data_9L2Q
# 
_entry.id   9L2Q 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9L2Q         pdb_00009l2q 10.2210/pdb9l2q/pdb 
WWPDB D_1300054738 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-01-29 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9L2Q 
_pdbx_database_status.recvd_initial_deposition_date   2024-12-17 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              zhangheng134@gmail.com 
_pdbx_contact_author.name_first         Heng 
_pdbx_contact_author.name_last          Zhang 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-1112-7149 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Zhang, H.' 1 ? 
'Liu, Z.'   2 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'hypothetical antiviral protein' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Zhang, H.' 1 ? 
primary 'Liu, Z.'   2 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man H2C2  12014.605 3   ? ? ? ? 
2 water   nat water 18.015    489 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;GMIGSEKQVNWAKSIIEKEVEAWEAIGVDVREVAAFLRSISDARVIIDNRNLIHFQSSGISYSLESSPLNSPIFLRRFSA
CSVGFEEIPTALQRIRSVYTAKLLEDE
;
_entity_poly.pdbx_seq_one_letter_code_can   
;GMIGSEKQVNWAKSIIEKEVEAWEAIGVDVREVAAFLRSISDARVIIDNRNLIHFQSSGISYSLESSPLNSPIFLRRFSA
CSVGFEEIPTALQRIRSVYTAKLLEDE
;
_entity_poly.pdbx_strand_id                 A,B,C 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   2 
_pdbx_entity_nonpoly.name        water 
_pdbx_entity_nonpoly.comp_id     HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   MET n 
1 3   ILE n 
1 4   GLY n 
1 5   SER n 
1 6   GLU n 
1 7   LYS n 
1 8   GLN n 
1 9   VAL n 
1 10  ASN n 
1 11  TRP n 
1 12  ALA n 
1 13  LYS n 
1 14  SER n 
1 15  ILE n 
1 16  ILE n 
1 17  GLU n 
1 18  LYS n 
1 19  GLU n 
1 20  VAL n 
1 21  GLU n 
1 22  ALA n 
1 23  TRP n 
1 24  GLU n 
1 25  ALA n 
1 26  ILE n 
1 27  GLY n 
1 28  VAL n 
1 29  ASP n 
1 30  VAL n 
1 31  ARG n 
1 32  GLU n 
1 33  VAL n 
1 34  ALA n 
1 35  ALA n 
1 36  PHE n 
1 37  LEU n 
1 38  ARG n 
1 39  SER n 
1 40  ILE n 
1 41  SER n 
1 42  ASP n 
1 43  ALA n 
1 44  ARG n 
1 45  VAL n 
1 46  ILE n 
1 47  ILE n 
1 48  ASP n 
1 49  ASN n 
1 50  ARG n 
1 51  ASN n 
1 52  LEU n 
1 53  ILE n 
1 54  HIS n 
1 55  PHE n 
1 56  GLN n 
1 57  SER n 
1 58  SER n 
1 59  GLY n 
1 60  ILE n 
1 61  SER n 
1 62  TYR n 
1 63  SER n 
1 64  LEU n 
1 65  GLU n 
1 66  SER n 
1 67  SER n 
1 68  PRO n 
1 69  LEU n 
1 70  ASN n 
1 71  SER n 
1 72  PRO n 
1 73  ILE n 
1 74  PHE n 
1 75  LEU n 
1 76  ARG n 
1 77  ARG n 
1 78  PHE n 
1 79  SER n 
1 80  ALA n 
1 81  CYS n 
1 82  SER n 
1 83  VAL n 
1 84  GLY n 
1 85  PHE n 
1 86  GLU n 
1 87  GLU n 
1 88  ILE n 
1 89  PRO n 
1 90  THR n 
1 91  ALA n 
1 92  LEU n 
1 93  GLN n 
1 94  ARG n 
1 95  ILE n 
1 96  ARG n 
1 97  SER n 
1 98  VAL n 
1 99  TYR n 
1 100 THR n 
1 101 ALA n 
1 102 LYS n 
1 103 LEU n 
1 104 LEU n 
1 105 GLU n 
1 106 ASP n 
1 107 GLU n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   107 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ? 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Streptococcus macedonicus' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     59310 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER           ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   0   0   GLY GLY A . n 
A 1 2   MET 2   1   1   MET MET A . n 
A 1 3   ILE 3   2   2   ILE ILE A . n 
A 1 4   GLY 4   3   3   GLY GLY A . n 
A 1 5   SER 5   4   4   SER SER A . n 
A 1 6   GLU 6   5   5   GLU GLU A . n 
A 1 7   LYS 7   6   6   LYS LYS A . n 
A 1 8   GLN 8   7   7   GLN GLN A . n 
A 1 9   VAL 9   8   8   VAL VAL A . n 
A 1 10  ASN 10  9   9   ASN ASN A . n 
A 1 11  TRP 11  10  10  TRP TRP A . n 
A 1 12  ALA 12  11  11  ALA ALA A . n 
A 1 13  LYS 13  12  12  LYS LYS A . n 
A 1 14  SER 14  13  13  SER SER A . n 
A 1 15  ILE 15  14  14  ILE ILE A . n 
A 1 16  ILE 16  15  15  ILE ILE A . n 
A 1 17  GLU 17  16  16  GLU GLU A . n 
A 1 18  LYS 18  17  17  LYS LYS A . n 
A 1 19  GLU 19  18  18  GLU GLU A . n 
A 1 20  VAL 20  19  19  VAL VAL A . n 
A 1 21  GLU 21  20  20  GLU GLU A . n 
A 1 22  ALA 22  21  21  ALA ALA A . n 
A 1 23  TRP 23  22  22  TRP TRP A . n 
A 1 24  GLU 24  23  23  GLU GLU A . n 
A 1 25  ALA 25  24  24  ALA ALA A . n 
A 1 26  ILE 26  25  25  ILE ILE A . n 
A 1 27  GLY 27  26  26  GLY GLY A . n 
A 1 28  VAL 28  27  27  VAL VAL A . n 
A 1 29  ASP 29  28  28  ASP ASP A . n 
A 1 30  VAL 30  29  29  VAL VAL A . n 
A 1 31  ARG 31  30  30  ARG ARG A . n 
A 1 32  GLU 32  31  31  GLU GLU A . n 
A 1 33  VAL 33  32  32  VAL VAL A . n 
A 1 34  ALA 34  33  33  ALA ALA A . n 
A 1 35  ALA 35  34  34  ALA ALA A . n 
A 1 36  PHE 36  35  35  PHE PHE A . n 
A 1 37  LEU 37  36  36  LEU LEU A . n 
A 1 38  ARG 38  37  37  ARG ARG A . n 
A 1 39  SER 39  38  38  SER SER A . n 
A 1 40  ILE 40  39  39  ILE ILE A . n 
A 1 41  SER 41  40  40  SER SER A . n 
A 1 42  ASP 42  41  41  ASP ASP A . n 
A 1 43  ALA 43  42  42  ALA ALA A . n 
A 1 44  ARG 44  43  43  ARG ARG A . n 
A 1 45  VAL 45  44  44  VAL VAL A . n 
A 1 46  ILE 46  45  45  ILE ILE A . n 
A 1 47  ILE 47  46  46  ILE ILE A . n 
A 1 48  ASP 48  47  47  ASP ASP A . n 
A 1 49  ASN 49  48  48  ASN ASN A . n 
A 1 50  ARG 50  49  49  ARG ARG A . n 
A 1 51  ASN 51  50  50  ASN ASN A . n 
A 1 52  LEU 52  51  51  LEU LEU A . n 
A 1 53  ILE 53  52  52  ILE ILE A . n 
A 1 54  HIS 54  53  53  HIS HIS A . n 
A 1 55  PHE 55  54  54  PHE PHE A . n 
A 1 56  GLN 56  55  55  GLN GLN A . n 
A 1 57  SER 57  56  56  SER SER A . n 
A 1 58  SER 58  57  57  SER SER A . n 
A 1 59  GLY 59  58  58  GLY GLY A . n 
A 1 60  ILE 60  59  59  ILE ILE A . n 
A 1 61  SER 61  60  60  SER SER A . n 
A 1 62  TYR 62  61  61  TYR TYR A . n 
A 1 63  SER 63  62  62  SER SER A . n 
A 1 64  LEU 64  63  63  LEU LEU A . n 
A 1 65  GLU 65  64  64  GLU GLU A . n 
A 1 66  SER 66  65  65  SER SER A . n 
A 1 67  SER 67  66  66  SER SER A . n 
A 1 68  PRO 68  67  67  PRO PRO A . n 
A 1 69  LEU 69  68  68  LEU LEU A . n 
A 1 70  ASN 70  69  69  ASN ASN A . n 
A 1 71  SER 71  70  70  SER SER A . n 
A 1 72  PRO 72  71  71  PRO PRO A . n 
A 1 73  ILE 73  72  72  ILE ILE A . n 
A 1 74  PHE 74  73  73  PHE PHE A . n 
A 1 75  LEU 75  74  74  LEU LEU A . n 
A 1 76  ARG 76  75  75  ARG ARG A . n 
A 1 77  ARG 77  76  76  ARG ARG A . n 
A 1 78  PHE 78  77  77  PHE PHE A . n 
A 1 79  SER 79  78  78  SER SER A . n 
A 1 80  ALA 80  79  79  ALA ALA A . n 
A 1 81  CYS 81  80  80  CYS CYS A . n 
A 1 82  SER 82  81  81  SER SER A . n 
A 1 83  VAL 83  82  82  VAL VAL A . n 
A 1 84  GLY 84  83  83  GLY GLY A . n 
A 1 85  PHE 85  84  84  PHE PHE A . n 
A 1 86  GLU 86  85  85  GLU GLU A . n 
A 1 87  GLU 87  86  86  GLU GLU A . n 
A 1 88  ILE 88  87  87  ILE ILE A . n 
A 1 89  PRO 89  88  88  PRO PRO A . n 
A 1 90  THR 90  89  89  THR THR A . n 
A 1 91  ALA 91  90  90  ALA ALA A . n 
A 1 92  LEU 92  91  91  LEU LEU A . n 
A 1 93  GLN 93  92  92  GLN GLN A . n 
A 1 94  ARG 94  93  93  ARG ARG A . n 
A 1 95  ILE 95  94  94  ILE ILE A . n 
A 1 96  ARG 96  95  95  ARG ARG A . n 
A 1 97  SER 97  96  96  SER SER A . n 
A 1 98  VAL 98  97  97  VAL VAL A . n 
A 1 99  TYR 99  98  98  TYR TYR A . n 
A 1 100 THR 100 99  99  THR THR A . n 
A 1 101 ALA 101 100 100 ALA ALA A . n 
A 1 102 LYS 102 101 101 LYS LYS A . n 
A 1 103 LEU 103 102 102 LEU LEU A . n 
A 1 104 LEU 104 103 103 LEU LEU A . n 
A 1 105 GLU 105 104 104 GLU GLU A . n 
A 1 106 ASP 106 105 ?   ?   ?   A . n 
A 1 107 GLU 107 106 ?   ?   ?   A . n 
B 1 1   GLY 1   0   0   GLY GLY B . n 
B 1 2   MET 2   1   1   MET MET B . n 
B 1 3   ILE 3   2   2   ILE ILE B . n 
B 1 4   GLY 4   3   3   GLY GLY B . n 
B 1 5   SER 5   4   4   SER SER B . n 
B 1 6   GLU 6   5   5   GLU GLU B . n 
B 1 7   LYS 7   6   6   LYS LYS B . n 
B 1 8   GLN 8   7   7   GLN GLN B . n 
B 1 9   VAL 9   8   8   VAL VAL B . n 
B 1 10  ASN 10  9   9   ASN ASN B . n 
B 1 11  TRP 11  10  10  TRP TRP B . n 
B 1 12  ALA 12  11  11  ALA ALA B . n 
B 1 13  LYS 13  12  12  LYS LYS B . n 
B 1 14  SER 14  13  13  SER SER B . n 
B 1 15  ILE 15  14  14  ILE ILE B . n 
B 1 16  ILE 16  15  15  ILE ILE B . n 
B 1 17  GLU 17  16  16  GLU GLU B . n 
B 1 18  LYS 18  17  17  LYS LYS B . n 
B 1 19  GLU 19  18  18  GLU GLU B . n 
B 1 20  VAL 20  19  19  VAL VAL B . n 
B 1 21  GLU 21  20  20  GLU GLU B . n 
B 1 22  ALA 22  21  21  ALA ALA B . n 
B 1 23  TRP 23  22  22  TRP TRP B . n 
B 1 24  GLU 24  23  23  GLU GLU B . n 
B 1 25  ALA 25  24  24  ALA ALA B . n 
B 1 26  ILE 26  25  25  ILE ILE B . n 
B 1 27  GLY 27  26  26  GLY GLY B . n 
B 1 28  VAL 28  27  27  VAL VAL B . n 
B 1 29  ASP 29  28  28  ASP ASP B . n 
B 1 30  VAL 30  29  29  VAL VAL B . n 
B 1 31  ARG 31  30  30  ARG ARG B . n 
B 1 32  GLU 32  31  31  GLU GLU B . n 
B 1 33  VAL 33  32  32  VAL VAL B . n 
B 1 34  ALA 34  33  33  ALA ALA B . n 
B 1 35  ALA 35  34  34  ALA ALA B . n 
B 1 36  PHE 36  35  35  PHE PHE B . n 
B 1 37  LEU 37  36  36  LEU LEU B . n 
B 1 38  ARG 38  37  37  ARG ARG B . n 
B 1 39  SER 39  38  38  SER SER B . n 
B 1 40  ILE 40  39  39  ILE ILE B . n 
B 1 41  SER 41  40  40  SER SER B . n 
B 1 42  ASP 42  41  41  ASP ASP B . n 
B 1 43  ALA 43  42  42  ALA ALA B . n 
B 1 44  ARG 44  43  43  ARG ARG B . n 
B 1 45  VAL 45  44  44  VAL VAL B . n 
B 1 46  ILE 46  45  45  ILE ILE B . n 
B 1 47  ILE 47  46  46  ILE ILE B . n 
B 1 48  ASP 48  47  47  ASP ASP B . n 
B 1 49  ASN 49  48  48  ASN ASN B . n 
B 1 50  ARG 50  49  49  ARG ARG B . n 
B 1 51  ASN 51  50  50  ASN ASN B . n 
B 1 52  LEU 52  51  51  LEU LEU B . n 
B 1 53  ILE 53  52  52  ILE ILE B . n 
B 1 54  HIS 54  53  53  HIS HIS B . n 
B 1 55  PHE 55  54  54  PHE PHE B . n 
B 1 56  GLN 56  55  55  GLN GLN B . n 
B 1 57  SER 57  56  56  SER SER B . n 
B 1 58  SER 58  57  57  SER SER B . n 
B 1 59  GLY 59  58  58  GLY GLY B . n 
B 1 60  ILE 60  59  59  ILE ILE B . n 
B 1 61  SER 61  60  60  SER SER B . n 
B 1 62  TYR 62  61  61  TYR TYR B . n 
B 1 63  SER 63  62  62  SER SER B . n 
B 1 64  LEU 64  63  63  LEU LEU B . n 
B 1 65  GLU 65  64  64  GLU GLU B . n 
B 1 66  SER 66  65  65  SER SER B . n 
B 1 67  SER 67  66  66  SER SER B . n 
B 1 68  PRO 68  67  67  PRO PRO B . n 
B 1 69  LEU 69  68  68  LEU LEU B . n 
B 1 70  ASN 70  69  69  ASN ASN B . n 
B 1 71  SER 71  70  70  SER SER B . n 
B 1 72  PRO 72  71  71  PRO PRO B . n 
B 1 73  ILE 73  72  72  ILE ILE B . n 
B 1 74  PHE 74  73  73  PHE PHE B . n 
B 1 75  LEU 75  74  74  LEU LEU B . n 
B 1 76  ARG 76  75  75  ARG ARG B . n 
B 1 77  ARG 77  76  76  ARG ARG B . n 
B 1 78  PHE 78  77  77  PHE PHE B . n 
B 1 79  SER 79  78  78  SER SER B . n 
B 1 80  ALA 80  79  79  ALA ALA B . n 
B 1 81  CYS 81  80  80  CYS CYS B . n 
B 1 82  SER 82  81  81  SER SER B . n 
B 1 83  VAL 83  82  82  VAL VAL B . n 
B 1 84  GLY 84  83  83  GLY GLY B . n 
B 1 85  PHE 85  84  84  PHE PHE B . n 
B 1 86  GLU 86  85  85  GLU GLU B . n 
B 1 87  GLU 87  86  86  GLU GLU B . n 
B 1 88  ILE 88  87  87  ILE ILE B . n 
B 1 89  PRO 89  88  88  PRO PRO B . n 
B 1 90  THR 90  89  89  THR THR B . n 
B 1 91  ALA 91  90  90  ALA ALA B . n 
B 1 92  LEU 92  91  91  LEU LEU B . n 
B 1 93  GLN 93  92  92  GLN GLN B . n 
B 1 94  ARG 94  93  93  ARG ARG B . n 
B 1 95  ILE 95  94  94  ILE ILE B . n 
B 1 96  ARG 96  95  95  ARG ARG B . n 
B 1 97  SER 97  96  96  SER SER B . n 
B 1 98  VAL 98  97  97  VAL VAL B . n 
B 1 99  TYR 99  98  98  TYR TYR B . n 
B 1 100 THR 100 99  99  THR THR B . n 
B 1 101 ALA 101 100 100 ALA ALA B . n 
B 1 102 LYS 102 101 101 LYS LYS B . n 
B 1 103 LEU 103 102 102 LEU LEU B . n 
B 1 104 LEU 104 103 103 LEU LEU B . n 
B 1 105 GLU 105 104 104 GLU GLU B . n 
B 1 106 ASP 106 105 ?   ?   ?   B . n 
B 1 107 GLU 107 106 ?   ?   ?   B . n 
C 1 1   GLY 1   0   0   GLY GLY C . n 
C 1 2   MET 2   1   1   MET MET C . n 
C 1 3   ILE 3   2   2   ILE ILE C . n 
C 1 4   GLY 4   3   3   GLY GLY C . n 
C 1 5   SER 5   4   4   SER SER C . n 
C 1 6   GLU 6   5   5   GLU GLU C . n 
C 1 7   LYS 7   6   6   LYS LYS C . n 
C 1 8   GLN 8   7   7   GLN GLN C . n 
C 1 9   VAL 9   8   8   VAL VAL C . n 
C 1 10  ASN 10  9   9   ASN ASN C . n 
C 1 11  TRP 11  10  10  TRP TRP C . n 
C 1 12  ALA 12  11  11  ALA ALA C . n 
C 1 13  LYS 13  12  12  LYS LYS C . n 
C 1 14  SER 14  13  13  SER SER C . n 
C 1 15  ILE 15  14  14  ILE ILE C . n 
C 1 16  ILE 16  15  15  ILE ILE C . n 
C 1 17  GLU 17  16  16  GLU GLU C . n 
C 1 18  LYS 18  17  17  LYS LYS C . n 
C 1 19  GLU 19  18  18  GLU GLU C . n 
C 1 20  VAL 20  19  19  VAL VAL C . n 
C 1 21  GLU 21  20  20  GLU GLU C . n 
C 1 22  ALA 22  21  21  ALA ALA C . n 
C 1 23  TRP 23  22  22  TRP TRP C . n 
C 1 24  GLU 24  23  23  GLU GLU C . n 
C 1 25  ALA 25  24  24  ALA ALA C . n 
C 1 26  ILE 26  25  25  ILE ILE C . n 
C 1 27  GLY 27  26  26  GLY GLY C . n 
C 1 28  VAL 28  27  27  VAL VAL C . n 
C 1 29  ASP 29  28  28  ASP ASP C . n 
C 1 30  VAL 30  29  29  VAL VAL C . n 
C 1 31  ARG 31  30  30  ARG ARG C . n 
C 1 32  GLU 32  31  31  GLU GLU C . n 
C 1 33  VAL 33  32  32  VAL VAL C . n 
C 1 34  ALA 34  33  33  ALA ALA C . n 
C 1 35  ALA 35  34  34  ALA ALA C . n 
C 1 36  PHE 36  35  35  PHE PHE C . n 
C 1 37  LEU 37  36  36  LEU LEU C . n 
C 1 38  ARG 38  37  37  ARG ARG C . n 
C 1 39  SER 39  38  38  SER SER C . n 
C 1 40  ILE 40  39  39  ILE ILE C . n 
C 1 41  SER 41  40  40  SER SER C . n 
C 1 42  ASP 42  41  41  ASP ASP C . n 
C 1 43  ALA 43  42  42  ALA ALA C . n 
C 1 44  ARG 44  43  43  ARG ARG C . n 
C 1 45  VAL 45  44  44  VAL VAL C . n 
C 1 46  ILE 46  45  45  ILE ILE C . n 
C 1 47  ILE 47  46  46  ILE ILE C . n 
C 1 48  ASP 48  47  47  ASP ASP C . n 
C 1 49  ASN 49  48  48  ASN ASN C . n 
C 1 50  ARG 50  49  49  ARG ARG C . n 
C 1 51  ASN 51  50  50  ASN ASN C . n 
C 1 52  LEU 52  51  51  LEU LEU C . n 
C 1 53  ILE 53  52  52  ILE ILE C . n 
C 1 54  HIS 54  53  53  HIS HIS C . n 
C 1 55  PHE 55  54  54  PHE PHE C . n 
C 1 56  GLN 56  55  55  GLN GLN C . n 
C 1 57  SER 57  56  56  SER SER C . n 
C 1 58  SER 58  57  57  SER SER C . n 
C 1 59  GLY 59  58  58  GLY GLY C . n 
C 1 60  ILE 60  59  59  ILE ILE C . n 
C 1 61  SER 61  60  60  SER SER C . n 
C 1 62  TYR 62  61  61  TYR TYR C . n 
C 1 63  SER 63  62  62  SER SER C . n 
C 1 64  LEU 64  63  63  LEU LEU C . n 
C 1 65  GLU 65  64  64  GLU GLU C . n 
C 1 66  SER 66  65  65  SER SER C . n 
C 1 67  SER 67  66  66  SER SER C . n 
C 1 68  PRO 68  67  67  PRO PRO C . n 
C 1 69  LEU 69  68  68  LEU LEU C . n 
C 1 70  ASN 70  69  69  ASN ASN C . n 
C 1 71  SER 71  70  70  SER SER C . n 
C 1 72  PRO 72  71  71  PRO PRO C . n 
C 1 73  ILE 73  72  72  ILE ILE C . n 
C 1 74  PHE 74  73  73  PHE PHE C . n 
C 1 75  LEU 75  74  74  LEU LEU C . n 
C 1 76  ARG 76  75  75  ARG ARG C . n 
C 1 77  ARG 77  76  76  ARG ARG C . n 
C 1 78  PHE 78  77  77  PHE PHE C . n 
C 1 79  SER 79  78  78  SER SER C . n 
C 1 80  ALA 80  79  79  ALA ALA C . n 
C 1 81  CYS 81  80  80  CYS CYS C . n 
C 1 82  SER 82  81  81  SER SER C . n 
C 1 83  VAL 83  82  82  VAL VAL C . n 
C 1 84  GLY 84  83  83  GLY GLY C . n 
C 1 85  PHE 85  84  84  PHE PHE C . n 
C 1 86  GLU 86  85  85  GLU GLU C . n 
C 1 87  GLU 87  86  86  GLU GLU C . n 
C 1 88  ILE 88  87  87  ILE ILE C . n 
C 1 89  PRO 89  88  88  PRO PRO C . n 
C 1 90  THR 90  89  89  THR THR C . n 
C 1 91  ALA 91  90  90  ALA ALA C . n 
C 1 92  LEU 92  91  91  LEU LEU C . n 
C 1 93  GLN 93  92  92  GLN GLN C . n 
C 1 94  ARG 94  93  93  ARG ARG C . n 
C 1 95  ILE 95  94  94  ILE ILE C . n 
C 1 96  ARG 96  95  95  ARG ARG C . n 
C 1 97  SER 97  96  96  SER SER C . n 
C 1 98  VAL 98  97  97  VAL VAL C . n 
C 1 99  TYR 99  98  98  TYR TYR C . n 
C 1 100 THR 100 99  99  THR THR C . n 
C 1 101 ALA 101 100 100 ALA ALA C . n 
C 1 102 LYS 102 101 101 LYS LYS C . n 
C 1 103 LEU 103 102 102 LEU LEU C . n 
C 1 104 LEU 104 103 103 LEU LEU C . n 
C 1 105 GLU 105 104 104 GLU GLU C . n 
C 1 106 ASP 106 105 ?   ?   ?   C . n 
C 1 107 GLU 107 106 ?   ?   ?   C . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
D 2 HOH 1   201 70  HOH HOH A . 
D 2 HOH 2   202 119 HOH HOH A . 
D 2 HOH 3   203 351 HOH HOH A . 
D 2 HOH 4   204 202 HOH HOH A . 
D 2 HOH 5   205 212 HOH HOH A . 
D 2 HOH 6   206 123 HOH HOH A . 
D 2 HOH 7   207 251 HOH HOH A . 
D 2 HOH 8   208 39  HOH HOH A . 
D 2 HOH 9   209 185 HOH HOH A . 
D 2 HOH 10  210 191 HOH HOH A . 
D 2 HOH 11  211 141 HOH HOH A . 
D 2 HOH 12  212 164 HOH HOH A . 
D 2 HOH 13  213 442 HOH HOH A . 
D 2 HOH 14  214 54  HOH HOH A . 
D 2 HOH 15  215 15  HOH HOH A . 
D 2 HOH 16  216 23  HOH HOH A . 
D 2 HOH 17  217 411 HOH HOH A . 
D 2 HOH 18  218 113 HOH HOH A . 
D 2 HOH 19  219 163 HOH HOH A . 
D 2 HOH 20  220 238 HOH HOH A . 
D 2 HOH 21  221 19  HOH HOH A . 
D 2 HOH 22  222 6   HOH HOH A . 
D 2 HOH 23  223 56  HOH HOH A . 
D 2 HOH 24  224 174 HOH HOH A . 
D 2 HOH 25  225 129 HOH HOH A . 
D 2 HOH 26  226 26  HOH HOH A . 
D 2 HOH 27  227 220 HOH HOH A . 
D 2 HOH 28  228 125 HOH HOH A . 
D 2 HOH 29  229 216 HOH HOH A . 
D 2 HOH 30  230 45  HOH HOH A . 
D 2 HOH 31  231 233 HOH HOH A . 
D 2 HOH 32  232 92  HOH HOH A . 
D 2 HOH 33  233 51  HOH HOH A . 
D 2 HOH 34  234 104 HOH HOH A . 
D 2 HOH 35  235 365 HOH HOH A . 
D 2 HOH 36  236 299 HOH HOH A . 
D 2 HOH 37  237 429 HOH HOH A . 
D 2 HOH 38  238 441 HOH HOH A . 
D 2 HOH 39  239 357 HOH HOH A . 
D 2 HOH 40  240 12  HOH HOH A . 
D 2 HOH 41  241 62  HOH HOH A . 
D 2 HOH 42  242 76  HOH HOH A . 
D 2 HOH 43  243 4   HOH HOH A . 
D 2 HOH 44  244 65  HOH HOH A . 
D 2 HOH 45  245 29  HOH HOH A . 
D 2 HOH 46  246 307 HOH HOH A . 
D 2 HOH 47  247 189 HOH HOH A . 
D 2 HOH 48  248 439 HOH HOH A . 
D 2 HOH 49  249 107 HOH HOH A . 
D 2 HOH 50  250 7   HOH HOH A . 
D 2 HOH 51  251 194 HOH HOH A . 
D 2 HOH 52  252 321 HOH HOH A . 
D 2 HOH 53  253 223 HOH HOH A . 
D 2 HOH 54  254 13  HOH HOH A . 
D 2 HOH 55  255 86  HOH HOH A . 
D 2 HOH 56  256 34  HOH HOH A . 
D 2 HOH 57  257 38  HOH HOH A . 
D 2 HOH 58  258 219 HOH HOH A . 
D 2 HOH 59  259 332 HOH HOH A . 
D 2 HOH 60  260 356 HOH HOH A . 
D 2 HOH 61  261 277 HOH HOH A . 
D 2 HOH 62  262 265 HOH HOH A . 
D 2 HOH 63  263 3   HOH HOH A . 
D 2 HOH 64  264 91  HOH HOH A . 
D 2 HOH 65  265 67  HOH HOH A . 
D 2 HOH 66  266 291 HOH HOH A . 
D 2 HOH 67  267 346 HOH HOH A . 
D 2 HOH 68  268 175 HOH HOH A . 
D 2 HOH 69  269 74  HOH HOH A . 
D 2 HOH 70  270 167 HOH HOH A . 
D 2 HOH 71  271 58  HOH HOH A . 
D 2 HOH 72  272 179 HOH HOH A . 
D 2 HOH 73  273 81  HOH HOH A . 
D 2 HOH 74  274 170 HOH HOH A . 
D 2 HOH 75  275 28  HOH HOH A . 
D 2 HOH 76  276 273 HOH HOH A . 
D 2 HOH 77  277 350 HOH HOH A . 
D 2 HOH 78  278 178 HOH HOH A . 
D 2 HOH 79  279 127 HOH HOH A . 
D 2 HOH 80  280 195 HOH HOH A . 
D 2 HOH 81  281 444 HOH HOH A . 
D 2 HOH 82  282 214 HOH HOH A . 
D 2 HOH 83  283 100 HOH HOH A . 
D 2 HOH 84  284 294 HOH HOH A . 
D 2 HOH 85  285 114 HOH HOH A . 
D 2 HOH 86  286 310 HOH HOH A . 
D 2 HOH 87  287 112 HOH HOH A . 
D 2 HOH 88  288 44  HOH HOH A . 
D 2 HOH 89  289 207 HOH HOH A . 
D 2 HOH 90  290 49  HOH HOH A . 
D 2 HOH 91  291 98  HOH HOH A . 
D 2 HOH 92  292 16  HOH HOH A . 
D 2 HOH 93  293 462 HOH HOH A . 
D 2 HOH 94  294 230 HOH HOH A . 
D 2 HOH 95  295 418 HOH HOH A . 
D 2 HOH 96  296 71  HOH HOH A . 
D 2 HOH 97  297 274 HOH HOH A . 
D 2 HOH 98  298 60  HOH HOH A . 
D 2 HOH 99  299 372 HOH HOH A . 
D 2 HOH 100 300 241 HOH HOH A . 
D 2 HOH 101 301 235 HOH HOH A . 
D 2 HOH 102 302 148 HOH HOH A . 
D 2 HOH 103 303 464 HOH HOH A . 
D 2 HOH 104 304 275 HOH HOH A . 
D 2 HOH 105 305 242 HOH HOH A . 
D 2 HOH 106 306 390 HOH HOH A . 
D 2 HOH 107 307 155 HOH HOH A . 
D 2 HOH 108 308 489 HOH HOH A . 
D 2 HOH 109 309 115 HOH HOH A . 
D 2 HOH 110 310 79  HOH HOH A . 
D 2 HOH 111 311 118 HOH HOH A . 
D 2 HOH 112 312 1   HOH HOH A . 
D 2 HOH 113 313 393 HOH HOH A . 
D 2 HOH 114 314 259 HOH HOH A . 
D 2 HOH 115 315 183 HOH HOH A . 
D 2 HOH 116 316 95  HOH HOH A . 
D 2 HOH 117 317 450 HOH HOH A . 
D 2 HOH 118 318 445 HOH HOH A . 
D 2 HOH 119 319 340 HOH HOH A . 
D 2 HOH 120 320 452 HOH HOH A . 
D 2 HOH 121 321 323 HOH HOH A . 
D 2 HOH 122 322 83  HOH HOH A . 
D 2 HOH 123 323 435 HOH HOH A . 
D 2 HOH 124 324 144 HOH HOH A . 
D 2 HOH 125 325 396 HOH HOH A . 
D 2 HOH 126 326 279 HOH HOH A . 
D 2 HOH 127 327 331 HOH HOH A . 
D 2 HOH 128 328 134 HOH HOH A . 
D 2 HOH 129 329 479 HOH HOH A . 
D 2 HOH 130 330 370 HOH HOH A . 
D 2 HOH 131 331 320 HOH HOH A . 
D 2 HOH 132 332 473 HOH HOH A . 
D 2 HOH 133 333 487 HOH HOH A . 
D 2 HOH 134 334 302 HOH HOH A . 
D 2 HOH 135 335 427 HOH HOH A . 
D 2 HOH 136 336 328 HOH HOH A . 
D 2 HOH 137 337 244 HOH HOH A . 
D 2 HOH 138 338 374 HOH HOH A . 
D 2 HOH 139 339 465 HOH HOH A . 
D 2 HOH 140 340 270 HOH HOH A . 
D 2 HOH 141 341 316 HOH HOH A . 
D 2 HOH 142 342 166 HOH HOH A . 
D 2 HOH 143 343 266 HOH HOH A . 
D 2 HOH 144 344 281 HOH HOH A . 
D 2 HOH 145 345 334 HOH HOH A . 
D 2 HOH 146 346 381 HOH HOH A . 
D 2 HOH 147 347 63  HOH HOH A . 
D 2 HOH 148 348 319 HOH HOH A . 
D 2 HOH 149 349 375 HOH HOH A . 
D 2 HOH 150 350 392 HOH HOH A . 
D 2 HOH 151 351 308 HOH HOH A . 
D 2 HOH 152 352 400 HOH HOH A . 
D 2 HOH 153 353 203 HOH HOH A . 
D 2 HOH 154 354 211 HOH HOH A . 
D 2 HOH 155 355 416 HOH HOH A . 
D 2 HOH 156 356 421 HOH HOH A . 
D 2 HOH 157 357 154 HOH HOH A . 
D 2 HOH 158 358 192 HOH HOH A . 
D 2 HOH 159 359 253 HOH HOH A . 
D 2 HOH 160 360 93  HOH HOH A . 
D 2 HOH 161 361 412 HOH HOH A . 
D 2 HOH 162 362 236 HOH HOH A . 
D 2 HOH 163 363 353 HOH HOH A . 
D 2 HOH 164 364 301 HOH HOH A . 
D 2 HOH 165 365 426 HOH HOH A . 
D 2 HOH 166 366 245 HOH HOH A . 
D 2 HOH 167 367 47  HOH HOH A . 
D 2 HOH 168 368 217 HOH HOH A . 
D 2 HOH 169 369 132 HOH HOH A . 
D 2 HOH 170 370 378 HOH HOH A . 
D 2 HOH 171 371 463 HOH HOH A . 
E 2 HOH 1   201 130 HOH HOH B . 
E 2 HOH 2   202 133 HOH HOH B . 
E 2 HOH 3   203 10  HOH HOH B . 
E 2 HOH 4   204 333 HOH HOH B . 
E 2 HOH 5   205 449 HOH HOH B . 
E 2 HOH 6   206 116 HOH HOH B . 
E 2 HOH 7   207 237 HOH HOH B . 
E 2 HOH 8   208 200 HOH HOH B . 
E 2 HOH 9   209 42  HOH HOH B . 
E 2 HOH 10  210 181 HOH HOH B . 
E 2 HOH 11  211 5   HOH HOH B . 
E 2 HOH 12  212 106 HOH HOH B . 
E 2 HOH 13  213 77  HOH HOH B . 
E 2 HOH 14  214 209 HOH HOH B . 
E 2 HOH 15  215 171 HOH HOH B . 
E 2 HOH 16  216 46  HOH HOH B . 
E 2 HOH 17  217 68  HOH HOH B . 
E 2 HOH 18  218 161 HOH HOH B . 
E 2 HOH 19  219 483 HOH HOH B . 
E 2 HOH 20  220 147 HOH HOH B . 
E 2 HOH 21  221 153 HOH HOH B . 
E 2 HOH 22  222 190 HOH HOH B . 
E 2 HOH 23  223 124 HOH HOH B . 
E 2 HOH 24  224 327 HOH HOH B . 
E 2 HOH 25  225 271 HOH HOH B . 
E 2 HOH 26  226 425 HOH HOH B . 
E 2 HOH 27  227 456 HOH HOH B . 
E 2 HOH 28  228 476 HOH HOH B . 
E 2 HOH 29  229 55  HOH HOH B . 
E 2 HOH 30  230 90  HOH HOH B . 
E 2 HOH 31  231 369 HOH HOH B . 
E 2 HOH 32  232 21  HOH HOH B . 
E 2 HOH 33  233 142 HOH HOH B . 
E 2 HOH 34  234 145 HOH HOH B . 
E 2 HOH 35  235 165 HOH HOH B . 
E 2 HOH 36  236 188 HOH HOH B . 
E 2 HOH 37  237 31  HOH HOH B . 
E 2 HOH 38  238 342 HOH HOH B . 
E 2 HOH 39  239 269 HOH HOH B . 
E 2 HOH 40  240 159 HOH HOH B . 
E 2 HOH 41  241 213 HOH HOH B . 
E 2 HOH 42  242 33  HOH HOH B . 
E 2 HOH 43  243 325 HOH HOH B . 
E 2 HOH 44  244 278 HOH HOH B . 
E 2 HOH 45  245 35  HOH HOH B . 
E 2 HOH 46  246 17  HOH HOH B . 
E 2 HOH 47  247 61  HOH HOH B . 
E 2 HOH 48  248 22  HOH HOH B . 
E 2 HOH 49  249 261 HOH HOH B . 
E 2 HOH 50  250 82  HOH HOH B . 
E 2 HOH 51  251 341 HOH HOH B . 
E 2 HOH 52  252 160 HOH HOH B . 
E 2 HOH 53  253 434 HOH HOH B . 
E 2 HOH 54  254 149 HOH HOH B . 
E 2 HOH 55  255 312 HOH HOH B . 
E 2 HOH 56  256 78  HOH HOH B . 
E 2 HOH 57  257 41  HOH HOH B . 
E 2 HOH 58  258 247 HOH HOH B . 
E 2 HOH 59  259 262 HOH HOH B . 
E 2 HOH 60  260 40  HOH HOH B . 
E 2 HOH 61  261 157 HOH HOH B . 
E 2 HOH 62  262 43  HOH HOH B . 
E 2 HOH 63  263 87  HOH HOH B . 
E 2 HOH 64  264 89  HOH HOH B . 
E 2 HOH 65  265 168 HOH HOH B . 
E 2 HOH 66  266 379 HOH HOH B . 
E 2 HOH 67  267 451 HOH HOH B . 
E 2 HOH 68  268 424 HOH HOH B . 
E 2 HOH 69  269 305 HOH HOH B . 
E 2 HOH 70  270 199 HOH HOH B . 
E 2 HOH 71  271 292 HOH HOH B . 
E 2 HOH 72  272 173 HOH HOH B . 
E 2 HOH 73  273 447 HOH HOH B . 
E 2 HOH 74  274 272 HOH HOH B . 
E 2 HOH 75  275 73  HOH HOH B . 
E 2 HOH 76  276 367 HOH HOH B . 
E 2 HOH 77  277 205 HOH HOH B . 
E 2 HOH 78  278 453 HOH HOH B . 
E 2 HOH 79  279 336 HOH HOH B . 
E 2 HOH 80  280 222 HOH HOH B . 
E 2 HOH 81  281 354 HOH HOH B . 
E 2 HOH 82  282 120 HOH HOH B . 
E 2 HOH 83  283 280 HOH HOH B . 
E 2 HOH 84  284 380 HOH HOH B . 
E 2 HOH 85  285 461 HOH HOH B . 
E 2 HOH 86  286 197 HOH HOH B . 
E 2 HOH 87  287 53  HOH HOH B . 
E 2 HOH 88  288 206 HOH HOH B . 
E 2 HOH 89  289 298 HOH HOH B . 
E 2 HOH 90  290 395 HOH HOH B . 
E 2 HOH 91  291 382 HOH HOH B . 
E 2 HOH 92  292 401 HOH HOH B . 
E 2 HOH 93  293 187 HOH HOH B . 
E 2 HOH 94  294 176 HOH HOH B . 
E 2 HOH 95  295 317 HOH HOH B . 
E 2 HOH 96  296 121 HOH HOH B . 
E 2 HOH 97  297 311 HOH HOH B . 
E 2 HOH 98  298 314 HOH HOH B . 
E 2 HOH 99  299 59  HOH HOH B . 
E 2 HOH 100 300 69  HOH HOH B . 
E 2 HOH 101 301 326 HOH HOH B . 
E 2 HOH 102 302 482 HOH HOH B . 
E 2 HOH 103 303 403 HOH HOH B . 
E 2 HOH 104 304 263 HOH HOH B . 
E 2 HOH 105 305 225 HOH HOH B . 
E 2 HOH 106 306 488 HOH HOH B . 
E 2 HOH 107 307 180 HOH HOH B . 
E 2 HOH 108 308 295 HOH HOH B . 
E 2 HOH 109 309 384 HOH HOH B . 
E 2 HOH 110 310 103 HOH HOH B . 
E 2 HOH 111 311 126 HOH HOH B . 
E 2 HOH 112 312 388 HOH HOH B . 
E 2 HOH 113 313 248 HOH HOH B . 
E 2 HOH 114 314 352 HOH HOH B . 
E 2 HOH 115 315 455 HOH HOH B . 
E 2 HOH 116 316 300 HOH HOH B . 
E 2 HOH 117 317 2   HOH HOH B . 
E 2 HOH 118 318 276 HOH HOH B . 
E 2 HOH 119 319 407 HOH HOH B . 
E 2 HOH 120 320 287 HOH HOH B . 
E 2 HOH 121 321 406 HOH HOH B . 
E 2 HOH 122 322 467 HOH HOH B . 
E 2 HOH 123 323 136 HOH HOH B . 
E 2 HOH 124 324 366 HOH HOH B . 
E 2 HOH 125 325 337 HOH HOH B . 
E 2 HOH 126 326 373 HOH HOH B . 
E 2 HOH 127 327 475 HOH HOH B . 
E 2 HOH 128 328 386 HOH HOH B . 
E 2 HOH 129 329 368 HOH HOH B . 
E 2 HOH 130 330 438 HOH HOH B . 
E 2 HOH 131 331 306 HOH HOH B . 
E 2 HOH 132 332 282 HOH HOH B . 
E 2 HOH 133 333 290 HOH HOH B . 
E 2 HOH 134 334 397 HOH HOH B . 
E 2 HOH 135 335 446 HOH HOH B . 
E 2 HOH 136 336 226 HOH HOH B . 
E 2 HOH 137 337 405 HOH HOH B . 
E 2 HOH 138 338 454 HOH HOH B . 
E 2 HOH 139 339 358 HOH HOH B . 
E 2 HOH 140 340 430 HOH HOH B . 
E 2 HOH 141 341 313 HOH HOH B . 
E 2 HOH 142 342 218 HOH HOH B . 
E 2 HOH 143 343 284 HOH HOH B . 
E 2 HOH 144 344 322 HOH HOH B . 
E 2 HOH 145 345 387 HOH HOH B . 
E 2 HOH 146 346 158 HOH HOH B . 
E 2 HOH 147 347 474 HOH HOH B . 
E 2 HOH 148 348 415 HOH HOH B . 
E 2 HOH 149 349 472 HOH HOH B . 
E 2 HOH 150 350 399 HOH HOH B . 
E 2 HOH 151 351 413 HOH HOH B . 
E 2 HOH 152 352 478 HOH HOH B . 
E 2 HOH 153 353 377 HOH HOH B . 
E 2 HOH 154 354 254 HOH HOH B . 
E 2 HOH 155 355 9   HOH HOH B . 
E 2 HOH 156 356 363 HOH HOH B . 
F 2 HOH 1   201 361 HOH HOH C . 
F 2 HOH 2   202 193 HOH HOH C . 
F 2 HOH 3   203 184 HOH HOH C . 
F 2 HOH 4   204 288 HOH HOH C . 
F 2 HOH 5   205 440 HOH HOH C . 
F 2 HOH 6   206 84  HOH HOH C . 
F 2 HOH 7   207 285 HOH HOH C . 
F 2 HOH 8   208 448 HOH HOH C . 
F 2 HOH 9   209 221 HOH HOH C . 
F 2 HOH 10  210 232 HOH HOH C . 
F 2 HOH 11  211 27  HOH HOH C . 
F 2 HOH 12  212 250 HOH HOH C . 
F 2 HOH 13  213 32  HOH HOH C . 
F 2 HOH 14  214 110 HOH HOH C . 
F 2 HOH 15  215 404 HOH HOH C . 
F 2 HOH 16  216 64  HOH HOH C . 
F 2 HOH 17  217 25  HOH HOH C . 
F 2 HOH 18  218 414 HOH HOH C . 
F 2 HOH 19  219 264 HOH HOH C . 
F 2 HOH 20  220 256 HOH HOH C . 
F 2 HOH 21  221 234 HOH HOH C . 
F 2 HOH 22  222 458 HOH HOH C . 
F 2 HOH 23  223 122 HOH HOH C . 
F 2 HOH 24  224 204 HOH HOH C . 
F 2 HOH 25  225 138 HOH HOH C . 
F 2 HOH 26  226 229 HOH HOH C . 
F 2 HOH 27  227 140 HOH HOH C . 
F 2 HOH 28  228 246 HOH HOH C . 
F 2 HOH 29  229 227 HOH HOH C . 
F 2 HOH 30  230 99  HOH HOH C . 
F 2 HOH 31  231 143 HOH HOH C . 
F 2 HOH 32  232 224 HOH HOH C . 
F 2 HOH 33  233 18  HOH HOH C . 
F 2 HOH 34  234 137 HOH HOH C . 
F 2 HOH 35  235 156 HOH HOH C . 
F 2 HOH 36  236 102 HOH HOH C . 
F 2 HOH 37  237 88  HOH HOH C . 
F 2 HOH 38  238 355 HOH HOH C . 
F 2 HOH 39  239 162 HOH HOH C . 
F 2 HOH 40  240 117 HOH HOH C . 
F 2 HOH 41  241 14  HOH HOH C . 
F 2 HOH 42  242 72  HOH HOH C . 
F 2 HOH 43  243 260 HOH HOH C . 
F 2 HOH 44  244 423 HOH HOH C . 
F 2 HOH 45  245 417 HOH HOH C . 
F 2 HOH 46  246 97  HOH HOH C . 
F 2 HOH 47  247 349 HOH HOH C . 
F 2 HOH 48  248 11  HOH HOH C . 
F 2 HOH 49  249 177 HOH HOH C . 
F 2 HOH 50  250 105 HOH HOH C . 
F 2 HOH 51  251 315 HOH HOH C . 
F 2 HOH 52  252 57  HOH HOH C . 
F 2 HOH 53  253 20  HOH HOH C . 
F 2 HOH 54  254 8   HOH HOH C . 
F 2 HOH 55  255 338 HOH HOH C . 
F 2 HOH 56  256 135 HOH HOH C . 
F 2 HOH 57  257 182 HOH HOH C . 
F 2 HOH 58  258 309 HOH HOH C . 
F 2 HOH 59  259 304 HOH HOH C . 
F 2 HOH 60  260 109 HOH HOH C . 
F 2 HOH 61  261 152 HOH HOH C . 
F 2 HOH 62  262 457 HOH HOH C . 
F 2 HOH 63  263 48  HOH HOH C . 
F 2 HOH 64  264 371 HOH HOH C . 
F 2 HOH 65  265 151 HOH HOH C . 
F 2 HOH 66  266 172 HOH HOH C . 
F 2 HOH 67  267 50  HOH HOH C . 
F 2 HOH 68  268 146 HOH HOH C . 
F 2 HOH 69  269 348 HOH HOH C . 
F 2 HOH 70  270 131 HOH HOH C . 
F 2 HOH 71  271 36  HOH HOH C . 
F 2 HOH 72  272 249 HOH HOH C . 
F 2 HOH 73  273 208 HOH HOH C . 
F 2 HOH 74  274 198 HOH HOH C . 
F 2 HOH 75  275 111 HOH HOH C . 
F 2 HOH 76  276 150 HOH HOH C . 
F 2 HOH 77  277 359 HOH HOH C . 
F 2 HOH 78  278 75  HOH HOH C . 
F 2 HOH 79  279 481 HOH HOH C . 
F 2 HOH 80  280 432 HOH HOH C . 
F 2 HOH 81  281 252 HOH HOH C . 
F 2 HOH 82  282 128 HOH HOH C . 
F 2 HOH 83  283 231 HOH HOH C . 
F 2 HOH 84  284 345 HOH HOH C . 
F 2 HOH 85  285 297 HOH HOH C . 
F 2 HOH 86  286 139 HOH HOH C . 
F 2 HOH 87  287 169 HOH HOH C . 
F 2 HOH 88  288 80  HOH HOH C . 
F 2 HOH 89  289 24  HOH HOH C . 
F 2 HOH 90  290 286 HOH HOH C . 
F 2 HOH 91  291 108 HOH HOH C . 
F 2 HOH 92  292 66  HOH HOH C . 
F 2 HOH 93  293 243 HOH HOH C . 
F 2 HOH 94  294 289 HOH HOH C . 
F 2 HOH 95  295 30  HOH HOH C . 
F 2 HOH 96  296 443 HOH HOH C . 
F 2 HOH 97  297 436 HOH HOH C . 
F 2 HOH 98  298 186 HOH HOH C . 
F 2 HOH 99  299 201 HOH HOH C . 
F 2 HOH 100 300 293 HOH HOH C . 
F 2 HOH 101 301 480 HOH HOH C . 
F 2 HOH 102 302 52  HOH HOH C . 
F 2 HOH 103 303 324 HOH HOH C . 
F 2 HOH 104 304 330 HOH HOH C . 
F 2 HOH 105 305 468 HOH HOH C . 
F 2 HOH 106 306 485 HOH HOH C . 
F 2 HOH 107 307 398 HOH HOH C . 
F 2 HOH 108 308 433 HOH HOH C . 
F 2 HOH 109 309 422 HOH HOH C . 
F 2 HOH 110 310 408 HOH HOH C . 
F 2 HOH 111 311 383 HOH HOH C . 
F 2 HOH 112 312 94  HOH HOH C . 
F 2 HOH 113 313 486 HOH HOH C . 
F 2 HOH 114 314 96  HOH HOH C . 
F 2 HOH 115 315 470 HOH HOH C . 
F 2 HOH 116 316 85  HOH HOH C . 
F 2 HOH 117 317 437 HOH HOH C . 
F 2 HOH 118 318 389 HOH HOH C . 
F 2 HOH 119 319 258 HOH HOH C . 
F 2 HOH 120 320 268 HOH HOH C . 
F 2 HOH 121 321 196 HOH HOH C . 
F 2 HOH 122 322 460 HOH HOH C . 
F 2 HOH 123 323 37  HOH HOH C . 
F 2 HOH 124 324 329 HOH HOH C . 
F 2 HOH 125 325 394 HOH HOH C . 
F 2 HOH 126 326 228 HOH HOH C . 
F 2 HOH 127 327 339 HOH HOH C . 
F 2 HOH 128 328 303 HOH HOH C . 
F 2 HOH 129 329 471 HOH HOH C . 
F 2 HOH 130 330 283 HOH HOH C . 
F 2 HOH 131 331 362 HOH HOH C . 
F 2 HOH 132 332 335 HOH HOH C . 
F 2 HOH 133 333 210 HOH HOH C . 
F 2 HOH 134 334 484 HOH HOH C . 
F 2 HOH 135 335 267 HOH HOH C . 
F 2 HOH 136 336 255 HOH HOH C . 
F 2 HOH 137 337 420 HOH HOH C . 
F 2 HOH 138 338 477 HOH HOH C . 
F 2 HOH 139 339 419 HOH HOH C . 
F 2 HOH 140 340 376 HOH HOH C . 
F 2 HOH 141 341 428 HOH HOH C . 
F 2 HOH 142 342 402 HOH HOH C . 
F 2 HOH 143 343 101 HOH HOH C . 
F 2 HOH 144 344 385 HOH HOH C . 
F 2 HOH 145 345 240 HOH HOH C . 
F 2 HOH 146 346 391 HOH HOH C . 
F 2 HOH 147 347 409 HOH HOH C . 
F 2 HOH 148 348 469 HOH HOH C . 
F 2 HOH 149 349 364 HOH HOH C . 
F 2 HOH 150 350 318 HOH HOH C . 
F 2 HOH 151 351 431 HOH HOH C . 
F 2 HOH 152 352 466 HOH HOH C . 
F 2 HOH 153 353 410 HOH HOH C . 
F 2 HOH 154 354 296 HOH HOH C . 
F 2 HOH 155 355 215 HOH HOH C . 
F 2 HOH 156 356 347 HOH HOH C . 
F 2 HOH 157 357 344 HOH HOH C . 
F 2 HOH 158 358 459 HOH HOH C . 
F 2 HOH 159 359 360 HOH HOH C . 
F 2 HOH 160 360 239 HOH HOH C . 
F 2 HOH 161 361 257 HOH HOH C . 
F 2 HOH 162 362 343 HOH HOH C . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? 1.20_4459 1 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? 1.20_4459 2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? HKL-3000 ? ? ? .         3 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? HKL-3000 ? ? ? .         4 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? .         5 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  120.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9L2Q 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     108.714 
_cell.length_a_esd                 ? 
_cell.length_b                     108.714 
_cell.length_b_esd                 ? 
_cell.length_c                     187.651 
_cell.length_c_esd                 ? 
_cell.volume                       1920668.729 
_cell.volume_esd                   ? 
_cell.Z_PDB                        36 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9L2Q 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                182 
_symmetry.space_group_name_Hall            'P 6c 2c' 
_symmetry.space_group_name_H-M             'P 63 2 2' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9L2Q 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             4.44 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          72.30 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'LIQUID DIFFUSION' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    'PEG 8000,HEPES/ Sodkum hydroxide' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            291.15 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     80 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS3 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2020-11-29 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.979 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRF BEAMLINE BL19U1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.979 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL19U1 
_diffrn_source.pdbx_synchrotron_site       SSRF 
# 
_reflns.B_iso_Wilson_estimate                          27.13 
_reflns.entry_id                                       9L2Q 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.054 
_reflns.d_resolution_low                               54.36 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     33956 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           81.65 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                1.9 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          34.94 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   1 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.054 
_reflns_shell.d_res_low                                     2.218 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             34003 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.846 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               31.42 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9L2Q 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.054 
_refine.ls_d_res_low                             54.36 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     33949 
_refine.ls_number_reflns_R_free                  3660 
_refine.ls_number_reflns_R_work                  59160 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    81.19 
_refine.ls_percent_reflns_R_free                 5.83 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1880 
_refine.ls_R_factor_R_free                       0.2228 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1859 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          SAD 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 24.9948 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.2165 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.054 
_refine_hist.d_res_low                        54.36 
_refine_hist.number_atoms_solvent             489 
_refine_hist.number_atoms_total               2973 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        2484 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         0 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0065 ? 2526 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.7735 ? 3411 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0433 ? 390  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0056 ? 435  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 4.9039 ? 342  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.054 2.08  . . 69  1139 40.94 . . . . 0.2744 . . . . . . . . . . . 0.2519 
'X-RAY DIFFRACTION' 2.08  2.11  . . 76  1213 43.26 . . . . 0.2518 . . . . . . . . . . . 0.2327 
'X-RAY DIFFRACTION' 2.11  2.14  . . 80  1276 45.97 . . . . 0.2241 . . . . . . . . . . . 0.3043 
'X-RAY DIFFRACTION' 2.14  2.17  . . 86  1395 49.10 . . . . 0.2238 . . . . . . . . . . . 0.2994 
'X-RAY DIFFRACTION' 2.17  2.21  . . 89  1431 51.70 . . . . 0.2101 . . . . . . . . . . . 0.2895 
'X-RAY DIFFRACTION' 2.21  2.24  . . 99  1544 55.26 . . . . 0.2103 . . . . . . . . . . . 0.2324 
'X-RAY DIFFRACTION' 2.24  2.28  . . 102 1662 59.55 . . . . 0.2098 . . . . . . . . . . . 0.2721 
'X-RAY DIFFRACTION' 2.28  2.32  . . 109 1767 62.93 . . . . 0.2006 . . . . . . . . . . . 0.2577 
'X-RAY DIFFRACTION' 2.32  2.37  . . 118 1915 68.13 . . . . 0.2048 . . . . . . . . . . . 0.2502 
'X-RAY DIFFRACTION' 2.37  2.42  . . 132 2088 73.83 . . . . 0.2065 . . . . . . . . . . . 0.2036 
'X-RAY DIFFRACTION' 2.42  2.47  . . 136 2211 79.72 . . . . 0.1961 . . . . . . . . . . . 0.2663 
'X-RAY DIFFRACTION' 2.47  2.53  . . 159 2483 88.45 . . . . 0.2064 . . . . . . . . . . . 0.2298 
'X-RAY DIFFRACTION' 2.53  2.59  . . 161 2726 96.72 . . . . 0.1997 . . . . . . . . . . . 0.2297 
'X-RAY DIFFRACTION' 2.59  2.66  . . 166 2768 99.26 . . . . 0.2003 . . . . . . . . . . . 0.2715 
'X-RAY DIFFRACTION' 2.66  2.74  . . 172 2775 99.53 . . . . 0.2063 . . . . . . . . . . . 0.2653 
'X-RAY DIFFRACTION' 2.74  2.82  . . 171 2778 99.46 . . . . 0.2091 . . . . . . . . . . . 0.2483 
'X-RAY DIFFRACTION' 2.82  2.93  . . 171 2811 99.60 . . . . 0.2074 . . . . . . . . . . . 0.2405 
'X-RAY DIFFRACTION' 2.93  3.04  . . 174 2791 99.80 . . . . 0.2199 . . . . . . . . . . . 0.2328 
'X-RAY DIFFRACTION' 3.04  3.18  . . 173 2798 99.73 . . . . 0.1916 . . . . . . . . . . . 0.2781 
'X-RAY DIFFRACTION' 3.18  3.35  . . 176 2782 99.86 . . . . 0.1925 . . . . . . . . . . . 0.2310 
'X-RAY DIFFRACTION' 3.35  3.56  . . 180 2812 99.87 . . . . 0.1694 . . . . . . . . . . . 0.1881 
'X-RAY DIFFRACTION' 3.56  3.83  . . 176 2793 99.90 . . . . 0.1522 . . . . . . . . . . . 0.1840 
'X-RAY DIFFRACTION' 3.83  4.22  . . 173 2796 99.76 . . . . 0.1417 . . . . . . . . . . . 0.1739 
'X-RAY DIFFRACTION' 4.22  4.83  . . 173 2808 99.80 . . . . 0.1358 . . . . . . . . . . . 0.1609 
'X-RAY DIFFRACTION' 4.83  6.08  . . 173 2789 99.73 . . . . 0.2066 . . . . . . . . . . . 0.2512 
'X-RAY DIFFRACTION' 6.08  54.36 . . 166 2809 99.30 . . . . 0.1969 . . . . . . . . . . . 0.2308 
# 
_struct.entry_id                     9L2Q 
_struct.title                        'Crystal structure of anti-CRISPR protein AcrIE7' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9L2Q 
_struct_keywords.text            'hypothetical antiviral protein, ANTIVIRAL PROTEIN' 
_struct_keywords.pdbx_keywords   'ANTIVIRAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 2 ? 
E N N 2 ? 
F N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    PDB 
_struct_ref.db_code                    9L2Q 
_struct_ref.pdbx_db_accession          9L2Q 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   ? 
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9L2Q A 1 ? 107 ? 9L2Q 0 ? 106 ? 0 106 
2 1 9L2Q B 1 ? 107 ? 9L2Q 0 ? 106 ? 0 106 
3 1 9L2Q C 1 ? 107 ? 9L2Q 0 ? 106 ? 0 106 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_and_software_defined_assembly PISA hexameric 6 
2 author_and_software_defined_assembly PISA hexameric 6 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 7490  ? 
1 MORE         -58   ? 
1 'SSA (A^2)'  29800 ? 
2 'ABSA (A^2)' 7560  ? 
2 MORE         -61   ? 
2 'SSA (A^2)'  30050 ? 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1,2,3       A,B,D,E 
2 1,2,3,4,5,6 C,F     
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
1 'identity operation'         1_555  x,y,z           1.0000000000  0.0000000000  0.0000000000 0.0000000000    0.0000000000  
1.0000000000  0.0000000000 0.0000000000  0.0000000000 0.0000000000 1.0000000000  0.0000000000  
2 'crystal symmetry operation' 2_565  -y,x-y+1,z      -0.5000000000 -0.8660254038 0.0000000000 -54.3570000000  0.8660254038  
-0.5000000000 0.0000000000 94.1490857470 0.0000000000 0.0000000000 1.0000000000  0.0000000000  
3 'crystal symmetry operation' 3_455  -x+y-1,-x,z     -0.5000000000 0.8660254038  0.0000000000 -108.7140000000 -0.8660254038 
-0.5000000000 0.0000000000 0.0000000000  0.0000000000 0.0000000000 1.0000000000  0.0000000000  
4 'crystal symmetry operation' 10_555 -y,-x,-z+1/2    0.5000000000  -0.8660254038 0.0000000000 0.0000000000    -0.8660254038 
-0.5000000000 0.0000000000 0.0000000000  0.0000000000 0.0000000000 -1.0000000000 93.8255000000 
5 'crystal symmetry operation' 11_455 -x+y-1,y,-z+1/2 -1.0000000000 0.0000000000  0.0000000000 -108.7140000000 0.0000000000  
1.0000000000  0.0000000000 0.0000000000  0.0000000000 0.0000000000 -1.0000000000 93.8255000000 
6 'crystal symmetry operation' 12_565 x,x-y+1,-z+1/2  0.5000000000  0.8660254038  0.0000000000 -54.3570000000  0.8660254038  
-0.5000000000 0.0000000000 94.1490857470 0.0000000000 0.0000000000 -1.0000000000 93.8255000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 5  ? ALA A 25  ? SER A 4  ALA A 24  1 ? 21 
HELX_P HELX_P2  AA2 VAL A 30 ? ILE A 40  ? VAL A 29 ILE A 39  1 ? 11 
HELX_P HELX_P3  AA3 ASP A 42 ? ASN A 49  ? ASP A 41 ASN A 48  1 ? 8  
HELX_P HELX_P4  AA4 GLY A 59 ? SER A 67  ? GLY A 58 SER A 66  1 ? 9  
HELX_P HELX_P5  AA5 PRO A 68 ? ASN A 70  ? PRO A 67 ASN A 69  5 ? 3  
HELX_P HELX_P6  AA6 SER A 71 ? ARG A 76  ? SER A 70 ARG A 75  1 ? 6  
HELX_P HELX_P7  AA7 ARG A 77 ? SER A 79  ? ARG A 76 SER A 78  5 ? 3  
HELX_P HELX_P8  AA8 GLY A 84 ? GLU A 86  ? GLY A 83 GLU A 85  5 ? 3  
HELX_P HELX_P9  AA9 GLU A 87 ? GLU A 105 ? GLU A 86 GLU A 104 1 ? 19 
HELX_P HELX_P10 AB1 SER B 5  ? ALA B 25  ? SER B 4  ALA B 24  1 ? 21 
HELX_P HELX_P11 AB2 VAL B 30 ? ILE B 40  ? VAL B 29 ILE B 39  1 ? 11 
HELX_P HELX_P12 AB3 ASP B 42 ? ASN B 49  ? ASP B 41 ASN B 48  1 ? 8  
HELX_P HELX_P13 AB4 GLY B 59 ? SER B 67  ? GLY B 58 SER B 66  1 ? 9  
HELX_P HELX_P14 AB5 PRO B 68 ? ASN B 70  ? PRO B 67 ASN B 69  5 ? 3  
HELX_P HELX_P15 AB6 SER B 71 ? ARG B 76  ? SER B 70 ARG B 75  1 ? 6  
HELX_P HELX_P16 AB7 ARG B 77 ? SER B 79  ? ARG B 76 SER B 78  5 ? 3  
HELX_P HELX_P17 AB8 GLY B 84 ? GLU B 86  ? GLY B 83 GLU B 85  5 ? 3  
HELX_P HELX_P18 AB9 GLU B 87 ? GLU B 105 ? GLU B 86 GLU B 104 1 ? 19 
HELX_P HELX_P19 AC1 SER C 5  ? ALA C 25  ? SER C 4  ALA C 24  1 ? 21 
HELX_P HELX_P20 AC2 VAL C 30 ? ILE C 40  ? VAL C 29 ILE C 39  1 ? 11 
HELX_P HELX_P21 AC3 ASP C 42 ? ASN C 49  ? ASP C 41 ASN C 48  1 ? 8  
HELX_P HELX_P22 AC4 GLY C 59 ? SER C 67  ? GLY C 58 SER C 66  1 ? 9  
HELX_P HELX_P23 AC5 PRO C 68 ? ASN C 70  ? PRO C 67 ASN C 69  5 ? 3  
HELX_P HELX_P24 AC6 SER C 71 ? ARG C 76  ? SER C 70 ARG C 75  1 ? 6  
HELX_P HELX_P25 AC7 ARG C 77 ? SER C 79  ? ARG C 76 SER C 78  5 ? 3  
HELX_P HELX_P26 AC8 GLY C 84 ? GLU C 86  ? GLY C 83 GLU C 85  5 ? 3  
HELX_P HELX_P27 AC9 GLU C 87 ? GLU C 105 ? GLU C 86 GLU C 104 1 ? 19 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_pdbx_entry_details.entry_id                   9L2Q 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 O A HOH 307 ? ? O A HOH 316 ? ? 2.06 
2 1 O A GLU 104 ? ? O A HOH 201 ? ? 2.10 
3 1 O B GLU 104 ? ? O B HOH 201 ? ? 2.14 
4 1 O B HOH 297 ? ? O B HOH 337 ? ? 2.17 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 CYS A 80 ? ? -156.35 44.25 
2 1 CYS B 80 ? ? -140.56 43.65 
3 1 CYS C 80 ? ? -149.32 43.37 
# 
loop_
_pdbx_struct_special_symmetry.id 
_pdbx_struct_special_symmetry.PDB_model_num 
_pdbx_struct_special_symmetry.auth_asym_id 
_pdbx_struct_special_symmetry.auth_comp_id 
_pdbx_struct_special_symmetry.auth_seq_id 
_pdbx_struct_special_symmetry.PDB_ins_code 
_pdbx_struct_special_symmetry.label_asym_id 
_pdbx_struct_special_symmetry.label_comp_id 
_pdbx_struct_special_symmetry.label_seq_id 
1 1 A HOH 369 ? D HOH . 
2 1 C HOH 262 ? F HOH . 
3 1 C HOH 327 ? F HOH . 
4 1 C HOH 355 ? F HOH . 
5 1 C HOH 356 ? F HOH . 
6 1 C HOH 361 ? F HOH . 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1  x,y,z         
2  x-y,x,z+1/2   
3  y,-x+y,z+1/2  
4  -y,x-y,z      
5  -x+y,-x,z     
6  x-y,-y,-z     
7  -x,-x+y,-z    
8  -x,-y,z+1/2   
9  y,x,-z        
10 -y,-x,-z+1/2  
11 -x+y,y,-z+1/2 
12 x,x-y,-z+1/2  
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 A ASP 105 ? A ASP 106 
2 1 Y 1 A GLU 106 ? A GLU 107 
3 1 Y 1 B ASP 105 ? B ASP 106 
4 1 Y 1 B GLU 106 ? B GLU 107 
5 1 Y 1 C ASP 105 ? C ASP 106 
6 1 Y 1 C GLU 106 ? C GLU 107 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
HOH O    O N N 158 
HOH H1   H N N 159 
HOH H2   H N N 160 
ILE N    N N N 161 
ILE CA   C N S 162 
ILE C    C N N 163 
ILE O    O N N 164 
ILE CB   C N S 165 
ILE CG1  C N N 166 
ILE CG2  C N N 167 
ILE CD1  C N N 168 
ILE OXT  O N N 169 
ILE H    H N N 170 
ILE H2   H N N 171 
ILE HA   H N N 172 
ILE HB   H N N 173 
ILE HG12 H N N 174 
ILE HG13 H N N 175 
ILE HG21 H N N 176 
ILE HG22 H N N 177 
ILE HG23 H N N 178 
ILE HD11 H N N 179 
ILE HD12 H N N 180 
ILE HD13 H N N 181 
ILE HXT  H N N 182 
LEU N    N N N 183 
LEU CA   C N S 184 
LEU C    C N N 185 
LEU O    O N N 186 
LEU CB   C N N 187 
LEU CG   C N N 188 
LEU CD1  C N N 189 
LEU CD2  C N N 190 
LEU OXT  O N N 191 
LEU H    H N N 192 
LEU H2   H N N 193 
LEU HA   H N N 194 
LEU HB2  H N N 195 
LEU HB3  H N N 196 
LEU HG   H N N 197 
LEU HD11 H N N 198 
LEU HD12 H N N 199 
LEU HD13 H N N 200 
LEU HD21 H N N 201 
LEU HD22 H N N 202 
LEU HD23 H N N 203 
LEU HXT  H N N 204 
LYS N    N N N 205 
LYS CA   C N S 206 
LYS C    C N N 207 
LYS O    O N N 208 
LYS CB   C N N 209 
LYS CG   C N N 210 
LYS CD   C N N 211 
LYS CE   C N N 212 
LYS NZ   N N N 213 
LYS OXT  O N N 214 
LYS H    H N N 215 
LYS H2   H N N 216 
LYS HA   H N N 217 
LYS HB2  H N N 218 
LYS HB3  H N N 219 
LYS HG2  H N N 220 
LYS HG3  H N N 221 
LYS HD2  H N N 222 
LYS HD3  H N N 223 
LYS HE2  H N N 224 
LYS HE3  H N N 225 
LYS HZ1  H N N 226 
LYS HZ2  H N N 227 
LYS HZ3  H N N 228 
LYS HXT  H N N 229 
MET N    N N N 230 
MET CA   C N S 231 
MET C    C N N 232 
MET O    O N N 233 
MET CB   C N N 234 
MET CG   C N N 235 
MET SD   S N N 236 
MET CE   C N N 237 
MET OXT  O N N 238 
MET H    H N N 239 
MET H2   H N N 240 
MET HA   H N N 241 
MET HB2  H N N 242 
MET HB3  H N N 243 
MET HG2  H N N 244 
MET HG3  H N N 245 
MET HE1  H N N 246 
MET HE2  H N N 247 
MET HE3  H N N 248 
MET HXT  H N N 249 
PHE N    N N N 250 
PHE CA   C N S 251 
PHE C    C N N 252 
PHE O    O N N 253 
PHE CB   C N N 254 
PHE CG   C Y N 255 
PHE CD1  C Y N 256 
PHE CD2  C Y N 257 
PHE CE1  C Y N 258 
PHE CE2  C Y N 259 
PHE CZ   C Y N 260 
PHE OXT  O N N 261 
PHE H    H N N 262 
PHE H2   H N N 263 
PHE HA   H N N 264 
PHE HB2  H N N 265 
PHE HB3  H N N 266 
PHE HD1  H N N 267 
PHE HD2  H N N 268 
PHE HE1  H N N 269 
PHE HE2  H N N 270 
PHE HZ   H N N 271 
PHE HXT  H N N 272 
PRO N    N N N 273 
PRO CA   C N S 274 
PRO C    C N N 275 
PRO O    O N N 276 
PRO CB   C N N 277 
PRO CG   C N N 278 
PRO CD   C N N 279 
PRO OXT  O N N 280 
PRO H    H N N 281 
PRO HA   H N N 282 
PRO HB2  H N N 283 
PRO HB3  H N N 284 
PRO HG2  H N N 285 
PRO HG3  H N N 286 
PRO HD2  H N N 287 
PRO HD3  H N N 288 
PRO HXT  H N N 289 
SER N    N N N 290 
SER CA   C N S 291 
SER C    C N N 292 
SER O    O N N 293 
SER CB   C N N 294 
SER OG   O N N 295 
SER OXT  O N N 296 
SER H    H N N 297 
SER H2   H N N 298 
SER HA   H N N 299 
SER HB2  H N N 300 
SER HB3  H N N 301 
SER HG   H N N 302 
SER HXT  H N N 303 
THR N    N N N 304 
THR CA   C N S 305 
THR C    C N N 306 
THR O    O N N 307 
THR CB   C N R 308 
THR OG1  O N N 309 
THR CG2  C N N 310 
THR OXT  O N N 311 
THR H    H N N 312 
THR H2   H N N 313 
THR HA   H N N 314 
THR HB   H N N 315 
THR HG1  H N N 316 
THR HG21 H N N 317 
THR HG22 H N N 318 
THR HG23 H N N 319 
THR HXT  H N N 320 
TRP N    N N N 321 
TRP CA   C N S 322 
TRP C    C N N 323 
TRP O    O N N 324 
TRP CB   C N N 325 
TRP CG   C Y N 326 
TRP CD1  C Y N 327 
TRP CD2  C Y N 328 
TRP NE1  N Y N 329 
TRP CE2  C Y N 330 
TRP CE3  C Y N 331 
TRP CZ2  C Y N 332 
TRP CZ3  C Y N 333 
TRP CH2  C Y N 334 
TRP OXT  O N N 335 
TRP H    H N N 336 
TRP H2   H N N 337 
TRP HA   H N N 338 
TRP HB2  H N N 339 
TRP HB3  H N N 340 
TRP HD1  H N N 341 
TRP HE1  H N N 342 
TRP HE3  H N N 343 
TRP HZ2  H N N 344 
TRP HZ3  H N N 345 
TRP HH2  H N N 346 
TRP HXT  H N N 347 
TYR N    N N N 348 
TYR CA   C N S 349 
TYR C    C N N 350 
TYR O    O N N 351 
TYR CB   C N N 352 
TYR CG   C Y N 353 
TYR CD1  C Y N 354 
TYR CD2  C Y N 355 
TYR CE1  C Y N 356 
TYR CE2  C Y N 357 
TYR CZ   C Y N 358 
TYR OH   O N N 359 
TYR OXT  O N N 360 
TYR H    H N N 361 
TYR H2   H N N 362 
TYR HA   H N N 363 
TYR HB2  H N N 364 
TYR HB3  H N N 365 
TYR HD1  H N N 366 
TYR HD2  H N N 367 
TYR HE1  H N N 368 
TYR HE2  H N N 369 
TYR HH   H N N 370 
TYR HXT  H N N 371 
VAL N    N N N 372 
VAL CA   C N S 373 
VAL C    C N N 374 
VAL O    O N N 375 
VAL CB   C N N 376 
VAL CG1  C N N 377 
VAL CG2  C N N 378 
VAL OXT  O N N 379 
VAL H    H N N 380 
VAL H2   H N N 381 
VAL HA   H N N 382 
VAL HB   H N N 383 
VAL HG11 H N N 384 
VAL HG12 H N N 385 
VAL HG13 H N N 386 
VAL HG21 H N N 387 
VAL HG22 H N N 388 
VAL HG23 H N N 389 
VAL HXT  H N N 390 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
PHE N   CA   sing N N 237 
PHE N   H    sing N N 238 
PHE N   H2   sing N N 239 
PHE CA  C    sing N N 240 
PHE CA  CB   sing N N 241 
PHE CA  HA   sing N N 242 
PHE C   O    doub N N 243 
PHE C   OXT  sing N N 244 
PHE CB  CG   sing N N 245 
PHE CB  HB2  sing N N 246 
PHE CB  HB3  sing N N 247 
PHE CG  CD1  doub Y N 248 
PHE CG  CD2  sing Y N 249 
PHE CD1 CE1  sing Y N 250 
PHE CD1 HD1  sing N N 251 
PHE CD2 CE2  doub Y N 252 
PHE CD2 HD2  sing N N 253 
PHE CE1 CZ   doub Y N 254 
PHE CE1 HE1  sing N N 255 
PHE CE2 CZ   sing Y N 256 
PHE CE2 HE2  sing N N 257 
PHE CZ  HZ   sing N N 258 
PHE OXT HXT  sing N N 259 
PRO N   CA   sing N N 260 
PRO N   CD   sing N N 261 
PRO N   H    sing N N 262 
PRO CA  C    sing N N 263 
PRO CA  CB   sing N N 264 
PRO CA  HA   sing N N 265 
PRO C   O    doub N N 266 
PRO C   OXT  sing N N 267 
PRO CB  CG   sing N N 268 
PRO CB  HB2  sing N N 269 
PRO CB  HB3  sing N N 270 
PRO CG  CD   sing N N 271 
PRO CG  HG2  sing N N 272 
PRO CG  HG3  sing N N 273 
PRO CD  HD2  sing N N 274 
PRO CD  HD3  sing N N 275 
PRO OXT HXT  sing N N 276 
SER N   CA   sing N N 277 
SER N   H    sing N N 278 
SER N   H2   sing N N 279 
SER CA  C    sing N N 280 
SER CA  CB   sing N N 281 
SER CA  HA   sing N N 282 
SER C   O    doub N N 283 
SER C   OXT  sing N N 284 
SER CB  OG   sing N N 285 
SER CB  HB2  sing N N 286 
SER CB  HB3  sing N N 287 
SER OG  HG   sing N N 288 
SER OXT HXT  sing N N 289 
THR N   CA   sing N N 290 
THR N   H    sing N N 291 
THR N   H2   sing N N 292 
THR CA  C    sing N N 293 
THR CA  CB   sing N N 294 
THR CA  HA   sing N N 295 
THR C   O    doub N N 296 
THR C   OXT  sing N N 297 
THR CB  OG1  sing N N 298 
THR CB  CG2  sing N N 299 
THR CB  HB   sing N N 300 
THR OG1 HG1  sing N N 301 
THR CG2 HG21 sing N N 302 
THR CG2 HG22 sing N N 303 
THR CG2 HG23 sing N N 304 
THR OXT HXT  sing N N 305 
TRP N   CA   sing N N 306 
TRP N   H    sing N N 307 
TRP N   H2   sing N N 308 
TRP CA  C    sing N N 309 
TRP CA  CB   sing N N 310 
TRP CA  HA   sing N N 311 
TRP C   O    doub N N 312 
TRP C   OXT  sing N N 313 
TRP CB  CG   sing N N 314 
TRP CB  HB2  sing N N 315 
TRP CB  HB3  sing N N 316 
TRP CG  CD1  doub Y N 317 
TRP CG  CD2  sing Y N 318 
TRP CD1 NE1  sing Y N 319 
TRP CD1 HD1  sing N N 320 
TRP CD2 CE2  doub Y N 321 
TRP CD2 CE3  sing Y N 322 
TRP NE1 CE2  sing Y N 323 
TRP NE1 HE1  sing N N 324 
TRP CE2 CZ2  sing Y N 325 
TRP CE3 CZ3  doub Y N 326 
TRP CE3 HE3  sing N N 327 
TRP CZ2 CH2  doub Y N 328 
TRP CZ2 HZ2  sing N N 329 
TRP CZ3 CH2  sing Y N 330 
TRP CZ3 HZ3  sing N N 331 
TRP CH2 HH2  sing N N 332 
TRP OXT HXT  sing N N 333 
TYR N   CA   sing N N 334 
TYR N   H    sing N N 335 
TYR N   H2   sing N N 336 
TYR CA  C    sing N N 337 
TYR CA  CB   sing N N 338 
TYR CA  HA   sing N N 339 
TYR C   O    doub N N 340 
TYR C   OXT  sing N N 341 
TYR CB  CG   sing N N 342 
TYR CB  HB2  sing N N 343 
TYR CB  HB3  sing N N 344 
TYR CG  CD1  doub Y N 345 
TYR CG  CD2  sing Y N 346 
TYR CD1 CE1  sing Y N 347 
TYR CD1 HD1  sing N N 348 
TYR CD2 CE2  doub Y N 349 
TYR CD2 HD2  sing N N 350 
TYR CE1 CZ   doub Y N 351 
TYR CE1 HE1  sing N N 352 
TYR CE2 CZ   sing Y N 353 
TYR CE2 HE2  sing N N 354 
TYR CZ  OH   sing N N 355 
TYR OH  HH   sing N N 356 
TYR OXT HXT  sing N N 357 
VAL N   CA   sing N N 358 
VAL N   H    sing N N 359 
VAL N   H2   sing N N 360 
VAL CA  C    sing N N 361 
VAL CA  CB   sing N N 362 
VAL CA  HA   sing N N 363 
VAL C   O    doub N N 364 
VAL C   OXT  sing N N 365 
VAL CB  CG1  sing N N 366 
VAL CB  CG2  sing N N 367 
VAL CB  HB   sing N N 368 
VAL CG1 HG11 sing N N 369 
VAL CG1 HG12 sing N N 370 
VAL CG1 HG13 sing N N 371 
VAL CG2 HG21 sing N N 372 
VAL CG2 HG22 sing N N 373 
VAL CG2 HG23 sing N N 374 
VAL OXT HXT  sing N N 375 
# 
_pdbx_audit_support.funding_organization   'Other government' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_space_group.name_H-M_alt     'P 63 2 2' 
_space_group.name_Hall        'P 6c 2c' 
_space_group.IT_number        182 
_space_group.crystal_system   hexagonal 
_space_group.id               1 
# 
_atom_sites.entry_id                    9L2Q 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.009198 
_atom_sites.fract_transf_matrix[1][2]   0.005311 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.010621 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.005329 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . GLY A 1 1   ? -31.24110 38.76963 -33.34048 1.000 59.09744 ? 0   GLY A N   1 
ATOM   2    C CA  . GLY A 1 1   ? -32.07798 39.08135 -32.20588 1.000 44.61378 ? 0   GLY A CA  1 
ATOM   3    C C   . GLY A 1 1   ? -31.23722 39.41412 -30.99791 1.000 44.09073 ? 0   GLY A C   1 
ATOM   4    O O   . GLY A 1 1   ? -31.32174 40.53788 -30.49034 1.000 48.98073 ? 0   GLY A O   1 
ATOM   5    N N   . MET A 1 2   ? -30.42262 38.46068 -30.54112 1.000 40.79290 ? 1   MET A N   1 
ATOM   6    C CA  . MET A 1 2   ? -29.73311 38.62643 -29.26539 1.000 37.97419 ? 1   MET A CA  1 
ATOM   7    C C   . MET A 1 2   ? -28.62225 39.67142 -29.36187 1.000 35.21502 ? 1   MET A C   1 
ATOM   8    O O   . MET A 1 2   ? -27.70581 39.54379 -30.17975 1.000 32.38058 ? 1   MET A O   1 
ATOM   9    C CB  . MET A 1 2   ? -29.14252 37.30339 -28.79571 1.000 43.15073 ? 1   MET A CB  1 
ATOM   10   C CG  . MET A 1 2   ? -28.59433 37.41949 -27.37122 1.000 34.95972 ? 1   MET A CG  1 
ATOM   11   S SD  . MET A 1 2   ? -28.05874 35.90766 -26.57694 1.000 60.50073 ? 1   MET A SD  1 
ATOM   12   C CE  . MET A 1 2   ? -29.59741 34.99450 -26.45157 1.000 48.41073 ? 1   MET A CE  1 
ATOM   13   N N   . ILE A 1 3   ? -28.67788 40.68686 -28.47024 1.000 30.13915 ? 2   ILE A N   1 
ATOM   14   C CA  . ILE A 1 3   ? -27.71587 41.78254 -28.44027 1.000 28.40469 ? 2   ILE A CA  1 
ATOM   15   C C   . ILE A 1 3   ? -26.54331 41.38776 -27.54797 1.000 32.89089 ? 2   ILE A C   1 
ATOM   16   O O   . ILE A 1 3   ? -26.68857 40.64350 -26.57434 1.000 30.74785 ? 2   ILE A O   1 
ATOM   17   C CB  . ILE A 1 3   ? -28.38441 43.09967 -27.97528 1.000 31.71784 ? 2   ILE A CB  1 
ATOM   18   C CG1 . ILE A 1 3   ? -28.79874 43.04549 -26.51467 1.000 30.10235 ? 2   ILE A CG1 1 
ATOM   19   C CG2 . ILE A 1 3   ? -29.59454 43.41193 -28.83189 1.000 33.40813 ? 2   ILE A CG2 1 
ATOM   20   C CD1 . ILE A 1 3   ? -29.30211 44.38000 -25.95915 1.000 34.35935 ? 2   ILE A CD1 1 
ATOM   21   N N   . GLY A 1 4   ? -25.36414 41.91663 -27.86444 1.000 29.65484 ? 3   GLY A N   1 
ATOM   22   C CA  . GLY A 1 4   ? -24.13626 41.55863 -27.18485 1.000 30.33213 ? 3   GLY A CA  1 
ATOM   23   C C   . GLY A 1 4   ? -23.00550 41.30491 -28.16409 1.000 31.66873 ? 3   GLY A C   1 
ATOM   24   O O   . GLY A 1 4   ? -23.23862 41.20581 -29.37062 1.000 25.75699 ? 3   GLY A O   1 
ATOM   25   N N   . SER A 1 5   ? -21.77732 41.21033 -27.66173 1.000 29.82711 ? 4   SER A N   1 
ATOM   26   C CA  . SER A 1 5   ? -20.64790 40.82992 -28.49741 1.000 31.19328 ? 4   SER A CA  1 
ATOM   27   C C   . SER A 1 5   ? -20.81774 39.38420 -28.97243 1.000 31.67928 ? 4   SER A C   1 
ATOM   28   O O   . SER A 1 5   ? -21.66102 38.63330 -28.47452 1.000 26.48205 ? 4   SER A O   1 
ATOM   29   C CB  . SER A 1 5   ? -19.33838 40.98860 -27.72702 1.000 29.37558 ? 4   SER A CB  1 
ATOM   30   O OG  . SER A 1 5   ? -19.16028 39.84643 -26.90198 1.000 25.59376 ? 4   SER A OG  1 
ATOM   31   N N   . GLU A 1 6   ? -19.99380 38.98110 -29.94565 1.000 28.88703 ? 5   GLU A N   1 
ATOM   32   C CA  . GLU A 1 6   ? -20.15993 37.64912 -30.52624 1.000 30.54336 ? 5   GLU A CA  1 
ATOM   33   C C   . GLU A 1 6   ? -19.88109 36.57353 -29.48170 1.000 30.24503 ? 5   GLU A C   1 
ATOM   34   O O   . GLU A 1 6   ? -20.61591 35.58050 -29.38220 1.000 28.47948 ? 5   GLU A O   1 
ATOM   35   C CB  . GLU A 1 6   ? -19.25041 37.48182 -31.75602 1.000 36.59748 ? 5   GLU A CB  1 
ATOM   36   C CG  . GLU A 1 6   ? -18.84937 36.04295 -32.04520 1.000 44.17709 ? 5   GLU A CG  1 
ATOM   37   C CD  . GLU A 1 6   ? -17.73341 35.92778 -33.08548 1.000 56.83260 ? 5   GLU A CD  1 
ATOM   38   O OE1 . GLU A 1 6   ? -16.83108 36.80039 -33.10854 1.000 54.95512 ? 5   GLU A OE1 1 
ATOM   39   O OE2 . GLU A 1 6   ? -17.76349 34.96416 -33.88807 1.000 61.66875 ? 5   GLU A OE2 1 
ATOM   40   N N   . LYS A 1 7   ? -18.84073 36.76957 -28.66438 1.000 26.12313 ? 6   LYS A N   1 
ATOM   41   C CA  . LYS A 1 7   ? -18.56266 35.82731 -27.57639 1.000 27.79073 ? 6   LYS A CA  1 
ATOM   42   C C   . LYS A 1 7   ? -19.67002 35.79676 -26.51814 1.000 29.66078 ? 6   LYS A C   1 
ATOM   43   O O   . LYS A 1 7   ? -19.99535 34.72254 -25.98620 1.000 28.25530 ? 6   LYS A O   1 
ATOM   44   C CB  . LYS A 1 7   ? -17.21092 36.12961 -26.92695 1.000 31.28693 ? 6   LYS A CB  1 
ATOM   45   C CG  . LYS A 1 7   ? -16.10517 36.20999 -27.89573 1.000 41.39756 ? 6   LYS A CG  1 
ATOM   46   C CD  . LYS A 1 7   ? -15.50389 34.87720 -28.05921 1.000 46.07073 ? 6   LYS A CD  1 
ATOM   47   C CE  . LYS A 1 7   ? -14.10955 35.02214 -28.62425 1.000 47.09530 ? 6   LYS A CE  1 
ATOM   48   N NZ  . LYS A 1 7   ? -13.59632 33.70070 -29.08677 1.000 49.75749 ? 6   LYS A NZ  1 
ATOM   49   N N   . GLN A 1 8   ? -20.20920 36.95631 -26.13758 1.000 26.27128 ? 7   GLN A N   1 
ATOM   50   C CA  . GLN A 1 8   ? -21.26573 36.95456 -25.13011 1.000 29.00932 ? 7   GLN A CA  1 
ATOM   51   C C   . GLN A 1 8   ? -22.48718 36.22218 -25.64940 1.000 25.91674 ? 7   GLN A C   1 
ATOM   52   O O   . GLN A 1 8   ? -23.08184 35.40910 -24.93819 1.000 29.35836 ? 7   GLN A O   1 
ATOM   53   C CB  . GLN A 1 8   ? -21.63306 38.37990 -24.72483 1.000 30.03738 ? 7   GLN A CB  1 
ATOM   54   C CG  . GLN A 1 8   ? -20.45771 39.22931 -24.30205 1.000 26.68634 ? 7   GLN A CG  1 
ATOM   55   C CD  . GLN A 1 8   ? -20.88353 40.63571 -23.96061 1.000 32.17528 ? 7   GLN A CD  1 
ATOM   56   O OE1 . GLN A 1 8   ? -21.42904 41.35887 -24.80276 1.000 27.96554 ? 7   GLN A OE1 1 
ATOM   57   N NE2 . GLN A 1 8   ? -20.63001 41.04140 -22.72563 1.000 35.91226 ? 7   GLN A NE2 1 
ATOM   58   N N   . VAL A 1 9   ? -22.86156 36.48842 -26.90574 1.000 28.71164 ? 8   VAL A N   1 
ATOM   59   C CA  . VAL A 1 9   ? -24.02469 35.83832 -27.50293 1.000 27.34482 ? 8   VAL A CA  1 
ATOM   60   C C   . VAL A 1 9   ? -23.83787 34.32812 -27.52360 1.000 29.82453 ? 8   VAL A C   1 
ATOM   61   O O   . VAL A 1 9   ? -24.73801 33.57216 -27.14292 1.000 25.20234 ? 8   VAL A O   1 
ATOM   62   C CB  . VAL A 1 9   ? -24.28448 36.39688 -28.90933 1.000 28.99521 ? 8   VAL A CB  1 
ATOM   63   C CG1 . VAL A 1 9   ? -25.24487 35.49521 -29.66472 1.000 29.70059 ? 8   VAL A CG1 1 
ATOM   64   C CG2 . VAL A 1 9   ? -24.81948 37.81931 -28.80980 1.000 32.68700 ? 8   VAL A CG2 1 
ATOM   65   N N   . ASN A 1 10  ? -22.65279 33.86718 -27.93975 1.000 29.50263 ? 9   ASN A N   1 
ATOM   66   C CA  . ASN A 1 10  ? -22.38867 32.43207 -27.97761 1.000 28.06698 ? 9   ASN A CA  1 
ATOM   67   C C   . ASN A 1 10  ? -22.48161 31.81747 -26.58653 1.000 29.85655 ? 9   ASN A C   1 
ATOM   68   O O   . ASN A 1 10  ? -23.09822 30.75975 -26.40844 1.000 27.81416 ? 9   ASN A O   1 
ATOM   69   C CB  . ASN A 1 10  ? -21.01950 32.16304 -28.60350 1.000 30.03496 ? 9   ASN A CB  1 
ATOM   70   C CG  . ASN A 1 10  ? -21.06013 32.21969 -30.11902 1.000 44.65927 ? 9   ASN A CG  1 
ATOM   71   O OD1 . ASN A 1 10  ? -20.02060 32.30583 -30.78264 1.000 54.72764 ? 9   ASN A OD1 1 
ATOM   72   N ND2 . ASN A 1 10  ? -22.27432 32.18653 -30.68187 1.000 46.57197 ? 9   ASN A ND2 1 
ATOM   73   N N   . TRP A 1 11  ? -21.87180 32.46308 -25.58415 1.000 24.34347 ? 10  TRP A N   1 
ATOM   74   C CA  . TRP A 1 11  ? -21.96582 31.95395 -24.21877 1.000 25.66667 ? 10  TRP A CA  1 
ATOM   75   C C   . TRP A 1 11  ? -23.41195 31.96720 -23.71927 1.000 26.72602 ? 10  TRP A C   1 
ATOM   76   O O   . TRP A 1 11  ? -23.89038 30.98661 -23.13214 1.000 25.03285 ? 10  TRP A O   1 
ATOM   77   C CB  . TRP A 1 11  ? -21.06760 32.77625 -23.29299 1.000 27.67674 ? 10  TRP A CB  1 
ATOM   78   C CG  . TRP A 1 11  ? -20.90448 32.18528 -21.92054 1.000 29.59198 ? 10  TRP A CG  1 
ATOM   79   C CD1 . TRP A 1 11  ? -21.25825 30.92433 -21.51120 1.000 23.94829 ? 10  TRP A CD1 1 
ATOM   80   C CD2 . TRP A 1 11  ? -20.34681 32.83788 -20.77042 1.000 28.28235 ? 10  TRP A CD2 1 
ATOM   81   N NE1 . TRP A 1 11  ? -20.95281 30.76243 -20.18078 1.000 28.64850 ? 10  TRP A NE1 1 
ATOM   82   C CE2 . TRP A 1 11  ? -20.39829 31.92286 -19.70290 1.000 27.51041 ? 10  TRP A CE2 1 
ATOM   83   C CE3 . TRP A 1 11  ? -19.82176 34.11267 -20.53963 1.000 30.86642 ? 10  TRP A CE3 1 
ATOM   84   C CZ2 . TRP A 1 11  ? -19.93077 32.23983 -18.42335 1.000 29.69018 ? 10  TRP A CZ2 1 
ATOM   85   C CZ3 . TRP A 1 11  ? -19.35388 34.42276 -19.26689 1.000 26.74673 ? 10  TRP A CZ3 1 
ATOM   86   C CH2 . TRP A 1 11  ? -19.41562 33.49214 -18.23145 1.000 29.42213 ? 10  TRP A CH2 1 
ATOM   87   N N   . ALA A 1 12  ? -24.12638 33.07492 -23.94122 1.000 25.48526 ? 11  ALA A N   1 
ATOM   88   C CA  . ALA A 1 12  ? -25.49614 33.17131 -23.44078 1.000 26.01665 ? 11  ALA A CA  1 
ATOM   89   C C   . ALA A 1 12  ? -26.39169 32.11884 -24.08364 1.000 26.70729 ? 11  ALA A C   1 
ATOM   90   O O   . ALA A 1 12  ? -27.22689 31.50588 -23.40980 1.000 21.93628 ? 11  ALA A O   1 
ATOM   91   C CB  . ALA A 1 12  ? -26.05501 34.57354 -23.69775 1.000 24.83755 ? 11  ALA A CB  1 
ATOM   92   N N   . LYS A 1 13  ? -26.23816 31.90371 -25.39242 1.000 25.16763 ? 12  LYS A N   1 
ATOM   93   C CA  . LYS A 1 13  ? -27.05631 30.90708 -26.07307 1.000 26.13722 ? 12  LYS A CA  1 
ATOM   94   C C   . LYS A 1 13  ? -26.82758 29.51631 -25.48717 1.000 27.75578 ? 12  LYS A C   1 
ATOM   95   O O   . LYS A 1 13  ? -27.77433 28.74441 -25.31662 1.000 27.44594 ? 12  LYS A O   1 
ATOM   96   C CB  . LYS A 1 13  ? -26.75618 30.91535 -27.57162 1.000 26.80474 ? 12  LYS A CB  1 
ATOM   97   C CG  . LYS A 1 13  ? -27.72569 31.75095 -28.41217 1.000 34.42944 ? 12  LYS A CG  1 
ATOM   98   C CD  . LYS A 1 13  ? -27.10589 32.15940 -29.74075 1.000 35.04831 ? 12  LYS A CD  1 
ATOM   99   C CE  . LYS A 1 13  ? -27.79560 33.37304 -30.33330 1.000 38.53091 ? 12  LYS A CE  1 
ATOM   100  N NZ  . LYS A 1 13  ? -29.04318 33.05591 -31.04796 1.000 43.11401 ? 12  LYS A NZ  1 
ATOM   101  N N   . SER A 1 14  ? -25.57528 29.18608 -25.16162 1.000 25.89403 ? 13  SER A N   1 
ATOM   102  C CA  . SER A 1 14  ? -25.27633 27.88180 -24.58195 1.000 27.47293 ? 13  SER A CA  1 
ATOM   103  C C   . SER A 1 14  ? -25.82168 27.76569 -23.15466 1.000 26.67335 ? 13  SER A C   1 
ATOM   104  O O   . SER A 1 14  ? -26.32067 26.70530 -22.76288 1.000 24.38003 ? 13  SER A O   1 
ATOM   105  C CB  . SER A 1 14  ? -23.76387 27.63767 -24.64118 1.000 27.01120 ? 13  SER A CB  1 
ATOM   106  O OG  . SER A 1 14  ? -23.30895 26.86008 -23.54986 1.000 35.99318 ? 13  SER A OG  1 
ATOM   107  N N   . ILE A 1 15  ? -25.75460 28.84614 -22.36897 1.000 23.62397 ? 14  ILE A N   1 
ATOM   108  C CA  . ILE A 1 15  ? -26.38598 28.85124 -21.04827 1.000 27.44831 ? 14  ILE A CA  1 
ATOM   109  C C   . ILE A 1 15  ? -27.87945 28.54350 -21.16899 1.000 26.13300 ? 14  ILE A C   1 
ATOM   110  O O   . ILE A 1 15  ? -28.42064 27.69709 -20.44638 1.000 25.99853 ? 14  ILE A O   1 
ATOM   111  C CB  . ILE A 1 15  ? -26.14211 30.19989 -20.33834 1.000 24.72713 ? 14  ILE A CB  1 
ATOM   112  C CG1 . ILE A 1 15  ? -24.66797 30.34626 -19.94490 1.000 27.59707 ? 14  ILE A CG1 1 
ATOM   113  C CG2 . ILE A 1 15  ? -27.04245 30.34716 -19.09637 1.000 19.52470 ? 14  ILE A CG2 1 
ATOM   114  C CD1 . ILE A 1 15  ? -24.21752 31.80375 -19.80674 1.000 25.66005 ? 14  ILE A CD1 1 
ATOM   115  N N   . ILE A 1 16  ? -28.56619 29.22116 -22.09120 1.000 24.00121 ? 15  ILE A N   1 
ATOM   116  C CA  . ILE A 1 16  ? -30.00717 29.01511 -22.23260 1.000 28.59244 ? 15  ILE A CA  1 
ATOM   117  C C   . ILE A 1 16  ? -30.31487 27.57596 -22.64578 1.000 27.01881 ? 15  ILE A C   1 
ATOM   118  O O   . ILE A 1 16  ? -31.20698 26.93207 -22.07584 1.000 23.48172 ? 15  ILE A O   1 
ATOM   119  C CB  . ILE A 1 16  ? -30.60597 30.04563 -23.21126 1.000 24.99609 ? 15  ILE A CB  1 
ATOM   120  C CG1 . ILE A 1 16  ? -30.49831 31.44810 -22.60306 1.000 23.30165 ? 15  ILE A CG1 1 
ATOM   121  C CG2 . ILE A 1 16  ? -32.05582 29.69884 -23.57380 1.000 22.46882 ? 15  ILE A CG2 1 
ATOM   122  C CD1 . ILE A 1 16  ? -31.29651 31.61283 -21.31539 1.000 23.23060 ? 15  ILE A CD1 1 
ATOM   123  N N   . GLU A 1 17  ? -29.56530 27.03490 -23.61201 1.000 24.51657 ? 16  GLU A N   1 
ATOM   124  C CA  . GLU A 1 17  ? -29.80075 25.65078 -24.02547 1.000 23.77909 ? 16  GLU A CA  1 
ATOM   125  C C   . GLU A 1 17  ? -29.58496 24.68442 -22.86702 1.000 26.43848 ? 16  GLU A C   1 
ATOM   126  O O   . GLU A 1 17  ? -30.33566 23.71376 -22.70418 1.000 25.97136 ? 16  GLU A O   1 
ATOM   127  C CB  . GLU A 1 17  ? -28.90049 25.28734 -25.21425 1.000 23.87101 ? 16  GLU A CB  1 
ATOM   128  C CG  . GLU A 1 17  ? -29.36378 25.90567 -26.53512 1.000 28.00665 ? 16  GLU A CG  1 
ATOM   129  C CD  . GLU A 1 17  ? -30.88040 25.78612 -26.73027 1.000 32.48574 ? 16  GLU A CD  1 
ATOM   130  O OE1 . GLU A 1 17  ? -31.37096 24.64872 -26.85883 1.000 31.59338 ? 16  GLU A OE1 1 
ATOM   131  O OE2 . GLU A 1 17  ? -31.58900 26.81884 -26.74380 1.000 31.17886 ? 16  GLU A OE2 1 
ATOM   132  N N   . LYS A 1 18  ? -28.57876 24.94356 -22.03486 1.000 23.97109 ? 17  LYS A N   1 
ATOM   133  C CA  . LYS A 1 18  ? -28.36540 24.09937 -20.86436 1.000 27.45995 ? 17  LYS A CA  1 
ATOM   134  C C   . LYS A 1 18  ? -29.55313 24.17079 -19.90801 1.000 26.81661 ? 17  LYS A C   1 
ATOM   135  O O   . LYS A 1 18  ? -30.01325 23.14299 -19.39184 1.000 25.51637 ? 17  LYS A O   1 
ATOM   136  C CB  . LYS A 1 18  ? -27.07109 24.51713 -20.16513 1.000 26.87631 ? 17  LYS A CB  1 
ATOM   137  C CG  . LYS A 1 18  ? -26.93035 24.03427 -18.74564 1.000 29.20014 ? 17  LYS A CG  1 
ATOM   138  C CD  . LYS A 1 18  ? -25.53140 24.37486 -18.22407 1.000 37.04687 ? 17  LYS A CD  1 
ATOM   139  C CE  . LYS A 1 18  ? -25.56261 24.89744 -16.80578 1.000 40.58387 ? 17  LYS A CE  1 
ATOM   140  N NZ  . LYS A 1 18  ? -24.52640 24.22753 -15.95061 1.000 46.73559 ? 17  LYS A NZ  1 
ATOM   141  N N   . GLU A 1 19  ? -30.05504 25.37811 -19.65156 1.000 21.91293 ? 18  GLU A N   1 
ATOM   142  C CA  . GLU A 1 19  ? -31.18185 25.53227 -18.73849 1.000 26.47719 ? 18  GLU A CA  1 
ATOM   143  C C   . GLU A 1 19  ? -32.44198 24.88158 -19.30631 1.000 26.32079 ? 18  GLU A C   1 
ATOM   144  O O   . GLU A 1 19  ? -33.14854 24.15738 -18.59505 1.000 24.74053 ? 18  GLU A O   1 
ATOM   145  C CB  . GLU A 1 19  ? -31.41985 27.01064 -18.45582 1.000 22.55983 ? 18  GLU A CB  1 
ATOM   146  C CG  . GLU A 1 19  ? -30.35842 27.66440 -17.58044 1.000 23.96158 ? 18  GLU A CG  1 
ATOM   147  C CD  . GLU A 1 19  ? -29.98658 26.82194 -16.36890 1.000 28.04264 ? 18  GLU A CD  1 
ATOM   148  O OE1 . GLU A 1 19  ? -30.91043 26.34530 -15.66867 1.000 27.95837 ? 18  GLU A OE1 1 
ATOM   149  O OE2 . GLU A 1 19  ? -28.77258 26.66525 -16.09623 1.000 26.39748 ? 18  GLU A OE2 1 
ATOM   150  N N   . VAL A 1 20  ? -32.72972 25.11660 -20.59244 1.000 25.37459 ? 19  VAL A N   1 
ATOM   151  C CA  . VAL A 1 20  ? -33.88395 24.48041 -21.21950 1.000 25.61548 ? 19  VAL A CA  1 
ATOM   152  C C   . VAL A 1 20  ? -33.80581 22.96735 -21.08331 1.000 25.45018 ? 19  VAL A C   1 
ATOM   153  O O   . VAL A 1 20  ? -34.80199 22.30924 -20.74975 1.000 24.54115 ? 19  VAL A O   1 
ATOM   154  C CB  . VAL A 1 20  ? -34.00259 24.90084 -22.69168 1.000 25.45971 ? 19  VAL A CB  1 
ATOM   155  C CG1 . VAL A 1 20  ? -35.09985 24.08861 -23.37964 1.000 20.72060 ? 19  VAL A CG1 1 
ATOM   156  C CG2 . VAL A 1 20  ? -34.29010 26.39342 -22.78412 1.000 23.22095 ? 19  VAL A CG2 1 
ATOM   157  N N   . GLU A 1 21  ? -32.62175 22.39221 -21.31361 1.000 22.81748 ? 20  GLU A N   1 
ATOM   158  C CA  . GLU A 1 21  ? -32.47423 20.94264 -21.19068 1.000 28.12652 ? 20  GLU A CA  1 
ATOM   159  C C   . GLU A 1 21  ? -32.72563 20.47455 -19.76240 1.000 27.04742 ? 20  GLU A C   1 
ATOM   160  O O   . GLU A 1 21  ? -33.29435 19.39746 -19.54766 1.000 27.57658 ? 20  GLU A O   1 
ATOM   161  C CB  . GLU A 1 21  ? -31.08513 20.50510 -21.64430 1.000 28.48428 ? 20  GLU A CB  1 
ATOM   162  C CG  . GLU A 1 21  ? -30.90649 20.52700 -23.15643 1.000 35.87652 ? 20  GLU A CG  1 
ATOM   163  C CD  . GLU A 1 21  ? -29.49275 20.15041 -23.57796 1.000 49.54800 ? 20  GLU A CD  1 
ATOM   164  O OE1 . GLU A 1 21  ? -28.85954 19.33032 -22.86477 1.000 53.59824 ? 20  GLU A OE1 1 
ATOM   165  O OE2 . GLU A 1 21  ? -29.01701 20.67663 -24.61457 1.000 57.53007 ? 20  GLU A OE2 1 
ATOM   166  N N   . ALA A 1 22  ? -32.30031 21.26156 -18.77095 1.000 23.57869 ? 21  ALA A N   1 
ATOM   167  C CA  . ALA A 1 22  ? -32.56291 20.89117 -17.38422 1.000 25.36185 ? 21  ALA A CA  1 
ATOM   168  C C   . ALA A 1 22  ? -34.05569 20.89377 -17.09266 1.000 26.73628 ? 21  ALA A C   1 
ATOM   169  O O   . ALA A 1 22  ? -34.56411 19.98509 -16.42687 1.000 25.68666 ? 21  ALA A O   1 
ATOM   170  C CB  . ALA A 1 22  ? -31.83502 21.84232 -16.43013 1.000 26.22658 ? 21  ALA A CB  1 
ATOM   171  N N   . TRP A 1 23  ? -34.77157 21.91156 -17.58428 1.000 24.94160 ? 22  TRP A N   1 
ATOM   172  C CA  . TRP A 1 23  ? -36.21211 21.98917 -17.36616 1.000 25.75127 ? 22  TRP A CA  1 
ATOM   173  C C   . TRP A 1 23  ? -36.94246 20.88031 -18.11034 1.000 26.44322 ? 22  TRP A C   1 
ATOM   174  O O   . TRP A 1 23  ? -37.95009 20.35692 -17.61934 1.000 23.32405 ? 22  TRP A O   1 
ATOM   175  C CB  . TRP A 1 23  ? -36.74840 23.35386 -17.81572 1.000 24.43794 ? 22  TRP A CB  1 
ATOM   176  C CG  . TRP A 1 23  ? -36.52588 24.43201 -16.82522 1.000 24.52603 ? 22  TRP A CG  1 
ATOM   177  C CD1 . TRP A 1 23  ? -35.40936 25.20332 -16.69480 1.000 22.50647 ? 22  TRP A CD1 1 
ATOM   178  C CD2 . TRP A 1 23  ? -37.43733 24.86184 -15.80497 1.000 23.39579 ? 22  TRP A CD2 1 
ATOM   179  N NE1 . TRP A 1 23  ? -35.57130 26.09546 -15.66411 1.000 24.73269 ? 22  TRP A NE1 1 
ATOM   180  C CE2 . TRP A 1 23  ? -36.80527 25.90378 -15.09679 1.000 24.15056 ? 22  TRP A CE2 1 
ATOM   181  C CE3 . TRP A 1 23  ? -38.72388 24.46547 -15.42256 1.000 22.25567 ? 22  TRP A CE3 1 
ATOM   182  C CZ2 . TRP A 1 23  ? -37.41444 26.56109 -14.02600 1.000 24.06583 ? 22  TRP A CZ2 1 
ATOM   183  C CZ3 . TRP A 1 23  ? -39.33067 25.11859 -14.36496 1.000 20.23620 ? 22  TRP A CZ3 1 
ATOM   184  C CH2 . TRP A 1 23  ? -38.67498 26.15442 -13.67298 1.000 23.94228 ? 22  TRP A CH2 1 
ATOM   185  N N   . GLU A 1 24  ? -36.46502 20.52680 -19.30949 1.000 23.00074 ? 23  GLU A N   1 
ATOM   186  C CA  . GLU A 1 24  ? -37.13005 19.50732 -20.11053 1.000 25.46723 ? 23  GLU A CA  1 
ATOM   187  C C   . GLU A 1 24  ? -36.82107 18.09612 -19.62903 1.000 27.21827 ? 23  GLU A C   1 
ATOM   188  O O   . GLU A 1 24  ? -37.50217 17.15306 -20.04379 1.000 27.67748 ? 23  GLU A O   1 
ATOM   189  C CB  . GLU A 1 24  ? -36.75356 19.65780 -21.58985 1.000 25.14109 ? 23  GLU A CB  1 
ATOM   190  C CG  . GLU A 1 24  ? -37.50426 20.79255 -22.27598 1.000 26.10238 ? 23  GLU A CG  1 
ATOM   191  C CD  . GLU A 1 24  ? -37.10118 21.00326 -23.73355 1.000 29.27410 ? 23  GLU A CD  1 
ATOM   192  O OE1 . GLU A 1 24  ? -36.09738 20.41657 -24.18021 1.000 28.23758 ? 23  GLU A OE1 1 
ATOM   193  O OE2 . GLU A 1 24  ? -37.79518 21.76698 -24.43599 1.000 29.79823 ? 23  GLU A OE2 1 
ATOM   194  N N   . ALA A 1 25  ? -35.82573 17.93200 -18.75955 1.000 24.57710 ? 24  ALA A N   1 
ATOM   195  C CA  . ALA A 1 25  ? -35.53820 16.63197 -18.17202 1.000 30.50466 ? 24  ALA A CA  1 
ATOM   196  C C   . ALA A 1 25  ? -36.49239 16.28290 -17.04733 1.000 26.84151 ? 24  ALA A C   1 
ATOM   197  O O   . ALA A 1 25  ? -36.46543 15.14466 -16.56725 1.000 29.11644 ? 24  ALA A O   1 
ATOM   198  C CB  . ALA A 1 25  ? -34.10088 16.57748 -17.63677 1.000 24.44252 ? 24  ALA A CB  1 
ATOM   199  N N   . ILE A 1 26  ? -37.31185 17.23543 -16.59880 1.000 27.30605 ? 25  ILE A N   1 
ATOM   200  C CA  . ILE A 1 26  ? -38.25163 16.94034 -15.52223 1.000 27.49211 ? 25  ILE A CA  1 
ATOM   201  C C   . ILE A 1 26  ? -39.25027 15.87862 -15.96786 1.000 26.44738 ? 25  ILE A C   1 
ATOM   202  O O   . ILE A 1 26  ? -39.56804 14.95037 -15.21338 1.000 26.41691 ? 25  ILE A O   1 
ATOM   203  C CB  . ILE A 1 26  ? -38.95612 18.22806 -15.05565 1.000 25.78820 ? 25  ILE A CB  1 
ATOM   204  C CG1 . ILE A 1 26  ? -37.94162 19.22741 -14.50527 1.000 27.37339 ? 25  ILE A CG1 1 
ATOM   205  C CG2 . ILE A 1 26  ? -39.96154 17.92050 -13.96640 1.000 26.96026 ? 25  ILE A CG2 1 
ATOM   206  C CD1 . ILE A 1 26  ? -38.56752 20.58517 -14.21792 1.000 27.66228 ? 25  ILE A CD1 1 
ATOM   207  N N   . GLY A 1 27  ? -39.73857 15.98052 -17.20138 1.000 25.72834 ? 26  GLY A N   1 
ATOM   208  C CA  . GLY A 1 27  ? -40.71606 15.04255 -17.72189 1.000 26.93677 ? 26  GLY A CA  1 
ATOM   209  C C   . GLY A 1 27  ? -42.16795 15.48473 -17.68270 1.000 29.40017 ? 26  GLY A C   1 
ATOM   210  O O   . GLY A 1 27  ? -43.05044 14.64374 -17.89074 1.000 26.65329 ? 26  GLY A O   1 
ATOM   211  N N   . VAL A 1 28  ? -42.44747 16.76044 -17.40304 1.000 27.00535 ? 27  VAL A N   1 
ATOM   212  C CA  . VAL A 1 28  ? -43.78388 17.33401 -17.53713 1.000 22.13987 ? 27  VAL A CA  1 
ATOM   213  C C   . VAL A 1 28  ? -43.67771 18.52839 -18.47719 1.000 24.78420 ? 27  VAL A C   1 
ATOM   214  O O   . VAL A 1 28  ? -42.58304 19.01235 -18.77513 1.000 24.70801 ? 27  VAL A O   1 
ATOM   215  C CB  . VAL A 1 28  ? -44.39084 17.75898 -16.18553 1.000 21.92934 ? 27  VAL A CB  1 
ATOM   216  C CG1 . VAL A 1 28  ? -44.40337 16.60012 -15.21596 1.000 20.27950 ? 27  VAL A CG1 1 
ATOM   217  C CG2 . VAL A 1 28  ? -43.63316 18.95858 -15.60097 1.000 20.82073 ? 27  VAL A CG2 1 
ATOM   218  N N   . ASP A 1 29  ? -44.83215 19.00970 -18.93972 1.000 21.26434 ? 28  ASP A N   1 
ATOM   219  C CA  . ASP A 1 29  ? -44.84607 20.07964 -19.93318 1.000 23.44879 ? 28  ASP A CA  1 
ATOM   220  C C   . ASP A 1 29  ? -44.21061 21.34620 -19.36761 1.000 24.96797 ? 28  ASP A C   1 
ATOM   221  O O   . ASP A 1 29  ? -44.71926 21.91945 -18.39814 1.000 23.10769 ? 28  ASP A O   1 
ATOM   222  C CB  . ASP A 1 29  ? -46.28258 20.34126 -20.40265 1.000 23.51745 ? 28  ASP A CB  1 
ATOM   223  C CG  . ASP A 1 29  ? -46.39116 21.50602 -21.39698 1.000 29.84322 ? 28  ASP A CG  1 
ATOM   224  O OD1 . ASP A 1 29  ? -45.36484 21.93587 -21.95446 1.000 31.40650 ? 28  ASP A OD1 1 
ATOM   225  O OD2 . ASP A 1 29  ? -47.52362 21.98217 -21.64501 1.000 33.54129 ? 28  ASP A OD2 1 
ATOM   226  N N   . VAL A 1 30  ? -43.08916 21.77557 -19.94579 1.000 21.39631 ? 29  VAL A N   1 
ATOM   227  C CA  . VAL A 1 30  ? -42.42871 23.01157 -19.54517 1.000 21.72781 ? 29  VAL A CA  1 
ATOM   228  C C   . VAL A 1 30  ? -42.25589 23.94924 -20.73265 1.000 27.07376 ? 29  VAL A C   1 
ATOM   229  O O   . VAL A 1 30  ? -41.41352 24.85877 -20.69744 1.000 22.17870 ? 29  VAL A O   1 
ATOM   230  C CB  . VAL A 1 30  ? -41.06908 22.73815 -18.87446 1.000 22.81835 ? 29  VAL A CB  1 
ATOM   231  C CG1 . VAL A 1 30  ? -41.24158 21.95045 -17.57718 1.000 18.64074 ? 29  VAL A CG1 1 
ATOM   232  C CG2 . VAL A 1 30  ? -40.13956 22.02895 -19.85199 1.000 20.78262 ? 29  VAL A CG2 1 
ATOM   233  N N   . ARG A 1 31  ? -43.03792 23.72305 -21.79436 1.000 23.69281 ? 30  ARG A N   1 
ATOM   234  C CA  . ARG A 1 31  ? -42.88854 24.49794 -23.02151 1.000 25.06972 ? 30  ARG A CA  1 
ATOM   235  C C   . ARG A 1 31  ? -42.92804 26.00412 -22.75915 1.000 23.90350 ? 30  ARG A C   1 
ATOM   236  O O   . ARG A 1 31  ? -42.19581 26.76948 -23.39711 1.000 26.18748 ? 30  ARG A O   1 
ATOM   237  C CB  . ARG A 1 31  ? -43.98245 24.09193 -24.01515 1.000 27.40349 ? 30  ARG A CB  1 
ATOM   238  C CG  . ARG A 1 31  ? -43.66857 22.80993 -24.83335 1.000 31.88167 ? 30  ARG A CG  1 
ATOM   239  C CD  . ARG A 1 31  ? -44.91501 22.31879 -25.56350 1.000 29.94053 ? 30  ARG A CD  1 
ATOM   240  N NE  . ARG A 1 31  ? -46.05833 22.47662 -24.67885 1.000 36.54695 ? 30  ARG A NE  1 
ATOM   241  C CZ  . ARG A 1 31  ? -47.32199 22.54721 -25.06661 1.000 41.54713 ? 30  ARG A CZ  1 
ATOM   242  N NH1 . ARG A 1 31  ? -47.65452 22.53027 -26.34895 1.000 42.46976 ? 30  ARG A NH1 1 
ATOM   243  N NH2 . ARG A 1 31  ? -48.27423 22.65640 -24.14329 1.000 32.80513 ? 30  ARG A NH2 1 
ATOM   244  N N   . GLU A 1 32  ? -43.76746 26.45507 -21.82141 1.000 20.38290 ? 31  GLU A N   1 
ATOM   245  C CA  . GLU A 1 32  ? -43.88170 27.89535 -21.60221 1.000 24.27781 ? 31  GLU A CA  1 
ATOM   246  C C   . GLU A 1 32  ? -42.61113 28.45995 -20.99035 1.000 23.27942 ? 31  GLU A C   1 
ATOM   247  O O   . GLU A 1 32  ? -42.19179 29.57295 -21.32975 1.000 22.44979 ? 31  GLU A O   1 
ATOM   248  C CB  . GLU A 1 32  ? -45.08300 28.21805 -20.71328 1.000 22.88357 ? 31  GLU A CB  1 
ATOM   249  C CG  . GLU A 1 32  ? -45.34423 29.71166 -20.58114 1.000 25.08123 ? 31  GLU A CG  1 
ATOM   250  C CD  . GLU A 1 32  ? -46.56522 30.04347 -19.72083 1.000 27.56569 ? 31  GLU A CD  1 
ATOM   251  O OE1 . GLU A 1 32  ? -47.42802 29.16479 -19.50760 1.000 24.04266 ? 31  GLU A OE1 1 
ATOM   252  O OE2 . GLU A 1 32  ? -46.64975 31.19478 -19.25078 1.000 27.50571 ? 31  GLU A OE2 1 
ATOM   253  N N   . VAL A 1 33  ? -41.99281 27.71126 -20.07874 1.000 18.77701 ? 32  VAL A N   1 
ATOM   254  C CA  . VAL A 1 33  ? -40.74331 28.16223 -19.47920 1.000 22.72218 ? 32  VAL A CA  1 
ATOM   255  C C   . VAL A 1 33  ? -39.61260 28.12211 -20.50439 1.000 24.10104 ? 32  VAL A C   1 
ATOM   256  O O   . VAL A 1 33  ? -38.78009 29.03843 -20.56851 1.000 21.75600 ? 32  VAL A O   1 
ATOM   257  C CB  . VAL A 1 33  ? -40.41298 27.31422 -18.24007 1.000 23.90731 ? 32  VAL A CB  1 
ATOM   258  C CG1 . VAL A 1 33  ? -38.99223 27.63671 -17.72700 1.000 21.28803 ? 32  VAL A CG1 1 
ATOM   259  C CG2 . VAL A 1 33  ? -41.47430 27.51842 -17.15164 1.000 20.71446 ? 32  VAL A CG2 1 
ATOM   260  N N   . ALA A 1 34  ? -39.56011 27.06176 -21.31611 1.000 23.15781 ? 33  ALA A N   1 
ATOM   261  C CA  . ALA A 1 34  ? -38.55440 26.97598 -22.36971 1.000 20.27611 ? 33  ALA A CA  1 
ATOM   262  C C   . ALA A 1 34  ? -38.67829 28.14550 -23.33471 1.000 22.48177 ? 33  ALA A C   1 
ATOM   263  O O   . ALA A 1 34  ? -37.67687 28.75601 -23.72157 1.000 23.57236 ? 33  ALA A O   1 
ATOM   264  C CB  . ALA A 1 34  ? -38.68731 25.64412 -23.11870 1.000 23.15904 ? 33  ALA A CB  1 
ATOM   265  N N   . ALA A 1 35  ? -39.90528 28.46459 -23.74437 1.000 21.46274 ? 34  ALA A N   1 
ATOM   266  C CA  . ALA A 1 35  ? -40.10407 29.59004 -24.64812 1.000 24.65909 ? 34  ALA A CA  1 
ATOM   267  C C   . ALA A 1 35  ? -39.63851 30.89452 -24.01031 1.000 26.19819 ? 34  ALA A C   1 
ATOM   268  O O   . ALA A 1 35  ? -38.99343 31.72250 -24.67119 1.000 23.93304 ? 34  ALA A O   1 
ATOM   269  C CB  . ALA A 1 35  ? -41.57880 29.67999 -25.05507 1.000 22.67201 ? 34  ALA A CB  1 
ATOM   270  N N   . PHE A 1 36  ? -39.94996 31.09492 -22.72401 1.000 21.98991 ? 35  PHE A N   1 
ATOM   271  C CA  . PHE A 1 36  ? -39.50915 32.31120 -22.03801 1.000 22.89614 ? 35  PHE A CA  1 
ATOM   272  C C   . PHE A 1 36  ? -37.98929 32.40193 -22.00731 1.000 24.67073 ? 35  PHE A C   1 
ATOM   273  O O   . PHE A 1 36  ? -37.41473 33.45593 -22.31363 1.000 24.15875 ? 35  PHE A O   1 
ATOM   274  C CB  . PHE A 1 36  ? -40.06804 32.37104 -20.61038 1.000 22.67960 ? 35  PHE A CB  1 
ATOM   275  C CG  . PHE A 1 36  ? -39.36831 33.38459 -19.73122 1.000 22.10248 ? 35  PHE A CG  1 
ATOM   276  C CD1 . PHE A 1 36  ? -39.51128 34.74905 -19.96428 1.000 23.49383 ? 35  PHE A CD1 1 
ATOM   277  C CD2 . PHE A 1 36  ? -38.55282 32.97152 -18.68412 1.000 21.35276 ? 35  PHE A CD2 1 
ATOM   278  C CE1 . PHE A 1 36  ? -38.85413 35.68758 -19.16131 1.000 22.39857 ? 35  PHE A CE1 1 
ATOM   279  C CE2 . PHE A 1 36  ? -37.89028 33.90079 -17.87198 1.000 20.68701 ? 35  PHE A CE2 1 
ATOM   280  C CZ  . PHE A 1 36  ? -38.04718 35.26046 -18.11062 1.000 23.91524 ? 35  PHE A CZ  1 
ATOM   281  N N   . LEU A 1 37  ? -37.31438 31.30192 -21.64608 1.000 20.36752 ? 36  LEU A N   1 
ATOM   282  C CA  . LEU A 1 37  ? -35.85714 31.33898 -21.60218 1.000 22.92866 ? 36  LEU A CA  1 
ATOM   283  C C   . LEU A 1 37  ? -35.27508 31.67807 -22.96974 1.000 26.55139 ? 36  LEU A C   1 
ATOM   284  O O   . LEU A 1 37  ? -34.36256 32.50808 -23.07693 1.000 21.97667 ? 36  LEU A O   1 
ATOM   285  C CB  . LEU A 1 37  ? -35.29964 30.00913 -21.09035 1.000 20.71107 ? 36  LEU A CB  1 
ATOM   286  C CG  . LEU A 1 37  ? -35.54810 29.75660 -19.58996 1.000 23.80129 ? 36  LEU A CG  1 
ATOM   287  C CD1 . LEU A 1 37  ? -35.17622 28.33755 -19.22846 1.000 21.75465 ? 36  LEU A CD1 1 
ATOM   288  C CD2 . LEU A 1 37  ? -34.80438 30.76954 -18.69389 1.000 20.36029 ? 36  LEU A CD2 1 
ATOM   289  N N   . ARG A 1 38  ? -35.79902 31.05549 -24.02790 1.000 23.21527 ? 37  ARG A N   1 
ATOM   290  C CA  . ARG A 1 38  ? -35.30770 31.31976 -25.37411 1.000 27.79467 ? 37  ARG A CA  1 
ATOM   291  C C   . ARG A 1 38  ? -35.73489 32.67649 -25.90668 1.000 27.38089 ? 37  ARG A C   1 
ATOM   292  O O   . ARG A 1 38  ? -35.24515 33.08361 -26.96415 1.000 27.42715 ? 37  ARG A O   1 
ATOM   293  C CB  . ARG A 1 38  ? -35.78222 30.23174 -26.32838 1.000 23.63347 ? 37  ARG A CB  1 
ATOM   294  C CG  . ARG A 1 38  ? -35.07342 28.93122 -26.07736 1.000 25.88219 ? 37  ARG A CG  1 
ATOM   295  C CD  . ARG A 1 38  ? -35.47870 27.87049 -27.05392 1.000 23.12109 ? 37  ARG A CD  1 
ATOM   296  N NE  . ARG A 1 38  ? -34.59366 26.72149 -26.92976 1.000 23.15977 ? 37  ARG A NE  1 
ATOM   297  C CZ  . ARG A 1 38  ? -35.02151 25.47116 -26.86783 1.000 25.66815 ? 37  ARG A CZ  1 
ATOM   298  N NH1 . ARG A 1 38  ? -36.31405 25.18698 -26.90372 1.000 24.74263 ? 37  ARG A NH1 1 
ATOM   299  N NH2 . ARG A 1 38  ? -34.13385 24.48528 -26.77043 1.000 24.36090 ? 37  ARG A NH2 1 
ATOM   300  N N   . SER A 1 39  ? -36.63753 33.37480 -25.22531 1.000 24.80405 ? 38  SER A N   1 
ATOM   301  C CA  . SER A 1 39  ? -37.00507 34.71373 -25.65479 1.000 26.37161 ? 38  SER A CA  1 
ATOM   302  C C   . SER A 1 39  ? -36.08135 35.78185 -25.09639 1.000 26.37978 ? 38  SER A C   1 
ATOM   303  O O   . SER A 1 39  ? -36.12371 36.91866 -25.58529 1.000 24.62031 ? 38  SER A O   1 
ATOM   304  C CB  . SER A 1 39  ? -38.43239 35.05136 -25.23924 1.000 22.64834 ? 38  SER A CB  1 
ATOM   305  O OG  . SER A 1 39  ? -38.45605 35.36265 -23.86248 1.000 25.27627 ? 38  SER A OG  1 
ATOM   306  N N   . ILE A 1 40  ? -35.26983 35.46439 -24.07877 1.000 21.58858 ? 39  ILE A N   1 
ATOM   307  C CA  . ILE A 1 40  ? -34.41004 36.49270 -23.49407 1.000 24.20615 ? 39  ILE A CA  1 
ATOM   308  C C   . ILE A 1 40  ? -33.40747 36.94246 -24.54848 1.000 25.89828 ? 39  ILE A C   1 
ATOM   309  O O   . ILE A 1 40  ? -32.73957 36.11894 -25.18246 1.000 22.60184 ? 39  ILE A O   1 
ATOM   310  C CB  . ILE A 1 40  ? -33.71852 35.98372 -22.22044 1.000 25.22083 ? 39  ILE A CB  1 
ATOM   311  C CG1 . ILE A 1 40  ? -34.75884 35.54976 -21.17514 1.000 22.05035 ? 39  ILE A CG1 1 
ATOM   312  C CG2 . ILE A 1 40  ? -32.86492 37.08100 -21.62086 1.000 23.03985 ? 39  ILE A CG2 1 
ATOM   313  C CD1 . ILE A 1 40  ? -34.16544 34.71570 -20.03868 1.000 19.30339 ? 39  ILE A CD1 1 
ATOM   314  N N   . SER A 1 41  ? -33.32695 38.25564 -24.76954 1.000 25.02178 ? 40  SER A N   1 
ATOM   315  C CA  . SER A 1 41  ? -32.66965 38.79721 -25.95676 1.000 30.09996 ? 40  SER A CA  1 
ATOM   316  C C   . SER A 1 41  ? -31.40690 39.59295 -25.64461 1.000 28.27211 ? 40  SER A C   1 
ATOM   317  O O   . SER A 1 41  ? -30.86713 40.24944 -26.54306 1.000 27.71205 ? 40  SER A O   1 
ATOM   318  C CB  . SER A 1 41  ? -33.64764 39.68048 -26.73181 1.000 27.78522 ? 40  SER A CB  1 
ATOM   319  O OG  . SER A 1 41  ? -34.10525 40.73131 -25.89284 1.000 26.62729 ? 40  SER A OG  1 
ATOM   320  N N   . ASP A 1 42  ? -30.92634 39.55299 -24.40366 1.000 26.68850 ? 41  ASP A N   1 
ATOM   321  C CA  . ASP A 1 42  ? -29.77228 40.33033 -23.95952 1.000 25.67158 ? 41  ASP A CA  1 
ATOM   322  C C   . ASP A 1 42  ? -28.73150 39.36302 -23.40766 1.000 27.82372 ? 41  ASP A C   1 
ATOM   323  O O   . ASP A 1 42  ? -28.91369 38.80835 -22.31540 1.000 23.68710 ? 41  ASP A O   1 
ATOM   324  C CB  . ASP A 1 42  ? -30.20225 41.35078 -22.90614 1.000 28.15166 ? 41  ASP A CB  1 
ATOM   325  C CG  . ASP A 1 42  ? -29.10325 42.32423 -22.53847 1.000 27.93937 ? 41  ASP A CG  1 
ATOM   326  O OD1 . ASP A 1 42  ? -27.97591 41.88469 -22.24482 1.000 29.53184 ? 41  ASP A OD1 1 
ATOM   327  O OD2 . ASP A 1 42  ? -29.38774 43.53439 -22.49385 1.000 35.74364 ? 41  ASP A OD2 1 
ATOM   328  N N   . ALA A 1 43  ? -27.63514 39.16972 -24.15156 1.000 25.07439 ? 42  ALA A N   1 
ATOM   329  C CA  . ALA A 1 43  ? -26.63587 38.18222 -23.74279 1.000 29.28441 ? 42  ALA A CA  1 
ATOM   330  C C   . ALA A 1 43  ? -26.06633 38.51171 -22.37345 1.000 24.31659 ? 42  ALA A C   1 
ATOM   331  O O   . ALA A 1 43  ? -25.79605 37.61522 -21.57019 1.000 26.12457 ? 42  ALA A O   1 
ATOM   332  C CB  . ALA A 1 43  ? -25.50063 38.09172 -24.77202 1.000 24.12002 ? 42  ALA A CB  1 
ATOM   333  N N   . ARG A 1 44  ? -25.86845 39.79460 -22.09445 1.000 24.81391 ? 43  ARG A N   1 
ATOM   334  C CA  . ARG A 1 44  ? -25.26813 40.18546 -20.82641 1.000 26.62604 ? 43  ARG A CA  1 
ATOM   335  C C   . ARG A 1 44  ? -26.17850 39.84670 -19.65205 1.000 24.97809 ? 43  ARG A C   1 
ATOM   336  O O   . ARG A 1 44  ? -25.70329 39.40682 -18.59993 1.000 26.28285 ? 43  ARG A O   1 
ATOM   337  C CB  . ARG A 1 44  ? -24.94156 41.67495 -20.86784 1.000 32.07937 ? 43  ARG A CB  1 
ATOM   338  C CG  . ARG A 1 44  ? -24.51511 42.24006 -19.56184 1.000 37.97117 ? 43  ARG A CG  1 
ATOM   339  C CD  . ARG A 1 44  ? -23.03512 42.11907 -19.38745 1.000 42.60258 ? 43  ARG A CD  1 
ATOM   340  N NE  . ARG A 1 44  ? -22.65249 42.64283 -18.08560 1.000 47.27166 ? 43  ARG A NE  1 
ATOM   341  C CZ  . ARG A 1 44  ? -22.31572 43.90239 -17.85130 1.000 45.52302 ? 43  ARG A CZ  1 
ATOM   342  N NH1 . ARG A 1 44  ? -22.27097 44.79901 -18.82463 1.000 45.93327 ? 43  ARG A NH1 1 
ATOM   343  N NH2 . ARG A 1 44  ? -21.99781 44.26490 -16.61219 1.000 43.28794 ? 43  ARG A NH2 1 
ATOM   344  N N   . VAL A 1 45  ? -27.49256 40.01210 -19.82201 1.000 24.02435 ? 44  VAL A N   1 
ATOM   345  C CA  . VAL A 1 45  ? -28.42855 39.68788 -18.74501 1.000 23.96968 ? 44  VAL A CA  1 
ATOM   346  C C   . VAL A 1 45  ? -28.44192 38.18838 -18.47480 1.000 26.24869 ? 44  VAL A C   1 
ATOM   347  O O   . VAL A 1 45  ? -28.50994 37.74790 -17.31808 1.000 25.10045 ? 44  VAL A O   1 
ATOM   348  C CB  . VAL A 1 45  ? -29.83094 40.21966 -19.08742 1.000 26.25531 ? 44  VAL A CB  1 
ATOM   349  C CG1 . VAL A 1 45  ? -30.86583 39.71833 -18.08284 1.000 26.25836 ? 44  VAL A CG1 1 
ATOM   350  C CG2 . VAL A 1 45  ? -29.82108 41.75216 -19.11601 1.000 27.37378 ? 44  VAL A CG2 1 
ATOM   351  N N   . ILE A 1 46  ? -28.38261 37.37964 -19.53445 1.000 26.63884 ? 45  ILE A N   1 
ATOM   352  C CA  . ILE A 1 46  ? -28.31990 35.92940 -19.37137 1.000 25.47873 ? 45  ILE A CA  1 
ATOM   353  C C   . ILE A 1 46  ? -27.05643 35.54017 -18.61890 1.000 24.01686 ? 45  ILE A C   1 
ATOM   354  O O   . ILE A 1 46  ? -27.10076 34.79349 -17.63548 1.000 24.64025 ? 45  ILE A O   1 
ATOM   355  C CB  . ILE A 1 46  ? -28.38354 35.23784 -20.74664 1.000 25.30767 ? 45  ILE A CB  1 
ATOM   356  C CG1 . ILE A 1 46  ? -29.77431 35.39685 -21.35556 1.000 22.08338 ? 45  ILE A CG1 1 
ATOM   357  C CG2 . ILE A 1 46  ? -28.00764 33.76286 -20.61171 1.000 23.77122 ? 45  ILE A CG2 1 
ATOM   358  C CD1 . ILE A 1 46  ? -29.85714 35.07348 -22.85297 1.000 25.11943 ? 45  ILE A CD1 1 
ATOM   359  N N   . ILE A 1 47  ? -25.91096 36.06290 -19.06525 1.000 22.43550 ? 46  ILE A N   1 
ATOM   360  C CA  . ILE A 1 47  ? -24.62819 35.72189 -18.45035 1.000 22.08559 ? 46  ILE A CA  1 
ATOM   361  C C   . ILE A 1 47  ? -24.61283 36.10580 -16.97646 1.000 23.28308 ? 46  ILE A C   1 
ATOM   362  O O   . ILE A 1 47  ? -24.18911 35.31989 -16.11982 1.000 22.00126 ? 46  ILE A O   1 
ATOM   363  C CB  . ILE A 1 47  ? -23.47806 36.39447 -19.22147 1.000 22.32890 ? 46  ILE A CB  1 
ATOM   364  C CG1 . ILE A 1 47  ? -23.35018 35.77026 -20.61078 1.000 23.87264 ? 46  ILE A CG1 1 
ATOM   365  C CG2 . ILE A 1 47  ? -22.17113 36.33422 -18.42518 1.000 25.52314 ? 46  ILE A CG2 1 
ATOM   366  C CD1 . ILE A 1 47  ? -22.52554 36.59645 -21.59078 1.000 25.97398 ? 46  ILE A CD1 1 
ATOM   367  N N   . ASP A 1 48  ? -25.05450 37.32845 -16.65973 1.000 21.91145 ? 47  ASP A N   1 
ATOM   368  C CA  . ASP A 1 48  ? -25.00222 37.80456 -15.27926 1.000 21.73129 ? 47  ASP A CA  1 
ATOM   369  C C   . ASP A 1 48  ? -25.92248 36.99626 -14.37236 1.000 26.66033 ? 47  ASP A C   1 
ATOM   370  O O   . ASP A 1 48  ? -25.68495 36.90202 -13.16120 1.000 22.99992 ? 47  ASP A O   1 
ATOM   371  C CB  . ASP A 1 48  ? -25.37672 39.28662 -15.22063 1.000 25.27622 ? 47  ASP A CB  1 
ATOM   372  C CG  . ASP A 1 48  ? -24.27170 40.20566 -15.76153 1.000 34.04772 ? 47  ASP A CG  1 
ATOM   373  O OD1 . ASP A 1 48  ? -23.11728 39.75807 -15.93859 1.000 30.86942 ? 47  ASP A OD1 1 
ATOM   374  O OD2 . ASP A 1 48  ? -24.56278 41.38809 -16.01018 1.000 35.24017 ? 47  ASP A OD2 1 
ATOM   375  N N   . ASN A 1 49  ? -26.95851 36.37873 -14.93368 1.000 24.90610 ? 48  ASN A N   1 
ATOM   376  C CA  . ASN A 1 49  ? -27.90884 35.64120 -14.12199 1.000 24.31354 ? 48  ASN A CA  1 
ATOM   377  C C   . ASN A 1 49  ? -27.76878 34.14042 -14.28143 1.000 25.89428 ? 48  ASN A C   1 
ATOM   378  O O   . ASN A 1 49  ? -28.63501 33.40185 -13.80133 1.000 25.75619 ? 48  ASN A O   1 
ATOM   379  C CB  . ASN A 1 49  ? -29.32788 36.08955 -14.45183 1.000 22.61313 ? 48  ASN A CB  1 
ATOM   380  C CG  . ASN A 1 49  ? -29.60740 37.49213 -13.95519 1.000 21.92344 ? 48  ASN A CG  1 
ATOM   381  O OD1 . ASN A 1 49  ? -29.81164 37.69081 -12.76547 1.000 26.18098 ? 48  ASN A OD1 1 
ATOM   382  N ND2 . ASN A 1 49  ? -29.61188 38.47292 -14.86068 1.000 19.81458 ? 48  ASN A ND2 1 
ATOM   383  N N   . ARG A 1 50  ? -26.68367 33.67128 -14.91482 1.000 24.27213 ? 49  ARG A N   1 
ATOM   384  C CA  . ARG A 1 50  ? -26.56276 32.24976 -15.24491 1.000 25.55804 ? 49  ARG A CA  1 
ATOM   385  C C   . ARG A 1 50  ? -26.57170 31.36639 -14.00238 1.000 25.35259 ? 49  ARG A C   1 
ATOM   386  O O   . ARG A 1 50  ? -27.02049 30.21807 -14.06160 1.000 24.36184 ? 49  ARG A O   1 
ATOM   387  C CB  . ARG A 1 50  ? -25.27990 31.98792 -16.03278 1.000 22.70567 ? 49  ARG A CB  1 
ATOM   388  C CG  . ARG A 1 50  ? -24.00784 32.33035 -15.26157 1.000 24.80218 ? 49  ARG A CG  1 
ATOM   389  C CD  . ARG A 1 50  ? -22.76822 32.26116 -16.15722 1.000 26.13490 ? 49  ARG A CD  1 
ATOM   390  N NE  . ARG A 1 50  ? -21.53698 32.38133 -15.38395 1.000 28.13185 ? 49  ARG A NE  1 
ATOM   391  C CZ  . ARG A 1 50  ? -21.02264 33.53136 -14.96559 1.000 28.61328 ? 49  ARG A CZ  1 
ATOM   392  N NH1 . ARG A 1 50  ? -21.59600 34.68871 -15.24283 1.000 25.20855 ? 49  ARG A NH1 1 
ATOM   393  N NH2 . ARG A 1 50  ? -19.90731 33.51898 -14.24238 1.000 32.92258 ? 49  ARG A NH2 1 
ATOM   394  N N   . ASN A 1 51  ? -26.04652 31.85124 -12.88487 1.000 23.68861 ? 50  ASN A N   1 
ATOM   395  C CA  . ASN A 1 51  ? -26.05314 31.01389 -11.69336 1.000 28.44850 ? 50  ASN A CA  1 
ATOM   396  C C   . ASN A 1 51  ? -27.31889 31.20715 -10.87372 1.000 27.34503 ? 50  ASN A C   1 
ATOM   397  O O   . ASN A 1 51  ? -27.83309 30.24204 -10.29929 1.000 23.02659 ? 50  ASN A O   1 
ATOM   398  C CB  . ASN A 1 51  ? -24.81651 31.29016 -10.83485 1.000 27.21849 ? 50  ASN A CB  1 
ATOM   399  C CG  . ASN A 1 51  ? -23.52944 30.91064 -11.53990 1.000 28.88391 ? 50  ASN A CG  1 
ATOM   400  O OD1 . ASN A 1 51  ? -23.43971 29.85272 -12.14615 1.000 28.48891 ? 50  ASN A OD1 1 
ATOM   401  N ND2 . ASN A 1 51  ? -22.52935 31.76689 -11.45485 1.000 29.05838 ? 50  ASN A ND2 1 
ATOM   402  N N   . LEU A 1 52  ? -27.85657 32.42491 -10.85496 1.000 26.37620 ? 51  LEU A N   1 
ATOM   403  C CA  . LEU A 1 52  ? -29.06976 32.67712 -10.08819 1.000 28.22857 ? 51  LEU A CA  1 
ATOM   404  C C   . LEU A 1 52  ? -30.24620 31.88225 -10.63543 1.000 26.69122 ? 51  LEU A C   1 
ATOM   405  O O   . LEU A 1 52  ? -31.09263 31.42250 -9.86339  1.000 27.37565 ? 51  LEU A O   1 
ATOM   406  C CB  . LEU A 1 52  ? -29.38774 34.17307 -10.08664 1.000 26.19957 ? 51  LEU A CB  1 
ATOM   407  C CG  . LEU A 1 52  ? -28.43971 35.06154 -9.28023  1.000 32.31286 ? 51  LEU A CG  1 
ATOM   408  C CD1 . LEU A 1 52  ? -28.75560 36.53129 -9.49561  1.000 31.64528 ? 51  LEU A CD1 1 
ATOM   409  C CD2 . LEU A 1 52  ? -28.50651 34.71174 -7.79946  1.000 27.49569 ? 51  LEU A CD2 1 
ATOM   410  N N   . ILE A 1 53  ? -30.31055 31.68439 -11.95584 1.000 23.93853 ? 52  ILE A N   1 
ATOM   411  C CA  . ILE A 1 53  ? -31.45551 30.97573 -12.52568 1.000 26.35116 ? 52  ILE A CA  1 
ATOM   412  C C   . ILE A 1 53  ? -31.24128 29.47711 -12.62512 1.000 24.64903 ? 52  ILE A C   1 
ATOM   413  O O   . ILE A 1 53  ? -32.19613 28.74956 -12.95629 1.000 25.61217 ? 52  ILE A O   1 
ATOM   414  C CB  . ILE A 1 53  ? -31.83402 31.48464 -13.93351 1.000 24.34812 ? 52  ILE A CB  1 
ATOM   415  C CG1 . ILE A 1 53  ? -30.70382 31.22607 -14.93369 1.000 25.39990 ? 52  ILE A CG1 1 
ATOM   416  C CG2 . ILE A 1 53  ? -32.18951 32.94351 -13.89270 1.000 24.48010 ? 52  ILE A CG2 1 
ATOM   417  C CD1 . ILE A 1 53  ? -31.13717 31.36536 -16.36136 1.000 27.70240 ? 52  ILE A CD1 1 
ATOM   418  N N   . HIS A 1 54  ? -30.03420 28.99069 -12.34653 1.000 23.84313 ? 53  HIS A N   1 
ATOM   419  C CA  . HIS A 1 54  ? -29.67847 27.63080 -12.72408 1.000 26.70203 ? 53  HIS A CA  1 
ATOM   420  C C   . HIS A 1 54  ? -30.60336 26.61678 -12.05937 1.000 29.26899 ? 53  HIS A C   1 
ATOM   421  O O   . HIS A 1 54  ? -30.88254 26.69638 -10.85655 1.000 26.87764 ? 53  HIS A O   1 
ATOM   422  C CB  . HIS A 1 54  ? -28.22763 27.32849 -12.35620 1.000 26.77899 ? 53  HIS A CB  1 
ATOM   423  C CG  . HIS A 1 54  ? -27.85249 25.89823 -12.57628 1.000 28.16778 ? 53  HIS A CG  1 
ATOM   424  N ND1 . HIS A 1 54  ? -27.92146 25.30031 -13.81594 1.000 30.57460 ? 53  HIS A ND1 1 
ATOM   425  C CD2 . HIS A 1 54  ? -27.43652 24.93866 -11.71597 1.000 28.87305 ? 53  HIS A CD2 1 
ATOM   426  C CE1 . HIS A 1 54  ? -27.54796 24.03425 -13.71364 1.000 31.31521 ? 53  HIS A CE1 1 
ATOM   427  N NE2 . HIS A 1 54  ? -27.25419 23.78941 -12.44792 1.000 32.12468 ? 53  HIS A NE2 1 
ATOM   428  N N   . PHE A 1 55  ? -31.08588 25.66636 -12.85426 1.000 26.44534 ? 54  PHE A N   1 
ATOM   429  C CA  . PHE A 1 55  ? -32.00377 24.63687 -12.38357 1.000 27.96258 ? 54  PHE A CA  1 
ATOM   430  C C   . PHE A 1 55  ? -31.21640 23.35767 -12.11812 1.000 30.75335 ? 54  PHE A C   1 
ATOM   431  O O   . PHE A 1 55  ? -30.62525 22.79461 -13.04879 1.000 31.58929 ? 54  PHE A O   1 
ATOM   432  C CB  . PHE A 1 55  ? -33.09780 24.37704 -13.41855 1.000 24.39551 ? 54  PHE A CB  1 
ATOM   433  C CG  . PHE A 1 55  ? -34.23044 23.52899 -12.90128 1.000 28.50416 ? 54  PHE A CG  1 
ATOM   434  C CD1 . PHE A 1 55  ? -34.15817 22.13820 -12.94110 1.000 27.67281 ? 54  PHE A CD1 1 
ATOM   435  C CD2 . PHE A 1 55  ? -35.36903 24.12196 -12.36816 1.000 25.24706 ? 54  PHE A CD2 1 
ATOM   436  C CE1 . PHE A 1 55  ? -35.20749 21.35747 -12.45907 1.000 25.86868 ? 54  PHE A CE1 1 
ATOM   437  C CE2 . PHE A 1 55  ? -36.40889 23.35273 -11.88710 1.000 26.41277 ? 54  PHE A CE2 1 
ATOM   438  C CZ  . PHE A 1 55  ? -36.32999 21.96347 -11.92627 1.000 25.83391 ? 54  PHE A CZ  1 
ATOM   439  N N   . GLN A 1 56  ? -31.22246 22.89530 -10.86286 1.000 28.95441 ? 55  GLN A N   1 
ATOM   440  C CA  . GLN A 1 56  ? -30.44319 21.72607 -10.46186 1.000 29.90251 ? 55  GLN A CA  1 
ATOM   441  C C   . GLN A 1 56  ? -31.27432 20.46362 -10.62650 1.000 31.95228 ? 55  GLN A C   1 
ATOM   442  O O   . GLN A 1 56  ? -32.34534 20.32731 -10.02375 1.000 32.24437 ? 55  GLN A O   1 
ATOM   443  C CB  . GLN A 1 56  ? -29.94905 21.85468 -9.02305  1.000 33.62356 ? 55  GLN A CB  1 
ATOM   444  C CG  . GLN A 1 56  ? -29.12453 23.10372 -8.81539  1.000 37.89982 ? 55  GLN A CG  1 
ATOM   445  C CD  . GLN A 1 56  ? -28.37432 23.10322 -7.50225  1.000 45.71533 ? 55  GLN A CD  1 
ATOM   446  O OE1 . GLN A 1 56  ? -28.89371 22.68523 -6.46704  1.000 49.09314 ? 55  GLN A OE1 1 
ATOM   447  N NE2 . GLN A 1 56  ? -27.12938 23.56737 -7.54330  1.000 52.49795 ? 55  GLN A NE2 1 
ATOM   448  N N   . SER A 1 57  ? -30.74574 19.52529 -11.40911 1.000 35.09142 ? 56  SER A N   1 
ATOM   449  C CA  . SER A 1 57  ? -31.36831 18.22457 -11.64258 1.000 37.33937 ? 56  SER A CA  1 
ATOM   450  C C   . SER A 1 57  ? -31.37833 17.32668 -10.41020 1.000 35.05166 ? 56  SER A C   1 
ATOM   451  O O   . SER A 1 57  ? -32.12282 16.34603 -10.39261 1.000 38.08054 ? 56  SER A O   1 
ATOM   452  C CB  . SER A 1 57  ? -30.61668 17.49592 -12.75250 1.000 41.20182 ? 56  SER A CB  1 
ATOM   453  O OG  . SER A 1 57  ? -29.32203 17.15114 -12.27127 1.000 44.47829 ? 56  SER A OG  1 
ATOM   454  N N   . SER A 1 58  ? -30.55818 17.61143 -9.39714  1.000 34.51120 ? 57  SER A N   1 
ATOM   455  C CA  . SER A 1 58  ? -30.39679 16.67613 -8.28394  1.000 40.79829 ? 57  SER A CA  1 
ATOM   456  C C   . SER A 1 58  ? -31.60821 16.69789 -7.35539  1.000 42.00969 ? 57  SER A C   1 
ATOM   457  O O   . SER A 1 58  ? -31.92240 15.69001 -6.72236  1.000 49.35473 ? 57  SER A O   1 
ATOM   458  C CB  . SER A 1 58  ? -29.10692 16.98646 -7.50424  1.000 35.62278 ? 57  SER A CB  1 
ATOM   459  O OG  . SER A 1 58  ? -29.16900 18.27992 -6.92492  1.000 48.31073 ? 57  SER A OG  1 
ATOM   460  N N   . GLY A 1 59  ? -32.27965 17.82988 -7.22380  1.000 34.14729 ? 58  GLY A N   1 
ATOM   461  C CA  . GLY A 1 59  ? -33.48362 17.87096 -6.41496  1.000 34.22347 ? 58  GLY A CA  1 
ATOM   462  C C   . GLY A 1 59  ? -34.55612 18.66695 -7.12535  1.000 32.61135 ? 58  GLY A C   1 
ATOM   463  O O   . GLY A 1 59  ? -34.65231 19.89064 -6.93974  1.000 28.26050 ? 58  GLY A O   1 
ATOM   464  N N   . ILE A 1 60  ? -35.36948 17.97723 -7.93480  1.000 28.95922 ? 59  ILE A N   1 
ATOM   465  C CA  . ILE A 1 60  ? -36.26092 18.67073 -8.86404  1.000 25.66324 ? 59  ILE A CA  1 
ATOM   466  C C   . ILE A 1 60  ? -37.32556 19.44182 -8.10953  1.000 25.61222 ? 59  ILE A C   1 
ATOM   467  O O   . ILE A 1 60  ? -37.56086 20.63076 -8.37554  1.000 25.12733 ? 59  ILE A O   1 
ATOM   468  C CB  . ILE A 1 60  ? -36.86958 17.68370 -9.87788  1.000 25.79698 ? 59  ILE A CB  1 
ATOM   469  C CG1 . ILE A 1 60  ? -35.75044 17.12779 -10.77246 1.000 27.41043 ? 59  ILE A CG1 1 
ATOM   470  C CG2 . ILE A 1 60  ? -37.93710 18.37109 -10.71496 1.000 22.48937 ? 59  ILE A CG2 1 
ATOM   471  C CD1 . ILE A 1 60  ? -36.18055 16.00297 -11.67789 1.000 28.81242 ? 59  ILE A CD1 1 
ATOM   472  N N   . SER A 1 61  ? -37.97296 18.79180 -7.13343  1.000 24.08729 ? 60  SER A N   1 
ATOM   473  C CA  . SER A 1 61  ? -39.03582 19.46091 -6.39819  1.000 25.18612 ? 60  SER A CA  1 
ATOM   474  C C   . SER A 1 61  ? -38.53510 20.75144 -5.75970  1.000 27.67948 ? 60  SER A C   1 
ATOM   475  O O   . SER A 1 61  ? -39.18521 21.79992 -5.87413  1.000 23.74174 ? 60  SER A O   1 
ATOM   476  C CB  . SER A 1 61  ? -39.62153 18.53284 -5.33938  1.000 24.35804 ? 60  SER A CB  1 
ATOM   477  O OG  . SER A 1 61  ? -40.37531 17.50429 -5.96397  1.000 26.05167 ? 60  SER A OG  1 
ATOM   478  N N   . TYR A 1 62  ? -37.37586 20.69577 -5.08959  1.000 23.17614 ? 61  TYR A N   1 
ATOM   479  C CA  . TYR A 1 62  ? -36.89585 21.89969 -4.42116  1.000 26.87885 ? 61  TYR A CA  1 
ATOM   480  C C   . TYR A 1 62  ? -36.43021 22.93065 -5.43950  1.000 24.60998 ? 61  TYR A C   1 
ATOM   481  O O   . TYR A 1 62  ? -36.66477 24.12980 -5.25368  1.000 25.08474 ? 61  TYR A O   1 
ATOM   482  C CB  . TYR A 1 62  ? -35.78246 21.58079 -3.41409  1.000 26.68204 ? 61  TYR A CB  1 
ATOM   483  C CG  . TYR A 1 62  ? -35.41523 22.82788 -2.63870  1.000 27.20995 ? 61  TYR A CG  1 
ATOM   484  C CD1 . TYR A 1 62  ? -36.36616 23.48051 -1.87046  1.000 28.09469 ? 61  TYR A CD1 1 
ATOM   485  C CD2 . TYR A 1 62  ? -34.15007 23.39658 -2.73650  1.000 28.65077 ? 61  TYR A CD2 1 
ATOM   486  C CE1 . TYR A 1 62  ? -36.06928 24.63780 -1.18354  1.000 30.09506 ? 61  TYR A CE1 1 
ATOM   487  C CE2 . TYR A 1 62  ? -33.83301 24.56925 -2.05143  1.000 26.93815 ? 61  TYR A CE2 1 
ATOM   488  C CZ  . TYR A 1 62  ? -34.80484 25.18603 -1.27571  1.000 32.29117 ? 61  TYR A CZ  1 
ATOM   489  O OH  . TYR A 1 62  ? -34.55253 26.35800 -0.58475  1.000 30.62107 ? 61  TYR A OH  1 
ATOM   490  N N   . SER A 1 63  ? -35.78856 22.48949 -6.52888  1.000 25.55413 ? 62  SER A N   1 
ATOM   491  C CA  . SER A 1 63  ? -35.43516 23.41109 -7.61093  1.000 25.17789 ? 62  SER A CA  1 
ATOM   492  C C   . SER A 1 63  ? -36.65935 24.15846 -8.12360  1.000 25.44891 ? 62  SER A C   1 
ATOM   493  O O   . SER A 1 63  ? -36.59772 25.36638 -8.37523  1.000 24.25660 ? 62  SER A O   1 
ATOM   494  C CB  . SER A 1 63  ? -34.78505 22.65111 -8.76723  1.000 24.62764 ? 62  SER A CB  1 
ATOM   495  O OG  . SER A 1 63  ? -33.55676 22.07507 -8.39446  1.000 27.17554 ? 62  SER A OG  1 
ATOM   496  N N   . LEU A 1 64  ? -37.77853 23.44969 -8.30931  1.000 23.17870 ? 63  LEU A N   1 
ATOM   497  C CA  . LEU A 1 64  ? -39.00668 24.10227 -8.76079  1.000 23.90450 ? 63  LEU A CA  1 
ATOM   498  C C   . LEU A 1 64  ? -39.50648 25.09412 -7.72485  1.000 23.92939 ? 63  LEU A C   1 
ATOM   499  O O   . LEU A 1 64  ? -39.85451 26.23670 -8.04843  1.000 22.66580 ? 63  LEU A O   1 
ATOM   500  C CB  . LEU A 1 64  ? -40.08210 23.05538 -9.05551  1.000 20.94525 ? 63  LEU A CB  1 
ATOM   501  C CG  . LEU A 1 64  ? -39.90907 22.30394 -10.37182 1.000 21.59205 ? 63  LEU A CG  1 
ATOM   502  C CD1 . LEU A 1 64  ? -40.96256 21.19033 -10.49657 1.000 23.22354 ? 63  LEU A CD1 1 
ATOM   503  C CD2 . LEU A 1 64  ? -40.00556 23.29337 -11.53567 1.000 18.89915 ? 63  LEU A CD2 1 
ATOM   504  N N   . GLU A 1 65  ? -39.53534 24.66994 -6.46544  1.000 23.75194 ? 64  GLU A N   1 
ATOM   505  C CA  . GLU A 1 65  ? -40.16643 25.45179 -5.41316  1.000 24.88570 ? 64  GLU A CA  1 
ATOM   506  C C   . GLU A 1 65  ? -39.34135 26.67609 -5.05677  1.000 23.60321 ? 64  GLU A C   1 
ATOM   507  O O   . GLU A 1 65  ? -39.90045 27.70475 -4.66693  1.000 25.65796 ? 64  GLU A O   1 
ATOM   508  C CB  . GLU A 1 65  ? -40.36672 24.57745 -4.17466  1.000 24.02431 ? 64  GLU A CB  1 
ATOM   509  C CG  . GLU A 1 65  ? -41.31545 25.15948 -3.14507  1.000 25.37645 ? 64  GLU A CG  1 
ATOM   510  C CD  . GLU A 1 65  ? -41.70028 24.14667 -2.08752  1.000 25.36025 ? 64  GLU A CD  1 
ATOM   511  O OE1 . GLU A 1 65  ? -42.65494 23.37525 -2.31731  1.000 24.26663 ? 64  GLU A OE1 1 
ATOM   512  O OE2 . GLU A 1 65  ? -41.04933 24.12975 -1.02102  1.000 27.46709 ? 64  GLU A OE2 1 
ATOM   513  N N   . SER A 1 66  ? -38.02412 26.58119 -5.18078  1.000 22.13253 ? 65  SER A N   1 
ATOM   514  C CA  . SER A 1 66  ? -37.12232 27.66112 -4.82227  1.000 25.93560 ? 65  SER A CA  1 
ATOM   515  C C   . SER A 1 66  ? -36.67630 28.49012 -6.01384  1.000 25.11444 ? 65  SER A C   1 
ATOM   516  O O   . SER A 1 66  ? -35.94737 29.46521 -5.82028  1.000 25.02266 ? 65  SER A O   1 
ATOM   517  C CB  . SER A 1 66  ? -35.88970 27.09759 -4.11839  1.000 25.61483 ? 65  SER A CB  1 
ATOM   518  O OG  . SER A 1 66  ? -35.06339 26.45235 -5.06516  1.000 28.37377 ? 65  SER A OG  1 
ATOM   519  N N   . SER A 1 67  ? -37.07967 28.12508 -7.23109  1.000 24.31889 ? 66  SER A N   1 
ATOM   520  C CA  . SER A 1 67  ? -36.58645 28.82140 -8.41069  1.000 21.19620 ? 66  SER A CA  1 
ATOM   521  C C   . SER A 1 67  ? -36.90967 30.30916 -8.31385  1.000 23.28058 ? 66  SER A C   1 
ATOM   522  O O   . SER A 1 67  ? -38.03051 30.68217 -7.93735  1.000 20.77730 ? 66  SER A O   1 
ATOM   523  C CB  . SER A 1 67  ? -37.20598 28.24864 -9.68793  1.000 22.22563 ? 66  SER A CB  1 
ATOM   524  O OG  . SER A 1 67  ? -36.77780 28.98453 -10.83785 1.000 24.10327 ? 66  SER A OG  1 
ATOM   525  N N   . PRO A 1 68  ? -35.96143 31.18940 -8.64805  1.000 24.94946 ? 67  PRO A N   1 
ATOM   526  C CA  . PRO A 1 68  ? -36.28741 32.62237 -8.69363  1.000 22.38655 ? 67  PRO A CA  1 
ATOM   527  C C   . PRO A 1 68  ? -37.27766 32.96145 -9.78522  1.000 24.15454 ? 67  PRO A C   1 
ATOM   528  O O   . PRO A 1 68  ? -37.79128 34.08955 -9.78759  1.000 25.43489 ? 67  PRO A O   1 
ATOM   529  C CB  . PRO A 1 68  ? -34.93077 33.30929 -8.93355  1.000 23.99417 ? 67  PRO A CB  1 
ATOM   530  C CG  . PRO A 1 68  ? -33.98653 32.22474 -9.34943  1.000 28.30355 ? 67  PRO A CG  1 
ATOM   531  C CD  . PRO A 1 68  ? -34.54164 30.90119 -8.92342  1.000 25.80226 ? 67  PRO A CD  1 
ATOM   532  N N   . LEU A 1 69  ? -37.57412 32.03276 -10.70762 1.000 20.98605 ? 68  LEU A N   1 
ATOM   533  C CA  . LEU A 1 69  ? -38.65027 32.28457 -11.66227 1.000 23.62382 ? 68  LEU A CA  1 
ATOM   534  C C   . LEU A 1 69  ? -40.01748 32.31889 -10.98464 1.000 24.43849 ? 68  LEU A C   1 
ATOM   535  O O   . LEU A 1 69  ? -40.99362 32.71414 -11.62904 1.000 24.86344 ? 68  LEU A O   1 
ATOM   536  C CB  . LEU A 1 69  ? -38.64054 31.23872 -12.79496 1.000 25.02459 ? 68  LEU A CB  1 
ATOM   537  C CG  . LEU A 1 69  ? -37.75703 31.54296 -14.01874 1.000 25.08546 ? 68  LEU A CG  1 
ATOM   538  C CD1 . LEU A 1 69  ? -36.29595 31.74656 -13.63496 1.000 21.06855 ? 68  LEU A CD1 1 
ATOM   539  C CD2 . LEU A 1 69  ? -37.88356 30.48140 -15.12415 1.000 25.86070 ? 68  LEU A CD2 1 
ATOM   540  N N   . ASN A 1 70  ? -40.10847 31.92334 -9.70738  1.000 19.81490 ? 69  ASN A N   1 
ATOM   541  C CA  . ASN A 1 70  ? -41.34545 32.08610 -8.94536  1.000 25.72445 ? 69  ASN A CA  1 
ATOM   542  C C   . ASN A 1 70  ? -41.60579 33.53638 -8.56722  1.000 27.61493 ? 69  ASN A C   1 
ATOM   543  O O   . ASN A 1 70  ? -42.73316 33.87066 -8.18188  1.000 25.37697 ? 69  ASN A O   1 
ATOM   544  C CB  . ASN A 1 70  ? -41.29673 31.26385 -7.65232  1.000 20.88852 ? 69  ASN A CB  1 
ATOM   545  C CG  . ASN A 1 70  ? -41.43627 29.77751 -7.89764  1.000 25.82577 ? 69  ASN A CG  1 
ATOM   546  O OD1 . ASN A 1 70  ? -42.50968 29.29220 -8.26176  1.000 22.29108 ? 69  ASN A OD1 1 
ATOM   547  N ND2 . ASN A 1 70  ? -40.33951 29.04388 -7.71116  1.000 22.07535 ? 69  ASN A ND2 1 
ATOM   548  N N   . SER A 1 71  ? -40.58878 34.39870 -8.66302  1.000 25.70428 ? 70  SER A N   1 
ATOM   549  C CA  . SER A 1 71  ? -40.61740 35.70414 -8.01685  1.000 25.31911 ? 70  SER A CA  1 
ATOM   550  C C   . SER A 1 71  ? -40.87172 36.80485 -9.03910  1.000 22.43816 ? 70  SER A C   1 
ATOM   551  O O   . SER A 1 71  ? -40.02075 37.04571 -9.90407  1.000 22.48470 ? 70  SER A O   1 
ATOM   552  C CB  . SER A 1 71  ? -39.29936 35.94285 -7.28118  1.000 20.64087 ? 70  SER A CB  1 
ATOM   553  O OG  . SER A 1 71  ? -39.06007 37.30742 -7.01902  1.000 20.73796 ? 70  SER A OG  1 
ATOM   554  N N   . PRO A 1 72  ? -42.01658 37.47706 -8.99507  1.000 23.50009 ? 71  PRO A N   1 
ATOM   555  C CA  . PRO A 1 72  ? -42.21677 38.65057 -9.86535  1.000 22.55438 ? 71  PRO A CA  1 
ATOM   556  C C   . PRO A 1 72  ? -41.11231 39.68455 -9.74253  1.000 21.87716 ? 71  PRO A C   1 
ATOM   557  O O   . PRO A 1 72  ? -40.70552 40.26678 -10.75082 1.000 22.75539 ? 71  PRO A O   1 
ATOM   558  C CB  . PRO A 1 72  ? -43.56139 39.21892 -9.39435  1.000 24.74590 ? 71  PRO A CB  1 
ATOM   559  C CG  . PRO A 1 72  ? -44.20678 38.14071 -8.63227  1.000 26.53216 ? 71  PRO A CG  1 
ATOM   560  C CD  . PRO A 1 72  ? -43.14759 37.23282 -8.08827  1.000 23.73919 ? 71  PRO A CD  1 
ATOM   561  N N   . ILE A 1 73  ? -40.59533 39.91367 -8.53591  1.000 20.71845 ? 72  ILE A N   1 
ATOM   562  C CA  . ILE A 1 73  ? -39.53575 40.90754 -8.37022  1.000 22.12080 ? 72  ILE A CA  1 
ATOM   563  C C   . ILE A 1 73  ? -38.28701 40.49116 -9.13865  1.000 23.87536 ? 72  ILE A C   1 
ATOM   564  O O   . ILE A 1 73  ? -37.68892 41.29303 -9.86548  1.000 21.76045 ? 72  ILE A O   1 
ATOM   565  C CB  . ILE A 1 73  ? -39.22629 41.12982 -6.88007  1.000 24.09076 ? 72  ILE A CB  1 
ATOM   566  C CG1 . ILE A 1 73  ? -40.39582 41.84232 -6.19219  1.000 24.58472 ? 72  ILE A CG1 1 
ATOM   567  C CG2 . ILE A 1 73  ? -37.95623 41.94570 -6.73084  1.000 23.95490 ? 72  ILE A CG2 1 
ATOM   568  C CD1 . ILE A 1 73  ? -40.28657 41.88305 -4.67323  1.000 24.84701 ? 72  ILE A CD1 1 
ATOM   569  N N   . PHE A 1 74  ? -37.86451 39.23247 -8.98128  1.000 20.93225 ? 73  PHE A N   1 
ATOM   570  C CA  . PHE A 1 74  ? -36.70446 38.75476 -9.72922  1.000 20.97180 ? 73  PHE A CA  1 
ATOM   571  C C   . PHE A 1 74  ? -36.91835 38.89670 -11.23415 1.000 22.50864 ? 73  PHE A C   1 
ATOM   572  O O   . PHE A 1 74  ? -36.01350 39.31636 -11.96510 1.000 23.03039 ? 73  PHE A O   1 
ATOM   573  C CB  . PHE A 1 74  ? -36.41344 37.29534 -9.35997  1.000 23.10612 ? 73  PHE A CB  1 
ATOM   574  C CG  . PHE A 1 74  ? -35.22132 36.70958 -10.08039 1.000 24.64341 ? 73  PHE A CG  1 
ATOM   575  C CD1 . PHE A 1 74  ? -33.94169 36.82709 -9.54340  1.000 23.76447 ? 73  PHE A CD1 1 
ATOM   576  C CD2 . PHE A 1 74  ? -35.37993 36.03843 -11.29177 1.000 23.67846 ? 73  PHE A CD2 1 
ATOM   577  C CE1 . PHE A 1 74  ? -32.84171 36.28331 -10.20125 1.000 24.95894 ? 73  PHE A CE1 1 
ATOM   578  C CE2 . PHE A 1 74  ? -34.28701 35.49580 -11.95612 1.000 23.35018 ? 73  PHE A CE2 1 
ATOM   579  C CZ  . PHE A 1 74  ? -33.01467 35.61678 -11.40554 1.000 23.21691 ? 73  PHE A CZ  1 
ATOM   580  N N   . LEU A 1 75  ? -38.11536 38.56555 -11.71531 1.000 20.07330 ? 74  LEU A N   1 
ATOM   581  C CA  . LEU A 1 75  ? -38.34943 38.56520 -13.15098 1.000 22.25465 ? 74  LEU A CA  1 
ATOM   582  C C   . LEU A 1 75  ? -38.32550 39.96592 -13.75184 1.000 24.05214 ? 74  LEU A C   1 
ATOM   583  O O   . LEU A 1 75  ? -38.15806 40.08533 -14.97100 1.000 21.04948 ? 74  LEU A O   1 
ATOM   584  C CB  . LEU A 1 75  ? -39.67608 37.87276 -13.45900 1.000 19.64481 ? 74  LEU A CB  1 
ATOM   585  C CG  . LEU A 1 75  ? -39.65507 36.35096 -13.27208 1.000 25.51443 ? 74  LEU A CG  1 
ATOM   586  C CD1 . LEU A 1 75  ? -41.06304 35.79637 -13.30566 1.000 22.64219 ? 74  LEU A CD1 1 
ATOM   587  C CD2 . LEU A 1 75  ? -38.79653 35.66946 -14.34641 1.000 23.81468 ? 74  LEU A CD2 1 
ATOM   588  N N   . ARG A 1 76  ? -38.47579 41.02245 -12.93235 1.000 22.90963 ? 75  ARG A N   1 
ATOM   589  C CA  . ARG A 1 76  ? -38.40740 42.38358 -13.46434 1.000 27.33669 ? 75  ARG A CA  1 
ATOM   590  C C   . ARG A 1 76  ? -37.14575 42.60030 -14.28411 1.000 24.76996 ? 75  ARG A C   1 
ATOM   591  O O   . ARG A 1 76  ? -37.15443 43.38631 -15.23921 1.000 25.06713 ? 75  ARG A O   1 
ATOM   592  C CB  . ARG A 1 76  ? -38.45247 43.43302 -12.34182 1.000 23.55421 ? 75  ARG A CB  1 
ATOM   593  C CG  . ARG A 1 76  ? -39.82553 43.69101 -11.74525 1.000 30.13122 ? 75  ARG A CG  1 
ATOM   594  C CD  . ARG A 1 76  ? -40.89172 43.93983 -12.82419 1.000 32.05227 ? 75  ARG A CD  1 
ATOM   595  N NE  . ARG A 1 76  ? -40.51352 44.98682 -13.77082 1.000 24.90965 ? 75  ARG A NE  1 
ATOM   596  C CZ  . ARG A 1 76  ? -41.34551 45.53362 -14.65190 1.000 30.90083 ? 75  ARG A CZ  1 
ATOM   597  N NH1 . ARG A 1 76  ? -42.60764 45.14891 -14.74282 1.000 26.33320 ? 75  ARG A NH1 1 
ATOM   598  N NH2 . ARG A 1 76  ? -40.89747 46.48947 -15.46716 1.000 27.52513 ? 75  ARG A NH2 1 
ATOM   599  N N   . ARG A 1 77  ? -36.05734 41.90686 -13.93610 1.000 20.02418 ? 76  ARG A N   1 
ATOM   600  C CA  . ARG A 1 77  ? -34.79740 42.09189 -14.64518 1.000 25.72187 ? 76  ARG A CA  1 
ATOM   601  C C   . ARG A 1 77  ? -34.85137 41.58705 -16.08547 1.000 27.73356 ? 76  ARG A C   1 
ATOM   602  O O   . ARG A 1 77  ? -33.95901 41.91493 -16.87749 1.000 25.45523 ? 76  ARG A O   1 
ATOM   603  C CB  . ARG A 1 77  ? -33.66149 41.40363 -13.88487 1.000 24.94635 ? 76  ARG A CB  1 
ATOM   604  C CG  . ARG A 1 77  ? -33.57807 39.90597 -14.11597 1.000 27.17028 ? 76  ARG A CG  1 
ATOM   605  C CD  . ARG A 1 77  ? -32.67492 39.25469 -13.06477 1.000 25.58283 ? 76  ARG A CD  1 
ATOM   606  N NE  . ARG A 1 77  ? -33.08612 39.62728 -11.71544 1.000 23.87311 ? 76  ARG A NE  1 
ATOM   607  C CZ  . ARG A 1 77  ? -32.28845 39.63515 -10.65651 1.000 24.10049 ? 76  ARG A CZ  1 
ATOM   608  N NH1 . ARG A 1 77  ? -31.01406 39.28251 -10.74672 1.000 19.08196 ? 76  ARG A NH1 1 
ATOM   609  N NH2 . ARG A 1 77  ? -32.78173 40.01217 -9.47729  1.000 21.30179 ? 76  ARG A NH2 1 
ATOM   610  N N   . PHE A 1 78  ? -35.86599 40.80507 -16.44986 1.000 24.27634 ? 77  PHE A N   1 
ATOM   611  C CA  . PHE A 1 78  ? -36.04410 40.39051 -17.83204 1.000 23.73517 ? 77  PHE A CA  1 
ATOM   612  C C   . PHE A 1 78  ? -37.12653 41.19100 -18.52853 1.000 24.29097 ? 77  PHE A C   1 
ATOM   613  O O   . PHE A 1 78  ? -37.43550 40.91650 -19.69166 1.000 25.81252 ? 77  PHE A O   1 
ATOM   614  C CB  . PHE A 1 78  ? -36.38563 38.89600 -17.90623 1.000 21.43677 ? 77  PHE A CB  1 
ATOM   615  C CG  . PHE A 1 78  ? -35.37966 38.01475 -17.22921 1.000 23.45773 ? 77  PHE A CG  1 
ATOM   616  C CD1 . PHE A 1 78  ? -34.11527 37.84320 -17.77483 1.000 21.55036 ? 77  PHE A CD1 1 
ATOM   617  C CD2 . PHE A 1 78  ? -35.68904 37.36760 -16.03300 1.000 25.19881 ? 77  PHE A CD2 1 
ATOM   618  C CE1 . PHE A 1 78  ? -33.16825 37.03437 -17.14661 1.000 23.26759 ? 77  PHE A CE1 1 
ATOM   619  C CE2 . PHE A 1 78  ? -34.74763 36.54744 -15.40019 1.000 24.82997 ? 77  PHE A CE2 1 
ATOM   620  C CZ  . PHE A 1 78  ? -33.47853 36.38811 -15.96546 1.000 20.35222 ? 77  PHE A CZ  1 
ATOM   621  N N   . SER A 1 79  ? -37.71713 42.17388 -17.84599 1.000 24.54916 ? 78  SER A N   1 
ATOM   622  C CA  . SER A 1 79  ? -38.91763 42.82379 -18.37077 1.000 25.04683 ? 78  SER A CA  1 
ATOM   623  C C   . SER A 1 79  ? -38.65203 43.50489 -19.71560 1.000 26.55151 ? 78  SER A C   1 
ATOM   624  O O   . SER A 1 79  ? -39.52883 43.55500 -20.57908 1.000 27.72419 ? 78  SER A O   1 
ATOM   625  C CB  . SER A 1 79  ? -39.45810 43.81909 -17.33597 1.000 27.36630 ? 78  SER A CB  1 
ATOM   626  O OG  . SER A 1 79  ? -38.71245 45.02766 -17.32572 1.000 28.89890 ? 78  SER A OG  1 
ATOM   627  N N   . ALA A 1 80  ? -37.43972 44.01206 -19.92321 1.000 27.64903 ? 79  ALA A N   1 
ATOM   628  C CA  . ALA A 1 80  ? -37.12264 44.76413 -21.13437 1.000 31.58175 ? 79  ALA A CA  1 
ATOM   629  C C   . ALA A 1 80  ? -36.42378 43.92486 -22.19400 1.000 31.22342 ? 79  ALA A C   1 
ATOM   630  O O   . ALA A 1 80  ? -35.93277 44.47648 -23.18438 1.000 31.15591 ? 79  ALA A O   1 
ATOM   631  C CB  . ALA A 1 80  ? -36.24797 45.97068 -20.79281 1.000 26.99896 ? 79  ALA A CB  1 
ATOM   632  N N   . CYS A 1 81  ? -36.36227 42.60747 -22.01719 1.000 25.82144 ? 80  CYS A N   1 
ATOM   633  C CA  . CYS A 1 81  ? -35.58090 41.78217 -22.92491 1.000 27.35587 ? 80  CYS A CA  1 
ATOM   634  C C   . CYS A 1 81  ? -36.08418 40.34257 -22.92522 1.000 26.23968 ? 80  CYS A C   1 
ATOM   635  O O   . CYS A 1 81  ? -35.29272 39.39639 -22.92282 1.000 24.83759 ? 80  CYS A O   1 
ATOM   636  C CB  . CYS A 1 81  ? -34.09147 41.84151 -22.56471 1.000 26.50326 ? 80  CYS A CB  1 
ATOM   637  S SG  . CYS A 1 81  ? -33.71807 41.11400 -20.93621 1.000 23.71218 ? 80  CYS A SG  1 
ATOM   638  N N   . SER A 1 82  ? -37.40600 40.15580 -22.97306 1.000 24.39899 ? 81  SER A N   1 
ATOM   639  C CA  . SER A 1 82  ? -37.98358 38.81699 -22.99562 1.000 24.72162 ? 81  SER A CA  1 
ATOM   640  C C   . SER A 1 82  ? -39.45379 38.94448 -23.36888 1.000 25.45837 ? 81  SER A C   1 
ATOM   641  O O   . SER A 1 82  ? -40.00143 40.04739 -23.44692 1.000 26.99663 ? 81  SER A O   1 
ATOM   642  C CB  . SER A 1 82  ? -37.79629 38.10717 -21.63890 1.000 23.44631 ? 81  SER A CB  1 
ATOM   643  O OG  . SER A 1 82  ? -38.64831 38.68734 -20.64914 1.000 23.78728 ? 81  SER A OG  1 
ATOM   644  N N   . VAL A 1 83  ? -40.10086 37.80042 -23.57169 1.000 21.58797 ? 82  VAL A N   1 
ATOM   645  C CA  . VAL A 1 83  ? -41.53810 37.75264 -23.81087 1.000 22.11842 ? 82  VAL A CA  1 
ATOM   646  C C   . VAL A 1 83  ? -42.16463 36.77640 -22.82189 1.000 24.67263 ? 82  VAL A C   1 
ATOM   647  O O   . VAL A 1 83  ? -41.69016 35.64603 -22.66649 1.000 21.16969 ? 82  VAL A O   1 
ATOM   648  C CB  . VAL A 1 83  ? -41.87691 37.34649 -25.25712 1.000 28.45962 ? 82  VAL A CB  1 
ATOM   649  C CG1 . VAL A 1 83  ? -43.39624 37.22254 -25.41836 1.000 22.75684 ? 82  VAL A CG1 1 
ATOM   650  C CG2 . VAL A 1 83  ? -41.31041 38.37687 -26.26661 1.000 25.96493 ? 82  VAL A CG2 1 
ATOM   651  N N   . GLY A 1 84  ? -43.21234 37.21562 -22.13887 1.000 24.90629 ? 83  GLY A N   1 
ATOM   652  C CA  . GLY A 1 84  ? -44.00605 36.32539 -21.32972 1.000 21.18770 ? 83  GLY A CA  1 
ATOM   653  C C   . GLY A 1 84  ? -43.66602 36.27766 -19.85931 1.000 21.38320 ? 83  GLY A C   1 
ATOM   654  O O   . GLY A 1 84  ? -44.18805 35.40687 -19.15484 1.000 22.29915 ? 83  GLY A O   1 
ATOM   655  N N   . PHE A 1 85  ? -42.83409 37.19613 -19.36364 1.000 21.63548 ? 84  PHE A N   1 
ATOM   656  C CA  . PHE A 1 85  ? -42.40840 37.12233 -17.96988 1.000 22.10082 ? 84  PHE A CA  1 
ATOM   657  C C   . PHE A 1 85  ? -43.57828 37.30242 -17.00015 1.000 21.72527 ? 84  PHE A C   1 
ATOM   658  O O   . PHE A 1 85  ? -43.53527 36.78114 -15.88180 1.000 19.52278 ? 84  PHE A O   1 
ATOM   659  C CB  . PHE A 1 85  ? -41.31745 38.16218 -17.71248 1.000 22.93360 ? 84  PHE A CB  1 
ATOM   660  C CG  . PHE A 1 85  ? -41.84047 39.55935 -17.50070 1.000 22.68211 ? 84  PHE A CG  1 
ATOM   661  C CD1 . PHE A 1 85  ? -42.13729 40.37404 -18.58296 1.000 24.67644 ? 84  PHE A CD1 1 
ATOM   662  C CD2 . PHE A 1 85  ? -42.02541 40.05707 -16.22285 1.000 21.64198 ? 84  PHE A CD2 1 
ATOM   663  C CE1 . PHE A 1 85  ? -42.62399 41.66492 -18.39577 1.000 26.21734 ? 84  PHE A CE1 1 
ATOM   664  C CE2 . PHE A 1 85  ? -42.50038 41.35232 -16.02167 1.000 26.54004 ? 84  PHE A CE2 1 
ATOM   665  C CZ  . PHE A 1 85  ? -42.79853 42.15993 -17.11720 1.000 24.11029 ? 84  PHE A CZ  1 
ATOM   666  N N   . GLU A 1 86  ? -44.63220 38.02047 -17.40933 1.000 21.40127 ? 85  GLU A N   1 
ATOM   667  C CA  . GLU A 1 86  ? -45.76038 38.26728 -16.51080 1.000 22.61329 ? 85  GLU A CA  1 
ATOM   668  C C   . GLU A 1 86  ? -46.49042 36.98246 -16.14881 1.000 23.18795 ? 85  GLU A C   1 
ATOM   669  O O   . GLU A 1 86  ? -47.14210 36.91440 -15.09442 1.000 22.38470 ? 85  GLU A O   1 
ATOM   670  C CB  . GLU A 1 86  ? -46.74869 39.25357 -17.14389 1.000 25.47230 ? 85  GLU A CB  1 
ATOM   671  C CG  . GLU A 1 86  ? -46.17804 40.62886 -17.44965 1.000 22.52934 ? 85  GLU A CG  1 
ATOM   672  C CD  . GLU A 1 86  ? -45.73620 40.76952 -18.89327 1.000 28.49525 ? 85  GLU A CD  1 
ATOM   673  O OE1 . GLU A 1 86  ? -45.34521 39.75126 -19.50453 1.000 25.68813 ? 85  GLU A OE1 1 
ATOM   674  O OE2 . GLU A 1 86  ? -45.76585 41.90198 -19.41319 1.000 25.44303 ? 85  GLU A OE2 1 
ATOM   675  N N   . GLU A 1 87  ? -46.40802 35.96248 -17.00828 1.000 22.16559 ? 86  GLU A N   1 
ATOM   676  C CA  . GLU A 1 87  ? -47.11437 34.70158 -16.80844 1.000 24.53961 ? 86  GLU A CA  1 
ATOM   677  C C   . GLU A 1 87  ? -46.24624 33.61309 -16.18395 1.000 23.54996 ? 86  GLU A C   1 
ATOM   678  O O   . GLU A 1 87  ? -46.76002 32.53230 -15.86668 1.000 21.67236 ? 86  GLU A O   1 
ATOM   679  C CB  . GLU A 1 87  ? -47.67580 34.18895 -18.14931 1.000 23.74582 ? 86  GLU A CB  1 
ATOM   680  C CG  . GLU A 1 87  ? -48.72167 35.08770 -18.81591 1.000 25.32079 ? 86  GLU A CG  1 
ATOM   681  C CD  . GLU A 1 87  ? -50.09500 35.03462 -18.13231 1.000 34.23527 ? 86  GLU A CD  1 
ATOM   682  O OE1 . GLU A 1 87  ? -50.29880 34.19606 -17.21292 1.000 33.60581 ? 86  GLU A OE1 1 
ATOM   683  O OE2 . GLU A 1 87  ? -50.98745 35.81393 -18.54384 1.000 32.01667 ? 86  GLU A OE2 1 
ATOM   684  N N   . ILE A 1 88  ? -44.95487 33.85956 -16.00152 1.000 21.53182 ? 87  ILE A N   1 
ATOM   685  C CA  . ILE A 1 88  ? -44.03969 32.80161 -15.57975 1.000 22.07464 ? 87  ILE A CA  1 
ATOM   686  C C   . ILE A 1 88  ? -44.29777 32.36164 -14.13746 1.000 21.28480 ? 87  ILE A C   1 
ATOM   687  O O   . ILE A 1 88  ? -44.29911 31.14842 -13.88192 1.000 18.77174 ? 87  ILE A O   1 
ATOM   688  C CB  . ILE A 1 88  ? -42.58051 33.22685 -15.82628 1.000 24.87021 ? 87  ILE A CB  1 
ATOM   689  C CG1 . ILE A 1 88  ? -42.26925 33.15618 -17.32830 1.000 23.35186 ? 87  ILE A CG1 1 
ATOM   690  C CG2 . ILE A 1 88  ? -41.59431 32.36464 -15.05129 1.000 23.51137 ? 87  ILE A CG2 1 
ATOM   691  C CD1 . ILE A 1 88  ? -42.36811 31.73990 -17.92881 1.000 18.71626 ? 87  ILE A CD1 1 
ATOM   692  N N   . PRO A 1 89  ? -44.53812 33.25132 -13.15894 1.000 24.44673 ? 88  PRO A N   1 
ATOM   693  C CA  . PRO A 1 89  ? -44.90921 32.73120 -11.82677 1.000 23.60050 ? 88  PRO A CA  1 
ATOM   694  C C   . PRO A 1 89  ? -46.12925 31.82062 -11.86660 1.000 21.83940 ? 88  PRO A C   1 
ATOM   695  O O   . PRO A 1 89  ? -46.10882 30.74899 -11.24799 1.000 20.56637 ? 88  PRO A O   1 
ATOM   696  C CB  . PRO A 1 89  ? -45.15881 34.00427 -11.00659 1.000 21.16218 ? 88  PRO A CB  1 
ATOM   697  C CG  . PRO A 1 89  ? -44.24671 35.00747 -11.63940 1.000 21.42897 ? 88  PRO A CG  1 
ATOM   698  C CD  . PRO A 1 89  ? -44.39530 34.71930 -13.12518 1.000 20.15407 ? 88  PRO A CD  1 
ATOM   699  N N   . THR A 1 90  ? -47.17416 32.19891 -12.60914 1.000 19.26092 ? 89  THR A N   1 
ATOM   700  C CA  . THR A 1 90  ? -48.32115 31.31270 -12.80800 1.000 19.92844 ? 89  THR A CA  1 
ATOM   701  C C   . THR A 1 90  ? -47.88455 29.98531 -13.43687 1.000 22.88838 ? 89  THR A C   1 
ATOM   702  O O   . THR A 1 90  ? -48.28615 28.90649 -12.98513 1.000 20.07811 ? 89  THR A O   1 
ATOM   703  C CB  . THR A 1 90  ? -49.37249 32.02011 -13.68490 1.000 25.67297 ? 89  THR A CB  1 
ATOM   704  O OG1 . THR A 1 90  ? -49.82393 33.22226 -13.04491 1.000 20.42798 ? 89  THR A OG1 1 
ATOM   705  C CG2 . THR A 1 90  ? -50.58758 31.10913 -13.98078 1.000 26.45468 ? 89  THR A CG2 1 
ATOM   706  N N   . ALA A 1 91  ? -47.05121 30.04534 -14.48523 1.000 20.30843 ? 90  ALA A N   1 
ATOM   707  C CA  . ALA A 1 91  ? -46.57031 28.81516 -15.11117 1.000 20.59862 ? 90  ALA A CA  1 
ATOM   708  C C   . ALA A 1 91  ? -45.87397 27.90947 -14.09787 1.000 21.50749 ? 90  ALA A C   1 
ATOM   709  O O   . ALA A 1 91  ? -46.07058 26.68796 -14.10674 1.000 22.50962 ? 90  ALA A O   1 
ATOM   710  C CB  . ALA A 1 91  ? -45.63057 29.14229 -16.27802 1.000 19.85723 ? 90  ALA A CB  1 
ATOM   711  N N   . LEU A 1 92  ? -45.07233 28.48587 -13.20334 1.000 19.72307 ? 91  LEU A N   1 
ATOM   712  C CA  . LEU A 1 92  ? -44.36055 27.65693 -12.23352 1.000 22.31028 ? 91  LEU A CA  1 
ATOM   713  C C   . LEU A 1 92  ? -45.30693 27.04343 -11.20442 1.000 22.44583 ? 91  LEU A C   1 
ATOM   714  O O   . LEU A 1 92  ? -45.10811 25.89200 -10.79059 1.000 21.99587 ? 91  LEU A O   1 
ATOM   715  C CB  . LEU A 1 92  ? -43.26041 28.46881 -11.54795 1.000 22.35011 ? 91  LEU A CB  1 
ATOM   716  C CG  . LEU A 1 92  ? -41.87350 28.10404 -12.09591 1.000 24.10886 ? 91  LEU A CG  1 
ATOM   717  C CD1 . LEU A 1 92  ? -41.65114 28.71221 -13.46725 1.000 21.12265 ? 91  LEU A CD1 1 
ATOM   718  C CD2 . LEU A 1 92  ? -40.79486 28.53956 -11.14107 1.000 27.85762 ? 91  LEU A CD2 1 
ATOM   719  N N   . GLN A 1 93  ? -46.33390 27.78702 -10.77028 1.000 21.67349 ? 92  GLN A N   1 
ATOM   720  C CA  . GLN A 1 93  ? -47.35832 27.18433 -9.91933  1.000 24.31254 ? 92  GLN A CA  1 
ATOM   721  C C   . GLN A 1 93  ? -47.95569 25.96079 -10.59263 1.000 23.21250 ? 92  GLN A C   1 
ATOM   722  O O   . GLN A 1 93  ? -48.07387 24.89638 -9.97858  1.000 19.87873 ? 92  GLN A O   1 
ATOM   723  C CB  . GLN A 1 93  ? -48.46289 28.19064 -9.59696  1.000 24.74023 ? 92  GLN A CB  1 
ATOM   724  C CG  . GLN A 1 93  ? -48.07412 29.28834 -8.60753  1.000 31.44882 ? 92  GLN A CG  1 
ATOM   725  C CD  . GLN A 1 93  ? -47.75209 28.74670 -7.23254  1.000 42.69648 ? 92  GLN A CD  1 
ATOM   726  O OE1 . GLN A 1 93  ? -48.28608 27.70624 -6.82663  1.000 45.86844 ? 92  GLN A OE1 1 
ATOM   727  N NE2 . GLN A 1 93  ? -46.87453 29.44836 -6.49723  1.000 40.64500 ? 92  GLN A NE2 1 
ATOM   728  N N   . ARG A 1 94  ? -48.31624 26.09308 -11.87419 1.000 23.09606 ? 93  ARG A N   1 
ATOM   729  C CA  . ARG A 1 94  ? -48.92916 24.98567 -12.59853 1.000 25.11731 ? 93  ARG A CA  1 
ATOM   730  C C   . ARG A 1 94  ? -47.97006 23.80479 -12.71015 1.000 22.00669 ? 93  ARG A C   1 
ATOM   731  O O   . ARG A 1 94  ? -48.34631 22.65697 -12.44571 1.000 21.46567 ? 93  ARG A O   1 
ATOM   732  C CB  . ARG A 1 94  ? -49.38050 25.46557 -13.98487 1.000 21.92232 ? 93  ARG A CB  1 
ATOM   733  C CG  . ARG A 1 94  ? -50.28060 24.49453 -14.74427 1.000 22.50536 ? 93  ARG A CG  1 
ATOM   734  C CD  . ARG A 1 94  ? -50.56392 25.00873 -16.16870 1.000 26.38734 ? 93  ARG A CD  1 
ATOM   735  N NE  . ARG A 1 94  ? -49.33109 25.33476 -16.88041 1.000 24.90115 ? 93  ARG A NE  1 
ATOM   736  C CZ  . ARG A 1 94  ? -48.94205 26.55991 -17.21350 1.000 26.09825 ? 93  ARG A CZ  1 
ATOM   737  N NH1 . ARG A 1 94  ? -49.68099 27.62368 -16.93736 1.000 25.25741 ? 93  ARG A NH1 1 
ATOM   738  N NH2 . ARG A 1 94  ? -47.78196 26.72202 -17.84215 1.000 25.05896 ? 93  ARG A NH2 1 
ATOM   739  N N   . ILE A 1 95  ? -46.71971 24.07014 -13.09135 1.000 21.71834 ? 94  ILE A N   1 
ATOM   740  C CA  . ILE A 1 95  ? -45.75703 22.98460 -13.27177 1.000 24.15461 ? 94  ILE A CA  1 
ATOM   741  C C   . ILE A 1 95  ? -45.48534 22.28657 -11.94406 1.000 24.47339 ? 94  ILE A C   1 
ATOM   742  O O   . ILE A 1 95  ? -45.43662 21.04833 -11.87552 1.000 22.66487 ? 94  ILE A O   1 
ATOM   743  C CB  . ILE A 1 95  ? -44.45673 23.51204 -13.90824 1.000 20.69179 ? 94  ILE A CB  1 
ATOM   744  C CG1 . ILE A 1 95  ? -44.67052 23.83328 -15.38736 1.000 21.53191 ? 94  ILE A CG1 1 
ATOM   745  C CG2 . ILE A 1 95  ? -43.33426 22.47662 -13.77618 1.000 20.73180 ? 94  ILE A CG2 1 
ATOM   746  C CD1 . ILE A 1 95  ? -43.65785 24.82156 -15.92915 1.000 24.32538 ? 94  ILE A CD1 1 
ATOM   747  N N   . ARG A 1 96  ? -45.30419 23.06734 -10.87174 1.000 20.45467 ? 95  ARG A N   1 
ATOM   748  C CA  . ARG A 1 96  ? -45.14911 22.48627 -9.54142  1.000 24.70271 ? 95  ARG A CA  1 
ATOM   749  C C   . ARG A 1 96  ? -46.34844 21.61625 -9.17254  1.000 23.91529 ? 95  ARG A C   1 
ATOM   750  O O   . ARG A 1 96  ? -46.19221 20.51832 -8.62700  1.000 22.87008 ? 95  ARG A O   1 
ATOM   751  C CB  . ARG A 1 96  ? -44.96166 23.59919 -8.51467  1.000 21.34346 ? 95  ARG A CB  1 
ATOM   752  C CG  . ARG A 1 96  ? -43.52235 24.06761 -8.37770  1.000 25.99206 ? 95  ARG A CG  1 
ATOM   753  C CD  . ARG A 1 96  ? -43.45958 25.48425 -7.81731  1.000 21.96014 ? 95  ARG A CD  1 
ATOM   754  N NE  . ARG A 1 96  ? -43.90486 25.53756 -6.43018  1.000 26.83386 ? 95  ARG A NE  1 
ATOM   755  C CZ  . ARG A 1 96  ? -44.09340 26.66260 -5.75467  1.000 30.04014 ? 95  ARG A CZ  1 
ATOM   756  N NH1 . ARG A 1 96  ? -43.86082 27.84631 -6.30458  1.000 30.30786 ? 95  ARG A NH1 1 
ATOM   757  N NH2 . ARG A 1 96  ? -44.53426 26.60087 -4.50170  1.000 27.73646 ? 95  ARG A NH2 1 
ATOM   758  N N   . SER A 1 97  ? -47.55301 22.08998 -9.46700  1.000 20.69869 ? 96  SER A N   1 
ATOM   759  C CA  . SER A 1 97  ? -48.74206 21.31925 -9.14702  1.000 25.88225 ? 96  SER A CA  1 
ATOM   760  C C   . SER A 1 97  ? -48.80820 20.02569 -9.95952  1.000 25.36661 ? 96  SER A C   1 
ATOM   761  O O   . SER A 1 97  ? -49.19946 18.97849 -9.43031  1.000 22.01875 ? 96  SER A O   1 
ATOM   762  C CB  . SER A 1 97  ? -49.97516 22.19808 -9.36142  1.000 26.63397 ? 96  SER A CB  1 
ATOM   763  O OG  . SER A 1 97  ? -51.07138 21.43119 -9.80484  1.000 37.36731 ? 96  SER A OG  1 
ATOM   764  N N   . VAL A 1 98  ? -48.40498 20.06959 -11.23748 1.000 22.72736 ? 97  VAL A N   1 
ATOM   765  C CA  . VAL A 1 98  ? -48.46132 18.87765 -12.08455 1.000 21.05832 ? 97  VAL A CA  1 
ATOM   766  C C   . VAL A 1 98  ? -47.38315 17.87604 -11.67465 1.000 23.77480 ? 97  VAL A C   1 
ATOM   767  O O   . VAL A 1 98  ? -47.64504 16.67178 -11.54587 1.000 19.37878 ? 97  VAL A O   1 
ATOM   768  C CB  . VAL A 1 98  ? -48.32040 19.25981 -13.57118 1.000 20.88284 ? 97  VAL A CB  1 
ATOM   769  C CG1 . VAL A 1 98  ? -48.16845 18.00006 -14.44219 1.000 21.70863 ? 97  VAL A CG1 1 
ATOM   770  C CG2 . VAL A 1 98  ? -49.49345 20.12945 -14.04089 1.000 21.49380 ? 97  VAL A CG2 1 
ATOM   771  N N   . TYR A 1 99  ? -46.14528 18.35439 -11.49310 1.000 22.28642 ? 98  TYR A N   1 
ATOM   772  C CA  . TYR A 1 99  ? -45.04925 17.45249 -11.15044 1.000 23.11984 ? 98  TYR A CA  1 
ATOM   773  C C   . TYR A 1 99  ? -45.22906 16.87020 -9.75569  1.000 24.31428 ? 98  TYR A C   1 
ATOM   774  O O   . TYR A 1 99  ? -44.95073 15.68521 -9.53257  1.000 24.24221 ? 98  TYR A O   1 
ATOM   775  C CB  . TYR A 1 99  ? -43.69974 18.17261 -11.25538 1.000 24.22913 ? 98  TYR A CB  1 
ATOM   776  C CG  . TYR A 1 99  ? -42.52076 17.25173 -11.04347 1.000 24.71739 ? 98  TYR A CG  1 
ATOM   777  C CD1 . TYR A 1 99  ? -42.23962 16.22495 -11.94832 1.000 25.18463 ? 98  TYR A CD1 1 
ATOM   778  C CD2 . TYR A 1 99  ? -41.71295 17.37747 -9.92693  1.000 23.08285 ? 98  TYR A CD2 1 
ATOM   779  C CE1 . TYR A 1 99  ? -41.17923 15.36706 -11.74231 1.000 23.96516 ? 98  TYR A CE1 1 
ATOM   780  C CE2 . TYR A 1 99  ? -40.63874 16.53628 -9.72556  1.000 24.20270 ? 98  TYR A CE2 1 
ATOM   781  C CZ  . TYR A 1 99  ? -40.37544 15.53519 -10.62232 1.000 27.80499 ? 98  TYR A CZ  1 
ATOM   782  O OH  . TYR A 1 99  ? -39.30466 14.69406 -10.39875 1.000 25.83893 ? 98  TYR A OH  1 
ATOM   783  N N   . THR A 1 100 ? -45.68764 17.68304 -8.80183  1.000 22.30744 ? 99  THR A N   1 
ATOM   784  C CA  . THR A 1 100 ? -45.97975 17.15435 -7.47317  1.000 22.63435 ? 99  THR A CA  1 
ATOM   785  C C   . THR A 1 100 ? -46.99840 16.02191 -7.55345  1.000 26.58443 ? 99  THR A C   1 
ATOM   786  O O   . THR A 1 100 ? -46.81014 14.95634 -6.94434  1.000 24.14233 ? 99  THR A O   1 
ATOM   787  C CB  . THR A 1 100 ? -46.47542 18.27864 -6.55564  1.000 24.08015 ? 99  THR A CB  1 
ATOM   788  O OG1 . THR A 1 100 ? -45.40570 19.21793 -6.32461  1.000 20.32438 ? 99  THR A OG1 1 
ATOM   789  C CG2 . THR A 1 100 ? -46.97829 17.72387 -5.21730  1.000 23.28808 ? 99  THR A CG2 1 
ATOM   790  N N   . ALA A 1 101 ? -48.08424 16.22850 -8.31672  1.000 19.37150 ? 100 ALA A N   1 
ATOM   791  C CA  . ALA A 1 101 ? -49.12126 15.20429 -8.40540  1.000 23.82714 ? 100 ALA A CA  1 
ATOM   792  C C   . ALA A 1 101 ? -48.57861 13.93985 -9.04606  1.000 25.05611 ? 100 ALA A C   1 
ATOM   793  O O   . ALA A 1 101 ? -48.94434 12.82300 -8.65493  1.000 22.97077 ? 100 ALA A O   1 
ATOM   794  C CB  . ALA A 1 101 ? -50.32293 15.71256 -9.19905  1.000 20.54212 ? 100 ALA A CB  1 
ATOM   795  N N   . LYS A 1 102 ? -47.71120 14.09802 -10.04308 1.000 23.61234 ? 101 LYS A N   1 
ATOM   796  C CA  . LYS A 1 102 ? -47.13536 12.93727 -10.70326 1.000 24.24038 ? 101 LYS A CA  1 
ATOM   797  C C   . LYS A 1 102 ? -46.29993 12.11395 -9.72892  1.000 26.58792 ? 101 LYS A C   1 
ATOM   798  O O   . LYS A 1 102 ? -46.41820 10.88491 -9.68747  1.000 26.44769 ? 101 LYS A O   1 
ATOM   799  C CB  . LYS A 1 102 ? -46.31623 13.39908 -11.90493 1.000 23.32171 ? 101 LYS A CB  1 
ATOM   800  C CG  . LYS A 1 102 ? -45.62081 12.30246 -12.66862 1.000 28.28156 ? 101 LYS A CG  1 
ATOM   801  C CD  . LYS A 1 102 ? -44.97264 12.85950 -13.92851 1.000 26.22423 ? 101 LYS A CD  1 
ATOM   802  C CE  . LYS A 1 102 ? -44.35776 11.75454 -14.77490 1.000 27.79526 ? 101 LYS A CE  1 
ATOM   803  N NZ  . LYS A 1 102 ? -43.83070 12.28933 -16.07124 1.000 25.13392 ? 101 LYS A NZ  1 
ATOM   804  N N   . LEU A 1 103 ? -45.47147 12.77306 -8.91329  1.000 24.26965 ? 102 LEU A N   1 
ATOM   805  C CA  . LEU A 1 103 ? -44.67604 12.03969 -7.93291  1.000 26.83671 ? 102 LEU A CA  1 
ATOM   806  C C   . LEU A 1 103 ? -45.55792 11.38850 -6.86981  1.000 26.30760 ? 102 LEU A C   1 
ATOM   807  O O   . LEU A 1 103 ? -45.29198 10.25651 -6.44786  1.000 26.60882 ? 102 LEU A O   1 
ATOM   808  C CB  . LEU A 1 103 ? -43.64923 12.96339 -7.26513  1.000 22.32643 ? 102 LEU A CB  1 
ATOM   809  C CG  . LEU A 1 103 ? -42.46333 13.45113 -8.10929  1.000 28.47020 ? 102 LEU A CG  1 
ATOM   810  C CD1 . LEU A 1 103 ? -41.52796 14.32207 -7.29400  1.000 26.46884 ? 102 LEU A CD1 1 
ATOM   811  C CD2 . LEU A 1 103 ? -41.70189 12.28627 -8.74406  1.000 28.54509 ? 102 LEU A CD2 1 
ATOM   812  N N   . LEU A 1 104 ? -46.60211 12.08376 -6.40892  1.000 24.15226 ? 103 LEU A N   1 
ATOM   813  C CA  . LEU A 1 104 ? -47.38658 11.53588 -5.30762  1.000 28.52223 ? 103 LEU A CA  1 
ATOM   814  C C   . LEU A 1 104 ? -48.38663 10.47600 -5.74014  1.000 28.67384 ? 103 LEU A C   1 
ATOM   815  O O   . LEU A 1 104 ? -48.78126 9.65536  -4.90974  1.000 30.72670 ? 103 LEU A O   1 
ATOM   816  C CB  . LEU A 1 104 ? -48.14200 12.63736 -4.56506  1.000 27.62973 ? 103 LEU A CB  1 
ATOM   817  C CG  . LEU A 1 104 ? -47.29716 13.77434 -3.98598  1.000 30.39342 ? 103 LEU A CG  1 
ATOM   818  C CD1 . LEU A 1 104 ? -48.21042 14.84891 -3.38670  1.000 28.26355 ? 103 LEU A CD1 1 
ATOM   819  C CD2 . LEU A 1 104 ? -46.29886 13.25967 -2.96646  1.000 25.88100 ? 103 LEU A CD2 1 
ATOM   820  N N   . GLU A 1 105 ? -48.80138 10.47038 -7.00032  1.000 27.95294 ? 104 GLU A N   1 
ATOM   821  C CA  . GLU A 1 105 ? -49.91558 9.63618  -7.43769  1.000 31.89546 ? 104 GLU A CA  1 
ATOM   822  C C   . GLU A 1 105 ? -49.75088 8.14975  -7.10712  1.000 39.18352 ? 104 GLU A C   1 
ATOM   823  O O   . GLU A 1 105 ? -48.66753 7.58844  -7.26269  1.000 36.77146 ? 104 GLU A O   1 
ATOM   824  C CB  . GLU A 1 105 ? -50.11538 9.80671  -8.93070  1.000 29.87433 ? 104 GLU A CB  1 
ATOM   825  C CG  . GLU A 1 105 ? -51.24592 8.99319  -9.49863  1.000 36.80896 ? 104 GLU A CG  1 
ATOM   826  C CD  . GLU A 1 105 ? -50.72802 7.78351  -10.23510 1.000 42.81657 ? 104 GLU A CD  1 
ATOM   827  O OE1 . GLU A 1 105 ? -49.75557 7.95880  -10.99907 1.000 43.61030 ? 104 GLU A OE1 1 
ATOM   828  O OE2 . GLU A 1 105 ? -51.28759 6.67384  -10.05715 1.000 46.71315 ? 104 GLU A OE2 1 
ATOM   829  N N   . GLY B 1 1   ? -31.54939 23.22226 26.57419  1.000 50.23282 ? 0   GLY B N   1 
ATOM   830  C CA  . GLY B 1 1   ? -31.40955 24.26315 25.57102  1.000 49.87304 ? 0   GLY B CA  1 
ATOM   831  C C   . GLY B 1 1   ? -30.89671 23.73057 24.25490  1.000 54.41727 ? 0   GLY B C   1 
ATOM   832  O O   . GLY B 1 1   ? -31.14714 22.57588 23.90395  1.000 59.59178 ? 0   GLY B O   1 
ATOM   833  N N   . MET B 1 2   ? -30.17275 24.57399 23.52924  1.000 47.97422 ? 1   MET B N   1 
ATOM   834  C CA  . MET B 1 2   ? -29.67707 24.18887 22.21935  1.000 46.94540 ? 1   MET B CA  1 
ATOM   835  C C   . MET B 1 2   ? -28.60251 23.11279 22.35182  1.000 48.25883 ? 1   MET B C   1 
ATOM   836  O O   . MET B 1 2   ? -27.73837 23.17271 23.23334  1.000 42.52574 ? 1   MET B O   1 
ATOM   837  C CB  . MET B 1 2   ? -29.12258 25.41121 21.50235  1.000 49.98073 ? 1   MET B CB  1 
ATOM   838  C CG  . MET B 1 2   ? -28.65606 25.17821 20.09523  1.000 50.93073 ? 1   MET B CG  1 
ATOM   839  S SD  . MET B 1 2   ? -28.04104 26.73532 19.48285  1.000 67.54073 ? 1   MET B SD  1 
ATOM   840  C CE  . MET B 1 2   ? -29.52777 27.72110 19.54698  1.000 51.47073 ? 1   MET B CE  1 
ATOM   841  N N   . ILE B 1 3   ? -28.66539 22.12644 21.46523  1.000 40.22455 ? 2   ILE B N   1 
ATOM   842  C CA  . ILE B 1 3   ? -27.72215 21.01844 21.41974  1.000 40.87317 ? 2   ILE B CA  1 
ATOM   843  C C   . ILE B 1 3   ? -26.48639 21.43876 20.64022  1.000 40.29329 ? 2   ILE B C   1 
ATOM   844  O O   . ILE B 1 3   ? -26.59050 22.10435 19.60872  1.000 40.00082 ? 2   ILE B O   1 
ATOM   845  C CB  . ILE B 1 3   ? -28.39056 19.78342 20.78644  1.000 45.38748 ? 2   ILE B CB  1 
ATOM   846  C CG1 . ILE B 1 3   ? -29.16354 18.99768 21.85736  1.000 46.68686 ? 2   ILE B CG1 1 
ATOM   847  C CG2 . ILE B 1 3   ? -27.36970 18.91398 20.06222  1.000 40.97834 ? 2   ILE B CG2 1 
ATOM   848  C CD1 . ILE B 1 3   ? -30.48616 19.60486 22.20769  1.000 49.75454 ? 2   ILE B CD1 1 
ATOM   849  N N   . GLY B 1 4   ? -25.31018 21.03367 21.11972  1.000 35.83130 ? 3   GLY B N   1 
ATOM   850  C CA  . GLY B 1 4   ? -24.04708 21.32380 20.46069  1.000 38.14972 ? 3   GLY B CA  1 
ATOM   851  C C   . GLY B 1 4   ? -22.95865 21.69269 21.44772  1.000 38.77954 ? 3   GLY B C   1 
ATOM   852  O O   . GLY B 1 4   ? -23.25774 21.92292 22.61987  1.000 32.89412 ? 3   GLY B O   1 
ATOM   853  N N   . SER B 1 5   ? -21.70555 21.76533 20.99939  1.000 36.98386 ? 4   SER B N   1 
ATOM   854  C CA  . SER B 1 5   ? -20.64633 22.21845 21.88935  1.000 39.66507 ? 4   SER B CA  1 
ATOM   855  C C   . SER B 1 5   ? -20.91709 23.65034 22.35121  1.000 43.51972 ? 4   SER B C   1 
ATOM   856  O O   . SER B 1 5   ? -21.79461 24.35457 21.83505  1.000 37.84588 ? 4   SER B O   1 
ATOM   857  C CB  . SER B 1 5   ? -19.27817 22.13173 21.20204  1.000 37.32045 ? 4   SER B CB  1 
ATOM   858  O OG  . SER B 1 5   ? -19.12133 23.16626 20.24157  1.000 40.76760 ? 4   SER B OG  1 
ATOM   859  N N   . GLU B 1 6   ? -20.14170 24.08560 23.34673  1.000 42.73895 ? 5   GLU B N   1 
ATOM   860  C CA  . GLU B 1 6   ? -20.24912 25.46887 23.80107  1.000 42.03501 ? 5   GLU B CA  1 
ATOM   861  C C   . GLU B 1 6   ? -19.88103 26.43452 22.67816  1.000 39.04853 ? 5   GLU B C   1 
ATOM   862  O O   . GLU B 1 6   ? -20.49687 27.49708 22.53239  1.000 37.83063 ? 5   GLU B O   1 
ATOM   863  C CB  . GLU B 1 6   ? -19.36999 25.69428 25.04236  1.000 45.82786 ? 5   GLU B CB  1 
ATOM   864  C CG  . GLU B 1 6   ? -19.45391 27.11449 25.62277  1.000 53.49702 ? 5   GLU B CG  1 
ATOM   865  C CD  . GLU B 1 6   ? -18.16372 27.56101 26.34276  1.000 63.56916 ? 5   GLU B CD  1 
ATOM   866  O OE1 . GLU B 1 6   ? -17.28624 26.70432 26.62434  1.000 66.22599 ? 5   GLU B OE1 1 
ATOM   867  O OE2 . GLU B 1 6   ? -18.02559 28.77554 26.62087  1.000 56.95335 ? 5   GLU B OE2 1 
ATOM   868  N N   . LYS B 1 7   ? -18.89136 26.06299 21.86113  1.000 33.35374 ? 6   LYS B N   1 
ATOM   869  C CA  . LYS B 1 7   ? -18.51441 26.90203 20.73357  1.000 39.68320 ? 6   LYS B CA  1 
ATOM   870  C C   . LYS B 1 7   ? -19.64341 26.97277 19.71300  1.000 40.63133 ? 6   LYS B C   1 
ATOM   871  O O   . LYS B 1 7   ? -19.98945 28.06401 19.24211  1.000 36.73314 ? 6   LYS B O   1 
ATOM   872  C CB  . LYS B 1 7   ? -17.22927 26.37416 20.09295  1.000 38.78194 ? 6   LYS B CB  1 
ATOM   873  C CG  . LYS B 1 7   ? -16.88365 27.06299 18.78188  1.000 46.22442 ? 6   LYS B CG  1 
ATOM   874  C CD  . LYS B 1 7   ? -15.76792 26.33912 18.02456  1.000 49.09515 ? 6   LYS B CD  1 
ATOM   875  C CE  . LYS B 1 7   ? -16.06974 26.25442 16.52162  1.000 58.00211 ? 6   LYS B CE  1 
ATOM   876  N NZ  . LYS B 1 7   ? -17.48260 25.80595 16.23165  1.000 53.60680 ? 6   LYS B NZ  1 
ATOM   877  N N   . GLN B 1 8   ? -20.23706 25.82186 19.37025  1.000 38.87990 ? 7   GLN B N   1 
ATOM   878  C CA  . GLN B 1 8   ? -21.32793 25.79950 18.39754  1.000 38.60592 ? 7   GLN B CA  1 
ATOM   879  C C   . GLN B 1 8   ? -22.54858 26.54740 18.91323  1.000 34.07517 ? 7   GLN B C   1 
ATOM   880  O O   . GLN B 1 8   ? -23.19834 27.27812 18.15555  1.000 34.18232 ? 7   GLN B O   1 
ATOM   881  C CB  . GLN B 1 8   ? -21.69855 24.35916 18.04417  1.000 34.54722 ? 7   GLN B CB  1 
ATOM   882  C CG  . GLN B 1 8   ? -20.57680 23.57508 17.38146  1.000 35.49076 ? 7   GLN B CG  1 
ATOM   883  C CD  . GLN B 1 8   ? -20.89531 22.09799 17.24724  1.000 40.32030 ? 7   GLN B CD  1 
ATOM   884  O OE1 . GLN B 1 8   ? -21.46573 21.48449 18.15885  1.000 45.34148 ? 7   GLN B OE1 1 
ATOM   885  N NE2 . GLN B 1 8   ? -20.52980 21.51648 16.10822  1.000 38.43370 ? 7   GLN B NE2 1 
ATOM   886  N N   . VAL B 1 9   ? -22.88485 26.37575 20.19206  1.000 33.07376 ? 8   VAL B N   1 
ATOM   887  C CA  . VAL B 1 9   ? -24.04179 27.07649 20.73660  1.000 35.88086 ? 8   VAL B CA  1 
ATOM   888  C C   . VAL B 1 9   ? -23.80718 28.58545 20.70737  1.000 41.39042 ? 8   VAL B C   1 
ATOM   889  O O   . VAL B 1 9   ? -24.70333 29.36443 20.34643  1.000 37.27691 ? 8   VAL B O   1 
ATOM   890  C CB  . VAL B 1 9   ? -24.36347 26.56815 22.15292  1.000 35.68507 ? 8   VAL B CB  1 
ATOM   891  C CG1 . VAL B 1 9   ? -25.32337 27.51007 22.84256  1.000 34.90425 ? 8   VAL B CG1 1 
ATOM   892  C CG2 . VAL B 1 9   ? -24.95564 25.16579 22.08876  1.000 38.32404 ? 8   VAL B CG2 1 
ATOM   893  N N   . ASN B 1 10  ? -22.59300 29.02082 21.06313  1.000 35.72734 ? 9   ASN B N   1 
ATOM   894  C CA  . ASN B 1 10  ? -22.27981 30.44457 21.00715  1.000 36.87921 ? 9   ASN B CA  1 
ATOM   895  C C   . ASN B 1 10  ? -22.40539 30.96806 19.58186  1.000 37.38136 ? 9   ASN B C   1 
ATOM   896  O O   . ASN B 1 10  ? -22.99245 32.03363 19.34322  1.000 36.75058 ? 9   ASN B O   1 
ATOM   897  C CB  . ASN B 1 10  ? -20.86815 30.69129 21.55034  1.000 35.47460 ? 9   ASN B CB  1 
ATOM   898  C CG  . ASN B 1 10  ? -20.85188 30.95754 23.04859  1.000 37.05095 ? 9   ASN B CG  1 
ATOM   899  O OD1 . ASN B 1 10  ? -21.89844 31.13414 23.67012  1.000 33.12741 ? 9   ASN B OD1 1 
ATOM   900  N ND2 . ASN B 1 10  ? -19.65431 30.96351 23.63958  1.000 37.81143 ? 9   ASN B ND2 1 
ATOM   901  N N   . TRP B 1 11  ? -21.86638 30.22543 18.62037  1.000 31.74549 ? 10  TRP B N   1 
ATOM   902  C CA  . TRP B 1 11  ? -21.92769 30.65649 17.23091  1.000 35.17563 ? 10  TRP B CA  1 
ATOM   903  C C   . TRP B 1 11  ? -23.36678 30.66098 16.72033  1.000 35.91768 ? 10  TRP B C   1 
ATOM   904  O O   . TRP B 1 11  ? -23.81775 31.64128 16.11338  1.000 35.00426 ? 10  TRP B O   1 
ATOM   905  C CB  . TRP B 1 11  ? -21.04515 29.75013 16.37916  1.000 32.79704 ? 10  TRP B CB  1 
ATOM   906  C CG  . TRP B 1 11  ? -20.87308 30.22565 14.98208  1.000 33.48600 ? 10  TRP B CG  1 
ATOM   907  C CD1 . TRP B 1 11  ? -21.29791 31.41407 14.45578  1.000 32.94105 ? 10  TRP B CD1 1 
ATOM   908  C CD2 . TRP B 1 11  ? -20.20251 29.53207 13.92633  1.000 31.66494 ? 10  TRP B CD2 1 
ATOM   909  N NE1 . TRP B 1 11  ? -20.94040 31.49537 13.12508  1.000 31.67027 ? 10  TRP B NE1 1 
ATOM   910  C CE2 . TRP B 1 11  ? -20.26473 30.35369 12.77929  1.000 31.24937 ? 10  TRP B CE2 1 
ATOM   911  C CE3 . TRP B 1 11  ? -19.55520 28.29296 13.83820  1.000 35.25274 ? 10  TRP B CE3 1 
ATOM   912  C CZ2 . TRP B 1 11  ? -19.71019 29.97460 11.56143  1.000 33.75642 ? 10  TRP B CZ2 1 
ATOM   913  C CZ3 . TRP B 1 11  ? -18.99708 27.91821 12.62463  1.000 33.48307 ? 10  TRP B CZ3 1 
ATOM   914  C CH2 . TRP B 1 11  ? -19.08170 28.75659 11.50250  1.000 33.41621 ? 10  TRP B CH2 1 
ATOM   915  N N   . ALA B 1 12  ? -24.10851 29.57851 16.97668  1.000 34.78131 ? 11  ALA B N   1 
ATOM   916  C CA  . ALA B 1 12  ? -25.48672 29.49602 16.50796  1.000 36.64645 ? 11  ALA B CA  1 
ATOM   917  C C   . ALA B 1 12  ? -26.33873 30.61232 17.09615  1.000 37.09196 ? 11  ALA B C   1 
ATOM   918  O O   . ALA B 1 12  ? -27.15054 31.22014 16.38655  1.000 34.10613 ? 11  ALA B O   1 
ATOM   919  C CB  . ALA B 1 12  ? -26.07691 28.12920 16.85170  1.000 33.03433 ? 11  ALA B CB  1 
ATOM   920  N N   . LYS B 1 13  ? -26.16306 30.90787 18.38870  1.000 33.01789 ? 12  LYS B N   1 
ATOM   921  C CA  . LYS B 1 13  ? -26.97498 31.94975 19.00803  1.000 32.89605 ? 12  LYS B CA  1 
ATOM   922  C C   . LYS B 1 13  ? -26.69526 33.30595 18.37078  1.000 37.34132 ? 12  LYS B C   1 
ATOM   923  O O   . LYS B 1 13  ? -27.61790 34.10554 18.16160  1.000 35.42720 ? 12  LYS B O   1 
ATOM   924  C CB  . LYS B 1 13  ? -26.73878 31.99639 20.52282  1.000 36.25811 ? 12  LYS B CB  1 
ATOM   925  C CG  . LYS B 1 13  ? -27.61976 31.02344 21.33355  1.000 40.38031 ? 12  LYS B CG  1 
ATOM   926  C CD  . LYS B 1 13  ? -26.94361 30.58984 22.63542  1.000 46.14221 ? 12  LYS B CD  1 
ATOM   927  C CE  . LYS B 1 13  ? -27.93814 30.36740 23.79281  1.000 50.92315 ? 12  LYS B CE  1 
ATOM   928  N NZ  . LYS B 1 13  ? -27.24098 30.00703 25.09555  1.000 55.67597 ? 12  LYS B NZ  1 
ATOM   929  N N   . SER B 1 14  ? -25.43252 33.57649 18.03113  1.000 31.85781 ? 13  SER B N   1 
ATOM   930  C CA  . SER B 1 14  ? -25.12632 34.84510 17.37949  1.000 37.06909 ? 13  SER B CA  1 
ATOM   931  C C   . SER B 1 14  ? -25.69481 34.89600 15.96160  1.000 36.24659 ? 13  SER B C   1 
ATOM   932  O O   . SER B 1 14  ? -26.11105 35.96694 15.50428  1.000 35.83972 ? 13  SER B O   1 
ATOM   933  C CB  . SER B 1 14  ? -23.61412 35.09539 17.39369  1.000 32.08004 ? 13  SER B CB  1 
ATOM   934  O OG  . SER B 1 14  ? -22.97355 34.57849 16.23556  1.000 34.23339 ? 13  SER B OG  1 
ATOM   935  N N   . ILE B 1 15  ? -25.74343 33.75672 15.26502  1.000 31.74827 ? 14  ILE B N   1 
ATOM   936  C CA  . ILE B 1 15  ? -26.39798 33.70907 13.95796  1.000 35.23716 ? 14  ILE B CA  1 
ATOM   937  C C   . ILE B 1 15  ? -27.88238 34.04417 14.09164  1.000 33.57245 ? 14  ILE B C   1 
ATOM   938  O O   . ILE B 1 15  ? -28.41399 34.89791 13.37082  1.000 33.82455 ? 14  ILE B O   1 
ATOM   939  C CB  . ILE B 1 15  ? -26.18952 32.33144 13.30344  1.000 34.34493 ? 14  ILE B CB  1 
ATOM   940  C CG1 . ILE B 1 15  ? -24.72823 32.15908 12.89088  1.000 32.48960 ? 14  ILE B CG1 1 
ATOM   941  C CG2 . ILE B 1 15  ? -27.12016 32.16450 12.10239  1.000 29.12755 ? 14  ILE B CG2 1 
ATOM   942  C CD1 . ILE B 1 15  ? -24.30813 30.72256 12.72129  1.000 31.87794 ? 14  ILE B CD1 1 
ATOM   943  N N   . ILE B 1 16  ? -28.56920 33.38223 15.02533  1.000 31.05015 ? 15  ILE B N   1 
ATOM   944  C CA  . ILE B 1 16  ? -30.00959 33.57689 15.17352  1.000 32.19872 ? 15  ILE B CA  1 
ATOM   945  C C   . ILE B 1 16  ? -30.32477 35.02074 15.54690  1.000 37.74776 ? 15  ILE B C   1 
ATOM   946  O O   . ILE B 1 16  ? -31.23267 35.64409 14.97637  1.000 35.21458 ? 15  ILE B O   1 
ATOM   947  C CB  . ILE B 1 16  ? -30.57342 32.58680 16.20926  1.000 31.16263 ? 15  ILE B CB  1 
ATOM   948  C CG1 . ILE B 1 16  ? -30.41949 31.14813 15.69679  1.000 32.81303 ? 15  ILE B CG1 1 
ATOM   949  C CG2 . ILE B 1 16  ? -32.01496 32.95635 16.59199  1.000 30.59908 ? 15  ILE B CG2 1 
ATOM   950  C CD1 . ILE B 1 16  ? -31.40713 30.76363 14.61945  1.000 29.00891 ? 15  ILE B CD1 1 
ATOM   951  N N   . GLU B 1 17  ? -29.57333 35.58070 16.49864  1.000 34.46229 ? 16  GLU B N   1 
ATOM   952  C CA  . GLU B 1 17  ? -29.81813 36.95663 16.92216  1.000 35.94002 ? 16  GLU B CA  1 
ATOM   953  C C   . GLU B 1 17  ? -29.55906 37.94069 15.79091  1.000 32.19079 ? 16  GLU B C   1 
ATOM   954  O O   . GLU B 1 17  ? -30.25963 38.94815 15.66466  1.000 33.15547 ? 16  GLU B O   1 
ATOM   955  C CB  . GLU B 1 17  ? -28.94959 37.28863 18.13832  1.000 37.15078 ? 16  GLU B CB  1 
ATOM   956  C CG  . GLU B 1 17  ? -29.52140 36.78572 19.46520  1.000 34.13173 ? 16  GLU B CG  1 
ATOM   957  C CD  . GLU B 1 17  ? -31.01319 37.05818 19.61244  1.000 41.43777 ? 16  GLU B CD  1 
ATOM   958  O OE1 . GLU B 1 17  ? -31.39453 38.25229 19.69744  1.000 42.53910 ? 16  GLU B OE1 1 
ATOM   959  O OE2 . GLU B 1 17  ? -31.80236 36.08640 19.68237  1.000 39.75285 ? 16  GLU B OE2 1 
ATOM   960  N N   . LYS B 1 18  ? -28.56246 37.66366 14.95312  1.000 31.47989 ? 17  LYS B N   1 
ATOM   961  C CA  . LYS B 1 18  ? -28.31555 38.52169 13.79801  1.000 36.36460 ? 17  LYS B CA  1 
ATOM   962  C C   . LYS B 1 18  ? -29.49047 38.47248 12.81710  1.000 36.27605 ? 17  LYS B C   1 
ATOM   963  O O   . LYS B 1 18  ? -29.92780 39.51115 12.29875  1.000 35.50484 ? 17  LYS B O   1 
ATOM   964  C CB  . LYS B 1 18  ? -27.00101 38.10131 13.14159  1.000 33.42644 ? 17  LYS B CB  1 
ATOM   965  C CG  . LYS B 1 18  ? -26.74539 38.60999 11.73260  1.000 35.05025 ? 17  LYS B CG  1 
ATOM   966  C CD  . LYS B 1 18  ? -25.65117 37.76190 11.08850  1.000 37.47363 ? 17  LYS B CD  1 
ATOM   967  C CE  . LYS B 1 18  ? -25.47750 38.09284 9.61811   1.000 44.43317 ? 17  LYS B CE  1 
ATOM   968  N NZ  . LYS B 1 18  ? -24.05162 38.00933 9.20857   1.000 48.98650 ? 17  LYS B NZ  1 
ATOM   969  N N   . GLU B 1 19  ? -30.04204 37.28164 12.58882  1.000 32.37452 ? 18  GLU B N   1 
ATOM   970  C CA  . GLU B 1 19  ? -31.20252 37.15596 11.71222  1.000 32.93880 ? 18  GLU B CA  1 
ATOM   971  C C   . GLU B 1 19  ? -32.43001 37.82038 12.32998  1.000 33.37693 ? 18  GLU B C   1 
ATOM   972  O O   . GLU B 1 19  ? -33.14325 38.57351 11.65556  1.000 33.72536 ? 18  GLU B O   1 
ATOM   973  C CB  . GLU B 1 19  ? -31.47684 35.68024 11.42027  1.000 24.84503 ? 18  GLU B CB  1 
ATOM   974  C CG  . GLU B 1 19  ? -30.45835 35.00444 10.51198  1.000 28.55764 ? 18  GLU B CG  1 
ATOM   975  C CD  . GLU B 1 19  ? -30.10570 35.82541 9.28164   1.000 32.78763 ? 18  GLU B CD  1 
ATOM   976  O OE1 . GLU B 1 19  ? -31.04849 36.30635 8.60896   1.000 32.94577 ? 18  GLU B OE1 1 
ATOM   977  O OE2 . GLU B 1 19  ? -28.89608 35.96922 8.97084   1.000 29.71625 ? 18  GLU B OE2 1 
ATOM   978  N N   . VAL B 1 20  ? -32.70347 37.54362 13.61070  1.000 32.22505 ? 19  VAL B N   1 
ATOM   979  C CA  . VAL B 1 20  ? -33.83700 38.18403 14.27347  1.000 31.52915 ? 19  VAL B CA  1 
ATOM   980  C C   . VAL B 1 20  ? -33.73045 39.70176 14.16925  1.000 35.22521 ? 19  VAL B C   1 
ATOM   981  O O   . VAL B 1 20  ? -34.73017 40.39112 13.92549  1.000 35.04583 ? 19  VAL B O   1 
ATOM   982  C CB  . VAL B 1 20  ? -33.94558 37.72290 15.73873  1.000 34.28958 ? 19  VAL B CB  1 
ATOM   983  C CG1 . VAL B 1 20  ? -34.99524 38.54447 16.47421  1.000 31.33048 ? 19  VAL B CG1 1 
ATOM   984  C CG2 . VAL B 1 20  ? -34.30583 36.24726 15.80525  1.000 29.91624 ? 19  VAL B CG2 1 
ATOM   985  N N   . GLU B 1 21  ? -32.51709 40.24468 14.33271  1.000 32.35341 ? 20  GLU B N   1 
ATOM   986  C CA  . GLU B 1 21  ? -32.32114 41.68402 14.16977  1.000 35.61522 ? 20  GLU B CA  1 
ATOM   987  C C   . GLU B 1 21  ? -32.65389 42.13719 12.75054  1.000 32.04940 ? 20  GLU B C   1 
ATOM   988  O O   . GLU B 1 21  ? -33.26401 43.19505 12.56112  1.000 34.26731 ? 20  GLU B O   1 
ATOM   989  C CB  . GLU B 1 21  ? -30.88374 42.06950 14.52764  1.000 38.31516 ? 20  GLU B CB  1 
ATOM   990  C CG  . GLU B 1 21  ? -30.43887 43.44418 14.01353  1.000 43.33381 ? 20  GLU B CG  1 
ATOM   991  C CD  . GLU B 1 21  ? -29.01364 43.81159 14.44248  1.000 53.95983 ? 20  GLU B CD  1 
ATOM   992  O OE1 . GLU B 1 21  ? -28.05731 43.49285 13.68827  1.000 51.61689 ? 20  GLU B OE1 1 
ATOM   993  O OE2 . GLU B 1 21  ? -28.85391 44.43434 15.52339  1.000 53.82342 ? 20  GLU B OE2 1 
ATOM   994  N N   . ALA B 1 22  ? -32.24813 41.36167 11.74005  1.000 28.58851 ? 21  ALA B N   1 
ATOM   995  C CA  . ALA B 1 22  ? -32.55471 41.73082 10.36232  1.000 33.71704 ? 21  ALA B CA  1 
ATOM   996  C C   . ALA B 1 22  ? -34.06213 41.75852 10.13118  1.000 31.75702 ? 21  ALA B C   1 
ATOM   997  O O   . ALA B 1 22  ? -34.59595 42.71317 9.55269   1.000 31.26720 ? 21  ALA B O   1 
ATOM   998  C CB  . ALA B 1 22  ? -31.87133 40.76904 9.38754   1.000 32.74204 ? 21  ALA B CB  1 
ATOM   999  N N   . TRP B 1 23  ? -34.76812 40.72628 10.60295  1.000 31.19023 ? 22  TRP B N   1 
ATOM   1000 C CA  . TRP B 1 23  ? -36.22084 40.68717 10.45387  1.000 31.54842 ? 22  TRP B CA  1 
ATOM   1001 C C   . TRP B 1 23  ? -36.88111 41.81881 11.23011  1.000 32.55502 ? 22  TRP B C   1 
ATOM   1002 O O   . TRP B 1 23  ? -37.86919 42.40745 10.77339  1.000 33.29590 ? 22  TRP B O   1 
ATOM   1003 C CB  . TRP B 1 23  ? -36.76642 39.32389 10.91064  1.000 26.17477 ? 22  TRP B CB  1 
ATOM   1004 C CG  . TRP B 1 23  ? -36.51529 38.20294 9.90383   1.000 29.62815 ? 22  TRP B CG  1 
ATOM   1005 C CD1 . TRP B 1 23  ? -35.38505 37.44092 9.77918   1.000 27.69414 ? 22  TRP B CD1 1 
ATOM   1006 C CD2 . TRP B 1 23  ? -37.41537 37.74969 8.87407   1.000 31.10354 ? 22  TRP B CD2 1 
ATOM   1007 N NE1 . TRP B 1 23  ? -35.52612 36.54083 8.74090   1.000 27.31606 ? 22  TRP B NE1 1 
ATOM   1008 C CE2 . TRP B 1 23  ? -36.76258 36.71114 8.17327   1.000 29.32096 ? 22  TRP B CE2 1 
ATOM   1009 C CE3 . TRP B 1 23  ? -38.71015 38.12148 8.48178   1.000 29.76220 ? 22  TRP B CE3 1 
ATOM   1010 C CZ2 . TRP B 1 23  ? -37.36588 36.03584 7.10497   1.000 30.63422 ? 22  TRP B CZ2 1 
ATOM   1011 C CZ3 . TRP B 1 23  ? -39.30373 37.44997 7.41737   1.000 27.26266 ? 22  TRP B CZ3 1 
ATOM   1012 C CH2 . TRP B 1 23  ? -38.63125 36.42271 6.74266   1.000 26.12915 ? 22  TRP B CH2 1 
ATOM   1013 N N   . GLU B 1 24  ? -36.35049 42.14746 12.40140  1.000 30.97074 ? 23  GLU B N   1 
ATOM   1014 C CA  . GLU B 1 24  ? -36.98312 43.18426 13.20311  1.000 32.23756 ? 23  GLU B CA  1 
ATOM   1015 C C   . GLU B 1 24  ? -36.71236 44.57932 12.65864  1.000 32.68742 ? 23  GLU B C   1 
ATOM   1016 O O   . GLU B 1 24  ? -37.45930 45.50799 12.97617  1.000 34.54524 ? 23  GLU B O   1 
ATOM   1017 C CB  . GLU B 1 24  ? -36.52491 43.06941 14.65768  1.000 32.57914 ? 23  GLU B CB  1 
ATOM   1018 C CG  . GLU B 1 24  ? -37.18592 41.89971 15.36480  1.000 33.58029 ? 23  GLU B CG  1 
ATOM   1019 C CD  . GLU B 1 24  ? -36.78133 41.76023 16.82194  1.000 38.15206 ? 23  GLU B CD  1 
ATOM   1020 O OE1 . GLU B 1 24  ? -35.84645 42.46581 17.27032  1.000 37.21109 ? 23  GLU B OE1 1 
ATOM   1021 O OE2 . GLU B 1 24  ? -37.41243 40.93211 17.51421  1.000 35.81367 ? 23  GLU B OE2 1 
ATOM   1022 N N   . ALA B 1 25  ? -35.68437 44.74275 11.82350  1.000 30.54011 ? 24  ALA B N   1 
ATOM   1023 C CA  . ALA B 1 25  ? -35.43164 46.03655 11.21596  1.000 29.45814 ? 24  ALA B CA  1 
ATOM   1024 C C   . ALA B 1 25  ? -36.41949 46.36750 10.09968  1.000 31.29349 ? 24  ALA B C   1 
ATOM   1025 O O   . ALA B 1 25  ? -36.42210 47.50687 9.62242   1.000 31.32034 ? 24  ALA B O   1 
ATOM   1026 C CB  . ALA B 1 25  ? -33.99899 46.08393 10.68104  1.000 30.40453 ? 24  ALA B CB  1 
ATOM   1027 N N   . ILE B 1 26  ? -37.25297 45.41304 9.67120   1.000 30.64352 ? 25  ILE B N   1 
ATOM   1028 C CA  . ILE B 1 26  ? -38.21694 45.68975 8.60299   1.000 31.37222 ? 25  ILE B CA  1 
ATOM   1029 C C   . ILE B 1 26  ? -39.19724 46.77786 9.03642   1.000 30.69101 ? 25  ILE B C   1 
ATOM   1030 O O   . ILE B 1 26  ? -39.49710 47.71150 8.28017   1.000 30.71500 ? 25  ILE B O   1 
ATOM   1031 C CB  . ILE B 1 26  ? -38.95449 44.40048 8.19489   1.000 30.24620 ? 25  ILE B CB  1 
ATOM   1032 C CG1 . ILE B 1 26  ? -37.98314 43.38001 7.59328   1.000 32.88892 ? 25  ILE B CG1 1 
ATOM   1033 C CG2 . ILE B 1 26  ? -40.06219 44.71058 7.19806   1.000 33.57261 ? 25  ILE B CG2 1 
ATOM   1034 C CD1 . ILE B 1 26  ? -38.61233 42.01356 7.34199   1.000 29.03460 ? 25  ILE B CD1 1 
ATOM   1035 N N   . GLY B 1 27  ? -39.71103 46.67323 10.25833  1.000 33.52375 ? 26  GLY B N   1 
ATOM   1036 C CA  . GLY B 1 27  ? -40.65497 47.64248 10.78239  1.000 31.29784 ? 26  GLY B CA  1 
ATOM   1037 C C   . GLY B 1 27  ? -42.10412 47.20592 10.78843  1.000 31.53047 ? 26  GLY B C   1 
ATOM   1038 O O   . GLY B 1 27  ? -42.98522 48.04982 10.99599  1.000 29.25694 ? 26  GLY B O   1 
ATOM   1039 N N   . VAL B 1 28  ? -42.38262 45.92918 10.53708  1.000 28.19848 ? 27  VAL B N   1 
ATOM   1040 C CA  . VAL B 1 28  ? -43.71611 45.36610 10.68922  1.000 27.38868 ? 27  VAL B CA  1 
ATOM   1041 C C   . VAL B 1 28  ? -43.59469 44.16924 11.62009  1.000 31.27859 ? 27  VAL B C   1 
ATOM   1042 O O   . VAL B 1 28  ? -42.49661 43.67523 11.88368  1.000 32.25858 ? 27  VAL B O   1 
ATOM   1043 C CB  . VAL B 1 28  ? -44.34483 44.95335 9.34378   1.000 29.01855 ? 27  VAL B CB  1 
ATOM   1044 C CG1 . VAL B 1 28  ? -44.31979 46.10535 8.37061   1.000 26.73756 ? 27  VAL B CG1 1 
ATOM   1045 C CG2 . VAL B 1 28  ? -43.61778 43.75299 8.76383   1.000 28.98383 ? 27  VAL B CG2 1 
ATOM   1046 N N   . ASP B 1 29  ? -44.74240 43.70577 12.12001  1.000 28.91428 ? 28  ASP B N   1 
ATOM   1047 C CA  . ASP B 1 29  ? -44.75231 42.62911 13.09907  1.000 30.59496 ? 28  ASP B CA  1 
ATOM   1048 C C   . ASP B 1 29  ? -44.13402 41.36938 12.49580  1.000 32.44499 ? 28  ASP B C   1 
ATOM   1049 O O   . ASP B 1 29  ? -44.60585 40.86948 11.46993  1.000 34.33300 ? 28  ASP B O   1 
ATOM   1050 C CB  . ASP B 1 29  ? -46.18775 42.37242 13.55244  1.000 29.96892 ? 28  ASP B CB  1 
ATOM   1051 C CG  . ASP B 1 29  ? -46.29346 41.26409 14.59467  1.000 36.39199 ? 28  ASP B CG  1 
ATOM   1052 O OD1 . ASP B 1 29  ? -45.25909 40.83776 15.14611  1.000 36.98346 ? 28  ASP B OD1 1 
ATOM   1053 O OD2 . ASP B 1 29  ? -47.42362 40.80908 14.86165  1.000 42.32746 ? 28  ASP B OD2 1 
ATOM   1054 N N   . VAL B 1 30  ? -43.05913 40.87362 13.11064  1.000 28.00984 ? 29  VAL B N   1 
ATOM   1055 C CA  . VAL B 1 30  ? -42.40192 39.65338 12.63973  1.000 29.37693 ? 29  VAL B CA  1 
ATOM   1056 C C   . VAL B 1 30  ? -42.21855 38.69480 13.80489  1.000 31.46232 ? 29  VAL B C   1 
ATOM   1057 O O   . VAL B 1 30  ? -41.42238 37.75243 13.72467  1.000 30.62122 ? 29  VAL B O   1 
ATOM   1058 C CB  . VAL B 1 30  ? -41.04285 39.95237 11.97120  1.000 29.39648 ? 29  VAL B CB  1 
ATOM   1059 C CG1 . VAL B 1 30  ? -41.23132 40.83691 10.72043  1.000 26.21055 ? 29  VAL B CG1 1 
ATOM   1060 C CG2 . VAL B 1 30  ? -40.05641 40.58187 12.97777  1.000 26.52276 ? 29  VAL B CG2 1 
ATOM   1061 N N   . ARG B 1 31  ? -42.95724 38.93046 14.89317  1.000 33.82413 ? 30  ARG B N   1 
ATOM   1062 C CA  . ARG B 1 31  ? -42.75968 38.16467 16.12651  1.000 36.53081 ? 30  ARG B CA  1 
ATOM   1063 C C   . ARG B 1 31  ? -42.82093 36.65925 15.88379  1.000 34.84259 ? 30  ARG B C   1 
ATOM   1064 O O   . ARG B 1 31  ? -42.03501 35.89859 16.46461  1.000 34.70740 ? 30  ARG B O   1 
ATOM   1065 C CB  . ARG B 1 31  ? -43.80458 38.58024 17.16739  1.000 34.90747 ? 30  ARG B CB  1 
ATOM   1066 C CG  . ARG B 1 31  ? -43.34886 39.73266 18.05706  1.000 40.85556 ? 30  ARG B CG  1 
ATOM   1067 C CD  . ARG B 1 31  ? -44.49961 40.32089 18.87356  1.000 42.13663 ? 30  ARG B CD  1 
ATOM   1068 N NE  . ARG B 1 31  ? -45.67285 40.56116 18.04579  1.000 43.83542 ? 30  ARG B NE  1 
ATOM   1069 C CZ  . ARG B 1 31  ? -46.89541 40.12981 18.32772  1.000 50.50851 ? 30  ARG B CZ  1 
ATOM   1070 N NH1 . ARG B 1 31  ? -47.15061 39.45242 19.43511  1.000 50.07445 ? 30  ARG B NH1 1 
ATOM   1071 N NH2 . ARG B 1 31  ? -47.88672 40.38343 17.47496  1.000 43.90830 ? 30  ARG B NH2 1 
ATOM   1072 N N   . GLU B 1 32  ? -43.74224 36.21088 15.02237  1.000 31.45451 ? 31  GLU B N   1 
ATOM   1073 C CA  . GLU B 1 32  ? -43.87030 34.77885 14.74860  1.000 31.14038 ? 31  GLU B CA  1 
ATOM   1074 C C   . GLU B 1 32  ? -42.60395 34.21618 14.11965  1.000 28.61194 ? 31  GLU B C   1 
ATOM   1075 O O   . GLU B 1 32  ? -42.19106 33.09436 14.43715  1.000 31.62870 ? 31  GLU B O   1 
ATOM   1076 C CB  . GLU B 1 32  ? -45.06897 34.50966 13.83436  1.000 29.47036 ? 31  GLU B CB  1 
ATOM   1077 C CG  . GLU B 1 32  ? -45.43341 33.04217 13.76078  1.000 33.55648 ? 31  GLU B CG  1 
ATOM   1078 C CD  . GLU B 1 32  ? -46.60314 32.75474 12.83767  1.000 36.10713 ? 31  GLU B CD  1 
ATOM   1079 O OE1 . GLU B 1 32  ? -47.35529 33.69691 12.49867  1.000 34.64487 ? 31  GLU B OE1 1 
ATOM   1080 O OE2 . GLU B 1 32  ? -46.77550 31.57307 12.45494  1.000 34.61004 ? 31  GLU B OE2 1 
ATOM   1081 N N   . VAL B 1 33  ? -41.97920 34.97253 13.21324  1.000 26.86087 ? 32  VAL B N   1 
ATOM   1082 C CA  . VAL B 1 33  ? -40.73115 34.51180 12.60760  1.000 28.07236 ? 32  VAL B CA  1 
ATOM   1083 C C   . VAL B 1 33  ? -39.58993 34.56427 13.62267  1.000 31.25652 ? 32  VAL B C   1 
ATOM   1084 O O   . VAL B 1 33  ? -38.72577 33.67619 13.65539  1.000 27.09617 ? 32  VAL B O   1 
ATOM   1085 C CB  . VAL B 1 33  ? -40.39800 35.33973 11.35443  1.000 28.96689 ? 32  VAL B CB  1 
ATOM   1086 C CG1 . VAL B 1 33  ? -38.96452 35.05169 10.89789  1.000 26.34103 ? 32  VAL B CG1 1 
ATOM   1087 C CG2 . VAL B 1 33  ? -41.40858 35.06693 10.22403  1.000 24.80909 ? 32  VAL B CG2 1 
ATOM   1088 N N   . ALA B 1 34  ? -39.55456 35.60977 14.45630  1.000 28.97521 ? 33  ALA B N   1 
ATOM   1089 C CA  . ALA B 1 34  ? -38.49064 35.70640 15.44981  1.000 30.16882 ? 33  ALA B CA  1 
ATOM   1090 C C   . ALA B 1 34  ? -38.59461 34.57373 16.45878  1.000 29.08154 ? 33  ALA B C   1 
ATOM   1091 O O   . ALA B 1 34  ? -37.58229 33.99062 16.85281  1.000 31.87682 ? 33  ALA B O   1 
ATOM   1092 C CB  . ALA B 1 34  ? -38.53695 37.06194 16.15421  1.000 30.56640 ? 33  ALA B CB  1 
ATOM   1093 N N   . ALA B 1 35  ? -39.81565 34.23466 16.87389  1.000 31.23359 ? 34  ALA B N   1 
ATOM   1094 C CA  . ALA B 1 35  ? -39.99314 33.12582 17.80293  1.000 32.27686 ? 34  ALA B CA  1 
ATOM   1095 C C   . ALA B 1 35  ? -39.58973 31.80403 17.16503  1.000 32.59469 ? 34  ALA B C   1 
ATOM   1096 O O   . ALA B 1 35  ? -38.98216 30.95402 17.82651  1.000 29.18123 ? 34  ALA B O   1 
ATOM   1097 C CB  . ALA B 1 35  ? -41.44153 33.06923 18.28742  1.000 31.79515 ? 34  ALA B CB  1 
ATOM   1098 N N   . PHE B 1 36  ? -39.92585 31.60908 15.88071  1.000 29.01281 ? 35  PHE B N   1 
ATOM   1099 C CA  . PHE B 1 36  ? -39.52323 30.38466 15.18713  1.000 28.88230 ? 35  PHE B CA  1 
ATOM   1100 C C   . PHE B 1 36  ? -38.00971 30.25572 15.14796  1.000 29.39202 ? 35  PHE B C   1 
ATOM   1101 O O   . PHE B 1 36  ? -37.45533 29.19419 15.46676  1.000 31.81187 ? 35  PHE B O   1 
ATOM   1102 C CB  . PHE B 1 36  ? -40.08276 30.35274 13.75881  1.000 29.44099 ? 35  PHE B CB  1 
ATOM   1103 C CG  . PHE B 1 36  ? -39.37768 29.36235 12.85514  1.000 26.43545 ? 35  PHE B CG  1 
ATOM   1104 C CD1 . PHE B 1 36  ? -39.53406 27.99421 13.03672  1.000 27.09876 ? 35  PHE B CD1 1 
ATOM   1105 C CD2 . PHE B 1 36  ? -38.54180 29.80066 11.83799  1.000 26.73741 ? 35  PHE B CD2 1 
ATOM   1106 C CE1 . PHE B 1 36  ? -38.87429 27.08006 12.20705  1.000 26.61902 ? 35  PHE B CE1 1 
ATOM   1107 C CE2 . PHE B 1 36  ? -37.88048 28.89102 10.99804  1.000 24.59046 ? 35  PHE B CE2 1 
ATOM   1108 C CZ  . PHE B 1 36  ? -38.04585 27.53250 11.19083  1.000 26.81634 ? 35  PHE B CZ  1 
ATOM   1109 N N   . LEU B 1 37  ? -37.31848 31.33016 14.75422  1.000 27.30936 ? 36  LEU B N   1 
ATOM   1110 C CA  . LEU B 1 37  ? -35.86117 31.27411 14.69912  1.000 30.31017 ? 36  LEU B CA  1 
ATOM   1111 C C   . LEU B 1 37  ? -35.27274 30.99082 16.07625  1.000 32.24279 ? 36  LEU B C   1 
ATOM   1112 O O   . LEU B 1 37  ? -34.33294 30.19669 16.20778  1.000 29.37160 ? 36  LEU B O   1 
ATOM   1113 C CB  . LEU B 1 37  ? -35.28990 32.57874 14.13344  1.000 30.12026 ? 36  LEU B CB  1 
ATOM   1114 C CG  . LEU B 1 37  ? -35.63102 32.93586 12.67859  1.000 30.52534 ? 36  LEU B CG  1 
ATOM   1115 C CD1 . LEU B 1 37  ? -35.28144 34.38134 12.39422  1.000 25.42548 ? 36  LEU B CD1 1 
ATOM   1116 C CD2 . LEU B 1 37  ? -34.94075 32.00050 11.68976  1.000 27.85876 ? 36  LEU B CD2 1 
ATOM   1117 N N   . ARG B 1 38  ? -35.82480 31.62099 17.11609  1.000 28.82977 ? 37  ARG B N   1 
ATOM   1118 C CA  . ARG B 1 38  ? -35.31707 31.41915 18.46502  1.000 33.06390 ? 37  ARG B CA  1 
ATOM   1119 C C   . ARG B 1 38  ? -35.67945 30.05362 19.02422  1.000 35.51077 ? 37  ARG B C   1 
ATOM   1120 O O   . ARG B 1 38  ? -35.08853 29.63703 20.02796  1.000 31.75212 ? 37  ARG B O   1 
ATOM   1121 C CB  . ARG B 1 38  ? -35.83032 32.52810 19.38306  1.000 31.50464 ? 37  ARG B CB  1 
ATOM   1122 C CG  . ARG B 1 38  ? -35.07210 33.83562 19.18393  1.000 34.04081 ? 37  ARG B CG  1 
ATOM   1123 C CD  . ARG B 1 38  ? -35.50582 34.92156 20.14897  1.000 33.90877 ? 37  ARG B CD  1 
ATOM   1124 N NE  . ARG B 1 38  ? -34.67224 36.11049 20.00551  1.000 35.21315 ? 37  ARG B NE  1 
ATOM   1125 C CZ  . ARG B 1 38  ? -35.13545 37.35332 19.99769  1.000 34.65803 ? 37  ARG B CZ  1 
ATOM   1126 N NH1 . ARG B 1 38  ? -36.42962 37.60982 20.13167  1.000 34.33651 ? 37  ARG B NH1 1 
ATOM   1127 N NH2 . ARG B 1 38  ? -34.28015 38.36344 19.86035  1.000 31.75021 ? 37  ARG B NH2 1 
ATOM   1128 N N   . SER B 1 39  ? -36.61908 29.34285 18.40163  1.000 30.19907 ? 38  SER B N   1 
ATOM   1129 C CA  . SER B 1 39  ? -36.95145 27.99399 18.84569  1.000 29.12490 ? 38  SER B CA  1 
ATOM   1130 C C   . SER B 1 39  ? -36.03181 26.92898 18.26355  1.000 29.33891 ? 38  SER B C   1 
ATOM   1131 O O   . SER B 1 39  ? -36.08600 25.77861 18.70633  1.000 31.17029 ? 38  SER B O   1 
ATOM   1132 C CB  . SER B 1 39  ? -38.39849 27.65329 18.48226  1.000 28.73452 ? 38  SER B CB  1 
ATOM   1133 O OG  . SER B 1 39  ? -38.50668 27.39966 17.09136  1.000 32.84743 ? 38  SER B OG  1 
ATOM   1134 N N   . ILE B 1 40  ? -35.20199 27.26381 17.27604  1.000 30.43470 ? 39  ILE B N   1 
ATOM   1135 C CA  . ILE B 1 40  ? -34.35063 26.24602 16.67700  1.000 30.62742 ? 39  ILE B CA  1 
ATOM   1136 C C   . ILE B 1 40  ? -33.31637 25.79564 17.69916  1.000 34.70934 ? 39  ILE B C   1 
ATOM   1137 O O   . ILE B 1 40  ? -32.55609 26.60698 18.24638  1.000 30.69770 ? 39  ILE B O   1 
ATOM   1138 C CB  . ILE B 1 40  ? -33.69302 26.75876 15.38900  1.000 30.46980 ? 39  ILE B CB  1 
ATOM   1139 C CG1 . ILE B 1 40  ? -34.76076 27.20593 14.37854  1.000 28.54793 ? 39  ILE B CG1 1 
ATOM   1140 C CG2 . ILE B 1 40  ? -32.85955 25.65238 14.77287  1.000 29.17901 ? 39  ILE B CG2 1 
ATOM   1141 C CD1 . ILE B 1 40  ? -34.19490 27.95792 13.18657  1.000 26.52213 ? 39  ILE B CD1 1 
ATOM   1142 N N   . SER B 1 41  ? -33.28249 24.49012 17.95583  1.000 34.51193 ? 40  SER B N   1 
ATOM   1143 C CA  . SER B 1 41  ? -32.62335 23.94058 19.13267  1.000 36.80671 ? 40  SER B CA  1 
ATOM   1144 C C   . SER B 1 41  ? -31.42395 23.06862 18.79347  1.000 38.23806 ? 40  SER B C   1 
ATOM   1145 O O   . SER B 1 41  ? -30.93678 22.34383 19.66611  1.000 40.49279 ? 40  SER B O   1 
ATOM   1146 C CB  . SER B 1 41  ? -33.62801 23.13610 19.95547  1.000 32.82279 ? 40  SER B CB  1 
ATOM   1147 O OG  . SER B 1 41  ? -34.13247 22.07177 19.16683  1.000 36.75608 ? 40  SER B OG  1 
ATOM   1148 N N   . ASP B 1 42  ? -30.93965 23.10622 17.55663  1.000 34.24914 ? 41  ASP B N   1 
ATOM   1149 C CA  . ASP B 1 42  ? -29.76455 22.34600 17.16036  1.000 34.10283 ? 41  ASP B CA  1 
ATOM   1150 C C   . ASP B 1 42  ? -28.75269 23.31204 16.55980  1.000 38.52051 ? 41  ASP B C   1 
ATOM   1151 O O   . ASP B 1 42  ? -28.95550 23.81506 15.44799  1.000 34.64234 ? 41  ASP B O   1 
ATOM   1152 C CB  . ASP B 1 42  ? -30.12871 21.24370 16.16754  1.000 35.01340 ? 41  ASP B CB  1 
ATOM   1153 C CG  . ASP B 1 42  ? -28.94015 20.37553 15.81149  1.000 37.91597 ? 41  ASP B CG  1 
ATOM   1154 O OD1 . ASP B 1 42  ? -27.97691 20.89853 15.21125  1.000 40.97873 ? 41  ASP B OD1 1 
ATOM   1155 O OD2 . ASP B 1 42  ? -28.97023 19.16860 16.12127  1.000 46.18917 ? 41  ASP B OD2 1 
ATOM   1156 N N   . ALA B 1 43  ? -27.64907 23.54387 17.28026  1.000 36.99853 ? 42  ALA B N   1 
ATOM   1157 C CA  . ALA B 1 43  ? -26.64637 24.50212 16.81838  1.000 37.15016 ? 42  ALA B CA  1 
ATOM   1158 C C   . ALA B 1 43  ? -26.07189 24.10936 15.46731  1.000 33.67966 ? 42  ALA B C   1 
ATOM   1159 O O   . ALA B 1 43  ? -25.76263 24.98372 14.64628  1.000 32.66590 ? 42  ALA B O   1 
ATOM   1160 C CB  . ALA B 1 43  ? -25.51454 24.63734 17.84509  1.000 36.42683 ? 42  ALA B CB  1 
ATOM   1161 N N   . ARG B 1 44  ? -25.92565 22.80773 15.21141  1.000 33.74681 ? 43  ARG B N   1 
ATOM   1162 C CA  . ARG B 1 44  ? -25.31517 22.37703 13.95647  1.000 36.67798 ? 43  ARG B CA  1 
ATOM   1163 C C   . ARG B 1 44  ? -26.21636 22.68853 12.75862  1.000 34.56147 ? 43  ARG B C   1 
ATOM   1164 O O   . ARG B 1 44  ? -25.72345 23.04793 11.68413  1.000 34.90967 ? 43  ARG B O   1 
ATOM   1165 C CB  . ARG B 1 44  ? -24.98031 20.88467 14.02692  1.000 40.00662 ? 43  ARG B CB  1 
ATOM   1166 C CG  . ARG B 1 44  ? -24.37384 20.30243 12.75068  1.000 48.28056 ? 43  ARG B CG  1 
ATOM   1167 C CD  . ARG B 1 44  ? -23.20197 21.13612 12.22099  1.000 52.50550 ? 43  ARG B CD  1 
ATOM   1168 N NE  . ARG B 1 44  ? -21.96981 20.80188 12.92727  1.000 63.98367 ? 43  ARG B NE  1 
ATOM   1169 C CZ  . ARG B 1 44  ? -21.31074 19.65639 12.79454  1.000 65.92006 ? 43  ARG B CZ  1 
ATOM   1170 N NH1 . ARG B 1 44  ? -21.68790 18.73646 11.91793  1.000 63.63602 ? 43  ARG B NH1 1 
ATOM   1171 N NH2 . ARG B 1 44  ? -20.24652 19.42759 13.56202  1.000 64.39606 ? 43  ARG B NH2 1 
ATOM   1172 N N   . VAL B 1 45  ? -27.53538 22.57009 12.92030  1.000 32.06390 ? 44  VAL B N   1 
ATOM   1173 C CA  . VAL B 1 45  ? -28.43619 22.92253 11.82213  1.000 35.50103 ? 44  VAL B CA  1 
ATOM   1174 C C   . VAL B 1 45  ? -28.41380 24.42923 11.56495  1.000 34.41193 ? 44  VAL B C   1 
ATOM   1175 O O   . VAL B 1 45  ? -28.46716 24.87909 10.41169  1.000 32.91587 ? 44  VAL B O   1 
ATOM   1176 C CB  . VAL B 1 45  ? -29.86256 22.41901 12.11677  1.000 33.96168 ? 44  VAL B CB  1 
ATOM   1177 C CG1 . VAL B 1 45  ? -30.80491 22.77555 10.97117  1.000 35.18077 ? 44  VAL B CG1 1 
ATOM   1178 C CG2 . VAL B 1 45  ? -29.85759 20.91168 12.34689  1.000 35.45546 ? 44  VAL B CG2 1 
ATOM   1179 N N   . ILE B 1 46  ? -28.35457 25.23387 12.62950  1.000 31.42906 ? 45  ILE B N   1 
ATOM   1180 C CA  . ILE B 1 46  ? -28.30248 26.68430 12.46086  1.000 30.27975 ? 45  ILE B CA  1 
ATOM   1181 C C   . ILE B 1 46  ? -27.03263 27.07858 11.72465  1.000 32.33995 ? 45  ILE B C   1 
ATOM   1182 O O   . ILE B 1 46  ? -27.06362 27.85721 10.76552  1.000 31.14157 ? 45  ILE B O   1 
ATOM   1183 C CB  . ILE B 1 46  ? -28.40414 27.38876 13.82538  1.000 28.19228 ? 45  ILE B CB  1 
ATOM   1184 C CG1 . ILE B 1 46  ? -29.78904 27.17426 14.42657  1.000 28.00649 ? 45  ILE B CG1 1 
ATOM   1185 C CG2 . ILE B 1 46  ? -28.10354 28.87421 13.68872  1.000 26.34385 ? 45  ILE B CG2 1 
ATOM   1186 C CD1 . ILE B 1 46  ? -29.87274 27.47705 15.90557  1.000 34.61838 ? 45  ILE B CD1 1 
ATOM   1187 N N   . ILE B 1 47  ? -25.89847 26.51579 12.14787  1.000 32.24142 ? 46  ILE B N   1 
ATOM   1188 C CA  . ILE B 1 47  ? -24.60933 26.87322 11.55800  1.000 31.32673 ? 46  ILE B CA  1 
ATOM   1189 C C   . ILE B 1 47  ? -24.56540 26.48759 10.08503  1.000 32.03004 ? 46  ILE B C   1 
ATOM   1190 O O   . ILE B 1 47  ? -24.11917 27.26955 9.23719   1.000 30.68496 ? 46  ILE B O   1 
ATOM   1191 C CB  . ILE B 1 47  ? -23.46215 26.21969 12.35291  1.000 32.05605 ? 46  ILE B CB  1 
ATOM   1192 C CG1 . ILE B 1 47  ? -23.33429 26.88559 13.72611  1.000 32.59837 ? 46  ILE B CG1 1 
ATOM   1193 C CG2 . ILE B 1 47  ? -22.16126 26.31983 11.59437  1.000 30.55603 ? 46  ILE B CG2 1 
ATOM   1194 C CD1 . ILE B 1 47  ? -22.52987 26.09768 14.70936  1.000 32.03333 ? 46  ILE B CD1 1 
ATOM   1195 N N   . ASP B 1 48  ? -25.02404 25.27157 9.75998   1.000 32.88651 ? 47  ASP B N   1 
ATOM   1196 C CA  . ASP B 1 48  ? -24.97510 24.77811 8.38245   1.000 29.87239 ? 47  ASP B CA  1 
ATOM   1197 C C   . ASP B 1 48  ? -25.85465 25.59807 7.44898   1.000 31.98122 ? 47  ASP B C   1 
ATOM   1198 O O   . ASP B 1 48  ? -25.55368 25.71692 6.25294   1.000 29.75498 ? 47  ASP B O   1 
ATOM   1199 C CB  . ASP B 1 48  ? -25.42230 23.31672 8.32582   1.000 37.19137 ? 47  ASP B CB  1 
ATOM   1200 C CG  . ASP B 1 48  ? -24.37905 22.35089 8.86650   1.000 40.95179 ? 47  ASP B CG  1 
ATOM   1201 O OD1 . ASP B 1 48  ? -23.20285 22.74423 9.04097   1.000 42.85155 ? 47  ASP B OD1 1 
ATOM   1202 O OD2 . ASP B 1 48  ? -24.74896 21.18521 9.11335   1.000 45.52812 ? 47  ASP B OD2 1 
ATOM   1203 N N   . ASN B 1 49  ? -26.94085 26.16731 7.96919   1.000 30.58583 ? 48  ASN B N   1 
ATOM   1204 C CA  . ASN B 1 49  ? -27.87825 26.93291 7.16273   1.000 31.00690 ? 48  ASN B CA  1 
ATOM   1205 C C   . ASN B 1 49  ? -27.75091 28.43740 7.36190   1.000 34.38054 ? 48  ASN B C   1 
ATOM   1206 O O   . ASN B 1 49  ? -28.63367 29.18394 6.91399   1.000 33.60578 ? 48  ASN B O   1 
ATOM   1207 C CB  . ASN B 1 49  ? -29.30733 26.47256 7.45827   1.000 27.96119 ? 48  ASN B CB  1 
ATOM   1208 C CG  . ASN B 1 49  ? -29.55901 25.04896 6.98709   1.000 30.16740 ? 48  ASN B CG  1 
ATOM   1209 O OD1 . ASN B 1 49  ? -29.72087 24.79967 5.79406   1.000 30.51585 ? 48  ASN B OD1 1 
ATOM   1210 N ND2 . ASN B 1 49  ? -29.57381 24.10785 7.92085   1.000 29.23180 ? 48  ASN B ND2 1 
ATOM   1211 N N   . ARG B 1 50  ? -26.66081 28.90384 7.99064   1.000 32.84979 ? 49  ARG B N   1 
ATOM   1212 C CA  . ARG B 1 50  ? -26.53708 30.32572 8.30725   1.000 30.84789 ? 49  ARG B CA  1 
ATOM   1213 C C   . ARG B 1 50  ? -26.57606 31.18372 7.05197   1.000 29.39753 ? 49  ARG B C   1 
ATOM   1214 O O   . ARG B 1 50  ? -27.12307 32.28958 7.06903   1.000 33.88666 ? 49  ARG B O   1 
ATOM   1215 C CB  . ARG B 1 50  ? -25.24287 30.60250 9.07676   1.000 34.32875 ? 49  ARG B CB  1 
ATOM   1216 C CG  . ARG B 1 50  ? -23.96784 30.31934 8.29066   1.000 32.22726 ? 49  ARG B CG  1 
ATOM   1217 C CD  . ARG B 1 50  ? -22.75615 30.36532 9.20180   1.000 36.41479 ? 49  ARG B CD  1 
ATOM   1218 N NE  . ARG B 1 50  ? -21.50547 30.27263 8.46241   1.000 35.93899 ? 49  ARG B NE  1 
ATOM   1219 C CZ  . ARG B 1 50  ? -20.93942 29.12719 8.11269   1.000 38.04004 ? 49  ARG B CZ  1 
ATOM   1220 N NH1 . ARG B 1 50  ? -21.50353 27.96614 8.39764   1.000 37.68986 ? 49  ARG B NH1 1 
ATOM   1221 N NH2 . ARG B 1 50  ? -19.77880 29.14677 7.46387   1.000 36.57452 ? 49  ARG B NH2 1 
ATOM   1222 N N   . ASN B 1 51  ? -25.99388 30.70419 5.95556   1.000 27.21454 ? 50  ASN B N   1 
ATOM   1223 C CA  . ASN B 1 51  ? -26.01463 31.50484 4.73939   1.000 33.18721 ? 50  ASN B CA  1 
ATOM   1224 C C   . ASN B 1 51  ? -27.31154 31.32425 3.96641   1.000 34.24094 ? 50  ASN B C   1 
ATOM   1225 O O   . ASN B 1 51  ? -27.80942 32.28711 3.37427   1.000 32.22125 ? 50  ASN B O   1 
ATOM   1226 C CB  . ASN B 1 51  ? -24.80638 31.17278 3.86669   1.000 33.69155 ? 50  ASN B CB  1 
ATOM   1227 C CG  . ASN B 1 51  ? -23.49439 31.57990 4.52202   1.000 40.65867 ? 50  ASN B CG  1 
ATOM   1228 O OD1 . ASN B 1 51  ? -23.36796 32.70297 5.02501   1.000 39.54741 ? 50  ASN B OD1 1 
ATOM   1229 N ND2 . ASN B 1 51  ? -22.52342 30.66737 4.54387   1.000 34.72986 ? 50  ASN B ND2 1 
ATOM   1230 N N   . LEU B 1 52  ? -27.89319 30.12389 3.99439   1.000 29.19346 ? 51  LEU B N   1 
ATOM   1231 C CA  . LEU B 1 52  ? -29.10641 29.89759 3.22086   1.000 32.54413 ? 51  LEU B CA  1 
ATOM   1232 C C   . LEU B 1 52  ? -30.27698 30.69643 3.77381   1.000 29.86516 ? 51  LEU B C   1 
ATOM   1233 O O   . LEU B 1 52  ? -31.10637 31.19561 3.00398   1.000 28.61505 ? 51  LEU B O   1 
ATOM   1234 C CB  . LEU B 1 52  ? -29.44182 28.41169 3.17983   1.000 32.35991 ? 51  LEU B CB  1 
ATOM   1235 C CG  . LEU B 1 52  ? -28.42788 27.53021 2.45888   1.000 35.10272 ? 51  LEU B CG  1 
ATOM   1236 C CD1 . LEU B 1 52  ? -28.66159 26.05420 2.84104   1.000 36.62803 ? 51  LEU B CD1 1 
ATOM   1237 C CD2 . LEU B 1 52  ? -28.50108 27.75475 0.95122   1.000 32.35047 ? 51  LEU B CD2 1 
ATOM   1238 N N   . ILE B 1 53  ? -30.35961 30.84031 5.10204   1.000 28.89846 ? 52  ILE B N   1 
ATOM   1239 C CA  . ILE B 1 53  ? -31.48758 31.55448 5.69698   1.000 26.80918 ? 52  ILE B CA  1 
ATOM   1240 C C   . ILE B 1 53  ? -31.28631 33.05806 5.73114   1.000 31.66863 ? 52  ILE B C   1 
ATOM   1241 O O   . ILE B 1 53  ? -32.23410 33.78602 6.06039   1.000 29.47866 ? 52  ILE B O   1 
ATOM   1242 C CB  . ILE B 1 53  ? -31.79380 31.08919 7.13514   1.000 28.76295 ? 52  ILE B CB  1 
ATOM   1243 C CG1 . ILE B 1 53  ? -30.64034 31.42870 8.08792   1.000 31.06931 ? 52  ILE B CG1 1 
ATOM   1244 C CG2 . ILE B 1 53  ? -32.12076 29.60129 7.17512   1.000 28.65112 ? 52  ILE B CG2 1 
ATOM   1245 C CD1 . ILE B 1 53  ? -31.04787 31.39713 9.55858   1.000 33.41884 ? 52  ILE B CD1 1 
ATOM   1246 N N   . HIS B 1 54  ? -30.09446 33.54578 5.37856   1.000 29.80026 ? 53  HIS B N   1 
ATOM   1247 C CA  . HIS B 1 54  ? -29.73597 34.92264 5.68779   1.000 29.53730 ? 53  HIS B CA  1 
ATOM   1248 C C   . HIS B 1 54  ? -30.68127 35.91407 5.01678   1.000 34.17220 ? 53  HIS B C   1 
ATOM   1249 O O   . HIS B 1 54  ? -30.96894 35.81496 3.81969   1.000 30.98237 ? 53  HIS B O   1 
ATOM   1250 C CB  . HIS B 1 54  ? -28.30039 35.21231 5.26203   1.000 32.40330 ? 53  HIS B CB  1 
ATOM   1251 C CG  . HIS B 1 54  ? -27.88913 36.62896 5.51432   1.000 36.19687 ? 53  HIS B CG  1 
ATOM   1252 N ND1 . HIS B 1 54  ? -27.95961 37.20907 6.76508   1.000 34.28462 ? 53  HIS B ND1 1 
ATOM   1253 C CD2 . HIS B 1 54  ? -27.43125 37.59029 4.67796   1.000 33.63508 ? 53  HIS B CD2 1 
ATOM   1254 C CE1 . HIS B 1 54  ? -27.54951 38.46291 6.68918   1.000 33.16671 ? 53  HIS B CE1 1 
ATOM   1255 N NE2 . HIS B 1 54  ? -27.22841 38.72091 5.43290   1.000 37.09701 ? 53  HIS B NE2 1 
ATOM   1256 N N   . PHE B 1 55  ? -31.14758 36.88517 5.79241   1.000 31.35326 ? 54  PHE B N   1 
ATOM   1257 C CA  . PHE B 1 55  ? -32.05489 37.91775 5.31181   1.000 33.18438 ? 54  PHE B CA  1 
ATOM   1258 C C   . PHE B 1 55  ? -31.26101 39.19398 5.02385   1.000 37.64087 ? 54  PHE B C   1 
ATOM   1259 O O   . PHE B 1 55  ? -30.64064 39.75667 5.93507   1.000 34.64376 ? 54  PHE B O   1 
ATOM   1260 C CB  . PHE B 1 55  ? -33.14558 38.17323 6.35309   1.000 30.62419 ? 54  PHE B CB  1 
ATOM   1261 C CG  . PHE B 1 55  ? -34.24140 39.06070 5.86685   1.000 31.50164 ? 54  PHE B CG  1 
ATOM   1262 C CD1 . PHE B 1 55  ? -34.10745 40.43877 5.92574   1.000 31.33172 ? 54  PHE B CD1 1 
ATOM   1263 C CD2 . PHE B 1 55  ? -35.40332 38.52059 5.33868   1.000 30.03904 ? 54  PHE B CD2 1 
ATOM   1264 C CE1 . PHE B 1 55  ? -35.10946 41.26736 5.46502   1.000 32.57846 ? 54  PHE B CE1 1 
ATOM   1265 C CE2 . PHE B 1 55  ? -36.41398 39.33412 4.87869   1.000 30.17737 ? 54  PHE B CE2 1 
ATOM   1266 C CZ  . PHE B 1 55  ? -36.27163 40.71682 4.93532   1.000 30.60128 ? 54  PHE B CZ  1 
ATOM   1267 N N   . GLN B 1 56  ? -31.28448 39.65350 3.76561   1.000 35.51104 ? 55  GLN B N   1 
ATOM   1268 C CA  . GLN B 1 56  ? -30.50462 40.82028 3.35675   1.000 36.91306 ? 55  GLN B CA  1 
ATOM   1269 C C   . GLN B 1 56  ? -31.30002 42.09133 3.61791   1.000 39.69547 ? 55  GLN B C   1 
ATOM   1270 O O   . GLN B 1 56  ? -32.38305 42.28888 3.04652   1.000 38.25219 ? 55  GLN B O   1 
ATOM   1271 C CB  . GLN B 1 56  ? -30.09599 40.74246 1.88712   1.000 35.64438 ? 55  GLN B CB  1 
ATOM   1272 C CG  . GLN B 1 56  ? -28.99154 39.73703 1.64839   1.000 42.23273 ? 55  GLN B CG  1 
ATOM   1273 C CD  . GLN B 1 56  ? -28.70385 39.49247 0.17624   1.000 50.87390 ? 55  GLN B CD  1 
ATOM   1274 O OE1 . GLN B 1 56  ? -28.71875 38.35185 -0.28166  1.000 54.04794 ? 55  GLN B OE1 1 
ATOM   1275 N NE2 . GLN B 1 56  ? -28.40035 40.55859 -0.56153  1.000 50.31806 ? 55  GLN B NE2 1 
ATOM   1276 N N   . SER B 1 57  ? -30.74612 42.96161 4.47071   1.000 38.02720 ? 56  SER B N   1 
ATOM   1277 C CA  . SER B 1 57  ? -31.39220 44.22933 4.79771   1.000 38.27106 ? 56  SER B CA  1 
ATOM   1278 C C   . SER B 1 57  ? -31.37848 45.20407 3.63321   1.000 35.55324 ? 56  SER B C   1 
ATOM   1279 O O   . SER B 1 57  ? -32.17889 46.14155 3.61688   1.000 40.45391 ? 56  SER B O   1 
ATOM   1280 C CB  . SER B 1 57  ? -30.72627 44.87223 6.01376   1.000 42.13119 ? 56  SER B CB  1 
ATOM   1281 O OG  . SER B 1 57  ? -30.95046 44.07400 7.16200   1.000 45.06373 ? 56  SER B OG  1 
ATOM   1282 N N   . SER B 1 58  ? -30.49815 45.01390 2.66408   1.000 35.76069 ? 57  SER B N   1 
ATOM   1283 C CA  . SER B 1 58  ? -30.63676 45.70880 1.39406   1.000 46.37196 ? 57  SER B CA  1 
ATOM   1284 C C   . SER B 1 58  ? -31.65962 44.96341 0.53438   1.000 46.39205 ? 57  SER B C   1 
ATOM   1285 O O   . SER B 1 58  ? -31.53720 43.75875 0.30638   1.000 55.59945 ? 57  SER B O   1 
ATOM   1286 C CB  . SER B 1 58  ? -29.27651 45.79778 0.70258   1.000 44.88679 ? 57  SER B CB  1 
ATOM   1287 O OG  . SER B 1 58  ? -28.78202 44.50007 0.43353   1.000 53.61073 ? 57  SER B OG  1 
ATOM   1288 N N   . GLY B 1 59  ? -32.69956 45.64911 0.10760   1.000 42.19463 ? 58  GLY B N   1 
ATOM   1289 C CA  . GLY B 1 59  ? -33.72359 44.96770 -0.66468  1.000 33.58607 ? 58  GLY B CA  1 
ATOM   1290 C C   . GLY B 1 59  ? -34.63554 44.09285 0.17486   1.000 32.02235 ? 58  GLY B C   1 
ATOM   1291 O O   . GLY B 1 59  ? -34.66955 42.86499 0.01445   1.000 30.80323 ? 58  GLY B O   1 
ATOM   1292 N N   . ILE B 1 60  ? -35.42583 44.72509 1.04894   1.000 28.40072 ? 59  ILE B N   1 
ATOM   1293 C CA  . ILE B 1 60  ? -36.27286 43.96310 1.96496   1.000 28.85188 ? 59  ILE B CA  1 
ATOM   1294 C C   . ILE B 1 60  ? -37.33508 43.19020 1.19985   1.000 26.31424 ? 59  ILE B C   1 
ATOM   1295 O O   . ILE B 1 60  ? -37.59436 42.01184 1.48741   1.000 23.93550 ? 59  ILE B O   1 
ATOM   1296 C CB  . ILE B 1 60  ? -36.88280 44.89491 3.03396   1.000 29.11938 ? 59  ILE B CB  1 
ATOM   1297 C CG1 . ILE B 1 60  ? -35.74117 45.48294 3.88544   1.000 28.00799 ? 59  ILE B CG1 1 
ATOM   1298 C CG2 . ILE B 1 60  ? -37.91716 44.16159 3.86909   1.000 24.76062 ? 59  ILE B CG2 1 
ATOM   1299 C CD1 . ILE B 1 60  ? -36.19087 46.52953 4.87621   1.000 32.54946 ? 59  ILE B CD1 1 
ATOM   1300 N N   . SER B 1 61  ? -37.94519 43.82923 0.18945   1.000 25.52152 ? 60  SER B N   1 
ATOM   1301 C CA  . SER B 1 61  ? -39.00935 43.17948 -0.57043  1.000 29.14616 ? 60  SER B CA  1 
ATOM   1302 C C   . SER B 1 61  ? -38.51695 41.88853 -1.21499  1.000 25.94148 ? 60  SER B C   1 
ATOM   1303 O O   . SER B 1 61  ? -39.15480 40.83600 -1.08508  1.000 24.66475 ? 60  SER B O   1 
ATOM   1304 C CB  . SER B 1 61  ? -39.57477 44.14052 -1.61703  1.000 25.19503 ? 60  SER B CB  1 
ATOM   1305 O OG  . SER B 1 61  ? -40.31100 45.15694 -0.95968  1.000 26.53051 ? 60  SER B OG  1 
ATOM   1306 N N   . TYR B 1 62  ? -37.35953 41.93659 -1.88714  1.000 24.85605 ? 61  TYR B N   1 
ATOM   1307 C CA  . TYR B 1 62  ? -36.85601 40.71339 -2.50145  1.000 24.29958 ? 61  TYR B CA  1 
ATOM   1308 C C   . TYR B 1 62  ? -36.43151 39.70014 -1.44850  1.000 25.18035 ? 61  TYR B C   1 
ATOM   1309 O O   . TYR B 1 62  ? -36.65951 38.49727 -1.61927  1.000 26.19743 ? 61  TYR B O   1 
ATOM   1310 C CB  . TYR B 1 62  ? -35.69918 41.00057 -3.45924  1.000 26.81951 ? 61  TYR B CB  1 
ATOM   1311 C CG  . TYR B 1 62  ? -35.33867 39.73864 -4.22182  1.000 29.85537 ? 61  TYR B CG  1 
ATOM   1312 C CD1 . TYR B 1 62  ? -36.30847 39.06178 -4.95373  1.000 27.77594 ? 61  TYR B CD1 1 
ATOM   1313 C CD2 . TYR B 1 62  ? -34.06201 39.19611 -4.16829  1.000 28.96639 ? 61  TYR B CD2 1 
ATOM   1314 C CE1 . TYR B 1 62  ? -36.01629 37.89326 -5.63280  1.000 28.71293 ? 61  TYR B CE1 1 
ATOM   1315 C CE2 . TYR B 1 62  ? -33.75269 38.02427 -4.85146  1.000 29.08653 ? 61  TYR B CE2 1 
ATOM   1316 C CZ  . TYR B 1 62  ? -34.74152 37.37755 -5.58403  1.000 30.08352 ? 61  TYR B CZ  1 
ATOM   1317 O OH  . TYR B 1 62  ? -34.48690 36.20620 -6.27141  1.000 29.06062 ? 61  TYR B OH  1 
ATOM   1318 N N   . SER B 1 63  ? -35.81789 40.15833 -0.35109  1.000 24.78271 ? 62  SER B N   1 
ATOM   1319 C CA  . SER B 1 63  ? -35.44745 39.22559 0.71343   1.000 26.70200 ? 62  SER B CA  1 
ATOM   1320 C C   . SER B 1 63  ? -36.67003 38.48412 1.23535   1.000 25.71936 ? 62  SER B C   1 
ATOM   1321 O O   . SER B 1 63  ? -36.61493 37.27135 1.46940   1.000 23.18267 ? 62  SER B O   1 
ATOM   1322 C CB  . SER B 1 63  ? -34.74227 39.96204 1.85032   1.000 26.53498 ? 62  SER B CB  1 
ATOM   1323 O OG  . SER B 1 63  ? -33.43809 40.35600 1.48064   1.000 29.84580 ? 62  SER B OG  1 
ATOM   1324 N N   . LEU B 1 64  ? -37.78790 39.19515 1.41693   1.000 24.07857 ? 63  LEU B N   1 
ATOM   1325 C CA  . LEU B 1 64  ? -39.02192 38.54346 1.84140   1.000 24.02174 ? 63  LEU B CA  1 
ATOM   1326 C C   . LEU B 1 64  ? -39.53609 37.57407 0.78407   1.000 25.17113 ? 63  LEU B C   1 
ATOM   1327 O O   . LEU B 1 64  ? -39.95163 36.45224 1.10427   1.000 26.66355 ? 63  LEU B O   1 
ATOM   1328 C CB  . LEU B 1 64  ? -40.08678 39.59086 2.14252   1.000 24.11112 ? 63  LEU B CB  1 
ATOM   1329 C CG  . LEU B 1 64  ? -39.94711 40.40699 3.41899   1.000 27.17977 ? 63  LEU B CG  1 
ATOM   1330 C CD1 . LEU B 1 64  ? -40.97808 41.53160 3.39719   1.000 24.25078 ? 63  LEU B CD1 1 
ATOM   1331 C CD2 . LEU B 1 64  ? -40.13552 39.49775 4.62414   1.000 20.94454 ? 63  LEU B CD2 1 
ATOM   1332 N N   . GLU B 1 65  ? -39.53485 37.99940 -0.47653  1.000 24.17324 ? 64  GLU B N   1 
ATOM   1333 C CA  . GLU B 1 65  ? -40.14092 37.20464 -1.53700  1.000 25.90944 ? 64  GLU B CA  1 
ATOM   1334 C C   . GLU B 1 65  ? -39.34309 35.94192 -1.81572  1.000 25.08986 ? 64  GLU B C   1 
ATOM   1335 O O   . GLU B 1 65  ? -39.91930 34.90285 -2.15497  1.000 23.40534 ? 64  GLU B O   1 
ATOM   1336 C CB  . GLU B 1 65  ? -40.25621 38.03585 -2.81456  1.000 23.40340 ? 64  GLU B CB  1 
ATOM   1337 C CG  . GLU B 1 65  ? -41.28383 37.48924 -3.77868  1.000 26.84005 ? 64  GLU B CG  1 
ATOM   1338 C CD  . GLU B 1 65  ? -41.68559 38.50061 -4.81208  1.000 27.48442 ? 64  GLU B CD  1 
ATOM   1339 O OE1 . GLU B 1 65  ? -41.01908 38.53673 -5.87175  1.000 25.53970 ? 64  GLU B OE1 1 
ATOM   1340 O OE2 . GLU B 1 65  ? -42.64771 39.26928 -4.55794  1.000 26.78189 ? 64  GLU B OE2 1 
ATOM   1341 N N   . SER B 1 66  ? -38.01686 36.01985 -1.69318  1.000 24.73684 ? 65  SER B N   1 
ATOM   1342 C CA  . SER B 1 66  ? -37.12463 34.92265 -2.04221  1.000 24.64843 ? 65  SER B CA  1 
ATOM   1343 C C   . SER B 1 66  ? -36.66492 34.09481 -0.84855  1.000 25.81782 ? 65  SER B C   1 
ATOM   1344 O O   . SER B 1 66  ? -35.98302 33.08686 -1.05429  1.000 24.17322 ? 65  SER B O   1 
ATOM   1345 C CB  . SER B 1 66  ? -35.89054 35.47445 -2.75658  1.000 27.51690 ? 65  SER B CB  1 
ATOM   1346 O OG  . SER B 1 66  ? -35.04560 36.11199 -1.81446  1.000 27.88449 ? 65  SER B OG  1 
ATOM   1347 N N   . SER B 1 67  ? -36.99941 34.49790 0.38040   1.000 25.35033 ? 66  SER B N   1 
ATOM   1348 C CA  . SER B 1 67  ? -36.55325 33.77943 1.56406   1.000 22.91912 ? 66  SER B CA  1 
ATOM   1349 C C   . SER B 1 67  ? -36.92508 32.28496 1.47120   1.000 27.01178 ? 66  SER B C   1 
ATOM   1350 O O   . SER B 1 67  ? -38.06725 31.95816 1.13233   1.000 25.24841 ? 66  SER B O   1 
ATOM   1351 C CB  . SER B 1 67  ? -37.18861 34.36251 2.82504   1.000 25.21742 ? 66  SER B CB  1 
ATOM   1352 O OG  . SER B 1 67  ? -36.84992 33.57513 3.96111   1.000 24.18547 ? 66  SER B OG  1 
ATOM   1353 N N   . PRO B 1 68  ? -36.00094 31.38859 1.81317   1.000 25.98814 ? 67  PRO B N   1 
ATOM   1354 C CA  . PRO B 1 68  ? -36.37657 29.96092 1.88730   1.000 23.39578 ? 67  PRO B CA  1 
ATOM   1355 C C   . PRO B 1 68  ? -37.36679 29.65635 2.98930   1.000 26.03558 ? 67  PRO B C   1 
ATOM   1356 O O   . PRO B 1 68  ? -37.91890 28.54574 2.99738   1.000 26.19114 ? 67  PRO B O   1 
ATOM   1357 C CB  . PRO B 1 68  ? -35.03508 29.24201 2.13476   1.000 27.46320 ? 67  PRO B CB  1 
ATOM   1358 C CG  . PRO B 1 68  ? -34.07497 30.28625 2.57111   1.000 29.41908 ? 67  PRO B CG  1 
ATOM   1359 C CD  . PRO B 1 68  ? -34.58645 31.63239 2.13488   1.000 27.18620 ? 67  PRO B CD  1 
ATOM   1360 N N   . LEU B 1 69  ? -37.60759 30.58075 3.92966   1.000 21.08555 ? 68  LEU B N   1 
ATOM   1361 C CA  . LEU B 1 69  ? -38.67364 30.34909 4.89890   1.000 25.26463 ? 68  LEU B CA  1 
ATOM   1362 C C   . LEU B 1 69  ? -40.05210 30.32308 4.23330   1.000 27.34661 ? 68  LEU B C   1 
ATOM   1363 O O   . LEU B 1 69  ? -41.01795 29.88803 4.87071   1.000 24.83790 ? 68  LEU B O   1 
ATOM   1364 C CB  . LEU B 1 69  ? -38.62189 31.40989 6.01803   1.000 24.07202 ? 68  LEU B CB  1 
ATOM   1365 C CG  . LEU B 1 69  ? -37.69621 31.13709 7.21987   1.000 24.71285 ? 68  LEU B CG  1 
ATOM   1366 C CD1 . LEU B 1 69  ? -36.26482 30.91306 6.79305   1.000 25.20135 ? 68  LEU B CD1 1 
ATOM   1367 C CD2 . LEU B 1 69  ? -37.73902 32.27668 8.27438   1.000 26.63542 ? 68  LEU B CD2 1 
ATOM   1368 N N   . ASN B 1 70  ? -40.15254 30.76425 2.96839   1.000 23.16544 ? 69  ASN B N   1 
ATOM   1369 C CA  . ASN B 1 70  ? -41.35659 30.59719 2.15066   1.000 29.55648 ? 69  ASN B CA  1 
ATOM   1370 C C   . ASN B 1 70  ? -41.60849 29.15023 1.75131   1.000 26.06762 ? 69  ASN B C   1 
ATOM   1371 O O   . ASN B 1 70  ? -42.72318 28.83197 1.32115   1.000 26.81345 ? 69  ASN B O   1 
ATOM   1372 C CB  . ASN B 1 70  ? -41.25374 31.40137 0.84724   1.000 21.72928 ? 69  ASN B CB  1 
ATOM   1373 C CG  . ASN B 1 70  ? -41.40904 32.89745 1.05868   1.000 25.62848 ? 69  ASN B CG  1 
ATOM   1374 O OD1 . ASN B 1 70  ? -42.46995 33.36882 1.45809   1.000 22.95765 ? 69  ASN B OD1 1 
ATOM   1375 N ND2 . ASN B 1 70  ? -40.34099 33.65323 0.78140   1.000 21.83086 ? 69  ASN B ND2 1 
ATOM   1376 N N   . SER B 1 71  ? -40.59929 28.28213 1.84944   1.000 23.10362 ? 70  SER B N   1 
ATOM   1377 C CA  . SER B 1 71  ? -40.64177 26.96765 1.20978   1.000 25.48602 ? 70  SER B CA  1 
ATOM   1378 C C   . SER B 1 71  ? -40.86548 25.85615 2.23283   1.000 26.21060 ? 70  SER B C   1 
ATOM   1379 O O   . SER B 1 71  ? -39.99668 25.61790 3.08774   1.000 25.44403 ? 70  SER B O   1 
ATOM   1380 C CB  . SER B 1 71  ? -39.34230 26.74042 0.43380   1.000 24.55194 ? 70  SER B CB  1 
ATOM   1381 O OG  . SER B 1 71  ? -39.09451 25.38106 0.15127   1.000 21.04840 ? 70  SER B OG  1 
ATOM   1382 N N   . PRO B 1 72  ? -42.00266 25.15987 2.19985   1.000 26.74065 ? 71  PRO B N   1 
ATOM   1383 C CA  . PRO B 1 72  ? -42.17781 24.01376 3.10870   1.000 24.76134 ? 71  PRO B CA  1 
ATOM   1384 C C   . PRO B 1 72  ? -41.10831 22.94444 2.93612   1.000 26.53907 ? 71  PRO B C   1 
ATOM   1385 O O   . PRO B 1 72  ? -40.70714 22.32364 3.93184   1.000 23.50726 ? 71  PRO B O   1 
ATOM   1386 C CB  . PRO B 1 72  ? -43.57631 23.48048 2.75664   1.000 26.88644 ? 71  PRO B CB  1 
ATOM   1387 C CG  . PRO B 1 72  ? -44.21812 24.53929 1.91897   1.000 28.48979 ? 71  PRO B CG  1 
ATOM   1388 C CD  . PRO B 1 72  ? -43.14263 25.35044 1.28887   1.000 25.15830 ? 71  PRO B CD  1 
ATOM   1389 N N   . ILE B 1 73  ? -40.61332 22.72100 1.71195   1.000 23.75387 ? 72  ILE B N   1 
ATOM   1390 C CA  . ILE B 1 73  ? -39.56317 21.71999 1.53813   1.000 26.46194 ? 72  ILE B CA  1 
ATOM   1391 C C   . ILE B 1 73  ? -38.30158 22.12676 2.29500   1.000 28.64373 ? 72  ILE B C   1 
ATOM   1392 O O   . ILE B 1 73  ? -37.67404 21.30129 2.96536   1.000 25.47101 ? 72  ILE B O   1 
ATOM   1393 C CB  . ILE B 1 73  ? -39.25979 21.47757 0.04975   1.000 23.46430 ? 72  ILE B CB  1 
ATOM   1394 C CG1 . ILE B 1 73  ? -40.41444 20.74078 -0.63446  1.000 24.76514 ? 72  ILE B CG1 1 
ATOM   1395 C CG2 . ILE B 1 73  ? -37.96558 20.66915 -0.10561  1.000 23.67369 ? 72  ILE B CG2 1 
ATOM   1396 C CD1 . ILE B 1 73  ? -40.33693 20.76968 -2.17958  1.000 22.30227 ? 72  ILE B CD1 1 
ATOM   1397 N N   . PHE B 1 74  ? -37.89072 23.39192 2.17440   1.000 23.99697 ? 73  PHE B N   1 
ATOM   1398 C CA  . PHE B 1 74  ? -36.71659 23.85235 2.90637   1.000 26.82460 ? 73  PHE B CA  1 
ATOM   1399 C C   . PHE B 1 74  ? -36.91351 23.69985 4.41177   1.000 26.84092 ? 73  PHE B C   1 
ATOM   1400 O O   . PHE B 1 74  ? -36.01648 23.22397 5.12106   1.000 27.44913 ? 73  PHE B O   1 
ATOM   1401 C CB  . PHE B 1 74  ? -36.42489 25.30997 2.54568   1.000 27.25184 ? 73  PHE B CB  1 
ATOM   1402 C CG  . PHE B 1 74  ? -35.26400 25.90640 3.29794   1.000 27.66157 ? 73  PHE B CG  1 
ATOM   1403 C CD1 . PHE B 1 74  ? -33.96842 25.80118 2.79978   1.000 28.81615 ? 73  PHE B CD1 1 
ATOM   1404 C CD2 . PHE B 1 74  ? -35.46539 26.57705 4.49655   1.000 26.24462 ? 73  PHE B CD2 1 
ATOM   1405 C CE1 . PHE B 1 74  ? -32.89764 26.35494 3.50081   1.000 29.61126 ? 73  PHE B CE1 1 
ATOM   1406 C CE2 . PHE B 1 74  ? -34.40105 27.13288 5.19306   1.000 27.51227 ? 73  PHE B CE2 1 
ATOM   1407 C CZ  . PHE B 1 74  ? -33.12246 27.02287 4.69400   1.000 27.20465 ? 73  PHE B CZ  1 
ATOM   1408 N N   . LEU B 1 75  ? -38.09739 24.06904 4.91150   1.000 25.04336 ? 74  LEU B N   1 
ATOM   1409 C CA  . LEU B 1 75  ? -38.33869 24.08831 6.34875   1.000 26.05806 ? 74  LEU B CA  1 
ATOM   1410 C C   . LEU B 1 75  ? -38.34676 22.69943 6.96565   1.000 28.24111 ? 74  LEU B C   1 
ATOM   1411 O O   . LEU B 1 75  ? -38.22345 22.59502 8.19626   1.000 24.47151 ? 74  LEU B O   1 
ATOM   1412 C CB  . LEU B 1 75  ? -39.65748 24.79938 6.66146   1.000 20.26067 ? 74  LEU B CB  1 
ATOM   1413 C CG  . LEU B 1 75  ? -39.61955 26.30187 6.39760   1.000 27.40313 ? 74  LEU B CG  1 
ATOM   1414 C CD1 . LEU B 1 75  ? -41.02112 26.88961 6.38976   1.000 24.89430 ? 74  LEU B CD1 1 
ATOM   1415 C CD2 . LEU B 1 75  ? -38.73430 27.00595 7.42998   1.000 25.33235 ? 74  LEU B CD2 1 
ATOM   1416 N N   . ARG B 1 76  ? -38.48484 21.63970 6.15015   1.000 24.91115 ? 75  ARG B N   1 
ATOM   1417 C CA  . ARG B 1 76  ? -38.40857 20.27932 6.68900   1.000 29.69650 ? 75  ARG B CA  1 
ATOM   1418 C C   . ARG B 1 76  ? -37.12418 20.05570 7.47452   1.000 28.69471 ? 75  ARG B C   1 
ATOM   1419 O O   . ARG B 1 76  ? -37.11205 19.26380 8.42466   1.000 32.09518 ? 75  ARG B O   1 
ATOM   1420 C CB  . ARG B 1 76  ? -38.48870 19.23036 5.57529   1.000 29.59650 ? 75  ARG B CB  1 
ATOM   1421 C CG  . ARG B 1 76  ? -39.87368 19.01387 4.97009   1.000 33.55633 ? 75  ARG B CG  1 
ATOM   1422 C CD  . ARG B 1 76  ? -40.94021 18.68412 6.02587   1.000 34.72499 ? 75  ARG B CD  1 
ATOM   1423 N NE  . ARG B 1 76  ? -40.55419 17.61681 6.94782   1.000 28.59046 ? 75  ARG B NE  1 
ATOM   1424 C CZ  . ARG B 1 76  ? -41.36097 17.13562 7.88518   1.000 32.91877 ? 75  ARG B CZ  1 
ATOM   1425 N NH1 . ARG B 1 76  ? -42.59787 17.58376 8.02710   1.000 27.81896 ? 75  ARG B NH1 1 
ATOM   1426 N NH2 . ARG B 1 76  ? -40.92004 16.17714 8.69590   1.000 37.16766 ? 75  ARG B NH2 1 
ATOM   1427 N N   . ARG B 1 77  ? -36.03463 20.73475 7.09712   1.000 23.39120 ? 76  ARG B N   1 
ATOM   1428 C CA  . ARG B 1 77  ? -34.77041 20.51738 7.78646   1.000 29.49610 ? 76  ARG B CA  1 
ATOM   1429 C C   . ARG B 1 77  ? -34.82143 20.97324 9.24183   1.000 32.17953 ? 76  ARG B C   1 
ATOM   1430 O O   . ARG B 1 77  ? -33.95740 20.57608 10.03288  1.000 33.41838 ? 76  ARG B O   1 
ATOM   1431 C CB  . ARG B 1 77  ? -33.62921 21.21128 7.03652   1.000 28.49751 ? 76  ARG B CB  1 
ATOM   1432 C CG  . ARG B 1 77  ? -33.48810 22.70268 7.29387   1.000 30.23292 ? 76  ARG B CG  1 
ATOM   1433 C CD  . ARG B 1 77  ? -32.60890 23.35338 6.21997   1.000 27.50391 ? 76  ARG B CD  1 
ATOM   1434 N NE  . ARG B 1 77  ? -33.05963 22.97834 4.88789   1.000 27.79950 ? 76  ARG B NE  1 
ATOM   1435 C CZ  . ARG B 1 77  ? -32.30290 22.97999 3.79935   1.000 29.81667 ? 76  ARG B CZ  1 
ATOM   1436 N NH1 . ARG B 1 77  ? -31.04030 23.38263 3.83371   1.000 24.72041 ? 76  ARG B NH1 1 
ATOM   1437 N NH2 . ARG B 1 77  ? -32.82926 22.56924 2.64439   1.000 27.65513 ? 76  ARG B NH2 1 
ATOM   1438 N N   . PHE B 1 78  ? -35.81863 21.77647 9.61550   1.000 29.06668 ? 77  PHE B N   1 
ATOM   1439 C CA  . PHE B 1 78  ? -36.02380 22.19496 10.99640  1.000 31.03666 ? 77  PHE B CA  1 
ATOM   1440 C C   . PHE B 1 78  ? -37.13889 21.41209 11.69252  1.000 32.84195 ? 77  PHE B C   1 
ATOM   1441 O O   . PHE B 1 78  ? -37.50864 21.76248 12.82103  1.000 33.03617 ? 77  PHE B O   1 
ATOM   1442 C CB  . PHE B 1 78  ? -36.34337 23.70027 11.05448  1.000 27.98577 ? 77  PHE B CB  1 
ATOM   1443 C CG  . PHE B 1 78  ? -35.31628 24.58380 10.36034  1.000 31.12499 ? 77  PHE B CG  1 
ATOM   1444 C CD1 . PHE B 1 78  ? -34.06234 24.79005 10.92030  1.000 29.96405 ? 77  PHE B CD1 1 
ATOM   1445 C CD2 . PHE B 1 78  ? -35.61044 25.21422 9.15043   1.000 27.75307 ? 77  PHE B CD2 1 
ATOM   1446 C CE1 . PHE B 1 78  ? -33.11980 25.59809 10.28357  1.000 30.26358 ? 77  PHE B CE1 1 
ATOM   1447 C CE2 . PHE B 1 78  ? -34.66668 26.03030 8.51515   1.000 29.37191 ? 77  PHE B CE2 1 
ATOM   1448 C CZ  . PHE B 1 78  ? -33.42593 26.21411 9.07806   1.000 28.60957 ? 77  PHE B CZ  1 
ATOM   1449 N N   . SER B 1 79  ? -37.68615 20.36177 11.06055  1.000 28.97012 ? 78  SER B N   1 
ATOM   1450 C CA  . SER B 1 79  ? -38.91236 19.75992 11.59021  1.000 30.46706 ? 78  SER B CA  1 
ATOM   1451 C C   . SER B 1 79  ? -38.68049 19.10818 12.95163  1.000 31.92672 ? 78  SER B C   1 
ATOM   1452 O O   . SER B 1 79  ? -39.60690 19.02070 13.76654  1.000 31.33874 ? 78  SER B O   1 
ATOM   1453 C CB  . SER B 1 79  ? -39.50357 18.73178 10.61258  1.000 32.83430 ? 78  SER B CB  1 
ATOM   1454 O OG  . SER B 1 79  ? -38.55412 17.74909 10.21486  1.000 34.04680 ? 78  SER B OG  1 
ATOM   1455 N N   . ALA B 1 80  ? -37.44967 18.65883 13.23104  1.000 32.05544 ? 79  ALA B N   1 
ATOM   1456 C CA  . ALA B 1 80  ? -37.20650 17.95639 14.49017  1.000 34.09501 ? 79  ALA B CA  1 
ATOM   1457 C C   . ALA B 1 80  ? -36.51458 18.81149 15.53960  1.000 35.19020 ? 79  ALA B C   1 
ATOM   1458 O O   . ALA B 1 80  ? -36.30040 18.32931 16.65674  1.000 38.75423 ? 79  ALA B O   1 
ATOM   1459 C CB  . ALA B 1 80  ? -36.37107 16.69066 14.25582  1.000 28.92364 ? 79  ALA B CB  1 
ATOM   1460 N N   . CYS B 1 81  ? -36.15146 20.05462 15.21717  1.000 31.14315 ? 80  CYS B N   1 
ATOM   1461 C CA  . CYS B 1 81  ? -35.39782 20.88626 16.14041  1.000 30.73334 ? 80  CYS B CA  1 
ATOM   1462 C C   . CYS B 1 81  ? -35.86215 22.33611 16.11979  1.000 33.84661 ? 80  CYS B C   1 
ATOM   1463 O O   . CYS B 1 81  ? -35.01317 23.24773 16.10554  1.000 37.12226 ? 80  CYS B O   1 
ATOM   1464 C CB  . CYS B 1 81  ? -33.91594 20.80084 15.79511  1.000 29.34115 ? 80  CYS B CB  1 
ATOM   1465 S SG  . CYS B 1 81  ? -33.60172 21.50962 14.15235  1.000 35.36735 ? 80  CYS B SG  1 
ATOM   1466 N N   . SER B 1 82  ? -37.18562 22.55596 16.10883  1.000 31.89214 ? 81  SER B N   1 
ATOM   1467 C CA  . SER B 1 82  ? -37.81489 23.87167 16.03424  1.000 33.39791 ? 81  SER B CA  1 
ATOM   1468 C C   . SER B 1 82  ? -39.25839 23.76011 16.51508  1.000 31.02741 ? 81  SER B C   1 
ATOM   1469 O O   . SER B 1 82  ? -39.77945 22.66780 16.76165  1.000 36.69633 ? 81  SER B O   1 
ATOM   1470 C CB  . SER B 1 82  ? -37.78090 24.45581 14.60254  1.000 29.94685 ? 81  SER B CB  1 
ATOM   1471 O OG  . SER B 1 82  ? -38.81556 23.90168 13.79131  1.000 33.66729 ? 81  SER B OG  1 
ATOM   1472 N N   . VAL B 1 83  ? -39.91585 24.90446 16.65603  1.000 30.03458 ? 82  VAL B N   1 
ATOM   1473 C CA  . VAL B 1 83  ? -41.34617 24.92735 16.93660  1.000 28.56077 ? 82  VAL B CA  1 
ATOM   1474 C C   . VAL B 1 83  ? -42.02952 25.91099 15.99985  1.000 30.42990 ? 82  VAL B C   1 
ATOM   1475 O O   . VAL B 1 83  ? -41.63463 27.07480 15.88258  1.000 31.15166 ? 82  VAL B O   1 
ATOM   1476 C CB  . VAL B 1 83  ? -41.67470 25.26737 18.40679  1.000 35.34121 ? 82  VAL B CB  1 
ATOM   1477 C CG1 . VAL B 1 83  ? -43.16819 25.23040 18.59181  1.000 34.27429 ? 82  VAL B CG1 1 
ATOM   1478 C CG2 . VAL B 1 83  ? -41.02952 24.24681 19.36614  1.000 30.62374 ? 82  VAL B CG2 1 
ATOM   1479 N N   . GLY B 1 84  ? -43.05339 25.42673 15.30693  1.000 27.84147 ? 83  GLY B N   1 
ATOM   1480 C CA  . GLY B 1 84  ? -43.89974 26.32057 14.55106  1.000 26.82475 ? 83  GLY B CA  1 
ATOM   1481 C C   . GLY B 1 84  ? -43.60678 26.40329 13.06767  1.000 28.72328 ? 83  GLY B C   1 
ATOM   1482 O O   . GLY B 1 84  ? -44.11754 27.30549 12.39642  1.000 27.26622 ? 83  GLY B O   1 
ATOM   1483 N N   . PHE B 1 85  ? -42.81881 25.46971 12.52672  1.000 27.36668 ? 84  PHE B N   1 
ATOM   1484 C CA  . PHE B 1 85  ? -42.42848 25.55599 11.12322  1.000 29.00697 ? 84  PHE B CA  1 
ATOM   1485 C C   . PHE B 1 85  ? -43.61861 25.38137 10.17885  1.000 27.65717 ? 84  PHE B C   1 
ATOM   1486 O O   . PHE B 1 85  ? -43.62366 25.96176 9.08940   1.000 28.14295 ? 84  PHE B O   1 
ATOM   1487 C CB  . PHE B 1 85  ? -41.33639 24.52949 10.81762  1.000 25.77919 ? 84  PHE B CB  1 
ATOM   1488 C CG  . PHE B 1 85  ? -41.83945 23.11749 10.65865  1.000 29.22202 ? 84  PHE B CG  1 
ATOM   1489 C CD1 . PHE B 1 85  ? -42.12361 22.33405 11.76372  1.000 30.11941 ? 84  PHE B CD1 1 
ATOM   1490 C CD2 . PHE B 1 85  ? -42.00002 22.56491 9.39706   1.000 31.29416 ? 84  PHE B CD2 1 
ATOM   1491 C CE1 . PHE B 1 85  ? -42.57993 21.02449 11.61475  1.000 28.79414 ? 84  PHE B CE1 1 
ATOM   1492 C CE2 . PHE B 1 85  ? -42.45872 21.25715 9.23776   1.000 30.23327 ? 84  PHE B CE2 1 
ATOM   1493 C CZ  . PHE B 1 85  ? -42.74809 20.49072 10.34952  1.000 29.73071 ? 84  PHE B CZ  1 
ATOM   1494 N N   . GLU B 1 86  ? -44.64176 24.62249 10.58768  1.000 28.08984 ? 85  GLU B N   1 
ATOM   1495 C CA  . GLU B 1 86  ? -45.80268 24.39569 9.72889   1.000 29.55208 ? 85  GLU B CA  1 
ATOM   1496 C C   . GLU B 1 86  ? -46.50503 25.69148 9.34549   1.000 27.91145 ? 85  GLU B C   1 
ATOM   1497 O O   . GLU B 1 86  ? -47.17232 25.74826 8.30576   1.000 28.82624 ? 85  GLU B O   1 
ATOM   1498 C CB  . GLU B 1 86  ? -46.79647 23.46206 10.42141  1.000 27.89212 ? 85  GLU B CB  1 
ATOM   1499 C CG  . GLU B 1 86  ? -46.26195 22.06398 10.67455  1.000 29.56736 ? 85  GLU B CG  1 
ATOM   1500 C CD  . GLU B 1 86  ? -45.77307 21.89264 12.10299  1.000 34.90641 ? 85  GLU B CD  1 
ATOM   1501 O OE1 . GLU B 1 86  ? -45.38108 22.91029 12.71591  1.000 33.35405 ? 85  GLU B OE1 1 
ATOM   1502 O OE2 . GLU B 1 86  ? -45.78036 20.75175 12.60987  1.000 30.42622 ? 85  GLU B OE2 1 
ATOM   1503 N N   . GLU B 1 87  ? -46.38414 26.73016 10.17060  1.000 28.19676 ? 86  GLU B N   1 
ATOM   1504 C CA  . GLU B 1 87  ? -47.09075 27.98627 9.96915   1.000 26.62138 ? 86  GLU B CA  1 
ATOM   1505 C C   . GLU B 1 87  ? -46.22629 29.05940 9.33600   1.000 25.68952 ? 86  GLU B C   1 
ATOM   1506 O O   . GLU B 1 87  ? -46.73134 30.15464 9.05571   1.000 24.47263 ? 86  GLU B O   1 
ATOM   1507 C CB  . GLU B 1 87  ? -47.61227 28.53141 11.30921  1.000 29.46259 ? 86  GLU B CB  1 
ATOM   1508 C CG  . GLU B 1 87  ? -48.63412 27.67261 12.02495  1.000 30.88772 ? 86  GLU B CG  1 
ATOM   1509 C CD  . GLU B 1 87  ? -49.98272 27.66982 11.33231  1.000 40.20544 ? 86  GLU B CD  1 
ATOM   1510 O OE1 . GLU B 1 87  ? -50.20776 28.52529 10.43568  1.000 35.15900 ? 86  GLU B OE1 1 
ATOM   1511 O OE2 . GLU B 1 87  ? -50.83623 26.84242 11.72860  1.000 40.04161 ? 86  GLU B OE2 1 
ATOM   1512 N N   . ILE B 1 88  ? -44.94114 28.79390 9.13598   1.000 26.03408 ? 87  ILE B N   1 
ATOM   1513 C CA  . ILE B 1 88  ? -44.00560 29.85302 8.76067   1.000 25.60947 ? 87  ILE B CA  1 
ATOM   1514 C C   . ILE B 1 88  ? -44.27972 30.31038 7.33014   1.000 25.09508 ? 87  ILE B C   1 
ATOM   1515 O O   . ILE B 1 88  ? -44.29106 31.52766 7.09435   1.000 24.93941 ? 87  ILE B O   1 
ATOM   1516 C CB  . ILE B 1 88  ? -42.54746 29.40899 8.97974   1.000 23.81227 ? 87  ILE B CB  1 
ATOM   1517 C CG1 . ILE B 1 88  ? -42.20691 29.47422 10.46416  1.000 25.46464 ? 87  ILE B CG1 1 
ATOM   1518 C CG2 . ILE B 1 88  ? -41.56470 30.29044 8.21689   1.000 23.28408 ? 87  ILE B CG2 1 
ATOM   1519 C CD1 . ILE B 1 88  ? -42.24313 30.89720 11.01823  1.000 24.56822 ? 87  ILE B CD1 1 
ATOM   1520 N N   . PRO B 1 89  ? -44.54186 29.42448 6.35136   1.000 23.61231 ? 88  PRO B N   1 
ATOM   1521 C CA  . PRO B 1 89  ? -44.90744 29.94601 5.02068   1.000 23.72600 ? 88  PRO B CA  1 
ATOM   1522 C C   . PRO B 1 89  ? -46.11565 30.86134 5.05567   1.000 23.77609 ? 88  PRO B C   1 
ATOM   1523 O O   . PRO B 1 89  ? -46.11300 31.90835 4.39680   1.000 23.96000 ? 88  PRO B O   1 
ATOM   1524 C CB  . PRO B 1 89  ? -45.17281 28.67244 4.20634   1.000 23.98890 ? 88  PRO B CB  1 
ATOM   1525 C CG  . PRO B 1 89  ? -44.26157 27.66756 4.82494   1.000 25.25022 ? 88  PRO B CG  1 
ATOM   1526 C CD  . PRO B 1 89  ? -44.42488 27.95311 6.31357   1.000 22.25628 ? 88  PRO B CD  1 
ATOM   1527 N N   . THR B 1 90  ? -47.14660 30.49944 5.82174   1.000 24.77341 ? 89  THR B N   1 
ATOM   1528 C CA  . THR B 1 90  ? -48.28930 31.38993 6.01489   1.000 23.60609 ? 89  THR B CA  1 
ATOM   1529 C C   . THR B 1 90  ? -47.86477 32.72091 6.62963   1.000 26.07338 ? 89  THR B C   1 
ATOM   1530 O O   . THR B 1 90  ? -48.37269 33.78571 6.25182   1.000 23.04710 ? 89  THR B O   1 
ATOM   1531 C CB  . THR B 1 90  ? -49.32049 30.70933 6.90687   1.000 27.59245 ? 89  THR B CB  1 
ATOM   1532 O OG1 . THR B 1 90  ? -49.74824 29.49129 6.28628   1.000 24.46258 ? 89  THR B OG1 1 
ATOM   1533 C CG2 . THR B 1 90  ? -50.51547 31.63185 7.16123   1.000 28.14636 ? 89  THR B CG2 1 
ATOM   1534 N N   . ALA B 1 91  ? -46.94288 32.68190 7.59462   1.000 26.10939 ? 90  ALA B N   1 
ATOM   1535 C CA  . ALA B 1 91  ? -46.52521 33.91956 8.23895   1.000 26.00288 ? 90  ALA B CA  1 
ATOM   1536 C C   . ALA B 1 91  ? -45.81711 34.82876 7.24354   1.000 25.53590 ? 90  ALA B C   1 
ATOM   1537 O O   . ALA B 1 91  ? -46.03832 36.04688 7.23555   1.000 25.84927 ? 90  ALA B O   1 
ATOM   1538 C CB  . ALA B 1 91  ? -45.63073 33.60786 9.44645   1.000 22.45185 ? 90  ALA B CB  1 
ATOM   1539 N N   . LEU B 1 92  ? -44.97853 34.25382 6.37787   1.000 21.92099 ? 91  LEU B N   1 
ATOM   1540 C CA  . LEU B 1 92  ? -44.28068 35.07028 5.38900   1.000 24.91235 ? 91  LEU B CA  1 
ATOM   1541 C C   . LEU B 1 92  ? -45.25745 35.69146 4.39380   1.000 26.29354 ? 91  LEU B C   1 
ATOM   1542 O O   . LEU B 1 92  ? -45.08948 36.85109 3.99007   1.000 25.11436 ? 91  LEU B O   1 
ATOM   1543 C CB  . LEU B 1 92  ? -43.21956 34.23782 4.66675   1.000 27.18673 ? 91  LEU B CB  1 
ATOM   1544 C CG  . LEU B 1 92  ? -41.81278 34.53255 5.20256   1.000 27.29328 ? 91  LEU B CG  1 
ATOM   1545 C CD1 . LEU B 1 92  ? -41.62768 33.89629 6.58091   1.000 26.43122 ? 91  LEU B CD1 1 
ATOM   1546 C CD2 . LEU B 1 92  ? -40.72884 34.08760 4.24137   1.000 26.66507 ? 91  LEU B CD2 1 
ATOM   1547 N N   . GLN B 1 93  ? -46.30105 34.95291 4.00653   1.000 26.49512 ? 92  GLN B N   1 
ATOM   1548 C CA  . GLN B 1 93  ? -47.31731 35.53553 3.13037   1.000 29.27128 ? 92  GLN B CA  1 
ATOM   1549 C C   . GLN B 1 93  ? -47.94722 36.76742 3.77347   1.000 27.27149 ? 92  GLN B C   1 
ATOM   1550 O O   . GLN B 1 93  ? -48.10766 37.80723 3.12485   1.000 23.92335 ? 92  GLN B O   1 
ATOM   1551 C CB  . GLN B 1 93  ? -48.39756 34.50541 2.79069   1.000 26.13759 ? 92  GLN B CB  1 
ATOM   1552 C CG  . GLN B 1 93  ? -47.92110 33.34883 1.93462   1.000 34.58674 ? 92  GLN B CG  1 
ATOM   1553 C CD  . GLN B 1 93  ? -47.76653 33.72560 0.47172   1.000 44.43364 ? 92  GLN B CD  1 
ATOM   1554 O OE1 . GLN B 1 93  ? -48.54706 34.51623 -0.06435  1.000 45.67007 ? 92  GLN B OE1 1 
ATOM   1555 N NE2 . GLN B 1 93  ? -46.74532 33.16795 -0.18117  1.000 42.60619 ? 92  GLN B NE2 1 
ATOM   1556 N N   . ARG B 1 94  ? -48.30970 36.66184 5.05762   1.000 25.14898 ? 93  ARG B N   1 
ATOM   1557 C CA  . ARG B 1 94  ? -48.90723 37.79414 5.76336   1.000 25.02587 ? 93  ARG B CA  1 
ATOM   1558 C C   . ARG B 1 94  ? -47.92930 38.95961 5.86570   1.000 24.20375 ? 93  ARG B C   1 
ATOM   1559 O O   . ARG B 1 94  ? -48.29107 40.11464 5.60093   1.000 24.39447 ? 93  ARG B O   1 
ATOM   1560 C CB  . ARG B 1 94  ? -49.37095 37.34042 7.15059   1.000 25.88838 ? 93  ARG B CB  1 
ATOM   1561 C CG  . ARG B 1 94  ? -50.21561 38.34122 7.93420   1.000 27.05944 ? 93  ARG B CG  1 
ATOM   1562 C CD  . ARG B 1 94  ? -50.46539 37.83976 9.37400   1.000 28.06737 ? 93  ARG B CD  1 
ATOM   1563 N NE  . ARG B 1 94  ? -49.23961 37.49895 10.09449  1.000 29.84013 ? 93  ARG B NE  1 
ATOM   1564 C CZ  . ARG B 1 94  ? -48.88446 36.27437 10.47519  1.000 32.69760 ? 93  ARG B CZ  1 
ATOM   1565 N NH1 . ARG B 1 94  ? -49.62140 35.21228 10.18567  1.000 29.68065 ? 93  ARG B NH1 1 
ATOM   1566 N NH2 . ARG B 1 94  ? -47.75688 36.10940 11.16482  1.000 34.23433 ? 93  ARG B NH2 1 
ATOM   1567 N N   . ILE B 1 95  ? -46.67762 38.67232 6.22749   1.000 25.83624 ? 94  ILE B N   1 
ATOM   1568 C CA  . ILE B 1 95  ? -45.68753 39.73208 6.41682   1.000 26.10718 ? 94  ILE B CA  1 
ATOM   1569 C C   . ILE B 1 95  ? -45.42994 40.44877 5.09619   1.000 26.13376 ? 94  ILE B C   1 
ATOM   1570 O O   . ILE B 1 95  ? -45.40480 41.68559 5.03289   1.000 24.68719 ? 94  ILE B O   1 
ATOM   1571 C CB  . ILE B 1 95  ? -44.39612 39.14747 7.02203   1.000 23.94838 ? 94  ILE B CB  1 
ATOM   1572 C CG1 . ILE B 1 95  ? -44.61509 38.77815 8.49267   1.000 27.25256 ? 94  ILE B CG1 1 
ATOM   1573 C CG2 . ILE B 1 95  ? -43.23540 40.11466 6.90909   1.000 26.43392 ? 94  ILE B CG2 1 
ATOM   1574 C CD1 . ILE B 1 95  ? -43.65765 37.70597 8.99137   1.000 26.02897 ? 94  ILE B CD1 1 
ATOM   1575 N N   . ARG B 1 96  ? -45.25166 39.67396 4.01763   1.000 22.79203 ? 95  ARG B N   1 
ATOM   1576 C CA  . ARG B 1 96  ? -45.11496 40.24267 2.67774   1.000 23.26243 ? 95  ARG B CA  1 
ATOM   1577 C C   . ARG B 1 96  ? -46.31056 41.11951 2.32083   1.000 26.72421 ? 95  ARG B C   1 
ATOM   1578 O O   . ARG B 1 96  ? -46.16025 42.20512 1.74753   1.000 28.50298 ? 95  ARG B O   1 
ATOM   1579 C CB  . ARG B 1 96  ? -44.97448 39.11372 1.65422   1.000 22.10743 ? 95  ARG B CB  1 
ATOM   1580 C CG  . ARG B 1 96  ? -43.57030 38.55583 1.52878   1.000 27.68287 ? 95  ARG B CG  1 
ATOM   1581 C CD  . ARG B 1 96  ? -43.59335 37.13515 0.97407   1.000 25.80828 ? 95  ARG B CD  1 
ATOM   1582 N NE  . ARG B 1 96  ? -43.92410 37.13630 -0.44586  1.000 26.72484 ? 95  ARG B NE  1 
ATOM   1583 C CZ  . ARG B 1 96  ? -44.11368 36.03873 -1.16463  1.000 33.14303 ? 95  ARG B CZ  1 
ATOM   1584 N NH1 . ARG B 1 96  ? -43.95015 34.83502 -0.64094  1.000 33.64927 ? 95  ARG B NH1 1 
ATOM   1585 N NH2 . ARG B 1 96  ? -44.47307 36.15054 -2.44003  1.000 31.37547 ? 95  ARG B NH2 1 
ATOM   1586 N N   . SER B 1 97  ? -47.51469 40.63990 2.61549   1.000 24.43719 ? 96  SER B N   1 
ATOM   1587 C CA  . SER B 1 97  ? -48.71021 41.41903 2.32844   1.000 25.37928 ? 96  SER B CA  1 
ATOM   1588 C C   . SER B 1 97  ? -48.73652 42.71898 3.13525   1.000 27.61840 ? 96  SER B C   1 
ATOM   1589 O O   . SER B 1 97  ? -49.10481 43.77969 2.61023   1.000 24.46326 ? 96  SER B O   1 
ATOM   1590 C CB  . SER B 1 97  ? -49.93659 40.55059 2.61012   1.000 30.69632 ? 96  SER B CB  1 
ATOM   1591 O OG  . SER B 1 97  ? -51.04060 41.33081 3.02264   1.000 40.10991 ? 96  SER B OG  1 
ATOM   1592 N N   . VAL B 1 98  ? -48.32198 42.66140 4.40738   1.000 26.75704 ? 97  VAL B N   1 
ATOM   1593 C CA  . VAL B 1 98  ? -48.37866 43.83938 5.27227   1.000 23.12497 ? 97  VAL B CA  1 
ATOM   1594 C C   . VAL B 1 98  ? -47.29686 44.83756 4.88221   1.000 26.06680 ? 97  VAL B C   1 
ATOM   1595 O O   . VAL B 1 98  ? -47.56195 46.03729 4.72916   1.000 24.28503 ? 97  VAL B O   1 
ATOM   1596 C CB  . VAL B 1 98  ? -48.24946 43.42852 6.75232   1.000 26.11529 ? 97  VAL B CB  1 
ATOM   1597 C CG1 . VAL B 1 98  ? -47.98577 44.65757 7.62658   1.000 24.79300 ? 97  VAL B CG1 1 
ATOM   1598 C CG2 . VAL B 1 98  ? -49.49977 42.68609 7.21458   1.000 23.50189 ? 97  VAL B CG2 1 
ATOM   1599 N N   . TYR B 1 99  ? -46.05565 44.35958 4.72000   1.000 24.07026 ? 98  TYR B N   1 
ATOM   1600 C CA  . TYR B 1 99  ? -44.97092 45.25854 4.34532   1.000 24.44605 ? 98  TYR B CA  1 
ATOM   1601 C C   . TYR B 1 99  ? -45.19122 45.85264 2.95732   1.000 26.88937 ? 98  TYR B C   1 
ATOM   1602 O O   . TYR B 1 99  ? -44.94437 47.04920 2.74468   1.000 24.58679 ? 98  TYR B O   1 
ATOM   1603 C CB  . TYR B 1 99  ? -43.62863 44.52740 4.40211   1.000 27.78370 ? 98  TYR B CB  1 
ATOM   1604 C CG  . TYR B 1 99  ? -42.43780 45.44198 4.18527   1.000 28.50532 ? 98  TYR B CG  1 
ATOM   1605 C CD1 . TYR B 1 99  ? -42.11342 46.43707 5.10744   1.000 31.54330 ? 98  TYR B CD1 1 
ATOM   1606 C CD2 . TYR B 1 99  ? -41.65130 45.32436 3.05021   1.000 27.88421 ? 98  TYR B CD2 1 
ATOM   1607 C CE1 . TYR B 1 99  ? -41.01778 47.28187 4.90216   1.000 32.25562 ? 98  TYR B CE1 1 
ATOM   1608 C CE2 . TYR B 1 99  ? -40.56422 46.15558 2.83727   1.000 27.92371 ? 98  TYR B CE2 1 
ATOM   1609 C CZ  . TYR B 1 99  ? -40.25001 47.13057 3.75886   1.000 31.21835 ? 98  TYR B CZ  1 
ATOM   1610 O OH  . TYR B 1 99  ? -39.16037 47.94280 3.51976   1.000 32.67212 ? 98  TYR B OH  1 
ATOM   1611 N N   . THR B 1 100 ? -45.63626 45.03601 1.99182   1.000 24.79700 ? 99  THR B N   1 
ATOM   1612 C CA  . THR B 1 100 ? -45.89998 45.57595 0.65869   1.000 27.34298 ? 99  THR B CA  1 
ATOM   1613 C C   . THR B 1 100 ? -46.92174 46.69951 0.71962   1.000 26.36716 ? 99  THR B C   1 
ATOM   1614 O O   . THR B 1 100 ? -46.76819 47.72666 0.04589   1.000 25.85966 ? 99  THR B O   1 
ATOM   1615 C CB  . THR B 1 100 ? -46.39343 44.48653 -0.29645  1.000 25.19669 ? 99  THR B CB  1 
ATOM   1616 O OG1 . THR B 1 100 ? -45.35681 43.52280 -0.52098  1.000 27.23236 ? 99  THR B OG1 1 
ATOM   1617 C CG2 . THR B 1 100 ? -46.80966 45.10101 -1.62970  1.000 24.84717 ? 99  THR B CG2 1 
ATOM   1618 N N   . ALA B 1 101 ? -47.97173 46.52724 1.52741   1.000 24.67954 ? 100 ALA B N   1 
ATOM   1619 C CA  . ALA B 1 101 ? -49.01718 47.54568 1.57970   1.000 26.36618 ? 100 ALA B CA  1 
ATOM   1620 C C   . ALA B 1 101 ? -48.50695 48.80829 2.26075   1.000 27.02381 ? 100 ALA B C   1 
ATOM   1621 O O   . ALA B 1 101 ? -48.86209 49.92829 1.86416   1.000 26.15167 ? 100 ALA B O   1 
ATOM   1622 C CB  . ALA B 1 101 ? -50.25729 47.00182 2.29301   1.000 23.21004 ? 100 ALA B CB  1 
ATOM   1623 N N   . LYS B 1 102 ? -47.66128 48.64517 3.27897   1.000 27.74949 ? 101 LYS B N   1 
ATOM   1624 C CA  . LYS B 1 102 ? -47.04876 49.80012 3.92793   1.000 28.88894 ? 101 LYS B CA  1 
ATOM   1625 C C   . LYS B 1 102 ? -46.23638 50.61871 2.93011   1.000 29.23302 ? 101 LYS B C   1 
ATOM   1626 O O   . LYS B 1 102 ? -46.34708 51.85017 2.87062   1.000 27.73372 ? 101 LYS B O   1 
ATOM   1627 C CB  . LYS B 1 102 ? -46.17635 49.32693 5.08836   1.000 28.52931 ? 101 LYS B CB  1 
ATOM   1628 C CG  . LYS B 1 102 ? -45.49980 50.44776 5.86473   1.000 30.92214 ? 101 LYS B CG  1 
ATOM   1629 C CD  . LYS B 1 102 ? -44.77152 49.88840 7.08663   1.000 31.73587 ? 101 LYS B CD  1 
ATOM   1630 C CE  . LYS B 1 102 ? -44.34786 51.00832 8.04472   1.000 35.65107 ? 101 LYS B CE  1 
ATOM   1631 N NZ  . LYS B 1 102 ? -43.68269 50.47859 9.27172   1.000 31.05478 ? 101 LYS B NZ  1 
ATOM   1632 N N   . LEU B 1 103 ? -45.42366 49.94492 2.11967   1.000 26.58617 ? 102 LEU B N   1 
ATOM   1633 C CA  . LEU B 1 103 ? -44.61641 50.65285 1.13366   1.000 27.78640 ? 102 LEU B CA  1 
ATOM   1634 C C   . LEU B 1 103 ? -45.48458 51.31730 0.07381   1.000 29.71792 ? 102 LEU B C   1 
ATOM   1635 O O   . LEU B 1 103 ? -45.20960 52.45002 -0.33789  1.000 30.86883 ? 102 LEU B O   1 
ATOM   1636 C CB  . LEU B 1 103 ? -43.62316 49.68784 0.47938   1.000 28.56475 ? 102 LEU B CB  1 
ATOM   1637 C CG  . LEU B 1 103 ? -42.43578 49.19249 1.31288   1.000 26.84969 ? 102 LEU B CG  1 
ATOM   1638 C CD1 . LEU B 1 103 ? -41.36304 48.59501 0.42751   1.000 25.16541 ? 102 LEU B CD1 1 
ATOM   1639 C CD2 . LEU B 1 103 ? -41.85846 50.32626 2.13510   1.000 31.11886 ? 102 LEU B CD2 1 
ATOM   1640 N N   . LEU B 1 104 ? -46.52779 50.62491 -0.39776  1.000 27.12161 ? 103 LEU B N   1 
ATOM   1641 C CA  . LEU B 1 104 ? -47.32091 51.15441 -1.49778  1.000 29.84656 ? 103 LEU B CA  1 
ATOM   1642 C C   . LEU B 1 104 ? -48.30088 52.22848 -1.07005  1.000 28.19457 ? 103 LEU B C   1 
ATOM   1643 O O   . LEU B 1 104 ? -48.70291 53.03809 -1.90888  1.000 35.57842 ? 103 LEU B O   1 
ATOM   1644 C CB  . LEU B 1 104 ? -48.10507 50.03772 -2.20046  1.000 26.56956 ? 103 LEU B CB  1 
ATOM   1645 C CG  . LEU B 1 104 ? -47.27282 48.94890 -2.87647  1.000 29.71656 ? 103 LEU B CG  1 
ATOM   1646 C CD1 . LEU B 1 104 ? -48.16866 47.90332 -3.51934  1.000 27.30479 ? 103 LEU B CD1 1 
ATOM   1647 C CD2 . LEU B 1 104 ? -46.33349 49.57824 -3.89799  1.000 24.21678 ? 103 LEU B CD2 1 
ATOM   1648 N N   . GLU B 1 105 ? -48.70095 52.24431 0.19434   1.000 32.23932 ? 104 GLU B N   1 
ATOM   1649 C CA  . GLU B 1 105 ? -49.79451 53.08765 0.65718   1.000 34.97059 ? 104 GLU B CA  1 
ATOM   1650 C C   . GLU B 1 105 ? -49.60136 54.56099 0.32054   1.000 39.69749 ? 104 GLU B C   1 
ATOM   1651 O O   . GLU B 1 105 ? -48.50736 55.08573 0.47347   1.000 37.15585 ? 104 GLU B O   1 
ATOM   1652 C CB  . GLU B 1 105 ? -49.96288 52.93264 2.15958   1.000 35.58097 ? 104 GLU B CB  1 
ATOM   1653 C CG  . GLU B 1 105 ? -51.03686 53.81748 2.73782   1.000 38.24435 ? 104 GLU B CG  1 
ATOM   1654 C CD  . GLU B 1 105 ? -50.45326 54.95296 3.52457   1.000 41.91919 ? 104 GLU B CD  1 
ATOM   1655 O OE1 . GLU B 1 105 ? -49.44012 54.72522 4.22009   1.000 46.33471 ? 104 GLU B OE1 1 
ATOM   1656 O OE2 . GLU B 1 105 ? -51.01361 56.06833 3.45732   1.000 49.16541 ? 104 GLU B OE2 1 
ATOM   1657 N N   . GLY C 1 1   ? -40.36903 49.59820 17.88662  1.000 57.01738 ? 0   GLY C N   1 
ATOM   1658 C CA  . GLY C 1 1   ? -38.96948 49.86212 18.19371  1.000 52.61729 ? 0   GLY C CA  1 
ATOM   1659 C C   . GLY C 1 1   ? -38.76249 50.51799 19.54729  1.000 57.51277 ? 0   GLY C C   1 
ATOM   1660 O O   . GLY C 1 1   ? -39.61000 51.28500 20.00907  1.000 64.67073 ? 0   GLY C O   1 
ATOM   1661 N N   . MET C 1 2   ? -37.62809 50.22698 20.17745  1.000 50.40524 ? 1   MET C N   1 
ATOM   1662 C CA  . MET C 1 2   ? -37.37711 50.70618 21.52703  1.000 51.44160 ? 1   MET C CA  1 
ATOM   1663 C C   . MET C 1 2   ? -37.12176 52.21131 21.51494  1.000 50.63879 ? 1   MET C C   1 
ATOM   1664 O O   . MET C 1 2   ? -36.32787 52.71942 20.71222  1.000 48.76498 ? 1   MET C O   1 
ATOM   1665 C CB  . MET C 1 2   ? -36.19128 49.95871 22.13184  1.000 50.32073 ? 1   MET C CB  1 
ATOM   1666 C CG  . MET C 1 2   ? -35.77519 50.44021 23.50871  1.000 50.63073 ? 1   MET C CG  1 
ATOM   1667 S SD  . MET C 1 2   ? -34.54978 49.34906 24.24417  1.000 77.56073 ? 1   MET C SD  1 
ATOM   1668 C CE  . MET C 1 2   ? -35.32829 47.76334 24.00782  1.000 56.84073 ? 1   MET C CE  1 
ATOM   1669 N N   . ILE C 1 3   ? -37.79909 52.91920 22.41112  1.000 44.91518 ? 2   ILE C N   1 
ATOM   1670 C CA  . ILE C 1 3   ? -37.61577 54.35455 22.56672  1.000 46.10563 ? 2   ILE C CA  1 
ATOM   1671 C C   . ILE C 1 3   ? -36.31303 54.62815 23.31192  1.000 46.92115 ? 2   ILE C C   1 
ATOM   1672 O O   . ILE C 1 3   ? -35.93754 53.88887 24.22746  1.000 43.36841 ? 2   ILE C O   1 
ATOM   1673 C CB  . ILE C 1 3   ? -38.82664 54.95004 23.30125  1.000 47.03206 ? 2   ILE C CB  1 
ATOM   1674 C CG1 . ILE C 1 3   ? -40.08362 54.78519 22.44153  1.000 51.08360 ? 2   ILE C CG1 1 
ATOM   1675 C CG2 . ILE C 1 3   ? -38.57151 56.39990 23.66697  1.000 50.54136 ? 2   ILE C CG2 1 
ATOM   1676 C CD1 . ILE C 1 3   ? -39.96620 55.43532 21.06973  1.000 51.77461 ? 2   ILE C CD1 1 
ATOM   1677 N N   . GLY C 1 4   ? -35.61696 55.69873 22.92671  1.000 43.95426 ? 3   GLY C N   1 
ATOM   1678 C CA  . GLY C 1 4   ? -34.35892 56.08877 23.54944  1.000 44.89075 ? 3   GLY C CA  1 
ATOM   1679 C C   . GLY C 1 4   ? -33.26197 56.47285 22.57025  1.000 45.47119 ? 3   GLY C C   1 
ATOM   1680 O O   . GLY C 1 4   ? -33.44004 56.34876 21.35698  1.000 42.49600 ? 3   GLY C O   1 
ATOM   1681 N N   . SER C 1 5   ? -32.12430 56.93676 23.08291  1.000 44.15233 ? 4   SER C N   1 
ATOM   1682 C CA  . SER C 1 5   ? -30.95915 57.18944 22.25028  1.000 47.36532 ? 4   SER C CA  1 
ATOM   1683 C C   . SER C 1 5   ? -30.34684 55.86976 21.77870  1.000 50.60018 ? 4   SER C C   1 
ATOM   1684 O O   . SER C 1 5   ? -30.58370 54.80019 22.35264  1.000 45.99585 ? 4   SER C O   1 
ATOM   1685 C CB  . SER C 1 5   ? -29.92239 58.02154 23.01418  1.000 44.92426 ? 4   SER C CB  1 
ATOM   1686 O OG  . SER C 1 5   ? -29.10050 57.20424 23.83745  1.000 48.11682 ? 4   SER C OG  1 
ATOM   1687 N N   . GLU C 1 6   ? -29.55385 55.95966 20.70419  1.000 49.44528 ? 5   GLU C N   1 
ATOM   1688 C CA  . GLU C 1 6   ? -28.84251 54.78501 20.20230  1.000 49.98769 ? 5   GLU C CA  1 
ATOM   1689 C C   . GLU C 1 6   ? -27.98978 54.14832 21.29875  1.000 49.35113 ? 5   GLU C C   1 
ATOM   1690 O O   . GLU C 1 6   ? -27.91778 52.91487 21.40388  1.000 49.04452 ? 5   GLU C O   1 
ATOM   1691 C CB  . GLU C 1 6   ? -27.96763 55.15606 18.99863  1.000 51.57712 ? 5   GLU C CB  1 
ATOM   1692 C CG  . GLU C 1 6   ? -26.70857 54.27437 18.90916  1.000 59.97833 ? 5   GLU C CG  1 
ATOM   1693 C CD  . GLU C 1 6   ? -25.68469 54.77774 17.90278  1.000 68.17972 ? 5   GLU C CD  1 
ATOM   1694 O OE1 . GLU C 1 6   ? -26.06298 54.99158 16.72138  1.000 69.49744 ? 5   GLU C OE1 1 
ATOM   1695 O OE2 . GLU C 1 6   ? -24.50450 54.95220 18.29873  1.000 60.94859 ? 5   GLU C OE2 1 
ATOM   1696 N N   . LYS C 1 7   ? -27.31189 54.97710 22.09862  1.000 43.81557 ? 6   LYS C N   1 
ATOM   1697 C CA  . LYS C 1 7   ? -26.57320 54.49812 23.26201  1.000 45.81139 ? 6   LYS C CA  1 
ATOM   1698 C C   . LYS C 1 7   ? -27.47964 53.69569 24.18923  1.000 50.72760 ? 6   LYS C C   1 
ATOM   1699 O O   . LYS C 1 7   ? -27.16063 52.56275 24.57086  1.000 47.54397 ? 6   LYS C O   1 
ATOM   1700 C CB  . LYS C 1 7   ? -25.97711 55.68759 24.01735  1.000 47.67243 ? 6   LYS C CB  1 
ATOM   1701 C CG  . LYS C 1 7   ? -24.71619 55.41406 24.83205  1.000 52.69535 ? 6   LYS C CG  1 
ATOM   1702 C CD  . LYS C 1 7   ? -23.44295 55.57413 24.01987  1.000 48.06008 ? 6   LYS C CD  1 
ATOM   1703 C CE  . LYS C 1 7   ? -22.35712 56.24377 24.87880  1.000 52.33988 ? 6   LYS C CE  1 
ATOM   1704 N NZ  . LYS C 1 7   ? -21.45185 57.15844 24.09090  1.000 47.13000 ? 6   LYS C NZ  1 
ATOM   1705 N N   . GLN C 1 8   ? -28.60316 54.29474 24.60092  1.000 44.16795 ? 7   GLN C N   1 
ATOM   1706 C CA  . GLN C 1 8   ? -29.45216 53.61774 25.57276  1.000 45.38479 ? 7   GLN C CA  1 
ATOM   1707 C C   . GLN C 1 8   ? -30.13271 52.39657 24.96705  1.000 40.17648 ? 7   GLN C C   1 
ATOM   1708 O O   . GLN C 1 8   ? -30.26603 51.37324 25.64525  1.000 44.14793 ? 7   GLN C O   1 
ATOM   1709 C CB  . GLN C 1 8   ? -30.48108 54.58726 26.16240  1.000 45.07555 ? 7   GLN C CB  1 
ATOM   1710 C CG  . GLN C 1 8   ? -29.91274 55.92536 26.62764  1.000 43.26094 ? 7   GLN C CG  1 
ATOM   1711 C CD  . GLN C 1 8   ? -31.00784 56.94268 26.94406  1.000 49.80219 ? 7   GLN C CD  1 
ATOM   1712 O OE1 . GLN C 1 8   ? -31.85580 57.24743 26.09582  1.000 49.21769 ? 7   GLN C OE1 1 
ATOM   1713 N NE2 . GLN C 1 8   ? -30.97954 57.48786 28.15815  1.000 45.46513 ? 7   GLN C NE2 1 
ATOM   1714 N N   . VAL C 1 9   ? -30.54168 52.46478 23.69701  1.000 42.25009 ? 8   VAL C N   1 
ATOM   1715 C CA  . VAL C 1 9   ? -31.18710 51.31094 23.07080  1.000 42.65104 ? 8   VAL C CA  1 
ATOM   1716 C C   . VAL C 1 9   ? -30.23420 50.12092 23.02201  1.000 48.88488 ? 8   VAL C C   1 
ATOM   1717 O O   . VAL C 1 9   ? -30.65421 48.96785 23.18374  1.000 48.09182 ? 8   VAL C O   1 
ATOM   1718 C CB  . VAL C 1 9   ? -31.71629 51.67691 21.67295  1.000 41.35343 ? 8   VAL C CB  1 
ATOM   1719 C CG1 . VAL C 1 9   ? -32.08048 50.44041 20.90834  1.000 42.47231 ? 8   VAL C CG1 1 
ATOM   1720 C CG2 . VAL C 1 9   ? -32.93706 52.57987 21.79248  1.000 46.02876 ? 8   VAL C CG2 1 
ATOM   1721 N N   . ASN C 1 10  ? -28.93354 50.37815 22.82895  1.000 47.32203 ? 9   ASN C N   1 
ATOM   1722 C CA  . ASN C 1 10  ? -27.96439 49.28575 22.78807  1.000 44.89003 ? 9   ASN C CA  1 
ATOM   1723 C C   . ASN C 1 10  ? -27.68018 48.73446 24.17479  1.000 41.50635 ? 9   ASN C C   1 
ATOM   1724 O O   . ASN C 1 10  ? -27.53750 47.52021 24.34943  1.000 45.09936 ? 9   ASN C O   1 
ATOM   1725 C CB  . ASN C 1 10  ? -26.66243 49.74613 22.13309  1.000 48.11281 ? 9   ASN C CB  1 
ATOM   1726 C CG  . ASN C 1 10  ? -26.49756 49.18808 20.73996  1.000 51.86912 ? 9   ASN C CG  1 
ATOM   1727 O OD1 . ASN C 1 10  ? -27.44933 49.15700 19.95271  1.000 56.18028 ? 9   ASN C OD1 1 
ATOM   1728 N ND2 . ASN C 1 10  ? -25.29503 48.71223 20.43211  1.000 53.49853 ? 9   ASN C ND2 1 
ATOM   1729 N N   . TRP C 1 11  ? -27.55881 49.60945 25.16563  1.000 39.16562 ? 10  TRP C N   1 
ATOM   1730 C CA  . TRP C 1 11  ? -27.32814 49.14201 26.52248  1.000 37.42228 ? 10  TRP C CA  1 
ATOM   1731 C C   . TRP C 1 11  ? -28.52679 48.35082 27.03666  1.000 38.10899 ? 10  TRP C C   1 
ATOM   1732 O O   . TRP C 1 11  ? -28.36809 47.28857 27.65071  1.000 39.60226 ? 10  TRP C O   1 
ATOM   1733 C CB  . TRP C 1 11  ? -27.03708 50.33633 27.41624  1.000 34.70305 ? 10  TRP C CB  1 
ATOM   1734 C CG  . TRP C 1 11  ? -26.59818 49.97358 28.76160  1.000 34.59735 ? 10  TRP C CG  1 
ATOM   1735 C CD1 . TRP C 1 11  ? -26.23152 48.74130 29.19958  1.000 34.41007 ? 10  TRP C CD1 1 
ATOM   1736 C CD2 . TRP C 1 11  ? -26.45222 50.85863 29.86679  1.000 36.96802 ? 10  TRP C CD2 1 
ATOM   1737 N NE1 . TRP C 1 11  ? -25.87005 48.79962 30.52202  1.000 36.67622 ? 10  TRP C NE1 1 
ATOM   1738 C CE2 . TRP C 1 11  ? -25.99588 50.09307 30.95501  1.000 37.58947 ? 10  TRP C CE2 1 
ATOM   1739 C CE3 . TRP C 1 11  ? -26.66690 52.22900 30.04443  1.000 39.54340 ? 10  TRP C CE3 1 
ATOM   1740 C CZ2 . TRP C 1 11  ? -25.75413 50.64866 32.20744  1.000 37.53038 ? 10  TRP C CZ2 1 
ATOM   1741 C CZ3 . TRP C 1 11  ? -26.42448 52.78149 31.28671  1.000 38.79311 ? 10  TRP C CZ3 1 
ATOM   1742 C CH2 . TRP C 1 11  ? -25.97312 51.99285 32.35319  1.000 37.22764 ? 10  TRP C CH2 1 
ATOM   1743 N N   . ALA C 1 12  ? -29.73483 48.85547 26.78494  1.000 39.57547 ? 11  ALA C N   1 
ATOM   1744 C CA  . ALA C 1 12  ? -30.94233 48.18259 27.24056  1.000 37.35142 ? 11  ALA C CA  1 
ATOM   1745 C C   . ALA C 1 12  ? -31.10561 46.82565 26.56706  1.000 40.84649 ? 11  ALA C C   1 
ATOM   1746 O O   . ALA C 1 12  ? -31.43178 45.83481 27.23200  1.000 34.25266 ? 11  ALA C O   1 
ATOM   1747 C CB  . ALA C 1 12  ? -32.15461 49.06861 26.97105  1.000 34.38529 ? 11  ALA C CB  1 
ATOM   1748 N N   . LYS C 1 13  ? -30.88056 46.76088 25.24778  1.000 38.90174 ? 12  LYS C N   1 
ATOM   1749 C CA  . LYS C 1 13  ? -31.00621 45.48949 24.54681  1.000 38.39610 ? 12  LYS C CA  1 
ATOM   1750 C C   . LYS C 1 13  ? -30.05633 44.45933 25.13026  1.000 39.37753 ? 12  LYS C C   1 
ATOM   1751 O O   . LYS C 1 13  ? -30.40035 43.27501 25.23921  1.000 40.42698 ? 12  LYS C O   1 
ATOM   1752 C CB  . LYS C 1 13  ? -30.73315 45.65930 23.05140  1.000 38.81008 ? 12  LYS C CB  1 
ATOM   1753 C CG  . LYS C 1 13  ? -31.95354 45.90121 22.17269  1.000 42.18818 ? 12  LYS C CG  1 
ATOM   1754 C CD  . LYS C 1 13  ? -31.53800 46.69113 20.93672  1.000 49.07440 ? 12  LYS C CD  1 
ATOM   1755 C CE  . LYS C 1 13  ? -32.71985 47.14377 20.10469  1.000 54.42325 ? 12  LYS C CE  1 
ATOM   1756 N NZ  . LYS C 1 13  ? -33.26387 46.04776 19.26168  1.000 53.87353 ? 12  LYS C NZ  1 
ATOM   1757 N N   . SER C 1 14  ? -28.85405 44.89469 25.51690  1.000 39.10013 ? 13  SER C N   1 
ATOM   1758 C CA  . SER C 1 14  ? -27.88462 43.96852 26.09043  1.000 35.33797 ? 13  SER C CA  1 
ATOM   1759 C C   . SER C 1 14  ? -28.26839 43.56171 27.50977  1.000 37.30960 ? 13  SER C C   1 
ATOM   1760 O O   . SER C 1 14  ? -28.03771 42.41070 27.90684  1.000 35.57103 ? 13  SER C O   1 
ATOM   1761 C CB  . SER C 1 14  ? -26.49266 44.59292 26.06013  1.000 33.28151 ? 13  SER C CB  1 
ATOM   1762 O OG  . SER C 1 14  ? -26.23170 45.31558 27.25051  1.000 38.24979 ? 13  SER C OG  1 
ATOM   1763 N N   . ILE C 1 15  ? -28.84322 44.48537 28.28638  1.000 33.88737 ? 14  ILE C N   1 
ATOM   1764 C CA  . ILE C 1 15  ? -29.40583 44.12295 29.58487  1.000 34.99266 ? 14  ILE C CA  1 
ATOM   1765 C C   . ILE C 1 15  ? -30.46789 43.04083 29.41965  1.000 33.73059 ? 14  ILE C C   1 
ATOM   1766 O O   . ILE C 1 15  ? -30.50891 42.06517 30.18063  1.000 34.97819 ? 14  ILE C O   1 
ATOM   1767 C CB  . ILE C 1 15  ? -29.98023 45.36874 30.28908  1.000 35.27977 ? 14  ILE C CB  1 
ATOM   1768 C CG1 . ILE C 1 15  ? -28.85608 46.28269 30.77247  1.000 36.13476 ? 14  ILE C CG1 1 
ATOM   1769 C CG2 . ILE C 1 15  ? -30.89907 44.96780 31.44082  1.000 32.55438 ? 14  ILE C CG2 1 
ATOM   1770 C CD1 . ILE C 1 15  ? -29.27719 47.72278 30.93102  1.000 37.48338 ? 14  ILE C CD1 1 
ATOM   1771 N N   . ILE C 1 16  ? -31.33399 43.18840 28.41781  1.000 29.89520 ? 15  ILE C N   1 
ATOM   1772 C CA  . ILE C 1 16  ? -32.41783 42.23066 28.25179  1.000 32.61192 ? 15  ILE C CA  1 
ATOM   1773 C C   . ILE C 1 16  ? -31.87293 40.86992 27.84173  1.000 36.00098 ? 15  ILE C C   1 
ATOM   1774 O O   . ILE C 1 16  ? -32.29961 39.83386 28.37149  1.000 31.26417 ? 15  ILE C O   1 
ATOM   1775 C CB  . ILE C 1 16  ? -33.44945 42.76236 27.24568  1.000 33.07886 ? 15  ILE C CB  1 
ATOM   1776 C CG1 . ILE C 1 16  ? -34.11047 44.02551 27.80736  1.000 34.97106 ? 15  ILE C CG1 1 
ATOM   1777 C CG2 . ILE C 1 16  ? -34.45576 41.67588 26.88567  1.000 31.71487 ? 15  ILE C CG2 1 
ATOM   1778 C CD1 . ILE C 1 16  ? -35.05915 43.77286 28.96826  1.000 30.07884 ? 15  ILE C CD1 1 
ATOM   1779 N N   . GLU C 1 17  ? -30.90679 40.84258 26.91404  1.000 35.03908 ? 16  GLU C N   1 
ATOM   1780 C CA  . GLU C 1 17  ? -30.32514 39.56096 26.52777  1.000 35.24226 ? 16  GLU C CA  1 
ATOM   1781 C C   . GLU C 1 17  ? -29.62040 38.89822 27.70351  1.000 31.60744 ? 16  GLU C C   1 
ATOM   1782 O O   . GLU C 1 17  ? -29.66782 37.67142 27.84674  1.000 33.01950 ? 16  GLU C O   1 
ATOM   1783 C CB  . GLU C 1 17  ? -29.38029 39.72549 25.33650  1.000 34.92338 ? 16  GLU C CB  1 
ATOM   1784 C CG  . GLU C 1 17  ? -30.13981 39.91086 24.02482  1.000 40.80850 ? 16  GLU C CG  1 
ATOM   1785 C CD  . GLU C 1 17  ? -31.16155 38.79051 23.76068  1.000 46.85513 ? 16  GLU C CD  1 
ATOM   1786 O OE1 . GLU C 1 17  ? -32.38279 39.09228 23.62267  1.000 44.11799 ? 16  GLU C OE1 1 
ATOM   1787 O OE2 . GLU C 1 17  ? -30.74413 37.61156 23.70755  1.000 43.94493 ? 16  GLU C OE2 1 
ATOM   1788 N N   . LYS C 1 18  ? -28.98614 39.69018 28.57156  1.000 31.77380 ? 17  LYS C N   1 
ATOM   1789 C CA  . LYS C 1 18  ? -28.36879 39.11441 29.76404  1.000 31.81843 ? 17  LYS C CA  1 
ATOM   1790 C C   . LYS C 1 18  ? -29.41047 38.46245 30.66630  1.000 32.51290 ? 17  LYS C C   1 
ATOM   1791 O O   . LYS C 1 18  ? -29.19611 37.36035 31.18559  1.000 30.39960 ? 17  LYS C O   1 
ATOM   1792 C CB  . LYS C 1 18  ? -27.60399 40.18577 30.53291  1.000 32.38462 ? 17  LYS C CB  1 
ATOM   1793 C CG  . LYS C 1 18  ? -27.02302 39.68807 31.85106  1.000 31.26690 ? 17  LYS C CG  1 
ATOM   1794 C CD  . LYS C 1 18  ? -26.76837 40.81855 32.82589  1.000 39.17906 ? 17  LYS C CD  1 
ATOM   1795 C CE  . LYS C 1 18  ? -26.11042 41.98582 32.12089  1.000 41.48140 ? 17  LYS C CE  1 
ATOM   1796 N NZ  . LYS C 1 18  ? -25.15310 42.69226 33.01652  1.000 50.20762 ? 17  LYS C NZ  1 
ATOM   1797 N N   . GLU C 1 19  ? -30.55115 39.12548 30.85655  1.000 30.85069 ? 18  GLU C N   1 
ATOM   1798 C CA  . GLU C 1 19  ? -31.56767 38.59524 31.75858  1.000 30.07318 ? 18  GLU C CA  1 
ATOM   1799 C C   . GLU C 1 19  ? -32.26256 37.38406 31.14498  1.000 27.90190 ? 18  GLU C C   1 
ATOM   1800 O O   . GLU C 1 19  ? -32.44750 36.36095 31.81261  1.000 28.13583 ? 18  GLU C O   1 
ATOM   1801 C CB  . GLU C 1 19  ? -32.57041 39.69407 32.10175  1.000 26.71886 ? 18  GLU C CB  1 
ATOM   1802 C CG  . GLU C 1 19  ? -32.01987 40.80394 32.99788  1.000 27.40258 ? 18  GLU C CG  1 
ATOM   1803 C CD  . GLU C 1 19  ? -31.23686 40.28184 34.19411  1.000 30.98427 ? 18  GLU C CD  1 
ATOM   1804 O OE1 . GLU C 1 19  ? -31.76943 39.40503 34.90879  1.000 32.83904 ? 18  GLU C OE1 1 
ATOM   1805 O OE2 . GLU C 1 19  ? -30.11036 40.77415 34.44860  1.000 32.53015 ? 18  GLU C OE2 1 
ATOM   1806 N N   . VAL C 1 20  ? -32.64375 37.47509 29.86611  1.000 30.26254 ? 19  VAL C N   1 
ATOM   1807 C CA  . VAL C 1 20  ? -33.28667 36.34415 29.19990  1.000 27.51489 ? 19  VAL C CA  1 
ATOM   1808 C C   . VAL C 1 20  ? -32.41013 35.09064 29.30981  1.000 31.33763 ? 19  VAL C C   1 
ATOM   1809 O O   . VAL C 1 20  ? -32.89903 33.99079 29.61419  1.000 27.35162 ? 19  VAL C O   1 
ATOM   1810 C CB  . VAL C 1 20  ? -33.61301 36.70502 27.73731  1.000 30.88564 ? 19  VAL C CB  1 
ATOM   1811 C CG1 . VAL C 1 20  ? -33.93414 35.45281 26.94145  1.000 31.70650 ? 19  VAL C CG1 1 
ATOM   1812 C CG2 . VAL C 1 20  ? -34.79166 37.70024 27.65051  1.000 31.53817 ? 19  VAL C CG2 1 
ATOM   1813 N N   . GLU C 1 21  ? -31.08947 35.24544 29.13278  1.000 28.71074 ? 20  GLU C N   1 
ATOM   1814 C CA  . GLU C 1 21  ? -30.19159 34.09528 29.24689  1.000 30.38840 ? 20  GLU C CA  1 
ATOM   1815 C C   . GLU C 1 21  ? -30.16579 33.53644 30.66726  1.000 30.72076 ? 20  GLU C C   1 
ATOM   1816 O O   . GLU C 1 21  ? -30.14860 32.31330 30.84635  1.000 28.76109 ? 20  GLU C O   1 
ATOM   1817 C CB  . GLU C 1 21  ? -28.77421 34.45992 28.77802  1.000 31.68357 ? 20  GLU C CB  1 
ATOM   1818 C CG  . GLU C 1 21  ? -27.64648 33.49761 29.21822  1.000 37.40073 ? 20  GLU C CG  1 
ATOM   1819 C CD  . GLU C 1 21  ? -26.27931 33.80206 28.56081  1.000 41.20569 ? 20  GLU C CD  1 
ATOM   1820 O OE1 . GLU C 1 21  ? -26.21255 34.02824 27.31460  1.000 42.82073 ? 20  GLU C OE1 1 
ATOM   1821 O OE2 . GLU C 1 21  ? -25.25131 33.84546 29.28240  1.000 46.16073 ? 20  GLU C OE2 1 
ATOM   1822 N N   . ALA C 1 22  ? -30.19940 34.40820 31.68477  1.000 29.60840 ? 21  ALA C N   1 
ATOM   1823 C CA  . ALA C 1 22  ? -30.26898 33.94687 33.06753  1.000 27.82975 ? 21  ALA C CA  1 
ATOM   1824 C C   . ALA C 1 22  ? -31.52398 33.11508 33.30489  1.000 27.94272 ? 21  ALA C C   1 
ATOM   1825 O O   . ALA C 1 22  ? -31.46292 32.03431 33.90513  1.000 28.38526 ? 21  ALA C O   1 
ATOM   1826 C CB  . ALA C 1 22  ? -30.22642 35.14155 34.02670  1.000 30.24783 ? 21  ALA C CB  1 
ATOM   1827 N N   . TRP C 1 23  ? -32.67611 33.60129 32.82770  1.000 26.60150 ? 22  TRP C N   1 
ATOM   1828 C CA  . TRP C 1 23  ? -33.92257 32.85430 32.99775  1.000 27.08197 ? 22  TRP C CA  1 
ATOM   1829 C C   . TRP C 1 23  ? -33.89616 31.55476 32.19196  1.000 29.32380 ? 22  TRP C C   1 
ATOM   1830 O O   . TRP C 1 23  ? -34.34835 30.50088 32.66805  1.000 25.00112 ? 22  TRP C O   1 
ATOM   1831 C CB  . TRP C 1 23  ? -35.11996 33.72488 32.59686  1.000 21.05437 ? 22  TRP C CB  1 
ATOM   1832 C CG  . TRP C 1 23  ? -35.49855 34.77877 33.62294  1.000 23.48936 ? 22  TRP C CG  1 
ATOM   1833 C CD1 . TRP C 1 23  ? -34.95436 36.02081 33.76532  1.000 23.56490 ? 22  TRP C CD1 1 
ATOM   1834 C CD2 . TRP C 1 23  ? -36.50756 34.66629 34.64103  1.000 24.22471 ? 22  TRP C CD2 1 
ATOM   1835 N NE1 . TRP C 1 23  ? -35.55866 36.69094 34.80598  1.000 27.17269 ? 22  TRP C NE1 1 
ATOM   1836 C CE2 . TRP C 1 23  ? -36.51628 35.88054 35.35959  1.000 28.52913 ? 22  TRP C CE2 1 
ATOM   1837 C CE3 . TRP C 1 23  ? -37.41087 33.66071 35.00406  1.000 23.64040 ? 22  TRP C CE3 1 
ATOM   1838 C CZ2 . TRP C 1 23  ? -37.38814 36.11413 36.43330  1.000 25.36669 ? 22  TRP C CZ2 1 
ATOM   1839 C CZ3 . TRP C 1 23  ? -38.27844 33.89335 36.06196  1.000 23.46792 ? 22  TRP C CZ3 1 
ATOM   1840 C CH2 . TRP C 1 23  ? -38.25873 35.11020 36.76520  1.000 24.78019 ? 22  TRP C CH2 1 
ATOM   1841 N N   . GLU C 1 24  ? -33.33943 31.60123 30.98267  1.000 26.99288 ? 23  GLU C N   1 
ATOM   1842 C CA  . GLU C 1 24  ? -33.30885 30.40883 30.14652  1.000 25.88692 ? 23  GLU C CA  1 
ATOM   1843 C C   . GLU C 1 24  ? -32.30447 29.38444 30.64969  1.000 24.85516 ? 23  GLU C C   1 
ATOM   1844 O O   . GLU C 1 24  ? -32.36709 28.22217 30.24286  1.000 28.19572 ? 23  GLU C O   1 
ATOM   1845 C CB  . GLU C 1 24  ? -33.01786 30.79686 28.69206  1.000 28.02310 ? 23  GLU C CB  1 
ATOM   1846 C CG  . GLU C 1 24  ? -34.23363 31.41225 28.02876  1.000 27.87165 ? 23  GLU C CG  1 
ATOM   1847 C CD  . GLU C 1 24  ? -34.00273 31.81969 26.58944  1.000 37.58125 ? 23  GLU C CD  1 
ATOM   1848 O OE1 . GLU C 1 24  ? -32.83376 31.83330 26.13137  1.000 33.96718 ? 23  GLU C OE1 1 
ATOM   1849 O OE2 . GLU C 1 24  ? -35.00924 32.12505 25.91367  1.000 38.18032 ? 23  GLU C OE2 1 
ATOM   1850 N N   . ALA C 1 25  ? -31.40704 29.77693 31.54716  1.000 25.96427 ? 24  ALA C N   1 
ATOM   1851 C CA  . ALA C 1 25  ? -30.48723 28.82462 32.15395  1.000 28.68345 ? 24  ALA C CA  1 
ATOM   1852 C C   . ALA C 1 25  ? -31.15140 27.95763 33.21777  1.000 28.51977 ? 24  ALA C C   1 
ATOM   1853 O O   . ALA C 1 25  ? -30.57099 26.94549 33.62529  1.000 29.28520 ? 24  ALA C O   1 
ATOM   1854 C CB  . ALA C 1 25  ? -29.30403 29.56851 32.76967  1.000 26.74241 ? 24  ALA C CB  1 
ATOM   1855 N N   . ILE C 1 26  ? -32.34859 28.32863 33.67931  1.000 25.95906 ? 25  ILE C N   1 
ATOM   1856 C CA  . ILE C 1 26  ? -32.99408 27.57944 34.75848  1.000 26.30093 ? 25  ILE C CA  1 
ATOM   1857 C C   . ILE C 1 26  ? -33.25428 26.13771 34.33373  1.000 28.96711 ? 25  ILE C C   1 
ATOM   1858 O O   . ILE C 1 26  ? -32.99277 25.19210 35.08896  1.000 30.54184 ? 25  ILE C O   1 
ATOM   1859 C CB  . ILE C 1 26  ? -34.29647 28.27520 35.18946  1.000 28.49638 ? 25  ILE C CB  1 
ATOM   1860 C CG1 . ILE C 1 26  ? -34.00253 29.63670 35.81256  1.000 25.50922 ? 25  ILE C CG1 1 
ATOM   1861 C CG2 . ILE C 1 26  ? -35.06917 27.39710 36.15905  1.000 26.60894 ? 25  ILE C CG2 1 
ATOM   1862 C CD1 . ILE C 1 26  ? -35.27093 30.41999 36.09969  1.000 28.33989 ? 25  ILE C CD1 1 
ATOM   1863 N N   . GLY C 1 27  ? -33.78287 25.94528 33.12707  1.000 26.31310 ? 26  GLY C N   1 
ATOM   1864 C CA  . GLY C 1 27  ? -34.08144 24.61678 32.63146  1.000 26.15807 ? 26  GLY C CA  1 
ATOM   1865 C C   . GLY C 1 27  ? -35.54507 24.22097 32.66273  1.000 28.15057 ? 26  GLY C C   1 
ATOM   1866 O O   . GLY C 1 27  ? -35.85232 23.04515 32.44199  1.000 26.99859 ? 26  GLY C O   1 
ATOM   1867 N N   . VAL C 1 28  ? -36.45234 25.14692 32.96763  1.000 25.68926 ? 27  VAL C N   1 
ATOM   1868 C CA  . VAL C 1 28  ? -37.88442 24.92650 32.79999  1.000 26.60860 ? 27  VAL C CA  1 
ATOM   1869 C C   . VAL C 1 28  ? -38.39911 25.99770 31.84910  1.000 27.53361 ? 27  VAL C C   1 
ATOM   1870 O O   . VAL C 1 28  ? -37.70277 26.96422 31.54340  1.000 28.06810 ? 27  VAL C O   1 
ATOM   1871 C CB  . VAL C 1 28  ? -38.64833 24.94421 34.14200  1.000 26.46644 ? 27  VAL C CB  1 
ATOM   1872 C CG1 . VAL C 1 28  ? -38.13044 23.85106 35.03535  1.000 25.60759 ? 27  VAL C CG1 1 
ATOM   1873 C CG2 . VAL C 1 28  ? -38.50704 26.30067 34.84178  1.000 25.22410 ? 27  VAL C CG2 1 
ATOM   1874 N N   . ASP C 1 29  ? -39.62210 25.80616 31.35881  1.000 25.76620 ? 28  ASP C N   1 
ATOM   1875 C CA  . ASP C 1 29  ? -40.18616 26.73819 30.38712  1.000 26.17539 ? 28  ASP C CA  1 
ATOM   1876 C C   . ASP C 1 29  ? -40.32665 28.13872 30.99119  1.000 28.45037 ? 28  ASP C C   1 
ATOM   1877 O O   . ASP C 1 29  ? -41.01135 28.32166 32.00209  1.000 29.51770 ? 28  ASP C O   1 
ATOM   1878 C CB  . ASP C 1 29  ? -41.53905 26.21677 29.90880  1.000 25.51777 ? 28  ASP C CB  1 
ATOM   1879 C CG  . ASP C 1 29  ? -42.19378 27.12621 28.87392  1.000 35.46316 ? 28  ASP C CG  1 
ATOM   1880 O OD1 . ASP C 1 29  ? -41.53614 28.06315 28.36845  1.000 32.71173 ? 28  ASP C OD1 1 
ATOM   1881 O OD2 . ASP C 1 29  ? -43.38685 26.90201 28.56563  1.000 38.69953 ? 28  ASP C OD2 1 
ATOM   1882 N N   . VAL C 1 30  ? -39.68201 29.12501 30.36199  1.000 27.69502 ? 29  VAL C N   1 
ATOM   1883 C CA  . VAL C 1 30  ? -39.74798 30.52592 30.77961  1.000 28.27054 ? 29  VAL C CA  1 
ATOM   1884 C C   . VAL C 1 30  ? -40.06238 31.41701 29.58238  1.000 29.25000 ? 29  VAL C C   1 
ATOM   1885 O O   . VAL C 1 30  ? -39.76190 32.61792 29.59414  1.000 26.95504 ? 29  VAL C O   1 
ATOM   1886 C CB  . VAL C 1 30  ? -38.43792 30.98277 31.45191  1.000 27.52530 ? 29  VAL C CB  1 
ATOM   1887 C CG1 . VAL C 1 30  ? -38.14239 30.14042 32.72136  1.000 24.58346 ? 29  VAL C CG1 1 
ATOM   1888 C CG2 . VAL C 1 30  ? -37.27258 30.92578 30.45994  1.000 26.56404 ? 29  VAL C CG2 1 
ATOM   1889 N N   . ARG C 1 31  ? -40.68452 30.84689 28.54617  1.000 26.94102 ? 30  ARG C N   1 
ATOM   1890 C CA  . ARG C 1 31  ? -40.91145 31.61054 27.31794  1.000 27.88985 ? 30  ARG C CA  1 
ATOM   1891 C C   . ARG C 1 31  ? -41.77074 32.84195 27.57146  1.000 28.51812 ? 30  ARG C C   1 
ATOM   1892 O O   . ARG C 1 31  ? -41.57063 33.88803 26.94000  1.000 28.64960 ? 30  ARG C O   1 
ATOM   1893 C CB  . ARG C 1 31  ? -41.55626 30.72308 26.26083  1.000 29.37120 ? 30  ARG C CB  1 
ATOM   1894 C CG  . ARG C 1 31  ? -40.57240 29.72462 25.64885  1.000 36.16584 ? 30  ARG C CG  1 
ATOM   1895 C CD  . ARG C 1 31  ? -41.22464 28.90406 24.56498  1.000 37.90062 ? 30  ARG C CD  1 
ATOM   1896 N NE  . ARG C 1 31  ? -41.95538 27.78992 25.14862  1.000 39.24470 ? 30  ARG C NE  1 
ATOM   1897 C CZ  . ARG C 1 31  ? -43.25164 27.57952 24.97835  1.000 43.05202 ? 30  ARG C CZ  1 
ATOM   1898 N NH1 . ARG C 1 31  ? -43.97561 28.34777 24.18179  1.000 49.28432 ? 30  ARG C NH1 1 
ATOM   1899 N NH2 . ARG C 1 31  ? -43.83766 26.57914 25.63038  1.000 45.75053 ? 30  ARG C NH2 1 
ATOM   1900 N N   . GLU C 1 32  ? -42.73472 32.74182 28.49059  1.000 26.36942 ? 31  GLU C N   1 
ATOM   1901 C CA  . GLU C 1 32  ? -43.58045 33.89525 28.76483  1.000 26.10760 ? 31  GLU C CA  1 
ATOM   1902 C C   . GLU C 1 32  ? -42.77316 35.01825 29.39453  1.000 26.89324 ? 31  GLU C C   1 
ATOM   1903 O O   . GLU C 1 32  ? -42.99457 36.19653 29.08954  1.000 28.73190 ? 31  GLU C O   1 
ATOM   1904 C CB  . GLU C 1 32  ? -44.76232 33.50177 29.66241  1.000 24.99988 ? 31  GLU C CB  1 
ATOM   1905 C CG  . GLU C 1 32  ? -45.78060 34.62233 29.81267  1.000 28.64238 ? 31  GLU C CG  1 
ATOM   1906 C CD  . GLU C 1 32  ? -47.03527 34.21805 30.57431  1.000 32.61853 ? 31  GLU C CD  1 
ATOM   1907 O OE1 . GLU C 1 32  ? -47.27663 33.00005 30.76506  1.000 30.22220 ? 31  GLU C OE1 1 
ATOM   1908 O OE2 . GLU C 1 32  ? -47.79771 35.13012 30.96084  1.000 32.41697 ? 31  GLU C OE2 1 
ATOM   1909 N N   . VAL C 1 33  ? -41.83432 34.68103 30.27962  1.000 24.71815 ? 32  VAL C N   1 
ATOM   1910 C CA  . VAL C 1 33  ? -41.01924 35.72573 30.89124  1.000 24.03601 ? 32  VAL C CA  1 
ATOM   1911 C C   . VAL C 1 33  ? -40.03239 36.28654 29.87271  1.000 27.32716 ? 32  VAL C C   1 
ATOM   1912 O O   . VAL C 1 33  ? -39.85168 37.50785 29.76852  1.000 24.55942 ? 32  VAL C O   1 
ATOM   1913 C CB  . VAL C 1 33  ? -40.31644 35.19066 32.15095  1.000 28.25050 ? 32  VAL C CB  1 
ATOM   1914 C CG1 . VAL C 1 33  ? -39.31474 36.20747 32.67482  1.000 25.48134 ? 32  VAL C CG1 1 
ATOM   1915 C CG2 . VAL C 1 33  ? -41.35488 34.84968 33.24504  1.000 23.57624 ? 32  VAL C CG2 1 
ATOM   1916 N N   . ALA C 1 34  ? -39.41333 35.41115 29.07116  1.000 29.16018 ? 33  ALA C N   1 
ATOM   1917 C CA  . ALA C 1 34  ? -38.51464 35.88635 28.02289  1.000 29.03926 ? 33  ALA C CA  1 
ATOM   1918 C C   . ALA C 1 34  ? -39.23674 36.82396 27.06769  1.000 28.01231 ? 33  ALA C C   1 
ATOM   1919 O O   . ALA C 1 34  ? -38.71955 37.89290 26.73350  1.000 31.95875 ? 33  ALA C O   1 
ATOM   1920 C CB  . ALA C 1 34  ? -37.90835 34.70931 27.25735  1.000 28.08357 ? 33  ALA C CB  1 
ATOM   1921 N N   . ALA C 1 35  ? -40.44450 36.45461 26.63790  1.000 29.61595 ? 34  ALA C N   1 
ATOM   1922 C CA  . ALA C 1 35  ? -41.18496 37.30168 25.70735  1.000 29.66555 ? 34  ALA C CA  1 
ATOM   1923 C C   . ALA C 1 35  ? -41.57407 38.63359 26.33794  1.000 32.91575 ? 34  ALA C C   1 
ATOM   1924 O O   . ALA C 1 35  ? -41.56904 39.66447 25.65158  1.000 30.81183 ? 34  ALA C O   1 
ATOM   1925 C CB  . ALA C 1 35  ? -42.43213 36.57441 25.20743  1.000 30.89986 ? 34  ALA C CB  1 
ATOM   1926 N N   . PHE C 1 36  ? -41.92928 38.63745 27.62894  1.000 30.19868 ? 35  PHE C N   1 
ATOM   1927 C CA  . PHE C 1 36  ? -42.21699 39.89898 28.30606  1.000 25.36134 ? 35  PHE C CA  1 
ATOM   1928 C C   . PHE C 1 36  ? -40.97943 40.78660 28.34285  1.000 28.17672 ? 35  PHE C C   1 
ATOM   1929 O O   . PHE C 1 36  ? -41.04675 41.97904 28.01492  1.000 27.06848 ? 35  PHE C O   1 
ATOM   1930 C CB  . PHE C 1 36  ? -42.73385 39.64387 29.72548  1.000 27.97806 ? 35  PHE C CB  1 
ATOM   1931 C CG  . PHE C 1 36  ? -42.66524 40.85882 30.62227  1.000 25.95000 ? 35  PHE C CG  1 
ATOM   1932 C CD1 . PHE C 1 36  ? -43.50691 41.94108 30.40941  1.000 25.28993 ? 35  PHE C CD1 1 
ATOM   1933 C CD2 . PHE C 1 36  ? -41.74692 40.92080 31.66287  1.000 25.22620 ? 35  PHE C CD2 1 
ATOM   1934 C CE1 . PHE C 1 36  ? -43.43293 43.06875 31.21984  1.000 27.17826 ? 35  PHE C CE1 1 
ATOM   1935 C CE2 . PHE C 1 36  ? -41.67189 42.03226 32.48144  1.000 25.66346 ? 35  PHE C CE2 1 
ATOM   1936 C CZ  . PHE C 1 36  ? -42.51812 43.11226 32.25984  1.000 28.15061 ? 35  PHE C CZ  1 
ATOM   1937 N N   . LEU C 1 37  ? -39.83344 40.22063 28.74586  1.000 24.92254 ? 36  LEU C N   1 
ATOM   1938 C CA  . LEU C 1 37  ? -38.61215 41.01729 28.80655  1.000 29.04305 ? 36  LEU C CA  1 
ATOM   1939 C C   . LEU C 1 37  ? -38.28157 41.62305 27.44559  1.000 33.46226 ? 36  LEU C C   1 
ATOM   1940 O O   . LEU C 1 37  ? -37.87216 42.78636 27.35826  1.000 33.95974 ? 36  LEU C O   1 
ATOM   1941 C CB  . LEU C 1 37  ? -37.43932 40.17354 29.31425  1.000 27.02699 ? 36  LEU C CB  1 
ATOM   1942 C CG  . LEU C 1 37  ? -37.52859 39.74070 30.78949  1.000 30.61278 ? 36  LEU C CG  1 
ATOM   1943 C CD1 . LEU C 1 37  ? -36.47911 38.70110 31.13966  1.000 23.75088 ? 36  LEU C CD1 1 
ATOM   1944 C CD2 . LEU C 1 37  ? -37.43159 40.94549 31.71655  1.000 26.53006 ? 36  LEU C CD2 1 
ATOM   1945 N N   . ARG C 1 38  ? -38.47728 40.85920 26.37254  1.000 29.19743 ? 37  ARG C N   1 
ATOM   1946 C CA  . ARG C 1 38  ? -38.14196 41.34625 25.04504  1.000 31.12619 ? 37  ARG C CA  1 
ATOM   1947 C C   . ARG C 1 38  ? -39.16852 42.32456 24.50125  1.000 35.80114 ? 37  ARG C C   1 
ATOM   1948 O O   . ARG C 1 38  ? -38.87040 43.03149 23.53413  1.000 35.10703 ? 37  ARG C O   1 
ATOM   1949 C CB  . ARG C 1 38  ? -37.98520 40.16823 24.08978  1.000 31.05773 ? 37  ARG C CB  1 
ATOM   1950 C CG  . ARG C 1 38  ? -36.67631 39.45523 24.31157  1.000 32.45614 ? 37  ARG C CG  1 
ATOM   1951 C CD  . ARG C 1 38  ? -36.49838 38.27199 23.39484  1.000 30.69623 ? 37  ARG C CD  1 
ATOM   1952 N NE  . ARG C 1 38  ? -35.10082 37.86374 23.42058  1.000 32.44703 ? 37  ARG C NE  1 
ATOM   1953 C CZ  . ARG C 1 38  ? -34.68822 36.60870 23.45114  1.000 35.23503 ? 37  ARG C CZ  1 
ATOM   1954 N NH1 . ARG C 1 38  ? -35.54890 35.59707 23.45918  1.000 33.94947 ? 37  ARG C NH1 1 
ATOM   1955 N NH2 . ARG C 1 38  ? -33.38207 36.36179 23.46034  1.000 34.19818 ? 37  ARG C NH2 1 
ATOM   1956 N N   . SER C 1 39  ? -40.36115 42.38910 25.10028  1.000 31.69197 ? 38  SER C N   1 
ATOM   1957 C CA  . SER C 1 39  ? -41.38185 43.33552 24.66161  1.000 30.24345 ? 38  SER C CA  1 
ATOM   1958 C C   . SER C 1 39  ? -41.16604 44.73698 25.21025  1.000 31.58328 ? 38  SER C C   1 
ATOM   1959 O O   . SER C 1 39  ? -41.81695 45.67490 24.73767  1.000 32.35940 ? 38  SER C O   1 
ATOM   1960 C CB  . SER C 1 39  ? -42.76720 42.86078 25.09057  1.000 27.25602 ? 38  SER C CB  1 
ATOM   1961 O OG  . SER C 1 39  ? -42.94943 43.10471 26.47310  1.000 30.80424 ? 38  SER C OG  1 
ATOM   1962 N N   . ILE C 1 40  ? -40.29349 44.89908 26.20650  1.000 28.72926 ? 39  ILE C N   1 
ATOM   1963 C CA  . ILE C 1 40  ? -40.12713 46.19776 26.84007  1.000 28.85986 ? 39  ILE C CA  1 
ATOM   1964 C C   . ILE C 1 40  ? -39.49784 47.16294 25.84456  1.000 37.98770 ? 39  ILE C C   1 
ATOM   1965 O O   . ILE C 1 40  ? -38.47019 46.85922 25.21889  1.000 34.99228 ? 39  ILE C O   1 
ATOM   1966 C CB  . ILE C 1 40  ? -39.29483 46.07469 28.12146  1.000 28.39448 ? 39  ILE C CB  1 
ATOM   1967 C CG1 . ILE C 1 40  ? -39.95073 45.07716 29.09180  1.000 29.24187 ? 39  ILE C CG1 1 
ATOM   1968 C CG2 . ILE C 1 40  ? -39.19229 47.42921 28.79854  1.000 28.54141 ? 39  ILE C CG2 1 
ATOM   1969 C CD1 . ILE C 1 40  ? -39.03983 44.64531 30.23627  1.000 24.07252 ? 39  ILE C CD1 1 
ATOM   1970 N N   . SER C 1 41  ? -40.11656 48.33787 25.69568  1.000 36.35695 ? 40  SER C N   1 
ATOM   1971 C CA  . SER C 1 41  ? -39.86809 49.22010 24.56545  1.000 36.03072 ? 40  SER C CA  1 
ATOM   1972 C C   . SER C 1 41  ? -39.35309 50.58987 24.97609  1.000 42.74634 ? 40  SER C C   1 
ATOM   1973 O O   . SER C 1 41  ? -39.30688 51.49433 24.13528  1.000 46.29115 ? 40  SER C O   1 
ATOM   1974 C CB  . SER C 1 41  ? -41.14447 49.37328 23.73743  1.000 38.30019 ? 40  SER C CB  1 
ATOM   1975 O OG  . SER C 1 41  ? -42.22059 49.82260 24.54643  1.000 37.66217 ? 40  SER C OG  1 
ATOM   1976 N N   . ASP C 1 42  ? -38.97087 50.77315 26.23650  1.000 36.46177 ? 41  ASP C N   1 
ATOM   1977 C CA  . ASP C 1 42  ? -38.36956 52.01494 26.70529  1.000 38.54215 ? 41  ASP C CA  1 
ATOM   1978 C C   . ASP C 1 42  ? -37.00977 51.68993 27.30852  1.000 41.69329 ? 41  ASP C C   1 
ATOM   1979 O O   . ASP C 1 42  ? -36.93427 51.03068 28.35550  1.000 36.75732 ? 41  ASP C O   1 
ATOM   1980 C CB  . ASP C 1 42  ? -39.27428 52.70930 27.71715  1.000 38.74391 ? 41  ASP C CB  1 
ATOM   1981 C CG  . ASP C 1 42  ? -38.76807 54.08695 28.10555  1.000 43.61425 ? 41  ASP C CG  1 
ATOM   1982 O OD1 . ASP C 1 42  ? -37.64792 54.20031 28.65327  1.000 44.73483 ? 41  ASP C OD1 1 
ATOM   1983 O OD2 . ASP C 1 42  ? -39.49390 55.06416 27.85041  1.000 46.92084 ? 41  ASP C OD2 1 
ATOM   1984 N N   . ALA C 1 43  ? -35.94422 52.18307 26.65701  1.000 39.16028 ? 42  ALA C N   1 
ATOM   1985 C CA  . ALA C 1 43  ? -34.57925 51.85104 27.06244  1.000 36.02545 ? 42  ALA C CA  1 
ATOM   1986 C C   . ALA C 1 43  ? -34.25687 52.36790 28.45809  1.000 35.73637 ? 42  ALA C C   1 
ATOM   1987 O O   . ALA C 1 43  ? -33.55772 51.69852 29.22833  1.000 34.85893 ? 42  ALA C O   1 
ATOM   1988 C CB  . ALA C 1 43  ? -33.57764 52.40710 26.04828  1.000 38.31614 ? 42  ALA C CB  1 
ATOM   1989 N N   . ARG C 1 44  ? -34.74806 53.55730 28.80932  1.000 39.05514 ? 43  ARG C N   1 
ATOM   1990 C CA  . ARG C 1 44  ? -34.40361 54.11230 30.11665  1.000 38.07625 ? 43  ARG C CA  1 
ATOM   1991 C C   . ARG C 1 44  ? -35.10148 53.38113 31.25830  1.000 34.95475 ? 43  ARG C C   1 
ATOM   1992 O O   . ARG C 1 44  ? -34.56189 53.32490 32.36748  1.000 40.20450 ? 43  ARG C O   1 
ATOM   1993 C CB  . ARG C 1 44  ? -34.72217 55.60106 30.14988  1.000 41.60932 ? 43  ARG C CB  1 
ATOM   1994 C CG  . ARG C 1 44  ? -34.46493 56.27719 28.81192  1.000 50.52779 ? 43  ARG C CG  1 
ATOM   1995 C CD  . ARG C 1 44  ? -35.36084 57.47954 28.62517  1.000 54.27130 ? 43  ARG C CD  1 
ATOM   1996 N NE  . ARG C 1 44  ? -36.70657 57.08522 28.22190  1.000 57.90981 ? 43  ARG C NE  1 
ATOM   1997 C CZ  . ARG C 1 44  ? -37.57594 57.88972 27.62560  1.000 57.92445 ? 43  ARG C CZ  1 
ATOM   1998 N NH1 . ARG C 1 44  ? -37.28074 59.15087 27.35932  1.000 59.51850 ? 43  ARG C NH1 1 
ATOM   1999 N NH2 . ARG C 1 44  ? -38.77119 57.41730 27.28658  1.000 54.78890 ? 43  ARG C NH2 1 
ATOM   2000 N N   . VAL C 1 45  ? -36.28347 52.80939 31.02005  1.000 36.44085 ? 44  VAL C N   1 
ATOM   2001 C CA  . VAL C 1 45  ? -36.91095 51.99341 32.05839  1.000 35.32407 ? 44  VAL C CA  1 
ATOM   2002 C C   . VAL C 1 45  ? -36.10091 50.72510 32.29453  1.000 35.27068 ? 44  VAL C C   1 
ATOM   2003 O O   . VAL C 1 45  ? -35.92101 50.28759 33.44060  1.000 34.53189 ? 44  VAL C O   1 
ATOM   2004 C CB  . VAL C 1 45  ? -38.37567 51.67673 31.69713  1.000 35.34145 ? 44  VAL C CB  1 
ATOM   2005 C CG1 . VAL C 1 45  ? -39.02406 50.80894 32.79007  1.000 36.32621 ? 44  VAL C CG1 1 
ATOM   2006 C CG2 . VAL C 1 45  ? -39.16923 52.97347 31.51536  1.000 37.25580 ? 44  VAL C CG2 1 
ATOM   2007 N N   . ILE C 1 46  ? -35.58476 50.12444 31.21941  1.000 33.34577 ? 45  ILE C N   1 
ATOM   2008 C CA  . ILE C 1 46  ? -34.74431 48.93976 31.36488  1.000 33.81200 ? 45  ILE C CA  1 
ATOM   2009 C C   . ILE C 1 46  ? -33.47200 49.28950 32.12089  1.000 36.20923 ? 45  ILE C C   1 
ATOM   2010 O O   . ILE C 1 46  ? -33.11572 48.64220 33.11518  1.000 33.94126 ? 45  ILE C O   1 
ATOM   2011 C CB  . ILE C 1 46  ? -34.43117 48.33676 29.98392  1.000 33.36265 ? 45  ILE C CB  1 
ATOM   2012 C CG1 . ILE C 1 46  ? -35.71459 47.84332 29.32798  1.000 29.86140 ? 45  ILE C CG1 1 
ATOM   2013 C CG2 . ILE C 1 46  ? -33.40384 47.21933 30.10595  1.000 32.89635 ? 45  ILE C CG2 1 
ATOM   2014 C CD1 . ILE C 1 46  ? -35.57851 47.56398 27.86566  1.000 35.66957 ? 45  ILE C CD1 1 
ATOM   2015 N N   . ILE C 1 47  ? -32.77881 50.33649 31.66468  1.000 34.62622 ? 46  ILE C N   1 
ATOM   2016 C CA  . ILE C 1 47  ? -31.50990 50.72804 32.26717  1.000 32.02925 ? 46  ILE C CA  1 
ATOM   2017 C C   . ILE C 1 47  ? -31.69285 51.04797 33.74106  1.000 35.15820 ? 46  ILE C C   1 
ATOM   2018 O O   . ILE C 1 47  ? -30.93709 50.56989 34.59666  1.000 38.66266 ? 46  ILE C O   1 
ATOM   2019 C CB  . ILE C 1 47  ? -30.91089 51.91891 31.50159  1.000 35.11623 ? 46  ILE C CB  1 
ATOM   2020 C CG1 . ILE C 1 47  ? -30.47295 51.46864 30.10100  1.000 33.71220 ? 46  ILE C CG1 1 
ATOM   2021 C CG2 . ILE C 1 47  ? -29.76756 52.52897 32.29943  1.000 38.25310 ? 46  ILE C CG2 1 
ATOM   2022 C CD1 . ILE C 1 47  ? -30.31146 52.59794 29.10914  1.000 36.18514 ? 46  ILE C CD1 1 
ATOM   2023 N N   . ASP C 1 48  ? -32.69939 51.86250 34.06431  1.000 33.79743 ? 47  ASP C N   1 
ATOM   2024 C CA  . ASP C 1 48  ? -32.91291 52.24616 35.45580  1.000 33.84202 ? 47  ASP C CA  1 
ATOM   2025 C C   . ASP C 1 48  ? -33.18817 51.03375 36.33894  1.000 36.49592 ? 47  ASP C C   1 
ATOM   2026 O O   . ASP C 1 48  ? -32.82279 51.02707 37.52174  1.000 35.48179 ? 47  ASP C O   1 
ATOM   2027 C CB  . ASP C 1 48  ? -34.06931 53.24252 35.54825  1.000 38.18942 ? 47  ASP C CB  1 
ATOM   2028 C CG  . ASP C 1 48  ? -33.69421 54.63798 35.05083  1.000 44.42419 ? 47  ASP C CG  1 
ATOM   2029 O OD1 . ASP C 1 48  ? -32.48906 54.92830 34.86980  1.000 45.26062 ? 47  ASP C OD1 1 
ATOM   2030 O OD2 . ASP C 1 48  ? -34.61916 55.44810 34.82837  1.000 43.91645 ? 47  ASP C OD2 1 
ATOM   2031 N N   . ASN C 1 49  ? -33.80511 49.99161 35.78565  1.000 34.60112 ? 48  ASN C N   1 
ATOM   2032 C CA  . ASN C 1 49  ? -34.18672 48.81783 36.55992  1.000 35.29794 ? 48  ASN C CA  1 
ATOM   2033 C C   . ASN C 1 49  ? -33.26714 47.62426 36.33169  1.000 36.45858 ? 48  ASN C C   1 
ATOM   2034 O O   . ASN C 1 49  ? -33.61413 46.51172 36.73535  1.000 33.58466 ? 48  ASN C O   1 
ATOM   2035 C CB  . ASN C 1 49  ? -35.63822 48.43650 36.24253  1.000 33.35232 ? 48  ASN C CB  1 
ATOM   2036 C CG  . ASN C 1 49  ? -36.63332 49.44776 36.79672  1.000 34.95685 ? 48  ASN C CG  1 
ATOM   2037 O OD1 . ASN C 1 49  ? -36.93307 49.43399 37.99056  1.000 33.41580 ? 48  ASN C OD1 1 
ATOM   2038 N ND2 . ASN C 1 49  ? -37.13547 50.33739 35.93861  1.000 28.71846 ? 48  ASN C ND2 1 
ATOM   2039 N N   . ARG C 1 50  ? -32.09491 47.83104 35.71593  1.000 35.93247 ? 49  ARG C N   1 
ATOM   2040 C CA  . ARG C 1 50  ? -31.24394 46.70213 35.33634  1.000 34.00168 ? 49  ARG C CA  1 
ATOM   2041 C C   . ARG C 1 50  ? -30.75912 45.91679 36.54976  1.000 33.55296 ? 49  ARG C C   1 
ATOM   2042 O O   . ARG C 1 50  ? -30.59184 44.69762 36.46894  1.000 32.36678 ? 49  ARG C O   1 
ATOM   2043 C CB  . ARG C 1 50  ? -30.04364 47.18918 34.51649  1.000 37.82318 ? 49  ARG C CB  1 
ATOM   2044 C CG  . ARG C 1 50  ? -29.14617 48.15685 35.26668  1.000 33.84230 ? 49  ARG C CG  1 
ATOM   2045 C CD  . ARG C 1 50  ? -28.13936 48.83664 34.36400  1.000 38.30304 ? 49  ARG C CD  1 
ATOM   2046 N NE  . ARG C 1 50  ? -27.12508 49.53162 35.14899  1.000 39.34474 ? 49  ARG C NE  1 
ATOM   2047 C CZ  . ARG C 1 50  ? -27.29515 50.72353 35.70726  1.000 43.14443 ? 49  ARG C CZ  1 
ATOM   2048 N NH1 . ARG C 1 50  ? -28.42331 51.40315 35.55810  1.000 40.62409 ? 49  ARG C NH1 1 
ATOM   2049 N NH2 . ARG C 1 50  ? -26.30630 51.25131 36.42665  1.000 39.94410 ? 49  ARG C NH2 1 
ATOM   2050 N N   . ASN C 1 51  ? -30.52486 46.58167 37.67639  1.000 29.94708 ? 50  ASN C N   1 
ATOM   2051 C CA  . ASN C 1 51  ? -30.09152 45.85811 38.86498  1.000 33.34627 ? 50  ASN C CA  1 
ATOM   2052 C C   . ASN C 1 51  ? -31.26789 45.34521 39.68710  1.000 33.50640 ? 50  ASN C C   1 
ATOM   2053 O O   . ASN C 1 51  ? -31.18960 44.25932 40.27047  1.000 33.98301 ? 50  ASN C O   1 
ATOM   2054 C CB  . ASN C 1 51  ? -29.18476 46.74974 39.72361  1.000 35.48570 ? 50  ASN C CB  1 
ATOM   2055 C CG  . ASN C 1 51  ? -27.89451 47.11921 39.00509  1.000 40.64750 ? 50  ASN C CG  1 
ATOM   2056 O OD1 . ASN C 1 51  ? -27.24858 46.26037 38.40031  1.000 39.20604 ? 50  ASN C OD1 1 
ATOM   2057 N ND2 . ASN C 1 51  ? -27.52139 48.39358 39.05436  1.000 38.01736 ? 50  ASN C ND2 1 
ATOM   2058 N N   . LEU C 1 52  ? -32.36941 46.09361 39.72902  1.000 32.72338 ? 51  LEU C N   1 
ATOM   2059 C CA  . LEU C 1 52  ? -33.52137 45.65431 40.51125  1.000 34.44699 ? 51  LEU C CA  1 
ATOM   2060 C C   . LEU C 1 52  ? -34.09077 44.34033 39.97701  1.000 29.73452 ? 51  LEU C C   1 
ATOM   2061 O O   . LEU C 1 52  ? -34.52778 43.48675 40.75656  1.000 29.55806 ? 51  LEU C O   1 
ATOM   2062 C CB  . LEU C 1 52  ? -34.58755 46.75531 40.52299  1.000 30.72696 ? 51  LEU C CB  1 
ATOM   2063 C CG  . LEU C 1 52  ? -34.20893 48.01226 41.32037  1.000 34.05458 ? 51  LEU C CG  1 
ATOM   2064 C CD1 . LEU C 1 52  ? -35.27220 49.10077 41.22477  1.000 33.05031 ? 51  LEU C CD1 1 
ATOM   2065 C CD2 . LEU C 1 52  ? -33.96478 47.64701 42.77473  1.000 32.46354 ? 51  LEU C CD2 1 
ATOM   2066 N N   . ILE C 1 53  ? -34.08482 44.14932 38.65268  1.000 29.30383 ? 52  ILE C N   1 
ATOM   2067 C CA  . ILE C 1 53  ? -34.67437 42.93613 38.07911  1.000 31.79869 ? 52  ILE C CA  1 
ATOM   2068 C C   . ILE C 1 53  ? -33.69665 41.77880 37.98175  1.000 27.77258 ? 52  ILE C C   1 
ATOM   2069 O O   . ILE C 1 53  ? -34.12773 40.64571 37.71876  1.000 30.16202 ? 52  ILE C O   1 
ATOM   2070 C CB  . ILE C 1 53  ? -35.24414 43.14352 36.65700  1.000 31.67579 ? 52  ILE C CB  1 
ATOM   2071 C CG1 . ILE C 1 53  ? -34.14424 43.52646 35.67264  1.000 31.62718 ? 52  ILE C CG1 1 
ATOM   2072 C CG2 . ILE C 1 53  ? -36.32437 44.19531 36.64915  1.000 31.74588 ? 52  ILE C CG2 1 
ATOM   2073 C CD1 . ILE C 1 53  ? -34.64307 43.57609 34.24655  1.000 33.52456 ? 52  ILE C CD1 1 
ATOM   2074 N N   . HIS C 1 54  ? -32.40272 42.02358 38.17724  1.000 32.00967 ? 53  HIS C N   1 
ATOM   2075 C CA  . HIS C 1 54  ? -31.38028 41.04825 37.82080  1.000 30.19397 ? 53  HIS C CA  1 
ATOM   2076 C C   . HIS C 1 54  ? -31.64204 39.68802 38.45495  1.000 32.50957 ? 53  HIS C C   1 
ATOM   2077 O O   . HIS C 1 54  ? -31.85581 39.58497 39.66739  1.000 31.08115 ? 53  HIS C O   1 
ATOM   2078 C CB  . HIS C 1 54  ? -30.00428 41.54029 38.24602  1.000 31.91656 ? 53  HIS C CB  1 
ATOM   2079 C CG  . HIS C 1 54  ? -28.92866 40.53228 38.00308  1.000 35.56599 ? 53  HIS C CG  1 
ATOM   2080 N ND1 . HIS C 1 54  ? -28.68034 40.00750 36.75071  1.000 32.81778 ? 53  HIS C ND1 1 
ATOM   2081 C CD2 . HIS C 1 54  ? -28.07452 39.91300 38.85015  1.000 31.21468 ? 53  HIS C CD2 1 
ATOM   2082 C CE1 . HIS C 1 54  ? -27.69640 39.13061 36.83472  1.000 35.73842 ? 53  HIS C CE1 1 
ATOM   2083 N NE2 . HIS C 1 54  ? -27.31689 39.04892 38.09866  1.000 34.40805 ? 53  HIS C NE2 1 
ATOM   2084 N N   . PHE C 1 55  ? -31.60418 38.64082 37.62996  1.000 25.92658 ? 54  PHE C N   1 
ATOM   2085 C CA  . PHE C 1 55  ? -31.81242 37.26834 38.08330  1.000 27.95992 ? 54  PHE C CA  1 
ATOM   2086 C C   . PHE C 1 55  ? -30.46686 36.61363 38.39602  1.000 33.14713 ? 54  PHE C C   1 
ATOM   2087 O O   . PHE C 1 55  ? -29.58921 36.53995 37.52842  1.000 30.57375 ? 54  PHE C O   1 
ATOM   2088 C CB  . PHE C 1 55  ? -32.56667 36.45828 37.02587  1.000 27.78285 ? 54  PHE C CB  1 
ATOM   2089 C CG  . PHE C 1 55  ? -33.08160 35.13381 37.52932  1.000 30.68989 ? 54  PHE C CG  1 
ATOM   2090 C CD1 . PHE C 1 55  ? -34.35430 35.03046 38.08177  1.000 27.15049 ? 54  PHE C CD1 1 
ATOM   2091 C CD2 . PHE C 1 55  ? -32.28620 33.99553 37.47617  1.000 28.68493 ? 54  PHE C CD2 1 
ATOM   2092 C CE1 . PHE C 1 55  ? -34.82869 33.81439 38.56563  1.000 26.02685 ? 54  PHE C CE1 1 
ATOM   2093 C CE2 . PHE C 1 55  ? -32.75557 32.77185 37.95545  1.000 32.15191 ? 54  PHE C CE2 1 
ATOM   2094 C CZ  . PHE C 1 55  ? -34.03166 32.68212 38.50280  1.000 26.86634 ? 54  PHE C CZ  1 
ATOM   2095 N N   . GLN C 1 56  ? -30.31739 36.11246 39.62399  1.000 34.38092 ? 55  GLN C N   1 
ATOM   2096 C CA  . GLN C 1 56  ? -29.05574 35.54181 40.09029  1.000 38.13695 ? 55  GLN C CA  1 
ATOM   2097 C C   . GLN C 1 56  ? -29.01769 34.03484 39.85138  1.000 41.48065 ? 55  GLN C C   1 
ATOM   2098 O O   . GLN C 1 56  ? -29.85122 33.28524 40.38599  1.000 39.54436 ? 55  GLN C O   1 
ATOM   2099 C CB  . GLN C 1 56  ? -28.82948 35.84743 41.57001  1.000 36.67965 ? 55  GLN C CB  1 
ATOM   2100 C CG  . GLN C 1 56  ? -28.31083 37.24675 41.81755  1.000 41.07888 ? 55  GLN C CG  1 
ATOM   2101 C CD  . GLN C 1 56  ? -28.41248 37.66336 43.27368  1.000 48.17015 ? 55  GLN C CD  1 
ATOM   2102 O OE1 . GLN C 1 56  ? -27.40134 37.89995 43.92378  1.000 50.97427 ? 55  GLN C OE1 1 
ATOM   2103 N NE2 . GLN C 1 56  ? -29.64172 37.78048 43.78530  1.000 50.87276 ? 55  GLN C NE2 1 
ATOM   2104 N N   . SER C 1 57  ? -28.01947 33.60046 39.07559  1.000 40.84217 ? 56  SER C N   1 
ATOM   2105 C CA  . SER C 1 57  ? -27.88004 32.20281 38.65987  1.000 47.00229 ? 56  SER C CA  1 
ATOM   2106 C C   . SER C 1 57  ? -27.59936 31.24936 39.81813  1.000 41.24393 ? 56  SER C C   1 
ATOM   2107 O O   . SER C 1 57  ? -27.86886 30.05096 39.69399  1.000 44.58996 ? 56  SER C O   1 
ATOM   2108 C CB  . SER C 1 57  ? -26.76774 32.07671 37.61006  1.000 48.40102 ? 56  SER C CB  1 
ATOM   2109 O OG  . SER C 1 57  ? -25.50003 32.43120 38.15688  1.000 52.33232 ? 56  SER C OG  1 
ATOM   2110 N N   . SER C 1 58  ? -27.04545 31.73418 40.91595  1.000 38.13073 ? 57  SER C N   1 
ATOM   2111 C CA  . SER C 1 58  ? -26.95599 30.96294 42.14316  1.000 44.55586 ? 57  SER C CA  1 
ATOM   2112 C C   . SER C 1 58  ? -28.25087 31.14324 42.93439  1.000 41.78073 ? 57  SER C C   1 
ATOM   2113 O O   . SER C 1 58  ? -28.92228 32.16975 42.84089  1.000 48.65979 ? 57  SER C O   1 
ATOM   2114 C CB  . SER C 1 58  ? -25.74652 31.42555 42.96378  1.000 47.24564 ? 57  SER C CB  1 
ATOM   2115 O OG  . SER C 1 58  ? -25.75101 32.84721 43.07874  1.000 49.58073 ? 57  SER C OG  1 
ATOM   2116 N N   . GLY C 1 59  ? -28.60738 30.13664 43.70549  1.000 42.38305 ? 58  GLY C N   1 
ATOM   2117 C CA  . GLY C 1 59  ? -29.86414 30.17882 44.42669  1.000 31.95423 ? 58  GLY C CA  1 
ATOM   2118 C C   . GLY C 1 59  ? -31.04529 30.49165 43.52021  1.000 33.90593 ? 58  GLY C C   1 
ATOM   2119 O O   . GLY C 1 59  ? -31.71701 31.52143 43.68964  1.000 29.59484 ? 58  GLY C O   1 
ATOM   2120 N N   . ILE C 1 60  ? -31.30986 29.59946 42.55495  1.000 29.38717 ? 59  ILE C N   1 
ATOM   2121 C CA  . ILE C 1 60  ? -32.39571 29.82357 41.59752  1.000 28.07446 ? 59  ILE C CA  1 
ATOM   2122 C C   . ILE C 1 60  ? -33.74206 29.85427 42.30093  1.000 26.95009 ? 59  ILE C C   1 
ATOM   2123 O O   . ILE C 1 60  ? -34.60533 30.68704 41.98112  1.000 25.58141 ? 59  ILE C O   1 
ATOM   2124 C CB  . ILE C 1 60  ? -32.36622 28.76618 40.47198  1.000 28.15857 ? 59  ILE C CB  1 
ATOM   2125 C CG1 . ILE C 1 60  ? -31.09372 28.93761 39.61126  1.000 29.88286 ? 59  ILE C CG1 1 
ATOM   2126 C CG2 . ILE C 1 60  ? -33.62244 28.83594 39.65499  1.000 25.69232 ? 59  ILE C CG2 1 
ATOM   2127 C CD1 . ILE C 1 60  ? -30.82421 27.76785 38.66123  1.000 29.49799 ? 59  ILE C CD1 1 
ATOM   2128 N N   . SER C 1 61  ? -33.96420 28.93988 43.25860  1.000 24.73888 ? 60  SER C N   1 
ATOM   2129 C CA  . SER C 1 61  ? -35.24214 28.92906 43.96779  1.000 26.56282 ? 60  SER C CA  1 
ATOM   2130 C C   . SER C 1 61  ? -35.50374 30.27670 44.63081  1.000 26.25399 ? 60  SER C C   1 
ATOM   2131 O O   . SER C 1 61  ? -36.56003 30.88558 44.42890  1.000 28.99792 ? 60  SER C O   1 
ATOM   2132 C CB  . SER C 1 61  ? -35.28759 27.79796 44.99581  1.000 24.81448 ? 60  SER C CB  1 
ATOM   2133 O OG  . SER C 1 61  ? -35.25680 26.54458 44.34272  1.000 25.40757 ? 60  SER C OG  1 
ATOM   2134 N N   . TYR C 1 62  ? -34.53210 30.77820 45.40197  1.000 24.24146 ? 61  TYR C N   1 
ATOM   2135 C CA  . TYR C 1 62  ? -34.74268 32.05748 46.06735  1.000 24.43477 ? 61  TYR C CA  1 
ATOM   2136 C C   . TYR C 1 62  ? -34.85104 33.19093 45.05499  1.000 25.17765 ? 61  TYR C C   1 
ATOM   2137 O O   . TYR C 1 62  ? -35.63400 34.12867 45.25042  1.000 23.66260 ? 61  TYR C O   1 
ATOM   2138 C CB  . TYR C 1 62  ? -33.62711 32.34575 47.07627  1.000 24.52774 ? 61  TYR C CB  1 
ATOM   2139 C CG  . TYR C 1 62  ? -33.88848 33.65769 47.78127  1.000 27.67707 ? 61  TYR C CG  1 
ATOM   2140 C CD1 . TYR C 1 62  ? -35.07389 33.84912 48.48018  1.000 25.10347 ? 61  TYR C CD1 1 
ATOM   2141 C CD2 . TYR C 1 62  ? -32.99041 34.71917 47.70330  1.000 27.77983 ? 61  TYR C CD2 1 
ATOM   2142 C CE1 . TYR C 1 62  ? -35.35360 35.04083 49.11574  1.000 29.11855 ? 61  TYR C CE1 1 
ATOM   2143 C CE2 . TYR C 1 62  ? -33.25492 35.93073 48.35269  1.000 29.36275 ? 61  TYR C CE2 1 
ATOM   2144 C CZ  . TYR C 1 62  ? -34.44793 36.07721 49.05799  1.000 30.23953 ? 61  TYR C CZ  1 
ATOM   2145 O OH  . TYR C 1 62  ? -34.77622 37.25245 49.70271  1.000 31.81224 ? 61  TYR C OH  1 
ATOM   2146 N N   . SER C 1 63  ? -34.08148 33.12206 43.96420  1.000 25.68902 ? 62  SER C N   1 
ATOM   2147 C CA  . SER C 1 63  ? -34.19576 34.13662 42.91669  1.000 27.37364 ? 62  SER C CA  1 
ATOM   2148 C C   . SER C 1 63  ? -35.60481 34.17427 42.33760  1.000 27.72554 ? 62  SER C C   1 
ATOM   2149 O O   . SER C 1 63  ? -36.14300 35.25628 42.06973  1.000 26.68589 ? 62  SER C O   1 
ATOM   2150 C CB  . SER C 1 63  ? -33.17055 33.87503 41.80913  1.000 28.78705 ? 62  SER C CB  1 
ATOM   2151 O OG  . SER C 1 63  ? -31.85600 34.14450 42.25431  1.000 31.26490 ? 62  SER C OG  1 
ATOM   2152 N N   . LEU C 1 64  ? -36.21335 33.00346 42.13222  1.000 22.93996 ? 63  LEU C N   1 
ATOM   2153 C CA  . LEU C 1 64  ? -37.58343 32.93588 41.62981  1.000 25.91826 ? 63  LEU C CA  1 
ATOM   2154 C C   . LEU C 1 64  ? -38.57297 33.45398 42.66128  1.000 26.17745 ? 63  LEU C C   1 
ATOM   2155 O O   . LEU C 1 64  ? -39.48730 34.22405 42.33418  1.000 23.57331 ? 63  LEU C O   1 
ATOM   2156 C CB  . LEU C 1 64  ? -37.93414 31.49478 41.24701  1.000 22.93936 ? 63  LEU C CB  1 
ATOM   2157 C CG  . LEU C 1 64  ? -37.27921 30.96887 39.97176  1.000 27.50098 ? 63  LEU C CG  1 
ATOM   2158 C CD1 . LEU C 1 64  ? -37.52173 29.45958 39.78743  1.000 22.80776 ? 63  LEU C CD1 1 
ATOM   2159 C CD2 . LEU C 1 64  ? -37.78874 31.76188 38.77846  1.000 23.12725 ? 63  LEU C CD2 1 
ATOM   2160 N N   . GLU C 1 65  ? -38.40909 33.02482 43.91365  1.000 24.34063 ? 64  GLU C N   1 
ATOM   2161 C CA  . GLU C 1 65  ? -39.32612 33.41132 44.97407  1.000 23.46826 ? 64  GLU C CA  1 
ATOM   2162 C C   . GLU C 1 65  ? -39.25542 34.89798 45.29299  1.000 24.60171 ? 64  GLU C C   1 
ATOM   2163 O O   . GLU C 1 65  ? -40.26140 35.48960 45.69149  1.000 26.81298 ? 64  GLU C O   1 
ATOM   2164 C CB  . GLU C 1 65  ? -39.02825 32.60490 46.23481  1.000 25.59354 ? 64  GLU C CB  1 
ATOM   2165 C CG  . GLU C 1 65  ? -40.17171 32.65274 47.24246  1.000 26.84714 ? 64  GLU C CG  1 
ATOM   2166 C CD  . GLU C 1 65  ? -40.06697 31.54824 48.25643  1.000 28.10637 ? 64  GLU C CD  1 
ATOM   2167 O OE1 . GLU C 1 65  ? -39.40651 31.76873 49.30167  1.000 25.65140 ? 64  GLU C OE1 1 
ATOM   2168 O OE2 . GLU C 1 65  ? -40.61532 30.45348 47.98794  1.000 23.73501 ? 64  GLU C OE2 1 
ATOM   2169 N N   . SER C 1 66  ? -38.08899 35.51418 45.13857  1.000 23.51206 ? 65  SER C N   1 
ATOM   2170 C CA  . SER C 1 66  ? -37.88467 36.90566 45.51884  1.000 24.61920 ? 65  SER C CA  1 
ATOM   2171 C C   . SER C 1 66  ? -37.90310 37.87450 44.33708  1.000 30.76172 ? 65  SER C C   1 
ATOM   2172 O O   . SER C 1 66  ? -37.84059 39.09125 44.55666  1.000 26.37387 ? 65  SER C O   1 
ATOM   2173 C CB  . SER C 1 66  ? -36.56080 37.03528 46.27446  1.000 25.48875 ? 65  SER C CB  1 
ATOM   2174 O OG  . SER C 1 66  ? -35.47252 36.89080 45.37870  1.000 26.59856 ? 65  SER C OG  1 
ATOM   2175 N N   . SER C 1 67  ? -37.98835 37.36811 43.10170  1.000 25.10869 ? 66  SER C N   1 
ATOM   2176 C CA  . SER C 1 67  ? -37.92940 38.22303 41.92755  1.000 23.17055 ? 66  SER C CA  1 
ATOM   2177 C C   . SER C 1 67  ? -38.96916 39.33408 42.01321  1.000 25.08587 ? 66  SER C C   1 
ATOM   2178 O O   . SER C 1 67  ? -40.12033 39.08218 42.39411  1.000 25.03705 ? 66  SER C O   1 
ATOM   2179 C CB  . SER C 1 67  ? -38.17583 37.41330 40.65250  1.000 25.30072 ? 66  SER C CB  1 
ATOM   2180 O OG  . SER C 1 67  ? -38.24315 38.28243 39.52420  1.000 23.17959 ? 66  SER C OG  1 
ATOM   2181 N N   . PRO C 1 68  ? -38.61330 40.56485 41.64405  1.000 25.16913 ? 67  PRO C N   1 
ATOM   2182 C CA  . PRO C 1 68  ? -39.63133 41.62176 41.55247  1.000 29.12627 ? 67  PRO C CA  1 
ATOM   2183 C C   . PRO C 1 68  ? -40.68174 41.34669 40.49551  1.000 26.60707 ? 67  PRO C C   1 
ATOM   2184 O O   . PRO C 1 68  ? -41.72811 42.00687 40.51250  1.000 24.07605 ? 67  PRO C O   1 
ATOM   2185 C CB  . PRO C 1 68  ? -38.82545 42.88525 41.21016  1.000 26.70785 ? 67  PRO C CB  1 
ATOM   2186 C CG  . PRO C 1 68  ? -37.50251 42.41469 40.77091  1.000 30.23217 ? 67  PRO C CG  1 
ATOM   2187 C CD  . PRO C 1 68  ? -37.26927 41.02968 41.26928  1.000 26.00323 ? 67  PRO C CD  1 
ATOM   2188 N N   . LEU C 1 69  ? -40.44211 40.41136 39.56414  1.000 23.76717 ? 68  LEU C N   1 
ATOM   2189 C CA  . LEU C 1 69  ? -41.48893 40.08058 38.59631  1.000 26.46821 ? 68  LEU C CA  1 
ATOM   2190 C C   . LEU C 1 69  ? -42.68571 39.41056 39.25956  1.000 26.53486 ? 68  LEU C C   1 
ATOM   2191 O O   . LEU C 1 69  ? -43.71090 39.22146 38.59938  1.000 25.83992 ? 68  LEU C O   1 
ATOM   2192 C CB  . LEU C 1 69  ? -40.93664 39.18346 37.47252  1.000 24.61040 ? 68  LEU C CB  1 
ATOM   2193 C CG  . LEU C 1 69  ? -40.34998 39.90814 36.25479  1.000 25.65267 ? 68  LEU C CG  1 
ATOM   2194 C CD1 . LEU C 1 69  ? -39.26217 40.87305 36.67969  1.000 22.44517 ? 68  LEU C CD1 1 
ATOM   2195 C CD2 . LEU C 1 69  ? -39.81366 38.92117 35.18073  1.000 27.47391 ? 68  LEU C CD2 1 
ATOM   2196 N N   . ASN C 1 70  ? -42.56745 39.03932 40.53896  1.000 22.19399 ? 69  ASN C N   1 
ATOM   2197 C CA  . ASN C 1 70  ? -43.70078 38.58251 41.33420  1.000 26.45490 ? 69  ASN C CA  1 
ATOM   2198 C C   . ASN C 1 70  ? -44.63449 39.71952 41.72313  1.000 27.57415 ? 69  ASN C C   1 
ATOM   2199 O O   . ASN C 1 70  ? -45.77069 39.45953 42.14159  1.000 25.81422 ? 69  ASN C O   1 
ATOM   2200 C CB  . ASN C 1 70  ? -43.20462 37.92230 42.62350  1.000 21.51790 ? 69  ASN C CB  1 
ATOM   2201 C CG  . ASN C 1 70  ? -42.60412 36.55092 42.39155  1.000 26.98041 ? 69  ASN C CG  1 
ATOM   2202 O OD1 . ASN C 1 70  ? -43.30144 35.61256 42.00201  1.000 23.20669 ? 69  ASN C OD1 1 
ATOM   2203 N ND2 . ASN C 1 70  ? -41.29339 36.42834 42.62472  1.000 23.48670 ? 69  ASN C ND2 1 
ATOM   2204 N N   . SER C 1 71  ? -44.17837 40.96597 41.62533  1.000 24.28671 ? 70  SER C N   1 
ATOM   2205 C CA  . SER C 1 71  ? -44.86416 42.06415 42.29643  1.000 26.00187 ? 70  SER C CA  1 
ATOM   2206 C C   . SER C 1 71  ? -45.63190 42.89802 41.28340  1.000 23.14394 ? 70  SER C C   1 
ATOM   2207 O O   . SER C 1 71  ? -45.01481 43.52852 40.41326  1.000 24.29442 ? 70  SER C O   1 
ATOM   2208 C CB  . SER C 1 71  ? -43.86317 42.93132 43.06674  1.000 24.76754 ? 70  SER C CB  1 
ATOM   2209 O OG  . SER C 1 71  ? -44.38592 44.22938 43.32905  1.000 24.65675 ? 70  SER C OG  1 
ATOM   2210 N N   . PRO C 1 72  ? -46.96682 42.90272 41.33476  1.000 25.73131 ? 71  PRO C N   1 
ATOM   2211 C CA  . PRO C 1 72  ? -47.73102 43.81554 40.46401  1.000 24.75184 ? 71  PRO C CA  1 
ATOM   2212 C C   . PRO C 1 72  ? -47.36005 45.27688 40.65467  1.000 24.60392 ? 71  PRO C C   1 
ATOM   2213 O O   . PRO C 1 72  ? -47.33806 46.03293 39.67711  1.000 24.05072 ? 71  PRO C O   1 
ATOM   2214 C CB  . PRO C 1 72  ? -49.19345 43.54711 40.85763  1.000 26.91849 ? 71  PRO C CB  1 
ATOM   2215 C CG  . PRO C 1 72  ? -49.18013 42.23929 41.58996  1.000 28.76357 ? 71  PRO C CG  1 
ATOM   2216 C CD  . PRO C 1 72  ? -47.82456 42.07507 42.20152  1.000 25.66739 ? 71  PRO C CD  1 
ATOM   2217 N N   . ILE C 1 73  ? -47.05643 45.70200 41.88329  1.000 23.75557 ? 72  ILE C N   1 
ATOM   2218 C CA  . ILE C 1 73  ? -46.65778 47.09114 42.08393  1.000 23.58921 ? 72  ILE C CA  1 
ATOM   2219 C C   . ILE C 1 73  ? -45.39805 47.39043 41.28880  1.000 26.21079 ? 72  ILE C C   1 
ATOM   2220 O O   . ILE C 1 73  ? -45.34303 48.36410 40.52974  1.000 24.49737 ? 72  ILE C O   1 
ATOM   2221 C CB  . ILE C 1 73  ? -46.45766 47.40254 43.57285  1.000 24.11588 ? 72  ILE C CB  1 
ATOM   2222 C CG1 . ILE C 1 73  ? -47.77537 47.21595 44.34494  1.000 26.88541 ? 72  ILE C CG1 1 
ATOM   2223 C CG2 . ILE C 1 73  ? -45.82767 48.81491 43.71965  1.000 21.58473 ? 72  ILE C CG2 1 
ATOM   2224 C CD1 . ILE C 1 73  ? -47.67316 47.45680 45.84895  1.000 24.59610 ? 72  ILE C CD1 1 
ATOM   2225 N N   . PHE C 1 74  ? -44.37114 46.54500 41.43733  1.000 22.61263 ? 73  PHE C N   1 
ATOM   2226 C CA  . PHE C 1 74  ? -43.14956 46.73506 40.66129  1.000 24.13452 ? 73  PHE C CA  1 
ATOM   2227 C C   . PHE C 1 74  ? -43.44330 46.78469 39.16730  1.000 27.58915 ? 73  PHE C C   1 
ATOM   2228 O O   . PHE C 1 74  ? -42.91487 47.64594 38.44807  1.000 27.69954 ? 73  PHE C O   1 
ATOM   2229 C CB  . PHE C 1 74  ? -42.14976 45.61778 40.96350  1.000 27.70713 ? 73  PHE C CB  1 
ATOM   2230 C CG  . PHE C 1 74  ? -40.83516 45.76583 40.24480  1.000 24.67897 ? 73  PHE C CG  1 
ATOM   2231 C CD1 . PHE C 1 74  ? -39.80907 46.50723 40.80716  1.000 30.19427 ? 73  PHE C CD1 1 
ATOM   2232 C CD2 . PHE C 1 74  ? -40.63062 45.16631 39.01019  1.000 29.92684 ? 73  PHE C CD2 1 
ATOM   2233 C CE1 . PHE C 1 74  ? -38.59250 46.64650 40.15637  1.000 33.83542 ? 73  PHE C CE1 1 
ATOM   2234 C CE2 . PHE C 1 74  ? -39.41958 45.29910 38.34127  1.000 33.74869 ? 73  PHE C CE2 1 
ATOM   2235 C CZ  . PHE C 1 74  ? -38.39415 46.04071 38.91957  1.000 32.75100 ? 73  PHE C CZ  1 
ATOM   2236 N N   . LEU C 1 75  ? -44.29261 45.87523 38.68040  1.000 23.82631 ? 74  LEU C N   1 
ATOM   2237 C CA  . LEU C 1 75  ? -44.47580 45.75108 37.23912  1.000 26.57467 ? 74  LEU C CA  1 
ATOM   2238 C C   . LEU C 1 75  ? -45.20933 46.94416 36.63625  1.000 28.13455 ? 74  LEU C C   1 
ATOM   2239 O O   . LEU C 1 75  ? -45.13089 47.13708 35.41941  1.000 26.92289 ? 74  LEU C O   1 
ATOM   2240 C CB  . LEU C 1 75  ? -45.21874 44.45123 36.90635  1.000 24.19363 ? 74  LEU C CB  1 
ATOM   2241 C CG  . LEU C 1 75  ? -44.41301 43.16105 37.08190  1.000 26.51722 ? 74  LEU C CG  1 
ATOM   2242 C CD1 . LEU C 1 75  ? -45.32402 41.93187 37.07500  1.000 22.69381 ? 74  LEU C CD1 1 
ATOM   2243 C CD2 . LEU C 1 75  ? -43.32102 43.03725 35.99600  1.000 26.36970 ? 74  LEU C CD2 1 
ATOM   2244 N N   . ARG C 1 76  ? -45.90884 47.74961 37.45097  1.000 25.94426 ? 75  ARG C N   1 
ATOM   2245 C CA  . ARG C 1 76  ? -46.57334 48.94019 36.92621  1.000 32.06954 ? 75  ARG C CA  1 
ATOM   2246 C C   . ARG C 1 76  ? -45.60156 49.84438 36.18383  1.000 30.08712 ? 75  ARG C C   1 
ATOM   2247 O O   . ARG C 1 76  ? -46.01229 50.58986 35.28930  1.000 31.17123 ? 75  ARG C O   1 
ATOM   2248 C CB  . ARG C 1 76  ? -47.23605 49.75194 38.04890  1.000 28.91725 ? 75  ARG C CB  1 
ATOM   2249 C CG  . ARG C 1 76  ? -48.56243 49.21351 38.56338  1.000 37.02655 ? 75  ARG C CG  1 
ATOM   2250 C CD  . ARG C 1 76  ? -49.64930 48.98430 37.46863  1.000 35.99627 ? 75  ARG C CD  1 
ATOM   2251 N NE  . ARG C 1 76  ? -49.88547 50.13058 36.59291  1.000 32.23335 ? 75  ARG C NE  1 
ATOM   2252 C CZ  . ARG C 1 76  ? -50.81261 50.15608 35.63971  1.000 32.72215 ? 75  ARG C CZ  1 
ATOM   2253 N NH1 . ARG C 1 76  ? -51.63058 49.13458 35.44322  1.000 26.24023 ? 75  ARG C NH1 1 
ATOM   2254 N NH2 . ARG C 1 76  ? -50.91397 51.22905 34.85543  1.000 30.24209 ? 75  ARG C NH2 1 
ATOM   2255 N N   . ARG C 1 77  ? -44.31797 49.81142 36.55079  1.000 26.85475 ? 76  ARG C N   1 
ATOM   2256 C CA  . ARG C 1 77  ? -43.34851 50.69000 35.90756  1.000 31.49862 ? 76  ARG C CA  1 
ATOM   2257 C C   . ARG C 1 77  ? -43.13182 50.32887 34.44088  1.000 33.88279 ? 76  ARG C C   1 
ATOM   2258 O O   . ARG C 1 77  ? -42.64059 51.16736 33.67661  1.000 34.51744 ? 76  ARG C O   1 
ATOM   2259 C CB  . ARG C 1 77  ? -42.02496 50.66476 36.67861  1.000 30.03160 ? 76  ARG C CB  1 
ATOM   2260 C CG  . ARG C 1 77  ? -41.14173 49.46851 36.39486  1.000 30.78178 ? 76  ARG C CG  1 
ATOM   2261 C CD  . ARG C 1 77  ? -40.03910 49.37474 37.45570  1.000 30.09450 ? 76  ARG C CD  1 
ATOM   2262 N NE  . ARG C 1 77  ? -40.58639 49.49480 38.80423  1.000 31.71395 ? 76  ARG C NE  1 
ATOM   2263 C CZ  . ARG C 1 77  ? -39.88429 49.82454 39.88046  1.000 34.75760 ? 76  ARG C CZ  1 
ATOM   2264 N NH1 . ARG C 1 77  ? -38.58485 50.08823 39.80989  1.000 31.25770 ? 76  ARG C NH1 1 
ATOM   2265 N NH2 . ARG C 1 77  ? -40.50146 49.90046 41.05768  1.000 28.88068 ? 76  ARG C NH2 1 
ATOM   2266 N N   . PHE C 1 78  ? -43.51104 49.11507 34.02747  1.000 31.42196 ? 77  PHE C N   1 
ATOM   2267 C CA  . PHE C 1 78  ? -43.46873 48.70552 32.62809  1.000 32.01959 ? 77  PHE C CA  1 
ATOM   2268 C C   . PHE C 1 78  ? -44.82144 48.80656 31.93951  1.000 31.11129 ? 77  PHE C C   1 
ATOM   2269 O O   . PHE C 1 78  ? -44.93775 48.38941 30.78444  1.000 31.54748 ? 77  PHE C O   1 
ATOM   2270 C CB  . PHE C 1 78  ? -42.96225 47.26443 32.51028  1.000 27.73879 ? 77  PHE C CB  1 
ATOM   2271 C CG  . PHE C 1 78  ? -41.64846 47.02894 33.18730  1.000 30.91717 ? 77  PHE C CG  1 
ATOM   2272 C CD1 . PHE C 1 78  ? -40.46952 47.50395 32.63310  1.000 30.60986 ? 77  PHE C CD1 1 
ATOM   2273 C CD2 . PHE C 1 78  ? -41.58604 46.33362 34.37902  1.000 30.30513 ? 77  PHE C CD2 1 
ATOM   2274 C CE1 . PHE C 1 78  ? -39.25708 47.28771 33.26536  1.000 32.45038 ? 77  PHE C CE1 1 
ATOM   2275 C CE2 . PHE C 1 78  ? -40.38282 46.12327 35.00694  1.000 30.30654 ? 77  PHE C CE2 1 
ATOM   2276 C CZ  . PHE C 1 78  ? -39.21566 46.60527 34.45197  1.000 27.71799 ? 77  PHE C CZ  1 
ATOM   2277 N N   . SER C 1 79  ? -45.84892 49.33551 32.62108  1.000 28.70603 ? 78  SER C N   1 
ATOM   2278 C CA  . SER C 1 79  ? -47.21407 49.25076 32.09791  1.000 28.93677 ? 78  SER C CA  1 
ATOM   2279 C C   . SER C 1 79  ? -47.33045 49.94016 30.74194  1.000 29.12355 ? 78  SER C C   1 
ATOM   2280 O O   . SER C 1 79  ? -48.05362 49.47435 29.85363  1.000 29.86057 ? 78  SER C O   1 
ATOM   2281 C CB  . SER C 1 79  ? -48.21062 49.85946 33.10232  1.000 32.56344 ? 78  SER C CB  1 
ATOM   2282 O OG  . SER C 1 79  ? -48.06273 51.27313 33.18495  1.000 36.46751 ? 78  SER C OG  1 
ATOM   2283 N N   . ALA C 1 80  ? -46.63231 51.05610 30.56469  1.000 33.94539 ? 79  ALA C N   1 
ATOM   2284 C CA  . ALA C 1 80  ? -46.77392 51.86532 29.35924  1.000 34.28135 ? 79  ALA C CA  1 
ATOM   2285 C C   . ALA C 1 80  ? -45.81531 51.46337 28.24351  1.000 36.34608 ? 79  ALA C C   1 
ATOM   2286 O O   . ALA C 1 80  ? -45.85871 52.06749 27.16111  1.000 33.69174 ? 79  ALA C O   1 
ATOM   2287 C CB  . ALA C 1 80  ? -46.57100 53.34496 29.70038  1.000 28.36377 ? 79  ALA C CB  1 
ATOM   2288 N N   . CYS C 1 81  ? -44.98311 50.43535 28.46114  1.000 32.93560 ? 80  CYS C N   1 
ATOM   2289 C CA  . CYS C 1 81  ? -43.94447 50.12028 27.49207  1.000 36.72326 ? 80  CYS C CA  1 
ATOM   2290 C C   . CYS C 1 81  ? -43.62369 48.63244 27.46570  1.000 32.50610 ? 80  CYS C C   1 
ATOM   2291 O O   . CYS C 1 81  ? -42.44976 48.25497 27.41482  1.000 36.27896 ? 80  CYS C O   1 
ATOM   2292 C CB  . CYS C 1 81  ? -42.66364 50.89712 27.79344  1.000 32.45095 ? 80  CYS C CB  1 
ATOM   2293 S SG  . CYS C 1 81  ? -42.06321 50.62294 29.50015  1.000 36.12158 ? 80  CYS C SG  1 
ATOM   2294 N N   . SER C 1 82  ? -44.63682 47.77326 27.49484  1.000 32.73282 ? 81  SER C N   1 
ATOM   2295 C CA  . SER C 1 82  ? -44.41720 46.33342 27.45886  1.000 31.18194 ? 81  SER C CA  1 
ATOM   2296 C C   . SER C 1 82  ? -45.71868 45.65962 27.04397  1.000 30.15152 ? 81  SER C C   1 
ATOM   2297 O O   . SER C 1 82  ? -46.75572 46.30780 26.85533  1.000 32.16115 ? 81  SER C O   1 
ATOM   2298 C CB  . SER C 1 82  ? -43.90382 45.80595 28.81014  1.000 29.52910 ? 81  SER C CB  1 
ATOM   2299 O OG  . SER C 1 82  ? -44.89490 45.91404 29.81655  1.000 31.21816 ? 81  SER C OG  1 
ATOM   2300 N N   . VAL C 1 83  ? -45.65013 44.34086 26.89402  1.000 29.09001 ? 82  VAL C N   1 
ATOM   2301 C CA  . VAL C 1 83  ? -46.80393 43.51803 26.55577  1.000 30.19319 ? 82  VAL C CA  1 
ATOM   2302 C C   . VAL C 1 83  ? -46.85465 42.34937 27.53460  1.000 29.13243 ? 82  VAL C C   1 
ATOM   2303 O O   . VAL C 1 83  ? -45.84489 41.67109 27.75211  1.000 24.14846 ? 82  VAL C O   1 
ATOM   2304 C CB  . VAL C 1 83  ? -46.74294 43.01181 25.09924  1.000 28.85772 ? 82  VAL C CB  1 
ATOM   2305 C CG1 . VAL C 1 83  ? -47.93239 42.12926 24.79626  1.000 28.18298 ? 82  VAL C CG1 1 
ATOM   2306 C CG2 . VAL C 1 83  ? -46.70737 44.19158 24.13023  1.000 30.31306 ? 82  VAL C CG2 1 
ATOM   2307 N N   . GLY C 1 84  ? -48.01540 42.13967 28.14789  1.000 28.75842 ? 83  GLY C N   1 
ATOM   2308 C CA  . GLY C 1 84  ? -48.23696 40.98194 28.99036  1.000 29.52513 ? 83  GLY C CA  1 
ATOM   2309 C C   . GLY C 1 84  ? -47.88944 41.14233 30.45566  1.000 27.70035 ? 83  GLY C C   1 
ATOM   2310 O O   . GLY C 1 84  ? -47.85843 40.13508 31.17655  1.000 25.37458 ? 83  GLY C O   1 
ATOM   2311 N N   . PHE C 1 85  ? -47.64057 42.36895 30.92843  1.000 26.61429 ? 84  PHE C N   1 
ATOM   2312 C CA  . PHE C 1 85  ? -47.24107 42.54215 32.32238  1.000 25.95266 ? 84  PHE C CA  1 
ATOM   2313 C C   . PHE C 1 85  ? -48.33372 42.09729 33.29090  1.000 23.81908 ? 84  PHE C C   1 
ATOM   2314 O O   . PHE C 1 85  ? -48.02688 41.70977 34.42349  1.000 23.10075 ? 84  PHE C O   1 
ATOM   2315 C CB  . PHE C 1 85  ? -46.85445 43.99834 32.59000  1.000 26.57824 ? 84  PHE C CB  1 
ATOM   2316 C CG  . PHE C 1 85  ? -48.02743 44.90773 32.84683  1.000 26.29651 ? 84  PHE C CG  1 
ATOM   2317 C CD1 . PHE C 1 85  ? -48.76060 45.43179 31.79564  1.000 29.58150 ? 84  PHE C CD1 1 
ATOM   2318 C CD2 . PHE C 1 85  ? -48.38220 45.25362 34.14212  1.000 28.33652 ? 84  PHE C CD2 1 
ATOM   2319 C CE1 . PHE C 1 85  ? -49.82905 46.27492 32.03015  1.000 28.47166 ? 84  PHE C CE1 1 
ATOM   2320 C CE2 . PHE C 1 85  ? -49.46601 46.09803 34.38660  1.000 27.42997 ? 84  PHE C CE2 1 
ATOM   2321 C CZ  . PHE C 1 85  ? -50.18316 46.60236 33.33506  1.000 28.42139 ? 84  PHE C CZ  1 
ATOM   2322 N N   . GLU C 1 86  ? -49.60428 42.13749 32.86816  1.000 23.09174 ? 85  GLU C N   1 
ATOM   2323 C CA  . GLU C 1 86  ? -50.69524 41.75776 33.76155  1.000 23.40534 ? 85  GLU C CA  1 
ATOM   2324 C C   . GLU C 1 86  ? -50.60768 40.29642 34.17423  1.000 25.87711 ? 85  GLU C C   1 
ATOM   2325 O O   . GLU C 1 86  ? -51.06908 39.92864 35.26250  1.000 21.27125 ? 85  GLU C O   1 
ATOM   2326 C CB  . GLU C 1 86  ? -52.04458 42.01904 33.09706  1.000 23.78291 ? 85  GLU C CB  1 
ATOM   2327 C CG  . GLU C 1 86  ? -52.33658 43.48869 32.78811  1.000 25.70827 ? 85  GLU C CG  1 
ATOM   2328 C CD  . GLU C 1 86  ? -51.95386 43.87125 31.36820  1.000 30.59753 ? 85  GLU C CD  1 
ATOM   2329 O OE1 . GLU C 1 86  ? -51.05802 43.21223 30.79249  1.000 28.64972 ? 85  GLU C OE1 1 
ATOM   2330 O OE2 . GLU C 1 86  ? -52.55635 44.82362 30.83071  1.000 27.53239 ? 85  GLU C OE2 1 
ATOM   2331 N N   . GLU C 1 87  ? -50.02156 39.45472 33.32230  1.000 23.41735 ? 86  GLU C N   1 
ATOM   2332 C CA  . GLU C 1 87  ? -50.01987 38.01220 33.49705  1.000 25.67424 ? 86  GLU C CA  1 
ATOM   2333 C C   . GLU C 1 87  ? -48.72908 37.48120 34.10643  1.000 23.30566 ? 86  GLU C C   1 
ATOM   2334 O O   . GLU C 1 87  ? -48.63799 36.27890 34.38546  1.000 23.45473 ? 86  GLU C O   1 
ATOM   2335 C CB  . GLU C 1 87  ? -50.24826 37.34188 32.13948  1.000 27.16359 ? 86  GLU C CB  1 
ATOM   2336 C CG  . GLU C 1 87  ? -51.61470 37.59106 31.53798  1.000 26.62846 ? 86  GLU C CG  1 
ATOM   2337 C CD  . GLU C 1 87  ? -52.68006 36.68897 32.11599  1.000 34.50613 ? 86  GLU C CD  1 
ATOM   2338 O OE1 . GLU C 1 87  ? -52.36581 35.84837 33.00543  1.000 35.22332 ? 86  GLU C OE1 1 
ATOM   2339 O OE2 . GLU C 1 87  ? -53.83235 36.78914 31.64117  1.000 35.58533 ? 86  GLU C OE2 1 
ATOM   2340 N N   . ILE C 1 88  ? -47.73485 38.33709 34.30619  1.000 23.72519 ? 87  ILE C N   1 
ATOM   2341 C CA  . ILE C 1 88  ? -46.40306 37.90846 34.72709  1.000 22.92523 ? 87  ILE C CA  1 
ATOM   2342 C C   . ILE C 1 88  ? -46.40085 37.38260 36.16455  1.000 24.17651 ? 87  ILE C C   1 
ATOM   2343 O O   . ILE C 1 88  ? -45.77225 36.34064 36.41151  1.000 21.34429 ? 87  ILE C O   1 
ATOM   2344 C CB  . ILE C 1 88  ? -45.38727 39.04261 34.50405  1.000 25.34677 ? 87  ILE C CB  1 
ATOM   2345 C CG1 . ILE C 1 88  ? -45.06218 39.13437 33.00672  1.000 26.62467 ? 87  ILE C CG1 1 
ATOM   2346 C CG2 . ILE C 1 88  ? -44.09588 38.82765 35.30139  1.000 19.88392 ? 87  ILE C CG2 1 
ATOM   2347 C CD1 . ILE C 1 88  ? -44.37499 37.85948 32.45940  1.000 21.00443 ? 87  ILE C CD1 1 
ATOM   2348 N N   . PRO C 1 89  ? -47.08517 37.99881 37.14343  1.000 22.36558 ? 88  PRO C N   1 
ATOM   2349 C CA  . PRO C 1 89  ? -47.10831 37.35395 38.47266  1.000 23.21841 ? 88  PRO C CA  1 
ATOM   2350 C C   . PRO C 1 89  ? -47.67424 35.94366 38.42927  1.000 21.93456 ? 88  PRO C C   1 
ATOM   2351 O O   . PRO C 1 89  ? -47.12721 35.04039 39.08001  1.000 21.19873 ? 88  PRO C O   1 
ATOM   2352 C CB  . PRO C 1 89  ? -47.96809 38.30706 39.31754  1.000 21.93704 ? 88  PRO C CB  1 
ATOM   2353 C CG  . PRO C 1 89  ? -47.74456 39.64537 38.67935  1.000 22.50875 ? 88  PRO C CG  1 
ATOM   2354 C CD  . PRO C 1 89  ? -47.76852 39.30800 37.18695  1.000 22.57945 ? 88  PRO C CD  1 
ATOM   2355 N N   . THR C 1 90  ? -48.72949 35.72295 37.63867  1.000 21.93232 ? 89  THR C N   1 
ATOM   2356 C CA  . THR C 1 90  ? -49.24359 34.37167 37.43230  1.000 24.95125 ? 89  THR C CA  1 
ATOM   2357 C C   . THR C 1 90  ? -48.17482 33.45875 36.83961  1.000 23.00595 ? 89  THR C C   1 
ATOM   2358 O O   . THR C 1 90  ? -47.99090 32.32103 37.29033  1.000 22.79128 ? 89  THR C O   1 
ATOM   2359 C CB  . THR C 1 90  ? -50.47477 34.41251 36.52287  1.000 24.13123 ? 89  THR C CB  1 
ATOM   2360 O OG1 . THR C 1 90  ? -51.49363 35.19859 37.14679  1.000 26.27487 ? 89  THR C OG1 1 
ATOM   2361 C CG2 . THR C 1 90  ? -51.00091 33.00249 36.25640  1.000 24.64524 ? 89  THR C CG2 1 
ATOM   2362 N N   . ALA C 1 91  ? -47.46225 33.93768 35.81477  1.000 22.96804 ? 90  ALA C N   1 
ATOM   2363 C CA  . ALA C 1 91  ? -46.44218 33.09973 35.19629  1.000 23.15370 ? 90  ALA C CA  1 
ATOM   2364 C C   . ALA C 1 91  ? -45.34464 32.74299 36.19539  1.000 22.26360 ? 90  ALA C C   1 
ATOM   2365 O O   . ALA C 1 91  ? -44.86852 31.60013 36.21740  1.000 23.64774 ? 90  ALA C O   1 
ATOM   2366 C CB  . ALA C 1 91  ? -45.86096 33.79383 33.95917  1.000 22.78270 ? 90  ALA C CB  1 
ATOM   2367 N N   . LEU C 1 92  ? -44.94706 33.69269 37.05618  1.000 21.36183 ? 91  LEU C N   1 
ATOM   2368 C CA  . LEU C 1 92  ? -43.90352 33.37669 38.02625  1.000 23.39118 ? 91  LEU C CA  1 
ATOM   2369 C C   . LEU C 1 92  ? -44.38000 32.34490 39.03292  1.000 24.02017 ? 91  LEU C C   1 
ATOM   2370 O O   . LEU C 1 92  ? -43.60912 31.46172 39.43789  1.000 22.57514 ? 91  LEU C O   1 
ATOM   2371 C CB  . LEU C 1 92  ? -43.42943 34.62855 38.76124  1.000 24.91255 ? 91  LEU C CB  1 
ATOM   2372 C CG  . LEU C 1 92  ? -42.00635 35.00404 38.34932  1.000 22.97807 ? 91  LEU C CG  1 
ATOM   2373 C CD1 . LEU C 1 92  ? -42.00947 35.51055 36.91458  1.000 21.96377 ? 91  LEU C CD1 1 
ATOM   2374 C CD2 . LEU C 1 92  ? -41.42280 36.02144 39.28159  1.000 31.91942 ? 91  LEU C CD2 1 
ATOM   2375 N N   . GLN C 1 93  ? -45.63477 32.47013 39.47804  1.000 22.72417 ? 92  GLN C N   1 
ATOM   2376 C CA  . GLN C 1 93  ? -46.21782 31.45864 40.34964  1.000 26.21490 ? 92  GLN C CA  1 
ATOM   2377 C C   . GLN C 1 93  ? -46.14167 30.08934 39.69651  1.000 26.68729 ? 92  GLN C C   1 
ATOM   2378 O O   . GLN C 1 93  ? -45.75795 29.10500 40.33801  1.000 25.34928 ? 92  GLN C O   1 
ATOM   2379 C CB  . GLN C 1 93  ? -47.66926 31.82945 40.67215  1.000 26.13812 ? 92  GLN C CB  1 
ATOM   2380 C CG  . GLN C 1 93  ? -48.23916 31.17386 41.91506  1.000 38.32678 ? 92  GLN C CG  1 
ATOM   2381 C CD  . GLN C 1 93  ? -47.63455 31.71240 43.19435  1.000 42.94458 ? 92  GLN C CD  1 
ATOM   2382 O OE1 . GLN C 1 93  ? -47.67594 32.91916 43.45820  1.000 48.67730 ? 92  GLN C OE1 1 
ATOM   2383 N NE2 . GLN C 1 93  ? -47.05893 30.81667 43.99918  1.000 45.83404 ? 92  GLN C NE2 1 
ATOM   2384 N N   . ARG C 1 94  ? -46.47622 30.01962 38.40399  1.000 23.90026 ? 93  ARG C N   1 
ATOM   2385 C CA  . ARG C 1 94  ? -46.45774 28.74668 37.69199  1.000 24.39948 ? 93  ARG C CA  1 
ATOM   2386 C C   . ARG C 1 94  ? -45.03561 28.21738 37.56204  1.000 24.25797 ? 93  ARG C C   1 
ATOM   2387 O O   . ARG C 1 94  ? -44.77587 27.03440 37.81665  1.000 24.58245 ? 93  ARG C O   1 
ATOM   2388 C CB  . ARG C 1 94  ? -47.10758 28.92037 36.31621  1.000 25.73481 ? 93  ARG C CB  1 
ATOM   2389 C CG  . ARG C 1 94  ? -47.31533 27.62781 35.54801  1.000 28.31070 ? 93  ARG C CG  1 
ATOM   2390 C CD  . ARG C 1 94  ? -47.78053 27.89407 34.11443  1.000 25.07960 ? 93  ARG C CD  1 
ATOM   2391 N NE  . ARG C 1 94  ? -46.88224 28.80106 33.41329  1.000 26.43507 ? 93  ARG C NE  1 
ATOM   2392 C CZ  . ARG C 1 94  ? -47.20610 30.02402 33.02312  1.000 27.02896 ? 93  ARG C CZ  1 
ATOM   2393 N NH1 . ARG C 1 94  ? -48.42006 30.51423 33.22615  1.000 26.62446 ? 93  ARG C NH1 1 
ATOM   2394 N NH2 . ARG C 1 94  ? -46.28941 30.77581 32.41384  1.000 27.62174 ? 93  ARG C NH2 1 
ATOM   2395 N N   . ILE C 1 95  ? -44.10044 29.08576 37.16404  1.000 24.53990 ? 94  ILE C N   1 
ATOM   2396 C CA  . ILE C 1 95  ? -42.70573 28.67405 37.00402  1.000 22.82934 ? 94  ILE C CA  1 
ATOM   2397 C C   . ILE C 1 95  ? -42.14305 28.20430 38.33959  1.000 25.29536 ? 94  ILE C C   1 
ATOM   2398 O O   . ILE C 1 95  ? -41.44624 27.18413 38.41261  1.000 22.84943 ? 94  ILE C O   1 
ATOM   2399 C CB  . ILE C 1 95  ? -41.87836 29.82759 36.39541  1.000 22.54027 ? 94  ILE C CB  1 
ATOM   2400 C CG1 . ILE C 1 95  ? -42.20958 30.00514 34.90619  1.000 24.56117 ? 94  ILE C CG1 1 
ATOM   2401 C CG2 . ILE C 1 95  ? -40.37842 29.60355 36.56708  1.000 24.42487 ? 94  ILE C CG2 1 
ATOM   2402 C CD1 . ILE C 1 95  ? -41.83857 31.37734 34.35668  1.000 23.20079 ? 94  ILE C CD1 1 
ATOM   2403 N N   . ARG C 1 96  ? -42.48036 28.91106 39.42338  1.000 24.11946 ? 95  ARG C N   1 
ATOM   2404 C CA  . ARG C 1 96  ? -42.00809 28.51340 40.74837  1.000 26.20549 ? 95  ARG C CA  1 
ATOM   2405 C C   . ARG C 1 96  ? -42.52041 27.12922 41.12713  1.000 24.74814 ? 95  ARG C C   1 
ATOM   2406 O O   . ARG C 1 96  ? -41.77027 26.29666 41.64548  1.000 23.48043 ? 95  ARG C O   1 
ATOM   2407 C CB  . ARG C 1 96  ? -42.44086 29.54545 41.78914  1.000 21.36324 ? 95  ARG C CB  1 
ATOM   2408 C CG  . ARG C 1 96  ? -41.47905 30.71471 41.90563  1.000 25.85697 ? 95  ARG C CG  1 
ATOM   2409 C CD  . ARG C 1 96  ? -42.15864 31.93750 42.51320  1.000 25.04149 ? 95  ARG C CD  1 
ATOM   2410 N NE  . ARG C 1 96  ? -42.51206 31.69358 43.90452  1.000 26.10802 ? 95  ARG C NE  1 
ATOM   2411 C CZ  . ARG C 1 96  ? -43.30322 32.47828 44.62104  1.000 32.50370 ? 95  ARG C CZ  1 
ATOM   2412 N NH1 . ARG C 1 96  ? -43.77646 33.61179 44.13018  1.000 30.08646 ? 95  ARG C NH1 1 
ATOM   2413 N NH2 . ARG C 1 96  ? -43.62118 32.11999 45.86383  1.000 31.01138 ? 95  ARG C NH2 1 
ATOM   2414 N N   . SER C 1 97  ? -43.79264 26.85869 40.86743  1.000 24.45057 ? 96  SER C N   1 
ATOM   2415 C CA  . SER C 1 97  ? -44.33399 25.56360 41.23684  1.000 23.83104 ? 96  SER C CA  1 
ATOM   2416 C C   . SER C 1 97  ? -43.70736 24.44346 40.40288  1.000 24.38214 ? 96  SER C C   1 
ATOM   2417 O O   . SER C 1 97  ? -43.47702 23.34253 40.91607  1.000 24.39364 ? 96  SER C O   1 
ATOM   2418 C CB  . SER C 1 97  ? -45.85190 25.58783 41.08990  1.000 22.46750 ? 96  SER C CB  1 
ATOM   2419 O OG  . SER C 1 97  ? -46.20051 25.22724 39.76434  1.000 31.85569 ? 96  SER C OG  1 
ATOM   2420 N N   . VAL C 1 98  ? -43.39749 24.71194 39.12755  1.000 23.76260 ? 97  VAL C N   1 
ATOM   2421 C CA  . VAL C 1 98  ? -42.79528 23.69198 38.26438  1.000 19.81744 ? 97  VAL C CA  1 
ATOM   2422 C C   . VAL C 1 98  ? -41.34898 23.43621 38.66783  1.000 21.24836 ? 97  VAL C C   1 
ATOM   2423 O O   . VAL C 1 98  ? -40.91942 22.28531 38.80271  1.000 22.17246 ? 97  VAL C O   1 
ATOM   2424 C CB  . VAL C 1 98  ? -42.89426 24.10981 36.78371  1.000 23.22946 ? 97  VAL C CB  1 
ATOM   2425 C CG1 . VAL C 1 98  ? -42.02496 23.20743 35.90285  1.000 23.75205 ? 97  VAL C CG1 1 
ATOM   2426 C CG2 . VAL C 1 98  ? -44.34428 24.08647 36.31785  1.000 23.34004 ? 97  VAL C CG2 1 
ATOM   2427 N N   . TYR C 1 99  ? -40.57163 24.50480 38.86865  1.000 23.36208 ? 98  TYR C N   1 
ATOM   2428 C CA  . TYR C 1 99  ? -39.17287 24.33187 39.24862  1.000 22.27785 ? 98  TYR C CA  1 
ATOM   2429 C C   . TYR C 1 99  ? -39.05190 23.66964 40.61935  1.000 24.94898 ? 98  TYR C C   1 
ATOM   2430 O O   . TYR C 1 99  ? -38.27073 22.72650 40.80284  1.000 22.44813 ? 98  TYR C O   1 
ATOM   2431 C CB  . TYR C 1 99  ? -38.45047 25.67910 39.22975  1.000 23.33178 ? 98  TYR C CB  1 
ATOM   2432 C CG  . TYR C 1 99  ? -36.96243 25.50410 39.38653  1.000 25.87198 ? 98  TYR C CG  1 
ATOM   2433 C CD1 . TYR C 1 99  ? -36.19913 24.91959 38.37559  1.000 23.04680 ? 98  TYR C CD1 1 
ATOM   2434 C CD2 . TYR C 1 99  ? -36.32422 25.86737 40.56914  1.000 26.98828 ? 98  TYR C CD2 1 
ATOM   2435 C CE1 . TYR C 1 99  ? -34.82814 24.71800 38.53901  1.000 28.07881 ? 98  TYR C CE1 1 
ATOM   2436 C CE2 . TYR C 1 99  ? -34.95787 25.68542 40.73494  1.000 24.60629 ? 98  TYR C CE2 1 
ATOM   2437 C CZ  . TYR C 1 99  ? -34.21641 25.11051 39.72400  1.000 27.26919 ? 98  TYR C CZ  1 
ATOM   2438 O OH  . TYR C 1 99  ? -32.86481 24.93639 39.91350  1.000 29.02805 ? 98  TYR C OH  1 
ATOM   2439 N N   . THR C 1 100 ? -39.83089 24.14868 41.59609  1.000 22.64503 ? 99  THR C N   1 
ATOM   2440 C CA  . THR C 1 100 ? -39.85317 23.52486 42.91503  1.000 22.15443 ? 99  THR C CA  1 
ATOM   2441 C C   . THR C 1 100 ? -40.14951 22.02977 42.82532  1.000 25.60810 ? 99  THR C C   1 
ATOM   2442 O O   . THR C 1 100 ? -39.47987 21.21325 43.46718  1.000 25.86849 ? 99  THR C O   1 
ATOM   2443 C CB  . THR C 1 100 ? -40.88649 24.21696 43.80180  1.000 21.74016 ? 99  THR C CB  1 
ATOM   2444 O OG1 . THR C 1 100 ? -40.45166 25.54855 44.08872  1.000 22.87186 ? 99  THR C OG1 1 
ATOM   2445 C CG2 . THR C 1 100 ? -41.05417 23.47266 45.09880  1.000 22.75938 ? 99  THR C CG2 1 
ATOM   2446 N N   . ALA C 1 101 ? -41.15631 21.65039 42.03330  1.000 22.87218 ? 100 ALA C N   1 
ATOM   2447 C CA  . ALA C 1 101 ? -41.50027 20.23633 41.92706  1.000 26.12871 ? 100 ALA C CA  1 
ATOM   2448 C C   . ALA C 1 101 ? -40.37485 19.43728 41.27755  1.000 25.89279 ? 100 ALA C C   1 
ATOM   2449 O O   . ALA C 1 101 ? -40.13680 18.28259 41.64398  1.000 25.92217 ? 100 ALA C O   1 
ATOM   2450 C CB  . ALA C 1 101 ? -42.79621 20.06125 41.13931  1.000 23.07765 ? 100 ALA C CB  1 
ATOM   2451 N N   . LYS C 1 102 ? -39.69135 20.02897 40.29672  1.000 23.63478 ? 101 LYS C N   1 
ATOM   2452 C CA  . LYS C 1 102 ? -38.56595 19.35867 39.65672  1.000 26.09758 ? 101 LYS C CA  1 
ATOM   2453 C C   . LYS C 1 102 ? -37.46294 19.05776 40.66831  1.000 26.11564 ? 101 LYS C C   1 
ATOM   2454 O O   . LYS C 1 102 ? -36.92340 17.94443 40.70202  1.000 24.75950 ? 101 LYS C O   1 
ATOM   2455 C CB  . LYS C 1 102 ? -38.04681 20.22682 38.50603  1.000 26.89031 ? 101 LYS C CB  1 
ATOM   2456 C CG  . LYS C 1 102 ? -36.87368 19.64543 37.71759  1.000 28.29002 ? 101 LYS C CG  1 
ATOM   2457 C CD  . LYS C 1 102 ? -36.54260 20.52501 36.50019  1.000 27.64415 ? 101 LYS C CD  1 
ATOM   2458 C CE  . LYS C 1 102 ? -35.59257 19.83145 35.52392  1.000 28.72408 ? 101 LYS C CE  1 
ATOM   2459 N NZ  . LYS C 1 102 ? -35.36766 20.65823 34.29279  1.000 30.46164 ? 101 LYS C NZ  1 
ATOM   2460 N N   . LEU C 1 103 ? -37.14109 20.02596 41.52700  1.000 24.73924 ? 102 LEU C N   1 
ATOM   2461 C CA  . LEU C 1 103 ? -36.13499 19.78957 42.55898  1.000 26.51924 ? 102 LEU C CA  1 
ATOM   2462 C C   . LEU C 1 103 ? -36.61145 18.77650 43.59574  1.000 27.97176 ? 102 LEU C C   1 
ATOM   2463 O O   . LEU C 1 103 ? -35.83238 17.92626 44.03571  1.000 30.23394 ? 102 LEU C O   1 
ATOM   2464 C CB  . LEU C 1 103 ? -35.75518 21.10577 43.23896  1.000 26.33731 ? 102 LEU C CB  1 
ATOM   2465 C CG  . LEU C 1 103 ? -35.02359 22.09672 42.32320  1.000 29.88570 ? 102 LEU C CG  1 
ATOM   2466 C CD1 . LEU C 1 103 ? -34.44250 23.25118 43.11790  1.000 30.20537 ? 102 LEU C CD1 1 
ATOM   2467 C CD2 . LEU C 1 103 ? -33.94191 21.39423 41.50325  1.000 30.72300 ? 102 LEU C CD2 1 
ATOM   2468 N N   . LEU C 1 104 ? -37.87911 18.84227 44.01119  1.000 26.37100 ? 103 LEU C N   1 
ATOM   2469 C CA  . LEU C 1 104 ? -38.30413 17.94210 45.07894  1.000 28.39205 ? 103 LEU C CA  1 
ATOM   2470 C C   . LEU C 1 104 ? -38.57850 16.51894 44.60129  1.000 28.52933 ? 103 LEU C C   1 
ATOM   2471 O O   . LEU C 1 104 ? -38.48376 15.58516 45.40323  1.000 32.43841 ? 103 LEU C O   1 
ATOM   2472 C CB  . LEU C 1 104 ? -39.55603 18.47885 45.77600  1.000 28.07602 ? 103 LEU C CB  1 
ATOM   2473 C CG  . LEU C 1 104 ? -39.49378 19.87575 46.38165  1.000 30.13840 ? 103 LEU C CG  1 
ATOM   2474 C CD1 . LEU C 1 104 ? -40.87309 20.30556 46.86304  1.000 28.22747 ? 103 LEU C CD1 1 
ATOM   2475 C CD2 . LEU C 1 104 ? -38.49389 19.89825 47.51958  1.000 29.20027 ? 103 LEU C CD2 1 
ATOM   2476 N N   . GLU C 1 105 ? -38.93155 16.33057 43.33783  1.000 28.79556 ? 104 GLU C N   1 
ATOM   2477 C CA  . GLU C 1 105 ? -39.25466 15.00514 42.80594  1.000 35.19022 ? 104 GLU C CA  1 
ATOM   2478 C C   . GLU C 1 105 ? -38.12284 13.98049 42.99558  1.000 34.30461 ? 104 GLU C C   1 
ATOM   2479 O O   . GLU C 1 105 ? -36.94548 14.31335 42.81084  1.000 39.60826 ? 104 GLU C O   1 
ATOM   2480 C CB  . GLU C 1 105 ? -39.59956 15.13128 41.32986  1.000 34.55132 ? 104 GLU C CB  1 
ATOM   2481 C CG  . GLU C 1 105 ? -40.10950 13.86279 40.69286  1.000 41.21047 ? 104 GLU C CG  1 
ATOM   2482 C CD  . GLU C 1 105 ? -39.01410 13.10120 39.98225  1.000 45.45065 ? 104 GLU C CD  1 
ATOM   2483 O OE1 . GLU C 1 105 ? -37.86960 13.60466 39.93110  1.000 45.82376 ? 104 GLU C OE1 1 
ATOM   2484 O OE2 . GLU C 1 105 ? -39.30853 12.00722 39.46101  1.000 57.68630 ? 104 GLU C OE2 1 
HETATM 2485 O O   . HOH D 2 .   ? -46.63626 7.83160  -7.74216  1.000 42.52587 ? 201 HOH A O   1 
HETATM 2486 O O   . HOH D 2 .   ? -37.84762 22.66897 -26.63198 1.000 30.48906 ? 202 HOH A O   1 
HETATM 2487 O O   . HOH D 2 .   ? -41.37280 41.92940 -24.02628 1.000 29.75413 ? 203 HOH A O   1 
HETATM 2488 O O   . HOH D 2 .   ? -22.67106 27.04782 -21.17118 1.000 37.20407 ? 204 HOH A O   1 
HETATM 2489 O O   . HOH D 2 .   ? -37.46115 38.00843 -27.36950 1.000 35.16580 ? 205 HOH A O   1 
HETATM 2490 O O   . HOH D 2 .   ? -33.59199 17.70750 -21.40474 1.000 32.48625 ? 206 HOH A O   1 
HETATM 2491 O O   . HOH D 2 .   ? -26.89749 42.35912 -16.07975 1.000 37.93185 ? 207 HOH A O   1 
HETATM 2492 O O   . HOH D 2 .   ? -46.39828 43.90089 -17.98655 1.000 18.96052 ? 208 HOH A O   1 
HETATM 2493 O O   . HOH D 2 .   ? -47.57913 9.19359  -11.46189 1.000 34.22180 ? 209 HOH A O   1 
HETATM 2494 O O   . HOH D 2 .   ? -38.95522 12.71714 -11.99958 1.000 32.51120 ? 210 HOH A O   1 
HETATM 2495 O O   . HOH D 2 .   ? -31.25106 32.21304 -7.40520  1.000 36.00669 ? 211 HOH A O   1 
HETATM 2496 O O   . HOH D 2 .   ? -50.85214 37.72797 -20.28060 1.000 35.79083 ? 212 HOH A O   1 
HETATM 2497 O O   . HOH D 2 .   ? -15.53795 37.21148 -35.31269 1.000 49.31578 ? 213 HOH A O   1 
HETATM 2498 O O   . HOH D 2 .   ? -28.62066 21.11140 -18.57399 1.000 28.35765 ? 214 HOH A O   1 
HETATM 2499 O O   . HOH D 2 .   ? -39.14307 31.98443 -27.26068 1.000 25.71851 ? 215 HOH A O   1 
HETATM 2500 O O   . HOH D 2 .   ? -33.06877 27.75717 -15.28332 1.000 25.91519 ? 216 HOH A O   1 
HETATM 2501 O O   . HOH D 2 .   ? -22.25234 34.07979 -10.26211 1.000 47.06051 ? 217 HOH A O   1 
HETATM 2502 O O   . HOH D 2 .   ? -22.05541 34.66257 -31.51175 1.000 38.20717 ? 218 HOH A O   1 
HETATM 2503 O O   . HOH D 2 .   ? -32.15318 27.41624 -0.49681  1.000 33.33772 ? 219 HOH A O   1 
HETATM 2504 O O   . HOH D 2 .   ? -49.49463 8.33864  -2.75041  1.000 36.34341 ? 220 HOH A O   1 
HETATM 2505 O O   . HOH D 2 .   ? -39.98770 18.58545 -18.60887 1.000 24.25546 ? 221 HOH A O   1 
HETATM 2506 O O   . HOH D 2 .   ? -47.94066 35.05736 -13.38965 1.000 17.95552 ? 222 HOH A O   1 
HETATM 2507 O O   . HOH D 2 .   ? -48.34656 22.91807 -17.33197 1.000 24.15984 ? 223 HOH A O   1 
HETATM 2508 O O   . HOH D 2 .   ? -37.83815 13.31766 -14.02561 1.000 36.73915 ? 224 HOH A O   1 
HETATM 2509 O O   . HOH D 2 .   ? -32.72083 42.99474 -26.07200 1.000 31.86299 ? 225 HOH A O   1 
HETATM 2510 O O   . HOH D 2 .   ? -37.78666 14.23488 -8.26308  1.000 27.12286 ? 226 HOH A O   1 
HETATM 2511 O O   . HOH D 2 .   ? -38.27643 15.89580 -6.27064  1.000 33.87058 ? 227 HOH A O   1 
HETATM 2512 O O   . HOH D 2 .   ? -42.06757 33.46442 -24.15579 1.000 23.67971 ? 228 HOH A O   1 
HETATM 2513 O O   . HOH D 2 .   ? -21.93808 46.92278 -17.24068 1.000 52.00206 ? 229 HOH A O   1 
HETATM 2514 O O   . HOH D 2 .   ? -44.43120 39.59442 -22.10954 1.000 25.78822 ? 230 HOH A O   1 
HETATM 2515 O O   . HOH D 2 .   ? -29.04776 20.80665 -13.89278 1.000 33.55833 ? 231 HOH A O   1 
HETATM 2516 O O   . HOH D 2 .   ? -41.65567 13.32565 -14.81726 1.000 28.07008 ? 232 HOH A O   1 
HETATM 2517 O O   . HOH D 2 .   ? -34.41783 27.89976 -11.48535 1.000 22.95999 ? 233 HOH A O   1 
HETATM 2518 O O   . HOH D 2 .   ? -26.74412 28.45806 -16.06968 1.000 28.34213 ? 234 HOH A O   1 
HETATM 2519 O O   . HOH D 2 .   ? -24.82007 27.59366 -11.69260 1.000 35.74357 ? 235 HOH A O   1 
HETATM 2520 O O   . HOH D 2 .   ? -25.41959 24.30315 -23.56244 1.000 34.93021 ? 236 HOH A O   1 
HETATM 2521 O O   . HOH D 2 .   ? -42.89489 9.07382  -6.73870  1.000 43.38956 ? 237 HOH A O   1 
HETATM 2522 O O   . HOH D 2 .   ? -20.05136 33.09496 -33.35527 1.000 50.46038 ? 238 HOH A O   1 
HETATM 2523 O O   . HOH D 2 .   ? -33.23061 18.66368 -14.48225 1.000 30.42357 ? 239 HOH A O   1 
HETATM 2524 O O   . HOH D 2 .   ? -50.17787 19.05152 -6.90797  1.000 22.92499 ? 240 HOH A O   1 
HETATM 2525 O O   . HOH D 2 .   ? -30.42591 29.26314 -26.67988 1.000 27.99376 ? 241 HOH A O   1 
HETATM 2526 O O   . HOH D 2 .   ? -45.12505 24.36206 -1.76206  1.000 31.21966 ? 242 HOH A O   1 
HETATM 2527 O O   . HOH D 2 .   ? -25.77143 34.52924 -11.83466 1.000 24.96910 ? 243 HOH A O   1 
HETATM 2528 O O   . HOH D 2 .   ? -43.95682 21.09121 -1.61828  1.000 25.70565 ? 244 HOH A O   1 
HETATM 2529 O O   . HOH D 2 .   ? -41.85156 21.57705 -6.39119  1.000 23.57237 ? 245 HOH A O   1 
HETATM 2530 O O   . HOH D 2 .   ? -35.93300 28.61485 -1.25193  1.000 32.91464 ? 246 HOH A O   1 
HETATM 2531 O O   . HOH D 2 .   ? -40.42298 22.25126 -23.87717 1.000 27.02111 ? 247 HOH A O   1 
HETATM 2532 O O   . HOH D 2 .   ? -36.65449 41.56383 -26.42009 1.000 34.46103 ? 248 HOH A O   1 
HETATM 2533 O O   . HOH D 2 .   ? -31.70857 43.30474 -16.18292 1.000 29.38408 ? 249 HOH A O   1 
HETATM 2534 O O   . HOH D 2 .   ? -44.95487 33.03454 -20.36042 1.000 20.77094 ? 250 HOH A O   1 
HETATM 2535 O O   . HOH D 2 .   ? -35.04846 42.00463 -9.75667  1.000 25.53901 ? 251 HOH A O   1 
HETATM 2536 O O   . HOH D 2 .   ? -42.37064 12.69624 -19.69648 1.000 41.69714 ? 252 HOH A O   1 
HETATM 2537 O O   . HOH D 2 .   ? -53.58796 7.45846  -11.32699 1.000 35.17154 ? 253 HOH A O   1 
HETATM 2538 O O   . HOH D 2 .   ? -43.73204 23.19945 -4.83323  1.000 21.21141 ? 254 HOH A O   1 
HETATM 2539 O O   . HOH D 2 .   ? -44.33187 43.13938 -21.39936 1.000 30.11021 ? 255 HOH A O   1 
HETATM 2540 O O   . HOH D 2 .   ? -44.85528 30.64707 -8.76416  1.000 27.25582 ? 256 HOH A O   1 
HETATM 2541 O O   . HOH D 2 .   ? -42.65383 40.78175 -12.63363 1.000 23.49717 ? 257 HOH A O   1 
HETATM 2542 O O   . HOH D 2 .   ? -45.07733 32.87367 -7.08792  1.000 38.28802 ? 258 HOH A O   1 
HETATM 2543 O O   . HOH D 2 .   ? -47.05841 37.70126 -20.25497 1.000 33.49995 ? 259 HOH A O   1 
HETATM 2544 O O   . HOH D 2 .   ? -25.37859 40.82213 -31.11154 1.000 36.86261 ? 260 HOH A O   1 
HETATM 2545 O O   . HOH D 2 .   ? -34.05877 18.59749 -23.63837 1.000 36.54545 ? 261 HOH A O   1 
HETATM 2546 O O   . HOH D 2 .   ? -30.83977 28.74781 -8.97021  1.000 33.79448 ? 262 HOH A O   1 
HETATM 2547 O O   . HOH D 2 .   ? -43.42184 31.82704 -22.42858 1.000 22.05022 ? 263 HOH A O   1 
HETATM 2548 O O   . HOH D 2 .   ? -34.10896 26.43236 -9.06307  1.000 26.71685 ? 264 HOH A O   1 
HETATM 2549 O O   . HOH D 2 .   ? -49.05662 27.61342 -21.17366 1.000 32.97888 ? 265 HOH A O   1 
HETATM 2550 O O   . HOH D 2 .   ? -25.49140 44.05744 -29.67708 1.000 38.94992 ? 266 HOH A O   1 
HETATM 2551 O O   . HOH D 2 .   ? -26.59365 21.31918 -11.28444 1.000 34.78440 ? 267 HOH A O   1 
HETATM 2552 O O   . HOH D 2 .   ? -34.61570 21.75281 -26.28325 1.000 34.83624 ? 268 HOH A O   1 
HETATM 2553 O O   . HOH D 2 .   ? -23.23948 43.45542 -24.28297 1.000 31.70226 ? 269 HOH A O   1 
HETATM 2554 O O   . HOH D 2 .   ? -42.79217 9.87462  -17.12606 1.000 45.49644 ? 270 HOH A O   1 
HETATM 2555 O O   . HOH D 2 .   ? -42.58512 19.02762 -6.90685  1.000 23.66704 ? 271 HOH A O   1 
HETATM 2556 O O   . HOH D 2 .   ? -52.26374 28.46442 -16.08619 1.000 31.25986 ? 272 HOH A O   1 
HETATM 2557 O O   . HOH D 2 .   ? -41.16024 26.12025 -25.97516 1.000 25.42872 ? 273 HOH A O   1 
HETATM 2558 O O   . HOH D 2 .   ? -45.21309 21.05910 -4.15327  1.000 23.97389 ? 274 HOH A O   1 
HETATM 2559 O O   . HOH D 2 .   ? -46.71827 20.93572 -16.61166 1.000 22.30410 ? 275 HOH A O   1 
HETATM 2560 O O   . HOH D 2 .   ? -52.60127 33.79644 -13.39865 1.000 28.75633 ? 276 HOH A O   1 
HETATM 2561 O O   . HOH D 2 .   ? -35.02065 44.13496 -18.33882 1.000 29.84972 ? 277 HOH A O   1 
HETATM 2562 O O   . HOH D 2 .   ? -48.51168 24.86560 -7.12281  1.000 35.58408 ? 278 HOH A O   1 
HETATM 2563 O O   . HOH D 2 .   ? -25.79819 41.98639 -24.10702 1.000 27.58292 ? 279 HOH A O   1 
HETATM 2564 O O   . HOH D 2 .   ? -23.78960 28.74234 -28.34939 1.000 32.29731 ? 280 HOH A O   1 
HETATM 2565 O O   . HOH D 2 .   ? -34.56679 31.46054 -4.25426  1.000 39.59630 ? 281 HOH A O   1 
HETATM 2566 O O   . HOH D 2 .   ? -48.79056 30.64291 -17.38272 1.000 25.44648 ? 282 HOH A O   1 
HETATM 2567 O O   . HOH D 2 .   ? -46.10302 24.82722 -21.28578 1.000 25.96489 ? 283 HOH A O   1 
HETATM 2568 O O   . HOH D 2 .   ? -21.98528 28.95388 -14.49865 1.000 42.24694 ? 284 HOH A O   1 
HETATM 2569 O O   . HOH D 2 .   ? -36.07407 18.20135 -4.31026  1.000 30.50223 ? 285 HOH A O   1 
HETATM 2570 O O   . HOH D 2 .   ? -46.23946 28.79009 -3.55389  1.000 43.89887 ? 286 HOH A O   1 
HETATM 2571 O O   . HOH D 2 .   ? -32.61451 21.46757 -5.52951  1.000 31.06050 ? 287 HOH A O   1 
HETATM 2572 O O   . HOH D 2 .   ? -45.74874 24.66766 -18.70231 1.000 25.92206 ? 288 HOH A O   1 
HETATM 2573 O O   . HOH D 2 .   ? -32.11029 26.33869 -4.88812  1.000 39.08448 ? 289 HOH A O   1 
HETATM 2574 O O   . HOH D 2 .   ? -41.91901 20.36966 -22.28608 1.000 25.02125 ? 290 HOH A O   1 
HETATM 2575 O O   . HOH D 2 .   ? -35.05597 15.02374 -8.02320  1.000 30.64209 ? 291 HOH A O   1 
HETATM 2576 O O   . HOH D 2 .   ? -43.79118 38.40965 -13.40525 1.000 16.43847 ? 292 HOH A O   1 
HETATM 2577 O O   . HOH D 2 .   ? -29.21403 40.03286 -8.49804  1.000 46.28225 ? 293 HOH A O   1 
HETATM 2578 O O   . HOH D 2 .   ? -21.65080 28.50785 -18.34421 1.000 38.97250 ? 294 HOH A O   1 
HETATM 2579 O O   . HOH D 2 .   ? -29.54266 41.39803 -14.16847 1.000 35.82637 ? 295 HOH A O   1 
HETATM 2580 O O   . HOH D 2 .   ? -31.87993 24.87044 -8.67277  1.000 26.55221 ? 296 HOH A O   1 
HETATM 2581 O O   . HOH D 2 .   ? -49.78597 22.60196 -19.73972 1.000 33.18771 ? 297 HOH A O   1 
HETATM 2582 O O   . HOH D 2 .   ? -46.16916 38.10666 -12.49041 1.000 25.39674 ? 298 HOH A O   1 
HETATM 2583 O O   . HOH D 2 .   ? -41.79946 41.81405 -21.77453 1.000 35.00924 ? 299 HOH A O   1 
HETATM 2584 O O   . HOH D 2 .   ? -39.33439 43.16032 -23.57321 1.000 32.67904 ? 300 HOH A O   1 
HETATM 2585 O O   . HOH D 2 .   ? -41.08658 28.67485 -2.05478  1.000 32.38828 ? 301 HOH A O   1 
HETATM 2586 O O   . HOH D 2 .   ? -38.40825 32.27107 -5.36811  1.000 30.15636 ? 302 HOH A O   1 
HETATM 2587 O O   . HOH D 2 .   ? -38.63657 48.54506 -15.44590 1.000 45.74656 ? 303 HOH A O   1 
HETATM 2588 O O   . HOH D 2 .   ? -51.52757 31.40932 -17.52187 1.000 36.48926 ? 304 HOH A O   1 
HETATM 2589 O O   . HOH D 2 .   ? -43.89344 30.52645 -4.76065  1.000 35.21213 ? 305 HOH A O   1 
HETATM 2590 O O   . HOH D 2 .   ? -44.93366 10.02961 -17.92405 1.000 42.31528 ? 306 HOH A O   1 
HETATM 2591 O O   . HOH D 2 .   ? -19.63241 30.78946 -12.74106 1.000 35.16067 ? 307 HOH A O   1 
HETATM 2592 O O   . HOH D 2 .   ? -26.76266 20.28931 -20.73926 1.000 43.44925 ? 308 HOH A O   1 
HETATM 2593 O O   . HOH D 2 .   ? -52.98942 23.64772 -10.95617 1.000 32.97581 ? 309 HOH A O   1 
HETATM 2594 O O   . HOH D 2 .   ? -51.13728 28.12348 -11.89090 1.000 32.17569 ? 310 HOH A O   1 
HETATM 2595 O O   . HOH D 2 .   ? -38.85261 27.05248 -27.08039 1.000 26.28035 ? 311 HOH A O   1 
HETATM 2596 O O   . HOH D 2 .   ? -43.66736 46.19007 -17.57121 1.000 29.53124 ? 312 HOH A O   1 
HETATM 2597 O O   . HOH D 2 .   ? -33.59184 31.33557 -29.08936 1.000 41.15627 ? 313 HOH A O   1 
HETATM 2598 O O   . HOH D 2 .   ? -26.03795 27.76460 -9.24292  1.000 37.57467 ? 314 HOH A O   1 
HETATM 2599 O O   . HOH D 2 .   ? -31.81142 23.98983 -5.91673  1.000 37.12646 ? 315 HOH A O   1 
HETATM 2600 O O   . HOH D 2 .   ? -19.20997 30.19754 -14.67280 1.000 39.39932 ? 316 HOH A O   1 
HETATM 2601 O O   . HOH D 2 .   ? -24.35210 29.66210 -30.72396 1.000 45.83361 ? 317 HOH A O   1 
HETATM 2602 O O   . HOH D 2 .   ? -34.30877 13.69764 -5.67976  1.000 44.94103 ? 318 HOH A O   1 
HETATM 2603 O O   . HOH D 2 .   ? -43.57021 28.31064 -1.87208  1.000 40.42355 ? 319 HOH A O   1 
HETATM 2604 O O   . HOH D 2 .   ? -33.01810 35.32286 -28.36721 1.000 42.93073 ? 320 HOH A O   1 
HETATM 2605 O O   . HOH D 2 .   ? -21.183   38.008   -13.921   1.000 34.79086 ? 321 HOH A O   1 
HETATM 2606 O O   . HOH D 2 .   ? -45.73903 6.54560  -6.02904  1.000 39.67143 ? 322 HOH A O   1 
HETATM 2607 O O   . HOH D 2 .   ? -37.86658 33.59010 -29.11092 1.000 39.40858 ? 323 HOH A O   1 
HETATM 2608 O O   . HOH D 2 .   ? -40.49008 18.34311 -21.43464 1.000 29.26080 ? 324 HOH A O   1 
HETATM 2609 O O   . HOH D 2 .   ? -31.67646 41.18025 -6.40467  1.000 43.92059 ? 325 HOH A O   1 
HETATM 2610 O O   . HOH D 2 .   ? -32.81322 28.11141 -7.11934  1.000 32.46266 ? 326 HOH A O   1 
HETATM 2611 O O   . HOH D 2 .   ? -42.76506 16.39218 -21.05110 1.000 37.43119 ? 327 HOH A O   1 
HETATM 2612 O O   . HOH D 2 .   ? -51.58920 26.01208 -10.57357 1.000 30.43855 ? 328 HOH A O   1 
HETATM 2613 O O   . HOH D 2 .   ? -35.01712 14.98108 -21.39100 1.000 45.18501 ? 329 HOH A O   1 
HETATM 2614 O O   . HOH D 2 .   ? -54.06477 22.80628 -8.42927  1.000 33.79163 ? 330 HOH A O   1 
HETATM 2615 O O   . HOH D 2 .   ? -39.74240 19.02142 -25.62690 1.000 45.07721 ? 331 HOH A O   1 
HETATM 2616 O O   . HOH D 2 .   ? -26.01090 32.32543 -7.79469  1.000 44.24487 ? 332 HOH A O   1 
HETATM 2617 O O   . HOH D 2 .   ? -22.951   45.550   -22.330   1.000 41.67846 ? 333 HOH A O   1 
HETATM 2618 O O   . HOH D 2 .   ? -30.08147 18.45300 -17.94119 1.000 45.02173 ? 334 HOH A O   1 
HETATM 2619 O O   . HOH D 2 .   ? -45.39230 27.98613 -24.81832 1.000 39.75021 ? 335 HOH A O   1 
HETATM 2620 O O   . HOH D 2 .   ? -25.84691 27.05909 -28.18523 1.000 37.51271 ? 336 HOH A O   1 
HETATM 2621 O O   . HOH D 2 .   ? -44.46030 17.47061 -22.30922 1.000 33.19612 ? 337 HOH A O   1 
HETATM 2622 O O   . HOH D 2 .   ? -35.01930 36.11080 -29.15491 1.000 46.50020 ? 338 HOH A O   1 
HETATM 2623 O O   . HOH D 2 .   ? -40.92108 42.11710 -26.45585 1.000 38.32016 ? 339 HOH A O   1 
HETATM 2624 O O   . HOH D 2 .   ? -41.76261 33.24698 -26.73025 1.000 30.82908 ? 340 HOH A O   1 
HETATM 2625 O O   . HOH D 2 .   ? -43.65400 19.13897 -23.85899 1.000 36.68601 ? 341 HOH A O   1 
HETATM 2626 O O   . HOH D 2 .   ? -40.70099 23.44591 -26.27045 1.000 28.64413 ? 342 HOH A O   1 
HETATM 2627 O O   . HOH D 2 .   ? -34.02878 42.65958 -6.95699  1.000 39.47453 ? 343 HOH A O   1 
HETATM 2628 O O   . HOH D 2 .   ? -39.19257 17.26453 -23.54280 1.000 37.80780 ? 344 HOH A O   1 
HETATM 2629 O O   . HOH D 2 .   ? -43.65931 41.23055 -24.19551 1.000 36.59340 ? 345 HOH A O   1 
HETATM 2630 O O   . HOH D 2 .   ? -27.58816 21.66359 -16.18179 1.000 36.93524 ? 346 HOH A O   1 
HETATM 2631 O O   . HOH D 2 .   ? -31.47943 31.70316 -26.88670 1.000 27.77519 ? 347 HOH A O   1 
HETATM 2632 O O   . HOH D 2 .   ? -11.278   34.213   -25.808   1.000 45.07804 ? 348 HOH A O   1 
HETATM 2633 O O   . HOH D 2 .   ? -32.30170 19.86701 -3.55528  1.000 45.46073 ? 349 HOH A O   1 
HETATM 2634 O O   . HOH D 2 .   ? -43.46696 26.47248 -27.34342 1.000 38.07190 ? 350 HOH A O   1 
HETATM 2635 O O   . HOH D 2 .   ? -42.87853 9.61919  -11.55957 1.000 38.10336 ? 351 HOH A O   1 
HETATM 2636 O O   . HOH D 2 .   ? -45.20293 8.50495  -12.94648 1.000 42.87974 ? 352 HOH A O   1 
HETATM 2637 O O   . HOH D 2 .   ? -41.21147 11.30766 -12.88660 1.000 36.54685 ? 353 HOH A O   1 
HETATM 2638 O O   . HOH D 2 .   ? -24.00242 28.38700 -16.65341 1.000 34.00579 ? 354 HOH A O   1 
HETATM 2639 O O   . HOH D 2 .   ? -32.92837 20.33412 -27.14982 1.000 45.73432 ? 355 HOH A O   1 
HETATM 2640 O O   . HOH D 2 .   ? -21.454   33.250   -7.484    1.000 49.88423 ? 356 HOH A O   1 
HETATM 2641 O O   . HOH D 2 .   ? -45.26099 30.69944 -24.26467 1.000 32.66160 ? 357 HOH A O   1 
HETATM 2642 O O   . HOH D 2 .   ? -24.61142 34.81289 -9.06913  1.000 36.73347 ? 358 HOH A O   1 
HETATM 2643 O O   . HOH D 2 .   ? -39.11269 36.40347 -28.79265 1.000 37.93458 ? 359 HOH A O   1 
HETATM 2644 O O   . HOH D 2 .   ? -39.19812 29.38516 -28.41853 1.000 28.17867 ? 360 HOH A O   1 
HETATM 2645 O O   . HOH D 2 .   ? -31.95780 44.92711 -14.30772 1.000 41.77968 ? 361 HOH A O   1 
HETATM 2646 O O   . HOH D 2 .   ? -42.13695 8.68802  -9.20494  1.000 41.06858 ? 362 HOH A O   1 
HETATM 2647 O O   . HOH D 2 .   ? -44.76504 6.53387  -9.44355  1.000 42.97748 ? 363 HOH A O   1 
HETATM 2648 O O   . HOH D 2 .   ? -25.70017 24.92732 -26.96460 1.000 39.79107 ? 364 HOH A O   1 
HETATM 2649 O O   . HOH D 2 .   ? -42.54183 44.01986 -24.03583 1.000 35.30414 ? 365 HOH A O   1 
HETATM 2650 O O   . HOH D 2 .   ? -34.16549 18.68835 -2.21311  1.000 41.42900 ? 366 HOH A O   1 
HETATM 2651 O O   . HOH D 2 .   ? -45.67998 5.71651  -3.95504  1.000 41.37987 ? 367 HOH A O   1 
HETATM 2652 O O   . HOH D 2 .   ? -25.11923 37.55569 -8.37117  1.000 41.32646 ? 368 HOH A O   1 
HETATM 2653 O O   . HOH D 2 .   ? -54.35700 31.38303 -13.48026 0.33  28.40793 ? 369 HOH A O   1 
HETATM 2654 O O   . HOH D 2 .   ? -18.81081 27.81743 -14.33422 1.000 49.52762 ? 370 HOH A O   1 
HETATM 2655 O O   . HOH D 2 .   ? -41.31647 35.04116 -28.48679 1.000 42.41382 ? 371 HOH A O   1 
HETATM 2656 O O   . HOH E 2 .   ? -46.46083 54.80258 1.01341   1.000 43.18454 ? 201 HOH B O   1 
HETATM 2657 O O   . HOH E 2 .   ? -33.39213 44.03306 7.59591   1.000 36.10775 ? 202 HOH B O   1 
HETATM 2658 O O   . HOH E 2 .   ? -47.96909 27.76436 6.56334   1.000 24.52935 ? 203 HOH B O   1 
HETATM 2659 O O   . HOH E 2 .   ? -34.37601 44.45226 16.83282  1.000 43.13639 ? 204 HOH B O   1 
HETATM 2660 O O   . HOH E 2 .   ? -24.71243 34.83843 4.64874   1.000 47.39073 ? 205 HOH B O   1 
HETATM 2661 O O   . HOH E 2 .   ? -32.52928 29.17255 18.12666  1.000 32.57224 ? 206 HOH B O   1 
HETATM 2662 O O   . HOH E 2 .   ? -32.08453 35.29238 -6.37322  1.000 34.55435 ? 207 HOH B O   1 
HETATM 2663 O O   . HOH E 2 .   ? -37.41927 40.18313 19.98022  1.000 33.89202 ? 208 HOH B O   1 
HETATM 2664 O O   . HOH E 2 .   ? -39.95335 44.10960 11.73359  1.000 30.15722 ? 209 HOH B O   1 
HETATM 2665 O O   . HOH E 2 .   ? -33.42075 45.19663 14.20430  1.000 36.60590 ? 210 HOH B O   1 
HETATM 2666 O O   . HOH E 2 .   ? -33.20439 34.86060 8.33118   1.000 27.30988 ? 211 HOH B O   1 
HETATM 2667 O O   . HOH E 2 .   ? -47.19707 53.52502 4.81039   1.000 32.13713 ? 212 HOH B O   1 
HETATM 2668 O O   . HOH E 2 .   ? -44.88386 29.53531 13.54183  1.000 26.24741 ? 213 HOH B O   1 
HETATM 2669 O O   . HOH E 2 .   ? -49.36518 54.49436 -3.98735  1.000 38.54650 ? 214 HOH B O   1 
HETATM 2670 O O   . HOH E 2 .   ? -31.72446 19.30387 9.50060   1.000 37.11248 ? 215 HOH B O   1 
HETATM 2671 O O   . HOH E 2 .   ? -46.51251 18.65832 11.20008  1.000 31.28122 ? 216 HOH B O   1 
HETATM 2672 O O   . HOH E 2 .   ? -48.17096 39.86868 10.54420  1.000 30.06614 ? 217 HOH B O   1 
HETATM 2673 O O   . HOH E 2 .   ? -37.60373 48.43436 1.43779   1.000 32.48940 ? 218 HOH B O   1 
HETATM 2674 O O   . HOH E 2 .   ? -49.13176 34.59947 14.23962  1.000 44.44338 ? 219 HOH B O   1 
HETATM 2675 O O   . HOH E 2 .   ? -46.55372 41.84977 9.95810   1.000 28.76213 ? 220 HOH B O   1 
HETATM 2676 O O   . HOH E 2 .   ? -35.11408 47.35822 1.17867   1.000 31.04138 ? 221 HOH B O   1 
HETATM 2677 O O   . HOH E 2 .   ? -30.94549 33.71795 2.18096   1.000 37.55669 ? 222 HOH B O   1 
HETATM 2678 O O   . HOH E 2 .   ? -41.62763 49.33414 8.03047   1.000 32.88147 ? 223 HOH B O   1 
HETATM 2679 O O   . HOH E 2 .   ? -44.37388 19.69646 14.60553  1.000 40.51453 ? 224 HOH B O   1 
HETATM 2680 O O   . HOH E 2 .   ? -38.79264 50.21580 4.90804   1.000 40.42486 ? 225 HOH B O   1 
HETATM 2681 O O   . HOH E 2 .   ? -26.86358 34.21544 9.15614   1.000 37.95322 ? 226 HOH B O   1 
HETATM 2682 O O   . HOH E 2 .   ? -34.75049 30.86275 -1.94054  1.000 35.40699 ? 227 HOH B O   1 
HETATM 2683 O O   . HOH E 2 .   ? -50.69379 58.65845 4.12526   1.000 52.24701 ? 228 HOH B O   1 
HETATM 2684 O O   . HOH E 2 .   ? -22.23184 35.05096 13.68112  1.000 37.28881 ? 229 HOH B O   1 
HETATM 2685 O O   . HOH E 2 .   ? -19.069   32.017   26.060    1.000 36.37619 ? 230 HOH B O   1 
HETATM 2686 O O   . HOH E 2 .   ? -42.10410 29.33146 17.30073  1.000 36.06596 ? 231 HOH B O   1 
HETATM 2687 O O   . HOH E 2 .   ? -44.97545 32.11196 1.94731   1.000 27.63342 ? 232 HOH B O   1 
HETATM 2688 O O   . HOH E 2 .   ? -44.45799 23.11094 15.29509  1.000 35.36881 ? 233 HOH B O   1 
HETATM 2689 O O   . HOH E 2 .   ? -25.74317 28.18399 4.97120   1.000 34.48700 ? 234 HOH B O   1 
HETATM 2690 O O   . HOH E 2 .   ? -28.64460 41.70471 11.31177  1.000 37.31541 ? 235 HOH B O   1 
HETATM 2691 O O   . HOH E 2 .   ? -45.10696 38.21113 -5.08935  1.000 32.95693 ? 236 HOH B O   1 
HETATM 2692 O O   . HOH E 2 .   ? -34.46881 34.74722 4.60100   1.000 26.20859 ? 237 HOH B O   1 
HETATM 2693 O O   . HOH E 2 .   ? -34.97303 18.60246 11.63274  1.000 34.70666 ? 238 HOH B O   1 
HETATM 2694 O O   . HOH E 2 .   ? -22.28746 28.25343 24.46750  1.000 43.84790 ? 239 HOH B O   1 
HETATM 2695 O O   . HOH E 2 .   ? -25.43148 38.49642 16.32123  1.000 35.28663 ? 240 HOH B O   1 
HETATM 2696 O O   . HOH E 2 .   ? -39.22285 30.85205 20.56026  1.000 35.10527 ? 241 HOH B O   1 
HETATM 2697 O O   . HOH E 2 .   ? -41.82233 41.11470 -0.44224  1.000 22.16945 ? 242 HOH B O   1 
HETATM 2698 O O   . HOH E 2 .   ? -29.06069 41.88891 6.71846   1.000 38.14422 ? 243 HOH B O   1 
HETATM 2699 O O   . HOH E 2 .   ? -18.14832 30.11769 19.01857  1.000 38.83310 ? 244 HOH B O   1 
HETATM 2700 O O   . HOH E 2 .   ? -43.83809 41.71579 -5.08155  1.000 26.83842 ? 245 HOH B O   1 
HETATM 2701 O O   . HOH E 2 .   ? -42.58950 21.83475 5.90653   1.000 27.17041 ? 246 HOH B O   1 
HETATM 2702 O O   . HOH E 2 .   ? -50.14965 43.61491 0.04392   1.000 25.90611 ? 247 HOH B O   1 
HETATM 2703 O O   . HOH E 2 .   ? -34.13008 36.22031 2.14219   1.000 26.71351 ? 248 HOH B O   1 
HETATM 2704 O O   . HOH E 2 .   ? -31.62374 30.12917 0.48842   1.000 34.42772 ? 249 HOH B O   1 
HETATM 2705 O O   . HOH E 2 .   ? -34.38215 41.29307 19.32341  1.000 39.86009 ? 250 HOH B O   1 
HETATM 2706 O O   . HOH E 2 .   ? -25.79825 20.68272 17.35293  1.000 44.68476 ? 251 HOH B O   1 
HETATM 2707 O O   . HOH E 2 .   ? -42.66776 53.57120 -0.16885  1.000 41.79964 ? 252 HOH B O   1 
HETATM 2708 O O   . HOH E 2 .   ? -30.59564 33.59013 19.97556  1.000 45.33734 ? 253 HOH B O   1 
HETATM 2709 O O   . HOH E 2 .   ? -34.97000 20.61702 2.80601   1.000 31.80173 ? 254 HOH B O   1 
HETATM 2710 O O   . HOH E 2 .   ? -46.92548 25.03918 13.66804  1.000 36.66148 ? 255 HOH B O   1 
HETATM 2711 O O   . HOH E 2 .   ? -38.03500 46.74272 -0.55089  1.000 31.61524 ? 256 HOH B O   1 
HETATM 2712 O O   . HOH E 2 .   ? -45.23672 41.68085 -2.63537  1.000 28.15210 ? 257 HOH B O   1 
HETATM 2713 O O   . HOH E 2 .   ? -48.75286 32.14571 10.53300  1.000 34.52605 ? 258 HOH B O   1 
HETATM 2714 O O   . HOH E 2 .   ? -22.84440 33.77595 23.41765  1.000 30.84374 ? 259 HOH B O   1 
HETATM 2715 O O   . HOH E 2 .   ? -26.67490 41.32858 4.52024   1.000 41.82816 ? 260 HOH B O   1 
HETATM 2716 O O   . HOH E 2 .   ? -53.43708 55.12878 4.56268   1.000 36.59510 ? 261 HOH B O   1 
HETATM 2717 O O   . HOH E 2 .   ? -43.77972 39.60948 -1.99266  1.000 28.05397 ? 262 HOH B O   1 
HETATM 2718 O O   . HOH E 2 .   ? -52.15162 34.61739 9.05952   1.000 31.70208 ? 263 HOH B O   1 
HETATM 2719 O O   . HOH E 2 .   ? -36.15388 44.37801 -2.68068  1.000 31.62869 ? 264 HOH B O   1 
HETATM 2720 O O   . HOH E 2 .   ? -43.60654 30.95126 15.65399  1.000 30.61786 ? 265 HOH B O   1 
HETATM 2721 O O   . HOH E 2 .   ? -22.14595 33.51025 7.46178   1.000 43.72607 ? 266 HOH B O   1 
HETATM 2722 O O   . HOH E 2 .   ? -26.47928 17.80163 16.26805  1.000 50.60752 ? 267 HOH B O   1 
HETATM 2723 O O   . HOH E 2 .   ? -32.99015 19.46174 19.29147  1.000 44.69965 ? 268 HOH B O   1 
HETATM 2724 O O   . HOH E 2 .   ? -37.38132 49.36064 7.29724   1.000 42.61568 ? 269 HOH B O   1 
HETATM 2725 O O   . HOH E 2 .   ? -45.28048 29.69235 0.37620   1.000 39.78933 ? 270 HOH B O   1 
HETATM 2726 O O   . HOH E 2 .   ? -23.40727 34.37496 20.93617  1.000 31.95655 ? 271 HOH B O   1 
HETATM 2727 O O   . HOH E 2 .   ? -40.17786 40.50000 16.90929  1.000 35.55427 ? 272 HOH B O   1 
HETATM 2728 O O   . HOH E 2 .   ? -53.11758 28.32635 12.62431  1.000 44.42041 ? 273 HOH B O   1 
HETATM 2729 O O   . HOH E 2 .   ? -32.18693 36.03668 -2.01799  1.000 39.58247 ? 274 HOH B O   1 
HETATM 2730 O O   . HOH E 2 .   ? -42.47766 43.59410 0.08166   1.000 26.79524 ? 275 HOH B O   1 
HETATM 2731 O O   . HOH E 2 .   ? -44.47679 52.63270 11.00577  1.000 44.89207 ? 276 HOH B O   1 
HETATM 2732 O O   . HOH E 2 .   ? -52.51397 28.77129 6.62800   1.000 31.00443 ? 277 HOH B O   1 
HETATM 2733 O O   . HOH E 2 .   ? -43.62601 32.49597 -2.29937  1.000 40.77158 ? 278 HOH B O   1 
HETATM 2734 O O   . HOH E 2 .   ? -39.05266 15.33939 11.76503  1.000 43.32486 ? 279 HOH B O   1 
HETATM 2735 O O   . HOH E 2 .   ? -45.92037 38.09439 14.43680  1.000 36.08925 ? 280 HOH B O   1 
HETATM 2736 O O   . HOH E 2 .   ? -27.62124 43.59691 2.95129   1.000 48.19975 ? 281 HOH B O   1 
HETATM 2737 O O   . HOH E 2 .   ? -35.94601 33.78544 -5.54321  1.000 32.04585 ? 282 HOH B O   1 
HETATM 2738 O O   . HOH E 2 .   ? -41.21836 36.83311 19.11224  1.000 36.28641 ? 283 HOH B O   1 
HETATM 2739 O O   . HOH E 2 .   ? -38.69073 14.30749 9.03754   1.000 40.51837 ? 284 HOH B O   1 
HETATM 2740 O O   . HOH E 2 .   ? -48.29413 37.61309 0.20030   1.000 39.48606 ? 285 HOH B O   1 
HETATM 2741 O O   . HOH E 2 .   ? -31.05326 40.74623 17.86067  1.000 45.77736 ? 286 HOH B O   1 
HETATM 2742 O O   . HOH E 2 .   ? -32.00074 37.59804 1.70811   1.000 31.57670 ? 287 HOH B O   1 
HETATM 2743 O O   . HOH E 2 .   ? -41.74996 20.73603 14.90795  1.000 41.65724 ? 288 HOH B O   1 
HETATM 2744 O O   . HOH E 2 .   ? -49.61548 40.09796 12.97114  1.000 37.27804 ? 289 HOH B O   1 
HETATM 2745 O O   . HOH E 2 .   ? -17.37306 30.43802 21.76905  1.000 36.53111 ? 290 HOH B O   1 
HETATM 2746 O O   . HOH E 2 .   ? -29.45855 21.26922 6.96571   1.000 36.07413 ? 291 HOH B O   1 
HETATM 2747 O O   . HOH E 2 .   ? -29.20492 22.47444 1.64437   1.000 43.77055 ? 292 HOH B O   1 
HETATM 2748 O O   . HOH E 2 .   ? -45.63736 38.09263 11.96860  1.000 29.73311 ? 293 HOH B O   1 
HETATM 2749 O O   . HOH E 2 .   ? -40.98491 33.93236 -4.79128  1.000 34.48739 ? 294 HOH B O   1 
HETATM 2750 O O   . HOH E 2 .   ? -20.94163 33.38680 10.77995  1.000 41.45582 ? 295 HOH B O   1 
HETATM 2751 O O   . HOH E 2 .   ? -46.22827 24.67387 5.64780   1.000 25.97553 ? 296 HOH B O   1 
HETATM 2752 O O   . HOH E 2 .   ? -46.60695 38.21884 -2.97866  1.000 38.42796 ? 297 HOH B O   1 
HETATM 2753 O O   . HOH E 2 .   ? -25.84509 41.42806 13.76989  1.000 46.17036 ? 298 HOH B O   1 
HETATM 2754 O O   . HOH E 2 .   ? -43.73665 24.34559 6.52628   1.000 23.32071 ? 299 HOH B O   1 
HETATM 2755 O O   . HOH E 2 .   ? -41.72687 42.35323 15.40886  1.000 28.83039 ? 300 HOH B O   1 
HETATM 2756 O O   . HOH E 2 .   ? -38.62361 48.13210 13.99717  1.000 50.89193 ? 301 HOH B O   1 
HETATM 2757 O O   . HOH E 2 .   ? -21.12248 20.52065 9.21764   1.000 58.41776 ? 302 HOH B O   1 
HETATM 2758 O O   . HOH E 2 .   ? -16.80495 24.00764 22.72011  1.000 43.46059 ? 303 HOH B O   1 
HETATM 2759 O O   . HOH E 2 .   ? -39.10104 19.55123 16.77794  1.000 41.76085 ? 304 HOH B O   1 
HETATM 2760 O O   . HOH E 2 .   ? -53.00582 39.17007 3.94165   1.000 32.01096 ? 305 HOH B O   1 
HETATM 2761 O O   . HOH E 2 .   ? -25.26073 20.17043 6.24121   1.000 51.61342 ? 306 HOH B O   1 
HETATM 2762 O O   . HOH E 2 .   ? -22.02275 27.67271 3.85077   1.000 46.94642 ? 307 HOH B O   1 
HETATM 2763 O O   . HOH E 2 .   ? -32.54956 41.07044 -1.41892  1.000 34.78484 ? 308 HOH B O   1 
HETATM 2764 O O   . HOH E 2 .   ? -43.53843 34.37208 -4.82696  1.000 39.47706 ? 309 HOH B O   1 
HETATM 2765 O O   . HOH E 2 .   ? -40.63122 16.20058 14.67081  1.000 35.03433 ? 310 HOH B O   1 
HETATM 2766 O O   . HOH E 2 .   ? -51.17629 34.57512 5.01930   1.000 32.48553 ? 311 HOH B O   1 
HETATM 2767 O O   . HOH E 2 .   ? -19.77763 32.08172 5.29005   1.000 45.69999 ? 312 HOH B O   1 
HETATM 2768 O O   . HOH E 2 .   ? -38.98999 35.66018 20.05589  1.000 34.99662 ? 313 HOH B O   1 
HETATM 2769 O O   . HOH E 2 .   ? -45.61395 55.94843 -0.69518  1.000 43.55843 ? 314 HOH B O   1 
HETATM 2770 O O   . HOH E 2 .   ? -18.966   30.946   28.854    1.000 46.44521 ? 315 HOH B O   1 
HETATM 2771 O O   . HOH E 2 .   ? -19.15378 32.46991 7.89435   1.000 47.92896 ? 316 HOH B O   1 
HETATM 2772 O O   . HOH E 2 .   ? -43.67172 16.21225 10.86881  1.000 31.56097 ? 317 HOH B O   1 
HETATM 2773 O O   . HOH E 2 .   ? -31.92682 38.47910 -1.21031  1.000 39.35266 ? 318 HOH B O   1 
HETATM 2774 O O   . HOH E 2 .   ? -42.80145 46.22070 14.12717  1.000 39.28415 ? 319 HOH B O   1 
HETATM 2775 O O   . HOH E 2 .   ? -32.86823 34.48188 0.26757   1.000 34.82901 ? 320 HOH B O   1 
HETATM 2776 O O   . HOH E 2 .   ? -31.91593 21.44807 -0.55133  1.000 43.98369 ? 321 HOH B O   1 
HETATM 2777 O O   . HOH E 2 .   ? -37.73588 29.41504 22.36272  1.000 52.78073 ? 322 HOH B O   1 
HETATM 2778 O O   . HOH E 2 .   ? -51.57825 36.81205 3.71123   1.000 31.01917 ? 323 HOH B O   1 
HETATM 2779 O O   . HOH E 2 .   ? -40.43671 44.57096 14.69956  1.000 36.39377 ? 324 HOH B O   1 
HETATM 2780 O O   . HOH E 2 .   ? -42.65713 17.11996 13.71047  1.000 44.82073 ? 325 HOH B O   1 
HETATM 2781 O O   . HOH E 2 .   ? -54.10712 39.98868 1.53339   1.000 38.63009 ? 326 HOH B O   1 
HETATM 2782 O O   . HOH E 2 .   ? -45.30289 34.64233 18.00556  1.000 42.52810 ? 327 HOH B O   1 
HETATM 2783 O O   . HOH E 2 .   ? -38.79172 45.75580 16.47282  1.000 39.74634 ? 328 HOH B O   1 
HETATM 2784 O O   . HOH E 2 .   ? -32.06408 42.80376 -3.36038  1.000 39.79435 ? 329 HOH B O   1 
HETATM 2785 O O   . HOH E 2 .   ? -34.23250 20.06052 0.09018   1.000 40.75474 ? 330 HOH B O   1 
HETATM 2786 O O   . HOH E 2 .   ? -23.74531 34.15143 9.14276   1.000 42.48439 ? 331 HOH B O   1 
HETATM 2787 O O   . HOH E 2 .   ? -40.51018 39.42762 19.37343  1.000 38.07814 ? 332 HOH B O   1 
HETATM 2788 O O   . HOH E 2 .   ? -31.38102 30.98820 19.80127  1.000 39.28642 ? 333 HOH B O   1 
HETATM 2789 O O   . HOH E 2 .   ? -42.88883 52.99597 4.55153   1.000 42.17218 ? 334 HOH B O   1 
HETATM 2790 O O   . HOH E 2 .   ? -36.31886 28.10323 23.59650  1.000 49.04456 ? 335 HOH B O   1 
HETATM 2791 O O   . HOH E 2 .   ? -45.99405 49.81285 13.16266  1.000 46.41398 ? 336 HOH B O   1 
HETATM 2792 O O   . HOH E 2 .   ? -47.12674 39.57238 -1.35970  1.000 38.38462 ? 337 HOH B O   1 
HETATM 2793 O O   . HOH E 2 .   ? -24.60444 28.02765 2.10940   1.000 43.40109 ? 338 HOH B O   1 
HETATM 2794 O O   . HOH E 2 .   ? -27.64607 41.06752 9.16341   1.000 34.98816 ? 339 HOH B O   1 
HETATM 2795 O O   . HOH E 2 .   ? -41.46619 28.86929 20.53259  1.000 47.84603 ? 340 HOH B O   1 
HETATM 2796 O O   . HOH E 2 .   ? -42.15285 18.54242 17.29264  1.000 45.91999 ? 341 HOH B O   1 
HETATM 2797 O O   . HOH E 2 .   ? -45.20115 31.95387 17.41830  1.000 39.68785 ? 342 HOH B O   1 
HETATM 2798 O O   . HOH E 2 .   ? -45.76494 54.26055 6.58504   1.000 48.13456 ? 343 HOH B O   1 
HETATM 2799 O O   . HOH E 2 .   ? -31.06554 17.51577 11.41719  1.000 45.84741 ? 344 HOH B O   1 
HETATM 2800 O O   . HOH E 2 .   ? -40.86745 51.59110 5.98442   1.000 38.36986 ? 345 HOH B O   1 
HETATM 2801 O O   . HOH E 2 .   ? -42.01153 54.20194 2.27242   1.000 39.50449 ? 346 HOH B O   1 
HETATM 2802 O O   . HOH E 2 .   ? -32.00306 17.66468 7.20126   1.000 43.50210 ? 347 HOH B O   1 
HETATM 2803 O O   . HOH E 2 .   ? -39.18945 33.60117 21.48029  1.000 45.58073 ? 348 HOH B O   1 
HETATM 2804 O O   . HOH E 2 .   ? -37.85020 51.44266 0.96707   1.000 43.15684 ? 349 HOH B O   1 
HETATM 2805 O O   . HOH E 2 .   ? -16.77896 30.27576 16.88170  1.000 49.97073 ? 350 HOH B O   1 
HETATM 2806 O O   . HOH E 2 .   ? -30.07215 37.39759 -6.04923  1.000 37.98067 ? 351 HOH B O   1 
HETATM 2807 O O   . HOH E 2 .   ? -34.32491 44.15191 -4.76616  1.000 47.40073 ? 352 HOH B O   1 
HETATM 2808 O O   . HOH E 2 .   ? -45.33996 56.81983 -2.77195  1.000 46.27093 ? 353 HOH B O   1 
HETATM 2809 O O   . HOH E 2 .   ? -25.45367 43.21146 3.94046   1.000 57.95059 ? 354 HOH B O   1 
HETATM 2810 O O   . HOH E 2 .   ? -46.02968 48.30212 15.04148  1.000 33.59899 ? 355 HOH B O   1 
HETATM 2811 O O   . HOH E 2 .   ? -43.91564 56.35395 2.80205   1.000 41.52864 ? 356 HOH B O   1 
HETATM 2812 O O   . HOH F 2 .   ? -48.84108 52.11784 36.56234  1.000 38.69782 ? 201 HOH C O   1 
HETATM 2813 O O   . HOH F 2 .   ? -48.29113 31.32934 29.51674  1.000 38.07420 ? 202 HOH C O   1 
HETATM 2814 O O   . HOH F 2 .   ? -31.50084 36.45972 44.72901  1.000 32.42475 ? 203 HOH C O   1 
HETATM 2815 O O   . HOH F 2 .   ? -33.17701 39.14304 49.73356  1.000 33.02450 ? 204 HOH C O   1 
HETATM 2816 O O   . HOH F 2 .   ? -34.74164 21.66504 30.70845  1.000 41.70799 ? 205 HOH C O   1 
HETATM 2817 O O   . HOH F 2 .   ? -35.35013 27.89335 31.65247  1.000 29.67033 ? 206 HOH C O   1 
HETATM 2818 O O   . HOH F 2 .   ? -30.11281 36.15729 25.83048  1.000 38.86448 ? 207 HOH C O   1 
HETATM 2819 O O   . HOH F 2 .   ? -42.37167 52.35203 24.09616  1.000 42.41640 ? 208 HOH C O   1 
HETATM 2820 O O   . HOH F 2 .   ? -41.68850 53.47105 34.34331  1.000 37.35124 ? 209 HOH C O   1 
HETATM 2821 O O   . HOH F 2 .   ? -41.82690 39.84154 23.08621  1.000 32.28980 ? 210 HOH C O   1 
HETATM 2822 O O   . HOH F 2 .   ? -50.82245 37.69530 36.97818  1.000 22.36583 ? 211 HOH C O   1 
HETATM 2823 O O   . HOH F 2 .   ? -35.12845 32.88837 23.42571  1.000 40.24322 ? 212 HOH C O   1 
HETATM 2824 O O   . HOH F 2 .   ? -54.15717 46.31540 32.25215  1.000 24.54178 ? 213 HOH C O   1 
HETATM 2825 O O   . HOH F 2 .   ? -27.49421 58.62505 25.34820  1.000 48.01305 ? 214 HOH C O   1 
HETATM 2826 O O   . HOH F 2 .   ? -39.47135 50.65804 43.35391  1.000 43.94664 ? 215 HOH C O   1 
HETATM 2827 O O   . HOH F 2 .   ? -33.27085 38.33025 45.29215  1.000 31.23849 ? 216 HOH C O   1 
HETATM 2828 O O   . HOH F 2 .   ? -35.65453 38.49150 39.07958  1.000 27.83540 ? 217 HOH C O   1 
HETATM 2829 O O   . HOH F 2 .   ? -54.81056 34.51698 30.69506  1.000 39.02835 ? 218 HOH C O   1 
HETATM 2830 O O   . HOH F 2 .   ? -51.72118 40.87828 29.70970  1.000 37.89366 ? 219 HOH C O   1 
HETATM 2831 O O   . HOH F 2 .   ? -45.16620 39.52029 26.34725  1.000 29.49383 ? 220 HOH C O   1 
HETATM 2832 O O   . HOH F 2 .   ? -31.39082 23.37871 38.34230  1.000 34.10181 ? 221 HOH C O   1 
HETATM 2833 O O   . HOH F 2 .   ? -24.39697 41.37540 35.20084  1.000 49.80464 ? 222 HOH C O   1 
HETATM 2834 O O   . HOH F 2 .   ? -50.22627 43.63615 28.15655  1.000 33.92357 ? 223 HOH C O   1 
HETATM 2835 O O   . HOH F 2 .   ? -35.22808 44.10074 43.26571  1.000 31.56575 ? 224 HOH C O   1 
HETATM 2836 O O   . HOH F 2 .   ? -49.77799 52.86220 31.87774  1.000 37.29083 ? 225 HOH C O   1 
HETATM 2837 O O   . HOH F 2 .   ? -43.62921 24.26297 28.02138  1.000 37.11500 ? 226 HOH C O   1 
HETATM 2838 O O   . HOH F 2 .   ? -29.18051 43.39723 34.55497  1.000 36.73070 ? 227 HOH C O   1 
HETATM 2839 O O   . HOH F 2 .   ? -31.74250 48.98849 38.95005  1.000 37.02103 ? 228 HOH C O   1 
HETATM 2840 O O   . HOH F 2 .   ? -25.62902 46.14477 36.22362  1.000 40.90229 ? 229 HOH C O   1 
HETATM 2841 O O   . HOH F 2 .   ? -41.58038 26.94982 46.13034  1.000 27.40992 ? 230 HOH C O   1 
HETATM 2842 O O   . HOH F 2 .   ? -43.31326 30.25687 48.29078  1.000 35.48667 ? 231 HOH C O   1 
HETATM 2843 O O   . HOH F 2 .   ? -36.99670 15.90853 38.77342  1.000 35.62491 ? 232 HOH C O   1 
HETATM 2844 O O   . HOH F 2 .   ? -31.39401 25.05192 42.20249  1.000 27.71970 ? 233 HOH C O   1 
HETATM 2845 O O   . HOH F 2 .   ? -34.22316 22.75167 35.61168  1.000 28.73550 ? 234 HOH C O   1 
HETATM 2846 O O   . HOH F 2 .   ? -54.09152 34.45495 36.78114  1.000 29.56589 ? 235 HOH C O   1 
HETATM 2847 O O   . HOH F 2 .   ? -34.48510 39.39620 35.20493  1.000 29.69391 ? 236 HOH C O   1 
HETATM 2848 O O   . HOH F 2 .   ? -47.28298 37.53974 29.77599  1.000 29.15200 ? 237 HOH C O   1 
HETATM 2849 O O   . HOH F 2 .   ? -29.49118 31.74683 35.77813  1.000 38.49377 ? 238 HOH C O   1 
HETATM 2850 O O   . HOH F 2 .   ? -40.44199 27.78246 48.58088  1.000 27.23425 ? 239 HOH C O   1 
HETATM 2851 O O   . HOH F 2 .   ? -32.54174 26.43563 43.96596  1.000 32.04435 ? 240 HOH C O   1 
HETATM 2852 O O   . HOH F 2 .   ? -49.12860 45.44761 37.67688  1.000 24.92053 ? 241 HOH C O   1 
HETATM 2853 O O   . HOH F 2 .   ? -44.71721 27.20252 32.82430  1.000 29.27318 ? 242 HOH C O   1 
HETATM 2854 O O   . HOH F 2 .   ? -37.44796 31.01763 26.56696  1.000 35.84448 ? 243 HOH C O   1 
HETATM 2855 O O   . HOH F 2 .   ? -30.14635 31.27662 26.45555  1.000 41.14389 ? 244 HOH C O   1 
HETATM 2856 O O   . HOH F 2 .   ? -24.70904 51.29249 24.68823  1.000 46.03541 ? 245 HOH C O   1 
HETATM 2857 O O   . HOH F 2 .   ? -36.69074 44.79203 25.67565  1.000 30.12125 ? 246 HOH C O   1 
HETATM 2858 O O   . HOH F 2 .   ? -34.61328 14.59646 44.27332  1.000 44.26301 ? 247 HOH C O   1 
HETATM 2859 O O   . HOH F 2 .   ? -44.51514 23.09509 43.47119  1.000 25.81064 ? 248 HOH C O   1 
HETATM 2860 O O   . HOH F 2 .   ? -38.84170 29.37996 43.97550  1.000 26.25355 ? 249 HOH C O   1 
HETATM 2861 O O   . HOH F 2 .   ? -54.70128 34.96354 34.20858  1.000 32.61689 ? 250 HOH C O   1 
HETATM 2862 O O   . HOH F 2 .   ? -30.51781 24.65387 36.22235  1.000 35.87789 ? 251 HOH C O   1 
HETATM 2863 O O   . HOH F 2 .   ? -42.21491 26.48114 33.70033  1.000 24.90096 ? 252 HOH C O   1 
HETATM 2864 O O   . HOH F 2 .   ? -41.21866 29.69145 45.34814  1.000 23.71271 ? 253 HOH C O   1 
HETATM 2865 O O   . HOH F 2 .   ? -46.06381 35.56618 41.63670  1.000 23.25745 ? 254 HOH C O   1 
HETATM 2866 O O   . HOH F 2 .   ? -24.601   46.014   20.514    1.000 41.62849 ? 255 HOH C O   1 
HETATM 2867 O O   . HOH F 2 .   ? -26.66707 36.19237 31.30976  1.000 35.24025 ? 256 HOH C O   1 
HETATM 2868 O O   . HOH F 2 .   ? -33.07337 18.16543 43.70388  1.000 38.37427 ? 257 HOH C O   1 
HETATM 2869 O O   . HOH F 2 .   ? -27.03791 43.52778 39.02975  1.000 38.91219 ? 258 HOH C O   1 
HETATM 2870 O O   . HOH F 2 .   ? -32.29752 33.79507 24.18195  1.000 43.08798 ? 259 HOH C O   1 
HETATM 2871 O O   . HOH F 2 .   ? -44.51654 52.37187 31.93899  1.000 33.38898 ? 260 HOH C O   1 
HETATM 2872 O O   . HOH F 2 .   ? -39.11488 14.06419 47.71852  1.000 33.51552 ? 261 HOH C O   1 
HETATM 2873 O O   . HOH F 2 .   ? -38.81152 40.35822 46.91275  0.50  44.52872 ? 262 HOH C O   1 
HETATM 2874 O O   . HOH F 2 .   ? -47.449   23.506   37.869    1.000 23.71425 ? 263 HOH C O   1 
HETATM 2875 O O   . HOH F 2 .   ? -54.393   39.063   30.006    1.000 39.71986 ? 264 HOH C O   1 
HETATM 2876 O O   . HOH F 2 .   ? -51.77997 46.72460 28.83430  1.000 37.63249 ? 265 HOH C O   1 
HETATM 2877 O O   . HOH F 2 .   ? -25.11689 31.49256 30.91026  1.000 46.46077 ? 266 HOH C O   1 
HETATM 2878 O O   . HOH F 2 .   ? -48.89900 42.83606 36.91131  1.000 21.51161 ? 267 HOH C O   1 
HETATM 2879 O O   . HOH F 2 .   ? -47.49179 37.41677 43.19394  1.000 35.70708 ? 268 HOH C O   1 
HETATM 2880 O O   . HOH F 2 .   ? -23.791   49.027   18.006    1.000 36.74757 ? 269 HOH C O   1 
HETATM 2881 O O   . HOH F 2 .   ? -29.66036 27.26037 42.27093  1.000 30.28917 ? 270 HOH C O   1 
HETATM 2882 O O   . HOH F 2 .   ? -37.95737 26.76631 43.32837  1.000 25.29305 ? 271 HOH C O   1 
HETATM 2883 O O   . HOH F 2 .   ? -46.43692 53.30495 34.42403  1.000 41.02778 ? 272 HOH C O   1 
HETATM 2884 O O   . HOH F 2 .   ? -27.05262 35.62136 36.51268  1.000 37.03808 ? 273 HOH C O   1 
HETATM 2885 O O   . HOH F 2 .   ? -29.40767 30.20973 29.01531  1.000 32.25847 ? 274 HOH C O   1 
HETATM 2886 O O   . HOH F 2 .   ? -31.90435 37.38700 41.67304  1.000 32.62150 ? 275 HOH C O   1 
HETATM 2887 O O   . HOH F 2 .   ? -43.42821 50.53080 40.65192  1.000 33.00801 ? 276 HOH C O   1 
HETATM 2888 O O   . HOH F 2 .   ? -30.62757 34.03946 44.87354  1.000 34.72842 ? 277 HOH C O   1 
HETATM 2889 O O   . HOH F 2 .   ? -34.49179 37.51660 41.29524  1.000 24.82675 ? 278 HOH C O   1 
HETATM 2890 O O   . HOH F 2 .   ? -50.22805 34.99480 29.37586  1.000 41.40393 ? 279 HOH C O   1 
HETATM 2891 O O   . HOH F 2 .   ? -47.50172 49.30045 27.00357  1.000 42.03790 ? 280 HOH C O   1 
HETATM 2892 O O   . HOH F 2 .   ? -41.35015 35.89141 48.35878  1.000 31.77229 ? 281 HOH C O   1 
HETATM 2893 O O   . HOH F 2 .   ? -37.34918 38.45564 49.02911  1.000 31.86909 ? 282 HOH C O   1 
HETATM 2894 O O   . HOH F 2 .   ? -37.88862 28.53134 28.13333  1.000 29.86094 ? 283 HOH C O   1 
HETATM 2895 O O   . HOH F 2 .   ? -53.01897 49.31603 32.86075  1.000 28.81951 ? 284 HOH C O   1 
HETATM 2896 O O   . HOH F 2 .   ? -43.74120 29.96434 28.85150  1.000 34.76569 ? 285 HOH C O   1 
HETATM 2897 O O   . HOH F 2 .   ? -40.38833 33.63910 24.24262  1.000 39.23943 ? 286 HOH C O   1 
HETATM 2898 O O   . HOH F 2 .   ? -32.81537 42.40001 23.76951  1.000 36.56298 ? 287 HOH C O   1 
HETATM 2899 O O   . HOH F 2 .   ? -32.14583 29.27042 46.30952  1.000 28.56605 ? 288 HOH C O   1 
HETATM 2900 O O   . HOH F 2 .   ? -45.41498 37.42185 27.89134  1.000 26.46680 ? 289 HOH C O   1 
HETATM 2901 O O   . HOH F 2 .   ? -49.37860 33.53429 32.90696  1.000 32.68633 ? 290 HOH C O   1 
HETATM 2902 O O   . HOH F 2 .   ? -49.82958 30.27823 38.42291  1.000 33.12249 ? 291 HOH C O   1 
HETATM 2903 O O   . HOH F 2 .   ? -49.15744 25.53416 39.44295  1.000 26.68108 ? 292 HOH C O   1 
HETATM 2904 O O   . HOH F 2 .   ? -25.38883 46.16126 31.86589  1.000 41.64030 ? 293 HOH C O   1 
HETATM 2905 O O   . HOH F 2 .   ? -45.67362 26.40018 30.44807  1.000 33.21209 ? 294 HOH C O   1 
HETATM 2906 O O   . HOH F 2 .   ? -43.45881 30.03000 31.58776  1.000 29.78339 ? 295 HOH C O   1 
HETATM 2907 O O   . HOH F 2 .   ? -25.15997 33.49459 24.52313  1.000 41.12896 ? 296 HOH C O   1 
HETATM 2908 O O   . HOH F 2 .   ? -38.67254 52.77434 36.89282  1.000 38.70416 ? 297 HOH C O   1 
HETATM 2909 O O   . HOH F 2 .   ? -27.08475 44.84890 33.96149  1.000 37.56439 ? 298 HOH C O   1 
HETATM 2910 O O   . HOH F 2 .   ? -41.39903 40.47464 44.78970  1.000 33.41101 ? 299 HOH C O   1 
HETATM 2911 O O   . HOH F 2 .   ? -49.28213 46.95670 28.45821  1.000 38.78066 ? 300 HOH C O   1 
HETATM 2912 O O   . HOH F 2 .   ? -28.75939 33.72305 25.60571  1.000 44.81848 ? 301 HOH C O   1 
HETATM 2913 O O   . HOH F 2 .   ? -20.00782 58.27137 21.58916  1.000 31.25501 ? 302 HOH C O   1 
HETATM 2914 O O   . HOH F 2 .   ? -36.66854 42.65628 21.37261  1.000 41.14202 ? 303 HOH C O   1 
HETATM 2915 O O   . HOH F 2 .   ? -24.63003 48.93516 37.86271  1.000 41.90993 ? 304 HOH C O   1 
HETATM 2916 O O   . HOH F 2 .   ? -27.00973 36.39181 46.70148  1.000 50.88555 ? 305 HOH C O   1 
HETATM 2917 O O   . HOH F 2 .   ? -35.07817 51.50648 18.04158  1.000 50.78938 ? 306 HOH C O   1 
HETATM 2918 O O   . HOH F 2 .   ? -27.00069 45.34713 22.07457  1.000 39.61328 ? 307 HOH C O   1 
HETATM 2919 O O   . HOH F 2 .   ? -43.61948 34.09051 48.39675  1.000 48.26073 ? 308 HOH C O   1 
HETATM 2920 O O   . HOH F 2 .   ? -36.14186 41.81695 44.73789  1.000 39.81749 ? 309 HOH C O   1 
HETATM 2921 O O   . HOH F 2 .   ? -51.89970 34.21070 40.19446  1.000 38.08086 ? 310 HOH C O   1 
HETATM 2922 O O   . HOH F 2 .   ? -44.64503 28.98968 45.95866  1.000 47.02026 ? 311 HOH C O   1 
HETATM 2923 O O   . HOH F 2 .   ? -50.32220 51.82794 29.21919  1.000 32.68169 ? 312 HOH C O   1 
HETATM 2924 O O   . HOH F 2 .   ? -28.08684 29.13008 36.48835  1.000 42.68677 ? 313 HOH C O   1 
HETATM 2925 O O   . HOH F 2 .   ? -23.95939 48.40903 35.21603  1.000 39.61468 ? 314 HOH C O   1 
HETATM 2926 O O   . HOH F 2 .   ? -27.71256 26.71649 40.11088  1.000 46.92668 ? 315 HOH C O   1 
HETATM 2927 O O   . HOH F 2 .   ? -25.07306 34.98395 40.54832  1.000 47.70083 ? 316 HOH C O   1 
HETATM 2928 O O   . HOH F 2 .   ? -26.67751 42.73777 36.85215  1.000 44.78372 ? 317 HOH C O   1 
HETATM 2929 O O   . HOH F 2 .   ? -38.98504 35.92066 23.34221  1.000 35.25463 ? 318 HOH C O   1 
HETATM 2930 O O   . HOH F 2 .   ? -35.66912 27.55826 28.77190  1.000 31.29210 ? 319 HOH C O   1 
HETATM 2931 O O   . HOH F 2 .   ? -44.79984 33.26049 25.50112  1.000 42.51306 ? 320 HOH C O   1 
HETATM 2932 O O   . HOH F 2 .   ? -49.15792 28.00478 39.72961  1.000 28.10842 ? 321 HOH C O   1 
HETATM 2933 O O   . HOH F 2 .   ? -41.10304 41.55629 21.04637  1.000 47.65529 ? 322 HOH C O   1 
HETATM 2934 O O   . HOH F 2 .   ? -34.38145 39.67641 43.25743  1.000 29.20359 ? 323 HOH C O   1 
HETATM 2935 O O   . HOH F 2 .   ? -33.54135 27.33906 26.86955  1.000 41.34185 ? 324 HOH C O   1 
HETATM 2936 O O   . HOH F 2 .   ? -38.69068 26.67511 26.43297  1.000 42.79170 ? 325 HOH C O   1 
HETATM 2937 O O   . HOH F 2 .   ? -52.28343 32.10236 32.85256  1.000 41.51254 ? 326 HOH C O   1 
HETATM 2938 O O   . HOH F 2 .   ? -41.39126 38.86880 46.91275  0.50  42.17073 ? 327 HOH C O   1 
HETATM 2939 O O   . HOH F 2 .   ? -43.86744 27.30633 44.65154  1.000 44.86073 ? 328 HOH C O   1 
HETATM 2940 O O   . HOH F 2 .   ? -40.12392 53.46932 38.94073  1.000 41.33835 ? 329 HOH C O   1 
HETATM 2941 O O   . HOH F 2 .   ? -23.71861 44.30785 36.16355  1.000 48.12629 ? 330 HOH C O   1 
HETATM 2942 O O   . HOH F 2 .   ? -27.02274 33.51349 34.81858  1.000 40.36149 ? 331 HOH C O   1 
HETATM 2943 O O   . HOH F 2 .   ? -30.49410 41.90876 21.65674  1.000 46.73383 ? 332 HOH C O   1 
HETATM 2944 O O   . HOH F 2 .   ? -51.82991 50.16903 30.01148  1.000 41.13553 ? 333 HOH C O   1 
HETATM 2945 O O   . HOH F 2 .   ? -37.75540 12.02926 46.67382  1.000 46.94005 ? 334 HOH C O   1 
HETATM 2946 O O   . HOH F 2 .   ? -38.26709 31.84372 23.88941  1.000 40.92487 ? 335 HOH C O   1 
HETATM 2947 O O   . HOH F 2 .   ? -24.434   45.850   17.984    1.000 40.75701 ? 336 HOH C O   1 
HETATM 2948 O O   . HOH F 2 .   ? -43.59192 30.94174 21.34394  1.000 47.71549 ? 337 HOH C O   1 
HETATM 2949 O O   . HOH F 2 .   ? -44.89785 31.78752 49.51001  1.000 45.00643 ? 338 HOH C O   1 
HETATM 2950 O O   . HOH F 2 .   ? -43.43066 51.34078 43.28530  1.000 41.84890 ? 339 HOH C O   1 
HETATM 2951 O O   . HOH F 2 .   ? -32.19655 39.34798 47.40385  1.000 40.00050 ? 340 HOH C O   1 
HETATM 2952 O O   . HOH F 2 .   ? -29.87755 33.70031 22.77581  1.000 45.35419 ? 341 HOH C O   1 
HETATM 2953 O O   . HOH F 2 .   ? -33.38267 18.83374 38.75594  1.000 43.02966 ? 342 HOH C O   1 
HETATM 2954 O O   . HOH F 2 .   ? -34.80737 43.81329 23.60647  1.000 32.23839 ? 343 HOH C O   1 
HETATM 2955 O O   . HOH F 2 .   ? -30.69030 49.38981 41.67404  1.000 38.32386 ? 344 HOH C O   1 
HETATM 2956 O O   . HOH F 2 .   ? -26.30461 37.29251 34.38797  1.000 31.82752 ? 345 HOH C O   1 
HETATM 2957 O O   . HOH F 2 .   ? -49.70180 24.35410 41.96936  1.000 37.31803 ? 346 HOH C O   1 
HETATM 2958 O O   . HOH F 2 .   ? -26.71287 29.85855 29.63903  1.000 42.26449 ? 347 HOH C O   1 
HETATM 2959 O O   . HOH F 2 .   ? -34.36372 16.81833 37.45457  1.000 44.90315 ? 348 HOH C O   1 
HETATM 2960 O O   . HOH F 2 .   ? -32.64981 21.32292 37.58692  1.000 34.87383 ? 349 HOH C O   1 
HETATM 2961 O O   . HOH F 2 .   ? -46.03655 35.61153 26.00875  1.000 36.91298 ? 350 HOH C O   1 
HETATM 2962 O O   . HOH F 2 .   ? -42.32026 32.99762 22.66460  1.000 50.97240 ? 351 HOH C O   1 
HETATM 2963 O O   . HOH F 2 .   ? -51.45443 31.96237 40.28867  1.000 36.79972 ? 352 HOH C O   1 
HETATM 2964 O O   . HOH F 2 .   ? -29.78804 22.78735 42.45546  1.000 39.48495 ? 353 HOH C O   1 
HETATM 2965 O O   . HOH F 2 .   ? -41.76935 55.54931 32.32663  1.000 43.36138 ? 354 HOH C O   1 
HETATM 2966 O O   . HOH F 2 .   ? -44.19704 25.51717 46.91275  0.50  47.42311 ? 355 HOH C O   1 
HETATM 2967 O O   . HOH F 2 .   ? -54.35700 31.38303 36.58703  0.33  30.30128 ? 356 HOH C O   1 
HETATM 2968 O O   . HOH F 2 .   ? -34.24601 12.83326 46.50572  1.000 44.90219 ? 357 HOH C O   1 
HETATM 2969 O O   . HOH F 2 .   ? -30.82070 30.61237 48.46199  1.000 45.85073 ? 358 HOH C O   1 
HETATM 2970 O O   . HOH F 2 .   ? -23.61225 36.64990 40.14267  1.000 55.28747 ? 359 HOH C O   1 
HETATM 2971 O O   . HOH F 2 .   ? -31.88628 18.26312 41.19495  1.000 41.67135 ? 360 HOH C O   1 
HETATM 2972 O O   . HOH F 2 .   ? -54.35700 31.38303 31.24493  0.33  49.60887 ? 361 HOH C O   1 
HETATM 2973 O O   . HOH F 2 .   ? -39.048   21.507   28.317    1.000 36.22078 ? 362 HOH C O   1 
# 
