.195  1.00 56.72  ? 212 ASP B O   1 
ATOM 6096 C CB  . ASP D 4 212 ? 137.160 124.757 80.122  1.00 56.72  ? 212 ASP B CB  1 
ATOM 6097 C CG  . ASP D 4 212 ? 138.287 123.808 79.760  1.00 56.72  ? 212 ASP B CG  1 
ATOM 6098 O OD1 . ASP D 4 212 ? 139.434 124.275 79.593  1.00 56.72  ? 212 ASP B OD1 1 
ATOM 6099 O OD2 . ASP D 4 212 ? 138.026 122.593 79.639  1.00 56.72  ? 212 ASP B OD2 1 
ATOM 6100 N N   . VAL D 4 213 ? 139.495 125.728 82.401  1.00 57.34  ? 213 VAL B N   1 
ATOM 6101 C CA  . VAL D 4 213 ? 140.678 126.550 82.638  1.00 57.34  ? 213 VAL B CA  1 
ATOM 6102 C C   . VAL D 4 213 ? 141.400 126.840 81.328  1.00 57.34  ? 213 VAL B C   1 
ATOM 6103 O O   . VAL D 4 213 ? 141.764 127.987 81.041  1.00 57.34  ? 213 VAL B O   1 
ATOM 6104 C CB  . VAL D 4 213 ? 141.607 125.865 83.656  1.00 57.34  ? 213 VAL B CB  1 
ATOM 6105 C CG1 . VAL D 4 213 ? 142.732 126.801 84.062  1.00 57.34  ? 213 VAL B CG1 1 
ATOM 6106 C CG2 . VAL D 4 213 ? 140.815 125.413 84.874  1.00 57.34  ? 213 VAL B CG2 1 
ATOM 6107 N N   . ARG D 4 214 ? 141.618 125.806 80.512  1.00 60.09  ? 214 ARG B N   1 
ATOM 6108 C CA  . ARG D 4 214 ? 142.338 125.996 79.256  1.00 60.09  ? 214 ARG B CA  1 
ATOM 6109 C C   . ARG D 4 214 ? 141.482 126.720 78.224  1.00 60.09  ? 214 ARG B C   1 
ATOM 6110 O O   . ARG D 4 214 ? 141.961 127.636 77.546  1.00 60.09  ? 214 ARG B O   1 
ATOM 6111 C CB  . ARG D 4 214 ? 142.807 124.647 78.713  1.00 60.09  ? 214 ARG B CB  1 
ATOM 6112 N N   . GLU D 4 215 ? 140.214 126.324 78.088  1.00 60.55  ? 215 GLU B N   1 
ATOM 6113 C CA  . GLU D 4 215 ? 139.360 126.923 77.067  1.00 60.55  ? 215 GLU B CA  1 
ATOM 6114 C C   . GLU D 4 215 ? 138.937 128.335 77.452  1.00 60.55  ? 215 GLU B C   1 
ATOM 6115 O O   . GLU D 4 215 ? 138.931 129.239 76.608  1.00 60.55  ? 215 GLU B O   1 
ATOM 6116 C CB  . GLU D 4 215 ? 138.135 126.042 76.824  1.00 60.55  ? 215 GLU B CB  1 
ATOM 6117 N N   . GLY D 4 216 ? 138.580 128.546 78.717  1.00 62.08  ? 216 GLY B N   1 
ATOM 6118 C CA  . GLY D 4 216 ? 138.137 129.848 79.166  1.00 62.08  ? 216 GLY B CA  1 
ATOM 6119 C C   . GLY D 4 216 ? 136.695 130.182 78.862  1.00 62.08  ? 216 GLY B C   1 
ATOM 6120 O O   . GLY D 4 216 ? 136.309 131.349 78.988  1.00 62.08  ? 216 GLY B O   1 
ATOM 6121 N N   . MET D 4 217 ? 135.887 129.201 78.468  1.00 61.05  ? 217 MET B N   1 
ATOM 6122 C CA  . MET D 4 217 ? 134.489 129.424 78.130  1.00 61.05  ? 217 MET B CA  1 
ATOM 6123 C C   . MET D 4 217 ? 133.605 128.499 78.953  1.00 61.05  ? 217 MET B C   1 
ATOM 6124 O O   . MET D 4 217 ? 134.000 127.385 79.305  1.00 61.05  ? 217 MET B O   1 
ATOM 6125 C CB  . MET D 4 217 ? 134.229 129.199 76.634  1.00 61.05  ? 217 MET B CB  1 
ATOM 6126 N N   . CYS D 4 218 ? 132.401 128.977 79.257  1.00 64.16  ? 218 CYS B N   1 
ATOM 6127 C CA  . CYS D 4 218 ? 131.454 128.193 80.036  1.00 64.16  ? 218 CYS B CA  1 
ATOM 6128 C C   . CYS D 4 218 ? 130.895 127.041 79.208  1.00 64.16  ? 218 CYS B C   1 
ATOM 6129 O O   . CYS D 4 218 ? 130.686 127.158 77.997  1.00 64.16  ? 218 CYS B O   1 
ATOM 6130 C CB  . CYS D 4 218 ? 130.312 129.076 80.536  1.00 64.16  ? 218 CYS B CB  1 
ATOM 6131 S SG  . CYS D 4 218 ? 128.992 128.179 81.384  1.00 64.16  ? 218 CYS B SG  1 
ATOM 6132 N N   . ARG D 4 219 ? 130.650 125.917 79.878  1.00 63.81  ? 219 ARG B N   1 
ATOM 6133 C CA  . ARG D 4 219 ? 130.107 124.729 79.232  1.00 63.81  ? 219 ARG B CA  1 
ATOM 6134 C C   . ARG D 4 219 ? 128.729 124.354 79.753  1.00 63.81  ? 219 ARG B C   1 
ATOM 6135 O O   . ARG D 4 219 ? 127.810 124.136 78.956  1.00 63.81  ? 219 ARG B O   1 
ATOM 6136 C CB  . ARG D 4 219 ? 131.070 123.544 79.406  1.00 63.81  ? 219 ARG B CB  1 
ATOM 6137 C CG  . ARG D 4 219 ? 132.532 123.936 79.509  1.00 63.81  ? 219 ARG B CG  1 
ATOM 6138 C CD  . ARG D 4 219 ? 133.396 122.724 79.809  1.00 63.81  ? 219 ARG B CD  1 
ATOM 6139 N NE  . ARG D 4 219 ? 133.220 121.667 78.821  1.00 63.81  ? 219 ARG B NE  1 
ATOM 6140 C CZ  . ARG D 4 219 ? 133.791 121.654 77.624  1.00 63.81  ? 219 ARG B CZ  1 
ATOM 6141 N NH1 . ARG D 4 219 ? 134.595 122.629 77.231  1.00 63.81  ? 219 ARG B NH1 1 
ATOM 6142 N NH2 . ARG D 4 219 ? 133.551 120.637 76.802  1.00 63.81  ? 219 ARG B NH2 1 
ATOM 6143 N N   . GLN D 4 220 ? 128.556 124.269 81.071  1.00 61.71  ? 220 GLN B N   1 
ATOM 6144 C CA  . GLN D 4 220 ? 127.300 123.833 81.660  1.00 61.71  ? 220 GLN B CA  1 
ATOM 6145 C C   . GLN D 4 220 ? 126.860 124.803 82.747  1.00 61.71  ? 220 GLN B C   1 
ATOM 6146 O O   . GLN D 4 220 ? 127.684 125.419 83.430  1.00 61.71  ? 220 GLN B O   1 
ATOM 6147 C CB  . GLN D 4 220 ? 127.416 122.419 82.244  1.00 61.71  ? 220 GLN B CB  1 
ATOM 6148 C CG  . GLN D 4 220 ? 127.635 121.334 81.203  1.00 61.71  ? 220 GLN B CG  1 
ATOM 6149 C CD  . GLN D 4 220 ? 128.350 120.122 81.766  1.00 61.71  ? 220 GLN B CD  1 
ATOM 6150 O OE1 . GLN D 4 220 ? 129.442 119.769 81.322  1.00 61.71  ? 220 GLN B OE1 1 
ATOM 6151 N NE2 . GLN D 4 220 ? 127.735 119.478 82.750  1.00 61.71  ? 220 GLN B NE2 1 
ATOM 6152 N N   . THR D 4 221 ? 125.542 124.930 82.893  1.00 57.36  ? 221 THR B N   1 
ATOM 6153 C CA  . THR D 4 221 ? 124.925 125.767 83.911  1.00 57.36  ? 221 THR B CA  1 
ATOM 6154 C C   . THR D 4 221 ? 123.887 124.948 84.663  1.00 57.36  ? 221 THR B C   1 
ATOM 6155 O O   . THR D 4 221 ? 123.089 124.230 84.053  1.00 57.36  ? 221 THR B O   1 
ATOM 6156 C CB  . THR D 4 221 ? 124.268 127.010 83.295  1.00 57.36  ? 221 THR B CB  1 
ATOM 6157 O OG1 . THR D 4 221 ? 125.240 127.738 82.535  1.00 57.36  ? 221 THR B OG1 1 
ATOM 6158 C CG2 . THR D 4 221 ? 123.705 127.913 84.381  1.00 57.36  ? 221 THR B CG2 1 
ATOM 6159 N N   . PHE D 4 222 ? 123.901 125.058 85.989  1.00 55.91  ? 222 PHE B N   1 
ATOM 6160 C CA  . PHE D 4 222 ? 123.018 124.300 86.862  1.00 55.91  ? 222 PHE B CA  1 
ATOM 6161 C C   . PHE D 4 222 ? 122.188 125.269 87.690  1.00 55.91  ? 222 PHE B C   1 
ATOM 6162 O O   . PHE D 4 222 ? 122.736 126.184 88.317  1.00 55.91  ? 222 PHE B O   1 
ATOM 6163 C CB  . PHE D 4 222 ? 123.817 123.369 87.779  1.00 55.91  ? 222 PHE B CB  1 
ATOM 6164 C CG  . PHE D 4 222 ? 124.798 122.492 87.051  1.00 55.91  ? 222 PHE B CG  1 
ATOM 6165 C CD1 . PHE D 4 222 ? 126.074 122.949 86.759  1.00 55.91  ? 222 PHE B CD1 1 
ATOM 6166 C CD2 . PHE D 4 222 ? 124.448 121.211 86.664  1.00 55.91  ? 222 PHE B CD2 1 
ATOM 6167 C CE1 . PHE D 4 222 ? 126.978 122.145 86.091  1.00 55.91  ? 222 PHE B CE1 1 
ATOM 6168 C CE2 . PHE D 4 222 ? 125.348 120.403 85.998  1.00 55.91  ? 222 PHE B CE2 1 
ATOM 6169 C CZ  . PHE D 4 222 ? 126.614 120.871 85.711  1.00 55.91  ? 222 PHE B CZ  1 
ATOM 6170 N N   . THR D 4 223 ? 120.873 125.065 87.690  1.00 57.93  ? 223 THR B N   1 
ATOM 6171 C CA  . THR D 4 223 ? 119.933 125.889 88.435  1.00 57.93  ? 223 THR B CA  1 
ATOM 6172 C C   . THR D 4 223 ? 118.994 124.982 89.223  1.00 57.93  ? 223 THR B C   1 
ATOM 6173 O O   . THR D 4 223 ? 119.038 123.753 89.109  1.00 57.93  ? 223 THR B O   1 
ATOM 6174 C CB  . THR D 4 223 ? 119.140 126.815 87.504  1.00 57.93  ? 223 THR B CB  1 
ATOM 6175 O OG1 . THR D 4 223 ? 118.603 126.054 86.414  1.00 57.93  ? 223 THR B OG1 1 
ATOM 6176 C CG2 . THR D 4 223 ? 120.033 127.918 86.956  1.00 57.93  ? 223 THR B CG2 1 
ATOM 6177 N N   . GLY D 4 224 ? 118.136 125.599 90.030  1.00 58.13  ? 224 GLY B N   1 
ATOM 6178 C CA  . GLY D 4 224 ? 117.183 124.855 90.829  1.00 58.13  ? 224 GLY B CA  1 
ATOM 6179 C C   . GLY D 4 224 ? 117.024 125.409 92.229  1.00 58.13  ? 224 GLY B C   1 
ATOM 6180 O O   . GLY D 4 224 ? 116.039 125.116 92.913  1.00 58.13  ? 224 GLY B O   1 
ATOM 6181 N N   . HIS D 4 225 ? 117.988 126.213 92.664  1.00 54.37  ? 225 HIS B N   1 
ATOM 6182 C CA  . HIS D 4 225 ? 117.948 126.825 93.981  1.00 54.37  ? 225 HIS B CA  1 
ATOM 6183 C C   . HIS D 4 225 ? 117.024 128.037 93.978  1.00 54.37  ? 225 HIS B C   1 
ATOM 6184 O O   . HIS D 4 225 ? 116.885 128.735 92.970  1.00 54.37  ? 225 HIS B O   1 
ATOM 6185 C CB  . HIS D 4 225 ? 119.351 127.239 94.428  1.00 54.37  ? 225 HIS B CB  1 
ATOM 6186 C CG  . HIS D 4 225 ? 120.130 126.133 95.070  1.00 54.37  ? 225 HIS B CG  1 
ATOM 6187 N ND1 . HIS D 4 225 ? 119.713 125.499 96.220  1.00 54.37  ? 225 HIS B ND1 1 
ATOM 6188 C CD2 . HIS D 4 225 ? 121.300 125.548 94.721  1.00 54.37  ? 225 HIS B CD2 1 
ATOM 6189 C CE1 . HIS D 4 225 ? 120.595 124.574 96.555  1.00 54.37  ? 225 HIS B CE1 1 
ATOM 6190 N NE2 . HIS D 4 225 ? 121.567 124.582 95.661  1.00 54.37  ? 225 HIS B NE2 1 
ATOM 6191 N N   . GLU D 4 226 ? 116.385 128.275 95.120  1.00 61.75  ? 226 GLU B N   1 
ATOM 6192 C CA  . GLU D 4 226 ? 115.469 129.395 95.285  1.00 61.75  ? 226 GLU B CA  1 
ATOM 6193 C C   . GLU D 4 226 ? 116.111 130.593 95.971  1.00 61.75  ? 226 GLU B C   1 
ATOM 6194 O O   . GLU D 4 226 ? 115.414 131.573 96.253  1.00 61.75  ? 226 GLU B O   1 
ATOM 6195 C CB  . GLU D 4 226 ? 114.230 128.953 96.072  1.00 61.75  ? 226 GLU B CB  1 
ATOM 6196 C CG  . GLU D 4 226 ? 113.567 127.693 95.538  1.00 61.75  ? 226 GLU B CG  1 
ATOM 6197 C CD  . GLU D 4 226 ? 114.084 126.433 96.203  1.00 61.75  ? 226 GLU B CD  1 
ATOM 6198 O OE1 . GLU D 4 226 ? 114.333 126.464 97.427  1.00 61.75  ? 226 GLU B OE1 1 
ATOM 6199 O OE2 . GLU D 4 226 ? 114.243 125.411 95.503  1.00 61.75  ? 226 GLU B OE2 1 
ATOM 6200 N N   . SER D 4 227 ? 117.411 130.543 96.246  1.00 56.76  ? 227 SER B N   1 
ATOM 6201 C CA  . SER D 4 227 ? 118.099 131.635 96.920  1.00 56.76  ? 227 SER B CA  1 
ATOM 6202 C C   . SER D 4 227 ? 119.575 131.588 96.539  1.00 56.76  ? 227 SER B C   1 
ATOM 6203 O O   . SER D 4 227 ? 119.975 130.865 95.622  1.00 56.76  ? 227 SER B O   1 
ATOM 6204 C CB  . SER D 4 227 ? 117.889 131.552 98.438  1.00 56.76  ? 227 SER B CB  1 
ATOM 6205 O OG  . SER D 4 227 ? 118.663 130.508 99.003  1.00 56.76  ? 227 SER B OG  1 
ATOM 6206 N N   . ASP D 4 228 ? 120.385 132.368 97.250  1.00 52.30  ? 228 ASP B N   1 
ATOM 6207 C CA  . ASP D 4 228 ? 121.814 132.426 96.979  1.00 52.30  ? 228 ASP B CA  1 
ATOM 6208 C C   . ASP D 4 228 ? 122.480 131.089 97.281  1.00 52.30  ? 228 ASP B C   1 
ATOM 6209 O O   . ASP D 4 228 ? 122.106 130.387 98.224  1.00 52.30  ? 228 ASP B O   1 
ATOM 6210 C CB  . ASP D 4 228 ? 122.461 133.534 97.812  1.00 52.30  ? 228 ASP B CB  1 
ATOM 6211 C CG  . ASP D 4 228 ? 123.949 133.684 97.541  1.00 52.30  ? 228 ASP B CG  1 
ATOM 6212 O OD1 . ASP D 4 228 ? 124.447 133.107 96.551  1.00 52.30  ? 228 ASP B OD1 1 
ATOM 6213 O OD2 . ASP D 4 228 ? 124.625 134.381 98.326  1.00 52.30  ? 228 ASP B OD2 1 
ATOM 6214 N N   . ILE D 4 229 ? 123.476 130.743 96.470  1.00 47.11  ? 229 ILE B N   1 
ATOM 6215 C CA  . ILE D 4 229 ? 124.300 129.559 96.681  1.00 47.11  ? 229 ILE B CA  1 
ATOM 6216 C C   . ILE D 4 229 ? 125.583 130.008 97.363  1.00 47.11  ? 229 ILE B C   1 
ATOM 6217 O O   . ILE D 4 229 ? 126.355 130.789 96.795  1.00 47.11  ? 229 ILE B O   1 
ATOM 6218 C CB  . ILE D 4 229 ? 124.600 128.838 95.357  1.00 47.11  ? 229 ILE B CB  1 
ATOM 6219 C CG1 . ILE D 4 229 ? 123.302 128.374 94.696  1.00 47.11  ? 229 ILE B CG1 1 
ATOM 6220 C CG2 . ILE D 4 229 ? 125.536 127.662 95.591  1.00 47.11  ? 229 ILE B CG2 1 
ATOM 6221 C CD1 . ILE D 4 229 ? 123.451 128.050 93.226  1.00 47.11  ? 229 ILE B CD1 1 
ATOM 6222 N N   . ASN D 4 230 ? 125.817 129.516 98.579  1.00 46.17  ? 230 ASN B N   1 
ATOM 6223 C CA  . ASN D 4 230 ? 126.922 130.002 99.397  1.00 46.17  ? 230 ASN B CA  1 
ATOM 6224 C C   . ASN D 4 230 ? 128.164 129.126 99.340  1.00 46.17  ? 230 ASN B C   1 
ATOM 6225 O O   . ASN D 4 230 ? 129.272 129.636 99.534  1.00 46.17  ? 230 ASN B O   1 
ATOM 6226 C CB  . ASN D 4 230 ? 126.477 130.136 100.857 1.00 46.17  ? 230 ASN B CB  1 
ATOM 6227 C CG  . ASN D 4 230 ? 125.306 131.083 101.025 1.00 46.17  ? 230 ASN B CG  1 
ATOM 6228 O OD1 . ASN D 4 230 ? 124.323 130.760 101.692 1.00 46.17  ? 230 ASN B OD1 1 
ATOM 6229 N ND2 . ASN D 4 230 ? 125.405 132.260 100.420 1.00 46.17  ? 230 ASN B ND2 1 
ATOM 6230 N N   . ALA D 4 231 ? 128.019 127.828 99.082  1.00 39.22  ? 231 ALA B N   1 
ATOM 6231 C CA  . ALA D 4 231 ? 129.151 126.914 99.119  1.00 39.22  ? 231 ALA B CA  1 
ATOM 6232 C C   . ALA D 4 231 ? 129.083 125.956 97.939  1.00 39.22  ? 231 ALA B C   1 
ATOM 6233 O O   . ALA D 4 231 ? 128.017 125.707 97.371  1.00 39.22  ? 231 ALA B O   1 
ATOM 6234 C CB  . ALA D 4 231 ? 129.197 126.133 100.438 1.00 39.22  ? 231 ALA B CB  1 
ATOM 6235 N N   . ILE D 4 232 ? 130.248 125.416 97.579  1.00 40.62  ? 232 ILE B N   1 
ATOM 6236 C CA  . ILE D 4 232 ? 130.371 124.483 96.466  1.00 40.62  ? 232 ILE B CA  1 
ATOM 6237 C C   . ILE D 4 232 ? 131.599 123.614 96.704  1.00 40.62  ? 232 ILE B C   1 
ATOM 6238 O O   . ILE D 4 232 ? 132.563 124.035 97.350  1.00 40.62  ? 232 ILE B O   1 
ATOM 6239 C CB  . ILE D 4 232 ? 130.450 125.228 95.110  1.00 40.62  ? 232 ILE B CB  1 
ATOM 6240 C CG1 . ILE D 4 232 ? 130.039 124.309 93.960  1.00 40.62  ? 232 ILE B CG1 1 
ATOM 6241 C CG2 . ILE D 4 232 ? 131.843 125.790 94.877  1.00 40.62  ? 232 ILE B CG2 1 
ATOM 6242 C CD1 . ILE D 4 232 ? 129.602 125.056 92.720  1.00 40.62  ? 232 ILE B CD1 1 
ATOM 6243 N N   . CYS D 4 233 ? 131.552 122.384 96.191  1.00 39.74  ? 233 CYS B N   1 
ATOM 6244 C CA  . CYS D 4 233 ? 132.650 121.440 96.365  1.00 39.74  ? 233 CYS B CA  1 
ATOM 6245 C C   . CYS D 4 233 ? 132.473 120.281 95.396  1.00 39.74  ? 233 CYS B C   1 
ATOM 6246 O O   . CYS D 4 233 ? 131.385 119.703 95.315  1.00 39.74  ? 233 CYS B O   1 
ATOM 6247 C CB  . CYS D 4 233 ? 132.709 120.921 97.807  1.00 39.74  ? 233 CYS B CB  1 
ATOM 6248 S SG  . CYS D 4 233 ? 134.112 119.836 98.156  1.00 39.74  ? 233 CYS B SG  1 
ATOM 6249 N N   . PHE D 4 234 ? 133.539 119.943 94.674  1.00 41.94  ? 234 PHE B N   1 
ATOM 6250 C CA  . PHE D 4 234 ? 133.508 118.805 93.765  1.00 41.94  ? 234 PHE B CA  1 
ATOM 6251 C C   . PHE D 4 234 ? 133.458 117.483 94.523  1.00 41.94  ? 234 PHE B C   1 
ATOM 6252 O O   . PHE D 4 234 ? 133.923 117.369 95.660  1.00 41.94  ? 234 PHE B O   1 
ATOM 6253 C CB  . PHE D 4 234 ? 134.733 118.804 92.850  1.00 41.94  ? 234 PHE B CB  1 
ATOM 6254 C CG  . PHE D 4 234 ? 134.578 119.637 91.611  1.00 41.94  ? 234 PHE B CG  1 
ATOM 6255 C CD1 . PHE D 4 234 ? 133.898 119.137 90.513  1.00 41.94  ? 234 PHE B CD1 1 
ATOM 6256 C CD2 . PHE D 4 234 ? 135.130 120.902 91.530  1.00 41.94  ? 234 PHE B CD2 1 
ATOM 6257 C CE1 . PHE D 4 234 ? 133.758 119.888 89.363  1.00 41.94  ? 234 PHE B CE1 1 
ATOM 6258 C CE2 . PHE D 4 234 ? 134.993 121.658 90.381  1.00 41.94  ? 234 PHE B CE2 1 
ATOM 6259 C CZ  . PHE D 4 234 ? 134.308 121.149 89.297  1.00 41.94  ? 234 PHE B CZ  1 
ATOM 6260 N N   . PHE D 4 235 ? 132.882 116.478 93.870  1.00 47.70  ? 235 PHE B N   1 
ATOM 6261 C CA  . PHE D 4 235 ? 133.015 115.107 94.329  1.00 47.70  ? 235 PHE B CA  1 
ATOM 6262 C C   . PHE D 4 235 ? 134.466 114.656 94.160  1.00 47.70  ? 235 PHE B C   1 
ATOM 6263 O O   . PHE D 4 235 ? 135.184 115.171 93.298  1.00 47.70  ? 235 PHE B O   1 
ATOM 6264 C CB  . PHE D 4 235 ? 132.081 114.193 93.538  1.00 47.70  ? 235 PHE B CB  1 
ATOM 6265 C CG  . PHE D 4 235 ? 131.565 113.016 94.318  1.00 47.70  ? 235 PHE B CG  1 
ATOM 6266 C CD1 . PHE D 4 235 ? 130.596 113.185 95.292  1.00 47.70  ? 235 PHE B CD1 1 
ATOM 6267 C CD2 . PHE D 4 235 ? 132.037 111.739 94.065  1.00 47.70  ? 235 PHE B CD2 1 
ATOM 6268 C CE1 . PHE D 4 235 ? 130.117 112.103 96.007  1.00 47.70  ? 235 PHE B CE1 1 
ATOM 6269 C CE2 . PHE D 4 235 ? 131.563 110.654 94.777  1.00 47.70  ? 235 PHE B CE2 1 
ATOM 6270 C CZ  . PHE D 4 235 ? 130.601 110.837 95.748  1.00 47.70  ? 235 PHE B CZ  1 
ATOM 6271 N N   . PRO D 4 236 ? 134.929 113.710 94.982  1.00 50.83  ? 236 PRO B N   1 
ATOM 6272 C CA  . PRO D 4 236 ? 136.319 113.241 94.839  1.00 50.83  ? 236 PRO B CA  1 
ATOM 6273 C C   . PRO D 4 236 ? 136.648 112.707 93.455  1.00 50.83  ? 236 PRO B C   1 
ATOM 6274 O O   . PRO D 4 236 ? 137.789 112.861 93.002  1.00 50.83  ? 236 PRO B O   1 
ATOM 6275 C CB  . PRO D 4 236 ? 136.438 112.145 95.910  1.00 50.83  ? 236 PRO B CB  1 
ATOM 6276 C CG  . PRO D 4 236 ? 135.050 111.941 96.458  1.00 50.83  ? 236 PRO B CG  1 
ATOM 6277 C CD  . PRO D 4 236 ? 134.311 113.210 96.219  1.00 50.83  ? 236 PRO B CD  1 
ATOM 6278 N N   . ASN D 4 237 ? 135.690 112.083 92.764  1.00 52.41  ? 237 ASN B N   1 
ATOM 6279 C CA  . ASN D 4 237 ? 135.955 111.610 91.411  1.00 52.41  ? 237 ASN B CA  1 
ATOM 6280 C C   . ASN D 4 237 ? 135.980 112.746 90.395  1.00 52.41  ? 237 ASN B C   1 
ATOM 6281 O O   . ASN D 4 237 ? 136.524 112.568 89.300  1.00 52.41  ? 237 ASN B O   1 
ATOM 6282 C CB  . ASN D 4 237 ? 134.918 110.560 91.000  1.00 52.41  ? 237 ASN B CB  1 
ATOM 6283 C CG  . ASN D 4 237 ? 133.525 111.141 90.831  1.00 52.41  ? 237 ASN B CG  1 
ATOM 6284 O OD1 . ASN D 4 237 ? 133.243 112.257 91.263  1.00 52.41  ? 237 ASN B OD1 1 
ATOM 6285 N ND2 . ASN D 4 237 ? 132.644 110.378 90.194  1.00 52.41  ? 237 ASN B ND2 1 
ATOM 6286 N N   . GLY D 4 238 ? 135.409 113.901 90.732  1.00 50.54  ? 238 GLY B N   1 
ATOM 6287 C CA  . GLY D 4 238 ? 135.394 115.044 89.845  1.00 50.54  ? 238 GLY B CA  1 
ATOM 6288 C C   . GLY D 4 238 ? 134.231 115.106 88.879  1.00 50.54  ? 238 GLY B C   1 
ATOM 6289 O O   . GLY D 4 238 ? 134.162 116.050 88.083  1.00 50.54  ? 238 GLY B O   1 
ATOM 6290 N N   . ASN D 4 239 ? 133.318 114.137 88.919  1.00 54.76  ? 239 ASN B N   1 
ATOM 6291 C CA  . ASN D 4 239 ? 132.179 114.096 88.013  1.00 54.76  ? 239 ASN B CA  1 
ATOM 6292 C C   . ASN D 4 239 ? 130.902 114.646 88.637  1.00 54.76  ? 239 ASN B C   1 
ATOM 6293 O O   . ASN D 4 239 ? 129.841 114.582 88.009  1.00 54.76  ? 239 ASN B O   1 
ATOM 6294 C CB  . ASN D 4 239 ? 131.945 112.664 87.526  1.00 54.76  ? 239 ASN B CB  1 
ATOM 6295 C CG  . ASN D 4 239 ? 133.138 112.101 86.779  1.00 54.76  ? 239 ASN B CG  1 
ATOM 6296 O OD1 . ASN D 4 239 ? 133.909 112.841 86.169  1.00 54.76  ? 239 ASN B OD1 1 
ATOM 6297 N ND2 . ASN D 4 239 ? 133.295 110.783 86.824  1.00 54.76  ? 239 ASN B ND2 1 
ATOM 6298 N N   . ALA D 4 240 ? 130.977 115.185 89.852  1.00 47.61  ? 240 ALA B N   1 
ATOM 6299 C CA  . ALA D 4 240 ? 129.797 115.710 90.523  1.00 47.61  ? 240 ALA B CA  1 
ATOM 6300 C C   . ALA D 4 240 ? 130.228 116.772 91.523  1.00 47.61  ? 240 ALA B C   1 
ATOM 6301 O O   . ALA D 4 240 ? 131.401 116.866 91.890  1.00 47.61  ? 240 ALA B O   1 
ATOM 6302 C CB  . ALA D 4 240 ? 129.004 114.600 91.221  1.00 47.61  ? 240 ALA B CB  1 
ATOM 6303 N N   . PHE D 4 241 ? 129.259 117.577 91.953  1.00 45.80  ? 241 PHE B N   1 
ATOM 6304 C CA  . PHE D 4 241 ? 129.522 118.614 92.941  1.00 45.80  ? 241 PHE B CA  1 
ATOM 6305 C C   . PHE D 4 241 ? 128.249 118.926 93.716  1.00 45.80  ? 241 PHE B C   1 
ATOM 6306 O O   . PHE D 4 241 ? 127.140 118.838 93.184  1.00 45.80  ? 241 PHE B O   1 
ATOM 6307 C CB  . PHE D 4 241 ? 130.082 119.887 92.288  1.00 45.80  ? 241 PHE B CB  1 
ATOM 6308 C CG  . PHE D 4 241 ? 129.094 120.617 91.423  1.00 45.80  ? 241 PHE B CG  1 
ATOM 6309 C CD1 . PHE D 4 241 ? 128.887 120.232 90.110  1.00 45.80  ? 241 PHE B CD1 1 
ATOM 6310 C CD2 . PHE D 4 241 ? 128.384 121.698 91.919  1.00 45.80  ? 241 PHE B CD2 1 
ATOM 6311 C CE1 . PHE D 4 241 ? 127.984 120.904 89.311  1.00 45.80  ? 241 PHE B CE1 1 
ATOM 6312 C CE2 . PHE D 4 241 ? 127.479 122.373 91.125  1.00 45.80  ? 241 PHE B CE2 1 
ATOM 6313 C CZ  . PHE D 4 241 ? 127.279 121.976 89.820  1.00 45.80  ? 241 PHE B CZ  1 
ATOM 6314 N N   . ALA D 4 242 ? 128.425 119.311 94.977  1.00 42.73  ? 242 ALA B N   1 
ATOM 6315 C CA  . ALA D 4 242 ? 127.321 119.626 95.870  1.00 42.73  ? 242 ALA B CA  1 
ATOM 6316 C C   . ALA D 4 242 ? 127.322 121.112 96.200  1.00 42.73  ? 242 ALA B C   1 
ATOM 6317 O O   . ALA D 4 242 ? 128.383 121.716 96.389  1.00 42.73  ? 242 ALA B O   1 
ATOM 6318 C CB  . ALA D 4 242 ? 127.404 118.806 97.160  1.00 42.73  ? 242 ALA B CB  1 
ATOM 6319 N N   . THR D 4 243 ? 126.127 121.695 96.268  1.00 47.98  ? 243 THR B N   1 
ATOM 6320 C CA  . THR D 4 243 ? 125.959 123.112 96.550  1.00 47.98  ? 243 THR B CA  1 
ATOM 6321 C C   . THR D 4 243 ? 124.998 123.294 97.715  1.00 47.98  ? 243 THR B C   1 
ATOM 6322 O O   . THR D 4 243 ? 124.038 122.536 97.869  1.00 47.98  ? 243 THR B O   1 
ATOM 6323 C CB  . THR D 4 243 ? 125.425 123.876 95.329  1.00 47.98  ? 243 THR B CB  1 
ATOM 6324 O OG1 . THR D 4 243 ? 124.225 123.249 94.860  1.00 47.98  ? 243 THR B OG1 1 
ATOM 6325 C CG2 . THR D 4 243 ? 126.452 123.884 94.213  1.00 47.98  ? 243 THR B CG2 1 
ATOM 6326 N N   . GLY D 4 244 ? 125.265 124.308 98.532  1.00 45.98  ? 244 GLY B N   1 
ATOM 6327 C CA  . GLY D 4 244 ? 124.375 124.661 99.621  1.00 45.98  ? 244 GLY B CA  1 
ATOM 6328 C C   . GLY D 4 244 ? 123.813 126.056 99.449  1.00 45.98  ? 244 GLY B C   1 
ATOM 6329 O O   . GLY D 4 244 ? 124.514 126.948 98.961  1.00 45.98  ? 244 GLY B O   1 
ATOM 6330 N N   . SER D 4 245 ? 122.557 126.266 99.834  1.00 52.56  ? 245 SER B N   1 
ATOM 6331 C CA  . SER D 4 245 ? 121.891 127.542 99.625  1.00 52.56  ? 245 SER B CA  1 
ATOM 6332 C C   . SER D 4 245 ? 121.473 128.151 100.960 1.00 52.56  ? 245 SER B C   1 
ATOM 6333 O O   . SER D 4 245 ? 121.739 127.609 102.036 1.00 52.56  ? 245 SER B O   1 
ATOM 6334 C CB  . SER D 4 245 ? 120.685 127.373 98.701  1.00 52.56  ? 245 SER B CB  1 
ATOM 6335 O OG  . SER D 4 245 ? 120.289 128.615 98.145  1.00 52.56  ? 245 SER B OG  1 
ATOM 6336 N N   . ASP D 4 246 ? 120.806 129.301 100.873 1.00 56.86  ? 246 ASP B N   1 
ATOM 6337 C CA  . ASP D 4 246 ? 120.301 130.000 102.047 1.00 56.86  ? 246 ASP B CA  1 
ATOM 6338 C C   . ASP D 4 246 ? 118.917 129.528 102.470 1.00 56.86  ? 246 ASP B C   1 
ATOM 6339 O O   . ASP D 4 246 ? 118.423 129.972 103.512 1.00 56.86  ? 246 ASP B O   1 
ATOM 6340 C CB  . ASP D 4 246 ? 120.273 131.509 101.788 1.00 56.86  ? 246 ASP B CB  1 
ATOM 6341 C CG  . ASP D 4 246 ? 121.532 132.205 102.263 1.00 56.86  ? 246 ASP B CG  1 
ATOM 6342 O OD1 . ASP D 4 246 ? 122.111 131.761 103.277 1.00 56.86  ? 246 ASP B OD1 1 
ATOM 6343 O OD2 . ASP D 4 246 ? 121.943 133.197 101.625 1.00 56.86  ? 246 ASP B OD2 1 
ATOM 6344 N N   . ASP D 4 247 ? 118.282 128.645 101.696 1.00 60.80  ? 247 ASP B N   1 
ATOM 6345 C CA  . ASP D 4 247 ? 116.963 128.122 102.029 1.00 60.80  ? 247 ASP B CA  1 
ATOM 6346 C C   . ASP D 4 247 ? 117.055 126.741 102.681 1.00 60.80  ? 247 ASP B C   1 
ATOM 6347 O O   . ASP D 4 247 ? 116.204 125.874 102.439 1.00 60.80  ? 247 ASP B O   1 
ATOM 6348 C CB  . ASP D 4 247 ? 116.092 128.092 100.767 1.00 60.80  ? 247 ASP B CB  1 
ATOM 6349 C CG  . ASP D 4 247 ? 114.623 127.777 101.049 1.00 60.80  ? 247 ASP B CG  1 
ATOM 6350 O OD1 . ASP D 4 247 ? 114.248 127.550 102.219 1.00 60.80  ? 247 ASP B OD1 1 
ATOM 6351 O OD2 . ASP D 4 247 ? 113.834 127.757 100.081 1.00 60.80  ? 247 ASP B OD2 1 
ATOM 6352 N N   . ALA D 4 248 ? 118.102 126.506 103.476 1.00 59.59  ? 248 ALA B N   1 
ATOM 6353 C CA  . ALA D 4 248 ? 118.290 125.249 104.203 1.00 59.59  ? 248 ALA B CA  1 
ATOM 6354 C C   . ALA D 4 248 ? 118.255 124.043 103.267 1.00 59.59  ? 248 ALA B C   1 
ATOM 6355 O O   . ALA D 4 248 ? 117.698 122.995 103.599 1.00 59.59  ? 248 ALA B O   1 
ATOM 6356 C CB  . ALA D 4 248 ? 117.253 125.096 105.318 1.00 59.59  ? 248 ALA B CB  1 
ATOM 6357 N N   . THR D 4 249 ? 118.852 124.187 102.087 1.00 55.69  ? 249 THR B N   1 
ATOM 6358 C CA  . THR D 4 249 ? 118.798 123.134 101.085 1.00 55.69  ? 249 THR B CA  1 
ATOM 6359 C C   . THR D 4 249 ? 120.157 122.937 100.430 1.00 55.69  ? 249 THR B C   1 
ATOM 6360 O O   . THR D 4 249 ? 120.854 123.903 100.101 1.00 55.69  ? 249 THR B O   1 
ATOM 6361 C CB  . THR D 4 249 ? 117.738 123.436 100.013 1.00 55.69  ? 249 THR B CB  1 
ATOM 6362 O OG1 . THR D 4 249 ? 117.792 122.438 98.986  1.00 55.69  ? 249 THR B OG1 1 
ATOM 6363 C CG2 . THR D 4 249 ? 117.955 124.815 99.401  1.00 55.69  ? 249 THR B CG2 1 
ATOM 6364 N N   . CYS D 4 250 ? 120.518 121.672 100.234 1.00 55.18  ? 250 CYS B N   1 
ATOM 6365 C CA  . CYS D 4 250 ? 121.694 121.292 99.468  1.00 55.18  ? 250 CYS B CA  1 
ATOM 6366 C C   . CYS D 4 250 ? 121.250 120.500 98.246  1.00 55.18  ? 250 CYS B C   1 
ATOM 6367 O O   . CYS D 4 250 ? 120.223 119.824 98.270  1.00 55.18  ? 250 CYS B O   1 
ATOM 6368 C CB  . CYS D 4 250 ? 122.670 120.460 100.308 1.00 55.18  ? 250 CYS B CB  1 
ATOM 6369 S SG  . CYS D 4 250 ? 123.447 121.359 101.670 1.00 55.18  ? 250 CYS B SG  1 
ATOM 6370 N N   . ARG D 4 251 ? 122.018 120.604 97.168  1.00 55.54  ? 251 ARG B N   1 
ATOM 6371 C CA  . ARG D 4 251 ? 121.693 119.901 95.935  1.00 55.54  ? 251 ARG B CA  1 
ATOM 6372 C C   . ARG D 4 251 ? 122.954 119.299 95.338  1.00 55.54  ? 251 ARG B C   1 
ATOM 6373 O O   . ARG D 4 251 ? 124.016 119.928 95.350  1.00 55.54  ? 251 ARG B O   1 
ATOM 6374 C CB  . ARG D 4 251 ? 121.021 120.834 94.918  1.00 55.54  ? 251 ARG B CB  1 
ATOM 6375 C CG  . ARG D 4 251 ? 119.730 121.464 95.417  1.00 55.54  ? 251 ARG B CG  1 
ATOM 6376 C CD  . ARG D 4 251 ? 119.080 122.341 94.362  1.00 55.54  ? 251 ARG B CD  1 
ATOM 6377 N NE  . ARG D 4 251 ? 117.637 122.142 94.310  1.00 55.54  ? 251 ARG B NE  1 
ATOM 6378 C CZ  . ARG D 4 251 ? 116.756 122.873 94.979  1.00 55.54  ? 251 ARG B CZ  1 
ATOM 6379 N NH1 . ARG D 4 251 ? 117.137 123.865 95.767  1.00 55.54  ? 251 ARG B NH1 1 
ATOM 6380 N NH2 . ARG D 4 251 ? 115.460 122.602 94.854  1.00 55.54  ? 251 ARG B NH2 1 
ATOM 6381 N N   . LEU D 4 252 ? 122.833 118.084 94.808  1.00 55.40  ? 252 LEU B N   1 
ATOM 6382 C CA  . LEU D 4 252 ? 123.940 117.411 94.144  1.00 55.40  ? 252 LEU B CA  1 
ATOM 6383 C C   . LEU D 4 252 ? 123.716 117.443 92.639  1.00 55.40  ? 252 LEU B C   1 
ATOM 6384 O O   . LEU D 4 252 ? 122.634 117.086 92.162  1.00 55.40  ? 252 LEU B O   1 
ATOM 6385 C CB  . LEU D 4 252 ? 124.079 115.968 94.634  1.00 55.40  ? 252 LEU B CB  1 
ATOM 6386 C CG  . LEU D 4 252 ? 125.380 115.250 94.269  1.00 55.40  ? 252 LEU B CG  1 
ATOM 6387 C CD1 . LEU D 4 252 ? 126.523 115.743 95.139  1.00 55.40  ? 252 LEU B CD1 1 
ATOM 6388 C CD2 . LEU D 4 252 ? 125.214 113.747 94.406  1.00 55.40  ? 252 LEU B CD2 1 
ATOM 6389 N N   . PHE D 4 253 ? 124.732 117.879 91.898  1.00 55.23  ? 253 PHE B N   1 
ATOM 6390 C CA  . PHE D 4 253 ? 124.672 117.967 90.448  1.00 55.23  ? 253 PHE B CA  1 
ATOM 6391 C C   . PHE D 4 253 ? 125.773 117.111 89.839  1.00 55.23  ? 253 PHE B C   1 
ATOM 6392 O O   . PHE D 4 253 ? 126.871 116.996 90.392  1.00 55.23  ? 253 PHE B O   1 
ATOM 6393 C CB  . PHE D 4 253 ? 124.824 119.415 89.965  1.00 55.23  ? 253 PHE B CB  1 
ATOM 6394 C CG  . PHE D 4 253 ? 123.786 120.353 90.513  1.00 55.23  ? 253 PHE B CG  1 
ATOM 6395 C CD1 . PHE D 4 253 ? 122.564 120.501 89.880  1.00 55.23  ? 253 PHE B CD1 1 
ATOM 6396 C CD2 . PHE D 4 253 ? 124.037 121.093 91.656  1.00 55.23  ? 253 PHE B CD2 1 
ATOM 6397 C CE1 . PHE D 4 253 ? 121.609 121.365 90.379  1.00 55.23  ? 253 PHE B CE1 1 
ATOM 6398 C CE2 . PHE D 4 253 ? 123.086 121.959 92.160  1.00 55.23  ? 253 PHE B CE2 1 
ATOM 6399 C CZ  . PHE D 4 253 ? 121.871 122.094 91.521  1.00 55.23  ? 253 PHE B CZ  1 
ATOM 6400 N N   . ASP D 4 254 ? 125.467 116.508 88.695  1.00 66.50  ? 254 ASP B N   1 
ATOM 6401 C CA  . ASP D 4 254 ? 126.414 115.686 87.954  1.00 66.50  ? 254 ASP B CA  1 
ATOM 6402 C C   . ASP D 4 254 ? 126.788 116.398 86.662  1.00 66.50  ? 254 ASP B C   1 
ATOM 6403 O O   . ASP D 4 254 ? 125.908 116.820 85.904  1.00 66.50  ? 254 ASP B O   1 
ATOM 6404 C CB  . ASP D 4 254 ? 125.824 114.307 87.651  1.00 66.50  ? 254 ASP B CB  1 
ATOM 6405 C CG  . ASP D 4 254 ? 126.882 113.295 87.258  1.00 66.50  ? 254 ASP B CG  1 
ATOM 6406 O OD1 . ASP D 4 254 ? 127.367 113.355 86.109  1.00 66.50  ? 254 ASP B OD1 1 
ATOM 6407 O OD2 . ASP D 4 254 ? 127.231 112.440 88.099  1.00 66.50  ? 254 ASP B OD2 1 
ATOM 6408 N N   . LEU D 4 255 ? 128.094 116.537 86.421  1.00 66.61  ? 255 LEU B N   1 
ATOM 6409 C CA  . LEU D 4 255 ? 128.555 117.229 85.221  1.00 66.61  ? 255 LEU B CA  1 
ATOM 6410 C C   . LEU D 4 255 ? 128.136 116.488 83.957  1.00 66.61  ? 255 LEU B C   1 
ATOM 6411 O O   . LEU D 4 255 ? 127.683 117.108 82.987  1.00 66.61  ? 255 LEU B O   1 
ATOM 6412 C CB  . LEU D 4 255 ? 130.073 117.398 85.265  1.00 66.61  ? 255 LEU B CB  1 
ATOM 6413 C CG  . LEU D 4 255 ? 130.628 118.253 86.406  1.00 66.61  ? 255 LEU B CG  1 
ATOM 6414 C CD1 . LEU D 4 255 ? 132.149 118.239 86.397  1.00 66.61  ? 255 LEU B CD1 1 
ATOM 6415 C CD2 . LEU D 4 255 ? 130.100 119.675 86.317  1.00 66.61  ? 255 LEU B CD2 1 
ATOM 6416 N N   . ARG D 4 256 ? 128.284 115.161 83.947  1.00 79.85  ? 256 ARG B N   1 
ATOM 6417 C CA  . ARG D 4 256 ? 127.895 114.383 82.775  1.00 79.85  ? 256 ARG B CA  1 
ATOM 6418 C C   . ARG D 4 256 ? 126.389 114.436 82.547  1.00 79.85  ? 256 ARG B C   1 
ATOM 6419 O O   . ARG D 4 256 ? 125.933 114.587 81.408  1.00 79.85  ? 256 ARG B O   1 
ATOM 6420 C CB  . ARG D 4 256 ? 128.365 112.937 82.928  1.00 79.85  ? 256 ARG B CB  1 
ATOM 6421 N N   . ALA D 4 257 ? 125.601 114.314 83.618  1.00 81.73  ? 257 ALA B N   1 
ATOM 6422 C CA  . ALA D 4 257 ? 124.150 114.348 83.483  1.00 81.73  ? 257 ALA B CA  1 
ATOM 6423 C C   . ALA D 4 257 ? 123.625 115.760 83.261  1.00 81.73  ? 257 ALA B C   1 
ATOM 6424 O O   . ALA D 4 257 ? 122.560 115.930 82.655  1.00 81.73  ? 257 ALA B O   1 
ATOM 6425 C CB  . ALA D 4 257 ? 123.492 113.734 84.719  1.00 81.73  ? 257 ALA B CB  1 
ATOM 6426 N N   . ASP D 4 258 ? 124.345 116.773 83.746  1.00 79.84  ? 258 ASP B N   1 
ATOM 6427 C CA  . ASP D 4 258 ? 123.964 118.180 83.620  1.00 79.84  ? 258 ASP B CA  1 
ATOM 6428 C C   . ASP D 4 258 ? 122.611 118.474 84.261  1.00 79.84  ? 258 ASP B C   1 
ATOM 6429 O O   . ASP D 4 258 ? 121.941 119.442 83.887  1.00 79.84  ? 258 ASP B O   1 
ATOM 6430 C CB  . ASP D 4 258 ? 123.965 118.628 82.152  1.00 79.84  ? 258 ASP B CB  1 
ATOM 6431 C CG  . ASP D 4 258 ? 124.257 120.108 81.993  1.00 79.84  ? 258 ASP B CG  1 
ATOM 6432 O OD1 . ASP D 4 258 ? 124.385 120.806 83.020  1.00 79.84  ? 258 ASP B OD1 1 
ATOM 6433 O OD2 . ASP D 4 258 ? 124.360 120.574 80.838  1.00 79.84  ? 258 ASP B OD2 1 
ATOM 6434 N N   . GLN D 4 259 ? 122.197 117.658 85.228  1.00 80.74  ? 259 GLN B N   1 
ATOM 6435 C CA  . GLN D 4 259 ? 120.898 117.798 85.867  1.00 80.74  ? 259 GLN B CA  1 
ATOM 6436 C C   . GLN D 4 259 ? 121.050 117.553 87.362  1.00 80.74  ? 259 GLN B C   1 
ATOM 6437 O O   . GLN D 4 259 ? 121.951 116.831 87.797  1.00 80.74  ? 259 GLN B O   1 
ATOM 6438 C CB  . GLN D 4 259 ? 119.876 116.822 85.254  1.00 80.74  ? 259 GLN B CB  1 
ATOM 6439 C CG  . GLN D 4 259 ? 118.525 116.763 85.953  1.00 80.74  ? 259 GLN B CG  1 
ATOM 6440 C CD  . GLN D 4 259 ? 117.522 115.901 85.214  1.00 80.74  ? 259 GLN B CD  1 
ATOM 6441 O OE1 . GLN D 4 259 ? 117.758 115.487 84.080  1.00 80.74  ? 259 GLN B OE1 1 
ATOM 6442 N NE2 . GLN D 4 259 ? 116.393 115.625 85.856  1.00 80.74  ? 259 GLN B NE2 1 
ATOM 6443 N N   . GLU D 4 260 ? 120.170 118.177 88.145  1.00 69.23  ? 260 GLU B N   1 
ATOM 6444 C CA  . GLU D 4 260 ? 120.144 117.947 89.583  1.00 69.23  ? 260 GLU B CA  1 
ATOM 6445 C C   . GLU D 4 260 ? 119.938 116.468 89.885  1.00 69.23  ? 260 GLU B C   1 
ATOM 6446 O O   . GLU D 4 260 ? 119.068 115.813 89.305  1.00 69.23  ? 260 GLU B O   1 
ATOM 6447 C CB  . GLU D 4 260 ? 119.032 118.774 90.230  1.00 69.23  ? 260 GLU B CB  1 
ATOM 6448 C CG  . GLU D 4 260 ? 118.738 118.399 91.672  1.00 69.23  ? 260 GLU B CG  1 
ATOM 6449 C CD  . GLU D 4 260 ? 118.125 119.539 92.457  1.00 69.23  ? 260 GLU B CD  1 
ATOM 6450 O OE1 . GLU D 4 260 ? 117.831 120.591 91.851  1.00 69.23  ? 260 GLU B OE1 1 
ATOM 6451 O OE2 . GLU D 4 260 ? 117.931 119.380 93.681  1.00 69.23  ? 260 GLU B OE2 1 
ATOM 6452 N N   . LEU D 4 261 ? 120.747 115.941 90.804  1.00 68.81  ? 261 LEU B N   1 
ATOM 6453 C CA  . LEU D 4 261 ? 120.704 114.525 91.152  1.00 68.81  ? 261 LEU B CA  1 
ATOM 6454 C C   . LEU D 4 261 ? 119.798 114.258 92.349  1.00 68.81  ? 261 LEU B C   1 
ATOM 6455 O O   . LEU D 4 261 ? 118.824 113.509 92.236  1.00 68.81  ? 261 LEU B O   1 
ATOM 6456 C CB  . LEU D 4 261 ? 122.123 114.007 91.424  1.00 68.81  ? 261 LEU B CB  1 
ATOM 6457 C CG  . LEU D 4 261 ? 122.369 112.546 91.049  1.00 68.81  ? 261 LEU B CG  1 
ATOM 6458 C CD1 . LEU D 4 261 ? 122.201 112.353 89.553  1.00 68.81  ? 261 LEU B CD1 1 
ATOM 6459 C CD2 . LEU D 4 261 ? 123.749 112.100 91.493  1.00 68.81  ? 261 LEU B CD2 1 
ATOM 6460 N N   . MET D 4 262 ? 120.097 114.863 93.498  1.00 66.74  ? 262 MET B N   1 
ATOM 6461 C CA  . MET D 4 262 ? 119.304 114.627 94.695  1.00 66.74  ? 262 MET B CA  1 
ATOM 6462 C C   . MET D 4 262 ? 119.501 115.781 95.671  1.00 66.74  ? 262 MET B C   1 
ATOM 6463 O O   . MET D 4 262 ? 120.557 116.425 95.699  1.00 66.74  ? 262 MET B O   1 
ATOM 6464 C CB  . MET D 4 262 ? 119.655 113.262 95.312  1.00 66.74  ? 262 MET B CB  1 
ATOM 6465 C CG  . MET D 4 262 ? 118.854 112.868 96.544  1.00 66.74  ? 262 MET B CG  1 
ATOM 6466 S SD  . MET D 4 262 ? 119.311 111.234 97.165  1.00 66.74  ? 262 MET B SD  1 
ATOM 6467 C CE  . MET D 4 262 ? 120.930 111.531 97.861  1.00 66.74  ? 262 MET B CE  1 
ATOM 6468 N N   . THR D 4 263 ? 118.459 116.039 96.461  1.00 60.61  ? 263 THR B N   1 
ATOM 6469 C CA  . THR D 4 263 ? 118.353 117.228 97.296  1.00 60.61  ? 263 THR B CA  1 
ATOM 6470 C C   . THR D 4 263 ? 118.316 116.847 98.771  1.00 60.61  ? 263 THR B C   1 
ATOM 6471 O O   . THR D 4 263 ? 117.674 115.865 99.156  1.00 60.61  ? 263 THR B O   1 
ATOM 6472 C CB  . THR D 4 263 ? 117.097 118.030 96.934  1.00 60.61  ? 263 THR B CB  1 
ATOM 6473 O OG1 . THR D 4 263 ? 117.087 118.296 95.526  1.00 60.61  ? 263 THR B OG1 1 
ATOM 6474 C CG2 . THR D 4 263 ? 117.058 119.351 97.689  1.00 60.61  ? 263 THR B CG2 1 
ATOM 6475 N N   . TYR D 4 264 ? 119.010 117.636 99.588  1.00 58.62  ? 264 TYR B N   1 
ATOM 6476 C CA  . TYR D 4 264 ? 119.097 117.439 101.029 1.00 58.62  ? 264 TYR B CA  1 
ATOM 6477 C C   . TYR D 4 264 ? 118.355 118.583 101.708 1.00 58.62  ? 264 TYR B C   1 
ATOM 6478 O O   . TYR D 4 264 ? 118.697 119.754 101.502 1.00 58.62  ? 264 TYR B O   1 
ATOM 6479 C CB  . TYR D 4 264 ? 120.556 117.419 101.485 1.00 58.62  ? 264 TYR B CB  1 
ATOM 6480 C CG  . TYR D 4 264 ? 121.413 116.389 100.789 1.00 58.62  ? 264 TYR B CG  1 
ATOM 6481 C CD1 . TYR D 4 264 ? 120.845 115.285 100.172 1.00 58.62  ? 264 TYR B CD1 1 
ATOM 6482 C CD2 . TYR D 4 264 ? 122.789 116.545 100.712 1.00 58.62  ? 264 TYR B CD2 1 
ATOM 6483 C CE1 . TYR D 4 264 ? 121.621 114.359 99.524  1.00 58.62  ? 264 TYR B CE1 1 
ATOM 6484 C CE2 . TYR D 4 264 ? 123.575 115.618 100.062 1.00 58.62  ? 264 TYR B CE2 1 
ATOM 6485 C CZ  . TYR D 4 264 ? 122.984 114.527 99.469  1.00 58.62  ? 264 TYR B CZ  1 
ATOM 6486 O OH  . TYR D 4 264 ? 123.755 113.597 98.816  1.00 58.62  ? 264 TYR B OH  1 
ATOM 6487 N N   . SER D 4 265 ? 117.350 118.246 102.512 1.00 65.72  ? 265 SER B N   1 
ATOM 6488 C CA  . SER D 4 265 ? 116.573 119.252 103.221 1.00 65.72  ? 265 SER B CA  1 
ATOM 6489 C C   . SER D 4 265 ? 115.962 118.628 104.467 1.00 65.72  ? 265 SER B C   1 
ATOM 6490 O O   . SER D 4 265 ? 115.817 117.407 104.568 1.00 65.72  ? 265 SER B O   1 
ATOM 6491 C CB  . SER D 4 265 ? 115.477 119.852 102.331 1.00 65.72  ? 265 SER B CB  1 
ATOM 6492 O OG  . SER D 4 265 ? 116.033 120.531 101.219 1.00 65.72  ? 265 SER B OG  1 
ATOM 6493 N N   . HIS D 4 266 ? 115.605 119.488 105.418 1.00 70.27  ? 266 HIS B N   1 
ATOM 6494 C CA  . HIS D 4 266 ? 114.972 119.064 106.658 1.00 70.27  ? 266 HIS B CA  1 
ATOM 6495 C C   . HIS D 4 266 ? 113.943 120.103 107.074 1.00 70.27  ? 266 HIS B C   1 
ATOM 6496 O O   . HIS D 4 266 ? 114.171 121.307 106.925 1.00 70.27  ? 266 HIS B O   1 
ATOM 6497 C CB  . HIS D 4 266 ? 116.003 118.866 107.777 1.00 70.27  ? 266 HIS B CB  1 
ATOM 6498 C CG  . HIS D 4 266 ? 115.640 117.787 108.749 1.00 70.27  ? 266 HIS B CG  1 
ATOM 6499 N ND1 . HIS D 4 266 ? 114.593 117.906 109.637 1.00 70.27  ? 266 HIS B ND1 1 
ATOM 6500 C CD2 . HIS D 4 266 ? 116.185 116.567 108.972 1.00 70.27  ? 266 HIS B CD2 1 
ATOM 6501 C CE1 . HIS D 4 266 ? 114.508 116.807 110.365 1.00 70.27  ? 266 HIS B CE1 1 
ATOM 6502 N NE2 . HIS D 4 266 ? 115.463 115.979 109.981 1.00 70.27  ? 266 HIS B NE2 1 
ATOM 6503 N N   . ASP D 4 267 ? 112.807 119.629 107.591 1.00 69.86  ? 267 ASP B N   1 
ATOM 6504 C CA  . ASP D 4 267 ? 111.759 120.545 108.033 1.00 69.86  ? 267 ASP B CA  1 
ATOM 6505 C C   . ASP D 4 267 ? 112.205 121.363 109.238 1.00 69.86  ? 267 ASP B C   1 
ATOM 6506 O O   . ASP D 4 267 ? 111.898 122.558 109.332 1.00 69.86  ? 267 ASP B O   1 
ATOM 6507 C CB  . ASP D 4 267 ? 110.481 119.766 108.348 1.00 69.86  ? 267 ASP B CB  1 
ATOM 6508 C CG  . ASP D 4 267 ? 110.706 118.652 109.355 1.00 69.86  ? 267 ASP B CG  1 
ATOM 6509 O OD1 . ASP D 4 267 ? 111.870 118.419 109.742 1.00 69.86  ? 267 ASP B OD1 1 
ATOM 6510 O OD2 . ASP D 4 267 ? 109.715 118.008 109.759 1.00 69.86  ? 267 ASP B OD2 1 
ATOM 6511 N N   . ASN D 4 268 ? 112.924 120.738 110.173 1.00 68.97  ? 268 ASN B N   1 
ATOM 6512 C CA  . ASN D 4 268 ? 113.391 121.456 111.355 1.00 68.97  ? 268 ASN B CA  1 
ATOM 6513 C C   . ASN D 4 268 ? 114.389 122.545 110.984 1.00 68.97  ? 268 ASN B C   1 
ATOM 6514 O O   . ASN D 4 268 ? 114.359 123.645 111.548 1.00 68.97  ? 268 ASN B O   1 
ATOM 6515 C CB  . ASN D 4 268 ? 114.012 120.477 112.353 1.00 68.97  ? 268 ASN B CB  1 
ATOM 6516 C CG  . ASN D 4 268 ? 112.969 119.717 113.148 1.00 68.97  ? 268 ASN B CG  1 
ATOM 6517 O OD1 . ASN D 4 268 ? 111.970 120.285 113.588 1.00 68.97  ? 268 ASN B OD1 1 
ATOM 6518 N ND2 . ASN D 4 268 ? 113.198 118.422 113.337 1.00 68.97  ? 268 ASN B ND2 1 
ATOM 6519 N N   . ILE D 4 269 ? 115.281 122.259 110.042 1.00 63.86  ? 269 ILE B N   1 
ATOM 6520 C CA  . ILE D 4 269 ? 116.313 123.210 109.647 1.00 63.86  ? 269 ILE B CA  1 
ATOM 6521 C C   . ILE D 4 269 ? 115.703 124.260 108.728 1.00 63.86  ? 269 ILE B C   1 
ATOM 6522 O O   . ILE D 4 269 ? 115.034 123.928 107.742 1.00 63.86  ? 269 ILE B O   1 
ATOM 6523 C CB  . ILE D 4 269 ? 117.484 122.488 108.964 1.00 63.86  ? 269 ILE B CB  1 
ATOM 6524 C CG1 . ILE D 4 269 ? 118.118 121.476 109.921 1.00 63.86  ? 269 ILE B CG1 1 
ATOM 6525 C CG2 . ILE D 4 269 ? 118.517 123.491 108.493 1.00 63.86  ? 269 ILE B CG2 1 
ATOM 6526 C CD1 . ILE D 4 269 ? 119.098 120.537 109.254 1.00 63.86  ? 269 ILE B CD1 1 
ATOM 6527 N N   . ILE D 4 270 ? 115.933 125.532 109.049 1.00 63.60  ? 270 ILE B N   1 
ATOM 6528 C CA  . ILE D 4 270 ? 115.410 126.637 108.253 1.00 63.60  ? 270 ILE B CA  1 
ATOM 6529 C C   . ILE D 4 270 ? 116.572 127.514 107.803 1.00 63.60  ? 270 ILE B C   1 
ATOM 6530 O O   . ILE D 4 270 ? 116.507 128.169 106.755 1.00 63.60  ? 270 ILE B O   1 
ATOM 6531 C CB  . ILE D 4 270 ? 114.369 127.444 109.053 1.00 63.60  ? 270 ILE B CB  1 
ATOM 6532 C CG1 . ILE D 4 270 ? 113.188 126.552 109.441 1.00 63.60  ? 270 ILE B CG1 1 
ATOM 6533 C CG2 . ILE D 4 270 ? 113.874 128.646 108.258 1.00 63.60  ? 270 ILE B CG2 1 
ATOM 6534 C CD1 . ILE D 4 270 ? 112.242 126.252 108.298 1.00 63.60  ? 270 ILE B CD1 1 
ATOM 6535 N N   . CYS D 4 271 ? 117.655 127.508 108.574 1.00 57.70  ? 271 CYS B N   1 
ATOM 6536 C CA  . CYS D 4 271 ? 118.811 128.339 108.274 1.00 57.70  ? 271 CYS B CA  1 
ATOM 6537 C C   . CYS D 4 271 ? 119.605 127.769 107.104 1.00 57.70  ? 271 CYS B C   1 
ATOM 6538 O O   . CYS D 4 271 ? 119.625 126.559 106.866 1.00 57.70  ? 271 CYS B O   1 
ATOM 6539 C CB  . CYS D 4 271 ? 119.713 128.460 109.500 1.00 57.70  ? 271 CYS B CB  1 
ATOM 6540 S SG  . CYS D 4 271 ? 120.546 126.925 109.949 1.00 57.70  ? 271 CYS B SG  1 
ATOM 6541 N N   . GLY D 4 272 ? 120.278 128.661 106.379 1.00 51.78  ? 272 GLY B N   1 
ATOM 6542 C CA  . GLY D 4 272 ? 121.020 128.281 105.198 1.00 51.78  ? 272 GLY B CA  1 
ATOM 6543 C C   . GLY D 4 272 ? 122.354 127.627 105.510 1.00 51.78  ? 272 GLY B C   1 
ATOM 6544 O O   . GLY D 4 272 ? 122.751 127.448 106.661 1.00 51.78  ? 272 GLY B O   1 
ATOM 6545 N N   . ILE D 4 273 ? 123.057 127.264 104.439 1.00 44.08  ? 273 ILE B N   1 
ATOM 6546 C CA  . ILE D 4 273 ? 124.350 126.593 104.522 1.00 44.08  ? 273 ILE B CA  1 
ATOM 6547 C C   . ILE D 4 273 ? 125.445 127.618 104.272 1.00 44.08  ? 273 ILE B C   1 
ATOM 6548 O O   . ILE D 4 273 ? 125.366 128.403 103.319 1.00 44.08  ? 273 ILE B O   1 
ATOM 6549 C CB  . ILE D 4 273 ? 124.447 125.433 103.514 1.00 44.08  ? 273 ILE B CB  1 
ATOM 6550 C CG1 . ILE D 4 273 ? 123.416 124.346 103.824 1.00 44.08  ? 273 ILE B CG1 1 
ATOM 6551 C CG2 . ILE D 4 273 ? 125.849 124.843 103.508 1.00 44.08  ? 273 ILE B CG2 1 
ATOM 6552 C CD1 . ILE D 4 273 ? 122.086 124.523 103.119 1.00 44.08  ? 273 ILE B CD1 1 
ATOM 6553 N N   . THR D 4 274 ? 126.466 127.617 105.128 1.00 38.68  ? 274 THR B N   1 
ATOM 6554 C CA  . THR D 4 274 ? 127.602 128.518 104.978 1.00 38.68  ? 274 THR B CA  1 
ATOM 6555 C C   . THR D 4 274 ? 128.819 127.853 104.352 1.00 38.68  ? 274 THR B C   1 
ATOM 6556 O O   . THR D 4 274 ? 129.597 128.530 103.673 1.00 38.68  ? 274 THR B O   1 
ATOM 6557 C CB  . THR D 4 274 ? 128.000 129.103 106.338 1.00 38.68  ? 274 THR B CB  1 
ATOM 6558 O OG1 . THR D 4 274 ? 128.599 128.080 107.143 1.00 38.68  ? 274 THR B OG1 1 
ATOM 6559 C CG2 . THR D 4 274 ? 126.780 129.657 107.057 1.00 38.68  ? 274 THR B CG2 1 
ATOM 6560 N N   . SER D 4 275 ? 129.002 126.551 104.562 1.00 36.69  ? 275 SER B N   1 
ATOM 6561 C CA  . SER D 4 275 ? 130.134 125.832 103.996 1.00 36.69  ? 275 SER B CA  1 
ATOM 6562 C C   . SER D 4 275 ? 129.759 124.368 103.830 1.00 36.69  ? 275 SER B C   1 
ATOM 6563 O O   . SER D 4 275 ? 128.895 123.849 104.543 1.00 36.69  ? 275 SER B O   1 
ATOM 6564 C CB  . SER D 4 275 ? 131.383 125.966 104.874 1.00 36.69  ? 275 SER B CB  1 
ATOM 6565 O OG  . SER D 4 275 ? 132.457 125.202 104.354 1.00 36.69  ? 275 SER B OG  1 
ATOM 6566 N N   . VAL D 4 276 ? 130.419 123.704 102.881 1.00 34.97  ? 276 VAL B N   1 
ATOM 6567 C CA  . VAL D 4 276 ? 130.170 122.294 102.610 1.00 34.97  ? 276 VAL B CA  1 
ATOM 6568 C C   . VAL D 4 276 ? 131.437 121.685 102.026 1.00 34.97  ? 276 VAL B C   1 
ATOM 6569 O O   . VAL D 4 276 ? 132.222 122.363 101.357 1.00 34.97  ? 276 VAL B O   1 
ATOM 6570 C CB  . VAL D 4 276 ? 128.957 122.103 101.666 1.00 34.97  ? 276 VAL B CB  1 
ATOM 6571 C CG1 . VAL D 4 276 ? 129.292 122.545 100.248 1.00 34.97  ? 276 VAL B CG1 1 
ATOM 6572 C CG2 . VAL D 4 276 ? 128.469 120.667 101.695 1.00 34.97  ? 276 VAL B CG2 1 
ATOM 6573 N N   . SER D 4 277 ? 131.644 120.399 102.300 1.00 36.47  ? 277 SER B N   1 
ATOM 6574 C CA  . SER D 4 277 ? 132.798 119.680 101.777 1.00 36.47  ? 277 SER B CA  1 
ATOM 6575 C C   . SER D 4 277 ? 132.481 118.193 101.751 1.00 36.47  ? 277 SER B C   1 
ATOM 6576 O O   . SER D 4 277 ? 131.550 117.725 102.410 1.00 36.47  ? 277 SER B O   1 
ATOM 6577 C CB  . SER D 4 277 ? 134.057 119.949 102.609 1.00 36.47  ? 277 SER B CB  1 
ATOM 6578 O OG  . SER D 4 277 ? 135.205 119.393 101.992 1.00 36.47  ? 277 SER B OG  1 
ATOM 6579 N N   . PHE D 4 278 ? 133.277 117.457 100.982 1.00 41.31  ? 278 PHE B N   1 
ATOM 6580 C CA  . PHE D 4 278 ? 133.112 116.023 100.810 1.00 41.31  ? 278 PHE B CA  1 
ATOM 6581 C C   . PHE D 4 278 ? 134.211 115.269 101.547 1.00 41.31  ? 278 PHE B C   1 
ATOM 6582 O O   . PHE D 4 278 ? 135.273 115.815 101.857 1.00 41.31  ? 278 PHE B O   1 
ATOM 6583 C CB  . PHE D 4 278 ? 133.132 115.641 99.325  1.00 41.31  ? 278 PHE B CB  1 
ATOM 6584 C CG  . PHE D 4 278 ? 131.774 115.601 98.687  1.00 41.31  ? 278 PHE B CG  1 
ATOM 6585 C CD1 . PHE D 4 278 ? 130.884 114.584 98.986  1.00 41.31  ? 278 PHE B CD1 1 
ATOM 6586 C CD2 . PHE D 4 278 ? 131.392 116.574 97.780  1.00 41.31  ? 278 PHE B CD2 1 
ATOM 6587 C CE1 . PHE D 4 278 ? 129.635 114.542 98.397  1.00 41.31  ? 278 PHE B CE1 1 
ATOM 6588 C CE2 . PHE D 4 278 ? 130.146 116.537 97.187  1.00 41.31  ? 278 PHE B CE2 1 
ATOM 6589 C CZ  . PHE D 4 278 ? 129.266 115.520 97.495  1.00 41.31  ? 278 PHE B CZ  1 
ATOM 6590 N N   . SER D 4 279 ? 133.940 113.996 101.824 1.00 44.66  ? 279 SER B N   1 
ATOM 6591 C CA  . SER D 4 279 ? 134.919 113.126 102.455 1.00 44.66  ? 279 SER B CA  1 
ATOM 6592 C C   . SER D 4 279 ? 135.876 112.568 101.403 1.00 44.66  ? 279 SER B C   1 
ATOM 6593 O O   . SER D 4 279 ? 135.806 112.905 100.217 1.00 44.66  ? 279 SER B O   1 
ATOM 6594 C CB  . SER D 4 279 ? 134.217 112.005 103.218 1.00 44.66  ? 279 SER B CB  1 
ATOM 6595 O OG  . SER D 4 279 ? 135.157 111.143 103.835 1.00 44.66  ? 279 SER B OG  1 
ATOM 6596 N N   . LYS D 4 280 ? 136.794 111.705 101.845 1.00 46.68  ? 280 LYS B N   1 
ATOM 6597 C CA  . LYS D 4 280 ? 137.751 111.110 100.916 1.00 46.68  ? 280 LYS B CA  1 
ATOM 6598 C C   . LYS D 4 280 ? 137.052 110.226 99.892  1.00 46.68  ? 280 LYS B C   1 
ATOM 6599 O O   . LYS D 4 280 ? 137.368 110.277 98.697  1.00 46.68  ? 280 LYS B O   1 
ATOM 6600 C CB  . LYS D 4 280 ? 138.803 110.310 101.684 1.00 46.68  ? 280 LYS B CB  1 
ATOM 6601 C CG  . LYS D 4 280 ? 139.894 109.725 100.801 1.00 46.68  ? 280 LYS B CG  1 
ATOM 6602 C CD  . LYS D 4 280 ? 140.937 108.988 101.622 1.00 46.68  ? 280 LYS B CD  1 
ATOM 6603 C CE  . LYS D 4 280 ? 142.074 108.484 100.749 1.00 46.68  ? 280 LYS B CE  1 
ATOM 6604 N NZ  . LYS D 4 280 ? 141.626 107.413 99.817  1.00 46.68  ? 280 LYS B NZ  1 
ATOM 6605 N N   . SER D 4 281 ? 136.100 109.409 100.337 1.00 49.88  ? 281 SER B N   1 
ATOM 6606 C CA  . SER D 4 281 ? 135.348 108.542 99.442  1.00 49.88  ? 281 SER B CA  1 
ATOM 6607 C C   . SER D 4 281 ? 134.097 109.203 98.882  1.00 49.88  ? 281 SER B C   1 
ATOM 6608 O O   . SER D 4 281 ? 133.463 108.635 97.986  1.00 49.88  ? 281 SER B O   1 
ATOM 6609 C CB  . SER D 4 281 ? 134.955 107.249 100.164 1.00 49.88  ? 281 SER B CB  1 
ATOM 6610 O OG  . SER D 4 281 ? 133.893 107.474 101.074 1.00 49.88  ? 281 SER B OG  1 
ATOM 6611 N N   . GLY D 4 282 ? 133.727 110.380 99.382  1.00 51.15  ? 282 GLY B N   1 
ATOM 6612 C CA  . GLY D 4 282 ? 132.535 111.062 98.931  1.00 51.15  ? 282 GLY B CA  1 
ATOM 6613 C C   . GLY D 4 282 ? 131.242 110.563 99.533  1.00 51.15  ? 282 GLY B C   1 
ATOM 6614 O O   . GLY D 4 282 ? 130.176 111.082 99.181  1.00 51.15  ? 282 GLY B O   1 
ATOM 6615 N N   . ARG D 4 283 ? 131.297 109.571 100.425 1.00 55.10  ? 283 ARG B N   1 
ATOM 6616 C CA  . ARG D 4 283 ? 130.076 109.053 101.035 1.00 55.10  ? 283 ARG B CA  1 
ATOM 6617 C C   . ARG D 4 283 ? 129.486 110.050 102.025 1.00 55.10  ? 283 ARG B C   1 
ATOM 6618 O O   . ARG D 4 283 ? 128.260 110.169 102.140 1.00 55.10  ? 283 ARG B O   1 
ATOM 6619 C CB  . ARG D 4 283 ? 130.365 107.716 101.720 1.00 55.10  ? 283 ARG B CB  1 
ATOM 6620 C CG  . ARG D 4 283 ? 129.245 107.209 102.613 1.00 55.10  ? 283 ARG B CG  1 
ATOM 6621 C CD  . ARG D 4 283 ? 128.321 106.270 101.859 1.00 55.10  ? 283 ARG B CD  1 
ATOM 6622 N NE  . ARG D 4 283 ? 127.032 106.122 102.524 1.00 55.10  ? 283 ARG B NE  1 
ATOM 6623 C CZ  . ARG D 4 283 ? 126.103 105.245 102.170 1.00 55.10  ? 283 ARG B CZ  1 
ATOM 6624 N NH1 . ARG D 4 283 ? 126.287 104.415 101.156 1.00 55.10  ? 283 ARG B NH1 1 
ATOM 6625 N NH2 . ARG D 4 283 ? 124.962 105.198 102.850 1.00 55.10  ? 283 ARG B NH2 1 
ATOM 6626 N N   . LEU D 4 284 ? 130.337 110.778 102.739 1.00 47.31  ? 284 LEU B N   1 
ATOM 6627 C CA  . LEU D 4 284 ? 129.905 111.732 103.751 1.00 47.31  ? 284 LEU B CA  1 
ATOM 6628 C C   . LEU D 4 284 ? 130.011 113.147 103.203 1.00 47.31  ? 284 LEU B C   1 
ATOM 6629 O O   . LEU D 4 284 ? 131.032 113.513 102.611 1.00 47.31  ? 284 LEU B O   1 
ATOM 6630 C CB  . LEU D 4 284 ? 130.750 111.600 105.019 1.00 47.31  ? 284 LEU B CB  1 
ATOM 6631 C CG  . LEU D 4 284 ? 130.593 110.326 105.849 1.00 47.31  ? 284 LEU B CG  1 
ATOM 6632 C CD1 . LEU D 4 284 ? 131.267 110.499 107.199 1.00 47.31  ? 284 LEU B CD1 1 
ATOM 6633 C CD2 . LEU D 4 284 ? 129.125 109.967 106.018 1.00 47.31  ? 284 LEU B CD2 1 
ATOM 6634 N N   . LEU D 4 285 ? 128.958 113.939 103.399 1.00 41.74  ? 285 LEU B N   1 
ATOM 6635 C CA  . LEU D 4 285 ? 128.951 115.350 103.029 1.00 41.74  ? 285 LEU B CA  1 
ATOM 6636 C C   . LEU D 4 285 ? 128.763 116.167 104.300 1.00 41.74  ? 285 LEU B C   1 
ATOM 6637 O O   . LEU D 4 285 ? 127.679 116.162 104.889 1.00 41.74  ? 285 LEU B O   1 
ATOM 6638 C CB  . LEU D 4 285 ? 127.848 115.648 102.015 1.00 41.74  ? 285 LEU B CB  1 
ATOM 6639 C CG  . LEU D 4 285 ? 127.812 117.085 101.494 1.00 41.74  ? 285 LEU B CG  1 
ATOM 6640 C CD1 . LEU D 4 285 ? 128.940 117.318 100.504 1.00 41.74  ? 285 LEU B CD1 1 
ATOM 6641 C CD2 . LEU D 4 285 ? 126.468 117.405 100.864 1.00 41.74  ? 285 LEU B CD2 1 
ATOM 6642 N N   . LEU D 4 286 ? 129.814 116.856 104.729 1.00 39.43  ? 286 LEU B N   1 
ATOM 6643 C CA  . LEU D 4 286 ? 129.764 117.658 105.945 1.00 39.43  ? 286 LEU B CA  1 
ATOM 6644 C C   . LEU D 4 286 ? 129.381 119.087 105.581 1.00 39.43  ? 286 LEU B C   1 
ATOM 6645 O O   . LEU D 4 286 ? 130.094 119.751 104.821 1.00 39.43  ? 286 LEU B O   1 
ATOM 6646 C CB  . LEU D 4 286 ? 131.106 117.623 106.676 1.00 39.43  ? 286 LEU B CB  1 
ATOM 6647 C CG  . LEU D 4 286 ? 131.613 116.245 107.108 1.00 39.43  ? 286 LEU B CG  1 
ATOM 6648 C CD1 . LEU D 4 286 ? 132.547 115.646 106.064 1.00 39.43  ? 286 LEU B CD1 1 
ATOM 6649 C CD2 . LEU D 4 286 ? 132.297 116.323 108.464 1.00 39.43  ? 286 LEU B CD2 1 
ATOM 6650 N N   . ALA D 4 287 ? 128.257 119.557 106.119 1.00 39.49  ? 287 ALA B N   1 
ATOM 6651 C CA  . ALA D 4 287 ? 127.728 120.874 105.799 1.00 39.49  ? 287 ALA B CA  1 
ATOM 6652 C C   . ALA D 4 287 ? 127.540 121.668 107.081 1.00 39.49  ? 287 ALA B C   1 
ATOM 6653 O O   . ALA D 4 287 ? 126.956 121.168 108.049 1.00 39.49  ? 287 ALA B O   1 
ATOM 6654 C CB  . ALA D 4 287 ? 126.401 120.770 105.041 1.00 39.49  ? 287 ALA B CB  1 
ATOM 6655 N N   . GLY D 4 288 ? 128.032 122.902 107.080 1.00 40.34  ? 288 GLY B N   1 
ATOM 6656 C CA  . GLY D 4 288 ? 127.851 123.813 108.197 1.00 40.34  ? 288 GLY B CA  1 
ATOM 6657 C C   . GLY D 4 288 ? 126.677 124.741 107.941 1.00 40.34  ? 288 GLY B C   1 
ATOM 6658 O O   . GLY D 4 288 ? 126.531 125.289 106.849 1.00 40.34  ? 288 GLY B O   1 
ATOM 6659 N N   . TYR D 4 289 ? 125.846 124.910 108.961 1.00 45.43  ? 289 TYR B N   1 
ATOM 6660 C CA  . TYR D 4 289 ? 124.631 125.706 108.869 1.00 45.43  ? 289 TYR B CA  1 
ATOM 6661 C C   . TYR D 4 289 ? 124.743 126.929 109.773 1.00 45.43  ? 289 TYR B C   1 
ATOM 6662 O O   . TYR D 4 289 ? 125.746 127.139 110.459 1.00 45.43  ? 289 TYR B O   1 
ATOM 6663 C CB  . TYR D 4 289 ? 123.405 124.867 109.238 1.00 45.43  ? 289 TYR B CB  1 
ATOM 6664 C CG  . TYR D 4 289 ? 122.936 123.935 108.146 1.00 45.43  ? 289 TYR B CG  1 
ATOM 6665 C CD1 . TYR D 4 289 ? 123.643 122.781 107.838 1.00 45.43  ? 289 TYR B CD1 1 
ATOM 6666 C CD2 . TYR D 4 289 ? 121.781 124.205 107.426 1.00 45.43  ? 289 TYR B CD2 1 
ATOM 6667 C CE1 . TYR D 4 289 ? 123.214 121.925 106.841 1.00 45.43  ? 289 TYR B CE1 1 
ATOM 6668 C CE2 . TYR D 4 289 ? 121.343 123.354 106.429 1.00 45.43  ? 289 TYR B CE2 1 
ATOM 6669 C CZ  . TYR D 4 289 ? 122.064 122.216 106.141 1.00 45.43  ? 289 TYR B CZ  1 
ATOM 6670 O OH  . TYR D 4 289 ? 121.633 121.367 105.148 1.00 45.43  ? 289 TYR B OH  1 
ATOM 6671 N N   . ASP D 4 290 ? 123.691 127.743 109.764 1.00 49.63  ? 290 ASP B N   1 
ATOM 6672 C CA  . ASP D 4 290 ? 123.603 128.926 110.608 1.00 49.63  ? 290 ASP B CA  1 
ATOM 6673 C C   . ASP D 4 290 ? 122.921 128.648 111.941 1.00 49.63  ? 290 ASP B C   1 
ATOM 6674 O O   . ASP D 4 290 ? 122.699 129.585 112.715 1.00 49.63  ? 290 ASP B O   1 
ATOM 6675 C CB  . ASP D 4 290 ? 122.862 130.046 109.869 1.00 49.63  ? 290 ASP B CB  1 
ATOM 6676 C CG  . ASP D 4 290 ? 123.219 131.424 110.388 1.00 49.63  ? 290 ASP B CG  1 
ATOM 6677 O OD1 . ASP D 4 290 ? 124.152 131.529 111.212 1.00 49.63  ? 290 ASP B OD1 1 
ATOM 6678 O OD2 . ASP D 4 290 ? 122.565 132.404 109.973 1.00 49.63  ? 290 ASP B OD2 1 
ATOM 6679 N N   . ASP D 4 291 ? 122.587 127.388 112.231 1.00 51.14  ? 291 ASP B N   1 
ATOM 6680 C CA  . ASP D 4 291 ? 121.952 127.014 113.489 1.00 51.14  ? 291 ASP B CA  1 
ATOM 6681 C C   . ASP D 4 291 ? 122.964 126.634 114.561 1.00 51.14  ? 291 ASP B C   1 
ATOM 6682 O O   . ASP D 4 291 ? 122.664 125.793 115.421 1.00 51.14  ? 291 ASP B O   1 
ATOM 6683 C CB  . ASP D 4 291 ? 120.960 125.872 113.265 1.00 51.14  ? 291 ASP B CB  1 
ATOM 6684 C CG  . ASP D 4 291 ? 121.625 124.608 112.751 1.00 51.14  ? 291 ASP B CG  1 
ATOM 6685 O OD1 . ASP D 4 291 ? 122.806 124.669 112.350 1.00 51.14  ? 291 ASP B OD1 1 
ATOM 6686 O OD2 . ASP D 4 291 ? 120.964 123.548 112.750 1.00 51.14  ? 291 ASP B OD2 1 
ATOM 6687 N N   . PHE D 4 292 ? 124.163 127.217 114.515 1.00 49.68  ? 292 PHE B N   1 
ATOM 6688 C CA  . PHE D 4 292 ? 125.224 126.997 115.493 1.00 49.68  ? 292 PHE B CA  1 
ATOM 6689 C C   . PHE D 4 292 ? 125.732 125.561 115.481 1.00 49.68  ? 292 PHE B C   1 
ATOM 6690 O O   . PHE D 4 292 ? 126.290 125.092 116.477 1.00 49.68  ? 292 PHE B O   1 
ATOM 6691 C CB  . PHE D 4 292 ? 124.762 127.375 116.908 1.00 49.68  ? 292 PHE B CB  1 
ATOM 6692 C CG  . PHE D 4 292 ? 124.719 128.858 117.166 1.00 49.68  ? 292 PHE B CG  1 
ATOM 6693 C CD1 . PHE D 4 292 ? 125.325 129.398 118.287 1.00 49.68  ? 292 PHE B CD1 1 
ATOM 6694 C CD2 . PHE D 4 292 ? 124.062 129.711 116.293 1.00 49.68  ? 292 PHE B CD2 1 
ATOM 6695 C CE1 . PHE D 4 292 ? 125.278 130.759 118.530 1.00 49.68  ? 292 PHE B CE1 1 
ATOM 6696 C CE2 . PHE D 4 292 ? 124.016 131.071 116.529 1.00 49.68  ? 292 PHE B CE2 1 
ATOM 6697 C CZ  . PHE D 4 292 ? 124.626 131.596 117.648 1.00 49.68  ? 292 PHE B CZ  1 
ATOM 6698 N N   . ASN D 4 293 ? 125.551 124.848 114.369 1.00 45.29  ? 293 ASN B N   1 
ATOM 6699 C CA  . ASN D 4 293 ? 125.860 123.427 114.318 1.00 45.29  ? 293 ASN B CA  1 
ATOM 6700 C C   . ASN D 4 293 ? 126.220 123.030 112.893 1.00 45.29  ? 293 ASN B C   1 
ATOM 6701 O O   . ASN D 4 293 ? 125.824 123.683 111.923 1.00 45.29  ? 293 ASN B O   1 
ATOM 6702 C CB  . ASN D 4 293 ? 124.680 122.593 114.832 1.00 45.29  ? 293 ASN B CB  1 
ATOM 6703 C CG  . ASN D 4 293 ? 125.035 121.135 115.031 1.00 45.29  ? 293 ASN B CG  1 
ATOM 6704 O OD1 . ASN D 4 293 ? 126.206 120.757 114.997 1.00 45.29  ? 293 ASN B OD1 1 
ATOM 6705 N ND2 . ASN D 4 293 ? 124.022 120.306 115.246 1.00 45.29  ? 293 ASN B ND2 1 
ATOM 6706 N N   . CYS D 4 294 ? 126.979 121.942 112.783 1.00 42.67  ? 294 CYS B N   1 
ATOM 6707 C CA  . CYS D 4 294 ? 127.359 121.343 111.511 1.00 42.67  ? 294 CYS B CA  1 
ATOM 6708 C C   . CYS D 4 294 ? 126.908 119.890 111.491 1.00 42.67  ? 294 CYS B C   1 
ATOM 6709 O O   . CYS D 4 294 ? 127.019 119.187 112.501 1.00 42.67  ? 294 CYS B O   1 
ATOM 6710 C CB  . CYS D 4 294 ? 128.873 121.426 111.291 1.00 42.67  ? 294 CYS B CB  1 
ATOM 6711 S SG  . CYS D 4 294 ? 129.480 120.454 109.895 1.00 42.67  ? 294 CYS B SG  1 
ATOM 6712 N N   . ASN D 4 295 ? 126.400 119.436 110.346 1.00 45.01  ? 295 ASN B N   1 
ATOM 6713 C CA  . ASN D 4 295 ? 125.833 118.098 110.248 1.00 45.01  ? 295 ASN B CA  1 
ATOM 6714 C C   . ASN D 4 295 ? 126.416 117.346 109.059 1.00 45.01  ? 295 ASN B C   1 
ATOM 6715 O O   . ASN D 4 295 ? 126.826 117.941 108.058 1.00 45.01  ? 295 ASN B O   1 
ATOM 6716 C CB  . ASN D 4 295 ? 124.299 118.141 110.138 1.00 45.01  ? 295 ASN B CB  1 
ATOM 6717 C CG  . ASN D 4 295 ? 123.816 119.017 109.000 1.00 45.01  ? 295 ASN B CG  1 
ATOM 6718 O OD1 . ASN D 4 295 ? 124.613 119.631 108.292 1.00 45.01  ? 295 ASN B OD1 1 
ATOM 6719 N ND2 . ASN D 4 295 ? 122.503 119.079 108.819 1.00 45.01  ? 295 ASN B ND2 1 
ATOM 6720 N N   . VAL D 4 296 ? 126.432 116.021 109.179 1.00 46.13  ? 296 VAL B N   1 
ATOM 6721 C CA  . VAL D 4 296 ? 126.958 115.128 108.154 1.00 46.13  ? 296 VAL B CA  1 
ATOM 6722 C C   . VAL D 4 296 ? 125.787 114.424 107.485 1.00 46.13  ? 296 VAL B C   1 
ATOM 6723 O O   . VAL D 4 296 ? 124.908 113.881 108.166 1.00 46.13  ? 296 VAL B O   1 
ATOM 6724 C CB  . VAL D 4 296 ? 127.946 114.109 108.747 1.00 46.13  ? 296 VAL B CB  1 
ATOM 6725 C CG1 . VAL D 4 296 ? 128.598 113.295 107.641 1.00 46.13  ? 296 VAL B CG1 1 
ATOM 6726 C CG2 . VAL D 4 296 ? 128.997 114.817 109.589 1.00 46.13  ? 296 VAL B CG2 1 
ATOM 6727 N N   . TRP D 4 297 ? 125.776 114.433 106.156 1.00 48.65  ? 297 TRP B N   1 
ATOM 6728 C CA  . TRP D 4 297 ? 124.739 113.801 105.359 1.00 48.65  ? 297 TRP B CA  1 
ATOM 6729 C C   . TRP D 4 297 ? 125.314 112.611 104.601 1.00 48.65  ? 297 TRP B C   1 
ATOM 6730 O O   . TRP D 4 297 ? 126.470 112.627 104.167 1.00 48.65  ? 297 TRP B O   1 
ATOM 6731 C CB  . TRP D 4 297 ? 124.128 114.789 104.359 1.00 48.65  ? 297 TRP B CB  1 
ATOM 6732 C CG  . TRP D 4 297 ? 123.487 115.987 104.987 1.00 48.65  ? 297 TRP B CG  1 
ATOM 6733 C CD1 . TRP D 4 297 ? 124.111 117.125 105.408 1.00 48.65  ? 297 TRP B CD1 1 
ATOM 6734 C CD2 . TRP D 4 297 ? 122.091 116.174 105.249 1.00 48.65  ? 297 TRP B CD2 1 
ATOM 6735 N NE1 . TRP D 4 297 ? 123.191 118.005 105.925 1.00 48.65  ? 297 TRP B NE1 1 
ATOM 6736 C CE2 . TRP D 4 297 ? 121.944 117.446 105.838 1.00 48.65  ? 297 TRP B CE2 1 
ATOM 6737 C CE3 . TRP D 4 297 ? 120.953 115.389 105.047 1.00 48.65  ? 297 TRP B CE3 1 
ATOM 6738 C CZ2 . TRP D 4 297 ? 120.705 117.949 106.226 1.00 48.65  ? 297 TRP B CZ2 1 
ATOM 6739 C CZ3 . TRP D 4 297 ? 119.724 115.890 105.433 1.00 48.65  ? 297 TRP B CZ3 1 
ATOM 6740 C CH2 . TRP D 4 297 ? 119.610 117.158 106.016 1.00 48.65  ? 297 TRP B CH2 1 
ATOM 6741 N N   . ASP D 4 298 ? 124.494 111.574 104.452 1.00 59.34  ? 298 ASP B N   1 
ATOM 6742 C CA  . ASP D 4 298 ? 124.834 110.442 103.598 1.00 59.34  ? 298 ASP B CA  1 
ATOM 6743 C C   . ASP D 4 298 ? 124.641 110.871 102.150 1.00 59.34  ? 298 ASP B C   1 
ATOM 6744 O O   . ASP D 4 298 ? 123.512 111.123 101.715 1.00 59.34  ? 298 ASP B O   1 
ATOM 6745 C CB  . ASP D 4 298 ? 123.971 109.231 103.939 1.00 59.34  ? 298 ASP B CB  1 
ATOM 6746 C CG  . ASP D 4 298 ? 124.265 108.676 105.318 1.00 59.34  ? 298 ASP B CG  1 
ATOM 6747 O OD1 . ASP D 4 298 ? 125.121 109.251 106.022 1.00 59.34  ? 298 ASP B OD1 1 
ATOM 6748 O OD2 . ASP D 4 298 ? 123.638 107.665 105.699 1.00 59.34  ? 298 ASP B OD2 1 
ATOM 6749 N N   . ALA D 4 299 ? 125.741 110.959 101.400 1.00 56.84  ? 299 ALA B N   1 
ATOM 6750 C CA  . ALA D 4 299 ? 125.688 111.500 100.048 1.00 56.84  ? 299 ALA B CA  1 
ATOM 6751 C C   . ALA D 4 299 ? 124.911 110.621 99.078  1.00 56.84  ? 299 ALA B C   1 
ATOM 6752 O O   . ALA D 4 299 ? 124.547 111.099 97.998  1.00 56.84  ? 299 ALA B O   1 
ATOM 6753 C CB  . ALA D 4 299 ? 127.103 111.725 99.516  1.00 56.84  ? 299 ALA B CB  1 
ATOM 6754 N N   . LEU D 4 300 ? 124.648 109.364 99.425  1.00 67.31  ? 300 LEU B N   1 
ATOM 6755 C CA  . LEU D 4 300 ? 123.930 108.451 98.547  1.00 67.31  ? 300 LEU B CA  1 
ATOM 6756 C C   . LEU D 4 300 ? 122.547 108.087 99.068  1.00 67.31  ? 300 LEU B C   1 
ATOM 6757 O O   . LEU D 4 300 ? 121.820 107.355 98.388  1.00 67.31  ? 300 LEU B O   1 
ATOM 6758 C CB  . LEU D 4 300 ? 124.751 107.175 98.324  1.00 67.31  ? 300 LEU B CB  1 
ATOM 6759 C CG  . LEU D 4 300 ? 125.663 107.137 97.094  1.00 67.31  ? 300 LEU B CG  1 
ATOM 6760 C CD1 . LEU D 4 300 ? 124.839 107.094 95.817  1.00 67.31  ? 300 LEU B CD1 1 
ATOM 6761 C CD2 . LEU D 4 300 ? 126.623 108.316 97.073  1.00 67.31  ? 300 LEU B CD2 1 
ATOM 6762 N N   . LYS D 4 301 ? 122.162 108.575 100.247 1.00 67.27  ? 301 LYS B N   1 
ATOM 6763 C CA  . LYS D 4 301 ? 120.856 108.257 100.807 1.00 67.27  ? 301 LYS B CA  1 
ATOM 6764 C C   . LYS D 4 301 ? 120.122 109.463 101.374 1.00 67.27  ? 301 LYS B C   1 
ATOM 6765 O O   . LYS D 4 301 ? 119.002 109.298 101.868 1.00 67.27  ? 301 LYS B O   1 
ATOM 6766 C CB  . LYS D 4 301 ? 120.993 107.186 101.902 1.00 67.27  ? 301 LYS B CB  1 
ATOM 6767 C CG  . LYS D 4 301 ? 121.101 105.767 101.369 1.00 67.27  ? 301 LYS B CG  1 
ATOM 6768 C CD  . LYS D 4 301 ? 121.058 104.749 102.496 1.00 67.27  ? 301 LYS B CD  1 
ATOM 6769 C CE  . LYS D 4 301 ? 119.644 104.569 103.023 1.00 67.27  ? 301 LYS B CE  1 
ATOM 6770 N NZ  . LYS D 4 301 ? 118.957 103.411 102.387 1.00 67.27  ? 301 LYS B NZ  1 
ATOM 6771 N N   . ALA D 4 302 ? 120.719 110.658 101.340 1.00 61.35  ? 302 ALA B N   1 
ATOM 6772 C CA  . ALA D 4 302 ? 120.083 111.900 101.771 1.00 61.35  ? 302 ALA B CA  1 
ATOM 6773 C C   . ALA D 4 302 ? 119.709 111.883 103.250 1.00 61.35  ? 302 ALA B C   1 
ATOM 6774 O O   . ALA D 4 302 ? 118.943 112.736 103.708 1.00 61.35  ? 302 ALA B O   1 
ATOM 6775 C CB  . ALA D 4 302 ? 118.844 112.195 100.920 1.00 61.35  ? 302 ALA B CB  1 
ATOM 6776 N N   . ASP D 4 303 ? 120.240 110.924 104.004 1.00 59.71  ? 303 ASP B N   1 
ATOM 6777 C CA  . ASP D 4 303 ? 119.996 110.872 105.435 1.00 59.71  ? 303 ASP B CA  1 
ATOM 6778 C C   . ASP D 4 303 ? 121.105 111.602 106.191 1.00 59.71  ? 303 ASP B C   1 
ATOM 6779 O O   . ASP D 4 303 ? 122.155 111.939 105.640 1.00 59.71  ? 303 ASP B O   1 
ATOM 6780 C CB  . ASP D 4 303 ? 119.889 109.425 105.912 1.00 59.71  ? 303 ASP B CB  1 
ATOM 6781 C CG  . ASP D 4 303 ? 119.004 108.580 105.017 1.00 59.71  ? 303 ASP B CG  1 
ATOM 6782 O OD1 . ASP D 4 303 ? 117.915 109.058 104.634 1.00 59.71  ? 303 ASP B OD1 1 
ATOM 6783 O OD2 . ASP D 4 303 ? 119.394 107.436 104.703 1.00 59.71  ? 303 ASP B OD2 1 
ATOM 6784 N N   . ARG D 4 304 ? 120.859 111.845 107.475 1.00 59.63  ? 304 ARG B N   1 
ATOM 6785 C CA  . ARG D 4 304 ? 121.812 112.523 108.342 1.00 59.63  ? 304 ARG B CA  1 
ATOM 6786 C C   . ARG D 4 304 ? 122.484 111.503 109.252 1.00 59.63  ? 304 ARG B C   1 
ATOM 6787 O O   . ARG D 4 304 ? 121.804 110.730 109.935 1.00 59.63  ? 304 ARG B O   1 
ATOM 6788 C CB  . ARG D 4 304 ? 121.120 113.604 109.174 1.00 59.63  ? 304 ARG B CB  1 
ATOM 6789 C CG  . ARG D 4 304 ? 121.933 114.878 109.335 1.00 59.63  ? 304 ARG B CG  1 
ATOM 6790 C CD  . ARG D 4 304 ? 121.507 115.653 110.571 1.00 59.63  ? 304 ARG B CD  1 
ATOM 6791 N NE  . ARG D 4 304 ? 120.062 115.842 110.625 1.00 59.63  ? 304 ARG B NE  1 
ATOM 6792 C CZ  . ARG D 4 304 ? 119.413 116.365 111.657 1.00 59.63  ? 304 ARG B CZ  1 
ATOM 6793 N NH1 . ARG D 4 304 ? 120.052 116.766 112.744 1.00 59.63  ? 304 ARG B NH1 1 
ATOM 6794 N NH2 . ARG D 4 304 ? 118.091 116.490 111.596 1.00 59.63  ? 304 ARG B NH2 1 
ATOM 6795 N N   . ALA D 4 305 ? 123.818 111.504 109.256 1.00 57.89  ? 305 ALA B N   1 
ATOM 6796 C CA  . ALA D 4 305 ? 124.585 110.541 110.034 1.00 57.89  ? 305 ALA B CA  1 
ATOM 6797 C C   . ALA D 4 305 ? 125.041 111.073 111.385 1.00 57.89  ? 305 ALA B C   1 
ATOM 6798 O O   . ALA D 4 305 ? 125.402 110.273 112.255 1.00 57.89  ? 305 ALA B O   1 
ATOM 6799 C CB  . ALA D 4 305 ? 125.812 110.075 109.241 1.00 57.89  ? 305 ALA B CB  1 
ATOM 6800 N N   . GLY D 4 306 ? 125.040 112.384 111.582 1.00 48.43  ? 306 GLY B N   1 
ATOM 6801 C CA  . GLY D 4 306 ? 125.451 112.942 112.855 1.00 48.43  ? 306 GLY B CA  1 
ATOM 6802 C C   . GLY D 4 306 ? 125.544 114.447 112.775 1.00 48.43  ? 306 GLY B C   1 
ATOM 6803 O O   . GLY D 4 306 ? 125.416 115.051 111.707 1.00 48.43  ? 306 GLY B O   1 
ATOM 6804 N N   . VAL D 4 307 ? 125.772 115.049 113.939 1.00 44.65  ? 307 VAL B N   1 
ATOM 6805 C CA  . VAL D 4 307 ? 125.901 116.494 114.069 1.00 44.65  ? 307 VAL B CA  1 
ATOM 6806 C C   . VAL D 4 307 ? 127.202 116.809 114.796 1.00 44.65  ? 307 VAL B C   1 
ATOM 6807 O O   . VAL D 4 307 ? 127.576 116.122 115.753 1.00 44.65  ? 307 VAL B O   1 
ATOM 6808 C CB  . VAL D 4 307 ? 124.689 117.116 114.800 1.00 44.65  ? 307 VAL B CB  1 
ATOM 6809 C CG1 . VAL D 4 307 ? 123.401 116.801 114.055 1.00 44.65  ? 307 VAL B CG1 1 
ATOM 6810 C CG2 . VAL D 4 307 ? 124.598 116.617 116.235 1.00 44.65  ? 307 VAL B CG2 1 
ATOM 6811 N N   . LEU D 4 308 ? 127.907 117.828 114.317 1.00 40.11  ? 308 LEU B N   1 
ATOM 6812 C CA  . LEU D 4 308 ? 129.153 118.275 114.940 1.00 40.11  ? 308 LEU B CA  1 
ATOM 6813 C C   . LEU D 4 308 ? 128.897 119.478 115.847 1.00 40.11  ? 308 LEU B C   1 
ATOM 6814 O O   . LEU D 4 308 ? 129.390 120.584 115.623 1.00 40.11  ? 308 LEU B O   1 
ATOM 6815 C CB  . LEU D 4 308 ? 130.193 118.597 113.869 1.00 40.11  ? 308 LEU B CB  1 
ATOM 6816 C CG  . LEU D 4 308 ? 130.509 117.487 112.865 1.00 40.11  ? 308 LEU B CG  1 
ATOM 6817 C CD1 . LEU D 4 308 ? 131.699 117.871 111.999 1.00 40.11  ? 308 LEU B CD1 1 
ATOM 6818 C CD2 . LEU D 4 308 ? 130.766 116.170 113.579 1.00 40.11  ? 308 LEU B CD2 1 
ATOM 6819 N N   . ALA D 4 309 ? 128.107 119.242 116.890 1.00 41.49  ? 309 ALA B N   1 
ATOM 6820 C CA  . ALA D 4 309 ? 127.786 120.297 117.839 1.00 41.49  ? 309 ALA B CA  1 
ATOM 6821 C C   . ALA D 4 309 ? 128.973 120.580 118.753 1.00 41.49  ? 309 ALA B C   1 
ATOM 6822 O O   . ALA D 4 309 ? 129.782 119.698 119.051 1.00 41.49  ? 309 ALA B O   1 
ATOM 6823 C CB  . ALA D 4 309 ? 126.563 119.915 118.671 1.00 41.49  ? 309 ALA B CB  1 
ATOM 6824 N N   . GLY D 4 310 ? 129.068 121.828 119.204 1.00 42.25  ? 310 GLY B N   1 
ATOM 6825 C CA  . GLY D 4 310 ? 130.151 122.223 120.081 1.00 42.25  ? 310 GLY B CA  1 
ATOM 6826 C C   . GLY D 4 310 ? 130.667 123.623 119.825 1.00 42.25  ? 310 GLY B C   1 
ATOM 6827 O O   . GLY D 4 310 ? 131.493 124.133 120.588 1.00 42.25  ? 310 GLY B O   1 
ATOM 6828 N N   . HIS D 4 311 ? 130.191 124.257 118.758 1.00 40.45  ? 311 HIS B N   1 
ATOM 6829 C CA  . HIS D 4 311 ? 130.605 125.606 118.399 1.00 40.45  ? 311 HIS B CA  1 
ATOM 6830 C C   . HIS D 4 311 ? 129.638 126.615 119.005 1.00 40.45  ? 311 HIS B C   1 
ATOM 6831 O O   . HIS D 4 311 ? 128.420 126.412 118.976 1.00 40.45  ? 311 HIS B O   1 
ATOM 6832 C CB  . HIS D 4 311 ? 130.671 125.773 116.881 1.00 40.45  ? 311 HIS B CB  1 
ATOM 6833 C CG  . HIS D 4 311 ? 131.902 125.187 116.263 1.00 40.45  ? 311 HIS B CG  1 
ATOM 6834 N ND1 . HIS D 4 311 ? 133.112 125.846 116.245 1.00 40.45  ? 311 HIS B ND1 1 
ATOM 6835 C CD2 . HIS D 4 311 ? 132.111 124.000 115.646 1.00 40.45  ? 311 HIS B CD2 1 
ATOM 6836 C CE1 . HIS D 4 311 ? 134.013 125.093 115.641 1.00 40.45  ? 311 HIS B CE1 1 
ATOM 6837 N NE2 . HIS D 4 311 ? 133.432 123.967 115.268 1.00 40.45  ? 311 HIS B NE2 1 
ATOM 6838 N N   . ASP D 4 312 ? 130.187 127.700 119.551 1.00 48.19  ? 312 ASP B N   1 
ATOM 6839 C CA  . ASP D 4 312 ? 129.390 128.704 120.242 1.00 48.19  ? 312 ASP B CA  1 
ATOM 6840 C C   . ASP D 4 312 ? 128.783 129.732 119.292 1.00 48.19  ? 312 ASP B C   1 
ATOM 6841 O O   . ASP D 4 312 ? 128.038 130.608 119.744 1.00 48.19  ? 312 ASP B O   1 
ATOM 6842 C CB  . ASP D 4 312 ? 130.257 129.401 121.300 1.00 48.19  ? 312 ASP B CB  1 
ATOM 6843 C CG  . ASP D 4 312 ? 129.471 130.364 122.171 1.00 48.19  ? 312 ASP B CG  1 
ATOM 6844 O OD1 . ASP D 4 312 ? 128.709 129.895 123.042 1.00 48.19  ? 312 ASP B OD1 1 
ATOM 6845 O OD2 . ASP D 4 312 ? 129.615 131.590 121.982 1.00 48.19  ? 312 ASP B OD2 1 
ATOM 6846 N N   . ASN D 4 313 ? 129.062 129.639 117.995 1.00 44.39  ? 313 ASN B N   1 
ATOM 6847 C CA  . ASN D 4 313 ? 128.517 130.572 117.017 1.00 44.39  ? 313 ASN B CA  1 
ATOM 6848 C C   . ASN D 4 313 ? 128.320 129.825 115.701 1.00 44.39  ? 313 ASN B C   1 
ATOM 6849 O O   . ASN D 4 313 ? 128.467 128.600 115.632 1.00 44.39  ? 313 ASN B O   1 
ATOM 6850 C CB  . ASN D 4 313 ? 129.430 131.796 116.866 1.00 44.39  ? 313 ASN B CB  1 
ATOM 6851 C CG  . ASN D 4 313 ? 128.657 133.065 116.566 1.00 44.39  ? 313 ASN B CG  1 
ATOM 6852 O OD1 . ASN D 4 313 ? 127.571 133.022 115.989 1.00 44.39  ? 313 ASN B OD1 1 
ATOM 6853 N ND2 . ASN D 4 313 ? 129.213 134.204 116.961 1.00 44.39  ? 313 ASN B ND2 1 
ATOM 6854 N N   . ARG D 4 314 ? 127.977 130.569 114.652 1.00 42.80  ? 314 ARG B N   1 
ATOM 6855 C CA  . ARG D 4 314 ? 127.747 129.964 113.346 1.00 42.80  ? 314 ARG B CA  1 
ATOM 6856 C C   . ARG D 4 314 ? 129.037 129.373 112.795 1.00 42.80  ? 314 ARG B C   1 
ATOM 6857 O O   . ARG D 4 314 ? 130.078 130.035 112.772 1.00 42.80  ? 314 ARG B O   1 
ATOM 6858 C CB  . ARG D 4 314 ? 127.187 131.002 112.373 1.00 42.80  ? 314 ARG B CB  1 
ATOM 6859 C CG  . ARG D 4 314 ? 127.426 130.659 110.909 1.00 42.80  ? 314 ARG B CG  1 
ATOM 6860 C CD  . ARG D 4 314 ? 127.363 131.891 110.021 1.00 42.80  ? 314 ARG B CD  1 
ATOM 6861 N NE  . ARG D 4 314 ? 126.126 132.640 110.204 1.00 42.80  ? 314 ARG B NE  1 
ATOM 6862 C CZ  . ARG D 4 314 ? 125.670 133.550 109.355 1.00 42.80  ? 314 ARG B CZ  1 
ATOM 6863 N NH1 . ARG D 4 314 ? 126.328 133.854 108.248 1.00 42.80  ? 314 ARG B NH1 1 
ATOM 6864 N NH2 . ARG D 4 314 ? 124.524 134.169 109.621 1.00 42.80  ? 314 ARG B NH2 1 
ATOM 6865 N N   . VAL D 4 315 ? 128.962 128.125 112.336 1.00 38.99  ? 315 VAL B N   1 
ATOM 6866 C CA  . VAL D 4 315 ? 130.108 127.442 111.740 1.00 38.99  ? 315 VAL B CA  1 
ATOM 6867 C C   . VAL D 4 315 ? 130.308 128.016 110.339 1.00 38.99  ? 315 VAL B C   1 
ATOM 6868 O O   . VAL D 4 315 ? 129.602 127.663 109.393 1.00 38.99  ? 315 VAL B O   1 
ATOM 6869 C CB  . VAL D 4 315 ? 129.926 125.922 111.727 1.00 38.99  ? 315 VAL B CB  1 
ATOM 6870 C CG1 . VAL D 4 315 ? 130.128 125.369 113.124 1.00 38.99  ? 315 VAL B CG1 1 
ATOM 6871 C CG2 . VAL D 4 315 ? 128.530 125.552 111.253 1.00 38.99  ? 315 VAL B CG2 1 
ATOM 6872 N N   . SER D 4 316 ? 131.276 128.924 110.207 1.00 36.00  ? 316 SER B N   1 
ATOM 6873 C CA  . SER D 4 316 ? 131.464 129.638 108.950 1.00 36.00  ? 316 SER B CA  1 
ATOM 6874 C C   . SER D 4 316 ? 132.149 128.778 107.895 1.00 36.00  ? 316 SER B C   1 
ATOM 6875 O O   . SER D 4 316 ? 131.807 128.861 106.710 1.00 36.00  ? 316 SER B O   1 
ATOM 6876 C CB  . SER D 4 316 ? 132.266 130.917 109.191 1.00 36.00  ? 316 SER B CB  1 
ATOM 6877 O OG  . SER D 4 316 ? 133.589 130.620 109.600 1.00 36.00  ? 316 SER B OG  1 
ATOM 6878 N N   . CYS D 4 317 ? 133.114 127.950 108.294 1.00 33.41  ? 317 CYS B N   1 
ATOM 6879 C CA  . CYS D 4 317 ? 133.904 127.216 107.318 1.00 33.41  ? 317 CYS B CA  1 
ATOM 6880 C C   . CYS D 4 317 ? 134.248 125.836 107.857 1.00 33.41  ? 317 CYS B C   1 
ATOM 6881 O O   . CYS D 4 317 ? 134.277 125.607 109.069 1.00 33.41  ? 317 CYS B O   1 
ATOM 6882 C CB  . CYS D 4 317 ? 135.185 127.976 106.955 1.00 33.41  ? 317 CYS B CB  1 
ATOM 6883 S SG  . CYS D 4 317 ? 136.213 128.412 108.376 1.00 33.41  ? 317 CYS B SG  1 
ATOM 6884 N N   . LEU D 4 318 ? 134.523 124.919 106.934 1.00 31.51  ? 318 LEU B N   1 
ATOM 6885 C CA  . LEU D 4 318 ? 134.945 123.573 107.292 1.00 31.51  ? 318 LEU B CA  1 
ATOM 6886 C C   . LEU D 4 318 ? 135.727 122.983 106.128 1.00 31.51  ? 318 LEU B C   1 
ATOM 6887 O O   . LEU D 4 318 ? 135.603 123.425 104.983 1.00 31.51  ? 318 LEU B O   1 
ATOM 6888 C CB  . LEU D 4 318 ? 133.746 122.693 107.672 1.00 31.51  ? 318 LEU B CB  1 
ATOM 6889 C CG  . LEU D 4 318 ? 132.631 122.433 106.653 1.00 31.51  ? 318 LEU B CG  1 
ATOM 6890 C CD1 . LEU D 4 318 ? 132.941 121.248 105.753 1.00 31.51  ? 318 LEU B CD1 1 
ATOM 6891 C CD2 . LEU D 4 318 ? 131.303 122.233 107.363 1.00 31.51  ? 318 LEU B CD2 1 
ATOM 6892 N N   . GLY D 4 319 ? 136.538 121.977 106.441 1.00 30.87  ? 319 GLY B N   1 
ATOM 6893 C CA  . GLY D 4 319 ? 137.383 121.355 105.440 1.00 30.87  ? 319 GLY B CA  1 
ATOM 6894 C C   . GLY D 4 319 ? 137.788 119.964 105.858 1.00 30.87  ? 319 GLY B C   1 
ATOM 6895 O O   . GLY D 4 319 ? 137.837 119.643 107.050 1.00 30.87  ? 319 GLY B O   1 
ATOM 6896 N N   . VAL D 4 320 ? 138.082 119.127 104.867 1.00 33.46  ? 320 VAL B N   1 
ATOM 6897 C CA  . VAL D 4 320 ? 138.472 117.739 105.082 1.00 33.46  ? 320 VAL B CA  1 
ATOM 6898 C C   . VAL D 4 320 ? 139.871 117.534 104.518 1.00 33.46  ? 320 VAL B C   1 
ATOM 6899 O O   . VAL D 4 320 ? 140.201 118.054 103.446 1.00 33.46  ? 320 VAL B O   1 
ATOM 6900 C CB  . VAL D 4 320 ? 137.470 116.761 104.439 1.00 33.46  ? 320 VAL B CB  1 
ATOM 6901 C CG1 . VAL D 4 320 ? 137.779 115.329 104.852 1.00 33.46  ? 320 VAL B CG1 1 
ATOM 6902 C CG2 . VAL D 4 320 ? 136.045 117.132 104.818 1.00 33.46  ? 320 VAL B CG2 1 
ATOM 6903 N N   . THR D 4 321 ? 140.692 116.781 105.246 1.00 37.19  ? 321 THR B N   1 
ATOM 6904 C CA  . THR D 4 321 ? 142.058 116.523 104.821 1.00 37.19  ? 321 THR B CA  1 
ATOM 6905 C C   . THR D 4 321 ? 142.081 115.669 103.555 1.00 37.19  ? 321 THR B C   1 
ATOM 6906 O O   . THR D 4 321 ? 141.103 115.006 103.199 1.00 37.19  ? 321 THR B O   1 
ATOM 6907 C CB  . THR D 4 321 ? 142.846 115.820 105.926 1.00 37.19  ? 321 THR B CB  1 
ATOM 6908 O OG1 . THR D 4 321 ? 142.484 114.434 105.966 1.00 37.19  ? 321 THR B OG1 1 
ATOM 6909 C CG2 . THR D 4 321 ? 142.552 116.448 107.276 1.00 37.19  ? 321 THR B CG2 1 
ATOM 6910 N N   . ASP D 4 322 ? 143.226 115.701 102.868 1.00 43.65  ? 322 ASP B N   1 
ATOM 6911 C CA  . ASP D 4 322 ? 143.397 114.869 101.681 1.00 43.65  ? 322 ASP B CA  1 
ATOM 6912 C C   . ASP D 4 322 ? 143.315 113.390 102.033 1.00 43.65  ? 322 ASP B C   1 
ATOM 6913 O O   . ASP D 4 322 ? 142.713 112.600 101.296 1.00 43.65  ? 322 ASP B O   1 
ATOM 6914 C CB  . ASP D 4 322 ? 144.729 115.190 101.003 1.00 43.65  ? 322 ASP B CB  1 
ATOM 6915 C CG  . ASP D 4 322 ? 144.781 116.604 100.461 1.00 43.65  ? 322 ASP B CG  1 
ATOM 6916 O OD1 . ASP D 4 322 ? 144.842 117.552 101.272 1.00 43.65  ? 322 ASP B OD1 1 
ATOM 6917 O OD2 . ASP D 4 322 ? 144.760 116.769 99.223  1.00 43.65  ? 322 ASP B OD2 1 
ATOM 6918 N N   . ASP D 4 323 ? 143.917 112.995 103.157 1.00 44.72  ? 323 ASP B N   1 
ATOM 6919 C CA  . ASP D 4 323 ? 143.781 111.624 103.632 1.00 44.72  ? 323 ASP B CA  1 
ATOM 6920 C C   . ASP D 4 323 ? 142.396 111.348 104.201 1.00 44.72  ? 323 ASP B C   1 
ATOM 6921 O O   . ASP D 4 323 ? 142.037 110.181 104.385 1.00 44.72  ? 323 ASP B O   1 
ATOM 6922 C CB  . ASP D 4 323 ? 144.846 111.324 104.687 1.00 44.72  ? 323 ASP B CB  1 
ATOM 6923 N N   . GLY D 4 324 ? 141.618 112.390 104.489 1.00 45.81  ? 324 GLY B N   1 
ATOM 6924 C CA  . GLY D 4 324 ? 140.281 112.203 105.013 1.00 45.81  ? 324 GLY B CA  1 
ATOM 6925 C C   . GLY D 4 324 ? 140.224 111.673 106.425 1.00 45.81  ? 324 GLY B C   1 
ATOM 6926 O O   . GLY D 4 324 ? 139.181 111.166 106.843 1.00 45.81  ? 324 GLY B O   1 
ATOM 6927 N N   . MET D 4 325 ? 141.318 111.777 107.176 1.00 45.66  ? 325 MET B N   1 
ATOM 6928 C CA  . MET D 4 325 ? 141.381 111.235 108.526 1.00 45.66  ? 325 MET B CA  1 
ATOM 6929 C C   . MET D 4 325 ? 140.745 112.145 109.568 1.00 45.66  ? 325 MET B C   1 
ATOM 6930 O O   . MET D 4 325 ? 140.450 111.679 110.674 1.00 45.66  ? 325 MET B O   1 
ATOM 6931 C CB  . MET D 4 325 ? 142.839 110.954 108.907 1.00 45.66  ? 325 MET B CB  1 
ATOM 6932 C CG  . MET D 4 325 ? 143.011 109.946 110.032 1.00 45.66  ? 325 MET B CG  1 
ATOM 6933 S SD  . MET D 4 325 ? 144.613 109.122 109.980 1.00 45.66  ? 325 MET B SD  1 
ATOM 6934 C CE  . MET D 4 325 ? 144.399 108.051 108.561 1.00 45.66  ? 325 MET B CE  1 
ATOM 6935 N N   . ALA D 4 326 ? 140.515 113.416 109.248 1.00 37.27  ? 326 ALA B N   1 
ATOM 6936 C CA  . ALA D 4 326 ? 139.916 114.345 110.194 1.00 37.27  ? 326 ALA B CA  1 
ATOM 6937 C C   . ALA D 4 326 ? 139.245 115.472 109.424 1.00 37.27  ? 326 ALA B C   1 
ATOM 6938 O O   . ALA D 4 326 ? 139.519 115.691 108.242 1.00 37.27  ? 326 ALA B O   1 
ATOM 6939 C CB  . ALA D 4 326 ? 140.955 114.906 111.171 1.00 37.27  ? 326 ALA B CB  1 
ATOM 6940 N N   . VAL D 4 327 ? 138.355 116.186 110.110 1.00 32.87  ? 327 VAL B N   1 
ATOM 6941 C CA  . VAL D 4 327 ? 137.660 117.331 109.532 1.00 32.87  ? 327 VAL B CA  1 
ATOM 6942 C C   . VAL D 4 327 ? 137.813 118.519 110.474 1.00 32.87  ? 327 VAL B C   1 
ATOM 6943 O O   . VAL D 4 327 ? 137.606 118.392 111.684 1.00 32.87  ? 327 VAL B O   1 
ATOM 6944 C CB  . VAL D 4 327 ? 136.174 117.020 109.252 1.00 32.87  ? 327 VAL B CB  1 
ATOM 6945 C CG1 . VAL D 4 327 ? 135.453 116.581 110.514 1.00 32.87  ? 327 VAL B CG1 1 
ATOM 6946 C CG2 . VAL D 4 327 ? 135.481 118.228 108.642 1.00 32.87  ? 327 VAL B CG2 1 
ATOM 6947 N N   . ALA D 4 328 ? 138.201 119.665 109.925 1.00 30.61  ? 328 ALA B N   1 
ATOM 6948 C CA  . ALA D 4 328 ? 138.430 120.868 110.712 1.00 30.61  ? 328 ALA B CA  1 
ATOM 6949 C C   . ALA D 4 328 ? 137.324 121.875 110.443 1.00 30.61  ? 328 ALA B C   1 
ATOM 6950 O O   . ALA D 4 328 ? 137.037 122.194 109.285 1.00 30.61  ? 328 ALA B O   1 
ATOM 6951 C CB  . ALA D 4 328 ? 139.793 121.481 110.395 1.00 30.61  ? 328 ALA B CB  1 
ATOM 6952 N N   . THR D 4 329 ? 136.715 122.377 111.513 1.00 32.05  ? 329 THR B N   1 
ATOM 6953 C CA  . THR D 4 329 ? 135.619 123.332 111.426 1.00 32.05  ? 329 THR B CA  1 
ATOM 6954 C C   . THR D 4 329 ? 135.996 124.608 112.164 1.00 32.05  ? 329 THR B C   1 
ATOM 6955 O O   . THR D 4 329 ? 136.431 124.557 113.320 1.00 32.05  ? 329 THR B O   1 
ATOM 6956 C CB  . THR D 4 329 ? 134.329 122.747 112.010 1.00 32.05  ? 329 THR B CB  1 
ATOM 6957 O OG1 . THR D 4 329 ? 133.988 121.543 111.311 1.00 32.05  ? 329 THR B OG1 1 
ATOM 6958 C CG2 . THR D 4 329 ? 133.187 123.740 111.875 1.00 32.05  ? 329 THR B CG2 1 
ATOM 6959 N N   . GLY D 4 330 ? 135.837 125.739 111.494 1.00 32.55  ? 330 GLY B N   1 
ATOM 6960 C CA  . GLY D 4 330 ? 136.038 127.043 112.106 1.00 32.55  ? 330 GLY B CA  1 
ATOM 6961 C C   . GLY D 4 330 ? 134.743 127.834 112.079 1.00 32.55  ? 330 GLY B C   1 
ATOM 6962 O O   . GLY D 4 330 ? 134.042 127.853 111.064 1.00 32.55  ? 330 GLY B O   1 
ATOM 6963 N N   . SER D 4 331 ? 134.439 128.487 113.196 1.00 38.14  ? 331 SER B N   1 
ATOM 6964 C CA  . SER D 4 331 ? 133.177 129.186 113.379 1.00 38.14  ? 331 SER B CA  1 
ATOM 6965 C C   . SER D 4 331 ? 133.446 130.628 113.793 1.00 38.14  ? 331 SER B C   1 
ATOM 6966 O O   . SER D 4 331 ? 134.592 131.043 113.985 1.00 38.14  ? 331 SER B O   1 
ATOM 6967 C CB  . SER D 4 331 ? 132.303 128.476 114.421 1.00 38.14  ? 331 SER B CB  1 
ATOM 6968 O OG  . SER D 4 331 ? 131.307 129.346 114.929 1.00 38.14  ? 331 SER B OG  1 
ATOM 6969 N N   . TRP D 4 332 ? 132.363 131.396 113.930 1.00 40.52  ? 332 TRP B N   1 
ATOM 6970 C CA  . TRP D 4 332 ? 132.459 132.781 114.373 1.00 40.52  ? 332 TRP B CA  1 
ATOM 6971 C C   . TRP D 4 332 ? 132.810 132.906 115.850 1.00 40.52  ? 332 TRP B C   1 
ATOM 6972 O O   . TRP D 4 332 ? 133.086 134.019 116.310 1.00 40.52  ? 332 TRP B O   1 
ATOM 6973 C CB  . TRP D 4 332 ? 131.146 133.515 114.092 1.00 40.52  ? 332 TRP B CB  1 
ATOM 6974 C CG  . TRP D 4 332 ? 130.913 133.805 112.640 1.00 40.52  ? 332 TRP B CG  1 
ATOM 6975 C CD1 . TRP D 4 332 ? 131.695 133.421 111.591 1.00 40.52  ? 332 TRP B CD1 1 
ATOM 6976 C CD2 . TRP D 4 332 ? 129.823 134.546 112.077 1.00 40.52  ? 332 TRP B CD2 1 
ATOM 6977 N NE1 . TRP D 4 332 ? 131.161 133.875 110.410 1.00 40.52  ? 332 TRP B NE1 1 
ATOM 6978 C CE2 . TRP D 4 332 ? 130.010 134.568 110.681 1.00 40.52  ? 332 TRP B CE2 1 
ATOM 6979 C CE3 . TRP D 4 332 ? 128.706 135.191 112.618 1.00 40.52  ? 332 TRP B CE3 1 
ATOM 6980 C CZ2 . TRP D 4 332 ? 129.124 135.210 109.819 1.00 40.52  ? 332 TRP B CZ2 1 
ATOM 6981 C CZ3 . TRP D 4 332 ? 127.827 135.828 111.760 1.00 40.52  ? 332 TRP B CZ3 1 
ATOM 6982 C CH2 . TRP D 4 332 ? 128.041 135.833 110.376 1.00 40.52  ? 332 TRP B CH2 1 
ATOM 6983 N N   . ASP D 4 333 ? 132.806 131.804 116.598 1.00 42.09  ? 333 ASP B N   1 
ATOM 6984 C CA  . ASP D 4 333 ? 133.133 131.822 118.018 1.00 42.09  ? 333 ASP B CA  1 
ATOM 6985 C C   . ASP D 4 333 ? 134.633 131.889 118.284 1.00 42.09  ? 333 ASP B C   1 
ATOM 6986 O O   . ASP D 4 333 ? 135.048 131.682 119.430 1.00 42.09  ? 333 ASP B O   1 
ATOM 6987 C CB  . ASP D 4 333 ? 132.536 130.593 118.711 1.00 42.09  ? 333 ASP B CB  1 
ATOM 6988 C CG  . ASP D 4 333 ? 133.122 129.290 118.200 1.00 42.09  ? 333 ASP B CG  1 
ATOM 6989 O OD1 . ASP D 4 333 ? 133.766 129.298 117.131 1.00 42.09  ? 333 ASP B OD1 1 
ATOM 6990 O OD2 . ASP D 4 333 ? 132.936 128.253 118.872 1.00 42.09  ? 333 ASP B OD2 1 
ATOM 6991 N N   . SER D 4 334 ? 135.443 132.158 117.257 1.00 40.64  ? 334 SER B N   1 
ATOM 6992 C CA  . SER D 4 334 ? 136.890 132.326 117.404 1.00 40.64  ? 334 SER B CA  1 
ATOM 6993 C C   . SER D 4 334 ? 137.559 131.050 117.912 1.00 40.64  ? 334 SER B C   1 
ATOM 6994 O O   . SER D 4 334 ? 138.399 131.086 118.813 1.00 40.64  ? 334 SER B O   1 
ATOM 6995 C CB  . SER D 4 334 ? 137.217 133.512 118.315 1.00 40.64  ? 334 SER B CB  1 
ATOM 6996 O OG  . SER D 4 334 ? 138.603 133.569 118.597 1.00 40.64  ? 334 SER B OG  1 
ATOM 6997 N N   . PHE D 4 335 ? 137.189 129.913 117.328 1.00 35.87  ? 335 PHE B N   1 
ATOM 6998 C CA  . PHE D 4 335 ? 137.778 128.637 117.704 1.00 35.87  ? 335 PHE B CA  1 
ATOM 6999 C C   . PHE D 4 335 ? 137.844 127.730 116.485 1.00 35.87  ? 335 PHE B C   1 
ATOM 7000 O O   . PHE D 4 335 ? 137.067 127.879 115.539 1.00 35.87  ? 335 PHE B O   1 
ATOM 7001 C CB  . PHE D 4 335 ? 136.982 127.951 118.822 1.00 35.87  ? 335 PHE B CB  1 
ATOM 7002 C CG  . PHE D 4 335 ? 137.187 128.564 120.176 1.00 35.87  ? 335 PHE B CG  1 
ATOM 7003 C CD1 . PHE D 4 335 ? 138.445 128.597 120.753 1.00 35.87  ? 335 PHE B CD1 1 
ATOM 7004 C CD2 . PHE D 4 335 ? 136.121 129.105 120.875 1.00 35.87  ? 335 PHE B CD2 1 
ATOM 7005 C CE1 . PHE D 4 335 ? 138.636 129.161 121.998 1.00 35.87  ? 335 PHE B CE1 1 
ATOM 7006 C CE2 . PHE D 4 335 ? 136.306 129.670 122.121 1.00 35.87  ? 335 PHE B CE2 1 
ATOM 7007 C CZ  . PHE D 4 335 ? 137.565 129.698 122.684 1.00 35.87  ? 335 PHE B CZ  1 
ATOM 7008 N N   . LEU D 4 336 ? 138.782 126.786 116.520 1.00 30.96  ? 336 LEU B N   1 
ATOM 7009 C CA  . LEU D 4 336 ? 138.899 125.749 115.505 1.00 30.96  ? 336 LEU B CA  1 
ATOM 7010 C C   . LEU D 4 336 ? 138.747 124.389 116.169 1.00 30.96  ? 336 LEU B C   1 
ATOM 7011 O O   . LEU D 4 336 ? 139.280 124.162 117.258 1.00 30.96  ? 336 LEU B O   1 
ATOM 7012 C CB  . LEU D 4 336 ? 140.246 125.829 114.777 1.00 30.96  ? 336 LEU B CB  1 
ATOM 7013 C CG  . LEU D 4 336 ? 140.482 127.029 113.860 1.00 30.96  ? 336 LEU B CG  1 
ATOM 7014 C CD1 . LEU D 4 336 ? 141.949 127.123 113.478 1.00 30.96  ? 336 LEU B CD1 1 
ATOM 7015 C CD2 . LEU D 4 336 ? 139.617 126.930 112.617 1.00 30.96  ? 336 LEU B CD2 1 
ATOM 7016 N N   . LYS D 4 337 ? 138.021 123.482 115.520 1.00 31.77  ? 337 LYS B N   1 
ATOM 7017 C CA  . LYS D 4 337 ? 137.786 122.157 116.076 1.00 31.77  ? 337 LYS B CA  1 
ATOM 7018 C C   . LYS D 4 337 ? 138.183 121.093 115.065 1.00 31.77  ? 337 LYS B C   1 
ATOM 7019 O O   . LYS D 4 337 ? 137.724 121.120 113.919 1.00 31.77  ? 337 LYS B O   1 
ATOM 7020 C CB  . LYS D 4 337 ? 136.320 121.984 116.487 1.00 31.77  ? 337 LYS B CB  1 
ATOM 7021 C CG  . LYS D 4 337 ? 135.910 122.864 117.656 1.00 31.77  ? 337 LYS B CG  1 
ATOM 7022 C CD  . LYS D 4 337 ? 134.663 122.339 118.342 1.00 31.77  ? 337 LYS B CD  1 
ATOM 7023 C CE  . LYS D 4 337 ? 134.615 122.779 119.796 1.00 31.77  ? 337 LYS B CE  1 
ATOM 7024 N NZ  . LYS D 4 337 ? 133.818 124.023 119.973 1.00 31.77  ? 337 LYS B NZ  1 
ATOM 7025 N N   . ILE D 4 338 ? 139.030 120.161 115.494 1.00 32.46  ? 338 ILE B N   1 
ATOM 7026 C CA  . ILE D 4 338 ? 139.467 119.039 114.673 1.00 32.46  ? 338 ILE B CA  1 
ATOM 7027 C C   . ILE D 4 338 ? 138.732 117.798 115.156 1.00 32.46  ? 338 ILE B C   1 
ATOM 7028 O O   . ILE D 4 338 ? 138.923 117.360 116.300 1.00 32.46  ? 338 ILE B O   1 
ATOM 7029 C CB  . ILE D 4 338 ? 140.989 118.840 114.753 1.00 32.46  ? 338 ILE B CB  1 
ATOM 7030 C CG1 . ILE D 4 338 ? 141.719 120.183 114.690 1.00 32.46  ? 338 ILE B CG1 1 
ATOM 7031 C CG2 . ILE D 4 338 ? 141.462 117.916 113.640 1.00 32.46  ? 338 ILE B CG2 1 
ATOM 7032 C CD1 . ILE D 4 338 ? 141.651 120.857 113.349 1.00 32.46  ? 338 ILE B CD1 1 
ATOM 7033 N N   . TRP D 4 339 ? 137.911 117.229 114.276 1.00 34.83  ? 339 TRP B N   1 
ATOM 7034 C CA  . TRP D 4 339 ? 137.045 116.098 114.564 1.00 34.83  ? 339 TRP B CA  1 
ATOM 7035 C C   . TRP D 4 339 ? 137.606 114.852 113.895 1.00 34.83  ? 339 TRP B C   1 
ATOM 7036 O O   . TRP D 4 339 ? 138.033 114.898 112.734 1.00 34.83  ? 339 TRP B O   1 
ATOM 7037 C CB  . TRP D 4 339 ? 135.629 116.359 114.040 1.00 34.83  ? 339 TRP B CB  1 
ATOM 7038 C CG  . TRP D 4 339 ? 134.941 117.545 114.645 1.00 34.83  ? 339 TRP B CG  1 
ATOM 7039 C CD1 . TRP D 4 339 ? 135.050 118.844 114.242 1.00 34.83  ? 339 TRP B CD1 1 
ATOM 7040 C CD2 . TRP D 4 339 ? 133.988 117.536 115.713 1.00 34.83  ? 339 TRP B CD2 1 
ATOM 7041 N NE1 . TRP D 4 339 ? 134.253 119.649 115.017 1.00 34.83  ? 339 TRP B NE1 1 
ATOM 7042 C CE2 . TRP D 4 339 ? 133.587 118.870 115.926 1.00 34.83  ? 339 TRP B CE2 1 
ATOM 7043 C CE3 . TRP D 4 339 ? 133.445 116.533 116.520 1.00 34.83  ? 339 TRP B CE3 1 
ATOM 7044 C CZ2 . TRP D 4 339 ? 132.670 119.225 116.912 1.00 34.83  ? 339 TRP B CZ2 1 
ATOM 7045 C CZ3 . TRP D 4 339 ? 132.537 116.888 117.499 1.00 34.83  ? 339 TRP B CZ3 1 
ATOM 7046 C CH2 . TRP D 4 339 ? 132.157 118.221 117.685 1.00 34.83  ? 339 TRP B CH2 1 
ATOM 7047 N N   . ASN D 4 340 ? 137.595 113.742 114.624 1.00 42.73  ? 340 ASN B N   1 
ATOM 7048 C CA  . ASN D 4 340 ? 138.064 112.467 114.095 1.00 42.73  ? 340 ASN B CA  1 
ATOM 7049 C C   . ASN D 4 340 ? 137.298 111.318 114.745 1.00 42.73  ? 340 ASN B C   1 
ATOM 7050 O O   . ASN D 4 340 ? 137.091 111.304 115.958 1.00 42.73  ? 340 ASN B O   1 
ATOM 7051 C CB  . ASN D 4 340 ? 139.570 112.310 114.326 1.00 42.73  ? 340 ASN B CB  1 
ATOM 7052 C CG  . ASN D 4 340 ? 140.154 111.101 113.616 1.00 42.73  ? 340 ASN B CG  1 
ATOM 7053 O OD1 . ASN D 4 340 ? 141.357 110.846 113.676 1.00 42.73  ? 340 ASN B OD1 1 
ATOM 7054 N ND2 . ASN D 4 340 ? 139.296 110.346 112.941 1.00 42.73  ? 340 ASN B ND2 1 
ATOM 7055 O OXT . ASN D 4 340 ? 136.869 110.379 114.076 1.00 42.73  ? 340 ASN B OXT 1 
ATOM 7056 N N   . ALA E 5 12  ? 120.874 139.982 72.875  1.00 102.37 ? 12  ALA C N   1 
ATOM 7057 C CA  . ALA E 5 12  ? 121.151 138.778 73.648  1.00 102.37 ? 12  ALA C CA  1 
ATOM 7058 C C   . ALA E 5 12  ? 121.815 137.713 72.780  1.00 102.37 ? 12  ALA C C   1 
ATOM 7059 O O   . ALA E 5 12  ? 121.537 136.523 72.923  1.00 102.37 ? 12  ALA C O   1 
ATOM 7060 C CB  . ALA E 5 12  ? 119.871 138.237 74.266  1.00 102.37 ? 12  ALA C CB  1 
ATOM 7061 N N   . ARG E 5 13  ? 122.690 138.155 71.873  1.00 101.25 ? 13  ARG C N   1 
ATOM 7062 C CA  . ARG E 5 13  ? 123.392 137.217 71.003  1.00 101.25 ? 13  ARG C CA  1 
ATOM 7063 C C   . ARG E 5 13  ? 124.309 136.301 71.803  1.00 101.25 ? 13  ARG C C   1 
ATOM 7064 O O   . ARG E 5 13  ? 124.397 135.099 71.522  1.00 101.25 ? 13  ARG C O   1 
ATOM 7065 C CB  . ARG E 5 13  ? 124.185 137.979 69.942  1.00 101.25 ? 13  ARG C CB  1 
ATOM 7066 N N   . LYS E 5 14  ? 125.008 136.852 72.799  1.00 106.18 ? 14  LYS C N   1 
ATOM 7067 C CA  . LYS E 5 14  ? 125.882 136.032 73.632  1.00 106.18 ? 14  LYS C CA  1 
ATOM 7068 C C   . LYS E 5 14  ? 125.085 134.994 74.412  1.00 106.18 ? 14  LYS C C   1 
ATOM 7069 O O   . LYS E 5 14  ? 125.507 133.837 74.530  1.00 106.18 ? 14  LYS C O   1 
ATOM 7070 C CB  . LYS E 5 14  ? 126.684 136.920 74.583  1.00 106.18 ? 14  LYS C CB  1 
ATOM 7071 N N   . LEU E 5 15  ? 123.930 135.390 74.954  1.00 107.19 ? 15  LEU C N   1 
ATOM 7072 C CA  . LEU E 5 15  ? 123.084 134.440 75.670  1.00 107.19 ? 15  LEU C CA  1 
ATOM 7073 C C   . LEU E 5 15  ? 122.577 133.345 74.740  1.00 107.19 ? 15  LEU C C   1 
ATOM 7074 O O   . LEU E 5 15  ? 122.529 132.169 75.122  1.00 107.19 ? 15  LEU C O   1 
ATOM 7075 C CB  . LEU E 5 15  ? 121.915 135.172 76.328  1.00 107.19 ? 15  LEU C CB  1 
ATOM 7076 N N   . VAL E 5 16  ? 122.193 133.712 73.515  1.00 106.34 ? 16  VAL C N   1 
ATOM 7077 C CA  . VAL E 5 16  ? 121.727 132.722 72.548  1.00 106.34 ? 16  VAL C CA  1 
ATOM 7078 C C   . VAL E 5 16  ? 122.843 131.741 72.210  1.00 106.34 ? 16  VAL C C   1 
ATOM 7079 O O   . VAL E 5 16  ? 122.624 130.525 72.147  1.00 106.34 ? 16  VAL C O   1 
ATOM 7080 C CB  . VAL E 5 16  ? 121.186 133.423 71.287  1.00 106.34 ? 16  VAL C CB  1 
ATOM 7081 C CG1 . VAL E 5 16  ? 121.114 132.451 70.118  1.00 106.34 ? 16  VAL C CG1 1 
ATOM 7082 C CG2 . VAL E 5 16  ? 119.820 134.032 71.565  1.00 106.34 ? 16  VAL C CG2 1 
ATOM 7083 N N   . GLU E 5 17  ? 124.057 132.253 71.989  1.00 104.84 ? 17  GLU C N   1 
ATOM 7084 C CA  . GLU E 5 17  ? 125.186 131.380 71.682  1.00 104.84 ? 17  GLU C CA  1 
ATOM 7085 C C   . GLU E 5 17  ? 125.500 130.451 72.849  1.00 104.84 ? 17  GLU C C   1 
ATOM 7086 O O   . GLU E 5 17  ? 125.785 129.264 72.647  1.00 104.84 ? 17  GLU C O   1 
ATOM 7087 C CB  . GLU E 5 17  ? 126.412 132.217 71.317  1.00 104.84 ? 17  GLU C CB  1 
ATOM 7088 N N   . GLN E 5 18  ? 125.456 130.973 74.077  1.00 102.20 ? 18  GLN C N   1 
ATOM 7089 C CA  . GLN E 5 18  ? 125.715 130.137 75.246  1.00 102.20 ? 18  GLN C CA  1 
ATOM 7090 C C   . GLN E 5 18  ? 124.656 129.053 75.396  1.00 102.20 ? 18  GLN C C   1 
ATOM 7091 O O   . GLN E 5 18  ? 124.977 127.901 75.712  1.00 102.20 ? 18  GLN C O   1 
ATOM 7092 C CB  . GLN E 5 18  ? 125.783 131.002 76.505  1.00 102.20 ? 18  GLN C CB  1 
ATOM 7093 C CG  . GLN E 5 18  ? 126.149 130.238 77.768  1.00 102.20 ? 18  GLN C CG  1 
ATOM 7094 C CD  . GLN E 5 18  ? 127.448 129.467 77.632  1.00 102.20 ? 18  GLN C CD  1 
ATOM 7095 O OE1 . GLN E 5 18  ? 128.412 129.949 77.037  1.00 102.20 ? 18  GLN C OE1 1 
ATOM 7096 N NE2 . GLN E 5 18  ? 127.479 128.260 78.186  1.00 102.20 ? 18  GLN C NE2 1 
ATOM 7097 N N   . LEU E 5 19  ? 123.386 129.402 75.172  1.00 107.51 ? 19  LEU C N   1 
ATOM 7098 C CA  . LEU E 5 19  ? 122.320 128.408 75.253  1.00 107.51 ? 19  LEU C CA  1 
ATOM 7099 C C   . LEU E 5 19  ? 122.478 127.341 74.178  1.00 107.51 ? 19  LEU C C   1 
ATOM 7100 O O   . LEU E 5 19  ? 122.263 126.151 74.438  1.00 107.51 ? 19  LEU C O   1 
ATOM 7101 C CB  . LEU E 5 19  ? 120.957 129.091 75.137  1.00 107.51 ? 19  LEU C CB  1 
ATOM 7102 N N   . LYS E 5 20  ? 122.850 127.748 72.962  1.00 107.41 ? 20  LYS C N   1 
ATOM 7103 C CA  . LYS E 5 20  ? 123.064 126.780 71.891  1.00 107.41 ? 20  LYS C CA  1 
ATOM 7104 C C   . LYS E 5 20  ? 124.230 125.853 72.211  1.00 107.41 ? 20  LYS C C   1 
ATOM 7105 O O   . LYS E 5 20  ? 124.162 124.645 71.952  1.00 107.41 ? 20  LYS C O   1 
ATOM 7106 C CB  . LYS E 5 20  ? 123.302 127.506 70.567  1.00 107.41 ? 20  LYS C CB  1 
ATOM 7107 N N   . MET E 5 21  ? 125.313 126.401 72.767  1.00 110.88 ? 21  MET C N   1 
ATOM 7108 C CA  . MET E 5 21  ? 126.452 125.570 73.146  1.00 110.88 ? 21  MET C CA  1 
ATOM 7109 C C   . MET E 5 21  ? 126.079 124.595 74.256  1.00 110.88 ? 21  MET C C   1 
ATOM 7110 O O   . MET E 5 21  ? 126.488 123.428 74.230  1.00 110.88 ? 21  MET C O   1 
ATOM 7111 C CB  . MET E 5 21  ? 127.624 126.452 73.576  1.00 110.88 ? 21  MET C CB  1 
ATOM 7112 N N   . GLU E 5 22  ? 125.308 125.057 75.243  1.00 112.22 ? 22  GLU C N   1 
ATOM 7113 C CA  . GLU E 5 22  ? 124.886 124.178 76.329  1.00 112.22 ? 22  GLU C CA  1 
ATOM 7114 C C   . GLU E 5 22  ? 123.970 123.070 75.824  1.00 112.22 ? 22  GLU C C   1 
ATOM 7115 O O   . GLU E 5 22  ? 124.088 121.916 76.252  1.00 112.22 ? 22  GLU C O   1 
ATOM 7116 C CB  . GLU E 5 22  ? 124.193 124.990 77.423  1.00 112.22 ? 22  GLU C CB  1 
ATOM 7117 N N   . ALA E 5 23  ? 123.049 123.400 74.914  1.00 116.77 ? 23  ALA C N   1 
ATOM 7118 C CA  . ALA E 5 23  ? 122.136 122.392 74.387  1.00 116.77 ? 23  ALA C CA  1 
ATOM 7119 C C   . ALA E 5 23  ? 122.857 121.383 73.502  1.00 116.77 ? 23  ALA C C   1 
ATOM 7120 O O   . ALA E 5 23  ? 122.393 120.246 73.358  1.00 116.77 ? 23  ALA C O   1 
ATOM 7121 C CB  . ALA E 5 23  ? 121.003 123.063 73.612  1.00 116.77 ? 23  ALA C CB  1 
ATOM 7122 N N   . ASN E 5 24  ? 123.983 121.774 72.905  1.00 118.28 ? 24  ASN C N   1 
ATOM 7123 C CA  . ASN E 5 24  ? 124.740 120.876 72.043  1.00 118.28 ? 24  ASN C CA  1 
ATOM 7124 C C   . ASN E 5 24  ? 125.644 119.927 72.818  1.00 118.28 ? 24  ASN C C   1 
ATOM 7125 O O   . ASN E 5 24  ? 126.253 119.042 72.207  1.00 118.28 ? 24  ASN C O   1 
ATOM 7126 C CB  . ASN E 5 24  ? 125.580 121.685 71.050  1.00 118.28 ? 24  ASN C CB  1 
ATOM 7127 N N   . ILE E 5 25  ? 125.746 120.085 74.134  1.00 118.99 ? 25  ILE C N   1 
ATOM 7128 C CA  . ILE E 5 25  ? 126.591 119.216 74.946  1.00 118.99 ? 25  ILE C CA  1 
ATOM 7129 C C   . ILE E 5 25  ? 125.885 117.883 75.148  1.00 118.99 ? 25  ILE C C   1 
ATOM 7130 O O   . ILE E 5 25  ? 124.716 117.839 75.550  1.00 118.99 ? 25  ILE C O   1 
ATOM 7131 C CB  . ILE E 5 25  ? 126.921 119.881 76.292  1.00 118.99 ? 25  ILE C CB  1 
ATOM 7132 N N   . ASP E 5 26  ? 126.592 116.793 74.866  1.00 113.21 ? 26  ASP C N   1 
ATOM 7133 C CA  . ASP E 5 26  ? 126.018 115.464 75.027  1.00 113.21 ? 26  ASP C CA  1 
ATOM 7134 C C   . ASP E 5 26  ? 125.794 115.153 76.501  1.00 113.21 ? 26  ASP C C   1 
ATOM 7135 O O   . ASP E 5 26  ? 126.599 115.520 77.362  1.00 113.21 ? 26  ASP C O   1 
ATOM 7136 C CB  . ASP E 5 26  ? 126.931 114.411 74.399  1.00 113.21 ? 26  ASP C CB  1 
ATOM 7137 N N   . ARG E 5 27  ? 124.689 114.469 76.789  1.00 107.11 ? 27  ARG C N   1 
ATOM 7138 C CA  . ARG E 5 27  ? 124.326 114.103 78.149  1.00 107.11 ? 27  ARG C CA  1 
ATOM 7139 C C   . ARG E 5 27  ? 124.097 112.602 78.232  1.00 107.11 ? 27  ARG C C   1 
ATOM 7140 O O   . ARG E 5 27  ? 123.632 111.973 77.277  1.00 107.11 ? 27  ARG C O   1 
ATOM 7141 C CB  . ARG E 5 27  ? 123.067 114.849 78.615  1.00 107.11 ? 27  ARG C CB  1 
ATOM 7142 C CG  . ARG E 5 27  ? 123.241 116.354 78.725  1.00 107.11 ? 27  ARG C CG  1 
ATOM 7143 C CD  . ARG E 5 27  ? 121.951 117.027 79.165  1.00 107.11 ? 27  ARG C CD  1 
ATOM 7144 N NE  . ARG E 5 27  ? 122.090 118.476 79.250  1.00 107.11 ? 27  ARG C NE  1 
ATOM 7145 C CZ  . ARG E 5 27  ? 121.836 119.312 78.254  1.00 107.11 ? 27  ARG C CZ  1 
ATOM 7146 N NH1 . ARG E 5 27  ? 121.424 118.878 77.074  1.00 107.11 ? 27  ARG C NH1 1 
ATOM 7147 N NH2 . ARG E 5 27  ? 121.998 120.618 78.446  1.00 107.11 ? 27  ARG C NH2 1 
ATOM 7148 N N   . ILE E 5 28  ? 124.428 112.033 79.387  1.00 102.44 ? 28  ILE C N   1 
ATOM 7149 C CA  . ILE E 5 28  ? 124.254 110.611 79.633  1.00 102.44 ? 28  ILE C CA  1 
ATOM 7150 C C   . ILE E 5 28  ? 123.076 110.414 80.583  1.00 102.44 ? 28  ILE C C   1 
ATOM 7151 O O   . ILE E 5 28  ? 122.538 111.364 81.153  1.00 102.44 ? 28  ILE C O   1 
ATOM 7152 C CB  . ILE E 5 28  ? 125.533 109.957 80.192  1.00 102.44 ? 28  ILE C CB  1 
ATOM 7153 C CG1 . ILE E 5 28  ? 125.814 110.457 81.610  1.00 102.44 ? 28  ILE C CG1 1 
ATOM 7154 C CG2 . ILE E 5 28  ? 126.717 110.237 79.278  1.00 102.44 ? 28  ILE C CG2 1 
ATOM 7155 C CD1 . ILE E 5 28  ? 126.846 109.636 82.352  1.00 102.44 ? 28  ILE C CD1 1 
ATOM 7156 N N   . LYS E 5 29  ? 122.674 109.157 80.746  1.00 103.11 ? 29  LYS C N   1 
ATOM 7157 C CA  . LYS E 5 29  ? 121.554 108.831 81.615  1.00 103.11 ? 29  LYS C CA  1 
ATOM 7158 C C   . LYS E 5 29  ? 121.902 109.101 83.075  1.00 103.11 ? 29  LYS C C   1 
ATOM 7159 O O   . LYS E 5 29  ? 123.052 108.965 83.503  1.00 103.11 ? 29  LYS C O   1 
ATOM 7160 C CB  . LYS E 5 29  ? 121.149 107.368 81.437  1.00 103.11 ? 29  LYS C CB  1 
ATOM 7161 N N   . VAL E 5 30  ? 120.883 109.496 83.842  1.00 99.20  ? 30  VAL C N   1 
ATOM 7162 C CA  . VAL E 5 30  ? 121.069 109.740 85.271  1.00 99.20  ? 30  VAL C CA  1 
ATOM 7163 C C   . VAL E 5 30  ? 121.424 108.444 85.989  1.00 99.20  ? 30  VAL C C   1 
ATOM 7164 O O   . VAL E 5 30  ? 122.220 108.437 86.938  1.00 99.20  ? 30  VAL C O   1 
ATOM 7165 C CB  . VAL E 5 30  ? 119.807 110.395 85.863  1.00 99.20  ? 30  VAL C CB  1 
ATOM 7166 C CG1 . VAL E 5 30  ? 119.938 110.560 87.368  1.00 99.20  ? 30  VAL C CG1 1 
ATOM 7167 C CG2 . VAL E 5 30  ? 119.547 111.737 85.197  1.00 99.20  ? 30  VAL C CG2 1 
ATOM 7168 N N   . SER E 5 31  ? 120.844 107.327 85.544  1.00 98.94  ? 31  SER C N   1 
ATOM 7169 C CA  . SER E 5 31  ? 121.133 106.039 86.166  1.00 98.94  ? 31  SER C CA  1 
ATOM 7170 C C   . SER E 5 31  ? 122.602 105.668 86.012  1.00 98.94  ? 31  SER C C   1 
ATOM 7171 O O   . SER E 5 31  ? 123.209 105.116 86.936  1.00 98.94  ? 31  SER C O   1 
ATOM 7172 C CB  . SER E 5 31  ? 120.239 104.954 85.565  1.00 98.94  ? 31  SER C CB  1 
ATOM 7173 O OG  . SER E 5 31  ? 118.927 105.023 86.097  1.00 98.94  ? 31  SER C OG  1 
ATOM 7174 N N   . LYS E 5 32  ? 123.190 105.955 84.848  1.00 95.53  ? 32  LYS C N   1 
ATOM 7175 C CA  . LYS E 5 32  ? 124.607 105.666 84.644  1.00 95.53  ? 32  LYS C CA  1 
ATOM 7176 C C   . LYS E 5 32  ? 125.481 106.478 85.592  1.00 95.53  ? 32  LYS C C   1 
ATOM 7177 O O   . LYS E 5 32  ? 126.442 105.953 86.168  1.00 95.53  ? 32  LYS C O   1 
ATOM 7178 C CB  . LYS E 5 32  ? 124.994 105.938 83.190  1.00 95.53  ? 32  LYS C CB  1 
ATOM 7179 N N   . ALA E 5 33  ? 125.164 107.764 85.768  1.00 90.40  ? 33  ALA C N   1 
ATOM 7180 C CA  . ALA E 5 33  ? 125.931 108.597 86.689  1.00 90.40  ? 33  ALA C CA  1 
ATOM 7181 C C   . ALA E 5 33  ? 125.787 108.108 88.125  1.00 90.40  ? 33  ALA C C   1 
ATOM 7182 O O   . ALA E 5 33  ? 126.766 108.079 88.882  1.00 90.40  ? 33  ALA C O   1 
ATOM 7183 C CB  . ALA E 5 33  ? 125.490 110.055 86.570  1.00 90.40  ? 33  ALA C CB  1 
ATOM 7184 N N   . ALA E 5 34  ? 124.570 107.721 88.518  1.00 88.86  ? 34  ALA C N   1 
ATOM 7185 C CA  . ALA E 5 34  ? 124.363 107.190 89.862  1.00 88.86  ? 34  ALA C CA  1 
ATOM 7186 C C   . ALA E 5 34  ? 125.145 105.899 90.071  1.00 88.86  ? 34  ALA C C   1 
ATOM 7187 O O   . ALA E 5 34  ? 125.743 105.690 91.133  1.00 88.86  ? 34  ALA C O   1 
ATOM 7188 C CB  . ALA E 5 34  ? 122.872 106.964 90.110  1.00 88.86  ? 34  ALA C CB  1 
ATOM 7189 N N   . ALA E 5 35  ? 125.149 105.020 89.066  1.00 85.57  ? 35  ALA C N   1 
ATOM 7190 C CA  . ALA E 5 35  ? 125.904 103.776 89.169  1.00 85.57  ? 35  ALA C CA  1 
ATOM 7191 C C   . ALA E 5 35  ? 127.399 104.046 89.269  1.00 85.57  ? 35  ALA C C   1 
ATOM 7192 O O   . ALA E 5 35  ? 128.105 103.381 90.035  1.00 85.57  ? 35  ALA C O   1 
ATOM 7193 C CB  . ALA E 5 35  ? 125.598 102.876 87.972  1.00 85.57  ? 35  ALA C CB  1 
ATOM 7194 N N   . ASP E 5 36  ? 127.902 105.015 88.500  1.00 79.21  ? 36  ASP C N   1 
ATOM 7195 C CA  . ASP E 5 36  ? 129.316 105.367 88.586  1.00 79.21  ? 36  ASP C CA  1 
ATOM 7196 C C   . ASP E 5 36  ? 129.667 105.917 89.964  1.00 79.21  ? 36  ASP C C   1 
ATOM 7197 O O   . ASP E 5 36  ? 130.710 105.571 90.535  1.00 79.21  ? 36  ASP C O   1 
ATOM 7198 C CB  . ASP E 5 36  ? 129.673 106.378 87.497  1.00 79.21  ? 36  ASP C CB  1 
ATOM 7199 N N   . LEU E 5 37  ? 128.807 106.778 90.514  1.00 74.10  ? 37  LEU C N   1 
ATOM 7200 C CA  . LEU E 5 37  ? 129.057 107.319 91.847  1.00 74.10  ? 37  LEU C CA  1 
ATOM 7201 C C   . LEU E 5 37  ? 129.042 106.220 92.902  1.00 74.10  ? 37  LEU C C   1 
ATOM 7202 O O   . LEU E 5 37  ? 129.875 106.216 93.815  1.00 74.10  ? 37  LEU C O   1 
ATOM 7203 C CB  . LEU E 5 37  ? 128.030 108.401 92.180  1.00 74.10  ? 37  LEU C CB  1 
ATOM 7204 C CG  . LEU E 5 37  ? 128.183 109.721 91.422  1.00 74.10  ? 37  LEU C CG  1 
ATOM 7205 C CD1 . LEU E 5 37  ? 127.092 110.697 91.822  1.00 74.10  ? 37  LEU C CD1 1 
ATOM 7206 C CD2 . LEU E 5 37  ? 129.559 110.321 91.665  1.00 74.10  ? 37  LEU C CD2 1 
ATOM 7207 N N   . MET E 5 38  ? 128.100 105.280 92.797  1.00 75.23  ? 38  MET C N   1 
ATOM 7208 C CA  . MET E 5 38  ? 128.063 104.159 93.734  1.00 75.23  ? 38  MET C CA  1 
ATOM 7209 C C   . MET E 5 38  ? 129.313 103.295 93.603  1.00 75.23  ? 38  MET C C   1 
ATOM 7210 O O   . MET E 5 38  ? 129.883 102.844 94.606  1.00 75.23  ? 38  MET C O   1 
ATOM 7211 C CB  . MET E 5 38  ? 126.802 103.326 93.503  1.00 75.23  ? 38  MET C CB  1 
ATOM 7212 C CG  . MET E 5 38  ? 125.577 103.836 94.244  1.00 75.23  ? 38  MET C CG  1 
ATOM 7213 S SD  . MET E 5 38  ? 124.211 102.658 94.243  1.00 75.23  ? 38  MET C SD  1 
ATOM 7214 C CE  . MET E 5 38  ? 125.099 101.103 94.263  1.00 75.23  ? 38  MET C CE  1 
ATOM 7215 N N   . ALA E 5 39  ? 129.747 103.040 92.367  1.00 70.13  ? 39  ALA C N   1 
ATOM 7216 C CA  . ALA E 5 39  ? 130.961 102.262 92.158  1.00 70.13  ? 39  ALA C CA  1 
ATOM 7217 C C   . ALA E 5 39  ? 132.154 102.942 92.810  1.00 70.13  ? 39  ALA C C   1 
ATOM 7218 O O   . ALA E 5 39  ? 132.951 102.292 93.492  1.00 70.13  ? 39  ALA C O   1 
ATOM 7219 C CB  . ALA E 5 39  ? 131.205 102.057 90.663  1.00 70.13  ? 39  ALA C CB  1 
ATOM 7220 N N   . TYR E 5 40  ? 132.270 104.261 92.642  1.00 61.44  ? 40  TYR C N   1 
ATOM 7221 C CA  . TYR E 5 40  ? 133.354 104.996 93.289  1.00 61.44  ? 40  TYR C CA  1 
ATOM 7222 C C   . TYR E 5 40  ? 133.248 104.918 94.808  1.00 61.44  ? 40  TYR C C   1 
ATOM 7223 O O   . TYR E 5 40  ? 134.258 104.740 95.502  1.00 61.44  ? 40  TYR C O   1 
ATOM 7224 C CB  . TYR E 5 40  ? 133.347 106.452 92.824  1.00 61.44  ? 40  TYR C CB  1 
ATOM 7225 C CG  . TYR E 5 40  ? 134.546 107.251 93.282  1.00 61.44  ? 40  TYR C CG  1 
ATOM 7226 C CD1 . TYR E 5 40  ? 135.723 107.257 92.545  1.00 61.44  ? 40  TYR C CD1 1 
ATOM 7227 C CD2 . TYR E 5 40  ? 134.500 108.002 94.450  1.00 61.44  ? 40  TYR C CD2 1 
ATOM 7228 C CE1 . TYR E 5 40  ? 136.821 107.987 92.959  1.00 61.44  ? 40  TYR C CE1 1 
ATOM 7229 C CE2 . TYR E 5 40  ? 135.593 108.733 94.872  1.00 61.44  ? 40  TYR C CE2 1 
ATOM 7230 C CZ  . TYR E 5 40  ? 136.751 108.722 94.123  1.00 61.44  ? 40  TYR C CZ  1 
ATOM 7231 O OH  . TYR E 5 40  ? 137.842 109.449 94.538  1.00 61.44  ? 40  TYR C OH  1 
ATOM 7232 N N   . CYS E 5 41  ? 132.031 105.048 95.343  1.00 65.84  ? 41  CYS C N   1 
ATOM 7233 C CA  . CYS E 5 41  ? 131.848 105.064 96.792  1.00 65.84  ? 41  CYS C CA  1 
ATOM 7234 C C   . CYS E 5 41  ? 132.260 103.739 97.420  1.00 65.84  ? 41  CYS C C   1 
ATOM 7235 O O   . CYS E 5 41  ? 133.054 103.710 98.367  1.00 65.84  ? 41  CYS C O   1 
ATOM 7236 C CB  . CYS E 5 41  ? 130.395 105.395 97.132  1.00 65.84  ? 41  CYS C CB  1 
ATOM 7237 S SG  . CYS E 5 41  ? 130.025 107.163 97.147  1.00 65.84  ? 41  CYS C SG  1 
ATOM 7238 N N   . GLU E 5 42  ? 131.733 102.624 96.906  1.00 69.34  ? 42  GLU C N   1 
ATOM 7239 C CA  . GLU E 5 42  ? 132.146 101.329 97.444  1.00 69.34  ? 42  GLU C CA  1 
ATOM 7240 C C   . GLU E 5 42  ? 133.529 100.894 96.970  1.00 69.34  ? 42  GLU C C   1 
ATOM 7241 O O   . GLU E 5 42  ? 134.055 99.902  97.485  1.00 69.34  ? 42  GLU C O   1 
ATOM 7242 C CB  . GLU E 5 42  ? 131.111 100.239 97.139  1.00 69.34  ? 42  GLU C CB  1 
ATOM 7243 C CG  . GLU E 5 42  ? 129.914 100.211 98.102  1.00 69.34  ? 42  GLU C CG  1 
ATOM 7244 C CD  . GLU E 5 42  ? 128.762 101.113 97.711  1.00 69.34  ? 42  GLU C CD  1 
ATOM 7245 O OE1 . GLU E 5 42  ? 128.804 101.707 96.621  1.00 69.34  ? 42  GLU C OE1 1 
ATOM 7246 O OE2 . GLU E 5 42  ? 127.805 101.226 98.505  1.00 69.34  ? 42  GLU C OE2 1 
ATOM 7247 N N   . ALA E 5 43  ? 134.134 101.599 96.011  1.00 65.18  ? 43  ALA C N   1 
ATOM 7248 C CA  . ALA E 5 43  ? 135.534 101.347 95.698  1.00 65.18  ? 43  ALA C CA  1 
ATOM 7249 C C   . ALA E 5 43  ? 136.470 102.019 96.693  1.00 65.18  ? 43  ALA C C   1 
ATOM 7250 O O   . ALA E 5 43  ? 137.522 101.461 97.022  1.00 65.18  ? 43  ALA C O   1 
ATOM 7251 C CB  . ALA E 5 43  ? 135.851 101.818 94.278  1.00 65.18  ? 43  ALA C CB  1 
ATOM 7252 N N   . HIS E 5 44  ? 136.109 103.207 97.179  1.00 61.93  ? 44  HIS C N   1 
ATOM 7253 C CA  . HIS E 5 44  ? 136.939 103.944 98.125  1.00 61.93  ? 44  HIS C CA  1 
ATOM 7254 C C   . HIS E 5 44  ? 136.388 103.911 99.546  1.00 61.93  ? 44  HIS C C   1 
ATOM 7255 O O   . HIS E 5 44  ? 136.869 104.664 100.401 1.00 61.93  ? 44  HIS C O   1 
ATOM 7256 C CB  . HIS E 5 44  ? 137.109 105.394 97.664  1.00 61.93  ? 44  HIS C CB  1 
ATOM 7257 C CG  . HIS E 5 44  ? 137.984 105.545 96.459  1.00 61.93  ? 44  HIS C CG  1 
ATOM 7258 N ND1 . HIS E 5 44  ? 137.591 105.146 95.200  1.00 61.93  ? 44  HIS C ND1 1 
ATOM 7259 C CD2 . HIS E 5 44  ? 139.232 106.050 96.321  1.00 61.93  ? 44  HIS C CD2 1 
ATOM 7260 C CE1 . HIS E 5 44  ? 138.560 105.399 94.338  1.00 61.93  ? 44  HIS C CE1 1 
ATOM 7261 N NE2 . HIS E 5 44  ? 139.567 105.948 94.993  1.00 61.93  ? 44  HIS C NE2 1 
ATOM 7262 N N   . ALA E 5 45  ? 135.394 103.063 99.821  1.00 63.21  ? 45  ALA C N   1 
ATOM 7263 C CA  . ALA E 5 45  ? 134.811 103.009 101.159 1.00 63.21  ? 45  ALA C CA  1 
ATOM 7264 C C   . ALA E 5 45  ? 135.825 102.533 102.193 1.00 63.21  ? 45  ALA C C   1 
ATOM 7265 O O   . ALA E 5 45  ? 135.875 103.062 103.309 1.00 63.21  ? 45  ALA C O   1 
ATOM 7266 C CB  . ALA E 5 45  ? 133.580 102.104 101.160 1.00 63.21  ? 45  ALA C CB  1 
ATOM 7267 N N   . LYS E 5 46  ? 136.637 101.533 101.843 1.00 63.99  ? 46  LYS C N   1 
ATOM 7268 C CA  . LYS E 5 46  ? 137.609 101.000 102.793 1.00 63.99  ? 46  LYS C CA  1 
ATOM 7269 C C   . LYS E 5 46  ? 138.705 102.008 103.111 1.00 63.99  ? 46  LYS C C   1 
ATOM 7270 O O   . LYS E 5 46  ? 139.323 101.932 104.180 1.00 63.99  ? 46  LYS C O   1 
ATOM 7271 C CB  . LYS E 5 46  ? 138.219 99.708  102.250 1.00 63.99  ? 46  LYS C CB  1 
ATOM 7272 N N   . GLU E 5 47  ? 138.962 102.952 102.209 1.00 62.41  ? 47  GLU C N   1 
ATOM 7273 C CA  . GLU E 5 47  ? 140.014 103.942 102.396 1.00 62.41  ? 47  GLU C CA  1 
ATOM 7274 C C   . GLU E 5 47  ? 139.525 105.215 103.073 1.00 62.41  ? 47  GLU C C   1 
ATOM 7275 O O   . GLU E 5 47  ? 140.314 106.151 103.239 1.00 62.41  ? 47  GLU C O   1 
ATOM 7276 C CB  . GLU E 5 47  ? 140.654 104.291 101.048 1.00 62.41  ? 47  GLU C CB  1 
ATOM 7277 N N   . ASP E 5 48  ? 138.251 105.278 103.465 1.00 60.96  ? 48  ASP C N   1 
ATOM 7278 C CA  . ASP E 5 48  ? 137.706 106.469 104.101 1.00 60.96  ? 48  ASP C CA  1 
ATOM 7279 C C   . ASP E 5 48  ? 137.818 106.329 105.613 1.00 60.96  ? 48  ASP C C   1 
ATOM 7280 O O   . ASP E 5 48  ? 137.151 105.459 106.193 1.00 60.96  ? 48  ASP C O   1 
ATOM 7281 C CB  . ASP E 5 48  ? 136.254 106.677 103.692 1.00 60.96  ? 48  ASP C CB  1 
ATOM 7282 N N   . PRO E 5 49  ? 138.632 107.144 106.288 1.00 56.85  ? 49  PRO C N   1 
ATOM 7283 C CA  . PRO E 5 49  ? 138.749 107.029 107.748 1.00 56.85  ? 49  PRO C CA  1 
ATOM 7284 C C   . PRO E 5 49  ? 137.518 107.542 108.479 1.00 56.85  ? 49  PRO C C   1 
ATOM 7285 O O   . PRO E 5 49  ? 137.207 107.078 109.581 1.00 56.85  ? 49  PRO C O   1 
ATOM 7286 C CB  . PRO E 5 49  ? 139.987 107.877 108.073 1.00 56.85  ? 49  PRO C CB  1 
ATOM 7287 C CG  . PRO E 5 49  ? 140.666 108.126 106.749 1.00 56.85  ? 49  PRO C CG  1 
ATOM 7288 C CD  . PRO E 5 49  ? 139.574 108.127 105.736 1.00 56.85  ? 49  PRO C CD  1 
ATOM 7289 N N   . LEU E 5 50  ? 136.812 108.504 107.881 1.00 50.12  ? 50  LEU C N   1 
ATOM 7290 C CA  . LEU E 5 50  ? 135.610 109.038 108.511 1.00 50.12  ? 50  LEU C CA  1 
ATOM 7291 C C   . LEU E 5 50  ? 134.435 108.075 108.425 1.00 50.12  ? 50  LEU C C   1 
ATOM 7292 O O   . LEU E 5 50  ? 133.485 108.206 109.203 1.00 50.12  ? 50  LEU C O   1 
ATOM 7293 C CB  . LEU E 5 50  ? 135.230 110.378 107.879 1.00 50.12  ? 50  LEU C CB  1 
ATOM 7294 C CG  . LEU E 5 50  ? 136.205 111.537 108.095 1.00 50.12  ? 50  LEU C CG  1 
ATOM 7295 C CD1 . LEU E 5 50  ? 135.577 112.855 107.667 1.00 50.12  ? 50  LEU C CD1 1 
ATOM 7296 C CD2 . LEU E 5 50  ? 136.654 111.601 109.546 1.00 50.12  ? 50  LEU C CD2 1 
ATOM 7297 N N   . LEU E 5 51  ? 134.477 107.114 107.503 1.00 62.33  ? 51  LEU C N   1 
ATOM 7298 C CA  . LEU E 5 51  ? 133.410 106.126 107.372 1.00 62.33  ? 51  LEU C CA  1 
ATOM 7299 C C   . LEU E 5 51  ? 133.697 104.892 108.224 1.00 62.33  ? 51  LEU C C   1 
ATOM 7300 O O   . LEU E 5 51  ? 132.893 104.523 109.086 1.00 62.33  ? 51  LEU C O   1 
ATOM 7301 C CB  . LEU E 5 51  ? 133.231 105.743 105.898 1.00 62.33  ? 51  LEU C CB  1 
ATOM 7302 C CG  . LEU E 5 51  ? 132.104 104.761 105.580 1.00 62.33  ? 51  LEU C CG  1 
ATOM 7303 C CD1 . LEU E 5 51  ? 130.758 105.361 105.951 1.00 62.33  ? 51  LEU C CD1 1 
ATOM 7304 C CD2 . LEU E 5 51  ? 132.133 104.370 104.111 1.00 62.33  ? 51  LEU C CD2 1 
ATOM 7305 N N   . THR E 5 52  ? 134.839 104.249 107.992 1.00 72.30  ? 52  THR C N   1 
ATOM 7306 C CA  . THR E 5 52  ? 135.254 103.109 108.798 1.00 72.30  ? 52  THR C CA  1 
ATOM 7307 C C   . THR E 5 52  ? 136.122 103.594 109.950 1.00 72.30  ? 52  THR C C   1 
ATOM 7308 O O   . THR E 5 52  ? 137.136 104.262 109.704 1.00 72.30  ? 52  THR C O   1 
ATOM 7309 C CB  . THR E 5 52  ? 136.024 102.104 107.957 1.00 72.30  ? 52  THR C CB  1 
ATOM 7310 O OG1 . THR E 5 52  ? 137.210 102.720 107.440 1.00 72.30  ? 52  THR C OG1 1 
ATOM 7311 C CG2 . THR E 5 52  ? 135.168 101.615 106.797 1.00 72.30  ? 52  THR C CG2 1 
ATOM 7312 N N   . PRO E 5 53  ? 135.767 103.304 111.202 1.00 84.30  ? 53  PRO C N   1 
ATOM 7313 C CA  . PRO E 5 53  ? 136.570 103.794 112.330 1.00 84.30  ? 53  PRO C CA  1 
ATOM 7314 C C   . PRO E 5 53  ? 138.004 103.288 112.262 1.00 84.30  ? 53  PRO C C   1 
ATOM 7315 O O   . PRO E 5 53  ? 138.264 102.144 111.886 1.00 84.30  ? 53  PRO C O   1 
ATOM 7316 C CB  . PRO E 5 53  ? 135.835 103.241 113.556 1.00 84.30  ? 53  PRO C CB  1 
ATOM 7317 C CG  . PRO E 5 53  ? 134.444 102.966 113.080 1.00 84.30  ? 53  PRO C CG  1 
ATOM 7318 C CD  . PRO E 5 53  ? 134.582 102.553 111.647 1.00 84.30  ? 53  PRO C CD  1 
ATOM 7319 N N   . VAL E 5 54  ? 138.936 104.160 112.634 1.00 87.90  ? 54  VAL C N   1 
ATOM 7320 C CA  . VAL E 5 54  ? 140.362 103.849 112.583 1.00 87.90  ? 54  VAL C CA  1 
ATOM 7321 C C   . VAL E 5 54  ? 140.874 103.617 114.002 1.00 87.90  ? 54  VAL C C   1 
ATOM 7322 O O   . VAL E 5 54  ? 140.503 104.357 114.925 1.00 87.90  ? 54  VAL C O   1 
ATOM 7323 C CB  . VAL E 5 54  ? 141.144 104.963 111.861 1.00 87.90  ? 54  VAL C CB  1 
ATOM 7324 C CG1 . VAL E 5 54  ? 141.038 106.286 112.612 1.00 87.90  ? 54  VAL C CG1 1 
ATOM 7325 C CG2 . VAL E 5 54  ? 142.601 104.568 111.669 1.00 87.90  ? 54  VAL C CG2 1 
ATOM 7326 N N   . PRO E 5 55  ? 141.688 102.590 114.232 1.00 89.52  ? 55  PRO C N   1 
ATOM 7327 C CA  . PRO E 5 55  ? 142.262 102.390 115.566 1.00 89.52  ? 55  PRO C CA  1 
ATOM 7328 C C   . PRO E 5 55  ? 143.265 103.481 115.912 1.00 89.52  ? 55  PRO C C   1 
ATOM 7329 O O   . PRO E 5 55  ? 143.857 104.126 115.045 1.00 89.52  ? 55  PRO C O   1 
ATOM 7330 C CB  . PRO E 5 55  ? 142.944 101.019 115.471 1.00 89.52  ? 55  PRO C CB  1 
ATOM 7331 C CG  . PRO E 5 55  ? 142.401 100.382 114.231 1.00 89.52  ? 55  PRO C CG  1 
ATOM 7332 C CD  . PRO E 5 55  ? 142.022 101.493 113.310 1.00 89.52  ? 55  PRO C CD  1 
ATOM 7333 N N   . ALA E 5 56  ? 143.449 103.678 117.219 1.00 89.80  ? 56  ALA C N   1 
ATOM 7334 C CA  . ALA E 5 56  ? 144.347 104.713 117.716 1.00 89.80  ? 56  ALA C CA  1 
ATOM 7335 C C   . ALA E 5 56  ? 145.818 104.376 117.510 1.00 89.80  ? 56  ALA C C   1 
ATOM 7336 O O   . ALA E 5 56  ? 146.668 105.242 117.745 1.00 89.80  ? 56  ALA C O   1 
ATOM 7337 C CB  . ALA E 5 56  ? 144.082 104.967 119.201 1.00 89.80  ? 56  ALA C CB  1 
ATOM 7338 N N   . SER E 5 57  ? 146.138 103.149 117.090 1.00 89.48  ? 57  SER C N   1 
ATOM 7339 C CA  . SER E 5 57  ? 147.535 102.777 116.888 1.00 89.48  ? 57  SER C CA  1 
ATOM 7340 C C   . SER E 5 57  ? 148.182 103.617 115.794 1.00 89.48  ? 57  SER C C   1 
ATOM 7341 O O   . SER E 5 57  ? 149.327 104.061 115.937 1.00 89.48  ? 57  SER C O   1 
ATOM 7342 C CB  . SER E 5 57  ? 147.638 101.289 116.554 1.00 89.48  ? 57  SER C CB  1 
ATOM 7343 O OG  . SER E 5 57  ? 147.026 101.002 115.308 1.00 89.48  ? 57  SER C OG  1 
ATOM 7344 N N   . GLU E 5 58  ? 147.466 103.847 114.693 1.00 83.33  ? 58  GLU C N   1 
ATOM 7345 C CA  . GLU E 5 58  ? 147.970 104.646 113.582 1.00 83.33  ? 58  GLU C CA  1 
ATOM 7346 C C   . GLU E 5 58  ? 147.218 105.965 113.429 1.00 83.33  ? 58  GLU C C   1 
ATOM 7347 O O   . GLU E 5 58  ? 147.351 106.635 112.400 1.00 83.33  ? 58  GLU C O   1 
ATOM 7348 C CB  . GLU E 5 58  ? 147.910 103.842 112.282 1.00 83.33  ? 58  GLU C CB  1 
ATOM 7349 C CG  . GLU E 5 58  ? 146.509 103.657 111.711 1.00 83.33  ? 58  GLU C CG  1 
ATOM 7350 C CD  . GLU E 5 58  ? 145.775 102.472 112.312 1.00 83.33  ? 58  GLU C CD  1 
ATOM 7351 O OE1 . GLU E 5 58  ? 146.163 102.017 113.408 1.00 83.33  ? 58  GLU C OE1 1 
ATOM 7352 O OE2 . GLU E 5 58  ? 144.809 101.994 111.683 1.00 83.33  ? 58  GLU C OE2 1 
ATOM 7353 N N   . ASN E 5 59  ? 146.440 106.357 114.438 1.00 65.93  ? 59  ASN C N   1 
ATOM 7354 C CA  . ASN E 5 59  ? 145.672 107.593 114.378 1.00 65.93  ? 59  ASN C CA  1 
ATOM 7355 C C   . ASN E 5 59  ? 146.488 108.718 115.000 1.00 65.93  ? 59  ASN C C   1 
ATOM 7356 O O   . ASN E 5 59  ? 146.752 108.678 116.212 1.00 65.93  ? 59  ASN C O   1 
ATOM 7357 C CB  . ASN E 5 59  ? 144.345 107.433 115.105 1.00 65.93  ? 59  ASN C CB  1 
ATOM 7358 C CG  . ASN E 5 59  ? 143.380 108.567 114.818 1.00 65.93  ? 59  ASN C CG  1 
ATOM 7359 O OD1 . ASN E 5 59  ? 143.686 109.482 114.054 1.00 65.93  ? 59  ASN C OD1 1 
ATOM 7360 N ND2 . ASN E 5 59  ? 142.205 108.512 115.434 1.00 65.93  ? 59  ASN C ND2 1 
ATOM 7361 N N   . PRO E 5 60  ? 146.908 109.727 114.232 1.00 51.67  ? 60  PRO C N   1 
ATOM 7362 C CA  . PRO E 5 60  ? 147.651 110.846 114.834 1.00 51.67  ? 60  PRO C CA  1 
ATOM 7363 C C   . PRO E 5 60  ? 146.819 111.685 115.786 1.00 51.67  ? 60  PRO C C   1 
ATOM 7364 O O   . PRO E 5 60  ? 147.395 112.379 116.634 1.00 51.67  ? 60  PRO C O   1 
ATOM 7365 C CB  . PRO E 5 60  ? 148.101 111.664 113.617 1.00 51.67  ? 60  PRO C CB  1 
ATOM 7366 C CG  . PRO E 5 60  ? 147.096 111.344 112.562 1.00 51.67  ? 60  PRO C CG  1 
ATOM 7367 C CD  . PRO E 5 60  ? 146.702 109.911 112.785 1.00 51.67  ? 60  PRO C CD  1 
ATOM 7368 N N   . PHE E 5 61  ? 145.493 111.650 115.677 1.00 46.58  ? 61  PHE C N   1 
ATOM 7369 C CA  . PHE E 5 61  ? 144.613 112.426 116.539 1.00 46.58  ? 61  PHE C CA  1 
ATOM 7370 C C   . PHE E 5 61  ? 144.033 111.601 117.680 1.00 46.58  ? 61  PHE C C   1 
ATOM 7371 O O   . PHE E 5 61  ? 143.185 112.105 118.424 1.00 46.58  ? 61  PHE C O   1 
ATOM 7372 C CB  . PHE E 5 61  ? 143.482 113.047 115.717 1.00 46.58  ? 61  PHE C CB  1 
ATOM 7373 C CG  . PHE E 5 61  ? 143.957 113.980 114.640 1.00 46.58  ? 61  PHE C CG  1 
ATOM 7374 C CD1 . PHE E 5 61  ? 144.362 115.267 114.948 1.00 46.58  ? 61  PHE C CD1 1 
ATOM 7375 C CD2 . PHE E 5 61  ? 143.994 113.570 113.317 1.00 46.58  ? 61  PHE C CD2 1 
ATOM 7376 C CE1 . PHE E 5 61  ? 144.798 116.128 113.959 1.00 46.58  ? 61  PHE C CE1 1 
ATOM 7377 C CE2 . PHE E 5 61  ? 144.429 114.426 112.324 1.00 46.58  ? 61  PHE C CE2 1 
ATOM 7378 C CZ  . PHE E 5 61  ? 144.832 115.706 112.645 1.00 46.58  ? 61  PHE C CZ  1 
ATOM 7379 N N   . ARG E 5 62  ? 144.470 110.352 117.832 1.00 53.83  ? 62  ARG C N   1 
ATOM 7380 C CA  . ARG E 5 62  ? 143.993 109.460 118.889 1.00 53.83  ? 62  ARG C CA  1 
ATOM 7381 C C   . ARG E 5 62  ? 142.473 109.311 118.865 1.00 53.83  ? 62  ARG C C   1 
ATOM 7382 O O   . ARG E 5 62  ? 141.943 108.349 118.308 1.00 53.83  ? 62  ARG C O   1 
ATOM 7383 C CB  . ARG E 5 62  ? 144.450 109.960 120.262 1.00 53.83  ? 62  ARG C CB  1 
# 
