data_9KY5
# 
_entry.id   9KY5 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9KY5         pdb_00009ky5 10.2210/pdb9ky5/pdb 
WWPDB D_1300054518 ?            ?                   
EMDB  EMD-62640    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-04-23 ? 
2 'EM metadata'     1 0 2025-04-23 ? 
3 'Half map'        1 0 2025-04-23 1 
4 'Half map'        1 0 2025-04-23 2 
5 Image             1 0 2025-04-23 ? 
6 'Primary map'     1 0 2025-04-23 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Half map'        repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 Image             repository 'Initial release' ? ? 
6 6 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9KY5 
_pdbx_database_status.recvd_initial_deposition_date   2024-12-08 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Structure of y+LAT2 bound with Arg' 
_pdbx_database_related.db_id          EMD-62640 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              yanrh@sustech.edu.cn 
_pdbx_contact_author.name_first         R.H. 
_pdbx_contact_author.name_last          Yan 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-7122-6547 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Yan, R.H.' 1 0000-0002-7122-6547 
'Dai, L.'   2 0009-0001-0330-7994 
'Zhang, T.' 3 0009-0003-0124-6758 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Structure of y+LAT2 bound with Arg' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Yan, R.H.' 1 0000-0002-7122-6547 
primary 'Dai, L.'   2 0009-0001-0330-7994 
primary 'Zhang, T.' 3 0009-0003-0124-6758 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Y+L amino acid transporter 2'              58934.102 1 ? ? ? ? 
2 polymer     man 'Amino acid transporter heavy chain SLC3A2' 69837.523 1 ? ? ? ? 
3 non-polymer syn ARGININE                                    175.209   1 ? ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'Cationic amino acid transporter,y+ system,Solute carrier family 7 member 6,y(+)L-type amino acid transporter 2,Y+LAT2,y+LAT-2' 
2 
;4F2 cell-surface antigen heavy chain,4F2hc,4F2 heavy chain antigen,Lymphocyte activation antigen 4F2 large subunit,Solute carrier family 3 member 2
;
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;DYKDDDDKSGPDEVDASGRMEAREPGRPTPTYHLVPNTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGS
GIFVSPKGVLVHTASYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEPTGQA
IIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEH
FQDAFEGSSWDMGNLSLALYSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSS
DAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCTMALIYL
IVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCICSVFLVIVPLFTDTINSLIGIGIALSG
VPFYFMGVYLPESRRPLFIRNVLAAITRGTQQLCFCVLTELDVAEEKKDERKTD
;
;DYKDDDDKSGPDEVDASGRMEAREPGRPTPTYHLVPNTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGS
GIFVSPKGVLVHTASYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEPTGQA
IIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEH
FQDAFEGSSWDMGNLSLALYSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSS
DAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCTMALIYL
IVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCICSVFLVIVPLFTDTINSLIGIGIALSG
VPFYFMGVYLPESRRPLFIRNVLAAITRGTQQLCFCVLTELDVAEEKKDERKTD
;
A ? 
2 'polypeptide(L)' no no 
;HHHHHHHHHHSGRELQPPEASIAVVSIPRQLPGSHSEAGVQGLSAGDDSELGSHCVAQTGLELLASGDPLPSASQNAEMI
ETGSDCVTQAGLQLLASSDPPALASKNAEVTGTMSQDTEVDMKEVELNELEPEKQPMNAASGAAMSLAGAEKNGLVKIKV
AEDEAEAAAAAKFTGLSKEELLKVAGSPGWVRTRWALLLLFWLGWLGMLAGAVVIIVRAPRCRELPAQKWWHTGALYRIG
DLQAFQGHGAGNLAGLKGRLDYLSSLKVKGLVLGPIHKNQKDDVAQTDLLQIDPNFGSKEDFDSLLQSAKKKSIRVILDL
TPNYRGENSWFSTQVDTVATKVKDALEFWLQAGVDGFQVRDIENLKDASSFLAEWQNITKGFSEDRLLIAGTNSSDLQQI
LSLLESNKDLLLTSSYLSDSGSTGEHTKSLVTQYLNATGNRWCSWSLSQARLLTSFLPAQLLRLYQLMLFTLPGTPVFSY
GDEIGLDAAALPGQPMEAPVMLWDESSFPDIPGAVSANMTVKGQSEDPGSLLSLFRRLSDQRSKERSLLHGDFHAFSAGP
GLFSYIRHWDQNERFLVVLNFGDVGLSAGLQASDLPASASLPAKADLLLSTQPGREEGSPLELERLKLEPHEGLLLRFPY
AATGA
;
;HHHHHHHHHHSGRELQPPEASIAVVSIPRQLPGSHSEAGVQGLSAGDDSELGSHCVAQTGLELLASGDPLPSASQNAEMI
ETGSDCVTQAGLQLLASSDPPALASKNAEVTGTMSQDTEVDMKEVELNELEPEKQPMNAASGAAMSLAGAEKNGLVKIKV
AEDEAEAAAAAKFTGLSKEELLKVAGSPGWVRTRWALLLLFWLGWLGMLAGAVVIIVRAPRCRELPAQKWWHTGALYRIG
DLQAFQGHGAGNLAGLKGRLDYLSSLKVKGLVLGPIHKNQKDDVAQTDLLQIDPNFGSKEDFDSLLQSAKKKSIRVILDL
TPNYRGENSWFSTQVDTVATKVKDALEFWLQAGVDGFQVRDIENLKDASSFLAEWQNITKGFSEDRLLIAGTNSSDLQQI
LSLLESNKDLLLTSSYLSDSGSTGEHTKSLVTQYLNATGNRWCSWSLSQARLLTSFLPAQLLRLYQLMLFTLPGTPVFSY
GDEIGLDAAALPGQPMEAPVMLWDESSFPDIPGAVSANMTVKGQSEDPGSLLSLFRRLSDQRSKERSLLHGDFHAFSAGP
GLFSYIRHWDQNERFLVVLNFGDVGLSAGLQASDLPASASLPAKADLLLSTQPGREEGSPLELERLKLEPHEGLLLRFPY
AATGA
;
B ? 
# 
_pdbx_entity_nonpoly.entity_id   3 
_pdbx_entity_nonpoly.name        ARGININE 
_pdbx_entity_nonpoly.comp_id     ARG 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   ASP n 
1 2   TYR n 
1 3   LYS n 
1 4   ASP n 
1 5   ASP n 
1 6   ASP n 
1 7   ASP n 
1 8   LYS n 
1 9   SER n 
1 10  GLY n 
1 11  PRO n 
1 12  ASP n 
1 13  GLU n 
1 14  VAL n 
1 15  ASP n 
1 16  ALA n 
1 17  SER n 
1 18  GLY n 
1 19  ARG n 
1 20  MET n 
1 21  GLU n 
1 22  ALA n 
1 23  ARG n 
1 24  GLU n 
1 25  PRO n 
1 26  GLY n 
1 27  ARG n 
1 28  PRO n 
1 29  THR n 
1 30  PRO n 
1 31  THR n 
1 32  TYR n 
1 33  HIS n 
1 34  LEU n 
1 35  VAL n 
1 36  PRO n 
1 37  ASN n 
1 38  THR n 
1 39  SER n 
1 40  GLN n 
1 41  SER n 
1 42  GLN n 
1 43  VAL n 
1 44  GLU n 
1 45  GLU n 
1 46  ASP n 
1 47  VAL n 
1 48  SER n 
1 49  SER n 
1 50  PRO n 
1 51  PRO n 
1 52  GLN n 
1 53  ARG n 
1 54  SER n 
1 55  SER n 
1 56  GLU n 
1 57  THR n 
1 58  MET n 
1 59  GLN n 
1 60  LEU n 
1 61  LYS n 
1 62  LYS n 
1 63  GLU n 
1 64  ILE n 
1 65  SER n 
1 66  LEU n 
1 67  LEU n 
1 68  ASN n 
1 69  GLY n 
1 70  VAL n 
1 71  SER n 
1 72  LEU n 
1 73  VAL n 
1 74  VAL n 
1 75  GLY n 
1 76  ASN n 
1 77  MET n 
1 78  ILE n 
1 79  GLY n 
1 80  SER n 
1 81  GLY n 
1 82  ILE n 
1 83  PHE n 
1 84  VAL n 
1 85  SER n 
1 86  PRO n 
1 87  LYS n 
1 88  GLY n 
1 89  VAL n 
1 90  LEU n 
1 91  VAL n 
1 92  HIS n 
1 93  THR n 
1 94  ALA n 
1 95  SER n 
1 96  TYR n 
1 97  GLY n 
1 98  MET n 
1 99  SER n 
1 100 LEU n 
1 101 ILE n 
1 102 VAL n 
1 103 TRP n 
1 104 ALA n 
1 105 ILE n 
1 106 GLY n 
1 107 GLY n 
1 108 LEU n 
1 109 PHE n 
1 110 SER n 
1 111 VAL n 
1 112 VAL n 
1 113 GLY n 
1 114 ALA n 
1 115 LEU n 
1 116 CYS n 
1 117 TYR n 
1 118 ALA n 
1 119 GLU n 
1 120 LEU n 
1 121 GLY n 
1 122 THR n 
1 123 THR n 
1 124 ILE n 
1 125 THR n 
1 126 LYS n 
1 127 SER n 
1 128 GLY n 
1 129 ALA n 
1 130 SER n 
1 131 TYR n 
1 132 ALA n 
1 133 TYR n 
1 134 ILE n 
1 135 LEU n 
1 136 GLU n 
1 137 ALA n 
1 138 PHE n 
1 139 GLY n 
1 140 GLY n 
1 141 PHE n 
1 142 ILE n 
1 143 ALA n 
1 144 PHE n 
1 145 ILE n 
1 146 ARG n 
1 147 LEU n 
1 148 TRP n 
1 149 VAL n 
1 150 SER n 
1 151 LEU n 
1 152 LEU n 
1 153 VAL n 
1 154 VAL n 
1 155 GLU n 
1 156 PRO n 
1 157 THR n 
1 158 GLY n 
1 159 GLN n 
1 160 ALA n 
1 161 ILE n 
1 162 ILE n 
1 163 ALA n 
1 164 ILE n 
1 165 THR n 
1 166 PHE n 
1 167 ALA n 
1 168 ASN n 
1 169 TYR n 
1 170 ILE n 
1 171 ILE n 
1 172 GLN n 
1 173 PRO n 
1 174 SER n 
1 175 PHE n 
1 176 PRO n 
1 177 SER n 
1 178 CYS n 
1 179 ASP n 
1 180 PRO n 
1 181 PRO n 
1 182 TYR n 
1 183 LEU n 
1 184 ALA n 
1 185 CYS n 
1 186 ARG n 
1 187 LEU n 
1 188 LEU n 
1 189 ALA n 
1 190 ALA n 
1 191 ALA n 
1 192 CYS n 
1 193 ILE n 
1 194 CYS n 
1 195 LEU n 
1 196 LEU n 
1 197 THR n 
1 198 PHE n 
1 199 VAL n 
1 200 ASN n 
1 201 CYS n 
1 202 ALA n 
1 203 TYR n 
1 204 VAL n 
1 205 LYS n 
1 206 TRP n 
1 207 GLY n 
1 208 THR n 
1 209 ARG n 
1 210 VAL n 
1 211 GLN n 
1 212 ASP n 
1 213 THR n 
1 214 PHE n 
1 215 THR n 
1 216 TYR n 
1 217 ALA n 
1 218 LYS n 
1 219 VAL n 
1 220 VAL n 
1 221 ALA n 
1 222 LEU n 
1 223 ILE n 
1 224 ALA n 
1 225 ILE n 
1 226 ILE n 
1 227 VAL n 
1 228 MET n 
1 229 GLY n 
1 230 LEU n 
1 231 VAL n 
1 232 LYS n 
1 233 LEU n 
1 234 CYS n 
1 235 GLN n 
1 236 GLY n 
1 237 HIS n 
1 238 SER n 
1 239 GLU n 
1 240 HIS n 
1 241 PHE n 
1 242 GLN n 
1 243 ASP n 
1 244 ALA n 
1 245 PHE n 
1 246 GLU n 
1 247 GLY n 
1 248 SER n 
1 249 SER n 
1 250 TRP n 
1 251 ASP n 
1 252 MET n 
1 253 GLY n 
1 254 ASN n 
1 255 LEU n 
1 256 SER n 
1 257 LEU n 
1 258 ALA n 
1 259 LEU n 
1 260 TYR n 
1 261 SER n 
1 262 ALA n 
1 263 LEU n 
1 264 PHE n 
1 265 SER n 
1 266 TYR n 
1 267 SER n 
1 268 GLY n 
1 269 TRP n 
1 270 ASP n 
1 271 THR n 
1 272 LEU n 
1 273 ASN n 
1 274 PHE n 
1 275 VAL n 
1 276 THR n 
1 277 GLU n 
1 278 GLU n 
1 279 ILE n 
1 280 LYS n 
1 281 ASN n 
1 282 PRO n 
1 283 GLU n 
1 284 ARG n 
1 285 ASN n 
1 286 LEU n 
1 287 PRO n 
1 288 LEU n 
1 289 ALA n 
1 290 ILE n 
1 291 GLY n 
1 292 ILE n 
1 293 SER n 
1 294 MET n 
1 295 PRO n 
1 296 ILE n 
1 297 VAL n 
1 298 THR n 
1 299 LEU n 
1 300 ILE n 
1 301 TYR n 
1 302 ILE n 
1 303 LEU n 
1 304 THR n 
1 305 ASN n 
1 306 VAL n 
1 307 ALA n 
1 308 TYR n 
1 309 TYR n 
1 310 THR n 
1 311 VAL n 
1 312 LEU n 
1 313 ASN n 
1 314 ILE n 
1 315 SER n 
1 316 ASP n 
1 317 VAL n 
1 318 LEU n 
1 319 SER n 
1 320 SER n 
1 321 ASP n 
1 322 ALA n 
1 323 VAL n 
1 324 ALA n 
1 325 VAL n 
1 326 THR n 
1 327 PHE n 
1 328 ALA n 
1 329 ASP n 
1 330 GLN n 
1 331 THR n 
1 332 PHE n 
1 333 GLY n 
1 334 MET n 
1 335 PHE n 
1 336 SER n 
1 337 TRP n 
1 338 THR n 
1 339 ILE n 
1 340 PRO n 
1 341 ILE n 
1 342 ALA n 
1 343 VAL n 
1 344 ALA n 
1 345 LEU n 
1 346 SER n 
1 347 CYS n 
1 348 PHE n 
1 349 GLY n 
1 350 GLY n 
1 351 LEU n 
1 352 ASN n 
1 353 ALA n 
1 354 SER n 
1 355 ILE n 
1 356 PHE n 
1 357 ALA n 
1 358 SER n 
1 359 SER n 
1 360 ARG n 
1 361 LEU n 
1 362 PHE n 
1 363 PHE n 
1 364 VAL n 
1 365 GLY n 
1 366 SER n 
1 367 ARG n 
1 368 GLU n 
1 369 GLY n 
1 370 HIS n 
1 371 LEU n 
1 372 PRO n 
1 373 ASP n 
1 374 LEU n 
1 375 LEU n 
1 376 SER n 
1 377 MET n 
1 378 ILE n 
1 379 HIS n 
1 380 ILE n 
1 381 GLU n 
1 382 ARG n 
1 383 PHE n 
1 384 THR n 
1 385 PRO n 
1 386 ILE n 
1 387 PRO n 
1 388 ALA n 
1 389 LEU n 
1 390 LEU n 
1 391 PHE n 
1 392 ASN n 
1 393 CYS n 
1 394 THR n 
1 395 MET n 
1 396 ALA n 
1 397 LEU n 
1 398 ILE n 
1 399 TYR n 
1 400 LEU n 
1 401 ILE n 
1 402 VAL n 
1 403 GLU n 
1 404 ASP n 
1 405 VAL n 
1 406 PHE n 
1 407 GLN n 
1 408 LEU n 
1 409 ILE n 
1 410 ASN n 
1 411 TYR n 
1 412 PHE n 
1 413 SER n 
1 414 PHE n 
1 415 SER n 
1 416 TYR n 
1 417 TRP n 
1 418 PHE n 
1 419 PHE n 
1 420 VAL n 
1 421 GLY n 
1 422 LEU n 
1 423 SER n 
1 424 VAL n 
1 425 VAL n 
1 426 GLY n 
1 427 GLN n 
1 428 LEU n 
1 429 TYR n 
1 430 LEU n 
1 431 ARG n 
1 432 TRP n 
1 433 LYS n 
1 434 GLU n 
1 435 PRO n 
1 436 LYS n 
1 437 ARG n 
1 438 PRO n 
1 439 ARG n 
1 440 PRO n 
1 441 LEU n 
1 442 LYS n 
1 443 LEU n 
1 444 SER n 
1 445 VAL n 
1 446 PHE n 
1 447 PHE n 
1 448 PRO n 
1 449 ILE n 
1 450 VAL n 
1 451 PHE n 
1 452 CYS n 
1 453 ILE n 
1 454 CYS n 
1 455 SER n 
1 456 VAL n 
1 457 PHE n 
1 458 LEU n 
1 459 VAL n 
1 460 ILE n 
1 461 VAL n 
1 462 PRO n 
1 463 LEU n 
1 464 PHE n 
1 465 THR n 
1 466 ASP n 
1 467 THR n 
1 468 ILE n 
1 469 ASN n 
1 470 SER n 
1 471 LEU n 
1 472 ILE n 
1 473 GLY n 
1 474 ILE n 
1 475 GLY n 
1 476 ILE n 
1 477 ALA n 
1 478 LEU n 
1 479 SER n 
1 480 GLY n 
1 481 VAL n 
1 482 PRO n 
1 483 PHE n 
1 484 TYR n 
1 485 PHE n 
1 486 MET n 
1 487 GLY n 
1 488 VAL n 
1 489 TYR n 
1 490 LEU n 
1 491 PRO n 
1 492 GLU n 
1 493 SER n 
1 494 ARG n 
1 495 ARG n 
1 496 PRO n 
1 497 LEU n 
1 498 PHE n 
1 499 ILE n 
1 500 ARG n 
1 501 ASN n 
1 502 VAL n 
1 503 LEU n 
1 504 ALA n 
1 505 ALA n 
1 506 ILE n 
1 507 THR n 
1 508 ARG n 
1 509 GLY n 
1 510 THR n 
1 511 GLN n 
1 512 GLN n 
1 513 LEU n 
1 514 CYS n 
1 515 PHE n 
1 516 CYS n 
1 517 VAL n 
1 518 LEU n 
1 519 THR n 
1 520 GLU n 
1 521 LEU n 
1 522 ASP n 
1 523 VAL n 
1 524 ALA n 
1 525 GLU n 
1 526 GLU n 
1 527 LYS n 
1 528 LYS n 
1 529 ASP n 
1 530 GLU n 
1 531 ARG n 
1 532 LYS n 
1 533 THR n 
1 534 ASP n 
2 1   HIS n 
2 2   HIS n 
2 3   HIS n 
2 4   HIS n 
2 5   HIS n 
2 6   HIS n 
2 7   HIS n 
2 8   HIS n 
2 9   HIS n 
2 10  HIS n 
2 11  SER n 
2 12  GLY n 
2 13  ARG n 
2 14  GLU n 
2 15  LEU n 
2 16  GLN n 
2 17  PRO n 
2 18  PRO n 
2 19  GLU n 
2 20  ALA n 
2 21  SER n 
2 22  ILE n 
2 23  ALA n 
2 24  VAL n 
2 25  VAL n 
2 26  SER n 
2 27  ILE n 
2 28  PRO n 
2 29  ARG n 
2 30  GLN n 
2 31  LEU n 
2 32  PRO n 
2 33  GLY n 
2 34  SER n 
2 35  HIS n 
2 36  SER n 
2 37  GLU n 
2 38  ALA n 
2 39  GLY n 
2 40  VAL n 
2 41  GLN n 
2 42  GLY n 
2 43  LEU n 
2 44  SER n 
2 45  ALA n 
2 46  GLY n 
2 47  ASP n 
2 48  ASP n 
2 49  SER n 
2 50  GLU n 
2 51  LEU n 
2 52  GLY n 
2 53  SER n 
2 54  HIS n 
2 55  CYS n 
2 56  VAL n 
2 57  ALA n 
2 58  GLN n 
2 59  THR n 
2 60  GLY n 
2 61  LEU n 
2 62  GLU n 
2 63  LEU n 
2 64  LEU n 
2 65  ALA n 
2 66  SER n 
2 67  GLY n 
2 68  ASP n 
2 69  PRO n 
2 70  LEU n 
2 71  PRO n 
2 72  SER n 
2 73  ALA n 
2 74  SER n 
2 75  GLN n 
2 76  ASN n 
2 77  ALA n 
2 78  GLU n 
2 79  MET n 
2 80  ILE n 
2 81  GLU n 
2 82  THR n 
2 83  GLY n 
2 84  SER n 
2 85  ASP n 
2 86  CYS n 
2 87  VAL n 
2 88  THR n 
2 89  GLN n 
2 90  ALA n 
2 91  GLY n 
2 92  LEU n 
2 93  GLN n 
2 94  LEU n 
2 95  LEU n 
2 96  ALA n 
2 97  SER n 
2 98  SER n 
2 99  ASP n 
2 100 PRO n 
2 101 PRO n 
2 102 ALA n 
2 103 LEU n 
2 104 ALA n 
2 105 SER n 
2 106 LYS n 
2 107 ASN n 
2 108 ALA n 
2 109 GLU n 
2 110 VAL n 
2 111 THR n 
2 112 GLY n 
2 113 THR n 
2 114 MET n 
2 115 SER n 
2 116 GLN n 
2 117 ASP n 
2 118 THR n 
2 119 GLU n 
2 120 VAL n 
2 121 ASP n 
2 122 MET n 
2 123 LYS n 
2 124 GLU n 
2 125 VAL n 
2 126 GLU n 
2 127 LEU n 
2 128 ASN n 
2 129 GLU n 
2 130 LEU n 
2 131 GLU n 
2 132 PRO n 
2 133 GLU n 
2 134 LYS n 
2 135 GLN n 
2 136 PRO n 
2 137 MET n 
2 138 ASN n 
2 139 ALA n 
2 140 ALA n 
2 141 SER n 
2 142 GLY n 
2 143 ALA n 
2 144 ALA n 
2 145 MET n 
2 146 SER n 
2 147 LEU n 
2 148 ALA n 
2 149 GLY n 
2 150 ALA n 
2 151 GLU n 
2 152 LYS n 
2 153 ASN n 
2 154 GLY n 
2 155 LEU n 
2 156 VAL n 
2 157 LYS n 
2 158 ILE n 
2 159 LYS n 
2 160 VAL n 
2 161 ALA n 
2 162 GLU n 
2 163 ASP n 
2 164 GLU n 
2 165 ALA n 
2 166 GLU n 
2 167 ALA n 
2 168 ALA n 
2 169 ALA n 
2 170 ALA n 
2 171 ALA n 
2 172 LYS n 
2 173 PHE n 
2 174 THR n 
2 175 GLY n 
2 176 LEU n 
2 177 SER n 
2 178 LYS n 
2 179 GLU n 
2 180 GLU n 
2 181 LEU n 
2 182 LEU n 
2 183 LYS n 
2 184 VAL n 
2 185 ALA n 
2 186 GLY n 
2 187 SER n 
2 188 PRO n 
2 189 GLY n 
2 190 TRP n 
2 191 VAL n 
2 192 ARG n 
2 193 THR n 
2 194 ARG n 
2 195 TRP n 
2 196 ALA n 
2 197 LEU n 
2 198 LEU n 
2 199 LEU n 
2 200 LEU n 
2 201 PHE n 
2 202 TRP n 
2 203 LEU n 
2 204 GLY n 
2 205 TRP n 
2 206 LEU n 
2 207 GLY n 
2 208 MET n 
2 209 LEU n 
2 210 ALA n 
2 211 GLY n 
2 212 ALA n 
2 213 VAL n 
2 214 VAL n 
2 215 ILE n 
2 216 ILE n 
2 217 VAL n 
2 218 ARG n 
2 219 ALA n 
2 220 PRO n 
2 221 ARG n 
2 222 CYS n 
2 223 ARG n 
2 224 GLU n 
2 225 LEU n 
2 226 PRO n 
2 227 ALA n 
2 228 GLN n 
2 229 LYS n 
2 230 TRP n 
2 231 TRP n 
2 232 HIS n 
2 233 THR n 
2 234 GLY n 
2 235 ALA n 
2 236 LEU n 
2 237 TYR n 
2 238 ARG n 
2 239 ILE n 
2 240 GLY n 
2 241 ASP n 
2 242 LEU n 
2 243 GLN n 
2 244 ALA n 
2 245 PHE n 
2 246 GLN n 
2 247 GLY n 
2 248 HIS n 
2 249 GLY n 
2 250 ALA n 
2 251 GLY n 
2 252 ASN n 
2 253 LEU n 
2 254 ALA n 
2 255 GLY n 
2 256 LEU n 
2 257 LYS n 
2 258 GLY n 
2 259 ARG n 
2 260 LEU n 
2 261 ASP n 
2 262 TYR n 
2 263 LEU n 
2 264 SER n 
2 265 SER n 
2 266 LEU n 
2 267 LYS n 
2 268 VAL n 
2 269 LYS n 
2 270 GLY n 
2 271 LEU n 
2 272 VAL n 
2 273 LEU n 
2 274 GLY n 
2 275 PRO n 
2 276 ILE n 
2 277 HIS n 
2 278 LYS n 
2 279 ASN n 
2 280 GLN n 
2 281 LYS n 
2 282 ASP n 
2 283 ASP n 
2 284 VAL n 
2 285 ALA n 
2 286 GLN n 
2 287 THR n 
2 288 ASP n 
2 289 LEU n 
2 290 LEU n 
2 291 GLN n 
2 292 ILE n 
2 293 ASP n 
2 294 PRO n 
2 295 ASN n 
2 296 PHE n 
2 297 GLY n 
2 298 SER n 
2 299 LYS n 
2 300 GLU n 
2 301 ASP n 
2 302 PHE n 
2 303 ASP n 
2 304 SER n 
2 305 LEU n 
2 306 LEU n 
2 307 GLN n 
2 308 SER n 
2 309 ALA n 
2 310 LYS n 
2 311 LYS n 
2 312 LYS n 
2 313 SER n 
2 314 ILE n 
2 315 ARG n 
2 316 VAL n 
2 317 ILE n 
2 318 LEU n 
2 319 ASP n 
2 320 LEU n 
2 321 THR n 
2 322 PRO n 
2 323 ASN n 
2 324 TYR n 
2 325 ARG n 
2 326 GLY n 
2 327 GLU n 
2 328 ASN n 
2 329 SER n 
2 330 TRP n 
2 331 PHE n 
2 332 SER n 
2 333 THR n 
2 334 GLN n 
2 335 VAL n 
2 336 ASP n 
2 337 THR n 
2 338 VAL n 
2 339 ALA n 
2 340 THR n 
2 341 LYS n 
2 342 VAL n 
2 343 LYS n 
2 344 ASP n 
2 345 ALA n 
2 346 LEU n 
2 347 GLU n 
2 348 PHE n 
2 349 TRP n 
2 350 LEU n 
2 351 GLN n 
2 352 ALA n 
2 353 GLY n 
2 354 VAL n 
2 355 ASP n 
2 356 GLY n 
2 357 PHE n 
2 358 GLN n 
2 359 VAL n 
2 360 ARG n 
2 361 ASP n 
2 362 ILE n 
2 363 GLU n 
2 364 ASN n 
2 365 LEU n 
2 366 LYS n 
2 367 ASP n 
2 368 ALA n 
2 369 SER n 
2 370 SER n 
2 371 PHE n 
2 372 LEU n 
2 373 ALA n 
2 374 GLU n 
2 375 TRP n 
2 376 GLN n 
2 377 ASN n 
2 378 ILE n 
2 379 THR n 
2 380 LYS n 
2 381 GLY n 
2 382 PHE n 
2 383 SER n 
2 384 GLU n 
2 385 ASP n 
2 386 ARG n 
2 387 LEU n 
2 388 LEU n 
2 389 ILE n 
2 390 ALA n 
2 391 GLY n 
2 392 THR n 
2 393 ASN n 
2 394 SER n 
2 395 SER n 
2 396 ASP n 
2 397 LEU n 
2 398 GLN n 
2 399 GLN n 
2 400 ILE n 
2 401 LEU n 
2 402 SER n 
2 403 LEU n 
2 404 LEU n 
2 405 GLU n 
2 406 SER n 
2 407 ASN n 
2 408 LYS n 
2 409 ASP n 
2 410 LEU n 
2 411 LEU n 
2 412 LEU n 
2 413 THR n 
2 414 SER n 
2 415 SER n 
2 416 TYR n 
2 417 LEU n 
2 418 SER n 
2 419 ASP n 
2 420 SER n 
2 421 GLY n 
2 422 SER n 
2 423 THR n 
2 424 GLY n 
2 425 GLU n 
2 426 HIS n 
2 427 THR n 
2 428 LYS n 
2 429 SER n 
2 430 LEU n 
2 431 VAL n 
2 432 THR n 
2 433 GLN n 
2 434 TYR n 
2 435 LEU n 
2 436 ASN n 
2 437 ALA n 
2 438 THR n 
2 439 GLY n 
2 440 ASN n 
2 441 ARG n 
2 442 TRP n 
2 443 CYS n 
2 444 SER n 
2 445 TRP n 
2 446 SER n 
2 447 LEU n 
2 448 SER n 
2 449 GLN n 
2 450 ALA n 
2 451 ARG n 
2 452 LEU n 
2 453 LEU n 
2 454 THR n 
2 455 SER n 
2 456 PHE n 
2 457 LEU n 
2 458 PRO n 
2 459 ALA n 
2 460 GLN n 
2 461 LEU n 
2 462 LEU n 
2 463 ARG n 
2 464 LEU n 
2 465 TYR n 
2 466 GLN n 
2 467 LEU n 
2 468 MET n 
2 469 LEU n 
2 470 PHE n 
2 471 THR n 
2 472 LEU n 
2 473 PRO n 
2 474 GLY n 
2 475 THR n 
2 476 PRO n 
2 477 VAL n 
2 478 PHE n 
2 479 SER n 
2 480 TYR n 
2 481 GLY n 
2 482 ASP n 
2 483 GLU n 
2 484 ILE n 
2 485 GLY n 
2 486 LEU n 
2 487 ASP n 
2 488 ALA n 
2 489 ALA n 
2 490 ALA n 
2 491 LEU n 
2 492 PRO n 
2 493 GLY n 
2 494 GLN n 
2 495 PRO n 
2 496 MET n 
2 497 GLU n 
2 498 ALA n 
2 499 PRO n 
2 500 VAL n 
2 501 MET n 
2 502 LEU n 
2 503 TRP n 
2 504 ASP n 
2 505 GLU n 
2 506 SER n 
2 507 SER n 
2 508 PHE n 
2 509 PRO n 
2 510 ASP n 
2 511 ILE n 
2 512 PRO n 
2 513 GLY n 
2 514 ALA n 
2 515 VAL n 
2 516 SER n 
2 517 ALA n 
2 518 ASN n 
2 519 MET n 
2 520 THR n 
2 521 VAL n 
2 522 LYS n 
2 523 GLY n 
2 524 GLN n 
2 525 SER n 
2 526 GLU n 
2 527 ASP n 
2 528 PRO n 
2 529 GLY n 
2 530 SER n 
2 531 LEU n 
2 532 LEU n 
2 533 SER n 
2 534 LEU n 
2 535 PHE n 
2 536 ARG n 
2 537 ARG n 
2 538 LEU n 
2 539 SER n 
2 540 ASP n 
2 541 GLN n 
2 542 ARG n 
2 543 SER n 
2 544 LYS n 
2 545 GLU n 
2 546 ARG n 
2 547 SER n 
2 548 LEU n 
2 549 LEU n 
2 550 HIS n 
2 551 GLY n 
2 552 ASP n 
2 553 PHE n 
2 554 HIS n 
2 555 ALA n 
2 556 PHE n 
2 557 SER n 
2 558 ALA n 
2 559 GLY n 
2 560 PRO n 
2 561 GLY n 
2 562 LEU n 
2 563 PHE n 
2 564 SER n 
2 565 TYR n 
2 566 ILE n 
2 567 ARG n 
2 568 HIS n 
2 569 TRP n 
2 570 ASP n 
2 571 GLN n 
2 572 ASN n 
2 573 GLU n 
2 574 ARG n 
2 575 PHE n 
2 576 LEU n 
2 577 VAL n 
2 578 VAL n 
2 579 LEU n 
2 580 ASN n 
2 581 PHE n 
2 582 GLY n 
2 583 ASP n 
2 584 VAL n 
2 585 GLY n 
2 586 LEU n 
2 587 SER n 
2 588 ALA n 
2 589 GLY n 
2 590 LEU n 
2 591 GLN n 
2 592 ALA n 
2 593 SER n 
2 594 ASP n 
2 595 LEU n 
2 596 PRO n 
2 597 ALA n 
2 598 SER n 
2 599 ALA n 
2 600 SER n 
2 601 LEU n 
2 602 PRO n 
2 603 ALA n 
2 604 LYS n 
2 605 ALA n 
2 606 ASP n 
2 607 LEU n 
2 608 LEU n 
2 609 LEU n 
2 610 SER n 
2 611 THR n 
2 612 GLN n 
2 613 PRO n 
2 614 GLY n 
2 615 ARG n 
2 616 GLU n 
2 617 GLU n 
2 618 GLY n 
2 619 SER n 
2 620 PRO n 
2 621 LEU n 
2 622 GLU n 
2 623 LEU n 
2 624 GLU n 
2 625 ARG n 
2 626 LEU n 
2 627 LYS n 
2 628 LEU n 
2 629 GLU n 
2 630 PRO n 
2 631 HIS n 
2 632 GLU n 
2 633 GLY n 
2 634 LEU n 
2 635 LEU n 
2 636 LEU n 
2 637 ARG n 
2 638 PHE n 
2 639 PRO n 
2 640 TYR n 
2 641 ALA n 
2 642 ALA n 
2 643 THR n 
2 644 GLY n 
2 645 ALA n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 534 human ? 'SLC7A6, KIAA0245' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Homo sapiens' 
9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 645 human ? 'SLC3A2, MDU1'     ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Homo sapiens' 
9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   ASP 1   -18 ?   ?   ?   A . n 
A 1 2   TYR 2   -17 ?   ?   ?   A . n 
A 1 3   LYS 3   -16 ?   ?   ?   A . n 
A 1 4   ASP 4   -15 ?   ?   ?   A . n 
A 1 5   ASP 5   -14 ?   ?   ?   A . n 
A 1 6   ASP 6   -13 ?   ?   ?   A . n 
A 1 7   ASP 7   -12 ?   ?   ?   A . n 
A 1 8   LYS 8   -11 ?   ?   ?   A . n 
A 1 9   SER 9   -10 ?   ?   ?   A . n 
A 1 10  GLY 10  -9  ?   ?   ?   A . n 
A 1 11  PRO 11  -8  ?   ?   ?   A . n 
A 1 12  ASP 12  -7  ?   ?   ?   A . n 
A 1 13  GLU 13  -6  ?   ?   ?   A . n 
A 1 14  VAL 14  -5  ?   ?   ?   A . n 
A 1 15  ASP 15  -4  ?   ?   ?   A . n 
A 1 16  ALA 16  -3  ?   ?   ?   A . n 
A 1 17  SER 17  -2  ?   ?   ?   A . n 
A 1 18  GLY 18  -1  ?   ?   ?   A . n 
A 1 19  ARG 19  0   ?   ?   ?   A . n 
A 1 20  MET 20  1   ?   ?   ?   A . n 
A 1 21  GLU 21  2   ?   ?   ?   A . n 
A 1 22  ALA 22  3   ?   ?   ?   A . n 
A 1 23  ARG 23  4   ?   ?   ?   A . n 
A 1 24  GLU 24  5   ?   ?   ?   A . n 
A 1 25  PRO 25  6   ?   ?   ?   A . n 
A 1 26  GLY 26  7   ?   ?   ?   A . n 
A 1 27  ARG 27  8   ?   ?   ?   A . n 
A 1 28  PRO 28  9   ?   ?   ?   A . n 
A 1 29  THR 29  10  ?   ?   ?   A . n 
A 1 30  PRO 30  11  ?   ?   ?   A . n 
A 1 31  THR 31  12  ?   ?   ?   A . n 
A 1 32  TYR 32  13  ?   ?   ?   A . n 
A 1 33  HIS 33  14  ?   ?   ?   A . n 
A 1 34  LEU 34  15  ?   ?   ?   A . n 
A 1 35  VAL 35  16  ?   ?   ?   A . n 
A 1 36  PRO 36  17  ?   ?   ?   A . n 
A 1 37  ASN 37  18  ?   ?   ?   A . n 
A 1 38  THR 38  19  ?   ?   ?   A . n 
A 1 39  SER 39  20  ?   ?   ?   A . n 
A 1 40  GLN 40  21  ?   ?   ?   A . n 
A 1 41  SER 41  22  ?   ?   ?   A . n 
A 1 42  GLN 42  23  ?   ?   ?   A . n 
A 1 43  VAL 43  24  ?   ?   ?   A . n 
A 1 44  GLU 44  25  ?   ?   ?   A . n 
A 1 45  GLU 45  26  ?   ?   ?   A . n 
A 1 46  ASP 46  27  ?   ?   ?   A . n 
A 1 47  VAL 47  28  ?   ?   ?   A . n 
A 1 48  SER 48  29  ?   ?   ?   A . n 
A 1 49  SER 49  30  ?   ?   ?   A . n 
A 1 50  PRO 50  31  ?   ?   ?   A . n 
A 1 51  PRO 51  32  ?   ?   ?   A . n 
A 1 52  GLN 52  33  ?   ?   ?   A . n 
A 1 53  ARG 53  34  ?   ?   ?   A . n 
A 1 54  SER 54  35  ?   ?   ?   A . n 
A 1 55  SER 55  36  ?   ?   ?   A . n 
A 1 56  GLU 56  37  ?   ?   ?   A . n 
A 1 57  THR 57  38  ?   ?   ?   A . n 
A 1 58  MET 58  39  39  MET MET A . n 
A 1 59  GLN 59  40  40  GLN GLN A . n 
A 1 60  LEU 60  41  41  LEU LEU A . n 
A 1 61  LYS 61  42  42  LYS LYS A . n 
A 1 62  LYS 62  43  43  LYS LYS A . n 
A 1 63  GLU 63  44  44  GLU GLU A . n 
A 1 64  ILE 64  45  45  ILE ILE A . n 
A 1 65  SER 65  46  46  SER SER A . n 
A 1 66  LEU 66  47  47  LEU LEU A . n 
A 1 67  LEU 67  48  48  LEU LEU A . n 
A 1 68  ASN 68  49  49  ASN ASN A . n 
A 1 69  GLY 69  50  50  GLY GLY A . n 
A 1 70  VAL 70  51  51  VAL VAL A . n 
A 1 71  SER 71  52  52  SER SER A . n 
A 1 72  LEU 72  53  53  LEU LEU A . n 
A 1 73  VAL 73  54  54  VAL VAL A . n 
A 1 74  VAL 74  55  55  VAL VAL A . n 
A 1 75  GLY 75  56  56  GLY GLY A . n 
A 1 76  ASN 76  57  57  ASN ASN A . n 
A 1 77  MET 77  58  58  MET MET A . n 
A 1 78  ILE 78  59  59  ILE ILE A . n 
A 1 79  GLY 79  60  60  GLY GLY A . n 
A 1 80  SER 80  61  61  SER SER A . n 
A 1 81  GLY 81  62  62  GLY GLY A . n 
A 1 82  ILE 82  63  63  ILE ILE A . n 
A 1 83  PHE 83  64  64  PHE PHE A . n 
A 1 84  VAL 84  65  65  VAL VAL A . n 
A 1 85  SER 85  66  66  SER SER A . n 
A 1 86  PRO 86  67  67  PRO PRO A . n 
A 1 87  LYS 87  68  68  LYS LYS A . n 
A 1 88  GLY 88  69  69  GLY GLY A . n 
A 1 89  VAL 89  70  70  VAL VAL A . n 
A 1 90  LEU 90  71  71  LEU LEU A . n 
A 1 91  VAL 91  72  72  VAL VAL A . n 
A 1 92  HIS 92  73  73  HIS HIS A . n 
A 1 93  THR 93  74  74  THR THR A . n 
A 1 94  ALA 94  75  75  ALA ALA A . n 
A 1 95  SER 95  76  76  SER SER A . n 
A 1 96  TYR 96  77  77  TYR TYR A . n 
A 1 97  GLY 97  78  78  GLY GLY A . n 
A 1 98  MET 98  79  79  MET MET A . n 
A 1 99  SER 99  80  80  SER SER A . n 
A 1 100 LEU 100 81  81  LEU LEU A . n 
A 1 101 ILE 101 82  82  ILE ILE A . n 
A 1 102 VAL 102 83  83  VAL VAL A . n 
A 1 103 TRP 103 84  84  TRP TRP A . n 
A 1 104 ALA 104 85  85  ALA ALA A . n 
A 1 105 ILE 105 86  86  ILE ILE A . n 
A 1 106 GLY 106 87  87  GLY GLY A . n 
A 1 107 GLY 107 88  88  GLY GLY A . n 
A 1 108 LEU 108 89  89  LEU LEU A . n 
A 1 109 PHE 109 90  90  PHE PHE A . n 
A 1 110 SER 110 91  91  SER SER A . n 
A 1 111 VAL 111 92  92  VAL VAL A . n 
A 1 112 VAL 112 93  93  VAL VAL A . n 
A 1 113 GLY 113 94  94  GLY GLY A . n 
A 1 114 ALA 114 95  95  ALA ALA A . n 
A 1 115 LEU 115 96  96  LEU LEU A . n 
A 1 116 CYS 116 97  97  CYS CYS A . n 
A 1 117 TYR 117 98  98  TYR TYR A . n 
A 1 118 ALA 118 99  99  ALA ALA A . n 
A 1 119 GLU 119 100 100 GLU GLU A . n 
A 1 120 LEU 120 101 101 LEU LEU A . n 
A 1 121 GLY 121 102 102 GLY GLY A . n 
A 1 122 THR 122 103 103 THR THR A . n 
A 1 123 THR 123 104 104 THR THR A . n 
A 1 124 ILE 124 105 105 ILE ILE A . n 
A 1 125 THR 125 106 106 THR THR A . n 
A 1 126 LYS 126 107 107 LYS LYS A . n 
A 1 127 SER 127 108 108 SER SER A . n 
A 1 128 GLY 128 109 109 GLY GLY A . n 
A 1 129 ALA 129 110 110 ALA ALA A . n 
A 1 130 SER 130 111 111 SER SER A . n 
A 1 131 TYR 131 112 112 TYR TYR A . n 
A 1 132 ALA 132 113 113 ALA ALA A . n 
A 1 133 TYR 133 114 114 TYR TYR A . n 
A 1 134 ILE 134 115 115 ILE ILE A . n 
A 1 135 LEU 135 116 116 LEU LEU A . n 
A 1 136 GLU 136 117 117 GLU GLU A . n 
A 1 137 ALA 137 118 118 ALA ALA A . n 
A 1 138 PHE 138 119 119 PHE PHE A . n 
A 1 139 GLY 139 120 120 GLY GLY A . n 
A 1 140 GLY 140 121 121 GLY GLY A . n 
A 1 141 PHE 141 122 122 PHE PHE A . n 
A 1 142 ILE 142 123 123 ILE ILE A . n 
A 1 143 ALA 143 124 124 ALA ALA A . n 
A 1 144 PHE 144 125 125 PHE PHE A . n 
A 1 145 ILE 145 126 126 ILE ILE A . n 
A 1 146 ARG 146 127 127 ARG ARG A . n 
A 1 147 LEU 147 128 128 LEU LEU A . n 
A 1 148 TRP 148 129 129 TRP TRP A . n 
A 1 149 VAL 149 130 130 VAL VAL A . n 
A 1 150 SER 150 131 131 SER SER A . n 
A 1 151 LEU 151 132 132 LEU LEU A . n 
A 1 152 LEU 152 133 133 LEU LEU A . n 
A 1 153 VAL 153 134 134 VAL VAL A . n 
A 1 154 VAL 154 135 135 VAL VAL A . n 
A 1 155 GLU 155 136 136 GLU GLU A . n 
A 1 156 PRO 156 137 137 PRO PRO A . n 
A 1 157 THR 157 138 138 THR THR A . n 
A 1 158 GLY 158 139 139 GLY GLY A . n 
A 1 159 GLN 159 140 140 GLN GLN A . n 
A 1 160 ALA 160 141 141 ALA ALA A . n 
A 1 161 ILE 161 142 142 ILE ILE A . n 
A 1 162 ILE 162 143 143 ILE ILE A . n 
A 1 163 ALA 163 144 144 ALA ALA A . n 
A 1 164 ILE 164 145 145 ILE ILE A . n 
A 1 165 THR 165 146 146 THR THR A . n 
A 1 166 PHE 166 147 147 PHE PHE A . n 
A 1 167 ALA 167 148 148 ALA ALA A . n 
A 1 168 ASN 168 149 149 ASN ASN A . n 
A 1 169 TYR 169 150 150 TYR TYR A . n 
A 1 170 ILE 170 151 151 ILE ILE A . n 
A 1 171 ILE 171 152 152 ILE ILE A . n 
A 1 172 GLN 172 153 153 GLN GLN A . n 
A 1 173 PRO 173 154 154 PRO PRO A . n 
A 1 174 SER 174 155 155 SER SER A . n 
A 1 175 PHE 175 156 156 PHE PHE A . n 
A 1 176 PRO 176 157 157 PRO PRO A . n 
A 1 177 SER 177 158 158 SER SER A . n 
A 1 178 CYS 178 159 159 CYS CYS A . n 
A 1 179 ASP 179 160 160 ASP ASP A . n 
A 1 180 PRO 180 161 161 PRO PRO A . n 
A 1 181 PRO 181 162 162 PRO PRO A . n 
A 1 182 TYR 182 163 163 TYR TYR A . n 
A 1 183 LEU 183 164 164 LEU LEU A . n 
A 1 184 ALA 184 165 165 ALA ALA A . n 
A 1 185 CYS 185 166 166 CYS CYS A . n 
A 1 186 ARG 186 167 167 ARG ARG A . n 
A 1 187 LEU 187 168 168 LEU LEU A . n 
A 1 188 LEU 188 169 169 LEU LEU A . n 
A 1 189 ALA 189 170 170 ALA ALA A . n 
A 1 190 ALA 190 171 171 ALA ALA A . n 
A 1 191 ALA 191 172 172 ALA ALA A . n 
A 1 192 CYS 192 173 173 CYS CYS A . n 
A 1 193 ILE 193 174 174 ILE ILE A . n 
A 1 194 CYS 194 175 175 CYS CYS A . n 
A 1 195 LEU 195 176 176 LEU LEU A . n 
A 1 196 LEU 196 177 177 LEU LEU A . n 
A 1 197 THR 197 178 178 THR THR A . n 
A 1 198 PHE 198 179 179 PHE PHE A . n 
A 1 199 VAL 199 180 180 VAL VAL A . n 
A 1 200 ASN 200 181 181 ASN ASN A . n 
A 1 201 CYS 201 182 182 CYS CYS A . n 
A 1 202 ALA 202 183 183 ALA ALA A . n 
A 1 203 TYR 203 184 184 TYR TYR A . n 
A 1 204 VAL 204 185 185 VAL VAL A . n 
A 1 205 LYS 205 186 186 LYS LYS A . n 
A 1 206 TRP 206 187 187 TRP TRP A . n 
A 1 207 GLY 207 188 188 GLY GLY A . n 
A 1 208 THR 208 189 189 THR THR A . n 
A 1 209 ARG 209 190 190 ARG ARG A . n 
A 1 210 VAL 210 191 191 VAL VAL A . n 
A 1 211 GLN 211 192 192 GLN GLN A . n 
A 1 212 ASP 212 193 193 ASP ASP A . n 
A 1 213 THR 213 194 194 THR THR A . n 
A 1 214 PHE 214 195 195 PHE PHE A . n 
A 1 215 THR 215 196 196 THR THR A . n 
A 1 216 TYR 216 197 197 TYR TYR A . n 
A 1 217 ALA 217 198 198 ALA ALA A . n 
A 1 218 LYS 218 199 199 LYS LYS A . n 
A 1 219 VAL 219 200 200 VAL VAL A . n 
A 1 220 VAL 220 201 201 VAL VAL A . n 
A 1 221 ALA 221 202 202 ALA ALA A . n 
A 1 222 LEU 222 203 203 LEU LEU A . n 
A 1 223 ILE 223 204 204 ILE ILE A . n 
A 1 224 ALA 224 205 205 ALA ALA A . n 
A 1 225 ILE 225 206 206 ILE ILE A . n 
A 1 226 ILE 226 207 207 ILE ILE A . n 
A 1 227 VAL 227 208 208 VAL VAL A . n 
A 1 228 MET 228 209 209 MET MET A . n 
A 1 229 GLY 229 210 210 GLY GLY A . n 
A 1 230 LEU 230 211 211 LEU LEU A . n 
A 1 231 VAL 231 212 212 VAL VAL A . n 
A 1 232 LYS 232 213 213 LYS LYS A . n 
A 1 233 LEU 233 214 214 LEU LEU A . n 
A 1 234 CYS 234 215 215 CYS CYS A . n 
A 1 235 GLN 235 216 216 GLN GLN A . n 
A 1 236 GLY 236 217 217 GLY GLY A . n 
A 1 237 HIS 237 218 218 HIS HIS A . n 
A 1 238 SER 238 219 219 SER SER A . n 
A 1 239 GLU 239 220 220 GLU GLU A . n 
A 1 240 HIS 240 221 221 HIS HIS A . n 
A 1 241 PHE 241 222 222 PHE PHE A . n 
A 1 242 GLN 242 223 223 GLN GLN A . n 
A 1 243 ASP 243 224 224 ASP ASP A . n 
A 1 244 ALA 244 225 225 ALA ALA A . n 
A 1 245 PHE 245 226 226 PHE PHE A . n 
A 1 246 GLU 246 227 227 GLU GLU A . n 
A 1 247 GLY 247 228 228 GLY GLY A . n 
A 1 248 SER 248 229 229 SER SER A . n 
A 1 249 SER 249 230 230 SER SER A . n 
A 1 250 TRP 250 231 231 TRP TRP A . n 
A 1 251 ASP 251 232 232 ASP ASP A . n 
A 1 252 MET 252 233 233 MET MET A . n 
A 1 253 GLY 253 234 234 GLY GLY A . n 
A 1 254 ASN 254 235 235 ASN ASN A . n 
A 1 255 LEU 255 236 236 LEU LEU A . n 
A 1 256 SER 256 237 237 SER SER A . n 
A 1 257 LEU 257 238 238 LEU LEU A . n 
A 1 258 ALA 258 239 239 ALA ALA A . n 
A 1 259 LEU 259 240 240 LEU LEU A . n 
A 1 260 TYR 260 241 241 TYR TYR A . n 
A 1 261 SER 261 242 242 SER SER A . n 
A 1 262 ALA 262 243 243 ALA ALA A . n 
A 1 263 LEU 263 244 244 LEU LEU A . n 
A 1 264 PHE 264 245 245 PHE PHE A . n 
A 1 265 SER 265 246 246 SER SER A . n 
A 1 266 TYR 266 247 247 TYR TYR A . n 
A 1 267 SER 267 248 248 SER SER A . n 
A 1 268 GLY 268 249 249 GLY GLY A . n 
A 1 269 TRP 269 250 250 TRP TRP A . n 
A 1 270 ASP 270 251 251 ASP ASP A . n 
A 1 271 THR 271 252 252 THR THR A . n 
A 1 272 LEU 272 253 253 LEU LEU A . n 
A 1 273 ASN 273 254 254 ASN ASN A . n 
A 1 274 PHE 274 255 255 PHE PHE A . n 
A 1 275 VAL 275 256 256 VAL VAL A . n 
A 1 276 THR 276 257 257 THR THR A . n 
A 1 277 GLU 277 258 258 GLU GLU A . n 
A 1 278 GLU 278 259 259 GLU GLU A . n 
A 1 279 ILE 279 260 260 ILE ILE A . n 
A 1 280 LYS 280 261 261 LYS LYS A . n 
A 1 281 ASN 281 262 262 ASN ASN A . n 
A 1 282 PRO 282 263 263 PRO PRO A . n 
A 1 283 GLU 283 264 264 GLU GLU A . n 
A 1 284 ARG 284 265 265 ARG ARG A . n 
A 1 285 ASN 285 266 266 ASN ASN A . n 
A 1 286 LEU 286 267 267 LEU LEU A . n 
A 1 287 PRO 287 268 268 PRO PRO A . n 
A 1 288 LEU 288 269 269 LEU LEU A . n 
A 1 289 ALA 289 270 270 ALA ALA A . n 
A 1 290 ILE 290 271 271 ILE ILE A . n 
A 1 291 GLY 291 272 272 GLY GLY A . n 
A 1 292 ILE 292 273 273 ILE ILE A . n 
A 1 293 SER 293 274 274 SER SER A . n 
A 1 294 MET 294 275 275 MET MET A . n 
A 1 295 PRO 295 276 276 PRO PRO A . n 
A 1 296 ILE 296 277 277 ILE ILE A . n 
A 1 297 VAL 297 278 278 VAL VAL A . n 
A 1 298 THR 298 279 279 THR THR A . n 
A 1 299 LEU 299 280 280 LEU LEU A . n 
A 1 300 ILE 300 281 281 ILE ILE A . n 
A 1 301 TYR 301 282 282 TYR TYR A . n 
A 1 302 ILE 302 283 283 ILE ILE A . n 
A 1 303 LEU 303 284 284 LEU LEU A . n 
A 1 304 THR 304 285 285 THR THR A . n 
A 1 305 ASN 305 286 286 ASN ASN A . n 
A 1 306 VAL 306 287 287 VAL VAL A . n 
A 1 307 ALA 307 288 288 ALA ALA A . n 
A 1 308 TYR 308 289 289 TYR TYR A . n 
A 1 309 TYR 309 290 290 TYR TYR A . n 
A 1 310 THR 310 291 291 THR THR A . n 
A 1 311 VAL 311 292 292 VAL VAL A . n 
A 1 312 LEU 312 293 293 LEU LEU A . n 
A 1 313 ASN 313 294 294 ASN ASN A . n 
A 1 314 ILE 314 295 295 ILE ILE A . n 
A 1 315 SER 315 296 296 SER SER A . n 
A 1 316 ASP 316 297 297 ASP ASP A . n 
A 1 317 VAL 317 298 298 VAL VAL A . n 
A 1 318 LEU 318 299 299 LEU LEU A . n 
A 1 319 SER 319 300 300 SER SER A . n 
A 1 320 SER 320 301 301 SER SER A . n 
A 1 321 ASP 321 302 302 ASP ASP A . n 
A 1 322 ALA 322 303 303 ALA ALA A . n 
A 1 323 VAL 323 304 304 VAL VAL A . n 
A 1 324 ALA 324 305 305 ALA ALA A . n 
A 1 325 VAL 325 306 306 VAL VAL A . n 
A 1 326 THR 326 307 307 THR THR A . n 
A 1 327 PHE 327 308 308 PHE PHE A . n 
A 1 328 ALA 328 309 309 ALA ALA A . n 
A 1 329 ASP 329 310 310 ASP ASP A . n 
A 1 330 GLN 330 311 311 GLN GLN A . n 
A 1 331 THR 331 312 312 THR THR A . n 
A 1 332 PHE 332 313 313 PHE PHE A . n 
A 1 333 GLY 333 314 314 GLY GLY A . n 
A 1 334 MET 334 315 315 MET MET A . n 
A 1 335 PHE 335 316 316 PHE PHE A . n 
A 1 336 SER 336 317 317 SER SER A . n 
A 1 337 TRP 337 318 318 TRP TRP A . n 
A 1 338 THR 338 319 319 THR THR A . n 
A 1 339 ILE 339 320 320 ILE ILE A . n 
A 1 340 PRO 340 321 321 PRO PRO A . n 
A 1 341 ILE 341 322 322 ILE ILE A . n 
A 1 342 ALA 342 323 323 ALA ALA A . n 
A 1 343 VAL 343 324 324 VAL VAL A . n 
A 1 344 ALA 344 325 325 ALA ALA A . n 
A 1 345 LEU 345 326 326 LEU LEU A . n 
A 1 346 SER 346 327 327 SER SER A . n 
A 1 347 CYS 347 328 328 CYS CYS A . n 
A 1 348 PHE 348 329 329 PHE PHE A . n 
A 1 349 GLY 349 330 330 GLY GLY A . n 
A 1 350 GLY 350 331 331 GLY GLY A . n 
A 1 351 LEU 351 332 332 LEU LEU A . n 
A 1 352 ASN 352 333 333 ASN ASN A . n 
A 1 353 ALA 353 334 334 ALA ALA A . n 
A 1 354 SER 354 335 335 SER SER A . n 
A 1 355 ILE 355 336 336 ILE ILE A . n 
A 1 356 PHE 356 337 337 PHE PHE A . n 
A 1 357 ALA 357 338 338 ALA ALA A . n 
A 1 358 SER 358 339 339 SER SER A . n 
A 1 359 SER 359 340 340 SER SER A . n 
A 1 360 ARG 360 341 341 ARG ARG A . n 
A 1 361 LEU 361 342 342 LEU LEU A . n 
A 1 362 PHE 362 343 343 PHE PHE A . n 
A 1 363 PHE 363 344 344 PHE PHE A . n 
A 1 364 VAL 364 345 345 VAL VAL A . n 
A 1 365 GLY 365 346 346 GLY GLY A . n 
A 1 366 SER 366 347 347 SER SER A . n 
A 1 367 ARG 367 348 348 ARG ARG A . n 
A 1 368 GLU 368 349 349 GLU GLU A . n 
A 1 369 GLY 369 350 350 GLY GLY A . n 
A 1 370 HIS 370 351 351 HIS HIS A . n 
A 1 371 LEU 371 352 352 LEU LEU A . n 
A 1 372 PRO 372 353 353 PRO PRO A . n 
A 1 373 ASP 373 354 354 ASP ASP A . n 
A 1 374 LEU 374 355 355 LEU LEU A . n 
A 1 375 LEU 375 356 356 LEU LEU A . n 
A 1 376 SER 376 357 357 SER SER A . n 
A 1 377 MET 377 358 358 MET MET A . n 
A 1 378 ILE 378 359 359 ILE ILE A . n 
A 1 379 HIS 379 360 360 HIS HIS A . n 
A 1 380 ILE 380 361 361 ILE ILE A . n 
A 1 381 GLU 381 362 362 GLU GLU A . n 
A 1 382 ARG 382 363 363 ARG ARG A . n 
A 1 383 PHE 383 364 364 PHE PHE A . n 
A 1 384 THR 384 365 365 THR THR A . n 
A 1 385 PRO 385 366 366 PRO PRO A . n 
A 1 386 ILE 386 367 367 ILE ILE A . n 
A 1 387 PRO 387 368 368 PRO PRO A . n 
A 1 388 ALA 388 369 369 ALA ALA A . n 
A 1 389 LEU 389 370 370 LEU LEU A . n 
A 1 390 LEU 390 371 371 LEU LEU A . n 
A 1 391 PHE 391 372 372 PHE PHE A . n 
A 1 392 ASN 392 373 373 ASN ASN A . n 
A 1 393 CYS 393 374 374 CYS CYS A . n 
A 1 394 THR 394 375 375 THR THR A . n 
A 1 395 MET 395 376 376 MET MET A . n 
A 1 396 ALA 396 377 377 ALA ALA A . n 
A 1 397 LEU 397 378 378 LEU LEU A . n 
A 1 398 ILE 398 379 379 ILE ILE A . n 
A 1 399 TYR 399 380 380 TYR TYR A . n 
A 1 400 LEU 400 381 381 LEU LEU A . n 
A 1 401 ILE 401 382 382 ILE ILE A . n 
A 1 402 VAL 402 383 383 VAL VAL A . n 
A 1 403 GLU 403 384 384 GLU GLU A . n 
A 1 404 ASP 404 385 385 ASP ASP A . n 
A 1 405 VAL 405 386 386 VAL VAL A . n 
A 1 406 PHE 406 387 387 PHE PHE A . n 
A 1 407 GLN 407 388 388 GLN GLN A . n 
A 1 408 LEU 408 389 389 LEU LEU A . n 
A 1 409 ILE 409 390 390 ILE ILE A . n 
A 1 410 ASN 410 391 391 ASN ASN A . n 
A 1 411 TYR 411 392 392 TYR TYR A . n 
A 1 412 PHE 412 393 393 PHE PHE A . n 
A 1 413 SER 413 394 394 SER SER A . n 
A 1 414 PHE 414 395 395 PHE PHE A . n 
A 1 415 SER 415 396 396 SER SER A . n 
A 1 416 TYR 416 397 397 TYR TYR A . n 
A 1 417 TRP 417 398 398 TRP TRP A . n 
A 1 418 PHE 418 399 399 PHE PHE A . n 
A 1 419 PHE 419 400 400 PHE PHE A . n 
A 1 420 VAL 420 401 401 VAL VAL A . n 
A 1 421 GLY 421 402 402 GLY GLY A . n 
A 1 422 LEU 422 403 403 LEU LEU A . n 
A 1 423 SER 423 404 404 SER SER A . n 
A 1 424 VAL 424 405 405 VAL VAL A . n 
A 1 425 VAL 425 406 406 VAL VAL A . n 
A 1 426 GLY 426 407 407 GLY GLY A . n 
A 1 427 GLN 427 408 408 GLN GLN A . n 
A 1 428 LEU 428 409 409 LEU LEU A . n 
A 1 429 TYR 429 410 410 TYR TYR A . n 
A 1 430 LEU 430 411 411 LEU LEU A . n 
A 1 431 ARG 431 412 412 ARG ARG A . n 
A 1 432 TRP 432 413 413 TRP TRP A . n 
A 1 433 LYS 433 414 414 LYS LYS A . n 
A 1 434 GLU 434 415 415 GLU GLU A . n 
A 1 435 PRO 435 416 416 PRO PRO A . n 
A 1 436 LYS 436 417 417 LYS LYS A . n 
A 1 437 ARG 437 418 418 ARG ARG A . n 
A 1 438 PRO 438 419 419 PRO PRO A . n 
A 1 439 ARG 439 420 420 ARG ARG A . n 
A 1 440 PRO 440 421 421 PRO PRO A . n 
A 1 441 LEU 441 422 422 LEU LEU A . n 
A 1 442 LYS 442 423 423 LYS LYS A . n 
A 1 443 LEU 443 424 424 LEU LEU A . n 
A 1 444 SER 444 425 425 SER SER A . n 
A 1 445 VAL 445 426 426 VAL VAL A . n 
A 1 446 PHE 446 427 427 PHE PHE A . n 
A 1 447 PHE 447 428 428 PHE PHE A . n 
A 1 448 PRO 448 429 429 PRO PRO A . n 
A 1 449 ILE 449 430 430 ILE ILE A . n 
A 1 450 VAL 450 431 431 VAL VAL A . n 
A 1 451 PHE 451 432 432 PHE PHE A . n 
A 1 452 CYS 452 433 433 CYS CYS A . n 
A 1 453 ILE 453 434 434 ILE ILE A . n 
A 1 454 CYS 454 435 435 CYS CYS A . n 
A 1 455 SER 455 436 436 SER SER A . n 
A 1 456 VAL 456 437 437 VAL VAL A . n 
A 1 457 PHE 457 438 438 PHE PHE A . n 
A 1 458 LEU 458 439 439 LEU LEU A . n 
A 1 459 VAL 459 440 440 VAL VAL A . n 
A 1 460 ILE 460 441 441 ILE ILE A . n 
A 1 461 VAL 461 442 442 VAL VAL A . n 
A 1 462 PRO 462 443 443 PRO PRO A . n 
A 1 463 LEU 463 444 444 LEU LEU A . n 
A 1 464 PHE 464 445 445 PHE PHE A . n 
A 1 465 THR 465 446 446 THR THR A . n 
A 1 466 ASP 466 447 447 ASP ASP A . n 
A 1 467 THR 467 448 448 THR THR A . n 
A 1 468 ILE 468 449 449 ILE ILE A . n 
A 1 469 ASN 469 450 450 ASN ASN A . n 
A 1 470 SER 470 451 451 SER SER A . n 
A 1 471 LEU 471 452 452 LEU LEU A . n 
A 1 472 ILE 472 453 453 ILE ILE A . n 
A 1 473 GLY 473 454 454 GLY GLY A . n 
A 1 474 ILE 474 455 455 ILE ILE A . n 
A 1 475 GLY 475 456 456 GLY GLY A . n 
A 1 476 ILE 476 457 457 ILE ILE A . n 
A 1 477 ALA 477 458 458 ALA ALA A . n 
A 1 478 LEU 478 459 459 LEU LEU A . n 
A 1 479 SER 479 460 460 SER SER A . n 
A 1 480 GLY 480 461 461 GLY GLY A . n 
A 1 481 VAL 481 462 462 VAL VAL A . n 
A 1 482 PRO 482 463 463 PRO PRO A . n 
A 1 483 PHE 483 464 464 PHE PHE A . n 
A 1 484 TYR 484 465 465 TYR TYR A . n 
A 1 485 PHE 485 466 466 PHE PHE A . n 
A 1 486 MET 486 467 467 MET MET A . n 
A 1 487 GLY 487 468 468 GLY GLY A . n 
A 1 488 VAL 488 469 469 VAL VAL A . n 
A 1 489 TYR 489 470 470 TYR TYR A . n 
A 1 490 LEU 490 471 471 LEU LEU A . n 
A 1 491 PRO 491 472 472 PRO PRO A . n 
A 1 492 GLU 492 473 473 GLU GLU A . n 
A 1 493 SER 493 474 474 SER SER A . n 
A 1 494 ARG 494 475 475 ARG ARG A . n 
A 1 495 ARG 495 476 476 ARG ARG A . n 
A 1 496 PRO 496 477 477 PRO PRO A . n 
A 1 497 LEU 497 478 478 LEU LEU A . n 
A 1 498 PHE 498 479 479 PHE PHE A . n 
A 1 499 ILE 499 480 480 ILE ILE A . n 
A 1 500 ARG 500 481 481 ARG ARG A . n 
A 1 501 ASN 501 482 482 ASN ASN A . n 
A 1 502 VAL 502 483 483 VAL VAL A . n 
A 1 503 LEU 503 484 484 LEU LEU A . n 
A 1 504 ALA 504 485 485 ALA ALA A . n 
A 1 505 ALA 505 486 486 ALA ALA A . n 
A 1 506 ILE 506 487 487 ILE ILE A . n 
A 1 507 THR 507 488 488 THR THR A . n 
A 1 508 ARG 508 489 489 ARG ARG A . n 
A 1 509 GLY 509 490 490 GLY GLY A . n 
A 1 510 THR 510 491 491 THR THR A . n 
A 1 511 GLN 511 492 492 GLN GLN A . n 
A 1 512 GLN 512 493 493 GLN GLN A . n 
A 1 513 LEU 513 494 494 LEU LEU A . n 
A 1 514 CYS 514 495 495 CYS CYS A . n 
A 1 515 PHE 515 496 496 PHE PHE A . n 
A 1 516 CYS 516 497 497 CYS CYS A . n 
A 1 517 VAL 517 498 498 VAL VAL A . n 
A 1 518 LEU 518 499 499 LEU LEU A . n 
A 1 519 THR 519 500 500 THR THR A . n 
A 1 520 GLU 520 501 501 GLU GLU A . n 
A 1 521 LEU 521 502 ?   ?   ?   A . n 
A 1 522 ASP 522 503 ?   ?   ?   A . n 
A 1 523 VAL 523 504 ?   ?   ?   A . n 
A 1 524 ALA 524 505 ?   ?   ?   A . n 
A 1 525 GLU 525 506 ?   ?   ?   A . n 
A 1 526 GLU 526 507 ?   ?   ?   A . n 
A 1 527 LYS 527 508 ?   ?   ?   A . n 
A 1 528 LYS 528 509 ?   ?   ?   A . n 
A 1 529 ASP 529 510 ?   ?   ?   A . n 
A 1 530 GLU 530 511 ?   ?   ?   A . n 
A 1 531 ARG 531 512 ?   ?   ?   A . n 
A 1 532 LYS 532 513 ?   ?   ?   A . n 
A 1 533 THR 533 514 ?   ?   ?   A . n 
A 1 534 ASP 534 515 ?   ?   ?   A . n 
B 2 1   HIS 1   -10 ?   ?   ?   B . n 
B 2 2   HIS 2   -9  ?   ?   ?   B . n 
B 2 3   HIS 3   -8  ?   ?   ?   B . n 
B 2 4   HIS 4   -7  ?   ?   ?   B . n 
B 2 5   HIS 5   -6  ?   ?   ?   B . n 
B 2 6   HIS 6   -5  ?   ?   ?   B . n 
B 2 7   HIS 7   -4  ?   ?   ?   B . n 
B 2 8   HIS 8   -3  ?   ?   ?   B . n 
B 2 9   HIS 9   -2  ?   ?   ?   B . n 
B 2 10  HIS 10  -1  ?   ?   ?   B . n 
B 2 11  SER 11  0   ?   ?   ?   B . n 
B 2 12  GLY 12  1   ?   ?   ?   B . n 
B 2 13  ARG 13  2   ?   ?   ?   B . n 
B 2 14  GLU 14  3   ?   ?   ?   B . n 
B 2 15  LEU 15  4   ?   ?   ?   B . n 
B 2 16  GLN 16  5   ?   ?   ?   B . n 
B 2 17  PRO 17  6   ?   ?   ?   B . n 
B 2 18  PRO 18  7   ?   ?   ?   B . n 
B 2 19  GLU 19  8   ?   ?   ?   B . n 
B 2 20  ALA 20  9   ?   ?   ?   B . n 
B 2 21  SER 21  10  ?   ?   ?   B . n 
B 2 22  ILE 22  11  ?   ?   ?   B . n 
B 2 23  ALA 23  12  ?   ?   ?   B . n 
B 2 24  VAL 24  13  ?   ?   ?   B . n 
B 2 25  VAL 25  14  ?   ?   ?   B . n 
B 2 26  SER 26  15  ?   ?   ?   B . n 
B 2 27  ILE 27  16  ?   ?   ?   B . n 
B 2 28  PRO 28  17  ?   ?   ?   B . n 
B 2 29  ARG 29  18  ?   ?   ?   B . n 
B 2 30  GLN 30  19  ?   ?   ?   B . n 
B 2 31  LEU 31  20  ?   ?   ?   B . n 
B 2 32  PRO 32  21  ?   ?   ?   B . n 
B 2 33  GLY 33  22  ?   ?   ?   B . n 
B 2 34  SER 34  23  ?   ?   ?   B . n 
B 2 35  HIS 35  24  ?   ?   ?   B . n 
B 2 36  SER 36  25  ?   ?   ?   B . n 
B 2 37  GLU 37  26  ?   ?   ?   B . n 
B 2 38  ALA 38  27  ?   ?   ?   B . n 
B 2 39  GLY 39  28  ?   ?   ?   B . n 
B 2 40  VAL 40  29  ?   ?   ?   B . n 
B 2 41  GLN 41  30  ?   ?   ?   B . n 
B 2 42  GLY 42  31  ?   ?   ?   B . n 
B 2 43  LEU 43  32  ?   ?   ?   B . n 
B 2 44  SER 44  33  ?   ?   ?   B . n 
B 2 45  ALA 45  34  ?   ?   ?   B . n 
B 2 46  GLY 46  35  ?   ?   ?   B . n 
B 2 47  ASP 47  36  ?   ?   ?   B . n 
B 2 48  ASP 48  37  ?   ?   ?   B . n 
B 2 49  SER 49  38  ?   ?   ?   B . n 
B 2 50  GLU 50  39  ?   ?   ?   B . n 
B 2 51  LEU 51  40  ?   ?   ?   B . n 
B 2 52  GLY 52  41  ?   ?   ?   B . n 
B 2 53  SER 53  42  ?   ?   ?   B . n 
B 2 54  HIS 54  43  ?   ?   ?   B . n 
B 2 55  CYS 55  44  ?   ?   ?   B . n 
B 2 56  VAL 56  45  ?   ?   ?   B . n 
B 2 57  ALA 57  46  ?   ?   ?   B . n 
B 2 58  GLN 58  47  ?   ?   ?   B . n 
B 2 59  THR 59  48  ?   ?   ?   B . n 
B 2 60  GLY 60  49  ?   ?   ?   B . n 
B 2 61  LEU 61  50  ?   ?   ?   B . n 
B 2 62  GLU 62  51  ?   ?   ?   B . n 
B 2 63  LEU 63  52  ?   ?   ?   B . n 
B 2 64  LEU 64  53  ?   ?   ?   B . n 
B 2 65  ALA 65  54  ?   ?   ?   B . n 
B 2 66  SER 66  55  ?   ?   ?   B . n 
B 2 67  GLY 67  56  ?   ?   ?   B . n 
B 2 68  ASP 68  57  ?   ?   ?   B . n 
B 2 69  PRO 69  58  ?   ?   ?   B . n 
B 2 70  LEU 70  59  ?   ?   ?   B . n 
B 2 71  PRO 71  60  ?   ?   ?   B . n 
B 2 72  SER 72  61  ?   ?   ?   B . n 
B 2 73  ALA 73  62  ?   ?   ?   B . n 
B 2 74  SER 74  63  ?   ?   ?   B . n 
B 2 75  GLN 75  64  ?   ?   ?   B . n 
B 2 76  ASN 76  65  ?   ?   ?   B . n 
B 2 77  ALA 77  66  ?   ?   ?   B . n 
B 2 78  GLU 78  67  ?   ?   ?   B . n 
B 2 79  MET 79  68  ?   ?   ?   B . n 
B 2 80  ILE 80  69  ?   ?   ?   B . n 
B 2 81  GLU 81  70  ?   ?   ?   B . n 
B 2 82  THR 82  71  ?   ?   ?   B . n 
B 2 83  GLY 83  72  ?   ?   ?   B . n 
B 2 84  SER 84  73  ?   ?   ?   B . n 
B 2 85  ASP 85  74  ?   ?   ?   B . n 
B 2 86  CYS 86  75  ?   ?   ?   B . n 
B 2 87  VAL 87  76  ?   ?   ?   B . n 
B 2 88  THR 88  77  ?   ?   ?   B . n 
B 2 89  GLN 89  78  ?   ?   ?   B . n 
B 2 90  ALA 90  79  ?   ?   ?   B . n 
B 2 91  GLY 91  80  ?   ?   ?   B . n 
B 2 92  LEU 92  81  ?   ?   ?   B . n 
B 2 93  GLN 93  82  ?   ?   ?   B . n 
B 2 94  LEU 94  83  ?   ?   ?   B . n 
B 2 95  LEU 95  84  ?   ?   ?   B . n 
B 2 96  ALA 96  85  ?   ?   ?   B . n 
B 2 97  SER 97  86  ?   ?   ?   B . n 
B 2 98  SER 98  87  ?   ?   ?   B . n 
B 2 99  ASP 99  88  ?   ?   ?   B . n 
B 2 100 PRO 100 89  ?   ?   ?   B . n 
B 2 101 PRO 101 90  ?   ?   ?   B . n 
B 2 102 ALA 102 91  ?   ?   ?   B . n 
B 2 103 LEU 103 92  ?   ?   ?   B . n 
B 2 104 ALA 104 93  ?   ?   ?   B . n 
B 2 105 SER 105 94  ?   ?   ?   B . n 
B 2 106 LYS 106 95  ?   ?   ?   B . n 
B 2 107 ASN 107 96  ?   ?   ?   B . n 
B 2 108 ALA 108 97  ?   ?   ?   B . n 
B 2 109 GLU 109 98  ?   ?   ?   B . n 
B 2 110 VAL 110 99  ?   ?   ?   B . n 
B 2 111 THR 111 100 ?   ?   ?   B . n 
B 2 112 GLY 112 101 ?   ?   ?   B . n 
B 2 113 THR 113 102 ?   ?   ?   B . n 
B 2 114 MET 114 103 ?   ?   ?   B . n 
B 2 115 SER 115 104 ?   ?   ?   B . n 
B 2 116 GLN 116 105 ?   ?   ?   B . n 
B 2 117 ASP 117 106 ?   ?   ?   B . n 
B 2 118 THR 118 107 ?   ?   ?   B . n 
B 2 119 GLU 119 108 ?   ?   ?   B . n 
B 2 120 VAL 120 109 ?   ?   ?   B . n 
B 2 121 ASP 121 110 ?   ?   ?   B . n 
B 2 122 MET 122 111 ?   ?   ?   B . n 
B 2 123 LYS 123 112 ?   ?   ?   B . n 
B 2 124 GLU 124 113 ?   ?   ?   B . n 
B 2 125 VAL 125 114 ?   ?   ?   B . n 
B 2 126 GLU 126 115 ?   ?   ?   B . n 
B 2 127 LEU 127 116 ?   ?   ?   B . n 
B 2 128 ASN 128 117 ?   ?   ?   B . n 
B 2 129 GLU 129 118 ?   ?   ?   B . n 
B 2 130 LEU 130 119 ?   ?   ?   B . n 
B 2 131 GLU 131 120 ?   ?   ?   B . n 
B 2 132 PRO 132 121 ?   ?   ?   B . n 
B 2 133 GLU 133 122 ?   ?   ?   B . n 
B 2 134 LYS 134 123 ?   ?   ?   B . n 
B 2 135 GLN 135 124 ?   ?   ?   B . n 
B 2 136 PRO 136 125 ?   ?   ?   B . n 
B 2 137 MET 137 126 ?   ?   ?   B . n 
B 2 138 ASN 138 127 ?   ?   ?   B . n 
B 2 139 ALA 139 128 ?   ?   ?   B . n 
B 2 140 ALA 140 129 ?   ?   ?   B . n 
B 2 141 SER 141 130 ?   ?   ?   B . n 
B 2 142 GLY 142 131 ?   ?   ?   B . n 
B 2 143 ALA 143 132 ?   ?   ?   B . n 
B 2 144 ALA 144 133 ?   ?   ?   B . n 
B 2 145 MET 145 134 ?   ?   ?   B . n 
B 2 146 SER 146 135 ?   ?   ?   B . n 
B 2 147 LEU 147 136 ?   ?   ?   B . n 
B 2 148 ALA 148 137 ?   ?   ?   B . n 
B 2 149 GLY 149 138 ?   ?   ?   B . n 
B 2 150 ALA 150 139 ?   ?   ?   B . n 
B 2 151 GLU 151 140 ?   ?   ?   B . n 
B 2 152 LYS 152 141 ?   ?   ?   B . n 
B 2 153 ASN 153 142 ?   ?   ?   B . n 
B 2 154 GLY 154 143 ?   ?   ?   B . n 
B 2 155 LEU 155 144 ?   ?   ?   B . n 
B 2 156 VAL 156 145 ?   ?   ?   B . n 
B 2 157 LYS 157 146 ?   ?   ?   B . n 
B 2 158 ILE 158 147 ?   ?   ?   B . n 
B 2 159 LYS 159 148 ?   ?   ?   B . n 
B 2 160 VAL 160 149 ?   ?   ?   B . n 
B 2 161 ALA 161 150 ?   ?   ?   B . n 
B 2 162 GLU 162 151 ?   ?   ?   B . n 
B 2 163 ASP 163 152 ?   ?   ?   B . n 
B 2 164 GLU 164 153 ?   ?   ?   B . n 
B 2 165 ALA 165 154 ?   ?   ?   B . n 
B 2 166 GLU 166 155 ?   ?   ?   B . n 
B 2 167 ALA 167 156 ?   ?   ?   B . n 
B 2 168 ALA 168 157 ?   ?   ?   B . n 
B 2 169 ALA 169 158 ?   ?   ?   B . n 
B 2 170 ALA 170 159 ?   ?   ?   B . n 
B 2 171 ALA 171 160 ?   ?   ?   B . n 
B 2 172 LYS 172 161 161 LYS LYS B . n 
B 2 173 PHE 173 162 162 PHE PHE B . n 
B 2 174 THR 174 163 163 THR THR B . n 
B 2 175 GLY 175 164 164 GLY GLY B . n 
B 2 176 LEU 176 165 165 LEU LEU B . n 
B 2 177 SER 177 166 166 SER SER B . n 
B 2 178 LYS 178 167 167 LYS LYS B . n 
B 2 179 GLU 179 168 168 GLU GLU B . n 
B 2 180 GLU 180 169 169 GLU GLU B . n 
B 2 181 LEU 181 170 170 LEU LEU B . n 
B 2 182 LEU 182 171 171 LEU LEU B . n 
B 2 183 LYS 183 172 172 LYS LYS B . n 
B 2 184 VAL 184 173 173 VAL VAL B . n 
B 2 185 ALA 185 174 174 ALA ALA B . n 
B 2 186 GLY 186 175 175 GLY GLY B . n 
B 2 187 SER 187 176 176 SER SER B . n 
B 2 188 PRO 188 177 177 PRO PRO B . n 
B 2 189 GLY 189 178 178 GLY GLY B . n 
B 2 190 TRP 190 179 179 TRP TRP B . n 
B 2 191 VAL 191 180 180 VAL VAL B . n 
B 2 192 ARG 192 181 181 ARG ARG B . n 
B 2 193 THR 193 182 182 THR THR B . n 
B 2 194 ARG 194 183 183 ARG ARG B . n 
B 2 195 TRP 195 184 184 TRP TRP B . n 
B 2 196 ALA 196 185 185 ALA ALA B . n 
B 2 197 LEU 197 186 186 LEU LEU B . n 
B 2 198 LEU 198 187 187 LEU LEU B . n 
B 2 199 LEU 199 188 188 LEU LEU B . n 
B 2 200 LEU 200 189 189 LEU LEU B . n 
B 2 201 PHE 201 190 190 PHE PHE B . n 
B 2 202 TRP 202 191 191 TRP TRP B . n 
B 2 203 LEU 203 192 192 LEU LEU B . n 
B 2 204 GLY 204 193 193 GLY GLY B . n 
B 2 205 TRP 205 194 194 TRP TRP B . n 
B 2 206 LEU 206 195 195 LEU LEU B . n 
B 2 207 GLY 207 196 196 GLY GLY B . n 
B 2 208 MET 208 197 197 MET MET B . n 
B 2 209 LEU 209 198 198 LEU LEU B . n 
B 2 210 ALA 210 199 199 ALA ALA B . n 
B 2 211 GLY 211 200 200 GLY GLY B . n 
B 2 212 ALA 212 201 201 ALA ALA B . n 
B 2 213 VAL 213 202 202 VAL VAL B . n 
B 2 214 VAL 214 203 203 VAL VAL B . n 
B 2 215 ILE 215 204 204 ILE ILE B . n 
B 2 216 ILE 216 205 205 ILE ILE B . n 
B 2 217 VAL 217 206 206 VAL VAL B . n 
B 2 218 ARG 218 207 207 ARG ARG B . n 
B 2 219 ALA 219 208 208 ALA ALA B . n 
B 2 220 PRO 220 209 209 PRO PRO B . n 
B 2 221 ARG 221 210 210 ARG ARG B . n 
B 2 222 CYS 222 211 211 CYS CYS B . n 
B 2 223 ARG 223 212 212 ARG ARG B . n 
B 2 224 GLU 224 213 213 GLU GLU B . n 
B 2 225 LEU 225 214 214 LEU LEU B . n 
B 2 226 PRO 226 215 215 PRO PRO B . n 
B 2 227 ALA 227 216 216 ALA ALA B . n 
B 2 228 GLN 228 217 217 GLN GLN B . n 
B 2 229 LYS 229 218 218 LYS LYS B . n 
B 2 230 TRP 230 219 219 TRP TRP B . n 
B 2 231 TRP 231 220 220 TRP TRP B . n 
B 2 232 HIS 232 221 221 HIS HIS B . n 
B 2 233 THR 233 222 222 THR THR B . n 
B 2 234 GLY 234 223 223 GLY GLY B . n 
B 2 235 ALA 235 224 224 ALA ALA B . n 
B 2 236 LEU 236 225 225 LEU LEU B . n 
B 2 237 TYR 237 226 226 TYR TYR B . n 
B 2 238 ARG 238 227 227 ARG ARG B . n 
B 2 239 ILE 239 228 228 ILE ILE B . n 
B 2 240 GLY 240 229 229 GLY GLY B . n 
B 2 241 ASP 241 230 230 ASP ASP B . n 
B 2 242 LEU 242 231 231 LEU LEU B . n 
B 2 243 GLN 243 232 232 GLN GLN B . n 
B 2 244 ALA 244 233 233 ALA ALA B . n 
B 2 245 PHE 245 234 234 PHE PHE B . n 
B 2 246 GLN 246 235 235 GLN GLN B . n 
B 2 247 GLY 247 236 236 GLY GLY B . n 
B 2 248 HIS 248 237 237 HIS HIS B . n 
B 2 249 GLY 249 238 238 GLY GLY B . n 
B 2 250 ALA 250 239 239 ALA ALA B . n 
B 2 251 GLY 251 240 240 GLY GLY B . n 
B 2 252 ASN 252 241 241 ASN ASN B . n 
B 2 253 LEU 253 242 242 LEU LEU B . n 
B 2 254 ALA 254 243 243 ALA ALA B . n 
B 2 255 GLY 255 244 244 GLY GLY B . n 
B 2 256 LEU 256 245 245 LEU LEU B . n 
B 2 257 LYS 257 246 246 LYS LYS B . n 
B 2 258 GLY 258 247 247 GLY GLY B . n 
B 2 259 ARG 259 248 248 ARG ARG B . n 
B 2 260 LEU 260 249 249 LEU LEU B . n 
B 2 261 ASP 261 250 250 ASP ASP B . n 
B 2 262 TYR 262 251 251 TYR TYR B . n 
B 2 263 LEU 263 252 252 LEU LEU B . n 
B 2 264 SER 264 253 253 SER SER B . n 
B 2 265 SER 265 254 254 SER SER B . n 
B 2 266 LEU 266 255 255 LEU LEU B . n 
B 2 267 LYS 267 256 256 LYS LYS B . n 
B 2 268 VAL 268 257 257 VAL VAL B . n 
B 2 269 LYS 269 258 258 LYS LYS B . n 
B 2 270 GLY 270 259 259 GLY GLY B . n 
B 2 271 LEU 271 260 260 LEU LEU B . n 
B 2 272 VAL 272 261 261 VAL VAL B . n 
B 2 273 LEU 273 262 262 LEU LEU B . n 
B 2 274 GLY 274 263 263 GLY GLY B . n 
B 2 275 PRO 275 264 264 PRO PRO B . n 
B 2 276 ILE 276 265 265 ILE ILE B . n 
B 2 277 HIS 277 266 266 HIS HIS B . n 
B 2 278 LYS 278 267 267 LYS LYS B . n 
B 2 279 ASN 279 268 268 ASN ASN B . n 
B 2 280 GLN 280 269 269 GLN GLN B . n 
B 2 281 LYS 281 270 270 LYS LYS B . n 
B 2 282 ASP 282 271 271 ASP ASP B . n 
B 2 283 ASP 283 272 272 ASP ASP B . n 
B 2 284 VAL 284 273 273 VAL VAL B . n 
B 2 285 ALA 285 274 274 ALA ALA B . n 
B 2 286 GLN 286 275 275 GLN GLN B . n 
B 2 287 THR 287 276 276 THR THR B . n 
B 2 288 ASP 288 277 277 ASP ASP B . n 
B 2 289 LEU 289 278 278 LEU LEU B . n 
B 2 290 LEU 290 279 279 LEU LEU B . n 
B 2 291 GLN 291 280 280 GLN GLN B . n 
B 2 292 ILE 292 281 281 ILE ILE B . n 
B 2 293 ASP 293 282 282 ASP ASP B . n 
B 2 294 PRO 294 283 283 PRO PRO B . n 
B 2 295 ASN 295 284 284 ASN ASN B . n 
B 2 296 PHE 296 285 285 PHE PHE B . n 
B 2 297 GLY 297 286 286 GLY GLY B . n 
B 2 298 SER 298 287 287 SER SER B . n 
B 2 299 LYS 299 288 288 LYS LYS B . n 
B 2 300 GLU 300 289 289 GLU GLU B . n 
B 2 301 ASP 301 290 290 ASP ASP B . n 
B 2 302 PHE 302 291 291 PHE PHE B . n 
B 2 303 ASP 303 292 292 ASP ASP B . n 
B 2 304 SER 304 293 293 SER SER B . n 
B 2 305 LEU 305 294 294 LEU LEU B . n 
B 2 306 LEU 306 295 295 LEU LEU B . n 
B 2 307 GLN 307 296 296 GLN GLN B . n 
B 2 308 SER 308 297 297 SER SER B . n 
B 2 309 ALA 309 298 298 ALA ALA B . n 
B 2 310 LYS 310 299 299 LYS LYS B . n 
B 2 311 LYS 311 300 300 LYS LYS B . n 
B 2 312 LYS 312 301 301 LYS LYS B . n 
B 2 313 SER 313 302 302 SER SER B . n 
B 2 314 ILE 314 303 303 ILE ILE B . n 
B 2 315 ARG 315 304 304 ARG ARG B . n 
B 2 316 VAL 316 305 305 VAL VAL B . n 
B 2 317 ILE 317 306 306 ILE ILE B . n 
B 2 318 LEU 318 307 307 LEU LEU B . n 
B 2 319 ASP 319 308 308 ASP ASP B . n 
B 2 320 LEU 320 309 309 LEU LEU B . n 
B 2 321 THR 321 310 310 THR THR B . n 
B 2 322 PRO 322 311 311 PRO PRO B . n 
B 2 323 ASN 323 312 312 ASN ASN B . n 
B 2 324 TYR 324 313 313 TYR TYR B . n 
B 2 325 ARG 325 314 314 ARG ARG B . n 
B 2 326 GLY 326 315 315 GLY GLY B . n 
B 2 327 GLU 327 316 316 GLU GLU B . n 
B 2 328 ASN 328 317 317 ASN ASN B . n 
B 2 329 SER 329 318 318 SER SER B . n 
B 2 330 TRP 330 319 319 TRP TRP B . n 
B 2 331 PHE 331 320 320 PHE PHE B . n 
B 2 332 SER 332 321 321 SER SER B . n 
B 2 333 THR 333 322 322 THR THR B . n 
B 2 334 GLN 334 323 323 GLN GLN B . n 
B 2 335 VAL 335 324 324 VAL VAL B . n 
B 2 336 ASP 336 325 325 ASP ASP B . n 
B 2 337 THR 337 326 326 THR THR B . n 
B 2 338 VAL 338 327 327 VAL VAL B . n 
B 2 339 ALA 339 328 328 ALA ALA B . n 
B 2 340 THR 340 329 329 THR THR B . n 
B 2 341 LYS 341 330 330 LYS LYS B . n 
B 2 342 VAL 342 331 331 VAL VAL B . n 
B 2 343 LYS 343 332 332 LYS LYS B . n 
B 2 344 ASP 344 333 333 ASP ASP B . n 
B 2 345 ALA 345 334 334 ALA ALA B . n 
B 2 346 LEU 346 335 335 LEU LEU B . n 
B 2 347 GLU 347 336 336 GLU GLU B . n 
B 2 348 PHE 348 337 337 PHE PHE B . n 
B 2 349 TRP 349 338 338 TRP TRP B . n 
B 2 350 LEU 350 339 339 LEU LEU B . n 
B 2 351 GLN 351 340 340 GLN GLN B . n 
B 2 352 ALA 352 341 341 ALA ALA B . n 
B 2 353 GLY 353 342 342 GLY GLY B . n 
B 2 354 VAL 354 343 343 VAL VAL B . n 
B 2 355 ASP 355 344 344 ASP ASP B . n 
B 2 356 GLY 356 345 345 GLY GLY B . n 
B 2 357 PHE 357 346 346 PHE PHE B . n 
B 2 358 GLN 358 347 347 GLN GLN B . n 
B 2 359 VAL 359 348 348 VAL VAL B . n 
B 2 360 ARG 360 349 349 ARG ARG B . n 
B 2 361 ASP 361 350 350 ASP ASP B . n 
B 2 362 ILE 362 351 351 ILE ILE B . n 
B 2 363 GLU 363 352 352 GLU GLU B . n 
B 2 364 ASN 364 353 353 ASN ASN B . n 
B 2 365 LEU 365 354 354 LEU LEU B . n 
B 2 366 LYS 366 355 355 LYS LYS B . n 
B 2 367 ASP 367 356 356 ASP ASP B . n 
B 2 368 ALA 368 357 357 ALA ALA B . n 
B 2 369 SER 369 358 358 SER SER B . n 
B 2 370 SER 370 359 359 SER SER B . n 
B 2 371 PHE 371 360 360 PHE PHE B . n 
B 2 372 LEU 372 361 361 LEU LEU B . n 
B 2 373 ALA 373 362 362 ALA ALA B . n 
B 2 374 GLU 374 363 363 GLU GLU B . n 
B 2 375 TRP 375 364 364 TRP TRP B . n 
B 2 376 GLN 376 365 365 GLN GLN B . n 
B 2 377 ASN 377 366 366 ASN ASN B . n 
B 2 378 ILE 378 367 367 ILE ILE B . n 
B 2 379 THR 379 368 368 THR THR B . n 
B 2 380 LYS 380 369 369 LYS LYS B . n 
B 2 381 GLY 381 370 370 GLY GLY B . n 
B 2 382 PHE 382 371 371 PHE PHE B . n 
B 2 383 SER 383 372 372 SER SER B . n 
B 2 384 GLU 384 373 373 GLU GLU B . n 
B 2 385 ASP 385 374 374 ASP ASP B . n 
B 2 386 ARG 386 375 375 ARG ARG B . n 
B 2 387 LEU 387 376 376 LEU LEU B . n 
B 2 388 LEU 388 377 377 LEU LEU B . n 
B 2 389 ILE 389 378 378 ILE ILE B . n 
B 2 390 ALA 390 379 379 ALA ALA B . n 
B 2 391 GLY 391 380 380 GLY GLY B . n 
B 2 392 THR 392 381 381 THR THR B . n 
B 2 393 ASN 393 382 382 ASN ASN B . n 
B 2 394 SER 394 383 383 SER SER B . n 
B 2 395 SER 395 384 384 SER SER B . n 
B 2 396 ASP 396 385 385 ASP ASP B . n 
B 2 397 LEU 397 386 386 LEU LEU B . n 
B 2 398 GLN 398 387 387 GLN GLN B . n 
B 2 399 GLN 399 388 388 GLN GLN B . n 
B 2 400 ILE 400 389 389 ILE ILE B . n 
B 2 401 LEU 401 390 390 LEU LEU B . n 
B 2 402 SER 402 391 391 SER SER B . n 
B 2 403 LEU 403 392 392 LEU LEU B . n 
B 2 404 LEU 404 393 393 LEU LEU B . n 
B 2 405 GLU 405 394 394 GLU GLU B . n 
B 2 406 SER 406 395 395 SER SER B . n 
B 2 407 ASN 407 396 396 ASN ASN B . n 
B 2 408 LYS 408 397 397 LYS LYS B . n 
B 2 409 ASP 409 398 398 ASP ASP B . n 
B 2 410 LEU 410 399 399 LEU LEU B . n 
B 2 411 LEU 411 400 400 LEU LEU B . n 
B 2 412 LEU 412 401 401 LEU LEU B . n 
B 2 413 THR 413 402 402 THR THR B . n 
B 2 414 SER 414 403 403 SER SER B . n 
B 2 415 SER 415 404 404 SER SER B . n 
B 2 416 TYR 416 405 405 TYR TYR B . n 
B 2 417 LEU 417 406 406 LEU LEU B . n 
B 2 418 SER 418 407 407 SER SER B . n 
B 2 419 ASP 419 408 408 ASP ASP B . n 
B 2 420 SER 420 409 409 SER SER B . n 
B 2 421 GLY 421 410 410 GLY GLY B . n 
B 2 422 SER 422 411 411 SER SER B . n 
B 2 423 THR 423 412 412 THR THR B . n 
B 2 424 GLY 424 413 413 GLY GLY B . n 
B 2 425 GLU 425 414 414 GLU GLU B . n 
B 2 426 HIS 426 415 415 HIS HIS B . n 
B 2 427 THR 427 416 416 THR THR B . n 
B 2 428 LYS 428 417 417 LYS LYS B . n 
B 2 429 SER 429 418 418 SER SER B . n 
B 2 430 LEU 430 419 419 LEU LEU B . n 
B 2 431 VAL 431 420 420 VAL VAL B . n 
B 2 432 THR 432 421 421 THR THR B . n 
B 2 433 GLN 433 422 422 GLN GLN B . n 
B 2 434 TYR 434 423 423 TYR TYR B . n 
B 2 435 LEU 435 424 424 LEU LEU B . n 
B 2 436 ASN 436 425 425 ASN ASN B . n 
B 2 437 ALA 437 426 426 ALA ALA B . n 
B 2 438 THR 438 427 427 THR THR B . n 
B 2 439 GLY 439 428 428 GLY GLY B . n 
B 2 440 ASN 440 429 429 ASN ASN B . n 
B 2 441 ARG 441 430 430 ARG ARG B . n 
B 2 442 TRP 442 431 431 TRP TRP B . n 
B 2 443 CYS 443 432 432 CYS CYS B . n 
B 2 444 SER 444 433 433 SER SER B . n 
B 2 445 TRP 445 434 434 TRP TRP B . n 
B 2 446 SER 446 435 435 SER SER B . n 
B 2 447 LEU 447 436 436 LEU LEU B . n 
B 2 448 SER 448 437 437 SER SER B . n 
B 2 449 GLN 449 438 438 GLN GLN B . n 
B 2 450 ALA 450 439 439 ALA ALA B . n 
B 2 451 ARG 451 440 440 ARG ARG B . n 
B 2 452 LEU 452 441 441 LEU LEU B . n 
B 2 453 LEU 453 442 442 LEU LEU B . n 
B 2 454 THR 454 443 443 THR THR B . n 
B 2 455 SER 455 444 444 SER SER B . n 
B 2 456 PHE 456 445 445 PHE PHE B . n 
B 2 457 LEU 457 446 446 LEU LEU B . n 
B 2 458 PRO 458 447 447 PRO PRO B . n 
B 2 459 ALA 459 448 448 ALA ALA B . n 
B 2 460 GLN 460 449 449 GLN GLN B . n 
B 2 461 LEU 461 450 450 LEU LEU B . n 
B 2 462 LEU 462 451 451 LEU LEU B . n 
B 2 463 ARG 463 452 452 ARG ARG B . n 
B 2 464 LEU 464 453 453 LEU LEU B . n 
B 2 465 TYR 465 454 454 TYR TYR B . n 
B 2 466 GLN 466 455 455 GLN GLN B . n 
B 2 467 LEU 467 456 456 LEU LEU B . n 
B 2 468 MET 468 457 457 MET MET B . n 
B 2 469 LEU 469 458 458 LEU LEU B . n 
B 2 470 PHE 470 459 459 PHE PHE B . n 
B 2 471 THR 471 460 460 THR THR B . n 
B 2 472 LEU 472 461 461 LEU LEU B . n 
B 2 473 PRO 473 462 462 PRO PRO B . n 
B 2 474 GLY 474 463 463 GLY GLY B . n 
B 2 475 THR 475 464 464 THR THR B . n 
B 2 476 PRO 476 465 465 PRO PRO B . n 
B 2 477 VAL 477 466 466 VAL VAL B . n 
B 2 478 PHE 478 467 467 PHE PHE B . n 
B 2 479 SER 479 468 468 SER SER B . n 
B 2 480 TYR 480 469 469 TYR TYR B . n 
B 2 481 GLY 481 470 470 GLY GLY B . n 
B 2 482 ASP 482 471 471 ASP ASP B . n 
B 2 483 GLU 483 472 472 GLU GLU B . n 
B 2 484 ILE 484 473 473 ILE ILE B . n 
B 2 485 GLY 485 474 474 GLY GLY B . n 
B 2 486 LEU 486 475 475 LEU LEU B . n 
B 2 487 ASP 487 476 476 ASP ASP B . n 
B 2 488 ALA 488 477 477 ALA ALA B . n 
B 2 489 ALA 489 478 478 ALA ALA B . n 
B 2 490 ALA 490 479 479 ALA ALA B . n 
B 2 491 LEU 491 480 480 LEU LEU B . n 
B 2 492 PRO 492 481 481 PRO PRO B . n 
B 2 493 GLY 493 482 482 GLY GLY B . n 
B 2 494 GLN 494 483 483 GLN GLN B . n 
B 2 495 PRO 495 484 484 PRO PRO B . n 
B 2 496 MET 496 485 485 MET MET B . n 
B 2 497 GLU 497 486 486 GLU GLU B . n 
B 2 498 ALA 498 487 487 ALA ALA B . n 
B 2 499 PRO 499 488 488 PRO PRO B . n 
B 2 500 VAL 500 489 489 VAL VAL B . n 
B 2 501 MET 501 490 490 MET MET B . n 
B 2 502 LEU 502 491 491 LEU LEU B . n 
B 2 503 TRP 503 492 492 TRP TRP B . n 
B 2 504 ASP 504 493 493 ASP ASP B . n 
B 2 505 GLU 505 494 494 GLU GLU B . n 
B 2 506 SER 506 495 495 SER SER B . n 
B 2 507 SER 507 496 496 SER SER B . n 
B 2 508 PHE 508 497 497 PHE PHE B . n 
B 2 509 PRO 509 498 498 PRO PRO B . n 
B 2 510 ASP 510 499 499 ASP ASP B . n 
B 2 511 ILE 511 500 500 ILE ILE B . n 
B 2 512 PRO 512 501 501 PRO PRO B . n 
B 2 513 GLY 513 502 502 GLY GLY B . n 
B 2 514 ALA 514 503 503 ALA ALA B . n 
B 2 515 VAL 515 504 504 VAL VAL B . n 
B 2 516 SER 516 505 505 SER SER B . n 
B 2 517 ALA 517 506 506 ALA ALA B . n 
B 2 518 ASN 518 507 507 ASN ASN B . n 
B 2 519 MET 519 508 508 MET MET B . n 
B 2 520 THR 520 509 509 THR THR B . n 
B 2 521 VAL 521 510 510 VAL VAL B . n 
B 2 522 LYS 522 511 511 LYS LYS B . n 
B 2 523 GLY 523 512 512 GLY GLY B . n 
B 2 524 GLN 524 513 513 GLN GLN B . n 
B 2 525 SER 525 514 514 SER SER B . n 
B 2 526 GLU 526 515 515 GLU GLU B . n 
B 2 527 ASP 527 516 516 ASP ASP B . n 
B 2 528 PRO 528 517 517 PRO PRO B . n 
B 2 529 GLY 529 518 518 GLY GLY B . n 
B 2 530 SER 530 519 519 SER SER B . n 
B 2 531 LEU 531 520 520 LEU LEU B . n 
B 2 532 LEU 532 521 521 LEU LEU B . n 
B 2 533 SER 533 522 522 SER SER B . n 
B 2 534 LEU 534 523 523 LEU LEU B . n 
B 2 535 PHE 535 524 524 PHE PHE B . n 
B 2 536 ARG 536 525 525 ARG ARG B . n 
B 2 537 ARG 537 526 526 ARG ARG B . n 
B 2 538 LEU 538 527 527 LEU LEU B . n 
B 2 539 SER 539 528 528 SER SER B . n 
B 2 540 ASP 540 529 529 ASP ASP B . n 
B 2 541 GLN 541 530 530 GLN GLN B . n 
B 2 542 ARG 542 531 531 ARG ARG B . n 
B 2 543 SER 543 532 532 SER SER B . n 
B 2 544 LYS 544 533 533 LYS LYS B . n 
B 2 545 GLU 545 534 534 GLU GLU B . n 
B 2 546 ARG 546 535 535 ARG ARG B . n 
B 2 547 SER 547 536 536 SER SER B . n 
B 2 548 LEU 548 537 537 LEU LEU B . n 
B 2 549 LEU 549 538 538 LEU LEU B . n 
B 2 550 HIS 550 539 539 HIS HIS B . n 
B 2 551 GLY 551 540 540 GLY GLY B . n 
B 2 552 ASP 552 541 541 ASP ASP B . n 
B 2 553 PHE 553 542 542 PHE PHE B . n 
B 2 554 HIS 554 543 543 HIS HIS B . n 
B 2 555 ALA 555 544 544 ALA ALA B . n 
B 2 556 PHE 556 545 545 PHE PHE B . n 
B 2 557 SER 557 546 546 SER SER B . n 
B 2 558 ALA 558 547 547 ALA ALA B . n 
B 2 559 GLY 559 548 548 GLY GLY B . n 
B 2 560 PRO 560 549 549 PRO PRO B . n 
B 2 561 GLY 561 550 550 GLY GLY B . n 
B 2 562 LEU 562 551 551 LEU LEU B . n 
B 2 563 PHE 563 552 552 PHE PHE B . n 
B 2 564 SER 564 553 553 SER SER B . n 
B 2 565 TYR 565 554 554 TYR TYR B . n 
B 2 566 ILE 566 555 555 ILE ILE B . n 
B 2 567 ARG 567 556 556 ARG ARG B . n 
B 2 568 HIS 568 557 557 HIS HIS B . n 
B 2 569 TRP 569 558 558 TRP TRP B . n 
B 2 570 ASP 570 559 559 ASP ASP B . n 
B 2 571 GLN 571 560 560 GLN GLN B . n 
B 2 572 ASN 572 561 561 ASN ASN B . n 
B 2 573 GLU 573 562 562 GLU GLU B . n 
B 2 574 ARG 574 563 563 ARG ARG B . n 
B 2 575 PHE 575 564 564 PHE PHE B . n 
B 2 576 LEU 576 565 565 LEU LEU B . n 
B 2 577 VAL 577 566 566 VAL VAL B . n 
B 2 578 VAL 578 567 567 VAL VAL B . n 
B 2 579 LEU 579 568 568 LEU LEU B . n 
B 2 580 ASN 580 569 569 ASN ASN B . n 
B 2 581 PHE 581 570 570 PHE PHE B . n 
B 2 582 GLY 582 571 571 GLY GLY B . n 
B 2 583 ASP 583 572 572 ASP ASP B . n 
B 2 584 VAL 584 573 573 VAL VAL B . n 
B 2 585 GLY 585 574 574 GLY GLY B . n 
B 2 586 LEU 586 575 575 LEU LEU B . n 
B 2 587 SER 587 576 576 SER SER B . n 
B 2 588 ALA 588 577 577 ALA ALA B . n 
B 2 589 GLY 589 578 578 GLY GLY B . n 
B 2 590 LEU 590 579 579 LEU LEU B . n 
B 2 591 GLN 591 580 580 GLN GLN B . n 
B 2 592 ALA 592 581 581 ALA ALA B . n 
B 2 593 SER 593 582 582 SER SER B . n 
B 2 594 ASP 594 583 583 ASP ASP B . n 
B 2 595 LEU 595 584 584 LEU LEU B . n 
B 2 596 PRO 596 585 585 PRO PRO B . n 
B 2 597 ALA 597 586 586 ALA ALA B . n 
B 2 598 SER 598 587 587 SER SER B . n 
B 2 599 ALA 599 588 588 ALA ALA B . n 
B 2 600 SER 600 589 589 SER SER B . n 
B 2 601 LEU 601 590 590 LEU LEU B . n 
B 2 602 PRO 602 591 591 PRO PRO B . n 
B 2 603 ALA 603 592 592 ALA ALA B . n 
B 2 604 LYS 604 593 593 LYS LYS B . n 
B 2 605 ALA 605 594 594 ALA ALA B . n 
B 2 606 ASP 606 595 595 ASP ASP B . n 
B 2 607 LEU 607 596 596 LEU LEU B . n 
B 2 608 LEU 608 597 597 LEU LEU B . n 
B 2 609 LEU 609 598 598 LEU LEU B . n 
B 2 610 SER 610 599 599 SER SER B . n 
B 2 611 THR 611 600 600 THR THR B . n 
B 2 612 GLN 612 601 601 GLN GLN B . n 
B 2 613 PRO 613 602 602 PRO PRO B . n 
B 2 614 GLY 614 603 603 GLY GLY B . n 
B 2 615 ARG 615 604 604 ARG ARG B . n 
B 2 616 GLU 616 605 605 GLU GLU B . n 
B 2 617 GLU 617 606 606 GLU GLU B . n 
B 2 618 GLY 618 607 607 GLY GLY B . n 
B 2 619 SER 619 608 608 SER SER B . n 
B 2 620 PRO 620 609 609 PRO PRO B . n 
B 2 621 LEU 621 610 610 LEU LEU B . n 
B 2 622 GLU 622 611 611 GLU GLU B . n 
B 2 623 LEU 623 612 612 LEU LEU B . n 
B 2 624 GLU 624 613 613 GLU GLU B . n 
B 2 625 ARG 625 614 614 ARG ARG B . n 
B 2 626 LEU 626 615 615 LEU LEU B . n 
B 2 627 LYS 627 616 616 LYS LYS B . n 
B 2 628 LEU 628 617 617 LEU LEU B . n 
B 2 629 GLU 629 618 618 GLU GLU B . n 
B 2 630 PRO 630 619 619 PRO PRO B . n 
B 2 631 HIS 631 620 620 HIS HIS B . n 
B 2 632 GLU 632 621 621 GLU GLU B . n 
B 2 633 GLY 633 622 622 GLY GLY B . n 
B 2 634 LEU 634 623 623 LEU LEU B . n 
B 2 635 LEU 635 624 624 LEU LEU B . n 
B 2 636 LEU 636 625 625 LEU LEU B . n 
B 2 637 ARG 637 626 626 ARG ARG B . n 
B 2 638 PHE 638 627 627 PHE PHE B . n 
B 2 639 PRO 639 628 628 PRO PRO B . n 
B 2 640 TYR 640 629 629 TYR TYR B . n 
B 2 641 ALA 641 630 630 ALA ALA B . n 
B 2 642 ALA 642 631 631 ALA ALA B . n 
B 2 643 THR 643 632 ?   ?   ?   B . n 
B 2 644 GLY 644 633 ?   ?   ?   B . n 
B 2 645 ALA 645 634 ?   ?   ?   B . n 
# 
_pdbx_nonpoly_scheme.asym_id         C 
_pdbx_nonpoly_scheme.entity_id       3 
_pdbx_nonpoly_scheme.mon_id          ARG 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     601 
_pdbx_nonpoly_scheme.auth_seq_num    601 
_pdbx_nonpoly_scheme.pdb_mon_id      ARG 
_pdbx_nonpoly_scheme.auth_mon_id     ARG 
_pdbx_nonpoly_scheme.pdb_strand_id   A 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9KY5 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9KY5 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9KY5 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9KY5 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            . 
_refine.ls_d_res_low                             ? 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.correlation_coeff_I_to_Fcsqd_work        ? 
_refine.correlation_coeff_I_to_Fcsqd_free        ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'REAL-SPACE (WEIGHTED MAP SUM AT ATOM CENTERS)' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_Zscore 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.004  ? 7458  ? f_bond_d           ? ? ? 
'ELECTRON MICROSCOPY' ? 0.629  ? 10146 ? f_angle_d          ? ? ? 
'ELECTRON MICROSCOPY' ? 15.948 ? 1000  ? f_dihedral_angle_d ? ? ? 
'ELECTRON MICROSCOPY' ? 0.041  ? 1163  ? f_chiral_restr     ? ? ? 
'ELECTRON MICROSCOPY' ? 0.004  ? 1275  ? f_plane_restr      ? ? ? 
# 
_struct.entry_id                     9KY5 
_struct.title                        'Structure of y+LAT2 bound with Arg' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9KY5 
_struct_keywords.text            'complex, membrane protein, amino acid' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP YLAT2_HUMAN Q92536 ? 1 
;MEAREPGRPTPTYHLVPNTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASYGMS
LIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEPTGQAIIAITFANYIIQPSFPSCD
PPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLAL
YSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFSWTI
PIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFF
VGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFI
RNVLAAITRGTQQLCFCVLTELDVAEEKKDERKTD
;
1 
2 UNP 4F2_HUMAN   P08195 ? 2 
;ELQPPEASIAVVSIPRQLPGSHSEAGVQGLSAGDDSELGSHCVAQTGLELLASGDPLPSASQNAEMIETGSDCVTQAGLQ
LLASSDPPALASKNAEVTGTMSQDTEVDMKEVELNELEPEKQPMNAASGAAMSLAGAEKNGLVKIKVAEDEAEAAAAAKF
TGLSKEELLKVAGSPGWVRTRWALLLLFWLGWLGMLAGAVVIIVRAPRCRELPAQKWWHTGALYRIGDLQAFQGHGAGNL
AGLKGRLDYLSSLKVKGLVLGPIHKNQKDDVAQTDLLQIDPNFGSKEDFDSLLQSAKKKSIRVILDLTPNYRGENSWFST
QVDTVATKVKDALEFWLQAGVDGFQVRDIENLKDASSFLAEWQNITKGFSEDRLLIAGTNSSDLQQILSLLESNKDLLLT
SSYLSDSGSTGEHTKSLVTQYLNATGNRWCSWSLSQARLLTSFLPAQLLRLYQLMLFTLPGTPVFSYGDEIGLDAAALPG
QPMEAPVMLWDESSFPDIPGAVSANMTVKGQSEDPGSLLSLFRRLSDQRSKERSLLHGDFHAFSAGPGLFSYIRHWDQNE
RFLVVLNFGDVGLSAGLQASDLPASASLPAKADLLLSTQPGREEGSPLELERLKLEPHEGLLLRFPYAA
;
2 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9KY5 A 20 ? 534 ? Q92536 1 ? 515 ? 1 515 
2 2 9KY5 B 14 ? 642 ? P08195 2 ? 630 ? 3 631 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9KY5 ASP A 1   ? UNP Q92536 ? ? 'expression tag' -18 1  
1 9KY5 TYR A 2   ? UNP Q92536 ? ? 'expression tag' -17 2  
1 9KY5 LYS A 3   ? UNP Q92536 ? ? 'expression tag' -16 3  
1 9KY5 ASP A 4   ? UNP Q92536 ? ? 'expression tag' -15 4  
1 9KY5 ASP A 5   ? UNP Q92536 ? ? 'expression tag' -14 5  
1 9KY5 ASP A 6   ? UNP Q92536 ? ? 'expression tag' -13 6  
1 9KY5 ASP A 7   ? UNP Q92536 ? ? 'expression tag' -12 7  
1 9KY5 LYS A 8   ? UNP Q92536 ? ? 'expression tag' -11 8  
1 9KY5 SER A 9   ? UNP Q92536 ? ? 'expression tag' -10 9  
1 9KY5 GLY A 10  ? UNP Q92536 ? ? 'expression tag' -9  10 
1 9KY5 PRO A 11  ? UNP Q92536 ? ? 'expression tag' -8  11 
1 9KY5 ASP A 12  ? UNP Q92536 ? ? 'expression tag' -7  12 
1 9KY5 GLU A 13  ? UNP Q92536 ? ? 'expression tag' -6  13 
1 9KY5 VAL A 14  ? UNP Q92536 ? ? 'expression tag' -5  14 
1 9KY5 ASP A 15  ? UNP Q92536 ? ? 'expression tag' -4  15 
1 9KY5 ALA A 16  ? UNP Q92536 ? ? 'expression tag' -3  16 
1 9KY5 SER A 17  ? UNP Q92536 ? ? 'expression tag' -2  17 
1 9KY5 GLY A 18  ? UNP Q92536 ? ? 'expression tag' -1  18 
1 9KY5 ARG A 19  ? UNP Q92536 ? ? 'expression tag' 0   19 
2 9KY5 HIS B 1   ? UNP P08195 ? ? 'expression tag' -10 20 
2 9KY5 HIS B 2   ? UNP P08195 ? ? 'expression tag' -9  21 
2 9KY5 HIS B 3   ? UNP P08195 ? ? 'expression tag' -8  22 
2 9KY5 HIS B 4   ? UNP P08195 ? ? 'expression tag' -7  23 
2 9KY5 HIS B 5   ? UNP P08195 ? ? 'expression tag' -6  24 
2 9KY5 HIS B 6   ? UNP P08195 ? ? 'expression tag' -5  25 
2 9KY5 HIS B 7   ? UNP P08195 ? ? 'expression tag' -4  26 
2 9KY5 HIS B 8   ? UNP P08195 ? ? 'expression tag' -3  27 
2 9KY5 HIS B 9   ? UNP P08195 ? ? 'expression tag' -2  28 
2 9KY5 HIS B 10  ? UNP P08195 ? ? 'expression tag' -1  29 
2 9KY5 SER B 11  ? UNP P08195 ? ? 'expression tag' 0   30 
2 9KY5 GLY B 12  ? UNP P08195 ? ? 'expression tag' 1   31 
2 9KY5 ARG B 13  ? UNP P08195 ? ? 'expression tag' 2   32 
2 9KY5 THR B 643 ? UNP P08195 ? ? 'expression tag' 632 33 
2 9KY5 GLY B 644 ? UNP P08195 ? ? 'expression tag' 633 34 
2 9KY5 ALA B 645 ? UNP P08195 ? ? 'expression tag' 634 35 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 65  ? ILE A 78  ? SER A 46  ILE A 59  1 ? 14 
HELX_P HELX_P2  AA2 VAL A 89  ? THR A 93  ? VAL A 70  THR A 74  5 ? 5  
HELX_P HELX_P3  AA3 TYR A 96  ? ILE A 124 ? TYR A 77  ILE A 105 1 ? 29 
HELX_P HELX_P4  AA4 ILE A 134 ? GLY A 139 ? ILE A 115 GLY A 120 1 ? 6  
HELX_P HELX_P5  AA5 GLY A 139 ? VAL A 153 ? GLY A 120 VAL A 134 1 ? 15 
HELX_P HELX_P6  AA6 VAL A 154 ? ILE A 171 ? VAL A 135 ILE A 152 1 ? 18 
HELX_P HELX_P7  AA7 GLN A 172 ? PHE A 175 ? GLN A 153 PHE A 156 5 ? 4  
HELX_P HELX_P8  AA8 PRO A 181 ? TYR A 203 ? PRO A 162 TYR A 184 1 ? 23 
HELX_P HELX_P9  AA9 TYR A 203 ? HIS A 237 ? TYR A 184 HIS A 218 1 ? 35 
HELX_P HELX_P10 AB1 ASP A 251 ? PHE A 264 ? ASP A 232 PHE A 245 1 ? 14 
HELX_P HELX_P11 AB2 ASP A 270 ? PHE A 274 ? ASP A 251 PHE A 255 5 ? 5  
HELX_P HELX_P12 AB3 VAL A 275 ? ILE A 279 ? VAL A 256 ILE A 260 5 ? 5  
HELX_P HELX_P13 AB4 ARG A 284 ? LEU A 312 ? ARG A 265 LEU A 293 1 ? 29 
HELX_P HELX_P14 AB5 ASN A 313 ? SER A 320 ? ASN A 294 SER A 301 1 ? 8  
HELX_P HELX_P15 AB6 ALA A 322 ? PHE A 332 ? ALA A 303 PHE A 313 1 ? 11 
HELX_P HELX_P16 AB7 TRP A 337 ? GLY A 350 ? TRP A 318 GLY A 331 1 ? 14 
HELX_P HELX_P17 AB8 ALA A 357 ? GLY A 369 ? ALA A 338 GLY A 350 1 ? 13 
HELX_P HELX_P18 AB9 PRO A 372 ? MET A 377 ? PRO A 353 MET A 358 5 ? 6  
HELX_P HELX_P19 AC1 PRO A 385 ? TYR A 399 ? PRO A 366 TYR A 380 1 ? 15 
HELX_P HELX_P20 AC2 ASP A 404 ? TYR A 411 ? ASP A 385 TYR A 392 5 ? 8  
HELX_P HELX_P21 AC3 PHE A 414 ? GLU A 434 ? PHE A 395 GLU A 415 1 ? 21 
HELX_P HELX_P22 AC4 VAL A 445 ? THR A 465 ? VAL A 426 THR A 446 1 ? 21 
HELX_P HELX_P23 AC5 ASP A 466 ? SER A 479 ? ASP A 447 SER A 460 1 ? 14 
HELX_P HELX_P24 AC6 GLY A 480 ? VAL A 488 ? GLY A 461 VAL A 469 1 ? 9  
HELX_P HELX_P25 AC7 PRO A 496 ? CYS A 514 ? PRO A 477 CYS A 495 1 ? 19 
HELX_P HELX_P26 AC8 SER B 177 ? VAL B 184 ? SER B 166 VAL B 173 1 ? 8  
HELX_P HELX_P27 AC9 SER B 187 ? VAL B 217 ? SER B 176 VAL B 206 1 ? 31 
HELX_P HELX_P28 AD1 LYS B 229 ? THR B 233 ? LYS B 218 THR B 222 5 ? 5  
HELX_P HELX_P29 AD2 LEU B 242 ? GLY B 247 ? LEU B 231 GLY B 236 1 ? 6  
HELX_P HELX_P30 AD3 ASN B 252 ? LYS B 257 ? ASN B 241 LYS B 246 1 ? 6  
HELX_P HELX_P31 AD4 ARG B 259 ? SER B 264 ? ARG B 248 SER B 253 1 ? 6  
HELX_P HELX_P32 AD5 SER B 298 ? LYS B 312 ? SER B 287 LYS B 301 1 ? 15 
HELX_P HELX_P33 AD6 VAL B 335 ? GLY B 353 ? VAL B 324 GLY B 342 1 ? 19 
HELX_P HELX_P34 AD7 ILE B 362 ? LEU B 365 ? ILE B 351 LEU B 354 5 ? 4  
HELX_P HELX_P35 AD8 ASP B 367 ? SER B 383 ? ASP B 356 SER B 372 1 ? 17 
HELX_P HELX_P36 AD9 ASP B 396 ? LEU B 404 ? ASP B 385 LEU B 393 1 ? 9  
HELX_P HELX_P37 AE1 THR B 423 ? GLY B 439 ? THR B 412 GLY B 428 1 ? 17 
HELX_P HELX_P38 AE2 PRO B 458 ? GLN B 460 ? PRO B 447 GLN B 449 5 ? 3  
HELX_P HELX_P39 AE3 LEU B 461 ? PHE B 470 ? LEU B 450 PHE B 459 1 ? 10 
HELX_P HELX_P40 AE4 THR B 520 ? GLU B 526 ? THR B 509 GLU B 515 1 ? 7  
HELX_P HELX_P41 AE5 LEU B 531 ? SER B 543 ? LEU B 520 SER B 532 1 ? 13 
HELX_P HELX_P42 AE6 GLU B 545 ? HIS B 550 ? GLU B 534 HIS B 539 1 ? 6  
HELX_P HELX_P43 AE7 PRO B 596 ? SER B 600 ? PRO B 585 SER B 589 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_conn.id                            disulf1 
_struct_conn.conn_type_id                  disulf 
_struct_conn.pdbx_leaving_atom_flag        ? 
_struct_conn.pdbx_PDB_id                   ? 
_struct_conn.ptnr1_label_asym_id           A 
_struct_conn.ptnr1_label_comp_id           CYS 
_struct_conn.ptnr1_label_seq_id            178 
_struct_conn.ptnr1_label_atom_id           SG 
_struct_conn.pdbx_ptnr1_label_alt_id       ? 
_struct_conn.pdbx_ptnr1_PDB_ins_code       ? 
_struct_conn.pdbx_ptnr1_standard_comp_id   ? 
_struct_conn.ptnr1_symmetry                1_555 
_struct_conn.ptnr2_label_asym_id           B 
_struct_conn.ptnr2_label_comp_id           CYS 
_struct_conn.ptnr2_label_seq_id            222 
_struct_conn.ptnr2_label_atom_id           SG 
_struct_conn.pdbx_ptnr2_label_alt_id       ? 
_struct_conn.pdbx_ptnr2_PDB_ins_code       ? 
_struct_conn.ptnr1_auth_asym_id            A 
_struct_conn.ptnr1_auth_comp_id            CYS 
_struct_conn.ptnr1_auth_seq_id             159 
_struct_conn.ptnr2_auth_asym_id            B 
_struct_conn.ptnr2_auth_comp_id            CYS 
_struct_conn.ptnr2_auth_seq_id             211 
_struct_conn.ptnr2_symmetry                1_555 
_struct_conn.pdbx_ptnr3_label_atom_id      ? 
_struct_conn.pdbx_ptnr3_label_seq_id       ? 
_struct_conn.pdbx_ptnr3_label_comp_id      ? 
_struct_conn.pdbx_ptnr3_label_asym_id      ? 
_struct_conn.pdbx_ptnr3_label_alt_id       ? 
_struct_conn.pdbx_ptnr3_PDB_ins_code       ? 
_struct_conn.details                       ? 
_struct_conn.pdbx_dist_value               2.030 
_struct_conn.pdbx_value_order              ? 
_struct_conn.pdbx_role                     ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_pdbx_modification_feature.ordinal                            1 
_pdbx_modification_feature.label_comp_id                      CYS 
_pdbx_modification_feature.label_asym_id                      A 
_pdbx_modification_feature.label_seq_id                       178 
_pdbx_modification_feature.label_alt_id                       ? 
_pdbx_modification_feature.modified_residue_label_comp_id     CYS 
_pdbx_modification_feature.modified_residue_label_asym_id     B 
_pdbx_modification_feature.modified_residue_label_seq_id      222 
_pdbx_modification_feature.modified_residue_label_alt_id      ? 
_pdbx_modification_feature.auth_comp_id                       CYS 
_pdbx_modification_feature.auth_asym_id                       A 
_pdbx_modification_feature.auth_seq_id                        159 
_pdbx_modification_feature.PDB_ins_code                       ? 
_pdbx_modification_feature.symmetry                           1_555 
_pdbx_modification_feature.modified_residue_auth_comp_id      CYS 
_pdbx_modification_feature.modified_residue_auth_asym_id      B 
_pdbx_modification_feature.modified_residue_auth_seq_id       211 
_pdbx_modification_feature.modified_residue_PDB_ins_code      ? 
_pdbx_modification_feature.modified_residue_symmetry          1_555 
_pdbx_modification_feature.comp_id_linking_atom               SG 
_pdbx_modification_feature.modified_residue_id_linking_atom   SG 
_pdbx_modification_feature.modified_residue_id                . 
_pdbx_modification_feature.ref_pcm_id                         . 
_pdbx_modification_feature.ref_comp_id                        . 
_pdbx_modification_feature.type                               None 
_pdbx_modification_feature.category                           'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 3 ? 
AA3 ? 2 ? 
AA4 ? 3 ? 
AA5 ? 4 ? 
AA6 ? 2 ? 
AA7 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? parallel      
AA3 1 2 ? parallel      
AA4 1 2 ? parallel      
AA4 2 3 ? parallel      
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA7 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE A 378 ? HIS A 379 ? ILE A 359 HIS A 360 
AA1 2 CYS A 516 ? VAL A 517 ? CYS A 497 VAL A 498 
AA2 1 LEU B 236 ? TYR B 237 ? LEU B 225 TYR B 226 
AA2 2 GLY B 474 ? PHE B 478 ? GLY B 463 PHE B 467 
AA2 3 CYS B 443 ? TRP B 445 ? CYS B 432 TRP B 434 
AA3 1 VAL B 272 ? LEU B 273 ? VAL B 261 LEU B 262 
AA3 2 ILE B 317 ? LEU B 318 ? ILE B 306 LEU B 307 
AA4 1 PHE B 357 ? ARG B 360 ? PHE B 346 ARG B 349 
AA4 2 LEU B 388 ? THR B 392 ? LEU B 377 THR B 381 
AA4 3 LEU B 411 ? SER B 414 ? LEU B 400 SER B 403 
AA5 1 ASP B 552 ? ALA B 555 ? ASP B 541 ALA B 544 
AA5 2 LEU B 562 ? HIS B 568 ? LEU B 551 HIS B 557 
AA5 3 ARG B 574 ? ASN B 580 ? ARG B 563 ASN B 569 
AA5 4 GLY B 633 ? PHE B 638 ? GLY B 622 PHE B 627 
AA6 1 LEU B 586 ? SER B 587 ? LEU B 575 SER B 576 
AA6 2 LYS B 627 ? LEU B 628 ? LYS B 616 LEU B 617 
AA7 1 LYS B 604 ? ALA B 605 ? LYS B 593 ALA B 594 
AA7 2 LEU B 621 ? GLU B 622 ? LEU B 610 GLU B 611 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ILE A 378 ? N ILE A 359 O VAL A 517 ? O VAL A 498 
AA2 1 2 N LEU B 236 ? N LEU B 225 O PRO B 476 ? O PRO B 465 
AA2 2 3 O THR B 475 ? O THR B 464 N CYS B 443 ? N CYS B 432 
AA3 1 2 N LEU B 273 ? N LEU B 262 O ILE B 317 ? O ILE B 306 
AA4 1 2 N VAL B 359 ? N VAL B 348 O ILE B 389 ? O ILE B 378 
AA4 2 3 N THR B 392 ? N THR B 381 O THR B 413 ? O THR B 402 
AA5 1 2 N HIS B 554 ? N HIS B 543 O ILE B 566 ? O ILE B 555 
AA5 2 3 N ARG B 567 ? N ARG B 556 O PHE B 575 ? O PHE B 564 
AA5 3 4 N LEU B 576 ? N LEU B 565 O LEU B 636 ? O LEU B 625 
AA6 1 2 N LEU B 586 ? N LEU B 575 O LEU B 628 ? O LEU B 617 
AA7 1 2 N ALA B 605 ? N ALA B 594 O LEU B 621 ? O LEU B 610 
# 
_pdbx_entry_details.entry_id                   9KY5 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 LYS A 42  ? ? 58.91   71.95   
2  1 GLU A 44  ? ? -142.42 44.60   
3  1 SER A 66  ? ? -157.56 72.29   
4  1 PRO A 67  ? ? -86.30  44.96   
5  1 ALA A 110 ? ? 64.26   -7.83   
6  1 ALA A 118 ? ? 75.51   -7.34   
7  1 LEU A 133 ? ? -94.04  -60.85  
8  1 SER A 219 ? ? 37.19   54.44   
9  1 PHE A 222 ? ? -94.07  54.50   
10 1 PHE A 226 ? ? 74.87   -4.87   
11 1 LEU B 260 ? ? -173.20 149.01  
12 1 LYS B 270 ? ? -167.54 -165.47 
13 1 LYS B 301 ? ? -93.30  50.20   
14 1 SER B 302 ? ? 37.28   41.52   
15 1 GLU B 394 ? ? -91.80  -60.11  
16 1 ILE B 500 ? ? 36.14   56.00   
17 1 TRP B 558 ? ? -96.18  -74.00  
18 1 ASP B 559 ? ? -129.55 -63.18  
19 1 PHE B 570 ? ? -92.07  53.09   
20 1 SER B 582 ? ? 55.44   9.07    
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9KY5 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9KY5 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.60 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               175906 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Structure of the y+LAT2 bound with Arg' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2' 
# 
_em_imaging.entry_id                        9KY5 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               OTHER 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1200 
_em_imaging.nominal_defocus_max             5000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
_em_imaging.objective_aperture              ? 
_em_imaging.microscope_serial_number        ? 
_em_imaging.microscope_version              ? 
# 
_em_vitrification.entry_id              9KY5 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9KY5 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A ASP -18 ? A ASP 1   
2   1 Y 1 A TYR -17 ? A TYR 2   
3   1 Y 1 A LYS -16 ? A LYS 3   
4   1 Y 1 A ASP -15 ? A ASP 4   
5   1 Y 1 A ASP -14 ? A ASP 5   
6   1 Y 1 A ASP -13 ? A ASP 6   
7   1 Y 1 A ASP -12 ? A ASP 7   
8   1 Y 1 A LYS -11 ? A LYS 8   
9   1 Y 1 A SER -10 ? A SER 9   
10  1 Y 1 A GLY -9  ? A GLY 10  
11  1 Y 1 A PRO -8  ? A PRO 11  
12  1 Y 1 A ASP -7  ? A ASP 12  
13  1 Y 1 A GLU -6  ? A GLU 13  
14  1 Y 1 A VAL -5  ? A VAL 14  
15  1 Y 1 A ASP -4  ? A ASP 15  
16  1 Y 1 A ALA -3  ? A ALA 16  
17  1 Y 1 A SER -2  ? A SER 17  
18  1 Y 1 A GLY -1  ? A GLY 18  
19  1 Y 1 A ARG 0   ? A ARG 19  
20  1 Y 1 A MET 1   ? A MET 20  
21  1 Y 1 A GLU 2   ? A GLU 21  
22  1 Y 1 A ALA 3   ? A ALA 22  
23  1 Y 1 A ARG 4   ? A ARG 23  
24  1 Y 1 A GLU 5   ? A GLU 24  
25  1 Y 1 A PRO 6   ? A PRO 25  
26  1 Y 1 A GLY 7   ? A GLY 26  
27  1 Y 1 A ARG 8   ? A ARG 27  
28  1 Y 1 A PRO 9   ? A PRO 28  
29  1 Y 1 A THR 10  ? A THR 29  
30  1 Y 1 A PRO 11  ? A PRO 30  
31  1 Y 1 A THR 12  ? A THR 31  
32  1 Y 1 A TYR 13  ? A TYR 32  
33  1 Y 1 A HIS 14  ? A HIS 33  
34  1 Y 1 A LEU 15  ? A LEU 34  
35  1 Y 1 A VAL 16  ? A VAL 35  
36  1 Y 1 A PRO 17  ? A PRO 36  
37  1 Y 1 A ASN 18  ? A ASN 37  
38  1 Y 1 A THR 19  ? A THR 38  
39  1 Y 1 A SER 20  ? A SER 39  
40  1 Y 1 A GLN 21  ? A GLN 40  
41  1 Y 1 A SER 22  ? A SER 41  
42  1 Y 1 A GLN 23  ? A GLN 42  
43  1 Y 1 A VAL 24  ? A VAL 43  
44  1 Y 1 A GLU 25  ? A GLU 44  
45  1 Y 1 A GLU 26  ? A GLU 45  
46  1 Y 1 A ASP 27  ? A ASP 46  
47  1 Y 1 A VAL 28  ? A VAL 47  
48  1 Y 1 A SER 29  ? A SER 48  
49  1 Y 1 A SER 30  ? A SER 49  
50  1 Y 1 A PRO 31  ? A PRO 50  
51  1 Y 1 A PRO 32  ? A PRO 51  
52  1 Y 1 A GLN 33  ? A GLN 52  
53  1 Y 1 A ARG 34  ? A ARG 53  
54  1 Y 1 A SER 35  ? A SER 54  
55  1 Y 1 A SER 36  ? A SER 55  
56  1 Y 1 A GLU 37  ? A GLU 56  
57  1 Y 1 A THR 38  ? A THR 57  
58  1 Y 1 A LEU 502 ? A LEU 521 
59  1 Y 1 A ASP 503 ? A ASP 522 
60  1 Y 1 A VAL 504 ? A VAL 523 
61  1 Y 1 A ALA 505 ? A ALA 524 
62  1 Y 1 A GLU 506 ? A GLU 525 
63  1 Y 1 A GLU 507 ? A GLU 526 
64  1 Y 1 A LYS 508 ? A LYS 527 
65  1 Y 1 A LYS 509 ? A LYS 528 
66  1 Y 1 A ASP 510 ? A ASP 529 
67  1 Y 1 A GLU 511 ? A GLU 530 
68  1 Y 1 A ARG 512 ? A ARG 531 
69  1 Y 1 A LYS 513 ? A LYS 532 
70  1 Y 1 A THR 514 ? A THR 533 
71  1 Y 1 A ASP 515 ? A ASP 534 
72  1 Y 1 B HIS -10 ? B HIS 1   
73  1 Y 1 B HIS -9  ? B HIS 2   
74  1 Y 1 B HIS -8  ? B HIS 3   
75  1 Y 1 B HIS -7  ? B HIS 4   
76  1 Y 1 B HIS -6  ? B HIS 5   
77  1 Y 1 B HIS -5  ? B HIS 6   
78  1 Y 1 B HIS -4  ? B HIS 7   
79  1 Y 1 B HIS -3  ? B HIS 8   
80  1 Y 1 B HIS -2  ? B HIS 9   
81  1 Y 1 B HIS -1  ? B HIS 10  
82  1 Y 1 B SER 0   ? B SER 11  
83  1 Y 1 B GLY 1   ? B GLY 12  
84  1 Y 1 B ARG 2   ? B ARG 13  
85  1 Y 1 B GLU 3   ? B GLU 14  
86  1 Y 1 B LEU 4   ? B LEU 15  
87  1 Y 1 B GLN 5   ? B GLN 16  
88  1 Y 1 B PRO 6   ? B PRO 17  
89  1 Y 1 B PRO 7   ? B PRO 18  
90  1 Y 1 B GLU 8   ? B GLU 19  
91  1 Y 1 B ALA 9   ? B ALA 20  
92  1 Y 1 B SER 10  ? B SER 21  
93  1 Y 1 B ILE 11  ? B ILE 22  
94  1 Y 1 B ALA 12  ? B ALA 23  
95  1 Y 1 B VAL 13  ? B VAL 24  
96  1 Y 1 B VAL 14  ? B VAL 25  
97  1 Y 1 B SER 15  ? B SER 26  
98  1 Y 1 B ILE 16  ? B ILE 27  
99  1 Y 1 B PRO 17  ? B PRO 28  
100 1 Y 1 B ARG 18  ? B ARG 29  
101 1 Y 1 B GLN 19  ? B GLN 30  
102 1 Y 1 B LEU 20  ? B LEU 31  
103 1 Y 1 B PRO 21  ? B PRO 32  
104 1 Y 1 B GLY 22  ? B GLY 33  
105 1 Y 1 B SER 23  ? B SER 34  
106 1 Y 1 B HIS 24  ? B HIS 35  
107 1 Y 1 B SER 25  ? B SER 36  
108 1 Y 1 B GLU 26  ? B GLU 37  
109 1 Y 1 B ALA 27  ? B ALA 38  
110 1 Y 1 B GLY 28  ? B GLY 39  
111 1 Y 1 B VAL 29  ? B VAL 40  
112 1 Y 1 B GLN 30  ? B GLN 41  
113 1 Y 1 B GLY 31  ? B GLY 42  
114 1 Y 1 B LEU 32  ? B LEU 43  
115 1 Y 1 B SER 33  ? B SER 44  
116 1 Y 1 B ALA 34  ? B ALA 45  
117 1 Y 1 B GLY 35  ? B GLY 46  
118 1 Y 1 B ASP 36  ? B ASP 47  
119 1 Y 1 B ASP 37  ? B ASP 48  
120 1 Y 1 B SER 38  ? B SER 49  
121 1 Y 1 B GLU 39  ? B GLU 50  
122 1 Y 1 B LEU 40  ? B LEU 51  
123 1 Y 1 B GLY 41  ? B GLY 52  
124 1 Y 1 B SER 42  ? B SER 53  
125 1 Y 1 B HIS 43  ? B HIS 54  
126 1 Y 1 B CYS 44  ? B CYS 55  
127 1 Y 1 B VAL 45  ? B VAL 56  
128 1 Y 1 B ALA 46  ? B ALA 57  
129 1 Y 1 B GLN 47  ? B GLN 58  
130 1 Y 1 B THR 48  ? B THR 59  
131 1 Y 1 B GLY 49  ? B GLY 60  
132 1 Y 1 B LEU 50  ? B LEU 61  
133 1 Y 1 B GLU 51  ? B GLU 62  
134 1 Y 1 B LEU 52  ? B LEU 63  
135 1 Y 1 B LEU 53  ? B LEU 64  
136 1 Y 1 B ALA 54  ? B ALA 65  
137 1 Y 1 B SER 55  ? B SER 66  
138 1 Y 1 B GLY 56  ? B GLY 67  
139 1 Y 1 B ASP 57  ? B ASP 68  
140 1 Y 1 B PRO 58  ? B PRO 69  
141 1 Y 1 B LEU 59  ? B LEU 70  
142 1 Y 1 B PRO 60  ? B PRO 71  
143 1 Y 1 B SER 61  ? B SER 72  
144 1 Y 1 B ALA 62  ? B ALA 73  
145 1 Y 1 B SER 63  ? B SER 74  
146 1 Y 1 B GLN 64  ? B GLN 75  
147 1 Y 1 B ASN 65  ? B ASN 76  
148 1 Y 1 B ALA 66  ? B ALA 77  
149 1 Y 1 B GLU 67  ? B GLU 78  
150 1 Y 1 B MET 68  ? B MET 79  
151 1 Y 1 B ILE 69  ? B ILE 80  
152 1 Y 1 B GLU 70  ? B GLU 81  
153 1 Y 1 B THR 71  ? B THR 82  
154 1 Y 1 B GLY 72  ? B GLY 83  
155 1 Y 1 B SER 73  ? B SER 84  
156 1 Y 1 B ASP 74  ? B ASP 85  
157 1 Y 1 B CYS 75  ? B CYS 86  
158 1 Y 1 B VAL 76  ? B VAL 87  
159 1 Y 1 B THR 77  ? B THR 88  
160 1 Y 1 B GLN 78  ? B GLN 89  
161 1 Y 1 B ALA 79  ? B ALA 90  
162 1 Y 1 B GLY 80  ? B GLY 91  
163 1 Y 1 B LEU 81  ? B LEU 92  
164 1 Y 1 B GLN 82  ? B GLN 93  
165 1 Y 1 B LEU 83  ? B LEU 94  
166 1 Y 1 B LEU 84  ? B LEU 95  
167 1 Y 1 B ALA 85  ? B ALA 96  
168 1 Y 1 B SER 86  ? B SER 97  
169 1 Y 1 B SER 87  ? B SER 98  
170 1 Y 1 B ASP 88  ? B ASP 99  
171 1 Y 1 B PRO 89  ? B PRO 100 
172 1 Y 1 B PRO 90  ? B PRO 101 
173 1 Y 1 B ALA 91  ? B ALA 102 
174 1 Y 1 B LEU 92  ? B LEU 103 
175 1 Y 1 B ALA 93  ? B ALA 104 
176 1 Y 1 B SER 94  ? B SER 105 
177 1 Y 1 B LYS 95  ? B LYS 106 
178 1 Y 1 B ASN 96  ? B ASN 107 
179 1 Y 1 B ALA 97  ? B ALA 108 
180 1 Y 1 B GLU 98  ? B GLU 109 
181 1 Y 1 B VAL 99  ? B VAL 110 
182 1 Y 1 B THR 100 ? B THR 111 
183 1 Y 1 B GLY 101 ? B GLY 112 
184 1 Y 1 B THR 102 ? B THR 113 
185 1 Y 1 B MET 103 ? B MET 114 
186 1 Y 1 B SER 104 ? B SER 115 
187 1 Y 1 B GLN 105 ? B GLN 116 
188 1 Y 1 B ASP 106 ? B ASP 117 
189 1 Y 1 B THR 107 ? B THR 118 
190 1 Y 1 B GLU 108 ? B GLU 119 
191 1 Y 1 B VAL 109 ? B VAL 120 
192 1 Y 1 B ASP 110 ? B ASP 121 
193 1 Y 1 B MET 111 ? B MET 122 
194 1 Y 1 B LYS 112 ? B LYS 123 
195 1 Y 1 B GLU 113 ? B GLU 124 
196 1 Y 1 B VAL 114 ? B VAL 125 
197 1 Y 1 B GLU 115 ? B GLU 126 
198 1 Y 1 B LEU 116 ? B LEU 127 
199 1 Y 1 B ASN 117 ? B ASN 128 
200 1 Y 1 B GLU 118 ? B GLU 129 
201 1 Y 1 B LEU 119 ? B LEU 130 
202 1 Y 1 B GLU 120 ? B GLU 131 
203 1 Y 1 B PRO 121 ? B PRO 132 
204 1 Y 1 B GLU 122 ? B GLU 133 
205 1 Y 1 B LYS 123 ? B LYS 134 
206 1 Y 1 B GLN 124 ? B GLN 135 
207 1 Y 1 B PRO 125 ? B PRO 136 
208 1 Y 1 B MET 126 ? B MET 137 
209 1 Y 1 B ASN 127 ? B ASN 138 
210 1 Y 1 B ALA 128 ? B ALA 139 
211 1 Y 1 B ALA 129 ? B ALA 140 
212 1 Y 1 B SER 130 ? B SER 141 
213 1 Y 1 B GLY 131 ? B GLY 142 
214 1 Y 1 B ALA 132 ? B ALA 143 
215 1 Y 1 B ALA 133 ? B ALA 144 
216 1 Y 1 B MET 134 ? B MET 145 
217 1 Y 1 B SER 135 ? B SER 146 
218 1 Y 1 B LEU 136 ? B LEU 147 
219 1 Y 1 B ALA 137 ? B ALA 148 
220 1 Y 1 B GLY 138 ? B GLY 149 
221 1 Y 1 B ALA 139 ? B ALA 150 
222 1 Y 1 B GLU 140 ? B GLU 151 
223 1 Y 1 B LYS 141 ? B LYS 152 
224 1 Y 1 B ASN 142 ? B ASN 153 
225 1 Y 1 B GLY 143 ? B GLY 154 
226 1 Y 1 B LEU 144 ? B LEU 155 
227 1 Y 1 B VAL 145 ? B VAL 156 
228 1 Y 1 B LYS 146 ? B LYS 157 
229 1 Y 1 B ILE 147 ? B ILE 158 
230 1 Y 1 B LYS 148 ? B LYS 159 
231 1 Y 1 B VAL 149 ? B VAL 160 
232 1 Y 1 B ALA 150 ? B ALA 161 
233 1 Y 1 B GLU 151 ? B GLU 162 
234 1 Y 1 B ASP 152 ? B ASP 163 
235 1 Y 1 B GLU 153 ? B GLU 164 
236 1 Y 1 B ALA 154 ? B ALA 165 
237 1 Y 1 B GLU 155 ? B GLU 166 
238 1 Y 1 B ALA 156 ? B ALA 167 
239 1 Y 1 B ALA 157 ? B ALA 168 
240 1 Y 1 B ALA 158 ? B ALA 169 
241 1 Y 1 B ALA 159 ? B ALA 170 
242 1 Y 1 B ALA 160 ? B ALA 171 
243 1 Y 1 B THR 632 ? B THR 643 
244 1 Y 1 B GLY 633 ? B GLY 644 
245 1 Y 1 B ALA 634 ? B ALA 645 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-12-08 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           9KY5 
_em_admin.last_update        2025-04-23 
_em_admin.map_release_date   2025-04-23 
_em_admin.title              'Structure of y+LAT2 bound with Arg' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
_em_software.reference_DOI 
'PARTICLE SELECTION'            ? 1  1 ? ? ? ? ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ? ? ? 
MASKING                         ? 3  ? ? ? ? ? ? 
'CTF CORRECTION'                ? 4  1 ? ? ? ? ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ? ? ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ? ? ? 
'MODEL FITTING'                 ? 7  ? ? ? ? ? ? 
'MODEL REFINEMENT'              ? 8  ? ? ? ? ? ? 
OTHER                           ? 9  ? ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ? ? ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ? ? ? 
CLASSIFICATION                  ? 12 1 ? ? ? ? ? 
RECONSTRUCTION                  ? 13 1 ? ? ? ? ? 
'VOLUME SELECTION'              ? 14 1 1 1 ? ? ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ? ? ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ? ? ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ? ? ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ? ? ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ? ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9KY5 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . MET A 1 58  ? 140.453 116.586 117.508 1.00 88.53  ? 39  MET A N   1 
ATOM   2    C CA  . MET A 1 58  ? 139.053 116.275 117.760 1.00 88.53  ? 39  MET A CA  1 
ATOM   3    C C   . MET A 1 58  ? 138.280 115.993 116.479 1.00 88.53  ? 39  MET A C   1 
ATOM   4    O O   . MET A 1 58  ? 137.115 116.363 116.361 1.00 88.53  ? 39  MET A O   1 
ATOM   5    C CB  . MET A 1 58  ? 138.389 117.416 118.529 1.00 88.53  ? 39  MET A CB  1 
ATOM   6    C CG  . MET A 1 58  ? 138.649 117.360 120.017 1.00 88.53  ? 39  MET A CG  1 
ATOM   7    S SD  . MET A 1 58  ? 140.369 117.713 120.406 1.00 88.53  ? 39  MET A SD  1 
ATOM   8    C CE  . MET A 1 58  ? 140.430 119.466 120.093 1.00 88.53  ? 39  MET A CE  1 
ATOM   9    N N   . GLN A 1 59  ? 138.932 115.341 115.519 1.00 77.60  ? 40  GLN A N   1 
ATOM   10   C CA  . GLN A 1 59  ? 138.243 114.889 114.322 1.00 77.60  ? 40  GLN A CA  1 
ATOM   11   C C   . GLN A 1 59  ? 137.244 113.795 114.688 1.00 77.60  ? 40  GLN A C   1 
ATOM   12   O O   . GLN A 1 59  ? 137.273 113.234 115.785 1.00 77.60  ? 40  GLN A O   1 
ATOM   13   C CB  . GLN A 1 59  ? 139.238 114.395 113.274 1.00 77.60  ? 40  GLN A CB  1 
ATOM   14   C CG  . GLN A 1 59  ? 139.942 113.107 113.641 1.00 77.60  ? 40  GLN A CG  1 
ATOM   15   C CD  . GLN A 1 59  ? 140.793 112.570 112.512 1.00 77.60  ? 40  GLN A CD  1 
ATOM   16   O OE1 . GLN A 1 59  ? 140.896 113.182 111.450 1.00 77.60  ? 40  GLN A OE1 1 
ATOM   17   N NE2 . GLN A 1 59  ? 141.407 111.416 112.734 1.00 77.60  ? 40  GLN A NE2 1 
ATOM   18   N N   . LEU A 1 60  ? 136.357 113.479 113.747 1.00 60.08  ? 41  LEU A N   1 
ATOM   19   C CA  . LEU A 1 60  ? 135.180 112.685 114.081 1.00 60.08  ? 41  LEU A CA  1 
ATOM   20   C C   . LEU A 1 60  ? 135.491 111.222 114.400 1.00 60.08  ? 41  LEU A C   1 
ATOM   21   O O   . LEU A 1 60  ? 134.548 110.459 114.635 1.00 60.08  ? 41  LEU A O   1 
ATOM   22   C CB  . LEU A 1 60  ? 134.161 112.778 112.946 1.00 60.08  ? 41  LEU A CB  1 
ATOM   23   C CG  . LEU A 1 60  ? 132.695 112.659 113.362 1.00 60.08  ? 41  LEU A CG  1 
ATOM   24   C CD1 . LEU A 1 60  ? 132.449 113.390 114.664 1.00 60.08  ? 41  LEU A CD1 1 
ATOM   25   C CD2 . LEU A 1 60  ? 131.804 113.214 112.276 1.00 60.08  ? 41  LEU A CD2 1 
ATOM   26   N N   . LYS A 1 61  ? 136.761 110.813 114.436 1.00 67.18  ? 42  LYS A N   1 
ATOM   27   C CA  . LYS A 1 61  ? 137.160 109.553 115.066 1.00 67.18  ? 42  LYS A CA  1 
ATOM   28   C C   . LYS A 1 61  ? 136.453 108.356 114.421 1.00 67.18  ? 42  LYS A C   1 
ATOM   29   O O   . LYS A 1 61  ? 135.518 107.777 114.975 1.00 67.18  ? 42  LYS A O   1 
ATOM   30   C CB  . LYS A 1 61  ? 136.901 109.606 116.577 1.00 67.18  ? 42  LYS A CB  1 
ATOM   31   C CG  . LYS A 1 61  ? 137.385 108.386 117.344 1.00 67.18  ? 42  LYS A CG  1 
ATOM   32   C CD  . LYS A 1 61  ? 138.891 108.389 117.521 1.00 67.18  ? 42  LYS A CD  1 
ATOM   33   C CE  . LYS A 1 61  ? 139.351 107.116 118.210 1.00 67.18  ? 42  LYS A CE  1 
ATOM   34   N NZ  . LYS A 1 61  ? 138.652 106.915 119.509 1.00 67.18  ? 42  LYS A NZ  1 
ATOM   35   N N   . LYS A 1 62  ? 136.883 108.049 113.195 1.00 66.79  ? 43  LYS A N   1 
ATOM   36   C CA  . LYS A 1 62  ? 136.305 106.951 112.424 1.00 66.79  ? 43  LYS A CA  1 
ATOM   37   C C   . LYS A 1 62  ? 136.167 105.689 113.268 1.00 66.79  ? 43  LYS A C   1 
ATOM   38   O O   . LYS A 1 62  ? 137.170 105.071 113.635 1.00 66.79  ? 43  LYS A O   1 
ATOM   39   C CB  . LYS A 1 62  ? 137.185 106.645 111.210 1.00 66.79  ? 43  LYS A CB  1 
ATOM   40   C CG  . LYS A 1 62  ? 137.431 107.821 110.280 1.00 66.79  ? 43  LYS A CG  1 
ATOM   41   C CD  . LYS A 1 62  ? 138.237 107.385 109.064 1.00 66.79  ? 43  LYS A CD  1 
ATOM   42   C CE  . LYS A 1 62  ? 138.458 108.526 108.089 1.00 66.79  ? 43  LYS A CE  1 
ATOM   43   N NZ  . LYS A 1 62  ? 139.174 108.065 106.869 1.00 66.79  ? 43  LYS A NZ  1 
ATOM   44   N N   . GLU A 1 63  ? 134.934 105.293 113.573 1.00 64.75  ? 44  GLU A N   1 
ATOM   45   C CA  . GLU A 1 63  ? 134.689 104.165 114.466 1.00 64.75  ? 44  GLU A CA  1 
ATOM   46   C C   . GLU A 1 63  ? 133.485 103.351 113.988 1.00 64.75  ? 44  GLU A C   1 
ATOM   47   O O   . GLU A 1 63  ? 132.605 102.979 114.765 1.00 64.75  ? 44  GLU A O   1 
ATOM   48   C CB  . GLU A 1 63  ? 134.515 104.664 115.900 1.00 64.75  ? 44  GLU A CB  1 
ATOM   49   C CG  . GLU A 1 63  ? 134.511 103.578 116.966 1.00 64.75  ? 44  GLU A CG  1 
ATOM   50   C CD  . GLU A 1 63  ? 135.870 103.373 117.601 1.00 64.75  ? 44  GLU A CD  1 
ATOM   51   O OE1 . GLU A 1 63  ? 136.860 103.932 117.086 1.00 64.75  ? 44  GLU A OE1 1 
ATOM   52   O OE2 . GLU A 1 63  ? 135.947 102.653 118.618 1.00 64.75  ? 44  GLU A OE2 1 
ATOM   53   N N   . ILE A 1 64  ? 133.412 103.081 112.688 1.00 55.05  ? 45  ILE A N   1 
ATOM   54   C CA  . ILE A 1 64  ? 132.352 102.257 112.118 1.00 55.05  ? 45  ILE A CA  1 
ATOM   55   C C   . ILE A 1 64  ? 132.997 101.119 111.342 1.00 55.05  ? 45  ILE A C   1 
ATOM   56   O O   . ILE A 1 64  ? 133.872 101.353 110.502 1.00 55.05  ? 45  ILE A O   1 
ATOM   57   C CB  . ILE A 1 64  ? 131.414 103.076 111.212 1.00 55.05  ? 45  ILE A CB  1 
ATOM   58   C CG1 . ILE A 1 64  ? 130.401 103.855 112.048 1.00 55.05  ? 45  ILE A CG1 1 
ATOM   59   C CG2 . ILE A 1 64  ? 130.681 102.172 110.246 1.00 55.05  ? 45  ILE A CG2 1 
ATOM   60   C CD1 . ILE A 1 64  ? 129.350 104.557 111.220 1.00 55.05  ? 45  ILE A CD1 1 
ATOM   61   N N   . SER A 1 65  ? 132.569 99.893  111.622 1.00 54.08  ? 46  SER A N   1 
ATOM   62   C CA  . SER A 1 65  ? 133.119 98.720  110.964 1.00 54.08  ? 46  SER A CA  1 
ATOM   63   C C   . SER A 1 65  ? 132.279 98.368  109.738 1.00 54.08  ? 46  SER A C   1 
ATOM   64   O O   . SER A 1 65  ? 131.412 99.133  109.309 1.00 54.08  ? 46  SER A O   1 
ATOM   65   C CB  . SER A 1 65  ? 133.198 97.552  111.944 1.00 54.08  ? 46  SER A CB  1 
ATOM   66   O OG  . SER A 1 65  ? 133.529 96.350  111.272 1.00 54.08  ? 46  SER A OG  1 
ATOM   67   N N   . LEU A 1 66  ? 132.536 97.195  109.157 1.00 48.34  ? 47  LEU A N   1 
ATOM   68   C CA  . LEU A 1 66  ? 131.717 96.711  108.051 1.00 48.34  ? 47  LEU A CA  1 
ATOM   69   C C   . LEU A 1 66  ? 130.358 96.230  108.537 1.00 48.34  ? 47  LEU A C   1 
ATOM   70   O O   . LEU A 1 66  ? 129.333 96.505  107.901 1.00 48.34  ? 47  LEU A O   1 
ATOM   71   C CB  . LEU A 1 66  ? 132.440 95.585  107.316 1.00 48.34  ? 47  LEU A CB  1 
ATOM   72   C CG  . LEU A 1 66  ? 131.567 94.650  106.485 1.00 48.34  ? 47  LEU A CG  1 
ATOM   73   C CD1 . LEU A 1 66  ? 130.947 95.384  105.317 1.00 48.34  ? 47  LEU A CD1 1 
ATOM   74   C CD2 . LEU A 1 66  ? 132.386 93.475  106.000 1.00 48.34  ? 47  LEU A CD2 1 
ATOM   75   N N   . LEU A 1 67  ? 130.334 95.507  109.656 1.00 44.36  ? 48  LEU A N   1 
ATOM   76   C CA  . LEU A 1 67  ? 129.066 95.037  110.193 1.00 44.36  ? 48  LEU A CA  1 
ATOM   77   C C   . LEU A 1 67  ? 128.184 96.203  110.606 1.00 44.36  ? 48  LEU A C   1 
ATOM   78   O O   . LEU A 1 67  ? 126.966 96.163  110.416 1.00 44.36  ? 48  LEU A O   1 
ATOM   79   C CB  . LEU A 1 67  ? 129.312 94.101  111.373 1.00 44.36  ? 48  LEU A CB  1 
ATOM   80   C CG  . LEU A 1 67  ? 128.123 93.267  111.835 1.00 44.36  ? 48  LEU A CG  1 
ATOM   81   C CD1 . LEU A 1 67  ? 128.600 91.914  112.317 1.00 44.36  ? 48  LEU A CD1 1 
ATOM   82   C CD2 . LEU A 1 67  ? 127.381 93.983  112.936 1.00 44.36  ? 48  LEU A CD2 1 
ATOM   83   N N   . ASN A 1 68  ? 128.781 97.265  111.148 1.00 43.23  ? 49  ASN A N   1 
ATOM   84   C CA  . ASN A 1 68  ? 127.984 98.419  111.545 1.00 43.23  ? 49  ASN A CA  1 
ATOM   85   C C   . ASN A 1 68  ? 127.435 99.158  110.333 1.00 43.23  ? 49  ASN A C   1 
ATOM   86   O O   . ASN A 1 68  ? 126.323 99.693  110.379 1.00 43.23  ? 49  ASN A O   1 
ATOM   87   C CB  . ASN A 1 68  ? 128.815 99.354  112.416 1.00 43.23  ? 49  ASN A CB  1 
ATOM   88   C CG  . ASN A 1 68  ? 128.557 99.148  113.885 1.00 43.23  ? 49  ASN A CG  1 
ATOM   89   O OD1 . ASN A 1 68  ? 127.415 99.207  114.333 1.00 43.23  ? 49  ASN A OD1 1 
ATOM   90   N ND2 . ASN A 1 68  ? 129.615 98.899  114.647 1.00 43.23  ? 49  ASN A ND2 1 
ATOM   91   N N   . GLY A 1 69  ? 128.179 99.171  109.229 1.00 39.61  ? 50  GLY A N   1 
ATOM   92   C CA  . GLY A 1 69  ? 127.658 99.782  108.017 1.00 39.61  ? 50  GLY A CA  1 
ATOM   93   C C   . GLY A 1 69  ? 126.524 98.984  107.402 1.00 39.61  ? 50  GLY A C   1 
ATOM   94   O O   . GLY A 1 69  ? 125.504 99.550  106.984 1.00 39.61  ? 50  GLY A O   1 
ATOM   95   N N   . VAL A 1 70  ? 126.691 97.661  107.320 1.00 38.80  ? 51  VAL A N   1 
ATOM   96   C CA  . VAL A 1 70  ? 125.599 96.803  106.872 1.00 38.80  ? 51  VAL A CA  1 
ATOM   97   C C   . VAL A 1 70  ? 124.386 96.990  107.766 1.00 38.80  ? 51  VAL A C   1 
ATOM   98   O O   . VAL A 1 70  ? 123.245 97.044  107.291 1.00 38.80  ? 51  VAL A O   1 
ATOM   99   C CB  . VAL A 1 70  ? 126.050 95.335  106.841 1.00 38.80  ? 51  VAL A CB  1 
ATOM   100  C CG1 . VAL A 1 70  ? 124.855 94.419  106.902 1.00 38.80  ? 51  VAL A CG1 1 
ATOM   101  C CG2 . VAL A 1 70  ? 126.856 95.063  105.597 1.00 38.80  ? 51  VAL A CG2 1 
ATOM   102  N N   . SER A 1 71  ? 124.613 97.113  109.074 1.00 37.94  ? 52  SER A N   1 
ATOM   103  C CA  . SER A 1 71  ? 123.505 97.298  109.997 1.00 37.94  ? 52  SER A CA  1 
ATOM   104  C C   . SER A 1 71  ? 122.816 98.631  109.767 1.00 37.94  ? 52  SER A C   1 
ATOM   105  O O   . SER A 1 71  ? 121.589 98.699  109.785 1.00 37.94  ? 52  SER A O   1 
ATOM   106  C CB  . SER A 1 71  ? 123.993 97.187  111.438 1.00 37.94  ? 52  SER A CB  1 
ATOM   107  O OG  . SER A 1 71  ? 124.030 95.834  111.849 1.00 37.94  ? 52  SER A OG  1 
ATOM   108  N N   . LEU A 1 72  ? 123.576 99.695  109.507 1.00 33.26  ? 53  LEU A N   1 
ATOM   109  C CA  . LEU A 1 72  ? 122.943 100.979 109.221 1.00 33.26  ? 53  LEU A CA  1 
ATOM   110  C C   . LEU A 1 72  ? 122.067 100.896 107.979 1.00 33.26  ? 53  LEU A C   1 
ATOM   111  O O   . LEU A 1 72  ? 120.882 101.244 108.017 1.00 33.26  ? 53  LEU A O   1 
ATOM   112  C CB  . LEU A 1 72  ? 123.987 102.084 109.070 1.00 33.26  ? 53  LEU A CB  1 
ATOM   113  C CG  . LEU A 1 72  ? 124.618 102.617 110.349 1.00 33.26  ? 53  LEU A CG  1 
ATOM   114  C CD1 . LEU A 1 72  ? 125.673 103.645 110.024 1.00 33.26  ? 53  LEU A CD1 1 
ATOM   115  C CD2 . LEU A 1 72  ? 123.541 103.230 111.202 1.00 33.26  ? 53  LEU A CD2 1 
ATOM   116  N N   . VAL A 1 73  ? 122.632 100.435 106.862 1.00 33.83  ? 54  VAL A N   1 
ATOM   117  C CA  . VAL A 1 73  ? 121.847 100.384 105.628 1.00 33.83  ? 54  VAL A CA  1 
ATOM   118  C C   . VAL A 1 73  ? 120.606 99.518  105.818 1.00 33.83  ? 54  VAL A C   1 
ATOM   119  O O   . VAL A 1 73  ? 119.471 99.976  105.622 1.00 33.83  ? 54  VAL A O   1 
ATOM   120  C CB  . VAL A 1 73  ? 122.700 99.883  104.452 1.00 33.83  ? 54  VAL A CB  1 
ATOM   121  C CG1 . VAL A 1 73  ? 121.930 100.035 103.173 1.00 33.83  ? 54  VAL A CG1 1 
ATOM   122  C CG2 . VAL A 1 73  ? 123.979 100.643 104.366 1.00 33.83  ? 54  VAL A CG2 1 
ATOM   123  N N   . VAL A 1 74  ? 120.807 98.260  106.184 1.00 33.39  ? 55  VAL A N   1 
ATOM   124  C CA  . VAL A 1 74  ? 119.673 97.377  106.397 1.00 33.39  ? 55  VAL A CA  1 
ATOM   125  C C   . VAL A 1 74  ? 118.718 98.003  107.399 1.00 33.39  ? 55  VAL A C   1 
ATOM   126  O O   . VAL A 1 74  ? 117.516 98.100  107.145 1.00 33.39  ? 55  VAL A O   1 
ATOM   127  C CB  . VAL A 1 74  ? 120.119 95.995  106.900 1.00 33.39  ? 55  VAL A CB  1 
ATOM   128  C CG1 . VAL A 1 74  ? 118.916 95.183  107.357 1.00 33.39  ? 55  VAL A CG1 1 
ATOM   129  C CG2 . VAL A 1 74  ? 120.881 95.261  105.807 1.00 33.39  ? 55  VAL A CG2 1 
ATOM   130  N N   . GLY A 1 75  ? 119.252 98.448  108.531 1.00 36.38  ? 56  GLY A N   1 
ATOM   131  C CA  . GLY A 1 75  ? 118.421 99.045  109.562 1.00 36.38  ? 56  GLY A CA  1 
ATOM   132  C C   . GLY A 1 75  ? 117.669 100.282 109.117 1.00 36.38  ? 56  GLY A C   1 
ATOM   133  O O   . GLY A 1 75  ? 116.691 100.675 109.751 1.00 36.38  ? 56  GLY A O   1 
ATOM   134  N N   . ASN A 1 76  ? 118.118 100.904 108.033 1.00 36.48  ? 57  ASN A N   1 
ATOM   135  C CA  . ASN A 1 76  ? 117.471 102.117 107.548 1.00 36.48  ? 57  ASN A CA  1 
ATOM   136  C C   . ASN A 1 76  ? 116.451 101.819 106.456 1.00 36.48  ? 57  ASN A C   1 
ATOM   137  O O   . ASN A 1 76  ? 115.554 102.622 106.203 1.00 36.48  ? 57  ASN A O   1 
ATOM   138  C CB  . ASN A 1 76  ? 118.510 103.108 107.030 1.00 36.48  ? 57  ASN A CB  1 
ATOM   139  C CG  . ASN A 1 76  ? 117.947 104.503 106.861 1.00 36.48  ? 57  ASN A CG  1 
ATOM   140  O OD1 . ASN A 1 76  ? 117.400 105.084 107.798 1.00 36.48  ? 57  ASN A OD1 1 
ATOM   141  N ND2 . ASN A 1 76  ? 118.079 105.048 105.663 1.00 36.48  ? 57  ASN A ND2 1 
ATOM   142  N N   . MET A 1 77  ? 116.587 100.670 105.806 1.00 41.96  ? 58  MET A N   1 
ATOM   143  C CA  . MET A 1 77  ? 115.663 100.310 104.734 1.00 41.96  ? 58  MET A CA  1 
ATOM   144  C C   . MET A 1 77  ? 114.484 99.511  105.273 1.00 41.96  ? 58  MET A C   1 
ATOM   145  O O   . MET A 1 77  ? 113.322 99.879  105.070 1.00 41.96  ? 58  MET A O   1 
ATOM   146  C CB  . MET A 1 77  ? 116.387 99.526  103.646 1.00 41.96  ? 58  MET A CB  1 
ATOM   147  C CG  . MET A 1 77  ? 117.434 100.321 102.933 1.00 41.96  ? 58  MET A CG  1 
ATOM   148  S SD  . MET A 1 77  ? 118.573 99.224  102.100 1.00 41.96  ? 58  MET A SD  1 
ATOM   149  C CE  . MET A 1 77  ? 117.602 98.781  100.667 1.00 41.96  ? 58  MET A CE  1 
ATOM   150  N N   . ILE A 1 78  ? 114.764 98.410  105.964 1.00 40.96  ? 59  ILE A N   1 
ATOM   151  C CA  . ILE A 1 78  ? 113.710 97.604  106.563 1.00 40.96  ? 59  ILE A CA  1 
ATOM   152  C C   . ILE A 1 78  ? 113.193 98.328  107.793 1.00 40.96  ? 59  ILE A C   1 
ATOM   153  O O   . ILE A 1 78  ? 113.774 98.224  108.877 1.00 40.96  ? 59  ILE A O   1 
ATOM   154  C CB  . ILE A 1 78  ? 114.213 96.200  106.936 1.00 40.96  ? 59  ILE A CB  1 
ATOM   155  C CG1 . ILE A 1 78  ? 114.895 95.536  105.748 1.00 40.96  ? 59  ILE A CG1 1 
ATOM   156  C CG2 . ILE A 1 78  ? 113.073 95.354  107.425 1.00 40.96  ? 59  ILE A CG2 1 
ATOM   157  C CD1 . ILE A 1 78  ? 115.300 94.114  106.015 1.00 40.96  ? 59  ILE A CD1 1 
ATOM   158  N N   . GLY A 1 79  ? 112.101 99.062  107.637 1.00 49.33  ? 60  GLY A N   1 
ATOM   159  C CA  . GLY A 1 79  ? 111.500 99.745  108.761 1.00 49.33  ? 60  GLY A CA  1 
ATOM   160  C C   . GLY A 1 79  ? 110.047 99.360  108.905 1.00 49.33  ? 60  GLY A C   1 
ATOM   161  O O   . GLY A 1 79  ? 109.689 98.189  108.751 1.00 49.33  ? 60  GLY A O   1 
ATOM   162  N N   . SER A 1 80  ? 109.197 100.338 109.195 1.00 55.12  ? 61  SER A N   1 
ATOM   163  C CA  . SER A 1 80  ? 107.764 100.105 109.136 1.00 55.12  ? 61  SER A CA  1 
ATOM   164  C C   . SER A 1 80  ? 107.237 100.082 107.711 1.00 55.12  ? 61  SER A C   1 
ATOM   165  O O   . SER A 1 80  ? 106.020 100.072 107.525 1.00 55.12  ? 61  SER A O   1 
ATOM   166  C CB  . SER A 1 80  ? 107.027 101.175 109.938 1.00 55.12  ? 61  SER A CB  1 
ATOM   167  O OG  . SER A 1 80  ? 106.779 102.318 109.141 1.00 55.12  ? 61  SER A OG  1 
ATOM   168  N N   . GLY A 1 81  ? 108.112 100.075 106.704 1.00 66.27  ? 62  GLY A N   1 
ATOM   169  C CA  . GLY A 1 81  ? 107.657 100.090 105.327 1.00 66.27  ? 62  GLY A CA  1 
ATOM   170  C C   . GLY A 1 81  ? 107.330 98.724  104.769 1.00 66.27  ? 62  GLY A C   1 
ATOM   171  O O   . GLY A 1 81  ? 106.744 98.635  103.687 1.00 66.27  ? 62  GLY A O   1 
ATOM   172  N N   . ILE A 1 82  ? 107.695 97.660  105.477 1.00 59.48  ? 63  ILE A N   1 
ATOM   173  C CA  . ILE A 1 82  ? 107.373 96.308  105.044 1.00 59.48  ? 63  ILE A CA  1 
ATOM   174  C C   . ILE A 1 82  ? 106.399 95.609  105.982 1.00 59.48  ? 63  ILE A C   1 
ATOM   175  O O   . ILE A 1 82  ? 105.806 94.594  105.585 1.00 59.48  ? 63  ILE A O   1 
ATOM   176  C CB  . ILE A 1 82  ? 108.646 95.457  104.869 1.00 59.48  ? 63  ILE A CB  1 
ATOM   177  C CG1 . ILE A 1 82  ? 108.381 94.291  103.922 1.00 59.48  ? 63  ILE A CG1 1 
ATOM   178  C CG2 . ILE A 1 82  ? 109.124 94.931  106.202 1.00 59.48  ? 63  ILE A CG2 1 
ATOM   179  C CD1 . ILE A 1 82  ? 107.763 94.712  102.616 1.00 59.48  ? 63  ILE A CD1 1 
ATOM   180  N N   . PHE A 1 83  ? 106.203 96.111  107.198 1.00 59.13  ? 64  PHE A N   1 
ATOM   181  C CA  . PHE A 1 83  ? 105.310 95.466  108.150 1.00 59.13  ? 64  PHE A CA  1 
ATOM   182  C C   . PHE A 1 83  ? 103.899 96.028  108.126 1.00 59.13  ? 64  PHE A C   1 
ATOM   183  O O   . PHE A 1 83  ? 102.943 95.281  108.342 1.00 59.13  ? 64  PHE A O   1 
ATOM   184  C CB  . PHE A 1 83  ? 105.859 95.589  109.573 1.00 59.13  ? 64  PHE A CB  1 
ATOM   185  C CG  . PHE A 1 83  ? 107.158 94.870  109.800 1.00 59.13  ? 64  PHE A CG  1 
ATOM   186  C CD1 . PHE A 1 83  ? 107.178 93.517  110.069 1.00 59.13  ? 64  PHE A CD1 1 
ATOM   187  C CD2 . PHE A 1 83  ? 108.357 95.558  109.775 1.00 59.13  ? 64  PHE A CD2 1 
ATOM   188  C CE1 . PHE A 1 83  ? 108.367 92.866  110.288 1.00 59.13  ? 64  PHE A CE1 1 
ATOM   189  C CE2 . PHE A 1 83  ? 109.546 94.910  109.993 1.00 59.13  ? 64  PHE A CE2 1 
ATOM   190  C CZ  . PHE A 1 83  ? 109.550 93.566  110.251 1.00 59.13  ? 64  PHE A CZ  1 
ATOM   191  N N   . VAL A 1 84  ? 103.728 97.323  107.874 1.00 63.34  ? 65  VAL A N   1 
ATOM   192  C CA  . VAL A 1 84  ? 102.401 97.914  107.975 1.00 63.34  ? 65  VAL A CA  1 
ATOM   193  C C   . VAL A 1 84  ? 101.754 98.149  106.616 1.00 63.34  ? 65  VAL A C   1 
ATOM   194  O O   . VAL A 1 84  ? 100.521 98.263  106.546 1.00 63.34  ? 65  VAL A O   1 
ATOM   195  C CB  . VAL A 1 84  ? 102.432 99.236  108.770 1.00 63.34  ? 65  VAL A CB  1 
ATOM   196  C CG1 . VAL A 1 84  ? 103.164 99.046  110.084 1.00 63.34  ? 65  VAL A CG1 1 
ATOM   197  C CG2 . VAL A 1 84  ? 103.024 100.360 107.948 1.00 63.34  ? 65  VAL A CG2 1 
ATOM   198  N N   . SER A 1 85  ? 102.532 98.220  105.543 1.00 69.28  ? 66  SER A N   1 
ATOM   199  C CA  . SER A 1 85  ? 101.923 98.526  104.257 1.00 69.28  ? 66  SER A CA  1 
ATOM   200  C C   . SER A 1 85  ? 102.767 98.056  103.079 1.00 69.28  ? 66  SER A C   1 
ATOM   201  O O   . SER A 1 85  ? 103.373 98.884  102.387 1.00 69.28  ? 66  SER A O   1 
ATOM   202  C CB  . SER A 1 85  ? 101.673 100.029 104.142 1.00 69.28  ? 66  SER A CB  1 
ATOM   203  O OG  . SER A 1 85  ? 102.821 100.696 103.649 1.00 69.28  ? 66  SER A OG  1 
ATOM   204  N N   . PRO A 1 86  ? 102.846 96.742  102.816 1.00 68.74  ? 67  PRO A N   1 
ATOM   205  C CA  . PRO A 1 86  ? 103.271 96.253  101.502 1.00 68.74  ? 67  PRO A CA  1 
ATOM   206  C C   . PRO A 1 86  ? 102.098 96.158  100.530 1.00 68.74  ? 67  PRO A C   1 
ATOM   207  O O   . PRO A 1 86  ? 101.934 95.165  99.814  1.00 68.74  ? 67  PRO A O   1 
ATOM   208  C CB  . PRO A 1 86  ? 103.856 94.875  101.831 1.00 68.74  ? 67  PRO A CB  1 
ATOM   209  C CG  . PRO A 1 86  ? 103.009 94.408  102.950 1.00 68.74  ? 67  PRO A CG  1 
ATOM   210  C CD  . PRO A 1 86  ? 102.646 95.632  103.762 1.00 68.74  ? 67  PRO A CD  1 
ATOM   211  N N   . LYS A 1 87  ? 101.265 97.198  100.507 1.00 69.44  ? 68  LYS A N   1 
ATOM   212  C CA  . LYS A 1 87  ? 100.092 97.259  99.647  1.00 69.44  ? 68  LYS A CA  1 
ATOM   213  C C   . LYS A 1 87  ? 100.242 98.226  98.489  1.00 69.44  ? 68  LYS A C   1 
ATOM   214  O O   . LYS A 1 87  ? 99.550  98.069  97.482  1.00 69.44  ? 68  LYS A O   1 
ATOM   215  C CB  . LYS A 1 87  ? 98.853  97.665  100.452 1.00 69.44  ? 68  LYS A CB  1 
ATOM   216  C CG  . LYS A 1 87  ? 98.535  96.765  101.622 1.00 69.44  ? 68  LYS A CG  1 
ATOM   217  C CD  . LYS A 1 87  ? 97.524  97.422  102.546 1.00 69.44  ? 68  LYS A CD  1 
ATOM   218  C CE  . LYS A 1 87  ? 98.137  98.574  103.319 1.00 69.44  ? 68  LYS A CE  1 
ATOM   219  N NZ  . LYS A 1 87  ? 97.265  98.999  104.446 1.00 69.44  ? 68  LYS A NZ  1 
ATOM   220  N N   . GLY A 1 88  ? 101.115 99.228  98.617  1.00 71.64  ? 69  GLY A N   1 
ATOM   221  C CA  . GLY A 1 88  ? 101.310 100.183 97.537  1.00 71.64  ? 69  GLY A CA  1 
ATOM   222  C C   . GLY A 1 88  ? 101.583 99.519  96.204  1.00 71.64  ? 69  GLY A C   1 
ATOM   223  O O   . GLY A 1 88  ? 101.270 100.067 95.145  1.00 71.64  ? 69  GLY A O   1 
ATOM   224  N N   . VAL A 1 89  ? 102.176 98.325  96.237  1.00 66.58  ? 70  VAL A N   1 
ATOM   225  C CA  . VAL A 1 89  ? 102.388 97.570  95.008  1.00 66.58  ? 70  VAL A CA  1 
ATOM   226  C C   . VAL A 1 89  ? 101.159 96.737  94.675  1.00 66.58  ? 70  VAL A C   1 
ATOM   227  O O   . VAL A 1 89  ? 100.710 96.696  93.524  1.00 66.58  ? 70  VAL A O   1 
ATOM   228  C CB  . VAL A 1 89  ? 103.642 96.691  95.133  1.00 66.58  ? 70  VAL A CB  1 
ATOM   229  C CG1 . VAL A 1 89  ? 103.811 95.855  93.891  1.00 66.58  ? 70  VAL A CG1 1 
ATOM   230  C CG2 . VAL A 1 89  ? 104.857 97.554  95.367  1.00 66.58  ? 70  VAL A CG2 1 
ATOM   231  N N   . LEU A 1 90  ? 100.597 96.058  95.675  1.00 67.59  ? 71  LEU A N   1 
ATOM   232  C CA  . LEU A 1 90  ? 99.462  95.177  95.425  1.00 67.59  ? 71  LEU A CA  1 
ATOM   233  C C   . LEU A 1 90  ? 98.216  95.953  95.022  1.00 67.59  ? 71  LEU A C   1 
ATOM   234  O O   . LEU A 1 90  ? 97.399  95.445  94.248  1.00 67.59  ? 71  LEU A O   1 
ATOM   235  C CB  . LEU A 1 90  ? 99.177  94.329  96.661  1.00 67.59  ? 71  LEU A CB  1 
ATOM   236  C CG  . LEU A 1 90  ? 98.300  93.106  96.422  1.00 67.59  ? 71  LEU A CG  1 
ATOM   237  C CD1 . LEU A 1 90  ? 98.808  92.349  95.224  1.00 67.59  ? 71  LEU A CD1 1 
ATOM   238  C CD2 . LEU A 1 90  ? 98.292  92.219  97.644  1.00 67.59  ? 71  LEU A CD2 1 
ATOM   239  N N   . VAL A 1 91  ? 98.049  97.177  95.526  1.00 70.31  ? 72  VAL A N   1 
ATOM   240  C CA  . VAL A 1 91  ? 96.846  97.933  95.211  1.00 70.31  ? 72  VAL A CA  1 
ATOM   241  C C   . VAL A 1 91  ? 96.840  98.387  93.758  1.00 70.31  ? 72  VAL A C   1 
ATOM   242  O O   . VAL A 1 91  ? 95.769  98.634  93.194  1.00 70.31  ? 72  VAL A O   1 
ATOM   243  C CB  . VAL A 1 91  ? 96.696  99.128  96.175  1.00 70.31  ? 72  VAL A CB  1 
ATOM   244  C CG1 . VAL A 1 91  ? 97.755  100.180 95.904  1.00 70.31  ? 72  VAL A CG1 1 
ATOM   245  C CG2 . VAL A 1 91  ? 95.297  99.721  96.100  1.00 70.31  ? 72  VAL A CG2 1 
ATOM   246  N N   . HIS A 1 92  ? 98.009  98.485  93.126  1.00 69.50  ? 73  HIS A N   1 
ATOM   247  C CA  . HIS A 1 92  ? 98.108  98.898  91.733  1.00 69.50  ? 73  HIS A CA  1 
ATOM   248  C C   . HIS A 1 92  ? 98.530  97.764  90.812  1.00 69.50  ? 73  HIS A C   1 
ATOM   249  O O   . HIS A 1 92  ? 98.916  98.022  89.669  1.00 69.50  ? 73  HIS A O   1 
ATOM   250  C CB  . HIS A 1 92  ? 99.079  100.070 91.596  1.00 69.50  ? 73  HIS A CB  1 
ATOM   251  C CG  . HIS A 1 92  ? 98.797  101.196 92.538  1.00 69.50  ? 73  HIS A CG  1 
ATOM   252  N ND1 . HIS A 1 92  ? 99.774  101.780 93.315  1.00 69.50  ? 73  HIS A ND1 1 
ATOM   253  C CD2 . HIS A 1 92  ? 97.645  101.841 92.834  1.00 69.50  ? 73  HIS A CD2 1 
ATOM   254  C CE1 . HIS A 1 92  ? 99.236  102.738 94.047  1.00 69.50  ? 73  HIS A CE1 1 
ATOM   255  N NE2 . HIS A 1 92  ? 97.945  102.796 93.774  1.00 69.50  ? 73  HIS A NE2 1 
ATOM   256  N N   . THR A 1 93  ? 98.484  96.517  91.280  1.00 72.75  ? 74  THR A N   1 
ATOM   257  C CA  . THR A 1 93  ? 98.822  95.387  90.424  1.00 72.75  ? 74  THR A CA  1 
ATOM   258  C C   . THR A 1 93  ? 97.776  94.283  90.534  1.00 72.75  ? 74  THR A C   1 
ATOM   259  O O   . THR A 1 93  ? 97.538  93.544  89.574  1.00 72.75  ? 74  THR A O   1 
ATOM   260  C CB  . THR A 1 93  ? 100.209 94.862  90.786  1.00 72.75  ? 74  THR A CB  1 
ATOM   261  O OG1 . THR A 1 93  ? 101.147 95.942  90.746  1.00 72.75  ? 74  THR A OG1 1 
ATOM   262  C CG2 . THR A 1 93  ? 100.643 93.808  89.809  1.00 72.75  ? 74  THR A CG2 1 
ATOM   263  N N   . ALA A 1 94  ? 97.145  94.175  91.703  1.00 77.35  ? 75  ALA A N   1 
ATOM   264  C CA  . ALA A 1 94  ? 95.984  93.309  91.924  1.00 77.35  ? 75  ALA A CA  1 
ATOM   265  C C   . ALA A 1 94  ? 96.245  91.851  91.551  1.00 77.35  ? 75  ALA A C   1 
ATOM   266  O O   . ALA A 1 94  ? 95.343  91.156  91.080  1.00 77.35  ? 75  ALA A O   1 
ATOM   267  C CB  . ALA A 1 94  ? 94.758  93.833  91.170  1.00 77.35  ? 75  ALA A CB  1 
ATOM   268  N N   . SER A 1 95  ? 97.467  91.365  91.758  1.00 79.22  ? 76  SER A N   1 
ATOM   269  C CA  . SER A 1 95  ? 97.766  89.948  91.585  1.00 79.22  ? 76  SER A CA  1 
ATOM   270  C C   . SER A 1 95  ? 99.058  89.624  92.316  1.00 79.22  ? 76  SER A C   1 
ATOM   271  O O   . SER A 1 95  ? 99.760  90.512  92.798  1.00 79.22  ? 76  SER A O   1 
ATOM   272  C CB  . SER A 1 95  ? 97.866  89.552  90.110  1.00 79.22  ? 76  SER A CB  1 
ATOM   273  O OG  . SER A 1 95  ? 96.722  89.968  89.393  1.00 79.22  ? 76  SER A OG  1 
ATOM   274  N N   . TYR A 1 96  ? 99.364  88.330  92.388  1.00 73.30  ? 77  TYR A N   1 
ATOM   275  C CA  . TYR A 1 96  ? 100.508 87.876  93.170  1.00 73.30  ? 77  TYR A CA  1 
ATOM   276  C C   . TYR A 1 96  ? 101.784 87.827  92.339  1.00 73.30  ? 77  TYR A C   1 
ATOM   277  O O   . TYR A 1 96  ? 102.807 88.402  92.720  1.00 73.30  ? 77  TYR A O   1 
ATOM   278  C CB  . TYR A 1 96  ? 100.211 86.505  93.775  1.00 73.30  ? 77  TYR A CB  1 
ATOM   279  C CG  . TYR A 1 96  ? 99.283  86.575  94.956  1.00 73.30  ? 77  TYR A CG  1 
ATOM   280  C CD1 . TYR A 1 96  ? 99.259  87.696  95.767  1.00 73.30  ? 77  TYR A CD1 1 
ATOM   281  C CD2 . TYR A 1 96  ? 98.431  85.527  95.259  1.00 73.30  ? 77  TYR A CD2 1 
ATOM   282  C CE1 . TYR A 1 96  ? 98.414  87.772  96.845  1.00 73.30  ? 77  TYR A CE1 1 
ATOM   283  C CE2 . TYR A 1 96  ? 97.583  85.595  96.338  1.00 73.30  ? 77  TYR A CE2 1 
ATOM   284  C CZ  . TYR A 1 96  ? 97.581  86.720  97.128  1.00 73.30  ? 77  TYR A CZ  1 
ATOM   285  O OH  . TYR A 1 96  ? 96.738  86.798  98.207  1.00 73.30  ? 77  TYR A OH  1 
ATOM   286  N N   . GLY A 1 97  ? 101.745 87.117  91.211  1.00 77.06  ? 78  GLY A N   1 
ATOM   287  C CA  . GLY A 1 97  ? 102.947 86.959  90.407  1.00 77.06  ? 78  GLY A CA  1 
ATOM   288  C C   . GLY A 1 97  ? 103.515 88.283  89.937  1.00 77.06  ? 78  GLY A C   1 
ATOM   289  O O   . GLY A 1 97  ? 104.715 88.544  90.068  1.00 77.06  ? 78  GLY A O   1 
ATOM   290  N N   . MET A 1 98  ? 102.657 89.146  89.391  1.00 75.70  ? 79  MET A N   1 
ATOM   291  C CA  . MET A 1 98  ? 103.141 90.431  88.905  1.00 75.70  ? 79  MET A CA  1 
ATOM   292  C C   . MET A 1 98  ? 103.537 91.350  90.053  1.00 75.70  ? 79  MET A C   1 
ATOM   293  O O   . MET A 1 98  ? 104.431 92.185  89.891  1.00 75.70  ? 79  MET A O   1 
ATOM   294  C CB  . MET A 1 98  ? 102.092 91.090  88.015  1.00 75.70  ? 79  MET A CB  1 
ATOM   295  C CG  . MET A 1 98  ? 102.579 92.350  87.330  1.00 75.70  ? 79  MET A CG  1 
ATOM   296  S SD  . MET A 1 98  ? 104.047 92.073  86.329  1.00 75.70  ? 79  MET A SD  1 
ATOM   297  C CE  . MET A 1 98  ? 103.339 91.247  84.908  1.00 75.70  ? 79  MET A CE  1 
ATOM   298  N N   . SER A 1 99  ? 102.929 91.186  91.231  1.00 67.27  ? 80  SER A N   1 
ATOM   299  C CA  . SER A 1 99  ? 103.373 91.964  92.384  1.00 67.27  ? 80  SER A CA  1 
ATOM   300  C C   . SER A 1 99  ? 104.772 91.549  92.820  1.00 67.27  ? 80  SER A C   1 
ATOM   301  O O   . SER A 1 99  ? 105.611 92.402  93.126  1.00 67.27  ? 80  SER A O   1 
ATOM   302  C CB  . SER A 1 99  ? 102.393 91.811  93.542  1.00 67.27  ? 80  SER A CB  1 
ATOM   303  O OG  . SER A 1 99  ? 102.562 92.850  94.486  1.00 67.27  ? 80  SER A OG  1 
ATOM   304  N N   . LEU A 1 100 ? 105.047 90.246  92.845  1.00 61.62  ? 81  LEU A N   1 
ATOM   305  C CA  . LEU A 1 100 ? 106.389 89.794  93.191  1.00 61.62  ? 81  LEU A CA  1 
ATOM   306  C C   . LEU A 1 100 ? 107.399 90.218  92.132  1.00 61.62  ? 81  LEU A C   1 
ATOM   307  O O   . LEU A 1 100 ? 108.542 90.562  92.457  1.00 61.62  ? 81  LEU A O   1 
ATOM   308  C CB  . LEU A 1 100 ? 106.401 88.281  93.372  1.00 61.62  ? 81  LEU A CB  1 
ATOM   309  C CG  . LEU A 1 100 ? 105.924 87.787  94.734  1.00 61.62  ? 81  LEU A CG  1 
ATOM   310  C CD1 . LEU A 1 100 ? 106.231 86.319  94.889  1.00 61.62  ? 81  LEU A CD1 1 
ATOM   311  C CD2 . LEU A 1 100 ? 106.581 88.585  95.830  1.00 61.62  ? 81  LEU A CD2 1 
ATOM   312  N N   . ILE A 1 101 ? 106.994 90.223  90.862  1.00 63.10  ? 82  ILE A N   1 
ATOM   313  C CA  . ILE A 1 101 ? 107.903 90.676  89.815  1.00 63.10  ? 82  ILE A CA  1 
ATOM   314  C C   . ILE A 1 101 ? 108.182 92.167  89.956  1.00 63.10  ? 82  ILE A C   1 
ATOM   315  O O   . ILE A 1 101 ? 109.313 92.622  89.748  1.00 63.10  ? 82  ILE A O   1 
ATOM   316  C CB  . ILE A 1 101 ? 107.340 90.331  88.426  1.00 63.10  ? 82  ILE A CB  1 
ATOM   317  C CG1 . ILE A 1 101 ? 107.327 88.816  88.229  1.00 63.10  ? 82  ILE A CG1 1 
ATOM   318  C CG2 . ILE A 1 101 ? 108.156 90.997  87.333  1.00 63.10  ? 82  ILE A CG2 1 
ATOM   319  C CD1 . ILE A 1 101 ? 108.604 88.137  88.662  1.00 63.10  ? 82  ILE A CD1 1 
ATOM   320  N N   . VAL A 1 102 ? 107.173 92.951  90.339  1.00 58.73  ? 83  VAL A N   1 
ATOM   321  C CA  . VAL A 1 102 ? 107.393 94.380  90.521  1.00 58.73  ? 83  VAL A CA  1 
ATOM   322  C C   . VAL A 1 102 ? 108.280 94.632  91.732  1.00 58.73  ? 83  VAL A C   1 
ATOM   323  O O   . VAL A 1 102 ? 109.126 95.531  91.719  1.00 58.73  ? 83  VAL A O   1 
ATOM   324  C CB  . VAL A 1 102 ? 106.050 95.120  90.632  1.00 58.73  ? 83  VAL A CB  1 
ATOM   325  C CG1 . VAL A 1 102 ? 106.241 96.485  91.263  1.00 58.73  ? 83  VAL A CG1 1 
ATOM   326  C CG2 . VAL A 1 102 ? 105.425 95.258  89.262  1.00 58.73  ? 83  VAL A CG2 1 
ATOM   327  N N   . TRP A 1 103 ? 108.127 93.829  92.785  1.00 54.43  ? 84  TRP A N   1 
ATOM   328  C CA  . TRP A 1 103 ? 109.029 93.939  93.927  1.00 54.43  ? 84  TRP A CA  1 
ATOM   329  C C   . TRP A 1 103 ? 110.465 93.642  93.515  1.00 54.43  ? 84  TRP A C   1 
ATOM   330  O O   . TRP A 1 103 ? 111.386 94.403  93.832  1.00 54.43  ? 84  TRP A O   1 
ATOM   331  C CB  . TRP A 1 103 ? 108.584 92.997  95.043  1.00 54.43  ? 84  TRP A CB  1 
ATOM   332  C CG  . TRP A 1 103 ? 107.577 93.595  95.954  1.00 54.43  ? 84  TRP A CG  1 
ATOM   333  C CD1 . TRP A 1 103 ? 106.241 93.356  95.957  1.00 54.43  ? 84  TRP A CD1 1 
ATOM   334  C CD2 . TRP A 1 103 ? 107.820 94.527  97.012  1.00 54.43  ? 84  TRP A CD2 1 
ATOM   335  N NE1 . TRP A 1 103 ? 105.630 94.090  96.940  1.00 54.43  ? 84  TRP A NE1 1 
ATOM   336  C CE2 . TRP A 1 103 ? 106.580 94.815  97.606  1.00 54.43  ? 84  TRP A CE2 1 
ATOM   337  C CE3 . TRP A 1 103 ? 108.966 95.149  97.511  1.00 54.43  ? 84  TRP A CE3 1 
ATOM   338  C CZ2 . TRP A 1 103 ? 106.451 95.696  98.675  1.00 54.43  ? 84  TRP A CZ2 1 
ATOM   339  C CZ3 . TRP A 1 103 ? 108.834 96.024  98.573  1.00 54.43  ? 84  TRP A CZ3 1 
ATOM   340  C CH2 . TRP A 1 103 ? 107.588 96.290  99.142  1.00 54.43  ? 84  TRP A CH2 1 
ATOM   341  N N   . ALA A 1 104 ? 110.670 92.541  92.789  1.00 54.19  ? 85  ALA A N   1 
ATOM   342  C CA  . ALA A 1 104 ? 112.012 92.191  92.334  1.00 54.19  ? 85  ALA A CA  1 
ATOM   343  C C   . ALA A 1 104 ? 112.610 93.282  91.454  1.00 54.19  ? 85  ALA A C   1 
ATOM   344  O O   . ALA A 1 104 ? 113.794 93.610  91.581  1.00 54.19  ? 85  ALA A O   1 
ATOM   345  C CB  . ALA A 1 104 ? 111.981 90.860  91.586  1.00 54.19  ? 85  ALA A CB  1 
ATOM   346  N N   . ILE A 1 105 ? 111.811 93.871  90.566  1.00 53.58  ? 86  ILE A N   1 
ATOM   347  C CA  . ILE A 1 105 ? 112.372 94.825  89.615  1.00 53.58  ? 86  ILE A CA  1 
ATOM   348  C C   . ILE A 1 105 ? 112.626 96.176  90.276  1.00 53.58  ? 86  ILE A C   1 
ATOM   349  O O   . ILE A 1 105 ? 113.636 96.837  89.994  1.00 53.58  ? 86  ILE A O   1 
ATOM   350  C CB  . ILE A 1 105 ? 111.454 94.942  88.389  1.00 53.58  ? 86  ILE A CB  1 
ATOM   351  C CG1 . ILE A 1 105 ? 111.498 93.643  87.586  1.00 53.58  ? 86  ILE A CG1 1 
ATOM   352  C CG2 . ILE A 1 105 ? 111.866 96.113  87.519  1.00 53.58  ? 86  ILE A CG2 1 
ATOM   353  C CD1 . ILE A 1 105 ? 110.594 93.638  86.380  1.00 53.58  ? 86  ILE A CD1 1 
ATOM   354  N N   . GLY A 1 106 ? 111.732 96.614  91.163  1.00 50.92  ? 87  GLY A N   1 
ATOM   355  C CA  . GLY A 1 106 ? 112.038 97.776  91.977  1.00 50.92  ? 87  GLY A CA  1 
ATOM   356  C C   . GLY A 1 106 ? 113.301 97.576  92.790  1.00 50.92  ? 87  GLY A C   1 
ATOM   357  O O   . GLY A 1 106 ? 114.111 98.495  92.938  1.00 50.92  ? 87  GLY A O   1 
ATOM   358  N N   . GLY A 1 107 ? 113.499 96.361  93.306  1.00 50.98  ? 88  GLY A N   1 
ATOM   359  C CA  . GLY A 1 107 ? 114.729 96.069  94.016  1.00 50.98  ? 88  GLY A CA  1 
ATOM   360  C C   . GLY A 1 107 ? 115.948 96.134  93.120  1.00 50.98  ? 88  GLY A C   1 
ATOM   361  O O   . GLY A 1 107 ? 117.005 96.607  93.532  1.00 50.98  ? 88  GLY A O   1 
ATOM   362  N N   . LEU A 1 108 ? 115.817 95.658  91.884  1.00 51.02  ? 89  LEU A N   1 
ATOM   363  C CA  . LEU A 1 108 ? 116.935 95.734  90.951  1.00 51.02  ? 89  LEU A CA  1 
ATOM   364  C C   . LEU A 1 108 ? 117.304 97.182  90.656  1.00 51.02  ? 89  LEU A C   1 
ATOM   365  O O   . LEU A 1 108 ? 118.489 97.537  90.609  1.00 51.02  ? 89  LEU A O   1 
ATOM   366  C CB  . LEU A 1 108 ? 116.590 94.998  89.661  1.00 51.02  ? 89  LEU A CB  1 
ATOM   367  C CG  . LEU A 1 108 ? 117.773 94.395  88.912  1.00 51.02  ? 89  LEU A CG  1 
ATOM   368  C CD1 . LEU A 1 108 ? 118.306 93.199  89.674  1.00 51.02  ? 89  LEU A CD1 1 
ATOM   369  C CD2 . LEU A 1 108 ? 117.367 94.003  87.506  1.00 51.02  ? 89  LEU A CD2 1 
ATOM   370  N N   . PHE A 1 109 ? 116.300 98.039  90.466  1.00 56.78  ? 90  PHE A N   1 
ATOM   371  C CA  . PHE A 1 109 ? 116.592 99.446  90.208  1.00 56.78  ? 90  PHE A CA  1 
ATOM   372  C C   . PHE A 1 109 ? 117.217 100.113 91.429  1.00 56.78  ? 90  PHE A C   1 
ATOM   373  O O   . PHE A 1 109 ? 118.163 100.903 91.300  1.00 56.78  ? 90  PHE A O   1 
ATOM   374  C CB  . PHE A 1 109 ? 115.325 100.180 89.779  1.00 56.78  ? 90  PHE A CB  1 
ATOM   375  C CG  . PHE A 1 109 ? 115.060 100.111 88.306  1.00 56.78  ? 90  PHE A CG  1 
ATOM   376  C CD1 . PHE A 1 109 ? 114.672 98.922  87.715  1.00 56.78  ? 90  PHE A CD1 1 
ATOM   377  C CD2 . PHE A 1 109 ? 115.196 101.235 87.511  1.00 56.78  ? 90  PHE A CD2 1 
ATOM   378  C CE1 . PHE A 1 109 ? 114.425 98.855  86.360  1.00 56.78  ? 90  PHE A CE1 1 
ATOM   379  C CE2 . PHE A 1 109 ? 114.951 101.176 86.156  1.00 56.78  ? 90  PHE A CE2 1 
ATOM   380  C CZ  . PHE A 1 109 ? 114.565 99.984  85.579  1.00 56.78  ? 90  PHE A CZ  1 
ATOM   381  N N   . SER A 1 110 ? 116.715 99.801  92.625  1.00 53.40  ? 91  SER A N   1 
ATOM   382  C CA  . SER A 1 110 ? 117.335 100.352 93.824  1.00 53.40  ? 91  SER A CA  1 
ATOM   383  C C   . SER A 1 110 ? 118.753 99.829  94.010  1.00 53.40  ? 91  SER A C   1 
ATOM   384  O O   . SER A 1 110 ? 119.598 100.531 94.567  1.00 53.40  ? 91  SER A O   1 
ATOM   385  C CB  . SER A 1 110 ? 116.489 100.039 95.053  1.00 53.40  ? 91  SER A CB  1 
ATOM   386  O OG  . SER A 1 110 ? 117.263 100.147 96.234  1.00 53.40  ? 91  SER A OG  1 
ATOM   387  N N   . VAL A 1 111 ? 119.041 98.615  93.544  1.00 51.43  ? 92  VAL A N   1 
ATOM   388  C CA  . VAL A 1 111 ? 120.403 98.100  93.629  1.00 51.43  ? 92  VAL A CA  1 
ATOM   389  C C   . VAL A 1 111 ? 121.313 98.852  92.670  1.00 51.43  ? 92  VAL A C   1 
ATOM   390  O O   . VAL A 1 111 ? 122.463 99.166  93.000  1.00 51.43  ? 92  VAL A O   1 
ATOM   391  C CB  . VAL A 1 111 ? 120.424 96.586  93.359  1.00 51.43  ? 92  VAL A CB  1 
ATOM   392  C CG1 . VAL A 1 111 ? 121.809 96.137  92.935  1.00 51.43  ? 92  VAL A CG1 1 
ATOM   393  C CG2 . VAL A 1 111 ? 119.980 95.835  94.592  1.00 51.43  ? 92  VAL A CG2 1 
ATOM   394  N N   . VAL A 1 112 ? 120.821 99.146  91.465  1.00 55.05  ? 93  VAL A N   1 
ATOM   395  C CA  . VAL A 1 112 ? 121.609 99.958  90.541  1.00 55.05  ? 93  VAL A CA  1 
ATOM   396  C C   . VAL A 1 112 ? 121.886 101.328 91.148  1.00 55.05  ? 93  VAL A C   1 
ATOM   397  O O   . VAL A 1 112 ? 122.992 101.873 91.025  1.00 55.05  ? 93  VAL A O   1 
ATOM   398  C CB  . VAL A 1 112 ? 120.901 100.071 89.180  1.00 55.05  ? 93  VAL A CB  1 
ATOM   399  C CG1 . VAL A 1 112 ? 121.700 100.958 88.264  1.00 55.05  ? 93  VAL A CG1 1 
ATOM   400  C CG2 . VAL A 1 112 ? 120.729 98.699  88.556  1.00 55.05  ? 93  VAL A CG2 1 
ATOM   401  N N   . GLY A 1 113 ? 120.904 101.885 91.854  1.00 54.94  ? 94  GLY A N   1 
ATOM   402  C CA  . GLY A 1 113 ? 121.130 103.154 92.531  1.00 54.94  ? 94  GLY A CA  1 
ATOM   403  C C   . GLY A 1 113 ? 122.142 103.052 93.659  1.00 54.94  ? 94  GLY A C   1 
ATOM   404  O O   . GLY A 1 113 ? 122.990 103.933 93.832  1.00 54.94  ? 94  GLY A O   1 
ATOM   405  N N   . ALA A 1 114 ? 122.056 101.990 94.455  1.00 50.89  ? 95  ALA A N   1 
ATOM   406  C CA  . ALA A 1 114 ? 123.023 101.797 95.525  1.00 50.89  ? 95  ALA A CA  1 
ATOM   407  C C   . ALA A 1 114 ? 124.432 101.627 94.983  1.00 50.89  ? 95  ALA A C   1 
ATOM   408  O O   . ALA A 1 114 ? 125.390 102.067 95.618  1.00 50.89  ? 95  ALA A O   1 
ATOM   409  C CB  . ALA A 1 114 ? 122.632 100.596 96.376  1.00 50.89  ? 95  ALA A CB  1 
ATOM   410  N N   . LEU A 1 115 ? 124.583 100.991 93.821  1.00 53.19  ? 96  LEU A N   1 
ATOM   411  C CA  . LEU A 1 115 ? 125.910 100.885 93.221  1.00 53.19  ? 96  LEU A CA  1 
ATOM   412  C C   . LEU A 1 115 ? 126.391 102.238 92.714  1.00 53.19  ? 96  LEU A C   1 
ATOM   413  O O   . LEU A 1 115 ? 127.581 102.569 92.825  1.00 53.19  ? 96  LEU A O   1 
ATOM   414  C CB  . LEU A 1 115 ? 125.893 99.861  92.093  1.00 53.19  ? 96  LEU A CB  1 
ATOM   415  C CG  . LEU A 1 115 ? 126.015 98.418  92.564  1.00 53.19  ? 96  LEU A CG  1 
ATOM   416  C CD1 . LEU A 1 115 ? 125.962 97.473  91.383  1.00 53.19  ? 96  LEU A CD1 1 
ATOM   417  C CD2 . LEU A 1 115 ? 127.301 98.242  93.340  1.00 53.19  ? 96  LEU A CD2 1 
ATOM   418  N N   . CYS A 1 116 ? 125.477 103.032 92.153  1.00 57.92  ? 97  CYS A N   1 
ATOM   419  C CA  . CYS A 1 116 ? 125.781 104.428 91.863  1.00 57.92  ? 97  CYS A CA  1 
ATOM   420  C C   . CYS A 1 116 ? 126.362 105.128 93.086  1.00 57.92  ? 97  CYS A C   1 
ATOM   421  O O   . CYS A 1 116 ? 127.395 105.806 93.005  1.00 57.92  ? 97  CYS A O   1 
ATOM   422  C CB  . CYS A 1 116 ? 124.513 105.134 91.387  1.00 57.92  ? 97  CYS A CB  1 
ATOM   423  S SG  . CYS A 1 116 ? 124.688 106.883 91.058  1.00 57.92  ? 97  CYS A SG  1 
ATOM   424  N N   . TYR A 1 117 ? 125.721 104.953 94.242  1.00 48.20  ? 98  TYR A N   1 
ATOM   425  C CA  . TYR A 1 117 ? 126.203 105.646 95.434  1.00 48.20  ? 98  TYR A CA  1 
ATOM   426  C C   . TYR A 1 117 ? 127.467 105.022 96.000  1.00 48.20  ? 98  TYR A C   1 
ATOM   427  O O   . TYR A 1 117 ? 128.241 105.715 96.656  1.00 48.20  ? 98  TYR A O   1 
ATOM   428  C CB  . TYR A 1 117 ? 125.135 105.714 96.520  1.00 48.20  ? 98  TYR A CB  1 
ATOM   429  C CG  . TYR A 1 117 ? 124.398 107.025 96.528  1.00 48.20  ? 98  TYR A CG  1 
ATOM   430  C CD1 . TYR A 1 117 ? 124.579 107.944 95.517  1.00 48.20  ? 98  TYR A CD1 1 
ATOM   431  C CD2 . TYR A 1 117 ? 123.564 107.363 97.569  1.00 48.20  ? 98  TYR A CD2 1 
ATOM   432  C CE1 . TYR A 1 117 ? 123.918 109.141 95.525  1.00 48.20  ? 98  TYR A CE1 1 
ATOM   433  C CE2 . TYR A 1 117 ? 122.903 108.557 97.586  1.00 48.20  ? 98  TYR A CE2 1 
ATOM   434  C CZ  . TYR A 1 117 ? 123.082 109.443 96.565  1.00 48.20  ? 98  TYR A CZ  1 
ATOM   435  O OH  . TYR A 1 117 ? 122.417 110.643 96.587  1.00 48.20  ? 98  TYR A OH  1 
ATOM   436  N N   . ALA A 1 118 ? 127.693 103.730 95.790  1.00 53.37  ? 99  ALA A N   1 
ATOM   437  C CA  . ALA A 1 118 ? 128.987 103.168 96.155  1.00 53.37  ? 99  ALA A CA  1 
ATOM   438  C C   . ALA A 1 118 ? 130.096 103.851 95.370  1.00 53.37  ? 99  ALA A C   1 
ATOM   439  O O   . ALA A 1 118 ? 131.104 104.295 95.940  1.00 53.37  ? 99  ALA A O   1 
ATOM   440  C CB  . ALA A 1 118 ? 129.003 101.658 95.921  1.00 53.37  ? 99  ALA A CB  1 
ATOM   441  N N   . GLU A 1 119 ? 129.904 103.986 94.056  1.00 63.68  ? 100 GLU A N   1 
ATOM   442  C CA  . GLU A 1 119 ? 130.891 104.694 93.248  1.00 63.68  ? 100 GLU A CA  1 
ATOM   443  C C   . GLU A 1 119 ? 131.084 106.119 93.746  1.00 63.68  ? 100 GLU A C   1 
ATOM   444  O O   . GLU A 1 119 ? 132.221 106.581 93.907  1.00 63.68  ? 100 GLU A O   1 
ATOM   445  C CB  . GLU A 1 119 ? 130.477 104.699 91.780  1.00 63.68  ? 100 GLU A CB  1 
ATOM   446  C CG  . GLU A 1 119 ? 131.320 105.632 90.931  1.00 63.68  ? 100 GLU A CG  1 
ATOM   447  C CD  . GLU A 1 119 ? 131.100 105.436 89.448  1.00 63.68  ? 100 GLU A CD  1 
ATOM   448  O OE1 . GLU A 1 119 ? 130.814 104.295 89.030  1.00 63.68  ? 100 GLU A OE1 1 
ATOM   449  O OE2 . GLU A 1 119 ? 131.211 106.428 88.698  1.00 63.68  ? 100 GLU A OE2 1 
ATOM   450  N N   . LEU A 1 120 ? 129.986 106.826 94.013  1.00 58.90  ? 101 LEU A N   1 
ATOM   451  C CA  . LEU A 1 120 ? 130.095 108.201 94.491  1.00 58.90  ? 101 LEU A CA  1 
ATOM   452  C C   . LEU A 1 120 ? 130.840 108.264 95.821  1.00 58.90  ? 101 LEU A C   1 
ATOM   453  O O   . LEU A 1 120 ? 131.915 108.864 95.920  1.00 58.90  ? 101 LEU A O   1 
ATOM   454  C CB  . LEU A 1 120 ? 128.708 108.827 94.614  1.00 58.90  ? 101 LEU A CB  1 
ATOM   455  C CG  . LEU A 1 120 ? 128.326 109.701 93.425  1.00 58.90  ? 101 LEU A CG  1 
ATOM   456  C CD1 . LEU A 1 120 ? 126.975 110.329 93.654  1.00 58.90  ? 101 LEU A CD1 1 
ATOM   457  C CD2 . LEU A 1 120 ? 129.384 110.761 93.204  1.00 58.90  ? 101 LEU A CD2 1 
ATOM   458  N N   . GLY A 1 121 ? 130.290 107.625 96.854  1.00 58.40  ? 102 GLY A N   1 
ATOM   459  C CA  . GLY A 1 121 ? 130.862 107.615 98.187  1.00 58.40  ? 102 GLY A CA  1 
ATOM   460  C C   . GLY A 1 121 ? 132.242 107.008 98.281  1.00 58.40  ? 102 GLY A C   1 
ATOM   461  O O   . GLY A 1 121 ? 132.835 107.042 99.363  1.00 58.40  ? 102 GLY A O   1 
ATOM   462  N N   . THR A 1 122 ? 132.765 106.445 97.198  1.00 59.92  ? 103 THR A N   1 
ATOM   463  C CA  . THR A 1 122 ? 134.194 106.180 97.171  1.00 59.92  ? 103 THR A CA  1 
ATOM   464  C C   . THR A 1 122 ? 134.974 107.176 96.328  1.00 59.92  ? 103 THR A C   1 
ATOM   465  O O   . THR A 1 122 ? 136.196 107.261 96.479  1.00 59.92  ? 103 THR A O   1 
ATOM   466  C CB  . THR A 1 122 ? 134.470 104.764 96.668  1.00 59.92  ? 103 THR A CB  1 
ATOM   467  O OG1 . THR A 1 122 ? 133.552 104.441 95.617  1.00 59.92  ? 103 THR A OG1 1 
ATOM   468  C CG2 . THR A 1 122 ? 134.326 103.780 97.800  1.00 59.92  ? 103 THR A CG2 1 
ATOM   469  N N   . THR A 1 123 ? 134.309 107.948 95.467  1.00 65.00  ? 104 THR A N   1 
ATOM   470  C CA  . THR A 1 123 ? 135.020 108.993 94.737  1.00 65.00  ? 104 THR A CA  1 
ATOM   471  C C   . THR A 1 123 ? 135.303 110.192 95.632  1.00 65.00  ? 104 THR A C   1 
ATOM   472  O O   . THR A 1 123 ? 136.448 110.648 95.734  1.00 65.00  ? 104 THR A O   1 
ATOM   473  C CB  . THR A 1 123 ? 134.220 109.431 93.514  1.00 65.00  ? 104 THR A CB  1 
ATOM   474  O OG1 . THR A 1 123 ? 132.848 109.610 93.880  1.00 65.00  ? 104 THR A OG1 1 
ATOM   475  C CG2 . THR A 1 123 ? 134.315 108.391 92.418  1.00 65.00  ? 104 THR A CG2 1 
ATOM   476  N N   . ILE A 1 124 ? 134.272 110.714 96.290  1.00 63.12  ? 105 ILE A N   1 
ATOM   477  C CA  . ILE A 1 124 ? 134.383 111.977 97.016  1.00 63.12  ? 105 ILE A CA  1 
ATOM   478  C C   . ILE A 1 124 ? 134.909 111.770 98.430  1.00 63.12  ? 105 ILE A C   1 
ATOM   479  O O   . ILE A 1 124 ? 135.813 112.483 98.872  1.00 63.12  ? 105 ILE A O   1 
ATOM   480  C CB  . ILE A 1 124 ? 133.024 112.707 97.013  1.00 63.12  ? 105 ILE A CB  1 
ATOM   481  C CG1 . ILE A 1 124 ? 132.840 113.466 95.702  1.00 63.12  ? 105 ILE A CG1 1 
ATOM   482  C CG2 . ILE A 1 124 ? 132.929 113.665 98.172  1.00 63.12  ? 105 ILE A CG2 1 
ATOM   483  C CD1 . ILE A 1 124 ? 131.551 114.234 95.617  1.00 63.12  ? 105 ILE A CD1 1 
ATOM   484  N N   . THR A 1 125 ? 134.360 110.796 99.157  1.00 62.03  ? 106 THR A N   1 
ATOM   485  C CA  . THR A 1 125 ? 134.724 110.528 100.550 1.00 62.03  ? 106 THR A CA  1 
ATOM   486  C C   . THR A 1 125 ? 134.474 111.765 101.418 1.00 62.03  ? 106 THR A C   1 
ATOM   487  O O   . THR A 1 125 ? 135.392 112.400 101.939 1.00 62.03  ? 106 THR A O   1 
ATOM   488  C CB  . THR A 1 125 ? 136.176 110.048 100.664 1.00 62.03  ? 106 THR A CB  1 
ATOM   489  O OG1 . THR A 1 125 ? 136.389 108.960 99.763  1.00 62.03  ? 106 THR A OG1 1 
ATOM   490  C CG2 . THR A 1 125 ? 136.462 109.549 102.072 1.00 62.03  ? 106 THR A CG2 1 
ATOM   491  N N   . LYS A 1 126 ? 133.196 112.120 101.530 1.00 55.74  ? 107 LYS A N   1 
ATOM   492  C CA  . LYS A 1 126 ? 132.772 113.228 102.372 1.00 55.74  ? 107 LYS A CA  1 
ATOM   493  C C   . LYS A 1 126 ? 131.325 112.991 102.772 1.00 55.74  ? 107 LYS A C   1 
ATOM   494  O O   . LYS A 1 126 ? 130.509 112.584 101.945 1.00 55.74  ? 107 LYS A O   1 
ATOM   495  C CB  . LYS A 1 126 ? 132.925 114.566 101.648 1.00 55.74  ? 107 LYS A CB  1 
ATOM   496  C CG  . LYS A 1 126 ? 132.812 115.778 102.540 1.00 55.74  ? 107 LYS A CG  1 
ATOM   497  C CD  . LYS A 1 126 ? 133.003 117.054 101.739 1.00 55.74  ? 107 LYS A CD  1 
ATOM   498  C CE  . LYS A 1 126 ? 134.226 116.959 100.841 1.00 55.74  ? 107 LYS A CE  1 
ATOM   499  N NZ  . LYS A 1 126 ? 134.174 117.943 99.725  1.00 55.74  ? 107 LYS A NZ  1 
ATOM   500  N N   . SER A 1 127 ? 131.021 113.240 104.041 1.00 48.88  ? 108 SER A N   1 
ATOM   501  C CA  . SER A 1 127 ? 129.732 112.863 104.598 1.00 48.88  ? 108 SER A CA  1 
ATOM   502  C C   . SER A 1 127 ? 128.588 113.618 103.928 1.00 48.88  ? 108 SER A C   1 
ATOM   503  O O   . SER A 1 127 ? 128.770 114.670 103.314 1.00 48.88  ? 108 SER A O   1 
ATOM   504  C CB  . SER A 1 127 ? 129.700 113.123 106.103 1.00 48.88  ? 108 SER A CB  1 
ATOM   505  O OG  . SER A 1 127 ? 130.901 112.723 106.728 1.00 48.88  ? 108 SER A OG  1 
ATOM   506  N N   . GLY A 1 128 ? 127.393 113.054 104.056 1.00 46.31  ? 109 GLY A N   1 
ATOM   507  C CA  . GLY A 1 128 ? 126.169 113.705 103.637 1.00 46.31  ? 109 GLY A CA  1 
ATOM   508  C C   . GLY A 1 128 ? 125.495 113.036 102.459 1.00 46.31  ? 109 GLY A C   1 
ATOM   509  O O   . GLY A 1 128 ? 124.274 112.863 102.451 1.00 46.31  ? 109 GLY A O   1 
ATOM   510  N N   . ALA A 1 129 ? 126.279 112.680 101.447 1.00 49.38  ? 110 ALA A N   1 
ATOM   511  C CA  . ALA A 1 129 ? 125.840 111.844 100.335 1.00 49.38  ? 110 ALA A CA  1 
ATOM   512  C C   . ALA A 1 129 ? 124.753 112.473 99.475  1.00 49.38  ? 110 ALA A C   1 
ATOM   513  O O   . ALA A 1 129 ? 124.387 111.921 98.435  1.00 49.38  ? 110 ALA A O   1 
ATOM   514  C CB  . ALA A 1 129 ? 125.339 110.502 100.852 1.00 49.38  ? 110 ALA A CB  1 
ATOM   515  N N   . SER A 1 130 ? 124.215 113.603 99.896  1.00 45.66  ? 111 SER A N   1 
ATOM   516  C CA  . SER A 1 130 ? 123.393 114.412 99.016  1.00 45.66  ? 111 SER A CA  1 
ATOM   517  C C   . SER A 1 130 ? 123.577 115.895 99.273  1.00 45.66  ? 111 SER A C   1 
ATOM   518  O O   . SER A 1 130 ? 122.865 116.702 98.671  1.00 45.66  ? 111 SER A O   1 
ATOM   519  C CB  . SER A 1 130 ? 121.917 114.031 99.149  1.00 45.66  ? 111 SER A CB  1 
ATOM   520  O OG  . SER A 1 130 ? 121.653 112.828 98.453  1.00 45.66  ? 111 SER A OG  1 
ATOM   521  N N   . TYR A 1 131 ? 124.498 116.275 100.151 1.00 43.50  ? 112 TYR A N   1 
ATOM   522  C CA  . TYR A 1 131 ? 124.826 117.663 100.420 1.00 43.50  ? 112 TYR A CA  1 
ATOM   523  C C   . TYR A 1 131 ? 126.276 117.972 100.096 1.00 43.50  ? 112 TYR A C   1 
ATOM   524  O O   . TYR A 1 131 ? 126.646 119.136 99.944  1.00 43.50  ? 112 TYR A O   1 
ATOM   525  C CB  . TYR A 1 131 ? 124.538 117.992 101.885 1.00 43.50  ? 112 TYR A CB  1 
ATOM   526  C CG  . TYR A 1 131 ? 125.080 119.318 102.320 1.00 43.50  ? 112 TYR A CG  1 
ATOM   527  C CD1 . TYR A 1 131 ? 124.614 120.491 101.765 1.00 43.50  ? 112 TYR A CD1 1 
ATOM   528  C CD2 . TYR A 1 131 ? 126.086 119.396 103.258 1.00 43.50  ? 112 TYR A CD2 1 
ATOM   529  C CE1 . TYR A 1 131 ? 125.118 121.704 102.153 1.00 43.50  ? 112 TYR A CE1 1 
ATOM   530  C CE2 . TYR A 1 131 ? 126.598 120.603 103.649 1.00 43.50  ? 112 TYR A CE2 1 
ATOM   531  C CZ  . TYR A 1 131 ? 126.111 121.756 103.096 1.00 43.50  ? 112 TYR A CZ  1 
ATOM   532  O OH  . TYR A 1 131 ? 126.624 122.967 103.488 1.00 43.50  ? 112 TYR A OH  1 
ATOM   533  N N   . ALA A 1 132 ? 127.111 116.945 99.974  1.00 49.61  ? 113 ALA A N   1 
ATOM   534  C CA  . ALA A 1 132 ? 128.465 117.162 99.486  1.00 49.61  ? 113 ALA A CA  1 
ATOM   535  C C   . ALA A 1 132 ? 128.560 116.817 98.010  1.00 49.61  ? 113 ALA A C   1 
ATOM   536  O O   . ALA A 1 132 ? 129.279 117.476 97.252  1.00 49.61  ? 113 ALA A O   1 
ATOM   537  C CB  . ALA A 1 132 ? 129.463 116.342 100.298 1.00 49.61  ? 113 ALA A CB  1 
ATOM   538  N N   . TYR A 1 133 ? 127.829 115.788 97.579  1.00 51.95  ? 114 TYR A N   1 
ATOM   539  C CA  . TYR A 1 133 ? 127.881 115.392 96.176  1.00 51.95  ? 114 TYR A CA  1 
ATOM   540  C C   . TYR A 1 133 ? 127.215 116.446 95.305  1.00 51.95  ? 114 TYR A C   1 
ATOM   541  O O   . TYR A 1 133 ? 127.708 116.776 94.221  1.00 51.95  ? 114 TYR A O   1 
ATOM   542  C CB  . TYR A 1 133 ? 127.204 114.037 95.976  1.00 51.95  ? 114 TYR A CB  1 
ATOM   543  C CG  . TYR A 1 133 ? 127.747 112.929 96.841  1.00 51.95  ? 114 TYR A CG  1 
ATOM   544  C CD1 . TYR A 1 133 ? 128.894 113.102 97.596  1.00 51.95  ? 114 TYR A CD1 1 
ATOM   545  C CD2 . TYR A 1 133 ? 127.111 111.706 96.898  1.00 51.95  ? 114 TYR A CD2 1 
ATOM   546  C CE1 . TYR A 1 133 ? 129.379 112.099 98.390  1.00 51.95  ? 114 TYR A CE1 1 
ATOM   547  C CE2 . TYR A 1 133 ? 127.596 110.692 97.683  1.00 51.95  ? 114 TYR A CE2 1 
ATOM   548  C CZ  . TYR A 1 133 ? 128.729 110.895 98.430  1.00 51.95  ? 114 TYR A CZ  1 
ATOM   549  O OH  . TYR A 1 133 ? 129.221 109.895 99.224  1.00 51.95  ? 114 TYR A OH  1 
ATOM   550  N N   . ILE A 1 134 ? 126.082 116.978 95.765  1.00 50.55  ? 115 ILE A N   1 
ATOM   551  C CA  . ILE A 1 134 ? 125.515 118.174 95.156  1.00 50.55  ? 115 ILE A CA  1 
ATOM   552  C C   . ILE A 1 134 ? 126.489 119.334 95.279  1.00 50.55  ? 115 ILE A C   1 
ATOM   553  O O   . ILE A 1 134 ? 126.659 120.120 94.343  1.00 50.55  ? 115 ILE A O   1 
ATOM   554  C CB  . ILE A 1 134 ? 124.159 118.509 95.800  1.00 50.55  ? 115 ILE A CB  1 
ATOM   555  C CG1 . ILE A 1 134 ? 123.113 117.467 95.430  1.00 50.55  ? 115 ILE A CG1 1 
ATOM   556  C CG2 . ILE A 1 134 ? 123.685 119.867 95.361  1.00 50.55  ? 115 ILE A CG2 1 
ATOM   557  C CD1 . ILE A 1 134 ? 121.719 117.860 95.836  1.00 50.55  ? 115 ILE A CD1 1 
ATOM   558  N N   . LEU A 1 135 ? 127.143 119.464 96.435  1.00 54.28  ? 116 LEU A N   1 
ATOM   559  C CA  . LEU A 1 135 ? 128.048 120.589 96.649  1.00 54.28  ? 116 LEU A CA  1 
ATOM   560  C C   . LEU A 1 135 ? 129.161 120.600 95.613  1.00 54.28  ? 116 LEU A C   1 
ATOM   561  O O   . LEU A 1 135 ? 129.308 121.563 94.852  1.00 54.28  ? 116 LEU A O   1 
ATOM   562  C CB  . LEU A 1 135 ? 128.631 120.536 98.058  1.00 54.28  ? 116 LEU A CB  1 
ATOM   563  C CG  . LEU A 1 135 ? 129.451 121.744 98.499  1.00 54.28  ? 116 LEU A CG  1 
ATOM   564  C CD1 . LEU A 1 135 ? 128.805 123.031 98.031  1.00 54.28  ? 116 LEU A CD1 1 
ATOM   565  C CD2 . LEU A 1 135 ? 129.611 121.743 100.003 1.00 54.28  ? 116 LEU A CD2 1 
ATOM   566  N N   . GLU A 1 136 ? 129.957 119.538 95.568  1.00 60.24  ? 117 GLU A N   1 
ATOM   567  C CA  . GLU A 1 136 ? 131.012 119.444 94.571  1.00 60.24  ? 117 GLU A CA  1 
ATOM   568  C C   . GLU A 1 136 ? 130.416 119.300 93.180  1.00 60.24  ? 117 GLU A C   1 
ATOM   569  O O   . GLU A 1 136 ? 129.460 118.545 92.979  1.00 60.24  ? 117 GLU A O   1 
ATOM   570  C CB  . GLU A 1 136 ? 131.927 118.262 94.886  1.00 60.24  ? 117 GLU A CB  1 
ATOM   571  C CG  . GLU A 1 136 ? 132.425 118.235 96.319  1.00 60.24  ? 117 GLU A CG  1 
ATOM   572  C CD  . GLU A 1 136 ? 133.426 119.334 96.613  1.00 60.24  ? 117 GLU A CD  1 
ATOM   573  O OE1 . GLU A 1 136 ? 134.107 119.787 95.669  1.00 60.24  ? 117 GLU A OE1 1 
ATOM   574  O OE2 . GLU A 1 136 ? 133.535 119.743 97.788  1.00 60.24  ? 117 GLU A OE2 1 
ATOM   575  N N   . ALA A 1 137 ? 130.975 120.053 92.233  1.00 71.31  ? 118 ALA A N   1 
ATOM   576  C CA  . ALA A 1 137 ? 130.651 120.056 90.808  1.00 71.31  ? 118 ALA A CA  1 
ATOM   577  C C   . ALA A 1 137 ? 129.347 120.766 90.468  1.00 71.31  ? 118 ALA A C   1 
ATOM   578  O O   . ALA A 1 137 ? 129.065 120.969 89.280  1.00 71.31  ? 118 ALA A O   1 
ATOM   579  C CB  . ALA A 1 137 ? 130.607 118.641 90.222  1.00 71.31  ? 118 ALA A CB  1 
ATOM   580  N N   . PHE A 1 138 ? 128.555 121.179 91.458  1.00 62.87  ? 119 PHE A N   1 
ATOM   581  C CA  . PHE A 1 138 ? 127.341 121.947 91.202  1.00 62.87  ? 119 PHE A CA  1 
ATOM   582  C C   . PHE A 1 138 ? 127.353 123.299 91.893  1.00 62.87  ? 119 PHE A C   1 
ATOM   583  O O   . PHE A 1 138 ? 126.752 124.252 91.386  1.00 62.87  ? 119 PHE A O   1 
ATOM   584  C CB  . PHE A 1 138 ? 126.093 121.167 91.637  1.00 62.87  ? 119 PHE A CB  1 
ATOM   585  C CG  . PHE A 1 138 ? 125.576 120.215 90.606  1.00 62.87  ? 119 PHE A CG  1 
ATOM   586  C CD1 . PHE A 1 138 ? 126.384 119.767 89.583  1.00 62.87  ? 119 PHE A CD1 1 
ATOM   587  C CD2 . PHE A 1 138 ? 124.275 119.768 90.663  1.00 62.87  ? 119 PHE A CD2 1 
ATOM   588  C CE1 . PHE A 1 138 ? 125.909 118.895 88.639  1.00 62.87  ? 119 PHE A CE1 1 
ATOM   589  C CE2 . PHE A 1 138 ? 123.795 118.895 89.723  1.00 62.87  ? 119 PHE A CE2 1 
ATOM   590  C CZ  . PHE A 1 138 ? 124.612 118.457 88.709  1.00 62.87  ? 119 PHE A CZ  1 
ATOM   591  N N   . GLY A 1 139 ? 128.010 123.411 93.031  1.00 61.99  ? 120 GLY A N   1 
ATOM   592  C CA  . GLY A 1 139 ? 128.188 124.688 93.695  1.00 61.99  ? 120 GLY A CA  1 
ATOM   593  C C   . GLY A 1 139 ? 127.390 124.788 94.980  1.00 61.99  ? 120 GLY A C   1 
ATOM   594  O O   . GLY A 1 139 ? 126.737 123.844 95.423  1.00 61.99  ? 120 GLY A O   1 
ATOM   595  N N   . GLY A 1 140 ? 127.449 125.972 95.592  1.00 67.32  ? 121 GLY A N   1 
ATOM   596  C CA  . GLY A 1 140 ? 126.852 126.155 96.904  1.00 67.32  ? 121 GLY A CA  1 
ATOM   597  C C   . GLY A 1 140 ? 125.336 126.170 96.884  1.00 67.32  ? 121 GLY A C   1 
ATOM   598  O O   . GLY A 1 140 ? 124.692 125.710 97.828  1.00 67.32  ? 121 GLY A O   1 
ATOM   599  N N   . PHE A 1 141 ? 124.747 126.723 95.822  1.00 66.17  ? 122 PHE A N   1 
ATOM   600  C CA  . PHE A 1 141 ? 123.320 127.035 95.825  1.00 66.17  ? 122 PHE A CA  1 
ATOM   601  C C   . PHE A 1 141 ? 122.470 125.789 96.049  1.00 66.17  ? 122 PHE A C   1 
ATOM   602  O O   . PHE A 1 141 ? 121.732 125.690 97.039  1.00 66.17  ? 122 PHE A O   1 
ATOM   603  C CB  . PHE A 1 141 ? 122.943 127.717 94.510  1.00 66.17  ? 122 PHE A CB  1 
ATOM   604  C CG  . PHE A 1 141 ? 121.496 128.095 94.415  1.00 66.17  ? 122 PHE A CG  1 
ATOM   605  C CD1 . PHE A 1 141 ? 120.784 128.459 95.542  1.00 66.17  ? 122 PHE A CD1 1 
ATOM   606  C CD2 . PHE A 1 141 ? 120.847 128.085 93.193  1.00 66.17  ? 122 PHE A CD2 1 
ATOM   607  C CE1 . PHE A 1 141 ? 119.454 128.803 95.453  1.00 66.17  ? 122 PHE A CE1 1 
ATOM   608  C CE2 . PHE A 1 141 ? 119.516 128.429 93.097  1.00 66.17  ? 122 PHE A CE2 1 
ATOM   609  C CZ  . PHE A 1 141 ? 118.818 128.789 94.230  1.00 66.17  ? 122 PHE A CZ  1 
ATOM   610  N N   . ILE A 1 142 ? 122.551 124.825 95.134  1.00 57.90  ? 123 ILE A N   1 
ATOM   611  C CA  . ILE A 1 142 ? 121.675 123.663 95.235  1.00 57.90  ? 123 ILE A CA  1 
ATOM   612  C C   . ILE A 1 142 ? 122.065 122.811 96.437  1.00 57.90  ? 123 ILE A C   1 
ATOM   613  O O   . ILE A 1 142 ? 121.228 122.118 97.031  1.00 57.90  ? 123 ILE A O   1 
ATOM   614  C CB  . ILE A 1 142 ? 121.705 122.862 93.925  1.00 57.90  ? 123 ILE A CB  1 
ATOM   615  C CG1 . ILE A 1 142 ? 121.329 123.764 92.758  1.00 57.90  ? 123 ILE A CG1 1 
ATOM   616  C CG2 . ILE A 1 142 ? 120.711 121.745 93.991  1.00 57.90  ? 123 ILE A CG2 1 
ATOM   617  C CD1 . ILE A 1 142 ? 121.589 123.144 91.415  1.00 57.90  ? 123 ILE A CD1 1 
ATOM   618  N N   . ALA A 1 143 ? 123.336 122.867 96.831  1.00 51.07  ? 124 ALA A N   1 
ATOM   619  C CA  . ALA A 1 143 ? 123.744 122.206 98.062  1.00 51.07  ? 124 ALA A CA  1 
ATOM   620  C C   . ALA A 1 143 ? 122.959 122.738 99.247  1.00 51.07  ? 124 ALA A C   1 
ATOM   621  O O   . ALA A 1 143 ? 122.374 121.964 100.016 1.00 51.07  ? 124 ALA A O   1 
ATOM   622  C CB  . ALA A 1 143 ? 125.240 122.390 98.286  1.00 51.07  ? 124 ALA A CB  1 
ATOM   623  N N   . PHE A 1 144 ? 122.927 124.059 99.408  1.00 55.65  ? 125 PHE A N   1 
ATOM   624  C CA  . PHE A 1 144 ? 122.190 124.641 100.519 1.00 55.65  ? 125 PHE A CA  1 
ATOM   625  C C   . PHE A 1 144 ? 120.700 124.385 100.377 1.00 55.65  ? 125 PHE A C   1 
ATOM   626  O O   . PHE A 1 144 ? 119.977 124.314 101.371 1.00 55.65  ? 125 PHE A O   1 
ATOM   627  C CB  . PHE A 1 144 ? 122.446 126.139 100.624 1.00 55.65  ? 125 PHE A CB  1 
ATOM   628  C CG  . PHE A 1 144 ? 121.580 126.813 101.641 1.00 55.65  ? 125 PHE A CG  1 
ATOM   629  C CD1 . PHE A 1 144 ? 121.721 126.522 102.982 1.00 55.65  ? 125 PHE A CD1 1 
ATOM   630  C CD2 . PHE A 1 144 ? 120.598 127.699 101.256 1.00 55.65  ? 125 PHE A CD2 1 
ATOM   631  C CE1 . PHE A 1 144 ? 120.924 127.127 103.918 1.00 55.65  ? 125 PHE A CE1 1 
ATOM   632  C CE2 . PHE A 1 144 ? 119.799 128.307 102.189 1.00 55.65  ? 125 PHE A CE2 1 
ATOM   633  C CZ  . PHE A 1 144 ? 119.961 128.020 103.521 1.00 55.65  ? 125 PHE A CZ  1 
ATOM   634  N N   . ILE A 1 145 ? 120.215 124.250 99.143  1.00 49.87  ? 126 ILE A N   1 
ATOM   635  C CA  . ILE A 1 145 ? 118.796 123.943 98.971  1.00 49.87  ? 126 ILE A CA  1 
ATOM   636  C C   . ILE A 1 145 ? 118.486 122.554 99.513  1.00 49.87  ? 126 ILE A C   1 
ATOM   637  O O   . ILE A 1 145 ? 117.479 122.345 100.208 1.00 49.87  ? 126 ILE A O   1 
ATOM   638  C CB  . ILE A 1 145 ? 118.389 124.084 97.497  1.00 49.87  ? 126 ILE A CB  1 
ATOM   639  C CG1 . ILE A 1 145 ? 118.419 125.553 97.105  1.00 49.87  ? 126 ILE A CG1 1 
ATOM   640  C CG2 . ILE A 1 145 ? 117.000 123.547 97.288  1.00 49.87  ? 126 ILE A CG2 1 
ATOM   641  C CD1 . ILE A 1 145 ? 117.754 126.435 98.116  1.00 49.87  ? 126 ILE A CD1 1 
ATOM   642  N N   . ARG A 1 146 ? 119.356 121.585 99.222  1.00 43.97  ? 127 ARG A N   1 
ATOM   643  C CA  . ARG A 1 146 ? 119.187 120.256 99.799  1.00 43.97  ? 127 ARG A CA  1 
ATOM   644  C C   . ARG A 1 146 ? 119.252 120.314 101.314 1.00 43.97  ? 127 ARG A C   1 
ATOM   645  O O   . ARG A 1 146 ? 118.439 119.693 102.007 1.00 43.97  ? 127 ARG A O   1 
ATOM   646  C CB  . ARG A 1 146 ? 120.251 119.296 99.278  1.00 43.97  ? 127 ARG A CB  1 
ATOM   647  C CG  . ARG A 1 146 ? 119.939 117.846 99.594  1.00 43.97  ? 127 ARG A CG  1 
ATOM   648  C CD  . ARG A 1 146 ? 120.560 117.397 100.901 1.00 43.97  ? 127 ARG A CD  1 
ATOM   649  N NE  . ARG A 1 146 ? 120.397 115.965 101.109 1.00 43.97  ? 127 ARG A NE  1 
ATOM   650  C CZ  . ARG A 1 146 ? 119.260 115.382 101.470 1.00 43.97  ? 127 ARG A CZ  1 
ATOM   651  N NH1 . ARG A 1 146 ? 118.172 116.108 101.666 1.00 43.97  ? 127 ARG A NH1 1 
ATOM   652  N NH2 . ARG A 1 146 ? 119.209 114.068 101.631 1.00 43.97  ? 127 ARG A NH2 1 
ATOM   653  N N   . LEU A 1 147 ? 120.233 121.041 101.847 1.00 44.24  ? 128 LEU A N   1 
ATOM   654  C CA  . LEU A 1 147 ? 120.373 121.115 103.296 1.00 44.24  ? 128 LEU A CA  1 
ATOM   655  C C   . LEU A 1 147 ? 119.150 121.755 103.933 1.00 44.24  ? 128 LEU A C   1 
ATOM   656  O O   . LEU A 1 147 ? 118.700 121.329 105.001 1.00 44.24  ? 128 LEU A O   1 
ATOM   657  C CB  . LEU A 1 147 ? 121.627 121.891 103.668 1.00 44.24  ? 128 LEU A CB  1 
ATOM   658  C CG  . LEU A 1 147 ? 121.885 121.891 105.164 1.00 44.24  ? 128 LEU A CG  1 
ATOM   659  C CD1 . LEU A 1 147 ? 121.908 120.474 105.682 1.00 44.24  ? 128 LEU A CD1 1 
ATOM   660  C CD2 . LEU A 1 147 ? 123.182 122.591 105.442 1.00 44.24  ? 128 LEU A CD2 1 
ATOM   661  N N   . TRP A 1 148 ? 118.577 122.759 103.276 1.00 50.00  ? 129 TRP A N   1 
ATOM   662  C CA  . TRP A 1 148 ? 117.383 123.399 103.804 1.00 50.00  ? 129 TRP A CA  1 
ATOM   663  C C   . TRP A 1 148 ? 116.208 122.440 103.825 1.00 50.00  ? 129 TRP A C   1 
ATOM   664  O O   . TRP A 1 148 ? 115.529 122.309 104.850 1.00 50.00  ? 129 TRP A O   1 
ATOM   665  C CB  . TRP A 1 148 ? 117.039 124.634 102.983 1.00 50.00  ? 129 TRP A CB  1 
ATOM   666  C CG  . TRP A 1 148 ? 116.127 125.550 103.693 1.00 50.00  ? 129 TRP A CG  1 
ATOM   667  C CD1 . TRP A 1 148 ? 114.836 125.821 103.374 1.00 50.00  ? 129 TRP A CD1 1 
ATOM   668  C CD2 . TRP A 1 148 ? 116.426 126.318 104.858 1.00 50.00  ? 129 TRP A CD2 1 
ATOM   669  N NE1 . TRP A 1 148 ? 114.309 126.722 104.264 1.00 50.00  ? 129 TRP A NE1 1 
ATOM   670  C CE2 . TRP A 1 148 ? 115.267 127.040 105.189 1.00 50.00  ? 129 TRP A CE2 1 
ATOM   671  C CE3 . TRP A 1 148 ? 117.564 126.469 105.654 1.00 50.00  ? 129 TRP A CE3 1 
ATOM   672  C CZ2 . TRP A 1 148 ? 115.210 127.899 106.278 1.00 50.00  ? 129 TRP A CZ2 1 
ATOM   673  C CZ3 . TRP A 1 148 ? 117.506 127.322 106.735 1.00 50.00  ? 129 TRP A CZ3 1 
ATOM   674  C CH2 . TRP A 1 148 ? 116.338 128.026 107.038 1.00 50.00  ? 129 TRP A CH2 1 
ATOM   675  N N   . VAL A 1 149 ? 115.943 121.759 102.708 1.00 44.69  ? 130 VAL A N   1 
ATOM   676  C CA  . VAL A 1 149 ? 114.765 120.901 102.708 1.00 44.69  ? 130 VAL A CA  1 
ATOM   677  C C   . VAL A 1 149 ? 114.985 119.696 103.610 1.00 44.69  ? 130 VAL A C   1 
ATOM   678  O O   . VAL A 1 149 ? 114.021 119.083 104.075 1.00 44.69  ? 130 VAL A O   1 
ATOM   679  C CB  . VAL A 1 149 ? 114.391 120.453 101.288 1.00 44.69  ? 130 VAL A CB  1 
ATOM   680  C CG1 . VAL A 1 149 ? 115.329 119.374 100.832 1.00 44.69  ? 130 VAL A CG1 1 
ATOM   681  C CG2 . VAL A 1 149 ? 112.959 119.966 101.250 1.00 44.69  ? 130 VAL A CG2 1 
ATOM   682  N N   . SER A 1 150 ? 116.239 119.351 103.906 1.00 42.97  ? 131 SER A N   1 
ATOM   683  C CA  . SER A 1 150 ? 116.484 118.271 104.851 1.00 42.97  ? 131 SER A CA  1 
ATOM   684  C C   . SER A 1 150 ? 116.588 118.762 106.281 1.00 42.97  ? 131 SER A C   1 
ATOM   685  O O   . SER A 1 150 ? 116.715 117.941 107.193 1.00 42.97  ? 131 SER A O   1 
ATOM   686  C CB  . SER A 1 150 ? 117.760 117.519 104.489 1.00 42.97  ? 131 SER A CB  1 
ATOM   687  O OG  . SER A 1 150 ? 118.103 116.615 105.519 1.00 42.97  ? 131 SER A OG  1 
ATOM   688  N N   . LEU A 1 151 ? 116.561 120.071 106.490 1.00 38.16  ? 132 LEU A N   1 
ATOM   689  C CA  . LEU A 1 151 ? 116.468 120.625 107.830 1.00 38.16  ? 132 LEU A CA  1 
ATOM   690  C C   . LEU A 1 151 ? 115.040 120.979 108.209 1.00 38.16  ? 132 LEU A C   1 
ATOM   691  O O   . LEU A 1 151 ? 114.711 120.995 109.398 1.00 38.16  ? 132 LEU A O   1 
ATOM   692  C CB  . LEU A 1 151 ? 117.355 121.866 107.941 1.00 38.16  ? 132 LEU A CB  1 
ATOM   693  C CG  . LEU A 1 151 ? 117.534 122.545 109.292 1.00 38.16  ? 132 LEU A CG  1 
ATOM   694  C CD1 . LEU A 1 151 ? 118.929 123.099 109.376 1.00 38.16  ? 132 LEU A CD1 1 
ATOM   695  C CD2 . LEU A 1 151 ? 116.530 123.663 109.471 1.00 38.16  ? 132 LEU A CD2 1 
ATOM   696  N N   . LEU A 1 152 ? 114.182 121.262 107.230 1.00 40.05  ? 133 LEU A N   1 
ATOM   697  C CA  . LEU A 1 152 ? 112.819 121.693 107.519 1.00 40.05  ? 133 LEU A CA  1 
ATOM   698  C C   . LEU A 1 152 ? 111.818 120.542 107.527 1.00 40.05  ? 133 LEU A C   1 
ATOM   699  O O   . LEU A 1 152 ? 111.170 120.293 108.546 1.00 40.05  ? 133 LEU A O   1 
ATOM   700  C CB  . LEU A 1 152 ? 112.371 122.755 106.513 1.00 40.05  ? 133 LEU A CB  1 
ATOM   701  C CG  . LEU A 1 152 ? 112.868 124.176 106.744 1.00 40.05  ? 133 LEU A CG  1 
ATOM   702  C CD1 . LEU A 1 152 ? 112.085 125.132 105.877 1.00 40.05  ? 133 LEU A CD1 1 
ATOM   703  C CD2 . LEU A 1 152 ? 112.740 124.545 108.203 1.00 40.05  ? 133 LEU A CD2 1 
ATOM   704  N N   . VAL A 1 153 ? 111.662 119.842 106.402 1.00 44.55  ? 134 VAL A N   1 
ATOM   705  C CA  . VAL A 1 153 ? 110.541 118.929 106.224 1.00 44.55  ? 134 VAL A CA  1 
ATOM   706  C C   . VAL A 1 153 ? 110.945 117.568 105.674 1.00 44.55  ? 134 VAL A C   1 
ATOM   707  O O   . VAL A 1 153 ? 110.092 116.847 105.159 1.00 44.55  ? 134 VAL A O   1 
ATOM   708  C CB  . VAL A 1 153 ? 109.457 119.579 105.335 1.00 44.55  ? 134 VAL A CB  1 
ATOM   709  C CG1 . VAL A 1 153 ? 109.841 119.534 103.860 1.00 44.55  ? 134 VAL A CG1 1 
ATOM   710  C CG2 . VAL A 1 153 ? 108.078 118.977 105.596 1.00 44.55  ? 134 VAL A CG2 1 
ATOM   711  N N   . VAL A 1 154 ? 112.206 117.161 105.796 1.00 46.85  ? 135 VAL A N   1 
ATOM   712  C CA  . VAL A 1 154 ? 112.561 115.811 105.367 1.00 46.85  ? 135 VAL A CA  1 
ATOM   713  C C   . VAL A 1 154 ? 113.098 115.007 106.542 1.00 46.85  ? 135 VAL A C   1 
ATOM   714  O O   . VAL A 1 154 ? 112.634 113.892 106.803 1.00 46.85  ? 135 VAL A O   1 
ATOM   715  C CB  . VAL A 1 154 ? 113.574 115.819 104.210 1.00 46.85  ? 135 VAL A CB  1 
ATOM   716  C CG1 . VAL A 1 154 ? 114.000 114.402 103.888 1.00 46.85  ? 135 VAL A CG1 1 
ATOM   717  C CG2 . VAL A 1 154 ? 112.964 116.444 102.984 1.00 46.85  ? 135 VAL A CG2 1 
ATOM   718  N N   . GLU A 1 155 ? 114.083 115.544 107.247 1.00 45.08  ? 136 GLU A N   1 
ATOM   719  C CA  . GLU A 1 155 ? 114.618 114.773 108.360 1.00 45.08  ? 136 GLU A CA  1 
ATOM   720  C C   . GLU A 1 155 ? 113.755 114.918 109.611 1.00 45.08  ? 136 GLU A C   1 
ATOM   721  O O   . GLU A 1 155 ? 113.477 113.908 110.271 1.00 45.08  ? 136 GLU A O   1 
ATOM   722  C CB  . GLU A 1 155 ? 116.071 115.153 108.647 1.00 45.08  ? 136 GLU A CB  1 
ATOM   723  C CG  . GLU A 1 155 ? 117.085 114.547 107.679 1.00 45.08  ? 136 GLU A CG  1 
ATOM   724  C CD  . GLU A 1 155 ? 116.974 113.036 107.528 1.00 45.08  ? 136 GLU A CD  1 
ATOM   725  O OE1 . GLU A 1 155 ? 117.530 112.499 106.549 1.00 45.08  ? 136 GLU A OE1 1 
ATOM   726  O OE2 . GLU A 1 155 ? 116.365 112.372 108.390 1.00 45.08  ? 136 GLU A OE2 1 
ATOM   727  N N   . PRO A 1 156 ? 113.310 116.125 109.983 1.00 39.98  ? 137 PRO A N   1 
ATOM   728  C CA  . PRO A 1 156 ? 112.379 116.211 111.120 1.00 39.98  ? 137 PRO A CA  1 
ATOM   729  C C   . PRO A 1 156 ? 111.108 115.410 110.915 1.00 39.98  ? 137 PRO A C   1 
ATOM   730  O O   . PRO A 1 156 ? 110.692 114.674 111.816 1.00 39.98  ? 137 PRO A O   1 
ATOM   731  C CB  . PRO A 1 156 ? 112.107 117.711 111.217 1.00 39.98  ? 137 PRO A CB  1 
ATOM   732  C CG  . PRO A 1 156 ? 113.363 118.314 110.775 1.00 39.98  ? 137 PRO A CG  1 
ATOM   733  C CD  . PRO A 1 156 ? 113.827 117.458 109.633 1.00 39.98  ? 137 PRO A CD  1 
ATOM   734  N N   . THR A 1 157 ? 110.487 115.510 109.742 1.00 40.94  ? 138 THR A N   1 
ATOM   735  C CA  . THR A 1 157 ? 109.272 114.742 109.499 1.00 40.94  ? 138 THR A CA  1 
ATOM   736  C C   . THR A 1 157 ? 109.563 113.249 109.453 1.00 40.94  ? 138 THR A C   1 
ATOM   737  O O   . THR A 1 157 ? 108.787 112.447 109.981 1.00 40.94  ? 138 THR A O   1 
ATOM   738  C CB  . THR A 1 157 ? 108.609 115.205 108.206 1.00 40.94  ? 138 THR A CB  1 
ATOM   739  O OG1 . THR A 1 157 ? 107.976 116.470 108.424 1.00 40.94  ? 138 THR A OG1 1 
ATOM   740  C CG2 . THR A 1 157 ? 107.570 114.212 107.753 1.00 40.94  ? 138 THR A CG2 1 
ATOM   741  N N   . GLY A 1 158 ? 110.680 112.856 108.839 1.00 39.30  ? 139 GLY A N   1 
ATOM   742  C CA  . GLY A 1 158 ? 111.042 111.446 108.815 1.00 39.30  ? 139 GLY A CA  1 
ATOM   743  C C   . GLY A 1 158 ? 111.173 110.854 110.205 1.00 39.30  ? 139 GLY A C   1 
ATOM   744  O O   . GLY A 1 158 ? 110.556 109.832 110.525 1.00 39.30  ? 139 GLY A O   1 
ATOM   745  N N   . GLN A 1 159 ? 111.970 111.498 111.061 1.00 32.30  ? 140 GLN A N   1 
ATOM   746  C CA  . GLN A 1 159 ? 112.151 110.972 112.407 1.00 32.30  ? 140 GLN A CA  1 
ATOM   747  C C   . GLN A 1 159 ? 110.864 111.051 113.217 1.00 32.30  ? 140 GLN A C   1 
ATOM   748  O O   . GLN A 1 159 ? 110.567 110.143 113.999 1.00 32.30  ? 140 GLN A O   1 
ATOM   749  C CB  . GLN A 1 159 ? 113.274 111.709 113.125 1.00 32.30  ? 140 GLN A CB  1 
ATOM   750  C CG  . GLN A 1 159 ? 114.551 111.791 112.347 1.00 32.30  ? 140 GLN A CG  1 
ATOM   751  C CD  . GLN A 1 159 ? 115.343 113.016 112.710 1.00 32.30  ? 140 GLN A CD  1 
ATOM   752  O OE1 . GLN A 1 159 ? 115.115 113.626 113.750 1.00 32.30  ? 140 GLN A OE1 1 
ATOM   753  N NE2 . GLN A 1 159 ? 116.279 113.389 111.855 1.00 32.30  ? 140 GLN A NE2 1 
ATOM   754  N N   . ALA A 1 160 ? 110.076 112.115 113.043 1.00 34.88  ? 141 ALA A N   1 
ATOM   755  C CA  . ALA A 1 160 ? 108.845 112.229 113.812 1.00 34.88  ? 141 ALA A CA  1 
ATOM   756  C C   . ALA A 1 160 ? 107.860 111.135 113.434 1.00 34.88  ? 141 ALA A C   1 
ATOM   757  O O   . ALA A 1 160 ? 107.205 110.555 114.305 1.00 34.88  ? 141 ALA A O   1 
ATOM   758  C CB  . ALA A 1 160 ? 108.220 113.605 113.610 1.00 34.88  ? 141 ALA A CB  1 
ATOM   759  N N   . ILE A 1 161 ? 107.765 110.809 112.145 1.00 36.62  ? 142 ILE A N   1 
ATOM   760  C CA  . ILE A 1 161 ? 106.843 109.761 111.722 1.00 36.62  ? 142 ILE A CA  1 
ATOM   761  C C   . ILE A 1 161 ? 107.334 108.395 112.177 1.00 36.62  ? 142 ILE A C   1 
ATOM   762  O O   . ILE A 1 161 ? 106.538 107.547 112.598 1.00 36.62  ? 142 ILE A O   1 
ATOM   763  C CB  . ILE A 1 161 ? 106.636 109.808 110.202 1.00 36.62  ? 142 ILE A CB  1 
ATOM   764  C CG1 . ILE A 1 161 ? 105.870 111.066 109.823 1.00 36.62  ? 142 ILE A CG1 1 
ATOM   765  C CG2 . ILE A 1 161 ? 105.884 108.587 109.737 1.00 36.62  ? 142 ILE A CG2 1 
ATOM   766  C CD1 . ILE A 1 161 ? 105.723 111.239 108.355 1.00 36.62  ? 142 ILE A CD1 1 
ATOM   767  N N   . ILE A 1 162 ? 108.645 108.154 112.114 1.00 32.36  ? 143 ILE A N   1 
ATOM   768  C CA  . ILE A 1 162 ? 109.145 106.857 112.561 1.00 32.36  ? 143 ILE A CA  1 
ATOM   769  C C   . ILE A 1 162 ? 108.934 106.691 114.061 1.00 32.36  ? 143 ILE A C   1 
ATOM   770  O O   . ILE A 1 162 ? 108.545 105.615 114.532 1.00 32.36  ? 143 ILE A O   1 
ATOM   771  C CB  . ILE A 1 162 ? 110.618 106.678 112.168 1.00 32.36  ? 143 ILE A CB  1 
ATOM   772  C CG1 . ILE A 1 162 ? 110.758 106.687 110.649 1.00 32.36  ? 143 ILE A CG1 1 
ATOM   773  C CG2 . ILE A 1 162 ? 111.139 105.377 112.709 1.00 32.36  ? 143 ILE A CG2 1 
ATOM   774  C CD1 . ILE A 1 162 ? 112.121 106.262 110.165 1.00 32.36  ? 143 ILE A CD1 1 
ATOM   775  N N   . ALA A 1 163 ? 109.143 107.755 114.836 1.00 32.86  ? 144 ALA A N   1 
ATOM   776  C CA  . ALA A 1 163 ? 108.903 107.656 116.270 1.00 32.86  ? 144 ALA A CA  1 
ATOM   777  C C   . ALA A 1 163 ? 107.420 107.513 116.587 1.00 32.86  ? 144 ALA A C   1 
ATOM   778  O O   . ALA A 1 163 ? 107.056 106.805 117.533 1.00 32.86  ? 144 ALA A O   1 
ATOM   779  C CB  . ALA A 1 163 ? 109.481 108.868 116.990 1.00 32.86  ? 144 ALA A CB  1 
ATOM   780  N N   . ILE A 1 164 ? 106.547 108.164 115.816 1.00 34.17  ? 145 ILE A N   1 
ATOM   781  C CA  . ILE A 1 164 ? 105.117 108.010 116.050 1.00 34.17  ? 145 ILE A CA  1 
ATOM   782  C C   . ILE A 1 164 ? 104.678 106.587 115.739 1.00 34.17  ? 145 ILE A C   1 
ATOM   783  O O   . ILE A 1 164 ? 103.841 106.017 116.444 1.00 34.17  ? 145 ILE A O   1 
ATOM   784  C CB  . ILE A 1 164 ? 104.324 109.035 115.226 1.00 34.17  ? 145 ILE A CB  1 
ATOM   785  C CG1 . ILE A 1 164 ? 104.371 110.404 115.884 1.00 34.17  ? 145 ILE A CG1 1 
ATOM   786  C CG2 . ILE A 1 164 ? 102.888 108.616 115.117 1.00 34.17  ? 145 ILE A CG2 1 
ATOM   787  C CD1 . ILE A 1 164 ? 103.588 111.444 115.132 1.00 34.17  ? 145 ILE A CD1 1 
ATOM   788  N N   . THR A 1 165 ? 105.233 105.986 114.685 1.00 34.32  ? 146 THR A N   1 
ATOM   789  C CA  . THR A 1 165 ? 104.904 104.594 114.397 1.00 34.32  ? 146 THR A CA  1 
ATOM   790  C C   . THR A 1 165 ? 105.447 103.666 115.475 1.00 34.32  ? 146 THR A C   1 
ATOM   791  O O   . THR A 1 165 ? 104.797 102.674 115.825 1.00 34.32  ? 146 THR A O   1 
ATOM   792  C CB  . THR A 1 165 ? 105.442 104.189 113.029 1.00 34.32  ? 146 THR A CB  1 
ATOM   793  O OG1 . THR A 1 165 ? 104.898 105.058 112.030 1.00 34.32  ? 146 THR A OG1 1 
ATOM   794  C CG2 . THR A 1 165 ? 105.029 102.773 112.703 1.00 34.32  ? 146 THR A CG2 1 
ATOM   795  N N   . PHE A 1 166 ? 106.621 103.980 116.023 1.00 32.85  ? 147 PHE A N   1 
ATOM   796  C CA  . PHE A 1 166 ? 107.118 103.241 117.178 1.00 32.85  ? 147 PHE A CA  1 
ATOM   797  C C   . PHE A 1 166 ? 106.123 103.293 118.326 1.00 32.85  ? 147 PHE A C   1 
ATOM   798  O O   . PHE A 1 166 ? 105.795 102.265 118.926 1.00 32.85  ? 147 PHE A O   1 
ATOM   799  C CB  . PHE A 1 166 ? 108.463 103.805 117.621 1.00 32.85  ? 147 PHE A CB  1 
ATOM   800  C CG  . PHE A 1 166 ? 108.914 103.305 118.956 1.00 32.85  ? 147 PHE A CG  1 
ATOM   801  C CD1 . PHE A 1 166 ? 109.094 101.956 119.178 1.00 32.85  ? 147 PHE A CD1 1 
ATOM   802  C CD2 . PHE A 1 166 ? 109.158 104.185 119.987 1.00 32.85  ? 147 PHE A CD2 1 
ATOM   803  C CE1 . PHE A 1 166 ? 109.513 101.495 120.406 1.00 32.85  ? 147 PHE A CE1 1 
ATOM   804  C CE2 . PHE A 1 166 ? 109.574 103.728 121.215 1.00 32.85  ? 147 PHE A CE2 1 
ATOM   805  C CZ  . PHE A 1 166 ? 109.752 102.382 121.425 1.00 32.85  ? 147 PHE A CZ  1 
ATOM   806  N N   . ALA A 1 167 ? 105.635 104.489 118.649 1.00 37.92  ? 148 ALA A N   1 
ATOM   807  C CA  . ALA A 1 167 ? 104.661 104.617 119.729 1.00 37.92  ? 148 ALA A CA  1 
ATOM   808  C C   . ALA A 1 167 ? 103.387 103.844 119.420 1.00 37.92  ? 148 ALA A C   1 
ATOM   809  O O   . ALA A 1 167 ? 102.838 103.166 120.294 1.00 37.92  ? 148 ALA A O   1 
ATOM   810  C CB  . ALA A 1 167 ? 104.342 106.087 119.986 1.00 37.92  ? 148 ALA A CB  1 
ATOM   811  N N   . ASN A 1 168 ? 102.898 103.943 118.184 1.00 39.27  ? 149 ASN A N   1 
ATOM   812  C CA  . ASN A 1 168 ? 101.658 103.269 117.812 1.00 39.27  ? 149 ASN A CA  1 
ATOM   813  C C   . ASN A 1 168 ? 101.783 101.758 117.927 1.00 39.27  ? 149 ASN A C   1 
ATOM   814  O O   . ASN A 1 168 ? 100.835 101.084 118.343 1.00 39.27  ? 149 ASN A O   1 
ATOM   815  C CB  . ASN A 1 168 ? 101.257 103.649 116.390 1.00 39.27  ? 149 ASN A CB  1 
ATOM   816  C CG  . ASN A 1 168 ? 100.564 104.982 116.320 1.00 39.27  ? 149 ASN A CG  1 
ATOM   817  O OD1 . ASN A 1 168 ? 100.083 105.491 117.325 1.00 39.27  ? 149 ASN A OD1 1 
ATOM   818  N ND2 . ASN A 1 168 ? 100.508 105.560 115.128 1.00 39.27  ? 149 ASN A ND2 1 
ATOM   819  N N   . TYR A 1 169 ? 102.934 101.202 117.562 1.00 43.90  ? 150 TYR A N   1 
ATOM   820  C CA  . TYR A 1 169 ? 103.075 99.756  117.509 1.00 43.90  ? 150 TYR A CA  1 
ATOM   821  C C   . TYR A 1 169 ? 103.802 99.175  118.709 1.00 43.90  ? 150 TYR A C   1 
ATOM   822  O O   . TYR A 1 169 ? 104.061 97.970  118.729 1.00 43.90  ? 150 TYR A O   1 
ATOM   823  C CB  . TYR A 1 169 ? 103.783 99.342  116.222 1.00 43.90  ? 150 TYR A CB  1 
ATOM   824  C CG  . TYR A 1 169 ? 102.869 99.367  115.027 1.00 43.90  ? 150 TYR A CG  1 
ATOM   825  C CD1 . TYR A 1 169 ? 102.325 100.557 114.577 1.00 43.90  ? 150 TYR A CD1 1 
ATOM   826  C CD2 . TYR A 1 169 ? 102.542 98.203  114.354 1.00 43.90  ? 150 TYR A CD2 1 
ATOM   827  C CE1 . TYR A 1 169 ? 101.486 100.591 113.491 1.00 43.90  ? 150 TYR A CE1 1 
ATOM   828  C CE2 . TYR A 1 169 ? 101.700 98.226  113.266 1.00 43.90  ? 150 TYR A CE2 1 
ATOM   829  C CZ  . TYR A 1 169 ? 101.175 99.425  112.840 1.00 43.90  ? 150 TYR A CZ  1 
ATOM   830  O OH  . TYR A 1 169 ? 100.335 99.463  111.755 1.00 43.90  ? 150 TYR A OH  1 
ATOM   831  N N   . ILE A 1 170 ? 104.145 99.989  119.702 1.00 44.04  ? 151 ILE A N   1 
ATOM   832  C CA  . ILE A 1 170 ? 104.613 99.430  120.963 1.00 44.04  ? 151 ILE A CA  1 
ATOM   833  C C   . ILE A 1 170 ? 103.446 99.173  121.911 1.00 44.04  ? 151 ILE A C   1 
ATOM   834  O O   . ILE A 1 170 ? 103.490 98.225  122.700 1.00 44.04  ? 151 ILE A O   1 
ATOM   835  C CB  . ILE A 1 170 ? 105.672 100.341 121.610 1.00 44.04  ? 151 ILE A CB  1 
ATOM   836  C CG1 . ILE A 1 170 ? 106.304 99.669  122.828 1.00 44.04  ? 151 ILE A CG1 1 
ATOM   837  C CG2 . ILE A 1 170 ? 105.072 101.665 122.014 1.00 44.04  ? 151 ILE A CG2 1 
ATOM   838  C CD1 . ILE A 1 170 ? 107.148 98.473  122.501 1.00 44.04  ? 151 ILE A CD1 1 
ATOM   839  N N   . ILE A 1 171 ? 102.389 99.985  121.835 1.00 51.02  ? 152 ILE A N   1 
ATOM   840  C CA  . ILE A 1 171 ? 101.211 99.818  122.677 1.00 51.02  ? 152 ILE A CA  1 
ATOM   841  C C   . ILE A 1 171 ? 100.056 99.175  121.936 1.00 51.02  ? 152 ILE A C   1 
ATOM   842  O O   . ILE A 1 171 ? 98.978  99.003  122.519 1.00 51.02  ? 152 ILE A O   1 
ATOM   843  C CB  . ILE A 1 171 ? 100.761 101.163 123.276 1.00 51.02  ? 152 ILE A CB  1 
ATOM   844  C CG1 . ILE A 1 171 ? 100.125 102.035 122.198 1.00 51.02  ? 152 ILE A CG1 1 
ATOM   845  C CG2 . ILE A 1 171 ? 101.930 101.878 123.902 1.00 51.02  ? 152 ILE A CG2 1 
ATOM   846  C CD1 . ILE A 1 171 ? 99.762  103.411 122.678 1.00 51.02  ? 152 ILE A CD1 1 
ATOM   847  N N   . GLN A 1 172 ? 100.241 98.823  120.667 1.00 58.06  ? 153 GLN A N   1 
ATOM   848  C CA  . GLN A 1 172 ? 99.155  98.215  119.905 1.00 58.06  ? 153 GLN A CA  1 
ATOM   849  C C   . GLN A 1 172 ? 98.653  96.898  120.489 1.00 58.06  ? 153 GLN A C   1 
ATOM   850  O O   . GLN A 1 172 ? 97.432  96.672  120.443 1.00 58.06  ? 153 GLN A O   1 
ATOM   851  C CB  . GLN A 1 172 ? 99.593  98.033  118.449 1.00 58.06  ? 153 GLN A CB  1 
ATOM   852  C CG  . GLN A 1 172 ? 98.487  97.610  117.509 1.00 58.06  ? 153 GLN A CG  1 
ATOM   853  C CD  . GLN A 1 172 ? 98.405  96.112  117.356 1.00 58.06  ? 153 GLN A CD  1 
ATOM   854  O OE1 . GLN A 1 172 ? 99.193  95.373  117.943 1.00 58.06  ? 153 GLN A OE1 1 
ATOM   855  N NE2 . GLN A 1 172 ? 97.452  95.651  116.558 1.00 58.06  ? 153 GLN A NE2 1 
ATOM   856  N N   . PRO A 1 173 ? 99.486  96.002  121.032 1.00 57.67  ? 154 PRO A N   1 
ATOM   857  C CA  . PRO A 1 173 ? 98.926  94.787  121.646 1.00 57.67  ? 154 PRO A CA  1 
ATOM   858  C C   . PRO A 1 173 ? 98.017  95.063  122.828 1.00 57.67  ? 154 PRO A C   1 
ATOM   859  O O   . PRO A 1 173 ? 97.213  94.194  123.184 1.00 57.67  ? 154 PRO A O   1 
ATOM   860  C CB  . PRO A 1 173 ? 100.173 93.998  122.069 1.00 57.67  ? 154 PRO A CB  1 
ATOM   861  C CG  . PRO A 1 173 ? 101.252 95.001  122.135 1.00 57.67  ? 154 PRO A CG  1 
ATOM   862  C CD  . PRO A 1 173 ? 100.955 95.948  121.023 1.00 57.67  ? 154 PRO A CD  1 
ATOM   863  N N   . SER A 1 174 ? 98.116  96.236  123.453 1.00 67.02  ? 155 SER A N   1 
ATOM   864  C CA  . SER A 1 174 ? 97.160  96.633  124.476 1.00 67.02  ? 155 SER A CA  1 
ATOM   865  C C   . SER A 1 174 ? 95.917  97.294  123.899 1.00 67.02  ? 155 SER A C   1 
ATOM   866  O O   . SER A 1 174 ? 94.870  97.288  124.556 1.00 67.02  ? 155 SER A O   1 
ATOM   867  C CB  . SER A 1 174 ? 97.814  97.583  125.484 1.00 67.02  ? 155 SER A CB  1 
ATOM   868  O OG  . SER A 1 174 ? 98.829  96.928  126.221 1.00 67.02  ? 155 SER A OG  1 
ATOM   869  N N   . PHE A 1 175 ? 96.003  97.859  122.696 1.00 69.76  ? 156 PHE A N   1 
ATOM   870  C CA  . PHE A 1 175 ? 94.880  98.544  122.053 1.00 69.76  ? 156 PHE A CA  1 
ATOM   871  C C   . PHE A 1 175 ? 94.653  97.967  120.660 1.00 69.76  ? 156 PHE A C   1 
ATOM   872  O O   . PHE A 1 175 ? 94.869  98.643  119.651 1.00 69.76  ? 156 PHE A O   1 
ATOM   873  C CB  . PHE A 1 175 ? 95.136  100.048 121.975 1.00 69.76  ? 156 PHE A CB  1 
ATOM   874  C CG  . PHE A 1 175 ? 95.049  100.758 123.294 1.00 69.76  ? 156 PHE A CG  1 
ATOM   875  C CD1 . PHE A 1 175 ? 95.927  100.465 124.319 1.00 69.76  ? 156 PHE A CD1 1 
ATOM   876  C CD2 . PHE A 1 175 ? 94.110  101.748 123.494 1.00 69.76  ? 156 PHE A CD2 1 
ATOM   877  C CE1 . PHE A 1 175 ? 95.849  101.122 125.521 1.00 69.76  ? 156 PHE A CE1 1 
ATOM   878  C CE2 . PHE A 1 175 ? 94.029  102.409 124.695 1.00 69.76  ? 156 PHE A CE2 1 
ATOM   879  C CZ  . PHE A 1 175 ? 94.900  102.096 125.709 1.00 69.76  ? 156 PHE A CZ  1 
ATOM   880  N N   . PRO A 1 176 ? 94.221  96.709  120.567 1.00 76.22  ? 157 PRO A N   1 
ATOM   881  C CA  . PRO A 1 176 ? 94.130  96.057  119.253 1.00 76.22  ? 157 PRO A CA  1 
ATOM   882  C C   . PRO A 1 176 ? 93.160  96.710  118.281 1.00 76.22  ? 157 PRO A C   1 
ATOM   883  O O   . PRO A 1 176 ? 93.551  97.092  117.174 1.00 76.22  ? 157 PRO A O   1 
ATOM   884  C CB  . PRO A 1 176 ? 93.671  94.637  119.608 1.00 76.22  ? 157 PRO A CB  1 
ATOM   885  C CG  . PRO A 1 176 ? 94.112  94.442  121.013 1.00 76.22  ? 157 PRO A CG  1 
ATOM   886  C CD  . PRO A 1 176 ? 93.896  95.775  121.655 1.00 76.22  ? 157 PRO A CD  1 
ATOM   887  N N   . SER A 1 177 ? 91.897  96.847  118.678 1.00 90.12  ? 158 SER A N   1 
ATOM   888  C CA  . SER A 1 177 ? 90.813  97.112  117.741 1.00 90.12  ? 158 SER A CA  1 
ATOM   889  C C   . SER A 1 177 ? 90.432  98.584  117.634 1.00 90.12  ? 158 SER A C   1 
ATOM   890  O O   . SER A 1 177 ? 89.633  98.936  116.761 1.00 90.12  ? 158 SER A O   1 
ATOM   891  C CB  . SER A 1 177 ? 89.578  96.299  118.131 1.00 90.12  ? 158 SER A CB  1 
ATOM   892  O OG  . SER A 1 177 ? 88.825  96.973  119.123 1.00 90.12  ? 158 SER A OG  1 
ATOM   893  N N   . CYS A 1 178 ? 90.970  99.447  118.488 1.00 91.45  ? 159 CYS A N   1 
ATOM   894  C CA  . CYS A 1 178 ? 90.597  100.852 118.498 1.00 91.45  ? 159 CYS A CA  1 
ATOM   895  C C   . CYS A 1 178 ? 91.825  101.743 118.376 1.00 91.45  ? 159 CYS A C   1 
ATOM   896  O O   . CYS A 1 178 ? 92.936  101.273 118.120 1.00 91.45  ? 159 CYS A O   1 
ATOM   897  C CB  . CYS A 1 178 ? 89.821  101.203 119.768 1.00 91.45  ? 159 CYS A CB  1 
ATOM   898  S SG  . CYS A 1 178 ? 90.499  100.461 121.250 1.00 91.45  ? 159 CYS A SG  1 
ATOM   899  N N   . ASP A 1 179 ? 91.606  103.039 118.553 1.00 90.09  ? 160 ASP A N   1 
ATOM   900  C CA  . ASP A 1 179 ? 92.650  104.035 118.364 1.00 90.09  ? 160 ASP A CA  1 
ATOM   901  C C   . ASP A 1 179 ? 93.357  104.333 119.681 1.00 90.09  ? 160 ASP A C   1 
ATOM   902  O O   . ASP A 1 179 ? 92.717  104.783 120.641 1.00 90.09  ? 160 ASP A O   1 
ATOM   903  C CB  . ASP A 1 179 ? 92.061  105.320 117.777 1.00 90.09  ? 160 ASP A CB  1 
ATOM   904  C CG  . ASP A 1 179 ? 91.398  105.096 116.432 1.00 90.09  ? 160 ASP A CG  1 
ATOM   905  O OD1 . ASP A 1 179 ? 91.752  104.113 115.750 1.00 90.09  ? 160 ASP A OD1 1 
ATOM   906  O OD2 . ASP A 1 179 ? 90.523  105.903 116.056 1.00 90.09  ? 160 ASP A OD2 1 
ATOM   907  N N   . PRO A 1 180 ? 94.661  104.082 119.768 1.00 75.83  ? 161 PRO A N   1 
ATOM   908  C CA  . PRO A 1 180 ? 95.423  104.453 120.967 1.00 75.83  ? 161 PRO A CA  1 
ATOM   909  C C   . PRO A 1 180 ? 95.283  105.935 121.264 1.00 75.83  ? 161 PRO A C   1 
ATOM   910  O O   . PRO A 1 180 ? 95.083  106.743 120.344 1.00 75.83  ? 161 PRO A O   1 
ATOM   911  C CB  . PRO A 1 180 ? 96.869  104.098 120.592 1.00 75.83  ? 161 PRO A CB  1 
ATOM   912  C CG  . PRO A 1 180 ? 96.751  103.084 119.521 1.00 75.83  ? 161 PRO A CG  1 
ATOM   913  C CD  . PRO A 1 180 ? 95.485  103.370 118.777 1.00 75.83  ? 161 PRO A CD  1 
ATOM   914  N N   . PRO A 1 181 ? 95.381  106.335 122.533 1.00 60.45  ? 162 PRO A N   1 
ATOM   915  C CA  . PRO A 1 181 ? 95.212  107.753 122.867 1.00 60.45  ? 162 PRO A CA  1 
ATOM   916  C C   . PRO A 1 181 ? 96.347  108.604 122.323 1.00 60.45  ? 162 PRO A C   1 
ATOM   917  O O   . PRO A 1 181 ? 97.507  108.436 122.708 1.00 60.45  ? 162 PRO A O   1 
ATOM   918  C CB  . PRO A 1 181 ? 95.179  107.751 124.397 1.00 60.45  ? 162 PRO A CB  1 
ATOM   919  C CG  . PRO A 1 181 ? 95.967  106.559 124.783 1.00 60.45  ? 162 PRO A CG  1 
ATOM   920  C CD  . PRO A 1 181 ? 95.776  105.532 123.702 1.00 60.45  ? 162 PRO A CD  1 
ATOM   921  N N   . TYR A 1 182 ? 96.001  109.515 121.414 1.00 55.92  ? 163 TYR A N   1 
ATOM   922  C CA  . TYR A 1 182 ? 96.918  110.422 120.730 1.00 55.92  ? 163 TYR A CA  1 
ATOM   923  C C   . TYR A 1 182 ? 97.967  111.006 121.673 1.00 55.92  ? 163 TYR A C   1 
ATOM   924  O O   . TYR A 1 182 ? 99.141  111.136 121.305 1.00 55.92  ? 163 TYR A O   1 
ATOM   925  C CB  . TYR A 1 182 ? 96.089  111.519 120.060 1.00 55.92  ? 163 TYR A CB  1 
ATOM   926  C CG  . TYR A 1 182 ? 96.824  112.751 119.598 1.00 55.92  ? 163 TYR A CG  1 
ATOM   927  C CD1 . TYR A 1 182 ? 97.392  112.809 118.336 1.00 55.92  ? 163 TYR A CD1 1 
ATOM   928  C CD2 . TYR A 1 182 ? 96.905  113.875 120.403 1.00 55.92  ? 163 TYR A CD2 1 
ATOM   929  C CE1 . TYR A 1 182 ? 98.042  113.943 117.902 1.00 55.92  ? 163 TYR A CE1 1 
ATOM   930  C CE2 . TYR A 1 182 ? 97.556  115.012 119.977 1.00 55.92  ? 163 TYR A CE2 1 
ATOM   931  C CZ  . TYR A 1 182 ? 98.122  115.041 118.727 1.00 55.92  ? 163 TYR A CZ  1 
ATOM   932  O OH  . TYR A 1 182 ? 98.772  116.174 118.300 1.00 55.92  ? 163 TYR A OH  1 
ATOM   933  N N   . LEU A 1 183 ? 97.550  111.350 122.893 1.00 52.10  ? 164 LEU A N   1 
ATOM   934  C CA  . LEU A 1 183 ? 98.494  111.828 123.897 1.00 52.10  ? 164 LEU A CA  1 
ATOM   935  C C   . LEU A 1 183 ? 99.603  110.817 124.146 1.00 52.10  ? 164 LEU A C   1 
ATOM   936  O O   . LEU A 1 183 ? 100.782 111.181 124.197 1.00 52.10  ? 164 LEU A O   1 
ATOM   937  C CB  . LEU A 1 183 ? 97.764  112.130 125.203 1.00 52.10  ? 164 LEU A CB  1 
ATOM   938  C CG  . LEU A 1 183 ? 98.497  113.049 126.179 1.00 52.10  ? 164 LEU A CG  1 
ATOM   939  C CD1 . LEU A 1 183 ? 99.099  114.238 125.445 1.00 52.10  ? 164 LEU A CD1 1 
ATOM   940  C CD2 . LEU A 1 183 ? 97.571  113.507 127.298 1.00 52.10  ? 164 LEU A CD2 1 
ATOM   941  N N   . ALA A 1 184 ? 99.245  109.545 124.323 1.00 52.36  ? 165 ALA A N   1 
ATOM   942  C CA  . ALA A 1 184 ? 100.262 108.531 124.573 1.00 52.36  ? 165 ALA A CA  1 
ATOM   943  C C   . ALA A 1 184 ? 101.179 108.372 123.373 1.00 52.36  ? 165 ALA A C   1 
ATOM   944  O O   . ALA A 1 184 ? 102.400 108.270 123.529 1.00 52.36  ? 165 ALA A O   1 
ATOM   945  C CB  . ALA A 1 184 ? 99.608  107.197 124.925 1.00 52.36  ? 165 ALA A CB  1 
ATOM   946  N N   . CYS A 1 185 ? 100.607 108.339 122.169 1.00 52.57  ? 166 CYS A N   1 
ATOM   947  C CA  . CYS A 1 185 ? 101.413 108.295 120.954 1.00 52.57  ? 166 CYS A CA  1 
ATOM   948  C C   . CYS A 1 185 ? 102.480 109.379 120.969 1.00 52.57  ? 166 CYS A C   1 
ATOM   949  O O   . CYS A 1 185 ? 103.679 109.092 120.862 1.00 52.57  ? 166 CYS A O   1 
ATOM   950  C CB  . CYS A 1 185 ? 100.514 108.456 119.729 1.00 52.57  ? 166 CYS A CB  1 
ATOM   951  S SG  . CYS A 1 185 ? 99.173  107.262 119.616 1.00 52.57  ? 166 CYS A SG  1 
ATOM   952  N N   . ARG A 1 186 ? 102.061 110.636 121.124 1.00 45.32  ? 167 ARG A N   1 
ATOM   953  C CA  . ARG A 1 186 ? 103.009 111.738 121.022 1.00 45.32  ? 167 ARG A CA  1 
ATOM   954  C C   . ARG A 1 186 ? 104.022 111.723 122.159 1.00 45.32  ? 167 ARG A C   1 
ATOM   955  O O   . ARG A 1 186 ? 105.220 111.916 121.925 1.00 45.32  ? 167 ARG A O   1 
ATOM   956  C CB  . ARG A 1 186 ? 102.269 113.070 120.976 1.00 45.32  ? 167 ARG A CB  1 
ATOM   957  C CG  . ARG A 1 186 ? 101.498 113.276 119.695 1.00 45.32  ? 167 ARG A CG  1 
ATOM   958  C CD  . ARG A 1 186 ? 102.281 112.758 118.505 1.00 45.32  ? 167 ARG A CD  1 
ATOM   959  N NE  . ARG A 1 186 ? 101.408 112.323 117.421 1.00 45.32  ? 167 ARG A NE  1 
ATOM   960  C CZ  . ARG A 1 186 ? 100.899 113.133 116.501 1.00 45.32  ? 167 ARG A CZ  1 
ATOM   961  N NH1 . ARG A 1 186 ? 101.173 114.428 116.527 1.00 45.32  ? 167 ARG A NH1 1 
ATOM   962  N NH2 . ARG A 1 186 ? 100.113 112.646 115.552 1.00 45.32  ? 167 ARG A NH2 1 
ATOM   963  N N   . LEU A 1 187 ? 103.573 111.513 123.398 1.00 43.54  ? 168 LEU A N   1 
ATOM   964  C CA  . LEU A 1 187 ? 104.511 111.526 124.515 1.00 43.54  ? 168 LEU A CA  1 
ATOM   965  C C   . LEU A 1 187 ? 105.544 110.418 124.380 1.00 43.54  ? 168 LEU A C   1 
ATOM   966  O O   . LEU A 1 187 ? 106.741 110.642 124.582 1.00 43.54  ? 168 LEU A O   1 
ATOM   967  C CB  . LEU A 1 187 ? 103.776 111.411 125.848 1.00 43.54  ? 168 LEU A CB  1 
ATOM   968  C CG  . LEU A 1 187 ? 102.996 112.642 126.290 1.00 43.54  ? 168 LEU A CG  1 
ATOM   969  C CD1 . LEU A 1 187 ? 102.298 112.360 127.600 1.00 43.54  ? 168 LEU A CD1 1 
ATOM   970  C CD2 . LEU A 1 187 ? 103.919 113.829 126.421 1.00 43.54  ? 168 LEU A CD2 1 
ATOM   971  N N   . LEU A 1 188 ? 105.108 109.209 124.028 1.00 38.52  ? 169 LEU A N   1 
ATOM   972  C CA  . LEU A 1 188 ? 106.057 108.110 123.944 1.00 38.52  ? 169 LEU A CA  1 
ATOM   973  C C   . LEU A 1 188 ? 106.981 108.266 122.743 1.00 38.52  ? 169 LEU A C   1 
ATOM   974  O O   . LEU A 1 188 ? 108.151 107.875 122.810 1.00 38.52  ? 169 LEU A O   1 
ATOM   975  C CB  . LEU A 1 188 ? 105.308 106.782 123.899 1.00 38.52  ? 169 LEU A CB  1 
ATOM   976  C CG  . LEU A 1 188 ? 106.076 105.557 124.380 1.00 38.52  ? 169 LEU A CG  1 
ATOM   977  C CD1 . LEU A 1 188 ? 105.115 104.555 124.985 1.00 38.52  ? 169 LEU A CD1 1 
ATOM   978  C CD2 . LEU A 1 188 ? 106.845 104.931 123.243 1.00 38.52  ? 169 LEU A CD2 1 
ATOM   979  N N   . ALA A 1 189 ? 106.507 108.881 121.655 1.00 37.03  ? 170 ALA A N   1 
ATOM   980  C CA  . ALA A 1 189 ? 107.405 109.123 120.530 1.00 37.03  ? 170 ALA A CA  1 
ATOM   981  C C   . ALA A 1 189 ? 108.435 110.194 120.867 1.00 37.03  ? 170 ALA A C   1 
ATOM   982  O O   . ALA A 1 189 ? 109.609 110.074 120.492 1.00 37.03  ? 170 ALA A O   1 
ATOM   983  C CB  . ALA A 1 189 ? 106.609 109.514 119.290 1.00 37.03  ? 170 ALA A CB  1 
ATOM   984  N N   . ALA A 1 190 ? 108.027 111.237 121.590 1.00 34.76  ? 171 ALA A N   1 
ATOM   985  C CA  . ALA A 1 190 ? 108.991 112.245 122.014 1.00 34.76  ? 171 ALA A CA  1 
ATOM   986  C C   . ALA A 1 190 ? 110.000 111.660 122.990 1.00 34.76  ? 171 ALA A C   1 
ATOM   987  O O   . ALA A 1 190 ? 111.188 112.003 122.949 1.00 34.76  ? 171 ALA A O   1 
ATOM   988  C CB  . ALA A 1 190 ? 108.268 113.435 122.638 1.00 34.76  ? 171 ALA A CB  1 
ATOM   989  N N   . ALA A 1 191 ? 109.554 110.752 123.856 1.00 35.97  ? 172 ALA A N   1 
ATOM   990  C CA  . ALA A 1 191 ? 110.475 110.116 124.787 1.00 35.97  ? 172 ALA A CA  1 
ATOM   991  C C   . ALA A 1 191 ? 111.458 109.216 124.055 1.00 35.97  ? 172 ALA A C   1 
ATOM   992  O O   . ALA A 1 191 ? 112.646 109.180 124.393 1.00 35.97  ? 172 ALA A O   1 
ATOM   993  C CB  . ALA A 1 191 ? 109.696 109.323 125.827 1.00 35.97  ? 172 ALA A CB  1 
ATOM   994  N N   . CYS A 1 192 ? 110.984 108.489 123.043 1.00 32.52  ? 173 CYS A N   1 
ATOM   995  C CA  . CYS A 1 192 ? 111.879 107.672 122.230 1.00 32.52  ? 173 CYS A CA  1 
ATOM   996  C C   . CYS A 1 192 ? 112.920 108.525 121.517 1.00 32.52  ? 173 CYS A C   1 
ATOM   997  O O   . CYS A 1 192 ? 114.104 108.167 121.482 1.00 32.52  ? 173 CYS A O   1 
ATOM   998  C CB  . CYS A 1 192 ? 111.073 106.868 121.219 1.00 32.52  ? 173 CYS A CB  1 
ATOM   999  S SG  . CYS A 1 192 ? 112.048 106.226 119.863 1.00 32.52  ? 173 CYS A SG  1 
ATOM   1000 N N   . ILE A 1 193 ? 112.503 109.655 120.940 1.00 30.97  ? 174 ILE A N   1 
ATOM   1001 C CA  . ILE A 1 193 ? 113.459 110.515 120.247 1.00 30.97  ? 174 ILE A CA  1 
ATOM   1002 C C   . ILE A 1 193 ? 114.484 111.074 121.225 1.00 30.97  ? 174 ILE A C   1 
ATOM   1003 O O   . ILE A 1 193 ? 115.683 111.117 120.926 1.00 30.97  ? 174 ILE A O   1 
ATOM   1004 C CB  . ILE A 1 193 ? 112.736 111.640 119.490 1.00 30.97  ? 174 ILE A CB  1 
ATOM   1005 C CG1 . ILE A 1 193 ? 112.091 111.091 118.227 1.00 30.97  ? 174 ILE A CG1 1 
ATOM   1006 C CG2 . ILE A 1 193 ? 113.709 112.720 119.106 1.00 30.97  ? 174 ILE A CG2 1 
ATOM   1007 C CD1 . ILE A 1 193 ? 111.197 112.077 117.538 1.00 30.97  ? 174 ILE A CD1 1 
ATOM   1008 N N   . CYS A 1 194 ? 114.040 111.508 122.408 1.00 34.11  ? 175 CYS A N   1 
ATOM   1009 C CA  . CYS A 1 194 ? 114.987 112.043 123.381 1.00 34.11  ? 175 CYS A CA  1 
ATOM   1010 C C   . CYS A 1 194 ? 115.966 110.974 123.847 1.00 34.11  ? 175 CYS A C   1 
ATOM   1011 O O   . CYS A 1 194 ? 117.164 111.243 123.999 1.00 34.11  ? 175 CYS A O   1 
ATOM   1012 C CB  . CYS A 1 194 ? 114.245 112.642 124.571 1.00 34.11  ? 175 CYS A CB  1 
ATOM   1013 S SG  . CYS A 1 194 ? 113.396 114.187 124.207 1.00 34.11  ? 175 CYS A SG  1 
ATOM   1014 N N   . LEU A 1 195 ? 115.487 109.746 124.052 1.00 30.16  ? 176 LEU A N   1 
ATOM   1015 C CA  . LEU A 1 195 ? 116.384 108.680 124.482 1.00 30.16  ? 176 LEU A CA  1 
ATOM   1016 C C   . LEU A 1 195 ? 117.395 108.343 123.399 1.00 30.16  ? 176 LEU A C   1 
ATOM   1017 O O   . LEU A 1 195 ? 118.570 108.097 123.695 1.00 30.16  ? 176 LEU A O   1 
ATOM   1018 C CB  . LEU A 1 195 ? 115.589 107.436 124.864 1.00 30.16  ? 176 LEU A CB  1 
ATOM   1019 C CG  . LEU A 1 195 ? 116.407 106.153 124.967 1.00 30.16  ? 176 LEU A CG  1 
ATOM   1020 C CD1 . LEU A 1 195 ? 117.417 106.254 126.088 1.00 30.16  ? 176 LEU A CD1 1 
ATOM   1021 C CD2 . LEU A 1 195 ? 115.495 104.962 125.168 1.00 30.16  ? 176 LEU A CD2 1 
ATOM   1022 N N   . LEU A 1 196 ? 116.972 108.352 122.135 1.00 29.63  ? 177 LEU A N   1 
ATOM   1023 C CA  . LEU A 1 196 ? 117.913 108.021 121.072 1.00 29.63  ? 177 LEU A CA  1 
ATOM   1024 C C   . LEU A 1 196 ? 118.925 109.137 120.860 1.00 29.63  ? 177 LEU A C   1 
ATOM   1025 O O   . LEU A 1 196 ? 120.102 108.871 120.587 1.00 29.63  ? 177 LEU A O   1 
ATOM   1026 C CB  . LEU A 1 196 ? 117.169 107.718 119.782 1.00 29.63  ? 177 LEU A CB  1 
ATOM   1027 C CG  . LEU A 1 196 ? 116.935 106.226 119.630 1.00 29.63  ? 177 LEU A CG  1 
ATOM   1028 C CD1 . LEU A 1 196 ? 116.352 105.926 118.277 1.00 29.63  ? 177 LEU A CD1 1 
ATOM   1029 C CD2 . LEU A 1 196 ? 118.236 105.491 119.832 1.00 29.63  ? 177 LEU A CD2 1 
ATOM   1030 N N   . THR A 1 197 ? 118.498 110.390 121.002 1.00 27.97  ? 178 THR A N   1 
ATOM   1031 C CA  . THR A 1 197 ? 119.451 111.485 120.914 1.00 27.97  ? 178 THR A CA  1 
ATOM   1032 C C   . THR A 1 197 ? 120.459 111.426 122.052 1.00 27.97  ? 178 THR A C   1 
ATOM   1033 O O   . THR A 1 197 ? 121.655 111.641 121.834 1.00 27.97  ? 178 THR A O   1 
ATOM   1034 C CB  . THR A 1 197 ? 118.717 112.819 120.902 1.00 27.97  ? 178 THR A CB  1 
ATOM   1035 O OG1 . THR A 1 197 ? 118.198 113.053 119.589 1.00 27.97  ? 178 THR A OG1 1 
ATOM   1036 C CG2 . THR A 1 197 ? 119.647 113.947 121.273 1.00 27.97  ? 178 THR A CG2 1 
ATOM   1037 N N   . PHE A 1 198 ? 120.021 111.086 123.264 1.00 33.21  ? 179 PHE A N   1 
ATOM   1038 C CA  . PHE A 1 198 ? 120.985 110.981 124.355 1.00 33.21  ? 179 PHE A CA  1 
ATOM   1039 C C   . PHE A 1 198 ? 121.956 109.831 124.121 1.00 33.21  ? 179 PHE A C   1 
ATOM   1040 O O   . PHE A 1 198 ? 123.165 109.974 124.339 1.00 33.21  ? 179 PHE A O   1 
ATOM   1041 C CB  . PHE A 1 198 ? 120.288 110.807 125.698 1.00 33.21  ? 179 PHE A CB  1 
ATOM   1042 C CG  . PHE A 1 198 ? 121.243 110.586 126.830 1.00 33.21  ? 179 PHE A CG  1 
ATOM   1043 C CD1 . PHE A 1 198 ? 121.853 111.658 127.449 1.00 33.21  ? 179 PHE A CD1 1 
ATOM   1044 C CD2 . PHE A 1 198 ? 121.551 109.309 127.258 1.00 33.21  ? 179 PHE A CD2 1 
ATOM   1045 C CE1 . PHE A 1 198 ? 122.742 111.461 128.483 1.00 33.21  ? 179 PHE A CE1 1 
ATOM   1046 C CE2 . PHE A 1 198 ? 122.438 109.108 128.291 1.00 33.21  ? 179 PHE A CE2 1 
ATOM   1047 C CZ  . PHE A 1 198 ? 123.034 110.186 128.904 1.00 33.21  ? 179 PHE A CZ  1 
ATOM   1048 N N   . VAL A 1 199 ? 121.443 108.668 123.712 1.00 34.41  ? 180 VAL A N   1 
ATOM   1049 C CA  . VAL A 1 199 ? 122.325 107.548 123.394 1.00 34.41  ? 180 VAL A CA  1 
ATOM   1050 C C   . VAL A 1 199 ? 123.377 107.978 122.380 1.00 34.41  ? 180 VAL A C   1 
ATOM   1051 O O   . VAL A 1 199 ? 124.582 107.840 122.615 1.00 34.41  ? 180 VAL A O   1 
ATOM   1052 C CB  . VAL A 1 199 ? 121.514 106.341 122.894 1.00 34.41  ? 180 VAL A CB  1 
ATOM   1053 C CG1 . VAL A 1 199 ? 122.438 105.304 122.303 1.00 34.41  ? 180 VAL A CG1 1 
ATOM   1054 C CG2 . VAL A 1 199 ? 120.727 105.734 124.031 1.00 34.41  ? 180 VAL A CG2 1 
ATOM   1055 N N   . ASN A 1 200 ? 122.938 108.536 121.247 1.00 31.67  ? 181 ASN A N   1 
ATOM   1056 C CA  . ASN A 1 200 ? 123.883 108.909 120.197 1.00 31.67  ? 181 ASN A CA  1 
ATOM   1057 C C   . ASN A 1 200 ? 124.797 110.046 120.632 1.00 31.67  ? 181 ASN A C   1 
ATOM   1058 O O   . ASN A 1 200 ? 125.840 110.279 120.013 1.00 31.67  ? 181 ASN A O   1 
ATOM   1059 C CB  . ASN A 1 200 ? 123.134 109.295 118.929 1.00 31.67  ? 181 ASN A CB  1 
ATOM   1060 C CG  . ASN A 1 200 ? 122.705 108.103 118.137 1.00 31.67  ? 181 ASN A CG  1 
ATOM   1061 O OD1 . ASN A 1 200 ? 123.487 107.192 117.906 1.00 31.67  ? 181 ASN A OD1 1 
ATOM   1062 N ND2 . ASN A 1 200 ? 121.454 108.094 117.714 1.00 31.67  ? 181 ASN A ND2 1 
ATOM   1063 N N   . CYS A 1 201 ? 124.423 110.777 121.683 1.00 38.07  ? 182 CYS A N   1 
ATOM   1064 C CA  . CYS A 1 201 ? 125.320 111.807 122.191 1.00 38.07  ? 182 CYS A CA  1 
ATOM   1065 C C   . CYS A 1 201 ? 126.420 111.207 123.050 1.00 38.07  ? 182 CYS A C   1 
ATOM   1066 O O   . CYS A 1 201 ? 127.593 111.562 122.897 1.00 38.07  ? 182 CYS A O   1 
ATOM   1067 C CB  . CYS A 1 201 ? 124.546 112.851 122.990 1.00 38.07  ? 182 CYS A CB  1 
ATOM   1068 S SG  . CYS A 1 201 ? 123.790 114.149 122.011 1.00 38.07  ? 182 CYS A SG  1 
ATOM   1069 N N   . ALA A 1 202 ? 126.064 110.302 123.961 1.00 45.06  ? 183 ALA A N   1 
ATOM   1070 C CA  . ALA A 1 202 ? 127.021 109.858 124.970 1.00 45.06  ? 183 ALA A CA  1 
ATOM   1071 C C   . ALA A 1 202 ? 128.249 109.219 124.335 1.00 45.06  ? 183 ALA A C   1 
ATOM   1072 O O   . ALA A 1 202 ? 129.386 109.553 124.684 1.00 45.06  ? 183 ALA A O   1 
ATOM   1073 C CB  . ALA A 1 202 ? 126.346 108.889 125.935 1.00 45.06  ? 183 ALA A CB  1 
ATOM   1074 N N   . TYR A 1 203 ? 128.044 108.303 123.395 1.00 49.71  ? 184 TYR A N   1 
ATOM   1075 C CA  . TYR A 1 203 ? 129.140 107.619 122.726 1.00 49.71  ? 184 TYR A CA  1 
ATOM   1076 C C   . TYR A 1 203 ? 128.642 107.108 121.386 1.00 49.71  ? 184 TYR A C   1 
ATOM   1077 O O   . TYR A 1 203 ? 127.628 106.412 121.315 1.00 49.71  ? 184 TYR A O   1 
ATOM   1078 C CB  . TYR A 1 203 ? 129.684 106.431 123.531 1.00 49.71  ? 184 TYR A CB  1 
ATOM   1079 C CG  . TYR A 1 203 ? 130.375 106.768 124.831 1.00 49.71  ? 184 TYR A CG  1 
ATOM   1080 C CD1 . TYR A 1 203 ? 129.665 106.843 126.018 1.00 49.71  ? 184 TYR A CD1 1 
ATOM   1081 C CD2 . TYR A 1 203 ? 131.743 106.965 124.878 1.00 49.71  ? 184 TYR A CD2 1 
ATOM   1082 C CE1 . TYR A 1 203 ? 130.292 107.138 127.205 1.00 49.71  ? 184 TYR A CE1 1 
ATOM   1083 C CE2 . TYR A 1 203 ? 132.378 107.257 126.063 1.00 49.71  ? 184 TYR A CE2 1 
ATOM   1084 C CZ  . TYR A 1 203 ? 131.647 107.342 127.223 1.00 49.71  ? 184 TYR A CZ  1 
ATOM   1085 O OH  . TYR A 1 203 ? 132.276 107.633 128.408 1.00 49.71  ? 184 TYR A OH  1 
ATOM   1086 N N   . VAL A 1 204 ? 129.364 107.459 120.325 1.00 47.21  ? 185 VAL A N   1 
ATOM   1087 C CA  . VAL A 1 204 ? 129.008 106.973 118.996 1.00 47.21  ? 185 VAL A CA  1 
ATOM   1088 C C   . VAL A 1 204 ? 128.911 105.453 118.990 1.00 47.21  ? 185 VAL A C   1 
ATOM   1089 O O   . VAL A 1 204 ? 128.091 104.867 118.269 1.00 47.21  ? 185 VAL A O   1 
ATOM   1090 C CB  . VAL A 1 204 ? 130.019 107.490 117.957 1.00 47.21  ? 185 VAL A CB  1 
ATOM   1091 C CG1 . VAL A 1 204 ? 131.422 107.020 118.293 1.00 47.21  ? 185 VAL A CG1 1 
ATOM   1092 C CG2 . VAL A 1 204 ? 129.625 107.043 116.569 1.00 47.21  ? 185 VAL A CG2 1 
ATOM   1093 N N   . LYS A 1 205 ? 129.724 104.793 119.818 1.00 49.46  ? 186 LYS A N   1 
ATOM   1094 C CA  . LYS A 1 205 ? 129.644 103.342 119.925 1.00 49.46  ? 186 LYS A CA  1 
ATOM   1095 C C   . LYS A 1 205 ? 128.305 102.892 120.491 1.00 49.46  ? 186 LYS A C   1 
ATOM   1096 O O   . LYS A 1 205 ? 127.795 101.839 120.097 1.00 49.46  ? 186 LYS A O   1 
ATOM   1097 C CB  . LYS A 1 205 ? 130.790 102.810 120.781 1.00 49.46  ? 186 LYS A CB  1 
ATOM   1098 C CG  . LYS A 1 205 ? 130.929 101.303 120.741 1.00 49.46  ? 186 LYS A CG  1 
ATOM   1099 C CD  . LYS A 1 205 ? 131.055 100.806 119.317 1.00 49.46  ? 186 LYS A CD  1 
ATOM   1100 C CE  . LYS A 1 205 ? 132.264 101.408 118.626 1.00 49.46  ? 186 LYS A CE  1 
ATOM   1101 N NZ  . LYS A 1 205 ? 132.105 101.387 117.149 1.00 49.46  ? 186 LYS A NZ  1 
ATOM   1102 N N   . TRP A 1 206 ? 127.714 103.673 121.400 1.00 46.73  ? 187 TRP A N   1 
ATOM   1103 C CA  . TRP A 1 206 ? 126.383 103.334 121.892 1.00 46.73  ? 187 TRP A CA  1 
ATOM   1104 C C   . TRP A 1 206 ? 125.360 103.384 120.768 1.00 46.73  ? 187 TRP A C   1 
ATOM   1105 O O   . TRP A 1 206 ? 124.478 102.522 120.684 1.00 46.73  ? 187 TRP A O   1 
ATOM   1106 C CB  . TRP A 1 206 ? 125.971 104.273 123.022 1.00 46.73  ? 187 TRP A CB  1 
ATOM   1107 C CG  . TRP A 1 206 ? 126.642 103.980 124.316 1.00 46.73  ? 187 TRP A CG  1 
ATOM   1108 C CD1 . TRP A 1 206 ? 127.653 103.096 124.528 1.00 46.73  ? 187 TRP A CD1 1 
ATOM   1109 C CD2 . TRP A 1 206 ? 126.346 104.565 125.586 1.00 46.73  ? 187 TRP A CD2 1 
ATOM   1110 N NE1 . TRP A 1 206 ? 128.012 103.098 125.853 1.00 46.73  ? 187 TRP A NE1 1 
ATOM   1111 C CE2 . TRP A 1 206 ? 127.221 103.993 126.523 1.00 46.73  ? 187 TRP A CE2 1 
ATOM   1112 C CE3 . TRP A 1 206 ? 125.427 105.520 126.021 1.00 46.73  ? 187 TRP A CE3 1 
ATOM   1113 C CZ2 . TRP A 1 206 ? 127.204 104.343 127.866 1.00 46.73  ? 187 TRP A CZ2 1 
ATOM   1114 C CZ3 . TRP A 1 206 ? 125.412 105.866 127.354 1.00 46.73  ? 187 TRP A CZ3 1 
ATOM   1115 C CH2 . TRP A 1 206 ? 126.293 105.281 128.261 1.00 46.73  ? 187 TRP A CH2 1 
ATOM   1116 N N   . GLY A 1 207 ? 125.470 104.378 119.889 1.00 45.31  ? 188 GLY A N   1 
ATOM   1117 C CA  . GLY A 1 207 ? 124.575 104.440 118.749 1.00 45.31  ? 188 GLY A CA  1 
ATOM   1118 C C   . GLY A 1 207 ? 124.748 103.263 117.812 1.00 45.31  ? 188 GLY A C   1 
ATOM   1119 O O   . GLY A 1 207 ? 123.766 102.663 117.363 1.00 45.31  ? 188 GLY A O   1 
ATOM   1120 N N   . THR A 1 208 ? 125.998 102.909 117.510 1.00 45.18  ? 189 THR A N   1 
ATOM   1121 C CA  . THR A 1 208 ? 126.225 101.767 116.632 1.00 45.18  ? 189 THR A CA  1 
ATOM   1122 C C   . THR A 1 208 ? 125.718 100.478 117.264 1.00 45.18  ? 189 THR A C   1 
ATOM   1123 O O   . THR A 1 208 ? 125.175 99.616  116.567 1.00 45.18  ? 189 THR A O   1 
ATOM   1124 C CB  . THR A 1 208 ? 127.705 101.636 116.290 1.00 45.18  ? 189 THR A CB  1 
ATOM   1125 O OG1 . THR A 1 208 ? 128.488 101.800 117.477 1.00 45.18  ? 189 THR A OG1 1 
ATOM   1126 C CG2 . THR A 1 208 ? 128.104 102.682 115.273 1.00 45.18  ? 189 THR A CG2 1 
ATOM   1127 N N   . ARG A 1 209 ? 125.849 100.340 118.586 1.00 45.87  ? 190 ARG A N   1 
ATOM   1128 C CA  . ARG A 1 209 ? 125.396 99.117  119.240 1.00 45.87  ? 190 ARG A CA  1 
ATOM   1129 C C   . ARG A 1 209 ? 123.877 99.039  119.281 1.00 45.87  ? 190 ARG A C   1 
ATOM   1130 O O   . ARG A 1 209 ? 123.305 97.966  119.065 1.00 45.87  ? 190 ARG A O   1 
ATOM   1131 C CB  . ARG A 1 209 ? 125.970 99.022  120.651 1.00 45.87  ? 190 ARG A CB  1 
ATOM   1132 C CG  . ARG A 1 209 ? 125.817 97.648  121.274 1.00 45.87  ? 190 ARG A CG  1 
ATOM   1133 C CD  . ARG A 1 209 ? 126.536 97.561  122.612 1.00 45.87  ? 190 ARG A CD  1 
ATOM   1134 N NE  . ARG A 1 209 ? 127.986 97.655  122.468 1.00 45.87  ? 190 ARG A NE  1 
ATOM   1135 C CZ  . ARG A 1 209 ? 128.844 97.633  123.484 1.00 45.87  ? 190 ARG A CZ  1 
ATOM   1136 N NH1 . ARG A 1 209 ? 128.399 97.517  124.727 1.00 45.87  ? 190 ARG A NH1 1 
ATOM   1137 N NH2 . ARG A 1 209 ? 130.147 97.724  123.257 1.00 45.87  ? 190 ARG A NH2 1 
ATOM   1138 N N   . VAL A 1 210 ? 123.205 100.156 119.569 1.00 37.90  ? 191 VAL A N   1 
ATOM   1139 C CA  . VAL A 1 210 ? 121.746 100.178 119.506 1.00 37.90  ? 191 VAL A CA  1 
ATOM   1140 C C   . VAL A 1 210 ? 121.274 99.786  118.114 1.00 37.90  ? 191 VAL A C   1 
ATOM   1141 O O   . VAL A 1 210 ? 120.407 98.915  117.951 1.00 37.90  ? 191 VAL A O   1 
ATOM   1142 C CB  . VAL A 1 210 ? 121.207 101.558 119.912 1.00 37.90  ? 191 VAL A CB  1 
ATOM   1143 C CG1 . VAL A 1 210 ? 119.802 101.738 119.394 1.00 37.90  ? 191 VAL A CG1 1 
ATOM   1144 C CG2 . VAL A 1 210 ? 121.230 101.700 121.411 1.00 37.90  ? 191 VAL A CG2 1 
ATOM   1145 N N   . GLN A 1 211 ? 121.842 100.424 117.086 1.00 37.21  ? 192 GLN A N   1 
ATOM   1146 C CA  . GLN A 1 211 ? 121.436 100.127 115.717 1.00 37.21  ? 192 GLN A CA  1 
ATOM   1147 C C   . GLN A 1 211 ? 121.680 98.667  115.369 1.00 37.21  ? 192 GLN A C   1 
ATOM   1148 O O   . GLN A 1 211 ? 120.822 98.016  114.764 1.00 37.21  ? 192 GLN A O   1 
ATOM   1149 C CB  . GLN A 1 211 ? 122.180 101.031 114.742 1.00 37.21  ? 192 GLN A CB  1 
ATOM   1150 C CG  . GLN A 1 211 ? 122.024 100.611 113.311 1.00 37.21  ? 192 GLN A CG  1 
ATOM   1151 C CD  . GLN A 1 211 ? 120.599 100.702 112.848 1.00 37.21  ? 192 GLN A CD  1 
ATOM   1152 O OE1 . GLN A 1 211 ? 120.138 101.759 112.437 1.00 37.21  ? 192 GLN A OE1 1 
ATOM   1153 N NE2 . GLN A 1 211 ? 119.888 99.590  112.909 1.00 37.21  ? 192 GLN A NE2 1 
ATOM   1154 N N   . ASP A 1 212 ? 122.835 98.130  115.759 1.00 42.90  ? 193 ASP A N   1 
ATOM   1155 C CA  . ASP A 1 212 ? 123.160 96.748  115.435 1.00 42.90  ? 193 ASP A CA  1 
ATOM   1156 C C   . ASP A 1 212 ? 122.205 95.784  116.126 1.00 42.90  ? 193 ASP A C   1 
ATOM   1157 O O   . ASP A 1 212 ? 121.651 94.878  115.492 1.00 42.90  ? 193 ASP A O   1 
ATOM   1158 C CB  . ASP A 1 212 ? 124.604 96.455  115.831 1.00 42.90  ? 193 ASP A CB  1 
ATOM   1159 C CG  . ASP A 1 212 ? 125.075 95.107  115.350 1.00 42.90  ? 193 ASP A CG  1 
ATOM   1160 O OD1 . ASP A 1 212 ? 124.376 94.497  114.517 1.00 42.90  ? 193 ASP A OD1 1 
ATOM   1161 O OD2 . ASP A 1 212 ? 126.148 94.659  115.803 1.00 42.90  ? 193 ASP A OD2 1 
ATOM   1162 N N   . THR A 1 213 ? 122.001 95.964  117.432 1.00 40.15  ? 194 THR A N   1 
ATOM   1163 C CA  . THR A 1 213 ? 121.104 95.085  118.171 1.00 40.15  ? 194 THR A CA  1 
ATOM   1164 C C   . THR A 1 213 ? 119.702 95.105  117.580 1.00 40.15  ? 194 THR A C   1 
ATOM   1165 O O   . THR A 1 213 ? 119.076 94.051  117.404 1.00 40.15  ? 194 THR A O   1 
ATOM   1166 C CB  . THR A 1 213 ? 121.072 95.494  119.643 1.00 40.15  ? 194 THR A CB  1 
ATOM   1167 O OG1 . THR A 1 213 ? 122.349 95.240  120.239 1.00 40.15  ? 194 THR A OG1 1 
ATOM   1168 C CG2 . THR A 1 213 ? 120.017 94.715  120.388 1.00 40.15  ? 194 THR A CG2 1 
ATOM   1169 N N   . PHE A 1 214 ? 119.198 96.286  117.224 1.00 39.50  ? 195 PHE A N   1 
ATOM   1170 C CA  . PHE A 1 214 ? 117.800 96.331  116.821 1.00 39.50  ? 195 PHE A CA  1 
ATOM   1171 C C   . PHE A 1 214 ? 117.601 95.930  115.366 1.00 39.50  ? 195 PHE A C   1 
ATOM   1172 O O   . PHE A 1 214 ? 116.543 95.384  115.024 1.00 39.50  ? 195 PHE A O   1 
ATOM   1173 C CB  . PHE A 1 214 ? 117.214 97.709  117.114 1.00 39.50  ? 195 PHE A CB  1 
ATOM   1174 C CG  . PHE A 1 214 ? 116.867 97.900  118.559 1.00 39.50  ? 195 PHE A CG  1 
ATOM   1175 C CD1 . PHE A 1 214 ? 117.788 97.602  119.543 1.00 39.50  ? 195 PHE A CD1 1 
ATOM   1176 C CD2 . PHE A 1 214 ? 115.626 98.354  118.938 1.00 39.50  ? 195 PHE A CD2 1 
ATOM   1177 C CE1 . PHE A 1 214 ? 117.482 97.758  120.868 1.00 39.50  ? 195 PHE A CE1 1 
ATOM   1178 C CE2 . PHE A 1 214 ? 115.315 98.504  120.270 1.00 39.50  ? 195 PHE A CE2 1 
ATOM   1179 C CZ  . PHE A 1 214 ? 116.247 98.211  121.233 1.00 39.50  ? 195 PHE A CZ  1 
ATOM   1180 N N   . THR A 1 215 ? 118.602 96.118  114.504 1.00 41.22  ? 196 THR A N   1 
ATOM   1181 C CA  . THR A 1 215 ? 118.464 95.551  113.170 1.00 41.22  ? 196 THR A CA  1 
ATOM   1182 C C   . THR A 1 215 ? 118.621 94.038  113.213 1.00 41.22  ? 196 THR A C   1 
ATOM   1183 O O   . THR A 1 215 ? 117.982 93.328  112.430 1.00 41.22  ? 196 THR A O   1 
ATOM   1184 C CB  . THR A 1 215 ? 119.456 96.173  112.192 1.00 41.22  ? 196 THR A CB  1 
ATOM   1185 O OG1 . THR A 1 215 ? 119.111 95.769  110.865 1.00 41.22  ? 196 THR A OG1 1 
ATOM   1186 C CG2 . THR A 1 215 ? 120.861 95.709  112.472 1.00 41.22  ? 196 THR A CG2 1 
ATOM   1187 N N   . TYR A 1 216 ? 119.415 93.517  114.157 1.00 45.53  ? 197 TYR A N   1 
ATOM   1188 C CA  . TYR A 1 216 ? 119.390 92.081  114.415 1.00 45.53  ? 197 TYR A CA  1 
ATOM   1189 C C   . TYR A 1 216 ? 117.994 91.624  114.804 1.00 45.53  ? 197 TYR A C   1 
ATOM   1190 O O   . TYR A 1 216 ? 117.492 90.622  114.283 1.00 45.53  ? 197 TYR A O   1 
ATOM   1191 C CB  . TYR A 1 216 ? 120.372 91.714  115.524 1.00 45.53  ? 197 TYR A CB  1 
ATOM   1192 C CG  . TYR A 1 216 ? 121.821 91.646  115.121 1.00 45.53  ? 197 TYR A CG  1 
ATOM   1193 C CD1 . TYR A 1 216 ? 122.194 91.573  113.790 1.00 45.53  ? 197 TYR A CD1 1 
ATOM   1194 C CD2 . TYR A 1 216 ? 122.818 91.629  116.083 1.00 45.53  ? 197 TYR A CD2 1 
ATOM   1195 C CE1 . TYR A 1 216 ? 123.523 91.495  113.431 1.00 45.53  ? 197 TYR A CE1 1 
ATOM   1196 C CE2 . TYR A 1 216 ? 124.143 91.554  115.736 1.00 45.53  ? 197 TYR A CE2 1 
ATOM   1197 C CZ  . TYR A 1 216 ? 124.493 91.489  114.410 1.00 45.53  ? 197 TYR A CZ  1 
ATOM   1198 O OH  . TYR A 1 216 ? 125.821 91.412  114.067 1.00 45.53  ? 197 TYR A OH  1 
ATOM   1199 N N   . ALA A 1 217 ? 117.354 92.351  115.721 1.00 45.23  ? 198 ALA A N   1 
ATOM   1200 C CA  . ALA A 1 217 ? 116.030 91.958  116.193 1.00 45.23  ? 198 ALA A CA  1 
ATOM   1201 C C   . ALA A 1 217 ? 115.021 91.919  115.052 1.00 45.23  ? 198 ALA A C   1 
ATOM   1202 O O   . ALA A 1 217 ? 114.291 90.935  114.884 1.00 45.23  ? 198 ALA A O   1 
ATOM   1203 C CB  . ALA A 1 217 ? 115.561 92.912  117.290 1.00 45.23  ? 198 ALA A CB  1 
ATOM   1204 N N   . LYS A 1 218 ? 114.966 92.980  114.245 1.00 44.79  ? 199 LYS A N   1 
ATOM   1205 C CA  . LYS A 1 218 ? 113.945 93.000  113.202 1.00 44.79  ? 199 LYS A CA  1 
ATOM   1206 C C   . LYS A 1 218 ? 114.291 92.078  112.038 1.00 44.79  ? 199 LYS A C   1 
ATOM   1207 O O   . LYS A 1 218 ? 113.382 91.554  111.384 1.00 44.79  ? 199 LYS A O   1 
ATOM   1208 C CB  . LYS A 1 218 ? 113.694 94.419  112.712 1.00 44.79  ? 199 LYS A CB  1 
ATOM   1209 C CG  . LYS A 1 218 ? 114.770 95.004  111.850 1.00 44.79  ? 199 LYS A CG  1 
ATOM   1210 C CD  . LYS A 1 218 ? 114.555 96.490  111.786 1.00 44.79  ? 199 LYS A CD  1 
ATOM   1211 C CE  . LYS A 1 218 ? 115.709 97.205  111.165 1.00 44.79  ? 199 LYS A CE  1 
ATOM   1212 N NZ  . LYS A 1 218 ? 115.402 98.655  111.077 1.00 44.79  ? 199 LYS A NZ  1 
ATOM   1213 N N   . VAL A 1 219 ? 115.576 91.824  111.776 1.00 47.89  ? 200 VAL A N   1 
ATOM   1214 C CA  . VAL A 1 219 ? 115.888 90.828  110.760 1.00 47.89  ? 200 VAL A CA  1 
ATOM   1215 C C   . VAL A 1 219 ? 115.520 89.435  111.252 1.00 47.89  ? 200 VAL A C   1 
ATOM   1216 O O   . VAL A 1 219 ? 115.056 88.601  110.470 1.00 47.89  ? 200 VAL A O   1 
ATOM   1217 C CB  . VAL A 1 219 ? 117.367 90.922  110.348 1.00 47.89  ? 200 VAL A CB  1 
ATOM   1218 C CG1 . VAL A 1 219 ? 117.826 89.635  109.687 1.00 47.89  ? 200 VAL A CG1 1 
ATOM   1219 C CG2 . VAL A 1 219 ? 117.565 92.089  109.405 1.00 47.89  ? 200 VAL A CG2 1 
ATOM   1220 N N   . VAL A 1 220 ? 115.666 89.167  112.552 1.00 51.36  ? 201 VAL A N   1 
ATOM   1221 C CA  . VAL A 1 220 ? 115.207 87.889  113.090 1.00 51.36  ? 201 VAL A CA  1 
ATOM   1222 C C   . VAL A 1 220 ? 113.691 87.778  112.986 1.00 51.36  ? 201 VAL A C   1 
ATOM   1223 O O   . VAL A 1 220 ? 113.155 86.712  112.665 1.00 51.36  ? 201 VAL A O   1 
ATOM   1224 C CB  . VAL A 1 220 ? 115.694 87.703  114.537 1.00 51.36  ? 201 VAL A CB  1 
ATOM   1225 C CG1 . VAL A 1 220 ? 115.020 86.506  115.173 1.00 51.36  ? 201 VAL A CG1 1 
ATOM   1226 C CG2 . VAL A 1 220 ? 117.197 87.504  114.556 1.00 51.36  ? 201 VAL A CG2 1 
ATOM   1227 N N   . ALA A 1 221 ? 112.974 88.871  113.249 1.00 52.24  ? 202 ALA A N   1 
ATOM   1228 C CA  . ALA A 1 221 ? 111.518 88.830  113.128 1.00 52.24  ? 202 ALA A CA  1 
ATOM   1229 C C   . ALA A 1 221 ? 111.085 88.571  111.690 1.00 52.24  ? 202 ALA A C   1 
ATOM   1230 O O   . ALA A 1 221 ? 110.162 87.783  111.439 1.00 52.24  ? 202 ALA A O   1 
ATOM   1231 C CB  . ALA A 1 221 ? 110.910 90.131  113.636 1.00 52.24  ? 202 ALA A CB  1 
ATOM   1232 N N   . LEU A 1 222 ? 111.744 89.215  110.725 1.00 50.10  ? 203 LEU A N   1 
ATOM   1233 C CA  . LEU A 1 222 ? 111.389 88.964  109.334 1.00 50.10  ? 203 LEU A CA  1 
ATOM   1234 C C   . LEU A 1 222 ? 111.813 87.572  108.892 1.00 50.10  ? 203 LEU A C   1 
ATOM   1235 O O   . LEU A 1 222 ? 111.155 86.968  108.039 1.00 50.10  ? 203 LEU A O   1 
ATOM   1236 C CB  . LEU A 1 222 ? 111.990 90.033  108.431 1.00 50.10  ? 203 LEU A CB  1 
ATOM   1237 C CG  . LEU A 1 222 ? 110.999 91.180  108.275 1.00 50.10  ? 203 LEU A CG  1 
ATOM   1238 C CD1 . LEU A 1 222 ? 111.459 92.200  107.268 1.00 50.10  ? 203 LEU A CD1 1 
ATOM   1239 C CD2 . LEU A 1 222 ? 109.651 90.626  107.880 1.00 50.10  ? 203 LEU A CD2 1 
ATOM   1240 N N   . ILE A 1 223 ? 112.883 87.033  109.477 1.00 54.91  ? 204 ILE A N   1 
ATOM   1241 C CA  . ILE A 1 223 ? 113.232 85.639  109.232 1.00 54.91  ? 204 ILE A CA  1 
ATOM   1242 C C   . ILE A 1 223 ? 112.132 84.726  109.748 1.00 54.91  ? 204 ILE A C   1 
ATOM   1243 O O   . ILE A 1 223 ? 111.769 83.743  109.098 1.00 54.91  ? 204 ILE A O   1 
ATOM   1244 C CB  . ILE A 1 223 ? 114.591 85.307  109.871 1.00 54.91  ? 204 ILE A CB  1 
ATOM   1245 C CG1 . ILE A 1 223 ? 115.724 85.801  108.978 1.00 54.91  ? 204 ILE A CG1 1 
ATOM   1246 C CG2 . ILE A 1 223 ? 114.720 83.816  110.108 1.00 54.91  ? 204 ILE A CG2 1 
ATOM   1247 C CD1 . ILE A 1 223 ? 115.655 85.258  107.572 1.00 54.91  ? 204 ILE A CD1 1 
ATOM   1248 N N   . ALA A 1 224 ? 111.578 85.042  110.918 1.00 59.66  ? 205 ALA A N   1 
ATOM   1249 C CA  . ALA A 1 224 ? 110.472 84.250  111.445 1.00 59.66  ? 205 ALA A CA  1 
ATOM   1250 C C   . ALA A 1 224 ? 109.275 84.290  110.506 1.00 59.66  ? 205 ALA A C   1 
ATOM   1251 O O   . ALA A 1 224 ? 108.656 83.253  110.227 1.00 59.66  ? 205 ALA A O   1 
ATOM   1252 C CB  . ALA A 1 224 ? 110.080 84.746  112.835 1.00 59.66  ? 205 ALA A CB  1 
ATOM   1253 N N   . ILE A 1 225 ? 108.937 85.478  110.003 1.00 59.92  ? 206 ILE A N   1 
ATOM   1254 C CA  . ILE A 1 225 ? 107.814 85.595  109.073 1.00 59.92  ? 206 ILE A CA  1 
ATOM   1255 C C   . ILE A 1 225 ? 108.071 84.766  107.819 1.00 59.92  ? 206 ILE A C   1 
ATOM   1256 O O   . ILE A 1 225 ? 107.208 84.002  107.370 1.00 59.92  ? 206 ILE A O   1 
ATOM   1257 C CB  . ILE A 1 225 ? 107.544 87.069  108.724 1.00 59.92  ? 206 ILE A CB  1 
ATOM   1258 C CG1 . ILE A 1 225 ? 106.699 87.728  109.809 1.00 59.92  ? 206 ILE A CG1 1 
ATOM   1259 C CG2 . ILE A 1 225 ? 106.834 87.178  107.392 1.00 59.92  ? 206 ILE A CG2 1 
ATOM   1260 C CD1 . ILE A 1 225 ? 106.350 89.165  109.504 1.00 59.92  ? 206 ILE A CD1 1 
ATOM   1261 N N   . ILE A 1 226 ? 109.260 84.911  107.229 1.00 60.20  ? 207 ILE A N   1 
ATOM   1262 C CA  . ILE A 1 226 ? 109.569 84.194  105.994 1.00 60.20  ? 207 ILE A CA  1 
ATOM   1263 C C   . ILE A 1 226 ? 109.549 82.690  106.226 1.00 60.20  ? 207 ILE A C   1 
ATOM   1264 O O   . ILE A 1 226 ? 109.075 81.923  105.380 1.00 60.20  ? 207 ILE A O   1 
ATOM   1265 C CB  . ILE A 1 226 ? 110.923 84.661  105.432 1.00 60.20  ? 207 ILE A CB  1 
ATOM   1266 C CG1 . ILE A 1 226 ? 110.819 86.093  104.919 1.00 60.20  ? 207 ILE A CG1 1 
ATOM   1267 C CG2 . ILE A 1 226 ? 111.381 83.748  104.314 1.00 60.20  ? 207 ILE A CG2 1 
ATOM   1268 C CD1 . ILE A 1 226 ? 112.149 86.694  104.563 1.00 60.20  ? 207 ILE A CD1 1 
ATOM   1269 N N   . VAL A 1 227 ? 110.047 82.244  107.380 1.00 70.62  ? 208 VAL A N   1 
ATOM   1270 C CA  . VAL A 1 227 ? 110.093 80.814  107.661 1.00 70.62  ? 208 VAL A CA  1 
ATOM   1271 C C   . VAL A 1 227 ? 108.691 80.255  107.839 1.00 70.62  ? 208 VAL A C   1 
ATOM   1272 O O   . VAL A 1 227 ? 108.374 79.182  107.317 1.00 70.62  ? 208 VAL A O   1 
ATOM   1273 C CB  . VAL A 1 227 ? 110.979 80.536  108.888 1.00 70.62  ? 208 VAL A CB  1 
ATOM   1274 C CG1 . VAL A 1 227 ? 110.806 79.103  109.347 1.00 70.62  ? 208 VAL A CG1 1 
ATOM   1275 C CG2 . VAL A 1 227 ? 112.432 80.778  108.536 1.00 70.62  ? 208 VAL A CG2 1 
ATOM   1276 N N   . MET A 1 228 ? 107.826 80.964  108.568 1.00 75.87  ? 209 MET A N   1 
ATOM   1277 C CA  . MET A 1 228 ? 106.456 80.482  108.712 1.00 75.87  ? 209 MET A CA  1 
ATOM   1278 C C   . MET A 1 228 ? 105.740 80.467  107.367 1.00 75.87  ? 209 MET A C   1 
ATOM   1279 O O   . MET A 1 228 ? 104.988 79.531  107.063 1.00 75.87  ? 209 MET A O   1 
ATOM   1280 C CB  . MET A 1 228 ? 105.693 81.336  109.724 1.00 75.87  ? 209 MET A CB  1 
ATOM   1281 C CG  . MET A 1 228 ? 106.162 81.167  111.165 1.00 75.87  ? 209 MET A CG  1 
ATOM   1282 S SD  . MET A 1 228 ? 106.588 79.469  111.609 1.00 75.87  ? 209 MET A SD  1 
ATOM   1283 C CE  . MET A 1 228 ? 104.970 78.707  111.695 1.00 75.87  ? 209 MET A CE  1 
ATOM   1284 N N   . GLY A 1 229 ? 105.986 81.480  106.534 1.00 76.00  ? 210 GLY A N   1 
ATOM   1285 C CA  . GLY A 1 229 ? 105.375 81.500  105.216 1.00 76.00  ? 210 GLY A CA  1 
ATOM   1286 C C   . GLY A 1 229 ? 105.819 80.338  104.351 1.00 76.00  ? 210 GLY A C   1 
ATOM   1287 O O   . GLY A 1 229 ? 104.996 79.676  103.715 1.00 76.00  ? 210 GLY A O   1 
ATOM   1288 N N   . LEU A 1 230 ? 107.125 80.061  104.327 1.00 83.18  ? 211 LEU A N   1 
ATOM   1289 C CA  . LEU A 1 230 ? 107.633 78.955  103.522 1.00 83.18  ? 211 LEU A CA  1 
ATOM   1290 C C   . LEU A 1 230 ? 107.207 77.606  104.083 1.00 83.18  ? 211 LEU A C   1 
ATOM   1291 O O   . LEU A 1 230 ? 106.992 76.662  103.315 1.00 83.18  ? 211 LEU A O   1 
ATOM   1292 C CB  . LEU A 1 230 ? 109.156 79.028  103.409 1.00 83.18  ? 211 LEU A CB  1 
ATOM   1293 C CG  . LEU A 1 230 ? 109.742 79.814  102.231 1.00 83.18  ? 211 LEU A CG  1 
ATOM   1294 C CD1 . LEU A 1 230 ? 109.392 79.134  100.921 1.00 83.18  ? 211 LEU A CD1 1 
ATOM   1295 C CD2 . LEU A 1 230 ? 109.269 81.256  102.217 1.00 83.18  ? 211 LEU A CD2 1 
ATOM   1296 N N   . VAL A 1 231 ? 107.072 77.491  105.405 1.00 86.44  ? 212 VAL A N   1 
ATOM   1297 C CA  . VAL A 1 231 ? 106.563 76.253  105.986 1.00 86.44  ? 212 VAL A CA  1 
ATOM   1298 C C   . VAL A 1 231 ? 105.129 76.015  105.533 1.00 86.44  ? 212 VAL A C   1 
ATOM   1299 O O   . VAL A 1 231 ? 104.790 74.935  105.038 1.00 86.44  ? 212 VAL A O   1 
ATOM   1300 C CB  . VAL A 1 231 ? 106.676 76.289  107.520 1.00 86.44  ? 212 VAL A CB  1 
ATOM   1301 C CG1 . VAL A 1 231 ? 105.716 75.294  108.147 1.00 86.44  ? 212 VAL A CG1 1 
ATOM   1302 C CG2 . VAL A 1 231 ? 108.101 75.986  107.949 1.00 86.44  ? 212 VAL A CG2 1 
ATOM   1303 N N   . LYS A 1 232 ? 104.268 77.026  105.683 1.00 92.13  ? 213 LYS A N   1 
ATOM   1304 C CA  . LYS A 1 232 ? 102.886 76.881  105.233 1.00 92.13  ? 213 LYS A CA  1 
ATOM   1305 C C   . LYS A 1 232 ? 102.815 76.608  103.735 1.00 92.13  ? 213 LYS A C   1 
ATOM   1306 O O   . LYS A 1 232 ? 101.934 75.875  103.271 1.00 92.13  ? 213 LYS A O   1 
ATOM   1307 C CB  . LYS A 1 232 ? 102.079 78.128  105.590 1.00 92.13  ? 213 LYS A CB  1 
ATOM   1308 C CG  . LYS A 1 232 ? 101.618 78.168  107.033 1.00 92.13  ? 213 LYS A CG  1 
ATOM   1309 C CD  . LYS A 1 232 ? 100.608 77.070  107.318 1.00 92.13  ? 213 LYS A CD  1 
ATOM   1310 C CE  . LYS A 1 232 ? 100.085 77.159  108.742 1.00 92.13  ? 213 LYS A CE  1 
ATOM   1311 N NZ  . LYS A 1 232 ? 99.257  75.976  109.108 1.00 92.13  ? 213 LYS A NZ  1 
ATOM   1312 N N   . LEU A 1 233 ? 103.735 77.188  102.961 1.00 91.28  ? 214 LEU A N   1 
ATOM   1313 C CA  . LEU A 1 233 ? 103.736 76.982  101.517 1.00 91.28  ? 214 LEU A CA  1 
ATOM   1314 C C   . LEU A 1 233 ? 104.102 75.546  101.166 1.00 91.28  ? 214 LEU A C   1 
ATOM   1315 O O   . LEU A 1 233 ? 103.305 74.813  100.571 1.00 91.28  ? 214 LEU A O   1 
ATOM   1316 C CB  . LEU A 1 233 ? 104.707 77.963  100.857 1.00 91.28  ? 214 LEU A CB  1 
ATOM   1317 C CG  . LEU A 1 233 ? 105.023 77.746  99.377  1.00 91.28  ? 214 LEU A CG  1 
ATOM   1318 C CD1 . LEU A 1 233 ? 103.819 78.080  98.514  1.00 91.28  ? 214 LEU A CD1 1 
ATOM   1319 C CD2 . LEU A 1 233 ? 106.223 78.577  98.964  1.00 91.28  ? 214 LEU A CD2 1 
ATOM   1320 N N   . CYS A 1 234 ? 105.306 75.124  101.537 1.00 99.06  ? 215 CYS A N   1 
ATOM   1321 C CA  . CYS A 1 234 ? 105.814 73.821  101.134 1.00 99.06  ? 215 CYS A CA  1 
ATOM   1322 C C   . CYS A 1 234 ? 105.340 72.681  102.026 1.00 99.06  ? 215 CYS A C   1 
ATOM   1323 O O   . CYS A 1 234 ? 105.790 71.547  101.831 1.00 99.06  ? 215 CYS A O   1 
ATOM   1324 C CB  . CYS A 1 234 ? 107.346 73.841  101.105 1.00 99.06  ? 215 CYS A CB  1 
ATOM   1325 S SG  . CYS A 1 234 ? 108.062 74.415  99.544  1.00 99.06  ? 215 CYS A SG  1 
ATOM   1326 N N   . GLN A 1 235 ? 104.455 72.932  102.991 1.00 102.08 ? 216 GLN A N   1 
ATOM   1327 C CA  . GLN A 1 235 ? 103.990 71.834  103.824 1.00 102.08 ? 216 GLN A CA  1 
ATOM   1328 C C   . GLN A 1 235 ? 102.939 70.999  103.108 1.00 102.08 ? 216 GLN A C   1 
ATOM   1329 O O   . GLN A 1 235 ? 103.185 69.834  102.780 1.00 102.08 ? 216 GLN A O   1 
ATOM   1330 C CB  . GLN A 1 235 ? 103.428 72.385  105.137 1.00 102.08 ? 216 GLN A CB  1 
ATOM   1331 C CG  . GLN A 1 235 ? 103.084 71.336  106.174 1.00 102.08 ? 216 GLN A CG  1 
ATOM   1332 C CD  . GLN A 1 235 ? 102.563 71.951  107.458 1.00 102.08 ? 216 GLN A CD  1 
ATOM   1333 O OE1 . GLN A 1 235 ? 103.195 71.851  108.509 1.00 102.08 ? 216 GLN A OE1 1 
ATOM   1334 N NE2 . GLN A 1 235 ? 101.405 72.595  107.377 1.00 102.08 ? 216 GLN A NE2 1 
ATOM   1335 N N   . GLY A 1 236 ? 101.768 71.580  102.859 1.00 104.24 ? 217 GLY A N   1 
ATOM   1336 C CA  . GLY A 1 236 ? 100.741 70.859  102.136 1.00 104.24 ? 217 GLY A CA  1 
ATOM   1337 C C   . GLY A 1 236 ? 99.782  71.692  101.313 1.00 104.24 ? 217 GLY A C   1 
ATOM   1338 O O   . GLY A 1 236 ? 98.807  71.148  100.785 1.00 104.24 ? 217 GLY A O   1 
ATOM   1339 N N   . HIS A 1 237 ? 100.019 72.998  101.182 1.00 102.30 ? 218 HIS A N   1 
ATOM   1340 C CA  . HIS A 1 237 ? 98.962  73.891  100.724 1.00 102.30 ? 218 HIS A CA  1 
ATOM   1341 C C   . HIS A 1 237 ? 99.225  74.488  99.347  1.00 102.30 ? 218 HIS A C   1 
ATOM   1342 O O   . HIS A 1 237 ? 98.469  74.202  98.415  1.00 102.30 ? 218 HIS A O   1 
ATOM   1343 C CB  . HIS A 1 237 ? 98.765  75.007  101.759 1.00 102.30 ? 218 HIS A CB  1 
ATOM   1344 C CG  . HIS A 1 237 ? 98.633  74.512  103.166 1.00 102.30 ? 218 HIS A CG  1 
ATOM   1345 N ND1 . HIS A 1 237 ? 99.695  73.997  103.878 1.00 102.30 ? 218 HIS A ND1 1 
ATOM   1346 C CD2 . HIS A 1 237 ? 97.564  74.458  103.995 1.00 102.30 ? 218 HIS A CD2 1 
ATOM   1347 C CE1 . HIS A 1 237 ? 99.286  73.645  105.083 1.00 102.30 ? 218 HIS A CE1 1 
ATOM   1348 N NE2 . HIS A 1 237 ? 97.997  73.915  105.180 1.00 102.30 ? 218 HIS A NE2 1 
ATOM   1349 N N   . SER A 1 238 ? 100.303 75.259  99.182  1.00 98.39  ? 219 SER A N   1 
ATOM   1350 C CA  . SER A 1 238 ? 100.625 75.944  97.923  1.00 98.39  ? 219 SER A CA  1 
ATOM   1351 C C   . SER A 1 238 ? 99.364  76.455  97.227  1.00 98.39  ? 219 SER A C   1 
ATOM   1352 O O   . SER A 1 238 ? 99.097  76.158  96.061  1.00 98.39  ? 219 SER A O   1 
ATOM   1353 C CB  . SER A 1 238 ? 101.425 75.030  96.997  1.00 98.39  ? 219 SER A CB  1 
ATOM   1354 O OG  . SER A 1 238 ? 100.566 74.232  96.203  1.00 98.39  ? 219 SER A OG  1 
ATOM   1355 N N   . GLU A 1 239 ? 98.575  77.237  97.964  1.00 91.15  ? 220 GLU A N   1 
ATOM   1356 C CA  . GLU A 1 239 ? 97.176  77.440  97.604  1.00 91.15  ? 220 GLU A CA  1 
ATOM   1357 C C   . GLU A 1 239 ? 96.948  78.668  96.727  1.00 91.15  ? 220 GLU A C   1 
ATOM   1358 O O   . GLU A 1 239 ? 96.150  78.613  95.786  1.00 91.15  ? 220 GLU A O   1 
ATOM   1359 C CB  . GLU A 1 239 ? 96.325  77.525  98.877  1.00 91.15  ? 220 GLU A CB  1 
ATOM   1360 C CG  . GLU A 1 239 ? 96.720  78.619  99.866  1.00 91.15  ? 220 GLU A CG  1 
ATOM   1361 C CD  . GLU A 1 239 ? 97.938  78.277  100.711 1.00 91.15  ? 220 GLU A CD  1 
ATOM   1362 O OE1 . GLU A 1 239 ? 98.901  77.686  100.180 1.00 91.15  ? 220 GLU A OE1 1 
ATOM   1363 O OE2 . GLU A 1 239 ? 97.927  78.598  101.918 1.00 91.15  ? 220 GLU A OE2 1 
ATOM   1364 N N   . HIS A 1 240 ? 97.624  79.783  97.011  1.00 82.97  ? 221 HIS A N   1 
ATOM   1365 C CA  . HIS A 1 240 ? 97.461  80.964  96.172  1.00 82.97  ? 221 HIS A CA  1 
ATOM   1366 C C   . HIS A 1 240 ? 98.453  81.009  95.020  1.00 82.97  ? 221 HIS A C   1 
ATOM   1367 O O   . HIS A 1 240 ? 98.206  81.713  94.036  1.00 82.97  ? 221 HIS A O   1 
ATOM   1368 C CB  . HIS A 1 240 ? 97.599  82.245  96.996  1.00 82.97  ? 221 HIS A CB  1 
ATOM   1369 C CG  . HIS A 1 240 ? 96.812  82.243  98.268  1.00 82.97  ? 221 HIS A CG  1 
ATOM   1370 N ND1 . HIS A 1 240 ? 97.332  81.800  99.465  1.00 82.97  ? 221 HIS A ND1 1 
ATOM   1371 C CD2 . HIS A 1 240 ? 95.545  82.638  98.531  1.00 82.97  ? 221 HIS A CD2 1 
ATOM   1372 C CE1 . HIS A 1 240 ? 96.418  81.921  100.410 1.00 82.97  ? 221 HIS A CE1 1 
ATOM   1373 N NE2 . HIS A 1 240 ? 95.323  82.425  99.870  1.00 82.97  ? 221 HIS A NE2 1 
ATOM   1374 N N   . PHE A 1 241 ? 99.566  80.288  95.121  1.00 80.65  ? 222 PHE A N   1 
ATOM   1375 C CA  . PHE A 1 241 ? 100.588 80.292  94.077  1.00 80.65  ? 222 PHE A CA  1 
ATOM   1376 C C   . PHE A 1 241 ? 100.369 79.132  93.104  1.00 80.65  ? 222 PHE A C   1 
ATOM   1377 O O   . PHE A 1 241 ? 101.251 78.313  92.851  1.00 80.65  ? 222 PHE A O   1 
ATOM   1378 C CB  . PHE A 1 241 ? 101.976 80.238  94.701  1.00 80.65  ? 222 PHE A CB  1 
ATOM   1379 C CG  . PHE A 1 241 ? 102.433 81.547  95.274  1.00 80.65  ? 222 PHE A CG  1 
ATOM   1380 C CD1 . PHE A 1 241 ? 102.757 82.605  94.445  1.00 80.65  ? 222 PHE A CD1 1 
ATOM   1381 C CD2 . PHE A 1 241 ? 102.538 81.719  96.642  1.00 80.65  ? 222 PHE A CD2 1 
ATOM   1382 C CE1 . PHE A 1 241 ? 103.175 83.806  94.968  1.00 80.65  ? 222 PHE A CE1 1 
ATOM   1383 C CE2 . PHE A 1 241 ? 102.955 82.917  97.169  1.00 80.65  ? 222 PHE A CE2 1 
ATOM   1384 C CZ  . PHE A 1 241 ? 103.274 83.962  96.332  1.00 80.65  ? 222 PHE A CZ  1 
ATOM   1385 N N   . GLN A 1 242 ? 99.160  79.073  92.555  1.00 91.99  ? 223 GLN A N   1 
ATOM   1386 C CA  . GLN A 1 242 ? 98.811  78.049  91.581  1.00 91.99  ? 223 GLN A CA  1 
ATOM   1387 C C   . GLN A 1 242 ? 98.482  78.605  90.205  1.00 91.99  ? 223 GLN A C   1 
ATOM   1388 O O   . GLN A 1 242 ? 98.823  77.969  89.206  1.00 91.99  ? 223 GLN A O   1 
ATOM   1389 C CB  . GLN A 1 242 ? 97.631  77.201  92.095  1.00 91.99  ? 223 GLN A CB  1 
ATOM   1390 C CG  . GLN A 1 242 ? 96.271  77.893  92.107  1.00 91.99  ? 223 GLN A CG  1 
ATOM   1391 C CD  . GLN A 1 242 ? 95.498  77.707  90.814  1.00 91.99  ? 223 GLN A CD  1 
ATOM   1392 O OE1 . GLN A 1 242 ? 95.957  77.030  89.894  1.00 91.99  ? 223 GLN A OE1 1 
ATOM   1393 N NE2 . GLN A 1 242 ? 94.317  78.309  90.739  1.00 91.99  ? 223 GLN A NE2 1 
ATOM   1394 N N   . ASP A 1 243 ? 97.835  79.763  90.124  1.00 94.74  ? 224 ASP A N   1 
ATOM   1395 C CA  . ASP A 1 243 ? 97.563  80.426  88.854  1.00 94.74  ? 224 ASP A CA  1 
ATOM   1396 C C   . ASP A 1 243 ? 97.850  81.915  88.988  1.00 94.74  ? 224 ASP A C   1 
ATOM   1397 O O   . ASP A 1 243 ? 97.016  82.766  88.677  1.00 94.74  ? 224 ASP A O   1 
ATOM   1398 C CB  . ASP A 1 243 ? 96.131  80.184  88.384  1.00 94.74  ? 224 ASP A CB  1 
ATOM   1399 C CG  . ASP A 1 243 ? 95.909  80.639  86.953  1.00 94.74  ? 224 ASP A CG  1 
ATOM   1400 O OD1 . ASP A 1 243 ? 96.503  80.032  86.036  1.00 94.74  ? 224 ASP A OD1 1 
ATOM   1401 O OD2 . ASP A 1 243 ? 95.148  81.606  86.748  1.00 94.74  ? 224 ASP A OD2 1 
ATOM   1402 N N   . ALA A 1 244 ? 99.039  82.241  89.488  1.00 92.34  ? 225 ALA A N   1 
ATOM   1403 C CA  . ALA A 1 244 ? 99.439  83.629  89.636  1.00 92.34  ? 225 ALA A CA  1 
ATOM   1404 C C   . ALA A 1 244 ? 99.415  84.341  88.283  1.00 92.34  ? 225 ALA A C   1 
ATOM   1405 O O   . ALA A 1 244 ? 99.268  83.726  87.224  1.00 92.34  ? 225 ALA A O   1 
ATOM   1406 C CB  . ALA A 1 244 ? 100.828 83.721  90.262  1.00 92.34  ? 225 ALA A CB  1 
ATOM   1407 N N   . PHE A 1 245 ? 99.548  85.666  88.341  1.00 91.06  ? 226 PHE A N   1 
ATOM   1408 C CA  . PHE A 1 245 ? 99.512  86.599  87.218  1.00 91.06  ? 226 PHE A CA  1 
ATOM   1409 C C   . PHE A 1 245 ? 98.104  86.825  86.682  1.00 91.06  ? 226 PHE A C   1 
ATOM   1410 O O   . PHE A 1 245 ? 97.929  87.669  85.796  1.00 91.06  ? 226 PHE A O   1 
ATOM   1411 C CB  . PHE A 1 245 ? 100.410 86.173  86.045  1.00 91.06  ? 226 PHE A CB  1 
ATOM   1412 C CG  . PHE A 1 245 ? 101.880 86.182  86.360  1.00 91.06  ? 226 PHE A CG  1 
ATOM   1413 C CD1 . PHE A 1 245 ? 102.428 85.249  87.223  1.00 91.06  ? 226 PHE A CD1 1 
ATOM   1414 C CD2 . PHE A 1 245 ? 102.718 87.109  85.767  1.00 91.06  ? 226 PHE A CD2 1 
ATOM   1415 C CE1 . PHE A 1 245 ? 103.779 85.252  87.504  1.00 91.06  ? 226 PHE A CE1 1 
ATOM   1416 C CE2 . PHE A 1 245 ? 104.069 87.118  86.047  1.00 91.06  ? 226 PHE A CE2 1 
ATOM   1417 C CZ  . PHE A 1 245 ? 104.599 86.188  86.916  1.00 91.06  ? 226 PHE A CZ  1 
ATOM   1418 N N   . GLU A 1 246 ? 97.095  86.116  87.185  1.00 94.65  ? 227 GLU A N   1 
ATOM   1419 C CA  . GLU A 1 246 ? 95.737  86.307  86.696  1.00 94.65  ? 227 GLU A CA  1 
ATOM   1420 C C   . GLU A 1 246 ? 95.147  87.587  87.265  1.00 94.65  ? 227 GLU A C   1 
ATOM   1421 O O   . GLU A 1 246 ? 95.501  88.018  88.366  1.00 94.65  ? 227 GLU A O   1 
ATOM   1422 C CB  . GLU A 1 246 ? 94.841  85.124  87.063  1.00 94.65  ? 227 GLU A CB  1 
ATOM   1423 C CG  . GLU A 1 246 ? 94.555  84.988  88.545  1.00 94.65  ? 227 GLU A CG  1 
ATOM   1424 C CD  . GLU A 1 246 ? 93.584  83.864  88.846  1.00 94.65  ? 227 GLU A CD  1 
ATOM   1425 O OE1 . GLU A 1 246 ? 93.142  83.190  87.892  1.00 94.65  ? 227 GLU A OE1 1 
ATOM   1426 O OE2 . GLU A 1 246 ? 93.255  83.661  90.034  1.00 94.65  ? 227 GLU A OE2 1 
ATOM   1427 N N   . GLY A 1 247 ? 94.244  88.199  86.503  1.00 93.44  ? 228 GLY A N   1 
ATOM   1428 C CA  . GLY A 1 247 ? 93.612  89.431  86.918  1.00 93.44  ? 228 GLY A CA  1 
ATOM   1429 C C   . GLY A 1 247 ? 94.530  90.627  87.016  1.00 93.44  ? 228 GLY A C   1 
ATOM   1430 O O   . GLY A 1 247 ? 94.066  91.711  87.388  1.00 93.44  ? 228 GLY A O   1 
ATOM   1431 N N   . SER A 1 248 ? 95.812  90.471  86.696  1.00 91.16  ? 229 SER A N   1 
ATOM   1432 C CA  . SER A 1 248 ? 96.755  91.570  86.794  1.00 91.16  ? 229 SER A CA  1 
ATOM   1433 C C   . SER A 1 248 ? 96.436  92.642  85.759  1.00 91.16  ? 229 SER A C   1 
ATOM   1434 O O   . SER A 1 248 ? 95.609  92.461  84.861  1.00 91.16  ? 229 SER A O   1 
ATOM   1435 C CB  . SER A 1 248 ? 98.184  91.064  86.613  1.00 91.16  ? 229 SER A CB  1 
ATOM   1436 O OG  . SER A 1 248 ? 98.516  90.973  85.241  1.00 91.16  ? 229 SER A OG  1 
ATOM   1437 N N   . SER A 1 249 ? 97.110  93.777  85.897  1.00 95.91  ? 230 SER A N   1 
ATOM   1438 C CA  . SER A 1 249 ? 96.959  94.899  84.981  1.00 95.91  ? 230 SER A CA  1 
ATOM   1439 C C   . SER A 1 249 ? 98.312  95.191  84.350  1.00 95.91  ? 230 SER A C   1 
ATOM   1440 O O   . SER A 1 249 ? 99.247  95.608  85.042  1.00 95.91  ? 230 SER A O   1 
ATOM   1441 C CB  . SER A 1 249 ? 96.419  96.131  85.705  1.00 95.91  ? 230 SER A CB  1 
ATOM   1442 O OG  . SER A 1 249 ? 96.690  97.310  84.968  1.00 95.91  ? 230 SER A OG  1 
ATOM   1443 N N   . TRP A 1 250 ? 98.413  94.972  83.043  1.00 98.50  ? 231 TRP A N   1 
ATOM   1444 C CA  . TRP A 1 250 ? 99.640  95.218  82.302  1.00 98.50  ? 231 TRP A CA  1 
ATOM   1445 C C   . TRP A 1 250 ? 99.636  96.574  81.613  1.00 98.50  ? 231 TRP A C   1 
ATOM   1446 O O   . TRP A 1 250 ? 100.594 96.904  80.908  1.00 98.50  ? 231 TRP A O   1 
ATOM   1447 C CB  . TRP A 1 250 ? 99.866  94.106  81.277  1.00 98.50  ? 231 TRP A CB  1 
ATOM   1448 C CG  . TRP A 1 250 ? 99.870  92.737  81.879  1.00 98.50  ? 231 TRP A CG  1 
ATOM   1449 C CD1 . TRP A 1 250 ? 100.744 92.254  82.806  1.00 98.50  ? 231 TRP A CD1 1 
ATOM   1450 C CD2 . TRP A 1 250 ? 98.953  91.673  81.599  1.00 98.50  ? 231 TRP A CD2 1 
ATOM   1451 N NE1 . TRP A 1 250 ? 100.431 90.955  83.120  1.00 98.50  ? 231 TRP A NE1 1 
ATOM   1452 C CE2 . TRP A 1 250 ? 99.336  90.574  82.392  1.00 98.50  ? 231 TRP A CE2 1 
ATOM   1453 C CE3 . TRP A 1 250 ? 97.848  91.542  80.753  1.00 98.50  ? 231 TRP A CE3 1 
ATOM   1454 C CZ2 . TRP A 1 250 ? 98.651  89.361  82.367  1.00 98.50  ? 231 TRP A CZ2 1 
ATOM   1455 C CZ3 . TRP A 1 250 ? 97.169  90.337  80.729  1.00 98.50  ? 231 TRP A CZ3 1 
ATOM   1456 C CH2 . TRP A 1 250 ? 97.573  89.263  81.530  1.00 98.50  ? 231 TRP A CH2 1 
ATOM   1457 N N   . ASP A 1 251 ? 98.585  97.365  81.805  1.00 97.54  ? 232 ASP A N   1 
ATOM   1458 C CA  . ASP A 1 251 ? 98.528  98.705  81.241  1.00 97.54  ? 232 ASP A CA  1 
ATOM   1459 C C   . ASP A 1 251 ? 99.381  99.643  82.083  1.00 97.54  ? 232 ASP A C   1 
ATOM   1460 O O   . ASP A 1 251 ? 99.275  99.652  83.314  1.00 97.54  ? 232 ASP A O   1 
ATOM   1461 C CB  . ASP A 1 251 ? 97.083  99.197  81.179  1.00 97.54  ? 232 ASP A CB  1 
ATOM   1462 C CG  . ASP A 1 251 ? 96.302  98.567  80.039  1.00 97.54  ? 232 ASP A CG  1 
ATOM   1463 O OD1 . ASP A 1 251 ? 96.787  98.607  78.889  1.00 97.54  ? 232 ASP A OD1 1 
ATOM   1464 O OD2 . ASP A 1 251 ? 95.203  98.031  80.294  1.00 97.54  ? 232 ASP A OD2 1 
ATOM   1465 N N   . MET A 1 252 ? 100.230 100.429 81.412  1.00 92.15  ? 233 MET A N   1 
ATOM   1466 C CA  . MET A 1 252 ? 101.247 101.223 82.099  1.00 92.15  ? 233 MET A CA  1 
ATOM   1467 C C   . MET A 1 252 ? 100.666 102.075 83.219  1.00 92.15  ? 233 MET A C   1 
ATOM   1468 O O   . MET A 1 252 ? 101.356 102.345 84.208  1.00 92.15  ? 233 MET A O   1 
ATOM   1469 C CB  . MET A 1 252 ? 101.982 102.110 81.097  1.00 92.15  ? 233 MET A CB  1 
ATOM   1470 C CG  . MET A 1 252 ? 102.945 101.358 80.199  1.00 92.15  ? 233 MET A CG  1 
ATOM   1471 S SD  . MET A 1 252 ? 104.150 100.384 81.118  1.00 92.15  ? 233 MET A SD  1 
ATOM   1472 C CE  . MET A 1 252 ? 103.594 98.722  80.753  1.00 92.15  ? 233 MET A CE  1 
ATOM   1473 N N   . GLY A 1 253 ? 99.406  102.495 83.097  1.00 86.30  ? 234 GLY A N   1 
ATOM   1474 C CA  . GLY A 1 253 ? 98.777  103.295 84.136  1.00 86.30  ? 234 GLY A CA  1 
ATOM   1475 C C   . GLY A 1 253 ? 98.740  102.638 85.501  1.00 86.30  ? 234 GLY A C   1 
ATOM   1476 O O   . GLY A 1 253 ? 98.420  103.314 86.486  1.00 86.30  ? 234 GLY A O   1 
ATOM   1477 N N   . ASN A 1 254 ? 99.054  101.348 85.586  1.00 83.91  ? 235 ASN A N   1 
ATOM   1478 C CA  . ASN A 1 254 ? 99.131  100.635 86.853  1.00 83.91  ? 235 ASN A CA  1 
ATOM   1479 C C   . ASN A 1 254 ? 100.534 100.164 87.188  1.00 83.91  ? 235 ASN A C   1 
ATOM   1480 O O   . ASN A 1 254 ? 100.948 100.257 88.344  1.00 83.91  ? 235 ASN A O   1 
ATOM   1481 C CB  . ASN A 1 254 ? 98.184  99.434  86.843  1.00 83.91  ? 235 ASN A CB  1 
ATOM   1482 C CG  . ASN A 1 254 ? 96.739  99.836  87.042  1.00 83.91  ? 235 ASN A CG  1 
ATOM   1483 O OD1 . ASN A 1 254 ? 95.820  99.114  86.658  1.00 83.91  ? 235 ASN A OD1 1 
ATOM   1484 N ND2 . ASN A 1 254 ? 96.531  101.000 87.645  1.00 83.91  ? 235 ASN A ND2 1 
ATOM   1485 N N   . LEU A 1 255 ? 101.289 99.676  86.204  1.00 78.21  ? 236 LEU A N   1 
ATOM   1486 C CA  . LEU A 1 255 ? 102.657 99.255  86.478  1.00 78.21  ? 236 LEU A CA  1 
ATOM   1487 C C   . LEU A 1 255 ? 103.545 100.440 86.833  1.00 78.21  ? 236 LEU A C   1 
ATOM   1488 O O   . LEU A 1 255 ? 104.515 100.284 87.585  1.00 78.21  ? 236 LEU A O   1 
ATOM   1489 C CB  . LEU A 1 255 ? 103.223 98.501  85.278  1.00 78.21  ? 236 LEU A CB  1 
ATOM   1490 C CG  . LEU A 1 255 ? 102.850 97.021  85.208  1.00 78.21  ? 236 LEU A CG  1 
ATOM   1491 C CD1 . LEU A 1 255 ? 103.022 96.497  83.797  1.00 78.21  ? 236 LEU A CD1 1 
ATOM   1492 C CD2 . LEU A 1 255 ? 103.690 96.219  86.180  1.00 78.21  ? 236 LEU A CD2 1 
ATOM   1493 N N   . SER A 1 256 ? 103.225 101.628 86.320  1.00 76.57  ? 237 SER A N   1 
ATOM   1494 C CA  . SER A 1 256 ? 103.964 102.825 86.702  1.00 76.57  ? 237 SER A CA  1 
ATOM   1495 C C   . SER A 1 256 ? 103.905 103.037 88.207  1.00 76.57  ? 237 SER A C   1 
ATOM   1496 O O   . SER A 1 256 ? 104.939 103.084 88.881  1.00 76.57  ? 237 SER A O   1 
ATOM   1497 C CB  . SER A 1 256 ? 103.411 104.045 85.967  1.00 76.57  ? 237 SER A CB  1 
ATOM   1498 O OG  . SER A 1 256 ? 102.271 104.564 86.630  1.00 76.57  ? 237 SER A OG  1 
ATOM   1499 N N   . LEU A 1 257 ? 102.694 103.175 88.752  1.00 69.35  ? 238 LEU A N   1 
ATOM   1500 C CA  . LEU A 1 257 ? 102.554 103.352 90.192  1.00 69.35  ? 238 LEU A CA  1 
ATOM   1501 C C   . LEU A 1 257 ? 103.017 102.122 90.958  1.00 69.35  ? 238 LEU A C   1 
ATOM   1502 O O   . LEU A 1 257 ? 103.479 102.247 92.097  1.00 69.35  ? 238 LEU A O   1 
ATOM   1503 C CB  . LEU A 1 257 ? 101.109 103.689 90.543  1.00 69.35  ? 238 LEU A CB  1 
ATOM   1504 C CG  . LEU A 1 257 ? 100.581 104.979 89.921  1.00 69.35  ? 238 LEU A CG  1 
ATOM   1505 C CD1 . LEU A 1 257 ? 99.319  105.427 90.630  1.00 69.35  ? 238 LEU A CD1 1 
ATOM   1506 C CD2 . LEU A 1 257 ? 101.637 106.065 89.974  1.00 69.35  ? 238 LEU A CD2 1 
ATOM   1507 N N   . ALA A 1 258 ? 102.936 100.937 90.350  1.00 67.99  ? 239 ALA A N   1 
ATOM   1508 C CA  . ALA A 1 258 ? 103.484 99.749  90.990  1.00 67.99  ? 239 ALA A CA  1 
ATOM   1509 C C   . ALA A 1 258 ? 104.969 99.922  91.275  1.00 67.99  ? 239 ALA A C   1 
ATOM   1510 O O   . ALA A 1 258 ? 105.416 99.771  92.416  1.00 67.99  ? 239 ALA A O   1 
ATOM   1511 C CB  . ALA A 1 258 ? 103.241 98.520  90.117  1.00 67.99  ? 239 ALA A CB  1 
ATOM   1512 N N   . LEU A 1 259 ? 105.752 100.254 90.248  1.00 65.15  ? 240 LEU A N   1 
ATOM   1513 C CA  . LEU A 1 259 ? 107.181 100.465 90.465  1.00 65.15  ? 240 LEU A CA  1 
ATOM   1514 C C   . LEU A 1 259 ? 107.438 101.672 91.358  1.00 65.15  ? 240 LEU A C   1 
ATOM   1515 O O   . LEU A 1 259 ? 108.325 101.636 92.219  1.00 65.15  ? 240 LEU A O   1 
ATOM   1516 C CB  . LEU A 1 259 ? 107.910 100.619 89.133  1.00 65.15  ? 240 LEU A CB  1 
ATOM   1517 C CG  . LEU A 1 259 ? 108.565 99.342  88.605  1.00 65.15  ? 240 LEU A CG  1 
ATOM   1518 C CD1 . LEU A 1 259 ? 107.528 98.354  88.104  1.00 65.15  ? 240 LEU A CD1 1 
ATOM   1519 C CD2 . LEU A 1 259 ? 109.563 99.673  87.513  1.00 65.15  ? 240 LEU A CD2 1 
ATOM   1520 N N   . TYR A 1 260 ? 106.668 102.747 91.180  1.00 63.81  ? 241 TYR A N   1 
ATOM   1521 C CA  . TYR A 1 260 ? 106.916 103.961 91.950  1.00 63.81  ? 241 TYR A CA  1 
ATOM   1522 C C   . TYR A 1 260 ? 106.658 103.747 93.435  1.00 63.81  ? 241 TYR A C   1 
ATOM   1523 O O   . TYR A 1 260 ? 107.258 104.427 94.275  1.00 63.81  ? 241 TYR A O   1 
ATOM   1524 C CB  . TYR A 1 260 ? 106.059 105.108 91.423  1.00 63.81  ? 241 TYR A CB  1 
ATOM   1525 C CG  . TYR A 1 260 ? 105.923 106.250 92.398  1.00 63.81  ? 241 TYR A CG  1 
ATOM   1526 C CD1 . TYR A 1 260 ? 106.922 107.198 92.523  1.00 63.81  ? 241 TYR A CD1 1 
ATOM   1527 C CD2 . TYR A 1 260 ? 104.798 106.379 93.194  1.00 63.81  ? 241 TYR A CD2 1 
ATOM   1528 C CE1 . TYR A 1 260 ? 106.807 108.240 93.409  1.00 63.81  ? 241 TYR A CE1 1 
ATOM   1529 C CE2 . TYR A 1 260 ? 104.672 107.419 94.084  1.00 63.81  ? 241 TYR A CE2 1 
ATOM   1530 C CZ  . TYR A 1 260 ? 105.680 108.348 94.187  1.00 63.81  ? 241 TYR A CZ  1 
ATOM   1531 O OH  . TYR A 1 260 ? 105.559 109.392 95.074  1.00 63.81  ? 241 TYR A OH  1 
ATOM   1532 N N   . SER A 1 261 ? 105.769 102.818 93.785  1.00 63.00  ? 242 SER A N   1 
ATOM   1533 C CA  . SER A 1 261 ? 105.583 102.495 95.191  1.00 63.00  ? 242 SER A CA  1 
ATOM   1534 C C   . SER A 1 261 ? 106.404 101.288 95.612  1.00 63.00  ? 242 SER A C   1 
ATOM   1535 O O   . SER A 1 261 ? 106.465 100.979 96.805  1.00 63.00  ? 242 SER A O   1 
ATOM   1536 C CB  . SER A 1 261 ? 104.105 102.254 95.493  1.00 63.00  ? 242 SER A CB  1 
ATOM   1537 O OG  . SER A 1 261 ? 103.853 102.384 96.880  1.00 63.00  ? 242 SER A OG  1 
ATOM   1538 N N   . ALA A 1 262 ? 107.027 100.598 94.660  1.00 58.64  ? 243 ALA A N   1 
ATOM   1539 C CA  . ALA A 1 262 ? 108.041 99.618  95.011  1.00 58.64  ? 243 ALA A CA  1 
ATOM   1540 C C   . ALA A 1 262 ? 109.378 100.281 95.290  1.00 58.64  ? 243 ALA A C   1 
ATOM   1541 O O   . ALA A 1 262 ? 110.266 99.649  95.868  1.00 58.64  ? 243 ALA A O   1 
ATOM   1542 C CB  . ALA A 1 262 ? 108.195 98.587  93.896  1.00 58.64  ? 243 ALA A CB  1 
ATOM   1543 N N   . LEU A 1 263 ? 109.542 101.539 94.881  1.00 57.08  ? 244 LEU A N   1 
ATOM   1544 C CA  . LEU A 1 263 ? 110.748 102.295 95.200  1.00 57.08  ? 244 LEU A CA  1 
ATOM   1545 C C   . LEU A 1 263 ? 110.671 103.019 96.535  1.00 57.08  ? 244 LEU A C   1 
ATOM   1546 O O   . LEU A 1 263 ? 111.691 103.116 97.222  1.00 57.08  ? 244 LEU A O   1 
ATOM   1547 C CB  . LEU A 1 263 ? 111.064 103.310 94.098  1.00 57.08  ? 244 LEU A CB  1 
ATOM   1548 C CG  . LEU A 1 263 ? 112.030 102.846 93.009  1.00 57.08  ? 244 LEU A CG  1 
ATOM   1549 C CD1 . LEU A 1 263 ? 113.380 102.579 93.634  1.00 57.08  ? 244 LEU A CD1 1 
ATOM   1550 C CD2 . LEU A 1 263 ? 111.538 101.613 92.292  1.00 57.08  ? 244 LEU A CD2 1 
ATOM   1551 N N   . PHE A 1 264 ? 109.500 103.529 96.924  1.00 60.15  ? 245 PHE A N   1 
ATOM   1552 C CA  . PHE A 1 264 ? 109.382 104.136 98.246  1.00 60.15  ? 245 PHE A CA  1 
ATOM   1553 C C   . PHE A 1 264 ? 109.545 103.112 99.360  1.00 60.15  ? 245 PHE A C   1 
ATOM   1554 O O   . PHE A 1 264 ? 109.626 103.487 100.534 1.00 60.15  ? 245 PHE A O   1 
ATOM   1555 C CB  . PHE A 1 264 ? 108.043 104.845 98.401  1.00 60.15  ? 245 PHE A CB  1 
ATOM   1556 C CG  . PHE A 1 264 ? 108.046 106.249 97.906  1.00 60.15  ? 245 PHE A CG  1 
ATOM   1557 C CD1 . PHE A 1 264 ? 109.174 106.788 97.323  1.00 60.15  ? 245 PHE A CD1 1 
ATOM   1558 C CD2 . PHE A 1 264 ? 106.926 107.046 98.050  1.00 60.15  ? 245 PHE A CD2 1 
ATOM   1559 C CE1 . PHE A 1 264 ? 109.177 108.087 96.870  1.00 60.15  ? 245 PHE A CE1 1 
ATOM   1560 C CE2 . PHE A 1 264 ? 106.927 108.348 97.604  1.00 60.15  ? 245 PHE A CE2 1 
ATOM   1561 C CZ  . PHE A 1 264 ? 108.056 108.870 97.012  1.00 60.15  ? 245 PHE A CZ  1 
ATOM   1562 N N   . SER A 1 265 ? 109.573 101.826 99.022  1.00 52.61  ? 246 SER A N   1 
ATOM   1563 C CA  . SER A 1 265 ? 109.831 100.803 100.023 1.00 52.61  ? 246 SER A CA  1 
ATOM   1564 C C   . SER A 1 265 ? 111.310 100.480 100.145 1.00 52.61  ? 246 SER A C   1 
ATOM   1565 O O   . SER A 1 265 ? 111.722 99.904  101.156 1.00 52.61  ? 246 SER A O   1 
ATOM   1566 C CB  . SER A 1 265 ? 109.050 99.532  99.690  1.00 52.61  ? 246 SER A CB  1 
ATOM   1567 O OG  . SER A 1 265 ? 107.700 99.642  100.101 1.00 52.61  ? 246 SER A OG  1 
ATOM   1568 N N   . TYR A 1 266 ? 112.111 100.833 99.143  1.00 46.92  ? 247 TYR A N   1 
ATOM   1569 C CA  . TYR A 1 266 ? 113.549 100.617 99.182  1.00 46.92  ? 247 TYR A CA  1 
ATOM   1570 C C   . TYR A 1 266 ? 114.325 101.875 99.526  1.00 46.92  ? 247 TYR A C   1 
ATOM   1571 O O   . TYR A 1 266 ? 115.555 101.845 99.507  1.00 46.92  ? 247 TYR A O   1 
ATOM   1572 C CB  . TYR A 1 266 ? 114.051 100.085 97.840  1.00 46.92  ? 247 TYR A CB  1 
ATOM   1573 C CG  . TYR A 1 266 ? 113.781 98.627  97.589  1.00 46.92  ? 247 TYR A CG  1 
ATOM   1574 C CD1 . TYR A 1 266 ? 112.508 98.181  97.289  1.00 46.92  ? 247 TYR A CD1 1 
ATOM   1575 C CD2 . TYR A 1 266 ? 114.805 97.702  97.617  1.00 46.92  ? 247 TYR A CD2 1 
ATOM   1576 C CE1 . TYR A 1 266 ? 112.259 96.855  97.044  1.00 46.92  ? 247 TYR A CE1 1 
ATOM   1577 C CE2 . TYR A 1 266 ? 114.565 96.373  97.380  1.00 46.92  ? 247 TYR A CE2 1 
ATOM   1578 C CZ  . TYR A 1 266 ? 113.290 95.955  97.090  1.00 46.92  ? 247 TYR A CZ  1 
ATOM   1579 O OH  . TYR A 1 266 ? 113.047 94.627  96.848  1.00 46.92  ? 247 TYR A OH  1 
ATOM   1580 N N   . SER A 1 267 ? 113.630 102.962 99.834  1.00 51.03  ? 248 SER A N   1 
ATOM   1581 C CA  . SER A 1 267 ? 114.310 104.186 100.228 1.00 51.03  ? 248 SER A CA  1 
ATOM   1582 C C   . SER A 1 267 ? 115.134 103.953 101.487 1.00 51.03  ? 248 SER A C   1 
ATOM   1583 O O   . SER A 1 267 ? 114.716 103.211 102.377 1.00 51.03  ? 248 SER A O   1 
ATOM   1584 C CB  . SER A 1 267 ? 113.299 105.310 100.453 1.00 51.03  ? 248 SER A CB  1 
ATOM   1585 O OG  . SER A 1 267 ? 112.034 104.790 100.824 1.00 51.03  ? 248 SER A OG  1 
ATOM   1586 N N   . GLY A 1 268 ? 116.306 104.574 101.564 1.00 46.42  ? 249 GLY A N   1 
ATOM   1587 C CA  . GLY A 1 268 ? 117.143 104.432 102.743 1.00 46.42  ? 249 GLY A CA  1 
ATOM   1588 C C   . GLY A 1 268 ? 118.357 103.552 102.542 1.00 46.42  ? 249 GLY A C   1 
ATOM   1589 O O   . GLY A 1 268 ? 118.984 103.125 103.513 1.00 46.42  ? 249 GLY A O   1 
ATOM   1590 N N   . TRP A 1 269 ? 118.702 103.280 101.288 1.00 46.01  ? 250 TRP A N   1 
ATOM   1591 C CA  . TRP A 1 269 ? 119.835 102.405 101.001 1.00 46.01  ? 250 TRP A CA  1 
ATOM   1592 C C   . TRP A 1 269 ? 121.164 103.150 101.006 1.00 46.01  ? 250 TRP A C   1 
ATOM   1593 O O   . TRP A 1 269 ? 122.178 102.612 100.562 1.00 46.01  ? 250 TRP A O   1 
ATOM   1594 C CB  . TRP A 1 269 ? 119.639 101.696 99.658  1.00 46.01  ? 250 TRP A CB  1 
ATOM   1595 C CG  . TRP A 1 269 ? 119.199 102.583 98.542  1.00 46.01  ? 250 TRP A CG  1 
ATOM   1596 C CD1 . TRP A 1 269 ? 117.938 102.699 98.039  1.00 46.01  ? 250 TRP A CD1 1 
ATOM   1597 C CD2 . TRP A 1 269 ? 120.020 103.466 97.771  1.00 46.01  ? 250 TRP A CD2 1 
ATOM   1598 N NE1 . TRP A 1 269 ? 117.919 103.606 97.009  1.00 46.01  ? 250 TRP A NE1 1 
ATOM   1599 C CE2 . TRP A 1 269 ? 119.187 104.091 96.824  1.00 46.01  ? 250 TRP A CE2 1 
ATOM   1600 C CE3 . TRP A 1 269 ? 121.378 103.793 97.793  1.00 46.01  ? 250 TRP A CE3 1 
ATOM   1601 C CZ2 . TRP A 1 269 ? 119.666 105.023 95.909  1.00 46.01  ? 250 TRP A CZ2 1 
ATOM   1602 C CZ3 . TRP A 1 269 ? 121.850 104.715 96.885  1.00 46.01  ? 250 TRP A CZ3 1 
ATOM   1603 C CH2 . TRP A 1 269 ? 120.998 105.322 95.956  1.00 46.01  ? 250 TRP A CH2 1 
ATOM   1604 N N   . ASP A 1 270 ? 121.167 104.380 101.508 1.00 44.52  ? 251 ASP A N   1 
ATOM   1605 C CA  . ASP A 1 270 ? 122.389 105.178 101.508 1.00 44.52  ? 251 ASP A CA  1 
ATOM   1606 C C   . ASP A 1 270 ? 122.645 105.858 102.845 1.00 44.52  ? 251 ASP A C   1 
ATOM   1607 O O   . ASP A 1 270 ? 123.479 106.759 102.937 1.00 44.52  ? 251 ASP A O   1 
ATOM   1608 C CB  . ASP A 1 270 ? 122.324 106.230 100.405 1.00 44.52  ? 251 ASP A CB  1 
ATOM   1609 C CG  . ASP A 1 270 ? 121.441 107.400 100.774 1.00 44.52  ? 251 ASP A CG  1 
ATOM   1610 O OD1 . ASP A 1 270 ? 120.237 107.179 101.017 1.00 44.52  ? 251 ASP A OD1 1 
ATOM   1611 O OD2 . ASP A 1 270 ? 121.954 108.538 100.829 1.00 44.52  ? 251 ASP A OD2 1 
ATOM   1612 N N   . THR A 1 271 ? 121.926 105.444 103.881 1.00 37.46  ? 252 THR A N   1 
ATOM   1613 C CA  . THR A 1 271 ? 122.165 106.006 105.203 1.00 37.46  ? 252 THR A CA  1 
ATOM   1614 C C   . THR A 1 271 ? 123.651 105.896 105.507 1.00 37.46  ? 252 THR A C   1 
ATOM   1615 O O   . THR A 1 271 ? 124.229 106.775 106.148 1.00 37.46  ? 252 THR A O   1 
ATOM   1616 C CB  . THR A 1 271 ? 121.316 105.301 106.284 1.00 37.46  ? 252 THR A CB  1 
ATOM   1617 O OG1 . THR A 1 271 ? 120.514 106.270 106.970 1.00 37.46  ? 252 THR A OG1 1 
ATOM   1618 C CG2 . THR A 1 271 ? 122.189 104.571 107.296 1.00 37.46  ? 252 THR A CG2 1 
ATOM   1619 N N   . LEU A 1 272 ? 124.278 104.828 105.024 1.00 38.13  ? 253 LEU A N   1 
ATOM   1620 C CA  . LEU A 1 272 ? 125.704 104.633 105.255 1.00 38.13  ? 253 LEU A CA  1 
ATOM   1621 C C   . LEU A 1 272 ? 126.552 105.621 104.482 1.00 38.13  ? 253 LEU A C   1 
ATOM   1622 O O   . LEU A 1 272 ? 127.716 105.832 104.831 1.00 38.13  ? 253 LEU A O   1 
ATOM   1623 C CB  . LEU A 1 272 ? 126.117 103.227 104.858 1.00 38.13  ? 253 LEU A CB  1 
ATOM   1624 C CG  . LEU A 1 272 ? 127.550 102.801 105.130 1.00 38.13  ? 253 LEU A CG  1 
ATOM   1625 C CD1 . LEU A 1 272 ? 127.986 103.205 106.517 1.00 38.13  ? 253 LEU A CD1 1 
ATOM   1626 C CD2 . LEU A 1 272 ? 127.640 101.322 104.956 1.00 38.13  ? 253 LEU A CD2 1 
ATOM   1627 N N   . ASN A 1 273 ? 125.996 106.245 103.454 1.00 42.51  ? 254 ASN A N   1 
ATOM   1628 C CA  . ASN A 1 273 ? 126.754 107.239 102.722 1.00 42.51  ? 254 ASN A CA  1 
ATOM   1629 C C   . ASN A 1 273 ? 126.632 108.624 103.336 1.00 42.51  ? 254 ASN A C   1 
ATOM   1630 O O   . ASN A 1 273 ? 127.422 109.505 102.990 1.00 42.51  ? 254 ASN A O   1 
ATOM   1631 C CB  . ASN A 1 273 ? 126.303 107.250 101.267 1.00 42.51  ? 254 ASN A CB  1 
ATOM   1632 C CG  . ASN A 1 273 ? 127.360 107.784 100.344 1.00 42.51  ? 254 ASN A CG  1 
ATOM   1633 O OD1 . ASN A 1 273 ? 128.412 108.241 100.782 1.00 42.51  ? 254 ASN A OD1 1 
ATOM   1634 N ND2 . ASN A 1 273 ? 127.091 107.725 99.050  1.00 42.51  ? 254 ASN A ND2 1 
ATOM   1635 N N   . PHE A 1 274 ? 125.676 108.833 104.246 1.00 40.30  ? 255 PHE A N   1 
ATOM   1636 C CA  . PHE A 1 274 ? 125.615 110.081 104.999 1.00 40.30  ? 255 PHE A CA  1 
ATOM   1637 C C   . PHE A 1 274 ? 126.761 110.210 105.990 1.00 40.30  ? 255 PHE A C   1 
ATOM   1638 O O   . PHE A 1 274 ? 127.076 111.325 106.409 1.00 40.30  ? 255 PHE A O   1 
ATOM   1639 C CB  . PHE A 1 274 ? 124.294 110.185 105.760 1.00 40.30  ? 255 PHE A CB  1 
ATOM   1640 C CG  . PHE A 1 274 ? 123.171 110.787 104.968 1.00 40.30  ? 255 PHE A CG  1 
ATOM   1641 C CD1 . PHE A 1 274 ? 122.432 110.016 104.098 1.00 40.30  ? 255 PHE A CD1 1 
ATOM   1642 C CD2 . PHE A 1 274 ? 122.839 112.115 105.112 1.00 40.30  ? 255 PHE A CD2 1 
ATOM   1643 C CE1 . PHE A 1 274 ? 121.394 110.563 103.380 1.00 40.30  ? 255 PHE A CE1 1 
ATOM   1644 C CE2 . PHE A 1 274 ? 121.801 112.663 104.395 1.00 40.30  ? 255 PHE A CE2 1 
ATOM   1645 C CZ  . PHE A 1 274 ? 121.080 111.885 103.528 1.00 40.30  ? 255 PHE A CZ  1 
ATOM   1646 N N   . VAL A 1 275 ? 127.380 109.100 106.383 1.00 42.15  ? 256 VAL A N   1 
ATOM   1647 C CA  . VAL A 1 275 ? 128.446 109.120 107.376 1.00 42.15  ? 256 VAL A CA  1 
ATOM   1648 C C   . VAL A 1 275 ? 129.711 108.506 106.796 1.00 42.15  ? 256 VAL A C   1 
ATOM   1649 O O   . VAL A 1 275 ? 130.485 107.865 107.514 1.00 42.15  ? 256 VAL A O   1 
ATOM   1650 C CB  . VAL A 1 275 ? 128.016 108.397 108.663 1.00 42.15  ? 256 VAL A CB  1 
ATOM   1651 C CG1 . VAL A 1 275 ? 126.826 109.090 109.260 1.00 42.15  ? 256 VAL A CG1 1 
ATOM   1652 C CG2 . VAL A 1 275 ? 127.679 106.947 108.381 1.00 42.15  ? 256 VAL A CG2 1 
ATOM   1653 N N   . THR A 1 276 ? 129.928 108.698 105.493 1.00 48.16  ? 257 THR A N   1 
ATOM   1654 C CA  . THR A 1 276 ? 131.095 108.130 104.826 1.00 48.16  ? 257 THR A CA  1 
ATOM   1655 C C   . THR A 1 276 ? 132.394 108.445 105.555 1.00 48.16  ? 257 THR A C   1 
ATOM   1656 O O   . THR A 1 276 ? 133.316 107.625 105.561 1.00 48.16  ? 257 THR A O   1 
ATOM   1657 C CB  . THR A 1 276 ? 131.173 108.643 103.390 1.00 48.16  ? 257 THR A CB  1 
ATOM   1658 O OG1 . THR A 1 276 ? 129.957 108.330 102.705 1.00 48.16  ? 257 THR A OG1 1 
ATOM   1659 C CG2 . THR A 1 276 ? 132.329 108.000 102.654 1.00 48.16  ? 257 THR A CG2 1 
ATOM   1660 N N   . GLU A 1 277 ? 132.482 109.615 106.190 1.00 55.21  ? 258 GLU A N   1 
ATOM   1661 C CA  . GLU A 1 277 ? 133.751 110.046 106.768 1.00 55.21  ? 258 GLU A CA  1 
ATOM   1662 C C   . GLU A 1 277 ? 134.138 109.233 107.995 1.00 55.21  ? 258 GLU A C   1 
ATOM   1663 O O   . GLU A 1 277 ? 135.331 109.069 108.267 1.00 55.21  ? 258 GLU A O   1 
ATOM   1664 C CB  . GLU A 1 277 ? 133.685 111.527 107.127 1.00 55.21  ? 258 GLU A CB  1 
ATOM   1665 C CG  . GLU A 1 277 ? 135.018 112.238 107.095 1.00 55.21  ? 258 GLU A CG  1 
ATOM   1666 C CD  . GLU A 1 277 ? 134.872 113.730 107.296 1.00 55.21  ? 258 GLU A CD  1 
ATOM   1667 O OE1 . GLU A 1 277 ? 133.732 114.189 107.523 1.00 55.21  ? 258 GLU A OE1 1 
ATOM   1668 O OE2 . GLU A 1 277 ? 135.893 114.443 107.227 1.00 55.21  ? 258 GLU A OE2 1 
ATOM   1669 N N   . GLU A 1 278 ? 133.166 108.729 108.753 1.00 53.85  ? 259 GLU A N   1 
ATOM   1670 C CA  . GLU A 1 278 ? 133.451 107.992 109.976 1.00 53.85  ? 259 GLU A CA  1 
ATOM   1671 C C   . GLU A 1 278 ? 133.661 106.502 109.744 1.00 53.85  ? 259 GLU A C   1 
ATOM   1672 O O   . GLU A 1 278 ? 133.860 105.761 110.710 1.00 53.85  ? 259 GLU A O   1 
ATOM   1673 C CB  . GLU A 1 278 ? 132.333 108.192 110.996 1.00 53.85  ? 259 GLU A CB  1 
ATOM   1674 C CG  . GLU A 1 278 ? 131.719 109.568 111.003 1.00 53.85  ? 259 GLU A CG  1 
ATOM   1675 C CD  . GLU A 1 278 ? 130.623 109.689 112.037 1.00 53.85  ? 259 GLU A CD  1 
ATOM   1676 O OE1 . GLU A 1 278 ? 130.487 108.763 112.861 1.00 53.85  ? 259 GLU A OE1 1 
ATOM   1677 O OE2 . GLU A 1 278 ? 129.897 110.700 112.032 1.00 53.85  ? 259 GLU A OE2 1 
ATOM   1678 N N   . ILE A 1 279 ? 133.619 106.043 108.504 1.00 54.50  ? 260 ILE A N   1 
ATOM   1679 C CA  . ILE A 1 279 ? 133.771 104.621 108.227 1.00 54.50  ? 260 ILE A CA  1 
ATOM   1680 C C   . ILE A 1 279 ? 135.236 104.233 108.369 1.00 54.50  ? 260 ILE A C   1 
ATOM   1681 O O   . ILE A 1 279 ? 136.138 105.062 108.211 1.00 54.50  ? 260 ILE A O   1 
ATOM   1682 C CB  . ILE A 1 279 ? 133.215 104.287 106.831 1.00 54.50  ? 260 ILE A CB  1 
ATOM   1683 C CG1 . ILE A 1 279 ? 131.828 104.894 106.670 1.00 54.50  ? 260 ILE A CG1 1 
ATOM   1684 C CG2 . ILE A 1 279 ? 133.105 102.795 106.635 1.00 54.50  ? 260 ILE A CG2 1 
ATOM   1685 C CD1 . ILE A 1 279 ? 131.173 104.546 105.370 1.00 54.50  ? 260 ILE A CD1 1 
ATOM   1686 N N   . LYS A 1 280 ? 135.477 102.960 108.687 1.00 63.13  ? 261 LYS A N   1 
ATOM   1687 C CA  . LYS A 1 280 ? 136.835 102.484 108.929 1.00 63.13  ? 261 LYS A CA  1 
ATOM   1688 C C   . LYS A 1 280 ? 137.705 102.654 107.689 1.00 63.13  ? 261 LYS A C   1 
ATOM   1689 O O   . LYS A 1 280 ? 138.682 103.410 107.695 1.00 63.13  ? 261 LYS A O   1 
ATOM   1690 C CB  . LYS A 1 280 ? 136.796 101.020 109.366 1.00 63.13  ? 261 LYS A CB  1 
ATOM   1691 C CG  . LYS A 1 280 ? 138.135 100.446 109.782 1.00 63.13  ? 261 LYS A CG  1 
ATOM   1692 C CD  . LYS A 1 280 ? 138.647 101.109 111.046 1.00 63.13  ? 261 LYS A CD  1 
ATOM   1693 C CE  . LYS A 1 280 ? 137.751 100.783 112.228 1.00 63.13  ? 261 LYS A CE  1 
ATOM   1694 N NZ  . LYS A 1 280 ? 137.825 99.344  112.598 1.00 63.13  ? 261 LYS A NZ  1 
ATOM   1695 N N   . ASN A 1 281 ? 137.357 101.955 106.607 1.00 63.09  ? 262 ASN A N   1 
ATOM   1696 C CA  . ASN A 1 281 ? 138.038 102.066 105.318 1.00 63.09  ? 262 ASN A CA  1 
ATOM   1697 C C   . ASN A 1 281 ? 137.021 102.559 104.301 1.00 63.09  ? 262 ASN A C   1 
ATOM   1698 O O   . ASN A 1 281 ? 136.404 101.754 103.586 1.00 63.09  ? 262 ASN A O   1 
ATOM   1699 C CB  . ASN A 1 281 ? 138.641 100.732 104.886 1.00 63.09  ? 262 ASN A CB  1 
ATOM   1700 C CG  . ASN A 1 281 ? 139.858 100.356 105.693 1.00 63.09  ? 262 ASN A CG  1 
ATOM   1701 O OD1 . ASN A 1 281 ? 140.709 101.196 105.981 1.00 63.09  ? 262 ASN A OD1 1 
ATOM   1702 N ND2 . ASN A 1 281 ? 139.954 99.085  106.059 1.00 63.09  ? 262 ASN A ND2 1 
ATOM   1703 N N   . PRO A 1 282 ? 136.817 103.874 104.192 1.00 64.93  ? 263 PRO A N   1 
ATOM   1704 C CA  . PRO A 1 282 ? 135.734 104.386 103.338 1.00 64.93  ? 263 PRO A CA  1 
ATOM   1705 C C   . PRO A 1 282 ? 135.872 104.012 101.877 1.00 64.93  ? 263 PRO A C   1 
ATOM   1706 O O   . PRO A 1 282 ? 134.970 104.335 101.096 1.00 64.93  ? 263 PRO A O   1 
ATOM   1707 C CB  . PRO A 1 282 ? 135.818 105.907 103.524 1.00 64.93  ? 263 PRO A CB  1 
ATOM   1708 C CG  . PRO A 1 282 ? 136.729 106.126 104.691 1.00 64.93  ? 263 PRO A CG  1 
ATOM   1709 C CD  . PRO A 1 282 ? 137.642 104.953 104.749 1.00 64.93  ? 263 PRO A CD  1 
ATOM   1710 N N   . GLU A 1 283 ? 136.956 103.352 101.478 1.00 69.32  ? 264 GLU A N   1 
ATOM   1711 C CA  . GLU A 1 283 ? 137.124 102.951 100.088 1.00 69.32  ? 264 GLU A CA  1 
ATOM   1712 C C   . GLU A 1 283 ? 136.782 101.488 99.850  1.00 69.32  ? 264 GLU A C   1 
ATOM   1713 O O   . GLU A 1 283 ? 136.478 101.108 98.714  1.00 69.32  ? 264 GLU A O   1 
ATOM   1714 C CB  . GLU A 1 283 ? 138.558 103.231 99.632  1.00 69.32  ? 264 GLU A CB  1 
ATOM   1715 C CG  . GLU A 1 283 ? 138.854 104.709 99.452  1.00 69.32  ? 264 GLU A CG  1 
ATOM   1716 C CD  . GLU A 1 283 ? 140.279 104.972 99.022  1.00 69.32  ? 264 GLU A CD  1 
ATOM   1717 O OE1 . GLU A 1 283 ? 141.101 104.034 99.082  1.00 69.32  ? 264 GLU A OE1 1 
ATOM   1718 O OE2 . GLU A 1 283 ? 140.576 106.117 98.624  1.00 69.32  ? 264 GLU A OE2 1 
ATOM   1719 N N   . ARG A 1 284 ? 136.820 100.660 100.888 1.00 65.19  ? 265 ARG A N   1 
ATOM   1720 C CA  . ARG A 1 284 ? 136.458 99.254  100.778 1.00 65.19  ? 265 ARG A CA  1 
ATOM   1721 C C   . ARG A 1 284 ? 135.230 98.884  101.590 1.00 65.19  ? 265 ARG A C   1 
ATOM   1722 O O   . ARG A 1 284 ? 134.413 98.089  101.128 1.00 65.19  ? 265 ARG A O   1 
ATOM   1723 C CB  . ARG A 1 284 ? 137.635 98.370  101.207 1.00 65.19  ? 265 ARG A CB  1 
ATOM   1724 C CG  . ARG A 1 284 ? 137.243 96.996  101.720 1.00 65.19  ? 265 ARG A CG  1 
ATOM   1725 C CD  . ARG A 1 284 ? 138.466 96.189  102.111 1.00 65.19  ? 265 ARG A CD  1 
ATOM   1726 N NE  . ARG A 1 284 ? 138.111 94.986  102.855 1.00 65.19  ? 265 ARG A NE  1 
ATOM   1727 C CZ  . ARG A 1 284 ? 137.945 94.944  104.172 1.00 65.19  ? 265 ARG A CZ  1 
ATOM   1728 N NH1 . ARG A 1 284 ? 138.102 96.044  104.896 1.00 65.19  ? 265 ARG A NH1 1 
ATOM   1729 N NH2 . ARG A 1 284 ? 137.622 93.804  104.768 1.00 65.19  ? 265 ARG A NH2 1 
ATOM   1730 N N   . ASN A 1 285 ? 135.060 99.457  102.782 1.00 60.35  ? 266 ASN A N   1 
ATOM   1731 C CA  . ASN A 1 285 ? 133.938 99.077  103.629 1.00 60.35  ? 266 ASN A CA  1 
ATOM   1732 C C   . ASN A 1 285 ? 132.614 99.656  103.157 1.00 60.35  ? 266 ASN A C   1 
ATOM   1733 O O   . ASN A 1 285 ? 131.574 99.031  103.377 1.00 60.35  ? 266 ASN A O   1 
ATOM   1734 C CB  . ASN A 1 285 ? 134.194 99.498  105.075 1.00 60.35  ? 266 ASN A CB  1 
ATOM   1735 C CG  . ASN A 1 285 ? 135.318 98.714  105.716 1.00 60.35  ? 266 ASN A CG  1 
ATOM   1736 O OD1 . ASN A 1 285 ? 136.035 99.222  106.576 1.00 60.35  ? 266 ASN A OD1 1 
ATOM   1737 N ND2 . ASN A 1 285 ? 135.477 97.466  105.298 1.00 60.35  ? 266 ASN A ND2 1 
ATOM   1738 N N   . LEU A 1 286 ? 132.620 100.803 102.493 1.00 50.52  ? 267 LEU A N   1 
ATOM   1739 C CA  . LEU A 1 286 ? 131.366 101.386 102.030 1.00 50.52  ? 267 LEU A CA  1 
ATOM   1740 C C   . LEU A 1 286 ? 130.755 100.585 100.882 1.00 50.52  ? 267 LEU A C   1 
ATOM   1741 O O   . LEU A 1 286 ? 129.591 100.174 100.986 1.00 50.52  ? 267 LEU A O   1 
ATOM   1742 C CB  . LEU A 1 286 ? 131.564 102.842 101.617 1.00 50.52  ? 267 LEU A CB  1 
ATOM   1743 C CG  . LEU A 1 286 ? 130.361 103.465 100.924 1.00 50.52  ? 267 LEU A CG  1 
ATOM   1744 C CD1 . LEU A 1 286 ? 129.158 103.413 101.825 1.00 50.52  ? 267 LEU A CD1 1 
ATOM   1745 C CD2 . LEU A 1 286 ? 130.677 104.888 100.554 1.00 50.52  ? 267 LEU A CD2 1 
ATOM   1746 N N   . PRO A 1 287 ? 131.469 100.340 99.776  1.00 52.65  ? 268 PRO A N   1 
ATOM   1747 C CA  . PRO A 1 287 ? 130.833 99.592  98.684  1.00 52.65  ? 268 PRO A CA  1 
ATOM   1748 C C   . PRO A 1 287 ? 130.601 98.141  99.032  1.00 52.65  ? 268 PRO A C   1 
ATOM   1749 O O   . PRO A 1 287 ? 129.581 97.577  98.624  1.00 52.65  ? 268 PRO A O   1 
ATOM   1750 C CB  . PRO A 1 287 ? 131.819 99.740  97.517  1.00 52.65  ? 268 PRO A CB  1 
ATOM   1751 C CG  . PRO A 1 287 ? 132.888 100.648 97.998  1.00 52.65  ? 268 PRO A CG  1 
ATOM   1752 C CD  . PRO A 1 287 ? 132.888 100.581 99.476  1.00 52.65  ? 268 PRO A CD  1 
ATOM   1753 N N   . LEU A 1 288 ? 131.502 97.520  99.793  1.00 49.49  ? 269 LEU A N   1 
ATOM   1754 C CA  . LEU A 1 288 ? 131.254 96.156  100.241 1.00 49.49  ? 269 LEU A CA  1 
ATOM   1755 C C   . LEU A 1 288 ? 130.061 96.102  101.185 1.00 49.49  ? 269 LEU A C   1 
ATOM   1756 O O   . LEU A 1 288 ? 129.278 95.150  101.147 1.00 49.49  ? 269 LEU A O   1 
ATOM   1757 C CB  . LEU A 1 288 ? 132.498 95.583  100.913 1.00 49.49  ? 269 LEU A CB  1 
ATOM   1758 C CG  . LEU A 1 288 ? 132.314 94.269  101.667 1.00 49.49  ? 269 LEU A CG  1 
ATOM   1759 C CD1 . LEU A 1 288 ? 131.871 93.172  100.721 1.00 49.49  ? 269 LEU A CD1 1 
ATOM   1760 C CD2 . LEU A 1 288 ? 133.599 93.884  102.371 1.00 49.49  ? 269 LEU A CD2 1 
ATOM   1761 N N   . ALA A 1 289 ? 129.879 97.132  102.014 1.00 45.88  ? 270 ALA A N   1 
ATOM   1762 C CA  . ALA A 1 289 ? 128.734 97.143  102.915 1.00 45.88  ? 270 ALA A CA  1 
ATOM   1763 C C   . ALA A 1 289 ? 127.433 97.312  102.146 1.00 45.88  ? 270 ALA A C   1 
ATOM   1764 O O   . ALA A 1 289 ? 126.439 96.643  102.443 1.00 45.88  ? 270 ALA A O   1 
ATOM   1765 C CB  . ALA A 1 289 ? 128.893 98.244  103.954 1.00 45.88  ? 270 ALA A CB  1 
ATOM   1766 N N   . ILE A 1 290 ? 127.423 98.181  101.137 1.00 46.52  ? 271 ILE A N   1 
ATOM   1767 C CA  . ILE A 1 290 ? 126.213 98.337  100.335 1.00 46.52  ? 271 ILE A CA  1 
ATOM   1768 C C   . ILE A 1 290 ? 125.932 97.070  99.530  1.00 46.52  ? 271 ILE A C   1 
ATOM   1769 O O   . ILE A 1 290 ? 124.772 96.671  99.360  1.00 46.52  ? 271 ILE A O   1 
ATOM   1770 C CB  . ILE A 1 290 ? 126.325 99.584  99.440  1.00 46.52  ? 271 ILE A CB  1 
ATOM   1771 C CG1 . ILE A 1 290 ? 125.883 100.823 100.219 1.00 46.52  ? 271 ILE A CG1 1 
ATOM   1772 C CG2 . ILE A 1 290 ? 125.507 99.426  98.180  1.00 46.52  ? 271 ILE A CG2 1 
ATOM   1773 C CD1 . ILE A 1 290 ? 126.102 102.113 99.487  1.00 46.52  ? 271 ILE A CD1 1 
ATOM   1774 N N   . GLY A 1 291 ? 126.982 96.397  99.051  1.00 48.21  ? 272 GLY A N   1 
ATOM   1775 C CA  . GLY A 1 291 ? 126.802 95.159  98.315  1.00 48.21  ? 272 GLY A CA  1 
ATOM   1776 C C   . GLY A 1 291 ? 126.445 93.964  99.170  1.00 48.21  ? 272 GLY A C   1 
ATOM   1777 O O   . GLY A 1 291 ? 125.961 92.962  98.639  1.00 48.21  ? 272 GLY A O   1 
ATOM   1778 N N   . ILE A 1 292 ? 126.712 94.029  100.471 1.00 45.07  ? 273 ILE A N   1 
ATOM   1779 C CA  . ILE A 1 292 ? 126.212 93.012  101.387 1.00 45.07  ? 273 ILE A CA  1 
ATOM   1780 C C   . ILE A 1 292 ? 124.800 93.348  101.861 1.00 45.07  ? 273 ILE A C   1 
ATOM   1781 O O   . ILE A 1 292 ? 124.034 92.446  102.214 1.00 45.07  ? 273 ILE A O   1 
ATOM   1782 C CB  . ILE A 1 292 ? 127.180 92.845  102.575 1.00 45.07  ? 273 ILE A CB  1 
ATOM   1783 C CG1 . ILE A 1 292 ? 128.540 92.342  102.094 1.00 45.07  ? 273 ILE A CG1 1 
ATOM   1784 C CG2 . ILE A 1 292 ? 126.630 91.885  103.613 1.00 45.07  ? 273 ILE A CG2 1 
ATOM   1785 C CD1 . ILE A 1 292 ? 128.542 90.896  101.668 1.00 45.07  ? 273 ILE A CD1 1 
ATOM   1786 N N   . SER A 1 293 ? 124.425 94.626  101.847 1.00 44.90  ? 274 SER A N   1 
ATOM   1787 C CA  . SER A 1 293 ? 123.092 95.001  102.301 1.00 44.90  ? 274 SER A CA  1 
ATOM   1788 C C   . SER A 1 293 ? 122.040 94.767  101.226 1.00 44.90  ? 274 SER A C   1 
ATOM   1789 O O   . SER A 1 293 ? 121.034 94.096  101.480 1.00 44.90  ? 274 SER A O   1 
ATOM   1790 C CB  . SER A 1 293 ? 123.072 96.459  102.740 1.00 44.90  ? 274 SER A CB  1 
ATOM   1791 O OG  . SER A 1 293 ? 121.747 96.947  102.716 1.00 44.90  ? 274 SER A OG  1 
ATOM   1792 N N   . MET A 1 294 ? 122.240 95.326  100.029 1.00 48.08  ? 275 MET A N   1 
ATOM   1793 C CA  . MET A 1 294 ? 121.218 95.269  98.981  1.00 48.08  ? 275 MET A CA  1 
ATOM   1794 C C   . MET A 1 294 ? 120.656 93.877  98.723  1.00 48.08  ? 275 MET A C   1 
ATOM   1795 O O   . MET A 1 294 ? 119.424 93.740  98.663  1.00 48.08  ? 275 MET A O   1 
ATOM   1796 C CB  . MET A 1 294 ? 121.767 95.857  97.675  1.00 48.08  ? 275 MET A CB  1 
ATOM   1797 C CG  . MET A 1 294 ? 122.056 97.328  97.728  1.00 48.08  ? 275 MET A CG  1 
ATOM   1798 S SD  . MET A 1 294 ? 120.608 98.268  98.211  1.00 48.08  ? 275 MET A SD  1 
ATOM   1799 C CE  . MET A 1 294 ? 121.088 98.682  99.877  1.00 48.08  ? 275 MET A CE  1 
ATOM   1800 N N   . PRO A 1 295 ? 121.460 92.822  98.554  1.00 45.99  ? 276 PRO A N   1 
ATOM   1801 C CA  . PRO A 1 295 ? 120.849 91.500  98.374  1.00 45.99  ? 276 PRO A CA  1 
ATOM   1802 C C   . PRO A 1 295 ? 120.063 91.050  99.584  1.00 45.99  ? 276 PRO A C   1 
ATOM   1803 O O   . PRO A 1 295 ? 119.011 90.425  99.426  1.00 45.99  ? 276 PRO A O   1 
ATOM   1804 C CB  . PRO A 1 295 ? 122.055 90.591  98.106  1.00 45.99  ? 276 PRO A CB  1 
ATOM   1805 C CG  . PRO A 1 295 ? 123.194 91.304  98.701  1.00 45.99  ? 276 PRO A CG  1 
ATOM   1806 C CD  . PRO A 1 295 ? 122.923 92.745  98.440  1.00 45.99  ? 276 PRO A CD  1 
ATOM   1807 N N   . ILE A 1 296 ? 120.519 91.378  100.792 1.00 45.70  ? 277 ILE A N   1 
ATOM   1808 C CA  . ILE A 1 296 ? 119.796 90.954  101.987 1.00 45.70  ? 277 ILE A CA  1 
ATOM   1809 C C   . ILE A 1 296 ? 118.423 91.611  102.032 1.00 45.70  ? 277 ILE A C   1 
ATOM   1810 O O   . ILE A 1 296 ? 117.408 90.946  102.264 1.00 45.70  ? 277 ILE A O   1 
ATOM   1811 C CB  . ILE A 1 296 ? 120.613 91.261  103.253 1.00 45.70  ? 277 ILE A CB  1 
ATOM   1812 C CG1 . ILE A 1 296 ? 121.695 90.201  103.451 1.00 45.70  ? 277 ILE A CG1 1 
ATOM   1813 C CG2 . ILE A 1 296 ? 119.711 91.319  104.460 1.00 45.70  ? 277 ILE A CG2 1 
ATOM   1814 C CD1 . ILE A 1 296 ? 122.604 90.474  104.618 1.00 45.70  ? 277 ILE A CD1 1 
ATOM   1815 N N   . VAL A 1 297 ? 118.361 92.913  101.754 1.00 43.76  ? 278 VAL A N   1 
ATOM   1816 C CA  . VAL A 1 297 ? 117.079 93.604  101.824 1.00 43.76  ? 278 VAL A CA  1 
ATOM   1817 C C   . VAL A 1 297 ? 116.166 93.167  100.688 1.00 43.76  ? 278 VAL A C   1 
ATOM   1818 O O   . VAL A 1 297 ? 114.965 92.962  100.890 1.00 43.76  ? 278 VAL A O   1 
ATOM   1819 C CB  . VAL A 1 297 ? 117.284 95.125  101.830 1.00 43.76  ? 278 VAL A CB  1 
ATOM   1820 C CG1 . VAL A 1 297 ? 115.962 95.821  101.627 1.00 43.76  ? 278 VAL A CG1 1 
ATOM   1821 C CG2 . VAL A 1 297 ? 117.896 95.552  103.135 1.00 43.76  ? 278 VAL A CG2 1 
ATOM   1822 N N   . THR A 1 298 ? 116.707 93.008  99.481  1.00 45.44  ? 279 THR A N   1 
ATOM   1823 C CA  . THR A 1 298 ? 115.868 92.576  98.367  1.00 45.44  ? 279 THR A CA  1 
ATOM   1824 C C   . THR A 1 298 ? 115.308 91.179  98.610  1.00 45.44  ? 279 THR A C   1 
ATOM   1825 O O   . THR A 1 298 ? 114.113 90.931  98.400  1.00 45.44  ? 279 THR A O   1 
ATOM   1826 C CB  . THR A 1 298 ? 116.656 92.627  97.060  1.00 45.44  ? 279 THR A CB  1 
ATOM   1827 O OG1 . THR A 1 298 ? 117.052 93.978  96.796  1.00 45.44  ? 279 THR A OG1 1 
ATOM   1828 C CG2 . THR A 1 298 ? 115.810 92.128  95.909  1.00 45.44  ? 279 THR A CG2 1 
ATOM   1829 N N   . LEU A 1 299 ? 116.154 90.249  99.061  1.00 44.86  ? 280 LEU A N   1 
ATOM   1830 C CA  . LEU A 1 299 ? 115.683 88.895  99.317  1.00 44.86  ? 280 LEU A CA  1 
ATOM   1831 C C   . LEU A 1 299 ? 114.679 88.869  100.456 1.00 44.86  ? 280 LEU A C   1 
ATOM   1832 O O   . LEU A 1 299 ? 113.691 88.130  100.398 1.00 44.86  ? 280 LEU A O   1 
ATOM   1833 C CB  . LEU A 1 299 ? 116.858 87.973  99.622  1.00 44.86  ? 280 LEU A CB  1 
ATOM   1834 C CG  . LEU A 1 299 ? 117.774 87.691  98.434  1.00 44.86  ? 280 LEU A CG  1 
ATOM   1835 C CD1 . LEU A 1 299 ? 118.785 86.612  98.781  1.00 44.86  ? 280 LEU A CD1 1 
ATOM   1836 C CD2 . LEU A 1 299 ? 116.960 87.302  97.212  1.00 44.86  ? 280 LEU A CD2 1 
ATOM   1837 N N   . ILE A 1 300 ? 114.890 89.687  101.489 1.00 45.90  ? 281 ILE A N   1 
ATOM   1838 C CA  . ILE A 1 300 ? 113.942 89.701  102.596 1.00 45.90  ? 281 ILE A CA  1 
ATOM   1839 C C   . ILE A 1 300 ? 112.612 90.297  102.158 1.00 45.90  ? 281 ILE A C   1 
ATOM   1840 O O   . ILE A 1 300 ? 111.551 89.806  102.545 1.00 45.90  ? 281 ILE A O   1 
ATOM   1841 C CB  . ILE A 1 300 ? 114.533 90.437  103.809 1.00 45.90  ? 281 ILE A CB  1 
ATOM   1842 C CG1 . ILE A 1 300 ? 115.609 89.578  104.467 1.00 45.90  ? 281 ILE A CG1 1 
ATOM   1843 C CG2 . ILE A 1 300 ? 113.464 90.773  104.802 1.00 45.90  ? 281 ILE A CG2 1 
ATOM   1844 C CD1 . ILE A 1 300 ? 116.366 90.289  105.547 1.00 45.90  ? 281 ILE A CD1 1 
ATOM   1845 N N   . TYR A 1 301 ? 112.636 91.316  101.298 1.00 47.52  ? 282 TYR A N   1 
ATOM   1846 C CA  . TYR A 1 301 ? 111.383 91.871  100.794 1.00 47.52  ? 282 TYR A CA  1 
ATOM   1847 C C   . TYR A 1 301 ? 110.622 90.843  99.965  1.00 47.52  ? 282 TYR A C   1 
ATOM   1848 O O   . TYR A 1 301 ? 109.431 90.591  100.201 1.00 47.52  ? 282 TYR A O   1 
ATOM   1849 C CB  . TYR A 1 301 ? 111.651 93.126  99.969  1.00 47.52  ? 282 TYR A CB  1 
ATOM   1850 C CG  . TYR A 1 301 ? 111.807 94.386  100.784 1.00 47.52  ? 282 TYR A CG  1 
ATOM   1851 C CD1 . TYR A 1 301 ? 111.368 94.449  102.092 1.00 47.52  ? 282 TYR A CD1 1 
ATOM   1852 C CD2 . TYR A 1 301 ? 112.381 95.518  100.237 1.00 47.52  ? 282 TYR A CD2 1 
ATOM   1853 C CE1 . TYR A 1 301 ? 111.507 95.601  102.830 1.00 47.52  ? 282 TYR A CE1 1 
ATOM   1854 C CE2 . TYR A 1 301 ? 112.522 96.671  100.968 1.00 47.52  ? 282 TYR A CE2 1 
ATOM   1855 C CZ  . TYR A 1 301 ? 112.084 96.708  102.261 1.00 47.52  ? 282 TYR A CZ  1 
ATOM   1856 O OH  . TYR A 1 301 ? 112.227 97.864  102.987 1.00 47.52  ? 282 TYR A OH  1 
ATOM   1857 N N   . ILE A 1 302 ? 111.299 90.233  98.989  1.00 46.62  ? 283 ILE A N   1 
ATOM   1858 C CA  . ILE A 1 302 ? 110.628 89.276  98.113  1.00 46.62  ? 283 ILE A CA  1 
ATOM   1859 C C   . ILE A 1 302 ? 110.089 88.100  98.916  1.00 46.62  ? 283 ILE A C   1 
ATOM   1860 O O   . ILE A 1 302 ? 108.937 87.689  98.743  1.00 46.62  ? 283 ILE A O   1 
ATOM   1861 C CB  . ILE A 1 302 ? 111.573 88.809  96.995  1.00 46.62  ? 283 ILE A CB  1 
ATOM   1862 C CG1 . ILE A 1 302 ? 111.772 89.918  95.971  1.00 46.62  ? 283 ILE A CG1 1 
ATOM   1863 C CG2 . ILE A 1 302 ? 111.009 87.592  96.306  1.00 46.62  ? 283 ILE A CG2 1 
ATOM   1864 C CD1 . ILE A 1 302 ? 112.753 89.559  94.889  1.00 46.62  ? 283 ILE A CD1 1 
ATOM   1865 N N   . LEU A 1 303 ? 110.899 87.549  99.823  1.00 49.61  ? 284 LEU A N   1 
ATOM   1866 C CA  . LEU A 1 303 ? 110.459 86.366  100.551 1.00 49.61  ? 284 LEU A CA  1 
ATOM   1867 C C   . LEU A 1 303 ? 109.416 86.697  101.614 1.00 49.61  ? 284 LEU A C   1 
ATOM   1868 O O   . LEU A 1 303 ? 108.531 85.876  101.880 1.00 49.61  ? 284 LEU A O   1 
ATOM   1869 C CB  . LEU A 1 303 ? 111.659 85.656  101.166 1.00 49.61  ? 284 LEU A CB  1 
ATOM   1870 C CG  . LEU A 1 303 ? 112.608 85.070  100.122 1.00 49.61  ? 284 LEU A CG  1 
ATOM   1871 C CD1 . LEU A 1 303 ? 113.839 84.478  100.776 1.00 49.61  ? 284 LEU A CD1 1 
ATOM   1872 C CD2 . LEU A 1 303 ? 111.894 84.030  99.289  1.00 49.61  ? 284 LEU A CD2 1 
ATOM   1873 N N   . THR A 1 304 ? 109.479 87.882  102.225 1.00 51.56  ? 285 THR A N   1 
ATOM   1874 C CA  . THR A 1 304 ? 108.423 88.286  103.144 1.00 51.56  ? 285 THR A CA  1 
ATOM   1875 C C   . THR A 1 304 ? 107.095 88.427  102.417 1.00 51.56  ? 285 THR A C   1 
ATOM   1876 O O   . THR A 1 304 ? 106.049 88.005  102.929 1.00 51.56  ? 285 THR A O   1 
ATOM   1877 C CB  . THR A 1 304 ? 108.804 89.592  103.835 1.00 51.56  ? 285 THR A CB  1 
ATOM   1878 O OG1 . THR A 1 304 ? 109.803 89.326  104.823 1.00 51.56  ? 285 THR A OG1 1 
ATOM   1879 C CG2 . THR A 1 304 ? 107.601 90.213  104.512 1.00 51.56  ? 285 THR A CG2 1 
ATOM   1880 N N   . ASN A 1 305 ? 107.106 89.012  101.217 1.00 52.88  ? 286 ASN A N   1 
ATOM   1881 C CA  . ASN A 1 305 ? 105.856 89.071  100.472 1.00 52.88  ? 286 ASN A CA  1 
ATOM   1882 C C   . ASN A 1 305 ? 105.424 87.694  99.987  1.00 52.88  ? 286 ASN A C   1 
ATOM   1883 O O   . ASN A 1 305 ? 104.222 87.437  99.863  1.00 52.88  ? 286 ASN A O   1 
ATOM   1884 C CB  . ASN A 1 305 ? 105.977 90.049  99.315  1.00 52.88  ? 286 ASN A CB  1 
ATOM   1885 C CG  . ASN A 1 305 ? 106.000 91.472  99.785  1.00 52.88  ? 286 ASN A CG  1 
ATOM   1886 O OD1 . ASN A 1 305 ? 106.678 91.800  100.755 1.00 52.88  ? 286 ASN A OD1 1 
ATOM   1887 N ND2 . ASN A 1 305 ? 105.230 92.324  99.130  1.00 52.88  ? 286 ASN A ND2 1 
ATOM   1888 N N   . VAL A 1 306 ? 106.374 86.791  99.738  1.00 56.02  ? 287 VAL A N   1 
ATOM   1889 C CA  . VAL A 1 306 ? 106.008 85.400  99.489  1.00 56.02  ? 287 VAL A CA  1 
ATOM   1890 C C   . VAL A 1 306 ? 105.246 84.841  100.680 1.00 56.02  ? 287 VAL A C   1 
ATOM   1891 O O   . VAL A 1 306 ? 104.206 84.192  100.522 1.00 56.02  ? 287 VAL A O   1 
ATOM   1892 C CB  . VAL A 1 306 ? 107.256 84.557  99.172  1.00 56.02  ? 287 VAL A CB  1 
ATOM   1893 C CG1 . VAL A 1 306 ? 106.961 83.083  99.364  1.00 56.02  ? 287 VAL A CG1 1 
ATOM   1894 C CG2 . VAL A 1 306 ? 107.715 84.808  97.756  1.00 56.02  ? 287 VAL A CG2 1 
ATOM   1895 N N   . ALA A 1 307 ? 105.736 85.106  101.889 1.00 56.85  ? 288 ALA A N   1 
ATOM   1896 C CA  . ALA A 1 307 ? 105.060 84.625  103.090 1.00 56.85  ? 288 ALA A CA  1 
ATOM   1897 C C   . ALA A 1 307 ? 103.648 85.191  103.192 1.00 56.85  ? 288 ALA A C   1 
ATOM   1898 O O   . ALA A 1 307 ? 102.675 84.443  103.363 1.00 56.85  ? 288 ALA A O   1 
ATOM   1899 C CB  . ALA A 1 307 ? 105.874 84.985  104.329 1.00 56.85  ? 288 ALA A CB  1 
ATOM   1900 N N   . TYR A 1 308 ? 103.522 86.519  103.100 1.00 56.01  ? 289 TYR A N   1 
ATOM   1901 C CA  . TYR A 1 308 ? 102.204 87.150  103.160 1.00 56.01  ? 289 TYR A CA  1 
ATOM   1902 C C   . TYR A 1 308 ? 101.252 86.529  102.149 1.00 56.01  ? 289 TYR A C   1 
ATOM   1903 O O   . TYR A 1 308 ? 100.176 86.040  102.509 1.00 56.01  ? 289 TYR A O   1 
ATOM   1904 C CB  . TYR A 1 308 ? 102.301 88.656  102.910 1.00 56.01  ? 289 TYR A CB  1 
ATOM   1905 C CG  . TYR A 1 308 ? 103.026 89.444  103.965 1.00 56.01  ? 289 TYR A CG  1 
ATOM   1906 C CD1 . TYR A 1 308 ? 103.313 88.893  105.196 1.00 56.01  ? 289 TYR A CD1 1 
ATOM   1907 C CD2 . TYR A 1 308 ? 103.418 90.749  103.727 1.00 56.01  ? 289 TYR A CD2 1 
ATOM   1908 C CE1 . TYR A 1 308 ? 103.978 89.616  106.158 1.00 56.01  ? 289 TYR A CE1 1 
ATOM   1909 C CE2 . TYR A 1 308 ? 104.082 91.478  104.681 1.00 56.01  ? 289 TYR A CE2 1 
ATOM   1910 C CZ  . TYR A 1 308 ? 104.359 90.907  105.895 1.00 56.01  ? 289 TYR A CZ  1 
ATOM   1911 O OH  . TYR A 1 308 ? 105.022 91.629  106.856 1.00 56.01  ? 289 TYR A OH  1 
ATOM   1912 N N   . TYR A 1 309 ? 101.635 86.536  100.873 1.00 65.71  ? 290 TYR A N   1 
ATOM   1913 C CA  . TYR A 1 309 ? 100.733 86.065  99.832  1.00 65.71  ? 290 TYR A CA  1 
ATOM   1914 C C   . TYR A 1 309 ? 100.479 84.567  99.915  1.00 65.71  ? 290 TYR A C   1 
ATOM   1915 O O   . TYR A 1 309 ? 99.476  84.094  99.371  1.00 65.71  ? 290 TYR A O   1 
ATOM   1916 C CB  . TYR A 1 309 ? 101.287 86.444  98.462  1.00 65.71  ? 290 TYR A CB  1 
ATOM   1917 C CG  . TYR A 1 309 ? 101.494 87.930  98.310  1.00 65.71  ? 290 TYR A CG  1 
ATOM   1918 C CD1 . TYR A 1 309 ? 100.730 88.830  99.035  1.00 65.71  ? 290 TYR A CD1 1 
ATOM   1919 C CD2 . TYR A 1 309 ? 102.456 88.433  97.452  1.00 65.71  ? 290 TYR A CD2 1 
ATOM   1920 C CE1 . TYR A 1 309 ? 100.915 90.186  98.907  1.00 65.71  ? 290 TYR A CE1 1 
ATOM   1921 C CE2 . TYR A 1 309 ? 102.649 89.790  97.318  1.00 65.71  ? 290 TYR A CE2 1 
ATOM   1922 C CZ  . TYR A 1 309 ? 101.875 90.662  98.047  1.00 65.71  ? 290 TYR A CZ  1 
ATOM   1923 O OH  . TYR A 1 309 ? 102.060 92.018  97.918  1.00 65.71  ? 290 TYR A OH  1 
ATOM   1924 N N   . THR A 1 310 ? 101.348 83.810  100.581 1.00 68.10  ? 291 THR A N   1 
ATOM   1925 C CA  . THR A 1 310 ? 101.052 82.402  100.795 1.00 68.10  ? 291 THR A CA  1 
ATOM   1926 C C   . THR A 1 310 ? 100.017 82.213  101.894 1.00 68.10  ? 291 THR A C   1 
ATOM   1927 O O   . THR A 1 310 ? 99.124  81.369  101.766 1.00 68.10  ? 291 THR A O   1 
ATOM   1928 C CB  . THR A 1 310 ? 102.330 81.637  101.132 1.00 68.10  ? 291 THR A CB  1 
ATOM   1929 O OG1 . THR A 1 310 ? 103.213 81.667  100.005 1.00 68.10  ? 291 THR A OG1 1 
ATOM   1930 C CG2 . THR A 1 310 ? 102.014 80.200  101.488 1.00 68.10  ? 291 THR A CG2 1 
ATOM   1931 N N   . VAL A 1 311 ? 100.100 82.993  102.966 1.00 65.89  ? 292 VAL A N   1 
ATOM   1932 C CA  . VAL A 1 311 ? 99.167  82.818  104.077 1.00 65.89  ? 292 VAL A CA  1 
ATOM   1933 C C   . VAL A 1 311 ? 97.901  83.641  103.881 1.00 65.89  ? 292 VAL A C   1 
ATOM   1934 O O   . VAL A 1 311 ? 96.788  83.133  104.037 1.00 65.89  ? 292 VAL A O   1 
ATOM   1935 C CB  . VAL A 1 311 ? 99.859  83.154  105.412 1.00 65.89  ? 292 VAL A CB  1 
ATOM   1936 C CG1 . VAL A 1 311 ? 98.827  83.469  106.471 1.00 65.89  ? 292 VAL A CG1 1 
ATOM   1937 C CG2 . VAL A 1 311 ? 100.726 81.995  105.850 1.00 65.89  ? 292 VAL A CG2 1 
ATOM   1938 N N   . LEU A 1 312 ? 98.073  84.922  103.582 1.00 68.62  ? 293 LEU A N   1 
ATOM   1939 C CA  . LEU A 1 312 ? 96.921  85.808  103.464 1.00 68.62  ? 293 LEU A CA  1 
ATOM   1940 C C   . LEU A 1 312 ? 96.493  86.034  102.028 1.00 68.62  ? 293 LEU A C   1 
ATOM   1941 O O   . LEU A 1 312 ? 97.173  85.611  101.092 1.00 68.62  ? 293 LEU A O   1 
ATOM   1942 C CB  . LEU A 1 312 ? 97.246  87.152  104.118 1.00 68.62  ? 293 LEU A CB  1 
ATOM   1943 C CG  . LEU A 1 312 ? 98.344  87.123  105.184 1.00 68.62  ? 293 LEU A CG  1 
ATOM   1944 C CD1 . LEU A 1 312 ? 99.213  88.369  105.106 1.00 68.62  ? 293 LEU A CD1 1 
ATOM   1945 C CD2 . LEU A 1 312 ? 97.734  86.977  106.569 1.00 68.62  ? 293 LEU A CD2 1 
ATOM   1946 N N   . ASN A 1 313 ? 95.362  86.706  101.856 1.00 73.57  ? 294 ASN A N   1 
ATOM   1947 C CA  . ASN A 1 313 ? 94.862  86.980  100.517 1.00 73.57  ? 294 ASN A CA  1 
ATOM   1948 C C   . ASN A 1 313 ? 95.074  88.439  100.149 1.00 73.57  ? 294 ASN A C   1 
ATOM   1949 O O   . ASN A 1 313 ? 94.994  89.320  101.002 1.00 73.57  ? 294 ASN A O   1 
ATOM   1950 C CB  . ASN A 1 313 ? 93.384  86.595  100.404 1.00 73.57  ? 294 ASN A CB  1 
ATOM   1951 C CG  . ASN A 1 313 ? 92.498  87.773  100.060 1.00 73.57  ? 294 ASN A CG  1 
ATOM   1952 O OD1 . ASN A 1 313 ? 92.071  88.518  100.939 1.00 73.57  ? 294 ASN A OD1 1 
ATOM   1953 N ND2 . ASN A 1 313 ? 92.213  87.942  98.774  1.00 73.57  ? 294 ASN A ND2 1 
ATOM   1954 N N   . ILE A 1 314 ? 95.344  88.695  98.876  1.00 71.31  ? 295 ILE A N   1 
ATOM   1955 C CA  . ILE A 1 314 ? 95.594  90.054  98.423  1.00 71.31  ? 295 ILE A CA  1 
ATOM   1956 C C   . ILE A 1 314 ? 94.589  91.026  99.017  1.00 71.31  ? 295 ILE A C   1 
ATOM   1957 O O   . ILE A 1 314 ? 94.970  92.060  99.550  1.00 71.31  ? 295 ILE A O   1 
ATOM   1958 C CB  . ILE A 1 314 ? 95.553  90.132  96.884  1.00 71.31  ? 295 ILE A CB  1 
ATOM   1959 C CG1 . ILE A 1 314 ? 95.016  91.487  96.419  1.00 71.31  ? 295 ILE A CG1 1 
ATOM   1960 C CG2 . ILE A 1 314 ? 94.710  88.999  96.318  1.00 71.31  ? 295 ILE A CG2 1 
ATOM   1961 C CD1 . ILE A 1 314 ? 95.100  91.689  94.925  1.00 71.31  ? 295 ILE A CD1 1 
ATOM   1962 N N   . SER A 1 315 ? 93.308  90.691  98.935  1.00 75.43  ? 296 SER A N   1 
ATOM   1963 C CA  . SER A 1 315 ? 92.277  91.584  99.443  1.00 75.43  ? 296 SER A CA  1 
ATOM   1964 C C   . SER A 1 315 ? 92.562  91.977  100.888 1.00 75.43  ? 296 SER A C   1 
ATOM   1965 O O   . SER A 1 315 ? 92.680  93.161  101.198 1.00 75.43  ? 296 SER A O   1 
ATOM   1966 C CB  . SER A 1 315 ? 90.891  90.943  99.314  1.00 75.43  ? 296 SER A CB  1 
ATOM   1967 O OG  . SER A 1 315 ? 90.385  90.531  100.571 1.00 75.43  ? 296 SER A OG  1 
ATOM   1968 N N   . ASP A 1 316 ? 92.673  90.991  101.772 1.00 72.90  ? 297 ASP A N   1 
ATOM   1969 C CA  . ASP A 1 316 ? 92.890  91.306  103.177 1.00 72.90  ? 297 ASP A CA  1 
ATOM   1970 C C   . ASP A 1 316 ? 94.207  92.045  103.325 1.00 72.90  ? 297 ASP A C   1 
ATOM   1971 O O   . ASP A 1 316 ? 94.282  93.033  104.043 1.00 72.90  ? 297 ASP A O   1 
ATOM   1972 C CB  . ASP A 1 316 ? 92.840  90.054  104.067 1.00 72.90  ? 297 ASP A CB  1 
ATOM   1973 C CG  . ASP A 1 316 ? 93.915  89.042  103.733 1.00 72.90  ? 297 ASP A CG  1 
ATOM   1974 O OD1 . ASP A 1 316 ? 95.112  89.338  103.930 1.00 72.90  ? 297 ASP A OD1 1 
ATOM   1975 O OD2 . ASP A 1 316 ? 93.558  87.932  103.296 1.00 72.90  ? 297 ASP A OD2 1 
ATOM   1976 N N   . VAL A 1 317 ? 95.242  91.580  102.638 1.00 68.49  ? 298 VAL A N   1 
ATOM   1977 C CA  . VAL A 1 317 ? 96.511  92.280  102.677 1.00 68.49  ? 298 VAL A CA  1 
ATOM   1978 C C   . VAL A 1 317 ? 96.244  93.727  102.340 1.00 68.49  ? 298 VAL A C   1 
ATOM   1979 O O   . VAL A 1 317 ? 96.539  94.617  103.135 1.00 68.49  ? 298 VAL A O   1 
ATOM   1980 C CB  . VAL A 1 317 ? 97.509  91.698  101.665 1.00 68.49  ? 298 VAL A CB  1 
ATOM   1981 C CG1 . VAL A 1 317 ? 98.733  92.593  101.549 1.00 68.49  ? 298 VAL A CG1 1 
ATOM   1982 C CG2 . VAL A 1 317 ? 97.902  90.282  102.058 1.00 68.49  ? 298 VAL A CG2 1 
ATOM   1983 N N   . LEU A 1 318 ? 95.669  93.957  101.165 1.00 73.96  ? 299 LEU A N   1 
ATOM   1984 C CA  . LEU A 1 318 ? 95.378  95.313  100.723 1.00 73.96  ? 299 LEU A CA  1 
ATOM   1985 C C   . LEU A 1 318 ? 94.526  96.076  101.721 1.00 73.96  ? 299 LEU A C   1 
ATOM   1986 O O   . LEU A 1 318 ? 94.456  97.302  101.672 1.00 73.96  ? 299 LEU A O   1 
ATOM   1987 C CB  . LEU A 1 318 ? 94.670  95.270  99.370  1.00 73.96  ? 299 LEU A CB  1 
ATOM   1988 C CG  . LEU A 1 318 ? 95.627  95.038  98.206  1.00 73.96  ? 299 LEU A CG  1 
ATOM   1989 C CD1 . LEU A 1 318 ? 94.910  95.153  96.871  1.00 73.96  ? 299 LEU A CD1 1 
ATOM   1990 C CD2 . LEU A 1 318 ? 96.750  96.052  98.302  1.00 73.96  ? 299 LEU A CD2 1 
ATOM   1991 N N   . SER A 1 319 ? 93.876  95.356  102.623 1.00 74.70  ? 300 SER A N   1 
ATOM   1992 C CA  . SER A 1 319 ? 93.022  96.002  103.608 1.00 74.70  ? 300 SER A CA  1 
ATOM   1993 C C   . SER A 1 319 ? 93.744  96.160  104.932 1.00 74.70  ? 300 SER A C   1 
ATOM   1994 O O   . SER A 1 319 ? 93.437  97.065  105.706 1.00 74.70  ? 300 SER A O   1 
ATOM   1995 C CB  . SER A 1 319 ? 91.742  95.193  103.807 1.00 74.70  ? 300 SER A CB  1 
ATOM   1996 O OG  . SER A 1 319 ? 91.956  94.116  104.703 1.00 74.70  ? 300 SER A OG  1 
ATOM   1997 N N   . SER A 1 320 ? 94.708  95.288  105.196 1.00 73.78  ? 301 SER A N   1 
ATOM   1998 C CA  . SER A 1 320 ? 95.408  95.326  106.473 1.00 73.78  ? 301 SER A CA  1 
ATOM   1999 C C   . SER A 1 320 ? 96.257  96.575  106.632 1.00 73.78  ? 301 SER A C   1 
ATOM   2000 O O   . SER A 1 320 ? 97.280  96.720  105.968 1.00 73.78  ? 301 SER A O   1 
ATOM   2001 C CB  . SER A 1 320 ? 96.285  94.084  106.629 1.00 73.78  ? 301 SER A CB  1 
ATOM   2002 O OG  . SER A 1 320 ? 95.575  92.904  106.298 1.00 73.78  ? 301 SER A OG  1 
ATOM   2003 N N   . ASP A 1 321 ? 95.843  97.479  107.513 1.00 76.65  ? 302 ASP A N   1 
ATOM   2004 C CA  . ASP A 1 321 ? 96.647  98.667  107.783 1.00 76.65  ? 302 ASP A CA  1 
ATOM   2005 C C   . ASP A 1 321 ? 97.918  98.231  108.473 1.00 76.65  ? 302 ASP A C   1 
ATOM   2006 O O   . ASP A 1 321 ? 98.882  98.990  108.544 1.00 76.65  ? 302 ASP A O   1 
ATOM   2007 C CB  . ASP A 1 321 ? 95.873  99.651  108.650 1.00 76.65  ? 302 ASP A CB  1 
ATOM   2008 C CG  . ASP A 1 321 ? 94.374  99.471  108.531 1.00 76.65  ? 302 ASP A CG  1 
ATOM   2009 O OD1 . ASP A 1 321 ? 93.864  99.476  107.391 1.00 76.65  ? 302 ASP A OD1 1 
ATOM   2010 O OD2 . ASP A 1 321 ? 93.707  99.319  109.576 1.00 76.65  ? 302 ASP A OD2 1 
ATOM   2011 N N   . ALA A 1 322 ? 97.918  97.017  109.009 1.00 71.11  ? 303 ALA A N   1 
ATOM   2012 C CA  . ALA A 1 322 ? 99.109  96.470  109.629 1.00 71.11  ? 303 ALA A CA  1 
ATOM   2013 C C   . ALA A 1 322 ? 99.181  95.072  109.077 1.00 71.11  ? 303 ALA A C   1 
ATOM   2014 O O   . ALA A 1 322 ? 98.867  94.105  109.769 1.00 71.11  ? 303 ALA A O   1 
ATOM   2015 C CB  . ALA A 1 322 ? 98.984  96.476  111.131 1.00 71.11  ? 303 ALA A CB  1 
ATOM   2016 N N   . VAL A 1 323 ? 99.576  94.954  107.818 1.00 65.63  ? 304 VAL A N   1 
ATOM   2017 C CA  . VAL A 1 323 ? 99.582  93.656  107.152 1.00 65.63  ? 304 VAL A CA  1 
ATOM   2018 C C   . VAL A 1 323 ? 100.316 92.616  107.987 1.00 65.63  ? 304 VAL A C   1 
ATOM   2019 O O   . VAL A 1 323 ? 99.867  91.470  108.104 1.00 65.63  ? 304 VAL A O   1 
ATOM   2020 C CB  . VAL A 1 323 ? 100.186 93.785  105.745 1.00 65.63  ? 304 VAL A CB  1 
ATOM   2021 C CG1 . VAL A 1 323 ? 100.206 92.440  105.061 1.00 65.63  ? 304 VAL A CG1 1 
ATOM   2022 C CG2 . VAL A 1 323 ? 99.388  94.777  104.931 1.00 65.63  ? 304 VAL A CG2 1 
ATOM   2023 N N   . ALA A 1 324 ? 101.450 92.989  108.581 1.00 63.48  ? 305 ALA A N   1 
ATOM   2024 C CA  . ALA A 1 324 ? 102.180 92.027  109.398 1.00 63.48  ? 305 ALA A CA  1 
ATOM   2025 C C   . ALA A 1 324 ? 101.416 91.680  110.666 1.00 63.48  ? 305 ALA A C   1 
ATOM   2026 O O   . ALA A 1 324 ? 101.505 90.548  111.148 1.00 63.48  ? 305 ALA A O   1 
ATOM   2027 C CB  . ALA A 1 324 ? 103.567 92.562  109.743 1.00 63.48  ? 305 ALA A CB  1 
ATOM   2028 N N   . VAL A 1 325 ? 100.645 92.625  111.207 1.00 64.33  ? 306 VAL A N   1 
ATOM   2029 C CA  . VAL A 1 325 ? 99.826  92.327  112.378 1.00 64.33  ? 306 VAL A CA  1 
ATOM   2030 C C   . VAL A 1 325 ? 98.716  91.347  112.017 1.00 64.33  ? 306 VAL A C   1 
ATOM   2031 O O   . VAL A 1 325 ? 98.414  90.418  112.778 1.00 64.33  ? 306 VAL A O   1 
ATOM   2032 C CB  . VAL A 1 325 ? 99.266  93.628  112.975 1.00 64.33  ? 306 VAL A CB  1 
ATOM   2033 C CG1 . VAL A 1 325 ? 98.279  93.319  114.080 1.00 64.33  ? 306 VAL A CG1 1 
ATOM   2034 C CG2 . VAL A 1 325 ? 100.398 94.496  113.493 1.00 64.33  ? 306 VAL A CG2 1 
ATOM   2035 N N   . THR A 1 326 ? 98.085  91.543  110.857 1.00 69.45  ? 307 THR A N   1 
ATOM   2036 C CA  . THR A 1 326 ? 97.102  90.580  110.371 1.00 69.45  ? 307 THR A CA  1 
ATOM   2037 C C   . THR A 1 326 ? 97.731  89.206  110.180 1.00 69.45  ? 307 THR A C   1 
ATOM   2038 O O   . THR A 1 326 ? 97.137  88.187  110.550 1.00 69.45  ? 307 THR A O   1 
ATOM   2039 C CB  . THR A 1 326 ? 96.486  91.075  109.063 1.00 69.45  ? 307 THR A CB  1 
ATOM   2040 O OG1 . THR A 1 326 ? 95.699  92.244  109.317 1.00 69.45  ? 307 THR A OG1 1 
ATOM   2041 C CG2 . THR A 1 326 ? 95.600  90.011  108.456 1.00 69.45  ? 307 THR A CG2 1 
ATOM   2042 N N   . PHE A 1 327 ? 98.932  89.159  109.600 1.00 64.54  ? 308 PHE A N   1 
ATOM   2043 C CA  . PHE A 1 327 ? 99.642  87.892  109.460 1.00 64.54  ? 308 PHE A CA  1 
ATOM   2044 C C   . PHE A 1 327 ? 99.879  87.240  110.815 1.00 64.54  ? 308 PHE A C   1 
ATOM   2045 O O   . PHE A 1 327 ? 99.712  86.025  110.964 1.00 64.54  ? 308 PHE A O   1 
ATOM   2046 C CB  . PHE A 1 327 ? 100.968 88.114  108.735 1.00 64.54  ? 308 PHE A CB  1 
ATOM   2047 C CG  . PHE A 1 327 ? 101.727 86.851  108.453 1.00 64.54  ? 308 PHE A CG  1 
ATOM   2048 C CD1 . PHE A 1 327 ? 102.572 86.308  109.398 1.00 64.54  ? 308 PHE A CD1 1 
ATOM   2049 C CD2 . PHE A 1 327 ? 101.613 86.222  107.233 1.00 64.54  ? 308 PHE A CD2 1 
ATOM   2050 C CE1 . PHE A 1 327 ? 103.273 85.156  109.136 1.00 64.54  ? 308 PHE A CE1 1 
ATOM   2051 C CE2 . PHE A 1 327 ? 102.315 85.070  106.968 1.00 64.54  ? 308 PHE A CE2 1 
ATOM   2052 C CZ  . PHE A 1 327 ? 103.143 84.537  107.921 1.00 64.54  ? 308 PHE A CZ  1 
ATOM   2053 N N   . ALA A 1 328 ? 100.293 88.030  111.807 1.00 70.56  ? 309 ALA A N   1 
ATOM   2054 C CA  . ALA A 1 328 ? 100.501 87.498  113.149 1.00 70.56  ? 309 ALA A CA  1 
ATOM   2055 C C   . ALA A 1 328 ? 99.218  86.896  113.701 1.00 70.56  ? 309 ALA A C   1 
ATOM   2056 O O   . ALA A 1 328 ? 99.220  85.786  114.245 1.00 70.56  ? 309 ALA A O   1 
ATOM   2057 C CB  . ALA A 1 328 ? 101.015 88.596  114.077 1.00 70.56  ? 309 ALA A CB  1 
ATOM   2058 N N   . ASP A 1 329 ? 98.107  87.620  113.568 1.00 76.18  ? 310 ASP A N   1 
ATOM   2059 C CA  . ASP A 1 329 ? 96.833  87.106  114.058 1.00 76.18  ? 310 ASP A CA  1 
ATOM   2060 C C   . ASP A 1 329 ? 96.420  85.835  113.328 1.00 76.18  ? 310 ASP A C   1 
ATOM   2061 O O   . ASP A 1 329 ? 95.810  84.944  113.929 1.00 76.18  ? 310 ASP A O   1 
ATOM   2062 C CB  . ASP A 1 329 ? 95.750  88.174  113.919 1.00 76.18  ? 310 ASP A CB  1 
ATOM   2063 C CG  . ASP A 1 329 ? 95.523  88.939  115.204 1.00 76.18  ? 310 ASP A CG  1 
ATOM   2064 O OD1 . ASP A 1 329 ? 96.007  88.481  116.260 1.00 76.18  ? 310 ASP A OD1 1 
ATOM   2065 O OD2 . ASP A 1 329 ? 94.862  89.997  115.159 1.00 76.18  ? 310 ASP A OD2 1 
ATOM   2066 N N   . GLN A 1 330 ? 96.746  85.729  112.040 1.00 74.10  ? 311 GLN A N   1 
ATOM   2067 C CA  . GLN A 1 330 ? 96.309  84.577  111.260 1.00 74.10  ? 311 GLN A CA  1 
ATOM   2068 C C   . GLN A 1 330 ? 97.149  83.337  111.543 1.00 74.10  ? 311 GLN A C   1 
ATOM   2069 O O   . GLN A 1 330 ? 96.597  82.254  111.761 1.00 74.10  ? 311 GLN A O   1 
ATOM   2070 C CB  . GLN A 1 330 ? 96.345  84.911  109.770 1.00 74.10  ? 311 GLN A CB  1 
ATOM   2071 C CG  . GLN A 1 330 ? 95.320  85.946  109.345 1.00 74.10  ? 311 GLN A CG  1 
ATOM   2072 C CD  . GLN A 1 330 ? 93.930  85.370  109.201 1.00 74.10  ? 311 GLN A CD  1 
ATOM   2073 O OE1 . GLN A 1 330 ? 93.756  84.263  108.695 1.00 74.10  ? 311 GLN A OE1 1 
ATOM   2074 N NE2 . GLN A 1 330 ? 92.928  86.123  109.641 1.00 74.10  ? 311 GLN A NE2 1 
ATOM   2075 N N   . THR A 1 331 ? 98.473  83.467  111.550 1.00 76.84  ? 312 THR A N   1 
ATOM   2076 C CA  . THR A 1 331 ? 99.363  82.315  111.659 1.00 76.84  ? 312 THR A CA  1 
ATOM   2077 C C   . THR A 1 331 ? 99.932  82.113  113.053 1.00 76.84  ? 312 THR A C   1 
ATOM   2078 O O   . THR A 1 331 ? 99.908  80.991  113.563 1.00 76.84  ? 312 THR A O   1 
ATOM   2079 C CB  . THR A 1 331 ? 100.516 82.438  110.657 1.00 76.84  ? 312 THR A CB  1 
ATOM   2080 O OG1 . THR A 1 331 ? 100.030 82.160  109.339 1.00 76.84  ? 312 THR A OG1 1 
ATOM   2081 C CG2 . THR A 1 331 ? 101.625 81.459  110.986 1.00 76.84  ? 312 THR A CG2 1 
ATOM   2082 N N   . PHE A 1 332 ? 100.433 83.161  113.697 1.00 79.30  ? 313 PHE A N   1 
ATOM   2083 C CA  . PHE A 1 332 ? 100.891 83.040  115.078 1.00 79.30  ? 313 PHE A CA  1 
ATOM   2084 C C   . PHE A 1 332 ? 99.653  82.912  115.954 1.00 79.30  ? 313 PHE A C   1 
ATOM   2085 O O   . PHE A 1 332 ? 99.052  83.905  116.368 1.00 79.30  ? 313 PHE A O   1 
ATOM   2086 C CB  . PHE A 1 332 ? 101.738 84.240  115.487 1.00 79.30  ? 313 PHE A CB  1 
ATOM   2087 C CG  . PHE A 1 332 ? 103.009 84.388  114.706 1.00 79.30  ? 313 PHE A CG  1 
ATOM   2088 C CD1 . PHE A 1 332 ? 103.937 83.366  114.667 1.00 79.30  ? 313 PHE A CD1 1 
ATOM   2089 C CD2 . PHE A 1 332 ? 103.280 85.558  114.023 1.00 79.30  ? 313 PHE A CD2 1 
ATOM   2090 C CE1 . PHE A 1 332 ? 105.107 83.506  113.952 1.00 79.30  ? 313 PHE A CE1 1 
ATOM   2091 C CE2 . PHE A 1 332 ? 104.446 85.702  113.308 1.00 79.30  ? 313 PHE A CE2 1 
ATOM   2092 C CZ  . PHE A 1 332 ? 105.361 84.675  113.272 1.00 79.30  ? 313 PHE A CZ  1 
ATOM   2093 N N   . GLY A 1 333 ? 99.256  81.671  116.227 1.00 80.51  ? 314 GLY A N   1 
ATOM   2094 C CA  . GLY A 1 333 ? 98.109  81.427  117.080 1.00 80.51  ? 314 GLY A CA  1 
ATOM   2095 C C   . GLY A 1 333 ? 98.308  82.075  118.430 1.00 80.51  ? 314 GLY A C   1 
ATOM   2096 O O   . GLY A 1 333 ? 97.619  83.040  118.775 1.00 80.51  ? 314 GLY A O   1 
ATOM   2097 N N   . MET A 1 334 ? 99.258  81.557  119.199 1.00 82.91  ? 315 MET A N   1 
ATOM   2098 C CA  . MET A 1 334 ? 99.780  82.287  120.337 1.00 82.91  ? 315 MET A CA  1 
ATOM   2099 C C   . MET A 1 334 ? 100.901 83.201  119.849 1.00 82.91  ? 315 MET A C   1 
ATOM   2100 O O   . MET A 1 334 ? 101.260 83.205  118.670 1.00 82.91  ? 315 MET A O   1 
ATOM   2101 C CB  . MET A 1 334 ? 100.257 81.326  121.425 1.00 82.91  ? 315 MET A CB  1 
ATOM   2102 C CG  . MET A 1 334 ? 100.128 81.873  122.840 1.00 82.91  ? 315 MET A CG  1 
ATOM   2103 S SD  . MET A 1 334 ? 98.438  82.342  123.263 1.00 82.91  ? 315 MET A SD  1 
ATOM   2104 C CE  . MET A 1 334 ? 98.520  84.127  123.113 1.00 82.91  ? 315 MET A CE  1 
ATOM   2105 N N   . PHE A 1 335 ? 101.460 83.989  120.766 1.00 80.21  ? 316 PHE A N   1 
ATOM   2106 C CA  . PHE A 1 335 ? 102.551 84.909  120.446 1.00 80.21  ? 316 PHE A CA  1 
ATOM   2107 C C   . PHE A 1 335 ? 102.170 85.858  119.315 1.00 80.21  ? 316 PHE A C   1 
ATOM   2108 O O   . PHE A 1 335 ? 103.000 86.206  118.473 1.00 80.21  ? 316 PHE A O   1 
ATOM   2109 C CB  . PHE A 1 335 ? 103.833 84.150  120.096 1.00 80.21  ? 316 PHE A CB  1 
ATOM   2110 C CG  . PHE A 1 335 ? 104.119 82.994  121.005 1.00 80.21  ? 316 PHE A CG  1 
ATOM   2111 C CD1 . PHE A 1 335 ? 104.786 83.188  122.200 1.00 80.21  ? 316 PHE A CD1 1 
ATOM   2112 C CD2 . PHE A 1 335 ? 103.727 81.713  120.662 1.00 80.21  ? 316 PHE A CD2 1 
ATOM   2113 C CE1 . PHE A 1 335 ? 105.051 82.127  123.039 1.00 80.21  ? 316 PHE A CE1 1 
ATOM   2114 C CE2 . PHE A 1 335 ? 103.988 80.649  121.497 1.00 80.21  ? 316 PHE A CE2 1 
ATOM   2115 C CZ  . PHE A 1 335 ? 104.652 80.856  122.687 1.00 80.21  ? 316 PHE A CZ  1 
ATOM   2116 N N   . SER A 1 336 ? 100.907 86.279  119.281 1.00 76.17  ? 317 SER A N   1 
ATOM   2117 C CA  . SER A 1 336 ? 100.494 87.289  118.319 1.00 76.17  ? 317 SER A CA  1 
ATOM   2118 C C   . SER A 1 336 ? 101.043 88.664  118.660 1.00 76.17  ? 317 SER A C   1 
ATOM   2119 O O   . SER A 1 336 ? 101.009 89.558  117.811 1.00 76.17  ? 317 SER A O   1 
ATOM   2120 C CB  . SER A 1 336 ? 98.969  87.355  118.234 1.00 76.17  ? 317 SER A CB  1 
ATOM   2121 O OG  . SER A 1 336 ? 98.552  88.599  117.699 1.00 76.17  ? 317 SER A OG  1 
ATOM   2122 N N   . TRP A 1 337 ? 101.544 88.846  119.880 1.00 70.51  ? 318 TRP A N   1 
ATOM   2123 C CA  . TRP A 1 337 ? 102.199 90.073  120.299 1.00 70.51  ? 318 TRP A CA  1 
ATOM   2124 C C   . TRP A 1 337 ? 103.689 90.064  119.998 1.00 70.51  ? 318 TRP A C   1 
ATOM   2125 O O   . TRP A 1 337 ? 104.432 90.866  120.572 1.00 70.51  ? 318 TRP A O   1 
ATOM   2126 C CB  . TRP A 1 337 ? 101.972 90.303  121.793 1.00 70.51  ? 318 TRP A CB  1 
ATOM   2127 C CG  . TRP A 1 337 ? 102.156 89.064  122.598 1.00 70.51  ? 318 TRP A CG  1 
ATOM   2128 C CD1 . TRP A 1 337 ? 101.191 88.169  122.955 1.00 70.51  ? 318 TRP A CD1 1 
ATOM   2129 C CD2 . TRP A 1 337 ? 103.385 88.564  123.138 1.00 70.51  ? 318 TRP A CD2 1 
ATOM   2130 N NE1 . TRP A 1 337 ? 101.740 87.149  123.691 1.00 70.51  ? 318 TRP A NE1 1 
ATOM   2131 C CE2 . TRP A 1 337 ? 103.087 87.367  123.817 1.00 70.51  ? 318 TRP A CE2 1 
ATOM   2132 C CE3 . TRP A 1 337 ? 104.707 89.016  123.116 1.00 70.51  ? 318 TRP A CE3 1 
ATOM   2133 C CZ2 . TRP A 1 337 ? 104.062 86.615  124.468 1.00 70.51  ? 318 TRP A CZ2 1 
ATOM   2134 C CZ3 . TRP A 1 337 ? 105.676 88.268  123.764 1.00 70.51  ? 318 TRP A CZ3 1 
ATOM   2135 C CH2 . TRP A 1 337 ? 105.347 87.081  124.430 1.00 70.51  ? 318 TRP A CH2 1 
ATOM   2136 N N   . THR A 1 338 ? 104.145 89.172  119.124 1.00 64.31  ? 319 THR A N   1 
ATOM   2137 C CA  . THR A 1 338 ? 105.544 89.174  118.721 1.00 64.31  ? 319 THR A CA  1 
ATOM   2138 C C   . THR A 1 338 ? 105.786 90.133  117.567 1.00 64.31  ? 319 THR A C   1 
ATOM   2139 O O   . THR A 1 338 ? 106.796 90.841  117.554 1.00 64.31  ? 319 THR A O   1 
ATOM   2140 C CB  . THR A 1 338 ? 105.992 87.758  118.342 1.00 64.31  ? 319 THR A CB  1 
ATOM   2141 O OG1 . THR A 1 338 ? 106.167 86.979  119.530 1.00 64.31  ? 319 THR A OG1 1 
ATOM   2142 C CG2 . THR A 1 338 ? 107.304 87.787  117.574 1.00 64.31  ? 319 THR A CG2 1 
ATOM   2143 N N   . ILE A 1 339 ? 104.853 90.219  116.626 1.00 53.99  ? 320 ILE A N   1 
ATOM   2144 C CA  . ILE A 1 339 ? 105.011 91.090  115.463 1.00 53.99  ? 320 ILE A CA  1 
ATOM   2145 C C   . ILE A 1 339 ? 104.823 92.561  115.831 1.00 53.99  ? 320 ILE A C   1 
ATOM   2146 O O   . ILE A 1 339 ? 105.531 93.409  115.276 1.00 53.99  ? 320 ILE A O   1 
ATOM   2147 C CB  . ILE A 1 339 ? 104.066 90.667  114.329 1.00 53.99  ? 320 ILE A CB  1 
ATOM   2148 C CG1 . ILE A 1 339 ? 104.487 89.302  113.792 1.00 53.99  ? 320 ILE A CG1 1 
ATOM   2149 C CG2 . ILE A 1 339 ? 104.088 91.678  113.210 1.00 53.99  ? 320 ILE A CG2 1 
ATOM   2150 C CD1 . ILE A 1 339 ? 105.853 89.299  113.167 1.00 53.99  ? 320 ILE A CD1 1 
ATOM   2151 N N   . PRO A 1 340 ? 103.901 92.938  116.736 1.00 53.02  ? 321 PRO A N   1 
ATOM   2152 C CA  . PRO A 1 340 ? 103.894 94.334  117.201 1.00 53.02  ? 321 PRO A CA  1 
ATOM   2153 C C   . PRO A 1 340 ? 105.183 94.738  117.904 1.00 53.02  ? 321 PRO A C   1 
ATOM   2154 O O   . PRO A 1 340 ? 105.692 95.840  117.677 1.00 53.02  ? 321 PRO A O   1 
ATOM   2155 C CB  . PRO A 1 340 ? 102.696 94.376  118.152 1.00 53.02  ? 321 PRO A CB  1 
ATOM   2156 C CG  . PRO A 1 340 ? 101.783 93.360  117.609 1.00 53.02  ? 321 PRO A CG  1 
ATOM   2157 C CD  . PRO A 1 340 ? 102.661 92.244  117.127 1.00 53.02  ? 321 PRO A CD  1 
ATOM   2158 N N   . ILE A 1 341 ? 105.728 93.862  118.746 1.00 49.09  ? 322 ILE A N   1 
ATOM   2159 C CA  . ILE A 1 341 ? 107.039 94.093  119.345 1.00 49.09  ? 322 ILE A CA  1 
ATOM   2160 C C   . ILE A 1 341 ? 108.076 94.248  118.244 1.00 49.09  ? 322 ILE A C   1 
ATOM   2161 O O   . ILE A 1 341 ? 108.976 95.088  118.339 1.00 49.09  ? 322 ILE A O   1 
ATOM   2162 C CB  . ILE A 1 341 ? 107.440 92.962  120.310 1.00 49.09  ? 322 ILE A CB  1 
ATOM   2163 C CG1 . ILE A 1 341 ? 106.564 92.973  121.556 1.00 49.09  ? 322 ILE A CG1 1 
ATOM   2164 C CG2 . ILE A 1 341 ? 108.893 93.084  120.713 1.00 49.09  ? 322 ILE A CG2 1 
ATOM   2165 C CD1 . ILE A 1 341 ? 106.805 91.781  122.455 1.00 49.09  ? 322 ILE A CD1 1 
ATOM   2166 N N   . ALA A 1 342 ? 107.967 93.432  117.197 1.00 46.23  ? 323 ALA A N   1 
ATOM   2167 C CA  . ALA A 1 342 ? 108.953 93.471  116.126 1.00 46.23  ? 323 ALA A CA  1 
ATOM   2168 C C   . ALA A 1 342 ? 108.896 94.789  115.373 1.00 46.23  ? 323 ALA A C   1 
ATOM   2169 O O   . ALA A 1 342 ? 109.930 95.366  115.030 1.00 46.23  ? 323 ALA A O   1 
ATOM   2170 C CB  . ALA A 1 342 ? 108.729 92.304  115.173 1.00 46.23  ? 323 ALA A CB  1 
ATOM   2171 N N   . VAL A 1 343 ? 107.689 95.298  115.129 1.00 42.92  ? 324 VAL A N   1 
ATOM   2172 C CA  . VAL A 1 343 ? 107.553 96.572  114.425 1.00 42.92  ? 324 VAL A CA  1 
ATOM   2173 C C   . VAL A 1 343 ? 108.013 97.716  115.317 1.00 42.92  ? 324 VAL A C   1 
ATOM   2174 O O   . VAL A 1 343 ? 108.572 98.711  114.844 1.00 42.92  ? 324 VAL A O   1 
ATOM   2175 C CB  . VAL A 1 343 ? 106.107 96.778  113.944 1.00 42.92  ? 324 VAL A CB  1 
ATOM   2176 C CG1 . VAL A 1 343 ? 105.996 98.062  113.156 1.00 42.92  ? 324 VAL A CG1 1 
ATOM   2177 C CG2 . VAL A 1 343 ? 105.671 95.613  113.093 1.00 42.92  ? 324 VAL A CG2 1 
ATOM   2178 N N   . ALA A 1 344 ? 107.810 97.582  116.627 1.00 39.23  ? 325 ALA A N   1 
ATOM   2179 C CA  . ALA A 1 344 ? 108.306 98.595  117.551 1.00 39.23  ? 325 ALA A CA  1 
ATOM   2180 C C   . ALA A 1 344 ? 109.830 98.639  117.547 1.00 39.23  ? 325 ALA A C   1 
ATOM   2181 O O   . ALA A 1 344 ? 110.438 99.709  117.432 1.00 39.23  ? 325 ALA A O   1 
ATOM   2182 C CB  . ALA A 1 344 ? 107.779 98.323  118.956 1.00 39.23  ? 325 ALA A CB  1 
ATOM   2183 N N   . LEU A 1 345 ? 110.465 97.475  117.685 1.00 36.30  ? 326 LEU A N   1 
ATOM   2184 C CA  . LEU A 1 345 ? 111.921 97.415  117.639 1.00 36.30  ? 326 LEU A CA  1 
ATOM   2185 C C   . LEU A 1 345 ? 112.440 97.886  116.288 1.00 36.30  ? 326 LEU A C   1 
ATOM   2186 O O   . LEU A 1 345 ? 113.511 98.493  116.197 1.00 36.30  ? 326 LEU A O   1 
ATOM   2187 C CB  . LEU A 1 345 ? 112.405 95.997  117.934 1.00 36.30  ? 326 LEU A CB  1 
ATOM   2188 C CG  . LEU A 1 345 ? 112.066 95.441  119.314 1.00 36.30  ? 326 LEU A CG  1 
ATOM   2189 C CD1 . LEU A 1 345 ? 112.594 94.029  119.453 1.00 36.30  ? 326 LEU A CD1 1 
ATOM   2190 C CD2 . LEU A 1 345 ? 112.596 96.330  120.413 1.00 36.30  ? 326 LEU A CD2 1 
ATOM   2191 N N   . SER A 1 346 ? 111.680 97.628  115.224 1.00 38.45  ? 327 SER A N   1 
ATOM   2192 C CA  . SER A 1 346 ? 112.085 98.084  113.901 1.00 38.45  ? 327 SER A CA  1 
ATOM   2193 C C   . SER A 1 346 ? 112.054 99.599  113.808 1.00 38.45  ? 327 SER A C   1 
ATOM   2194 O O   . SER A 1 346 ? 112.992 100.216 113.301 1.00 38.45  ? 327 SER A O   1 
ATOM   2195 C CB  . SER A 1 346 ? 111.181 97.471  112.837 1.00 38.45  ? 327 SER A CB  1 
ATOM   2196 O OG  . SER A 1 346 ? 111.730 97.659  111.548 1.00 38.45  ? 327 SER A OG  1 
ATOM   2197 N N   . CYS A 1 347 ? 110.977 100.222 114.286 1.00 33.79  ? 328 CYS A N   1 
ATOM   2198 C CA  . CYS A 1 347 ? 110.897 101.676 114.216 1.00 33.79  ? 328 CYS A CA  1 
ATOM   2199 C C   . CYS A 1 347 ? 111.925 102.325 115.130 1.00 33.79  ? 328 CYS A C   1 
ATOM   2200 O O   . CYS A 1 347 ? 112.425 103.415 114.838 1.00 33.79  ? 328 CYS A O   1 
ATOM   2201 C CB  . CYS A 1 347 ? 109.491 102.144 114.563 1.00 33.79  ? 328 CYS A CB  1 
ATOM   2202 S SG  . CYS A 1 347 ? 108.301 101.809 113.260 1.00 33.79  ? 328 CYS A SG  1 
ATOM   2203 N N   . PHE A 1 348 ? 112.289 101.654 116.222 1.00 30.79  ? 329 PHE A N   1 
ATOM   2204 C CA  . PHE A 1 348 ? 113.368 102.184 117.047 1.00 30.79  ? 329 PHE A CA  1 
ATOM   2205 C C   . PHE A 1 348 ? 114.702 102.103 116.316 1.00 30.79  ? 329 PHE A C   1 
ATOM   2206 O O   . PHE A 1 348 ? 115.347 103.128 116.078 1.00 30.79  ? 329 PHE A O   1 
ATOM   2207 C CB  . PHE A 1 348 ? 113.444 101.438 118.374 1.00 30.79  ? 329 PHE A CB  1 
ATOM   2208 C CG  . PHE A 1 348 ? 114.247 102.148 119.421 1.00 30.79  ? 329 PHE A CG  1 
ATOM   2209 C CD1 . PHE A 1 348 ? 113.781 103.304 119.996 1.00 30.79  ? 329 PHE A CD1 1 
ATOM   2210 C CD2 . PHE A 1 348 ? 115.474 101.667 119.817 1.00 30.79  ? 329 PHE A CD2 1 
ATOM   2211 C CE1 . PHE A 1 348 ? 114.514 103.954 120.958 1.00 30.79  ? 329 PHE A CE1 1 
ATOM   2212 C CE2 . PHE A 1 348 ? 116.209 102.315 120.779 1.00 30.79  ? 329 PHE A CE2 1 
ATOM   2213 C CZ  . PHE A 1 348 ? 115.729 103.457 121.348 1.00 30.79  ? 329 PHE A CZ  1 
ATOM   2214 N N   . GLY A 1 349 ? 115.126 100.900 115.934 1.00 32.12  ? 330 GLY A N   1 
ATOM   2215 C CA  . GLY A 1 349 ? 116.369 100.748 115.201 1.00 32.12  ? 330 GLY A CA  1 
ATOM   2216 C C   . GLY A 1 349 ? 116.390 101.379 113.828 1.00 32.12  ? 330 GLY A C   1 
ATOM   2217 O O   . GLY A 1 349 ? 117.429 101.348 113.165 1.00 32.12  ? 330 GLY A O   1 
ATOM   2218 N N   . GLY A 1 350 ? 115.271 101.934 113.378 1.00 30.18  ? 331 GLY A N   1 
ATOM   2219 C CA  . GLY A 1 350 ? 115.240 102.672 112.135 1.00 30.18  ? 331 GLY A CA  1 
ATOM   2220 C C   . GLY A 1 350 ? 115.007 104.142 112.394 1.00 30.18  ? 331 GLY A C   1 
ATOM   2221 O O   . GLY A 1 350 ? 114.912 104.946 111.463 1.00 30.18  ? 331 GLY A O   1 
ATOM   2222 N N   . LEU A 1 351 ? 114.883 104.497 113.673 1.00 31.00  ? 332 LEU A N   1 
ATOM   2223 C CA  . LEU A 1 351 ? 115.017 105.894 114.064 1.00 31.00  ? 332 LEU A CA  1 
ATOM   2224 C C   . LEU A 1 351 ? 116.468 106.233 114.357 1.00 31.00  ? 332 LEU A C   1 
ATOM   2225 O O   . LEU A 1 351 ? 116.953 107.305 113.982 1.00 31.00  ? 332 LEU A O   1 
ATOM   2226 C CB  . LEU A 1 351 ? 114.149 106.190 115.280 1.00 31.00  ? 332 LEU A CB  1 
ATOM   2227 C CG  . LEU A 1 351 ? 114.277 107.616 115.790 1.00 31.00  ? 332 LEU A CG  1 
ATOM   2228 C CD1 . LEU A 1 351 ? 113.872 108.572 114.711 1.00 31.00  ? 332 LEU A CD1 1 
ATOM   2229 C CD2 . LEU A 1 351 ? 113.408 107.792 117.003 1.00 31.00  ? 332 LEU A CD2 1 
ATOM   2230 N N   . ASN A 1 352 ? 117.184 105.323 115.019 1.00 32.28  ? 333 ASN A N   1 
ATOM   2231 C CA  . ASN A 1 352 ? 118.594 105.557 115.302 1.00 32.28  ? 333 ASN A CA  1 
ATOM   2232 C C   . ASN A 1 352 ? 119.428 105.512 114.025 1.00 32.28  ? 333 ASN A C   1 
ATOM   2233 O O   . ASN A 1 352 ? 120.647 105.701 114.063 1.00 32.28  ? 333 ASN A O   1 
ATOM   2234 C CB  . ASN A 1 352 ? 119.092 104.536 116.320 1.00 32.28  ? 333 ASN A CB  1 
ATOM   2235 C CG  . ASN A 1 352 ? 120.525 104.757 116.704 1.00 32.28  ? 333 ASN A CG  1 
ATOM   2236 O OD1 . ASN A 1 352 ? 120.830 105.603 117.537 1.00 32.28  ? 333 ASN A OD1 1 
ATOM   2237 N ND2 . ASN A 1 352 ? 121.423 104.010 116.085 1.00 32.28  ? 333 ASN A ND2 1 
ATOM   2238 N N   . ALA A 1 353 ? 118.791 105.261 112.882 1.00 31.95  ? 334 ALA A N   1 
ATOM   2239 C CA  . ALA A 1 353 ? 119.497 105.368 111.612 1.00 31.95  ? 334 ALA A CA  1 
ATOM   2240 C C   . ALA A 1 353 ? 119.146 106.668 110.908 1.00 31.95  ? 334 ALA A C   1 
ATOM   2241 O O   . ALA A 1 353 ? 119.764 107.029 109.902 1.00 31.95  ? 334 ALA A O   1 
ATOM   2242 C CB  . ALA A 1 353 ? 119.174 104.172 110.723 1.00 31.95  ? 334 ALA A CB  1 
ATOM   2243 N N   . SER A 1 354 ? 118.147 107.378 111.410 1.00 31.02  ? 335 SER A N   1 
ATOM   2244 C CA  . SER A 1 354 ? 117.859 108.716 110.909 1.00 31.02  ? 335 SER A CA  1 
ATOM   2245 C C   . SER A 1 354 ? 118.254 109.782 111.883 1.00 31.02  ? 335 SER A C   1 
ATOM   2246 O O   . SER A 1 354 ? 117.929 110.952 111.688 1.00 31.02  ? 335 SER A O   1 
ATOM   2247 C CB  . SER A 1 354 ? 116.378 108.850 110.567 1.00 31.02  ? 335 SER A CB  1 
ATOM   2248 O OG  . SER A 1 354 ? 115.919 107.719 109.854 1.00 31.02  ? 335 SER A OG  1 
ATOM   2249 N N   . ILE A 1 355 ? 118.935 109.368 112.949 1.00 29.25  ? 336 ILE A N   1 
ATOM   2250 C CA  . ILE A 1 355 ? 119.588 110.289 113.860 1.00 29.25  ? 336 ILE A CA  1 
ATOM   2251 C C   . ILE A 1 355 ? 121.104 110.120 113.842 1.00 29.25  ? 336 ILE A C   1 
ATOM   2252 O O   . ILE A 1 355 ? 121.829 111.083 114.114 1.00 29.25  ? 336 ILE A O   1 
ATOM   2253 C CB  . ILE A 1 355 ? 119.031 110.118 115.287 1.00 29.25  ? 336 ILE A CB  1 
ATOM   2254 C CG1 . ILE A 1 355 ? 117.561 110.509 115.325 1.00 29.25  ? 336 ILE A CG1 1 
ATOM   2255 C CG2 . ILE A 1 355 ? 119.762 110.965 116.274 1.00 29.25  ? 336 ILE A CG2 1 
ATOM   2256 C CD1 . ILE A 1 355 ? 116.899 110.193 116.629 1.00 29.25  ? 336 ILE A CD1 1 
ATOM   2257 N N   . PHE A 1 356 ? 121.598 108.936 113.491 1.00 33.93  ? 337 PHE A N   1 
ATOM   2258 C CA  . PHE A 1 356 ? 123.015 108.703 113.269 1.00 33.93  ? 337 PHE A CA  1 
ATOM   2259 C C   . PHE A 1 356 ? 123.430 109.031 111.846 1.00 33.93  ? 337 PHE A C   1 
ATOM   2260 O O   . PHE A 1 356 ? 124.598 108.853 111.499 1.00 33.93  ? 337 PHE A O   1 
ATOM   2261 C CB  . PHE A 1 356 ? 123.332 107.244 113.586 1.00 33.93  ? 337 PHE A CB  1 
ATOM   2262 C CG  . PHE A 1 356 ? 124.788 106.938 113.701 1.00 33.93  ? 337 PHE A CG  1 
ATOM   2263 C CD1 . PHE A 1 356 ? 125.682 107.887 114.146 1.00 33.93  ? 337 PHE A CD1 1 
ATOM   2264 C CD2 . PHE A 1 356 ? 125.262 105.679 113.376 1.00 33.93  ? 337 PHE A CD2 1 
ATOM   2265 C CE1 . PHE A 1 356 ? 127.027 107.589 114.256 1.00 33.93  ? 337 PHE A CE1 1 
ATOM   2266 C CE2 . PHE A 1 356 ? 126.605 105.377 113.482 1.00 33.93  ? 337 PHE A CE2 1 
ATOM   2267 C CZ  . PHE A 1 356 ? 127.488 106.333 113.922 1.00 33.93  ? 337 PHE A CZ  1 
ATOM   2268 N N   . ALA A 1 357 ? 122.503 109.503 111.014 1.00 34.10  ? 338 ALA A N   1 
ATOM   2269 C CA  . ALA A 1 357 ? 122.789 109.839 109.625 1.00 34.10  ? 338 ALA A CA  1 
ATOM   2270 C C   . ALA A 1 357 ? 122.340 111.245 109.252 1.00 34.10  ? 338 ALA A C   1 
ATOM   2271 O O   . ALA A 1 357 ? 122.904 111.850 108.339 1.00 34.10  ? 338 ALA A O   1 
ATOM   2272 C CB  . ALA A 1 357 ? 122.127 108.825 108.690 1.00 34.10  ? 338 ALA A CB  1 
ATOM   2273 N N   . SER A 1 358 ? 121.324 111.777 109.932 1.00 34.72  ? 339 SER A N   1 
ATOM   2274 C CA  . SER A 1 358 ? 120.904 113.148 109.669 1.00 34.72  ? 339 SER A CA  1 
ATOM   2275 C C   . SER A 1 358 ? 121.770 114.140 110.428 1.00 34.72  ? 339 SER A C   1 
ATOM   2276 O O   . SER A 1 358 ? 122.230 115.139 109.862 1.00 34.72  ? 339 SER A O   1 
ATOM   2277 C CB  . SER A 1 358 ? 119.446 113.340 110.055 1.00 34.72  ? 339 SER A CB  1 
ATOM   2278 O OG  . SER A 1 358 ? 119.352 113.665 111.427 1.00 34.72  ? 339 SER A OG  1 
ATOM   2279 N N   . SER A 1 359 ? 121.992 113.889 111.716 1.00 34.97  ? 340 SER A N   1 
ATOM   2280 C CA  . SER A 1 359 ? 122.837 114.764 112.514 1.00 34.97  ? 340 SER A CA  1 
ATOM   2281 C C   . SER A 1 359 ? 124.282 114.789 112.040 1.00 34.97  ? 340 SER A C   1 
ATOM   2282 O O   . SER A 1 359 ? 125.080 115.543 112.600 1.00 34.97  ? 340 SER A O   1 
ATOM   2283 C CB  . SER A 1 359 ? 122.794 114.338 113.971 1.00 34.97  ? 340 SER A CB  1 
ATOM   2284 O OG  . SER A 1 359 ? 123.699 113.276 114.201 1.00 34.97  ? 340 SER A OG  1 
ATOM   2285 N N   . ARG A 1 360 ? 124.640 113.980 111.045 1.00 36.50  ? 341 ARG A N   1 
ATOM   2286 C CA  . ARG A 1 360 ? 125.896 114.167 110.337 1.00 36.50  ? 341 ARG A CA  1 
ATOM   2287 C C   . ARG A 1 360 ? 125.710 115.002 109.086 1.00 36.50  ? 341 ARG A C   1 
ATOM   2288 O O   . ARG A 1 360 ? 126.637 115.706 108.670 1.00 36.50  ? 341 ARG A O   1 
ATOM   2289 C CB  . ARG A 1 360 ? 126.514 112.822 109.965 1.00 36.50  ? 341 ARG A CB  1 
ATOM   2290 C CG  . ARG A 1 360 ? 127.540 112.343 110.955 1.00 36.50  ? 341 ARG A CG  1 
ATOM   2291 C CD  . ARG A 1 360 ? 126.906 112.068 112.300 1.00 36.50  ? 341 ARG A CD  1 
ATOM   2292 N NE  . ARG A 1 360 ? 127.750 111.240 113.152 1.00 36.50  ? 341 ARG A NE  1 
ATOM   2293 C CZ  . ARG A 1 360 ? 127.502 111.010 114.435 1.00 36.50  ? 341 ARG A CZ  1 
ATOM   2294 N NH1 . ARG A 1 360 ? 126.431 111.536 115.006 1.00 36.50  ? 341 ARG A NH1 1 
ATOM   2295 N NH2 . ARG A 1 360 ? 128.320 110.252 115.148 1.00 36.50  ? 341 ARG A NH2 1 
ATOM   2296 N N   . LEU A 1 361 ? 124.525 114.944 108.481 1.00 35.98  ? 342 LEU A N   1 
ATOM   2297 C CA  . LEU A 1 361 ? 124.201 115.867 107.404 1.00 35.98  ? 342 LEU A CA  1 
ATOM   2298 C C   . LEU A 1 361 ? 124.291 117.306 107.890 1.00 35.98  ? 342 LEU A C   1 
ATOM   2299 O O   . LEU A 1 361 ? 124.999 118.129 107.304 1.00 35.98  ? 342 LEU A O   1 
ATOM   2300 C CB  . LEU A 1 361 ? 122.811 115.569 106.851 1.00 35.98  ? 342 LEU A CB  1 
ATOM   2301 C CG  . LEU A 1 361 ? 122.486 116.416 105.637 1.00 35.98  ? 342 LEU A CG  1 
ATOM   2302 C CD1 . LEU A 1 361 ? 123.566 116.183 104.631 1.00 35.98  ? 342 LEU A CD1 1 
ATOM   2303 C CD2 . LEU A 1 361 ? 121.149 116.030 105.073 1.00 35.98  ? 342 LEU A CD2 1 
ATOM   2304 N N   . PHE A 1 362 ? 123.568 117.630 108.966 1.00 37.43  ? 343 PHE A N   1 
ATOM   2305 C CA  . PHE A 1 362 ? 123.673 118.969 109.543 1.00 37.43  ? 343 PHE A CA  1 
ATOM   2306 C C   . PHE A 1 362 ? 125.100 119.294 109.962 1.00 37.43  ? 343 PHE A C   1 
ATOM   2307 O O   . PHE A 1 362 ? 125.504 120.462 109.950 1.00 37.43  ? 343 PHE A O   1 
ATOM   2308 C CB  . PHE A 1 362 ? 122.739 119.113 110.741 1.00 37.43  ? 343 PHE A CB  1 
ATOM   2309 C CG  . PHE A 1 362 ? 121.306 118.843 110.425 1.00 37.43  ? 343 PHE A CG  1 
ATOM   2310 C CD1 . PHE A 1 362 ? 120.785 119.171 109.196 1.00 37.43  ? 343 PHE A CD1 1 
ATOM   2311 C CD2 . PHE A 1 362 ? 120.480 118.257 111.358 1.00 37.43  ? 343 PHE A CD2 1 
ATOM   2312 C CE1 . PHE A 1 362 ? 119.467 118.923 108.905 1.00 37.43  ? 343 PHE A CE1 1 
ATOM   2313 C CE2 . PHE A 1 362 ? 119.163 118.004 111.071 1.00 37.43  ? 343 PHE A CE2 1 
ATOM   2314 C CZ  . PHE A 1 362 ? 118.656 118.338 109.843 1.00 37.43  ? 343 PHE A CZ  1 
ATOM   2315 N N   . PHE A 1 363 ? 125.874 118.279 110.343 1.00 44.06  ? 344 PHE A N   1 
ATOM   2316 C CA  . PHE A 1 363 ? 127.273 118.494 110.694 1.00 44.06  ? 344 PHE A CA  1 
ATOM   2317 C C   . PHE A 1 363 ? 128.052 119.021 109.498 1.00 44.06  ? 344 PHE A C   1 
ATOM   2318 O O   . PHE A 1 363 ? 128.673 120.089 109.562 1.00 44.06  ? 344 PHE A O   1 
ATOM   2319 C CB  . PHE A 1 363 ? 127.880 117.191 111.211 1.00 44.06  ? 344 PHE A CB  1 
ATOM   2320 C CG  . PHE A 1 363 ? 129.301 117.315 111.645 1.00 44.06  ? 344 PHE A CG  1 
ATOM   2321 C CD1 . PHE A 1 363 ? 129.672 118.245 112.589 1.00 44.06  ? 344 PHE A CD1 1 
ATOM   2322 C CD2 . PHE A 1 363 ? 130.269 116.496 111.106 1.00 44.06  ? 344 PHE A CD2 1 
ATOM   2323 C CE1 . PHE A 1 363 ? 130.981 118.351 112.986 1.00 44.06  ? 344 PHE A CE1 1 
ATOM   2324 C CE2 . PHE A 1 363 ? 131.578 116.602 111.499 1.00 44.06  ? 344 PHE A CE2 1 
ATOM   2325 C CZ  . PHE A 1 363 ? 131.935 117.530 112.439 1.00 44.06  ? 344 PHE A CZ  1 
ATOM   2326 N N   . VAL A 1 364 ? 128.034 118.272 108.394 1.00 44.09  ? 345 VAL A N   1 
ATOM   2327 C CA  . VAL A 1 364 ? 128.645 118.756 107.156 1.00 44.09  ? 345 VAL A CA  1 
ATOM   2328 C C   . VAL A 1 364 ? 128.090 120.124 106.790 1.00 44.09  ? 345 VAL A C   1 
ATOM   2329 O O   . VAL A 1 364 ? 128.794 120.968 106.225 1.00 44.09  ? 345 VAL A O   1 
ATOM   2330 C CB  . VAL A 1 364 ? 128.434 117.746 106.017 1.00 44.09  ? 345 VAL A CB  1 
ATOM   2331 C CG1 . VAL A 1 364 ? 129.263 118.136 104.816 1.00 44.09  ? 345 VAL A CG1 1 
ATOM   2332 C CG2 . VAL A 1 364 ? 128.812 116.383 106.479 1.00 44.09  ? 345 VAL A CG2 1 
ATOM   2333 N N   . GLY A 1 365 ? 126.821 120.365 107.110 1.00 48.73  ? 346 GLY A N   1 
ATOM   2334 C CA  . GLY A 1 365 ? 126.240 121.666 106.835 1.00 48.73  ? 346 GLY A CA  1 
ATOM   2335 C C   . GLY A 1 365 ? 126.955 122.780 107.564 1.00 48.73  ? 346 GLY A C   1 
ATOM   2336 O O   . GLY A 1 365 ? 127.396 123.755 106.955 1.00 48.73  ? 346 GLY A O   1 
ATOM   2337 N N   . SER A 1 366 ? 127.083 122.647 108.876 1.00 55.36  ? 347 SER A N   1 
ATOM   2338 C CA  . SER A 1 366 ? 127.802 123.643 109.652 1.00 55.36  ? 347 SER A CA  1 
ATOM   2339 C C   . SER A 1 366 ? 129.275 123.714 109.289 1.00 55.36  ? 347 SER A C   1 
ATOM   2340 O O   . SER A 1 366 ? 129.903 124.753 109.510 1.00 55.36  ? 347 SER A O   1 
ATOM   2341 C CB  . SER A 1 366 ? 127.670 123.350 111.141 1.00 55.36  ? 347 SER A CB  1 
ATOM   2342 O OG  . SER A 1 366 ? 128.152 124.434 111.910 1.00 55.36  ? 347 SER A OG  1 
ATOM   2343 N N   . ARG A 1 367 ? 129.839 122.639 108.741 1.00 54.05  ? 348 ARG A N   1 
ATOM   2344 C CA  . ARG A 1 367 ? 131.256 122.652 108.406 1.00 54.05  ? 348 ARG A CA  1 
ATOM   2345 C C   . ARG A 1 367 ? 131.548 123.473 107.158 1.00 54.05  ? 348 ARG A C   1 
ATOM   2346 O O   . ARG A 1 367 ? 132.601 124.114 107.080 1.00 54.05  ? 348 ARG A O   1 
ATOM   2347 C CB  . ARG A 1 367 ? 131.764 121.226 108.222 1.00 54.05  ? 348 ARG A CB  1 
ATOM   2348 C CG  . ARG A 1 367 ? 133.256 121.086 108.400 1.00 54.05  ? 348 ARG A CG  1 
ATOM   2349 C CD  . ARG A 1 367 ? 133.667 119.636 108.314 1.00 54.05  ? 348 ARG A CD  1 
ATOM   2350 N NE  . ARG A 1 367 ? 133.324 119.066 107.019 1.00 54.05  ? 348 ARG A NE  1 
ATOM   2351 C CZ  . ARG A 1 367 ? 133.482 117.787 106.705 1.00 54.05  ? 348 ARG A CZ  1 
ATOM   2352 N NH1 . ARG A 1 367 ? 133.975 116.941 107.596 1.00 54.05  ? 348 ARG A NH1 1 
ATOM   2353 N NH2 . ARG A 1 367 ? 133.146 117.355 105.501 1.00 54.05  ? 348 ARG A NH2 1 
ATOM   2354 N N   . GLU A 1 368 ? 130.642 123.474 106.182 1.00 57.99  ? 349 GLU A N   1 
ATOM   2355 C CA  . GLU A 1 368 ? 130.868 124.188 104.932 1.00 57.99  ? 349 GLU A CA  1 
ATOM   2356 C C   . GLU A 1 368 ? 130.522 125.668 105.011 1.00 57.99  ? 349 GLU A C   1 
ATOM   2357 O O   . GLU A 1 368 ? 130.876 126.418 104.096 1.00 57.99  ? 349 GLU A O   1 
ATOM   2358 C CB  . GLU A 1 368 ? 130.064 123.542 103.798 1.00 57.99  ? 349 GLU A CB  1 
ATOM   2359 C CG  . GLU A 1 368 ? 130.314 122.055 103.621 1.00 57.99  ? 349 GLU A CG  1 
ATOM   2360 C CD  . GLU A 1 368 ? 131.614 121.747 102.904 1.00 57.99  ? 349 GLU A CD  1 
ATOM   2361 O OE1 . GLU A 1 368 ? 131.824 120.572 102.541 1.00 57.99  ? 349 GLU A OE1 1 
ATOM   2362 O OE2 . GLU A 1 368 ? 132.425 122.673 102.695 1.00 57.99  ? 349 GLU A OE2 1 
ATOM   2363 N N   . GLY A 1 369 ? 129.847 126.104 106.066 1.00 60.34  ? 350 GLY A N   1 
ATOM   2364 C CA  . GLY A 1 369 ? 129.539 127.500 106.256 1.00 60.34  ? 350 GLY A CA  1 
ATOM   2365 C C   . GLY A 1 369 ? 128.085 127.885 106.115 1.00 60.34  ? 350 GLY A C   1 
ATOM   2366 O O   . GLY A 1 369 ? 127.747 129.044 106.373 1.00 60.34  ? 350 GLY A O   1 
ATOM   2367 N N   . HIS A 1 370 ? 127.216 126.957 105.727 1.00 56.95  ? 351 HIS A N   1 
ATOM   2368 C CA  . HIS A 1 370 ? 125.800 127.242 105.557 1.00 56.95  ? 351 HIS A CA  1 
ATOM   2369 C C   . HIS A 1 370 ? 125.051 127.410 106.867 1.00 56.95  ? 351 HIS A C   1 
ATOM   2370 O O   . HIS A 1 370 ? 124.357 128.414 107.039 1.00 56.95  ? 351 HIS A O   1 
ATOM   2371 C CB  . HIS A 1 370 ? 125.125 126.131 104.740 1.00 56.95  ? 351 HIS A CB  1 
ATOM   2372 C CG  . HIS A 1 370 ? 125.599 126.051 103.324 1.00 56.95  ? 351 HIS A CG  1 
ATOM   2373 N ND1 . HIS A 1 370 ? 125.684 124.863 102.633 1.00 56.95  ? 351 HIS A ND1 1 
ATOM   2374 C CD2 . HIS A 1 370 ? 126.014 127.014 102.468 1.00 56.95  ? 351 HIS A CD2 1 
ATOM   2375 C CE1 . HIS A 1 370 ? 126.131 125.096 101.412 1.00 56.95  ? 351 HIS A CE1 1 
ATOM   2376 N NE2 . HIS A 1 370 ? 126.339 126.394 101.286 1.00 56.95  ? 351 HIS A NE2 1 
ATOM   2377 N N   . LEU A 1 371 ? 125.176 126.465 107.792 1.00 52.77  ? 352 LEU A N   1 
ATOM   2378 C CA  . LEU A 1 371 ? 124.576 126.556 109.110 1.00 52.77  ? 352 LEU A CA  1 
ATOM   2379 C C   . LEU A 1 371 ? 125.610 127.062 110.108 1.00 52.77  ? 352 LEU A C   1 
ATOM   2380 O O   . LEU A 1 371 ? 126.810 126.852 109.910 1.00 52.77  ? 352 LEU A O   1 
ATOM   2381 C CB  . LEU A 1 371 ? 124.040 125.193 109.560 1.00 52.77  ? 352 LEU A CB  1 
ATOM   2382 C CG  . LEU A 1 371 ? 122.655 124.849 109.024 1.00 52.77  ? 352 LEU A CG  1 
ATOM   2383 C CD1 . LEU A 1 371 ? 122.494 123.354 108.911 1.00 52.77  ? 352 LEU A CD1 1 
ATOM   2384 C CD2 . LEU A 1 371 ? 121.595 125.435 109.927 1.00 52.77  ? 352 LEU A CD2 1 
ATOM   2385 N N   . PRO A 1 372 ? 125.179 127.747 111.184 1.00 60.40  ? 353 PRO A N   1 
ATOM   2386 C CA  . PRO A 1 372 ? 126.143 128.337 112.125 1.00 60.40  ? 353 PRO A CA  1 
ATOM   2387 C C   . PRO A 1 372 ? 127.192 127.347 112.598 1.00 60.40  ? 353 PRO A C   1 
ATOM   2388 O O   . PRO A 1 372 ? 126.908 126.152 112.719 1.00 60.40  ? 353 PRO A O   1 
ATOM   2389 C CB  . PRO A 1 372 ? 125.256 128.811 113.284 1.00 60.40  ? 353 PRO A CB  1 
ATOM   2390 C CG  . PRO A 1 372 ? 123.991 128.038 113.140 1.00 60.40  ? 353 PRO A CG  1 
ATOM   2391 C CD  . PRO A 1 372 ? 123.799 127.892 111.669 1.00 60.40  ? 353 PRO A CD  1 
ATOM   2392 N N   . ASP A 1 373 ? 128.407 127.831 112.857 1.00 66.58  ? 354 ASP A N   1 
ATOM   2393 C CA  . ASP A 1 373 ? 129.537 126.963 113.171 1.00 66.58  ? 354 ASP A CA  1 
ATOM   2394 C C   . ASP A 1 373 ? 129.257 126.075 114.377 1.00 66.58  ? 354 ASP A C   1 
ATOM   2395 O O   . ASP A 1 373 ? 129.916 125.045 114.558 1.00 66.58  ? 354 ASP A O   1 
ATOM   2396 C CB  . ASP A 1 373 ? 130.799 127.795 113.407 1.00 66.58  ? 354 ASP A CB  1 
ATOM   2397 C CG  . ASP A 1 373 ? 131.665 127.902 112.165 1.00 66.58  ? 354 ASP A CG  1 
ATOM   2398 O OD1 . ASP A 1 373 ? 131.209 127.479 111.082 1.00 66.58  ? 354 ASP A OD1 1 
ATOM   2399 O OD2 . ASP A 1 373 ? 132.801 128.409 112.271 1.00 66.58  ? 354 ASP A OD2 1 
ATOM   2400 N N   . LEU A 1 374 ? 128.276 126.462 115.198 1.00 67.34  ? 355 LEU A N   1 
ATOM   2401 C CA  . LEU A 1 374 ? 127.913 125.657 116.360 1.00 67.34  ? 355 LEU A CA  1 
ATOM   2402 C C   . LEU A 1 374 ? 127.660 124.204 115.986 1.00 67.34  ? 355 LEU A C   1 
ATOM   2403 O O   . LEU A 1 374 ? 128.231 123.294 116.596 1.00 67.34  ? 355 LEU A O   1 
ATOM   2404 C CB  . LEU A 1 374 ? 126.678 126.235 117.045 1.00 67.34  ? 355 LEU A CB  1 
ATOM   2405 C CG  . LEU A 1 374 ? 125.978 125.209 117.941 1.00 67.34  ? 355 LEU A CG  1 
ATOM   2406 C CD1 . LEU A 1 374 ? 126.861 124.841 119.127 1.00 67.34  ? 355 LEU A CD1 1 
ATOM   2407 C CD2 . LEU A 1 374 ? 124.617 125.707 118.403 1.00 67.34  ? 355 LEU A CD2 1 
ATOM   2408 N N   . LEU A 1 375 ? 126.817 123.962 114.980 1.00 53.73  ? 356 LEU A N   1 
ATOM   2409 C CA  . LEU A 1 375 ? 126.435 122.589 114.665 1.00 53.73  ? 356 LEU A CA  1 
ATOM   2410 C C   . LEU A 1 375 ? 127.632 121.753 114.235 1.00 53.73  ? 356 LEU A C   1 
ATOM   2411 O O   . LEU A 1 375 ? 127.501 120.540 114.041 1.00 53.73  ? 356 LEU A O   1 
ATOM   2412 C CB  . LEU A 1 375 ? 125.361 122.566 113.579 1.00 53.73  ? 356 LEU A CB  1 
ATOM   2413 C CG  . LEU A 1 375 ? 124.101 123.411 113.764 1.00 53.73  ? 356 LEU A CG  1 
ATOM   2414 C CD1 . LEU A 1 375 ? 122.990 122.868 112.894 1.00 53.73  ? 356 LEU A CD1 1 
ATOM   2415 C CD2 . LEU A 1 375 ? 123.660 123.458 115.212 1.00 53.73  ? 356 LEU A CD2 1 
ATOM   2416 N N   . SER A 1 376 ? 128.800 122.370 114.084 1.00 61.31  ? 357 SER A N   1 
ATOM   2417 C CA  . SER A 1 376 ? 130.012 121.655 113.720 1.00 61.31  ? 357 SER A CA  1 
ATOM   2418 C C   . SER A 1 376 ? 130.824 121.203 114.925 1.00 61.31  ? 357 SER A C   1 
ATOM   2419 O O   . SER A 1 376 ? 131.874 120.581 114.746 1.00 61.31  ? 357 SER A O   1 
ATOM   2420 C CB  . SER A 1 376 ? 130.884 122.526 112.812 1.00 61.31  ? 357 SER A CB  1 
ATOM   2421 O OG  . SER A 1 376 ? 132.012 121.806 112.350 1.00 61.31  ? 357 SER A OG  1 
ATOM   2422 N N   . MET A 1 377 ? 130.379 121.504 116.141 1.00 69.32  ? 358 MET A N   1 
ATOM   2423 C CA  . MET A 1 377 ? 131.202 121.212 117.304 1.00 69.32  ? 358 MET A CA  1 
ATOM   2424 C C   . MET A 1 377 ? 131.215 119.715 117.598 1.00 69.32  ? 358 MET A C   1 
ATOM   2425 O O   . MET A 1 377 ? 130.450 118.936 117.029 1.00 69.32  ? 358 MET A O   1 
ATOM   2426 C CB  . MET A 1 377 ? 130.706 121.986 118.526 1.00 69.32  ? 358 MET A CB  1 
ATOM   2427 C CG  . MET A 1 377 ? 130.726 123.502 118.381 1.00 69.32  ? 358 MET A CG  1 
ATOM   2428 S SD  . MET A 1 377 ? 132.307 124.173 117.844 1.00 69.32  ? 358 MET A SD  1 
ATOM   2429 C CE  . MET A 1 377 ? 131.895 125.906 117.684 1.00 69.32  ? 358 MET A CE  1 
ATOM   2430 N N   . ILE A 1 378 ? 132.105 119.322 118.507 1.00 67.55  ? 359 ILE A N   1 
ATOM   2431 C CA  . ILE A 1 378 ? 132.307 117.927 118.888 1.00 67.55  ? 359 ILE A CA  1 
ATOM   2432 C C   . ILE A 1 378 ? 132.718 117.887 120.351 1.00 67.55  ? 359 ILE A C   1 
ATOM   2433 O O   . ILE A 1 378 ? 133.592 118.650 120.773 1.00 67.55  ? 359 ILE A O   1 
ATOM   2434 C CB  . ILE A 1 378 ? 133.382 117.233 118.028 1.00 67.55  ? 359 ILE A CB  1 
ATOM   2435 C CG1 . ILE A 1 378 ? 132.928 117.093 116.580 1.00 67.55  ? 359 ILE A CG1 1 
ATOM   2436 C CG2 . ILE A 1 378 ? 133.729 115.877 118.597 1.00 67.55  ? 359 ILE A CG2 1 
ATOM   2437 C CD1 . ILE A 1 378 ? 134.015 116.622 115.662 1.00 67.55  ? 359 ILE A CD1 1 
ATOM   2438 N N   . HIS A 1 379 ? 132.093 117.004 121.125 1.00 74.23  ? 360 HIS A N   1 
ATOM   2439 C CA  . HIS A 1 379 ? 132.458 116.841 122.527 1.00 74.23  ? 360 HIS A CA  1 
ATOM   2440 C C   . HIS A 1 379 ? 133.908 116.393 122.643 1.00 74.23  ? 360 HIS A C   1 
ATOM   2441 O O   . HIS A 1 379 ? 134.349 115.493 121.923 1.00 74.23  ? 360 HIS A O   1 
ATOM   2442 C CB  . HIS A 1 379 ? 131.523 115.837 123.195 1.00 74.23  ? 360 HIS A CB  1 
ATOM   2443 C CG  . HIS A 1 379 ? 131.600 115.835 124.691 1.00 74.23  ? 360 HIS A CG  1 
ATOM   2444 N ND1 . HIS A 1 379 ? 132.693 115.352 125.378 1.00 74.23  ? 360 HIS A ND1 1 
ATOM   2445 C CD2 . HIS A 1 379 ? 130.719 116.249 125.631 1.00 74.23  ? 360 HIS A CD2 1 
ATOM   2446 C CE1 . HIS A 1 379 ? 132.482 115.472 126.676 1.00 74.23  ? 360 HIS A CE1 1 
ATOM   2447 N NE2 . HIS A 1 379 ? 131.292 116.014 126.857 1.00 74.23  ? 360 HIS A NE2 1 
ATOM   2448 N N   . ILE A 1 380 ? 134.651 117.034 123.547 1.00 76.27  ? 361 ILE A N   1 
ATOM   2449 C CA  . ILE A 1 380 ? 136.085 116.799 123.653 1.00 76.27  ? 361 ILE A CA  1 
ATOM   2450 C C   . ILE A 1 380 ? 136.403 115.394 124.134 1.00 76.27  ? 361 ILE A C   1 
ATOM   2451 O O   . ILE A 1 380 ? 137.336 114.763 123.628 1.00 76.27  ? 361 ILE A O   1 
ATOM   2452 C CB  . ILE A 1 380 ? 136.733 117.836 124.594 1.00 76.27  ? 361 ILE A CB  1 
ATOM   2453 C CG1 . ILE A 1 380 ? 136.575 119.250 124.044 1.00 76.27  ? 361 ILE A CG1 1 
ATOM   2454 C CG2 . ILE A 1 380 ? 138.199 117.520 124.810 1.00 76.27  ? 361 ILE A CG2 1 
ATOM   2455 C CD1 . ILE A 1 380 ? 135.369 119.980 124.574 1.00 76.27  ? 361 ILE A CD1 1 
ATOM   2456 N N   . GLU A 1 381 ? 135.641 114.875 125.093 1.00 77.46  ? 362 GLU A N   1 
ATOM   2457 C CA  . GLU A 1 381 ? 136.030 113.671 125.817 1.00 77.46  ? 362 GLU A CA  1 
ATOM   2458 C C   . GLU A 1 381 ? 135.403 112.408 125.238 1.00 77.46  ? 362 GLU A C   1 
ATOM   2459 O O   . GLU A 1 381 ? 135.837 111.297 125.556 1.00 77.46  ? 362 GLU A O   1 
ATOM   2460 C CB  . GLU A 1 381 ? 135.662 113.826 127.298 1.00 77.46  ? 362 GLU A CB  1 
ATOM   2461 C CG  . GLU A 1 381 ? 136.466 114.893 128.022 1.00 77.46  ? 362 GLU A CG  1 
ATOM   2462 C CD  . GLU A 1 381 ? 135.648 115.640 129.057 1.00 77.46  ? 362 GLU A CD  1 
ATOM   2463 O OE1 . GLU A 1 381 ? 134.508 115.214 129.339 1.00 77.46  ? 362 GLU A OE1 1 
ATOM   2464 O OE2 . GLU A 1 381 ? 136.144 116.657 129.587 1.00 77.46  ? 362 GLU A OE2 1 
ATOM   2465 N N   . ARG A 1 382 ? 134.382 112.554 124.396 1.00 66.39  ? 363 ARG A N   1 
ATOM   2466 C CA  . ARG A 1 382 ? 133.667 111.392 123.887 1.00 66.39  ? 363 ARG A CA  1 
ATOM   2467 C C   . ARG A 1 382 ? 133.541 111.370 122.367 1.00 66.39  ? 363 ARG A C   1 
ATOM   2468 O O   . ARG A 1 382 ? 133.161 110.334 121.814 1.00 66.39  ? 363 ARG A O   1 
ATOM   2469 C CB  . ARG A 1 382 ? 132.292 111.332 124.548 1.00 66.39  ? 363 ARG A CB  1 
ATOM   2470 C CG  . ARG A 1 382 ? 131.437 112.534 124.249 1.00 66.39  ? 363 ARG A CG  1 
ATOM   2471 C CD  . ARG A 1 382 ? 130.166 112.545 125.070 1.00 66.39  ? 363 ARG A CD  1 
ATOM   2472 N NE  . ARG A 1 382 ? 130.441 112.677 126.496 1.00 66.39  ? 363 ARG A NE  1 
ATOM   2473 C CZ  . ARG A 1 382 ? 130.284 111.696 127.379 1.00 66.39  ? 363 ARG A CZ  1 
ATOM   2474 N NH1 . ARG A 1 382 ? 129.852 110.508 126.980 1.00 66.39  ? 363 ARG A NH1 1 
ATOM   2475 N NH2 . ARG A 1 382 ? 130.557 111.902 128.659 1.00 66.39  ? 363 ARG A NH2 1 
ATOM   2476 N N   . PHE A 1 383 ? 133.849 112.473 121.686 1.00 62.11  ? 364 PHE A N   1 
ATOM   2477 C CA  . PHE A 1 383 ? 133.913 112.567 120.228 1.00 62.11  ? 364 PHE A CA  1 
ATOM   2478 C C   . PHE A 1 383 ? 132.597 112.229 119.541 1.00 62.11  ? 364 PHE A C   1 
ATOM   2479 O O   . PHE A 1 383 ? 132.559 111.319 118.706 1.00 62.11  ? 364 PHE A O   1 
ATOM   2480 C CB  . PHE A 1 383 ? 135.028 111.687 119.656 1.00 62.11  ? 364 PHE A CB  1 
ATOM   2481 C CG  . PHE A 1 383 ? 136.384 112.011 120.194 1.00 62.11  ? 364 PHE A CG  1 
ATOM   2482 C CD1 . PHE A 1 383 ? 136.786 113.323 120.342 1.00 62.11  ? 364 PHE A CD1 1 
ATOM   2483 C CD2 . PHE A 1 383 ? 137.256 111.005 120.557 1.00 62.11  ? 364 PHE A CD2 1 
ATOM   2484 C CE1 . PHE A 1 383 ? 138.034 113.625 120.839 1.00 62.11  ? 364 PHE A CE1 1 
ATOM   2485 C CE2 . PHE A 1 383 ? 138.504 111.302 121.056 1.00 62.11  ? 364 PHE A CE2 1 
ATOM   2486 C CZ  . PHE A 1 383 ? 138.893 112.614 121.197 1.00 62.11  ? 364 PHE A CZ  1 
ATOM   2487 N N   . THR A 1 384 ? 131.519 112.933 119.866 1.00 53.09  ? 365 THR A N   1 
ATOM   2488 C CA  . THR A 1 384 ? 130.205 112.818 119.245 1.00 53.09  ? 365 THR A CA  1 
ATOM   2489 C C   . THR A 1 384 ? 129.653 114.204 118.930 1.00 53.09  ? 365 THR A C   1 
ATOM   2490 O O   . THR A 1 384 ? 129.699 115.094 119.782 1.00 53.09  ? 365 THR A O   1 
ATOM   2491 C CB  . THR A 1 384 ? 129.234 112.100 120.166 1.00 53.09  ? 365 THR A CB  1 
ATOM   2492 O OG1 . THR A 1 384 ? 129.025 112.896 121.335 1.00 53.09  ? 365 THR A OG1 1 
ATOM   2493 C CG2 . THR A 1 384 ? 129.784 110.754 120.578 1.00 53.09  ? 365 THR A CG2 1 
ATOM   2494 N N   . PRO A 1 385 ? 129.101 114.428 117.740 1.00 41.13  ? 366 PRO A N   1 
ATOM   2495 C CA  . PRO A 1 385 ? 128.658 115.779 117.387 1.00 41.13  ? 366 PRO A CA  1 
ATOM   2496 C C   . PRO A 1 385 ? 127.431 116.180 118.177 1.00 41.13  ? 366 PRO A C   1 
ATOM   2497 O O   . PRO A 1 385 ? 126.305 116.089 117.685 1.00 41.13  ? 366 PRO A O   1 
ATOM   2498 C CB  . PRO A 1 385 ? 128.360 115.669 115.891 1.00 41.13  ? 366 PRO A CB  1 
ATOM   2499 C CG  . PRO A 1 385 ? 127.970 114.271 115.708 1.00 41.13  ? 366 PRO A CG  1 
ATOM   2500 C CD  . PRO A 1 385 ? 128.751 113.452 116.698 1.00 41.13  ? 366 PRO A CD  1 
ATOM   2501 N N   . ILE A 1 386 ? 127.651 116.614 119.417 1.00 45.49  ? 367 ILE A N   1 
ATOM   2502 C CA  . ILE A 1 386 ? 126.532 116.933 120.302 1.00 45.49  ? 367 ILE A CA  1 
ATOM   2503 C C   . ILE A 1 386 ? 125.616 118.003 119.723 1.00 45.49  ? 367 ILE A C   1 
ATOM   2504 O O   . ILE A 1 386 ? 124.416 117.732 119.565 1.00 45.49  ? 367 ILE A O   1 
ATOM   2505 C CB  . ILE A 1 386 ? 127.052 117.290 121.706 1.00 45.49  ? 367 ILE A CB  1 
ATOM   2506 C CG1 . ILE A 1 386 ? 127.442 116.018 122.449 1.00 45.49  ? 367 ILE A CG1 1 
ATOM   2507 C CG2 . ILE A 1 386 ? 126.007 118.066 122.474 1.00 45.49  ? 367 ILE A CG2 1 
ATOM   2508 C CD1 . ILE A 1 386 ? 127.966 116.267 123.826 1.00 45.49  ? 367 ILE A CD1 1 
ATOM   2509 N N   . PRO A 1 387 ? 126.084 119.210 119.398 1.00 40.16  ? 368 PRO A N   1 
ATOM   2510 C CA  . PRO A 1 387 ? 125.132 120.251 118.985 1.00 40.16  ? 368 PRO A CA  1 
ATOM   2511 C C   . PRO A 1 387 ? 124.302 119.883 117.769 1.00 40.16  ? 368 PRO A C   1 
ATOM   2512 O O   . PRO A 1 387 ? 123.125 120.253 117.707 1.00 40.16  ? 368 PRO A O   1 
ATOM   2513 C CB  . PRO A 1 387 ? 126.036 121.455 118.711 1.00 40.16  ? 368 PRO A CB  1 
ATOM   2514 C CG  . PRO A 1 387 ? 127.349 120.870 118.429 1.00 40.16  ? 368 PRO A CG  1 
ATOM   2515 C CD  . PRO A 1 387 ? 127.468 119.698 119.327 1.00 40.16  ? 368 PRO A CD  1 
ATOM   2516 N N   . ALA A 1 388 ? 124.861 119.154 116.804 1.00 34.30  ? 369 ALA A N   1 
ATOM   2517 C CA  . ALA A 1 388 ? 124.042 118.706 115.682 1.00 34.30  ? 369 ALA A CA  1 
ATOM   2518 C C   . ALA A 1 388 ? 122.956 117.753 116.156 1.00 34.30  ? 369 ALA A C   1 
ATOM   2519 O O   . ALA A 1 388 ? 121.814 117.809 115.684 1.00 34.30  ? 369 ALA A O   1 
ATOM   2520 C CB  . ALA A 1 388 ? 124.914 118.044 114.619 1.00 34.30  ? 369 ALA A CB  1 
ATOM   2521 N N   . LEU A 1 389 ? 123.285 116.892 117.119 1.00 31.29  ? 370 LEU A N   1 
ATOM   2522 C CA  . LEU A 1 389 ? 122.302 115.958 117.651 1.00 31.29  ? 370 LEU A CA  1 
ATOM   2523 C C   . LEU A 1 389 ? 121.192 116.689 118.389 1.00 31.29  ? 370 LEU A C   1 
ATOM   2524 O O   . LEU A 1 389 ? 120.017 116.332 118.263 1.00 31.29  ? 370 LEU A O   1 
ATOM   2525 C CB  . LEU A 1 389 ? 122.990 114.958 118.570 1.00 31.29  ? 370 LEU A CB  1 
ATOM   2526 C CG  . LEU A 1 389 ? 123.567 113.761 117.834 1.00 31.29  ? 370 LEU A CG  1 
ATOM   2527 C CD1 . LEU A 1 389 ? 124.266 112.845 118.793 1.00 31.29  ? 370 LEU A CD1 1 
ATOM   2528 C CD2 . LEU A 1 389 ? 122.449 113.039 117.163 1.00 31.29  ? 370 LEU A CD2 1 
ATOM   2529 N N   . LEU A 1 390 ? 121.544 117.715 119.165 1.00 34.97  ? 371 LEU A N   1 
ATOM   2530 C CA  . LEU A 1 390 ? 120.523 118.492 119.859 1.00 34.97  ? 371 LEU A CA  1 
ATOM   2531 C C   . LEU A 1 390 ? 119.666 119.272 118.875 1.00 34.97  ? 371 LEU A C   1 
ATOM   2532 O O   . LEU A 1 390 ? 118.457 119.415 119.077 1.00 34.97  ? 371 LEU A O   1 
ATOM   2533 C CB  . LEU A 1 390 ? 121.165 119.438 120.870 1.00 34.97  ? 371 LEU A CB  1 
ATOM   2534 C CG  . LEU A 1 390 ? 121.989 118.789 121.975 1.00 34.97  ? 371 LEU A CG  1 
ATOM   2535 C CD1 . LEU A 1 390 ? 122.215 119.777 123.101 1.00 34.97  ? 371 LEU A CD1 1 
ATOM   2536 C CD2 . LEU A 1 390 ? 121.310 117.534 122.483 1.00 34.97  ? 371 LEU A CD2 1 
ATOM   2537 N N   . PHE A 1 391 ? 120.267 119.776 117.797 1.00 35.06  ? 372 PHE A N   1 
ATOM   2538 C CA  . PHE A 1 391 ? 119.473 120.453 116.780 1.00 35.06  ? 372 PHE A CA  1 
ATOM   2539 C C   . PHE A 1 391 ? 118.480 119.497 116.138 1.00 35.06  ? 372 PHE A C   1 
ATOM   2540 O O   . PHE A 1 391 ? 117.321 119.858 115.907 1.00 35.06  ? 372 PHE A O   1 
ATOM   2541 C CB  . PHE A 1 391 ? 120.379 121.073 115.721 1.00 35.06  ? 372 PHE A CB  1 
ATOM   2542 C CG  . PHE A 1 391 ? 119.685 122.068 114.843 1.00 35.06  ? 372 PHE A CG  1 
ATOM   2543 C CD1 . PHE A 1 391 ? 118.891 121.651 113.794 1.00 35.06  ? 372 PHE A CD1 1 
ATOM   2544 C CD2 . PHE A 1 391 ? 119.828 123.424 115.067 1.00 35.06  ? 372 PHE A CD2 1 
ATOM   2545 C CE1 . PHE A 1 391 ? 118.250 122.565 112.989 1.00 35.06  ? 372 PHE A CE1 1 
ATOM   2546 C CE2 . PHE A 1 391 ? 119.187 124.346 114.263 1.00 35.06  ? 372 PHE A CE2 1 
ATOM   2547 C CZ  . PHE A 1 391 ? 118.398 123.915 113.223 1.00 35.06  ? 372 PHE A CZ  1 
ATOM   2548 N N   . ASN A 1 392 ? 118.903 118.262 115.867 1.00 31.24  ? 373 ASN A N   1 
ATOM   2549 C CA  . ASN A 1 392 ? 117.984 117.316 115.243 1.00 31.24  ? 373 ASN A CA  1 
ATOM   2550 C C   . ASN A 1 392 ? 116.893 116.874 116.212 1.00 31.24  ? 373 ASN A C   1 
ATOM   2551 O O   . ASN A 1 392 ? 115.730 116.724 115.819 1.00 31.24  ? 373 ASN A O   1 
ATOM   2552 C CB  . ASN A 1 392 ? 118.736 116.104 114.716 1.00 31.24  ? 373 ASN A CB  1 
ATOM   2553 C CG  . ASN A 1 392 ? 117.823 115.128 114.036 1.00 31.24  ? 373 ASN A CG  1 
ATOM   2554 O OD1 . ASN A 1 392 ? 117.570 115.233 112.841 1.00 31.24  ? 373 ASN A OD1 1 
ATOM   2555 N ND2 . ASN A 1 392 ? 117.302 114.180 114.796 1.00 31.24  ? 373 ASN A ND2 1 
ATOM   2556 N N   . CYS A 1 393 ? 117.246 116.649 117.478 1.00 34.80  ? 374 CYS A N   1 
ATOM   2557 C CA  . CYS A 1 393 ? 116.232 116.327 118.475 1.00 34.80  ? 374 CYS A CA  1 
ATOM   2558 C C   . CYS A 1 393 ? 115.219 117.453 118.614 1.00 34.80  ? 374 CYS A C   1 
ATOM   2559 O O   . CYS A 1 393 ? 114.012 117.203 118.697 1.00 34.80  ? 374 CYS A O   1 
ATOM   2560 C CB  . CYS A 1 393 ? 116.887 116.036 119.822 1.00 34.80  ? 374 CYS A CB  1 
ATOM   2561 S SG  . CYS A 1 393 ? 115.748 116.102 121.217 1.00 34.80  ? 374 CYS A SG  1 
ATOM   2562 N N   . THR A 1 394 ? 115.688 118.701 118.650 1.00 30.50  ? 375 THR A N   1 
ATOM   2563 C CA  . THR A 1 394 ? 114.768 119.825 118.759 1.00 30.50  ? 375 THR A CA  1 
ATOM   2564 C C   . THR A 1 394 ? 113.882 119.929 117.528 1.00 30.50  ? 375 THR A C   1 
ATOM   2565 O O   . THR A 1 394 ? 112.684 120.199 117.647 1.00 30.50  ? 375 THR A O   1 
ATOM   2566 C CB  . THR A 1 394 ? 115.542 121.121 118.977 1.00 30.50  ? 375 THR A CB  1 
ATOM   2567 O OG1 . THR A 1 394 ? 116.269 121.038 120.206 1.00 30.50  ? 375 THR A OG1 1 
ATOM   2568 C CG2 . THR A 1 394 ? 114.597 122.294 119.047 1.00 30.50  ? 375 THR A CG2 1 
ATOM   2569 N N   . MET A 1 395 ? 114.439 119.695 116.339 1.00 34.89  ? 376 MET A N   1 
ATOM   2570 C CA  . MET A 1 395 ? 113.614 119.716 115.136 1.00 34.89  ? 376 MET A CA  1 
ATOM   2571 C C   . MET A 1 395 ? 112.528 118.651 115.196 1.00 34.89  ? 376 MET A C   1 
ATOM   2572 O O   . MET A 1 395 ? 111.358 118.930 114.905 1.00 34.89  ? 376 MET A O   1 
ATOM   2573 C CB  . MET A 1 395 ? 114.479 119.523 113.892 1.00 34.89  ? 376 MET A CB  1 
ATOM   2574 C CG  . MET A 1 395 ? 115.055 120.803 113.329 1.00 34.89  ? 376 MET A CG  1 
ATOM   2575 S SD  . MET A 1 395 ? 113.948 122.211 113.502 1.00 34.89  ? 376 MET A SD  1 
ATOM   2576 C CE  . MET A 1 395 ? 112.622 121.747 112.393 1.00 34.89  ? 376 MET A CE  1 
ATOM   2577 N N   . ALA A 1 396 ? 112.891 117.425 115.573 1.00 29.47  ? 377 ALA A N   1 
ATOM   2578 C CA  . ALA A 1 396 ? 111.899 116.359 115.630 1.00 29.47  ? 377 ALA A CA  1 
ATOM   2579 C C   . ALA A 1 396 ? 110.817 116.663 116.658 1.00 29.47  ? 377 ALA A C   1 
ATOM   2580 O O   . ALA A 1 396 ? 109.623 116.523 116.371 1.00 29.47  ? 377 ALA A O   1 
ATOM   2581 C CB  . ALA A 1 396 ? 112.575 115.028 115.938 1.00 29.47  ? 377 ALA A CB  1 
ATOM   2582 N N   . LEU A 1 397 ? 111.211 117.088 117.860 1.00 29.97  ? 378 LEU A N   1 
ATOM   2583 C CA  . LEU A 1 397 ? 110.218 117.400 118.882 1.00 29.97  ? 378 LEU A CA  1 
ATOM   2584 C C   . LEU A 1 397 ? 109.327 118.563 118.472 1.00 29.97  ? 378 LEU A C   1 
ATOM   2585 O O   . LEU A 1 397 ? 108.140 118.577 118.812 1.00 29.97  ? 378 LEU A O   1 
ATOM   2586 C CB  . LEU A 1 397 ? 110.899 117.707 120.211 1.00 29.97  ? 378 LEU A CB  1 
ATOM   2587 C CG  . LEU A 1 397 ? 111.625 116.532 120.852 1.00 29.97  ? 378 LEU A CG  1 
ATOM   2588 C CD1 . LEU A 1 397 ? 112.004 116.864 122.275 1.00 29.97  ? 378 LEU A CD1 1 
ATOM   2589 C CD2 . LEU A 1 397 ? 110.754 115.307 120.802 1.00 29.97  ? 378 LEU A CD2 1 
ATOM   2590 N N   . ILE A 1 398 ? 109.871 119.547 117.754 1.00 33.57  ? 379 ILE A N   1 
ATOM   2591 C CA  . ILE A 1 398 ? 109.036 120.627 117.239 1.00 33.57  ? 379 ILE A CA  1 
ATOM   2592 C C   . ILE A 1 398 ? 108.025 120.081 116.243 1.00 33.57  ? 379 ILE A C   1 
ATOM   2593 O O   . ILE A 1 398 ? 106.839 120.424 116.290 1.00 33.57  ? 379 ILE A O   1 
ATOM   2594 C CB  . ILE A 1 398 ? 109.904 121.732 116.615 1.00 33.57  ? 379 ILE A CB  1 
ATOM   2595 C CG1 . ILE A 1 398 ? 110.631 122.514 117.707 1.00 33.57  ? 379 ILE A CG1 1 
ATOM   2596 C CG2 . ILE A 1 398 ? 109.056 122.664 115.780 1.00 33.57  ? 379 ILE A CG2 1 
ATOM   2597 C CD1 . ILE A 1 398 ? 109.705 123.176 118.697 1.00 33.57  ? 379 ILE A CD1 1 
ATOM   2598 N N   . TYR A 1 399 ? 108.469 119.211 115.340 1.00 36.86  ? 380 TYR A N   1 
ATOM   2599 C CA  . TYR A 1 399 ? 107.554 118.630 114.366 1.00 36.86  ? 380 TYR A CA  1 
ATOM   2600 C C   . TYR A 1 399 ? 106.753 117.466 114.924 1.00 36.86  ? 380 TYR A C   1 
ATOM   2601 O O   . TYR A 1 399 ? 106.113 116.752 114.145 1.00 36.86  ? 380 TYR A O   1 
ATOM   2602 C CB  . TYR A 1 399 ? 108.313 118.176 113.123 1.00 36.86  ? 380 TYR A CB  1 
ATOM   2603 C CG  . TYR A 1 399 ? 108.342 119.222 112.045 1.00 36.86  ? 380 TYR A CG  1 
ATOM   2604 C CD1 . TYR A 1 399 ? 109.248 120.266 112.093 1.00 36.86  ? 380 TYR A CD1 1 
ATOM   2605 C CD2 . TYR A 1 399 ? 107.455 119.175 110.988 1.00 36.86  ? 380 TYR A CD2 1 
ATOM   2606 C CE1 . TYR A 1 399 ? 109.277 121.228 111.113 1.00 36.86  ? 380 TYR A CE1 1 
ATOM   2607 C CE2 . TYR A 1 399 ? 107.475 120.131 110.003 1.00 36.86  ? 380 TYR A CE2 1 
ATOM   2608 C CZ  . TYR A 1 399 ? 108.388 121.157 110.070 1.00 36.86  ? 380 TYR A CZ  1 
ATOM   2609 O OH  . TYR A 1 399 ? 108.411 122.118 109.087 1.00 36.86  ? 380 TYR A OH  1 
ATOM   2610 N N   . LEU A 1 400 ? 106.788 117.243 116.237 1.00 35.54  ? 381 LEU A N   1 
ATOM   2611 C CA  . LEU A 1 400 ? 105.824 116.348 116.862 1.00 35.54  ? 381 LEU A CA  1 
ATOM   2612 C C   . LEU A 1 400 ? 104.565 117.070 117.312 1.00 35.54  ? 381 LEU A C   1 
ATOM   2613 O O   . LEU A 1 400 ? 103.525 116.425 117.463 1.00 35.54  ? 381 LEU A O   1 
ATOM   2614 C CB  . LEU A 1 400 ? 106.445 115.635 118.063 1.00 35.54  ? 381 LEU A CB  1 
ATOM   2615 C CG  . LEU A 1 400 ? 106.916 114.216 117.779 1.00 35.54  ? 381 LEU A CG  1 
ATOM   2616 C CD1 . LEU A 1 400 ? 107.366 113.538 119.049 1.00 35.54  ? 381 LEU A CD1 1 
ATOM   2617 C CD2 . LEU A 1 400 ? 105.790 113.455 117.154 1.00 35.54  ? 381 LEU A CD2 1 
ATOM   2618 N N   . ILE A 1 401 ? 104.634 118.385 117.529 1.00 43.26  ? 382 ILE A N   1 
ATOM   2619 C CA  . ILE A 1 401 ? 103.453 119.112 117.981 1.00 43.26  ? 382 ILE A CA  1 
ATOM   2620 C C   . ILE A 1 401 ? 102.360 119.071 116.924 1.00 43.26  ? 382 ILE A C   1 
ATOM   2621 O O   . ILE A 1 401 ? 101.169 119.116 117.252 1.00 43.26  ? 382 ILE A O   1 
ATOM   2622 C CB  . ILE A 1 401 ? 103.814 120.562 118.363 1.00 43.26  ? 382 ILE A CB  1 
ATOM   2623 C CG1 . ILE A 1 401 ? 104.023 121.423 117.117 1.00 43.26  ? 382 ILE A CG1 1 
ATOM   2624 C CG2 . ILE A 1 401 ? 105.060 120.590 119.234 1.00 43.26  ? 382 ILE A CG2 1 
ATOM   2625 C CD1 . ILE A 1 401 ? 104.119 122.900 117.404 1.00 43.26  ? 382 ILE A CD1 1 
ATOM   2626 N N   . VAL A 1 402 ? 102.737 118.984 115.649 1.00 48.55  ? 383 VAL A N   1 
ATOM   2627 C CA  . VAL A 1 402 ? 101.759 118.997 114.571 1.00 48.55  ? 383 VAL A CA  1 
ATOM   2628 C C   . VAL A 1 402 ? 100.896 117.748 114.651 1.00 48.55  ? 383 VAL A C   1 
ATOM   2629 O O   . VAL A 1 402 ? 101.400 116.632 114.829 1.00 48.55  ? 383 VAL A O   1 
ATOM   2630 C CB  . VAL A 1 402 ? 102.462 119.104 113.211 1.00 48.55  ? 383 VAL A CB  1 
ATOM   2631 C CG1 . VAL A 1 402 ? 101.467 118.928 112.085 1.00 48.55  ? 383 VAL A CG1 1 
ATOM   2632 C CG2 . VAL A 1 402 ? 103.159 120.445 113.085 1.00 48.55  ? 383 VAL A CG2 1 
ATOM   2633 N N   . GLU A 1 403 ? 99.585  117.933 114.538 1.00 63.38  ? 384 GLU A N   1 
ATOM   2634 C CA  . GLU A 1 403 ? 98.684  116.800 114.413 1.00 63.38  ? 384 GLU A CA  1 
ATOM   2635 C C   . GLU A 1 403 ? 98.724  116.266 112.990 1.00 63.38  ? 384 GLU A C   1 
ATOM   2636 O O   . GLU A 1 403 ? 98.714  117.033 112.024 1.00 63.38  ? 384 GLU A O   1 
ATOM   2637 C CB  . GLU A 1 403 ? 97.258  117.205 114.777 1.00 63.38  ? 384 GLU A CB  1 
ATOM   2638 C CG  . GLU A 1 403 ? 96.231  116.112 114.534 1.00 63.38  ? 384 GLU A CG  1 
ATOM   2639 C CD  . GLU A 1 403 ? 94.834  116.657 114.322 1.00 63.38  ? 384 GLU A CD  1 
ATOM   2640 O OE1 . GLU A 1 403 ? 94.012  115.956 113.696 1.00 63.38  ? 384 GLU A OE1 1 
ATOM   2641 O OE2 . GLU A 1 403 ? 94.558  117.786 114.777 1.00 63.38  ? 384 GLU A OE2 1 
ATOM   2642 N N   . ASP A 1 404 ? 98.777  114.940 112.865 1.00 65.01  ? 385 ASP A N   1 
ATOM   2643 C CA  . ASP A 1 404 ? 98.751  114.264 111.569 1.00 65.01  ? 385 ASP A CA  1 
ATOM   2644 C C   . ASP A 1 404 ? 99.920  114.737 110.697 1.00 65.01  ? 385 ASP A C   1 
ATOM   2645 O O   . ASP A 1 404 ? 99.761  115.422 109.686 1.00 65.01  ? 385 ASP A O   1 
ATOM   2646 C CB  . ASP A 1 404 ? 97.387  114.474 110.894 1.00 65.01  ? 385 ASP A CB  1 
ATOM   2647 C CG  . ASP A 1 404 ? 97.289  113.819 109.528 1.00 65.01  ? 385 ASP A CG  1 
ATOM   2648 O OD1 . ASP A 1 404 ? 97.605  114.481 108.518 1.00 65.01  ? 385 ASP A OD1 1 
ATOM   2649 O OD2 . ASP A 1 404 ? 96.844  112.654 109.462 1.00 65.01  ? 385 ASP A OD2 1 
ATOM   2650 N N   . VAL A 1 405 ? 101.124 114.395 111.168 1.00 58.25  ? 386 VAL A N   1 
ATOM   2651 C CA  . VAL A 1 405 ? 102.329 114.611 110.370 1.00 58.25  ? 386 VAL A CA  1 
ATOM   2652 C C   . VAL A 1 405 ? 102.474 113.590 109.257 1.00 58.25  ? 386 VAL A C   1 
ATOM   2653 O O   . VAL A 1 405 ? 103.317 113.772 108.370 1.00 58.25  ? 386 VAL A O   1 
ATOM   2654 C CB  . VAL A 1 405 ? 103.607 114.588 111.229 1.00 58.25  ? 386 VAL A CB  1 
ATOM   2655 C CG1 . VAL A 1 405 ? 103.600 115.735 112.208 1.00 58.25  ? 386 VAL A CG1 1 
ATOM   2656 C CG2 . VAL A 1 405 ? 103.727 113.273 111.957 1.00 58.25  ? 386 VAL A CG2 1 
ATOM   2657 N N   . PHE A 1 406 ? 101.670 112.524 109.269 1.00 58.93  ? 387 PHE A N   1 
ATOM   2658 C CA  . PHE A 1 406 ? 101.707 111.548 108.188 1.00 58.93  ? 387 PHE A CA  1 
ATOM   2659 C C   . PHE A 1 406 ? 101.360 112.165 106.843 1.00 58.93  ? 387 PHE A C   1 
ATOM   2660 O O   . PHE A 1 406 ? 101.648 111.562 105.805 1.00 58.93  ? 387 PHE A O   1 
ATOM   2661 C CB  . PHE A 1 406 ? 100.744 110.398 108.470 1.00 58.93  ? 387 PHE A CB  1 
ATOM   2662 C CG  . PHE A 1 406 ? 101.055 109.634 109.719 1.00 58.93  ? 387 PHE A CG  1 
ATOM   2663 C CD1 . PHE A 1 406 ? 100.668 110.111 110.956 1.00 58.93  ? 387 PHE A CD1 1 
ATOM   2664 C CD2 . PHE A 1 406 ? 101.716 108.422 109.652 1.00 58.93  ? 387 PHE A CD2 1 
ATOM   2665 C CE1 . PHE A 1 406 ? 100.945 109.401 112.098 1.00 58.93  ? 387 PHE A CE1 1 
ATOM   2666 C CE2 . PHE A 1 406 ? 101.995 107.710 110.792 1.00 58.93  ? 387 PHE A CE2 1 
ATOM   2667 C CZ  . PHE A 1 406 ? 101.608 108.199 112.014 1.00 58.93  ? 387 PHE A CZ  1 
ATOM   2668 N N   . GLN A 1 407 ? 100.740 113.346 106.837 1.00 66.11  ? 388 GLN A N   1 
ATOM   2669 C CA  . GLN A 1 407 ? 100.422 114.003 105.577 1.00 66.11  ? 388 GLN A CA  1 
ATOM   2670 C C   . GLN A 1 407 ? 101.640 114.707 104.999 1.00 66.11  ? 388 GLN A C   1 
ATOM   2671 O O   . GLN A 1 407 ? 101.702 114.943 103.786 1.00 66.11  ? 388 GLN A O   1 
ATOM   2672 C CB  . GLN A 1 407 ? 99.272  114.990 105.778 1.00 66.11  ? 388 GLN A CB  1 
ATOM   2673 C CG  . GLN A 1 407 ? 98.689  115.561 104.496 1.00 66.11  ? 388 GLN A CG  1 
ATOM   2674 C CD  . GLN A 1 407 ? 99.235  116.937 104.170 1.00 66.11  ? 388 GLN A CD  1 
ATOM   2675 O OE1 . GLN A 1 407 ? 100.264 117.350 104.700 1.00 66.11  ? 388 GLN A OE1 1 
ATOM   2676 N NE2 . GLN A 1 407 ? 98.542  117.657 103.299 1.00 66.11  ? 388 GLN A NE2 1 
ATOM   2677 N N   . LEU A 1 408 ? 102.628 115.026 105.835 1.00 61.69  ? 389 LEU A N   1 
ATOM   2678 C CA  . LEU A 1 408 ? 103.813 115.701 105.326 1.00 61.69  ? 389 LEU A CA  1 
ATOM   2679 C C   . LEU A 1 408 ? 104.672 114.803 104.446 1.00 61.69  ? 389 LEU A C   1 
ATOM   2680 O O   . LEU A 1 408 ? 105.691 115.272 103.934 1.00 61.69  ? 389 LEU A O   1 
ATOM   2681 C CB  . LEU A 1 408 ? 104.649 116.255 106.479 1.00 61.69  ? 389 LEU A CB  1 
ATOM   2682 C CG  . LEU A 1 408 ? 104.033 117.422 107.251 1.00 61.69  ? 389 LEU A CG  1 
ATOM   2683 C CD1 . LEU A 1 408 ? 104.975 117.912 108.331 1.00 61.69  ? 389 LEU A CD1 1 
ATOM   2684 C CD2 . LEU A 1 408 ? 103.675 118.548 106.315 1.00 61.69  ? 389 LEU A CD2 1 
ATOM   2685 N N   . ILE A 1 409 ? 104.285 113.545 104.238 1.00 62.01  ? 390 ILE A N   1 
ATOM   2686 C CA  . ILE A 1 409 ? 104.970 112.680 103.283 1.00 62.01  ? 390 ILE A CA  1 
ATOM   2687 C C   . ILE A 1 409 ? 104.565 113.117 101.881 1.00 62.01  ? 390 ILE A C   1 
ATOM   2688 O O   . ILE A 1 409 ? 105.054 112.585 100.879 1.00 62.01  ? 390 ILE A O   1 
ATOM   2689 C CB  . ILE A 1 409 ? 104.644 111.194 103.526 1.00 62.01  ? 390 ILE A CB  1 
ATOM   2690 C CG1 . ILE A 1 409 ? 104.863 110.832 104.988 1.00 62.01  ? 390 ILE A CG1 1 
ATOM   2691 C CG2 . ILE A 1 409 ? 105.537 110.289 102.695 1.00 62.01  ? 390 ILE A CG2 1 
ATOM   2692 C CD1 . ILE A 1 409 ? 104.630 109.367 105.288 1.00 62.01  ? 390 ILE A CD1 1 
ATOM   2693 N N   . ASN A 1 410 ? 103.677 114.102 101.795 1.00 67.83  ? 391 ASN A N   1 
ATOM   2694 C CA  . ASN A 1 410 ? 103.269 114.628 100.504 1.00 67.83  ? 391 ASN A CA  1 
ATOM   2695 C C   . ASN A 1 410 ? 104.107 115.817 100.054 1.00 67.83  ? 391 ASN A C   1 
ATOM   2696 O O   . ASN A 1 410 ? 104.061 116.172 98.873  1.00 67.83  ? 391 ASN A O   1 
ATOM   2697 C CB  . ASN A 1 410 ? 101.793 115.032 100.540 1.00 67.83  ? 391 ASN A CB  1 
ATOM   2698 C CG  . ASN A 1 410 ? 100.882 113.881 100.911 1.00 67.83  ? 391 ASN A CG  1 
ATOM   2699 O OD1 . ASN A 1 410 ? 99.737  114.087 101.311 1.00 67.83  ? 391 ASN A OD1 1 
ATOM   2700 N ND2 . ASN A 1 410 ? 101.384 112.660 100.777 1.00 67.83  ? 391 ASN A ND2 1 
ATOM   2701 N N   . TYR A 1 411 ? 104.871 116.435 100.955 1.00 67.21  ? 392 TYR A N   1 
ATOM   2702 C CA  . TYR A 1 411 ? 105.631 117.626 100.605 1.00 67.21  ? 392 TYR A CA  1 
ATOM   2703 C C   . TYR A 1 411 ? 107.091 117.349 100.284 1.00 67.21  ? 392 TYR A C   1 
ATOM   2704 O O   . TYR A 1 411 ? 107.756 118.223 99.720  1.00 67.21  ? 392 TYR A O   1 
ATOM   2705 C CB  . TYR A 1 411 ? 105.569 118.656 101.738 1.00 67.21  ? 392 TYR A CB  1 
ATOM   2706 C CG  . TYR A 1 411 ? 104.198 119.230 101.978 1.00 67.21  ? 392 TYR A CG  1 
ATOM   2707 C CD1 . TYR A 1 411 ? 103.170 119.020 101.078 1.00 67.21  ? 392 TYR A CD1 1 
ATOM   2708 C CD2 . TYR A 1 411 ? 103.936 119.994 103.099 1.00 67.21  ? 392 TYR A CD2 1 
ATOM   2709 C CE1 . TYR A 1 411 ? 101.918 119.541 101.296 1.00 67.21  ? 392 TYR A CE1 1 
ATOM   2710 C CE2 . TYR A 1 411 ? 102.688 120.521 103.325 1.00 67.21  ? 392 TYR A CE2 1 
ATOM   2711 C CZ  . TYR A 1 411 ? 101.682 120.292 102.421 1.00 67.21  ? 392 TYR A CZ  1 
ATOM   2712 O OH  . TYR A 1 411 ? 100.433 120.818 102.642 1.00 67.21  ? 392 TYR A OH  1 
ATOM   2713 N N   . PHE A 1 412 ? 107.612 116.173 100.626 1.00 60.65  ? 393 PHE A N   1 
ATOM   2714 C CA  . PHE A 1 412 ? 108.993 115.847 100.308 1.00 60.65  ? 393 PHE A CA  1 
ATOM   2715 C C   . PHE A 1 412 ? 109.132 114.641 99.394  1.00 60.65  ? 393 PHE A C   1 
ATOM   2716 O O   . PHE A 1 412 ? 110.262 114.280 99.046  1.00 60.65  ? 393 PHE A O   1 
ATOM   2717 C CB  . PHE A 1 412 ? 109.812 115.624 101.589 1.00 60.65  ? 393 PHE A CB  1 
ATOM   2718 C CG  . PHE A 1 412 ? 109.362 114.457 102.424 1.00 60.65  ? 393 PHE A CG  1 
ATOM   2719 C CD1 . PHE A 1 412 ? 109.714 113.163 102.087 1.00 60.65  ? 393 PHE A CD1 1 
ATOM   2720 C CD2 . PHE A 1 412 ? 108.633 114.661 103.574 1.00 60.65  ? 393 PHE A CD2 1 
ATOM   2721 C CE1 . PHE A 1 412 ? 109.315 112.098 102.862 1.00 60.65  ? 393 PHE A CE1 1 
ATOM   2722 C CE2 . PHE A 1 412 ? 108.234 113.599 104.352 1.00 60.65  ? 393 PHE A CE2 1 
ATOM   2723 C CZ  . PHE A 1 412 ? 108.575 112.318 103.997 1.00 60.65  ? 393 PHE A CZ  1 
ATOM   2724 N N   . SER A 1 413 ? 108.029 114.007 98.993  1.00 61.73  ? 394 SER A N   1 
ATOM   2725 C CA  . SER A 1 413 ? 108.127 112.897 98.057  1.00 61.73  ? 394 SER A CA  1 
ATOM   2726 C C   . SER A 1 413 ? 108.472 113.358 96.650  1.00 61.73  ? 394 SER A C   1 
ATOM   2727 O O   . SER A 1 413 ? 108.660 112.514 95.768  1.00 61.73  ? 394 SER A O   1 
ATOM   2728 C CB  . SER A 1 413 ? 106.824 112.101 98.040  1.00 61.73  ? 394 SER A CB  1 
ATOM   2729 O OG  . SER A 1 413 ? 106.784 111.181 99.117  1.00 61.73  ? 394 SER A OG  1 
ATOM   2730 N N   . PHE A 1 414 ? 108.554 114.665 96.422  1.00 60.51  ? 395 PHE A N   1 
ATOM   2731 C CA  . PHE A 1 414 ? 109.188 115.203 95.229  1.00 60.51  ? 395 PHE A CA  1 
ATOM   2732 C C   . PHE A 1 414 ? 110.540 115.830 95.525  1.00 60.51  ? 395 PHE A C   1 
ATOM   2733 O O   . PHE A 1 414 ? 111.341 116.012 94.611  1.00 60.51  ? 395 PHE A O   1 
ATOM   2734 C CB  . PHE A 1 414 ? 108.297 116.250 94.559  1.00 60.51  ? 395 PHE A CB  1 
ATOM   2735 C CG  . PHE A 1 414 ? 108.980 116.983 93.445  1.00 60.51  ? 395 PHE A CG  1 
ATOM   2736 C CD1 . PHE A 1 414 ? 109.285 116.336 92.264  1.00 60.51  ? 395 PHE A CD1 1 
ATOM   2737 C CD2 . PHE A 1 414 ? 109.356 118.300 93.592  1.00 60.51  ? 395 PHE A CD2 1 
ATOM   2738 C CE1 . PHE A 1 414 ? 109.925 116.999 91.242  1.00 60.51  ? 395 PHE A CE1 1 
ATOM   2739 C CE2 . PHE A 1 414 ? 109.998 118.962 92.574  1.00 60.51  ? 395 PHE A CE2 1 
ATOM   2740 C CZ  . PHE A 1 414 ? 110.280 118.315 91.399  1.00 60.51  ? 395 PHE A CZ  1 
ATOM   2741 N N   . SER A 1 415 ? 110.822 116.160 96.785  1.00 59.81  ? 396 SER A N   1 
ATOM   2742 C CA  . SER A 1 415 ? 112.104 116.779 97.103  1.00 59.81  ? 396 SER A CA  1 
ATOM   2743 C C   . SER A 1 415 ? 113.179 115.731 97.358  1.00 59.81  ? 396 SER A C   1 
ATOM   2744 O O   . SER A 1 415 ? 114.299 115.849 96.846  1.00 59.81  ? 396 SER A O   1 
ATOM   2745 C CB  . SER A 1 415 ? 111.956 117.707 98.305  1.00 59.81  ? 396 SER A CB  1 
ATOM   2746 O OG  . SER A 1 415 ? 111.493 118.982 97.900  1.00 59.81  ? 396 SER A OG  1 
ATOM   2747 N N   . TYR A 1 416 ? 112.858 114.700 98.142  1.00 60.78  ? 397 TYR A N   1 
ATOM   2748 C CA  . TYR A 1 416 ? 113.836 113.657 98.437  1.00 60.78  ? 397 TYR A CA  1 
ATOM   2749 C C   . TYR A 1 416 ? 114.371 113.029 97.156  1.00 60.78  ? 397 TYR A C   1 
ATOM   2750 O O   . TYR A 1 416 ? 115.589 112.964 96.941  1.00 60.78  ? 397 TYR A O   1 
ATOM   2751 C CB  . TYR A 1 416 ? 113.209 112.594 99.338  1.00 60.78  ? 397 TYR A CB  1 
ATOM   2752 C CG  . TYR A 1 416 ? 114.102 111.407 99.623  1.00 60.78  ? 397 TYR A CG  1 
ATOM   2753 C CD1 . TYR A 1 416 ? 115.482 111.542 99.669  1.00 60.78  ? 397 TYR A CD1 1 
ATOM   2754 C CD2 . TYR A 1 416 ? 113.565 110.148 99.843  1.00 60.78  ? 397 TYR A CD2 1 
ATOM   2755 C CE1 . TYR A 1 416 ? 116.300 110.458 99.922  1.00 60.78  ? 397 TYR A CE1 1 
ATOM   2756 C CE2 . TYR A 1 416 ? 114.377 109.056 100.099 1.00 60.78  ? 397 TYR A CE2 1 
ATOM   2757 C CZ  . TYR A 1 416 ? 115.745 109.218 100.137 1.00 60.78  ? 397 TYR A CZ  1 
ATOM   2758 O OH  . TYR A 1 416 ? 116.566 108.144 100.392 1.00 60.78  ? 397 TYR A OH  1 
ATOM   2759 N N   . TRP A 1 417 ? 113.476 112.562 96.288  1.00 54.87  ? 398 TRP A N   1 
ATOM   2760 C CA  . TRP A 1 417 ? 113.952 111.868 95.103  1.00 54.87  ? 398 TRP A CA  1 
ATOM   2761 C C   . TRP A 1 417 ? 114.474 112.828 94.051  1.00 54.87  ? 398 TRP A C   1 
ATOM   2762 O O   . TRP A 1 417 ? 115.360 112.454 93.278  1.00 54.87  ? 398 TRP A O   1 
ATOM   2763 C CB  . TRP A 1 417 ? 112.860 110.970 94.539  1.00 54.87  ? 398 TRP A CB  1 
ATOM   2764 C CG  . TRP A 1 417 ? 112.827 109.685 95.274  1.00 54.87  ? 398 TRP A CG  1 
ATOM   2765 C CD1 . TRP A 1 417 ? 112.024 109.368 96.319  1.00 54.87  ? 398 TRP A CD1 1 
ATOM   2766 C CD2 . TRP A 1 417 ? 113.685 108.560 95.071  1.00 54.87  ? 398 TRP A CD2 1 
ATOM   2767 N NE1 . TRP A 1 417 ? 112.302 108.100 96.764  1.00 54.87  ? 398 TRP A NE1 1 
ATOM   2768 C CE2 . TRP A 1 417 ? 113.322 107.584 96.012  1.00 54.87  ? 398 TRP A CE2 1 
ATOM   2769 C CE3 . TRP A 1 417 ? 114.715 108.279 94.173  1.00 54.87  ? 398 TRP A CE3 1 
ATOM   2770 C CZ2 . TRP A 1 417 ? 113.949 106.348 96.084  1.00 54.87  ? 398 TRP A CZ2 1 
ATOM   2771 C CZ3 . TRP A 1 417 ? 115.336 107.051 94.244  1.00 54.87  ? 398 TRP A CZ3 1 
ATOM   2772 C CH2 . TRP A 1 417 ? 114.952 106.101 95.191  1.00 54.87  ? 398 TRP A CH2 1 
ATOM   2773 N N   . PHE A 1 418 ? 113.989 114.069 94.027  1.00 51.22  ? 399 PHE A N   1 
ATOM   2774 C CA  . PHE A 1 418 ? 114.640 115.063 93.185  1.00 51.22  ? 399 PHE A CA  1 
ATOM   2775 C C   . PHE A 1 418 ? 116.094 115.224 93.578  1.00 51.22  ? 399 PHE A C   1 
ATOM   2776 O O   . PHE A 1 418 ? 116.968 115.321 92.715  1.00 51.22  ? 399 PHE A O   1 
ATOM   2777 C CB  . PHE A 1 418 ? 113.930 116.409 93.270  1.00 51.22  ? 399 PHE A CB  1 
ATOM   2778 C CG  . PHE A 1 418 ? 114.643 117.517 92.555  1.00 51.22  ? 399 PHE A CG  1 
ATOM   2779 C CD1 . PHE A 1 418 ? 115.112 117.341 91.270  1.00 51.22  ? 399 PHE A CD1 1 
ATOM   2780 C CD2 . PHE A 1 418 ? 114.842 118.737 93.170  1.00 51.22  ? 399 PHE A CD2 1 
ATOM   2781 C CE1 . PHE A 1 418 ? 115.765 118.359 90.615  1.00 51.22  ? 399 PHE A CE1 1 
ATOM   2782 C CE2 . PHE A 1 418 ? 115.494 119.758 92.518  1.00 51.22  ? 399 PHE A CE2 1 
ATOM   2783 C CZ  . PHE A 1 418 ? 115.956 119.568 91.240  1.00 51.22  ? 399 PHE A CZ  1 
ATOM   2784 N N   . PHE A 1 419 ? 116.382 115.216 94.877  1.00 51.52  ? 400 PHE A N   1 
ATOM   2785 C CA  . PHE A 1 419 ? 117.755 115.460 95.294  1.00 51.52  ? 400 PHE A CA  1 
ATOM   2786 C C   . PHE A 1 419 ? 118.631 114.228 95.117  1.00 51.52  ? 400 PHE A C   1 
ATOM   2787 O O   . PHE A 1 419 ? 119.814 114.356 94.791  1.00 51.52  ? 400 PHE A O   1 
ATOM   2788 C CB  . PHE A 1 419 ? 117.777 115.963 96.728  1.00 51.52  ? 400 PHE A CB  1 
ATOM   2789 C CG  . PHE A 1 419 ? 117.544 117.426 96.821  1.00 51.52  ? 400 PHE A CG  1 
ATOM   2790 C CD1 . PHE A 1 419 ? 118.262 118.288 96.020  1.00 51.52  ? 400 PHE A CD1 1 
ATOM   2791 C CD2 . PHE A 1 419 ? 116.577 117.943 97.653  1.00 51.52  ? 400 PHE A CD2 1 
ATOM   2792 C CE1 . PHE A 1 419 ? 118.046 119.640 96.075  1.00 51.52  ? 400 PHE A CE1 1 
ATOM   2793 C CE2 . PHE A 1 419 ? 116.356 119.297 97.705  1.00 51.52  ? 400 PHE A CE2 1 
ATOM   2794 C CZ  . PHE A 1 419 ? 117.091 120.145 96.920  1.00 51.52  ? 400 PHE A CZ  1 
ATOM   2795 N N   . VAL A 1 420 ? 118.076 113.030 95.301  1.00 53.52  ? 401 VAL A N   1 
ATOM   2796 C CA  . VAL A 1 420 ? 118.833 111.826 94.956  1.00 53.52  ? 401 VAL A CA  1 
ATOM   2797 C C   . VAL A 1 420 ? 119.170 111.820 93.468  1.00 53.52  ? 401 VAL A C   1 
ATOM   2798 O O   . VAL A 1 420 ? 120.318 111.573 93.066  1.00 53.52  ? 401 VAL A O   1 
ATOM   2799 C CB  . VAL A 1 420 ? 118.058 110.563 95.363  1.00 53.52  ? 401 VAL A CB  1 
ATOM   2800 C CG1 . VAL A 1 420 ? 118.637 109.358 94.668  1.00 53.52  ? 401 VAL A CG1 1 
ATOM   2801 C CG2 . VAL A 1 420 ? 118.114 110.383 96.861  1.00 53.52  ? 401 VAL A CG2 1 
ATOM   2802 N N   . GLY A 1 421 ? 118.179 112.113 92.624  1.00 56.92  ? 402 GLY A N   1 
ATOM   2803 C CA  . GLY A 1 421 ? 118.435 112.187 91.199  1.00 56.92  ? 402 GLY A CA  1 
ATOM   2804 C C   . GLY A 1 421 ? 119.414 113.278 90.827  1.00 56.92  ? 402 GLY A C   1 
ATOM   2805 O O   . GLY A 1 421 ? 120.200 113.119 89.891  1.00 56.92  ? 402 GLY A O   1 
ATOM   2806 N N   . LEU A 1 422 ? 119.392 114.394 91.551  1.00 54.37  ? 403 LEU A N   1 
ATOM   2807 C CA  . LEU A 1 422 ? 120.320 115.469 91.239  1.00 54.37  ? 403 LEU A CA  1 
ATOM   2808 C C   . LEU A 1 422 ? 121.727 115.130 91.694  1.00 54.37  ? 403 LEU A C   1 
ATOM   2809 O O   . LEU A 1 422 ? 122.695 115.551 91.061  1.00 54.37  ? 403 LEU A O   1 
ATOM   2810 C CB  . LEU A 1 422 ? 119.854 116.773 91.869  1.00 54.37  ? 403 LEU A CB  1 
ATOM   2811 C CG  . LEU A 1 422 ? 120.580 117.990 91.320  1.00 54.37  ? 403 LEU A CG  1 
ATOM   2812 C CD1 . LEU A 1 422 ? 120.523 117.950 89.820  1.00 54.37  ? 403 LEU A CD1 1 
ATOM   2813 C CD2 . LEU A 1 422 ? 119.889 119.221 91.810  1.00 54.37  ? 403 LEU A CD2 1 
ATOM   2814 N N   . SER A 1 423 ? 121.865 114.350 92.764  1.00 55.76  ? 404 SER A N   1 
ATOM   2815 C CA  . SER A 1 423 ? 123.180 113.830 93.116  1.00 55.76  ? 404 SER A CA  1 
ATOM   2816 C C   . SER A 1 423 ? 123.695 112.882 92.042  1.00 55.76  ? 404 SER A C   1 
ATOM   2817 O O   . SER A 1 423 ? 124.890 112.880 91.726  1.00 55.76  ? 404 SER A O   1 
ATOM   2818 C CB  . SER A 1 423 ? 123.124 113.127 94.467  1.00 55.76  ? 404 SER A CB  1 
ATOM   2819 O OG  . SER A 1 423 ? 124.202 112.223 94.598  1.00 55.76  ? 404 SER A OG  1 
ATOM   2820 N N   . VAL A 1 424 ? 122.807 112.075 91.460  1.00 61.03  ? 405 VAL A N   1 
ATOM   2821 C CA  . VAL A 1 424 ? 123.231 111.200 90.367  1.00 61.03  ? 405 VAL A CA  1 
ATOM   2822 C C   . VAL A 1 424 ? 123.665 112.022 89.154  1.00 61.03  ? 405 VAL A C   1 
ATOM   2823 O O   . VAL A 1 424 ? 124.699 111.742 88.527  1.00 61.03  ? 405 VAL A O   1 
ATOM   2824 C CB  . VAL A 1 424 ? 122.111 110.210 90.011  1.00 61.03  ? 405 VAL A CB  1 
ATOM   2825 C CG1 . VAL A 1 424 ? 122.368 109.593 88.652  1.00 61.03  ? 405 VAL A CG1 1 
ATOM   2826 C CG2 . VAL A 1 424 ? 122.003 109.136 91.074  1.00 61.03  ? 405 VAL A CG2 1 
ATOM   2827 N N   . VAL A 1 425 ? 122.878 113.038 88.793  1.00 58.75  ? 406 VAL A N   1 
ATOM   2828 C CA  . VAL A 1 425 ? 123.272 113.946 87.719  1.00 58.75  ? 406 VAL A CA  1 
ATOM   2829 C C   . VAL A 1 425 ? 124.602 114.613 88.043  1.00 58.75  ? 406 VAL A C   1 
ATOM   2830 O O   . VAL A 1 425 ? 125.419 114.851 87.149  1.00 58.75  ? 406 VAL A O   1 
ATOM   2831 C CB  . VAL A 1 425 ? 122.162 114.984 87.461  1.00 58.75  ? 406 VAL A CB  1 
ATOM   2832 C CG1 . VAL A 1 425 ? 122.644 116.070 86.517  1.00 58.75  ? 406 VAL A CG1 1 
ATOM   2833 C CG2 . VAL A 1 425 ? 120.934 114.304 86.896  1.00 58.75  ? 406 VAL A CG2 1 
ATOM   2834 N N   . GLY A 1 426 ? 124.846 114.915 89.318  1.00 64.26  ? 407 GLY A N   1 
ATOM   2835 C CA  . GLY A 1 426 ? 126.131 115.466 89.705  1.00 64.26  ? 407 GLY A CA  1 
ATOM   2836 C C   . GLY A 1 426 ? 127.264 114.484 89.497  1.00 64.26  ? 407 GLY A C   1 
ATOM   2837 O O   . GLY A 1 426 ? 128.365 114.867 89.097  1.00 64.26  ? 407 GLY A O   1 
ATOM   2838 N N   . GLN A 1 427 ? 127.011 113.204 89.761  1.00 67.64  ? 408 GLN A N   1 
ATOM   2839 C CA  . GLN A 1 427 ? 128.036 112.201 89.492  1.00 67.64  ? 408 GLN A CA  1 
ATOM   2840 C C   . GLN A 1 427 ? 128.345 112.130 88.004  1.00 67.64  ? 408 GLN A C   1 
ATOM   2841 O O   . GLN A 1 427 ? 129.507 111.987 87.608  1.00 67.64  ? 408 GLN A O   1 
ATOM   2842 C CB  . GLN A 1 427 ? 127.604 110.825 89.980  1.00 67.64  ? 408 GLN A CB  1 
ATOM   2843 C CG  . GLN A 1 427 ? 128.626 109.768 89.625  1.00 67.64  ? 408 GLN A CG  1 
ATOM   2844 C CD  . GLN A 1 427 ? 128.018 108.413 89.441  1.00 67.64  ? 408 GLN A CD  1 
ATOM   2845 O OE1 . GLN A 1 427 ? 126.815 108.245 89.577  1.00 67.64  ? 408 GLN A OE1 1 
ATOM   2846 N NE2 . GLN A 1 427 ? 128.845 107.431 89.122  1.00 67.64  ? 408 GLN A NE2 1 
ATOM   2847 N N   . LEU A 1 428 ? 127.313 112.208 87.165  1.00 68.56  ? 409 LEU A N   1 
ATOM   2848 C CA  . LEU A 1 428 ? 127.549 112.186 85.723  1.00 68.56  ? 409 LEU A CA  1 
ATOM   2849 C C   . LEU A 1 428 ? 128.304 113.432 85.271  1.00 68.56  ? 409 LEU A C   1 
ATOM   2850 O O   . LEU A 1 428 ? 129.196 113.355 84.416  1.00 68.56  ? 409 LEU A O   1 
ATOM   2851 C CB  . LEU A 1 428 ? 126.225 112.054 84.974  1.00 68.56  ? 409 LEU A CB  1 
ATOM   2852 C CG  . LEU A 1 428 ? 125.573 110.676 85.048  1.00 68.56  ? 409 LEU A CG  1 
ATOM   2853 C CD1 . LEU A 1 428 ? 124.202 110.699 84.404  1.00 68.56  ? 409 LEU A CD1 1 
ATOM   2854 C CD2 . LEU A 1 428 ? 126.461 109.646 84.385  1.00 68.56  ? 409 LEU A CD2 1 
ATOM   2855 N N   . TYR A 1 429 ? 127.945 114.588 85.831  1.00 75.52  ? 410 TYR A N   1 
ATOM   2856 C CA  . TYR A 1 429 ? 128.674 115.822 85.568  1.00 75.52  ? 410 TYR A CA  1 
ATOM   2857 C C   . TYR A 1 429 ? 130.144 115.673 85.931  1.00 75.52  ? 410 TYR A C   1 
ATOM   2858 O O   . TYR A 1 429 ? 131.023 116.137 85.198  1.00 75.52  ? 410 TYR A O   1 
ATOM   2859 C CB  . TYR A 1 429 ? 128.028 116.963 86.356  1.00 75.52  ? 410 TYR A CB  1 
ATOM   2860 C CG  . TYR A 1 429 ? 128.488 118.356 86.000  1.00 75.52  ? 410 TYR A CG  1 
ATOM   2861 C CD1 . TYR A 1 429 ? 129.740 118.817 86.374  1.00 75.52  ? 410 TYR A CD1 1 
ATOM   2862 C CD2 . TYR A 1 429 ? 127.649 119.226 85.325  1.00 75.52  ? 410 TYR A CD2 1 
ATOM   2863 C CE1 . TYR A 1 429 ? 130.152 120.092 86.061  1.00 75.52  ? 410 TYR A CE1 1 
ATOM   2864 C CE2 . TYR A 1 429 ? 128.051 120.503 85.008  1.00 75.52  ? 410 TYR A CE2 1 
ATOM   2865 C CZ  . TYR A 1 429 ? 129.303 120.932 85.379  1.00 75.52  ? 410 TYR A CZ  1 
ATOM   2866 O OH  . TYR A 1 429 ? 129.708 122.208 85.064  1.00 75.52  ? 410 TYR A OH  1 
ATOM   2867 N N   . LEU A 1 430 ? 130.428 115.032 87.065  1.00 78.25  ? 411 LEU A N   1 
ATOM   2868 C CA  . LEU A 1 430 ? 131.812 114.787 87.456  1.00 78.25  ? 411 LEU A CA  1 
ATOM   2869 C C   . LEU A 1 430 ? 132.505 113.855 86.473  1.00 78.25  ? 411 LEU A C   1 
ATOM   2870 O O   . LEU A 1 430 ? 133.630 114.126 86.038  1.00 78.25  ? 411 LEU A O   1 
ATOM   2871 C CB  . LEU A 1 430 ? 131.860 114.201 88.863  1.00 78.25  ? 411 LEU A CB  1 
ATOM   2872 C CG  . LEU A 1 430 ? 131.768 115.207 90.002  1.00 78.25  ? 411 LEU A CG  1 
ATOM   2873 C CD1 . LEU A 1 430 ? 131.493 114.490 91.309  1.00 78.25  ? 411 LEU A CD1 1 
ATOM   2874 C CD2 . LEU A 1 430 ? 133.050 116.010 90.083  1.00 78.25  ? 411 LEU A CD2 1 
ATOM   2875 N N   . ARG A 1 431 ? 131.850 112.745 86.125  1.00 85.26  ? 412 ARG A N   1 
ATOM   2876 C CA  . ARG A 1 431 ? 132.432 111.787 85.192  1.00 85.26  ? 412 ARG A CA  1 
ATOM   2877 C C   . ARG A 1 431 ? 132.802 112.453 83.875  1.00 85.26  ? 412 ARG A C   1 
ATOM   2878 O O   . ARG A 1 431 ? 133.854 112.157 83.297  1.00 85.26  ? 412 ARG A O   1 
ATOM   2879 C CB  . ARG A 1 431 ? 131.461 110.632 84.953  1.00 85.26  ? 412 ARG A CB  1 
ATOM   2880 C CG  . ARG A 1 431 ? 131.507 109.561 86.020  1.00 85.26  ? 412 ARG A CG  1 
ATOM   2881 C CD  . ARG A 1 431 ? 132.864 108.890 86.052  1.00 85.26  ? 412 ARG A CD  1 
ATOM   2882 N NE  . ARG A 1 431 ? 133.015 107.913 84.980  1.00 85.26  ? 412 ARG A NE  1 
ATOM   2883 C CZ  . ARG A 1 431 ? 132.645 106.641 85.073  1.00 85.26  ? 412 ARG A CZ  1 
ATOM   2884 N NH1 . ARG A 1 431 ? 132.098 106.188 86.192  1.00 85.26  ? 412 ARG A NH1 1 
ATOM   2885 N NH2 . ARG A 1 431 ? 132.821 105.820 84.048  1.00 85.26  ? 412 ARG A NH2 1 
ATOM   2886 N N   . TRP A 1 432 ? 131.953 113.356 83.384  1.00 90.84  ? 413 TRP A N   1 
ATOM   2887 C CA  . TRP A 1 432 ? 132.271 114.041 82.135  1.00 90.84  ? 413 TRP A CA  1 
ATOM   2888 C C   . TRP A 1 432 ? 133.370 115.076 82.338  1.00 90.84  ? 413 TRP A C   1 
ATOM   2889 O O   . TRP A 1 432 ? 134.402 115.043 81.658  1.00 90.84  ? 413 TRP A O   1 
ATOM   2890 C CB  . TRP A 1 432 ? 131.031 114.714 81.555  1.00 90.84  ? 413 TRP A CB  1 
ATOM   2891 C CG  . TRP A 1 432 ? 131.392 115.723 80.512  1.00 90.84  ? 413 TRP A CG  1 
ATOM   2892 C CD1 . TRP A 1 432 ? 131.963 115.474 79.300  1.00 90.84  ? 413 TRP A CD1 1 
ATOM   2893 C CD2 . TRP A 1 432 ? 131.251 117.145 80.604  1.00 90.84  ? 413 TRP A CD2 1 
ATOM   2894 N NE1 . TRP A 1 432 ? 132.166 116.650 78.621  1.00 90.84  ? 413 TRP A NE1 1 
ATOM   2895 C CE2 . TRP A 1 432 ? 131.738 117.691 79.401  1.00 90.84  ? 413 TRP A CE2 1 
ATOM   2896 C CE3 . TRP A 1 432 ? 130.751 118.009 81.581  1.00 90.84  ? 413 TRP A CE3 1 
ATOM   2897 C CZ2 . TRP A 1 432 ? 131.741 119.059 79.150  1.00 90.84  ? 413 TRP A CZ2 1 
ATOM   2898 C CZ3 . TRP A 1 432 ? 130.755 119.367 81.329  1.00 90.84  ? 413 TRP A CZ3 1 
ATOM   2899 C CH2 . TRP A 1 432 ? 131.246 119.879 80.125  1.00 90.84  ? 413 TRP A CH2 1 
ATOM   2900 N N   . LYS A 1 433 ? 133.162 116.007 83.270  1.00 88.45  ? 414 LYS A N   1 
ATOM   2901 C CA  . LYS A 1 433 ? 134.053 117.154 83.400  1.00 88.45  ? 414 LYS A CA  1 
ATOM   2902 C C   . LYS A 1 433 ? 135.425 116.743 83.912  1.00 88.45  ? 414 LYS A C   1 
ATOM   2903 O O   . LYS A 1 433 ? 136.449 117.060 83.295  1.00 88.45  ? 414 LYS A O   1 
ATOM   2904 C CB  . LYS A 1 433 ? 133.432 118.195 84.331  1.00 88.45  ? 414 LYS A CB  1 
ATOM   2905 C CG  . LYS A 1 433 ? 134.149 119.532 84.325  1.00 88.45  ? 414 LYS A CG  1 
ATOM   2906 C CD  . LYS A 1 433 ? 133.542 120.488 85.334  1.00 88.45  ? 414 LYS A CD  1 
ATOM   2907 C CE  . LYS A 1 433 ? 134.268 120.412 86.667  1.00 88.45  ? 414 LYS A CE  1 
ATOM   2908 N NZ  . LYS A 1 433 ? 133.700 121.357 87.668  1.00 88.45  ? 414 LYS A NZ  1 
ATOM   2909 N N   . GLU A 1 434 ? 135.469 116.043 85.045  1.00 90.44  ? 415 GLU A N   1 
ATOM   2910 C CA  . GLU A 1 434 ? 136.713 115.738 85.745  1.00 90.44  ? 415 GLU A CA  1 
ATOM   2911 C C   . GLU A 1 434 ? 136.872 114.223 85.789  1.00 90.44  ? 415 GLU A C   1 
ATOM   2912 O O   . GLU A 1 434 ? 136.508 113.575 86.782  1.00 90.44  ? 415 GLU A O   1 
ATOM   2913 C CB  . GLU A 1 434 ? 136.712 116.356 87.142  1.00 90.44  ? 415 GLU A CB  1 
ATOM   2914 C CG  . GLU A 1 434 ? 137.937 116.058 87.978  1.00 90.44  ? 415 GLU A CG  1 
ATOM   2915 C CD  . GLU A 1 434 ? 137.898 116.760 89.321  1.00 90.44  ? 415 GLU A CD  1 
ATOM   2916 O OE1 . GLU A 1 434 ? 136.918 117.488 89.582  1.00 90.44  ? 415 GLU A OE1 1 
ATOM   2917 O OE2 . GLU A 1 434 ? 138.842 116.578 90.119  1.00 90.44  ? 415 GLU A OE2 1 
ATOM   2918 N N   . PRO A 1 435 ? 137.392 113.618 84.718  1.00 93.28  ? 416 PRO A N   1 
ATOM   2919 C CA  . PRO A 1 435 ? 137.581 112.165 84.696  1.00 93.28  ? 416 PRO A CA  1 
ATOM   2920 C C   . PRO A 1 435 ? 138.887 111.702 85.313  1.00 93.28  ? 416 PRO A C   1 
ATOM   2921 O O   . PRO A 1 435 ? 139.193 110.507 85.243  1.00 93.28  ? 416 PRO A O   1 
ATOM   2922 C CB  . PRO A 1 435 ? 137.552 111.855 83.198  1.00 93.28  ? 416 PRO A CB  1 
ATOM   2923 C CG  . PRO A 1 435 ? 138.191 113.059 82.584  1.00 93.28  ? 416 PRO A CG  1 
ATOM   2924 C CD  . PRO A 1 435 ? 137.836 114.244 83.461  1.00 93.28  ? 416 PRO A CD  1 
ATOM   2925 N N   . LYS A 1 436 ? 139.663 112.605 85.905  1.00 91.94  ? 417 LYS A N   1 
ATOM   2926 C CA  . LYS A 1 436 ? 140.971 112.272 86.450  1.00 91.94  ? 417 LYS A CA  1 
ATOM   2927 C C   . LYS A 1 436 ? 140.977 112.217 87.972  1.00 91.94  ? 417 LYS A C   1 
ATOM   2928 O O   . LYS A 1 436 ? 142.054 112.155 88.572  1.00 91.94  ? 417 LYS A O   1 
ATOM   2929 C CB  . LYS A 1 436 ? 142.020 113.276 85.962  1.00 91.94  ? 417 LYS A CB  1 
ATOM   2930 C CG  . LYS A 1 436 ? 141.905 113.701 84.495  1.00 91.94  ? 417 LYS A CG  1 
ATOM   2931 C CD  . LYS A 1 436 ? 141.708 112.527 83.540  1.00 91.94  ? 417 LYS A CD  1 
ATOM   2932 C CE  . LYS A 1 436 ? 142.893 111.571 83.578  1.00 91.94  ? 417 LYS A CE  1 
ATOM   2933 N NZ  . LYS A 1 436 ? 143.000 110.764 82.333  1.00 91.94  ? 417 LYS A NZ  1 
ATOM   2934 N N   . ARG A 1 437 ? 139.807 112.251 88.606  1.00 87.13  ? 418 ARG A N   1 
ATOM   2935 C CA  . ARG A 1 437 ? 139.737 112.112 90.050  1.00 87.13  ? 418 ARG A CA  1 
ATOM   2936 C C   . ARG A 1 437 ? 140.319 110.768 90.481  1.00 87.13  ? 418 ARG A C   1 
ATOM   2937 O O   . ARG A 1 437 ? 140.317 109.804 89.710  1.00 87.13  ? 418 ARG A O   1 
ATOM   2938 C CB  . ARG A 1 437 ? 138.295 112.205 90.540  1.00 87.13  ? 418 ARG A CB  1 
ATOM   2939 C CG  . ARG A 1 437 ? 137.647 113.547 90.352  1.00 87.13  ? 418 ARG A CG  1 
ATOM   2940 C CD  . ARG A 1 437 ? 136.238 113.537 90.899  1.00 87.13  ? 418 ARG A CD  1 
ATOM   2941 N NE  . ARG A 1 437 ? 136.240 113.367 92.347  1.00 87.13  ? 418 ARG A NE  1 
ATOM   2942 C CZ  . ARG A 1 437 ? 136.329 114.371 93.211  1.00 87.13  ? 418 ARG A CZ  1 
ATOM   2943 N NH1 . ARG A 1 437 ? 136.417 115.618 92.774  1.00 87.13  ? 418 ARG A NH1 1 
ATOM   2944 N NH2 . ARG A 1 437 ? 136.327 114.130 94.513  1.00 87.13  ? 418 ARG A NH2 1 
ATOM   2945 N N   . PRO A 1 438 ? 140.820 110.673 91.705  1.00 88.23  ? 419 PRO A N   1 
ATOM   2946 C CA  . PRO A 1 438 ? 141.169 109.352 92.237  1.00 88.23  ? 419 PRO A CA  1 
ATOM   2947 C C   . PRO A 1 438 ? 139.913 108.563 92.562  1.00 88.23  ? 419 PRO A C   1 
ATOM   2948 O O   . PRO A 1 438 ? 139.256 108.807 93.578  1.00 88.23  ? 419 PRO A O   1 
ATOM   2949 C CB  . PRO A 1 438 ? 141.985 109.681 93.491  1.00 88.23  ? 419 PRO A CB  1 
ATOM   2950 C CG  . PRO A 1 438 ? 141.503 111.028 93.907  1.00 88.23  ? 419 PRO A CG  1 
ATOM   2951 C CD  . PRO A 1 438 ? 141.128 111.759 92.651  1.00 88.23  ? 419 PRO A CD  1 
ATOM   2952 N N   . ARG A 1 439 ? 139.572 107.610 91.698  1.00 86.18  ? 420 ARG A N   1 
ATOM   2953 C CA  . ARG A 1 439 ? 138.352 106.826 91.847  1.00 86.18  ? 420 ARG A CA  1 
ATOM   2954 C C   . ARG A 1 439 ? 138.720 105.399 92.221  1.00 86.18  ? 420 ARG A C   1 
ATOM   2955 O O   . ARG A 1 439 ? 139.090 104.604 91.344  1.00 86.18  ? 420 ARG A O   1 
ATOM   2956 C CB  . ARG A 1 439 ? 137.537 106.849 90.551  1.00 86.18  ? 420 ARG A CB  1 
ATOM   2957 C CG  . ARG A 1 439 ? 137.097 108.236 90.112  1.00 86.18  ? 420 ARG A CG  1 
ATOM   2958 C CD  . ARG A 1 439 ? 136.034 108.155 89.026  1.00 86.18  ? 420 ARG A CD  1 
ATOM   2959 N NE  . ARG A 1 439 ? 134.902 109.040 89.282  1.00 86.18  ? 420 ARG A NE  1 
ATOM   2960 C CZ  . ARG A 1 439 ? 134.892 110.342 89.015  1.00 86.18  ? 420 ARG A CZ  1 
ATOM   2961 N NH1 . ARG A 1 439 ? 135.956 110.920 88.477  1.00 86.18  ? 420 ARG A NH1 1 
ATOM   2962 N NH2 . ARG A 1 439 ? 133.816 111.066 89.282  1.00 86.18  ? 420 ARG A NH2 1 
ATOM   2963 N N   . PRO A 1 440 ? 138.646 105.021 93.499  1.00 79.71  ? 421 PRO A N   1 
ATOM   2964 C CA  . PRO A 1 440 ? 138.997 103.643 93.874  1.00 79.71  ? 421 PRO A CA  1 
ATOM   2965 C C   . PRO A 1 440 ? 138.086 102.601 93.261  1.00 79.71  ? 421 PRO A C   1 
ATOM   2966 O O   . PRO A 1 440 ? 138.397 101.407 93.340  1.00 79.71  ? 421 PRO A O   1 
ATOM   2967 C CB  . PRO A 1 440 ? 138.891 103.653 95.405  1.00 79.71  ? 421 PRO A CB  1 
ATOM   2968 C CG  . PRO A 1 440 ? 138.044 104.824 95.725  1.00 79.71  ? 421 PRO A CG  1 
ATOM   2969 C CD  . PRO A 1 440 ? 138.315 105.845 94.669  1.00 79.71  ? 421 PRO A CD  1 
ATOM   2970 N N   . LEU A 1 441 ? 136.976 103.011 92.654  1.00 73.12  ? 422 LEU A N   1 
ATOM   2971 C CA  . LEU A 1 441 ? 136.207 102.137 91.782  1.00 73.12  ? 422 LEU A CA  1 
ATOM   2972 C C   . LEU A 1 441 ? 135.321 103.009 90.909  1.00 73.12  ? 422 LEU A C   1 
ATOM   2973 O O   . LEU A 1 441 ? 134.682 103.940 91.403  1.00 73.12  ? 422 LEU A O   1 
ATOM   2974 C CB  . LEU A 1 441 ? 135.369 101.121 92.572  1.00 73.12  ? 422 LEU A CB  1 
ATOM   2975 C CG  . LEU A 1 441 ? 134.279 101.561 93.548  1.00 73.12  ? 422 LEU A CG  1 
ATOM   2976 C CD1 . LEU A 1 441 ? 132.942 101.744 92.860  1.00 73.12  ? 422 LEU A CD1 1 
ATOM   2977 C CD2 . LEU A 1 441 ? 134.161 100.533 94.648  1.00 73.12  ? 422 LEU A CD2 1 
ATOM   2978 N N   . LYS A 1 442 ? 135.303 102.714 89.613  1.00 74.70  ? 423 LYS A N   1 
ATOM   2979 C CA  . LYS A 1 442 ? 134.443 103.407 88.662  1.00 74.70  ? 423 LYS A CA  1 
ATOM   2980 C C   . LYS A 1 442 ? 133.570 102.373 87.965  1.00 74.70  ? 423 LYS A C   1 
ATOM   2981 O O   . LYS A 1 442 ? 134.034 101.652 87.075  1.00 74.70  ? 423 LYS A O   1 
ATOM   2982 C CB  . LYS A 1 442 ? 135.261 104.227 87.661  1.00 74.70  ? 423 LYS A CB  1 
ATOM   2983 C CG  . LYS A 1 442 ? 136.420 103.495 87.002  1.00 74.70  ? 423 LYS A CG  1 
ATOM   2984 C CD  . LYS A 1 442 ? 136.957 104.287 85.822  1.00 74.70  ? 423 LYS A CD  1 
ATOM   2985 C CE  . LYS A 1 442 ? 137.632 105.570 86.271  1.00 74.70  ? 423 LYS A CE  1 
ATOM   2986 N NZ  . LYS A 1 442 ? 138.205 106.326 85.123  1.00 74.70  ? 423 LYS A NZ  1 
ATOM   2987 N N   . LEU A 1 443 ? 132.314 102.286 88.385  1.00 73.78  ? 424 LEU A N   1 
ATOM   2988 C CA  . LEU A 1 443 ? 131.371 101.412 87.715  1.00 73.78  ? 424 LEU A CA  1 
ATOM   2989 C C   . LEU A 1 443 ? 130.985 102.004 86.366  1.00 73.78  ? 424 LEU A C   1 
ATOM   2990 O O   . LEU A 1 443 ? 131.120 103.207 86.126  1.00 73.78  ? 424 LEU A O   1 
ATOM   2991 C CB  . LEU A 1 443 ? 130.131 101.198 88.580  1.00 73.78  ? 424 LEU A CB  1 
ATOM   2992 C CG  . LEU A 1 443 ? 130.400 100.539 89.932  1.00 73.78  ? 424 LEU A CG  1 
ATOM   2993 C CD1 . LEU A 1 443 ? 129.153 100.557 90.787  1.00 73.78  ? 424 LEU A CD1 1 
ATOM   2994 C CD2 . LEU A 1 443 ? 130.902 99.117  89.747  1.00 73.78  ? 424 LEU A CD2 1 
ATOM   2995 N N   . SER A 1 444 ? 130.516 101.136 85.474  1.00 80.10  ? 425 SER A N   1 
ATOM   2996 C CA  . SER A 1 444 ? 130.118 101.570 84.143  1.00 80.10  ? 425 SER A CA  1 
ATOM   2997 C C   . SER A 1 444 ? 129.050 102.654 84.223  1.00 80.10  ? 425 SER A C   1 
ATOM   2998 O O   . SER A 1 444 ? 128.114 102.570 85.022  1.00 80.10  ? 425 SER A O   1 
ATOM   2999 C CB  . SER A 1 444 ? 129.601 100.382 83.334  1.00 80.10  ? 425 SER A CB  1 
ATOM   3000 O OG  . SER A 1 444 ? 128.779 100.816 82.267  1.00 80.10  ? 425 SER A OG  1 
ATOM   3001 N N   . VAL A 1 445 ? 129.202 103.684 83.386  1.00 77.24  ? 426 VAL A N   1 
ATOM   3002 C CA  . VAL A 1 445 ? 128.251 104.786 83.313  1.00 77.24  ? 426 VAL A CA  1 
ATOM   3003 C C   . VAL A 1 445 ? 126.825 104.306 83.061  1.00 77.24  ? 426 VAL A C   1 
ATOM   3004 O O   . VAL A 1 445 ? 125.868 105.055 83.297  1.00 77.24  ? 426 VAL A O   1 
ATOM   3005 C CB  . VAL A 1 445 ? 128.721 105.779 82.223  1.00 77.24  ? 426 VAL A CB  1 
ATOM   3006 C CG1 . VAL A 1 445 ? 128.815 105.086 80.873  1.00 77.24  ? 426 VAL A CG1 1 
ATOM   3007 C CG2 . VAL A 1 445 ? 127.832 107.016 82.161  1.00 77.24  ? 426 VAL A CG2 1 
ATOM   3008 N N   . PHE A 1 446 ? 126.668 103.067 82.588  1.00 75.73  ? 427 PHE A N   1 
ATOM   3009 C CA  . PHE A 1 446 ? 125.352 102.444 82.485  1.00 75.73  ? 427 PHE A CA  1 
ATOM   3010 C C   . PHE A 1 446 ? 124.565 102.585 83.784  1.00 75.73  ? 427 PHE A C   1 
ATOM   3011 O O   . PHE A 1 446 ? 123.381 102.944 83.769  1.00 75.73  ? 427 PHE A O   1 
ATOM   3012 C CB  . PHE A 1 446 ? 125.522 100.973 82.103  1.00 75.73  ? 427 PHE A CB  1 
ATOM   3013 C CG  . PHE A 1 446 ? 124.317 100.120 82.378  1.00 75.73  ? 427 PHE A CG  1 
ATOM   3014 C CD1 . PHE A 1 446 ? 123.225 100.140 81.530  1.00 75.73  ? 427 PHE A CD1 1 
ATOM   3015 C CD2 . PHE A 1 446 ? 124.288 99.277  83.476  1.00 75.73  ? 427 PHE A CD2 1 
ATOM   3016 C CE1 . PHE A 1 446 ? 122.125 99.344  81.779  1.00 75.73  ? 427 PHE A CE1 1 
ATOM   3017 C CE2 . PHE A 1 446 ? 123.190 98.483  83.730  1.00 75.73  ? 427 PHE A CE2 1 
ATOM   3018 C CZ  . PHE A 1 446 ? 122.108 98.517  82.882  1.00 75.73  ? 427 PHE A CZ  1 
ATOM   3019 N N   . PHE A 1 447 ? 125.210 102.322 84.922  1.00 73.11  ? 428 PHE A N   1 
ATOM   3020 C CA  . PHE A 1 447 ? 124.500 102.390 86.198  1.00 73.11  ? 428 PHE A CA  1 
ATOM   3021 C C   . PHE A 1 447 ? 124.017 103.799 86.517  1.00 73.11  ? 428 PHE A C   1 
ATOM   3022 O O   . PHE A 1 447 ? 122.813 103.968 86.783  1.00 73.11  ? 428 PHE A O   1 
ATOM   3023 C CB  . PHE A 1 447 ? 125.382 101.834 87.321  1.00 73.11  ? 428 PHE A CB  1 
ATOM   3024 C CG  . PHE A 1 447 ? 125.675 100.373 87.199  1.00 73.11  ? 428 PHE A CG  1 
ATOM   3025 C CD1 . PHE A 1 447 ? 126.609 99.913  86.293  1.00 73.11  ? 428 PHE A CD1 1 
ATOM   3026 C CD2 . PHE A 1 447 ? 125.036 99.459  88.012  1.00 73.11  ? 428 PHE A CD2 1 
ATOM   3027 C CE1 . PHE A 1 447 ? 126.887 98.566  86.186  1.00 73.11  ? 428 PHE A CE1 1 
ATOM   3028 C CE2 . PHE A 1 447 ? 125.311 98.110  87.910  1.00 73.11  ? 428 PHE A CE2 1 
ATOM   3029 C CZ  . PHE A 1 447 ? 126.237 97.664  86.997  1.00 73.11  ? 428 PHE A CZ  1 
ATOM   3030 N N   . PRO A 1 448 ? 124.862 104.838 86.512  1.00 69.09  ? 429 PRO A N   1 
ATOM   3031 C CA  . PRO A 1 448 ? 124.328 106.181 86.772  1.00 69.09  ? 429 PRO A CA  1 
ATOM   3032 C C   . PRO A 1 448 ? 123.305 106.629 85.752  1.00 69.09  ? 429 PRO A C   1 
ATOM   3033 O O   . PRO A 1 448 ? 122.340 107.295 86.131  1.00 69.09  ? 429 PRO A O   1 
ATOM   3034 C CB  . PRO A 1 448 ? 125.578 107.071 86.750  1.00 69.09  ? 429 PRO A CB  1 
ATOM   3035 C CG  . PRO A 1 448 ? 126.697 106.161 87.013  1.00 69.09  ? 429 PRO A CG  1 
ATOM   3036 C CD  . PRO A 1 448 ? 126.328 104.867 86.379  1.00 69.09  ? 429 PRO A CD  1 
ATOM   3037 N N   . ILE A 1 449 ? 123.456 106.274 84.473  1.00 72.04  ? 430 ILE A N   1 
ATOM   3038 C CA  . ILE A 1 449 ? 122.504 106.787 83.491  1.00 72.04  ? 430 ILE A CA  1 
ATOM   3039 C C   . ILE A 1 449 ? 121.139 106.125 83.663  1.00 72.04  ? 430 ILE A C   1 
ATOM   3040 O O   . ILE A 1 449 ? 120.098 106.799 83.609  1.00 72.04  ? 430 ILE A O   1 
ATOM   3041 C CB  . ILE A 1 449 ? 123.048 106.642 82.055  1.00 72.04  ? 430 ILE A CB  1 
ATOM   3042 C CG1 . ILE A 1 449 ? 122.142 107.385 81.073  1.00 72.04  ? 430 ILE A CG1 1 
ATOM   3043 C CG2 . ILE A 1 449 ? 123.170 105.193 81.639  1.00 72.04  ? 430 ILE A CG2 1 
ATOM   3044 C CD1 . ILE A 1 449 ? 121.926 108.837 81.422  1.00 72.04  ? 430 ILE A CD1 1 
ATOM   3045 N N   . VAL A 1 450 ? 121.107 104.813 83.913  1.00 68.58  ? 431 VAL A N   1 
ATOM   3046 C CA  . VAL A 1 450 ? 119.802 104.181 84.066  1.00 68.58  ? 431 VAL A CA  1 
ATOM   3047 C C   . VAL A 1 450 ? 119.179 104.557 85.400  1.00 68.58  ? 431 VAL A C   1 
ATOM   3048 O O   . VAL A 1 450 ? 117.952 104.691 85.497  1.00 68.58  ? 431 VAL A O   1 
ATOM   3049 C CB  . VAL A 1 450 ? 119.885 102.655 83.881  1.00 68.58  ? 431 VAL A CB  1 
ATOM   3050 C CG1 . VAL A 1 450 ? 120.544 102.326 82.557  1.00 68.58  ? 431 VAL A CG1 1 
ATOM   3051 C CG2 . VAL A 1 450 ? 120.616 102.004 85.030  1.00 68.58  ? 431 VAL A CG2 1 
ATOM   3052 N N   . PHE A 1 451 ? 119.984 104.795 86.438  1.00 64.61  ? 432 PHE A N   1 
ATOM   3053 C CA  . PHE A 1 451 ? 119.353 105.255 87.666  1.00 64.61  ? 432 PHE A CA  1 
ATOM   3054 C C   . PHE A 1 451 ? 118.914 106.708 87.565  1.00 64.61  ? 432 PHE A C   1 
ATOM   3055 O O   . PHE A 1 451 ? 117.954 107.103 88.228  1.00 64.61  ? 432 PHE A O   1 
ATOM   3056 C CB  . PHE A 1 451 ? 120.272 105.069 88.867  1.00 64.61  ? 432 PHE A CB  1 
ATOM   3057 C CG  . PHE A 1 451 ? 119.571 105.261 90.175  1.00 64.61  ? 432 PHE A CG  1 
ATOM   3058 C CD1 . PHE A 1 451 ? 118.378 104.609 90.427  1.00 64.61  ? 432 PHE A CD1 1 
ATOM   3059 C CD2 . PHE A 1 451 ? 120.078 106.111 91.137  1.00 64.61  ? 432 PHE A CD2 1 
ATOM   3060 C CE1 . PHE A 1 451 ? 117.713 104.784 91.617  1.00 64.61  ? 432 PHE A CE1 1 
ATOM   3061 C CE2 . PHE A 1 451 ? 119.416 106.287 92.330  1.00 64.61  ? 432 PHE A CE2 1 
ATOM   3062 C CZ  . PHE A 1 451 ? 118.230 105.623 92.568  1.00 64.61  ? 432 PHE A CZ  1 
ATOM   3063 N N   . CYS A 1 452 ? 119.570 107.510 86.725  1.00 69.54  ? 433 CYS A N   1 
ATOM   3064 C CA  . CYS A 1 452 ? 119.088 108.863 86.483  1.00 69.54  ? 433 CYS A CA  1 
ATOM   3065 C C   . CYS A 1 452 ? 117.757 108.840 85.751  1.00 69.54  ? 433 CYS A C   1 
ATOM   3066 O O   . CYS A 1 452 ? 116.860 109.631 86.059  1.00 69.54  ? 433 CYS A O   1 
ATOM   3067 C CB  . CYS A 1 452 ? 120.118 109.660 85.688  1.00 69.54  ? 433 CYS A CB  1 
ATOM   3068 S SG  . CYS A 1 452 ? 119.521 111.262 85.114  1.00 69.54  ? 433 CYS A SG  1 
ATOM   3069 N N   . ILE A 1 453 ? 117.604 107.937 84.782  1.00 67.12  ? 434 ILE A N   1 
ATOM   3070 C CA  . ILE A 1 453 ? 116.311 107.807 84.113  1.00 67.12  ? 434 ILE A CA  1 
ATOM   3071 C C   . ILE A 1 453 ? 115.246 107.329 85.095  1.00 67.12  ? 434 ILE A C   1 
ATOM   3072 O O   . ILE A 1 453 ? 114.108 107.822 85.095  1.00 67.12  ? 434 ILE A O   1 
ATOM   3073 C CB  . ILE A 1 453 ? 116.430 106.876 82.894  1.00 67.12  ? 434 ILE A CB  1 
ATOM   3074 C CG1 . ILE A 1 453 ? 117.325 107.517 81.834  1.00 67.12  ? 434 ILE A CG1 1 
ATOM   3075 C CG2 . ILE A 1 453 ? 115.063 106.571 82.319  1.00 67.12  ? 434 ILE A CG2 1 
ATOM   3076 C CD1 . ILE A 1 453 ? 117.683 106.596 80.702  1.00 67.12  ? 434 ILE A CD1 1 
ATOM   3077 N N   . CYS A 1 454 ? 115.600 106.375 85.959  1.00 64.34  ? 435 CYS A N   1 
ATOM   3078 C CA  . CYS A 1 454 ? 114.649 105.911 86.964  1.00 64.34  ? 435 CYS A CA  1 
ATOM   3079 C C   . CYS A 1 454 ? 114.253 107.036 87.911  1.00 64.34  ? 435 CYS A C   1 
ATOM   3080 O O   . CYS A 1 454 ? 113.089 107.140 88.313  1.00 64.34  ? 435 CYS A O   1 
ATOM   3081 C CB  . CYS A 1 454 ? 115.233 104.737 87.744  1.00 64.34  ? 435 CYS A CB  1 
ATOM   3082 S SG  . CYS A 1 454 ? 114.186 104.165 89.100  1.00 64.34  ? 435 CYS A SG  1 
ATOM   3083 N N   . SER A 1 455 ? 115.203 107.896 88.277  1.00 65.39  ? 436 SER A N   1 
ATOM   3084 C CA  . SER A 1 455 ? 114.867 109.005 89.161  1.00 65.39  ? 436 SER A CA  1 
ATOM   3085 C C   . SER A 1 455 ? 114.065 110.077 88.439  1.00 65.39  ? 436 SER A C   1 
ATOM   3086 O O   . SER A 1 455 ? 113.272 110.779 89.070  1.00 65.39  ? 436 SER A O   1 
ATOM   3087 C CB  . SER A 1 455 ? 116.125 109.616 89.760  1.00 65.39  ? 436 SER A CB  1 
ATOM   3088 O OG  . SER A 1 455 ? 115.850 110.935 90.186  1.00 65.39  ? 436 SER A OG  1 
ATOM   3089 N N   . VAL A 1 456 ? 114.241 110.215 87.124  1.00 65.90  ? 437 VAL A N   1 
ATOM   3090 C CA  . VAL A 1 456 ? 113.367 111.104 86.365  1.00 65.90  ? 437 VAL A CA  1 
ATOM   3091 C C   . VAL A 1 456 ? 111.940 110.579 86.405  1.00 65.90  ? 437 VAL A C   1 
ATOM   3092 O O   . VAL A 1 456 ? 110.982 111.340 86.589  1.00 65.90  ? 437 VAL A O   1 
ATOM   3093 C CB  . VAL A 1 456 ? 113.876 111.264 84.922  1.00 65.90  ? 437 VAL A CB  1 
ATOM   3094 C CG1 . VAL A 1 456 ? 112.797 111.867 84.046  1.00 65.90  ? 437 VAL A CG1 1 
ATOM   3095 C CG2 . VAL A 1 456 ? 115.117 112.133 84.895  1.00 65.90  ? 437 VAL A CG2 1 
ATOM   3096 N N   . PHE A 1 457 ? 111.780 109.264 86.257  1.00 65.94  ? 438 PHE A N   1 
ATOM   3097 C CA  . PHE A 1 457 ? 110.476 108.642 86.476  1.00 65.94  ? 438 PHE A CA  1 
ATOM   3098 C C   . PHE A 1 457 ? 109.929 108.967 87.864  1.00 65.94  ? 438 PHE A C   1 
ATOM   3099 O O   . PHE A 1 457 ? 108.774 109.389 88.014  1.00 65.94  ? 438 PHE A O   1 
ATOM   3100 C CB  . PHE A 1 457 ? 110.587 107.128 86.289  1.00 65.94  ? 438 PHE A CB  1 
ATOM   3101 C CG  . PHE A 1 457 ? 109.325 106.384 86.608  1.00 65.94  ? 438 PHE A CG  1 
ATOM   3102 C CD1 . PHE A 1 457 ? 108.261 106.390 85.730  1.00 65.94  ? 438 PHE A CD1 1 
ATOM   3103 C CD2 . PHE A 1 457 ? 109.206 105.679 87.789  1.00 65.94  ? 438 PHE A CD2 1 
ATOM   3104 C CE1 . PHE A 1 457 ? 107.100 105.706 86.025  1.00 65.94  ? 438 PHE A CE1 1 
ATOM   3105 C CE2 . PHE A 1 457 ? 108.050 104.996 88.089  1.00 65.94  ? 438 PHE A CE2 1 
ATOM   3106 C CZ  . PHE A 1 457 ? 106.997 105.009 87.207  1.00 65.94  ? 438 PHE A CZ  1 
ATOM   3107 N N   . LEU A 1 458 ? 110.753 108.757 88.893  1.00 65.23  ? 439 LEU A N   1 
ATOM   3108 C CA  . LEU A 1 458 ? 110.316 108.901 90.278  1.00 65.23  ? 439 LEU A CA  1 
ATOM   3109 C C   . LEU A 1 458 ? 110.048 110.343 90.679  1.00 65.23  ? 439 LEU A C   1 
ATOM   3110 O O   . LEU A 1 458 ? 109.401 110.568 91.703  1.00 65.23  ? 439 LEU A O   1 
ATOM   3111 C CB  . LEU A 1 458 ? 111.353 108.298 91.222  1.00 65.23  ? 439 LEU A CB  1 
ATOM   3112 C CG  . LEU A 1 458 ? 111.465 106.780 91.198  1.00 65.23  ? 439 LEU A CG  1 
ATOM   3113 C CD1 . LEU A 1 458 ? 112.669 106.329 91.980  1.00 65.23  ? 439 LEU A CD1 1 
ATOM   3114 C CD2 . LEU A 1 458 ? 110.218 106.189 91.795  1.00 65.23  ? 439 LEU A CD2 1 
ATOM   3115 N N   . VAL A 1 459 ? 110.578 111.321 89.943  1.00 64.49  ? 440 VAL A N   1 
ATOM   3116 C CA  . VAL A 1 459 ? 110.267 112.719 90.224  1.00 64.49  ? 440 VAL A CA  1 
ATOM   3117 C C   . VAL A 1 459 ? 109.236 113.295 89.271  1.00 64.49  ? 440 VAL A C   1 
ATOM   3118 O O   . VAL A 1 459 ? 108.745 114.409 89.513  1.00 64.49  ? 440 VAL A O   1 
ATOM   3119 C CB  . VAL A 1 459 ? 111.528 113.606 90.201  1.00 64.49  ? 440 VAL A CB  1 
ATOM   3120 C CG1 . VAL A 1 459 ? 112.592 113.022 91.099  1.00 64.49  ? 440 VAL A CG1 1 
ATOM   3121 C CG2 . VAL A 1 459 ? 112.038 113.767 88.788  1.00 64.49  ? 440 VAL A CG2 1 
ATOM   3122 N N   . ILE A 1 460 ? 108.893 112.589 88.197  1.00 68.79  ? 441 ILE A N   1 
ATOM   3123 C CA  . ILE A 1 460 ? 107.786 113.036 87.363  1.00 68.79  ? 441 ILE A CA  1 
ATOM   3124 C C   . ILE A 1 460 ? 106.461 112.448 87.838  1.00 68.79  ? 441 ILE A C   1 
ATOM   3125 O O   . ILE A 1 460 ? 105.425 113.114 87.746  1.00 68.79  ? 441 ILE A O   1 
ATOM   3126 C CB  . ILE A 1 460 ? 108.052 112.703 85.885  1.00 68.79  ? 441 ILE A CB  1 
ATOM   3127 C CG1 . ILE A 1 460 ? 109.165 113.595 85.331  1.00 68.79  ? 441 ILE A CG1 1 
ATOM   3128 C CG2 . ILE A 1 460 ? 106.793 112.882 85.048  1.00 68.79  ? 441 ILE A CG2 1 
ATOM   3129 C CD1 . ILE A 1 460 ? 108.770 115.049 85.192  1.00 68.79  ? 441 ILE A CD1 1 
ATOM   3130 N N   . VAL A 1 461 ? 106.469 111.223 88.370  1.00 70.51  ? 442 VAL A N   1 
ATOM   3131 C CA  . VAL A 1 461 ? 105.230 110.641 88.896  1.00 70.51  ? 442 VAL A CA  1 
ATOM   3132 C C   . VAL A 1 461 ? 104.590 111.520 89.967  1.00 70.51  ? 442 VAL A C   1 
ATOM   3133 O O   . VAL A 1 461 ? 103.369 111.734 89.907  1.00 70.51  ? 442 VAL A O   1 
ATOM   3134 C CB  . VAL A 1 461 ? 105.482 109.200 89.375  1.00 70.51  ? 442 VAL A CB  1 
ATOM   3135 C CG1 . VAL A 1 461 ? 104.323 108.713 90.221  1.00 70.51  ? 442 VAL A CG1 1 
ATOM   3136 C CG2 . VAL A 1 461 ? 105.692 108.281 88.187  1.00 70.51  ? 442 VAL A CG2 1 
ATOM   3137 N N   . PRO A 1 462 ? 105.327 112.068 90.951  1.00 71.61  ? 443 PRO A N   1 
ATOM   3138 C CA  . PRO A 1 462 ? 104.690 112.980 91.908  1.00 71.61  ? 443 PRO A CA  1 
ATOM   3139 C C   . PRO A 1 462 ? 104.563 114.397 91.379  1.00 71.61  ? 443 PRO A C   1 
ATOM   3140 O O   . PRO A 1 462 ? 104.277 115.324 92.141  1.00 71.61  ? 443 PRO A O   1 
ATOM   3141 C CB  . PRO A 1 462 ? 105.632 112.931 93.119  1.00 71.61  ? 443 PRO A CB  1 
ATOM   3142 C CG  . PRO A 1 462 ? 106.408 111.686 92.942  1.00 71.61  ? 443 PRO A CG  1 
ATOM   3143 C CD  . PRO A 1 462 ? 106.627 111.625 91.469  1.00 71.61  ? 443 PRO A CD  1 
ATOM   3144 N N   . LEU A 1 463 ? 104.787 114.583 90.081  1.00 71.99  ? 444 LEU A N   1 
ATOM   3145 C CA  . LEU A 1 463 ? 104.477 115.850 89.435  1.00 71.99  ? 444 LEU A CA  1 
ATOM   3146 C C   . LEU A 1 463 ? 103.231 115.778 88.568  1.00 71.99  ? 444 LEU A C   1 
ATOM   3147 O O   . LEU A 1 463 ? 102.588 116.808 88.341  1.00 71.99  ? 444 LEU A O   1 
ATOM   3148 C CB  . LEU A 1 463 ? 105.659 116.327 88.588  1.00 71.99  ? 444 LEU A CB  1 
ATOM   3149 C CG  . LEU A 1 463 ? 106.668 117.195 89.334  1.00 71.99  ? 444 LEU A CG  1 
ATOM   3150 C CD1 . LEU A 1 463 ? 107.593 117.893 88.356  1.00 71.99  ? 444 LEU A CD1 1 
ATOM   3151 C CD2 . LEU A 1 463 ? 105.944 118.205 90.198  1.00 71.99  ? 444 LEU A CD2 1 
ATOM   3152 N N   . PHE A 1 464 ? 102.875 114.590 88.079  1.00 79.85  ? 445 PHE A N   1 
ATOM   3153 C CA  . PHE A 1 464 ? 101.593 114.420 87.408  1.00 79.85  ? 445 PHE A CA  1 
ATOM   3154 C C   . PHE A 1 464 ? 100.458 114.447 88.424  1.00 79.85  ? 445 PHE A C   1 
ATOM   3155 O O   . PHE A 1 464 ? 99.612  115.347 88.404  1.00 79.85  ? 445 PHE A O   1 
ATOM   3156 C CB  . PHE A 1 464 ? 101.587 113.112 86.613  1.00 79.85  ? 445 PHE A CB  1 
ATOM   3157 C CG  . PHE A 1 464 ? 100.227 112.700 86.129  1.00 79.85  ? 445 PHE A CG  1 
ATOM   3158 C CD1 . PHE A 1 464 ? 99.468  113.550 85.342  1.00 79.85  ? 445 PHE A CD1 1 
ATOM   3159 C CD2 . PHE A 1 464 ? 99.709  111.459 86.458  1.00 79.85  ? 445 PHE A CD2 1 
ATOM   3160 C CE1 . PHE A 1 464 ? 98.216  113.172 84.895  1.00 79.85  ? 445 PHE A CE1 1 
ATOM   3161 C CE2 . PHE A 1 464 ? 98.458  111.076 86.014  1.00 79.85  ? 445 PHE A CE2 1 
ATOM   3162 C CZ  . PHE A 1 464 ? 97.710  111.934 85.231  1.00 79.85  ? 445 PHE A CZ  1 
ATOM   3163 N N   . THR A 1 465 ? 100.432 113.475 89.328  1.00 81.13  ? 446 THR A N   1 
ATOM   3164 C CA  . THR A 1 465 ? 99.575  113.558 90.498  1.00 81.13  ? 446 THR A CA  1 
ATOM   3165 C C   . THR A 1 465 ? 100.270 114.377 91.578  1.00 81.13  ? 446 THR A C   1 
ATOM   3166 O O   . THR A 1 465 ? 101.433 114.760 91.440  1.00 81.13  ? 446 THR A O   1 
ATOM   3167 C CB  . THR A 1 465 ? 99.233  112.167 91.030  1.00 81.13  ? 446 THR A CB  1 
ATOM   3168 O OG1 . THR A 1 465 ? 98.504  112.291 92.257  1.00 81.13  ? 446 THR A OG1 1 
ATOM   3169 C CG2 . THR A 1 465 ? 100.497 111.369 91.281  1.00 81.13  ? 446 THR A CG2 1 
ATOM   3170 N N   . ASP A 1 466 ? 99.544  114.623 92.671  1.00 83.44  ? 447 ASP A N   1 
ATOM   3171 C CA  . ASP A 1 466 ? 100.062 115.384 93.811  1.00 83.44  ? 447 ASP A CA  1 
ATOM   3172 C C   . ASP A 1 466 ? 100.831 116.620 93.355  1.00 83.44  ? 447 ASP A C   1 
ATOM   3173 O O   . ASP A 1 466 ? 101.913 116.925 93.858  1.00 83.44  ? 447 ASP A O   1 
ATOM   3174 C CB  . ASP A 1 466 ? 100.937 114.505 94.705  1.00 83.44  ? 447 ASP A CB  1 
ATOM   3175 C CG  . ASP A 1 466 ? 100.126 113.649 95.654  1.00 83.44  ? 447 ASP A CG  1 
ATOM   3176 O OD1 . ASP A 1 466 ? 99.010  114.067 96.026  1.00 83.44  ? 447 ASP A OD1 1 
ATOM   3177 O OD2 . ASP A 1 466 ? 100.603 112.557 96.025  1.00 83.44  ? 447 ASP A OD2 1 
ATOM   3178 N N   . THR A 1 467 ? 100.274 117.332 92.376  1.00 77.69  ? 448 THR A N   1 
ATOM   3179 C CA  . THR A 1 467 ? 101.002 118.449 91.787  1.00 77.69  ? 448 THR A CA  1 
ATOM   3180 C C   . THR A 1 467 ? 100.991 119.663 92.705  1.00 77.69  ? 448 THR A C   1 
ATOM   3181 O O   . THR A 1 467 ? 102.029 120.303 92.905  1.00 77.69  ? 448 THR A O   1 
ATOM   3182 C CB  . THR A 1 467 ? 100.413 118.802 90.424  1.00 77.69  ? 448 THR A CB  1 
ATOM   3183 O OG1 . THR A 1 467 ? 100.466 117.652 89.571  1.00 77.69  ? 448 THR A OG1 1 
ATOM   3184 C CG2 . THR A 1 467 ? 101.202 119.933 89.785  1.00 77.69  ? 448 THR A CG2 1 
ATOM   3185 N N   . ILE A 1 468 ? 99.835  119.991 93.282  1.00 75.01  ? 449 ILE A N   1 
ATOM   3186 C CA  . ILE A 1 468 ? 99.774  121.111 94.216  1.00 75.01  ? 449 ILE A CA  1 
ATOM   3187 C C   . ILE A 1 468 ? 100.633 120.830 95.442  1.00 75.01  ? 449 ILE A C   1 
ATOM   3188 O O   . ILE A 1 468 ? 101.362 121.705 95.924  1.00 75.01  ? 449 ILE A O   1 
ATOM   3189 C CB  . ILE A 1 468 ? 98.312  121.407 94.596  1.00 75.01  ? 449 ILE A CB  1 
ATOM   3190 C CG1 . ILE A 1 468 ? 97.569  120.103 94.893  1.00 75.01  ? 449 ILE A CG1 1 
ATOM   3191 C CG2 . ILE A 1 468 ? 97.629  122.184 93.485  1.00 75.01  ? 449 ILE A CG2 1 
ATOM   3192 C CD1 . ILE A 1 468 ? 96.097  120.282 95.178  1.00 75.01  ? 449 ILE A CD1 1 
ATOM   3193 N N   . ASN A 1 469 ? 100.573 119.601 95.956  1.00 75.26  ? 450 ASN A N   1 
ATOM   3194 C CA  . ASN A 1 469 ? 101.389 119.234 97.108  1.00 75.26  ? 450 ASN A CA  1 
ATOM   3195 C C   . ASN A 1 469 ? 102.874 119.347 96.790  1.00 75.26  ? 450 ASN A C   1 
ATOM   3196 O O   . ASN A 1 469 ? 103.632 119.982 97.530  1.00 75.26  ? 450 ASN A O   1 
ATOM   3197 C CB  . ASN A 1 469 ? 101.037 117.823 97.568  1.00 75.26  ? 450 ASN A CB  1 
ATOM   3198 C CG  . ASN A 1 469 ? 99.957  117.815 98.620  1.00 75.26  ? 450 ASN A CG  1 
ATOM   3199 O OD1 . ASN A 1 469 ? 99.681  118.836 99.246  1.00 75.26  ? 450 ASN A OD1 1 
ATOM   3200 N ND2 . ASN A 1 469 ? 99.333  116.662 98.820  1.00 75.26  ? 450 ASN A ND2 1 
ATOM   3201 N N   . SER A 1 470 ? 103.317 118.707 95.706  1.00 72.41  ? 451 SER A N   1 
ATOM   3202 C CA  . SER A 1 470 ? 104.731 118.758 95.348  1.00 72.41  ? 451 SER A CA  1 
ATOM   3203 C C   . SER A 1 470 ? 105.194 120.180 95.057  1.00 72.41  ? 451 SER A C   1 
ATOM   3204 O O   . SER A 1 470 ? 106.354 120.516 95.310  1.00 72.41  ? 451 SER A O   1 
ATOM   3205 C CB  . SER A 1 470 ? 104.997 117.857 94.147  1.00 72.41  ? 451 SER A CB  1 
ATOM   3206 O OG  . SER A 1 470 ? 104.717 116.506 94.463  1.00 72.41  ? 451 SER A OG  1 
ATOM   3207 N N   . LEU A 1 471 ? 104.312 121.036 94.541  1.00 71.82  ? 452 LEU A N   1 
ATOM   3208 C CA  . LEU A 1 471 ? 104.716 122.421 94.321  1.00 71.82  ? 452 LEU A CA  1 
ATOM   3209 C C   . LEU A 1 471 ? 104.788 123.200 95.627  1.00 71.82  ? 452 LEU A C   1 
ATOM   3210 O O   . LEU A 1 471 ? 105.626 124.097 95.764  1.00 71.82  ? 452 LEU A O   1 
ATOM   3211 C CB  . LEU A 1 471 ? 103.781 123.105 93.327  1.00 71.82  ? 452 LEU A CB  1 
ATOM   3212 C CG  . LEU A 1 471 ? 104.234 123.040 91.865  1.00 71.82  ? 452 LEU A CG  1 
ATOM   3213 C CD1 . LEU A 1 471 ? 105.527 123.814 91.699  1.00 71.82  ? 452 LEU A CD1 1 
ATOM   3214 C CD2 . LEU A 1 471 ? 104.420 121.616 91.376  1.00 71.82  ? 452 LEU A CD2 1 
ATOM   3215 N N   . ILE A 1 472 ? 103.949 122.866 96.609  1.00 70.37  ? 453 ILE A N   1 
ATOM   3216 C CA  . ILE A 1 472 ? 104.160 123.446 97.931  1.00 70.37  ? 453 ILE A CA  1 
ATOM   3217 C C   . ILE A 1 472 ? 105.463 122.925 98.526  1.00 70.37  ? 453 ILE A C   1 
ATOM   3218 O O   . ILE A 1 472 ? 106.138 123.630 99.285  1.00 70.37  ? 453 ILE A O   1 
ATOM   3219 C CB  . ILE A 1 472 ? 102.956 123.164 98.845  1.00 70.37  ? 453 ILE A CB  1 
ATOM   3220 C CG1 . ILE A 1 472 ? 101.689 123.777 98.253  1.00 70.37  ? 453 ILE A CG1 1 
ATOM   3221 C CG2 . ILE A 1 472 ? 103.191 123.731 100.230 1.00 70.37  ? 453 ILE A CG2 1 
ATOM   3222 C CD1 . ILE A 1 472 ? 100.499 123.735 99.184  1.00 70.37  ? 453 ILE A CD1 1 
ATOM   3223 N N   . GLY A 1 473 ? 105.857 121.704 98.168  1.00 66.74  ? 454 GLY A N   1 
ATOM   3224 C CA  . GLY A 1 473 ? 107.153 121.200 98.596  1.00 66.74  ? 454 GLY A CA  1 
ATOM   3225 C C   . GLY A 1 473 ? 108.301 121.955 97.953  1.00 66.74  ? 454 GLY A C   1 
ATOM   3226 O O   . GLY A 1 473 ? 109.326 122.214 98.592  1.00 66.74  ? 454 GLY A O   1 
ATOM   3227 N N   . ILE A 1 474 ? 108.144 122.314 96.679  1.00 65.32  ? 455 ILE A N   1 
ATOM   3228 C CA  . ILE A 1 474 ? 109.123 123.178 96.024  1.00 65.32  ? 455 ILE A CA  1 
ATOM   3229 C C   . ILE A 1 474 ? 109.170 124.534 96.710  1.00 65.32  ? 455 ILE A C   1 
ATOM   3230 O O   . ILE A 1 474 ? 110.242 125.117 96.886  1.00 65.32  ? 455 ILE A O   1 
ATOM   3231 C CB  . ILE A 1 474 ? 108.804 123.326 94.525  1.00 65.32  ? 455 ILE A CB  1 
ATOM   3232 C CG1 . ILE A 1 474 ? 109.200 122.073 93.756  1.00 65.32  ? 455 ILE A CG1 1 
ATOM   3233 C CG2 . ILE A 1 474 ? 109.513 124.533 93.938  1.00 65.32  ? 455 ILE A CG2 1 
ATOM   3234 C CD1 . ILE A 1 474 ? 108.836 122.145 92.293  1.00 65.32  ? 455 ILE A CD1 1 
ATOM   3235 N N   . GLY A 1 475 ? 108.009 125.062 97.098  1.00 64.60  ? 456 GLY A N   1 
ATOM   3236 C CA  . GLY A 1 475 ? 107.988 126.301 97.861  1.00 64.60  ? 456 GLY A CA  1 
ATOM   3237 C C   . GLY A 1 475 ? 108.747 126.189 99.169  1.00 64.60  ? 456 GLY A C   1 
ATOM   3238 O O   . GLY A 1 475 ? 109.500 127.091 99.544  1.00 64.60  ? 456 GLY A O   1 
ATOM   3239 N N   . ILE A 1 476 ? 108.567 125.071 99.875  1.00 61.06  ? 457 ILE A N   1 
ATOM   3240 C CA  . ILE A 1 476 ? 109.288 124.842 101.126 1.00 61.06  ? 457 ILE A CA  1 
ATOM   3241 C C   . ILE A 1 476 ? 110.791 124.826 100.879 1.00 61.06  ? 457 ILE A C   1 
ATOM   3242 O O   . ILE A 1 476 ? 111.555 125.537 101.542 1.00 61.06  ? 457 ILE A O   1 
ATOM   3243 C CB  . ILE A 1 476 ? 108.817 123.535 101.787 1.00 61.06  ? 457 ILE A CB  1 
ATOM   3244 C CG1 . ILE A 1 476 ? 107.517 123.764 102.553 1.00 61.06  ? 457 ILE A CG1 1 
ATOM   3245 C CG2 . ILE A 1 476 ? 109.885 122.991 102.714 1.00 61.06  ? 457 ILE A CG2 1 
ATOM   3246 C CD1 . ILE A 1 476 ? 106.898 122.495 103.078 1.00 61.06  ? 457 ILE A CD1 1 
ATOM   3247 N N   . ALA A 1 477 ? 111.237 124.002 99.928  1.00 62.18  ? 458 ALA A N   1 
ATOM   3248 C CA  . ALA A 1 477 ? 112.661 123.936 99.612  1.00 62.18  ? 458 ALA A CA  1 
ATOM   3249 C C   . ALA A 1 477 ? 113.206 125.299 99.210  1.00 62.18  ? 458 ALA A C   1 
ATOM   3250 O O   . ALA A 1 477 ? 114.291 125.697 99.647  1.00 62.18  ? 458 ALA A O   1 
ATOM   3251 C CB  . ALA A 1 477 ? 112.907 122.917 98.503  1.00 62.18  ? 458 ALA A CB  1 
ATOM   3252 N N   . LEU A 1 478 ? 112.464 126.029 98.379  1.00 66.29  ? 459 LEU A N   1 
ATOM   3253 C CA  . LEU A 1 478 ? 112.889 127.330 97.887  1.00 66.29  ? 459 LEU A CA  1 
ATOM   3254 C C   . LEU A 1 478 ? 112.927 128.382 98.985  1.00 66.29  ? 459 LEU A C   1 
ATOM   3255 O O   . LEU A 1 478 ? 113.671 129.360 98.860  1.00 66.29  ? 459 LEU A O   1 
ATOM   3256 C CB  . LEU A 1 478 ? 111.942 127.777 96.773  1.00 66.29  ? 459 LEU A CB  1 
ATOM   3257 C CG  . LEU A 1 478 ? 112.239 129.054 95.992  1.00 66.29  ? 459 LEU A CG  1 
ATOM   3258 C CD1 . LEU A 1 478 ? 113.672 129.053 95.521  1.00 66.29  ? 459 LEU A CD1 1 
ATOM   3259 C CD2 . LEU A 1 478 ? 111.286 129.196 94.819  1.00 66.29  ? 459 LEU A CD2 1 
ATOM   3260 N N   . SER A 1 479 ? 112.141 128.208 100.050 1.00 65.58  ? 460 SER A N   1 
ATOM   3261 C CA  . SER A 1 479 ? 112.097 129.186 101.131 1.00 65.58  ? 460 SER A CA  1 
ATOM   3262 C C   . SER A 1 479 ? 113.454 129.437 101.774 1.00 65.58  ? 460 SER A C   1 
ATOM   3263 O O   . SER A 1 479 ? 113.587 130.405 102.529 1.00 65.58  ? 460 SER A O   1 
ATOM   3264 C CB  . SER A 1 479 ? 111.107 128.739 102.205 1.00 65.58  ? 460 SER A CB  1 
ATOM   3265 O OG  . SER A 1 479 ? 111.386 129.371 103.441 1.00 65.58  ? 460 SER A OG  1 
ATOM   3266 N N   . GLY A 1 480 ? 114.451 128.598 101.513 1.00 70.30  ? 461 GLY A N   1 
ATOM   3267 C CA  . GLY A 1 480 ? 115.770 128.797 102.079 1.00 70.30  ? 461 GLY A CA  1 
ATOM   3268 C C   . GLY A 1 480 ? 116.585 129.846 101.355 1.00 70.30  ? 461 GLY A C   1 
ATOM   3269 O O   . GLY A 1 480 ? 117.478 130.462 101.944 1.00 70.30  ? 461 GLY A O   1 
ATOM   3270 N N   . VAL A 1 481 ? 116.284 130.049 100.069 1.00 75.45  ? 462 VAL A N   1 
ATOM   3271 C CA  . VAL A 1 481 ? 117.052 131.006 99.267  1.00 75.45  ? 462 VAL A CA  1 
ATOM   3272 C C   . VAL A 1 481 ? 117.127 132.384 99.910  1.00 75.45  ? 462 VAL A C   1 
ATOM   3273 O O   . VAL A 1 481 ? 118.166 133.046 99.776  1.00 75.45  ? 462 VAL A O   1 
ATOM   3274 C CB  . VAL A 1 481 ? 116.515 131.038 97.830  1.00 75.45  ? 462 VAL A CB  1 
ATOM   3275 C CG1 . VAL A 1 481 ? 117.284 132.025 96.987  1.00 75.45  ? 462 VAL A CG1 1 
ATOM   3276 C CG2 . VAL A 1 481 ? 116.620 129.666 97.222  1.00 75.45  ? 462 VAL A CG2 1 
ATOM   3277 N N   . PRO A 1 482 ? 116.095 132.891 100.595 1.00 80.05  ? 463 PRO A N   1 
ATOM   3278 C CA  . PRO A 1 482 ? 116.294 134.128 101.370 1.00 80.05  ? 463 PRO A CA  1 
ATOM   3279 C C   . PRO A 1 482 ? 117.455 134.054 102.348 1.00 80.05  ? 463 PRO A C   1 
ATOM   3280 O O   . PRO A 1 482 ? 118.330 134.930 102.330 1.00 80.05  ? 463 PRO A O   1 
ATOM   3281 C CB  . PRO A 1 482 ? 114.948 134.298 102.078 1.00 80.05  ? 463 PRO A CB  1 
ATOM   3282 C CG  . PRO A 1 482 ? 113.976 133.749 101.107 1.00 80.05  ? 463 PRO A CG  1 
ATOM   3283 C CD  . PRO A 1 482 ? 114.661 132.574 100.455 1.00 80.05  ? 463 PRO A CD  1 
ATOM   3284 N N   . PHE A 1 483 ? 117.479 133.035 103.213 1.00 81.80  ? 464 PHE A N   1 
ATOM   3285 C CA  . PHE A 1 483 ? 118.596 132.874 104.139 1.00 81.80  ? 464 PHE A CA  1 
ATOM   3286 C C   . PHE A 1 483 ? 119.923 132.793 103.398 1.00 81.80  ? 464 PHE A C   1 
ATOM   3287 O O   . PHE A 1 483 ? 120.924 133.366 103.841 1.00 81.80  ? 464 PHE A O   1 
ATOM   3288 C CB  . PHE A 1 483 ? 118.393 131.629 105.000 1.00 81.80  ? 464 PHE A CB  1 
ATOM   3289 C CG  . PHE A 1 483 ? 117.383 131.804 106.094 1.00 81.80  ? 464 PHE A CG  1 
ATOM   3290 C CD1 . PHE A 1 483 ? 117.713 132.479 107.256 1.00 81.80  ? 464 PHE A CD1 1 
ATOM   3291 C CD2 . PHE A 1 483 ? 116.108 131.285 105.965 1.00 81.80  ? 464 PHE A CD2 1 
ATOM   3292 C CE1 . PHE A 1 483 ? 116.788 132.639 108.269 1.00 81.80  ? 464 PHE A CE1 1 
ATOM   3293 C CE2 . PHE A 1 483 ? 115.177 131.442 106.974 1.00 81.80  ? 464 PHE A CE2 1 
ATOM   3294 C CZ  . PHE A 1 483 ? 115.519 132.120 108.127 1.00 81.80  ? 464 PHE A CZ  1 
ATOM   3295 N N   . TYR A 1 484 ? 119.947 132.095 102.262 1.00 84.41  ? 465 TYR A N   1 
ATOM   3296 C CA  . TYR A 1 484 ? 121.175 131.970 101.483 1.00 84.41  ? 465 TYR A CA  1 
ATOM   3297 C C   . TYR A 1 484 ? 121.664 133.333 101.012 1.00 84.41  ? 465 TYR A C   1 
ATOM   3298 O O   . TYR A 1 484 ? 122.752 133.783 101.387 1.00 84.41  ? 465 TYR A O   1 
ATOM   3299 C CB  . TYR A 1 484 ? 120.942 131.039 100.291 1.00 84.41  ? 465 TYR A CB  1 
ATOM   3300 C CG  . TYR A 1 484 ? 122.182 130.718 99.487  1.00 84.41  ? 465 TYR A CG  1 
ATOM   3301 C CD1 . TYR A 1 484 ? 122.677 131.607 98.548  1.00 84.41  ? 465 TYR A CD1 1 
ATOM   3302 C CD2 . TYR A 1 484 ? 122.837 129.510 99.646  1.00 84.41  ? 465 TYR A CD2 1 
ATOM   3303 C CE1 . TYR A 1 484 ? 123.801 131.311 97.812  1.00 84.41  ? 465 TYR A CE1 1 
ATOM   3304 C CE2 . TYR A 1 484 ? 123.959 129.205 98.915  1.00 84.41  ? 465 TYR A CE2 1 
ATOM   3305 C CZ  . TYR A 1 484 ? 124.437 130.107 97.998  1.00 84.41  ? 465 TYR A CZ  1 
ATOM   3306 O OH  . TYR A 1 484 ? 125.560 129.803 97.265  1.00 84.41  ? 465 TYR A OH  1 
ATOM   3307 N N   . PHE A 1 485 ? 120.868 134.008 100.190 1.00 90.57  ? 466 PHE A N   1 
ATOM   3308 C CA  . PHE A 1 485 ? 121.316 135.262 99.604  1.00 90.57  ? 466 PHE A CA  1 
ATOM   3309 C C   . PHE A 1 485 ? 121.354 136.414 100.597 1.00 90.57  ? 466 PHE A C   1 
ATOM   3310 O O   . PHE A 1 485 ? 121.804 137.501 100.222 1.00 90.57  ? 466 PHE A O   1 
ATOM   3311 C CB  . PHE A 1 485 ? 120.431 135.629 98.414  1.00 90.57  ? 466 PHE A CB  1 
ATOM   3312 C CG  . PHE A 1 485 ? 120.836 134.963 97.132  1.00 90.57  ? 466 PHE A CG  1 
ATOM   3313 C CD1 . PHE A 1 485 ? 122.054 135.248 96.543  1.00 90.57  ? 466 PHE A CD1 1 
ATOM   3314 C CD2 . PHE A 1 485 ? 120.000 134.052 96.517  1.00 90.57  ? 466 PHE A CD2 1 
ATOM   3315 C CE1 . PHE A 1 485 ? 122.428 134.636 95.364  1.00 90.57  ? 466 PHE A CE1 1 
ATOM   3316 C CE2 . PHE A 1 485 ? 120.368 133.437 95.340  1.00 90.57  ? 466 PHE A CE2 1 
ATOM   3317 C CZ  . PHE A 1 485 ? 121.583 133.729 94.763  1.00 90.57  ? 466 PHE A CZ  1 
ATOM   3318 N N   . MET A 1 486 ? 120.906 136.226 101.836 1.00 95.25  ? 467 MET A N   1 
ATOM   3319 C CA  . MET A 1 486 ? 120.949 137.307 102.808 1.00 95.25  ? 467 MET A CA  1 
ATOM   3320 C C   . MET A 1 486 ? 121.976 137.109 103.913 1.00 95.25  ? 467 MET A C   1 
ATOM   3321 O O   . MET A 1 486 ? 122.511 138.099 104.415 1.00 95.25  ? 467 MET A O   1 
ATOM   3322 C CB  . MET A 1 486 ? 119.558 137.499 103.438 1.00 95.25  ? 467 MET A CB  1 
ATOM   3323 C CG  . MET A 1 486 ? 119.442 138.661 104.412 1.00 95.25  ? 467 MET A CG  1 
ATOM   3324 S SD  . MET A 1 486 ? 117.821 138.733 105.199 1.00 95.25  ? 467 MET A SD  1 
ATOM   3325 C CE  . MET A 1 486 ? 118.221 138.207 106.863 1.00 95.25  ? 467 MET A CE  1 
ATOM   3326 N N   . GLY A 1 487 ? 122.281 135.870 104.294 1.00 98.46  ? 468 GLY A N   1 
ATOM   3327 C CA  . GLY A 1 487 ? 123.191 135.637 105.398 1.00 98.46  ? 468 GLY A CA  1 
ATOM   3328 C C   . GLY A 1 487 ? 124.393 134.777 105.067 1.00 98.46  ? 468 GLY A C   1 
ATOM   3329 O O   . GLY A 1 487 ? 125.417 134.852 105.751 1.00 98.46  ? 468 GLY A O   1 
ATOM   3330 N N   . VAL A 1 488 ? 124.289 133.962 104.024 1.00 93.33  ? 469 VAL A N   1 
ATOM   3331 C CA  . VAL A 1 488 ? 125.314 132.977 103.692 1.00 93.33  ? 469 VAL A CA  1 
ATOM   3332 C C   . VAL A 1 488 ? 126.252 133.479 102.604 1.00 93.33  ? 469 VAL A C   1 
ATOM   3333 O O   . VAL A 1 488 ? 127.471 133.363 102.725 1.00 93.33  ? 469 VAL A O   1 
ATOM   3334 C CB  . VAL A 1 488 ? 124.657 131.640 103.283 1.00 93.33  ? 469 VAL A CB  1 
ATOM   3335 C CG1 . VAL A 1 488 ? 125.713 130.648 102.837 1.00 93.33  ? 469 VAL A CG1 1 
ATOM   3336 C CG2 . VAL A 1 488 ? 123.844 131.079 104.431 1.00 93.33  ? 469 VAL A CG2 1 
ATOM   3337 N N   . TYR A 1 489 ? 125.700 134.044 101.528 1.00 103.31 ? 470 TYR A N   1 
ATOM   3338 C CA  . TYR A 1 489 ? 126.519 134.345 100.359 1.00 103.31 ? 470 TYR A CA  1 
ATOM   3339 C C   . TYR A 1 489 ? 127.487 135.490 100.628 1.00 103.31 ? 470 TYR A C   1 
ATOM   3340 O O   . TYR A 1 489 ? 128.622 135.474 100.138 1.00 103.31 ? 470 TYR A O   1 
ATOM   3341 C CB  . TYR A 1 489 ? 125.631 134.666 99.160  1.00 103.31 ? 470 TYR A CB  1 
ATOM   3342 C CG  . TYR A 1 489 ? 126.355 134.582 97.838  1.00 103.31 ? 470 TYR A CG  1 
ATOM   3343 C CD1 . TYR A 1 489 ? 126.486 133.371 97.173  1.00 103.31 ? 470 TYR A CD1 1 
ATOM   3344 C CD2 . TYR A 1 489 ? 126.915 135.711 97.258  1.00 103.31 ? 470 TYR A CD2 1 
ATOM   3345 C CE1 . TYR A 1 489 ? 127.150 133.288 95.964  1.00 103.31 ? 470 TYR A CE1 1 
ATOM   3346 C CE2 . TYR A 1 489 ? 127.581 135.638 96.049  1.00 103.31 ? 470 TYR A CE2 1 
ATOM   3347 C CZ  . TYR A 1 489 ? 127.695 134.425 95.407  1.00 103.31 ? 470 TYR A CZ  1 
ATOM   3348 O OH  . TYR A 1 489 ? 128.358 134.349 94.204  1.00 103.31 ? 470 TYR A OH  1 
ATOM   3349 N N   . LEU A 1 490 ? 127.066 136.489 101.390 1.00 112.51 ? 471 LEU A N   1 
ATOM   3350 C CA  . LEU A 1 490 ? 127.964 137.594 101.699 1.00 112.51 ? 471 LEU A CA  1 
ATOM   3351 C C   . LEU A 1 490 ? 129.032 137.116 102.679 1.00 112.51 ? 471 LEU A C   1 
ATOM   3352 O O   . LEU A 1 490 ? 128.706 136.456 103.673 1.00 112.51 ? 471 LEU A O   1 
ATOM   3353 C CB  . LEU A 1 490 ? 127.194 138.791 102.262 1.00 112.51 ? 471 LEU A CB  1 
ATOM   3354 C CG  . LEU A 1 490 ? 126.793 138.873 103.736 1.00 112.51 ? 471 LEU A CG  1 
ATOM   3355 C CD1 . LEU A 1 490 ? 126.226 140.247 104.050 1.00 112.51 ? 471 LEU A CD1 1 
ATOM   3356 C CD2 . LEU A 1 490 ? 125.787 137.796 104.080 1.00 112.51 ? 471 LEU A CD2 1 
ATOM   3357 N N   . PRO A 1 491 ? 130.307 137.396 102.424 1.00 118.77 ? 472 PRO A N   1 
ATOM   3358 C CA  . PRO A 1 491 ? 131.370 136.819 103.256 1.00 118.77 ? 472 PRO A CA  1 
ATOM   3359 C C   . PRO A 1 491 ? 131.478 137.472 104.623 1.00 118.77 ? 472 PRO A C   1 
ATOM   3360 O O   . PRO A 1 491 ? 130.739 138.410 104.936 1.00 118.77 ? 472 PRO A O   1 
ATOM   3361 C CB  . PRO A 1 491 ? 132.630 137.062 102.420 1.00 118.77 ? 472 PRO A CB  1 
ATOM   3362 C CG  . PRO A 1 491 ? 132.319 138.299 101.651 1.00 118.77 ? 472 PRO A CG  1 
ATOM   3363 C CD  . PRO A 1 491 ? 130.843 138.249 101.350 1.00 118.77 ? 472 PRO A CD  1 
ATOM   3364 N N   . GLU A 1 492 ? 132.397 136.971 105.443 1.00 123.47 ? 473 GLU A N   1 
ATOM   3365 C CA  . GLU A 1 492 ? 132.657 137.567 106.742 1.00 123.47 ? 473 GLU A CA  1 
ATOM   3366 C C   . GLU A 1 492 ? 133.198 138.984 106.575 1.00 123.47 ? 473 GLU A C   1 
ATOM   3367 O O   . GLU A 1 492 ? 133.658 139.381 105.501 1.00 123.47 ? 473 GLU A O   1 
ATOM   3368 C CB  . GLU A 1 492 ? 133.646 136.713 107.535 1.00 123.47 ? 473 GLU A CB  1 
ATOM   3369 C CG  . GLU A 1 492 ? 133.038 135.467 108.163 1.00 123.47 ? 473 GLU A CG  1 
ATOM   3370 C CD  . GLU A 1 492 ? 132.437 135.726 109.532 1.00 123.47 ? 473 GLU A CD  1 
ATOM   3371 O OE1 . GLU A 1 492 ? 132.589 134.862 110.421 1.00 123.47 ? 473 GLU A OE1 1 
ATOM   3372 O OE2 . GLU A 1 492 ? 131.813 136.791 109.721 1.00 123.47 ? 473 GLU A OE2 1 
ATOM   3373 N N   . SER A 1 493 ? 133.133 139.751 107.664 1.00 123.27 ? 474 SER A N   1 
ATOM   3374 C CA  . SER A 1 493 ? 133.493 141.164 107.752 1.00 123.27 ? 474 SER A CA  1 
ATOM   3375 C C   . SER A 1 493 ? 132.554 142.057 106.952 1.00 123.27 ? 474 SER A C   1 
ATOM   3376 O O   . SER A 1 493 ? 132.755 143.277 106.926 1.00 123.27 ? 474 SER A O   1 
ATOM   3377 C CB  . SER A 1 493 ? 134.940 141.439 107.316 1.00 123.27 ? 474 SER A CB  1 
ATOM   3378 O OG  . SER A 1 493 ? 135.119 141.176 105.936 1.00 123.27 ? 474 SER A OG  1 
ATOM   3379 N N   . ARG A 1 494 ? 131.536 141.496 106.295 1.00 121.37 ? 475 ARG A N   1 
ATOM   3380 C CA  . ARG A 1 494 ? 130.518 142.279 105.613 1.00 121.37 ? 475 ARG A CA  1 
ATOM   3381 C C   . ARG A 1 494 ? 129.125 142.089 106.189 1.00 121.37 ? 475 ARG A C   1 
ATOM   3382 O O   . ARG A 1 494 ? 128.246 142.914 105.921 1.00 121.37 ? 475 ARG A O   1 
ATOM   3383 C CB  . ARG A 1 494 ? 130.484 141.938 104.115 1.00 121.37 ? 475 ARG A CB  1 
ATOM   3384 C CG  . ARG A 1 494 ? 131.658 142.483 103.313 1.00 121.37 ? 475 ARG A CG  1 
ATOM   3385 C CD  . ARG A 1 494 ? 132.844 141.535 103.337 1.00 121.37 ? 475 ARG A CD  1 
ATOM   3386 N NE  . ARG A 1 494 ? 134.084 142.197 102.941 1.00 121.37 ? 475 ARG A NE  1 
ATOM   3387 C CZ  . ARG A 1 494 ? 135.273 141.604 102.921 1.00 121.37 ? 475 ARG A CZ  1 
ATOM   3388 N NH1 . ARG A 1 494 ? 135.388 140.332 103.278 1.00 121.37 ? 475 ARG A NH1 1 
ATOM   3389 N NH2 . ARG A 1 494 ? 136.349 142.283 102.549 1.00 121.37 ? 475 ARG A NH2 1 
ATOM   3390 N N   . ARG A 1 495 ? 128.902 141.031 106.965 1.00 116.84 ? 476 ARG A N   1 
ATOM   3391 C CA  . ARG A 1 495 ? 127.654 140.777 107.665 1.00 116.84 ? 476 ARG A CA  1 
ATOM   3392 C C   . ARG A 1 495 ? 127.512 141.734 108.845 1.00 116.84 ? 476 ARG A C   1 
ATOM   3393 O O   . ARG A 1 495 ? 128.513 142.243 109.359 1.00 116.84 ? 476 ARG A O   1 
ATOM   3394 C CB  . ARG A 1 495 ? 127.609 139.331 108.154 1.00 116.84 ? 476 ARG A CB  1 
ATOM   3395 C CG  . ARG A 1 495 ? 128.211 138.331 107.177 1.00 116.84 ? 476 ARG A CG  1 
ATOM   3396 C CD  . ARG A 1 495 ? 127.685 136.926 107.423 1.00 116.84 ? 476 ARG A CD  1 
ATOM   3397 N NE  . ARG A 1 495 ? 128.638 135.903 107.002 1.00 116.84 ? 476 ARG A NE  1 
ATOM   3398 C CZ  . ARG A 1 495 ? 128.343 134.613 106.882 1.00 116.84 ? 476 ARG A CZ  1 
ATOM   3399 N NH1 . ARG A 1 495 ? 129.271 133.751 106.493 1.00 116.84 ? 476 ARG A NH1 1 
ATOM   3400 N NH2 . ARG A 1 495 ? 127.120 134.184 107.155 1.00 116.84 ? 476 ARG A NH2 1 
ATOM   3401 N N   . PRO A 1 496 ? 126.285 142.012 109.288 1.00 119.56 ? 477 PRO A N   1 
ATOM   3402 C CA  . PRO A 1 496 ? 126.094 143.022 110.336 1.00 119.56 ? 477 PRO A CA  1 
ATOM   3403 C C   . PRO A 1 496 ? 126.808 142.645 111.626 1.00 119.56 ? 477 PRO A C   1 
ATOM   3404 O O   . PRO A 1 496 ? 126.932 141.468 111.973 1.00 119.56 ? 477 PRO A O   1 
ATOM   3405 C CB  . PRO A 1 496 ? 124.573 143.060 110.521 1.00 119.56 ? 477 PRO A CB  1 
ATOM   3406 C CG  . PRO A 1 496 ? 124.018 142.499 109.259 1.00 119.56 ? 477 PRO A CG  1 
ATOM   3407 C CD  . PRO A 1 496 ? 125.003 141.474 108.803 1.00 119.56 ? 477 PRO A CD  1 
ATOM   3408 N N   . LEU A 1 497 ? 127.287 143.667 112.338 1.00 121.08 ? 478 LEU A N   1 
ATOM   3409 C CA  . LEU A 1 497 ? 128.080 143.430 113.538 1.00 121.08 ? 478 LEU A CA  1 
ATOM   3410 C C   . LEU A 1 497 ? 127.231 142.913 114.692 1.00 121.08 ? 478 LEU A C   1 
ATOM   3411 O O   . LEU A 1 497 ? 127.709 142.100 115.489 1.00 121.08 ? 478 LEU A O   1 
ATOM   3412 C CB  . LEU A 1 497 ? 128.817 144.712 113.937 1.00 121.08 ? 478 LEU A CB  1 
ATOM   3413 C CG  . LEU A 1 497 ? 128.020 145.982 114.263 1.00 121.08 ? 478 LEU A CG  1 
ATOM   3414 C CD1 . LEU A 1 497 ? 127.615 146.052 115.733 1.00 121.08 ? 478 LEU A CD1 1 
ATOM   3415 C CD2 . LEU A 1 497 ? 128.807 147.223 113.866 1.00 121.08 ? 478 LEU A CD2 1 
ATOM   3416 N N   . PHE A 1 498 ? 125.976 143.355 114.795 1.00 120.30 ? 479 PHE A N   1 
ATOM   3417 C CA  . PHE A 1 498 ? 125.163 142.984 115.950 1.00 120.30 ? 479 PHE A CA  1 
ATOM   3418 C C   . PHE A 1 498 ? 124.724 141.526 115.878 1.00 120.30 ? 479 PHE A C   1 
ATOM   3419 O O   . PHE A 1 498 ? 124.793 140.801 116.879 1.00 120.30 ? 479 PHE A O   1 
ATOM   3420 C CB  . PHE A 1 498 ? 123.950 143.910 116.066 1.00 120.30 ? 479 PHE A CB  1 
ATOM   3421 C CG  . PHE A 1 498 ? 123.225 144.141 114.768 1.00 120.30 ? 479 PHE A CG  1 
ATOM   3422 C CD1 . PHE A 1 498 ? 123.644 145.127 113.887 1.00 120.30 ? 479 PHE A CD1 1 
ATOM   3423 C CD2 . PHE A 1 498 ? 122.115 143.382 114.435 1.00 120.30 ? 479 PHE A CD2 1 
ATOM   3424 C CE1 . PHE A 1 498 ? 122.976 145.342 112.695 1.00 120.30 ? 479 PHE A CE1 1 
ATOM   3425 C CE2 . PHE A 1 498 ? 121.443 143.593 113.245 1.00 120.30 ? 479 PHE A CE2 1 
ATOM   3426 C CZ  . PHE A 1 498 ? 121.874 144.575 112.374 1.00 120.30 ? 479 PHE A CZ  1 
ATOM   3427 N N   . ILE A 1 499 ? 124.279 141.074 114.704 1.00 116.66 ? 480 ILE A N   1 
ATOM   3428 C CA  . ILE A 1 499 ? 123.849 139.686 114.573 1.00 116.66 ? 480 ILE A CA  1 
ATOM   3429 C C   . ILE A 1 499 ? 125.036 138.745 114.729 1.00 116.66 ? 480 ILE A C   1 
ATOM   3430 O O   . ILE A 1 499 ? 124.929 137.690 115.364 1.00 116.66 ? 480 ILE A O   1 
ATOM   3431 C CB  . ILE A 1 499 ? 123.117 139.470 113.236 1.00 116.66 ? 480 ILE A CB  1 
ATOM   3432 C CG1 . ILE A 1 499 ? 122.718 138.002 113.076 1.00 116.66 ? 480 ILE A CG1 1 
ATOM   3433 C CG2 . ILE A 1 499 ? 123.972 139.922 112.068 1.00 116.66 ? 480 ILE A CG2 1 
ATOM   3434 C CD1 . ILE A 1 499 ? 121.818 137.493 114.180 1.00 116.66 ? 480 ILE A CD1 1 
ATOM   3435 N N   . ARG A 1 500 ? 126.192 139.116 114.179 1.00 117.46 ? 481 ARG A N   1 
ATOM   3436 C CA  . ARG A 1 500 ? 127.371 138.273 114.339 1.00 117.46 ? 481 ARG A CA  1 
ATOM   3437 C C   . ARG A 1 500 ? 127.854 138.274 115.782 1.00 117.46 ? 481 ARG A C   1 
ATOM   3438 O O   . ARG A 1 500 ? 128.338 137.253 116.278 1.00 117.46 ? 481 ARG A O   1 
ATOM   3439 C CB  . ARG A 1 500 ? 128.475 138.729 113.389 1.00 117.46 ? 481 ARG A CB  1 
ATOM   3440 C CG  . ARG A 1 500 ? 128.291 138.202 111.979 1.00 117.46 ? 481 ARG A CG  1 
ATOM   3441 C CD  . ARG A 1 500 ? 129.494 138.489 111.111 1.00 117.46 ? 481 ARG A CD  1 
ATOM   3442 N NE  . ARG A 1 500 ? 129.683 139.920 110.900 1.00 117.46 ? 481 ARG A NE  1 
ATOM   3443 C CZ  . ARG A 1 500 ? 130.819 140.463 110.480 1.00 117.46 ? 481 ARG A CZ  1 
ATOM   3444 N NH1 . ARG A 1 500 ? 131.861 139.689 110.221 1.00 117.46 ? 481 ARG A NH1 1 
ATOM   3445 N NH2 . ARG A 1 500 ? 130.912 141.775 110.313 1.00 117.46 ? 481 ARG A NH2 1 
ATOM   3446 N N   . ASN A 1 501 ? 127.695 139.396 116.486 1.00 116.56 ? 482 ASN A N   1 
ATOM   3447 C CA  . ASN A 1 501 ? 128.097 139.449 117.886 1.00 116.56 ? 482 ASN A CA  1 
ATOM   3448 C C   . ASN A 1 501 ? 127.192 138.576 118.747 1.00 116.56 ? 482 ASN A C   1 
ATOM   3449 O O   . ASN A 1 501 ? 127.665 137.866 119.643 1.00 116.56 ? 482 ASN A O   1 
ATOM   3450 C CB  . ASN A 1 501 ? 128.086 140.896 118.379 1.00 116.56 ? 482 ASN A CB  1 
ATOM   3451 C CG  . ASN A 1 501 ? 128.877 141.087 119.661 1.00 116.56 ? 482 ASN A CG  1 
ATOM   3452 O OD1 . ASN A 1 501 ? 129.095 140.143 120.420 1.00 116.56 ? 482 ASN A OD1 1 
ATOM   3453 N ND2 . ASN A 1 501 ? 129.310 142.317 119.908 1.00 116.56 ? 482 ASN A ND2 1 
ATOM   3454 N N   . VAL A 1 502 ? 125.882 138.608 118.488 1.00 113.58 ? 483 VAL A N   1 
ATOM   3455 C CA  . VAL A 1 502 ? 124.993 137.774 119.291 1.00 113.58 ? 483 VAL A CA  1 
ATOM   3456 C C   . VAL A 1 502 ? 125.169 136.303 118.927 1.00 113.58 ? 483 VAL A C   1 
ATOM   3457 O O   . VAL A 1 502 ? 125.063 135.429 119.795 1.00 113.58 ? 483 VAL A O   1 
ATOM   3458 C CB  . VAL A 1 502 ? 123.526 138.230 119.162 1.00 113.58 ? 483 VAL A CB  1 
ATOM   3459 C CG1 . VAL A 1 502 ? 123.051 138.166 117.731 1.00 113.58 ? 483 VAL A CG1 1 
ATOM   3460 C CG2 . VAL A 1 502 ? 122.626 137.400 120.066 1.00 113.58 ? 483 VAL A CG2 1 
ATOM   3461 N N   . LEU A 1 503 ? 125.472 135.998 117.660 1.00 111.02 ? 484 LEU A N   1 
ATOM   3462 C CA  . LEU A 1 503 ? 125.805 134.620 117.309 1.00 111.02 ? 484 LEU A CA  1 
ATOM   3463 C C   . LEU A 1 503 ? 127.083 134.174 118.000 1.00 111.02 ? 484 LEU A C   1 
ATOM   3464 O O   . LEU A 1 503 ? 127.184 133.028 118.442 1.00 111.02 ? 484 LEU A O   1 
ATOM   3465 C CB  . LEU A 1 503 ? 125.933 134.461 115.795 1.00 111.02 ? 484 LEU A CB  1 
ATOM   3466 C CG  . LEU A 1 503 ? 124.634 134.480 114.992 1.00 111.02 ? 484 LEU A CG  1 
ATOM   3467 C CD1 . LEU A 1 503 ? 124.923 134.448 113.501 1.00 111.02 ? 484 LEU A CD1 1 
ATOM   3468 C CD2 . LEU A 1 503 ? 123.764 133.303 115.393 1.00 111.02 ? 484 LEU A CD2 1 
ATOM   3469 N N   . ALA A 1 504 ? 128.068 135.067 118.109 1.00 114.49 ? 485 ALA A N   1 
ATOM   3470 C CA  . ALA A 1 504 ? 129.281 134.747 118.853 1.00 114.49 ? 485 ALA A CA  1 
ATOM   3471 C C   . ALA A 1 504 ? 128.969 134.446 120.311 1.00 114.49 ? 485 ALA A C   1 
ATOM   3472 O O   . ALA A 1 504 ? 129.451 133.451 120.864 1.00 114.49 ? 485 ALA A O   1 
ATOM   3473 C CB  . ALA A 1 504 ? 130.276 135.901 118.757 1.00 114.49 ? 485 ALA A CB  1 
ATOM   3474 N N   . ALA A 1 505 ? 128.172 135.305 120.948 1.00 109.71 ? 486 ALA A N   1 
ATOM   3475 C CA  . ALA A 1 505 ? 127.831 135.093 122.350 1.00 109.71 ? 486 ALA A CA  1 
ATOM   3476 C C   . ALA A 1 505 ? 127.081 133.782 122.544 1.00 109.71 ? 486 ALA A C   1 
ATOM   3477 O O   . ALA A 1 505 ? 127.387 133.016 123.466 1.00 109.71 ? 486 ALA A O   1 
ATOM   3478 C CB  . ALA A 1 505 ? 127.007 136.268 122.873 1.00 109.71 ? 486 ALA A CB  1 
ATOM   3479 N N   . ILE A 1 506 ? 126.120 133.486 121.667 1.00 108.73 ? 487 ILE A N   1 
ATOM   3480 C CA  . ILE A 1 506 ? 125.323 132.282 121.860 1.00 108.73 ? 487 ILE A CA  1 
ATOM   3481 C C   . ILE A 1 506 ? 126.130 131.038 121.514 1.00 108.73 ? 487 ILE A C   1 
ATOM   3482 O O   . ILE A 1 506 ? 125.950 129.986 122.137 1.00 108.73 ? 487 ILE A O   1 
ATOM   3483 C CB  . ILE A 1 506 ? 124.011 132.366 121.055 1.00 108.73 ? 487 ILE A CB  1 
ATOM   3484 C CG1 . ILE A 1 506 ? 122.972 131.399 121.628 1.00 108.73 ? 487 ILE A CG1 1 
ATOM   3485 C CG2 . ILE A 1 506 ? 124.248 132.094 119.577 1.00 108.73 ? 487 ILE A CG2 1 
ATOM   3486 C CD1 . ILE A 1 506 ? 122.528 131.735 123.036 1.00 108.73 ? 487 ILE A CD1 1 
ATOM   3487 N N   . THR A 1 507 ? 127.046 131.133 120.547 1.00 105.62 ? 488 THR A N   1 
ATOM   3488 C CA  . THR A 1 507 ? 127.922 130.011 120.241 1.00 105.62 ? 488 THR A CA  1 
ATOM   3489 C C   . THR A 1 507 ? 128.848 129.726 121.410 1.00 105.62 ? 488 THR A C   1 
ATOM   3490 O O   . THR A 1 507 ? 129.035 128.569 121.795 1.00 105.62 ? 488 THR A O   1 
ATOM   3491 C CB  . THR A 1 507 ? 128.725 130.300 118.971 1.00 105.62 ? 488 THR A CB  1 
ATOM   3492 O OG1 . THR A 1 507 ? 127.859 130.241 117.832 1.00 105.62 ? 488 THR A OG1 1 
ATOM   3493 C CG2 . THR A 1 507 ? 129.841 129.286 118.800 1.00 105.62 ? 488 THR A CG2 1 
ATOM   3494 N N   . ARG A 1 508 ? 129.423 130.775 122.002 1.00 104.31 ? 489 ARG A N   1 
ATOM   3495 C CA  . ARG A 1 508 ? 130.241 130.589 123.195 1.00 104.31 ? 489 ARG A CA  1 
ATOM   3496 C C   . ARG A 1 508 ? 129.432 129.950 124.314 1.00 104.31 ? 489 ARG A C   1 
ATOM   3497 O O   . ARG A 1 508 ? 129.903 129.017 124.975 1.00 104.31 ? 489 ARG A O   1 
ATOM   3498 C CB  . ARG A 1 508 ? 130.821 131.927 123.649 1.00 104.31 ? 489 ARG A CB  1 
ATOM   3499 C CG  . ARG A 1 508 ? 132.070 131.807 124.505 1.00 104.31 ? 489 ARG A CG  1 
ATOM   3500 C CD  . ARG A 1 508 ? 131.748 131.983 125.982 1.00 104.31 ? 489 ARG A CD  1 
ATOM   3501 N NE  . ARG A 1 508 ? 131.241 133.320 126.277 1.00 104.31 ? 489 ARG A NE  1 
ATOM   3502 C CZ  . ARG A 1 508 ? 132.010 134.374 126.530 1.00 104.31 ? 489 ARG A CZ  1 
ATOM   3503 N NH1 . ARG A 1 508 ? 133.330 134.251 126.527 1.00 104.31 ? 489 ARG A NH1 1 
ATOM   3504 N NH2 . ARG A 1 508 ? 131.459 135.552 126.788 1.00 104.31 ? 489 ARG A NH2 1 
ATOM   3505 N N   . GLY A 1 509 ? 128.205 130.420 124.523 1.00 98.92  ? 490 GLY A N   1 
ATOM   3506 C CA  . GLY A 1 509 ? 127.331 129.841 125.524 1.00 98.92  ? 490 GLY A CA  1 
ATOM   3507 C C   . GLY A 1 509 ? 127.088 128.357 125.336 1.00 98.92  ? 490 GLY A C   1 
ATOM   3508 O O   . GLY A 1 509 ? 127.410 127.554 126.217 1.00 98.92  ? 490 GLY A O   1 
ATOM   3509 N N   . THR A 1 510 ? 126.526 127.976 124.187 1.00 94.36  ? 491 THR A N   1 
ATOM   3510 C CA  . THR A 1 510 ? 126.184 126.572 123.976 1.00 94.36  ? 491 THR A CA  1 
ATOM   3511 C C   . THR A 1 510 ? 127.423 125.698 123.817 1.00 94.36  ? 491 THR A C   1 
ATOM   3512 O O   . THR A 1 510 ? 127.366 124.495 124.092 1.00 94.36  ? 491 THR A O   1 
ATOM   3513 C CB  . THR A 1 510 ? 125.269 126.417 122.763 1.00 94.36  ? 491 THR A CB  1 
ATOM   3514 O OG1 . THR A 1 510 ? 125.058 125.024 122.497 1.00 94.36  ? 491 THR A OG1 1 
ATOM   3515 C CG2 . THR A 1 510 ? 125.886 127.059 121.552 1.00 94.36  ? 491 THR A CG2 1 
ATOM   3516 N N   . GLN A 1 511 ? 128.551 126.275 123.405 1.00 97.25  ? 492 GLN A N   1 
ATOM   3517 C CA  . GLN A 1 511 ? 129.780 125.503 123.292 1.00 97.25  ? 492 GLN A CA  1 
ATOM   3518 C C   . GLN A 1 511 ? 130.376 125.233 124.665 1.00 97.25  ? 492 GLN A C   1 
ATOM   3519 O O   . GLN A 1 511 ? 130.923 124.153 124.911 1.00 97.25  ? 492 GLN A O   1 
ATOM   3520 C CB  . GLN A 1 511 ? 130.763 126.249 122.391 1.00 97.25  ? 492 GLN A CB  1 
ATOM   3521 C CG  . GLN A 1 511 ? 132.210 125.843 122.527 1.00 97.25  ? 492 GLN A CG  1 
ATOM   3522 C CD  . GLN A 1 511 ? 133.135 126.782 121.783 1.00 97.25  ? 492 GLN A CD  1 
ATOM   3523 O OE1 . GLN A 1 511 ? 132.683 127.691 121.089 1.00 97.25  ? 492 GLN A OE1 1 
ATOM   3524 N NE2 . GLN A 1 511 ? 134.436 126.570 121.924 1.00 97.25  ? 492 GLN A NE2 1 
ATOM   3525 N N   . GLN A 1 512 ? 130.271 126.201 125.576 1.00 100.11 ? 493 GLN A N   1 
ATOM   3526 C CA  . GLN A 1 512 ? 130.668 125.956 126.955 1.00 100.11 ? 493 GLN A CA  1 
ATOM   3527 C C   . GLN A 1 512 ? 129.704 125.006 127.648 1.00 100.11 ? 493 GLN A C   1 
ATOM   3528 O O   . GLN A 1 512 ? 130.109 124.249 128.536 1.00 100.11 ? 493 GLN A O   1 
ATOM   3529 C CB  . GLN A 1 512 ? 130.745 127.279 127.711 1.00 100.11 ? 493 GLN A CB  1 
ATOM   3530 C CG  . GLN A 1 512 ? 131.603 127.240 128.955 1.00 100.11 ? 493 GLN A CG  1 
ATOM   3531 C CD  . GLN A 1 512 ? 132.367 128.530 129.176 1.00 100.11 ? 493 GLN A CD  1 
ATOM   3532 O OE1 . GLN A 1 512 ? 132.592 129.301 128.244 1.00 100.11 ? 493 GLN A OE1 1 
ATOM   3533 N NE2 . GLN A 1 512 ? 132.761 128.776 130.420 1.00 100.11 ? 493 GLN A NE2 1 
ATOM   3534 N N   . LEU A 1 513 ? 128.441 125.027 127.235 1.00 93.39  ? 494 LEU A N   1 
ATOM   3535 C CA  . LEU A 1 513 ? 127.436 124.172 127.859 1.00 93.39  ? 494 LEU A CA  1 
ATOM   3536 C C   . LEU A 1 513 ? 127.410 122.785 127.228 1.00 93.39  ? 494 LEU A C   1 
ATOM   3537 O O   . LEU A 1 513 ? 127.487 121.778 127.932 1.00 93.39  ? 494 LEU A O   1 
ATOM   3538 C CB  . LEU A 1 513 ? 126.056 124.827 127.770 1.00 93.39  ? 494 LEU A CB  1 
ATOM   3539 C CG  . LEU A 1 513 ? 124.921 124.206 128.589 1.00 93.39  ? 494 LEU A CG  1 
ATOM   3540 C CD1 . LEU A 1 513 ? 123.842 125.234 128.886 1.00 93.39  ? 494 LEU A CD1 1 
ATOM   3541 C CD2 . LEU A 1 513 ? 124.331 122.978 127.911 1.00 93.39  ? 494 LEU A CD2 1 
ATOM   3542 N N   . CYS A 1 514 ? 127.307 122.725 125.904 1.00 91.82  ? 495 CYS A N   1 
ATOM   3543 C CA  . CYS A 1 514 ? 127.266 121.438 125.211 1.00 91.82  ? 495 CYS A CA  1 
ATOM   3544 C C   . CYS A 1 514 ? 128.594 120.711 125.334 1.00 91.82  ? 495 CYS A C   1 
ATOM   3545 O O   . CYS A 1 514 ? 128.702 119.547 124.947 1.00 91.82  ? 495 CYS A O   1 
ATOM   3546 C CB  . CYS A 1 514 ? 126.897 121.615 123.736 1.00 91.82  ? 495 CYS A CB  1 
ATOM   3547 S SG  . CYS A 1 514 ? 125.214 122.213 123.458 1.00 91.82  ? 495 CYS A SG  1 
ATOM   3548 N N   . PHE A 1 515 ? 129.606 121.393 125.861 1.00 92.03  ? 496 PHE A N   1 
ATOM   3549 C CA  . PHE A 1 515 ? 130.898 120.756 126.068 1.00 92.03  ? 496 PHE A CA  1 
ATOM   3550 C C   . PHE A 1 515 ? 131.456 120.241 124.752 1.00 92.03  ? 496 PHE A C   1 
ATOM   3551 O O   . PHE A 1 515 ? 131.828 119.073 124.643 1.00 92.03  ? 496 PHE A O   1 
ATOM   3552 C CB  . PHE A 1 515 ? 130.753 119.607 127.064 1.00 92.03  ? 496 PHE A CB  1 
ATOM   3553 C CG  . PHE A 1 515 ? 132.002 119.307 127.833 1.00 92.03  ? 496 PHE A CG  1 
ATOM   3554 C CD1 . PHE A 1 515 ? 132.131 119.720 129.147 1.00 92.03  ? 496 PHE A CD1 1 
ATOM   3555 C CD2 . PHE A 1 515 ? 133.045 118.613 127.247 1.00 92.03  ? 496 PHE A CD2 1 
ATOM   3556 C CE1 . PHE A 1 515 ? 133.277 119.444 129.865 1.00 92.03  ? 496 PHE A CE1 1 
ATOM   3557 C CE2 . PHE A 1 515 ? 134.194 118.335 127.956 1.00 92.03  ? 496 PHE A CE2 1 
ATOM   3558 C CZ  . PHE A 1 515 ? 134.309 118.750 129.268 1.00 92.03  ? 496 PHE A CZ  1 
ATOM   3559 N N   . CYS A 1 516 ? 131.506 121.106 123.747 1.00 79.62  ? 497 CYS A N   1 
ATOM   3560 C CA  . CYS A 1 516 ? 132.000 120.693 122.438 1.00 79.62  ? 497 CYS A CA  1 
ATOM   3561 C C   . CYS A 1 516 ? 132.965 121.707 121.846 1.00 79.62  ? 497 CYS A C   1 
ATOM   3562 O O   . CYS A 1 516 ? 132.971 122.871 122.245 1.00 79.62  ? 497 CYS A O   1 
ATOM   3563 C CB  . CYS A 1 516 ? 130.831 120.463 121.480 1.00 79.62  ? 497 CYS A CB  1 
ATOM   3564 S SG  . CYS A 1 516 ? 129.754 119.095 121.955 1.00 79.62  ? 497 CYS A SG  1 
ATOM   3565 N N   . VAL A 1 517 ? 133.782 121.268 120.895 1.00 78.73  ? 498 VAL A N   1 
ATOM   3566 C CA  . VAL A 1 517 ? 134.745 122.164 120.264 1.00 78.73  ? 498 VAL A CA  1 
ATOM   3567 C C   . VAL A 1 517 ? 134.753 122.006 118.755 1.00 78.73  ? 498 VAL A C   1 
ATOM   3568 O O   . VAL A 1 517 ? 134.305 120.988 118.228 1.00 78.73  ? 498 VAL A O   1 
ATOM   3569 C CB  . VAL A 1 517 ? 136.174 121.916 120.780 1.00 78.73  ? 498 VAL A CB  1 
ATOM   3570 C CG1 . VAL A 1 517 ? 136.332 122.439 122.198 1.00 78.73  ? 498 VAL A CG1 1 
ATOM   3571 C CG2 . VAL A 1 517 ? 136.523 120.439 120.690 1.00 78.73  ? 498 VAL A CG2 1 
ATOM   3572 N N   . LEU A 1 518 ? 135.267 123.012 118.058 1.00 85.19  ? 499 LEU A N   1 
ATOM   3573 C CA  . LEU A 1 518 ? 135.350 122.944 116.605 1.00 85.19  ? 499 LEU A CA  1 
ATOM   3574 C C   . LEU A 1 518 ? 136.349 121.883 116.176 1.00 85.19  ? 499 LEU A C   1 
ATOM   3575 O O   . LEU A 1 518 ? 137.287 121.572 116.912 1.00 85.19  ? 499 LEU A O   1 
ATOM   3576 C CB  . LEU A 1 518 ? 135.744 124.304 116.025 1.00 85.19  ? 499 LEU A CB  1 
ATOM   3577 C CG  . LEU A 1 518 ? 137.102 124.884 116.432 1.00 85.19  ? 499 LEU A CG  1 
ATOM   3578 C CD1 . LEU A 1 518 ? 137.511 126.005 115.488 1.00 85.19  ? 499 LEU A CD1 1 
ATOM   3579 C CD2 . LEU A 1 518 ? 137.112 125.365 117.876 1.00 85.19  ? 499 LEU A CD2 1 
ATOM   3580 N N   . THR A 1 519 ? 136.154 121.323 114.988 1.00 84.71  ? 500 THR A N   1 
ATOM   3581 C CA  . THR A 1 519 ? 137.051 120.282 114.497 1.00 84.71  ? 500 THR A CA  1 
ATOM   3582 C C   . THR A 1 519 ? 138.470 120.808 114.322 1.00 84.71  ? 500 THR A C   1 
ATOM   3583 O O   . THR A 1 519 ? 138.666 121.988 114.033 1.00 84.71  ? 500 THR A O   1 
ATOM   3584 C CB  . THR A 1 519 ? 136.551 119.695 113.163 1.00 84.71  ? 500 THR A CB  1 
ATOM   3585 O OG1 . THR A 1 519 ? 135.175 119.315 113.292 1.00 84.71  ? 500 THR A OG1 1 
ATOM   3586 C CG2 . THR A 1 519 ? 137.373 118.478 112.768 1.00 84.71  ? 500 THR A CG2 1 
ATOM   3587 N N   . GLU A 1 520 ? 139.459 119.939 114.500 1.00 93.28  ? 501 GLU A N   1 
ATOM   3588 C CA  . GLU A 1 520 ? 140.855 120.340 114.362 1.00 93.28  ? 501 GLU A CA  1 
ATOM   3589 C C   . GLU A 1 520 ? 141.579 119.522 113.297 1.00 93.28  ? 501 GLU A C   1 
ATOM   3590 O O   . GLU A 1 520 ? 141.028 118.581 112.733 1.00 93.28  ? 501 GLU A O   1 
ATOM   3591 C CB  . GLU A 1 520 ? 141.579 120.209 115.701 1.00 93.28  ? 501 GLU A CB  1 
ATOM   3592 C CG  . GLU A 1 520 ? 140.903 120.953 116.843 1.00 93.28  ? 501 GLU A CG  1 
ATOM   3593 C CD  . GLU A 1 520 ? 141.897 121.514 117.837 1.00 93.28  ? 501 GLU A CD  1 
ATOM   3594 O OE1 . GLU A 1 520 ? 141.688 122.650 118.308 1.00 93.28  ? 501 GLU A OE1 1 
ATOM   3595 O OE2 . GLU A 1 520 ? 142.891 120.822 118.140 1.00 93.28  ? 501 GLU A OE2 1 
ATOM   3596 N N   . LYS B 2 172 ? 137.883 139.775 115.536 1.00 121.65 ? 161 LYS B N   1 
ATOM   3597 C CA  . LYS B 2 172 ? 136.478 139.398 115.609 1.00 121.65 ? 161 LYS B CA  1 
ATOM   3598 C C   . LYS B 2 172 ? 136.251 138.413 116.747 1.00 121.65 ? 161 LYS B C   1 
ATOM   3599 O O   . LYS B 2 172 ? 136.460 138.749 117.912 1.00 121.65 ? 161 LYS B O   1 
ATOM   3600 C CB  . LYS B 2 172 ? 136.017 138.797 114.280 1.00 121.65 ? 161 LYS B CB  1 
ATOM   3601 C CG  . LYS B 2 172 ? 134.512 138.621 114.159 1.00 121.65 ? 161 LYS B CG  1 
ATOM   3602 C CD  . LYS B 2 172 ? 134.135 138.028 112.813 1.00 121.65 ? 161 LYS B CD  1 
ATOM   3603 C CE  . LYS B 2 172 ? 132.632 137.859 112.703 1.00 121.65 ? 161 LYS B CE  1 
ATOM   3604 N NZ  . LYS B 2 172 ? 131.930 139.123 113.059 1.00 121.65 ? 161 LYS B NZ  1 
ATOM   3605 N N   . PHE B 2 173 ? 135.824 137.199 116.415 1.00 123.25 ? 162 PHE B N   1 
ATOM   3606 C CA  . PHE B 2 173 ? 135.581 136.184 117.435 1.00 123.25 ? 162 PHE B CA  1 
ATOM   3607 C C   . PHE B 2 173 ? 135.507 134.795 116.824 1.00 123.25 ? 162 PHE B C   1 
ATOM   3608 O O   . PHE B 2 173 ? 135.239 134.651 115.631 1.00 123.25 ? 162 PHE B O   1 
ATOM   3609 C CB  . PHE B 2 173 ? 134.294 136.491 118.199 1.00 123.25 ? 162 PHE B CB  1 
ATOM   3610 C CG  . PHE B 2 173 ? 133.186 137.012 117.333 1.00 123.25 ? 162 PHE B CG  1 
ATOM   3611 C CD1 . PHE B 2 173 ? 132.563 136.189 116.411 1.00 123.25 ? 162 PHE B CD1 1 
ATOM   3612 C CD2 . PHE B 2 173 ? 132.764 138.325 117.445 1.00 123.25 ? 162 PHE B CD2 1 
ATOM   3613 C CE1 . PHE B 2 173 ? 131.540 136.667 115.616 1.00 123.25 ? 162 PHE B CE1 1 
ATOM   3614 C CE2 . PHE B 2 173 ? 131.743 138.810 116.653 1.00 123.25 ? 162 PHE B CE2 1 
ATOM   3615 C CZ  . PHE B 2 173 ? 131.130 137.979 115.738 1.00 123.25 ? 162 PHE B CZ  1 
ATOM   3616 N N   . THR B 2 174 ? 135.740 133.771 117.637 1.00 119.75 ? 163 THR B N   1 
ATOM   3617 C CA  . THR B 2 174 ? 135.694 132.398 117.149 1.00 119.75 ? 163 THR B CA  1 
ATOM   3618 C C   . THR B 2 174 ? 135.345 131.462 118.295 1.00 119.75 ? 163 THR B C   1 
ATOM   3619 O O   . THR B 2 174 ? 135.505 131.822 119.462 1.00 119.75 ? 163 THR B O   1 
ATOM   3620 C CB  . THR B 2 174 ? 137.039 131.976 116.527 1.00 119.75 ? 163 THR B CB  1 
ATOM   3621 O OG1 . THR B 2 174 ? 137.473 132.972 115.592 1.00 119.75 ? 163 THR B OG1 1 
ATOM   3622 C CG2 . THR B 2 174 ? 136.910 130.638 115.809 1.00 119.75 ? 163 THR B CG2 1 
ATOM   3623 N N   . GLY B 2 175 ? 134.871 130.263 117.975 1.00 113.05 ? 164 GLY B N   1 
ATOM   3624 C CA  . GLY B 2 175 ? 134.553 129.299 119.010 1.00 113.05 ? 164 GLY B CA  1 
ATOM   3625 C C   . GLY B 2 175 ? 135.739 129.141 119.935 1.00 113.05 ? 164 GLY B C   1 
ATOM   3626 O O   . GLY B 2 175 ? 136.866 128.960 119.475 1.00 113.05 ? 164 GLY B O   1 
ATOM   3627 N N   . LEU B 2 176 ? 135.497 129.207 121.239 1.00 113.71 ? 165 LEU B N   1 
ATOM   3628 C CA  . LEU B 2 176 ? 136.589 129.120 122.203 1.00 113.71 ? 165 LEU B CA  1 
ATOM   3629 C C   . LEU B 2 176 ? 137.431 127.877 121.981 1.00 113.71 ? 165 LEU B C   1 
ATOM   3630 O O   . LEU B 2 176 ? 136.906 126.801 121.703 1.00 113.71 ? 165 LEU B O   1 
ATOM   3631 C CB  . LEU B 2 176 ? 136.048 129.126 123.634 1.00 113.71 ? 165 LEU B CB  1 
ATOM   3632 C CG  . LEU B 2 176 ? 135.930 130.496 124.303 1.00 113.71 ? 165 LEU B CG  1 
ATOM   3633 C CD1 . LEU B 2 176 ? 135.258 131.505 123.386 1.00 113.71 ? 165 LEU B CD1 1 
ATOM   3634 C CD2 . LEU B 2 176 ? 135.204 130.392 125.636 1.00 113.71 ? 165 LEU B CD2 1 
ATOM   3635 N N   . SER B 2 177 ? 138.744 128.023 122.105 1.00 109.93 ? 166 SER B N   1 
ATOM   3636 C CA  . SER B 2 177 ? 139.623 126.877 121.949 1.00 109.93 ? 166 SER B CA  1 
ATOM   3637 C C   . SER B 2 177 ? 139.378 125.900 123.081 1.00 109.93 ? 166 SER B C   1 
ATOM   3638 O O   . SER B 2 177 ? 138.784 126.252 124.102 1.00 109.93 ? 166 SER B O   1 
ATOM   3639 C CB  . SER B 2 177 ? 141.088 127.311 121.937 1.00 109.93 ? 166 SER B CB  1 
ATOM   3640 O OG  . SER B 2 177 ? 141.479 127.821 123.200 1.00 109.93 ? 166 SER B OG  1 
ATOM   3641 N N   . LYS B 2 178 ? 139.839 124.669 122.911 1.00 104.79 ? 167 LYS B N   1 
ATOM   3642 C CA  . LYS B 2 178 ? 139.656 123.666 123.945 1.00 104.79 ? 167 LYS B CA  1 
ATOM   3643 C C   . LYS B 2 178 ? 140.261 124.166 125.248 1.00 104.79 ? 167 LYS B C   1 
ATOM   3644 O O   . LYS B 2 178 ? 139.834 123.769 126.328 1.00 104.79 ? 167 LYS B O   1 
ATOM   3645 C CB  . LYS B 2 178 ? 140.293 122.346 123.522 1.00 104.79 ? 167 LYS B CB  1 
ATOM   3646 C CG  . LYS B 2 178 ? 139.846 121.147 124.338 1.00 104.79 ? 167 LYS B CG  1 
ATOM   3647 C CD  . LYS B 2 178 ? 140.526 119.866 123.881 1.00 104.79 ? 167 LYS B CD  1 
ATOM   3648 C CE  . LYS B 2 178 ? 141.996 119.827 124.270 1.00 104.79 ? 167 LYS B CE  1 
ATOM   3649 N NZ  . LYS B 2 178 ? 142.845 120.761 123.478 1.00 104.79 ? 167 LYS B NZ  1 
ATOM   3650 N N   . GLU B 2 179 ? 141.246 125.052 125.150 1.00 110.86 ? 168 GLU B N   1 
ATOM   3651 C CA  . GLU B 2 179 ? 141.889 125.585 126.344 1.00 110.86 ? 168 GLU B CA  1 
ATOM   3652 C C   . GLU B 2 179 ? 140.860 126.187 127.283 1.00 110.86 ? 168 GLU B C   1 
ATOM   3653 O O   . GLU B 2 179 ? 140.845 125.873 128.473 1.00 110.86 ? 168 GLU B O   1 
ATOM   3654 C CB  . GLU B 2 179 ? 142.925 126.640 125.961 1.00 110.86 ? 168 GLU B CB  1 
ATOM   3655 C CG  . GLU B 2 179 ? 143.921 126.173 124.913 1.00 110.86 ? 168 GLU B CG  1 
ATOM   3656 C CD  . GLU B 2 179 ? 144.775 125.012 125.388 1.00 110.86 ? 168 GLU B CD  1 
ATOM   3657 O OE1 . GLU B 2 179 ? 145.387 124.338 124.533 1.00 110.86 ? 168 GLU B OE1 1 
ATOM   3658 O OE2 . GLU B 2 179 ? 144.834 124.771 126.612 1.00 110.86 ? 168 GLU B OE2 1 
ATOM   3659 N N   . GLU B 2 180 ? 139.993 127.046 126.759 1.00 107.77 ? 169 GLU B N   1 
ATOM   3660 C CA  . GLU B 2 180 ? 138.935 127.607 127.586 1.00 107.77 ? 169 GLU B CA  1 
ATOM   3661 C C   . GLU B 2 180 ? 137.999 126.487 127.980 1.00 107.77 ? 169 GLU B C   1 
ATOM   3662 O O   . GLU B 2 180 ? 137.535 126.425 129.119 1.00 107.77 ? 169 GLU B O   1 
ATOM   3663 C CB  . GLU B 2 180 ? 138.169 128.703 126.849 1.00 107.77 ? 169 GLU B CB  1 
ATOM   3664 C CG  . GLU B 2 180 ? 138.996 129.935 126.526 1.00 107.77 ? 169 GLU B CG  1 
ATOM   3665 C CD  . GLU B 2 180 ? 139.879 129.740 125.311 1.00 107.77 ? 169 GLU B CD  1 
ATOM   3666 O OE1 . GLU B 2 180 ? 139.582 128.836 124.506 1.00 107.77 ? 169 GLU B OE1 1 
ATOM   3667 O OE2 . GLU B 2 180 ? 140.862 130.494 125.157 1.00 107.77 ? 169 GLU B OE2 1 
ATOM   3668 N N   . LEU B 2 181 ? 137.721 125.594 127.037 1.00 105.37 ? 170 LEU B N   1 
ATOM   3669 C CA  . LEU B 2 181 ? 136.859 124.459 127.332 1.00 105.37 ? 170 LEU B CA  1 
ATOM   3670 C C   . LEU B 2 181 ? 137.443 123.664 128.484 1.00 105.37 ? 170 LEU B C   1 
ATOM   3671 O O   . LEU B 2 181 ? 136.779 122.795 129.047 1.00 105.37 ? 170 LEU B O   1 
ATOM   3672 C CB  . LEU B 2 181 ? 136.687 123.568 126.102 1.00 105.37 ? 170 LEU B CB  1 
ATOM   3673 C CG  . LEU B 2 181 ? 135.477 123.875 125.217 1.00 105.37 ? 170 LEU B CG  1 
ATOM   3674 C CD1 . LEU B 2 181 ? 134.181 123.566 125.951 1.00 105.37 ? 170 LEU B CD1 1 
ATOM   3675 C CD2 . LEU B 2 181 ? 135.499 125.320 124.746 1.00 105.37 ? 170 LEU B CD2 1 
ATOM   3676 N N   . LEU B 2 182 ? 138.689 123.962 128.837 1.00 111.24 ? 171 LEU B N   1 
ATOM   3677 C CA  . LEU B 2 182 ? 139.332 123.258 129.941 1.00 111.24 ? 171 LEU B CA  1 
ATOM   3678 C C   . LEU B 2 182 ? 139.454 124.141 131.180 1.00 111.24 ? 171 LEU B C   1 
ATOM   3679 O O   . LEU B 2 182 ? 139.532 123.628 132.302 1.00 111.24 ? 171 LEU B O   1 
ATOM   3680 C CB  . LEU B 2 182 ? 140.699 122.726 129.513 1.00 111.24 ? 171 LEU B CB  1 
ATOM   3681 C CG  . LEU B 2 182 ? 140.701 121.306 128.936 1.00 111.24 ? 171 LEU B CG  1 
ATOM   3682 C CD1 . LEU B 2 182 ? 140.274 120.311 130.002 1.00 111.24 ? 171 LEU B CD1 1 
ATOM   3683 C CD2 . LEU B 2 182 ? 139.808 121.178 127.714 1.00 111.24 ? 171 LEU B CD2 1 
ATOM   3684 N N   . LYS B 2 183 ? 139.473 125.465 131.012 1.00 110.84 ? 172 LYS B N   1 
ATOM   3685 C CA  . LYS B 2 183 ? 139.590 126.334 132.180 1.00 110.84 ? 172 LYS B CA  1 
ATOM   3686 C C   . LYS B 2 183 ? 138.271 127.012 132.542 1.00 110.84 ? 172 LYS B C   1 
ATOM   3687 O O   . LYS B 2 183 ? 137.821 126.913 133.687 1.00 110.84 ? 172 LYS B O   1 
ATOM   3688 C CB  . LYS B 2 183 ? 140.687 127.389 131.976 1.00 110.84 ? 172 LYS B CB  1 
ATOM   3689 C CG  . LYS B 2 183 ? 140.576 128.216 130.710 1.00 110.84 ? 172 LYS B CG  1 
ATOM   3690 C CD  . LYS B 2 183 ? 141.654 129.285 130.634 1.00 110.84 ? 172 LYS B CD  1 
ATOM   3691 C CE  . LYS B 2 183 ? 143.043 128.674 130.622 1.00 110.84 ? 172 LYS B CE  1 
ATOM   3692 N NZ  . LYS B 2 183 ? 144.011 129.528 129.883 1.00 110.84 ? 172 LYS B NZ  1 
ATOM   3693 N N   . VAL B 2 184 ? 137.642 127.702 131.588 1.00 108.63 ? 173 VAL B N   1 
ATOM   3694 C CA  . VAL B 2 184 ? 136.481 128.524 131.923 1.00 108.63 ? 173 VAL B CA  1 
ATOM   3695 C C   . VAL B 2 184 ? 135.216 127.676 131.954 1.00 108.63 ? 173 VAL B C   1 
ATOM   3696 O O   . VAL B 2 184 ? 134.197 128.068 132.535 1.00 108.63 ? 173 VAL B O   1 
ATOM   3697 C CB  . VAL B 2 184 ? 136.349 129.705 130.944 1.00 108.63 ? 173 VAL B CB  1 
ATOM   3698 C CG1 . VAL B 2 184 ? 137.669 130.454 130.833 1.00 108.63 ? 173 VAL B CG1 1 
ATOM   3699 C CG2 . VAL B 2 184 ? 135.875 129.233 129.580 1.00 108.63 ? 173 VAL B CG2 1 
ATOM   3700 N N   . ALA B 2 185 ? 135.257 126.500 131.326 1.00 105.93 ? 174 ALA B N   1 
ATOM   3701 C CA  . ALA B 2 185 ? 134.090 125.624 131.343 1.00 105.93 ? 174 ALA B CA  1 
ATOM   3702 C C   . ALA B 2 185 ? 134.141 124.654 132.515 1.00 105.93 ? 174 ALA B C   1 
ATOM   3703 O O   . ALA B 2 185 ? 133.103 124.321 133.098 1.00 105.93 ? 174 ALA B O   1 
ATOM   3704 C CB  . ALA B 2 185 ? 133.983 124.863 130.025 1.00 105.93 ? 174 ALA B CB  1 
ATOM   3705 N N   . GLY B 2 186 ? 135.338 124.185 132.872 1.00 108.88 ? 175 GLY B N   1 
ATOM   3706 C CA  . GLY B 2 186 ? 135.476 123.274 133.994 1.00 108.88 ? 175 GLY B CA  1 
ATOM   3707 C C   . GLY B 2 186 ? 135.297 123.930 135.347 1.00 108.88 ? 175 GLY B C   1 
ATOM   3708 O O   . GLY B 2 186 ? 135.494 123.272 136.374 1.00 108.88 ? 175 GLY B O   1 
ATOM   3709 N N   . SER B 2 187 ? 134.942 125.209 135.374 1.00 108.08 ? 176 SER B N   1 
ATOM   3710 C CA  . SER B 2 187 ? 134.714 125.892 136.637 1.00 108.08 ? 176 SER B CA  1 
ATOM   3711 C C   . SER B 2 187 ? 133.530 125.255 137.361 1.00 108.08 ? 176 SER B C   1 
ATOM   3712 O O   . SER B 2 187 ? 132.642 124.687 136.712 1.00 108.08 ? 176 SER B O   1 
ATOM   3713 C CB  . SER B 2 187 ? 134.453 127.382 136.397 1.00 108.08 ? 176 SER B CB  1 
ATOM   3714 O OG  . SER B 2 187 ? 133.078 127.627 136.163 1.00 108.08 ? 176 SER B OG  1 
ATOM   3715 N N   . PRO B 2 188 ? 133.485 125.319 138.695 1.00 108.51 ? 177 PRO B N   1 
ATOM   3716 C CA  . PRO B 2 188 ? 132.382 124.663 139.422 1.00 108.51 ? 177 PRO B CA  1 
ATOM   3717 C C   . PRO B 2 188 ? 130.998 125.135 139.006 1.00 108.51 ? 177 PRO B C   1 
ATOM   3718 O O   . PRO B 2 188 ? 130.069 124.321 138.919 1.00 108.51 ? 177 PRO B O   1 
ATOM   3719 C CB  . PRO B 2 188 ? 132.692 125.008 140.883 1.00 108.51 ? 177 PRO B CB  1 
ATOM   3720 C CG  . PRO B 2 188 ? 134.173 125.173 140.913 1.00 108.51 ? 177 PRO B CG  1 
ATOM   3721 C CD  . PRO B 2 188 ? 134.523 125.826 139.608 1.00 108.51 ? 177 PRO B CD  1 
ATOM   3722 N N   . GLY B 2 189 ? 130.836 126.431 138.734 1.00 106.00 ? 178 GLY B N   1 
ATOM   3723 C CA  . GLY B 2 189 ? 129.527 126.935 138.349 1.00 106.00 ? 178 GLY B CA  1 
ATOM   3724 C C   . GLY B 2 189 ? 129.013 126.310 137.066 1.00 106.00 ? 178 GLY B C   1 
ATOM   3725 O O   . GLY B 2 189 ? 127.878 125.829 137.004 1.00 106.00 ? 178 GLY B O   1 
ATOM   3726 N N   . TRP B 2 190 ? 129.846 126.305 136.024 1.00 104.33 ? 179 TRP B N   1 
ATOM   3727 C CA  . TRP B 2 190 ? 129.403 125.804 134.727 1.00 104.33 ? 179 TRP B CA  1 
ATOM   3728 C C   . TRP B 2 190 ? 129.154 124.301 134.766 1.00 104.33 ? 179 TRP B C   1 
ATOM   3729 O O   . TRP B 2 190 ? 128.199 123.806 134.157 1.00 104.33 ? 179 TRP B O   1 
ATOM   3730 C CB  . TRP B 2 190 ? 130.426 126.157 133.650 1.00 104.33 ? 179 TRP B CB  1 
ATOM   3731 C CG  . TRP B 2 190 ? 130.117 127.443 132.954 1.00 104.33 ? 179 TRP B CG  1 
ATOM   3732 C CD1 . TRP B 2 190 ? 130.798 128.618 133.065 1.00 104.33 ? 179 TRP B CD1 1 
ATOM   3733 C CD2 . TRP B 2 190 ? 129.038 127.688 132.045 1.00 104.33 ? 179 TRP B CD2 1 
ATOM   3734 N NE1 . TRP B 2 190 ? 130.214 129.580 132.276 1.00 104.33 ? 179 TRP B NE1 1 
ATOM   3735 C CE2 . TRP B 2 190 ? 129.131 129.033 131.640 1.00 104.33 ? 179 TRP B CE2 1 
ATOM   3736 C CE3 . TRP B 2 190 ? 128.006 126.899 131.532 1.00 104.33 ? 179 TRP B CE3 1 
ATOM   3737 C CZ2 . TRP B 2 190 ? 128.232 129.606 130.747 1.00 104.33 ? 179 TRP B CZ2 1 
ATOM   3738 C CZ3 . TRP B 2 190 ? 127.114 127.471 130.646 1.00 104.33 ? 179 TRP B CZ3 1 
ATOM   3739 C CH2 . TRP B 2 190 ? 127.233 128.811 130.263 1.00 104.33 ? 179 TRP B CH2 1 
ATOM   3740 N N   . VAL B 2 191 ? 129.993 123.552 135.486 1.00 101.59 ? 180 VAL B N   1 
ATOM   3741 C CA  . VAL B 2 191 ? 129.799 122.105 135.531 1.00 101.59 ? 180 VAL B CA  1 
ATOM   3742 C C   . VAL B 2 191 ? 128.569 121.765 136.362 1.00 101.59 ? 180 VAL B C   1 
ATOM   3743 O O   . VAL B 2 191 ? 127.824 120.831 136.041 1.00 101.59 ? 180 VAL B O   1 
ATOM   3744 C CB  . VAL B 2 191 ? 131.062 121.392 136.052 1.00 101.59 ? 180 VAL B CB  1 
ATOM   3745 C CG1 . VAL B 2 191 ? 131.413 121.848 137.449 1.00 101.59 ? 180 VAL B CG1 1 
ATOM   3746 C CG2 . VAL B 2 191 ? 130.877 119.882 136.008 1.00 101.59 ? 180 VAL B CG2 1 
ATOM   3747 N N   . ARG B 2 192 ? 128.320 122.527 137.431 1.00 101.19 ? 181 ARG B N   1 
ATOM   3748 C CA  . ARG B 2 192 ? 127.084 122.333 138.177 1.00 101.19 ? 181 ARG B CA  1 
ATOM   3749 C C   . ARG B 2 192 ? 125.868 122.656 137.322 1.00 101.19 ? 181 ARG B C   1 
ATOM   3750 O O   . ARG B 2 192 ? 124.860 121.944 137.386 1.00 101.19 ? 181 ARG B O   1 
ATOM   3751 C CB  . ARG B 2 192 ? 127.089 123.184 139.447 1.00 101.19 ? 181 ARG B CB  1 
ATOM   3752 C CG  . ARG B 2 192 ? 127.919 122.599 140.580 1.00 101.19 ? 181 ARG B CG  1 
ATOM   3753 C CD  . ARG B 2 192 ? 127.184 121.464 141.281 1.00 101.19 ? 181 ARG B CD  1 
ATOM   3754 N NE  . ARG B 2 192 ? 127.445 120.165 140.665 1.00 101.19 ? 181 ARG B NE  1 
ATOM   3755 C CZ  . ARG B 2 192 ? 128.470 119.380 140.979 1.00 101.19 ? 181 ARG B CZ  1 
ATOM   3756 N NH1 . ARG B 2 192 ? 128.627 118.215 140.366 1.00 101.19 ? 181 ARG B NH1 1 
ATOM   3757 N NH2 . ARG B 2 192 ? 129.339 119.759 141.906 1.00 101.19 ? 181 ARG B NH2 1 
ATOM   3758 N N   . THR B 2 193 ? 125.949 123.705 136.503 1.00 98.47  ? 182 THR B N   1 
ATOM   3759 C CA  . THR B 2 193 ? 124.837 124.038 135.618 1.00 98.47  ? 182 THR B CA  1 
ATOM   3760 C C   . THR B 2 193 ? 124.610 122.937 134.590 1.00 98.47  ? 182 THR B C   1 
ATOM   3761 O O   . THR B 2 193 ? 123.467 122.592 134.274 1.00 98.47  ? 182 THR B O   1 
ATOM   3762 C CB  . THR B 2 193 ? 125.100 125.379 134.931 1.00 98.47  ? 182 THR B CB  1 
ATOM   3763 O OG1 . THR B 2 193 ? 125.164 126.417 135.917 1.00 98.47  ? 182 THR B OG1 1 
ATOM   3764 C CG2 . THR B 2 193 ? 123.992 125.704 133.943 1.00 98.47  ? 182 THR B CG2 1 
ATOM   3765 N N   . ARG B 2 194 ? 125.693 122.360 134.066 1.00 94.72  ? 183 ARG B N   1 
ATOM   3766 C CA  . ARG B 2 194 ? 125.555 121.283 133.091 1.00 94.72  ? 183 ARG B CA  1 
ATOM   3767 C C   . ARG B 2 194 ? 124.942 120.039 133.725 1.00 94.72  ? 183 ARG B C   1 
ATOM   3768 O O   . ARG B 2 194 ? 124.073 119.390 133.127 1.00 94.72  ? 183 ARG B O   1 
ATOM   3769 C CB  . ARG B 2 194 ? 126.916 120.965 132.472 1.00 94.72  ? 183 ARG B CB  1 
ATOM   3770 C CG  . ARG B 2 194 ? 126.871 120.051 131.259 1.00 94.72  ? 183 ARG B CG  1 
ATOM   3771 C CD  . ARG B 2 194 ? 127.222 118.622 131.631 1.00 94.72  ? 183 ARG B CD  1 
ATOM   3772 N NE  . ARG B 2 194 ? 128.444 118.555 132.429 1.00 94.72  ? 183 ARG B NE  1 
ATOM   3773 C CZ  . ARG B 2 194 ? 129.652 118.309 131.935 1.00 94.72  ? 183 ARG B CZ  1 
ATOM   3774 N NH1 . ARG B 2 194 ? 130.704 118.270 132.741 1.00 94.72  ? 183 ARG B NH1 1 
ATOM   3775 N NH2 . ARG B 2 194 ? 129.806 118.095 130.637 1.00 94.72  ? 183 ARG B NH2 1 
ATOM   3776 N N   . TRP B 2 195 ? 125.382 119.689 134.935 1.00 92.53  ? 184 TRP B N   1 
ATOM   3777 C CA  . TRP B 2 195 ? 124.793 118.553 135.637 1.00 92.53  ? 184 TRP B CA  1 
ATOM   3778 C C   . TRP B 2 195 ? 123.318 118.800 135.921 1.00 92.53  ? 184 TRP B C   1 
ATOM   3779 O O   . TRP B 2 195 ? 122.485 117.896 135.790 1.00 92.53  ? 184 TRP B O   1 
ATOM   3780 C CB  . TRP B 2 195 ? 125.554 118.281 136.935 1.00 92.53  ? 184 TRP B CB  1 
ATOM   3781 C CG  . TRP B 2 195 ? 126.817 117.500 136.754 1.00 92.53  ? 184 TRP B CG  1 
ATOM   3782 C CD1 . TRP B 2 195 ? 128.047 117.818 137.246 1.00 92.53  ? 184 TRP B CD1 1 
ATOM   3783 C CD2 . TRP B 2 195 ? 126.977 116.265 136.043 1.00 92.53  ? 184 TRP B CD2 1 
ATOM   3784 N NE1 . TRP B 2 195 ? 128.966 116.866 136.881 1.00 92.53  ? 184 TRP B NE1 1 
ATOM   3785 C CE2 . TRP B 2 195 ? 128.334 115.900 136.143 1.00 92.53  ? 184 TRP B CE2 1 
ATOM   3786 C CE3 . TRP B 2 195 ? 126.108 115.433 135.332 1.00 92.53  ? 184 TRP B CE3 1 
ATOM   3787 C CZ2 . TRP B 2 195 ? 128.842 114.743 135.558 1.00 92.53  ? 184 TRP B CZ2 1 
ATOM   3788 C CZ3 . TRP B 2 195 ? 126.615 114.285 134.751 1.00 92.53  ? 184 TRP B CZ3 1 
ATOM   3789 C CH2 . TRP B 2 195 ? 127.968 113.951 134.869 1.00 92.53  ? 184 TRP B CH2 1 
ATOM   3790 N N   . ALA B 2 196 ? 122.976 120.029 136.313 1.00 88.21  ? 185 ALA B N   1 
ATOM   3791 C CA  . ALA B 2 196 ? 121.580 120.365 136.565 1.00 88.21  ? 185 ALA B CA  1 
ATOM   3792 C C   . ALA B 2 196 ? 120.749 120.246 135.297 1.00 88.21  ? 185 ALA B C   1 
ATOM   3793 O O   . ALA B 2 196 ? 119.624 119.738 135.331 1.00 88.21  ? 185 ALA B O   1 
ATOM   3794 C CB  . ALA B 2 196 ? 121.474 121.774 137.147 1.00 88.21  ? 185 ALA B CB  1 
ATOM   3795 N N   . LEU B 2 197 ? 121.284 120.713 134.168 1.00 80.21  ? 186 LEU B N   1 
ATOM   3796 C CA  . LEU B 2 197 ? 120.576 120.575 132.900 1.00 80.21  ? 186 LEU B CA  1 
ATOM   3797 C C   . LEU B 2 197 ? 120.348 119.111 132.552 1.00 80.21  ? 186 LEU B C   1 
ATOM   3798 O O   . LEU B 2 197 ? 119.244 118.726 132.153 1.00 80.21  ? 186 LEU B O   1 
ATOM   3799 C CB  . LEU B 2 197 ? 121.350 121.275 131.783 1.00 80.21  ? 186 LEU B CB  1 
ATOM   3800 C CG  . LEU B 2 197 ? 120.918 122.684 131.374 1.00 80.21  ? 186 LEU B CG  1 
ATOM   3801 C CD1 . LEU B 2 197 ? 119.642 122.633 130.560 1.00 80.21  ? 186 LEU B CD1 1 
ATOM   3802 C CD2 . LEU B 2 197 ? 120.734 123.570 132.590 1.00 80.21  ? 186 LEU B CD2 1 
ATOM   3803 N N   . LEU B 2 198 ? 121.377 118.277 132.701 1.00 74.97  ? 187 LEU B N   1 
ATOM   3804 C CA  . LEU B 2 198 ? 121.214 116.862 132.383 1.00 74.97  ? 187 LEU B CA  1 
ATOM   3805 C C   . LEU B 2 198 ? 120.188 116.205 133.297 1.00 74.97  ? 187 LEU B C   1 
ATOM   3806 O O   . LEU B 2 198 ? 119.358 115.405 132.843 1.00 74.97  ? 187 LEU B O   1 
ATOM   3807 C CB  . LEU B 2 198 ? 122.556 116.140 132.479 1.00 74.97  ? 187 LEU B CB  1 
ATOM   3808 C CG  . LEU B 2 198 ? 122.616 114.720 131.911 1.00 74.97  ? 187 LEU B CG  1 
ATOM   3809 C CD1 . LEU B 2 198 ? 123.951 114.494 131.228 1.00 74.97  ? 187 LEU B CD1 1 
ATOM   3810 C CD2 . LEU B 2 198 ? 122.390 113.673 132.991 1.00 74.97  ? 187 LEU B CD2 1 
ATOM   3811 N N   . LEU B 2 199 ? 120.222 116.529 134.589 1.00 71.49  ? 188 LEU B N   1 
ATOM   3812 C CA  . LEU B 2 199 ? 119.311 115.872 135.516 1.00 71.49  ? 188 LEU B CA  1 
ATOM   3813 C C   . LEU B 2 199 ? 117.884 116.363 135.316 1.00 71.49  ? 188 LEU B C   1 
ATOM   3814 O O   . LEU B 2 199 ? 116.932 115.591 135.462 1.00 71.49  ? 188 LEU B O   1 
ATOM   3815 C CB  . LEU B 2 199 ? 119.768 116.098 136.953 1.00 71.49  ? 188 LEU B CB  1 
ATOM   3816 C CG  . LEU B 2 199 ? 118.999 115.297 138.000 1.00 71.49  ? 188 LEU B CG  1 
ATOM   3817 C CD1 . LEU B 2 199 ? 119.198 113.806 137.760 1.00 71.49  ? 188 LEU B CD1 1 
ATOM   3818 C CD2 . LEU B 2 199 ? 119.443 115.688 139.399 1.00 71.49  ? 188 LEU B CD2 1 
ATOM   3819 N N   . LEU B 2 200 ? 117.715 117.638 134.961 1.00 69.22  ? 189 LEU B N   1 
ATOM   3820 C CA  . LEU B 2 200 ? 116.394 118.134 134.596 1.00 69.22  ? 189 LEU B CA  1 
ATOM   3821 C C   . LEU B 2 200 ? 115.895 117.462 133.325 1.00 69.22  ? 189 LEU B C   1 
ATOM   3822 O O   . LEU B 2 200 ? 114.698 117.187 133.189 1.00 69.22  ? 189 LEU B O   1 
ATOM   3823 C CB  . LEU B 2 200 ? 116.434 119.653 134.431 1.00 69.22  ? 189 LEU B CB  1 
ATOM   3824 C CG  . LEU B 2 200 ? 115.153 120.370 134.002 1.00 69.22  ? 189 LEU B CG  1 
ATOM   3825 C CD1 . LEU B 2 200 ? 114.996 121.659 134.783 1.00 69.22  ? 189 LEU B CD1 1 
ATOM   3826 C CD2 . LEU B 2 200 ? 115.166 120.656 132.510 1.00 69.22  ? 189 LEU B CD2 1 
ATOM   3827 N N   . PHE B 2 201 ? 116.799 117.185 132.384 1.00 59.05  ? 190 PHE B N   1 
ATOM   3828 C CA  . PHE B 2 201 ? 116.413 116.443 131.189 1.00 59.05  ? 190 PHE B CA  1 
ATOM   3829 C C   . PHE B 2 201 ? 115.901 115.059 131.546 1.00 59.05  ? 190 PHE B C   1 
ATOM   3830 O O   . PHE B 2 201 ? 114.864 114.619 131.042 1.00 59.05  ? 190 PHE B O   1 
ATOM   3831 C CB  . PHE B 2 201 ? 117.589 116.326 130.226 1.00 59.05  ? 190 PHE B CB  1 
ATOM   3832 C CG  . PHE B 2 201 ? 117.321 115.415 129.063 1.00 59.05  ? 190 PHE B CG  1 
ATOM   3833 C CD1 . PHE B 2 201 ? 116.529 115.825 128.011 1.00 59.05  ? 190 PHE B CD1 1 
ATOM   3834 C CD2 . PHE B 2 201 ? 117.853 114.138 129.035 1.00 59.05  ? 190 PHE B CD2 1 
ATOM   3835 C CE1 . PHE B 2 201 ? 116.284 114.983 126.947 1.00 59.05  ? 190 PHE B CE1 1 
ATOM   3836 C CE2 . PHE B 2 201 ? 117.610 113.296 127.975 1.00 59.05  ? 190 PHE B CE2 1 
ATOM   3837 C CZ  . PHE B 2 201 ? 116.825 113.718 126.930 1.00 59.05  ? 190 PHE B CZ  1 
ATOM   3838 N N   . TRP B 2 202 ? 116.623 114.347 132.407 1.00 56.36  ? 191 TRP B N   1 
ATOM   3839 C CA  . TRP B 2 202 ? 116.178 112.996 132.726 1.00 56.36  ? 191 TRP B CA  1 
ATOM   3840 C C   . TRP B 2 202 ? 114.954 113.007 133.630 1.00 56.36  ? 191 TRP B C   1 
ATOM   3841 O O   . TRP B 2 202 ? 114.164 112.057 133.607 1.00 56.36  ? 191 TRP B O   1 
ATOM   3842 C CB  . TRP B 2 202 ? 117.318 112.183 133.329 1.00 56.36  ? 191 TRP B CB  1 
ATOM   3843 C CG  . TRP B 2 202 ? 118.104 111.529 132.254 1.00 56.36  ? 191 TRP B CG  1 
ATOM   3844 C CD1 . TRP B 2 202 ? 119.147 112.064 131.566 1.00 56.36  ? 191 TRP B CD1 1 
ATOM   3845 C CD2 . TRP B 2 202 ? 117.871 110.237 131.690 1.00 56.36  ? 191 TRP B CD2 1 
ATOM   3846 N NE1 . TRP B 2 202 ? 119.598 111.175 130.625 1.00 56.36  ? 191 TRP B NE1 1 
ATOM   3847 C CE2 . TRP B 2 202 ? 118.828 110.045 130.680 1.00 56.36  ? 191 TRP B CE2 1 
ATOM   3848 C CE3 . TRP B 2 202 ? 116.955 109.218 131.951 1.00 56.36  ? 191 TRP B CE3 1 
ATOM   3849 C CZ2 . TRP B 2 202 ? 118.895 108.877 129.930 1.00 56.36  ? 191 TRP B CZ2 1 
ATOM   3850 C CZ3 . TRP B 2 202 ? 117.023 108.059 131.205 1.00 56.36  ? 191 TRP B CZ3 1 
ATOM   3851 C CH2 . TRP B 2 202 ? 117.986 107.897 130.208 1.00 56.36  ? 191 TRP B CH2 1 
ATOM   3852 N N   . LEU B 2 203 ? 114.737 114.092 134.374 1.00 59.64  ? 192 LEU B N   1 
ATOM   3853 C CA  . LEU B 2 203 ? 113.473 114.243 135.085 1.00 59.64  ? 192 LEU B CA  1 
ATOM   3854 C C   . LEU B 2 203 ? 112.323 114.448 134.109 1.00 59.64  ? 192 LEU B C   1 
ATOM   3855 O O   . LEU B 2 203 ? 111.274 113.808 134.235 1.00 59.64  ? 192 LEU B O   1 
ATOM   3856 C CB  . LEU B 2 203 ? 113.553 115.406 136.072 1.00 59.64  ? 192 LEU B CB  1 
ATOM   3857 C CG  . LEU B 2 203 ? 113.767 115.043 137.541 1.00 59.64  ? 192 LEU B CG  1 
ATOM   3858 C CD1 . LEU B 2 203 ? 114.973 114.135 137.718 1.00 59.64  ? 192 LEU B CD1 1 
ATOM   3859 C CD2 . LEU B 2 203 ? 113.913 116.301 138.378 1.00 59.64  ? 192 LEU B CD2 1 
ATOM   3860 N N   . GLY B 2 204 ? 112.507 115.321 133.120 1.00 52.21  ? 193 GLY B N   1 
ATOM   3861 C CA  . GLY B 2 204 ? 111.494 115.482 132.094 1.00 52.21  ? 193 GLY B CA  1 
ATOM   3862 C C   . GLY B 2 204 ? 111.249 114.212 131.307 1.00 52.21  ? 193 GLY B C   1 
ATOM   3863 O O   . GLY B 2 204 ? 110.131 113.961 130.856 1.00 52.21  ? 193 GLY B O   1 
ATOM   3864 N N   . TRP B 2 205 ? 112.270 113.370 131.168 1.00 44.53  ? 194 TRP B N   1 
ATOM   3865 C CA  . TRP B 2 205 ? 112.087 112.144 130.400 1.00 44.53  ? 194 TRP B CA  1 
ATOM   3866 C C   . TRP B 2 205 ? 111.373 111.071 131.210 1.00 44.53  ? 194 TRP B C   1 
ATOM   3867 O O   . TRP B 2 205 ? 110.488 110.384 130.686 1.00 44.53  ? 194 TRP B O   1 
ATOM   3868 C CB  . TRP B 2 205 ? 113.426 111.617 129.903 1.00 44.53  ? 194 TRP B CB  1 
ATOM   3869 C CG  . TRP B 2 205 ? 113.258 110.516 128.940 1.00 44.53  ? 194 TRP B CG  1 
ATOM   3870 C CD1 . TRP B 2 205 ? 112.988 110.629 127.618 1.00 44.53  ? 194 TRP B CD1 1 
ATOM   3871 C CD2 . TRP B 2 205 ? 113.320 109.121 129.222 1.00 44.53  ? 194 TRP B CD2 1 
ATOM   3872 N NE1 . TRP B 2 205 ? 112.886 109.390 127.049 1.00 44.53  ? 194 TRP B NE1 1 
ATOM   3873 C CE2 . TRP B 2 205 ? 113.088 108.444 128.016 1.00 44.53  ? 194 TRP B CE2 1 
ATOM   3874 C CE3 . TRP B 2 205 ? 113.555 108.377 130.376 1.00 44.53  ? 194 TRP B CE3 1 
ATOM   3875 C CZ2 . TRP B 2 205 ? 113.086 107.057 127.929 1.00 44.53  ? 194 TRP B CZ2 1 
ATOM   3876 C CZ3 . TRP B 2 205 ? 113.554 107.000 130.288 1.00 44.53  ? 194 TRP B CZ3 1 
ATOM   3877 C CH2 . TRP B 2 205 ? 113.320 106.355 129.075 1.00 44.53  ? 194 TRP B CH2 1 
ATOM   3878 N N   . LEU B 2 206 ? 111.732 110.900 132.483 1.00 49.97  ? 195 LEU B N   1 
ATOM   3879 C CA  . LEU B 2 206 ? 110.919 110.034 133.325 1.00 49.97  ? 195 LEU B CA  1 
ATOM   3880 C C   . LEU B 2 206 ? 109.503 110.575 133.448 1.00 49.97  ? 195 LEU B C   1 
ATOM   3881 O O   . LEU B 2 206 ? 108.557 109.800 133.607 1.00 49.97  ? 195 LEU B O   1 
ATOM   3882 C CB  . LEU B 2 206 ? 111.550 109.861 134.704 1.00 49.97  ? 195 LEU B CB  1 
ATOM   3883 C CG  . LEU B 2 206 ? 112.553 108.713 134.857 1.00 49.97  ? 195 LEU B CG  1 
ATOM   3884 C CD1 . LEU B 2 206 ? 111.881 107.376 134.576 1.00 49.97  ? 195 LEU B CD1 1 
ATOM   3885 C CD2 . LEU B 2 206 ? 113.768 108.901 133.972 1.00 49.97  ? 195 LEU B CD2 1 
ATOM   3886 N N   . GLY B 2 207 ? 109.327 111.891 133.310 1.00 50.29  ? 196 GLY B N   1 
ATOM   3887 C CA  . GLY B 2 207 ? 107.987 112.451 133.316 1.00 50.29  ? 196 GLY B CA  1 
ATOM   3888 C C   . GLY B 2 207 ? 107.211 112.120 132.056 1.00 50.29  ? 196 GLY B C   1 
ATOM   3889 O O   . GLY B 2 207 ? 106.015 111.833 132.113 1.00 50.29  ? 196 GLY B O   1 
ATOM   3890 N N   . MET B 2 208 ? 107.877 112.168 130.901 1.00 50.43  ? 197 MET B N   1 
ATOM   3891 C CA  . MET B 2 208 ? 107.230 111.762 129.657 1.00 50.43  ? 197 MET B CA  1 
ATOM   3892 C C   . MET B 2 208 ? 106.853 110.286 129.696 1.00 50.43  ? 197 MET B C   1 
ATOM   3893 O O   . MET B 2 208 ? 105.769 109.898 129.245 1.00 50.43  ? 197 MET B O   1 
ATOM   3894 C CB  . MET B 2 208 ? 108.141 112.060 128.469 1.00 50.43  ? 197 MET B CB  1 
ATOM   3895 C CG  . MET B 2 208 ? 108.322 113.535 128.204 1.00 50.43  ? 197 MET B CG  1 
ATOM   3896 S SD  . MET B 2 208 ? 109.299 113.861 126.731 1.00 50.43  ? 197 MET B SD  1 
ATOM   3897 C CE  . MET B 2 208 ? 108.491 115.334 126.106 1.00 50.43  ? 197 MET B CE  1 
ATOM   3898 N N   . LEU B 2 209 ? 107.725 109.446 130.257 1.00 48.84  ? 198 LEU B N   1 
ATOM   3899 C CA  . LEU B 2 209 ? 107.369 108.038 130.420 1.00 48.84  ? 198 LEU B CA  1 
ATOM   3900 C C   . LEU B 2 209 ? 106.199 107.858 131.375 1.00 48.84  ? 198 LEU B C   1 
ATOM   3901 O O   . LEU B 2 209 ? 105.302 107.047 131.116 1.00 48.84  ? 198 LEU B O   1 
ATOM   3902 C CB  . LEU B 2 209 ? 108.565 107.225 130.901 1.00 48.84  ? 198 LEU B CB  1 
ATOM   3903 C CG  . LEU B 2 209 ? 109.302 106.479 129.801 1.00 48.84  ? 198 LEU B CG  1 
ATOM   3904 C CD1 . LEU B 2 209 ? 108.402 105.403 129.237 1.00 48.84  ? 198 LEU B CD1 1 
ATOM   3905 C CD2 . LEU B 2 209 ? 109.695 107.432 128.722 1.00 48.84  ? 198 LEU B CD2 1 
ATOM   3906 N N   . ALA B 2 210 ? 106.199 108.579 132.498 1.00 51.69  ? 199 ALA B N   1 
ATOM   3907 C CA  . ALA B 2 210 ? 105.085 108.471 133.432 1.00 51.69  ? 199 ALA B CA  1 
ATOM   3908 C C   . ALA B 2 210 ? 103.786 108.902 132.774 1.00 51.69  ? 199 ALA B C   1 
ATOM   3909 O O   . ALA B 2 210 ? 102.754 108.242 132.935 1.00 51.69  ? 199 ALA B O   1 
ATOM   3910 C CB  . ALA B 2 210 ? 105.358 109.303 134.682 1.00 51.69  ? 199 ALA B CB  1 
ATOM   3911 N N   . GLY B 2 211 ? 103.824 109.997 132.017 1.00 51.25  ? 200 GLY B N   1 
ATOM   3912 C CA  . GLY B 2 211 ? 102.643 110.429 131.292 1.00 51.25  ? 200 GLY B CA  1 
ATOM   3913 C C   . GLY B 2 211 ? 102.149 109.384 130.314 1.00 51.25  ? 200 GLY B C   1 
ATOM   3914 O O   . GLY B 2 211 ? 100.955 109.084 130.265 1.00 51.25  ? 200 GLY B O   1 
ATOM   3915 N N   . ALA B 2 212 ? 103.057 108.816 129.521 1.00 52.17  ? 201 ALA B N   1 
ATOM   3916 C CA  . ALA B 2 212 ? 102.659 107.776 128.581 1.00 52.17  ? 201 ALA B CA  1 
ATOM   3917 C C   . ALA B 2 212 ? 102.011 106.605 129.307 1.00 52.17  ? 201 ALA B C   1 
ATOM   3918 O O   . ALA B 2 212 ? 100.918 106.157 128.939 1.00 52.17  ? 201 ALA B O   1 
ATOM   3919 C CB  . ALA B 2 212 ? 103.867 107.306 127.773 1.00 52.17  ? 201 ALA B CB  1 
ATOM   3920 N N   . VAL B 2 213 ? 102.657 106.115 130.365 1.00 53.74  ? 202 VAL B N   1 
ATOM   3921 C CA  . VAL B 2 213 ? 102.193 104.891 131.007 1.00 53.74  ? 202 VAL B CA  1 
ATOM   3922 C C   . VAL B 2 213 ? 100.893 105.135 131.768 1.00 53.74  ? 202 VAL B C   1 
ATOM   3923 O O   . VAL B 2 213 ? 100.070 104.224 131.918 1.00 53.74  ? 202 VAL B O   1 
ATOM   3924 C CB  . VAL B 2 213 ? 103.298 104.318 131.913 1.00 53.74  ? 202 VAL B CB  1 
ATOM   3925 C CG1 . VAL B 2 213 ? 102.767 103.193 132.784 1.00 53.74  ? 202 VAL B CG1 1 
ATOM   3926 C CG2 . VAL B 2 213 ? 104.457 103.820 131.070 1.00 53.74  ? 202 VAL B CG2 1 
ATOM   3927 N N   . VAL B 2 214 ? 100.657 106.366 132.227 1.00 55.35  ? 203 VAL B N   1 
ATOM   3928 C CA  . VAL B 2 214 ? 99.424  106.628 132.964 1.00 55.35  ? 203 VAL B CA  1 
ATOM   3929 C C   . VAL B 2 214 ? 98.271  106.889 131.999 1.00 55.35  ? 203 VAL B C   1 
ATOM   3930 O O   . VAL B 2 214 ? 97.137  106.457 132.235 1.00 55.35  ? 203 VAL B O   1 
ATOM   3931 C CB  . VAL B 2 214 ? 99.611  107.783 133.968 1.00 55.35  ? 203 VAL B CB  1 
ATOM   3932 C CG1 . VAL B 2 214 ? 99.775  109.122 133.268 1.00 55.35  ? 203 VAL B CG1 1 
ATOM   3933 C CG2 . VAL B 2 214 ? 98.448  107.823 134.943 1.00 55.35  ? 203 VAL B CG2 1 
ATOM   3934 N N   . ILE B 2 215 ? 98.535  107.599 130.898 1.00 55.36  ? 204 ILE B N   1 
ATOM   3935 C CA  . ILE B 2 215 ? 97.476  107.839 129.925 1.00 55.36  ? 204 ILE B CA  1 
ATOM   3936 C C   . ILE B 2 215 ? 97.116  106.555 129.196 1.00 55.36  ? 204 ILE B C   1 
ATOM   3937 O O   . ILE B 2 215 ? 95.994  106.407 128.698 1.00 55.36  ? 204 ILE B O   1 
ATOM   3938 C CB  . ILE B 2 215 ? 97.891  108.963 128.957 1.00 55.36  ? 204 ILE B CB  1 
ATOM   3939 C CG1 . ILE B 2 215 ? 98.142  110.250 129.736 1.00 55.36  ? 204 ILE B CG1 1 
ATOM   3940 C CG2 . ILE B 2 215 ? 96.811  109.225 127.936 1.00 55.36  ? 204 ILE B CG2 1 
ATOM   3941 C CD1 . ILE B 2 215 ? 97.050  110.576 130.730 1.00 55.36  ? 204 ILE B CD1 1 
ATOM   3942 N N   . ILE B 2 216 ? 98.038  105.592 129.145 1.00 57.65  ? 205 ILE B N   1 
ATOM   3943 C CA  . ILE B 2 216 ? 97.708  104.307 128.539 1.00 57.65  ? 205 ILE B CA  1 
ATOM   3944 C C   . ILE B 2 216 ? 96.678  103.568 129.386 1.00 57.65  ? 205 ILE B C   1 
ATOM   3945 O O   . ILE B 2 216 ? 95.821  102.848 128.857 1.00 57.65  ? 205 ILE B O   1 
ATOM   3946 C CB  . ILE B 2 216 ? 98.986  103.477 128.324 1.00 57.65  ? 205 ILE B CB  1 
ATOM   3947 C CG1 . ILE B 2 216 ? 99.666  103.895 127.024 1.00 57.65  ? 205 ILE B CG1 1 
ATOM   3948 C CG2 . ILE B 2 216 ? 98.684  101.991 128.303 1.00 57.65  ? 205 ILE B CG2 1 
ATOM   3949 C CD1 . ILE B 2 216 ? 101.127 103.543 126.974 1.00 57.65  ? 205 ILE B CD1 1 
ATOM   3950 N N   . VAL B 2 217 ? 96.715  103.757 130.709 1.00 59.76  ? 206 VAL B N   1 
ATOM   3951 C CA  . VAL B 2 217 ? 95.689  103.170 131.570 1.00 59.76  ? 206 VAL B CA  1 
ATOM   3952 C C   . VAL B 2 217 ? 94.559  104.139 131.870 1.00 59.76  ? 206 VAL B C   1 
ATOM   3953 O O   . VAL B 2 217 ? 93.723  103.854 132.738 1.00 59.76  ? 206 VAL B O   1 
ATOM   3954 C CB  . VAL B 2 217 ? 96.293  102.652 132.891 1.00 59.76  ? 206 VAL B CB  1 
ATOM   3955 C CG1 . VAL B 2 217 ? 97.494  101.768 132.607 1.00 59.76  ? 206 VAL B CG1 1 
ATOM   3956 C CG2 . VAL B 2 217 ? 96.679  103.803 133.796 1.00 59.76  ? 206 VAL B CG2 1 
ATOM   3957 N N   . ARG B 2 218 ? 94.497  105.270 131.170 1.00 68.22  ? 207 ARG B N   1 
ATOM   3958 C CA  . ARG B 2 218 ? 93.403  106.220 131.324 1.00 68.22  ? 207 ARG B CA  1 
ATOM   3959 C C   . ARG B 2 218 ? 92.342  106.031 130.247 1.00 68.22  ? 207 ARG B C   1 
ATOM   3960 O O   . ARG B 2 218 ? 91.145  106.021 130.548 1.00 68.22  ? 207 ARG B O   1 
ATOM   3961 C CB  . ARG B 2 218 ? 93.936  107.654 131.292 1.00 68.22  ? 207 ARG B CB  1 
ATOM   3962 C CG  . ARG B 2 218 ? 92.865  108.727 131.429 1.00 68.22  ? 207 ARG B CG  1 
ATOM   3963 C CD  . ARG B 2 218 ? 92.122  108.618 132.751 1.00 68.22  ? 207 ARG B CD  1 
ATOM   3964 N NE  . ARG B 2 218 ? 92.982  108.179 133.846 1.00 68.22  ? 207 ARG B NE  1 
ATOM   3965 C CZ  . ARG B 2 218 ? 93.892  108.943 134.441 1.00 68.22  ? 207 ARG B CZ  1 
ATOM   3966 N NH1 . ARG B 2 218 ? 94.070  110.197 134.050 1.00 68.22  ? 207 ARG B NH1 1 
ATOM   3967 N NH2 . ARG B 2 218 ? 94.626  108.450 135.428 1.00 68.22  ? 207 ARG B NH2 1 
ATOM   3968 N N   . ALA B 2 219 ? 92.764  105.899 128.996 1.00 73.69  ? 208 ALA B N   1 
ATOM   3969 C CA  . ALA B 2 219 ? 91.823  105.591 127.935 1.00 73.69  ? 208 ALA B CA  1 
ATOM   3970 C C   . ALA B 2 219 ? 91.193  104.225 128.196 1.00 73.69  ? 208 ALA B C   1 
ATOM   3971 O O   . ALA B 2 219 ? 91.864  103.319 128.706 1.00 73.69  ? 208 ALA B O   1 
ATOM   3972 C CB  . ALA B 2 219 ? 92.520  105.603 126.575 1.00 73.69  ? 208 ALA B CB  1 
ATOM   3973 N N   . PRO B 2 220 ? 89.918  104.041 127.871 1.00 83.31  ? 209 PRO B N   1 
ATOM   3974 C CA  . PRO B 2 220 ? 89.246  102.786 128.214 1.00 83.31  ? 209 PRO B CA  1 
ATOM   3975 C C   . PRO B 2 220 ? 89.743  101.633 127.358 1.00 83.31  ? 209 PRO B C   1 
ATOM   3976 O O   . PRO B 2 220 ? 90.294  101.815 126.271 1.00 83.31  ? 209 PRO B O   1 
ATOM   3977 C CB  . PRO B 2 220 ? 87.772  103.089 127.936 1.00 83.31  ? 209 PRO B CB  1 
ATOM   3978 C CG  . PRO B 2 220 ? 87.810  104.128 126.873 1.00 83.31  ? 209 PRO B CG  1 
ATOM   3979 C CD  . PRO B 2 220 ? 89.031  104.964 127.141 1.00 83.31  ? 209 PRO B CD  1 
ATOM   3980 N N   . ARG B 2 221 ? 89.543  100.426 127.880 1.00 93.47  ? 210 ARG B N   1 
ATOM   3981 C CA  . ARG B 2 221 ? 89.972  99.222  127.185 1.00 93.47  ? 210 ARG B CA  1 
ATOM   3982 C C   . ARG B 2 221 ? 89.261  99.087  125.844 1.00 93.47  ? 210 ARG B C   1 
ATOM   3983 O O   . ARG B 2 221 ? 88.301  99.802  125.544 1.00 93.47  ? 210 ARG B O   1 
ATOM   3984 C CB  . ARG B 2 221 ? 89.705  97.985  128.042 1.00 93.47  ? 210 ARG B CB  1 
ATOM   3985 C CG  . ARG B 2 221 ? 90.482  97.950  129.347 1.00 93.47  ? 210 ARG B CG  1 
ATOM   3986 C CD  . ARG B 2 221 ? 91.972  97.747  129.109 1.00 93.47  ? 210 ARG B CD  1 
ATOM   3987 N NE  . ARG B 2 221 ? 92.262  96.447  128.509 1.00 93.47  ? 210 ARG B NE  1 
ATOM   3988 C CZ  . ARG B 2 221 ? 93.430  96.118  127.969 1.00 93.47  ? 210 ARG B CZ  1 
ATOM   3989 N NH1 . ARG B 2 221 ? 94.425  96.993  127.956 1.00 93.47  ? 210 ARG B NH1 1 
ATOM   3990 N NH2 . ARG B 2 221 ? 93.605  94.914  127.444 1.00 93.47  ? 210 ARG B NH2 1 
ATOM   3991 N N   . CYS B 2 222 ? 89.738  98.149  125.038 1.00 97.68  ? 211 CYS B N   1 
ATOM   3992 C CA  . CYS B 2 222 ? 89.212  97.958  123.698 1.00 97.68  ? 211 CYS B CA  1 
ATOM   3993 C C   . CYS B 2 222 ? 88.330  96.714  123.651 1.00 97.68  ? 211 CYS B C   1 
ATOM   3994 O O   . CYS B 2 222 ? 88.757  95.608  123.988 1.00 97.68  ? 211 CYS B O   1 
ATOM   3995 C CB  . CYS B 2 222 ? 90.357  97.835  122.697 1.00 97.68  ? 211 CYS B CB  1 
ATOM   3996 S SG  . CYS B 2 222 ? 89.994  98.503  121.071 1.00 97.68  ? 211 CYS B SG  1 
ATOM   3997 N N   . ARG B 2 223 ? 87.081  96.912  123.232 1.00 93.61  ? 212 ARG B N   1 
ATOM   3998 C CA  . ARG B 2 223 ? 86.104  95.832  123.239 1.00 93.61  ? 212 ARG B CA  1 
ATOM   3999 C C   . ARG B 2 223 ? 86.554  94.690  122.339 1.00 93.61  ? 212 ARG B C   1 
ATOM   4000 O O   . ARG B 2 223 ? 87.339  94.873  121.406 1.00 93.61  ? 212 ARG B O   1 
ATOM   4001 C CB  . ARG B 2 223 ? 84.734  96.334  122.790 1.00 93.61  ? 212 ARG B CB  1 
ATOM   4002 C CG  . ARG B 2 223 ? 83.794  96.661  123.935 1.00 93.61  ? 212 ARG B CG  1 
ATOM   4003 C CD  . ARG B 2 223 ? 82.354  96.762  123.465 1.00 93.61  ? 212 ARG B CD  1 
ATOM   4004 N NE  . ARG B 2 223 ? 81.760  95.447  123.253 1.00 93.61  ? 212 ARG B NE  1 
ATOM   4005 C CZ  . ARG B 2 223 ? 80.599  95.241  122.642 1.00 93.61  ? 212 ARG B CZ  1 
ATOM   4006 N NH1 . ARG B 2 223 ? 80.135  94.009  122.493 1.00 93.61  ? 212 ARG B NH1 1 
ATOM   4007 N NH2 . ARG B 2 223 ? 79.904  96.268  122.173 1.00 93.61  ? 212 ARG B NH2 1 
ATOM   4008 N N   . GLU B 2 224 ? 86.040  93.499  122.627 1.00 93.12  ? 213 GLU B N   1 
ATOM   4009 C CA  . GLU B 2 224 ? 86.483  92.287  121.947 1.00 93.12  ? 213 GLU B CA  1 
ATOM   4010 C C   . GLU B 2 224 ? 85.640  92.072  120.696 1.00 93.12  ? 213 GLU B C   1 
ATOM   4011 O O   . GLU B 2 224 ? 84.411  92.184  120.735 1.00 93.12  ? 213 GLU B O   1 
ATOM   4012 C CB  . GLU B 2 224 ? 86.398  91.090  122.891 1.00 93.12  ? 213 GLU B CB  1 
ATOM   4013 C CG  . GLU B 2 224 ? 84.993  90.730  123.366 1.00 93.12  ? 213 GLU B CG  1 
ATOM   4014 C CD  . GLU B 2 224 ? 84.476  91.638  124.470 1.00 93.12  ? 213 GLU B CD  1 
ATOM   4015 O OE1 . GLU B 2 224 ? 84.997  92.763  124.625 1.00 93.12  ? 213 GLU B OE1 1 
ATOM   4016 O OE2 . GLU B 2 224 ? 83.541  91.223  125.185 1.00 93.12  ? 213 GLU B OE2 1 
ATOM   4017 N N   . LEU B 2 225 ? 86.299  91.786  119.582 1.00 89.27  ? 214 LEU B N   1 
ATOM   4018 C CA  . LEU B 2 225 ? 85.599  91.453  118.356 1.00 89.27  ? 214 LEU B CA  1 
ATOM   4019 C C   . LEU B 2 225 ? 84.909  90.102  118.518 1.00 89.27  ? 214 LEU B C   1 
ATOM   4020 O O   . LEU B 2 225 ? 85.515  89.169  119.064 1.00 89.27  ? 214 LEU B O   1 
ATOM   4021 C CB  . LEU B 2 225 ? 86.567  91.414  117.179 1.00 89.27  ? 214 LEU B CB  1 
ATOM   4022 C CG  . LEU B 2 225 ? 87.654  92.488  117.153 1.00 89.27  ? 214 LEU B CG  1 
ATOM   4023 C CD1 . LEU B 2 225 ? 88.477  92.363  115.885 1.00 89.27  ? 214 LEU B CD1 1 
ATOM   4024 C CD2 . LEU B 2 225 ? 87.045  93.876  117.257 1.00 89.27  ? 214 LEU B CD2 1 
ATOM   4025 N N   . PRO B 2 226 ? 83.668  89.955  118.075 1.00 92.16  ? 215 PRO B N   1 
ATOM   4026 C CA  . PRO B 2 226 ? 82.955  88.690  118.293 1.00 92.16  ? 215 PRO B CA  1 
ATOM   4027 C C   . PRO B 2 226 ? 83.471  87.552  117.429 1.00 92.16  ? 215 PRO B C   1 
ATOM   4028 O O   . PRO B 2 226 ? 82.928  86.444  117.482 1.00 92.16  ? 215 PRO B O   1 
ATOM   4029 C CB  . PRO B 2 226 ? 81.508  89.045  117.937 1.00 92.16  ? 215 PRO B CB  1 
ATOM   4030 C CG  . PRO B 2 226 ? 81.636  90.159  116.964 1.00 92.16  ? 215 PRO B CG  1 
ATOM   4031 C CD  . PRO B 2 226 ? 82.820  90.962  117.418 1.00 92.16  ? 215 PRO B CD  1 
ATOM   4032 N N   . ALA B 2 227 ? 84.516  87.810  116.640 1.00 99.18  ? 216 ALA B N   1 
ATOM   4033 C CA  . ALA B 2 227 ? 85.136  86.805  115.777 1.00 99.18  ? 216 ALA B CA  1 
ATOM   4034 C C   . ALA B 2 227 ? 84.086  86.124  114.899 1.00 99.18  ? 216 ALA B C   1 
ATOM   4035 O O   . ALA B 2 227 ? 83.850  84.917  114.978 1.00 99.18  ? 216 ALA B O   1 
ATOM   4036 C CB  . ALA B 2 227 ? 85.919  85.779  116.602 1.00 99.18  ? 216 ALA B CB  1 
ATOM   4037 N N   . GLN B 2 228 ? 83.448  86.933  114.059 1.00 99.25  ? 217 GLN B N   1 
ATOM   4038 C CA  . GLN B 2 228 ? 82.338  86.451  113.258 1.00 99.25  ? 217 GLN B CA  1 
ATOM   4039 C C   . GLN B 2 228 ? 82.816  85.418  112.239 1.00 99.25  ? 217 GLN B C   1 
ATOM   4040 O O   . GLN B 2 228 ? 84.011  85.265  111.972 1.00 99.25  ? 217 GLN B O   1 
ATOM   4041 C CB  . GLN B 2 228 ? 81.644  87.614  112.552 1.00 99.25  ? 217 GLN B CB  1 
ATOM   4042 C CG  . GLN B 2 228 ? 82.459  88.249  111.442 1.00 99.25  ? 217 GLN B CG  1 
ATOM   4043 C CD  . GLN B 2 228 ? 83.381  89.335  111.942 1.00 99.25  ? 217 GLN B CD  1 
ATOM   4044 O OE1 . GLN B 2 228 ? 83.641  89.443  113.138 1.00 99.25  ? 217 GLN B OE1 1 
ATOM   4045 N NE2 . GLN B 2 228 ? 83.886  90.149  111.025 1.00 99.25  ? 217 GLN B NE2 1 
ATOM   4046 N N   . LYS B 2 229 ? 81.854  84.705  111.668 1.00 101.65 ? 218 LYS B N   1 
ATOM   4047 C CA  . LYS B 2 229 ? 82.130  83.704  110.648 1.00 101.65 ? 218 LYS B CA  1 
ATOM   4048 C C   . LYS B 2 229 ? 82.315  84.413  109.309 1.00 101.65 ? 218 LYS B C   1 
ATOM   4049 O O   . LYS B 2 229 ? 82.465  85.635  109.244 1.00 101.65 ? 218 LYS B O   1 
ATOM   4050 C CB  . LYS B 2 229 ? 81.012  82.667  110.606 1.00 101.65 ? 218 LYS B CB  1 
ATOM   4051 C CG  . LYS B 2 229 ? 81.025  81.674  111.758 1.00 101.65 ? 218 LYS B CG  1 
ATOM   4052 C CD  . LYS B 2 229 ? 80.445  82.273  113.031 1.00 101.65 ? 218 LYS B CD  1 
ATOM   4053 C CE  . LYS B 2 229 ? 80.463  81.276  114.178 1.00 101.65 ? 218 LYS B CE  1 
ATOM   4054 N NZ  . LYS B 2 229 ? 80.045  81.904  115.462 1.00 101.65 ? 218 LYS B NZ  1 
ATOM   4055 N N   . TRP B 2 230 ? 82.330  83.654  108.214 1.00 97.57  ? 219 TRP B N   1 
ATOM   4056 C CA  . TRP B 2 230 ? 82.401  84.302  106.911 1.00 97.57  ? 219 TRP B CA  1 
ATOM   4057 C C   . TRP B 2 230 ? 81.085  84.975  106.552 1.00 97.57  ? 219 TRP B C   1 
ATOM   4058 O O   . TRP B 2 230 ? 81.090  86.076  105.991 1.00 97.57  ? 219 TRP B O   1 
ATOM   4059 C CB  . TRP B 2 230 ? 82.796  83.299  105.828 1.00 97.57  ? 219 TRP B CB  1 
ATOM   4060 C CG  . TRP B 2 230 ? 81.870  82.138  105.695 1.00 97.57  ? 219 TRP B CG  1 
ATOM   4061 C CD1 . TRP B 2 230 ? 81.959  80.942  106.338 1.00 97.57  ? 219 TRP B CD1 1 
ATOM   4062 C CD2 . TRP B 2 230 ? 80.717  82.056  104.853 1.00 97.57  ? 219 TRP B CD2 1 
ATOM   4063 N NE1 . TRP B 2 230 ? 80.929  80.121  105.954 1.00 97.57  ? 219 TRP B NE1 1 
ATOM   4064 C CE2 . TRP B 2 230 ? 80.152  80.784  105.042 1.00 97.57  ? 219 TRP B CE2 1 
ATOM   4065 C CE3 . TRP B 2 230 ? 80.107  82.936  103.959 1.00 97.57  ? 219 TRP B CE3 1 
ATOM   4066 C CZ2 . TRP B 2 230 ? 79.007  80.371  104.374 1.00 97.57  ? 219 TRP B CZ2 1 
ATOM   4067 C CZ3 . TRP B 2 230 ? 78.970  82.525  103.298 1.00 97.57  ? 219 TRP B CZ3 1 
ATOM   4068 C CH2 . TRP B 2 230 ? 78.433  81.255  103.507 1.00 97.57  ? 219 TRP B CH2 1 
ATOM   4069 N N   . TRP B 2 231 ? 79.954  84.353  106.879 1.00 97.24  ? 220 TRP B N   1 
ATOM   4070 C CA  . TRP B 2 231 ? 78.658  84.857  106.444 1.00 97.24  ? 220 TRP B CA  1 
ATOM   4071 C C   . TRP B 2 231 ? 78.219  86.115  107.179 1.00 97.24  ? 220 TRP B C   1 
ATOM   4072 O O   . TRP B 2 231 ? 77.089  86.566  106.973 1.00 97.24  ? 220 TRP B O   1 
ATOM   4073 C CB  . TRP B 2 231 ? 77.593  83.764  106.575 1.00 97.24  ? 220 TRP B CB  1 
ATOM   4074 C CG  . TRP B 2 231 ? 77.129  83.477  107.965 1.00 97.24  ? 220 TRP B CG  1 
ATOM   4075 C CD1 . TRP B 2 231 ? 76.228  84.193  108.690 1.00 97.24  ? 220 TRP B CD1 1 
ATOM   4076 C CD2 . TRP B 2 231 ? 77.519  82.373  108.789 1.00 97.24  ? 220 TRP B CD2 1 
ATOM   4077 N NE1 . TRP B 2 231 ? 76.043  83.615  109.920 1.00 97.24  ? 220 TRP B NE1 1 
ATOM   4078 C CE2 . TRP B 2 231 ? 76.825  82.495  110.005 1.00 97.24  ? 220 TRP B CE2 1 
ATOM   4079 C CE3 . TRP B 2 231 ? 78.393  81.298  108.618 1.00 97.24  ? 220 TRP B CE3 1 
ATOM   4080 C CZ2 . TRP B 2 231 ? 76.979  81.585  111.046 1.00 97.24  ? 220 TRP B CZ2 1 
ATOM   4081 C CZ3 . TRP B 2 231 ? 78.543  80.395  109.651 1.00 97.24  ? 220 TRP B CZ3 1 
ATOM   4082 C CH2 . TRP B 2 231 ? 77.841  80.544  110.849 1.00 97.24  ? 220 TRP B CH2 1 
ATOM   4083 N N   . HIS B 2 232 ? 79.067  86.687  108.030 1.00 93.21  ? 221 HIS B N   1 
ATOM   4084 C CA  . HIS B 2 232 ? 78.841  88.033  108.537 1.00 93.21  ? 221 HIS B CA  1 
ATOM   4085 C C   . HIS B 2 232 ? 79.622  89.082  107.769 1.00 93.21  ? 221 HIS B C   1 
ATOM   4086 O O   . HIS B 2 232 ? 79.206  90.243  107.726 1.00 93.21  ? 221 HIS B O   1 
ATOM   4087 C CB  . HIS B 2 232 ? 79.226  88.140  110.016 1.00 93.21  ? 221 HIS B CB  1 
ATOM   4088 C CG  . HIS B 2 232 ? 78.420  87.270  110.927 1.00 93.21  ? 221 HIS B CG  1 
ATOM   4089 N ND1 . HIS B 2 232 ? 78.409  87.439  112.294 1.00 93.21  ? 221 HIS B ND1 1 
ATOM   4090 C CD2 . HIS B 2 232 ? 77.609  86.217  110.672 1.00 93.21  ? 221 HIS B CD2 1 
ATOM   4091 C CE1 . HIS B 2 232 ? 77.620  86.532  112.842 1.00 93.21  ? 221 HIS B CE1 1 
ATOM   4092 N NE2 . HIS B 2 232 ? 77.123  85.778  111.879 1.00 93.21  ? 221 HIS B NE2 1 
ATOM   4093 N N   . THR B 2 233 ? 80.732  88.696  107.148 1.00 90.17  ? 222 THR B N   1 
ATOM   4094 C CA  . THR B 2 233 ? 81.668  89.639  106.557 1.00 90.17  ? 222 THR B CA  1 
ATOM   4095 C C   . THR B 2 233 ? 81.159  90.233  105.248 1.00 90.17  ? 222 THR B C   1 
ATOM   4096 O O   . THR B 2 233 ? 81.913  90.921  104.553 1.00 90.17  ? 222 THR B O   1 
ATOM   4097 C CB  . THR B 2 233 ? 83.021  88.952  106.341 1.00 90.17  ? 222 THR B CB  1 
ATOM   4098 O OG1 . THR B 2 233 ? 83.265  88.039  107.418 1.00 90.17  ? 222 THR B OG1 1 
ATOM   4099 C CG2 . THR B 2 233 ? 84.154  89.971  106.325 1.00 90.17  ? 222 THR B CG2 1 
ATOM   4100 N N   . GLY B 2 234 ? 79.900  90.005  104.905 1.00 84.66  ? 223 GLY B N   1 
ATOM   4101 C CA  . GLY B 2 234 ? 79.341  90.577  103.699 1.00 84.66  ? 223 GLY B CA  1 
ATOM   4102 C C   . GLY B 2 234 ? 77.952  90.034  103.460 1.00 84.66  ? 223 GLY B C   1 
ATOM   4103 O O   . GLY B 2 234 ? 77.443  89.205  104.218 1.00 84.66  ? 223 GLY B O   1 
ATOM   4104 N N   . ALA B 2 235 ? 77.348  90.515  102.380 1.00 83.94  ? 224 ALA B N   1 
ATOM   4105 C CA  . ALA B 2 235 ? 76.017  90.064  102.019 1.00 83.94  ? 224 ALA B CA  1 
ATOM   4106 C C   . ALA B 2 235 ? 76.067  88.617  101.538 1.00 83.94  ? 224 ALA B C   1 
ATOM   4107 O O   . ALA B 2 235 ? 77.123  87.985  101.476 1.00 83.94  ? 224 ALA B O   1 
ATOM   4108 C CB  . ALA B 2 235 ? 75.424  90.973  100.947 1.00 83.94  ? 224 ALA B CB  1 
ATOM   4109 N N   . LEU B 2 236 ? 74.904  88.081  101.211 1.00 87.94  ? 225 LEU B N   1 
ATOM   4110 C CA  . LEU B 2 236 ? 74.800  86.823  100.498 1.00 87.94  ? 225 LEU B CA  1 
ATOM   4111 C C   . LEU B 2 236 ? 74.238  87.101  99.112  1.00 87.94  ? 225 LEU B C   1 
ATOM   4112 O O   . LEU B 2 236 ? 74.011  88.255  98.737  1.00 87.94  ? 225 LEU B O   1 
ATOM   4113 C CB  . LEU B 2 236 ? 73.950  85.826  101.281 1.00 87.94  ? 225 LEU B CB  1 
ATOM   4114 C CG  . LEU B 2 236 ? 74.602  85.337  102.569 1.00 87.94  ? 225 LEU B CG  1 
ATOM   4115 C CD1 . LEU B 2 236 ? 73.665  84.423  103.315 1.00 87.94  ? 225 LEU B CD1 1 
ATOM   4116 C CD2 . LEU B 2 236 ? 75.897  84.627  102.258 1.00 87.94  ? 225 LEU B CD2 1 
ATOM   4117 N N   . TYR B 2 237 ? 74.011  86.040  98.342  1.00 100.38 ? 226 TYR B N   1 
ATOM   4118 C CA  . TYR B 2 237 ? 73.564  86.204  96.966  1.00 100.38 ? 226 TYR B CA  1 
ATOM   4119 C C   . TYR B 2 237 ? 73.029  84.865  96.487  1.00 100.38 ? 226 TYR B C   1 
ATOM   4120 O O   . TYR B 2 237 ? 73.636  83.827  96.760  1.00 100.38 ? 226 TYR B O   1 
ATOM   4121 C CB  . TYR B 2 237 ? 74.720  86.677  96.080  1.00 100.38 ? 226 TYR B CB  1 
ATOM   4122 C CG  . TYR B 2 237 ? 74.298  87.196  94.736  1.00 100.38 ? 226 TYR B CG  1 
ATOM   4123 C CD1 . TYR B 2 237 ? 73.849  88.492  94.584  1.00 100.38 ? 226 TYR B CD1 1 
ATOM   4124 C CD2 . TYR B 2 237 ? 74.330  86.384  93.615  1.00 100.38 ? 226 TYR B CD2 1 
ATOM   4125 C CE1 . TYR B 2 237 ? 73.458  88.978  93.358  1.00 100.38 ? 226 TYR B CE1 1 
ATOM   4126 C CE2 . TYR B 2 237 ? 73.926  86.859  92.383  1.00 100.38 ? 226 TYR B CE2 1 
ATOM   4127 C CZ  . TYR B 2 237 ? 73.498  88.164  92.261  1.00 100.38 ? 226 TYR B CZ  1 
ATOM   4128 O OH  . TYR B 2 237 ? 73.103  88.643  91.038  1.00 100.38 ? 226 TYR B OH  1 
ATOM   4129 N N   . ARG B 2 238 ? 71.900  84.884  95.787  1.00 101.98 ? 227 ARG B N   1 
ATOM   4130 C CA  . ARG B 2 238 ? 71.253  83.662  95.325  1.00 101.98 ? 227 ARG B CA  1 
ATOM   4131 C C   . ARG B 2 238 ? 71.354  83.527  93.817  1.00 101.98 ? 227 ARG B C   1 
ATOM   4132 O O   . ARG B 2 238 ? 71.350  84.526  93.096  1.00 101.98 ? 227 ARG B O   1 
ATOM   4133 C CB  . ARG B 2 238 ? 69.779  83.612  95.724  1.00 101.98 ? 227 ARG B CB  1 
ATOM   4134 C CG  . ARG B 2 238 ? 69.538  83.048  97.097  1.00 101.98 ? 227 ARG B CG  1 
ATOM   4135 C CD  . ARG B 2 238 ? 69.684  84.107  98.150  1.00 101.98 ? 227 ARG B CD  1 
ATOM   4136 N NE  . ARG B 2 238 ? 68.703  85.173  97.971  1.00 101.98 ? 227 ARG B NE  1 
ATOM   4137 C CZ  . ARG B 2 238 ? 67.478  85.148  98.483  1.00 101.98 ? 227 ARG B CZ  1 
ATOM   4138 N NH1 . ARG B 2 238 ? 67.087  84.121  99.221  1.00 101.98 ? 227 ARG B NH1 1 
ATOM   4139 N NH2 . ARG B 2 238 ? 66.650  86.157  98.267  1.00 101.98 ? 227 ARG B NH2 1 
ATOM   4140 N N   . ILE B 2 239 ? 71.455  82.288  93.356  1.00 102.84 ? 228 ILE B N   1 
ATOM   4141 C CA  . ILE B 2 239 ? 71.256  81.936  91.959  1.00 102.84 ? 228 ILE B CA  1 
ATOM   4142 C C   . ILE B 2 239 ? 70.051  81.012  91.922  1.00 102.84 ? 228 ILE B C   1 
ATOM   4143 O O   . ILE B 2 239 ? 70.189  79.795  92.081  1.00 102.84 ? 228 ILE B O   1 
ATOM   4144 C CB  . ILE B 2 239 ? 72.493  81.258  91.360  1.00 102.84 ? 228 ILE B CB  1 
ATOM   4145 C CG1 . ILE B 2 239 ? 73.769  82.011  91.743  1.00 102.84 ? 228 ILE B CG1 1 
ATOM   4146 C CG2 . ILE B 2 239 ? 72.356  81.131  89.852  1.00 102.84 ? 228 ILE B CG2 1 
ATOM   4147 C CD1 . ILE B 2 239 ? 73.795  83.454  91.328  1.00 102.84 ? 228 ILE B CD1 1 
ATOM   4148 N N   . GLY B 2 240 ? 68.865  81.590  91.723  1.00 113.32 ? 229 GLY B N   1 
ATOM   4149 C CA  . GLY B 2 240 ? 67.649  80.791  91.750  1.00 113.32 ? 229 GLY B CA  1 
ATOM   4150 C C   . GLY B 2 240 ? 67.642  79.712  90.687  1.00 113.32 ? 229 GLY B C   1 
ATOM   4151 O O   . GLY B 2 240 ? 67.090  78.627  90.885  1.00 113.32 ? 229 GLY B O   1 
ATOM   4152 N N   . ASP B 2 241 ? 68.256  79.998  89.543  1.00 124.68 ? 230 ASP B N   1 
ATOM   4153 C CA  . ASP B 2 241 ? 68.423  79.033  88.468  1.00 124.68 ? 230 ASP B CA  1 
ATOM   4154 C C   . ASP B 2 241 ? 69.692  79.384  87.713  1.00 124.68 ? 230 ASP B C   1 
ATOM   4155 O O   . ASP B 2 241 ? 69.860  80.528  87.280  1.00 124.68 ? 230 ASP B O   1 
ATOM   4156 C CB  . ASP B 2 241 ? 67.221  79.031  87.521  1.00 124.68 ? 230 ASP B CB  1 
ATOM   4157 C CG  . ASP B 2 241 ? 67.460  78.192  86.289  1.00 124.68 ? 230 ASP B CG  1 
ATOM   4158 O OD1 . ASP B 2 241 ? 67.903  77.033  86.438  1.00 124.68 ? 230 ASP B OD1 1 
ATOM   4159 O OD2 . ASP B 2 241 ? 67.208  78.693  85.174  1.00 124.68 ? 230 ASP B OD2 1 
ATOM   4160 N N   . LEU B 2 242 ? 70.587  78.405  87.573  1.00 131.72 ? 231 LEU B N   1 
ATOM   4161 C CA  . LEU B 2 242 ? 71.857  78.648  86.898  1.00 131.72 ? 231 LEU B CA  1 
ATOM   4162 C C   . LEU B 2 242 ? 71.651  79.145  85.473  1.00 131.72 ? 231 LEU B C   1 
ATOM   4163 O O   . LEU B 2 242 ? 72.329  80.083  85.038  1.00 131.72 ? 231 LEU B O   1 
ATOM   4164 C CB  . LEU B 2 242 ? 72.694  77.371  86.894  1.00 131.72 ? 231 LEU B CB  1 
ATOM   4165 C CG  . LEU B 2 242 ? 73.193  76.871  88.249  1.00 131.72 ? 231 LEU B CG  1 
ATOM   4166 C CD1 . LEU B 2 242 ? 73.385  75.365  88.210  1.00 131.72 ? 231 LEU B CD1 1 
ATOM   4167 C CD2 . LEU B 2 242 ? 74.484  77.567  88.628  1.00 131.72 ? 231 LEU B CD2 1 
ATOM   4168 N N   . GLN B 2 243 ? 70.723  78.535  84.737  1.00 136.98 ? 232 GLN B N   1 
ATOM   4169 C CA  . GLN B 2 243 ? 70.506  78.875  83.338  1.00 136.98 ? 232 GLN B CA  1 
ATOM   4170 C C   . GLN B 2 243 ? 69.997  80.295  83.146  1.00 136.98 ? 232 GLN B C   1 
ATOM   4171 O O   . GLN B 2 243 ? 70.430  80.978  82.210  1.00 136.98 ? 232 GLN B O   1 
ATOM   4172 C CB  . GLN B 2 243 ? 69.522  77.888  82.703  1.00 136.98 ? 232 GLN B CB  1 
ATOM   4173 C CG  . GLN B 2 243 ? 69.387  78.022  81.195  1.00 136.98 ? 232 GLN B CG  1 
ATOM   4174 C CD  . GLN B 2 243 ? 70.280  77.055  80.442  1.00 136.98 ? 232 GLN B CD  1 
ATOM   4175 O OE1 . GLN B 2 243 ? 70.804  76.102  81.017  1.00 136.98 ? 232 GLN B OE1 1 
ATOM   4176 N NE2 . GLN B 2 243 ? 70.457  77.297  79.148  1.00 136.98 ? 232 GLN B NE2 1 
ATOM   4177 N N   . ALA B 2 244 ? 69.099  80.761  84.009  1.00 130.31 ? 233 ALA B N   1 
ATOM   4178 C CA  . ALA B 2 244 ? 68.537  82.096  83.867  1.00 130.31 ? 233 ALA B CA  1 
ATOM   4179 C C   . ALA B 2 244 ? 69.460  83.192  84.382  1.00 130.31 ? 233 ALA B C   1 
ATOM   4180 O O   . ALA B 2 244 ? 69.098  84.370  84.298  1.00 130.31 ? 233 ALA B O   1 
ATOM   4181 C CB  . ALA B 2 244 ? 67.190  82.180  84.586  1.00 130.31 ? 233 ALA B CB  1 
ATOM   4182 N N   . PHE B 2 245 ? 70.635  82.845  84.910  1.00 125.85 ? 234 PHE B N   1 
ATOM   4183 C CA  . PHE B 2 245 ? 71.556  83.875  85.373  1.00 125.85 ? 234 PHE B CA  1 
ATOM   4184 C C   . PHE B 2 245 ? 72.346  84.475  84.216  1.00 125.85 ? 234 PHE B C   1 
ATOM   4185 O O   . PHE B 2 245 ? 72.256  85.678  83.952  1.00 125.85 ? 234 PHE B O   1 
ATOM   4186 C CB  . PHE B 2 245 ? 72.502  83.307  86.429  1.00 125.85 ? 234 PHE B CB  1 
ATOM   4187 C CG  . PHE B 2 245 ? 73.303  84.355  87.140  1.00 125.85 ? 234 PHE B CG  1 
ATOM   4188 C CD1 . PHE B 2 245 ? 72.687  85.470  87.676  1.00 125.85 ? 234 PHE B CD1 1 
ATOM   4189 C CD2 . PHE B 2 245 ? 74.673  84.231  87.266  1.00 125.85 ? 234 PHE B CD2 1 
ATOM   4190 C CE1 . PHE B 2 245 ? 73.421  86.438  88.330  1.00 125.85 ? 234 PHE B CE1 1 
ATOM   4191 C CE2 . PHE B 2 245 ? 75.413  85.198  87.918  1.00 125.85 ? 234 PHE B CE2 1 
ATOM   4192 C CZ  . PHE B 2 245 ? 74.785  86.303  88.449  1.00 125.85 ? 234 PHE B CZ  1 
ATOM   4193 N N   . GLN B 2 246 ? 73.124  83.656  83.509  1.00 137.44 ? 235 GLN B N   1 
ATOM   4194 C CA  . GLN B 2 246 ? 73.898  84.156  82.377  1.00 137.44 ? 235 GLN B CA  1 
ATOM   4195 C C   . GLN B 2 246 ? 73.098  84.081  81.078  1.00 137.44 ? 235 GLN B C   1 
ATOM   4196 O O   . GLN B 2 246 ? 73.124  85.017  80.273  1.00 137.44 ? 235 GLN B O   1 
ATOM   4197 C CB  . GLN B 2 246 ? 75.227  83.398  82.259  1.00 137.44 ? 235 GLN B CB  1 
ATOM   4198 C CG  . GLN B 2 246 ? 75.107  81.894  82.100  1.00 137.44 ? 235 GLN B CG  1 
ATOM   4199 C CD  . GLN B 2 246 ? 75.028  81.179  83.431  1.00 137.44 ? 235 GLN B CD  1 
ATOM   4200 O OE1 . GLN B 2 246 ? 74.555  81.736  84.421  1.00 137.44 ? 235 GLN B OE1 1 
ATOM   4201 N NE2 . GLN B 2 246 ? 75.506  79.942  83.467  1.00 137.44 ? 235 GLN B NE2 1 
ATOM   4202 N N   . GLY B 2 247 ? 72.388  82.989  80.865  1.00 142.45 ? 236 GLY B N   1 
ATOM   4203 C CA  . GLY B 2 247 ? 71.522  82.881  79.710  1.00 142.45 ? 236 GLY B CA  1 
ATOM   4204 C C   . GLY B 2 247 ? 71.550  81.470  79.146  1.00 142.45 ? 236 GLY B C   1 
ATOM   4205 O O   . GLY B 2 247 ? 72.000  80.535  79.805  1.00 142.45 ? 236 GLY B O   1 
ATOM   4206 N N   . HIS B 2 248 ? 71.059  81.358  77.915  1.00 147.83 ? 237 HIS B N   1 
ATOM   4207 C CA  . HIS B 2 248 ? 70.991  80.076  77.230  1.00 147.83 ? 237 HIS B CA  1 
ATOM   4208 C C   . HIS B 2 248 ? 72.388  79.549  76.923  1.00 147.83 ? 237 HIS B C   1 
ATOM   4209 O O   . HIS B 2 248 ? 73.367  80.298  76.880  1.00 147.83 ? 237 HIS B O   1 
ATOM   4210 C CB  . HIS B 2 248 ? 70.197  80.215  75.934  1.00 147.83 ? 237 HIS B CB  1 
ATOM   4211 C CG  . HIS B 2 248 ? 70.529  81.451  75.158  1.00 147.83 ? 237 HIS B CG  1 
ATOM   4212 N ND1 . HIS B 2 248 ? 69.818  82.625  75.287  1.00 147.83 ? 237 HIS B ND1 1 
ATOM   4213 C CD2 . HIS B 2 248 ? 71.504  81.699  74.251  1.00 147.83 ? 237 HIS B CD2 1 
ATOM   4214 C CE1 . HIS B 2 248 ? 70.338  83.541  74.490  1.00 147.83 ? 237 HIS B CE1 1 
ATOM   4215 N NE2 . HIS B 2 248 ? 71.361  83.005  73.850  1.00 147.83 ? 237 HIS B NE2 1 
ATOM   4216 N N   . GLY B 2 249 ? 72.471  78.243  76.710  1.00 145.81 ? 238 GLY B N   1 
ATOM   4217 C CA  . GLY B 2 249 ? 73.733  77.615  76.319  1.00 145.81 ? 238 GLY B CA  1 
ATOM   4218 C C   . GLY B 2 249 ? 74.776  77.520  77.404  1.00 145.81 ? 238 GLY B C   1 
ATOM   4219 O O   . GLY B 2 249 ? 75.232  76.421  77.732  1.00 145.81 ? 238 GLY B O   1 
ATOM   4220 N N   . ALA B 2 250 ? 75.172  78.658  77.978  1.00 146.37 ? 239 ALA B N   1 
ATOM   4221 C CA  . ALA B 2 250 ? 76.158  78.697  79.050  1.00 146.37 ? 239 ALA B CA  1 
ATOM   4222 C C   . ALA B 2 250 ? 75.528  78.559  80.431  1.00 146.37 ? 239 ALA B C   1 
ATOM   4223 O O   . ALA B 2 250 ? 76.151  78.936  81.432  1.00 146.37 ? 239 ALA B O   1 
ATOM   4224 C CB  . ALA B 2 250 ? 76.976  79.986  78.964  1.00 146.37 ? 239 ALA B CB  1 
ATOM   4225 N N   . GLY B 2 251 ? 74.314  78.020  80.513  1.00 143.01 ? 240 GLY B N   1 
ATOM   4226 C CA  . GLY B 2 251 ? 73.653  77.830  81.789  1.00 143.01 ? 240 GLY B CA  1 
ATOM   4227 C C   . GLY B 2 251 ? 74.206  76.660  82.574  1.00 143.01 ? 240 GLY B C   1 
ATOM   4228 O O   . GLY B 2 251 ? 73.452  75.812  83.060  1.00 143.01 ? 240 GLY B O   1 
ATOM   4229 N N   . ASN B 2 252 ? 75.529  76.606  82.704  1.00 143.25 ? 241 ASN B N   1 
ATOM   4230 C CA  . ASN B 2 252 ? 76.213  75.519  83.383  1.00 143.25 ? 241 ASN B CA  1 
ATOM   4231 C C   . ASN B 2 252 ? 77.161  76.090  84.428  1.00 143.25 ? 241 ASN B C   1 
ATOM   4232 O O   . ASN B 2 252 ? 77.508  77.274  84.403  1.00 143.25 ? 241 ASN B O   1 
ATOM   4233 C CB  . ASN B 2 252 ? 76.981  74.637  82.388  1.00 143.25 ? 241 ASN B CB  1 
ATOM   4234 C CG  . ASN B 2 252 ? 78.060  75.399  81.647  1.00 143.25 ? 241 ASN B CG  1 
ATOM   4235 O OD1 . ASN B 2 252 ? 79.176  75.552  82.140  1.00 143.25 ? 241 ASN B OD1 1 
ATOM   4236 N ND2 . ASN B 2 252 ? 77.732  75.880  80.454  1.00 143.25 ? 241 ASN B ND2 1 
ATOM   4237 N N   . LEU B 2 253 ? 77.569  75.225  85.359  1.00 142.13 ? 242 LEU B N   1 
ATOM   4238 C CA  . LEU B 2 253 ? 78.480  75.643  86.421  1.00 142.13 ? 242 LEU B CA  1 
ATOM   4239 C C   . LEU B 2 253 ? 79.791  76.169  85.850  1.00 142.13 ? 242 LEU B C   1 
ATOM   4240 O O   . LEU B 2 253 ? 80.291  77.219  86.272  1.00 142.13 ? 242 LEU B O   1 
ATOM   4241 C CB  . LEU B 2 253 ? 78.739  74.482  87.384  1.00 142.13 ? 242 LEU B CB  1 
ATOM   4242 C CG  . LEU B 2 253 ? 77.548  73.897  88.150  1.00 142.13 ? 242 LEU B CG  1 
ATOM   4243 C CD1 . LEU B 2 253 ? 76.830  72.823  87.350  1.00 142.13 ? 242 LEU B CD1 1 
ATOM   4244 C CD2 . LEU B 2 253 ? 78.000  73.350  89.491  1.00 142.13 ? 242 LEU B CD2 1 
ATOM   4245 N N   . ALA B 2 254 ? 80.372  75.441  84.893  1.00 139.62 ? 243 ALA B N   1 
ATOM   4246 C CA  . ALA B 2 254 ? 81.614  75.890  84.275  1.00 139.62 ? 243 ALA B CA  1 
ATOM   4247 C C   . ALA B 2 254 ? 81.434  77.223  83.562  1.00 139.62 ? 243 ALA B C   1 
ATOM   4248 O O   . ALA B 2 254 ? 82.352  78.051  83.553  1.00 139.62 ? 243 ALA B O   1 
ATOM   4249 C CB  . ALA B 2 254 ? 82.132  74.829  83.303  1.00 139.62 ? 243 ALA B CB  1 
ATOM   4250 N N   . GLY B 2 255 ? 80.268  77.448  82.955  1.00 138.94 ? 244 GLY B N   1 
ATOM   4251 C CA  . GLY B 2 255 ? 79.998  78.747  82.361  1.00 138.94 ? 244 GLY B CA  1 
ATOM   4252 C C   . GLY B 2 255 ? 79.896  79.847  83.399  1.00 138.94 ? 244 GLY B C   1 
ATOM   4253 O O   . GLY B 2 255 ? 80.444  80.938  83.217  1.00 138.94 ? 244 GLY B O   1 
ATOM   4254 N N   . LEU B 2 256 ? 79.194  79.577  84.502  1.00 132.27 ? 245 LEU B N   1 
ATOM   4255 C CA  . LEU B 2 256 ? 79.092  80.548  85.585  1.00 132.27 ? 245 LEU B CA  1 
ATOM   4256 C C   . LEU B 2 256 ? 80.444  80.841  86.219  1.00 132.27 ? 245 LEU B C   1 
ATOM   4257 O O   . LEU B 2 256 ? 80.631  81.928  86.778  1.00 132.27 ? 245 LEU B O   1 
ATOM   4258 C CB  . LEU B 2 256 ? 78.101  80.044  86.639  1.00 132.27 ? 245 LEU B CB  1 
ATOM   4259 C CG  . LEU B 2 256 ? 77.670  80.985  87.768  1.00 132.27 ? 245 LEU B CG  1 
ATOM   4260 C CD1 . LEU B 2 256 ? 76.243  80.680  88.170  1.00 132.27 ? 245 LEU B CD1 1 
ATOM   4261 C CD2 . LEU B 2 256 ? 78.579  80.854  88.977  1.00 132.27 ? 245 LEU B CD2 1 
ATOM   4262 N N   . LYS B 2 257 ? 81.390  79.901  86.134  1.00 131.73 ? 246 LYS B N   1 
ATOM   4263 C CA  . LYS B 2 257 ? 82.702  80.067  86.754  1.00 131.73 ? 246 LYS B CA  1 
ATOM   4264 C C   . LYS B 2 257 ? 83.397  81.354  86.328  1.00 131.73 ? 246 LYS B C   1 
ATOM   4265 O O   . LYS B 2 257 ? 84.329  81.799  87.007  1.00 131.73 ? 246 LYS B O   1 
ATOM   4266 C CB  . LYS B 2 257 ? 83.580  78.859  86.415  1.00 131.73 ? 246 LYS B CB  1 
ATOM   4267 C CG  . LYS B 2 257 ? 84.857  78.742  87.231  1.00 131.73 ? 246 LYS B CG  1 
ATOM   4268 C CD  . LYS B 2 257 ? 85.926  77.965  86.476  1.00 131.73 ? 246 LYS B CD  1 
ATOM   4269 C CE  . LYS B 2 257 ? 85.337  76.769  85.743  1.00 131.73 ? 246 LYS B CE  1 
ATOM   4270 N NZ  . LYS B 2 257 ? 86.323  76.138  84.824  1.00 131.73 ? 246 LYS B NZ  1 
ATOM   4271 N N   . GLY B 2 258 ? 82.966  81.967  85.231  1.00 128.21 ? 247 GLY B N   1 
ATOM   4272 C CA  . GLY B 2 258 ? 83.533  83.230  84.808  1.00 128.21 ? 247 GLY B CA  1 
ATOM   4273 C C   . GLY B 2 258 ? 82.926  84.412  85.535  1.00 128.21 ? 247 GLY B C   1 
ATOM   4274 O O   . GLY B 2 258 ? 83.597  85.422  85.762  1.00 128.21 ? 247 GLY B O   1 
ATOM   4275 N N   . ARG B 2 259 ? 81.653  84.293  85.911  1.00 124.34 ? 248 ARG B N   1 
ATOM   4276 C CA  . ARG B 2 259 ? 80.927  85.379  86.559  1.00 124.34 ? 248 ARG B CA  1 
ATOM   4277 C C   . ARG B 2 259 ? 81.416  85.668  87.972  1.00 124.34 ? 248 ARG B C   1 
ATOM   4278 O O   . ARG B 2 259 ? 80.890  86.585  88.616  1.00 124.34 ? 248 ARG B O   1 
ATOM   4279 C CB  . ARG B 2 259 ? 79.431  85.062  86.586  1.00 124.34 ? 248 ARG B CB  1 
ATOM   4280 C CG  . ARG B 2 259 ? 78.859  84.675  85.233  1.00 124.34 ? 248 ARG B CG  1 
ATOM   4281 C CD  . ARG B 2 259 ? 78.982  85.813  84.235  1.00 124.34 ? 248 ARG B CD  1 
ATOM   4282 N NE  . ARG B 2 259 ? 78.395  85.469  82.943  1.00 124.34 ? 248 ARG B NE  1 
ATOM   4283 C CZ  . ARG B 2 259 ? 78.679  86.092  81.805  1.00 124.34 ? 248 ARG B CZ  1 
ATOM   4284 N NH1 . ARG B 2 259 ? 79.543  87.097  81.796  1.00 124.34 ? 248 ARG B NH1 1 
ATOM   4285 N NH2 . ARG B 2 259 ? 78.099  85.712  80.675  1.00 124.34 ? 248 ARG B NH2 1 
ATOM   4286 N N   . LEU B 2 260 ? 82.382  84.905  88.478  1.00 120.74 ? 249 LEU B N   1 
ATOM   4287 C CA  . LEU B 2 260 ? 82.948  85.182  89.789  1.00 120.74 ? 249 LEU B CA  1 
ATOM   4288 C C   . LEU B 2 260 ? 83.908  86.360  89.772  1.00 120.74 ? 249 LEU B C   1 
ATOM   4289 O O   . LEU B 2 260 ? 84.369  86.777  90.839  1.00 120.74 ? 249 LEU B O   1 
ATOM   4290 C CB  . LEU B 2 260 ? 83.654  83.940  90.335  1.00 120.74 ? 249 LEU B CB  1 
ATOM   4291 C CG  . LEU B 2 260 ? 82.791  82.902  91.061  1.00 120.74 ? 249 LEU B CG  1 
ATOM   4292 C CD1 . LEU B 2 260 ? 81.567  82.485  90.262  1.00 120.74 ? 249 LEU B CD1 1 
ATOM   4293 C CD2 . LEU B 2 260 ? 83.627  81.686  91.394  1.00 120.74 ? 249 LEU B CD2 1 
ATOM   4294 N N   . ASP B 2 261 ? 84.225  86.895  88.593  1.00 117.38 ? 250 ASP B N   1 
ATOM   4295 C CA  . ASP B 2 261 ? 84.852  88.205  88.507  1.00 117.38 ? 250 ASP B CA  1 
ATOM   4296 C C   . ASP B 2 261 ? 83.833  89.324  88.640  1.00 117.38 ? 250 ASP B C   1 
ATOM   4297 O O   . ASP B 2 261 ? 84.170  90.402  89.140  1.00 117.38 ? 250 ASP B O   1 
ATOM   4298 C CB  . ASP B 2 261 ? 85.605  88.350  87.182  1.00 117.38 ? 250 ASP B CB  1 
ATOM   4299 C CG  . ASP B 2 261 ? 87.092  88.102  87.326  1.00 117.38 ? 250 ASP B CG  1 
ATOM   4300 O OD1 . ASP B 2 261 ? 87.522  87.681  88.420  1.00 117.38 ? 250 ASP B OD1 1 
ATOM   4301 O OD2 . ASP B 2 261 ? 87.832  88.330  86.346  1.00 117.38 ? 250 ASP B OD2 1 
ATOM   4302 N N   . TYR B 2 262 ? 82.596  89.084  88.204  1.00 115.31 ? 251 TYR B N   1 
ATOM   4303 C CA  . TYR B 2 262 ? 81.525  90.059  88.359  1.00 115.31 ? 251 TYR B CA  1 
ATOM   4304 C C   . TYR B 2 262 ? 81.025  90.100  89.795  1.00 115.31 ? 251 TYR B C   1 
ATOM   4305 O O   . TYR B 2 262 ? 80.895  91.178  90.384  1.00 115.31 ? 251 TYR B O   1 
ATOM   4306 C CB  . TYR B 2 262 ? 80.378  89.722  87.406  1.00 115.31 ? 251 TYR B CB  1 
ATOM   4307 C CG  . TYR B 2 262 ? 79.093  90.473  87.677  1.00 115.31 ? 251 TYR B CG  1 
ATOM   4308 C CD1 . TYR B 2 262 ? 79.094  91.846  87.892  1.00 115.31 ? 251 TYR B CD1 1 
ATOM   4309 C CD2 . TYR B 2 262 ? 77.879  89.804  87.724  1.00 115.31 ? 251 TYR B CD2 1 
ATOM   4310 C CE1 . TYR B 2 262 ? 77.922  92.527  88.139  1.00 115.31 ? 251 TYR B CE1 1 
ATOM   4311 C CE2 . TYR B 2 262 ? 76.704  90.477  87.967  1.00 115.31 ? 251 TYR B CE2 1 
ATOM   4312 C CZ  . TYR B 2 262 ? 76.731  91.836  88.175  1.00 115.31 ? 251 TYR B CZ  1 
ATOM   4313 O OH  . TYR B 2 262 ? 75.558  92.507  88.421  1.00 115.31 ? 251 TYR B OH  1 
ATOM   4314 N N   . LEU B 2 263 ? 80.722  88.932  90.362  1.00 106.17 ? 252 LEU B N   1 
ATOM   4315 C CA  . LEU B 2 263 ? 80.144  88.886  91.703  1.00 106.17 ? 252 LEU B CA  1 
ATOM   4316 C C   . LEU B 2 263 ? 81.042  89.577  92.719  1.00 106.17 ? 252 LEU B C   1 
ATOM   4317 O O   . LEU B 2 263 ? 80.561  90.354  93.551  1.00 106.17 ? 252 LEU B O   1 
ATOM   4318 C CB  . LEU B 2 263 ? 79.873  87.442  92.118  1.00 106.17 ? 252 LEU B CB  1 
ATOM   4319 C CG  . LEU B 2 263 ? 78.821  86.693  91.300  1.00 106.17 ? 252 LEU B CG  1 
ATOM   4320 C CD1 . LEU B 2 263 ? 78.201  85.597  92.131  1.00 106.17 ? 252 LEU B CD1 1 
ATOM   4321 C CD2 . LEU B 2 263 ? 77.750  87.638  90.791  1.00 106.17 ? 252 LEU B CD2 1 
ATOM   4322 N N   . SER B 2 264 ? 82.348  89.321  92.664  1.00 105.85 ? 253 SER B N   1 
ATOM   4323 C CA  . SER B 2 264 ? 83.257  89.964  93.604  1.00 105.85 ? 253 SER B CA  1 
ATOM   4324 C C   . SER B 2 264 ? 83.396  91.459  93.361  1.00 105.85 ? 253 SER B C   1 
ATOM   4325 O O   . SER B 2 264 ? 83.987  92.150  94.199  1.00 105.85 ? 253 SER B O   1 
ATOM   4326 C CB  . SER B 2 264 ? 84.635  89.309  93.545  1.00 105.85 ? 253 SER B CB  1 
ATOM   4327 O OG  . SER B 2 264 ? 85.556  90.006  94.366  1.00 105.85 ? 253 SER B OG  1 
ATOM   4328 N N   . SER B 2 265 ? 82.880  91.977  92.245  1.00 107.25 ? 254 SER B N   1 
ATOM   4329 C CA  . SER B 2 265 ? 82.813  93.425  92.079  1.00 107.25 ? 254 SER B CA  1 
ATOM   4330 C C   . SER B 2 265 ? 81.702  94.013  92.936  1.00 107.25 ? 254 SER B C   1 
ATOM   4331 O O   . SER B 2 265 ? 81.849  95.109  93.489  1.00 107.25 ? 254 SER B O   1 
ATOM   4332 C CB  . SER B 2 265 ? 82.609  93.785  90.610  1.00 107.25 ? 254 SER B CB  1 
ATOM   4333 O OG  . SER B 2 265 ? 82.494  95.186  90.448  1.00 107.25 ? 254 SER B OG  1 
ATOM   4334 N N   . LEU B 2 266 ? 80.585  93.298  93.058  1.00 103.28 ? 255 LEU B N   1 
ATOM   4335 C CA  . LEU B 2 266 ? 79.543  93.640  94.015  1.00 103.28 ? 255 LEU B CA  1 
ATOM   4336 C C   . LEU B 2 266 ? 80.023  93.541  95.453  1.00 103.28 ? 255 LEU B C   1 
ATOM   4337 O O   . LEU B 2 266 ? 79.304  93.968  96.358  1.00 103.28 ? 255 LEU B O   1 
ATOM   4338 C CB  . LEU B 2 266 ? 78.326  92.732  93.826  1.00 103.28 ? 255 LEU B CB  1 
ATOM   4339 C CG  . LEU B 2 266 ? 77.782  92.571  92.409  1.00 103.28 ? 255 LEU B CG  1 
ATOM   4340 C CD1 . LEU B 2 266 ? 76.542  91.698  92.413  1.00 103.28 ? 255 LEU B CD1 1 
ATOM   4341 C CD2 . LEU B 2 266 ? 77.484  93.920  91.798  1.00 103.28 ? 255 LEU B CD2 1 
ATOM   4342 N N   . LYS B 2 267 ? 81.209  92.976  95.675  1.00 98.36  ? 256 LYS B N   1 
ATOM   4343 C CA  . LYS B 2 267 ? 81.778  92.801  97.009  1.00 98.36  ? 256 LYS B CA  1 
ATOM   4344 C C   . LYS B 2 267 ? 80.830  92.026  97.920  1.00 98.36  ? 256 LYS B C   1 
ATOM   4345 O O   . LYS B 2 267 ? 80.383  92.515  98.960  1.00 98.36  ? 256 LYS B O   1 
ATOM   4346 C CB  . LYS B 2 267 ? 82.158  94.147  97.624  1.00 98.36  ? 256 LYS B CB  1 
ATOM   4347 C CG  . LYS B 2 267 ? 82.953  95.046  96.698  1.00 98.36  ? 256 LYS B CG  1 
ATOM   4348 C CD  . LYS B 2 267 ? 83.628  96.160  97.475  1.00 98.36  ? 256 LYS B CD  1 
ATOM   4349 C CE  . LYS B 2 267 ? 84.586  95.597  98.509  1.00 98.36  ? 256 LYS B CE  1 
ATOM   4350 N NZ  . LYS B 2 267 ? 85.211  96.667  99.330  1.00 98.36  ? 256 LYS B NZ  1 
ATOM   4351 N N   . VAL B 2 268 ? 80.519  90.802  97.514  1.00 90.00  ? 257 VAL B N   1 
ATOM   4352 C CA  . VAL B 2 268 ? 79.761  89.893  98.361  1.00 90.00  ? 257 VAL B CA  1 
ATOM   4353 C C   . VAL B 2 268 ? 80.717  88.886  98.981  1.00 90.00  ? 257 VAL B C   1 
ATOM   4354 O O   . VAL B 2 268 ? 81.810  88.632  98.464  1.00 90.00  ? 257 VAL B O   1 
ATOM   4355 C CB  . VAL B 2 268 ? 78.645  89.192  97.564  1.00 90.00  ? 257 VAL B CB  1 
ATOM   4356 C CG1 . VAL B 2 268 ? 77.845  90.202  96.771  1.00 90.00  ? 257 VAL B CG1 1 
ATOM   4357 C CG2 . VAL B 2 268 ? 79.231  88.141  96.660  1.00 90.00  ? 257 VAL B CG2 1 
ATOM   4358 N N   . LYS B 2 269 ? 80.309  88.316  100.113 1.00 85.70  ? 258 LYS B N   1 
ATOM   4359 C CA  . LYS B 2 269 ? 81.090  87.278  100.769 1.00 85.70  ? 258 LYS B CA  1 
ATOM   4360 C C   . LYS B 2 269 ? 80.256  86.014  100.866 1.00 85.70  ? 258 LYS B C   1 
ATOM   4361 O O   . LYS B 2 269 ? 80.320  85.289  101.862 1.00 85.70  ? 258 LYS B O   1 
ATOM   4362 C CB  . LYS B 2 269 ? 81.556  87.729  102.154 1.00 85.70  ? 258 LYS B CB  1 
ATOM   4363 C CG  . LYS B 2 269 ? 82.402  88.984  102.130 1.00 85.70  ? 258 LYS B CG  1 
ATOM   4364 C CD  . LYS B 2 269 ? 83.638  88.790  101.274 1.00 85.70  ? 258 LYS B CD  1 
ATOM   4365 C CE  . LYS B 2 269 ? 84.576  89.980  101.377 1.00 85.70  ? 258 LYS B CE  1 
ATOM   4366 N NZ  . LYS B 2 269 ? 84.028  91.192  100.711 1.00 85.70  ? 258 LYS B NZ  1 
ATOM   4367 N N   . GLY B 2 270 ? 79.483  85.744  99.830  1.00 88.51  ? 259 GLY B N   1 
ATOM   4368 C CA  . GLY B 2 270 ? 78.657  84.558  99.796  1.00 88.51  ? 259 GLY B CA  1 
ATOM   4369 C C   . GLY B 2 270 ? 78.091  84.348  98.410  1.00 88.51  ? 259 GLY B C   1 
ATOM   4370 O O   . GLY B 2 270 ? 78.303  85.143  97.496  1.00 88.51  ? 259 GLY B O   1 
ATOM   4371 N N   . LEU B 2 271 ? 77.357  83.250  98.281  1.00 96.77  ? 260 LEU B N   1 
ATOM   4372 C CA  . LEU B 2 271 ? 76.757  82.836  97.023  1.00 96.77  ? 260 LEU B CA  1 
ATOM   4373 C C   . LEU B 2 271 ? 75.868  81.644  97.317  1.00 96.77  ? 260 LEU B C   1 
ATOM   4374 O O   . LEU B 2 271 ? 76.150  80.864  98.228  1.00 96.77  ? 260 LEU B O   1 
ATOM   4375 C CB  . LEU B 2 271 ? 77.830  82.472  95.989  1.00 96.77  ? 260 LEU B CB  1 
ATOM   4376 C CG  . LEU B 2 271 ? 77.437  82.043  94.576  1.00 96.77  ? 260 LEU B CG  1 
ATOM   4377 C CD1 . LEU B 2 271 ? 78.545  82.432  93.636  1.00 96.77  ? 260 LEU B CD1 1 
ATOM   4378 C CD2 . LEU B 2 271 ? 77.206  80.547  94.499  1.00 96.77  ? 260 LEU B CD2 1 
ATOM   4379 N N   . VAL B 2 272 ? 74.796  81.506  96.544  1.00 102.08 ? 261 VAL B N   1 
ATOM   4380 C CA  . VAL B 2 272 ? 73.881  80.388  96.729  1.00 102.08 ? 261 VAL B CA  1 
ATOM   4381 C C   . VAL B 2 272 ? 73.481  79.820  95.374  1.00 102.08 ? 261 VAL B C   1 
ATOM   4382 O O   . VAL B 2 272 ? 72.634  80.388  94.674  1.00 102.08 ? 261 VAL B O   1 
ATOM   4383 C CB  . VAL B 2 272 ? 72.638  80.805  97.539  1.00 102.08 ? 261 VAL B CB  1 
ATOM   4384 C CG1 . VAL B 2 272 ? 71.606  79.709  97.499  1.00 102.08 ? 261 VAL B CG1 1 
ATOM   4385 C CG2 . VAL B 2 272 ? 73.002  81.111  98.979  1.00 102.08 ? 261 VAL B CG2 1 
ATOM   4386 N N   . LEU B 2 273 ? 74.090  78.706  94.986  1.00 110.65 ? 262 LEU B N   1 
ATOM   4387 C CA  . LEU B 2 273 ? 73.642  78.013  93.789  1.00 110.65 ? 262 LEU B CA  1 
ATOM   4388 C C   . LEU B 2 273 ? 72.276  77.384  94.021  1.00 110.65 ? 262 LEU B C   1 
ATOM   4389 O O   . LEU B 2 273 ? 71.903  77.045  95.146  1.00 110.65 ? 262 LEU B O   1 
ATOM   4390 C CB  . LEU B 2 273 ? 74.639  76.938  93.371  1.00 110.65 ? 262 LEU B CB  1 
ATOM   4391 C CG  . LEU B 2 273 ? 76.028  77.388  92.928  1.00 110.65 ? 262 LEU B CG  1 
ATOM   4392 C CD1 . LEU B 2 273 ? 76.784  76.217  92.326  1.00 110.65 ? 262 LEU B CD1 1 
ATOM   4393 C CD2 . LEU B 2 273 ? 75.908  78.506  91.918  1.00 110.65 ? 262 LEU B CD2 1 
ATOM   4394 N N   . GLY B 2 274 ? 71.529  77.227  92.937  1.00 124.83 ? 263 GLY B N   1 
ATOM   4395 C CA  . GLY B 2 274 ? 70.236  76.598  93.004  1.00 124.83 ? 263 GLY B CA  1 
ATOM   4396 C C   . GLY B 2 274 ? 70.372  75.105  93.195  1.00 124.83 ? 263 GLY B C   1 
ATOM   4397 O O   . GLY B 2 274 ? 71.479  74.560  93.211  1.00 124.83 ? 263 GLY B O   1 
ATOM   4398 N N   . PRO B 2 275 ? 69.247  74.411  93.347  1.00 141.26 ? 264 PRO B N   1 
ATOM   4399 C CA  . PRO B 2 275 ? 69.310  72.956  93.526  1.00 141.26 ? 264 PRO B CA  1 
ATOM   4400 C C   . PRO B 2 275 ? 69.884  72.272  92.299  1.00 141.26 ? 264 PRO B C   1 
ATOM   4401 O O   . PRO B 2 275 ? 69.256  72.236  91.236  1.00 141.26 ? 264 PRO B O   1 
ATOM   4402 C CB  . PRO B 2 275 ? 67.848  72.561  93.770  1.00 141.26 ? 264 PRO B CB  1 
ATOM   4403 C CG  . PRO B 2 275 ? 67.153  73.831  94.134  1.00 141.26 ? 264 PRO B CG  1 
ATOM   4404 C CD  . PRO B 2 275 ? 67.869  74.919  93.410  1.00 141.26 ? 264 PRO B CD  1 
ATOM   4405 N N   . ILE B 2 276 ? 71.089  71.720  92.449  1.00 146.01 ? 265 ILE B N   1 
ATOM   4406 C CA  . ILE B 2 276 ? 71.808  71.106  91.338  1.00 146.01 ? 265 ILE B CA  1 
ATOM   4407 C C   . ILE B 2 276 ? 71.690  69.590  91.328  1.00 146.01 ? 265 ILE B C   1 
ATOM   4408 O O   . ILE B 2 276 ? 72.200  68.947  90.396  1.00 146.01 ? 265 ILE B O   1 
ATOM   4409 C CB  . ILE B 2 276 ? 73.291  71.534  91.351  1.00 146.01 ? 265 ILE B CB  1 
ATOM   4410 C CG1 . ILE B 2 276 ? 73.934  71.184  92.692  1.00 146.01 ? 265 ILE B CG1 1 
ATOM   4411 C CG2 . ILE B 2 276 ? 73.417  73.021  91.070  1.00 146.01 ? 265 ILE B CG2 1 
ATOM   4412 C CD1 . ILE B 2 276 ? 75.410  71.499  92.758  1.00 146.01 ? 265 ILE B CD1 1 
ATOM   4413 N N   . HIS B 2 277 ? 71.039  68.999  92.325  1.00 156.85 ? 266 HIS B N   1 
ATOM   4414 C CA  . HIS B 2 277 ? 70.774  67.569  92.307  1.00 156.85 ? 266 HIS B CA  1 
ATOM   4415 C C   . HIS B 2 277 ? 69.754  67.233  91.226  1.00 156.85 ? 266 HIS B C   1 
ATOM   4416 O O   . HIS B 2 277 ? 68.890  68.044  90.881  1.00 156.85 ? 266 HIS B O   1 
ATOM   4417 C CB  . HIS B 2 277 ? 70.257  67.110  93.667  1.00 156.85 ? 266 HIS B CB  1 
ATOM   4418 C CG  . HIS B 2 277 ? 68.869  67.580  93.968  1.00 156.85 ? 266 HIS B CG  1 
ATOM   4419 N ND1 . HIS B 2 277 ? 68.540  68.915  94.059  1.00 156.85 ? 266 HIS B ND1 1 
ATOM   4420 C CD2 . HIS B 2 277 ? 67.723  66.894  94.188  1.00 156.85 ? 266 HIS B CD2 1 
ATOM   4421 C CE1 . HIS B 2 277 ? 67.252  69.031  94.328  1.00 156.85 ? 266 HIS B CE1 1 
ATOM   4422 N NE2 . HIS B 2 277 ? 66.734  67.819  94.411  1.00 156.85 ? 266 HIS B NE2 1 
ATOM   4423 N N   . LYS B 2 278 ? 69.861  66.021  90.687  1.00 162.18 ? 267 LYS B N   1 
ATOM   4424 C CA  . LYS B 2 278 ? 68.930  65.581  89.657  1.00 162.18 ? 267 LYS B CA  1 
ATOM   4425 C C   . LYS B 2 278 ? 67.535  65.414  90.247  1.00 162.18 ? 267 LYS B C   1 
ATOM   4426 O O   . LYS B 2 278 ? 67.329  64.630  91.178  1.00 162.18 ? 267 LYS B O   1 
ATOM   4427 C CB  . LYS B 2 278 ? 69.415  64.271  89.033  1.00 162.18 ? 267 LYS B CB  1 
ATOM   4428 C CG  . LYS B 2 278 ? 68.678  63.850  87.763  1.00 162.18 ? 267 LYS B CG  1 
ATOM   4429 C CD  . LYS B 2 278 ? 67.451  62.995  88.052  1.00 162.18 ? 267 LYS B CD  1 
ATOM   4430 C CE  . LYS B 2 278 ? 66.721  62.630  86.769  1.00 162.18 ? 267 LYS B CE  1 
ATOM   4431 N NZ  . LYS B 2 278 ? 65.286  62.316  87.012  1.00 162.18 ? 267 LYS B NZ  1 
ATOM   4432 N N   . ASN B 2 279 ? 66.575  66.156  89.698  1.00 162.38 ? 268 ASN B N   1 
ATOM   4433 C CA  . ASN B 2 279 ? 65.190  66.096  90.155  1.00 162.38 ? 268 ASN B CA  1 
ATOM   4434 C C   . ASN B 2 279 ? 64.278  66.249  88.950  1.00 162.38 ? 268 ASN B C   1 
ATOM   4435 O O   . ASN B 2 279 ? 64.454  67.176  88.155  1.00 162.38 ? 268 ASN B O   1 
ATOM   4436 C CB  . ASN B 2 279 ? 64.902  67.186  91.189  1.00 162.38 ? 268 ASN B CB  1 
ATOM   4437 C CG  . ASN B 2 279 ? 63.445  67.225  91.608  1.00 162.38 ? 268 ASN B CG  1 
ATOM   4438 O OD1 . ASN B 2 279 ? 62.748  66.210  91.578  1.00 162.38 ? 268 ASN B OD1 1 
ATOM   4439 N ND2 . ASN B 2 279 ? 62.975  68.404  91.997  1.00 162.38 ? 268 ASN B ND2 1 
ATOM   4440 N N   . GLN B 2 280 ? 63.313  65.340  88.813  1.00 166.17 ? 269 GLN B N   1 
ATOM   4441 C CA  . GLN B 2 280 ? 62.364  65.380  87.705  1.00 166.17 ? 269 GLN B CA  1 
ATOM   4442 C C   . GLN B 2 280 ? 60.980  65.849  88.149  1.00 166.17 ? 269 GLN B C   1 
ATOM   4443 O O   . GLN B 2 280 ? 60.459  66.830  87.610  1.00 166.17 ? 269 GLN B O   1 
ATOM   4444 C CB  . GLN B 2 280 ? 62.299  64.004  87.010  1.00 166.17 ? 269 GLN B CB  1 
ATOM   4445 C CG  . GLN B 2 280 ? 61.717  62.830  87.813  1.00 166.17 ? 269 GLN B CG  1 
ATOM   4446 C CD  . GLN B 2 280 ? 62.434  62.580  89.126  1.00 166.17 ? 269 GLN B CD  1 
ATOM   4447 O OE1 . GLN B 2 280 ? 63.606  62.922  89.281  1.00 166.17 ? 269 GLN B OE1 1 
ATOM   4448 N NE2 . GLN B 2 280 ? 61.729  61.990  90.083  1.00 166.17 ? 269 GLN B NE2 1 
ATOM   4449 N N   . LYS B 2 281 ? 60.389  65.188  89.138  1.00 166.06 ? 270 LYS B N   1 
ATOM   4450 C CA  . LYS B 2 281 ? 59.013  65.442  89.564  1.00 166.06 ? 270 LYS B CA  1 
ATOM   4451 C C   . LYS B 2 281 ? 58.786  64.735  90.897  1.00 166.06 ? 270 LYS B C   1 
ATOM   4452 O O   . LYS B 2 281 ? 59.737  64.323  91.573  1.00 166.06 ? 270 LYS B O   1 
ATOM   4453 C CB  . LYS B 2 281 ? 57.999  64.996  88.508  1.00 166.06 ? 270 LYS B CB  1 
ATOM   4454 C CG  . LYS B 2 281 ? 57.474  66.122  87.619  1.00 166.06 ? 270 LYS B CG  1 
ATOM   4455 C CD  . LYS B 2 281 ? 56.810  67.237  88.423  1.00 166.06 ? 270 LYS B CD  1 
ATOM   4456 C CE  . LYS B 2 281 ? 55.744  66.709  89.374  1.00 166.06 ? 270 LYS B CE  1 
ATOM   4457 N NZ  . LYS B 2 281 ? 55.242  67.775  90.283  1.00 166.06 ? 270 LYS B NZ  1 
ATOM   4458 N N   . ASP B 2 282 ? 57.507  64.613  91.273  1.00 169.62 ? 271 ASP B N   1 
ATOM   4459 C CA  . ASP B 2 282 ? 57.102  64.071  92.568  1.00 169.62 ? 271 ASP B CA  1 
ATOM   4460 C C   . ASP B 2 282 ? 57.784  62.746  92.905  1.00 169.62 ? 271 ASP B C   1 
ATOM   4461 O O   . ASP B 2 282 ? 57.924  62.409  94.085  1.00 169.62 ? 271 ASP B O   1 
ATOM   4462 C CB  . ASP B 2 282 ? 55.579  63.895  92.584  1.00 169.62 ? 271 ASP B CB  1 
ATOM   4463 C CG  . ASP B 2 282 ? 55.032  63.553  93.961  1.00 169.62 ? 271 ASP B CG  1 
ATOM   4464 O OD1 . ASP B 2 282 ? 55.771  63.674  94.959  1.00 169.62 ? 271 ASP B OD1 1 
ATOM   4465 O OD2 . ASP B 2 282 ? 53.850  63.159  94.041  1.00 169.62 ? 271 ASP B OD2 1 
ATOM   4466 N N   . ASP B 2 283 ? 58.205  61.982  91.896  1.00 171.89 ? 272 ASP B N   1 
ATOM   4467 C CA  . ASP B 2 283 ? 58.796  60.668  92.138  1.00 171.89 ? 272 ASP B CA  1 
ATOM   4468 C C   . ASP B 2 283 ? 59.977  60.771  93.096  1.00 171.89 ? 272 ASP B C   1 
ATOM   4469 O O   . ASP B 2 283 ? 60.990  61.404  92.786  1.00 171.89 ? 272 ASP B O   1 
ATOM   4470 C CB  . ASP B 2 283 ? 59.233  60.038  90.816  1.00 171.89 ? 272 ASP B CB  1 
ATOM   4471 C CG  . ASP B 2 283 ? 59.824  58.652  90.997  1.00 171.89 ? 272 ASP B CG  1 
ATOM   4472 O OD1 . ASP B 2 283 ? 61.033  58.549  91.292  1.00 171.89 ? 272 ASP B OD1 1 
ATOM   4473 O OD2 . ASP B 2 283 ? 59.076  57.664  90.845  1.00 171.89 ? 272 ASP B OD2 1 
ATOM   4474 N N   . VAL B 2 284 ? 59.837  60.144  94.264  1.00 171.70 ? 273 VAL B N   1 
ATOM   4475 C CA  . VAL B 2 284 ? 60.849  60.254  95.308  1.00 171.70 ? 273 VAL B CA  1 
ATOM   4476 C C   . VAL B 2 284 ? 61.932  59.183  95.185  1.00 171.70 ? 273 VAL B C   1 
ATOM   4477 O O   . VAL B 2 284 ? 63.065  59.402  95.625  1.00 171.70 ? 273 VAL B O   1 
ATOM   4478 C CB  . VAL B 2 284 ? 60.186  60.202  96.697  1.00 171.70 ? 273 VAL B CB  1 
ATOM   4479 C CG1 . VAL B 2 284 ? 59.059  61.210  96.786  1.00 171.70 ? 273 VAL B CG1 1 
ATOM   4480 C CG2 . VAL B 2 284 ? 59.667  58.803  97.000  1.00 171.70 ? 273 VAL B CG2 1 
ATOM   4481 N N   . ALA B 2 285 ? 61.611  58.028  94.595  1.00 174.67 ? 274 ALA B N   1 
ATOM   4482 C CA  . ALA B 2 285 ? 62.539  56.904  94.597  1.00 174.67 ? 274 ALA B CA  1 
ATOM   4483 C C   . ALA B 2 285 ? 63.753  57.138  93.709  1.00 174.67 ? 274 ALA B C   1 
ATOM   4484 O O   . ALA B 2 285 ? 64.800  56.524  93.942  1.00 174.67 ? 274 ALA B O   1 
ATOM   4485 C CB  . ALA B 2 285 ? 61.817  55.628  94.161  1.00 174.67 ? 274 ALA B CB  1 
ATOM   4486 N N   . GLN B 2 286 ? 63.645  58.007  92.706  1.00 171.16 ? 275 GLN B N   1 
ATOM   4487 C CA  . GLN B 2 286 ? 64.758  58.289  91.809  1.00 171.16 ? 275 GLN B CA  1 
ATOM   4488 C C   . GLN B 2 286 ? 65.481  59.580  92.167  1.00 171.16 ? 275 GLN B C   1 
ATOM   4489 O O   . GLN B 2 286 ? 66.711  59.640  92.079  1.00 171.16 ? 275 GLN B O   1 
ATOM   4490 C CB  . GLN B 2 286 ? 64.261  58.351  90.358  1.00 171.16 ? 275 GLN B CB  1 
ATOM   4491 C CG  . GLN B 2 286 ? 65.357  58.372  89.293  1.00 171.16 ? 275 GLN B CG  1 
ATOM   4492 C CD  . GLN B 2 286 ? 65.989  59.735  89.104  1.00 171.16 ? 275 GLN B CD  1 
ATOM   4493 O OE1 . GLN B 2 286 ? 65.306  60.756  89.118  1.00 171.16 ? 275 GLN B OE1 1 
ATOM   4494 N NE2 . GLN B 2 286 ? 67.305  59.756  88.925  1.00 171.16 ? 275 GLN B NE2 1 
ATOM   4495 N N   . THR B 2 287 ? 64.743  60.611  92.572  1.00 168.36 ? 276 THR B N   1 
ATOM   4496 C CA  . THR B 2 287 ? 65.350  61.878  92.963  1.00 168.36 ? 276 THR B CA  1 
ATOM   4497 C C   . THR B 2 287 ? 66.199  61.694  94.216  1.00 168.36 ? 276 THR B C   1 
ATOM   4498 O O   . THR B 2 287 ? 65.673  61.385  95.290  1.00 168.36 ? 276 THR B O   1 
ATOM   4499 C CB  . THR B 2 287 ? 64.269  62.928  93.208  1.00 168.36 ? 276 THR B CB  1 
ATOM   4500 O OG1 . THR B 2 287 ? 63.333  62.920  92.122  1.00 168.36 ? 276 THR B OG1 1 
ATOM   4501 C CG2 . THR B 2 287 ? 64.884  64.311  93.343  1.00 168.36 ? 276 THR B CG2 1 
ATOM   4502 N N   . ASP B 2 288 ? 67.508  61.885  94.079  1.00 163.59 ? 277 ASP B N   1 
ATOM   4503 C CA  . ASP B 2 288 ? 68.419  61.883  95.211  1.00 163.59 ? 277 ASP B CA  1 
ATOM   4504 C C   . ASP B 2 288 ? 69.125  63.228  95.301  1.00 163.59 ? 277 ASP B C   1 
ATOM   4505 O O   . ASP B 2 288 ? 69.046  64.054  94.387  1.00 163.59 ? 277 ASP B O   1 
ATOM   4506 C CB  . ASP B 2 288 ? 69.457  60.758  95.119  1.00 163.59 ? 277 ASP B CB  1 
ATOM   4507 C CG  . ASP B 2 288 ? 70.435  60.950  93.975  1.00 163.59 ? 277 ASP B CG  1 
ATOM   4508 O OD1 . ASP B 2 288 ? 70.156  61.746  93.055  1.00 163.59 ? 277 ASP B OD1 1 
ATOM   4509 O OD2 . ASP B 2 288 ? 71.507  60.313  94.016  1.00 163.59 ? 277 ASP B OD2 1 
ATOM   4510 N N   . LEU B 2 289 ? 69.823  63.436  96.413  1.00 158.87 ? 278 LEU B N   1 
ATOM   4511 C CA  . LEU B 2 289 ? 70.452  64.711  96.716  1.00 158.87 ? 278 LEU B CA  1 
ATOM   4512 C C   . LEU B 2 289 ? 71.958  64.695  96.481  1.00 158.87 ? 278 LEU B C   1 
ATOM   4513 O O   . LEU B 2 289 ? 72.651  65.632  96.891  1.00 158.87 ? 278 LEU B O   1 
ATOM   4514 C CB  . LEU B 2 289 ? 70.139  65.101  98.161  1.00 158.87 ? 278 LEU B CB  1 
ATOM   4515 C CG  . LEU B 2 289 ? 70.099  66.584  98.521  1.00 158.87 ? 278 LEU B CG  1 
ATOM   4516 C CD1 . LEU B 2 289 ? 69.403  67.375  97.429  1.00 158.87 ? 278 LEU B CD1 1 
ATOM   4517 C CD2 . LEU B 2 289 ? 69.378  66.755  99.843  1.00 158.87 ? 278 LEU B CD2 1 
ATOM   4518 N N   . LEU B 2 290 ? 72.481  63.657  95.829  1.00 156.37 ? 279 LEU B N   1 
ATOM   4519 C CA  . LEU B 2 290 ? 73.915  63.533  95.606  1.00 156.37 ? 279 LEU B CA  1 
ATOM   4520 C C   . LEU B 2 290 ? 74.328  63.618  94.146  1.00 156.37 ? 279 LEU B C   1 
ATOM   4521 O O   . LEU B 2 290 ? 75.380  64.189  93.853  1.00 156.37 ? 279 LEU B O   1 
ATOM   4522 C CB  . LEU B 2 290 ? 74.434  62.210  96.187  1.00 156.37 ? 279 LEU B CB  1 
ATOM   4523 C CG  . LEU B 2 290 ? 74.683  62.172  97.697  1.00 156.37 ? 279 LEU B CG  1 
ATOM   4524 C CD1 . LEU B 2 290 ? 73.401  61.862  98.454  1.00 156.37 ? 279 LEU B CD1 1 
ATOM   4525 C CD2 . LEU B 2 290 ? 75.771  61.165  98.039  1.00 156.37 ? 279 LEU B CD2 1 
ATOM   4526 N N   . GLN B 2 291 ? 73.539  63.072  93.224  1.00 161.16 ? 280 GLN B N   1 
ATOM   4527 C CA  . GLN B 2 291 ? 73.909  63.058  91.814  1.00 161.16 ? 280 GLN B CA  1 
ATOM   4528 C C   . GLN B 2 291 ? 73.677  64.427  91.190  1.00 161.16 ? 280 GLN B C   1 
ATOM   4529 O O   . GLN B 2 291 ? 72.554  64.942  91.204  1.00 161.16 ? 280 GLN B O   1 
ATOM   4530 C CB  . GLN B 2 291 ? 73.123  61.997  91.042  1.00 161.16 ? 280 GLN B CB  1 
ATOM   4531 C CG  . GLN B 2 291 ? 73.368  60.569  91.487  1.00 161.16 ? 280 GLN B CG  1 
ATOM   4532 C CD  . GLN B 2 291 ? 72.223  59.652  91.116  1.00 161.16 ? 280 GLN B CD  1 
ATOM   4533 O OE1 . GLN B 2 291 ? 71.968  58.654  91.788  1.00 161.16 ? 280 GLN B OE1 1 
ATOM   4534 N NE2 . GLN B 2 291 ? 71.522  59.990  90.041  1.00 161.16 ? 280 GLN B NE2 1 
ATOM   4535 N N   . ILE B 2 292 ? 74.749  65.016  90.656  1.00 157.61 ? 281 ILE B N   1 
ATOM   4536 C CA  . ILE B 2 292 ? 74.620  66.232  89.865  1.00 157.61 ? 281 ILE B CA  1 
ATOM   4537 C C   . ILE B 2 292 ? 73.698  65.967  88.687  1.00 157.61 ? 281 ILE B C   1 
ATOM   4538 O O   . ILE B 2 292 ? 73.866  64.982  87.957  1.00 157.61 ? 281 ILE B O   1 
ATOM   4539 C CB  . ILE B 2 292 ? 75.999  66.708  89.387  1.00 157.61 ? 281 ILE B CB  1 
ATOM   4540 C CG1 . ILE B 2 292 ? 76.806  67.293  90.546  1.00 157.61 ? 281 ILE B CG1 1 
ATOM   4541 C CG2 . ILE B 2 292 ? 75.856  67.722  88.256  1.00 157.61 ? 281 ILE B CG2 1 
ATOM   4542 C CD1 . ILE B 2 292 ? 76.450  68.711  90.879  1.00 157.61 ? 281 ILE B CD1 1 
ATOM   4543 N N   . ASP B 2 293 ? 72.710  66.832  88.504  1.00 159.44 ? 282 ASP B N   1 
ATOM   4544 C CA  . ASP B 2 293 ? 71.912  66.799  87.289  1.00 159.44 ? 282 ASP B CA  1 
ATOM   4545 C C   . ASP B 2 293 ? 72.826  67.058  86.097  1.00 159.44 ? 282 ASP B C   1 
ATOM   4546 O O   . ASP B 2 293 ? 73.370  68.166  85.974  1.00 159.44 ? 282 ASP B O   1 
ATOM   4547 C CB  . ASP B 2 293 ? 70.795  67.836  87.349  1.00 159.44 ? 282 ASP B CB  1 
ATOM   4548 C CG  . ASP B 2 293 ? 69.663  67.529  86.391  1.00 159.44 ? 282 ASP B CG  1 
ATOM   4549 O OD1 . ASP B 2 293 ? 69.858  67.701  85.170  1.00 159.44 ? 282 ASP B OD1 1 
ATOM   4550 O OD2 . ASP B 2 293 ? 68.579  67.118  86.856  1.00 159.44 ? 282 ASP B OD2 1 
ATOM   4551 N N   . PRO B 2 294 ? 73.032  66.080  85.212  1.00 158.66 ? 283 PRO B N   1 
ATOM   4552 C CA  . PRO B 2 294 ? 74.053  66.239  84.163  1.00 158.66 ? 283 PRO B CA  1 
ATOM   4553 C C   . PRO B 2 294 ? 73.792  67.395  83.215  1.00 158.66 ? 283 PRO B C   1 
ATOM   4554 O O   . PRO B 2 294 ? 74.744  67.900  82.608  1.00 158.66 ? 283 PRO B O   1 
ATOM   4555 C CB  . PRO B 2 294 ? 74.013  64.892  83.428  1.00 158.66 ? 283 PRO B CB  1 
ATOM   4556 C CG  . PRO B 2 294 ? 72.660  64.334  83.725  1.00 158.66 ? 283 PRO B CG  1 
ATOM   4557 C CD  . PRO B 2 294 ? 72.320  64.796  85.108  1.00 158.66 ? 283 PRO B CD  1 
ATOM   4558 N N   . ASN B 2 295 ? 72.539  67.832  83.066  1.00 159.25 ? 284 ASN B N   1 
ATOM   4559 C CA  . ASN B 2 295 ? 72.245  68.955  82.184  1.00 159.25 ? 284 ASN B CA  1 
ATOM   4560 C C   . ASN B 2 295 ? 72.876  70.255  82.664  1.00 159.25 ? 284 ASN B C   1 
ATOM   4561 O O   . ASN B 2 295 ? 73.006  71.194  81.871  1.00 159.25 ? 284 ASN B O   1 
ATOM   4562 C CB  . ASN B 2 295 ? 70.733  69.122  82.037  1.00 159.25 ? 284 ASN B CB  1 
ATOM   4563 C CG  . ASN B 2 295 ? 70.034  67.816  81.713  1.00 159.25 ? 284 ASN B CG  1 
ATOM   4564 O OD1 . ASN B 2 295 ? 70.007  66.893  82.526  1.00 159.25 ? 284 ASN B OD1 1 
ATOM   4565 N ND2 . ASN B 2 295 ? 69.466  67.732  80.516  1.00 159.25 ? 284 ASN B ND2 1 
ATOM   4566 N N   . PHE B 2 296 ? 73.270  70.334  83.934  1.00 154.55 ? 285 PHE B N   1 
ATOM   4567 C CA  . PHE B 2 296 ? 74.012  71.482  84.436  1.00 154.55 ? 285 PHE B CA  1 
ATOM   4568 C C   . PHE B 2 296 ? 75.517  71.274  84.414  1.00 154.55 ? 285 PHE B C   1 
ATOM   4569 O O   . PHE B 2 296 ? 76.263  72.250  84.296  1.00 154.55 ? 285 PHE B O   1 
ATOM   4570 C CB  . PHE B 2 296 ? 73.581  71.821  85.867  1.00 154.55 ? 285 PHE B CB  1 
ATOM   4571 C CG  . PHE B 2 296 ? 72.116  72.109  86.008  1.00 154.55 ? 285 PHE B CG  1 
ATOM   4572 C CD1 . PHE B 2 296 ? 71.602  73.344  85.651  1.00 154.55 ? 285 PHE B CD1 1 
ATOM   4573 C CD2 . PHE B 2 296 ? 71.253  71.149  86.505  1.00 154.55 ? 285 PHE B CD2 1 
ATOM   4574 C CE1 . PHE B 2 296 ? 70.254  73.613  85.782  1.00 154.55 ? 285 PHE B CE1 1 
ATOM   4575 C CE2 . PHE B 2 296 ? 69.904  71.411  86.639  1.00 154.55 ? 285 PHE B CE2 1 
ATOM   4576 C CZ  . PHE B 2 296 ? 69.404  72.645  86.277  1.00 154.55 ? 285 PHE B CZ  1 
ATOM   4577 N N   . GLY B 2 297 ? 75.977  70.043  84.518  1.00 156.44 ? 286 GLY B N   1 
ATOM   4578 C CA  . GLY B 2 297 ? 77.398  69.768  84.502  1.00 156.44 ? 286 GLY B CA  1 
ATOM   4579 C C   . GLY B 2 297 ? 77.694  68.453  85.205  1.00 156.44 ? 286 GLY B C   1 
ATOM   4580 O O   . GLY B 2 297 ? 76.871  67.540  85.207  1.00 156.44 ? 286 GLY B O   1 
ATOM   4581 N N   . SER B 2 298 ? 78.890  68.388  85.788  1.00 151.71 ? 287 SER B N   1 
ATOM   4582 C CA  . SER B 2 298 ? 79.361  67.187  86.465  1.00 151.71 ? 287 SER B CA  1 
ATOM   4583 C C   . SER B 2 298 ? 79.888  67.525  87.852  1.00 151.71 ? 287 SER B C   1 
ATOM   4584 O O   . SER B 2 298 ? 79.638  68.619  88.369  1.00 151.71 ? 287 SER B O   1 
ATOM   4585 C CB  . SER B 2 298 ? 80.444  66.493  85.637  1.00 151.71 ? 287 SER B CB  1 
ATOM   4586 O OG  . SER B 2 298 ? 80.998  65.399  86.345  1.00 151.71 ? 287 SER B OG  1 
ATOM   4587 N N   . LYS B 2 299 ? 80.596  66.584  88.474  1.00 148.35 ? 288 LYS B N   1 
ATOM   4588 C CA  . LYS B 2 299 ? 81.226  66.838  89.763  1.00 148.35 ? 288 LYS B CA  1 
ATOM   4589 C C   . LYS B 2 299 ? 82.515  67.641  89.645  1.00 148.35 ? 288 LYS B C   1 
ATOM   4590 O O   . LYS B 2 299 ? 82.714  68.586  90.416  1.00 148.35 ? 288 LYS B O   1 
ATOM   4591 C CB  . LYS B 2 299 ? 81.522  65.516  90.477  1.00 148.35 ? 288 LYS B CB  1 
ATOM   4592 C CG  . LYS B 2 299 ? 80.305  64.634  90.702  1.00 148.35 ? 288 LYS B CG  1 
ATOM   4593 C CD  . LYS B 2 299 ? 79.429  65.173  91.818  1.00 148.35 ? 288 LYS B CD  1 
ATOM   4594 C CE  . LYS B 2 299 ? 78.204  64.297  92.025  1.00 148.35 ? 288 LYS B CE  1 
ATOM   4595 N NZ  . LYS B 2 299 ? 78.565  62.957  92.559  1.00 148.35 ? 288 LYS B NZ  1 
ATOM   4596 N N   . GLU B 2 300 ? 83.382  67.303  88.687  1.00 148.53 ? 289 GLU B N   1 
ATOM   4597 C CA  . GLU B 2 300 ? 84.721  67.886  88.643  1.00 148.53 ? 289 GLU B CA  1 
ATOM   4598 C C   . GLU B 2 300 ? 84.694  69.367  88.278  1.00 148.53 ? 289 GLU B C   1 
ATOM   4599 O O   . GLU B 2 300 ? 85.426  70.167  88.875  1.00 148.53 ? 289 GLU B O   1 
ATOM   4600 C CB  . GLU B 2 300 ? 85.608  67.110  87.663  1.00 148.53 ? 289 GLU B CB  1 
ATOM   4601 C CG  . GLU B 2 300 ? 85.021  66.883  86.272  1.00 148.53 ? 289 GLU B CG  1 
ATOM   4602 C CD  . GLU B 2 300 ? 84.019  65.743  86.222  1.00 148.53 ? 289 GLU B CD  1 
ATOM   4603 O OE1 . GLU B 2 300 ? 83.480  65.473  85.128  1.00 148.53 ? 289 GLU B OE1 1 
ATOM   4604 O OE2 . GLU B 2 300 ? 83.769  65.118  87.274  1.00 148.53 ? 289 GLU B OE2 1 
ATOM   4605 N N   . ASP B 2 301 ? 83.881  69.753  87.292  1.00 146.84 ? 290 ASP B N   1 
ATOM   4606 C CA  . ASP B 2 301 ? 83.719  71.174  87.008  1.00 146.84 ? 290 ASP B CA  1 
ATOM   4607 C C   . ASP B 2 301 ? 83.153  71.912  88.213  1.00 146.84 ? 290 ASP B C   1 
ATOM   4608 O O   . ASP B 2 301 ? 83.523  73.064  88.468  1.00 146.84 ? 290 ASP B O   1 
ATOM   4609 C CB  . ASP B 2 301 ? 82.833  71.377  85.778  1.00 146.84 ? 290 ASP B CB  1 
ATOM   4610 C CG  . ASP B 2 301 ? 81.617  70.485  85.787  1.00 146.84 ? 290 ASP B CG  1 
ATOM   4611 O OD1 . ASP B 2 301 ? 81.513  69.655  86.709  1.00 146.84 ? 290 ASP B OD1 1 
ATOM   4612 O OD2 . ASP B 2 301 ? 80.771  70.610  84.878  1.00 146.84 ? 290 ASP B OD2 1 
ATOM   4613 N N   . PHE B 2 302 ? 82.275  71.259  88.976  1.00 146.05 ? 291 PHE B N   1 
ATOM   4614 C CA  . PHE B 2 302 ? 81.760  71.859  90.202  1.00 146.05 ? 291 PHE B CA  1 
ATOM   4615 C C   . PHE B 2 302 ? 82.881  72.096  91.208  1.00 146.05 ? 291 PHE B C   1 
ATOM   4616 O O   . PHE B 2 302 ? 82.948  73.156  91.843  1.00 146.05 ? 291 PHE B O   1 
ATOM   4617 C CB  . PHE B 2 302 ? 80.672  70.965  90.797  1.00 146.05 ? 291 PHE B CB  1 
ATOM   4618 C CG  . PHE B 2 302 ? 80.215  71.386  92.163  1.00 146.05 ? 291 PHE B CG  1 
ATOM   4619 C CD1 . PHE B 2 302 ? 79.823  72.692  92.406  1.00 146.05 ? 291 PHE B CD1 1 
ATOM   4620 C CD2 . PHE B 2 302 ? 80.176  70.475  93.204  1.00 146.05 ? 291 PHE B CD2 1 
ATOM   4621 C CE1 . PHE B 2 302 ? 79.400  73.079  93.660  1.00 146.05 ? 291 PHE B CE1 1 
ATOM   4622 C CE2 . PHE B 2 302 ? 79.756  70.858  94.461  1.00 146.05 ? 291 PHE B CE2 1 
ATOM   4623 C CZ  . PHE B 2 302 ? 79.367  72.162  94.689  1.00 146.05 ? 291 PHE B CZ  1 
ATOM   4624 N N   . ASP B 2 303 ? 83.773  71.115  91.370  1.00 144.35 ? 292 ASP B N   1 
ATOM   4625 C CA  . ASP B 2 303 ? 84.888  71.289  92.298  1.00 144.35 ? 292 ASP B CA  1 
ATOM   4626 C C   . ASP B 2 303 ? 85.813  72.407  91.837  1.00 144.35 ? 292 ASP B C   1 
ATOM   4627 O O   . ASP B 2 303 ? 86.334  73.173  92.654  1.00 144.35 ? 292 ASP B O   1 
ATOM   4628 C CB  . ASP B 2 303 ? 85.673  69.985  92.465  1.00 144.35 ? 292 ASP B CB  1 
ATOM   4629 C CG  . ASP B 2 303 ? 84.787  68.800  92.784  1.00 144.35 ? 292 ASP B CG  1 
ATOM   4630 O OD1 . ASP B 2 303 ? 84.166  68.795  93.867  1.00 144.35 ? 292 ASP B OD1 1 
ATOM   4631 O OD2 . ASP B 2 303 ? 84.707  67.874  91.951  1.00 144.35 ? 292 ASP B OD2 1 
ATOM   4632 N N   . SER B 2 304 ? 86.040  72.510  90.525  1.00 138.49 ? 293 SER B N   1 
ATOM   4633 C CA  . SER B 2 304 ? 86.872  73.598  90.018  1.00 138.49 ? 293 SER B CA  1 
ATOM   4634 C C   . SER B 2 304 ? 86.216  74.949  90.274  1.00 138.49 ? 293 SER B C   1 
ATOM   4635 O O   . SER B 2 304 ? 86.894  75.927  90.611  1.00 138.49 ? 293 SER B O   1 
ATOM   4636 C CB  . SER B 2 304 ? 87.147  73.411  88.528  1.00 138.49 ? 293 SER B CB  1 
ATOM   4637 O OG  . SER B 2 304 ? 85.955  73.123  87.826  1.00 138.49 ? 293 SER B OG  1 
ATOM   4638 N N   . LEU B 2 305 ? 84.894  75.021  90.103  1.00 136.96 ? 294 LEU B N   1 
ATOM   4639 C CA  . LEU B 2 305 ? 84.154  76.226  90.463  1.00 136.96 ? 294 LEU B CA  1 
ATOM   4640 C C   . LEU B 2 305 ? 84.370  76.582  91.928  1.00 136.96 ? 294 LEU B C   1 
ATOM   4641 O O   . LEU B 2 305 ? 84.660  77.739  92.259  1.00 136.96 ? 294 LEU B O   1 
ATOM   4642 C CB  . LEU B 2 305 ? 82.666  76.021  90.170  1.00 136.96 ? 294 LEU B CB  1 
ATOM   4643 C CG  . LEU B 2 305 ? 81.644  77.063  90.632  1.00 136.96 ? 294 LEU B CG  1 
ATOM   4644 C CD1 . LEU B 2 305 ? 82.094  78.479  90.304  1.00 136.96 ? 294 LEU B CD1 1 
ATOM   4645 C CD2 . LEU B 2 305 ? 80.284  76.772  90.017  1.00 136.96 ? 294 LEU B CD2 1 
ATOM   4646 N N   . LEU B 2 306 ? 84.216  75.600  92.818  1.00 133.32 ? 295 LEU B N   1 
ATOM   4647 C CA  . LEU B 2 306 ? 84.423  75.841  94.244  1.00 133.32 ? 295 LEU B CA  1 
ATOM   4648 C C   . LEU B 2 306 ? 85.832  76.345  94.521  1.00 133.32 ? 295 LEU B C   1 
ATOM   4649 O O   . LEU B 2 306 ? 86.028  77.262  95.325  1.00 133.32 ? 295 LEU B O   1 
ATOM   4650 C CB  . LEU B 2 306 ? 84.145  74.570  95.045  1.00 133.32 ? 295 LEU B CB  1 
ATOM   4651 C CG  . LEU B 2 306 ? 82.785  73.901  94.875  1.00 133.32 ? 295 LEU B CG  1 
ATOM   4652 C CD1 . LEU B 2 306 ? 82.851  72.459  95.338  1.00 133.32 ? 295 LEU B CD1 1 
ATOM   4653 C CD2 . LEU B 2 306 ? 81.740  74.669  95.661  1.00 133.32 ? 295 LEU B CD2 1 
ATOM   4654 N N   . GLN B 2 307 ? 86.831  75.745  93.872  1.00 133.50 ? 296 GLN B N   1 
ATOM   4655 C CA  . GLN B 2 307 ? 88.214  76.131  94.134  1.00 133.50 ? 296 GLN B CA  1 
ATOM   4656 C C   . GLN B 2 307 ? 88.500  77.541  93.634  1.00 133.50 ? 296 GLN B C   1 
ATOM   4657 O O   . GLN B 2 307 ? 89.183  78.318  94.309  1.00 133.50 ? 296 GLN B O   1 
ATOM   4658 C CB  . GLN B 2 307 ? 89.173  75.125  93.496  1.00 133.50 ? 296 GLN B CB  1 
ATOM   4659 C CG  . GLN B 2 307 ? 89.335  73.842  94.297  1.00 133.50 ? 296 GLN B CG  1 
ATOM   4660 C CD  . GLN B 2 307 ? 89.271  72.597  93.436  1.00 133.50 ? 296 GLN B CD  1 
ATOM   4661 O OE1 . GLN B 2 307 ? 89.110  72.677  92.219  1.00 133.50 ? 296 GLN B OE1 1 
ATOM   4662 N NE2 . GLN B 2 307 ? 89.396  71.435  94.067  1.00 133.50 ? 296 GLN B NE2 1 
ATOM   4663 N N   . SER B 2 308 ? 87.972  77.895  92.461  1.00 129.73 ? 297 SER B N   1 
ATOM   4664 C CA  . SER B 2 308 ? 88.149  79.254  91.958  1.00 129.73 ? 297 SER B CA  1 
ATOM   4665 C C   . SER B 2 308 ? 87.453  80.267  92.859  1.00 129.73 ? 297 SER B C   1 
ATOM   4666 O O   . SER B 2 308 ? 87.990  81.351  93.124  1.00 129.73 ? 297 SER B O   1 
ATOM   4667 C CB  . SER B 2 308 ? 87.625  79.352  90.527  1.00 129.73 ? 297 SER B CB  1 
ATOM   4668 O OG  . SER B 2 308 ? 86.379  78.690  90.398  1.00 129.73 ? 297 SER B OG  1 
ATOM   4669 N N   . ALA B 2 309 ? 86.260  79.926  93.346  1.00 119.80 ? 298 ALA B N   1 
ATOM   4670 C CA  . ALA B 2 309 ? 85.542  80.777  94.285  1.00 119.80 ? 298 ALA B CA  1 
ATOM   4671 C C   . ALA B 2 309 ? 86.371  81.000  95.540  1.00 119.80 ? 298 ALA B C   1 
ATOM   4672 O O   . ALA B 2 309 ? 86.615  82.143  95.937  1.00 119.80 ? 298 ALA B O   1 
ATOM   4673 C CB  . ALA B 2 309 ? 84.192  80.156  94.639  1.00 119.80 ? 298 ALA B CB  1 
ATOM   4674 N N   . LYS B 2 310 ? 86.794  79.905  96.172  1.00 118.79 ? 299 LYS B N   1 
ATOM   4675 C CA  . LYS B 2 310 ? 87.654  79.948  97.346  1.00 118.79 ? 299 LYS B CA  1 
ATOM   4676 C C   . LYS B 2 310 ? 88.871  80.830  97.107  1.00 118.79 ? 299 LYS B C   1 
ATOM   4677 O O   . LYS B 2 310 ? 89.237  81.637  97.967  1.00 118.79 ? 299 LYS B O   1 
ATOM   4678 C CB  . LYS B 2 310 ? 88.096  78.535  97.731  1.00 118.79 ? 299 LYS B CB  1 
ATOM   4679 C CG  . LYS B 2 310 ? 88.823  78.458  99.057  1.00 118.79 ? 299 LYS B CG  1 
ATOM   4680 C CD  . LYS B 2 310 ? 87.887  78.785  100.202 1.00 118.79 ? 299 LYS B CD  1 
ATOM   4681 C CE  . LYS B 2 310 ? 86.762  77.771  100.292 1.00 118.79 ? 299 LYS B CE  1 
ATOM   4682 N NZ  . LYS B 2 310 ? 85.874  78.038  101.454 1.00 118.79 ? 299 LYS B NZ  1 
ATOM   4683 N N   . LYS B 2 311 ? 89.507  80.675  95.942  1.00 119.34 ? 300 LYS B N   1 
ATOM   4684 C CA  . LYS B 2 311 ? 90.657  81.507  95.610  1.00 119.34 ? 300 LYS B CA  1 
ATOM   4685 C C   . LYS B 2 311 ? 90.278  82.981  95.581  1.00 119.34 ? 300 LYS B C   1 
ATOM   4686 O O   . LYS B 2 311 ? 91.031  83.833  96.069  1.00 119.34 ? 300 LYS B O   1 
ATOM   4687 C CB  . LYS B 2 311 ? 91.249  81.077  94.266  1.00 119.34 ? 300 LYS B CB  1 
ATOM   4688 C CG  . LYS B 2 311 ? 92.732  81.380  94.124  1.00 119.34 ? 300 LYS B CG  1 
ATOM   4689 C CD  . LYS B 2 311 ? 92.984  82.544  93.181  1.00 119.34 ? 300 LYS B CD  1 
ATOM   4690 C CE  . LYS B 2 311 ? 94.461  82.652  92.841  1.00 119.34 ? 300 LYS B CE  1 
ATOM   4691 N NZ  . LYS B 2 311 ? 94.789  83.949  92.188  1.00 119.34 ? 300 LYS B NZ  1 
ATOM   4692 N N   . LYS B 2 312 ? 89.120  83.306  95.008  1.00 115.26 ? 301 LYS B N   1 
ATOM   4693 C CA  . LYS B 2 312 ? 88.631  84.684  95.049  1.00 115.26 ? 301 LYS B CA  1 
ATOM   4694 C C   . LYS B 2 312 ? 87.697  84.928  96.232  1.00 115.26 ? 301 LYS B C   1 
ATOM   4695 O O   . LYS B 2 312 ? 86.591  85.445  96.066  1.00 115.26 ? 301 LYS B O   1 
ATOM   4696 C CB  . LYS B 2 312 ? 87.956  85.028  93.723  1.00 115.26 ? 301 LYS B CB  1 
ATOM   4697 C CG  . LYS B 2 312 ? 87.600  86.503  93.543  1.00 115.26 ? 301 LYS B CG  1 
ATOM   4698 C CD  . LYS B 2 312 ? 88.829  87.385  93.656  1.00 115.26 ? 301 LYS B CD  1 
ATOM   4699 C CE  . LYS B 2 312 ? 88.539  88.625  94.489  1.00 115.26 ? 301 LYS B CE  1 
ATOM   4700 N NZ  . LYS B 2 312 ? 88.653  88.356  95.951  1.00 115.26 ? 301 LYS B NZ  1 
ATOM   4701 N N   . SER B 2 313 ? 88.125  84.539  97.438  1.00 109.72 ? 302 SER B N   1 
ATOM   4702 C CA  . SER B 2 313 ? 87.497  84.893  98.712  1.00 109.72 ? 302 SER B CA  1 
ATOM   4703 C C   . SER B 2 313 ? 85.972  84.945  98.681  1.00 109.72 ? 302 SER B C   1 
ATOM   4704 O O   . SER B 2 313 ? 85.371  85.855  99.261  1.00 109.72 ? 302 SER B O   1 
ATOM   4705 C CB  . SER B 2 313 ? 88.035  86.241  99.195  1.00 109.72 ? 302 SER B CB  1 
ATOM   4706 O OG  . SER B 2 313 ? 87.193  86.804  100.186 1.00 109.72 ? 302 SER B OG  1 
ATOM   4707 N N   . ILE B 2 314 ? 85.334  83.991  98.011  1.00 106.31 ? 303 ILE B N   1 
ATOM   4708 C CA  . ILE B 2 314 ? 83.881  83.945  97.899  1.00 106.31 ? 303 ILE B CA  1 
ATOM   4709 C C   . ILE B 2 314 ? 83.436  82.532  98.242  1.00 106.31 ? 303 ILE B C   1 
ATOM   4710 O O   . ILE B 2 314 ? 83.530  81.624  97.407  1.00 106.31 ? 303 ILE B O   1 
ATOM   4711 C CB  . ILE B 2 314 ? 83.399  84.361  96.500  1.00 106.31 ? 303 ILE B CB  1 
ATOM   4712 C CG1 . ILE B 2 314 ? 83.494  85.877  96.339  1.00 106.31 ? 303 ILE B CG1 1 
ATOM   4713 C CG2 . ILE B 2 314 ? 81.958  83.939  96.268  1.00 106.31 ? 303 ILE B CG2 1 
ATOM   4714 C CD1 . ILE B 2 314 ? 82.997  86.376  95.004  1.00 106.31 ? 303 ILE B CD1 1 
ATOM   4715 N N   . ARG B 2 315 ? 82.988  82.338  99.476  1.00 102.41 ? 304 ARG B N   1 
ATOM   4716 C CA  . ARG B 2 315 ? 82.487  81.046  99.912  1.00 102.41 ? 304 ARG B CA  1 
ATOM   4717 C C   . ARG B 2 315 ? 81.183  80.730  99.195  1.00 102.41 ? 304 ARG B C   1 
ATOM   4718 O O   . ARG B 2 315 ? 80.424  81.628  98.827  1.00 102.41 ? 304 ARG B O   1 
ATOM   4719 C CB  . ARG B 2 315 ? 82.281  81.030  101.425 1.00 102.41 ? 304 ARG B CB  1 
ATOM   4720 C CG  . ARG B 2 315 ? 83.576  80.927  102.210 1.00 102.41 ? 304 ARG B CG  1 
ATOM   4721 C CD  . ARG B 2 315 ? 84.114  82.303  102.559 1.00 102.41 ? 304 ARG B CD  1 
ATOM   4722 N NE  . ARG B 2 315 ? 85.350  82.233  103.331 1.00 102.41 ? 304 ARG B NE  1 
ATOM   4723 C CZ  . ARG B 2 315 ? 85.955  83.289  103.863 1.00 102.41 ? 304 ARG B CZ  1 
ATOM   4724 N NH1 . ARG B 2 315 ? 85.437  84.500  103.708 1.00 102.41 ? 304 ARG B NH1 1 
ATOM   4725 N NH2 . ARG B 2 315 ? 87.078  83.136  104.550 1.00 102.41 ? 304 ARG B NH2 1 
ATOM   4726 N N   . VAL B 2 316 ? 80.929  79.442  98.998  1.00 103.36 ? 305 VAL B N   1 
ATOM   4727 C CA  . VAL B 2 316 ? 79.819  78.978  98.178  1.00 103.36 ? 305 VAL B CA  1 
ATOM   4728 C C   . VAL B 2 316 ? 78.874  78.161  99.045  1.00 103.36 ? 305 VAL B C   1 
ATOM   4729 O O   . VAL B 2 316 ? 79.318  77.356  99.870  1.00 103.36 ? 305 VAL B O   1 
ATOM   4730 C CB  . VAL B 2 316 ? 80.318  78.154  96.978  1.00 103.36 ? 305 VAL B CB  1 
ATOM   4731 C CG1 . VAL B 2 316 ? 79.184  77.372  96.344  1.00 103.36 ? 305 VAL B CG1 1 
ATOM   4732 C CG2 . VAL B 2 316 ? 80.967  79.064  95.959  1.00 103.36 ? 305 VAL B CG2 1 
ATOM   4733 N N   . ILE B 2 317 ? 77.578  78.370  98.854  1.00 106.60 ? 306 ILE B N   1 
ATOM   4734 C CA  . ILE B 2 317 ? 76.545  77.601  99.517  1.00 106.60 ? 306 ILE B CA  1 
ATOM   4735 C C   . ILE B 2 317 ? 75.853  76.770  98.446  1.00 106.60 ? 306 ILE B C   1 
ATOM   4736 O O   . ILE B 2 317 ? 76.164  76.861  97.257  1.00 106.60 ? 306 ILE B O   1 
ATOM   4737 C CB  . ILE B 2 317 ? 75.552  78.520  100.271 1.00 106.60 ? 306 ILE B CB  1 
ATOM   4738 C CG1 . ILE B 2 317 ? 76.314  79.592  101.048 1.00 106.60 ? 306 ILE B CG1 1 
ATOM   4739 C CG2 . ILE B 2 317 ? 74.701  77.748  101.255 1.00 106.60 ? 306 ILE B CG2 1 
ATOM   4740 C CD1 . ILE B 2 317 ? 75.439  80.408  101.967 1.00 106.60 ? 306 ILE B CD1 1 
ATOM   4741 N N   . LEU B 2 318 ? 74.918  75.928  98.863  1.00 121.36 ? 307 LEU B N   1 
ATOM   4742 C CA  . LEU B 2 318 ? 74.214  75.049  97.946  1.00 121.36 ? 307 LEU B CA  1 
ATOM   4743 C C   . LEU B 2 318 ? 72.806  74.831  98.473  1.00 121.36 ? 307 LEU B C   1 
ATOM   4744 O O   . LEU B 2 318 ? 72.593  74.765  99.686  1.00 121.36 ? 307 LEU B O   1 
ATOM   4745 C CB  . LEU B 2 318 ? 74.964  73.719  97.799  1.00 121.36 ? 307 LEU B CB  1 
ATOM   4746 C CG  . LEU B 2 318 ? 74.902  72.905  96.504  1.00 121.36 ? 307 LEU B CG  1 
ATOM   4747 C CD1 . LEU B 2 318 ? 75.917  71.777  96.563  1.00 121.36 ? 307 LEU B CD1 1 
ATOM   4748 C CD2 . LEU B 2 318 ? 73.523  72.343  96.243  1.00 121.36 ? 307 LEU B CD2 1 
ATOM   4749 N N   . ASP B 2 319 ? 71.846  74.732  97.561  1.00 131.65 ? 308 ASP B N   1 
ATOM   4750 C CA  . ASP B 2 319 ? 70.450  74.544  97.928  1.00 131.65 ? 308 ASP B CA  1 
ATOM   4751 C C   . ASP B 2 319 ? 70.102  73.065  97.852  1.00 131.65 ? 308 ASP B C   1 
ATOM   4752 O O   . ASP B 2 319 ? 70.389  72.404  96.849  1.00 131.65 ? 308 ASP B O   1 
ATOM   4753 C CB  . ASP B 2 319 ? 69.537  75.355  97.008  1.00 131.65 ? 308 ASP B CB  1 
ATOM   4754 C CG  . ASP B 2 319 ? 68.154  75.573  97.597  1.00 131.65 ? 308 ASP B CG  1 
ATOM   4755 O OD1 . ASP B 2 319 ? 67.628  74.650  98.255  1.00 131.65 ? 308 ASP B OD1 1 
ATOM   4756 O OD2 . ASP B 2 319 ? 67.592  76.672  97.399  1.00 131.65 ? 308 ASP B OD2 1 
ATOM   4757 N N   . LEU B 2 320 ? 69.473  72.554  98.903  1.00 141.44 ? 309 LEU B N   1 
ATOM   4758 C CA  . LEU B 2 320 ? 69.139  71.141  99.005  1.00 141.44 ? 309 LEU B CA  1 
ATOM   4759 C C   . LEU B 2 320 ? 67.635  70.938  99.120  1.00 141.44 ? 309 LEU B C   1 
ATOM   4760 O O   . LEU B 2 320 ? 67.165  70.000  99.767  1.00 141.44 ? 309 LEU B O   1 
ATOM   4761 C CB  . LEU B 2 320 ? 69.852  70.487  100.187 1.00 141.44 ? 309 LEU B CB  1 
ATOM   4762 C CG  . LEU B 2 320 ? 71.209  69.816  99.957  1.00 141.44 ? 309 LEU B CG  1 
ATOM   4763 C CD1 . LEU B 2 320 ? 72.152  70.684  99.147  1.00 141.44 ? 309 LEU B CD1 1 
ATOM   4764 C CD2 . LEU B 2 320 ? 71.836  69.412  101.281 1.00 141.44 ? 309 LEU B CD2 1 
ATOM   4765 N N   . THR B 2 321 ? 66.858  71.813  98.497  1.00 149.40 ? 310 THR B N   1 
ATOM   4766 C CA  . THR B 2 321 ? 65.428  71.559  98.427  1.00 149.40 ? 310 THR B CA  1 
ATOM   4767 C C   . THR B 2 321 ? 65.200  70.463  97.394  1.00 149.40 ? 310 THR B C   1 
ATOM   4768 O O   . THR B 2 321 ? 65.471  70.665  96.204  1.00 149.40 ? 310 THR B O   1 
ATOM   4769 C CB  . THR B 2 321 ? 64.657  72.826  98.062  1.00 149.40 ? 310 THR B CB  1 
ATOM   4770 O OG1 . THR B 2 321 ? 65.048  73.893  98.935  1.00 149.40 ? 310 THR B OG1 1 
ATOM   4771 C CG2 . THR B 2 321 ? 63.165  72.591  98.207  1.00 149.40 ? 310 THR B CG2 1 
ATOM   4772 N N   . PRO B 2 322 ? 64.715  69.291  97.807  1.00 158.74 ? 311 PRO B N   1 
ATOM   4773 C CA  . PRO B 2 322 ? 64.660  68.146  96.887  1.00 158.74 ? 311 PRO B CA  1 
ATOM   4774 C C   . PRO B 2 322 ? 63.726  68.361  95.708  1.00 158.74 ? 311 PRO B C   1 
ATOM   4775 O O   . PRO B 2 322 ? 64.142  68.261  94.550  1.00 158.74 ? 311 PRO B O   1 
ATOM   4776 C CB  . PRO B 2 322 ? 64.172  66.993  97.779  1.00 158.74 ? 311 PRO B CB  1 
ATOM   4777 C CG  . PRO B 2 322 ? 64.226  67.508  99.190  1.00 158.74 ? 311 PRO B CG  1 
ATOM   4778 C CD  . PRO B 2 322 ? 64.097  68.989  99.105  1.00 158.74 ? 311 PRO B CD  1 
ATOM   4779 N N   . ASN B 2 323 ? 62.461  68.669  95.992  1.00 161.43 ? 312 ASN B N   1 
ATOM   4780 C CA  . ASN B 2 323 ? 61.443  68.771  94.948  1.00 161.43 ? 312 ASN B CA  1 
ATOM   4781 C C   . ASN B 2 323 ? 61.318  70.223  94.484  1.00 161.43 ? 312 ASN B C   1 
ATOM   4782 O O   . ASN B 2 323 ? 60.288  70.881  94.636  1.00 161.43 ? 312 ASN B O   1 
ATOM   4783 C CB  . ASN B 2 323 ? 60.113  68.224  95.449  1.00 161.43 ? 312 ASN B CB  1 
ATOM   4784 C CG  . ASN B 2 323 ? 59.134  67.958  94.325  1.00 161.43 ? 312 ASN B CG  1 
ATOM   4785 O OD1 . ASN B 2 323 ? 59.508  67.934  93.153  1.00 161.43 ? 312 ASN B OD1 1 
ATOM   4786 N ND2 . ASN B 2 323 ? 57.870  67.754  94.678  1.00 161.43 ? 312 ASN B ND2 1 
ATOM   4787 N N   . TYR B 2 324 ? 62.404  70.718  93.897  1.00 157.28 ? 313 TYR B N   1 
ATOM   4788 C CA  . TYR B 2 324 ? 62.425  72.074  93.368  1.00 157.28 ? 313 TYR B CA  1 
ATOM   4789 C C   . TYR B 2 324 ? 61.834  72.170  91.967  1.00 157.28 ? 313 TYR B C   1 
ATOM   4790 O O   . TYR B 2 324 ? 61.835  73.258  91.383  1.00 157.28 ? 313 TYR B O   1 
ATOM   4791 C CB  . TYR B 2 324 ? 63.853  72.628  93.377  1.00 157.28 ? 313 TYR B CB  1 
ATOM   4792 C CG  . TYR B 2 324 ? 64.736  72.144  92.250  1.00 157.28 ? 313 TYR B CG  1 
ATOM   4793 C CD1 . TYR B 2 324 ? 65.236  70.850  92.238  1.00 157.28 ? 313 TYR B CD1 1 
ATOM   4794 C CD2 . TYR B 2 324 ? 65.084  72.990  91.207  1.00 157.28 ? 313 TYR B CD2 1 
ATOM   4795 C CE1 . TYR B 2 324 ? 66.052  70.411  91.214  1.00 157.28 ? 313 TYR B CE1 1 
ATOM   4796 C CE2 . TYR B 2 324 ? 65.897  72.559  90.178  1.00 157.28 ? 313 TYR B CE2 1 
ATOM   4797 C CZ  . TYR B 2 324 ? 66.378  71.269  90.186  1.00 157.28 ? 313 TYR B CZ  1 
ATOM   4798 O OH  . TYR B 2 324 ? 67.189  70.836  89.162  1.00 157.28 ? 313 TYR B OH  1 
ATOM   4799 N N   . ARG B 2 325 ? 61.333  71.065  91.420  1.00 159.98 ? 314 ARG B N   1 
ATOM   4800 C CA  . ARG B 2 325 ? 60.536  71.058  90.194  1.00 159.98 ? 314 ARG B CA  1 
ATOM   4801 C C   . ARG B 2 325 ? 59.198  70.421  90.551  1.00 159.98 ? 314 ARG B C   1 
ATOM   4802 O O   . ARG B 2 325 ? 59.003  69.213  90.394  1.00 159.98 ? 314 ARG B O   1 
ATOM   4803 C CB  . ARG B 2 325 ? 61.233  70.313  89.062  1.00 159.98 ? 314 ARG B CB  1 
ATOM   4804 C CG  . ARG B 2 325 ? 62.623  70.820  88.736  1.00 159.98 ? 314 ARG B CG  1 
ATOM   4805 C CD  . ARG B 2 325 ? 63.217  70.032  87.585  1.00 159.98 ? 314 ARG B CD  1 
ATOM   4806 N NE  . ARG B 2 325 ? 64.658  70.222  87.468  1.00 159.98 ? 314 ARG B NE  1 
ATOM   4807 C CZ  . ARG B 2 325 ? 65.235  71.022  86.579  1.00 159.98 ? 314 ARG B CZ  1 
ATOM   4808 N NH1 . ARG B 2 325 ? 64.492  71.710  85.723  1.00 159.98 ? 314 ARG B NH1 1 
ATOM   4809 N NH2 . ARG B 2 325 ? 66.556  71.133  86.543  1.00 159.98 ? 314 ARG B NH2 1 
ATOM   4810 N N   . GLY B 2 326 ? 58.280  71.240  91.033  1.00 160.46 ? 315 GLY B N   1 
ATOM   4811 C CA  . GLY B 2 326 ? 57.001  70.763  91.511  1.00 160.46 ? 315 GLY B CA  1 
ATOM   4812 C C   . GLY B 2 326 ? 56.442  71.686  92.564  1.00 160.46 ? 315 GLY B C   1 
ATOM   4813 O O   . GLY B 2 326 ? 57.167  72.423  93.236  1.00 160.46 ? 315 GLY B O   1 
ATOM   4814 N N   . GLU B 2 327 ? 55.113  71.652  92.694  1.00 162.27 ? 316 GLU B N   1 
ATOM   4815 C CA  . GLU B 2 327 ? 54.441  72.514  93.662  1.00 162.27 ? 316 GLU B CA  1 
ATOM   4816 C C   . GLU B 2 327 ? 54.965  72.267  95.071  1.00 162.27 ? 316 GLU B C   1 
ATOM   4817 O O   . GLU B 2 327 ? 55.549  73.164  95.691  1.00 162.27 ? 316 GLU B O   1 
ATOM   4818 C CB  . GLU B 2 327 ? 52.927  72.296  93.592  1.00 162.27 ? 316 GLU B CB  1 
ATOM   4819 C CG  . GLU B 2 327 ? 52.087  73.234  94.460  1.00 162.27 ? 316 GLU B CG  1 
ATOM   4820 C CD  . GLU B 2 327 ? 52.059  72.839  95.925  1.00 162.27 ? 316 GLU B CD  1 
ATOM   4821 O OE1 . GLU B 2 327 ? 52.156  71.629  96.220  1.00 162.27 ? 316 GLU B OE1 1 
ATOM   4822 O OE2 . GLU B 2 327 ? 51.941  73.740  96.782  1.00 162.27 ? 316 GLU B OE2 1 
ATOM   4823 N N   . ASN B 2 328 ? 54.772  71.059  95.593  1.00 161.77 ? 317 ASN B N   1 
ATOM   4824 C CA  . ASN B 2 328 ? 55.324  70.704  96.892  1.00 161.77 ? 317 ASN B CA  1 
ATOM   4825 C C   . ASN B 2 328 ? 56.829  70.514  96.767  1.00 161.77 ? 317 ASN B C   1 
ATOM   4826 O O   . ASN B 2 328 ? 57.304  69.830  95.855  1.00 161.77 ? 317 ASN B O   1 
ATOM   4827 C CB  . ASN B 2 328 ? 54.668  69.433  97.428  1.00 161.77 ? 317 ASN B CB  1 
ATOM   4828 C CG  . ASN B 2 328 ? 54.994  69.184  98.884  1.00 161.77 ? 317 ASN B CG  1 
ATOM   4829 O OD1 . ASN B 2 328 ? 56.012  68.574  99.211  1.00 161.77 ? 317 ASN B OD1 1 
ATOM   4830 N ND2 . ASN B 2 328 ? 54.129  69.659  99.772  1.00 161.77 ? 317 ASN B ND2 1 
ATOM   4831 N N   . SER B 2 329 ? 57.579  71.122  97.684  1.00 158.04 ? 318 SER B N   1 
ATOM   4832 C CA  . SER B 2 329 ? 59.031  71.144  97.592  1.00 158.04 ? 318 SER B CA  1 
ATOM   4833 C C   . SER B 2 329 ? 59.716  70.069  98.422  1.00 158.04 ? 318 SER B C   1 
ATOM   4834 O O   . SER B 2 329 ? 60.902  69.803  98.201  1.00 158.04 ? 318 SER B O   1 
ATOM   4835 C CB  . SER B 2 329 ? 59.563  72.518  98.017  1.00 158.04 ? 318 SER B CB  1 
ATOM   4836 O OG  . SER B 2 329 ? 59.303  72.762  99.388  1.00 158.04 ? 318 SER B OG  1 
ATOM   4837 N N   . TRP B 2 330 ? 59.008  69.446  99.365  1.00 157.49 ? 319 TRP B N   1 
ATOM   4838 C CA  . TRP B 2 330 ? 59.612  68.500  100.293 1.00 157.49 ? 319 TRP B CA  1 
ATOM   4839 C C   . TRP B 2 330 ? 59.180  67.061  100.040 1.00 157.49 ? 319 TRP B C   1 
ATOM   4840 O O   . TRP B 2 330 ? 59.394  66.201  100.902 1.00 157.49 ? 319 TRP B O   1 
ATOM   4841 C CB  . TRP B 2 330 ? 59.282  68.891  101.732 1.00 157.49 ? 319 TRP B CB  1 
ATOM   4842 C CG  . TRP B 2 330 ? 60.130  69.992  102.263 1.00 157.49 ? 319 TRP B CG  1 
ATOM   4843 C CD1 . TRP B 2 330 ? 59.710  71.220  102.667 1.00 157.49 ? 319 TRP B CD1 1 
ATOM   4844 C CD2 . TRP B 2 330 ? 61.548  69.968  102.454 1.00 157.49 ? 319 TRP B CD2 1 
ATOM   4845 N NE1 . TRP B 2 330 ? 60.777  71.967  103.100 1.00 157.49 ? 319 TRP B NE1 1 
ATOM   4846 C CE2 . TRP B 2 330 ? 61.918  71.220  102.979 1.00 157.49 ? 319 TRP B CE2 1 
ATOM   4847 C CE3 . TRP B 2 330 ? 62.541  69.009  102.233 1.00 157.49 ? 319 TRP B CE3 1 
ATOM   4848 C CZ2 . TRP B 2 330 ? 63.237  71.538  103.286 1.00 157.49 ? 319 TRP B CZ2 1 
ATOM   4849 C CZ3 . TRP B 2 330 ? 63.849  69.328  102.540 1.00 157.49 ? 319 TRP B CZ3 1 
ATOM   4850 C CH2 . TRP B 2 330 ? 64.185  70.581  103.058 1.00 157.49 ? 319 TRP B CH2 1 
ATOM   4851 N N   . PHE B 2 331 ? 58.579  66.779  98.885  1.00 167.57 ? 320 PHE B N   1 
ATOM   4852 C CA  . PHE B 2 331 ? 58.060  65.448  98.573  1.00 167.57 ? 320 PHE B CA  1 
ATOM   4853 C C   . PHE B 2 331 ? 57.057  65.007  99.640  1.00 167.57 ? 320 PHE B C   1 
ATOM   4854 O O   . PHE B 2 331 ? 57.288  64.067  100.403 1.00 167.57 ? 320 PHE B O   1 
ATOM   4855 C CB  . PHE B 2 331 ? 59.196  64.431  98.421  1.00 167.57 ? 320 PHE B CB  1 
ATOM   4856 C CG  . PHE B 2 331 ? 59.966  64.567  97.140  1.00 167.57 ? 320 PHE B CG  1 
ATOM   4857 C CD1 . PHE B 2 331 ? 59.308  64.635  95.923  1.00 167.57 ? 320 PHE B CD1 1 
ATOM   4858 C CD2 . PHE B 2 331 ? 61.350  64.614  97.150  1.00 167.57 ? 320 PHE B CD2 1 
ATOM   4859 C CE1 . PHE B 2 331 ? 60.016  64.754  94.742  1.00 167.57 ? 320 PHE B CE1 1 
ATOM   4860 C CE2 . PHE B 2 331 ? 62.063  64.734  95.972  1.00 167.57 ? 320 PHE B CE2 1 
ATOM   4861 C CZ  . PHE B 2 331 ? 61.394  64.805  94.767  1.00 167.57 ? 320 PHE B CZ  1 
ATOM   4862 N N   . SER B 2 332 ? 55.930  65.728  99.680  1.00 169.70 ? 321 SER B N   1 
ATOM   4863 C CA  . SER B 2 332 ? 54.955  65.605  100.764 1.00 169.70 ? 321 SER B CA  1 
ATOM   4864 C C   . SER B 2 332 ? 54.586  64.162  101.090 1.00 169.70 ? 321 SER B C   1 
ATOM   4865 O O   . SER B 2 332 ? 54.133  63.878  102.206 1.00 169.70 ? 321 SER B O   1 
ATOM   4866 C CB  . SER B 2 332 ? 53.690  66.388  100.412 1.00 169.70 ? 321 SER B CB  1 
ATOM   4867 O OG  . SER B 2 332 ? 52.791  65.588  99.664  1.00 169.70 ? 321 SER B OG  1 
ATOM   4868 N N   . THR B 2 333 ? 54.753  63.243  100.136 1.00 173.92 ? 322 THR B N   1 
ATOM   4869 C CA  . THR B 2 333 ? 54.378  61.851  100.370 1.00 173.92 ? 322 THR B CA  1 
ATOM   4870 C C   . THR B 2 333 ? 55.128  61.253  101.555 1.00 173.92 ? 322 THR B C   1 
ATOM   4871 O O   . THR B 2 333 ? 54.536  60.546  102.380 1.00 173.92 ? 322 THR B O   1 
ATOM   4872 C CB  . THR B 2 333 ? 54.629  61.020  99.110  1.00 173.92 ? 322 THR B CB  1 
ATOM   4873 O OG1 . THR B 2 333 ? 55.880  61.401  98.524  1.00 173.92 ? 322 THR B OG1 1 
ATOM   4874 C CG2 . THR B 2 333 ? 53.514  61.236  98.099  1.00 173.92 ? 322 THR B CG2 1 
ATOM   4875 N N   . GLN B 2 334 ? 56.427  61.527  101.663 1.00 173.52 ? 323 GLN B N   1 
ATOM   4876 C CA  . GLN B 2 334 ? 57.254  60.916  102.694 1.00 173.52 ? 323 GLN B CA  1 
ATOM   4877 C C   . GLN B 2 334 ? 58.181  61.965  103.292 1.00 173.52 ? 323 GLN B C   1 
ATOM   4878 O O   . GLN B 2 334 ? 58.539  62.945  102.634 1.00 173.52 ? 323 GLN B O   1 
ATOM   4879 C CB  . GLN B 2 334 ? 58.063  59.741  102.125 1.00 173.52 ? 323 GLN B CB  1 
ATOM   4880 C CG  . GLN B 2 334 ? 58.813  58.937  103.165 1.00 173.52 ? 323 GLN B CG  1 
ATOM   4881 C CD  . GLN B 2 334 ? 57.976  58.662  104.399 1.00 173.52 ? 323 GLN B CD  1 
ATOM   4882 O OE1 . GLN B 2 334 ? 58.230  59.211  105.471 1.00 173.52 ? 323 GLN B OE1 1 
ATOM   4883 N NE2 . GLN B 2 334 ? 56.971  57.807  104.253 1.00 173.52 ? 323 GLN B NE2 1 
ATOM   4884 N N   . VAL B 2 335 ? 58.566  61.751  104.549 1.00 170.16 ? 324 VAL B N   1 
ATOM   4885 C CA  . VAL B 2 335 ? 59.393  62.706  105.278 1.00 170.16 ? 324 VAL B CA  1 
ATOM   4886 C C   . VAL B 2 335 ? 60.650  62.083  105.871 1.00 170.16 ? 324 VAL B C   1 
ATOM   4887 O O   . VAL B 2 335 ? 61.603  62.820  106.168 1.00 170.16 ? 324 VAL B O   1 
ATOM   4888 C CB  . VAL B 2 335 ? 58.584  63.414  106.389 1.00 170.16 ? 324 VAL B CB  1 
ATOM   4889 C CG1 . VAL B 2 335 ? 58.430  62.511  107.606 1.00 170.16 ? 324 VAL B CG1 1 
ATOM   4890 C CG2 . VAL B 2 335 ? 59.222  64.747  106.765 1.00 170.16 ? 324 VAL B CG2 1 
ATOM   4891 N N   . ASP B 2 336 ? 60.705  60.762  106.048 1.00 170.40 ? 325 ASP B N   1 
ATOM   4892 C CA  . ASP B 2 336 ? 61.830  60.142  106.761 1.00 170.40 ? 325 ASP B CA  1 
ATOM   4893 C C   . ASP B 2 336 ? 63.006  59.886  105.821 1.00 170.40 ? 325 ASP B C   1 
ATOM   4894 O O   . ASP B 2 336 ? 64.151  60.211  106.147 1.00 170.40 ? 325 ASP B O   1 
ATOM   4895 C CB  . ASP B 2 336 ? 61.372  58.863  107.471 1.00 170.40 ? 325 ASP B CB  1 
ATOM   4896 C CG  . ASP B 2 336 ? 61.157  57.699  106.522 1.00 170.40 ? 325 ASP B CG  1 
ATOM   4897 O OD1 . ASP B 2 336 ? 60.827  57.936  105.343 1.00 170.40 ? 325 ASP B OD1 1 
ATOM   4898 O OD2 . ASP B 2 336 ? 61.317  56.540  106.959 1.00 170.40 ? 325 ASP B OD2 1 
ATOM   4899 N N   . THR B 2 337 ? 62.738  59.306  104.648 1.00 167.56 ? 326 THR B N   1 
ATOM   4900 C CA  . THR B 2 337 ? 63.825  58.973  103.733 1.00 167.56 ? 326 THR B CA  1 
ATOM   4901 C C   . THR B 2 337 ? 64.416  60.219  103.085 1.00 167.56 ? 326 THR B C   1 
ATOM   4902 O O   . THR B 2 337 ? 65.615  60.253  102.780 1.00 167.56 ? 326 THR B O   1 
ATOM   4903 C CB  . THR B 2 337 ? 63.338  57.987  102.666 1.00 167.56 ? 326 THR B CB  1 
ATOM   4904 O OG1 . THR B 2 337 ? 64.395  57.725  101.736 1.00 167.56 ? 326 THR B OG1 1 
ATOM   4905 C CG2 . THR B 2 337 ? 62.137  58.543  101.918 1.00 167.56 ? 326 THR B CG2 1 
ATOM   4906 N N   . VAL B 2 338 ? 63.599  61.254  102.874 1.00 164.73 ? 327 VAL B N   1 
ATOM   4907 C CA  . VAL B 2 338 ? 64.135  62.522  102.392 1.00 164.73 ? 327 VAL B CA  1 
ATOM   4908 C C   . VAL B 2 338 ? 65.062  63.130  103.436 1.00 164.73 ? 327 VAL B C   1 
ATOM   4909 O O   . VAL B 2 338 ? 66.071  63.766  103.101 1.00 164.73 ? 327 VAL B O   1 
ATOM   4910 C CB  . VAL B 2 338 ? 62.990  63.476  101.997 1.00 164.73 ? 327 VAL B CB  1 
ATOM   4911 C CG1 . VAL B 2 338 ? 62.018  62.770  101.065 1.00 164.73 ? 327 VAL B CG1 1 
ATOM   4912 C CG2 . VAL B 2 338 ? 62.255  64.000  103.222 1.00 164.73 ? 327 VAL B CG2 1 
ATOM   4913 N N   . ALA B 2 339 ? 64.754  62.920  104.718 1.00 161.77 ? 328 ALA B N   1 
ATOM   4914 C CA  . ALA B 2 339 ? 65.669  63.346  105.768 1.00 161.77 ? 328 ALA B CA  1 
ATOM   4915 C C   . ALA B 2 339 ? 66.991  62.601  105.670 1.00 161.77 ? 328 ALA B C   1 
ATOM   4916 O O   . ALA B 2 339 ? 68.050  63.186  105.902 1.00 161.77 ? 328 ALA B O   1 
ATOM   4917 C CB  . ALA B 2 339 ? 65.031  63.141  107.141 1.00 161.77 ? 328 ALA B CB  1 
ATOM   4918 N N   . THR B 2 340 ? 66.954  61.318  105.301 1.00 161.12 ? 329 THR B N   1 
ATOM   4919 C CA  . THR B 2 340 ? 68.192  60.561  105.129 1.00 161.12 ? 329 THR B CA  1 
ATOM   4920 C C   . THR B 2 340 ? 68.993  61.067  103.935 1.00 161.12 ? 329 THR B C   1 
ATOM   4921 O O   . THR B 2 340 ? 70.230  61.138  103.993 1.00 161.12 ? 329 THR B O   1 
ATOM   4922 C CB  . THR B 2 340 ? 67.885  59.072  104.969 1.00 161.12 ? 329 THR B CB  1 
ATOM   4923 O OG1 . THR B 2 340 ? 67.351  58.829  103.661 1.00 161.12 ? 329 THR B OG1 1 
ATOM   4924 C CG2 . THR B 2 340 ? 66.885  58.616  106.017 1.00 161.12 ? 329 THR B CG2 1 
ATOM   4925 N N   . LYS B 2 341 ? 68.311  61.388  102.831 1.00 161.75 ? 330 LYS B N   1 
ATOM   4926 C CA  . LYS B 2 341 ? 69.007  61.962  101.683 1.00 161.75 ? 330 LYS B CA  1 
ATOM   4927 C C   . LYS B 2 341 ? 69.682  63.273  102.060 1.00 161.75 ? 330 LYS B C   1 
ATOM   4928 O O   . LYS B 2 341 ? 70.844  63.509  101.711 1.00 161.75 ? 330 LYS B O   1 
ATOM   4929 C CB  . LYS B 2 341 ? 68.050  62.171  100.508 1.00 161.75 ? 330 LYS B CB  1 
ATOM   4930 C CG  . LYS B 2 341 ? 67.376  60.914  99.986  1.00 161.75 ? 330 LYS B CG  1 
ATOM   4931 C CD  . LYS B 2 341 ? 65.920  61.180  99.649  1.00 161.75 ? 330 LYS B CD  1 
ATOM   4932 C CE  . LYS B 2 341 ? 65.117  59.896  99.574  1.00 161.75 ? 330 LYS B CE  1 
ATOM   4933 N NZ  . LYS B 2 341 ? 63.661  60.165  99.417  1.00 161.75 ? 330 LYS B NZ  1 
ATOM   4934 N N   . VAL B 2 342 ? 68.971  64.140  102.783 1.00 155.71 ? 331 VAL B N   1 
ATOM   4935 C CA  . VAL B 2 342 ? 69.596  65.375  103.249 1.00 155.71 ? 331 VAL B CA  1 
ATOM   4936 C C   . VAL B 2 342 ? 70.770  65.059  104.166 1.00 155.71 ? 331 VAL B C   1 
ATOM   4937 O O   . VAL B 2 342 ? 71.839  65.673  104.066 1.00 155.71 ? 331 VAL B O   1 
ATOM   4938 C CB  . VAL B 2 342 ? 68.560  66.278  103.943 1.00 155.71 ? 331 VAL B CB  1 
ATOM   4939 C CG1 . VAL B 2 342 ? 69.226  67.545  104.451 1.00 155.71 ? 331 VAL B CG1 1 
ATOM   4940 C CG2 . VAL B 2 342 ? 67.437  66.624  102.982 1.00 155.71 ? 331 VAL B CG2 1 
ATOM   4941 N N   . LYS B 2 343 ? 70.594  64.082  105.059 1.00 153.66 ? 332 LYS B N   1 
ATOM   4942 C CA  . LYS B 2 343 ? 71.638  63.697  106.002 1.00 153.66 ? 332 LYS B CA  1 
ATOM   4943 C C   . LYS B 2 343 ? 72.939  63.375  105.283 1.00 153.66 ? 332 LYS B C   1 
ATOM   4944 O O   . LYS B 2 343 ? 73.972  64.009  105.525 1.00 153.66 ? 332 LYS B O   1 
ATOM   4945 C CB  . LYS B 2 343 ? 71.174  62.491  106.821 1.00 153.66 ? 332 LYS B CB  1 
ATOM   4946 C CG  . LYS B 2 343 ? 70.340  62.822  108.043 1.00 153.66 ? 332 LYS B CG  1 
ATOM   4947 C CD  . LYS B 2 343 ? 70.164  61.590  108.916 1.00 153.66 ? 332 LYS B CD  1 
ATOM   4948 C CE  . LYS B 2 343 ? 68.927  61.700  109.792 1.00 153.66 ? 332 LYS B CE  1 
ATOM   4949 N NZ  . LYS B 2 343 ? 69.239  61.462  111.228 1.00 153.66 ? 332 LYS B NZ  1 
ATOM   4950 N N   . ASP B 2 344 ? 72.909  62.385  104.388 1.00 152.70 ? 333 ASP B N   1 
ATOM   4951 C CA  . ASP B 2 344 ? 74.168  61.982  103.769 1.00 152.70 ? 333 ASP B CA  1 
ATOM   4952 C C   . ASP B 2 344 ? 74.640  63.006  102.743 1.00 152.70 ? 333 ASP B C   1 
ATOM   4953 O O   . ASP B 2 344 ? 75.850  63.141  102.522 1.00 152.70 ? 333 ASP B O   1 
ATOM   4954 C CB  . ASP B 2 344 ? 74.070  60.586  103.141 1.00 152.70 ? 333 ASP B CB  1 
ATOM   4955 C CG  . ASP B 2 344 ? 73.017  60.491  102.065 1.00 152.70 ? 333 ASP B CG  1 
ATOM   4956 O OD1 . ASP B 2 344 ? 72.096  61.319  102.060 1.00 152.70 ? 333 ASP B OD1 1 
ATOM   4957 O OD2 . ASP B 2 344 ? 73.115  59.581  101.215 1.00 152.70 ? 333 ASP B OD2 1 
ATOM   4958 N N   . ALA B 2 345 ? 73.721  63.762  102.131 1.00 151.18 ? 334 ALA B N   1 
ATOM   4959 C CA  . ALA B 2 345 ? 74.142  64.784  101.184 1.00 151.18 ? 334 ALA B CA  1 
ATOM   4960 C C   . ALA B 2 345 ? 74.914  65.902  101.868 1.00 151.18 ? 334 ALA B C   1 
ATOM   4961 O O   . ALA B 2 345 ? 75.873  66.424  101.291 1.00 151.18 ? 334 ALA B O   1 
ATOM   4962 C CB  . ALA B 2 345 ? 72.929  65.351  100.450 1.00 151.18 ? 334 ALA B CB  1 
ATOM   4963 N N   . LEU B 2 346 ? 74.515  66.286  103.083 1.00 145.63 ? 335 LEU B N   1 
ATOM   4964 C CA  . LEU B 2 346 ? 75.261  67.305  103.816 1.00 145.63 ? 335 LEU B CA  1 
ATOM   4965 C C   . LEU B 2 346 ? 76.732  66.927  103.922 1.00 145.63 ? 335 LEU B C   1 
ATOM   4966 O O   . LEU B 2 346 ? 77.615  67.681  103.495 1.00 145.63 ? 335 LEU B O   1 
ATOM   4967 C CB  . LEU B 2 346 ? 74.660  67.514  105.208 1.00 145.63 ? 335 LEU B CB  1 
ATOM   4968 C CG  . LEU B 2 346 ? 73.228  68.032  105.338 1.00 145.63 ? 335 LEU B CG  1 
ATOM   4969 C CD1 . LEU B 2 346 ? 72.607  67.526  106.627 1.00 145.63 ? 335 LEU B CD1 1 
ATOM   4970 C CD2 . LEU B 2 346 ? 73.184  69.546  105.289 1.00 145.63 ? 335 LEU B CD2 1 
ATOM   4971 N N   . GLU B 2 347 ? 77.013  65.743  104.471 1.00 150.44 ? 336 GLU B N   1 
ATOM   4972 C CA  . GLU B 2 347 ? 78.401  65.347  104.680 1.00 150.44 ? 336 GLU B CA  1 
ATOM   4973 C C   . GLU B 2 347 ? 79.114  65.097  103.357 1.00 150.44 ? 336 GLU B C   1 
ATOM   4974 O O   . GLU B 2 347 ? 80.304  65.409  103.226 1.00 150.44 ? 336 GLU B O   1 
ATOM   4975 C CB  . GLU B 2 347 ? 78.471  64.121  105.597 1.00 150.44 ? 336 GLU B CB  1 
ATOM   4976 C CG  . GLU B 2 347 ? 77.605  62.929  105.203 1.00 150.44 ? 336 GLU B CG  1 
ATOM   4977 C CD  . GLU B 2 347 ? 78.258  62.041  104.160 1.00 150.44 ? 336 GLU B CD  1 
ATOM   4978 O OE1 . GLU B 2 347 ? 77.540  61.249  103.515 1.00 150.44 ? 336 GLU B OE1 1 
ATOM   4979 O OE2 . GLU B 2 347 ? 79.492  62.129  103.990 1.00 150.44 ? 336 GLU B OE2 1 
ATOM   4980 N N   . PHE B 2 348 ? 78.406  64.571  102.352 1.00 149.25 ? 337 PHE B N   1 
ATOM   4981 C CA  . PHE B 2 348 ? 79.044  64.334  101.060 1.00 149.25 ? 337 PHE B CA  1 
ATOM   4982 C C   . PHE B 2 348 ? 79.499  65.643  100.428 1.00 149.25 ? 337 PHE B C   1 
ATOM   4983 O O   . PHE B 2 348 ? 80.664  65.788  100.039 1.00 149.25 ? 337 PHE B O   1 
ATOM   4984 C CB  . PHE B 2 348 ? 78.091  63.592  100.124 1.00 149.25 ? 337 PHE B CB  1 
ATOM   4985 C CG  . PHE B 2 348 ? 78.462  63.706  98.673  1.00 149.25 ? 337 PHE B CG  1 
ATOM   4986 C CD1 . PHE B 2 348 ? 79.681  63.230  98.216  1.00 149.25 ? 337 PHE B CD1 1 
ATOM   4987 C CD2 . PHE B 2 348 ? 77.599  64.298  97.767  1.00 149.25 ? 337 PHE B CD2 1 
ATOM   4988 C CE1 . PHE B 2 348 ? 80.028  63.338  96.884  1.00 149.25 ? 337 PHE B CE1 1 
ATOM   4989 C CE2 . PHE B 2 348 ? 77.941  64.407  96.432  1.00 149.25 ? 337 PHE B CE2 1 
ATOM   4990 C CZ  . PHE B 2 348 ? 79.158  63.926  95.991  1.00 149.25 ? 337 PHE B CZ  1 
ATOM   4991 N N   . TRP B 2 349 ? 78.591  66.613  100.319 1.00 146.19 ? 338 TRP B N   1 
ATOM   4992 C CA  . TRP B 2 349 ? 78.956  67.888  99.719  1.00 146.19 ? 338 TRP B CA  1 
ATOM   4993 C C   . TRP B 2 349 ? 79.935  68.668  100.583 1.00 146.19 ? 338 TRP B C   1 
ATOM   4994 O O   . TRP B 2 349 ? 80.714  69.463  100.047 1.00 146.19 ? 338 TRP B O   1 
ATOM   4995 C CB  . TRP B 2 349 ? 77.705  68.724  99.446  1.00 146.19 ? 338 TRP B CB  1 
ATOM   4996 C CG  . TRP B 2 349 ? 76.791  68.115  98.421  1.00 146.19 ? 338 TRP B CG  1 
ATOM   4997 C CD1 . TRP B 2 349 ? 75.549  67.594  98.637  1.00 146.19 ? 338 TRP B CD1 1 
ATOM   4998 C CD2 . TRP B 2 349 ? 77.057  67.950  97.023  1.00 146.19 ? 338 TRP B CD2 1 
ATOM   4999 N NE1 . TRP B 2 349 ? 75.022  67.122  97.461  1.00 146.19 ? 338 TRP B NE1 1 
ATOM   5000 C CE2 . TRP B 2 349 ? 75.928  67.328  96.455  1.00 146.19 ? 338 TRP B CE2 1 
ATOM   5001 C CE3 . TRP B 2 349 ? 78.137  68.271  96.196  1.00 146.19 ? 338 TRP B CE3 1 
ATOM   5002 C CZ2 . TRP B 2 349 ? 75.848  67.022  95.100  1.00 146.19 ? 338 TRP B CZ2 1 
ATOM   5003 C CZ3 . TRP B 2 349 ? 78.056  67.965  94.852  1.00 146.19 ? 338 TRP B CZ3 1 
ATOM   5004 C CH2 . TRP B 2 349 ? 76.920  67.347  94.317  1.00 146.19 ? 338 TRP B CH2 1 
ATOM   5005 N N   . LEU B 2 350 ? 79.927  68.458  101.901 1.00 141.11 ? 339 LEU B N   1 
ATOM   5006 C CA  . LEU B 2 350 ? 80.903  69.132  102.746 1.00 141.11 ? 339 LEU B CA  1 
ATOM   5007 C C   . LEU B 2 350 ? 82.300  68.564  102.540 1.00 141.11 ? 339 LEU B C   1 
ATOM   5008 O O   . LEU B 2 350 ? 83.279  69.318  102.507 1.00 141.11 ? 339 LEU B O   1 
ATOM   5009 C CB  . LEU B 2 350 ? 80.482  69.031  104.210 1.00 141.11 ? 339 LEU B CB  1 
ATOM   5010 C CG  . LEU B 2 350 ? 79.495  70.123  104.620 1.00 141.11 ? 339 LEU B CG  1 
ATOM   5011 C CD1 . LEU B 2 350 ? 78.773  69.763  105.906 1.00 141.11 ? 339 LEU B CD1 1 
ATOM   5012 C CD2 . LEU B 2 350 ? 80.219  71.445  104.755 1.00 141.11 ? 339 LEU B CD2 1 
ATOM   5013 N N   . GLN B 2 351 ? 82.414  67.240  102.402 1.00 147.14 ? 340 GLN B N   1 
ATOM   5014 C CA  . GLN B 2 351 ? 83.679  66.657  101.968 1.00 147.14 ? 340 GLN B CA  1 
ATOM   5015 C C   . GLN B 2 351 ? 84.056  67.140  100.575 1.00 147.14 ? 340 GLN B C   1 
ATOM   5016 O O   . GLN B 2 351 ? 85.245  67.263  100.261 1.00 147.14 ? 340 GLN B O   1 
ATOM   5017 C CB  . GLN B 2 351 ? 83.602  65.131  101.996 1.00 147.14 ? 340 GLN B CB  1 
ATOM   5018 C CG  . GLN B 2 351 ? 83.343  64.539  103.368 1.00 147.14 ? 340 GLN B CG  1 
ATOM   5019 C CD  . GLN B 2 351 ? 82.579  63.232  103.301 1.00 147.14 ? 340 GLN B CD  1 
ATOM   5020 O OE1 . GLN B 2 351 ? 82.239  62.646  104.328 1.00 147.14 ? 340 GLN B OE1 1 
ATOM   5021 N NE2 . GLN B 2 351 ? 82.304  62.768  102.088 1.00 147.14 ? 340 GLN B NE2 1 
ATOM   5022 N N   . ALA B 2 352 ? 83.060  67.417  99.729  1.00 144.56 ? 341 ALA B N   1 
ATOM   5023 C CA  . ALA B 2 352 ? 83.345  67.938  98.397  1.00 144.56 ? 341 ALA B CA  1 
ATOM   5024 C C   . ALA B 2 352 ? 83.955  69.333  98.467  1.00 144.56 ? 341 ALA B C   1 
ATOM   5025 O O   . ALA B 2 352 ? 84.883  69.650  97.714  1.00 144.56 ? 341 ALA B O   1 
ATOM   5026 C CB  . ALA B 2 352 ? 82.071  67.948  97.552  1.00 144.56 ? 341 ALA B CB  1 
ATOM   5027 N N   . GLY B 2 353 ? 83.450  70.179  99.362  1.00 137.53 ? 342 GLY B N   1 
ATOM   5028 C CA  . GLY B 2 353 ? 84.033  71.493  99.553  1.00 137.53 ? 342 GLY B CA  1 
ATOM   5029 C C   . GLY B 2 353 ? 83.048  72.644  99.583  1.00 137.53 ? 342 GLY B C   1 
ATOM   5030 O O   . GLY B 2 353 ? 83.455  73.809  99.552  1.00 137.53 ? 342 GLY B O   1 
ATOM   5031 N N   . VAL B 2 354 ? 81.748  72.341  99.635  1.00 129.70 ? 343 VAL B N   1 
ATOM   5032 C CA  . VAL B 2 354 ? 80.764  73.402  99.786  1.00 129.70 ? 343 VAL B CA  1 
ATOM   5033 C C   . VAL B 2 354 ? 80.924  74.031  101.165 1.00 129.70 ? 343 VAL B C   1 
ATOM   5034 O O   . VAL B 2 354 ? 81.380  73.388  102.119 1.00 129.70 ? 343 VAL B O   1 
ATOM   5035 C CB  . VAL B 2 354 ? 79.332  72.879  99.580  1.00 129.70 ? 343 VAL B CB  1 
ATOM   5036 C CG1 . VAL B 2 354 ? 79.240  72.086  98.291  1.00 129.70 ? 343 VAL B CG1 1 
ATOM   5037 C CG2 . VAL B 2 354 ? 78.892  72.042  100.762 1.00 129.70 ? 343 VAL B CG2 1 
ATOM   5038 N N   . ASP B 2 355 ? 80.563  75.305  101.272 1.00 114.78 ? 344 ASP B N   1 
ATOM   5039 C CA  . ASP B 2 355 ? 80.712  76.033  102.523 1.00 114.78 ? 344 ASP B CA  1 
ATOM   5040 C C   . ASP B 2 355 ? 79.385  76.360  103.186 1.00 114.78 ? 344 ASP B C   1 
ATOM   5041 O O   . ASP B 2 355 ? 79.305  77.347  103.921 1.00 114.78 ? 344 ASP B O   1 
ATOM   5042 C CB  . ASP B 2 355 ? 81.502  77.319  102.293 1.00 114.78 ? 344 ASP B CB  1 
ATOM   5043 C CG  . ASP B 2 355 ? 82.989  77.077  102.251 1.00 114.78 ? 344 ASP B CG  1 
ATOM   5044 O OD1 . ASP B 2 355 ? 83.572  76.788  103.315 1.00 114.78 ? 344 ASP B OD1 1 
ATOM   5045 O OD2 . ASP B 2 355 ? 83.575  77.165  101.153 1.00 114.78 ? 344 ASP B OD2 1 
ATOM   5046 N N   . GLY B 2 356 ? 78.351  75.565  102.950 1.00 116.80 ? 345 GLY B N   1 
ATOM   5047 C CA  . GLY B 2 356 ? 77.080  75.798  103.608 1.00 116.80 ? 345 GLY B CA  1 
ATOM   5048 C C   . GLY B 2 356 ? 75.981  75.033  102.910 1.00 116.80 ? 345 GLY B C   1 
ATOM   5049 O O   . GLY B 2 356 ? 76.226  74.246  101.991 1.00 116.80 ? 345 GLY B O   1 
ATOM   5050 N N   . PHE B 2 357 ? 74.753  75.291  103.355 1.00 127.82 ? 346 PHE B N   1 
ATOM   5051 C CA  . PHE B 2 357 ? 73.569  74.676  102.775 1.00 127.82 ? 346 PHE B CA  1 
ATOM   5052 C C   . PHE B 2 357 ? 72.361  75.564  103.036 1.00 127.82 ? 346 PHE B C   1 
ATOM   5053 O O   . PHE B 2 357 ? 72.336  76.347  103.987 1.00 127.82 ? 346 PHE B O   1 
ATOM   5054 C CB  . PHE B 2 357 ? 73.315  73.281  103.354 1.00 127.82 ? 346 PHE B CB  1 
ATOM   5055 C CG  . PHE B 2 357 ? 74.327  72.263  102.938 1.00 127.82 ? 346 PHE B CG  1 
ATOM   5056 C CD1 . PHE B 2 357 ? 74.328  71.755  101.653 1.00 127.82 ? 346 PHE B CD1 1 
ATOM   5057 C CD2 . PHE B 2 357 ? 75.286  71.823  103.828 1.00 127.82 ? 346 PHE B CD2 1 
ATOM   5058 C CE1 . PHE B 2 357 ? 75.261  70.818  101.267 1.00 127.82 ? 346 PHE B CE1 1 
ATOM   5059 C CE2 . PHE B 2 357 ? 76.219  70.885  103.450 1.00 127.82 ? 346 PHE B CE2 1 
ATOM   5060 C CZ  . PHE B 2 357 ? 76.207  70.381  102.168 1.00 127.82 ? 346 PHE B CZ  1 
ATOM   5061 N N   . GLN B 2 358 ? 71.346  75.431  102.183 1.00 126.99 ? 347 GLN B N   1 
ATOM   5062 C CA  . GLN B 2 358 ? 70.067  76.068  102.461 1.00 126.99 ? 347 GLN B CA  1 
ATOM   5063 C C   . GLN B 2 358 ? 68.946  75.128  102.052 1.00 126.99 ? 347 GLN B C   1 
ATOM   5064 O O   . GLN B 2 358 ? 69.121  74.290  101.163 1.00 126.99 ? 347 GLN B O   1 
ATOM   5065 C CB  . GLN B 2 358 ? 69.896  77.405  101.728 1.00 126.99 ? 347 GLN B CB  1 
ATOM   5066 C CG  . GLN B 2 358 ? 69.531  77.274  100.261 1.00 126.99 ? 347 GLN B CG  1 
ATOM   5067 C CD  . GLN B 2 358 ? 69.194  78.607  99.623  1.00 126.99 ? 347 GLN B CD  1 
ATOM   5068 O OE1 . GLN B 2 358 ? 69.264  79.653  100.267 1.00 126.99 ? 347 GLN B OE1 1 
ATOM   5069 N NE2 . GLN B 2 358 ? 68.781  78.570  98.361  1.00 126.99 ? 347 GLN B NE2 1 
ATOM   5070 N N   . VAL B 2 359 ? 67.808  75.264  102.719 1.00 134.58 ? 348 VAL B N   1 
ATOM   5071 C CA  . VAL B 2 359 ? 66.576  74.596  102.333 1.00 134.58 ? 348 VAL B CA  1 
ATOM   5072 C C   . VAL B 2 359 ? 65.476  75.646  102.285 1.00 134.58 ? 348 VAL B C   1 
ATOM   5073 O O   . VAL B 2 359 ? 65.588  76.721  102.876 1.00 134.58 ? 348 VAL B O   1 
ATOM   5074 C CB  . VAL B 2 359 ? 66.203  73.448  103.290 1.00 134.58 ? 348 VAL B CB  1 
ATOM   5075 C CG1 . VAL B 2 359 ? 67.365  72.479  103.436 1.00 134.58 ? 348 VAL B CG1 1 
ATOM   5076 C CG2 . VAL B 2 359 ? 65.800  74.003  104.642 1.00 134.58 ? 348 VAL B CG2 1 
ATOM   5077 N N   . ARG B 2 360 ? 64.402  75.327  101.569 1.00 139.97 ? 349 ARG B N   1 
ATOM   5078 C CA  . ARG B 2 360 ? 63.314  76.271  101.368 1.00 139.97 ? 349 ARG B CA  1 
ATOM   5079 C C   . ARG B 2 360 ? 61.986  75.625  101.736 1.00 139.97 ? 349 ARG B C   1 
ATOM   5080 O O   . ARG B 2 360 ? 61.827  74.402  101.692 1.00 139.97 ? 349 ARG B O   1 
ATOM   5081 C CB  . ARG B 2 360 ? 63.278  76.780  99.920  1.00 139.97 ? 349 ARG B CB  1 
ATOM   5082 C CG  . ARG B 2 360 ? 64.313  77.850  99.621  1.00 139.97 ? 349 ARG B CG  1 
ATOM   5083 C CD  . ARG B 2 360 ? 64.152  78.404  98.217  1.00 139.97 ? 349 ARG B CD  1 
ATOM   5084 N NE  . ARG B 2 360 ? 64.995  77.705  97.254  1.00 139.97 ? 349 ARG B NE  1 
ATOM   5085 C CZ  . ARG B 2 360 ? 64.561  76.755  96.432  1.00 139.97 ? 349 ARG B CZ  1 
ATOM   5086 N NH1 . ARG B 2 360 ? 63.288  76.386  96.455  1.00 139.97 ? 349 ARG B NH1 1 
ATOM   5087 N NH2 . ARG B 2 360 ? 65.400  76.176  95.588  1.00 139.97 ? 349 ARG B NH2 1 
ATOM   5088 N N   . ASP B 2 361 ? 61.031  76.479  102.108 1.00 145.15 ? 350 ASP B N   1 
ATOM   5089 C CA  . ASP B 2 361 ? 59.668  76.059  102.433 1.00 145.15 ? 350 ASP B CA  1 
ATOM   5090 C C   . ASP B 2 361 ? 59.654  75.051  103.579 1.00 145.15 ? 350 ASP B C   1 
ATOM   5091 O O   . ASP B 2 361 ? 59.072  73.971  103.476 1.00 145.15 ? 350 ASP B O   1 
ATOM   5092 C CB  . ASP B 2 361 ? 58.960  75.492  101.202 1.00 145.15 ? 350 ASP B CB  1 
ATOM   5093 C CG  . ASP B 2 361 ? 59.159  76.351  99.971  1.00 145.15 ? 350 ASP B CG  1 
ATOM   5094 O OD1 . ASP B 2 361 ? 58.563  77.447  99.904  1.00 145.15 ? 350 ASP B OD1 1 
ATOM   5095 O OD2 . ASP B 2 361 ? 59.911  75.929  99.068  1.00 145.15 ? 350 ASP B OD2 1 
ATOM   5096 N N   . ILE B 2 362 ? 60.300  75.411  104.691 1.00 146.76 ? 351 ILE B N   1 
ATOM   5097 C CA  . ILE B 2 362 ? 60.373  74.498  105.830 1.00 146.76 ? 351 ILE B CA  1 
ATOM   5098 C C   . ILE B 2 362 ? 58.996  74.291  106.445 1.00 146.76 ? 351 ILE B C   1 
ATOM   5099 O O   . ILE B 2 362 ? 58.751  73.294  107.137 1.00 146.76 ? 351 ILE B O   1 
ATOM   5100 C CB  . ILE B 2 362 ? 61.386  75.015  106.869 1.00 146.76 ? 351 ILE B CB  1 
ATOM   5101 C CG1 . ILE B 2 362 ? 61.181  76.507  107.123 1.00 146.76 ? 351 ILE B CG1 1 
ATOM   5102 C CG2 . ILE B 2 362 ? 62.801  74.735  106.413 1.00 146.76 ? 351 ILE B CG2 1 
ATOM   5103 C CD1 . ILE B 2 362 ? 61.670  76.961  108.476 1.00 146.76 ? 351 ILE B CD1 1 
ATOM   5104 N N   . GLU B 2 363 ? 58.077  75.225  106.208 1.00 146.82 ? 352 GLU B N   1 
ATOM   5105 C CA  . GLU B 2 363 ? 56.707  75.078  106.685 1.00 146.82 ? 352 GLU B CA  1 
ATOM   5106 C C   . GLU B 2 363 ? 55.990  73.969  105.925 1.00 146.82 ? 352 GLU B C   1 
ATOM   5107 O O   . GLU B 2 363 ? 54.955  73.467  106.375 1.00 146.82 ? 352 GLU B O   1 
ATOM   5108 C CB  . GLU B 2 363 ? 55.945  76.398  106.549 1.00 146.82 ? 352 GLU B CB  1 
ATOM   5109 C CG  . GLU B 2 363 ? 55.464  76.699  105.139 1.00 146.82 ? 352 GLU B CG  1 
ATOM   5110 C CD  . GLU B 2 363 ? 56.602  76.993  104.182 1.00 146.82 ? 352 GLU B CD  1 
ATOM   5111 O OE1 . GLU B 2 363 ? 57.709  77.321  104.656 1.00 146.82 ? 352 GLU B OE1 1 
ATOM   5112 O OE2 . GLU B 2 363 ? 56.388  76.896  102.956 1.00 146.82 ? 352 GLU B OE2 1 
ATOM   5113 N N   . ASN B 2 364 ? 56.531  73.585  104.770 1.00 155.18 ? 353 ASN B N   1 
ATOM   5114 C CA  . ASN B 2 364 ? 56.002  72.464  104.008 1.00 155.18 ? 353 ASN B CA  1 
ATOM   5115 C C   . ASN B 2 364 ? 56.491  71.121  104.531 1.00 155.18 ? 353 ASN B C   1 
ATOM   5116 O O   . ASN B 2 364 ? 55.833  70.101  104.299 1.00 155.18 ? 353 ASN B O   1 
ATOM   5117 C CB  . ASN B 2 364 ? 56.379  72.614  102.529 1.00 155.18 ? 353 ASN B CB  1 
ATOM   5118 C CG  . ASN B 2 364 ? 55.889  71.461  101.678 1.00 155.18 ? 353 ASN B CG  1 
ATOM   5119 O OD1 . ASN B 2 364 ? 54.756  71.003  101.823 1.00 155.18 ? 353 ASN B OD1 1 
ATOM   5120 N ND2 . ASN B 2 364 ? 56.745  70.984  100.782 1.00 155.18 ? 353 ASN B ND2 1 
ATOM   5121 N N   . LEU B 2 365 ? 57.614  71.104  105.243 1.00 157.50 ? 354 LEU B N   1 
ATOM   5122 C CA  . LEU B 2 365 ? 58.172  69.889  105.823 1.00 157.50 ? 354 LEU B CA  1 
ATOM   5123 C C   . LEU B 2 365 ? 57.630  69.711  107.235 1.00 157.50 ? 354 LEU B C   1 
ATOM   5124 O O   . LEU B 2 365 ? 57.915  70.525  108.120 1.00 157.50 ? 354 LEU B O   1 
ATOM   5125 C CB  . LEU B 2 365 ? 59.701  69.953  105.830 1.00 157.50 ? 354 LEU B CB  1 
ATOM   5126 C CG  . LEU B 2 365 ? 60.514  68.770  106.359 1.00 157.50 ? 354 LEU B CG  1 
ATOM   5127 C CD1 . LEU B 2 365 ? 61.803  68.633  105.587 1.00 157.50 ? 354 LEU B CD1 1 
ATOM   5128 C CD2 . LEU B 2 365 ? 60.844  68.978  107.822 1.00 157.50 ? 354 LEU B CD2 1 
ATOM   5129 N N   . LYS B 2 366 ? 56.852  68.651  107.443 1.00 160.85 ? 355 LYS B N   1 
ATOM   5130 C CA  . LYS B 2 366 ? 56.415  68.319  108.789 1.00 160.85 ? 355 LYS B CA  1 
ATOM   5131 C C   . LYS B 2 366 ? 57.598  67.812  109.607 1.00 160.85 ? 355 LYS B C   1 
ATOM   5132 O O   . LYS B 2 366 ? 58.574  67.280  109.071 1.00 160.85 ? 355 LYS B O   1 
ATOM   5133 C CB  . LYS B 2 366 ? 55.298  67.276  108.758 1.00 160.85 ? 355 LYS B CB  1 
ATOM   5134 C CG  . LYS B 2 366 ? 55.697  65.934  108.166 1.00 160.85 ? 355 LYS B CG  1 
ATOM   5135 C CD  . LYS B 2 366 ? 54.585  65.385  107.287 1.00 160.85 ? 355 LYS B CD  1 
ATOM   5136 C CE  . LYS B 2 366 ? 55.031  64.152  106.521 1.00 160.85 ? 355 LYS B CE  1 
ATOM   5137 N NZ  . LYS B 2 366 ? 54.200  63.917  105.307 1.00 160.85 ? 355 LYS B NZ  1 
ATOM   5138 N N   . ASP B 2 367 ? 57.491  67.969  110.928 1.00 157.59 ? 356 ASP B N   1 
ATOM   5139 C CA  . ASP B 2 367 ? 58.632  67.821  111.832 1.00 157.59 ? 356 ASP B CA  1 
ATOM   5140 C C   . ASP B 2 367 ? 59.744  68.776  111.398 1.00 157.59 ? 356 ASP B C   1 
ATOM   5141 O O   . ASP B 2 367 ? 60.879  68.382  111.127 1.00 157.59 ? 356 ASP B O   1 
ATOM   5142 C CB  . ASP B 2 367 ? 59.113  66.365  111.894 1.00 157.59 ? 356 ASP B CB  1 
ATOM   5143 C CG  . ASP B 2 367 ? 60.133  66.120  112.997 1.00 157.59 ? 356 ASP B CG  1 
ATOM   5144 O OD1 . ASP B 2 367 ? 61.313  66.490  112.833 1.00 157.59 ? 356 ASP B OD1 1 
ATOM   5145 O OD2 . ASP B 2 367 ? 59.745  65.555  114.041 1.00 157.59 ? 356 ASP B OD2 1 
ATOM   5146 N N   . ALA B 2 368 ? 59.382  70.056  111.293 1.00 156.04 ? 357 ALA B N   1 
ATOM   5147 C CA  . ALA B 2 368 ? 60.311  71.057  110.780 1.00 156.04 ? 357 ALA B CA  1 
ATOM   5148 C C   . ALA B 2 368 ? 61.406  71.362  111.792 1.00 156.04 ? 357 ALA B C   1 
ATOM   5149 O O   . ALA B 2 368 ? 62.598  71.255  111.483 1.00 156.04 ? 357 ALA B O   1 
ATOM   5150 C CB  . ALA B 2 368 ? 59.552  72.330  110.403 1.00 156.04 ? 357 ALA B CB  1 
ATOM   5151 N N   . SER B 2 369 ? 61.014  71.746  113.009 1.00 152.93 ? 358 SER B N   1 
ATOM   5152 C CA  . SER B 2 369 ? 61.987  72.180  114.006 1.00 152.93 ? 358 SER B CA  1 
ATOM   5153 C C   . SER B 2 369 ? 63.007  71.090  114.306 1.00 152.93 ? 358 SER B C   1 
ATOM   5154 O O   . SER B 2 369 ? 64.213  71.351  114.324 1.00 152.93 ? 358 SER B O   1 
ATOM   5155 C CB  . SER B 2 369 ? 61.268  72.608  115.284 1.00 152.93 ? 358 SER B CB  1 
ATOM   5156 O OG  . SER B 2 369 ? 60.139  73.411  114.986 1.00 152.93 ? 358 SER B OG  1 
ATOM   5157 N N   . SER B 2 370 ? 62.548  69.854  114.512 1.00 153.59 ? 359 SER B N   1 
ATOM   5158 C CA  . SER B 2 370 ? 63.453  68.792  114.943 1.00 153.59 ? 359 SER B CA  1 
ATOM   5159 C C   . SER B 2 370 ? 64.384  68.343  113.821 1.00 153.59 ? 359 SER B C   1 
ATOM   5160 O O   . SER B 2 370 ? 65.595  68.216  114.034 1.00 153.59 ? 359 SER B O   1 
ATOM   5161 C CB  . SER B 2 370 ? 62.649  67.608  115.479 1.00 153.59 ? 359 SER B CB  1 
ATOM   5162 O OG  . SER B 2 370 ? 61.615  68.045  116.345 1.00 153.59 ? 359 SER B OG  1 
ATOM   5163 N N   . PHE B 2 371 ? 63.842  68.088  112.628 1.00 154.82 ? 360 PHE B N   1 
ATOM   5164 C CA  . PHE B 2 371 ? 64.690  67.711  111.501 1.00 154.82 ? 360 PHE B CA  1 
ATOM   5165 C C   . PHE B 2 371 ? 65.681  68.817  111.168 1.00 154.82 ? 360 PHE B C   1 
ATOM   5166 O O   . PHE B 2 371 ? 66.848  68.550  110.849 1.00 154.82 ? 360 PHE B O   1 
ATOM   5167 C CB  . PHE B 2 371 ? 63.829  67.385  110.282 1.00 154.82 ? 360 PHE B CB  1 
ATOM   5168 C CG  . PHE B 2 371 ? 63.382  65.954  110.218 1.00 154.82 ? 360 PHE B CG  1 
ATOM   5169 C CD1 . PHE B 2 371 ? 64.260  64.926  110.516 1.00 154.82 ? 360 PHE B CD1 1 
ATOM   5170 C CD2 . PHE B 2 371 ? 62.084  65.637  109.855 1.00 154.82 ? 360 PHE B CD2 1 
ATOM   5171 C CE1 . PHE B 2 371 ? 63.850  63.609  110.457 1.00 154.82 ? 360 PHE B CE1 1 
ATOM   5172 C CE2 . PHE B 2 371 ? 61.668  64.322  109.793 1.00 154.82 ? 360 PHE B CE2 1 
ATOM   5173 C CZ  . PHE B 2 371 ? 62.552  63.307  110.094 1.00 154.82 ? 360 PHE B CZ  1 
ATOM   5174 N N   . LEU B 2 372 ? 65.233  70.071  111.243 1.00 147.68 ? 361 LEU B N   1 
ATOM   5175 C CA  . LEU B 2 372 ? 66.110  71.187  110.923 1.00 147.68 ? 361 LEU B CA  1 
ATOM   5176 C C   . LEU B 2 372 ? 67.196  71.347  111.979 1.00 147.68 ? 361 LEU B C   1 
ATOM   5177 O O   . LEU B 2 372 ? 68.346  71.651  111.650 1.00 147.68 ? 361 LEU B O   1 
ATOM   5178 C CB  . LEU B 2 372 ? 65.279  72.459  110.781 1.00 147.68 ? 361 LEU B CB  1 
ATOM   5179 C CG  . LEU B 2 372 ? 65.961  73.736  110.311 1.00 147.68 ? 361 LEU B CG  1 
ATOM   5180 C CD1 . LEU B 2 372 ? 66.555  73.530  108.935 1.00 147.68 ? 361 LEU B CD1 1 
ATOM   5181 C CD2 . LEU B 2 372 ? 64.925  74.836  110.273 1.00 147.68 ? 361 LEU B CD2 1 
ATOM   5182 N N   . ALA B 2 373 ? 66.855  71.121  113.250 1.00 148.92 ? 362 ALA B N   1 
ATOM   5183 C CA  . ALA B 2 373 ? 67.866  71.122  114.300 1.00 148.92 ? 362 ALA B CA  1 
ATOM   5184 C C   . ALA B 2 373 ? 68.871  70.000  114.094 1.00 148.92 ? 362 ALA B C   1 
ATOM   5185 O O   . ALA B 2 373 ? 70.067  70.174  114.348 1.00 148.92 ? 362 ALA B O   1 
ATOM   5186 C CB  . ALA B 2 373 ? 67.199  71.002  115.670 1.00 148.92 ? 362 ALA B CB  1 
ATOM   5187 N N   . GLU B 2 374 ? 68.406  68.838  113.634 1.00 152.85 ? 363 GLU B N   1 
ATOM   5188 C CA  . GLU B 2 374 ? 69.323  67.728  113.396 1.00 152.85 ? 363 GLU B CA  1 
ATOM   5189 C C   . GLU B 2 374 ? 70.282  68.046  112.254 1.00 152.85 ? 363 GLU B C   1 
ATOM   5190 O O   . GLU B 2 374 ? 71.485  67.772  112.349 1.00 152.85 ? 363 GLU B O   1 
ATOM   5191 C CB  . GLU B 2 374 ? 68.532  66.449  113.114 1.00 152.85 ? 363 GLU B CB  1 
ATOM   5192 C CG  . GLU B 2 374 ? 69.380  65.192  112.979 1.00 152.85 ? 363 GLU B CG  1 
ATOM   5193 C CD  . GLU B 2 374 ? 69.831  64.925  111.558 1.00 152.85 ? 363 GLU B CD  1 
ATOM   5194 O OE1 . GLU B 2 374 ? 70.565  63.937  111.350 1.00 152.85 ? 363 GLU B OE1 1 
ATOM   5195 O OE2 . GLU B 2 374 ? 69.442  65.686  110.649 1.00 152.85 ? 363 GLU B OE2 1 
ATOM   5196 N N   . TRP B 2 375 ? 69.769  68.629  111.169 1.00 150.01 ? 364 TRP B N   1 
ATOM   5197 C CA  . TRP B 2 375 ? 70.647  69.051  110.080 1.00 150.01 ? 364 TRP B CA  1 
ATOM   5198 C C   . TRP B 2 375 ? 71.616  70.133  110.545 1.00 150.01 ? 364 TRP B C   1 
ATOM   5199 O O   . TRP B 2 375 ? 72.779  70.162  110.120 1.00 150.01 ? 364 TRP B O   1 
ATOM   5200 C CB  . TRP B 2 375 ? 69.817  69.540  108.893 1.00 150.01 ? 364 TRP B CB  1 
ATOM   5201 C CG  . TRP B 2 375 ? 68.983  68.471  108.259 1.00 150.01 ? 364 TRP B CG  1 
ATOM   5202 C CD1 . TRP B 2 375 ? 69.355  67.185  108.006 1.00 150.01 ? 364 TRP B CD1 1 
ATOM   5203 C CD2 . TRP B 2 375 ? 67.634  68.597  107.793 1.00 150.01 ? 364 TRP B CD2 1 
ATOM   5204 N NE1 . TRP B 2 375 ? 68.322  66.499  107.416 1.00 150.01 ? 364 TRP B NE1 1 
ATOM   5205 C CE2 . TRP B 2 375 ? 67.254  67.345  107.274 1.00 150.01 ? 364 TRP B CE2 1 
ATOM   5206 C CE3 . TRP B 2 375 ? 66.712  69.646  107.768 1.00 150.01 ? 364 TRP B CE3 1 
ATOM   5207 C CZ2 . TRP B 2 375 ? 65.992  67.115  106.733 1.00 150.01 ? 364 TRP B CZ2 1 
ATOM   5208 C CZ3 . TRP B 2 375 ? 65.459  69.414  107.232 1.00 150.01 ? 364 TRP B CZ3 1 
ATOM   5209 C CH2 . TRP B 2 375 ? 65.111  68.159  106.722 1.00 150.01 ? 364 TRP B CH2 1 
ATOM   5210 N N   . GLN B 2 376 ? 71.144  71.042  111.403 1.00 143.19 ? 365 GLN B N   1 
ATOM   5211 C CA  . GLN B 2 376 ? 72.022  72.026  112.025 1.00 143.19 ? 365 GLN B CA  1 
ATOM   5212 C C   . GLN B 2 376 ? 73.156  71.349  112.783 1.00 143.19 ? 365 GLN B C   1 
ATOM   5213 O O   . GLN B 2 376 ? 74.320  71.750  112.668 1.00 143.19 ? 365 GLN B O   1 
ATOM   5214 C CB  . GLN B 2 376 ? 71.208  72.920  112.961 1.00 143.19 ? 365 GLN B CB  1 
ATOM   5215 C CG  . GLN B 2 376 ? 72.040  73.803  113.868 1.00 143.19 ? 365 GLN B CG  1 
ATOM   5216 C CD  . GLN B 2 376 ? 72.579  75.019  113.155 1.00 143.19 ? 365 GLN B CD  1 
ATOM   5217 O OE1 . GLN B 2 376 ? 73.651  74.976  112.555 1.00 143.19 ? 365 GLN B OE1 1 
ATOM   5218 N NE2 . GLN B 2 376 ? 71.842  76.120  113.226 1.00 143.19 ? 365 GLN B NE2 1 
ATOM   5219 N N   . ASN B 2 377 ? 72.829  70.327  113.576 1.00 144.97 ? 366 ASN B N   1 
ATOM   5220 C CA  . ASN B 2 377 ? 73.855  69.604  114.319 1.00 144.97 ? 366 ASN B CA  1 
ATOM   5221 C C   . ASN B 2 377 ? 74.842  68.931  113.377 1.00 144.97 ? 366 ASN B C   1 
ATOM   5222 O O   . ASN B 2 377 ? 76.045  68.904  113.643 1.00 144.97 ? 366 ASN B O   1 
ATOM   5223 C CB  . ASN B 2 377 ? 73.213  68.576  115.252 1.00 144.97 ? 366 ASN B CB  1 
ATOM   5224 C CG  . ASN B 2 377 ? 72.127  69.175  116.119 1.00 144.97 ? 366 ASN B CG  1 
ATOM   5225 O OD1 . ASN B 2 377 ? 72.287  70.265  116.668 1.00 144.97 ? 366 ASN B OD1 1 
ATOM   5226 N ND2 . ASN B 2 377 ? 71.011  68.467  116.244 1.00 144.97 ? 366 ASN B ND2 1 
ATOM   5227 N N   . ILE B 2 378 ? 74.351  68.385  112.263 1.00 142.87 ? 367 ILE B N   1 
ATOM   5228 C CA  . ILE B 2 378 ? 75.252  67.770  111.288 1.00 142.87 ? 367 ILE B CA  1 
ATOM   5229 C C   . ILE B 2 378 ? 76.233  68.801  110.743 1.00 142.87 ? 367 ILE B C   1 
ATOM   5230 O O   . ILE B 2 378 ? 77.456  68.601  110.768 1.00 142.87 ? 367 ILE B O   1 
ATOM   5231 C CB  . ILE B 2 378 ? 74.457  67.105  110.150 1.00 142.87 ? 367 ILE B CB  1 
ATOM   5232 C CG1 . ILE B 2 378 ? 73.494  66.053  110.697 1.00 142.87 ? 367 ILE B CG1 1 
ATOM   5233 C CG2 . ILE B 2 378 ? 75.407  66.492  109.133 1.00 142.87 ? 367 ILE B CG2 1 
ATOM   5234 C CD1 . ILE B 2 378 ? 72.944  65.131  109.632 1.00 142.87 ? 367 ILE B CD1 1 
ATOM   5235 N N   . THR B 2 379 ? 75.710  69.922  110.239 1.00 138.76 ? 368 THR B N   1 
ATOM   5236 C CA  . THR B 2 379 ? 76.580  70.891  109.579 1.00 138.76 ? 368 THR B CA  1 
ATOM   5237 C C   . THR B 2 379 ? 77.495  71.587  110.579 1.00 138.76 ? 368 THR B C   1 
ATOM   5238 O O   . THR B 2 379 ? 78.560  72.090  110.204 1.00 138.76 ? 368 THR B O   1 
ATOM   5239 C CB  . THR B 2 379 ? 75.757  71.915  108.798 1.00 138.76 ? 368 THR B CB  1 
ATOM   5240 O OG1 . THR B 2 379 ? 76.637  72.883  108.214 1.00 138.76 ? 368 THR B OG1 1 
ATOM   5241 C CG2 . THR B 2 379 ? 74.781  72.629  109.707 1.00 138.76 ? 368 THR B CG2 1 
ATOM   5242 N N   . LYS B 2 380 ? 77.105  71.627  111.855 1.00 138.51 ? 369 LYS B N   1 
ATOM   5243 C CA  . LYS B 2 380 ? 78.001  72.174  112.868 1.00 138.51 ? 369 LYS B CA  1 
ATOM   5244 C C   . LYS B 2 380 ? 79.045  71.155  113.304 1.00 138.51 ? 369 LYS B C   1 
ATOM   5245 O O   . LYS B 2 380 ? 80.168  71.532  113.655 1.00 138.51 ? 369 LYS B O   1 
ATOM   5246 C CB  . LYS B 2 380 ? 77.199  72.671  114.070 1.00 138.51 ? 369 LYS B CB  1 
ATOM   5247 C CG  . LYS B 2 380 ? 76.459  73.970  113.811 1.00 138.51 ? 369 LYS B CG  1 
ATOM   5248 C CD  . LYS B 2 380 ? 77.354  74.972  113.099 1.00 138.51 ? 369 LYS B CD  1 
ATOM   5249 C CE  . LYS B 2 380 ? 76.576  76.200  112.658 1.00 138.51 ? 369 LYS B CE  1 
ATOM   5250 N NZ  . LYS B 2 380 ? 77.392  77.093  111.792 1.00 138.51 ? 369 LYS B NZ  1 
ATOM   5251 N N   . GLY B 2 381 ? 78.697  69.866  113.293 1.00 139.62 ? 370 GLY B N   1 
ATOM   5252 C CA  . GLY B 2 381 ? 79.665  68.843  113.630 1.00 139.62 ? 370 GLY B CA  1 
ATOM   5253 C C   . GLY B 2 381 ? 80.710  68.638  112.561 1.00 139.62 ? 370 GLY B C   1 
ATOM   5254 O O   . GLY B 2 381 ? 81.838  68.240  112.867 1.00 139.62 ? 370 GLY B O   1 
ATOM   5255 N N   . PHE B 2 382 ? 80.363  68.899  111.298 1.00 137.98 ? 371 PHE B N   1 
ATOM   5256 C CA  . PHE B 2 382 ? 81.381  68.823  110.255 1.00 137.98 ? 371 PHE B CA  1 
ATOM   5257 C C   . PHE B 2 382 ? 82.391  69.955  110.391 1.00 137.98 ? 371 PHE B C   1 
ATOM   5258 O O   . PHE B 2 382 ? 83.599  69.734  110.248 1.00 137.98 ? 371 PHE B O   1 
ATOM   5259 C CB  . PHE B 2 382 ? 80.736  68.839  108.871 1.00 137.98 ? 371 PHE B CB  1 
ATOM   5260 C CG  . PHE B 2 382 ? 81.607  68.252  107.795 1.00 137.98 ? 371 PHE B CG  1 
ATOM   5261 C CD1 . PHE B 2 382 ? 82.715  68.939  107.328 1.00 137.98 ? 371 PHE B CD1 1 
ATOM   5262 C CD2 . PHE B 2 382 ? 81.323  67.009  107.257 1.00 137.98 ? 371 PHE B CD2 1 
ATOM   5263 C CE1 . PHE B 2 382 ? 83.520  68.401  106.344 1.00 137.98 ? 371 PHE B CE1 1 
ATOM   5264 C CE2 . PHE B 2 382 ? 82.124  66.465  106.271 1.00 137.98 ? 371 PHE B CE2 1 
ATOM   5265 C CZ  . PHE B 2 382 ? 83.223  67.162  105.814 1.00 137.98 ? 371 PHE B CZ  1 
ATOM   5266 N N   . SER B 2 383 ? 81.921  71.169  110.665 1.00 128.69 ? 372 SER B N   1 
ATOM   5267 C CA  . SER B 2 383 ? 82.793  72.316  110.897 1.00 128.69 ? 372 SER B CA  1 
ATOM   5268 C C   . SER B 2 383 ? 81.967  73.413  111.555 1.00 128.69 ? 372 SER B C   1 
ATOM   5269 O O   . SER B 2 383 ? 80.739  73.327  111.637 1.00 128.69 ? 372 SER B O   1 
ATOM   5270 C CB  . SER B 2 383 ? 83.436  72.817  109.598 1.00 128.69 ? 372 SER B CB  1 
ATOM   5271 O OG  . SER B 2 383 ? 83.957  71.756  108.816 1.00 128.69 ? 372 SER B OG  1 
ATOM   5272 N N   . GLU B 2 384 ? 82.651  74.458  112.020 1.00 121.23 ? 373 GLU B N   1 
ATOM   5273 C CA  . GLU B 2 384 ? 81.969  75.585  112.641 1.00 121.23 ? 373 GLU B CA  1 
ATOM   5274 C C   . GLU B 2 384 ? 81.869  76.799  111.730 1.00 121.23 ? 373 GLU B C   1 
ATOM   5275 O O   . GLU B 2 384 ? 81.178  77.760  112.083 1.00 121.23 ? 373 GLU B O   1 
ATOM   5276 C CB  . GLU B 2 384 ? 82.665  75.981  113.950 1.00 121.23 ? 373 GLU B CB  1 
ATOM   5277 C CG  . GLU B 2 384 ? 84.087  76.501  113.807 1.00 121.23 ? 373 GLU B CG  1 
ATOM   5278 C CD  . GLU B 2 384 ? 84.147  78.007  113.633 1.00 121.23 ? 373 GLU B CD  1 
ATOM   5279 O OE1 . GLU B 2 384 ? 83.149  78.685  113.954 1.00 121.23 ? 373 GLU B OE1 1 
ATOM   5280 O OE2 . GLU B 2 384 ? 85.197  78.514  113.188 1.00 121.23 ? 373 GLU B OE2 1 
ATOM   5281 N N   . ASP B 2 385 ? 82.538  76.784  110.577 1.00 114.87 ? 374 ASP B N   1 
ATOM   5282 C CA  . ASP B 2 385 ? 82.399  77.832  109.575 1.00 114.87 ? 374 ASP B CA  1 
ATOM   5283 C C   . ASP B 2 385 ? 81.508  77.402  108.415 1.00 114.87 ? 374 ASP B C   1 
ATOM   5284 O O   . ASP B 2 385 ? 81.694  77.859  107.284 1.00 114.87 ? 374 ASP B O   1 
ATOM   5285 C CB  . ASP B 2 385 ? 83.770  78.269  109.062 1.00 114.87 ? 374 ASP B CB  1 
ATOM   5286 C CG  . ASP B 2 385 ? 84.351  79.417  109.863 1.00 114.87 ? 374 ASP B CG  1 
ATOM   5287 O OD1 . ASP B 2 385 ? 83.863  79.664  110.985 1.00 114.87 ? 374 ASP B OD1 1 
ATOM   5288 O OD2 . ASP B 2 385 ? 85.293  80.074  109.371 1.00 114.87 ? 374 ASP B OD2 1 
ATOM   5289 N N   . ARG B 2 386 ? 80.546  76.526  108.679 1.00 118.59 ? 375 ARG B N   1 
ATOM   5290 C CA  . ARG B 2 386 ? 79.547  76.120  107.706 1.00 118.59 ? 375 ARG B CA  1 
ATOM   5291 C C   . ARG B 2 386 ? 78.219  76.785  108.040 1.00 118.59 ? 375 ARG B C   1 
ATOM   5292 O O   . ARG B 2 386 ? 78.048  77.369  109.113 1.00 118.59 ? 375 ARG B O   1 
ATOM   5293 C CB  . ARG B 2 386 ? 79.393  74.597  107.678 1.00 118.59 ? 375 ARG B CB  1 
ATOM   5294 C CG  . ARG B 2 386 ? 80.685  73.863  107.365 1.00 118.59 ? 375 ARG B CG  1 
ATOM   5295 C CD  . ARG B 2 386 ? 81.400  74.495  106.184 1.00 118.59 ? 375 ARG B CD  1 
ATOM   5296 N NE  . ARG B 2 386 ? 82.703  73.887  105.937 1.00 118.59 ? 375 ARG B NE  1 
ATOM   5297 C CZ  . ARG B 2 386 ? 83.863  74.466  106.227 1.00 118.59 ? 375 ARG B CZ  1 
ATOM   5298 N NH1 . ARG B 2 386 ? 83.883  75.672  106.777 1.00 118.59 ? 375 ARG B NH1 1 
ATOM   5299 N NH2 . ARG B 2 386 ? 85.002  73.842  105.967 1.00 118.59 ? 375 ARG B NH2 1 
ATOM   5300 N N   . LEU B 2 387 ? 77.272  76.691  107.111 1.00 113.50 ? 376 LEU B N   1 
ATOM   5301 C CA  . LEU B 2 387 ? 76.037  77.452  107.207 1.00 113.50 ? 376 LEU B CA  1 
ATOM   5302 C C   . LEU B 2 387 ? 74.835  76.615  106.802 1.00 113.50 ? 376 LEU B C   1 
ATOM   5303 O O   . LEU B 2 387 ? 74.905  75.790  105.888 1.00 113.50 ? 376 LEU B O   1 
ATOM   5304 C CB  . LEU B 2 387 ? 76.095  78.703  106.335 1.00 113.50 ? 376 LEU B CB  1 
ATOM   5305 C CG  . LEU B 2 387 ? 75.058  79.765  106.677 1.00 113.50 ? 376 LEU B CG  1 
ATOM   5306 C CD1 . LEU B 2 387 ? 75.088  80.059  108.160 1.00 113.50 ? 376 LEU B CD1 1 
ATOM   5307 C CD2 . LEU B 2 387 ? 75.323  81.017  105.874 1.00 113.50 ? 376 LEU B CD2 1 
ATOM   5308 N N   . LEU B 2 388 ? 73.724  76.847  107.497 1.00 118.34 ? 377 LEU B N   1 
ATOM   5309 C CA  . LEU B 2 388 ? 72.442  76.250  107.147 1.00 118.34 ? 377 LEU B CA  1 
ATOM   5310 C C   . LEU B 2 388 ? 71.393  77.346  107.213 1.00 118.34 ? 377 LEU B C   1 
ATOM   5311 O O   . LEU B 2 388 ? 71.158  77.917  108.281 1.00 118.34 ? 377 LEU B O   1 
ATOM   5312 C CB  . LEU B 2 388 ? 72.089  75.097  108.088 1.00 118.34 ? 377 LEU B CB  1 
ATOM   5313 C CG  . LEU B 2 388 ? 71.096  74.046  107.587 1.00 118.34 ? 377 LEU B CG  1 
ATOM   5314 C CD1 . LEU B 2 388 ? 71.139  72.847  108.504 1.00 118.34 ? 377 LEU B CD1 1 
ATOM   5315 C CD2 . LEU B 2 388 ? 69.679  74.580  107.497 1.00 118.34 ? 377 LEU B CD2 1 
ATOM   5316 N N   . ILE B 2 389 ? 70.769  77.637  106.076 1.00 118.43 ? 378 ILE B N   1 
ATOM   5317 C CA  . ILE B 2 389 ? 69.784  78.706  105.963 1.00 118.43 ? 378 ILE B CA  1 
ATOM   5318 C C   . ILE B 2 389 ? 68.450  78.094  105.570 1.00 118.43 ? 378 ILE B C   1 
ATOM   5319 O O   . ILE B 2 389 ? 68.330  77.484  104.500 1.00 118.43 ? 378 ILE B O   1 
ATOM   5320 C CB  . ILE B 2 389 ? 70.212  79.770  104.945 1.00 118.43 ? 378 ILE B CB  1 
ATOM   5321 C CG1 . ILE B 2 389 ? 71.422  80.540  105.463 1.00 118.43 ? 378 ILE B CG1 1 
ATOM   5322 C CG2 . ILE B 2 389 ? 69.068  80.718  104.664 1.00 118.43 ? 378 ILE B CG2 1 
ATOM   5323 C CD1 . ILE B 2 389 ? 71.977  81.512  104.464 1.00 118.43 ? 378 ILE B CD1 1 
ATOM   5324 N N   . ALA B 2 390 ? 67.446  78.269  106.418 1.00 123.43 ? 379 ALA B N   1 
ATOM   5325 C CA  . ALA B 2 390 ? 66.109  77.759  106.156 1.00 123.43 ? 379 ALA B CA  1 
ATOM   5326 C C   . ALA B 2 390 ? 65.211  78.907  105.724 1.00 123.43 ? 379 ALA B C   1 
ATOM   5327 O O   . ALA B 2 390 ? 65.209  79.970  106.353 1.00 123.43 ? 379 ALA B O   1 
ATOM   5328 C CB  . ALA B 2 390 ? 65.532  77.072  107.392 1.00 123.43 ? 379 ALA B CB  1 
ATOM   5329 N N   . GLY B 2 391 ? 64.456  78.691  104.652 1.00 133.94 ? 380 GLY B N   1 
ATOM   5330 C CA  . GLY B 2 391 ? 63.566  79.712  104.141 1.00 133.94 ? 380 GLY B CA  1 
ATOM   5331 C C   . GLY B 2 391 ? 62.112  79.299  104.180 1.00 133.94 ? 380 GLY B C   1 
ATOM   5332 O O   . GLY B 2 391 ? 61.748  78.234  103.672 1.00 133.94 ? 380 GLY B O   1 
ATOM   5333 N N   . THR B 2 392 ? 61.269  80.132  104.782 1.00 138.19 ? 381 THR B N   1 
ATOM   5334 C CA  . THR B 2 392 ? 59.846  79.856  104.896 1.00 138.19 ? 381 THR B CA  1 
ATOM   5335 C C   . THR B 2 392 ? 59.051  81.007  104.301 1.00 138.19 ? 381 THR B C   1 
ATOM   5336 O O   . THR B 2 392 ? 59.494  82.159  104.325 1.00 138.19 ? 381 THR B O   1 
ATOM   5337 C CB  . THR B 2 392 ? 59.433  79.630  106.358 1.00 138.19 ? 381 THR B CB  1 
ATOM   5338 O OG1 . THR B 2 392 ? 58.040  79.301  106.418 1.00 138.19 ? 381 THR B OG1 1 
ATOM   5339 C CG2 . THR B 2 392 ? 59.696  80.870  107.192 1.00 138.19 ? 381 THR B CG2 1 
ATOM   5340 N N   . ASN B 2 393 ? 57.882  80.685  103.754 1.00 139.82 ? 382 ASN B N   1 
ATOM   5341 C CA  . ASN B 2 393 ? 56.989  81.689  103.193 1.00 139.82 ? 382 ASN B CA  1 
ATOM   5342 C C   . ASN B 2 393 ? 56.174  82.412  104.257 1.00 139.82 ? 382 ASN B C   1 
ATOM   5343 O O   . ASN B 2 393 ? 55.282  83.192  103.908 1.00 139.82 ? 382 ASN B O   1 
ATOM   5344 C CB  . ASN B 2 393 ? 56.052  81.046  102.167 1.00 139.82 ? 382 ASN B CB  1 
ATOM   5345 C CG  . ASN B 2 393 ? 54.929  80.257  102.813 1.00 139.82 ? 382 ASN B CG  1 
ATOM   5346 O OD1 . ASN B 2 393 ? 55.100  79.669  103.880 1.00 139.82 ? 382 ASN B OD1 1 
ATOM   5347 N ND2 . ASN B 2 393 ? 53.769  80.243  102.166 1.00 139.82 ? 382 ASN B ND2 1 
ATOM   5348 N N   . SER B 2 394 ? 56.453  82.165  105.534 1.00 139.09 ? 383 SER B N   1 
ATOM   5349 C CA  . SER B 2 394 ? 55.720  82.809  106.610 1.00 139.09 ? 383 SER B CA  1 
ATOM   5350 C C   . SER B 2 394 ? 55.923  84.320  106.576 1.00 139.09 ? 383 SER B C   1 
ATOM   5351 O O   . SER B 2 394 ? 56.878  84.838  105.992 1.00 139.09 ? 383 SER B O   1 
ATOM   5352 C CB  . SER B 2 394 ? 56.159  82.259  107.966 1.00 139.09 ? 383 SER B CB  1 
ATOM   5353 O OG  . SER B 2 394 ? 55.858  83.174  109.006 1.00 139.09 ? 383 SER B OG  1 
ATOM   5354 N N   . SER B 2 395 ? 55.003  85.030  107.223 1.00 135.82 ? 384 SER B N   1 
ATOM   5355 C CA  . SER B 2 395 ? 55.074  86.481  107.286 1.00 135.82 ? 384 SER B CA  1 
ATOM   5356 C C   . SER B 2 395 ? 54.815  87.037  108.678 1.00 135.82 ? 384 SER B C   1 
ATOM   5357 O O   . SER B 2 395 ? 54.863  88.259  108.849 1.00 135.82 ? 384 SER B O   1 
ATOM   5358 C CB  . SER B 2 395 ? 54.083  87.108  106.294 1.00 135.82 ? 384 SER B CB  1 
ATOM   5359 O OG  . SER B 2 395 ? 54.147  86.455  105.038 1.00 135.82 ? 384 SER B OG  1 
ATOM   5360 N N   . ASP B 2 396 ? 54.542  86.195  109.668 1.00 139.21 ? 385 ASP B N   1 
ATOM   5361 C CA  . ASP B 2 396 ? 54.309  86.634  111.034 1.00 139.21 ? 385 ASP B CA  1 
ATOM   5362 C C   . ASP B 2 396 ? 55.497  86.257  111.909 1.00 139.21 ? 385 ASP B C   1 
ATOM   5363 O O   . ASP B 2 396 ? 56.116  85.205  111.728 1.00 139.21 ? 385 ASP B O   1 
ATOM   5364 C CB  . ASP B 2 396 ? 53.019  86.027  111.595 1.00 139.21 ? 385 ASP B CB  1 
ATOM   5365 C CG  . ASP B 2 396 ? 53.106  84.523  111.765 1.00 139.21 ? 385 ASP B CG  1 
ATOM   5366 O OD1 . ASP B 2 396 ? 53.686  84.069  112.773 1.00 139.21 ? 385 ASP B OD1 1 
ATOM   5367 O OD2 . ASP B 2 396 ? 52.592  83.795  110.890 1.00 139.21 ? 385 ASP B OD2 1 
ATOM   5368 N N   . LEU B 2 397 ? 55.815  87.138  112.860 1.00 136.94 ? 386 LEU B N   1 
ATOM   5369 C CA  . LEU B 2 397 ? 56.956  86.923  113.741 1.00 136.94 ? 386 LEU B CA  1 
ATOM   5370 C C   . LEU B 2 397 ? 56.758  85.722  114.658 1.00 136.94 ? 386 LEU B C   1 
ATOM   5371 O O   . LEU B 2 397 ? 57.745  85.113  115.094 1.00 136.94 ? 386 LEU B O   1 
ATOM   5372 C CB  . LEU B 2 397 ? 57.206  88.183  114.571 1.00 136.94 ? 386 LEU B CB  1 
ATOM   5373 C CG  . LEU B 2 397 ? 58.363  88.176  115.568 1.00 136.94 ? 386 LEU B CG  1 
ATOM   5374 C CD1 . LEU B 2 397 ? 59.611  87.660  114.880 1.00 136.94 ? 386 LEU B CD1 1 
ATOM   5375 C CD2 . LEU B 2 397 ? 58.598  89.559  116.146 1.00 136.94 ? 386 LEU B CD2 1 
ATOM   5376 N N   . GLN B 2 398 ? 55.506  85.370  114.958 1.00 139.40 ? 387 GLN B N   1 
ATOM   5377 C CA  . GLN B 2 398 ? 55.240  84.276  115.885 1.00 139.40 ? 387 GLN B CA  1 
ATOM   5378 C C   . GLN B 2 398 ? 55.739  82.951  115.324 1.00 139.40 ? 387 GLN B C   1 
ATOM   5379 O O   . GLN B 2 398 ? 56.364  82.159  116.037 1.00 139.40 ? 387 GLN B O   1 
ATOM   5380 C CB  . GLN B 2 398 ? 53.745  84.205  116.197 1.00 139.40 ? 387 GLN B CB  1 
ATOM   5381 C CG  . GLN B 2 398 ? 53.101  85.548  116.519 1.00 139.40 ? 387 GLN B CG  1 
ATOM   5382 C CD  . GLN B 2 398 ? 54.013  86.465  117.313 1.00 139.40 ? 387 GLN B CD  1 
ATOM   5383 O OE1 . GLN B 2 398 ? 54.374  86.168  118.451 1.00 139.40 ? 387 GLN B OE1 1 
ATOM   5384 N NE2 . GLN B 2 398 ? 54.389  87.588  116.712 1.00 139.40 ? 387 GLN B NE2 1 
ATOM   5385 N N   . GLN B 2 399 ? 55.460  82.688  114.044 1.00 140.97 ? 388 GLN B N   1 
ATOM   5386 C CA  . GLN B 2 399 ? 56.009  81.498  113.402 1.00 140.97 ? 388 GLN B CA  1 
ATOM   5387 C C   . GLN B 2 399 ? 57.531  81.525  113.420 1.00 140.97 ? 388 GLN B C   1 
ATOM   5388 O O   . GLN B 2 399 ? 58.177  80.497  113.664 1.00 140.97 ? 388 GLN B O   1 
ATOM   5389 C CB  . GLN B 2 399 ? 55.490  81.383  111.969 1.00 140.97 ? 388 GLN B CB  1 
ATOM   5390 C CG  . GLN B 2 399 ? 54.019  81.020  111.867 1.00 140.97 ? 388 GLN B CG  1 
ATOM   5391 C CD  . GLN B 2 399 ? 53.702  79.678  112.497 1.00 140.97 ? 388 GLN B CD  1 
ATOM   5392 O OE1 . GLN B 2 399 ? 52.661  79.510  113.132 1.00 140.97 ? 388 GLN B OE1 1 
ATOM   5393 N NE2 . GLN B 2 399 ? 54.596  78.712  112.318 1.00 140.97 ? 388 GLN B NE2 1 
ATOM   5394 N N   . ILE B 2 400 ? 58.117  82.698  113.172 1.00 137.17 ? 389 ILE B N   1 
ATOM   5395 C CA  . ILE B 2 400 ? 59.572  82.836  113.175 1.00 137.17 ? 389 ILE B CA  1 
ATOM   5396 C C   . ILE B 2 400 ? 60.143  82.363  114.504 1.00 137.17 ? 389 ILE B C   1 
ATOM   5397 O O   . ILE B 2 400 ? 61.021  81.492  114.551 1.00 137.17 ? 389 ILE B O   1 
ATOM   5398 C CB  . ILE B 2 400 ? 59.969  84.292  112.877 1.00 137.17 ? 389 ILE B CB  1 
ATOM   5399 C CG1 . ILE B 2 400 ? 59.418  84.720  111.519 1.00 137.17 ? 389 ILE B CG1 1 
ATOM   5400 C CG2 . ILE B 2 400 ? 61.479  84.452  112.914 1.00 137.17 ? 389 ILE B CG2 1 
ATOM   5401 C CD1 . ILE B 2 400 ? 60.167  84.139  110.356 1.00 137.17 ? 389 ILE B CD1 1 
ATOM   5402 N N   . LEU B 2 401 ? 59.642  82.924  115.607 1.00 137.45 ? 390 LEU B N   1 
ATOM   5403 C CA  . LEU B 2 401 ? 60.135  82.515  116.919 1.00 137.45 ? 390 LEU B CA  1 
ATOM   5404 C C   . LEU B 2 401 ? 59.848  81.046  117.201 1.00 137.45 ? 390 LEU B C   1 
ATOM   5405 O O   . LEU B 2 401 ? 60.733  80.324  117.672 1.00 137.45 ? 390 LEU B O   1 
ATOM   5406 C CB  . LEU B 2 401 ? 59.545  83.397  118.019 1.00 137.45 ? 390 LEU B CB  1 
ATOM   5407 C CG  . LEU B 2 401 ? 60.410  84.570  118.480 1.00 137.45 ? 390 LEU B CG  1 
ATOM   5408 C CD1 . LEU B 2 401 ? 61.640  84.044  119.195 1.00 137.45 ? 390 LEU B CD1 1 
ATOM   5409 C CD2 . LEU B 2 401 ? 60.826  85.426  117.310 1.00 137.45 ? 390 LEU B CD2 1 
ATOM   5410 N N   . SER B 2 402 ? 58.629  80.577  116.914 1.00 139.48 ? 391 SER B N   1 
ATOM   5411 C CA  . SER B 2 402 ? 58.285  79.197  117.242 1.00 139.48 ? 391 SER B CA  1 
ATOM   5412 C C   . SER B 2 402 ? 59.183  78.204  116.517 1.00 139.48 ? 391 SER B C   1 
ATOM   5413 O O   . SER B 2 402 ? 59.461  77.121  117.044 1.00 139.48 ? 391 SER B O   1 
ATOM   5414 C CB  . SER B 2 402 ? 56.818  78.918  116.917 1.00 139.48 ? 391 SER B CB  1 
ATOM   5415 O OG  . SER B 2 402 ? 56.481  79.397  115.631 1.00 139.48 ? 391 SER B OG  1 
ATOM   5416 N N   . LEU B 2 403 ? 59.647  78.547  115.315 1.00 140.12 ? 392 LEU B N   1 
ATOM   5417 C CA  . LEU B 2 403 ? 60.620  77.695  114.642 1.00 140.12 ? 392 LEU B CA  1 
ATOM   5418 C C   . LEU B 2 403 ? 62.056  77.979  115.063 1.00 140.12 ? 392 LEU B C   1 
ATOM   5419 O O   . LEU B 2 403 ? 62.922  77.124  114.852 1.00 140.12 ? 392 LEU B O   1 
ATOM   5420 C CB  . LEU B 2 403 ? 60.502  77.831  113.121 1.00 140.12 ? 392 LEU B CB  1 
ATOM   5421 C CG  . LEU B 2 403 ? 59.097  77.801  112.521 1.00 140.12 ? 392 LEU B CG  1 
ATOM   5422 C CD1 . LEU B 2 403 ? 59.163  77.901  111.008 1.00 140.12 ? 392 LEU B CD1 1 
ATOM   5423 C CD2 . LEU B 2 403 ? 58.362  76.540  112.947 1.00 140.12 ? 392 LEU B CD2 1 
ATOM   5424 N N   . LEU B 2 404 ? 62.333  79.142  115.652 1.00 136.34 ? 393 LEU B N   1 
ATOM   5425 C CA  . LEU B 2 404 ? 63.694  79.533  115.995 1.00 136.34 ? 393 LEU B CA  1 
ATOM   5426 C C   . LEU B 2 404 ? 63.966  79.437  117.496 1.00 136.34 ? 393 LEU B C   1 
ATOM   5427 O O   . LEU B 2 404 ? 64.664  80.282  118.061 1.00 136.34 ? 393 LEU B O   1 
ATOM   5428 C CB  . LEU B 2 404 ? 63.977  80.946  115.488 1.00 136.34 ? 393 LEU B CB  1 
ATOM   5429 C CG  . LEU B 2 404 ? 65.437  81.306  115.203 1.00 136.34 ? 393 LEU B CG  1 
ATOM   5430 C CD1 . LEU B 2 404 ? 65.988  80.446  114.079 1.00 136.34 ? 393 LEU B CD1 1 
ATOM   5431 C CD2 . LEU B 2 404 ? 65.568  82.780  114.868 1.00 136.34 ? 393 LEU B CD2 1 
ATOM   5432 N N   . GLU B 2 405 ? 63.424  78.415  118.160 1.00 139.44 ? 394 GLU B N   1 
ATOM   5433 C CA  . GLU B 2 405 ? 63.673  78.236  119.589 1.00 139.44 ? 394 GLU B CA  1 
ATOM   5434 C C   . GLU B 2 405 ? 64.879  77.335  119.845 1.00 139.44 ? 394 GLU B C   1 
ATOM   5435 O O   . GLU B 2 405 ? 65.854  77.754  120.475 1.00 139.44 ? 394 GLU B O   1 
ATOM   5436 C CB  . GLU B 2 405 ? 62.430  77.666  120.284 1.00 139.44 ? 394 GLU B CB  1 
ATOM   5437 C CG  . GLU B 2 405 ? 61.159  78.471  120.081 1.00 139.44 ? 394 GLU B CG  1 
ATOM   5438 C CD  . GLU B 2 405 ? 61.164  79.799  120.820 1.00 139.44 ? 394 GLU B CD  1 
ATOM   5439 O OE1 . GLU B 2 405 ? 62.143  80.093  121.538 1.00 139.44 ? 394 GLU B OE1 1 
ATOM   5440 O OE2 . GLU B 2 405 ? 60.182  80.557  120.678 1.00 139.44 ? 394 GLU B OE2 1 
ATOM   5441 N N   . SER B 2 406 ? 64.820  76.092  119.368 1.00 139.18 ? 395 SER B N   1 
ATOM   5442 C CA  . SER B 2 406 ? 65.915  75.159  119.600 1.00 139.18 ? 395 SER B CA  1 
ATOM   5443 C C   . SER B 2 406 ? 67.135  75.485  118.749 1.00 139.18 ? 395 SER B C   1 
ATOM   5444 O O   . SER B 2 406 ? 68.247  75.058  119.080 1.00 139.18 ? 395 SER B O   1 
ATOM   5445 C CB  . SER B 2 406 ? 65.452  73.728  119.327 1.00 139.18 ? 395 SER B CB  1 
ATOM   5446 O OG  . SER B 2 406 ? 64.187  73.482  119.917 1.00 139.18 ? 395 SER B OG  1 
ATOM   5447 N N   . ASN B 2 407 ? 66.953  76.232  117.665 1.00 138.76 ? 396 ASN B N   1 
ATOM   5448 C CA  . ASN B 2 407 ? 68.032  76.561  116.743 1.00 138.76 ? 396 ASN B CA  1 
ATOM   5449 C C   . ASN B 2 407 ? 68.341  78.048  116.840 1.00 138.76 ? 396 ASN B C   1 
ATOM   5450 O O   . ASN B 2 407 ? 67.459  78.885  116.622 1.00 138.76 ? 396 ASN B O   1 
ATOM   5451 C CB  . ASN B 2 407 ? 67.651  76.178  115.315 1.00 138.76 ? 396 ASN B CB  1 
ATOM   5452 C CG  . ASN B 2 407 ? 67.607  74.682  115.113 1.00 138.76 ? 396 ASN B CG  1 
ATOM   5453 O OD1 . ASN B 2 407 ? 68.490  73.961  115.575 1.00 138.76 ? 396 ASN B OD1 1 
ATOM   5454 N ND2 . ASN B 2 407 ? 66.571  74.203  114.436 1.00 138.76 ? 396 ASN B ND2 1 
ATOM   5455 N N   . LYS B 2 408 ? 69.591  78.372  117.167 1.00 133.66 ? 397 LYS B N   1 
ATOM   5456 C CA  . LYS B 2 408 ? 70.025  79.752  117.308 1.00 133.66 ? 397 LYS B CA  1 
ATOM   5457 C C   . LYS B 2 408 ? 71.137  80.139  116.345 1.00 133.66 ? 397 LYS B C   1 
ATOM   5458 O O   . LYS B 2 408 ? 71.454  81.330  116.242 1.00 133.66 ? 397 LYS B O   1 
ATOM   5459 C CB  . LYS B 2 408 ? 70.492  80.022  118.749 1.00 133.66 ? 397 LYS B CB  1 
ATOM   5460 C CG  . LYS B 2 408 ? 69.562  79.493  119.847 1.00 133.66 ? 397 LYS B CG  1 
ATOM   5461 C CD  . LYS B 2 408 ? 68.088  79.834  119.628 1.00 133.66 ? 397 LYS B CD  1 
ATOM   5462 C CE  . LYS B 2 408 ? 67.856  81.333  119.519 1.00 133.66 ? 397 LYS B CE  1 
ATOM   5463 N NZ  . LYS B 2 408 ? 68.332  82.018  120.749 1.00 133.66 ? 397 LYS B NZ  1 
ATOM   5464 N N   . ASP B 2 409 ? 71.736  79.178  115.642 1.00 133.38 ? 398 ASP B N   1 
ATOM   5465 C CA  . ASP B 2 409 ? 72.729  79.443  114.610 1.00 133.38 ? 398 ASP B CA  1 
ATOM   5466 C C   . ASP B 2 409 ? 72.143  79.309  113.210 1.00 133.38 ? 398 ASP B C   1 
ATOM   5467 O O   . ASP B 2 409 ? 72.843  78.882  112.285 1.00 133.38 ? 398 ASP B O   1 
ATOM   5468 C CB  . ASP B 2 409 ? 73.927  78.508  114.777 1.00 133.38 ? 398 ASP B CB  1 
ATOM   5469 C CG  . ASP B 2 409 ? 74.426  78.452  116.207 1.00 133.38 ? 398 ASP B CG  1 
ATOM   5470 O OD1 . ASP B 2 409 ? 74.290  79.465  116.923 1.00 133.38 ? 398 ASP B OD1 1 
ATOM   5471 O OD2 . ASP B 2 409 ? 74.954  77.395  116.614 1.00 133.38 ? 398 ASP B OD2 1 
ATOM   5472 N N   . LEU B 2 410 ? 70.876  79.671  113.042 1.00 122.92 ? 399 LEU B N   1 
ATOM   5473 C CA  . LEU B 2 410 ? 70.104  79.385  111.840 1.00 122.92 ? 399 LEU B CA  1 
ATOM   5474 C C   . LEU B 2 410 ? 69.558  80.688  111.271 1.00 122.92 ? 399 LEU B C   1 
ATOM   5475 O O   . LEU B 2 410 ? 68.521  81.182  111.726 1.00 122.92 ? 399 LEU B O   1 
ATOM   5476 C CB  . LEU B 2 410 ? 68.966  78.425  112.169 1.00 122.92 ? 399 LEU B CB  1 
ATOM   5477 C CG  . LEU B 2 410 ? 68.081  77.941  111.029 1.00 122.92 ? 399 LEU B CG  1 
ATOM   5478 C CD1 . LEU B 2 410 ? 68.740  76.801  110.276 1.00 122.92 ? 399 LEU B CD1 1 
ATOM   5479 C CD2 . LEU B 2 410 ? 66.735  77.536  111.586 1.00 122.92 ? 399 LEU B CD2 1 
ATOM   5480 N N   . LEU B 2 411 ? 70.253  81.244  110.283 1.00 110.67 ? 400 LEU B N   1 
ATOM   5481 C CA  . LEU B 2 411 ? 69.738  82.407  109.571 1.00 110.67 ? 400 LEU B CA  1 
ATOM   5482 C C   . LEU B 2 411 ? 68.441  82.031  108.871 1.00 110.67 ? 400 LEU B C   1 
ATOM   5483 O O   . LEU B 2 411 ? 68.444  81.227  107.935 1.00 110.67 ? 400 LEU B O   1 
ATOM   5484 C CB  . LEU B 2 411 ? 70.763  82.909  108.562 1.00 110.67 ? 400 LEU B CB  1 
ATOM   5485 C CG  . LEU B 2 411 ? 72.219  82.849  109.007 1.00 110.67 ? 400 LEU B CG  1 
ATOM   5486 C CD1 . LEU B 2 411 ? 73.120  83.164  107.834 1.00 110.67 ? 400 LEU B CD1 1 
ATOM   5487 C CD2 . LEU B 2 411 ? 72.464  83.811  110.153 1.00 110.67 ? 400 LEU B CD2 1 
ATOM   5488 N N   . LEU B 2 412 ? 67.335  82.606  109.322 1.00 117.74 ? 401 LEU B N   1 
ATOM   5489 C CA  . LEU B 2 412 ? 66.007  82.244  108.837 1.00 117.74 ? 401 LEU B CA  1 
ATOM   5490 C C   . LEU B 2 412 ? 65.498  83.363  107.936 1.00 117.74 ? 401 LEU B C   1 
ATOM   5491 O O   . LEU B 2 412 ? 65.005  84.386  108.419 1.00 117.74 ? 401 LEU B O   1 
ATOM   5492 C CB  . LEU B 2 412 ? 65.064  81.991  110.008 1.00 117.74 ? 401 LEU B CB  1 
ATOM   5493 C CG  . LEU B 2 412 ? 63.649  81.527  109.676 1.00 117.74 ? 401 LEU B CG  1 
ATOM   5494 C CD1 . LEU B 2 412 ? 63.669  80.092  109.192 1.00 117.74 ? 401 LEU B CD1 1 
ATOM   5495 C CD2 . LEU B 2 412 ? 62.760  81.659  110.895 1.00 117.74 ? 401 LEU B CD2 1 
ATOM   5496 N N   . THR B 2 413 ? 65.623  83.168  106.626 1.00 118.14 ? 402 THR B N   1 
ATOM   5497 C CA  . THR B 2 413 ? 65.104  84.111  105.647 1.00 118.14 ? 402 THR B CA  1 
ATOM   5498 C C   . THR B 2 413 ? 63.632  83.816  105.399 1.00 118.14 ? 402 THR B C   1 
ATOM   5499 O O   . THR B 2 413 ? 63.268  82.683  105.072 1.00 118.14 ? 402 THR B O   1 
ATOM   5500 C CB  . THR B 2 413 ? 65.886  84.022  104.337 1.00 118.14 ? 402 THR B CB  1 
ATOM   5501 O OG1 . THR B 2 413 ? 65.698  82.726  103.758 1.00 118.14 ? 402 THR B OG1 1 
ATOM   5502 C CG2 . THR B 2 413 ? 67.363  84.245  104.584 1.00 118.14 ? 402 THR B CG2 1 
ATOM   5503 N N   . SER B 2 414 ? 62.788  84.831  105.557 1.00 128.18 ? 403 SER B N   1 
ATOM   5504 C CA  . SER B 2 414 ? 61.353  84.644  105.419 1.00 128.18 ? 403 SER B CA  1 
ATOM   5505 C C   . SER B 2 414 ? 60.735  85.902  104.827 1.00 128.18 ? 403 SER B C   1 
ATOM   5506 O O   . SER B 2 414 ? 61.401  86.926  104.652 1.00 128.18 ? 403 SER B O   1 
ATOM   5507 C CB  . SER B 2 414 ? 60.709  84.311  106.763 1.00 128.18 ? 403 SER B CB  1 
ATOM   5508 O OG  . SER B 2 414 ? 60.347  85.498  107.444 1.00 128.18 ? 403 SER B OG  1 
ATOM   5509 N N   . SER B 2 415 ? 59.442  85.817  104.532 1.00 132.50 ? 404 SER B N   1 
ATOM   5510 C CA  . SER B 2 415 ? 58.673  86.941  104.021 1.00 132.50 ? 404 SER B CA  1 
ATOM   5511 C C   . SER B 2 415 ? 58.180  87.862  105.125 1.00 132.50 ? 404 SER B C   1 
ATOM   5512 O O   . SER B 2 415 ? 57.227  88.616  104.905 1.00 132.50 ? 404 SER B O   1 
ATOM   5513 C CB  . SER B 2 415 ? 57.480  86.438  103.203 1.00 132.50 ? 404 SER B CB  1 
ATOM   5514 O OG  . SER B 2 415 ? 56.423  86.023  104.051 1.00 132.50 ? 404 SER B OG  1 
ATOM   5515 N N   . TYR B 2 416 ? 58.797  87.806  106.307 1.00 128.23 ? 405 TYR B N   1 
ATOM   5516 C CA  . TYR B 2 416 ? 58.397  88.640  107.432 1.00 128.23 ? 405 TYR B CA  1 
ATOM   5517 C C   . TYR B 2 416 ? 58.422  90.127  107.104 1.00 128.23 ? 405 TYR B C   1 
ATOM   5518 O O   . TYR B 2 416 ? 57.627  90.881  107.674 1.00 128.23 ? 405 TYR B O   1 
ATOM   5519 C CB  . TYR B 2 416 ? 59.306  88.337  108.626 1.00 128.23 ? 405 TYR B CB  1 
ATOM   5520 C CG  . TYR B 2 416 ? 59.255  89.351  109.742 1.00 128.23 ? 405 TYR B CG  1 
ATOM   5521 C CD1 . TYR B 2 416 ? 58.186  89.384  110.625 1.00 128.23 ? 405 TYR B CD1 1 
ATOM   5522 C CD2 . TYR B 2 416 ? 60.282  90.263  109.923 1.00 128.23 ? 405 TYR B CD2 1 
ATOM   5523 C CE1 . TYR B 2 416 ? 58.138  90.305  111.651 1.00 128.23 ? 405 TYR B CE1 1 
ATOM   5524 C CE2 . TYR B 2 416 ? 60.242  91.189  110.944 1.00 128.23 ? 405 TYR B CE2 1 
ATOM   5525 C CZ  . TYR B 2 416 ? 59.169  91.204  111.806 1.00 128.23 ? 405 TYR B CZ  1 
ATOM   5526 O OH  . TYR B 2 416 ? 59.125  92.126  112.825 1.00 128.23 ? 405 TYR B OH  1 
ATOM   5527 N N   . LEU B 2 417 ? 59.296  90.565  106.199 1.00 126.13 ? 406 LEU B N   1 
ATOM   5528 C CA  . LEU B 2 417 ? 59.380  91.966  105.802 1.00 126.13 ? 406 LEU B CA  1 
ATOM   5529 C C   . LEU B 2 417 ? 58.532  92.291  104.579 1.00 126.13 ? 406 LEU B C   1 
ATOM   5530 O O   . LEU B 2 417 ? 57.882  93.338  104.543 1.00 126.13 ? 406 LEU B O   1 
ATOM   5531 C CB  . LEU B 2 417 ? 60.835  92.355  105.525 1.00 126.13 ? 406 LEU B CB  1 
ATOM   5532 C CG  . LEU B 2 417 ? 61.801  92.349  106.703 1.00 126.13 ? 406 LEU B CG  1 
ATOM   5533 C CD1 . LEU B 2 417 ? 63.093  93.032  106.305 1.00 126.13 ? 406 LEU B CD1 1 
ATOM   5534 C CD2 . LEU B 2 417 ? 61.176  93.043  107.891 1.00 126.13 ? 406 LEU B CD2 1 
ATOM   5535 N N   . SER B 2 418 ? 58.537  91.414  103.571 1.00 130.32 ? 407 SER B N   1 
ATOM   5536 C CA  . SER B 2 418 ? 57.921  91.727  102.284 1.00 130.32 ? 407 SER B CA  1 
ATOM   5537 C C   . SER B 2 418 ? 56.452  92.108  102.401 1.00 130.32 ? 407 SER B C   1 
ATOM   5538 O O   . SER B 2 418 ? 55.943  92.832  101.540 1.00 130.32 ? 407 SER B O   1 
ATOM   5539 C CB  . SER B 2 418 ? 58.061  90.541  101.331 1.00 130.32 ? 407 SER B CB  1 
ATOM   5540 O OG  . SER B 2 418 ? 57.299  89.435  101.782 1.00 130.32 ? 407 SER B OG  1 
ATOM   5541 N N   . ASP B 2 419 ? 55.758  91.643  103.442 1.00 133.28 ? 408 ASP B N   1 
ATOM   5542 C CA  . ASP B 2 419 ? 54.351  91.987  103.603 1.00 133.28 ? 408 ASP B CA  1 
ATOM   5543 C C   . ASP B 2 419 ? 54.146  93.457  103.952 1.00 133.28 ? 408 ASP B C   1 
ATOM   5544 O O   . ASP B 2 419 ? 52.998  93.893  104.092 1.00 133.28 ? 408 ASP B O   1 
ATOM   5545 C CB  . ASP B 2 419 ? 53.717  91.103  104.677 1.00 133.28 ? 408 ASP B CB  1 
ATOM   5546 C CG  . ASP B 2 419 ? 52.218  90.975  104.514 1.00 133.28 ? 408 ASP B CG  1 
ATOM   5547 O OD1 . ASP B 2 419 ? 51.750  90.896  103.359 1.00 133.28 ? 408 ASP B OD1 1 
ATOM   5548 O OD2 . ASP B 2 419 ? 51.506  90.958  105.540 1.00 133.28 ? 408 ASP B OD2 1 
ATOM   5549 N N   . SER B 2 420 ? 55.225  94.224  104.096 1.00 134.91 ? 409 SER B N   1 
ATOM   5550 C CA  . SER B 2 420 ? 55.121  95.615  104.516 1.00 134.91 ? 409 SER B CA  1 
ATOM   5551 C C   . SER B 2 420 ? 54.367  96.451  103.490 1.00 134.91 ? 409 SER B C   1 
ATOM   5552 O O   . SER B 2 420 ? 54.440  96.203  102.283 1.00 134.91 ? 409 SER B O   1 
ATOM   5553 C CB  . SER B 2 420 ? 56.516  96.205  104.736 1.00 134.91 ? 409 SER B CB  1 
ATOM   5554 O OG  . SER B 2 420 ? 57.046  96.718  103.526 1.00 134.91 ? 409 SER B OG  1 
ATOM   5555 N N   . GLY B 2 421 ? 53.634  97.444  103.987 1.00 139.54 ? 410 GLY B N   1 
ATOM   5556 C CA  . GLY B 2 421 ? 53.019  98.444  103.139 1.00 139.54 ? 410 GLY B CA  1 
ATOM   5557 C C   . GLY B 2 421 ? 53.923  99.646  102.960 1.00 139.54 ? 410 GLY B C   1 
ATOM   5558 O O   . GLY B 2 421 ? 53.468  100.731 102.586 1.00 139.54 ? 410 GLY B O   1 
ATOM   5559 N N   . SER B 2 422 ? 55.217  99.451  103.229 1.00 140.97 ? 411 SER B N   1 
ATOM   5560 C CA  . SER B 2 422 ? 56.247  100.486 103.098 1.00 140.97 ? 411 SER B CA  1 
ATOM   5561 C C   . SER B 2 422 ? 55.917  101.735 103.911 1.00 140.97 ? 411 SER B C   1 
ATOM   5562 O O   . SER B 2 422 ? 56.195  102.858 103.484 1.00 140.97 ? 411 SER B O   1 
ATOM   5563 C CB  . SER B 2 422 ? 56.498  100.858 101.632 1.00 140.97 ? 411 SER B CB  1 
ATOM   5564 O OG  . SER B 2 422 ? 55.296  101.071 100.912 1.00 140.97 ? 411 SER B OG  1 
ATOM   5565 N N   . THR B 2 423 ? 55.326  101.554 105.088 1.00 139.69 ? 412 THR B N   1 
ATOM   5566 C CA  . THR B 2 423 ? 55.047  102.654 106.001 1.00 139.69 ? 412 THR B CA  1 
ATOM   5567 C C   . THR B 2 423 ? 56.180  102.761 107.012 1.00 139.69 ? 412 THR B C   1 
ATOM   5568 O O   . THR B 2 423 ? 56.532  101.770 107.661 1.00 139.69 ? 412 THR B O   1 
ATOM   5569 C CB  . THR B 2 423 ? 53.710  102.450 106.715 1.00 139.69 ? 412 THR B CB  1 
ATOM   5570 O OG1 . THR B 2 423 ? 52.635  102.744 105.815 1.00 139.69 ? 412 THR B OG1 1 
ATOM   5571 C CG2 . THR B 2 423 ? 53.609  103.359 107.933 1.00 139.69 ? 412 THR B CG2 1 
ATOM   5572 N N   . GLY B 2 424 ? 56.753  103.959 107.132 1.00 135.98 ? 413 GLY B N   1 
ATOM   5573 C CA  . GLY B 2 424 ? 57.876  104.201 108.019 1.00 135.98 ? 413 GLY B CA  1 
ATOM   5574 C C   . GLY B 2 424 ? 57.667  103.698 109.430 1.00 135.98 ? 413 GLY B C   1 
ATOM   5575 O O   . GLY B 2 424 ? 58.505  102.967 109.967 1.00 135.98 ? 413 GLY B O   1 
ATOM   5576 N N   . GLU B 2 425 ? 56.547  104.076 110.040 1.00 139.24 ? 414 GLU B N   1 
ATOM   5577 C CA  . GLU B 2 425 ? 56.202  103.564 111.358 1.00 139.24 ? 414 GLU B CA  1 
ATOM   5578 C C   . GLU B 2 425 ? 55.980  102.060 111.352 1.00 139.24 ? 414 GLU B C   1 
ATOM   5579 O O   . GLU B 2 425 ? 56.401  101.375 112.293 1.00 139.24 ? 414 GLU B O   1 
ATOM   5580 C CB  . GLU B 2 425 ? 54.951  104.271 111.886 1.00 139.24 ? 414 GLU B CB  1 
ATOM   5581 C CG  . GLU B 2 425 ? 55.245  105.548 112.656 1.00 139.24 ? 414 GLU B CG  1 
ATOM   5582 C CD  . GLU B 2 425 ? 55.400  106.753 111.749 1.00 139.24 ? 414 GLU B CD  1 
ATOM   5583 O OE1 . GLU B 2 425 ? 54.628  106.870 110.774 1.00 139.24 ? 414 GLU B OE1 1 
ATOM   5584 O OE2 . GLU B 2 425 ? 56.298  107.581 112.008 1.00 139.24 ? 414 GLU B OE2 1 
ATOM   5585 N N   . HIS B 2 426 ? 55.346  101.532 110.303 1.00 135.34 ? 415 HIS B N   1 
ATOM   5586 C CA  . HIS B 2 426 ? 55.101  100.095 110.225 1.00 135.34 ? 415 HIS B CA  1 
ATOM   5587 C C   . HIS B 2 426 ? 56.409  99.316  110.170 1.00 135.34 ? 415 HIS B C   1 
ATOM   5588 O O   . HIS B 2 426 ? 56.624  98.395  110.965 1.00 135.34 ? 415 HIS B O   1 
ATOM   5589 C CB  . HIS B 2 426 ? 54.233  99.776  109.009 1.00 135.34 ? 415 HIS B CB  1 
ATOM   5590 C CG  . HIS B 2 426 ? 53.863  98.331  108.893 1.00 135.34 ? 415 HIS B CG  1 
ATOM   5591 N ND1 . HIS B 2 426 ? 53.438  97.765  107.711 1.00 135.34 ? 415 HIS B ND1 1 
ATOM   5592 C CD2 . HIS B 2 426 ? 53.852  97.337  109.813 1.00 135.34 ? 415 HIS B CD2 1 
ATOM   5593 C CE1 . HIS B 2 426 ? 53.182  96.483  107.907 1.00 135.34 ? 415 HIS B CE1 1 
ATOM   5594 N NE2 . HIS B 2 426 ? 53.425  96.199  109.174 1.00 135.34 ? 415 HIS B NE2 1 
ATOM   5595 N N   . THR B 2 427 ? 57.296  99.671  109.238 1.00 132.16 ? 416 THR B N   1 
ATOM   5596 C CA  . THR B 2 427 ? 58.565  98.958  109.132 1.00 132.16 ? 416 THR B CA  1 
ATOM   5597 C C   . THR B 2 427 ? 59.450  99.201  110.348 1.00 132.16 ? 416 THR B C   1 
ATOM   5598 O O   . THR B 2 427 ? 60.210  98.310  110.744 1.00 132.16 ? 416 THR B O   1 
ATOM   5599 C CB  . THR B 2 427 ? 59.294  99.353  107.845 1.00 132.16 ? 416 THR B CB  1 
ATOM   5600 O OG1 . THR B 2 427 ? 60.467  98.545  107.691 1.00 132.16 ? 416 THR B OG1 1 
ATOM   5601 C CG2 . THR B 2 427 ? 59.690  100.820 107.864 1.00 132.16 ? 416 THR B CG2 1 
ATOM   5602 N N   . LYS B 2 428 ? 59.353  100.382 110.963 1.00 128.57 ? 417 LYS B N   1 
ATOM   5603 C CA  . LYS B 2 428 ? 60.089  100.637 112.196 1.00 128.57 ? 417 LYS B CA  1 
ATOM   5604 C C   . LYS B 2 428 ? 59.655  99.676  113.291 1.00 128.57 ? 417 LYS B C   1 
ATOM   5605 O O   . LYS B 2 428 ? 60.485  98.974  113.886 1.00 128.57 ? 417 LYS B O   1 
ATOM   5606 C CB  . LYS B 2 428 ? 59.880  102.087 112.636 1.00 128.57 ? 417 LYS B CB  1 
ATOM   5607 C CG  . LYS B 2 428 ? 60.794  102.539 113.764 1.00 128.57 ? 417 LYS B CG  1 
ATOM   5608 C CD  . LYS B 2 428 ? 60.932  104.054 113.788 1.00 128.57 ? 417 LYS B CD  1 
ATOM   5609 C CE  . LYS B 2 428 ? 62.009  104.499 114.762 1.00 128.57 ? 417 LYS B CE  1 
ATOM   5610 N NZ  . LYS B 2 428 ? 62.563  105.832 114.402 1.00 128.57 ? 417 LYS B NZ  1 
ATOM   5611 N N   . SER B 2 429 ? 58.351  99.644  113.579 1.00 130.88 ? 418 SER B N   1 
ATOM   5612 C CA  . SER B 2 429 ? 57.820  98.690  114.544 1.00 130.88 ? 418 SER B CA  1 
ATOM   5613 C C   . SER B 2 429 ? 58.211  97.266  114.180 1.00 130.88 ? 418 SER B C   1 
ATOM   5614 O O   . SER B 2 429 ? 58.567  96.475  115.055 1.00 130.88 ? 418 SER B O   1 
ATOM   5615 C CB  . SER B 2 429 ? 56.300  98.824  114.628 1.00 130.88 ? 418 SER B CB  1 
ATOM   5616 O OG  . SER B 2 429 ? 55.703  98.644  113.355 1.00 130.88 ? 418 SER B OG  1 
ATOM   5617 N N   . LEU B 2 430 ? 58.193  96.935  112.888 1.00 128.67 ? 419 LEU B N   1 
ATOM   5618 C CA  . LEU B 2 430 ? 58.444  95.561  112.465 1.00 128.67 ? 419 LEU B CA  1 
ATOM   5619 C C   . LEU B 2 430 ? 59.878  95.141  112.767 1.00 128.67 ? 419 LEU B C   1 
ATOM   5620 O O   . LEU B 2 430 ? 60.114  94.114  113.414 1.00 128.67 ? 419 LEU B O   1 
ATOM   5621 C CB  . LEU B 2 430 ? 58.138  95.422  110.974 1.00 128.67 ? 419 LEU B CB  1 
ATOM   5622 C CG  . LEU B 2 430 ? 57.856  94.018  110.448 1.00 128.67 ? 419 LEU B CG  1 
ATOM   5623 C CD1 . LEU B 2 430 ? 56.600  93.461  111.095 1.00 128.67 ? 419 LEU B CD1 1 
ATOM   5624 C CD2 . LEU B 2 430 ? 57.715  94.038  108.937 1.00 128.67 ? 419 LEU B CD2 1 
ATOM   5625 N N   . VAL B 2 431 ? 60.851  95.929  112.307 1.00 121.44 ? 420 VAL B N   1 
ATOM   5626 C CA  . VAL B 2 431 ? 62.253  95.586  112.537 1.00 121.44 ? 420 VAL B CA  1 
ATOM   5627 C C   . VAL B 2 431 ? 62.576  95.618  114.026 1.00 121.44 ? 420 VAL B C   1 
ATOM   5628 O O   . VAL B 2 431 ? 63.238  94.714  114.555 1.00 121.44 ? 420 VAL B O   1 
ATOM   5629 C CB  . VAL B 2 431 ? 63.178  96.521  111.738 1.00 121.44 ? 420 VAL B CB  1 
ATOM   5630 C CG1 . VAL B 2 431 ? 64.617  96.069  111.870 1.00 121.44 ? 420 VAL B CG1 1 
ATOM   5631 C CG2 . VAL B 2 431 ? 62.770  96.537  110.280 1.00 121.44 ? 420 VAL B CG2 1 
ATOM   5632 N N   . THR B 2 432 ? 62.125  96.665  114.727 1.00 123.14 ? 421 THR B N   1 
ATOM   5633 C CA  . THR B 2 432 ? 62.427  96.771  116.151 1.00 123.14 ? 421 THR B CA  1 
ATOM   5634 C C   . THR B 2 432 ? 61.807  95.624  116.939 1.00 123.14 ? 421 THR B C   1 
ATOM   5635 O O   . THR B 2 432 ? 62.418  95.113  117.882 1.00 123.14 ? 421 THR B O   1 
ATOM   5636 C CB  . THR B 2 432 ? 61.952  98.118  116.694 1.00 123.14 ? 421 THR B CB  1 
ATOM   5637 O OG1 . THR B 2 432 ? 60.550  98.273  116.440 1.00 123.14 ? 421 THR B OG1 1 
ATOM   5638 C CG2 . THR B 2 432 ? 62.723  99.259  116.046 1.00 123.14 ? 421 THR B CG2 1 
ATOM   5639 N N   . GLN B 2 433 ? 60.604  95.189  116.556 1.00 125.99 ? 422 GLN B N   1 
ATOM   5640 C CA  . GLN B 2 433 ? 59.956  94.088  117.255 1.00 125.99 ? 422 GLN B CA  1 
ATOM   5641 C C   . GLN B 2 433 ? 60.638  92.765  116.946 1.00 125.99 ? 422 GLN B C   1 
ATOM   5642 O O   . GLN B 2 433 ? 60.764  91.908  117.826 1.00 125.99 ? 422 GLN B O   1 
ATOM   5643 C CB  . GLN B 2 433 ? 58.476  94.036  116.877 1.00 125.99 ? 422 GLN B CB  1 
ATOM   5644 C CG  . GLN B 2 433 ? 57.735  92.822  117.401 1.00 125.99 ? 422 GLN B CG  1 
ATOM   5645 C CD  . GLN B 2 433 ? 56.388  92.638  116.735 1.00 125.99 ? 422 GLN B CD  1 
ATOM   5646 O OE1 . GLN B 2 433 ? 55.527  91.917  117.238 1.00 125.99 ? 422 GLN B OE1 1 
ATOM   5647 N NE2 . GLN B 2 433 ? 56.199  93.291  115.595 1.00 125.99 ? 422 GLN B NE2 1 
ATOM   5648 N N   . TYR B 2 434 ? 61.090  92.580  115.703 1.00 120.93 ? 423 TYR B N   1 
ATOM   5649 C CA  . TYR B 2 434 ? 61.845  91.376  115.378 1.00 120.93 ? 423 TYR B CA  1 
ATOM   5650 C C   . TYR B 2 434 ? 63.120  91.302  116.203 1.00 120.93 ? 423 TYR B C   1 
ATOM   5651 O O   . TYR B 2 434 ? 63.481  90.238  116.716 1.00 120.93 ? 423 TYR B O   1 
ATOM   5652 C CB  . TYR B 2 434 ? 62.173  91.337  113.886 1.00 120.93 ? 423 TYR B CB  1 
ATOM   5653 C CG  . TYR B 2 434 ? 62.892  90.074  113.459 1.00 120.93 ? 423 TYR B CG  1 
ATOM   5654 C CD1 . TYR B 2 434 ? 64.275  89.982  113.520 1.00 120.93 ? 423 TYR B CD1 1 
ATOM   5655 C CD2 . TYR B 2 434 ? 62.186  88.977  112.993 1.00 120.93 ? 423 TYR B CD2 1 
ATOM   5656 C CE1 . TYR B 2 434 ? 64.931  88.833  113.133 1.00 120.93 ? 423 TYR B CE1 1 
ATOM   5657 C CE2 . TYR B 2 434 ? 62.835  87.823  112.604 1.00 120.93 ? 423 TYR B CE2 1 
ATOM   5658 C CZ  . TYR B 2 434 ? 64.207  87.757  112.675 1.00 120.93 ? 423 TYR B CZ  1 
ATOM   5659 O OH  . TYR B 2 434 ? 64.860  86.611  112.287 1.00 120.93 ? 423 TYR B OH  1 
ATOM   5660 N N   . LEU B 2 435 ? 63.815  92.430  116.347 1.00 116.41 ? 424 LEU B N   1 
ATOM   5661 C CA  . LEU B 2 435 ? 65.064  92.410  117.101 1.00 116.41 ? 424 LEU B CA  1 
ATOM   5662 C C   . LEU B 2 435 ? 64.825  92.260  118.599 1.00 116.41 ? 424 LEU B C   1 
ATOM   5663 O O   . LEU B 2 435 ? 65.546  91.507  119.264 1.00 116.41 ? 424 LEU B O   1 
ATOM   5664 C CB  . LEU B 2 435 ? 65.879  93.665  116.804 1.00 116.41 ? 424 LEU B CB  1 
ATOM   5665 C CG  . LEU B 2 435 ? 66.610  93.604  115.465 1.00 116.41 ? 424 LEU B CG  1 
ATOM   5666 C CD1 . LEU B 2 435 ? 67.320  94.907  115.193 1.00 116.41 ? 424 LEU B CD1 1 
ATOM   5667 C CD2 . LEU B 2 435 ? 67.594  92.450  115.456 1.00 116.41 ? 424 LEU B CD2 1 
ATOM   5668 N N   . ASN B 2 436 ? 63.829  92.959  119.150 1.00 121.90 ? 425 ASN B N   1 
ATOM   5669 C CA  . ASN B 2 436 ? 63.520  92.810  120.568 1.00 121.90 ? 425 ASN B CA  1 
ATOM   5670 C C   . ASN B 2 436 ? 63.009  91.411  120.886 1.00 121.90 ? 425 ASN B C   1 
ATOM   5671 O O   . ASN B 2 436 ? 63.192  90.926  122.008 1.00 121.90 ? 425 ASN B O   1 
ATOM   5672 C CB  . ASN B 2 436 ? 62.494  93.859  120.996 1.00 121.90 ? 425 ASN B CB  1 
ATOM   5673 C CG  . ASN B 2 436 ? 62.150  93.770  122.471 1.00 121.90 ? 425 ASN B CG  1 
ATOM   5674 O OD1 . ASN B 2 436 ? 63.016  93.519  123.308 1.00 121.90 ? 425 ASN B OD1 1 
ATOM   5675 N ND2 . ASN B 2 436 ? 60.879  93.975  122.795 1.00 121.90 ? 425 ASN B ND2 1 
ATOM   5676 N N   . ALA B 2 437 ? 62.373  90.749  119.919 1.00 117.80 ? 426 ALA B N   1 
ATOM   5677 C CA  . ALA B 2 437 ? 61.923  89.381  120.130 1.00 117.80 ? 426 ALA B CA  1 
ATOM   5678 C C   . ALA B 2 437 ? 63.082  88.397  120.110 1.00 117.80 ? 426 ALA B C   1 
ATOM   5679 O O   . ALA B 2 437 ? 63.070  87.416  120.860 1.00 117.80 ? 426 ALA B O   1 
ATOM   5680 C CB  . ALA B 2 437 ? 60.887  88.997  119.072 1.00 117.80 ? 426 ALA B CB  1 
ATOM   5681 N N   . THR B 2 438 ? 64.081  88.636  119.267 1.00 115.53 ? 427 THR B N   1 
ATOM   5682 C CA  . THR B 2 438 ? 65.281  87.815  119.247 1.00 115.53 ? 427 THR B CA  1 
ATOM   5683 C C   . THR B 2 438 ? 66.395  88.393  120.108 1.00 115.53 ? 427 THR B C   1 
ATOM   5684 O O   . THR B 2 438 ? 67.494  87.832  120.132 1.00 115.53 ? 427 THR B O   1 
ATOM   5685 C CB  . THR B 2 438 ? 65.783  87.637  117.811 1.00 115.53 ? 427 THR B CB  1 
ATOM   5686 O OG1 . THR B 2 438 ? 66.827  86.657  117.788 1.00 115.53 ? 427 THR B OG1 1 
ATOM   5687 C CG2 . THR B 2 438 ? 66.330  88.948  117.281 1.00 115.53 ? 427 THR B CG2 1 
ATOM   5688 N N   . GLY B 2 439 ? 66.142  89.499  120.799 1.00 114.05 ? 428 GLY B N   1 
ATOM   5689 C CA  . GLY B 2 439 ? 67.122  90.047  121.724 1.00 114.05 ? 428 GLY B CA  1 
ATOM   5690 C C   . GLY B 2 439 ? 68.422  90.471  121.080 1.00 114.05 ? 428 GLY B C   1 
ATOM   5691 O O   . GLY B 2 439 ? 69.500  90.157  121.601 1.00 114.05 ? 428 GLY B O   1 
ATOM   5692 N N   . ASN B 2 440 ? 68.346  91.179  119.953 1.00 109.40 ? 429 ASN B N   1 
ATOM   5693 C CA  . ASN B 2 440 ? 69.528  91.693  119.260 1.00 109.40 ? 429 ASN B CA  1 
ATOM   5694 C C   . ASN B 2 440 ? 70.497  90.571  118.894 1.00 109.40 ? 429 ASN B C   1 
ATOM   5695 O O   . ASN B 2 440 ? 71.716  90.720  118.998 1.00 109.40 ? 429 ASN B O   1 
ATOM   5696 C CB  . ASN B 2 440 ? 70.232  92.769  120.092 1.00 109.40 ? 429 ASN B CB  1 
ATOM   5697 C CG  . ASN B 2 440 ? 69.519  94.105  120.039 1.00 109.40 ? 429 ASN B CG  1 
ATOM   5698 O OD1 . ASN B 2 440 ? 68.597  94.361  120.813 1.00 109.40 ? 429 ASN B OD1 1 
ATOM   5699 N ND2 . ASN B 2 440 ? 69.944  94.968  119.123 1.00 109.40 ? 429 ASN B ND2 1 
ATOM   5700 N N   . ARG B 2 441 ? 69.953  89.439  118.460 1.00 107.98 ? 430 ARG B N   1 
ATOM   5701 C CA  . ARG B 2 441 ? 70.772  88.326  118.002 1.00 107.98 ? 430 ARG B CA  1 
ATOM   5702 C C   . ARG B 2 441 ? 71.226  88.605  116.570 1.00 107.98 ? 430 ARG B C   1 
ATOM   5703 O O   . ARG B 2 441 ? 71.092  89.719  116.057 1.00 107.98 ? 430 ARG B O   1 
ATOM   5704 C CB  . ARG B 2 441 ? 70.000  87.014  118.124 1.00 107.98 ? 430 ARG B CB  1 
ATOM   5705 C CG  . ARG B 2 441 ? 70.880  85.801  118.382 1.00 107.98 ? 430 ARG B CG  1 
ATOM   5706 C CD  . ARG B 2 441 ? 70.079  84.614  118.890 1.00 107.98 ? 430 ARG B CD  1 
ATOM   5707 N NE  . ARG B 2 441 ? 69.383  84.908  120.137 1.00 107.98 ? 430 ARG B NE  1 
ATOM   5708 C CZ  . ARG B 2 441 ? 68.062  84.970  120.255 1.00 107.98 ? 430 ARG B CZ  1 
ATOM   5709 N NH1 . ARG B 2 441 ? 67.290  84.755  119.200 1.00 107.98 ? 430 ARG B NH1 1 
ATOM   5710 N NH2 . ARG B 2 441 ? 67.512  85.244  121.430 1.00 107.98 ? 430 ARG B NH2 1 
ATOM   5711 N N   . TRP B 2 442 ? 71.782  87.598  115.905 1.00 98.53  ? 431 TRP B N   1 
ATOM   5712 C CA  . TRP B 2 442 ? 72.222  87.734  114.523 1.00 98.53  ? 431 TRP B CA  1 
ATOM   5713 C C   . TRP B 2 442 ? 71.192  87.094  113.602 1.00 98.53  ? 431 TRP B C   1 
ATOM   5714 O O   . TRP B 2 442 ? 70.958  85.882  113.671 1.00 98.53  ? 431 TRP B O   1 
ATOM   5715 C CB  . TRP B 2 442 ? 73.590  87.092  114.319 1.00 98.53  ? 431 TRP B CB  1 
ATOM   5716 C CG  . TRP B 2 442 ? 74.162  87.401  112.986 1.00 98.53  ? 431 TRP B CG  1 
ATOM   5717 C CD1 . TRP B 2 442 ? 74.114  86.618  111.879 1.00 98.53  ? 431 TRP B CD1 1 
ATOM   5718 C CD2 . TRP B 2 442 ? 74.865  88.589  112.612 1.00 98.53  ? 431 TRP B CD2 1 
ATOM   5719 N NE1 . TRP B 2 442 ? 74.745  87.241  110.834 1.00 98.53  ? 431 TRP B NE1 1 
ATOM   5720 C CE2 . TRP B 2 442 ? 75.218  88.453  111.260 1.00 98.53  ? 431 TRP B CE2 1 
ATOM   5721 C CE3 . TRP B 2 442 ? 75.233  89.754  113.291 1.00 98.53  ? 431 TRP B CE3 1 
ATOM   5722 C CZ2 . TRP B 2 442 ? 75.919  89.437  110.570 1.00 98.53  ? 431 TRP B CZ2 1 
ATOM   5723 C CZ3 . TRP B 2 442 ? 75.931  90.729  112.605 1.00 98.53  ? 431 TRP B CZ3 1 
ATOM   5724 C CH2 . TRP B 2 442 ? 76.266  90.565  111.259 1.00 98.53  ? 431 TRP B CH2 1 
ATOM   5725 N N   . CYS B 2 443 ? 70.585  87.902  112.743 1.00 103.79 ? 432 CYS B N   1 
ATOM   5726 C CA  . CYS B 2 443 ? 69.485  87.473  111.893 1.00 103.79 ? 432 CYS B CA  1 
ATOM   5727 C C   . CYS B 2 443 ? 69.860  87.614  110.420 1.00 103.79 ? 432 CYS B C   1 
ATOM   5728 O O   . CYS B 2 443 ? 70.967  88.029  110.065 1.00 103.79 ? 432 CYS B O   1 
ATOM   5729 C CB  . CYS B 2 443 ? 68.223  88.274  112.213 1.00 103.79 ? 432 CYS B CB  1 
ATOM   5730 S SG  . CYS B 2 443 ? 68.517  90.044  112.394 1.00 103.79 ? 432 CYS B SG  1 
ATOM   5731 N N   . SER B 2 444 ? 68.914  87.259  109.557 1.00 100.94 ? 433 SER B N   1 
ATOM   5732 C CA  . SER B 2 444 ? 69.080  87.341  108.114 1.00 100.94 ? 433 SER B CA  1 
ATOM   5733 C C   . SER B 2 444 ? 67.960  88.190  107.541 1.00 100.94 ? 433 SER B C   1 
ATOM   5734 O O   . SER B 2 444 ? 66.781  87.895  107.757 1.00 100.94 ? 433 SER B O   1 
ATOM   5735 C CB  . SER B 2 444 ? 69.060  85.954  107.480 1.00 100.94 ? 433 SER B CB  1 
ATOM   5736 O OG  . SER B 2 444 ? 67.780  85.368  107.624 1.00 100.94 ? 433 SER B OG  1 
ATOM   5737 N N   . TRP B 2 445 ? 68.328  89.229  106.801 1.00 99.13  ? 434 TRP B N   1 
ATOM   5738 C CA  . TRP B 2 445 ? 67.381  90.221  106.304 1.00 99.13  ? 434 TRP B CA  1 
ATOM   5739 C C   . TRP B 2 445 ? 67.161  90.020  104.812 1.00 99.13  ? 434 TRP B C   1 
ATOM   5740 O O   . TRP B 2 445 ? 68.065  90.259  104.005 1.00 99.13  ? 434 TRP B O   1 
ATOM   5741 C CB  . TRP B 2 445 ? 67.878  91.631  106.600 1.00 99.13  ? 434 TRP B CB  1 
ATOM   5742 C CG  . TRP B 2 445 ? 67.818  91.959  108.044 1.00 99.13  ? 434 TRP B CG  1 
ATOM   5743 C CD1 . TRP B 2 445 ? 68.855  92.319  108.842 1.00 99.13  ? 434 TRP B CD1 1 
ATOM   5744 C CD2 . TRP B 2 445 ? 66.654  91.949  108.877 1.00 99.13  ? 434 TRP B CD2 1 
ATOM   5745 N NE1 . TRP B 2 445 ? 68.413  92.542  110.121 1.00 99.13  ? 434 TRP B NE1 1 
ATOM   5746 C CE2 . TRP B 2 445 ? 67.063  92.320  110.167 1.00 99.13  ? 434 TRP B CE2 1 
ATOM   5747 C CE3 . TRP B 2 445 ? 65.305  91.665  108.654 1.00 99.13  ? 434 TRP B CE3 1 
ATOM   5748 C CZ2 . TRP B 2 445 ? 66.176  92.413  111.231 1.00 99.13  ? 434 TRP B CZ2 1 
ATOM   5749 C CZ3 . TRP B 2 445 ? 64.427  91.758  109.710 1.00 99.13  ? 434 TRP B CZ3 1 
ATOM   5750 C CH2 . TRP B 2 445 ? 64.864  92.129  110.982 1.00 99.13  ? 434 TRP B CH2 1 
ATOM   5751 N N   . SER B 2 446 ? 65.958  89.588  104.454 1.00 106.76 ? 435 SER B N   1 
ATOM   5752 C CA  . SER B 2 446 ? 65.572  89.429  103.060 1.00 106.76 ? 435 SER B CA  1 
ATOM   5753 C C   . SER B 2 446 ? 64.056  89.471  102.987 1.00 106.76 ? 435 SER B C   1 
ATOM   5754 O O   . SER B 2 446 ? 63.364  89.401  104.005 1.00 106.76 ? 435 SER B O   1 
ATOM   5755 C CB  . SER B 2 446 ? 66.111  88.126  102.471 1.00 106.76 ? 435 SER B CB  1 
ATOM   5756 O OG  . SER B 2 446 ? 65.683  87.967  101.130 1.00 106.76 ? 435 SER B OG  1 
ATOM   5757 N N   . LEU B 2 447 ? 63.544  89.576  101.764 1.00 120.27 ? 436 LEU B N   1 
ATOM   5758 C CA  . LEU B 2 447 ? 62.106  89.667  101.566 1.00 120.27 ? 436 LEU B CA  1 
ATOM   5759 C C   . LEU B 2 447 ? 61.444  88.316  101.347 1.00 120.27 ? 436 LEU B C   1 
ATOM   5760 O O   . LEU B 2 447 ? 60.231  88.202  101.552 1.00 120.27 ? 436 LEU B O   1 
ATOM   5761 C CB  . LEU B 2 447 ? 61.789  90.590  100.389 1.00 120.27 ? 436 LEU B CB  1 
ATOM   5762 C CG  . LEU B 2 447 ? 62.267  92.032  100.557 1.00 120.27 ? 436 LEU B CG  1 
ATOM   5763 C CD1 . LEU B 2 447 ? 61.637  92.919  99.502  1.00 120.27 ? 436 LEU B CD1 1 
ATOM   5764 C CD2 . LEU B 2 447 ? 61.951  92.546  101.947 1.00 120.27 ? 436 LEU B CD2 1 
ATOM   5765 N N   . SER B 2 448 ? 62.197  87.298  100.943 1.00 122.24 ? 437 SER B N   1 
ATOM   5766 C CA  . SER B 2 448 ? 61.649  85.957  100.797 1.00 122.24 ? 437 SER B CA  1 
ATOM   5767 C C   . SER B 2 448 ? 62.801  84.972  100.658 1.00 122.24 ? 437 SER B C   1 
ATOM   5768 O O   . SER B 2 448 ? 63.975  85.348  100.689 1.00 122.24 ? 437 SER B O   1 
ATOM   5769 C CB  . SER B 2 448 ? 60.699  85.863  99.602  1.00 122.24 ? 437 SER B CB  1 
ATOM   5770 O OG  . SER B 2 448 ? 60.022  84.619  99.599  1.00 122.24 ? 437 SER B OG  1 
ATOM   5771 N N   . GLN B 2 449 ? 62.446  83.696  100.494 1.00 127.89 ? 438 GLN B N   1 
ATOM   5772 C CA  . GLN B 2 449 ? 63.457  82.648  100.427 1.00 127.89 ? 438 GLN B CA  1 
ATOM   5773 C C   . GLN B 2 449 ? 64.259  82.726  99.135  1.00 127.89 ? 438 GLN B C   1 
ATOM   5774 O O   . GLN B 2 449 ? 65.487  82.591  99.152  1.00 127.89 ? 438 GLN B O   1 
ATOM   5775 C CB  . GLN B 2 449 ? 62.796  81.278  100.570 1.00 127.89 ? 438 GLN B CB  1 
ATOM   5776 C CG  . GLN B 2 449 ? 61.545  81.107  99.727  1.00 127.89 ? 438 GLN B CG  1 
ATOM   5777 C CD  . GLN B 2 449 ? 60.821  79.809  100.015 1.00 127.89 ? 438 GLN B CD  1 
ATOM   5778 O OE1 . GLN B 2 449 ? 61.083  79.149  101.021 1.00 127.89 ? 438 GLN B OE1 1 
ATOM   5779 N NE2 . GLN B 2 449 ? 59.904  79.434  99.131  1.00 127.89 ? 438 GLN B NE2 1 
ATOM   5780 N N   . ALA B 2 450 ? 63.586  82.934  98.004  1.00 125.78 ? 439 ALA B N   1 
ATOM   5781 C CA  . ALA B 2 450 ? 64.277  83.041  96.728  1.00 125.78 ? 439 ALA B CA  1 
ATOM   5782 C C   . ALA B 2 450 ? 63.708  84.112  95.809  1.00 125.78 ? 439 ALA B C   1 
ATOM   5783 O O   . ALA B 2 450 ? 64.189  84.243  94.679  1.00 125.78 ? 439 ALA B O   1 
ATOM   5784 C CB  . ALA B 2 450 ? 64.261  81.689  95.998  1.00 125.78 ? 439 ALA B CB  1 
ATOM   5785 N N   . ARG B 2 451 ? 62.716  84.879  96.245  1.00 124.13 ? 440 ARG B N   1 
ATOM   5786 C CA  . ARG B 2 451 ? 62.108  85.893  95.401  1.00 124.13 ? 440 ARG B CA  1 
ATOM   5787 C C   . ARG B 2 451 ? 62.967  87.151  95.367  1.00 124.13 ? 440 ARG B C   1 
ATOM   5788 O O   . ARG B 2 451 ? 63.776  87.410  96.260  1.00 124.13 ? 440 ARG B O   1 
ATOM   5789 C CB  . ARG B 2 451 ? 60.701  86.230  95.893  1.00 124.13 ? 440 ARG B CB  1 
ATOM   5790 C CG  . ARG B 2 451 ? 59.764  85.036  95.952  1.00 124.13 ? 440 ARG B CG  1 
ATOM   5791 C CD  . ARG B 2 451 ? 59.011  84.855  94.646  1.00 124.13 ? 440 ARG B CD  1 
ATOM   5792 N NE  . ARG B 2 451 ? 59.886  84.398  93.571  1.00 124.13 ? 440 ARG B NE  1 
ATOM   5793 C CZ  . ARG B 2 451 ? 60.293  83.142  93.424  1.00 124.13 ? 440 ARG B CZ  1 
ATOM   5794 N NH1 . ARG B 2 451 ? 61.092  82.815  92.417  1.00 124.13 ? 440 ARG B NH1 1 
ATOM   5795 N NH2 . ARG B 2 451 ? 59.901  82.210  94.282  1.00 124.13 ? 440 ARG B NH2 1 
ATOM   5796 N N   . LEU B 2 452 ? 62.783  87.934  94.309  1.00 120.48 ? 441 LEU B N   1 
ATOM   5797 C CA  . LEU B 2 452 ? 63.533  89.166  94.138  1.00 120.48 ? 441 LEU B CA  1 
ATOM   5798 C C   . LEU B 2 452 ? 62.909  90.290  94.963  1.00 120.48 ? 441 LEU B C   1 
ATOM   5799 O O   . LEU B 2 452 ? 61.814  90.161  95.516  1.00 120.48 ? 441 LEU B O   1 
ATOM   5800 C CB  . LEU B 2 452 ? 63.587  89.558  92.662  1.00 120.48 ? 441 LEU B CB  1 
ATOM   5801 C CG  . LEU B 2 452 ? 64.059  88.481  91.684  1.00 120.48 ? 441 LEU B CG  1 
ATOM   5802 C CD1 . LEU B 2 452 ? 62.871  87.775  91.054  1.00 120.48 ? 441 LEU B CD1 1 
ATOM   5803 C CD2 . LEU B 2 452 ? 64.952  89.077  90.613  1.00 120.48 ? 441 LEU B CD2 1 
ATOM   5804 N N   . LEU B 2 453 ? 63.627  91.411  95.042  1.00 115.16 ? 442 LEU B N   1 
ATOM   5805 C CA  . LEU B 2 453 ? 63.085  92.578  95.730  1.00 115.16 ? 442 LEU B CA  1 
ATOM   5806 C C   . LEU B 2 453 ? 61.927  93.189  94.952  1.00 115.16 ? 442 LEU B C   1 
ATOM   5807 O O   . LEU B 2 453 ? 60.875  93.491  95.527  1.00 115.16 ? 442 LEU B O   1 
ATOM   5808 C CB  . LEU B 2 453 ? 64.180  93.619  95.956  1.00 115.16 ? 442 LEU B CB  1 
ATOM   5809 C CG  . LEU B 2 453 ? 65.411  93.220  96.770  1.00 115.16 ? 442 LEU B CG  1 
ATOM   5810 C CD1 . LEU B 2 453 ? 66.450  94.323  96.721  1.00 115.16 ? 442 LEU B CD1 1 
ATOM   5811 C CD2 . LEU B 2 453 ? 65.036  92.901  98.203  1.00 115.16 ? 442 LEU B CD2 1 
ATOM   5812 N N   . THR B 2 454 ? 62.101  93.375  93.643  1.00 119.88 ? 443 THR B N   1 
ATOM   5813 C CA  . THR B 2 454 ? 61.112  94.071  92.830  1.00 119.88 ? 443 THR B CA  1 
ATOM   5814 C C   . THR B 2 454 ? 59.786  93.330  92.729  1.00 119.88 ? 443 THR B C   1 
ATOM   5815 O O   . THR B 2 454 ? 58.801  93.927  92.280  1.00 119.88 ? 443 THR B O   1 
ATOM   5816 C CB  . THR B 2 454 ? 61.664  94.313  91.426  1.00 119.88 ? 443 THR B CB  1 
ATOM   5817 O OG1 . THR B 2 454 ? 61.670  93.081  90.694  1.00 119.88 ? 443 THR B OG1 1 
ATOM   5818 C CG2 . THR B 2 454 ? 63.079  94.859  91.504  1.00 119.88 ? 443 THR B CG2 1 
ATOM   5819 N N   . SER B 2 455 ? 59.727  92.061  93.130  1.00 122.23 ? 444 SER B N   1 
ATOM   5820 C CA  . SER B 2 455 ? 58.458  91.345  93.108  1.00 122.23 ? 444 SER B CA  1 
ATOM   5821 C C   . SER B 2 455 ? 57.498  91.819  94.189  1.00 122.23 ? 444 SER B C   1 
ATOM   5822 O O   . SER B 2 455 ? 56.348  91.370  94.212  1.00 122.23 ? 444 SER B O   1 
ATOM   5823 C CB  . SER B 2 455 ? 58.700  89.843  93.252  1.00 122.23 ? 444 SER B CB  1 
ATOM   5824 O OG  . SER B 2 455 ? 59.419  89.337  92.142  1.00 122.23 ? 444 SER B OG  1 
ATOM   5825 N N   . PHE B 2 456 ? 57.938  92.710  95.077  1.00 124.04 ? 445 PHE B N   1 
ATOM   5826 C CA  . PHE B 2 456 ? 57.075  93.254  96.117  1.00 124.04 ? 445 PHE B CA  1 
ATOM   5827 C C   . PHE B 2 456 ? 57.214  94.755  96.301  1.00 124.04 ? 445 PHE B C   1 
ATOM   5828 O O   . PHE B 2 456 ? 56.535  95.307  97.173  1.00 124.04 ? 445 PHE B O   1 
ATOM   5829 C CB  . PHE B 2 456 ? 57.355  92.571  97.465  1.00 124.04 ? 445 PHE B CB  1 
ATOM   5830 C CG  . PHE B 2 456 ? 57.635  91.099  97.358  1.00 124.04 ? 445 PHE B CG  1 
ATOM   5831 C CD1 . PHE B 2 456 ? 56.602  90.179  97.402  1.00 124.04 ? 445 PHE B CD1 1 
ATOM   5832 C CD2 . PHE B 2 456 ? 58.933  90.635  97.225  1.00 124.04 ? 445 PHE B CD2 1 
ATOM   5833 C CE1 . PHE B 2 456 ? 56.858  88.827  97.307  1.00 124.04 ? 445 PHE B CE1 1 
ATOM   5834 C CE2 . PHE B 2 456 ? 59.194  89.284  97.129  1.00 124.04 ? 445 PHE B CE2 1 
ATOM   5835 C CZ  . PHE B 2 456 ? 58.155  88.379  97.170  1.00 124.04 ? 445 PHE B CZ  1 
ATOM   5836 N N   . LEU B 2 457 ? 58.058  95.435  95.528  1.00 124.53 ? 446 LEU B N   1 
ATOM   5837 C CA  . LEU B 2 457 ? 58.366  96.832  95.773  1.00 124.53 ? 446 LEU B CA  1 
ATOM   5838 C C   . LEU B 2 457 ? 58.269  97.636  94.485  1.00 124.53 ? 446 LEU B C   1 
ATOM   5839 O O   . LEU B 2 457 ? 58.684  97.161  93.421  1.00 124.53 ? 446 LEU B O   1 
ATOM   5840 C CB  . LEU B 2 457 ? 59.778  96.972  96.352  1.00 124.53 ? 446 LEU B CB  1 
ATOM   5841 C CG  . LEU B 2 457 ? 60.025  96.246  97.672  1.00 124.53 ? 446 LEU B CG  1 
ATOM   5842 C CD1 . LEU B 2 457 ? 61.482  96.377  98.081  1.00 124.53 ? 446 LEU B CD1 1 
ATOM   5843 C CD2 . LEU B 2 457 ? 59.095  96.760  98.758  1.00 124.53 ? 446 LEU B CD2 1 
ATOM   5844 N N   . PRO B 2 458 ? 57.730  98.850  94.545  1.00 124.66 ? 447 PRO B N   1 
ATOM   5845 C CA  . PRO B 2 458 ? 57.801  99.745  93.387  1.00 124.66 ? 447 PRO B CA  1 
ATOM   5846 C C   . PRO B 2 458 ? 59.238  100.145 93.092  1.00 124.66 ? 447 PRO B C   1 
ATOM   5847 O O   . PRO B 2 458 ? 60.122  100.086 93.950  1.00 124.66 ? 447 PRO B O   1 
ATOM   5848 C CB  . PRO B 2 458 ? 56.961  100.954 93.813  1.00 124.66 ? 447 PRO B CB  1 
ATOM   5849 C CG  . PRO B 2 458 ? 56.910  100.884 95.303  1.00 124.66 ? 447 PRO B CG  1 
ATOM   5850 C CD  . PRO B 2 458 ? 56.943  99.428  95.645  1.00 124.66 ? 447 PRO B CD  1 
ATOM   5851 N N   . ALA B 2 459 ? 59.463  100.561 91.844  1.00 126.58 ? 448 ALA B N   1 
ATOM   5852 C CA  . ALA B 2 459 ? 60.815  100.870 91.392  1.00 126.58 ? 448 ALA B CA  1 
ATOM   5853 C C   . ALA B 2 459 ? 61.398  102.103 92.069  1.00 126.58 ? 448 ALA B C   1 
ATOM   5854 O O   . ALA B 2 459 ? 62.623  102.204 92.192  1.00 126.58 ? 448 ALA B O   1 
ATOM   5855 C CB  . ALA B 2 459 ? 60.831  101.058 89.875  1.00 126.58 ? 448 ALA B CB  1 
ATOM   5856 N N   . GLN B 2 460 ? 60.560  103.041 92.505  1.00 128.54 ? 449 GLN B N   1 
ATOM   5857 C CA  . GLN B 2 460 ? 61.036  104.210 93.229  1.00 128.54 ? 449 GLN B CA  1 
ATOM   5858 C C   . GLN B 2 460 ? 61.387  103.901 94.677  1.00 128.54 ? 449 GLN B C   1 
ATOM   5859 O O   . GLN B 2 460 ? 61.984  104.748 95.350  1.00 128.54 ? 449 GLN B O   1 
ATOM   5860 C CB  . GLN B 2 460 ? 59.985  105.324 93.186  1.00 128.54 ? 449 GLN B CB  1 
ATOM   5861 C CG  . GLN B 2 460 ? 58.763  105.054 94.044  1.00 128.54 ? 449 GLN B CG  1 
ATOM   5862 C CD  . GLN B 2 460 ? 57.600  104.513 93.241  1.00 128.54 ? 449 GLN B CD  1 
ATOM   5863 O OE1 . GLN B 2 460 ? 57.750  104.157 92.073  1.00 128.54 ? 449 GLN B OE1 1 
ATOM   5864 N NE2 . GLN B 2 460 ? 56.430  104.447 93.865  1.00 128.54 ? 449 GLN B NE2 1 
ATOM   5865 N N   . LEU B 2 461 ? 61.032  102.714 95.164  1.00 124.76 ? 450 LEU B N   1 
ATOM   5866 C CA  . LEU B 2 461 ? 61.280  102.310 96.538  1.00 124.76 ? 450 LEU B CA  1 
ATOM   5867 C C   . LEU B 2 461 ? 62.531  101.453 96.688  1.00 124.76 ? 450 LEU B C   1 
ATOM   5868 O O   . LEU B 2 461 ? 62.972  101.219 97.817  1.00 124.76 ? 450 LEU B O   1 
ATOM   5869 C CB  . LEU B 2 461 ? 60.055  101.545 97.071  1.00 124.76 ? 450 LEU B CB  1 
ATOM   5870 C CG  . LEU B 2 461 ? 59.989  100.910 98.462  1.00 124.76 ? 450 LEU B CG  1 
ATOM   5871 C CD1 . LEU B 2 461 ? 60.448  101.881 99.529  1.00 124.76 ? 450 LEU B CD1 1 
ATOM   5872 C CD2 . LEU B 2 461 ? 58.585  100.416 98.756  1.00 124.76 ? 450 LEU B CD2 1 
ATOM   5873 N N   . LEU B 2 462 ? 63.134  101.015 95.581  1.00 117.56 ? 451 LEU B N   1 
ATOM   5874 C CA  . LEU B 2 462 ? 64.170  99.990  95.656  1.00 117.56 ? 451 LEU B CA  1 
ATOM   5875 C C   . LEU B 2 462 ? 65.450  100.518 96.291  1.00 117.56 ? 451 LEU B C   1 
ATOM   5876 O O   . LEU B 2 462 ? 66.060  99.836  97.124  1.00 117.56 ? 451 LEU B O   1 
ATOM   5877 C CB  . LEU B 2 462 ? 64.454  99.439  94.263  1.00 117.56 ? 451 LEU B CB  1 
ATOM   5878 C CG  . LEU B 2 462 ? 65.126  98.072  94.271  1.00 117.56 ? 451 LEU B CG  1 
ATOM   5879 C CD1 . LEU B 2 462 ? 64.359  97.133  95.179  1.00 117.56 ? 451 LEU B CD1 1 
ATOM   5880 C CD2 . LEU B 2 462 ? 65.187  97.520  92.868  1.00 117.56 ? 451 LEU B CD2 1 
ATOM   5881 N N   . ARG B 2 463 ? 65.892  101.711 95.890  1.00 119.14 ? 452 ARG B N   1 
ATOM   5882 C CA  . ARG B 2 463 ? 67.070  102.310 96.510  1.00 119.14 ? 452 ARG B CA  1 
ATOM   5883 C C   . ARG B 2 463 ? 66.879  102.436 98.015  1.00 119.14 ? 452 ARG B C   1 
ATOM   5884 O O   . ARG B 2 463 ? 67.801  102.178 98.801  1.00 119.14 ? 452 ARG B O   1 
ATOM   5885 C CB  . ARG B 2 463 ? 67.344  103.679 95.888  1.00 119.14 ? 452 ARG B CB  1 
ATOM   5886 C CG  . ARG B 2 463 ? 67.975  103.638 94.506  1.00 119.14 ? 452 ARG B CG  1 
ATOM   5887 C CD  . ARG B 2 463 ? 67.869  104.994 93.828  1.00 119.14 ? 452 ARG B CD  1 
ATOM   5888 N NE  . ARG B 2 463 ? 68.918  105.209 92.837  1.00 119.14 ? 452 ARG B NE  1 
ATOM   5889 C CZ  . ARG B 2 463 ? 70.082  105.792 93.102  1.00 119.14 ? 452 ARG B CZ  1 
ATOM   5890 N NH1 . ARG B 2 463 ? 70.352  106.211 94.329  1.00 119.14 ? 452 ARG B NH1 1 
ATOM   5891 N NH2 . ARG B 2 463 ? 70.980  105.954 92.144  1.00 119.14 ? 452 ARG B NH2 1 
ATOM   5892 N N   . LEU B 2 464 ? 65.667  102.806 98.430  1.00 121.76 ? 453 LEU B N   1 
ATOM   5893 C CA  . LEU B 2 464 ? 65.349  102.940 99.845  1.00 121.76 ? 453 LEU B CA  1 
ATOM   5894 C C   . LEU B 2 464 ? 65.615  101.638 100.591 1.00 121.76 ? 453 LEU B C   1 
ATOM   5895 O O   . LEU B 2 464 ? 66.376  101.605 101.564 1.00 121.76 ? 453 LEU B O   1 
ATOM   5896 C CB  . LEU B 2 464 ? 63.889  103.368 99.999  1.00 121.76 ? 453 LEU B CB  1 
ATOM   5897 C CG  . LEU B 2 464 ? 63.434  103.713 101.411 1.00 121.76 ? 453 LEU B CG  1 
ATOM   5898 C CD1 . LEU B 2 464 ? 64.478  104.589 102.048 1.00 121.76 ? 453 LEU B CD1 1 
ATOM   5899 C CD2 . LEU B 2 464 ? 62.097  104.419 101.385 1.00 121.76 ? 453 LEU B CD2 1 
ATOM   5900 N N   . TYR B 2 465 ? 64.984  100.549 100.142 1.00 114.35 ? 454 TYR B N   1 
ATOM   5901 C CA  . TYR B 2 465 ? 65.193  99.252  100.778 1.00 114.35 ? 454 TYR B CA  1 
ATOM   5902 C C   . TYR B 2 465 ? 66.657  98.844  100.753 1.00 114.35 ? 454 TYR B C   1 
ATOM   5903 O O   . TYR B 2 465 ? 67.237  98.543  101.803 1.00 114.35 ? 454 TYR B O   1 
ATOM   5904 C CB  . TYR B 2 465 ? 64.329  98.191  100.105 1.00 114.35 ? 454 TYR B CB  1 
ATOM   5905 C CG  . TYR B 2 465 ? 63.026  97.943  100.819 1.00 114.35 ? 454 TYR B CG  1 
ATOM   5906 C CD1 . TYR B 2 465 ? 61.944  98.789  100.644 1.00 114.35 ? 454 TYR B CD1 1 
ATOM   5907 C CD2 . TYR B 2 465 ? 62.884  96.870  101.685 1.00 114.35 ? 454 TYR B CD2 1 
ATOM   5908 C CE1 . TYR B 2 465 ? 60.751  98.567  101.300 1.00 114.35 ? 454 TYR B CE1 1 
ATOM   5909 C CE2 . TYR B 2 465 ? 61.696  96.638  102.343 1.00 114.35 ? 454 TYR B CE2 1 
ATOM   5910 C CZ  . TYR B 2 465 ? 60.633  97.489  102.149 1.00 114.35 ? 454 TYR B CZ  1 
ATOM   5911 O OH  . TYR B 2 465 ? 59.447  97.261  102.806 1.00 114.35 ? 454 TYR B OH  1 
ATOM   5912 N N   . GLN B 2 466 ? 67.279  98.832  99.572  1.00 107.56 ? 455 GLN B N   1 
ATOM   5913 C CA  . GLN B 2 466 ? 68.670  98.398  99.497  1.00 107.56 ? 455 GLN B CA  1 
ATOM   5914 C C   . GLN B 2 466 ? 69.608  99.256  100.329 1.00 107.56 ? 455 GLN B C   1 
ATOM   5915 O O   . GLN B 2 466 ? 70.737  98.829  100.584 1.00 107.56 ? 455 GLN B O   1 
ATOM   5916 C CB  . GLN B 2 466 ? 69.157  98.384  98.048  1.00 107.56 ? 455 GLN B CB  1 
ATOM   5917 C CG  . GLN B 2 466 ? 68.527  97.303  97.205  1.00 107.56 ? 455 GLN B CG  1 
ATOM   5918 C CD  . GLN B 2 466 ? 69.284  97.071  95.921  1.00 107.56 ? 455 GLN B CD  1 
ATOM   5919 O OE1 . GLN B 2 466 ? 70.353  97.640  95.708  1.00 107.56 ? 455 GLN B OE1 1 
ATOM   5920 N NE2 . GLN B 2 466 ? 68.733  96.233  95.053  1.00 107.56 ? 455 GLN B NE2 1 
ATOM   5921 N N   . LEU B 2 467 ? 69.181  100.440 100.762 1.00 107.55 ? 456 LEU B N   1 
ATOM   5922 C CA  . LEU B 2 467 ? 69.958  101.153 101.765 1.00 107.55 ? 456 LEU B CA  1 
ATOM   5923 C C   . LEU B 2 467 ? 69.751  100.591 103.162 1.00 107.55 ? 456 LEU B C   1 
ATOM   5924 O O   . LEU B 2 467 ? 70.670  100.645 103.986 1.00 107.55 ? 456 LEU B O   1 
ATOM   5925 C CB  . LEU B 2 467 ? 69.613  102.642 101.756 1.00 107.55 ? 456 LEU B CB  1 
ATOM   5926 C CG  . LEU B 2 467 ? 70.500  103.487 102.670 1.00 107.55 ? 456 LEU B CG  1 
ATOM   5927 C CD1 . LEU B 2 467 ? 71.958  103.247 102.350 1.00 107.55 ? 456 LEU B CD1 1 
ATOM   5928 C CD2 . LEU B 2 467 ? 70.168  104.955 102.538 1.00 107.55 ? 456 LEU B CD2 1 
ATOM   5929 N N   . MET B 2 468 ? 68.571  100.039 103.446 1.00 104.46 ? 457 MET B N   1 
ATOM   5930 C CA  . MET B 2 468 ? 68.302  99.485  104.770 1.00 104.46 ? 457 MET B CA  1 
ATOM   5931 C C   . MET B 2 468 ? 68.908  98.095  104.922 1.00 104.46 ? 457 MET B C   1 
ATOM   5932 O O   . MET B 2 468 ? 69.512  97.778  105.952 1.00 104.46 ? 457 MET B O   1 
ATOM   5933 C CB  . MET B 2 468 ? 66.794  99.434  105.021 1.00 104.46 ? 457 MET B CB  1 
ATOM   5934 C CG  . MET B 2 468 ? 66.415  98.939  106.402 1.00 104.46 ? 457 MET B CG  1 
ATOM   5935 S SD  . MET B 2 468 ? 64.632  98.886  106.653 1.00 104.46 ? 457 MET B SD  1 
ATOM   5936 C CE  . MET B 2 468 ? 64.196  97.456  105.671 1.00 104.46 ? 457 MET B CE  1 
ATOM   5937 N N   . LEU B 2 469 ? 68.745  97.251  103.901 1.00 94.21  ? 458 LEU B N   1 
ATOM   5938 C CA  . LEU B 2 469 ? 69.206  95.870  103.992 1.00 94.21  ? 458 LEU B CA  1 
ATOM   5939 C C   . LEU B 2 469 ? 70.712  95.785  104.178 1.00 94.21  ? 458 LEU B C   1 
ATOM   5940 O O   . LEU B 2 469 ? 71.201  94.861  104.835 1.00 94.21  ? 458 LEU B O   1 
ATOM   5941 C CB  . LEU B 2 469 ? 68.781  95.089  102.752 1.00 94.21  ? 458 LEU B CB  1 
ATOM   5942 C CG  . LEU B 2 469 ? 67.285  94.809  102.627 1.00 94.21  ? 458 LEU B CG  1 
ATOM   5943 C CD1 . LEU B 2 469 ? 67.038  93.621  101.715 1.00 94.21  ? 458 LEU B CD1 1 
ATOM   5944 C CD2 . LEU B 2 469 ? 66.663  94.576  103.990 1.00 94.21  ? 458 LEU B CD2 1 
ATOM   5945 N N   . PHE B 2 470 ? 71.463  96.727  103.619 1.00 94.42  ? 459 PHE B N   1 
ATOM   5946 C CA  . PHE B 2 470 ? 72.908  96.740  103.785 1.00 94.42  ? 459 PHE B CA  1 
ATOM   5947 C C   . PHE B 2 470 ? 73.355  97.464  105.043 1.00 94.42  ? 459 PHE B C   1 
ATOM   5948 O O   . PHE B 2 470 ? 74.540  97.786  105.166 1.00 94.42  ? 459 PHE B O   1 
ATOM   5949 C CB  . PHE B 2 470 ? 73.583  97.378  102.574 1.00 94.42  ? 459 PHE B CB  1 
ATOM   5950 C CG  . PHE B 2 470 ? 74.036  96.392  101.551 1.00 94.42  ? 459 PHE B CG  1 
ATOM   5951 C CD1 . PHE B 2 470 ? 75.143  95.603  101.782 1.00 94.42  ? 459 PHE B CD1 1 
ATOM   5952 C CD2 . PHE B 2 470 ? 73.373  96.269  100.351 1.00 94.42  ? 459 PHE B CD2 1 
ATOM   5953 C CE1 . PHE B 2 470 ? 75.566  94.695  100.843 1.00 94.42  ? 459 PHE B CE1 1 
ATOM   5954 C CE2 . PHE B 2 470 ? 73.799  95.369  99.405  1.00 94.42  ? 459 PHE B CE2 1 
ATOM   5955 C CZ  . PHE B 2 470 ? 74.894  94.577  99.653  1.00 94.42  ? 459 PHE B CZ  1 
ATOM   5956 N N   . THR B 2 471 ? 72.447  97.738  105.972 1.00 97.14  ? 460 THR B N   1 
ATOM   5957 C CA  . THR B 2 471 ? 72.844  98.352  107.228 1.00 97.14  ? 460 THR B CA  1 
ATOM   5958 C C   . THR B 2 471 ? 72.155  97.755  108.445 1.00 97.14  ? 460 THR B C   1 
ATOM   5959 O O   . THR B 2 471 ? 72.487  98.150  109.566 1.00 97.14  ? 460 THR B O   1 
ATOM   5960 C CB  . THR B 2 471 ? 72.582  99.865  107.194 1.00 97.14  ? 460 THR B CB  1 
ATOM   5961 O OG1 . THR B 2 471 ? 71.307  100.116 106.593 1.00 97.14  ? 460 THR B OG1 1 
ATOM   5962 C CG2 . THR B 2 471 ? 73.663  100.578 106.402 1.00 97.14  ? 460 THR B CG2 1 
ATOM   5963 N N   . LEU B 2 472 ? 71.230  96.828  108.275 1.00 93.86  ? 461 LEU B N   1 
ATOM   5964 C CA  . LEU B 2 472 ? 70.610  96.236  109.445 1.00 93.86  ? 461 LEU B CA  1 
ATOM   5965 C C   . LEU B 2 472 ? 71.552  95.222  110.091 1.00 93.86  ? 461 LEU B C   1 
ATOM   5966 O O   . LEU B 2 472 ? 72.363  94.595  109.406 1.00 93.86  ? 461 LEU B O   1 
ATOM   5967 C CB  . LEU B 2 472 ? 69.299  95.561  109.070 1.00 93.86  ? 461 LEU B CB  1 
ATOM   5968 C CG  . LEU B 2 472 ? 68.113  96.498  108.876 1.00 93.86  ? 461 LEU B CG  1 
ATOM   5969 C CD1 . LEU B 2 472 ? 66.849  95.707  108.618 1.00 93.86  ? 461 LEU B CD1 1 
ATOM   5970 C CD2 . LEU B 2 472 ? 67.950  97.371  110.096 1.00 93.86  ? 461 LEU B CD2 1 
ATOM   5971 N N   . PRO B 2 473 ? 71.469  95.047  111.411 1.00 97.72  ? 462 PRO B N   1 
ATOM   5972 C CA  . PRO B 2 473 ? 72.403  94.142  112.089 1.00 97.72  ? 462 PRO B CA  1 
ATOM   5973 C C   . PRO B 2 473 ? 72.118  92.688  111.769 1.00 97.72  ? 462 PRO B C   1 
ATOM   5974 O O   . PRO B 2 473 ? 71.491  91.974  112.556 1.00 97.72  ? 462 PRO B O   1 
ATOM   5975 C CB  . PRO B 2 473 ? 72.163  94.444  113.570 1.00 97.72  ? 462 PRO B CB  1 
ATOM   5976 C CG  . PRO B 2 473 ? 70.745  94.876  113.610 1.00 97.72  ? 462 PRO B CG  1 
ATOM   5977 C CD  . PRO B 2 473 ? 70.564  95.702  112.368 1.00 97.72  ? 462 PRO B CD  1 
ATOM   5978 N N   . GLY B 2 474 ? 72.563  92.253  110.603 1.00 94.65  ? 463 GLY B N   1 
ATOM   5979 C CA  . GLY B 2 474 ? 72.411  90.870  110.228 1.00 94.65  ? 463 GLY B CA  1 
ATOM   5980 C C   . GLY B 2 474 ? 73.164  90.579  108.956 1.00 94.65  ? 463 GLY B C   1 
ATOM   5981 O O   . GLY B 2 474 ? 74.076  91.312  108.574 1.00 94.65  ? 463 GLY B O   1 
ATOM   5982 N N   . THR B 2 475 ? 72.770  89.493  108.304 1.00 90.16  ? 464 THR B N   1 
ATOM   5983 C CA  . THR B 2 475 ? 73.294  89.166  106.990 1.00 90.16  ? 464 THR B CA  1 
ATOM   5984 C C   . THR B 2 475 ? 72.232  89.466  105.944 1.00 90.16  ? 464 THR B C   1 
ATOM   5985 O O   . THR B 2 475 ? 71.114  88.939  106.034 1.00 90.16  ? 464 THR B O   1 
ATOM   5986 C CB  . THR B 2 475 ? 73.731  87.703  106.922 1.00 90.16  ? 464 THR B CB  1 
ATOM   5987 O OG1 . THR B 2 475 ? 74.072  87.362  105.575 1.00 90.16  ? 464 THR B OG1 1 
ATOM   5988 C CG2 . THR B 2 475 ? 72.642  86.777  107.429 1.00 90.16  ? 464 THR B CG2 1 
ATOM   5989 N N   . PRO B 2 476 ? 72.500  90.337  104.973 1.00 85.44  ? 465 PRO B N   1 
ATOM   5990 C CA  . PRO B 2 476 ? 71.494  90.626  103.946 1.00 85.44  ? 465 PRO B CA  1 
ATOM   5991 C C   . PRO B 2 476 ? 71.572  89.642  102.791 1.00 85.44  ? 465 PRO B C   1 
ATOM   5992 O O   . PRO B 2 476 ? 72.648  89.276  102.318 1.00 85.44  ? 465 PRO B O   1 
ATOM   5993 C CB  . PRO B 2 476 ? 71.871  92.040  103.493 1.00 85.44  ? 465 PRO B CB  1 
ATOM   5994 C CG  . PRO B 2 476 ? 73.333  92.109  103.711 1.00 85.44  ? 465 PRO B CG  1 
ATOM   5995 C CD  . PRO B 2 476 ? 73.641  91.264  104.910 1.00 85.44  ? 465 PRO B CD  1 
ATOM   5996 N N   . VAL B 2 477 ? 70.403  89.210  102.331 1.00 88.48  ? 466 VAL B N   1 
ATOM   5997 C CA  . VAL B 2 477 ? 70.291  88.085  101.412 1.00 88.48  ? 466 VAL B CA  1 
ATOM   5998 C C   . VAL B 2 477 ? 69.492  88.530  100.194 1.00 88.48  ? 466 VAL B C   1 
ATOM   5999 O O   . VAL B 2 477 ? 68.261  88.643  100.258 1.00 88.48  ? 466 VAL B O   1 
ATOM   6000 C CB  . VAL B 2 477 ? 69.642  86.875  102.091 1.00 88.48  ? 466 VAL B CB  1 
ATOM   6001 C CG1 . VAL B 2 477 ? 69.502  85.743  101.124 1.00 88.48  ? 466 VAL B CG1 1 
ATOM   6002 C CG2 . VAL B 2 477 ? 70.471  86.440  103.279 1.00 88.48  ? 466 VAL B CG2 1 
ATOM   6003 N N   . PHE B 2 478 ? 70.184  88.768  99.081  1.00 90.24  ? 467 PHE B N   1 
ATOM   6004 C CA  . PHE B 2 478 ? 69.571  89.191  97.829  1.00 90.24  ? 467 PHE B CA  1 
ATOM   6005 C C   . PHE B 2 478 ? 69.561  88.051  96.821  1.00 90.24  ? 467 PHE B C   1 
ATOM   6006 O O   . PHE B 2 478 ? 70.460  87.206  96.801  1.00 90.24  ? 467 PHE B O   1 
ATOM   6007 C CB  . PHE B 2 478 ? 70.317  90.377  97.221  1.00 90.24  ? 467 PHE B CB  1 
ATOM   6008 C CG  . PHE B 2 478 ? 70.503  91.516  98.163  1.00 90.24  ? 467 PHE B CG  1 
ATOM   6009 C CD1 . PHE B 2 478 ? 69.452  92.364  98.456  1.00 90.24  ? 467 PHE B CD1 1 
ATOM   6010 C CD2 . PHE B 2 478 ? 71.721  91.732  98.768  1.00 90.24  ? 467 PHE B CD2 1 
ATOM   6011 C CE1 . PHE B 2 478 ? 69.619  93.416  99.327  1.00 90.24  ? 467 PHE B CE1 1 
ATOM   6012 C CE2 . PHE B 2 478 ? 71.891  92.776  99.642  1.00 90.24  ? 467 PHE B CE2 1 
ATOM   6013 C CZ  . PHE B 2 478 ? 70.840  93.622  99.920  1.00 90.24  ? 467 PHE B CZ  1 
ATOM   6014 N N   . SER B 2 479 ? 68.539  88.041  95.973  1.00 104.64 ? 468 SER B N   1 
ATOM   6015 C CA  . SER B 2 479 ? 68.517  87.100  94.868  1.00 104.64 ? 468 SER B CA  1 
ATOM   6016 C C   . SER B 2 479 ? 69.337  87.646  93.700  1.00 104.64 ? 468 SER B C   1 
ATOM   6017 O O   . SER B 2 479 ? 69.842  88.771  93.732  1.00 104.64 ? 468 SER B O   1 
ATOM   6018 C CB  . SER B 2 479 ? 67.082  86.815  94.436  1.00 104.64 ? 468 SER B CB  1 
ATOM   6019 O OG  . SER B 2 479 ? 67.006  85.617  93.686  1.00 104.64 ? 468 SER B OG  1 
ATOM   6020 N N   . TYR B 2 480 ? 69.474  86.833  92.657  1.00 109.67 ? 469 TYR B N   1 
ATOM   6021 C CA  . TYR B 2 480 ? 70.234  87.253  91.487  1.00 109.67 ? 469 TYR B CA  1 
ATOM   6022 C C   . TYR B 2 480 ? 69.466  88.334  90.745  1.00 109.67 ? 469 TYR B C   1 
ATOM   6023 O O   . TYR B 2 480 ? 68.281  88.168  90.441  1.00 109.67 ? 469 TYR B O   1 
ATOM   6024 C CB  . TYR B 2 480 ? 70.515  86.066  90.571  1.00 109.67 ? 469 TYR B CB  1 
ATOM   6025 C CG  . TYR B 2 480 ? 69.297  85.502  89.885  1.00 109.67 ? 469 TYR B CG  1 
ATOM   6026 C CD1 . TYR B 2 480 ? 68.471  84.597  90.531  1.00 109.67 ? 469 TYR B CD1 1 
ATOM   6027 C CD2 . TYR B 2 480 ? 68.996  85.846  88.579  1.00 109.67 ? 469 TYR B CD2 1 
ATOM   6028 C CE1 . TYR B 2 480 ? 67.362  84.074  89.905  1.00 109.67 ? 469 TYR B CE1 1 
ATOM   6029 C CE2 . TYR B 2 480 ? 67.892  85.326  87.945  1.00 109.67 ? 469 TYR B CE2 1 
ATOM   6030 C CZ  . TYR B 2 480 ? 67.077  84.440  88.610  1.00 109.67 ? 469 TYR B CZ  1 
ATOM   6031 O OH  . TYR B 2 480 ? 65.974  83.919  87.976  1.00 109.67 ? 469 TYR B OH  1 
ATOM   6032 N N   . GLY B 2 481 ? 70.127  89.455  90.481  1.00 114.90 ? 470 GLY B N   1 
ATOM   6033 C CA  . GLY B 2 481 ? 69.535  90.520  89.700  1.00 114.90 ? 470 GLY B CA  1 
ATOM   6034 C C   . GLY B 2 481 ? 69.064  91.712  90.495  1.00 114.90 ? 470 GLY B C   1 
ATOM   6035 O O   . GLY B 2 481 ? 68.686  92.723  89.892  1.00 114.90 ? 470 GLY B O   1 
ATOM   6036 N N   . ASP B 2 482 ? 69.069  91.641  91.822  1.00 107.77 ? 471 ASP B N   1 
ATOM   6037 C CA  . ASP B 2 482 ? 68.634  92.785  92.604  1.00 107.77 ? 471 ASP B CA  1 
ATOM   6038 C C   . ASP B 2 482 ? 69.776  93.734  92.918  1.00 107.77 ? 471 ASP B C   1 
ATOM   6039 O O   . ASP B 2 482 ? 69.656  94.548  93.838  1.00 107.77 ? 471 ASP B O   1 
ATOM   6040 C CB  . ASP B 2 482 ? 67.961  92.308  93.886  1.00 107.77 ? 471 ASP B CB  1 
ATOM   6041 C CG  . ASP B 2 482 ? 66.726  91.485  93.605  1.00 107.77 ? 471 ASP B CG  1 
ATOM   6042 O OD1 . ASP B 2 482 ? 66.491  91.175  92.420  1.00 107.77 ? 471 ASP B OD1 1 
ATOM   6043 O OD2 . ASP B 2 482 ? 65.990  91.150  94.554  1.00 107.77 ? 471 ASP B OD2 1 
ATOM   6044 N N   . GLU B 2 483 ? 70.880  93.642  92.178  1.00 112.81 ? 472 GLU B N   1 
ATOM   6045 C CA  . GLU B 2 483 ? 71.891  94.688  92.216  1.00 112.81 ? 472 GLU B CA  1 
ATOM   6046 C C   . GLU B 2 483 ? 71.726  95.672  91.066  1.00 112.81 ? 472 GLU B C   1 
ATOM   6047 O O   . GLU B 2 483 ? 72.491  96.637  90.973  1.00 112.81 ? 472 GLU B O   1 
ATOM   6048 C CB  . GLU B 2 483 ? 73.287  94.067  92.191  1.00 112.81 ? 472 GLU B CB  1 
ATOM   6049 C CG  . GLU B 2 483 ? 73.729  93.588  90.823  1.00 112.81 ? 472 GLU B CG  1 
ATOM   6050 C CD  . GLU B 2 483 ? 73.466  92.113  90.614  1.00 112.81 ? 472 GLU B CD  1 
ATOM   6051 O OE1 . GLU B 2 483 ? 72.415  91.623  91.079  1.00 112.81 ? 472 GLU B OE1 1 
ATOM   6052 O OE2 . GLU B 2 483 ? 74.311  91.442  89.988  1.00 112.81 ? 472 GLU B OE2 1 
ATOM   6053 N N   . ILE B 2 484 ? 70.750  95.444  90.188  1.00 117.83 ? 473 ILE B N   1 
ATOM   6054 C CA  . ILE B 2 484 ? 70.454  96.333  89.072  1.00 117.83 ? 473 ILE B CA  1 
ATOM   6055 C C   . ILE B 2 484 ? 69.027  96.839  89.103  1.00 117.83 ? 473 ILE B C   1 
ATOM   6056 O O   . ILE B 2 484 ? 68.695  97.770  88.357  1.00 117.83 ? 473 ILE B O   1 
ATOM   6057 C CB  . ILE B 2 484 ? 70.734  95.649  87.723  1.00 117.83 ? 473 ILE B CB  1 
ATOM   6058 C CG1 . ILE B 2 484 ? 69.594  94.689  87.381  1.00 117.83 ? 473 ILE B CG1 1 
ATOM   6059 C CG2 . ILE B 2 484 ? 72.058  94.915  87.758  1.00 117.83 ? 473 ILE B CG2 1 
ATOM   6060 C CD1 . ILE B 2 484 ? 69.697  94.083  86.008  1.00 117.83 ? 473 ILE B CD1 1 
ATOM   6061 N N   . GLY B 2 485 ? 68.170  96.261  89.938  1.00 118.16 ? 474 GLY B N   1 
ATOM   6062 C CA  . GLY B 2 485 ? 66.759  96.576  89.885  1.00 118.16 ? 474 GLY B CA  1 
ATOM   6063 C C   . GLY B 2 485 ? 65.990  95.761  88.875  1.00 118.16 ? 474 GLY B C   1 
ATOM   6064 O O   . GLY B 2 485 ? 64.972  96.230  88.357  1.00 118.16 ? 474 GLY B O   1 
ATOM   6065 N N   . LEU B 2 486 ? 66.460  94.554  88.571  1.00 119.90 ? 475 LEU B N   1 
ATOM   6066 C CA  . LEU B 2 486 ? 65.794  93.692  87.604  1.00 119.90 ? 475 LEU B CA  1 
ATOM   6067 C C   . LEU B 2 486 ? 64.349  93.439  88.007  1.00 119.90 ? 475 LEU B C   1 
ATOM   6068 O O   . LEU B 2 486 ? 64.076  92.954  89.109  1.00 119.90 ? 475 LEU B O   1 
ATOM   6069 C CB  . LEU B 2 486 ? 66.547  92.370  87.483  1.00 119.90 ? 475 LEU B CB  1 
ATOM   6070 C CG  . LEU B 2 486 ? 65.754  91.209  86.884  1.00 119.90 ? 475 LEU B CG  1 
ATOM   6071 C CD1 . LEU B 2 486 ? 65.427  91.477  85.424  1.00 119.90 ? 475 LEU B CD1 1 
ATOM   6072 C CD2 . LEU B 2 486 ? 66.513  89.902  87.042  1.00 119.90 ? 475 LEU B CD2 1 
ATOM   6073 N N   . ASP B 2 487 ? 63.427  93.764  87.110  1.00 127.95 ? 476 ASP B N   1 
ATOM   6074 C CA  . ASP B 2 487 ? 62.009  93.512  87.312  1.00 127.95 ? 476 ASP B CA  1 
ATOM   6075 C C   . ASP B 2 487 ? 61.595  92.286  86.513  1.00 127.95 ? 476 ASP B C   1 
ATOM   6076 O O   . ASP B 2 487 ? 62.131  92.026  85.432  1.00 127.95 ? 476 ASP B O   1 
ATOM   6077 C CB  . ASP B 2 487 ? 61.175  94.725  86.889  1.00 127.95 ? 476 ASP B CB  1 
ATOM   6078 C CG  . ASP B 2 487 ? 59.680  94.492  87.032  1.00 127.95 ? 476 ASP B CG  1 
ATOM   6079 O OD1 . ASP B 2 487 ? 59.280  93.547  87.746  1.00 127.95 ? 476 ASP B OD1 1 
ATOM   6080 O OD2 . ASP B 2 487 ? 58.901  95.257  86.427  1.00 127.95 ? 476 ASP B OD2 1 
ATOM   6081 N N   . ALA B 2 488 ? 60.639  91.535  87.050  1.00 130.96 ? 477 ALA B N   1 
ATOM   6082 C CA  . ALA B 2 488 ? 60.111  90.364  86.368  1.00 130.96 ? 477 ALA B CA  1 
ATOM   6083 C C   . ALA B 2 488 ? 58.879  90.671  85.530  1.00 130.96 ? 477 ALA B C   1 
ATOM   6084 O O   . ALA B 2 488 ? 58.420  89.795  84.789  1.00 130.96 ? 477 ALA B O   1 
ATOM   6085 C CB  . ALA B 2 488 ? 59.778  89.266  87.383  1.00 130.96 ? 477 ALA B CB  1 
ATOM   6086 N N   . ALA B 2 489 ? 58.339  91.887  85.620  1.00 134.95 ? 478 ALA B N   1 
ATOM   6087 C CA  . ALA B 2 489 ? 57.151  92.266  84.873  1.00 134.95 ? 478 ALA B CA  1 
ATOM   6088 C C   . ALA B 2 489 ? 57.404  93.353  83.839  1.00 134.95 ? 478 ALA B C   1 
ATOM   6089 O O   . ALA B 2 489 ? 56.574  93.532  82.942  1.00 134.95 ? 478 ALA B O   1 
ATOM   6090 C CB  . ALA B 2 489 ? 56.045  92.733  85.831  1.00 134.95 ? 478 ALA B CB  1 
ATOM   6091 N N   . ALA B 2 490 ? 58.516  94.083  83.941  1.00 138.55 ? 479 ALA B N   1 
ATOM   6092 C CA  . ALA B 2 490 ? 58.840  95.095  82.940  1.00 138.55 ? 479 ALA B CA  1 
ATOM   6093 C C   . ALA B 2 490 ? 59.120  94.454  81.586  1.00 138.55 ? 479 ALA B C   1 
ATOM   6094 O O   . ALA B 2 490 ? 58.609  94.904  80.554  1.00 138.55 ? 479 ALA B O   1 
ATOM   6095 C CB  . ALA B 2 490 ? 60.038  95.928  83.402  1.00 138.55 ? 479 ALA B CB  1 
ATOM   6096 N N   . LEU B 2 491 ? 59.932  93.405  81.572  1.00 140.78 ? 480 LEU B N   1 
ATOM   6097 C CA  . LEU B 2 491 ? 60.210  92.698  80.332  1.00 140.78 ? 480 LEU B CA  1 
ATOM   6098 C C   . LEU B 2 491 ? 59.051  91.756  80.015  1.00 140.78 ? 480 LEU B C   1 
ATOM   6099 O O   . LEU B 2 491 ? 58.739  90.871  80.824  1.00 140.78 ? 480 LEU B O   1 
ATOM   6100 C CB  . LEU B 2 491 ? 61.527  91.929  80.447  1.00 140.78 ? 480 LEU B CB  1 
ATOM   6101 C CG  . LEU B 2 491 ? 62.063  91.178  79.227  1.00 140.78 ? 480 LEU B CG  1 
ATOM   6102 C CD1 . LEU B 2 491 ? 63.579  91.188  79.239  1.00 140.78 ? 480 LEU B CD1 1 
ATOM   6103 C CD2 . LEU B 2 491 ? 61.564  89.751  79.221  1.00 140.78 ? 480 LEU B CD2 1 
ATOM   6104 N N   . PRO B 2 492 ? 58.389  91.915  78.871  1.00 147.00 ? 481 PRO B N   1 
ATOM   6105 C CA  . PRO B 2 492 ? 57.224  91.073  78.570  1.00 147.00 ? 481 PRO B CA  1 
ATOM   6106 C C   . PRO B 2 492 ? 57.621  89.624  78.325  1.00 147.00 ? 481 PRO B C   1 
ATOM   6107 O O   . PRO B 2 492 ? 58.715  89.332  77.838  1.00 147.00 ? 481 PRO B O   1 
ATOM   6108 C CB  . PRO B 2 492 ? 56.638  91.714  77.305  1.00 147.00 ? 481 PRO B CB  1 
ATOM   6109 C CG  . PRO B 2 492 ? 57.233  93.091  77.247  1.00 147.00 ? 481 PRO B CG  1 
ATOM   6110 C CD  . PRO B 2 492 ? 58.590  92.964  77.859  1.00 147.00 ? 481 PRO B CD  1 
ATOM   6111 N N   . GLY B 2 493 ? 56.710  88.717  78.662  1.00 143.27 ? 482 GLY B N   1 
ATOM   6112 C CA  . GLY B 2 493 ? 56.934  87.298  78.425  1.00 143.27 ? 482 GLY B CA  1 
ATOM   6113 C C   . GLY B 2 493 ? 58.035  86.692  79.268  1.00 143.27 ? 482 GLY B C   1 
ATOM   6114 O O   . GLY B 2 493 ? 58.680  85.726  78.843  1.00 143.27 ? 482 GLY B O   1 
ATOM   6115 N N   . GLN B 2 494 ? 58.263  87.237  80.461  1.00 138.37 ? 483 GLN B N   1 
ATOM   6116 C CA  . GLN B 2 494 ? 59.308  86.745  81.349  1.00 138.37 ? 483 GLN B CA  1 
ATOM   6117 C C   . GLN B 2 494 ? 58.696  85.915  82.464  1.00 138.37 ? 483 GLN B C   1 
ATOM   6118 O O   . GLN B 2 494 ? 57.714  86.351  83.082  1.00 138.37 ? 483 GLN B O   1 
ATOM   6119 C CB  . GLN B 2 494 ? 60.090  87.912  81.947  1.00 138.37 ? 483 GLN B CB  1 
ATOM   6120 C CG  . GLN B 2 494 ? 61.445  87.548  82.546  1.00 138.37 ? 483 GLN B CG  1 
ATOM   6121 C CD  . GLN B 2 494 ? 62.284  86.663  81.644  1.00 138.37 ? 483 GLN B CD  1 
ATOM   6122 O OE1 . GLN B 2 494 ? 62.324  86.851  80.429  1.00 138.37 ? 483 GLN B OE1 1 
ATOM   6123 N NE2 . GLN B 2 494 ? 62.971  85.698  82.240  1.00 138.37 ? 483 GLN B NE2 1 
ATOM   6124 N N   . PRO B 2 495 ? 59.224  84.724  82.746  1.00 138.21 ? 484 PRO B N   1 
ATOM   6125 C CA  . PRO B 2 495 ? 58.736  83.965  83.901  1.00 138.21 ? 484 PRO B CA  1 
ATOM   6126 C C   . PRO B 2 495 ? 59.059  84.682  85.202  1.00 138.21 ? 484 PRO B C   1 
ATOM   6127 O O   . PRO B 2 495 ? 60.212  85.015  85.488  1.00 138.21 ? 484 PRO B O   1 
ATOM   6128 C CB  . PRO B 2 495 ? 59.482  82.629  83.793  1.00 138.21 ? 484 PRO B CB  1 
ATOM   6129 C CG  . PRO B 2 495 ? 60.678  82.927  82.951  1.00 138.21 ? 484 PRO B CG  1 
ATOM   6130 C CD  . PRO B 2 495 ? 60.233  83.976  81.979  1.00 138.21 ? 484 PRO B CD  1 
ATOM   6131 N N   . MET B 2 496 ? 58.014  84.917  85.996  1.00 139.55 ? 485 MET B N   1 
ATOM   6132 C CA  . MET B 2 496 ? 58.116  85.677  87.238  1.00 139.55 ? 485 MET B CA  1 
ATOM   6133 C C   . MET B 2 496 ? 59.019  84.991  88.257  1.00 139.55 ? 485 MET B C   1 
ATOM   6134 O O   . MET B 2 496 ? 59.841  85.646  88.905  1.00 139.55 ? 485 MET B O   1 
ATOM   6135 C CB  . MET B 2 496 ? 56.717  85.892  87.833  1.00 139.55 ? 485 MET B CB  1 
ATOM   6136 C CG  . MET B 2 496 ? 55.791  86.745  86.980  1.00 139.55 ? 485 MET B CG  1 
ATOM   6137 S SD  . MET B 2 496 ? 56.346  88.451  86.825  1.00 139.55 ? 485 MET B SD  1 
ATOM   6138 C CE  . MET B 2 496 ? 55.197  89.070  85.599  1.00 139.55 ? 485 MET B CE  1 
ATOM   6139 N N   . GLU B 2 497 ? 58.876  83.673  88.411  1.00 133.53 ? 486 GLU B N   1 
ATOM   6140 C CA  . GLU B 2 497 ? 59.601  82.963  89.459  1.00 133.53 ? 486 GLU B CA  1 
ATOM   6141 C C   . GLU B 2 497 ? 61.105  82.981  89.216  1.00 133.53 ? 486 GLU B C   1 
ATOM   6142 O O   . GLU B 2 497 ? 61.893  83.010  90.168  1.00 133.53 ? 486 GLU B O   1 
ATOM   6143 C CB  . GLU B 2 497 ? 59.090  81.525  89.568  1.00 133.53 ? 486 GLU B CB  1 
ATOM   6144 C CG  . GLU B 2 497 ? 59.187  80.714  88.281  1.00 133.53 ? 486 GLU B CG  1 
ATOM   6145 C CD  . GLU B 2 497 ? 58.007  80.936  87.352  1.00 133.53 ? 486 GLU B CD  1 
ATOM   6146 O OE1 . GLU B 2 497 ? 57.263  79.967  87.092  1.00 133.53 ? 486 GLU B OE1 1 
ATOM   6147 O OE2 . GLU B 2 497 ? 57.828  82.077  86.877  1.00 133.53 ? 486 GLU B OE2 1 
ATOM   6148 N N   . ALA B 2 498 ? 61.525  82.968  87.953  1.00 131.71 ? 487 ALA B N   1 
ATOM   6149 C CA  . ALA B 2 498 ? 62.943  82.908  87.598  1.00 131.71 ? 487 ALA B CA  1 
ATOM   6150 C C   . ALA B 2 498 ? 63.202  83.782  86.381  1.00 131.71 ? 487 ALA B C   1 
ATOM   6151 O O   . ALA B 2 498 ? 63.294  83.292  85.249  1.00 131.71 ? 487 ALA B O   1 
ATOM   6152 C CB  . ALA B 2 498 ? 63.385  81.466  87.339  1.00 131.71 ? 487 ALA B CB  1 
ATOM   6153 N N   . PRO B 2 499 ? 63.328  85.091  86.578  1.00 128.18 ? 488 PRO B N   1 
ATOM   6154 C CA  . PRO B 2 499 ? 63.637  85.982  85.455  1.00 128.18 ? 488 PRO B CA  1 
ATOM   6155 C C   . PRO B 2 499 ? 65.070  85.790  84.981  1.00 128.18 ? 488 PRO B C   1 
ATOM   6156 O O   . PRO B 2 499 ? 65.869  85.066  85.576  1.00 128.18 ? 488 PRO B O   1 
ATOM   6157 C CB  . PRO B 2 499 ? 63.423  87.378  86.041  1.00 128.18 ? 488 PRO B CB  1 
ATOM   6158 C CG  . PRO B 2 499 ? 63.697  87.206  87.491  1.00 128.18 ? 488 PRO B CG  1 
ATOM   6159 C CD  . PRO B 2 499 ? 63.197  85.830  87.845  1.00 128.18 ? 488 PRO B CD  1 
ATOM   6160 N N   . VAL B 2 500 ? 65.388  86.460  83.879  1.00 127.22 ? 489 VAL B N   1 
ATOM   6161 C CA  . VAL B 2 500 ? 66.721  86.404  83.292  1.00 127.22 ? 489 VAL B CA  1 
ATOM   6162 C C   . VAL B 2 500 ? 67.469  87.684  83.636  1.00 127.22 ? 489 VAL B C   1 
ATOM   6163 O O   . VAL B 2 500 ? 66.917  88.785  83.535  1.00 127.22 ? 489 VAL B O   1 
ATOM   6164 C CB  . VAL B 2 500 ? 66.643  86.195  81.770  1.00 127.22 ? 489 VAL B CB  1 
ATOM   6165 C CG1 . VAL B 2 500 ? 65.746  87.241  81.127  1.00 127.22 ? 489 VAL B CG1 1 
ATOM   6166 C CG2 . VAL B 2 500 ? 68.034  86.231  81.157  1.00 127.22 ? 489 VAL B CG2 1 
ATOM   6167 N N   . MET B 2 501 ? 68.718  87.539  84.068  1.00 121.79 ? 490 MET B N   1 
ATOM   6168 C CA  . MET B 2 501 ? 69.553  88.701  84.333  1.00 121.79 ? 490 MET B CA  1 
ATOM   6169 C C   . MET B 2 501 ? 69.850  89.437  83.032  1.00 121.79 ? 490 MET B C   1 
ATOM   6170 O O   . MET B 2 501 ? 69.953  88.828  81.964  1.00 121.79 ? 490 MET B O   1 
ATOM   6171 C CB  . MET B 2 501 ? 70.849  88.273  85.018  1.00 121.79 ? 490 MET B CB  1 
ATOM   6172 C CG  . MET B 2 501 ? 71.789  89.409  85.376  1.00 121.79 ? 490 MET B CG  1 
ATOM   6173 S SD  . MET B 2 501 ? 71.080  90.565  86.557  1.00 121.79 ? 490 MET B SD  1 
ATOM   6174 C CE  . MET B 2 501 ? 72.564  91.304  87.232  1.00 121.79 ? 490 MET B CE  1 
ATOM   6175 N N   . LEU B 2 502 ? 69.982  90.758  83.124  1.00 125.32 ? 491 LEU B N   1 
ATOM   6176 C CA  . LEU B 2 502 ? 70.168  91.615  81.954  1.00 125.32 ? 491 LEU B CA  1 
ATOM   6177 C C   . LEU B 2 502 ? 71.617  92.091  81.930  1.00 125.32 ? 491 LEU B C   1 
ATOM   6178 O O   . LEU B 2 502 ? 71.961  93.137  82.481  1.00 125.32 ? 491 LEU B O   1 
ATOM   6179 C CB  . LEU B 2 502 ? 69.182  92.775  81.983  1.00 125.32 ? 491 LEU B CB  1 
ATOM   6180 C CG  . LEU B 2 502 ? 67.772  92.374  82.420  1.00 125.32 ? 491 LEU B CG  1 
ATOM   6181 C CD1 . LEU B 2 502 ? 66.852  93.569  82.417  1.00 125.32 ? 491 LEU B CD1 1 
ATOM   6182 C CD2 . LEU B 2 502 ? 67.222  91.293  81.506  1.00 125.32 ? 491 LEU B CD2 1 
ATOM   6183 N N   . TRP B 2 503 ? 72.473  91.302  81.282  1.00 127.93 ? 492 TRP B N   1 
ATOM   6184 C CA  . TRP B 2 503 ? 73.883  91.658  81.174  1.00 127.93 ? 492 TRP B CA  1 
ATOM   6185 C C   . TRP B 2 503 ? 74.080  92.817  80.205  1.00 127.93 ? 492 TRP B C   1 
ATOM   6186 O O   . TRP B 2 503 ? 74.549  93.895  80.587  1.00 127.93 ? 492 TRP B O   1 
ATOM   6187 C CB  . TRP B 2 503 ? 74.687  90.438  80.728  1.00 127.93 ? 492 TRP B CB  1 
ATOM   6188 C CG  . TRP B 2 503 ? 74.541  89.280  81.649  1.00 127.93 ? 492 TRP B CG  1 
ATOM   6189 C CD1 . TRP B 2 503 ? 73.653  88.253  81.537  1.00 127.93 ? 492 TRP B CD1 1 
ATOM   6190 C CD2 . TRP B 2 503 ? 75.305  89.025  82.828  1.00 127.93 ? 492 TRP B CD2 1 
ATOM   6191 N NE1 . TRP B 2 503 ? 73.815  87.374  82.577  1.00 127.93 ? 492 TRP B NE1 1 
ATOM   6192 C CE2 . TRP B 2 503 ? 74.826  87.824  83.383  1.00 127.93 ? 492 TRP B CE2 1 
ATOM   6193 C CE3 . TRP B 2 503 ? 76.350  89.695  83.468  1.00 127.93 ? 492 TRP B CE3 1 
ATOM   6194 C CZ2 . TRP B 2 503 ? 75.354  87.280  84.546  1.00 127.93 ? 492 TRP B CZ2 1 
ATOM   6195 C CZ3 . TRP B 2 503 ? 76.872  89.154  84.620  1.00 127.93 ? 492 TRP B CZ3 1 
ATOM   6196 C CH2 . TRP B 2 503 ? 76.374  87.959  85.150  1.00 127.93 ? 492 TRP B CH2 1 
ATOM   6197 N N   . ASP B 2 504 ? 73.715  92.611  78.944  1.00 142.08 ? 493 ASP B N   1 
ATOM   6198 C CA  . ASP B 2 504 ? 73.861  93.605  77.893  1.00 142.08 ? 493 ASP B CA  1 
ATOM   6199 C C   . ASP B 2 504 ? 72.580  93.651  77.069  1.00 142.08 ? 493 ASP B C   1 
ATOM   6200 O O   . ASP B 2 504 ? 71.568  93.038  77.421  1.00 142.08 ? 493 ASP B O   1 
ATOM   6201 C CB  . ASP B 2 504 ? 75.093  93.306  77.025  1.00 142.08 ? 493 ASP B CB  1 
ATOM   6202 C CG  . ASP B 2 504 ? 75.077  91.903  76.433  1.00 142.08 ? 493 ASP B CG  1 
ATOM   6203 O OD1 . ASP B 2 504 ? 73.985  91.339  76.213  1.00 142.08 ? 493 ASP B OD1 1 
ATOM   6204 O OD2 . ASP B 2 504 ? 76.174  91.358  76.188  1.00 142.08 ? 493 ASP B OD2 1 
ATOM   6205 N N   . GLU B 2 505 ? 72.626  94.390  75.960  1.00 145.86 ? 494 GLU B N   1 
ATOM   6206 C CA  . GLU B 2 505 ? 71.455  94.504  75.098  1.00 145.86 ? 494 GLU B CA  1 
ATOM   6207 C C   . GLU B 2 505 ? 71.032  93.162  74.514  1.00 145.86 ? 494 GLU B C   1 
ATOM   6208 O O   . GLU B 2 505 ? 69.880  93.019  74.089  1.00 145.86 ? 494 GLU B O   1 
ATOM   6209 C CB  . GLU B 2 505 ? 71.730  95.501  73.972  1.00 145.86 ? 494 GLU B CB  1 
ATOM   6210 C CG  . GLU B 2 505 ? 71.996  96.921  74.448  1.00 145.86 ? 494 GLU B CG  1 
ATOM   6211 C CD  . GLU B 2 505 ? 70.728  97.664  74.823  1.00 145.86 ? 494 GLU B CD  1 
ATOM   6212 O OE1 . GLU B 2 505 ? 70.387  98.645  74.129  1.00 145.86 ? 494 GLU B OE1 1 
ATOM   6213 O OE2 . GLU B 2 505 ? 70.079  97.277  75.817  1.00 145.86 ? 494 GLU B OE2 1 
ATOM   6214 N N   . SER B 2 506 ? 71.930  92.178  74.486  1.00 146.43 ? 495 SER B N   1 
ATOM   6215 C CA  . SER B 2 506 ? 71.633  90.853  73.963  1.00 146.43 ? 495 SER B CA  1 
ATOM   6216 C C   . SER B 2 506 ? 71.268  89.862  75.062  1.00 146.43 ? 495 SER B C   1 
ATOM   6217 O O   . SER B 2 506 ? 71.295  88.649  74.828  1.00 146.43 ? 495 SER B O   1 
ATOM   6218 C CB  . SER B 2 506 ? 72.819  90.329  73.153  1.00 146.43 ? 495 SER B CB  1 
ATOM   6219 O OG  . SER B 2 506 ? 73.967  90.179  73.970  1.00 146.43 ? 495 SER B OG  1 
ATOM   6220 N N   . SER B 2 507 ? 70.932  90.353  76.257  1.00 142.44 ? 496 SER B N   1 
ATOM   6221 C CA  . SER B 2 507 ? 70.597  89.453  77.355  1.00 142.44 ? 496 SER B CA  1 
ATOM   6222 C C   . SER B 2 507 ? 69.302  88.701  77.080  1.00 142.44 ? 496 SER B C   1 
ATOM   6223 O O   . SER B 2 507 ? 69.176  87.520  77.421  1.00 142.44 ? 496 SER B O   1 
ATOM   6224 C CB  . SER B 2 507 ? 70.491  90.235  78.661  1.00 142.44 ? 496 SER B CB  1 
ATOM   6225 O OG  . SER B 2 507 ? 71.775  90.573  79.147  1.00 142.44 ? 496 SER B OG  1 
ATOM   6226 N N   . PHE B 2 508 ? 68.327  89.369  76.469  1.00 150.01 ? 497 PHE B N   1 
ATOM   6227 C CA  . PHE B 2 508 ? 67.067  88.730  76.107  1.00 150.01 ? 497 PHE B CA  1 
ATOM   6228 C C   . PHE B 2 508 ? 66.905  88.782  74.595  1.00 150.01 ? 497 PHE B C   1 
ATOM   6229 O O   . PHE B 2 508 ? 66.345  89.753  74.064  1.00 150.01 ? 497 PHE B O   1 
ATOM   6230 C CB  . PHE B 2 508 ? 65.888  89.415  76.802  1.00 150.01 ? 497 PHE B CB  1 
ATOM   6231 C CG  . PHE B 2 508 ? 64.627  88.602  76.792  1.00 150.01 ? 497 PHE B CG  1 
ATOM   6232 C CD1 . PHE B 2 508 ? 64.591  87.351  77.386  1.00 150.01 ? 497 PHE B CD1 1 
ATOM   6233 C CD2 . PHE B 2 508 ? 63.479  89.086  76.191  1.00 150.01 ? 497 PHE B CD2 1 
ATOM   6234 C CE1 . PHE B 2 508 ? 63.434  86.598  77.378  1.00 150.01 ? 497 PHE B CE1 1 
ATOM   6235 C CE2 . PHE B 2 508 ? 62.318  88.337  76.179  1.00 150.01 ? 497 PHE B CE2 1 
ATOM   6236 C CZ  . PHE B 2 508 ? 62.296  87.092  76.775  1.00 150.01 ? 497 PHE B CZ  1 
ATOM   6237 N N   . PRO B 2 509 ? 67.382  87.776  73.858  1.00 152.98 ? 498 PRO B N   1 
ATOM   6238 C CA  . PRO B 2 509 ? 67.286  87.829  72.390  1.00 152.98 ? 498 PRO B CA  1 
ATOM   6239 C C   . PRO B 2 509 ? 65.861  87.856  71.872  1.00 152.98 ? 498 PRO B C   1 
ATOM   6240 O O   . PRO B 2 509 ? 65.642  88.282  70.731  1.00 152.98 ? 498 PRO B O   1 
ATOM   6241 C CB  . PRO B 2 509 ? 68.020  86.557  71.944  1.00 152.98 ? 498 PRO B CB  1 
ATOM   6242 C CG  . PRO B 2 509 ? 67.974  85.653  73.133  1.00 152.98 ? 498 PRO B CG  1 
ATOM   6243 C CD  . PRO B 2 509 ? 68.049  86.551  74.328  1.00 152.98 ? 498 PRO B CD  1 
ATOM   6244 N N   . ASP B 2 510 ? 64.888  87.412  72.661  1.00 155.48 ? 499 ASP B N   1 
ATOM   6245 C CA  . ASP B 2 510 ? 63.496  87.511  72.254  1.00 155.48 ? 499 ASP B CA  1 
ATOM   6246 C C   . ASP B 2 510 ? 63.042  88.967  72.306  1.00 155.48 ? 499 ASP B C   1 
ATOM   6247 O O   . ASP B 2 510 ? 63.453  89.733  73.181  1.00 155.48 ? 499 ASP B O   1 
ATOM   6248 C CB  . ASP B 2 510 ? 62.616  86.645  73.155  1.00 155.48 ? 499 ASP B CB  1 
ATOM   6249 C CG  . ASP B 2 510 ? 61.173  86.590  72.691  1.00 155.48 ? 499 ASP B CG  1 
ATOM   6250 O OD1 . ASP B 2 510 ? 60.884  87.056  71.569  1.00 155.48 ? 499 ASP B OD1 1 
ATOM   6251 O OD2 . ASP B 2 510 ? 60.325  86.082  73.453  1.00 155.48 ? 499 ASP B OD2 1 
ATOM   6252 N N   . ILE B 2 511 ? 62.180  89.332  71.357  1.00 156.73 ? 500 ILE B N   1 
ATOM   6253 C CA  . ILE B 2 511 ? 61.666  90.692  71.158  1.00 156.73 ? 500 ILE B CA  1 
ATOM   6254 C C   . ILE B 2 511 ? 62.725  91.755  71.453  1.00 156.73 ? 500 ILE B C   1 
ATOM   6255 O O   . ILE B 2 511 ? 62.487  92.669  72.257  1.00 156.73 ? 500 ILE B O   1 
ATOM   6256 C CB  . ILE B 2 511 ? 60.370  90.914  71.967  1.00 156.73 ? 500 ILE B CB  1 
ATOM   6257 C CG1 . ILE B 2 511 ? 60.595  90.867  73.485  1.00 156.73 ? 500 ILE B CG1 1 
ATOM   6258 C CG2 . ILE B 2 511 ? 59.302  89.910  71.553  1.00 156.73 ? 500 ILE B CG2 1 
ATOM   6259 C CD1 . ILE B 2 511 ? 59.461  91.460  74.286  1.00 156.73 ? 500 ILE B CD1 1 
ATOM   6260 N N   . PRO B 2 512 ? 63.887  91.709  70.801  1.00 154.13 ? 501 PRO B N   1 
ATOM   6261 C CA  . PRO B 2 512 ? 64.948  92.667  71.125  1.00 154.13 ? 501 PRO B CA  1 
ATOM   6262 C C   . PRO B 2 512 ? 64.562  94.084  70.730  1.00 154.13 ? 501 PRO B C   1 
ATOM   6263 O O   . PRO B 2 512 ? 63.611  94.319  69.981  1.00 154.13 ? 501 PRO B O   1 
ATOM   6264 C CB  . PRO B 2 512 ? 66.141  92.169  70.304  1.00 154.13 ? 501 PRO B CB  1 
ATOM   6265 C CG  . PRO B 2 512 ? 65.524  91.488  69.137  1.00 154.13 ? 501 PRO B CG  1 
ATOM   6266 C CD  . PRO B 2 512 ? 64.219  90.902  69.612  1.00 154.13 ? 501 PRO B CD  1 
ATOM   6267 N N   . GLY B 2 513 ? 65.325  95.039  71.256  1.00 149.62 ? 502 GLY B N   1 
ATOM   6268 C CA  . GLY B 2 513 ? 65.077  96.444  71.041  1.00 149.62 ? 502 GLY B CA  1 
ATOM   6269 C C   . GLY B 2 513 ? 64.414  97.149  72.205  1.00 149.62 ? 502 GLY B C   1 
ATOM   6270 O O   . GLY B 2 513 ? 64.643  98.349  72.397  1.00 149.62 ? 502 GLY B O   1 
ATOM   6271 N N   . ALA B 2 514 ? 63.598  96.437  72.985  1.00 148.14 ? 503 ALA B N   1 
ATOM   6272 C CA  . ALA B 2 514 ? 62.983  97.024  74.166  1.00 148.14 ? 503 ALA B CA  1 
ATOM   6273 C C   . ALA B 2 514 ? 63.931  97.064  75.355  1.00 148.14 ? 503 ALA B C   1 
ATOM   6274 O O   . ALA B 2 514 ? 63.691  97.826  76.298  1.00 148.14 ? 503 ALA B O   1 
ATOM   6275 C CB  . ALA B 2 514 ? 61.716  96.252  74.542  1.00 148.14 ? 503 ALA B CB  1 
ATOM   6276 N N   . VAL B 2 515 ? 64.994  96.262  75.333  1.00 144.96 ? 504 VAL B N   1 
ATOM   6277 C CA  . VAL B 2 515 ? 65.989  96.291  76.398  1.00 144.96 ? 504 VAL B CA  1 
ATOM   6278 C C   . VAL B 2 515 ? 66.691  97.642  76.374  1.00 144.96 ? 504 VAL B C   1 
ATOM   6279 O O   . VAL B 2 515 ? 67.404  97.970  75.418  1.00 144.96 ? 504 VAL B O   1 
ATOM   6280 C CB  . VAL B 2 515 ? 66.991  95.140  76.242  1.00 144.96 ? 504 VAL B CB  1 
ATOM   6281 C CG1 . VAL B 2 515 ? 67.988  95.146  77.386  1.00 144.96 ? 504 VAL B CG1 1 
ATOM   6282 C CG2 . VAL B 2 515 ? 66.260  93.808  76.168  1.00 144.96 ? 504 VAL B CG2 1 
ATOM   6283 N N   . SER B 2 516 ? 66.488  98.433  77.423  1.00 138.84 ? 505 SER B N   1 
ATOM   6284 C CA  . SER B 2 516 ? 67.063  99.769  77.493  1.00 138.84 ? 505 SER B CA  1 
ATOM   6285 C C   . SER B 2 516 ? 68.525  99.676  77.925  1.00 138.84 ? 505 SER B C   1 
ATOM   6286 O O   . SER B 2 516 ? 69.076  98.590  78.122  1.00 138.84 ? 505 SER B O   1 
ATOM   6287 C CB  . SER B 2 516 ? 66.244  100.649 78.434  1.00 138.84 ? 505 SER B CB  1 
ATOM   6288 O OG  . SER B 2 516 ? 66.656  100.476 79.778  1.00 138.84 ? 505 SER B OG  1 
ATOM   6289 N N   . ALA B 2 517 ? 69.173  100.830 78.080  1.00 134.74 ? 506 ALA B N   1 
ATOM   6290 C CA  . ALA B 2 517 ? 70.562  100.886 78.515  1.00 134.74 ? 506 ALA B CA  1 
ATOM   6291 C C   . ALA B 2 517 ? 70.709  101.056 80.018  1.00 134.74 ? 506 ALA B C   1 
ATOM   6292 O O   . ALA B 2 517 ? 71.699  100.588 80.589  1.00 134.74 ? 506 ALA B O   1 
ATOM   6293 C CB  . ALA B 2 517 ? 71.296  102.028 77.806  1.00 134.74 ? 506 ALA B CB  1 
ATOM   6294 N N   . ASN B 2 518 ? 69.752  101.712 80.671  1.00 132.90 ? 507 ASN B N   1 
ATOM   6295 C CA  . ASN B 2 518 ? 69.764  101.849 82.120  1.00 132.90 ? 507 ASN B CA  1 
ATOM   6296 C C   . ASN B 2 518 ? 69.226  100.615 82.830  1.00 132.90 ? 507 ASN B C   1 
ATOM   6297 O O   . ASN B 2 518 ? 69.220  100.584 84.064  1.00 132.90 ? 507 ASN B O   1 
ATOM   6298 C CB  . ASN B 2 518 ? 68.948  103.072 82.541  1.00 132.90 ? 507 ASN B CB  1 
ATOM   6299 C CG  . ASN B 2 518 ? 67.524  103.024 82.028  1.00 132.90 ? 507 ASN B CG  1 
ATOM   6300 O OD1 . ASN B 2 518 ? 67.262  102.505 80.943  1.00 132.90 ? 507 ASN B OD1 1 
ATOM   6301 N ND2 . ASN B 2 518 ? 66.594  103.561 82.808  1.00 132.90 ? 507 ASN B ND2 1 
ATOM   6302 N N   . MET B 2 519 ? 68.770  99.610  82.088  1.00 134.92 ? 508 MET B N   1 
ATOM   6303 C CA  . MET B 2 519 ? 68.173  98.422  82.678  1.00 134.92 ? 508 MET B CA  1 
ATOM   6304 C C   . MET B 2 519 ? 69.130  97.236  82.708  1.00 134.92 ? 508 MET B C   1 
ATOM   6305 O O   . MET B 2 519 ? 68.854  96.250  83.399  1.00 134.92 ? 508 MET B O   1 
ATOM   6306 C CB  . MET B 2 519 ? 66.892  98.066  81.910  1.00 134.92 ? 508 MET B CB  1 
ATOM   6307 C CG  . MET B 2 519 ? 66.030  96.989  82.535  1.00 134.92 ? 508 MET B CG  1 
ATOM   6308 S SD  . MET B 2 519 ? 64.512  96.711  81.604  1.00 134.92 ? 508 MET B SD  1 
ATOM   6309 C CE  . MET B 2 519 ? 65.147  95.907  80.135  1.00 134.92 ? 508 MET B CE  1 
ATOM   6310 N N   . THR B 2 520 ? 70.251  97.314  81.998  1.00 131.36 ? 509 THR B N   1 
ATOM   6311 C CA  . THR B 2 520 ? 71.265  96.271  82.010  1.00 131.36 ? 509 THR B CA  1 
ATOM   6312 C C   . THR B 2 520 ? 72.375  96.629  82.989  1.00 131.36 ? 509 THR B C   1 
ATOM   6313 O O   . THR B 2 520 ? 72.557  97.794  83.352  1.00 131.36 ? 509 THR B O   1 
ATOM   6314 C CB  . THR B 2 520 ? 71.862  96.063  80.617  1.00 131.36 ? 509 THR B CB  1 
ATOM   6315 O OG1 . THR B 2 520 ? 72.738  97.153  80.305  1.00 131.36 ? 509 THR B OG1 1 
ATOM   6316 C CG2 . THR B 2 520 ? 70.764  95.991  79.574  1.00 131.36 ? 509 THR B CG2 1 
ATOM   6317 N N   . VAL B 2 521 ? 73.121  95.607  83.416  1.00 125.39 ? 510 VAL B N   1 
ATOM   6318 C CA  . VAL B 2 521 ? 74.221  95.832  84.351  1.00 125.39 ? 510 VAL B CA  1 
ATOM   6319 C C   . VAL B 2 521 ? 75.312  96.671  83.699  1.00 125.39 ? 510 VAL B C   1 
ATOM   6320 O O   . VAL B 2 521 ? 76.000  97.453  84.368  1.00 125.39 ? 510 VAL B O   1 
ATOM   6321 C CB  . VAL B 2 521 ? 74.765  94.488  84.872  1.00 125.39 ? 510 VAL B CB  1 
ATOM   6322 C CG1 . VAL B 2 521 ? 75.252  93.627  83.730  1.00 125.39 ? 510 VAL B CG1 1 
ATOM   6323 C CG2 . VAL B 2 521 ? 75.881  94.714  85.876  1.00 125.39 ? 510 VAL B CG2 1 
ATOM   6324 N N   . LYS B 2 522 ? 75.477  96.538  82.381  1.00 127.99 ? 511 LYS B N   1 
ATOM   6325 C CA  . LYS B 2 522 ? 76.558  97.236  81.692  1.00 127.99 ? 511 LYS B CA  1 
ATOM   6326 C C   . LYS B 2 522 ? 76.357  98.745  81.742  1.00 127.99 ? 511 LYS B C   1 
ATOM   6327 O O   . LYS B 2 522 ? 77.241  99.486  82.185  1.00 127.99 ? 511 LYS B O   1 
ATOM   6328 C CB  . LYS B 2 522 ? 76.654  96.751  80.246  1.00 127.99 ? 511 LYS B CB  1 
ATOM   6329 C CG  . LYS B 2 522 ? 78.045  96.862  79.648  1.00 127.99 ? 511 LYS B CG  1 
ATOM   6330 C CD  . LYS B 2 522 ? 78.197  95.954  78.441  1.00 127.99 ? 511 LYS B CD  1 
ATOM   6331 C CE  . LYS B 2 522 ? 77.293  96.394  77.301  1.00 127.99 ? 511 LYS B CE  1 
ATOM   6332 N NZ  . LYS B 2 522 ? 77.842  97.577  76.584  1.00 127.99 ? 511 LYS B NZ  1 
ATOM   6333 N N   . GLY B 2 523 ? 75.193  99.220  81.294  1.00 128.68 ? 512 GLY B N   1 
ATOM   6334 C CA  . GLY B 2 523 ? 74.929  100.647 81.283  1.00 128.68 ? 512 GLY B CA  1 
ATOM   6335 C C   . GLY B 2 523 ? 74.883  101.279 82.657  1.00 128.68 ? 512 GLY B C   1 
ATOM   6336 O O   . GLY B 2 523 ? 75.123  102.485 82.781  1.00 128.68 ? 512 GLY B O   1 
ATOM   6337 N N   . GLN B 2 524 ? 74.581  100.495 83.691  1.00 123.78 ? 513 GLN B N   1 
ATOM   6338 C CA  . GLN B 2 524 ? 74.517  101.010 85.051  1.00 123.78 ? 513 GLN B CA  1 
ATOM   6339 C C   . GLN B 2 524 ? 75.864  101.003 85.756  1.00 123.78 ? 513 GLN B C   1 
ATOM   6340 O O   . GLN B 2 524 ? 76.038  101.739 86.733  1.00 123.78 ? 513 GLN B O   1 
ATOM   6341 C CB  . GLN B 2 524 ? 73.515  100.198 85.875  1.00 123.78 ? 513 GLN B CB  1 
ATOM   6342 C CG  . GLN B 2 524 ? 72.069  100.433 85.486  1.00 123.78 ? 513 GLN B CG  1 
ATOM   6343 C CD  . GLN B 2 524 ? 71.104  99.658  86.355  1.00 123.78 ? 513 GLN B CD  1 
ATOM   6344 O OE1 . GLN B 2 524 ? 71.512  98.831  87.169  1.00 123.78 ? 513 GLN B OE1 1 
ATOM   6345 N NE2 . GLN B 2 524 ? 69.814  99.922  86.189  1.00 123.78 ? 513 GLN B NE2 1 
ATOM   6346 N N   . SER B 2 525 ? 76.816  100.195 85.286  1.00 124.79 ? 514 SER B N   1 
ATOM   6347 C CA  . SER B 2 525 ? 78.097  100.061 85.968  1.00 124.79 ? 514 SER B CA  1 
ATOM   6348 C C   . SER B 2 525 ? 78.920  101.342 85.940  1.00 124.79 ? 514 SER B C   1 
ATOM   6349 O O   . SER B 2 525 ? 79.800  101.514 86.789  1.00 124.79 ? 514 SER B O   1 
ATOM   6350 C CB  . SER B 2 525 ? 78.898  98.918  85.347  1.00 124.79 ? 514 SER B CB  1 
ATOM   6351 O OG  . SER B 2 525 ? 78.076  97.787  85.124  1.00 124.79 ? 514 SER B OG  1 
ATOM   6352 N N   . GLU B 2 526 ? 78.658  102.241 84.993  1.00 127.16 ? 515 GLU B N   1 
ATOM   6353 C CA  . GLU B 2 526 ? 79.430  103.471 84.868  1.00 127.16 ? 515 GLU B CA  1 
ATOM   6354 C C   . GLU B 2 526 ? 78.769  104.670 85.531  1.00 127.16 ? 515 GLU B C   1 
ATOM   6355 O O   . GLU B 2 526 ? 79.466  105.623 85.895  1.00 127.16 ? 515 GLU B O   1 
ATOM   6356 C CB  . GLU B 2 526 ? 79.678  103.796 83.391  1.00 127.16 ? 515 GLU B CB  1 
ATOM   6357 C CG  . GLU B 2 526 ? 80.195  102.627 82.572  1.00 127.16 ? 515 GLU B CG  1 
ATOM   6358 C CD  . GLU B 2 526 ? 79.094  101.925 81.804  1.00 127.16 ? 515 GLU B CD  1 
ATOM   6359 O OE1 . GLU B 2 526 ? 77.920  102.327 81.943  1.00 127.16 ? 515 GLU B OE1 1 
ATOM   6360 O OE2 . GLU B 2 526 ? 79.403  100.972 81.058  1.00 127.16 ? 515 GLU B OE2 1 
ATOM   6361 N N   . ASP B 2 527 ? 77.455  104.651 85.694  1.00 126.35 ? 516 ASP B N   1 
ATOM   6362 C CA  . ASP B 2 527 ? 76.747  105.804 86.234  1.00 126.35 ? 516 ASP B CA  1 
ATOM   6363 C C   . ASP B 2 527 ? 76.778  105.787 87.756  1.00 126.35 ? 516 ASP B C   1 
ATOM   6364 O O   . ASP B 2 527 ? 76.257  104.844 88.365  1.00 126.35 ? 516 ASP B O   1 
ATOM   6365 C CB  . ASP B 2 527 ? 75.307  105.812 85.737  1.00 126.35 ? 516 ASP B CB  1 
ATOM   6366 C CG  . ASP B 2 527 ? 75.215  105.786 84.227  1.00 126.35 ? 516 ASP B CG  1 
ATOM   6367 O OD1 . ASP B 2 527 ? 76.275  105.799 83.568  1.00 126.35 ? 516 ASP B OD1 1 
ATOM   6368 O OD2 . ASP B 2 527 ? 74.085  105.751 83.698  1.00 126.35 ? 516 ASP B OD2 1 
ATOM   6369 N N   . PRO B 2 528 ? 77.370  106.791 88.409  1.00 127.42 ? 517 PRO B N   1 
ATOM   6370 C CA  . PRO B 2 528 ? 77.304  106.855 89.878  1.00 127.42 ? 517 PRO B CA  1 
ATOM   6371 C C   . PRO B 2 528 ? 75.907  107.121 90.409  1.00 127.42 ? 517 PRO B C   1 
ATOM   6372 O O   . PRO B 2 528 ? 75.616  106.735 91.549  1.00 127.42 ? 517 PRO B O   1 
ATOM   6373 C CB  . PRO B 2 528 ? 78.257  108.008 90.230  1.00 127.42 ? 517 PRO B CB  1 
ATOM   6374 C CG  . PRO B 2 528 ? 79.047  108.278 88.982  1.00 127.42 ? 517 PRO B CG  1 
ATOM   6375 C CD  . PRO B 2 528 ? 78.167  107.889 87.842  1.00 127.42 ? 517 PRO B CD  1 
ATOM   6376 N N   . GLY B 2 529 ? 75.040  107.760 89.628  1.00 124.16 ? 518 GLY B N   1 
ATOM   6377 C CA  . GLY B 2 529 ? 73.681  108.013 90.058  1.00 124.16 ? 518 GLY B CA  1 
ATOM   6378 C C   . GLY B 2 529 ? 72.737  106.897 89.669  1.00 124.16 ? 518 GLY B C   1 
ATOM   6379 O O   . GLY B 2 529 ? 71.520  107.095 89.597  1.00 124.16 ? 518 GLY B O   1 
ATOM   6380 N N   . SER B 2 530 ? 73.291  105.717 89.410  1.00 121.01 ? 519 SER B N   1 
ATOM   6381 C CA  . SER B 2 530 ? 72.499  104.543 89.085  1.00 121.01 ? 519 SER B CA  1 
ATOM   6382 C C   . SER B 2 530 ? 72.163  103.780 90.365  1.00 121.01 ? 519 SER B C   1 
ATOM   6383 O O   . SER B 2 530 ? 72.408  104.249 91.479  1.00 121.01 ? 519 SER B O   1 
ATOM   6384 C CB  . SER B 2 530 ? 73.243  103.661 88.088  1.00 121.01 ? 519 SER B CB  1 
ATOM   6385 O OG  . SER B 2 530 ? 72.576  102.423 87.927  1.00 121.01 ? 519 SER B OG  1 
ATOM   6386 N N   . LEU B 2 531 ? 71.595  102.586 90.212  1.00 115.14 ? 520 LEU B N   1 
ATOM   6387 C CA  . LEU B 2 531 ? 71.298  101.726 91.350  1.00 115.14 ? 520 LEU B CA  1 
ATOM   6388 C C   . LEU B 2 531 ? 72.430  100.746 91.632  1.00 115.14 ? 520 LEU B C   1 
ATOM   6389 O O   . LEU B 2 531 ? 72.748  100.484 92.797  1.00 115.14 ? 520 LEU B O   1 
ATOM   6390 C CB  . LEU B 2 531 ? 69.993  100.965 91.108  1.00 115.14 ? 520 LEU B CB  1 
ATOM   6391 C CG  . LEU B 2 531 ? 69.622  99.904  92.142  1.00 115.14 ? 520 LEU B CG  1 
ATOM   6392 C CD1 . LEU B 2 531 ? 69.514  100.518 93.526  1.00 115.14 ? 520 LEU B CD1 1 
ATOM   6393 C CD2 . LEU B 2 531 ? 68.324  99.219  91.759  1.00 115.14 ? 520 LEU B CD2 1 
ATOM   6394 N N   . LEU B 2 532 ? 73.039  100.193 90.581  1.00 113.09 ? 521 LEU B N   1 
ATOM   6395 C CA  . LEU B 2 532 ? 74.156  99.278  90.775  1.00 113.09 ? 521 LEU B CA  1 
ATOM   6396 C C   . LEU B 2 532 ? 75.333  99.978  91.440  1.00 113.09 ? 521 LEU B C   1 
ATOM   6397 O O   . LEU B 2 532 ? 76.074  99.364  92.215  1.00 113.09 ? 521 LEU B O   1 
ATOM   6398 C CB  . LEU B 2 532 ? 74.571  98.672  89.438  1.00 113.09 ? 521 LEU B CB  1 
ATOM   6399 C CG  . LEU B 2 532 ? 75.875  97.881  89.452  1.00 113.09 ? 521 LEU B CG  1 
ATOM   6400 C CD1 . LEU B 2 532 ? 75.664  96.568  90.160  1.00 113.09 ? 521 LEU B CD1 1 
ATOM   6401 C CD2 . LEU B 2 532 ? 76.376  97.650  88.044  1.00 113.09 ? 521 LEU B CD2 1 
ATOM   6402 N N   . SER B 2 533 ? 75.514  101.271 91.165  1.00 118.72 ? 522 SER B N   1 
ATOM   6403 C CA  . SER B 2 533 ? 76.544  102.028 91.866  1.00 118.72 ? 522 SER B CA  1 
ATOM   6404 C C   . SER B 2 533 ? 76.225  102.130 93.350  1.00 118.72 ? 522 SER B C   1 
ATOM   6405 O O   . SER B 2 533 ? 77.120  102.019 94.197  1.00 118.72 ? 522 SER B O   1 
ATOM   6406 C CB  . SER B 2 533 ? 76.688  103.418 91.248  1.00 118.72 ? 522 SER B CB  1 
ATOM   6407 O OG  . SER B 2 533 ? 75.512  104.184 91.439  1.00 118.72 ? 522 SER B OG  1 
ATOM   6408 N N   . LEU B 2 534 ? 74.949  102.333 93.684  1.00 112.39 ? 523 LEU B N   1 
ATOM   6409 C CA  . LEU B 2 534 ? 74.534  102.327 95.082  1.00 112.39 ? 523 LEU B CA  1 
ATOM   6410 C C   . LEU B 2 534 ? 74.837  100.985 95.731  1.00 112.39 ? 523 LEU B C   1 
ATOM   6411 O O   . LEU B 2 534 ? 75.355  100.925 96.850  1.00 112.39 ? 523 LEU B O   1 
ATOM   6412 C CB  . LEU B 2 534 ? 73.043  102.646 95.181  1.00 112.39 ? 523 LEU B CB  1 
ATOM   6413 C CG  . LEU B 2 534 ? 72.401  102.449 96.551  1.00 112.39 ? 523 LEU B CG  1 
ATOM   6414 C CD1 . LEU B 2 534 ? 72.958  103.456 97.534  1.00 112.39 ? 523 LEU B CD1 1 
ATOM   6415 C CD2 . LEU B 2 534 ? 70.890  102.563 96.454  1.00 112.39 ? 523 LEU B CD2 1 
ATOM   6416 N N   . PHE B 2 535 ? 74.520  99.894  95.031  1.00 105.78 ? 524 PHE B N   1 
ATOM   6417 C CA  . PHE B 2 535 ? 74.784  98.557  95.554  1.00 105.78 ? 524 PHE B CA  1 
ATOM   6418 C C   . PHE B 2 535 ? 76.271  98.354  95.811  1.00 105.78 ? 524 PHE B C   1 
ATOM   6419 O O   . PHE B 2 535 ? 76.667  97.842  96.863  1.00 105.78 ? 524 PHE B O   1 
ATOM   6420 C CB  . PHE B 2 535 ? 74.251  97.510  94.575  1.00 105.78 ? 524 PHE B CB  1 
ATOM   6421 C CG  . PHE B 2 535 ? 74.230  96.108  95.118  1.00 105.78 ? 524 PHE B CG  1 
ATOM   6422 C CD1 . PHE B 2 535 ? 75.404  95.414  95.349  1.00 105.78 ? 524 PHE B CD1 1 
ATOM   6423 C CD2 . PHE B 2 535 ? 73.031  95.480  95.383  1.00 105.78 ? 524 PHE B CD2 1 
ATOM   6424 C CE1 . PHE B 2 535 ? 75.380  94.129  95.840  1.00 105.78 ? 524 PHE B CE1 1 
ATOM   6425 C CE2 . PHE B 2 535 ? 73.002  94.191  95.871  1.00 105.78 ? 524 PHE B CE2 1 
ATOM   6426 C CZ  . PHE B 2 535 ? 74.178  93.516  96.102  1.00 105.78 ? 524 PHE B CZ  1 
ATOM   6427 N N   . ARG B 2 536 ? 77.110  98.734  94.849  1.00 108.40 ? 525 ARG B N   1 
ATOM   6428 C CA  . ARG B 2 536 ? 78.545  98.525  95.005  1.00 108.40 ? 525 ARG B CA  1 
ATOM   6429 C C   . ARG B 2 536 ? 79.109  99.369  96.140  1.00 108.40 ? 525 ARG B C   1 
ATOM   6430 O O   . ARG B 2 536 ? 79.885  98.868  96.960  1.00 108.40 ? 525 ARG B O   1 
ATOM   6431 C CB  . ARG B 2 536 ? 79.264  98.824  93.692  1.00 108.40 ? 525 ARG B CB  1 
ATOM   6432 C CG  . ARG B 2 536 ? 78.845  97.902  92.562  1.00 108.40 ? 525 ARG B CG  1 
ATOM   6433 C CD  . ARG B 2 536 ? 79.143  98.489  91.196  1.00 108.40 ? 525 ARG B CD  1 
ATOM   6434 N NE  . ARG B 2 536 ? 79.040  97.470  90.158  1.00 108.40 ? 525 ARG B NE  1 
ATOM   6435 C CZ  . ARG B 2 536 ? 80.081  96.844  89.623  1.00 108.40 ? 525 ARG B CZ  1 
ATOM   6436 N NH1 . ARG B 2 536 ? 81.309  97.135  90.026  1.00 108.40 ? 525 ARG B NH1 1 
ATOM   6437 N NH2 . ARG B 2 536 ? 79.895  95.925  88.686  1.00 108.40 ? 525 ARG B NH2 1 
ATOM   6438 N N   . ARG B 2 537 ? 78.710  100.639 96.228  1.00 113.22 ? 526 ARG B N   1 
ATOM   6439 C CA  . ARG B 2 537 ? 79.226  101.489 97.296  1.00 113.22 ? 526 ARG B CA  1 
ATOM   6440 C C   . ARG B 2 537 ? 78.752  101.010 98.664  1.00 113.22 ? 526 ARG B C   1 
ATOM   6441 O O   . ARG B 2 537 ? 79.522  101.013 99.633  1.00 113.22 ? 526 ARG B O   1 
ATOM   6442 C CB  . ARG B 2 537 ? 78.816  102.940 97.051  1.00 113.22 ? 526 ARG B CB  1 
ATOM   6443 C CG  . ARG B 2 537 ? 79.414  103.527 95.783  1.00 113.22 ? 526 ARG B CG  1 
ATOM   6444 C CD  . ARG B 2 537 ? 79.030  104.980 95.607  1.00 113.22 ? 526 ARG B CD  1 
ATOM   6445 N NE  . ARG B 2 537 ? 79.590  105.820 96.660  1.00 113.22 ? 526 ARG B NE  1 
ATOM   6446 C CZ  . ARG B 2 537 ? 79.100  107.005 97.003  1.00 113.22 ? 526 ARG B CZ  1 
ATOM   6447 N NH1 . ARG B 2 537 ? 78.038  107.490 96.375  1.00 113.22 ? 526 ARG B NH1 1 
ATOM   6448 N NH2 . ARG B 2 537 ? 79.670  107.705 97.974  1.00 113.22 ? 526 ARG B NH2 1 
ATOM   6449 N N   . LEU B 2 538 ? 77.495  100.573 98.761  1.00 104.64 ? 527 LEU B N   1 
ATOM   6450 C CA  . LEU B 2 538 ? 76.998  100.031 100.020 1.00 104.64 ? 527 LEU B CA  1 
ATOM   6451 C C   . LEU B 2 538 ? 77.757  98.773  100.417 1.00 104.64 ? 527 LEU B C   1 
ATOM   6452 O O   . LEU B 2 538 ? 78.335  98.705  101.506 1.00 104.64 ? 527 LEU B O   1 
ATOM   6453 C CB  . LEU B 2 538 ? 75.503  99.751  99.915  1.00 104.64 ? 527 LEU B CB  1 
ATOM   6454 C CG  . LEU B 2 538 ? 74.669  101.007 100.123 1.00 104.64 ? 527 LEU B CG  1 
ATOM   6455 C CD1 . LEU B 2 538 ? 73.195  100.692 100.025 1.00 104.64 ? 527 LEU B CD1 1 
ATOM   6456 C CD2 . LEU B 2 538 ? 75.008  101.614 101.467 1.00 104.64 ? 527 LEU B CD2 1 
ATOM   6457 N N   . SER B 2 539 ? 77.760  97.758  99.549  1.00 97.46  ? 528 SER B N   1 
ATOM   6458 C CA  . SER B 2 539 ? 78.460  96.519  99.860  1.00 97.46  ? 528 SER B CA  1 
ATOM   6459 C C   . SER B 2 539 ? 79.958  96.719  100.028 1.00 97.46  ? 528 SER B C   1 
ATOM   6460 O O   . SER B 2 539 ? 80.636  95.816  100.524 1.00 97.46  ? 528 SER B O   1 
ATOM   6461 C CB  . SER B 2 539 ? 78.200  95.483  98.773  1.00 97.46  ? 528 SER B CB  1 
ATOM   6462 O OG  . SER B 2 539 ? 78.912  94.290  99.038  1.00 97.46  ? 528 SER B OG  1 
ATOM   6463 N N   . ASP B 2 540 ? 80.492  97.869  99.621  1.00 100.07 ? 529 ASP B N   1 
ATOM   6464 C CA  . ASP B 2 540 ? 81.860  98.197  99.994  1.00 100.07 ? 529 ASP B CA  1 
ATOM   6465 C C   . ASP B 2 540 ? 81.917  98.750  101.410 1.00 100.07 ? 529 ASP B C   1 
ATOM   6466 O O   . ASP B 2 540 ? 82.815  98.398  102.180 1.00 100.07 ? 529 ASP B O   1 
ATOM   6467 C CB  . ASP B 2 540 ? 82.449  99.201  99.006  1.00 100.07 ? 529 ASP B CB  1 
ATOM   6468 C CG  . ASP B 2 540 ? 83.869  99.593  99.353  1.00 100.07 ? 529 ASP B CG  1 
ATOM   6469 O OD1 . ASP B 2 540 ? 84.574  98.779  99.986  1.00 100.07 ? 529 ASP B OD1 1 
ATOM   6470 O OD2 . ASP B 2 540 ? 84.281  100.717 98.993  1.00 100.07 ? 529 ASP B OD2 1 
ATOM   6471 N N   . GLN B 2 541 ? 80.962  99.608  101.772 1.00 100.90 ? 530 GLN B N   1 
ATOM   6472 C CA  . GLN B 2 541 ? 80.905  100.122 103.136 1.00 100.90 ? 530 GLN B CA  1 
ATOM   6473 C C   . GLN B 2 541 ? 80.473  99.069  104.146 1.00 100.90 ? 530 GLN B C   1 
ATOM   6474 O O   . GLN B 2 541 ? 80.548  99.323  105.352 1.00 100.90 ? 530 GLN B O   1 
ATOM   6475 C CB  . GLN B 2 541 ? 79.957  101.318 103.207 1.00 100.90 ? 530 GLN B CB  1 
ATOM   6476 C CG  . GLN B 2 541 ? 80.515  102.585 102.592 1.00 100.90 ? 530 GLN B CG  1 
ATOM   6477 C CD  . GLN B 2 541 ? 81.872  102.953 103.153 1.00 100.90 ? 530 GLN B CD  1 
ATOM   6478 O OE1 . GLN B 2 541 ? 81.972  103.521 104.238 1.00 100.90 ? 530 GLN B OE1 1 
ATOM   6479 N NE2 . GLN B 2 541 ? 82.926  102.634 102.411 1.00 100.90 ? 530 GLN B NE2 1 
ATOM   6480 N N   . ARG B 2 542 ? 80.027  97.902  103.688 1.00 92.35  ? 531 ARG B N   1 
ATOM   6481 C CA  . ARG B 2 542 ? 79.581  96.847  104.587 1.00 92.35  ? 531 ARG B CA  1 
ATOM   6482 C C   . ARG B 2 542 ? 80.656  95.803  104.838 1.00 92.35  ? 531 ARG B C   1 
ATOM   6483 O O   . ARG B 2 542 ? 80.862  95.390  105.982 1.00 92.35  ? 531 ARG B O   1 
ATOM   6484 C CB  . ARG B 2 542 ? 78.339  96.163  104.022 1.00 92.35  ? 531 ARG B CB  1 
ATOM   6485 C CG  . ARG B 2 542 ? 77.929  94.941  104.801 1.00 92.35  ? 531 ARG B CG  1 
ATOM   6486 C CD  . ARG B 2 542 ? 76.920  95.300  105.856 1.00 92.35  ? 531 ARG B CD  1 
ATOM   6487 N NE  . ARG B 2 542 ? 76.144  94.139  106.256 1.00 92.35  ? 531 ARG B NE  1 
ATOM   6488 C CZ  . ARG B 2 542 ? 76.520  93.300  107.210 1.00 92.35  ? 531 ARG B CZ  1 
ATOM   6489 N NH1 . ARG B 2 542 ? 77.658  93.501  107.855 1.00 92.35  ? 531 ARG B NH1 1 
ATOM   6490 N NH2 . ARG B 2 542 ? 75.761  92.263  107.518 1.00 92.35  ? 531 ARG B NH2 1 
ATOM   6491 N N   . SER B 2 543 ? 81.352  95.368  103.794 1.00 92.38  ? 532 SER B N   1 
ATOM   6492 C CA  . SER B 2 543 ? 82.319  94.289  103.908 1.00 92.38  ? 532 SER B CA  1 
ATOM   6493 C C   . SER B 2 543 ? 83.714  94.779  104.261 1.00 92.38  ? 532 SER B C   1 
ATOM   6494 O O   . SER B 2 543 ? 84.667  93.999  104.193 1.00 92.38  ? 532 SER B O   1 
ATOM   6495 C CB  . SER B 2 543 ? 82.365  93.488  102.608 1.00 92.38  ? 532 SER B CB  1 
ATOM   6496 O OG  . SER B 2 543 ? 83.583  92.777  102.498 1.00 92.38  ? 532 SER B OG  1 
ATOM   6497 N N   . LYS B 2 544 ? 83.863  96.049  104.630 1.00 94.20  ? 533 LYS B N   1 
ATOM   6498 C CA  . LYS B 2 544 ? 85.157  96.563  105.060 1.00 94.20  ? 533 LYS B CA  1 
ATOM   6499 C C   . LYS B 2 544 ? 85.108  97.410  106.321 1.00 94.20  ? 533 LYS B C   1 
ATOM   6500 O O   . LYS B 2 544 ? 86.148  97.557  106.973 1.00 94.20  ? 533 LYS B O   1 
ATOM   6501 C CB  . LYS B 2 544 ? 85.816  97.384  103.942 1.00 94.20  ? 533 LYS B CB  1 
ATOM   6502 C CG  . LYS B 2 544 ? 85.440  98.855  103.935 1.00 94.20  ? 533 LYS B CG  1 
ATOM   6503 C CD  . LYS B 2 544 ? 86.264  99.628  102.921 1.00 94.20  ? 533 LYS B CD  1 
ATOM   6504 C CE  . LYS B 2 544 ? 85.814  101.075 102.841 1.00 94.20  ? 533 LYS B CE  1 
ATOM   6505 N NZ  . LYS B 2 544 ? 85.966  101.774 104.146 1.00 94.20  ? 533 LYS B NZ  1 
ATOM   6506 N N   . GLU B 2 545 ? 83.960  97.970  106.690 1.00 95.68  ? 534 GLU B N   1 
ATOM   6507 C CA  . GLU B 2 545 ? 83.861  98.857  107.840 1.00 95.68  ? 534 GLU B CA  1 
ATOM   6508 C C   . GLU B 2 545 ? 83.424  98.064  109.065 1.00 95.68  ? 534 GLU B C   1 
ATOM   6509 O O   . GLU B 2 545 ? 82.463  97.291  108.999 1.00 95.68  ? 534 GLU B O   1 
ATOM   6510 C CB  . GLU B 2 545 ? 82.887  100.000 107.569 1.00 95.68  ? 534 GLU B CB  1 
ATOM   6511 C CG  . GLU B 2 545 ? 82.818  100.989 108.706 1.00 95.68  ? 534 GLU B CG  1 
ATOM   6512 C CD  . GLU B 2 545 ? 84.111  101.757 108.880 1.00 95.68  ? 534 GLU B CD  1 
ATOM   6513 O OE1 . GLU B 2 545 ? 84.864  101.891 107.893 1.00 95.68  ? 534 GLU B OE1 1 
ATOM   6514 O OE2 . GLU B 2 545 ? 84.382  102.218 110.007 1.00 95.68  ? 534 GLU B OE2 1 
ATOM   6515 N N   . ARG B 2 546 ? 84.137  98.257  110.177 1.00 92.07  ? 535 ARG B N   1 
ATOM   6516 C CA  . ARG B 2 546 ? 83.847  97.506  111.394 1.00 92.07  ? 535 ARG B CA  1 
ATOM   6517 C C   . ARG B 2 546 ? 82.429  97.760  111.886 1.00 92.07  ? 535 ARG B C   1 
ATOM   6518 O O   . ARG B 2 546 ? 81.607  96.839  111.942 1.00 92.07  ? 535 ARG B O   1 
ATOM   6519 C CB  . ARG B 2 546 ? 84.860  97.860  112.481 1.00 92.07  ? 535 ARG B CB  1 
ATOM   6520 C CG  . ARG B 2 546 ? 86.124  97.029  112.431 1.00 92.07  ? 535 ARG B CG  1 
ATOM   6521 C CD  . ARG B 2 546 ? 85.911  95.677  113.085 1.00 92.07  ? 535 ARG B CD  1 
ATOM   6522 N NE  . ARG B 2 546 ? 86.946  94.721  112.708 1.00 92.07  ? 535 ARG B NE  1 
ATOM   6523 C CZ  . ARG B 2 546 ? 88.167  94.692  113.233 1.00 92.07  ? 535 ARG B CZ  1 
ATOM   6524 N NH1 . ARG B 2 546 ? 89.041  93.784  112.827 1.00 92.07  ? 535 ARG B NH1 1 
ATOM   6525 N NH2 . ARG B 2 546 ? 88.514  95.571  114.162 1.00 92.07  ? 535 ARG B NH2 1 
ATOM   6526 N N   . SER B 2 547 ? 82.119  99.011  112.233 1.00 92.44  ? 536 SER B N   1 
ATOM   6527 C CA  . SER B 2 547 ? 80.890  99.321  112.956 1.00 92.44  ? 536 SER B CA  1 
ATOM   6528 C C   . SER B 2 547 ? 79.631  98.884  112.224 1.00 92.44  ? 536 SER B C   1 
ATOM   6529 O O   . SER B 2 547 ? 78.559  98.872  112.836 1.00 92.44  ? 536 SER B O   1 
ATOM   6530 C CB  . SER B 2 547 ? 80.809  100.815 113.244 1.00 92.44  ? 536 SER B CB  1 
ATOM   6531 O OG  . SER B 2 547 ? 79.487  101.179 113.588 1.00 92.44  ? 536 SER B OG  1 
ATOM   6532 N N   . LEU B 2 548 ? 79.722  98.537  110.944 1.00 92.97  ? 537 LEU B N   1 
ATOM   6533 C CA  . LEU B 2 548 ? 78.605  97.925  110.240 1.00 92.97  ? 537 LEU B CA  1 
ATOM   6534 C C   . LEU B 2 548 ? 78.652  96.409  110.268 1.00 92.97  ? 537 LEU B C   1 
ATOM   6535 O O   . LEU B 2 548 ? 77.598  95.769  110.306 1.00 92.97  ? 537 LEU B O   1 
ATOM   6536 C CB  . LEU B 2 548 ? 78.565  98.392  108.783 1.00 92.97  ? 537 LEU B CB  1 
ATOM   6537 C CG  . LEU B 2 548 ? 77.842  99.705  108.509 1.00 92.97  ? 537 LEU B CG  1 
ATOM   6538 C CD1 . LEU B 2 548 ? 77.706  99.917  107.015 1.00 92.97  ? 537 LEU B CD1 1 
ATOM   6539 C CD2 . LEU B 2 548 ? 76.485  99.703  109.182 1.00 92.97  ? 537 LEU B CD2 1 
ATOM   6540 N N   . LEU B 2 549 ? 79.854  95.829  110.240 1.00 89.87  ? 538 LEU B N   1 
ATOM   6541 C CA  . LEU B 2 549 ? 79.990  94.379  110.189 1.00 89.87  ? 538 LEU B CA  1 
ATOM   6542 C C   . LEU B 2 549 ? 79.328  93.719  111.392 1.00 89.87  ? 538 LEU B C   1 
ATOM   6543 O O   . LEU B 2 549 ? 78.537  92.781  111.244 1.00 89.87  ? 538 LEU B O   1 
ATOM   6544 C CB  . LEU B 2 549 ? 81.468  94.006  110.121 1.00 89.87  ? 538 LEU B CB  1 
ATOM   6545 C CG  . LEU B 2 549 ? 82.010  93.798  108.713 1.00 89.87  ? 538 LEU B CG  1 
ATOM   6546 C CD1 . LEU B 2 549 ? 83.462  93.361  108.745 1.00 89.87  ? 538 LEU B CD1 1 
ATOM   6547 C CD2 . LEU B 2 549 ? 81.153  92.790  108.001 1.00 89.87  ? 538 LEU B CD2 1 
ATOM   6548 N N   . HIS B 2 550 ? 79.643  94.196  112.595 1.00 85.09  ? 539 HIS B N   1 
ATOM   6549 C CA  . HIS B 2 550 ? 79.072  93.629  113.808 1.00 85.09  ? 539 HIS B CA  1 
ATOM   6550 C C   . HIS B 2 550 ? 78.681  94.693  114.825 1.00 85.09  ? 539 HIS B C   1 
ATOM   6551 O O   . HIS B 2 550 ? 78.418  94.349  115.983 1.00 85.09  ? 539 HIS B O   1 
ATOM   6552 C CB  . HIS B 2 550 ? 80.054  92.648  114.446 1.00 85.09  ? 539 HIS B CB  1 
ATOM   6553 C CG  . HIS B 2 550 ? 81.473  93.120  114.423 1.00 85.09  ? 539 HIS B CG  1 
ATOM   6554 N ND1 . HIS B 2 550 ? 81.959  94.058  115.309 1.00 85.09  ? 539 HIS B ND1 1 
ATOM   6555 C CD2 . HIS B 2 550 ? 82.510  92.786  113.619 1.00 85.09  ? 539 HIS B CD2 1 
ATOM   6556 C CE1 . HIS B 2 550 ? 83.233  94.284  115.051 1.00 85.09  ? 539 HIS B CE1 1 
ATOM   6557 N NE2 . HIS B 2 550 ? 83.592  93.523  114.031 1.00 85.09  ? 539 HIS B NE2 1 
ATOM   6558 N N   . GLY B 2 551 ? 78.636  95.963  114.439 1.00 84.57  ? 540 GLY B N   1 
ATOM   6559 C CA  . GLY B 2 551 ? 78.362  97.012  115.394 1.00 84.57  ? 540 GLY B CA  1 
ATOM   6560 C C   . GLY B 2 551 ? 76.962  96.928  115.964 1.00 84.57  ? 540 GLY B C   1 
ATOM   6561 O O   . GLY B 2 551 ? 76.058  96.315  115.401 1.00 84.57  ? 540 GLY B O   1 
ATOM   6562 N N   . ASP B 2 552 ? 76.791  97.560  117.119 1.00 89.86  ? 541 ASP B N   1 
ATOM   6563 C CA  . ASP B 2 552 ? 75.485  97.591  117.753 1.00 89.86  ? 541 ASP B CA  1 
ATOM   6564 C C   . ASP B 2 552 ? 74.537  98.490  116.973 1.00 89.86  ? 541 ASP B C   1 
ATOM   6565 O O   . ASP B 2 552 ? 74.958  99.394  116.242 1.00 89.86  ? 541 ASP B O   1 
ATOM   6566 C CB  . ASP B 2 552 ? 75.596  98.073  119.199 1.00 89.86  ? 541 ASP B CB  1 
ATOM   6567 C CG  . ASP B 2 552 ? 76.263  97.055  120.105 1.00 89.86  ? 541 ASP B CG  1 
ATOM   6568 O OD1 . ASP B 2 552 ? 75.838  95.881  120.096 1.00 89.86  ? 541 ASP B OD1 1 
ATOM   6569 O OD2 . ASP B 2 552 ? 77.207  97.429  120.832 1.00 89.86  ? 541 ASP B OD2 1 
ATOM   6570 N N   . PHE B 2 553 ? 73.244  98.254  117.177 1.00 95.89  ? 542 PHE B N   1 
ATOM   6571 C CA  . PHE B 2 553 ? 72.161  98.852  116.411 1.00 95.89  ? 542 PHE B CA  1 
ATOM   6572 C C   . PHE B 2 553 ? 71.162  99.480  117.366 1.00 95.89  ? 542 PHE B C   1 
ATOM   6573 O O   . PHE B 2 553 ? 70.604  98.783  118.219 1.00 95.89  ? 542 PHE B O   1 
ATOM   6574 C CB  . PHE B 2 553 ? 71.470  97.779  115.570 1.00 95.89  ? 542 PHE B CB  1 
ATOM   6575 C CG  . PHE B 2 553 ? 70.219  98.241  114.890 1.00 95.89  ? 542 PHE B CG  1 
ATOM   6576 C CD1 . PHE B 2 553 ? 70.268  98.948  113.707 1.00 95.89  ? 542 PHE B CD1 1 
ATOM   6577 C CD2 . PHE B 2 553 ? 68.986  97.954  115.441 1.00 95.89  ? 542 PHE B CD2 1 
ATOM   6578 C CE1 . PHE B 2 553 ? 69.105  99.355  113.088 1.00 95.89  ? 542 PHE B CE1 1 
ATOM   6579 C CE2 . PHE B 2 553 ? 67.823  98.360  114.828 1.00 95.89  ? 542 PHE B CE2 1 
ATOM   6580 C CZ  . PHE B 2 553 ? 67.884  99.060  113.651 1.00 95.89  ? 542 PHE B CZ  1 
ATOM   6581 N N   . HIS B 2 554 ? 70.920  100.781 117.223 1.00 105.09 ? 543 HIS B N   1 
ATOM   6582 C CA  . HIS B 2 554 ? 69.983  101.463 118.112 1.00 105.09 ? 543 HIS B CA  1 
ATOM   6583 C C   . HIS B 2 554 ? 69.179  102.485 117.328 1.00 105.09 ? 543 HIS B C   1 
ATOM   6584 O O   . HIS B 2 554 ? 69.753  103.400 116.736 1.00 105.09 ? 543 HIS B O   1 
ATOM   6585 C CB  . HIS B 2 554 ? 70.720  102.132 119.273 1.00 105.09 ? 543 HIS B CB  1 
ATOM   6586 C CG  . HIS B 2 554 ? 71.114  101.182 120.359 1.00 105.09 ? 543 HIS B CG  1 
ATOM   6587 N ND1 . HIS B 2 554 ? 72.424  100.829 120.599 1.00 105.09 ? 543 HIS B ND1 1 
ATOM   6588 C CD2 . HIS B 2 554 ? 70.370  100.503 121.263 1.00 105.09 ? 543 HIS B CD2 1 
ATOM   6589 C CE1 . HIS B 2 554 ? 72.471  99.975  121.605 1.00 105.09 ? 543 HIS B CE1 1 
ATOM   6590 N NE2 . HIS B 2 554 ? 71.237  99.761  122.027 1.00 105.09 ? 543 HIS B NE2 1 
ATOM   6591 N N   . ALA B 2 555 ? 67.860  102.338 117.327 1.00 118.51 ? 544 ALA B N   1 
ATOM   6592 C CA  . ALA B 2 555 ? 66.983  103.238 116.595 1.00 118.51 ? 544 ALA B CA  1 
ATOM   6593 C C   . ALA B 2 555 ? 66.351  104.254 117.537 1.00 118.51 ? 544 ALA B C   1 
ATOM   6594 O O   . ALA B 2 555 ? 65.978  103.932 118.668 1.00 118.51 ? 544 ALA B O   1 
ATOM   6595 C CB  . ALA B 2 555 ? 65.889  102.460 115.864 1.00 118.51 ? 544 ALA B CB  1 
ATOM   6596 N N   . PHE B 2 556 ? 66.235  105.491 117.060 1.00 132.04 ? 545 PHE B N   1 
ATOM   6597 C CA  . PHE B 2 556 ? 65.557  106.545 117.797 1.00 132.04 ? 545 PHE B CA  1 
ATOM   6598 C C   . PHE B 2 556 ? 64.422  107.103 116.951 1.00 132.04 ? 545 PHE B C   1 
ATOM   6599 O O   . PHE B 2 556 ? 64.450  107.046 115.719 1.00 132.04 ? 545 PHE B O   1 
ATOM   6600 C CB  . PHE B 2 556 ? 66.522  107.667 118.220 1.00 132.04 ? 545 PHE B CB  1 
ATOM   6601 C CG  . PHE B 2 556 ? 67.353  108.231 117.097 1.00 132.04 ? 545 PHE B CG  1 
ATOM   6602 C CD1 . PHE B 2 556 ? 66.821  109.150 116.211 1.00 132.04 ? 545 PHE B CD1 1 
ATOM   6603 C CD2 . PHE B 2 556 ? 68.675  107.852 116.941 1.00 132.04 ? 545 PHE B CD2 1 
ATOM   6604 C CE1 . PHE B 2 556 ? 67.588  109.671 115.187 1.00 132.04 ? 545 PHE B CE1 1 
ATOM   6605 C CE2 . PHE B 2 556 ? 69.445  108.370 115.920 1.00 132.04 ? 545 PHE B CE2 1 
ATOM   6606 C CZ  . PHE B 2 556 ? 68.901  109.279 115.042 1.00 132.04 ? 545 PHE B CZ  1 
ATOM   6607 N N   . SER B 2 557 ? 63.415  107.641 117.633 1.00 138.26 ? 546 SER B N   1 
ATOM   6608 C CA  . SER B 2 557 ? 62.218  108.115 116.959 1.00 138.26 ? 546 SER B CA  1 
ATOM   6609 C C   . SER B 2 557 ? 62.533  109.313 116.067 1.00 138.26 ? 546 SER B C   1 
ATOM   6610 O O   . SER B 2 557 ? 63.541  110.005 116.232 1.00 138.26 ? 546 SER B O   1 
ATOM   6611 C CB  . SER B 2 557 ? 61.142  108.489 117.976 1.00 138.26 ? 546 SER B CB  1 
ATOM   6612 O OG  . SER B 2 557 ? 60.120  109.262 117.372 1.00 138.26 ? 546 SER B OG  1 
ATOM   6613 N N   . ALA B 2 558 ? 61.646  109.549 115.108 1.00 142.20 ? 547 ALA B N   1 
ATOM   6614 C CA  . ALA B 2 558 ? 61.801  110.629 114.142 1.00 142.20 ? 547 ALA B CA  1 
ATOM   6615 C C   . ALA B 2 558 ? 60.408  111.092 113.728 1.00 142.20 ? 547 ALA B C   1 
ATOM   6616 O O   . ALA B 2 558 ? 59.418  110.804 114.408 1.00 142.20 ? 547 ALA B O   1 
ATOM   6617 C CB  . ALA B 2 558 ? 62.663  110.170 112.954 1.00 142.20 ? 547 ALA B CB  1 
ATOM   6618 N N   . GLY B 2 559 ? 60.331  111.816 112.613 1.00 145.19 ? 548 GLY B N   1 
ATOM   6619 C CA  . GLY B 2 559 ? 59.078  112.330 112.113 1.00 145.19 ? 548 GLY B CA  1 
ATOM   6620 C C   . GLY B 2 559 ? 58.080  111.244 111.761 1.00 145.19 ? 548 GLY B C   1 
ATOM   6621 O O   . GLY B 2 559 ? 58.373  110.046 111.827 1.00 145.19 ? 548 GLY B O   1 
ATOM   6622 N N   . PRO B 2 560 ? 56.872  111.650 111.368 1.00 143.98 ? 549 PRO B N   1 
ATOM   6623 C CA  . PRO B 2 560 ? 55.784  110.688 111.080 1.00 143.98 ? 549 PRO B CA  1 
ATOM   6624 C C   . PRO B 2 560 ? 55.944  109.960 109.746 1.00 143.98 ? 549 PRO B C   1 
ATOM   6625 O O   . PRO B 2 560 ? 55.390  110.325 108.709 1.00 143.98 ? 549 PRO B O   1 
ATOM   6626 C CB  . PRO B 2 560 ? 54.539  111.578 111.098 1.00 143.98 ? 549 PRO B CB  1 
ATOM   6627 C CG  . PRO B 2 560 ? 55.036  112.915 110.668 1.00 143.98 ? 549 PRO B CG  1 
ATOM   6628 C CD  . PRO B 2 560 ? 56.433  113.048 111.214 1.00 143.98 ? 549 PRO B CD  1 
ATOM   6629 N N   . GLY B 2 561 ? 56.731  108.888 109.769 1.00 139.12 ? 550 GLY B N   1 
ATOM   6630 C CA  . GLY B 2 561 ? 56.918  108.071 108.586 1.00 139.12 ? 550 GLY B CA  1 
ATOM   6631 C C   . GLY B 2 561 ? 58.370  107.873 108.208 1.00 139.12 ? 550 GLY B C   1 
ATOM   6632 O O   . GLY B 2 561 ? 58.673  107.402 107.107 1.00 139.12 ? 550 GLY B O   1 
ATOM   6633 N N   . LEU B 2 562 ? 59.278  108.227 109.108 1.00 135.05 ? 551 LEU B N   1 
ATOM   6634 C CA  . LEU B 2 562 ? 60.705  108.075 108.874 1.00 135.05 ? 551 LEU B CA  1 
ATOM   6635 C C   . LEU B 2 562 ? 61.206  106.776 109.494 1.00 135.05 ? 551 LEU B C   1 
ATOM   6636 O O   . LEU B 2 562 ? 60.483  106.067 110.196 1.00 135.05 ? 551 LEU B O   1 
ATOM   6637 C CB  . LEU B 2 562 ? 61.480  109.265 109.450 1.00 135.05 ? 551 LEU B CB  1 
ATOM   6638 C CG  . LEU B 2 562 ? 61.598  110.557 108.635 1.00 135.05 ? 551 LEU B CG  1 
ATOM   6639 C CD1 . LEU B 2 562 ? 62.318  110.311 107.319 1.00 135.05 ? 551 LEU B CD1 1 
ATOM   6640 C CD2 . LEU B 2 562 ? 60.241  111.202 108.405 1.00 135.05 ? 551 LEU B CD2 1 
ATOM   6641 N N   . PHE B 2 563 ? 62.471  106.468 109.219 1.00 124.43 ? 552 PHE B N   1 
ATOM   6642 C CA  . PHE B 2 563 ? 63.154  105.358 109.877 1.00 124.43 ? 552 PHE B CA  1 
ATOM   6643 C C   . PHE B 2 563 ? 64.585  105.774 110.167 1.00 124.43 ? 552 PHE B C   1 
ATOM   6644 O O   . PHE B 2 563 ? 65.360  106.007 109.240 1.00 124.43 ? 552 PHE B O   1 
ATOM   6645 C CB  . PHE B 2 563 ? 63.121  104.094 109.014 1.00 124.43 ? 552 PHE B CB  1 
ATOM   6646 C CG  . PHE B 2 563 ? 63.577  102.860 109.733 1.00 124.43 ? 552 PHE B CG  1 
ATOM   6647 C CD1 . PHE B 2 563 ? 62.945  102.440 110.886 1.00 124.43 ? 552 PHE B CD1 1 
ATOM   6648 C CD2 . PHE B 2 563 ? 64.629  102.112 109.246 1.00 124.43 ? 552 PHE B CD2 1 
ATOM   6649 C CE1 . PHE B 2 563 ? 63.365  101.308 111.545 1.00 124.43 ? 552 PHE B CE1 1 
ATOM   6650 C CE2 . PHE B 2 563 ? 65.043  100.976 109.899 1.00 124.43 ? 552 PHE B CE2 1 
ATOM   6651 C CZ  . PHE B 2 563 ? 64.413  100.576 111.050 1.00 124.43 ? 552 PHE B CZ  1 
ATOM   6652 N N   . SER B 2 564 ? 64.946  105.846 111.444 1.00 124.14 ? 553 SER B N   1 
ATOM   6653 C CA  . SER B 2 564 ? 66.220  106.422 111.855 1.00 124.14 ? 553 SER B CA  1 
ATOM   6654 C C   . SER B 2 564 ? 66.889  105.519 112.878 1.00 124.14 ? 553 SER B C   1 
ATOM   6655 O O   . SER B 2 564 ? 66.265  105.132 113.871 1.00 124.14 ? 553 SER B O   1 
ATOM   6656 C CB  . SER B 2 564 ? 66.016  107.824 112.430 1.00 124.14 ? 553 SER B CB  1 
ATOM   6657 O OG  . SER B 2 564 ? 65.634  107.754 113.791 1.00 124.14 ? 553 SER B OG  1 
ATOM   6658 N N   . TYR B 2 565 ? 68.156  105.189 112.637 1.00 108.43 ? 554 TYR B N   1 
ATOM   6659 C CA  . TYR B 2 565 ? 68.912  104.378 113.579 1.00 108.43 ? 554 TYR B CA  1 
ATOM   6660 C C   . TYR B 2 565 ? 70.394  104.704 113.469 1.00 108.43 ? 554 TYR B C   1 
ATOM   6661 O O   . TYR B 2 565 ? 70.827  105.461 112.597 1.00 108.43 ? 554 TYR B O   1 
ATOM   6662 C CB  . TYR B 2 565 ? 68.665  102.882 113.357 1.00 108.43 ? 554 TYR B CB  1 
ATOM   6663 C CG  . TYR B 2 565 ? 68.976  102.384 111.965 1.00 108.43 ? 554 TYR B CG  1 
ATOM   6664 C CD1 . TYR B 2 565 ? 70.278  102.097 111.581 1.00 108.43 ? 554 TYR B CD1 1 
ATOM   6665 C CD2 . TYR B 2 565 ? 67.965  102.167 111.049 1.00 108.43 ? 554 TYR B CD2 1 
ATOM   6666 C CE1 . TYR B 2 565 ? 70.558  101.634 110.316 1.00 108.43 ? 554 TYR B CE1 1 
ATOM   6667 C CE2 . TYR B 2 565 ? 68.237  101.705 109.784 1.00 108.43 ? 554 TYR B CE2 1 
ATOM   6668 C CZ  . TYR B 2 565 ? 69.532  101.440 109.423 1.00 108.43 ? 554 TYR B CZ  1 
ATOM   6669 O OH  . TYR B 2 565 ? 69.796  100.978 108.157 1.00 108.43 ? 554 TYR B OH  1 
ATOM   6670 N N   . ILE B 2 566 ? 71.169  104.105 114.371 1.00 103.90 ? 555 ILE B N   1 
ATOM   6671 C CA  . ILE B 2 566 ? 72.606  104.311 114.465 1.00 103.90 ? 555 ILE B CA  1 
ATOM   6672 C C   . ILE B 2 566 ? 73.284  102.954 114.590 1.00 103.90 ? 555 ILE B C   1 
ATOM   6673 O O   . ILE B 2 566 ? 72.769  102.043 115.253 1.00 103.90 ? 555 ILE B O   1 
ATOM   6674 C CB  . ILE B 2 566 ? 72.972  105.224 115.657 1.00 103.90 ? 555 ILE B CB  1 
ATOM   6675 C CG1 . ILE B 2 566 ? 74.461  105.562 115.652 1.00 103.90 ? 555 ILE B CG1 1 
ATOM   6676 C CG2 . ILE B 2 566 ? 72.609  104.574 116.973 1.00 103.90 ? 555 ILE B CG2 1 
ATOM   6677 C CD1 . ILE B 2 566 ? 74.839  106.646 116.637 1.00 103.90 ? 555 ILE B CD1 1 
ATOM   6678 N N   . ARG B 2 567 ? 74.433  102.821 113.929 1.00 93.90  ? 556 ARG B N   1 
ATOM   6679 C CA  . ARG B 2 567 ? 75.271  101.630 113.967 1.00 93.90  ? 556 ARG B CA  1 
ATOM   6680 C C   . ARG B 2 567 ? 76.632  102.026 114.522 1.00 93.90  ? 556 ARG B C   1 
ATOM   6681 O O   . ARG B 2 567 ? 77.365  102.793 113.886 1.00 93.90  ? 556 ARG B O   1 
ATOM   6682 C CB  . ARG B 2 567 ? 75.415  101.019 112.573 1.00 93.90  ? 556 ARG B CB  1 
ATOM   6683 C CG  . ARG B 2 567 ? 74.119  100.522 111.973 1.00 93.90  ? 556 ARG B CG  1 
ATOM   6684 C CD  . ARG B 2 567 ? 73.702  99.211  112.603 1.00 93.90  ? 556 ARG B CD  1 
ATOM   6685 N NE  . ARG B 2 567 ? 74.795  98.244  112.597 1.00 93.90  ? 556 ARG B NE  1 
ATOM   6686 C CZ  . ARG B 2 567 ? 74.836  97.164  111.826 1.00 93.90  ? 556 ARG B CZ  1 
ATOM   6687 N NH1 . ARG B 2 567 ? 73.845  96.909  110.991 1.00 93.90  ? 556 ARG B NH1 1 
ATOM   6688 N NH2 . ARG B 2 567 ? 75.872  96.340  111.887 1.00 93.90  ? 556 ARG B NH2 1 
ATOM   6689 N N   . HIS B 2 568 ? 76.962  101.515 115.708 1.00 94.04  ? 557 HIS B N   1 
ATOM   6690 C CA  . HIS B 2 568 ? 78.196  101.894 116.394 1.00 94.04  ? 557 HIS B CA  1 
ATOM   6691 C C   . HIS B 2 568 ? 78.780  100.678 117.093 1.00 94.04  ? 557 HIS B C   1 
ATOM   6692 O O   . HIS B 2 568 ? 78.088  100.037 117.889 1.00 94.04  ? 557 HIS B O   1 
ATOM   6693 C CB  . HIS B 2 568 ? 77.935  103.016 117.403 1.00 94.04  ? 557 HIS B CB  1 
ATOM   6694 C CG  . HIS B 2 568 ? 76.806  102.735 118.344 1.00 94.04  ? 557 HIS B CG  1 
ATOM   6695 N ND1 . HIS B 2 568 ? 76.742  101.595 119.115 1.00 94.04  ? 557 HIS B ND1 1 
ATOM   6696 C CD2 . HIS B 2 568 ? 75.694  103.449 118.637 1.00 94.04  ? 557 HIS B CD2 1 
ATOM   6697 C CE1 . HIS B 2 568 ? 75.641  101.618 119.843 1.00 94.04  ? 557 HIS B CE1 1 
ATOM   6698 N NE2 . HIS B 2 568 ? 74.987  102.733 119.572 1.00 94.04  ? 557 HIS B NE2 1 
ATOM   6699 N N   . TRP B 2 569 ? 80.045  100.355 116.807 1.00 90.05  ? 558 TRP B N   1 
ATOM   6700 C CA  . TRP B 2 569 ? 80.615  99.167  117.431 1.00 90.05  ? 558 TRP B CA  1 
ATOM   6701 C C   . TRP B 2 569 ? 81.422  99.466  118.689 1.00 90.05  ? 558 TRP B C   1 
ATOM   6702 O O   . TRP B 2 569 ? 80.950  99.201  119.798 1.00 90.05  ? 558 TRP B O   1 
ATOM   6703 C CB  . TRP B 2 569 ? 81.501  98.435  116.420 1.00 90.05  ? 558 TRP B CB  1 
ATOM   6704 C CG  . TRP B 2 569 ? 82.426  97.418  117.011 1.00 90.05  ? 558 TRP B CG  1 
ATOM   6705 C CD1 . TRP B 2 569 ? 83.755  97.290  116.755 1.00 90.05  ? 558 TRP B CD1 1 
ATOM   6706 C CD2 . TRP B 2 569 ? 82.093  96.376  117.934 1.00 90.05  ? 558 TRP B CD2 1 
ATOM   6707 N NE1 . TRP B 2 569 ? 84.275  96.242  117.468 1.00 90.05  ? 558 TRP B NE1 1 
ATOM   6708 C CE2 . TRP B 2 569 ? 83.273  95.664  118.199 1.00 90.05  ? 558 TRP B CE2 1 
ATOM   6709 C CE3 . TRP B 2 569 ? 80.912  95.980  118.565 1.00 90.05  ? 558 TRP B CE3 1 
ATOM   6710 C CZ2 . TRP B 2 569 ? 83.309  94.582  119.067 1.00 90.05  ? 558 TRP B CZ2 1 
ATOM   6711 C CZ3 . TRP B 2 569 ? 80.950  94.905  119.423 1.00 90.05  ? 558 TRP B CZ3 1 
ATOM   6712 C CH2 . TRP B 2 569 ? 82.138  94.218  119.669 1.00 90.05  ? 558 TRP B CH2 1 
ATOM   6713 N N   . ASP B 2 570 ? 82.625  100.024 118.545 1.00 98.04  ? 559 ASP B N   1 
ATOM   6714 C CA  . ASP B 2 570 ? 83.347  100.514 119.714 1.00 98.04  ? 559 ASP B CA  1 
ATOM   6715 C C   . ASP B 2 570 ? 83.842  101.938 119.526 1.00 98.04  ? 559 ASP B C   1 
ATOM   6716 O O   . ASP B 2 570 ? 83.422  102.861 120.231 1.00 98.04  ? 559 ASP B O   1 
ATOM   6717 C CB  . ASP B 2 570 ? 84.536  99.604  120.021 1.00 98.04  ? 559 ASP B CB  1 
ATOM   6718 C CG  . ASP B 2 570 ? 84.884  99.578  121.491 1.00 98.04  ? 559 ASP B CG  1 
ATOM   6719 O OD1 . ASP B 2 570 ? 84.074  100.070 122.303 1.00 98.04  ? 559 ASP B OD1 1 
ATOM   6720 O OD2 . ASP B 2 570 ? 85.974  99.079  121.835 1.00 98.04  ? 559 ASP B OD2 1 
ATOM   6721 N N   . GLN B 2 571 ? 84.729  102.112 118.548 1.00 101.29 ? 560 GLN B N   1 
ATOM   6722 C CA  . GLN B 2 571 ? 85.321  103.404 118.244 1.00 101.29 ? 560 GLN B CA  1 
ATOM   6723 C C   . GLN B 2 571 ? 85.540  103.609 116.755 1.00 101.29 ? 560 GLN B C   1 
ATOM   6724 O O   . GLN B 2 571 ? 86.078  104.650 116.369 1.00 101.29 ? 560 GLN B O   1 
ATOM   6725 C CB  . GLN B 2 571 ? 86.662  103.579 118.978 1.00 101.29 ? 560 GLN B CB  1 
ATOM   6726 C CG  . GLN B 2 571 ? 86.542  103.750 120.483 1.00 101.29 ? 560 GLN B CG  1 
ATOM   6727 C CD  . GLN B 2 571 ? 87.878  104.005 121.151 1.00 101.29 ? 560 GLN B CD  1 
ATOM   6728 O OE1 . GLN B 2 571 ? 88.623  104.896 120.747 1.00 101.29 ? 560 GLN B OE1 1 
ATOM   6729 N NE2 . GLN B 2 571 ? 88.187  103.223 122.178 1.00 101.29 ? 560 GLN B NE2 1 
ATOM   6730 N N   . ASN B 2 572 ? 85.155  102.655 115.914 1.00 100.64 ? 561 ASN B N   1 
ATOM   6731 C CA  . ASN B 2 572 ? 85.271  102.844 114.482 1.00 100.64 ? 561 ASN B CA  1 
ATOM   6732 C C   . ASN B 2 572 ? 84.212  103.830 114.003 1.00 100.64 ? 561 ASN B C   1 
ATOM   6733 O O   . ASN B 2 572 ? 83.390  104.328 114.779 1.00 100.64 ? 561 ASN B O   1 
ATOM   6734 C CB  . ASN B 2 572 ? 85.148  101.509 113.752 1.00 100.64 ? 561 ASN B CB  1 
ATOM   6735 C CG  . ASN B 2 572 ? 86.320  100.588 114.024 1.00 100.64 ? 561 ASN B CG  1 
ATOM   6736 O OD1 . ASN B 2 572 ? 87.279  100.543 113.255 1.00 100.64 ? 561 ASN B OD1 1 
ATOM   6737 N ND2 . ASN B 2 572 ? 86.249  99.846  115.121 1.00 100.64 ? 561 ASN B ND2 1 
ATOM   6738 N N   . GLU B 2 573 ? 84.251  104.124 112.708 1.00 107.31 ? 562 GLU B N   1 
ATOM   6739 C CA  . GLU B 2 573 ? 83.369  105.134 112.142 1.00 107.31 ? 562 GLU B CA  1 
ATOM   6740 C C   . GLU B 2 573 ? 81.922  104.800 112.472 1.00 107.31 ? 562 GLU B C   1 
ATOM   6741 O O   . GLU B 2 573 ? 81.403  103.763 112.052 1.00 107.31 ? 562 GLU B O   1 
ATOM   6742 C CB  . GLU B 2 573 ? 83.569  105.217 110.630 1.00 107.31 ? 562 GLU B CB  1 
ATOM   6743 C CG  . GLU B 2 573 ? 84.659  106.185 110.193 1.00 107.31 ? 562 GLU B CG  1 
ATOM   6744 C CD  . GLU B 2 573 ? 84.533  107.554 110.830 1.00 107.31 ? 562 GLU B CD  1 
ATOM   6745 O OE1 . GLU B 2 573 ? 83.432  108.139 110.788 1.00 107.31 ? 562 GLU B OE1 1 
ATOM   6746 O OE2 . GLU B 2 573 ? 85.542  108.046 111.377 1.00 107.31 ? 562 GLU B OE2 1 
ATOM   6747 N N   . ARG B 2 574 ? 81.282  105.667 113.248 1.00 109.39 ? 563 ARG B N   1 
ATOM   6748 C CA  . ARG B 2 574 ? 79.902  105.456 113.655 1.00 109.39 ? 563 ARG B CA  1 
ATOM   6749 C C   . ARG B 2 574 ? 78.946  105.960 112.582 1.00 109.39 ? 563 ARG B C   1 
ATOM   6750 O O   . ARG B 2 574 ? 79.038  107.110 112.136 1.00 109.39 ? 563 ARG B O   1 
ATOM   6751 C CB  . ARG B 2 574 ? 79.631  106.166 114.978 1.00 109.39 ? 563 ARG B CB  1 
ATOM   6752 C CG  . ARG B 2 574 ? 80.250  105.488 116.182 1.00 109.39 ? 563 ARG B CG  1 
ATOM   6753 C CD  . ARG B 2 574 ? 80.428  106.468 117.329 1.00 109.39 ? 563 ARG B CD  1 
ATOM   6754 N NE  . ARG B 2 574 ? 80.353  105.824 118.638 1.00 109.39 ? 563 ARG B NE  1 
ATOM   6755 C CZ  . ARG B 2 574 ? 81.268  104.992 119.123 1.00 109.39 ? 563 ARG B CZ  1 
ATOM   6756 N NH1 . ARG B 2 574 ? 82.343  104.690 118.410 1.00 109.39 ? 563 ARG B NH1 1 
ATOM   6757 N NH2 . ARG B 2 574 ? 81.107  104.460 120.326 1.00 109.39 ? 563 ARG B NH2 1 
ATOM   6758 N N   . PHE B 2 575 ? 78.021  105.096 112.171 1.00 103.69 ? 564 PHE B N   1 
ATOM   6759 C CA  . PHE B 2 575 ? 77.105  105.392 111.082 1.00 103.69 ? 564 PHE B CA  1 
ATOM   6760 C C   . PHE B 2 575 ? 75.728  105.735 111.628 1.00 103.69 ? 564 PHE B C   1 
ATOM   6761 O O   . PHE B 2 575 ? 75.316  105.234 112.673 1.00 103.69 ? 564 PHE B O   1 
ATOM   6762 C CB  . PHE B 2 575 ? 76.983  104.203 110.126 1.00 103.69 ? 564 PHE B CB  1 
ATOM   6763 C CG  . PHE B 2 575 ? 78.180  104.002 109.254 1.00 103.69 ? 564 PHE B CG  1 
ATOM   6764 C CD1 . PHE B 2 575 ? 79.389  103.623 109.797 1.00 103.69 ? 564 PHE B CD1 1 
ATOM   6765 C CD2 . PHE B 2 575 ? 78.095  104.189 107.889 1.00 103.69 ? 564 PHE B CD2 1 
ATOM   6766 C CE1 . PHE B 2 575 ? 80.492  103.439 109.000 1.00 103.69 ? 564 PHE B CE1 1 
ATOM   6767 C CE2 . PHE B 2 575 ? 79.198  104.003 107.085 1.00 103.69 ? 564 PHE B CE2 1 
ATOM   6768 C CZ  . PHE B 2 575 ? 80.398  103.626 107.643 1.00 103.69 ? 564 PHE B CZ  1 
ATOM   6769 N N   . LEU B 2 576 ? 75.012  106.584 110.899 1.00 113.80 ? 565 LEU B N   1 
ATOM   6770 C CA  . LEU B 2 576 ? 73.618  106.888 111.179 1.00 113.80 ? 565 LEU B CA  1 
ATOM   6771 C C   . LEU B 2 576 ? 72.857  106.783 109.871 1.00 113.80 ? 565 LEU B C   1 
ATOM   6772 O O   . LEU B 2 576 ? 73.325  107.270 108.839 1.00 113.80 ? 565 LEU B O   1 
ATOM   6773 C CB  . LEU B 2 576 ? 73.452  108.285 111.783 1.00 113.80 ? 565 LEU B CB  1 
ATOM   6774 C CG  . LEU B 2 576 ? 72.114  108.587 112.462 1.00 113.80 ? 565 LEU B CG  1 
ATOM   6775 C CD1 . LEU B 2 576 ? 72.307  109.611 113.562 1.00 113.80 ? 565 LEU B CD1 1 
ATOM   6776 C CD2 . LEU B 2 576 ? 71.075  109.078 111.465 1.00 113.80 ? 565 LEU B CD2 1 
ATOM   6777 N N   . VAL B 2 577 ? 71.694  106.150 109.909 1.00 114.90 ? 566 VAL B N   1 
ATOM   6778 C CA  . VAL B 2 577 ? 70.881  105.959 108.719 1.00 114.90 ? 566 VAL B CA  1 
ATOM   6779 C C   . VAL B 2 577 ? 69.501  106.534 108.985 1.00 114.90 ? 566 VAL B C   1 
ATOM   6780 O O   . VAL B 2 577 ? 68.971  106.413 110.097 1.00 114.90 ? 566 VAL B O   1 
ATOM   6781 C CB  . VAL B 2 577 ? 70.789  104.470 108.324 1.00 114.90 ? 566 VAL B CB  1 
ATOM   6782 C CG1 . VAL B 2 577 ? 69.897  104.285 107.108 1.00 114.90 ? 566 VAL B CG1 1 
ATOM   6783 C CG2 . VAL B 2 577 ? 72.169  103.906 108.065 1.00 114.90 ? 566 VAL B CG2 1 
ATOM   6784 N N   . VAL B 2 578 ? 68.928  107.170 107.969 1.00 125.76 ? 567 VAL B N   1 
ATOM   6785 C CA  . VAL B 2 578 ? 67.545  107.630 108.043 1.00 125.76 ? 567 VAL B CA  1 
ATOM   6786 C C   . VAL B 2 578 ? 66.904  107.504 106.667 1.00 125.76 ? 567 VAL B C   1 
ATOM   6787 O O   . VAL B 2 578 ? 67.538  107.757 105.637 1.00 125.76 ? 567 VAL B O   1 
ATOM   6788 C CB  . VAL B 2 578 ? 67.436  109.067 108.600 1.00 125.76 ? 567 VAL B CB  1 
ATOM   6789 C CG1 . VAL B 2 578 ? 67.899  110.093 107.591 1.00 125.76 ? 567 VAL B CG1 1 
ATOM   6790 C CG2 . VAL B 2 578 ? 66.010  109.357 109.046 1.00 125.76 ? 567 VAL B CG2 1 
ATOM   6791 N N   . LEU B 2 579 ? 65.640  107.101 106.659 1.00 129.62 ? 568 LEU B N   1 
ATOM   6792 C CA  . LEU B 2 579 ? 64.947  106.646 105.467 1.00 129.62 ? 568 LEU B CA  1 
ATOM   6793 C C   . LEU B 2 579 ? 63.569  107.284 105.409 1.00 129.62 ? 568 LEU B C   1 
ATOM   6794 O O   . LEU B 2 579 ? 62.831  107.273 106.401 1.00 129.62 ? 568 LEU B O   1 
ATOM   6795 C CB  . LEU B 2 579 ? 64.810  105.123 105.470 1.00 129.62 ? 568 LEU B CB  1 
ATOM   6796 C CG  . LEU B 2 579 ? 66.096  104.297 105.413 1.00 129.62 ? 568 LEU B CG  1 
ATOM   6797 C CD1 . LEU B 2 579 ? 65.774  102.855 105.076 1.00 129.62 ? 568 LEU B CD1 1 
ATOM   6798 C CD2 . LEU B 2 579 ? 67.087  104.875 104.421 1.00 129.62 ? 568 LEU B CD2 1 
ATOM   6799 N N   . ASN B 2 580 ? 63.228  107.823 104.238 1.00 135.79 ? 569 ASN B N   1 
ATOM   6800 C CA  . ASN B 2 580 ? 61.970  108.529 104.006 1.00 135.79 ? 569 ASN B CA  1 
ATOM   6801 C C   . ASN B 2 580 ? 60.987  107.549 103.377 1.00 135.79 ? 569 ASN B C   1 
ATOM   6802 O O   . ASN B 2 580 ? 61.017  107.315 102.166 1.00 135.79 ? 569 ASN B O   1 
ATOM   6803 C CB  . ASN B 2 580 ? 62.201  109.751 103.119 1.00 135.79 ? 569 ASN B CB  1 
ATOM   6804 C CG  . ASN B 2 580 ? 60.909  110.476 102.744 1.00 135.79 ? 569 ASN B CG  1 
ATOM   6805 O OD1 . ASN B 2 580 ? 59.984  109.893 102.179 1.00 135.79 ? 569 ASN B OD1 1 
ATOM   6806 N ND2 . ASN B 2 580 ? 60.852  111.764 103.057 1.00 135.79 ? 569 ASN B ND2 1 
ATOM   6807 N N   . PHE B 2 581 ? 60.110  106.982 104.198 1.00 133.84 ? 570 PHE B N   1 
ATOM   6808 C CA  . PHE B 2 581 ? 59.060  106.090 103.706 1.00 133.84 ? 570 PHE B CA  1 
ATOM   6809 C C   . PHE B 2 581 ? 57.776  106.857 103.407 1.00 133.84 ? 570 PHE B C   1 
ATOM   6810 O O   . PHE B 2 581 ? 56.698  106.514 103.887 1.00 133.84 ? 570 PHE B O   1 
ATOM   6811 C CB  . PHE B 2 581 ? 58.803  104.978 104.715 1.00 133.84 ? 570 PHE B CB  1 
ATOM   6812 C CG  . PHE B 2 581 ? 59.798  103.855 104.657 1.00 133.84 ? 570 PHE B CG  1 
ATOM   6813 C CD1 . PHE B 2 581 ? 61.153  104.098 104.794 1.00 133.84 ? 570 PHE B CD1 1 
ATOM   6814 C CD2 . PHE B 2 581 ? 59.372  102.550 104.481 1.00 133.84 ? 570 PHE B CD2 1 
ATOM   6815 C CE1 . PHE B 2 581 ? 62.063  103.064 104.745 1.00 133.84 ? 570 PHE B CE1 1 
ATOM   6816 C CE2 . PHE B 2 581 ? 60.278  101.512 104.430 1.00 133.84 ? 570 PHE B CE2 1 
ATOM   6817 C CZ  . PHE B 2 581 ? 61.625  101.769 104.564 1.00 133.84 ? 570 PHE B CZ  1 
ATOM   6818 N N   . GLY B 2 582 ? 57.887  107.909 102.601 1.00 138.06 ? 571 GLY B N   1 
ATOM   6819 C CA  . GLY B 2 582 ? 56.739  108.741 102.293 1.00 138.06 ? 571 GLY B CA  1 
ATOM   6820 C C   . GLY B 2 582 ? 56.831  109.301 100.891 1.00 138.06 ? 571 GLY B C   1 
ATOM   6821 O O   . GLY B 2 582 ? 57.898  109.313 100.269 1.00 138.06 ? 571 GLY B O   1 
ATOM   6822 N N   . ASP B 2 583 ? 55.685  109.768 100.395 1.00 144.49 ? 572 ASP B N   1 
ATOM   6823 C CA  . ASP B 2 583 ? 55.585  110.340 99.060  1.00 144.49 ? 572 ASP B CA  1 
ATOM   6824 C C   . ASP B 2 583 ? 55.548  111.864 99.079  1.00 144.49 ? 572 ASP B C   1 
ATOM   6825 O O   . ASP B 2 583 ? 55.211  112.482 98.063  1.00 144.49 ? 572 ASP B O   1 
ATOM   6826 C CB  . ASP B 2 583 ? 54.352  109.789 98.343  1.00 144.49 ? 572 ASP B CB  1 
ATOM   6827 C CG  . ASP B 2 583 ? 54.465  108.307 98.052  1.00 144.49 ? 572 ASP B CG  1 
ATOM   6828 O OD1 . ASP B 2 583 ? 55.513  107.714 98.383  1.00 144.49 ? 572 ASP B OD1 1 
ATOM   6829 O OD2 . ASP B 2 583 ? 53.506  107.733 97.494  1.00 144.49 ? 572 ASP B OD2 1 
ATOM   6830 N N   . VAL B 2 584 ? 55.887  112.482 100.210 1.00 145.52 ? 573 VAL B N   1 
ATOM   6831 C CA  . VAL B 2 584 ? 55.952  113.932 100.327 1.00 145.52 ? 573 VAL B CA  1 
ATOM   6832 C C   . VAL B 2 584 ? 57.267  114.308 100.995 1.00 145.52 ? 573 VAL B C   1 
ATOM   6833 O O   . VAL B 2 584 ? 58.031  113.452 101.446 1.00 145.52 ? 573 VAL B O   1 
ATOM   6834 C CB  . VAL B 2 584 ? 54.760  114.521 101.116 1.00 145.52 ? 573 VAL B CB  1 
ATOM   6835 C CG1 . VAL B 2 584 ? 53.439  114.100 100.490 1.00 145.52 ? 573 VAL B CG1 1 
ATOM   6836 C CG2 . VAL B 2 584 ? 54.824  114.096 102.571 1.00 145.52 ? 573 VAL B CG2 1 
ATOM   6837 N N   . GLY B 2 585 ? 57.529  115.611 101.041 1.00 145.79 ? 574 GLY B N   1 
ATOM   6838 C CA  . GLY B 2 585 ? 58.739  116.095 101.686 1.00 145.79 ? 574 GLY B CA  1 
ATOM   6839 C C   . GLY B 2 585 ? 58.619  116.015 103.198 1.00 145.79 ? 574 GLY B C   1 
ATOM   6840 O O   . GLY B 2 585 ? 57.796  116.708 103.808 1.00 145.79 ? 574 GLY B O   1 
ATOM   6841 N N   . LEU B 2 586 ? 59.443  115.170 103.811 1.00 144.97 ? 575 LEU B N   1 
ATOM   6842 C CA  . LEU B 2 586 ? 59.428  114.963 105.251 1.00 144.97 ? 575 LEU B CA  1 
ATOM   6843 C C   . LEU B 2 586 ? 60.579  115.713 105.905 1.00 144.97 ? 575 LEU B C   1 
ATOM   6844 O O   . LEU B 2 586 ? 61.558  116.082 105.249 1.00 144.97 ? 575 LEU B O   1 
ATOM   6845 C CB  . LEU B 2 586 ? 59.521  113.475 105.612 1.00 144.97 ? 575 LEU B CB  1 
ATOM   6846 C CG  . LEU B 2 586 ? 58.218  112.691 105.788 1.00 144.97 ? 575 LEU B CG  1 
ATOM   6847 C CD1 . LEU B 2 586 ? 57.350  113.318 106.871 1.00 144.97 ? 575 LEU B CD1 1 
ATOM   6848 C CD2 . LEU B 2 586 ? 57.456  112.569 104.482 1.00 144.97 ? 575 LEU B CD2 1 
ATOM   6849 N N   . SER B 2 587 ? 60.449  115.933 107.209 1.00 145.46 ? 576 SER B N   1 
ATOM   6850 C CA  . SER B 2 587 ? 61.463  116.613 108.003 1.00 145.46 ? 576 SER B CA  1 
ATOM   6851 C C   . SER B 2 587 ? 62.078  115.619 108.980 1.00 145.46 ? 576 SER B C   1 
ATOM   6852 O O   . SER B 2 587 ? 61.358  114.977 109.752 1.00 145.46 ? 576 SER B O   1 
ATOM   6853 C CB  . SER B 2 587 ? 60.858  117.800 108.750 1.00 145.46 ? 576 SER B CB  1 
ATOM   6854 O OG  . SER B 2 587 ? 60.002  118.547 107.904 1.00 145.46 ? 576 SER B OG  1 
ATOM   6855 N N   . ALA B 2 588 ? 63.402  115.491 108.942 1.00 145.53 ? 577 ALA B N   1 
ATOM   6856 C CA  . ALA B 2 588 ? 64.121  114.593 109.844 1.00 145.53 ? 577 ALA B CA  1 
ATOM   6857 C C   . ALA B 2 588 ? 64.425  115.342 111.134 1.00 145.53 ? 577 ALA B C   1 
ATOM   6858 O O   . ALA B 2 588 ? 65.455  116.004 111.268 1.00 145.53 ? 577 ALA B O   1 
ATOM   6859 C CB  . ALA B 2 588 ? 65.394  114.073 109.192 1.00 145.53 ? 577 ALA B CB  1 
ATOM   6860 N N   . GLY B 2 589 ? 63.510  115.235 112.099 1.00 145.71 ? 578 GLY B N   1 
ATOM   6861 C CA  . GLY B 2 589 ? 63.739  115.863 113.390 1.00 145.71 ? 578 GLY B CA  1 
ATOM   6862 C C   . GLY B 2 589 ? 64.958  115.305 114.097 1.00 145.71 ? 578 GLY B C   1 
ATOM   6863 O O   . GLY B 2 589 ? 65.797  116.058 114.598 1.00 145.71 ? 578 GLY B O   1 
ATOM   6864 N N   . LEU B 2 590 ? 65.069  113.977 114.149 1.00 143.64 ? 579 LEU B N   1 
ATOM   6865 C CA  . LEU B 2 590 ? 66.232  113.289 114.711 1.00 143.64 ? 579 LEU B CA  1 
ATOM   6866 C C   . LEU B 2 590 ? 66.464  113.650 116.175 1.00 143.64 ? 579 LEU B C   1 
ATOM   6867 O O   . LEU B 2 590 ? 67.577  114.003 116.573 1.00 143.64 ? 579 LEU B O   1 
ATOM   6868 C CB  . LEU B 2 590 ? 67.491  113.560 113.883 1.00 143.64 ? 579 LEU B CB  1 
ATOM   6869 C CG  . LEU B 2 590 ? 67.878  112.427 112.932 1.00 143.64 ? 579 LEU B CG  1 
ATOM   6870 C CD1 . LEU B 2 590 ? 66.767  112.153 111.937 1.00 143.64 ? 579 LEU B CD1 1 
ATOM   6871 C CD2 . LEU B 2 590 ? 69.165  112.757 112.204 1.00 143.64 ? 579 LEU B CD2 1 
ATOM   6872 N N   . GLN B 2 591 ? 65.412  113.570 116.984 1.00 142.80 ? 580 GLN B N   1 
ATOM   6873 C CA  . GLN B 2 591 ? 65.568  113.668 118.429 1.00 142.80 ? 580 GLN B CA  1 
ATOM   6874 C C   . GLN B 2 591 ? 65.714  112.271 119.020 1.00 142.80 ? 580 GLN B C   1 
ATOM   6875 O O   . GLN B 2 591 ? 64.851  111.409 118.824 1.00 142.80 ? 580 GLN B O   1 
ATOM   6876 C CB  . GLN B 2 591 ? 64.376  114.407 119.045 1.00 142.80 ? 580 GLN B CB  1 
ATOM   6877 C CG  . GLN B 2 591 ? 63.001  113.791 118.784 1.00 142.80 ? 580 GLN B CG  1 
ATOM   6878 C CD  . GLN B 2 591 ? 62.446  114.121 117.410 1.00 142.80 ? 580 GLN B CD  1 
ATOM   6879 O OE1 . GLN B 2 591 ? 63.159  114.621 116.541 1.00 142.80 ? 580 GLN B OE1 1 
ATOM   6880 N NE2 . GLN B 2 591 ? 61.163  113.841 117.209 1.00 142.80 ? 580 GLN B NE2 1 
ATOM   6881 N N   . ALA B 2 592 ? 66.821  112.030 119.722 1.00 141.70 ? 581 ALA B N   1 
ATOM   6882 C CA  . ALA B 2 592 ? 67.103  110.710 120.275 1.00 141.70 ? 581 ALA B CA  1 
ATOM   6883 C C   . ALA B 2 592 ? 67.046  110.725 121.798 1.00 141.70 ? 581 ALA B C   1 
ATOM   6884 O O   . ALA B 2 592 ? 66.235  110.007 122.388 1.00 141.70 ? 581 ALA B O   1 
ATOM   6885 C CB  . ALA B 2 592 ? 68.466  110.218 119.784 1.00 141.70 ? 581 ALA B CB  1 
ATOM   6886 N N   . SER B 2 593 ? 67.891  111.525 122.453 1.00 143.14 ? 582 SER B N   1 
ATOM   6887 C CA  . SER B 2 593 ? 67.842  111.738 123.897 1.00 143.14 ? 582 SER B CA  1 
ATOM   6888 C C   . SER B 2 593 ? 67.922  110.440 124.697 1.00 143.14 ? 582 SER B C   1 
ATOM   6889 O O   . SER B 2 593 ? 67.727  110.450 125.916 1.00 143.14 ? 582 SER B O   1 
ATOM   6890 C CB  . SER B 2 593 ? 66.571  112.503 124.275 1.00 143.14 ? 582 SER B CB  1 
ATOM   6891 O OG  . SER B 2 593 ? 66.569  112.840 125.651 1.00 143.14 ? 582 SER B OG  1 
ATOM   6892 N N   . ASP B 2 594 ? 68.209  109.320 124.030 1.00 141.73 ? 583 ASP B N   1 
ATOM   6893 C CA  . ASP B 2 594 ? 68.146  108.020 124.682 1.00 141.73 ? 583 ASP B CA  1 
ATOM   6894 C C   . ASP B 2 594 ? 69.326  107.113 124.358 1.00 141.73 ? 583 ASP B C   1 
ATOM   6895 O O   . ASP B 2 594 ? 69.519  106.114 125.059 1.00 141.73 ? 583 ASP B O   1 
ATOM   6896 C CB  . ASP B 2 594 ? 66.836  107.306 124.303 1.00 141.73 ? 583 ASP B CB  1 
ATOM   6897 C CG  . ASP B 2 594 ? 66.257  106.496 125.448 1.00 141.73 ? 583 ASP B CG  1 
ATOM   6898 O OD1 . ASP B 2 594 ? 67.028  105.812 126.153 1.00 141.73 ? 583 ASP B OD1 1 
ATOM   6899 O OD2 . ASP B 2 594 ? 65.024  106.543 125.643 1.00 141.73 ? 583 ASP B OD2 1 
ATOM   6900 N N   . LEU B 2 595 ? 70.116  107.421 123.337 1.00 137.18 ? 584 LEU B N   1 
ATOM   6901 C CA  . LEU B 2 595 ? 71.248  106.577 122.997 1.00 137.18 ? 584 LEU B CA  1 
ATOM   6902 C C   . LEU B 2 595 ? 72.350  106.717 124.045 1.00 137.18 ? 584 LEU B C   1 
ATOM   6903 O O   . LEU B 2 595 ? 72.483  107.769 124.678 1.00 137.18 ? 584 LEU B O   1 
ATOM   6904 C CB  . LEU B 2 595 ? 71.790  106.945 121.621 1.00 137.18 ? 584 LEU B CB  1 
ATOM   6905 C CG  . LEU B 2 595 ? 70.746  107.033 120.507 1.00 137.18 ? 584 LEU B CG  1 
ATOM   6906 C CD1 . LEU B 2 595 ? 71.418  107.246 119.165 1.00 137.18 ? 584 LEU B CD1 1 
ATOM   6907 C CD2 . LEU B 2 595 ? 69.883  105.783 120.480 1.00 137.18 ? 584 LEU B CD2 1 
ATOM   6908 N N   . PRO B 2 596 ? 73.142  105.667 124.256 1.00 137.95 ? 585 PRO B N   1 
ATOM   6909 C CA  . PRO B 2 596 ? 74.201  105.725 125.272 1.00 137.95 ? 585 PRO B CA  1 
ATOM   6910 C C   . PRO B 2 596 ? 75.225  106.809 124.966 1.00 137.95 ? 585 PRO B C   1 
ATOM   6911 O O   . PRO B 2 596 ? 75.260  107.400 123.884 1.00 137.95 ? 585 PRO B O   1 
ATOM   6912 C CB  . PRO B 2 596 ? 74.829  104.328 125.211 1.00 137.95 ? 585 PRO B CB  1 
ATOM   6913 C CG  . PRO B 2 596 ? 73.749  103.458 124.661 1.00 137.95 ? 585 PRO B CG  1 
ATOM   6914 C CD  . PRO B 2 596 ? 73.009  104.319 123.678 1.00 137.95 ? 585 PRO B CD  1 
ATOM   6915 N N   . ALA B 2 597 ? 76.082  107.066 125.959 1.00 134.32 ? 586 ALA B N   1 
ATOM   6916 C CA  . ALA B 2 597 ? 77.110  108.089 125.806 1.00 134.32 ? 586 ALA B CA  1 
ATOM   6917 C C   . ALA B 2 597 ? 78.116  107.717 124.726 1.00 134.32 ? 586 ALA B C   1 
ATOM   6918 O O   . ALA B 2 597 ? 78.756  108.600 124.143 1.00 134.32 ? 586 ALA B O   1 
ATOM   6919 C CB  . ALA B 2 597 ? 77.821  108.325 127.137 1.00 134.32 ? 586 ALA B CB  1 
ATOM   6920 N N   . SER B 2 598 ? 78.274  106.422 124.446 1.00 130.81 ? 587 SER B N   1 
ATOM   6921 C CA  . SER B 2 598 ? 79.085  105.976 123.319 1.00 130.81 ? 587 SER B CA  1 
ATOM   6922 C C   . SER B 2 598 ? 78.437  106.278 121.975 1.00 130.81 ? 587 SER B C   1 
ATOM   6923 O O   . SER B 2 598 ? 79.031  105.969 120.936 1.00 130.81 ? 587 SER B O   1 
ATOM   6924 C CB  . SER B 2 598 ? 79.361  104.476 123.433 1.00 130.81 ? 587 SER B CB  1 
ATOM   6925 O OG  . SER B 2 598 ? 79.943  103.975 122.243 1.00 130.81 ? 587 SER B OG  1 
ATOM   6926 N N   . ALA B 2 599 ? 77.245  106.866 121.973 1.00 129.63 ? 588 ALA B N   1 
ATOM   6927 C CA  . ALA B 2 599 ? 76.502  107.206 120.767 1.00 129.63 ? 588 ALA B CA  1 
ATOM   6928 C C   . ALA B 2 599 ? 76.116  108.676 120.789 1.00 129.63 ? 588 ALA B C   1 
ATOM   6929 O O   . ALA B 2 599 ? 74.968  109.052 120.543 1.00 129.63 ? 588 ALA B O   1 
ATOM   6930 C CB  . ALA B 2 599 ? 75.268  106.322 120.626 1.00 129.63 ? 588 ALA B CB  1 
ATOM   6931 N N   . SER B 2 600 ? 77.084  109.534 121.100 1.00 131.60 ? 589 SER B N   1 
ATOM   6932 C CA  . SER B 2 600 ? 76.836  110.967 121.165 1.00 131.60 ? 589 SER B CA  1 
ATOM   6933 C C   . SER B 2 600 ? 76.639  111.524 119.761 1.00 131.60 ? 589 SER B C   1 
ATOM   6934 O O   . SER B 2 600 ? 77.543  111.458 118.923 1.00 131.60 ? 589 SER B O   1 
ATOM   6935 C CB  . SER B 2 600 ? 77.992  111.681 121.864 1.00 131.60 ? 589 SER B CB  1 
ATOM   6936 O OG  . SER B 2 600 ? 77.847  111.626 123.273 1.00 131.60 ? 589 SER B OG  1 
ATOM   6937 N N   . LEU B 2 601 ? 75.459  112.071 119.510 1.00 132.12 ? 590 LEU B N   1 
ATOM   6938 C CA  . LEU B 2 601 ? 75.134  112.574 118.183 1.00 132.12 ? 590 LEU B CA  1 
ATOM   6939 C C   . LEU B 2 601 ? 75.845  113.899 117.937 1.00 132.12 ? 590 LEU B C   1 
ATOM   6940 O O   . LEU B 2 601 ? 75.713  114.825 118.744 1.00 132.12 ? 590 LEU B O   1 
ATOM   6941 C CB  . LEU B 2 601 ? 73.629  112.762 118.037 1.00 132.12 ? 590 LEU B CB  1 
ATOM   6942 C CG  . LEU B 2 601 ? 72.783  111.493 118.107 1.00 132.12 ? 590 LEU B CG  1 
ATOM   6943 C CD1 . LEU B 2 601 ? 71.306  111.842 118.084 1.00 132.12 ? 590 LEU B CD1 1 
ATOM   6944 C CD2 . LEU B 2 601 ? 73.135  110.557 116.966 1.00 132.12 ? 590 LEU B CD2 1 
ATOM   6945 N N   . PRO B 2 602 ? 76.597  114.029 116.851 1.00 135.35 ? 591 PRO B N   1 
ATOM   6946 C CA  . PRO B 2 602 ? 77.180  115.325 116.501 1.00 135.35 ? 591 PRO B CA  1 
ATOM   6947 C C   . PRO B 2 602 ? 76.137  116.231 115.859 1.00 135.35 ? 591 PRO B C   1 
ATOM   6948 O O   . PRO B 2 602 ? 75.275  115.794 115.096 1.00 135.35 ? 591 PRO B O   1 
ATOM   6949 C CB  . PRO B 2 602 ? 78.284  114.954 115.509 1.00 135.35 ? 591 PRO B CB  1 
ATOM   6950 C CG  . PRO B 2 602 ? 77.762  113.732 114.841 1.00 135.35 ? 591 PRO B CG  1 
ATOM   6951 C CD  . PRO B 2 602 ? 76.960  112.982 115.881 1.00 135.35 ? 591 PRO B CD  1 
ATOM   6952 N N   . ALA B 2 603 ? 76.228  117.519 116.194 1.00 141.10 ? 592 ALA B N   1 
ATOM   6953 C CA  . ALA B 2 603 ? 75.297  118.489 115.632 1.00 141.10 ? 592 ALA B CA  1 
ATOM   6954 C C   . ALA B 2 603 ? 75.423  118.583 114.118 1.00 141.10 ? 592 ALA B C   1 
ATOM   6955 O O   . ALA B 2 603 ? 74.451  118.934 113.440 1.00 141.10 ? 592 ALA B O   1 
ATOM   6956 C CB  . ALA B 2 603 ? 75.520  119.863 116.265 1.00 141.10 ? 592 ALA B CB  1 
ATOM   6957 N N   . LYS B 2 604 ? 76.598  118.276 113.575 1.00 141.10 ? 593 LYS B N   1 
ATOM   6958 C CA  . LYS B 2 604 ? 76.819  118.214 112.137 1.00 141.10 ? 593 LYS B CA  1 
ATOM   6959 C C   . LYS B 2 604 ? 77.498  116.894 111.804 1.00 141.10 ? 593 LYS B C   1 
ATOM   6960 O O   . LYS B 2 604 ? 78.528  116.555 112.396 1.00 141.10 ? 593 LYS B O   1 
ATOM   6961 C CB  . LYS B 2 604 ? 77.657  119.404 111.655 1.00 141.10 ? 593 LYS B CB  1 
ATOM   6962 C CG  . LYS B 2 604 ? 78.944  119.631 112.434 1.00 141.10 ? 593 LYS B CG  1 
ATOM   6963 C CD  . LYS B 2 604 ? 79.986  120.335 111.582 1.00 141.10 ? 593 LYS B CD  1 
ATOM   6964 C CE  . LYS B 2 604 ? 79.499  121.705 111.138 1.00 141.10 ? 593 LYS B CE  1 
ATOM   6965 N NZ  . LYS B 2 604 ? 80.357  122.278 110.065 1.00 141.10 ? 593 LYS B NZ  1 
ATOM   6966 N N   . ALA B 2 605 ? 76.917  116.148 110.868 1.00 135.15 ? 594 ALA B N   1 
ATOM   6967 C CA  . ALA B 2 605 ? 77.398  114.821 110.519 1.00 135.15 ? 594 ALA B CA  1 
ATOM   6968 C C   . ALA B 2 605 ? 77.731  114.750 109.036 1.00 135.15 ? 594 ALA B C   1 
ATOM   6969 O O   . ALA B 2 605 ? 77.160  115.476 108.218 1.00 135.15 ? 594 ALA B O   1 
ATOM   6970 C CB  . ALA B 2 605 ? 76.363  113.748 110.869 1.00 135.15 ? 594 ALA B CB  1 
ATOM   6971 N N   . ASP B 2 606 ? 78.651  113.850 108.699 1.00 129.28 ? 595 ASP B N   1 
ATOM   6972 C CA  . ASP B 2 606 ? 79.094  113.671 107.325 1.00 129.28 ? 595 ASP B CA  1 
ATOM   6973 C C   . ASP B 2 606 ? 77.986  113.017 106.498 1.00 129.28 ? 595 ASP B C   1 
ATOM   6974 O O   . ASP B 2 606 ? 76.866  112.799 106.966 1.00 129.28 ? 595 ASP B O   1 
ATOM   6975 C CB  . ASP B 2 606 ? 80.375  112.839 107.295 1.00 129.28 ? 595 ASP B CB  1 
ATOM   6976 C CG  . ASP B 2 606 ? 81.136  112.980 105.994 1.00 129.28 ? 595 ASP B CG  1 
ATOM   6977 O OD1 . ASP B 2 606 ? 80.836  112.224 105.047 1.00 129.28 ? 595 ASP B OD1 1 
ATOM   6978 O OD2 . ASP B 2 606 ? 82.030  113.846 105.917 1.00 129.28 ? 595 ASP B OD2 1 
ATOM   6979 N N   . LEU B 2 607 ? 78.297  112.714 105.241 1.00 127.78 ? 596 LEU B N   1 
ATOM   6980 C CA  . LEU B 2 607 ? 77.349  112.039 104.361 1.00 127.78 ? 596 LEU B CA  1 
ATOM   6981 C C   . LEU B 2 607 ? 78.130  111.225 103.344 1.00 127.78 ? 596 LEU B C   1 
ATOM   6982 O O   . LEU B 2 607 ? 78.846  111.793 102.514 1.00 127.78 ? 596 LEU B O   1 
ATOM   6983 C CB  . LEU B 2 607 ? 76.435  113.046 103.664 1.00 127.78 ? 596 LEU B CB  1 
ATOM   6984 C CG  . LEU B 2 607 ? 75.195  112.491 102.965 1.00 127.78 ? 596 LEU B CG  1 
ATOM   6985 C CD1 . LEU B 2 607 ? 74.062  113.492 103.067 1.00 127.78 ? 596 LEU B CD1 1 
ATOM   6986 C CD2 . LEU B 2 607 ? 75.482  112.163 101.510 1.00 127.78 ? 596 LEU B CD2 1 
ATOM   6987 N N   . LEU B 2 608 ? 77.988  109.901 103.405 1.00 125.13 ? 597 LEU B N   1 
ATOM   6988 C CA  . LEU B 2 608 ? 78.692  109.011 102.490 1.00 125.13 ? 597 LEU B CA  1 
ATOM   6989 C C   . LEU B 2 608 ? 77.987  108.875 101.150 1.00 125.13 ? 597 LEU B C   1 
ATOM   6990 O O   . LEU B 2 608 ? 78.651  108.797 100.110 1.00 125.13 ? 597 LEU B O   1 
ATOM   6991 C CB  . LEU B 2 608 ? 78.865  107.627 103.119 1.00 125.13 ? 597 LEU B CB  1 
ATOM   6992 C CG  . LEU B 2 608 ? 80.232  107.368 103.747 1.00 125.13 ? 597 LEU B CG  1 
ATOM   6993 C CD1 . LEU B 2 608 ? 81.308  107.354 102.677 1.00 125.13 ? 597 LEU B CD1 1 
ATOM   6994 C CD2 . LEU B 2 608 ? 80.530  108.427 104.782 1.00 125.13 ? 597 LEU B CD2 1 
ATOM   6995 N N   . LEU B 2 609 ? 76.658  108.841 101.155 1.00 125.91 ? 598 LEU B N   1 
ATOM   6996 C CA  . LEU B 2 609 ? 75.878  108.693 99.933  1.00 125.91 ? 598 LEU B CA  1 
ATOM   6997 C C   . LEU B 2 609 ? 74.411  108.909 100.271 1.00 125.91 ? 598 LEU B C   1 
ATOM   6998 O O   . LEU B 2 609 ? 74.016  108.930 101.439 1.00 125.91 ? 598 LEU B O   1 
ATOM   6999 C CB  . LEU B 2 609 ? 76.098  107.324 99.282  1.00 125.91 ? 598 LEU B CB  1 
ATOM   7000 C CG  . LEU B 2 609 ? 75.895  106.084 100.151 1.00 125.91 ? 598 LEU B CG  1 
ATOM   7001 C CD1 . LEU B 2 609 ? 74.467  105.574 100.072 1.00 125.91 ? 598 LEU B CD1 1 
ATOM   7002 C CD2 . LEU B 2 609 ? 76.878  105.003 99.740  1.00 125.91 ? 598 LEU B CD2 1 
ATOM   7003 N N   . SER B 2 610 ? 73.609  109.066 99.223  1.00 128.48 ? 599 SER B N   1 
ATOM   7004 C CA  . SER B 2 610 ? 72.175  109.255 99.356  1.00 128.48 ? 599 SER B CA  1 
ATOM   7005 C C   . SER B 2 610 ? 71.476  108.504 98.236  1.00 128.48 ? 599 SER B C   1 
ATOM   7006 O O   . SER B 2 610 ? 71.974  108.436 97.110  1.00 128.48 ? 599 SER B O   1 
ATOM   7007 C CB  . SER B 2 610 ? 71.796  110.739 99.309  1.00 128.48 ? 599 SER B CB  1 
ATOM   7008 O OG  . SER B 2 610 ? 72.035  111.362 100.556 1.00 128.48 ? 599 SER B OG  1 
ATOM   7009 N N   . THR B 2 611 ? 70.312  107.936 98.557  1.00 127.67 ? 600 THR B N   1 
ATOM   7010 C CA  . THR B 2 611 ? 69.548  107.211 97.551  1.00 127.67 ? 600 THR B CA  1 
ATOM   7011 C C   . THR B 2 611 ? 69.106  108.107 96.403  1.00 127.67 ? 600 THR B C   1 
ATOM   7012 O O   . THR B 2 611 ? 68.819  107.601 95.314  1.00 127.67 ? 600 THR B O   1 
ATOM   7013 C CB  . THR B 2 611 ? 68.329  106.547 98.189  1.00 127.67 ? 600 THR B CB  1 
ATOM   7014 O OG1 . THR B 2 611 ? 67.575  107.527 98.909  1.00 127.67 ? 600 THR B OG1 1 
ATOM   7015 C CG2 . THR B 2 611 ? 68.763  105.446 99.142  1.00 127.67 ? 600 THR B CG2 1 
ATOM   7016 N N   . GLN B 2 612 ? 69.044  109.419 96.616  1.00 131.89 ? 601 GLN B N   1 
ATOM   7017 C CA  . GLN B 2 612 ? 68.727  110.338 95.542  1.00 131.89 ? 601 GLN B CA  1 
ATOM   7018 C C   . GLN B 2 612 ? 69.899  111.275 95.283  1.00 131.89 ? 601 GLN B C   1 
ATOM   7019 O O   . GLN B 2 612 ? 70.402  111.910 96.216  1.00 131.89 ? 601 GLN B O   1 
ATOM   7020 C CB  . GLN B 2 612 ? 67.477  111.165 95.871  1.00 131.89 ? 601 GLN B CB  1 
ATOM   7021 C CG  . GLN B 2 612 ? 66.346  110.363 96.486  1.00 131.89 ? 601 GLN B CG  1 
ATOM   7022 C CD  . GLN B 2 612 ? 66.025  109.107 95.699  1.00 131.89 ? 601 GLN B CD  1 
ATOM   7023 O OE1 . GLN B 2 612 ? 65.967  109.127 94.469  1.00 131.89 ? 601 GLN B OE1 1 
ATOM   7024 N NE2 . GLN B 2 612 ? 65.817  108.004 96.407  1.00 131.89 ? 601 GLN B NE2 1 
ATOM   7025 N N   . PRO B 2 613 ? 70.360  111.378 94.039  1.00 133.24 ? 602 PRO B N   1 
ATOM   7026 C CA  . PRO B 2 613 ? 71.434  112.328 93.736  1.00 133.24 ? 602 PRO B CA  1 
ATOM   7027 C C   . PRO B 2 613 ? 70.933  113.760 93.833  1.00 133.24 ? 602 PRO B C   1 
ATOM   7028 O O   . PRO B 2 613 ? 69.797  114.068 93.466  1.00 133.24 ? 602 PRO B O   1 
ATOM   7029 C CB  . PRO B 2 613 ? 71.839  111.965 92.304  1.00 133.24 ? 602 PRO B CB  1 
ATOM   7030 C CG  . PRO B 2 613 ? 70.623  111.338 91.718  1.00 133.24 ? 602 PRO B CG  1 
ATOM   7031 C CD  . PRO B 2 613 ? 69.909  110.644 92.844  1.00 133.24 ? 602 PRO B CD  1 
ATOM   7032 N N   . GLY B 2 614 ? 71.795  114.637 94.338  1.00 136.93 ? 603 GLY B N   1 
ATOM   7033 C CA  . GLY B 2 614 ? 71.429  116.023 94.547  1.00 136.93 ? 603 GLY B CA  1 
ATOM   7034 C C   . GLY B 2 614 ? 72.057  116.599 95.797  1.00 136.93 ? 603 GLY B C   1 
ATOM   7035 O O   . GLY B 2 614 ? 72.168  117.820 95.944  1.00 136.93 ? 603 GLY B O   1 
ATOM   7036 N N   . ARG B 2 615 ? 72.472  115.725 96.708  1.00 137.20 ? 604 ARG B N   1 
ATOM   7037 C CA  . ARG B 2 615 ? 73.248  116.111 97.876  1.00 137.20 ? 604 ARG B CA  1 
ATOM   7038 C C   . ARG B 2 615 ? 74.663  115.580 97.714  1.00 137.20 ? 604 ARG B C   1 
ATOM   7039 O O   . ARG B 2 615 ? 74.867  114.375 97.535  1.00 137.20 ? 604 ARG B O   1 
ATOM   7040 C CB  . ARG B 2 615 ? 72.623  115.577 99.170  1.00 137.20 ? 604 ARG B CB  1 
ATOM   7041 C CG  . ARG B 2 615 ? 71.151  115.919 99.336  1.00 137.20 ? 604 ARG B CG  1 
ATOM   7042 C CD  . ARG B 2 615 ? 70.792  116.128 100.800 1.00 137.20 ? 604 ARG B CD  1 
ATOM   7043 N NE  . ARG B 2 615 ? 69.406  116.560 100.967 1.00 137.20 ? 604 ARG B NE  1 
ATOM   7044 C CZ  . ARG B 2 615 ? 68.908  117.058 102.094 1.00 137.20 ? 604 ARG B CZ  1 
ATOM   7045 N NH1 . ARG B 2 615 ? 69.682  117.191 103.162 1.00 137.20 ? 604 ARG B NH1 1 
ATOM   7046 N NH2 . ARG B 2 615 ? 67.635  117.424 102.153 1.00 137.20 ? 604 ARG B NH2 1 
ATOM   7047 N N   . GLU B 2 616 ? 75.636  116.481 97.774  1.00 134.01 ? 605 GLU B N   1 
ATOM   7048 C CA  . GLU B 2 616 ? 77.026  116.138 97.519  1.00 134.01 ? 605 GLU B CA  1 
ATOM   7049 C C   . GLU B 2 616 ? 77.594  115.349 98.690  1.00 134.01 ? 605 GLU B C   1 
ATOM   7050 O O   . GLU B 2 616 ? 77.278  115.622 99.851  1.00 134.01 ? 605 GLU B O   1 
ATOM   7051 C CB  . GLU B 2 616 ? 77.866  117.393 97.272  1.00 134.01 ? 605 GLU B CB  1 
ATOM   7052 C CG  . GLU B 2 616 ? 77.815  118.421 98.389  1.00 134.01 ? 605 GLU B CG  1 
ATOM   7053 C CD  . GLU B 2 616 ? 76.651  119.381 98.247  1.00 134.01 ? 605 GLU B CD  1 
ATOM   7054 O OE1 . GLU B 2 616 ? 76.897  120.597 98.106  1.00 134.01 ? 605 GLU B OE1 1 
ATOM   7055 O OE2 . GLU B 2 616 ? 75.491  118.921 98.279  1.00 134.01 ? 605 GLU B OE2 1 
ATOM   7056 N N   . GLU B 2 617 ? 78.426  114.362 98.373  1.00 129.04 ? 606 GLU B N   1 
ATOM   7057 C CA  . GLU B 2 617 ? 79.048  113.522 99.382  1.00 129.04 ? 606 GLU B CA  1 
ATOM   7058 C C   . GLU B 2 617 ? 80.360  114.145 99.836  1.00 129.04 ? 606 GLU B C   1 
ATOM   7059 O O   . GLU B 2 617 ? 81.127  114.670 99.025  1.00 129.04 ? 606 GLU B O   1 
ATOM   7060 C CB  . GLU B 2 617 ? 79.285  112.115 98.833  1.00 129.04 ? 606 GLU B CB  1 
ATOM   7061 C CG  . GLU B 2 617 ? 78.002  111.392 98.455  1.00 129.04 ? 606 GLU B CG  1 
ATOM   7062 C CD  . GLU B 2 617 ? 78.161  110.510 97.233  1.00 129.04 ? 606 GLU B CD  1 
ATOM   7063 O OE1 . GLU B 2 617 ? 79.311  110.161 96.894  1.00 129.04 ? 606 GLU B OE1 1 
ATOM   7064 O OE2 . GLU B 2 617 ? 77.135  110.161 96.612  1.00 129.04 ? 606 GLU B OE2 1 
ATOM   7065 N N   . GLY B 2 618 ? 80.609  114.084 101.140 1.00 131.25 ? 607 GLY B N   1 
ATOM   7066 C CA  . GLY B 2 618 ? 81.730  114.772 101.741 1.00 131.25 ? 607 GLY B CA  1 
ATOM   7067 C C   . GLY B 2 618 ? 81.379  116.097 102.377 1.00 131.25 ? 607 GLY B C   1 
ATOM   7068 O O   . GLY B 2 618 ? 82.289  116.836 102.771 1.00 131.25 ? 607 GLY B O   1 
ATOM   7069 N N   . SER B 2 619 ? 80.092  116.420 102.487 1.00 133.04 ? 608 SER B N   1 
ATOM   7070 C CA  . SER B 2 619 ? 79.653  117.671 103.083 1.00 133.04 ? 608 SER B CA  1 
ATOM   7071 C C   . SER B 2 619 ? 79.076  117.393 104.461 1.00 133.04 ? 608 SER B C   1 
ATOM   7072 O O   . SER B 2 619 ? 77.957  116.865 104.554 1.00 133.04 ? 608 SER B O   1 
ATOM   7073 C CB  . SER B 2 619 ? 78.611  118.349 102.198 1.00 133.04 ? 608 SER B CB  1 
ATOM   7074 O OG  . SER B 2 619 ? 77.354  117.706 102.316 1.00 133.04 ? 608 SER B OG  1 
ATOM   7075 N N   . PRO B 2 620 ? 79.781  117.719 105.548 1.00 136.79 ? 609 PRO B N   1 
ATOM   7076 C CA  . PRO B 2 620 ? 79.210  117.499 106.883 1.00 136.79 ? 609 PRO B CA  1 
ATOM   7077 C C   . PRO B 2 620 ? 77.991  118.375 107.118 1.00 136.79 ? 609 PRO B C   1 
ATOM   7078 O O   . PRO B 2 620 ? 78.103  119.597 107.254 1.00 136.79 ? 609 PRO B O   1 
ATOM   7079 C CB  . PRO B 2 620 ? 80.362  117.864 107.829 1.00 136.79 ? 609 PRO B CB  1 
ATOM   7080 C CG  . PRO B 2 620 ? 81.297  118.687 107.007 1.00 136.79 ? 609 PRO B CG  1 
ATOM   7081 C CD  . PRO B 2 620 ? 81.180  118.170 105.612 1.00 136.79 ? 609 PRO B CD  1 
ATOM   7082 N N   . LEU B 2 621 ? 76.822  117.747 107.176 1.00 140.48 ? 610 LEU B N   1 
ATOM   7083 C CA  . LEU B 2 621 ? 75.548  118.448 107.217 1.00 140.48 ? 610 LEU B CA  1 
ATOM   7084 C C   . LEU B 2 621 ? 75.009  118.491 108.641 1.00 140.48 ? 610 LEU B C   1 
ATOM   7085 O O   . LEU B 2 621 ? 75.035  117.487 109.358 1.00 140.48 ? 610 LEU B O   1 
ATOM   7086 C CB  . LEU B 2 621 ? 74.548  117.773 106.271 1.00 140.48 ? 610 LEU B CB  1 
ATOM   7087 C CG  . LEU B 2 621 ? 73.061  118.125 106.297 1.00 140.48 ? 610 LEU B CG  1 
ATOM   7088 C CD1 . LEU B 2 621 ? 72.506  118.068 104.890 1.00 140.48 ? 610 LEU B CD1 1 
ATOM   7089 C CD2 . LEU B 2 621 ? 72.309  117.139 107.168 1.00 140.48 ? 610 LEU B CD2 1 
ATOM   7090 N N   . GLU B 2 622 ? 74.526  119.666 109.042 1.00 145.36 ? 611 GLU B N   1 
ATOM   7091 C CA  . GLU B 2 622 ? 74.023  119.855 110.396 1.00 145.36 ? 611 GLU B CA  1 
ATOM   7092 C C   . GLU B 2 622 ? 72.784  119.003 110.641 1.00 145.36 ? 611 GLU B C   1 
ATOM   7093 O O   . GLU B 2 622 ? 71.950  118.814 109.753 1.00 145.36 ? 611 GLU B O   1 
ATOM   7094 C CB  . GLU B 2 622 ? 73.720  121.333 110.643 1.00 145.36 ? 611 GLU B CB  1 
ATOM   7095 C CG  . GLU B 2 622 ? 72.971  122.015 109.510 1.00 145.36 ? 611 GLU B CG  1 
ATOM   7096 C CD  . GLU B 2 622 ? 71.473  121.826 109.594 1.00 145.36 ? 611 GLU B CD  1 
ATOM   7097 O OE1 . GLU B 2 622 ? 70.963  121.548 110.700 1.00 145.36 ? 611 GLU B OE1 1 
ATOM   7098 O OE2 . GLU B 2 622 ? 70.807  121.947 108.546 1.00 145.36 ? 611 GLU B OE2 1 
ATOM   7099 N N   . LEU B 2 623 ? 72.660  118.501 111.870 1.00 145.45 ? 612 LEU B N   1 
ATOM   7100 C CA  . LEU B 2 623 ? 71.704  117.452 112.204 1.00 145.45 ? 612 LEU B CA  1 
ATOM   7101 C C   . LEU B 2 623 ? 70.347  118.009 112.630 1.00 145.45 ? 612 LEU B C   1 
ATOM   7102 O O   . LEU B 2 623 ? 69.577  117.319 113.306 1.00 145.45 ? 612 LEU B O   1 
ATOM   7103 C CB  . LEU B 2 623 ? 72.290  116.561 113.302 1.00 145.45 ? 612 LEU B CB  1 
ATOM   7104 C CG  . LEU B 2 623 ? 71.748  115.146 113.521 1.00 145.45 ? 612 LEU B CG  1 
ATOM   7105 C CD1 . LEU B 2 623 ? 72.456  114.170 112.597 1.00 145.45 ? 612 LEU B CD1 1 
ATOM   7106 C CD2 . LEU B 2 623 ? 71.901  114.728 114.974 1.00 145.45 ? 612 LEU B CD2 1 
ATOM   7107 N N   . GLU B 2 624 ? 70.027  119.243 112.246 1.00 148.25 ? 613 GLU B N   1 
ATOM   7108 C CA  . GLU B 2 624 ? 68.762  119.848 112.646 1.00 148.25 ? 613 GLU B CA  1 
ATOM   7109 C C   . GLU B 2 624 ? 67.848  120.156 111.472 1.00 148.25 ? 613 GLU B C   1 
ATOM   7110 O O   . GLU B 2 624 ? 66.695  119.707 111.458 1.00 148.25 ? 613 GLU B O   1 
ATOM   7111 C CB  . GLU B 2 624 ? 69.025  121.127 113.458 1.00 148.25 ? 613 GLU B CB  1 
ATOM   7112 C CG  . GLU B 2 624 ? 69.649  120.869 114.820 1.00 148.25 ? 613 GLU B CG  1 
ATOM   7113 C CD  . GLU B 2 624 ? 68.895  119.823 115.619 1.00 148.25 ? 613 GLU B CD  1 
ATOM   7114 O OE1 . GLU B 2 624 ? 67.648  119.885 115.661 1.00 148.25 ? 613 GLU B OE1 1 
ATOM   7115 O OE2 . GLU B 2 624 ? 69.550  118.935 116.202 1.00 148.25 ? 613 GLU B OE2 1 
ATOM   7116 N N   . ARG B 2 625 ? 68.322  120.905 110.480 1.00 149.16 ? 614 ARG B N   1 
ATOM   7117 C CA  . ARG B 2 625 ? 67.498  121.260 109.325 1.00 149.16 ? 614 ARG B CA  1 
ATOM   7118 C C   . ARG B 2 625 ? 67.716  120.235 108.213 1.00 149.16 ? 614 ARG B C   1 
ATOM   7119 O O   . ARG B 2 625 ? 68.689  120.271 107.458 1.00 149.16 ? 614 ARG B O   1 
ATOM   7120 C CB  . ARG B 2 625 ? 67.807  122.685 108.866 1.00 149.16 ? 614 ARG B CB  1 
ATOM   7121 C CG  . ARG B 2 625 ? 66.908  123.209 107.746 1.00 149.16 ? 614 ARG B CG  1 
ATOM   7122 C CD  . ARG B 2 625 ? 67.507  122.968 106.365 1.00 149.16 ? 614 ARG B CD  1 
ATOM   7123 N NE  . ARG B 2 625 ? 66.497  122.997 105.311 1.00 149.16 ? 614 ARG B NE  1 
ATOM   7124 C CZ  . ARG B 2 625 ? 66.753  122.788 104.024 1.00 149.16 ? 614 ARG B CZ  1 
ATOM   7125 N NH1 . ARG B 2 625 ? 67.992  122.532 103.624 1.00 149.16 ? 614 ARG B NH1 1 
ATOM   7126 N NH2 . ARG B 2 625 ? 65.771  122.832 103.135 1.00 149.16 ? 614 ARG B NH2 1 
ATOM   7127 N N   . LEU B 2 626 ? 66.782  119.292 108.140 1.00 146.98 ? 615 LEU B N   1 
ATOM   7128 C CA  . LEU B 2 626 ? 66.792  118.257 107.117 1.00 146.98 ? 615 LEU B CA  1 
ATOM   7129 C C   . LEU B 2 626 ? 65.413  118.158 106.481 1.00 146.98 ? 615 LEU B C   1 
ATOM   7130 O O   . LEU B 2 626 ? 64.411  117.980 107.182 1.00 146.98 ? 615 LEU B O   1 
ATOM   7131 C CB  . LEU B 2 626 ? 67.200  116.904 107.704 1.00 146.98 ? 615 LEU B CB  1 
ATOM   7132 C CG  . LEU B 2 626 ? 68.670  116.700 108.080 1.00 146.98 ? 615 LEU B CG  1 
ATOM   7133 C CD1 . LEU B 2 626 ? 68.967  117.237 109.473 1.00 146.98 ? 615 LEU B CD1 1 
ATOM   7134 C CD2 . LEU B 2 626 ? 69.046  115.232 107.980 1.00 146.98 ? 615 LEU B CD2 1 
ATOM   7135 N N   . LYS B 2 627 ? 65.365  118.273 105.157 1.00 146.36 ? 616 LYS B N   1 
ATOM   7136 C CA  . LYS B 2 627 ? 64.131  118.131 104.397 1.00 146.36 ? 616 LYS B CA  1 
ATOM   7137 C C   . LYS B 2 627 ? 64.263  116.905 103.507 1.00 146.36 ? 616 LYS B C   1 
ATOM   7138 O O   . LYS B 2 627 ? 65.020  116.920 102.530 1.00 146.36 ? 616 LYS B O   1 
ATOM   7139 C CB  . LYS B 2 627 ? 63.844  119.383 103.565 1.00 146.36 ? 616 LYS B CB  1 
ATOM   7140 C CG  . LYS B 2 627 ? 63.119  120.479 104.332 1.00 146.36 ? 616 LYS B CG  1 
ATOM   7141 C CD  . LYS B 2 627 ? 61.638  120.170 104.483 1.00 146.36 ? 616 LYS B CD  1 
ATOM   7142 C CE  . LYS B 2 627 ? 61.073  120.793 105.750 1.00 146.36 ? 616 LYS B CE  1 
ATOM   7143 N NZ  . LYS B 2 627 ? 59.587  120.871 105.722 1.00 146.36 ? 616 LYS B NZ  1 
ATOM   7144 N N   . LEU B 2 628 ? 63.527  115.850 103.847 1.00 142.95 ? 617 LEU B N   1 
ATOM   7145 C CA  . LEU B 2 628 ? 63.634  114.558 103.179 1.00 142.95 ? 617 LEU B CA  1 
ATOM   7146 C C   . LEU B 2 628 ? 62.608  114.493 102.055 1.00 142.95 ? 617 LEU B C   1 
ATOM   7147 O O   . LEU B 2 628 ? 61.408  114.347 102.306 1.00 142.95 ? 617 LEU B O   1 
ATOM   7148 C CB  . LEU B 2 628 ? 63.429  113.417 104.175 1.00 142.95 ? 617 LEU B CB  1 
ATOM   7149 C CG  . LEU B 2 628 ? 64.640  112.861 104.932 1.00 142.95 ? 617 LEU B CG  1 
ATOM   7150 C CD1 . LEU B 2 628 ? 65.565  112.120 103.989 1.00 142.95 ? 617 LEU B CD1 1 
ATOM   7151 C CD2 . LEU B 2 628 ? 65.401  113.964 105.640 1.00 142.95 ? 617 LEU B CD2 1 
ATOM   7152 N N   . GLU B 2 629 ? 63.085  114.604 100.817 1.00 138.89 ? 618 GLU B N   1 
ATOM   7153 C CA  . GLU B 2 629 ? 62.231  114.418 99.661  1.00 138.89 ? 618 GLU B CA  1 
ATOM   7154 C C   . GLU B 2 629 ? 61.665  112.998 99.655  1.00 138.89 ? 618 GLU B C   1 
ATOM   7155 O O   . GLU B 2 629 ? 62.179  112.115 100.346 1.00 138.89 ? 618 GLU B O   1 
ATOM   7156 C CB  . GLU B 2 629 ? 63.017  114.694 98.381  1.00 138.89 ? 618 GLU B CB  1 
ATOM   7157 C CG  . GLU B 2 629 ? 64.299  113.901 98.256  1.00 138.89 ? 618 GLU B CG  1 
ATOM   7158 C CD  . GLU B 2 629 ? 64.821  113.864 96.836  1.00 138.89 ? 618 GLU B CD  1 
ATOM   7159 O OE1 . GLU B 2 629 ? 63.997  113.775 95.901  1.00 138.89 ? 618 GLU B OE1 1 
ATOM   7160 O OE2 . GLU B 2 629 ? 66.054  113.929 96.653  1.00 138.89 ? 618 GLU B OE2 1 
ATOM   7161 N N   . PRO B 2 630 ? 60.594  112.758 98.897  1.00 140.81 ? 619 PRO B N   1 
ATOM   7162 C CA  . PRO B 2 630 ? 59.990  111.418 98.881  1.00 140.81 ? 619 PRO B CA  1 
ATOM   7163 C C   . PRO B 2 630 ? 60.994  110.344 98.489  1.00 140.81 ? 619 PRO B C   1 
ATOM   7164 O O   . PRO B 2 630 ? 61.641  110.423 97.442  1.00 140.81 ? 619 PRO B O   1 
ATOM   7165 C CB  . PRO B 2 630 ? 58.871  111.549 97.842  1.00 140.81 ? 619 PRO B CB  1 
ATOM   7166 C CG  . PRO B 2 630 ? 58.526  112.988 97.843  1.00 140.81 ? 619 PRO B CG  1 
ATOM   7167 C CD  . PRO B 2 630 ? 59.791  113.733 98.137  1.00 140.81 ? 619 PRO B CD  1 
ATOM   7168 N N   . HIS B 2 631 ? 61.124  109.338 99.357  1.00 136.85 ? 620 HIS B N   1 
ATOM   7169 C CA  . HIS B 2 631 ? 61.966  108.166 99.110  1.00 136.85 ? 620 HIS B CA  1 
ATOM   7170 C C   . HIS B 2 631 ? 63.433  108.554 98.936  1.00 136.85 ? 620 HIS B C   1 
ATOM   7171 O O   . HIS B 2 631 ? 64.065  108.248 97.923  1.00 136.85 ? 620 HIS B O   1 
ATOM   7172 C CB  . HIS B 2 631 ? 61.463  107.372 97.903  1.00 136.85 ? 620 HIS B CB  1 
ATOM   7173 C CG  . HIS B 2 631 ? 60.059  106.878 98.048  1.00 136.85 ? 620 HIS B CG  1 
ATOM   7174 N ND1 . HIS B 2 631 ? 59.245  106.622 96.966  1.00 136.85 ? 620 HIS B ND1 1 
ATOM   7175 C CD2 . HIS B 2 631 ? 59.324  106.590 99.148  1.00 136.85 ? 620 HIS B CD2 1 
ATOM   7176 C CE1 . HIS B 2 631 ? 58.069  106.198 97.393  1.00 136.85 ? 620 HIS B CE1 1 
ATOM   7177 N NE2 . HIS B 2 631 ? 58.090  106.170 98.713  1.00 136.85 ? 620 HIS B NE2 1 
ATOM   7178 N N   . GLU B 2 632 ? 63.977  109.236 99.939  1.00 135.38 ? 621 GLU B N   1 
ATOM   7179 C CA  . GLU B 2 632 ? 65.389  109.584 99.970  1.00 135.38 ? 621 GLU B CA  1 
ATOM   7180 C C   . GLU B 2 632 ? 66.036  108.967 101.201 1.00 135.38 ? 621 GLU B C   1 
ATOM   7181 O O   . GLU B 2 632 ? 65.489  109.043 102.305 1.00 135.38 ? 621 GLU B O   1 
ATOM   7182 C CB  . GLU B 2 632 ? 65.592  111.102 99.968  1.00 135.38 ? 621 GLU B CB  1 
ATOM   7183 C CG  . GLU B 2 632 ? 67.053  111.533 99.934  1.00 135.38 ? 621 GLU B CG  1 
ATOM   7184 C CD  . GLU B 2 632 ? 67.296  112.855 100.637 1.00 135.38 ? 621 GLU B CD  1 
ATOM   7185 O OE1 . GLU B 2 632 ? 66.357  113.372 101.276 1.00 135.38 ? 621 GLU B OE1 1 
ATOM   7186 O OE2 . GLU B 2 632 ? 68.426  113.378 100.548 1.00 135.38 ? 621 GLU B OE2 1 
ATOM   7187 N N   . GLY B 2 633 ? 67.201  108.356 101.003 1.00 130.02 ? 622 GLY B N   1 
ATOM   7188 C CA  . GLY B 2 633 ? 67.913  107.707 102.085 1.00 130.02 ? 622 GLY B CA  1 
ATOM   7189 C C   . GLY B 2 633 ? 69.180  108.435 102.484 1.00 130.02 ? 622 GLY B C   1 
ATOM   7190 O O   . GLY B 2 633 ? 69.759  109.172 101.681 1.00 130.02 ? 622 GLY B O   1 
ATOM   7191 N N   . LEU B 2 634 ? 69.626  108.229 103.720 1.00 125.75 ? 623 LEU B N   1 
ATOM   7192 C CA  . LEU B 2 634 ? 70.761  108.961 104.259 1.00 125.75 ? 623 LEU B CA  1 
ATOM   7193 C C   . LEU B 2 634 ? 71.629  108.019 105.073 1.00 125.75 ? 623 LEU B C   1 
ATOM   7194 O O   . LEU B 2 634 ? 71.120  107.301 105.943 1.00 125.75 ? 623 LEU B O   1 
ATOM   7195 C CB  . LEU B 2 634 ? 70.292  110.124 105.136 1.00 125.75 ? 623 LEU B CB  1 
ATOM   7196 C CG  . LEU B 2 634 ? 69.923  111.448 104.470 1.00 125.75 ? 623 LEU B CG  1 
ATOM   7197 C CD1 . LEU B 2 634 ? 69.794  112.547 105.510 1.00 125.75 ? 623 LEU B CD1 1 
ATOM   7198 C CD2 . LEU B 2 634 ? 70.946  111.822 103.426 1.00 125.75 ? 623 LEU B CD2 1 
ATOM   7199 N N   . LEU B 2 635 ? 72.938  108.078 104.818 1.00 122.48 ? 624 LEU B N   1 
ATOM   7200 C CA  . LEU B 2 635 ? 73.954  107.222 105.419 1.00 122.48 ? 624 LEU B CA  1 
ATOM   7201 C C   . LEU B 2 635 ? 75.022  108.095 106.071 1.00 122.48 ? 624 LEU B C   1 
ATOM   7202 O O   . LEU B 2 635 ? 76.214  107.974 105.770 1.00 122.48 ? 624 LEU B O   1 
ATOM   7203 C CB  . LEU B 2 635 ? 74.568  106.285 104.372 1.00 122.48 ? 624 LEU B CB  1 
ATOM   7204 C CG  . LEU B 2 635 ? 75.558  105.204 104.836 1.00 122.48 ? 624 LEU B CG  1 
ATOM   7205 C CD1 . LEU B 2 635 ? 74.961  104.341 105.928 1.00 122.48 ? 624 LEU B CD1 1 
ATOM   7206 C CD2 . LEU B 2 635 ? 76.033  104.348 103.674 1.00 122.48 ? 624 LEU B CD2 1 
ATOM   7207 N N   . LEU B 2 636 ? 74.588  109.021 106.922 1.00 119.73 ? 625 LEU B N   1 
ATOM   7208 C CA  . LEU B 2 636 ? 75.509  109.937 107.574 1.00 119.73 ? 625 LEU B CA  1 
ATOM   7209 C C   . LEU B 2 636 ? 76.560  109.166 108.369 1.00 119.73 ? 625 LEU B C   1 
ATOM   7210 O O   . LEU B 2 636 ? 76.340  108.040 108.813 1.00 119.73 ? 625 LEU B O   1 
ATOM   7211 C CB  . LEU B 2 636 ? 74.754  110.888 108.502 1.00 119.73 ? 625 LEU B CB  1 
ATOM   7212 C CG  . LEU B 2 636 ? 73.635  111.748 107.907 1.00 119.73 ? 625 LEU B CG  1 
ATOM   7213 C CD1 . LEU B 2 636 ? 72.309  111.009 107.927 1.00 119.73 ? 625 LEU B CD1 1 
ATOM   7214 C CD2 . LEU B 2 636 ? 73.518  113.072 108.643 1.00 119.73 ? 625 LEU B CD2 1 
ATOM   7215 N N   . ARG B 2 637 ? 77.717  109.795 108.555 1.00 118.81 ? 626 ARG B N   1 
ATOM   7216 C CA  . ARG B 2 637 ? 78.821  109.171 109.266 1.00 118.81 ? 626 ARG B CA  1 
ATOM   7217 C C   . ARG B 2 637 ? 79.459  110.196 110.192 1.00 118.81 ? 626 ARG B C   1 
ATOM   7218 O O   . ARG B 2 637 ? 79.371  111.403 109.953 1.00 118.81 ? 626 ARG B O   1 
ATOM   7219 C CB  . ARG B 2 637 ? 79.861  108.611 108.284 1.00 118.81 ? 626 ARG B CB  1 
ATOM   7220 C CG  . ARG B 2 637 ? 80.945  107.771 108.925 1.00 118.81 ? 626 ARG B CG  1 
ATOM   7221 C CD  . ARG B 2 637 ? 81.865  107.140 107.893 1.00 118.81 ? 626 ARG B CD  1 
ATOM   7222 N NE  . ARG B 2 637 ? 82.736  108.122 107.254 1.00 118.81 ? 626 ARG B NE  1 
ATOM   7223 C CZ  . ARG B 2 637 ? 83.538  107.852 106.228 1.00 118.81 ? 626 ARG B CZ  1 
ATOM   7224 N NH1 . ARG B 2 637 ? 83.579  106.628 105.720 1.00 118.81 ? 626 ARG B NH1 1 
ATOM   7225 N NH2 . ARG B 2 637 ? 84.297  108.807 105.708 1.00 118.81 ? 626 ARG B NH2 1 
ATOM   7226 N N   . PHE B 2 638 ? 80.092  109.712 111.257 1.00 112.97 ? 627 PHE B N   1 
ATOM   7227 C CA  . PHE B 2 638 ? 80.881  110.573 112.127 1.00 112.97 ? 627 PHE B CA  1 
ATOM   7228 C C   . PHE B 2 638 ? 81.882  109.708 112.875 1.00 112.97 ? 627 PHE B C   1 
ATOM   7229 O O   . PHE B 2 638 ? 81.661  108.505 113.039 1.00 112.97 ? 627 PHE B O   1 
ATOM   7230 C CB  . PHE B 2 638 ? 79.991  111.354 113.109 1.00 112.97 ? 627 PHE B CB  1 
ATOM   7231 C CG  . PHE B 2 638 ? 78.824  110.573 113.640 1.00 112.97 ? 627 PHE B CG  1 
ATOM   7232 C CD1 . PHE B 2 638 ? 78.952  109.803 114.782 1.00 112.97 ? 627 PHE B CD1 1 
ATOM   7233 C CD2 . PHE B 2 638 ? 77.592  110.632 113.014 1.00 112.97 ? 627 PHE B CD2 1 
ATOM   7234 C CE1 . PHE B 2 638 ? 77.877  109.095 115.280 1.00 112.97 ? 627 PHE B CE1 1 
ATOM   7235 C CE2 . PHE B 2 638 ? 76.516  109.925 113.508 1.00 112.97 ? 627 PHE B CE2 1 
ATOM   7236 C CZ  . PHE B 2 638 ? 76.660  109.154 114.642 1.00 112.97 ? 627 PHE B CZ  1 
ATOM   7237 N N   . PRO B 2 639 ? 82.995  110.287 113.338 1.00 114.15 ? 628 PRO B N   1 
ATOM   7238 C CA  . PRO B 2 639 ? 84.001  109.480 114.040 1.00 114.15 ? 628 PRO B CA  1 
ATOM   7239 C C   . PRO B 2 639 ? 83.708  109.333 115.525 1.00 114.15 ? 628 PRO B C   1 
ATOM   7240 O O   . PRO B 2 639 ? 82.713  109.867 116.026 1.00 114.15 ? 628 PRO B O   1 
ATOM   7241 C CB  . PRO B 2 639 ? 85.298  110.256 113.796 1.00 114.15 ? 628 PRO B CB  1 
ATOM   7242 C CG  . PRO B 2 639 ? 84.855  111.672 113.691 1.00 114.15 ? 628 PRO B CG  1 
ATOM   7243 C CD  . PRO B 2 639 ? 83.460  111.666 113.108 1.00 114.15 ? 628 PRO B CD  1 
ATOM   7244 N N   . TYR B 2 640 ? 84.568  108.602 116.231 1.00 113.42 ? 629 TYR B N   1 
ATOM   7245 C CA  . TYR B 2 640 ? 84.351  108.316 117.644 1.00 113.42 ? 629 TYR B CA  1 
ATOM   7246 C C   . TYR B 2 640 ? 84.358  109.607 118.453 1.00 113.42 ? 629 TYR B C   1 
ATOM   7247 O O   . TYR B 2 640 ? 85.402  110.251 118.600 1.00 113.42 ? 629 TYR B O   1 
ATOM   7248 C CB  . TYR B 2 640 ? 85.425  107.359 118.154 1.00 113.42 ? 629 TYR B CB  1 
ATOM   7249 C CG  . TYR B 2 640 ? 85.344  107.072 119.638 1.00 113.42 ? 629 TYR B CG  1 
ATOM   7250 C CD1 . TYR B 2 640 ? 84.180  106.574 120.205 1.00 113.42 ? 629 TYR B CD1 1 
ATOM   7251 C CD2 . TYR B 2 640 ? 86.432  107.294 120.469 1.00 113.42 ? 629 TYR B CD2 1 
ATOM   7252 C CE1 . TYR B 2 640 ? 84.101  106.309 121.557 1.00 113.42 ? 629 TYR B CE1 1 
ATOM   7253 C CE2 . TYR B 2 640 ? 86.361  107.032 121.822 1.00 113.42 ? 629 TYR B CE2 1 
ATOM   7254 C CZ  . TYR B 2 640 ? 85.193  106.539 122.359 1.00 113.42 ? 629 TYR B CZ  1 
ATOM   7255 O OH  . TYR B 2 640 ? 85.114  106.275 123.705 1.00 113.42 ? 629 TYR B OH  1 
ATOM   7256 N N   . ALA B 2 641 ? 83.196  109.979 118.982 1.00 119.12 ? 630 ALA B N   1 
ATOM   7257 C CA  . ALA B 2 641 ? 83.044  111.182 119.785 1.00 119.12 ? 630 ALA B CA  1 
ATOM   7258 C C   . ALA B 2 641 ? 82.931  110.799 121.254 1.00 119.12 ? 630 ALA B C   1 
ATOM   7259 O O   . ALA B 2 641 ? 82.663  109.646 121.602 1.00 119.12 ? 630 ALA B O   1 
ATOM   7260 C CB  . ALA B 2 641 ? 81.820  111.998 119.349 1.00 119.12 ? 630 ALA B CB  1 
ATOM   7261 N N   . ALA B 2 642 ? 83.139  111.786 122.120 1.00 124.56 ? 631 ALA B N   1 
ATOM   7262 C CA  . ALA B 2 642 ? 83.070  111.570 123.561 1.00 124.56 ? 631 ALA B CA  1 
ATOM   7263 C C   . ALA B 2 642 ? 82.127  112.570 124.223 1.00 124.56 ? 631 ALA B C   1 
ATOM   7264 O O   . ALA B 2 642 ? 81.898  112.515 125.431 1.00 124.56 ? 631 ALA B O   1 
ATOM   7265 C CB  . ALA B 2 642 ? 84.457  111.660 124.178 1.00 124.56 ? 631 ALA B CB  1 
HETATM 7266 N N   . ARG C 3 .   ? 112.545 104.274 103.262 1.00 53.26  ? 601 ARG A N   1 
HETATM 7267 C CA  . ARG C 3 .   ? 112.825 103.974 104.641 1.00 53.26  ? 601 ARG A CA  1 
HETATM 7268 C C   . ARG C 3 .   ? 111.756 103.094 105.103 1.00 53.26  ? 601 ARG A C   1 
HETATM 7269 O O   . ARG C 3 .   ? 111.253 103.236 106.195 1.00 53.26  ? 601 ARG A O   1 
HETATM 7270 C CB  . ARG C 3 .   ? 112.843 105.231 105.486 1.00 53.26  ? 601 ARG A CB  1 
HETATM 7271 C CG  . ARG C 3 .   ? 114.208 105.689 105.947 1.00 53.26  ? 601 ARG A CG  1 
HETATM 7272 C CD  . ARG C 3 .   ? 114.446 107.144 105.600 1.00 53.26  ? 601 ARG A CD  1 
HETATM 7273 N NE  . ARG C 3 .   ? 115.752 107.596 106.063 1.00 53.26  ? 601 ARG A NE  1 
HETATM 7274 C CZ  . ARG C 3 .   ? 116.808 107.777 105.278 1.00 53.26  ? 601 ARG A CZ  1 
HETATM 7275 N NH1 . ARG C 3 .   ? 117.955 108.195 105.795 1.00 53.26  ? 601 ARG A NH1 1 
HETATM 7276 N NH2 . ARG C 3 .   ? 116.718 107.538 103.980 1.00 53.26  ? 601 ARG A NH2 1 
HETATM 7277 O OXT . ARG C 3 .   ? 111.393 102.220 104.377 1.00 53.26  ? 601 ARG A OXT 1 
# 
