data_9KSN
# 
_entry.id   9KSN 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9KSN         pdb_00009ksn 10.2210/pdb9ksn/pdb 
WWPDB D_1300053870 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-05-21 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9KSN 
_pdbx_database_status.recvd_initial_deposition_date   2024-11-30 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              zjzhang@ecust.edu.cn 
_pdbx_contact_author.name_first         Zhi-Jun 
_pdbx_contact_author.name_last          Zhang 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-9836-0204 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Wei, Y.'      1 ? 
'Geng, Q.'     2 ? 
'Zheng, Y.-C.' 3 ? 
'Zhang, Z.-J.' 4 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Acs Catalysis' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2155-5435 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                7720 
_citation.page_last                 7730 
_citation.title                     
'An Engineered meso-Diaminopimelate Dehydrogenase Enables the Biocatalytic Synthesis of Bulky beta-Substituted d-Amino Acids' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1021/acscatal.5c01214 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Wei, Y.'     1 ? 
primary 'Zheng, Y.C.' 2 ? 
primary 'Liu, H.P.'   3 ? 
primary 'Geng, Q.'    4 ? 
primary 'Wang, Z.'    5 ? 
primary 'Wang, Y.Q.'  6 ? 
primary 'Yu, H.L.'    7 ? 
primary 'Xu, J.H.'    8 ? 
primary 'Zhang, Z.J.' 9 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Meso-diaminopimelate D-dehydrogenase'             38187.918 3  1.4.1.16 ? ? ? 
2 non-polymer syn 'NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE' 743.405   3  ?        ? ? ? 
3 non-polymer syn 'OXAMIC ACID'                                      89.050    4  ?        ? ? ? 
4 non-polymer syn IMIDAZOLE                                          69.085    6  ?        ? ? ? 
5 non-polymer syn 'ACETIC ACID'                                      60.052    2  ?        ? ? ? 
6 water       nat water                                              18.015    45 ?        ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'DAPDH,Meso-DAP dehydrogenase' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MGSSHHHHHHSGIVPRGSHMASMTGGGQMGRGSEFELRRQMSEIRTERPIRVAIIGYGNIGQYALQAVEEAPDMELAGVV
RRQSSLEKPLPRELHGVSVVSDVSALGQVDVAVLCTPTYETPAIAKELLARGIHTIDSFDIHQEIVQVRHELDEVARAHQ
AVAILAAGLLPGTCSMIRSILEFMAPYGITYTNVGPGMSMSASVAVKAIEGVKDALALIIPIGTGLHRRMVYVELEEGAD
FATVKERILQDPLFVHDETHVLQVDDVKQLIDRGIAVRMERKGVSGQTQNQLFTYEMRINNPALTSQVMIASARAAMRQK
PGAYTMIEIPIIDFLYGDRDELIRRLV
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MGSSHHHHHHSGIVPRGSHMASMTGGGQMGRGSEFELRRQMSEIRTERPIRVAIIGYGNIGQYALQAVEEAPDMELAGVV
RRQSSLEKPLPRELHGVSVVSDVSALGQVDVAVLCTPTYETPAIAKELLARGIHTIDSFDIHQEIVQVRHELDEVARAHQ
AVAILAAGLLPGTCSMIRSILEFMAPYGITYTNVGPGMSMSASVAVKAIEGVKDALALIIPIGTGLHRRMVYVELEEGAD
FATVKERILQDPLFVHDETHVLQVDDVKQLIDRGIAVRMERKGVSGQTQNQLFTYEMRINNPALTSQVMIASARAAMRQK
PGAYTMIEIPIIDFLYGDRDELIRRLV
;
_entity_poly.pdbx_strand_id                 A,B,C 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE' NAP 
3 'OXAMIC ACID'                                      OXM 
4 IMIDAZOLE                                          IMD 
5 'ACETIC ACID'                                      ACY 
6 water                                              HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLY n 
1 3   SER n 
1 4   SER n 
1 5   HIS n 
1 6   HIS n 
1 7   HIS n 
1 8   HIS n 
1 9   HIS n 
1 10  HIS n 
1 11  SER n 
1 12  GLY n 
1 13  ILE n 
1 14  VAL n 
1 15  PRO n 
1 16  ARG n 
1 17  GLY n 
1 18  SER n 
1 19  HIS n 
1 20  MET n 
1 21  ALA n 
1 22  SER n 
1 23  MET n 
1 24  THR n 
1 25  GLY n 
1 26  GLY n 
1 27  GLY n 
1 28  GLN n 
1 29  MET n 
1 30  GLY n 
1 31  ARG n 
1 32  GLY n 
1 33  SER n 
1 34  GLU n 
1 35  PHE n 
1 36  GLU n 
1 37  LEU n 
1 38  ARG n 
1 39  ARG n 
1 40  GLN n 
1 41  MET n 
1 42  SER n 
1 43  GLU n 
1 44  ILE n 
1 45  ARG n 
1 46  THR n 
1 47  GLU n 
1 48  ARG n 
1 49  PRO n 
1 50  ILE n 
1 51  ARG n 
1 52  VAL n 
1 53  ALA n 
1 54  ILE n 
1 55  ILE n 
1 56  GLY n 
1 57  TYR n 
1 58  GLY n 
1 59  ASN n 
1 60  ILE n 
1 61  GLY n 
1 62  GLN n 
1 63  TYR n 
1 64  ALA n 
1 65  LEU n 
1 66  GLN n 
1 67  ALA n 
1 68  VAL n 
1 69  GLU n 
1 70  GLU n 
1 71  ALA n 
1 72  PRO n 
1 73  ASP n 
1 74  MET n 
1 75  GLU n 
1 76  LEU n 
1 77  ALA n 
1 78  GLY n 
1 79  VAL n 
1 80  VAL n 
1 81  ARG n 
1 82  ARG n 
1 83  GLN n 
1 84  SER n 
1 85  SER n 
1 86  LEU n 
1 87  GLU n 
1 88  LYS n 
1 89  PRO n 
1 90  LEU n 
1 91  PRO n 
1 92  ARG n 
1 93  GLU n 
1 94  LEU n 
1 95  HIS n 
1 96  GLY n 
1 97  VAL n 
1 98  SER n 
1 99  VAL n 
1 100 VAL n 
1 101 SER n 
1 102 ASP n 
1 103 VAL n 
1 104 SER n 
1 105 ALA n 
1 106 LEU n 
1 107 GLY n 
1 108 GLN n 
1 109 VAL n 
1 110 ASP n 
1 111 VAL n 
1 112 ALA n 
1 113 VAL n 
1 114 LEU n 
1 115 CYS n 
1 116 THR n 
1 117 PRO n 
1 118 THR n 
1 119 TYR n 
1 120 GLU n 
1 121 THR n 
1 122 PRO n 
1 123 ALA n 
1 124 ILE n 
1 125 ALA n 
1 126 LYS n 
1 127 GLU n 
1 128 LEU n 
1 129 LEU n 
1 130 ALA n 
1 131 ARG n 
1 132 GLY n 
1 133 ILE n 
1 134 HIS n 
1 135 THR n 
1 136 ILE n 
1 137 ASP n 
1 138 SER n 
1 139 PHE n 
1 140 ASP n 
1 141 ILE n 
1 142 HIS n 
1 143 GLN n 
1 144 GLU n 
1 145 ILE n 
1 146 VAL n 
1 147 GLN n 
1 148 VAL n 
1 149 ARG n 
1 150 HIS n 
1 151 GLU n 
1 152 LEU n 
1 153 ASP n 
1 154 GLU n 
1 155 VAL n 
1 156 ALA n 
1 157 ARG n 
1 158 ALA n 
1 159 HIS n 
1 160 GLN n 
1 161 ALA n 
1 162 VAL n 
1 163 ALA n 
1 164 ILE n 
1 165 LEU n 
1 166 ALA n 
1 167 ALA n 
1 168 GLY n 
1 169 LEU n 
1 170 LEU n 
1 171 PRO n 
1 172 GLY n 
1 173 THR n 
1 174 CYS n 
1 175 SER n 
1 176 MET n 
1 177 ILE n 
1 178 ARG n 
1 179 SER n 
1 180 ILE n 
1 181 LEU n 
1 182 GLU n 
1 183 PHE n 
1 184 MET n 
1 185 ALA n 
1 186 PRO n 
1 187 TYR n 
1 188 GLY n 
1 189 ILE n 
1 190 THR n 
1 191 TYR n 
1 192 THR n 
1 193 ASN n 
1 194 VAL n 
1 195 GLY n 
1 196 PRO n 
1 197 GLY n 
1 198 MET n 
1 199 SER n 
1 200 MET n 
1 201 SER n 
1 202 ALA n 
1 203 SER n 
1 204 VAL n 
1 205 ALA n 
1 206 VAL n 
1 207 LYS n 
1 208 ALA n 
1 209 ILE n 
1 210 GLU n 
1 211 GLY n 
1 212 VAL n 
1 213 LYS n 
1 214 ASP n 
1 215 ALA n 
1 216 LEU n 
1 217 ALA n 
1 218 LEU n 
1 219 ILE n 
1 220 ILE n 
1 221 PRO n 
1 222 ILE n 
1 223 GLY n 
1 224 THR n 
1 225 GLY n 
1 226 LEU n 
1 227 HIS n 
1 228 ARG n 
1 229 ARG n 
1 230 MET n 
1 231 VAL n 
1 232 TYR n 
1 233 VAL n 
1 234 GLU n 
1 235 LEU n 
1 236 GLU n 
1 237 GLU n 
1 238 GLY n 
1 239 ALA n 
1 240 ASP n 
1 241 PHE n 
1 242 ALA n 
1 243 THR n 
1 244 VAL n 
1 245 LYS n 
1 246 GLU n 
1 247 ARG n 
1 248 ILE n 
1 249 LEU n 
1 250 GLN n 
1 251 ASP n 
1 252 PRO n 
1 253 LEU n 
1 254 PHE n 
1 255 VAL n 
1 256 HIS n 
1 257 ASP n 
1 258 GLU n 
1 259 THR n 
1 260 HIS n 
1 261 VAL n 
1 262 LEU n 
1 263 GLN n 
1 264 VAL n 
1 265 ASP n 
1 266 ASP n 
1 267 VAL n 
1 268 LYS n 
1 269 GLN n 
1 270 LEU n 
1 271 ILE n 
1 272 ASP n 
1 273 ARG n 
1 274 GLY n 
1 275 ILE n 
1 276 ALA n 
1 277 VAL n 
1 278 ARG n 
1 279 MET n 
1 280 GLU n 
1 281 ARG n 
1 282 LYS n 
1 283 GLY n 
1 284 VAL n 
1 285 SER n 
1 286 GLY n 
1 287 GLN n 
1 288 THR n 
1 289 GLN n 
1 290 ASN n 
1 291 GLN n 
1 292 LEU n 
1 293 PHE n 
1 294 THR n 
1 295 TYR n 
1 296 GLU n 
1 297 MET n 
1 298 ARG n 
1 299 ILE n 
1 300 ASN n 
1 301 ASN n 
1 302 PRO n 
1 303 ALA n 
1 304 LEU n 
1 305 THR n 
1 306 SER n 
1 307 GLN n 
1 308 VAL n 
1 309 MET n 
1 310 ILE n 
1 311 ALA n 
1 312 SER n 
1 313 ALA n 
1 314 ARG n 
1 315 ALA n 
1 316 ALA n 
1 317 MET n 
1 318 ARG n 
1 319 GLN n 
1 320 LYS n 
1 321 PRO n 
1 322 GLY n 
1 323 ALA n 
1 324 TYR n 
1 325 THR n 
1 326 MET n 
1 327 ILE n 
1 328 GLU n 
1 329 ILE n 
1 330 PRO n 
1 331 ILE n 
1 332 ILE n 
1 333 ASP n 
1 334 PHE n 
1 335 LEU n 
1 336 TYR n 
1 337 GLY n 
1 338 ASP n 
1 339 ARG n 
1 340 ASP n 
1 341 GLU n 
1 342 LEU n 
1 343 ILE n 
1 344 ARG n 
1 345 ARG n 
1 346 LEU n 
1 347 VAL n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   347 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 BAA01_00405 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Bacillus thermozeamaize' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     230954 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ACY non-polymer         . 'ACETIC ACID'                                      ?                                            
'C2 H4 O2'          60.052  
ALA 'L-peptide linking' y ALANINE                                            ?                                            
'C3 H7 N O2'        89.093  
ARG 'L-peptide linking' y ARGININE                                           ?                                            
'C6 H15 N4 O2 1'    175.209 
ASN 'L-peptide linking' y ASPARAGINE                                         ?                                            
'C4 H8 N2 O3'       132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                                    ?                                            
'C4 H7 N O4'        133.103 
CYS 'L-peptide linking' y CYSTEINE                                           ?                                            
'C3 H7 N O2 S'      121.158 
GLN 'L-peptide linking' y GLUTAMINE                                          ?                                            
'C5 H10 N2 O3'      146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                                    ?                                            
'C5 H9 N O4'        147.129 
GLY 'peptide linking'   y GLYCINE                                            ?                                            
'C2 H5 N O2'        75.067  
HIS 'L-peptide linking' y HISTIDINE                                          ?                                            
'C6 H10 N3 O2 1'    156.162 
HOH non-polymer         . WATER                                              ?                                            'H2 O' 
18.015  
ILE 'L-peptide linking' y ISOLEUCINE                                         ?                                            
'C6 H13 N O2'       131.173 
IMD non-polymer         . IMIDAZOLE                                          ?                                            
'C3 H5 N2 1'        69.085  
LEU 'L-peptide linking' y LEUCINE                                            ?                                            
'C6 H13 N O2'       131.173 
LYS 'L-peptide linking' y LYSINE                                             ?                                            
'C6 H15 N2 O2 1'    147.195 
MET 'L-peptide linking' y METHIONINE                                         ?                                            
'C5 H11 N O2 S'     149.211 
NAP non-polymer         . 'NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE' 
;2'-MONOPHOSPHOADENOSINE 5'-DIPHOSPHORIBOSE
;
'C21 H28 N7 O17 P3' 743.405 
OXM non-polymer         . 'OXAMIC ACID'                                      ?                                            
'C2 H3 N O3'        89.050  
PHE 'L-peptide linking' y PHENYLALANINE                                      ?                                            
'C9 H11 N O2'       165.189 
PRO 'L-peptide linking' y PROLINE                                            ?                                            
'C5 H9 N O2'        115.130 
SER 'L-peptide linking' y SERINE                                             ?                                            
'C3 H7 N O3'        105.093 
THR 'L-peptide linking' y THREONINE                                          ?                                            
'C4 H9 N O3'        119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                                         ?                                            
'C11 H12 N2 O2'     204.225 
TYR 'L-peptide linking' y TYROSINE                                           ?                                            
'C9 H11 N O3'       181.189 
VAL 'L-peptide linking' y VALINE                                             ?                                            
'C5 H11 N O2'       117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   -39 ?   ?   ?   A . n 
A 1 2   GLY 2   -38 ?   ?   ?   A . n 
A 1 3   SER 3   -37 ?   ?   ?   A . n 
A 1 4   SER 4   -36 ?   ?   ?   A . n 
A 1 5   HIS 5   -35 ?   ?   ?   A . n 
A 1 6   HIS 6   -34 ?   ?   ?   A . n 
A 1 7   HIS 7   -33 ?   ?   ?   A . n 
A 1 8   HIS 8   -32 ?   ?   ?   A . n 
A 1 9   HIS 9   -31 ?   ?   ?   A . n 
A 1 10  HIS 10  -30 ?   ?   ?   A . n 
A 1 11  SER 11  -29 ?   ?   ?   A . n 
A 1 12  GLY 12  -28 ?   ?   ?   A . n 
A 1 13  ILE 13  -27 ?   ?   ?   A . n 
A 1 14  VAL 14  -26 ?   ?   ?   A . n 
A 1 15  PRO 15  -25 ?   ?   ?   A . n 
A 1 16  ARG 16  -24 ?   ?   ?   A . n 
A 1 17  GLY 17  -23 ?   ?   ?   A . n 
A 1 18  SER 18  -22 ?   ?   ?   A . n 
A 1 19  HIS 19  -21 ?   ?   ?   A . n 
A 1 20  MET 20  -20 ?   ?   ?   A . n 
A 1 21  ALA 21  -19 ?   ?   ?   A . n 
A 1 22  SER 22  -18 ?   ?   ?   A . n 
A 1 23  MET 23  -17 ?   ?   ?   A . n 
A 1 24  THR 24  -16 ?   ?   ?   A . n 
A 1 25  GLY 25  -15 ?   ?   ?   A . n 
A 1 26  GLY 26  -14 ?   ?   ?   A . n 
A 1 27  GLY 27  -13 ?   ?   ?   A . n 
A 1 28  GLN 28  -12 ?   ?   ?   A . n 
A 1 29  MET 29  -11 ?   ?   ?   A . n 
A 1 30  GLY 30  -10 ?   ?   ?   A . n 
A 1 31  ARG 31  -9  ?   ?   ?   A . n 
A 1 32  GLY 32  -8  ?   ?   ?   A . n 
A 1 33  SER 33  -7  ?   ?   ?   A . n 
A 1 34  GLU 34  -6  ?   ?   ?   A . n 
A 1 35  PHE 35  -5  ?   ?   ?   A . n 
A 1 36  GLU 36  -4  ?   ?   ?   A . n 
A 1 37  LEU 37  -3  ?   ?   ?   A . n 
A 1 38  ARG 38  -2  ?   ?   ?   A . n 
A 1 39  ARG 39  -1  ?   ?   ?   A . n 
A 1 40  GLN 40  0   ?   ?   ?   A . n 
A 1 41  MET 41  1   ?   ?   ?   A . n 
A 1 42  SER 42  2   ?   ?   ?   A . n 
A 1 43  GLU 43  3   ?   ?   ?   A . n 
A 1 44  ILE 44  4   ?   ?   ?   A . n 
A 1 45  ARG 45  5   5   ARG ARG A . n 
A 1 46  THR 46  6   6   THR THR A . n 
A 1 47  GLU 47  7   7   GLU GLU A . n 
A 1 48  ARG 48  8   8   ARG ARG A . n 
A 1 49  PRO 49  9   9   PRO PRO A . n 
A 1 50  ILE 50  10  10  ILE ILE A . n 
A 1 51  ARG 51  11  11  ARG ARG A . n 
A 1 52  VAL 52  12  12  VAL VAL A . n 
A 1 53  ALA 53  13  13  ALA ALA A . n 
A 1 54  ILE 54  14  14  ILE ILE A . n 
A 1 55  ILE 55  15  15  ILE ILE A . n 
A 1 56  GLY 56  16  16  GLY GLY A . n 
A 1 57  TYR 57  17  17  TYR TYR A . n 
A 1 58  GLY 58  18  18  GLY GLY A . n 
A 1 59  ASN 59  19  19  ASN ASN A . n 
A 1 60  ILE 60  20  20  ILE ILE A . n 
A 1 61  GLY 61  21  21  GLY GLY A . n 
A 1 62  GLN 62  22  22  GLN GLN A . n 
A 1 63  TYR 63  23  23  TYR TYR A . n 
A 1 64  ALA 64  24  24  ALA ALA A . n 
A 1 65  LEU 65  25  25  LEU LEU A . n 
A 1 66  GLN 66  26  26  GLN GLN A . n 
A 1 67  ALA 67  27  27  ALA ALA A . n 
A 1 68  VAL 68  28  28  VAL VAL A . n 
A 1 69  GLU 69  29  29  GLU GLU A . n 
A 1 70  GLU 70  30  30  GLU GLU A . n 
A 1 71  ALA 71  31  31  ALA ALA A . n 
A 1 72  PRO 72  32  32  PRO PRO A . n 
A 1 73  ASP 73  33  33  ASP ASP A . n 
A 1 74  MET 74  34  34  MET MET A . n 
A 1 75  GLU 75  35  35  GLU GLU A . n 
A 1 76  LEU 76  36  36  LEU LEU A . n 
A 1 77  ALA 77  37  37  ALA ALA A . n 
A 1 78  GLY 78  38  38  GLY GLY A . n 
A 1 79  VAL 79  39  39  VAL VAL A . n 
A 1 80  VAL 80  40  40  VAL VAL A . n 
A 1 81  ARG 81  41  41  ARG ARG A . n 
A 1 82  ARG 82  42  42  ARG ARG A . n 
A 1 83  GLN 83  43  43  GLN GLN A . n 
A 1 84  SER 84  44  44  SER SER A . n 
A 1 85  SER 85  45  45  SER SER A . n 
A 1 86  LEU 86  46  46  LEU LEU A . n 
A 1 87  GLU 87  47  47  GLU GLU A . n 
A 1 88  LYS 88  48  48  LYS LYS A . n 
A 1 89  PRO 89  49  49  PRO PRO A . n 
A 1 90  LEU 90  50  50  LEU LEU A . n 
A 1 91  PRO 91  51  51  PRO PRO A . n 
A 1 92  ARG 92  52  52  ARG ARG A . n 
A 1 93  GLU 93  53  53  GLU GLU A . n 
A 1 94  LEU 94  54  54  LEU LEU A . n 
A 1 95  HIS 95  55  55  HIS HIS A . n 
A 1 96  GLY 96  56  56  GLY GLY A . n 
A 1 97  VAL 97  57  57  VAL VAL A . n 
A 1 98  SER 98  58  58  SER SER A . n 
A 1 99  VAL 99  59  59  VAL VAL A . n 
A 1 100 VAL 100 60  60  VAL VAL A . n 
A 1 101 SER 101 61  61  SER SER A . n 
A 1 102 ASP 102 62  62  ASP ASP A . n 
A 1 103 VAL 103 63  63  VAL VAL A . n 
A 1 104 SER 104 64  64  SER SER A . n 
A 1 105 ALA 105 65  65  ALA ALA A . n 
A 1 106 LEU 106 66  66  LEU LEU A . n 
A 1 107 GLY 107 67  67  GLY GLY A . n 
A 1 108 GLN 108 68  68  GLN GLN A . n 
A 1 109 VAL 109 69  69  VAL VAL A . n 
A 1 110 ASP 110 70  70  ASP ASP A . n 
A 1 111 VAL 111 71  71  VAL VAL A . n 
A 1 112 ALA 112 72  72  ALA ALA A . n 
A 1 113 VAL 113 73  73  VAL VAL A . n 
A 1 114 LEU 114 74  74  LEU LEU A . n 
A 1 115 CYS 115 75  75  CYS CYS A . n 
A 1 116 THR 116 76  76  THR THR A . n 
A 1 117 PRO 117 77  77  PRO PRO A . n 
A 1 118 THR 118 78  78  THR THR A . n 
A 1 119 TYR 119 79  79  TYR TYR A . n 
A 1 120 GLU 120 80  80  GLU GLU A . n 
A 1 121 THR 121 81  81  THR THR A . n 
A 1 122 PRO 122 82  82  PRO PRO A . n 
A 1 123 ALA 123 83  83  ALA ALA A . n 
A 1 124 ILE 124 84  84  ILE ILE A . n 
A 1 125 ALA 125 85  85  ALA ALA A . n 
A 1 126 LYS 126 86  86  LYS LYS A . n 
A 1 127 GLU 127 87  87  GLU GLU A . n 
A 1 128 LEU 128 88  88  LEU LEU A . n 
A 1 129 LEU 129 89  89  LEU LEU A . n 
A 1 130 ALA 130 90  90  ALA ALA A . n 
A 1 131 ARG 131 91  91  ARG ARG A . n 
A 1 132 GLY 132 92  92  GLY GLY A . n 
A 1 133 ILE 133 93  93  ILE ILE A . n 
A 1 134 HIS 134 94  94  HIS HIS A . n 
A 1 135 THR 135 95  95  THR THR A . n 
A 1 136 ILE 136 96  96  ILE ILE A . n 
A 1 137 ASP 137 97  97  ASP ASP A . n 
A 1 138 SER 138 98  98  SER SER A . n 
A 1 139 PHE 139 99  99  PHE PHE A . n 
A 1 140 ASP 140 100 100 ASP ASP A . n 
A 1 141 ILE 141 101 101 ILE ILE A . n 
A 1 142 HIS 142 102 102 HIS HIS A . n 
A 1 143 GLN 143 103 103 GLN GLN A . n 
A 1 144 GLU 144 104 104 GLU GLU A . n 
A 1 145 ILE 145 105 105 ILE ILE A . n 
A 1 146 VAL 146 106 106 VAL VAL A . n 
A 1 147 GLN 147 107 107 GLN GLN A . n 
A 1 148 VAL 148 108 108 VAL VAL A . n 
A 1 149 ARG 149 109 109 ARG ARG A . n 
A 1 150 HIS 150 110 110 HIS HIS A . n 
A 1 151 GLU 151 111 111 GLU GLU A . n 
A 1 152 LEU 152 112 112 LEU LEU A . n 
A 1 153 ASP 153 113 113 ASP ASP A . n 
A 1 154 GLU 154 114 114 GLU GLU A . n 
A 1 155 VAL 155 115 115 VAL VAL A . n 
A 1 156 ALA 156 116 116 ALA ALA A . n 
A 1 157 ARG 157 117 117 ARG ARG A . n 
A 1 158 ALA 158 118 118 ALA ALA A . n 
A 1 159 HIS 159 119 119 HIS HIS A . n 
A 1 160 GLN 160 120 120 GLN GLN A . n 
A 1 161 ALA 161 121 121 ALA ALA A . n 
A 1 162 VAL 162 122 122 VAL VAL A . n 
A 1 163 ALA 163 123 123 ALA ALA A . n 
A 1 164 ILE 164 124 124 ILE ILE A . n 
A 1 165 LEU 165 125 125 LEU LEU A . n 
A 1 166 ALA 166 126 126 ALA ALA A . n 
A 1 167 ALA 167 127 127 ALA ALA A . n 
A 1 168 GLY 168 128 128 GLY GLY A . n 
A 1 169 LEU 169 129 129 LEU LEU A . n 
A 1 170 LEU 170 130 130 LEU LEU A . n 
A 1 171 PRO 171 131 131 PRO PRO A . n 
A 1 172 GLY 172 132 132 GLY GLY A . n 
A 1 173 THR 173 133 133 THR THR A . n 
A 1 174 CYS 174 134 134 CYS CYS A . n 
A 1 175 SER 175 135 135 SER SER A . n 
A 1 176 MET 176 136 136 MET MET A . n 
A 1 177 ILE 177 137 137 ILE ILE A . n 
A 1 178 ARG 178 138 138 ARG ARG A . n 
A 1 179 SER 179 139 139 SER SER A . n 
A 1 180 ILE 180 140 140 ILE ILE A . n 
A 1 181 LEU 181 141 141 LEU LEU A . n 
A 1 182 GLU 182 142 142 GLU GLU A . n 
A 1 183 PHE 183 143 143 PHE PHE A . n 
A 1 184 MET 184 144 144 MET MET A . n 
A 1 185 ALA 185 145 145 ALA ALA A . n 
A 1 186 PRO 186 146 146 PRO PRO A . n 
A 1 187 TYR 187 147 147 TYR TYR A . n 
A 1 188 GLY 188 148 148 GLY GLY A . n 
A 1 189 ILE 189 149 149 ILE ILE A . n 
A 1 190 THR 190 150 150 THR THR A . n 
A 1 191 TYR 191 151 151 TYR TYR A . n 
A 1 192 THR 192 152 152 THR THR A . n 
A 1 193 ASN 193 153 153 ASN ASN A . n 
A 1 194 VAL 194 154 154 VAL VAL A . n 
A 1 195 GLY 195 155 155 GLY GLY A . n 
A 1 196 PRO 196 156 156 PRO PRO A . n 
A 1 197 GLY 197 157 157 GLY GLY A . n 
A 1 198 MET 198 158 158 MET MET A . n 
A 1 199 SER 199 159 159 SER SER A . n 
A 1 200 MET 200 160 160 MET MET A . n 
A 1 201 SER 201 161 161 SER SER A . n 
A 1 202 ALA 202 162 162 ALA ALA A . n 
A 1 203 SER 203 163 163 SER SER A . n 
A 1 204 VAL 204 164 164 VAL VAL A . n 
A 1 205 ALA 205 165 165 ALA ALA A . n 
A 1 206 VAL 206 166 166 VAL VAL A . n 
A 1 207 LYS 207 167 167 LYS LYS A . n 
A 1 208 ALA 208 168 168 ALA ALA A . n 
A 1 209 ILE 209 169 169 ILE ILE A . n 
A 1 210 GLU 210 170 170 GLU GLU A . n 
A 1 211 GLY 211 171 171 GLY GLY A . n 
A 1 212 VAL 212 172 172 VAL VAL A . n 
A 1 213 LYS 213 173 173 LYS LYS A . n 
A 1 214 ASP 214 174 174 ASP ASP A . n 
A 1 215 ALA 215 175 175 ALA ALA A . n 
A 1 216 LEU 216 176 176 LEU LEU A . n 
A 1 217 ALA 217 177 177 ALA ALA A . n 
A 1 218 LEU 218 178 178 LEU LEU A . n 
A 1 219 ILE 219 179 179 ILE ILE A . n 
A 1 220 ILE 220 180 180 ILE ILE A . n 
A 1 221 PRO 221 181 181 PRO PRO A . n 
A 1 222 ILE 222 182 182 ILE ILE A . n 
A 1 223 GLY 223 183 183 GLY GLY A . n 
A 1 224 THR 224 184 184 THR THR A . n 
A 1 225 GLY 225 185 185 GLY GLY A . n 
A 1 226 LEU 226 186 186 LEU LEU A . n 
A 1 227 HIS 227 187 187 HIS HIS A . n 
A 1 228 ARG 228 188 188 ARG ARG A . n 
A 1 229 ARG 229 189 189 ARG ARG A . n 
A 1 230 MET 230 190 190 MET MET A . n 
A 1 231 VAL 231 191 191 VAL VAL A . n 
A 1 232 TYR 232 192 192 TYR TYR A . n 
A 1 233 VAL 233 193 193 VAL VAL A . n 
A 1 234 GLU 234 194 194 GLU GLU A . n 
A 1 235 LEU 235 195 195 LEU LEU A . n 
A 1 236 GLU 236 196 196 GLU GLU A . n 
A 1 237 GLU 237 197 197 GLU GLU A . n 
A 1 238 GLY 238 198 198 GLY GLY A . n 
A 1 239 ALA 239 199 199 ALA ALA A . n 
A 1 240 ASP 240 200 200 ASP ASP A . n 
A 1 241 PHE 241 201 201 PHE PHE A . n 
A 1 242 ALA 242 202 202 ALA ALA A . n 
A 1 243 THR 243 203 203 THR THR A . n 
A 1 244 VAL 244 204 204 VAL VAL A . n 
A 1 245 LYS 245 205 205 LYS LYS A . n 
A 1 246 GLU 246 206 206 GLU GLU A . n 
A 1 247 ARG 247 207 207 ARG ARG A . n 
A 1 248 ILE 248 208 208 ILE ILE A . n 
A 1 249 LEU 249 209 209 LEU LEU A . n 
A 1 250 GLN 250 210 210 GLN GLN A . n 
A 1 251 ASP 251 211 211 ASP ASP A . n 
A 1 252 PRO 252 212 212 PRO PRO A . n 
A 1 253 LEU 253 213 213 LEU LEU A . n 
A 1 254 PHE 254 214 214 PHE PHE A . n 
A 1 255 VAL 255 215 215 VAL VAL A . n 
A 1 256 HIS 256 216 216 HIS HIS A . n 
A 1 257 ASP 257 217 217 ASP ASP A . n 
A 1 258 GLU 258 218 218 GLU GLU A . n 
A 1 259 THR 259 219 219 THR THR A . n 
A 1 260 HIS 260 220 220 HIS HIS A . n 
A 1 261 VAL 261 221 221 VAL VAL A . n 
A 1 262 LEU 262 222 222 LEU LEU A . n 
A 1 263 GLN 263 223 223 GLN GLN A . n 
A 1 264 VAL 264 224 224 VAL VAL A . n 
A 1 265 ASP 265 225 225 ASP ASP A . n 
A 1 266 ASP 266 226 226 ASP ASP A . n 
A 1 267 VAL 267 227 227 VAL VAL A . n 
A 1 268 LYS 268 228 228 LYS LYS A . n 
A 1 269 GLN 269 229 229 GLN GLN A . n 
A 1 270 LEU 270 230 230 LEU LEU A . n 
A 1 271 ILE 271 231 231 ILE ILE A . n 
A 1 272 ASP 272 232 232 ASP ASP A . n 
A 1 273 ARG 273 233 233 ARG ARG A . n 
A 1 274 GLY 274 234 234 GLY GLY A . n 
A 1 275 ILE 275 235 235 ILE ILE A . n 
A 1 276 ALA 276 236 236 ALA ALA A . n 
A 1 277 VAL 277 237 237 VAL VAL A . n 
A 1 278 ARG 278 238 238 ARG ARG A . n 
A 1 279 MET 279 239 239 MET MET A . n 
A 1 280 GLU 280 240 240 GLU GLU A . n 
A 1 281 ARG 281 241 241 ARG ARG A . n 
A 1 282 LYS 282 242 242 LYS LYS A . n 
A 1 283 GLY 283 243 243 GLY GLY A . n 
A 1 284 VAL 284 244 244 VAL VAL A . n 
A 1 285 SER 285 245 245 SER SER A . n 
A 1 286 GLY 286 246 246 GLY GLY A . n 
A 1 287 GLN 287 247 247 GLN GLN A . n 
A 1 288 THR 288 248 248 THR THR A . n 
A 1 289 GLN 289 249 249 GLN GLN A . n 
A 1 290 ASN 290 250 250 ASN ASN A . n 
A 1 291 GLN 291 251 251 GLN GLN A . n 
A 1 292 LEU 292 252 252 LEU LEU A . n 
A 1 293 PHE 293 253 253 PHE PHE A . n 
A 1 294 THR 294 254 254 THR THR A . n 
A 1 295 TYR 295 255 255 TYR TYR A . n 
A 1 296 GLU 296 256 256 GLU GLU A . n 
A 1 297 MET 297 257 257 MET MET A . n 
A 1 298 ARG 298 258 258 ARG ARG A . n 
A 1 299 ILE 299 259 259 ILE ILE A . n 
A 1 300 ASN 300 260 260 ASN ASN A . n 
A 1 301 ASN 301 261 261 ASN ASN A . n 
A 1 302 PRO 302 262 262 PRO PRO A . n 
A 1 303 ALA 303 263 263 ALA ALA A . n 
A 1 304 LEU 304 264 264 LEU LEU A . n 
A 1 305 THR 305 265 265 THR THR A . n 
A 1 306 SER 306 266 266 SER SER A . n 
A 1 307 GLN 307 267 267 GLN GLN A . n 
A 1 308 VAL 308 268 268 VAL VAL A . n 
A 1 309 MET 309 269 269 MET MET A . n 
A 1 310 ILE 310 270 270 ILE ILE A . n 
A 1 311 ALA 311 271 271 ALA ALA A . n 
A 1 312 SER 312 272 272 SER SER A . n 
A 1 313 ALA 313 273 273 ALA ALA A . n 
A 1 314 ARG 314 274 274 ARG ARG A . n 
A 1 315 ALA 315 275 275 ALA ALA A . n 
A 1 316 ALA 316 276 276 ALA ALA A . n 
A 1 317 MET 317 277 277 MET MET A . n 
A 1 318 ARG 318 278 278 ARG ARG A . n 
A 1 319 GLN 319 279 279 GLN GLN A . n 
A 1 320 LYS 320 280 280 LYS LYS A . n 
A 1 321 PRO 321 281 281 PRO PRO A . n 
A 1 322 GLY 322 282 282 GLY GLY A . n 
A 1 323 ALA 323 283 283 ALA ALA A . n 
A 1 324 TYR 324 284 284 TYR TYR A . n 
A 1 325 THR 325 285 285 THR THR A . n 
A 1 326 MET 326 286 286 MET MET A . n 
A 1 327 ILE 327 287 287 ILE ILE A . n 
A 1 328 GLU 328 288 288 GLU GLU A . n 
A 1 329 ILE 329 289 289 ILE ILE A . n 
A 1 330 PRO 330 290 290 PRO PRO A . n 
A 1 331 ILE 331 291 291 ILE ILE A . n 
A 1 332 ILE 332 292 292 ILE ILE A . n 
A 1 333 ASP 333 293 293 ASP ASP A . n 
A 1 334 PHE 334 294 294 PHE PHE A . n 
A 1 335 LEU 335 295 295 LEU LEU A . n 
A 1 336 TYR 336 296 296 TYR TYR A . n 
A 1 337 GLY 337 297 297 GLY GLY A . n 
A 1 338 ASP 338 298 298 ASP ASP A . n 
A 1 339 ARG 339 299 299 ARG ARG A . n 
A 1 340 ASP 340 300 300 ASP ASP A . n 
A 1 341 GLU 341 301 301 GLU GLU A . n 
A 1 342 LEU 342 302 302 LEU LEU A . n 
A 1 343 ILE 343 303 303 ILE ILE A . n 
A 1 344 ARG 344 304 304 ARG ARG A . n 
A 1 345 ARG 345 305 305 ARG ARG A . n 
A 1 346 LEU 346 306 306 LEU LEU A . n 
A 1 347 VAL 347 307 307 VAL VAL A . n 
B 1 1   MET 1   -39 ?   ?   ?   B . n 
B 1 2   GLY 2   -38 ?   ?   ?   B . n 
B 1 3   SER 3   -37 ?   ?   ?   B . n 
B 1 4   SER 4   -36 ?   ?   ?   B . n 
B 1 5   HIS 5   -35 ?   ?   ?   B . n 
B 1 6   HIS 6   -34 ?   ?   ?   B . n 
B 1 7   HIS 7   -33 ?   ?   ?   B . n 
B 1 8   HIS 8   -32 ?   ?   ?   B . n 
B 1 9   HIS 9   -31 ?   ?   ?   B . n 
B 1 10  HIS 10  -30 ?   ?   ?   B . n 
B 1 11  SER 11  -29 ?   ?   ?   B . n 
B 1 12  GLY 12  -28 ?   ?   ?   B . n 
B 1 13  ILE 13  -27 ?   ?   ?   B . n 
B 1 14  VAL 14  -26 ?   ?   ?   B . n 
B 1 15  PRO 15  -25 ?   ?   ?   B . n 
B 1 16  ARG 16  -24 ?   ?   ?   B . n 
B 1 17  GLY 17  -23 ?   ?   ?   B . n 
B 1 18  SER 18  -22 ?   ?   ?   B . n 
B 1 19  HIS 19  -21 ?   ?   ?   B . n 
B 1 20  MET 20  -20 ?   ?   ?   B . n 
B 1 21  ALA 21  -19 ?   ?   ?   B . n 
B 1 22  SER 22  -18 ?   ?   ?   B . n 
B 1 23  MET 23  -17 ?   ?   ?   B . n 
B 1 24  THR 24  -16 ?   ?   ?   B . n 
B 1 25  GLY 25  -15 ?   ?   ?   B . n 
B 1 26  GLY 26  -14 ?   ?   ?   B . n 
B 1 27  GLY 27  -13 ?   ?   ?   B . n 
B 1 28  GLN 28  -12 ?   ?   ?   B . n 
B 1 29  MET 29  -11 ?   ?   ?   B . n 
B 1 30  GLY 30  -10 ?   ?   ?   B . n 
B 1 31  ARG 31  -9  ?   ?   ?   B . n 
B 1 32  GLY 32  -8  ?   ?   ?   B . n 
B 1 33  SER 33  -7  ?   ?   ?   B . n 
B 1 34  GLU 34  -6  ?   ?   ?   B . n 
B 1 35  PHE 35  -5  ?   ?   ?   B . n 
B 1 36  GLU 36  -4  ?   ?   ?   B . n 
B 1 37  LEU 37  -3  ?   ?   ?   B . n 
B 1 38  ARG 38  -2  ?   ?   ?   B . n 
B 1 39  ARG 39  -1  ?   ?   ?   B . n 
B 1 40  GLN 40  0   ?   ?   ?   B . n 
B 1 41  MET 41  1   ?   ?   ?   B . n 
B 1 42  SER 42  2   2   SER SER B . n 
B 1 43  GLU 43  3   3   GLU GLU B . n 
B 1 44  ILE 44  4   4   ILE ILE B . n 
B 1 45  ARG 45  5   5   ARG ARG B . n 
B 1 46  THR 46  6   6   THR THR B . n 
B 1 47  GLU 47  7   7   GLU GLU B . n 
B 1 48  ARG 48  8   8   ARG ARG B . n 
B 1 49  PRO 49  9   9   PRO PRO B . n 
B 1 50  ILE 50  10  10  ILE ILE B . n 
B 1 51  ARG 51  11  11  ARG ARG B . n 
B 1 52  VAL 52  12  12  VAL VAL B . n 
B 1 53  ALA 53  13  13  ALA ALA B . n 
B 1 54  ILE 54  14  14  ILE ILE B . n 
B 1 55  ILE 55  15  15  ILE ILE B . n 
B 1 56  GLY 56  16  16  GLY GLY B . n 
B 1 57  TYR 57  17  17  TYR TYR B . n 
B 1 58  GLY 58  18  18  GLY GLY B . n 
B 1 59  ASN 59  19  19  ASN ASN B . n 
B 1 60  ILE 60  20  20  ILE ILE B . n 
B 1 61  GLY 61  21  21  GLY GLY B . n 
B 1 62  GLN 62  22  22  GLN GLN B . n 
B 1 63  TYR 63  23  23  TYR TYR B . n 
B 1 64  ALA 64  24  24  ALA ALA B . n 
B 1 65  LEU 65  25  25  LEU LEU B . n 
B 1 66  GLN 66  26  26  GLN GLN B . n 
B 1 67  ALA 67  27  27  ALA ALA B . n 
B 1 68  VAL 68  28  28  VAL VAL B . n 
B 1 69  GLU 69  29  29  GLU GLU B . n 
B 1 70  GLU 70  30  30  GLU GLU B . n 
B 1 71  ALA 71  31  31  ALA ALA B . n 
B 1 72  PRO 72  32  32  PRO PRO B . n 
B 1 73  ASP 73  33  33  ASP ASP B . n 
B 1 74  MET 74  34  34  MET MET B . n 
B 1 75  GLU 75  35  35  GLU GLU B . n 
B 1 76  LEU 76  36  36  LEU LEU B . n 
B 1 77  ALA 77  37  37  ALA ALA B . n 
B 1 78  GLY 78  38  38  GLY GLY B . n 
B 1 79  VAL 79  39  39  VAL VAL B . n 
B 1 80  VAL 80  40  40  VAL VAL B . n 
B 1 81  ARG 81  41  41  ARG ARG B . n 
B 1 82  ARG 82  42  42  ARG ARG B . n 
B 1 83  GLN 83  43  43  GLN GLN B . n 
B 1 84  SER 84  44  44  SER SER B . n 
B 1 85  SER 85  45  45  SER SER B . n 
B 1 86  LEU 86  46  46  LEU LEU B . n 
B 1 87  GLU 87  47  47  GLU GLU B . n 
B 1 88  LYS 88  48  48  LYS LYS B . n 
B 1 89  PRO 89  49  49  PRO PRO B . n 
B 1 90  LEU 90  50  50  LEU LEU B . n 
B 1 91  PRO 91  51  51  PRO PRO B . n 
B 1 92  ARG 92  52  52  ARG ARG B . n 
B 1 93  GLU 93  53  53  GLU GLU B . n 
B 1 94  LEU 94  54  54  LEU LEU B . n 
B 1 95  HIS 95  55  55  HIS HIS B . n 
B 1 96  GLY 96  56  56  GLY GLY B . n 
B 1 97  VAL 97  57  57  VAL VAL B . n 
B 1 98  SER 98  58  58  SER SER B . n 
B 1 99  VAL 99  59  59  VAL VAL B . n 
B 1 100 VAL 100 60  60  VAL VAL B . n 
B 1 101 SER 101 61  61  SER SER B . n 
B 1 102 ASP 102 62  62  ASP ASP B . n 
B 1 103 VAL 103 63  63  VAL VAL B . n 
B 1 104 SER 104 64  64  SER SER B . n 
B 1 105 ALA 105 65  65  ALA ALA B . n 
B 1 106 LEU 106 66  66  LEU LEU B . n 
B 1 107 GLY 107 67  67  GLY GLY B . n 
B 1 108 GLN 108 68  68  GLN GLN B . n 
B 1 109 VAL 109 69  69  VAL VAL B . n 
B 1 110 ASP 110 70  70  ASP ASP B . n 
B 1 111 VAL 111 71  71  VAL VAL B . n 
B 1 112 ALA 112 72  72  ALA ALA B . n 
B 1 113 VAL 113 73  73  VAL VAL B . n 
B 1 114 LEU 114 74  74  LEU LEU B . n 
B 1 115 CYS 115 75  75  CYS CYS B . n 
B 1 116 THR 116 76  76  THR THR B . n 
B 1 117 PRO 117 77  77  PRO PRO B . n 
B 1 118 THR 118 78  78  THR THR B . n 
B 1 119 TYR 119 79  79  TYR TYR B . n 
B 1 120 GLU 120 80  80  GLU GLU B . n 
B 1 121 THR 121 81  81  THR THR B . n 
B 1 122 PRO 122 82  82  PRO PRO B . n 
B 1 123 ALA 123 83  83  ALA ALA B . n 
B 1 124 ILE 124 84  84  ILE ILE B . n 
B 1 125 ALA 125 85  85  ALA ALA B . n 
B 1 126 LYS 126 86  86  LYS LYS B . n 
B 1 127 GLU 127 87  87  GLU GLU B . n 
B 1 128 LEU 128 88  88  LEU LEU B . n 
B 1 129 LEU 129 89  89  LEU LEU B . n 
B 1 130 ALA 130 90  90  ALA ALA B . n 
B 1 131 ARG 131 91  91  ARG ARG B . n 
B 1 132 GLY 132 92  92  GLY GLY B . n 
B 1 133 ILE 133 93  93  ILE ILE B . n 
B 1 134 HIS 134 94  94  HIS HIS B . n 
B 1 135 THR 135 95  95  THR THR B . n 
B 1 136 ILE 136 96  96  ILE ILE B . n 
B 1 137 ASP 137 97  97  ASP ASP B . n 
B 1 138 SER 138 98  98  SER SER B . n 
B 1 139 PHE 139 99  99  PHE PHE B . n 
B 1 140 ASP 140 100 100 ASP ASP B . n 
B 1 141 ILE 141 101 101 ILE ILE B . n 
B 1 142 HIS 142 102 102 HIS HIS B . n 
B 1 143 GLN 143 103 103 GLN GLN B . n 
B 1 144 GLU 144 104 104 GLU GLU B . n 
B 1 145 ILE 145 105 105 ILE ILE B . n 
B 1 146 VAL 146 106 106 VAL VAL B . n 
B 1 147 GLN 147 107 107 GLN GLN B . n 
B 1 148 VAL 148 108 108 VAL VAL B . n 
B 1 149 ARG 149 109 109 ARG ARG B . n 
B 1 150 HIS 150 110 110 HIS HIS B . n 
B 1 151 GLU 151 111 111 GLU GLU B . n 
B 1 152 LEU 152 112 112 LEU LEU B . n 
B 1 153 ASP 153 113 113 ASP ASP B . n 
B 1 154 GLU 154 114 114 GLU GLU B . n 
B 1 155 VAL 155 115 115 VAL VAL B . n 
B 1 156 ALA 156 116 116 ALA ALA B . n 
B 1 157 ARG 157 117 117 ARG ARG B . n 
B 1 158 ALA 158 118 118 ALA ALA B . n 
B 1 159 HIS 159 119 119 HIS HIS B . n 
B 1 160 GLN 160 120 120 GLN GLN B . n 
B 1 161 ALA 161 121 121 ALA ALA B . n 
B 1 162 VAL 162 122 122 VAL VAL B . n 
B 1 163 ALA 163 123 123 ALA ALA B . n 
B 1 164 ILE 164 124 124 ILE ILE B . n 
B 1 165 LEU 165 125 125 LEU LEU B . n 
B 1 166 ALA 166 126 126 ALA ALA B . n 
B 1 167 ALA 167 127 127 ALA ALA B . n 
B 1 168 GLY 168 128 128 GLY GLY B . n 
B 1 169 LEU 169 129 129 LEU LEU B . n 
B 1 170 LEU 170 130 130 LEU LEU B . n 
B 1 171 PRO 171 131 131 PRO PRO B . n 
B 1 172 GLY 172 132 132 GLY GLY B . n 
B 1 173 THR 173 133 133 THR THR B . n 
B 1 174 CYS 174 134 134 CYS CYS B . n 
B 1 175 SER 175 135 135 SER SER B . n 
B 1 176 MET 176 136 136 MET MET B . n 
B 1 177 ILE 177 137 137 ILE ILE B . n 
B 1 178 ARG 178 138 138 ARG ARG B . n 
B 1 179 SER 179 139 139 SER SER B . n 
B 1 180 ILE 180 140 140 ILE ILE B . n 
B 1 181 LEU 181 141 141 LEU LEU B . n 
B 1 182 GLU 182 142 142 GLU GLU B . n 
B 1 183 PHE 183 143 143 PHE PHE B . n 
B 1 184 MET 184 144 144 MET MET B . n 
B 1 185 ALA 185 145 145 ALA ALA B . n 
B 1 186 PRO 186 146 146 PRO PRO B . n 
B 1 187 TYR 187 147 147 TYR TYR B . n 
B 1 188 GLY 188 148 148 GLY GLY B . n 
B 1 189 ILE 189 149 149 ILE ILE B . n 
B 1 190 THR 190 150 150 THR THR B . n 
B 1 191 TYR 191 151 151 TYR TYR B . n 
B 1 192 THR 192 152 152 THR THR B . n 
B 1 193 ASN 193 153 153 ASN ASN B . n 
B 1 194 VAL 194 154 154 VAL VAL B . n 
B 1 195 GLY 195 155 155 GLY GLY B . n 
B 1 196 PRO 196 156 156 PRO PRO B . n 
B 1 197 GLY 197 157 157 GLY GLY B . n 
B 1 198 MET 198 158 158 MET MET B . n 
B 1 199 SER 199 159 159 SER SER B . n 
B 1 200 MET 200 160 160 MET MET B . n 
B 1 201 SER 201 161 161 SER SER B . n 
B 1 202 ALA 202 162 162 ALA ALA B . n 
B 1 203 SER 203 163 163 SER SER B . n 
B 1 204 VAL 204 164 164 VAL VAL B . n 
B 1 205 ALA 205 165 165 ALA ALA B . n 
B 1 206 VAL 206 166 166 VAL VAL B . n 
B 1 207 LYS 207 167 167 LYS LYS B . n 
B 1 208 ALA 208 168 168 ALA ALA B . n 
B 1 209 ILE 209 169 169 ILE ILE B . n 
B 1 210 GLU 210 170 170 GLU GLU B . n 
B 1 211 GLY 211 171 171 GLY GLY B . n 
B 1 212 VAL 212 172 172 VAL VAL B . n 
B 1 213 LYS 213 173 173 LYS LYS B . n 
B 1 214 ASP 214 174 174 ASP ASP B . n 
B 1 215 ALA 215 175 175 ALA ALA B . n 
B 1 216 LEU 216 176 176 LEU LEU B . n 
B 1 217 ALA 217 177 177 ALA ALA B . n 
B 1 218 LEU 218 178 178 LEU LEU B . n 
B 1 219 ILE 219 179 179 ILE ILE B . n 
B 1 220 ILE 220 180 180 ILE ILE B . n 
B 1 221 PRO 221 181 181 PRO PRO B . n 
B 1 222 ILE 222 182 182 ILE ILE B . n 
B 1 223 GLY 223 183 183 GLY GLY B . n 
B 1 224 THR 224 184 184 THR THR B . n 
B 1 225 GLY 225 185 185 GLY GLY B . n 
B 1 226 LEU 226 186 186 LEU LEU B . n 
B 1 227 HIS 227 187 187 HIS HIS B . n 
B 1 228 ARG 228 188 188 ARG ARG B . n 
B 1 229 ARG 229 189 189 ARG ARG B . n 
B 1 230 MET 230 190 190 MET MET B . n 
B 1 231 VAL 231 191 191 VAL VAL B . n 
B 1 232 TYR 232 192 192 TYR TYR B . n 
B 1 233 VAL 233 193 193 VAL VAL B . n 
B 1 234 GLU 234 194 194 GLU GLU B . n 
B 1 235 LEU 235 195 195 LEU LEU B . n 
B 1 236 GLU 236 196 196 GLU GLU B . n 
B 1 237 GLU 237 197 197 GLU GLU B . n 
B 1 238 GLY 238 198 198 GLY GLY B . n 
B 1 239 ALA 239 199 199 ALA ALA B . n 
B 1 240 ASP 240 200 200 ASP ASP B . n 
B 1 241 PHE 241 201 201 PHE PHE B . n 
B 1 242 ALA 242 202 202 ALA ALA B . n 
B 1 243 THR 243 203 203 THR THR B . n 
B 1 244 VAL 244 204 204 VAL VAL B . n 
B 1 245 LYS 245 205 205 LYS LYS B . n 
B 1 246 GLU 246 206 206 GLU GLU B . n 
B 1 247 ARG 247 207 207 ARG ARG B . n 
B 1 248 ILE 248 208 208 ILE ILE B . n 
B 1 249 LEU 249 209 209 LEU LEU B . n 
B 1 250 GLN 250 210 210 GLN GLN B . n 
B 1 251 ASP 251 211 211 ASP ASP B . n 
B 1 252 PRO 252 212 212 PRO PRO B . n 
B 1 253 LEU 253 213 213 LEU LEU B . n 
B 1 254 PHE 254 214 214 PHE PHE B . n 
B 1 255 VAL 255 215 215 VAL VAL B . n 
B 1 256 HIS 256 216 216 HIS HIS B . n 
B 1 257 ASP 257 217 217 ASP ASP B . n 
B 1 258 GLU 258 218 218 GLU GLU B . n 
B 1 259 THR 259 219 219 THR THR B . n 
B 1 260 HIS 260 220 220 HIS HIS B . n 
B 1 261 VAL 261 221 221 VAL VAL B . n 
B 1 262 LEU 262 222 222 LEU LEU B . n 
B 1 263 GLN 263 223 223 GLN GLN B . n 
B 1 264 VAL 264 224 224 VAL VAL B . n 
B 1 265 ASP 265 225 225 ASP ASP B . n 
B 1 266 ASP 266 226 226 ASP ASP B . n 
B 1 267 VAL 267 227 227 VAL VAL B . n 
B 1 268 LYS 268 228 228 LYS LYS B . n 
B 1 269 GLN 269 229 229 GLN GLN B . n 
B 1 270 LEU 270 230 230 LEU LEU B . n 
B 1 271 ILE 271 231 231 ILE ILE B . n 
B 1 272 ASP 272 232 232 ASP ASP B . n 
B 1 273 ARG 273 233 233 ARG ARG B . n 
B 1 274 GLY 274 234 234 GLY GLY B . n 
B 1 275 ILE 275 235 235 ILE ILE B . n 
B 1 276 ALA 276 236 236 ALA ALA B . n 
B 1 277 VAL 277 237 237 VAL VAL B . n 
B 1 278 ARG 278 238 238 ARG ARG B . n 
B 1 279 MET 279 239 239 MET MET B . n 
B 1 280 GLU 280 240 240 GLU GLU B . n 
B 1 281 ARG 281 241 241 ARG ARG B . n 
B 1 282 LYS 282 242 242 LYS LYS B . n 
B 1 283 GLY 283 243 243 GLY GLY B . n 
B 1 284 VAL 284 244 244 VAL VAL B . n 
B 1 285 SER 285 245 245 SER SER B . n 
B 1 286 GLY 286 246 246 GLY GLY B . n 
B 1 287 GLN 287 247 247 GLN GLN B . n 
B 1 288 THR 288 248 248 THR THR B . n 
B 1 289 GLN 289 249 249 GLN GLN B . n 
B 1 290 ASN 290 250 250 ASN ASN B . n 
B 1 291 GLN 291 251 251 GLN GLN B . n 
B 1 292 LEU 292 252 252 LEU LEU B . n 
B 1 293 PHE 293 253 253 PHE PHE B . n 
B 1 294 THR 294 254 254 THR THR B . n 
B 1 295 TYR 295 255 255 TYR TYR B . n 
B 1 296 GLU 296 256 256 GLU GLU B . n 
B 1 297 MET 297 257 257 MET MET B . n 
B 1 298 ARG 298 258 258 ARG ARG B . n 
B 1 299 ILE 299 259 259 ILE ILE B . n 
B 1 300 ASN 300 260 260 ASN ASN B . n 
B 1 301 ASN 301 261 261 ASN ASN B . n 
B 1 302 PRO 302 262 262 PRO PRO B . n 
B 1 303 ALA 303 263 263 ALA ALA B . n 
B 1 304 LEU 304 264 264 LEU LEU B . n 
B 1 305 THR 305 265 265 THR THR B . n 
B 1 306 SER 306 266 266 SER SER B . n 
B 1 307 GLN 307 267 267 GLN GLN B . n 
B 1 308 VAL 308 268 268 VAL VAL B . n 
B 1 309 MET 309 269 269 MET MET B . n 
B 1 310 ILE 310 270 270 ILE ILE B . n 
B 1 311 ALA 311 271 271 ALA ALA B . n 
B 1 312 SER 312 272 272 SER SER B . n 
B 1 313 ALA 313 273 273 ALA ALA B . n 
B 1 314 ARG 314 274 274 ARG ARG B . n 
B 1 315 ALA 315 275 275 ALA ALA B . n 
B 1 316 ALA 316 276 276 ALA ALA B . n 
B 1 317 MET 317 277 277 MET MET B . n 
B 1 318 ARG 318 278 278 ARG ARG B . n 
B 1 319 GLN 319 279 279 GLN GLN B . n 
B 1 320 LYS 320 280 280 LYS LYS B . n 
B 1 321 PRO 321 281 281 PRO PRO B . n 
B 1 322 GLY 322 282 282 GLY GLY B . n 
B 1 323 ALA 323 283 283 ALA ALA B . n 
B 1 324 TYR 324 284 284 TYR TYR B . n 
B 1 325 THR 325 285 285 THR THR B . n 
B 1 326 MET 326 286 286 MET MET B . n 
B 1 327 ILE 327 287 287 ILE ILE B . n 
B 1 328 GLU 328 288 288 GLU GLU B . n 
B 1 329 ILE 329 289 289 ILE ILE B . n 
B 1 330 PRO 330 290 290 PRO PRO B . n 
B 1 331 ILE 331 291 291 ILE ILE B . n 
B 1 332 ILE 332 292 292 ILE ILE B . n 
B 1 333 ASP 333 293 293 ASP ASP B . n 
B 1 334 PHE 334 294 294 PHE PHE B . n 
B 1 335 LEU 335 295 295 LEU LEU B . n 
B 1 336 TYR 336 296 296 TYR TYR B . n 
B 1 337 GLY 337 297 297 GLY GLY B . n 
B 1 338 ASP 338 298 298 ASP ASP B . n 
B 1 339 ARG 339 299 299 ARG ARG B . n 
B 1 340 ASP 340 300 300 ASP ASP B . n 
B 1 341 GLU 341 301 301 GLU GLU B . n 
B 1 342 LEU 342 302 302 LEU LEU B . n 
B 1 343 ILE 343 303 303 ILE ILE B . n 
B 1 344 ARG 344 304 304 ARG ARG B . n 
B 1 345 ARG 345 305 305 ARG ARG B . n 
B 1 346 LEU 346 306 306 LEU LEU B . n 
B 1 347 VAL 347 307 307 VAL VAL B . n 
C 1 1   MET 1   -39 ?   ?   ?   C . n 
C 1 2   GLY 2   -38 ?   ?   ?   C . n 
C 1 3   SER 3   -37 ?   ?   ?   C . n 
C 1 4   SER 4   -36 ?   ?   ?   C . n 
C 1 5   HIS 5   -35 ?   ?   ?   C . n 
C 1 6   HIS 6   -34 ?   ?   ?   C . n 
C 1 7   HIS 7   -33 ?   ?   ?   C . n 
C 1 8   HIS 8   -32 ?   ?   ?   C . n 
C 1 9   HIS 9   -31 ?   ?   ?   C . n 
C 1 10  HIS 10  -30 ?   ?   ?   C . n 
C 1 11  SER 11  -29 ?   ?   ?   C . n 
C 1 12  GLY 12  -28 ?   ?   ?   C . n 
C 1 13  ILE 13  -27 ?   ?   ?   C . n 
C 1 14  VAL 14  -26 ?   ?   ?   C . n 
C 1 15  PRO 15  -25 ?   ?   ?   C . n 
C 1 16  ARG 16  -24 ?   ?   ?   C . n 
C 1 17  GLY 17  -23 ?   ?   ?   C . n 
C 1 18  SER 18  -22 ?   ?   ?   C . n 
C 1 19  HIS 19  -21 ?   ?   ?   C . n 
C 1 20  MET 20  -20 ?   ?   ?   C . n 
C 1 21  ALA 21  -19 ?   ?   ?   C . n 
C 1 22  SER 22  -18 ?   ?   ?   C . n 
C 1 23  MET 23  -17 ?   ?   ?   C . n 
C 1 24  THR 24  -16 ?   ?   ?   C . n 
C 1 25  GLY 25  -15 ?   ?   ?   C . n 
C 1 26  GLY 26  -14 ?   ?   ?   C . n 
C 1 27  GLY 27  -13 ?   ?   ?   C . n 
C 1 28  GLN 28  -12 ?   ?   ?   C . n 
C 1 29  MET 29  -11 ?   ?   ?   C . n 
C 1 30  GLY 30  -10 ?   ?   ?   C . n 
C 1 31  ARG 31  -9  ?   ?   ?   C . n 
C 1 32  GLY 32  -8  ?   ?   ?   C . n 
C 1 33  SER 33  -7  ?   ?   ?   C . n 
C 1 34  GLU 34  -6  ?   ?   ?   C . n 
C 1 35  PHE 35  -5  ?   ?   ?   C . n 
C 1 36  GLU 36  -4  ?   ?   ?   C . n 
C 1 37  LEU 37  -3  ?   ?   ?   C . n 
C 1 38  ARG 38  -2  ?   ?   ?   C . n 
C 1 39  ARG 39  -1  ?   ?   ?   C . n 
C 1 40  GLN 40  0   ?   ?   ?   C . n 
C 1 41  MET 41  1   ?   ?   ?   C . n 
C 1 42  SER 42  2   2   SER SER C . n 
C 1 43  GLU 43  3   3   GLU GLU C . n 
C 1 44  ILE 44  4   4   ILE ILE C . n 
C 1 45  ARG 45  5   5   ARG ARG C . n 
C 1 46  THR 46  6   6   THR THR C . n 
C 1 47  GLU 47  7   7   GLU GLU C . n 
C 1 48  ARG 48  8   8   ARG ARG C . n 
C 1 49  PRO 49  9   9   PRO PRO C . n 
C 1 50  ILE 50  10  10  ILE ILE C . n 
C 1 51  ARG 51  11  11  ARG ARG C . n 
C 1 52  VAL 52  12  12  VAL VAL C . n 
C 1 53  ALA 53  13  13  ALA ALA C . n 
C 1 54  ILE 54  14  14  ILE ILE C . n 
C 1 55  ILE 55  15  15  ILE ILE C . n 
C 1 56  GLY 56  16  16  GLY GLY C . n 
C 1 57  TYR 57  17  17  TYR TYR C . n 
C 1 58  GLY 58  18  18  GLY GLY C . n 
C 1 59  ASN 59  19  19  ASN ASN C . n 
C 1 60  ILE 60  20  20  ILE ILE C . n 
C 1 61  GLY 61  21  21  GLY GLY C . n 
C 1 62  GLN 62  22  22  GLN GLN C . n 
C 1 63  TYR 63  23  23  TYR TYR C . n 
C 1 64  ALA 64  24  24  ALA ALA C . n 
C 1 65  LEU 65  25  25  LEU LEU C . n 
C 1 66  GLN 66  26  26  GLN GLN C . n 
C 1 67  ALA 67  27  27  ALA ALA C . n 
C 1 68  VAL 68  28  28  VAL VAL C . n 
C 1 69  GLU 69  29  29  GLU GLU C . n 
C 1 70  GLU 70  30  30  GLU GLU C . n 
C 1 71  ALA 71  31  31  ALA ALA C . n 
C 1 72  PRO 72  32  32  PRO PRO C . n 
C 1 73  ASP 73  33  33  ASP ASP C . n 
C 1 74  MET 74  34  34  MET MET C . n 
C 1 75  GLU 75  35  35  GLU GLU C . n 
C 1 76  LEU 76  36  36  LEU LEU C . n 
C 1 77  ALA 77  37  37  ALA ALA C . n 
C 1 78  GLY 78  38  38  GLY GLY C . n 
C 1 79  VAL 79  39  39  VAL VAL C . n 
C 1 80  VAL 80  40  40  VAL VAL C . n 
C 1 81  ARG 81  41  41  ARG ARG C . n 
C 1 82  ARG 82  42  42  ARG ARG C . n 
C 1 83  GLN 83  43  43  GLN GLN C . n 
C 1 84  SER 84  44  44  SER SER C . n 
C 1 85  SER 85  45  45  SER SER C . n 
C 1 86  LEU 86  46  46  LEU LEU C . n 
C 1 87  GLU 87  47  47  GLU GLU C . n 
C 1 88  LYS 88  48  48  LYS LYS C . n 
C 1 89  PRO 89  49  49  PRO PRO C . n 
C 1 90  LEU 90  50  50  LEU LEU C . n 
C 1 91  PRO 91  51  51  PRO PRO C . n 
C 1 92  ARG 92  52  52  ARG ARG C . n 
C 1 93  GLU 93  53  53  GLU GLU C . n 
C 1 94  LEU 94  54  54  LEU LEU C . n 
C 1 95  HIS 95  55  55  HIS HIS C . n 
C 1 96  GLY 96  56  56  GLY GLY C . n 
C 1 97  VAL 97  57  57  VAL VAL C . n 
C 1 98  SER 98  58  58  SER SER C . n 
C 1 99  VAL 99  59  59  VAL VAL C . n 
C 1 100 VAL 100 60  60  VAL VAL C . n 
C 1 101 SER 101 61  61  SER SER C . n 
C 1 102 ASP 102 62  62  ASP ASP C . n 
C 1 103 VAL 103 63  63  VAL VAL C . n 
C 1 104 SER 104 64  64  SER SER C . n 
C 1 105 ALA 105 65  65  ALA ALA C . n 
C 1 106 LEU 106 66  66  LEU LEU C . n 
C 1 107 GLY 107 67  67  GLY GLY C . n 
C 1 108 GLN 108 68  68  GLN GLN C . n 
C 1 109 VAL 109 69  69  VAL VAL C . n 
C 1 110 ASP 110 70  70  ASP ASP C . n 
C 1 111 VAL 111 71  71  VAL VAL C . n 
C 1 112 ALA 112 72  72  ALA ALA C . n 
C 1 113 VAL 113 73  73  VAL VAL C . n 
C 1 114 LEU 114 74  74  LEU LEU C . n 
C 1 115 CYS 115 75  75  CYS CYS C . n 
C 1 116 THR 116 76  76  THR THR C . n 
C 1 117 PRO 117 77  77  PRO PRO C . n 
C 1 118 THR 118 78  78  THR THR C . n 
C 1 119 TYR 119 79  79  TYR TYR C . n 
C 1 120 GLU 120 80  80  GLU GLU C . n 
C 1 121 THR 121 81  81  THR THR C . n 
C 1 122 PRO 122 82  82  PRO PRO C . n 
C 1 123 ALA 123 83  83  ALA ALA C . n 
C 1 124 ILE 124 84  84  ILE ILE C . n 
C 1 125 ALA 125 85  85  ALA ALA C . n 
C 1 126 LYS 126 86  86  LYS LYS C . n 
C 1 127 GLU 127 87  87  GLU GLU C . n 
C 1 128 LEU 128 88  88  LEU LEU C . n 
C 1 129 LEU 129 89  89  LEU LEU C . n 
C 1 130 ALA 130 90  90  ALA ALA C . n 
C 1 131 ARG 131 91  91  ARG ARG C . n 
C 1 132 GLY 132 92  92  GLY GLY C . n 
C 1 133 ILE 133 93  93  ILE ILE C . n 
C 1 134 HIS 134 94  94  HIS HIS C . n 
C 1 135 THR 135 95  95  THR THR C . n 
C 1 136 ILE 136 96  96  ILE ILE C . n 
C 1 137 ASP 137 97  97  ASP ASP C . n 
C 1 138 SER 138 98  98  SER SER C . n 
C 1 139 PHE 139 99  99  PHE PHE C . n 
C 1 140 ASP 140 100 100 ASP ASP C . n 
C 1 141 ILE 141 101 101 ILE ILE C . n 
C 1 142 HIS 142 102 102 HIS HIS C . n 
C 1 143 GLN 143 103 103 GLN GLN C . n 
C 1 144 GLU 144 104 104 GLU GLU C . n 
C 1 145 ILE 145 105 105 ILE ILE C . n 
C 1 146 VAL 146 106 106 VAL VAL C . n 
C 1 147 GLN 147 107 107 GLN GLN C . n 
C 1 148 VAL 148 108 108 VAL VAL C . n 
C 1 149 ARG 149 109 109 ARG ARG C . n 
C 1 150 HIS 150 110 110 HIS HIS C . n 
C 1 151 GLU 151 111 111 GLU GLU C . n 
C 1 152 LEU 152 112 112 LEU LEU C . n 
C 1 153 ASP 153 113 113 ASP ASP C . n 
C 1 154 GLU 154 114 114 GLU GLU C . n 
C 1 155 VAL 155 115 115 VAL VAL C . n 
C 1 156 ALA 156 116 116 ALA ALA C . n 
C 1 157 ARG 157 117 117 ARG ARG C . n 
C 1 158 ALA 158 118 118 ALA ALA C . n 
C 1 159 HIS 159 119 119 HIS HIS C . n 
C 1 160 GLN 160 120 120 GLN GLN C . n 
C 1 161 ALA 161 121 121 ALA ALA C . n 
C 1 162 VAL 162 122 122 VAL VAL C . n 
C 1 163 ALA 163 123 123 ALA ALA C . n 
C 1 164 ILE 164 124 124 ILE ILE C . n 
C 1 165 LEU 165 125 125 LEU LEU C . n 
C 1 166 ALA 166 126 126 ALA ALA C . n 
C 1 167 ALA 167 127 127 ALA ALA C . n 
C 1 168 GLY 168 128 128 GLY GLY C . n 
C 1 169 LEU 169 129 129 LEU LEU C . n 
C 1 170 LEU 170 130 130 LEU LEU C . n 
C 1 171 PRO 171 131 131 PRO PRO C . n 
C 1 172 GLY 172 132 132 GLY GLY C . n 
C 1 173 THR 173 133 133 THR THR C . n 
C 1 174 CYS 174 134 134 CYS CYS C . n 
C 1 175 SER 175 135 135 SER SER C . n 
C 1 176 MET 176 136 136 MET MET C . n 
C 1 177 ILE 177 137 137 ILE ILE C . n 
C 1 178 ARG 178 138 138 ARG ARG C . n 
C 1 179 SER 179 139 139 SER SER C . n 
C 1 180 ILE 180 140 140 ILE ILE C . n 
C 1 181 LEU 181 141 141 LEU LEU C . n 
C 1 182 GLU 182 142 142 GLU GLU C . n 
C 1 183 PHE 183 143 143 PHE PHE C . n 
C 1 184 MET 184 144 144 MET MET C . n 
C 1 185 ALA 185 145 145 ALA ALA C . n 
C 1 186 PRO 186 146 146 PRO PRO C . n 
C 1 187 TYR 187 147 147 TYR TYR C . n 
C 1 188 GLY 188 148 148 GLY GLY C . n 
C 1 189 ILE 189 149 149 ILE ILE C . n 
C 1 190 THR 190 150 150 THR THR C . n 
C 1 191 TYR 191 151 151 TYR TYR C . n 
C 1 192 THR 192 152 152 THR THR C . n 
C 1 193 ASN 193 153 153 ASN ASN C . n 
C 1 194 VAL 194 154 154 VAL VAL C . n 
C 1 195 GLY 195 155 155 GLY GLY C . n 
C 1 196 PRO 196 156 156 PRO PRO C . n 
C 1 197 GLY 197 157 157 GLY GLY C . n 
C 1 198 MET 198 158 158 MET MET C . n 
C 1 199 SER 199 159 159 SER SER C . n 
C 1 200 MET 200 160 160 MET MET C . n 
C 1 201 SER 201 161 161 SER SER C . n 
C 1 202 ALA 202 162 162 ALA ALA C . n 
C 1 203 SER 203 163 163 SER SER C . n 
C 1 204 VAL 204 164 164 VAL VAL C . n 
C 1 205 ALA 205 165 165 ALA ALA C . n 
C 1 206 VAL 206 166 166 VAL VAL C . n 
C 1 207 LYS 207 167 167 LYS LYS C . n 
C 1 208 ALA 208 168 168 ALA ALA C . n 
C 1 209 ILE 209 169 169 ILE ILE C . n 
C 1 210 GLU 210 170 170 GLU GLU C . n 
C 1 211 GLY 211 171 171 GLY GLY C . n 
C 1 212 VAL 212 172 172 VAL VAL C . n 
C 1 213 LYS 213 173 173 LYS LYS C . n 
C 1 214 ASP 214 174 174 ASP ASP C . n 
C 1 215 ALA 215 175 175 ALA ALA C . n 
C 1 216 LEU 216 176 176 LEU LEU C . n 
C 1 217 ALA 217 177 177 ALA ALA C . n 
C 1 218 LEU 218 178 178 LEU LEU C . n 
C 1 219 ILE 219 179 179 ILE ILE C . n 
C 1 220 ILE 220 180 180 ILE ILE C . n 
C 1 221 PRO 221 181 181 PRO PRO C . n 
C 1 222 ILE 222 182 182 ILE ILE C . n 
C 1 223 GLY 223 183 183 GLY GLY C . n 
C 1 224 THR 224 184 184 THR THR C . n 
C 1 225 GLY 225 185 185 GLY GLY C . n 
C 1 226 LEU 226 186 186 LEU LEU C . n 
C 1 227 HIS 227 187 187 HIS HIS C . n 
C 1 228 ARG 228 188 188 ARG ARG C . n 
C 1 229 ARG 229 189 189 ARG ARG C . n 
C 1 230 MET 230 190 190 MET MET C . n 
C 1 231 VAL 231 191 191 VAL VAL C . n 
C 1 232 TYR 232 192 192 TYR TYR C . n 
C 1 233 VAL 233 193 193 VAL VAL C . n 
C 1 234 GLU 234 194 194 GLU GLU C . n 
C 1 235 LEU 235 195 195 LEU LEU C . n 
C 1 236 GLU 236 196 ?   ?   ?   C . n 
C 1 237 GLU 237 197 197 GLU GLU C . n 
C 1 238 GLY 238 198 198 GLY GLY C . n 
C 1 239 ALA 239 199 199 ALA ALA C . n 
C 1 240 ASP 240 200 200 ASP ASP C . n 
C 1 241 PHE 241 201 201 PHE PHE C . n 
C 1 242 ALA 242 202 202 ALA ALA C . n 
C 1 243 THR 243 203 203 THR THR C . n 
C 1 244 VAL 244 204 204 VAL VAL C . n 
C 1 245 LYS 245 205 205 LYS LYS C . n 
C 1 246 GLU 246 206 206 GLU GLU C . n 
C 1 247 ARG 247 207 207 ARG ARG C . n 
C 1 248 ILE 248 208 208 ILE ILE C . n 
C 1 249 LEU 249 209 209 LEU LEU C . n 
C 1 250 GLN 250 210 210 GLN GLN C . n 
C 1 251 ASP 251 211 211 ASP ASP C . n 
C 1 252 PRO 252 212 212 PRO PRO C . n 
C 1 253 LEU 253 213 213 LEU LEU C . n 
C 1 254 PHE 254 214 214 PHE PHE C . n 
C 1 255 VAL 255 215 215 VAL VAL C . n 
C 1 256 HIS 256 216 216 HIS HIS C . n 
C 1 257 ASP 257 217 217 ASP ASP C . n 
C 1 258 GLU 258 218 218 GLU GLU C . n 
C 1 259 THR 259 219 219 THR THR C . n 
C 1 260 HIS 260 220 220 HIS HIS C . n 
C 1 261 VAL 261 221 221 VAL VAL C . n 
C 1 262 LEU 262 222 222 LEU LEU C . n 
C 1 263 GLN 263 223 223 GLN GLN C . n 
C 1 264 VAL 264 224 224 VAL VAL C . n 
C 1 265 ASP 265 225 225 ASP ASP C . n 
C 1 266 ASP 266 226 226 ASP ASP C . n 
C 1 267 VAL 267 227 227 VAL VAL C . n 
C 1 268 LYS 268 228 228 LYS LYS C . n 
C 1 269 GLN 269 229 229 GLN GLN C . n 
C 1 270 LEU 270 230 230 LEU LEU C . n 
C 1 271 ILE 271 231 231 ILE ILE C . n 
C 1 272 ASP 272 232 232 ASP ASP C . n 
C 1 273 ARG 273 233 233 ARG ARG C . n 
C 1 274 GLY 274 234 234 GLY GLY C . n 
C 1 275 ILE 275 235 235 ILE ILE C . n 
C 1 276 ALA 276 236 236 ALA ALA C . n 
C 1 277 VAL 277 237 237 VAL VAL C . n 
C 1 278 ARG 278 238 238 ARG ARG C . n 
C 1 279 MET 279 239 239 MET MET C . n 
C 1 280 GLU 280 240 240 GLU GLU C . n 
C 1 281 ARG 281 241 241 ARG ARG C . n 
C 1 282 LYS 282 242 242 LYS LYS C . n 
C 1 283 GLY 283 243 243 GLY GLY C . n 
C 1 284 VAL 284 244 244 VAL VAL C . n 
C 1 285 SER 285 245 245 SER SER C . n 
C 1 286 GLY 286 246 246 GLY GLY C . n 
C 1 287 GLN 287 247 247 GLN GLN C . n 
C 1 288 THR 288 248 248 THR THR C . n 
C 1 289 GLN 289 249 249 GLN GLN C . n 
C 1 290 ASN 290 250 250 ASN ASN C . n 
C 1 291 GLN 291 251 251 GLN GLN C . n 
C 1 292 LEU 292 252 252 LEU LEU C . n 
C 1 293 PHE 293 253 253 PHE PHE C . n 
C 1 294 THR 294 254 254 THR THR C . n 
C 1 295 TYR 295 255 255 TYR TYR C . n 
C 1 296 GLU 296 256 256 GLU GLU C . n 
C 1 297 MET 297 257 257 MET MET C . n 
C 1 298 ARG 298 258 258 ARG ARG C . n 
C 1 299 ILE 299 259 259 ILE ILE C . n 
C 1 300 ASN 300 260 260 ASN ASN C . n 
C 1 301 ASN 301 261 261 ASN ASN C . n 
C 1 302 PRO 302 262 262 PRO PRO C . n 
C 1 303 ALA 303 263 263 ALA ALA C . n 
C 1 304 LEU 304 264 264 LEU LEU C . n 
C 1 305 THR 305 265 265 THR THR C . n 
C 1 306 SER 306 266 266 SER SER C . n 
C 1 307 GLN 307 267 267 GLN GLN C . n 
C 1 308 VAL 308 268 268 VAL VAL C . n 
C 1 309 MET 309 269 269 MET MET C . n 
C 1 310 ILE 310 270 270 ILE ILE C . n 
C 1 311 ALA 311 271 271 ALA ALA C . n 
C 1 312 SER 312 272 272 SER SER C . n 
C 1 313 ALA 313 273 273 ALA ALA C . n 
C 1 314 ARG 314 274 274 ARG ARG C . n 
C 1 315 ALA 315 275 275 ALA ALA C . n 
C 1 316 ALA 316 276 276 ALA ALA C . n 
C 1 317 MET 317 277 277 MET MET C . n 
C 1 318 ARG 318 278 278 ARG ARG C . n 
C 1 319 GLN 319 279 279 GLN GLN C . n 
C 1 320 LYS 320 280 280 LYS LYS C . n 
C 1 321 PRO 321 281 281 PRO PRO C . n 
C 1 322 GLY 322 282 282 GLY GLY C . n 
C 1 323 ALA 323 283 283 ALA ALA C . n 
C 1 324 TYR 324 284 284 TYR TYR C . n 
C 1 325 THR 325 285 285 THR THR C . n 
C 1 326 MET 326 286 286 MET MET C . n 
C 1 327 ILE 327 287 287 ILE ILE C . n 
C 1 328 GLU 328 288 288 GLU GLU C . n 
C 1 329 ILE 329 289 289 ILE ILE C . n 
C 1 330 PRO 330 290 290 PRO PRO C . n 
C 1 331 ILE 331 291 291 ILE ILE C . n 
C 1 332 ILE 332 292 292 ILE ILE C . n 
C 1 333 ASP 333 293 293 ASP ASP C . n 
C 1 334 PHE 334 294 294 PHE PHE C . n 
C 1 335 LEU 335 295 295 LEU LEU C . n 
C 1 336 TYR 336 296 296 TYR TYR C . n 
C 1 337 GLY 337 297 297 GLY GLY C . n 
C 1 338 ASP 338 298 298 ASP ASP C . n 
C 1 339 ARG 339 299 299 ARG ARG C . n 
C 1 340 ASP 340 300 300 ASP ASP C . n 
C 1 341 GLU 341 301 301 GLU GLU C . n 
C 1 342 LEU 342 302 302 LEU LEU C . n 
C 1 343 ILE 343 303 303 ILE ILE C . n 
C 1 344 ARG 344 304 304 ARG ARG C . n 
C 1 345 ARG 345 305 305 ARG ARG C . n 
C 1 346 LEU 346 306 306 LEU LEU C . n 
C 1 347 VAL 347 307 307 VAL VAL C . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        NAP 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   NAP 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
D 2 NAP 1  401 401 NAP NAP A . 
E 3 OXM 1  402 402 OXM OXM A . 
F 4 IMD 1  403 403 IMD IMD A . 
G 5 ACY 1  404 404 ACY ACT A . 
H 2 NAP 1  401 401 NAP NAP B . 
I 3 OXM 1  402 402 OXM OXM B . 
J 4 IMD 1  403 403 IMD IMD B . 
K 4 IMD 1  404 404 IMD IMD B . 
L 4 IMD 1  405 405 IMD IMD B . 
M 5 ACY 1  406 406 ACY ACT B . 
N 4 IMD 1  407 407 IMD IMD B . 
O 2 NAP 1  401 401 NAP NAP C . 
P 3 OXM 1  402 402 OXM OXM C . 
Q 3 OXM 1  403 403 OXM OXM C . 
R 4 IMD 1  404 404 IMD IMD C . 
S 6 HOH 1  501 1   HOH HOH A . 
S 6 HOH 2  502 19  HOH HOH A . 
S 6 HOH 3  503 26  HOH HOH A . 
S 6 HOH 4  504 31  HOH HOH A . 
S 6 HOH 5  505 9   HOH HOH A . 
S 6 HOH 6  506 4   HOH HOH A . 
S 6 HOH 7  507 2   HOH HOH A . 
S 6 HOH 8  508 40  HOH HOH A . 
S 6 HOH 9  509 6   HOH HOH A . 
S 6 HOH 10 510 13  HOH HOH A . 
S 6 HOH 11 511 17  HOH HOH A . 
S 6 HOH 12 512 30  HOH HOH A . 
S 6 HOH 13 513 24  HOH HOH A . 
S 6 HOH 14 514 42  HOH HOH A . 
S 6 HOH 15 515 43  HOH HOH A . 
S 6 HOH 16 516 16  HOH HOH A . 
S 6 HOH 17 517 12  HOH HOH A . 
S 6 HOH 18 518 25  HOH HOH A . 
T 6 HOH 1  501 22  HOH HOH B . 
T 6 HOH 2  502 5   HOH HOH B . 
T 6 HOH 3  503 39  HOH HOH B . 
T 6 HOH 4  504 32  HOH HOH B . 
T 6 HOH 5  505 34  HOH HOH B . 
T 6 HOH 6  506 23  HOH HOH B . 
T 6 HOH 7  507 10  HOH HOH B . 
T 6 HOH 8  508 37  HOH HOH B . 
T 6 HOH 9  509 36  HOH HOH B . 
T 6 HOH 10 510 38  HOH HOH B . 
T 6 HOH 11 511 11  HOH HOH B . 
T 6 HOH 12 512 18  HOH HOH B . 
T 6 HOH 13 513 27  HOH HOH B . 
T 6 HOH 14 514 20  HOH HOH B . 
T 6 HOH 15 515 41  HOH HOH B . 
U 6 HOH 1  501 33  HOH HOH C . 
U 6 HOH 2  502 29  HOH HOH C . 
U 6 HOH 3  503 7   HOH HOH C . 
U 6 HOH 4  504 8   HOH HOH C . 
U 6 HOH 5  505 28  HOH HOH C . 
U 6 HOH 6  506 3   HOH HOH C . 
U 6 HOH 7  507 15  HOH HOH C . 
U 6 HOH 8  508 35  HOH HOH C . 
U 6 HOH 9  509 45  HOH HOH C . 
U 6 HOH 10 510 14  HOH HOH C . 
U 6 HOH 11 511 44  HOH HOH C . 
U 6 HOH 12 512 21  HOH HOH C . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? 1.20.1_4487 1 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? 1.20.1_4487 2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? autoPROC ? ? ? .           3 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless  ? ? ? .           4 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER   ? ? ? .           5 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9KSN 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     156.070 
_cell.length_a_esd                 ? 
_cell.length_b                     156.070 
_cell.length_b_esd                 ? 
_cell.length_c                     112.310 
_cell.length_c_esd                 ? 
_cell.volume                       2735629.561 
_cell.volume_esd                   ? 
_cell.Z_PDB                        24 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9KSN 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                96 
_symmetry.space_group_name_Hall            'P 4nw 2abw' 
_symmetry.space_group_name_H-M             'P 43 21 2' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9KSN 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.98 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          58.79 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              6.75 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    
;20 mM sodium formate; 20 mM ammonium acetate; 20 mM sodium citrate tribasic dihydrate; 20 mM potassium sodium tartrate tetrahydrate; 20 mM sodium oxamate; 100 mM MES/imidazole, pH 6.75; 20% (v/v) ethylene glycol and 10% (w/v) PEG 8000
;
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            291 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER2 S 9M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2024-03-24 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.987 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRL BEAMLINE BL12-1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.987 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL12-1 
_diffrn_source.pdbx_synchrotron_site       SSRL 
# 
_reflns.B_iso_Wilson_estimate                          55.66 
_reflns.entry_id                                       9KSN 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.65 
_reflns.d_resolution_low                               50.05 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     40873 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           100 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                26.6 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          17.0 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.999 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.65 
_reflns_shell.d_res_low                                     2.76 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             4548 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.848 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               66.67 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9KSN 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.65 
_refine.ls_d_res_low                             50.05 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     40792 
_refine.ls_number_reflns_R_free                  1976 
_refine.ls_number_reflns_R_work                  38816 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.93 
_refine.ls_percent_reflns_R_free                 4.84 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2028 
_refine.ls_R_factor_R_free                       0.2375 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2011 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.35 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      8ZMX 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 27.3839 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.3443 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.65 
_refine_hist.d_res_low                        50.05 
_refine_hist.number_atoms_solvent             45 
_refine_hist.number_atoms_total               7302 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        7051 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         206 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0027  ? 7382  ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.7182  ? 10024 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0502  ? 1175  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0042  ? 1293  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 18.8985 ? 2796  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_restr_ncs.pdbx_ordinal 
_refine_ls_restr_ncs.pdbx_refine_id 
_refine_ls_restr_ncs.dom_id 
_refine_ls_restr_ncs.pdbx_ens_id 
_refine_ls_restr_ncs.rms_dev_position 
_refine_ls_restr_ncs.weight_position 
_refine_ls_restr_ncs.rms_dev_B_iso 
_refine_ls_restr_ncs.weight_B_iso 
_refine_ls_restr_ncs.pdbx_type 
_refine_ls_restr_ncs.pdbx_asym_id 
_refine_ls_restr_ncs.pdbx_auth_asym_id 
_refine_ls_restr_ncs.pdbx_number 
_refine_ls_restr_ncs.pdbx_rms 
_refine_ls_restr_ncs.pdbx_weight 
_refine_ls_restr_ncs.ncs_model_details 
1 'X-RAY DIFFRACTION' d_2 ens_1 1.24249591717 ? ? ? 'Torsion NCS' A A ? ? ? ? 
2 'X-RAY DIFFRACTION' d_3 ens_1 1.72169322996 ? ? ? 'Torsion NCS' A A ? ? ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.65 2.72  . . 170 2707 99.93  . . . . 0.2963 . . . . . . . . . . . 0.3588 
'X-RAY DIFFRACTION' 2.72 2.79  . . 125 2750 99.93  . . . . 0.2726 . . . . . . . . . . . 0.2897 
'X-RAY DIFFRACTION' 2.79 2.87  . . 140 2716 99.96  . . . . 0.2505 . . . . . . . . . . . 0.3044 
'X-RAY DIFFRACTION' 2.87 2.96  . . 154 2710 99.97  . . . . 0.2576 . . . . . . . . . . . 0.3180 
'X-RAY DIFFRACTION' 2.96 3.07  . . 124 2743 99.93  . . . . 0.2469 . . . . . . . . . . . 0.3029 
'X-RAY DIFFRACTION' 3.07 3.19  . . 134 2752 100.00 . . . . 0.2590 . . . . . . . . . . . 0.3056 
'X-RAY DIFFRACTION' 3.19 3.34  . . 130 2750 100.00 . . . . 0.2364 . . . . . . . . . . . 0.3185 
'X-RAY DIFFRACTION' 3.34 3.51  . . 156 2744 100.00 . . . . 0.2082 . . . . . . . . . . . 0.2228 
'X-RAY DIFFRACTION' 3.51 3.73  . . 132 2774 99.97  . . . . 0.1995 . . . . . . . . . . . 0.2525 
'X-RAY DIFFRACTION' 3.73 4.02  . . 148 2762 99.97  . . . . 0.2004 . . . . . . . . . . . 0.2401 
'X-RAY DIFFRACTION' 4.02 4.43  . . 134 2781 100.00 . . . . 0.1757 . . . . . . . . . . . 0.1864 
'X-RAY DIFFRACTION' 4.43 5.07  . . 148 2810 100.00 . . . . 0.1617 . . . . . . . . . . . 0.1783 
'X-RAY DIFFRACTION' 5.07 6.38  . . 140 2836 100.00 . . . . 0.1979 . . . . . . . . . . . 0.2095 
'X-RAY DIFFRACTION' 6.39 50.05 . . 141 2981 99.40  . . . . 0.1684 . . . . . . . . . . . 0.2178 
# 
loop_
_struct_ncs_oper.id 
_struct_ncs_oper.code 
_struct_ncs_oper.matrix[1][1] 
_struct_ncs_oper.matrix[1][2] 
_struct_ncs_oper.matrix[1][3] 
_struct_ncs_oper.matrix[2][1] 
_struct_ncs_oper.matrix[2][2] 
_struct_ncs_oper.matrix[2][3] 
_struct_ncs_oper.matrix[3][1] 
_struct_ncs_oper.matrix[3][2] 
_struct_ncs_oper.matrix[3][3] 
_struct_ncs_oper.vector[1] 
_struct_ncs_oper.vector[2] 
_struct_ncs_oper.vector[3] 
_struct_ncs_oper.details 
1 given -0.99945029039  0.0244032899938  0.0224409553558 0.0225582189782  0.00454057921008 0.999735219894   0.0242949335527 
0.999691883821   -0.00508857796952 29.704409553   -53.1579518732 52.771517536  ? 
2 given 0.0205271783373 0.00492790039801 0.999777150543  -0.0103850878443 -0.999932853195  0.00514189192329 0.999735357432  
-0.0104883220657 -0.0204746233244  -23.9025249209 -48.879460525  24.3576956426 ? 
# 
loop_
_struct_ncs_dom.pdbx_ens_id 
_struct_ncs_dom.id 
_struct_ncs_dom.details 
ens_1 d_1 
;(chain "A" and (resid 5 through 196 or resid 198 through 232 or resid 234 through 307 or resid 401 through 402))
;
ens_1 d_2 
;(chain "B" and (resid 5 through 196 or resid 198 through 232 or resid 234 through 307 or resid 401 through 402))
;
ens_1 d_3 
;(chain "C" and (resid 5 through 232 or resid 234 through 307 or resid 401 through 402))
;
# 
loop_
_struct_ncs_dom_lim.pdbx_ens_id 
_struct_ncs_dom_lim.dom_id 
_struct_ncs_dom_lim.pdbx_component_id 
_struct_ncs_dom_lim.beg_label_asym_id 
_struct_ncs_dom_lim.beg_label_comp_id 
_struct_ncs_dom_lim.beg_label_seq_id 
_struct_ncs_dom_lim.beg_label_alt_id 
_struct_ncs_dom_lim.end_label_asym_id 
_struct_ncs_dom_lim.end_label_comp_id 
_struct_ncs_dom_lim.end_label_seq_id 
_struct_ncs_dom_lim.end_label_alt_id 
_struct_ncs_dom_lim.beg_auth_asym_id 
_struct_ncs_dom_lim.beg_auth_comp_id 
_struct_ncs_dom_lim.beg_auth_seq_id 
_struct_ncs_dom_lim.end_auth_asym_id 
_struct_ncs_dom_lim.end_auth_comp_id 
_struct_ncs_dom_lim.end_auth_seq_id 
_struct_ncs_dom_lim.pdbx_refine_code 
_struct_ncs_dom_lim.selection_details 
ens_1 d_1 1 A ARG 45  . A GLU 236 . A ARG 5   A GLU 196 ? ? 
ens_1 d_1 2 A GLY 238 . A ASP 272 . A GLY 198 A ASP 232 ? ? 
ens_1 d_1 3 A GLY 274 . A VAL 347 . A GLY 234 A VAL 307 ? ? 
ens_1 d_1 4 D NAP .   . D NAP .   . A NAP 401 A NAP 401 ? ? 
ens_1 d_1 5 E OXM .   . E OXM .   . A OXM 402 A OXM 402 ? ? 
ens_1 d_2 1 B ARG 45  . B GLU 236 . B ARG 5   B GLU 196 ? ? 
ens_1 d_2 2 B GLY 238 . B ASP 272 . B GLY 198 B ASP 232 ? ? 
ens_1 d_2 3 B GLY 274 . B VAL 347 . B GLY 234 B VAL 307 ? ? 
ens_1 d_2 4 H NAP .   . H NAP .   . B NAP 401 B NAP 401 ? ? 
ens_1 d_2 5 I OXM .   . I OXM .   . B OXM 402 B OXM 402 ? ? 
ens_1 d_3 1 C ARG 45  . C ASP 272 . C ARG 5   C ASP 232 ? ? 
ens_1 d_3 2 C GLY 274 . C VAL 347 . C GLY 234 C VAL 307 ? ? 
ens_1 d_3 3 O NAP .   . O NAP .   . C NAP 401 C NAP 401 ? ? 
ens_1 d_3 4 P OXM .   . P OXM .   . C OXM 402 C OXM 402 ? ? 
# 
_struct_ncs_ens.id        ens_1 
_struct_ncs_ens.details   ? 
# 
loop_
_struct_ncs_ens_gen.ens_id 
_struct_ncs_ens_gen.dom_id_1 
_struct_ncs_ens_gen.dom_id_2 
_struct_ncs_ens_gen.oper_id 
ens_1 d_2 d_1 1 
ens_1 d_3 d_1 2 
# 
_struct.entry_id                     9KSN 
_struct.title                        
'Crystal structure of meso-diaminopimelate dehydrogenase from Bacillus thermozeamaize mutant M9 complexed with NADP+' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9KSN 
_struct_keywords.text            'Amino acid dehydrogenase, Complex, NADP+, OXIDOREDUCTASE' 
_struct_keywords.pdbx_keywords   OXIDOREDUCTASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 2 ? 
E N N 3 ? 
F N N 4 ? 
G N N 5 ? 
H N N 2 ? 
I N N 3 ? 
J N N 4 ? 
K N N 4 ? 
L N N 4 ? 
M N N 5 ? 
N N N 4 ? 
O N N 2 ? 
P N N 3 ? 
Q N N 3 ? 
R N N 4 ? 
S N N 6 ? 
T N N 6 ? 
U N N 6 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A0A1Y3PXT7_9BACI 
_struct_ref.pdbx_db_accession          A0A1Y3PXT7 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MSEIRTERPIRVAIIGYGNIGQYALQAVEEAPDMELAGVVRRQSSLEKPLPRELHGVSVVSDVSALGQVDVAVLCTPTRE
TPAIAKELLARGIHTIDSFDIHQEIVQVRHELDEVARAHQAVAILAAGWDPGTDSMIRSILEFMAPYGITYTNFGPGMSM
GHSVAVKAIEGVKDALSLTIPIGTGLHRRMVYVELEEGADFATVKERILQDPYFVHDETHVLQVDDVKQLIDRGHGVRME
RKGVSGQTQNQLFTYEMRINNPALTSQVMIASARAAMRQKPGAYTMIEIPIIDFLYGDRDELIRRLV
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9KSN A 41 ? 347 ? A0A1Y3PXT7 1 ? 307 ? 1 307 
2 1 9KSN B 41 ? 347 ? A0A1Y3PXT7 1 ? 307 ? 1 307 
3 1 9KSN C 41 ? 347 ? A0A1Y3PXT7 1 ? 307 ? 1 307 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9KSN MET A 1   ? UNP A0A1Y3PXT7 ?   ?   'initiating methionine' -39 1   
1 9KSN GLY A 2   ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -38 2   
1 9KSN SER A 3   ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -37 3   
1 9KSN SER A 4   ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -36 4   
1 9KSN HIS A 5   ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -35 5   
1 9KSN HIS A 6   ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -34 6   
1 9KSN HIS A 7   ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -33 7   
1 9KSN HIS A 8   ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -32 8   
1 9KSN HIS A 9   ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -31 9   
1 9KSN HIS A 10  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -30 10  
1 9KSN SER A 11  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -29 11  
1 9KSN GLY A 12  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -28 12  
1 9KSN ILE A 13  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -27 13  
1 9KSN VAL A 14  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -26 14  
1 9KSN PRO A 15  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -25 15  
1 9KSN ARG A 16  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -24 16  
1 9KSN GLY A 17  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -23 17  
1 9KSN SER A 18  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -22 18  
1 9KSN HIS A 19  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -21 19  
1 9KSN MET A 20  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -20 20  
1 9KSN ALA A 21  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -19 21  
1 9KSN SER A 22  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -18 22  
1 9KSN MET A 23  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -17 23  
1 9KSN THR A 24  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -16 24  
1 9KSN GLY A 25  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -15 25  
1 9KSN GLY A 26  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -14 26  
1 9KSN GLY A 27  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -13 27  
1 9KSN GLN A 28  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -12 28  
1 9KSN MET A 29  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -11 29  
1 9KSN GLY A 30  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -10 30  
1 9KSN ARG A 31  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -9  31  
1 9KSN GLY A 32  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -8  32  
1 9KSN SER A 33  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -7  33  
1 9KSN GLU A 34  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -6  34  
1 9KSN PHE A 35  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -5  35  
1 9KSN GLU A 36  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -4  36  
1 9KSN LEU A 37  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -3  37  
1 9KSN ARG A 38  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -2  38  
1 9KSN ARG A 39  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -1  39  
1 9KSN GLN A 40  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        0   40  
1 9KSN TYR A 119 ? UNP A0A1Y3PXT7 ARG 79  conflict                79  41  
1 9KSN LEU A 169 ? UNP A0A1Y3PXT7 TRP 129 conflict                129 42  
1 9KSN LEU A 170 ? UNP A0A1Y3PXT7 ASP 130 conflict                130 43  
1 9KSN CYS A 174 ? UNP A0A1Y3PXT7 ASP 134 conflict                134 44  
1 9KSN VAL A 194 ? UNP A0A1Y3PXT7 PHE 154 conflict                154 45  
1 9KSN SER A 201 ? UNP A0A1Y3PXT7 GLY 161 conflict                161 46  
1 9KSN ALA A 202 ? UNP A0A1Y3PXT7 HIS 162 conflict                162 47  
1 9KSN ALA A 217 ? UNP A0A1Y3PXT7 SER 177 conflict                177 48  
1 9KSN ILE A 219 ? UNP A0A1Y3PXT7 THR 179 conflict                179 49  
1 9KSN LEU A 253 ? UNP A0A1Y3PXT7 TYR 213 conflict                213 50  
1 9KSN ILE A 275 ? UNP A0A1Y3PXT7 HIS 235 conflict                235 51  
1 9KSN ALA A 276 ? UNP A0A1Y3PXT7 GLY 236 conflict                236 52  
2 9KSN MET B 1   ? UNP A0A1Y3PXT7 ?   ?   'initiating methionine' -39 53  
2 9KSN GLY B 2   ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -38 54  
2 9KSN SER B 3   ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -37 55  
2 9KSN SER B 4   ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -36 56  
2 9KSN HIS B 5   ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -35 57  
2 9KSN HIS B 6   ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -34 58  
2 9KSN HIS B 7   ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -33 59  
2 9KSN HIS B 8   ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -32 60  
2 9KSN HIS B 9   ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -31 61  
2 9KSN HIS B 10  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -30 62  
2 9KSN SER B 11  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -29 63  
2 9KSN GLY B 12  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -28 64  
2 9KSN ILE B 13  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -27 65  
2 9KSN VAL B 14  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -26 66  
2 9KSN PRO B 15  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -25 67  
2 9KSN ARG B 16  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -24 68  
2 9KSN GLY B 17  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -23 69  
2 9KSN SER B 18  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -22 70  
2 9KSN HIS B 19  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -21 71  
2 9KSN MET B 20  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -20 72  
2 9KSN ALA B 21  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -19 73  
2 9KSN SER B 22  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -18 74  
2 9KSN MET B 23  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -17 75  
2 9KSN THR B 24  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -16 76  
2 9KSN GLY B 25  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -15 77  
2 9KSN GLY B 26  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -14 78  
2 9KSN GLY B 27  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -13 79  
2 9KSN GLN B 28  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -12 80  
2 9KSN MET B 29  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -11 81  
2 9KSN GLY B 30  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -10 82  
2 9KSN ARG B 31  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -9  83  
2 9KSN GLY B 32  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -8  84  
2 9KSN SER B 33  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -7  85  
2 9KSN GLU B 34  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -6  86  
2 9KSN PHE B 35  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -5  87  
2 9KSN GLU B 36  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -4  88  
2 9KSN LEU B 37  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -3  89  
2 9KSN ARG B 38  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -2  90  
2 9KSN ARG B 39  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -1  91  
2 9KSN GLN B 40  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        0   92  
2 9KSN TYR B 119 ? UNP A0A1Y3PXT7 ARG 79  conflict                79  93  
2 9KSN LEU B 169 ? UNP A0A1Y3PXT7 TRP 129 conflict                129 94  
2 9KSN LEU B 170 ? UNP A0A1Y3PXT7 ASP 130 conflict                130 95  
2 9KSN CYS B 174 ? UNP A0A1Y3PXT7 ASP 134 conflict                134 96  
2 9KSN VAL B 194 ? UNP A0A1Y3PXT7 PHE 154 conflict                154 97  
2 9KSN SER B 201 ? UNP A0A1Y3PXT7 GLY 161 conflict                161 98  
2 9KSN ALA B 202 ? UNP A0A1Y3PXT7 HIS 162 conflict                162 99  
2 9KSN ALA B 217 ? UNP A0A1Y3PXT7 SER 177 conflict                177 100 
2 9KSN ILE B 219 ? UNP A0A1Y3PXT7 THR 179 conflict                179 101 
2 9KSN LEU B 253 ? UNP A0A1Y3PXT7 TYR 213 conflict                213 102 
2 9KSN ILE B 275 ? UNP A0A1Y3PXT7 HIS 235 conflict                235 103 
2 9KSN ALA B 276 ? UNP A0A1Y3PXT7 GLY 236 conflict                236 104 
3 9KSN MET C 1   ? UNP A0A1Y3PXT7 ?   ?   'initiating methionine' -39 105 
3 9KSN GLY C 2   ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -38 106 
3 9KSN SER C 3   ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -37 107 
3 9KSN SER C 4   ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -36 108 
3 9KSN HIS C 5   ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -35 109 
3 9KSN HIS C 6   ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -34 110 
3 9KSN HIS C 7   ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -33 111 
3 9KSN HIS C 8   ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -32 112 
3 9KSN HIS C 9   ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -31 113 
3 9KSN HIS C 10  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -30 114 
3 9KSN SER C 11  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -29 115 
3 9KSN GLY C 12  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -28 116 
3 9KSN ILE C 13  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -27 117 
3 9KSN VAL C 14  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -26 118 
3 9KSN PRO C 15  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -25 119 
3 9KSN ARG C 16  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -24 120 
3 9KSN GLY C 17  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -23 121 
3 9KSN SER C 18  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -22 122 
3 9KSN HIS C 19  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -21 123 
3 9KSN MET C 20  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -20 124 
3 9KSN ALA C 21  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -19 125 
3 9KSN SER C 22  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -18 126 
3 9KSN MET C 23  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -17 127 
3 9KSN THR C 24  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -16 128 
3 9KSN GLY C 25  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -15 129 
3 9KSN GLY C 26  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -14 130 
3 9KSN GLY C 27  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -13 131 
3 9KSN GLN C 28  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -12 132 
3 9KSN MET C 29  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -11 133 
3 9KSN GLY C 30  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -10 134 
3 9KSN ARG C 31  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -9  135 
3 9KSN GLY C 32  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -8  136 
3 9KSN SER C 33  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -7  137 
3 9KSN GLU C 34  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -6  138 
3 9KSN PHE C 35  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -5  139 
3 9KSN GLU C 36  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -4  140 
3 9KSN LEU C 37  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -3  141 
3 9KSN ARG C 38  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -2  142 
3 9KSN ARG C 39  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        -1  143 
3 9KSN GLN C 40  ? UNP A0A1Y3PXT7 ?   ?   'expression tag'        0   144 
3 9KSN TYR C 119 ? UNP A0A1Y3PXT7 ARG 79  conflict                79  145 
3 9KSN LEU C 169 ? UNP A0A1Y3PXT7 TRP 129 conflict                129 146 
3 9KSN LEU C 170 ? UNP A0A1Y3PXT7 ASP 130 conflict                130 147 
3 9KSN CYS C 174 ? UNP A0A1Y3PXT7 ASP 134 conflict                134 148 
3 9KSN VAL C 194 ? UNP A0A1Y3PXT7 PHE 154 conflict                154 149 
3 9KSN SER C 201 ? UNP A0A1Y3PXT7 GLY 161 conflict                161 150 
3 9KSN ALA C 202 ? UNP A0A1Y3PXT7 HIS 162 conflict                162 151 
3 9KSN ALA C 217 ? UNP A0A1Y3PXT7 SER 177 conflict                177 152 
3 9KSN ILE C 219 ? UNP A0A1Y3PXT7 THR 179 conflict                179 153 
3 9KSN LEU C 253 ? UNP A0A1Y3PXT7 TYR 213 conflict                213 154 
3 9KSN ILE C 275 ? UNP A0A1Y3PXT7 HIS 235 conflict                235 155 
3 9KSN ALA C 276 ? UNP A0A1Y3PXT7 GLY 236 conflict                236 156 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_defined_assembly ? monomeric 1 
2 author_defined_assembly ? monomeric 1 
3 author_defined_assembly ? monomeric 1 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,D,E,F,G,S       
2 1 B,H,I,J,K,L,M,N,T 
3 1 C,O,P,Q,R,U       
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLY A 58  ? ALA A 71  ? GLY A 18  ALA A 31  1 ? 14 
HELX_P HELX_P2  AA2 ARG A 82  ? GLU A 87  ? ARG A 42  GLU A 47  1 ? 6  
HELX_P HELX_P3  AA3 PRO A 91  ? HIS A 95  ? PRO A 51  HIS A 55  5 ? 5  
HELX_P HELX_P4  AA4 ASP A 102 ? GLY A 107 ? ASP A 62  GLY A 67  5 ? 6  
HELX_P HELX_P5  AA5 PRO A 117 ? TYR A 119 ? PRO A 77  TYR A 79  5 ? 3  
HELX_P HELX_P6  AA6 GLU A 120 ? ARG A 131 ? GLU A 80  ARG A 91  1 ? 12 
HELX_P HELX_P7  AA7 ILE A 141 ? GLN A 143 ? ILE A 101 GLN A 103 5 ? 3  
HELX_P HELX_P8  AA8 GLU A 144 ? HIS A 159 ? GLU A 104 HIS A 119 1 ? 16 
HELX_P HELX_P9  AA9 GLY A 172 ? ALA A 185 ? GLY A 132 ALA A 145 1 ? 14 
HELX_P HELX_P10 AB1 SER A 199 ? ALA A 208 ? SER A 159 ALA A 168 1 ? 10 
HELX_P HELX_P11 AB2 ASP A 240 ? LEU A 249 ? ASP A 200 LEU A 209 1 ? 10 
HELX_P HELX_P12 AB3 ASP A 266 ? ILE A 271 ? ASP A 226 ILE A 231 5 ? 6  
HELX_P HELX_P13 AB4 ASN A 301 ? MET A 317 ? ASN A 261 MET A 277 1 ? 17 
HELX_P HELX_P14 AB5 THR A 325 ? ILE A 329 ? THR A 285 ILE A 289 5 ? 5  
HELX_P HELX_P15 AB6 PRO A 330 ? LEU A 335 ? PRO A 290 LEU A 295 5 ? 6  
HELX_P HELX_P16 AB7 ASP A 338 ? VAL A 347 ? ASP A 298 VAL A 307 1 ? 10 
HELX_P HELX_P17 AB8 GLY B 58  ? ALA B 71  ? GLY B 18  ALA B 31  1 ? 14 
HELX_P HELX_P18 AB9 ARG B 82  ? GLU B 87  ? ARG B 42  GLU B 47  1 ? 6  
HELX_P HELX_P19 AC1 PRO B 91  ? HIS B 95  ? PRO B 51  HIS B 55  5 ? 5  
HELX_P HELX_P20 AC2 ASP B 102 ? GLY B 107 ? ASP B 62  GLY B 67  5 ? 6  
HELX_P HELX_P21 AC3 PRO B 117 ? TYR B 119 ? PRO B 77  TYR B 79  5 ? 3  
HELX_P HELX_P22 AC4 GLU B 120 ? ARG B 131 ? GLU B 80  ARG B 91  1 ? 12 
HELX_P HELX_P23 AC5 ILE B 141 ? GLN B 143 ? ILE B 101 GLN B 103 5 ? 3  
HELX_P HELX_P24 AC6 GLU B 144 ? HIS B 159 ? GLU B 104 HIS B 119 1 ? 16 
HELX_P HELX_P25 AC7 GLY B 172 ? ALA B 185 ? GLY B 132 ALA B 145 1 ? 14 
HELX_P HELX_P26 AC8 SER B 199 ? ALA B 208 ? SER B 159 ALA B 168 1 ? 10 
HELX_P HELX_P27 AC9 ASP B 240 ? LEU B 249 ? ASP B 200 LEU B 209 1 ? 10 
HELX_P HELX_P28 AD1 ASP B 251 ? VAL B 255 ? ASP B 211 VAL B 215 5 ? 5  
HELX_P HELX_P29 AD2 ASP B 266 ? ILE B 271 ? ASP B 226 ILE B 231 5 ? 6  
HELX_P HELX_P30 AD3 ASN B 301 ? MET B 317 ? ASN B 261 MET B 277 1 ? 17 
HELX_P HELX_P31 AD4 THR B 325 ? ILE B 329 ? THR B 285 ILE B 289 5 ? 5  
HELX_P HELX_P32 AD5 PRO B 330 ? LEU B 335 ? PRO B 290 LEU B 295 5 ? 6  
HELX_P HELX_P33 AD6 ASP B 338 ? VAL B 347 ? ASP B 298 VAL B 307 1 ? 10 
HELX_P HELX_P34 AD7 GLY C 58  ? ALA C 71  ? GLY C 18  ALA C 31  1 ? 14 
HELX_P HELX_P35 AD8 ARG C 82  ? GLU C 87  ? ARG C 42  GLU C 47  1 ? 6  
HELX_P HELX_P36 AD9 PRO C 91  ? HIS C 95  ? PRO C 51  HIS C 55  5 ? 5  
HELX_P HELX_P37 AE1 ASP C 102 ? GLY C 107 ? ASP C 62  GLY C 67  5 ? 6  
HELX_P HELX_P38 AE2 PRO C 117 ? TYR C 119 ? PRO C 77  TYR C 79  5 ? 3  
HELX_P HELX_P39 AE3 GLU C 120 ? ALA C 130 ? GLU C 80  ALA C 90  1 ? 11 
HELX_P HELX_P40 AE4 ILE C 141 ? GLN C 143 ? ILE C 101 GLN C 103 5 ? 3  
HELX_P HELX_P41 AE5 GLU C 144 ? HIS C 159 ? GLU C 104 HIS C 119 1 ? 16 
HELX_P HELX_P42 AE6 GLY C 172 ? ALA C 185 ? GLY C 132 ALA C 145 1 ? 14 
HELX_P HELX_P43 AE7 SER C 201 ? VAL C 206 ? SER C 161 VAL C 166 1 ? 6  
HELX_P HELX_P44 AE8 ASP C 240 ? LEU C 249 ? ASP C 200 LEU C 209 1 ? 10 
HELX_P HELX_P45 AE9 ASP C 251 ? VAL C 255 ? ASP C 211 VAL C 215 5 ? 5  
HELX_P HELX_P46 AF1 ASP C 266 ? ILE C 271 ? ASP C 226 ILE C 231 5 ? 6  
HELX_P HELX_P47 AF2 ASN C 301 ? MET C 317 ? ASN C 261 MET C 277 1 ? 17 
HELX_P HELX_P48 AF3 THR C 325 ? ILE C 329 ? THR C 285 ILE C 289 5 ? 5  
HELX_P HELX_P49 AF4 PRO C 330 ? LEU C 335 ? PRO C 290 LEU C 295 5 ? 6  
HELX_P HELX_P50 AF5 ASP C 338 ? VAL C 347 ? ASP C 298 VAL C 307 1 ? 10 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 LEU 170 A . ? LEU 130 A PRO 171 A ? PRO 131 A 1 3.69 
2 LEU 170 B . ? LEU 130 B PRO 171 B ? PRO 131 B 1 3.73 
3 LEU 170 C . ? LEU 130 C PRO 171 C ? PRO 131 C 1 3.95 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 7 ? 
AA2 ? 6 ? 
AA3 ? 4 ? 
AA4 ? 7 ? 
AA5 ? 3 ? 
AA6 ? 4 ? 
AA7 ? 7 ? 
AA8 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA1 6 7 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA2 5 6 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? parallel      
AA4 1 2 ? parallel      
AA4 2 3 ? parallel      
AA4 3 4 ? parallel      
AA4 4 5 ? parallel      
AA4 5 6 ? parallel      
AA4 6 7 ? parallel      
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? parallel      
AA7 1 2 ? parallel      
AA7 2 3 ? parallel      
AA7 3 4 ? parallel      
AA7 4 5 ? parallel      
AA7 5 6 ? parallel      
AA7 6 7 ? parallel      
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 VAL A 99  ? VAL A 100 ? VAL A 59  VAL A 60  
AA1 2 MET A 74  ? VAL A 80  ? MET A 34  VAL A 40  
AA1 3 ILE A 50  ? ILE A 55  ? ILE A 10  ILE A 15  
AA1 4 VAL A 111 ? LEU A 114 ? VAL A 71  LEU A 74  
AA1 5 HIS A 134 ? ASP A 137 ? HIS A 94  ASP A 97  
AA1 6 VAL A 162 ? ILE A 164 ? VAL A 122 ILE A 124 
AA1 7 GLY A 322 ? TYR A 324 ? GLY A 282 TYR A 284 
AA2 1 TYR A 187 ? VAL A 194 ? TYR A 147 VAL A 154 
AA2 2 GLY A 274 ? SER A 285 ? GLY A 234 SER A 245 
AA2 3 THR A 288 ? ASN A 300 ? THR A 248 ASN A 260 
AA2 4 THR C 288 ? ASN C 300 ? THR C 248 ASN C 260 
AA2 5 GLY C 274 ? SER C 285 ? GLY C 234 SER C 245 
AA2 6 TYR C 187 ? VAL C 194 ? TYR C 147 VAL C 154 
AA3 1 GLY A 197 ? MET A 198 ? GLY A 157 MET A 158 
AA3 2 VAL A 212 ? GLY A 223 ? VAL A 172 GLY A 183 
AA3 3 LEU A 226 ? LEU A 235 ? LEU A 186 LEU A 195 
AA3 4 THR A 259 ? GLN A 263 ? THR A 219 GLN A 223 
AA4 1 VAL B 99  ? VAL B 100 ? VAL B 59  VAL B 60  
AA4 2 MET B 74  ? VAL B 80  ? MET B 34  VAL B 40  
AA4 3 ILE B 50  ? ILE B 55  ? ILE B 10  ILE B 15  
AA4 4 VAL B 111 ? LEU B 114 ? VAL B 71  LEU B 74  
AA4 5 HIS B 134 ? ILE B 136 ? HIS B 94  ILE B 96  
AA4 6 VAL B 162 ? ILE B 164 ? VAL B 122 ILE B 124 
AA4 7 GLY B 322 ? TYR B 324 ? GLY B 282 TYR B 284 
AA5 1 TYR B 187 ? VAL B 194 ? TYR B 147 VAL B 154 
AA5 2 GLY B 274 ? SER B 285 ? GLY B 234 SER B 245 
AA5 3 THR B 288 ? ASN B 300 ? THR B 248 ASN B 260 
AA6 1 GLY B 197 ? MET B 198 ? GLY B 157 MET B 158 
AA6 2 VAL B 212 ? GLY B 223 ? VAL B 172 GLY B 183 
AA6 3 LEU B 226 ? LEU B 235 ? LEU B 186 LEU B 195 
AA6 4 THR B 259 ? GLN B 263 ? THR B 219 GLN B 223 
AA7 1 VAL C 99  ? VAL C 100 ? VAL C 59  VAL C 60  
AA7 2 MET C 74  ? VAL C 80  ? MET C 34  VAL C 40  
AA7 3 ILE C 50  ? ILE C 55  ? ILE C 10  ILE C 15  
AA7 4 VAL C 111 ? LEU C 114 ? VAL C 71  LEU C 74  
AA7 5 HIS C 134 ? ILE C 136 ? HIS C 94  ILE C 96  
AA7 6 VAL C 162 ? ILE C 164 ? VAL C 122 ILE C 124 
AA7 7 GLY C 322 ? TYR C 324 ? GLY C 282 TYR C 284 
AA8 1 GLY C 197 ? MET C 198 ? GLY C 157 MET C 158 
AA8 2 ALA C 215 ? GLY C 223 ? ALA C 175 GLY C 183 
AA8 3 LEU C 226 ? VAL C 233 ? LEU C 186 VAL C 193 
AA8 4 THR C 259 ? GLN C 263 ? THR C 219 GLN C 223 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O VAL A 100 ? O VAL A 60  N VAL A 79  ? N VAL A 39  
AA1 2 3 O ALA A 77  ? O ALA A 37  N VAL A 52  ? N VAL A 12  
AA1 3 4 N ALA A 53  ? N ALA A 13  O VAL A 113 ? O VAL A 73  
AA1 4 5 N LEU A 114 ? N LEU A 74  O ILE A 136 ? O ILE A 96  
AA1 5 6 N THR A 135 ? N THR A 95  O ILE A 164 ? O ILE A 124 
AA1 6 7 N ALA A 163 ? N ALA A 123 O TYR A 324 ? O TYR A 284 
AA2 1 2 N ASN A 193 ? N ASN A 153 O ARG A 278 ? O ARG A 238 
AA2 2 3 N MET A 279 ? N MET A 239 O TYR A 295 ? O TYR A 255 
AA2 3 4 N GLU A 296 ? N GLU A 256 O THR C 294 ? O THR C 254 
AA2 4 5 O TYR C 295 ? O TYR C 255 N MET C 279 ? N MET C 239 
AA2 5 6 O ARG C 278 ? O ARG C 238 N ASN C 193 ? N ASN C 153 
AA3 1 2 N GLY A 197 ? N GLY A 157 O ILE A 219 ? O ILE A 179 
AA3 2 3 N ILE A 220 ? N ILE A 180 O ARG A 228 ? O ARG A 188 
AA3 3 4 N VAL A 231 ? N VAL A 191 O HIS A 260 ? O HIS A 220 
AA4 1 2 O VAL B 100 ? O VAL B 60  N VAL B 79  ? N VAL B 39  
AA4 2 3 O ALA B 77  ? O ALA B 37  N VAL B 52  ? N VAL B 12  
AA4 3 4 N ALA B 53  ? N ALA B 13  O VAL B 113 ? O VAL B 73  
AA4 4 5 N LEU B 114 ? N LEU B 74  O ILE B 136 ? O ILE B 96  
AA4 5 6 N THR B 135 ? N THR B 95  O ILE B 164 ? O ILE B 124 
AA4 6 7 N ALA B 163 ? N ALA B 123 O GLY B 322 ? O GLY B 282 
AA5 1 2 N ASN B 193 ? N ASN B 153 O ARG B 278 ? O ARG B 238 
AA5 2 3 N MET B 279 ? N MET B 239 O TYR B 295 ? O TYR B 255 
AA6 1 2 N GLY B 197 ? N GLY B 157 O ILE B 219 ? O ILE B 179 
AA6 2 3 N ASP B 214 ? N ASP B 174 O GLU B 234 ? O GLU B 194 
AA6 3 4 N VAL B 231 ? N VAL B 191 O HIS B 260 ? O HIS B 220 
AA7 1 2 O VAL C 100 ? O VAL C 60  N VAL C 79  ? N VAL C 39  
AA7 2 3 O ALA C 77  ? O ALA C 37  N VAL C 52  ? N VAL C 12  
AA7 3 4 N ALA C 53  ? N ALA C 13  O VAL C 113 ? O VAL C 73  
AA7 4 5 N LEU C 114 ? N LEU C 74  O ILE C 136 ? O ILE C 96  
AA7 5 6 N THR C 135 ? N THR C 95  O ILE C 164 ? O ILE C 124 
AA7 6 7 N ALA C 163 ? N ALA C 123 O TYR C 324 ? O TYR C 284 
AA8 1 2 N GLY C 197 ? N GLY C 157 O ILE C 219 ? O ILE C 179 
AA8 2 3 N ILE C 220 ? N ILE C 180 O ARG C 228 ? O ARG C 188 
AA8 3 4 N VAL C 231 ? N VAL C 191 O HIS C 260 ? O HIS C 220 
# 
_pdbx_entry_details.entry_id                   9KSN 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 OG1 A THR 150 ? ? O   A HOH 501 ? ? 2.10 
2 1 OG  B SER 266 ? ? O   B HOH 501 ? ? 2.14 
3 1 O   B HOH 509 ? ? O   B HOH 514 ? ? 2.15 
4 1 O   A ARG 274 ? ? O   A HOH 502 ? ? 2.16 
5 1 NH1 C ARG 238 ? ? OE1 C GLU 256 ? ? 2.18 
6 1 NZ  C LYS 86  ? ? O   C HOH 501 ? ? 2.18 
# 
_pdbx_validate_symm_contact.id                1 
_pdbx_validate_symm_contact.PDB_model_num     1 
_pdbx_validate_symm_contact.auth_atom_id_1    O 
_pdbx_validate_symm_contact.auth_asym_id_1    B 
_pdbx_validate_symm_contact.auth_comp_id_1    HOH 
_pdbx_validate_symm_contact.auth_seq_id_1     509 
_pdbx_validate_symm_contact.PDB_ins_code_1    ? 
_pdbx_validate_symm_contact.label_alt_id_1    ? 
_pdbx_validate_symm_contact.site_symmetry_1   1_555 
_pdbx_validate_symm_contact.auth_atom_id_2    O 
_pdbx_validate_symm_contact.auth_asym_id_2    C 
_pdbx_validate_symm_contact.auth_comp_id_2    HOH 
_pdbx_validate_symm_contact.auth_seq_id_2     512 
_pdbx_validate_symm_contact.PDB_ins_code_2    ? 
_pdbx_validate_symm_contact.label_alt_id_2    ? 
_pdbx_validate_symm_contact.site_symmetry_2   6_545 
_pdbx_validate_symm_contact.dist              1.87 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 GLU A 7   ? ? -62.26  -80.79 
2  1 TYR A 17  ? ? -108.33 72.40  
3  1 CYS A 75  ? ? -108.03 46.67  
4  1 ALA A 127 ? ? -104.12 70.53  
5  1 TYR B 17  ? ? -108.37 72.86  
6  1 CYS B 75  ? ? -108.76 46.16  
7  1 ALA B 127 ? ? -104.81 72.05  
8  1 TYR C 17  ? ? -110.12 75.24  
9  1 CYS C 75  ? ? -108.67 46.88  
10 1 ALA C 127 ? ? -103.51 70.82  
11 1 VAL C 166 ? ? -66.18  99.85  
12 1 LYS C 167 ? ? -127.09 -62.31 
13 1 GLU C 170 ? ? 65.25   -25.66 
14 1 GLU C 206 ? ? -85.06  31.14  
# 
_pdbx_validate_peptide_omega.id               1 
_pdbx_validate_peptide_omega.PDB_model_num    1 
_pdbx_validate_peptide_omega.auth_comp_id_1   GLY 
_pdbx_validate_peptide_omega.auth_asym_id_1   C 
_pdbx_validate_peptide_omega.auth_seq_id_1    171 
_pdbx_validate_peptide_omega.PDB_ins_code_1   ? 
_pdbx_validate_peptide_omega.label_alt_id_1   ? 
_pdbx_validate_peptide_omega.auth_comp_id_2   VAL 
_pdbx_validate_peptide_omega.auth_asym_id_2   C 
_pdbx_validate_peptide_omega.auth_seq_id_2    172 
_pdbx_validate_peptide_omega.PDB_ins_code_2   ? 
_pdbx_validate_peptide_omega.label_alt_id_2   ? 
_pdbx_validate_peptide_omega.omega            147.08 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z               
2 -y+1/2,x+1/2,z+3/4  
3 y+1/2,-x+1/2,z+1/4  
4 x+1/2,-y+1/2,-z+1/4 
5 -x+1/2,y+1/2,-z+3/4 
6 -x,-y,z+1/2         
7 y,x,-z              
8 -y,-x,-z+1/2        
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET -39 ? A MET 1   
2   1 Y 1 A GLY -38 ? A GLY 2   
3   1 Y 1 A SER -37 ? A SER 3   
4   1 Y 1 A SER -36 ? A SER 4   
5   1 Y 1 A HIS -35 ? A HIS 5   
6   1 Y 1 A HIS -34 ? A HIS 6   
7   1 Y 1 A HIS -33 ? A HIS 7   
8   1 Y 1 A HIS -32 ? A HIS 8   
9   1 Y 1 A HIS -31 ? A HIS 9   
10  1 Y 1 A HIS -30 ? A HIS 10  
11  1 Y 1 A SER -29 ? A SER 11  
12  1 Y 1 A GLY -28 ? A GLY 12  
13  1 Y 1 A ILE -27 ? A ILE 13  
14  1 Y 1 A VAL -26 ? A VAL 14  
15  1 Y 1 A PRO -25 ? A PRO 15  
16  1 Y 1 A ARG -24 ? A ARG 16  
17  1 Y 1 A GLY -23 ? A GLY 17  
18  1 Y 1 A SER -22 ? A SER 18  
19  1 Y 1 A HIS -21 ? A HIS 19  
20  1 Y 1 A MET -20 ? A MET 20  
21  1 Y 1 A ALA -19 ? A ALA 21  
22  1 Y 1 A SER -18 ? A SER 22  
23  1 Y 1 A MET -17 ? A MET 23  
24  1 Y 1 A THR -16 ? A THR 24  
25  1 Y 1 A GLY -15 ? A GLY 25  
26  1 Y 1 A GLY -14 ? A GLY 26  
27  1 Y 1 A GLY -13 ? A GLY 27  
28  1 Y 1 A GLN -12 ? A GLN 28  
29  1 Y 1 A MET -11 ? A MET 29  
30  1 Y 1 A GLY -10 ? A GLY 30  
31  1 Y 1 A ARG -9  ? A ARG 31  
32  1 Y 1 A GLY -8  ? A GLY 32  
33  1 Y 1 A SER -7  ? A SER 33  
34  1 Y 1 A GLU -6  ? A GLU 34  
35  1 Y 1 A PHE -5  ? A PHE 35  
36  1 Y 1 A GLU -4  ? A GLU 36  
37  1 Y 1 A LEU -3  ? A LEU 37  
38  1 Y 1 A ARG -2  ? A ARG 38  
39  1 Y 1 A ARG -1  ? A ARG 39  
40  1 Y 1 A GLN 0   ? A GLN 40  
41  1 Y 1 A MET 1   ? A MET 41  
42  1 Y 1 A SER 2   ? A SER 42  
43  1 Y 1 A GLU 3   ? A GLU 43  
44  1 Y 1 A ILE 4   ? A ILE 44  
45  1 Y 1 B MET -39 ? B MET 1   
46  1 Y 1 B GLY -38 ? B GLY 2   
47  1 Y 1 B SER -37 ? B SER 3   
48  1 Y 1 B SER -36 ? B SER 4   
49  1 Y 1 B HIS -35 ? B HIS 5   
50  1 Y 1 B HIS -34 ? B HIS 6   
51  1 Y 1 B HIS -33 ? B HIS 7   
52  1 Y 1 B HIS -32 ? B HIS 8   
53  1 Y 1 B HIS -31 ? B HIS 9   
54  1 Y 1 B HIS -30 ? B HIS 10  
55  1 Y 1 B SER -29 ? B SER 11  
56  1 Y 1 B GLY -28 ? B GLY 12  
57  1 Y 1 B ILE -27 ? B ILE 13  
58  1 Y 1 B VAL -26 ? B VAL 14  
59  1 Y 1 B PRO -25 ? B PRO 15  
60  1 Y 1 B ARG -24 ? B ARG 16  
61  1 Y 1 B GLY -23 ? B GLY 17  
62  1 Y 1 B SER -22 ? B SER 18  
63  1 Y 1 B HIS -21 ? B HIS 19  
64  1 Y 1 B MET -20 ? B MET 20  
65  1 Y 1 B ALA -19 ? B ALA 21  
66  1 Y 1 B SER -18 ? B SER 22  
67  1 Y 1 B MET -17 ? B MET 23  
68  1 Y 1 B THR -16 ? B THR 24  
69  1 Y 1 B GLY -15 ? B GLY 25  
70  1 Y 1 B GLY -14 ? B GLY 26  
71  1 Y 1 B GLY -13 ? B GLY 27  
72  1 Y 1 B GLN -12 ? B GLN 28  
73  1 Y 1 B MET -11 ? B MET 29  
74  1 Y 1 B GLY -10 ? B GLY 30  
75  1 Y 1 B ARG -9  ? B ARG 31  
76  1 Y 1 B GLY -8  ? B GLY 32  
77  1 Y 1 B SER -7  ? B SER 33  
78  1 Y 1 B GLU -6  ? B GLU 34  
79  1 Y 1 B PHE -5  ? B PHE 35  
80  1 Y 1 B GLU -4  ? B GLU 36  
81  1 Y 1 B LEU -3  ? B LEU 37  
82  1 Y 1 B ARG -2  ? B ARG 38  
83  1 Y 1 B ARG -1  ? B ARG 39  
84  1 Y 1 B GLN 0   ? B GLN 40  
85  1 Y 1 B MET 1   ? B MET 41  
86  1 Y 1 C MET -39 ? C MET 1   
87  1 Y 1 C GLY -38 ? C GLY 2   
88  1 Y 1 C SER -37 ? C SER 3   
89  1 Y 1 C SER -36 ? C SER 4   
90  1 Y 1 C HIS -35 ? C HIS 5   
91  1 Y 1 C HIS -34 ? C HIS 6   
92  1 Y 1 C HIS -33 ? C HIS 7   
93  1 Y 1 C HIS -32 ? C HIS 8   
94  1 Y 1 C HIS -31 ? C HIS 9   
95  1 Y 1 C HIS -30 ? C HIS 10  
96  1 Y 1 C SER -29 ? C SER 11  
97  1 Y 1 C GLY -28 ? C GLY 12  
98  1 Y 1 C ILE -27 ? C ILE 13  
99  1 Y 1 C VAL -26 ? C VAL 14  
100 1 Y 1 C PRO -25 ? C PRO 15  
101 1 Y 1 C ARG -24 ? C ARG 16  
102 1 Y 1 C GLY -23 ? C GLY 17  
103 1 Y 1 C SER -22 ? C SER 18  
104 1 Y 1 C HIS -21 ? C HIS 19  
105 1 Y 1 C MET -20 ? C MET 20  
106 1 Y 1 C ALA -19 ? C ALA 21  
107 1 Y 1 C SER -18 ? C SER 22  
108 1 Y 1 C MET -17 ? C MET 23  
109 1 Y 1 C THR -16 ? C THR 24  
110 1 Y 1 C GLY -15 ? C GLY 25  
111 1 Y 1 C GLY -14 ? C GLY 26  
112 1 Y 1 C GLY -13 ? C GLY 27  
113 1 Y 1 C GLN -12 ? C GLN 28  
114 1 Y 1 C MET -11 ? C MET 29  
115 1 Y 1 C GLY -10 ? C GLY 30  
116 1 Y 1 C ARG -9  ? C ARG 31  
117 1 Y 1 C GLY -8  ? C GLY 32  
118 1 Y 1 C SER -7  ? C SER 33  
119 1 Y 1 C GLU -6  ? C GLU 34  
120 1 Y 1 C PHE -5  ? C PHE 35  
121 1 Y 1 C GLU -4  ? C GLU 36  
122 1 Y 1 C LEU -3  ? C LEU 37  
123 1 Y 1 C ARG -2  ? C ARG 38  
124 1 Y 1 C ARG -1  ? C ARG 39  
125 1 Y 1 C GLN 0   ? C GLN 40  
126 1 Y 1 C MET 1   ? C MET 41  
127 1 Y 1 C GLU 196 ? C GLU 236 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ACY C    C N N 1   
ACY O    O N N 2   
ACY OXT  O N N 3   
ACY CH3  C N N 4   
ACY HXT  H N N 5   
ACY H1   H N N 6   
ACY H2   H N N 7   
ACY H3   H N N 8   
ALA N    N N N 9   
ALA CA   C N S 10  
ALA C    C N N 11  
ALA O    O N N 12  
ALA CB   C N N 13  
ALA OXT  O N N 14  
ALA H    H N N 15  
ALA H2   H N N 16  
ALA HA   H N N 17  
ALA HB1  H N N 18  
ALA HB2  H N N 19  
ALA HB3  H N N 20  
ALA HXT  H N N 21  
ARG N    N N N 22  
ARG CA   C N S 23  
ARG C    C N N 24  
ARG O    O N N 25  
ARG CB   C N N 26  
ARG CG   C N N 27  
ARG CD   C N N 28  
ARG NE   N N N 29  
ARG CZ   C N N 30  
ARG NH1  N N N 31  
ARG NH2  N N N 32  
ARG OXT  O N N 33  
ARG H    H N N 34  
ARG H2   H N N 35  
ARG HA   H N N 36  
ARG HB2  H N N 37  
ARG HB3  H N N 38  
ARG HG2  H N N 39  
ARG HG3  H N N 40  
ARG HD2  H N N 41  
ARG HD3  H N N 42  
ARG HE   H N N 43  
ARG HH11 H N N 44  
ARG HH12 H N N 45  
ARG HH21 H N N 46  
ARG HH22 H N N 47  
ARG HXT  H N N 48  
ASN N    N N N 49  
ASN CA   C N S 50  
ASN C    C N N 51  
ASN O    O N N 52  
ASN CB   C N N 53  
ASN CG   C N N 54  
ASN OD1  O N N 55  
ASN ND2  N N N 56  
ASN OXT  O N N 57  
ASN H    H N N 58  
ASN H2   H N N 59  
ASN HA   H N N 60  
ASN HB2  H N N 61  
ASN HB3  H N N 62  
ASN HD21 H N N 63  
ASN HD22 H N N 64  
ASN HXT  H N N 65  
ASP N    N N N 66  
ASP CA   C N S 67  
ASP C    C N N 68  
ASP O    O N N 69  
ASP CB   C N N 70  
ASP CG   C N N 71  
ASP OD1  O N N 72  
ASP OD2  O N N 73  
ASP OXT  O N N 74  
ASP H    H N N 75  
ASP H2   H N N 76  
ASP HA   H N N 77  
ASP HB2  H N N 78  
ASP HB3  H N N 79  
ASP HD2  H N N 80  
ASP HXT  H N N 81  
CYS N    N N N 82  
CYS CA   C N R 83  
CYS C    C N N 84  
CYS O    O N N 85  
CYS CB   C N N 86  
CYS SG   S N N 87  
CYS OXT  O N N 88  
CYS H    H N N 89  
CYS H2   H N N 90  
CYS HA   H N N 91  
CYS HB2  H N N 92  
CYS HB3  H N N 93  
CYS HG   H N N 94  
CYS HXT  H N N 95  
GLN N    N N N 96  
GLN CA   C N S 97  
GLN C    C N N 98  
GLN O    O N N 99  
GLN CB   C N N 100 
GLN CG   C N N 101 
GLN CD   C N N 102 
GLN OE1  O N N 103 
GLN NE2  N N N 104 
GLN OXT  O N N 105 
GLN H    H N N 106 
GLN H2   H N N 107 
GLN HA   H N N 108 
GLN HB2  H N N 109 
GLN HB3  H N N 110 
GLN HG2  H N N 111 
GLN HG3  H N N 112 
GLN HE21 H N N 113 
GLN HE22 H N N 114 
GLN HXT  H N N 115 
GLU N    N N N 116 
GLU CA   C N S 117 
GLU C    C N N 118 
GLU O    O N N 119 
GLU CB   C N N 120 
GLU CG   C N N 121 
GLU CD   C N N 122 
GLU OE1  O N N 123 
GLU OE2  O N N 124 
GLU OXT  O N N 125 
GLU H    H N N 126 
GLU H2   H N N 127 
GLU HA   H N N 128 
GLU HB2  H N N 129 
GLU HB3  H N N 130 
GLU HG2  H N N 131 
GLU HG3  H N N 132 
GLU HE2  H N N 133 
GLU HXT  H N N 134 
GLY N    N N N 135 
GLY CA   C N N 136 
GLY C    C N N 137 
GLY O    O N N 138 
GLY OXT  O N N 139 
GLY H    H N N 140 
GLY H2   H N N 141 
GLY HA2  H N N 142 
GLY HA3  H N N 143 
GLY HXT  H N N 144 
HIS N    N N N 145 
HIS CA   C N S 146 
HIS C    C N N 147 
HIS O    O N N 148 
HIS CB   C N N 149 
HIS CG   C Y N 150 
HIS ND1  N Y N 151 
HIS CD2  C Y N 152 
HIS CE1  C Y N 153 
HIS NE2  N Y N 154 
HIS OXT  O N N 155 
HIS H    H N N 156 
HIS H2   H N N 157 
HIS HA   H N N 158 
HIS HB2  H N N 159 
HIS HB3  H N N 160 
HIS HD1  H N N 161 
HIS HD2  H N N 162 
HIS HE1  H N N 163 
HIS HE2  H N N 164 
HIS HXT  H N N 165 
HOH O    O N N 166 
HOH H1   H N N 167 
HOH H2   H N N 168 
ILE N    N N N 169 
ILE CA   C N S 170 
ILE C    C N N 171 
ILE O    O N N 172 
ILE CB   C N S 173 
ILE CG1  C N N 174 
ILE CG2  C N N 175 
ILE CD1  C N N 176 
ILE OXT  O N N 177 
ILE H    H N N 178 
ILE H2   H N N 179 
ILE HA   H N N 180 
ILE HB   H N N 181 
ILE HG12 H N N 182 
ILE HG13 H N N 183 
ILE HG21 H N N 184 
ILE HG22 H N N 185 
ILE HG23 H N N 186 
ILE HD11 H N N 187 
ILE HD12 H N N 188 
ILE HD13 H N N 189 
ILE HXT  H N N 190 
IMD N1   N Y N 191 
IMD C2   C Y N 192 
IMD N3   N Y N 193 
IMD C4   C Y N 194 
IMD C5   C Y N 195 
IMD HN1  H N N 196 
IMD H2   H N N 197 
IMD HN3  H N N 198 
IMD H4   H N N 199 
IMD H5   H N N 200 
LEU N    N N N 201 
LEU CA   C N S 202 
LEU C    C N N 203 
LEU O    O N N 204 
LEU CB   C N N 205 
LEU CG   C N N 206 
LEU CD1  C N N 207 
LEU CD2  C N N 208 
LEU OXT  O N N 209 
LEU H    H N N 210 
LEU H2   H N N 211 
LEU HA   H N N 212 
LEU HB2  H N N 213 
LEU HB3  H N N 214 
LEU HG   H N N 215 
LEU HD11 H N N 216 
LEU HD12 H N N 217 
LEU HD13 H N N 218 
LEU HD21 H N N 219 
LEU HD22 H N N 220 
LEU HD23 H N N 221 
LEU HXT  H N N 222 
LYS N    N N N 223 
LYS CA   C N S 224 
LYS C    C N N 225 
LYS O    O N N 226 
LYS CB   C N N 227 
LYS CG   C N N 228 
LYS CD   C N N 229 
LYS CE   C N N 230 
LYS NZ   N N N 231 
LYS OXT  O N N 232 
LYS H    H N N 233 
LYS H2   H N N 234 
LYS HA   H N N 235 
LYS HB2  H N N 236 
LYS HB3  H N N 237 
LYS HG2  H N N 238 
LYS HG3  H N N 239 
LYS HD2  H N N 240 
LYS HD3  H N N 241 
LYS HE2  H N N 242 
LYS HE3  H N N 243 
LYS HZ1  H N N 244 
LYS HZ2  H N N 245 
LYS HZ3  H N N 246 
LYS HXT  H N N 247 
MET N    N N N 248 
MET CA   C N S 249 
MET C    C N N 250 
MET O    O N N 251 
MET CB   C N N 252 
MET CG   C N N 253 
MET SD   S N N 254 
MET CE   C N N 255 
MET OXT  O N N 256 
MET H    H N N 257 
MET H2   H N N 258 
MET HA   H N N 259 
MET HB2  H N N 260 
MET HB3  H N N 261 
MET HG2  H N N 262 
MET HG3  H N N 263 
MET HE1  H N N 264 
MET HE2  H N N 265 
MET HE3  H N N 266 
MET HXT  H N N 267 
NAP PA   P N R 268 
NAP O1A  O N N 269 
NAP O2A  O N N 270 
NAP O5B  O N N 271 
NAP C5B  C N N 272 
NAP C4B  C N R 273 
NAP O4B  O N N 274 
NAP C3B  C N R 275 
NAP O3B  O N N 276 
NAP C2B  C N R 277 
NAP O2B  O N N 278 
NAP C1B  C N R 279 
NAP N9A  N Y N 280 
NAP C8A  C Y N 281 
NAP N7A  N Y N 282 
NAP C5A  C Y N 283 
NAP C6A  C Y N 284 
NAP N6A  N N N 285 
NAP N1A  N Y N 286 
NAP C2A  C Y N 287 
NAP N3A  N Y N 288 
NAP C4A  C Y N 289 
NAP O3   O N N 290 
NAP PN   P N N 291 
NAP O1N  O N N 292 
NAP O2N  O N N 293 
NAP O5D  O N N 294 
NAP C5D  C N N 295 
NAP C4D  C N R 296 
NAP O4D  O N N 297 
NAP C3D  C N S 298 
NAP O3D  O N N 299 
NAP C2D  C N R 300 
NAP O2D  O N N 301 
NAP C1D  C N R 302 
NAP N1N  N Y N 303 
NAP C2N  C Y N 304 
NAP C3N  C Y N 305 
NAP C7N  C N N 306 
NAP O7N  O N N 307 
NAP N7N  N N N 308 
NAP C4N  C Y N 309 
NAP C5N  C Y N 310 
NAP C6N  C Y N 311 
NAP P2B  P N N 312 
NAP O1X  O N N 313 
NAP O2X  O N N 314 
NAP O3X  O N N 315 
NAP HOA2 H N N 316 
NAP H51A H N N 317 
NAP H52A H N N 318 
NAP H4B  H N N 319 
NAP H3B  H N N 320 
NAP HO3A H N N 321 
NAP H2B  H N N 322 
NAP H1B  H N N 323 
NAP H8A  H N N 324 
NAP H61A H N N 325 
NAP H62A H N N 326 
NAP H2A  H N N 327 
NAP H51N H N N 328 
NAP H52N H N N 329 
NAP H4D  H N N 330 
NAP H3D  H N N 331 
NAP HO3N H N N 332 
NAP H2D  H N N 333 
NAP HO2N H N N 334 
NAP H1D  H N N 335 
NAP H2N  H N N 336 
NAP H71N H N N 337 
NAP H72N H N N 338 
NAP H4N  H N N 339 
NAP H5N  H N N 340 
NAP H6N  H N N 341 
NAP HOP2 H N N 342 
NAP HOP3 H N N 343 
OXM C1   C N N 344 
OXM N1   N N N 345 
OXM O1   O N N 346 
OXM C2   C N N 347 
OXM O2   O N N 348 
OXM O3   O N N 349 
OXM HN1  H N N 350 
OXM HN2  H N N 351 
OXM HO3  H N N 352 
PHE N    N N N 353 
PHE CA   C N S 354 
PHE C    C N N 355 
PHE O    O N N 356 
PHE CB   C N N 357 
PHE CG   C Y N 358 
PHE CD1  C Y N 359 
PHE CD2  C Y N 360 
PHE CE1  C Y N 361 
PHE CE2  C Y N 362 
PHE CZ   C Y N 363 
PHE OXT  O N N 364 
PHE H    H N N 365 
PHE H2   H N N 366 
PHE HA   H N N 367 
PHE HB2  H N N 368 
PHE HB3  H N N 369 
PHE HD1  H N N 370 
PHE HD2  H N N 371 
PHE HE1  H N N 372 
PHE HE2  H N N 373 
PHE HZ   H N N 374 
PHE HXT  H N N 375 
PRO N    N N N 376 
PRO CA   C N S 377 
PRO C    C N N 378 
PRO O    O N N 379 
PRO CB   C N N 380 
PRO CG   C N N 381 
PRO CD   C N N 382 
PRO OXT  O N N 383 
PRO H    H N N 384 
PRO HA   H N N 385 
PRO HB2  H N N 386 
PRO HB3  H N N 387 
PRO HG2  H N N 388 
PRO HG3  H N N 389 
PRO HD2  H N N 390 
PRO HD3  H N N 391 
PRO HXT  H N N 392 
SER N    N N N 393 
SER CA   C N S 394 
SER C    C N N 395 
SER O    O N N 396 
SER CB   C N N 397 
SER OG   O N N 398 
SER OXT  O N N 399 
SER H    H N N 400 
SER H2   H N N 401 
SER HA   H N N 402 
SER HB2  H N N 403 
SER HB3  H N N 404 
SER HG   H N N 405 
SER HXT  H N N 406 
THR N    N N N 407 
THR CA   C N S 408 
THR C    C N N 409 
THR O    O N N 410 
THR CB   C N R 411 
THR OG1  O N N 412 
THR CG2  C N N 413 
THR OXT  O N N 414 
THR H    H N N 415 
THR H2   H N N 416 
THR HA   H N N 417 
THR HB   H N N 418 
THR HG1  H N N 419 
THR HG21 H N N 420 
THR HG22 H N N 421 
THR HG23 H N N 422 
THR HXT  H N N 423 
TRP N    N N N 424 
TRP CA   C N S 425 
TRP C    C N N 426 
TRP O    O N N 427 
TRP CB   C N N 428 
TRP CG   C Y N 429 
TRP CD1  C Y N 430 
TRP CD2  C Y N 431 
TRP NE1  N Y N 432 
TRP CE2  C Y N 433 
TRP CE3  C Y N 434 
TRP CZ2  C Y N 435 
TRP CZ3  C Y N 436 
TRP CH2  C Y N 437 
TRP OXT  O N N 438 
TRP H    H N N 439 
TRP H2   H N N 440 
TRP HA   H N N 441 
TRP HB2  H N N 442 
TRP HB3  H N N 443 
TRP HD1  H N N 444 
TRP HE1  H N N 445 
TRP HE3  H N N 446 
TRP HZ2  H N N 447 
TRP HZ3  H N N 448 
TRP HH2  H N N 449 
TRP HXT  H N N 450 
TYR N    N N N 451 
TYR CA   C N S 452 
TYR C    C N N 453 
TYR O    O N N 454 
TYR CB   C N N 455 
TYR CG   C Y N 456 
TYR CD1  C Y N 457 
TYR CD2  C Y N 458 
TYR CE1  C Y N 459 
TYR CE2  C Y N 460 
TYR CZ   C Y N 461 
TYR OH   O N N 462 
TYR OXT  O N N 463 
TYR H    H N N 464 
TYR H2   H N N 465 
TYR HA   H N N 466 
TYR HB2  H N N 467 
TYR HB3  H N N 468 
TYR HD1  H N N 469 
TYR HD2  H N N 470 
TYR HE1  H N N 471 
TYR HE2  H N N 472 
TYR HH   H N N 473 
TYR HXT  H N N 474 
VAL N    N N N 475 
VAL CA   C N S 476 
VAL C    C N N 477 
VAL O    O N N 478 
VAL CB   C N N 479 
VAL CG1  C N N 480 
VAL CG2  C N N 481 
VAL OXT  O N N 482 
VAL H    H N N 483 
VAL H2   H N N 484 
VAL HA   H N N 485 
VAL HB   H N N 486 
VAL HG11 H N N 487 
VAL HG12 H N N 488 
VAL HG13 H N N 489 
VAL HG21 H N N 490 
VAL HG22 H N N 491 
VAL HG23 H N N 492 
VAL HXT  H N N 493 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ACY C   O    doub N N 1   
ACY C   OXT  sing N N 2   
ACY C   CH3  sing N N 3   
ACY OXT HXT  sing N N 4   
ACY CH3 H1   sing N N 5   
ACY CH3 H2   sing N N 6   
ACY CH3 H3   sing N N 7   
ALA N   CA   sing N N 8   
ALA N   H    sing N N 9   
ALA N   H2   sing N N 10  
ALA CA  C    sing N N 11  
ALA CA  CB   sing N N 12  
ALA CA  HA   sing N N 13  
ALA C   O    doub N N 14  
ALA C   OXT  sing N N 15  
ALA CB  HB1  sing N N 16  
ALA CB  HB2  sing N N 17  
ALA CB  HB3  sing N N 18  
ALA OXT HXT  sing N N 19  
ARG N   CA   sing N N 20  
ARG N   H    sing N N 21  
ARG N   H2   sing N N 22  
ARG CA  C    sing N N 23  
ARG CA  CB   sing N N 24  
ARG CA  HA   sing N N 25  
ARG C   O    doub N N 26  
ARG C   OXT  sing N N 27  
ARG CB  CG   sing N N 28  
ARG CB  HB2  sing N N 29  
ARG CB  HB3  sing N N 30  
ARG CG  CD   sing N N 31  
ARG CG  HG2  sing N N 32  
ARG CG  HG3  sing N N 33  
ARG CD  NE   sing N N 34  
ARG CD  HD2  sing N N 35  
ARG CD  HD3  sing N N 36  
ARG NE  CZ   sing N N 37  
ARG NE  HE   sing N N 38  
ARG CZ  NH1  sing N N 39  
ARG CZ  NH2  doub N N 40  
ARG NH1 HH11 sing N N 41  
ARG NH1 HH12 sing N N 42  
ARG NH2 HH21 sing N N 43  
ARG NH2 HH22 sing N N 44  
ARG OXT HXT  sing N N 45  
ASN N   CA   sing N N 46  
ASN N   H    sing N N 47  
ASN N   H2   sing N N 48  
ASN CA  C    sing N N 49  
ASN CA  CB   sing N N 50  
ASN CA  HA   sing N N 51  
ASN C   O    doub N N 52  
ASN C   OXT  sing N N 53  
ASN CB  CG   sing N N 54  
ASN CB  HB2  sing N N 55  
ASN CB  HB3  sing N N 56  
ASN CG  OD1  doub N N 57  
ASN CG  ND2  sing N N 58  
ASN ND2 HD21 sing N N 59  
ASN ND2 HD22 sing N N 60  
ASN OXT HXT  sing N N 61  
ASP N   CA   sing N N 62  
ASP N   H    sing N N 63  
ASP N   H2   sing N N 64  
ASP CA  C    sing N N 65  
ASP CA  CB   sing N N 66  
ASP CA  HA   sing N N 67  
ASP C   O    doub N N 68  
ASP C   OXT  sing N N 69  
ASP CB  CG   sing N N 70  
ASP CB  HB2  sing N N 71  
ASP CB  HB3  sing N N 72  
ASP CG  OD1  doub N N 73  
ASP CG  OD2  sing N N 74  
ASP OD2 HD2  sing N N 75  
ASP OXT HXT  sing N N 76  
CYS N   CA   sing N N 77  
CYS N   H    sing N N 78  
CYS N   H2   sing N N 79  
CYS CA  C    sing N N 80  
CYS CA  CB   sing N N 81  
CYS CA  HA   sing N N 82  
CYS C   O    doub N N 83  
CYS C   OXT  sing N N 84  
CYS CB  SG   sing N N 85  
CYS CB  HB2  sing N N 86  
CYS CB  HB3  sing N N 87  
CYS SG  HG   sing N N 88  
CYS OXT HXT  sing N N 89  
GLN N   CA   sing N N 90  
GLN N   H    sing N N 91  
GLN N   H2   sing N N 92  
GLN CA  C    sing N N 93  
GLN CA  CB   sing N N 94  
GLN CA  HA   sing N N 95  
GLN C   O    doub N N 96  
GLN C   OXT  sing N N 97  
GLN CB  CG   sing N N 98  
GLN CB  HB2  sing N N 99  
GLN CB  HB3  sing N N 100 
GLN CG  CD   sing N N 101 
GLN CG  HG2  sing N N 102 
GLN CG  HG3  sing N N 103 
GLN CD  OE1  doub N N 104 
GLN CD  NE2  sing N N 105 
GLN NE2 HE21 sing N N 106 
GLN NE2 HE22 sing N N 107 
GLN OXT HXT  sing N N 108 
GLU N   CA   sing N N 109 
GLU N   H    sing N N 110 
GLU N   H2   sing N N 111 
GLU CA  C    sing N N 112 
GLU CA  CB   sing N N 113 
GLU CA  HA   sing N N 114 
GLU C   O    doub N N 115 
GLU C   OXT  sing N N 116 
GLU CB  CG   sing N N 117 
GLU CB  HB2  sing N N 118 
GLU CB  HB3  sing N N 119 
GLU CG  CD   sing N N 120 
GLU CG  HG2  sing N N 121 
GLU CG  HG3  sing N N 122 
GLU CD  OE1  doub N N 123 
GLU CD  OE2  sing N N 124 
GLU OE2 HE2  sing N N 125 
GLU OXT HXT  sing N N 126 
GLY N   CA   sing N N 127 
GLY N   H    sing N N 128 
GLY N   H2   sing N N 129 
GLY CA  C    sing N N 130 
GLY CA  HA2  sing N N 131 
GLY CA  HA3  sing N N 132 
GLY C   O    doub N N 133 
GLY C   OXT  sing N N 134 
GLY OXT HXT  sing N N 135 
HIS N   CA   sing N N 136 
HIS N   H    sing N N 137 
HIS N   H2   sing N N 138 
HIS CA  C    sing N N 139 
HIS CA  CB   sing N N 140 
HIS CA  HA   sing N N 141 
HIS C   O    doub N N 142 
HIS C   OXT  sing N N 143 
HIS CB  CG   sing N N 144 
HIS CB  HB2  sing N N 145 
HIS CB  HB3  sing N N 146 
HIS CG  ND1  sing Y N 147 
HIS CG  CD2  doub Y N 148 
HIS ND1 CE1  doub Y N 149 
HIS ND1 HD1  sing N N 150 
HIS CD2 NE2  sing Y N 151 
HIS CD2 HD2  sing N N 152 
HIS CE1 NE2  sing Y N 153 
HIS CE1 HE1  sing N N 154 
HIS NE2 HE2  sing N N 155 
HIS OXT HXT  sing N N 156 
HOH O   H1   sing N N 157 
HOH O   H2   sing N N 158 
ILE N   CA   sing N N 159 
ILE N   H    sing N N 160 
ILE N   H2   sing N N 161 
ILE CA  C    sing N N 162 
ILE CA  CB   sing N N 163 
ILE CA  HA   sing N N 164 
ILE C   O    doub N N 165 
ILE C   OXT  sing N N 166 
ILE CB  CG1  sing N N 167 
ILE CB  CG2  sing N N 168 
ILE CB  HB   sing N N 169 
ILE CG1 CD1  sing N N 170 
ILE CG1 HG12 sing N N 171 
ILE CG1 HG13 sing N N 172 
ILE CG2 HG21 sing N N 173 
ILE CG2 HG22 sing N N 174 
ILE CG2 HG23 sing N N 175 
ILE CD1 HD11 sing N N 176 
ILE CD1 HD12 sing N N 177 
ILE CD1 HD13 sing N N 178 
ILE OXT HXT  sing N N 179 
IMD N1  C2   sing Y N 180 
IMD N1  C5   sing Y N 181 
IMD N1  HN1  sing N N 182 
IMD C2  N3   doub Y N 183 
IMD C2  H2   sing N N 184 
IMD N3  C4   sing Y N 185 
IMD N3  HN3  sing N N 186 
IMD C4  C5   doub Y N 187 
IMD C4  H4   sing N N 188 
IMD C5  H5   sing N N 189 
LEU N   CA   sing N N 190 
LEU N   H    sing N N 191 
LEU N   H2   sing N N 192 
LEU CA  C    sing N N 193 
LEU CA  CB   sing N N 194 
LEU CA  HA   sing N N 195 
LEU C   O    doub N N 196 
LEU C   OXT  sing N N 197 
LEU CB  CG   sing N N 198 
LEU CB  HB2  sing N N 199 
LEU CB  HB3  sing N N 200 
LEU CG  CD1  sing N N 201 
LEU CG  CD2  sing N N 202 
LEU CG  HG   sing N N 203 
LEU CD1 HD11 sing N N 204 
LEU CD1 HD12 sing N N 205 
LEU CD1 HD13 sing N N 206 
LEU CD2 HD21 sing N N 207 
LEU CD2 HD22 sing N N 208 
LEU CD2 HD23 sing N N 209 
LEU OXT HXT  sing N N 210 
LYS N   CA   sing N N 211 
LYS N   H    sing N N 212 
LYS N   H2   sing N N 213 
LYS CA  C    sing N N 214 
LYS CA  CB   sing N N 215 
LYS CA  HA   sing N N 216 
LYS C   O    doub N N 217 
LYS C   OXT  sing N N 218 
LYS CB  CG   sing N N 219 
LYS CB  HB2  sing N N 220 
LYS CB  HB3  sing N N 221 
LYS CG  CD   sing N N 222 
LYS CG  HG2  sing N N 223 
LYS CG  HG3  sing N N 224 
LYS CD  CE   sing N N 225 
LYS CD  HD2  sing N N 226 
LYS CD  HD3  sing N N 227 
LYS CE  NZ   sing N N 228 
LYS CE  HE2  sing N N 229 
LYS CE  HE3  sing N N 230 
LYS NZ  HZ1  sing N N 231 
LYS NZ  HZ2  sing N N 232 
LYS NZ  HZ3  sing N N 233 
LYS OXT HXT  sing N N 234 
MET N   CA   sing N N 235 
MET N   H    sing N N 236 
MET N   H2   sing N N 237 
MET CA  C    sing N N 238 
MET CA  CB   sing N N 239 
MET CA  HA   sing N N 240 
MET C   O    doub N N 241 
MET C   OXT  sing N N 242 
MET CB  CG   sing N N 243 
MET CB  HB2  sing N N 244 
MET CB  HB3  sing N N 245 
MET CG  SD   sing N N 246 
MET CG  HG2  sing N N 247 
MET CG  HG3  sing N N 248 
MET SD  CE   sing N N 249 
MET CE  HE1  sing N N 250 
MET CE  HE2  sing N N 251 
MET CE  HE3  sing N N 252 
MET OXT HXT  sing N N 253 
NAP PA  O1A  doub N N 254 
NAP PA  O2A  sing N N 255 
NAP PA  O5B  sing N N 256 
NAP PA  O3   sing N N 257 
NAP O2A HOA2 sing N N 258 
NAP O5B C5B  sing N N 259 
NAP C5B C4B  sing N N 260 
NAP C5B H51A sing N N 261 
NAP C5B H52A sing N N 262 
NAP C4B O4B  sing N N 263 
NAP C4B C3B  sing N N 264 
NAP C4B H4B  sing N N 265 
NAP O4B C1B  sing N N 266 
NAP C3B O3B  sing N N 267 
NAP C3B C2B  sing N N 268 
NAP C3B H3B  sing N N 269 
NAP O3B HO3A sing N N 270 
NAP C2B O2B  sing N N 271 
NAP C2B C1B  sing N N 272 
NAP C2B H2B  sing N N 273 
NAP O2B P2B  sing N N 274 
NAP C1B N9A  sing N N 275 
NAP C1B H1B  sing N N 276 
NAP N9A C8A  sing Y N 277 
NAP N9A C4A  sing Y N 278 
NAP C8A N7A  doub Y N 279 
NAP C8A H8A  sing N N 280 
NAP N7A C5A  sing Y N 281 
NAP C5A C6A  sing Y N 282 
NAP C5A C4A  doub Y N 283 
NAP C6A N6A  sing N N 284 
NAP C6A N1A  doub Y N 285 
NAP N6A H61A sing N N 286 
NAP N6A H62A sing N N 287 
NAP N1A C2A  sing Y N 288 
NAP C2A N3A  doub Y N 289 
NAP C2A H2A  sing N N 290 
NAP N3A C4A  sing Y N 291 
NAP O3  PN   sing N N 292 
NAP PN  O1N  doub N N 293 
NAP PN  O2N  sing N N 294 
NAP PN  O5D  sing N N 295 
NAP O5D C5D  sing N N 296 
NAP C5D C4D  sing N N 297 
NAP C5D H51N sing N N 298 
NAP C5D H52N sing N N 299 
NAP C4D O4D  sing N N 300 
NAP C4D C3D  sing N N 301 
NAP C4D H4D  sing N N 302 
NAP O4D C1D  sing N N 303 
NAP C3D O3D  sing N N 304 
NAP C3D C2D  sing N N 305 
NAP C3D H3D  sing N N 306 
NAP O3D HO3N sing N N 307 
NAP C2D O2D  sing N N 308 
NAP C2D C1D  sing N N 309 
NAP C2D H2D  sing N N 310 
NAP O2D HO2N sing N N 311 
NAP C1D N1N  sing N N 312 
NAP C1D H1D  sing N N 313 
NAP N1N C2N  sing Y N 314 
NAP N1N C6N  doub Y N 315 
NAP C2N C3N  doub Y N 316 
NAP C2N H2N  sing N N 317 
NAP C3N C7N  sing N N 318 
NAP C3N C4N  sing Y N 319 
NAP C7N O7N  doub N N 320 
NAP C7N N7N  sing N N 321 
NAP N7N H71N sing N N 322 
NAP N7N H72N sing N N 323 
NAP C4N C5N  doub Y N 324 
NAP C4N H4N  sing N N 325 
NAP C5N C6N  sing Y N 326 
NAP C5N H5N  sing N N 327 
NAP C6N H6N  sing N N 328 
NAP P2B O1X  doub N N 329 
NAP P2B O2X  sing N N 330 
NAP P2B O3X  sing N N 331 
NAP O2X HOP2 sing N N 332 
NAP O3X HOP3 sing N N 333 
OXM C1  N1   sing N N 334 
OXM C1  O1   doub N N 335 
OXM C1  C2   sing N N 336 
OXM N1  HN1  sing N N 337 
OXM N1  HN2  sing N N 338 
OXM C2  O2   doub N N 339 
OXM C2  O3   sing N N 340 
OXM O3  HO3  sing N N 341 
PHE N   CA   sing N N 342 
PHE N   H    sing N N 343 
PHE N   H2   sing N N 344 
PHE CA  C    sing N N 345 
PHE CA  CB   sing N N 346 
PHE CA  HA   sing N N 347 
PHE C   O    doub N N 348 
PHE C   OXT  sing N N 349 
PHE CB  CG   sing N N 350 
PHE CB  HB2  sing N N 351 
PHE CB  HB3  sing N N 352 
PHE CG  CD1  doub Y N 353 
PHE CG  CD2  sing Y N 354 
PHE CD1 CE1  sing Y N 355 
PHE CD1 HD1  sing N N 356 
PHE CD2 CE2  doub Y N 357 
PHE CD2 HD2  sing N N 358 
PHE CE1 CZ   doub Y N 359 
PHE CE1 HE1  sing N N 360 
PHE CE2 CZ   sing Y N 361 
PHE CE2 HE2  sing N N 362 
PHE CZ  HZ   sing N N 363 
PHE OXT HXT  sing N N 364 
PRO N   CA   sing N N 365 
PRO N   CD   sing N N 366 
PRO N   H    sing N N 367 
PRO CA  C    sing N N 368 
PRO CA  CB   sing N N 369 
PRO CA  HA   sing N N 370 
PRO C   O    doub N N 371 
PRO C   OXT  sing N N 372 
PRO CB  CG   sing N N 373 
PRO CB  HB2  sing N N 374 
PRO CB  HB3  sing N N 375 
PRO CG  CD   sing N N 376 
PRO CG  HG2  sing N N 377 
PRO CG  HG3  sing N N 378 
PRO CD  HD2  sing N N 379 
PRO CD  HD3  sing N N 380 
PRO OXT HXT  sing N N 381 
SER N   CA   sing N N 382 
SER N   H    sing N N 383 
SER N   H2   sing N N 384 
SER CA  C    sing N N 385 
SER CA  CB   sing N N 386 
SER CA  HA   sing N N 387 
SER C   O    doub N N 388 
SER C   OXT  sing N N 389 
SER CB  OG   sing N N 390 
SER CB  HB2  sing N N 391 
SER CB  HB3  sing N N 392 
SER OG  HG   sing N N 393 
SER OXT HXT  sing N N 394 
THR N   CA   sing N N 395 
THR N   H    sing N N 396 
THR N   H2   sing N N 397 
THR CA  C    sing N N 398 
THR CA  CB   sing N N 399 
THR CA  HA   sing N N 400 
THR C   O    doub N N 401 
THR C   OXT  sing N N 402 
THR CB  OG1  sing N N 403 
THR CB  CG2  sing N N 404 
THR CB  HB   sing N N 405 
THR OG1 HG1  sing N N 406 
THR CG2 HG21 sing N N 407 
THR CG2 HG22 sing N N 408 
THR CG2 HG23 sing N N 409 
THR OXT HXT  sing N N 410 
TRP N   CA   sing N N 411 
TRP N   H    sing N N 412 
TRP N   H2   sing N N 413 
TRP CA  C    sing N N 414 
TRP CA  CB   sing N N 415 
TRP CA  HA   sing N N 416 
TRP C   O    doub N N 417 
TRP C   OXT  sing N N 418 
TRP CB  CG   sing N N 419 
TRP CB  HB2  sing N N 420 
TRP CB  HB3  sing N N 421 
TRP CG  CD1  doub Y N 422 
TRP CG  CD2  sing Y N 423 
TRP CD1 NE1  sing Y N 424 
TRP CD1 HD1  sing N N 425 
TRP CD2 CE2  doub Y N 426 
TRP CD2 CE3  sing Y N 427 
TRP NE1 CE2  sing Y N 428 
TRP NE1 HE1  sing N N 429 
TRP CE2 CZ2  sing Y N 430 
TRP CE3 CZ3  doub Y N 431 
TRP CE3 HE3  sing N N 432 
TRP CZ2 CH2  doub Y N 433 
TRP CZ2 HZ2  sing N N 434 
TRP CZ3 CH2  sing Y N 435 
TRP CZ3 HZ3  sing N N 436 
TRP CH2 HH2  sing N N 437 
TRP OXT HXT  sing N N 438 
TYR N   CA   sing N N 439 
TYR N   H    sing N N 440 
TYR N   H2   sing N N 441 
TYR CA  C    sing N N 442 
TYR CA  CB   sing N N 443 
TYR CA  HA   sing N N 444 
TYR C   O    doub N N 445 
TYR C   OXT  sing N N 446 
TYR CB  CG   sing N N 447 
TYR CB  HB2  sing N N 448 
TYR CB  HB3  sing N N 449 
TYR CG  CD1  doub Y N 450 
TYR CG  CD2  sing Y N 451 
TYR CD1 CE1  sing Y N 452 
TYR CD1 HD1  sing N N 453 
TYR CD2 CE2  doub Y N 454 
TYR CD2 HD2  sing N N 455 
TYR CE1 CZ   doub Y N 456 
TYR CE1 HE1  sing N N 457 
TYR CE2 CZ   sing Y N 458 
TYR CE2 HE2  sing N N 459 
TYR CZ  OH   sing N N 460 
TYR OH  HH   sing N N 461 
TYR OXT HXT  sing N N 462 
VAL N   CA   sing N N 463 
VAL N   H    sing N N 464 
VAL N   H2   sing N N 465 
VAL CA  C    sing N N 466 
VAL CA  CB   sing N N 467 
VAL CA  HA   sing N N 468 
VAL C   O    doub N N 469 
VAL C   OXT  sing N N 470 
VAL CB  CG1  sing N N 471 
VAL CB  CG2  sing N N 472 
VAL CB  HB   sing N N 473 
VAL CG1 HG11 sing N N 474 
VAL CG1 HG12 sing N N 475 
VAL CG1 HG13 sing N N 476 
VAL CG2 HG21 sing N N 477 
VAL CG2 HG22 sing N N 478 
VAL CG2 HG23 sing N N 479 
VAL OXT HXT  sing N N 480 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   8ZMX 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.crystal_system   tetragonal 
_space_group.IT_number        96 
_space_group.name_H-M_alt     'P 43 21 2' 
_space_group.name_Hall        'P 4nw 2abw' 
_space_group.id               1 
# 
_atom_sites.entry_id                    9KSN 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.006407 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.006407 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.008904 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 7.96527 ?       ? ? 9.05267  ?        ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
P ? ? 9.51135 5.44231 ? ? 1.42069  35.72801 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . ARG A 1 45  ? 2.42069   1.03741   22.54753  1.000 83.28213  ? 5   ARG A N   1 
ATOM   2    C CA  . ARG A 1 45  ? 1.38761   0.83906   23.55801  1.000 96.29655  ? 5   ARG A CA  1 
ATOM   3    C C   . ARG A 1 45  ? 1.96085   0.00897   24.70126  1.000 96.75096  ? 5   ARG A C   1 
ATOM   4    O O   . ARG A 1 45  ? 1.58327   0.17376   25.86327  1.000 95.15719  ? 5   ARG A O   1 
ATOM   5    C CB  . ARG A 1 45  ? 0.15754   0.17960   22.93570  1.000 97.91611  ? 5   ARG A CB  1 
ATOM   6    C CG  . ARG A 1 45  ? -1.03884  0.08763   23.85705  1.000 104.55482 ? 5   ARG A CG  1 
ATOM   7    C CD  . ARG A 1 45  ? -2.31411  0.07519   23.04247  1.000 98.88906  ? 5   ARG A CD  1 
ATOM   8    N NE  . ARG A 1 45  ? -2.46396  1.35961   22.36874  1.000 120.54132 ? 5   ARG A NE  1 
ATOM   9    C CZ  . ARG A 1 45  ? -3.09011  2.40543   22.88994  1.000 107.48222 ? 5   ARG A CZ  1 
ATOM   10   N NH1 . ARG A 1 45  ? -3.65499  2.34631   24.08453  1.000 100.09299 ? 5   ARG A NH1 1 
ATOM   11   N NH2 . ARG A 1 45  ? -3.13518  3.54405   22.20393  1.000 103.26028 ? 5   ARG A NH2 1 
ATOM   12   N N   . THR A 1 46  ? 2.86335   -0.89687  24.34490  1.000 90.84632  ? 6   THR A N   1 
ATOM   13   C CA  . THR A 1 46  ? 3.66820   -1.63344  25.30235  1.000 71.82494  ? 6   THR A CA  1 
ATOM   14   C C   . THR A 1 46  ? 4.90385   -0.80852  25.63735  1.000 74.18745  ? 6   THR A C   1 
ATOM   15   O O   . THR A 1 46  ? 5.26342   0.13194   24.92189  1.000 78.73280  ? 6   THR A O   1 
ATOM   16   C CB  . THR A 1 46  ? 4.08439   -3.00120  24.75716  1.000 77.59307  ? 6   THR A CB  1 
ATOM   17   O OG1 . THR A 1 46  ? 4.68001   -2.84946  23.46232  1.000 84.58217  ? 6   THR A OG1 1 
ATOM   18   C CG2 . THR A 1 46  ? 2.88280   -3.92534  24.65779  1.000 82.40342  ? 6   THR A CG2 1 
ATOM   19   N N   . GLU A 1 47  ? 5.53376   -1.14382  26.76091  1.000 76.91171  ? 7   GLU A N   1 
ATOM   20   C CA  . GLU A 1 47  ? 6.70537   -0.39341  27.18990  1.000 72.61076  ? 7   GLU A CA  1 
ATOM   21   C C   . GLU A 1 47  ? 7.79542   -0.54034  26.13783  1.000 80.23529  ? 7   GLU A C   1 
ATOM   22   O O   . GLU A 1 47  ? 8.00089   0.36473   25.32282  1.000 84.16938  ? 7   GLU A O   1 
ATOM   23   C CB  . GLU A 1 47  ? 7.20712   -0.88697  28.54335  1.000 71.58384  ? 7   GLU A CB  1 
ATOM   24   C CG  . GLU A 1 47  ? 8.05604   0.12416   29.28748  1.000 69.75297  ? 7   GLU A CG  1 
ATOM   25   C CD  . GLU A 1 47  ? 8.63260   -0.43660  30.57012  1.000 71.34584  ? 7   GLU A CD  1 
ATOM   26   O OE1 . GLU A 1 47  ? 8.34647   -1.60824  30.89565  1.000 82.96772  ? 7   GLU A OE1 1 
ATOM   27   O OE2 . GLU A 1 47  ? 9.39627   0.28500   31.24472  1.000 69.25293  ? 7   GLU A OE2 1 
ATOM   28   N N   . ARG A 1 48  ? 8.51985   -1.65953  26.16930  1.000 78.42871  ? 8   ARG A N   1 
ATOM   29   C CA  . ARG A 1 48  ? 9.57766   -1.90940  25.20236  1.000 70.05886  ? 8   ARG A CA  1 
ATOM   30   C C   . ARG A 1 48  ? 8.97585   -2.66876  24.02441  1.000 68.99053  ? 8   ARG A C   1 
ATOM   31   O O   . ARG A 1 48  ? 8.63912   -3.85288  24.17612  1.000 78.01980  ? 8   ARG A O   1 
ATOM   32   C CB  . ARG A 1 48  ? 10.70510  -2.70762  25.84084  1.000 81.51687  ? 8   ARG A CB  1 
ATOM   33   C CG  . ARG A 1 48  ? 11.24900  -2.06685  27.10582  1.000 75.12606  ? 8   ARG A CG  1 
ATOM   34   C CD  . ARG A 1 48  ? 11.98894  -0.78683  26.76999  1.000 81.24473  ? 8   ARG A CD  1 
ATOM   35   N NE  . ARG A 1 48  ? 12.13972  0.09921   27.91868  1.000 90.52919  ? 8   ARG A NE  1 
ATOM   36   C CZ  . ARG A 1 48  ? 13.25162  0.23320   28.62903  1.000 85.91046  ? 8   ARG A CZ  1 
ATOM   37   N NH1 . ARG A 1 48  ? 14.34089  -0.46211  28.34655  1.000 68.55728  ? 8   ARG A NH1 1 
ATOM   38   N NH2 . ARG A 1 48  ? 13.27189  1.09054   29.64636  1.000 58.92720  ? 8   ARG A NH2 1 
ATOM   39   N N   . PRO A 1 49  ? 8.80299   -2.04515  22.86217  1.000 70.17835  ? 9   PRO A N   1 
ATOM   40   C CA  . PRO A 1 49  ? 8.19739   -2.75009  21.72705  1.000 63.74206  ? 9   PRO A CA  1 
ATOM   41   C C   . PRO A 1 49  ? 9.11293   -3.84600  21.20830  1.000 56.88263  ? 9   PRO A C   1 
ATOM   42   O O   . PRO A 1 49  ? 10.33656  -3.78092  21.34744  1.000 57.55455  ? 9   PRO A O   1 
ATOM   43   C CB  . PRO A 1 49  ? 8.00679   -1.64449  20.68036  1.000 54.29422  ? 9   PRO A CB  1 
ATOM   44   C CG  . PRO A 1 49  ? 8.12257   -0.36008  21.44042  1.000 63.03381  ? 9   PRO A CG  1 
ATOM   45   C CD  . PRO A 1 49  ? 9.07647   -0.63602  22.55035  1.000 61.29343  ? 9   PRO A CD  1 
ATOM   46   N N   . ILE A 1 50  ? 8.50438   -4.86860  20.60725  1.000 62.86335  ? 10  ILE A N   1 
ATOM   47   C CA  . ILE A 1 50  ? 9.28216   -5.92423  19.96853  1.000 58.56752  ? 10  ILE A CA  1 
ATOM   48   C C   . ILE A 1 50  ? 9.84999   -5.39964  18.65689  1.000 60.70711  ? 10  ILE A C   1 
ATOM   49   O O   . ILE A 1 50  ? 9.11684   -4.86983  17.81092  1.000 62.57538  ? 10  ILE A O   1 
ATOM   50   C CB  . ILE A 1 50  ? 8.42244   -7.17689  19.74435  1.000 53.65427  ? 10  ILE A CB  1 
ATOM   51   C CG1 . ILE A 1 50  ? 7.68836   -7.55125  21.03399  1.000 61.62976  ? 10  ILE A CG1 1 
ATOM   52   C CG2 . ILE A 1 50  ? 9.28833   -8.33445  19.26044  1.000 54.93077  ? 10  ILE A CG2 1 
ATOM   53   C CD1 . ILE A 1 50  ? 6.60827   -8.59182  20.85060  1.000 61.33287  ? 10  ILE A CD1 1 
ATOM   54   N N   . ARG A 1 51  ? 11.16035  -5.54311  18.47945  1.000 52.70067  ? 11  ARG A N   1 
ATOM   55   C CA  . ARG A 1 51  ? 11.82713  -5.08556  17.26656  1.000 53.43185  ? 11  ARG A CA  1 
ATOM   56   C C   . ARG A 1 51  ? 11.90362  -6.23902  16.27338  1.000 51.42841  ? 11  ARG A C   1 
ATOM   57   O O   . ARG A 1 51  ? 12.56448  -7.24989  16.53640  1.000 53.32171  ? 11  ARG A O   1 
ATOM   58   C CB  . ARG A 1 51  ? 13.21845  -4.54018  17.58392  1.000 55.47638  ? 11  ARG A CB  1 
ATOM   59   C CG  . ARG A 1 51  ? 13.20545  -3.39535  18.58898  1.000 62.32112  ? 11  ARG A CG  1 
ATOM   60   C CD  . ARG A 1 51  ? 14.43020  -2.49835  18.46393  1.000 57.56535  ? 11  ARG A CD  1 
ATOM   61   N NE  . ARG A 1 51  ? 14.27782  -1.50720  17.40445  1.000 67.57279  ? 11  ARG A NE  1 
ATOM   62   C CZ  . ARG A 1 51  ? 15.05830  -1.41829  16.33609  1.000 60.57582  ? 11  ARG A CZ  1 
ATOM   63   N NH1 . ARG A 1 51  ? 16.07373  -2.24505  16.15111  1.000 60.01677  ? 11  ARG A NH1 1 
ATOM   64   N NH2 . ARG A 1 51  ? 14.81722  -0.47142  15.43319  1.000 72.53906  ? 11  ARG A NH2 1 
ATOM   65   N N   . VAL A 1 52  ? 11.22997  -6.08540  15.13691  1.000 40.23379  ? 12  VAL A N   1 
ATOM   66   C CA  . VAL A 1 52  ? 11.07486  -7.14655  14.14926  1.000 50.53175  ? 12  VAL A CA  1 
ATOM   67   C C   . VAL A 1 52  ? 11.81998  -6.75297  12.88225  1.000 44.09243  ? 12  VAL A C   1 
ATOM   68   O O   . VAL A 1 52  ? 11.66192  -5.63159  12.38425  1.000 50.26640  ? 12  VAL A O   1 
ATOM   69   C CB  . VAL A 1 52  ? 9.58960   -7.41197  13.84831  1.000 51.05404  ? 12  VAL A CB  1 
ATOM   70   C CG1 . VAL A 1 52  ? 9.44784   -8.42995  12.72939  1.000 42.43064  ? 12  VAL A CG1 1 
ATOM   71   C CG2 . VAL A 1 52  ? 8.86238   -7.87623  15.10583  1.000 42.20781  ? 12  VAL A CG2 1 
ATOM   72   N N   . ALA A 1 53  ? 12.61922  -7.67746  12.35650  1.000 48.56963  ? 13  ALA A N   1 
ATOM   73   C CA  . ALA A 1 53  ? 13.27806  -7.51460  11.06925  1.000 52.16345  ? 13  ALA A CA  1 
ATOM   74   C C   . ALA A 1 53  ? 12.65505  -8.44935  10.04099  1.000 52.61323  ? 13  ALA A C   1 
ATOM   75   O O   . ALA A 1 53  ? 12.33174  -9.60032  10.35087  1.000 51.81126  ? 13  ALA A O   1 
ATOM   76   C CB  . ALA A 1 53  ? 14.77869  -7.79051  11.18068  1.000 46.31475  ? 13  ALA A CB  1 
ATOM   77   N N   . ILE A 1 54  ? 12.48620  -7.95047  8.81937   1.000 47.79024  ? 14  ILE A N   1 
ATOM   78   C CA  . ILE A 1 54  ? 11.93762  -8.72982  7.71341   1.000 45.79868  ? 14  ILE A CA  1 
ATOM   79   C C   . ILE A 1 54  ? 13.08667  -9.14521  6.80209   1.000 54.35995  ? 14  ILE A C   1 
ATOM   80   O O   . ILE A 1 54  ? 13.79474  -8.29054  6.25524   1.000 49.19621  ? 14  ILE A O   1 
ATOM   81   C CB  . ILE A 1 54  ? 10.87530  -7.93460  6.93803   1.000 46.34824  ? 14  ILE A CB  1 
ATOM   82   C CG1 . ILE A 1 54  ? 9.67966   -7.62206  7.83928   1.000 41.84824  ? 14  ILE A CG1 1 
ATOM   83   C CG2 . ILE A 1 54  ? 10.42020  -8.70589  5.70679   1.000 46.42817  ? 14  ILE A CG2 1 
ATOM   84   C CD1 . ILE A 1 54  ? 8.69391   -6.66479  7.21923   1.000 54.83595  ? 14  ILE A CD1 1 
ATOM   85   N N   . ILE A 1 55  ? 13.26956  -10.45207 6.63090   1.000 45.92079  ? 15  ILE A N   1 
ATOM   86   C CA  . ILE A 1 55  ? 14.35652  -11.00422 5.82851   1.000 46.30151  ? 15  ILE A CA  1 
ATOM   87   C C   . ILE A 1 55  ? 13.78379  -11.40418 4.47333   1.000 53.76904  ? 15  ILE A C   1 
ATOM   88   O O   . ILE A 1 55  ? 13.02764  -12.37630 4.36721   1.000 49.50173  ? 15  ILE A O   1 
ATOM   89   C CB  . ILE A 1 55  ? 15.02679  -12.19593 6.52445   1.000 50.90668  ? 15  ILE A CB  1 
ATOM   90   C CG1 . ILE A 1 55  ? 15.25139  -11.89671 8.00800   1.000 46.58117  ? 15  ILE A CG1 1 
ATOM   91   C CG2 . ILE A 1 55  ? 16.33971  -12.53832 5.83951   1.000 44.57666  ? 15  ILE A CG2 1 
ATOM   92   C CD1 . ILE A 1 55  ? 16.14753  -10.71295 8.25974   1.000 41.55973  ? 15  ILE A CD1 1 
ATOM   93   N N   . GLY A 1 56  ? 14.14423  -10.65835 3.43144   1.000 51.06866  ? 16  GLY A N   1 
ATOM   94   C CA  . GLY A 1 56  ? 13.66242  -10.93669 2.09134   1.000 66.06360  ? 16  GLY A CA  1 
ATOM   95   C C   . GLY A 1 56  ? 12.37683  -10.19581 1.78507   1.000 59.36793  ? 16  GLY A C   1 
ATOM   96   O O   . GLY A 1 56  ? 11.36259  -10.41056 2.45576   1.000 61.67769  ? 16  GLY A O   1 
ATOM   97   N N   . TYR A 1 57  ? 12.39829  -9.32374  0.78164   1.000 60.78800  ? 17  TYR A N   1 
ATOM   98   C CA  . TYR A 1 57  ? 11.26160  -8.46317  0.47356   1.000 59.02277  ? 17  TYR A CA  1 
ATOM   99   C C   . TYR A 1 57  ? 10.60076  -8.93577  -0.81847  1.000 62.07901  ? 17  TYR A C   1 
ATOM   100  O O   . TYR A 1 57  ? 10.69635  -8.30623  -1.87670  1.000 70.45478  ? 17  TYR A O   1 
ATOM   101  C CB  . TYR A 1 57  ? 11.71031  -7.00573  0.38309   1.000 62.04973  ? 17  TYR A CB  1 
ATOM   102  C CG  . TYR A 1 57  ? 10.58221  -6.01545  0.55983   1.000 63.30696  ? 17  TYR A CG  1 
ATOM   103  C CD1 . TYR A 1 57  ? 9.93692   -5.88338  1.78320   1.000 55.24660  ? 17  TYR A CD1 1 
ATOM   104  C CD2 . TYR A 1 57  ? 10.16209  -5.21207  -0.49225  1.000 62.16360  ? 17  TYR A CD2 1 
ATOM   105  C CE1 . TYR A 1 57  ? 8.90568   -4.98043  1.95440   1.000 63.15912  ? 17  TYR A CE1 1 
ATOM   106  C CE2 . TYR A 1 57  ? 9.13107   -4.30338  -0.32930  1.000 54.38582  ? 17  TYR A CE2 1 
ATOM   107  C CZ  . TYR A 1 57  ? 8.50725   -4.19372  0.89627   1.000 64.28605  ? 17  TYR A CZ  1 
ATOM   108  O OH  . TYR A 1 57  ? 7.48027   -3.29536  1.06799   1.000 65.46808  ? 17  TYR A OH  1 
ATOM   109  N N   . GLY A 1 58  ? 9.91862   -10.06620 -0.71089  1.000 68.25567  ? 18  GLY A N   1 
ATOM   110  C CA  . GLY A 1 58  ? 9.06135   -10.61713 -1.73335  1.000 61.29345  ? 18  GLY A CA  1 
ATOM   111  C C   . GLY A 1 58  ? 7.60282   -10.34680 -1.43814  1.000 63.91437  ? 18  GLY A C   1 
ATOM   112  O O   . GLY A 1 58  ? 7.24572   -9.32365  -0.84394  1.000 72.42556  ? 18  GLY A O   1 
ATOM   113  N N   . ASN A 1 59  ? 6.74518   -11.28425 -1.84619  1.000 60.97385  ? 19  ASN A N   1 
ATOM   114  C CA  . ASN A 1 59  ? 5.31941   -11.16227 -1.55627  1.000 63.62350  ? 19  ASN A CA  1 
ATOM   115  C C   . ASN A 1 59  ? 5.05362   -11.19343 -0.05593  1.000 58.87875  ? 19  ASN A C   1 
ATOM   116  O O   . ASN A 1 59  ? 4.34751   -10.33082 0.48069   1.000 61.76205  ? 19  ASN A O   1 
ATOM   117  C CB  . ASN A 1 59  ? 4.55119   -12.28779 -2.25239  1.000 66.64387  ? 19  ASN A CB  1 
ATOM   118  C CG  . ASN A 1 59  ? 4.29097   -12.00158 -3.71443  1.000 73.45401  ? 19  ASN A CG  1 
ATOM   119  O OD1 . ASN A 1 59  ? 3.86797   -10.90425 -4.07497  1.000 68.94857  ? 19  ASN A OD1 1 
ATOM   120  N ND2 . ASN A 1 59  ? 4.53992   -12.98874 -4.56641  1.000 79.44005  ? 19  ASN A ND2 1 
ATOM   121  N N   . ILE A 1 60  ? 5.61224   -12.18762 0.63870   1.000 54.25594  ? 20  ILE A N   1 
ATOM   122  C CA  . ILE A 1 60  ? 5.39932   -12.29944 2.07955   1.000 52.72732  ? 20  ILE A CA  1 
ATOM   123  C C   . ILE A 1 60  ? 5.97838   -11.09233 2.80626   1.000 58.50384  ? 20  ILE A C   1 
ATOM   124  O O   . ILE A 1 60  ? 5.36049   -10.55424 3.73221   1.000 56.52844  ? 20  ILE A O   1 
ATOM   125  C CB  . ILE A 1 60  ? 5.98687   -13.62057 2.61010   1.000 58.86630  ? 20  ILE A CB  1 
ATOM   126  C CG1 . ILE A 1 60  ? 5.28577   -14.81250 1.95776   1.000 63.39347  ? 20  ILE A CG1 1 
ATOM   127  C CG2 . ILE A 1 60  ? 5.83691   -13.70600 4.12318   1.000 55.92493  ? 20  ILE A CG2 1 
ATOM   128  C CD1 . ILE A 1 60  ? 3.81742   -14.92172 2.30468   1.000 57.77531  ? 20  ILE A CD1 1 
ATOM   129  N N   . GLY A 1 61  ? 7.16595   -10.64241 2.39480   1.000 54.29257  ? 21  GLY A N   1 
ATOM   130  C CA  . GLY A 1 61  ? 7.80145   -9.52521  3.07657   1.000 51.08574  ? 21  GLY A CA  1 
ATOM   131  C C   . GLY A 1 61  ? 7.01791   -8.23077  2.96649   1.000 54.18615  ? 21  GLY A C   1 
ATOM   132  O O   . GLY A 1 61  ? 6.97036   -7.44133  3.91323   1.000 49.47776  ? 21  GLY A O   1 
ATOM   133  N N   . GLN A 1 62  ? 6.40680   -7.98658  1.80482   1.000 55.31335  ? 22  GLN A N   1 
ATOM   134  C CA  . GLN A 1 62  ? 5.62386   -6.76763  1.62175   1.000 50.91973  ? 22  GLN A CA  1 
ATOM   135  C C   . GLN A 1 62  ? 4.41901   -6.73383  2.55272   1.000 57.84859  ? 22  GLN A C   1 
ATOM   136  O O   . GLN A 1 62  ? 4.11862   -5.69551  3.15399   1.000 61.67128  ? 22  GLN A O   1 
ATOM   137  C CB  . GLN A 1 62  ? 5.17998   -6.64821  0.16422   1.000 53.35568  ? 22  GLN A CB  1 
ATOM   138  C CG  . GLN A 1 62  ? 6.32778   -6.41658  -0.80920  1.000 64.12798  ? 22  GLN A CG  1 
ATOM   139  C CD  . GLN A 1 62  ? 5.97084   -6.78220  -2.23668  1.000 74.60012  ? 22  GLN A CD  1 
ATOM   140  O OE1 . GLN A 1 62  ? 4.79774   -6.93518  -2.57824  1.000 78.09490  ? 22  GLN A OE1 1 
ATOM   141  N NE2 . GLN A 1 62  ? 6.98675   -6.94092  -3.07576  1.000 72.16498  ? 22  GLN A NE2 1 
ATOM   142  N N   . TYR A 1 63  ? 3.70991   -7.85789  2.67807   1.000 52.45502  ? 23  TYR A N   1 
ATOM   143  C CA  . TYR A 1 63  ? 2.55926   -7.90575  3.57397   1.000 46.04671  ? 23  TYR A CA  1 
ATOM   144  C C   . TYR A 1 63  ? 2.99797   -7.94764  5.03194   1.000 48.50697  ? 23  TYR A C   1 
ATOM   145  O O   . TYR A 1 63  ? 2.32978   -7.37685  5.90273   1.000 44.92058  ? 23  TYR A O   1 
ATOM   146  C CB  . TYR A 1 63  ? 1.68048   -9.10614  3.23414   1.000 51.74643  ? 23  TYR A CB  1 
ATOM   147  C CG  . TYR A 1 63  ? 0.87928   -8.93366  1.96378   1.000 51.21652  ? 23  TYR A CG  1 
ATOM   148  C CD1 . TYR A 1 63  ? 1.37618   -9.36753  0.74322   1.000 49.68454  ? 23  TYR A CD1 1 
ATOM   149  C CD2 . TYR A 1 63  ? -0.37819  -8.34485  1.98568   1.000 47.51572  ? 23  TYR A CD2 1 
ATOM   150  C CE1 . TYR A 1 63  ? 0.64645   -9.21774  -0.42093  1.000 49.55267  ? 23  TYR A CE1 1 
ATOM   151  C CE2 . TYR A 1 63  ? -1.11722  -8.19082  0.82443   1.000 37.64583  ? 23  TYR A CE2 1 
ATOM   152  C CZ  . TYR A 1 63  ? -0.59892  -8.63057  -0.37594  1.000 49.53077  ? 23  TYR A CZ  1 
ATOM   153  O OH  . TYR A 1 63  ? -1.32548  -8.48217  -1.53566  1.000 35.74865  ? 23  TYR A OH  1 
ATOM   154  N N   . ALA A 1 64  ? 4.10922   -8.63436  5.31656   1.000 46.00368  ? 24  ALA A N   1 
ATOM   155  C CA  . ALA A 1 64  ? 4.65447   -8.64807  6.67097   1.000 51.11366  ? 24  ALA A CA  1 
ATOM   156  C C   . ALA A 1 64  ? 4.93926   -7.23483  7.15935   1.000 48.76496  ? 24  ALA A C   1 
ATOM   157  O O   . ALA A 1 64  ? 4.77497   -6.93514  8.34752   1.000 54.52228  ? 24  ALA A O   1 
ATOM   158  C CB  . ALA A 1 64  ? 5.92080   -9.50346  6.72004   1.000 46.32974  ? 24  ALA A CB  1 
ATOM   159  N N   . LEU A 1 65  ? 5.38472   -6.35886  6.25570   1.000 46.73078  ? 25  LEU A N   1 
ATOM   160  C CA  . LEU A 1 65  ? 5.57952   -4.95282  6.59456   1.000 51.27651  ? 25  LEU A CA  1 
ATOM   161  C C   . LEU A 1 65  ? 4.30690   -4.34774  7.17651   1.000 57.30052  ? 25  LEU A C   1 
ATOM   162  O O   . LEU A 1 65  ? 4.33953   -3.66606  8.20741   1.000 58.34957  ? 25  LEU A O   1 
ATOM   163  C CB  . LEU A 1 65  ? 6.01891   -4.18264  5.34633   1.000 59.12789  ? 25  LEU A CB  1 
ATOM   164  C CG  . LEU A 1 65  ? 6.45895   -2.72304  5.47177   1.000 63.90903  ? 25  LEU A CG  1 
ATOM   165  C CD1 . LEU A 1 65  ? 7.95916   -2.63168  5.66087   1.000 67.21311  ? 25  LEU A CD1 1 
ATOM   166  C CD2 . LEU A 1 65  ? 6.02103   -1.92410  4.24767   1.000 72.27767  ? 25  LEU A CD2 1 
ATOM   167  N N   . GLN A 1 66  ? 3.16984   -4.59315  6.52096   1.000 50.55974  ? 26  GLN A N   1 
ATOM   168  C CA  . GLN A 1 66  ? 1.89975   -4.05564  6.99616   1.000 47.58095  ? 26  GLN A CA  1 
ATOM   169  C C   . GLN A 1 66  ? 1.47889   -4.70265  8.30978   1.000 46.97126  ? 26  GLN A C   1 
ATOM   170  O O   . GLN A 1 66  ? 0.93906   -4.02839  9.19438   1.000 50.38558  ? 26  GLN A O   1 
ATOM   171  C CB  . GLN A 1 66  ? 0.82464   -4.25066  5.92778   1.000 49.98565  ? 26  GLN A CB  1 
ATOM   172  C CG  . GLN A 1 66  ? 1.21011   -3.69989  4.56204   1.000 41.51366  ? 26  GLN A CG  1 
ATOM   173  C CD  . GLN A 1 66  ? 0.20839   -4.05412  3.48137   1.000 51.76316  ? 26  GLN A CD  1 
ATOM   174  O OE1 . GLN A 1 66  ? -0.53751  -5.02690  3.60343   1.000 59.68747  ? 26  GLN A OE1 1 
ATOM   175  N NE2 . GLN A 1 66  ? 0.18715   -3.26522  2.41423   1.000 44.50979  ? 26  GLN A NE2 1 
ATOM   176  N N   . ALA A 1 67  ? 1.71084   -6.01019  8.45200   1.000 43.28310  ? 27  ALA A N   1 
ATOM   177  C CA  . ALA A 1 67  ? 1.32649   -6.70457  9.67774   1.000 45.89860  ? 27  ALA A CA  1 
ATOM   178  C C   . ALA A 1 67  ? 2.11070   -6.19032  10.87912  1.000 53.84686  ? 27  ALA A C   1 
ATOM   179  O O   . ALA A 1 67  ? 1.55198   -6.02852  11.97108  1.000 51.24467  ? 27  ALA A O   1 
ATOM   180  C CB  . ALA A 1 67  ? 1.52553   -8.20998  9.51108   1.000 49.97112  ? 27  ALA A CB  1 
ATOM   181  N N   . VAL A 1 68  ? 3.40957   -5.93482  10.69954  1.000 50.11500  ? 28  VAL A N   1 
ATOM   182  C CA  . VAL A 1 68  ? 4.22010   -5.38837  11.78598  1.000 47.00933  ? 28  VAL A CA  1 
ATOM   183  C C   . VAL A 1 68  ? 3.72316   -4.00217  12.17555  1.000 43.11374  ? 28  VAL A C   1 
ATOM   184  O O   . VAL A 1 68  ? 3.63891   -3.66635  13.36365  1.000 52.31357  ? 28  VAL A O   1 
ATOM   185  C CB  . VAL A 1 68  ? 5.70828   -5.36646  11.38804  1.000 46.70904  ? 28  VAL A CB  1 
ATOM   186  C CG1 . VAL A 1 68  ? 6.52354   -4.59228  12.41594  1.000 42.57705  ? 28  VAL A CG1 1 
ATOM   187  C CG2 . VAL A 1 68  ? 6.24507   -6.78489  11.24459  1.000 40.35786  ? 28  VAL A CG2 1 
ATOM   188  N N   . GLU A 1 69  ? 3.39166   -3.17599  11.18133  1.000 45.76520  ? 29  GLU A N   1 
ATOM   189  C CA  . GLU A 1 69  ? 2.92219   -1.82057  11.45167  1.000 43.70097  ? 29  GLU A CA  1 
ATOM   190  C C   . GLU A 1 69  ? 1.65217   -1.83117  12.29697  1.000 50.27669  ? 29  GLU A C   1 
ATOM   191  O O   . GLU A 1 69  ? 1.51526   -1.04558  13.24178  1.000 62.51763  ? 29  GLU A O   1 
ATOM   192  C CB  . GLU A 1 69  ? 2.69218   -1.08674  10.13006  1.000 56.50305  ? 29  GLU A CB  1 
ATOM   193  C CG  . GLU A 1 69  ? 2.27670   0.36773   10.27533  1.000 71.24742  ? 29  GLU A CG  1 
ATOM   194  C CD  . GLU A 1 69  ? 1.82783   0.97922   8.95973   1.000 83.21041  ? 29  GLU A CD  1 
ATOM   195  O OE1 . GLU A 1 69  ? 2.10815   0.38420   7.89816   1.000 83.21703  ? 29  GLU A OE1 1 
ATOM   196  O OE2 . GLU A 1 69  ? 1.20361   2.05974   8.98422   1.000 96.97714  ? 29  GLU A OE2 1 
ATOM   197  N N   . GLU A 1 70  ? 0.70542   -2.71410  11.96633  1.000 46.93264  ? 30  GLU A N   1 
ATOM   198  C CA  . GLU A 1 70  ? -0.54713  -2.77039  12.71452  1.000 43.87877  ? 30  GLU A CA  1 
ATOM   199  C C   . GLU A 1 70  ? -0.37204  -3.42067  14.08186  1.000 54.67865  ? 30  GLU A C   1 
ATOM   200  O O   . GLU A 1 70  ? -1.15831  -3.14724  14.99615  1.000 56.75789  ? 30  GLU A O   1 
ATOM   201  C CB  . GLU A 1 70  ? -1.60986  -3.51942  11.91058  1.000 51.63118  ? 30  GLU A CB  1 
ATOM   202  C CG  . GLU A 1 70  ? -2.10048  -2.78254  10.67968  1.000 57.17648  ? 30  GLU A CG  1 
ATOM   203  C CD  . GLU A 1 70  ? -2.69699  -1.43138  11.00598  1.000 64.09237  ? 30  GLU A CD  1 
ATOM   204  O OE1 . GLU A 1 70  ? -3.39520  -1.32558  12.03594  1.000 59.64688  ? 30  GLU A OE1 1 
ATOM   205  O OE2 . GLU A 1 70  ? -2.48381  -0.47957  10.22731  1.000 66.20857  ? 30  GLU A OE2 1 
ATOM   206  N N   . ALA A 1 71  ? 0.63578   -4.27284  14.24347  1.000 52.60872  ? 31  ALA A N   1 
ATOM   207  C CA  . ALA A 1 71  ? 0.88730   -4.91750  15.52668  1.000 52.35344  ? 31  ALA A CA  1 
ATOM   208  C C   . ALA A 1 71  ? 1.18211   -3.86249  16.58817  1.000 55.95596  ? 31  ALA A C   1 
ATOM   209  O O   . ALA A 1 71  ? 2.17710   -3.13109  16.46252  1.000 57.91078  ? 31  ALA A O   1 
ATOM   210  C CB  . ALA A 1 71  ? 2.05279   -5.89662  15.41230  1.000 55.17600  ? 31  ALA A CB  1 
ATOM   211  N N   . PRO A 1 72  ? 0.36342   -3.74736  17.63929  1.000 56.98558  ? 32  PRO A N   1 
ATOM   212  C CA  . PRO A 1 72  ? 0.59967   -2.68676  18.63284  1.000 50.03783  ? 32  PRO A CA  1 
ATOM   213  C C   . PRO A 1 72  ? 1.78892   -2.94201  19.54421  1.000 50.38219  ? 32  PRO A C   1 
ATOM   214  O O   . PRO A 1 72  ? 2.25085   -2.00253  20.20400  1.000 59.47120  ? 32  PRO A O   1 
ATOM   215  C CB  . PRO A 1 72  ? -0.71276  -2.65787  19.42661  1.000 57.52383  ? 32  PRO A CB  1 
ATOM   216  C CG  . PRO A 1 72  ? -1.21294  -4.07116  19.33951  1.000 51.81061  ? 32  PRO A CG  1 
ATOM   217  C CD  . PRO A 1 72  ? -0.84039  -4.54080  17.95225  1.000 46.45030  ? 32  PRO A CD  1 
ATOM   218  N N   . ASP A 1 73  ? 2.29955   -4.16826  19.60882  1.000 53.05353  ? 33  ASP A N   1 
ATOM   219  C CA  . ASP A 1 73  ? 3.43575   -4.49284  20.45911  1.000 54.17078  ? 33  ASP A CA  1 
ATOM   220  C C   . ASP A 1 73  ? 4.73421   -4.64044  19.67698  1.000 50.98232  ? 33  ASP A C   1 
ATOM   221  O O   . ASP A 1 73  ? 5.71494   -5.15484  20.22049  1.000 52.51388  ? 33  ASP A O   1 
ATOM   222  C CB  . ASP A 1 73  ? 3.15101   -5.77013  21.25200  1.000 55.52748  ? 33  ASP A CB  1 
ATOM   223  C CG  . ASP A 1 73  ? 2.67949   -6.91372  20.37183  1.000 55.32667  ? 33  ASP A CG  1 
ATOM   224  O OD1 . ASP A 1 73  ? 2.18475   -6.65419  19.25478  1.000 50.67831  ? 33  ASP A OD1 1 
ATOM   225  O OD2 . ASP A 1 73  ? 2.79810   -8.08013  20.80219  1.000 52.78018  ? 33  ASP A OD2 1 
ATOM   226  N N   . MET A 1 74  ? 4.76482   -4.20758  18.41808  1.000 45.49635  ? 34  MET A N   1 
ATOM   227  C CA  . MET A 1 74  ? 5.92486   -4.41054  17.56432  1.000 51.93464  ? 34  MET A CA  1 
ATOM   228  C C   . MET A 1 74  ? 6.25726   -3.13698  16.80229  1.000 52.89757  ? 34  MET A C   1 
ATOM   229  O O   . MET A 1 74  ? 5.37003   -2.36395  16.43125  1.000 59.20554  ? 34  MET A O   1 
ATOM   230  C CB  . MET A 1 74  ? 5.69245   -5.55182  16.56516  1.000 55.24100  ? 34  MET A CB  1 
ATOM   231  C CG  . MET A 1 74  ? 5.54976   -6.91537  17.20915  1.000 55.99402  ? 34  MET A CG  1 
ATOM   232  S SD  . MET A 1 74  ? 4.99800   -8.18297  16.05865  1.000 56.80445  ? 34  MET A SD  1 
ATOM   233  C CE  . MET A 1 74  ? 4.01547   -9.20689  17.15138  1.000 61.33049  ? 34  MET A CE  1 
ATOM   234  N N   . GLU A 1 75  ? 7.55498   -2.93500  16.57120  1.000 52.00054  ? 35  GLU A N   1 
ATOM   235  C CA  . GLU A 1 75  ? 8.06003   -1.88248  15.70202  1.000 59.60812  ? 35  GLU A CA  1 
ATOM   236  C C   . GLU A 1 75  ? 9.02863   -2.48635  14.69350  1.000 58.82241  ? 35  GLU A C   1 
ATOM   237  O O   . GLU A 1 75  ? 9.71464   -3.47314  14.97822  1.000 56.24981  ? 35  GLU A O   1 
ATOM   238  C CB  . GLU A 1 75  ? 8.76226   -0.76642  16.49413  1.000 50.62525  ? 35  GLU A CB  1 
ATOM   239  C CG  . GLU A 1 75  ? 10.18375  -1.09905  16.92076  1.000 65.29630  ? 35  GLU A CG  1 
ATOM   240  C CD  . GLU A 1 75  ? 10.90379  0.07500   17.54725  1.000 70.78008  ? 35  GLU A CD  1 
ATOM   241  O OE1 . GLU A 1 75  ? 10.65167  1.22125   17.12132  1.000 79.22451  ? 35  GLU A OE1 1 
ATOM   242  O OE2 . GLU A 1 75  ? 11.72325  -0.15045  18.46293  1.000 73.60354  ? 35  GLU A OE2 1 
ATOM   243  N N   . LEU A 1 76  ? 9.06203   -1.90087  13.49896  1.000 52.77286  ? 36  LEU A N   1 
ATOM   244  C CA  . LEU A 1 76  ? 9.88498   -2.43143  12.41866  1.000 52.38720  ? 36  LEU A CA  1 
ATOM   245  C C   . LEU A 1 76  ? 11.34295  -2.05570  12.64903  1.000 61.10107  ? 36  LEU A C   1 
ATOM   246  O O   . LEU A 1 76  ? 11.68078  -0.86885  12.71641  1.000 64.42048  ? 36  LEU A O   1 
ATOM   247  C CB  . LEU A 1 76  ? 9.41057   -1.90511  11.06646  1.000 48.03691  ? 36  LEU A CB  1 
ATOM   248  C CG  . LEU A 1 76  ? 10.23134  -2.39378  9.87104   1.000 62.21928  ? 36  LEU A CG  1 
ATOM   249  C CD1 . LEU A 1 76  ? 10.11815  -3.90634  9.72630   1.000 45.54615  ? 36  LEU A CD1 1 
ATOM   250  C CD2 . LEU A 1 76  ? 9.79666   -1.69035  8.59674   1.000 59.19320  ? 36  LEU A CD2 1 
ATOM   251  N N   . ALA A 1 77  ? 12.20640  -3.06479  12.77089  1.000 59.96293  ? 37  ALA A N   1 
ATOM   252  C CA  . ALA A 1 77  ? 13.63565  -2.79554  12.86099  1.000 52.61133  ? 37  ALA A CA  1 
ATOM   253  C C   . ALA A 1 77  ? 14.21311  -2.43230  11.49900  1.000 62.63009  ? 37  ALA A C   1 
ATOM   254  O O   . ALA A 1 77  ? 15.11444  -1.59093  11.40599  1.000 61.14255  ? 37  ALA A O   1 
ATOM   255  C CB  . ALA A 1 77  ? 14.36534  -4.00151  13.45046  1.000 53.81146  ? 37  ALA A CB  1 
ATOM   256  N N   . GLY A 1 78  ? 13.71273  -3.05399  10.44696  1.000 54.63275  ? 38  GLY A N   1 
ATOM   257  C CA  . GLY A 1 78  ? 14.22057  -2.82772  9.10917   1.000 55.41227  ? 38  GLY A CA  1 
ATOM   258  C C   . GLY A 1 78  ? 13.96885  -4.04267  8.24016   1.000 58.11910  ? 38  GLY A C   1 
ATOM   259  O O   . GLY A 1 78  ? 13.39803  -5.04267  8.67073   1.000 56.14051  ? 38  GLY A O   1 
ATOM   260  N N   . VAL A 1 79  ? 14.40721  -3.92814  6.99006   1.000 54.50743  ? 39  VAL A N   1 
ATOM   261  C CA  . VAL A 1 79  ? 14.25941  -4.98348  5.99604   1.000 53.96027  ? 39  VAL A CA  1 
ATOM   262  C C   . VAL A 1 79  ? 15.64771  -5.36446  5.50479   1.000 54.16864  ? 39  VAL A C   1 
ATOM   263  O O   . VAL A 1 79  ? 16.44805  -4.49043  5.15368   1.000 54.26674  ? 39  VAL A O   1 
ATOM   264  C CB  . VAL A 1 79  ? 13.36366  -4.54225  4.82400   1.000 50.79612  ? 39  VAL A CB  1 
ATOM   265  C CG1 . VAL A 1 79  ? 13.21765  -5.66943  3.81496   1.000 49.00261  ? 39  VAL A CG1 1 
ATOM   266  C CG2 . VAL A 1 79  ? 11.99870  -4.09665  5.33634   1.000 53.60840  ? 39  VAL A CG2 1 
ATOM   267  N N   . VAL A 1 80  ? 15.93142  -6.66345  5.48322   1.000 53.60073  ? 40  VAL A N   1 
ATOM   268  C CA  . VAL A 1 80  ? 17.21121  -7.18669  5.01966   1.000 57.02116  ? 40  VAL A CA  1 
ATOM   269  C C   . VAL A 1 80  ? 17.01289  -7.80751  3.64637   1.000 57.24244  ? 40  VAL A C   1 
ATOM   270  O O   . VAL A 1 80  ? 16.16124  -8.68704  3.47091   1.000 60.91068  ? 40  VAL A O   1 
ATOM   271  C CB  . VAL A 1 80  ? 17.78460  -8.21228  6.01112   1.000 50.65966  ? 40  VAL A CB  1 
ATOM   272  C CG1 . VAL A 1 80  ? 19.06981  -8.81658  5.46732   1.000 44.37567  ? 40  VAL A CG1 1 
ATOM   273  C CG2 . VAL A 1 80  ? 18.02255  -7.56340  7.36581   1.000 49.76391  ? 40  VAL A CG2 1 
ATOM   274  N N   . ARG A 1 81  ? 17.80214  -7.36120  2.67424   1.000 64.48804  ? 41  ARG A N   1 
ATOM   275  C CA  . ARG A 1 81  ? 17.70424  -7.86085  1.31336   1.000 57.52334  ? 41  ARG A CA  1 
ATOM   276  C C   . ARG A 1 81  ? 19.07297  -8.31188  0.82621   1.000 72.34118  ? 41  ARG A C   1 
ATOM   277  O O   . ARG A 1 81  ? 20.10645  -8.01827  1.43310   1.000 69.04003  ? 41  ARG A O   1 
ATOM   278  C CB  . ARG A 1 81  ? 17.13395  -6.79770  0.36494   1.000 62.86390  ? 41  ARG A CB  1 
ATOM   279  C CG  . ARG A 1 81  ? 15.93365  -6.04901  0.91490   1.000 64.41197  ? 41  ARG A CG  1 
ATOM   280  C CD  . ARG A 1 81  ? 15.26483  -5.22725  -0.17049  1.000 61.50101  ? 41  ARG A CD  1 
ATOM   281  N NE  . ARG A 1 81  ? 14.73713  -6.07474  -1.23343  1.000 69.31275  ? 41  ARG A NE  1 
ATOM   282  C CZ  . ARG A 1 81  ? 14.01807  -5.63415  -2.25642  1.000 64.13704  ? 41  ARG A CZ  1 
ATOM   283  N NH1 . ARG A 1 81  ? 13.72596  -4.35118  -2.39408  1.000 69.48175  ? 41  ARG A NH1 1 
ATOM   284  N NH2 . ARG A 1 81  ? 13.58499  -6.50196  -3.16649  1.000 62.82686  ? 41  ARG A NH2 1 
ATOM   285  N N   . ARG A 1 82  ? 19.06225  -9.04733  -0.28307  1.000 70.01975  ? 42  ARG A N   1 
ATOM   286  C CA  . ARG A 1 82  ? 20.29793  -9.38264  -0.97422  1.000 72.03496  ? 42  ARG A CA  1 
ATOM   287  C C   . ARG A 1 82  ? 20.96343  -8.11368  -1.49513  1.000 78.00950  ? 42  ARG A C   1 
ATOM   288  O O   . ARG A 1 82  ? 20.30347  -7.10662  -1.76526  1.000 75.87078  ? 42  ARG A O   1 
ATOM   289  C CB  . ARG A 1 82  ? 20.01408  -10.34116 -2.13331  1.000 66.71920  ? 42  ARG A CB  1 
ATOM   290  C CG  . ARG A 1 82  ? 19.49241  -11.70674 -1.71217  1.000 60.97297  ? 42  ARG A CG  1 
ATOM   291  C CD  . ARG A 1 82  ? 18.86159  -12.43986 -2.88989  1.000 64.18068  ? 42  ARG A CD  1 
ATOM   292  N NE  . ARG A 1 82  ? 17.69589  -11.72874 -3.40441  1.000 71.25184  ? 42  ARG A NE  1 
ATOM   293  C CZ  . ARG A 1 82  ? 16.99615  -12.09829 -4.46902  1.000 66.28548  ? 42  ARG A CZ  1 
ATOM   294  N NH1 . ARG A 1 82  ? 17.32769  -13.16396 -5.17901  1.000 65.65753  ? 42  ARG A NH1 1 
ATOM   295  N NH2 . ARG A 1 82  ? 15.93962  -11.37703 -4.83349  1.000 56.73608  ? 42  ARG A NH2 1 
ATOM   296  N N   . GLN A 1 83  ? 22.29206  -8.16102  -1.61962  1.000 71.37450  ? 43  GLN A N   1 
ATOM   297  C CA  . GLN A 1 83  ? 23.01982  -7.00843  -2.14300  1.000 70.42318  ? 43  GLN A CA  1 
ATOM   298  C C   . GLN A 1 83  ? 22.58859  -6.68228  -3.56639  1.000 76.56454  ? 43  GLN A C   1 
ATOM   299  O O   . GLN A 1 83  ? 22.53018  -5.50839  -3.95074  1.000 77.90940  ? 43  GLN A O   1 
ATOM   300  C CB  . GLN A 1 83  ? 24.52734  -7.25797  -2.07879  1.000 74.26831  ? 43  GLN A CB  1 
ATOM   301  C CG  . GLN A 1 83  ? 25.20432  -6.68681  -0.83873  1.000 76.27306  ? 43  GLN A CG  1 
ATOM   302  C CD  . GLN A 1 83  ? 25.16837  -5.16807  -0.80171  1.000 79.90158  ? 43  GLN A CD  1 
ATOM   303  O OE1 . GLN A 1 83  ? 24.89736  -4.51664  -1.81055  1.000 82.55860  ? 43  GLN A OE1 1 
ATOM   304  N NE2 . GLN A 1 83  ? 25.44381  -4.59706  0.36533   1.000 78.62094  ? 43  GLN A NE2 1 
ATOM   305  N N   . SER A 1 84  ? 22.29978  -7.71068  -4.36819  1.000 72.97155  ? 44  SER A N   1 
ATOM   306  C CA  . SER A 1 84  ? 21.80639  -7.48194  -5.72265  1.000 71.95492  ? 44  SER A CA  1 
ATOM   307  C C   . SER A 1 84  ? 20.51544  -6.67094  -5.71529  1.000 80.01230  ? 44  SER A C   1 
ATOM   308  O O   . SER A 1 84  ? 20.33950  -5.76545  -6.53928  1.000 81.81376  ? 44  SER A O   1 
ATOM   309  C CB  . SER A 1 84  ? 21.59928  -8.81562  -6.43881  1.000 68.07684  ? 44  SER A CB  1 
ATOM   310  O OG  . SER A 1 84  ? 20.50148  -9.52314  -5.89253  1.000 84.33034  ? 44  SER A OG  1 
ATOM   311  N N   . SER A 1 85  ? 19.60174  -6.97508  -4.78801  1.000 80.42544  ? 45  SER A N   1 
ATOM   312  C CA  . SER A 1 85  ? 18.33786  -6.25127  -4.71894  1.000 80.83374  ? 45  SER A CA  1 
ATOM   313  C C   . SER A 1 85  ? 18.50780  -4.86293  -4.12441  1.000 76.60909  ? 45  SER A C   1 
ATOM   314  O O   . SER A 1 85  ? 17.63733  -4.00541  -4.31254  1.000 75.65618  ? 45  SER A O   1 
ATOM   315  C CB  . SER A 1 85  ? 17.31768  -7.04421  -3.89957  1.000 73.66775  ? 45  SER A CB  1 
ATOM   316  O OG  . SER A 1 85  ? 17.07641  -8.31044  -4.48592  1.000 80.94623  ? 45  SER A OG  1 
ATOM   317  N N   . LEU A 1 86  ? 19.61129  -4.62728  -3.41649  1.000 80.63887  ? 46  LEU A N   1 
ATOM   318  C CA  . LEU A 1 86  ? 19.88063  -3.31438  -2.85422  1.000 70.80742  ? 46  LEU A CA  1 
ATOM   319  C C   . LEU A 1 86  ? 20.25627  -2.31482  -3.93591  1.000 82.98794  ? 46  LEU A C   1 
ATOM   320  O O   . LEU A 1 86  ? 20.23505  -1.10506  -3.68273  1.000 73.67173  ? 46  LEU A O   1 
ATOM   321  C CB  . LEU A 1 86  ? 20.98737  -3.39971  -1.80646  1.000 69.16350  ? 46  LEU A CB  1 
ATOM   322  C CG  . LEU A 1 86  ? 20.53363  -3.85583  -0.41990  1.000 72.72713  ? 46  LEU A CG  1 
ATOM   323  C CD1 . LEU A 1 86  ? 21.70656  -3.88449  0.54484   1.000 69.96075  ? 46  LEU A CD1 1 
ATOM   324  C CD2 . LEU A 1 86  ? 19.42307  -2.95921  0.09766   1.000 64.21498  ? 46  LEU A CD2 1 
ATOM   325  N N   . GLU A 1 87  ? 20.59807  -2.79656  -5.13344  1.000 87.89981  ? 47  GLU A N   1 
ATOM   326  C CA  . GLU A 1 87  ? 21.06070  -1.94148  -6.21572  1.000 82.44995  ? 47  GLU A CA  1 
ATOM   327  C C   . GLU A 1 87  ? 19.94468  -1.51471  -7.16019  1.000 90.76371  ? 47  GLU A C   1 
ATOM   328  O O   . GLU A 1 87  ? 20.15175  -0.60005  -7.96694  1.000 100.47427 ? 47  GLU A O   1 
ATOM   329  C CB  . GLU A 1 87  ? 22.09509  -2.70068  -7.05601  1.000 83.15188  ? 47  GLU A CB  1 
ATOM   330  C CG  . GLU A 1 87  ? 23.19222  -3.41095  -6.27903  1.000 95.07991  ? 47  GLU A CG  1 
ATOM   331  C CD  . GLU A 1 87  ? 24.27118  -2.49510  -5.76125  1.000 101.74998 ? 47  GLU A CD  1 
ATOM   332  O OE1 . GLU A 1 87  ? 24.23488  -1.28412  -6.06179  1.000 104.45879 ? 47  GLU A OE1 1 
ATOM   333  O OE2 . GLU A 1 87  ? 25.16609  -2.99889  -5.05146  1.000 104.64210 ? 47  GLU A OE2 1 
ATOM   334  N N   . LYS A 1 88  ? 18.77773  -2.14626  -7.07754  1.000 90.01714  ? 48  LYS A N   1 
ATOM   335  C CA  . LYS A 1 88  ? 17.57653  -1.68418  -7.75156  1.000 87.51902  ? 48  LYS A CA  1 
ATOM   336  C C   . LYS A 1 88  ? 16.95472  -0.50069  -7.01504  1.000 93.74484  ? 48  LYS A C   1 
ATOM   337  O O   . LYS A 1 88  ? 17.21628  -0.28912  -5.82792  1.000 97.81505  ? 48  LYS A O   1 
ATOM   338  C CB  . LYS A 1 88  ? 16.58415  -2.83770  -7.88364  1.000 88.85931  ? 48  LYS A CB  1 
ATOM   339  C CG  . LYS A 1 88  ? 17.13083  -3.99021  -8.72618  1.000 95.60730  ? 48  LYS A CG  1 
ATOM   340  C CD  . LYS A 1 88  ? 16.19321  -5.18832  -8.77959  1.000 96.66166  ? 48  LYS A CD  1 
ATOM   341  C CE  . LYS A 1 88  ? 15.82985  -5.69073  -7.39492  1.000 96.15217  ? 48  LYS A CE  1 
ATOM   342  N NZ  . LYS A 1 88  ? 14.90342  -6.84776  -7.51452  1.000 99.23212  ? 48  LYS A NZ  1 
ATOM   343  N N   . PRO A 1 89  ? 16.12288  0.28687   -7.70140  1.000 97.23947  ? 49  PRO A N   1 
ATOM   344  C CA  . PRO A 1 89  ? 15.52438  1.46508   -7.06130  1.000 92.63386  ? 49  PRO A CA  1 
ATOM   345  C C   . PRO A 1 89  ? 14.71581  1.11327   -5.82038  1.000 87.40469  ? 49  PRO A C   1 
ATOM   346  O O   . PRO A 1 89  ? 14.07353  0.06440   -5.73969  1.000 91.57812  ? 49  PRO A O   1 
ATOM   347  C CB  . PRO A 1 89  ? 14.63225  2.05123   -8.16224  1.000 82.42535  ? 49  PRO A CB  1 
ATOM   348  C CG  . PRO A 1 89  ? 15.24238  1.57071   -9.43089  1.000 87.21151  ? 49  PRO A CG  1 
ATOM   349  C CD  . PRO A 1 89  ? 15.77329  0.20373   -9.13111  1.000 94.95025  ? 49  PRO A CD  1 
ATOM   350  N N   . LEU A 1 90  ? 14.75990  2.01356   -4.84900  1.000 80.33813  ? 50  LEU A N   1 
ATOM   351  C CA  . LEU A 1 90  ? 14.10256  1.79382   -3.56656  1.000 80.16781  ? 50  LEU A CA  1 
ATOM   352  C C   . LEU A 1 90  ? 12.59055  1.82211   -3.73873  1.000 91.81659  ? 50  LEU A C   1 
ATOM   353  O O   . LEU A 1 90  ? 12.05643  2.80723   -4.26557  1.000 95.98345  ? 50  LEU A O   1 
ATOM   354  C CB  . LEU A 1 90  ? 14.53513  2.85578   -2.56125  1.000 87.99241  ? 50  LEU A CB  1 
ATOM   355  C CG  . LEU A 1 90  ? 13.83793  2.83024   -1.19814  1.000 79.74413  ? 50  LEU A CG  1 
ATOM   356  C CD1 . LEU A 1 90  ? 14.29961  1.63753   -0.37971  1.000 76.56772  ? 50  LEU A CD1 1 
ATOM   357  C CD2 . LEU A 1 90  ? 14.07727  4.12830   -0.43882  1.000 66.53344  ? 50  LEU A CD2 1 
ATOM   358  N N   . PRO A 1 91  ? 11.86922  0.77620   -3.33470  1.000 87.10029  ? 51  PRO A N   1 
ATOM   359  C CA  . PRO A 1 91  ? 10.40695  0.80341   -3.44728  1.000 85.76198  ? 51  PRO A CA  1 
ATOM   360  C C   . PRO A 1 91  ? 9.80820   1.95847   -2.65792  1.000 88.33433  ? 51  PRO A C   1 
ATOM   361  O O   . PRO A 1 91  ? 10.31886  2.35841   -1.60851  1.000 83.79936  ? 51  PRO A O   1 
ATOM   362  C CB  . PRO A 1 91  ? 9.98162   -0.55110  -2.87012  1.000 75.89122  ? 51  PRO A CB  1 
ATOM   363  C CG  . PRO A 1 91  ? 11.18430  -1.42761  -3.04875  1.000 82.42787  ? 51  PRO A CG  1 
ATOM   364  C CD  . PRO A 1 91  ? 12.35931  -0.51642  -2.82637  1.000 87.12543  ? 51  PRO A CD  1 
ATOM   365  N N   . ARG A 1 92  ? 8.70271   2.49269   -3.18265  1.000 89.95575  ? 52  ARG A N   1 
ATOM   366  C CA  . ARG A 1 92  ? 8.13882   3.72404   -2.63983  1.000 84.64200  ? 52  ARG A CA  1 
ATOM   367  C C   . ARG A 1 92  ? 7.61659   3.54024   -1.22027  1.000 88.25109  ? 52  ARG A C   1 
ATOM   368  O O   . ARG A 1 92  ? 7.59676   4.50020   -0.44116  1.000 80.42874  ? 52  ARG A O   1 
ATOM   369  C CB  . ARG A 1 92  ? 7.01587   4.23035   -3.54367  1.000 94.99181  ? 52  ARG A CB  1 
ATOM   370  C CG  . ARG A 1 92  ? 6.86768   3.47545   -4.85786  1.000 103.95558 ? 52  ARG A CG  1 
ATOM   371  C CD  . ARG A 1 92  ? 7.69853   4.09621   -5.97212  1.000 117.98837 ? 52  ARG A CD  1 
ATOM   372  N NE  . ARG A 1 92  ? 9.07063   3.60354   -5.99413  1.000 123.36679 ? 52  ARG A NE  1 
ATOM   373  C CZ  . ARG A 1 92  ? 9.49569   2.61754   -6.77213  1.000 120.77411 ? 52  ARG A CZ  1 
ATOM   374  N NH1 . ARG A 1 92  ? 8.67840   1.99386   -7.60451  1.000 113.79662 ? 52  ARG A NH1 1 
ATOM   375  N NH2 . ARG A 1 92  ? 10.77319  2.25137   -6.71704  1.000 109.00004 ? 52  ARG A NH2 1 
ATOM   376  N N   . GLU A 1 93  ? 7.18437   2.32995   -0.86662  1.000 85.67553  ? 53  GLU A N   1 
ATOM   377  C CA  . GLU A 1 93  ? 6.65667   2.07937   0.46796   1.000 71.91030  ? 53  GLU A CA  1 
ATOM   378  C C   . GLU A 1 93  ? 7.74786   1.89375   1.51337   1.000 74.82298  ? 53  GLU A C   1 
ATOM   379  O O   . GLU A 1 93  ? 7.43895   1.87729   2.70983   1.000 72.48419  ? 53  GLU A O   1 
ATOM   380  C CB  . GLU A 1 93  ? 5.74635   0.84729   0.45510   1.000 64.95243  ? 53  GLU A CB  1 
ATOM   381  C CG  . GLU A 1 93  ? 6.45797   -0.46463  0.17097   1.000 61.94502  ? 53  GLU A CG  1 
ATOM   382  C CD  . GLU A 1 93  ? 6.64810   -0.74107  -1.30747  1.000 78.44409  ? 53  GLU A CD  1 
ATOM   383  O OE1 . GLU A 1 93  ? 6.44345   0.17935   -2.12583  1.000 85.73532  ? 53  GLU A OE1 1 
ATOM   384  O OE2 . GLU A 1 93  ? 7.00620   -1.88709  -1.64807  1.000 70.46886  ? 53  GLU A OE2 1 
ATOM   385  N N   . LEU A 1 94  ? 9.00449   1.75025   1.09812   1.000 68.26111  ? 54  LEU A N   1 
ATOM   386  C CA  . LEU A 1 94  ? 10.11967  1.59183   2.01955   1.000 69.31089  ? 54  LEU A CA  1 
ATOM   387  C C   . LEU A 1 94  ? 10.81715  2.90872   2.33596   1.000 69.22280  ? 54  LEU A C   1 
ATOM   388  O O   . LEU A 1 94  ? 11.89885  2.89402   2.93184   1.000 64.81379  ? 54  LEU A O   1 
ATOM   389  C CB  . LEU A 1 94  ? 11.12933  0.58483   1.46372   1.000 74.14870  ? 54  LEU A CB  1 
ATOM   390  C CG  . LEU A 1 94  ? 10.66403  -0.87039  1.37661   1.000 63.62960  ? 54  LEU A CG  1 
ATOM   391  C CD1 . LEU A 1 94  ? 11.80261  -1.76831  0.92431   1.000 58.08931  ? 54  LEU A CD1 1 
ATOM   392  C CD2 . LEU A 1 94  ? 10.11930  -1.33738  2.71529   1.000 61.98058  ? 54  LEU A CD2 1 
ATOM   393  N N   . HIS A 1 95  ? 10.23437  4.04059   1.94281   1.000 78.62881  ? 55  HIS A N   1 
ATOM   394  C CA  . HIS A 1 95  ? 10.79319  5.33326   2.31633   1.000 84.24852  ? 55  HIS A CA  1 
ATOM   395  C C   . HIS A 1 95  ? 10.75028  5.49784   3.83008   1.000 74.84364  ? 55  HIS A C   1 
ATOM   396  O O   . HIS A 1 95  ? 9.70514   5.30653   4.45890   1.000 80.55741  ? 55  HIS A O   1 
ATOM   397  C CB  . HIS A 1 95  ? 10.02637  6.46793   1.63312   1.000 84.82935  ? 55  HIS A CB  1 
ATOM   398  C CG  . HIS A 1 95  ? 10.42344  6.69641   0.20708   1.000 94.57966  ? 55  HIS A CG  1 
ATOM   399  N ND1 . HIS A 1 95  ? 11.06047  5.73787   -0.55164  1.000 93.18747  ? 55  HIS A ND1 1 
ATOM   400  C CD2 . HIS A 1 95  ? 10.28083  7.77801   -0.59575  1.000 95.00014  ? 55  HIS A CD2 1 
ATOM   401  C CE1 . HIS A 1 95  ? 11.28938  6.21728   -1.76126  1.000 85.56431  ? 55  HIS A CE1 1 
ATOM   402  N NE2 . HIS A 1 95  ? 10.82631  7.45333   -1.81416  1.000 90.41574  ? 55  HIS A NE2 1 
ATOM   403  N N   . GLY A 1 96  ? 11.89198  5.85551   4.41381   1.000 68.72880  ? 56  GLY A N   1 
ATOM   404  C CA  . GLY A 1 96  ? 12.00858  5.93686   5.85445   1.000 65.78966  ? 56  GLY A CA  1 
ATOM   405  C C   . GLY A 1 96  ? 12.23321  4.61532   6.55112   1.000 67.03071  ? 56  GLY A C   1 
ATOM   406  O O   . GLY A 1 96  ? 12.16580  4.56399   7.78448   1.000 72.20698  ? 56  GLY A O   1 
ATOM   407  N N   . VAL A 1 97  ? 12.49045  3.54515   5.80398   1.000 60.84774  ? 57  VAL A N   1 
ATOM   408  C CA  . VAL A 1 97  ? 12.71895  2.21642   6.35800   1.000 67.35951  ? 57  VAL A CA  1 
ATOM   409  C C   . VAL A 1 97  ? 14.17564  1.84164   6.13048   1.000 55.79421  ? 57  VAL A C   1 
ATOM   410  O O   . VAL A 1 97  ? 14.69283  1.98488   5.01621   1.000 59.31118  ? 57  VAL A O   1 
ATOM   411  C CB  . VAL A 1 97  ? 11.78007  1.17657   5.72282   1.000 67.13780  ? 57  VAL A CB  1 
ATOM   412  C CG1 . VAL A 1 97  ? 12.14848  -0.22638  6.18169   1.000 62.52688  ? 57  VAL A CG1 1 
ATOM   413  C CG2 . VAL A 1 97  ? 10.32827  1.49975   6.05422   1.000 63.71219  ? 57  VAL A CG2 1 
ATOM   414  N N   . SER A 1 98  ? 14.83809  1.37549   7.18588   1.000 54.63882  ? 58  SER A N   1 
ATOM   415  C CA  . SER A 1 98  ? 16.21673  0.90906   7.07792   1.000 55.49063  ? 58  SER A CA  1 
ATOM   416  C C   . SER A 1 98  ? 16.25275  -0.37165  6.25131   1.000 57.62414  ? 58  SER A C   1 
ATOM   417  O O   . SER A 1 98  ? 15.75365  -1.41299  6.68716   1.000 56.51899  ? 58  SER A O   1 
ATOM   418  C CB  . SER A 1 98  ? 16.80468  0.68502   8.46700   1.000 55.71744  ? 58  SER A CB  1 
ATOM   419  O OG  . SER A 1 98  ? 16.75310  1.87428   9.23490   1.000 66.45510  ? 58  SER A OG  1 
ATOM   420  N N   . VAL A 1 99  ? 16.83692  -0.30042  5.05817   1.000 57.56832  ? 59  VAL A N   1 
ATOM   421  C CA  . VAL A 1 99  ? 16.96159  -1.44494  4.16006   1.000 59.77107  ? 59  VAL A CA  1 
ATOM   422  C C   . VAL A 1 99  ? 18.44583  -1.75700  4.00958   1.000 56.37349  ? 59  VAL A C   1 
ATOM   423  O O   . VAL A 1 99  ? 19.19152  -0.97857  3.40117   1.000 60.22729  ? 59  VAL A O   1 
ATOM   424  C CB  . VAL A 1 99  ? 16.30993  -1.17749  2.79647   1.000 58.54090  ? 59  VAL A CB  1 
ATOM   425  C CG1 . VAL A 1 99  ? 16.27720  -2.44989  1.96415   1.000 68.04042  ? 59  VAL A CG1 1 
ATOM   426  C CG2 . VAL A 1 99  ? 14.90640  -0.61516  2.97945   1.000 54.78073  ? 59  VAL A CG2 1 
ATOM   427  N N   . VAL A 1 100 ? 18.87759  -2.89346  4.55752   1.000 62.22030  ? 60  VAL A N   1 
ATOM   428  C CA  . VAL A 1 100 ? 20.28570  -3.25393  4.63841   1.000 62.57088  ? 60  VAL A CA  1 
ATOM   429  C C   . VAL A 1 100 ? 20.47344  -4.66471  4.08574   1.000 66.72760  ? 60  VAL A C   1 
ATOM   430  O O   . VAL A 1 100 ? 19.52289  -5.32230  3.66502   1.000 69.96859  ? 60  VAL A O   1 
ATOM   431  C CB  . VAL A 1 100 ? 20.83034  -3.15649  6.07821   1.000 56.36258  ? 60  VAL A CB  1 
ATOM   432  C CG1 . VAL A 1 100 ? 20.67807  -1.74562  6.60905   1.000 49.87568  ? 60  VAL A CG1 1 
ATOM   433  C CG2 . VAL A 1 100 ? 20.09824  -4.13842  6.97396   1.000 60.49702  ? 60  VAL A CG2 1 
ATOM   434  N N   . SER A 1 101 ? 21.72852  -5.11964  4.08633   1.000 52.21731  ? 61  SER A N   1 
ATOM   435  C CA  . SER A 1 101 ? 22.09380  -6.43752  3.58239   1.000 64.20162  ? 61  SER A CA  1 
ATOM   436  C C   . SER A 1 101 ? 22.37349  -7.44993  4.68699   1.000 63.91087  ? 61  SER A C   1 
ATOM   437  O O   . SER A 1 101 ? 22.49381  -8.64404  4.39154   1.000 59.72625  ? 61  SER A O   1 
ATOM   438  C CB  . SER A 1 101 ? 23.32299  -6.33835  2.66783   1.000 68.15358  ? 61  SER A CB  1 
ATOM   439  O OG  . SER A 1 101 ? 24.47622  -5.96072  3.39892   1.000 75.47018  ? 61  SER A OG  1 
ATOM   440  N N   . ASP A 1 102 ? 22.48492  -7.01015  5.93951   1.000 66.64446  ? 62  ASP A N   1 
ATOM   441  C CA  . ASP A 1 102 ? 22.71251  -7.91748  7.05411   1.000 61.17784  ? 62  ASP A CA  1 
ATOM   442  C C   . ASP A 1 102 ? 22.03029  -7.35808  8.29326   1.000 60.17462  ? 62  ASP A C   1 
ATOM   443  O O   . ASP A 1 102 ? 21.96479  -6.14172  8.48644   1.000 63.92925  ? 62  ASP A O   1 
ATOM   444  C CB  . ASP A 1 102 ? 24.20741  -8.12756  7.31857   1.000 63.89745  ? 62  ASP A CB  1 
ATOM   445  C CG  . ASP A 1 102 ? 24.46626  -9.11920  8.43563   1.000 72.11845  ? 62  ASP A CG  1 
ATOM   446  O OD1 . ASP A 1 102 ? 24.26158  -10.33215 8.21702   1.000 84.54368  ? 62  ASP A OD1 1 
ATOM   447  O OD2 . ASP A 1 102 ? 24.86536  -8.68613  9.53635   1.000 70.49274  ? 62  ASP A OD2 1 
ATOM   448  N N   . VAL A 1 103 ? 21.53505  -8.26513  9.13977   1.000 61.29596  ? 63  VAL A N   1 
ATOM   449  C CA  . VAL A 1 103 ? 20.76308  -7.87413  10.31447  1.000 67.79802  ? 63  VAL A CA  1 
ATOM   450  C C   . VAL A 1 103 ? 21.59088  -7.05472  11.29769  1.000 57.66826  ? 63  VAL A C   1 
ATOM   451  O O   . VAL A 1 103 ? 21.03314  -6.27079  12.07438  1.000 54.36461  ? 63  VAL A O   1 
ATOM   452  C CB  . VAL A 1 103 ? 20.18130  -9.14216  10.98268  1.000 57.68514  ? 63  VAL A CB  1 
ATOM   453  C CG1 . VAL A 1 103 ? 19.31574  -8.79548  12.18469  1.000 52.58173  ? 63  VAL A CG1 1 
ATOM   454  C CG2 . VAL A 1 103 ? 19.37673  -9.93577  9.97705   1.000 56.49152  ? 63  VAL A CG2 1 
ATOM   455  N N   . SER A 1 104 ? 22.91869  -7.19032  11.26530  1.000 54.89450  ? 64  SER A N   1 
ATOM   456  C CA  . SER A 1 104 ? 23.75751  -6.47160  12.21901  1.000 65.70053  ? 64  SER A CA  1 
ATOM   457  C C   . SER A 1 104 ? 23.67850  -4.96108  12.04330  1.000 62.56680  ? 64  SER A C   1 
ATOM   458  O O   . SER A 1 104 ? 23.96773  -4.22292  12.99128  1.000 69.42311  ? 64  SER A O   1 
ATOM   459  C CB  . SER A 1 104 ? 25.21119  -6.92783  12.10015  1.000 57.43564  ? 64  SER A CB  1 
ATOM   460  O OG  . SER A 1 104 ? 25.70804  -6.70178  10.79344  1.000 67.24261  ? 64  SER A OG  1 
ATOM   461  N N   . ALA A 1 105 ? 23.29731  -4.48502  10.86012  1.000 54.30404  ? 65  ALA A N   1 
ATOM   462  C CA  . ALA A 1 105 ? 23.21791  -3.05431  10.60173  1.000 58.59475  ? 65  ALA A CA  1 
ATOM   463  C C   . ALA A 1 105 ? 21.91302  -2.43025  11.08272  1.000 60.60326  ? 65  ALA A C   1 
ATOM   464  O O   . ALA A 1 105 ? 21.71587  -1.22510  10.89308  1.000 53.50570  ? 65  ALA A O   1 
ATOM   465  C CB  . ALA A 1 105 ? 23.39863  -2.78541  9.10503   1.000 49.90312  ? 65  ALA A CB  1 
ATOM   466  N N   . LEU A 1 106 ? 21.02156  -3.20636  11.69597  1.000 59.01835  ? 66  LEU A N   1 
ATOM   467  C CA  . LEU A 1 106 ? 19.73472  -2.69929  12.15175  1.000 64.57231  ? 66  LEU A CA  1 
ATOM   468  C C   . LEU A 1 106 ? 19.67952  -2.48771  13.65866  1.000 61.46236  ? 66  LEU A C   1 
ATOM   469  O O   . LEU A 1 106 ? 18.60445  -2.19718  14.19175  1.000 63.35870  ? 66  LEU A O   1 
ATOM   470  C CB  . LEU A 1 106 ? 18.61262  -3.64967  11.73007  1.000 58.93832  ? 66  LEU A CB  1 
ATOM   471  C CG  . LEU A 1 106 ? 18.37798  -3.83497  10.23214  1.000 58.87749  ? 66  LEU A CG  1 
ATOM   472  C CD1 . LEU A 1 106 ? 17.22130  -4.79170  9.99711   1.000 58.97906  ? 66  LEU A CD1 1 
ATOM   473  C CD2 . LEU A 1 106 ? 18.11868  -2.49994  9.55996   1.000 61.47315  ? 66  LEU A CD2 1 
ATOM   474  N N   . GLY A 1 107 ? 20.80451  -2.61816  14.35717  1.000 59.70048  ? 67  GLY A N   1 
ATOM   475  C CA  . GLY A 1 107 ? 20.73237  -2.50443  15.79852  1.000 61.62888  ? 67  GLY A CA  1 
ATOM   476  C C   . GLY A 1 107 ? 20.09667  -3.73245  16.43258  1.000 60.33497  ? 67  GLY A C   1 
ATOM   477  O O   . GLY A 1 107 ? 20.21997  -4.86076  15.94415  1.000 50.24100  ? 67  GLY A O   1 
ATOM   478  N N   . GLN A 1 108 ? 19.40464  -3.49943  17.54671  1.000 58.53177  ? 68  GLN A N   1 
ATOM   479  C CA  . GLN A 1 108 ? 18.74127  -4.57502  18.27419  1.000 62.53260  ? 68  GLN A CA  1 
ATOM   480  C C   . GLN A 1 108 ? 17.57694  -5.15075  17.47832  1.000 63.58253  ? 68  GLN A C   1 
ATOM   481  O O   . GLN A 1 108 ? 16.68836  -4.41846  17.03307  1.000 69.27511  ? 68  GLN A O   1 
ATOM   482  C CB  . GLN A 1 108 ? 18.24459  -4.07282  19.63009  1.000 61.40774  ? 68  GLN A CB  1 
ATOM   483  C CG  . GLN A 1 108 ? 17.20749  -4.98235  20.29878  1.000 66.93634  ? 68  GLN A CG  1 
ATOM   484  C CD  . GLN A 1 108 ? 17.76307  -6.30875  20.80740  1.000 82.78457  ? 68  GLN A CD  1 
ATOM   485  O OE1 . GLN A 1 108 ? 18.82185  -6.77118  20.38077  1.000 94.04137  ? 68  GLN A OE1 1 
ATOM   486  N NE2 . GLN A 1 108 ? 17.03326  -6.93086  21.72597  1.000 81.35823  ? 68  GLN A NE2 1 
ATOM   487  N N   . VAL A 1 109 ? 17.58918  -6.46927  17.29841  1.000 62.34777  ? 69  VAL A N   1 
ATOM   488  C CA  . VAL A 1 109 ? 16.53389  -7.19394  16.59912  1.000 56.88223  ? 69  VAL A CA  1 
ATOM   489  C C   . VAL A 1 109 ? 16.07509  -8.33597  17.49509  1.000 55.33611  ? 69  VAL A C   1 
ATOM   490  O O   . VAL A 1 109 ? 16.86175  -9.23961  17.80293  1.000 64.08112  ? 69  VAL A O   1 
ATOM   491  C CB  . VAL A 1 109 ? 17.00101  -7.72470  15.23351  1.000 56.10645  ? 69  VAL A CB  1 
ATOM   492  C CG1 . VAL A 1 109 ? 15.92924  -8.60512  14.60980  1.000 50.73677  ? 69  VAL A CG1 1 
ATOM   493  C CG2 . VAL A 1 109 ? 17.34060  -6.56648  14.31180  1.000 63.95207  ? 69  VAL A CG2 1 
ATOM   494  N N   . ASP A 1 110 ? 14.81155  -8.28971  17.92542  1.000 58.69173  ? 70  ASP A N   1 
ATOM   495  C CA  . ASP A 1 110 ? 14.27277  -9.36003  18.75980  1.000 50.43120  ? 70  ASP A CA  1 
ATOM   496  C C   . ASP A 1 110 ? 13.89942  -10.58355 17.93068  1.000 47.71628  ? 70  ASP A C   1 
ATOM   497  O O   . ASP A 1 110 ? 14.29188  -11.70811 18.26022  1.000 52.95607  ? 70  ASP A O   1 
ATOM   498  C CB  . ASP A 1 110 ? 13.05410  -8.86045  19.54044  1.000 50.91946  ? 70  ASP A CB  1 
ATOM   499  C CG  . ASP A 1 110 ? 13.40258  -7.77004  20.53004  1.000 58.15207  ? 70  ASP A CG  1 
ATOM   500  O OD1 . ASP A 1 110 ? 14.28281  -8.00720  21.38220  1.000 55.32318  ? 70  ASP A OD1 1 
ATOM   501  O OD2 . ASP A 1 110 ? 12.79517  -6.68007  20.45890  1.000 60.99828  ? 70  ASP A OD2 1 
ATOM   502  N N   . VAL A 1 111 ? 13.14697  -10.38615 16.85148  1.000 44.30984  ? 71  VAL A N   1 
ATOM   503  C CA  . VAL A 1 111 ? 12.63725  -11.48121 16.03610  1.000 47.16646  ? 71  VAL A CA  1 
ATOM   504  C C   . VAL A 1 111 ? 12.94179  -11.18824 14.57406  1.000 45.77201  ? 71  VAL A C   1 
ATOM   505  O O   . VAL A 1 111 ? 12.81393  -10.04570 14.11871  1.000 46.54107  ? 71  VAL A O   1 
ATOM   506  C CB  . VAL A 1 111 ? 11.12064  -11.69909 16.24444  1.000 49.27573  ? 71  VAL A CB  1 
ATOM   507  C CG1 . VAL A 1 111 ? 10.61984  -12.84327 15.37559  1.000 49.20161  ? 71  VAL A CG1 1 
ATOM   508  C CG2 . VAL A 1 111 ? 10.80923  -11.97860 17.70866  1.000 40.66215  ? 71  VAL A CG2 1 
ATOM   509  N N   . ALA A 1 112 ? 13.35484  -12.21975 13.84283  1.000 45.14440  ? 72  ALA A N   1 
ATOM   510  C CA  . ALA A 1 112 ? 13.53340  -12.14343 12.40067  1.000 45.54914  ? 72  ALA A CA  1 
ATOM   511  C C   . ALA A 1 112 ? 12.43207  -12.94715 11.72403  1.000 54.68356  ? 72  ALA A C   1 
ATOM   512  O O   . ALA A 1 112 ? 12.27006  -14.14183 11.99705  1.000 48.12711  ? 72  ALA A O   1 
ATOM   513  C CB  . ALA A 1 112 ? 14.90764  -12.67132 11.98545  1.000 39.26756  ? 72  ALA A CB  1 
ATOM   514  N N   . VAL A 1 113 ? 11.68624  -12.29475 10.84006  1.000 49.64022  ? 73  VAL A N   1 
ATOM   515  C CA  . VAL A 1 113 ? 10.59486  -12.92595 10.10967  1.000 50.53865  ? 73  VAL A CA  1 
ATOM   516  C C   . VAL A 1 113 ? 11.13021  -13.29385 8.73502   1.000 47.65070  ? 73  VAL A C   1 
ATOM   517  O O   . VAL A 1 113 ? 11.45467  -12.41808 7.92520   1.000 50.49680  ? 73  VAL A O   1 
ATOM   518  C CB  . VAL A 1 113 ? 9.37134   -12.00731 10.01039  1.000 48.53470  ? 73  VAL A CB  1 
ATOM   519  C CG1 . VAL A 1 113 ? 8.33147   -12.61620 9.08167   1.000 46.25437  ? 73  VAL A CG1 1 
ATOM   520  C CG2 . VAL A 1 113 ? 8.78399   -11.76464 11.39192  1.000 43.56674  ? 73  VAL A CG2 1 
ATOM   521  N N   . LEU A 1 114 ? 11.23177  -14.59154 8.47285   1.000 47.31729  ? 74  LEU A N   1 
ATOM   522  C CA  . LEU A 1 114 ? 11.93116  -15.09129 7.29511   1.000 55.22744  ? 74  LEU A CA  1 
ATOM   523  C C   . LEU A 1 114 ? 10.94668  -15.21200 6.13848   1.000 48.38164  ? 74  LEU A C   1 
ATOM   524  O O   . LEU A 1 114 ? 10.13822  -16.14525 6.09580   1.000 63.53599  ? 74  LEU A O   1 
ATOM   525  C CB  . LEU A 1 114 ? 12.60146  -16.42869 7.59815   1.000 52.23559  ? 74  LEU A CB  1 
ATOM   526  C CG  . LEU A 1 114 ? 13.99749  -16.41085 8.23436   1.000 51.84641  ? 74  LEU A CG  1 
ATOM   527  C CD1 . LEU A 1 114 ? 14.12244  -15.38494 9.35288   1.000 51.72835  ? 74  LEU A CD1 1 
ATOM   528  C CD2 . LEU A 1 114 ? 14.34468  -17.79470 8.74733   1.000 53.09090  ? 74  LEU A CD2 1 
ATOM   529  N N   . CYS A 1 115 ? 11.03029  -14.27582 5.19298   1.000 47.43761  ? 75  CYS A N   1 
ATOM   530  C CA  . CYS A 1 115 ? 10.18614  -14.29800 4.00653   1.000 47.55262  ? 75  CYS A CA  1 
ATOM   531  C C   . CYS A 1 115 ? 11.02742  -14.67770 2.79687   1.000 52.28737  ? 75  CYS A C   1 
ATOM   532  O O   . CYS A 1 115 ? 10.95074  -14.03555 1.74566   1.000 50.32784  ? 75  CYS A O   1 
ATOM   533  C CB  . CYS A 1 115 ? 9.51413   -12.93899 3.80572   1.000 55.52147  ? 75  CYS A CB  1 
ATOM   534  S SG  . CYS A 1 115 ? 8.85997   -12.20336 5.32274   1.000 55.23832  ? 75  CYS A SG  1 
ATOM   535  N N   . THR A 1 116 ? 11.83320  -15.71465 2.94858   1.000 56.67737  ? 76  THR A N   1 
ATOM   536  C CA  . THR A 1 116 ? 12.80306  -16.17296 1.97214   1.000 51.17196  ? 76  THR A CA  1 
ATOM   537  C C   . THR A 1 116 ? 12.30575  -17.43709 1.28667   1.000 57.19168  ? 76  THR A C   1 
ATOM   538  O O   . THR A 1 116 ? 11.37208  -18.08780 1.76617   1.000 49.71594  ? 76  THR A O   1 
ATOM   539  C CB  . THR A 1 116 ? 14.14568  -16.44424 2.66251   1.000 53.94013  ? 76  THR A CB  1 
ATOM   540  O OG1 . THR A 1 116 ? 13.93210  -17.27990 3.80653   1.000 53.88135  ? 76  THR A OG1 1 
ATOM   541  C CG2 . THR A 1 116 ? 14.79201  -15.13611 3.11040   1.000 43.21756  ? 76  THR A CG2 1 
ATOM   542  N N   . PRO A 1 117 ? 12.90225  -17.82084 0.15509   1.000 59.48450  ? 77  PRO A N   1 
ATOM   543  C CA  . PRO A 1 117 ? 12.46046  -19.04804 -0.51673  1.000 50.35555  ? 77  PRO A CA  1 
ATOM   544  C C   . PRO A 1 117 ? 12.65966  -20.26625 0.37213   1.000 62.79827  ? 77  PRO A C   1 
ATOM   545  O O   . PRO A 1 117 ? 13.53819  -20.29526 1.23793   1.000 57.69038  ? 77  PRO A O   1 
ATOM   546  C CB  . PRO A 1 117 ? 13.34473  -19.10986 -1.76686  1.000 60.22499  ? 77  PRO A CB  1 
ATOM   547  C CG  . PRO A 1 117 ? 13.72326  -17.69233 -2.02146  1.000 61.94381  ? 77  PRO A CG  1 
ATOM   548  C CD  . PRO A 1 117 ? 13.86158  -17.06257 -0.66884  1.000 48.62622  ? 77  PRO A CD  1 
ATOM   549  N N   . THR A 1 118 ? 11.80968  -21.27299 0.14778   1.000 57.16697  ? 78  THR A N   1 
ATOM   550  C CA  . THR A 1 118 ? 11.73810  -22.43224 1.03339   1.000 63.74887  ? 78  THR A CA  1 
ATOM   551  C C   . THR A 1 118 ? 13.10491  -23.07102 1.24865   1.000 61.32074  ? 78  THR A C   1 
ATOM   552  O O   . THR A 1 118 ? 13.53066  -23.28666 2.38893   1.000 59.55970  ? 78  THR A O   1 
ATOM   553  C CB  . THR A 1 118 ? 10.75841  -23.45446 0.45993   1.000 64.18355  ? 78  THR A CB  1 
ATOM   554  O OG1 . THR A 1 118 ? 9.46123   -22.85802 0.34099   1.000 67.40673  ? 78  THR A OG1 1 
ATOM   555  C CG2 . THR A 1 118 ? 10.67043  -24.65414 1.36947   1.000 55.56413  ? 78  THR A CG2 1 
ATOM   556  N N   . TYR A 1 119 ? 13.81011  -23.37815 0.15918   1.000 68.15783  ? 79  TYR A N   1 
ATOM   557  C CA  . TYR A 1 119 ? 15.07903  -24.08747 0.27264   1.000 69.19731  ? 79  TYR A CA  1 
ATOM   558  C C   . TYR A 1 119 ? 16.16369  -23.23408 0.91488   1.000 64.59365  ? 79  TYR A C   1 
ATOM   559  O O   . TYR A 1 119 ? 17.12045  -23.78391 1.47014   1.000 69.26115  ? 79  TYR A O   1 
ATOM   560  C CB  . TYR A 1 119 ? 15.53833  -24.58178 -1.10039  1.000 65.66638  ? 79  TYR A CB  1 
ATOM   561  C CG  . TYR A 1 119 ? 14.74315  -25.76513 -1.60658  1.000 88.24385  ? 79  TYR A CG  1 
ATOM   562  C CD1 . TYR A 1 119 ? 14.73363  -26.96747 -0.90982  1.000 93.94432  ? 79  TYR A CD1 1 
ATOM   563  C CD2 . TYR A 1 119 ? 14.00624  -25.68417 -2.78038  1.000 89.80946  ? 79  TYR A CD2 1 
ATOM   564  C CE1 . TYR A 1 119 ? 14.00907  -28.05453 -1.36431  1.000 97.26449  ? 79  TYR A CE1 1 
ATOM   565  C CE2 . TYR A 1 119 ? 13.27779  -26.76788 -3.24426  1.000 93.82916  ? 79  TYR A CE2 1 
ATOM   566  C CZ  . TYR A 1 119 ? 13.28302  -27.95041 -2.53178  1.000 101.46400 ? 79  TYR A CZ  1 
ATOM   567  O OH  . TYR A 1 119 ? 12.56084  -29.03165 -2.98742  1.000 102.63962 ? 79  TYR A OH  1 
ATOM   568  N N   . GLU A 1 120 ? 16.03672  -21.91014 0.85450   1.000 63.12421  ? 80  GLU A N   1 
ATOM   569  C CA  . GLU A 1 120 ? 17.02829  -21.01966 1.43942   1.000 58.29151  ? 80  GLU A CA  1 
ATOM   570  C C   . GLU A 1 120 ? 16.81208  -20.78441 2.93026   1.000 56.80666  ? 80  GLU A C   1 
ATOM   571  O O   . GLU A 1 120 ? 17.72444  -20.28627 3.59943   1.000 56.73934  ? 80  GLU A O   1 
ATOM   572  C CB  . GLU A 1 120 ? 16.98774  -19.66525 0.72002   1.000 67.50543  ? 80  GLU A CB  1 
ATOM   573  C CG  . GLU A 1 120 ? 17.35998  -19.69950 -0.75543  1.000 71.82371  ? 80  GLU A CG  1 
ATOM   574  C CD  . GLU A 1 120 ? 18.83378  -19.92517 -0.98749  1.000 75.89825  ? 80  GLU A CD  1 
ATOM   575  O OE1 . GLU A 1 120 ? 19.64063  -19.48604 -0.14249  1.000 92.76129  ? 80  GLU A OE1 1 
ATOM   576  O OE2 . GLU A 1 120 ? 19.18177  -20.54494 -2.01389  1.000 88.64777  ? 80  GLU A OE2 1 
ATOM   577  N N   . THR A 1 121 ? 15.64686  -21.15509 3.46727   1.000 56.14153  ? 81  THR A N   1 
ATOM   578  C CA  . THR A 1 121 ? 15.17907  -20.67645 4.76632   1.000 57.98403  ? 81  THR A CA  1 
ATOM   579  C C   . THR A 1 121 ? 15.82579  -21.34918 5.97949   1.000 49.29332  ? 81  THR A C   1 
ATOM   580  O O   . THR A 1 121 ? 16.22523  -20.64038 6.91279   1.000 57.31777  ? 81  THR A O   1 
ATOM   581  C CB  . THR A 1 121 ? 13.65553  -20.81844 4.84131   1.000 51.13859  ? 81  THR A CB  1 
ATOM   582  O OG1 . THR A 1 121 ? 13.05734  -20.02646 3.81044   1.000 49.40737  ? 81  THR A OG1 1 
ATOM   583  C CG2 . THR A 1 121 ? 13.13570  -20.34488 6.19161   1.000 46.97973  ? 81  THR A CG2 1 
ATOM   584  N N   . PRO A 1 122 ? 15.95045  -22.68542 6.03140   1.000 48.67962  ? 82  PRO A N   1 
ATOM   585  C CA  . PRO A 1 122 ? 16.57033  -23.29367 7.22537   1.000 47.62704  ? 82  PRO A CA  1 
ATOM   586  C C   . PRO A 1 122 ? 17.98143  -22.80630 7.50525   1.000 53.87085  ? 82  PRO A C   1 
ATOM   587  O O   . PRO A 1 122 ? 18.32822  -22.57908 8.67145   1.000 50.73933  ? 82  PRO A O   1 
ATOM   588  C CB  . PRO A 1 122 ? 16.54221  -24.79471 6.90506   1.000 43.77168  ? 82  PRO A CB  1 
ATOM   589  C CG  . PRO A 1 122 ? 15.39655  -24.94939 5.97619   1.000 47.71922  ? 82  PRO A CG  1 
ATOM   590  C CD  . PRO A 1 122 ? 15.43645  -23.72187 5.11597   1.000 51.07839  ? 82  PRO A CD  1 
ATOM   591  N N   . ALA A 1 123 ? 18.81041  -22.64645 6.46980   1.000 53.92884  ? 83  ALA A N   1 
ATOM   592  C CA  . ALA A 1 123 ? 20.17304  -22.16701 6.68280   1.000 50.82985  ? 83  ALA A CA  1 
ATOM   593  C C   . ALA A 1 123 ? 20.17827  -20.73806 7.21170   1.000 51.95406  ? 83  ALA A C   1 
ATOM   594  O O   . ALA A 1 123 ? 20.96181  -20.40223 8.10863   1.000 56.68347  ? 83  ALA A O   1 
ATOM   595  C CB  . ALA A 1 123 ? 20.97338  -22.26583 5.38446   1.000 53.65591  ? 83  ALA A CB  1 
ATOM   596  N N   . ILE A 1 124 ? 19.31673  -19.87985 6.65735   1.000 49.14260  ? 84  ILE A N   1 
ATOM   597  C CA  . ILE A 1 124 ? 19.19346  -18.50992 7.15039   1.000 48.10969  ? 84  ILE A CA  1 
ATOM   598  C C   . ILE A 1 124 ? 18.73535  -18.50488 8.60259   1.000 55.26391  ? 84  ILE A C   1 
ATOM   599  O O   . ILE A 1 124 ? 19.22511  -17.71760 9.42286   1.000 49.43550  ? 84  ILE A O   1 
ATOM   600  C CB  . ILE A 1 124 ? 18.23754  -17.70504 6.25095   1.000 49.84521  ? 84  ILE A CB  1 
ATOM   601  C CG1 . ILE A 1 124 ? 18.81658  -17.58578 4.84105   1.000 51.25724  ? 84  ILE A CG1 1 
ATOM   602  C CG2 . ILE A 1 124 ? 17.97700  -16.32441 6.83840   1.000 32.16481  ? 84  ILE A CG2 1 
ATOM   603  C CD1 . ILE A 1 124 ? 17.89725  -16.89776 3.86478   1.000 41.90024  ? 84  ILE A CD1 1 
ATOM   604  N N   . ALA A 1 125 ? 17.78558  -19.37984 8.94133   1.000 47.05209  ? 85  ALA A N   1 
ATOM   605  C CA  . ALA A 1 125 ? 17.29270  -19.45526 10.31328  1.000 50.30845  ? 85  ALA A CA  1 
ATOM   606  C C   . ALA A 1 125 ? 18.40723  -19.84931 11.27510  1.000 55.03000  ? 85  ALA A C   1 
ATOM   607  O O   . ALA A 1 125 ? 18.60433  -19.20384 12.31152  1.000 52.47005  ? 85  ALA A O   1 
ATOM   608  C CB  . ALA A 1 125 ? 16.12794  -20.44336 10.40153  1.000 48.08097  ? 85  ALA A CB  1 
ATOM   609  N N   . LYS A 1 126 ? 19.13520  -20.92478 10.95301  1.000 52.20200  ? 86  LYS A N   1 
ATOM   610  C CA  . LYS A 1 126 ? 20.24098  -21.36683 11.79960  1.000 56.69363  ? 86  LYS A CA  1 
ATOM   611  C C   . LYS A 1 126 ? 21.25262  -20.25182 12.02861  1.000 56.36483  ? 86  LYS A C   1 
ATOM   612  O O   . LYS A 1 126 ? 21.78362  -20.10188 13.13508  1.000 65.25183  ? 86  LYS A O   1 
ATOM   613  C CB  . LYS A 1 126 ? 20.93560  -22.57200 11.16609  1.000 55.47920  ? 86  LYS A CB  1 
ATOM   614  C CG  . LYS A 1 126 ? 20.11375  -23.83933 11.12807  1.000 53.55476  ? 86  LYS A CG  1 
ATOM   615  C CD  . LYS A 1 126 ? 20.78608  -24.87347 10.24121  1.000 47.39626  ? 86  LYS A CD  1 
ATOM   616  C CE  . LYS A 1 126 ? 19.96062  -26.14076 10.14538  1.000 51.41495  ? 86  LYS A CE  1 
ATOM   617  N NZ  . LYS A 1 126 ? 20.62561  -27.16413 9.29460   1.000 63.12962  ? 86  LYS A NZ  1 
ATOM   618  N N   . GLU A 1 127 ? 21.53991  -19.46721 10.98975  1.000 52.71717  ? 87  GLU A N   1 
ATOM   619  C CA  . GLU A 1 127 ? 22.47552  -18.35773 11.13222  1.000 50.64609  ? 87  GLU A CA  1 
ATOM   620  C C   . GLU A 1 127 ? 21.96878  -17.33290 12.14413  1.000 55.47553  ? 87  GLU A C   1 
ATOM   621  O O   . GLU A 1 127 ? 22.73638  -16.83752 12.97771  1.000 53.58326  ? 87  GLU A O   1 
ATOM   622  C CB  . GLU A 1 127 ? 22.72086  -17.70828 9.77043   1.000 55.20714  ? 87  GLU A CB  1 
ATOM   623  C CG  . GLU A 1 127 ? 23.93279  -16.79700 9.72805   1.000 77.11281  ? 87  GLU A CG  1 
ATOM   624  C CD  . GLU A 1 127 ? 24.36152  -16.46032 8.31344   1.000 98.27274  ? 87  GLU A CD  1 
ATOM   625  O OE1 . GLU A 1 127 ? 24.63672  -17.39114 7.52816   1.000 98.38751  ? 87  GLU A OE1 1 
ATOM   626  O OE2 . GLU A 1 127 ? 24.43017  -15.25632 7.99148   1.000 101.54035 ? 87  GLU A OE2 1 
ATOM   627  N N   . LEU A 1 128 ? 20.67611  -16.99862 12.08552  1.000 54.08426  ? 88  LEU A N   1 
ATOM   628  C CA  . LEU A 1 128 ? 20.13910  -15.94228 12.93942  1.000 48.06117  ? 88  LEU A CA  1 
ATOM   629  C C   . LEU A 1 128 ? 19.87877  -16.44212 14.35519  1.000 50.45311  ? 88  LEU A C   1 
ATOM   630  O O   . LEU A 1 128 ? 20.03401  -15.68536 15.32087  1.000 51.59136  ? 88  LEU A O   1 
ATOM   631  C CB  . LEU A 1 128 ? 18.85886  -15.37599 12.32492  1.000 45.01693  ? 88  LEU A CB  1 
ATOM   632  C CG  . LEU A 1 128 ? 19.08379  -14.48608 11.10288  1.000 46.48669  ? 88  LEU A CG  1 
ATOM   633  C CD1 . LEU A 1 128 ? 17.77839  -14.20889 10.37380  1.000 45.60398  ? 88  LEU A CD1 1 
ATOM   634  C CD2 . LEU A 1 128 ? 19.75058  -13.19292 11.52428  1.000 47.40904  ? 88  LEU A CD2 1 
ATOM   635  N N   . LEU A 1 129 ? 19.46191  -17.70284 14.49540  1.000 50.30516  ? 89  LEU A N   1 
ATOM   636  C CA  . LEU A 1 129 ? 19.34301  -18.29554 15.82289  1.000 51.79828  ? 89  LEU A CA  1 
ATOM   637  C C   . LEU A 1 129 ? 20.67486  -18.25343 16.56140  1.000 58.65796  ? 89  LEU A C   1 
ATOM   638  O O   . LEU A 1 129 ? 20.71681  -17.97880 17.76600  1.000 61.59349  ? 89  LEU A O   1 
ATOM   639  C CB  . LEU A 1 129 ? 18.83196  -19.73177 15.71724  1.000 48.92072  ? 89  LEU A CB  1 
ATOM   640  C CG  . LEU A 1 129 ? 17.37966  -19.91758 15.27818  1.000 47.28620  ? 89  LEU A CG  1 
ATOM   641  C CD1 . LEU A 1 129 ? 17.11013  -21.37454 14.94077  1.000 48.42481  ? 89  LEU A CD1 1 
ATOM   642  C CD2 . LEU A 1 129 ? 16.42801  -19.43249 16.36124  1.000 42.13762  ? 89  LEU A CD2 1 
ATOM   643  N N   . ALA A 1 130 ? 21.77421  -18.53909 15.85597  1.000 55.84191  ? 90  ALA A N   1 
ATOM   644  C CA  . ALA A 1 130 ? 23.08793  -18.55434 16.49180  1.000 55.36526  ? 90  ALA A CA  1 
ATOM   645  C C   . ALA A 1 130 ? 23.47374  -17.17928 17.02051  1.000 56.21847  ? 90  ALA A C   1 
ATOM   646  O O   . ALA A 1 130 ? 24.27402  -17.07575 17.95695  1.000 53.46749  ? 90  ALA A O   1 
ATOM   647  C CB  . ALA A 1 130 ? 24.14056  -19.06459 15.50725  1.000 47.51779  ? 90  ALA A CB  1 
ATOM   648  N N   . ARG A 1 131 ? 22.92353  -16.11629 16.43911  1.000 53.45149  ? 91  ARG A N   1 
ATOM   649  C CA  . ARG A 1 131 ? 23.11219  -14.77359 16.97013  1.000 44.11819  ? 91  ARG A CA  1 
ATOM   650  C C   . ARG A 1 131 ? 22.16611  -14.45828 18.12062  1.000 45.38440  ? 91  ARG A C   1 
ATOM   651  O O   . ARG A 1 131 ? 22.15692  -13.32125 18.60112  1.000 51.70059  ? 91  ARG A O   1 
ATOM   652  C CB  . ARG A 1 131 ? 22.94377  -13.73291 15.86114  1.000 50.81275  ? 91  ARG A CB  1 
ATOM   653  C CG  . ARG A 1 131 ? 23.89874  -13.90920 14.69179  1.000 51.98292  ? 91  ARG A CG  1 
ATOM   654  C CD  . ARG A 1 131 ? 23.95290  -12.64806 13.83438  1.000 74.06102  ? 91  ARG A CD  1 
ATOM   655  N NE  . ARG A 1 131 ? 24.22889  -12.93379 12.43072  1.000 77.92501  ? 91  ARG A NE  1 
ATOM   656  C CZ  . ARG A 1 131 ? 24.41606  -12.00841 11.49853  1.000 75.85749  ? 91  ARG A CZ  1 
ATOM   657  N NH1 . ARG A 1 131 ? 24.38299  -10.71749 11.78816  1.000 76.41377  ? 91  ARG A NH1 1 
ATOM   658  N NH2 . ARG A 1 131 ? 24.64207  -12.38778 10.24385  1.000 66.20673  ? 91  ARG A NH2 1 
ATOM   659  N N   . GLY A 1 132 ? 21.37956  -15.43185 18.57374  1.000 50.57997  ? 92  GLY A N   1 
ATOM   660  C CA  . GLY A 1 132 ? 20.42764  -15.19393 19.63911  1.000 46.86192  ? 92  GLY A CA  1 
ATOM   661  C C   . GLY A 1 132 ? 19.14848  -14.51130 19.21903  1.000 47.36020  ? 92  GLY A C   1 
ATOM   662  O O   . GLY A 1 132 ? 18.41184  -14.02173 20.08008  1.000 49.19345  ? 92  GLY A O   1 
ATOM   663  N N   . ILE A 1 133 ? 18.85410  -14.46942 17.92297  1.000 38.77797  ? 93  ILE A N   1 
ATOM   664  C CA  . ILE A 1 133 ? 17.65990  -13.81606 17.39945  1.000 42.72424  ? 93  ILE A CA  1 
ATOM   665  C C   . ILE A 1 133 ? 16.58320  -14.86507 17.15908  1.000 51.84461  ? 93  ILE A C   1 
ATOM   666  O O   . ILE A 1 133 ? 16.85008  -15.91677 16.56238  1.000 53.90417  ? 93  ILE A O   1 
ATOM   667  C CB  . ILE A 1 133 ? 17.97400  -13.04380 16.10731  1.000 45.89970  ? 93  ILE A CB  1 
ATOM   668  C CG1 . ILE A 1 133 ? 19.09130  -12.02823 16.35654  1.000 50.77609  ? 93  ILE A CG1 1 
ATOM   669  C CG2 . ILE A 1 133 ? 16.72798  -12.34939 15.58462  1.000 45.43215  ? 93  ILE A CG2 1 
ATOM   670  C CD1 . ILE A 1 133 ? 19.56368  -11.31940 15.10880  1.000 42.19727  ? 93  ILE A CD1 1 
ATOM   671  N N   . HIS A 1 134 ? 15.36949  -14.58650 17.62952  1.000 50.43927  ? 94  HIS A N   1 
ATOM   672  C CA  . HIS A 1 134 ? 14.23993  -15.45687 17.33780  1.000 44.36774  ? 94  HIS A CA  1 
ATOM   673  C C   . HIS A 1 134 ? 13.91771  -15.41284 15.84873  1.000 48.18437  ? 94  HIS A C   1 
ATOM   674  O O   . HIS A 1 134 ? 14.10286  -14.39173 15.18114  1.000 49.44771  ? 94  HIS A O   1 
ATOM   675  C CB  . HIS A 1 134 ? 13.01114  -15.03873 18.14735  1.000 47.45481  ? 94  HIS A CB  1 
ATOM   676  C CG  . HIS A 1 134 ? 13.25683  -14.93717 19.62136  1.000 48.33302  ? 94  HIS A CG  1 
ATOM   677  N ND1 . HIS A 1 134 ? 14.08464  -15.80418 20.30193  1.000 51.86801  ? 94  HIS A ND1 1 
ATOM   678  C CD2 . HIS A 1 134 ? 12.78023  -14.06954 20.54553  1.000 46.63286  ? 94  HIS A CD2 1 
ATOM   679  C CE1 . HIS A 1 134 ? 14.10656  -15.47602 21.58145  1.000 51.82933  ? 94  HIS A CE1 1 
ATOM   680  N NE2 . HIS A 1 134 ? 13.32407  -14.42602 21.75555  1.000 57.18183  ? 94  HIS A NE2 1 
ATOM   681  N N   . THR A 1 135 ? 13.43366  -16.53704 15.32378  1.000 48.12078  ? 95  THR A N   1 
ATOM   682  C CA  . THR A 1 135 ? 13.13463  -16.65161 13.90315  1.000 54.89674  ? 95  THR A CA  1 
ATOM   683  C C   . THR A 1 135 ? 11.74465  -17.23473 13.69305  1.000 49.90390  ? 95  THR A C   1 
ATOM   684  O O   . THR A 1 135 ? 11.36079  -18.20992 14.34714  1.000 43.40133  ? 95  THR A O   1 
ATOM   685  C CB  . THR A 1 135 ? 14.17014  -17.52802 13.17784  1.000 54.26239  ? 95  THR A CB  1 
ATOM   686  O OG1 . THR A 1 135 ? 14.13273  -18.85647 13.71209  1.000 54.08910  ? 95  THR A OG1 1 
ATOM   687  C CG2 . THR A 1 135 ? 15.57683  -16.95461 13.33248  1.000 50.87150  ? 95  THR A CG2 1 
ATOM   688  N N   . ILE A 1 136 ? 10.99987  -16.63213 12.76831  1.000 46.90235  ? 96  ILE A N   1 
ATOM   689  C CA  . ILE A 1 136 ? 9.71402   -17.14315 12.31183  1.000 42.74451  ? 96  ILE A CA  1 
ATOM   690  C C   . ILE A 1 136 ? 9.83288   -17.44734 10.82645  1.000 48.85952  ? 96  ILE A C   1 
ATOM   691  O O   . ILE A 1 136 ? 10.40040  -16.65538 10.06602  1.000 54.65045  ? 96  ILE A O   1 
ATOM   692  C CB  . ILE A 1 136 ? 8.56725   -16.14377 12.57177  1.000 45.61396  ? 96  ILE A CB  1 
ATOM   693  C CG1 . ILE A 1 136 ? 8.61401   -15.63673 14.01472  1.000 39.16102  ? 96  ILE A CG1 1 
ATOM   694  C CG2 . ILE A 1 136 ? 7.21699   -16.79128 12.27644  1.000 41.39550  ? 96  ILE A CG2 1 
ATOM   695  C CD1 . ILE A 1 136 ? 8.32291   -16.70275 15.04809  1.000 51.52870  ? 96  ILE A CD1 1 
ATOM   696  N N   . ASP A 1 137 ? 9.30453   -18.59524 10.41366  1.000 45.31625  ? 97  ASP A N   1 
ATOM   697  C CA  . ASP A 1 137 ? 9.28475   -18.95527 9.00543   1.000 48.60017  ? 97  ASP A CA  1 
ATOM   698  C C   . ASP A 1 137 ? 8.00516   -19.71482 8.69576   1.000 48.77386  ? 97  ASP A C   1 
ATOM   699  O O   . ASP A 1 137 ? 7.31083   -20.19764 9.59351   1.000 47.97763  ? 97  ASP A O   1 
ATOM   700  C CB  . ASP A 1 137 ? 10.51477  -19.79306 8.61898   1.000 52.97502  ? 97  ASP A CB  1 
ATOM   701  C CG  . ASP A 1 137 ? 10.52020  -21.16919 9.26723   1.000 59.85999  ? 97  ASP A CG  1 
ATOM   702  O OD1 . ASP A 1 137 ? 9.70978   -22.03236 8.86914   1.000 56.08814  ? 97  ASP A OD1 1 
ATOM   703  O OD2 . ASP A 1 137 ? 11.34306  -21.39251 10.17803  1.000 65.35453  ? 97  ASP A OD2 1 
ATOM   704  N N   . SER A 1 138 ? 7.70193   -19.81222 7.40519   1.000 53.47095  ? 98  SER A N   1 
ATOM   705  C CA  . SER A 1 138 ? 6.56558   -20.57589 6.90739   1.000 53.75241  ? 98  SER A CA  1 
ATOM   706  C C   . SER A 1 138 ? 7.02959   -21.70617 5.99532   1.000 54.47769  ? 98  SER A C   1 
ATOM   707  O O   . SER A 1 138 ? 6.40764   -21.99811 4.97150   1.000 55.66377  ? 98  SER A O   1 
ATOM   708  C CB  . SER A 1 138 ? 5.57053   -19.66738 6.19056   1.000 46.15366  ? 98  SER A CB  1 
ATOM   709  O OG  . SER A 1 138 ? 6.20855   -18.90381 5.18350   1.000 57.27285  ? 98  SER A OG  1 
ATOM   710  N N   . PHE A 1 139 ? 8.15516   -22.32747 6.35402   1.000 57.27764  ? 99  PHE A N   1 
ATOM   711  C CA  . PHE A 1 139 ? 8.67139   -23.49363 5.64282   1.000 51.12411  ? 99  PHE A CA  1 
ATOM   712  C C   . PHE A 1 139 ? 7.55618   -24.49776 5.38035   1.000 55.18567  ? 99  PHE A C   1 
ATOM   713  O O   . PHE A 1 139 ? 6.83083   -24.89027 6.29721   1.000 57.78050  ? 99  PHE A O   1 
ATOM   714  C CB  . PHE A 1 139 ? 9.79578   -24.13099 6.46317   1.000 52.30969  ? 99  PHE A CB  1 
ATOM   715  C CG  . PHE A 1 139 ? 10.50752  -25.25326 5.76480   1.000 54.59573  ? 99  PHE A CG  1 
ATOM   716  C CD1 . PHE A 1 139 ? 11.58102  -24.99829 4.92823   1.000 50.83758  ? 99  PHE A CD1 1 
ATOM   717  C CD2 . PHE A 1 139 ? 10.12343  -26.56644 5.97389   1.000 57.04008  ? 99  PHE A CD2 1 
ATOM   718  C CE1 . PHE A 1 139 ? 12.24454  -26.03229 4.29613   1.000 64.31809  ? 99  PHE A CE1 1 
ATOM   719  C CE2 . PHE A 1 139 ? 10.78226  -27.60452 5.34586   1.000 64.70910  ? 99  PHE A CE2 1 
ATOM   720  C CZ  . PHE A 1 139 ? 11.84401  -27.33795 4.50563   1.000 59.29622  ? 99  PHE A CZ  1 
ATOM   721  N N   . ASP A 1 140 ? 7.41815   -24.91020 4.11735   1.000 52.24314  ? 100 ASP A N   1 
ATOM   722  C CA  . ASP A 1 140 ? 6.21551   -25.60252 3.66434   1.000 56.10660  ? 100 ASP A CA  1 
ATOM   723  C C   . ASP A 1 140 ? 6.49709   -26.95518 3.01622   1.000 62.65878  ? 100 ASP A C   1 
ATOM   724  O O   . ASP A 1 140 ? 5.66095   -27.45080 2.25471   1.000 69.44267  ? 100 ASP A O   1 
ATOM   725  C CB  . ASP A 1 140 ? 5.42288   -24.71232 2.70243   1.000 65.63157  ? 100 ASP A CB  1 
ATOM   726  C CG  . ASP A 1 140 ? 6.25146   -24.23869 1.51833   1.000 64.19045  ? 100 ASP A CG  1 
ATOM   727  O OD1 . ASP A 1 140 ? 7.41173   -24.67663 1.37793   1.000 68.28249  ? 100 ASP A OD1 1 
ATOM   728  O OD2 . ASP A 1 140 ? 5.73919   -23.41764 0.72625   1.000 71.18710  ? 100 ASP A OD2 1 
ATOM   729  N N   . ILE A 1 141 ? 7.64571   -27.56587 3.28969   1.000 58.03845  ? 101 ILE A N   1 
ATOM   730  C CA  . ILE A 1 141 ? 7.93198   -28.92514 2.84230   1.000 61.47994  ? 101 ILE A CA  1 
ATOM   731  C C   . ILE A 1 141 ? 7.55845   -29.84730 3.99801   1.000 62.13264  ? 101 ILE A C   1 
ATOM   732  O O   . ILE A 1 141 ? 8.32241   -30.00713 4.95393   1.000 55.17550  ? 101 ILE A O   1 
ATOM   733  C CB  . ILE A 1 141 ? 9.39061   -29.10001 2.41536   1.000 56.99271  ? 101 ILE A CB  1 
ATOM   734  C CG1 . ILE A 1 141 ? 9.74038   -28.12411 1.29471   1.000 56.94378  ? 101 ILE A CG1 1 
ATOM   735  C CG2 . ILE A 1 141 ? 9.62196   -30.51552 1.93184   1.000 53.66836  ? 101 ILE A CG2 1 
ATOM   736  C CD1 . ILE A 1 141 ? 11.16657  -28.24690 0.80684   1.000 71.55743  ? 101 ILE A CD1 1 
ATOM   737  N N   . HIS A 1 142 ? 6.36532   -30.44426 3.91353   1.000 57.98023  ? 102 HIS A N   1 
ATOM   738  C CA  . HIS A 1 142 ? 5.81985   -31.20654 5.03400   1.000 52.32462  ? 102 HIS A CA  1 
ATOM   739  C C   . HIS A 1 142 ? 6.72939   -32.36059 5.43635   1.000 60.89163  ? 102 HIS A C   1 
ATOM   740  O O   . HIS A 1 142 ? 6.91916   -32.61979 6.63011   1.000 62.72099  ? 102 HIS A O   1 
ATOM   741  C CB  . HIS A 1 142 ? 4.42494   -31.72448 4.68198   1.000 58.61605  ? 102 HIS A CB  1 
ATOM   742  C CG  . HIS A 1 142 ? 3.39674   -30.64606 4.53916   1.000 70.84853  ? 102 HIS A CG  1 
ATOM   743  N ND1 . HIS A 1 142 ? 2.71695   -30.11932 5.61669   1.000 59.07295  ? 102 HIS A ND1 1 
ATOM   744  C CD2 . HIS A 1 142 ? 2.93776   -29.99043 3.44704   1.000 63.59008  ? 102 HIS A CD2 1 
ATOM   745  C CE1 . HIS A 1 142 ? 1.88026   -29.18882 5.19350   1.000 54.73238  ? 102 HIS A CE1 1 
ATOM   746  N NE2 . HIS A 1 142 ? 1.99545   -29.09035 3.88124   1.000 58.98138  ? 102 HIS A NE2 1 
ATOM   747  N N   . GLN A 1 143 ? 7.29931   -33.06762 4.45760   1.000 58.90316  ? 103 GLN A N   1 
ATOM   748  C CA  . GLN A 1 143 ? 8.09682   -34.25017 4.76455   1.000 58.20622  ? 103 GLN A CA  1 
ATOM   749  C C   . GLN A 1 143 ? 9.39841   -33.91061 5.47803   1.000 68.06735  ? 103 GLN A C   1 
ATOM   750  O O   . GLN A 1 143 ? 10.03027  -34.80795 6.04603   1.000 73.96155  ? 103 GLN A O   1 
ATOM   751  C CB  . GLN A 1 143 ? 8.40892   -35.03543 3.48854   1.000 68.63689  ? 103 GLN A CB  1 
ATOM   752  C CG  . GLN A 1 143 ? 7.27898   -35.07079 2.47663   1.000 82.46073  ? 103 GLN A CG  1 
ATOM   753  C CD  . GLN A 1 143 ? 7.41890   -33.99147 1.42327   1.000 91.10126  ? 103 GLN A CD  1 
ATOM   754  O OE1 . GLN A 1 143 ? 8.37113   -33.99238 0.64245   1.000 110.57907 ? 103 GLN A OE1 1 
ATOM   755  N NE2 . GLN A 1 143 ? 6.47588   -33.05792 1.40149   1.000 76.81899  ? 103 GLN A NE2 1 
ATOM   756  N N   . GLU A 1 144 ? 9.81393   -32.64602 5.46239   1.000 61.55595  ? 104 GLU A N   1 
ATOM   757  C CA  . GLU A 1 144 ? 11.08311  -32.23902 6.04423   1.000 61.13764  ? 104 GLU A CA  1 
ATOM   758  C C   . GLU A 1 144 ? 10.91989  -31.48115 7.35516   1.000 58.96089  ? 104 GLU A C   1 
ATOM   759  O O   . GLU A 1 144 ? 11.92290  -31.05001 7.93157   1.000 48.02033  ? 104 GLU A O   1 
ATOM   760  C CB  . GLU A 1 144 ? 11.84641  -31.35784 5.04625   1.000 64.41746  ? 104 GLU A CB  1 
ATOM   761  C CG  . GLU A 1 144 ? 12.28488  -32.05082 3.75548   1.000 66.60017  ? 104 GLU A CG  1 
ATOM   762  C CD  . GLU A 1 144 ? 13.50100  -32.93570 3.91230   1.000 84.69497  ? 104 GLU A CD  1 
ATOM   763  O OE1 . GLU A 1 144 ? 13.51275  -33.79422 4.81870   1.000 93.08883  ? 104 GLU A OE1 1 
ATOM   764  O OE2 . GLU A 1 144 ? 14.44865  -32.77200 3.11609   1.000 95.09590  ? 104 GLU A OE2 1 
ATOM   765  N N   . ILE A 1 145 ? 9.68930   -31.31940 7.84755   1.000 52.62743  ? 105 ILE A N   1 
ATOM   766  C CA  . ILE A 1 145 ? 9.45048   -30.46209 9.00692   1.000 48.66749  ? 105 ILE A CA  1 
ATOM   767  C C   . ILE A 1 145 ? 10.05512  -31.06733 10.26911  1.000 47.36948  ? 105 ILE A C   1 
ATOM   768  O O   . ILE A 1 145 ? 10.72304  -30.37369 11.04569  1.000 52.60665  ? 105 ILE A O   1 
ATOM   769  C CB  . ILE A 1 145 ? 7.94341   -30.19745 9.17378   1.000 52.78588  ? 105 ILE A CB  1 
ATOM   770  C CG1 . ILE A 1 145 ? 7.44688   -29.24192 8.08714   1.000 51.46466  ? 105 ILE A CG1 1 
ATOM   771  C CG2 . ILE A 1 145 ? 7.64629   -29.63965 10.56092  1.000 39.06195  ? 105 ILE A CG2 1 
ATOM   772  C CD1 . ILE A 1 145 ? 5.96835   -28.95536 8.16323   1.000 59.22186  ? 105 ILE A CD1 1 
ATOM   773  N N   . VAL A 1 146 ? 9.81517   -32.36206 10.50209  1.000 50.78106  ? 106 VAL A N   1 
ATOM   774  C CA  . VAL A 1 146 ? 10.36041  -33.02904 11.68589  1.000 49.32974  ? 106 VAL A CA  1 
ATOM   775  C C   . VAL A 1 146 ? 11.87520  -32.86891 11.74268  1.000 56.58754  ? 106 VAL A C   1 
ATOM   776  O O   . VAL A 1 146 ? 12.44576  -32.52979 12.78656  1.000 54.18451  ? 106 VAL A O   1 
ATOM   777  C CB  . VAL A 1 146 ? 9.95080   -34.51264 11.70518  1.000 53.55497  ? 106 VAL A CB  1 
ATOM   778  C CG1 . VAL A 1 146 ? 10.72518  -35.26716 12.77904  1.000 48.98341  ? 106 VAL A CG1 1 
ATOM   779  C CG2 . VAL A 1 146 ? 8.45691   -34.64460 11.93364  1.000 54.97163  ? 106 VAL A CG2 1 
ATOM   780  N N   . GLN A 1 147 ? 12.54970  -33.12573 10.62049  1.000 55.48973  ? 107 GLN A N   1 
ATOM   781  C CA  . GLN A 1 147 ? 14.00577  -33.01860 10.58773  1.000 58.33832  ? 107 GLN A CA  1 
ATOM   782  C C   . GLN A 1 147 ? 14.45776  -31.57696 10.78383  1.000 59.78999  ? 107 GLN A C   1 
ATOM   783  O O   . GLN A 1 147 ? 15.36820  -31.30365 11.57460  1.000 59.94180  ? 107 GLN A O   1 
ATOM   784  C CB  . GLN A 1 147 ? 14.54624  -33.57922 9.27220   1.000 56.19288  ? 107 GLN A CB  1 
ATOM   785  C CG  . GLN A 1 147 ? 16.04405  -33.39442 9.07964   1.000 68.07314  ? 107 GLN A CG  1 
ATOM   786  C CD  . GLN A 1 147 ? 16.86372  -34.13191 10.11768  1.000 71.88237  ? 107 GLN A CD  1 
ATOM   787  O OE1 . GLN A 1 147 ? 16.46770  -35.19215 10.60215  1.000 82.76227  ? 107 GLN A OE1 1 
ATOM   788  N NE2 . GLN A 1 147 ? 18.01956  -33.57621 10.45956  1.000 70.27132  ? 107 GLN A NE2 1 
ATOM   789  N N   . VAL A 1 148 ? 13.84072  -30.64111 10.05955  1.000 50.89988  ? 108 VAL A N   1 
ATOM   790  C CA  . VAL A 1 148 ? 14.20965  -29.23481 10.19274  1.000 54.05377  ? 108 VAL A CA  1 
ATOM   791  C C   . VAL A 1 148 ? 13.93723  -28.74662 11.61057  1.000 58.29114  ? 108 VAL A C   1 
ATOM   792  O O   . VAL A 1 148 ? 14.71402  -27.96422 12.17317  1.000 53.57553  ? 108 VAL A O   1 
ATOM   793  C CB  . VAL A 1 148 ? 13.46834  -28.38712 9.14051   1.000 54.14574  ? 108 VAL A CB  1 
ATOM   794  C CG1 . VAL A 1 148 ? 13.63517  -26.90857 9.42980   1.000 42.52483  ? 108 VAL A CG1 1 
ATOM   795  C CG2 . VAL A 1 148 ? 13.98504  -28.70437 7.74464   1.000 46.13905  ? 108 VAL A CG2 1 
ATOM   796  N N   . ARG A 1 149 ? 12.83906  -29.21075 12.21510  1.000 50.65198  ? 109 ARG A N   1 
ATOM   797  C CA  . ARG A 1 149 ? 12.52338  -28.82749 13.58925  1.000 51.17063  ? 109 ARG A CA  1 
ATOM   798  C C   . ARG A 1 149 ? 13.63685  -29.23710 14.54730  1.000 53.96879  ? 109 ARG A C   1 
ATOM   799  O O   . ARG A 1 149 ? 14.05159  -28.45000 15.40649  1.000 46.66754  ? 109 ARG A O   1 
ATOM   800  C CB  . ARG A 1 149 ? 11.19111  -29.44334 14.01863  1.000 52.19330  ? 109 ARG A CB  1 
ATOM   801  C CG  . ARG A 1 149 ? 10.75119  -29.03838 15.41496  1.000 44.82180  ? 109 ARG A CG  1 
ATOM   802  C CD  . ARG A 1 149 ? 9.52586   -29.81377 15.86673  1.000 54.46714  ? 109 ARG A CD  1 
ATOM   803  N NE  . ARG A 1 149 ? 9.33945   -29.71762 17.30924  1.000 60.38245  ? 109 ARG A NE  1 
ATOM   804  C CZ  . ARG A 1 149 ? 9.94464   -30.49605 18.19587  1.000 58.09599  ? 109 ARG A CZ  1 
ATOM   805  N NH1 . ARG A 1 149 ? 10.79144  -31.44202 17.82225  1.000 64.17682  ? 109 ARG A NH1 1 
ATOM   806  N NH2 . ARG A 1 149 ? 9.70203   -30.31430 19.49061  1.000 58.11444  ? 109 ARG A NH2 1 
ATOM   807  N N   . HIS A 1 150 ? 14.12665  -30.47544 14.42007  1.000 55.15761  ? 110 HIS A N   1 
ATOM   808  C CA  . HIS A 1 150 ? 15.21566  -30.93523 15.27950  1.000 56.47567  ? 110 HIS A CA  1 
ATOM   809  C C   . HIS A 1 150 ? 16.47021  -30.09163 15.09551  1.000 48.96776  ? 110 HIS A C   1 
ATOM   810  O O   . HIS A 1 150 ? 17.13162  -29.73046 16.07577  1.000 54.73212  ? 110 HIS A O   1 
ATOM   811  C CB  . HIS A 1 150 ? 15.53136  -32.40717 15.00565  1.000 43.89433  ? 110 HIS A CB  1 
ATOM   812  C CG  . HIS A 1 150 ? 14.59504  -33.36470 15.67369  1.000 49.91592  ? 110 HIS A CG  1 
ATOM   813  N ND1 . HIS A 1 150 ? 14.23134  -33.24446 16.99760  1.000 51.66438  ? 110 HIS A ND1 1 
ATOM   814  C CD2 . HIS A 1 150 ? 13.96250  -34.46827 15.20810  1.000 50.44453  ? 110 HIS A CD2 1 
ATOM   815  C CE1 . HIS A 1 150 ? 13.40597  -34.22579 17.31579  1.000 57.11701  ? 110 HIS A CE1 1 
ATOM   816  N NE2 . HIS A 1 150 ? 13.22632  -34.98248 16.24788  1.000 56.29420  ? 110 HIS A NE2 1 
ATOM   817  N N   . GLU A 1 151 ? 16.81439  -29.76541 13.84825  1.000 45.38277  ? 111 GLU A N   1 
ATOM   818  C CA  . GLU A 1 151 ? 18.03331  -29.00197 13.60178  1.000 45.28164  ? 111 GLU A CA  1 
ATOM   819  C C   . GLU A 1 151 ? 17.92968  -27.59378 14.17669  1.000 63.86347  ? 111 GLU A C   1 
ATOM   820  O O   . GLU A 1 151 ? 18.88200  -27.09574 14.78804  1.000 59.64313  ? 111 GLU A O   1 
ATOM   821  C CB  . GLU A 1 151 ? 18.32999  -28.95731 12.10263  1.000 46.53947  ? 111 GLU A CB  1 
ATOM   822  C CG  . GLU A 1 151 ? 18.53348  -30.33127 11.47183  1.000 54.63500  ? 111 GLU A CG  1 
ATOM   823  C CD  . GLU A 1 151 ? 18.86933  -30.25583 9.99376   1.000 61.52814  ? 111 GLU A CD  1 
ATOM   824  O OE1 . GLU A 1 151 ? 19.15523  -29.14459 9.50483   1.000 65.93525  ? 111 GLU A OE1 1 
ATOM   825  O OE2 . GLU A 1 151 ? 18.84171  -31.30610 9.31897   1.000 62.63861  ? 111 GLU A OE2 1 
ATOM   826  N N   . LEU A 1 152 ? 16.78055  -26.93652 13.99362  1.000 55.23449  ? 112 LEU A N   1 
ATOM   827  C CA  . LEU A 1 152 ? 16.58277  -25.61515 14.58110  1.000 47.74409  ? 112 LEU A CA  1 
ATOM   828  C C   . LEU A 1 152 ? 16.50046  -25.67698 16.10161  1.000 53.31765  ? 112 LEU A C   1 
ATOM   829  O O   . LEU A 1 152 ? 16.94571  -24.74478 16.78073  1.000 54.04385  ? 112 LEU A O   1 
ATOM   830  C CB  . LEU A 1 152 ? 15.32046  -24.96666 14.01010  1.000 51.67285  ? 112 LEU A CB  1 
ATOM   831  C CG  . LEU A 1 152 ? 15.25742  -24.75485 12.49525  1.000 47.93281  ? 112 LEU A CG  1 
ATOM   832  C CD1 . LEU A 1 152 ? 14.08525  -23.85617 12.13720  1.000 43.99725  ? 112 LEU A CD1 1 
ATOM   833  C CD2 . LEU A 1 152 ? 16.55581  -24.17085 11.97655  1.000 51.13448  ? 112 LEU A CD2 1 
ATOM   834  N N   . ASP A 1 153 ? 15.93388  -26.75570 16.65099  1.000 49.96298  ? 113 ASP A N   1 
ATOM   835  C CA  . ASP A 1 153 ? 15.81637  -26.87669 18.10198  1.000 54.70801  ? 113 ASP A CA  1 
ATOM   836  C C   . ASP A 1 153 ? 17.18507  -26.84744 18.76480  1.000 53.27159  ? 113 ASP A C   1 
ATOM   837  O O   . ASP A 1 153 ? 17.37654  -26.18422 19.79075  1.000 52.93195  ? 113 ASP A O   1 
ATOM   838  C CB  . ASP A 1 153 ? 15.07381  -28.16415 18.46441  1.000 42.87468  ? 113 ASP A CB  1 
ATOM   839  C CG  . ASP A 1 153 ? 14.64843  -28.20591 19.92202  1.000 47.10703  ? 113 ASP A CG  1 
ATOM   840  O OD1 . ASP A 1 153 ? 13.99280  -27.24928 20.38391  1.000 61.17389  ? 113 ASP A OD1 1 
ATOM   841  O OD2 . ASP A 1 153 ? 14.97948  -29.19571 20.60780  1.000 57.55641  ? 113 ASP A OD2 1 
ATOM   842  N N   . GLU A 1 154 ? 18.14460  -27.57422 18.19332  1.000 56.18882  ? 114 GLU A N   1 
ATOM   843  C CA  . GLU A 1 154 ? 19.47198  -27.67738 18.78537  1.000 52.49016  ? 114 GLU A CA  1 
ATOM   844  C C   . GLU A 1 154 ? 20.21294  -26.34520 18.73337  1.000 54.62351  ? 114 GLU A C   1 
ATOM   845  O O   . GLU A 1 154 ? 20.88007  -25.96174 19.70167  1.000 50.58052  ? 114 GLU A O   1 
ATOM   846  C CB  . GLU A 1 154 ? 20.25175  -28.77419 18.06765  1.000 54.69955  ? 114 GLU A CB  1 
ATOM   847  C CG  . GLU A 1 154 ? 21.74102  -28.57841 18.03354  1.000 69.65129  ? 114 GLU A CG  1 
ATOM   848  C CD  . GLU A 1 154 ? 22.40352  -29.57319 17.11662  1.000 78.39497  ? 114 GLU A CD  1 
ATOM   849  O OE1 . GLU A 1 154 ? 21.88156  -29.79801 16.00434  1.000 79.41538  ? 114 GLU A OE1 1 
ATOM   850  O OE2 . GLU A 1 154 ? 23.43314  -30.14429 17.51384  1.000 75.74225  ? 114 GLU A OE2 1 
ATOM   851  N N   . VAL A 1 155 ? 20.10620  -25.62322 17.61575  1.000 53.46126  ? 115 VAL A N   1 
ATOM   852  C CA  . VAL A 1 155 ? 20.74636  -24.31501 17.52120  1.000 43.30437  ? 115 VAL A CA  1 
ATOM   853  C C   . VAL A 1 155 ? 20.06184  -23.31820 18.44797  1.000 53.55613  ? 115 VAL A C   1 
ATOM   854  O O   . VAL A 1 155 ? 20.72567  -22.53183 19.13480  1.000 49.25451  ? 115 VAL A O   1 
ATOM   855  C CB  . VAL A 1 155 ? 20.75226  -23.82402 16.06297  1.000 41.72164  ? 115 VAL A CB  1 
ATOM   856  C CG1 . VAL A 1 155 ? 21.57769  -22.55597 15.93964  1.000 34.85237  ? 115 VAL A CG1 1 
ATOM   857  C CG2 . VAL A 1 155 ? 21.29179  -24.90440 15.14279  1.000 47.58829  ? 115 VAL A CG2 1 
ATOM   858  N N   . ALA A 1 156 ? 18.72559  -23.33422 18.48152  1.000 54.88196  ? 116 ALA A N   1 
ATOM   859  C CA  . ALA A 1 156 ? 17.98719  -22.38249 19.30691  1.000 56.05101  ? 116 ALA A CA  1 
ATOM   860  C C   . ALA A 1 156 ? 18.31624  -22.55845 20.78498  1.000 55.11743  ? 116 ALA A C   1 
ATOM   861  O O   . ALA A 1 156 ? 18.52904  -21.57360 21.50261  1.000 46.99023  ? 116 ALA A O   1 
ATOM   862  C CB  . ALA A 1 156 ? 16.48452  -22.53468 19.06708  1.000 47.52317  ? 116 ALA A CB  1 
ATOM   863  N N   . ARG A 1 157 ? 18.35801  -23.80692 21.25836  1.000 56.22171  ? 117 ARG A N   1 
ATOM   864  C CA  . ARG A 1 157 ? 18.68247  -24.06387 22.65869  1.000 58.32769  ? 117 ARG A CA  1 
ATOM   865  C C   . ARG A 1 157 ? 20.10996  -23.64806 22.98431  1.000 59.63771  ? 117 ARG A C   1 
ATOM   866  O O   . ARG A 1 157 ? 20.38967  -23.18768 24.09706  1.000 66.75558  ? 117 ARG A O   1 
ATOM   867  C CB  . ARG A 1 157 ? 18.47540  -25.54045 22.98685  1.000 50.43360  ? 117 ARG A CB  1 
ATOM   868  C CG  . ARG A 1 157 ? 17.02990  -25.97489 23.00806  1.000 51.63985  ? 117 ARG A CG  1 
ATOM   869  C CD  . ARG A 1 157 ? 16.79472  -26.93936 24.14541  1.000 52.18654  ? 117 ARG A CD  1 
ATOM   870  N NE  . ARG A 1 157 ? 15.93762  -28.04428 23.74007  1.000 81.10877  ? 117 ARG A NE  1 
ATOM   871  C CZ  . ARG A 1 157 ? 15.76784  -29.14928 24.45018  1.000 83.59463  ? 117 ARG A CZ  1 
ATOM   872  N NH1 . ARG A 1 157 ? 16.39144  -29.33008 25.60277  1.000 74.99170  ? 117 ARG A NH1 1 
ATOM   873  N NH2 . ARG A 1 157 ? 14.95452  -30.09646 23.99204  1.000 62.56407  ? 117 ARG A NH2 1 
ATOM   874  N N   . ALA A 1 158 ? 21.02567  -23.80366 22.02815  1.000 52.61766  ? 118 ALA A N   1 
ATOM   875  C CA  . ALA A 1 158 ? 22.41556  -23.44411 22.26650  1.000 49.87163  ? 118 ALA A CA  1 
ATOM   876  C C   . ALA A 1 158 ? 22.60186  -21.94329 22.43633  1.000 56.28107  ? 118 ALA A C   1 
ATOM   877  O O   . ALA A 1 158 ? 23.60594  -21.51953 23.01935  1.000 62.20095  ? 118 ALA A O   1 
ATOM   878  C CB  . ALA A 1 158 ? 23.29234  -23.95236 21.12195  1.000 36.78737  ? 118 ALA A CB  1 
ATOM   879  N N   . HIS A 1 159 ? 21.66421  -21.12977 21.93999  1.000 48.30810  ? 119 HIS A N   1 
ATOM   880  C CA  . HIS A 1 159 ? 21.83061  -19.68146 21.94168  1.000 42.03778  ? 119 HIS A CA  1 
ATOM   881  C C   . HIS A 1 159 ? 20.63151  -18.96728 22.55258  1.000 47.12839  ? 119 HIS A C   1 
ATOM   882  O O   . HIS A 1 159 ? 20.40180  -17.79273 22.24951  1.000 43.27834  ? 119 HIS A O   1 
ATOM   883  C CB  . HIS A 1 159 ? 22.08567  -19.16854 20.52454  1.000 39.17749  ? 119 HIS A CB  1 
ATOM   884  C CG  . HIS A 1 159 ? 23.34350  -19.70008 19.91749  1.000 51.27020  ? 119 HIS A CG  1 
ATOM   885  N ND1 . HIS A 1 159 ? 23.37655  -20.85249 19.16327  1.000 55.44157  ? 119 HIS A ND1 1 
ATOM   886  C CD2 . HIS A 1 159 ? 24.61936  -19.25370 19.97924  1.000 46.03726  ? 119 HIS A CD2 1 
ATOM   887  C CE1 . HIS A 1 159 ? 24.61689  -21.08552 18.77369  1.000 48.24518  ? 119 HIS A CE1 1 
ATOM   888  N NE2 . HIS A 1 159 ? 25.39026  -20.12928 19.25458  1.000 49.67768  ? 119 HIS A NE2 1 
ATOM   889  N N   . GLN A 1 160 ? 19.85796  -19.65724 23.39143  1.000 51.10115  ? 120 GLN A N   1 
ATOM   890  C CA  . GLN A 1 160 ? 18.75704  -19.04273 24.12943  1.000 56.90712  ? 120 GLN A CA  1 
ATOM   891  C C   . GLN A 1 160 ? 17.78815  -18.31942 23.18997  1.000 58.72111  ? 120 GLN A C   1 
ATOM   892  O O   . GLN A 1 160 ? 17.37129  -17.18544 23.43709  1.000 55.58657  ? 120 GLN A O   1 
ATOM   893  C CB  . GLN A 1 160 ? 19.30716  -18.10088 25.20258  1.000 52.14797  ? 120 GLN A CB  1 
ATOM   894  C CG  . GLN A 1 160 ? 18.30177  -17.68667 26.25540  1.000 77.19169  ? 120 GLN A CG  1 
ATOM   895  C CD  . GLN A 1 160 ? 18.78517  -16.52835 27.09393  1.000 93.84702  ? 120 GLN A CD  1 
ATOM   896  O OE1 . GLN A 1 160 ? 19.98384  -16.27007 27.18596  1.000 103.71175 ? 120 GLN A OE1 1 
ATOM   897  N NE2 . GLN A 1 160 ? 17.84979  -15.81510 27.70757  1.000 76.86739  ? 120 GLN A NE2 1 
ATOM   898  N N   . ALA A 1 161 ? 17.43540  -18.97672 22.08745  1.000 49.13361  ? 121 ALA A N   1 
ATOM   899  C CA  . ALA A 1 161 ? 16.55994  -18.39813 21.07826  1.000 57.82153  ? 121 ALA A CA  1 
ATOM   900  C C   . ALA A 1 161 ? 15.36392  -19.30950 20.82936  1.000 51.38058  ? 121 ALA A C   1 
ATOM   901  O O   . ALA A 1 161 ? 15.37001  -20.49281 21.17856  1.000 55.27317  ? 121 ALA A O   1 
ATOM   902  C CB  . ALA A 1 161 ? 17.31024  -18.14316 19.76234  1.000 45.72601  ? 121 ALA A CB  1 
ATOM   903  N N   . VAL A 1 162 ? 14.32255  -18.73869 20.23214  1.000 43.93357  ? 122 VAL A N   1 
ATOM   904  C CA  . VAL A 1 162 ? 13.09542  -19.46064 19.92550  1.000 45.92299  ? 122 VAL A CA  1 
ATOM   905  C C   . VAL A 1 162 ? 12.89077  -19.42733 18.42111  1.000 48.03985  ? 122 VAL A C   1 
ATOM   906  O O   . VAL A 1 162 ? 12.90261  -18.35165 17.81178  1.000 51.81419  ? 122 VAL A O   1 
ATOM   907  C CB  . VAL A 1 162 ? 11.87546  -18.85669 20.64595  1.000 45.74390  ? 122 VAL A CB  1 
ATOM   908  C CG1 . VAL A 1 162 ? 10.60114  -19.58039 20.21829  1.000 52.14960  ? 122 VAL A CG1 1 
ATOM   909  C CG2 . VAL A 1 162 ? 12.05368  -18.91996 22.15335  1.000 48.12134  ? 122 VAL A CG2 1 
ATOM   910  N N   . ALA A 1 163 ? 12.69692  -20.59985 17.82771  1.000 48.27549  ? 123 ALA A N   1 
ATOM   911  C CA  . ALA A 1 163 ? 12.37437  -20.71912 16.41550  1.000 50.73727  ? 123 ALA A CA  1 
ATOM   912  C C   . ALA A 1 163 ? 10.98003  -21.30930 16.28821  1.000 56.22671  ? 123 ALA A C   1 
ATOM   913  O O   . ALA A 1 163 ? 10.69419  -22.36712 16.85766  1.000 48.18361  ? 123 ALA A O   1 
ATOM   914  C CB  . ALA A 1 163 ? 13.39222  -21.59430 15.68248  1.000 37.05039  ? 123 ALA A CB  1 
ATOM   915  N N   . ILE A 1 164 ? 10.11227  -20.62352 15.55526  1.000 46.64967  ? 124 ILE A N   1 
ATOM   916  C CA  . ILE A 1 164 ? 8.80939   -21.15856 15.18825  1.000 45.19880  ? 124 ILE A CA  1 
ATOM   917  C C   . ILE A 1 164 ? 8.81576   -21.35109 13.68049  1.000 50.56990  ? 124 ILE A C   1 
ATOM   918  O O   . ILE A 1 164 ? 8.95623   -20.38348 12.92144  1.000 56.80616  ? 124 ILE A O   1 
ATOM   919  C CB  . ILE A 1 164 ? 7.66665   -20.23851 15.63956  1.000 51.60620  ? 124 ILE A CB  1 
ATOM   920  C CG1 . ILE A 1 164 ? 7.65495   -20.11337 17.16531  1.000 45.26423  ? 124 ILE A CG1 1 
ATOM   921  C CG2 . ILE A 1 164 ? 6.33081   -20.77157 15.15163  1.000 46.77794  ? 124 ILE A CG2 1 
ATOM   922  C CD1 . ILE A 1 164 ? 6.77916   -18.99122 17.67045  1.000 56.73013  ? 124 ILE A CD1 1 
ATOM   923  N N   . LEU A 1 165 ? 8.66290   -22.59706 13.24963  1.000 47.68002  ? 125 LEU A N   1 
ATOM   924  C CA  . LEU A 1 165 ? 8.76293   -22.96452 11.84872  1.000 53.88191  ? 125 LEU A CA  1 
ATOM   925  C C   . LEU A 1 165 ? 7.41930   -23.47121 11.34671  1.000 53.31040  ? 125 LEU A C   1 
ATOM   926  O O   . LEU A 1 165 ? 6.55564   -23.88086 12.12770  1.000 53.27843  ? 125 LEU A O   1 
ATOM   927  C CB  . LEU A 1 165 ? 9.84874   -24.02944 11.63637  1.000 43.04481  ? 125 LEU A CB  1 
ATOM   928  C CG  . LEU A 1 165 ? 9.55524   -25.45466 12.11703  1.000 54.84172  ? 125 LEU A CG  1 
ATOM   929  C CD1 . LEU A 1 165 ? 10.41423  -26.45058 11.35667  1.000 47.09766  ? 125 LEU A CD1 1 
ATOM   930  C CD2 . LEU A 1 165 ? 9.78225   -25.60092 13.62055  1.000 52.70567  ? 125 LEU A CD2 1 
ATOM   931  N N   . ALA A 1 166 ? 7.25181   -23.42222 10.02364  1.000 50.64491  ? 126 ALA A N   1 
ATOM   932  C CA  . ALA A 1 166 ? 6.03654   -23.89125 9.35989   1.000 54.87393  ? 126 ALA A CA  1 
ATOM   933  C C   . ALA A 1 166 ? 4.80525   -23.13273 9.84568   1.000 56.45938  ? 126 ALA A C   1 
ATOM   934  O O   . ALA A 1 166 ? 3.70850   -23.69128 9.92550   1.000 52.08294  ? 126 ALA A O   1 
ATOM   935  C CB  . ALA A 1 166 ? 5.84646   -25.40054 9.54245   1.000 56.09049  ? 126 ALA A CB  1 
ATOM   936  N N   . ALA A 1 167 ? 4.97741   -21.85317 10.16295  1.000 57.57999  ? 127 ALA A N   1 
ATOM   937  C CA  . ALA A 1 167 ? 3.92671   -21.03975 10.76349  1.000 55.68665  ? 127 ALA A CA  1 
ATOM   938  C C   . ALA A 1 167 ? 3.34667   -20.11052 9.70237   1.000 57.36591  ? 127 ALA A C   1 
ATOM   939  O O   . ALA A 1 167 ? 3.54060   -18.89308 9.72423   1.000 55.34419  ? 127 ALA A O   1 
ATOM   940  C CB  . ALA A 1 167 ? 4.47521   -20.26064 11.96082  1.000 50.12175  ? 127 ALA A CB  1 
ATOM   941  N N   . GLY A 1 168 ? 2.61761   -20.70845 8.76550   1.000 49.91133  ? 128 GLY A N   1 
ATOM   942  C CA  . GLY A 1 168 ? 1.96637   -19.98472 7.69026   1.000 53.59408  ? 128 GLY A CA  1 
ATOM   943  C C   . GLY A 1 168 ? 0.49382   -20.33958 7.60720   1.000 62.24850  ? 128 GLY A C   1 
ATOM   944  O O   . GLY A 1 168 ? -0.20529  -20.46873 8.61631   1.000 51.06462  ? 128 GLY A O   1 
ATOM   945  N N   . LEU A 1 169 ? 0.01886   -20.47230 6.36866   1.000 59.05077  ? 129 LEU A N   1 
ATOM   946  C CA  . LEU A 1 169 ? -1.36090  -20.87244 6.12836   1.000 49.37873  ? 129 LEU A CA  1 
ATOM   947  C C   . LEU A 1 169 ? -1.50141  -22.38943 6.15645   1.000 55.52847  ? 129 LEU A C   1 
ATOM   948  O O   . LEU A 1 169 ? -2.32272  -22.93181 6.90429   1.000 51.09993  ? 129 LEU A O   1 
ATOM   949  C CB  . LEU A 1 169 ? -1.83322  -20.30180 4.78825   1.000 54.04187  ? 129 LEU A CB  1 
ATOM   950  C CG  . LEU A 1 169 ? -3.02628  -20.96213 4.09874   1.000 63.51849  ? 129 LEU A CG  1 
ATOM   951  C CD1 . LEU A 1 169 ? -4.26208  -20.83156 4.95389   1.000 65.08727  ? 129 LEU A CD1 1 
ATOM   952  C CD2 . LEU A 1 169 ? -3.25415  -20.35397 2.72233   1.000 66.18278  ? 129 LEU A CD2 1 
ATOM   953  N N   . LEU A 1 170 ? -0.70635  -23.08519 5.34914   1.000 56.29481  ? 130 LEU A N   1 
ATOM   954  C CA  . LEU A 1 170 ? -0.67517  -24.54730 5.34515   1.000 58.81920  ? 130 LEU A CA  1 
ATOM   955  C C   . LEU A 1 170 ? 0.70968   -24.96653 4.87654   1.000 60.93011  ? 130 LEU A C   1 
ATOM   956  O O   . LEU A 1 170 ? 1.01652   -24.89206 3.67669   1.000 69.02470  ? 130 LEU A O   1 
ATOM   957  C CB  . LEU A 1 170 ? -1.76107  -25.14396 4.45437   1.000 63.87930  ? 130 LEU A CB  1 
ATOM   958  C CG  . LEU A 1 170 ? -1.77816  -26.67088 4.36032   1.000 55.26296  ? 130 LEU A CG  1 
ATOM   959  C CD1 . LEU A 1 170 ? -1.88738  -27.28741 5.74425   1.000 53.77535  ? 130 LEU A CD1 1 
ATOM   960  C CD2 . LEU A 1 170 ? -2.90741  -27.15109 3.45973   1.000 45.13552  ? 130 LEU A CD2 1 
ATOM   961  N N   . PRO A 1 171 ? 1.58209   -25.41487 5.79179   1.000 59.13349  ? 131 PRO A N   1 
ATOM   962  C CA  . PRO A 1 171 ? 1.37048   -25.63841 7.23217   1.000 54.98489  ? 131 PRO A CA  1 
ATOM   963  C C   . PRO A 1 171 ? 1.20882   -24.35139 8.03524   1.000 50.75716  ? 131 PRO A C   1 
ATOM   964  O O   . PRO A 1 171 ? 1.53401   -23.26514 7.56518   1.000 59.62375  ? 131 PRO A O   1 
ATOM   965  C CB  . PRO A 1 171 ? 2.63585   -26.40286 7.64058   1.000 51.21291  ? 131 PRO A CB  1 
ATOM   966  C CG  . PRO A 1 171 ? 3.68707   -25.86536 6.72195   1.000 53.67278  ? 131 PRO A CG  1 
ATOM   967  C CD  . PRO A 1 171 ? 2.98035   -25.67848 5.40470   1.000 56.65484  ? 131 PRO A CD  1 
ATOM   968  N N   . GLY A 1 172 ? 0.70168   -24.45892 9.26002   1.000 54.42945  ? 132 GLY A N   1 
ATOM   969  C CA  . GLY A 1 172 ? 0.40928   -23.29415 10.06990  1.000 44.94908  ? 132 GLY A CA  1 
ATOM   970  C C   . GLY A 1 172 ? -0.94645  -23.37787 10.74081  1.000 51.97950  ? 132 GLY A C   1 
ATOM   971  O O   . GLY A 1 172 ? -1.22173  -24.33508 11.47072  1.000 52.44355  ? 132 GLY A O   1 
ATOM   972  N N   . THR A 1 173 ? -1.80462  -22.38137 10.50511  1.000 45.71047  ? 133 THR A N   1 
ATOM   973  C CA  . THR A 1 173 ? -3.09385  -22.34560 11.18966  1.000 49.74631  ? 133 THR A CA  1 
ATOM   974  C C   . THR A 1 173 ? -4.00305  -23.49064 10.75492  1.000 53.96274  ? 133 THR A C   1 
ATOM   975  O O   . THR A 1 173 ? -4.77819  -24.00497 11.56978  1.000 37.95467  ? 133 THR A O   1 
ATOM   976  C CB  . THR A 1 173 ? -3.78476  -21.00325 10.94692  1.000 47.67058  ? 133 THR A CB  1 
ATOM   977  O OG1 . THR A 1 173 ? -3.80852  -20.72639 9.54111   1.000 54.02577  ? 133 THR A OG1 1 
ATOM   978  C CG2 . THR A 1 173 ? -3.05299  -19.88055 11.67232  1.000 49.43681  ? 133 THR A CG2 1 
ATOM   979  N N   . CYS A 1 174 ? -3.92416  -23.90669 9.48670   1.000 48.36118  ? 134 CYS A N   1 
ATOM   980  C CA  . CYS A 1 174 ? -4.69707  -25.06476 9.04811   1.000 44.68562  ? 134 CYS A CA  1 
ATOM   981  C C   . CYS A 1 174 ? -4.24830  -26.32573 9.76835   1.000 55.54138  ? 134 CYS A C   1 
ATOM   982  O O   . CYS A 1 174 ? -5.06894  -27.20443 10.05638  1.000 53.32697  ? 134 CYS A O   1 
ATOM   983  C CB  . CYS A 1 174 ? -4.57206  -25.25429 7.53631   1.000 55.49626  ? 134 CYS A CB  1 
ATOM   984  S SG  . CYS A 1 174 ? -5.49116  -24.05919 6.54586   1.000 62.53325  ? 134 CYS A SG  1 
ATOM   985  N N   . SER A 1 175 ? -2.94939  -26.43531 10.05666  1.000 51.24697  ? 135 SER A N   1 
ATOM   986  C CA  . SER A 1 175 ? -2.45620  -27.55544 10.84732  1.000 44.55813  ? 135 SER A CA  1 
ATOM   987  C C   . SER A 1 175 ? -3.05966  -27.54073 12.24419  1.000 47.76017  ? 135 SER A C   1 
ATOM   988  O O   . SER A 1 175 ? -3.38215  -28.59638 12.80130  1.000 48.55695  ? 135 SER A O   1 
ATOM   989  C CB  . SER A 1 175 ? -0.93071  -27.51436 10.91193  1.000 52.88922  ? 135 SER A CB  1 
ATOM   990  O OG  . SER A 1 175 ? -0.37566  -27.30979 9.62511   1.000 57.61730  ? 135 SER A OG  1 
ATOM   991  N N   . MET A 1 176 ? -3.20586  -26.35151 12.83189  1.000 39.78441  ? 136 MET A N   1 
ATOM   992  C CA  . MET A 1 176 ? -3.79028  -26.25125 14.16399  1.000 41.92632  ? 136 MET A CA  1 
ATOM   993  C C   . MET A 1 176 ? -5.24042  -26.72168 14.15929  1.000 51.84769  ? 136 MET A C   1 
ATOM   994  O O   . MET A 1 176 ? -5.65229  -27.51064 15.01770  1.000 46.32114  ? 136 MET A O   1 
ATOM   995  C CB  . MET A 1 176 ? -3.68617  -24.81310 14.67042  1.000 52.19473  ? 136 MET A CB  1 
ATOM   996  C CG  . MET A 1 176 ? -2.29387  -24.21677 14.55454  1.000 54.88087  ? 136 MET A CG  1 
ATOM   997  S SD  . MET A 1 176 ? -2.24350  -22.48562 15.06163  1.000 55.62716  ? 136 MET A SD  1 
ATOM   998  C CE  . MET A 1 176 ? -2.82467  -22.60187 16.74850  1.000 35.25347  ? 136 MET A CE  1 
ATOM   999  N N   . ILE A 1 177 ? -6.03167  -26.23613 13.19776  1.000 48.02067  ? 137 ILE A N   1 
ATOM   1000 C CA  . ILE A 1 177 ? -7.41895  -26.67659 13.06178  1.000 49.22521  ? 137 ILE A CA  1 
ATOM   1001 C C   . ILE A 1 177 ? -7.47202  -28.18435 12.84534  1.000 50.71553  ? 137 ILE A C   1 
ATOM   1002 O O   . ILE A 1 177 ? -8.23641  -28.90092 13.50289  1.000 49.83343  ? 137 ILE A O   1 
ATOM   1003 C CB  . ILE A 1 177 ? -8.10964  -25.92157 11.90888  1.000 59.47713  ? 137 ILE A CB  1 
ATOM   1004 C CG1 . ILE A 1 177 ? -7.94362  -24.40555 12.05870  1.000 43.94140  ? 137 ILE A CG1 1 
ATOM   1005 C CG2 . ILE A 1 177 ? -9.58672  -26.29129 11.82844  1.000 51.86213  ? 137 ILE A CG2 1 
ATOM   1006 C CD1 . ILE A 1 177 ? -8.62828  -23.81722 13.25459  1.000 51.13706  ? 137 ILE A CD1 1 
ATOM   1007 N N   . ARG A 1 178 ? -6.65649  -28.68109 11.90997  1.000 50.10438  ? 138 ARG A N   1 
ATOM   1008 C CA  . ARG A 1 178 ? -6.58713  -30.11176 11.62262  1.000 50.52239  ? 138 ARG A CA  1 
ATOM   1009 C C   . ARG A 1 178 ? -6.32273  -30.92984 12.87996  1.000 57.58868  ? 138 ARG A C   1 
ATOM   1010 O O   . ARG A 1 178 ? -6.95265  -31.97182 13.09958  1.000 52.46741  ? 138 ARG A O   1 
ATOM   1011 C CB  . ARG A 1 178 ? -5.50014  -30.36161 10.57544  1.000 58.57255  ? 138 ARG A CB  1 
ATOM   1012 C CG  . ARG A 1 178 ? -5.60886  -31.67189 9.82250   1.000 64.42943  ? 138 ARG A CG  1 
ATOM   1013 C CD  . ARG A 1 178 ? -5.03644  -31.50579 8.42459   1.000 68.32012  ? 138 ARG A CD  1 
ATOM   1014 N NE  . ARG A 1 178 ? -3.65561  -31.04124 8.47563   1.000 51.18535  ? 138 ARG A NE  1 
ATOM   1015 C CZ  . ARG A 1 178 ? -2.91936  -30.74356 7.41384   1.000 59.96765  ? 138 ARG A CZ  1 
ATOM   1016 N NH1 . ARG A 1 178 ? -3.40930  -30.82306 6.18736   1.000 61.52566  ? 138 ARG A NH1 1 
ATOM   1017 N NH2 . ARG A 1 178 ? -1.65974  -30.35297 7.58762   1.000 61.03954  ? 138 ARG A NH2 1 
ATOM   1018 N N   . SER A 1 179 ? -5.39422  -30.47115 13.72030  1.000 49.62754  ? 139 SER A N   1 
ATOM   1019 C CA  . SER A 1 179 ? -5.05929  -31.22049 14.92503  1.000 60.40024  ? 139 SER A CA  1 
ATOM   1020 C C   . SER A 1 179 ? -6.19298  -31.18112 15.93954  1.000 51.06579  ? 139 SER A C   1 
ATOM   1021 O O   . SER A 1 179 ? -6.40375  -32.15569 16.66977  1.000 51.36358  ? 139 SER A O   1 
ATOM   1022 C CB  . SER A 1 179 ? -3.77208  -30.67329 15.54092  1.000 52.48748  ? 139 SER A CB  1 
ATOM   1023 O OG  . SER A 1 179 ? -2.71690  -30.67824 14.59579  1.000 50.90011  ? 139 SER A OG  1 
ATOM   1024 N N   . ILE A 1 180 ? -6.91954  -30.06448 16.00839  1.000 47.36391  ? 140 ILE A N   1 
ATOM   1025 C CA  . ILE A 1 180 ? -8.05208  -29.96736 16.92324  1.000 45.45908  ? 140 ILE A CA  1 
ATOM   1026 C C   . ILE A 1 180 ? -9.16149  -30.92475 16.50347  1.000 53.79640  ? 140 ILE A C   1 
ATOM   1027 O O   . ILE A 1 180 ? -9.78546  -31.58170 17.34650  1.000 53.47135  ? 140 ILE A O   1 
ATOM   1028 C CB  . ILE A 1 180 ? -8.54898  -28.51245 17.00730  1.000 51.79257  ? 140 ILE A CB  1 
ATOM   1029 C CG1 . ILE A 1 180 ? -7.49382  -27.62514 17.67341  1.000 50.14644  ? 140 ILE A CG1 1 
ATOM   1030 C CG2 . ILE A 1 180 ? -9.85453  -28.43777 17.77469  1.000 50.09005  ? 140 ILE A CG2 1 
ATOM   1031 C CD1 . ILE A 1 180 ? -7.80253  -26.14304 17.59052  1.000 48.27325  ? 140 ILE A CD1 1 
ATOM   1032 N N   . LEU A 1 181 ? -9.42669  -31.01925 15.19802  1.000 45.45753  ? 141 LEU A N   1 
ATOM   1033 C CA  . LEU A 1 181 ? -10.37491 -32.01369 14.70597  1.000 47.55053  ? 141 LEU A CA  1 
ATOM   1034 C C   . LEU A 1 181 ? -9.95132  -33.42181 15.10444  1.000 52.73689  ? 141 LEU A C   1 
ATOM   1035 O O   . LEU A 1 181 ? -10.79946 -34.27655 15.38723  1.000 54.95374  ? 141 LEU A O   1 
ATOM   1036 C CB  . LEU A 1 181 ? -10.50344 -31.91841 13.18584  1.000 48.56358  ? 141 LEU A CB  1 
ATOM   1037 C CG  . LEU A 1 181 ? -10.85954 -30.56659 12.56908  1.000 57.70901  ? 141 LEU A CG  1 
ATOM   1038 C CD1 . LEU A 1 181 ? -11.01843 -30.69644 11.05960  1.000 40.96511  ? 141 LEU A CD1 1 
ATOM   1039 C CD2 . LEU A 1 181 ? -12.11676 -29.99740 13.19788  1.000 44.56278  ? 141 LEU A CD2 1 
ATOM   1040 N N   . GLU A 1 182 ? -8.64182  -33.68869 15.10114  1.000 46.70377  ? 142 GLU A N   1 
ATOM   1041 C CA  . GLU A 1 182 ? -8.15210  -35.04027 15.35970  1.000 59.00843  ? 142 GLU A CA  1 
ATOM   1042 C C   . GLU A 1 182 ? -8.55691  -35.52973 16.74447  1.000 57.21314  ? 142 GLU A C   1 
ATOM   1043 O O   . GLU A 1 182 ? -9.02882  -36.66059 16.89583  1.000 52.77044  ? 142 GLU A O   1 
ATOM   1044 C CB  . GLU A 1 182 ? -6.63291  -35.09638 15.19296  1.000 59.25476  ? 142 GLU A CB  1 
ATOM   1045 C CG  . GLU A 1 182 ? -6.16708  -35.32000 13.76559  1.000 63.96907  ? 142 GLU A CG  1 
ATOM   1046 C CD  . GLU A 1 182 ? -6.10632  -36.78684 13.38430  1.000 57.54816  ? 142 GLU A CD  1 
ATOM   1047 O OE1 . GLU A 1 182 ? -5.92694  -37.62426 14.29242  1.000 58.73005  ? 142 GLU A OE1 1 
ATOM   1048 O OE2 . GLU A 1 182 ? -6.23374  -37.09747 12.18139  1.000 65.04763  ? 142 GLU A OE2 1 
ATOM   1049 N N   . PHE A 1 183 ? -8.38668  -34.69816 17.77218  1.000 47.52159  ? 143 PHE A N   1 
ATOM   1050 C CA  . PHE A 1 183 ? -8.69308  -35.16873 19.11677  1.000 50.33102  ? 143 PHE A CA  1 
ATOM   1051 C C   . PHE A 1 183 ? -10.16378 -35.01304 19.48495  1.000 50.93910  ? 143 PHE A C   1 
ATOM   1052 O O   . PHE A 1 183 ? -10.59976 -35.61741 20.47004  1.000 54.14223  ? 143 PHE A O   1 
ATOM   1053 C CB  . PHE A 1 183 ? -7.77571  -34.49601 20.16019  1.000 45.04790  ? 143 PHE A CB  1 
ATOM   1054 C CG  . PHE A 1 183 ? -8.08539  -33.04543 20.45595  1.000 48.14482  ? 143 PHE A CG  1 
ATOM   1055 C CD1 . PHE A 1 183 ? -9.14175  -32.68693 21.28343  1.000 46.78383  ? 143 PHE A CD1 1 
ATOM   1056 C CD2 . PHE A 1 183 ? -7.27544  -32.04332 19.94996  1.000 45.14992  ? 143 PHE A CD2 1 
ATOM   1057 C CE1 . PHE A 1 183 ? -9.40253  -31.35684 21.56655  1.000 52.92845  ? 143 PHE A CE1 1 
ATOM   1058 C CE2 . PHE A 1 183 ? -7.52846  -30.71231 20.23361  1.000 50.10497  ? 143 PHE A CE2 1 
ATOM   1059 C CZ  . PHE A 1 183 ? -8.59312  -30.36838 21.03944  1.000 48.73024  ? 143 PHE A CZ  1 
ATOM   1060 N N   . MET A 1 184 ? -10.93812 -34.21879 18.73671  1.000 49.22796  ? 144 MET A N   1 
ATOM   1061 C CA  . MET A 1 184 ? -12.38690 -34.24328 18.92741  1.000 49.25757  ? 144 MET A CA  1 
ATOM   1062 C C   . MET A 1 184 ? -13.00322 -35.52613 18.38402  1.000 51.82755  ? 144 MET A C   1 
ATOM   1063 O O   . MET A 1 184 ? -14.04987 -35.96551 18.87275  1.000 46.55287  ? 144 MET A O   1 
ATOM   1064 C CB  . MET A 1 184 ? -13.05274 -33.02996 18.27581  1.000 46.49927  ? 144 MET A CB  1 
ATOM   1065 C CG  . MET A 1 184 ? -12.79226 -31.71216 18.97944  1.000 42.46628  ? 144 MET A CG  1 
ATOM   1066 S SD  . MET A 1 184 ? -13.73181 -30.34772 18.26462  1.000 55.48561  ? 144 MET A SD  1 
ATOM   1067 C CE  . MET A 1 184 ? -13.15502 -30.37693 16.57445  1.000 48.30362  ? 144 MET A CE  1 
ATOM   1068 N N   . ALA A 1 185 ? -12.37773 -36.13392 17.37608  1.000 56.31531  ? 145 ALA A N   1 
ATOM   1069 C CA  . ALA A 1 185 ? -12.87871 -37.37422 16.78492  1.000 48.08174  ? 145 ALA A CA  1 
ATOM   1070 C C   . ALA A 1 185 ? -11.69004 -38.21867 16.35620  1.000 50.78109  ? 145 ALA A C   1 
ATOM   1071 O O   . ALA A 1 185 ? -11.25316 -38.16527 15.19817  1.000 55.11355  ? 145 ALA A O   1 
ATOM   1072 C CB  . ALA A 1 185 ? -13.81007 -37.10613 15.60362  1.000 50.13374  ? 145 ALA A CB  1 
ATOM   1073 N N   . PRO A 1 186 ? -11.13680 -39.02198 17.27111  1.000 52.53851  ? 146 PRO A N   1 
ATOM   1074 C CA  . PRO A 1 186 ? -9.87464  -39.72145 16.96940  1.000 47.82396  ? 146 PRO A CA  1 
ATOM   1075 C C   . PRO A 1 186 ? -9.96052  -40.71201 15.81897  1.000 46.82624  ? 146 PRO A C   1 
ATOM   1076 O O   . PRO A 1 186 ? -8.97693  -40.87404 15.08581  1.000 57.86884  ? 146 PRO A O   1 
ATOM   1077 C CB  . PRO A 1 186 ? -9.54727  -40.42726 18.29269  1.000 34.14835  ? 146 PRO A CB  1 
ATOM   1078 C CG  . PRO A 1 186 ? -10.25634 -39.63303 19.33545  1.000 40.76490  ? 146 PRO A CG  1 
ATOM   1079 C CD  . PRO A 1 186 ? -11.52136 -39.15872 18.68636  1.000 40.70755  ? 146 PRO A CD  1 
ATOM   1080 N N   . TYR A 1 187 ? -11.09501 -41.37570 15.62839  1.000 45.69174  ? 147 TYR A N   1 
ATOM   1081 C CA  . TYR A 1 187 ? -11.26326 -42.32860 14.53919  1.000 48.25621  ? 147 TYR A CA  1 
ATOM   1082 C C   . TYR A 1 187 ? -11.94158 -41.62824 13.37142  1.000 48.63371  ? 147 TYR A C   1 
ATOM   1083 O O   . TYR A 1 187 ? -12.94383 -40.93660 13.56245  1.000 56.13800  ? 147 TYR A O   1 
ATOM   1084 C CB  . TYR A 1 187 ? -12.09991 -43.53206 14.98073  1.000 46.90419  ? 147 TYR A CB  1 
ATOM   1085 C CG  . TYR A 1 187 ? -11.55043 -44.27672 16.17493  1.000 49.67732  ? 147 TYR A CG  1 
ATOM   1086 C CD1 . TYR A 1 187 ? -10.20697 -44.62050 16.24970  1.000 65.50963  ? 147 TYR A CD1 1 
ATOM   1087 C CD2 . TYR A 1 187 ? -12.37892 -44.64028 17.22780  1.000 49.55346  ? 147 TYR A CD2 1 
ATOM   1088 C CE1 . TYR A 1 187 ? -9.70469  -45.30358 17.34470  1.000 61.39457  ? 147 TYR A CE1 1 
ATOM   1089 C CE2 . TYR A 1 187 ? -11.88779 -45.32185 18.32509  1.000 67.09870  ? 147 TYR A CE2 1 
ATOM   1090 C CZ  . TYR A 1 187 ? -10.55079 -45.65099 18.37947  1.000 65.43789  ? 147 TYR A CZ  1 
ATOM   1091 O OH  . TYR A 1 187 ? -10.06202 -46.33026 19.47190  1.000 64.12610  ? 147 TYR A OH  1 
ATOM   1092 N N   . GLY A 1 188 ? -11.40104 -41.80422 12.17529  1.000 48.64155  ? 148 GLY A N   1 
ATOM   1093 C CA  . GLY A 1 188 ? -11.96680 -41.20414 10.98974  1.000 40.63378  ? 148 GLY A CA  1 
ATOM   1094 C C   . GLY A 1 188 ? -10.88273 -40.65547 10.09024  1.000 48.97046  ? 148 GLY A C   1 
ATOM   1095 O O   . GLY A 1 188 ? -9.70052  -40.95640 10.24926  1.000 56.88439  ? 148 GLY A O   1 
ATOM   1096 N N   . ILE A 1 189 ? -11.30305 -39.83289 9.12948   1.000 38.07183  ? 149 ILE A N   1 
ATOM   1097 C CA  . ILE A 1 189 ? -10.42757 -39.30551 8.09036   1.000 39.36761  ? 149 ILE A CA  1 
ATOM   1098 C C   . ILE A 1 189 ? -10.67344 -37.81015 7.95071   1.000 48.80404  ? 149 ILE A C   1 
ATOM   1099 O O   . ILE A 1 189 ? -11.81802 -37.34839 8.02134   1.000 50.32193  ? 149 ILE A O   1 
ATOM   1100 C CB  . ILE A 1 189 ? -10.65301 -40.01643 6.73785   1.000 42.73286  ? 149 ILE A CB  1 
ATOM   1101 C CG1 . ILE A 1 189 ? -10.33192 -41.50419 6.85624   1.000 52.88026  ? 149 ILE A CG1 1 
ATOM   1102 C CG2 . ILE A 1 189 ? -9.79910  -39.38953 5.64609   1.000 44.35262  ? 149 ILE A CG2 1 
ATOM   1103 C CD1 . ILE A 1 189 ? -10.52080 -42.26501 5.57388   1.000 48.59593  ? 149 ILE A CD1 1 
ATOM   1104 N N   . THR A 1 190 ? -9.59798  -37.05250 7.76229   1.000 50.71075  ? 150 THR A N   1 
ATOM   1105 C CA  . THR A 1 190 ? -9.68317  -35.63293 7.45620   1.000 50.42863  ? 150 THR A CA  1 
ATOM   1106 C C   . THR A 1 190 ? -9.19610  -35.39924 6.03345   1.000 49.87295  ? 150 THR A C   1 
ATOM   1107 O O   . THR A 1 190 ? -8.13897  -35.90572 5.64293   1.000 58.16729  ? 150 THR A O   1 
ATOM   1108 C CB  . THR A 1 190 ? -8.85902  -34.79897 8.44002   1.000 45.63206  ? 150 THR A CB  1 
ATOM   1109 O OG1 . THR A 1 190 ? -9.38915  -34.94348 9.76210   1.000 48.91280  ? 150 THR A OG1 1 
ATOM   1110 C CG2 . THR A 1 190 ? -8.89835  -33.33082 8.04924   1.000 46.25119  ? 150 THR A CG2 1 
ATOM   1111 N N   . TYR A 1 191 ? -9.96815  -34.63948 5.26485   1.000 52.07849  ? 151 TYR A N   1 
ATOM   1112 C CA  . TYR A 1 191 ? -9.59525  -34.24892 3.91447   1.000 51.33701  ? 151 TYR A CA  1 
ATOM   1113 C C   . TYR A 1 191 ? -9.26539  -32.76563 3.91348   1.000 54.35117  ? 151 TYR A C   1 
ATOM   1114 O O   . TYR A 1 191 ? -10.07210 -31.94807 4.36605   1.000 55.84262  ? 151 TYR A O   1 
ATOM   1115 C CB  . TYR A 1 191 ? -10.72342 -34.54459 2.92412   1.000 53.86312  ? 151 TYR A CB  1 
ATOM   1116 C CG  . TYR A 1 191 ? -11.02932 -36.01601 2.77287   1.000 66.83591  ? 151 TYR A CG  1 
ATOM   1117 C CD1 . TYR A 1 191 ? -10.02211 -36.92603 2.48273   1.000 62.44084  ? 151 TYR A CD1 1 
ATOM   1118 C CD2 . TYR A 1 191 ? -12.32160 -36.49857 2.93178   1.000 56.75069  ? 151 TYR A CD2 1 
ATOM   1119 C CE1 . TYR A 1 191 ? -10.29314 -38.27239 2.34390   1.000 62.21855  ? 151 TYR A CE1 1 
ATOM   1120 C CE2 . TYR A 1 191 ? -12.60279 -37.84698 2.79810   1.000 67.59850  ? 151 TYR A CE2 1 
ATOM   1121 C CZ  . TYR A 1 191 ? -11.58407 -38.72925 2.50482   1.000 70.21216  ? 151 TYR A CZ  1 
ATOM   1122 O OH  . TYR A 1 191 ? -11.86146 -40.07092 2.37116   1.000 75.02753  ? 151 TYR A OH  1 
ATOM   1123 N N   . THR A 1 192 ? -8.08533  -32.42261 3.41019   1.000 51.70925  ? 152 THR A N   1 
ATOM   1124 C CA  . THR A 1 192 ? -7.66591  -31.03420 3.26157   1.000 53.52843  ? 152 THR A CA  1 
ATOM   1125 C C   . THR A 1 192 ? -7.66058  -30.70849 1.77469   1.000 47.96986  ? 152 THR A C   1 
ATOM   1126 O O   . THR A 1 192 ? -6.85404  -31.25543 1.01503   1.000 54.24032  ? 152 THR A O   1 
ATOM   1127 C CB  . THR A 1 192 ? -6.29112  -30.79725 3.88174   1.000 54.27736  ? 152 THR A CB  1 
ATOM   1128 O OG1 . THR A 1 192 ? -6.31280  -31.17553 5.26419   1.000 60.23030  ? 152 THR A OG1 1 
ATOM   1129 C CG2 . THR A 1 192 ? -5.91077  -29.33235 3.77178   1.000 54.27551  ? 152 THR A CG2 1 
ATOM   1130 N N   . ASN A 1 193 ? -8.55959  -29.82258 1.36373   1.000 48.24466  ? 153 ASN A N   1 
ATOM   1131 C CA  . ASN A 1 193 ? -8.76326  -29.49628 -0.04137  1.000 49.46354  ? 153 ASN A CA  1 
ATOM   1132 C C   . ASN A 1 193 ? -8.27556  -28.07121 -0.25789  1.000 54.04723  ? 153 ASN A C   1 
ATOM   1133 O O   . ASN A 1 193 ? -8.92307  -27.11434 0.18055   1.000 66.17518  ? 153 ASN A O   1 
ATOM   1134 C CB  . ASN A 1 193 ? -10.23322 -29.64413 -0.42434  1.000 40.17292  ? 153 ASN A CB  1 
ATOM   1135 C CG  . ASN A 1 193 ? -10.79563 -31.00557 -0.05807  1.000 55.96709  ? 153 ASN A CG  1 
ATOM   1136 O OD1 . ASN A 1 193 ? -10.48407 -32.01199 -0.69355  1.000 56.59039  ? 153 ASN A OD1 1 
ATOM   1137 N ND2 . ASN A 1 193 ? -11.61745 -31.04408 0.98601   1.000 46.58073  ? 153 ASN A ND2 1 
ATOM   1138 N N   . VAL A 1 194 ? -7.14372  -27.93268 -0.94329  1.000 53.58424  ? 154 VAL A N   1 
ATOM   1139 C CA  . VAL A 1 194 ? -6.51612  -26.63570 -1.16454  1.000 56.72585  ? 154 VAL A CA  1 
ATOM   1140 C C   . VAL A 1 194 ? -7.15991  -26.05267 -2.41726  1.000 61.44498  ? 154 VAL A C   1 
ATOM   1141 O O   . VAL A 1 194 ? -6.82406  -26.43291 -3.53845  1.000 48.61341  ? 154 VAL A O   1 
ATOM   1142 C CB  . VAL A 1 194 ? -4.99811  -26.75412 -1.30331  1.000 49.56527  ? 154 VAL A CB  1 
ATOM   1143 C CG1 . VAL A 1 194 ? -4.37801  -25.38006 -1.49732  1.000 44.99652  ? 154 VAL A CG1 1 
ATOM   1144 C CG2 . VAL A 1 194 ? -4.40806  -27.44779 -0.08392  1.000 49.00395  ? 154 VAL A CG2 1 
ATOM   1145 N N   . GLY A 1 195 ? -8.09286  -25.12081 -2.21262  1.000 83.27745  ? 155 GLY A N   1 
ATOM   1146 C CA  . GLY A 1 195 ? -8.91828  -24.56359 -3.26155  1.000 61.14438  ? 155 GLY A CA  1 
ATOM   1147 C C   . GLY A 1 195 ? -8.11764  -23.89473 -4.36020  1.000 60.27664  ? 155 GLY A C   1 
ATOM   1148 O O   . GLY A 1 195 ? -6.88961  -23.77188 -4.27442  1.000 61.76553  ? 155 GLY A O   1 
ATOM   1149 N N   . PRO A 1 196 ? -8.80465  -23.47661 -5.44604  1.000 59.54675  ? 156 PRO A N   1 
ATOM   1150 C CA  . PRO A 1 196 ? -8.09977  -22.87000 -6.58570  1.000 52.85865  ? 156 PRO A CA  1 
ATOM   1151 C C   . PRO A 1 196 ? -7.20683  -21.71737 -6.16306  1.000 44.86863  ? 156 PRO A C   1 
ATOM   1152 O O   . PRO A 1 196 ? -7.67731  -20.71917 -5.60623  1.000 53.47530  ? 156 PRO A O   1 
ATOM   1153 C CB  . PRO A 1 196 ? -9.23989  -22.39034 -7.49229  1.000 47.80835  ? 156 PRO A CB  1 
ATOM   1154 C CG  . PRO A 1 196 ? -10.38583 -23.27497 -7.14258  1.000 57.00002  ? 156 PRO A CG  1 
ATOM   1155 C CD  . PRO A 1 196 ? -10.25722 -23.54806 -5.67218  1.000 49.05386  ? 156 PRO A CD  1 
ATOM   1156 N N   . GLY A 1 197 ? -5.91373  -21.85937 -6.42396  1.000 49.36465  ? 157 GLY A N   1 
ATOM   1157 C CA  . GLY A 1 197 ? -4.95083  -20.85395 -6.03238  1.000 49.06494  ? 157 GLY A CA  1 
ATOM   1158 C C   . GLY A 1 197 ? -3.62276  -21.12257 -6.69511  1.000 52.36265  ? 157 GLY A C   1 
ATOM   1159 O O   . GLY A 1 197 ? -3.38193  -22.20689 -7.23869  1.000 58.40887  ? 157 GLY A O   1 
ATOM   1160 N N   . MET A 1 198 ? -2.76479  -20.11331 -6.64747  1.000 60.29613  ? 158 MET A N   1 
ATOM   1161 C CA  . MET A 1 198 ? -1.47263  -20.19555 -7.30002  1.000 62.88895  ? 158 MET A CA  1 
ATOM   1162 C C   . MET A 1 198 ? -0.51330  -21.03607 -6.47062  1.000 59.46126  ? 158 MET A C   1 
ATOM   1163 O O   . MET A 1 198 ? -0.51961  -20.98196 -5.23643  1.000 63.23143  ? 158 MET A O   1 
ATOM   1164 C CB  . MET A 1 198 ? -0.91039  -18.79040 -7.49947  1.000 64.90277  ? 158 MET A CB  1 
ATOM   1165 C CG  . MET A 1 198 ? 0.42238   -18.72448 -8.20025  1.000 73.96527  ? 158 MET A CG  1 
ATOM   1166 S SD  . MET A 1 198 ? 0.98866   -17.01933 -8.29705  1.000 77.27167  ? 158 MET A SD  1 
ATOM   1167 C CE  . MET A 1 198 ? -0.56052  -16.14866 -8.09156  1.000 57.47558  ? 158 MET A CE  1 
ATOM   1168 N N   . SER A 1 199 ? 0.31177   -21.81914 -7.15699  1.000 67.85693  ? 159 SER A N   1 
ATOM   1169 C CA  . SER A 1 199 ? 1.42605   -22.51614 -6.53131  1.000 77.35735  ? 159 SER A CA  1 
ATOM   1170 C C   . SER A 1 199 ? 2.68964   -21.89904 -7.10963  1.000 81.54501  ? 159 SER A C   1 
ATOM   1171 O O   . SER A 1 199 ? 2.98795   -22.08003 -8.29466  1.000 82.13174  ? 159 SER A O   1 
ATOM   1172 C CB  . SER A 1 199 ? 1.36026   -24.01544 -6.81024  1.000 69.99074  ? 159 SER A CB  1 
ATOM   1173 O OG  . SER A 1 199 ? 2.50770   -24.68445 -6.31732  1.000 88.80338  ? 159 SER A OG  1 
ATOM   1174 N N   . MET A 1 200 ? 3.43496   -21.17647 -6.27383  1.000 69.72401  ? 160 MET A N   1 
ATOM   1175 C CA  . MET A 1 200 ? 4.61897   -20.48911 -6.76721  1.000 80.75708  ? 160 MET A CA  1 
ATOM   1176 C C   . MET A 1 200 ? 5.84633   -21.38620 -6.83461  1.000 91.28695  ? 160 MET A C   1 
ATOM   1177 O O   . MET A 1 200 ? 6.83513   -21.00316 -7.46823  1.000 96.83013  ? 160 MET A O   1 
ATOM   1178 C CB  . MET A 1 200 ? 4.91287   -19.27043 -5.89169  1.000 84.34793  ? 160 MET A CB  1 
ATOM   1179 C CG  . MET A 1 200 ? 5.37378   -18.05545 -6.66693  1.000 89.00550  ? 160 MET A CG  1 
ATOM   1180 S SD  . MET A 1 200 ? 5.53598   -16.60039 -5.61324  1.000 109.67464 ? 160 MET A SD  1 
ATOM   1181 C CE  . MET A 1 200 ? 5.65789   -15.30132 -6.84140  1.000 92.68769  ? 160 MET A CE  1 
ATOM   1182 N N   . SER A 1 201 ? 5.81157   -22.56643 -6.20767  1.000 87.27183  ? 161 SER A N   1 
ATOM   1183 C CA  . SER A 1 201 ? 6.88725   -23.52778 -6.41551  1.000 82.33558  ? 161 SER A CA  1 
ATOM   1184 C C   . SER A 1 201 ? 6.66753   -24.34659 -7.67637  1.000 90.51766  ? 161 SER A C   1 
ATOM   1185 O O   . SER A 1 201 ? 7.63309   -24.83064 -8.27571  1.000 93.07425  ? 161 SER A O   1 
ATOM   1186 C CB  . SER A 1 201 ? 7.01527   -24.45038 -5.20159  1.000 72.54172  ? 161 SER A CB  1 
ATOM   1187 O OG  . SER A 1 201 ? 5.80554   -25.15234 -4.96740  1.000 91.24752  ? 161 SER A OG  1 
ATOM   1188 N N   . ALA A 1 202 ? 5.41146   -24.50820 -8.08999  1.000 89.01641  ? 162 ALA A N   1 
ATOM   1189 C CA  . ALA A 1 202 ? 5.11891   -25.16713 -9.35363  1.000 85.58876  ? 162 ALA A CA  1 
ATOM   1190 C C   . ALA A 1 202 ? 5.21118   -24.20416 -10.52745 1.000 88.29887  ? 162 ALA A C   1 
ATOM   1191 O O   . ALA A 1 202 ? 5.55809   -24.62076 -11.63591 1.000 89.62676  ? 162 ALA A O   1 
ATOM   1192 C CB  . ALA A 1 202 ? 3.73000   -25.80572 -9.30451  1.000 71.78361  ? 162 ALA A CB  1 
ATOM   1193 N N   . SER A 1 203 ? 4.92643   -22.91823 -10.29962 1.000 82.31963  ? 163 SER A N   1 
ATOM   1194 C CA  . SER A 1 203 ? 5.02575   -21.93299 -11.37219 1.000 84.51990  ? 163 SER A CA  1 
ATOM   1195 C C   . SER A 1 203 ? 6.47105   -21.71631 -11.79868 1.000 91.77607  ? 163 SER A C   1 
ATOM   1196 O O   . SER A 1 203 ? 6.76134   -21.61679 -12.99695 1.000 96.04678  ? 163 SER A O   1 
ATOM   1197 C CB  . SER A 1 203 ? 4.39298   -20.61240 -10.93382 1.000 81.44661  ? 163 SER A CB  1 
ATOM   1198 O OG  . SER A 1 203 ? 2.99333   -20.74902 -10.75764 1.000 70.86671  ? 163 SER A OG  1 
ATOM   1199 N N   . VAL A 1 204 ? 7.39447   -21.63784 -10.83696 1.000 88.11068  ? 164 VAL A N   1 
ATOM   1200 C CA  . VAL A 1 204 ? 8.79252   -21.44944 -11.20095 1.000 93.44050  ? 164 VAL A CA  1 
ATOM   1201 C C   . VAL A 1 204 ? 9.39393   -22.73842 -11.73580 1.000 86.60730  ? 164 VAL A C   1 
ATOM   1202 O O   . VAL A 1 204 ? 10.38568  -22.69676 -12.47258 1.000 95.54415  ? 164 VAL A O   1 
ATOM   1203 C CB  . VAL A 1 204 ? 9.61333   -20.91510 -10.01140 1.000 100.06204 ? 164 VAL A CB  1 
ATOM   1204 C CG1 . VAL A 1 204 ? 9.00223   -19.62210 -9.48028  1.000 82.75794  ? 164 VAL A CG1 1 
ATOM   1205 C CG2 . VAL A 1 204 ? 9.71445   -21.96734 -8.91390  1.000 93.97436  ? 164 VAL A CG2 1 
ATOM   1206 N N   . ALA A 1 205 ? 8.81339   -23.88953 -11.39063 1.000 83.02805  ? 165 ALA A N   1 
ATOM   1207 C CA  . ALA A 1 205 ? 9.28491   -25.14322 -11.96411 1.000 85.65477  ? 165 ALA A CA  1 
ATOM   1208 C C   . ALA A 1 205 ? 8.89531   -25.24555 -13.43214 1.000 90.95150  ? 165 ALA A C   1 
ATOM   1209 O O   . ALA A 1 205 ? 9.65897   -25.77325 -14.24783 1.000 97.57398  ? 165 ALA A O   1 
ATOM   1210 C CB  . ALA A 1 205 ? 8.72971   -26.32707 -11.17248 1.000 91.57301  ? 165 ALA A CB  1 
ATOM   1211 N N   . VAL A 1 206 ? 7.70599   -24.74956 -13.78572 1.000 94.10305  ? 166 VAL A N   1 
ATOM   1212 C CA  . VAL A 1 206 ? 7.30245   -24.69635 -15.18499 1.000 94.17381  ? 166 VAL A CA  1 
ATOM   1213 C C   . VAL A 1 206 ? 8.06355   -23.61455 -15.93636 1.000 94.86651  ? 166 VAL A C   1 
ATOM   1214 O O   . VAL A 1 206 ? 8.16557   -23.66981 -17.16566 1.000 92.05435  ? 166 VAL A O   1 
ATOM   1215 C CB  . VAL A 1 206 ? 5.77989   -24.49880 -15.30487 1.000 88.34497  ? 166 VAL A CB  1 
ATOM   1216 C CG1 . VAL A 1 206 ? 5.34329   -24.60759 -16.74873 1.000 91.28551  ? 166 VAL A CG1 1 
ATOM   1217 C CG2 . VAL A 1 206 ? 5.05607   -25.54824 -14.49058 1.000 88.70987  ? 166 VAL A CG2 1 
ATOM   1218 N N   . LYS A 1 207 ? 8.66742   -22.66449 -15.22673 1.000 84.96091  ? 167 LYS A N   1 
ATOM   1219 C CA  . LYS A 1 207 ? 9.37879   -21.59590 -15.91364 1.000 93.94109  ? 167 LYS A CA  1 
ATOM   1220 C C   . LYS A 1 207 ? 10.76735  -22.05432 -16.32803 1.000 101.10412 ? 167 LYS A C   1 
ATOM   1221 O O   . LYS A 1 207 ? 11.29796  -21.57916 -17.33828 1.000 99.46843  ? 167 LYS A O   1 
ATOM   1222 C CB  . LYS A 1 207 ? 9.48463   -20.35210 -15.02630 1.000 90.01436  ? 167 LYS A CB  1 
ATOM   1223 C CG  . LYS A 1 207 ? 8.23619   -19.47705 -14.99110 1.000 97.77021  ? 167 LYS A CG  1 
ATOM   1224 C CD  . LYS A 1 207 ? 8.27357   -18.52733 -13.79853 1.000 100.21028 ? 167 LYS A CD  1 
ATOM   1225 C CE  . LYS A 1 207 ? 6.87521   -18.20617 -13.28003 1.000 96.35752  ? 167 LYS A CE  1 
ATOM   1226 N NZ  . LYS A 1 207 ? 6.79707   -16.83504 -12.68881 1.000 92.01503  ? 167 LYS A NZ  1 
ATOM   1227 N N   . ALA A 1 208 ? 11.35785  -22.97779 -15.57180 1.000 103.55851 ? 168 ALA A N   1 
ATOM   1228 C CA  . ALA A 1 208 ? 12.68947  -23.49448 -15.85086 1.000 97.08346  ? 168 ALA A CA  1 
ATOM   1229 C C   . ALA A 1 208 ? 12.72364  -24.45643 -17.03644 1.000 97.88226  ? 168 ALA A C   1 
ATOM   1230 O O   . ALA A 1 208 ? 13.81482  -24.88782 -17.42782 1.000 112.54361 ? 168 ALA A O   1 
ATOM   1231 C CB  . ALA A 1 208 ? 13.23799  -24.18868 -14.59747 1.000 90.18196  ? 168 ALA A CB  1 
ATOM   1232 N N   . ILE A 1 209 ? 11.56214  -24.80199 -17.61293 1.000 102.23270 ? 169 ILE A N   1 
ATOM   1233 C CA  . ILE A 1 209 ? 11.45443  -25.79099 -18.68118 1.000 107.13191 ? 169 ILE A CA  1 
ATOM   1234 C C   . ILE A 1 209 ? 11.78272  -25.15239 -20.02777 1.000 111.12093 ? 169 ILE A C   1 
ATOM   1235 O O   . ILE A 1 209 ? 11.59618  -23.95105 -20.23823 1.000 105.64377 ? 169 ILE A O   1 
ATOM   1236 C CB  . ILE A 1 209 ? 10.06960  -26.46533 -18.69091 1.000 105.47935 ? 169 ILE A CB  1 
ATOM   1237 C CG1 . ILE A 1 209 ? 9.70064   -26.87982 -17.26468 1.000 107.43682 ? 169 ILE A CG1 1 
ATOM   1238 C CG2 . ILE A 1 209 ? 10.09639  -27.70490 -19.58250 1.000 97.47107  ? 169 ILE A CG2 1 
ATOM   1239 C CD1 . ILE A 1 209 ? 8.65507   -27.97940 -17.21093 1.000 111.72506 ? 169 ILE A CD1 1 
ATOM   1240 N N   . GLU A 1 210 ? 12.37113  -25.93764 -20.92146 1.000 116.42322 ? 170 GLU A N   1 
ATOM   1241 C CA  . GLU A 1 210 ? 12.73816  -25.43380 -22.23951 1.000 115.27388 ? 170 GLU A CA  1 
ATOM   1242 C C   . GLU A 1 210 ? 11.49181  -25.02238 -23.02630 1.000 104.87936 ? 170 GLU A C   1 
ATOM   1243 O O   . GLU A 1 210 ? 10.60133  -25.84631 -23.26818 1.000 101.62688 ? 170 GLU A O   1 
ATOM   1244 C CB  . GLU A 1 210 ? 13.52000  -26.51173 -22.98773 1.000 105.31227 ? 170 GLU A CB  1 
ATOM   1245 C CG  . GLU A 1 210 ? 14.17500  -26.07486 -24.28394 1.000 101.38468 ? 170 GLU A CG  1 
ATOM   1246 C CD  . GLU A 1 210 ? 15.63194  -26.41089 -24.31223 1.000 108.57088 ? 170 GLU A CD  1 
ATOM   1247 O OE1 . GLU A 1 210 ? 16.39087  -25.69398 -23.63636 1.000 107.33200 ? 170 GLU A OE1 1 
ATOM   1248 O OE2 . GLU A 1 210 ? 16.02306  -27.38039 -24.99993 1.000 115.90014 ? 170 GLU A OE2 1 
ATOM   1249 N N   . GLY A 1 211 ? 11.42243  -23.75229 -23.43358 1.000 94.68928  ? 171 GLY A N   1 
ATOM   1250 C CA  . GLY A 1 211 ? 10.36763  -23.30976 -24.32448 1.000 93.00776  ? 171 GLY A CA  1 
ATOM   1251 C C   . GLY A 1 211 ? 9.31697   -22.40591 -23.71657 1.000 103.51180 ? 171 GLY A C   1 
ATOM   1252 O O   . GLY A 1 211 ? 8.48264   -21.88236 -24.46353 1.000 105.99596 ? 171 GLY A O   1 
ATOM   1253 N N   . VAL A 1 212 ? 9.31931   -22.20408 -22.40149 1.000 99.54515  ? 172 VAL A N   1 
ATOM   1254 C CA  . VAL A 1 212 ? 8.31180   -21.40655 -21.70474 1.000 105.14290 ? 172 VAL A CA  1 
ATOM   1255 C C   . VAL A 1 212 ? 8.92961   -20.09023 -21.24273 1.000 89.27739  ? 172 VAL A C   1 
ATOM   1256 O O   . VAL A 1 212 ? 9.89924   -20.07649 -20.47164 1.000 80.18902  ? 172 VAL A O   1 
ATOM   1257 C CB  . VAL A 1 212 ? 7.69846   -22.19196 -20.53343 1.000 102.91418 ? 172 VAL A CB  1 
ATOM   1258 C CG1 . VAL A 1 212 ? 8.59185   -23.35447 -20.17652 1.000 98.46181  ? 172 VAL A CG1 1 
ATOM   1259 C CG2 . VAL A 1 212 ? 7.44083   -21.29680 -19.31875 1.000 93.16756  ? 172 VAL A CG2 1 
ATOM   1260 N N   . LYS A 1 213 ? 8.40485   -18.98683 -21.78521 1.000 89.13743  ? 173 LYS A N   1 
ATOM   1261 C CA  . LYS A 1 213 ? 8.83889   -17.65188 -21.38340 1.000 86.04535  ? 173 LYS A CA  1 
ATOM   1262 C C   . LYS A 1 213 ? 8.30779   -17.28706 -20.00097 1.000 85.41013  ? 173 LYS A C   1 
ATOM   1263 O O   . LYS A 1 213 ? 9.05304   -16.78017 -19.15335 1.000 86.75642  ? 173 LYS A O   1 
ATOM   1264 C CB  . LYS A 1 213 ? 8.37679   -16.63321 -22.42794 1.000 82.73406  ? 173 LYS A CB  1 
ATOM   1265 C CG  . LYS A 1 213 ? 8.71127   -15.18791 -22.11234 1.000 88.20944  ? 173 LYS A CG  1 
ATOM   1266 C CD  . LYS A 1 213 ? 7.45044   -14.42973 -21.71544 1.000 90.67828  ? 173 LYS A CD  1 
ATOM   1267 C CE  . LYS A 1 213 ? 7.75071   -12.98476 -21.35308 1.000 89.65776  ? 173 LYS A CE  1 
ATOM   1268 N NZ  . LYS A 1 213 ? 6.54208   -12.26126 -20.86074 1.000 74.00833  ? 173 LYS A NZ  1 
ATOM   1269 N N   . ASP A 1 214 ? 7.02184   -17.53353 -19.75521 1.000 86.17869  ? 174 ASP A N   1 
ATOM   1270 C CA  . ASP A 1 214 ? 6.46062   -17.39537 -18.41860 1.000 81.84318  ? 174 ASP A CA  1 
ATOM   1271 C C   . ASP A 1 214 ? 5.39917   -18.46796 -18.22001 1.000 76.04695  ? 174 ASP A C   1 
ATOM   1272 O O   . ASP A 1 214 ? 4.90172   -19.05945 -19.18224 1.000 77.17028  ? 174 ASP A O   1 
ATOM   1273 C CB  . ASP A 1 214 ? 5.87715   -15.99542 -18.18789 1.000 76.09217  ? 174 ASP A CB  1 
ATOM   1274 C CG  . ASP A 1 214 ? 5.83846   -15.61600 -16.71627 1.000 73.83379  ? 174 ASP A CG  1 
ATOM   1275 O OD1 . ASP A 1 214 ? 6.10167   -16.49357 -15.86896 1.000 71.18636  ? 174 ASP A OD1 1 
ATOM   1276 O OD2 . ASP A 1 214 ? 5.55023   -14.43899 -16.40740 1.000 79.14349  ? 174 ASP A OD2 1 
ATOM   1277 N N   . ALA A 1 215 ? 5.05346   -18.71487 -16.95608 1.000 73.04970  ? 175 ALA A N   1 
ATOM   1278 C CA  . ALA A 1 215 ? 4.08913   -19.75873 -16.64217 1.000 72.61123  ? 175 ALA A CA  1 
ATOM   1279 C C   . ALA A 1 215 ? 3.36856   -19.45204 -15.33774 1.000 66.68137  ? 175 ALA A C   1 
ATOM   1280 O O   . ALA A 1 215 ? 3.93843   -18.86132 -14.41639 1.000 56.40927  ? 175 ALA A O   1 
ATOM   1281 C CB  . ALA A 1 215 ? 4.76614   -21.12930 -16.55186 1.000 82.64889  ? 175 ALA A CB  1 
ATOM   1282 N N   . LEU A 1 216 ? 2.10468   -19.87099 -15.27388 1.000 65.91014  ? 176 LEU A N   1 
ATOM   1283 C CA  . LEU A 1 216 ? 1.30675   -19.82648 -14.05364 1.000 62.09922  ? 176 LEU A CA  1 
ATOM   1284 C C   . LEU A 1 216 ? 0.75320   -21.21888 -13.79254 1.000 64.24103  ? 176 LEU A C   1 
ATOM   1285 O O   . LEU A 1 216 ? 0.06066   -21.78275 -14.64640 1.000 58.39024  ? 176 LEU A O   1 
ATOM   1286 C CB  . LEU A 1 216 ? 0.16688   -18.80937 -14.16614 1.000 53.37935  ? 176 LEU A CB  1 
ATOM   1287 C CG  . LEU A 1 216 ? -0.83163  -18.80969 -13.00650 1.000 50.73868  ? 176 LEU A CG  1 
ATOM   1288 C CD1 . LEU A 1 216 ? -0.12835  -18.47688 -11.70571 1.000 52.03561  ? 176 LEU A CD1 1 
ATOM   1289 C CD2 . LEU A 1 216 ? -1.97278  -17.83956 -13.26407 1.000 48.60044  ? 176 LEU A CD2 1 
ATOM   1290 N N   . ALA A 1 217 ? 1.05319   -21.76824 -12.61937 1.000 61.29656  ? 177 ALA A N   1 
ATOM   1291 C CA  . ALA A 1 217 ? 0.58822   -23.09012 -12.22168 1.000 60.31884  ? 177 ALA A CA  1 
ATOM   1292 C C   . ALA A 1 217 ? -0.39863  -22.95672 -11.07096 1.000 57.07659  ? 177 ALA A C   1 
ATOM   1293 O O   . ALA A 1 217 ? -0.11686  -22.27157 -10.08166 1.000 57.46156  ? 177 ALA A O   1 
ATOM   1294 C CB  . ALA A 1 217 ? 1.75931   -23.98689 -11.81585 1.000 68.29076  ? 177 ALA A CB  1 
ATOM   1295 N N   . LEU A 1 218 ? -1.54890  -23.60987 -11.20232 1.000 53.40111  ? 178 LEU A N   1 
ATOM   1296 C CA  . LEU A 1 218 ? -2.60491  -23.55683 -10.20231 1.000 55.74777  ? 178 LEU A CA  1 
ATOM   1297 C C   . LEU A 1 218 ? -2.80466  -24.92307 -9.56250  1.000 62.80824  ? 178 LEU A C   1 
ATOM   1298 O O   . LEU A 1 218 ? -2.75449  -25.95254 -10.24391 1.000 59.53287  ? 178 LEU A O   1 
ATOM   1299 C CB  . LEU A 1 218 ? -3.92419  -23.08671 -10.81957 1.000 51.82012  ? 178 LEU A CB  1 
ATOM   1300 C CG  . LEU A 1 218 ? -3.94026  -21.68294 -11.42162 1.000 58.55618  ? 178 LEU A CG  1 
ATOM   1301 C CD1 . LEU A 1 218 ? -5.35845  -21.28915 -11.80946 1.000 48.45563  ? 178 LEU A CD1 1 
ATOM   1302 C CD2 . LEU A 1 218 ? -3.34145  -20.67614 -10.44851 1.000 47.45887  ? 178 LEU A CD2 1 
ATOM   1303 N N   . ILE A 1 219 ? -3.03561  -24.92600 -8.25223  1.000 59.41476  ? 179 ILE A N   1 
ATOM   1304 C CA  . ILE A 1 219 ? -3.47892  -26.12235 -7.54809  1.000 56.87082  ? 179 ILE A CA  1 
ATOM   1305 C C   . ILE A 1 219 ? -5.00027  -26.07766 -7.44975  1.000 63.51623  ? 179 ILE A C   1 
ATOM   1306 O O   . ILE A 1 219 ? -5.58196  -25.05035 -7.07836  1.000 55.44913  ? 179 ILE A O   1 
ATOM   1307 C CB  . ILE A 1 219 ? -2.81774  -26.22600 -6.16062  1.000 54.70833  ? 179 ILE A CB  1 
ATOM   1308 C CG1 . ILE A 1 219 ? -3.18816  -27.54647 -5.48357  1.000 65.69918  ? 179 ILE A CG1 1 
ATOM   1309 C CG2 . ILE A 1 219 ? -3.16102  -25.02958 -5.28026  1.000 55.70195  ? 179 ILE A CG2 1 
ATOM   1310 C CD1 . ILE A 1 219 ? -2.52757  -28.74683 -6.12979  1.000 62.05776  ? 179 ILE A CD1 1 
ATOM   1311 N N   . ILE A 1 220 ? -5.65034  -27.17732 -7.81865  1.000 63.95759  ? 180 ILE A N   1 
ATOM   1312 C CA  . ILE A 1 220 ? -7.11052  -27.22251 -7.89047  1.000 63.28286  ? 180 ILE A CA  1 
ATOM   1313 C C   . ILE A 1 220 ? -7.63358  -28.44855 -7.15023  1.000 63.40567  ? 180 ILE A C   1 
ATOM   1314 O O   . ILE A 1 220 ? -7.20448  -29.57553 -7.43554  1.000 65.95315  ? 180 ILE A O   1 
ATOM   1315 C CB  . ILE A 1 220 ? -7.59367  -27.20754 -9.34950  1.000 71.22218  ? 180 ILE A CB  1 
ATOM   1316 C CG1 . ILE A 1 220 ? -7.17235  -25.90381 -10.03324 1.000 69.34816  ? 180 ILE A CG1 1 
ATOM   1317 C CG2 . ILE A 1 220 ? -9.10339  -27.39939 -9.41297  1.000 56.15325  ? 180 ILE A CG2 1 
ATOM   1318 C CD1 . ILE A 1 220 ? -7.32486  -25.91857 -11.53569 1.000 74.97434  ? 180 ILE A CD1 1 
ATOM   1319 N N   . PRO A 1 221 ? -8.55326  -28.28335 -6.20224  1.000 60.93082  ? 181 PRO A N   1 
ATOM   1320 C CA  . PRO A 1 221 ? -9.08945  -29.44167 -5.48166  1.000 59.75084  ? 181 PRO A CA  1 
ATOM   1321 C C   . PRO A 1 221 ? -10.15599 -30.16602 -6.28890  1.000 58.35374  ? 181 PRO A C   1 
ATOM   1322 O O   . PRO A 1 221 ? -11.00648 -29.54754 -6.93394  1.000 53.88821  ? 181 PRO A O   1 
ATOM   1323 C CB  . PRO A 1 221 ? -9.68709  -28.81204 -4.21909  1.000 50.47564  ? 181 PRO A CB  1 
ATOM   1324 C CG  . PRO A 1 221 ? -10.15483 -27.47340 -4.68939  1.000 51.76733  ? 181 PRO A CG  1 
ATOM   1325 C CD  . PRO A 1 221 ? -9.19389  -27.02785 -5.77613  1.000 59.53170  ? 181 PRO A CD  1 
ATOM   1326 N N   . ILE A 1 222 ? -10.09643 -31.49768 -6.25771  1.000 64.27496  ? 182 ILE A N   1 
ATOM   1327 C CA  . ILE A 1 222 ? -11.09848 -32.33801 -6.89718  1.000 62.60080  ? 182 ILE A CA  1 
ATOM   1328 C C   . ILE A 1 222 ? -11.81854 -33.23430 -5.89662  1.000 61.53822  ? 182 ILE A C   1 
ATOM   1329 O O   . ILE A 1 222 ? -12.57215 -34.12287 -6.29630  1.000 64.09014  ? 182 ILE A O   1 
ATOM   1330 C CB  . ILE A 1 222 ? -10.48674 -33.17126 -8.04072  1.000 67.71581  ? 182 ILE A CB  1 
ATOM   1331 C CG1 . ILE A 1 222 ? -9.33235  -34.03128 -7.52712  1.000 71.63840  ? 182 ILE A CG1 1 
ATOM   1332 C CG2 . ILE A 1 222 ? -10.01557 -32.26396 -9.16426  1.000 61.18619  ? 182 ILE A CG2 1 
ATOM   1333 C CD1 . ILE A 1 222 ? -8.81073  -35.01517 -8.54616  1.000 58.66564  ? 182 ILE A CD1 1 
ATOM   1334 N N   . GLY A 1 223 ? -11.60494 -33.01849 -4.60757  1.000 52.88124  ? 183 GLY A N   1 
ATOM   1335 C CA  . GLY A 1 223 ? -12.31290 -33.73070 -3.56692  1.000 48.84252  ? 183 GLY A CA  1 
ATOM   1336 C C   . GLY A 1 223 ? -11.42975 -34.75091 -2.86227  1.000 56.08562  ? 183 GLY A C   1 
ATOM   1337 O O   . GLY A 1 223 ? -10.42561 -35.23152 -3.39646  1.000 61.37431  ? 183 GLY A O   1 
ATOM   1338 N N   . THR A 1 224 ? -11.84402 -35.09355 -1.63771  1.000 56.45674  ? 184 THR A N   1 
ATOM   1339 C CA  . THR A 1 224 ? -11.19677 -36.09517 -0.79178  1.000 62.51086  ? 184 THR A CA  1 
ATOM   1340 C C   . THR A 1 224 ? -9.67624  -35.99451 -0.80352  1.000 53.16276  ? 184 THR A C   1 
ATOM   1341 O O   . THR A 1 224 ? -8.98232  -37.01061 -0.91117  1.000 58.77363  ? 184 THR A O   1 
ATOM   1342 C CB  . THR A 1 224 ? -11.62888 -37.50652 -1.20595  1.000 63.83775  ? 184 THR A CB  1 
ATOM   1343 O OG1 . THR A 1 224 ? -11.24839 -37.76025 -2.56431  1.000 67.32045  ? 184 THR A OG1 1 
ATOM   1344 C CG2 . THR A 1 224 ? -13.12941 -37.65910 -1.06510  1.000 63.96558  ? 184 THR A CG2 1 
ATOM   1345 N N   . GLY A 1 225 ? -9.15066  -34.77598 -0.68840  1.000 55.03522  ? 185 GLY A N   1 
ATOM   1346 C CA  . GLY A 1 225 ? -7.72324  -34.56341 -0.59839  1.000 49.06428  ? 185 GLY A CA  1 
ATOM   1347 C C   . GLY A 1 225 ? -6.97315  -34.67386 -1.90489  1.000 46.65850  ? 185 GLY A C   1 
ATOM   1348 O O   . GLY A 1 225 ? -5.76829  -34.39172 -1.93180  1.000 58.46724  ? 185 GLY A O   1 
ATOM   1349 N N   . LEU A 1 226 ? -7.63590  -35.07125 -2.98647  1.000 51.00062  ? 186 LEU A N   1 
ATOM   1350 C CA  . LEU A 1 226 ? -6.98736  -35.16458 -4.28341  1.000 53.12537  ? 186 LEU A CA  1 
ATOM   1351 C C   . LEU A 1 226 ? -6.99454  -33.80459 -4.96860  1.000 62.45970  ? 186 LEU A C   1 
ATOM   1352 O O   . LEU A 1 226 ? -7.89576  -32.98657 -4.76137  1.000 65.27522  ? 186 LEU A O   1 
ATOM   1353 C CB  . LEU A 1 226 ? -7.69143  -36.19951 -5.15906  1.000 52.92408  ? 186 LEU A CB  1 
ATOM   1354 C CG  . LEU A 1 226 ? -7.87673  -37.58393 -4.53243  1.000 60.36034  ? 186 LEU A CG  1 
ATOM   1355 C CD1 . LEU A 1 226 ? -8.68254  -38.48542 -5.45123  1.000 57.73050  ? 186 LEU A CD1 1 
ATOM   1356 C CD2 . LEU A 1 226 ? -6.53338  -38.21274 -4.19811  1.000 45.85929  ? 186 LEU A CD2 1 
ATOM   1357 N N   . HIS A 1 227 ? -5.97539  -33.56134 -5.78942  1.000 54.67791  ? 187 HIS A N   1 
ATOM   1358 C CA  . HIS A 1 227 ? -5.82247  -32.25739 -6.41515  1.000 66.26054  ? 187 HIS A CA  1 
ATOM   1359 C C   . HIS A 1 227 ? -5.43994  -32.39291 -7.88058  1.000 62.31103  ? 187 HIS A C   1 
ATOM   1360 O O   . HIS A 1 227 ? -4.68913  -33.29618 -8.25940  1.000 70.91487  ? 187 HIS A O   1 
ATOM   1361 C CB  . HIS A 1 227 ? -4.77512  -31.41670 -5.67739  1.000 58.03819  ? 187 HIS A CB  1 
ATOM   1362 C CG  . HIS A 1 227 ? -5.15700  -31.08396 -4.27007  1.000 60.44635  ? 187 HIS A CG  1 
ATOM   1363 N ND1 . HIS A 1 227 ? -4.81771  -31.88338 -3.20060  1.000 57.38215  ? 187 HIS A ND1 1 
ATOM   1364 C CD2 . HIS A 1 227 ? -5.86548  -30.05004 -3.75771  1.000 60.20195  ? 187 HIS A CD2 1 
ATOM   1365 C CE1 . HIS A 1 227 ? -5.29170  -31.35171 -2.08837  1.000 58.08426  ? 187 HIS A CE1 1 
ATOM   1366 N NE2 . HIS A 1 227 ? -5.93233  -30.23921 -2.39874  1.000 60.85580  ? 187 HIS A NE2 1 
ATOM   1367 N N   . ARG A 1 228 ? -5.96843  -31.48438 -8.69463  1.000 67.55944  ? 188 ARG A N   1 
ATOM   1368 C CA  . ARG A 1 228 ? -5.61627  -31.35719 -10.09833 1.000 67.16095  ? 188 ARG A CA  1 
ATOM   1369 C C   . ARG A 1 228 ? -4.82102  -30.07358 -10.30793 1.000 72.97959  ? 188 ARG A C   1 
ATOM   1370 O O   . ARG A 1 228 ? -5.04321  -29.06801 -9.62719  1.000 73.69021  ? 188 ARG A O   1 
ATOM   1371 C CB  . ARG A 1 228 ? -6.88629  -31.36531 -10.96017 1.000 69.62141  ? 188 ARG A CB  1 
ATOM   1372 C CG  . ARG A 1 228 ? -6.74777  -30.84911 -12.38128 1.000 75.52302  ? 188 ARG A CG  1 
ATOM   1373 C CD  . ARG A 1 228 ? -8.01730  -30.10899 -12.78906 1.000 78.69681  ? 188 ARG A CD  1 
ATOM   1374 N NE  . ARG A 1 228 ? -9.21515  -30.85494 -12.41631 1.000 70.18345  ? 188 ARG A NE  1 
ATOM   1375 C CZ  . ARG A 1 228 ? -10.44998 -30.37167 -12.45884 1.000 79.36935  ? 188 ARG A CZ  1 
ATOM   1376 N NH1 . ARG A 1 228 ? -10.69448 -29.13161 -12.84888 1.000 84.83612  ? 188 ARG A NH1 1 
ATOM   1377 N NH2 . ARG A 1 228 ? -11.46474 -31.14945 -12.09032 1.000 63.93041  ? 188 ARG A NH2 1 
ATOM   1378 N N   . ARG A 1 229 ? -3.87906  -30.12041 -11.24622 1.000 66.97725  ? 189 ARG A N   1 
ATOM   1379 C CA  . ARG A 1 229 ? -3.02989  -28.98363 -11.57206 1.000 70.86277  ? 189 ARG A CA  1 
ATOM   1380 C C   . ARG A 1 229 ? -3.36215  -28.47457 -12.96883 1.000 72.97627  ? 189 ARG A C   1 
ATOM   1381 O O   . ARG A 1 229 ? -3.57493  -29.26843 -13.89114 1.000 71.88306  ? 189 ARG A O   1 
ATOM   1382 C CB  . ARG A 1 229 ? -1.54909  -29.36697 -11.48006 1.000 60.90318  ? 189 ARG A CB  1 
ATOM   1383 C CG  . ARG A 1 229 ? -0.72570  -28.44853 -10.58919 1.000 70.98982  ? 189 ARG A CG  1 
ATOM   1384 C CD  . ARG A 1 229 ? 0.42884   -29.19228 -9.94078  1.000 77.17342  ? 189 ARG A CD  1 
ATOM   1385 N NE  . ARG A 1 229 ? -0.03429  -30.14246 -8.93699  1.000 94.94609  ? 189 ARG A NE  1 
ATOM   1386 C CZ  . ARG A 1 229 ? 0.75436   -30.97679 -8.27356  1.000 92.87904  ? 189 ARG A CZ  1 
ATOM   1387 N NH1 . ARG A 1 229 ? 2.05857   -31.01646 -8.49213  1.000 95.32546  ? 189 ARG A NH1 1 
ATOM   1388 N NH2 . ARG A 1 229 ? 0.22103   -31.79146 -7.36740  1.000 83.92544  ? 189 ARG A NH2 1 
ATOM   1389 N N   . MET A 1 230 ? -3.41349  -27.15121 -13.12562 1.000 64.13324  ? 190 MET A N   1 
ATOM   1390 C CA  . MET A 1 230 ? -3.61734  -26.54298 -14.43468 1.000 73.74485  ? 190 MET A CA  1 
ATOM   1391 C C   . MET A 1 230 ? -2.54071  -25.49393 -14.66805 1.000 63.14489  ? 190 MET A C   1 
ATOM   1392 O O   . MET A 1 230 ? -2.33190  -24.60763 -13.83138 1.000 53.91220  ? 190 MET A O   1 
ATOM   1393 C CB  . MET A 1 230 ? -5.01902  -25.94322 -14.57682 1.000 74.36383  ? 190 MET A CB  1 
ATOM   1394 C CG  . MET A 1 230 ? -6.05720  -27.00957 -14.90958 1.000 75.79847  ? 190 MET A CG  1 
ATOM   1395 S SD  . MET A 1 230 ? -7.75126  -26.43768 -15.10027 1.000 96.60310  ? 190 MET A SD  1 
ATOM   1396 C CE  . MET A 1 230 ? -7.49854  -24.87402 -15.93093 1.000 79.42444  ? 190 MET A CE  1 
ATOM   1397 N N   . VAL A 1 231 ? -1.85475  -25.61049 -15.80206 1.000 68.13728  ? 191 VAL A N   1 
ATOM   1398 C CA  . VAL A 1 231 ? -0.68092  -24.80602 -16.11567 1.000 69.97552  ? 191 VAL A CA  1 
ATOM   1399 C C   . VAL A 1 231 ? -1.01272  -23.91794 -17.30434 1.000 69.57594  ? 191 VAL A C   1 
ATOM   1400 O O   . VAL A 1 231 ? -1.42051  -24.41265 -18.36291 1.000 65.10890  ? 191 VAL A O   1 
ATOM   1401 C CB  . VAL A 1 231 ? 0.54484   -25.68190 -16.42369 1.000 74.24381  ? 191 VAL A CB  1 
ATOM   1402 C CG1 . VAL A 1 231 ? 1.81151   -24.84409 -16.41390 1.000 61.58101  ? 191 VAL A CG1 1 
ATOM   1403 C CG2 . VAL A 1 231 ? 0.64633   -26.83343 -15.43475 1.000 56.02687  ? 191 VAL A CG2 1 
ATOM   1404 N N   . TYR A 1 232 ? -0.84373  -22.61155 -17.12727 1.000 64.12181  ? 192 TYR A N   1 
ATOM   1405 C CA  . TYR A 1 232 ? -0.96052  -21.64085 -18.20687 1.000 66.29130  ? 192 TYR A CA  1 
ATOM   1406 C C   . TYR A 1 232 ? 0.44616   -21.19306 -18.57430 1.000 70.47818  ? 192 TYR A C   1 
ATOM   1407 O O   . TYR A 1 232 ? 1.18285   -20.69411 -17.71649 1.000 64.97425  ? 192 TYR A O   1 
ATOM   1408 C CB  . TYR A 1 232 ? -1.81658  -20.44749 -17.78468 1.000 60.26686  ? 192 TYR A CB  1 
ATOM   1409 C CG  . TYR A 1 232 ? -3.19016  -20.82341 -17.27820 1.000 59.04883  ? 192 TYR A CG  1 
ATOM   1410 C CD1 . TYR A 1 232 ? -4.24984  -21.01581 -18.15573 1.000 64.45459  ? 192 TYR A CD1 1 
ATOM   1411 C CD2 . TYR A 1 232 ? -3.42591  -20.99273 -15.92081 1.000 53.81822  ? 192 TYR A CD2 1 
ATOM   1412 C CE1 . TYR A 1 232 ? -5.50712  -21.35962 -17.69240 1.000 55.14021  ? 192 TYR A CE1 1 
ATOM   1413 C CE2 . TYR A 1 232 ? -4.67644  -21.33806 -15.44974 1.000 61.01343  ? 192 TYR A CE2 1 
ATOM   1414 C CZ  . TYR A 1 232 ? -5.71214  -21.51965 -16.33838 1.000 65.23456  ? 192 TYR A CZ  1 
ATOM   1415 O OH  . TYR A 1 232 ? -6.95921  -21.85866 -15.87205 1.000 67.22485  ? 192 TYR A OH  1 
ATOM   1416 N N   . VAL A 1 233 ? 0.81486   -21.35871 -19.84214 1.000 76.31108  ? 193 VAL A N   1 
ATOM   1417 C CA  . VAL A 1 233 ? 2.19197   -21.17158 -20.28166 1.000 80.45670  ? 193 VAL A CA  1 
ATOM   1418 C C   . VAL A 1 233 ? 2.23795   -20.11686 -21.37997 1.000 76.59346  ? 193 VAL A C   1 
ATOM   1419 O O   . VAL A 1 233 ? 1.44588   -20.15851 -22.32944 1.000 72.66139  ? 193 VAL A O   1 
ATOM   1420 C CB  . VAL A 1 233 ? 2.81103   -22.49874 -20.76260 1.000 74.04673  ? 193 VAL A CB  1 
ATOM   1421 C CG1 . VAL A 1 233 ? 1.92268   -23.17115 -21.80069 1.000 73.43537  ? 193 VAL A CG1 1 
ATOM   1422 C CG2 . VAL A 1 233 ? 4.20112   -22.26690 -21.32089 1.000 90.87504  ? 193 VAL A CG2 1 
ATOM   1423 N N   . GLU A 1 234 ? 3.15846   -19.16509 -21.23478 1.000 80.16006  ? 194 GLU A N   1 
ATOM   1424 C CA  . GLU A 1 234 ? 3.49736   -18.20326 -22.27869 1.000 86.40449  ? 194 GLU A CA  1 
ATOM   1425 C C   . GLU A 1 234 ? 4.77115   -18.69324 -22.96081 1.000 89.69067  ? 194 GLU A C   1 
ATOM   1426 O O   . GLU A 1 234 ? 5.83807   -18.73229 -22.33895 1.000 91.61912  ? 194 GLU A O   1 
ATOM   1427 C CB  . GLU A 1 234 ? 3.67051   -16.80174 -21.69823 1.000 85.60642  ? 194 GLU A CB  1 
ATOM   1428 C CG  . GLU A 1 234 ? 3.76538   -15.69443 -22.73416 1.000 89.88709  ? 194 GLU A CG  1 
ATOM   1429 C CD  . GLU A 1 234 ? 3.74136   -14.31691 -22.10294 1.000 91.24614  ? 194 GLU A CD  1 
ATOM   1430 O OE1 . GLU A 1 234 ? 3.38465   -14.22106 -20.91039 1.000 83.20282  ? 194 GLU A OE1 1 
ATOM   1431 O OE2 . GLU A 1 234 ? 4.07314   -13.33274 -22.79558 1.000 97.07282  ? 194 GLU A OE2 1 
ATOM   1432 N N   . LEU A 1 235 ? 4.66147   -19.06604 -24.23248 1.000 89.43339  ? 195 LEU A N   1 
ATOM   1433 C CA  . LEU A 1 235 ? 5.75581   -19.72954 -24.92415 1.000 98.37584  ? 195 LEU A CA  1 
ATOM   1434 C C   . LEU A 1 235 ? 6.78907   -18.72493 -25.42952 1.000 102.69857 ? 195 LEU A C   1 
ATOM   1435 O O   . LEU A 1 235 ? 6.52128   -17.52962 -25.58235 1.000 103.11250 ? 195 LEU A O   1 
ATOM   1436 C CB  . LEU A 1 235 ? 5.23023   -20.55495 -26.09831 1.000 91.43889  ? 195 LEU A CB  1 
ATOM   1437 C CG  . LEU A 1 235 ? 4.47454   -21.83586 -25.74998 1.000 100.65477 ? 195 LEU A CG  1 
ATOM   1438 C CD1 . LEU A 1 235 ? 4.10866   -22.58735 -27.01702 1.000 106.17741 ? 195 LEU A CD1 1 
ATOM   1439 C CD2 . LEU A 1 235 ? 5.31078   -22.70519 -24.82680 1.000 103.81581 ? 195 LEU A CD2 1 
ATOM   1440 N N   . GLU A 1 236 ? 7.98985   -19.23736 -25.68635 1.000 104.10845 ? 196 GLU A N   1 
ATOM   1441 C CA  . GLU A 1 236 ? 9.07860   -18.45118 -26.23900 1.000 103.87968 ? 196 GLU A CA  1 
ATOM   1442 C C   . GLU A 1 236 ? 8.89061   -18.25115 -27.74087 1.000 111.85450 ? 196 GLU A C   1 
ATOM   1443 O O   . GLU A 1 236 ? 8.04692   -18.88225 -28.38476 1.000 113.80975 ? 196 GLU A O   1 
ATOM   1444 C CB  . GLU A 1 236 ? 10.42020  -19.13585 -25.97424 1.000 99.68121  ? 196 GLU A CB  1 
ATOM   1445 C CG  . GLU A 1 236 ? 10.83421  -19.19030 -24.51137 1.000 97.92345  ? 196 GLU A CG  1 
ATOM   1446 C CD  . GLU A 1 236 ? 11.46596  -17.89988 -24.02583 1.000 97.92559  ? 196 GLU A CD  1 
ATOM   1447 O OE1 . GLU A 1 236 ? 11.30890  -16.86009 -24.69985 1.000 95.20860  ? 196 GLU A OE1 1 
ATOM   1448 O OE2 . GLU A 1 236 ? 12.12787  -17.92798 -22.96716 1.000 86.56618  ? 196 GLU A OE2 1 
ATOM   1449 N N   . GLU A 1 237 ? 9.70561   -17.35676 -28.30036 1.000 119.29241 ? 197 GLU A N   1 
ATOM   1450 C CA  . GLU A 1 237 ? 9.66546   -17.06829 -29.72869 1.000 120.92494 ? 197 GLU A CA  1 
ATOM   1451 C C   . GLU A 1 237 ? 10.01559  -18.30224 -30.55398 1.000 122.91609 ? 197 GLU A C   1 
ATOM   1452 O O   . GLU A 1 237 ? 11.16754  -18.75281 -30.57053 1.000 116.89027 ? 197 GLU A O   1 
ATOM   1453 C CB  . GLU A 1 237 ? 10.60861  -15.91260 -30.07287 1.000 115.38072 ? 197 GLU A CB  1 
ATOM   1454 C CG  . GLU A 1 237 ? 10.21232  -14.56535 -29.47376 1.000 110.49715 ? 197 GLU A CG  1 
ATOM   1455 C CD  . GLU A 1 237 ? 9.28844   -13.75787 -30.37296 1.000 121.38184 ? 197 GLU A CD  1 
ATOM   1456 O OE1 . GLU A 1 237 ? 8.56297   -14.36179 -31.19062 1.000 122.90177 ? 197 GLU A OE1 1 
ATOM   1457 O OE2 . GLU A 1 237 ? 9.29419   -12.51295 -30.26450 1.000 115.13785 ? 197 GLU A OE2 1 
ATOM   1458 N N   . GLY A 1 238 ? 8.99921   -18.85429 -31.22189 1.000 115.54863 ? 198 GLY A N   1 
ATOM   1459 C CA  . GLY A 1 238 ? 9.12379   -19.93616 -32.17576 1.000 108.85472 ? 198 GLY A CA  1 
ATOM   1460 C C   . GLY A 1 238 ? 9.09320   -21.32788 -31.58626 1.000 119.49717 ? 198 GLY A C   1 
ATOM   1461 O O   . GLY A 1 238 ? 9.22269   -22.30530 -32.33933 1.000 114.45853 ? 198 GLY A O   1 
ATOM   1462 N N   . ALA A 1 239 ? 8.79243   -21.45818 -30.30081 1.000 120.14531 ? 199 ALA A N   1 
ATOM   1463 C CA  . ALA A 1 239 ? 8.63939   -22.78850 -29.74267 1.000 114.38471 ? 199 ALA A CA  1 
ATOM   1464 C C   . ALA A 1 239 ? 7.21215   -23.25757 -29.98751 1.000 117.74213 ? 199 ALA A C   1 
ATOM   1465 O O   . ALA A 1 239 ? 6.27497   -22.45755 -30.04582 1.000 118.99632 ? 199 ALA A O   1 
ATOM   1466 C CB  . ALA A 1 239 ? 8.95655   -22.79377 -28.24520 1.000 99.62826  ? 199 ALA A CB  1 
ATOM   1467 N N   . ASP A 1 240 ? 7.05451   -24.56340 -30.16259 1.000 116.25433 ? 200 ASP A N   1 
ATOM   1468 C CA  . ASP A 1 240 ? 5.75822   -25.16303 -30.44498 1.000 118.86615 ? 200 ASP A CA  1 
ATOM   1469 C C   . ASP A 1 240 ? 5.12008   -25.68709 -29.16425 1.000 116.81163 ? 200 ASP A C   1 
ATOM   1470 O O   . ASP A 1 240 ? 5.80554   -26.20739 -28.27911 1.000 112.85479 ? 200 ASP A O   1 
ATOM   1471 C CB  . ASP A 1 240 ? 5.87332   -26.28072 -31.48270 1.000 109.87659 ? 200 ASP A CB  1 
ATOM   1472 C CG  . ASP A 1 240 ? 6.57746   -27.49889 -30.94912 1.000 116.84297 ? 200 ASP A CG  1 
ATOM   1473 O OD1 . ASP A 1 240 ? 7.66101   -27.34276 -30.34916 1.000 120.79879 ? 200 ASP A OD1 1 
ATOM   1474 O OD2 . ASP A 1 240 ? 6.04357   -28.61461 -31.12129 1.000 113.95673 ? 200 ASP A OD2 1 
ATOM   1475 N N   . PHE A 1 241 ? 3.79912   -25.52926 -29.07280 1.000 109.88276 ? 201 PHE A N   1 
ATOM   1476 C CA  . PHE A 1 241 ? 3.06083   -25.93413 -27.87961 1.000 108.77812 ? 201 PHE A CA  1 
ATOM   1477 C C   . PHE A 1 241 ? 3.09554   -27.44233 -27.65677 1.000 108.05882 ? 201 PHE A C   1 
ATOM   1478 O O   . PHE A 1 241 ? 3.21210   -27.89773 -26.51303 1.000 103.58352 ? 201 PHE A O   1 
ATOM   1479 C CB  . PHE A 1 241 ? 1.60992   -25.45991 -27.98127 1.000 105.11509 ? 201 PHE A CB  1 
ATOM   1480 C CG  . PHE A 1 241 ? 0.78056   -25.77757 -26.76809 1.000 101.87935 ? 201 PHE A CG  1 
ATOM   1481 C CD1 . PHE A 1 241 ? 1.17905   -25.37246 -25.50560 1.000 93.64172  ? 201 PHE A CD1 1 
ATOM   1482 C CD2 . PHE A 1 241 ? -0.39022  -26.50931 -26.89322 1.000 100.25951 ? 201 PHE A CD2 1 
ATOM   1483 C CE1 . PHE A 1 241 ? 0.41534   -25.67422 -24.39258 1.000 85.55399  ? 201 PHE A CE1 1 
ATOM   1484 C CE2 . PHE A 1 241 ? -1.15682  -26.81667 -25.78501 1.000 97.16959  ? 201 PHE A CE2 1 
ATOM   1485 C CZ  . PHE A 1 241 ? -0.75368  -26.39844 -24.53288 1.000 89.11133  ? 201 PHE A CZ  1 
ATOM   1486 N N   . ALA A 1 242 ? 2.98664   -28.23200 -28.72898 1.000 105.62740 ? 202 ALA A N   1 
ATOM   1487 C CA  . ALA A 1 242 ? 2.82640   -29.67657 -28.57436 1.000 106.36072 ? 202 ALA A CA  1 
ATOM   1488 C C   . ALA A 1 242 ? 3.99430   -30.32218 -27.83205 1.000 113.13247 ? 202 ALA A C   1 
ATOM   1489 O O   . ALA A 1 242 ? 3.78708   -31.23258 -27.02204 1.000 116.95775 ? 202 ALA A O   1 
ATOM   1490 C CB  . ALA A 1 242 ? 2.64235   -30.32364 -29.94711 1.000 106.63605 ? 202 ALA A CB  1 
ATOM   1491 N N   . THR A 1 243 ? 5.22472   -29.86819 -28.07850 1.000 108.66097 ? 203 THR A N   1 
ATOM   1492 C CA  . THR A 1 243 ? 6.36679   -30.46875 -27.39023 1.000 110.80219 ? 203 THR A CA  1 
ATOM   1493 C C   . THR A 1 243 ? 6.48482   -29.97325 -25.95314 1.000 109.66683 ? 203 THR A C   1 
ATOM   1494 O O   . THR A 1 243 ? 6.67652   -30.77189 -25.02896 1.000 106.08819 ? 203 THR A O   1 
ATOM   1495 C CB  . THR A 1 243 ? 7.66496   -30.20555 -28.15559 1.000 115.45939 ? 203 THR A CB  1 
ATOM   1496 O OG1 . THR A 1 243 ? 7.68598   -28.85282 -28.62275 1.000 117.95027 ? 203 THR A OG1 1 
ATOM   1497 C CG2 . THR A 1 243 ? 7.79497   -31.16506 -29.33184 1.000 118.13602 ? 203 THR A CG2 1 
ATOM   1498 N N   . VAL A 1 244 ? 6.37895   -28.65665 -25.74906 1.000 110.83522 ? 204 VAL A N   1 
ATOM   1499 C CA  . VAL A 1 244 ? 6.48806   -28.09829 -24.40423 1.000 110.69817 ? 204 VAL A CA  1 
ATOM   1500 C C   . VAL A 1 244 ? 5.37436   -28.63095 -23.51476 1.000 109.02521 ? 204 VAL A C   1 
ATOM   1501 O O   . VAL A 1 244 ? 5.54957   -28.76455 -22.29692 1.000 106.67835 ? 204 VAL A O   1 
ATOM   1502 C CB  . VAL A 1 244 ? 6.48333   -26.55725 -24.46513 1.000 102.31688 ? 204 VAL A CB  1 
ATOM   1503 C CG1 . VAL A 1 244 ? 6.80344   -25.96631 -23.09914 1.000 98.72435  ? 204 VAL A CG1 1 
ATOM   1504 C CG2 . VAL A 1 244 ? 7.47491   -26.06747 -25.50696 1.000 101.58308 ? 204 VAL A CG2 1 
ATOM   1505 N N   . LYS A 1 245 ? 4.21434   -28.93914 -24.09898 1.000 98.20684  ? 205 LYS A N   1 
ATOM   1506 C CA  . LYS A 1 245 ? 3.16884   -29.61901 -23.34320 1.000 103.60376 ? 205 LYS A CA  1 
ATOM   1507 C C   . LYS A 1 245 ? 3.65240   -30.97840 -22.84472 1.000 110.38853 ? 205 LYS A C   1 
ATOM   1508 O O   . LYS A 1 245 ? 3.34260   -31.37817 -21.71642 1.000 102.95290 ? 205 LYS A O   1 
ATOM   1509 C CB  . LYS A 1 245 ? 1.90863   -29.76472 -24.19924 1.000 100.25836 ? 205 LYS A CB  1 
ATOM   1510 C CG  . LYS A 1 245 ? 0.71330   -30.34986 -23.46070 1.000 79.89129  ? 205 LYS A CG  1 
ATOM   1511 C CD  . LYS A 1 245 ? -0.51818  -30.41431 -24.35513 1.000 90.25146  ? 205 LYS A CD  1 
ATOM   1512 C CE  . LYS A 1 245 ? -1.67070  -31.13231 -23.66648 1.000 99.77498  ? 205 LYS A CE  1 
ATOM   1513 N NZ  . LYS A 1 245 ? -2.88165  -31.21023 -24.53086 1.000 91.57831  ? 205 LYS A NZ  1 
ATOM   1514 N N   . GLU A 1 246 ? 4.41758   -31.70449 -23.67194 1.000 116.55429 ? 206 GLU A N   1 
ATOM   1515 C CA  . GLU A 1 246 ? 4.89331   -33.03535 -23.30006 1.000 117.95752 ? 206 GLU A CA  1 
ATOM   1516 C C   . GLU A 1 246 ? 6.12936   -33.02058 -22.40901 1.000 112.36324 ? 206 GLU A C   1 
ATOM   1517 O O   . GLU A 1 246 ? 6.54573   -34.08628 -21.93726 1.000 117.56345 ? 206 GLU A O   1 
ATOM   1518 C CB  . GLU A 1 246 ? 5.23986   -33.84960 -24.54723 1.000 128.13064 ? 206 GLU A CB  1 
ATOM   1519 C CG  . GLU A 1 246 ? 4.13896   -34.00113 -25.56855 1.000 127.48079 ? 206 GLU A CG  1 
ATOM   1520 C CD  . GLU A 1 246 ? 2.83045   -34.41410 -24.95211 1.000 127.29039 ? 206 GLU A CD  1 
ATOM   1521 O OE1 . GLU A 1 246 ? 2.81027   -35.45372 -24.26436 1.000 127.37167 ? 206 GLU A OE1 1 
ATOM   1522 O OE2 . GLU A 1 246 ? 1.82377   -33.70667 -25.16172 1.000 122.49621 ? 206 GLU A OE2 1 
ATOM   1523 N N   . ARG A 1 247 ? 6.70541   -31.85120 -22.13728 1.000 99.06671  ? 207 ARG A N   1 
ATOM   1524 C CA  . ARG A 1 247 ? 7.84052   -31.76684 -21.22790 1.000 98.71411  ? 207 ARG A CA  1 
ATOM   1525 C C   . ARG A 1 247 ? 7.40276   -31.31596 -19.84911 1.000 111.82259 ? 207 ARG A C   1 
ATOM   1526 O O   . ARG A 1 247 ? 8.12193   -31.54037 -18.86704 1.000 113.53003 ? 207 ARG A O   1 
ATOM   1527 C CB  . ARG A 1 247 ? 8.92025   -30.82434 -21.77888 1.000 100.63670 ? 207 ARG A CB  1 
ATOM   1528 C CG  . ARG A 1 247 ? 9.65019   -31.36195 -23.00837 1.000 109.62970 ? 207 ARG A CG  1 
ATOM   1529 C CD  . ARG A 1 247 ? 10.48140  -30.27940 -23.69953 1.000 111.85386 ? 207 ARG A CD  1 
ATOM   1530 N NE  . ARG A 1 247 ? 11.21065  -30.80560 -24.84948 1.000 125.83129 ? 207 ARG A NE  1 
ATOM   1531 C CZ  . ARG A 1 247 ? 12.49343  -31.14608 -24.84415 1.000 138.42701 ? 207 ARG A CZ  1 
ATOM   1532 N NH1 . ARG A 1 247 ? 13.23847  -31.02457 -23.75738 1.000 136.04473 ? 207 ARG A NH1 1 
ATOM   1533 N NH2 . ARG A 1 247 ? 13.04233  -31.62380 -25.95798 1.000 129.83105 ? 207 ARG A NH2 1 
ATOM   1534 N N   . ILE A 1 248 ? 6.25054   -30.65741 -19.78059 1.000 111.74925 ? 208 ILE A N   1 
ATOM   1535 C CA  . ILE A 1 248 ? 5.61697   -30.33711 -18.51531 1.000 105.81863 ? 208 ILE A CA  1 
ATOM   1536 C C   . ILE A 1 248 ? 4.83067   -31.54051 -18.01395 1.000 104.56343 ? 208 ILE A C   1 
ATOM   1537 O O   . ILE A 1 248 ? 4.86631   -31.87250 -16.82420 1.000 105.44356 ? 208 ILE A O   1 
ATOM   1538 C CB  . ILE A 1 248 ? 4.71513   -29.10996 -18.71418 1.000 102.78858 ? 208 ILE A CB  1 
ATOM   1539 C CG1 . ILE A 1 248 ? 5.55728   -27.88707 -19.06731 1.000 107.82479 ? 208 ILE A CG1 1 
ATOM   1540 C CG2 . ILE A 1 248 ? 3.88805   -28.85706 -17.46599 1.000 104.91875 ? 208 ILE A CG2 1 
ATOM   1541 C CD1 . ILE A 1 248 ? 4.73140   -26.69182 -19.47429 1.000 99.37407  ? 208 ILE A CD1 1 
ATOM   1542 N N   . LEU A 1 249 ? 4.11930   -32.21889 -18.92109 1.000 89.90791  ? 209 LEU A N   1 
ATOM   1543 C CA  . LEU A 1 249 ? 3.31394   -33.37747 -18.55315 1.000 94.01728  ? 209 LEU A CA  1 
ATOM   1544 C C   . LEU A 1 249 ? 4.15887   -34.58482 -18.16831 1.000 112.58317 ? 209 LEU A C   1 
ATOM   1545 O O   . LEU A 1 249 ? 3.65421   -35.48070 -17.48520 1.000 106.51055 ? 209 LEU A O   1 
ATOM   1546 C CB  . LEU A 1 249 ? 2.37482   -33.74570 -19.70422 1.000 99.35637  ? 209 LEU A CB  1 
ATOM   1547 C CG  . LEU A 1 249 ? 0.93106   -33.24941 -19.59167 1.000 90.38966  ? 209 LEU A CG  1 
ATOM   1548 C CD1 . LEU A 1 249 ? 0.16212   -33.55132 -20.86945 1.000 77.13717  ? 209 LEU A CD1 1 
ATOM   1549 C CD2 . LEU A 1 249 ? 0.23568   -33.85802 -18.38223 1.000 95.98991  ? 209 LEU A CD2 1 
ATOM   1550 N N   . GLN A 1 250 ? 5.42457   -34.63273 -18.58232 1.000 116.13216 ? 210 GLN A N   1 
ATOM   1551 C CA  . GLN A 1 250 ? 6.34333   -35.68275 -18.15761 1.000 109.87200 ? 210 GLN A CA  1 
ATOM   1552 C C   . GLN A 1 250 ? 7.39761   -35.17147 -17.18126 1.000 113.17553 ? 210 GLN A C   1 
ATOM   1553 O O   . GLN A 1 250 ? 8.32546   -35.91265 -16.83708 1.000 114.69936 ? 210 GLN A O   1 
ATOM   1554 C CB  . GLN A 1 250 ? 7.00568   -36.34489 -19.37149 1.000 108.33088 ? 210 GLN A CB  1 
ATOM   1555 C CG  . GLN A 1 250 ? 6.09175   -37.31576 -20.11569 1.000 112.88718 ? 210 GLN A CG  1 
ATOM   1556 C CD  . GLN A 1 250 ? 5.76826   -38.55982 -19.30385 1.000 119.55886 ? 210 GLN A CD  1 
ATOM   1557 O OE1 . GLN A 1 250 ? 4.61436   -38.79962 -18.94389 1.000 107.10351 ? 210 GLN A OE1 1 
ATOM   1558 N NE2 . GLN A 1 250 ? 6.78315   -39.36751 -19.03139 1.000 114.88065 ? 210 GLN A NE2 1 
ATOM   1559 N N   . ASP A 1 251 ? 7.27303   -33.92944 -16.72523 1.000 108.99554 ? 211 ASP A N   1 
ATOM   1560 C CA  . ASP A 1 251 ? 8.12157   -33.44000 -15.64946 1.000 108.12927 ? 211 ASP A CA  1 
ATOM   1561 C C   . ASP A 1 251 ? 7.77376   -34.16806 -14.35367 1.000 111.03691 ? 211 ASP A C   1 
ATOM   1562 O O   . ASP A 1 251 ? 6.59499   -34.41259 -14.08374 1.000 107.72633 ? 211 ASP A O   1 
ATOM   1563 C CB  . ASP A 1 251 ? 7.93266   -31.93065 -15.47799 1.000 107.32932 ? 211 ASP A CB  1 
ATOM   1564 C CG  . ASP A 1 251 ? 8.93809   -31.30972 -14.52691 1.000 107.05499 ? 211 ASP A CG  1 
ATOM   1565 O OD1 . ASP A 1 251 ? 8.81041   -31.51240 -13.30130 1.000 95.86419  ? 211 ASP A OD1 1 
ATOM   1566 O OD2 . ASP A 1 251 ? 9.85881   -30.61570 -15.00808 1.000 114.58029 ? 211 ASP A OD2 1 
ATOM   1567 N N   . PRO A 1 252 ? 8.77314   -34.48412 -13.50795 1.000 113.41698 ? 212 PRO A N   1 
ATOM   1568 C CA  . PRO A 1 252 ? 8.51085   -35.29828 -12.30903 1.000 113.30523 ? 212 PRO A CA  1 
ATOM   1569 C C   . PRO A 1 252 ? 7.38925   -34.77097 -11.42446 1.000 112.83765 ? 212 PRO A C   1 
ATOM   1570 O O   . PRO A 1 252 ? 6.78714   -35.53154 -10.65941 1.000 109.86795 ? 212 PRO A O   1 
ATOM   1571 C CB  . PRO A 1 252 ? 9.85630   -35.26475 -11.57502 1.000 113.43930 ? 212 PRO A CB  1 
ATOM   1572 C CG  . PRO A 1 252 ? 10.85828  -35.13704 -12.66933 1.000 111.19881 ? 212 PRO A CG  1 
ATOM   1573 C CD  . PRO A 1 252 ? 10.21743  -34.28416 -13.73268 1.000 109.24787 ? 212 PRO A CD  1 
ATOM   1574 N N   . LEU A 1 253 ? 7.09692   -33.47378 -11.52021 1.000 108.16790 ? 213 LEU A N   1 
ATOM   1575 C CA  . LEU A 1 253 ? 6.06260   -32.87731 -10.68663 1.000 95.77749  ? 213 LEU A CA  1 
ATOM   1576 C C   . LEU A 1 253 ? 4.64949   -33.14546 -11.19974 1.000 98.00908  ? 213 LEU A C   1 
ATOM   1577 O O   . LEU A 1 253 ? 3.70013   -33.06136 -10.41309 1.000 105.17765 ? 213 LEU A O   1 
ATOM   1578 C CB  . LEU A 1 253 ? 6.29238   -31.36656 -10.57495 1.000 95.72484  ? 213 LEU A CB  1 
ATOM   1579 C CG  . LEU A 1 253 ? 5.50867   -30.59390 -9.51157  1.000 104.96697 ? 213 LEU A CG  1 
ATOM   1580 C CD1 . LEU A 1 253 ? 5.76739   -31.16672 -8.12585  1.000 108.16602 ? 213 LEU A CD1 1 
ATOM   1581 C CD2 . LEU A 1 253 ? 5.85774   -29.11433 -9.55838  1.000 94.98485  ? 213 LEU A CD2 1 
ATOM   1582 N N   . PHE A 1 254 ? 4.47813   -33.47895 -12.48620 1.000 98.57929  ? 214 PHE A N   1 
ATOM   1583 C CA  . PHE A 1 254 ? 3.14134   -33.58794 -13.06621 1.000 104.42217 ? 214 PHE A CA  1 
ATOM   1584 C C   . PHE A 1 254 ? 2.91403   -34.90407 -13.80810 1.000 108.73960 ? 214 PHE A C   1 
ATOM   1585 O O   . PHE A 1 254 ? 2.09007   -34.95608 -14.72568 1.000 106.96415 ? 214 PHE A O   1 
ATOM   1586 C CB  . PHE A 1 254 ? 2.84782   -32.41910 -14.01066 1.000 100.59286 ? 214 PHE A CB  1 
ATOM   1587 C CG  . PHE A 1 254 ? 3.33139   -31.08242 -13.51744 1.000 102.55085 ? 214 PHE A CG  1 
ATOM   1588 C CD1 . PHE A 1 254 ? 4.60528   -30.63269 -13.82419 1.000 99.96819  ? 214 PHE A CD1 1 
ATOM   1589 C CD2 . PHE A 1 254 ? 2.49675   -30.25924 -12.77702 1.000 94.42296  ? 214 PHE A CD2 1 
ATOM   1590 C CE1 . PHE A 1 254 ? 5.04695   -29.39930 -13.38304 1.000 96.76177  ? 214 PHE A CE1 1 
ATOM   1591 C CE2 . PHE A 1 254 ? 2.93352   -29.02211 -12.33447 1.000 92.51244  ? 214 PHE A CE2 1 
ATOM   1592 C CZ  . PHE A 1 254 ? 4.20993   -28.59318 -12.63860 1.000 95.55525  ? 214 PHE A CZ  1 
ATOM   1593 N N   . VAL A 1 255 ? 3.60412   -35.97993 -13.43831 1.000 116.28594 ? 215 VAL A N   1 
ATOM   1594 C CA  . VAL A 1 255 ? 3.42247   -37.23984 -14.16134 1.000 104.47909 ? 215 VAL A CA  1 
ATOM   1595 C C   . VAL A 1 255 ? 2.32617   -38.08183 -13.52813 1.000 98.77498  ? 215 VAL A C   1 
ATOM   1596 O O   . VAL A 1 255 ? 1.45111   -38.60867 -14.22023 1.000 104.03242 ? 215 VAL A O   1 
ATOM   1597 C CB  . VAL A 1 255 ? 4.74699   -38.02916 -14.23355 1.000 102.04743 ? 215 VAL A CB  1 
ATOM   1598 C CG1 . VAL A 1 255 ? 4.53299   -39.34010 -14.97913 1.000 108.34986 ? 215 VAL A CG1 1 
ATOM   1599 C CG2 . VAL A 1 255 ? 5.81805   -37.21759 -14.91097 1.000 108.64947 ? 215 VAL A CG2 1 
ATOM   1600 N N   . HIS A 1 256 ? 2.35263   -38.20935 -12.20597 1.000 97.05256  ? 216 HIS A N   1 
ATOM   1601 C CA  . HIS A 1 256 ? 1.37611   -38.99858 -11.47116 1.000 96.33953  ? 216 HIS A CA  1 
ATOM   1602 C C   . HIS A 1 256 ? 0.16853   -38.17964 -11.03454 1.000 106.37270 ? 216 HIS A C   1 
ATOM   1603 O O   . HIS A 1 256 ? -0.73972  -38.72710 -10.40061 1.000 110.93204 ? 216 HIS A O   1 
ATOM   1604 C CB  . HIS A 1 256 ? 2.05021   -39.66426 -10.26934 1.000 93.22970  ? 216 HIS A CB  1 
ATOM   1605 C CG  . HIS A 1 256 ? 3.38046   -40.27062 -10.59557 1.000 102.70277 ? 216 HIS A CG  1 
ATOM   1606 N ND1 . HIS A 1 256 ? 3.53038   -41.26356 -11.54022 1.000 97.78618  ? 216 HIS A ND1 1 
ATOM   1607 C CD2 . HIS A 1 256 ? 4.62217   -40.01353 -10.12025 1.000 92.68242  ? 216 HIS A CD2 1 
ATOM   1608 C CE1 . HIS A 1 256 ? 4.80524   -41.59836 -11.62619 1.000 95.94645  ? 216 HIS A CE1 1 
ATOM   1609 N NE2 . HIS A 1 256 ? 5.48910   -40.85477 -10.77512 1.000 97.89239  ? 216 HIS A NE2 1 
ATOM   1610 N N   . ASP A 1 257 ? 0.14410   -36.88824 -11.35284 1.000 105.67162 ? 217 ASP A N   1 
ATOM   1611 C CA  . ASP A 1 257 ? -0.97063  -36.00314 -11.05043 1.000 95.67413  ? 217 ASP A CA  1 
ATOM   1612 C C   . ASP A 1 257 ? -1.64479  -35.57809 -12.34773 1.000 90.85404  ? 217 ASP A C   1 
ATOM   1613 O O   . ASP A 1 257 ? -0.97053  -35.29224 -13.34240 1.000 93.57819  ? 217 ASP A O   1 
ATOM   1614 C CB  . ASP A 1 257 ? -0.49105  -34.76560 -10.28652 1.000 100.11044 ? 217 ASP A CB  1 
ATOM   1615 C CG  . ASP A 1 257 ? 0.26551   -35.11547 -9.01993  1.000 105.88865 ? 217 ASP A CG  1 
ATOM   1616 O OD1 . ASP A 1 257 ? -0.08696  -36.12472 -8.37466  1.000 104.30837 ? 217 ASP A OD1 1 
ATOM   1617 O OD2 . ASP A 1 257 ? 1.24124   -34.40642 -8.69371  1.000 98.25875  ? 217 ASP A OD2 1 
ATOM   1618 N N   . GLU A 1 258 ? -2.97559  -35.55230 -12.33786 1.000 74.45831  ? 218 GLU A N   1 
ATOM   1619 C CA  . GLU A 1 258 ? -3.72610  -35.05355 -13.48405 1.000 76.82497  ? 218 GLU A CA  1 
ATOM   1620 C C   . GLU A 1 258 ? -3.35653  -33.60067 -13.75838 1.000 85.94255  ? 218 GLU A C   1 
ATOM   1621 O O   . GLU A 1 258 ? -3.47652  -32.74386 -12.87680 1.000 78.58067  ? 218 GLU A O   1 
ATOM   1622 C CB  . GLU A 1 258 ? -5.22541  -35.18898 -13.22339 1.000 69.64700  ? 218 GLU A CB  1 
ATOM   1623 C CG  . GLU A 1 258 ? -6.10510  -34.48762 -14.24346 1.000 82.52236  ? 218 GLU A CG  1 
ATOM   1624 C CD  . GLU A 1 258 ? -7.54067  -34.35590 -13.77489 1.000 89.88644  ? 218 GLU A CD  1 
ATOM   1625 O OE1 . GLU A 1 258 ? -7.88482  -34.94866 -12.73022 1.000 75.47528  ? 218 GLU A OE1 1 
ATOM   1626 O OE2 . GLU A 1 258 ? -8.32389  -33.65636 -14.44891 1.000 86.63650  ? 218 GLU A OE2 1 
ATOM   1627 N N   . THR A 1 259 ? -2.90711  -33.32220 -14.98138 1.000 85.21891  ? 219 THR A N   1 
ATOM   1628 C CA  . THR A 1 259 ? -2.37448  -32.00888 -15.32033 1.000 79.31269  ? 219 THR A CA  1 
ATOM   1629 C C   . THR A 1 259 ? -2.91518  -31.54418 -16.66347 1.000 77.09167  ? 219 THR A C   1 
ATOM   1630 O O   . THR A 1 259 ? -2.86215  -32.28554 -17.64932 1.000 81.53503  ? 219 THR A O   1 
ATOM   1631 C CB  . THR A 1 259 ? -0.84304  -32.02932 -15.35434 1.000 74.48718  ? 219 THR A CB  1 
ATOM   1632 O OG1 . THR A 1 259 ? -0.34460  -32.44577 -14.07769 1.000 72.16533  ? 219 THR A OG1 1 
ATOM   1633 C CG2 . THR A 1 259 ? -0.30161  -30.64792 -15.67843 1.000 71.31044  ? 219 THR A CG2 1 
ATOM   1634 N N   . HIS A 1 260 ? -3.43821  -30.32153 -16.69205 1.000 68.30303  ? 220 HIS A N   1 
ATOM   1635 C CA  . HIS A 1 260 ? -3.89237  -29.67462 -17.91348 1.000 65.02526  ? 220 HIS A CA  1 
ATOM   1636 C C   . HIS A 1 260 ? -2.95953  -28.51284 -18.23101 1.000 73.54225  ? 220 HIS A C   1 
ATOM   1637 O O   . HIS A 1 260 ? -2.54505  -27.77778 -17.32963 1.000 81.65130  ? 220 HIS A O   1 
ATOM   1638 C CB  . HIS A 1 260 ? -5.33134  -29.17132 -17.76451 1.000 79.30966  ? 220 HIS A CB  1 
ATOM   1639 C CG  . HIS A 1 260 ? -6.31982  -30.25095 -17.44730 1.000 80.99783  ? 220 HIS A CG  1 
ATOM   1640 N ND1 . HIS A 1 260 ? -7.19009  -30.76513 -18.38470 1.000 82.86291  ? 220 HIS A ND1 1 
ATOM   1641 C CD2 . HIS A 1 260 ? -6.57487  -30.91394 -16.29400 1.000 75.07522  ? 220 HIS A CD2 1 
ATOM   1642 C CE1 . HIS A 1 260 ? -7.93812  -31.69821 -17.82279 1.000 78.52079  ? 220 HIS A CE1 1 
ATOM   1643 N NE2 . HIS A 1 260 ? -7.58524  -31.80766 -16.55448 1.000 73.75638  ? 220 HIS A NE2 1 
ATOM   1644 N N   . VAL A 1 261 ? -2.63238  -28.34222 -19.50973 1.000 71.15244  ? 221 VAL A N   1 
ATOM   1645 C CA  . VAL A 1 261 ? -1.75274  -27.26944 -19.96186 1.000 76.93329  ? 221 VAL A CA  1 
ATOM   1646 C C   . VAL A 1 261 ? -2.47858  -26.46182 -21.02816 1.000 82.20251  ? 221 VAL A C   1 
ATOM   1647 O O   . VAL A 1 261 ? -3.08688  -27.03415 -21.94004 1.000 80.25647  ? 221 VAL A O   1 
ATOM   1648 C CB  . VAL A 1 261 ? -0.41830  -27.81510 -20.50196 1.000 74.73269  ? 221 VAL A CB  1 
ATOM   1649 C CG1 . VAL A 1 261 ? 0.52481   -26.67070 -20.83598 1.000 74.07655  ? 221 VAL A CG1 1 
ATOM   1650 C CG2 . VAL A 1 261 ? 0.21970   -28.74745 -19.48742 1.000 84.32724  ? 221 VAL A CG2 1 
ATOM   1651 N N   . LEU A 1 262 ? -2.41402  -25.13450 -20.90989 1.000 78.09042  ? 222 LEU A N   1 
ATOM   1652 C CA  . LEU A 1 262 ? -3.02083  -24.21519 -21.86326 1.000 74.04378  ? 222 LEU A CA  1 
ATOM   1653 C C   . LEU A 1 262 ? -2.03381  -23.10629 -22.19821 1.000 79.19335  ? 222 LEU A C   1 
ATOM   1654 O O   . LEU A 1 262 ? -1.30730  -22.62839 -21.32175 1.000 73.48108  ? 222 LEU A O   1 
ATOM   1655 C CB  . LEU A 1 262 ? -4.30811  -23.58500 -21.30096 1.000 70.36597  ? 222 LEU A CB  1 
ATOM   1656 C CG  . LEU A 1 262 ? -5.63263  -24.35444 -21.27885 1.000 77.11870  ? 222 LEU A CG  1 
ATOM   1657 C CD1 . LEU A 1 262 ? -5.61549  -25.48554 -20.25614 1.000 83.59932  ? 222 LEU A CD1 1 
ATOM   1658 C CD2 . LEU A 1 262 ? -6.78038  -23.39698 -20.99803 1.000 79.72156  ? 222 LEU A CD2 1 
ATOM   1659 N N   . GLN A 1 263 ? -2.00167  -22.69873 -23.46390 1.000 77.09332  ? 223 GLN A N   1 
ATOM   1660 C CA  . GLN A 1 263 ? -1.16619  -21.57765 -23.86914 1.000 76.70459  ? 223 GLN A CA  1 
ATOM   1661 C C   . GLN A 1 263 ? -1.98407  -20.29426 -23.81899 1.000 80.86559  ? 223 GLN A C   1 
ATOM   1662 O O   . GLN A 1 263 ? -3.13058  -20.25482 -24.27459 1.000 82.67722  ? 223 GLN A O   1 
ATOM   1663 C CB  . GLN A 1 263 ? -0.59134  -21.78660 -25.27133 1.000 75.99906  ? 223 GLN A CB  1 
ATOM   1664 C CG  . GLN A 1 263 ? 0.48709   -20.77343 -25.63663 1.000 90.72797  ? 223 GLN A CG  1 
ATOM   1665 C CD  . GLN A 1 263 ? 0.93040   -20.87067 -27.08333 1.000 92.88482  ? 223 GLN A CD  1 
ATOM   1666 O OE1 . GLN A 1 263 ? 0.49545   -21.75394 -27.82189 1.000 89.32692  ? 223 GLN A OE1 1 
ATOM   1667 N NE2 . GLN A 1 263 ? 1.80524   -19.95989 -27.49468 1.000 80.07539  ? 223 GLN A NE2 1 
ATOM   1668 N N   . VAL A 1 264 ? -1.38542  -19.24086 -23.26357 1.000 81.21767  ? 224 VAL A N   1 
ATOM   1669 C CA  . VAL A 1 264 ? -2.05428  -17.95852 -23.09871 1.000 71.32760  ? 224 VAL A CA  1 
ATOM   1670 C C   . VAL A 1 264 ? -1.11625  -16.85007 -23.55608 1.000 77.65529  ? 224 VAL A C   1 
ATOM   1671 O O   . VAL A 1 264 ? 0.10235   -17.02196 -23.62937 1.000 84.27169  ? 224 VAL A O   1 
ATOM   1672 C CB  . VAL A 1 264 ? -2.50894  -17.71492 -21.64228 1.000 71.12587  ? 224 VAL A CB  1 
ATOM   1673 C CG1 . VAL A 1 264 ? -3.49179  -18.78839 -21.20266 1.000 63.11234  ? 224 VAL A CG1 1 
ATOM   1674 C CG2 . VAL A 1 264 ? -1.31054  -17.68066 -20.71445 1.000 71.12108  ? 224 VAL A CG2 1 
ATOM   1675 N N   . ASP A 1 265 ? -1.70990  -15.69864 -23.87725 1.000 86.49365  ? 225 ASP A N   1 
ATOM   1676 C CA  . ASP A 1 265 ? -0.92741  -14.56365 -24.35516 1.000 80.89585  ? 225 ASP A CA  1 
ATOM   1677 C C   . ASP A 1 265 ? -0.16344  -13.87670 -23.22736 1.000 78.02393  ? 225 ASP A C   1 
ATOM   1678 O O   . ASP A 1 265 ? 1.01369   -13.53860 -23.39325 1.000 81.96957  ? 225 ASP A O   1 
ATOM   1679 C CB  . ASP A 1 265 ? -1.84036  -13.56175 -25.06324 1.000 80.35788  ? 225 ASP A CB  1 
ATOM   1680 C CG  . ASP A 1 265 ? -2.53051  -14.15723 -26.27583 1.000 89.82811  ? 225 ASP A CG  1 
ATOM   1681 O OD1 . ASP A 1 265 ? -1.91977  -15.01288 -26.95012 1.000 90.70826  ? 225 ASP A OD1 1 
ATOM   1682 O OD2 . ASP A 1 265 ? -3.68401  -13.76850 -26.55371 1.000 86.73962  ? 225 ASP A OD2 1 
ATOM   1683 N N   . ASP A 1 266 ? -0.80691  -13.65931 -22.07925 1.000 69.36498  ? 226 ASP A N   1 
ATOM   1684 C CA  . ASP A 1 266 ? -0.19500  -12.92622 -20.96827 1.000 74.18153  ? 226 ASP A CA  1 
ATOM   1685 C C   . ASP A 1 266 ? -0.56207  -13.63432 -19.66692 1.000 73.04645  ? 226 ASP A C   1 
ATOM   1686 O O   . ASP A 1 266 ? -1.70222  -13.53763 -19.20291 1.000 76.36402  ? 226 ASP A O   1 
ATOM   1687 C CB  . ASP A 1 266 ? -0.65574  -11.47332 -20.96073 1.000 74.91057  ? 226 ASP A CB  1 
ATOM   1688 C CG  . ASP A 1 266 ? 0.17017   -10.60074 -20.03762 1.000 75.19169  ? 226 ASP A CG  1 
ATOM   1689 O OD1 . ASP A 1 266 ? 1.12293   -11.11477 -19.41346 1.000 82.35668  ? 226 ASP A OD1 1 
ATOM   1690 O OD2 . ASP A 1 266 ? -0.13873  -9.39567  -19.93602 1.000 75.76268  ? 226 ASP A OD2 1 
ATOM   1691 N N   . VAL A 1 267 ? 0.40394   -14.35016 -19.08476 1.000 72.42888  ? 227 VAL A N   1 
ATOM   1692 C CA  . VAL A 1 267 ? 0.15020   -15.03559 -17.82050 1.000 71.08904  ? 227 VAL A CA  1 
ATOM   1693 C C   . VAL A 1 267 ? 0.00268   -14.04205 -16.67473 1.000 64.43672  ? 227 VAL A C   1 
ATOM   1694 O O   . VAL A 1 267 ? -0.67805  -14.33141 -15.68291 1.000 65.15017  ? 227 VAL A O   1 
ATOM   1695 C CB  . VAL A 1 267 ? 1.25297   -16.07267 -17.53058 1.000 65.66075  ? 227 VAL A CB  1 
ATOM   1696 C CG1 . VAL A 1 267 ? 1.59914   -16.84400 -18.78762 1.000 73.12213  ? 227 VAL A CG1 1 
ATOM   1697 C CG2 . VAL A 1 267 ? 2.48466   -15.41093 -16.95226 1.000 67.03657  ? 227 VAL A CG2 1 
ATOM   1698 N N   . LYS A 1 268 ? 0.64127   -12.87031 -16.77300 1.000 72.38358  ? 228 LYS A N   1 
ATOM   1699 C CA  . LYS A 1 268 ? 0.52887   -11.88580 -15.70131 1.000 71.36969  ? 228 LYS A CA  1 
ATOM   1700 C C   . LYS A 1 268 ? -0.91096  -11.41210 -15.54708 1.000 63.80062  ? 228 LYS A C   1 
ATOM   1701 O O   . LYS A 1 268 ? -1.32619  -11.02385 -14.44902 1.000 64.49489  ? 228 LYS A O   1 
ATOM   1702 C CB  . LYS A 1 268 ? 1.46978   -10.70668 -15.96288 1.000 72.48398  ? 228 LYS A CB  1 
ATOM   1703 C CG  . LYS A 1 268 ? 1.69526   -9.80734  -14.75022 1.000 90.48175  ? 228 LYS A CG  1 
ATOM   1704 C CD  . LYS A 1 268 ? 0.86740   -8.53338  -14.77583 1.000 82.66590  ? 228 LYS A CD  1 
ATOM   1705 C CE  . LYS A 1 268 ? 1.23669   -7.63507  -13.59930 1.000 78.34235  ? 228 LYS A CE  1 
ATOM   1706 N NZ  . LYS A 1 268 ? 0.61505   -6.28483  -13.68889 1.000 67.88276  ? 228 LYS A NZ  1 
ATOM   1707 N N   . GLN A 1 269 ? -1.68402  -11.44178 -16.63512 1.000 56.25999  ? 229 GLN A N   1 
ATOM   1708 C CA  . GLN A 1 269 ? -3.09516  -11.07815 -16.60783 1.000 57.91537  ? 229 GLN A CA  1 
ATOM   1709 C C   . GLN A 1 269 ? -3.95364  -12.07646 -15.84262 1.000 57.43996  ? 229 GLN A C   1 
ATOM   1710 O O   . GLN A 1 269 ? -5.12266  -11.78164 -15.56989 1.000 55.32190  ? 229 GLN A O   1 
ATOM   1711 C CB  . GLN A 1 269 ? -3.62448  -10.94091 -18.03694 1.000 58.04290  ? 229 GLN A CB  1 
ATOM   1712 C CG  . GLN A 1 269 ? -4.73638  -9.92277  -18.19092 1.000 70.30158  ? 229 GLN A CG  1 
ATOM   1713 C CD  . GLN A 1 269 ? -4.30091  -8.52224  -17.82535 1.000 63.87931  ? 229 GLN A CD  1 
ATOM   1714 O OE1 . GLN A 1 269 ? -3.13233  -8.16399  -17.96883 1.000 69.60539  ? 229 GLN A OE1 1 
ATOM   1715 N NE2 . GLN A 1 269 ? -5.24351  -7.71830  -17.34617 1.000 76.36796  ? 229 GLN A NE2 1 
ATOM   1716 N N   . LEU A 1 270 ? -3.41342  -13.23997 -15.49619 1.000 53.74971  ? 230 LEU A N   1 
ATOM   1717 C CA  . LEU A 1 270 ? -4.17648  -14.28909 -14.83869 1.000 53.83370  ? 230 LEU A CA  1 
ATOM   1718 C C   . LEU A 1 270 ? -3.86450  -14.39960 -13.35267 1.000 52.45970  ? 230 LEU A C   1 
ATOM   1719 O O   . LEU A 1 270 ? -4.50723  -15.18918 -12.65343 1.000 47.69772  ? 230 LEU A O   1 
ATOM   1720 C CB  . LEU A 1 270 ? -3.90436  -15.63159 -15.52518 1.000 44.75055  ? 230 LEU A CB  1 
ATOM   1721 C CG  . LEU A 1 270 ? -4.38857  -15.75146 -16.97252 1.000 54.28594  ? 230 LEU A CG  1 
ATOM   1722 C CD1 . LEU A 1 270 ? -4.00033  -17.09950 -17.56109 1.000 53.33184  ? 230 LEU A CD1 1 
ATOM   1723 C CD2 . LEU A 1 270 ? -5.89013  -15.52411 -17.07483 1.000 64.40632  ? 230 LEU A CD2 1 
ATOM   1724 N N   . ILE A 1 271 ? -2.91095  -13.61966 -12.85602 1.000 52.55136  ? 231 ILE A N   1 
ATOM   1725 C CA  . ILE A 1 271 ? -2.37626  -13.81193 -11.51306 1.000 56.85581  ? 231 ILE A CA  1 
ATOM   1726 C C   . ILE A 1 271 ? -3.29780  -13.17097 -10.48331 1.000 51.93838  ? 231 ILE A C   1 
ATOM   1727 O O   . ILE A 1 271 ? -3.67238  -11.99823 -10.60296 1.000 56.44457  ? 231 ILE A O   1 
ATOM   1728 C CB  . ILE A 1 271 ? -0.94888  -13.24923 -11.41436 1.000 54.20917  ? 231 ILE A CB  1 
ATOM   1729 C CG1 . ILE A 1 271 ? 0.01418   -14.08799 -12.26077 1.000 56.00842  ? 231 ILE A CG1 1 
ATOM   1730 C CG2 . ILE A 1 271 ? -0.49573  -13.16660 -9.96807  1.000 43.30251  ? 231 ILE A CG2 1 
ATOM   1731 C CD1 . ILE A 1 271 ? 1.40012   -13.49268 -12.37361 1.000 59.28380  ? 231 ILE A CD1 1 
ATOM   1732 N N   . ASP A 1 272 ? -3.66807  -13.94942 -9.46858  1.000 48.69869  ? 232 ASP A N   1 
ATOM   1733 C CA  . ASP A 1 272 ? -4.32257  -13.44970 -8.26829  1.000 48.85488  ? 232 ASP A CA  1 
ATOM   1734 C C   . ASP A 1 272 ? -3.83309  -14.27854 -7.09187  1.000 45.21769  ? 232 ASP A C   1 
ATOM   1735 O O   . ASP A 1 272 ? -3.77438  -15.50879 -7.17335  1.000 50.47630  ? 232 ASP A O   1 
ATOM   1736 C CB  . ASP A 1 272 ? -5.85412  -13.51675 -8.37068  1.000 49.43004  ? 232 ASP A CB  1 
ATOM   1737 C CG  . ASP A 1 272 ? -6.54488  -13.29457 -7.02979  1.000 55.80053  ? 232 ASP A CG  1 
ATOM   1738 O OD1 . ASP A 1 272 ? -6.65305  -14.25419 -6.23472  1.000 58.38524  ? 232 ASP A OD1 1 
ATOM   1739 O OD2 . ASP A 1 272 ? -6.97156  -12.15128 -6.76645  1.000 55.77740  ? 232 ASP A OD2 1 
ATOM   1740 N N   . ARG A 1 273 ? -3.47952  -13.60079 -6.00066  1.000 49.65834  ? 233 ARG A N   1 
ATOM   1741 C CA  . ARG A 1 273 ? -2.86772  -14.24593 -4.84788  1.000 51.14084  ? 233 ARG A CA  1 
ATOM   1742 C C   . ARG A 1 273 ? -3.88371  -14.61565 -3.77471  1.000 49.11889  ? 233 ARG A C   1 
ATOM   1743 O O   . ARG A 1 273 ? -3.51387  -14.78960 -2.60827  1.000 54.84565  ? 233 ARG A O   1 
ATOM   1744 C CB  . ARG A 1 273 ? -1.76753  -13.35209 -4.27636  1.000 54.34305  ? 233 ARG A CB  1 
ATOM   1745 C CG  . ARG A 1 273 ? -0.61475  -13.15894 -5.24947  1.000 46.30977  ? 233 ARG A CG  1 
ATOM   1746 C CD  . ARG A 1 273 ? 0.29142   -12.00947 -4.85286  1.000 56.39687  ? 233 ARG A CD  1 
ATOM   1747 N NE  . ARG A 1 273 ? 1.24363   -11.69354 -5.91193  1.000 70.31139  ? 233 ARG A NE  1 
ATOM   1748 C CZ  . ARG A 1 273 ? 0.96309   -10.95664 -6.97917  1.000 69.46722  ? 233 ARG A CZ  1 
ATOM   1749 N NH1 . ARG A 1 273 ? -0.24342  -10.44870 -7.17187  1.000 60.84386  ? 233 ARG A NH1 1 
ATOM   1750 N NH2 . ARG A 1 273 ? 1.91673   -10.72529 -7.87732  1.000 69.83473  ? 233 ARG A NH2 1 
ATOM   1751 N N   . GLY A 1 274 ? -5.15172  -14.74113 -4.14481  1.000 46.41539  ? 234 GLY A N   1 
ATOM   1752 C CA  . GLY A 1 274 ? -6.12813  -15.32572 -3.25710  1.000 49.78901  ? 234 GLY A CA  1 
ATOM   1753 C C   . GLY A 1 274 ? -6.17723  -16.83548 -3.39294  1.000 51.04136  ? 234 GLY A C   1 
ATOM   1754 O O   . GLY A 1 274 ? -5.80909  -17.40409 -4.42026  1.000 51.96763  ? 234 GLY A O   1 
ATOM   1755 N N   . ILE A 1 275 ? -6.64268  -17.49474 -2.33238  1.000 49.45927  ? 235 ILE A N   1 
ATOM   1756 C CA  . ILE A 1 275 ? -6.71693  -18.94991 -2.30468  1.000 51.67101  ? 235 ILE A CA  1 
ATOM   1757 C C   . ILE A 1 275 ? -7.81132  -19.36971 -1.33206  1.000 51.18023  ? 235 ILE A C   1 
ATOM   1758 O O   . ILE A 1 275 ? -8.25181  -18.59089 -0.48347  1.000 44.55250  ? 235 ILE A O   1 
ATOM   1759 C CB  . ILE A 1 275 ? -5.35394  -19.57365 -1.90951  1.000 52.55617  ? 235 ILE A CB  1 
ATOM   1760 C CG1 . ILE A 1 275 ? -5.27819  -21.04729 -2.31756  1.000 54.24146  ? 235 ILE A CG1 1 
ATOM   1761 C CG2 . ILE A 1 275 ? -5.10169  -19.41548 -0.41810  1.000 44.52070  ? 235 ILE A CG2 1 
ATOM   1762 C CD1 . ILE A 1 275 ? -3.88582  -21.63387 -2.20893  1.000 49.14299  ? 235 ILE A CD1 1 
ATOM   1763 N N   . ALA A 1 276 ? -8.25141  -20.62091 -1.46155  1.000 50.11371  ? 236 ALA A N   1 
ATOM   1764 C CA  . ALA A 1 276 ? -9.23170  -21.21789 -0.56805  1.000 41.89491  ? 236 ALA A CA  1 
ATOM   1765 C C   . ALA A 1 276 ? -8.67960  -22.50943 0.02177   1.000 51.47427  ? 236 ALA A C   1 
ATOM   1766 O O   . ALA A 1 276 ? -7.90185  -23.22312 -0.61938  1.000 56.32224  ? 236 ALA A O   1 
ATOM   1767 C CB  . ALA A 1 276 ? -10.55230 -21.50138 -1.29521  1.000 42.31152  ? 236 ALA A CB  1 
ATOM   1768 N N   . VAL A 1 277 ? -9.07348  -22.79693 1.26014   1.000 44.32419  ? 237 VAL A N   1 
ATOM   1769 C CA  . VAL A 1 277 ? -8.75656  -24.06133 1.91580   1.000 53.84405  ? 237 VAL A CA  1 
ATOM   1770 C C   . VAL A 1 277 ? -10.02982 -24.58583 2.56674   1.000 54.71076  ? 237 VAL A C   1 
ATOM   1771 O O   . VAL A 1 277 ? -10.65815 -23.88033 3.36508   1.000 54.38695  ? 237 VAL A O   1 
ATOM   1772 C CB  . VAL A 1 277 ? -7.63492  -23.91155 2.95884   1.000 54.25993  ? 237 VAL A CB  1 
ATOM   1773 C CG1 . VAL A 1 277 ? -7.41672  -25.22026 3.69247   1.000 53.22047  ? 237 VAL A CG1 1 
ATOM   1774 C CG2 . VAL A 1 277 ? -6.34036  -23.45936 2.29565   1.000 43.45912  ? 237 VAL A CG2 1 
ATOM   1775 N N   . ARG A 1 278 ? -10.40839 -25.81708 2.22897   1.000 58.75764  ? 238 ARG A N   1 
ATOM   1776 C CA  . ARG A 1 278 ? -11.57676 -26.47669 2.80166   1.000 55.11148  ? 238 ARG A CA  1 
ATOM   1777 C C   . ARG A 1 278 ? -11.15159 -27.80112 3.41353   1.000 55.71273  ? 238 ARG A C   1 
ATOM   1778 O O   . ARG A 1 278 ? -10.57576 -28.65268 2.72761   1.000 53.26880  ? 238 ARG A O   1 
ATOM   1779 C CB  . ARG A 1 278 ? -12.67386 -26.70086 1.76029   1.000 50.48494  ? 238 ARG A CB  1 
ATOM   1780 C CG  . ARG A 1 278 ? -13.94018 -27.28445 2.37309   1.000 62.83739  ? 238 ARG A CG  1 
ATOM   1781 C CD  . ARG A 1 278 ? -15.09103 -27.35497 1.38651   1.000 80.80079  ? 238 ARG A CD  1 
ATOM   1782 N NE  . ARG A 1 278 ? -16.28829 -27.91441 2.00422   1.000 89.43207  ? 238 ARG A NE  1 
ATOM   1783 C CZ  . ARG A 1 278 ? -17.24413 -27.20061 2.58275   1.000 94.31028  ? 238 ARG A CZ  1 
ATOM   1784 N NH1 . ARG A 1 278 ? -17.17078 -25.88253 2.66241   1.000 91.76089  ? 238 ARG A NH1 1 
ATOM   1785 N NH2 . ARG A 1 278 ? -18.30146 -27.82581 3.09338   1.000 93.22659  ? 238 ARG A NH2 1 
ATOM   1786 N N   . MET A 1 279 ? -11.43681 -27.96657 4.70043   1.000 50.96263  ? 239 MET A N   1 
ATOM   1787 C CA  . MET A 1 279 ? -11.08466 -29.16062 5.45239   1.000 53.38906  ? 239 MET A CA  1 
ATOM   1788 C C   . MET A 1 279 ? -12.35046 -29.84774 5.94578   1.000 54.08522  ? 239 MET A C   1 
ATOM   1789 O O   . MET A 1 279 ? -13.23743 -29.19372 6.50530   1.000 60.12641  ? 239 MET A O   1 
ATOM   1790 C CB  . MET A 1 279 ? -10.17286 -28.79315 6.62179   1.000 48.56059  ? 239 MET A CB  1 
ATOM   1791 C CG  . MET A 1 279 ? -8.69775  -28.94643 6.30595   1.000 61.53054  ? 239 MET A CG  1 
ATOM   1792 S SD  . MET A 1 279 ? -7.65351  -28.20089 7.56813   1.000 71.22509  ? 239 MET A SD  1 
ATOM   1793 C CE  . MET A 1 279 ? -8.52800  -28.73315 9.03300   1.000 68.40232  ? 239 MET A CE  1 
ATOM   1794 N N   . GLU A 1 280 ? -12.42828 -31.16262 5.75099   1.000 51.27250  ? 240 GLU A N   1 
ATOM   1795 C CA  . GLU A 1 280 ? -13.55755 -31.96124 6.20835   1.000 46.19008  ? 240 GLU A CA  1 
ATOM   1796 C C   . GLU A 1 280 ? -13.06011 -33.07963 7.11038   1.000 48.81854  ? 240 GLU A C   1 
ATOM   1797 O O   . GLU A 1 280 ? -12.01939 -33.68485 6.83825   1.000 54.86816  ? 240 GLU A O   1 
ATOM   1798 C CB  . GLU A 1 280 ? -14.31316 -32.61758 5.04906   1.000 56.15711  ? 240 GLU A CB  1 
ATOM   1799 C CG  . GLU A 1 280 ? -14.69373 -31.75334 3.87246   1.000 55.67358  ? 240 GLU A CG  1 
ATOM   1800 C CD  . GLU A 1 280 ? -15.15441 -32.61353 2.70996   1.000 75.13513  ? 240 GLU A CD  1 
ATOM   1801 O OE1 . GLU A 1 280 ? -15.30780 -33.83856 2.91223   1.000 67.69027  ? 240 GLU A OE1 1 
ATOM   1802 O OE2 . GLU A 1 280 ? -15.35790 -32.07967 1.60205   1.000 94.13589  ? 240 GLU A OE2 1 
ATOM   1803 N N   . ARG A 1 281 ? -13.79658 -33.35698 8.18485   1.000 36.20815  ? 241 ARG A N   1 
ATOM   1804 C CA  . ARG A 1 281 ? -13.56665 -34.57874 8.94595   1.000 47.14464  ? 241 ARG A CA  1 
ATOM   1805 C C   . ARG A 1 281 ? -14.90091 -35.18421 9.35203   1.000 45.99469  ? 241 ARG A C   1 
ATOM   1806 O O   . ARG A 1 281 ? -15.76269 -34.49098 9.90098   1.000 49.04832  ? 241 ARG A O   1 
ATOM   1807 C CB  . ARG A 1 281 ? -12.70194 -34.33671 10.19199  1.000 51.76725  ? 241 ARG A CB  1 
ATOM   1808 C CG  . ARG A 1 281 ? -12.44747 -35.61679 11.00015  1.000 40.20589  ? 241 ARG A CG  1 
ATOM   1809 C CD  . ARG A 1 281 ? -11.39912 -35.43315 12.09388  1.000 43.09887  ? 241 ARG A CD  1 
ATOM   1810 N NE  . ARG A 1 281 ? -11.00886 -36.70260 12.69759  1.000 46.07419  ? 241 ARG A NE  1 
ATOM   1811 C CZ  . ARG A 1 281 ? -10.14700 -37.55363 12.15701  1.000 54.79185  ? 241 ARG A CZ  1 
ATOM   1812 N NH1 . ARG A 1 281 ? -9.56730  -37.30392 10.99501  1.000 46.53178  ? 241 ARG A NH1 1 
ATOM   1813 N NH2 . ARG A 1 281 ? -9.85391  -38.67999 12.80187  1.000 52.54879  ? 241 ARG A NH2 1 
ATOM   1814 N N   . LYS A 1 282 ? -15.05598 -36.47859 9.08790   1.000 51.10848  ? 242 LYS A N   1 
ATOM   1815 C CA  . LYS A 1 282 ? -16.15943 -37.28106 9.59835   1.000 41.91349  ? 242 LYS A CA  1 
ATOM   1816 C C   . LYS A 1 282 ? -15.55019 -38.34413 10.49702  1.000 49.51854  ? 242 LYS A C   1 
ATOM   1817 O O   . LYS A 1 282 ? -14.74829 -39.16226 10.03284  1.000 48.09820  ? 242 LYS A O   1 
ATOM   1818 C CB  . LYS A 1 282 ? -16.95837 -37.91514 8.45755   1.000 32.13242  ? 242 LYS A CB  1 
ATOM   1819 C CG  . LYS A 1 282 ? -18.14738 -38.74266 8.90935   1.000 46.90337  ? 242 LYS A CG  1 
ATOM   1820 C CD  . LYS A 1 282 ? -18.94621 -39.25536 7.71991   1.000 47.64661  ? 242 LYS A CD  1 
ATOM   1821 C CE  . LYS A 1 282 ? -18.12102 -40.21252 6.87835   1.000 47.08122  ? 242 LYS A CE  1 
ATOM   1822 N NZ  . LYS A 1 282 ? -17.66056 -41.37872 7.67737   1.000 53.03712  ? 242 LYS A NZ  1 
ATOM   1823 N N   . GLY A 1 283 ? -15.92314 -38.33985 11.77497  1.000 49.33319  ? 243 GLY A N   1 
ATOM   1824 C CA  . GLY A 1 283 ? -15.21455 -39.19193 12.70336  1.000 45.63336  ? 243 GLY A CA  1 
ATOM   1825 C C   . GLY A 1 283 ? -16.03154 -39.62112 13.90093  1.000 51.33722  ? 243 GLY A C   1 
ATOM   1826 O O   . GLY A 1 283 ? -17.22410 -39.33237 14.00964  1.000 41.41061  ? 243 GLY A O   1 
ATOM   1827 N N   . VAL A 1 284 ? -15.35771 -40.32297 14.80914  1.000 50.67009  ? 244 VAL A N   1 
ATOM   1828 C CA  . VAL A 1 284 ? -15.97369 -40.92399 15.98440  1.000 50.41584  ? 244 VAL A CA  1 
ATOM   1829 C C   . VAL A 1 284 ? -15.49141 -40.17336 17.21755  1.000 47.88038  ? 244 VAL A C   1 
ATOM   1830 O O   . VAL A 1 284 ? -14.28537 -40.12515 17.49247  1.000 45.42362  ? 244 VAL A O   1 
ATOM   1831 C CB  . VAL A 1 284 ? -15.63926 -42.41999 16.08896  1.000 51.67937  ? 244 VAL A CB  1 
ATOM   1832 C CG1 . VAL A 1 284 ? -16.33119 -43.02686 17.29839  1.000 39.41168  ? 244 VAL A CG1 1 
ATOM   1833 C CG2 . VAL A 1 284 ? -16.02462 -43.15307 14.80271  1.000 40.43763  ? 244 VAL A CG2 1 
ATOM   1834 N N   . SER A 1 285 ? -16.43224 -39.60867 17.97240  1.000 52.96762  ? 245 SER A N   1 
ATOM   1835 C CA  . SER A 1 285 ? -16.13444 -38.98771 19.25768  1.000 52.24446  ? 245 SER A CA  1 
ATOM   1836 C C   . SER A 1 285 ? -16.44893 -40.00423 20.34735  1.000 49.76536  ? 245 SER A C   1 
ATOM   1837 O O   . SER A 1 285 ? -17.62058 -40.25753 20.65451  1.000 53.76847  ? 245 SER A O   1 
ATOM   1838 C CB  . SER A 1 285 ? -16.93246 -37.70165 19.45241  1.000 45.58262  ? 245 SER A CB  1 
ATOM   1839 O OG  . SER A 1 285 ? -16.54381 -36.70351 18.52264  1.000 54.73668  ? 245 SER A OG  1 
ATOM   1840 N N   . GLY A 1 286 ? -15.40123 -40.58404 20.92899  1.000 54.48796  ? 246 GLY A N   1 
ATOM   1841 C CA  . GLY A 1 286 ? -15.59304 -41.64513 21.89328  1.000 53.26841  ? 246 GLY A CA  1 
ATOM   1842 C C   . GLY A 1 286 ? -15.95803 -42.92320 21.17305  1.000 50.68764  ? 246 GLY A C   1 
ATOM   1843 O O   . GLY A 1 286 ? -15.09156 -43.64292 20.66901  1.000 55.78867  ? 246 GLY A O   1 
ATOM   1844 N N   . GLN A 1 287 ? -17.25607 -43.21344 21.13084  1.000 54.98748  ? 247 GLN A N   1 
ATOM   1845 C CA  . GLN A 1 287 ? -17.78307 -44.33119 20.36466  1.000 49.80166  ? 247 GLN A CA  1 
ATOM   1846 C C   . GLN A 1 287 ? -18.93970 -43.92564 19.46115  1.000 41.09873  ? 247 GLN A C   1 
ATOM   1847 O O   . GLN A 1 287 ? -19.50790 -44.78994 18.78498  1.000 47.50120  ? 247 GLN A O   1 
ATOM   1848 C CB  . GLN A 1 287 ? -18.23712 -45.45907 21.30331  1.000 40.55537  ? 247 GLN A CB  1 
ATOM   1849 C CG  . GLN A 1 287 ? -17.11922 -46.39770 21.71065  1.000 50.97840  ? 247 GLN A CG  1 
ATOM   1850 C CD  . GLN A 1 287 ? -17.46682 -47.21956 22.92790  1.000 64.55556  ? 247 GLN A CD  1 
ATOM   1851 O OE1 . GLN A 1 287 ? -18.63217 -47.31943 23.30691  1.000 70.49117  ? 247 GLN A OE1 1 
ATOM   1852 N NE2 . GLN A 1 287 ? -16.45563 -47.79727 23.56178  1.000 54.98339  ? 247 GLN A NE2 1 
ATOM   1853 N N   . THR A 1 288 ? -19.28722 -42.64097 19.41175  1.000 40.46592  ? 248 THR A N   1 
ATOM   1854 C CA  . THR A 1 288 ? -20.40961 -42.15934 18.61622  1.000 41.52296  ? 248 THR A CA  1 
ATOM   1855 C C   . THR A 1 288 ? -19.92749 -41.80469 17.21482  1.000 44.65143  ? 248 THR A C   1 
ATOM   1856 O O   . THR A 1 288 ? -19.06492 -40.93568 17.05164  1.000 55.44807  ? 248 THR A O   1 
ATOM   1857 C CB  . THR A 1 288 ? -21.06117 -40.94968 19.28293  1.000 42.72769  ? 248 THR A CB  1 
ATOM   1858 O OG1 . THR A 1 288 ? -21.45093 -41.29318 20.61879  1.000 53.81840  ? 248 THR A OG1 1 
ATOM   1859 C CG2 . THR A 1 288 ? -22.28618 -40.50858 18.49761  1.000 44.93166  ? 248 THR A CG2 1 
ATOM   1860 N N   . GLN A 1 289 ? -20.49189 -42.46895 16.21078  1.000 50.21849  ? 249 GLN A N   1 
ATOM   1861 C CA  . GLN A 1 289 ? -20.07685 -42.28041 14.83169  1.000 40.82418  ? 249 GLN A CA  1 
ATOM   1862 C C   . GLN A 1 289 ? -20.63304 -40.97642 14.26009  1.000 46.73097  ? 249 GLN A C   1 
ATOM   1863 O O   . GLN A 1 289 ? -21.47496 -40.30201 14.86092  1.000 47.52267  ? 249 GLN A O   1 
ATOM   1864 C CB  . GLN A 1 289 ? -20.53846 -43.45776 13.97274  1.000 42.56238  ? 249 GLN A CB  1 
ATOM   1865 C CG  . GLN A 1 289 ? -20.41218 -44.81266 14.65397  1.000 38.85122  ? 249 GLN A CG  1 
ATOM   1866 C CD  . GLN A 1 289 ? -18.97002 -45.24247 14.86036  1.000 49.67066  ? 249 GLN A CD  1 
ATOM   1867 O OE1 . GLN A 1 289 ? -18.26592 -45.58225 13.90882  1.000 43.81632  ? 249 GLN A OE1 1 
ATOM   1868 N NE2 . GLN A 1 289 ? -18.52789 -45.23972 16.11251  1.000 36.80799  ? 249 GLN A NE2 1 
ATOM   1869 N N   . ASN A 1 290 ? -20.12742 -40.62121 13.07685  1.000 48.59839  ? 250 ASN A N   1 
ATOM   1870 C CA  . ASN A 1 290 ? -20.74570 -39.61468 12.21167  1.000 46.87838  ? 250 ASN A CA  1 
ATOM   1871 C C   . ASN A 1 290 ? -20.70205 -38.21339 12.82588  1.000 50.42631  ? 250 ASN A C   1 
ATOM   1872 O O   . ASN A 1 290 ? -21.65772 -37.44343 12.71773  1.000 42.00004  ? 250 ASN A O   1 
ATOM   1873 C CB  . ASN A 1 290 ? -22.18289 -40.00690 11.85722  1.000 36.56754  ? 250 ASN A CB  1 
ATOM   1874 C CG  . ASN A 1 290 ? -22.68860 -39.30431 10.61772  1.000 46.64010  ? 250 ASN A CG  1 
ATOM   1875 O OD1 . ASN A 1 290 ? -21.95583 -39.14461 9.64197   1.000 52.82778  ? 250 ASN A OD1 1 
ATOM   1876 N ND2 . ASN A 1 290 ? -23.94733 -38.88118 10.64640  1.000 44.06836  ? 250 ASN A ND2 1 
ATOM   1877 N N   . GLN A 1 291 ? -19.59223 -37.87612 13.47594  1.000 48.48529  ? 251 GLN A N   1 
ATOM   1878 C CA  . GLN A 1 291 ? -19.35872 -36.49835 13.88412  1.000 43.16490  ? 251 GLN A CA  1 
ATOM   1879 C C   . GLN A 1 291 ? -18.78191 -35.72464 12.70526  1.000 47.95429  ? 251 GLN A C   1 
ATOM   1880 O O   . GLN A 1 291 ? -17.79343 -36.14807 12.09874  1.000 51.38179  ? 251 GLN A O   1 
ATOM   1881 C CB  . GLN A 1 291 ? -18.41873 -36.44029 15.08670  1.000 46.58459  ? 251 GLN A CB  1 
ATOM   1882 C CG  . GLN A 1 291 ? -18.90411 -37.22563 16.29753  1.000 55.80579  ? 251 GLN A CG  1 
ATOM   1883 C CD  . GLN A 1 291 ? -20.08477 -36.56658 16.99628  1.000 55.38156  ? 251 GLN A CD  1 
ATOM   1884 O OE1 . GLN A 1 291 ? -21.23435 -36.72035 16.58201  1.000 59.19340  ? 251 GLN A OE1 1 
ATOM   1885 N NE2 . GLN A 1 291 ? -19.80356 -35.83676 18.06846  1.000 50.07948  ? 251 GLN A NE2 1 
ATOM   1886 N N   . LEU A 1 292 ? -19.38983 -34.58318 12.39262  1.000 44.68151  ? 252 LEU A N   1 
ATOM   1887 C CA  . LEU A 1 292 ? -19.14246 -33.87147 11.14605  1.000 41.21940  ? 252 LEU A CA  1 
ATOM   1888 C C   . LEU A 1 292 ? -18.49407 -32.52665 11.44002  1.000 50.12510  ? 252 LEU A C   1 
ATOM   1889 O O   . LEU A 1 292 ? -19.00270 -31.75232 12.25790  1.000 49.51974  ? 252 LEU A O   1 
ATOM   1890 C CB  . LEU A 1 292 ? -20.44823 -33.66303 10.37543  1.000 44.70396  ? 252 LEU A CB  1 
ATOM   1891 C CG  . LEU A 1 292 ? -21.27385 -34.92765 10.13166  1.000 50.67532  ? 252 LEU A CG  1 
ATOM   1892 C CD1 . LEU A 1 292 ? -22.55466 -34.60065 9.38447   1.000 56.20092  ? 252 LEU A CD1 1 
ATOM   1893 C CD2 . LEU A 1 292 ? -20.45849 -35.96328 9.38008   1.000 42.36221  ? 252 LEU A CD2 1 
ATOM   1894 N N   . PHE A 1 293 ? -17.37748 -32.25037 10.76807  1.000 50.90392  ? 253 PHE A N   1 
ATOM   1895 C CA  . PHE A 1 293 ? -16.62666 -31.01999 10.97096  1.000 48.27905  ? 253 PHE A CA  1 
ATOM   1896 C C   . PHE A 1 293 ? -16.23277 -30.44458 9.62052   1.000 41.04292  ? 253 PHE A C   1 
ATOM   1897 O O   . PHE A 1 293 ? -15.77549 -31.17487 8.73631   1.000 46.23703  ? 253 PHE A O   1 
ATOM   1898 C CB  . PHE A 1 293 ? -15.36093 -31.25133 11.80712  1.000 35.79410  ? 253 PHE A CB  1 
ATOM   1899 C CG  . PHE A 1 293 ? -15.58409 -32.07048 13.04148  1.000 50.78112  ? 253 PHE A CG  1 
ATOM   1900 C CD1 . PHE A 1 293 ? -15.59605 -33.45608 12.97872  1.000 42.64031  ? 253 PHE A CD1 1 
ATOM   1901 C CD2 . PHE A 1 293 ? -15.77340 -31.45850 14.26637  1.000 41.09259  ? 253 PHE A CD2 1 
ATOM   1902 C CE1 . PHE A 1 293 ? -15.79665 -34.21259 14.11407  1.000 47.31377  ? 253 PHE A CE1 1 
ATOM   1903 C CE2 . PHE A 1 293 ? -15.97294 -32.21233 15.40678  1.000 42.27653  ? 253 PHE A CE2 1 
ATOM   1904 C CZ  . PHE A 1 293 ? -15.98582 -33.58848 15.33000  1.000 52.70878  ? 253 PHE A CZ  1 
ATOM   1905 N N   . THR A 1 294 ? -16.41142 -29.13515 9.46698   1.000 39.11866  ? 254 THR A N   1 
ATOM   1906 C CA  . THR A 1 294 ? -16.03476 -28.44487 8.24179   1.000 40.79166  ? 254 THR A CA  1 
ATOM   1907 C C   . THR A 1 294 ? -15.36960 -27.12520 8.58849   1.000 44.19202  ? 254 THR A C   1 
ATOM   1908 O O   . THR A 1 294 ? -15.88910 -26.36308 9.40976   1.000 45.33689  ? 254 THR A O   1 
ATOM   1909 C CB  . THR A 1 294 ? -17.24604 -28.19198 7.33938   1.000 43.37399  ? 254 THR A CB  1 
ATOM   1910 O OG1 . THR A 1 294 ? -17.95747 -29.41797 7.13235   1.000 61.88621  ? 254 THR A OG1 1 
ATOM   1911 C CG2 . THR A 1 294 ? -16.78836 -27.65468 6.00557   1.000 53.44618  ? 254 THR A CG2 1 
ATOM   1912 N N   . TYR A 1 295 ? -14.22720 -26.85793 7.95976   1.000 49.12993  ? 255 TYR A N   1 
ATOM   1913 C CA  . TYR A 1 295 ? -13.53224 -25.59055 8.12513   1.000 47.13402  ? 255 TYR A CA  1 
ATOM   1914 C C   . TYR A 1 295 ? -13.18457 -25.03073 6.75408   1.000 50.06352  ? 255 TYR A C   1 
ATOM   1915 O O   . TYR A 1 295 ? -12.69022 -25.76089 5.88810   1.000 54.29605  ? 255 TYR A O   1 
ATOM   1916 C CB  . TYR A 1 295 ? -12.26453 -25.73918 8.96991   1.000 49.20651  ? 255 TYR A CB  1 
ATOM   1917 C CG  . TYR A 1 295 ? -11.51179 -24.43822 9.08326   1.000 51.80222  ? 255 TYR A CG  1 
ATOM   1918 C CD1 . TYR A 1 295 ? -11.92539 -23.46030 9.97658   1.000 52.80176  ? 255 TYR A CD1 1 
ATOM   1919 C CD2 . TYR A 1 295 ? -10.41017 -24.17239 8.28437   1.000 47.20239  ? 255 TYR A CD2 1 
ATOM   1920 C CE1 . TYR A 1 295 ? -11.25668 -22.26006 10.08169  1.000 50.21669  ? 255 TYR A CE1 1 
ATOM   1921 C CE2 . TYR A 1 295 ? -9.73666  -22.97539 8.38288   1.000 54.96668  ? 255 TYR A CE2 1 
ATOM   1922 C CZ  . TYR A 1 295 ? -10.16165 -22.02149 9.28335   1.000 58.61685  ? 255 TYR A CZ  1 
ATOM   1923 O OH  . TYR A 1 295 ? -9.49231  -20.82382 9.38730   1.000 56.93375  ? 255 TYR A OH  1 
ATOM   1924 N N   . GLU A 1 296 ? -13.43788 -23.73707 6.56351   1.000 49.33464  ? 256 GLU A N   1 
ATOM   1925 C CA  . GLU A 1 296 ? -13.24937 -23.08821 5.27489   1.000 53.04678  ? 256 GLU A CA  1 
ATOM   1926 C C   . GLU A 1 296 ? -12.71501 -21.67829 5.47059   1.000 55.73637  ? 256 GLU A C   1 
ATOM   1927 O O   . GLU A 1 296 ? -13.13879 -20.96764 6.38665   1.000 51.00714  ? 256 GLU A O   1 
ATOM   1928 C CB  . GLU A 1 296 ? -14.56321 -23.02482 4.48482   1.000 49.12758  ? 256 GLU A CB  1 
ATOM   1929 C CG  . GLU A 1 296 ? -14.61244 -23.91873 3.26373   1.000 68.19434  ? 256 GLU A CG  1 
ATOM   1930 C CD  . GLU A 1 296 ? -14.72978 -23.13828 1.96777   1.000 84.83722  ? 256 GLU A CD  1 
ATOM   1931 O OE1 . GLU A 1 296 ? -14.99166 -21.91982 2.02403   1.000 89.04346  ? 256 GLU A OE1 1 
ATOM   1932 O OE2 . GLU A 1 296 ? -14.57436 -23.74858 0.89021   1.000 89.77550  ? 256 GLU A OE2 1 
ATOM   1933 N N   . MET A 1 297 ? -11.78400 -21.27792 4.60486   1.000 49.56907  ? 257 MET A N   1 
ATOM   1934 C CA  . MET A 1 297 ? -11.29451 -19.90738 4.59009   1.000 50.50605  ? 257 MET A CA  1 
ATOM   1935 C C   . MET A 1 297 ? -11.03052 -19.46947 3.15816   1.000 49.05970  ? 257 MET A C   1 
ATOM   1936 O O   . MET A 1 297 ? -10.50140 -20.23525 2.34745   1.000 42.79175  ? 257 MET A O   1 
ATOM   1937 C CB  . MET A 1 297 ? -10.00498 -19.69645 5.39899   1.000 40.37245  ? 257 MET A CB  1 
ATOM   1938 C CG  . MET A 1 297 ? -8.86533  -20.66026 5.13201   1.000 47.78279  ? 257 MET A CG  1 
ATOM   1939 S SD  . MET A 1 297 ? -7.39716  -20.01954 5.97163   1.000 74.11474  ? 257 MET A SD  1 
ATOM   1940 C CE  . MET A 1 297 ? -7.17311  -21.15793 7.31782   1.000 53.53965  ? 257 MET A CE  1 
ATOM   1941 N N   . ARG A 1 298 ? -11.39530 -18.22382 2.86464   1.000 52.78688  ? 258 ARG A N   1 
ATOM   1942 C CA  . ARG A 1 298 ? -11.14302 -17.59241 1.57356   1.000 56.04314  ? 258 ARG A CA  1 
ATOM   1943 C C   . ARG A 1 298 ? -10.40694 -16.29470 1.86651   1.000 48.35019  ? 258 ARG A C   1 
ATOM   1944 O O   . ARG A 1 298 ? -11.00715 -15.33079 2.35332   1.000 62.58502  ? 258 ARG A O   1 
ATOM   1945 C CB  . ARG A 1 298 ? -12.44303 -17.34910 0.80656   1.000 54.05254  ? 258 ARG A CB  1 
ATOM   1946 C CG  . ARG A 1 298 ? -13.22277 -18.62481 0.55943   1.000 52.19169  ? 258 ARG A CG  1 
ATOM   1947 C CD  . ARG A 1 298 ? -14.37915 -18.41754 -0.39350  1.000 68.42951  ? 258 ARG A CD  1 
ATOM   1948 N NE  . ARG A 1 298 ? -15.17430 -19.63227 -0.51776  1.000 84.73866  ? 258 ARG A NE  1 
ATOM   1949 C CZ  . ARG A 1 298 ? -14.92671 -20.59732 -1.39267  1.000 88.22461  ? 258 ARG A CZ  1 
ATOM   1950 N NH1 . ARG A 1 298 ? -13.92472 -20.50973 -2.25239  1.000 86.57022  ? 258 ARG A NH1 1 
ATOM   1951 N NH2 . ARG A 1 298 ? -15.70288 -21.67728 -1.40494  1.000 85.97500  ? 258 ARG A NH2 1 
ATOM   1952 N N   . ILE A 1 299 ? -9.10655  -16.27378 1.57814   1.000 47.73486  ? 259 ILE A N   1 
ATOM   1953 C CA  . ILE A 1 299 ? -8.20859  -15.26431 2.11781   1.000 48.28574  ? 259 ILE A CA  1 
ATOM   1954 C C   . ILE A 1 299 ? -7.16355  -14.86452 1.08705   1.000 47.48319  ? 259 ILE A C   1 
ATOM   1955 O O   . ILE A 1 299 ? -6.88412  -15.58718 0.12748   1.000 46.19663  ? 259 ILE A O   1 
ATOM   1956 C CB  . ILE A 1 299 ? -7.51462  -15.76927 3.40361   1.000 53.05285  ? 259 ILE A CB  1 
ATOM   1957 C CG1 . ILE A 1 299 ? -7.06636  -17.22615 3.23408   1.000 55.70798  ? 259 ILE A CG1 1 
ATOM   1958 C CG2 . ILE A 1 299 ? -8.44336  -15.63413 4.60405   1.000 51.70273  ? 259 ILE A CG2 1 
ATOM   1959 C CD1 . ILE A 1 299 ? -5.70618  -17.40732 2.58217   1.000 54.71842  ? 259 ILE A CD1 1 
ATOM   1960 N N   . ASN A 1 300 ? -6.58080  -13.69090 1.31181   1.000 51.92669  ? 260 ASN A N   1 
ATOM   1961 C CA  . ASN A 1 300 ? -5.36458  -13.29106 0.61690   1.000 47.59143  ? 260 ASN A CA  1 
ATOM   1962 C C   . ASN A 1 300 ? -4.19654  -14.10356 1.16903   1.000 45.50020  ? 260 ASN A C   1 
ATOM   1963 O O   . ASN A 1 300 ? -3.86363  -13.99298 2.35493   1.000 45.93999  ? 260 ASN A O   1 
ATOM   1964 C CB  . ASN A 1 300 ? -5.14099  -11.78849 0.79807   1.000 45.36317  ? 260 ASN A CB  1 
ATOM   1965 C CG  . ASN A 1 300 ? -3.89889  -11.27055 0.07951   1.000 50.65601  ? 260 ASN A CG  1 
ATOM   1966 O OD1 . ASN A 1 300 ? -2.83582  -11.88727 0.10900   1.000 51.40818  ? 260 ASN A OD1 1 
ATOM   1967 N ND2 . ASN A 1 300 ? -4.03914  -10.12642 -0.57757  1.000 43.37687  ? 260 ASN A ND2 1 
ATOM   1968 N N   . ASN A 1 301 ? -3.57992  -14.92942 0.31198   1.000 47.60752  ? 261 ASN A N   1 
ATOM   1969 C CA  . ASN A 1 301 ? -2.57749  -15.88394 0.78018   1.000 50.60833  ? 261 ASN A CA  1 
ATOM   1970 C C   . ASN A 1 301 ? -1.39408  -15.20916 1.46898   1.000 43.55281  ? 261 ASN A C   1 
ATOM   1971 O O   . ASN A 1 301 ? -1.14089  -15.50810 2.65085   1.000 48.54491  ? 261 ASN A O   1 
ATOM   1972 C CB  . ASN A 1 301 ? -2.14833  -16.78230 -0.38904  1.000 49.28059  ? 261 ASN A CB  1 
ATOM   1973 C CG  . ASN A 1 301 ? -1.26759  -17.94653 0.04363   1.000 54.99143  ? 261 ASN A CG  1 
ATOM   1974 O OD1 . ASN A 1 301 ? -0.73044  -17.96979 1.15220   1.000 48.85708  ? 261 ASN A OD1 1 
ATOM   1975 N ND2 . ASN A 1 301 ? -1.10828  -18.91853 -0.84567  1.000 66.60263  ? 261 ASN A ND2 1 
ATOM   1976 N N   . PRO A 1 302 ? -0.62629  -14.31763 0.82135   1.000 42.91368  ? 262 PRO A N   1 
ATOM   1977 C CA  . PRO A 1 302 ? 0.49509   -13.69269 1.54758   1.000 48.76304  ? 262 PRO A CA  1 
ATOM   1978 C C   . PRO A 1 302 ? 0.06192   -12.82096 2.71500   1.000 46.78213  ? 262 PRO A C   1 
ATOM   1979 O O   . PRO A 1 302 ? 0.74934   -12.79291 3.74347   1.000 52.89351  ? 262 PRO A O   1 
ATOM   1980 C CB  . PRO A 1 302 ? 1.21003   -12.87471 0.46148   1.000 43.36140  ? 262 PRO A CB  1 
ATOM   1981 C CG  . PRO A 1 302 ? 0.20047   -12.67349 -0.59803  1.000 50.51649  ? 262 PRO A CG  1 
ATOM   1982 C CD  . PRO A 1 302 ? -0.64258  -13.90041 -0.59419  1.000 45.92897  ? 262 PRO A CD  1 
ATOM   1983 N N   . ALA A 1 303 ? -1.04952  -12.09247 2.57865   1.000 47.41875  ? 263 ALA A N   1 
ATOM   1984 C CA  . ALA A 1 303 ? -1.53572  -11.26118 3.67713   1.000 51.12424  ? 263 ALA A CA  1 
ATOM   1985 C C   . ALA A 1 303 ? -1.78721  -12.09289 4.92767   1.000 53.49794  ? 263 ALA A C   1 
ATOM   1986 O O   . ALA A 1 303 ? -1.38737  -11.71282 6.03445   1.000 50.74803  ? 263 ALA A O   1 
ATOM   1987 C CB  . ALA A 1 303 ? -2.80846  -10.52707 3.25681   1.000 44.21308  ? 263 ALA A CB  1 
ATOM   1988 N N   . LEU A 1 304 ? -2.46564  -13.22938 4.76950   1.000 50.99163  ? 264 LEU A N   1 
ATOM   1989 C CA  . LEU A 1 304 ? -2.75489  -14.08653 5.91230   1.000 45.36463  ? 264 LEU A CA  1 
ATOM   1990 C C   . LEU A 1 304 ? -1.48366  -14.73189 6.44897   1.000 49.77182  ? 264 LEU A C   1 
ATOM   1991 O O   . LEU A 1 304 ? -1.24910  -14.74850 7.66321   1.000 40.54503  ? 264 LEU A O   1 
ATOM   1992 C CB  . LEU A 1 304 ? -3.77615  -15.15051 5.51970   1.000 56.33276  ? 264 LEU A CB  1 
ATOM   1993 C CG  . LEU A 1 304 ? -4.16943  -16.08775 6.65553   1.000 48.75592  ? 264 LEU A CG  1 
ATOM   1994 C CD1 . LEU A 1 304 ? -5.09753  -15.36217 7.61094   1.000 54.03587  ? 264 LEU A CD1 1 
ATOM   1995 C CD2 . LEU A 1 304 ? -4.81602  -17.33851 6.09760   1.000 57.16883  ? 264 LEU A CD2 1 
ATOM   1996 N N   . THR A 1 305 ? -0.65783  -15.28303 5.55387   1.000 49.73001  ? 265 THR A N   1 
ATOM   1997 C CA  . THR A 1 305 ? 0.57139   -15.94780 5.97789   1.000 45.38506  ? 265 THR A CA  1 
ATOM   1998 C C   . THR A 1 305 ? 1.47825   -15.00145 6.75496   1.000 47.68091  ? 265 THR A C   1 
ATOM   1999 O O   . THR A 1 305 ? 2.03662   -15.37795 7.79229   1.000 53.63358  ? 265 THR A O   1 
ATOM   2000 C CB  . THR A 1 305 ? 1.31142   -16.51122 4.76345   1.000 53.06999  ? 265 THR A CB  1 
ATOM   2001 O OG1 . THR A 1 305 ? 0.47698   -17.46087 4.08859   1.000 47.02400  ? 265 THR A OG1 1 
ATOM   2002 C CG2 . THR A 1 305 ? 2.61358   -17.18972 5.19323   1.000 44.77156  ? 265 THR A CG2 1 
ATOM   2003 N N   . SER A 1 306 ? 1.63565   -13.76784 6.27056   1.000 41.75119  ? 266 SER A N   1 
ATOM   2004 C CA  . SER A 1 306 ? 2.47152   -12.80032 6.97373   1.000 46.52672  ? 266 SER A CA  1 
ATOM   2005 C C   . SER A 1 306 ? 1.87453   -12.43567 8.32551   1.000 46.74439  ? 266 SER A C   1 
ATOM   2006 O O   . SER A 1 306 ? 2.60812   -12.19885 9.29209   1.000 45.09811  ? 266 SER A O   1 
ATOM   2007 C CB  . SER A 1 306 ? 2.65631   -11.54952 6.11958   1.000 42.26176  ? 266 SER A CB  1 
ATOM   2008 O OG  . SER A 1 306 ? 1.40836   -10.93372 5.86240   1.000 58.11510  ? 266 SER A OG  1 
ATOM   2009 N N   . GLN A 1 307 ? 0.54540   -12.37121 8.40705   1.000 43.72338  ? 267 GLN A N   1 
ATOM   2010 C CA  . GLN A 1 307 ? -0.10469  -12.06657 9.67547   1.000 40.84794  ? 267 GLN A CA  1 
ATOM   2011 C C   . GLN A 1 307 ? 0.13945   -13.17348 10.69487  1.000 42.88742  ? 267 GLN A C   1 
ATOM   2012 O O   . GLN A 1 307 ? 0.39003   -12.89671 11.87380  1.000 43.26099  ? 267 GLN A O   1 
ATOM   2013 C CB  . GLN A 1 307 ? -1.60040  -11.85237 9.44819   1.000 39.05734  ? 267 GLN A CB  1 
ATOM   2014 C CG  . GLN A 1 307 ? -2.41563  -11.65127 10.71142  1.000 37.94734  ? 267 GLN A CG  1 
ATOM   2015 C CD  . GLN A 1 307 ? -2.09157  -10.34882 11.41693  1.000 42.33323  ? 267 GLN A CD  1 
ATOM   2016 O OE1 . GLN A 1 307 ? -2.71003  -9.31805  11.14893  1.000 53.10007  ? 267 GLN A OE1 1 
ATOM   2017 N NE2 . GLN A 1 307 ? -1.13184  -10.39014 12.33373  1.000 50.47029  ? 267 GLN A NE2 1 
ATOM   2018 N N   . VAL A 1 308 ? 0.05973   -14.43272 10.25942  1.000 42.49442  ? 268 VAL A N   1 
ATOM   2019 C CA  . VAL A 1 308 ? 0.33713   -15.55443 11.15215  1.000 46.23700  ? 268 VAL A CA  1 
ATOM   2020 C C   . VAL A 1 308 ? 1.78286   -15.50703 11.62994  1.000 48.85560  ? 268 VAL A C   1 
ATOM   2021 O O   . VAL A 1 308 ? 2.07546   -15.76861 12.80375  1.000 41.47037  ? 268 VAL A O   1 
ATOM   2022 C CB  . VAL A 1 308 ? 0.01482   -16.88526 10.44588  1.000 46.12471  ? 268 VAL A CB  1 
ATOM   2023 C CG1 . VAL A 1 308 ? 0.53236   -18.06141 11.25553  1.000 47.31499  ? 268 VAL A CG1 1 
ATOM   2024 C CG2 . VAL A 1 308 ? -1.48065  -17.01002 10.21014  1.000 48.28778  ? 268 VAL A CG2 1 
ATOM   2025 N N   . MET A 1 309 ? 2.70943   -15.17365 10.72695  1.000 47.55486  ? 269 MET A N   1 
ATOM   2026 C CA  . MET A 1 309 ? 4.11578   -15.07529 11.10389  1.000 41.41101  ? 269 MET A CA  1 
ATOM   2027 C C   . MET A 1 309 ? 4.33861   -13.95800 12.11639  1.000 48.48999  ? 269 MET A C   1 
ATOM   2028 O O   . MET A 1 309 ? 5.16968   -14.08880 13.02260  1.000 49.18502  ? 269 MET A O   1 
ATOM   2029 C CB  . MET A 1 309 ? 4.97334   -14.85594 9.85784   1.000 40.76586  ? 269 MET A CB  1 
ATOM   2030 C CG  . MET A 1 309 ? 4.94677   -16.02589 8.88956   1.000 46.67492  ? 269 MET A CG  1 
ATOM   2031 S SD  . MET A 1 309 ? 5.81160   -15.69722 7.34299   1.000 58.90675  ? 269 MET A SD  1 
ATOM   2032 C CE  . MET A 1 309 ? 7.50892   -15.92269 7.85454   1.000 55.42578  ? 269 MET A CE  1 
ATOM   2033 N N   . ILE A 1 310 ? 3.60398   -12.85064 11.98001  1.000 45.86712  ? 270 ILE A N   1 
ATOM   2034 C CA  . ILE A 1 310 ? 3.71487   -11.76153 12.94615  1.000 45.98925  ? 270 ILE A CA  1 
ATOM   2035 C C   . ILE A 1 310 ? 3.12470   -12.17910 14.28667  1.000 49.37557  ? 270 ILE A C   1 
ATOM   2036 O O   . ILE A 1 310 ? 3.69511   -11.89641 15.34714  1.000 48.43714  ? 270 ILE A O   1 
ATOM   2037 C CB  . ILE A 1 310 ? 3.04542   -10.48810 12.39351  1.000 49.83373  ? 270 ILE A CB  1 
ATOM   2038 C CG1 . ILE A 1 310 ? 4.07897   -9.59498  11.70126  1.000 47.58842  ? 270 ILE A CG1 1 
ATOM   2039 C CG2 . ILE A 1 310 ? 2.34011   -9.70897  13.50055  1.000 40.84147  ? 270 ILE A CG2 1 
ATOM   2040 C CD1 . ILE A 1 310 ? 4.82371   -10.24810 10.55384  1.000 37.74083  ? 270 ILE A CD1 1 
ATOM   2041 N N   . ALA A 1 311 ? 1.97767   -12.86259 14.26282  1.000 51.11029  ? 271 ALA A N   1 
ATOM   2042 C CA  . ALA A 1 311 ? 1.40089   -13.37820 15.49914  1.000 42.16597  ? 271 ALA A CA  1 
ATOM   2043 C C   . ALA A 1 311 ? 2.32654   -14.39471 16.15172  1.000 47.50074  ? 271 ALA A C   1 
ATOM   2044 O O   . ALA A 1 311 ? 2.42757   -14.45529 17.38289  1.000 46.13253  ? 271 ALA A O   1 
ATOM   2045 C CB  . ALA A 1 311 ? 0.03002   -13.99197 15.22006  1.000 44.82827  ? 271 ALA A CB  1 
ATOM   2046 N N   . SER A 1 312 ? 3.01359   -15.20085 15.33944  1.000 45.31107  ? 272 SER A N   1 
ATOM   2047 C CA  . SER A 1 312 ? 3.97666   -16.15105 15.88178  1.000 51.43051  ? 272 SER A CA  1 
ATOM   2048 C C   . SER A 1 312 ? 5.18776   -15.44038 16.47482  1.000 48.75134  ? 272 SER A C   1 
ATOM   2049 O O   . SER A 1 312 ? 5.75081   -15.90786 17.47122  1.000 49.42067  ? 272 SER A O   1 
ATOM   2050 C CB  . SER A 1 312 ? 4.41175   -17.13732 14.79652  1.000 55.36586  ? 272 SER A CB  1 
ATOM   2051 O OG  . SER A 1 312 ? 3.31903   -17.92686 14.35682  1.000 45.18139  ? 272 SER A OG  1 
ATOM   2052 N N   . ALA A 1 313 ? 5.60565   -14.31936 15.87780  1.000 46.74693  ? 273 ALA A N   1 
ATOM   2053 C CA  . ALA A 1 313 ? 6.68628   -13.52692 16.45922  1.000 46.86006  ? 273 ALA A CA  1 
ATOM   2054 C C   . ALA A 1 313 ? 6.33909   -13.08954 17.87420  1.000 47.47632  ? 273 ALA A C   1 
ATOM   2055 O O   . ALA A 1 313 ? 7.19924   -13.08480 18.76215  1.000 49.07688  ? 273 ALA A O   1 
ATOM   2056 C CB  . ALA A 1 313 ? 6.98153   -12.31213 15.58127  1.000 35.87915  ? 273 ALA A CB  1 
ATOM   2057 N N   . ARG A 1 314 ? 5.08280   -12.69930 18.09405  1.000 51.53731  ? 274 ARG A N   1 
ATOM   2058 C CA  . ARG A 1 314 ? 4.61510   -12.40048 19.44166  1.000 47.01385  ? 274 ARG A CA  1 
ATOM   2059 C C   . ARG A 1 314 ? 4.74650   -13.61845 20.34743  1.000 48.22724  ? 274 ARG A C   1 
ATOM   2060 O O   . ARG A 1 314 ? 5.17056   -13.50086 21.50347  1.000 51.92015  ? 274 ARG A O   1 
ATOM   2061 C CB  . ARG A 1 314 ? 3.16715   -11.91732 19.38383  1.000 48.96495  ? 274 ARG A CB  1 
ATOM   2062 C CG  . ARG A 1 314 ? 2.56502   -11.56050 20.72579  1.000 54.51006  ? 274 ARG A CG  1 
ATOM   2063 C CD  . ARG A 1 314 ? 1.11484   -11.12459 20.57235  1.000 54.35281  ? 274 ARG A CD  1 
ATOM   2064 N NE  . ARG A 1 314 ? 0.98637   -9.94751  19.71977  1.000 61.73936  ? 274 ARG A NE  1 
ATOM   2065 C CZ  . ARG A 1 314 ? 0.39776   -9.93832  18.53072  1.000 50.16209  ? 274 ARG A CZ  1 
ATOM   2066 N NH1 . ARG A 1 314 ? -0.17090  -11.02355 18.03099  1.000 47.89070  ? 274 ARG A NH1 1 
ATOM   2067 N NH2 . ARG A 1 314 ? 0.37329   -8.80962  17.82799  1.000 46.10886  ? 274 ARG A NH2 1 
ATOM   2068 N N   . ALA A 1 315 ? 4.36718   -14.79685 19.84234  1.000 52.14695  ? 275 ALA A N   1 
ATOM   2069 C CA  . ALA A 1 315 ? 4.45793   -16.01797 20.63620  1.000 46.69132  ? 275 ALA A CA  1 
ATOM   2070 C C   . ALA A 1 315 ? 5.90376   -16.41479 20.90799  1.000 57.17994  ? 275 ALA A C   1 
ATOM   2071 O O   . ALA A 1 315 ? 6.19978   -16.97238 21.97076  1.000 52.42813  ? 275 ALA A O   1 
ATOM   2072 C CB  . ALA A 1 315 ? 3.72362   -17.15833 19.93356  1.000 45.96858  ? 275 ALA A CB  1 
ATOM   2073 N N   . ALA A 1 316 ? 6.81005   -16.15299 19.96112  1.000 52.95053  ? 276 ALA A N   1 
ATOM   2074 C CA  . ALA A 1 316 ? 8.20987   -16.52583 20.14757  1.000 48.19612  ? 276 ALA A CA  1 
ATOM   2075 C C   . ALA A 1 316 ? 8.80804   -15.84770 21.37472  1.000 52.91922  ? 276 ALA A C   1 
ATOM   2076 O O   . ALA A 1 316 ? 9.63306   -16.44051 22.07945  1.000 59.75335  ? 276 ALA A O   1 
ATOM   2077 C CB  . ALA A 1 316 ? 9.01826   -16.18392 18.89492  1.000 46.65403  ? 276 ALA A CB  1 
ATOM   2078 N N   . MET A 1 317 ? 8.40599   -14.60308 21.64587  1.000 55.37113  ? 277 MET A N   1 
ATOM   2079 C CA  . MET A 1 317 ? 8.90045   -13.87090 22.80744  1.000 44.57406  ? 277 MET A CA  1 
ATOM   2080 C C   . MET A 1 317 ? 8.43995   -14.46440 24.13306  1.000 51.59795  ? 277 MET A C   1 
ATOM   2081 O O   . MET A 1 317 ? 8.92056   -14.02713 25.18400  1.000 62.61999  ? 277 MET A O   1 
ATOM   2082 C CB  . MET A 1 317 ? 8.46418   -12.40548 22.73088  1.000 44.39631  ? 277 MET A CB  1 
ATOM   2083 C CG  . MET A 1 317 ? 9.00323   -11.64375 21.53273  1.000 49.04095  ? 277 MET A CG  1 
ATOM   2084 S SD  . MET A 1 317 ? 10.80267  -11.50128 21.55270  1.000 55.02110  ? 277 MET A SD  1 
ATOM   2085 C CE  . MET A 1 317 ? 11.03231  -10.39171 22.93929  1.000 30.28997  ? 277 MET A CE  1 
ATOM   2086 N N   . ARG A 1 318 ? 7.52492   -15.43269 24.11667  1.000 46.23942  ? 278 ARG A N   1 
ATOM   2087 C CA  . ARG A 1 318 ? 6.95964   -15.99611 25.33584  1.000 48.83577  ? 278 ARG A CA  1 
ATOM   2088 C C   . ARG A 1 318 ? 7.34012   -17.45262 25.56488  1.000 47.51978  ? 278 ARG A C   1 
ATOM   2089 O O   . ARG A 1 318 ? 6.79007   -18.08765 26.46738  1.000 57.28813  ? 278 ARG A O   1 
ATOM   2090 C CB  . ARG A 1 318 ? 5.43853   -15.86088 25.31227  1.000 45.66262  ? 278 ARG A CB  1 
ATOM   2091 C CG  . ARG A 1 318 ? 4.96627   -14.43660 25.16828  1.000 53.96440  ? 278 ARG A CG  1 
ATOM   2092 C CD  . ARG A 1 318 ? 3.49731   -14.37601 24.83413  1.000 51.00224  ? 278 ARG A CD  1 
ATOM   2093 N NE  . ARG A 1 318 ? 2.96645   -13.04190 25.07436  1.000 56.23394  ? 278 ARG A NE  1 
ATOM   2094 C CZ  . ARG A 1 318 ? 1.88526   -12.55177 24.48749  1.000 58.34171  ? 278 ARG A CZ  1 
ATOM   2095 N NH1 . ARG A 1 318 ? 1.20585   -13.25238 23.59486  1.000 63.20704  ? 278 ARG A NH1 1 
ATOM   2096 N NH2 . ARG A 1 318 ? 1.47935   -11.32618 24.79920  1.000 60.51854  ? 278 ARG A NH2 1 
ATOM   2097 N N   . GLN A 1 319 ? 8.25276   -18.00226 24.77911  1.000 43.83163  ? 279 GLN A N   1 
ATOM   2098 C CA  . GLN A 1 319 ? 8.58556   -19.41377 24.88492  1.000 52.26029  ? 279 GLN A CA  1 
ATOM   2099 C C   . GLN A 1 319 ? 9.94627   -19.61746 25.53479  1.000 48.58146  ? 279 GLN A C   1 
ATOM   2100 O O   . GLN A 1 319 ? 10.79415  -18.72414 25.56563  1.000 56.15259  ? 279 GLN A O   1 
ATOM   2101 C CB  . GLN A 1 319 ? 8.56823   -20.08257 23.50622  1.000 51.02771  ? 279 GLN A CB  1 
ATOM   2102 C CG  . GLN A 1 319 ? 7.26516   -19.91677 22.75250  1.000 53.48521  ? 279 GLN A CG  1 
ATOM   2103 C CD  . GLN A 1 319 ? 6.05858   -20.22235 23.61373  1.000 48.91312  ? 279 GLN A CD  1 
ATOM   2104 O OE1 . GLN A 1 319 ? 5.96465   -21.29869 24.20438  1.000 54.88506  ? 279 GLN A OE1 1 
ATOM   2105 N NE2 . GLN A 1 319 ? 5.11987   -19.28457 23.67802  1.000 49.70310  ? 279 GLN A NE2 1 
ATOM   2106 N N   . LYS A 1 320 ? 10.14580  -20.82788 26.04410  1.000 57.90365  ? 280 LYS A N   1 
ATOM   2107 C CA  . LYS A 1 320 ? 11.46595  -21.25611 26.44919  1.000 50.91820  ? 280 LYS A CA  1 
ATOM   2108 C C   . LYS A 1 320 ? 12.29304  -21.47567 25.18539  1.000 50.52405  ? 280 LYS A C   1 
ATOM   2109 O O   . LYS A 1 320 ? 11.73547  -21.66411 24.10104  1.000 59.53462  ? 280 LYS A O   1 
ATOM   2110 C CB  . LYS A 1 320 ? 11.37348  -22.54604 27.26037  1.000 54.55123  ? 280 LYS A CB  1 
ATOM   2111 C CG  . LYS A 1 320 ? 10.53310  -22.43862 28.53698  1.000 54.08035  ? 280 LYS A CG  1 
ATOM   2112 C CD  . LYS A 1 320 ? 11.12932  -21.53206 29.60156  1.000 54.96009  ? 280 LYS A CD  1 
ATOM   2113 C CE  . LYS A 1 320 ? 10.26430  -21.57216 30.86164  1.000 53.26995  ? 280 LYS A CE  1 
ATOM   2114 N NZ  . LYS A 1 320 ? 10.84543  -20.80254 31.99777  1.000 81.09678  ? 280 LYS A NZ  1 
ATOM   2115 N N   . PRO A 1 321 ? 13.61935  -21.41856 25.28336  1.000 53.75795  ? 281 PRO A N   1 
ATOM   2116 C CA  . PRO A 1 321 ? 14.44398  -21.65527 24.09253  1.000 49.25298  ? 281 PRO A CA  1 
ATOM   2117 C C   . PRO A 1 321 ? 14.11354  -22.99335 23.44015  1.000 54.47234  ? 281 PRO A C   1 
ATOM   2118 O O   . PRO A 1 321 ? 13.82744  -23.98568 24.11728  1.000 58.59114  ? 281 PRO A O   1 
ATOM   2119 C CB  . PRO A 1 321 ? 15.87085  -21.62770 24.64399  1.000 48.71603  ? 281 PRO A CB  1 
ATOM   2120 C CG  . PRO A 1 321 ? 15.77596  -20.75117 25.85037  1.000 46.69798  ? 281 PRO A CG  1 
ATOM   2121 C CD  . PRO A 1 321 ? 14.43392  -21.04176 26.45230  1.000 44.90198  ? 281 PRO A CD  1 
ATOM   2122 N N   . GLY A 1 322 ? 14.13751  -23.00439 22.10663  1.000 53.73932  ? 282 GLY A N   1 
ATOM   2123 C CA  . GLY A 1 322 ? 13.82254  -24.19984 21.34570  1.000 50.64036  ? 282 GLY A CA  1 
ATOM   2124 C C   . GLY A 1 322 ? 13.07563  -23.93470 20.05157  1.000 53.68589  ? 282 GLY A C   1 
ATOM   2125 O O   . GLY A 1 322 ? 12.80052  -22.77927 19.71734  1.000 52.21839  ? 282 GLY A O   1 
ATOM   2126 N N   . ALA A 1 323 ? 12.74162  -24.99179 19.31227  1.000 42.19639  ? 283 ALA A N   1 
ATOM   2127 C CA  . ALA A 1 323 ? 11.99997  -24.88541 18.06141  1.000 54.73249  ? 283 ALA A CA  1 
ATOM   2128 C C   . ALA A 1 323 ? 10.60911  -25.48446 18.22734  1.000 52.08904  ? 283 ALA A C   1 
ATOM   2129 O O   . ALA A 1 323 ? 10.44932  -26.54902 18.83434  1.000 53.81163  ? 283 ALA A O   1 
ATOM   2130 C CB  . ALA A 1 323 ? 12.73269  -25.58621 16.91111  1.000 44.00981  ? 283 ALA A CB  1 
ATOM   2131 N N   . TYR A 1 324 ? 9.60348   -24.79168 17.69404  1.000 46.81282  ? 284 TYR A N   1 
ATOM   2132 C CA  . TYR A 1 324 ? 8.21101   -25.18696 17.84939  1.000 55.24968  ? 284 TYR A CA  1 
ATOM   2133 C C   . TYR A 1 324 ? 7.47365   -25.09490 16.52357  1.000 48.96072  ? 284 TYR A C   1 
ATOM   2134 O O   . TYR A 1 324 ? 7.65963   -24.14026 15.76344  1.000 52.64475  ? 284 TYR A O   1 
ATOM   2135 C CB  . TYR A 1 324 ? 7.47500   -24.30224 18.86705  1.000 41.36475  ? 284 TYR A CB  1 
ATOM   2136 C CG  . TYR A 1 324 ? 8.15560   -24.15324 20.20545  1.000 51.94965  ? 284 TYR A CG  1 
ATOM   2137 C CD1 . TYR A 1 324 ? 9.20087   -23.25578 20.38359  1.000 47.12449  ? 284 TYR A CD1 1 
ATOM   2138 C CD2 . TYR A 1 324 ? 7.73909   -24.89788 21.29815  1.000 48.00855  ? 284 TYR A CD2 1 
ATOM   2139 C CE1 . TYR A 1 324 ? 9.81816   -23.11366 21.61196  1.000 46.15819  ? 284 TYR A CE1 1 
ATOM   2140 C CE2 . TYR A 1 324 ? 8.34884   -24.76291 22.52919  1.000 56.09897  ? 284 TYR A CE2 1 
ATOM   2141 C CZ  . TYR A 1 324 ? 9.38738   -23.87074 22.68238  1.000 56.58065  ? 284 TYR A CZ  1 
ATOM   2142 O OH  . TYR A 1 324 ? 9.99543   -23.73689 23.91063  1.000 59.31358  ? 284 TYR A OH  1 
ATOM   2143 N N   . THR A 1 325 ? 6.63566   -26.08978 16.25290  1.000 46.41422  ? 285 THR A N   1 
ATOM   2144 C CA  . THR A 1 325 ? 5.56095   -25.89200 15.29758  1.000 51.49802  ? 285 THR A CA  1 
ATOM   2145 C C   . THR A 1 325 ? 4.38869   -25.21556 16.00673  1.000 47.54294  ? 285 THR A C   1 
ATOM   2146 O O   . THR A 1 325 ? 4.39566   -25.02846 17.22581  1.000 51.74299  ? 285 THR A O   1 
ATOM   2147 C CB  . THR A 1 325 ? 5.13717   -27.21884 14.66976  1.000 44.27822  ? 285 THR A CB  1 
ATOM   2148 O OG1 . THR A 1 325 ? 4.70171   -28.11854 15.69607  1.000 48.77468  ? 285 THR A OG1 1 
ATOM   2149 C CG2 . THR A 1 325 ? 6.29477   -27.84143 13.91223  1.000 47.82082  ? 285 THR A CG2 1 
ATOM   2150 N N   . MET A 1 326 ? 3.36820   -24.83792 15.23579  1.000 47.53086  ? 286 MET A N   1 
ATOM   2151 C CA  . MET A 1 326 ? 2.28299   -24.05361 15.81815  1.000 52.13231  ? 286 MET A CA  1 
ATOM   2152 C C   . MET A 1 326 ? 1.39173   -24.86937 16.75034  1.000 50.56309  ? 286 MET A C   1 
ATOM   2153 O O   . MET A 1 326 ? 0.62810   -24.28003 17.52226  1.000 50.95714  ? 286 MET A O   1 
ATOM   2154 C CB  . MET A 1 326 ? 1.43542   -23.41286 14.71839  1.000 47.06296  ? 286 MET A CB  1 
ATOM   2155 C CG  . MET A 1 326 ? 2.16781   -22.34133 13.92963  1.000 48.51804  ? 286 MET A CG  1 
ATOM   2156 S SD  . MET A 1 326 ? 1.05954   -21.30781 12.95253  1.000 56.60520  ? 286 MET A SD  1 
ATOM   2157 C CE  . MET A 1 326 ? 0.40168   -20.24044 14.22877  1.000 38.76511  ? 286 MET A CE  1 
ATOM   2158 N N   . ILE A 1 327 ? 1.46409   -26.19962 16.70520  1.000 42.60098  ? 287 ILE A N   1 
ATOM   2159 C CA  . ILE A 1 327 ? 0.64209   -27.02815 17.58245  1.000 49.92777  ? 287 ILE A CA  1 
ATOM   2160 C C   . ILE A 1 327 ? 1.36879   -27.29896 18.89462  1.000 43.57513  ? 287 ILE A C   1 
ATOM   2161 O O   . ILE A 1 327 ? 0.89717   -28.08473 19.72374  1.000 52.15852  ? 287 ILE A O   1 
ATOM   2162 C CB  . ILE A 1 327 ? 0.24343   -28.34875 16.89707  1.000 49.93028  ? 287 ILE A CB  1 
ATOM   2163 C CG1 . ILE A 1 327 ? 1.48516   -29.18999 16.59545  1.000 49.00616  ? 287 ILE A CG1 1 
ATOM   2164 C CG2 . ILE A 1 327 ? -0.56194  -28.07236 15.62981  1.000 44.46874  ? 287 ILE A CG2 1 
ATOM   2165 C CD1 . ILE A 1 327 ? 1.17072   -30.55841 16.04279  1.000 44.29980  ? 287 ILE A CD1 1 
ATOM   2166 N N   . GLU A 1 328 ? 2.51434   -26.65056 19.09951  1.000 49.49389  ? 288 GLU A N   1 
ATOM   2167 C CA  . GLU A 1 328 ? 3.28011   -26.80802 20.32893  1.000 50.26438  ? 288 GLU A CA  1 
ATOM   2168 C C   . GLU A 1 328 ? 3.26345   -25.55375 21.19332  1.000 54.96013  ? 288 GLU A C   1 
ATOM   2169 O O   . GLU A 1 328 ? 4.05508   -25.45094 22.13632  1.000 54.50240  ? 288 GLU A O   1 
ATOM   2170 C CB  . GLU A 1 328 ? 4.72351   -27.19622 20.00196  1.000 44.23494  ? 288 GLU A CB  1 
ATOM   2171 C CG  . GLU A 1 328 ? 4.85132   -28.35256 19.02194  1.000 46.54659  ? 288 GLU A CG  1 
ATOM   2172 C CD  . GLU A 1 328 ? 6.29486   -28.68548 18.69206  1.000 55.86940  ? 288 GLU A CD  1 
ATOM   2173 O OE1 . GLU A 1 328 ? 7.10364   -28.83294 19.63011  1.000 58.38008  ? 288 GLU A OE1 1 
ATOM   2174 O OE2 . GLU A 1 328 ? 6.62254   -28.79692 17.49196  1.000 55.32633  ? 288 GLU A OE2 1 
ATOM   2175 N N   . ILE A 1 329 ? 2.38658   -24.60018 20.89767  1.000 52.98099  ? 289 ILE A N   1 
ATOM   2176 C CA  . ILE A 1 329 ? 2.34904   -23.32968 21.61701  1.000 47.05248  ? 289 ILE A CA  1 
ATOM   2177 C C   . ILE A 1 329 ? 0.91851   -23.03951 22.05594  1.000 50.89603  ? 289 ILE A C   1 
ATOM   2178 O O   . ILE A 1 329 ? -0.01576  -23.20797 21.25847  1.000 50.29451  ? 289 ILE A O   1 
ATOM   2179 C CB  . ILE A 1 329 ? 2.91540   -22.19363 20.75007  1.000 58.06903  ? 289 ILE A CB  1 
ATOM   2180 C CG1 . ILE A 1 329 ? 4.38765   -22.45959 20.43326  1.000 46.63036  ? 289 ILE A CG1 1 
ATOM   2181 C CG2 . ILE A 1 329 ? 2.74361   -20.84250 21.43070  1.000 51.24166  ? 289 ILE A CG2 1 
ATOM   2182 C CD1 . ILE A 1 329 ? 5.00658   -21.43217 19.53281  1.000 60.24434  ? 289 ILE A CD1 1 
ATOM   2183 N N   . PRO A 1 330 ? 0.69387   -22.63254 23.30533  1.000 55.05474  ? 290 PRO A N   1 
ATOM   2184 C CA  . PRO A 1 330 ? -0.66090  -22.24014 23.71773  1.000 43.68329  ? 290 PRO A CA  1 
ATOM   2185 C C   . PRO A 1 330 ? -1.20492  -21.13926 22.81838  1.000 49.06998  ? 290 PRO A C   1 
ATOM   2186 O O   . PRO A 1 330 ? -0.51148  -20.16678 22.51042  1.000 51.73195  ? 290 PRO A O   1 
ATOM   2187 C CB  . PRO A 1 330 ? -0.47176  -21.75215 25.15932  1.000 44.04364  ? 290 PRO A CB  1 
ATOM   2188 C CG  . PRO A 1 330 ? 0.81017   -22.34476 25.61614  1.000 50.51085  ? 290 PRO A CG  1 
ATOM   2189 C CD  . PRO A 1 330 ? 1.66900   -22.53480 24.40508  1.000 45.37502  ? 290 PRO A CD  1 
ATOM   2190 N N   . ILE A 1 331 ? -2.45861  -21.31140 22.38899  1.000 47.00441  ? 291 ILE A N   1 
ATOM   2191 C CA  . ILE A 1 331 ? -3.07949  -20.37054 21.45777  1.000 45.87359  ? 291 ILE A CA  1 
ATOM   2192 C C   . ILE A 1 331 ? -3.03589  -18.95162 22.01469  1.000 49.43963  ? 291 ILE A C   1 
ATOM   2193 O O   . ILE A 1 331 ? -2.87035  -17.97921 21.26693  1.000 49.94555  ? 291 ILE A O   1 
ATOM   2194 C CB  . ILE A 1 331 ? -4.51653  -20.81859 21.12773  1.000 51.22968  ? 291 ILE A CB  1 
ATOM   2195 C CG1 . ILE A 1 331 ? -4.49558  -22.17217 20.41419  1.000 47.97043  ? 291 ILE A CG1 1 
ATOM   2196 C CG2 . ILE A 1 331 ? -5.21458  -19.79225 20.25099  1.000 41.82729  ? 291 ILE A CG2 1 
ATOM   2197 C CD1 . ILE A 1 331 ? -5.86919  -22.72899 20.11077  1.000 48.54073  ? 291 ILE A CD1 1 
ATOM   2198 N N   . ILE A 1 332 ? -3.16819  -18.81044 23.33602  1.000 42.27449  ? 292 ILE A N   1 
ATOM   2199 C CA  . ILE A 1 332 ? -3.19633  -17.48415 23.94552  1.000 45.21399  ? 292 ILE A CA  1 
ATOM   2200 C C   . ILE A 1 332 ? -1.87688  -16.74897 23.72567  1.000 54.72463  ? 292 ILE A C   1 
ATOM   2201 O O   . ILE A 1 332 ? -1.84025  -15.51175 23.72876  1.000 54.68463  ? 292 ILE A O   1 
ATOM   2202 C CB  . ILE A 1 332 ? -3.54333  -17.60214 25.44436  1.000 49.09756  ? 292 ILE A CB  1 
ATOM   2203 C CG1 . ILE A 1 332 ? -3.99959  -16.25271 26.00527  1.000 51.20428  ? 292 ILE A CG1 1 
ATOM   2204 C CG2 . ILE A 1 332 ? -2.36129  -18.16149 26.23498  1.000 46.28814  ? 292 ILE A CG2 1 
ATOM   2205 C CD1 . ILE A 1 332 ? -4.51160  -16.32863 27.42586  1.000 46.36396  ? 292 ILE A CD1 1 
ATOM   2206 N N   . ASP A 1 333 ? -0.77609  -17.48427 23.53173  1.000 52.70481  ? 293 ASP A N   1 
ATOM   2207 C CA  . ASP A 1 333 ? 0.51778   -16.83881 23.32719  1.000 56.55570  ? 293 ASP A CA  1 
ATOM   2208 C C   . ASP A 1 333 ? 0.58967   -16.07310 22.01161  1.000 48.09753  ? 293 ASP A C   1 
ATOM   2209 O O   . ASP A 1 333 ? 1.42165   -15.16908 21.88255  1.000 56.68618  ? 293 ASP A O   1 
ATOM   2210 C CB  . ASP A 1 333 ? 1.64742   -17.87123 23.38405  1.000 44.79642  ? 293 ASP A CB  1 
ATOM   2211 C CG  . ASP A 1 333 ? 1.93081   -18.35409 24.79673  1.000 51.45988  ? 293 ASP A CG  1 
ATOM   2212 O OD1 . ASP A 1 333 ? 1.31119   -17.82723 25.74438  1.000 54.71725  ? 293 ASP A OD1 1 
ATOM   2213 O OD2 . ASP A 1 333 ? 2.77383   -19.26240 24.95831  1.000 60.97631  ? 293 ASP A OD2 1 
ATOM   2214 N N   . PHE A 1 334 ? -0.25274  -16.41033 21.03469  1.000 39.06585  ? 294 PHE A N   1 
ATOM   2215 C CA  . PHE A 1 334 ? -0.26850  -15.68248 19.77237  1.000 43.85617  ? 294 PHE A CA  1 
ATOM   2216 C C   . PHE A 1 334 ? -1.08117  -14.39693 19.83823  1.000 55.47631  ? 294 PHE A C   1 
ATOM   2217 O O   . PHE A 1 334 ? -1.02968  -13.60136 18.89351  1.000 49.30508  ? 294 PHE A O   1 
ATOM   2218 C CB  . PHE A 1 334 ? -0.82784  -16.56514 18.65410  1.000 45.50136  ? 294 PHE A CB  1 
ATOM   2219 C CG  . PHE A 1 334 ? -0.00353  -17.78583 18.37067  1.000 50.37496  ? 294 PHE A CG  1 
ATOM   2220 C CD1 . PHE A 1 334 ? 1.08032   -17.72277 17.50949  1.000 48.29579  ? 294 PHE A CD1 1 
ATOM   2221 C CD2 . PHE A 1 334 ? -0.32219  -19.00412 18.95360  1.000 49.31805  ? 294 PHE A CD2 1 
ATOM   2222 C CE1 . PHE A 1 334 ? 1.83971   -18.84961 17.24234  1.000 47.85899  ? 294 PHE A CE1 1 
ATOM   2223 C CE2 . PHE A 1 334 ? 0.43175   -20.13393 18.68817  1.000 50.13166  ? 294 PHE A CE2 1 
ATOM   2224 C CZ  . PHE A 1 334 ? 1.51300   -20.05566 17.83285  1.000 43.66956  ? 294 PHE A CZ  1 
ATOM   2225 N N   . LEU A 1 335 ? -1.82089  -14.17455 20.91908  1.000 49.36675  ? 295 LEU A N   1 
ATOM   2226 C CA  . LEU A 1 335 ? -2.75504  -13.06329 21.01907  1.000 50.07396  ? 295 LEU A CA  1 
ATOM   2227 C C   . LEU A 1 335 ? -2.16146  -11.94421 21.86243  1.000 54.58274  ? 295 LEU A C   1 
ATOM   2228 O O   . LEU A 1 335 ? -1.44498  -12.19674 22.83535  1.000 56.24723  ? 295 LEU A O   1 
ATOM   2229 C CB  . LEU A 1 335 ? -4.08037  -13.52664 21.62751  1.000 47.16702  ? 295 LEU A CB  1 
ATOM   2230 C CG  . LEU A 1 335 ? -4.89232  -14.51868 20.79356  1.000 51.65364  ? 295 LEU A CG  1 
ATOM   2231 C CD1 . LEU A 1 335 ? -5.89403  -15.25834 21.66551  1.000 49.47141  ? 295 LEU A CD1 1 
ATOM   2232 C CD2 . LEU A 1 335 ? -5.60229  -13.79616 19.65663  1.000 45.02069  ? 295 LEU A CD2 1 
ATOM   2233 N N   . TYR A 1 336 ? -2.45850  -10.70689 21.47822  1.000 49.32837  ? 296 TYR A N   1 
ATOM   2234 C CA  . TYR A 1 336 ? -2.06890  -9.54300  22.25761  1.000 50.09884  ? 296 TYR A CA  1 
ATOM   2235 C C   . TYR A 1 336 ? -3.16479  -9.20993  23.26239  1.000 47.59828  ? 296 TYR A C   1 
ATOM   2236 O O   . TYR A 1 336 ? -4.35517  -9.27608  22.94488  1.000 56.33934  ? 296 TYR A O   1 
ATOM   2237 C CB  . TYR A 1 336 ? -1.80362  -8.34472  21.34260  1.000 50.80347  ? 296 TYR A CB  1 
ATOM   2238 C CG  . TYR A 1 336 ? -1.50416  -7.05881  22.08096  1.000 62.66263  ? 296 TYR A CG  1 
ATOM   2239 C CD1 . TYR A 1 336 ? -0.27163  -6.86532  22.69138  1.000 61.81007  ? 296 TYR A CD1 1 
ATOM   2240 C CD2 . TYR A 1 336 ? -2.44086  -6.03630  22.15950  1.000 60.75206  ? 296 TYR A CD2 1 
ATOM   2241 C CE1 . TYR A 1 336 ? 0.01983   -5.69666  23.36487  1.000 57.39469  ? 296 TYR A CE1 1 
ATOM   2242 C CE2 . TYR A 1 336 ? -2.15706  -4.85930  22.83582  1.000 64.40220  ? 296 TYR A CE2 1 
ATOM   2243 C CZ  . TYR A 1 336 ? -0.92480  -4.69694  23.43564  1.000 70.49623  ? 296 TYR A CZ  1 
ATOM   2244 O OH  . TYR A 1 336 ? -0.63020  -3.53268  24.10849  1.000 71.90010  ? 296 TYR A OH  1 
ATOM   2245 N N   . GLY A 1 337 ? -2.76025  -8.85851  24.47581  1.000 55.59358  ? 297 GLY A N   1 
ATOM   2246 C CA  . GLY A 1 337 ? -3.68457  -8.39104  25.48863  1.000 52.51152  ? 297 GLY A CA  1 
ATOM   2247 C C   . GLY A 1 337 ? -3.48929  -9.09699  26.81634  1.000 58.25511  ? 297 GLY A C   1 
ATOM   2248 O O   . GLY A 1 337 ? -2.71930  -10.04559 26.95189  1.000 56.15695  ? 297 GLY A O   1 
ATOM   2249 N N   . ASP A 1 338 ? -4.22417  -8.59789  27.80749  1.000 65.40544  ? 298 ASP A N   1 
ATOM   2250 C CA  . ASP A 1 338 ? -4.22206  -9.19093  29.13754  1.000 68.58623  ? 298 ASP A CA  1 
ATOM   2251 C C   . ASP A 1 338 ? -4.81852  -10.59309 29.10861  1.000 66.04647  ? 298 ASP A C   1 
ATOM   2252 O O   . ASP A 1 338 ? -5.83327  -10.83954 28.45098  1.000 63.50159  ? 298 ASP A O   1 
ATOM   2253 C CB  . ASP A 1 338 ? -5.00031  -8.30438  30.10826  1.000 58.95858  ? 298 ASP A CB  1 
ATOM   2254 C CG  . ASP A 1 338 ? -5.15626  -8.93347  31.47722  1.000 64.58676  ? 298 ASP A CG  1 
ATOM   2255 O OD1 . ASP A 1 338 ? -4.13059  -9.33207  32.06976  1.000 91.96936  ? 298 ASP A OD1 1 
ATOM   2256 O OD2 . ASP A 1 338 ? -6.30305  -9.02292  31.96361  1.000 68.20633  ? 298 ASP A OD2 1 
ATOM   2257 N N   . ARG A 1 339 ? -4.17001  -11.51691 29.82458  1.000 57.26700  ? 299 ARG A N   1 
ATOM   2258 C CA  . ARG A 1 339 ? -4.59086  -12.91599 29.80625  1.000 61.58368  ? 299 ARG A CA  1 
ATOM   2259 C C   . ARG A 1 339 ? -6.04104  -13.07440 30.24839  1.000 65.56216  ? 299 ARG A C   1 
ATOM   2260 O O   . ARG A 1 339 ? -6.83173  -13.75292 29.58293  1.000 65.23376  ? 299 ARG A O   1 
ATOM   2261 C CB  . ARG A 1 339 ? -3.67458  -13.74977 30.70061  1.000 60.18231  ? 299 ARG A CB  1 
ATOM   2262 C CG  . ARG A 1 339 ? -2.20888  -13.39019 30.59554  1.000 84.67835  ? 299 ARG A CG  1 
ATOM   2263 C CD  . ARG A 1 339 ? -1.34674  -14.46819 31.22208  1.000 89.81048  ? 299 ARG A CD  1 
ATOM   2264 N NE  . ARG A 1 339 ? -1.44344  -15.71694 30.47698  1.000 87.95803  ? 299 ARG A NE  1 
ATOM   2265 C CZ  . ARG A 1 339 ? -1.04528  -16.89665 30.93153  1.000 80.68750  ? 299 ARG A CZ  1 
ATOM   2266 N NH1 . ARG A 1 339 ? -0.51733  -17.03125 32.13752  1.000 83.37941  ? 299 ARG A NH1 1 
ATOM   2267 N NH2 . ARG A 1 339 ? -1.17887  -17.96816 30.15557  1.000 71.30763  ? 299 ARG A NH2 1 
ATOM   2268 N N   . ASP A 1 340 ? -6.40923  -12.45713 31.37417  1.000 58.15169  ? 300 ASP A N   1 
ATOM   2269 C CA  . ASP A 1 340 ? -7.77301  -12.59984 31.87672  1.000 61.39591  ? 300 ASP A CA  1 
ATOM   2270 C C   . ASP A 1 340 ? -8.78735  -11.96182 30.93608  1.000 63.72943  ? 300 ASP A C   1 
ATOM   2271 O O   . ASP A 1 340 ? -9.89088  -12.49063 30.75642  1.000 60.47019  ? 300 ASP A O   1 
ATOM   2272 C CB  . ASP A 1 340 ? -7.89054  -12.00096 33.27859  1.000 54.01922  ? 300 ASP A CB  1 
ATOM   2273 C CG  . ASP A 1 340 ? -7.58939  -13.01141 34.37147  1.000 61.81400  ? 300 ASP A CG  1 
ATOM   2274 O OD1 . ASP A 1 340 ? -7.32495  -14.18601 34.03753  1.000 63.64215  ? 300 ASP A OD1 1 
ATOM   2275 O OD2 . ASP A 1 340 ? -7.62208  -12.63467 35.56198  1.000 57.37857  ? 300 ASP A OD2 1 
ATOM   2276 N N   . GLU A 1 341 ? -8.44007  -10.82317 30.33200  1.000 61.74726  ? 301 GLU A N   1 
ATOM   2277 C CA  . GLU A 1 341 ? -9.37148  -10.17639 29.41401  1.000 65.73702  ? 301 GLU A CA  1 
ATOM   2278 C C   . GLU A 1 341 ? -9.55675  -10.98927 28.13908  1.000 55.33619  ? 301 GLU A C   1 
ATOM   2279 O O   . GLU A 1 341 ? -10.65509 -11.00659 27.57176  1.000 61.89598  ? 301 GLU A O   1 
ATOM   2280 C CB  . GLU A 1 341 ? -8.89238  -8.76345  29.07689  1.000 71.39662  ? 301 GLU A CB  1 
ATOM   2281 C CG  . GLU A 1 341 ? -9.82681  -7.66055  29.55522  1.000 93.35495  ? 301 GLU A CG  1 
ATOM   2282 C CD  . GLU A 1 341 ? -9.51917  -7.20005  30.96720  1.000 109.67192 ? 301 GLU A CD  1 
ATOM   2283 O OE1 . GLU A 1 341 ? -8.43321  -6.62152  31.17990  1.000 105.34639 ? 301 GLU A OE1 1 
ATOM   2284 O OE2 . GLU A 1 341 ? -10.36085 -7.41937  31.86288  1.000 113.68046 ? 301 GLU A OE2 1 
ATOM   2285 N N   . LEU A 1 342 ? -8.50119  -11.66118 27.67219  1.000 56.38612  ? 302 LEU A N   1 
ATOM   2286 C CA  . LEU A 1 342 ? -8.63905  -12.54379 26.51816  1.000 51.48126  ? 302 LEU A CA  1 
ATOM   2287 C C   . LEU A 1 342 ? -9.52915  -13.73653 26.84196  1.000 57.21021  ? 302 LEU A C   1 
ATOM   2288 O O   . LEU A 1 342 ? -10.36292 -14.13727 26.02140  1.000 53.84408  ? 302 LEU A O   1 
ATOM   2289 C CB  . LEU A 1 342 ? -7.26377  -13.00762 26.03943  1.000 50.82735  ? 302 LEU A CB  1 
ATOM   2290 C CG  . LEU A 1 342 ? -6.39565  -11.95205 25.35580  1.000 58.25716  ? 302 LEU A CG  1 
ATOM   2291 C CD1 . LEU A 1 342 ? -4.97953  -12.46961 25.14968  1.000 51.80716  ? 302 LEU A CD1 1 
ATOM   2292 C CD2 . LEU A 1 342 ? -7.02393  -11.55090 24.03199  1.000 45.91400  ? 302 LEU A CD2 1 
ATOM   2293 N N   . ILE A 1 343 ? -9.35537  -14.32538 28.02699  1.000 49.48190  ? 303 ILE A N   1 
ATOM   2294 C CA  . ILE A 1 343 ? -10.17921 -15.46330 28.42178  1.000 51.26111  ? 303 ILE A CA  1 
ATOM   2295 C C   . ILE A 1 343 ? -11.63940 -15.04133 28.52798  1.000 58.25011  ? 303 ILE A C   1 
ATOM   2296 O O   . ILE A 1 343 ? -12.54766 -15.76375 28.09785  1.000 56.71551  ? 303 ILE A O   1 
ATOM   2297 C CB  . ILE A 1 343 ? -9.65963  -16.05068 29.74681  1.000 50.38107  ? 303 ILE A CB  1 
ATOM   2298 C CG1 . ILE A 1 343 ? -8.25786  -16.64233 29.56574  1.000 45.26248  ? 303 ILE A CG1 1 
ATOM   2299 C CG2 . ILE A 1 343 ? -10.61866 -17.10460 30.28321  1.000 49.86806  ? 303 ILE A CG2 1 
ATOM   2300 C CD1 . ILE A 1 343 ? -7.60497  -17.04228 30.87264  1.000 46.23615  ? 303 ILE A CD1 1 
ATOM   2301 N N   . ARG A 1 344 ? -11.88464 -13.85992 29.10035  1.000 56.71018  ? 304 ARG A N   1 
ATOM   2302 C CA  . ARG A 1 344 ? -13.24261 -13.33499 29.20057  1.000 51.52548  ? 304 ARG A CA  1 
ATOM   2303 C C   . ARG A 1 344 ? -13.85060 -13.08469 27.82369  1.000 46.80841  ? 304 ARG A C   1 
ATOM   2304 O O   . ARG A 1 344 ? -15.05812 -13.27659 27.63495  1.000 53.66784  ? 304 ARG A O   1 
ATOM   2305 C CB  . ARG A 1 344 ? -13.24160 -12.06099 30.05232  1.000 51.77349  ? 304 ARG A CB  1 
ATOM   2306 C CG  . ARG A 1 344 ? -14.59600 -11.38871 30.22191  1.000 53.07689  ? 304 ARG A CG  1 
ATOM   2307 C CD  . ARG A 1 344 ? -14.50452 -10.19958 31.17200  1.000 63.32392  ? 304 ARG A CD  1 
ATOM   2308 N NE  . ARG A 1 344 ? -14.05643 -10.60341 32.50110  1.000 70.61371  ? 304 ARG A NE  1 
ATOM   2309 C CZ  . ARG A 1 344 ? -12.87010 -10.31401 33.01897  1.000 79.83714  ? 304 ARG A CZ  1 
ATOM   2310 N NH1 . ARG A 1 344 ? -11.97406 -9.61112  32.34561  1.000 69.40945  ? 304 ARG A NH1 1 
ATOM   2311 N NH2 . ARG A 1 344 ? -12.57567 -10.74080 34.24393  1.000 74.52533  ? 304 ARG A NH2 1 
ATOM   2312 N N   . ARG A 1 345 ? -13.03766 -12.65740 26.85161  1.000 53.11298  ? 305 ARG A N   1 
ATOM   2313 C CA  . ARG A 1 345 ? -13.56845 -12.30920 25.53721  1.000 50.19665  ? 305 ARG A CA  1 
ATOM   2314 C C   . ARG A 1 345 ? -13.77559 -13.52616 24.64427  1.000 55.42971  ? 305 ARG A C   1 
ATOM   2315 O O   . ARG A 1 345 ? -14.66578 -13.51329 23.78710  1.000 58.99615  ? 305 ARG A O   1 
ATOM   2316 C CB  . ARG A 1 345 ? -12.61834 -11.35078 24.81582  1.000 57.34367  ? 305 ARG A CB  1 
ATOM   2317 C CG  . ARG A 1 345 ? -13.19470 -10.74241 23.54060  1.000 61.14066  ? 305 ARG A CG  1 
ATOM   2318 C CD  . ARG A 1 345 ? -12.09757 -10.32574 22.56404  1.000 59.80481  ? 305 ARG A CD  1 
ATOM   2319 N NE  . ARG A 1 345 ? -11.01669 -9.56988  23.18347  1.000 53.97309  ? 305 ARG A NE  1 
ATOM   2320 C CZ  . ARG A 1 345 ? -9.81665  -9.41142  22.64125  1.000 70.24706  ? 305 ARG A CZ  1 
ATOM   2321 N NH1 . ARG A 1 345 ? -9.51131  -9.94817  21.47079  1.000 55.61007  ? 305 ARG A NH1 1 
ATOM   2322 N NH2 . ARG A 1 345 ? -8.90153  -8.69319  23.28672  1.000 74.38825  ? 305 ARG A NH2 1 
ATOM   2323 N N   . LEU A 1 346 ? -12.98790 -14.58156 24.82999  1.000 56.09953  ? 306 LEU A N   1 
ATOM   2324 C CA  . LEU A 1 346 ? -12.90356 -15.65194 23.84583  1.000 53.20648  ? 306 LEU A CA  1 
ATOM   2325 C C   . LEU A 1 346 ? -13.32289 -17.01908 24.35946  1.000 53.79374  ? 306 LEU A C   1 
ATOM   2326 O O   . LEU A 1 346 ? -13.81685 -17.82782 23.56999  1.000 52.86403  ? 306 LEU A O   1 
ATOM   2327 C CB  . LEU A 1 346 ? -11.47263 -15.74667 23.29199  1.000 55.58907  ? 306 LEU A CB  1 
ATOM   2328 C CG  . LEU A 1 346 ? -11.03686 -14.55800 22.43469  1.000 52.53518  ? 306 LEU A CG  1 
ATOM   2329 C CD1 . LEU A 1 346 ? -9.55087  -14.62620 22.14518  1.000 46.03599  ? 306 LEU A CD1 1 
ATOM   2330 C CD2 . LEU A 1 346 ? -11.82791 -14.53646 21.14003  1.000 47.58063  ? 306 LEU A CD2 1 
ATOM   2331 N N   . VAL A 1 347 ? -13.15003 -17.30217 25.64522  1.000 48.49362  ? 307 VAL A N   1 
ATOM   2332 C CA  . VAL A 1 347 ? -13.45118 -18.63006 26.16070  1.000 52.40637  ? 307 VAL A CA  1 
ATOM   2333 C C   . VAL A 1 347 ? -14.93423 -18.75113 26.47776  1.000 63.16979  ? 307 VAL A C   1 
ATOM   2334 O O   . VAL A 1 347 ? -15.62698 -19.59511 25.90824  1.000 67.69045  ? 307 VAL A O   1 
ATOM   2335 C CB  . VAL A 1 347 ? -12.60556 -18.95087 27.40474  1.000 53.38715  ? 307 VAL A CB  1 
ATOM   2336 C CG1 . VAL A 1 347 ? -13.00196 -20.29897 27.97754  1.000 41.28842  ? 307 VAL A CG1 1 
ATOM   2337 C CG2 . VAL A 1 347 ? -11.12865 -18.92505 27.06301  1.000 52.07598  ? 307 VAL A CG2 1 
ATOM   2338 O OXT . VAL A 1 347 ? -15.47337 -18.00743 27.29812  1.000 72.13470  ? 307 VAL A OXT 1 
ATOM   2339 N N   . SER B 1 42  ? 34.17036  -16.90800 56.65811  1.000 105.14143 ? 2   SER B N   1 
ATOM   2340 C CA  . SER B 1 42  ? 32.94517  -16.88388 55.86776  1.000 108.13651 ? 2   SER B CA  1 
ATOM   2341 C C   . SER B 1 42  ? 31.84220  -17.68738 56.54814  1.000 106.20400 ? 2   SER B C   1 
ATOM   2342 O O   . SER B 1 42  ? 31.80207  -18.91368 56.44617  1.000 101.13105 ? 2   SER B O   1 
ATOM   2343 C CB  . SER B 1 42  ? 33.20311  -17.42864 54.46059  1.000 105.47239 ? 2   SER B CB  1 
ATOM   2344 O OG  . SER B 1 42  ? 32.02585  -17.38785 53.67248  1.000 96.91809  ? 2   SER B OG  1 
ATOM   2345 N N   . GLU B 1 43  ? 30.94708  -16.98870 57.24568  1.000 99.77916  ? 3   GLU B N   1 
ATOM   2346 C CA  . GLU B 1 43  ? 29.82762  -17.61847 57.93003  1.000 99.07398  ? 3   GLU B CA  1 
ATOM   2347 C C   . GLU B 1 43  ? 28.57646  -17.69029 57.06345  1.000 95.77397  ? 3   GLU B C   1 
ATOM   2348 O O   . GLU B 1 43  ? 27.47339  -17.86884 57.59301  1.000 85.16474  ? 3   GLU B O   1 
ATOM   2349 C CB  . GLU B 1 43  ? 29.52421  -16.88047 59.23579  1.000 99.22217  ? 3   GLU B CB  1 
ATOM   2350 C CG  . GLU B 1 43  ? 30.70085  -16.81744 60.19775  1.000 108.43929 ? 3   GLU B CG  1 
ATOM   2351 C CD  . GLU B 1 43  ? 31.17425  -18.19028 60.64375  1.000 125.47117 ? 3   GLU B CD  1 
ATOM   2352 O OE1 . GLU B 1 43  ? 30.36490  -19.14136 60.62475  1.000 125.90487 ? 3   GLU B OE1 1 
ATOM   2353 O OE2 . GLU B 1 43  ? 32.35975  -18.31834 61.01483  1.000 119.94695 ? 3   GLU B OE2 1 
ATOM   2354 N N   . ILE B 1 44  ? 28.72332  -17.54775 55.74755  1.000 87.83029  ? 4   ILE B N   1 
ATOM   2355 C CA  . ILE B 1 44  ? 27.58965  -17.68392 54.84496  1.000 77.73601  ? 4   ILE B CA  1 
ATOM   2356 C C   . ILE B 1 44  ? 27.15341  -19.14095 54.80936  1.000 72.66061  ? 4   ILE B C   1 
ATOM   2357 O O   . ILE B 1 44  ? 27.96920  -20.04267 54.57386  1.000 80.59576  ? 4   ILE B O   1 
ATOM   2358 C CB  . ILE B 1 44  ? 27.95945  -17.17875 53.44314  1.000 70.95523  ? 4   ILE B CB  1 
ATOM   2359 C CG1 . ILE B 1 44  ? 28.34492  -15.69727 53.49063  1.000 69.55969  ? 4   ILE B CG1 1 
ATOM   2360 C CG2 . ILE B 1 44  ? 26.81645  -17.41822 52.47481  1.000 59.52173  ? 4   ILE B CG2 1 
ATOM   2361 C CD1 . ILE B 1 44  ? 28.93311  -15.17699 52.19686  1.000 72.98617  ? 4   ILE B CD1 1 
ATOM   2362 N N   . ARG B 1 45  ? 25.86678  -19.38024 55.05975  1.000 72.48435  ? 5   ARG B N   1 
ATOM   2363 C CA  . ARG B 1 45  ? 25.34029  -20.73640 54.98626  1.000 67.65262  ? 5   ARG B CA  1 
ATOM   2364 C C   . ARG B 1 45  ? 25.59059  -21.34054 53.61169  1.000 71.88941  ? 5   ARG B C   1 
ATOM   2365 O O   . ARG B 1 45  ? 25.38883  -20.69366 52.57997  1.000 61.40215  ? 5   ARG B O   1 
ATOM   2366 C CB  . ARG B 1 45  ? 23.84740  -20.75621 55.31775  1.000 62.88427  ? 5   ARG B CB  1 
ATOM   2367 C CG  . ARG B 1 45  ? 23.24606  -22.15300 55.31214  1.000 68.19024  ? 5   ARG B CG  1 
ATOM   2368 C CD  . ARG B 1 45  ? 22.04001  -22.26059 56.22260  1.000 78.16475  ? 5   ARG B CD  1 
ATOM   2369 N NE  . ARG B 1 45  ? 22.43763  -22.15868 57.62187  1.000 96.52508  ? 5   ARG B NE  1 
ATOM   2370 C CZ  . ARG B 1 45  ? 21.60746  -21.94088 58.63251  1.000 93.79298  ? 5   ARG B CZ  1 
ATOM   2371 N NH1 . ARG B 1 45  ? 20.31093  -21.76295 58.43770  1.000 89.56665  ? 5   ARG B NH1 1 
ATOM   2372 N NH2 . ARG B 1 45  ? 22.09021  -21.90667 59.87150  1.000 92.14525  ? 5   ARG B NH2 1 
ATOM   2373 N N   . THR B 1 46  ? 26.03359  -22.59434 53.60822  1.000 74.99936  ? 6   THR B N   1 
ATOM   2374 C CA  . THR B 1 46  ? 26.23016  -23.32127 52.36889  1.000 62.72187  ? 6   THR B CA  1 
ATOM   2375 C C   . THR B 1 46  ? 24.91792  -23.94029 51.89953  1.000 63.75961  ? 6   THR B C   1 
ATOM   2376 O O   . THR B 1 46  ? 23.97972  -24.14913 52.67444  1.000 60.22934  ? 6   THR B O   1 
ATOM   2377 C CB  . THR B 1 46  ? 27.28974  -24.40784 52.54560  1.000 64.23306  ? 6   THR B CB  1 
ATOM   2378 O OG1 . THR B 1 46  ? 27.13073  -25.02962 53.82690  1.000 90.04221  ? 6   THR B OG1 1 
ATOM   2379 C CG2 . THR B 1 46  ? 28.68228  -23.81558 52.44857  1.000 75.29413  ? 6   THR B CG2 1 
ATOM   2380 N N   . GLU B 1 47  ? 24.86115  -24.22750 50.60317  1.000 62.94847  ? 7   GLU B N   1 
ATOM   2381 C CA  . GLU B 1 47  ? 23.63891  -24.73023 49.99997  1.000 71.14992  ? 7   GLU B CA  1 
ATOM   2382 C C   . GLU B 1 47  ? 23.29116  -26.10759 50.57625  1.000 65.65601  ? 7   GLU B C   1 
ATOM   2383 O O   . GLU B 1 47  ? 24.10950  -26.77306 51.21976  1.000 66.46830  ? 7   GLU B O   1 
ATOM   2384 C CB  . GLU B 1 47  ? 23.78587  -24.74963 48.47717  1.000 71.47293  ? 7   GLU B CB  1 
ATOM   2385 C CG  . GLU B 1 47  ? 22.47417  -24.68546 47.71312  1.000 78.91329  ? 7   GLU B CG  1 
ATOM   2386 C CD  . GLU B 1 47  ? 22.68580  -24.71357 46.21349  1.000 84.77067  ? 7   GLU B CD  1 
ATOM   2387 O OE1 . GLU B 1 47  ? 23.85658  -24.75822 45.77706  1.000 76.35561  ? 7   GLU B OE1 1 
ATOM   2388 O OE2 . GLU B 1 47  ? 21.68490  -24.66098 45.47045  1.000 70.66267  ? 7   GLU B OE2 1 
ATOM   2389 N N   . ARG B 1 48  ? 22.05423  -26.53769 50.33062  1.000 63.52255  ? 8   ARG B N   1 
ATOM   2390 C CA  . ARG B 1 48  ? 21.55057  -27.77363 50.92457  1.000 64.38163  ? 8   ARG B CA  1 
ATOM   2391 C C   . ARG B 1 48  ? 21.91180  -28.97053 50.04878  1.000 55.54580  ? 8   ARG B C   1 
ATOM   2392 O O   . ARG B 1 48  ? 21.89189  -28.86650 48.81777  1.000 60.43798  ? 8   ARG B O   1 
ATOM   2393 C CB  . ARG B 1 48  ? 20.03434  -27.73454 51.10989  1.000 54.05019  ? 8   ARG B CB  1 
ATOM   2394 C CG  . ARG B 1 48  ? 19.24365  -27.69335 49.82065  1.000 68.34767  ? 8   ARG B CG  1 
ATOM   2395 C CD  . ARG B 1 48  ? 17.75136  -27.77893 50.07981  1.000 70.40770  ? 8   ARG B CD  1 
ATOM   2396 N NE  . ARG B 1 48  ? 17.00009  -27.78933 48.83100  1.000 80.11737  ? 8   ARG B NE  1 
ATOM   2397 C CZ  . ARG B 1 48  ? 16.80936  -28.87375 48.09067  1.000 75.23999  ? 8   ARG B CZ  1 
ATOM   2398 N NH1 . ARG B 1 48  ? 17.31085  -30.04707 48.44177  1.000 69.00488  ? 8   ARG B NH1 1 
ATOM   2399 N NH2 . ARG B 1 48  ? 16.10934  -28.77696 46.96393  1.000 63.82973  ? 8   ARG B NH2 1 
ATOM   2400 N N   . PRO B 1 49  ? 22.29458  -30.09389 50.65572  1.000 60.56462  ? 9   PRO B N   1 
ATOM   2401 C CA  . PRO B 1 49  ? 22.72084  -31.24902 49.85863  1.000 61.13842  ? 9   PRO B CA  1 
ATOM   2402 C C   . PRO B 1 49  ? 21.60034  -31.76324 48.96628  1.000 53.02532  ? 9   PRO B C   1 
ATOM   2403 O O   . PRO B 1 49  ? 20.41258  -31.58849 49.24899  1.000 57.54560  ? 9   PRO B O   1 
ATOM   2404 C CB  . PRO B 1 49  ? 23.10862  -32.28542 50.91888  1.000 57.49012  ? 9   PRO B CB  1 
ATOM   2405 C CG  . PRO B 1 49  ? 22.27524  -31.91889 52.10858  1.000 63.56183  ? 9   PRO B CG  1 
ATOM   2406 C CD  . PRO B 1 49  ? 22.21566  -30.41349 52.09228  1.000 55.87407  ? 9   PRO B CD  1 
ATOM   2407 N N   . ILE B 1 50  ? 22.00078  -32.39964 47.86676  1.000 46.61820  ? 10  ILE B N   1 
ATOM   2408 C CA  . ILE B 1 50  ? 21.04265  -32.98793 46.94077  1.000 49.65779  ? 10  ILE B CA  1 
ATOM   2409 C C   . ILE B 1 50  ? 20.43578  -34.23573 47.56661  1.000 54.88409  ? 10  ILE B C   1 
ATOM   2410 O O   . ILE B 1 50  ? 21.15398  -35.12636 48.04187  1.000 54.31385  ? 10  ILE B O   1 
ATOM   2411 C CB  . ILE B 1 50  ? 21.72447  -33.31991 45.60530  1.000 53.18271  ? 10  ILE B CB  1 
ATOM   2412 C CG1 . ILE B 1 50  ? 22.54787  -32.12936 45.11186  1.000 47.74468  ? 10  ILE B CG1 1 
ATOM   2413 C CG2 . ILE B 1 50  ? 20.69160  -33.70778 44.55952  1.000 48.51215  ? 10  ILE B CG2 1 
ATOM   2414 C CD1 . ILE B 1 50  ? 23.47516  -32.47083 43.96295  1.000 38.73061  ? 10  ILE B CD1 1 
ATOM   2415 N N   . ARG B 1 51  ? 19.10795  -34.30979 47.57001  1.000 48.52892  ? 11  ARG B N   1 
ATOM   2416 C CA  . ARG B 1 51  ? 18.40819  -35.46752 48.11188  1.000 61.45236  ? 11  ARG B CA  1 
ATOM   2417 C C   . ARG B 1 51  ? 18.17847  -36.46255 46.98079  1.000 56.12802  ? 11  ARG B C   1 
ATOM   2418 O O   . ARG B 1 51  ? 17.44321  -36.17360 46.03014  1.000 54.96044  ? 11  ARG B O   1 
ATOM   2419 C CB  . ARG B 1 51  ? 17.08641  -35.05991 48.76343  1.000 52.49669  ? 11  ARG B CB  1 
ATOM   2420 C CG  . ARG B 1 51  ? 17.23977  -34.06337 49.90538  1.000 51.73709  ? 11  ARG B CG  1 
ATOM   2421 C CD  . ARG B 1 51  ? 16.06271  -34.12332 50.87343  1.000 63.55657  ? 11  ARG B CD  1 
ATOM   2422 N NE  . ARG B 1 51  ? 16.19605  -35.21487 51.83190  1.000 63.41714  ? 11  ARG B NE  1 
ATOM   2423 C CZ  . ARG B 1 51  ? 15.34772  -36.22871 51.94169  1.000 62.26455  ? 11  ARG B CZ  1 
ATOM   2424 N NH1 . ARG B 1 51  ? 14.27944  -36.32469 51.16685  1.000 57.56262  ? 11  ARG B NH1 1 
ATOM   2425 N NH2 . ARG B 1 51  ? 15.57224  -37.16550 52.85850  1.000 70.20411  ? 11  ARG B NH2 1 
ATOM   2426 N N   . VAL B 1 52  ? 18.81011  -37.62861 47.08536  1.000 48.60721  ? 12  VAL B N   1 
ATOM   2427 C CA  . VAL B 1 52  ? 18.83161  -38.62627 46.02223  1.000 50.93420  ? 12  VAL B CA  1 
ATOM   2428 C C   . VAL B 1 52  ? 18.06758  -39.85503 46.49024  1.000 52.98980  ? 12  VAL B C   1 
ATOM   2429 O O   . VAL B 1 52  ? 18.27555  -40.33488 47.61154  1.000 54.41651  ? 12  VAL B O   1 
ATOM   2430 C CB  . VAL B 1 52  ? 20.27299  -38.99467 45.62789  1.000 50.75044  ? 12  VAL B CB  1 
ATOM   2431 C CG1 . VAL B 1 52  ? 20.27881  -40.12608 44.60390  1.000 47.35237  ? 12  VAL B CG1 1 
ATOM   2432 C CG2 . VAL B 1 52  ? 21.00086  -37.77615 45.08754  1.000 44.54542  ? 12  VAL B CG2 1 
ATOM   2433 N N   . ALA B 1 53  ? 17.18340  -40.35772 45.63507  1.000 51.48997  ? 13  ALA B N   1 
ATOM   2434 C CA  . ALA B 1 53  ? 16.49275  -41.61723 45.85841  1.000 55.09640  ? 13  ALA B CA  1 
ATOM   2435 C C   . ALA B 1 53  ? 17.03665  -42.66436 44.89591  1.000 52.46546  ? 13  ALA B C   1 
ATOM   2436 O O   . ALA B 1 53  ? 17.31636  -42.36676 43.72973  1.000 50.99654  ? 13  ALA B O   1 
ATOM   2437 C CB  . ALA B 1 53  ? 14.98059  -41.45999 45.67457  1.000 47.54653  ? 13  ALA B CB  1 
ATOM   2438 N N   . ILE B 1 54  ? 17.19637  -43.88562 45.39017  1.000 51.68339  ? 14  ILE B N   1 
ATOM   2439 C CA  . ILE B 1 54  ? 17.68712  -44.99930 44.58990  1.000 61.97461  ? 14  ILE B CA  1 
ATOM   2440 C C   . ILE B 1 54  ? 16.49187  -45.85662 44.20331  1.000 45.70979  ? 14  ILE B C   1 
ATOM   2441 O O   . ILE B 1 54  ? 15.78333  -46.37654 45.07309  1.000 52.66548  ? 14  ILE B O   1 
ATOM   2442 C CB  . ILE B 1 54  ? 18.74058  -45.81662 45.35320  1.000 57.74391  ? 14  ILE B CB  1 
ATOM   2443 C CG1 . ILE B 1 54  ? 19.96717  -44.95232 45.64932  1.000 49.50376  ? 14  ILE B CG1 1 
ATOM   2444 C CG2 . ILE B 1 54  ? 19.14039  -47.04826 44.55791  1.000 49.53405  ? 14  ILE B CG2 1 
ATOM   2445 C CD1 . ILE B 1 54  ? 20.95691  -45.60901 46.56919  1.000 53.89502  ? 14  ILE B CD1 1 
ATOM   2446 N N   . ILE B 1 55  ? 16.26779  -46.00129 42.90174  1.000 47.36671  ? 15  ILE B N   1 
ATOM   2447 C CA  . ILE B 1 55  ? 15.13378  -46.74455 42.36472  1.000 51.72947  ? 15  ILE B CA  1 
ATOM   2448 C C   . ILE B 1 55  ? 15.64096  -48.11980 41.95200  1.000 59.74128  ? 15  ILE B C   1 
ATOM   2449 O O   . ILE B 1 55  ? 16.37712  -48.25279 40.96867  1.000 50.47215  ? 15  ILE B O   1 
ATOM   2450 C CB  . ILE B 1 55  ? 14.48561  -46.01212 41.18163  1.000 55.59199  ? 15  ILE B CB  1 
ATOM   2451 C CG1 . ILE B 1 55  ? 14.34045  -44.51970 41.48504  1.000 45.46036  ? 15  ILE B CG1 1 
ATOM   2452 C CG2 . ILE B 1 55  ? 13.12592  -46.60538 40.87290  1.000 35.93030  ? 15  ILE B CG2 1 
ATOM   2453 C CD1 . ILE B 1 55  ? 13.45484  -44.22848 42.67214  1.000 44.59685  ? 15  ILE B CD1 1 
ATOM   2454 N N   . GLY B 1 56  ? 15.25465  -49.14780 42.70125  1.000 58.43366  ? 16  GLY B N   1 
ATOM   2455 C CA  . GLY B 1 56  ? 15.67682  -50.49726 42.38722  1.000 55.56197  ? 16  GLY B CA  1 
ATOM   2456 C C   . GLY B 1 56  ? 16.97180  -50.87795 43.07297  1.000 60.68941  ? 16  GLY B C   1 
ATOM   2457 O O   . GLY B 1 56  ? 18.01493  -50.26106 42.83541  1.000 59.50233  ? 16  GLY B O   1 
ATOM   2458 N N   . TYR B 1 57  ? 16.91986  -51.89723 43.92283  1.000 63.50781  ? 17  TYR B N   1 
ATOM   2459 C CA  . TYR B 1 57  ? 18.06002  -52.30137 44.73443  1.000 63.50240  ? 17  TYR B CA  1 
ATOM   2460 C C   . TYR B 1 57  ? 18.61264  -53.62184 44.20689  1.000 67.31444  ? 17  TYR B C   1 
ATOM   2461 O O   . TYR B 1 57  ? 18.45508  -54.68341 44.81354  1.000 72.76460  ? 17  TYR B O   1 
ATOM   2462 C CB  . TYR B 1 57  ? 17.65222  -52.40630 46.20578  1.000 61.50466  ? 17  TYR B CB  1 
ATOM   2463 C CG  . TYR B 1 57  ? 18.82310  -52.35774 47.15386  1.000 61.68627  ? 17  TYR B CG  1 
ATOM   2464 C CD1 . TYR B 1 57  ? 19.57403  -51.20023 47.29453  1.000 52.75822  ? 17  TYR B CD1 1 
ATOM   2465 C CD2 . TYR B 1 57  ? 19.17820  -53.46753 47.90984  1.000 66.12846  ? 17  TYR B CD2 1 
ATOM   2466 C CE1 . TYR B 1 57  ? 20.64843  -51.14725 48.15718  1.000 56.69142  ? 17  TYR B CE1 1 
ATOM   2467 C CE2 . TYR B 1 57  ? 20.25175  -53.42334 48.78005  1.000 65.12017  ? 17  TYR B CE2 1 
ATOM   2468 C CZ  . TYR B 1 57  ? 20.98234  -52.26045 48.89772  1.000 60.25054  ? 17  TYR B CZ  1 
ATOM   2469 O OH  . TYR B 1 57  ? 22.05206  -52.20708 49.75620  1.000 59.40926  ? 17  TYR B OH  1 
ATOM   2470 N N   . GLY B 1 58  ? 19.27108  -53.54111 43.05966  1.000 69.00279  ? 18  GLY B N   1 
ATOM   2471 C CA  . GLY B 1 58  ? 20.01336  -54.63850 42.47727  1.000 58.72553  ? 18  GLY B CA  1 
ATOM   2472 C C   . GLY B 1 58  ? 21.50025  -54.50912 42.72595  1.000 61.24558  ? 18  GLY B C   1 
ATOM   2473 O O   . GLY B 1 58  ? 21.93753  -53.97331 43.75091  1.000 66.19418  ? 18  GLY B O   1 
ATOM   2474 N N   . ASN B 1 59  ? 22.29497  -55.00693 41.77560  1.000 54.02382  ? 19  ASN B N   1 
ATOM   2475 C CA  . ASN B 1 59  ? 23.74344  -54.85195 41.87678  1.000 59.49089  ? 19  ASN B CA  1 
ATOM   2476 C C   . ASN B 1 59  ? 24.13997  -53.38276 41.81974  1.000 58.15105  ? 19  ASN B C   1 
ATOM   2477 O O   . ASN B 1 59  ? 24.92230  -52.90529 42.64948  1.000 64.60973  ? 19  ASN B O   1 
ATOM   2478 C CB  . ASN B 1 59  ? 24.43801  -55.63445 40.76215  1.000 53.35252  ? 19  ASN B CB  1 
ATOM   2479 C CG  . ASN B 1 59  ? 25.29070  -56.76604 41.29200  1.000 72.88805  ? 19  ASN B CG  1 
ATOM   2480 O OD1 . ASN B 1 59  ? 25.10984  -57.92186 40.91618  1.000 85.25366  ? 19  ASN B OD1 1 
ATOM   2481 N ND2 . ASN B 1 59  ? 26.22400  -56.43863 42.17861  1.000 63.67939  ? 19  ASN B ND2 1 
ATOM   2482 N N   . ILE B 1 60  ? 23.61471  -52.65263 40.83312  1.000 52.16957  ? 20  ILE B N   1 
ATOM   2483 C CA  . ILE B 1 60  ? 23.92034  -51.23075 40.70510  1.000 57.98751  ? 20  ILE B CA  1 
ATOM   2484 C C   . ILE B 1 60  ? 23.41918  -50.46748 41.92478  1.000 61.68923  ? 20  ILE B C   1 
ATOM   2485 O O   . ILE B 1 60  ? 24.09979  -49.57007 42.43803  1.000 53.47033  ? 20  ILE B O   1 
ATOM   2486 C CB  . ILE B 1 60  ? 23.32202  -50.67174 39.40009  1.000 61.57018  ? 20  ILE B CB  1 
ATOM   2487 C CG1 . ILE B 1 60  ? 23.91294  -51.38876 38.18224  1.000 47.58913  ? 20  ILE B CG1 1 
ATOM   2488 C CG2 . ILE B 1 60  ? 23.56708  -49.17249 39.29732  1.000 54.90966  ? 20  ILE B CG2 1 
ATOM   2489 C CD1 . ILE B 1 60  ? 25.38905  -51.16922 37.99110  1.000 55.37978  ? 20  ILE B CD1 1 
ATOM   2490 N N   . GLY B 1 61  ? 22.22523  -50.81849 42.41140  1.000 56.37364  ? 21  GLY B N   1 
ATOM   2491 C CA  . GLY B 1 61  ? 21.65018  -50.10306 43.53997  1.000 55.04841  ? 21  GLY B CA  1 
ATOM   2492 C C   . GLY B 1 61  ? 22.46371  -50.23568 44.81274  1.000 56.64062  ? 21  GLY B C   1 
ATOM   2493 O O   . GLY B 1 61  ? 22.58899  -49.27762 45.57899  1.000 53.71265  ? 21  GLY B O   1 
ATOM   2494 N N   . GLN B 1 62  ? 23.02906  -51.42191 45.05679  1.000 56.01386  ? 22  GLN B N   1 
ATOM   2495 C CA  . GLN B 1 62  ? 23.85440  -51.60924 46.24670  1.000 54.58493  ? 22  GLN B CA  1 
ATOM   2496 C C   . GLN B 1 62  ? 25.08998  -50.71913 46.20436  1.000 53.44277  ? 22  GLN B C   1 
ATOM   2497 O O   . GLN B 1 62  ? 25.46659  -50.11940 47.21811  1.000 46.85196  ? 22  GLN B O   1 
ATOM   2498 C CB  . GLN B 1 62  ? 24.24665  -53.08015 46.39794  1.000 65.76797  ? 22  GLN B CB  1 
ATOM   2499 C CG  . GLN B 1 62  ? 23.07194  -53.99516 46.71894  1.000 73.28863  ? 22  GLN B CG  1 
ATOM   2500 C CD  . GLN B 1 62  ? 23.35745  -55.45539 46.42903  1.000 75.96427  ? 22  GLN B CD  1 
ATOM   2501 O OE1 . GLN B 1 62  ? 24.50952  -55.85485 46.26084  1.000 74.99494  ? 22  GLN B OE1 1 
ATOM   2502 N NE2 . GLN B 1 62  ? 22.30364  -56.26190 46.36963  1.000 61.96197  ? 22  GLN B NE2 1 
ATOM   2503 N N   . TYR B 1 63  ? 25.73658  -50.62283 45.04040  1.000 52.34201  ? 23  TYR B N   1 
ATOM   2504 C CA  . TYR B 1 63  ? 26.90296  -49.75453 44.91400  1.000 52.90359  ? 23  TYR B CA  1 
ATOM   2505 C C   . TYR B 1 63  ? 26.50088  -48.28421 44.89239  1.000 52.97670  ? 23  TYR B C   1 
ATOM   2506 O O   . TYR B 1 63  ? 27.22091  -47.43122 45.42623  1.000 52.28881  ? 23  TYR B O   1 
ATOM   2507 C CB  . TYR B 1 63  ? 27.69007  -50.10916 43.65261  1.000 56.40984  ? 23  TYR B CB  1 
ATOM   2508 C CG  . TYR B 1 63  ? 28.48511  -51.38782 43.75032  1.000 52.57361  ? 23  TYR B CG  1 
ATOM   2509 C CD1 . TYR B 1 63  ? 29.78139  -51.38380 44.24234  1.000 46.18243  ? 23  TYR B CD1 1 
ATOM   2510 C CD2 . TYR B 1 63  ? 27.94289  -52.59797 43.34253  1.000 50.24504  ? 23  TYR B CD2 1 
ATOM   2511 C CE1 . TYR B 1 63  ? 30.51632  -52.54974 44.32921  1.000 48.63653  ? 23  TYR B CE1 1 
ATOM   2512 C CE2 . TYR B 1 63  ? 28.66946  -53.76882 43.42709  1.000 44.26543  ? 23  TYR B CE2 1 
ATOM   2513 C CZ  . TYR B 1 63  ? 29.95662  -53.73875 43.91955  1.000 42.65520  ? 23  TYR B CZ  1 
ATOM   2514 O OH  . TYR B 1 63  ? 30.68515  -54.90147 44.00609  1.000 43.39226  ? 23  TYR B OH  1 
ATOM   2515 N N   . ALA B 1 64  ? 25.36079  -47.96965 44.26858  1.000 44.93411  ? 24  ALA B N   1 
ATOM   2516 C CA  . ALA B 1 64  ? 24.86821  -46.59390 44.25053  1.000 47.39051  ? 24  ALA B CA  1 
ATOM   2517 C C   . ALA B 1 64  ? 24.67144  -46.05111 45.65979  1.000 46.93362  ? 24  ALA B C   1 
ATOM   2518 O O   . ALA B 1 64  ? 24.89614  -44.86115 45.91055  1.000 53.04370  ? 24  ALA B O   1 
ATOM   2519 C CB  . ALA B 1 64  ? 23.56398  -46.51056 43.45540  1.000 42.74907  ? 24  ALA B CB  1 
ATOM   2520 N N   . LEU B 1 65  ? 24.22567  -46.90368 46.58453  1.000 46.43729  ? 25  LEU B N   1 
ATOM   2521 C CA  . LEU B 1 65  ? 24.08776  -46.50251 47.98117  1.000 48.99927  ? 25  LEU B CA  1 
ATOM   2522 C C   . LEU B 1 65  ? 25.39864  -45.95417 48.53038  1.000 58.14542  ? 25  LEU B C   1 
ATOM   2523 O O   . LEU B 1 65  ? 25.42432  -44.91401 49.19837  1.000 65.10739  ? 25  LEU B O   1 
ATOM   2524 C CB  . LEU B 1 65  ? 23.61433  -47.69239 48.81477  1.000 52.89295  ? 25  LEU B CB  1 
ATOM   2525 C CG  . LEU B 1 65  ? 23.21009  -47.40643 50.25998  1.000 56.87429  ? 25  LEU B CG  1 
ATOM   2526 C CD1 . LEU B 1 65  ? 21.72148  -47.14375 50.32819  1.000 67.92270  ? 25  LEU B CD1 1 
ATOM   2527 C CD2 . LEU B 1 65  ? 23.59703  -48.55768 51.17337  1.000 77.50910  ? 25  LEU B CD2 1 
ATOM   2528 N N   . GLN B 1 66  ? 26.50128  -46.65555 48.26164  1.000 59.37075  ? 26  GLN B N   1 
ATOM   2529 C CA  . GLN B 1 66  ? 27.80456  -46.22158 48.75135  1.000 50.71097  ? 26  GLN B CA  1 
ATOM   2530 C C   . GLN B 1 66  ? 28.24400  -44.92378 48.08313  1.000 59.36067  ? 26  GLN B C   1 
ATOM   2531 O O   . GLN B 1 66  ? 28.85627  -44.06447 48.72802  1.000 65.72214  ? 26  GLN B O   1 
ATOM   2532 C CB  . GLN B 1 66  ? 28.82916  -47.33210 48.52829  1.000 50.36327  ? 26  GLN B CB  1 
ATOM   2533 C CG  . GLN B 1 66  ? 28.39001  -48.67049 49.10669  1.000 53.60556  ? 26  GLN B CG  1 
ATOM   2534 C CD  . GLN B 1 66  ? 29.31790  -49.80783 48.73477  1.000 49.64964  ? 26  GLN B CD  1 
ATOM   2535 O OE1 . GLN B 1 66  ? 30.03938  -49.73476 47.73895  1.000 59.34682  ? 26  GLN B OE1 1 
ATOM   2536 N NE2 . GLN B 1 66  ? 29.29690  -50.87250 49.52827  1.000 48.14422  ? 26  GLN B NE2 1 
ATOM   2537 N N   . ALA B 1 67  ? 27.95190  -44.76732 46.78909  1.000 54.23335  ? 27  ALA B N   1 
ATOM   2538 C CA  . ALA B 1 67  ? 28.34207  -43.54855 46.08594  1.000 52.47926  ? 27  ALA B CA  1 
ATOM   2539 C C   . ALA B 1 67  ? 27.62182  -42.32567 46.64505  1.000 53.34070  ? 27  ALA B C   1 
ATOM   2540 O O   . ALA B 1 67  ? 28.22309  -41.25404 46.78666  1.000 65.12675  ? 27  ALA B O   1 
ATOM   2541 C CB  . ALA B 1 67  ? 28.07042  -43.69834 44.58944  1.000 46.86899  ? 27  ALA B CB  1 
ATOM   2542 N N   . VAL B 1 68  ? 26.32990  -42.46161 46.95630  1.000 57.28668  ? 28  VAL B N   1 
ATOM   2543 C CA  . VAL B 1 68  ? 25.58392  -41.34866 47.53950  1.000 55.82704  ? 28  VAL B CA  1 
ATOM   2544 C C   . VAL B 1 68  ? 26.13466  -40.99523 48.91514  1.000 58.79126  ? 28  VAL B C   1 
ATOM   2545 O O   . VAL B 1 68  ? 26.29321  -39.81456 49.25105  1.000 64.95403  ? 28  VAL B O   1 
ATOM   2546 C CB  . VAL B 1 68  ? 24.08148  -41.68143 47.59904  1.000 48.96597  ? 28  VAL B CB  1 
ATOM   2547 C CG1 . VAL B 1 68  ? 23.33285  -40.62923 48.40568  1.000 45.40391  ? 28  VAL B CG1 1 
ATOM   2548 C CG2 . VAL B 1 68  ? 23.50902  -41.78394 46.19636  1.000 47.42740  ? 28  VAL B CG2 1 
ATOM   2549 N N   . GLU B 1 69  ? 26.42742  -42.00836 49.73635  1.000 53.33941  ? 29  GLU B N   1 
ATOM   2550 C CA  . GLU B 1 69  ? 26.93780  -41.74037 51.07783  1.000 49.95122  ? 29  GLU B CA  1 
ATOM   2551 C C   . GLU B 1 69  ? 28.25034  -40.97006 51.02703  1.000 54.76710  ? 29  GLU B C   1 
ATOM   2552 O O   . GLU B 1 69  ? 28.45228  -40.02054 51.79329  1.000 62.32927  ? 29  GLU B O   1 
ATOM   2553 C CB  . GLU B 1 69  ? 27.11852  -43.04419 51.85372  1.000 50.82817  ? 29  GLU B CB  1 
ATOM   2554 C CG  . GLU B 1 69  ? 27.57641  -42.82484 53.29281  1.000 65.51403  ? 29  GLU B CG  1 
ATOM   2555 C CD  . GLU B 1 69  ? 27.98713  -44.10738 53.98829  1.000 83.56511  ? 29  GLU B CD  1 
ATOM   2556 O OE1 . GLU B 1 69  ? 27.64367  -45.19819 53.48599  1.000 82.41579  ? 29  GLU B OE1 1 
ATOM   2557 O OE2 . GLU B 1 69  ? 28.65750  -44.02489 55.03826  1.000 79.92621  ? 29  GLU B OE2 1 
ATOM   2558 N N   . GLU B 1 70  ? 29.15847  -41.36695 50.13537  1.000 53.59960  ? 30  GLU B N   1 
ATOM   2559 C CA  . GLU B 1 70  ? 30.44561  -40.69126 50.04898  1.000 66.63436  ? 30  GLU B CA  1 
ATOM   2560 C C   . GLU B 1 70  ? 30.34169  -39.32197 49.39214  1.000 57.20343  ? 30  GLU B C   1 
ATOM   2561 O O   . GLU B 1 70  ? 31.21153  -38.47506 49.62285  1.000 61.48128  ? 30  GLU B O   1 
ATOM   2562 C CB  . GLU B 1 70  ? 31.45062  -41.56677 49.30329  1.000 58.79608  ? 30  GLU B CB  1 
ATOM   2563 C CG  . GLU B 1 70  ? 31.83350  -42.80399 50.08221  1.000 52.95213  ? 30  GLU B CG  1 
ATOM   2564 C CD  . GLU B 1 70  ? 32.39832  -42.46772 51.44648  1.000 63.33181  ? 30  GLU B CD  1 
ATOM   2565 O OE1 . GLU B 1 70  ? 33.17202  -41.49143 51.55342  1.000 60.43235  ? 30  GLU B OE1 1 
ATOM   2566 O OE2 . GLU B 1 70  ? 32.05598  -43.17387 52.41573  1.000 61.41797  ? 30  GLU B OE2 1 
ATOM   2567 N N   . ALA B 1 71  ? 29.31926  -39.09201 48.57621  1.000 58.55802  ? 31  ALA B N   1 
ATOM   2568 C CA  . ALA B 1 71  ? 29.12358  -37.78888 47.95680  1.000 53.33295  ? 31  ALA B CA  1 
ATOM   2569 C C   . ALA B 1 71  ? 28.91229  -36.72826 49.03326  1.000 60.87324  ? 31  ALA B C   1 
ATOM   2570 O O   . ALA B 1 71  ? 27.92802  -36.81031 49.78776  1.000 55.24044  ? 31  ALA B O   1 
ATOM   2571 C CB  . ALA B 1 71  ? 27.92924  -37.82337 47.00663  1.000 47.67598  ? 31  ALA B CB  1 
ATOM   2572 N N   . PRO B 1 72  ? 29.79487  -35.72848 49.14617  1.000 57.26281  ? 32  PRO B N   1 
ATOM   2573 C CA  . PRO B 1 72  ? 29.62308  -34.71041 50.19490  1.000 52.85908  ? 32  PRO B CA  1 
ATOM   2574 C C   . PRO B 1 72  ? 28.49078  -33.73854 49.91841  1.000 58.90330  ? 32  PRO B C   1 
ATOM   2575 O O   . PRO B 1 72  ? 28.06302  -33.03401 50.84322  1.000 58.08768  ? 32  PRO B O   1 
ATOM   2576 C CB  . PRO B 1 72  ? 30.97648  -33.99117 50.20572  1.000 47.61706  ? 32  PRO B CB  1 
ATOM   2577 C CG  . PRO B 1 72  ? 31.46245  -34.12453 48.80313  1.000 50.94521  ? 32  PRO B CG  1 
ATOM   2578 C CD  . PRO B 1 72  ? 31.01540  -35.49748 48.35273  1.000 58.12733  ? 32  PRO B CD  1 
ATOM   2579 N N   . ASP B 1 73  ? 27.99105  -33.68469 48.68602  1.000 54.90374  ? 33  ASP B N   1 
ATOM   2580 C CA  . ASP B 1 73  ? 26.90271  -32.79761 48.30570  1.000 49.60250  ? 33  ASP B CA  1 
ATOM   2581 C C   . ASP B 1 73  ? 25.56970  -33.52340 48.17987  1.000 55.86766  ? 33  ASP B C   1 
ATOM   2582 O O   . ASP B 1 73  ? 24.61561  -32.95580 47.63892  1.000 54.45407  ? 33  ASP B O   1 
ATOM   2583 C CB  . ASP B 1 73  ? 27.24526  -32.09088 46.99307  1.000 43.51609  ? 33  ASP B CB  1 
ATOM   2584 C CG  . ASP B 1 73  ? 27.71061  -33.05471 45.91735  1.000 60.59881  ? 33  ASP B CG  1 
ATOM   2585 O OD1 . ASP B 1 73  ? 28.16012  -34.16510 46.26815  1.000 58.21755  ? 33  ASP B OD1 1 
ATOM   2586 O OD2 . ASP B 1 73  ? 27.63481  -32.70293 44.72194  1.000 50.83671  ? 33  ASP B OD2 1 
ATOM   2587 N N   . MET B 1 74  ? 25.48453  -34.76537 48.65274  1.000 48.24572  ? 34  MET B N   1 
ATOM   2588 C CA  . MET B 1 74  ? 24.27396  -35.56147 48.52071  1.000 55.91124  ? 34  MET B CA  1 
ATOM   2589 C C   . MET B 1 74  ? 23.98401  -36.28368 49.82652  1.000 50.32394  ? 34  MET B C   1 
ATOM   2590 O O   . MET B 1 74  ? 24.89954  -36.68612 50.54919  1.000 65.76787  ? 34  MET B O   1 
ATOM   2591 C CB  . MET B 1 74  ? 24.38425  -36.59066 47.38770  1.000 52.29470  ? 34  MET B CB  1 
ATOM   2592 C CG  . MET B 1 74  ? 24.48025  -35.98499 46.00256  1.000 61.96336  ? 34  MET B CG  1 
ATOM   2593 S SD  . MET B 1 74  ? 24.89666  -37.21632 44.75770  1.000 47.61644  ? 34  MET B SD  1 
ATOM   2594 C CE  . MET B 1 74  ? 25.88407  -36.23781 43.62540  1.000 52.48993  ? 34  MET B CE  1 
ATOM   2595 N N   . GLU B 1 75  ? 22.69567  -36.43583 50.12343  1.000 53.67375  ? 35  GLU B N   1 
ATOM   2596 C CA  . GLU B 1 75  ? 22.23805  -37.27427 51.21915  1.000 68.82250  ? 35  GLU B CA  1 
ATOM   2597 C C   . GLU B 1 75  ? 21.15999  -38.20760 50.68710  1.000 69.12878  ? 35  GLU B C   1 
ATOM   2598 O O   . GLU B 1 75  ? 20.41419  -37.85927 49.76747  1.000 60.94121  ? 35  GLU B O   1 
ATOM   2599 C CB  . GLU B 1 75  ? 21.71445  -36.44530 52.40652  1.000 60.18763  ? 35  GLU B CB  1 
ATOM   2600 C CG  . GLU B 1 75  ? 20.29845  -35.91535 52.26720  1.000 60.38469  ? 35  GLU B CG  1 
ATOM   2601 C CD  . GLU B 1 75  ? 19.80767  -35.24142 53.53487  1.000 79.97301  ? 35  GLU B CD  1 
ATOM   2602 O OE1 . GLU B 1 75  ? 20.19736  -35.68331 54.63580  1.000 79.04096  ? 35  GLU B OE1 1 
ATOM   2603 O OE2 . GLU B 1 75  ? 19.02985  -34.27070 53.42986  1.000 80.49495  ? 35  GLU B OE2 1 
ATOM   2604 N N   . LEU B 1 76  ? 21.09476  -39.40566 51.25909  1.000 47.69890  ? 36  LEU B N   1 
ATOM   2605 C CA  . LEU B 1 76  ? 20.19140  -40.43629 50.76315  1.000 53.55615  ? 36  LEU B CA  1 
ATOM   2606 C C   . LEU B 1 76  ? 18.76102  -40.14061 51.19368  1.000 60.74082  ? 36  LEU B C   1 
ATOM   2607 O O   . LEU B 1 76  ? 18.46760  -40.06944 52.39193  1.000 63.34307  ? 36  LEU B O   1 
ATOM   2608 C CB  . LEU B 1 76  ? 20.61965  -41.80925 51.27128  1.000 56.51092  ? 36  LEU B CB  1 
ATOM   2609 C CG  . LEU B 1 76  ? 19.71527  -42.95938 50.82921  1.000 65.27325  ? 36  LEU B CG  1 
ATOM   2610 C CD1 . LEU B 1 76  ? 19.74762  -43.12687 49.31211  1.000 52.79898  ? 36  LEU B CD1 1 
ATOM   2611 C CD2 . LEU B 1 76  ? 20.10501  -44.24166 51.54355  1.000 60.49992  ? 36  LEU B CD2 1 
ATOM   2612 N N   . ALA B 1 77  ? 17.86995  -39.97633 50.21495  1.000 57.39960  ? 37  ALA B N   1 
ATOM   2613 C CA  . ALA B 1 77  ? 16.45320  -39.81837 50.52147  1.000 52.40302  ? 37  ALA B CA  1 
ATOM   2614 C C   . ALA B 1 77  ? 15.81141  -41.15086 50.89204  1.000 63.16180  ? 37  ALA B C   1 
ATOM   2615 O O   . ALA B 1 77  ? 14.93758  -41.20050 51.76446  1.000 56.53520  ? 37  ALA B O   1 
ATOM   2616 C CB  . ALA B 1 77  ? 15.72478  -39.18163 49.33772  1.000 47.05827  ? 37  ALA B CB  1 
ATOM   2617 N N   . GLY B 1 78  ? 16.22704  -42.22776 50.25052  1.000 57.87838  ? 38  GLY B N   1 
ATOM   2618 C CA  . GLY B 1 78  ? 15.63876  -43.52931 50.49444  1.000 58.25784  ? 38  GLY B CA  1 
ATOM   2619 C C   . GLY B 1 78  ? 15.78949  -44.41553 49.27582  1.000 63.79032  ? 38  GLY B C   1 
ATOM   2620 O O   . GLY B 1 78  ? 16.34779  -44.02354 48.25520  1.000 60.40369  ? 38  GLY B O   1 
ATOM   2621 N N   . VAL B 1 79  ? 15.27065  -45.63353 49.40885  1.000 61.83699  ? 39  VAL B N   1 
ATOM   2622 C CA  . VAL B 1 79  ? 15.33292  -46.64052 48.35711  1.000 52.81883  ? 39  VAL B CA  1 
ATOM   2623 C C   . VAL B 1 79  ? 13.91228  -47.04986 48.00092  1.000 57.25031  ? 39  VAL B C   1 
ATOM   2624 O O   . VAL B 1 79  ? 13.10493  -47.34623 48.88888  1.000 67.16206  ? 39  VAL B O   1 
ATOM   2625 C CB  . VAL B 1 79  ? 16.16355  -47.86308 48.78914  1.000 54.15819  ? 39  VAL B CB  1 
ATOM   2626 C CG1 . VAL B 1 79  ? 16.22762  -48.89036 47.66864  1.000 51.39041  ? 39  VAL B CG1 1 
ATOM   2627 C CG2 . VAL B 1 79  ? 17.56130  -47.43242 49.20107  1.000 55.50535  ? 39  VAL B CG2 1 
ATOM   2628 N N   . VAL B 1 80  ? 13.60971  -47.06264 46.70635  1.000 54.88801  ? 40  VAL B N   1 
ATOM   2629 C CA  . VAL B 1 80  ? 12.30284  -47.46344 46.19869  1.000 58.40857  ? 40  VAL B CA  1 
ATOM   2630 C C   . VAL B 1 80  ? 12.44789  -48.84716 45.58126  1.000 63.24148  ? 40  VAL B C   1 
ATOM   2631 O O   . VAL B 1 80  ? 13.28671  -49.05564 44.69555  1.000 63.68684  ? 40  VAL B O   1 
ATOM   2632 C CB  . VAL B 1 80  ? 11.75554  -46.45497 45.17656  1.000 60.36767  ? 40  VAL B CB  1 
ATOM   2633 C CG1 . VAL B 1 80  ? 10.43743  -46.94702 44.59731  1.000 47.49568  ? 40  VAL B CG1 1 
ATOM   2634 C CG2 . VAL B 1 80  ? 11.58701  -45.08401 45.81718  1.000 57.53676  ? 40  VAL B CG2 1 
ATOM   2635 N N   . ARG B 1 81  ? 11.63210  -49.79050 46.04568  1.000 64.91021  ? 41  ARG B N   1 
ATOM   2636 C CA  . ARG B 1 81  ? 11.64752  -51.16096 45.55670  1.000 58.22522  ? 41  ARG B CA  1 
ATOM   2637 C C   . ARG B 1 81  ? 10.23735  -51.58333 45.16948  1.000 68.88027  ? 41  ARG B C   1 
ATOM   2638 O O   . ARG B 1 81  ? 9.24949   -50.91957 45.49690  1.000 76.15847  ? 41  ARG B O   1 
ATOM   2639 C CB  . ARG B 1 81  ? 12.20788  -52.13134 46.60657  1.000 57.69340  ? 41  ARG B CB  1 
ATOM   2640 C CG  . ARG B 1 81  ? 13.45920  -51.64309 47.31458  1.000 67.44750  ? 41  ARG B CG  1 
ATOM   2641 C CD  . ARG B 1 81  ? 14.08999  -52.75213 48.13935  1.000 63.78798  ? 41  ARG B CD  1 
ATOM   2642 N NE  . ARG B 1 81  ? 14.53787  -53.86017 47.30570  1.000 68.42030  ? 41  ARG B NE  1 
ATOM   2643 C CZ  . ARG B 1 81  ? 15.20270  -54.91597 47.75380  1.000 62.98887  ? 41  ARG B CZ  1 
ATOM   2644 N NH1 . ARG B 1 81  ? 15.50553  -55.05047 49.03494  1.000 56.96261  ? 41  ARG B NH1 1 
ATOM   2645 N NH2 . ARG B 1 81  ? 15.57136  -55.86143 46.89469  1.000 68.44838  ? 41  ARG B NH2 1 
ATOM   2646 N N   . ARG B 1 82  ? 10.15626  -52.70254 44.45393  1.000 67.30292  ? 42  ARG B N   1 
ATOM   2647 C CA  . ARG B 1 82  ? 8.87014   -53.33441 44.19900  1.000 71.87403  ? 42  ARG B CA  1 
ATOM   2648 C C   . ARG B 1 82  ? 8.24615   -53.79748 45.51087  1.000 73.66623  ? 42  ARG B C   1 
ATOM   2649 O O   . ARG B 1 82  ? 8.94299   -54.08514 46.48787  1.000 74.55993  ? 42  ARG B O   1 
ATOM   2650 C CB  . ARG B 1 82  ? 9.03650   -54.53360 43.26379  1.000 68.82205  ? 42  ARG B CB  1 
ATOM   2651 C CG  . ARG B 1 82  ? 9.50425   -54.20611 41.85777  1.000 67.67684  ? 42  ARG B CG  1 
ATOM   2652 C CD  . ARG B 1 82  ? 10.00900  -55.46776 41.17933  1.000 72.63166  ? 42  ARG B CD  1 
ATOM   2653 N NE  . ARG B 1 82  ? 11.16855  -56.00284 41.88255  1.000 70.77194  ? 42  ARG B NE  1 
ATOM   2654 C CZ  . ARG B 1 82  ? 11.77847  -57.13914 41.57656  1.000 64.19542  ? 42  ARG B CZ  1 
ATOM   2655 N NH1 . ARG B 1 82  ? 11.34874  -57.91168 40.59198  1.000 68.92126  ? 42  ARG B NH1 1 
ATOM   2656 N NH2 . ARG B 1 82  ? 12.84571  -57.51058 42.27802  1.000 64.41945  ? 42  ARG B NH2 1 
ATOM   2657 N N   . GLN B 1 83  ? 6.91269   -53.86236 45.53084  1.000 72.65046  ? 43  GLN B N   1 
ATOM   2658 C CA  . GLN B 1 83  ? 6.22003   -54.34498 46.72235  1.000 71.64485  ? 43  GLN B CA  1 
ATOM   2659 C C   . GLN B 1 83  ? 6.61361   -55.78183 47.04023  1.000 72.97687  ? 43  GLN B C   1 
ATOM   2660 O O   . GLN B 1 83  ? 6.69071   -56.16889 48.21261  1.000 76.43355  ? 43  GLN B O   1 
ATOM   2661 C CB  . GLN B 1 83  ? 4.70711   -54.23271 46.53961  1.000 70.19203  ? 43  GLN B CB  1 
ATOM   2662 C CG  . GLN B 1 83  ? 3.91337   -54.57834 47.78871  1.000 64.78162  ? 43  GLN B CG  1 
ATOM   2663 C CD  . GLN B 1 83  ? 4.19066   -53.62693 48.93599  1.000 83.95126  ? 43  GLN B CD  1 
ATOM   2664 O OE1 . GLN B 1 83  ? 4.05686   -52.41101 48.79566  1.000 67.13070  ? 43  GLN B OE1 1 
ATOM   2665 N NE2 . GLN B 1 83  ? 4.58089   -54.17670 50.07948  1.000 89.21320  ? 43  GLN B NE2 1 
ATOM   2666 N N   . SER B 1 84  ? 6.84017   -56.59329 46.00463  1.000 64.04566  ? 44  SER B N   1 
ATOM   2667 C CA  . SER B 1 84  ? 7.29282   -57.96340 46.21683  1.000 65.86541  ? 44  SER B CA  1 
ATOM   2668 C C   . SER B 1 84  ? 8.59709   -57.99978 47.00221  1.000 76.23587  ? 44  SER B C   1 
ATOM   2669 O O   . SER B 1 84  ? 8.77671   -58.84741 47.88411  1.000 85.04949  ? 44  SER B O   1 
ATOM   2670 C CB  . SER B 1 84  ? 7.46361   -58.66932 44.87271  1.000 73.51445  ? 44  SER B CB  1 
ATOM   2671 O OG  . SER B 1 84  ? 6.90186   -57.90588 43.82108  1.000 90.42853  ? 44  SER B OG  1 
ATOM   2672 N N   . SER B 1 85  ? 9.52850   -57.10029 46.68213  1.000 85.66948  ? 45  SER B N   1 
ATOM   2673 C CA  . SER B 1 85  ? 10.81392  -57.07013 47.36657  1.000 81.20687  ? 45  SER B CA  1 
ATOM   2674 C C   . SER B 1 85  ? 10.74370  -56.42672 48.74521  1.000 75.98784  ? 45  SER B C   1 
ATOM   2675 O O   . SER B 1 85  ? 11.65319  -56.63552 49.55608  1.000 73.87836  ? 45  SER B O   1 
ATOM   2676 C CB  . SER B 1 85  ? 11.84679  -56.33314 46.51120  1.000 73.80621  ? 45  SER B CB  1 
ATOM   2677 O OG  . SER B 1 85  ? 12.02866  -56.97242 45.25889  1.000 79.48777  ? 45  SER B OG  1 
ATOM   2678 N N   . LEU B 1 86  ? 9.69318   -55.65450 49.03275  1.000 76.76518  ? 46  LEU B N   1 
ATOM   2679 C CA  . LEU B 1 86  ? 9.60778   -54.98148 50.32339  1.000 80.45102  ? 46  LEU B CA  1 
ATOM   2680 C C   . LEU B 1 86  ? 9.32037   -55.94213 51.46560  1.000 81.62062  ? 46  LEU B C   1 
ATOM   2681 O O   . LEU B 1 86  ? 9.61185   -55.61701 52.62191  1.000 78.12618  ? 46  LEU B O   1 
ATOM   2682 C CB  . LEU B 1 86  ? 8.52605   -53.90477 50.28555  1.000 80.86529  ? 46  LEU B CB  1 
ATOM   2683 C CG  . LEU B 1 86  ? 8.91301   -52.55912 49.67617  1.000 80.90039  ? 46  LEU B CG  1 
ATOM   2684 C CD1 . LEU B 1 86  ? 7.73103   -51.61350 49.72494  1.000 67.13994  ? 46  LEU B CD1 1 
ATOM   2685 C CD2 . LEU B 1 86  ? 10.10629  -51.96385 50.40087  1.000 76.89375  ? 46  LEU B CD2 1 
ATOM   2686 N N   . GLU B 1 87  ? 8.76414   -57.11246 51.16923  1.000 85.77770  ? 47  GLU B N   1 
ATOM   2687 C CA  . GLU B 1 87  ? 8.41063   -58.08734 52.18769  1.000 89.19057  ? 47  GLU B CA  1 
ATOM   2688 C C   . GLU B 1 87  ? 9.45415   -59.18781 52.35524  1.000 76.02406  ? 47  GLU B C   1 
ATOM   2689 O O   . GLU B 1 87  ? 9.30829   -60.02478 53.25248  1.000 93.29451  ? 47  GLU B O   1 
ATOM   2690 C CB  . GLU B 1 87  ? 7.02421   -58.66566 51.87925  1.000 85.51670  ? 47  GLU B CB  1 
ATOM   2691 C CG  . GLU B 1 87  ? 5.98038   -57.55459 51.71879  1.000 91.03932  ? 47  GLU B CG  1 
ATOM   2692 C CD  . GLU B 1 87  ? 4.71555   -58.00087 51.02375  1.000 102.40306 ? 47  GLU B CD  1 
ATOM   2693 O OE1 . GLU B 1 87  ? 4.72403   -59.08237 50.40278  1.000 107.58086 ? 47  GLU B OE1 1 
ATOM   2694 O OE2 . GLU B 1 87  ? 3.71570   -57.25462 51.08281  1.000 100.91243 ? 47  GLU B OE2 1 
ATOM   2695 N N   . LYS B 1 88  ? 10.49802  -59.20709 51.52730  1.000 76.28568  ? 48  LYS B N   1 
ATOM   2696 C CA  . LYS B 1 88  ? 11.64533  -60.04531 51.81776  1.000 79.87018  ? 48  LYS B CA  1 
ATOM   2697 C C   . LYS B 1 88  ? 12.39887  -59.45450 53.00908  1.000 76.24543  ? 48  LYS B C   1 
ATOM   2698 O O   . LYS B 1 88  ? 12.21042  -58.28341 53.34552  1.000 68.41397  ? 48  LYS B O   1 
ATOM   2699 C CB  . LYS B 1 88  ? 12.56300  -60.14383 50.60085  1.000 74.42999  ? 48  LYS B CB  1 
ATOM   2700 C CG  . LYS B 1 88  ? 11.92536  -60.73375 49.35787  1.000 78.52360  ? 48  LYS B CG  1 
ATOM   2701 C CD  . LYS B 1 88  ? 12.91306  -60.71217 48.19564  1.000 96.82013  ? 48  LYS B CD  1 
ATOM   2702 C CE  . LYS B 1 88  ? 13.47286  -59.31607 47.94552  1.000 86.96429  ? 48  LYS B CE  1 
ATOM   2703 N NZ  . LYS B 1 88  ? 14.47325  -59.28820 46.83689  1.000 77.05270  ? 48  LYS B NZ  1 
ATOM   2704 N N   . PRO B 1 89  ? 13.23363  -60.24988 53.68523  1.000 73.57017  ? 49  PRO B N   1 
ATOM   2705 C CA  . PRO B 1 89  ? 13.93325  -59.73136 54.86848  1.000 70.11323  ? 49  PRO B CA  1 
ATOM   2706 C C   . PRO B 1 89  ? 14.75063  -58.49403 54.53312  1.000 73.41540  ? 49  PRO B C   1 
ATOM   2707 O O   . PRO B 1 89  ? 15.31447  -58.37288 53.44378  1.000 66.09422  ? 49  PRO B O   1 
ATOM   2708 C CB  . PRO B 1 89  ? 14.82328  -60.90333 55.29893  1.000 71.44093  ? 49  PRO B CB  1 
ATOM   2709 C CG  . PRO B 1 89  ? 14.12289  -62.10723 54.77168  1.000 70.71910  ? 49  PRO B CG  1 
ATOM   2710 C CD  . PRO B 1 89  ? 13.50255  -61.68402 53.47698  1.000 69.31926  ? 49  PRO B CD  1 
ATOM   2711 N N   . LEU B 1 90  ? 14.79479  -57.56980 55.48060  1.000 70.58147  ? 50  LEU B N   1 
ATOM   2712 C CA  . LEU B 1 90  ? 15.45074  -56.28848 55.26195  1.000 67.06228  ? 50  LEU B CA  1 
ATOM   2713 C C   . LEU B 1 90  ? 16.95502  -56.48670 55.14907  1.000 71.72980  ? 50  LEU B C   1 
ATOM   2714 O O   . LEU B 1 90  ? 17.56698  -57.04247 56.07128  1.000 77.12443  ? 50  LEU B O   1 
ATOM   2715 C CB  . LEU B 1 90  ? 15.12282  -55.33300 56.40674  1.000 69.07083  ? 50  LEU B CB  1 
ATOM   2716 C CG  . LEU B 1 90  ? 15.81326  -53.96676 56.42216  1.000 73.43439  ? 50  LEU B CG  1 
ATOM   2717 C CD1 . LEU B 1 90  ? 15.26543  -53.06338 55.33096  1.000 69.28620  ? 50  LEU B CD1 1 
ATOM   2718 C CD2 . LEU B 1 90  ? 15.66788  -53.30582 57.78344  1.000 75.09196  ? 50  LEU B CD2 1 
ATOM   2719 N N   . PRO B 1 91  ? 17.58364  -56.07584 54.04698  1.000 72.31235  ? 51  PRO B N   1 
ATOM   2720 C CA  . PRO B 1 91  ? 19.04089  -56.20454 53.93881  1.000 68.41920  ? 51  PRO B CA  1 
ATOM   2721 C C   . PRO B 1 91  ? 19.74673  -55.43917 55.04706  1.000 72.24106  ? 51  PRO B C   1 
ATOM   2722 O O   . PRO B 1 91  ? 19.28568  -54.39228 55.50786  1.000 78.44634  ? 51  PRO B O   1 
ATOM   2723 C CB  . PRO B 1 91  ? 19.35616  -55.62265 52.55366  1.000 52.50058  ? 51  PRO B CB  1 
ATOM   2724 C CG  . PRO B 1 91  ? 18.09257  -54.97385 52.08370  1.000 76.29932  ? 51  PRO B CG  1 
ATOM   2725 C CD  . PRO B 1 91  ? 16.96831  -55.65419 52.77996  1.000 73.70007  ? 51  PRO B CD  1 
ATOM   2726 N N   . ARG B 1 92  ? 20.88573  -55.98603 55.47221  1.000 69.93341  ? 52  ARG B N   1 
ATOM   2727 C CA  . ARG B 1 92  ? 21.54002  -55.50191 56.68111  1.000 70.31398  ? 52  ARG B CA  1 
ATOM   2728 C C   . ARG B 1 92  ? 22.05912  -54.07620 56.52966  1.000 77.96879  ? 52  ARG B C   1 
ATOM   2729 O O   . ARG B 1 92  ? 22.09500  -53.32845 57.51268  1.000 78.60995  ? 52  ARG B O   1 
ATOM   2730 C CB  . ARG B 1 92  ? 22.67391  -56.45716 57.05159  1.000 76.73049  ? 52  ARG B CB  1 
ATOM   2731 C CG  . ARG B 1 92  ? 23.38414  -56.14808 58.35190  1.000 84.30039  ? 52  ARG B CG  1 
ATOM   2732 C CD  . ARG B 1 92  ? 24.45141  -57.19322 58.64285  1.000 81.88672  ? 52  ARG B CD  1 
ATOM   2733 N NE  . ARG B 1 92  ? 23.88744  -58.42314 59.18590  1.000 79.14417  ? 52  ARG B NE  1 
ATOM   2734 C CZ  . ARG B 1 92  ? 23.60214  -59.49896 58.46473  1.000 94.82257  ? 52  ARG B CZ  1 
ATOM   2735 N NH1 . ARG B 1 92  ? 23.82109  -59.53492 57.16033  1.000 104.79020 ? 52  ARG B NH1 1 
ATOM   2736 N NH2 . ARG B 1 92  ? 23.08360  -60.56554 59.06729  1.000 78.68519  ? 52  ARG B NH2 1 
ATOM   2737 N N   . GLU B 1 93  ? 22.44513  -53.67196 55.31917  1.000 76.15759  ? 53  GLU B N   1 
ATOM   2738 C CA  . GLU B 1 93  ? 22.95746  -52.32261 55.10876  1.000 71.53265  ? 53  GLU B CA  1 
ATOM   2739 C C   . GLU B 1 93  ? 21.86283  -51.26984 54.96695  1.000 70.63115  ? 53  GLU B C   1 
ATOM   2740 O O   . GLU B 1 93  ? 22.17614  -50.07452 54.98690  1.000 71.77909  ? 53  GLU B O   1 
ATOM   2741 C CB  . GLU B 1 93  ? 23.86968  -52.28644 53.87977  1.000 59.40006  ? 53  GLU B CB  1 
ATOM   2742 C CG  . GLU B 1 93  ? 23.16582  -52.56867 52.57109  1.000 66.27964  ? 53  GLU B CG  1 
ATOM   2743 C CD  . GLU B 1 93  ? 23.03641  -54.05006 52.27732  1.000 67.05122  ? 53  GLU B CD  1 
ATOM   2744 O OE1 . GLU B 1 93  ? 23.28816  -54.86581 53.18949  1.000 70.33255  ? 53  GLU B OE1 1 
ATOM   2745 O OE2 . GLU B 1 93  ? 22.68168  -54.39806 51.13155  1.000 65.27276  ? 53  GLU B OE2 1 
ATOM   2746 N N   . LEU B 1 94  ? 20.60130  -51.66922 54.81764  1.000 73.74392  ? 54  LEU B N   1 
ATOM   2747 C CA  . LEU B 1 94  ? 19.50186  -50.71893 54.70902  1.000 70.20917  ? 54  LEU B CA  1 
ATOM   2748 C C   . LEU B 1 94  ? 18.82975  -50.43906 56.04631  1.000 69.90991  ? 54  LEU B C   1 
ATOM   2749 O O   . LEU B 1 94  ? 17.75521  -49.82985 56.07011  1.000 70.34609  ? 54  LEU B O   1 
ATOM   2750 C CB  . LEU B 1 94  ? 18.46195  -51.20624 53.69494  1.000 56.83804  ? 54  LEU B CB  1 
ATOM   2751 C CG  . LEU B 1 94  ? 18.91631  -51.23707 52.23451  1.000 56.26087  ? 54  LEU B CG  1 
ATOM   2752 C CD1 . LEU B 1 94  ? 17.75884  -51.58753 51.31175  1.000 56.19526  ? 54  LEU B CD1 1 
ATOM   2753 C CD2 . LEU B 1 94  ? 19.54070  -49.91035 51.83351  1.000 60.72504  ? 54  LEU B CD2 1 
ATOM   2754 N N   . HIS B 1 95  ? 19.42808  -50.88183 57.14997  1.000 78.67234  ? 55  HIS B N   1 
ATOM   2755 C CA  . HIS B 1 95  ? 18.90838  -50.55642 58.47085  1.000 85.30740  ? 55  HIS B CA  1 
ATOM   2756 C C   . HIS B 1 95  ? 18.98397  -49.05368 58.70565  1.000 75.75110  ? 55  HIS B C   1 
ATOM   2757 O O   . HIS B 1 95  ? 20.03706  -48.43483 58.52535  1.000 74.59115  ? 55  HIS B O   1 
ATOM   2758 C CB  . HIS B 1 95  ? 19.69344  -51.30651 59.54841  1.000 80.58052  ? 55  HIS B CB  1 
ATOM   2759 C CG  . HIS B 1 95  ? 19.28454  -52.73822 59.70726  1.000 97.08998  ? 55  HIS B CG  1 
ATOM   2760 N ND1 . HIS B 1 95  ? 19.58010  -53.70585 58.77069  1.000 101.19813 ? 55  HIS B ND1 1 
ATOM   2761 C CD2 . HIS B 1 95  ? 18.60850  -53.36750 60.69748  1.000 101.25836 ? 55  HIS B CD2 1 
ATOM   2762 C CE1 . HIS B 1 95  ? 19.09804  -54.86799 59.17411  1.000 92.26440  ? 55  HIS B CE1 1 
ATOM   2763 N NE2 . HIS B 1 95  ? 18.50465  -54.69026 60.34075  1.000 99.81581  ? 55  HIS B NE2 1 
ATOM   2764 N N   . GLY B 1 96  ? 17.86207  -48.46815 59.11427  1.000 68.41013  ? 56  GLY B N   1 
ATOM   2765 C CA  . GLY B 1 96  ? 17.78473  -47.03168 59.26583  1.000 66.26874  ? 56  GLY B CA  1 
ATOM   2766 C C   . GLY B 1 96  ? 17.57761  -46.27311 57.97655  1.000 65.32913  ? 56  GLY B C   1 
ATOM   2767 O O   . GLY B 1 96  ? 17.64568  -45.03832 57.98360  1.000 75.26606  ? 56  GLY B O   1 
ATOM   2768 N N   . VAL B 1 97  ? 17.31897  -46.97071 56.87382  1.000 57.11337  ? 57  VAL B N   1 
ATOM   2769 C CA  . VAL B 1 97  ? 17.10569  -46.36172 55.56745  1.000 55.86516  ? 57  VAL B CA  1 
ATOM   2770 C C   . VAL B 1 97  ? 15.64413  -46.54505 55.19244  1.000 62.05032  ? 57  VAL B C   1 
ATOM   2771 O O   . VAL B 1 97  ? 15.10213  -47.65162 55.30522  1.000 63.05676  ? 57  VAL B O   1 
ATOM   2772 C CB  . VAL B 1 97  ? 18.02717  -46.97884 54.50161  1.000 60.42293  ? 57  VAL B CB  1 
ATOM   2773 C CG1 . VAL B 1 97  ? 17.65775  -46.46783 53.11654  1.000 48.67303  ? 57  VAL B CG1 1 
ATOM   2774 C CG2 . VAL B 1 97  ? 19.48056  -46.67298 54.82362  1.000 58.28596  ? 57  VAL B CG2 1 
ATOM   2775 N N   . SER B 1 98  ? 15.00470  -45.46224 54.75899  1.000 62.00767  ? 58  SER B N   1 
ATOM   2776 C CA  . SER B 1 98  ? 13.61890  -45.53488 54.31216  1.000 61.90680  ? 58  SER B CA  1 
ATOM   2777 C C   . SER B 1 98  ? 13.55273  -46.36244 53.03558  1.000 58.00821  ? 58  SER B C   1 
ATOM   2778 O O   . SER B 1 98  ? 14.03360  -45.93467 51.98201  1.000 57.75819  ? 58  SER B O   1 
ATOM   2779 C CB  . SER B 1 98  ? 13.05942  -44.13391 54.08397  1.000 53.98936  ? 58  SER B CB  1 
ATOM   2780 O OG  . SER B 1 98  ? 13.13840  -43.35051 55.26182  1.000 71.56853  ? 58  SER B OG  1 
ATOM   2781 N N   . VAL B 1 99  ? 12.96031  -47.54716 53.12581  1.000 61.41126  ? 59  VAL B N   1 
ATOM   2782 C CA  . VAL B 1 99  ? 12.78539  -48.43686 51.98511  1.000 58.14348  ? 59  VAL B CA  1 
ATOM   2783 C C   . VAL B 1 99  ? 11.28805  -48.54375 51.74054  1.000 56.50093  ? 59  VAL B C   1 
ATOM   2784 O O   . VAL B 1 99  ? 10.56093  -49.15404 52.53363  1.000 73.76053  ? 59  VAL B O   1 
ATOM   2785 C CB  . VAL B 1 99  ? 13.41608  -49.81447 52.22819  1.000 52.60938  ? 59  VAL B CB  1 
ATOM   2786 C CG1 . VAL B 1 99  ? 13.39370  -50.63924 50.95477  1.000 46.54930  ? 59  VAL B CG1 1 
ATOM   2787 C CG2 . VAL B 1 99  ? 14.84091  -49.66539 52.74170  1.000 48.12957  ? 59  VAL B CG2 1 
ATOM   2788 N N   . VAL B 1 100 ? 10.82581  -47.95710 50.63953  1.000 55.37185  ? 60  VAL B N   1 
ATOM   2789 C CA  . VAL B 1 100 ? 9.41060   -47.79941 50.35442  1.000 61.73837  ? 60  VAL B CA  1 
ATOM   2790 C C   . VAL B 1 100 ? 9.12488   -48.31655 48.94771  1.000 64.81371  ? 60  VAL B C   1 
ATOM   2791 O O   . VAL B 1 100 ? 10.01936  -48.76797 48.23372  1.000 57.14006  ? 60  VAL B O   1 
ATOM   2792 C CB  . VAL B 1 100 ? 8.95185   -46.33511 50.50310  1.000 54.17918  ? 60  VAL B CB  1 
ATOM   2793 C CG1 . VAL B 1 100 ? 9.21008   -45.84145 51.91569  1.000 47.11202  ? 60  VAL B CG1 1 
ATOM   2794 C CG2 . VAL B 1 100 ? 9.69158   -45.46685 49.50846  1.000 62.15017  ? 60  VAL B CG2 1 
ATOM   2795 N N   . SER B 1 101 ? 7.85315   -48.23353 48.55414  1.000 63.30374  ? 61  SER B N   1 
ATOM   2796 C CA  . SER B 1 101 ? 7.40070   -48.71603 47.25713  1.000 61.90842  ? 61  SER B CA  1 
ATOM   2797 C C   . SER B 1 101 ? 7.18120   -47.60052 46.24500  1.000 63.08438  ? 61  SER B C   1 
ATOM   2798 O O   . SER B 1 101 ? 7.02207   -47.89200 45.05441  1.000 67.67526  ? 61  SER B O   1 
ATOM   2799 C CB  . SER B 1 101 ? 6.09862   -49.51347 47.41322  1.000 59.42681  ? 61  SER B CB  1 
ATOM   2800 O OG  . SER B 1 101 ? 5.03476   -48.67017 47.82057  1.000 59.40386  ? 61  SER B OG  1 
ATOM   2801 N N   . ASP B 1 102 ? 7.17971   -46.34114 46.67863  1.000 58.13519  ? 62  ASP B N   1 
ATOM   2802 C CA  . ASP B 1 102 ? 7.01272   -45.22223 45.76440  1.000 67.41142  ? 62  ASP B CA  1 
ATOM   2803 C C   . ASP B 1 102 ? 7.79851   -44.03057 46.29472  1.000 63.33344  ? 62  ASP B C   1 
ATOM   2804 O O   . ASP B 1 102 ? 7.91669   -43.83405 47.50730  1.000 59.56621  ? 62  ASP B O   1 
ATOM   2805 C CB  . ASP B 1 102 ? 5.53306   -44.86081 45.58452  1.000 60.53814  ? 62  ASP B CB  1 
ATOM   2806 C CG  . ASP B 1 102 ? 5.32238   -43.75687 44.56946  1.000 73.80212  ? 62  ASP B CG  1 
ATOM   2807 O OD1 . ASP B 1 102 ? 5.47934   -44.02486 43.36033  1.000 83.85087  ? 62  ASP B OD1 1 
ATOM   2808 O OD2 . ASP B 1 102 ? 5.00585   -42.62169 44.97668  1.000 69.30896  ? 62  ASP B OD2 1 
ATOM   2809 N N   . VAL B 1 103 ? 8.32935   -43.23018 45.36740  1.000 59.29309  ? 63  VAL B N   1 
ATOM   2810 C CA  . VAL B 1 103 ? 9.19429   -42.11235 45.73063  1.000 66.96703  ? 63  VAL B CA  1 
ATOM   2811 C C   . VAL B 1 103 ? 8.46957   -41.05986 46.56256  1.000 62.91711  ? 63  VAL B C   1 
ATOM   2812 O O   . VAL B 1 103 ? 9.11829   -40.27166 47.25915  1.000 57.31093  ? 63  VAL B O   1 
ATOM   2813 C CB  . VAL B 1 103 ? 9.80869   -41.49235 44.45766  1.000 56.81835  ? 63  VAL B CB  1 
ATOM   2814 C CG1 . VAL B 1 103 ? 8.88589   -40.43020 43.87469  1.000 52.47223  ? 63  VAL B CG1 1 
ATOM   2815 C CG2 . VAL B 1 103 ? 11.18078  -40.91125 44.76224  1.000 56.94464  ? 63  VAL B CG2 1 
ATOM   2816 N N   . SER B 1 104 ? 7.13524   -41.01959 46.50475  1.000 63.74311  ? 64  SER B N   1 
ATOM   2817 C CA  . SER B 1 104 ? 6.38788   -40.00271 47.23687  1.000 66.28865  ? 64  SER B CA  1 
ATOM   2818 C C   . SER B 1 104 ? 6.55430   -40.12490 48.74632  1.000 65.68132  ? 64  SER B C   1 
ATOM   2819 O O   . SER B 1 104 ? 6.36176   -39.13482 49.45982  1.000 67.61982  ? 64  SER B O   1 
ATOM   2820 C CB  . SER B 1 104 ? 4.90554   -40.07767 46.86881  1.000 57.12502  ? 64  SER B CB  1 
ATOM   2821 O OG  . SER B 1 104 ? 4.37055   -41.35871 47.15688  1.000 81.44990  ? 64  SER B OG  1 
ATOM   2822 N N   . ALA B 1 105 ? 6.90475   -41.30728 49.24849  1.000 60.87866  ? 65  ALA B N   1 
ATOM   2823 C CA  . ALA B 1 105 ? 7.06154   -41.52376 50.68147  1.000 58.01446  ? 65  ALA B CA  1 
ATOM   2824 C C   . ALA B 1 105 ? 8.42897   -41.10923 51.20888  1.000 61.91905  ? 65  ALA B C   1 
ATOM   2825 O O   . ALA B 1 105 ? 8.69667   -41.30153 52.40016  1.000 66.99267  ? 65  ALA B O   1 
ATOM   2826 C CB  . ALA B 1 105 ? 6.80867   -42.99474 51.02060  1.000 59.23341  ? 65  ALA B CB  1 
ATOM   2827 N N   . LEU B 1 106 ? 9.29538   -40.55028 50.36712  1.000 66.85090  ? 66  LEU B N   1 
ATOM   2828 C CA  . LEU B 1 106 ? 10.64877  -40.19059 50.76657  1.000 71.29876  ? 66  LEU B CA  1 
ATOM   2829 C C   . LEU B 1 106 ? 10.81743  -38.70009 51.03137  1.000 77.79359  ? 66  LEU B C   1 
ATOM   2830 O O   . LEU B 1 106 ? 11.95042  -38.23727 51.19877  1.000 80.67481  ? 66  LEU B O   1 
ATOM   2831 C CB  . LEU B 1 106 ? 11.64856  -40.64558 49.70108  1.000 64.95674  ? 66  LEU B CB  1 
ATOM   2832 C CG  . LEU B 1 106 ? 11.73629  -42.15883 49.49698  1.000 66.01623  ? 66  LEU B CG  1 
ATOM   2833 C CD1 . LEU B 1 106 ? 12.76610  -42.51287 48.43440  1.000 61.11456  ? 66  LEU B CD1 1 
ATOM   2834 C CD2 . LEU B 1 106 ? 12.05927  -42.84517 50.81428  1.000 54.66849  ? 66  LEU B CD2 1 
ATOM   2835 N N   . GLY B 1 107 ? 9.72583   -37.93833 51.07262  1.000 64.36082  ? 67  GLY B N   1 
ATOM   2836 C CA  . GLY B 1 107 ? 9.88117   -36.50910 51.25100  1.000 64.35179  ? 67  GLY B CA  1 
ATOM   2837 C C   . GLY B 1 107 ? 10.40468  -35.85826 49.98291  1.000 60.25786  ? 67  GLY B C   1 
ATOM   2838 O O   . GLY B 1 107 ? 10.10696  -36.28209 48.86155  1.000 68.20452  ? 67  GLY B O   1 
ATOM   2839 N N   . GLN B 1 108 ? 11.18886  -34.79935 50.16617  1.000 61.12000  ? 68  GLN B N   1 
ATOM   2840 C CA  . GLN B 1 108 ? 11.77471  -34.10706 49.02792  1.000 67.69571  ? 68  GLN B CA  1 
ATOM   2841 C C   . GLN B 1 108 ? 12.80434  -34.99155 48.33940  1.000 62.89551  ? 68  GLN B C   1 
ATOM   2842 O O   . GLN B 1 108 ? 13.73026  -35.50245 48.97676  1.000 57.91852  ? 68  GLN B O   1 
ATOM   2843 C CB  . GLN B 1 108 ? 12.42548  -32.79512 49.46308  1.000 64.60868  ? 68  GLN B CB  1 
ATOM   2844 C CG  . GLN B 1 108 ? 13.37834  -32.21145 48.41560  1.000 64.12331  ? 68  GLN B CG  1 
ATOM   2845 C CD  . GLN B 1 108 ? 12.68269  -31.66943 47.17021  1.000 72.24657  ? 68  GLN B CD  1 
ATOM   2846 O OE1 . GLN B 1 108 ? 11.53656  -32.00973 46.87023  1.000 71.80120  ? 68  GLN B OE1 1 
ATOM   2847 N NE2 . GLN B 1 108 ? 13.39384  -30.83089 46.42622  1.000 81.14037  ? 68  GLN B NE2 1 
ATOM   2848 N N   . VAL B 1 109 ? 12.63678  -35.17487 47.03402  1.000 52.71751  ? 69  VAL B N   1 
ATOM   2849 C CA  . VAL B 1 109 ? 13.55336  -35.95958 46.22001  1.000 62.22688  ? 69  VAL B CA  1 
ATOM   2850 C C   . VAL B 1 109 ? 13.97477  -35.07843 45.05493  1.000 55.66799  ? 69  VAL B C   1 
ATOM   2851 O O   . VAL B 1 109 ? 13.14818  -34.73480 44.20076  1.000 58.21067  ? 69  VAL B O   1 
ATOM   2852 C CB  . VAL B 1 109 ? 12.91803  -37.26375 45.71878  1.000 59.24640  ? 69  VAL B CB  1 
ATOM   2853 C CG1 . VAL B 1 109 ? 13.85232  -37.97023 44.74581  1.000 49.98097  ? 69  VAL B CG1 1 
ATOM   2854 C CG2 . VAL B 1 109 ? 12.56429  -38.17072 46.89354  1.000 56.99588  ? 69  VAL B CG2 1 
ATOM   2855 N N   . ASP B 1 110 ? 15.25466  -34.70554 45.02108  1.000 48.59916  ? 70  ASP B N   1 
ATOM   2856 C CA  . ASP B 1 110 ? 15.76417  -33.90067 43.91656  1.000 47.73382  ? 70  ASP B CA  1 
ATOM   2857 C C   . ASP B 1 110 ? 16.06643  -34.76281 42.69662  1.000 50.66215  ? 70  ASP B C   1 
ATOM   2858 O O   . ASP B 1 110 ? 15.65102  -34.43969 41.57776  1.000 46.44056  ? 70  ASP B O   1 
ATOM   2859 C CB  . ASP B 1 110 ? 17.01333  -33.13270 44.35450  1.000 50.04465  ? 70  ASP B CB  1 
ATOM   2860 C CG  . ASP B 1 110 ? 16.72424  -32.12486 45.44978  1.000 50.39693  ? 70  ASP B CG  1 
ATOM   2861 O OD1 . ASP B 1 110 ? 15.84532  -31.26045 45.24542  1.000 62.08098  ? 70  ASP B OD1 1 
ATOM   2862 O OD2 . ASP B 1 110 ? 17.37139  -32.19817 46.51571  1.000 52.28301  ? 70  ASP B OD2 1 
ATOM   2863 N N   . VAL B 1 111 ? 16.78773  -35.86369 42.89544  1.000 54.03983  ? 71  VAL B N   1 
ATOM   2864 C CA  . VAL B 1 111 ? 17.23751  -36.72323 41.80885  1.000 49.95405  ? 71  VAL B CA  1 
ATOM   2865 C C   . VAL B 1 111 ? 16.88328  -38.16525 42.13934  1.000 47.07757  ? 71  VAL B C   1 
ATOM   2866 O O   . VAL B 1 111 ? 17.04565  -38.61118 43.28103  1.000 53.13191  ? 71  VAL B O   1 
ATOM   2867 C CB  . VAL B 1 111 ? 18.75615  -36.58876 41.56262  1.000 53.53336  ? 71  VAL B CB  1 
ATOM   2868 C CG1 . VAL B 1 111 ? 19.19333  -37.49841 40.42571  1.000 44.28880  ? 71  VAL B CG1 1 
ATOM   2869 C CG2 . VAL B 1 111 ? 19.12948  -35.14109 41.27299  1.000 52.45826  ? 71  VAL B CG2 1 
ATOM   2870 N N   . ALA B 1 112 ? 16.39807  -38.89141 41.13759  1.000 49.19166  ? 72  ALA B N   1 
ATOM   2871 C CA  . ALA B 1 112 ? 16.16344  -40.32403 41.23548  1.000 44.19762  ? 72  ALA B CA  1 
ATOM   2872 C C   . ALA B 1 112 ? 17.17602  -41.05308 40.36409  1.000 52.43982  ? 72  ALA B C   1 
ATOM   2873 O O   . ALA B 1 112 ? 17.27078  -40.78577 39.16116  1.000 54.41975  ? 72  ALA B O   1 
ATOM   2874 C CB  . ALA B 1 112 ? 14.74062  -40.67487 40.80330  1.000 43.34820  ? 72  ALA B CB  1 
ATOM   2875 N N   . VAL B 1 113 ? 17.92120  -41.97548 40.96533  1.000 53.03282  ? 73  VAL B N   1 
ATOM   2876 C CA  . VAL B 1 113 ? 18.93350  -42.75454 40.25973  1.000 46.96957  ? 73  VAL B CA  1 
ATOM   2877 C C   . VAL B 1 113 ? 18.34112  -44.11347 39.91773  1.000 49.83093  ? 73  VAL B C   1 
ATOM   2878 O O   . VAL B 1 113 ? 18.04229  -44.91382 40.81277  1.000 47.25980  ? 73  VAL B O   1 
ATOM   2879 C CB  . VAL B 1 113 ? 20.21095  -42.90985 41.09554  1.000 52.45595  ? 73  VAL B CB  1 
ATOM   2880 C CG1 . VAL B 1 113 ? 21.16528  -43.89063 40.41613  1.000 46.99170  ? 73  VAL B CG1 1 
ATOM   2881 C CG2 . VAL B 1 113 ? 20.87269  -41.55435 41.30522  1.000 42.86246  ? 73  VAL B CG2 1 
ATOM   2882 N N   . LEU B 1 114 ? 18.17878  -44.37910 38.62504  1.000 49.10768  ? 74  LEU B N   1 
ATOM   2883 C CA  . LEU B 1 114 ? 17.42427  -45.53574 38.15248  1.000 51.18107  ? 74  LEU B CA  1 
ATOM   2884 C C   . LEU B 1 114 ? 18.35031  -46.73832 38.01468  1.000 43.77634  ? 74  LEU B C   1 
ATOM   2885 O O   . LEU B 1 114 ? 19.13196  -46.82103 37.06309  1.000 56.95287  ? 74  LEU B O   1 
ATOM   2886 C CB  . LEU B 1 114 ? 16.74764  -45.22199 36.82144  1.000 44.65410  ? 74  LEU B CB  1 
ATOM   2887 C CG  . LEU B 1 114 ? 15.38404  -44.53130 36.82127  1.000 45.74439  ? 74  LEU B CG  1 
ATOM   2888 C CD1 . LEU B 1 114 ? 15.30276  -43.38477 37.81906  1.000 44.17098  ? 74  LEU B CD1 1 
ATOM   2889 C CD2 . LEU B 1 114 ? 15.08495  -44.03678 35.42516  1.000 45.95899  ? 74  LEU B CD2 1 
ATOM   2890 N N   . CYS B 1 115 ? 18.24282  -47.68280 38.94964  1.000 48.83336  ? 75  CYS B N   1 
ATOM   2891 C CA  . CYS B 1 115 ? 19.02785  -48.91066 38.89234  1.000 50.49991  ? 75  CYS B CA  1 
ATOM   2892 C C   . CYS B 1 115 ? 18.12887  -50.09076 38.54712  1.000 53.51089  ? 75  CYS B C   1 
ATOM   2893 O O   . CYS B 1 115 ? 18.20953  -51.15138 39.17607  1.000 59.04581  ? 75  CYS B O   1 
ATOM   2894 C CB  . CYS B 1 115 ? 19.74654  -49.14908 40.22165  1.000 46.98773  ? 75  CYS B CB  1 
ATOM   2895 S SG  . CYS B 1 115 ? 20.50784  -47.66456 40.92252  1.000 56.16123  ? 75  CYS B SG  1 
ATOM   2896 N N   . THR B 1 116 ? 17.28024  -49.90919 37.54751  1.000 57.80545  ? 76  THR B N   1 
ATOM   2897 C CA  . THR B 1 116 ? 16.25888  -50.85569 37.13849  1.000 55.34944  ? 76  THR B CA  1 
ATOM   2898 C C   . THR B 1 116 ? 16.65375  -51.55397 35.84188  1.000 55.20848  ? 76  THR B C   1 
ATOM   2899 O O   . THR B 1 116 ? 17.56403  -51.10947 35.13480  1.000 59.31667  ? 76  THR B O   1 
ATOM   2900 C CB  . THR B 1 116 ? 14.92193  -50.12408 36.96107  1.000 58.25981  ? 76  THR B CB  1 
ATOM   2901 O OG1 . THR B 1 116 ? 15.10700  -48.97470 36.12321  1.000 56.30188  ? 76  THR B OG1 1 
ATOM   2902 C CG2 . THR B 1 116 ? 14.38672  -49.67307 38.31150  1.000 43.61918  ? 76  THR B CG2 1 
ATOM   2903 N N   . PRO B 1 117 ? 15.98708  -52.65883 35.49417  1.000 61.45778  ? 77  PRO B N   1 
ATOM   2904 C CA  . PRO B 1 117 ? 16.32794  -53.34883 34.24392  1.000 57.17510  ? 77  PRO B CA  1 
ATOM   2905 C C   . PRO B 1 117 ? 16.10524  -52.45925 33.02972  1.000 54.11911  ? 77  PRO B C   1 
ATOM   2906 O O   . PRO B 1 117 ? 15.26114  -51.56001 33.03506  1.000 54.49715  ? 77  PRO B O   1 
ATOM   2907 C CB  . PRO B 1 117 ? 15.38692  -54.55921 34.23635  1.000 54.22458  ? 77  PRO B CB  1 
ATOM   2908 C CG  . PRO B 1 117 ? 15.08862  -54.80345 35.67160  1.000 53.67735  ? 77  PRO B CG  1 
ATOM   2909 C CD  . PRO B 1 117 ? 15.05018  -53.44994 36.31395  1.000 61.43797  ? 77  PRO B CD  1 
ATOM   2910 N N   . THR B 1 118 ? 16.89476  -52.72601 31.98422  1.000 53.63683  ? 78  THR B N   1 
ATOM   2911 C CA  . THR B 1 118 ? 16.95201  -51.85044 30.81536  1.000 60.06241  ? 78  THR B CA  1 
ATOM   2912 C C   . THR B 1 118 ? 15.57109  -51.58467 30.22755  1.000 57.98013  ? 78  THR B C   1 
ATOM   2913 O O   . THR B 1 118 ? 15.18468  -50.42997 30.01455  1.000 65.26609  ? 78  THR B O   1 
ATOM   2914 C CB  . THR B 1 118 ? 17.87073  -52.46355 29.75684  1.000 56.10660  ? 78  THR B CB  1 
ATOM   2915 O OG1 . THR B 1 118 ? 19.18769  -52.61786 30.29881  1.000 58.36874  ? 78  THR B OG1 1 
ATOM   2916 C CG2 . THR B 1 118 ? 17.93542  -51.57326 28.53169  1.000 54.96471  ? 78  THR B CG2 1 
ATOM   2917 N N   . TYR B 1 119 ? 14.81427  -52.64635 29.95251  1.000 67.39162  ? 79  TYR B N   1 
ATOM   2918 C CA  . TYR B 1 119 ? 13.53419  -52.48624 29.27511  1.000 67.87416  ? 79  TYR B CA  1 
ATOM   2919 C C   . TYR B 1 119 ? 12.49704  -51.80312 30.15543  1.000 62.14100  ? 79  TYR B C   1 
ATOM   2920 O O   . TYR B 1 119 ? 11.54445  -51.21601 29.63125  1.000 62.88491  ? 79  TYR B O   1 
ATOM   2921 C CB  . TYR B 1 119 ? 13.04888  -53.84536 28.77648  1.000 67.73858  ? 79  TYR B CB  1 
ATOM   2922 C CG  . TYR B 1 119 ? 13.85229  -54.30857 27.58162  1.000 87.90897  ? 79  TYR B CG  1 
ATOM   2923 C CD1 . TYR B 1 119 ? 13.84355  -53.58298 26.39736  1.000 87.17478  ? 79  TYR B CD1 1 
ATOM   2924 C CD2 . TYR B 1 119 ? 14.65436  -55.44008 27.64916  1.000 93.54244  ? 79  TYR B CD2 1 
ATOM   2925 C CE1 . TYR B 1 119 ? 14.58538  -53.98538 25.30390  1.000 95.35754  ? 79  TYR B CE1 1 
ATOM   2926 C CE2 . TYR B 1 119 ? 15.40363  -55.85097 26.55843  1.000 95.91533  ? 79  TYR B CE2 1 
ATOM   2927 C CZ  . TYR B 1 119 ? 15.36454  -55.11883 25.38829  1.000 103.75612 ? 79  TYR B CZ  1 
ATOM   2928 O OH  . TYR B 1 119 ? 16.10496  -55.51768 24.29747  1.000 94.79132  ? 79  TYR B OH  1 
ATOM   2929 N N   . GLU B 1 120 ? 12.65299  -51.87518 31.47338  1.000 59.84951  ? 80  GLU B N   1 
ATOM   2930 C CA  . GLU B 1 120 ? 11.74402  -51.21299 32.39508  1.000 54.02653  ? 80  GLU B CA  1 
ATOM   2931 C C   . GLU B 1 120 ? 12.11339  -49.75740 32.65294  1.000 57.29039  ? 80  GLU B C   1 
ATOM   2932 O O   . GLU B 1 120 ? 11.28926  -49.01374 33.19450  1.000 56.65397  ? 80  GLU B O   1 
ATOM   2933 C CB  . GLU B 1 120 ? 11.72644  -51.96004 33.73336  1.000 62.85270  ? 80  GLU B CB  1 
ATOM   2934 C CG  . GLU B 1 120 ? 10.35298  -52.17213 34.32642  1.000 80.07929  ? 80  GLU B CG  1 
ATOM   2935 C CD  . GLU B 1 120 ? 9.75671   -53.49179 33.90429  1.000 91.90157  ? 80  GLU B CD  1 
ATOM   2936 O OE1 . GLU B 1 120 ? 10.44566  -54.24464 33.18595  1.000 80.07505  ? 80  GLU B OE1 1 
ATOM   2937 O OE2 . GLU B 1 120 ? 8.60260   -53.77566 34.28374  1.000 101.52090 ? 80  GLU B OE2 1 
ATOM   2938 N N   . THR B 1 121 ? 13.31602  -49.33053 32.26273  1.000 56.10741  ? 81  THR B N   1 
ATOM   2939 C CA  . THR B 1 121 ? 13.90325  -48.08870 32.75959  1.000 53.53035  ? 81  THR B CA  1 
ATOM   2940 C C   . THR B 1 121 ? 13.33128  -46.82347 32.11782  1.000 48.23685  ? 81  THR B C   1 
ATOM   2941 O O   . THR B 1 121 ? 13.02229  -45.87163 32.84708  1.000 52.43426  ? 81  THR B O   1 
ATOM   2942 C CB  . THR B 1 121 ? 15.42603  -48.12919 32.58797  1.000 49.37650  ? 81  THR B CB  1 
ATOM   2943 O OG1 . THR B 1 121 ? 15.95763  -49.21855 33.34896  1.000 51.31017  ? 81  THR B OG1 1 
ATOM   2944 C CG2 . THR B 1 121 ? 16.06151  -46.83638 33.07950  1.000 39.41902  ? 81  THR B CG2 1 
ATOM   2945 N N   . PRO B 1 122 ? 13.17781  -46.74578 30.78585  1.000 45.50310  ? 82  PRO B N   1 
ATOM   2946 C CA  . PRO B 1 122 ? 12.61188  -45.51135 30.20909  1.000 47.06205  ? 82  PRO B CA  1 
ATOM   2947 C C   . PRO B 1 122 ? 11.22646  -45.17038 30.73225  1.000 50.06847  ? 82  PRO B C   1 
ATOM   2948 O O   . PRO B 1 122 ? 10.93892  -43.99332 30.98716  1.000 53.00000  ? 82  PRO B O   1 
ATOM   2949 C CB  . PRO B 1 122 ? 12.59161  -45.80953 28.70352  1.000 51.78762  ? 82  PRO B CB  1 
ATOM   2950 C CG  . PRO B 1 122 ? 13.67407  -46.80136 28.50999  1.000 52.75356  ? 82  PRO B CG  1 
ATOM   2951 C CD  . PRO B 1 122 ? 13.60727  -47.67535 29.72449  1.000 50.63158  ? 82  PRO B CD  1 
ATOM   2952 N N   . ALA B 1 123 ? 10.35336  -46.16979 30.89004  1.000 59.22822  ? 83  ALA B N   1 
ATOM   2953 C CA  . ALA B 1 123 ? 9.01038   -45.90870 31.40125  1.000 53.63993  ? 83  ALA B CA  1 
ATOM   2954 C C   . ALA B 1 123 ? 9.05704   -45.40808 32.83929  1.000 47.86703  ? 83  ALA B C   1 
ATOM   2955 O O   . ALA B 1 123 ? 8.32754   -44.47806 33.20376  1.000 57.39611  ? 83  ALA B O   1 
ATOM   2956 C CB  . ALA B 1 123 ? 8.15079   -47.16779 31.28845  1.000 57.40870  ? 83  ALA B CB  1 
ATOM   2957 N N   . ILE B 1 124 ? 9.91078   -46.01155 33.66804  1.000 44.97874  ? 84  ILE B N   1 
ATOM   2958 C CA  . ILE B 1 124 ? 10.09251  -45.52891 35.03332  1.000 52.24488  ? 84  ILE B CA  1 
ATOM   2959 C C   . ILE B 1 124 ? 10.59918  -44.09124 35.02162  1.000 57.38051  ? 84  ILE B C   1 
ATOM   2960 O O   . ILE B 1 124 ? 10.17683  -43.26110 35.83690  1.000 53.01196  ? 84  ILE B O   1 
ATOM   2961 C CB  . ILE B 1 124 ? 11.04051  -46.46542 35.80711  1.000 53.57714  ? 84  ILE B CB  1 
ATOM   2962 C CG1 . ILE B 1 124 ? 10.41105  -47.85249 35.95307  1.000 46.13503  ? 84  ILE B CG1 1 
ATOM   2963 C CG2 . ILE B 1 124 ? 11.39267  -45.87971 37.17010  1.000 42.22477  ? 84  ILE B CG2 1 
ATOM   2964 C CD1 . ILE B 1 124 ? 11.31303  -48.86656 36.60927  1.000 45.51981  ? 84  ILE B CD1 1 
ATOM   2965 N N   . ALA B 1 125 ? 11.51134  -43.77477 34.09607  1.000 50.10037  ? 85  ALA B N   1 
ATOM   2966 C CA  . ALA B 1 125 ? 12.06402  -42.42415 34.01560  1.000 50.41880  ? 85  ALA B CA  1 
ATOM   2967 C C   . ALA B 1 125 ? 10.98180  -41.39686 33.70337  1.000 59.92805  ? 85  ALA B C   1 
ATOM   2968 O O   . ALA B 1 125 ? 10.85672  -40.38282 34.40108  1.000 56.62172  ? 85  ALA B O   1 
ATOM   2969 C CB  . ALA B 1 125 ? 13.17379  -42.37076 32.96448  1.000 52.79984  ? 85  ALA B CB  1 
ATOM   2970 N N   . LYS B 1 126 ? 10.19446  -41.63897 32.64751  1.000 53.91019  ? 86  LYS B N   1 
ATOM   2971 C CA  . LYS B 1 126 ? 9.11037   -40.72210 32.30196  1.000 57.55410  ? 86  LYS B CA  1 
ATOM   2972 C C   . LYS B 1 126 ? 8.16404   -40.50598 33.47737  1.000 55.80353  ? 86  LYS B C   1 
ATOM   2973 O O   . LYS B 1 126 ? 7.63458   -39.40332 33.65713  1.000 69.13227  ? 86  LYS B O   1 
ATOM   2974 C CB  . LYS B 1 126 ? 8.33493   -41.22079 31.07877  1.000 56.25916  ? 86  LYS B CB  1 
ATOM   2975 C CG  . LYS B 1 126 ? 9.09185   -41.17097 29.75990  1.000 47.93933  ? 86  LYS B CG  1 
ATOM   2976 C CD  . LYS B 1 126 ? 8.30705   -41.87897 28.66417  1.000 47.77250  ? 86  LYS B CD  1 
ATOM   2977 C CE  . LYS B 1 126 ? 9.12144   -42.97769 28.01133  1.000 59.50216  ? 86  LYS B CE  1 
ATOM   2978 N NZ  . LYS B 1 126 ? 8.68913   -43.19641 26.60339  1.000 59.53419  ? 86  LYS B NZ  1 
ATOM   2979 N N   . GLU B 1 127 ? 7.91641   -41.54915 34.27467  1.000 53.73121  ? 87  GLU B N   1 
ATOM   2980 C CA  . GLU B 1 127 ? 7.04153   -41.38298 35.43048  1.000 55.80616  ? 87  GLU B CA  1 
ATOM   2981 C C   . GLU B 1 127 ? 7.60673   -40.34039 36.38358  1.000 54.44050  ? 87  GLU B C   1 
ATOM   2982 O O   . GLU B 1 127 ? 6.88139   -39.46827 36.87681  1.000 57.17563  ? 87  GLU B O   1 
ATOM   2983 C CB  . GLU B 1 127 ? 6.87153   -42.70600 36.17586  1.000 57.77525  ? 87  GLU B CB  1 
ATOM   2984 C CG  . GLU B 1 127 ? 5.67402   -42.70398 37.10975  1.000 76.28350  ? 87  GLU B CG  1 
ATOM   2985 C CD  . GLU B 1 127 ? 5.32876   -44.07676 37.64897  1.000 100.58375 ? 87  GLU B CD  1 
ATOM   2986 O OE1 . GLU B 1 127 ? 5.11635   -45.01848 36.85308  1.000 102.52479 ? 87  GLU B OE1 1 
ATOM   2987 O OE2 . GLU B 1 127 ? 5.27258   -44.19803 38.89568  1.000 103.64309 ? 87  GLU B OE2 1 
ATOM   2988 N N   . LEU B 1 128 ? 8.91088   -40.41520 36.64536  1.000 51.82064  ? 88  LEU B N   1 
ATOM   2989 C CA  . LEU B 1 128 ? 9.53711   -39.56177 37.64394  1.000 54.53029  ? 88  LEU B CA  1 
ATOM   2990 C C   . LEU B 1 128 ? 9.81803   -38.16875 37.10080  1.000 56.89170  ? 88  LEU B C   1 
ATOM   2991 O O   . LEU B 1 128 ? 9.73067   -37.18699 37.84849  1.000 48.53440  ? 88  LEU B O   1 
ATOM   2992 C CB  . LEU B 1 128 ? 10.82881  -40.21662 38.13304  1.000 58.66737  ? 88  LEU B CB  1 
ATOM   2993 C CG  . LEU B 1 128 ? 10.61617  -41.44007 39.03264  1.000 42.71844  ? 88  LEU B CG  1 
ATOM   2994 C CD1 . LEU B 1 128 ? 11.91348  -42.20794 39.24197  1.000 46.97276  ? 88  LEU B CD1 1 
ATOM   2995 C CD2 . LEU B 1 128 ? 10.01031  -41.02968 40.35913  1.000 43.19812  ? 88  LEU B CD2 1 
ATOM   2996 N N   . LEU B 1 129 ? 10.16911  -38.06847 35.81519  1.000 53.40098  ? 89  LEU B N   1 
ATOM   2997 C CA  . LEU B 1 129 ? 10.31119  -36.76174 35.18143  1.000 51.65794  ? 89  LEU B CA  1 
ATOM   2998 C C   . LEU B 1 129 ? 9.01542   -35.96405 35.26373  1.000 56.84870  ? 89  LEU B C   1 
ATOM   2999 O O   . LEU B 1 129 ? 9.03725   -34.75317 35.51310  1.000 56.64382  ? 89  LEU B O   1 
ATOM   3000 C CB  . LEU B 1 129 ? 10.74731  -36.92616 33.72531  1.000 53.17178  ? 89  LEU B CB  1 
ATOM   3001 C CG  . LEU B 1 129 ? 12.16958  -37.43612 33.48912  1.000 62.86900  ? 89  LEU B CG  1 
ATOM   3002 C CD1 . LEU B 1 129 ? 12.37337  -37.82532 32.02763  1.000 56.69110  ? 89  LEU B CD1 1 
ATOM   3003 C CD2 . LEU B 1 129 ? 13.19583  -36.39621 33.92702  1.000 48.05290  ? 89  LEU B CD2 1 
ATOM   3004 N N   . ALA B 1 130 ? 7.87518   -36.62488 35.04280  1.000 55.85103  ? 90  ALA B N   1 
ATOM   3005 C CA  . ALA B 1 130 ? 6.59456   -35.92478 35.05610  1.000 49.85570  ? 90  ALA B CA  1 
ATOM   3006 C C   . ALA B 1 130 ? 6.28909   -35.32815 36.42231  1.000 49.49457  ? 90  ALA B C   1 
ATOM   3007 O O   . ALA B 1 130 ? 5.53669   -34.35241 36.51673  1.000 54.05006  ? 90  ALA B O   1 
ATOM   3008 C CB  . ALA B 1 130 ? 5.47363   -36.87030 34.62629  1.000 42.66970  ? 90  ALA B CB  1 
ATOM   3009 N N   . ARG B 1 131 ? 6.85038   -35.89574 37.48740  1.000 49.55627  ? 91  ARG B N   1 
ATOM   3010 C CA  . ARG B 1 131 ? 6.73781   -35.30497 38.81397  1.000 45.85120  ? 91  ARG B CA  1 
ATOM   3011 C C   . ARG B 1 131 ? 7.75343   -34.19534 39.05371  1.000 56.21569  ? 91  ARG B C   1 
ATOM   3012 O O   . ARG B 1 131 ? 7.82433   -33.67421 40.17150  1.000 53.26291  ? 91  ARG B O   1 
ATOM   3013 C CB  . ARG B 1 131 ? 6.89277   -36.37761 39.89537  1.000 57.00080  ? 91  ARG B CB  1 
ATOM   3014 C CG  . ARG B 1 131 ? 5.88873   -37.51191 39.81860  1.000 60.57989  ? 91  ARG B CG  1 
ATOM   3015 C CD  . ARG B 1 131 ? 5.87782   -38.28775 41.12595  1.000 65.75060  ? 91  ARG B CD  1 
ATOM   3016 N NE  . ARG B 1 131 ? 5.54531   -39.69458 40.94072  1.000 79.65413  ? 91  ARG B NE  1 
ATOM   3017 C CZ  . ARG B 1 131 ? 5.38874   -40.56235 41.93119  1.000 78.47315  ? 91  ARG B CZ  1 
ATOM   3018 N NH1 . ARG B 1 131 ? 5.51002   -40.19603 43.19690  1.000 75.89670  ? 91  ARG B NH1 1 
ATOM   3019 N NH2 . ARG B 1 131 ? 5.10593   -41.83000 41.64454  1.000 75.75595  ? 91  ARG B NH2 1 
ATOM   3020 N N   . GLY B 1 132 ? 8.53311   -33.82113 38.04199  1.000 53.31612  ? 92  GLY B N   1 
ATOM   3021 C CA  . GLY B 1 132 ? 9.55357   -32.81043 38.22479  1.000 51.07345  ? 92  GLY B CA  1 
ATOM   3022 C C   . GLY B 1 132 ? 10.82521  -33.29433 38.88250  1.000 55.57653  ? 92  GLY B C   1 
ATOM   3023 O O   . GLY B 1 132 ? 11.62447  -32.47106 39.33921  1.000 60.71516  ? 92  GLY B O   1 
ATOM   3024 N N   . ILE B 1 133 ? 11.04327  -34.60490 38.94701  1.000 49.49555  ? 93  ILE B N   1 
ATOM   3025 C CA  . ILE B 1 133 ? 12.23070  -35.17922 39.56961  1.000 49.02759  ? 93  ILE B CA  1 
ATOM   3026 C C   . ILE B 1 133 ? 13.24381  -35.49999 38.48029  1.000 57.23200  ? 93  ILE B C   1 
ATOM   3027 O O   . ILE B 1 133 ? 12.90042  -36.12120 37.46645  1.000 56.76391  ? 93  ILE B O   1 
ATOM   3028 C CB  . ILE B 1 133 ? 11.88044  -36.44006 40.37906  1.000 60.02151  ? 93  ILE B CB  1 
ATOM   3029 C CG1 . ILE B 1 133 ? 10.80997  -36.13267 41.42916  1.000 49.44316  ? 93  ILE B CG1 1 
ATOM   3030 C CG2 . ILE B 1 133 ? 13.12679  -37.02154 41.03819  1.000 54.89541  ? 93  ILE B CG2 1 
ATOM   3031 C CD1 . ILE B 1 133 ? 10.32045  -37.36377 42.16647  1.000 50.36787  ? 93  ILE B CD1 1 
ATOM   3032 N N   . HIS B 1 134 ? 14.48914  -35.07869 38.68474  1.000 53.45780  ? 94  HIS B N   1 
ATOM   3033 C CA  . HIS B 1 134 ? 15.56092  -35.44454 37.77115  1.000 47.15926  ? 94  HIS B CA  1 
ATOM   3034 C C   . HIS B 1 134 ? 15.83716  -36.94261 37.85060  1.000 50.80110  ? 94  HIS B C   1 
ATOM   3035 O O   . HIS B 1 134 ? 15.68203  -37.57147 38.90127  1.000 50.09052  ? 94  HIS B O   1 
ATOM   3036 C CB  . HIS B 1 134 ? 16.82927  -34.65397 38.09193  1.000 48.39448  ? 94  HIS B CB  1 
ATOM   3037 C CG  . HIS B 1 134 ? 16.62029  -33.17251 38.14286  1.000 55.19807  ? 94  HIS B CG  1 
ATOM   3038 N ND1 . HIS B 1 134 ? 15.75245  -32.51477 37.29842  1.000 57.62780  ? 94  HIS B ND1 1 
ATOM   3039 C CD2 . HIS B 1 134 ? 17.16314  -32.22132 38.93930  1.000 49.48664  ? 94  HIS B CD2 1 
ATOM   3040 C CE1 . HIS B 1 134 ? 15.77144  -31.22222 37.56965  1.000 48.25600  ? 94  HIS B CE1 1 
ATOM   3041 N NE2 . HIS B 1 134 ? 16.61928  -31.01766 38.56150  1.000 48.34420  ? 94  HIS B NE2 1 
ATOM   3042 N N   . THR B 1 135 ? 16.24686  -37.51748 36.72053  1.000 49.57267  ? 95  THR B N   1 
ATOM   3043 C CA  . THR B 1 135 ? 16.49107  -38.95027 36.62349  1.000 61.05965  ? 95  THR B CA  1 
ATOM   3044 C C   . THR B 1 135 ? 17.84233  -39.22744 35.98030  1.000 53.33851  ? 95  THR B C   1 
ATOM   3045 O O   . THR B 1 135 ? 18.21302  -38.59522 34.98654  1.000 51.89610  ? 95  THR B O   1 
ATOM   3046 C CB  . THR B 1 135 ? 15.38775  -39.65701 35.81865  1.000 52.33462  ? 95  THR B CB  1 
ATOM   3047 O OG1 . THR B 1 135 ? 15.36270  -39.14353 34.48080  1.000 61.25439  ? 95  THR B OG1 1 
ATOM   3048 C CG2 . THR B 1 135 ? 14.02910  -39.45540 36.47088  1.000 47.16170  ? 95  THR B CG2 1 
ATOM   3049 N N   . ILE B 1 136 ? 18.56792  -40.18447 36.55529  1.000 48.35720  ? 96  ILE B N   1 
ATOM   3050 C CA  . ILE B 1 136 ? 19.81245  -40.70170 36.00025  1.000 43.74559  ? 96  ILE B CA  1 
ATOM   3051 C C   . ILE B 1 136 ? 19.61476  -42.17976 35.69234  1.000 50.68728  ? 96  ILE B C   1 
ATOM   3052 O O   . ILE B 1 136 ? 19.03308  -42.91536 36.49802  1.000 52.74183  ? 96  ILE B O   1 
ATOM   3053 C CB  . ILE B 1 136 ? 20.99616  -40.50194 36.97125  1.000 48.48390  ? 96  ILE B CB  1 
ATOM   3054 C CG1 . ILE B 1 136 ? 21.03135  -39.06150 37.48564  1.000 48.46396  ? 96  ILE B CG1 1 
ATOM   3055 C CG2 . ILE B 1 136 ? 22.31334  -40.85351 36.29379  1.000 38.09286  ? 96  ILE B CG2 1 
ATOM   3056 C CD1 . ILE B 1 136 ? 21.34081  -38.03973 36.41334  1.000 44.56549  ? 96  ILE B CD1 1 
ATOM   3057 N N   . ASP B 1 137 ? 20.08995  -42.61439 34.52541  1.000 49.38656  ? 97  ASP B N   1 
ATOM   3058 C CA  . ASP B 1 137 ? 20.04202  -44.02428 34.16379  1.000 47.89347  ? 97  ASP B CA  1 
ATOM   3059 C C   . ASP B 1 137 ? 21.28287  -44.39314 33.36204  1.000 56.53607  ? 97  ASP B C   1 
ATOM   3060 O O   . ASP B 1 137 ? 21.99842  -43.52966 32.84747  1.000 56.51142  ? 97  ASP B O   1 
ATOM   3061 C CB  . ASP B 1 137 ? 18.76659  -44.36742 33.37389  1.000 43.67809  ? 97  ASP B CB  1 
ATOM   3062 C CG  . ASP B 1 137 ? 18.73054  -43.72603 31.99797  1.000 58.22610  ? 97  ASP B CG  1 
ATOM   3063 O OD1 . ASP B 1 137 ? 19.49249  -44.16244 31.11142  1.000 60.26472  ? 97  ASP B OD1 1 
ATOM   3064 O OD2 . ASP B 1 137 ? 17.93484  -42.78429 31.80395  1.000 70.48767  ? 97  ASP B OD2 1 
ATOM   3065 N N   . SER B 1 138 ? 21.52677  -45.69802 33.26263  1.000 54.11183  ? 98  SER B N   1 
ATOM   3066 C CA  . SER B 1 138 ? 22.61431  -46.25691 32.46870  1.000 56.16287  ? 98  SER B CA  1 
ATOM   3067 C C   . SER B 1 138 ? 22.07107  -47.15454 31.36121  1.000 55.57039  ? 98  SER B C   1 
ATOM   3068 O O   . SER B 1 138 ? 22.63455  -48.20864 31.05689  1.000 54.51794  ? 98  SER B O   1 
ATOM   3069 C CB  . SER B 1 138 ? 23.60028  -47.01811 33.35154  1.000 49.18561  ? 98  SER B CB  1 
ATOM   3070 O OG  . SER B 1 138 ? 22.93519  -47.98888 34.13803  1.000 63.44585  ? 98  SER B OG  1 
ATOM   3071 N N   . PHE B 1 139 ? 20.94174  -46.74972 30.77692  1.000 51.19099  ? 99  PHE B N   1 
ATOM   3072 C CA  . PHE B 1 139 ? 20.35399  -47.43738 29.63051  1.000 50.00360  ? 99  PHE B CA  1 
ATOM   3073 C C   . PHE B 1 139 ? 21.41473  -47.74444 28.57908  1.000 57.97719  ? 99  PHE B C   1 
ATOM   3074 O O   . PHE B 1 139 ? 22.15717  -46.85654 28.15282  1.000 58.72017  ? 99  PHE B O   1 
ATOM   3075 C CB  . PHE B 1 139 ? 19.24461  -46.56521 29.03932  1.000 44.98692  ? 99  PHE B CB  1 
ATOM   3076 C CG  . PHE B 1 139 ? 18.45562  -47.22576 27.94905  1.000 55.37455  ? 99  PHE B CG  1 
ATOM   3077 C CD1 . PHE B 1 139 ? 17.34549  -47.99944 28.24777  1.000 54.94047  ? 99  PHE B CD1 1 
ATOM   3078 C CD2 . PHE B 1 139 ? 18.80718  -47.05046 26.62088  1.000 59.53584  ? 99  PHE B CD2 1 
ATOM   3079 C CE1 . PHE B 1 139 ? 16.60905  -48.59783 27.24061  1.000 57.08856  ? 99  PHE B CE1 1 
ATOM   3080 C CE2 . PHE B 1 139 ? 18.07614  -47.64655 25.61050  1.000 61.19901  ? 99  PHE B CE2 1 
ATOM   3081 C CZ  . PHE B 1 139 ? 16.97657  -48.42192 25.92102  1.000 62.26924  ? 99  PHE B CZ  1 
ATOM   3082 N N   . ASP B 1 140 ? 21.48239  -49.01304 28.15689  1.000 55.21345  ? 100 ASP B N   1 
ATOM   3083 C CA  . ASP B 1 140 ? 22.63269  -49.49612 27.39898  1.000 59.79302  ? 100 ASP B CA  1 
ATOM   3084 C C   . ASP B 1 140 ? 22.26029  -50.13488 26.06247  1.000 56.71099  ? 100 ASP B C   1 
ATOM   3085 O O   . ASP B 1 140 ? 23.05161  -50.91259 25.51866  1.000 57.41462  ? 100 ASP B O   1 
ATOM   3086 C CB  . ASP B 1 140 ? 23.44960  -50.48202 28.23998  1.000 54.98364  ? 100 ASP B CB  1 
ATOM   3087 C CG  . ASP B 1 140 ? 22.62218  -51.64945 28.74504  1.000 57.38052  ? 100 ASP B CG  1 
ATOM   3088 O OD1 . ASP B 1 140 ? 21.43510  -51.75791 28.36690  1.000 63.61789  ? 100 ASP B OD1 1 
ATOM   3089 O OD2 . ASP B 1 140 ? 23.16621  -52.46599 29.51756  1.000 71.10601  ? 100 ASP B OD2 1 
ATOM   3090 N N   . ILE B 1 141 ? 21.08775  -49.82968 25.51274  1.000 58.35376  ? 101 ILE B N   1 
ATOM   3091 C CA  . ILE B 1 141 ? 20.72355  -50.28755 24.17509  1.000 66.64918  ? 101 ILE B CA  1 
ATOM   3092 C C   . ILE B 1 141 ? 21.10251  -49.16998 23.20740  1.000 68.06777  ? 101 ILE B C   1 
ATOM   3093 O O   . ILE B 1 141 ? 20.37167  -48.18946 23.05368  1.000 65.04803  ? 101 ILE B O   1 
ATOM   3094 C CB  . ILE B 1 141 ? 19.24166  -50.65247 24.07685  1.000 67.61948  ? 101 ILE B CB  1 
ATOM   3095 C CG1 . ILE B 1 141 ? 18.88791  -51.74282 25.09147  1.000 62.72620  ? 101 ILE B CG1 1 
ATOM   3096 C CG2 . ILE B 1 141 ? 18.90596  -51.11888 22.67227  1.000 65.70479  ? 101 ILE B CG2 1 
ATOM   3097 C CD1 . ILE B 1 141 ? 19.53013  -53.08398 24.80906  1.000 78.35760  ? 101 ILE B CD1 1 
ATOM   3098 N N   . HIS B 1 142 ? 22.26549  -49.31641 22.56305  1.000 60.55219  ? 102 HIS B N   1 
ATOM   3099 C CA  . HIS B 1 142 ? 22.80791  -48.24162 21.73481  1.000 61.97639  ? 102 HIS B CA  1 
ATOM   3100 C C   . HIS B 1 142 ? 21.84475  -47.85044 20.62037  1.000 62.87118  ? 102 HIS B C   1 
ATOM   3101 O O   . HIS B 1 142 ? 21.68881  -46.66260 20.31277  1.000 70.86013  ? 102 HIS B O   1 
ATOM   3102 C CB  . HIS B 1 142 ? 24.15764  -48.65941 21.14719  1.000 61.44837  ? 102 HIS B CB  1 
ATOM   3103 C CG  . HIS B 1 142 ? 25.24278  -48.81854 22.16739  1.000 70.06901  ? 102 HIS B CG  1 
ATOM   3104 N ND1 . HIS B 1 142 ? 25.35440  -49.93253 22.97158  1.000 78.81819  ? 102 HIS B ND1 1 
ATOM   3105 C CD2 . HIS B 1 142 ? 26.26803  -48.00359 22.51094  1.000 69.90571  ? 102 HIS B CD2 1 
ATOM   3106 C CE1 . HIS B 1 142 ? 26.40041  -49.79597 23.76722  1.000 75.52525  ? 102 HIS B CE1 1 
ATOM   3107 N NE2 . HIS B 1 142 ? 26.97183  -48.63383 23.50813  1.000 62.85320  ? 102 HIS B NE2 1 
ATOM   3108 N N   . GLN B 1 143 ? 21.18948  -48.83754 20.00474  1.000 62.88477  ? 103 GLN B N   1 
ATOM   3109 C CA  . GLN B 1 143 ? 20.33699  -48.57969 18.85003  1.000 65.14083  ? 103 GLN B CA  1 
ATOM   3110 C C   . GLN B 1 143 ? 19.08359  -47.78362 19.19951  1.000 67.55419  ? 103 GLN B C   1 
ATOM   3111 O O   . GLN B 1 143 ? 18.45407  -47.22102 18.29665  1.000 77.49574  ? 103 GLN B O   1 
ATOM   3112 C CB  . GLN B 1 143 ? 19.95429  -49.90758 18.19520  1.000 79.06095  ? 103 GLN B CB  1 
ATOM   3113 C CG  . GLN B 1 143 ? 21.08529  -50.93011 18.19443  1.000 88.16563  ? 103 GLN B CG  1 
ATOM   3114 C CD  . GLN B 1 143 ? 21.02751  -51.87530 19.37989  1.000 89.59487  ? 103 GLN B CD  1 
ATOM   3115 O OE1 . GLN B 1 143 ? 21.88497  -51.83355 20.26377  1.000 75.39428  ? 103 GLN B OE1 1 
ATOM   3116 N NE2 . GLN B 1 143 ? 20.02288  -52.73958 19.39911  1.000 101.75389 ? 103 GLN B NE2 1 
ATOM   3117 N N   . GLU B 1 144 ? 18.70388  -47.72442 20.47642  1.000 63.28716  ? 104 GLU B N   1 
ATOM   3118 C CA  . GLU B 1 144 ? 17.51103  -47.00529 20.90819  1.000 66.54681  ? 104 GLU B CA  1 
ATOM   3119 C C   . GLU B 1 144 ? 17.80373  -45.72814 21.68046  1.000 67.30671  ? 104 GLU B C   1 
ATOM   3120 O O   . GLU B 1 144 ? 16.86221  -45.08918 22.16130  1.000 67.97031  ? 104 GLU B O   1 
ATOM   3121 C CB  . GLU B 1 144 ? 16.60863  -47.91393 21.74805  1.000 62.35131  ? 104 GLU B CB  1 
ATOM   3122 C CG  . GLU B 1 144 ? 15.90177  -48.97107 20.93299  1.000 73.59593  ? 104 GLU B CG  1 
ATOM   3123 C CD  . GLU B 1 144 ? 14.72623  -48.38562 20.16982  1.000 98.31247  ? 104 GLU B CD  1 
ATOM   3124 O OE1 . GLU B 1 144 ? 13.69004  -48.09573 20.80374  1.000 96.42038  ? 104 GLU B OE1 1 
ATOM   3125 O OE2 . GLU B 1 144 ? 14.84539  -48.19033 18.94247  1.000 104.05299 ? 104 GLU B OE2 1 
ATOM   3126 N N   . ILE B 1 145 ? 19.07066  -45.33645 21.81926  1.000 57.81811  ? 105 ILE B N   1 
ATOM   3127 C CA  . ILE B 1 145 ? 19.39545  -44.18995 22.66341  1.000 51.53102  ? 105 ILE B CA  1 
ATOM   3128 C C   . ILE B 1 145 ? 18.83537  -42.90576 22.06134  1.000 59.10269  ? 105 ILE B C   1 
ATOM   3129 O O   . ILE B 1 145 ? 18.24975  -42.07754 22.76894  1.000 53.11270  ? 105 ILE B O   1 
ATOM   3130 C CB  . ILE B 1 145 ? 20.91493  -44.09853 22.89233  1.000 61.52116  ? 105 ILE B CB  1 
ATOM   3131 C CG1 . ILE B 1 145 ? 21.37240  -45.19885 23.85495  1.000 52.64781  ? 105 ILE B CG1 1 
ATOM   3132 C CG2 . ILE B 1 145 ? 21.30302  -42.72145 23.42489  1.000 52.14309  ? 105 ILE B CG2 1 
ATOM   3133 C CD1 . ILE B 1 145 ? 22.85884  -45.19362 24.12606  1.000 67.84111  ? 105 ILE B CD1 1 
ATOM   3134 N N   . VAL B 1 146 ? 19.01810  -42.71558 20.75073  1.000 54.33899  ? 106 VAL B N   1 
ATOM   3135 C CA  . VAL B 1 146 ? 18.49509  -41.52360 20.08199  1.000 43.54715  ? 106 VAL B CA  1 
ATOM   3136 C C   . VAL B 1 146 ? 16.99473  -41.38721 20.31492  1.000 51.40246  ? 106 VAL B C   1 
ATOM   3137 O O   . VAL B 1 146 ? 16.50102  -40.31649 20.69021  1.000 54.56531  ? 106 VAL B O   1 
ATOM   3138 C CB  . VAL B 1 146 ? 18.82981  -41.55980 18.57981  1.000 53.48416  ? 106 VAL B CB  1 
ATOM   3139 C CG1 . VAL B 1 146 ? 18.05619  -40.47963 17.83386  1.000 40.90601  ? 106 VAL B CG1 1 
ATOM   3140 C CG2 . VAL B 1 146 ? 20.32546  -41.38350 18.37062  1.000 50.45111  ? 106 VAL B CG2 1 
ATOM   3141 N N   . GLN B 1 147 ? 16.24822  -42.47501 20.10215  1.000 63.55314  ? 107 GLN B N   1 
ATOM   3142 C CA  . GLN B 1 147 ? 14.79649  -42.42511 20.26285  1.000 58.02364  ? 107 GLN B CA  1 
ATOM   3143 C C   . GLN B 1 147 ? 14.40748  -42.18023 21.71651  1.000 51.48961  ? 107 GLN B C   1 
ATOM   3144 O O   . GLN B 1 147 ? 13.55848  -41.32904 22.00648  1.000 50.20008  ? 107 GLN B O   1 
ATOM   3145 C CB  . GLN B 1 147 ? 14.15940  -43.71720 19.74403  1.000 63.25634  ? 107 GLN B CB  1 
ATOM   3146 C CG  . GLN B 1 147 ? 12.65305  -43.80194 19.97539  1.000 57.11516  ? 107 GLN B CG  1 
ATOM   3147 C CD  . GLN B 1 147 ? 11.89139  -42.71269 19.23637  1.000 74.42570  ? 107 GLN B CD  1 
ATOM   3148 O OE1 . GLN B 1 147 ? 12.29364  -42.28271 18.15598  1.000 85.03180  ? 107 GLN B OE1 1 
ATOM   3149 N NE2 . GLN B 1 147 ? 10.79270  -42.25165 19.82562  1.000 53.83978  ? 107 GLN B NE2 1 
ATOM   3150 N N   . VAL B 1 148 ? 15.01445  -42.92421 22.64496  1.000 53.05073  ? 108 VAL B N   1 
ATOM   3151 C CA  . VAL B 1 148 ? 14.69367  -42.76050 24.06112  1.000 53.79024  ? 108 VAL B CA  1 
ATOM   3152 C C   . VAL B 1 148 ? 15.04994  -41.35491 24.53197  1.000 58.28337  ? 108 VAL B C   1 
ATOM   3153 O O   . VAL B 1 148 ? 14.32754  -40.75266 25.33677  1.000 56.02668  ? 108 VAL B O   1 
ATOM   3154 C CB  . VAL B 1 148 ? 15.40304  -43.84439 24.89524  1.000 52.30692  ? 108 VAL B CB  1 
ATOM   3155 C CG1 . VAL B 1 148 ? 15.29121  -43.53766 26.38017  1.000 52.29960  ? 108 VAL B CG1 1 
ATOM   3156 C CG2 . VAL B 1 148 ? 14.81578  -45.22127 24.58525  1.000 46.79658  ? 108 VAL B CG2 1 
ATOM   3157 N N   . ARG B 1 149 ? 16.16133  -40.80760 24.02947  1.000 58.84944  ? 109 ARG B N   1 
ATOM   3158 C CA  . ARG B 1 149 ? 16.56334  -39.44853 24.38599  1.000 49.00611  ? 109 ARG B CA  1 
ATOM   3159 C C   . ARG B 1 149 ? 15.48643  -38.43309 24.01907  1.000 52.95356  ? 109 ARG B C   1 
ATOM   3160 O O   . ARG B 1 149 ? 15.14824  -37.55382 24.82051  1.000 54.06765  ? 109 ARG B O   1 
ATOM   3161 C CB  . ARG B 1 149 ? 17.88792  -39.10258 23.70406  1.000 51.89495  ? 109 ARG B CB  1 
ATOM   3162 C CG  . ARG B 1 149 ? 18.42152  -37.71763 24.02878  1.000 52.44717  ? 109 ARG B CG  1 
ATOM   3163 C CD  . ARG B 1 149 ? 19.64846  -37.40258 23.18806  1.000 58.19116  ? 109 ARG B CD  1 
ATOM   3164 N NE  . ARG B 1 149 ? 19.95265  -35.97769 23.16009  1.000 56.26767  ? 109 ARG B NE  1 
ATOM   3165 C CZ  . ARG B 1 149 ? 19.40478  -35.11461 22.31582  1.000 64.74488  ? 109 ARG B CZ  1 
ATOM   3166 N NH1 . ARG B 1 149 ? 18.51223  -35.49848 21.41778  1.000 58.58902  ? 109 ARG B NH1 1 
ATOM   3167 N NH2 . ARG B 1 149 ? 19.76593  -33.83557 22.36951  1.000 62.32227  ? 109 ARG B NH2 1 
ATOM   3168 N N   . HIS B 1 150 ? 14.94387  -38.53162 22.80245  1.000 49.31000  ? 110 HIS B N   1 
ATOM   3169 C CA  . HIS B 1 150 ? 13.88061  -37.61883 22.39021  1.000 54.00162  ? 110 HIS B CA  1 
ATOM   3170 C C   . HIS B 1 150 ? 12.64950  -37.76367 23.27353  1.000 53.73997  ? 110 HIS B C   1 
ATOM   3171 O O   . HIS B 1 150 ? 12.02190  -36.76504 23.64287  1.000 51.04282  ? 110 HIS B O   1 
ATOM   3172 C CB  . HIS B 1 150 ? 13.51027  -37.85743 20.92680  1.000 41.43260  ? 110 HIS B CB  1 
ATOM   3173 C CG  . HIS B 1 150 ? 14.45249  -37.22672 19.95188  1.000 58.74513  ? 110 HIS B CG  1 
ATOM   3174 N ND1 . HIS B 1 150 ? 14.79499  -37.82337 18.75802  1.000 66.80646  ? 110 HIS B ND1 1 
ATOM   3175 C CD2 . HIS B 1 150 ? 15.11034  -36.04396 19.98457  1.000 52.33568  ? 110 HIS B CD2 1 
ATOM   3176 C CE1 . HIS B 1 150 ? 15.63121  -37.04039 18.10165  1.000 47.51238  ? 110 HIS B CE1 1 
ATOM   3177 N NE2 . HIS B 1 150 ? 15.83967  -35.95462 18.82407  1.000 51.05309  ? 110 HIS B NE2 1 
ATOM   3178 N N   . GLU B 1 151 ? 12.27394  -39.00221 23.60203  1.000 48.55848  ? 111 GLU B N   1 
ATOM   3179 C CA  . GLU B 1 151 ? 11.08085  -39.22385 24.41253  1.000 51.12182  ? 111 GLU B CA  1 
ATOM   3180 C C   . GLU B 1 151 ? 11.25998  -38.67602 25.82288  1.000 55.66093  ? 111 GLU B C   1 
ATOM   3181 O O   . GLU B 1 151 ? 10.34808  -38.04533 26.36997  1.000 55.28538  ? 111 GLU B O   1 
ATOM   3182 C CB  . GLU B 1 151 ? 10.74186  -40.71368 24.44494  1.000 49.17592  ? 111 GLU B CB  1 
ATOM   3183 C CG  . GLU B 1 151 ? 10.45895  -41.30435 23.07086  1.000 54.49169  ? 111 GLU B CG  1 
ATOM   3184 C CD  . GLU B 1 151 ? 10.08297  -42.77008 23.12994  1.000 66.06697  ? 111 GLU B CD  1 
ATOM   3185 O OE1 . GLU B 1 151 ? 9.83778   -43.27733 24.24440  1.000 69.44606  ? 111 GLU B OE1 1 
ATOM   3186 O OE2 . GLU B 1 151 ? 10.03382  -43.41578 22.06229  1.000 72.05612  ? 111 GLU B OE2 1 
ATOM   3187 N N   . LEU B 1 152 ? 12.42716  -38.90457 26.42881  1.000 57.46606  ? 112 LEU B N   1 
ATOM   3188 C CA  . LEU B 1 152 ? 12.69163  -38.32537 27.74076  1.000 49.55128  ? 112 LEU B CA  1 
ATOM   3189 C C   . LEU B 1 152 ? 12.79346  -36.80843 27.66568  1.000 53.48652  ? 112 LEU B C   1 
ATOM   3190 O O   . LEU B 1 152 ? 12.42515  -36.11489 28.62063  1.000 49.75384  ? 112 LEU B O   1 
ATOM   3191 C CB  . LEU B 1 152 ? 13.97579  -38.90715 28.33532  1.000 46.99662  ? 112 LEU B CB  1 
ATOM   3192 C CG  . LEU B 1 152 ? 14.07620  -40.41579 28.56877  1.000 51.40712  ? 112 LEU B CG  1 
ATOM   3193 C CD1 . LEU B 1 152 ? 15.30220  -40.72882 29.41360  1.000 38.83969  ? 112 LEU B CD1 1 
ATOM   3194 C CD2 . LEU B 1 152 ? 12.81718  -40.94715 29.22969  1.000 45.49446  ? 112 LEU B CD2 1 
ATOM   3195 N N   . ASP B 1 153 ? 13.29293  -36.28116 26.54582  1.000 50.87813  ? 113 ASP B N   1 
ATOM   3196 C CA  . ASP B 1 153 ? 13.46099  -34.83784 26.40180  1.000 52.25060  ? 113 ASP B CA  1 
ATOM   3197 C C   . ASP B 1 153 ? 12.13241  -34.09776 26.52027  1.000 55.94384  ? 113 ASP B C   1 
ATOM   3198 O O   . ASP B 1 153 ? 12.04152  -33.07301 27.20630  1.000 55.19805  ? 113 ASP B O   1 
ATOM   3199 C CB  . ASP B 1 153 ? 14.12845  -34.53071 25.06121  1.000 48.54132  ? 113 ASP B CB  1 
ATOM   3200 C CG  . ASP B 1 153 ? 14.60886  -33.09828 24.96009  1.000 55.83566  ? 113 ASP B CG  1 
ATOM   3201 O OD1 . ASP B 1 153 ? 15.33780  -32.64277 25.86616  1.000 57.71127  ? 113 ASP B OD1 1 
ATOM   3202 O OD2 . ASP B 1 153 ? 14.25950  -32.42871 23.96705  1.000 71.90272  ? 113 ASP B OD2 1 
ATOM   3203 N N   . GLU B 1 154 ? 11.08988  -34.59343 25.84613  1.000 51.22966  ? 114 GLU B N   1 
ATOM   3204 C CA  . GLU B 1 154 ? 9.82016   -33.87056 25.83471  1.000 59.29809  ? 114 GLU B CA  1 
ATOM   3205 C C   . GLU B 1 154 ? 9.16072   -33.87544 27.20984  1.000 55.13778  ? 114 GLU B C   1 
ATOM   3206 O O   . GLU B 1 154 ? 8.58090   -32.86535 27.62589  1.000 53.19450  ? 114 GLU B O   1 
ATOM   3207 C CB  . GLU B 1 154 ? 8.88143   -34.43475 24.76163  1.000 55.23873  ? 114 GLU B CB  1 
ATOM   3208 C CG  . GLU B 1 154 ? 8.29942   -35.81572 25.01860  1.000 68.25723  ? 114 GLU B CG  1 
ATOM   3209 C CD  . GLU B 1 154 ? 7.17894   -36.14977 24.04879  1.000 75.91904  ? 114 GLU B CD  1 
ATOM   3210 O OE1 . GLU B 1 154 ? 6.59016   -35.20865 23.47447  1.000 75.85936  ? 114 GLU B OE1 1 
ATOM   3211 O OE2 . GLU B 1 154 ? 6.88909   -37.34874 23.85676  1.000 77.36240  ? 114 GLU B OE2 1 
ATOM   3212 N N   . VAL B 1 155 ? 9.23287   -34.99935 27.92740  1.000 46.70932  ? 115 VAL B N   1 
ATOM   3213 C CA  . VAL B 1 155 ? 8.66195   -35.05835 29.26939  1.000 47.95825  ? 115 VAL B CA  1 
ATOM   3214 C C   . VAL B 1 155 ? 9.44116   -34.16061 30.22046  1.000 53.60659  ? 115 VAL B C   1 
ATOM   3215 O O   . VAL B 1 155 ? 8.85475   -33.44474 31.04170  1.000 57.63563  ? 115 VAL B O   1 
ATOM   3216 C CB  . VAL B 1 155 ? 8.62601   -36.51122 29.77422  1.000 49.22280  ? 115 VAL B CB  1 
ATOM   3217 C CG1 . VAL B 1 155 ? 7.87206   -36.58870 31.09472  1.000 36.93112  ? 115 VAL B CG1 1 
ATOM   3218 C CG2 . VAL B 1 155 ? 8.00202   -37.42419 28.72844  1.000 50.54013  ? 115 VAL B CG2 1 
ATOM   3219 N N   . ALA B 1 156 ? 10.77221  -34.19033 30.13154  1.000 58.34337  ? 116 ALA B N   1 
ATOM   3220 C CA  . ALA B 1 156 ? 11.59968  -33.39887 31.03614  1.000 57.04567  ? 116 ALA B CA  1 
ATOM   3221 C C   . ALA B 1 156 ? 11.34209  -31.90777 30.85813  1.000 51.92558  ? 116 ALA B C   1 
ATOM   3222 O O   . ALA B 1 156 ? 11.21823  -31.16445 31.83836  1.000 46.56433  ? 116 ALA B O   1 
ATOM   3223 C CB  . ALA B 1 156 ? 13.07607  -33.72365 30.80896  1.000 50.84167  ? 116 ALA B CB  1 
ATOM   3224 N N   . ARG B 1 157 ? 11.27064  -31.44900 29.60779  1.000 51.74238  ? 117 ARG B N   1 
ATOM   3225 C CA  . ARG B 1 157 ? 11.03788  -30.03095 29.35753  1.000 54.27693  ? 117 ARG B CA  1 
ATOM   3226 C C   . ARG B 1 157 ? 9.65899   -29.59164 29.83139  1.000 61.67566  ? 117 ARG B C   1 
ATOM   3227 O O   . ARG B 1 157 ? 9.48740   -28.44449 30.25670  1.000 57.29398  ? 117 ARG B O   1 
ATOM   3228 C CB  . ARG B 1 157 ? 11.22738  -29.71352 27.87488  1.000 53.05034  ? 117 ARG B CB  1 
ATOM   3229 C CG  . ARG B 1 157 ? 12.67715  -29.80878 27.42498  1.000 48.17915  ? 117 ARG B CG  1 
ATOM   3230 C CD  . ARG B 1 157 ? 13.03418  -28.67706 26.48586  1.000 62.05395  ? 117 ARG B CD  1 
ATOM   3231 N NE  . ARG B 1 157 ? 12.45349  -28.83917 25.16054  1.000 72.69058  ? 117 ARG B NE  1 
ATOM   3232 C CZ  . ARG B 1 157 ? 12.42763  -27.88368 24.24272  1.000 83.07885  ? 117 ARG B CZ  1 
ATOM   3233 N NH1 . ARG B 1 157 ? 12.92743  -26.68277 24.48368  1.000 65.18044  ? 117 ARG B NH1 1 
ATOM   3234 N NH2 . ARG B 1 157 ? 11.88651  -28.13858 23.05475  1.000 85.24700  ? 117 ARG B NH2 1 
ATOM   3235 N N   . ALA B 1 158 ? 8.66482   -30.47551 29.75344  1.000 57.27170  ? 118 ALA B N   1 
ATOM   3236 C CA  . ALA B 1 158 ? 7.31874   -30.11408 30.17634  1.000 50.91840  ? 118 ALA B CA  1 
ATOM   3237 C C   . ALA B 1 158 ? 7.20958   -29.90467 31.68228  1.000 52.25763  ? 118 ALA B C   1 
ATOM   3238 O O   . ALA B 1 158 ? 6.28155   -29.22351 32.13174  1.000 58.31476  ? 118 ALA B O   1 
ATOM   3239 C CB  . ALA B 1 158 ? 6.32597   -31.18705 29.72685  1.000 34.31477  ? 118 ALA B CB  1 
ATOM   3240 N N   . HIS B 1 159 ? 8.12606   -30.47135 32.47394  1.000 47.16464  ? 119 HIS B N   1 
ATOM   3241 C CA  . HIS B 1 159 ? 7.99392   -30.44581 33.92711  1.000 51.26591  ? 119 HIS B CA  1 
ATOM   3242 C C   . HIS B 1 159 ? 9.24981   -29.93717 34.62891  1.000 49.72545  ? 119 HIS B C   1 
ATOM   3243 O O   . HIS B 1 159 ? 9.47021   -30.27183 35.79734  1.000 45.09432  ? 119 HIS B O   1 
ATOM   3244 C CB  . HIS B 1 159 ? 7.61954   -31.83065 34.45997  1.000 49.20680  ? 119 HIS B CB  1 
ATOM   3245 C CG  . HIS B 1 159 ? 6.29623   -32.32611 33.96634  1.000 64.84432  ? 119 HIS B CG  1 
ATOM   3246 N ND1 . HIS B 1 159 ? 6.16701   -33.08569 32.82368  1.000 65.12075  ? 119 HIS B ND1 1 
ATOM   3247 C CD2 . HIS B 1 159 ? 5.04264   -32.15704 34.45015  1.000 48.13029  ? 119 HIS B CD2 1 
ATOM   3248 C CE1 . HIS B 1 159 ? 4.89205   -33.37215 32.63002  1.000 60.59608  ? 119 HIS B CE1 1 
ATOM   3249 N NE2 . HIS B 1 159 ? 4.18889   -32.82037 33.60263  1.000 60.74326  ? 119 HIS B NE2 1 
ATOM   3250 N N   . GLN B 1 160 ? 10.07308  -29.13879 33.94720  1.000 49.84545  ? 120 GLN B N   1 
ATOM   3251 C CA  . GLN B 1 160 ? 11.24849  -28.50964 34.55339  1.000 60.22224  ? 120 GLN B CA  1 
ATOM   3252 C C   . GLN B 1 160 ? 12.17295  -29.54657 35.19420  1.000 55.32781  ? 120 GLN B C   1 
ATOM   3253 O O   . GLN B 1 160 ? 12.66220  -29.37247 36.31257  1.000 54.39331  ? 120 GLN B O   1 
ATOM   3254 C CB  . GLN B 1 160 ? 10.82317  -27.45061 35.57460  1.000 57.98483  ? 120 GLN B CB  1 
ATOM   3255 C CG  . GLN B 1 160 ? 10.26896  -26.18101 34.95177  1.000 72.09901  ? 120 GLN B CG  1 
ATOM   3256 C CD  . GLN B 1 160 ? 11.32372  -25.12253 34.71473  1.000 75.14980  ? 120 GLN B CD  1 
ATOM   3257 O OE1 . GLN B 1 160 ? 11.46500  -24.60932 33.60397  1.000 87.58683  ? 120 GLN B OE1 1 
ATOM   3258 N NE2 . GLN B 1 160 ? 12.05855  -24.77506 35.76232  1.000 61.21608  ? 120 GLN B NE2 1 
ATOM   3259 N N   . ALA B 1 161 ? 12.41498  -30.63625 34.47023  1.000 50.13885  ? 121 ALA B N   1 
ATOM   3260 C CA  . ALA B 1 161 ? 13.24269  -31.72478 34.96388  1.000 55.57569  ? 121 ALA B CA  1 
ATOM   3261 C C   . ALA B 1 161 ? 14.37949  -31.98768 33.98682  1.000 53.52095  ? 121 ALA B C   1 
ATOM   3262 O O   . ALA B 1 161 ? 14.31665  -31.61913 32.81291  1.000 48.78202  ? 121 ALA B O   1 
ATOM   3263 C CB  . ALA B 1 161 ? 12.42319  -33.00657 35.17282  1.000 51.81981  ? 121 ALA B CB  1 
ATOM   3264 N N   . VAL B 1 162 ? 15.42158  -32.64354 34.48907  1.000 51.01063  ? 122 VAL B N   1 
ATOM   3265 C CA  . VAL B 1 162 ? 16.60934  -32.98231 33.71506  1.000 54.33969  ? 122 VAL B CA  1 
ATOM   3266 C C   . VAL B 1 162 ? 16.76524  -34.49524 33.72211  1.000 50.37999  ? 122 VAL B C   1 
ATOM   3267 O O   . VAL B 1 162 ? 16.73723  -35.12169 34.78771  1.000 52.69530  ? 122 VAL B O   1 
ATOM   3268 C CB  . VAL B 1 162 ? 17.86993  -32.30380 34.28060  1.000 43.08995  ? 122 VAL B CB  1 
ATOM   3269 C CG1 . VAL B 1 162 ? 19.10357  -32.75169 33.51055  1.000 42.55256  ? 122 VAL B CG1 1 
ATOM   3270 C CG2 . VAL B 1 162 ? 17.72084  -30.79980 34.23343  1.000 46.35839  ? 122 VAL B CG2 1 
ATOM   3271 N N   . ALA B 1 163 ? 16.92401  -35.07965 32.53978  1.000 46.38621  ? 123 ALA B N   1 
ATOM   3272 C CA  . ALA B 1 163 ? 17.18587  -36.50493 32.40064  1.000 48.58111  ? 123 ALA B CA  1 
ATOM   3273 C C   . ALA B 1 163 ? 18.56977  -36.70986 31.80105  1.000 51.82916  ? 123 ALA B C   1 
ATOM   3274 O O   . ALA B 1 163 ? 18.88965  -36.13632 30.75532  1.000 42.25512  ? 123 ALA B O   1 
ATOM   3275 C CB  . ALA B 1 163 ? 16.12885  -37.17779 31.52296  1.000 45.48887  ? 123 ALA B CB  1 
ATOM   3276 N N   . ILE B 1 164 ? 19.39520  -37.50765 32.47013  1.000 44.36351  ? 124 ILE B N   1 
ATOM   3277 C CA  . ILE B 1 164 ? 20.66730  -37.95562 31.91734  1.000 40.10806  ? 124 ILE B CA  1 
ATOM   3278 C C   . ILE B 1 164 ? 20.57335  -39.46123 31.71862  1.000 43.69123  ? 124 ILE B C   1 
ATOM   3279 O O   . ILE B 1 164 ? 20.40034  -40.21459 32.68556  1.000 50.96613  ? 124 ILE B O   1 
ATOM   3280 C CB  . ILE B 1 164 ? 21.85209  -37.57377 32.81790  1.000 56.21703  ? 124 ILE B CB  1 
ATOM   3281 C CG1 . ILE B 1 164 ? 21.96430  -36.05248 32.92386  1.000 44.47427  ? 124 ILE B CG1 1 
ATOM   3282 C CG2 . ILE B 1 164 ? 23.15009  -38.17031 32.28336  1.000 31.40528  ? 124 ILE B CG2 1 
ATOM   3283 C CD1 . ILE B 1 164 ? 22.90837  -35.58207 34.00465  1.000 48.10398  ? 124 ILE B CD1 1 
ATOM   3284 N N   . LEU B 1 165 ? 20.68778  -39.89784 30.46723  1.000 48.89735  ? 125 LEU B N   1 
ATOM   3285 C CA  . LEU B 1 165 ? 20.52225  -41.29443 30.09824  1.000 46.60494  ? 125 LEU B CA  1 
ATOM   3286 C C   . LEU B 1 165 ? 21.82658  -41.85744 29.55017  1.000 47.33148  ? 125 LEU B C   1 
ATOM   3287 O O   . LEU B 1 165 ? 22.71404  -41.11650 29.11622  1.000 47.95048  ? 125 LEU B O   1 
ATOM   3288 C CB  . LEU B 1 165 ? 19.40585  -41.46998 29.06040  1.000 43.36516  ? 125 LEU B CB  1 
ATOM   3289 C CG  . LEU B 1 165 ? 19.69385  -41.01805 27.62724  1.000 47.88173  ? 125 LEU B CG  1 
ATOM   3290 C CD1 . LEU B 1 165 ? 18.78515  -41.75185 26.65839  1.000 48.06578  ? 125 LEU B CD1 1 
ATOM   3291 C CD2 . LEU B 1 165 ? 19.51654  -39.51250 27.48322  1.000 48.00216  ? 125 LEU B CD2 1 
ATOM   3292 N N   . ALA B 1 166 ? 21.92921  -43.18961 29.58562  1.000 47.16613  ? 126 ALA B N   1 
ATOM   3293 C CA  . ALA B 1 166 ? 23.08887  -43.91409 29.06525  1.000 45.44287  ? 126 ALA B CA  1 
ATOM   3294 C C   . ALA B 1 166 ? 24.37133  -43.49782 29.77697  1.000 46.36315  ? 126 ALA B C   1 
ATOM   3295 O O   . ALA B 1 166 ? 25.44441  -43.44062 29.17161  1.000 40.32428  ? 126 ALA B O   1 
ATOM   3296 C CB  . ALA B 1 166 ? 23.22666  -43.73498 27.54965  1.000 42.27509  ? 126 ALA B CB  1 
ATOM   3297 N N   . ALA B 1 167 ? 24.26125  -43.20012 31.06828  1.000 46.70662  ? 127 ALA B N   1 
ATOM   3298 C CA  . ALA B 1 167 ? 25.36929  -42.64186 31.83572  1.000 45.04522  ? 127 ALA B CA  1 
ATOM   3299 C C   . ALA B 1 167 ? 25.97385  -43.71218 32.74271  1.000 56.92538  ? 127 ALA B C   1 
ATOM   3300 O O   . ALA B 1 167 ? 25.82030  -43.70361 33.96397  1.000 62.50897  ? 127 ALA B O   1 
ATOM   3301 C CB  . ALA B 1 167 ? 24.89822  -41.42934 32.63301  1.000 48.95714  ? 127 ALA B CB  1 
ATOM   3302 N N   . GLY B 1 168 ? 26.67554  -44.64625 32.11255  1.000 50.05781  ? 128 GLY B N   1 
ATOM   3303 C CA  . GLY B 1 168 ? 27.36896  -45.70598 32.82011  1.000 56.32047  ? 128 GLY B CA  1 
ATOM   3304 C C   . GLY B 1 168 ? 28.82367  -45.73476 32.39618  1.000 63.13701  ? 128 GLY B C   1 
ATOM   3305 O O   . GLY B 1 168 ? 29.45686  -44.70027 32.19189  1.000 56.53515  ? 128 GLY B O   1 
ATOM   3306 N N   . LEU B 1 169 ? 29.36134  -46.94576 32.26958  1.000 57.09595  ? 129 LEU B N   1 
ATOM   3307 C CA  . LEU B 1 169 ? 30.72452  -47.09724 31.77696  1.000 62.76138  ? 129 LEU B CA  1 
ATOM   3308 C C   . LEU B 1 169 ? 30.74632  -47.13916 30.25101  1.000 55.15046  ? 129 LEU B C   1 
ATOM   3309 O O   . LEU B 1 169 ? 31.48985  -46.38395 29.61722  1.000 56.84488  ? 129 LEU B O   1 
ATOM   3310 C CB  . LEU B 1 169 ? 31.38049  -48.33616 32.41178  1.000 63.94789  ? 129 LEU B CB  1 
ATOM   3311 C CG  . LEU B 1 169 ? 31.74448  -49.66952 31.74437  1.000 62.85187  ? 129 LEU B CG  1 
ATOM   3312 C CD1 . LEU B 1 169 ? 32.81252  -49.54665 30.66793  1.000 64.01610  ? 129 LEU B CD1 1 
ATOM   3313 C CD2 . LEU B 1 169 ? 32.19415  -50.65535 32.80701  1.000 63.85429  ? 129 LEU B CD2 1 
ATOM   3314 N N   . LEU B 1 170 ? 29.93451  -48.00595 29.65068  1.000 48.53225  ? 130 LEU B N   1 
ATOM   3315 C CA  . LEU B 1 170 ? 29.80613  -48.07841 28.19547  1.000 57.16150  ? 130 LEU B CA  1 
ATOM   3316 C C   . LEU B 1 170 ? 28.39834  -48.57194 27.89077  1.000 71.85600  ? 130 LEU B C   1 
ATOM   3317 O O   . LEU B 1 170 ? 28.10530  -49.77019 28.03210  1.000 71.11227  ? 130 LEU B O   1 
ATOM   3318 C CB  . LEU B 1 170 ? 30.85829  -48.99319 27.57494  1.000 60.78018  ? 130 LEU B CB  1 
ATOM   3319 C CG  . LEU B 1 170 ? 30.81631  -49.18366 26.05705  1.000 59.02955  ? 130 LEU B CG  1 
ATOM   3320 C CD1 . LEU B 1 170 ? 30.89821  -47.84470 25.33952  1.000 65.30105  ? 130 LEU B CD1 1 
ATOM   3321 C CD2 . LEU B 1 170 ? 31.93627  -50.11040 25.60635  1.000 52.48763  ? 130 LEU B CD2 1 
ATOM   3322 N N   . PRO B 1 171 ? 27.48838  -47.67662 27.46632  1.000 66.24443  ? 131 PRO B N   1 
ATOM   3323 C CA  . PRO B 1 171 ? 27.69318  -46.24714 27.17639  1.000 64.77855  ? 131 PRO B CA  1 
ATOM   3324 C C   . PRO B 1 171 ? 27.93857  -45.40491 28.42487  1.000 63.09338  ? 131 PRO B C   1 
ATOM   3325 O O   . PRO B 1 171 ? 27.64586  -45.82889 29.54174  1.000 53.27169  ? 131 PRO B O   1 
ATOM   3326 C CB  . PRO B 1 171 ? 26.38119  -45.85397 26.48521  1.000 56.39639  ? 131 PRO B CB  1 
ATOM   3327 C CG  . PRO B 1 171 ? 25.36199  -46.73493 27.13736  1.000 52.68424  ? 131 PRO B CG  1 
ATOM   3328 C CD  . PRO B 1 171 ? 26.06959  -48.05594 27.32878  1.000 65.07187  ? 131 PRO B CD  1 
ATOM   3329 N N   . GLY B 1 172 ? 28.47019  -44.19684 28.24721  1.000 51.15095  ? 132 GLY B N   1 
ATOM   3330 C CA  . GLY B 1 172 ? 28.83442  -43.35092 29.36567  1.000 43.32126  ? 132 GLY B CA  1 
ATOM   3331 C C   . GLY B 1 172 ? 30.20503  -42.71826 29.22471  1.000 50.71369  ? 132 GLY B C   1 
ATOM   3332 O O   . GLY B 1 172 ? 30.47792  -42.02192 28.24156  1.000 50.64819  ? 132 GLY B O   1 
ATOM   3333 N N   . THR B 1 173 ? 31.07871  -42.94814 30.20883  1.000 46.12284  ? 133 THR B N   1 
ATOM   3334 C CA  . THR B 1 173 ? 32.38902  -42.30382 30.19708  1.000 53.86815  ? 133 THR B CA  1 
ATOM   3335 C C   . THR B 1 173 ? 33.25176  -42.79029 29.03887  1.000 53.44546  ? 133 THR B C   1 
ATOM   3336 O O   . THR B 1 173 ? 34.04816  -42.01572 28.49620  1.000 52.56083  ? 133 THR B O   1 
ATOM   3337 C CB  . THR B 1 173 ? 33.10467  -42.54323 31.52561  1.000 49.10884  ? 133 THR B CB  1 
ATOM   3338 O OG1 . THR B 1 173 ? 33.09093  -43.94390 31.82910  1.000 51.61242  ? 133 THR B OG1 1 
ATOM   3339 C CG2 . THR B 1 173 ? 32.41377  -41.77632 32.64469  1.000 43.34681  ? 133 THR B CG2 1 
ATOM   3340 N N   . CYS B 1 174 ? 33.11070  -44.05954 28.64626  1.000 43.81824  ? 134 CYS B N   1 
ATOM   3341 C CA  . CYS B 1 174 ? 33.82917  -44.54866 27.47444  1.000 47.36323  ? 134 CYS B CA  1 
ATOM   3342 C C   . CYS B 1 174 ? 33.37675  -43.83123 26.21109  1.000 45.96663  ? 134 CYS B C   1 
ATOM   3343 O O   . CYS B 1 174 ? 34.18511  -43.59912 25.30562  1.000 42.29659  ? 134 CYS B O   1 
ATOM   3344 C CB  . CYS B 1 174 ? 33.64001  -46.05924 27.32755  1.000 42.59741  ? 134 CYS B CB  1 
ATOM   3345 S SG  . CYS B 1 174 ? 34.54864  -47.04253 28.54402  1.000 51.82183  ? 134 CYS B SG  1 
ATOM   3346 N N   . SER B 1 175 ? 32.09209  -43.48067 26.12720  1.000 48.87572  ? 135 SER B N   1 
ATOM   3347 C CA  . SER B 1 175 ? 31.62014  -42.68597 24.99934  1.000 51.14675  ? 135 SER B CA  1 
ATOM   3348 C C   . SER B 1 175 ? 32.29297  -41.31968 24.97378  1.000 48.38260  ? 135 SER B C   1 
ATOM   3349 O O   . SER B 1 175 ? 32.63177  -40.80610 23.90109  1.000 43.87238  ? 135 SER B O   1 
ATOM   3350 C CB  . SER B 1 175 ? 30.10013  -42.53474 25.05839  1.000 51.34960  ? 135 SER B CB  1 
ATOM   3351 O OG  . SER B 1 175 ? 29.46827  -43.77946 25.29039  1.000 66.90599  ? 135 SER B OG  1 
ATOM   3352 N N   . MET B 1 176 ? 32.47729  -40.70781 26.14652  1.000 41.49147  ? 136 MET B N   1 
ATOM   3353 C CA  . MET B 1 176 ? 33.12091  -39.39885 26.21353  1.000 49.98281  ? 136 MET B CA  1 
ATOM   3354 C C   . MET B 1 176 ? 34.57211  -39.47334 25.75305  1.000 52.80769  ? 136 MET B C   1 
ATOM   3355 O O   . MET B 1 176 ? 35.02307  -38.64849 24.94938  1.000 48.45018  ? 136 MET B O   1 
ATOM   3356 C CB  . MET B 1 176 ? 33.02680  -38.84448 27.63492  1.000 49.45810  ? 136 MET B CB  1 
ATOM   3357 C CG  . MET B 1 176 ? 31.62020  -38.87449 28.21024  1.000 45.81300  ? 136 MET B CG  1 
ATOM   3358 S SD  . MET B 1 176 ? 31.54368  -38.32506 29.92675  1.000 50.53924  ? 136 MET B SD  1 
ATOM   3359 C CE  . MET B 1 176 ? 32.20444  -36.66776 29.79644  1.000 46.01747  ? 136 MET B CE  1 
ATOM   3360 N N   . ILE B 1 177 ? 35.32322  -40.45169 26.26690  1.000 46.81384  ? 137 ILE B N   1 
ATOM   3361 C CA  . ILE B 1 177 ? 36.70294  -40.64889 25.82826  1.000 44.66196  ? 137 ILE B CA  1 
ATOM   3362 C C   . ILE B 1 177 ? 36.74490  -40.89727 24.32691  1.000 49.77082  ? 137 ILE B C   1 
ATOM   3363 O O   . ILE B 1 177 ? 37.53137  -40.28223 23.59762  1.000 48.96073  ? 137 ILE B O   1 
ATOM   3364 C CB  . ILE B 1 177 ? 37.35680  -41.80480 26.60773  1.000 53.48955  ? 137 ILE B CB  1 
ATOM   3365 C CG1 . ILE B 1 177 ? 37.22596  -41.58789 28.11927  1.000 50.16462  ? 137 ILE B CG1 1 
ATOM   3366 C CG2 . ILE B 1 177 ? 38.81258  -41.96741 26.19813  1.000 49.90616  ? 137 ILE B CG2 1 
ATOM   3367 C CD1 . ILE B 1 177 ? 37.96988  -40.38302 28.63867  1.000 61.02106  ? 137 ILE B CD1 1 
ATOM   3368 N N   . ARG B 1 178 ? 35.89189  -41.80576 23.84782  1.000 39.13434  ? 138 ARG B N   1 
ATOM   3369 C CA  . ARG B 1 178 ? 35.80314  -42.09311 22.41934  1.000 47.43591  ? 138 ARG B CA  1 
ATOM   3370 C C   . ARG B 1 178 ? 35.58171  -40.82420 21.60080  1.000 50.91520  ? 138 ARG B C   1 
ATOM   3371 O O   . ARG B 1 178 ? 36.21395  -40.62974 20.55511  1.000 46.04444  ? 138 ARG B O   1 
ATOM   3372 C CB  . ARG B 1 178 ? 34.67369  -43.09707 22.18105  1.000 54.33312  ? 138 ARG B CB  1 
ATOM   3373 C CG  . ARG B 1 178 ? 34.73447  -43.85951 20.87600  1.000 63.94661  ? 138 ARG B CG  1 
ATOM   3374 C CD  . ARG B 1 178 ? 34.10464  -45.23365 21.05594  1.000 83.81430  ? 138 ARG B CD  1 
ATOM   3375 N NE  . ARG B 1 178 ? 32.72738  -45.14736 21.53035  1.000 73.11521  ? 138 ARG B NE  1 
ATOM   3376 C CZ  . ARG B 1 178 ? 31.97440  -46.19391 21.84198  1.000 69.53804  ? 138 ARG B CZ  1 
ATOM   3377 N NH1 . ARG B 1 178 ? 32.44318  -47.42887 21.76873  1.000 64.84874  ? 138 ARG B NH1 1 
ATOM   3378 N NH2 . ARG B 1 178 ? 30.72368  -45.99573 22.24923  1.000 62.29961  ? 138 ARG B NH2 1 
ATOM   3379 N N   . SER B 1 179 ? 34.69175  -39.94403 22.06819  1.000 44.70759  ? 139 SER B N   1 
ATOM   3380 C CA  . SER B 1 179 ? 34.37703  -38.73204 21.31712  1.000 52.13141  ? 139 SER B CA  1 
ATOM   3381 C C   . SER B 1 179 ? 35.53549  -37.73847 21.33697  1.000 47.07389  ? 139 SER B C   1 
ATOM   3382 O O   . SER B 1 179 ? 35.76681  -37.02973 20.34995  1.000 43.93083  ? 139 SER B O   1 
ATOM   3383 C CB  . SER B 1 179 ? 33.10332  -38.09388 21.87245  1.000 49.08975  ? 139 SER B CB  1 
ATOM   3384 O OG  . SER B 1 179 ? 32.02902  -39.01851 21.87483  1.000 49.92618  ? 139 SER B OG  1 
ATOM   3385 N N   . ILE B 1 180 ? 36.27102  -37.66685 22.44944  1.000 43.79451  ? 140 ILE B N   1 
ATOM   3386 C CA  . ILE B 1 180 ? 37.41849  -36.76539 22.51982  1.000 43.73396  ? 140 ILE B CA  1 
ATOM   3387 C C   . ILE B 1 180 ? 38.50976  -37.21373 21.55642  1.000 46.82138  ? 140 ILE B C   1 
ATOM   3388 O O   . ILE B 1 180 ? 39.13570  -36.38984 20.87776  1.000 51.27762  ? 140 ILE B O   1 
ATOM   3389 C CB  . ILE B 1 180 ? 37.94283  -36.66580 23.96410  1.000 41.47724  ? 140 ILE B CB  1 
ATOM   3390 C CG1 . ILE B 1 180 ? 36.92468  -35.95991 24.85878  1.000 44.01613  ? 140 ILE B CG1 1 
ATOM   3391 C CG2 . ILE B 1 180 ? 39.25547  -35.92069 23.99942  1.000 40.61737  ? 140 ILE B CG2 1 
ATOM   3392 C CD1 . ILE B 1 180 ? 37.26698  -36.01240 26.33302  1.000 45.04205  ? 140 ILE B CD1 1 
ATOM   3393 N N   . LEU B 1 181 ? 38.75974  -38.52349 21.48662  1.000 52.32388  ? 141 LEU B N   1 
ATOM   3394 C CA  . LEU B 1 181 ? 39.68927  -39.05492 20.49513  1.000 53.68088  ? 141 LEU B CA  1 
ATOM   3395 C C   . LEU B 1 181 ? 39.25194  -38.69707 19.07927  1.000 53.28374  ? 141 LEU B C   1 
ATOM   3396 O O   . LEU B 1 181 ? 40.09153  -38.42646 18.21277  1.000 54.55273  ? 141 LEU B O   1 
ATOM   3397 C CB  . LEU B 1 181 ? 39.80961  -40.57304 20.64627  1.000 51.82135  ? 141 LEU B CB  1 
ATOM   3398 C CG  . LEU B 1 181 ? 40.19569  -41.15535 22.01002  1.000 46.42317  ? 141 LEU B CG  1 
ATOM   3399 C CD1 . LEU B 1 181 ? 40.33219  -42.66681 21.91745  1.000 48.99306  ? 141 LEU B CD1 1 
ATOM   3400 C CD2 . LEU B 1 181 ? 41.47812  -40.53958 22.53972  1.000 47.04612  ? 141 LEU B CD2 1 
ATOM   3401 N N   . GLU B 1 182 ? 37.94044  -38.70123 18.82380  1.000 45.84880  ? 142 GLU B N   1 
ATOM   3402 C CA  . GLU B 1 182 ? 37.44252  -38.48470 17.46768  1.000 44.73088  ? 142 GLU B CA  1 
ATOM   3403 C C   . GLU B 1 182 ? 37.86602  -37.12313 16.92340  1.000 57.39802  ? 142 GLU B C   1 
ATOM   3404 O O   . GLU B 1 182 ? 38.31624  -37.01875 15.77734  1.000 53.46851  ? 142 GLU B O   1 
ATOM   3405 C CB  . GLU B 1 182 ? 35.91907  -38.63431 17.43441  1.000 60.35003  ? 142 GLU B CB  1 
ATOM   3406 C CG  . GLU B 1 182 ? 35.31033  -38.62744 16.03290  1.000 59.64796  ? 142 GLU B CG  1 
ATOM   3407 C CD  . GLU B 1 182 ? 35.25813  -40.00811 15.39950  1.000 71.67422  ? 142 GLU B CD  1 
ATOM   3408 O OE1 . GLU B 1 182 ? 35.57626  -40.99859 16.09041  1.000 70.84568  ? 142 GLU B OE1 1 
ATOM   3409 O OE2 . GLU B 1 182 ? 34.89319  -40.09999 14.20971  1.000 76.15664  ? 142 GLU B OE2 1 
ATOM   3410 N N   . PHE B 1 183 ? 37.73096  -36.06178 17.72321  1.000 44.09121  ? 143 PHE B N   1 
ATOM   3411 C CA  . PHE B 1 183 ? 38.05125  -34.73844 17.19982  1.000 51.27546  ? 143 PHE B CA  1 
ATOM   3412 C C   . PHE B 1 183 ? 39.52710  -34.37284 17.32822  1.000 46.70741  ? 143 PHE B C   1 
ATOM   3413 O O   . PHE B 1 183 ? 39.96585  -33.42068 16.67317  1.000 54.21902  ? 143 PHE B O   1 
ATOM   3414 C CB  . PHE B 1 183 ? 37.15265  -33.65723 17.83668  1.000 50.14824  ? 143 PHE B CB  1 
ATOM   3415 C CG  . PHE B 1 183 ? 37.48045  -33.30612 19.26806  1.000 48.34426  ? 143 PHE B CG  1 
ATOM   3416 C CD1 . PHE B 1 183 ? 38.55999  -32.49098 19.57702  1.000 42.29883  ? 143 PHE B CD1 1 
ATOM   3417 C CD2 . PHE B 1 183 ? 36.65946  -33.73325 20.29894  1.000 49.38308  ? 143 PHE B CD2 1 
ATOM   3418 C CE1 . PHE B 1 183 ? 38.84428  -32.15236 20.88851  1.000 42.90664  ? 143 PHE B CE1 1 
ATOM   3419 C CE2 . PHE B 1 183 ? 36.93422  -33.39258 21.61287  1.000 50.21697  ? 143 PHE B CE2 1 
ATOM   3420 C CZ  . PHE B 1 183 ? 38.02989  -32.60229 21.90591  1.000 39.78282  ? 143 PHE B CZ  1 
ATOM   3421 N N   . MET B 1 184 ? 40.30656  -35.09068 18.14537  1.000 54.05668  ? 144 MET B N   1 
ATOM   3422 C CA  . MET B 1 184 ? 41.75355  -34.88841 18.10622  1.000 50.64221  ? 144 MET B CA  1 
ATOM   3423 C C   . MET B 1 184 ? 42.35932  -35.44240 16.82355  1.000 47.91230  ? 144 MET B C   1 
ATOM   3424 O O   . MET B 1 184 ? 43.38364  -34.93590 16.35395  1.000 52.26834  ? 144 MET B O   1 
ATOM   3425 C CB  . MET B 1 184 ? 42.43840  -35.52137 19.32028  1.000 45.94183  ? 144 MET B CB  1 
ATOM   3426 C CG  . MET B 1 184 ? 42.19302  -34.80658 20.63908  1.000 46.54797  ? 144 MET B CG  1 
ATOM   3427 S SD  . MET B 1 184 ? 43.15443  -35.51288 21.99731  1.000 50.48043  ? 144 MET B SD  1 
ATOM   3428 C CE  . MET B 1 184 ? 42.36443  -37.10197 22.18131  1.000 50.34721  ? 144 MET B CE  1 
ATOM   3429 N N   . ALA B 1 185 ? 41.73872  -36.46626 16.23894  1.000 48.98971  ? 145 ALA B N   1 
ATOM   3430 C CA  . ALA B 1 185 ? 42.22441  -37.06127 14.99504  1.000 54.87661  ? 145 ALA B CA  1 
ATOM   3431 C C   . ALA B 1 185 ? 41.01944  -37.50880 14.18490  1.000 54.22511  ? 145 ALA B C   1 
ATOM   3432 O O   . ALA B 1 185 ? 40.59871  -38.67046 14.25465  1.000 47.73127  ? 145 ALA B O   1 
ATOM   3433 C CB  . ALA B 1 185 ? 43.17712  -38.22725 15.25733  1.000 49.84872  ? 145 ALA B CB  1 
ATOM   3434 N N   . PRO B 1 186 ? 40.43006  -36.60042 13.39823  1.000 58.43003  ? 146 PRO B N   1 
ATOM   3435 C CA  . PRO B 1 186 ? 39.14944  -36.91040 12.73633  1.000 49.54573  ? 146 PRO B CA  1 
ATOM   3436 C C   . PRO B 1 186 ? 39.21588  -38.05533 11.74175  1.000 54.20573  ? 146 PRO B C   1 
ATOM   3437 O O   . PRO B 1 186 ? 38.23108  -38.79144 11.60364  1.000 58.74554  ? 146 PRO B O   1 
ATOM   3438 C CB  . PRO B 1 186 ? 38.78797  -35.58771 12.04569  1.000 48.95381  ? 146 PRO B CB  1 
ATOM   3439 C CG  . PRO B 1 186 ? 39.50547  -34.54050 12.83230  1.000 55.22876  ? 146 PRO B CG  1 
ATOM   3440 C CD  . PRO B 1 186 ? 40.79085  -35.17899 13.26832  1.000 58.73986  ? 146 PRO B CD  1 
ATOM   3441 N N   . TYR B 1 187 ? 40.33557  -38.23943 11.04907  1.000 47.90795  ? 147 TYR B N   1 
ATOM   3442 C CA  . TYR B 1 187 ? 40.48680  -39.32952 10.09321  1.000 53.73201  ? 147 TYR B CA  1 
ATOM   3443 C C   . TYR B 1 187 ? 41.18442  -40.49641 10.77501  1.000 56.83500  ? 147 TYR B C   1 
ATOM   3444 O O   . TYR B 1 187 ? 42.21184  -40.30815 11.43040  1.000 57.82203  ? 147 TYR B O   1 
ATOM   3445 C CB  . TYR B 1 187 ? 41.29149  -38.89171 8.86767   1.000 45.23544  ? 147 TYR B CB  1 
ATOM   3446 C CG  . TYR B 1 187 ? 40.71126  -37.71843 8.11058   1.000 61.79791  ? 147 TYR B CG  1 
ATOM   3447 C CD1 . TYR B 1 187 ? 39.34130  -37.49270 8.07917   1.000 57.34405  ? 147 TYR B CD1 1 
ATOM   3448 C CD2 . TYR B 1 187 ? 41.53633  -36.83858 7.42044   1.000 66.32405  ? 147 TYR B CD2 1 
ATOM   3449 C CE1 . TYR B 1 187 ? 38.81042  -36.42443 7.38689   1.000 65.88120  ? 147 TYR B CE1 1 
ATOM   3450 C CE2 . TYR B 1 187 ? 41.01369  -35.76560 6.72581   1.000 63.61192  ? 147 TYR B CE2 1 
ATOM   3451 C CZ  . TYR B 1 187 ? 39.65012  -35.56414 6.71225   1.000 60.31593  ? 147 TYR B CZ  1 
ATOM   3452 O OH  . TYR B 1 187 ? 39.12403  -34.49780 6.02086   1.000 70.51323  ? 147 TYR B OH  1 
ATOM   3453 N N   . GLY B 1 188 ? 40.63678  -41.69106 10.61194  1.000 48.83384  ? 148 GLY B N   1 
ATOM   3454 C CA  . GLY B 1 188 ? 41.20343  -42.88078 11.20155  1.000 48.38075  ? 148 GLY B CA  1 
ATOM   3455 C C   . GLY B 1 188 ? 40.11994  -43.76783 11.77038  1.000 56.17371  ? 148 GLY B C   1 
ATOM   3456 O O   . GLY B 1 188 ? 38.93619  -43.60233 11.48275  1.000 55.49590  ? 148 GLY B O   1 
ATOM   3457 N N   . ILE B 1 189 ? 40.54039  -44.72526 12.59546  1.000 42.52316  ? 149 ILE B N   1 
ATOM   3458 C CA  . ILE B 1 189 ? 39.66133  -45.75693 13.13153  1.000 45.32038  ? 149 ILE B CA  1 
ATOM   3459 C C   . ILE B 1 189 ? 39.90725  -45.88913 14.62893  1.000 50.35310  ? 149 ILE B C   1 
ATOM   3460 O O   . ILE B 1 189 ? 41.05501  -45.84226 15.08565  1.000 46.45882  ? 149 ILE B O   1 
ATOM   3461 C CB  . ILE B 1 189 ? 39.88748  -47.11037 12.42216  1.000 49.04286  ? 149 ILE B CB  1 
ATOM   3462 C CG1 . ILE B 1 189 ? 39.55066  -47.00583 10.93404  1.000 51.92487  ? 149 ILE B CG1 1 
ATOM   3463 C CG2 . ILE B 1 189 ? 39.07627  -48.20960 13.08102  1.000 50.85360  ? 149 ILE B CG2 1 
ATOM   3464 C CD1 . ILE B 1 189 ? 39.75981  -48.29171 10.17650  1.000 57.08583  ? 149 ILE B CD1 1 
ATOM   3465 N N   . THR B 1 190 ? 38.82816  -46.05494 15.39165  1.000 48.26376  ? 150 THR B N   1 
ATOM   3466 C CA  . THR B 1 190 ? 38.89632  -46.33118 16.82074  1.000 49.59213  ? 150 THR B CA  1 
ATOM   3467 C C   . THR B 1 190 ? 38.39371  -47.74313 17.08872  1.000 47.13577  ? 150 THR B C   1 
ATOM   3468 O O   . THR B 1 190 ? 37.34422  -48.14069 16.57217  1.000 53.05534  ? 150 THR B O   1 
ATOM   3469 C CB  . THR B 1 190 ? 38.06764  -45.32171 17.62091  1.000 42.49741  ? 150 THR B CB  1 
ATOM   3470 O OG1 . THR B 1 190 ? 38.60889  -44.00742 17.45243  1.000 49.35591  ? 150 THR B OG1 1 
ATOM   3471 C CG2 . THR B 1 190 ? 38.07837  -45.67602 19.09961  1.000 44.96744  ? 150 THR B CG2 1 
ATOM   3472 N N   . TYR B 1 191 ? 39.14461  -48.49551 17.88637  1.000 46.84654  ? 151 TYR B N   1 
ATOM   3473 C CA  . TYR B 1 191 ? 38.75675  -49.83310 18.30850  1.000 47.69632  ? 151 TYR B CA  1 
ATOM   3474 C C   . TYR B 1 191 ? 38.41136  -49.80672 19.78842  1.000 44.78272  ? 151 TYR B C   1 
ATOM   3475 O O   . TYR B 1 191 ? 39.20642  -49.33129 20.60473  1.000 57.37770  ? 151 TYR B O   1 
ATOM   3476 C CB  . TYR B 1 191 ? 39.88054  -50.83776 18.05360  1.000 49.84623  ? 151 TYR B CB  1 
ATOM   3477 C CG  . TYR B 1 191 ? 40.22186  -51.01880 16.59545  1.000 55.35625  ? 151 TYR B CG  1 
ATOM   3478 C CD1 . TYR B 1 191 ? 39.23636  -51.29965 15.66115  1.000 50.83870  ? 151 TYR B CD1 1 
ATOM   3479 C CD2 . TYR B 1 191 ? 41.53213  -50.90247 16.15047  1.000 44.99757  ? 151 TYR B CD2 1 
ATOM   3480 C CE1 . TYR B 1 191 ? 39.54735  -51.46815 14.32115  1.000 61.97568  ? 151 TYR B CE1 1 
ATOM   3481 C CE2 . TYR B 1 191 ? 41.85234  -51.06651 14.81395  1.000 42.25005  ? 151 TYR B CE2 1 
ATOM   3482 C CZ  . TYR B 1 191 ? 40.85587  -51.34847 13.90349  1.000 68.50638  ? 151 TYR B CZ  1 
ATOM   3483 O OH  . TYR B 1 191 ? 41.17010  -51.51203 12.57288  1.000 62.69904  ? 151 TYR B OH  1 
ATOM   3484 N N   . THR B 1 192 ? 37.23408  -50.31232 20.13253  1.000 50.49994  ? 152 THR B N   1 
ATOM   3485 C CA  . THR B 1 192 ? 36.82246  -50.44472 21.52373  1.000 52.01020  ? 152 THR B CA  1 
ATOM   3486 C C   . THR B 1 192 ? 36.82376  -51.92761 21.86445  1.000 51.46711  ? 152 THR B C   1 
ATOM   3487 O O   . THR B 1 192 ? 35.99311  -52.68717 21.35557  1.000 55.23858  ? 152 THR B O   1 
ATOM   3488 C CB  . THR B 1 192 ? 35.44486  -49.83242 21.75535  1.000 55.43710  ? 152 THR B CB  1 
ATOM   3489 O OG1 . THR B 1 192 ? 35.45162  -48.45860 21.34237  1.000 60.04303  ? 152 THR B OG1 1 
ATOM   3490 C CG2 . THR B 1 192 ? 35.07509  -49.91742 23.23189  1.000 42.87008  ? 152 THR B CG2 1 
ATOM   3491 N N   . ASN B 1 193 ? 37.74496  -52.33250 22.73126  1.000 44.11707  ? 153 ASN B N   1 
ATOM   3492 C CA  . ASN B 1 193 ? 37.95641  -53.73512 23.06467  1.000 42.32637  ? 153 ASN B CA  1 
ATOM   3493 C C   . ASN B 1 193 ? 37.52109  -53.93599 24.51104  1.000 56.48426  ? 153 ASN B C   1 
ATOM   3494 O O   . ASN B 1 193 ? 38.20600  -53.48970 25.43784  1.000 59.42526  ? 153 ASN B O   1 
ATOM   3495 C CB  . ASN B 1 193 ? 39.42052  -54.12393 22.86216  1.000 38.54796  ? 153 ASN B CB  1 
ATOM   3496 C CG  . ASN B 1 193 ? 39.93578  -53.76381 21.47588  1.000 51.74080  ? 153 ASN B CG  1 
ATOM   3497 O OD1 . ASN B 1 193 ? 39.57610  -54.39510 20.48235  1.000 56.40757  ? 153 ASN B OD1 1 
ATOM   3498 N ND2 . ASN B 1 193 ? 40.78347  -52.74036 21.40615  1.000 51.40035  ? 153 ASN B ND2 1 
ATOM   3499 N N   . VAL B 1 194 ? 36.38765  -54.60841 24.70098  1.000 53.94750  ? 154 VAL B N   1 
ATOM   3500 C CA  . VAL B 1 194 ? 35.80744  -54.81332 26.02379  1.000 48.44998  ? 154 VAL B CA  1 
ATOM   3501 C C   . VAL B 1 194 ? 36.41848  -56.08983 26.59010  1.000 53.24770  ? 154 VAL B C   1 
ATOM   3502 O O   . VAL B 1 194 ? 36.02437  -57.19772 26.22000  1.000 46.89549  ? 154 VAL B O   1 
ATOM   3503 C CB  . VAL B 1 194 ? 34.28248  -54.89585 25.97014  1.000 43.68113  ? 154 VAL B CB  1 
ATOM   3504 C CG1 . VAL B 1 194 ? 33.71740  -55.06702 27.37103  1.000 39.99645  ? 154 VAL B CG1 1 
ATOM   3505 C CG2 . VAL B 1 194 ? 33.70760  -53.66312 25.29523  1.000 44.70347  ? 154 VAL B CG2 1 
ATOM   3506 N N   . GLY B 1 195 ? 37.38215  -55.92700 27.49887  1.000 79.73094  ? 155 GLY B N   1 
ATOM   3507 C CA  . GLY B 1 195 ? 38.15414  -57.02489 28.03727  1.000 56.93098  ? 155 GLY B CA  1 
ATOM   3508 C C   . GLY B 1 195 ? 37.31026  -58.07573 28.72687  1.000 71.78298  ? 155 GLY B C   1 
ATOM   3509 O O   . GLY B 1 195 ? 36.10234  -57.90012 28.92406  1.000 78.45939  ? 155 GLY B O   1 
ATOM   3510 N N   . PRO B 1 196 ? 37.94329  -59.20343 29.11032  1.000 69.00496  ? 156 PRO B N   1 
ATOM   3511 C CA  . PRO B 1 196 ? 37.19189  -60.31807 29.70786  1.000 63.58259  ? 156 PRO B CA  1 
ATOM   3512 C C   . PRO B 1 196 ? 36.33277  -59.88160 30.88183  1.000 61.25130  ? 156 PRO B C   1 
ATOM   3513 O O   . PRO B 1 196 ? 36.83536  -59.36769 31.88600  1.000 66.41702  ? 156 PRO B O   1 
ATOM   3514 C CB  . PRO B 1 196 ? 38.29493  -61.28710 30.14989  1.000 58.85462  ? 156 PRO B CB  1 
ATOM   3515 C CG  . PRO B 1 196 ? 39.44105  -60.97611 29.25251  1.000 61.31961  ? 156 PRO B CG  1 
ATOM   3516 C CD  . PRO B 1 196 ? 39.38199  -59.49823 29.00868  1.000 63.43157  ? 156 PRO B CD  1 
ATOM   3517 N N   . GLY B 1 197 ? 35.02770  -60.08103 30.74668  1.000 56.71356  ? 157 GLY B N   1 
ATOM   3518 C CA  . GLY B 1 197 ? 34.07117  -59.66213 31.75448  1.000 62.82170  ? 157 GLY B CA  1 
ATOM   3519 C C   . GLY B 1 197 ? 32.71851  -60.25848 31.44762  1.000 64.99733  ? 157 GLY B C   1 
ATOM   3520 O O   . GLY B 1 197 ? 32.48356  -60.79548 30.36131  1.000 59.62984  ? 157 GLY B O   1 
ATOM   3521 N N   . MET B 1 198 ? 31.82606  -60.15689 32.42685  1.000 60.04931  ? 158 MET B N   1 
ATOM   3522 C CA  . MET B 1 198 ? 30.49942  -60.73110 32.27244  1.000 62.76524  ? 158 MET B CA  1 
ATOM   3523 C C   . MET B 1 198 ? 29.65315  -59.87631 31.34246  1.000 62.57475  ? 158 MET B C   1 
ATOM   3524 O O   . MET B 1 198 ? 29.76442  -58.64743 31.32598  1.000 66.22113  ? 158 MET B O   1 
ATOM   3525 C CB  . MET B 1 198 ? 29.78313  -60.82756 33.61864  1.000 52.77518  ? 158 MET B CB  1 
ATOM   3526 C CG  . MET B 1 198 ? 30.34807  -61.80239 34.62131  1.000 83.19840  ? 158 MET B CG  1 
ATOM   3527 S SD  . MET B 1 198 ? 29.28926  -61.78163 36.08188  1.000 93.56344  ? 158 MET B SD  1 
ATOM   3528 C CE  . MET B 1 198 ? 27.67830  -61.90379 35.31020  1.000 58.39714  ? 158 MET B CE  1 
ATOM   3529 N N   . SER B 1 199 ? 28.80666  -60.53625 30.56086  1.000 62.65727  ? 159 SER B N   1 
ATOM   3530 C CA  . SER B 1 199 ? 27.75237  -59.86636 29.80963  1.000 77.04860  ? 159 SER B CA  1 
ATOM   3531 C C   . SER B 1 199 ? 26.47429  -60.35922 30.47326  1.000 85.85234  ? 159 SER B C   1 
ATOM   3532 O O   . SER B 1 199 ? 26.07194  -61.51200 30.28953  1.000 89.41028  ? 159 SER B O   1 
ATOM   3533 C CB  . SER B 1 199 ? 27.80338  -60.21317 28.32551  1.000 73.05081  ? 159 SER B CB  1 
ATOM   3534 O OG  . SER B 1 199 ? 26.70351  -59.65884 27.62270  1.000 96.74340  ? 159 SER B OG  1 
ATOM   3535 N N   . MET B 1 200 ? 25.82984  -59.47874 31.23877  1.000 85.37566  ? 160 MET B N   1 
ATOM   3536 C CA  . MET B 1 200 ? 24.67124  -59.90101 32.01099  1.000 88.44878  ? 160 MET B CA  1 
ATOM   3537 C C   . MET B 1 200 ? 23.39817  -59.97542 31.18341  1.000 93.33768  ? 160 MET B C   1 
ATOM   3538 O O   . MET B 1 200 ? 22.41640  -60.56646 31.64255  1.000 93.65581  ? 160 MET B O   1 
ATOM   3539 C CB  . MET B 1 200 ? 24.46233  -58.94620 33.19009  1.000 89.85008  ? 160 MET B CB  1 
ATOM   3540 C CG  . MET B 1 200 ? 24.92314  -59.46917 34.54184  1.000 100.94643 ? 160 MET B CG  1 
ATOM   3541 S SD  . MET B 1 200 ? 23.85459  -60.77283 35.17687  1.000 126.63909 ? 160 MET B SD  1 
ATOM   3542 C CE  . MET B 1 200 ? 24.35938  -60.82843 36.89587  1.000 79.99611  ? 160 MET B CE  1 
ATOM   3543 N N   . SER B 1 201 ? 23.38734  -59.40674 29.97598  1.000 92.70687  ? 161 SER B N   1 
ATOM   3544 C CA  . SER B 1 201 ? 22.24927  -59.61697 29.09036  1.000 90.92000  ? 161 SER B CA  1 
ATOM   3545 C C   . SER B 1 201 ? 22.37768  -60.91160 28.30146  1.000 88.37551  ? 161 SER B C   1 
ATOM   3546 O O   . SER B 1 201 ? 21.36433  -61.51430 27.92922  1.000 91.04455  ? 161 SER B O   1 
ATOM   3547 C CB  . SER B 1 201 ? 22.10137  -58.42854 28.13764  1.000 76.91310  ? 161 SER B CB  1 
ATOM   3548 O OG  . SER B 1 201 ? 23.27275  -58.25348 27.35863  1.000 90.58267  ? 161 SER B OG  1 
ATOM   3549 N N   . ALA B 1 202 ? 23.60737  -61.35665 28.04749  1.000 85.43405  ? 162 ALA B N   1 
ATOM   3550 C CA  . ALA B 1 202 ? 23.81306  -62.64264 27.39867  1.000 94.63551  ? 162 ALA B CA  1 
ATOM   3551 C C   . ALA B 1 202 ? 23.76007  -63.78969 28.39463  1.000 94.22192  ? 162 ALA B C   1 
ATOM   3552 O O   . ALA B 1 202 ? 23.38541  -64.90855 28.02583  1.000 94.50342  ? 162 ALA B O   1 
ATOM   3553 C CB  . ALA B 1 202 ? 25.14917  -62.64676 26.65668  1.000 85.06697  ? 162 ALA B CB  1 
ATOM   3554 N N   . SER B 1 203 ? 24.13143  -63.52940 29.65164  1.000 86.03027  ? 163 SER B N   1 
ATOM   3555 C CA  . SER B 1 203 ? 24.06870  -64.56652 30.67488  1.000 90.65468  ? 163 SER B CA  1 
ATOM   3556 C C   . SER B 1 203 ? 22.62938  -64.94893 30.99271  1.000 104.57854 ? 163 SER B C   1 
ATOM   3557 O O   . SER B 1 203 ? 22.31829  -66.13518 31.15616  1.000 107.54262 ? 163 SER B O   1 
ATOM   3558 C CB  . SER B 1 203 ? 24.79246  -64.09968 31.93618  1.000 85.98493  ? 163 SER B CB  1 
ATOM   3559 O OG  . SER B 1 203 ? 26.18282  -63.96212 31.70234  1.000 88.25087  ? 163 SER B OG  1 
ATOM   3560 N N   . VAL B 1 204 ? 21.73506  -63.96133 31.08564  1.000 103.09110 ? 164 VAL B N   1 
ATOM   3561 C CA  . VAL B 1 204 ? 20.34243  -64.26808 31.38775  1.000 104.05513 ? 164 VAL B CA  1 
ATOM   3562 C C   . VAL B 1 204 ? 19.61609  -64.84333 30.18078  1.000 97.76812  ? 164 VAL B C   1 
ATOM   3563 O O   . VAL B 1 204 ? 18.59492  -65.52219 30.34550  1.000 104.15742 ? 164 VAL B O   1 
ATOM   3564 C CB  . VAL B 1 204 ? 19.60458  -63.02201 31.91381  1.000 91.52460  ? 164 VAL B CB  1 
ATOM   3565 C CG1 . VAL B 1 204 ? 20.32199  -62.45181 33.12805  1.000 91.55159  ? 164 VAL B CG1 1 
ATOM   3566 C CG2 . VAL B 1 204 ? 19.48019  -61.97588 30.81634  1.000 86.61268  ? 164 VAL B CG2 1 
ATOM   3567 N N   . ALA B 1 205 ? 20.11129  -64.58959 28.96617  1.000 93.42158  ? 165 ALA B N   1 
ATOM   3568 C CA  . ALA B 1 205 ? 19.48585  -65.17993 27.78926  1.000 91.57241  ? 165 ALA B CA  1 
ATOM   3569 C C   . ALA B 1 205 ? 19.75403  -66.67801 27.71559  1.000 103.47936 ? 165 ALA B C   1 
ATOM   3570 O O   . ALA B 1 205 ? 18.86970  -67.45258 27.33372  1.000 106.09205 ? 165 ALA B O   1 
ATOM   3571 C CB  . ALA B 1 205 ? 19.98249  -64.47880 26.52591  1.000 85.47533  ? 165 ALA B CB  1 
ATOM   3572 N N   . VAL B 1 206 ? 20.96027  -67.10881 28.09728  1.000 105.78483 ? 166 VAL B N   1 
ATOM   3573 C CA  . VAL B 1 206 ? 21.25865  -68.53544 28.14862  1.000 102.31653 ? 166 VAL B CA  1 
ATOM   3574 C C   . VAL B 1 206 ? 20.54949  -69.20237 29.32104  1.000 108.64434 ? 166 VAL B C   1 
ATOM   3575 O O   . VAL B 1 206 ? 20.36780  -70.42588 29.32088  1.000 108.38127 ? 166 VAL B O   1 
ATOM   3576 C CB  . VAL B 1 206 ? 22.78256  -68.76022 28.20160  1.000 101.37196 ? 166 VAL B CB  1 
ATOM   3577 C CG1 . VAL B 1 206 ? 23.12179  -70.23902 28.05116  1.000 108.87688 ? 166 VAL B CG1 1 
ATOM   3578 C CG2 . VAL B 1 206 ? 23.46889  -67.95878 27.11127  1.000 95.60775  ? 166 VAL B CG2 1 
ATOM   3579 N N   . LYS B 1 207 ? 20.11504  -68.41909 30.31182  1.000 102.50244 ? 167 LYS B N   1 
ATOM   3580 C CA  . LYS B 1 207 ? 19.45557  -68.98982 31.48175  1.000 106.72792 ? 167 LYS B CA  1 
ATOM   3581 C C   . LYS B 1 207 ? 18.15564  -69.67973 31.08696  1.000 119.65154 ? 167 LYS B C   1 
ATOM   3582 O O   . LYS B 1 207 ? 17.90267  -70.82510 31.47870  1.000 122.77197 ? 167 LYS B O   1 
ATOM   3583 C CB  . LYS B 1 207 ? 19.18384  -67.89418 32.51550  1.000 99.03031  ? 167 LYS B CB  1 
ATOM   3584 C CG  . LYS B 1 207 ? 19.84675  -68.09599 33.87023  1.000 108.37684 ? 167 LYS B CG  1 
ATOM   3585 C CD  . LYS B 1 207 ? 21.09778  -67.23653 34.01977  1.000 110.00981 ? 167 LYS B CD  1 
ATOM   3586 C CE  . LYS B 1 207 ? 21.21251  -66.65459 35.42581  1.000 95.98869  ? 167 LYS B CE  1 
ATOM   3587 N NZ  . LYS B 1 207 ? 22.45344  -65.84456 35.59652  1.000 96.40004  ? 167 LYS B NZ  1 
ATOM   3588 N N   . ALA B 1 208 ? 17.31468  -68.98989 30.31286  1.000 114.05527 ? 168 ALA B N   1 
ATOM   3589 C CA  . ALA B 1 208 ? 16.02138  -69.50520 29.87732  1.000 110.48973 ? 168 ALA B CA  1 
ATOM   3590 C C   . ALA B 1 208 ? 16.12093  -70.53159 28.75249  1.000 113.44956 ? 168 ALA B C   1 
ATOM   3591 O O   . ALA B 1 208 ? 15.08201  -71.01682 28.28862  1.000 116.95491 ? 168 ALA B O   1 
ATOM   3592 C CB  . ALA B 1 208 ? 15.12467  -68.34391 29.43611  1.000 108.32648 ? 168 ALA B CB  1 
ATOM   3593 N N   . ILE B 1 209 ? 17.32703  -70.87619 28.30840  1.000 108.32419 ? 169 ILE B N   1 
ATOM   3594 C CA  . ILE B 1 209 ? 17.49812  -71.78719 27.18149  1.000 113.82150 ? 169 ILE B CA  1 
ATOM   3595 C C   . ILE B 1 209 ? 17.28803  -73.22353 27.64841  1.000 124.04767 ? 169 ILE B C   1 
ATOM   3596 O O   . ILE B 1 209 ? 17.70218  -73.61378 28.74242  1.000 126.07769 ? 169 ILE B O   1 
ATOM   3597 C CB  . ILE B 1 209 ? 18.87744  -71.59950 26.51793  1.000 118.25530 ? 169 ILE B CB  1 
ATOM   3598 C CG1 . ILE B 1 209 ? 18.97095  -70.21599 25.88763  1.000 115.69515 ? 169 ILE B CG1 1 
ATOM   3599 C CG2 . ILE B 1 209 ? 19.11050  -72.67024 25.46397  1.000 117.92922 ? 169 ILE B CG2 1 
ATOM   3600 C CD1 . ILE B 1 209 ? 20.18136  -70.03181 24.98425  1.000 117.70282 ? 169 ILE B CD1 1 
ATOM   3601 N N   . GLU B 1 210 ? 16.57655  -74.00018 26.83248  1.000 130.67927 ? 170 GLU B N   1 
ATOM   3602 C CA  . GLU B 1 210 ? 16.26919  -75.39436 27.14110  1.000 128.95044 ? 170 GLU B CA  1 
ATOM   3603 C C   . GLU B 1 210 ? 17.54663  -76.15741 27.47708  1.000 130.46916 ? 170 GLU B C   1 
ATOM   3604 O O   . GLU B 1 210 ? 18.45084  -76.27615 26.64006  1.000 127.71072 ? 170 GLU B O   1 
ATOM   3605 C CB  . GLU B 1 210 ? 15.54593  -76.05485 25.95786  1.000 121.88699 ? 170 GLU B CB  1 
ATOM   3606 C CG  . GLU B 1 210 ? 14.93471  -77.44220 26.25554  1.000 126.00318 ? 170 GLU B CG  1 
ATOM   3607 C CD  . GLU B 1 210 ? 15.93246  -78.60569 26.19477  1.000 137.55237 ? 170 GLU B CD  1 
ATOM   3608 O OE1 . GLU B 1 210 ? 17.03112  -78.46735 25.61115  1.000 134.35819 ? 170 GLU B OE1 1 
ATOM   3609 O OE2 . GLU B 1 210 ? 15.59616  -79.69082 26.71357  1.000 131.19677 ? 170 GLU B OE2 1 
ATOM   3610 N N   . GLY B 1 211 ? 17.61586  -76.68736 28.69642  1.000 121.40397 ? 171 GLY B N   1 
ATOM   3611 C CA  . GLY B 1 211 ? 18.68993  -77.58357 29.07222  1.000 112.62561 ? 171 GLY B CA  1 
ATOM   3612 C C   . GLY B 1 211 ? 19.72837  -77.04688 30.03939  1.000 115.59573 ? 171 GLY B C   1 
ATOM   3613 O O   . GLY B 1 211 ? 20.52558  -77.84266 30.55546  1.000 108.59696 ? 171 GLY B O   1 
ATOM   3614 N N   . VAL B 1 212 ? 19.73950  -75.75045 30.33135  1.000 115.12154 ? 172 VAL B N   1 
ATOM   3615 C CA  . VAL B 1 212 ? 20.73792  -75.14204 31.20828  1.000 113.29299 ? 172 VAL B CA  1 
ATOM   3616 C C   . VAL B 1 212 ? 20.08859  -74.72511 32.52894  1.000 108.25869 ? 172 VAL B C   1 
ATOM   3617 O O   . VAL B 1 212 ? 19.06303  -74.03017 32.54477  1.000 102.53501 ? 172 VAL B O   1 
ATOM   3618 C CB  . VAL B 1 212 ? 21.44405  -73.96465 30.51062  1.000 108.62508 ? 172 VAL B CB  1 
ATOM   3619 C CG1 . VAL B 1 212 ? 20.79079  -73.67476 29.17166  1.000 106.66325 ? 172 VAL B CG1 1 
ATOM   3620 C CG2 . VAL B 1 212 ? 21.47945  -72.71367 31.39523  1.000 113.25690 ? 172 VAL B CG2 1 
ATOM   3621 N N   . LYS B 1 213 ? 20.64035  -75.24042 33.63331  1.000 96.93022  ? 173 LYS B N   1 
ATOM   3622 C CA  . LYS B 1 213 ? 20.21036  -74.86976 34.97982  1.000 100.06836 ? 173 LYS B CA  1 
ATOM   3623 C C   . LYS B 1 213 ? 20.70434  -73.47442 35.35365  1.000 104.06435 ? 173 LYS B C   1 
ATOM   3624 O O   . LYS B 1 213 ? 19.94045  -72.65507 35.87734  1.000 94.75032  ? 173 LYS B O   1 
ATOM   3625 C CB  . LYS B 1 213 ? 20.72482  -75.91303 35.97844  1.000 95.78648  ? 173 LYS B CB  1 
ATOM   3626 C CG  . LYS B 1 213 ? 20.40651  -75.65556 37.43820  1.000 97.71145  ? 173 LYS B CG  1 
ATOM   3627 C CD  . LYS B 1 213 ? 21.16055  -76.65100 38.31854  1.000 101.90509 ? 173 LYS B CD  1 
ATOM   3628 C CE  . LYS B 1 213 ? 20.85657  -76.46313 39.79886  1.000 102.55619 ? 173 LYS B CE  1 
ATOM   3629 N NZ  . LYS B 1 213 ? 21.75653  -77.29607 40.65027  1.000 105.45002 ? 173 LYS B NZ  1 
ATOM   3630 N N   . ASP B 1 214 ? 21.97974  -73.18986 35.09109  1.000 99.89289  ? 174 ASP B N   1 
ATOM   3631 C CA  . ASP B 1 214 ? 22.52997  -71.84777 35.22122  1.000 97.09583  ? 174 ASP B CA  1 
ATOM   3632 C C   . ASP B 1 214 ? 23.57542  -71.63345 34.13459  1.000 92.06423  ? 174 ASP B C   1 
ATOM   3633 O O   . ASP B 1 214 ? 24.07922  -72.58691 33.53440  1.000 83.33835  ? 174 ASP B O   1 
ATOM   3634 C CB  . ASP B 1 214 ? 23.14164  -71.61014 36.60874  1.000 91.37962  ? 174 ASP B CB  1 
ATOM   3635 C CG  . ASP B 1 214 ? 23.19131  -70.13513 36.97901  1.000 95.63920  ? 174 ASP B CG  1 
ATOM   3636 O OD1 . ASP B 1 214 ? 22.91376  -69.28888 36.10214  1.000 80.28370  ? 174 ASP B OD1 1 
ATOM   3637 O OD2 . ASP B 1 214 ? 23.50729  -69.81917 38.14622  1.000 95.41085  ? 174 ASP B OD2 1 
ATOM   3638 N N   . ALA B 1 215 ? 23.90752  -70.36573 33.88830  1.000 86.85592  ? 175 ALA B N   1 
ATOM   3639 C CA  . ALA B 1 215 ? 24.85906  -70.04352 32.83426  1.000 89.96725  ? 175 ALA B CA  1 
ATOM   3640 C C   . ALA B 1 215 ? 25.58264  -68.73562 33.12911  1.000 81.98811  ? 175 ALA B C   1 
ATOM   3641 O O   . ALA B 1 215 ? 25.02951  -67.82106 33.74705  1.000 81.10647  ? 175 ALA B O   1 
ATOM   3642 C CB  . ALA B 1 215 ? 24.16791  -69.95683 31.46986  1.000 86.93434  ? 175 ALA B CB  1 
ATOM   3643 N N   . LEU B 1 216 ? 26.83636  -68.66817 32.68085  1.000 79.22245  ? 176 LEU B N   1 
ATOM   3644 C CA  . LEU B 1 216 ? 27.63737  -67.45024 32.69843  1.000 71.99555  ? 176 LEU B CA  1 
ATOM   3645 C C   . LEU B 1 216 ? 28.17094  -67.18266 31.29991  1.000 65.87085  ? 176 LEU B C   1 
ATOM   3646 O O   . LEU B 1 216 ? 28.82254  -68.04815 30.70715  1.000 59.92562  ? 176 LEU B O   1 
ATOM   3647 C CB  . LEU B 1 216 ? 28.80034  -67.54495 33.69041  1.000 64.55030  ? 176 LEU B CB  1 
ATOM   3648 C CG  . LEU B 1 216 ? 29.77268  -66.36604 33.58412  1.000 69.89636  ? 176 LEU B CG  1 
ATOM   3649 C CD1 . LEU B 1 216 ? 29.05814  -65.05188 33.86134  1.000 65.57462  ? 176 LEU B CD1 1 
ATOM   3650 C CD2 . LEU B 1 216 ? 30.96412  -66.54816 34.51414  1.000 62.16661  ? 176 LEU B CD2 1 
ATOM   3651 N N   . ALA B 1 217 ? 27.89506  -65.99116 30.77690  1.000 61.61794  ? 177 ALA B N   1 
ATOM   3652 C CA  . ALA B 1 217 ? 28.35313  -65.58432 29.45512  1.000 67.82356  ? 177 ALA B CA  1 
ATOM   3653 C C   . ALA B 1 217 ? 29.39143  -64.47721 29.58887  1.000 72.74309  ? 177 ALA B C   1 
ATOM   3654 O O   . ALA B 1 217 ? 29.15950  -63.48170 30.28398  1.000 66.69686  ? 177 ALA B O   1 
ATOM   3655 C CB  . ALA B 1 217 ? 27.18188  -65.11077 28.59232  1.000 70.08209  ? 177 ALA B CB  1 
ATOM   3656 N N   . LEU B 1 218 ? 30.53035  -64.65370 28.92282  1.000 64.07622  ? 178 LEU B N   1 
ATOM   3657 C CA  . LEU B 1 218 ? 31.63224  -63.70227 28.96128  1.000 66.74743  ? 178 LEU B CA  1 
ATOM   3658 C C   . LEU B 1 218 ? 31.84848  -63.08396 27.58766  1.000 64.27601  ? 178 LEU B C   1 
ATOM   3659 O O   . LEU B 1 218 ? 31.74058  -63.76668 26.56415  1.000 61.86936  ? 178 LEU B O   1 
ATOM   3660 C CB  . LEU B 1 218 ? 32.93027  -64.36913 29.42113  1.000 59.07365  ? 178 LEU B CB  1 
ATOM   3661 C CG  . LEU B 1 218 ? 32.97215  -64.98085 30.81823  1.000 60.81735  ? 178 LEU B CG  1 
ATOM   3662 C CD1 . LEU B 1 218 ? 34.39776  -65.38726 31.13615  1.000 49.34630  ? 178 LEU B CD1 1 
ATOM   3663 C CD2 . LEU B 1 218 ? 32.43850  -64.00754 31.85327  1.000 60.52029  ? 178 LEU B CD2 1 
ATOM   3664 N N   . ILE B 1 219 ? 32.14847  -61.78841 27.56914  1.000 64.11812  ? 179 ILE B N   1 
ATOM   3665 C CA  . ILE B 1 219 ? 32.60837  -61.10557 26.36511  1.000 64.29846  ? 179 ILE B CA  1 
ATOM   3666 C C   . ILE B 1 219 ? 34.13295  -61.05846 26.38444  1.000 65.55763  ? 179 ILE B C   1 
ATOM   3667 O O   . ILE B 1 219 ? 34.74048  -60.71355 27.40661  1.000 62.17327  ? 179 ILE B O   1 
ATOM   3668 C CB  . ILE B 1 219 ? 31.99424  -59.69725 26.25520  1.000 62.85277  ? 179 ILE B CB  1 
ATOM   3669 C CG1 . ILE B 1 219 ? 32.39510  -59.03608 24.93457  1.000 61.76957  ? 179 ILE B CG1 1 
ATOM   3670 C CG2 . ILE B 1 219 ? 32.34750  -58.83615 27.46497  1.000 63.74662  ? 179 ILE B CG2 1 
ATOM   3671 C CD1 . ILE B 1 219 ? 31.72158  -59.66411 23.73421  1.000 71.89876  ? 179 ILE B CD1 1 
ATOM   3672 N N   . ILE B 1 220 ? 34.75343  -61.44334 25.27246  1.000 58.64639  ? 180 ILE B N   1 
ATOM   3673 C CA  . ILE B 1 220 ? 36.20972  -61.53125 25.19043  1.000 58.75942  ? 180 ILE B CA  1 
ATOM   3674 C C   . ILE B 1 220 ? 36.71254  -60.80343 23.94924  1.000 57.77162  ? 180 ILE B C   1 
ATOM   3675 O O   . ILE B 1 220 ? 36.27912  -61.11043 22.83158  1.000 64.31108  ? 180 ILE B O   1 
ATOM   3676 C CB  . ILE B 1 220 ? 36.68583  -62.99220 25.19046  1.000 69.09868  ? 180 ILE B CB  1 
ATOM   3677 C CG1 . ILE B 1 220 ? 36.33914  -63.68248 26.51616  1.000 56.02034  ? 180 ILE B CG1 1 
ATOM   3678 C CG2 . ILE B 1 220 ? 38.18022  -63.07333 24.90277  1.000 65.07134  ? 180 ILE B CG2 1 
ATOM   3679 C CD1 . ILE B 1 220 ? 35.03077  -64.42915 26.49482  1.000 71.72520  ? 180 ILE B CD1 1 
ATOM   3680 N N   . PRO B 1 221 ? 37.62690  -59.84803 24.09172  1.000 55.18221  ? 181 PRO B N   1 
ATOM   3681 C CA  . PRO B 1 221 ? 38.16249  -59.15826 22.91333  1.000 61.41963  ? 181 PRO B CA  1 
ATOM   3682 C C   . PRO B 1 221 ? 39.24183  -59.98295 22.23002  1.000 62.67655  ? 181 PRO B C   1 
ATOM   3683 O O   . PRO B 1 221 ? 40.08488  -60.60742 22.87981  1.000 55.76397  ? 181 PRO B O   1 
ATOM   3684 C CB  . PRO B 1 221 ? 38.74063  -57.86685 23.50343  1.000 53.92455  ? 181 PRO B CB  1 
ATOM   3685 C CG  . PRO B 1 221 ? 39.19762  -58.27761 24.87079  1.000 43.81372  ? 181 PRO B CG  1 
ATOM   3686 C CD  . PRO B 1 221 ? 38.24107  -59.35973 25.34161  1.000 54.81632  ? 181 PRO B CD  1 
ATOM   3687 N N   . ILE B 1 222 ? 39.20575  -59.98289 20.89862  1.000 62.58238  ? 182 ILE B N   1 
ATOM   3688 C CA  . ILE B 1 222 ? 40.21422  -60.65051 20.09080  1.000 64.89445  ? 182 ILE B CA  1 
ATOM   3689 C C   . ILE B 1 222 ? 40.98522  -59.66630 19.22292  1.000 63.42983  ? 182 ILE B C   1 
ATOM   3690 O O   . ILE B 1 222 ? 41.75243  -60.07905 18.35266  1.000 61.61592  ? 182 ILE B O   1 
ATOM   3691 C CB  . ILE B 1 222 ? 39.59387  -61.76785 19.22963  1.000 68.54558  ? 182 ILE B CB  1 
ATOM   3692 C CG1 . ILE B 1 222 ? 38.50214  -61.20029 18.32555  1.000 67.31336  ? 182 ILE B CG1 1 
ATOM   3693 C CG2 . ILE B 1 222 ? 39.02836  -62.86714 20.11253  1.000 64.33611  ? 182 ILE B CG2 1 
ATOM   3694 C CD1 . ILE B 1 222 ? 37.97007  -62.18857 17.31121  1.000 62.80952  ? 182 ILE B CD1 1 
ATOM   3695 N N   . GLY B 1 223 ? 40.80081  -58.37641 19.44571  1.000 68.01560  ? 183 GLY B N   1 
ATOM   3696 C CA  . GLY B 1 223 ? 41.56130  -57.35911 18.75386  1.000 59.16586  ? 183 GLY B CA  1 
ATOM   3697 C C   . GLY B 1 223 ? 40.72648  -56.63181 17.71355  1.000 65.50031  ? 183 GLY B C   1 
ATOM   3698 O O   . GLY B 1 223 ? 39.72813  -57.13918 17.19480  1.000 67.35578  ? 183 GLY B O   1 
ATOM   3699 N N   . THR B 1 224 ? 41.17978  -55.41936 17.39310  1.000 68.11911  ? 184 THR B N   1 
ATOM   3700 C CA  . THR B 1 224 ? 40.57232  -54.55651 16.37670  1.000 65.49693  ? 184 THR B CA  1 
ATOM   3701 C C   . THR B 1 224 ? 39.04622  -54.53925 16.46300  1.000 58.65366  ? 184 THR B C   1 
ATOM   3702 O O   . THR B 1 224 ? 38.33752  -54.62811 15.45859  1.000 60.55944  ? 184 THR B O   1 
ATOM   3703 C CB  . THR B 1 224 ? 41.03641  -54.96197 14.97559  1.000 63.00805  ? 184 THR B CB  1 
ATOM   3704 O OG1 . THR B 1 224 ? 40.64143  -56.31115 14.70073  1.000 68.15485  ? 184 THR B OG1 1 
ATOM   3705 C CG2 . THR B 1 224 ? 42.54515  -54.85360 14.88704  1.000 60.35003  ? 184 THR B CG2 1 
ATOM   3706 N N   . GLY B 1 225 ? 38.54028  -54.42132 17.69105  1.000 53.25591  ? 185 GLY B N   1 
ATOM   3707 C CA  . GLY B 1 225 ? 37.12178  -54.27380 17.92900  1.000 62.21817  ? 185 GLY B CA  1 
ATOM   3708 C C   . GLY B 1 225 ? 36.29553  -55.53439 17.80632  1.000 63.28091  ? 185 GLY B C   1 
ATOM   3709 O O   . GLY B 1 225 ? 35.09474  -55.49742 18.10329  1.000 55.73053  ? 185 GLY B O   1 
ATOM   3710 N N   . LEU B 1 226 ? 36.88207  -56.64329 17.37818  1.000 56.62825  ? 186 LEU B N   1 
ATOM   3711 C CA  . LEU B 1 226 ? 36.15438  -57.89568 17.27254  1.000 65.22413  ? 186 LEU B CA  1 
ATOM   3712 C C   . LEU B 1 226 ? 36.14597  -58.61789 18.61231  1.000 70.53570  ? 186 LEU B C   1 
ATOM   3713 O O   . LEU B 1 226 ? 37.07625  -58.49424 19.41322  1.000 71.23810  ? 186 LEU B O   1 
ATOM   3714 C CB  . LEU B 1 226 ? 36.76643  -58.78837 16.19447  1.000 69.69977  ? 186 LEU B CB  1 
ATOM   3715 C CG  . LEU B 1 226 ? 36.91197  -58.12890 14.82267  1.000 67.05321  ? 186 LEU B CG  1 
ATOM   3716 C CD1 . LEU B 1 226 ? 37.60636  -59.06617 13.85261  1.000 60.43855  ? 186 LEU B CD1 1 
ATOM   3717 C CD2 . LEU B 1 226 ? 35.55575  -57.70032 14.28606  1.000 52.07899  ? 186 LEU B CD2 1 
ATOM   3718 N N   . HIS B 1 227 ? 35.07566  -59.37288 18.85306  1.000 66.51474  ? 187 HIS B N   1 
ATOM   3719 C CA  . HIS B 1 227 ? 34.88329  -60.04172 20.13089  1.000 67.36955  ? 187 HIS B CA  1 
ATOM   3720 C C   . HIS B 1 227 ? 34.38461  -61.46552 19.93229  1.000 74.77338  ? 187 HIS B C   1 
ATOM   3721 O O   . HIS B 1 227 ? 33.59152  -61.73789 19.02635  1.000 76.38089  ? 187 HIS B O   1 
ATOM   3722 C CB  . HIS B 1 227 ? 33.89424  -59.27018 21.01011  1.000 56.59500  ? 187 HIS B CB  1 
ATOM   3723 C CG  . HIS B 1 227 ? 34.38198  -57.91863 21.42755  1.000 59.88253  ? 187 HIS B CG  1 
ATOM   3724 N ND1 . HIS B 1 227 ? 34.15662  -56.78346 20.68048  1.000 57.72107  ? 187 HIS B ND1 1 
ATOM   3725 C CD2 . HIS B 1 227 ? 35.06775  -57.51719 22.52440  1.000 62.15234  ? 187 HIS B CD2 1 
ATOM   3726 C CE1 . HIS B 1 227 ? 34.69481  -55.74291 21.29167  1.000 60.52542  ? 187 HIS B CE1 1 
ATOM   3727 N NE2 . HIS B 1 227 ? 35.25234  -56.16051 22.41372  1.000 50.53628  ? 187 HIS B NE2 1 
ATOM   3728 N N   . ARG B 1 228 ? 34.85192  -62.36622 20.79292  1.000 70.89377  ? 188 ARG B N   1 
ATOM   3729 C CA  . ARG B 1 228 ? 34.36696  -63.73628 20.85717  1.000 80.50226  ? 188 ARG B CA  1 
ATOM   3730 C C   . ARG B 1 228 ? 33.58085  -63.93466 22.14837  1.000 80.67575  ? 188 ARG B C   1 
ATOM   3731 O O   . ARG B 1 228 ? 33.83231  -63.26736 23.15639  1.000 76.28263  ? 188 ARG B O   1 
ATOM   3732 C CB  . ARG B 1 228 ? 35.51571  -64.75152 20.77313  1.000 66.32980  ? 188 ARG B CB  1 
ATOM   3733 C CG  . ARG B 1 228 ? 36.25018  -65.00921 22.08042  1.000 74.57540  ? 188 ARG B CG  1 
ATOM   3734 C CD  . ARG B 1 228 ? 37.05540  -66.29864 22.00326  1.000 69.95270  ? 188 ARG B CD  1 
ATOM   3735 N NE  . ARG B 1 228 ? 38.22655  -66.16816 21.14476  1.000 68.74284  ? 188 ARG B NE  1 
ATOM   3736 C CZ  . ARG B 1 228 ? 39.46585  -66.01171 21.59027  1.000 83.93185  ? 188 ARG B CZ  1 
ATOM   3737 N NH1 . ARG B 1 228 ? 39.73194  -65.95592 22.88429  1.000 79.27727  ? 188 ARG B NH1 1 
ATOM   3738 N NH2 . ARG B 1 228 ? 40.46269  -65.90321 20.71541  1.000 64.70828  ? 188 ARG B NH2 1 
ATOM   3739 N N   . ARG B 1 229 ? 32.61504  -64.84830 22.10722  1.000 87.43088  ? 189 ARG B N   1 
ATOM   3740 C CA  . ARG B 1 229 ? 31.76052  -65.14296 23.24849  1.000 73.13414  ? 189 ARG B CA  1 
ATOM   3741 C C   . ARG B 1 229 ? 32.12952  -66.50187 23.82566  1.000 72.49860  ? 189 ARG B C   1 
ATOM   3742 O O   . ARG B 1 229 ? 32.38699  -67.45348 23.08217  1.000 75.51149  ? 189 ARG B O   1 
ATOM   3743 C CB  . ARG B 1 229 ? 30.28358  -65.13956 22.84388  1.000 77.42628  ? 189 ARG B CB  1 
ATOM   3744 C CG  . ARG B 1 229 ? 29.86032  -63.93261 22.02286  1.000 91.12889  ? 189 ARG B CG  1 
ATOM   3745 C CD  . ARG B 1 229 ? 29.61525  -62.71532 22.89615  1.000 99.39850  ? 189 ARG B CD  1 
ATOM   3746 N NE  . ARG B 1 229 ? 28.19914  -62.37360 22.95576  1.000 104.42041 ? 189 ARG B NE  1 
ATOM   3747 C CZ  . ARG B 1 229 ? 27.58511  -61.57201 22.09613  1.000 104.55787 ? 189 ARG B CZ  1 
ATOM   3748 N NH1 . ARG B 1 229 ? 28.23733  -60.99945 21.09707  1.000 98.28418  ? 189 ARG B NH1 1 
ATOM   3749 N NH2 . ARG B 1 229 ? 26.28469  -61.33639 22.24450  1.000 98.95834  ? 189 ARG B NH2 1 
ATOM   3750 N N   . MET B 1 230 ? 32.17243  -66.58583 25.15319  1.000 64.17378  ? 190 MET B N   1 
ATOM   3751 C CA  . MET B 1 230 ? 32.42433  -67.84514 25.84158  1.000 76.75322  ? 190 MET B CA  1 
ATOM   3752 C C   . MET B 1 230 ? 31.34735  -68.04801 26.89396  1.000 80.24321  ? 190 MET B C   1 
ATOM   3753 O O   . MET B 1 230 ? 31.15395  -67.19123 27.76288  1.000 70.29350  ? 190 MET B O   1 
ATOM   3754 C CB  . MET B 1 230 ? 33.82132  -67.85735 26.46320  1.000 71.39969  ? 190 MET B CB  1 
ATOM   3755 C CG  . MET B 1 230 ? 34.59426  -69.13348 26.19303  1.000 89.88582  ? 190 MET B CG  1 
ATOM   3756 S SD  . MET B 1 230 ? 36.28232  -69.06286 26.82391  1.000 116.63873 ? 190 MET B SD  1 
ATOM   3757 C CE  . MET B 1 230 ? 37.06030  -68.04300 25.57083  1.000 63.70147  ? 190 MET B CE  1 
ATOM   3758 N N   . VAL B 1 231 ? 30.65796  -69.18255 26.81807  1.000 86.00740  ? 191 VAL B N   1 
ATOM   3759 C CA  . VAL B 1 231 ? 29.49880  -69.46951 27.65301  1.000 79.85709  ? 191 VAL B CA  1 
ATOM   3760 C C   . VAL B 1 231 ? 29.82561  -70.66802 28.52926  1.000 76.99736  ? 191 VAL B C   1 
ATOM   3761 O O   . VAL B 1 231 ? 30.20046  -71.73269 28.02159  1.000 80.41960  ? 191 VAL B O   1 
ATOM   3762 C CB  . VAL B 1 231 ? 28.24190  -69.73387 26.81082  1.000 78.69380  ? 191 VAL B CB  1 
ATOM   3763 C CG1 . VAL B 1 231 ? 27.00241  -69.69877 27.68765  1.000 81.63412  ? 191 VAL B CG1 1 
ATOM   3764 C CG2 . VAL B 1 231 ? 28.13885  -68.71974 25.67922  1.000 77.83849  ? 191 VAL B CG2 1 
ATOM   3765 N N   . TYR B 1 232 ? 29.68981  -70.49220 29.83916  1.000 77.70832  ? 192 TYR B N   1 
ATOM   3766 C CA  . TYR B 1 232 ? 29.81967  -71.57241 30.80702  1.000 80.12468  ? 192 TYR B CA  1 
ATOM   3767 C C   . TYR B 1 232 ? 28.42412  -71.92219 31.29934  1.000 87.47627  ? 192 TYR B C   1 
ATOM   3768 O O   . TYR B 1 232 ? 27.70554  -71.05020 31.79970  1.000 80.22860  ? 192 TYR B O   1 
ATOM   3769 C CB  . TYR B 1 232 ? 30.71876  -71.15755 31.96943  1.000 58.56886  ? 192 TYR B CB  1 
ATOM   3770 C CG  . TYR B 1 232 ? 32.06636  -70.65631 31.51842  1.000 66.62988  ? 192 TYR B CG  1 
ATOM   3771 C CD1 . TYR B 1 232 ? 33.10335  -71.53841 31.25820  1.000 64.29029  ? 192 TYR B CD1 1 
ATOM   3772 C CD2 . TYR B 1 232 ? 32.29818  -69.29790 31.33639  1.000 66.61926  ? 192 TYR B CD2 1 
ATOM   3773 C CE1 . TYR B 1 232 ? 34.33770  -71.08512 30.83595  1.000 69.88477  ? 192 TYR B CE1 1 
ATOM   3774 C CE2 . TYR B 1 232 ? 33.52725  -68.83550 30.91653  1.000 56.28017  ? 192 TYR B CE2 1 
ATOM   3775 C CZ  . TYR B 1 232 ? 34.54363  -69.73324 30.66769  1.000 62.17405  ? 192 TYR B CZ  1 
ATOM   3776 O OH  . TYR B 1 232 ? 35.77082  -69.27740 30.24777  1.000 80.39749  ? 192 TYR B OH  1 
ATOM   3777 N N   . VAL B 1 233 ? 28.04133  -73.18821 31.16272  1.000 88.97911  ? 193 VAL B N   1 
ATOM   3778 C CA  . VAL B 1 233 ? 26.66880  -73.61217 31.40265  1.000 92.19562  ? 193 VAL B CA  1 
ATOM   3779 C C   . VAL B 1 233 ? 26.65261  -74.67740 32.48805  1.000 87.67615  ? 193 VAL B C   1 
ATOM   3780 O O   . VAL B 1 233 ? 27.44736  -75.62536 32.45739  1.000 79.35947  ? 193 VAL B O   1 
ATOM   3781 C CB  . VAL B 1 233 ? 26.00187  -74.13149 30.11546  1.000 89.35778  ? 193 VAL B CB  1 
ATOM   3782 C CG1 . VAL B 1 233 ? 25.60456  -72.96624 29.22603  1.000 85.76482  ? 193 VAL B CG1 1 
ATOM   3783 C CG2 . VAL B 1 233 ? 26.93446  -75.07852 29.37286  1.000 89.44137  ? 193 VAL B CG2 1 
ATOM   3784 N N   . GLU B 1 234 ? 25.75339  -74.50337 33.45027  1.000 84.00403  ? 194 GLU B N   1 
ATOM   3785 C CA  . GLU B 1 234 ? 25.43084  -75.51345 34.44876  1.000 97.16785  ? 194 GLU B CA  1 
ATOM   3786 C C   . GLU B 1 234 ? 24.17693  -76.21826 33.95006  1.000 104.66275 ? 194 GLU B C   1 
ATOM   3787 O O   . GLU B 1 234 ? 23.10193  -75.61282 33.89509  1.000 101.96465 ? 194 GLU B O   1 
ATOM   3788 C CB  . GLU B 1 234 ? 25.20677  -74.87408 35.81784  1.000 90.02283  ? 194 GLU B CB  1 
ATOM   3789 C CG  . GLU B 1 234 ? 25.10082  -75.85043 36.97607  1.000 89.72946  ? 194 GLU B CG  1 
ATOM   3790 C CD  . GLU B 1 234 ? 25.04654  -75.14735 38.32137  1.000 84.57898  ? 194 GLU B CD  1 
ATOM   3791 O OE1 . GLU B 1 234 ? 25.35860  -73.94036 38.36920  1.000 81.90026  ? 194 GLU B OE1 1 
ATOM   3792 O OE2 . GLU B 1 234 ? 24.69238  -75.79787 39.32823  1.000 102.29837 ? 194 GLU B OE2 1 
ATOM   3793 N N   . LEU B 1 235 ? 24.30869  -77.48473 33.57318  1.000 103.18601 ? 195 LEU B N   1 
ATOM   3794 C CA  . LEU B 1 235 ? 23.20465  -78.15333 32.90589  1.000 111.99576 ? 195 LEU B CA  1 
ATOM   3795 C C   . LEU B 1 235 ? 22.19271  -78.68068 33.91389  1.000 110.51869 ? 195 LEU B C   1 
ATOM   3796 O O   . LEU B 1 235 ? 22.51438  -78.94005 35.07816  1.000 112.12974 ? 195 LEU B O   1 
ATOM   3797 C CB  . LEU B 1 235 ? 23.72396  -79.30613 32.04581  1.000 105.69514 ? 195 LEU B CB  1 
ATOM   3798 C CG  . LEU B 1 235 ? 23.47003  -79.18113 30.54474  1.000 110.11943 ? 195 LEU B CG  1 
ATOM   3799 C CD1 . LEU B 1 235 ? 23.91862  -77.81684 30.05695  1.000 118.81310 ? 195 LEU B CD1 1 
ATOM   3800 C CD2 . LEU B 1 235 ? 24.18476  -80.28455 29.78617  1.000 106.54045 ? 195 LEU B CD2 1 
ATOM   3801 N N   . GLU B 1 236 ? 20.95471  -78.83191 33.45031  1.000 109.75064 ? 196 GLU B N   1 
ATOM   3802 C CA  . GLU B 1 236 ? 19.91657  -79.44769 34.25764  1.000 106.43231 ? 196 GLU B CA  1 
ATOM   3803 C C   . GLU B 1 236 ? 20.07050  -80.96139 34.19407  1.000 113.64381 ? 196 GLU B C   1 
ATOM   3804 O O   . GLU B 1 236 ? 20.47821  -81.52131 33.17106  1.000 111.15566 ? 196 GLU B O   1 
ATOM   3805 C CB  . GLU B 1 236 ? 18.52680  -79.01891 33.78090  1.000 86.56168  ? 196 GLU B CB  1 
ATOM   3806 C CG  . GLU B 1 236 ? 17.82696  -78.03103 34.71540  1.000 75.37763  ? 196 GLU B CG  1 
ATOM   3807 C CD  . GLU B 1 236 ? 17.19354  -76.85988 33.98285  1.000 96.24240  ? 196 GLU B CD  1 
ATOM   3808 O OE1 . GLU B 1 236 ? 17.01778  -76.94373 32.74801  1.000 96.29754  ? 196 GLU B OE1 1 
ATOM   3809 O OE2 . GLU B 1 236 ? 16.86738  -75.84940 34.64519  1.000 90.19229  ? 196 GLU B OE2 1 
ATOM   3810 N N   . GLU B 1 237 ? 19.76125  -81.61902 35.30873  1.000 114.82587 ? 197 GLU B N   1 
ATOM   3811 C CA  . GLU B 1 237 ? 20.02248  -83.04710 35.44192  1.000 118.57930 ? 197 GLU B CA  1 
ATOM   3812 C C   . GLU B 1 237 ? 19.30165  -83.82212 34.34808  1.000 117.17032 ? 197 GLU B C   1 
ATOM   3813 O O   . GLU B 1 237 ? 18.07656  -83.75585 34.24070  1.000 101.52366 ? 197 GLU B O   1 
ATOM   3814 C CB  . GLU B 1 237 ? 19.56660  -83.53247 36.81595  1.000 117.01952 ? 197 GLU B CB  1 
ATOM   3815 C CG  . GLU B 1 237 ? 20.22433  -84.82777 37.23882  1.000 116.42325 ? 197 GLU B CG  1 
ATOM   3816 C CD  . GLU B 1 237 ? 19.27347  -85.77028 37.94281  1.000 130.90617 ? 197 GLU B CD  1 
ATOM   3817 O OE1 . GLU B 1 237 ? 18.32227  -85.29253 38.59680  1.000 128.66028 ? 197 GLU B OE1 1 
ATOM   3818 O OE2 . GLU B 1 237 ? 19.47787  -86.99619 37.83284  1.000 130.07243 ? 197 GLU B OE2 1 
ATOM   3819 N N   . GLY B 1 238 ? 20.04625  -84.55283 33.52563  1.000 109.60628 ? 198 GLY B N   1 
ATOM   3820 C CA  . GLY B 1 238 ? 19.37201  -85.31849 32.49456  1.000 107.30809 ? 198 GLY B CA  1 
ATOM   3821 C C   . GLY B 1 238 ? 19.39233  -84.71593 31.10412  1.000 116.89999 ? 198 GLY B C   1 
ATOM   3822 O O   . GLY B 1 238 ? 18.67198  -85.18302 30.21369  1.000 114.92541 ? 198 GLY B O   1 
ATOM   3823 N N   . ALA B 1 239 ? 20.25321  -83.72730 30.88113  1.000 119.48718 ? 199 ALA B N   1 
ATOM   3824 C CA  . ALA B 1 239 ? 20.38098  -83.08854 29.57980  1.000 102.40700 ? 199 ALA B CA  1 
ATOM   3825 C C   . ALA B 1 239 ? 21.68587  -83.46232 28.88521  1.000 108.96695 ? 199 ALA B C   1 
ATOM   3826 O O   . ALA B 1 239 ? 22.68033  -83.81092 29.53052  1.000 112.70481 ? 199 ALA B O   1 
ATOM   3827 C CB  . ALA B 1 239 ? 20.30475  -81.56882 29.70723  1.000 100.04980 ? 199 ALA B CB  1 
ATOM   3828 N N   . ASP B 1 240 ? 21.65242  -83.41226 27.55003  1.000 109.92637 ? 200 ASP B N   1 
ATOM   3829 C CA  . ASP B 1 240 ? 22.80720  -83.71122 26.71205  1.000 115.31016 ? 200 ASP B CA  1 
ATOM   3830 C C   . ASP B 1 240 ? 23.55701  -82.42254 26.40161  1.000 122.94637 ? 200 ASP B C   1 
ATOM   3831 O O   . ASP B 1 240 ? 22.94882  -81.40326 26.06315  1.000 120.36528 ? 200 ASP B O   1 
ATOM   3832 C CB  . ASP B 1 240 ? 22.36898  -84.38410 25.40783  1.000 101.43983 ? 200 ASP B CB  1 
ATOM   3833 C CG  . ASP B 1 240 ? 23.53794  -84.68803 24.48069  1.000 116.57628 ? 200 ASP B CG  1 
ATOM   3834 O OD1 . ASP B 1 240 ? 24.47093  -85.38951 24.91322  1.000 116.28187 ? 200 ASP B OD1 1 
ATOM   3835 O OD2 . ASP B 1 240 ? 23.51614  -84.23643 23.31469  1.000 119.39830 ? 200 ASP B OD2 1 
ATOM   3836 N N   . PHE B 1 241 ? 24.88804  -82.47879 26.50519  1.000 125.09282 ? 201 PHE B N   1 
ATOM   3837 C CA  . PHE B 1 241 ? 25.69124  -81.27788 26.29085  1.000 122.61811 ? 201 PHE B CA  1 
ATOM   3838 C C   . PHE B 1 241 ? 25.67832  -80.84637 24.82956  1.000 120.87585 ? 201 PHE B C   1 
ATOM   3839 O O   . PHE B 1 241 ? 25.56380  -79.65195 24.53171  1.000 120.32494 ? 201 PHE B O   1 
ATOM   3840 C CB  . PHE B 1 241 ? 27.12413  -81.50456 26.76816  1.000 114.03869 ? 201 PHE B CB  1 
ATOM   3841 C CG  . PHE B 1 241 ? 27.97773  -80.27063 26.71076  1.000 112.38992 ? 201 PHE B CG  1 
ATOM   3842 C CD1 . PHE B 1 241 ? 27.57098  -79.10515 27.33926  1.000 108.94151 ? 201 PHE B CD1 1 
ATOM   3843 C CD2 . PHE B 1 241 ? 29.18048  -80.27113 26.02361  1.000 109.90780 ? 201 PHE B CD2 1 
ATOM   3844 C CE1 . PHE B 1 241 ? 28.34851  -77.96426 27.29039  1.000 104.24975 ? 201 PHE B CE1 1 
ATOM   3845 C CE2 . PHE B 1 241 ? 29.96408  -79.13098 25.97024  1.000 106.30917 ? 201 PHE B CE2 1 
ATOM   3846 C CZ  . PHE B 1 241 ? 29.54672  -77.97692 26.60478  1.000 106.27361 ? 201 PHE B CZ  1 
ATOM   3847 N N   . ALA B 1 242 ? 25.82423  -81.79950 23.90518  1.000 111.80662 ? 202 ALA B N   1 
ATOM   3848 C CA  . ALA B 1 242 ? 25.84622  -81.45922 22.48614  1.000 106.86381 ? 202 ALA B CA  1 
ATOM   3849 C C   . ALA B 1 242 ? 24.53022  -80.83125 22.04750  1.000 114.33562 ? 202 ALA B C   1 
ATOM   3850 O O   . ALA B 1 242 ? 24.51691  -79.95493 21.17538  1.000 108.20309 ? 202 ALA B O   1 
ATOM   3851 C CB  . ALA B 1 242 ? 26.15517  -82.70076 21.64867  1.000 105.28667 ? 202 ALA B CB  1 
ATOM   3852 N N   . THR B 1 243 ? 23.41837  -81.26071 22.64803  1.000 115.08415 ? 203 THR B N   1 
ATOM   3853 C CA  . THR B 1 243 ? 22.10926  -80.74306 22.26557  1.000 113.06025 ? 203 THR B CA  1 
ATOM   3854 C C   . THR B 1 243 ? 21.90861  -79.32122 22.77354  1.000 108.44548 ? 203 THR B C   1 
ATOM   3855 O O   . THR B 1 243 ? 21.49044  -78.43541 22.01881  1.000 109.60027 ? 203 THR B O   1 
ATOM   3856 C CB  . THR B 1 243 ? 21.01470  -81.66327 22.80600  1.000 108.00570 ? 203 THR B CB  1 
ATOM   3857 O OG1 . THR B 1 243 ? 21.25581  -83.00606 22.36575  1.000 99.14877  ? 203 THR B OG1 1 
ATOM   3858 C CG2 . THR B 1 243 ? 19.64561  -81.20808 22.32470  1.000 89.32755  ? 203 THR B CG2 1 
ATOM   3859 N N   . VAL B 1 244 ? 22.19455  -79.08482 24.05545  1.000 112.17407 ? 204 VAL B N   1 
ATOM   3860 C CA  . VAL B 1 244 ? 22.06758  -77.73816 24.60194  1.000 115.71070 ? 204 VAL B CA  1 
ATOM   3861 C C   . VAL B 1 244 ? 23.06064  -76.79460 23.93263  1.000 111.77777 ? 204 VAL B C   1 
ATOM   3862 O O   . VAL B 1 244 ? 22.81574  -75.58590 23.84299  1.000 102.31999 ? 204 VAL B O   1 
ATOM   3863 C CB  . VAL B 1 244 ? 22.23473  -77.75607 26.13347  1.000 111.83429 ? 204 VAL B CB  1 
ATOM   3864 C CG1 . VAL B 1 244 ? 21.19261  -78.66128 26.76541  1.000 115.79590 ? 204 VAL B CG1 1 
ATOM   3865 C CG2 . VAL B 1 244 ? 23.62994  -78.20442 26.51667  1.000 105.48628 ? 204 VAL B CG2 1 
ATOM   3866 N N   . LYS B 1 245 ? 24.19613  -77.32198 23.46675  1.000 109.51254 ? 205 LYS B N   1 
ATOM   3867 C CA  . LYS B 1 245 ? 25.14979  -76.51294 22.71282  1.000 107.49724 ? 205 LYS B CA  1 
ATOM   3868 C C   . LYS B 1 245 ? 24.53467  -75.94121 21.43654  1.000 119.60482 ? 205 LYS B C   1 
ATOM   3869 O O   . LYS B 1 245 ? 24.82270  -74.79817 21.06470  1.000 116.81038 ? 205 LYS B O   1 
ATOM   3870 C CB  . LYS B 1 245 ? 26.39699  -77.33788 22.38726  1.000 93.14827  ? 205 LYS B CB  1 
ATOM   3871 C CG  . LYS B 1 245 ? 27.55214  -77.12309 23.35693  1.000 96.30576  ? 205 LYS B CG  1 
ATOM   3872 C CD  . LYS B 1 245 ? 28.86478  -77.67434 22.80866  1.000 97.21274  ? 205 LYS B CD  1 
ATOM   3873 C CE  . LYS B 1 245 ? 29.18206  -77.09141 21.43928  1.000 90.79288  ? 205 LYS B CE  1 
ATOM   3874 N NZ  . LYS B 1 245 ? 30.50971  -77.52092 20.91604  1.000 95.07010  ? 205 LYS B NZ  1 
ATOM   3875 N N   . GLU B 1 246 ? 23.68710  -76.71444 20.74735  1.000 118.23927 ? 206 GLU B N   1 
ATOM   3876 C CA  . GLU B 1 246 ? 23.15110  -76.26458 19.46317  1.000 112.57231 ? 206 GLU B CA  1 
ATOM   3877 C C   . GLU B 1 246 ? 21.98478  -75.28929 19.58266  1.000 111.26594 ? 206 GLU B C   1 
ATOM   3878 O O   . GLU B 1 246 ? 21.58359  -74.70061 18.57291  1.000 120.85948 ? 206 GLU B O   1 
ATOM   3879 C CB  . GLU B 1 246 ? 22.69631  -77.46944 18.63917  1.000 117.36529 ? 206 GLU B CB  1 
ATOM   3880 C CG  . GLU B 1 246 ? 23.76378  -78.52504 18.43559  1.000 126.55015 ? 206 GLU B CG  1 
ATOM   3881 C CD  . GLU B 1 246 ? 25.08689  -77.93966 18.00629  1.000 124.69819 ? 206 GLU B CD  1 
ATOM   3882 O OE1 . GLU B 1 246 ? 25.10229  -77.20111 16.99987  1.000 127.66956 ? 206 GLU B OE1 1 
ATOM   3883 O OE2 . GLU B 1 246 ? 26.11181  -78.22781 18.66067  1.000 106.91844 ? 206 GLU B OE2 1 
ATOM   3884 N N   . ARG B 1 247 ? 21.47095  -75.05008 20.78391  1.000 105.19647 ? 207 ARG B N   1 
ATOM   3885 C CA  . ARG B 1 247 ? 20.48156  -73.99531 20.95830  1.000 108.94463 ? 207 ARG B CA  1 
ATOM   3886 C C   . ARG B 1 247 ? 21.12673  -72.73931 21.50647  1.000 118.06729 ? 207 ARG B C   1 
ATOM   3887 O O   . ARG B 1 247 ? 20.53671  -71.65560 21.42301  1.000 117.83834 ? 207 ARG B O   1 
ATOM   3888 C CB  . ARG B 1 247 ? 19.29916  -74.43421 21.83635  1.000 110.50919 ? 207 ARG B CB  1 
ATOM   3889 C CG  . ARG B 1 247 ? 18.31718  -75.38151 21.13908  1.000 117.60576 ? 207 ARG B CG  1 
ATOM   3890 C CD  . ARG B 1 247 ? 17.30767  -76.00288 22.10527  1.000 122.63221 ? 207 ARG B CD  1 
ATOM   3891 N NE  . ARG B 1 247 ? 16.31993  -76.81745 21.40269  1.000 131.66329 ? 207 ARG B NE  1 
ATOM   3892 C CZ  . ARG B 1 247 ? 15.09713  -76.40597 21.08856  1.000 132.45282 ? 207 ARG B CZ  1 
ATOM   3893 N NH1 . ARG B 1 247 ? 14.67311  -75.19274 21.40363  1.000 123.85974 ? 207 ARG B NH1 1 
ATOM   3894 N NH2 . ARG B 1 247 ? 14.28049  -77.23020 20.43736  1.000 139.40816 ? 207 ARG B NH2 1 
ATOM   3895 N N   . ILE B 1 248 ? 22.31363  -72.88402 22.08736  1.000 121.62341 ? 208 ILE B N   1 
ATOM   3896 C CA  . ILE B 1 248 ? 23.11718  -71.73607 22.46843  1.000 118.78373 ? 208 ILE B CA  1 
ATOM   3897 C C   . ILE B 1 248 ? 23.86074  -71.19688 21.25371  1.000 114.68903 ? 208 ILE B C   1 
ATOM   3898 O O   . ILE B 1 248 ? 23.90544  -69.98334 21.02638  1.000 122.83020 ? 208 ILE B O   1 
ATOM   3899 C CB  . ILE B 1 248 ? 24.08520  -72.14888 23.58920  1.000 107.59133 ? 208 ILE B CB  1 
ATOM   3900 C CG1 . ILE B 1 248 ? 23.30778  -72.49326 24.85969  1.000 106.72569 ? 208 ILE B CG1 1 
ATOM   3901 C CG2 . ILE B 1 248 ? 25.10407  -71.05586 23.83855  1.000 97.44455  ? 208 ILE B CG2 1 
ATOM   3902 C CD1 . ILE B 1 248 ? 24.17141  -73.07750 25.94679  1.000 84.07130  ? 208 ILE B CD1 1 
ATOM   3903 N N   . LEU B 1 249 ? 24.43441  -72.09017 20.44136  1.000 106.92756 ? 209 LEU B N   1 
ATOM   3904 C CA  . LEU B 1 249 ? 25.16011  -71.67220 19.24662  1.000 102.54395 ? 209 LEU B CA  1 
ATOM   3905 C C   . LEU B 1 249 ? 24.24775  -71.15738 18.13932  1.000 114.95778 ? 209 LEU B C   1 
ATOM   3906 O O   . LEU B 1 249 ? 24.72427  -70.44836 17.24815  1.000 109.70455 ? 209 LEU B O   1 
ATOM   3907 C CB  . LEU B 1 249 ? 26.00850  -72.82626 18.71407  1.000 99.45189  ? 209 LEU B CB  1 
ATOM   3908 C CG  . LEU B 1 249 ? 27.48625  -72.77455 19.09685  1.000 103.41962 ? 209 LEU B CG  1 
ATOM   3909 C CD1 . LEU B 1 249 ? 28.20625  -74.03784 18.64754  1.000 88.28274  ? 209 LEU B CD1 1 
ATOM   3910 C CD2 . LEU B 1 249 ? 28.15329  -71.53235 18.52314  1.000 104.47499 ? 209 LEU B CD2 1 
ATOM   3911 N N   . GLN B 1 250 ? 22.95826  -71.48985 18.16243  1.000 113.75223 ? 210 GLN B N   1 
ATOM   3912 C CA  . GLN B 1 250 ? 22.01514  -70.95764 17.18363  1.000 110.61628 ? 210 GLN B CA  1 
ATOM   3913 C C   . GLN B 1 250 ? 21.06904  -69.91055 17.75918  1.000 109.27189 ? 210 GLN B C   1 
ATOM   3914 O O   . GLN B 1 250 ? 20.10803  -69.51950 17.08537  1.000 107.21497 ? 210 GLN B O   1 
ATOM   3915 C CB  . GLN B 1 250 ? 21.22151  -72.08620 16.51933  1.000 113.11239 ? 210 GLN B CB  1 
ATOM   3916 C CG  . GLN B 1 250 ? 21.98160  -72.81165 15.40547  1.000 119.94884 ? 210 GLN B CG  1 
ATOM   3917 C CD  . GLN B 1 250 ? 22.89245  -73.93386 15.88209  1.000 122.41373 ? 210 GLN B CD  1 
ATOM   3918 O OE1 . GLN B 1 250 ? 22.44655  -75.06295 16.12290  1.000 117.58388 ? 210 GLN B OE1 1 
ATOM   3919 N NE2 . GLN B 1 250 ? 24.17355  -73.63242 16.00825  1.000 114.39770 ? 210 GLN B NE2 1 
ATOM   3920 N N   . ASP B 1 251 ? 21.29912  -69.46382 18.98529  1.000 110.27566 ? 211 ASP B N   1 
ATOM   3921 C CA  . ASP B 1 251 ? 20.57647  -68.30688 19.48422  1.000 111.62308 ? 211 ASP B CA  1 
ATOM   3922 C C   . ASP B 1 251 ? 21.03471  -67.07351 18.70795  1.000 121.00558 ? 211 ASP B C   1 
ATOM   3923 O O   . ASP B 1 251 ? 22.21219  -66.98019 18.34864  1.000 116.37162 ? 211 ASP B O   1 
ATOM   3924 C CB  . ASP B 1 251 ? 20.83621  -68.12677 20.98024  1.000 107.12572 ? 211 ASP B CB  1 
ATOM   3925 C CG  . ASP B 1 251 ? 19.92908  -67.09425 21.61632  1.000 117.36860 ? 211 ASP B CG  1 
ATOM   3926 O OD1 . ASP B 1 251 ? 18.77874  -67.44512 21.94912  1.000 110.31209 ? 211 ASP B OD1 1 
ATOM   3927 O OD2 . ASP B 1 251 ? 20.36159  -65.93304 21.77810  1.000 121.01491 ? 211 ASP B OD2 1 
ATOM   3928 N N   . PRO B 1 252 ? 20.13504  -66.12457 18.41750  1.000 121.35301 ? 212 PRO B N   1 
ATOM   3929 C CA  . PRO B 1 252 ? 20.52223  -64.97450 17.57501  1.000 118.54133 ? 212 PRO B CA  1 
ATOM   3930 C C   . PRO B 1 252 ? 21.73411  -64.19984 18.07557  1.000 117.73203 ? 212 PRO B C   1 
ATOM   3931 O O   . PRO B 1 252 ? 22.39337  -63.52860 17.27174  1.000 113.53742 ? 212 PRO B O   1 
ATOM   3932 C CB  . PRO B 1 252 ? 19.25957  -64.09764 17.57493  1.000 116.55133 ? 212 PRO B CB  1 
ATOM   3933 C CG  . PRO B 1 252 ? 18.43615  -64.58803 18.73450  1.000 116.51163 ? 212 PRO B CG  1 
ATOM   3934 C CD  . PRO B 1 252 ? 18.71575  -66.05517 18.80455  1.000 112.12148 ? 212 PRO B CD  1 
ATOM   3935 N N   . LEU B 1 253 ? 22.04698  -64.25808 19.36934  1.000 112.28538 ? 213 LEU B N   1 
ATOM   3936 C CA  . LEU B 1 253 ? 23.18229  -63.50890 19.89326  1.000 113.02327 ? 213 LEU B CA  1 
ATOM   3937 C C   . LEU B 1 253 ? 24.52151  -64.18992 19.62539  1.000 110.69511 ? 213 LEU B C   1 
ATOM   3938 O O   . LEU B 1 253 ? 25.55988  -63.52339 19.69563  1.000 114.40665 ? 213 LEU B O   1 
ATOM   3939 C CB  . LEU B 1 253 ? 23.01373  -63.26271 21.39493  1.000 111.36439 ? 213 LEU B CB  1 
ATOM   3940 C CG  . LEU B 1 253 ? 22.34489  -61.93325 21.76157  1.000 108.55027 ? 213 LEU B CG  1 
ATOM   3941 C CD1 . LEU B 1 253 ? 20.91437  -61.86350 21.23978  1.000 109.96160 ? 213 LEU B CD1 1 
ATOM   3942 C CD2 . LEU B 1 253 ? 22.38499  -61.69646 23.26406  1.000 100.50151 ? 213 LEU B CD2 1 
ATOM   3943 N N   . PHE B 1 254 ? 24.53024  -65.49280 19.32234  1.000 113.37282 ? 214 PHE B N   1 
ATOM   3944 C CA  . PHE B 1 254 ? 25.77203  -66.24979 19.18829  1.000 114.00054 ? 214 PHE B CA  1 
ATOM   3945 C C   . PHE B 1 254 ? 25.84372  -66.99483 17.85950  1.000 119.33348 ? 214 PHE B C   1 
ATOM   3946 O O   . PHE B 1 254 ? 26.51528  -68.02534 17.76064  1.000 118.49178 ? 214 PHE B O   1 
ATOM   3947 C CB  . PHE B 1 254 ? 25.95260  -67.24078 20.34149  1.000 111.90285 ? 214 PHE B CB  1 
ATOM   3948 C CG  . PHE B 1 254 ? 25.56975  -66.69905 21.69241  1.000 111.38196 ? 214 PHE B CG  1 
ATOM   3949 C CD1 . PHE B 1 254 ? 24.24708  -66.68514 22.10969  1.000 107.72921 ? 214 PHE B CD1 1 
ATOM   3950 C CD2 . PHE B 1 254 ? 26.54359  -66.23262 22.55956  1.000 111.17894 ? 214 PHE B CD2 1 
ATOM   3951 C CE1 . PHE B 1 254 ? 23.90298  -66.19356 23.35488  1.000 109.32901 ? 214 PHE B CE1 1 
ATOM   3952 C CE2 . PHE B 1 254 ? 26.20562  -65.74313 23.80716  1.000 111.22197 ? 214 PHE B CE2 1 
ATOM   3953 C CZ  . PHE B 1 254 ? 24.88340  -65.72373 24.20493  1.000 109.12606 ? 214 PHE B CZ  1 
ATOM   3954 N N   . VAL B 1 255 ? 25.16850  -66.49605 16.82837  1.000 126.00307 ? 215 VAL B N   1 
ATOM   3955 C CA  . VAL B 1 255 ? 25.16208  -67.17970 15.53668  1.000 128.94324 ? 215 VAL B CA  1 
ATOM   3956 C C   . VAL B 1 255 ? 26.27519  -66.66467 14.63315  1.000 124.92136 ? 215 VAL B C   1 
ATOM   3957 O O   . VAL B 1 255 ? 27.00403  -67.44593 14.01590  1.000 117.97107 ? 215 VAL B O   1 
ATOM   3958 C CB  . VAL B 1 255 ? 23.77483  -67.03759 14.87076  1.000 118.34078 ? 215 VAL B CB  1 
ATOM   3959 C CG1 . VAL B 1 255 ? 23.24903  -65.61802 15.01620  1.000 115.35176 ? 215 VAL B CG1 1 
ATOM   3960 C CG2 . VAL B 1 255 ? 23.84114  -67.43355 13.40302  1.000 116.64917 ? 215 VAL B CG2 1 
ATOM   3961 N N   . HIS B 1 256 ? 26.42614  -65.34645 14.55163  1.000 125.64485 ? 216 HIS B N   1 
ATOM   3962 C CA  . HIS B 1 256 ? 27.43599  -64.70392 13.72262  1.000 124.17285 ? 216 HIS B CA  1 
ATOM   3963 C C   . HIS B 1 256 ? 28.73833  -64.43311 14.46572  1.000 124.62521 ? 216 HIS B C   1 
ATOM   3964 O O   . HIS B 1 256 ? 29.67943  -63.90696 13.86265  1.000 116.35085 ? 216 HIS B O   1 
ATOM   3965 C CB  . HIS B 1 256 ? 26.88228  -63.39423 13.15438  1.000 121.62362 ? 216 HIS B CB  1 
ATOM   3966 C CG  . HIS B 1 256 ? 25.67196  -62.88897 13.87638  1.000 129.53520 ? 216 HIS B CG  1 
ATOM   3967 N ND1 . HIS B 1 256 ? 25.69691  -62.51666 15.20340  1.000 131.54560 ? 216 HIS B ND1 1 
ATOM   3968 C CD2 . HIS B 1 256 ? 24.39789  -62.70248 13.45722  1.000 128.57264 ? 216 HIS B CD2 1 
ATOM   3969 C CE1 . HIS B 1 256 ? 24.49135  -62.11937 15.56942  1.000 131.84202 ? 216 HIS B CE1 1 
ATOM   3970 N NE2 . HIS B 1 256 ? 23.68452  -62.22277 14.52864  1.000 129.16502 ? 216 HIS B NE2 1 
ATOM   3971 N N   . ASP B 1 257 ? 28.81620  -64.77615 15.74819  1.000 128.65945 ? 217 ASP B N   1 
ATOM   3972 C CA  . ASP B 1 257 ? 29.99881  -64.54468 16.56494  1.000 118.13105 ? 217 ASP B CA  1 
ATOM   3973 C C   . ASP B 1 257 ? 30.65696  -65.86253 16.94962  1.000 107.66820 ? 217 ASP B C   1 
ATOM   3974 O O   . ASP B 1 257 ? 29.97149  -66.84884 17.23884  1.000 103.27397 ? 217 ASP B O   1 
ATOM   3975 C CB  . ASP B 1 257 ? 29.63327  -63.76386 17.83136  1.000 117.30582 ? 217 ASP B CB  1 
ATOM   3976 C CG  . ASP B 1 257 ? 28.89831  -62.47219 17.52777  1.000 114.71105 ? 217 ASP B CG  1 
ATOM   3977 O OD1 . ASP B 1 257 ? 29.33389  -61.74103 16.61443  1.000 108.72152 ? 217 ASP B OD1 1 
ATOM   3978 O OD2 . ASP B 1 257 ? 27.87561  -62.19527 18.19034  1.000 111.80954 ? 217 ASP B OD2 1 
ATOM   3979 N N   . GLU B 1 258 ? 31.98981  -65.87643 16.93186  1.000 102.37327 ? 218 GLU B N   1 
ATOM   3980 C CA  . GLU B 1 258 ? 32.73548  -67.03470 17.40781  1.000 95.07103  ? 218 GLU B CA  1 
ATOM   3981 C C   . GLU B 1 258 ? 32.37592  -67.31007 18.86031  1.000 92.33713  ? 218 GLU B C   1 
ATOM   3982 O O   . GLU B 1 258 ? 32.53032  -66.43883 19.72178  1.000 95.10426  ? 218 GLU B O   1 
ATOM   3983 C CB  . GLU B 1 258 ? 34.23548  -66.78107 17.27010  1.000 84.28078  ? 218 GLU B CB  1 
ATOM   3984 C CG  . GLU B 1 258 ? 35.11352  -67.81296 17.95961  1.000 84.61500  ? 218 GLU B CG  1 
ATOM   3985 C CD  . GLU B 1 258 ? 36.54763  -67.34138 18.10575  1.000 91.61394  ? 218 GLU B CD  1 
ATOM   3986 O OE1 . GLU B 1 258 ? 36.88683  -66.28345 17.53486  1.000 79.81496  ? 218 GLU B OE1 1 
ATOM   3987 O OE2 . GLU B 1 258 ? 37.33415  -68.02391 18.79329  1.000 89.70901  ? 218 GLU B OE2 1 
ATOM   3988 N N   . THR B 1 259 ? 31.89614  -68.52128 19.13398  1.000 98.79375  ? 219 THR B N   1 
ATOM   3989 C CA  . THR B 1 259 ? 31.36208  -68.84110 20.45023  1.000 100.91153 ? 219 THR B CA  1 
ATOM   3990 C C   . THR B 1 259 ? 31.84818  -70.20515 20.91431  1.000 97.27744  ? 219 THR B C   1 
ATOM   3991 O O   . THR B 1 259 ? 31.73878  -71.19006 20.17828  1.000 102.68466 ? 219 THR B O   1 
ATOM   3992 C CB  . THR B 1 259 ? 29.82904  -68.81126 20.44122  1.000 90.57164  ? 219 THR B CB  1 
ATOM   3993 O OG1 . THR B 1 259 ? 29.37633  -67.51768 20.02236  1.000 77.95252  ? 219 THR B OG1 1 
ATOM   3994 C CG2 . THR B 1 259 ? 29.28383  -69.10509 21.83088  1.000 88.11342  ? 219 THR B CG2 1 
ATOM   3995 N N   . HIS B 1 260 ? 32.37888  -70.25422 22.13358  1.000 91.77335  ? 220 HIS B N   1 
ATOM   3996 C CA  . HIS B 1 260 ? 32.76543  -71.49430 22.79075  1.000 86.28339  ? 220 HIS B CA  1 
ATOM   3997 C C   . HIS B 1 260 ? 31.82102  -71.75734 23.95581  1.000 93.28302  ? 220 HIS B C   1 
ATOM   3998 O O   . HIS B 1 260 ? 31.42881  -70.82859 24.66978  1.000 89.41984  ? 220 HIS B O   1 
ATOM   3999 C CB  . HIS B 1 260 ? 34.20763  -71.44422 23.30475  1.000 84.45441  ? 220 HIS B CB  1 
ATOM   4000 C CG  . HIS B 1 260 ? 35.23127  -71.24017 22.23253  1.000 91.39527  ? 220 HIS B CG  1 
ATOM   4001 N ND1 . HIS B 1 260 ? 35.72721  -69.99714 21.90307  1.000 88.03270  ? 220 HIS B ND1 1 
ATOM   4002 C CD2 . HIS B 1 260 ? 35.86007  -72.12332 21.42129  1.000 93.07129  ? 220 HIS B CD2 1 
ATOM   4003 C CE1 . HIS B 1 260 ? 36.61402  -70.12255 20.93211  1.000 72.26087  ? 220 HIS B CE1 1 
ATOM   4004 N NE2 . HIS B 1 260 ? 36.71313  -71.40248 20.62135  1.000 87.51768  ? 220 HIS B NE2 1 
ATOM   4005 N N   . VAL B 1 261 ? 31.45439  -73.02282 24.14329  1.000 98.58688  ? 221 VAL B N   1 
ATOM   4006 C CA  . VAL B 1 261 ? 30.57679  -73.44112 25.22952  1.000 90.83482  ? 221 VAL B CA  1 
ATOM   4007 C C   . VAL B 1 261 ? 31.29218  -74.51455 26.03638  1.000 85.40554  ? 221 VAL B C   1 
ATOM   4008 O O   . VAL B 1 261 ? 31.86203  -75.45188 25.46526  1.000 83.37980  ? 221 VAL B O   1 
ATOM   4009 C CB  . VAL B 1 261 ? 29.22688  -73.96378 24.70564  1.000 75.05017  ? 221 VAL B CB  1 
ATOM   4010 C CG1 . VAL B 1 261 ? 28.29162  -74.25205 25.86596  1.000 80.57508  ? 221 VAL B CG1 1 
ATOM   4011 C CG2 . VAL B 1 261 ? 28.60119  -72.96340 23.74703  1.000 79.82405  ? 221 VAL B CG2 1 
ATOM   4012 N N   . LEU B 1 262 ? 31.26120  -74.37454 27.36019  1.000 83.77336  ? 222 LEU B N   1 
ATOM   4013 C CA  . LEU B 1 262 ? 31.85164  -75.33917 28.27567  1.000 74.80185  ? 222 LEU B CA  1 
ATOM   4014 C C   . LEU B 1 262 ? 30.86774  -75.61945 29.39950  1.000 86.56556  ? 222 LEU B C   1 
ATOM   4015 O O   . LEU B 1 262 ? 30.18946  -74.70757 29.88146  1.000 78.80832  ? 222 LEU B O   1 
ATOM   4016 C CB  . LEU B 1 262 ? 33.17920  -74.83240 28.87165  1.000 83.39402  ? 222 LEU B CB  1 
ATOM   4017 C CG  . LEU B 1 262 ? 34.48071  -74.91420 28.06470  1.000 89.41017  ? 222 LEU B CG  1 
ATOM   4018 C CD1 . LEU B 1 262 ? 34.50096  -73.93573 26.90108  1.000 93.41359  ? 222 LEU B CD1 1 
ATOM   4019 C CD2 . LEU B 1 262 ? 35.68674  -74.68882 28.96765  1.000 89.93475  ? 222 LEU B CD2 1 
ATOM   4020 N N   . GLN B 1 263 ? 30.79137  -76.88117 29.81302  1.000 92.70942  ? 223 GLN B N   1 
ATOM   4021 C CA  . GLN B 1 263 ? 29.94243  -77.26999 30.92869  1.000 85.62178  ? 223 GLN B CA  1 
ATOM   4022 C C   . GLN B 1 263 ? 30.73844  -77.24119 32.22494  1.000 78.58120  ? 223 GLN B C   1 
ATOM   4023 O O   . GLN B 1 263 ? 31.87922  -77.70909 32.28036  1.000 69.12414  ? 223 GLN B O   1 
ATOM   4024 C CB  . GLN B 1 263 ? 29.35572  -78.66573 30.71885  1.000 91.71152  ? 223 GLN B CB  1 
ATOM   4025 C CG  . GLN B 1 263 ? 28.27593  -79.01845 31.73200  1.000 104.36930 ? 223 GLN B CG  1 
ATOM   4026 C CD  . GLN B 1 263 ? 27.85043  -80.47029 31.65997  1.000 100.22155 ? 223 GLN B CD  1 
ATOM   4027 O OE1 . GLN B 1 263 ? 26.66612  -80.78822 31.76243  1.000 91.84929  ? 223 GLN B OE1 1 
ATOM   4028 N NE2 . GLN B 1 263 ? 28.82008  -81.36277 31.50205  1.000 88.62578  ? 223 GLN B NE2 1 
ATOM   4029 N N   . VAL B 1 264 ? 30.12693  -76.68520 33.27033  1.000 71.86646  ? 224 VAL B N   1 
ATOM   4030 C CA  . VAL B 1 264 ? 30.75998  -76.56380 34.57576  1.000 81.48557  ? 224 VAL B CA  1 
ATOM   4031 C C   . VAL B 1 264 ? 29.76667  -76.99341 35.64579  1.000 75.55734  ? 224 VAL B C   1 
ATOM   4032 O O   . VAL B 1 264 ? 28.55045  -76.99004 35.44110  1.000 71.85181  ? 224 VAL B O   1 
ATOM   4033 C CB  . VAL B 1 264 ? 31.26448  -75.12987 34.86474  1.000 83.36937  ? 224 VAL B CB  1 
ATOM   4034 C CG1 . VAL B 1 264 ? 32.30871  -74.70766 33.84221  1.000 64.33533  ? 224 VAL B CG1 1 
ATOM   4035 C CG2 . VAL B 1 264 ? 30.10415  -74.15303 34.87464  1.000 70.98040  ? 224 VAL B CG2 1 
ATOM   4036 N N   . ASP B 1 265 ? 30.30982  -77.36603 36.80571  1.000 74.82252  ? 225 ASP B N   1 
ATOM   4037 C CA  . ASP B 1 265 ? 29.46415  -77.79518 37.91334  1.000 72.63028  ? 225 ASP B CA  1 
ATOM   4038 C C   . ASP B 1 265 ? 28.77012  -76.60879 38.56926  1.000 78.79831  ? 225 ASP B C   1 
ATOM   4039 O O   . ASP B 1 265 ? 27.57986  -76.68206 38.89465  1.000 71.51655  ? 225 ASP B O   1 
ATOM   4040 C CB  . ASP B 1 265 ? 30.29503  -78.56025 38.94292  1.000 81.88420  ? 225 ASP B CB  1 
ATOM   4041 C CG  . ASP B 1 265 ? 30.92465  -79.81292 38.37080  1.000 98.71799  ? 225 ASP B CG  1 
ATOM   4042 O OD1 . ASP B 1 265 ? 30.30118  -80.44888 37.49549  1.000 96.19561  ? 225 ASP B OD1 1 
ATOM   4043 O OD2 . ASP B 1 265 ? 32.04439  -80.16105 38.79871  1.000 97.74723  ? 225 ASP B OD2 1 
ATOM   4044 N N   . ASP B 1 266 ? 29.49768  -75.51247 38.77876  1.000 80.59030  ? 226 ASP B N   1 
ATOM   4045 C CA  . ASP B 1 266 ? 28.97308  -74.34488 39.48166  1.000 73.48917  ? 226 ASP B CA  1 
ATOM   4046 C C   . ASP B 1 266 ? 29.45640  -73.09263 38.76190  1.000 78.45015  ? 226 ASP B C   1 
ATOM   4047 O O   . ASP B 1 266 ? 30.63338  -72.73341 38.86610  1.000 77.38421  ? 226 ASP B O   1 
ATOM   4048 C CB  . ASP B 1 266 ? 29.42138  -74.34432 40.94363  1.000 73.13420  ? 226 ASP B CB  1 
ATOM   4049 C CG  . ASP B 1 266 ? 28.65915  -73.34618 41.78944  1.000 79.03298  ? 226 ASP B CG  1 
ATOM   4050 O OD1 . ASP B 1 266 ? 27.76158  -72.66543 41.25064  1.000 75.74838  ? 226 ASP B OD1 1 
ATOM   4051 O OD2 . ASP B 1 266 ? 28.96022  -73.24385 42.99737  1.000 79.99694  ? 226 ASP B OD2 1 
ATOM   4052 N N   . VAL B 1 267 ? 28.55472  -72.43003 38.03086  1.000 80.30191  ? 227 VAL B N   1 
ATOM   4053 C CA  . VAL B 1 267 ? 28.92585  -71.18985 37.35280  1.000 72.35859  ? 227 VAL B CA  1 
ATOM   4054 C C   . VAL B 1 267 ? 29.19569  -70.08907 38.36961  1.000 71.94699  ? 227 VAL B C   1 
ATOM   4055 O O   . VAL B 1 267 ? 29.95066  -69.14948 38.09296  1.000 70.36148  ? 227 VAL B O   1 
ATOM   4056 C CB  . VAL B 1 267 ? 27.84484  -70.76532 36.33853  1.000 75.09285  ? 227 VAL B CB  1 
ATOM   4057 C CG1 . VAL B 1 267 ? 27.40266  -71.94987 35.49434  1.000 79.54085  ? 227 VAL B CG1 1 
ATOM   4058 C CG2 . VAL B 1 267 ? 26.65879  -70.11960 37.04047  1.000 74.54925  ? 227 VAL B CG2 1 
ATOM   4059 N N   . LYS B 1 268 ? 28.58410  -70.18153 39.55395  1.000 65.83473  ? 228 LYS B N   1 
ATOM   4060 C CA  . LYS B 1 268 ? 28.78681  -69.17650 40.59189  1.000 63.79171  ? 228 LYS B CA  1 
ATOM   4061 C C   . LYS B 1 268 ? 30.24423  -69.09666 41.02506  1.000 69.58501  ? 228 LYS B C   1 
ATOM   4062 O O   . LYS B 1 268 ? 30.70482  -68.03643 41.46335  1.000 65.17670  ? 228 LYS B O   1 
ATOM   4063 C CB  . LYS B 1 268 ? 27.88881  -69.49235 41.78991  1.000 62.93976  ? 228 LYS B CB  1 
ATOM   4064 C CG  . LYS B 1 268 ? 27.81260  -68.40513 42.84761  1.000 84.55284  ? 228 LYS B CG  1 
ATOM   4065 C CD  . LYS B 1 268 ? 28.70786  -68.74595 44.03458  1.000 90.77722  ? 228 LYS B CD  1 
ATOM   4066 C CE  . LYS B 1 268 ? 28.55560  -67.74032 45.16409  1.000 88.55846  ? 228 LYS B CE  1 
ATOM   4067 N NZ  . LYS B 1 268 ? 29.25925  -68.19217 46.39788  1.000 94.42108  ? 228 LYS B NZ  1 
ATOM   4068 N N   . GLN B 1 269 ? 30.98291  -70.20061 40.91617  1.000 64.13783  ? 229 GLN B N   1 
ATOM   4069 C CA  . GLN B 1 269 ? 32.39372  -70.20752 41.27998  1.000 54.35822  ? 229 GLN B CA  1 
ATOM   4070 C C   . GLN B 1 269 ? 33.25688  -69.40094 40.31636  1.000 56.60153  ? 229 GLN B C   1 
ATOM   4071 O O   . GLN B 1 269 ? 34.42919  -69.15123 40.61811  1.000 56.49386  ? 229 GLN B O   1 
ATOM   4072 C CB  . GLN B 1 269 ? 32.90279  -71.64711 41.35185  1.000 59.31110  ? 229 GLN B CB  1 
ATOM   4073 C CG  . GLN B 1 269 ? 33.94621  -71.86207 42.42723  1.000 74.27568  ? 229 GLN B CG  1 
ATOM   4074 C CD  . GLN B 1 269 ? 33.39363  -71.59503 43.81457  1.000 78.08203  ? 229 GLN B CD  1 
ATOM   4075 O OE1 . GLN B 1 269 ? 32.20099  -71.77487 44.06631  1.000 57.68970  ? 229 GLN B OE1 1 
ATOM   4076 N NE2 . GLN B 1 269 ? 34.25886  -71.16425 44.72284  1.000 74.61517  ? 229 GLN B NE2 1 
ATOM   4077 N N   . LEU B 1 270 ? 32.71194  -68.99800 39.17219  1.000 51.39361  ? 230 LEU B N   1 
ATOM   4078 C CA  . LEU B 1 270 ? 33.45262  -68.29123 38.13712  1.000 48.11356  ? 230 LEU B CA  1 
ATOM   4079 C C   . LEU B 1 270 ? 33.12377  -66.80555 38.08224  1.000 59.29561  ? 230 LEU B C   1 
ATOM   4080 O O   . LEU B 1 270 ? 33.70182  -66.08710 37.26143  1.000 58.83700  ? 230 LEU B O   1 
ATOM   4081 C CB  . LEU B 1 270 ? 33.19152  -68.92307 36.76157  1.000 50.28402  ? 230 LEU B CB  1 
ATOM   4082 C CG  . LEU B 1 270 ? 33.70562  -70.32574 36.41162  1.000 54.56833  ? 230 LEU B CG  1 
ATOM   4083 C CD1 . LEU B 1 270 ? 33.08634  -71.43609 37.25720  1.000 70.73149  ? 230 LEU B CD1 1 
ATOM   4084 C CD2 . LEU B 1 270 ? 33.47981  -70.60103 34.93009  1.000 48.54093  ? 230 LEU B CD2 1 
ATOM   4085 N N   . ILE B 1 271 ? 32.20877  -66.33249 38.92114  1.000 53.72972  ? 231 ILE B N   1 
ATOM   4086 C CA  . ILE B 1 271 ? 31.65450  -64.99133 38.77819  1.000 57.89179  ? 231 ILE B CA  1 
ATOM   4087 C C   . ILE B 1 271 ? 32.63012  -63.97236 39.35219  1.000 58.95443  ? 231 ILE B C   1 
ATOM   4088 O O   . ILE B 1 271 ? 33.08578  -64.10387 40.49493  1.000 57.59547  ? 231 ILE B O   1 
ATOM   4089 C CB  . ILE B 1 271 ? 30.29052  -64.89370 39.48098  1.000 60.43722  ? 231 ILE B CB  1 
ATOM   4090 C CG1 . ILE B 1 271 ? 29.26275  -65.80073 38.80203  1.000 64.16974  ? 231 ILE B CG1 1 
ATOM   4091 C CG2 . ILE B 1 271 ? 29.79821  -63.45199 39.49168  1.000 50.03055  ? 231 ILE B CG2 1 
ATOM   4092 C CD1 . ILE B 1 271 ? 28.98220  -65.43892 37.37431  1.000 72.18490  ? 231 ILE B CD1 1 
ATOM   4093 N N   . ASP B 1 272 ? 32.95793  -62.95583 38.55507  1.000 53.05722  ? 232 ASP B N   1 
ATOM   4094 C CA  . ASP B 1 272 ? 33.65175  -61.77306 39.04876  1.000 53.70322  ? 232 ASP B CA  1 
ATOM   4095 C C   . ASP B 1 272 ? 33.14433  -60.58245 38.25118  1.000 52.80749  ? 232 ASP B C   1 
ATOM   4096 O O   . ASP B 1 272 ? 33.09962  -60.63402 37.01777  1.000 57.58704  ? 232 ASP B O   1 
ATOM   4097 C CB  . ASP B 1 272 ? 35.17388  -61.90003 38.92607  1.000 55.21961  ? 232 ASP B CB  1 
ATOM   4098 C CG  . ASP B 1 272 ? 35.88687  -60.58277 39.17083  1.000 59.35711  ? 232 ASP B CG  1 
ATOM   4099 O OD1 . ASP B 1 272 ? 36.01065  -60.18220 40.34792  1.000 51.95961  ? 232 ASP B OD1 1 
ATOM   4100 O OD2 . ASP B 1 272 ? 36.31323  -59.94271 38.18855  1.000 57.01966  ? 232 ASP B OD2 1 
ATOM   4101 N N   A ARG B 1 273 ? 32.76579  -59.51735 38.95794  0.527 46.91305  ? 233 ARG B N   1 
ATOM   4102 N N   B ARG B 1 273 ? 32.76164  -59.51813 38.95301  0.473 47.80054  ? 233 ARG B N   1 
ATOM   4103 C CA  A ARG B 1 273 ? 32.14653  -58.34843 38.35057  0.527 53.97536  ? 233 ARG B CA  1 
ATOM   4104 C CA  B ARG B 1 273 ? 32.14172  -58.36327 38.32298  0.473 53.79651  ? 233 ARG B CA  1 
ATOM   4105 C C   A ARG B 1 273 ? 33.16081  -57.29868 37.91246  0.527 53.28086  ? 233 ARG B C   1 
ATOM   4106 C C   B ARG B 1 273 ? 33.15521  -57.30168 37.90974  0.473 54.60907  ? 233 ARG B C   1 
ATOM   4107 O O   A ARG B 1 273 ? 32.77892  -56.15260 37.64927  0.527 47.68287  ? 233 ARG B O   1 
ATOM   4108 O O   B ARG B 1 273 ? 32.77038  -56.15388 37.65824  0.473 47.96705  ? 233 ARG B O   1 
ATOM   4109 C CB  A ARG B 1 273 ? 31.12838  -57.73818 39.31531  0.527 46.50321  ? 233 ARG B CB  1 
ATOM   4110 C CB  B ARG B 1 273 ? 31.08005  -57.77307 39.25275  0.473 46.41840  ? 233 ARG B CB  1 
ATOM   4111 C CG  A ARG B 1 273 ? 29.90567  -58.61368 39.51788  0.527 49.67990  ? 233 ARG B CG  1 
ATOM   4112 C CG  B ARG B 1 273 ? 30.12850  -58.82992 39.79338  0.473 50.22963  ? 233 ARG B CG  1 
ATOM   4113 C CD  A ARG B 1 273 ? 29.14141  -58.24224 40.77211  0.527 58.08127  ? 233 ARG B CD  1 
ATOM   4114 C CD  B ARG B 1 273 ? 28.82285  -58.24206 40.29282  0.473 57.58828  ? 233 ARG B CD  1 
ATOM   4115 N NE  A ARG B 1 273 ? 28.05092  -59.17660 41.02316  0.527 60.32735  ? 233 ARG B NE  1 
ATOM   4116 N NE  B ARG B 1 273 ? 27.98240  -59.26656 40.90215  0.473 60.37803  ? 233 ARG B NE  1 
ATOM   4117 C CZ  A ARG B 1 273 ? 28.19350  -60.35236 41.62019  0.527 58.61549  ? 233 ARG B CZ  1 
ATOM   4118 C CZ  B ARG B 1 273 ? 27.08345  -59.99112 40.24944  0.473 61.47694  ? 233 ARG B CZ  1 
ATOM   4119 N NH1 A ARG B 1 273 ? 29.37244  -60.77126 42.05146  0.527 40.02880  ? 233 ARG B NH1 1 
ATOM   4120 N NH1 B ARG B 1 273 ? 26.85400  -59.81078 38.95922  0.473 56.63808  ? 233 ARG B NH1 1 
ATOM   4121 N NH2 A ARG B 1 273 ? 27.12664  -61.12888 41.78627  0.527 66.09020  ? 233 ARG B NH2 1 
ATOM   4122 N NH2 B ARG B 1 273 ? 26.39094  -60.91445 40.91060  0.473 62.56517  ? 233 ARG B NH2 1 
ATOM   4123 N N   . GLY B 1 274 ? 34.43848  -57.66025 37.82893  1.000 48.20787  ? 234 GLY B N   1 
ATOM   4124 C CA  . GLY B 1 274 ? 35.41350  -56.76787 37.24983  1.000 49.19159  ? 234 GLY B CA  1 
ATOM   4125 C C   . GLY B 1 274 ? 35.46213  -56.91293 35.74123  1.000 49.95068  ? 234 GLY B C   1 
ATOM   4126 O O   . GLY B 1 274 ? 35.09455  -57.94367 35.17937  1.000 57.72383  ? 234 GLY B O   1 
ATOM   4127 N N   . ILE B 1 275 ? 35.92100  -55.85894 35.06601  1.000 51.72293  ? 235 ILE B N   1 
ATOM   4128 C CA  . ILE B 1 275 ? 35.98886  -55.85751 33.60995  1.000 54.84419  ? 235 ILE B CA  1 
ATOM   4129 C C   . ILE B 1 275 ? 37.07732  -54.89108 33.16644  1.000 50.66989  ? 235 ILE B C   1 
ATOM   4130 O O   . ILE B 1 275 ? 37.53369  -54.03882 33.93178  1.000 55.13186  ? 235 ILE B O   1 
ATOM   4131 C CB  . ILE B 1 275 ? 34.62591  -55.48064 32.97792  1.000 48.11685  ? 235 ILE B CB  1 
ATOM   4132 C CG1 . ILE B 1 275 ? 34.56038  -55.92649 31.51602  1.000 45.59815  ? 235 ILE B CG1 1 
ATOM   4133 C CG2 . ILE B 1 275 ? 34.38793  -53.98678 33.08988  1.000 43.78131  ? 235 ILE B CG2 1 
ATOM   4134 C CD1 . ILE B 1 275 ? 33.18003  -55.84633 30.92137  1.000 53.24590  ? 235 ILE B CD1 1 
ATOM   4135 N N   . ALA B 1 276 ? 37.49518  -55.03432 31.91142  1.000 48.04520  ? 236 ALA B N   1 
ATOM   4136 C CA  . ALA B 1 276 ? 38.46835  -54.15313 31.29129  1.000 47.63956  ? 236 ALA B CA  1 
ATOM   4137 C C   . ALA B 1 276 ? 37.88872  -53.56113 30.01386  1.000 48.96012  ? 236 ALA B C   1 
ATOM   4138 O O   . ALA B 1 276 ? 37.09729  -54.19981 29.31504  1.000 53.01314  ? 236 ALA B O   1 
ATOM   4139 C CB  . ALA B 1 276 ? 39.77600  -54.89516 30.97805  1.000 46.73047  ? 236 ALA B CB  1 
ATOM   4140 N N   . VAL B 1 277 ? 38.28152  -52.32295 29.72667  1.000 44.47944  ? 237 VAL B N   1 
ATOM   4141 C CA  . VAL B 1 277 ? 37.95203  -51.64161 28.48072  1.000 46.99101  ? 237 VAL B CA  1 
ATOM   4142 C C   . VAL B 1 277 ? 39.22451  -51.00065 27.95624  1.000 48.08174  ? 237 VAL B C   1 
ATOM   4143 O O   . VAL B 1 277 ? 39.87477  -50.23438 28.67498  1.000 56.03204  ? 237 VAL B O   1 
ATOM   4144 C CB  . VAL B 1 277 ? 36.86048  -50.57208 28.67637  1.000 50.24183  ? 237 VAL B CB  1 
ATOM   4145 C CG1 . VAL B 1 277 ? 36.63564  -49.80210 27.38354  1.000 47.65285  ? 237 VAL B CG1 1 
ATOM   4146 C CG2 . VAL B 1 277 ? 35.56930  -51.20644 29.15124  1.000 44.75131  ? 237 VAL B CG2 1 
ATOM   4147 N N   . ARG B 1 278 ? 39.58987  -51.31489 26.71667  1.000 45.42918  ? 238 ARG B N   1 
ATOM   4148 C CA  . ARG B 1 278 ? 40.77436  -50.72302 26.11229  1.000 57.35925  ? 238 ARG B CA  1 
ATOM   4149 C C   . ARG B 1 278 ? 40.37655  -50.10446 24.78003  1.000 57.99187  ? 238 ARG B C   1 
ATOM   4150 O O   . ARG B 1 278 ? 39.82150  -50.79180 23.91644  1.000 46.07729  ? 238 ARG B O   1 
ATOM   4151 C CB  . ARG B 1 278 ? 41.88405  -51.76421 25.94329  1.000 55.92806  ? 238 ARG B CB  1 
ATOM   4152 C CG  . ARG B 1 278 ? 43.23862  -51.15810 25.64658  1.000 69.41269  ? 238 ARG B CG  1 
ATOM   4153 C CD  . ARG B 1 278 ? 44.33462  -52.20785 25.69030  1.000 79.96415  ? 238 ARG B CD  1 
ATOM   4154 N NE  . ARG B 1 278 ? 45.65328  -51.59641 25.57084  1.000 77.40549  ? 238 ARG B NE  1 
ATOM   4155 C CZ  . ARG B 1 278 ? 46.29139  -51.37099 24.43192  1.000 79.90752  ? 238 ARG B CZ  1 
ATOM   4156 N NH1 . ARG B 1 278 ? 45.76718  -51.70920 23.26708  1.000 83.39312  ? 238 ARG B NH1 1 
ATOM   4157 N NH2 . ARG B 1 278 ? 47.48634  -50.78793 24.46421  1.000 70.20580  ? 238 ARG B NH2 1 
ATOM   4158 N N   . MET B 1 279 ? 40.64678  -48.81092 24.62057  1.000 50.27108  ? 239 MET B N   1 
ATOM   4159 C CA  . MET B 1 279 ? 40.32315  -48.07367 23.40631  1.000 56.92176  ? 239 MET B CA  1 
ATOM   4160 C C   . MET B 1 279 ? 41.61053  -47.62635 22.73040  1.000 49.29466  ? 239 MET B C   1 
ATOM   4161 O O   . MET B 1 279 ? 42.50120  -47.07074 23.38250  1.000 53.47445  ? 239 MET B O   1 
ATOM   4162 C CB  . MET B 1 279 ? 39.44274  -46.85791 23.71000  1.000 55.23587  ? 239 MET B CB  1 
ATOM   4163 C CG  . MET B 1 279 ? 37.95459  -47.08911 23.50281  1.000 59.17776  ? 239 MET B CG  1 
ATOM   4164 S SD  . MET B 1 279 ? 36.93946  -45.73197 24.12318  1.000 69.93796  ? 239 MET B SD  1 
ATOM   4165 C CE  . MET B 1 279 ? 37.04195  -46.00280 25.89170  1.000 62.82675  ? 239 MET B CE  1 
ATOM   4166 N N   . GLU B 1 280 ? 41.70520  -47.87528 21.42788  1.000 50.15718  ? 240 GLU B N   1 
ATOM   4167 C CA  . GLU B 1 280 ? 42.84834  -47.47050 20.62537  1.000 47.61231  ? 240 GLU B CA  1 
ATOM   4168 C C   . GLU B 1 280 ? 42.34943  -46.64772 19.44925  1.000 49.09290  ? 240 GLU B C   1 
ATOM   4169 O O   . GLU B 1 280 ? 41.31601  -46.96977 18.85404  1.000 47.91326  ? 240 GLU B O   1 
ATOM   4170 C CB  . GLU B 1 280 ? 43.62636  -48.68737 20.11084  1.000 47.81431  ? 240 GLU B CB  1 
ATOM   4171 C CG  . GLU B 1 280 ? 43.94852  -49.71837 21.17735  1.000 66.25708  ? 240 GLU B CG  1 
ATOM   4172 C CD  . GLU B 1 280 ? 44.42146  -51.02936 20.58265  1.000 87.95812  ? 240 GLU B CD  1 
ATOM   4173 O OE1 . GLU B 1 280 ? 44.64520  -51.08060 19.35520  1.000 84.15866  ? 240 GLU B OE1 1 
ATOM   4174 O OE2 . GLU B 1 280 ? 44.56188  -52.01077 21.34083  1.000 96.56213  ? 240 GLU B OE2 1 
ATOM   4175 N N   . ARG B 1 281 ? 43.07725  -45.58280 19.11990  1.000 48.44517  ? 241 ARG B N   1 
ATOM   4176 C CA  . ARG B 1 281 ? 42.83164  -44.84910 17.88651  1.000 44.09446  ? 241 ARG B CA  1 
ATOM   4177 C C   . ARG B 1 281 ? 44.15402  -44.48203 17.23529  1.000 42.65133  ? 241 ARG B C   1 
ATOM   4178 O O   . ARG B 1 281 ? 45.05355  -43.95550 17.89731  1.000 44.77282  ? 241 ARG B O   1 
ATOM   4179 C CB  . ARG B 1 281 ? 42.00551  -43.58026 18.13545  1.000 49.53219  ? 241 ARG B CB  1 
ATOM   4180 C CG  . ARG B 1 281 ? 41.74197  -42.78521 16.86531  1.000 44.84052  ? 241 ARG B CG  1 
ATOM   4181 C CD  . ARG B 1 281 ? 40.73237  -41.67387 17.07961  1.000 45.05086  ? 241 ARG B CD  1 
ATOM   4182 N NE  . ARG B 1 281 ? 40.33033  -41.07371 15.81300  1.000 55.40372  ? 241 ARG B NE  1 
ATOM   4183 C CZ  . ARG B 1 281 ? 39.43241  -41.59722 14.98925  1.000 47.80362  ? 241 ARG B CZ  1 
ATOM   4184 N NH1 . ARG B 1 281 ? 38.81509  -42.73249 15.27139  1.000 50.60350  ? 241 ARG B NH1 1 
ATOM   4185 N NH2 . ARG B 1 281 ? 39.14536  -40.96520 13.85477  1.000 46.13493  ? 241 ARG B NH2 1 
ATOM   4186 N N   . LYS B 1 282 ? 44.26159  -44.76054 15.94045  1.000 37.42059  ? 242 LYS B N   1 
ATOM   4187 C CA  . LYS B 1 282 ? 45.35620  -44.27981 15.11153  1.000 45.75317  ? 242 LYS B CA  1 
ATOM   4188 C C   . LYS B 1 282 ? 44.74483  -43.36710 14.06220  1.000 56.14498  ? 242 LYS B C   1 
ATOM   4189 O O   . LYS B 1 282 ? 43.90456  -43.80726 13.26945  1.000 52.07603  ? 242 LYS B O   1 
ATOM   4190 C CB  . LYS B 1 282 ? 46.11613  -45.43455 14.45633  1.000 40.96072  ? 242 LYS B CB  1 
ATOM   4191 C CG  . LYS B 1 282 ? 47.29879  -44.98640 13.61382  1.000 53.68195  ? 242 LYS B CG  1 
ATOM   4192 C CD  . LYS B 1 282 ? 48.08040  -46.16947 13.06693  1.000 42.16428  ? 242 LYS B CD  1 
ATOM   4193 C CE  . LYS B 1 282 ? 47.24979  -46.98434 12.08827  1.000 41.51867  ? 242 LYS B CE  1 
ATOM   4194 N NZ  . LYS B 1 282 ? 46.79204  -46.17546 10.92283  1.000 54.52416  ? 242 LYS B NZ  1 
ATOM   4195 N N   . GLY B 1 283 ? 45.15839  -42.10375 14.05400  1.000 56.86717  ? 243 GLY B N   1 
ATOM   4196 C CA  . GLY B 1 283 ? 44.46890  -41.15209 13.21077  1.000 47.75152  ? 243 GLY B CA  1 
ATOM   4197 C C   . GLY B 1 283 ? 45.27070  -39.96540 12.72468  1.000 51.47881  ? 243 GLY B C   1 
ATOM   4198 O O   . GLY B 1 283 ? 46.47882  -39.86873 12.96055  1.000 47.63085  ? 243 GLY B O   1 
ATOM   4199 N N   . VAL B 1 284 ? 44.58695  -39.05554 12.03517  1.000 53.24447  ? 244 VAL B N   1 
ATOM   4200 C CA  . VAL B 1 284 ? 45.19658  -37.89619 11.39679  1.000 43.33731  ? 244 VAL B CA  1 
ATOM   4201 C C   . VAL B 1 284 ? 44.74938  -36.64778 12.14295  1.000 44.01692  ? 244 VAL B C   1 
ATOM   4202 O O   . VAL B 1 284 ? 43.54726  -36.37184 12.23757  1.000 52.30797  ? 244 VAL B O   1 
ATOM   4203 C CB  . VAL B 1 284 ? 44.81606  -37.80619 9.91028   1.000 48.17337  ? 244 VAL B CB  1 
ATOM   4204 C CG1 . VAL B 1 284 ? 45.50600  -36.62085 9.26467   1.000 50.89630  ? 244 VAL B CG1 1 
ATOM   4205 C CG2 . VAL B 1 284 ? 45.15921  -39.10096 9.18472   1.000 49.61800  ? 244 VAL B CG2 1 
ATOM   4206 N N   . SER B 1 285 ? 45.71039  -35.88493 12.65897  1.000 53.67714  ? 245 SER B N   1 
ATOM   4207 C CA  . SER B 1 285 ? 45.43269  -34.58125 13.24696  1.000 44.91580  ? 245 SER B CA  1 
ATOM   4208 C C   . SER B 1 285 ? 45.72588  -33.53382 12.18160  1.000 51.23752  ? 245 SER B C   1 
ATOM   4209 O O   . SER B 1 285 ? 46.89146  -33.23749 11.89467  1.000 55.68373  ? 245 SER B O   1 
ATOM   4210 C CB  . SER B 1 285 ? 46.27161  -34.34447 14.49781  1.000 42.14058  ? 245 SER B CB  1 
ATOM   4211 O OG  . SER B 1 285 ? 45.92610  -35.24652 15.53356  1.000 55.97007  ? 245 SER B OG  1 
ATOM   4212 N N   . GLY B 1 286 ? 44.66838  -32.97482 11.59784  1.000 48.97429  ? 246 GLY B N   1 
ATOM   4213 C CA  . GLY B 1 286 ? 44.83595  -32.04504 10.49765  1.000 45.30130  ? 246 GLY B CA  1 
ATOM   4214 C C   . GLY B 1 286 ? 45.20281  -32.78683 9.22752   1.000 53.31539  ? 246 GLY B C   1 
ATOM   4215 O O   . GLY B 1 286 ? 44.33883  -33.33125 8.53498   1.000 59.13346  ? 246 GLY B O   1 
ATOM   4216 N N   . GLN B 1 287 ? 46.49943  -32.80889 8.91640   1.000 57.30799  ? 247 GLN B N   1 
ATOM   4217 C CA  . GLN B 1 287 ? 47.03804  -33.58634 7.80747   1.000 52.01786  ? 247 GLN B CA  1 
ATOM   4218 C C   . GLN B 1 287 ? 48.20218  -34.46415 8.25063   1.000 42.25845  ? 247 GLN B C   1 
ATOM   4219 O O   . GLN B 1 287 ? 48.81781  -35.13203 7.41025   1.000 41.14970  ? 247 GLN B O   1 
ATOM   4220 C CB  . GLN B 1 287 ? 47.48110  -32.66389 6.66242   1.000 53.33302  ? 247 GLN B CB  1 
ATOM   4221 C CG  . GLN B 1 287 ? 46.36995  -32.29616 5.69490   1.000 60.68741  ? 247 GLN B CG  1 
ATOM   4222 C CD  . GLN B 1 287 ? 46.70362  -31.08533 4.84336   1.000 59.79921  ? 247 GLN B CD  1 
ATOM   4223 O OE1 . GLN B 1 287 ? 47.86428  -30.68489 4.73166   1.000 73.36876  ? 247 GLN B OE1 1 
ATOM   4224 N NE2 . GLN B 1 287 ? 45.68020  -30.48257 4.25467   1.000 55.02328  ? 247 GLN B NE2 1 
ATOM   4225 N N   . THR B 1 288 ? 48.50878  -34.48318 9.54568   1.000 43.70067  ? 248 THR B N   1 
ATOM   4226 C CA  . THR B 1 288 ? 49.62905  -35.24371 10.08641  1.000 48.81503  ? 248 THR B CA  1 
ATOM   4227 C C   . THR B 1 288 ? 49.16171  -36.64792 10.45039  1.000 43.77504  ? 248 THR B C   1 
ATOM   4228 O O   . THR B 1 288 ? 48.27014  -36.80948 11.29072  1.000 43.86650  ? 248 THR B O   1 
ATOM   4229 C CB  . THR B 1 288 ? 50.21221  -34.54458 11.31484  1.000 49.58379  ? 248 THR B CB  1 
ATOM   4230 O OG1 . THR B 1 288 ? 50.58262  -33.20090 10.97480  1.000 51.25111  ? 248 THR B OG1 1 
ATOM   4231 C CG2 . THR B 1 288 ? 51.43191  -35.29092 11.83114  1.000 33.13184  ? 248 THR B CG2 1 
ATOM   4232 N N   . GLN B 1 289 ? 49.76478  -37.65575 9.82196   1.000 44.21143  ? 249 GLN B N   1 
ATOM   4233 C CA  . GLN B 1 289 ? 49.37290  -39.04140 10.02471  1.000 42.86410  ? 249 GLN B CA  1 
ATOM   4234 C C   . GLN B 1 289 ? 49.92077  -39.58989 11.34431  1.000 49.15049  ? 249 GLN B C   1 
ATOM   4235 O O   . GLN B 1 289 ? 50.76000  -38.97814 12.01084  1.000 45.66112  ? 249 GLN B O   1 
ATOM   4236 C CB  . GLN B 1 289 ? 49.85982  -39.90877 8.86328   1.000 50.12846  ? 249 GLN B CB  1 
ATOM   4237 C CG  . GLN B 1 289 ? 49.72523  -39.25946 7.49497   1.000 53.21051  ? 249 GLN B CG  1 
ATOM   4238 C CD  . GLN B 1 289 ? 48.28146  -39.09926 7.05884   1.000 52.26380  ? 249 GLN B CD  1 
ATOM   4239 O OE1 . GLN B 1 289 ? 47.60393  -40.07668 6.73751   1.000 52.89736  ? 249 GLN B OE1 1 
ATOM   4240 N NE2 . GLN B 1 289 ? 47.80469  -37.86228 7.04122   1.000 41.72664  ? 249 GLN B NE2 1 
ATOM   4241 N N   . ASN B 1 290 ? 49.42028  -40.77328 11.71455  1.000 49.75179  ? 250 ASN B N   1 
ATOM   4242 C CA  . ASN B 1 290 ? 50.02593  -41.62742 12.74316  1.000 50.53304  ? 250 ASN B CA  1 
ATOM   4243 C C   . ASN B 1 290 ? 49.97029  -41.00130 14.13905  1.000 47.66203  ? 250 ASN B C   1 
ATOM   4244 O O   . ASN B 1 290 ? 50.92571  -41.09852 14.91155  1.000 53.47853  ? 250 ASN B O   1 
ATOM   4245 C CB  . ASN B 1 290 ? 51.46780  -41.99782 12.37627  1.000 42.90723  ? 250 ASN B CB  1 
ATOM   4246 C CG  . ASN B 1 290 ? 51.96600  -43.22892 13.12043  1.000 51.84651  ? 250 ASN B CG  1 
ATOM   4247 O OD1 . ASN B 1 290 ? 51.23171  -44.20203 13.29534  1.000 62.08624  ? 250 ASN B OD1 1 
ATOM   4248 N ND2 . ASN B 1 290 ? 53.21832  -43.18789 13.56443  1.000 47.27432  ? 250 ASN B ND2 1 
ATOM   4249 N N   . GLN B 1 291 ? 48.85646  -40.35097 14.46815  1.000 52.54157  ? 251 GLN B N   1 
ATOM   4250 C CA  . GLN B 1 291 ? 48.62632  -39.91752 15.83982  1.000 50.67802  ? 251 GLN B CA  1 
ATOM   4251 C C   . GLN B 1 291 ? 48.04701  -41.07934 16.63857  1.000 54.17675  ? 251 GLN B C   1 
ATOM   4252 O O   . GLN B 1 291 ? 47.05044  -41.68511 16.23357  1.000 52.50060  ? 251 GLN B O   1 
ATOM   4253 C CB  . GLN B 1 291 ? 47.68529  -38.71522 15.87457  1.000 42.95717  ? 251 GLN B CB  1 
ATOM   4254 C CG  . GLN B 1 291 ? 48.14995  -37.54161 15.02253  1.000 47.10872  ? 251 GLN B CG  1 
ATOM   4255 C CD  . GLN B 1 291 ? 49.36051  -36.82581 15.59497  1.000 50.47972  ? 251 GLN B CD  1 
ATOM   4256 O OE1 . GLN B 1 291 ? 50.49898  -37.25650 15.40543  1.000 56.28110  ? 251 GLN B OE1 1 
ATOM   4257 N NE2 . GLN B 1 291 ? 49.12103  -35.71758 16.28416  1.000 54.36740  ? 251 GLN B NE2 1 
ATOM   4258 N N   . LEU B 1 292 ? 48.66237  -41.38383 17.77766  1.000 48.22257  ? 252 LEU B N   1 
ATOM   4259 C CA  . LEU B 1 292 ? 48.39478  -42.61774 18.50505  1.000 41.13753  ? 252 LEU B CA  1 
ATOM   4260 C C   . LEU B 1 292 ? 47.78760  -42.30469 19.86502  1.000 43.22404  ? 252 LEU B C   1 
ATOM   4261 O O   . LEU B 1 292 ? 48.33644  -41.50136 20.62653  1.000 48.46172  ? 252 LEU B O   1 
ATOM   4262 C CB  . LEU B 1 292 ? 49.67703  -43.44069 18.66928  1.000 42.55995  ? 252 LEU B CB  1 
ATOM   4263 C CG  . LEU B 1 292 ? 50.44172  -43.74104 17.37501  1.000 42.42489  ? 252 LEU B CG  1 
ATOM   4264 C CD1 . LEU B 1 292 ? 51.71204  -44.53897 17.65182  1.000 44.63090  ? 252 LEU B CD1 1 
ATOM   4265 C CD2 . LEU B 1 292 ? 49.55097  -44.46597 16.37622  1.000 40.72313  ? 252 LEU B CD2 1 
ATOM   4266 N N   . PHE B 1 293 ? 46.66296  -42.95374 20.16639  1.000 45.86735  ? 253 PHE B N   1 
ATOM   4267 C CA  . PHE B 1 293 ? 45.91883  -42.74586 21.40080  1.000 51.30571  ? 253 PHE B CA  1 
ATOM   4268 C C   . PHE B 1 293 ? 45.51281  -44.09415 21.97700  1.000 54.49930  ? 253 PHE B C   1 
ATOM   4269 O O   . PHE B 1 293 ? 45.06596  -44.97958 21.24204  1.000 45.47144  ? 253 PHE B O   1 
ATOM   4270 C CB  . PHE B 1 293 ? 44.66386  -41.88845 21.16945  1.000 43.34646  ? 253 PHE B CB  1 
ATOM   4271 C CG  . PHE B 1 293 ? 44.91603  -40.64172 20.37298  1.000 52.48710  ? 253 PHE B CG  1 
ATOM   4272 C CD1 . PHE B 1 293 ? 44.96289  -40.68056 18.98880  1.000 41.02997  ? 253 PHE B CD1 1 
ATOM   4273 C CD2 . PHE B 1 293 ? 45.09300  -39.42433 21.01011  1.000 49.86567  ? 253 PHE B CD2 1 
ATOM   4274 C CE1 . PHE B 1 293 ? 45.19541  -39.53174 18.25527  1.000 51.98033  ? 253 PHE B CE1 1 
ATOM   4275 C CE2 . PHE B 1 293 ? 45.32158  -38.27143 20.28118  1.000 41.46007  ? 253 PHE B CE2 1 
ATOM   4276 C CZ  . PHE B 1 293 ? 45.37386  -38.32650 18.90420  1.000 45.04913  ? 253 PHE B CZ  1 
ATOM   4277 N N   . THR B 1 294 ? 45.67661  -44.24728 23.29120  1.000 50.15793  ? 254 THR B N   1 
ATOM   4278 C CA  . THR B 1 294 ? 45.28550  -45.46444 23.99138  1.000 48.38555  ? 254 THR B CA  1 
ATOM   4279 C C   . THR B 1 294 ? 44.61402  -45.11262 25.30955  1.000 50.45583  ? 254 THR B C   1 
ATOM   4280 O O   . THR B 1 294 ? 45.12723  -44.28743 26.07137  1.000 53.65780  ? 254 THR B O   1 
ATOM   4281 C CB  . THR B 1 294 ? 46.49022  -46.37229 24.25324  1.000 44.76482  ? 254 THR B CB  1 
ATOM   4282 O OG1 . THR B 1 294 ? 47.20058  -46.58007 23.02827  1.000 56.16322  ? 254 THR B OG1 1 
ATOM   4283 C CG2 . THR B 1 294 ? 46.02446  -47.71308 24.79402  1.000 56.12556  ? 254 THR B CG2 1 
ATOM   4284 N N   . TYR B 1 295 ? 43.47104  -45.74002 25.57623  1.000 47.22844  ? 255 TYR B N   1 
ATOM   4285 C CA  . TYR B 1 295 ? 42.78191  -45.59206 26.84996  1.000 43.96001  ? 255 TYR B CA  1 
ATOM   4286 C C   . TYR B 1 295 ? 42.45959  -46.97700 27.38192  1.000 46.61090  ? 255 TYR B C   1 
ATOM   4287 O O   . TYR B 1 295 ? 41.96527  -47.83256 26.64041  1.000 52.86004  ? 255 TYR B O   1 
ATOM   4288 C CB  . TYR B 1 295 ? 41.49565  -44.76234 26.72781  1.000 50.99997  ? 255 TYR B CB  1 
ATOM   4289 C CG  . TYR B 1 295 ? 40.71554  -44.68751 28.02688  1.000 50.71335  ? 255 TYR B CG  1 
ATOM   4290 C CD1 . TYR B 1 295 ? 41.08989  -43.80918 29.03680  1.000 48.64393  ? 255 TYR B CD1 1 
ATOM   4291 C CD2 . TYR B 1 295 ? 39.62166  -45.51265 28.25317  1.000 52.70033  ? 255 TYR B CD2 1 
ATOM   4292 C CE1 . TYR B 1 295 ? 40.38837  -43.74507 30.22734  1.000 45.11682  ? 255 TYR B CE1 1 
ATOM   4293 C CE2 . TYR B 1 295 ? 38.91598  -45.45621 29.44086  1.000 48.61567  ? 255 TYR B CE2 1 
ATOM   4294 C CZ  . TYR B 1 295 ? 39.30348  -44.57140 30.42334  1.000 45.08951  ? 255 TYR B CZ  1 
ATOM   4295 O OH  . TYR B 1 295 ? 38.60290  -44.51205 31.60521  1.000 46.95729  ? 255 TYR B OH  1 
ATOM   4296 N N   . GLU B 1 296 ? 42.73999  -47.19149 28.66251  1.000 47.37949  ? 256 GLU B N   1 
ATOM   4297 C CA  . GLU B 1 296 ? 42.57332  -48.49331 29.28562  1.000 56.97217  ? 256 GLU B CA  1 
ATOM   4298 C C   . GLU B 1 296 ? 42.06127  -48.30855 30.70307  1.000 51.84192  ? 256 GLU B C   1 
ATOM   4299 O O   . GLU B 1 296 ? 42.50359  -47.40484 31.41751  1.000 50.23577  ? 256 GLU B O   1 
ATOM   4300 C CB  . GLU B 1 296 ? 43.88656  -49.27584 29.30728  1.000 45.18752  ? 256 GLU B CB  1 
ATOM   4301 C CG  . GLU B 1 296 ? 43.71611  -50.73713 29.66711  1.000 70.99194  ? 256 GLU B CG  1 
ATOM   4302 C CD  . GLU B 1 296 ? 44.94812  -51.54961 29.35101  1.000 81.14809  ? 256 GLU B CD  1 
ATOM   4303 O OE1 . GLU B 1 296 ? 45.83684  -51.02438 28.64871  1.000 76.45191  ? 256 GLU B OE1 1 
ATOM   4304 O OE2 . GLU B 1 296 ? 45.03289  -52.70941 29.80563  1.000 86.10432  ? 256 GLU B OE2 1 
ATOM   4305 N N   . MET B 1 297 ? 41.12811  -49.16777 31.10467  1.000 47.11447  ? 257 MET B N   1 
ATOM   4306 C CA  . MET B 1 297 ? 40.61231  -49.13935 32.46360  1.000 44.71543  ? 257 MET B CA  1 
ATOM   4307 C C   . MET B 1 297 ? 40.29152  -50.55150 32.93119  1.000 50.01543  ? 257 MET B C   1 
ATOM   4308 O O   . MET B 1 297 ? 39.73024  -51.35131 32.17918  1.000 48.80774  ? 257 MET B O   1 
ATOM   4309 C CB  . MET B 1 297 ? 39.37778  -48.23457 32.53500  1.000 45.04256  ? 257 MET B CB  1 
ATOM   4310 C CG  . MET B 1 297 ? 38.36268  -48.49959 31.43313  1.000 52.55690  ? 257 MET B CG  1 
ATOM   4311 S SD  . MET B 1 297 ? 36.87978  -47.49013 31.60723  1.000 62.50272  ? 257 MET B SD  1 
ATOM   4312 C CE  . MET B 1 297 ? 36.87775  -47.22552 33.37167  1.000 47.51235  ? 257 MET B CE  1 
ATOM   4313 N N   . ARG B 1 298 ? 40.65075  -50.84287 34.17992  1.000 43.99403  ? 258 ARG B N   1 
ATOM   4314 C CA  . ARG B 1 298 ? 40.36155  -52.11985 34.82889  1.000 43.83388  ? 258 ARG B CA  1 
ATOM   4315 C C   . ARG B 1 298 ? 39.66155  -51.82951 36.14890  1.000 48.52343  ? 258 ARG B C   1 
ATOM   4316 O O   . ARG B 1 298 ? 40.29811  -51.36842 37.10225  1.000 57.00460  ? 258 ARG B O   1 
ATOM   4317 C CB  . ARG B 1 298 ? 41.63615  -52.94050 35.04353  1.000 46.57829  ? 258 ARG B CB  1 
ATOM   4318 C CG  . ARG B 1 298 ? 42.36189  -53.27735 33.75571  1.000 56.13264  ? 258 ARG B CG  1 
ATOM   4319 C CD  . ARG B 1 298 ? 43.47397  -54.28298 33.98670  1.000 69.68272  ? 258 ARG B CD  1 
ATOM   4320 N NE  . ARG B 1 298 ? 44.20254  -54.54630 32.75272  1.000 84.15815  ? 258 ARG B NE  1 
ATOM   4321 C CZ  . ARG B 1 298 ? 43.86454  -55.48694 31.88047  1.000 83.60000  ? 258 ARG B CZ  1 
ATOM   4322 N NH1 . ARG B 1 298 ? 42.83546  -56.29063 32.09529  1.000 66.61532  ? 258 ARG B NH1 1 
ATOM   4323 N NH2 . ARG B 1 298 ? 44.57161  -55.62065 30.76212  1.000 89.23527  ? 258 ARG B NH2 1 
ATOM   4324 N N   . ILE B 1 299 ? 38.35368  -52.09802 36.20589  1.000 44.26327  ? 259 ILE B N   1 
ATOM   4325 C CA  . ILE B 1 299 ? 37.49716  -51.57239 37.26091  1.000 49.90296  ? 259 ILE B CA  1 
ATOM   4326 C C   . ILE B 1 299 ? 36.43252  -52.58437 37.66605  1.000 48.25455  ? 259 ILE B C   1 
ATOM   4327 O O   . ILE B 1 299 ? 36.11432  -53.52636 36.93644  1.000 50.31269  ? 259 ILE B O   1 
ATOM   4328 C CB  . ILE B 1 299 ? 36.82266  -50.24878 36.83066  1.000 57.26151  ? 259 ILE B CB  1 
ATOM   4329 C CG1 . ILE B 1 299 ? 36.31703  -50.34815 35.38747  1.000 45.74200  ? 259 ILE B CG1 1 
ATOM   4330 C CG2 . ILE B 1 299 ? 37.78164  -49.07264 36.99657  1.000 50.85890  ? 259 ILE B CG2 1 
ATOM   4331 C CD1 . ILE B 1 299 ? 34.93125  -50.94346 35.24507  1.000 56.57689  ? 259 ILE B CD1 1 
ATOM   4332 N N   . ASN B 1 300 ? 35.88473  -52.36841 38.85834  1.000 48.63410  ? 260 ASN B N   1 
ATOM   4333 C CA  . ASN B 1 300 ? 34.65555  -53.03113 39.27265  1.000 44.04018  ? 260 ASN B CA  1 
ATOM   4334 C C   . ASN B 1 300 ? 33.49018  -52.41396 38.50148  1.000 47.31891  ? 260 ASN B C   1 
ATOM   4335 O O   . ASN B 1 300 ? 33.18906  -51.22647 38.66989  1.000 43.72468  ? 260 ASN B O   1 
ATOM   4336 C CB  . ASN B 1 300 ? 34.48114  -52.87028 40.78265  1.000 39.61518  ? 260 ASN B CB  1 
ATOM   4337 C CG  . ASN B 1 300 ? 33.24351  -53.56452 41.32529  1.000 45.36600  ? 260 ASN B CG  1 
ATOM   4338 O OD1 . ASN B 1 300 ? 32.16357  -53.50788 40.74416  1.000 42.04820  ? 260 ASN B OD1 1 
ATOM   4339 N ND2 . ASN B 1 300 ? 33.40575  -54.22881 42.46234  1.000 48.84827  ? 260 ASN B ND2 1 
ATOM   4340 N N   . ASN B 1 301 ? 32.83618  -53.21704 37.65220  1.000 44.76272  ? 261 ASN B N   1 
ATOM   4341 C CA  . ASN B 1 301 ? 31.84644  -52.67062 36.72432  1.000 47.29007  ? 261 ASN B CA  1 
ATOM   4342 C C   . ASN B 1 301 ? 30.69526  -51.96868 37.43898  1.000 51.18328  ? 261 ASN B C   1 
ATOM   4343 O O   . ASN B 1 301 ? 30.47830  -50.77067 37.18453  1.000 44.64720  ? 261 ASN B O   1 
ATOM   4344 C CB  . ASN B 1 301 ? 31.37413  -53.77481 35.76976  1.000 50.62735  ? 261 ASN B CB  1 
ATOM   4345 C CG  . ASN B 1 301 ? 30.51876  -53.24343 34.62876  1.000 60.50020  ? 261 ASN B CG  1 
ATOM   4346 O OD1 . ASN B 1 301 ? 30.02036  -52.11892 34.67237  1.000 68.47332  ? 261 ASN B OD1 1 
ATOM   4347 N ND2 . ASN B 1 301 ? 30.35802  -54.05401 33.59028  1.000 63.63210  ? 261 ASN B ND2 1 
ATOM   4348 N N   . PRO B 1 302 ? 29.92185  -52.62020 38.32131  1.000 55.27993  ? 262 PRO B N   1 
ATOM   4349 C CA  . PRO B 1 302 ? 28.83082  -51.87735 38.98134  1.000 48.90333  ? 262 PRO B CA  1 
ATOM   4350 C C   . PRO B 1 302 ? 29.31788  -50.73492 39.85548  1.000 52.12638  ? 262 PRO B C   1 
ATOM   4351 O O   . PRO B 1 302 ? 28.64767  -49.69767 39.94028  1.000 50.08272  ? 262 PRO B O   1 
ATOM   4352 C CB  . PRO B 1 302 ? 28.11158  -52.95593 39.80351  1.000 44.14084  ? 262 PRO B CB  1 
ATOM   4353 C CG  . PRO B 1 302 ? 29.10803  -54.05001 39.96774  1.000 44.72926  ? 262 PRO B CG  1 
ATOM   4354 C CD  . PRO B 1 302 ? 29.91875  -54.04288 38.71477  1.000 43.39849  ? 262 PRO B CD  1 
ATOM   4355 N N   . ALA B 1 303 ? 30.45320  -50.90913 40.53547  1.000 47.93860  ? 263 ALA B N   1 
ATOM   4356 C CA  . ALA B 1 303 ? 31.00680  -49.82996 41.34830  1.000 49.40077  ? 263 ALA B CA  1 
ATOM   4357 C C   . ALA B 1 303 ? 31.25260  -48.58444 40.50810  1.000 46.46653  ? 263 ALA B C   1 
ATOM   4358 O O   . ALA B 1 303 ? 30.91309  -47.46691 40.91464  1.000 47.91746  ? 263 ALA B O   1 
ATOM   4359 C CB  . ALA B 1 303 ? 32.29966  -50.28803 42.02105  1.000 46.84856  ? 263 ALA B CB  1 
ATOM   4360 N N   . LEU B 1 304 ? 31.85952  -48.75939 39.33378  1.000 45.73653  ? 264 LEU B N   1 
ATOM   4361 C CA  . LEU B 1 304 ? 32.12995  -47.62184 38.46367  1.000 48.76309  ? 264 LEU B CA  1 
ATOM   4362 C C   . LEU B 1 304 ? 30.83943  -47.03729 37.90698  1.000 53.99610  ? 264 LEU B C   1 
ATOM   4363 O O   . LEU B 1 304 ? 30.65158  -45.81504 37.90476  1.000 54.01071  ? 264 LEU B O   1 
ATOM   4364 C CB  . LEU B 1 304 ? 33.04999  -48.03788 37.31983  1.000 47.25682  ? 264 LEU B CB  1 
ATOM   4365 C CG  . LEU B 1 304 ? 33.37731  -46.88296 36.37341  1.000 49.76181  ? 264 LEU B CG  1 
ATOM   4366 C CD1 . LEU B 1 304 ? 34.41117  -45.94542 36.98216  1.000 52.81178  ? 264 LEU B CD1 1 
ATOM   4367 C CD2 . LEU B 1 304 ? 33.81274  -47.38893 35.01578  1.000 60.43746  ? 264 LEU B CD2 1 
ATOM   4368 N N   . THR B 1 305 ? 29.95069  -47.89978 37.40305  1.000 49.40988  ? 265 THR B N   1 
ATOM   4369 C CA  . THR B 1 305 ? 28.70113  -47.43156 36.80957  1.000 49.83820  ? 265 THR B CA  1 
ATOM   4370 C C   . THR B 1 305 ? 27.87394  -46.63129 37.80748  1.000 53.80889  ? 265 THR B C   1 
ATOM   4371 O O   . THR B 1 305 ? 27.33292  -45.57264 37.46805  1.000 52.73294  ? 265 THR B O   1 
ATOM   4372 C CB  . THR B 1 305 ? 27.89410  -48.61751 36.27413  1.000 47.95504  ? 265 THR B CB  1 
ATOM   4373 O OG1 . THR B 1 305 ? 28.64907  -49.30082 35.26567  1.000 53.30794  ? 265 THR B OG1 1 
ATOM   4374 C CG2 . THR B 1 305 ? 26.58447  -48.14693 35.67294  1.000 45.46792  ? 265 THR B CG2 1 
ATOM   4375 N N   . SER B 1 306 ? 27.76912  -47.11596 39.04523  1.000 47.98403  ? 266 SER B N   1 
ATOM   4376 C CA  . SER B 1 306 ? 27.00701  -46.38938 40.05484  1.000 52.12601  ? 266 SER B CA  1 
ATOM   4377 C C   . SER B 1 306 ? 27.66517  -45.05803 40.39762  1.000 57.00730  ? 266 SER B C   1 
ATOM   4378 O O   . SER B 1 306 ? 26.97304  -44.06500 40.64824  1.000 51.66282  ? 266 SER B O   1 
ATOM   4379 C CB  . SER B 1 306 ? 26.85081  -47.24867 41.30617  1.000 48.02352  ? 266 SER B CB  1 
ATOM   4380 O OG  . SER B 1 306 ? 28.11732  -47.56278 41.85093  1.000 51.06284  ? 266 SER B OG  1 
ATOM   4381 N N   . GLN B 1 307 ? 28.99940  -45.01552 40.41781  1.000 48.47161  ? 267 GLN B N   1 
ATOM   4382 C CA  . GLN B 1 307 ? 29.68753  -43.76018 40.70184  1.000 46.85674  ? 267 GLN B CA  1 
ATOM   4383 C C   . GLN B 1 307 ? 29.44199  -42.73585 39.60102  1.000 54.56311  ? 267 GLN B C   1 
ATOM   4384 O O   . GLN B 1 307 ? 29.22352  -41.55186 39.88478  1.000 40.51510  ? 267 GLN B O   1 
ATOM   4385 C CB  . GLN B 1 307 ? 31.18570  -44.00243 40.88253  1.000 46.99143  ? 267 GLN B CB  1 
ATOM   4386 C CG  . GLN B 1 307 ? 32.00011  -42.72444 41.04135  1.000 36.62113  ? 267 GLN B CG  1 
ATOM   4387 C CD  . GLN B 1 307 ? 31.67180  -41.98346 42.32373  1.000 44.18714  ? 267 GLN B CD  1 
ATOM   4388 O OE1 . GLN B 1 307 ? 32.28847  -42.21417 43.36358  1.000 53.13611  ? 267 GLN B OE1 1 
ATOM   4389 N NE2 . GLN B 1 307 ? 30.69964  -41.08065 42.25358  1.000 48.93413  ? 267 GLN B NE2 1 
ATOM   4390 N N   . VAL B 1 308 ? 29.48006  -43.17342 38.33952  1.000 45.07094  ? 268 VAL B N   1 
ATOM   4391 C CA  . VAL B 1 308 ? 29.21416  -42.27019 37.22308  1.000 44.26892  ? 268 VAL B CA  1 
ATOM   4392 C C   . VAL B 1 308 ? 27.79529  -41.72418 37.30432  1.000 50.67146  ? 268 VAL B C   1 
ATOM   4393 O O   . VAL B 1 308 ? 27.55461  -40.53636 37.05287  1.000 53.06334  ? 268 VAL B O   1 
ATOM   4394 C CB  . VAL B 1 308 ? 29.46816  -42.99020 35.88566  1.000 47.33519  ? 268 VAL B CB  1 
ATOM   4395 C CG1 . VAL B 1 308 ? 28.94063  -42.16324 34.71984  1.000 44.09908  ? 268 VAL B CG1 1 
ATOM   4396 C CG2 . VAL B 1 308 ? 30.95337  -43.27992 35.71123  1.000 45.48009  ? 268 VAL B CG2 1 
ATOM   4397 N N   . MET B 1 309 ? 26.83569  -42.57917 37.66520  1.000 42.06628  ? 269 MET B N   1 
ATOM   4398 C CA  . MET B 1 309 ? 25.45217  -42.13237 37.79142  1.000 51.94485  ? 269 MET B CA  1 
ATOM   4399 C C   . MET B 1 309 ? 25.29764  -41.10450 38.90631  1.000 49.31521  ? 269 MET B C   1 
ATOM   4400 O O   . MET B 1 309 ? 24.49932  -40.16760 38.78868  1.000 43.85652  ? 269 MET B O   1 
ATOM   4401 C CB  . MET B 1 309 ? 24.53557  -43.33155 38.02884  1.000 45.41458  ? 269 MET B CB  1 
ATOM   4402 C CG  . MET B 1 309 ? 24.48019  -44.29297 36.85604  1.000 51.64399  ? 269 MET B CG  1 
ATOM   4403 S SD  . MET B 1 309 ? 23.53802  -45.78260 37.21340  1.000 56.84035  ? 269 MET B SD  1 
ATOM   4404 C CE  . MET B 1 309 ? 21.86901  -45.16584 37.04061  1.000 58.80163  ? 269 MET B CE  1 
ATOM   4405 N N   . ILE B 1 310 ? 26.04738  -41.26368 39.99926  1.000 49.40281  ? 270 ILE B N   1 
ATOM   4406 C CA  . ILE B 1 310 ? 25.99294  -40.27794 41.07526  1.000 42.84814  ? 270 ILE B CA  1 
ATOM   4407 C C   . ILE B 1 310 ? 26.62159  -38.96765 40.62037  1.000 47.55604  ? 270 ILE B C   1 
ATOM   4408 O O   . ILE B 1 310 ? 26.09679  -37.88146 40.89506  1.000 48.05726  ? 270 ILE B O   1 
ATOM   4409 C CB  . ILE B 1 310 ? 26.66471  -40.82784 42.34873  1.000 53.22389  ? 270 ILE B CB  1 
ATOM   4410 C CG1 . ILE B 1 310 ? 25.62377  -41.46974 43.26806  1.000 53.18365  ? 270 ILE B CG1 1 
ATOM   4411 C CG2 . ILE B 1 310 ? 27.41639  -39.72848 43.09444  1.000 41.94687  ? 270 ILE B CG2 1 
ATOM   4412 C CD1 . ILE B 1 310 ? 24.84664  -42.60430 42.64025  1.000 43.20322  ? 270 ILE B CD1 1 
ATOM   4413 N N   . ALA B 1 311 ? 27.74607  -39.04643 39.90624  1.000 47.00095  ? 271 ALA B N   1 
ATOM   4414 C CA  . ALA B 1 311 ? 28.33972  -37.84078 39.34284  1.000 45.63771  ? 271 ALA B CA  1 
ATOM   4415 C C   . ALA B 1 311 ? 27.38951  -37.18333 38.35176  1.000 50.30985  ? 271 ALA B C   1 
ATOM   4416 O O   . ALA B 1 311 ? 27.33767  -35.95185 38.25089  1.000 41.46702  ? 271 ALA B O   1 
ATOM   4417 C CB  . ALA B 1 311 ? 29.67351  -38.17180 38.67562  1.000 40.23676  ? 271 ALA B CB  1 
ATOM   4418 N N   . SER B 1 312 ? 26.63293  -37.99168 37.60519  1.000 38.29254  ? 272 SER B N   1 
ATOM   4419 C CA  . SER B 1 312 ? 25.64326  -37.43601 36.68875  1.000 47.93263  ? 272 SER B CA  1 
ATOM   4420 C C   . SER B 1 312 ? 24.49729  -36.77803 37.44764  1.000 49.01788  ? 272 SER B C   1 
ATOM   4421 O O   . SER B 1 312 ? 23.94565  -35.76890 36.99408  1.000 41.17027  ? 272 SER B O   1 
ATOM   4422 C CB  . SER B 1 312 ? 25.11519  -38.52631 35.75624  1.000 49.18196  ? 272 SER B CB  1 
ATOM   4423 O OG  . SER B 1 312 ? 26.14524  -39.01595 34.91504  1.000 46.86505  ? 272 SER B OG  1 
ATOM   4424 N N   . ALA B 1 313 ? 24.11652  -37.34099 38.59803  1.000 44.68875  ? 273 ALA B N   1 
ATOM   4425 C CA  . ALA B 1 313 ? 23.11162  -36.69663 39.43804  1.000 51.80376  ? 273 ALA B CA  1 
ATOM   4426 C C   . ALA B 1 313 ? 23.55835  -35.29939 39.84312  1.000 46.86115  ? 273 ALA B C   1 
ATOM   4427 O O   . ALA B 1 313 ? 22.75134  -34.36275 39.87775  1.000 48.93273  ? 273 ALA B O   1 
ATOM   4428 C CB  . ALA B 1 313 ? 22.82933  -37.55308 40.67164  1.000 36.92517  ? 273 ALA B CB  1 
ATOM   4429 N N   . ARG B 1 314 ? 24.84254  -35.14817 40.16827  1.000 47.78828  ? 274 ARG B N   1 
ATOM   4430 C CA  . ARG B 1 314 ? 25.39711  -33.82701 40.43496  1.000 46.05821  ? 274 ARG B CA  1 
ATOM   4431 C C   . ARG B 1 314 ? 25.26384  -32.91643 39.21848  1.000 45.52188  ? 274 ARG B C   1 
ATOM   4432 O O   . ARG B 1 314 ? 24.87391  -31.74982 39.34486  1.000 49.63667  ? 274 ARG B O   1 
ATOM   4433 C CB  . ARG B 1 314 ? 26.85953  -33.96800 40.85716  1.000 43.81022  ? 274 ARG B CB  1 
ATOM   4434 C CG  . ARG B 1 314 ? 27.55676  -32.66603 41.17451  1.000 46.32230  ? 274 ARG B CG  1 
ATOM   4435 C CD  . ARG B 1 314 ? 29.01236  -32.90823 41.54757  1.000 51.55626  ? 274 ARG B CD  1 
ATOM   4436 N NE  . ARG B 1 314 ? 29.15620  -33.75348 42.72769  1.000 50.76475  ? 274 ARG B NE  1 
ATOM   4437 C CZ  . ARG B 1 314 ? 29.67391  -34.97478 42.71810  1.000 53.97741  ? 274 ARG B CZ  1 
ATOM   4438 N NH1 . ARG B 1 314 ? 30.14256  -35.51836 41.60680  1.000 43.49042  ? 274 ARG B NH1 1 
ATOM   4439 N NH2 . ARG B 1 314 ? 29.73469  -35.66335 43.85482  1.000 49.63046  ? 274 ARG B NH2 1 
ATOM   4440 N N   . ALA B 1 315 ? 25.57925  -33.43571 38.02923  1.000 35.49770  ? 275 ALA B N   1 
ATOM   4441 C CA  . ALA B 1 315 ? 25.50585  -32.63220 36.81199  1.000 47.90779  ? 275 ALA B CA  1 
ATOM   4442 C C   . ALA B 1 315 ? 24.07188  -32.26014 36.45029  1.000 48.56292  ? 275 ALA B C   1 
ATOM   4443 O O   . ALA B 1 315 ? 23.83764  -31.18044 35.89400  1.000 43.30645  ? 275 ALA B O   1 
ATOM   4444 C CB  . ALA B 1 315 ? 26.16762  -33.37734 35.65134  1.000 39.04013  ? 275 ALA B CB  1 
ATOM   4445 N N   . ALA B 1 316 ? 23.10898  -33.13949 36.74280  1.000 48.42808  ? 276 ALA B N   1 
ATOM   4446 C CA  . ALA B 1 316 ? 21.71458  -32.87180 36.39715  1.000 49.18661  ? 276 ALA B CA  1 
ATOM   4447 C C   . ALA B 1 316 ? 21.20808  -31.59390 37.05716  1.000 46.37182  ? 276 ALA B C   1 
ATOM   4448 O O   . ALA B 1 316 ? 20.42082  -30.84806 36.46105  1.000 45.07859  ? 276 ALA B O   1 
ATOM   4449 C CB  . ALA B 1 316 ? 20.84195  -34.06443 36.79029  1.000 49.58737  ? 276 ALA B CB  1 
ATOM   4450 N N   . MET B 1 317 ? 21.65848  -31.31874 38.28431  1.000 43.69542  ? 277 MET B N   1 
ATOM   4451 C CA  . MET B 1 317 ? 21.25599  -30.11403 38.99999  1.000 50.32515  ? 277 MET B CA  1 
ATOM   4452 C C   . MET B 1 317 ? 21.76825  -28.83645 38.34335  1.000 46.67777  ? 277 MET B C   1 
ATOM   4453 O O   . MET B 1 317 ? 21.34627  -27.74508 38.74199  1.000 55.49551  ? 277 MET B O   1 
ATOM   4454 C CB  . MET B 1 317 ? 21.74855  -30.18391 40.45009  1.000 44.52936  ? 277 MET B CB  1 
ATOM   4455 C CG  . MET B 1 317 ? 21.20815  -31.37172 41.22467  1.000 48.09635  ? 277 MET B CG  1 
ATOM   4456 S SD  . MET B 1 317 ? 19.41529  -31.35141 41.39867  1.000 53.13655  ? 277 MET B SD  1 
ATOM   4457 C CE  . MET B 1 317 ? 19.20118  -29.96520 42.51342  1.000 32.81698  ? 277 MET B CE  1 
ATOM   4458 N N   . ARG B 1 318 ? 22.65052  -28.94069 37.34986  1.000 45.28993  ? 278 ARG B N   1 
ATOM   4459 C CA  . ARG B 1 318 ? 23.24930  -27.77735 36.71080  1.000 46.27629  ? 278 ARG B CA  1 
ATOM   4460 C C   . ARG B 1 318 ? 22.80489  -27.61553 35.26595  1.000 47.02581  ? 278 ARG B C   1 
ATOM   4461 O O   . ARG B 1 318 ? 23.33869  -26.75244 34.55408  1.000 50.88336  ? 278 ARG B O   1 
ATOM   4462 C CB  . ARG B 1 318 ? 24.77286  -27.86674 36.77196  1.000 39.45601  ? 278 ARG B CB  1 
ATOM   4463 C CG  . ARG B 1 318 ? 25.32147  -27.98148 38.17495  1.000 44.87135  ? 278 ARG B CG  1 
ATOM   4464 C CD  . ARG B 1 318 ? 26.77729  -28.40410 38.16607  1.000 45.95245  ? 278 ARG B CD  1 
ATOM   4465 N NE  . ARG B 1 318 ? 27.40128  -28.15633 39.45823  1.000 42.88380  ? 278 ARG B NE  1 
ATOM   4466 C CZ  . ARG B 1 318 ? 28.46899  -28.79921 39.90732  1.000 49.02390  ? 278 ARG B CZ  1 
ATOM   4467 N NH1 . ARG B 1 318 ? 29.04436  -29.75848 39.20174  1.000 49.42602  ? 278 ARG B NH1 1 
ATOM   4468 N NH2 . ARG B 1 318 ? 28.96477  -28.47962 41.09915  1.000 47.56071  ? 278 ARG B NH2 1 
ATOM   4469 N N   . GLN B 1 319 ? 21.83992  -28.41205 34.81716  1.000 48.41240  ? 279 GLN B N   1 
ATOM   4470 C CA  . GLN B 1 319 ? 21.40277  -28.39010 33.43230  1.000 54.69968  ? 279 GLN B CA  1 
ATOM   4471 C C   . GLN B 1 319 ? 20.04678  -27.70767 33.30157  1.000 55.57061  ? 279 GLN B C   1 
ATOM   4472 O O   . GLN B 1 319 ? 19.30504  -27.54370 34.28321  1.000 47.64231  ? 279 GLN B O   1 
ATOM   4473 C CB  . GLN B 1 319 ? 21.31313  -29.80537 32.86148  1.000 47.48037  ? 279 GLN B CB  1 
ATOM   4474 C CG  . GLN B 1 319 ? 22.59419  -30.60232 32.99423  1.000 53.05180  ? 279 GLN B CG  1 
ATOM   4475 C CD  . GLN B 1 319 ? 23.81310  -29.80281 32.58145  1.000 48.83984  ? 279 GLN B CD  1 
ATOM   4476 O OE1 . GLN B 1 319 ? 23.87120  -29.27041 31.47578  1.000 41.57117  ? 279 GLN B OE1 1 
ATOM   4477 N NE2 . GLN B 1 319 ? 24.79825  -29.72025 33.46932  1.000 43.02643  ? 279 GLN B NE2 1 
ATOM   4478 N N   . LYS B 1 320 ? 19.74656  -27.28201 32.06723  1.000 55.41723  ? 280 LYS B N   1 
ATOM   4479 C CA  . LYS B 1 320 ? 18.40006  -26.85603 31.71420  1.000 47.43240  ? 280 LYS B CA  1 
ATOM   4480 C C   . LYS B 1 320 ? 17.48981  -28.08059 31.58003  1.000 54.74637  ? 280 LYS B C   1 
ATOM   4481 O O   . LYS B 1 320 ? 17.97453  -29.21401 31.46004  1.000 64.02453  ? 280 LYS B O   1 
ATOM   4482 C CB  . LYS B 1 320 ? 18.39219  -26.10866 30.39053  1.000 45.92207  ? 280 LYS B CB  1 
ATOM   4483 C CG  . LYS B 1 320 ? 19.13494  -24.79168 30.26505  1.000 61.08113  ? 280 LYS B CG  1 
ATOM   4484 C CD  . LYS B 1 320 ? 18.97326  -24.32275 28.80541  1.000 84.36921  ? 280 LYS B CD  1 
ATOM   4485 C CE  . LYS B 1 320 ? 19.75906  -23.07046 28.43781  1.000 106.31924 ? 280 LYS B CE  1 
ATOM   4486 N NZ  . LYS B 1 320 ? 19.40422  -22.61827 27.03876  1.000 107.53132 ? 280 LYS B NZ  1 
ATOM   4487 N N   . PRO B 1 321 ? 16.17231  -27.88907 31.65344  1.000 56.89030  ? 281 PRO B N   1 
ATOM   4488 C CA  . PRO B 1 321 ? 15.26770  -29.02076 31.44602  1.000 54.95082  ? 281 PRO B CA  1 
ATOM   4489 C C   . PRO B 1 321 ? 15.55109  -29.69758 30.12068  1.000 57.54614  ? 281 PRO B C   1 
ATOM   4490 O O   . PRO B 1 321 ? 15.84293  -29.03932 29.12804  1.000 51.56197  ? 281 PRO B O   1 
ATOM   4491 C CB  . PRO B 1 321 ? 13.87952  -28.37215 31.47164  1.000 51.94414  ? 281 PRO B CB  1 
ATOM   4492 C CG  . PRO B 1 321 ? 14.04591  -27.17574 32.33312  1.000 49.29210  ? 281 PRO B CG  1 
ATOM   4493 C CD  . PRO B 1 321 ? 15.44490  -26.67346 32.03076  1.000 44.76673  ? 281 PRO B CD  1 
ATOM   4494 N N   . GLY B 1 322 ? 15.46357  -31.02548 30.11675  1.000 50.37920  ? 282 GLY B N   1 
ATOM   4495 C CA  . GLY B 1 322 ? 15.72784  -31.80491 28.92449  1.000 41.70994  ? 282 GLY B CA  1 
ATOM   4496 C C   . GLY B 1 322 ? 16.42410  -33.11783 29.20395  1.000 55.65402  ? 282 GLY B C   1 
ATOM   4497 O O   . GLY B 1 322 ? 16.69096  -33.45729 30.35906  1.000 47.18807  ? 282 GLY B O   1 
ATOM   4498 N N   . ALA B 1 323 ? 16.71145  -33.86955 28.14864  1.000 51.23866  ? 283 ALA B N   1 
ATOM   4499 C CA  . ALA B 1 323 ? 17.40629  -35.14215 28.24607  1.000 51.53037  ? 283 ALA B CA  1 
ATOM   4500 C C   . ALA B 1 323 ? 18.78325  -35.02289 27.60819  1.000 50.79936  ? 283 ALA B C   1 
ATOM   4501 O O   . ALA B 1 323 ? 18.92445  -34.45219 26.52149  1.000 45.17622  ? 283 ALA B O   1 
ATOM   4502 C CB  . ALA B 1 323 ? 16.60300  -36.25222 27.56728  1.000 44.08981  ? 283 ALA B CB  1 
ATOM   4503 N N   . TYR B 1 324 ? 19.79585  -35.56741 28.28247  1.000 46.57871  ? 284 TYR B N   1 
ATOM   4504 C CA  . TYR B 1 324 ? 21.17207  -35.44229 27.82781  1.000 47.88652  ? 284 TYR B CA  1 
ATOM   4505 C C   . TYR B 1 324 ? 21.88949  -36.77993 27.91607  1.000 53.61905  ? 284 TYR B C   1 
ATOM   4506 O O   . TYR B 1 324 ? 21.73450  -37.51820 28.89410  1.000 40.14197  ? 284 TYR B O   1 
ATOM   4507 C CB  . TYR B 1 324 ? 21.95670  -34.41332 28.65405  1.000 39.72895  ? 284 TYR B CB  1 
ATOM   4508 C CG  . TYR B 1 324 ? 21.30074  -33.05812 28.80091  1.000 58.14769  ? 284 TYR B CG  1 
ATOM   4509 C CD1 . TYR B 1 324 ? 20.30804  -32.84038 29.74835  1.000 49.14705  ? 284 TYR B CD1 1 
ATOM   4510 C CD2 . TYR B 1 324 ? 21.68251  -31.99257 27.99758  1.000 55.10865  ? 284 TYR B CD2 1 
ATOM   4511 C CE1 . TYR B 1 324 ? 19.71365  -31.60240 29.89107  1.000 51.55471  ? 284 TYR B CE1 1 
ATOM   4512 C CE2 . TYR B 1 324 ? 21.09255  -30.75061 28.13272  1.000 47.54539  ? 284 TYR B CE2 1 
ATOM   4513 C CZ  . TYR B 1 324 ? 20.10972  -30.56074 29.07928  1.000 48.82347  ? 284 TYR B CZ  1 
ATOM   4514 O OH  . TYR B 1 324 ? 19.52686  -29.32135 29.20729  1.000 54.82447  ? 284 TYR B OH  1 
ATOM   4515 N N   . THR B 1 325 ? 22.67732  -37.08226 26.88931  1.000 52.91267  ? 285 THR B N   1 
ATOM   4516 C CA  . THR B 1 325 ? 23.73271  -38.06713 27.03984  1.000 50.88303  ? 285 THR B CA  1 
ATOM   4517 C C   . THR B 1 325 ? 24.96692  -37.39726 27.64186  1.000 47.20247  ? 285 THR B C   1 
ATOM   4518 O O   . THR B 1 325 ? 25.02069  -36.17673 27.81433  1.000 49.24996  ? 285 THR B O   1 
ATOM   4519 C CB  . THR B 1 325 ? 24.06099  -38.72448 25.69994  1.000 50.64041  ? 285 THR B CB  1 
ATOM   4520 O OG1 . THR B 1 325 ? 24.49046  -37.72707 24.76667  1.000 49.60268  ? 285 THR B OG1 1 
ATOM   4521 C CG2 . THR B 1 325 ? 22.83571  -39.43286 25.14653  1.000 48.13650  ? 285 THR B CG2 1 
ATOM   4522 N N   . MET B 1 326 ? 25.97147  -38.21132 27.97333  1.000 53.07834  ? 286 MET B N   1 
ATOM   4523 C CA  . MET B 1 326 ? 27.12562  -37.68365 28.69464  1.000 52.70604  ? 286 MET B CA  1 
ATOM   4524 C C   . MET B 1 326 ? 28.03452  -36.81769 27.82877  1.000 47.13554  ? 286 MET B C   1 
ATOM   4525 O O   . MET B 1 326 ? 28.85065  -36.06990 28.37772  1.000 54.27258  ? 286 MET B O   1 
ATOM   4526 C CB  . MET B 1 326 ? 27.93396  -38.82331 29.31760  1.000 50.59123  ? 286 MET B CB  1 
ATOM   4527 C CG  . MET B 1 326 ? 27.21477  -39.53831 30.44970  1.000 52.63007  ? 286 MET B CG  1 
ATOM   4528 S SD  . MET B 1 326 ? 28.31772  -40.56238 31.44678  1.000 52.75317  ? 286 MET B SD  1 
ATOM   4529 C CE  . MET B 1 326 ? 29.12827  -39.31982 32.44780  1.000 51.95565  ? 286 MET B CE  1 
ATOM   4530 N N   . ILE B 1 327 ? 27.91799  -36.88534 26.50258  1.000 45.89301  ? 287 ILE B N   1 
ATOM   4531 C CA  . ILE B 1 327 ? 28.75908  -36.05707 25.64324  1.000 48.91156  ? 287 ILE B CA  1 
ATOM   4532 C C   . ILE B 1 327 ? 28.07493  -34.72068 25.38268  1.000 46.54587  ? 287 ILE B C   1 
ATOM   4533 O O   . ILE B 1 327 ? 28.55838  -33.90750 24.58711  1.000 45.00816  ? 287 ILE B O   1 
ATOM   4534 C CB  . ILE B 1 327 ? 29.09943  -36.76723 24.31970  1.000 46.37481  ? 287 ILE B CB  1 
ATOM   4535 C CG1 . ILE B 1 327 ? 27.83630  -37.01936 23.49470  1.000 48.02037  ? 287 ILE B CG1 1 
ATOM   4536 C CG2 . ILE B 1 327 ? 29.84053  -38.07150 24.58986  1.000 44.58413  ? 287 ILE B CG2 1 
ATOM   4537 C CD1 . ILE B 1 327 ? 28.12595  -37.58779 22.12224  1.000 44.68292  ? 287 ILE B CD1 1 
ATOM   4538 N N   . GLU B 1 328 ? 26.95233  -34.47960 26.05723  1.000 47.82123  ? 288 GLU B N   1 
ATOM   4539 C CA  . GLU B 1 328 ? 26.22636  -33.22185 25.94284  1.000 45.76472  ? 288 GLU B CA  1 
ATOM   4540 C C   . GLU B 1 328 ? 26.30380  -32.39344 27.21605  1.000 43.61135  ? 288 GLU B C   1 
ATOM   4541 O O   . GLU B 1 328 ? 25.54079  -31.43433 27.36825  1.000 51.57312  ? 288 GLU B O   1 
ATOM   4542 C CB  . GLU B 1 328 ? 24.76178  -33.47472 25.58228  1.000 46.36998  ? 288 GLU B CB  1 
ATOM   4543 C CG  . GLU B 1 328 ? 24.55349  -34.41088 24.41119  1.000 51.58347  ? 288 GLU B CG  1 
ATOM   4544 C CD  . GLU B 1 328 ? 23.08663  -34.63286 24.11038  1.000 56.69308  ? 288 GLU B CD  1 
ATOM   4545 O OE1 . GLU B 1 328 ? 22.34613  -33.63261 24.01230  1.000 61.09540  ? 288 GLU B OE1 1 
ATOM   4546 O OE2 . GLU B 1 328 ? 22.67280  -35.80305 23.97301  1.000 63.66243  ? 288 GLU B OE2 1 
ATOM   4547 N N   . ILE B 1 329 ? 27.21038  -32.73004 28.12576  1.000 44.08381  ? 289 ILE B N   1 
ATOM   4548 C CA  . ILE B 1 329 ? 27.29643  -32.05292 29.41430  1.000 47.74362  ? 289 ILE B CA  1 
ATOM   4549 C C   . ILE B 1 329 ? 28.73604  -31.59093 29.60039  1.000 60.73064  ? 289 ILE B C   1 
ATOM   4550 O O   . ILE B 1 329 ? 29.66839  -32.37017 29.34554  1.000 55.07016  ? 289 ILE B O   1 
ATOM   4551 C CB  . ILE B 1 329 ? 26.86055  -32.98351 30.55829  1.000 58.06854  ? 289 ILE B CB  1 
ATOM   4552 C CG1 . ILE B 1 329 ? 25.40671  -33.42267 30.37269  1.000 53.09991  ? 289 ILE B CG1 1 
ATOM   4553 C CG2 . ILE B 1 329 ? 27.04188  -32.30224 31.90884  1.000 53.55746  ? 289 ILE B CG2 1 
ATOM   4554 C CD1 . ILE B 1 329 ? 24.43875  -32.28414 30.30536  1.000 54.99096  ? 289 ILE B CD1 1 
ATOM   4555 N N   . PRO B 1 330 ? 28.96948  -30.33978 29.99935  1.000 60.37561  ? 290 PRO B N   1 
ATOM   4556 C CA  . PRO B 1 330 ? 30.34176  -29.91261 30.30417  1.000 49.89032  ? 290 PRO B CA  1 
ATOM   4557 C C   . PRO B 1 330 ? 30.94275  -30.81109 31.37468  1.000 52.23702  ? 290 PRO B C   1 
ATOM   4558 O O   . PRO B 1 330 ? 30.29566  -31.12755 32.37493  1.000 56.00563  ? 290 PRO B O   1 
ATOM   4559 C CB  . PRO B 1 330 ? 30.17320  -28.46828 30.79352  1.000 43.92465  ? 290 PRO B CB  1 
ATOM   4560 C CG  . PRO B 1 330 ? 28.84119  -28.02574 30.27699  1.000 48.04129  ? 290 PRO B CG  1 
ATOM   4561 C CD  . PRO B 1 330 ? 27.98762  -29.25189 30.15551  1.000 55.78304  ? 290 PRO B CD  1 
ATOM   4562 N N   . ILE B 1 331 ? 32.18336  -31.24534 31.13924  1.000 44.28968  ? 291 ILE B N   1 
ATOM   4563 C CA  . ILE B 1 331 ? 32.83715  -32.18575 32.04770  1.000 48.36577  ? 291 ILE B CA  1 
ATOM   4564 C C   . ILE B 1 331 ? 32.86640  -31.63722 33.47028  1.000 43.37741  ? 291 ILE B C   1 
ATOM   4565 O O   . ILE B 1 331 ? 32.72423  -32.38704 34.44503  1.000 47.04308  ? 291 ILE B O   1 
ATOM   4566 C CB  . ILE B 1 331 ? 34.24860  -32.52494 31.53275  1.000 50.02039  ? 291 ILE B CB  1 
ATOM   4567 C CG1 . ILE B 1 331 ? 34.16213  -33.24246 30.18500  1.000 44.38023  ? 291 ILE B CG1 1 
ATOM   4568 C CG2 . ILE B 1 331 ? 34.99610  -33.38623 32.53024  1.000 44.47252  ? 291 ILE B CG2 1 
ATOM   4569 C CD1 . ILE B 1 331 ? 35.50902  -33.55481 29.58044  1.000 46.29666  ? 291 ILE B CD1 1 
ATOM   4570 N N   . ILE B 1 332 ? 33.03982  -30.32147 33.61271  1.000 44.47470  ? 292 ILE B N   1 
ATOM   4571 C CA  . ILE B 1 332 ? 33.14377  -29.72142 34.93949  1.000 46.66232  ? 292 ILE B CA  1 
ATOM   4572 C C   . ILE B 1 332 ? 31.84865  -29.89339 35.72528  1.000 47.97981  ? 292 ILE B C   1 
ATOM   4573 O O   . ILE B 1 332 ? 31.86288  -29.90273 36.96237  1.000 55.04331  ? 292 ILE B O   1 
ATOM   4574 C CB  . ILE B 1 332 ? 33.54728  -28.23658 34.81911  1.000 47.61192  ? 292 ILE B CB  1 
ATOM   4575 C CG1 . ILE B 1 332 ? 34.06299  -27.70628 36.15723  1.000 49.75342  ? 292 ILE B CG1 1 
ATOM   4576 C CG2 . ILE B 1 332 ? 32.38228  -27.39636 34.32280  1.000 44.27285  ? 292 ILE B CG2 1 
ATOM   4577 C CD1 . ILE B 1 332 ? 34.62918  -26.30661 36.08252  1.000 51.45910  ? 292 ILE B CD1 1 
ATOM   4578 N N   . ASP B 1 333 ? 30.71462  -30.04164 35.03274  1.000 50.12842  ? 293 ASP B N   1 
ATOM   4579 C CA  . ASP B 1 333 ? 29.43239  -30.18092 35.71735  1.000 59.32664  ? 293 ASP B CA  1 
ATOM   4580 C C   . ASP B 1 333 ? 29.32143  -31.47649 36.51291  1.000 52.21373  ? 293 ASP B C   1 
ATOM   4581 O O   . ASP B 1 333 ? 28.50013  -31.55358 37.43296  1.000 48.76986  ? 293 ASP B O   1 
ATOM   4582 C CB  . ASP B 1 333 ? 28.28402  -30.08712 34.71321  1.000 54.89876  ? 293 ASP B CB  1 
ATOM   4583 C CG  . ASP B 1 333 ? 28.05516  -28.67132 34.22398  1.000 54.00251  ? 293 ASP B CG  1 
ATOM   4584 O OD1 . ASP B 1 333 ? 28.73602  -27.74917 34.72112  1.000 59.53332  ? 293 ASP B OD1 1 
ATOM   4585 O OD2 . ASP B 1 333 ? 27.18853  -28.47878 33.34688  1.000 48.35601  ? 293 ASP B OD2 1 
ATOM   4586 N N   . PHE B 1 334 ? 30.12219  -32.48953 36.18808  1.000 43.07790  ? 294 PHE B N   1 
ATOM   4587 C CA  . PHE B 1 334 ? 30.10789  -33.73322 36.94575  1.000 43.17171  ? 294 PHE B CA  1 
ATOM   4588 C C   . PHE B 1 334 ? 30.92770  -33.65884 38.22636  1.000 49.38188  ? 294 PHE B C   1 
ATOM   4589 O O   . PHE B 1 334 ? 30.87177  -34.59264 39.03332  1.000 45.09593  ? 294 PHE B O   1 
ATOM   4590 C CB  . PHE B 1 334 ? 30.63848  -34.88336 36.08726  1.000 50.28042  ? 294 PHE B CB  1 
ATOM   4591 C CG  . PHE B 1 334 ? 29.80233  -35.18020 34.87600  1.000 53.90167  ? 294 PHE B CG  1 
ATOM   4592 C CD1 . PHE B 1 334 ? 28.70520  -36.01793 34.96857  1.000 50.70500  ? 294 PHE B CD1 1 
ATOM   4593 C CD2 . PHE B 1 334 ? 30.12460  -34.63907 33.64132  1.000 51.64575  ? 294 PHE B CD2 1 
ATOM   4594 C CE1 . PHE B 1 334 ? 27.93623  -36.30376 33.85906  1.000 47.18792  ? 294 PHE B CE1 1 
ATOM   4595 C CE2 . PHE B 1 334 ? 29.35923  -34.92338 32.52312  1.000 57.40251  ? 294 PHE B CE2 1 
ATOM   4596 C CZ  . PHE B 1 334 ? 28.26296  -35.75640 32.63451  1.000 49.14449  ? 294 PHE B CZ  1 
ATOM   4597 N N   . LEU B 1 335 ? 31.67987  -32.58452 38.43126  1.000 46.32967  ? 295 LEU B N   1 
ATOM   4598 C CA  . LEU B 1 335 ? 32.63834  -32.49034 39.52075  1.000 49.56704  ? 295 LEU B CA  1 
ATOM   4599 C C   . LEU B 1 335 ? 32.09624  -31.64726 40.66783  1.000 54.17534  ? 295 LEU B C   1 
ATOM   4600 O O   . LEU B 1 335 ? 31.35216  -30.68513 40.46367  1.000 56.85540  ? 295 LEU B O   1 
ATOM   4601 C CB  . LEU B 1 335 ? 33.95730  -31.89660 39.02496  1.000 51.17662  ? 295 LEU B CB  1 
ATOM   4602 C CG  . LEU B 1 335 ? 34.71423  -32.74706 38.00604  1.000 46.29598  ? 295 LEU B CG  1 
ATOM   4603 C CD1 . LEU B 1 335 ? 35.72718  -31.90607 37.24395  1.000 50.03611  ? 295 LEU B CD1 1 
ATOM   4604 C CD2 . LEU B 1 335 ? 35.38865  -33.92612 38.69069  1.000 49.32330  ? 295 LEU B CD2 1 
ATOM   4605 N N   . TYR B 1 336 ? 32.47197  -32.03382 41.88343  1.000 54.38289  ? 296 TYR B N   1 
ATOM   4606 C CA  . TYR B 1 336 ? 32.16333  -31.26975 43.08311  1.000 53.75902  ? 296 TYR B CA  1 
ATOM   4607 C C   . TYR B 1 336 ? 33.24549  -30.23249 43.35196  1.000 53.05194  ? 296 TYR B C   1 
ATOM   4608 O O   . TYR B 1 336 ? 34.43931  -30.51041 43.20846  1.000 53.69385  ? 296 TYR B O   1 
ATOM   4609 C CB  . TYR B 1 336 ? 32.02863  -32.20497 44.28586  1.000 53.29348  ? 296 TYR B CB  1 
ATOM   4610 C CG  . TYR B 1 336 ? 31.92887  -31.49539 45.61653  1.000 58.42674  ? 296 TYR B CG  1 
ATOM   4611 C CD1 . TYR B 1 336 ? 30.76460  -30.84180 45.99638  1.000 59.43376  ? 296 TYR B CD1 1 
ATOM   4612 C CD2 . TYR B 1 336 ? 33.00161  -31.48957 46.49911  1.000 49.47065  ? 296 TYR B CD2 1 
ATOM   4613 C CE1 . TYR B 1 336 ? 30.67477  -30.19485 47.21531  1.000 54.60154  ? 296 TYR B CE1 1 
ATOM   4614 C CE2 . TYR B 1 336 ? 32.92164  -30.84658 47.71835  1.000 54.86854  ? 296 TYR B CE2 1 
ATOM   4615 C CZ  . TYR B 1 336 ? 31.75613  -30.20150 48.07284  1.000 54.48318  ? 296 TYR B CZ  1 
ATOM   4616 O OH  . TYR B 1 336 ? 31.67085  -29.55985 49.28744  1.000 51.64916  ? 296 TYR B OH  1 
ATOM   4617 N N   . GLY B 1 337 ? 32.82162  -29.03791 43.74438  1.000 63.89203  ? 297 GLY B N   1 
ATOM   4618 C CA  . GLY B 1 337 ? 33.73412  -27.99349 44.16293  1.000 55.09891  ? 297 GLY B CA  1 
ATOM   4619 C C   . GLY B 1 337 ? 33.44768  -26.67213 43.47575  1.000 70.38291  ? 297 GLY B C   1 
ATOM   4620 O O   . GLY B 1 337 ? 32.59802  -26.55743 42.59478  1.000 55.31885  ? 297 GLY B O   1 
ATOM   4621 N N   . ASP B 1 338 ? 34.18315  -25.65844 43.92441  1.000 69.86841  ? 298 ASP B N   1 
ATOM   4622 C CA  . ASP B 1 338 ? 34.11337  -24.33532 43.32103  1.000 63.37741  ? 298 ASP B CA  1 
ATOM   4623 C C   . ASP B 1 338 ? 34.64176  -24.38069 41.89090  1.000 65.62644  ? 298 ASP B C   1 
ATOM   4624 O O   . ASP B 1 338 ? 35.67166  -25.00597 41.62089  1.000 60.96929  ? 298 ASP B O   1 
ATOM   4625 C CB  . ASP B 1 338 ? 34.91064  -23.34385 44.16914  1.000 71.77732  ? 298 ASP B CB  1 
ATOM   4626 C CG  . ASP B 1 338 ? 35.00873  -21.97029 43.53775  1.000 79.03736  ? 298 ASP B CG  1 
ATOM   4627 O OD1 . ASP B 1 338 ? 35.77427  -21.80900 42.56541  1.000 77.58870  ? 298 ASP B OD1 1 
ATOM   4628 O OD2 . ASP B 1 338 ? 34.32581  -21.04456 44.02336  1.000 74.95984  ? 298 ASP B OD2 1 
ATOM   4629 N N   . ARG B 1 339 ? 33.92758  -23.72102 40.97329  1.000 53.95112  ? 299 ARG B N   1 
ATOM   4630 C CA  . ARG B 1 339 ? 34.30022  -23.76183 39.56091  1.000 58.72643  ? 299 ARG B CA  1 
ATOM   4631 C C   . ARG B 1 339 ? 35.72331  -23.25361 39.34472  1.000 61.72128  ? 299 ARG B C   1 
ATOM   4632 O O   . ARG B 1 339 ? 36.52010  -23.88841 38.64376  1.000 62.86252  ? 299 ARG B O   1 
ATOM   4633 C CB  . ARG B 1 339 ? 33.29923  -22.95280 38.73485  1.000 57.20514  ? 299 ARG B CB  1 
ATOM   4634 C CG  . ARG B 1 339 ? 33.66147  -22.84213 37.26511  1.000 61.70076  ? 299 ARG B CG  1 
ATOM   4635 C CD  . ARG B 1 339 ? 32.53465  -22.20592 36.46472  1.000 67.78945  ? 299 ARG B CD  1 
ATOM   4636 N NE  . ARG B 1 339 ? 31.45890  -23.15449 36.19010  1.000 74.22056  ? 299 ARG B NE  1 
ATOM   4637 C CZ  . ARG B 1 339 ? 31.22104  -23.70210 35.00489  1.000 58.61339  ? 299 ARG B CZ  1 
ATOM   4638 N NH1 . ARG B 1 339 ? 31.97175  -23.42473 33.95167  1.000 65.52824  ? 299 ARG B NH1 1 
ATOM   4639 N NH2 . ARG B 1 339 ? 30.20585  -24.55203 34.87342  1.000 61.80934  ? 299 ARG B NH2 1 
ATOM   4640 N N   . ASP B 1 340 ? 36.06009  -22.10402 39.93722  1.000 62.45633  ? 300 ASP B N   1 
ATOM   4641 C CA  . ASP B 1 340 ? 37.40303  -21.55311 39.77179  1.000 64.35057  ? 300 ASP B CA  1 
ATOM   4642 C C   . ASP B 1 340 ? 38.44760  -22.46274 40.39955  1.000 58.97421  ? 300 ASP B C   1 
ATOM   4643 O O   . ASP B 1 340 ? 39.55042  -22.62186 39.86152  1.000 56.86561  ? 300 ASP B O   1 
ATOM   4644 C CB  . ASP B 1 340 ? 37.48354  -20.15736 40.38817  1.000 65.23362  ? 300 ASP B CB  1 
ATOM   4645 C CG  . ASP B 1 340 ? 37.11241  -19.06523 39.40985  1.000 69.20558  ? 300 ASP B CG  1 
ATOM   4646 O OD1 . ASP B 1 340 ? 36.83375  -19.38158 38.23448  1.000 66.06477  ? 300 ASP B OD1 1 
ATOM   4647 O OD2 . ASP B 1 340 ? 37.09290  -17.88926 39.82345  1.000 68.55278  ? 300 ASP B OD2 1 
ATOM   4648 N N   . GLU B 1 341 ? 38.11251  -23.07103 41.53675  1.000 60.26176  ? 301 GLU B N   1 
ATOM   4649 C CA  . GLU B 1 341 ? 39.04759  -23.96605 42.20071  1.000 63.20984  ? 301 GLU B CA  1 
ATOM   4650 C C   . GLU B 1 341 ? 39.27653  -25.23025 41.38535  1.000 58.35124  ? 301 GLU B C   1 
ATOM   4651 O O   . GLU B 1 341 ? 40.38360  -25.78027 41.39246  1.000 63.51968  ? 301 GLU B O   1 
ATOM   4652 C CB  . GLU B 1 341 ? 38.52273  -24.31094 43.59381  1.000 72.71897  ? 301 GLU B CB  1 
ATOM   4653 C CG  . GLU B 1 341 ? 39.55706  -24.19065 44.69294  1.000 87.71104  ? 301 GLU B CG  1 
ATOM   4654 C CD  . GLU B 1 341 ? 40.70403  -25.16730 44.52369  1.000 104.51429 ? 301 GLU B CD  1 
ATOM   4655 O OE1 . GLU B 1 341 ? 40.48182  -26.38384 44.69244  1.000 105.42977 ? 301 GLU B OE1 1 
ATOM   4656 O OE2 . GLU B 1 341 ? 41.82825  -24.71743 44.22079  1.000 95.68572  ? 301 GLU B OE2 1 
ATOM   4657 N N   . LEU B 1 342 ? 38.24399  -25.70535 40.68635  1.000 56.28734  ? 302 LEU B N   1 
ATOM   4658 C CA  . LEU B 1 342 ? 38.40535  -26.85294 39.80084  1.000 54.64071  ? 302 LEU B CA  1 
ATOM   4659 C C   . LEU B 1 342 ? 39.29809  -26.52245 38.61008  1.000 55.88601  ? 302 LEU B C   1 
ATOM   4660 O O   . LEU B 1 342 ? 40.16241  -27.32429 38.23558  1.000 49.63290  ? 302 LEU B O   1 
ATOM   4661 C CB  . LEU B 1 342 ? 37.03587  -27.33947 39.33396  1.000 52.13817  ? 302 LEU B CB  1 
ATOM   4662 C CG  . LEU B 1 342 ? 36.20420  -28.00491 40.42912  1.000 57.48760  ? 302 LEU B CG  1 
ATOM   4663 C CD1 . LEU B 1 342 ? 34.78848  -28.22548 39.94380  1.000 47.83037  ? 302 LEU B CD1 1 
ATOM   4664 C CD2 . LEU B 1 342 ? 36.84417  -29.31595 40.87474  1.000 52.44573  ? 302 LEU B CD2 1 
ATOM   4665 N N   . ILE B 1 343 ? 39.10655  -25.34723 38.00452  1.000 56.62643  ? 303 ILE B N   1 
ATOM   4666 C CA  . ILE B 1 343 ? 39.90945  -24.96756 36.84399  1.000 62.29508  ? 303 ILE B CA  1 
ATOM   4667 C C   . ILE B 1 343 ? 41.37953  -24.84199 37.22587  1.000 59.81354  ? 303 ILE B C   1 
ATOM   4668 O O   . ILE B 1 343 ? 42.27005  -25.25511 36.47185  1.000 60.38951  ? 303 ILE B O   1 
ATOM   4669 C CB  . ILE B 1 343 ? 39.36617  -23.66907 36.21696  1.000 52.28124  ? 303 ILE B CB  1 
ATOM   4670 C CG1 . ILE B 1 343 ? 37.97508  -23.90717 35.62507  1.000 55.68804  ? 303 ILE B CG1 1 
ATOM   4671 C CG2 . ILE B 1 343 ? 40.30911  -23.15239 35.14208  1.000 47.99258  ? 303 ILE B CG2 1 
ATOM   4672 C CD1 . ILE B 1 343 ? 37.28291  -22.64917 35.15753  1.000 53.71111  ? 303 ILE B CD1 1 
ATOM   4673 N N   . ARG B 1 344 ? 41.65922  -24.26770 38.39780  1.000 53.65644  ? 304 ARG B N   1 
ATOM   4674 C CA  . ARG B 1 344 ? 43.04298  -24.15208 38.84656  1.000 61.35405  ? 304 ARG B CA  1 
ATOM   4675 C C   . ARG B 1 344 ? 43.68553  -25.52006 39.05271  1.000 60.39292  ? 304 ARG B C   1 
ATOM   4676 O O   . ARG B 1 344 ? 44.85872  -25.71866 38.71500  1.000 65.26235  ? 304 ARG B O   1 
ATOM   4677 C CB  . ARG B 1 344 ? 43.10620  -23.34945 40.14522  1.000 59.88413  ? 304 ARG B CB  1 
ATOM   4678 C CG  . ARG B 1 344 ? 44.51199  -23.20003 40.70269  1.000 77.81580  ? 304 ARG B CG  1 
ATOM   4679 C CD  . ARG B 1 344 ? 44.51953  -22.37871 41.97859  1.000 78.36695  ? 304 ARG B CD  1 
ATOM   4680 N NE  . ARG B 1 344 ? 43.96354  -21.04671 41.77903  1.000 90.29483  ? 304 ARG B NE  1 
ATOM   4681 C CZ  . ARG B 1 344 ? 42.79830  -20.64741 42.27002  1.000 93.47966  ? 304 ARG B CZ  1 
ATOM   4682 N NH1 . ARG B 1 344 ? 42.04392  -21.45339 42.99922  1.000 91.43367  ? 304 ARG B NH1 1 
ATOM   4683 N NH2 . ARG B 1 344 ? 42.37763  -19.41060 42.02100  1.000 72.88454  ? 304 ARG B NH2 1 
ATOM   4684 N N   . ARG B 1 345 ? 42.93423  -26.48073 39.59611  1.000 63.06408  ? 305 ARG B N   1 
ATOM   4685 C CA  . ARG B 1 345 ? 43.52708  -27.76848 39.93918  1.000 56.27473  ? 305 ARG B CA  1 
ATOM   4686 C C   . ARG B 1 345 ? 43.57978  -28.72877 38.75498  1.000 55.46331  ? 305 ARG B C   1 
ATOM   4687 O O   . ARG B 1 345 ? 44.42500  -29.63084 38.74468  1.000 63.83090  ? 305 ARG B O   1 
ATOM   4688 C CB  . ARG B 1 345 ? 42.79229  -28.38713 41.13907  1.000 49.83559  ? 305 ARG B CB  1 
ATOM   4689 C CG  . ARG B 1 345 ? 43.52652  -29.57517 41.76254  1.000 71.70306  ? 305 ARG B CG  1 
ATOM   4690 C CD  . ARG B 1 345 ? 42.66899  -30.44041 42.68448  1.000 93.42671  ? 305 ARG B CD  1 
ATOM   4691 N NE  . ARG B 1 345 ? 41.52958  -31.09138 42.05249  1.000 74.69976  ? 305 ARG B NE  1 
ATOM   4692 C CZ  . ARG B 1 345 ? 40.26748  -30.77447 42.30020  1.000 76.46532  ? 305 ARG B CZ  1 
ATOM   4693 N NH1 . ARG B 1 345 ? 39.95277  -29.80716 43.14683  1.000 79.49438  ? 305 ARG B NH1 1 
ATOM   4694 N NH2 . ARG B 1 345 ? 39.29798  -31.46227 41.70544  1.000 71.30570  ? 305 ARG B NH2 1 
ATOM   4695 N N   . LEU B 1 346 ? 42.71795  -28.55640 37.75539  1.000 48.77632  ? 306 LEU B N   1 
ATOM   4696 C CA  . LEU B 1 346 ? 42.54360  -29.57050 36.72527  1.000 54.47513  ? 306 LEU B CA  1 
ATOM   4697 C C   . LEU B 1 346 ? 42.91688  -29.11429 35.32136  1.000 56.38381  ? 306 LEU B C   1 
ATOM   4698 O O   . LEU B 1 346 ? 43.35912  -29.94476 34.52422  1.000 51.30504  ? 306 LEU B O   1 
ATOM   4699 C CB  . LEU B 1 346 ? 41.08972  -30.06581 36.71136  1.000 58.02656  ? 306 LEU B CB  1 
ATOM   4700 C CG  . LEU B 1 346 ? 40.67162  -30.84725 37.95636  1.000 59.54199  ? 306 LEU B CG  1 
ATOM   4701 C CD1 . LEU B 1 346 ? 39.17391  -31.09077 37.95280  1.000 50.93989  ? 306 LEU B CD1 1 
ATOM   4702 C CD2 . LEU B 1 346 ? 41.43809  -32.15805 38.05081  1.000 42.75167  ? 306 LEU B CD2 1 
ATOM   4703 N N   . VAL B 1 347 ? 42.76057  -27.83474 34.99353  1.000 52.95602  ? 307 VAL B N   1 
ATOM   4704 C CA  . VAL B 1 347 ? 43.04439  -27.36397 33.63954  1.000 53.15104  ? 307 VAL B CA  1 
ATOM   4705 C C   . VAL B 1 347 ? 44.52429  -27.04211 33.48754  1.000 74.87189  ? 307 VAL B C   1 
ATOM   4706 O O   . VAL B 1 347 ? 45.21998  -27.61687 32.64805  1.000 76.10114  ? 307 VAL B O   1 
ATOM   4707 C CB  . VAL B 1 347 ? 42.18955  -26.13733 33.27768  1.000 53.17031  ? 307 VAL B CB  1 
ATOM   4708 C CG1 . VAL B 1 347 ? 42.58718  -25.59881 31.90983  1.000 50.60539  ? 307 VAL B CG1 1 
ATOM   4709 C CG2 . VAL B 1 347 ? 40.71029  -26.49171 33.30938  1.000 54.52801  ? 307 VAL B CG2 1 
ATOM   4710 O OXT . VAL B 1 347 ? 45.05355  -26.19248 34.20495  1.000 75.75438  ? 307 VAL B OXT 1 
ATOM   4711 N N   . SER C 1 42  ? 11.26135  -51.41138 20.60123  1.000 88.49793  ? 2   SER C N   1 
ATOM   4712 C CA  . SER C 1 42  ? 11.77308  -52.71607 21.00596  1.000 105.20627 ? 2   SER C CA  1 
ATOM   4713 C C   . SER C 1 42  ? 10.87914  -53.33647 22.07554  1.000 99.01877  ? 2   SER C C   1 
ATOM   4714 O O   . SER C 1 42  ? 9.66184   -53.14589 22.06733  1.000 83.33494  ? 2   SER C O   1 
ATOM   4715 C CB  . SER C 1 42  ? 13.21065  -52.58966 21.51979  1.000 100.69036 ? 2   SER C CB  1 
ATOM   4716 O OG  . SER C 1 42  ? 13.77836  -53.85995 21.78977  1.000 95.03135  ? 2   SER C OG  1 
ATOM   4717 N N   . GLU C 1 43  ? 11.48843  -54.08820 22.99044  1.000 92.67363  ? 3   GLU C N   1 
ATOM   4718 C CA  . GLU C 1 43  ? 10.78171  -54.61806 24.14868  1.000 91.69761  ? 3   GLU C CA  1 
ATOM   4719 C C   . GLU C 1 43  ? 10.65006  -53.59613 25.26655  1.000 90.16613  ? 3   GLU C C   1 
ATOM   4720 O O   . GLU C 1 43  ? 10.24486  -53.96432 26.37464  1.000 85.27803  ? 3   GLU C O   1 
ATOM   4721 C CB  . GLU C 1 43  ? 11.49345  -55.86043 24.68706  1.000 98.91743  ? 3   GLU C CB  1 
ATOM   4722 C CG  . GLU C 1 43  ? 11.98223  -56.82081 23.62552  1.000 101.56415 ? 3   GLU C CG  1 
ATOM   4723 C CD  . GLU C 1 43  ? 12.85028  -57.91604 24.20793  1.000 114.11499 ? 3   GLU C CD  1 
ATOM   4724 O OE1 . GLU C 1 43  ? 12.54897  -58.38186 25.32676  1.000 113.85472 ? 3   GLU C OE1 1 
ATOM   4725 O OE2 . GLU C 1 43  ? 13.84050  -58.30196 23.55372  1.000 120.82398 ? 3   GLU C OE2 1 
ATOM   4726 N N   . ILE C 1 44  ? 11.00459  -52.33720 25.00264  1.000 78.06842  ? 4   ILE C N   1 
ATOM   4727 C CA  . ILE C 1 44  ? 10.94996  -51.29793 26.02351  1.000 75.76903  ? 4   ILE C CA  1 
ATOM   4728 C C   . ILE C 1 44  ? 9.52498   -51.18517 26.53885  1.000 63.61372  ? 4   ILE C C   1 
ATOM   4729 O O   . ILE C 1 44  ? 8.58389   -50.97804 25.76259  1.000 70.97488  ? 4   ILE C O   1 
ATOM   4730 C CB  . ILE C 1 44  ? 11.45279  -49.96472 25.46042  1.000 79.52025  ? 4   ILE C CB  1 
ATOM   4731 C CG1 . ILE C 1 44  ? 12.91426  -50.08978 25.02265  1.000 79.47931  ? 4   ILE C CG1 1 
ATOM   4732 C CG2 . ILE C 1 44  ? 11.27736  -48.84825 26.48328  1.000 59.17954  ? 4   ILE C CG2 1 
ATOM   4733 C CD1 . ILE C 1 44  ? 13.43710  -48.87823 24.28884  1.000 79.36035  ? 4   ILE C CD1 1 
ATOM   4734 N N   . ARG C 1 45  ? 9.36070   -51.33774 27.85177  1.000 64.37811  ? 5   ARG C N   1 
ATOM   4735 C CA  . ARG C 1 45  ? 8.03964   -51.25849 28.45694  1.000 66.05353  ? 5   ARG C CA  1 
ATOM   4736 C C   . ARG C 1 45  ? 7.40678   -49.91070 28.14030  1.000 75.59356  ? 5   ARG C C   1 
ATOM   4737 O O   . ARG C 1 45  ? 8.06279   -48.86576 28.20823  1.000 68.88311  ? 5   ARG C O   1 
ATOM   4738 C CB  . ARG C 1 45  ? 8.13069   -51.43872 29.97447  1.000 69.47570  ? 5   ARG C CB  1 
ATOM   4739 C CG  . ARG C 1 45  ? 6.78137   -51.56616 30.66953  1.000 79.95167  ? 5   ARG C CG  1 
ATOM   4740 C CD  . ARG C 1 45  ? 6.92729   -52.22870 32.03262  1.000 93.80129  ? 5   ARG C CD  1 
ATOM   4741 N NE  . ARG C 1 45  ? 7.38563   -53.61209 31.96926  1.000 98.76782  ? 5   ARG C NE  1 
ATOM   4742 C CZ  . ARG C 1 45  ? 6.59521   -54.67540 31.91944  1.000 93.27960  ? 5   ARG C CZ  1 
ATOM   4743 N NH1 . ARG C 1 45  ? 5.27758   -54.56012 31.93360  1.000 89.31380  ? 5   ARG C NH1 1 
ATOM   4744 N NH2 . ARG C 1 45  ? 7.14232   -55.88720 31.87631  1.000 99.29473  ? 5   ARG C NH2 1 
ATOM   4745 N N   . THR C 1 46  ? 6.12454   -49.93409 27.79385  1.000 80.35137  ? 6   THR C N   1 
ATOM   4746 C CA  . THR C 1 46  ? 5.43357   -48.67350 27.60638  1.000 68.71215  ? 6   THR C CA  1 
ATOM   4747 C C   . THR C 1 46  ? 4.94025   -48.15090 28.95056  1.000 60.87029  ? 6   THR C C   1 
ATOM   4748 O O   . THR C 1 46  ? 4.78475   -48.89590 29.92307  1.000 64.26828  ? 6   THR C O   1 
ATOM   4749 C CB  . THR C 1 46  ? 4.26446   -48.82395 26.63510  1.000 74.40768  ? 6   THR C CB  1 
ATOM   4750 O OG1 . THR C 1 46  ? 3.63171   -47.55235 26.45093  1.000 77.32061  ? 6   THR C OG1 1 
ATOM   4751 C CG2 . THR C 1 46  ? 3.24601   -49.82232 27.17131  1.000 71.44748  ? 6   THR C CG2 1 
ATOM   4752 N N   . GLU C 1 47  ? 4.70474   -46.84483 28.99731  1.000 68.78620  ? 7   GLU C N   1 
ATOM   4753 C CA  . GLU C 1 47  ? 4.33214   -46.19946 30.24334  1.000 73.39312  ? 7   GLU C CA  1 
ATOM   4754 C C   . GLU C 1 47  ? 2.97183   -46.71817 30.72050  1.000 69.31876  ? 7   GLU C C   1 
ATOM   4755 O O   . GLU C 1 47  ? 2.21678   -47.35513 29.97963  1.000 72.25649  ? 7   GLU C O   1 
ATOM   4756 C CB  . GLU C 1 47  ? 4.36024   -44.67924 30.06485  1.000 72.79721  ? 7   GLU C CB  1 
ATOM   4757 C CG  . GLU C 1 47  ? 4.56018   -43.88343 31.34914  1.000 74.55388  ? 7   GLU C CG  1 
ATOM   4758 C CD  . GLU C 1 47  ? 4.59043   -42.38647 31.09892  1.000 77.75523  ? 7   GLU C CD  1 
ATOM   4759 O OE1 . GLU C 1 47  ? 4.48946   -41.97622 29.92185  1.000 78.01459  ? 7   GLU C OE1 1 
ATOM   4760 O OE2 . GLU C 1 47  ? 4.74031   -41.62174 32.07425  1.000 87.27204  ? 7   GLU C OE2 1 
ATOM   4761 N N   . ARG C 1 48  ? 2.65812   -46.41987 31.97111  1.000 69.46503  ? 8   ARG C N   1 
ATOM   4762 C CA  . ARG C 1 48  ? 1.45808   -46.95002 32.61715  1.000 71.56060  ? 8   ARG C CA  1 
ATOM   4763 C C   . ARG C 1 48  ? 0.25372   -46.06680 32.30838  1.000 72.02852  ? 8   ARG C C   1 
ATOM   4764 O O   . ARG C 1 48  ? 0.36061   -44.83701 32.37224  1.000 77.09513  ? 8   ARG C O   1 
ATOM   4765 C CB  . ARG C 1 48  ? 1.66823   -47.07927 34.12693  1.000 74.49901  ? 8   ARG C CB  1 
ATOM   4766 C CG  . ARG C 1 48  ? 1.97293   -45.77911 34.84764  1.000 90.23601  ? 8   ARG C CG  1 
ATOM   4767 C CD  . ARG C 1 48  ? 2.08991   -45.98930 36.34736  1.000 103.08492 ? 8   ARG C CD  1 
ATOM   4768 N NE  . ARG C 1 48  ? 2.43023   -44.75176 37.03804  1.000 119.81574 ? 8   ARG C NE  1 
ATOM   4769 C CZ  . ARG C 1 48  ? 1.55677   -43.81073 37.36520  1.000 118.36069 ? 8   ARG C CZ  1 
ATOM   4770 N NH1 . ARG C 1 48  ? 0.27413   -43.92572 37.06452  1.000 88.19747  ? 8   ARG C NH1 1 
ATOM   4771 N NH2 . ARG C 1 48  ? 1.98340   -42.72113 37.99793  1.000 114.80515 ? 8   ARG C NH2 1 
ATOM   4772 N N   . PRO C 1 49  ? -0.88557  -46.65251 31.93343  1.000 68.51970  ? 9   PRO C N   1 
ATOM   4773 C CA  . PRO C 1 49  ? -2.02852  -45.84048 31.49986  1.000 64.63840  ? 9   PRO C CA  1 
ATOM   4774 C C   . PRO C 1 49  ? -2.53365  -44.90885 32.59166  1.000 57.46932  ? 9   PRO C C   1 
ATOM   4775 O O   . PRO C 1 49  ? -2.38087  -45.16364 33.78917  1.000 58.25774  ? 9   PRO C O   1 
ATOM   4776 C CB  . PRO C 1 49  ? -3.08694  -46.88944 31.13667  1.000 62.79234  ? 9   PRO C CB  1 
ATOM   4777 C CG  . PRO C 1 49  ? -2.74089  -48.06586 31.99593  1.000 55.09724  ? 9   PRO C CG  1 
ATOM   4778 C CD  . PRO C 1 49  ? -1.23509  -48.07960 32.05330  1.000 60.17056  ? 9   PRO C CD  1 
ATOM   4779 N N   . ILE C 1 50  ? -3.14792  -43.81159 32.14991  1.000 56.75176  ? 10  ILE C N   1 
ATOM   4780 C CA  . ILE C 1 50  ? -3.73785  -42.84766 33.06782  1.000 58.54021  ? 10  ILE C CA  1 
ATOM   4781 C C   . ILE C 1 50  ? -5.00299  -43.44005 33.67172  1.000 58.19887  ? 10  ILE C C   1 
ATOM   4782 O O   . ILE C 1 50  ? -5.88449  -43.92992 32.95321  1.000 55.16649  ? 10  ILE C O   1 
ATOM   4783 C CB  . ILE C 1 50  ? -4.03276  -41.52928 32.33757  1.000 55.45322  ? 10  ILE C CB  1 
ATOM   4784 C CG1 . ILE C 1 50  ? -2.80997  -41.07659 31.53626  1.000 56.91830  ? 10  ILE C CG1 1 
ATOM   4785 C CG2 . ILE C 1 50  ? -4.45669  -40.45311 33.32567  1.000 51.58435  ? 10  ILE C CG2 1 
ATOM   4786 C CD1 . ILE C 1 50  ? -3.09946  -39.95304 30.56271  1.000 53.62221  ? 10  ILE C CD1 1 
ATOM   4787 N N   . ARG C 1 51  ? -5.09662  -43.40577 34.99773  1.000 55.56123  ? 11  ARG C N   1 
ATOM   4788 C CA  . ARG C 1 51  ? -6.25864  -43.93202 35.70118  1.000 61.93329  ? 11  ARG C CA  1 
ATOM   4789 C C   . ARG C 1 51  ? -7.26137  -42.80357 35.91036  1.000 57.20245  ? 11  ARG C C   1 
ATOM   4790 O O   . ARG C 1 51  ? -6.97397  -41.82983 36.61585  1.000 63.12932  ? 11  ARG C O   1 
ATOM   4791 C CB  . ARG C 1 51  ? -5.84742  -44.56606 37.02876  1.000 60.19871  ? 11  ARG C CB  1 
ATOM   4792 C CG  . ARG C 1 51  ? -4.83489  -45.69273 36.86646  1.000 55.66415  ? 11  ARG C CG  1 
ATOM   4793 C CD  . ARG C 1 51  ? -4.89686  -46.66391 38.02687  1.000 58.67620  ? 11  ARG C CD  1 
ATOM   4794 N NE  . ARG C 1 51  ? -5.98679  -47.61336 37.84392  1.000 66.28813  ? 11  ARG C NE  1 
ATOM   4795 C CZ  . ARG C 1 51  ? -7.02683  -47.72545 38.65733  1.000 60.03627  ? 11  ARG C CZ  1 
ATOM   4796 N NH1 . ARG C 1 51  ? -7.14800  -46.96545 39.73380  1.000 64.82451  ? 11  ARG C NH1 1 
ATOM   4797 N NH2 . ARG C 1 51  ? -7.97226  -48.61768 38.38009  1.000 68.14463  ? 11  ARG C NH2 1 
ATOM   4798 N N   . VAL C 1 52  ? -8.43251  -42.93601 35.29404  1.000 56.50813  ? 12  VAL C N   1 
ATOM   4799 C CA  . VAL C 1 52  ? -9.43381  -41.87762 35.24781  1.000 60.23218  ? 12  VAL C CA  1 
ATOM   4800 C C   . VAL C 1 52  ? -10.65703 -42.31092 36.04330  1.000 62.97277  ? 12  VAL C C   1 
ATOM   4801 O O   . VAL C 1 52  ? -11.14862 -43.43531 35.88171  1.000 61.35242  ? 12  VAL C O   1 
ATOM   4802 C CB  . VAL C 1 52  ? -9.81639  -41.53536 33.79682  1.000 60.51701  ? 12  VAL C CB  1 
ATOM   4803 C CG1 . VAL C 1 52  ? -10.95507 -40.52068 33.76833  1.000 47.55657  ? 12  VAL C CG1 1 
ATOM   4804 C CG2 . VAL C 1 52  ? -8.59799  -41.01709 33.02927  1.000 49.56923  ? 12  VAL C CG2 1 
ATOM   4805 N N   . ALA C 1 53  ? -11.14184 -41.41978 36.90316  1.000 61.58659  ? 13  ALA C N   1 
ATOM   4806 C CA  . ALA C 1 53  ? -12.40019 -41.59762 37.61146  1.000 66.11383  ? 13  ALA C CA  1 
ATOM   4807 C C   . ALA C 1 53  ? -13.43013 -40.62484 37.05154  1.000 63.89718  ? 13  ALA C C   1 
ATOM   4808 O O   . ALA C 1 53  ? -13.10688 -39.47000 36.75329  1.000 55.79840  ? 13  ALA C O   1 
ATOM   4809 C CB  . ALA C 1 53  ? -12.22534 -41.37455 39.11498  1.000 55.19836  ? 13  ALA C CB  1 
ATOM   4810 N N   . ILE C 1 54  ? -14.66646 -41.09332 36.90547  1.000 56.47975  ? 14  ILE C N   1 
ATOM   4811 C CA  . ILE C 1 54  ? -15.76157 -40.28305 36.38313  1.000 58.47481  ? 14  ILE C CA  1 
ATOM   4812 C C   . ILE C 1 54  ? -16.63811 -39.83891 37.54650  1.000 58.62360  ? 14  ILE C C   1 
ATOM   4813 O O   . ILE C 1 54  ? -17.18261 -40.67185 38.28110  1.000 66.90628  ? 14  ILE C O   1 
ATOM   4814 C CB  . ILE C 1 54  ? -16.57675 -41.05198 35.33208  1.000 64.41231  ? 14  ILE C CB  1 
ATOM   4815 C CG1 . ILE C 1 54  ? -15.70113 -41.37903 34.11929  1.000 54.14647  ? 14  ILE C CG1 1 
ATOM   4816 C CG2 . ILE C 1 54  ? -17.80550 -40.24981 34.91095  1.000 53.95234  ? 14  ILE C CG2 1 
ATOM   4817 C CD1 . ILE C 1 54  ? -16.35944 -42.30223 33.12191  1.000 55.40601  ? 14  ILE C CD1 1 
ATOM   4818 N N   . ILE C 1 55  ? -16.77006 -38.52773 37.71424  1.000 57.24925  ? 15  ILE C N   1 
ATOM   4819 C CA  . ILE C 1 55  ? -17.52984 -37.93205 38.80735  1.000 62.93644  ? 15  ILE C CA  1 
ATOM   4820 C C   . ILE C 1 55  ? -18.88055 -37.49177 38.25406  1.000 63.95474  ? 15  ILE C C   1 
ATOM   4821 O O   . ILE C 1 55  ? -18.96023 -36.52771 37.48485  1.000 70.13135  ? 15  ILE C O   1 
ATOM   4822 C CB  . ILE C 1 55  ? -16.77789 -36.75050 39.43523  1.000 68.20363  ? 15  ILE C CB  1 
ATOM   4823 C CG1 . ILE C 1 55  ? -15.29474 -37.08684 39.61609  1.000 54.53753  ? 15  ILE C CG1 1 
ATOM   4824 C CG2 . ILE C 1 55  ? -17.40431 -36.36798 40.76556  1.000 61.72189  ? 15  ILE C CG2 1 
ATOM   4825 C CD1 . ILE C 1 55  ? -15.03807 -38.25209 40.53832  1.000 56.56983  ? 15  ILE C CD1 1 
ATOM   4826 N N   . GLY C 1 56  ? -19.94781 -38.18707 38.64528  1.000 66.09915  ? 16  GLY C N   1 
ATOM   4827 C CA  . GLY C 1 56  ? -21.28447 -37.84406 38.19058  1.000 65.25028  ? 16  GLY C CA  1 
ATOM   4828 C C   . GLY C 1 56  ? -21.68256 -38.57302 36.92327  1.000 67.96106  ? 16  GLY C C   1 
ATOM   4829 O O   . GLY C 1 56  ? -21.03817 -38.41211 35.88302  1.000 72.84508  ? 16  GLY C O   1 
ATOM   4830 N N   . TYR C 1 57  ? -22.73670 -39.38273 36.99362  1.000 76.25130  ? 17  TYR C N   1 
ATOM   4831 C CA  . TYR C 1 57  ? -23.13815 -40.25321 35.88956  1.000 67.83852  ? 17  TYR C CA  1 
ATOM   4832 C C   . TYR C 1 57  ? -24.44590 -39.76221 35.26784  1.000 73.27413  ? 17  TYR C C   1 
ATOM   4833 O O   . TYR C 1 57  ? -25.51411 -40.33632 35.48398  1.000 83.00781  ? 17  TYR C O   1 
ATOM   4834 C CB  . TYR C 1 57  ? -23.25777 -41.70060 36.36497  1.000 59.81228  ? 17  TYR C CB  1 
ATOM   4835 C CG  . TYR C 1 57  ? -23.17597 -42.69804 35.23370  1.000 69.16004  ? 17  TYR C CG  1 
ATOM   4836 C CD1 . TYR C 1 57  ? -21.99072 -42.87867 34.53209  1.000 64.90636  ? 17  TYR C CD1 1 
ATOM   4837 C CD2 . TYR C 1 57  ? -24.28126 -43.44865 34.85578  1.000 68.82121  ? 17  TYR C CD2 1 
ATOM   4838 C CE1 . TYR C 1 57  ? -21.90475 -43.78331 33.49250  1.000 64.76687  ? 17  TYR C CE1 1 
ATOM   4839 C CE2 . TYR C 1 57  ? -24.20457 -44.35822 33.81419  1.000 71.41169  ? 17  TYR C CE2 1 
ATOM   4840 C CZ  . TYR C 1 57  ? -23.01311 -44.52001 33.13747  1.000 74.39686  ? 17  TYR C CZ  1 
ATOM   4841 O OH  . TYR C 1 57  ? -22.92752 -45.41975 32.10173  1.000 66.86463  ? 17  TYR C OH  1 
ATOM   4842 N N   . GLY C 1 58  ? -24.35812 -38.68870 34.49436  1.000 76.78681  ? 18  GLY C N   1 
ATOM   4843 C CA  . GLY C 1 58  ? -25.45833 -38.23432 33.66140  1.000 67.41513  ? 18  GLY C CA  1 
ATOM   4844 C C   . GLY C 1 58  ? -25.26297 -38.66097 32.22128  1.000 69.18510  ? 18  GLY C C   1 
ATOM   4845 O O   . GLY C 1 58  ? -24.64202 -39.69186 31.93762  1.000 71.99148  ? 18  GLY C O   1 
ATOM   4846 N N   . ASN C 1 59  ? -25.79276 -37.86096 31.28851  1.000 66.44030  ? 19  ASN C N   1 
ATOM   4847 C CA  . ASN C 1 59  ? -25.52975 -38.14188 29.87783  1.000 76.47446  ? 19  ASN C CA  1 
ATOM   4848 C C   . ASN C 1 59  ? -24.04629 -37.98382 29.57079  1.000 70.26974  ? 19  ASN C C   1 
ATOM   4849 O O   . ASN C 1 59  ? -23.45418 -38.83207 28.89380  1.000 77.82888  ? 19  ASN C O   1 
ATOM   4850 C CB  . ASN C 1 59  ? -26.37141 -37.25196 28.95907  1.000 67.25113  ? 19  ASN C CB  1 
ATOM   4851 C CG  . ASN C 1 59  ? -27.22599 -36.27412 29.71617  1.000 76.13213  ? 19  ASN C CG  1 
ATOM   4852 O OD1 . ASN C 1 59  ? -26.81698 -35.76155 30.74737  1.000 84.54256  ? 19  ASN C OD1 1 
ATOM   4853 N ND2 . ASN C 1 59  ? -28.42570 -36.01029 29.20925  1.000 85.01286  ? 19  ASN C ND2 1 
ATOM   4854 N N   . ILE C 1 60  ? -23.43295 -36.89939 30.05806  1.000 66.29088  ? 20  ILE C N   1 
ATOM   4855 C CA  . ILE C 1 60  ? -22.00214 -36.68790 29.85017  1.000 70.74514  ? 20  ILE C CA  1 
ATOM   4856 C C   . ILE C 1 60  ? -21.20757 -37.84153 30.44641  1.000 64.17790  ? 20  ILE C C   1 
ATOM   4857 O O   . ILE C 1 60  ? -20.23497 -38.31923 29.85030  1.000 59.39127  ? 20  ILE C O   1 
ATOM   4858 C CB  . ILE C 1 60  ? -21.56415 -35.33835 30.45282  1.000 65.93182  ? 20  ILE C CB  1 
ATOM   4859 C CG1 . ILE C 1 60  ? -22.26369 -34.17027 29.75652  1.000 59.42024  ? 20  ILE C CG1 1 
ATOM   4860 C CG2 . ILE C 1 60  ? -20.05259 -35.18055 30.37715  1.000 52.50685  ? 20  ILE C CG2 1 
ATOM   4861 C CD1 . ILE C 1 60  ? -21.88857 -34.01329 28.31034  1.000 51.33312  ? 20  ILE C CD1 1 
ATOM   4862 N N   . GLY C 1 61  ? -21.60693 -38.30604 31.63119  1.000 68.24132  ? 21  GLY C N   1 
ATOM   4863 C CA  . GLY C 1 61  ? -20.89724 -39.40869 32.25787  1.000 66.88383  ? 21  GLY C CA  1 
ATOM   4864 C C   . GLY C 1 61  ? -20.99269 -40.69249 31.45570  1.000 64.92446  ? 21  GLY C C   1 
ATOM   4865 O O   . GLY C 1 61  ? -20.03273 -41.46369 31.38393  1.000 62.06775  ? 21  GLY C O   1 
ATOM   4866 N N   . GLN C 1 62  ? -22.15787 -40.94493 30.85195  1.000 63.69442  ? 22  GLN C N   1 
ATOM   4867 C CA  . GLN C 1 62  ? -22.32757 -42.13996 30.03072  1.000 68.01987  ? 22  GLN C CA  1 
ATOM   4868 C C   . GLN C 1 62  ? -21.41601 -42.10372 28.81162  1.000 64.41333  ? 22  GLN C C   1 
ATOM   4869 O O   . GLN C 1 62  ? -20.79527 -43.11326 28.45861  1.000 67.88333  ? 22  GLN C O   1 
ATOM   4870 C CB  . GLN C 1 62  ? -23.78700 -42.27439 29.59733  1.000 64.06190  ? 22  GLN C CB  1 
ATOM   4871 C CG  . GLN C 1 62  ? -24.75956 -42.55233 30.73080  1.000 78.69236  ? 22  GLN C CG  1 
ATOM   4872 C CD  . GLN C 1 62  ? -26.18845 -42.19511 30.36483  1.000 78.65623  ? 22  GLN C CD  1 
ATOM   4873 O OE1 . GLN C 1 62  ? -26.51251 -42.00619 29.19166  1.000 81.67000  ? 22  GLN C OE1 1 
ATOM   4874 N NE2 . GLN C 1 62  ? -27.05056 -42.09877 31.36980  1.000 76.75798  ? 22  GLN C NE2 1 
ATOM   4875 N N   . TYR C 1 63  ? -21.32913 -40.94916 28.14885  1.000 56.83873  ? 23  TYR C N   1 
ATOM   4876 C CA  . TYR C 1 63  ? -20.45495 -40.83436 26.98736  1.000 56.93604  ? 23  TYR C CA  1 
ATOM   4877 C C   . TYR C 1 63  ? -18.98943 -40.78860 27.40133  1.000 58.36434  ? 23  TYR C C   1 
ATOM   4878 O O   . TYR C 1 63  ? -18.12233 -41.31053 26.69032  1.000 52.27758  ? 23  TYR C O   1 
ATOM   4879 C CB  . TYR C 1 63  ? -20.82617 -39.59894 26.17018  1.000 53.07898  ? 23  TYR C CB  1 
ATOM   4880 C CG  . TYR C 1 63  ? -22.09271 -39.74456 25.36014  1.000 41.67047  ? 23  TYR C CG  1 
ATOM   4881 C CD1 . TYR C 1 63  ? -22.05911 -40.26475 24.07358  1.000 37.68895  ? 23  TYR C CD1 1 
ATOM   4882 C CD2 . TYR C 1 63  ? -23.32022 -39.35357 25.87544  1.000 57.53840  ? 23  TYR C CD2 1 
ATOM   4883 C CE1 . TYR C 1 63  ? -23.21278 -40.39359 23.32186  1.000 50.27565  ? 23  TYR C CE1 1 
ATOM   4884 C CE2 . TYR C 1 63  ? -24.47984 -39.47874 25.13315  1.000 46.97019  ? 23  TYR C CE2 1 
ATOM   4885 C CZ  . TYR C 1 63  ? -24.42080 -39.99856 23.85705  1.000 46.08491  ? 23  TYR C CZ  1 
ATOM   4886 O OH  . TYR C 1 63  ? -25.57476 -40.12376 23.11833  1.000 46.15680  ? 23  TYR C OH  1 
ATOM   4887 N N   . ALA C 1 64  ? -18.69140 -40.14515 28.53376  1.000 59.57108  ? 24  ALA C N   1 
ATOM   4888 C CA  . ALA C 1 64  ? -17.32407 -40.13916 29.04382  1.000 52.50920  ? 24  ALA C CA  1 
ATOM   4889 C C   . ALA C 1 64  ? -16.82074 -41.55680 29.28127  1.000 57.49588  ? 24  ALA C C   1 
ATOM   4890 O O   . ALA C 1 64  ? -15.63962 -41.85017 29.05929  1.000 58.15679  ? 24  ALA C O   1 
ATOM   4891 C CB  . ALA C 1 64  ? -17.24300 -39.31472 30.32905  1.000 42.89413  ? 24  ALA C CB  1 
ATOM   4892 N N   . LEU C 1 65  ? -17.70271 -42.44496 29.74666  1.000 55.92358  ? 25  LEU C N   1 
ATOM   4893 C CA  . LEU C 1 65  ? -17.33780 -43.84744 29.91983  1.000 50.47962  ? 25  LEU C CA  1 
ATOM   4894 C C   . LEU C 1 65  ? -16.80338 -44.43853 28.62048  1.000 54.30498  ? 25  LEU C C   1 
ATOM   4895 O O   . LEU C 1 65  ? -15.76909 -45.11651 28.60904  1.000 54.49706  ? 25  LEU C O   1 
ATOM   4896 C CB  . LEU C 1 65  ? -18.54638 -44.64281 30.41283  1.000 53.94220  ? 25  LEU C CB  1 
ATOM   4897 C CG  . LEU C 1 65  ? -18.26241 -46.07626 30.85832  1.000 55.75048  ? 25  LEU C CG  1 
ATOM   4898 C CD1 . LEU C 1 65  ? -18.00754 -46.11826 32.35764  1.000 57.90912  ? 25  LEU C CD1 1 
ATOM   4899 C CD2 . LEU C 1 65  ? -19.39549 -47.01307 30.47097  1.000 68.91950  ? 25  LEU C CD2 1 
ATOM   4900 N N   . GLN C 1 66  ? -17.50206 -44.18800 27.51087  1.000 53.44696  ? 26  GLN C N   1 
ATOM   4901 C CA  . GLN C 1 66  ? -17.07240 -44.71707 26.22061  1.000 57.86767  ? 26  GLN C CA  1 
ATOM   4902 C C   . GLN C 1 66  ? -15.76871 -44.07447 25.76584  1.000 61.44600  ? 26  GLN C C   1 
ATOM   4903 O O   . GLN C 1 66  ? -14.90520 -44.74646 25.18976  1.000 59.84050  ? 26  GLN C O   1 
ATOM   4904 C CB  . GLN C 1 66  ? -18.16678 -44.49046 25.17898  1.000 59.42093  ? 26  GLN C CB  1 
ATOM   4905 C CG  . GLN C 1 66  ? -19.53315 -45.01197 25.58892  1.000 53.81942  ? 26  GLN C CG  1 
ATOM   4906 C CD  . GLN C 1 66  ? -20.62642 -44.60528 24.61902  1.000 62.86455  ? 26  GLN C CD  1 
ATOM   4907 O OE1 . GLN C 1 66  ? -20.49066 -43.62153 23.89057  1.000 69.63488  ? 26  GLN C OE1 1 
ATOM   4908 N NE2 . GLN C 1 66  ? -21.71999 -45.35798 24.60895  1.000 61.22830  ? 26  GLN C NE2 1 
ATOM   4909 N N   . ALA C 1 67  ? -15.61619 -42.77017 26.00357  1.000 55.95497  ? 27  ALA C N   1 
ATOM   4910 C CA  . ALA C 1 67  ? -14.39930 -42.07659 25.59563  1.000 48.15792  ? 27  ALA C CA  1 
ATOM   4911 C C   . ALA C 1 67  ? -13.18452 -42.60773 26.34519  1.000 57.71620  ? 27  ALA C C   1 
ATOM   4912 O O   . ALA C 1 67  ? -12.09861 -42.74062 25.76712  1.000 56.74616  ? 27  ALA C O   1 
ATOM   4913 C CB  . ALA C 1 67  ? -14.55568 -40.57264 25.81352  1.000 42.51152  ? 27  ALA C CB  1 
ATOM   4914 N N   . VAL C 1 68  ? -13.34392 -42.89972 27.63937  1.000 52.70259  ? 28  VAL C N   1 
ATOM   4915 C CA  . VAL C 1 68  ? -12.24097 -43.45680 28.41861  1.000 55.67256  ? 28  VAL C CA  1 
ATOM   4916 C C   . VAL C 1 68  ? -11.84557 -44.82903 27.88731  1.000 48.67163  ? 28  VAL C C   1 
ATOM   4917 O O   . VAL C 1 68  ? -10.65524 -45.13451 27.74664  1.000 59.34595  ? 28  VAL C O   1 
ATOM   4918 C CB  . VAL C 1 68  ? -12.61763 -43.51461 29.91123  1.000 54.60346  ? 28  VAL C CB  1 
ATOM   4919 C CG1 . VAL C 1 68  ? -11.57733 -44.30648 30.69938  1.000 41.32674  ? 28  VAL C CG1 1 
ATOM   4920 C CG2 . VAL C 1 68  ? -12.76411 -42.10777 30.48024  1.000 49.40765  ? 28  VAL C CG2 1 
ATOM   4921 N N   . GLU C 1 69  ? -12.83417 -45.67613 27.58280  1.000 51.20909  ? 29  GLU C N   1 
ATOM   4922 C CA  . GLU C 1 69  ? -12.53847 -47.02050 27.09291  1.000 61.73377  ? 29  GLU C CA  1 
ATOM   4923 C C   . GLU C 1 69  ? -11.76305 -46.98273 25.78270  1.000 61.94530  ? 29  GLU C C   1 
ATOM   4924 O O   . GLU C 1 69  ? -10.79401 -47.73063 25.60361  1.000 69.57352  ? 29  GLU C O   1 
ATOM   4925 C CB  . GLU C 1 69  ? -13.82942 -47.81959 26.91617  1.000 58.53541  ? 29  GLU C CB  1 
ATOM   4926 C CG  . GLU C 1 69  ? -13.58958 -49.26285 26.48324  1.000 68.93970  ? 29  GLU C CG  1 
ATOM   4927 C CD  . GLU C 1 69  ? -14.86197 -49.98466 26.07855  1.000 83.79397  ? 29  GLU C CD  1 
ATOM   4928 O OE1 . GLU C 1 69  ? -15.96328 -49.49533 26.40727  1.000 77.11185  ? 29  GLU C OE1 1 
ATOM   4929 O OE2 . GLU C 1 69  ? -14.75913 -51.04380 25.42564  1.000 73.84083  ? 29  GLU C OE2 1 
ATOM   4930 N N   . GLU C 1 70  ? -12.17424 -46.11980 24.85269  1.000 57.16882  ? 30  GLU C N   1 
ATOM   4931 C CA  . GLU C 1 70  ? -11.50385 -46.06129 23.56142  1.000 51.20811  ? 30  GLU C CA  1 
ATOM   4932 C C   . GLU C 1 70  ? -10.13231 -45.41639 23.65190  1.000 48.94843  ? 30  GLU C C   1 
ATOM   4933 O O   . GLU C 1 70  ? -9.28482  -45.67821 22.79161  1.000 59.04925  ? 30  GLU C O   1 
ATOM   4934 C CB  . GLU C 1 70  ? -12.36605 -45.30959 22.55049  1.000 43.91781  ? 30  GLU C CB  1 
ATOM   4935 C CG  . GLU C 1 70  ? -13.61664 -46.05980 22.14728  1.000 59.42042  ? 30  GLU C CG  1 
ATOM   4936 C CD  . GLU C 1 70  ? -13.31205 -47.42141 21.55266  1.000 59.65239  ? 30  GLU C CD  1 
ATOM   4937 O OE1 . GLU C 1 70  ? -12.32862 -47.53229 20.78989  1.000 61.70930  ? 30  GLU C OE1 1 
ATOM   4938 O OE2 . GLU C 1 70  ? -14.05612 -48.38146 21.84571  1.000 65.79416  ? 30  GLU C OE2 1 
ATOM   4939 N N   . ALA C 1 71  ? -9.90168  -44.57874 24.65460  1.000 53.14881  ? 31  ALA C N   1 
ATOM   4940 C CA  . ALA C 1 71  ? -8.59659  -43.96548 24.83713  1.000 50.00113  ? 31  ALA C CA  1 
ATOM   4941 C C   . ALA C 1 71  ? -7.55308  -45.04884 25.08041  1.000 55.83613  ? 31  ALA C C   1 
ATOM   4942 O O   . ALA C 1 71  ? -7.64362  -45.77089 26.08583  1.000 59.33376  ? 31  ALA C O   1 
ATOM   4943 C CB  . ALA C 1 71  ? -8.61958  -42.98304 26.00471  1.000 53.88783  ? 31  ALA C CB  1 
ATOM   4944 N N   . PRO C 1 72  ? -6.55796  -45.20174 24.20244  1.000 50.69839  ? 32  PRO C N   1 
ATOM   4945 C CA  . PRO C 1 72  ? -5.55495  -46.25696 24.40551  1.000 56.21442  ? 32  PRO C CA  1 
ATOM   4946 C C   . PRO C 1 72  ? -4.57871  -45.95603 25.52722  1.000 61.82658  ? 32  PRO C C   1 
ATOM   4947 O O   . PRO C 1 72  ? -3.86466  -46.86884 25.96285  1.000 63.02245  ? 32  PRO C O   1 
ATOM   4948 C CB  . PRO C 1 72  ? -4.84265  -46.32215 23.05128  1.000 56.94553  ? 32  PRO C CB  1 
ATOM   4949 C CG  . PRO C 1 72  ? -4.96294  -44.92899 22.52137  1.000 59.01323  ? 32  PRO C CG  1 
ATOM   4950 C CD  . PRO C 1 72  ? -6.32211  -44.44796 22.95836  1.000 52.45161  ? 32  PRO C CD  1 
ATOM   4951 N N   . ASP C 1 73  ? -4.52109  -44.71337 26.00107  1.000 56.91394  ? 33  ASP C N   1 
ATOM   4952 C CA  . ASP C 1 73  ? -3.62395  -44.31702 27.07535  1.000 58.85586  ? 33  ASP C CA  1 
ATOM   4953 C C   . ASP C 1 73  ? -4.34023  -44.17388 28.40884  1.000 59.33616  ? 33  ASP C C   1 
ATOM   4954 O O   . ASP C 1 73  ? -3.76747  -43.61776 29.35143  1.000 49.57327  ? 33  ASP C O   1 
ATOM   4955 C CB  . ASP C 1 73  ? -2.92887  -43.00223 26.72077  1.000 55.96682  ? 33  ASP C CB  1 
ATOM   4956 C CG  . ASP C 1 73  ? -3.90564  -41.92660 26.28935  1.000 60.10874  ? 33  ASP C CG  1 
ATOM   4957 O OD1 . ASP C 1 73  ? -5.02871  -42.27365 25.86883  1.000 58.36063  ? 33  ASP C OD1 1 
ATOM   4958 O OD2 . ASP C 1 73  ? -3.55187  -40.73174 26.37351  1.000 58.88559  ? 33  ASP C OD2 1 
ATOM   4959 N N   . MET C 1 74  ? -5.58055  -44.64717 28.50675  1.000 48.12956  ? 34  MET C N   1 
ATOM   4960 C CA  . MET C 1 74  ? -6.37541  -44.47738 29.71261  1.000 54.71874  ? 34  MET C CA  1 
ATOM   4961 C C   . MET C 1 74  ? -7.10248  -45.77055 30.04603  1.000 51.63963  ? 34  MET C C   1 
ATOM   4962 O O   . MET C 1 74  ? -7.52014  -46.51121 29.15015  1.000 56.99948  ? 34  MET C O   1 
ATOM   4963 C CB  . MET C 1 74  ? -7.38661  -43.33471 29.54544  1.000 57.33929  ? 34  MET C CB  1 
ATOM   4964 C CG  . MET C 1 74  ? -6.73864  -41.96658 29.39423  1.000 60.17357  ? 34  MET C CG  1 
ATOM   4965 S SD  . MET C 1 74  ? -7.90620  -40.69229 28.90063  1.000 63.61319  ? 34  MET C SD  1 
ATOM   4966 C CE  . MET C 1 74  ? -6.85482  -39.66584 27.87423  1.000 56.75890  ? 34  MET C CE  1 
ATOM   4967 N N   . GLU C 1 75  ? -7.24241  -46.03796 31.34090  1.000 54.44821  ? 35  GLU C N   1 
ATOM   4968 C CA  . GLU C 1 75  ? -8.08002  -47.12033 31.83000  1.000 67.54086  ? 35  GLU C CA  1 
ATOM   4969 C C   . GLU C 1 75  ? -9.00248  -46.56549 32.90526  1.000 65.29592  ? 35  GLU C C   1 
ATOM   4970 O O   . GLU C 1 75  ? -8.63977  -45.64340 33.64127  1.000 58.86676  ? 35  GLU C O   1 
ATOM   4971 C CB  . GLU C 1 75  ? -7.24573  -48.29417 32.37419  1.000 53.41805  ? 35  GLU C CB  1 
ATOM   4972 C CG  . GLU C 1 75  ? -6.70015  -48.10806 33.77974  1.000 63.67568  ? 35  GLU C CG  1 
ATOM   4973 C CD  . GLU C 1 75  ? -6.02083  -49.35774 34.30759  1.000 72.97343  ? 35  GLU C CD  1 
ATOM   4974 O OE1 . GLU C 1 75  ? -6.46905  -50.47082 33.96217  1.000 81.23540  ? 35  GLU C OE1 1 
ATOM   4975 O OE2 . GLU C 1 75  ? -5.03804  -49.22923 35.06715  1.000 76.65130  ? 35  GLU C OE2 1 
ATOM   4976 N N   . LEU C 1 76  ? -10.20806 -47.12132 32.97797  1.000 63.33868  ? 36  LEU C N   1 
ATOM   4977 C CA  . LEU C 1 76  ? -11.22651 -46.60892 33.88614  1.000 59.02865  ? 36  LEU C CA  1 
ATOM   4978 C C   . LEU C 1 76  ? -10.93518 -47.05930 35.31166  1.000 65.44911  ? 36  LEU C C   1 
ATOM   4979 O O   . LEU C 1 76  ? -10.87512 -48.26169 35.59074  1.000 64.78709  ? 36  LEU C O   1 
ATOM   4980 C CB  . LEU C 1 76  ? -12.61366 -47.07685 33.45686  1.000 55.71257  ? 36  LEU C CB  1 
ATOM   4981 C CG  . LEU C 1 76  ? -13.75208 -46.59946 34.36084  1.000 63.53488  ? 36  LEU C CG  1 
ATOM   4982 C CD1 . LEU C 1 76  ? -13.86910 -45.07730 34.32633  1.000 57.99477  ? 36  LEU C CD1 1 
ATOM   4983 C CD2 . LEU C 1 76  ? -15.06342 -47.26002 33.96962  1.000 66.76511  ? 36  LEU C CD2 1 
ATOM   4984 N N   . ALA C 1 77  ? -10.75435 -46.09352 36.21320  1.000 61.33373  ? 37  ALA C N   1 
ATOM   4985 C CA  . ALA C 1 77  ? -10.59842 -46.42015 37.62615  1.000 68.60398  ? 37  ALA C CA  1 
ATOM   4986 C C   . ALA C 1 77  ? -11.93503 -46.77714 38.26941  1.000 75.89367  ? 37  ALA C C   1 
ATOM   4987 O O   . ALA C 1 77  ? -11.99762 -47.66873 39.12287  1.000 70.58942  ? 37  ALA C O   1 
ATOM   4988 C CB  . ALA C 1 77  ? -9.93870  -45.25614 38.36813  1.000 65.07652  ? 37  ALA C CB  1 
ATOM   4989 N N   . GLY C 1 78  ? -13.00279 -46.11208 37.86773  1.000 68.81168  ? 38  GLY C N   1 
ATOM   4990 C CA  . GLY C 1 78  ? -14.30686 -46.32903 38.46235  1.000 69.19101  ? 38  GLY C CA  1 
ATOM   4991 C C   . GLY C 1 78  ? -15.16785 -45.09375 38.29902  1.000 65.54310  ? 38  GLY C C   1 
ATOM   4992 O O   . GLY C 1 78  ? -14.75086 -44.08562 37.73595  1.000 65.37429  ? 38  GLY C O   1 
ATOM   4993 N N   . VAL C 1 79  ? -16.39255 -45.19773 38.81089  1.000 70.31208  ? 39  VAL C N   1 
ATOM   4994 C CA  . VAL C 1 79  ? -17.38679 -44.13323 38.72236  1.000 60.21917  ? 39  VAL C CA  1 
ATOM   4995 C C   . VAL C 1 79  ? -17.81686 -43.74372 40.12895  1.000 63.32297  ? 39  VAL C C   1 
ATOM   4996 O O   . VAL C 1 79  ? -18.12334 -44.61356 40.95200  1.000 69.06870  ? 39  VAL C O   1 
ATOM   4997 C CB  . VAL C 1 79  ? -18.60481 -44.56215 37.88441  1.000 60.98012  ? 39  VAL C CB  1 
ATOM   4998 C CG1 . VAL C 1 79  ? -19.62270 -43.42759 37.79844  1.000 50.67215  ? 39  VAL C CG1 1 
ATOM   4999 C CG2 . VAL C 1 79  ? -18.16196 -45.00582 36.49884  1.000 56.59903  ? 39  VAL C CG2 1 
ATOM   5000 N N   . VAL C 1 80  ? -17.84036 -42.44108 40.40133  1.000 56.67185  ? 40  VAL C N   1 
ATOM   5001 C CA  . VAL C 1 80  ? -18.26586 -41.90231 41.68862  1.000 65.42292  ? 40  VAL C CA  1 
ATOM   5002 C C   . VAL C 1 80  ? -19.64921 -41.28956 41.52511  1.000 70.59656  ? 40  VAL C C   1 
ATOM   5003 O O   . VAL C 1 80  ? -19.85771 -40.43273 40.65755  1.000 74.52309  ? 40  VAL C O   1 
ATOM   5004 C CB  . VAL C 1 80  ? -17.26626 -40.86428 42.22738  1.000 67.32182  ? 40  VAL C CB  1 
ATOM   5005 C CG1 . VAL C 1 80  ? -17.78809 -40.24276 43.51552  1.000 61.84045  ? 40  VAL C CG1 1 
ATOM   5006 C CG2 . VAL C 1 80  ? -15.90671 -41.50775 42.45307  1.000 64.72509  ? 40  VAL C CG2 1 
ATOM   5007 N N   . ARG C 1 81  ? -20.59161 -41.72899 42.35595  1.000 75.54376  ? 41  ARG C N   1 
ATOM   5008 C CA  . ARG C 1 81  ? -21.95593 -41.22451 42.33741  1.000 72.38250  ? 41  ARG C CA  1 
ATOM   5009 C C   . ARG C 1 81  ? -22.36082 -40.79634 43.74148  1.000 73.59873  ? 41  ARG C C   1 
ATOM   5010 O O   . ARG C 1 81  ? -21.71103 -41.13432 44.73442  1.000 78.42062  ? 41  ARG C O   1 
ATOM   5011 C CB  . ARG C 1 81  ? -22.94044 -42.27718 41.80002  1.000 74.12950  ? 41  ARG C CB  1 
ATOM   5012 C CG  . ARG C 1 81  ? -22.47559 -42.99695 40.53946  1.000 76.30642  ? 41  ARG C CG  1 
ATOM   5013 C CD  . ARG C 1 81  ? -23.59194 -43.83838 39.93132  1.000 74.95704  ? 41  ARG C CD  1 
ATOM   5014 N NE  . ARG C 1 81  ? -24.72679 -43.03339 39.49761  1.000 70.92978  ? 41  ARG C NE  1 
ATOM   5015 C CZ  . ARG C 1 81  ? -25.78157 -43.51104 38.85092  1.000 75.55503  ? 41  ARG C CZ  1 
ATOM   5016 N NH1 . ARG C 1 81  ? -25.88690 -44.79573 38.55201  1.000 70.80759  ? 41  ARG C NH1 1 
ATOM   5017 N NH2 . ARG C 1 81  ? -26.75623 -42.67864 38.49628  1.000 86.25937  ? 41  ARG C NH2 1 
ATOM   5018 N N   . ARG C 1 82  ? -23.44711 -40.03118 43.81139  1.000 79.84933  ? 42  ARG C N   1 
ATOM   5019 C CA  . ARG C 1 82  ? -24.06211 -39.72082 45.09312  1.000 87.94620  ? 42  ARG C CA  1 
ATOM   5020 C C   . ARG C 1 82  ? -24.60056 -40.99518 45.73186  1.000 86.72070  ? 42  ARG C C   1 
ATOM   5021 O O   . ARG C 1 82  ? -24.92934 -41.96805 45.04720  1.000 87.59076  ? 42  ARG C O   1 
ATOM   5022 C CB  . ARG C 1 82  ? -25.18865 -38.70396 44.91651  1.000 73.52030  ? 42  ARG C CB  1 
ATOM   5023 C CG  . ARG C 1 82  ? -24.73031 -37.34208 44.42781  1.000 68.97235  ? 42  ARG C CG  1 
ATOM   5024 C CD  . ARG C 1 82  ? -25.91772 -36.54767 43.91560  1.000 76.09298  ? 42  ARG C CD  1 
ATOM   5025 N NE  . ARG C 1 82  ? -26.53967 -37.21075 42.77640  1.000 78.20184  ? 42  ARG C NE  1 
ATOM   5026 C CZ  . ARG C 1 82  ? -27.64359 -36.79428 42.17211  1.000 80.66730  ? 42  ARG C CZ  1 
ATOM   5027 N NH1 . ARG C 1 82  ? -28.29620 -35.72053 42.58671  1.000 80.69674  ? 42  ARG C NH1 1 
ATOM   5028 N NH2 . ARG C 1 82  ? -28.10858 -37.47754 41.12993  1.000 67.86213  ? 42  ARG C NH2 1 
ATOM   5029 N N   . GLN C 1 83  ? -24.67668 -40.98871 47.06448  1.000 92.69648  ? 43  GLN C N   1 
ATOM   5030 C CA  . GLN C 1 83  ? -25.18976 -42.15470 47.77692  1.000 96.11856  ? 43  GLN C CA  1 
ATOM   5031 C C   . GLN C 1 83  ? -26.63022 -42.45594 47.38316  1.000 83.45110  ? 43  GLN C C   1 
ATOM   5032 O O   . GLN C 1 83  ? -27.02833 -43.62452 47.30763  1.000 85.70018  ? 43  GLN C O   1 
ATOM   5033 C CB  . GLN C 1 83  ? -25.07595 -41.94162 49.28596  1.000 93.01715  ? 43  GLN C CB  1 
ATOM   5034 C CG  . GLN C 1 83  ? -23.79160 -42.49577 49.89125  1.000 90.63661  ? 43  GLN C CG  1 
ATOM   5035 C CD  . GLN C 1 83  ? -23.69178 -44.00853 49.79540  1.000 93.19542  ? 43  GLN C CD  1 
ATOM   5036 O OE1 . GLN C 1 83  ? -24.67991 -44.69674 49.53844  1.000 89.82063  ? 43  GLN C OE1 1 
ATOM   5037 N NE2 . GLN C 1 83  ? -22.48842 -44.53280 49.99646  1.000 90.87551  ? 43  GLN C NE2 1 
ATOM   5038 N N   . SER C 1 84  ? -27.43059 -41.41398 47.14322  1.000 78.85869  ? 44  SER C N   1 
ATOM   5039 C CA  . SER C 1 84  ? -28.79975 -41.62552 46.68559  1.000 80.30624  ? 44  SER C CA  1 
ATOM   5040 C C   . SER C 1 84  ? -28.82961 -42.42157 45.38626  1.000 87.51974  ? 44  SER C C   1 
ATOM   5041 O O   . SER C 1 84  ? -29.66528 -43.31708 45.21682  1.000 87.68835  ? 44  SER C O   1 
ATOM   5042 C CB  . SER C 1 84  ? -29.50903 -40.28263 46.51241  1.000 72.23810  ? 44  SER C CB  1 
ATOM   5043 O OG  . SER C 1 84  ? -28.98703 -39.56727 45.40722  1.000 84.20293  ? 44  SER C OG  1 
ATOM   5044 N N   . SER C 1 85  ? -27.92240 -42.11115 44.45866  1.000 88.30810  ? 45  SER C N   1 
ATOM   5045 C CA  . SER C 1 85  ? -27.87196 -42.80534 43.17897  1.000 87.57912  ? 45  SER C CA  1 
ATOM   5046 C C   . SER C 1 85  ? -27.23419 -44.18578 43.27921  1.000 90.12180  ? 45  SER C C   1 
ATOM   5047 O O   . SER C 1 85  ? -27.41740 -45.00605 42.37298  1.000 88.55628  ? 45  SER C O   1 
ATOM   5048 C CB  . SER C 1 85  ? -27.10913 -41.96130 42.15632  1.000 83.24732  ? 45  SER C CB  1 
ATOM   5049 O OG  . SER C 1 85  ? -27.73878 -40.70581 41.96001  1.000 87.21356  ? 45  SER C OG  1 
ATOM   5050 N N   . LEU C 1 86  ? -26.49110 -44.46382 44.35349  1.000 90.37549  ? 46  LEU C N   1 
ATOM   5051 C CA  . LEU C 1 86  ? -25.83021 -45.75691 44.47798  1.000 88.80281  ? 46  LEU C CA  1 
ATOM   5052 C C   . LEU C 1 86  ? -26.81504 -46.87872 44.76739  1.000 97.35106  ? 46  LEU C C   1 
ATOM   5053 O O   . LEU C 1 86  ? -26.51906 -48.04344 44.48390  1.000 93.77993  ? 46  LEU C O   1 
ATOM   5054 C CB  . LEU C 1 86  ? -24.78897 -45.70713 45.59408  1.000 85.39626  ? 46  LEU C CB  1 
ATOM   5055 C CG  . LEU C 1 86  ? -23.41372 -45.11316 45.28786  1.000 83.85832  ? 46  LEU C CG  1 
ATOM   5056 C CD1 . LEU C 1 86  ? -22.53402 -45.15289 46.53000  1.000 90.67404  ? 46  LEU C CD1 1 
ATOM   5057 C CD2 . LEU C 1 86  ? -22.76089 -45.85922 44.14360  1.000 79.33279  ? 46  LEU C CD2 1 
ATOM   5058 N N   . GLU C 1 87  ? -27.97637 -46.55976 45.32576  1.000 101.15934 ? 47  GLU C N   1 
ATOM   5059 C CA  . GLU C 1 87  ? -28.97108 -47.56387 45.66998  1.000 102.96535 ? 47  GLU C CA  1 
ATOM   5060 C C   . GLU C 1 87  ? -30.09157 -47.66404 44.64635  1.000 93.49393  ? 47  GLU C C   1 
ATOM   5061 O O   . GLU C 1 87  ? -30.97717 -48.51579 44.79223  1.000 104.12528 ? 47  GLU C O   1 
ATOM   5062 C CB  . GLU C 1 87  ? -29.48964 -47.31825 47.08721  1.000 109.32059 ? 47  GLU C CB  1 
ATOM   5063 C CG  . GLU C 1 87  ? -28.32694 -47.31064 48.08621  1.000 122.20167 ? 47  GLU C CG  1 
ATOM   5064 C CD  . GLU C 1 87  ? -28.68631 -46.73901 49.44044  1.000 133.72177 ? 47  GLU C CD  1 
ATOM   5065 O OE1 . GLU C 1 87  ? -29.72417 -46.05510 49.54485  1.000 133.20028 ? 47  GLU C OE1 1 
ATOM   5066 O OE2 . GLU C 1 87  ? -27.93044 -46.99058 50.40136  1.000 135.43936 ? 47  GLU C OE2 1 
ATOM   5067 N N   . LYS C 1 88  ? -30.07871 -46.80929 43.62549  1.000 90.37390  ? 48  LYS C N   1 
ATOM   5068 C CA  . LYS C 1 88  ? -30.91544 -47.05002 42.47453  1.000 88.86713  ? 48  LYS C CA  1 
ATOM   5069 C C   . LYS C 1 88  ? -30.31649 -48.23364 41.71415  1.000 88.59681  ? 48  LYS C C   1 
ATOM   5070 O O   . LYS C 1 88  ? -29.13435 -48.53934 41.88223  1.000 83.73870  ? 48  LYS C O   1 
ATOM   5071 C CB  . LYS C 1 88  ? -30.98394 -45.80282 41.59800  1.000 88.76281  ? 48  LYS C CB  1 
ATOM   5072 C CG  . LYS C 1 88  ? -31.44557 -44.55083 42.34737  1.000 100.76416 ? 48  LYS C CG  1 
ATOM   5073 C CD  . LYS C 1 88  ? -31.54930 -43.33862 41.41755  1.000 93.24410  ? 48  LYS C CD  1 
ATOM   5074 C CE  . LYS C 1 88  ? -30.41103 -43.30000 40.40762  1.000 99.46479  ? 48  LYS C CE  1 
ATOM   5075 N NZ  . LYS C 1 88  ? -30.57068 -42.10759 39.51611  1.000 86.39145  ? 48  LYS C NZ  1 
ATOM   5076 N N   . PRO C 1 89  ? -31.10198 -48.92224 40.87889  1.000 92.24763  ? 49  PRO C N   1 
ATOM   5077 C CA  . PRO C 1 89  ? -30.57494 -50.12544 40.21372  1.000 85.38872  ? 49  PRO C CA  1 
ATOM   5078 C C   . PRO C 1 89  ? -29.33223 -49.83262 39.38524  1.000 79.68134  ? 49  PRO C C   1 
ATOM   5079 O O   . PRO C 1 89  ? -29.21346 -48.78010 38.75621  1.000 84.62547  ? 49  PRO C O   1 
ATOM   5080 C CB  . PRO C 1 89  ? -31.74325 -50.59317 39.33481  1.000 78.29111  ? 49  PRO C CB  1 
ATOM   5081 C CG  . PRO C 1 89  ? -32.65045 -49.41202 39.22544  1.000 91.49995  ? 49  PRO C CG  1 
ATOM   5082 C CD  . PRO C 1 89  ? -32.50610 -48.66931 40.51287  1.000 91.09793  ? 49  PRO C CD  1 
ATOM   5083 N N   . LEU C 1 90  ? -28.40445 -50.78192 39.39515  1.000 73.34183  ? 50  LEU C N   1 
ATOM   5084 C CA  . LEU C 1 90  ? -27.12225 -50.60400 38.72161  1.000 71.75885  ? 50  LEU C CA  1 
ATOM   5085 C C   . LEU C 1 90  ? -27.31368 -50.62642 37.21128  1.000 70.20167  ? 50  LEU C C   1 
ATOM   5086 O O   . LEU C 1 90  ? -27.86394 -51.60063 36.68121  1.000 80.63930  ? 50  LEU C O   1 
ATOM   5087 C CB  . LEU C 1 90  ? -26.14144 -51.69032 39.15079  1.000 75.92710  ? 50  LEU C CB  1 
ATOM   5088 C CG  . LEU C 1 90  ? -24.78120 -51.69089 38.44876  1.000 85.50241  ? 50  LEU C CG  1 
ATOM   5089 C CD1 . LEU C 1 90  ? -23.93381 -50.51451 38.91413  1.000 79.00123  ? 50  LEU C CD1 1 
ATOM   5090 C CD2 . LEU C 1 90  ? -24.05577 -53.00638 38.68235  1.000 78.80112  ? 50  LEU C CD2 1 
ATOM   5091 N N   . PRO C 1 91  ? -26.89726 -49.58742 36.48823  1.000 78.33911  ? 51  PRO C N   1 
ATOM   5092 C CA  . PRO C 1 91  ? -27.02865 -49.60249 35.02726  1.000 70.37296  ? 51  PRO C CA  1 
ATOM   5093 C C   . PRO C 1 91  ? -26.26951 -50.76752 34.40939  1.000 76.95198  ? 51  PRO C C   1 
ATOM   5094 O O   . PRO C 1 91  ? -25.22566 -51.19552 34.90742  1.000 73.28986  ? 51  PRO C O   1 
ATOM   5095 C CB  . PRO C 1 91  ? -26.43029 -48.25553 34.60481  1.000 68.32143  ? 51  PRO C CB  1 
ATOM   5096 C CG  . PRO C 1 91  ? -26.57844 -47.38619 35.81784  1.000 80.20229  ? 51  PRO C CG  1 
ATOM   5097 C CD  . PRO C 1 91  ? -26.36087 -48.30826 36.98178  1.000 83.90885  ? 51  PRO C CD  1 
ATOM   5098 N N   . ARG C 1 92  ? -26.81937 -51.28655 33.30885  1.000 75.59330  ? 52  ARG C N   1 
ATOM   5099 C CA  . ARG C 1 92  ? -26.29390 -52.51503 32.72232  1.000 74.86817  ? 52  ARG C CA  1 
ATOM   5100 C C   . ARG C 1 92  ? -24.88348 -52.32716 32.17175  1.000 80.20885  ? 52  ARG C C   1 
ATOM   5101 O O   . ARG C 1 92  ? -24.09854 -53.28233 32.14659  1.000 80.58926  ? 52  ARG C O   1 
ATOM   5102 C CB  . ARG C 1 92  ? -27.24277 -53.01769 31.63142  1.000 70.08777  ? 52  ARG C CB  1 
ATOM   5103 C CG  . ARG C 1 92  ? -26.81795 -54.33046 30.99975  1.000 84.81017  ? 52  ARG C CG  1 
ATOM   5104 C CD  . ARG C 1 92  ? -27.81182 -54.83610 29.96514  1.000 93.46208  ? 52  ARG C CD  1 
ATOM   5105 N NE  . ARG C 1 92  ? -28.95041 -55.51360 30.57237  1.000 93.24451  ? 52  ARG C NE  1 
ATOM   5106 C CZ  . ARG C 1 92  ? -30.11950 -54.94139 30.82156  1.000 98.87682  ? 52  ARG C CZ  1 
ATOM   5107 N NH1 . ARG C 1 92  ? -30.34521 -53.67297 30.52280  1.000 98.70626  ? 52  ARG C NH1 1 
ATOM   5108 N NH2 . ARG C 1 92  ? -31.08729 -55.66094 31.38298  1.000 103.48547 ? 52  ARG C NH2 1 
ATOM   5109 N N   . GLU C 1 93  ? -24.53469 -51.11309 31.74369  1.000 79.18789  ? 53  GLU C N   1 
ATOM   5110 C CA  . GLU C 1 93  ? -23.20068 -50.86094 31.21296  1.000 78.90590  ? 53  GLU C CA  1 
ATOM   5111 C C   . GLU C 1 93  ? -22.15338 -50.69634 32.30611  1.000 71.28262  ? 53  GLU C C   1 
ATOM   5112 O O   . GLU C 1 93  ? -20.95607 -50.68600 31.99890  1.000 72.52789  ? 53  GLU C O   1 
ATOM   5113 C CB  . GLU C 1 93  ? -23.20853 -49.61313 30.32502  1.000 76.41795  ? 53  GLU C CB  1 
ATOM   5114 C CG  . GLU C 1 93  ? -23.49166 -48.32135 31.07280  1.000 72.28300  ? 53  GLU C CG  1 
ATOM   5115 C CD  . GLU C 1 93  ? -24.97193 -48.05310 31.26247  1.000 76.37243  ? 53  GLU C CD  1 
ATOM   5116 O OE1 . GLU C 1 93  ? -25.78477 -48.97003 31.01837  1.000 77.93865  ? 53  GLU C OE1 1 
ATOM   5117 O OE2 . GLU C 1 93  ? -25.31942 -46.92256 31.66351  1.000 79.68662  ? 53  GLU C OE2 1 
ATOM   5118 N N   . LEU C 1 94  ? -22.57094 -50.56514 33.56355  1.000 69.79721  ? 54  LEU C N   1 
ATOM   5119 C CA  . LEU C 1 94  ? -21.65521 -50.43493 34.68633  1.000 64.25393  ? 54  LEU C CA  1 
ATOM   5120 C C   . LEU C 1 94  ? -21.37515 -51.76707 35.36974  1.000 74.88688  ? 54  LEU C C   1 
ATOM   5121 O O   . LEU C 1 94  ? -20.77447 -51.78314 36.44867  1.000 79.81616  ? 54  LEU C O   1 
ATOM   5122 C CB  . LEU C 1 94  ? -22.20576 -49.43309 35.70181  1.000 68.35576  ? 54  LEU C CB  1 
ATOM   5123 C CG  . LEU C 1 94  ? -22.28227 -47.98197 35.22760  1.000 70.63867  ? 54  LEU C CG  1 
ATOM   5124 C CD1 . LEU C 1 94  ? -22.72413 -47.07497 36.36124  1.000 69.37085  ? 54  LEU C CD1 1 
ATOM   5125 C CD2 . LEU C 1 94  ? -20.94688 -47.52787 34.66384  1.000 66.14706  ? 54  LEU C CD2 1 
ATOM   5126 N N   . HIS C 1 95  ? -21.80637 -52.87902 34.77590  1.000 78.17454  ? 55  HIS C N   1 
ATOM   5127 C CA  . HIS C 1 95  ? -21.48260 -54.19237 35.31749  1.000 73.53274  ? 55  HIS C CA  1 
ATOM   5128 C C   . HIS C 1 95  ? -19.97971 -54.42753 35.26363  1.000 83.74212  ? 55  HIS C C   1 
ATOM   5129 O O   . HIS C 1 95  ? -19.34922 -54.26468 34.21461  1.000 81.48465  ? 55  HIS C O   1 
ATOM   5130 C CB  . HIS C 1 95  ? -22.21898 -55.28457 34.54230  1.000 75.54228  ? 55  HIS C CB  1 
ATOM   5131 C CG  . HIS C 1 95  ? -23.64838 -55.45733 34.95192  1.000 101.15863 ? 55  HIS C CG  1 
ATOM   5132 N ND1 . HIS C 1 95  ? -24.68836 -55.45830 34.04728  1.000 101.96963 ? 55  HIS C ND1 1 
ATOM   5133 C CD2 . HIS C 1 95  ? -24.20951 -55.64674 36.16970  1.000 105.56017 ? 55  HIS C CD2 1 
ATOM   5134 C CE1 . HIS C 1 95  ? -25.82898 -55.63373 34.69054  1.000 89.79783  ? 55  HIS C CE1 1 
ATOM   5135 N NE2 . HIS C 1 95  ? -25.56620 -55.75134 35.97962  1.000 96.59787  ? 55  HIS C NE2 1 
ATOM   5136 N N   . GLY C 1 96  ? -19.40683 -54.81585 36.39955  1.000 82.54259  ? 56  GLY C N   1 
ATOM   5137 C CA  . GLY C 1 96  ? -17.97208 -54.97383 36.49469  1.000 65.22765  ? 56  GLY C CA  1 
ATOM   5138 C C   . GLY C 1 96  ? -17.20702 -53.68507 36.67942  1.000 82.60844  ? 56  GLY C C   1 
ATOM   5139 O O   . GLY C 1 96  ? -15.97231 -53.69953 36.61297  1.000 77.63609  ? 56  GLY C O   1 
ATOM   5140 N N   . VAL C 1 97  ? -17.89750 -52.57219 36.91017  1.000 68.00862  ? 57  VAL C N   1 
ATOM   5141 C CA  . VAL C 1 97  ? -17.27433 -51.26900 37.09709  1.000 66.16786  ? 57  VAL C CA  1 
ATOM   5142 C C   . VAL C 1 97  ? -17.46042 -50.86487 38.55123  1.000 75.64299  ? 57  VAL C C   1 
ATOM   5143 O O   . VAL C 1 97  ? -18.57226 -50.94736 39.08734  1.000 79.28603  ? 57  VAL C O   1 
ATOM   5144 C CB  . VAL C 1 97  ? -17.87565 -50.21755 36.14824  1.000 62.47603  ? 57  VAL C CB  1 
ATOM   5145 C CG1 . VAL C 1 97  ? -17.33993 -48.83199 36.47417  1.000 63.15924  ? 57  VAL C CG1 1 
ATOM   5146 C CG2 . VAL C 1 97  ? -17.58643 -50.58145 34.70014  1.000 54.07422  ? 57  VAL C CG2 1 
ATOM   5147 N N   . SER C 1 98  ? -16.37308 -50.44167 39.19049  1.000 76.25408  ? 58  SER C N   1 
ATOM   5148 C CA  . SER C 1 98  ? -16.43068 -49.97916 40.57309  1.000 70.57813  ? 58  SER C CA  1 
ATOM   5149 C C   . SER C 1 98  ? -17.22474 -48.68108 40.64450  1.000 76.57591  ? 58  SER C C   1 
ATOM   5150 O O   . SER C 1 98  ? -16.77811 -47.64121 40.14910  1.000 75.52663  ? 58  SER C O   1 
ATOM   5151 C CB  . SER C 1 98  ? -15.02152 -49.78586 41.12210  1.000 65.55538  ? 58  SER C CB  1 
ATOM   5152 O OG  . SER C 1 98  ? -14.28012 -50.99040 41.04783  1.000 77.50773  ? 58  SER C OG  1 
ATOM   5153 N N   . VAL C 1 99  ? -18.40184 -48.73796 41.26018  1.000 70.54921  ? 59  VAL C N   1 
ATOM   5154 C CA  . VAL C 1 99  ? -19.26388 -47.57627 41.43968  1.000 74.30648  ? 59  VAL C CA  1 
ATOM   5155 C C   . VAL C 1 99  ? -19.35121 -47.31298 42.93660  1.000 71.42642  ? 59  VAL C C   1 
ATOM   5156 O O   . VAL C 1 99  ? -19.96933 -48.08986 43.67669  1.000 82.53139  ? 59  VAL C O   1 
ATOM   5157 C CB  . VAL C 1 99  ? -20.65417 -47.79098 40.82909  1.000 64.06574  ? 59  VAL C CB  1 
ATOM   5158 C CG1 . VAL C 1 99  ? -21.43828 -46.49970 40.85237  1.000 52.49764  ? 59  VAL C CG1 1 
ATOM   5159 C CG2 . VAL C 1 99  ? -20.53197 -48.31906 39.40665  1.000 60.35235  ? 59  VAL C CG2 1 
ATOM   5160 N N   . VAL C 1 100 ? -18.73657 -46.21925 43.38387  1.000 70.08167  ? 60  VAL C N   1 
ATOM   5161 C CA  . VAL C 1 100 ? -18.57154 -45.91492 44.79635  1.000 76.98570  ? 60  VAL C CA  1 
ATOM   5162 C C   . VAL C 1 100 ? -19.04188 -44.48598 45.05410  1.000 77.25591  ? 60  VAL C C   1 
ATOM   5163 O O   . VAL C 1 100 ? -19.48595 -43.78221 44.14819  1.000 78.46202  ? 60  VAL C O   1 
ATOM   5164 C CB  . VAL C 1 100 ? -17.11533 -46.10725 45.26823  1.000 76.26417  ? 60  VAL C CB  1 
ATOM   5165 C CG1 . VAL C 1 100 ? -16.65964 -47.54018 45.03024  1.000 69.61493  ? 60  VAL C CG1 1 
ATOM   5166 C CG2 . VAL C 1 100 ? -16.20345 -45.13847 44.54627  1.000 75.94942  ? 60  VAL C CG2 1 
ATOM   5167 N N   . SER C 1 101 ? -18.93660 -44.06427 46.31531  1.000 84.63674  ? 61  SER C N   1 
ATOM   5168 C CA  . SER C 1 101 ? -19.38117 -42.74352 46.73983  1.000 82.40405  ? 61  SER C CA  1 
ATOM   5169 C C   . SER C 1 101 ? -18.24246 -41.74887 46.93463  1.000 84.36795  ? 61  SER C C   1 
ATOM   5170 O O   . SER C 1 101 ? -18.51164 -40.55317 47.09324  1.000 81.77960  ? 61  SER C O   1 
ATOM   5171 C CB  . SER C 1 101 ? -20.18098 -42.85155 48.04418  1.000 81.40662  ? 61  SER C CB  1 
ATOM   5172 O OG  . SER C 1 101 ? -19.34942 -43.26168 49.11679  1.000 83.21607  ? 61  SER C OG  1 
ATOM   5173 N N   . ASP C 1 102 ? -16.98949 -42.20160 46.92962  1.000 71.55784  ? 62  ASP C N   1 
ATOM   5174 C CA  . ASP C 1 102 ? -15.85355 -41.30297 47.07638  1.000 78.92543  ? 62  ASP C CA  1 
ATOM   5175 C C   . ASP C 1 102 ? -14.67712 -41.84892 46.28054  1.000 79.63883  ? 62  ASP C C   1 
ATOM   5176 O O   . ASP C 1 102 ? -14.49859 -43.06363 46.16136  1.000 75.20518  ? 62  ASP C O   1 
ATOM   5177 C CB  . ASP C 1 102 ? -15.46249 -41.11839 48.54755  1.000 77.49689  ? 62  ASP C CB  1 
ATOM   5178 C CG  . ASP C 1 102 ? -14.31759 -40.13882 48.72778  1.000 89.76112  ? 62  ASP C CG  1 
ATOM   5179 O OD1 . ASP C 1 102 ? -14.53752 -38.92193 48.55338  1.000 98.80806  ? 62  ASP C OD1 1 
ATOM   5180 O OD2 . ASP C 1 102 ? -13.19686 -40.58537 49.04297  1.000 80.18895  ? 62  ASP C OD2 1 
ATOM   5181 N N   . VAL C 1 103 ? -13.86987 -40.93109 45.74220  1.000 79.11119  ? 63  VAL C N   1 
ATOM   5182 C CA  . VAL C 1 103 ? -12.76528 -41.30606 44.86738  1.000 71.60084  ? 63  VAL C CA  1 
ATOM   5183 C C   . VAL C 1 103 ? -11.72108 -42.14742 45.59061  1.000 73.21140  ? 63  VAL C C   1 
ATOM   5184 O O   . VAL C 1 103 ? -10.96862 -42.88523 44.94530  1.000 79.25933  ? 63  VAL C O   1 
ATOM   5185 C CB  . VAL C 1 103 ? -12.13530 -40.03404 44.25595  1.000 69.26854  ? 63  VAL C CB  1 
ATOM   5186 C CG1 . VAL C 1 103 ? -11.40278 -39.23220 45.32035  1.000 71.15152  ? 63  VAL C CG1 1 
ATOM   5187 C CG2 . VAL C 1 103 ? -11.20722 -40.38299 43.09933  1.000 64.70328  ? 63  VAL C CG2 1 
ATOM   5188 N N   . SER C 1 104 ? -11.65318 -42.05903 46.92212  1.000 77.17418  ? 64  SER C N   1 
ATOM   5189 C CA  . SER C 1 104 ? -10.64795 -42.81261 47.66517  1.000 77.44184  ? 64  SER C CA  1 
ATOM   5190 C C   . SER C 1 104 ? -10.85017 -44.31845 47.55743  1.000 78.30397  ? 64  SER C C   1 
ATOM   5191 O O   . SER C 1 104 ? -9.89157  -45.07541 47.74542  1.000 85.68603  ? 64  SER C O   1 
ATOM   5192 C CB  . SER C 1 104 ? -10.65025 -42.39371 49.13566  1.000 78.02062  ? 64  SER C CB  1 
ATOM   5193 O OG  . SER C 1 104 ? -11.92100 -42.60709 49.72357  1.000 85.10915  ? 64  SER C OG  1 
ATOM   5194 N N   . ALA C 1 105 ? -12.06818 -44.76974 47.26271  1.000 75.18808  ? 65  ALA C N   1 
ATOM   5195 C CA  . ALA C 1 105 ? -12.36093 -46.19384 47.15899  1.000 78.26386  ? 65  ALA C CA  1 
ATOM   5196 C C   . ALA C 1 105 ? -12.01168 -46.78183 45.79657  1.000 77.89388  ? 65  ALA C C   1 
ATOM   5197 O O   . ALA C 1 105 ? -12.26041 -47.97170 45.57423  1.000 71.01626  ? 65  ALA C O   1 
ATOM   5198 C CB  . ALA C 1 105 ? -13.84002 -46.44798 47.46360  1.000 59.83802  ? 65  ALA C CB  1 
ATOM   5199 N N   . LEU C 1 106 ? -11.44764 -45.98928 44.88598  1.000 79.97487  ? 66  LEU C N   1 
ATOM   5200 C CA  . LEU C 1 106 ? -11.12616 -46.43666 43.53679  1.000 79.44595  ? 66  LEU C CA  1 
ATOM   5201 C C   . LEU C 1 106 ? -9.64353  -46.72979 43.34765  1.000 75.39264  ? 66  LEU C C   1 
ATOM   5202 O O   . LEU C 1 106 ? -9.20407  -46.94704 42.21369  1.000 71.30291  ? 66  LEU C O   1 
ATOM   5203 C CB  . LEU C 1 106 ? -11.58480 -45.39498 42.51345  1.000 72.67754  ? 66  LEU C CB  1 
ATOM   5204 C CG  . LEU C 1 106 ? -13.09122 -45.14879 42.42771  1.000 73.03588  ? 66  LEU C CG  1 
ATOM   5205 C CD1 . LEU C 1 106 ? -13.40068 -44.10454 41.36759  1.000 74.34902  ? 66  LEU C CD1 1 
ATOM   5206 C CD2 . LEU C 1 106 ? -13.82184 -46.44910 42.13202  1.000 70.62220  ? 66  LEU C CD2 1 
ATOM   5207 N N   . GLY C 1 107 ? -8.86731  -46.74681 44.42816  1.000 76.20564  ? 67  GLY C N   1 
ATOM   5208 C CA  . GLY C 1 107 ? -7.43819  -46.93820 44.30544  1.000 69.43530  ? 67  GLY C CA  1 
ATOM   5209 C C   . GLY C 1 107 ? -6.75838  -45.69028 43.76933  1.000 75.51909  ? 67  GLY C C   1 
ATOM   5210 O O   . GLY C 1 107 ? -7.19885  -44.55846 43.99440  1.000 72.69470  ? 67  GLY C O   1 
ATOM   5211 N N   . GLN C 1 108 ? -5.66140  -45.90397 43.04781  1.000 77.00064  ? 68  GLN C N   1 
ATOM   5212 C CA  . GLN C 1 108 ? -4.91091  -44.79344 42.47613  1.000 72.48938  ? 68  GLN C CA  1 
ATOM   5213 C C   . GLN C 1 108 ? -5.72776  -44.14200 41.36453  1.000 74.56126  ? 68  GLN C C   1 
ATOM   5214 O O   . GLN C 1 108 ? -6.15905  -44.81817 40.42438  1.000 75.31459  ? 68  GLN C O   1 
ATOM   5215 C CB  . GLN C 1 108 ? -3.56208  -45.28340 41.94976  1.000 72.05652  ? 68  GLN C CB  1 
ATOM   5216 C CG  . GLN C 1 108 ? -2.81428  -44.28744 41.06078  1.000 72.57690  ? 68  GLN C CG  1 
ATOM   5217 C CD  . GLN C 1 108 ? -2.24965  -43.08843 41.82217  1.000 77.68315  ? 68  GLN C CD  1 
ATOM   5218 O OE1 . GLN C 1 108 ? -2.68855  -42.76407 42.92635  1.000 90.96229  ? 68  GLN C OE1 1 
ATOM   5219 N NE2 . GLN C 1 108 ? -1.26474  -42.42641 41.22476  1.000 93.85381  ? 68  GLN C NE2 1 
ATOM   5220 N N   . VAL C 1 109 ? -5.94181  -42.83185 41.47153  1.000 66.32726  ? 69  VAL C N   1 
ATOM   5221 C CA  . VAL C 1 109 ? -6.69517  -42.06237 40.48494  1.000 67.79084  ? 69  VAL C CA  1 
ATOM   5222 C C   . VAL C 1 109 ? -5.83376  -40.88097 40.06360  1.000 63.62831  ? 69  VAL C C   1 
ATOM   5223 O O   . VAL C 1 109 ? -5.54262  -39.99759 40.87973  1.000 66.40307  ? 69  VAL C O   1 
ATOM   5224 C CB  . VAL C 1 109 ? -8.04788  -41.58230 41.02829  1.000 62.82471  ? 69  VAL C CB  1 
ATOM   5225 C CG1 . VAL C 1 109 ? -8.73008  -40.66127 40.02143  1.000 63.31737  ? 69  VAL C CG1 1 
ATOM   5226 C CG2 . VAL C 1 109 ? -8.93162  -42.76744 41.35702  1.000 63.77886  ? 69  VAL C CG2 1 
ATOM   5227 N N   . ASP C 1 110 ? -5.42449  -40.86214 38.79409  1.000 63.67241  ? 70  ASP C N   1 
ATOM   5228 C CA  . ASP C 1 110 ? -4.62243  -39.75283 38.28916  1.000 62.70987  ? 70  ASP C CA  1 
ATOM   5229 C C   . ASP C 1 110 ? -5.48518  -38.54106 37.95198  1.000 62.44920  ? 70  ASP C C   1 
ATOM   5230 O O   . ASP C 1 110 ? -5.17714  -37.41670 38.36283  1.000 65.72963  ? 70  ASP C O   1 
ATOM   5231 C CB  . ASP C 1 110 ? -3.82296  -40.19837 37.06343  1.000 66.34087  ? 70  ASP C CB  1 
ATOM   5232 C CG  . ASP C 1 110 ? -2.80537  -41.27434 37.39066  1.000 64.43143  ? 70  ASP C CG  1 
ATOM   5233 O OD1 . ASP C 1 110 ? -1.96161  -41.04489 38.28359  1.000 75.31722  ? 70  ASP C OD1 1 
ATOM   5234 O OD2 . ASP C 1 110 ? -2.84434  -42.34781 36.75304  1.000 69.07763  ? 70  ASP C OD2 1 
ATOM   5235 N N   . VAL C 1 111 ? -6.56901  -38.74958 37.20774  1.000 59.77928  ? 71  VAL C N   1 
ATOM   5236 C CA  . VAL C 1 111 ? -7.41183  -37.66658 36.71644  1.000 61.62295  ? 71  VAL C CA  1 
ATOM   5237 C C   . VAL C 1 111 ? -8.86164  -37.98322 37.05160  1.000 60.76178  ? 71  VAL C C   1 
ATOM   5238 O O   . VAL C 1 111 ? -9.30851  -39.12558 36.90178  1.000 61.95204  ? 71  VAL C O   1 
ATOM   5239 C CB  . VAL C 1 111 ? -7.24119  -37.46081 35.19363  1.000 59.84387  ? 71  VAL C CB  1 
ATOM   5240 C CG1 . VAL C 1 111 ? -8.12738  -36.32903 34.69488  1.000 57.73773  ? 71  VAL C CG1 1 
ATOM   5241 C CG2 . VAL C 1 111 ? -5.78239  -37.19893 34.84268  1.000 49.67097  ? 71  VAL C CG2 1 
ATOM   5242 N N   . ALA C 1 112 ? -9.59335  -36.97260 37.51131  1.000 57.48109  ? 72  ALA C N   1 
ATOM   5243 C CA  . ALA C 1 112 ? -11.03085 -37.06859 37.72819  1.000 54.93660  ? 72  ALA C CA  1 
ATOM   5244 C C   . ALA C 1 112 ? -11.73841 -36.21595 36.68464  1.000 57.12730  ? 72  ALA C C   1 
ATOM   5245 O O   . ALA C 1 112 ? -11.46061 -35.01733 36.56626  1.000 51.11608  ? 72  ALA C O   1 
ATOM   5246 C CB  . ALA C 1 112 ? -11.40788 -36.61671 39.13760  1.000 54.72477  ? 72  ALA C CB  1 
ATOM   5247 N N   . VAL C 1 113 ? -12.64973 -36.83009 35.93821  1.000 54.71565  ? 73  VAL C N   1 
ATOM   5248 C CA  . VAL C 1 113 ? -13.41088 -36.14702 34.89939  1.000 55.47526  ? 73  VAL C CA  1 
ATOM   5249 C C   . VAL C 1 113 ? -14.77027 -35.79782 35.48972  1.000 64.73536  ? 73  VAL C C   1 
ATOM   5250 O O   . VAL C 1 113 ? -15.57609 -36.68224 35.79980  1.000 57.95383  ? 73  VAL C O   1 
ATOM   5251 C CB  . VAL C 1 113 ? -13.54465 -37.00334 33.63390  1.000 57.58449  ? 73  VAL C CB  1 
ATOM   5252 C CG1 . VAL C 1 113 ? -14.49566 -36.34267 32.64963  1.000 44.28466  ? 73  VAL C CG1 1 
ATOM   5253 C CG2 . VAL C 1 113 ? -12.17879 -37.21438 32.99676  1.000 52.03946  ? 73  VAL C CG2 1 
ATOM   5254 N N   . LEU C 1 114 ? -15.02651 -34.50324 35.64248  1.000 62.16615  ? 74  LEU C N   1 
ATOM   5255 C CA  . LEU C 1 114 ? -16.17608 -34.01458 36.39927  1.000 61.14048  ? 74  LEU C CA  1 
ATOM   5256 C C   . LEU C 1 114 ? -17.36459 -33.87070 35.45802  1.000 60.90098  ? 74  LEU C C   1 
ATOM   5257 O O   . LEU C 1 114 ? -17.43359 -32.92956 34.66477  1.000 58.34270  ? 74  LEU C O   1 
ATOM   5258 C CB  . LEU C 1 114 ? -15.84403 -32.68999 37.07602  1.000 58.05534  ? 74  LEU C CB  1 
ATOM   5259 C CG  . LEU C 1 114 ? -15.13708 -32.69383 38.43362  1.000 57.81599  ? 74  LEU C CG  1 
ATOM   5260 C CD1 . LEU C 1 114 ? -13.99214 -33.69602 38.50321  1.000 52.05761  ? 74  LEU C CD1 1 
ATOM   5261 C CD2 . LEU C 1 114 ? -14.63190 -31.30333 38.72970  1.000 57.50000  ? 74  LEU C CD2 1 
ATOM   5262 N N   . CYS C 1 115 ? -18.31516 -34.79834 35.55975  1.000 56.24415  ? 75  CYS C N   1 
ATOM   5263 C CA  . CYS C 1 115 ? -19.53577 -34.74200 34.76438  1.000 63.08080  ? 75  CYS C CA  1 
ATOM   5264 C C   . CYS C 1 115 ? -20.71992 -34.38418 35.65613  1.000 67.51743  ? 75  CYS C C   1 
ATOM   5265 O O   . CYS C 1 115 ? -21.77803 -35.01921 35.58893  1.000 66.36094  ? 75  CYS C O   1 
ATOM   5266 C CB  . CYS C 1 115 ? -19.77386 -36.07429 34.04955  1.000 57.37192  ? 75  CYS C CB  1 
ATOM   5267 S SG  . CYS C 1 115 ? -18.28726 -36.77834 33.29515  1.000 68.00465  ? 75  CYS C SG  1 
ATOM   5268 N N   . THR C 1 116 ? -20.54112 -33.36909 36.48794  1.000 62.51431  ? 76  THR C N   1 
ATOM   5269 C CA  . THR C 1 116 ? -21.48043 -32.92316 37.50190  1.000 65.72017  ? 76  THR C CA  1 
ATOM   5270 C C   . THR C 1 116 ? -22.16852 -31.63221 37.06842  1.000 63.23967  ? 76  THR C C   1 
ATOM   5271 O O   . THR C 1 116 ? -21.73088 -30.96891 36.12274  1.000 56.55828  ? 76  THR C O   1 
ATOM   5272 C CB  . THR C 1 116 ? -20.74030 -32.70655 38.82844  1.000 67.36651  ? 76  THR C CB  1 
ATOM   5273 O OG1 . THR C 1 116 ? -19.58441 -31.88982 38.60329  1.000 61.10520  ? 76  THR C OG1 1 
ATOM   5274 C CG2 . THR C 1 116 ? -20.30934 -34.03886 39.42183  1.000 60.55909  ? 76  THR C CG2 1 
ATOM   5275 N N   . PRO C 1 117 ? -23.26470 -31.24882 37.73050  1.000 67.84855  ? 77  PRO C N   1 
ATOM   5276 C CA  . PRO C 1 117 ? -23.93667 -29.99737 37.36045  1.000 58.99850  ? 77  PRO C CA  1 
ATOM   5277 C C   . PRO C 1 117 ? -23.03245 -28.78962 37.55923  1.000 59.36881  ? 77  PRO C C   1 
ATOM   5278 O O   . PRO C 1 117 ? -22.11670 -28.79694 38.38497  1.000 73.54261  ? 77  PRO C O   1 
ATOM   5279 C CB  . PRO C 1 117 ? -25.14812 -29.95148 38.29877  1.000 61.97181  ? 77  PRO C CB  1 
ATOM   5280 C CG  . PRO C 1 117 ? -25.41014 -31.36858 38.63677  1.000 69.91181  ? 77  PRO C CG  1 
ATOM   5281 C CD  . PRO C 1 117 ? -24.06330 -32.02594 38.69522  1.000 69.43194  ? 77  PRO C CD  1 
ATOM   5282 N N   . THR C 1 118 ? -23.29356 -27.75337 36.75781  1.000 62.39271  ? 78  THR C N   1 
ATOM   5283 C CA  . THR C 1 118 ? -22.42243 -26.58120 36.69879  1.000 58.06953  ? 78  THR C CA  1 
ATOM   5284 C C   . THR C 1 118 ? -22.18099 -25.97017 38.07655  1.000 61.42249  ? 78  THR C C   1 
ATOM   5285 O O   . THR C 1 118 ? -21.03483 -25.71517 38.46328  1.000 68.37526  ? 78  THR C O   1 
ATOM   5286 C CB  . THR C 1 118 ? -23.02184 -25.53801 35.75279  1.000 67.19473  ? 78  THR C CB  1 
ATOM   5287 O OG1 . THR C 1 118 ? -23.15413 -26.09776 34.44007  1.000 58.44967  ? 78  THR C OG1 1 
ATOM   5288 C CG2 . THR C 1 118 ? -22.13357 -24.31156 35.68355  1.000 60.87418  ? 78  THR C CG2 1 
ATOM   5289 N N   . TYR C 1 119 ? -23.25608 -25.72779 38.83218  1.000 72.67825  ? 79  TYR C N   1 
ATOM   5290 C CA  . TYR C 1 119 ? -23.13720 -24.98216 40.08246  1.000 72.76644  ? 79  TYR C CA  1 
ATOM   5291 C C   . TYR C 1 119 ? -22.36436 -25.74801 41.15287  1.000 73.96312  ? 79  TYR C C   1 
ATOM   5292 O O   . TYR C 1 119 ? -21.72143 -25.12777 42.00764  1.000 69.84238  ? 79  TYR C O   1 
ATOM   5293 C CB  . TYR C 1 119 ? -24.53701 -24.62372 40.58877  1.000 79.54081  ? 79  TYR C CB  1 
ATOM   5294 C CG  . TYR C 1 119 ? -24.57293 -23.92679 41.93025  1.000 88.10456  ? 79  TYR C CG  1 
ATOM   5295 C CD1 . TYR C 1 119 ? -24.49183 -22.54400 42.01736  1.000 86.32136  ? 79  TYR C CD1 1 
ATOM   5296 C CD2 . TYR C 1 119 ? -24.70611 -24.65083 43.10905  1.000 80.80072  ? 79  TYR C CD2 1 
ATOM   5297 C CE1 . TYR C 1 119 ? -24.52920 -21.90217 43.24028  1.000 87.25919  ? 79  TYR C CE1 1 
ATOM   5298 C CE2 . TYR C 1 119 ? -24.74270 -24.01792 44.33605  1.000 89.18473  ? 79  TYR C CE2 1 
ATOM   5299 C CZ  . TYR C 1 119 ? -24.65464 -22.64350 44.39610  1.000 96.08483  ? 79  TYR C CZ  1 
ATOM   5300 O OH  . TYR C 1 119 ? -24.69227 -22.00787 45.61609  1.000 106.78521 ? 79  TYR C OH  1 
ATOM   5301 N N   . GLU C 1 120 ? -22.40034 -27.07857 41.12519  1.000 70.89915  ? 80  GLU C N   1 
ATOM   5302 C CA  . GLU C 1 120 ? -21.67065 -27.88846 42.09517  1.000 63.58579  ? 80  GLU C CA  1 
ATOM   5303 C C   . GLU C 1 120 ? -20.23592 -28.19412 41.68333  1.000 70.23814  ? 80  GLU C C   1 
ATOM   5304 O O   . GLU C 1 120 ? -19.46479 -28.68595 42.51455  1.000 73.90032  ? 80  GLU C O   1 
ATOM   5305 C CB  . GLU C 1 120 ? -22.41258 -29.20430 42.38162  1.000 68.58399  ? 80  GLU C CB  1 
ATOM   5306 C CG  . GLU C 1 120 ? -23.72489 -29.06620 43.16426  1.000 80.32164  ? 80  GLU C CG  1 
ATOM   5307 C CD  . GLU C 1 120 ? -24.79811 -28.27775 42.44070  1.000 84.19891  ? 80  GLU C CD  1 
ATOM   5308 O OE1 . GLU C 1 120 ? -24.74485 -28.19165 41.19645  1.000 85.19674  ? 80  GLU C OE1 1 
ATOM   5309 O OE2 . GLU C 1 120 ? -25.69682 -27.74090 43.12257  1.000 93.30986  ? 80  GLU C OE2 1 
ATOM   5310 N N   . THR C 1 121 ? -19.85363 -27.91075 40.44223  1.000 64.47997  ? 81  THR C N   1 
ATOM   5311 C CA  . THR C 1 121 ? -18.62047 -28.45666 39.88560  1.000 67.44787  ? 81  THR C CA  1 
ATOM   5312 C C   . THR C 1 121 ? -17.37539 -27.77658 40.45758  1.000 62.15951  ? 81  THR C C   1 
ATOM   5313 O O   . THR C 1 121 ? -16.41505 -28.47902 40.79896  1.000 67.91452  ? 81  THR C O   1 
ATOM   5314 C CB  . THR C 1 121 ? -18.63188 -28.35456 38.35620  1.000 69.65902  ? 81  THR C CB  1 
ATOM   5315 O OG1 . THR C 1 121 ? -19.72513 -29.11861 37.83395  1.000 62.30561  ? 81  THR C OG1 1 
ATOM   5316 C CG2 . THR C 1 121 ? -17.33332 -28.89013 37.77238  1.000 56.21396  ? 81  THR C CG2 1 
ATOM   5317 N N   . PRO C 1 122 ? -17.32321 -26.43966 40.57736  1.000 63.52441  ? 82  PRO C N   1 
ATOM   5318 C CA  . PRO C 1 122 ? -16.11154 -25.83199 41.15792  1.000 69.10654  ? 82  PRO C CA  1 
ATOM   5319 C C   . PRO C 1 122 ? -15.79271 -26.33725 42.55294  1.000 68.53221  ? 82  PRO C C   1 
ATOM   5320 O O   . PRO C 1 122 ? -14.61982 -26.56308 42.87266  1.000 67.19326  ? 82  PRO C O   1 
ATOM   5321 C CB  . PRO C 1 122 ? -16.43970 -24.33366 41.15638  1.000 54.71454  ? 82  PRO C CB  1 
ATOM   5322 C CG  . PRO C 1 122 ? -17.39862 -24.17453 40.04939  1.000 57.44924  ? 82  PRO C CG  1 
ATOM   5323 C CD  . PRO C 1 122 ? -18.25376 -25.39978 40.09814  1.000 59.24204  ? 82  PRO C CD  1 
ATOM   5324 N N   . ALA C 1 123 ? -16.80742 -26.51616 43.39960  1.000 64.98154  ? 83  ALA C N   1 
ATOM   5325 C CA  . ALA C 1 123 ? -16.55999 -27.02368 44.74443  1.000 56.98445  ? 83  ALA C CA  1 
ATOM   5326 C C   . ALA C 1 123 ? -16.03288 -28.45304 44.70725  1.000 65.49504  ? 83  ALA C C   1 
ATOM   5327 O O   . ALA C 1 123 ? -15.11415 -28.80404 45.45644  1.000 66.19549  ? 83  ALA C O   1 
ATOM   5328 C CB  . ALA C 1 123 ? -17.83815 -26.93868 45.57765  1.000 52.06193  ? 83  ALA C CB  1 
ATOM   5329 N N   . ILE C 1 124 ? -16.61193 -29.29600 43.85026  1.000 56.77303  ? 84  ILE C N   1 
ATOM   5330 C CA  . ILE C 1 124 ? -16.12483 -30.66518 43.70365  1.000 60.89067  ? 84  ILE C CA  1 
ATOM   5331 C C   . ILE C 1 124 ? -14.68701 -30.67729 43.19429  1.000 67.00162  ? 84  ILE C C   1 
ATOM   5332 O O   . ILE C 1 124 ? -13.85545 -31.46575 43.65988  1.000 61.46335  ? 84  ILE C O   1 
ATOM   5333 C CB  . ILE C 1 124 ? -17.06686 -31.46771 42.78616  1.000 62.95401  ? 84  ILE C CB  1 
ATOM   5334 C CG1 . ILE C 1 124 ? -18.44964 -31.59517 43.43163  1.000 59.76174  ? 84  ILE C CG1 1 
ATOM   5335 C CG2 . ILE C 1 124 ? -16.49482 -32.84262 42.49635  1.000 60.57608  ? 84  ILE C CG2 1 
ATOM   5336 C CD1 . ILE C 1 124 ? -19.47769 -32.28237 42.55430  1.000 62.56044  ? 84  ILE C CD1 1 
ATOM   5337 N N   . ALA C 1 125 ? -14.36971 -29.80664 42.23271  1.000 69.44301  ? 85  ALA C N   1 
ATOM   5338 C CA  . ALA C 1 125 ? -13.01630 -29.76616 41.68268  1.000 67.00577  ? 85  ALA C CA  1 
ATOM   5339 C C   . ALA C 1 125 ? -11.99647 -29.39519 42.75240  1.000 65.10600  ? 85  ALA C C   1 
ATOM   5340 O O   . ALA C 1 125 ? -10.98295 -30.08143 42.93115  1.000 64.32147  ? 85  ALA C O   1 
ATOM   5341 C CB  . ALA C 1 125 ? -12.95601 -28.77600 40.51855  1.000 64.09344  ? 85  ALA C CB  1 
ATOM   5342 N N   . LYS C 1 126 ? -12.25102 -28.29537 43.46237  1.000 60.81369  ? 86  LYS C N   1 
ATOM   5343 C CA  . LYS C 1 126 ? -11.37603 -27.84032 44.53828  1.000 67.48624  ? 86  LYS C CA  1 
ATOM   5344 C C   . LYS C 1 126 ? -11.17028 -28.92797 45.58572  1.000 74.11730  ? 86  LYS C C   1 
ATOM   5345 O O   . LYS C 1 126 ? -10.06941 -29.08891 46.12602  1.000 77.08942  ? 86  LYS C O   1 
ATOM   5346 C CB  . LYS C 1 126 ? -11.99447 -26.58218 45.14465  1.000 60.61481  ? 86  LYS C CB  1 
ATOM   5347 C CG  . LYS C 1 126 ? -11.97578 -25.43017 44.15540  1.000 66.27626  ? 86  LYS C CG  1 
ATOM   5348 C CD  . LYS C 1 126 ? -12.90720 -24.28678 44.52352  1.000 58.27129  ? 86  LYS C CD  1 
ATOM   5349 C CE  . LYS C 1 126 ? -12.51356 -23.55406 45.78161  1.000 61.96771  ? 86  LYS C CE  1 
ATOM   5350 N NZ  . LYS C 1 126 ? -13.36887 -22.33893 45.93335  1.000 72.22769  ? 86  LYS C NZ  1 
ATOM   5351 N N   . GLU C 1 127 ? -12.22954 -29.68011 45.88307  1.000 69.82806  ? 87  GLU C N   1 
ATOM   5352 C CA  . GLU C 1 127 ? -12.14730 -30.79049 46.82715  1.000 76.45017  ? 87  GLU C CA  1 
ATOM   5353 C C   . GLU C 1 127 ? -11.16325 -31.86154 46.35664  1.000 74.05125  ? 87  GLU C C   1 
ATOM   5354 O O   . GLU C 1 127 ? -10.34640 -32.35816 47.14129  1.000 67.87164  ? 87  GLU C O   1 
ATOM   5355 C CB  . GLU C 1 127 ? -13.55548 -31.35357 47.03583  1.000 75.61780  ? 87  GLU C CB  1 
ATOM   5356 C CG  . GLU C 1 127 ? -13.73740 -32.38666 48.13035  1.000 92.81658  ? 87  GLU C CG  1 
ATOM   5357 C CD  . GLU C 1 127 ? -15.19854 -32.51704 48.52392  1.000 122.37323 ? 87  GLU C CD  1 
ATOM   5358 O OE1 . GLU C 1 127 ? -15.79381 -31.51223 48.98113  1.000 124.08943 ? 87  GLU C OE1 1 
ATOM   5359 O OE2 . GLU C 1 127 ? -15.78530 -33.58331 48.24519  1.000 120.97335 ? 87  GLU C OE2 1 
ATOM   5360 N N   . LEU C 1 128 ? -11.22527 -32.23471 45.07673  1.000 73.54418  ? 88  LEU C N   1 
ATOM   5361 C CA  . LEU C 1 128 ? -10.37357 -33.31212 44.57653  1.000 63.52910  ? 88  LEU C CA  1 
ATOM   5362 C C   . LEU C 1 128 ? -8.96416  -32.83792 44.23778  1.000 72.48739  ? 88  LEU C C   1 
ATOM   5363 O O   . LEU C 1 128 ? -8.01106  -33.61264 44.37821  1.000 72.72742  ? 88  LEU C O   1 
ATOM   5364 C CB  . LEU C 1 128 ? -11.01293 -33.99028 43.36075  1.000 58.72465  ? 88  LEU C CB  1 
ATOM   5365 C CG  . LEU C 1 128 ? -12.16255 -34.98790 43.57423  1.000 69.58286  ? 88  LEU C CG  1 
ATOM   5366 C CD1 . LEU C 1 128 ? -13.30202 -34.44899 44.42826  1.000 82.58512  ? 88  LEU C CD1 1 
ATOM   5367 C CD2 . LEU C 1 128 ? -12.69134 -35.46675 42.23298  1.000 50.70478  ? 88  LEU C CD2 1 
ATOM   5368 N N   . LEU C 1 129 ? -8.81288  -31.59501 43.76715  1.000 69.68700  ? 89  LEU C N   1 
ATOM   5369 C CA  . LEU C 1 129 ? -7.47825  -31.04871 43.52839  1.000 72.63914  ? 89  LEU C CA  1 
ATOM   5370 C C   . LEU C 1 129 ? -6.62122  -31.09349 44.78770  1.000 74.36231  ? 89  LEU C C   1 
ATOM   5371 O O   . LEU C 1 129 ? -5.42673  -31.40747 44.72169  1.000 74.75676  ? 89  LEU C O   1 
ATOM   5372 C CB  . LEU C 1 129 ? -7.57443  -29.61480 43.00489  1.000 72.68078  ? 89  LEU C CB  1 
ATOM   5373 C CG  . LEU C 1 129 ? -8.11920  -29.40551 41.59146  1.000 65.14218  ? 89  LEU C CG  1 
ATOM   5374 C CD1 . LEU C 1 129 ? -8.41816  -27.93501 41.35349  1.000 58.15500  ? 89  LEU C CD1 1 
ATOM   5375 C CD2 . LEU C 1 129 ? -7.13946  -29.92317 40.55286  1.000 61.97537  ? 89  LEU C CD2 1 
ATOM   5376 N N   . ALA C 1 130 ? -7.20951  -30.76972 45.94260  1.000 71.57314  ? 90  ALA C N   1 
ATOM   5377 C CA  . ALA C 1 130 ? -6.45574  -30.74985 47.19150  1.000 70.42300  ? 90  ALA C CA  1 
ATOM   5378 C C   . ALA C 1 130 ? -5.90082  -32.12026 47.55186  1.000 73.55903  ? 90  ALA C C   1 
ATOM   5379 O O   . ALA C 1 130 ? -4.91270  -32.20338 48.29002  1.000 77.80043  ? 90  ALA C O   1 
ATOM   5380 C CB  . ALA C 1 130 ? -7.33299  -30.22655 48.32887  1.000 77.27716  ? 90  ALA C CB  1 
ATOM   5381 N N   . ARG C 1 131 ? -6.51370  -33.19087 47.05280  1.000 73.49519  ? 91  ARG C N   1 
ATOM   5382 C CA  . ARG C 1 131 ? -5.99436  -34.54156 47.21016  1.000 70.85485  ? 91  ARG C CA  1 
ATOM   5383 C C   . ARG C 1 131 ? -4.88682  -34.85915 46.21425  1.000 72.21530  ? 91  ARG C C   1 
ATOM   5384 O O   . ARG C 1 131 ? -4.43032  -36.00629 46.16122  1.000 73.75882  ? 91  ARG C O   1 
ATOM   5385 C CB  . ARG C 1 131 ? -7.12970  -35.55851 47.05986  1.000 70.40270  ? 91  ARG C CB  1 
ATOM   5386 C CG  . ARG C 1 131 ? -8.27663  -35.36090 48.03829  1.000 69.81338  ? 91  ARG C CG  1 
ATOM   5387 C CD  . ARG C 1 131 ? -9.18365  -36.58076 48.08956  1.000 69.42981  ? 91  ARG C CD  1 
ATOM   5388 N NE  . ARG C 1 131 ? -10.56145 -36.21766 48.39908  1.000 81.09558  ? 91  ARG C NE  1 
ATOM   5389 C CZ  . ARG C 1 131 ? -11.54226 -37.08880 48.59278  1.000 91.60246  ? 91  ARG C CZ  1 
ATOM   5390 N NH1 . ARG C 1 131 ? -11.33031 -38.39317 48.53200  1.000 89.10504  ? 91  ARG C NH1 1 
ATOM   5391 N NH2 . ARG C 1 131 ? -12.76572 -36.63982 48.85976  1.000 94.54304  ? 91  ARG C NH2 1 
ATOM   5392 N N   . GLY C 1 132 ? -4.45103  -33.87510 45.42946  1.000 66.41785  ? 92  GLY C N   1 
ATOM   5393 C CA  . GLY C 1 132 ? -3.44299  -34.10731 44.41661  1.000 67.30156  ? 92  GLY C CA  1 
ATOM   5394 C C   . GLY C 1 132 ? -3.96287  -34.75126 43.15511  1.000 64.65722  ? 92  GLY C C   1 
ATOM   5395 O O   . GLY C 1 132 ? -3.16669  -35.24290 42.34903  1.000 62.83584  ? 92  GLY C O   1 
ATOM   5396 N N   . ILE C 1 133 ? -5.27828  -34.75970 42.95486  1.000 66.17593  ? 93  ILE C N   1 
ATOM   5397 C CA  . ILE C 1 133 ? -5.90080  -35.37306 41.78815  1.000 66.51313  ? 93  ILE C CA  1 
ATOM   5398 C C   . ILE C 1 133 ? -6.19636  -34.29189 40.75964  1.000 65.50954  ? 93  ILE C C   1 
ATOM   5399 O O   . ILE C 1 133 ? -6.77408  -33.24764 41.08926  1.000 65.46305  ? 93  ILE C O   1 
ATOM   5400 C CB  . ILE C 1 133 ? -7.18480  -36.12588 42.17605  1.000 70.96489  ? 93  ILE C CB  1 
ATOM   5401 C CG1 . ILE C 1 133 ? -6.88682  -37.16975 43.25427  1.000 68.70600  ? 93  ILE C CG1 1 
ATOM   5402 C CG2 . ILE C 1 133 ? -7.81044  -36.78461 40.95351  1.000 66.87306  ? 93  ILE C CG2 1 
ATOM   5403 C CD1 . ILE C 1 133 ? -8.12362  -37.85873 43.79185  1.000 61.82985  ? 93  ILE C CD1 1 
ATOM   5404 N N   . HIS C 1 134 ? -5.80001  -34.54109 39.51571  1.000 58.34865  ? 94  HIS C N   1 
ATOM   5405 C CA  . HIS C 1 134 ? -6.14001  -33.64659 38.42114  1.000 60.91496  ? 94  HIS C CA  1 
ATOM   5406 C C   . HIS C 1 134 ? -7.64233  -33.68842 38.15646  1.000 60.99335  ? 94  HIS C C   1 
ATOM   5407 O O   . HIS C 1 134 ? -8.29951  -34.71475 38.35097  1.000 55.52965  ? 94  HIS C O   1 
ATOM   5408 C CB  . HIS C 1 134 ? -5.36573  -34.03836 37.16330  1.000 59.00247  ? 94  HIS C CB  1 
ATOM   5409 C CG  . HIS C 1 134 ? -3.89003  -34.17208 37.38282  1.000 69.41709  ? 94  HIS C CG  1 
ATOM   5410 N ND1 . HIS C 1 134 ? -3.18742  -33.35287 38.24057  1.000 69.36501  ? 94  HIS C ND1 1 
ATOM   5411 C CD2 . HIS C 1 134 ? -2.98528  -35.03502 36.86159  1.000 64.51606  ? 94  HIS C CD2 1 
ATOM   5412 C CE1 . HIS C 1 134 ? -1.91359  -33.70320 38.23602  1.000 58.74947  ? 94  HIS C CE1 1 
ATOM   5413 N NE2 . HIS C 1 134 ? -1.76420  -34.72107 37.40728  1.000 59.46051  ? 94  HIS C NE2 1 
ATOM   5414 N N   . THR C 1 135 ? -8.18955  -32.55647 37.71073  1.000 54.56140  ? 95  THR C N   1 
ATOM   5415 C CA  . THR C 1 135 ? -9.62055  -32.43538 37.46379  1.000 63.01290  ? 95  THR C CA  1 
ATOM   5416 C C   . THR C 1 135 ? -9.87672  -31.83752 36.08795  1.000 60.50181  ? 95  THR C C   1 
ATOM   5417 O O   . THR C 1 135 ? -9.22784  -30.86635 35.68742  1.000 54.40644  ? 95  THR C O   1 
ATOM   5418 C CB  . THR C 1 135 ? -10.31357 -31.56637 38.52849  1.000 62.69654  ? 95  THR C CB  1 
ATOM   5419 O OG1 . THR C 1 135 ? -9.78673  -30.23367 38.48602  1.000 64.39283  ? 95  THR C OG1 1 
ATOM   5420 C CG2 . THR C 1 135 ? -10.11454 -32.15400 39.92007  1.000 59.06395  ? 95  THR C CG2 1 
ATOM   5421 N N   . ILE C 1 136 ? -10.83435 -32.42239 35.37368  1.000 53.37315  ? 96  ILE C N   1 
ATOM   5422 C CA  . ILE C 1 136 ? -11.32935 -31.89551 34.10868  1.000 59.08476  ? 96  ILE C CA  1 
ATOM   5423 C C   . ILE C 1 136 ? -12.80640 -31.56814 34.27369  1.000 53.83977  ? 96  ILE C C   1 
ATOM   5424 O O   . ILE C 1 136 ? -13.56115 -32.35205 34.85961  1.000 61.61035  ? 96  ILE C O   1 
ATOM   5425 C CB  . ILE C 1 136 ? -11.12174 -32.89516 32.95088  1.000 59.43452  ? 96  ILE C CB  1 
ATOM   5426 C CG1 . ILE C 1 136 ? -9.68254  -33.41653 32.93551  1.000 53.65314  ? 96  ILE C CG1 1 
ATOM   5427 C CG2 . ILE C 1 136 ? -11.47984 -32.25130 31.61788  1.000 55.33861  ? 96  ILE C CG2 1 
ATOM   5428 C CD1 . ILE C 1 136 ? -8.64413  -32.35694 32.60595  1.000 64.84760  ? 96  ILE C CD1 1 
ATOM   5429 N N   . ASP C 1 137 ? -13.21873 -30.40965 33.76285  1.000 54.00027  ? 97  ASP C N   1 
ATOM   5430 C CA  . ASP C 1 137 ? -14.62667 -30.03916 33.76300  1.000 58.68128  ? 97  ASP C CA  1 
ATOM   5431 C C   . ASP C 1 137 ? -14.94587 -29.27659 32.48460  1.000 56.19328  ? 97  ASP C C   1 
ATOM   5432 O O   . ASP C 1 137 ? -14.05316 -28.79158 31.78523  1.000 59.36201  ? 97  ASP C O   1 
ATOM   5433 C CB  . ASP C 1 137 ? -15.00461 -29.21039 35.00583  1.000 48.96691  ? 97  ASP C CB  1 
ATOM   5434 C CG  . ASP C 1 137 ? -14.35825 -27.83465 35.02479  1.000 65.15646  ? 97  ASP C CG  1 
ATOM   5435 O OD1 . ASP C 1 137 ? -14.76590 -26.96652 34.22622  1.000 61.95719  ? 97  ASP C OD1 1 
ATOM   5436 O OD2 . ASP C 1 137 ? -13.44552 -27.62112 35.84870  1.000 76.44284  ? 97  ASP C OD2 1 
ATOM   5437 N N   . SER C 1 138 ? -16.23959 -29.18287 32.18555  1.000 62.56856  ? 98  SER C N   1 
ATOM   5438 C CA  . SER C 1 138 ? -16.75544 -28.43759 31.04299  1.000 58.86896  ? 98  SER C CA  1 
ATOM   5439 C C   . SER C 1 138 ? -17.66759 -27.30437 31.50082  1.000 58.09376  ? 98  SER C C   1 
ATOM   5440 O O   . SER C 1 138 ? -18.70904 -27.03648 30.89705  1.000 65.61963  ? 98  SER C O   1 
ATOM   5441 C CB  . SER C 1 138 ? -17.48574 -29.36282 30.07413  1.000 56.35320  ? 98  SER C CB  1 
ATOM   5442 O OG  . SER C 1 138 ? -18.48283 -30.10814 30.74808  1.000 58.09205  ? 98  SER C OG  1 
ATOM   5443 N N   . PHE C 1 139 ? -17.29100 -26.65558 32.60312  1.000 56.14912  ? 99  PHE C N   1 
ATOM   5444 C CA  . PHE C 1 139 ? -17.99378 -25.49171 33.13493  1.000 52.58679  ? 99  PHE C CA  1 
ATOM   5445 C C   . PHE C 1 139 ? -18.32216 -24.50026 32.02431  1.000 61.10990  ? 99  PHE C C   1 
ATOM   5446 O O   . PHE C 1 139 ? -17.44259 -24.09604 31.25992  1.000 61.87111  ? 99  PHE C O   1 
ATOM   5447 C CB  . PHE C 1 139 ? -17.11536 -24.83028 34.20097  1.000 51.79707  ? 99  PHE C CB  1 
ATOM   5448 C CG  . PHE C 1 139 ? -17.78956 -23.72827 34.96322  1.000 66.10321  ? 99  PHE C CG  1 
ATOM   5449 C CD1 . PHE C 1 139 ? -18.51687 -24.00789 36.10827  1.000 65.55463  ? 99  PHE C CD1 1 
ATOM   5450 C CD2 . PHE C 1 139 ? -17.68035 -22.41045 34.54942  1.000 63.68332  ? 99  PHE C CD2 1 
ATOM   5451 C CE1 . PHE C 1 139 ? -19.12840 -22.99398 36.82308  1.000 67.31348  ? 99  PHE C CE1 1 
ATOM   5452 C CE2 . PHE C 1 139 ? -18.29376 -21.39240 35.25857  1.000 67.54970  ? 99  PHE C CE2 1 
ATOM   5453 C CZ  . PHE C 1 139 ? -19.01941 -21.68561 36.39585  1.000 69.77879  ? 99  PHE C CZ  1 
ATOM   5454 N N   . ASP C 1 140 ? -19.60007 -24.10345 31.93872  1.000 61.90630  ? 100 ASP C N   1 
ATOM   5455 C CA  . ASP C 1 140 ? -20.09173 -23.40862 30.75219  1.000 67.47811  ? 100 ASP C CA  1 
ATOM   5456 C C   . ASP C 1 140 ? -20.74105 -22.06064 31.05607  1.000 53.82859  ? 100 ASP C C   1 
ATOM   5457 O O   . ASP C 1 140 ? -21.51200 -21.55834 30.23124  1.000 59.98386  ? 100 ASP C O   1 
ATOM   5458 C CB  . ASP C 1 140 ? -21.07918 -24.29203 29.98457  1.000 63.01164  ? 100 ASP C CB  1 
ATOM   5459 C CG  . ASP C 1 140 ? -22.24645 -24.74638 30.84002  1.000 63.02446  ? 100 ASP C CG  1 
ATOM   5460 O OD1 . ASP C 1 140 ? -22.35429 -24.30363 32.00464  1.000 59.84021  ? 100 ASP C OD1 1 
ATOM   5461 O OD2 . ASP C 1 140 ? -23.06383 -25.54757 30.34174  1.000 69.13727  ? 100 ASP C OD2 1 
ATOM   5462 N N   . ILE C 1 141 ? -20.45927 -21.46003 32.20935  1.000 54.74385  ? 101 ILE C N   1 
ATOM   5463 C CA  . ILE C 1 141 ? -20.90648 -20.09924 32.49253  1.000 61.26444  ? 101 ILE C CA  1 
ATOM   5464 C C   . ILE C 1 141 ? -19.75269 -19.17397 32.11879  1.000 53.97561  ? 101 ILE C C   1 
ATOM   5465 O O   . ILE C 1 141 ? -18.79963 -19.01104 32.88163  1.000 55.94871  ? 101 ILE C O   1 
ATOM   5466 C CB  . ILE C 1 141 ? -21.33860 -19.92029 33.94792  1.000 64.42117  ? 101 ILE C CB  1 
ATOM   5467 C CG1 . ILE C 1 141 ? -22.46781 -20.89601 34.29066  1.000 64.56494  ? 101 ILE C CG1 1 
ATOM   5468 C CG2 . ILE C 1 141 ? -21.80431 -18.49266 34.18454  1.000 60.10869  ? 101 ILE C CG2 1 
ATOM   5469 C CD1 . ILE C 1 141 ? -22.97440 -20.76759 35.71031  1.000 67.06354  ? 101 ILE C CD1 1 
ATOM   5470 N N   . HIS C 1 142 ? -19.83986 -18.57711 30.92540  1.000 57.86435  ? 102 HIS C N   1 
ATOM   5471 C CA  . HIS C 1 142 ? -18.72112 -17.81451 30.37698  1.000 60.03263  ? 102 HIS C CA  1 
ATOM   5472 C C   . HIS C 1 142 ? -18.30686 -16.67394 31.29831  1.000 59.23187  ? 102 HIS C C   1 
ATOM   5473 O O   . HIS C 1 142 ? -17.11131 -16.40599 31.46462  1.000 73.52631  ? 102 HIS C O   1 
ATOM   5474 C CB  . HIS C 1 142 ? -19.08330 -17.27353 28.99195  1.000 47.42109  ? 102 HIS C CB  1 
ATOM   5475 C CG  . HIS C 1 142 ? -19.27991 -18.34004 27.96083  1.000 61.76654  ? 102 HIS C CG  1 
ATOM   5476 N ND1 . HIS C 1 142 ? -18.23110 -18.92065 27.28081  1.000 68.79679  ? 102 HIS C ND1 1 
ATOM   5477 C CD2 . HIS C 1 142 ? -20.40528 -18.92179 27.48390  1.000 64.07089  ? 102 HIS C CD2 1 
ATOM   5478 C CE1 . HIS C 1 142 ? -18.70035 -19.82679 26.44208  1.000 63.52012  ? 102 HIS C CE1 1 
ATOM   5479 N NE2 . HIS C 1 142 ? -20.01726 -19.84288 26.54143  1.000 73.32350  ? 102 HIS C NE2 1 
ATOM   5480 N N   . GLN C 1 143 ? -19.27820 -15.98417 31.89922  1.000 54.33898  ? 103 GLN C N   1 
ATOM   5481 C CA  . GLN C 1 143 ? -18.96215 -14.81212 32.70599  1.000 59.54616  ? 103 GLN C CA  1 
ATOM   5482 C C   . GLN C 1 143 ? -18.21266 -15.16071 33.98678  1.000 64.74666  ? 103 GLN C C   1 
ATOM   5483 O O   . GLN C 1 143 ? -17.62779 -14.26632 34.60708  1.000 69.47860  ? 103 GLN C O   1 
ATOM   5484 C CB  . GLN C 1 143 ? -20.24130 -14.04678 33.04521  1.000 71.72671  ? 103 GLN C CB  1 
ATOM   5485 C CG  . GLN C 1 143 ? -20.06574 -12.53855 33.01407  1.000 95.37507  ? 103 GLN C CG  1 
ATOM   5486 C CD  . GLN C 1 143 ? -20.62201 -11.86106 34.24691  1.000 106.18656 ? 103 GLN C CD  1 
ATOM   5487 O OE1 . GLN C 1 143 ? -21.50755 -12.39338 34.91579  1.000 109.96272 ? 103 GLN C OE1 1 
ATOM   5488 N NE2 . GLN C 1 143 ? -20.09794 -10.68227 34.56048  1.000 92.42777  ? 103 GLN C NE2 1 
ATOM   5489 N N   . GLU C 1 144 ? -18.21530 -16.42816 34.39781  1.000 63.77757  ? 104 GLU C N   1 
ATOM   5490 C CA  . GLU C 1 144 ? -17.57322 -16.84683 35.63587  1.000 62.13755  ? 104 GLU C CA  1 
ATOM   5491 C C   . GLU C 1 144 ? -16.28744 -17.63195 35.41387  1.000 62.72416  ? 104 GLU C C   1 
ATOM   5492 O O   . GLU C 1 144 ? -15.68057 -18.08365 36.39038  1.000 64.11654  ? 104 GLU C O   1 
ATOM   5493 C CB  . GLU C 1 144 ? -18.54975 -17.68507 36.47057  1.000 60.62657  ? 104 GLU C CB  1 
ATOM   5494 C CG  . GLU C 1 144 ? -19.72788 -16.89114 37.01612  1.000 60.92385  ? 104 GLU C CG  1 
ATOM   5495 C CD  . GLU C 1 144 ? -20.78700 -17.77060 37.65533  1.000 77.86690  ? 104 GLU C CD  1 
ATOM   5496 O OE1 . GLU C 1 144 ? -20.45474 -18.89700 38.08002  1.000 71.41557  ? 104 GLU C OE1 1 
ATOM   5497 O OE2 . GLU C 1 144 ? -21.95580 -17.33503 37.73008  1.000 83.84561  ? 104 GLU C OE2 1 
ATOM   5498 N N   . ILE C 1 145 ? -15.85177 -17.80427 34.16454  1.000 62.66146  ? 105 ILE C N   1 
ATOM   5499 C CA  . ILE C 1 145 ? -14.70135 -18.66244 33.89080  1.000 59.80257  ? 105 ILE C CA  1 
ATOM   5500 C C   . ILE C 1 145 ? -13.42210 -18.04532 34.44746  1.000 60.81056  ? 105 ILE C C   1 
ATOM   5501 O O   . ILE C 1 145 ? -12.61746 -18.72895 35.09243  1.000 57.53062  ? 105 ILE C O   1 
ATOM   5502 C CB  . ILE C 1 145 ? -14.59197 -18.94617 32.38230  1.000 61.03571  ? 105 ILE C CB  1 
ATOM   5503 C CG1 . ILE C 1 145 ? -15.69065 -19.92328 31.95546  1.000 51.19104  ? 105 ILE C CG1 1 
ATOM   5504 C CG2 . ILE C 1 145 ? -13.21223 -19.48500 32.03159  1.000 52.33749  ? 105 ILE C CG2 1 
ATOM   5505 C CD1 . ILE C 1 145 ? -15.67742 -20.25412 30.48518  1.000 53.87080  ? 105 ILE C CD1 1 
ATOM   5506 N N   . VAL C 1 146 ? -13.21061 -16.74941 34.19601  1.000 58.58441  ? 106 VAL C N   1 
ATOM   5507 C CA  . VAL C 1 146 ? -12.03280 -16.06001 34.72326  1.000 53.62309  ? 106 VAL C CA  1 
ATOM   5508 C C   . VAL C 1 146 ? -11.96062 -16.21809 36.23726  1.000 56.83957  ? 106 VAL C C   1 
ATOM   5509 O O   . VAL C 1 146 ? -10.90427 -16.53111 36.80037  1.000 58.51432  ? 106 VAL C O   1 
ATOM   5510 C CB  . VAL C 1 146 ? -12.04583 -14.57670 34.30815  1.000 53.21205  ? 106 VAL C CB  1 
ATOM   5511 C CG1 . VAL C 1 146 ? -10.99250 -13.79900 35.07501  1.000 49.00822  ? 106 VAL C CG1 1 
ATOM   5512 C CG2 . VAL C 1 146 ? -11.81587 -14.43674 32.80766  1.000 54.15122  ? 106 VAL C CG2 1 
ATOM   5513 N N   . GLN C 1 147 ? -13.08763 -16.00008 36.91655  1.000 60.47753  ? 107 GLN C N   1 
ATOM   5514 C CA  . GLN C 1 147 ? -13.11886 -16.10254 38.37091  1.000 56.66053  ? 107 GLN C CA  1 
ATOM   5515 C C   . GLN C 1 147 ? -12.86097 -17.53559 38.83119  1.000 65.73118  ? 107 GLN C C   1 
ATOM   5516 O O   . GLN C 1 147 ? -12.04302 -17.77134 39.72776  1.000 62.47960  ? 107 GLN C O   1 
ATOM   5517 C CB  . GLN C 1 147 ? -14.46462 -15.59263 38.88953  1.000 52.25680  ? 107 GLN C CB  1 
ATOM   5518 C CG  . GLN C 1 147 ? -14.36996 -14.74919 40.14645  1.000 80.71014  ? 107 GLN C CG  1 
ATOM   5519 C CD  . GLN C 1 147 ? -14.09243 -15.57677 41.38013  1.000 87.00105  ? 107 GLN C CD  1 
ATOM   5520 O OE1 . GLN C 1 147 ? -13.02196 -15.48020 41.98041  1.000 92.48583  ? 107 GLN C OE1 1 
ATOM   5521 N NE2 . GLN C 1 147 ? -15.06065 -16.39729 41.76964  1.000 90.58626  ? 107 GLN C NE2 1 
ATOM   5522 N N   . VAL C 1 148 ? -13.55286 -18.50797 38.23004  1.000 56.88343  ? 108 VAL C N   1 
ATOM   5523 C CA  . VAL C 1 148 ? -13.37569 -19.90711 38.61927  1.000 58.17307  ? 108 VAL C CA  1 
ATOM   5524 C C   . VAL C 1 148 ? -11.95530 -20.37927 38.33257  1.000 63.18706  ? 108 VAL C C   1 
ATOM   5525 O O   . VAL C 1 148 ? -11.36988 -21.14081 39.11414  1.000 56.27551  ? 108 VAL C O   1 
ATOM   5526 C CB  . VAL C 1 148 ? -14.41760 -20.79423 37.91379  1.000 60.34797  ? 108 VAL C CB  1 
ATOM   5527 C CG1 . VAL C 1 148 ? -14.07718 -22.27007 38.09739  1.000 50.35023  ? 108 VAL C CG1 1 
ATOM   5528 C CG2 . VAL C 1 148 ? -15.80831 -20.50238 38.45537  1.000 67.09361  ? 108 VAL C CG2 1 
ATOM   5529 N N   . ARG C 1 149 ? -11.37685 -19.93343 37.21442  1.000 61.08147  ? 109 ARG C N   1 
ATOM   5530 C CA  . ARG C 1 149 ? -10.01154 -20.32681 36.87880  1.000 63.07321  ? 109 ARG C CA  1 
ATOM   5531 C C   . ARG C 1 149 ? -9.04169  -19.92583 37.98156  1.000 64.31359  ? 109 ARG C C   1 
ATOM   5532 O O   . ARG C 1 149 ? -8.17995  -20.71542 38.38525  1.000 61.07953  ? 109 ARG C O   1 
ATOM   5533 C CB  . ARG C 1 149 ? -9.58736  -19.70319 35.54918  1.000 63.79047  ? 109 ARG C CB  1 
ATOM   5534 C CG  . ARG C 1 149 ? -8.19681  -20.12666 35.11503  1.000 50.19112  ? 109 ARG C CG  1 
ATOM   5535 C CD  . ARG C 1 149 ? -7.70351  -19.34067 33.91777  1.000 56.40038  ? 109 ARG C CD  1 
ATOM   5536 N NE  . ARG C 1 149 ? -6.25924  -19.48026 33.77367  1.000 69.63436  ? 109 ARG C NE  1 
ATOM   5537 C CZ  . ARG C 1 149 ? -5.37126  -18.75132 34.43622  1.000 63.49743  ? 109 ARG C CZ  1 
ATOM   5538 N NH1 . ARG C 1 149 ? -5.74691  -17.82820 35.30633  1.000 62.46459  ? 109 ARG C NH1 1 
ATOM   5539 N NH2 . ARG C 1 149 ? -4.07431  -18.96143 34.22969  1.000 75.15350  ? 109 ARG C NH2 1 
ATOM   5540 N N   . HIS C 1 150 ? -9.16114  -18.68963 38.47120  1.000 59.53964  ? 110 HIS C N   1 
ATOM   5541 C CA  . HIS C 1 150 ? -8.29816  -18.23451 39.55555  1.000 55.13786  ? 110 HIS C CA  1 
ATOM   5542 C C   . HIS C 1 150 ? -8.50098  -19.07240 40.81195  1.000 61.18304  ? 110 HIS C C   1 
ATOM   5543 O O   . HIS C 1 150 ? -7.53065  -19.42975 41.48996  1.000 58.90897  ? 110 HIS C O   1 
ATOM   5544 C CB  . HIS C 1 150 ? -8.55265  -16.75559 39.84338  1.000 56.10790  ? 110 HIS C CB  1 
ATOM   5545 C CG  . HIS C 1 150 ? -7.90119  -15.83058 38.86272  1.000 64.26154  ? 110 HIS C CG  1 
ATOM   5546 N ND1 . HIS C 1 150 ? -6.58876  -15.97176 38.46578  1.000 69.68930  ? 110 HIS C ND1 1 
ATOM   5547 C CD2 . HIS C 1 150 ? -8.38195  -14.75420 38.19588  1.000 64.24202  ? 110 HIS C CD2 1 
ATOM   5548 C CE1 . HIS C 1 150 ? -6.28913  -15.02220 37.59724  1.000 64.11528  ? 110 HIS C CE1 1 
ATOM   5549 N NE2 . HIS C 1 150 ? -7.35977  -14.27002 37.41592  1.000 58.85304  ? 110 HIS C NE2 1 
ATOM   5550 N N   . GLU C 1 151 ? -9.75591  -19.39458 41.14124  1.000 68.59453  ? 111 GLU C N   1 
ATOM   5551 C CA  . GLU C 1 151 ? -10.02199 -20.17204 42.34834  1.000 59.65094  ? 111 GLU C CA  1 
ATOM   5552 C C   . GLU C 1 151 ? -9.45560  -21.58273 42.23802  1.000 56.52894  ? 111 GLU C C   1 
ATOM   5553 O O   . GLU C 1 151 ? -8.86514  -22.09466 43.19678  1.000 59.65950  ? 111 GLU C O   1 
ATOM   5554 C CB  . GLU C 1 151 ? -11.52286 -20.21264 42.63617  1.000 58.84087  ? 111 GLU C CB  1 
ATOM   5555 C CG  . GLU C 1 151 ? -12.15125 -18.84956 42.88448  1.000 60.39418  ? 111 GLU C CG  1 
ATOM   5556 C CD  . GLU C 1 151 ? -13.62631 -18.94652 43.22246  1.000 87.71288  ? 111 GLU C CD  1 
ATOM   5557 O OE1 . GLU C 1 151 ? -14.11158 -20.07381 43.45425  1.000 100.19528 ? 111 GLU C OE1 1 
ATOM   5558 O OE2 . GLU C 1 151 ? -14.29766 -17.89723 43.27821  1.000 89.52484  ? 111 GLU C OE2 1 
ATOM   5559 N N   . LEU C 1 152 ? -9.62763  -22.22990 41.08160  1.000 55.19606  ? 112 LEU C N   1 
ATOM   5560 C CA  . LEU C 1 152 ? -9.02343  -23.54380 40.88342  1.000 61.25545  ? 112 LEU C CA  1 
ATOM   5561 C C   . LEU C 1 152 ? -7.50477  -23.45755 40.83338  1.000 58.04542  ? 112 LEU C C   1 
ATOM   5562 O O   . LEU C 1 152 ? -6.81764  -24.39177 41.26135  1.000 61.63006  ? 112 LEU C O   1 
ATOM   5563 C CB  . LEU C 1 152 ? -9.54745  -24.18833 39.59949  1.000 60.27440  ? 112 LEU C CB  1 
ATOM   5564 C CG  . LEU C 1 152 ? -11.04849 -24.43541 39.47336  1.000 68.92602  ? 112 LEU C CG  1 
ATOM   5565 C CD1 . LEU C 1 152 ? -11.33231 -25.32205 38.27303  1.000 59.58010  ? 112 LEU C CD1 1 
ATOM   5566 C CD2 . LEU C 1 152 ? -11.58154 -25.06879 40.73571  1.000 57.59213  ? 112 LEU C CD2 1 
ATOM   5567 N N   . ASP C 1 153 ? -6.97095  -22.35439 40.30365  1.000 56.73792  ? 113 ASP C N   1 
ATOM   5568 C CA  . ASP C 1 153 ? -5.52509  -22.19145 40.19325  1.000 60.26531  ? 113 ASP C CA  1 
ATOM   5569 C C   . ASP C 1 153 ? -4.85026  -22.24208 41.55916  1.000 65.15898  ? 113 ASP C C   1 
ATOM   5570 O O   . ASP C 1 153 ? -3.80674  -22.88598 41.71897  1.000 69.40550  ? 113 ASP C O   1 
ATOM   5571 C CB  . ASP C 1 153 ? -5.20854  -20.87983 39.47306  1.000 55.36317  ? 113 ASP C CB  1 
ATOM   5572 C CG  . ASP C 1 153 ? -3.75888  -20.78156 39.04446  1.000 66.26379  ? 113 ASP C CG  1 
ATOM   5573 O OD1 . ASP C 1 153 ? -3.26296  -21.72278 38.39003  1.000 64.20415  ? 113 ASP C OD1 1 
ATOM   5574 O OD2 . ASP C 1 153 ? -3.11862  -19.75280 39.35005  1.000 76.39498  ? 113 ASP C OD2 1 
ATOM   5575 N N   . GLU C 1 154 ? -5.43213  -21.57308 42.55778  1.000 64.79505  ? 114 GLU C N   1 
ATOM   5576 C CA  . GLU C 1 154 ? -4.79162  -21.49866 43.86764  1.000 70.95617  ? 114 GLU C CA  1 
ATOM   5577 C C   . GLU C 1 154 ? -4.72444  -22.86843 44.53434  1.000 67.74417  ? 114 GLU C C   1 
ATOM   5578 O O   . GLU C 1 154 ? -3.71097  -23.21338 45.15280  1.000 77.48117  ? 114 GLU C O   1 
ATOM   5579 C CB  . GLU C 1 154 ? -5.53405  -20.50065 44.75752  1.000 71.16182  ? 114 GLU C CB  1 
ATOM   5580 C CG  . GLU C 1 154 ? -5.66265  -19.10647 44.15816  1.000 80.87157  ? 114 GLU C CG  1 
ATOM   5581 C CD  . GLU C 1 154 ? -6.36171  -18.13463 45.08920  1.000 100.72786 ? 114 GLU C CD  1 
ATOM   5582 O OE1 . GLU C 1 154 ? -6.63476  -18.51408 46.24643  1.000 103.64886 ? 114 GLU C OE1 1 
ATOM   5583 O OE2 . GLU C 1 154 ? -6.63814  -16.99274 44.66563  1.000 100.51004 ? 114 GLU C OE2 1 
ATOM   5584 N N   . VAL C 1 155 ? -5.79235  -23.66006 44.42561  1.000 59.81471  ? 115 VAL C N   1 
ATOM   5585 C CA  . VAL C 1 155 ? -5.77960  -25.00432 44.99391  1.000 62.30641  ? 115 VAL C CA  1 
ATOM   5586 C C   . VAL C 1 155 ? -4.82480  -25.90570 44.22071  1.000 66.64635  ? 115 VAL C C   1 
ATOM   5587 O O   . VAL C 1 155 ? -4.06810  -26.68642 44.81155  1.000 73.28570  ? 115 VAL C O   1 
ATOM   5588 C CB  . VAL C 1 155 ? -7.20531  -25.58275 45.01921  1.000 51.96748  ? 115 VAL C CB  1 
ATOM   5589 C CG1 . VAL C 1 155 ? -7.22643  -26.90353 45.77073  1.000 60.15747  ? 115 VAL C CG1 1 
ATOM   5590 C CG2 . VAL C 1 155 ? -8.17091  -24.58485 45.64183  1.000 50.42864  ? 115 VAL C CG2 1 
ATOM   5591 N N   . ALA C 1 156 ? -4.85621  -25.82202 42.88865  1.000 60.29835  ? 116 ALA C N   1 
ATOM   5592 C CA  . ALA C 1 156 ? -4.03518  -26.69624 42.05491  1.000 68.71800  ? 116 ALA C CA  1 
ATOM   5593 C C   . ALA C 1 156 ? -2.54366  -26.45964 42.27908  1.000 75.73184  ? 116 ALA C C   1 
ATOM   5594 O O   . ALA C 1 156 ? -1.76563  -27.41346 42.39809  1.000 64.25185  ? 116 ALA C O   1 
ATOM   5595 C CB  . ALA C 1 156 ? -4.39873  -26.50074 40.58208  1.000 56.26398  ? 116 ALA C CB  1 
ATOM   5596 N N   . ARG C 1 157 ? -2.12375  -25.19117 42.33529  1.000 68.16208  ? 117 ARG C N   1 
ATOM   5597 C CA  . ARG C 1 157 ? -0.70283  -24.89012 42.49791  1.000 62.55135  ? 117 ARG C CA  1 
ATOM   5598 C C   . ARG C 1 157 ? -0.17559  -25.37432 43.84203  1.000 71.35024  ? 117 ARG C C   1 
ATOM   5599 O O   . ARG C 1 157 ? 0.95957   -25.85579 43.93670  1.000 72.24434  ? 117 ARG C O   1 
ATOM   5600 C CB  . ARG C 1 157 ? -0.46775  -23.38437 42.37397  1.000 67.07273  ? 117 ARG C CB  1 
ATOM   5601 C CG  . ARG C 1 157 ? -0.66574  -22.79576 40.99092  1.000 73.80765  ? 117 ARG C CG  1 
ATOM   5602 C CD  . ARG C 1 157 ? -1.08622  -21.33462 41.10386  1.000 85.72923  ? 117 ARG C CD  1 
ATOM   5603 N NE  . ARG C 1 157 ? -1.11686  -20.88756 42.49230  1.000 74.35782  ? 117 ARG C NE  1 
ATOM   5604 C CZ  . ARG C 1 157 ? -1.24154  -19.62499 42.87900  1.000 85.55607  ? 117 ARG C CZ  1 
ATOM   5605 N NH1 . ARG C 1 157 ? -1.35106  -18.64011 42.00271  1.000 78.25271  ? 117 ARG C NH1 1 
ATOM   5606 N NH2 . ARG C 1 157 ? -1.24562  -19.34292 44.17902  1.000 82.84794  ? 117 ARG C NH2 1 
ATOM   5607 N N   . ALA C 1 158 ? -0.98858  -25.25805 44.89215  1.000 67.18810  ? 118 ALA C N   1 
ATOM   5608 C CA  . ALA C 1 158 ? -0.56682  -25.65049 46.23087  1.000 72.97442  ? 118 ALA C CA  1 
ATOM   5609 C C   . ALA C 1 158 ? -0.42028  -27.15668 46.39744  1.000 72.38584  ? 118 ALA C C   1 
ATOM   5610 O O   . ALA C 1 158 ? 0.27862   -27.59875 47.31635  1.000 86.45532  ? 118 ALA C O   1 
ATOM   5611 C CB  . ALA C 1 158 ? -1.55919  -25.11640 47.26492  1.000 74.17603  ? 118 ALA C CB  1 
ATOM   5612 N N   . HIS C 1 159 ? -1.05502  -27.95519 45.53975  1.000 75.52316  ? 119 HIS C N   1 
ATOM   5613 C CA  . HIS C 1 159 ? -1.15548  -29.38798 45.78758  1.000 77.11129  ? 119 HIS C CA  1 
ATOM   5614 C C   . HIS C 1 159 ? -0.67722  -30.22877 44.60818  1.000 71.22996  ? 119 HIS C C   1 
ATOM   5615 O O   . HIS C 1 159 ? -1.09115  -31.38260 44.46717  1.000 67.31222  ? 119 HIS C O   1 
ATOM   5616 C CB  . HIS C 1 159 ? -2.59451  -29.75402 46.15309  1.000 68.82455  ? 119 HIS C CB  1 
ATOM   5617 C CG  . HIS C 1 159 ? -3.08276  -29.09508 47.40616  1.000 77.37153  ? 119 HIS C CG  1 
ATOM   5618 N ND1 . HIS C 1 159 ? -3.72232  -27.87350 47.40609  1.000 74.45653  ? 119 HIS C ND1 1 
ATOM   5619 C CD2 . HIS C 1 159 ? -3.01514  -29.48391 48.70099  1.000 78.80604  ? 119 HIS C CD2 1 
ATOM   5620 C CE1 . HIS C 1 159 ? -4.03291  -27.54168 48.64649  1.000 75.11280  ? 119 HIS C CE1 1 
ATOM   5621 N NE2 . HIS C 1 159 ? -3.61516  -28.50209 49.45121  1.000 82.66258  ? 119 HIS C NE2 1 
ATOM   5622 N N   . GLN C 1 160 ? 0.19535   -29.67685 43.76228  1.000 63.64608  ? 120 GLN C N   1 
ATOM   5623 C CA  . GLN C 1 160 ? 0.78750   -30.42580 42.64920  1.000 71.65033  ? 120 GLN C CA  1 
ATOM   5624 C C   . GLN C 1 160 ? -0.27806  -31.06150 41.75948  1.000 65.23367  ? 120 GLN C C   1 
ATOM   5625 O O   . GLN C 1 160 ? -0.16262  -32.21781 41.34656  1.000 67.26830  ? 120 GLN C O   1 
ATOM   5626 C CB  . GLN C 1 160 ? 1.76163   -31.49405 43.15678  1.000 64.26553  ? 120 GLN C CB  1 
ATOM   5627 C CG  . GLN C 1 160 ? 3.11703   -30.97500 43.59282  1.000 71.93250  ? 120 GLN C CG  1 
ATOM   5628 C CD  . GLN C 1 160 ? 4.13349   -31.02239 42.46888  1.000 96.64613  ? 120 GLN C CD  1 
ATOM   5629 O OE1 . GLN C 1 160 ? 4.59269   -32.09660 42.08071  1.000 93.62426  ? 120 GLN C OE1 1 
ATOM   5630 N NE2 . GLN C 1 160 ? 4.48599   -29.85883 41.93600  1.000 91.33341  ? 120 GLN C NE2 1 
ATOM   5631 N N   . ALA C 1 161 ? -1.32448  -30.30100 41.45269  1.000 61.38568  ? 121 ALA C N   1 
ATOM   5632 C CA  . ALA C 1 161 ? -2.41595  -30.80274 40.63509  1.000 66.88492  ? 121 ALA C CA  1 
ATOM   5633 C C   . ALA C 1 161 ? -2.64124  -29.87589 39.45033  1.000 61.60724  ? 121 ALA C C   1 
ATOM   5634 O O   . ALA C 1 161 ? -2.25607  -28.70440 39.46616  1.000 61.47929  ? 121 ALA C O   1 
ATOM   5635 C CB  . ALA C 1 161 ? -3.70869  -30.94417 41.45040  1.000 69.35294  ? 121 ALA C CB  1 
ATOM   5636 N N   . VAL C 1 162 ? -3.27893  -30.41972 38.41812  1.000 53.45453  ? 122 VAL C N   1 
ATOM   5637 C CA  . VAL C 1 162 ? -3.59920  -29.68366 37.20292  1.000 60.50562  ? 122 VAL C CA  1 
ATOM   5638 C C   . VAL C 1 162 ? -5.10728  -29.72517 37.00947  1.000 63.05076  ? 122 VAL C C   1 
ATOM   5639 O O   . VAL C 1 162 ? -5.70696  -30.80617 36.99495  1.000 71.93308  ? 122 VAL C O   1 
ATOM   5640 C CB  . VAL C 1 162 ? -2.87137  -30.26413 35.97648  1.000 57.09501  ? 122 VAL C CB  1 
ATOM   5641 C CG1 . VAL C 1 162 ? -3.30437  -29.53844 34.71197  1.000 58.76652  ? 122 VAL C CG1 1 
ATOM   5642 C CG2 . VAL C 1 162 ? -1.36240  -30.17118 36.15998  1.000 48.27434  ? 122 VAL C CG2 1 
ATOM   5643 N N   . ALA C 1 163 ? -5.71460  -28.55420 36.84984  1.000 49.35689  ? 123 ALA C N   1 
ATOM   5644 C CA  . ALA C 1 163 ? -7.13592  -28.43674 36.56029  1.000 57.09249  ? 123 ALA C CA  1 
ATOM   5645 C C   . ALA C 1 163 ? -7.31739  -27.79425 35.19356  1.000 56.75416  ? 123 ALA C C   1 
ATOM   5646 O O   . ALA C 1 163 ? -6.75916  -26.72605 34.92617  1.000 54.86810  ? 123 ALA C O   1 
ATOM   5647 C CB  . ALA C 1 163 ? -7.85480  -27.61938 37.63765  1.000 56.04352  ? 123 ALA C CB  1 
ATOM   5648 N N   . ILE C 1 164 ? -8.08509  -28.44954 34.32976  1.000 55.20957  ? 124 ILE C N   1 
ATOM   5649 C CA  . ILE C 1 164 ? -8.50474  -27.88339 33.05399  1.000 56.75348  ? 124 ILE C CA  1 
ATOM   5650 C C   . ILE C 1 164 ? -10.01243 -27.68899 33.11425  1.000 60.14075  ? 124 ILE C C   1 
ATOM   5651 O O   . ILE C 1 164 ? -10.76444 -28.65985 33.26743  1.000 66.73535  ? 124 ILE C O   1 
ATOM   5652 C CB  . ILE C 1 164 ? -8.10266  -28.78047 31.87497  1.000 64.05211  ? 124 ILE C CB  1 
ATOM   5653 C CG1 . ILE C 1 164 ? -6.58148  -28.90027 31.80257  1.000 58.37837  ? 124 ILE C CG1 1 
ATOM   5654 C CG2 . ILE C 1 164 ? -8.66671  -28.23406 30.57296  1.000 47.16731  ? 124 ILE C CG2 1 
ATOM   5655 C CD1 . ILE C 1 164 ? -6.10474  -29.98523 30.87486  1.000 49.37899  ? 124 ILE C CD1 1 
ATOM   5656 N N   . LEU C 1 165 ? -10.45605 -26.44270 32.98314  1.000 52.38658  ? 125 LEU C N   1 
ATOM   5657 C CA  . LEU C 1 165 ? -11.86178 -26.09800 33.12327  1.000 58.16261  ? 125 LEU C CA  1 
ATOM   5658 C C   . LEU C 1 165 ? -12.41790 -25.59990 31.79650  1.000 62.60704  ? 125 LEU C C   1 
ATOM   5659 O O   . LEU C 1 165 ? -11.67518 -25.18709 30.90164  1.000 53.90107  ? 125 LEU C O   1 
ATOM   5660 C CB  . LEU C 1 165 ? -12.06913 -25.02767 34.20321  1.000 60.58732  ? 125 LEU C CB  1 
ATOM   5661 C CG  . LEU C 1 165 ? -11.67056 -23.58693 33.86708  1.000 63.87584  ? 125 LEU C CG  1 
ATOM   5662 C CD1 . LEU C 1 165 ? -12.42764 -22.60486 34.75243  1.000 53.90127  ? 125 LEU C CD1 1 
ATOM   5663 C CD2 . LEU C 1 165 ? -10.17020 -23.37472 33.99724  1.000 64.24141  ? 125 LEU C CD2 1 
ATOM   5664 N N   . ALA C 1 166 ? -13.74568 -25.66426 31.67674  1.000 52.22488  ? 126 ALA C N   1 
ATOM   5665 C CA  . ALA C 1 166 ? -14.45800 -25.19120 30.49098  1.000 46.35838  ? 126 ALA C CA  1 
ATOM   5666 C C   . ALA C 1 166 ? -14.00335 -25.92636 29.23419  1.000 53.12439  ? 126 ALA C C   1 
ATOM   5667 O O   . ALA C 1 166 ? -13.95673 -25.35223 28.14347  1.000 61.04038  ? 126 ALA C O   1 
ATOM   5668 C CB  . ALA C 1 166 ? -14.30748 -23.67645 30.31733  1.000 45.86367  ? 126 ALA C CB  1 
ATOM   5669 N N   . ALA C 1 167 ? -13.66834 -27.20469 29.37797  1.000 53.25397  ? 127 ALA C N   1 
ATOM   5670 C CA  . ALA C 1 167 ? -13.09294 -27.97937 28.28328  1.000 62.23827  ? 127 ALA C CA  1 
ATOM   5671 C C   . ALA C 1 167 ? -14.15943 -28.90249 27.69553  1.000 61.83827  ? 127 ALA C C   1 
ATOM   5672 O O   . ALA C 1 167 ? -14.13560 -30.12290 27.84932  1.000 61.09759  ? 127 ALA C O   1 
ATOM   5673 C CB  . ALA C 1 167 ? -11.87686 -28.76086 28.77324  1.000 58.09387  ? 127 ALA C CB  1 
ATOM   5674 N N   . GLY C 1 168 ? -15.11161 -28.28338 27.00776  1.000 57.94762  ? 128 GLY C N   1 
ATOM   5675 C CA  . GLY C 1 168 ? -16.19329 -28.99629 26.35442  1.000 58.94479  ? 128 GLY C CA  1 
ATOM   5676 C C   . GLY C 1 168 ? -16.30006 -28.59417 24.89632  1.000 64.87735  ? 128 GLY C C   1 
ATOM   5677 O O   . GLY C 1 168 ? -15.30107 -28.38697 24.20761  1.000 59.54648  ? 128 GLY C O   1 
ATOM   5678 N N   . LEU C 1 169 ? -17.54610 -28.47334 24.42893  1.000 64.83161  ? 129 LEU C N   1 
ATOM   5679 C CA  . LEU C 1 169 ? -17.79674 -28.04397 23.05693  1.000 56.92981  ? 129 LEU C CA  1 
ATOM   5680 C C   . LEU C 1 169 ? -17.79076 -26.52154 22.95274  1.000 62.69015  ? 129 LEU C C   1 
ATOM   5681 O O   . LEU C 1 169 ? -17.07072 -25.95332 22.12570  1.000 60.23163  ? 129 LEU C O   1 
ATOM   5682 C CB  . LEU C 1 169 ? -19.12157 -28.64660 22.56332  1.000 54.76777  ? 129 LEU C CB  1 
ATOM   5683 C CG  . LEU C 1 169 ? -19.94403 -28.16035 21.35967  1.000 57.95878  ? 129 LEU C CG  1 
ATOM   5684 C CD1 . LEU C 1 169 ? -20.85651 -26.99533 21.71617  1.000 57.32415  ? 129 LEU C CD1 1 
ATOM   5685 C CD2 . LEU C 1 169 ? -19.06385 -27.82816 20.15711  1.000 66.03673  ? 129 LEU C CD2 1 
ATOM   5686 N N   . LEU C 1 170 ? -18.58634 -25.84936 23.77929  1.000 57.82841  ? 130 LEU C N   1 
ATOM   5687 C CA  . LEU C 1 170 ? -18.61820 -24.39442 23.84558  1.000 55.63504  ? 130 LEU C CA  1 
ATOM   5688 C C   . LEU C 1 170 ? -19.04854 -23.96806 25.24427  1.000 64.80307  ? 130 LEU C C   1 
ATOM   5689 O O   . LEU C 1 170 ? -20.23491 -24.06819 25.57734  1.000 70.98351  ? 130 LEU C O   1 
ATOM   5690 C CB  . LEU C 1 170 ? -19.56254 -23.83368 22.78425  1.000 61.62501  ? 130 LEU C CB  1 
ATOM   5691 C CG  . LEU C 1 170 ? -19.76603 -22.31646 22.71592  1.000 59.40664  ? 130 LEU C CG  1 
ATOM   5692 C CD1 . LEU C 1 170 ? -18.42736 -21.61457 22.55767  1.000 56.20322  ? 130 LEU C CD1 1 
ATOM   5693 C CD2 . LEU C 1 170 ? -20.70938 -21.96091 21.56832  1.000 47.82264  ? 130 LEU C CD2 1 
ATOM   5694 N N   . PRO C 1 171 ? -18.12590 -23.49781 26.09932  1.000 63.31246  ? 131 PRO C N   1 
ATOM   5695 C CA  . PRO C 1 171 ? -16.69752 -23.24649 25.85831  1.000 59.03113  ? 131 PRO C CA  1 
ATOM   5696 C C   . PRO C 1 171 ? -15.87355 -24.51879 25.68568  1.000 62.16581  ? 131 PRO C C   1 
ATOM   5697 O O   . PRO C 1 171 ? -16.31209 -25.61057 26.02887  1.000 54.03965  ? 131 PRO C O   1 
ATOM   5698 C CB  . PRO C 1 171 ? -16.27862 -22.47234 27.11249  1.000 56.89088  ? 131 PRO C CB  1 
ATOM   5699 C CG  . PRO C 1 171 ? -17.15680 -23.03359 28.18445  1.000 54.45277  ? 131 PRO C CG  1 
ATOM   5700 C CD  . PRO C 1 171 ? -18.48451 -23.25155 27.50842  1.000 65.35803  ? 131 PRO C CD  1 
ATOM   5701 N N   . GLY C 1 172 ? -14.66234 -24.38304 25.15233  1.000 57.40659  ? 132 GLY C N   1 
ATOM   5702 C CA  . GLY C 1 172 ? -13.83079 -25.52721 24.84274  1.000 54.61160  ? 132 GLY C CA  1 
ATOM   5703 C C   . GLY C 1 172 ? -13.19379 -25.42550 23.47172  1.000 54.43745  ? 132 GLY C C   1 
ATOM   5704 O O   . GLY C 1 172 ? -12.49483 -24.45075 23.17698  1.000 57.08195  ? 132 GLY C O   1 
ATOM   5705 N N   . THR C 1 173 ? -13.42507 -26.42895 22.62164  1.000 55.02186  ? 133 THR C N   1 
ATOM   5706 C CA  . THR C 1 173 ? -12.77825 -26.44925 21.31328  1.000 56.08811  ? 133 THR C CA  1 
ATOM   5707 C C   . THR C 1 173 ? -13.26295 -25.31241 20.42230  1.000 50.40527  ? 133 THR C C   1 
ATOM   5708 O O   . THR C 1 173 ? -12.49523 -24.81263 19.59162  1.000 58.99214  ? 133 THR C O   1 
ATOM   5709 C CB  . THR C 1 173 ? -13.00532 -27.79813 20.63047  1.000 53.39598  ? 133 THR C CB  1 
ATOM   5710 O OG1 . THR C 1 173 ? -14.40055 -28.12371 20.65910  1.000 47.48878  ? 133 THR C OG1 1 
ATOM   5711 C CG2 . THR C 1 173 ? -12.20336 -28.89722 21.32438  1.000 45.70639  ? 133 THR C CG2 1 
ATOM   5712 N N   . CYS C 1 174 ? -14.52762 -24.90422 20.56303  1.000 50.23376  ? 134 CYS C N   1 
ATOM   5713 C CA  . CYS C 1 174 ? -15.00952 -23.74413 19.82009  1.000 53.86858  ? 134 CYS C CA  1 
ATOM   5714 C C   . CYS C 1 174 ? -14.27729 -22.47886 20.24560  1.000 54.97397  ? 134 CYS C C   1 
ATOM   5715 O O   . CYS C 1 174 ? -14.03671 -21.58677 19.42431  1.000 51.25623  ? 134 CYS C O   1 
ATOM   5716 C CB  . CYS C 1 174 ? -16.51759 -23.57852 20.00731  1.000 45.07057  ? 134 CYS C CB  1 
ATOM   5717 S SG  . CYS C 1 174 ? -17.52047 -24.77972 19.10681  1.000 57.18033  ? 134 CYS C SG  1 
ATOM   5718 N N   . SER C 1 175 ? -13.92790 -22.37568 21.52984  1.000 50.41276  ? 135 SER C N   1 
ATOM   5719 C CA  . SER C 1 175 ? -13.12845 -21.24309 21.98527  1.000 52.17862  ? 135 SER C CA  1 
ATOM   5720 C C   . SER C 1 175 ? -11.75553 -21.23451 21.32230  1.000 51.82657  ? 135 SER C C   1 
ATOM   5721 O O   . SER C 1 175 ? -11.23875 -20.17018 20.96122  1.000 51.70947  ? 135 SER C O   1 
ATOM   5722 C CB  . SER C 1 175 ? -12.99188 -21.27290 23.50789  1.000 49.96633  ? 135 SER C CB  1 
ATOM   5723 O OG  . SER C 1 175 ? -14.24368 -21.48275 24.13566  1.000 64.75844  ? 135 SER C OG  1 
ATOM   5724 N N   . MET C 1 176 ? -11.14421 -22.41232 21.16824  1.000 48.86843  ? 136 MET C N   1 
ATOM   5725 C CA  . MET C 1 176 ? -9.83045  -22.50060 20.53701  1.000 49.20502  ? 136 MET C CA  1 
ATOM   5726 C C   . MET C 1 176 ? -9.89010  -22.05972 19.07985  1.000 50.90211  ? 136 MET C C   1 
ATOM   5727 O O   . MET C 1 176 ? -9.04095  -21.28821 18.61656  1.000 46.28482  ? 136 MET C O   1 
ATOM   5728 C CB  . MET C 1 176 ? -9.29443  -23.92788 20.64979  1.000 49.23235  ? 136 MET C CB  1 
ATOM   5729 C CG  . MET C 1 176 ? -9.33895  -24.50005 22.05749  1.000 50.45727  ? 136 MET C CG  1 
ATOM   5730 S SD  . MET C 1 176 ? -8.82159  -26.23019 22.11915  1.000 58.01222  ? 136 MET C SD  1 
ATOM   5731 C CE  . MET C 1 176 ? -7.17009  -26.12955 21.43838  1.000 45.76381  ? 136 MET C CE  1 
ATOM   5732 N N   . ILE C 1 177 ? -10.87352 -22.56898 18.33365  1.000 45.40022  ? 137 ILE C N   1 
ATOM   5733 C CA  . ILE C 1 177 ? -11.06106 -22.14430 16.94941  1.000 52.87853  ? 137 ILE C CA  1 
ATOM   5734 C C   . ILE C 1 177 ? -11.29422 -20.63928 16.89228  1.000 53.84076  ? 137 ILE C C   1 
ATOM   5735 O O   . ILE C 1 177 ? -10.66597 -19.92423 16.10299  1.000 51.20206  ? 137 ILE C O   1 
ATOM   5736 C CB  . ILE C 1 177 ? -12.22228 -22.92007 16.30127  1.000 55.82933  ? 137 ILE C CB  1 
ATOM   5737 C CG1 . ILE C 1 177 ? -12.03795 -24.43658 16.46518  1.000 56.51273  ? 137 ILE C CG1 1 
ATOM   5738 C CG2 . ILE C 1 177 ? -12.35768 -22.53472 14.83330  1.000 51.17128  ? 137 ILE C CG2 1 
ATOM   5739 C CD1 . ILE C 1 177 ? -10.85052 -25.00875 15.74322  1.000 60.09519  ? 137 ILE C CD1 1 
ATOM   5740 N N   . ARG C 1 178 ? -12.20330 -20.14083 17.73762  1.000 53.67463  ? 138 ARG C N   1 
ATOM   5741 C CA  . ARG C 1 178 ? -12.47441 -18.70665 17.82042  1.000 46.85662  ? 138 ARG C CA  1 
ATOM   5742 C C   . ARG C 1 178 ? -11.20083 -17.90253 18.06242  1.000 52.16763  ? 138 ARG C C   1 
ATOM   5743 O O   . ARG C 1 178 ? -10.99880 -16.84319 17.45705  1.000 47.88348  ? 138 ARG C O   1 
ATOM   5744 C CB  . ARG C 1 178 ? -13.49578 -18.44324 18.92924  1.000 41.23515  ? 138 ARG C CB  1 
ATOM   5745 C CG  . ARG C 1 178 ? -14.22238 -17.11337 18.84410  1.000 62.24222  ? 138 ARG C CG  1 
ATOM   5746 C CD  . ARG C 1 178 ? -15.61412 -17.24526 19.44134  1.000 68.46430  ? 138 ARG C CD  1 
ATOM   5747 N NE  . ARG C 1 178 ? -15.57087 -17.70685 20.82375  1.000 56.64238  ? 138 ARG C NE  1 
ATOM   5748 C CZ  . ARG C 1 178 ? -16.64263 -17.98489 21.55321  1.000 60.09836  ? 138 ARG C CZ  1 
ATOM   5749 N NH1 . ARG C 1 178 ? -17.86287 -17.89257 21.05089  1.000 54.85686  ? 138 ARG C NH1 1 
ATOM   5750 N NH2 . ARG C 1 178 ? -16.48590 -18.37192 22.81626  1.000 63.77424  ? 138 ARG C NH2 1 
ATOM   5751 N N   . SER C 1 179 ? -10.33578 -18.38248 18.95913  1.000 52.38554  ? 139 SER C N   1 
ATOM   5752 C CA  . SER C 1 179 ? -9.11683  -17.64517 19.27534  1.000 48.43095  ? 139 SER C CA  1 
ATOM   5753 C C   . SER C 1 179 ? -8.12430  -17.66600 18.11965  1.000 50.39004  ? 139 SER C C   1 
ATOM   5754 O O   . SER C 1 179 ? -7.40012  -16.68478 17.91279  1.000 46.05244  ? 139 SER C O   1 
ATOM   5755 C CB  . SER C 1 179 ? -8.46235  -18.21670 20.53177  1.000 47.56077  ? 139 SER C CB  1 
ATOM   5756 O OG  . SER C 1 179 ? -9.36308  -18.23067 21.62311  1.000 51.42308  ? 139 SER C OG  1 
ATOM   5757 N N   . ILE C 1 180 ? -8.06037  -18.77183 17.37211  1.000 46.78332  ? 140 ILE C N   1 
ATOM   5758 C CA  . ILE C 1 180 ? -7.15740  -18.83969 16.22732  1.000 42.02085  ? 140 ILE C CA  1 
ATOM   5759 C C   . ILE C 1 180 ? -7.60270  -17.87167 15.13976  1.000 47.66021  ? 140 ILE C C   1 
ATOM   5760 O O   . ILE C 1 180 ? -6.77916  -17.17055 14.54010  1.000 45.39659  ? 140 ILE C O   1 
ATOM   5761 C CB  . ILE C 1 180 ? -7.06259  -20.28424 15.70653  1.000 54.29780  ? 140 ILE C CB  1 
ATOM   5762 C CG1 . ILE C 1 180 ? -6.37835  -21.17670 16.74211  1.000 41.53980  ? 140 ILE C CG1 1 
ATOM   5763 C CG2 . ILE C 1 180 ? -6.31074  -20.32723 14.38232  1.000 48.80297  ? 140 ILE C CG2 1 
ATOM   5764 C CD1 . ILE C 1 180 ? -6.44964  -22.64873 16.41248  1.000 45.26170  ? 140 ILE C CD1 1 
ATOM   5765 N N   . LEU C 1 181 ? -8.91161  -17.80361 14.88130  1.000 51.12714  ? 141 LEU C N   1 
ATOM   5766 C CA  . LEU C 1 181 ? -9.43535  -16.80514 13.95462  1.000 50.14686  ? 141 LEU C CA  1 
ATOM   5767 C C   . LEU C 1 181 ? -9.05713  -15.39762 14.39757  1.000 51.27977  ? 141 LEU C C   1 
ATOM   5768 O O   . LEU C 1 181 ? -8.79298  -14.52464 13.56214  1.000 51.57005  ? 141 LEU C O   1 
ATOM   5769 C CB  . LEU C 1 181 ? -10.95664 -16.93392 13.83725  1.000 46.19221  ? 141 LEU C CB  1 
ATOM   5770 C CG  . LEU C 1 181 ? -11.56098 -18.28566 13.44747  1.000 51.72483  ? 141 LEU C CG  1 
ATOM   5771 C CD1 . LEU C 1 181 ? -13.07337 -18.17102 13.30131  1.000 48.59541  ? 141 LEU C CD1 1 
ATOM   5772 C CD2 . LEU C 1 181 ? -10.93323 -18.82050 12.16980  1.000 49.48226  ? 141 LEU C CD2 1 
ATOM   5773 N N   . GLU C 1 182 ? -9.04229  -15.15745 15.71128  1.000 47.23829  ? 142 GLU C N   1 
ATOM   5774 C CA  . GLU C 1 182 ? -8.79970  -13.81396 16.22862  1.000 54.74193  ? 142 GLU C CA  1 
ATOM   5775 C C   . GLU C 1 182 ? -7.42427  -13.28992 15.82045  1.000 62.45024  ? 142 GLU C C   1 
ATOM   5776 O O   . GLU C 1 182 ? -7.29512  -12.14138 15.38522  1.000 55.01964  ? 142 GLU C O   1 
ATOM   5777 C CB  . GLU C 1 182 ? -8.95904  -13.80715 17.74894  1.000 50.02369  ? 142 GLU C CB  1 
ATOM   5778 C CG  . GLU C 1 182 ? -8.95044  -12.42123 18.37049  1.000 56.95528  ? 142 GLU C CG  1 
ATOM   5779 C CD  . GLU C 1 182 ? -10.33112 -11.78950 18.40565  1.000 58.78545  ? 142 GLU C CD  1 
ATOM   5780 O OE1 . GLU C 1 182 ? -11.31298 -12.48081 18.05718  1.000 73.07831  ? 142 GLU C OE1 1 
ATOM   5781 O OE2 . GLU C 1 182 ? -10.43490 -10.60349 18.78597  1.000 72.74069  ? 142 GLU C OE2 1 
ATOM   5782 N N   . PHE C 1 183 ? -6.37728  -14.10753 15.95882  1.000 49.25474  ? 143 PHE C N   1 
ATOM   5783 C CA  . PHE C 1 183 ? -5.04226  -13.61671 15.63304  1.000 50.29603  ? 143 PHE C CA  1 
ATOM   5784 C C   . PHE C 1 183 ? -4.71156  -13.75638 14.15377  1.000 52.81871  ? 143 PHE C C   1 
ATOM   5785 O O   . PHE C 1 183 ? -3.74097  -13.14927 13.68907  1.000 52.87270  ? 143 PHE C O   1 
ATOM   5786 C CB  . PHE C 1 183 ? -3.96400  -14.29519 16.50588  1.000 51.54543  ? 143 PHE C CB  1 
ATOM   5787 C CG  . PHE C 1 183 ? -3.63803  -15.73022 16.14229  1.000 48.24773  ? 143 PHE C CG  1 
ATOM   5788 C CD1 . PHE C 1 183 ? -2.83248  -16.02850 15.05037  1.000 45.98601  ? 143 PHE C CD1 1 
ATOM   5789 C CD2 . PHE C 1 183 ? -4.07397  -16.77452 16.94400  1.000 43.45780  ? 143 PHE C CD2 1 
ATOM   5790 C CE1 . PHE C 1 183 ? -2.51062  -17.33982 14.73337  1.000 48.02025  ? 143 PHE C CE1 1 
ATOM   5791 C CE2 . PHE C 1 183 ? -3.75075  -18.08978 16.63437  1.000 52.83850  ? 143 PHE C CE2 1 
ATOM   5792 C CZ  . PHE C 1 183 ? -2.96954  -18.36965 15.52505  1.000 45.70673  ? 143 PHE C CZ  1 
ATOM   5793 N N   . MET C 1 184 ? -5.48571  -14.54538 13.40854  1.000 52.86394  ? 144 MET C N   1 
ATOM   5794 C CA  . MET C 1 184 ? -5.34842  -14.55582 11.95729  1.000 46.80026  ? 144 MET C CA  1 
ATOM   5795 C C   . MET C 1 184 ? -5.86806  -13.26023 11.34492  1.000 54.02159  ? 144 MET C C   1 
ATOM   5796 O O   . MET C 1 184 ? -5.38562  -12.83464 10.28948  1.000 46.13481  ? 144 MET C O   1 
ATOM   5797 C CB  . MET C 1 184 ? -6.11273  -15.74747 11.38146  1.000 47.51496  ? 144 MET C CB  1 
ATOM   5798 C CG  . MET C 1 184 ? -5.52208  -17.10313 11.72446  1.000 45.10571  ? 144 MET C CG  1 
ATOM   5799 S SD  . MET C 1 184 ? -6.42861  -18.48040 10.98333  1.000 55.13486  ? 144 MET C SD  1 
ATOM   5800 C CE  . MET C 1 184 ? -5.97249  -18.32810 9.26859   1.000 42.87595  ? 144 MET C CE  1 
ATOM   5801 N N   . ALA C 1 185 ? -6.84710  -12.62642 11.98944  1.000 54.54548  ? 145 ALA C N   1 
ATOM   5802 C CA  . ALA C 1 185 ? -7.42966  -11.37828 11.49660  1.000 58.04974  ? 145 ALA C CA  1 
ATOM   5803 C C   . ALA C 1 185 ? -7.83438  -10.53341 12.69309  1.000 52.48834  ? 145 ALA C C   1 
ATOM   5804 O O   . ALA C 1 185 ? -8.98007  -10.59596 13.15894  1.000 50.54901  ? 145 ALA C O   1 
ATOM   5805 C CB  . ALA C 1 185 ? -8.62578  -11.63334 10.58102  1.000 47.40508  ? 145 ALA C CB  1 
ATOM   5806 N N   . PRO C 1 186 ? -6.90995  -9.73055  13.22911  1.000 59.17984  ? 146 PRO C N   1 
ATOM   5807 C CA  . PRO C 1 186 ? -7.19165  -9.03229  14.49705  1.000 49.65079  ? 146 PRO C CA  1 
ATOM   5808 C C   . PRO C 1 186 ? -8.34683  -8.04865  14.43126  1.000 51.30731  ? 146 PRO C C   1 
ATOM   5809 O O   . PRO C 1 186 ? -9.06091  -7.88696  15.42896  1.000 55.44166  ? 146 PRO C O   1 
ATOM   5810 C CB  . PRO C 1 186 ? -5.86697  -8.31862  14.80005  1.000 48.30253  ? 146 PRO C CB  1 
ATOM   5811 C CG  . PRO C 1 186 ? -4.83404  -9.11423  14.07423  1.000 41.53232  ? 146 PRO C CG  1 
ATOM   5812 C CD  . PRO C 1 186 ? -5.50033  -9.59638  12.82171  1.000 46.69099  ? 146 PRO C CD  1 
ATOM   5813 N N   . TYR C 1 187 ? -8.55927  -7.38806  13.29906  1.000 51.81883  ? 147 TYR C N   1 
ATOM   5814 C CA  . TYR C 1 187 ? -9.65741  -6.44395  13.14629  1.000 52.92097  ? 147 TYR C CA  1 
ATOM   5815 C C   . TYR C 1 187 ? -10.82895 -7.15060  12.48276  1.000 58.92562  ? 147 TYR C C   1 
ATOM   5816 O O   . TYR C 1 187 ? -10.64769 -7.83640  11.47415  1.000 59.94821  ? 147 TYR C O   1 
ATOM   5817 C CB  . TYR C 1 187 ? -9.23837  -5.23666  12.30675  1.000 50.04044  ? 147 TYR C CB  1 
ATOM   5818 C CG  . TYR C 1 187 ? -8.05152  -4.47721  12.85053  1.000 57.46380  ? 147 TYR C CG  1 
ATOM   5819 C CD1 . TYR C 1 187 ? -7.97824  -4.13262  14.19312  1.000 65.47810  ? 147 TYR C CD1 1 
ATOM   5820 C CD2 . TYR C 1 187 ? -7.00643  -4.09784  12.01788  1.000 60.08040  ? 147 TYR C CD2 1 
ATOM   5821 C CE1 . TYR C 1 187 ? -6.89551  -3.43480  14.69299  1.000 64.19995  ? 147 TYR C CE1 1 
ATOM   5822 C CE2 . TYR C 1 187 ? -5.91924  -3.40140  12.50789  1.000 64.05707  ? 147 TYR C CE2 1 
ATOM   5823 C CZ  . TYR C 1 187 ? -5.86953  -3.07175  13.84582  1.000 65.39078  ? 147 TYR C CZ  1 
ATOM   5824 O OH  . TYR C 1 187 ? -4.79002  -2.37660  14.34055  1.000 71.52868  ? 147 TYR C OH  1 
ATOM   5825 N N   . GLY C 1 188 ? -12.01949 -6.98047  13.04133  1.000 51.89120  ? 148 GLY C N   1 
ATOM   5826 C CA  . GLY C 1 188 ? -13.21599 -7.58305  12.50020  1.000 46.03577  ? 148 GLY C CA  1 
ATOM   5827 C C   . GLY C 1 188 ? -14.10132 -8.12633  13.59926  1.000 49.54721  ? 148 GLY C C   1 
ATOM   5828 O O   . GLY C 1 188 ? -13.93073 -7.81593  14.77754  1.000 48.65909  ? 148 GLY C O   1 
ATOM   5829 N N   . ILE C 1 189 ? -15.06811 -8.94973  13.19543  1.000 43.09078  ? 149 ILE C N   1 
ATOM   5830 C CA  . ILE C 1 189 ? -16.09520 -9.46892  14.08997  1.000 46.65082  ? 149 ILE C CA  1 
ATOM   5831 C C   . ILE C 1 189 ? -16.24227 -10.96544 13.85143  1.000 54.89661  ? 149 ILE C C   1 
ATOM   5832 O O   . ILE C 1 189 ? -16.19902 -11.43065 12.70664  1.000 49.68080  ? 149 ILE C O   1 
ATOM   5833 C CB  . ILE C 1 189 ? -17.44827 -8.74999  13.88309  1.000 54.58842  ? 149 ILE C CB  1 
ATOM   5834 C CG1 . ILE C 1 189 ? -17.32327 -7.25840  14.19527  1.000 52.26427  ? 149 ILE C CG1 1 
ATOM   5835 C CG2 . ILE C 1 189 ? -18.53424 -9.36606  14.75335  1.000 52.74790  ? 149 ILE C CG2 1 
ATOM   5836 C CD1 . ILE C 1 189 ? -18.61219 -6.48866  14.01882  1.000 51.84605  ? 149 ILE C CD1 1 
ATOM   5837 N N   . THR C 1 190 ? -16.40919 -11.71942 14.93326  1.000 47.87675  ? 150 THR C N   1 
ATOM   5838 C CA  . THR C 1 190 ? -16.71806 -13.13929 14.86146  1.000 51.59047  ? 150 THR C CA  1 
ATOM   5839 C C   . THR C 1 190 ? -18.13285 -13.36515 15.36944  1.000 51.33977  ? 150 THR C C   1 
ATOM   5840 O O   . THR C 1 190 ? -18.50002 -12.86954 16.44021  1.000 58.44907  ? 150 THR C O   1 
ATOM   5841 C CB  . THR C 1 190 ? -15.73277 -13.97163 15.68677  1.000 43.11234  ? 150 THR C CB  1 
ATOM   5842 O OG1 . THR C 1 190 ? -14.41477 -13.85028 15.13852  1.000 48.38645  ? 150 THR C OG1 1 
ATOM   5843 C CG2 . THR C 1 190 ? -16.14713 -15.43807 15.69198  1.000 35.20726  ? 150 THR C CG2 1 
ATOM   5844 N N   . TYR C 1 191 ? -18.91815 -14.11307 14.60509  1.000 46.85120  ? 151 TYR C N   1 
ATOM   5845 C CA  . TYR C 1 191 ? -20.25864 -14.50528 15.00650  1.000 54.03291  ? 151 TYR C CA  1 
ATOM   5846 C C   . TYR C 1 191 ? -20.24782 -15.99356 15.31012  1.000 54.79330  ? 151 TYR C C   1 
ATOM   5847 O O   . TYR C 1 191 ? -19.82947 -16.79612 14.46959  1.000 53.67460  ? 151 TYR C O   1 
ATOM   5848 C CB  . TYR C 1 191 ? -21.27668 -14.19777 13.90820  1.000 46.41374  ? 151 TYR C CB  1 
ATOM   5849 C CG  . TYR C 1 191 ? -21.43878 -12.72681 13.60807  1.000 53.32966  ? 151 TYR C CG  1 
ATOM   5850 C CD1 . TYR C 1 191 ? -21.70114 -11.81492 14.62162  1.000 53.91058  ? 151 TYR C CD1 1 
ATOM   5851 C CD2 . TYR C 1 191 ? -21.32203 -12.24706 12.30976  1.000 56.19087  ? 151 TYR C CD2 1 
ATOM   5852 C CE1 . TYR C 1 191 ? -21.85313 -10.46718 14.35005  1.000 64.66088  ? 151 TYR C CE1 1 
ATOM   5853 C CE2 . TYR C 1 191 ? -21.46937 -10.89968 12.02890  1.000 51.43458  ? 151 TYR C CE2 1 
ATOM   5854 C CZ  . TYR C 1 191 ? -21.73453 -10.01536 13.05376  1.000 66.21045  ? 151 TYR C CZ  1 
ATOM   5855 O OH  . TYR C 1 191 ? -21.88191 -8.67471  12.77990  1.000 68.09190  ? 151 TYR C OH  1 
ATOM   5856 N N   . THR C 1 192 ? -20.71110 -16.36022 16.49970  1.000 41.55216  ? 152 THR C N   1 
ATOM   5857 C CA  . THR C 1 192 ? -20.84629 -17.75939 16.88605  1.000 52.30071  ? 152 THR C CA  1 
ATOM   5858 C C   . THR C 1 192 ? -22.33654 -18.07158 16.91440  1.000 54.85444  ? 152 THR C C   1 
ATOM   5859 O O   . THR C 1 192 ? -23.06975 -17.56171 17.76905  1.000 58.03288  ? 152 THR C O   1 
ATOM   5860 C CB  . THR C 1 192 ? -20.18934 -18.03381 18.23900  1.000 56.17806  ? 152 THR C CB  1 
ATOM   5861 O OG1 . THR C 1 192 ? -18.80873 -17.65171 18.19071  1.000 57.53024  ? 152 THR C OG1 1 
ATOM   5862 C CG2 . THR C 1 192 ? -20.27701 -19.51285 18.58509  1.000 47.53141  ? 152 THR C CG2 1 
ATOM   5863 N N   . ASN C 1 193 ? -22.77840 -18.91096 15.98378  1.000 55.60796  ? 153 ASN C N   1 
ATOM   5864 C CA  . ASN C 1 193 ? -24.19247 -19.20387 15.78290  1.000 42.72466  ? 153 ASN C CA  1 
ATOM   5865 C C   . ASN C 1 193 ? -24.44540 -20.64539 16.19875  1.000 56.18882  ? 153 ASN C C   1 
ATOM   5866 O O   . ASN C 1 193 ? -24.01519 -21.57952 15.51348  1.000 67.24492  ? 153 ASN C O   1 
ATOM   5867 C CB  . ASN C 1 193 ? -24.59167 -18.96984 14.32934  1.000 42.98660  ? 153 ASN C CB  1 
ATOM   5868 C CG  . ASN C 1 193 ? -24.21745 -17.58417 13.84160  1.000 56.08466  ? 153 ASN C CG  1 
ATOM   5869 O OD1 . ASN C 1 193 ? -24.83444 -16.59124 14.22425  1.000 51.78008  ? 153 ASN C OD1 1 
ATOM   5870 N ND2 . ASN C 1 193 ? -23.19106 -17.50989 13.00052  1.000 52.72662  ? 153 ASN C ND2 1 
ATOM   5871 N N   . VAL C 1 194 ? -25.14929 -20.82047 17.31436  1.000 51.47594  ? 154 VAL C N   1 
ATOM   5872 C CA  . VAL C 1 194 ? -25.40912 -22.13679 17.88568  1.000 62.55450  ? 154 VAL C CA  1 
ATOM   5873 C C   . VAL C 1 194 ? -26.66541 -22.67344 17.20897  1.000 69.42854  ? 154 VAL C C   1 
ATOM   5874 O O   . VAL C 1 194 ? -27.78123 -22.25734 17.52401  1.000 56.05794  ? 154 VAL C O   1 
ATOM   5875 C CB  . VAL C 1 194 ? -25.57126 -22.07644 19.40533  1.000 56.59430  ? 154 VAL C CB  1 
ATOM   5876 C CG1 . VAL C 1 194 ? -25.80584 -23.46975 19.96913  1.000 57.99482  ? 154 VAL C CG1 1 
ATOM   5877 C CG2 . VAL C 1 194 ? -24.35444 -21.43580 20.04701  1.000 59.99145  ? 154 VAL C CG2 1 
ATOM   5878 N N   . GLY C 1 195 ? -26.47699 -23.59410 16.26348  1.000 80.90190  ? 155 GLY C N   1 
ATOM   5879 C CA  . GLY C 1 195 ? -27.55514 -24.11164 15.45361  1.000 55.44609  ? 155 GLY C CA  1 
ATOM   5880 C C   . GLY C 1 195 ? -28.63569 -24.75832 16.29376  1.000 55.66773  ? 155 GLY C C   1 
ATOM   5881 O O   . GLY C 1 195 ? -28.48010 -24.94265 17.50590  1.000 70.96185  ? 155 GLY C O   1 
ATOM   5882 N N   . PRO C 1 196 ? -29.76427 -25.11317 15.66088  1.000 68.50207  ? 156 PRO C N   1 
ATOM   5883 C CA  . PRO C 1 196 ? -30.90274 -25.65728 16.41719  1.000 54.65418  ? 156 PRO C CA  1 
ATOM   5884 C C   . PRO C 1 196 ? -30.54236 -26.84524 17.29404  1.000 54.57544  ? 156 PRO C C   1 
ATOM   5885 O O   . PRO C 1 196 ? -30.08347 -27.88102 16.80547  1.000 64.42382  ? 156 PRO C O   1 
ATOM   5886 C CB  . PRO C 1 196 ? -31.89170 -26.06084 15.31590  1.000 51.27127  ? 156 PRO C CB  1 
ATOM   5887 C CG  . PRO C 1 196 ? -31.54771 -25.18049 14.16841  1.000 47.36817  ? 156 PRO C CG  1 
ATOM   5888 C CD  . PRO C 1 196 ? -30.06013 -24.99763 14.22326  1.000 63.33840  ? 156 PRO C CD  1 
ATOM   5889 N N   . GLY C 1 197 ? -30.73935 -26.69018 18.59603  1.000 51.38496  ? 157 GLY C N   1 
ATOM   5890 C CA  . GLY C 1 197 ? -30.44887 -27.74715 19.54293  1.000 54.68102  ? 157 GLY C CA  1 
ATOM   5891 C C   . GLY C 1 197 ? -31.01596 -27.39001 20.89527  1.000 61.16701  ? 157 GLY C C   1 
ATOM   5892 O O   . GLY C 1 197 ? -31.32654 -26.22602 21.17160  1.000 60.04668  ? 157 GLY C O   1 
ATOM   5893 N N   . MET C 1 198 ? -31.14244 -28.40735 21.74146  1.000 57.84716  ? 158 MET C N   1 
ATOM   5894 C CA  . MET C 1 198 ? -31.72444 -28.18654 23.05543  1.000 72.26833  ? 158 MET C CA  1 
ATOM   5895 C C   . MET C 1 198 ? -30.69483 -27.58996 24.00905  1.000 72.11822  ? 158 MET C C   1 
ATOM   5896 O O   . MET C 1 198 ? -29.50379 -27.91317 23.96516  1.000 73.41362  ? 158 MET C O   1 
ATOM   5897 C CB  . MET C 1 198 ? -32.31317 -29.48254 23.62780  1.000 67.66318  ? 158 MET C CB  1 
ATOM   5898 C CG  . MET C 1 198 ? -31.32321 -30.41289 24.29692  1.000 85.53564  ? 158 MET C CG  1 
ATOM   5899 S SD  . MET C 1 198 ? -32.10623 -31.91492 24.92349  1.000 80.18620  ? 158 MET C SD  1 
ATOM   5900 C CE  . MET C 1 198 ? -33.01160 -31.26519 26.32854  1.000 73.37203  ? 158 MET C CE  1 
ATOM   5901 N N   . SER C 1 199 ? -31.17199 -26.69817 24.86873  1.000 74.66789  ? 159 SER C N   1 
ATOM   5902 C CA  . SER C 1 199 ? -30.38436 -26.14410 25.95501  1.000 85.89933  ? 159 SER C CA  1 
ATOM   5903 C C   . SER C 1 199 ? -30.96554 -26.61270 27.28024  1.000 90.11776  ? 159 SER C C   1 
ATOM   5904 O O   . SER C 1 199 ? -32.16020 -26.91454 27.38195  1.000 96.22356  ? 159 SER C O   1 
ATOM   5905 C CB  . SER C 1 199 ? -30.35676 -24.61012 25.89544  1.000 76.14003  ? 159 SER C CB  1 
ATOM   5906 O OG  . SER C 1 199 ? -31.43689 -24.12472 25.11749  1.000 73.77363  ? 159 SER C OG  1 
ATOM   5907 N N   . MET C 1 200 ? -30.10898 -26.69374 28.30046  1.000 99.65291  ? 160 MET C N   1 
ATOM   5908 C CA  . MET C 1 200 ? -30.56390 -27.18887 29.59344  1.000 99.52126  ? 160 MET C CA  1 
ATOM   5909 C C   . MET C 1 200 ? -31.34200 -26.13373 30.37683  1.000 99.51646  ? 160 MET C C   1 
ATOM   5910 O O   . MET C 1 200 ? -31.52235 -26.23993 31.59938  1.000 92.79314  ? 160 MET C O   1 
ATOM   5911 C CB  . MET C 1 200 ? -29.39932 -27.74732 30.40442  1.000 101.49326 ? 160 MET C CB  1 
ATOM   5912 C CG  . MET C 1 200 ? -29.81921 -29.04934 31.07439  1.000 108.35812 ? 160 MET C CG  1 
ATOM   5913 S SD  . MET C 1 200 ? -30.83253 -29.93425 29.85691  1.000 124.74218 ? 160 MET C SD  1 
ATOM   5914 C CE  . MET C 1 200 ? -30.51747 -31.65642 30.22930  1.000 79.25817  ? 160 MET C CE  1 
ATOM   5915 N N   . SER C 1 201 ? -31.80869 -25.12739 29.64223  1.000 96.92562  ? 161 SER C N   1 
ATOM   5916 C CA  . SER C 1 201 ? -32.80035 -24.16483 30.08251  1.000 85.55420  ? 161 SER C CA  1 
ATOM   5917 C C   . SER C 1 201 ? -34.18170 -24.79208 30.09217  1.000 96.88673  ? 161 SER C C   1 
ATOM   5918 O O   . SER C 1 201 ? -35.14769 -24.14058 30.49525  1.000 88.42938  ? 161 SER C O   1 
ATOM   5919 C CB  . SER C 1 201 ? -32.79415 -22.93500 29.17349  1.000 93.79129  ? 161 SER C CB  1 
ATOM   5920 O OG  . SER C 1 201 ? -31.48522 -22.60974 28.74262  1.000 123.25277 ? 161 SER C OG  1 
ATOM   5921 N N   . ALA C 1 202 ? -34.29007 -26.02592 29.59531  1.000 92.60746  ? 162 ALA C N   1 
ATOM   5922 C CA  . ALA C 1 202 ? -35.54067 -26.76374 29.67667  1.000 92.95536  ? 162 ALA C CA  1 
ATOM   5923 C C   . ALA C 1 202 ? -35.78185 -27.24769 31.09815  1.000 95.80233  ? 162 ALA C C   1 
ATOM   5924 O O   . ALA C 1 202 ? -36.92906 -27.51037 31.48022  1.000 109.66452 ? 162 ALA C O   1 
ATOM   5925 C CB  . ALA C 1 202 ? -35.52123 -27.93920 28.69963  1.000 68.94309  ? 162 ALA C CB  1 
ATOM   5926 N N   . SER C 1 203 ? -34.71250 -27.39803 31.88276  1.000 91.92075  ? 163 SER C N   1 
ATOM   5927 C CA  . SER C 1 203 ? -34.88199 -27.72169 33.29270  1.000 102.29764 ? 163 SER C CA  1 
ATOM   5928 C C   . SER C 1 203 ? -35.55449 -26.56866 34.02795  1.000 108.22936 ? 163 SER C C   1 
ATOM   5929 O O   . SER C 1 203 ? -36.41417 -26.78987 34.89035  1.000 114.57174 ? 163 SER C O   1 
ATOM   5930 C CB  . SER C 1 203 ? -33.52981 -28.04804 33.92671  1.000 92.42378  ? 163 SER C CB  1 
ATOM   5931 O OG  . SER C 1 203 ? -32.98083 -29.23833 33.39149  1.000 94.70869  ? 163 SER C OG  1 
ATOM   5932 N N   . VAL C 1 204 ? -35.17795 -25.33004 33.69524  1.000 97.30717  ? 164 VAL C N   1 
ATOM   5933 C CA  . VAL C 1 204 ? -35.76739 -24.16704 34.34926  1.000 104.11815 ? 164 VAL C CA  1 
ATOM   5934 C C   . VAL C 1 204 ? -37.17685 -23.90175 33.83075  1.000 108.66753 ? 164 VAL C C   1 
ATOM   5935 O O   . VAL C 1 204 ? -37.96095 -23.21530 34.49937  1.000 108.24821 ? 164 VAL C O   1 
ATOM   5936 C CB  . VAL C 1 204 ? -34.89814 -22.91162 34.14531  1.000 111.67136 ? 164 VAL C CB  1 
ATOM   5937 C CG1 . VAL C 1 204 ? -33.40634 -23.23791 34.33911  1.000 112.01202 ? 164 VAL C CG1 1 
ATOM   5938 C CG2 . VAL C 1 204 ? -35.20426 -22.19825 32.83035  1.000 105.67214 ? 164 VAL C CG2 1 
ATOM   5939 N N   . ALA C 1 205 ? -37.51183 -24.42419 32.64555  1.000 102.37191 ? 165 ALA C N   1 
ATOM   5940 C CA  . ALA C 1 205 ? -38.85224 -24.26418 32.09191  1.000 102.15017 ? 165 ALA C CA  1 
ATOM   5941 C C   . ALA C 1 205 ? -39.88570 -25.04945 32.88600  1.000 109.98611 ? 165 ALA C C   1 
ATOM   5942 O O   . ALA C 1 205 ? -41.04617 -24.62733 32.97399  1.000 99.94891  ? 165 ALA C O   1 
ATOM   5943 C CB  . ALA C 1 205 ? -38.87016 -24.68783 30.62359  1.000 97.84780  ? 165 ALA C CB  1 
ATOM   5944 N N   . VAL C 1 206 ? -39.48725 -26.18156 33.46812  1.000 105.34477 ? 166 VAL C N   1 
ATOM   5945 C CA  . VAL C 1 206 ? -40.37672 -26.97256 34.30876  1.000 114.90811 ? 166 VAL C CA  1 
ATOM   5946 C C   . VAL C 1 206 ? -40.69283 -26.14909 35.54910  1.000 120.52566 ? 166 VAL C C   1 
ATOM   5947 O O   . VAL C 1 206 ? -39.88575 -26.07924 36.48296  1.000 113.57544 ? 166 VAL C O   1 
ATOM   5948 C CB  . VAL C 1 206 ? -39.73070 -28.32148 34.67601  1.000 116.33333 ? 166 VAL C CB  1 
ATOM   5949 C CG1 . VAL C 1 206 ? -40.72309 -29.21878 35.39423  1.000 118.76916 ? 166 VAL C CG1 1 
ATOM   5950 C CG2 . VAL C 1 206 ? -39.17537 -29.01095 33.43187  1.000 102.32354 ? 166 VAL C CG2 1 
ATOM   5951 N N   . LYS C 1 207 ? -41.86620 -25.50934 35.56272  1.000 127.21742 ? 167 LYS C N   1 
ATOM   5952 C CA  . LYS C 1 207 ? -42.20182 -24.60952 36.66037  1.000 124.12766 ? 167 LYS C CA  1 
ATOM   5953 C C   . LYS C 1 207 ? -43.53959 -24.91119 37.32172  1.000 136.00355 ? 167 LYS C C   1 
ATOM   5954 O O   . LYS C 1 207 ? -43.58255 -25.29144 38.49640  1.000 142.52407 ? 167 LYS C O   1 
ATOM   5955 C CB  . LYS C 1 207 ? -42.23705 -23.17557 36.13373  1.000 101.80579 ? 167 LYS C CB  1 
ATOM   5956 C CG  . LYS C 1 207 ? -40.88268 -22.52476 35.98798  1.000 112.52154 ? 167 LYS C CG  1 
ATOM   5957 C CD  . LYS C 1 207 ? -40.95652 -21.33026 35.05007  1.000 110.19948 ? 167 LYS C CD  1 
ATOM   5958 C CE  . LYS C 1 207 ? -42.15156 -20.44804 35.36608  1.000 115.72828 ? 167 LYS C CE  1 
ATOM   5959 N NZ  . LYS C 1 207 ? -42.13028 -19.17916 34.58904  1.000 114.46683 ? 167 LYS C NZ  1 
ATOM   5960 N N   . ALA C 1 208 ? -44.63123 -24.80918 36.56955  1.000 131.97335 ? 168 ALA C N   1 
ATOM   5961 C CA  . ALA C 1 208 ? -45.93464 -25.05625 37.16235  1.000 126.90229 ? 168 ALA C CA  1 
ATOM   5962 C C   . ALA C 1 208 ? -46.09103 -26.55297 37.38545  1.000 140.38677 ? 168 ALA C C   1 
ATOM   5963 O O   . ALA C 1 208 ? -45.52026 -27.36770 36.65479  1.000 141.31683 ? 168 ALA C O   1 
ATOM   5964 C CB  . ALA C 1 208 ? -47.04843 -24.51897 36.26751  1.000 97.41859  ? 168 ALA C CB  1 
ATOM   5965 N N   . ILE C 1 209 ? -46.90294 -26.91595 38.37690  1.000 145.80633 ? 169 ILE C N   1 
ATOM   5966 C CA  . ILE C 1 209 ? -46.95555 -28.30629 38.82642  1.000 143.36692 ? 169 ILE C CA  1 
ATOM   5967 C C   . ILE C 1 209 ? -47.71336 -29.10967 37.77836  1.000 144.92018 ? 169 ILE C C   1 
ATOM   5968 O O   . ILE C 1 209 ? -48.93813 -29.00226 37.67124  1.000 156.08799 ? 169 ILE C O   1 
ATOM   5969 C CB  . ILE C 1 209 ? -47.60843 -28.43149 40.21245  1.000 142.75461 ? 169 ILE C CB  1 
ATOM   5970 C CG1 . ILE C 1 209 ? -46.82841 -27.63496 41.26551  1.000 139.79156 ? 169 ILE C CG1 1 
ATOM   5971 C CG2 . ILE C 1 209 ? -47.68694 -29.90268 40.62678  1.000 130.32949 ? 169 ILE C CG2 1 
ATOM   5972 C CD1 . ILE C 1 209 ? -45.67156 -28.36255 41.92857  1.000 120.19201 ? 169 ILE C CD1 1 
ATOM   5973 N N   . GLU C 1 210 ? -46.96912 -29.90109 36.99787  1.000 141.89015 ? 170 GLU C N   1 
ATOM   5974 C CA  . GLU C 1 210 ? -47.46451 -30.72601 35.90346  1.000 136.56894 ? 170 GLU C CA  1 
ATOM   5975 C C   . GLU C 1 210 ? -48.02779 -29.87773 34.76637  1.000 135.89001 ? 170 GLU C C   1 
ATOM   5976 O O   . GLU C 1 210 ? -48.07834 -30.33375 33.61651  1.000 126.85530 ? 170 GLU C O   1 
ATOM   5977 C CB  . GLU C 1 210 ? -48.49920 -31.73667 36.39617  1.000 120.70214 ? 170 GLU C CB  1 
ATOM   5978 C CG  . GLU C 1 210 ? -48.86165 -32.78278 35.34485  1.000 125.67065 ? 170 GLU C CG  1 
ATOM   5979 C CD  . GLU C 1 210 ? -49.57548 -33.98594 35.96818  1.000 138.06946 ? 170 GLU C CD  1 
ATOM   5980 O OE1 . GLU C 1 210 ? -49.50537 -34.08223 37.20494  1.000 136.17785 ? 170 GLU C OE1 1 
ATOM   5981 O OE2 . GLU C 1 210 ? -50.17196 -34.78354 35.22183  1.000 140.48484 ? 170 GLU C OE2 1 
ATOM   5982 N N   . GLY C 1 211 ? -48.48733 -28.65843 35.06556  1.000 137.74704 ? 171 GLY C N   1 
ATOM   5983 C CA  . GLY C 1 211 ? -48.82602 -27.76296 33.97686  1.000 130.94376 ? 171 GLY C CA  1 
ATOM   5984 C C   . GLY C 1 211 ? -47.60896 -27.36255 33.16887  1.000 126.68510 ? 171 GLY C C   1 
ATOM   5985 O O   . GLY C 1 211 ? -47.74888 -26.89543 32.03236  1.000 125.88842 ? 171 GLY C O   1 
ATOM   5986 N N   . VAL C 1 212 ? -46.41819 -27.52693 33.74082  1.000 129.06249 ? 172 VAL C N   1 
ATOM   5987 C CA  . VAL C 1 212 ? -45.21624 -27.86891 32.99180  1.000 125.94823 ? 172 VAL C CA  1 
ATOM   5988 C C   . VAL C 1 212 ? -44.81379 -29.24415 33.51087  1.000 120.53532 ? 172 VAL C C   1 
ATOM   5989 O O   . VAL C 1 212 ? -43.99549 -29.36580 34.42556  1.000 116.52465 ? 172 VAL C O   1 
ATOM   5990 C CB  . VAL C 1 212 ? -44.09245 -26.84444 33.16088  1.000 115.88227 ? 172 VAL C CB  1 
ATOM   5991 C CG1 . VAL C 1 212 ? -43.08359 -26.99532 32.04912  1.000 105.97505 ? 172 VAL C CG1 1 
ATOM   5992 C CG2 . VAL C 1 212 ? -44.65611 -25.42045 33.20212  1.000 105.21871 ? 172 VAL C CG2 1 
ATOM   5993 N N   . LYS C 1 213 ? -45.39194 -30.29728 32.93242  1.000 112.26026 ? 173 LYS C N   1 
ATOM   5994 C CA  . LYS C 1 213 ? -45.01992 -31.65005 33.33759  1.000 116.37349 ? 173 LYS C CA  1 
ATOM   5995 C C   . LYS C 1 213 ? -43.64965 -32.02211 32.79078  1.000 114.39991 ? 173 LYS C C   1 
ATOM   5996 O O   . LYS C 1 213 ? -42.81969 -32.60061 33.50389  1.000 117.89065 ? 173 LYS C O   1 
ATOM   5997 C CB  . LYS C 1 213 ? -46.08043 -32.65124 32.87354  1.000 116.94865 ? 173 LYS C CB  1 
ATOM   5998 C CG  . LYS C 1 213 ? -45.79636 -34.09172 33.25228  1.000 122.41730 ? 173 LYS C CG  1 
ATOM   5999 C CD  . LYS C 1 213 ? -46.80160 -35.04058 32.61035  1.000 115.91731 ? 173 LYS C CD  1 
ATOM   6000 C CE  . LYS C 1 213 ? -46.55314 -36.48619 33.02118  1.000 116.20728 ? 173 LYS C CE  1 
ATOM   6001 N NZ  . LYS C 1 213 ? -47.39492 -37.44124 32.24599  1.000 121.03919 ? 173 LYS C NZ  1 
ATOM   6002 N N   . ASP C 1 214 ? -43.41067 -31.70121 31.52530  1.000 105.27318 ? 174 ASP C N   1 
ATOM   6003 C CA  . ASP C 1 214 ? -42.09949 -31.80234 30.91431  1.000 100.62146 ? 174 ASP C CA  1 
ATOM   6004 C C   . ASP C 1 214 ? -41.95203 -30.63213 29.95654  1.000 104.11464 ? 174 ASP C C   1 
ATOM   6005 O O   . ASP C 1 214 ? -42.93679 -30.00125 29.56369  1.000 100.35544 ? 174 ASP C O   1 
ATOM   6006 C CB  . ASP C 1 214 ? -41.91148 -33.13436 30.17947  1.000 93.01962  ? 174 ASP C CB  1 
ATOM   6007 C CG  . ASP C 1 214 ? -40.45528 -33.52173 30.04585  1.000 97.33048  ? 174 ASP C CG  1 
ATOM   6008 O OD1 . ASP C 1 214 ? -39.58709 -32.68626 30.37224  1.000 99.13977  ? 174 ASP C OD1 1 
ATOM   6009 O OD2 . ASP C 1 214 ? -40.17985 -34.66019 29.61419  1.000 98.92967  ? 174 ASP C OD2 1 
ATOM   6010 N N   . ALA C 1 215 ? -40.71135 -30.33930 29.58173  1.000 91.86777  ? 175 ALA C N   1 
ATOM   6011 C CA  . ALA C 1 215 ? -40.46633 -29.20868 28.70341  1.000 80.91458  ? 175 ALA C CA  1 
ATOM   6012 C C   . ALA C 1 215 ? -39.20812 -29.45562 27.88994  1.000 77.16843  ? 175 ALA C C   1 
ATOM   6013 O O   . ALA C 1 215 ? -38.25490 -30.08351 28.35971  1.000 79.89681  ? 175 ALA C O   1 
ATOM   6014 C CB  . ALA C 1 215 ? -40.33548 -27.90136 29.49475  1.000 94.20277  ? 175 ALA C CB  1 
ATOM   6015 N N   . LEU C 1 216 ? -39.22215 -28.95164 26.65933  1.000 78.85136  ? 176 LEU C N   1 
ATOM   6016 C CA  . LEU C 1 216 ? -38.04957 -28.93781 25.79654  1.000 75.38127  ? 176 LEU C CA  1 
ATOM   6017 C C   . LEU C 1 216 ? -37.82567 -27.50553 25.34245  1.000 69.31320  ? 176 LEU C C   1 
ATOM   6018 O O   . LEU C 1 216 ? -38.71209 -26.90145 24.72909  1.000 68.58402  ? 176 LEU C O   1 
ATOM   6019 C CB  . LEU C 1 216 ? -38.23241 -29.86499 24.59153  1.000 57.49878  ? 176 LEU C CB  1 
ATOM   6020 C CG  . LEU C 1 216 ? -37.13301 -29.81086 23.52999  1.000 65.95304  ? 176 LEU C CG  1 
ATOM   6021 C CD1 . LEU C 1 216 ? -35.79875 -30.21805 24.12744  1.000 71.89289  ? 176 LEU C CD1 1 
ATOM   6022 C CD2 . LEU C 1 216 ? -37.48333 -30.68872 22.34172  1.000 63.15238  ? 176 LEU C CD2 1 
ATOM   6023 N N   . ALA C 1 217 ? -36.64794 -26.96731 25.63927  1.000 70.87451  ? 177 ALA C N   1 
ATOM   6024 C CA  . ALA C 1 217 ? -36.28290 -25.61170 25.25637  1.000 68.60530  ? 177 ALA C CA  1 
ATOM   6025 C C   . ALA C 1 217 ? -35.17778 -25.67870 24.21546  1.000 68.91366  ? 177 ALA C C   1 
ATOM   6026 O O   . ALA C 1 217 ? -34.16604 -26.35805 24.42056  1.000 65.13360  ? 177 ALA C O   1 
ATOM   6027 C CB  . ALA C 1 217 ? -35.82684 -24.79566 26.46790  1.000 68.73590  ? 177 ALA C CB  1 
ATOM   6028 N N   . LEU C 1 218 ? -35.37156 -24.97587 23.10599  1.000 65.83092  ? 178 LEU C N   1 
ATOM   6029 C CA  . LEU C 1 218 ? -34.41867 -24.97317 22.00919  1.000 61.56665  ? 178 LEU C CA  1 
ATOM   6030 C C   . LEU C 1 218 ? -33.80811 -23.59010 21.84605  1.000 66.67797  ? 178 LEU C C   1 
ATOM   6031 O O   . LEU C 1 218 ? -34.50177 -22.57468 21.96563  1.000 68.54483  ? 178 LEU C O   1 
ATOM   6032 C CB  . LEU C 1 218 ? -35.08509 -25.39059 20.69453  1.000 58.47151  ? 178 LEU C CB  1 
ATOM   6033 C CG  . LEU C 1 218 ? -35.70551 -26.78255 20.58233  1.000 63.02575  ? 178 LEU C CG  1 
ATOM   6034 C CD1 . LEU C 1 218 ? -36.11914 -27.05565 19.14141  1.000 50.29855  ? 178 LEU C CD1 1 
ATOM   6035 C CD2 . LEU C 1 218 ? -34.74941 -27.85175 21.08757  1.000 47.42686  ? 178 LEU C CD2 1 
ATOM   6036 N N   . ILE C 1 219 ? -32.50730 -23.55884 21.57631  1.000 64.46957  ? 179 ILE C N   1 
ATOM   6037 C CA  . ILE C 1 219 ? -31.82778 -22.35408 21.12376  1.000 59.46667  ? 179 ILE C CA  1 
ATOM   6038 C C   . ILE C 1 219 ? -31.78828 -22.40714 19.60242  1.000 60.85541  ? 179 ILE C C   1 
ATOM   6039 O O   . ILE C 1 219 ? -31.45786 -23.44639 19.01719  1.000 51.94283  ? 179 ILE C O   1 
ATOM   6040 C CB  . ILE C 1 219 ? -30.41851 -22.22874 21.73340  1.000 68.09834  ? 179 ILE C CB  1 
ATOM   6041 C CG1 . ILE C 1 219 ? -29.76140 -20.91361 21.30142  1.000 60.36314  ? 179 ILE C CG1 1 
ATOM   6042 C CG2 . ILE C 1 219 ? -29.54977 -23.43172 21.38912  1.000 61.96580  ? 179 ILE C CG2 1 
ATOM   6043 C CD1 . ILE C 1 219 ? -28.40203 -20.66705 21.92727  1.000 70.25001  ? 179 ILE C CD1 1 
ATOM   6044 N N   . ILE C 1 220 ? -32.15995 -21.30108 18.96464  1.000 54.40054  ? 180 ILE C N   1 
ATOM   6045 C CA  . ILE C 1 220 ? -32.29321 -21.24355 17.50705  1.000 57.37632  ? 180 ILE C CA  1 
ATOM   6046 C C   . ILE C 1 220 ? -31.48263 -20.06568 17.02340  1.000 65.72415  ? 180 ILE C C   1 
ATOM   6047 O O   . ILE C 1 220 ? -31.68370 -18.93145 17.46486  1.000 64.61059  ? 180 ILE C O   1 
ATOM   6048 C CB  . ILE C 1 220 ? -33.76330 -21.09350 17.06991  1.000 64.45625  ? 180 ILE C CB  1 
ATOM   6049 C CG1 . ILE C 1 220 ? -34.59470 -22.29217 17.53049  1.000 61.47929  ? 180 ILE C CG1 1 
ATOM   6050 C CG2 . ILE C 1 220 ? -33.84762 -20.93560 15.55962  1.000 57.88687  ? 180 ILE C CG2 1 
ATOM   6051 C CD1 . ILE C 1 220 ? -34.12047 -23.61868 16.98240  1.000 71.56124  ? 180 ILE C CD1 1 
ATOM   6052 N N   . PRO C 1 221 ? -30.53416 -20.25831 16.09578  1.000 69.31836  ? 181 PRO C N   1 
ATOM   6053 C CA  . PRO C 1 221 ? -29.76961 -19.12128 15.58651  1.000 61.94162  ? 181 PRO C CA  1 
ATOM   6054 C C   . PRO C 1 221 ? -30.57324 -18.36628 14.54221  1.000 60.62318  ? 181 PRO C C   1 
ATOM   6055 O O   . PRO C 1 221 ? -31.22581 -18.95912 13.67962  1.000 58.62112  ? 181 PRO C O   1 
ATOM   6056 C CB  . PRO C 1 221 ? -28.53071 -19.78159 14.97336  1.000 53.64107  ? 181 PRO C CB  1 
ATOM   6057 C CG  . PRO C 1 221 ? -29.04605 -21.09890 14.48147  1.000 67.00574  ? 181 PRO C CG  1 
ATOM   6058 C CD  . PRO C 1 221 ? -30.14859 -21.52150 15.43974  1.000 63.10342  ? 181 PRO C CD  1 
ATOM   6059 N N   . ILE C 1 222 ? -30.52639 -17.03893 14.63133  1.000 70.53980  ? 182 ILE C N   1 
ATOM   6060 C CA  . ILE C 1 222 ? -31.18501 -16.17158 13.66739  1.000 64.21828  ? 182 ILE C CA  1 
ATOM   6061 C C   . ILE C 1 222 ? -30.19171 -15.28751 12.92780  1.000 61.69730  ? 182 ILE C C   1 
ATOM   6062 O O   . ILE C 1 222 ? -30.59500 -14.37051 12.21153  1.000 67.88697  ? 182 ILE C O   1 
ATOM   6063 C CB  . ILE C 1 222 ? -32.28414 -15.32607 14.33995  1.000 62.93429  ? 182 ILE C CB  1 
ATOM   6064 C CG1 . ILE C 1 222 ? -31.69688 -14.49813 15.48189  1.000 70.98532  ? 182 ILE C CG1 1 
ATOM   6065 C CG2 . ILE C 1 222 ? -33.39638 -16.22390 14.85803  1.000 64.31298  ? 182 ILE C CG2 1 
ATOM   6066 C CD1 . ILE C 1 222 ? -32.66509 -13.50168 16.06918  1.000 59.72032  ? 182 ILE C CD1 1 
ATOM   6067 N N   . GLY C 1 223 ? -28.90262 -15.54444 13.08876  1.000 65.48808  ? 183 GLY C N   1 
ATOM   6068 C CA  . GLY C 1 223 ? -27.85941 -14.84934 12.37073  1.000 55.87079  ? 183 GLY C CA  1 
ATOM   6069 C C   . GLY C 1 223 ? -27.10126 -13.87409 13.26138  1.000 57.54815  ? 183 GLY C C   1 
ATOM   6070 O O   . GLY C 1 223 ? -27.59500 -13.40961 14.29426  1.000 61.45743  ? 183 GLY C O   1 
ATOM   6071 N N   . THR C 1 224 ? -25.87987 -13.55617 12.82612  1.000 44.25215  ? 184 THR C N   1 
ATOM   6072 C CA  . THR C 1 224 ? -24.99571 -12.59024 13.47590  1.000 56.33228  ? 184 THR C CA  1 
ATOM   6073 C C   . THR C 1 224 ? -24.96052 -12.71684 14.99433  1.000 51.11018  ? 184 THR C C   1 
ATOM   6074 O O   . THR C 1 224 ? -25.02333 -11.70920 15.70664  1.000 58.62987  ? 184 THR C O   1 
ATOM   6075 C CB  . THR C 1 224 ? -25.39895 -11.16114 13.09862  1.000 63.68416  ? 184 THR C CB  1 
ATOM   6076 O OG1 . THR C 1 224 ? -26.73671 -10.90026 13.53962  1.000 67.27053  ? 184 THR C OG1 1 
ATOM   6077 C CG2 . THR C 1 224 ? -25.32327 -10.96709 11.59947  1.000 59.61922  ? 184 THR C CG2 1 
ATOM   6078 N N   . GLY C 1 225 ? -24.85552 -13.94369 15.49974  1.000 45.51885  ? 185 GLY C N   1 
ATOM   6079 C CA  . GLY C 1 225 ? -24.71245 -14.17094 16.92121  1.000 55.73112  ? 185 GLY C CA  1 
ATOM   6080 C C   . GLY C 1 225 ? -25.98176 -14.03068 17.72711  1.000 58.08873  ? 185 GLY C C   1 
ATOM   6081 O O   . GLY C 1 225 ? -25.97183 -14.34101 18.92498  1.000 58.17851  ? 185 GLY C O   1 
ATOM   6082 N N   . LEU C 1 226 ? -27.07506 -13.58922 17.11654  1.000 56.28184  ? 186 LEU C N   1 
ATOM   6083 C CA  . LEU C 1 226 ? -28.34032 -13.47162 17.81987  1.000 55.54391  ? 186 LEU C CA  1 
ATOM   6084 C C   . LEU C 1 226 ? -29.07007 -14.80886 17.80809  1.000 60.72118  ? 186 LEU C C   1 
ATOM   6085 O O   . LEU C 1 226 ? -28.94815 -15.59951 16.86760  1.000 67.81819  ? 186 LEU C O   1 
ATOM   6086 C CB  . LEU C 1 226 ? -29.20452 -12.38982 17.17511  1.000 59.33164  ? 186 LEU C CB  1 
ATOM   6087 C CG  . LEU C 1 226 ? -28.52826 -11.02780 17.00711  1.000 63.09121  ? 186 LEU C CG  1 
ATOM   6088 C CD1 . LEU C 1 226 ? -29.42731 -10.06432 16.24878  1.000 57.09768  ? 186 LEU C CD1 1 
ATOM   6089 C CD2 . LEU C 1 226 ? -28.13949 -10.44796 18.35866  1.000 55.66273  ? 186 LEU C CD2 1 
ATOM   6090 N N   . HIS C 1 227 ? -29.84190 -15.05882 18.86244  1.000 63.40667  ? 187 HIS C N   1 
ATOM   6091 C CA  . HIS C 1 227 ? -30.50259 -16.34644 19.00659  1.000 66.02362  ? 187 HIS C CA  1 
ATOM   6092 C C   . HIS C 1 227 ? -31.94050 -16.17214 19.46908  1.000 75.47673  ? 187 HIS C C   1 
ATOM   6093 O O   . HIS C 1 227 ? -32.24442 -15.29002 20.27690  1.000 76.83689  ? 187 HIS C O   1 
ATOM   6094 C CB  . HIS C 1 227 ? -29.73956 -17.24896 19.98032  1.000 53.98923  ? 187 HIS C CB  1 
ATOM   6095 C CG  . HIS C 1 227 ? -28.37297 -17.62303 19.50044  1.000 67.42587  ? 187 HIS C CG  1 
ATOM   6096 N ND1 . HIS C 1 227 ? -27.25042 -16.88111 19.79653  1.000 61.70645  ? 187 HIS C ND1 1 
ATOM   6097 C CD2 . HIS C 1 227 ? -27.95206 -18.64767 18.72221  1.000 64.80058  ? 187 HIS C CD2 1 
ATOM   6098 C CE1 . HIS C 1 227 ? -26.19438 -17.44105 19.23430  1.000 55.88839  ? 187 HIS C CE1 1 
ATOM   6099 N NE2 . HIS C 1 227 ? -26.59301 -18.51393 18.57572  1.000 61.22501  ? 187 HIS C NE2 1 
ATOM   6100 N N   . ARG C 1 228 ? -32.81298 -17.03406 18.95240  1.000 79.30690  ? 188 ARG C N   1 
ATOM   6101 C CA  . ARG C 1 228 ? -34.21094 -17.12191 19.34382  1.000 74.06014  ? 188 ARG C CA  1 
ATOM   6102 C C   . ARG C 1 228 ? -34.43937 -18.41037 20.12635  1.000 70.35417  ? 188 ARG C C   1 
ATOM   6103 O O   . ARG C 1 228 ? -33.76507 -19.41902 19.89941  1.000 69.17467  ? 188 ARG C O   1 
ATOM   6104 C CB  . ARG C 1 228 ? -35.11497 -17.08643 18.10420  1.000 77.64013  ? 188 ARG C CB  1 
ATOM   6105 C CG  . ARG C 1 228 ? -36.55572 -17.52605 18.32255  1.000 90.33013  ? 188 ARG C CG  1 
ATOM   6106 C CD  . ARG C 1 228 ? -37.04405 -18.31668 17.12590  1.000 90.84392  ? 188 ARG C CD  1 
ATOM   6107 N NE  . ARG C 1 228 ? -36.68054 -17.68042 15.86614  1.000 82.56407  ? 188 ARG C NE  1 
ATOM   6108 C CZ  . ARG C 1 228 ? -36.78045 -18.26577 14.68106  1.000 82.35638  ? 188 ARG C CZ  1 
ATOM   6109 N NH1 . ARG C 1 228 ? -37.21185 -19.51063 14.56057  1.000 63.34213  ? 188 ARG C NH1 1 
ATOM   6110 N NH2 . ARG C 1 228 ? -36.43339 -17.58769 13.59056  1.000 66.40787  ? 188 ARG C NH2 1 
ATOM   6111 N N   . ARG C 1 229 ? -35.39189 -18.36921 21.05475  1.000 75.53797  ? 189 ARG C N   1 
ATOM   6112 C CA  . ARG C 1 229 ? -35.72620 -19.50989 21.89479  1.000 77.30281  ? 189 ARG C CA  1 
ATOM   6113 C C   . ARG C 1 229 ? -37.08946 -20.07087 21.50514  1.000 84.34926  ? 189 ARG C C   1 
ATOM   6114 O O   . ARG C 1 229 ? -38.02911 -19.31590 21.23362  1.000 76.87118  ? 189 ARG C O   1 
ATOM   6115 C CB  . ARG C 1 229 ? -35.71754 -19.11060 23.37525  1.000 69.54934  ? 189 ARG C CB  1 
ATOM   6116 C CG  . ARG C 1 229 ? -35.37826 -20.23814 24.34405  1.000 84.42616  ? 189 ARG C CG  1 
ATOM   6117 C CD  . ARG C 1 229 ? -34.11796 -19.93333 25.14646  1.000 90.92214  ? 189 ARG C CD  1 
ATOM   6118 N NE  . ARG C 1 229 ? -33.91262 -18.50309 25.34432  1.000 86.46111  ? 189 ARG C NE  1 
ATOM   6119 C CZ  . ARG C 1 229 ? -32.93579 -17.98110 26.07405  1.000 87.51654  ? 189 ARG C CZ  1 
ATOM   6120 N NH1 . ARG C 1 229 ? -32.06246 -18.74613 26.70877  1.000 88.73511  ? 189 ARG C NH1 1 
ATOM   6121 N NH2 . ARG C 1 229 ? -32.82715 -16.65838 26.16227  1.000 101.41616 ? 189 ARG C NH2 1 
ATOM   6122 N N   . MET C 1 230 ? -37.18759 -21.40018 21.46941  1.000 70.05960  ? 190 MET C N   1 
ATOM   6123 C CA  . MET C 1 230 ? -38.44517 -22.09640 21.21788  1.000 79.81579  ? 190 MET C CA  1 
ATOM   6124 C C   . MET C 1 230 ? -38.66548 -23.11175 22.32666  1.000 76.33340  ? 190 MET C C   1 
ATOM   6125 O O   . MET C 1 230 ? -37.80395 -23.96216 22.57476  1.000 67.90692  ? 190 MET C O   1 
ATOM   6126 C CB  . MET C 1 230 ? -38.45350 -22.79041 19.85257  1.000 69.25377  ? 190 MET C CB  1 
ATOM   6127 C CG  . MET C 1 230 ? -38.83770 -21.88948 18.69262  1.000 93.30198  ? 190 MET C CG  1 
ATOM   6128 S SD  . MET C 1 230 ? -38.79211 -22.76504 17.11672  1.000 115.25532 ? 190 MET C SD  1 
ATOM   6129 C CE  . MET C 1 230 ? -40.24373 -22.08520 16.31900  1.000 90.05912  ? 190 MET C CE  1 
ATOM   6130 N N   . VAL C 1 231 ? -39.81503 -23.01950 22.98925  1.000 73.87368  ? 191 VAL C N   1 
ATOM   6131 C CA  . VAL C 1 231 ? -40.12824 -23.82743 24.16178  1.000 74.42140  ? 191 VAL C CA  1 
ATOM   6132 C C   . VAL C 1 231 ? -41.32714 -24.70273 23.83229  1.000 76.11435  ? 191 VAL C C   1 
ATOM   6133 O O   . VAL C 1 231 ? -42.38838 -24.19244 23.45254  1.000 75.28474  ? 191 VAL C O   1 
ATOM   6134 C CB  . VAL C 1 231 ? -40.41568 -22.95593 25.39472  1.000 76.49476  ? 191 VAL C CB  1 
ATOM   6135 C CG1 . VAL C 1 231 ? -40.41484 -23.80117 26.66192  1.000 71.60809  ? 191 VAL C CG1 1 
ATOM   6136 C CG2 . VAL C 1 231 ? -39.40307 -21.82588 25.49418  1.000 77.61478  ? 191 VAL C CG2 1 
ATOM   6137 N N   . TYR C 1 232 ? -41.16070 -26.01320 23.98002  1.000 72.12593  ? 192 TYR C N   1 
ATOM   6138 C CA  . TYR C 1 232 ? -42.25290 -26.97155 23.86772  1.000 69.42915  ? 192 TYR C CA  1 
ATOM   6139 C C   . TYR C 1 232 ? -42.59669 -27.45879 25.26831  1.000 77.01824  ? 192 TYR C C   1 
ATOM   6140 O O   . TYR C 1 232 ? -41.72312 -27.95369 25.98755  1.000 74.44155  ? 192 TYR C O   1 
ATOM   6141 C CB  . TYR C 1 232 ? -41.87966 -28.13818 22.95302  1.000 59.04216  ? 192 TYR C CB  1 
ATOM   6142 C CG  . TYR C 1 232 ? -41.44159 -27.70848 21.57226  1.000 65.76058  ? 192 TYR C CG  1 
ATOM   6143 C CD1 . TYR C 1 232 ? -42.37489 -27.45561 20.57676  1.000 61.78532  ? 192 TYR C CD1 1 
ATOM   6144 C CD2 . TYR C 1 232 ? -40.09606 -27.56049 21.26175  1.000 65.99310  ? 192 TYR C CD2 1 
ATOM   6145 C CE1 . TYR C 1 232 ? -41.98313 -27.06149 19.31137  1.000 66.80206  ? 192 TYR C CE1 1 
ATOM   6146 C CE2 . TYR C 1 232 ? -39.69447 -27.16761 19.99846  1.000 54.69251  ? 192 TYR C CE2 1 
ATOM   6147 C CZ  . TYR C 1 232 ? -40.64227 -26.91947 19.02656  1.000 59.91540  ? 192 TYR C CZ  1 
ATOM   6148 O OH  . TYR C 1 232 ? -40.24884 -26.52774 17.76656  1.000 66.20181  ? 192 TYR C OH  1 
ATOM   6149 N N   . VAL C 1 233 ? -43.86208 -27.31686 25.65084  1.000 86.58423  ? 193 VAL C N   1 
ATOM   6150 C CA  . VAL C 1 233 ? -44.31001 -27.53703 27.02019  1.000 92.59593  ? 193 VAL C CA  1 
ATOM   6151 C C   . VAL C 1 233 ? -45.39121 -28.60945 27.02732  1.000 87.34144  ? 193 VAL C C   1 
ATOM   6152 O O   . VAL C 1 233 ? -46.26774 -28.62777 26.15532  1.000 74.05554  ? 193 VAL C O   1 
ATOM   6153 C CB  . VAL C 1 233 ? -44.82079 -26.22884 27.66428  1.000 83.00680  ? 193 VAL C CB  1 
ATOM   6154 C CG1 . VAL C 1 233 ? -45.97872 -25.64035 26.86027  1.000 72.07417  ? 193 VAL C CG1 1 
ATOM   6155 C CG2 . VAL C 1 233 ? -45.21896 -26.46130 29.11585  1.000 85.99885  ? 193 VAL C CG2 1 
ATOM   6156 N N   . GLU C 1 234 ? -45.30828 -29.52327 27.99515  1.000 88.20934  ? 194 GLU C N   1 
ATOM   6157 C CA  . GLU C 1 234 ? -46.37946 -30.48333 28.24146  1.000 93.49624  ? 194 GLU C CA  1 
ATOM   6158 C C   . GLU C 1 234 ? -47.27713 -29.90611 29.32862  1.000 97.37197  ? 194 GLU C C   1 
ATOM   6159 O O   . GLU C 1 234 ? -46.89526 -29.85694 30.50321  1.000 104.84166 ? 194 GLU C O   1 
ATOM   6160 C CB  . GLU C 1 234 ? -45.82065 -31.83962 28.66703  1.000 95.69825  ? 194 GLU C CB  1 
ATOM   6161 C CG  . GLU C 1 234 ? -45.70947 -32.87238 27.55801  1.000 82.80677  ? 194 GLU C CG  1 
ATOM   6162 C CD  . GLU C 1 234 ? -45.43736 -34.26634 28.09860  1.000 97.89402  ? 194 GLU C CD  1 
ATOM   6163 O OE1 . GLU C 1 234 ? -46.27589 -34.78040 28.86847  1.000 97.34375  ? 194 GLU C OE1 1 
ATOM   6164 O OE2 . GLU C 1 234 ? -44.38174 -34.84308 27.76418  1.000 95.15552  ? 194 GLU C OE2 1 
ATOM   6165 N N   . LEU C 1 235 ? -48.46866 -29.47212 28.93404  1.000 99.33442  ? 195 LEU C N   1 
ATOM   6166 C CA  . LEU C 1 235 ? -49.36967 -28.76061 29.83010  1.000 95.98333  ? 195 LEU C CA  1 
ATOM   6167 C C   . LEU C 1 235 ? -50.24569 -29.73081 30.61616  1.000 103.74761 ? 195 LEU C C   1 
ATOM   6168 O O   . LEU C 1 235 ? -50.49641 -29.53004 31.80346  1.000 108.25540 ? 195 LEU C O   1 
ATOM   6169 C CB  . LEU C 1 235 ? -50.22195 -27.77038 29.03233  1.000 91.30361  ? 195 LEU C CB  1 
ATOM   6170 C CG  . LEU C 1 235 ? -51.14527 -26.79218 29.76110  1.000 94.64568  ? 195 LEU C CG  1 
ATOM   6171 C CD1 . LEU C 1 235 ? -50.51105 -26.28860 31.02829  1.000 104.15343 ? 195 LEU C CD1 1 
ATOM   6172 C CD2 . LEU C 1 235 ? -51.46690 -25.61774 28.85946  1.000 95.47109  ? 195 LEU C CD2 1 
ATOM   6173 N N   . GLU C 1 237 ? -52.30125 -30.86314 33.37581  1.000 111.25692 ? 197 GLU C N   1 
ATOM   6174 C CA  . GLU C 1 237 ? -53.71919 -31.14242 33.45703  1.000 109.21623 ? 197 GLU C CA  1 
ATOM   6175 C C   . GLU C 1 237 ? -54.52679 -29.87703 33.21049  1.000 116.06436 ? 197 GLU C C   1 
ATOM   6176 O O   . GLU C 1 237 ? -54.29255 -29.17655 32.22794  1.000 121.10481 ? 197 GLU C O   1 
ATOM   6177 C CB  . GLU C 1 237 ? -54.04520 -31.72008 34.81713  1.000 109.00117 ? 197 GLU C CB  1 
ATOM   6178 C CG  . GLU C 1 237 ? -53.44153 -33.07559 34.98650  1.000 126.90152 ? 197 GLU C CG  1 
ATOM   6179 C CD  . GLU C 1 237 ? -53.20358 -33.43287 36.42803  1.000 133.76713 ? 197 GLU C CD  1 
ATOM   6180 O OE1 . GLU C 1 237 ? -52.99027 -32.52236 37.26295  1.000 130.97327 ? 197 GLU C OE1 1 
ATOM   6181 O OE2 . GLU C 1 237 ? -53.21087 -34.64298 36.71162  1.000 130.41405 ? 197 GLU C OE2 1 
ATOM   6182 N N   . GLY C 1 238 ? -55.41680 -29.54565 34.14781  1.000 103.80881 ? 198 GLY C N   1 
ATOM   6183 C CA  . GLY C 1 238 ? -56.28568 -28.39392 33.99555  1.000 100.33895 ? 198 GLY C CA  1 
ATOM   6184 C C   . GLY C 1 238 ? -55.57915 -27.07979 34.23707  1.000 107.50649 ? 198 GLY C C   1 
ATOM   6185 O O   . GLY C 1 238 ? -55.64055 -26.50844 35.32821  1.000 113.82127 ? 198 GLY C O   1 
ATOM   6186 N N   . ALA C 1 239 ? -54.88032 -26.60474 33.21658  1.000 113.06357 ? 199 ALA C N   1 
ATOM   6187 C CA  . ALA C 1 239 ? -54.17914 -25.33499 33.26806  1.000 111.75493 ? 199 ALA C CA  1 
ATOM   6188 C C   . ALA C 1 239 ? -54.32793 -24.65241 31.91697  1.000 109.95265 ? 199 ALA C C   1 
ATOM   6189 O O   . ALA C 1 239 ? -54.45842 -25.31298 30.88317  1.000 101.85503 ? 199 ALA C O   1 
ATOM   6190 C CB  . ALA C 1 239 ? -52.70403 -25.53314 33.63235  1.000 100.53863 ? 199 ALA C CB  1 
ATOM   6191 N N   . ASP C 1 240 ? -54.29174 -23.32587 31.92703  1.000 106.12527 ? 200 ASP C N   1 
ATOM   6192 C CA  . ASP C 1 240 ? -54.51238 -22.55523 30.71537  1.000 108.02700 ? 200 ASP C CA  1 
ATOM   6193 C C   . ASP C 1 240 ? -53.19784 -22.27508 30.00473  1.000 111.89186 ? 200 ASP C C   1 
ATOM   6194 O O   . ASP C 1 240 ? -52.19274 -21.93464 30.63540  1.000 112.44072 ? 200 ASP C O   1 
ATOM   6195 C CB  . ASP C 1 240 ? -55.22076 -21.24285 31.05217  1.000 96.86527  ? 200 ASP C CB  1 
ATOM   6196 C CG  . ASP C 1 240 ? -55.45194 -20.37346 29.83453  1.000 109.92909 ? 200 ASP C CG  1 
ATOM   6197 O OD1 . ASP C 1 240 ? -55.59721 -20.92330 28.72047  1.000 108.67054 ? 200 ASP C OD1 1 
ATOM   6198 O OD2 . ASP C 1 240 ? -55.48614 -19.13407 29.99205  1.000 113.96518 ? 200 ASP C OD2 1 
ATOM   6199 N N   . PHE C 1 241 ? -53.22276 -22.42045 28.67726  1.000 110.48989 ? 201 PHE C N   1 
ATOM   6200 C CA  . PHE C 1 241 ? -52.02344 -22.20064 27.87826  1.000 101.73214 ? 201 PHE C CA  1 
ATOM   6201 C C   . PHE C 1 241 ? -51.61800 -20.73431 27.90742  1.000 109.55222 ? 201 PHE C C   1 
ATOM   6202 O O   . PHE C 1 241 ? -50.42381 -20.41329 27.93806  1.000 107.77661 ? 201 PHE C O   1 
ATOM   6203 C CB  . PHE C 1 241 ? -52.24683 -22.68169 26.44547  1.000 89.04997  ? 201 PHE C CB  1 
ATOM   6204 C CG  . PHE C 1 241 ? -51.01436 -22.62332 25.58642  1.000 97.82955  ? 201 PHE C CG  1 
ATOM   6205 C CD1 . PHE C 1 241 ? -49.84301 -23.24356 25.98980  1.000 100.66407 ? 201 PHE C CD1 1 
ATOM   6206 C CD2 . PHE C 1 241 ? -51.02967 -21.95957 24.36922  1.000 102.22996 ? 201 PHE C CD2 1 
ATOM   6207 C CE1 . PHE C 1 241 ? -48.70676 -23.19807 25.20249  1.000 95.04887  ? 201 PHE C CE1 1 
ATOM   6208 C CE2 . PHE C 1 241 ? -49.89461 -21.91094 23.57543  1.000 97.21435  ? 201 PHE C CE2 1 
ATOM   6209 C CZ  . PHE C 1 241 ? -48.73197 -22.53121 23.99340  1.000 93.09790  ? 201 PHE C CZ  1 
ATOM   6210 N N   . ALA C 1 242 ? -52.60066 -19.83095 27.85591  1.000 106.05022 ? 202 ALA C N   1 
ATOM   6211 C CA  . ALA C 1 242 ? -52.29393 -18.40601 27.85814  1.000 110.00629 ? 202 ALA C CA  1 
ATOM   6212 C C   . ALA C 1 242 ? -51.55504 -18.00995 29.12991  1.000 109.65585 ? 202 ALA C C   1 
ATOM   6213 O O   . ALA C 1 242 ? -50.66982 -17.15126 29.09476  1.000 100.60888 ? 202 ALA C O   1 
ATOM   6214 C CB  . ALA C 1 242 ? -53.57443 -17.58466 27.69541  1.000 115.04343 ? 202 ALA C CB  1 
ATOM   6215 N N   . THR C 1 243 ? -51.88341 -18.63988 30.26158  1.000 107.38077 ? 203 THR C N   1 
ATOM   6216 C CA  . THR C 1 243 ? -51.20034 -18.29313 31.50561  1.000 111.26201 ? 203 THR C CA  1 
ATOM   6217 C C   . THR C 1 243 ? -49.78876 -18.86913 31.54781  1.000 112.05915 ? 203 THR C C   1 
ATOM   6218 O O   . THR C 1 243 ? -48.82982 -18.14556 31.83638  1.000 114.97099 ? 203 THR C O   1 
ATOM   6219 C CB  . THR C 1 243 ? -51.99807 -18.77163 32.72100  1.000 109.44964 ? 203 THR C CB  1 
ATOM   6220 O OG1 . THR C 1 243 ? -53.28069 -19.25454 32.30683  1.000 103.37535 ? 203 THR C OG1 1 
ATOM   6221 C CG2 . THR C 1 243 ? -52.17745 -17.63782 33.72512  1.000 110.25752 ? 203 THR C CG2 1 
ATOM   6222 N N   . VAL C 1 244 ? -49.63285 -20.16500 31.24486  1.000 107.35376 ? 204 VAL C N   1 
ATOM   6223 C CA  . VAL C 1 244 ? -48.29714 -20.76316 31.29350  1.000 102.94272 ? 204 VAL C CA  1 
ATOM   6224 C C   . VAL C 1 244 ? -47.38354 -20.12248 30.26273  1.000 98.18068  ? 204 VAL C C   1 
ATOM   6225 O O   . VAL C 1 244 ? -46.17312 -19.99313 30.49044  1.000 102.31441 ? 204 VAL C O   1 
ATOM   6226 C CB  . VAL C 1 244 ? -48.35500 -22.29396 31.11559  1.000 104.15369 ? 204 VAL C CB  1 
ATOM   6227 C CG1 . VAL C 1 244 ? -48.98134 -22.94642 32.34214  1.000 101.03958 ? 204 VAL C CG1 1 
ATOM   6228 C CG2 . VAL C 1 244 ? -49.09244 -22.67464 29.84554  1.000 107.12399 ? 204 VAL C CG2 1 
ATOM   6229 N N   . LYS C 1 245 ? -47.93653 -19.70268 29.12208  1.000 95.56662  ? 205 LYS C N   1 
ATOM   6230 C CA  . LYS C 1 245 ? -47.15883 -18.88239 28.20270  1.000 93.72052  ? 205 LYS C CA  1 
ATOM   6231 C C   . LYS C 1 245 ? -46.76893 -17.57461 28.87824  1.000 108.94370 ? 205 LYS C C   1 
ATOM   6232 O O   . LYS C 1 245 ? -45.61434 -17.13883 28.80726  1.000 115.34173 ? 205 LYS C O   1 
ATOM   6233 C CB  . LYS C 1 245 ? -47.95647 -18.59496 26.92861  1.000 92.43864  ? 205 LYS C CB  1 
ATOM   6234 C CG  . LYS C 1 245 ? -47.65666 -19.48255 25.73826  1.000 87.36624  ? 205 LYS C CG  1 
ATOM   6235 C CD  . LYS C 1 245 ? -48.20878 -18.84144 24.46775  1.000 84.27996  ? 205 LYS C CD  1 
ATOM   6236 C CE  . LYS C 1 245 ? -47.67409 -17.42111 24.28734  1.000 67.73484  ? 205 LYS C CE  1 
ATOM   6237 N NZ  . LYS C 1 245 ? -48.11002 -16.80558 23.00194  1.000 76.25574  ? 205 LYS C NZ  1 
ATOM   6238 N N   . GLU C 1 246 ? -47.71946 -16.94888 29.57577  1.000 111.64349 ? 206 GLU C N   1 
ATOM   6239 C CA  . GLU C 1 246 ? -47.43126 -15.69105 30.24819  1.000 115.52120 ? 206 GLU C CA  1 
ATOM   6240 C C   . GLU C 1 246 ? -46.81930 -15.91572 31.62864  1.000 117.58471 ? 206 GLU C C   1 
ATOM   6241 O O   . GLU C 1 246 ? -47.03641 -15.11437 32.53970  1.000 131.34871 ? 206 GLU C O   1 
ATOM   6242 C CB  . GLU C 1 246 ? -48.68236 -14.81407 30.30240  1.000 123.99664 ? 206 GLU C CB  1 
ATOM   6243 C CG  . GLU C 1 246 ? -49.28499 -14.55384 28.92281  1.000 122.70110 ? 206 GLU C CG  1 
ATOM   6244 C CD  . GLU C 1 246 ? -48.24864 -14.15679 27.88788  1.000 117.33092 ? 206 GLU C CD  1 
ATOM   6245 O OE1 . GLU C 1 246 ? -47.52388 -13.17759 28.14022  1.000 119.65698 ? 206 GLU C OE1 1 
ATOM   6246 O OE2 . GLU C 1 246 ? -48.16507 -14.81067 26.82416  1.000 114.59256 ? 206 GLU C OE2 1 
ATOM   6247 N N   . ARG C 1 247 ? -46.06558 -17.00609 31.79963  1.000 112.74598 ? 207 ARG C N   1 
ATOM   6248 C CA  . ARG C 1 247 ? -45.30676 -17.22137 33.02871  1.000 111.74531 ? 207 ARG C CA  1 
ATOM   6249 C C   . ARG C 1 247 ? -43.83829 -17.43251 32.68054  1.000 127.23063 ? 207 ARG C C   1 
ATOM   6250 O O   . ARG C 1 247 ? -42.94065 -17.04286 33.43544  1.000 134.37356 ? 207 ARG C O   1 
ATOM   6251 C CB  . ARG C 1 247 ? -45.85474 -18.43228 33.78234  1.000 113.92750 ? 207 ARG C CB  1 
ATOM   6252 C CG  . ARG C 1 247 ? -47.23387 -18.22748 34.37440  1.000 115.40402 ? 207 ARG C CG  1 
ATOM   6253 C CD  . ARG C 1 247 ? -47.86453 -19.57925 34.66395  1.000 111.04325 ? 207 ARG C CD  1 
ATOM   6254 N NE  . ARG C 1 247 ? -49.20593 -19.49913 35.22929  1.000 109.73570 ? 207 ARG C NE  1 
ATOM   6255 C CZ  . ARG C 1 247 ? -49.49238 -19.66814 36.51121  1.000 111.52974 ? 207 ARG C CZ  1 
ATOM   6256 N NH1 . ARG C 1 247 ? -48.54947 -19.93367 37.39916  1.000 115.59843 ? 207 ARG C NH1 1 
ATOM   6257 N NH2 . ARG C 1 247 ? -50.76010 -19.59773 36.90704  1.000 96.33628  ? 207 ARG C NH2 1 
ATOM   6258 N N   . ILE C 1 248 ? -43.59997 -18.04933 31.52652  1.000 125.33264 ? 208 ILE C N   1 
ATOM   6259 C CA  . ILE C 1 248 ? -42.26439 -18.19150 30.95654  1.000 121.47054 ? 208 ILE C CA  1 
ATOM   6260 C C   . ILE C 1 248 ? -41.89869 -16.99932 30.07493  1.000 114.50536 ? 208 ILE C C   1 
ATOM   6261 O O   . ILE C 1 248 ? -40.75243 -16.54470 30.08791  1.000 115.90533 ? 208 ILE C O   1 
ATOM   6262 C CB  . ILE C 1 248 ? -42.15522 -19.53580 30.20609  1.000 117.16372 ? 208 ILE C CB  1 
ATOM   6263 C CG1 . ILE C 1 248 ? -42.23069 -20.68979 31.21162  1.000 119.00231 ? 208 ILE C CG1 1 
ATOM   6264 C CG2 . ILE C 1 248 ? -40.86493 -19.62166 29.40197  1.000 111.81021 ? 208 ILE C CG2 1 
ATOM   6265 C CD1 . ILE C 1 248 ? -42.30311 -22.06986 30.58531  1.000 106.49903 ? 208 ILE C CD1 1 
ATOM   6266 N N   . LEU C 1 249 ? -42.84554 -16.47246 29.28753  1.000 109.30032 ? 209 LEU C N   1 
ATOM   6267 C CA  . LEU C 1 249 ? -42.52078 -15.35112 28.40843  1.000 105.46630 ? 209 LEU C CA  1 
ATOM   6268 C C   . LEU C 1 249 ? -42.20066 -14.07945 29.19766  1.000 120.52275 ? 209 LEU C C   1 
ATOM   6269 O O   . LEU C 1 249 ? -41.56772 -13.16467 28.64907  1.000 113.91224 ? 209 LEU C O   1 
ATOM   6270 C CB  . LEU C 1 249 ? -43.65937 -15.08303 27.42303  1.000 108.63590 ? 209 LEU C CB  1 
ATOM   6271 C CG  . LEU C 1 249 ? -43.53792 -15.59126 25.97204  1.000 102.79977 ? 209 LEU C CG  1 
ATOM   6272 C CD1 . LEU C 1 249 ? -44.83365 -15.36791 25.18890  1.000 97.87778  ? 209 LEU C CD1 1 
ATOM   6273 C CD2 . LEU C 1 249 ? -42.37738 -14.93027 25.25605  1.000 100.37545 ? 209 LEU C CD2 1 
ATOM   6274 N N   . GLN C 1 250 ? -42.60917 -14.01220 30.47394  1.000 129.14661 ? 210 GLN C N   1 
ATOM   6275 C CA  . GLN C 1 250 ? -42.21814 -12.95873 31.40286  1.000 128.50322 ? 210 GLN C CA  1 
ATOM   6276 C C   . GLN C 1 250 ? -41.21323 -13.46509 32.42540  1.000 121.52265 ? 210 GLN C C   1 
ATOM   6277 O O   . GLN C 1 250 ? -40.93532 -12.76755 33.40137  1.000 117.95699 ? 210 GLN C O   1 
ATOM   6278 C CB  . GLN C 1 250 ? -43.44970 -12.40980 32.11270  1.000 123.05494 ? 210 GLN C CB  1 
ATOM   6279 C CG  . GLN C 1 250 ? -44.26886 -11.50887 31.23697  1.000 116.67736 ? 210 GLN C CG  1 
ATOM   6280 C CD  . GLN C 1 250 ? -45.21585 -12.29960 30.37625  1.000 133.16802 ? 210 GLN C CD  1 
ATOM   6281 O OE1 . GLN C 1 250 ? -45.26756 -13.53060 30.45967  1.000 132.93332 ? 210 GLN C OE1 1 
ATOM   6282 N NE2 . GLN C 1 250 ? -45.99470 -11.60512 29.56921  1.000 131.65784 ? 210 GLN C NE2 1 
ATOM   6283 N N   . ASP C 1 251 ? -40.72527 -14.69542 32.26046  1.000 118.28457 ? 211 ASP C N   1 
ATOM   6284 C CA  . ASP C 1 251 ? -39.63556 -15.18943 33.08852  1.000 121.23078 ? 211 ASP C CA  1 
ATOM   6285 C C   . ASP C 1 251 ? -38.35718 -14.42160 32.76326  1.000 125.08048 ? 211 ASP C C   1 
ATOM   6286 O O   . ASP C 1 251 ? -38.12368 -14.07618 31.60220  1.000 121.26334 ? 211 ASP C O   1 
ATOM   6287 C CB  . ASP C 1 251 ? -39.42046 -16.69848 32.86521  1.000 115.40580 ? 211 ASP C CB  1 
ATOM   6288 C CG  . ASP C 1 251 ? -38.46024 -17.32001 33.87879  1.000 117.68851 ? 211 ASP C CG  1 
ATOM   6289 O OD1 . ASP C 1 251 ? -38.88749 -17.59971 35.02073  1.000 118.72297 ? 211 ASP C OD1 1 
ATOM   6290 O OD2 . ASP C 1 251 ? -37.27812 -17.54649 33.53988  1.000 120.82160 ? 211 ASP C OD2 1 
ATOM   6291 N N   . PRO C 1 252 ? -37.52670 -14.12382 33.76819  1.000 132.98343 ? 212 PRO C N   1 
ATOM   6292 C CA  . PRO C 1 252 ? -36.32752 -13.29896 33.52668  1.000 125.03817 ? 212 PRO C CA  1 
ATOM   6293 C C   . PRO C 1 252 ? -35.35501 -13.85863 32.49669  1.000 130.06586 ? 212 PRO C C   1 
ATOM   6294 O O   . PRO C 1 252 ? -34.57349 -13.08557 31.92752  1.000 125.46926 ? 212 PRO C O   1 
ATOM   6295 C CB  . PRO C 1 252 ? -35.67123 -13.21202 34.91548  1.000 118.23474 ? 212 PRO C CB  1 
ATOM   6296 C CG  . PRO C 1 252 ? -36.27295 -14.34159 35.70127  1.000 116.83401 ? 212 PRO C CG  1 
ATOM   6297 C CD  . PRO C 1 252 ? -37.67291 -14.46474 35.19186  1.000 130.20872 ? 212 PRO C CD  1 
ATOM   6298 N N   . LEU C 1 253 ? -35.35012 -15.16874 32.25606  1.000 125.41343 ? 213 LEU C N   1 
ATOM   6299 C CA  . LEU C 1 253 ? -34.36849 -15.75992 31.35272  1.000 113.45734 ? 213 LEU C CA  1 
ATOM   6300 C C   . LEU C 1 253 ? -34.72037 -15.59929 29.87621  1.000 113.68677 ? 213 LEU C C   1 
ATOM   6301 O O   . LEU C 1 253 ? -33.82747 -15.71326 29.02768  1.000 120.55080 ? 213 LEU C O   1 
ATOM   6302 C CB  . LEU C 1 253 ? -34.18777 -17.24644 31.68251  1.000 109.93204 ? 213 LEU C CB  1 
ATOM   6303 C CG  . LEU C 1 253 ? -32.99115 -17.98590 31.07722  1.000 116.48651 ? 213 LEU C CG  1 
ATOM   6304 C CD1 . LEU C 1 253 ? -31.68010 -17.30769 31.45501  1.000 92.86999  ? 213 LEU C CD1 1 
ATOM   6305 C CD2 . LEU C 1 253 ? -32.98631 -19.44692 31.50702  1.000 103.53177 ? 213 LEU C CD2 1 
ATOM   6306 N N   . PHE C 1 254 ? -35.98457 -15.32599 29.54356  1.000 112.28528 ? 214 PHE C N   1 
ATOM   6307 C CA  . PHE C 1 254 ? -36.42628 -15.35753 28.15364  1.000 116.75376 ? 214 PHE C CA  1 
ATOM   6308 C C   . PHE C 1 254 ? -37.13593 -14.06772 27.75502  1.000 115.93729 ? 214 PHE C C   1 
ATOM   6309 O O   . PHE C 1 254 ? -37.97925 -14.07534 26.85450  1.000 112.27011 ? 214 PHE C O   1 
ATOM   6310 C CB  . PHE C 1 254 ? -37.35603 -16.54756 27.91920  1.000 114.73005 ? 214 PHE C CB  1 
ATOM   6311 C CG  . PHE C 1 254 ? -36.97739 -17.77754 28.69615  1.000 112.69164 ? 214 PHE C CG  1 
ATOM   6312 C CD1 . PHE C 1 254 ? -35.95412 -18.60801 28.26979  1.000 112.67777 ? 214 PHE C CD1 1 
ATOM   6313 C CD2 . PHE C 1 254 ? -37.65417 -18.10092 29.86134  1.000 114.29232 ? 214 PHE C CD2 1 
ATOM   6314 C CE1 . PHE C 1 254 ? -35.61442 -19.73852 28.99580  1.000 112.69611 ? 214 PHE C CE1 1 
ATOM   6315 C CE2 . PHE C 1 254 ? -37.32086 -19.22590 30.58836  1.000 115.83481 ? 214 PHE C CE2 1 
ATOM   6316 C CZ  . PHE C 1 254 ? -36.30001 -20.04632 30.15595  1.000 116.05579 ? 214 PHE C CZ  1 
ATOM   6317 N N   . VAL C 1 255 ? -36.80427 -12.95176 28.39719  1.000 117.82433 ? 215 VAL C N   1 
ATOM   6318 C CA  . VAL C 1 255 ? -37.51440 -11.70052 28.13983  1.000 124.48945 ? 215 VAL C CA  1 
ATOM   6319 C C   . VAL C 1 255 ? -36.85057 -10.88288 27.03938  1.000 122.80069 ? 215 VAL C C   1 
ATOM   6320 O O   . VAL C 1 255 ? -37.53650 -10.31755 26.18412  1.000 114.41620 ? 215 VAL C O   1 
ATOM   6321 C CB  . VAL C 1 255 ? -37.65191 -10.88538 29.44041  1.000 117.99993 ? 215 VAL C CB  1 
ATOM   6322 C CG1 . VAL C 1 255 ? -38.93500 -11.26196 30.16717  1.000 121.17028 ? 215 VAL C CG1 1 
ATOM   6323 C CG2 . VAL C 1 255 ? -36.44607 -11.10353 30.33422  1.000 121.48651 ? 215 VAL C CG2 1 
ATOM   6324 N N   . HIS C 1 256 ? -35.52322 -10.80576 27.02703  1.000 125.18177 ? 216 HIS C N   1 
ATOM   6325 C CA  . HIS C 1 256 ? -34.82661 -9.96892  26.06102  1.000 120.60607 ? 216 HIS C CA  1 
ATOM   6326 C C   . HIS C 1 256 ? -34.57147 -10.68212 24.74202  1.000 115.13773 ? 216 HIS C C   1 
ATOM   6327 O O   . HIS C 1 256 ? -34.04965 -10.06435 23.80758  1.000 102.96269 ? 216 HIS C O   1 
ATOM   6328 C CB  . HIS C 1 256 ? -33.50071 -9.49755  26.65897  1.000 125.19240 ? 216 HIS C CB  1 
ATOM   6329 C CG  . HIS C 1 256 ? -33.60441 -9.10164  28.09822  1.000 130.50205 ? 216 HIS C CG  1 
ATOM   6330 N ND1 . HIS C 1 256 ? -34.43705 -8.09429  28.53603  1.000 127.23824 ? 216 HIS C ND1 1 
ATOM   6331 C CD2 . HIS C 1 256 ? -32.99863 -9.59665  29.20352  1.000 129.26103 ? 216 HIS C CD2 1 
ATOM   6332 C CE1 . HIS C 1 256 ? -34.33051 -7.97776  29.84767  1.000 127.88604 ? 216 HIS C CE1 1 
ATOM   6333 N NE2 . HIS C 1 256 ? -33.46400 -8.87756  30.27721  1.000 131.40205 ? 216 HIS C NE2 1 
ATOM   6334 N N   . ASP C 1 257 ? -34.92729 -11.95883 24.64830  1.000 115.93874 ? 217 ASP C N   1 
ATOM   6335 C CA  . ASP C 1 257 ? -34.83983 -12.72830 23.41810  1.000 101.71803 ? 217 ASP C CA  1 
ATOM   6336 C C   . ASP C 1 257 ? -36.24961 -13.10449 22.98885  1.000 87.36971  ? 217 ASP C C   1 
ATOM   6337 O O   . ASP C 1 257 ? -37.08181 -13.46708 23.82629  1.000 83.39027  ? 217 ASP C O   1 
ATOM   6338 C CB  . ASP C 1 257 ? -33.99143 -13.98906 23.60620  1.000 100.22043 ? 217 ASP C CB  1 
ATOM   6339 C CG  . ASP C 1 257 ? -32.61212 -13.68737 24.15682  1.000 111.96027 ? 217 ASP C CG  1 
ATOM   6340 O OD1 . ASP C 1 257 ? -32.51981 -12.93573 25.14892  1.000 115.02901 ? 217 ASP C OD1 1 
ATOM   6341 O OD2 . ASP C 1 257 ? -31.62055 -14.21211 23.60651  1.000 109.31941 ? 217 ASP C OD2 1 
ATOM   6342 N N   . GLU C 1 258 ? -36.52345 -13.00297 21.69096  1.000 73.94797  ? 218 GLU C N   1 
ATOM   6343 C CA  . GLU C 1 258 ? -37.81076 -13.45309 21.18085  1.000 77.56632  ? 218 GLU C CA  1 
ATOM   6344 C C   . GLU C 1 258 ? -37.99268 -14.93667 21.47893  1.000 91.60240  ? 218 GLU C C   1 
ATOM   6345 O O   . GLU C 1 258 ? -37.13104 -15.76075 21.15801  1.000 88.89883  ? 218 GLU C O   1 
ATOM   6346 C CB  . GLU C 1 258 ? -37.93592 -13.17371 19.68145  1.000 74.43584  ? 218 GLU C CB  1 
ATOM   6347 C CG  . GLU C 1 258 ? -36.80221 -13.68810 18.81527  1.000 85.45025  ? 218 GLU C CG  1 
ATOM   6348 C CD  . GLU C 1 258 ? -37.15910 -13.65966 17.34151  1.000 86.23652  ? 218 GLU C CD  1 
ATOM   6349 O OE1 . GLU C 1 258 ? -38.29636 -14.04746 16.99986  1.000 71.72280  ? 218 GLU C OE1 1 
ATOM   6350 O OE2 . GLU C 1 258 ? -36.31156 -13.23932 16.52702  1.000 90.57789  ? 218 GLU C OE2 1 
ATOM   6351 N N   . THR C 1 259 ? -39.11374 -15.27313 22.11118  1.000 90.02712  ? 219 THR C N   1 
ATOM   6352 C CA  . THR C 1 259 ? -39.35407 -16.61654 22.61660  1.000 78.19221  ? 219 THR C CA  1 
ATOM   6353 C C   . THR C 1 259 ? -40.73021 -17.06592 22.15858  1.000 83.04852  ? 219 THR C C   1 
ATOM   6354 O O   . THR C 1 259 ? -41.71862 -16.35144 22.35310  1.000 87.24711  ? 219 THR C O   1 
ATOM   6355 C CB  . THR C 1 259 ? -39.26831 -16.65929 24.14780  1.000 80.35031  ? 219 THR C CB  1 
ATOM   6356 O OG1 . THR C 1 259 ? -37.97853 -16.19893 24.57304  1.000 77.42952  ? 219 THR C OG1 1 
ATOM   6357 C CG2 . THR C 1 259 ? -39.49653 -18.07817 24.65999  1.000 76.61030  ? 219 THR C CG2 1 
ATOM   6358 N N   . HIS C 1 260 ? -40.78707 -18.24902 21.55527  1.000 86.67346  ? 220 HIS C N   1 
ATOM   6359 C CA  . HIS C 1 260 ? -42.02946 -18.84868 21.09526  1.000 71.31114  ? 220 HIS C CA  1 
ATOM   6360 C C   . HIS C 1 260 ? -42.36171 -20.05329 21.96439  1.000 82.26144  ? 220 HIS C C   1 
ATOM   6361 O O   . HIS C 1 260 ? -41.47346 -20.82999 22.33085  1.000 81.45844  ? 220 HIS C O   1 
ATOM   6362 C CB  . HIS C 1 260 ? -41.92481 -19.28056 19.62649  1.000 82.81001  ? 220 HIS C CB  1 
ATOM   6363 C CG  . HIS C 1 260 ? -41.62037 -18.16038 18.67617  1.000 96.65309  ? 220 HIS C CG  1 
ATOM   6364 N ND1 . HIS C 1 260 ? -41.01056 -16.98777 19.06916  1.000 101.52137 ? 220 HIS C ND1 1 
ATOM   6365 C CD2 . HIS C 1 260 ? -41.83622 -18.04089 17.34430  1.000 96.78067  ? 220 HIS C CD2 1 
ATOM   6366 C CE1 . HIS C 1 260 ? -40.86710 -16.19379 18.02340  1.000 96.14549  ? 220 HIS C CE1 1 
ATOM   6367 N NE2 . HIS C 1 260 ? -41.36031 -16.80904 16.96398  1.000 90.02741  ? 220 HIS C NE2 1 
ATOM   6368 N N   . VAL C 1 261 ? -43.64225 -20.20770 22.29182  1.000 85.01312  ? 221 VAL C N   1 
ATOM   6369 C CA  . VAL C 1 261 ? -44.11854 -21.31513 23.11042  1.000 81.64469  ? 221 VAL C CA  1 
ATOM   6370 C C   . VAL C 1 261 ? -45.21562 -22.04936 22.35331  1.000 78.33291  ? 221 VAL C C   1 
ATOM   6371 O O   . VAL C 1 261 ? -46.13417 -21.42126 21.81258  1.000 76.96346  ? 221 VAL C O   1 
ATOM   6372 C CB  . VAL C 1 261 ? -44.63373 -20.82956 24.47734  1.000 75.62752  ? 221 VAL C CB  1 
ATOM   6373 C CG1 . VAL C 1 261 ? -44.99121 -22.01317 25.35755  1.000 75.06297  ? 221 VAL C CG1 1 
ATOM   6374 C CG2 . VAL C 1 261 ? -43.59997 -19.94837 25.15906  1.000 72.68448  ? 221 VAL C CG2 1 
ATOM   6375 N N   . LEU C 1 262 ? -45.11919 -23.37753 22.32649  1.000 81.54835  ? 222 LEU C N   1 
ATOM   6376 C CA  . LEU C 1 262 ? -46.11047 -24.24873 21.71292  1.000 74.34386  ? 222 LEU C CA  1 
ATOM   6377 C C   . LEU C 1 262 ? -46.39865 -25.40122 22.66296  1.000 78.26430  ? 222 LEU C C   1 
ATOM   6378 O O   . LEU C 1 262 ? -45.49597 -25.90118 23.34087  1.000 74.16081  ? 222 LEU C O   1 
ATOM   6379 C CB  . LEU C 1 262 ? -45.65191 -24.78999 20.34545  1.000 67.56138  ? 222 LEU C CB  1 
ATOM   6380 C CG  . LEU C 1 262 ? -45.78624 -23.91237 19.09310  1.000 78.59957  ? 222 LEU C CG  1 
ATOM   6381 C CD1 . LEU C 1 262 ? -44.81700 -22.73897 19.08019  1.000 87.93171  ? 222 LEU C CD1 1 
ATOM   6382 C CD2 . LEU C 1 262 ? -45.61528 -24.75944 17.84248  1.000 81.42139  ? 222 LEU C CD2 1 
ATOM   6383 N N   . GLN C 1 263 ? -47.66151 -25.81002 22.71381  1.000 78.83797  ? 223 GLN C N   1 
ATOM   6384 C CA  . GLN C 1 263 ? -48.09101 -26.92146 23.54845  1.000 71.84577  ? 223 GLN C CA  1 
ATOM   6385 C C   . GLN C 1 263 ? -48.02683 -28.22287 22.76039  1.000 74.15655  ? 223 GLN C C   1 
ATOM   6386 O O   . GLN C 1 263 ? -48.44946 -28.28293 21.60216  1.000 64.01858  ? 223 GLN C O   1 
ATOM   6387 C CB  . GLN C 1 263 ? -49.51494 -26.67358 24.04765  1.000 85.74167  ? 223 GLN C CB  1 
ATOM   6388 C CG  . GLN C 1 263 ? -50.00831 -27.62178 25.12081  1.000 89.53762  ? 223 GLN C CG  1 
ATOM   6389 C CD  . GLN C 1 263 ? -51.48531 -27.42491 25.40680  1.000 90.66734  ? 223 GLN C CD  1 
ATOM   6390 O OE1 . GLN C 1 263 ? -51.97006 -27.73744 26.49191  1.000 98.63468  ? 223 GLN C OE1 1 
ATOM   6391 N NE2 . GLN C 1 263 ? -52.21118 -26.90816 24.42233  1.000 83.45586  ? 223 GLN C NE2 1 
ATOM   6392 N N   . VAL C 1 264 ? -47.49191 -29.26746 23.39591  1.000 71.32811  ? 224 VAL C N   1 
ATOM   6393 C CA  . VAL C 1 264 ? -47.32639 -30.56613 22.75833  1.000 74.48194  ? 224 VAL C CA  1 
ATOM   6394 C C   . VAL C 1 264 ? -47.80023 -31.65916 23.70705  1.000 78.91513  ? 224 VAL C C   1 
ATOM   6395 O O   . VAL C 1 264 ? -47.86003 -31.48037 24.92563  1.000 73.99504  ? 224 VAL C O   1 
ATOM   6396 C CB  . VAL C 1 264 ? -45.86408 -30.83174 22.32905  1.000 70.59496  ? 224 VAL C CB  1 
ATOM   6397 C CG1 . VAL C 1 264 ? -45.39437 -29.78686 21.32744  1.000 61.44110  ? 224 VAL C CG1 1 
ATOM   6398 C CG2 . VAL C 1 264 ? -44.95187 -30.85785 23.53869  1.000 63.35780  ? 224 VAL C CG2 1 
ATOM   6399 N N   . ASP C 1 265 ? -48.13709 -32.81054 23.12035  1.000 80.89924  ? 225 ASP C N   1 
ATOM   6400 C CA  . ASP C 1 265 ? -48.61373 -33.94708 23.90153  1.000 70.67695  ? 225 ASP C CA  1 
ATOM   6401 C C   . ASP C 1 265 ? -47.47567 -34.64551 24.63656  1.000 81.66390  ? 225 ASP C C   1 
ATOM   6402 O O   . ASP C 1 265 ? -47.61862 -35.00020 25.81192  1.000 86.36747  ? 225 ASP C O   1 
ATOM   6403 C CB  . ASP C 1 265 ? -49.34221 -34.93920 22.99388  1.000 76.85582  ? 225 ASP C CB  1 
ATOM   6404 C CG  . ASP C 1 265 ? -50.55974 -34.33358 22.32493  1.000 93.38148  ? 225 ASP C CG  1 
ATOM   6405 O OD1 . ASP C 1 265 ? -51.22120 -33.47748 22.95021  1.000 99.21024  ? 225 ASP C OD1 1 
ATOM   6406 O OD2 . ASP C 1 265 ? -50.85566 -34.71634 21.17405  1.000 91.64550  ? 225 ASP C OD2 1 
ATOM   6407 N N   . ASP C 1 266 ? -46.34261 -34.84702 23.96528  1.000 85.65866  ? 226 ASP C N   1 
ATOM   6408 C CA  . ASP C 1 266 ? -45.21518 -35.58844 24.52582  1.000 81.30841  ? 226 ASP C CA  1 
ATOM   6409 C C   . ASP C 1 266 ? -43.93495 -34.85079 24.15881  1.000 80.34401  ? 226 ASP C C   1 
ATOM   6410 O O   . ASP C 1 266 ? -43.51300 -34.87775 22.99872  1.000 79.10480  ? 226 ASP C O   1 
ATOM   6411 C CB  . ASP C 1 266 ? -45.18676 -37.02848 24.00996  1.000 67.49871  ? 226 ASP C CB  1 
ATOM   6412 C CG  . ASP C 1 266 ? -44.23505 -37.91306 24.79553  1.000 76.02542  ? 226 ASP C CG  1 
ATOM   6413 O OD1 . ASP C 1 266 ? -43.61174 -37.41689 25.75735  1.000 76.59630  ? 226 ASP C OD1 1 
ATOM   6414 O OD2 . ASP C 1 266 ? -44.11130 -39.10617 24.44875  1.000 79.94961  ? 226 ASP C OD2 1 
ATOM   6415 N N   . VAL C 1 267 ? -43.32056 -34.19335 25.14629  1.000 88.88496  ? 227 VAL C N   1 
ATOM   6416 C CA  . VAL C 1 267 ? -42.07226 -33.47543 24.90488  1.000 75.19574  ? 227 VAL C CA  1 
ATOM   6417 C C   . VAL C 1 267 ? -40.94480 -34.44476 24.57542  1.000 72.45990  ? 227 VAL C C   1 
ATOM   6418 O O   . VAL C 1 267 ? -40.04195 -34.11861 23.79335  1.000 67.67690  ? 227 VAL C O   1 
ATOM   6419 C CB  . VAL C 1 267 ? -41.73426 -32.60864 26.13525  1.000 75.71604  ? 227 VAL C CB  1 
ATOM   6420 C CG1 . VAL C 1 267 ? -40.23817 -32.35528 26.24110  1.000 81.32529  ? 227 VAL C CG1 1 
ATOM   6421 C CG2 . VAL C 1 267 ? -42.49092 -31.29453 26.08433  1.000 71.80899  ? 227 VAL C CG2 1 
ATOM   6422 N N   . LYS C 1 268 ? -41.00250 -35.66183 25.12068  1.000 73.78042  ? 228 LYS C N   1 
ATOM   6423 C CA  . LYS C 1 268 ? -39.96306 -36.65442 24.86598  1.000 71.31917  ? 228 LYS C CA  1 
ATOM   6424 C C   . LYS C 1 268 ? -39.89442 -37.05316 23.39576  1.000 64.77833  ? 228 LYS C C   1 
ATOM   6425 O O   . LYS C 1 268 ? -38.82728 -37.44480 22.91046  1.000 60.41941  ? 228 LYS C O   1 
ATOM   6426 C CB  . LYS C 1 268 ? -40.19329 -37.87889 25.75319  1.000 68.34908  ? 228 LYS C CB  1 
ATOM   6427 C CG  . LYS C 1 268 ? -39.99147 -37.58682 27.23296  1.000 77.55950  ? 228 LYS C CG  1 
ATOM   6428 C CD  . LYS C 1 268 ? -40.48488 -38.71730 28.12320  1.000 74.50196  ? 228 LYS C CD  1 
ATOM   6429 C CE  . LYS C 1 268 ? -41.99930 -38.69765 28.27217  1.000 79.50951  ? 228 LYS C CE  1 
ATOM   6430 N NZ  . LYS C 1 268 ? -42.69102 -39.54460 27.26168  1.000 93.60726  ? 228 LYS C NZ  1 
ATOM   6431 N N   . GLN C 1 269 ? -41.00919 -36.95774 22.66973  1.000 65.61335  ? 229 GLN C N   1 
ATOM   6432 C CA  . GLN C 1 269 ? -41.01563 -37.32137 21.25729  1.000 62.17256  ? 229 GLN C CA  1 
ATOM   6433 C C   . GLN C 1 269 ? -40.19693 -36.37031 20.38975  1.000 62.08423  ? 229 GLN C C   1 
ATOM   6434 O O   . GLN C 1 269 ? -39.94920 -36.68477 19.21994  1.000 62.89658  ? 229 GLN C O   1 
ATOM   6435 C CB  . GLN C 1 269 ? -42.45855 -37.36723 20.74696  1.000 58.86469  ? 229 GLN C CB  1 
ATOM   6436 C CG  . GLN C 1 269 ? -42.71893 -38.41243 19.68141  1.000 68.00996  ? 229 GLN C CG  1 
ATOM   6437 C CD  . GLN C 1 269 ? -42.48655 -39.81704 20.18947  1.000 78.42867  ? 229 GLN C CD  1 
ATOM   6438 O OE1 . GLN C 1 269 ? -42.65393 -40.09453 21.37695  1.000 68.74291  ? 229 GLN C OE1 1 
ATOM   6439 N NE2 . GLN C 1 269 ? -42.10475 -40.71543 19.29139  1.000 82.68098  ? 229 GLN C NE2 1 
ATOM   6440 N N   . LEU C 1 270 ? -39.79206 -35.21546 20.91910  1.000 59.25376  ? 230 LEU C N   1 
ATOM   6441 C CA  . LEU C 1 270 ? -39.07005 -34.21404 20.14736  1.000 60.67687  ? 230 LEU C CA  1 
ATOM   6442 C C   . LEU C 1 270 ? -37.59325 -34.11885 20.50019  1.000 58.21123  ? 230 LEU C C   1 
ATOM   6443 O O   . LEU C 1 270 ? -36.86878 -33.35388 19.85330  1.000 55.57830  ? 230 LEU C O   1 
ATOM   6444 C CB  . LEU C 1 270 ? -39.70823 -32.82587 20.32961  1.000 50.74926  ? 230 LEU C CB  1 
ATOM   6445 C CG  . LEU C 1 270 ? -41.10805 -32.50834 19.78089  1.000 62.93255  ? 230 LEU C CG  1 
ATOM   6446 C CD1 . LEU C 1 270 ? -42.21896 -33.32082 20.44015  1.000 57.09430  ? 230 LEU C CD1 1 
ATOM   6447 C CD2 . LEU C 1 270 ? -41.38491 -31.02475 19.92723  1.000 66.96762  ? 230 LEU C CD2 1 
ATOM   6448 N N   . ILE C 1 271 ? -37.12966 -34.86363 21.49616  1.000 60.56893  ? 231 ILE C N   1 
ATOM   6449 C CA  . ILE C 1 271 ? -35.80200 -34.64630 22.05728  1.000 60.78744  ? 231 ILE C CA  1 
ATOM   6450 C C   . ILE C 1 271 ? -34.75027 -35.30548 21.17417  1.000 61.75557  ? 231 ILE C C   1 
ATOM   6451 O O   . ILE C 1 271 ? -34.84899 -36.49362 20.84153  1.000 54.06794  ? 231 ILE C O   1 
ATOM   6452 C CB  . ILE C 1 271 ? -35.73224 -35.17529 23.49749  1.000 57.74274  ? 231 ILE C CB  1 
ATOM   6453 C CG1 . ILE C 1 271 ? -36.63368 -34.34493 24.41294  1.000 61.14157  ? 231 ILE C CG1 1 
ATOM   6454 C CG2 . ILE C 1 271 ? -34.30327 -35.15664 23.99831  1.000 52.34487  ? 231 ILE C CG2 1 
ATOM   6455 C CD1 . ILE C 1 271 ? -36.78191 -34.91800 25.80501  1.000 59.69220  ? 231 ILE C CD1 1 
ATOM   6456 N N   . ASP C 1 272 ? -33.73511 -34.52785 20.79932  1.000 55.71480  ? 232 ASP C N   1 
ATOM   6457 C CA  . ASP C 1 272 ? -32.52871 -35.03663 20.15941  1.000 52.37924  ? 232 ASP C CA  1 
ATOM   6458 C C   . ASP C 1 272 ? -31.34793 -34.20836 20.64244  1.000 56.64272  ? 232 ASP C C   1 
ATOM   6459 O O   . ASP C 1 272 ? -31.40859 -32.97511 20.63680  1.000 56.89274  ? 232 ASP C O   1 
ATOM   6460 C CB  . ASP C 1 272 ? -32.63009 -34.97919 18.63183  1.000 51.11564  ? 232 ASP C CB  1 
ATOM   6461 C CG  . ASP C 1 272 ? -31.28956 -35.18811 17.95368  1.000 61.27092  ? 232 ASP C CG  1 
ATOM   6462 O OD1 . ASP C 1 272 ? -30.80931 -36.33988 17.91767  1.000 61.84153  ? 232 ASP C OD1 1 
ATOM   6463 O OD2 . ASP C 1 272 ? -30.71186 -34.19640 17.46306  1.000 64.13507  ? 232 ASP C OD2 1 
ATOM   6464 N N   . ARG C 1 273 ? -30.28247 -34.88478 21.06100  1.000 60.22401  ? 233 ARG C N   1 
ATOM   6465 C CA  . ARG C 1 273 ? -29.13363 -34.21726 21.65368  1.000 59.66611  ? 233 ARG C CA  1 
ATOM   6466 C C   . ARG C 1 273 ? -28.06995 -33.83955 20.62998  1.000 54.96771  ? 233 ARG C C   1 
ATOM   6467 O O   . ARG C 1 273 ? -26.96177 -33.45987 21.01947  1.000 49.36611  ? 233 ARG C O   1 
ATOM   6468 C CB  . ARG C 1 273 ? -28.53218 -35.09430 22.75395  1.000 54.47748  ? 233 ARG C CB  1 
ATOM   6469 C CG  . ARG C 1 273 ? -29.46850 -35.27257 23.93854  1.000 53.10760  ? 233 ARG C CG  1 
ATOM   6470 C CD  . ARG C 1 273 ? -29.10468 -36.47603 24.78464  1.000 47.16256  ? 233 ARG C CD  1 
ATOM   6471 N NE  . ARG C 1 273 ? -30.17045 -36.79322 25.72756  1.000 72.90950  ? 233 ARG C NE  1 
ATOM   6472 C CZ  . ARG C 1 273 ? -31.25860 -37.48781 25.42344  1.000 79.79584  ? 233 ARG C CZ  1 
ATOM   6473 N NH1 . ARG C 1 273 ? -31.45682 -37.96311 24.20543  1.000 63.09886  ? 233 ARG C NH1 1 
ATOM   6474 N NH2 . ARG C 1 273 ? -32.17201 -37.70866 26.36494  1.000 63.25716  ? 233 ARG C NH2 1 
ATOM   6475 N N   . GLY C 1 274 ? -28.37444 -33.93539 19.33821  1.000 55.59747  ? 234 GLY C N   1 
ATOM   6476 C CA  . GLY C 1 274 ? -27.49910 -33.36225 18.34066  1.000 46.43132  ? 234 GLY C CA  1 
ATOM   6477 C C   . GLY C 1 274 ? -27.62165 -31.85239 18.30234  1.000 55.92893  ? 234 GLY C C   1 
ATOM   6478 O O   . GLY C 1 274 ? -28.62975 -31.27240 18.70540  1.000 62.94072  ? 234 GLY C O   1 
ATOM   6479 N N   . ILE C 1 275 ? -26.56691 -31.19615 17.81608  1.000 52.78072  ? 235 ILE C N   1 
ATOM   6480 C CA  . ILE C 1 275 ? -26.53421 -29.74030 17.74908  1.000 49.16186  ? 235 ILE C CA  1 
ATOM   6481 C C   . ILE C 1 275 ? -25.57854 -29.32062 16.64168  1.000 43.34818  ? 235 ILE C C   1 
ATOM   6482 O O   . ILE C 1 275 ? -24.75510 -30.10744 16.17060  1.000 52.29410  ? 235 ILE C O   1 
ATOM   6483 C CB  . ILE C 1 275 ? -26.11710 -29.12432 19.10774  1.000 55.05052  ? 235 ILE C CB  1 
ATOM   6484 C CG1 . ILE C 1 275 ? -26.53085 -27.65395 19.19891  1.000 45.71151  ? 235 ILE C CG1 1 
ATOM   6485 C CG2 . ILE C 1 275 ? -24.62242 -29.26890 19.31610  1.000 49.98899  ? 235 ILE C CG2 1 
ATOM   6486 C CD1 . ILE C 1 275 ? -26.41638 -27.07778 20.58842  1.000 53.07852  ? 235 ILE C CD1 1 
ATOM   6487 N N   . ALA C 1 276 ? -25.70188 -28.06428 16.21897  1.000 50.81668  ? 236 ALA C N   1 
ATOM   6488 C CA  . ALA C 1 276 ? -24.82039 -27.46703 15.22975  1.000 51.29108  ? 236 ALA C CA  1 
ATOM   6489 C C   . ALA C 1 276 ? -24.20282 -26.19572 15.79476  1.000 55.67969  ? 236 ALA C C   1 
ATOM   6490 O O   . ALA C 1 276 ? -24.82550 -25.48493 16.58906  1.000 56.48914  ? 236 ALA C O   1 
ATOM   6491 C CB  . ALA C 1 276 ? -25.56735 -27.14863 13.92941  1.000 36.66603  ? 236 ALA C CB  1 
ATOM   6492 N N   . VAL C 1 277 ? -22.96470 -25.92283 15.38687  1.000 55.39267  ? 237 VAL C N   1 
ATOM   6493 C CA  . VAL C 1 277 ? -22.27192 -24.68180 15.71728  1.000 52.90139  ? 237 VAL C CA  1 
ATOM   6494 C C   . VAL C 1 277 ? -21.63688 -24.14726 14.44064  1.000 47.17170  ? 237 VAL C C   1 
ATOM   6495 O O   . VAL C 1 277 ? -20.87869 -24.86248 13.77511  1.000 51.88483  ? 237 VAL C O   1 
ATOM   6496 C CB  . VAL C 1 277 ? -21.20752 -24.88189 16.81089  1.000 47.30961  ? 237 VAL C CB  1 
ATOM   6497 C CG1 . VAL C 1 277 ? -20.44050 -23.59434 17.04376  1.000 46.90801  ? 237 VAL C CG1 1 
ATOM   6498 C CG2 . VAL C 1 277 ? -21.84731 -25.35864 18.10649  1.000 48.42367  ? 237 VAL C CG2 1 
ATOM   6499 N N   . ARG C 1 278 ? -21.94567 -22.89793 14.09998  1.000 43.03629  ? 238 ARG C N   1 
ATOM   6500 C CA  . ARG C 1 278 ? -21.38577 -22.22439 12.93355  1.000 50.24362  ? 238 ARG C CA  1 
ATOM   6501 C C   . ARG C 1 278 ? -20.71650 -20.93351 13.37924  1.000 58.80786  ? 238 ARG C C   1 
ATOM   6502 O O   . ARG C 1 278 ? -21.36179 -20.07440 13.98955  1.000 49.20825  ? 238 ARG C O   1 
ATOM   6503 C CB  . ARG C 1 278 ? -22.45792 -21.91769 11.88493  1.000 44.58138  ? 238 ARG C CB  1 
ATOM   6504 C CG  . ARG C 1 278 ? -21.88670 -21.29067 10.61016  1.000 68.34686  ? 238 ARG C CG  1 
ATOM   6505 C CD  . ARG C 1 278 ? -22.92898 -21.08764 9.51470   1.000 84.41895  ? 238 ARG C CD  1 
ATOM   6506 N NE  . ARG C 1 278 ? -22.34275 -20.48427 8.32133   1.000 87.10967  ? 238 ARG C NE  1 
ATOM   6507 C CZ  . ARG C 1 278 ? -21.87683 -21.16504 7.28360   1.000 85.27577  ? 238 ARG C CZ  1 
ATOM   6508 N NH1 . ARG C 1 278 ? -21.90576 -22.48553 7.25607   1.000 84.97564  ? 238 ARG C NH1 1 
ATOM   6509 N NH2 . ARG C 1 278 ? -21.36341 -20.50371 6.24977   1.000 74.77821  ? 238 ARG C NH2 1 
ATOM   6510 N N   . MET C 1 279 ? -19.42822 -20.79942 13.07493  1.000 51.73053  ? 239 MET C N   1 
ATOM   6511 C CA  . MET C 1 279 ? -18.65732 -19.61001 13.40512  1.000 48.05681  ? 239 MET C CA  1 
ATOM   6512 C C   . MET C 1 279 ? -18.19682 -18.94467 12.11905  1.000 50.84905  ? 239 MET C C   1 
ATOM   6513 O O   . MET C 1 279 ? -17.66096 -19.60971 11.22564  1.000 55.87070  ? 239 MET C O   1 
ATOM   6514 C CB  . MET C 1 279 ? -17.45116 -19.94274 14.28366  1.000 50.43143  ? 239 MET C CB  1 
ATOM   6515 C CG  . MET C 1 279 ? -17.68978 -19.72771 15.76642  1.000 63.72474  ? 239 MET C CG  1 
ATOM   6516 S SD  . MET C 1 279 ? -16.35017 -20.36504 16.79540  1.000 65.48514  ? 239 MET C SD  1 
ATOM   6517 C CE  . MET C 1 279 ? -16.49978 -22.12608 16.50853  1.000 68.08952  ? 239 MET C CE  1 
ATOM   6518 N N   . GLU C 1 280 ? -18.41869 -17.63922 12.02614  1.000 50.56742  ? 240 GLU C N   1 
ATOM   6519 C CA  . GLU C 1 280 ? -17.97510 -16.84092 10.89605  1.000 44.22677  ? 240 GLU C CA  1 
ATOM   6520 C C   . GLU C 1 280 ? -17.13968 -15.68382 11.41421  1.000 54.50819  ? 240 GLU C C   1 
ATOM   6521 O O   . GLU C 1 280 ? -17.45619 -15.09433 12.45236  1.000 46.07260  ? 240 GLU C O   1 
ATOM   6522 C CB  . GLU C 1 280 ? -19.14860 -16.28944 10.07333  1.000 49.60834  ? 240 GLU C CB  1 
ATOM   6523 C CG  . GLU C 1 280 ? -20.18898 -17.30690 9.66186   1.000 72.93471  ? 240 GLU C CG  1 
ATOM   6524 C CD  . GLU C 1 280 ? -21.43742 -16.64372 9.12152   1.000 78.13686  ? 240 GLU C CD  1 
ATOM   6525 O OE1 . GLU C 1 280 ? -21.42160 -15.40700 8.94118   1.000 70.89334  ? 240 GLU C OE1 1 
ATOM   6526 O OE2 . GLU C 1 280 ? -22.42940 -17.35445 8.86865   1.000 85.62083  ? 240 GLU C OE2 1 
ATOM   6527 N N   . ARG C 1 281 ? -16.06445 -15.37281 10.69773  1.000 45.70526  ? 241 ARG C N   1 
ATOM   6528 C CA  . ARG C 1 281 ? -15.32302 -14.14616 10.94041  1.000 45.78395  ? 241 ARG C CA  1 
ATOM   6529 C C   . ARG C 1 281 ? -14.95855 -13.51956 9.60670   1.000 48.20636  ? 241 ARG C C   1 
ATOM   6530 O O   . ARG C 1 281 ? -14.43895 -14.20038 8.71671   1.000 51.70541  ? 241 ARG C O   1 
ATOM   6531 C CB  . ARG C 1 281 ? -14.05404 -14.39246 11.76781  1.000 55.31373  ? 241 ARG C CB  1 
ATOM   6532 C CG  . ARG C 1 281 ? -13.24673 -13.11731 12.02172  1.000 48.32925  ? 241 ARG C CG  1 
ATOM   6533 C CD  . ARG C 1 281 ? -12.13215 -13.32756 13.03758  1.000 49.59650  ? 241 ARG C CD  1 
ATOM   6534 N NE  . ARG C 1 281 ? -11.50679 -12.07197 13.44060  1.000 58.33050  ? 241 ARG C NE  1 
ATOM   6535 C CZ  . ARG C 1 281 ? -12.00740 -11.23531 14.34089  1.000 58.25721  ? 241 ARG C CZ  1 
ATOM   6536 N NH1 . ARG C 1 281 ? -13.14686 -11.48889 14.96351  1.000 46.79290  ? 241 ARG C NH1 1 
ATOM   6537 N NH2 . ARG C 1 281 ? -11.34699 -10.11581 14.62505  1.000 52.59692  ? 241 ARG C NH2 1 
ATOM   6538 N N   . LYS C 1 282 ? -15.23741 -12.22488 9.47938   1.000 38.58101  ? 242 LYS C N   1 
ATOM   6539 C CA  . LYS C 1 282 ? -14.76485 -11.40303 8.37358   1.000 46.43469  ? 242 LYS C CA  1 
ATOM   6540 C C   . LYS C 1 282 ? -13.84482 -10.35218 8.97084   1.000 48.93285  ? 242 LYS C C   1 
ATOM   6541 O O   . LYS C 1 282 ? -14.28026 -9.54576  9.79911   1.000 48.45954  ? 242 LYS C O   1 
ATOM   6542 C CB  . LYS C 1 282 ? -15.93014 -10.74976 7.62596   1.000 39.92816  ? 242 LYS C CB  1 
ATOM   6543 C CG  . LYS C 1 282 ? -15.50820 -9.90044  6.43443   1.000 44.84885  ? 242 LYS C CG  1 
ATOM   6544 C CD  . LYS C 1 282 ? -16.71634 -9.37262  5.67806   1.000 43.52486  ? 242 LYS C CD  1 
ATOM   6545 C CE  . LYS C 1 282 ? -17.52267 -8.41143  6.53375   1.000 43.41949  ? 242 LYS C CE  1 
ATOM   6546 N NZ  . LYS C 1 282 ? -16.70195 -7.24611  6.96067   1.000 44.53733  ? 242 LYS C NZ  1 
ATOM   6547 N N   . GLY C 1 283 ? -12.58149 -10.35488 8.55555   1.000 46.83100  ? 243 GLY C N   1 
ATOM   6548 C CA  . GLY C 1 283 ? -11.61591 -9.53102  9.24393   1.000 41.95352  ? 243 GLY C CA  1 
ATOM   6549 C C   . GLY C 1 283 ? -10.45398 -9.10227  8.38008   1.000 49.58045  ? 243 GLY C C   1 
ATOM   6550 O O   . GLY C 1 283 ? -10.39982 -9.36543  7.17638   1.000 44.90081  ? 243 GLY C O   1 
ATOM   6551 N N   . VAL C 1 284 ? -9.51517  -8.42545  9.03557   1.000 49.09482  ? 244 VAL C N   1 
ATOM   6552 C CA  . VAL C 1 284 ? -8.35372  -7.81922  8.39793   1.000 44.79351  ? 244 VAL C CA  1 
ATOM   6553 C C   . VAL C 1 284 ? -7.11587  -8.58854  8.83304   1.000 45.78015  ? 244 VAL C C   1 
ATOM   6554 O O   . VAL C 1 284 ? -6.81566  -8.66603  10.03022  1.000 54.40927  ? 244 VAL C O   1 
ATOM   6555 C CB  . VAL C 1 284 ? -8.22456  -6.33277  8.76428   1.000 53.87199  ? 244 VAL C CB  1 
ATOM   6556 C CG1 . VAL C 1 284 ? -7.03742  -5.70942  8.04993   1.000 51.72668  ? 244 VAL C CG1 1 
ATOM   6557 C CG2 . VAL C 1 284 ? -9.51701  -5.59219  8.43263   1.000 44.42667  ? 244 VAL C CG2 1 
ATOM   6558 N N   . SER C 1 285 ? -6.39264  -9.14911  7.86909   1.000 49.89826  ? 245 SER C N   1 
ATOM   6559 C CA  . SER C 1 285 ? -5.10855  -9.78949  8.12732   1.000 50.21117  ? 245 SER C CA  1 
ATOM   6560 C C   . SER C 1 285 ? -4.01903  -8.77916  7.79449   1.000 40.44670  ? 245 SER C C   1 
ATOM   6561 O O   . SER C 1 285 ? -3.75502  -8.50099  6.61967   1.000 49.75989  ? 245 SER C O   1 
ATOM   6562 C CB  . SER C 1 285 ? -4.95103  -11.06679 7.30805   1.000 50.58838  ? 245 SER C CB  1 
ATOM   6563 O OG  . SER C 1 285 ? -5.89578  -12.04475 7.69482   1.000 50.21703  ? 245 SER C OG  1 
ATOM   6564 N N   . GLY C 1 286 ? -3.38638  -8.23497  8.82790   1.000 47.37734  ? 246 GLY C N   1 
ATOM   6565 C CA  . GLY C 1 286 ? -2.41232  -7.18318  8.62674   1.000 40.84667  ? 246 GLY C CA  1 
ATOM   6566 C C   . GLY C 1 286 ? -3.11091  -5.87534  8.32477   1.000 48.55241  ? 246 GLY C C   1 
ATOM   6567 O O   . GLY C 1 286 ? -3.57994  -5.18163  9.23179   1.000 53.08391  ? 246 GLY C O   1 
ATOM   6568 N N   . GLN C 1 287 ? -3.18440  -5.53385  7.03912   1.000 53.89455  ? 247 GLN C N   1 
ATOM   6569 C CA  . GLN C 1 287 ? -3.94256  -4.38269  6.57462   1.000 56.65362  ? 247 GLN C CA  1 
ATOM   6570 C C   . GLN C 1 287 ? -4.89446  -4.74723  5.44516   1.000 50.57661  ? 247 GLN C C   1 
ATOM   6571 O O   . GLN C 1 287 ? -5.55458  -3.85576  4.89982   1.000 55.31452  ? 247 GLN C O   1 
ATOM   6572 C CB  . GLN C 1 287 ? -2.99933  -3.25749  6.11469   1.000 55.32939  ? 247 GLN C CB  1 
ATOM   6573 C CG  . GLN C 1 287 ? -2.53990  -2.34133  7.23830   1.000 51.75940  ? 247 GLN C CG  1 
ATOM   6574 C CD  . GLN C 1 287 ? -1.31948  -1.52119  6.87948   1.000 55.56700  ? 247 GLN C CD  1 
ATOM   6575 O OE1 . GLN C 1 287 ? -0.97849  -1.37145  5.70758   1.000 51.58076  ? 247 GLN C OE1 1 
ATOM   6576 N NE2 . GLN C 1 287 ? -0.64766  -0.99200  7.89306   1.000 50.60987  ? 247 GLN C NE2 1 
ATOM   6577 N N   . THR C 1 288 ? -4.99075  -6.02917  5.09246   1.000 50.12808  ? 248 THR C N   1 
ATOM   6578 C CA  . THR C 1 288 ? -5.81810  -6.49640  3.98607   1.000 46.60160  ? 248 THR C CA  1 
ATOM   6579 C C   . THR C 1 288 ? -7.21990  -6.82626  4.48655   1.000 48.05906  ? 248 THR C C   1 
ATOM   6580 O O   . THR C 1 288 ? -7.38706  -7.68287  5.36126   1.000 49.98977  ? 248 THR C O   1 
ATOM   6581 C CB  . THR C 1 288 ? -5.18434  -7.72108  3.32653   1.000 49.21952  ? 248 THR C CB  1 
ATOM   6582 O OG1 . THR C 1 288 ? -3.84609  -7.40385  2.91880   1.000 55.53913  ? 248 THR C OG1 1 
ATOM   6583 C CG2 . THR C 1 288 ? -5.99728  -8.16494  2.10996   1.000 38.24922  ? 248 THR C CG2 1 
ATOM   6584 N N   . GLN C 1 289 ? -8.22081  -6.15240  3.92730   1.000 49.79596  ? 249 GLN C N   1 
ATOM   6585 C CA  . GLN C 1 289 ? -9.59971  -6.33838  4.34608   1.000 49.19022  ? 249 GLN C CA  1 
ATOM   6586 C C   . GLN C 1 289 ? -10.16964 -7.64449  3.79092   1.000 51.74004  ? 249 GLN C C   1 
ATOM   6587 O O   . GLN C 1 289 ? -9.57567  -8.30626  2.93497   1.000 45.85257  ? 249 GLN C O   1 
ATOM   6588 C CB  . GLN C 1 289 ? -10.46203 -5.16253  3.88133   1.000 50.71372  ? 249 GLN C CB  1 
ATOM   6589 C CG  . GLN C 1 289 ? -9.81736  -3.79048  4.03319   1.000 53.88910  ? 249 GLN C CG  1 
ATOM   6590 C CD  . GLN C 1 289 ? -9.69145  -3.36997  5.48289   1.000 57.04670  ? 249 GLN C CD  1 
ATOM   6591 O OE1 . GLN C 1 289 ? -10.68782 -3.06426  6.13881   1.000 48.76565  ? 249 GLN C OE1 1 
ATOM   6592 N NE2 . GLN C 1 289 ? -8.46514  -3.34911  5.99103   1.000 40.48632  ? 249 GLN C NE2 1 
ATOM   6593 N N   . ASN C 1 290 ? -11.34583 -8.01240  4.30632   1.000 46.27394  ? 250 ASN C N   1 
ATOM   6594 C CA  . ASN C 1 290 ? -12.21134 -9.02827  3.69972   1.000 48.40779  ? 250 ASN C CA  1 
ATOM   6595 C C   . ASN C 1 290 ? -11.58383 -10.42373 3.72623   1.000 53.86319  ? 250 ASN C C   1 
ATOM   6596 O O   . ASN C 1 290 ? -11.70449 -11.18899 2.76824   1.000 61.41655  ? 250 ASN C O   1 
ATOM   6597 C CB  . ASN C 1 290 ? -12.60044 -8.64093  2.26946   1.000 40.75980  ? 250 ASN C CB  1 
ATOM   6598 C CG  . ASN C 1 290 ? -13.83533 -9.37816  1.78024   1.000 47.63546  ? 250 ASN C CG  1 
ATOM   6599 O OD1 . ASN C 1 290 ? -14.79633 -9.56580  2.52670   1.000 53.85025  ? 250 ASN C OD1 1 
ATOM   6600 N ND2 . ASN C 1 290 ? -13.80953 -9.80954  0.52351   1.000 41.69784  ? 250 ASN C ND2 1 
ATOM   6601 N N   . GLN C 1 291 ? -10.90439 -10.76105 4.81829   1.000 50.24839  ? 251 GLN C N   1 
ATOM   6602 C CA  . GLN C 1 291 ? -10.46962 -12.13530 5.02530   1.000 47.59179  ? 251 GLN C CA  1 
ATOM   6603 C C   . GLN C 1 291 ? -11.61133 -12.93453 5.64362   1.000 49.06314  ? 251 GLN C C   1 
ATOM   6604 O O   . GLN C 1 291 ? -12.18158 -12.53337 6.66285   1.000 43.66289  ? 251 GLN C O   1 
ATOM   6605 C CB  . GLN C 1 291 ? -9.22418  -12.17656 5.90706   1.000 45.72472  ? 251 GLN C CB  1 
ATOM   6606 C CG  . GLN C 1 291 ? -8.07516  -11.34019 5.35907   1.000 48.37502  ? 251 GLN C CG  1 
ATOM   6607 C CD  . GLN C 1 291 ? -7.45234  -11.94243 4.11007   1.000 56.84454  ? 251 GLN C CD  1 
ATOM   6608 O OE1 . GLN C 1 291 ? -7.95856  -11.76570 3.00083   1.000 60.42731  ? 251 GLN C OE1 1 
ATOM   6609 N NE2 . GLN C 1 291 ? -6.34347  -12.64966 4.28467   1.000 52.15888  ? 251 GLN C NE2 1 
ATOM   6610 N N   . LEU C 1 292 ? -11.93814 -14.06963 5.03261   1.000 48.17067  ? 252 LEU C N   1 
ATOM   6611 C CA  . LEU C 1 292 ? -13.16871 -14.79311 5.32415   1.000 43.58442  ? 252 LEU C CA  1 
ATOM   6612 C C   . LEU C 1 292 ? -12.85033 -16.15592 5.91888   1.000 47.16444  ? 252 LEU C C   1 
ATOM   6613 O O   . LEU C 1 292 ? -12.04298 -16.90769 5.36419   1.000 39.79532  ? 252 LEU C O   1 
ATOM   6614 C CB  . LEU C 1 292 ? -14.00949 -14.95036 4.05787   1.000 36.95408  ? 252 LEU C CB  1 
ATOM   6615 C CG  . LEU C 1 292 ? -14.30210 -13.63687 3.32883   1.000 39.30227  ? 252 LEU C CG  1 
ATOM   6616 C CD1 . LEU C 1 292 ? -15.10921 -13.88155 2.06526   1.000 39.46640  ? 252 LEU C CD1 1 
ATOM   6617 C CD2 . LEU C 1 292 ? -15.02807 -12.67444 4.25169   1.000 32.91035  ? 252 LEU C CD2 1 
ATOM   6618 N N   . PHE C 1 293 ? -13.48223 -16.46696 7.04798   1.000 47.25206  ? 253 PHE C N   1 
ATOM   6619 C CA  . PHE C 1 293 ? -13.25672 -17.71851 7.75668   1.000 49.26037  ? 253 PHE C CA  1 
ATOM   6620 C C   . PHE C 1 293 ? -14.59979 -18.29246 8.17760   1.000 51.67862  ? 253 PHE C C   1 
ATOM   6621 O O   . PHE C 1 293 ? -15.45256 -17.56351 8.69457   1.000 57.05619  ? 253 PHE C O   1 
ATOM   6622 C CB  . PHE C 1 293 ? -12.36642 -17.50769 8.98666   1.000 45.34273  ? 253 PHE C CB  1 
ATOM   6623 C CG  . PHE C 1 293 ? -11.14397 -16.67640 8.71687   1.000 55.08569  ? 253 PHE C CG  1 
ATOM   6624 C CD1 . PHE C 1 293 ? -11.21167 -15.29142 8.73157   1.000 46.34831  ? 253 PHE C CD1 1 
ATOM   6625 C CD2 . PHE C 1 293 ? -9.92642  -17.28003 8.44216   1.000 54.23858  ? 253 PHE C CD2 1 
ATOM   6626 C CE1 . PHE C 1 293 ? -10.08832 -14.52315 8.47874   1.000 58.74669  ? 253 PHE C CE1 1 
ATOM   6627 C CE2 . PHE C 1 293 ? -8.79942  -16.51839 8.19038   1.000 53.72079  ? 253 PHE C CE2 1 
ATOM   6628 C CZ  . PHE C 1 293 ? -8.88020  -15.13877 8.20882   1.000 61.80013  ? 253 PHE C CZ  1 
ATOM   6629 N N   . THR C 1 294 ? -14.78318 -19.59405 7.96672   1.000 46.74192  ? 254 THR C N   1 
ATOM   6630 C CA  . THR C 1 294 ? -16.01212 -20.26910 8.35909   1.000 47.49638  ? 254 THR C CA  1 
ATOM   6631 C C   . THR C 1 294 ? -15.68034 -21.60982 8.99311   1.000 48.47650  ? 254 THR C C   1 
ATOM   6632 O O   . THR C 1 294 ? -14.90323 -22.39055 8.43545   1.000 53.03411  ? 254 THR C O   1 
ATOM   6633 C CB  . THR C 1 294 ? -16.94230 -20.47276 7.15636   1.000 43.34126  ? 254 THR C CB  1 
ATOM   6634 O OG1 . THR C 1 294 ? -17.12804 -19.22469 6.47878   1.000 59.23980  ? 254 THR C OG1 1 
ATOM   6635 C CG2 . THR C 1 294 ? -18.29204 -20.99049 7.61139   1.000 61.02273  ? 254 THR C CG2 1 
ATOM   6636 N N   . TYR C 1 295 ? -16.27679 -21.87114 10.15361  1.000 43.71065  ? 255 TYR C N   1 
ATOM   6637 C CA  . TYR C 1 295 ? -16.15931 -23.15377 10.83133  1.000 47.70174  ? 255 TYR C CA  1 
ATOM   6638 C C   . TYR C 1 295 ? -17.55236 -23.63664 11.19296  1.000 49.96329  ? 255 TYR C C   1 
ATOM   6639 O O   . TYR C 1 295 ? -18.35720 -22.87328 11.73706  1.000 55.72109  ? 255 TYR C O   1 
ATOM   6640 C CB  . TYR C 1 295 ? -15.29256 -23.07288 12.09403  1.000 39.70918  ? 255 TYR C CB  1 
ATOM   6641 C CG  . TYR C 1 295 ? -15.29471 -24.36854 12.88084  1.000 52.47369  ? 255 TYR C CG  1 
ATOM   6642 C CD1 . TYR C 1 295 ? -14.50786 -25.44417 12.49186  1.000 54.46537  ? 255 TYR C CD1 1 
ATOM   6643 C CD2 . TYR C 1 295 ? -16.10429 -24.52299 13.99995  1.000 50.60363  ? 255 TYR C CD2 1 
ATOM   6644 C CE1 . TYR C 1 295 ? -14.51897 -26.63152 13.20169  1.000 48.98434  ? 255 TYR C CE1 1 
ATOM   6645 C CE2 . TYR C 1 295 ? -16.12153 -25.70419 14.71491  1.000 49.02922  ? 255 TYR C CE2 1 
ATOM   6646 C CZ  . TYR C 1 295 ? -15.32704 -26.75567 14.31180  1.000 54.87803  ? 255 TYR C CZ  1 
ATOM   6647 O OH  . TYR C 1 295 ? -15.33983 -27.93636 15.01930  1.000 55.46505  ? 255 TYR C OH  1 
ATOM   6648 N N   . GLU C 1 296 ? -17.82816 -24.90217 10.89779  1.000 48.70146  ? 256 GLU C N   1 
ATOM   6649 C CA  . GLU C 1 296 ? -19.14844 -25.47085 11.10235  1.000 54.17345  ? 256 GLU C CA  1 
ATOM   6650 C C   . GLU C 1 296 ? -18.98075 -26.90643 11.56886  1.000 51.64027  ? 256 GLU C C   1 
ATOM   6651 O O   . GLU C 1 296 ? -18.12245 -27.63425 11.06160  1.000 49.56684  ? 256 GLU C O   1 
ATOM   6652 C CB  . GLU C 1 296 ? -19.97597 -25.40549 9.81668   1.000 47.19078  ? 256 GLU C CB  1 
ATOM   6653 C CG  . GLU C 1 296 ? -21.45968 -25.64841 9.99880   1.000 69.96006  ? 256 GLU C CG  1 
ATOM   6654 C CD  . GLU C 1 296 ? -22.24594 -25.22159 8.77995   1.000 88.39208  ? 256 GLU C CD  1 
ATOM   6655 O OE1 . GLU C 1 296 ? -21.65413 -24.55220 7.90901   1.000 85.62099  ? 256 GLU C OE1 1 
ATOM   6656 O OE2 . GLU C 1 296 ? -23.44904 -25.53811 8.69339   1.000 100.94139 ? 256 GLU C OE2 1 
ATOM   6657 N N   . MET C 1 297 ? -19.80304 -27.30973 12.53176  1.000 47.26874  ? 257 MET C N   1 
ATOM   6658 C CA  . MET C 1 297 ? -19.77892 -28.67297 13.03533  1.000 55.22913  ? 257 MET C CA  1 
ATOM   6659 C C   . MET C 1 297 ? -21.19301 -29.11417 13.37512  1.000 55.06037  ? 257 MET C C   1 
ATOM   6660 O O   . MET C 1 297 ? -21.97875 -28.34198 13.93086  1.000 52.36468  ? 257 MET C O   1 
ATOM   6661 C CB  . MET C 1 297 ? -18.85995 -28.77983 14.25525  1.000 48.60188  ? 257 MET C CB  1 
ATOM   6662 C CG  . MET C 1 297 ? -19.10024 -27.70511 15.29940  1.000 57.13927  ? 257 MET C CG  1 
ATOM   6663 S SD  . MET C 1 297 ? -18.06873 -27.95735 16.75388  1.000 69.92749  ? 257 MET C SD  1 
ATOM   6664 C CE  . MET C 1 297 ? -17.90273 -29.72962 16.72221  1.000 49.77242  ? 257 MET C CE  1 
ATOM   6665 N N   . ARG C 1 298 ? -21.50697 -30.36194 13.03650  1.000 49.66441  ? 258 ARG C N   1 
ATOM   6666 C CA  . ARG C 1 298 ? -22.80994 -30.95956 13.30876  1.000 47.10414  ? 258 ARG C CA  1 
ATOM   6667 C C   . ARG C 1 298 ? -22.53214 -32.24720 14.06966  1.000 40.83445  ? 258 ARG C C   1 
ATOM   6668 O O   . ARG C 1 298 ? -22.08079 -33.23243 13.47617  1.000 53.05063  ? 258 ARG C O   1 
ATOM   6669 C CB  . ARG C 1 298 ? -23.55628 -31.23872 12.00343  1.000 48.48463  ? 258 ARG C CB  1 
ATOM   6670 C CG  . ARG C 1 298 ? -23.66772 -30.01927 11.09599  1.000 54.39883  ? 258 ARG C CG  1 
ATOM   6671 C CD  . ARG C 1 298 ? -24.57916 -30.25890 9.90671   1.000 58.70739  ? 258 ARG C CD  1 
ATOM   6672 N NE  . ARG C 1 298 ? -24.50053 -29.15833 8.95272   1.000 80.97182  ? 258 ARG C NE  1 
ATOM   6673 C CZ  . ARG C 1 298 ? -25.23773 -28.05769 9.00065   1.000 96.24975  ? 258 ARG C CZ  1 
ATOM   6674 N NH1 . ARG C 1 298 ? -26.14431 -27.87281 9.94578   1.000 86.11860  ? 258 ARG C NH1 1 
ATOM   6675 N NH2 . ARG C 1 298 ? -25.06815 -27.12329 8.06892   1.000 90.08451  ? 258 ARG C NH2 1 
ATOM   6676 N N   . ILE C 1 299 ? -22.79290 -32.25036 15.37845  1.000 47.45707  ? 259 ILE C N   1 
ATOM   6677 C CA  . ILE C 1 299 ? -22.25297 -33.28223 16.25414  1.000 49.98225  ? 259 ILE C CA  1 
ATOM   6678 C C   . ILE C 1 299 ? -23.26370 -33.67499 17.32185  1.000 50.06102  ? 259 ILE C C   1 
ATOM   6679 O O   . ILE C 1 299 ? -24.20057 -32.93739 17.63596  1.000 46.33258  ? 259 ILE C O   1 
ATOM   6680 C CB  . ILE C 1 299 ? -20.93178 -32.82842 16.92529  1.000 49.04870  ? 259 ILE C CB  1 
ATOM   6681 C CG1 . ILE C 1 299 ? -21.03702 -31.38719 17.43535  1.000 45.66141  ? 259 ILE C CG1 1 
ATOM   6682 C CG2 . ILE C 1 299 ? -19.75995 -32.96694 15.96247  1.000 42.73927  ? 259 ILE C CG2 1 
ATOM   6683 C CD1 . ILE C 1 299 ? -21.61064 -31.25177 18.83391  1.000 46.45273  ? 259 ILE C CD1 1 
ATOM   6684 N N   . ASN C 1 300 ? -23.05185 -34.86586 17.87703  1.000 53.25745  ? 260 ASN C N   1 
ATOM   6685 C CA  . ASN C 1 300 ? -23.72008 -35.28978 19.10224  1.000 49.68295  ? 260 ASN C CA  1 
ATOM   6686 C C   . ASN C 1 300 ? -23.10235 -34.52271 20.26783  1.000 55.55083  ? 260 ASN C C   1 
ATOM   6687 O O   . ASN C 1 300 ? -21.91545 -34.68979 20.56826  1.000 54.64137  ? 260 ASN C O   1 
ATOM   6688 C CB  . ASN C 1 300 ? -23.56829 -36.80175 19.26368  1.000 55.51206  ? 260 ASN C CB  1 
ATOM   6689 C CG  . ASN C 1 300 ? -24.27384 -37.35202 20.49423  1.000 50.14965  ? 260 ASN C CG  1 
ATOM   6690 O OD1 . ASN C 1 300 ? -24.22201 -36.77422 21.57570  1.000 52.18804  ? 260 ASN C OD1 1 
ATOM   6691 N ND2 . ASN C 1 300 ? -24.93468 -38.49049 20.32654  1.000 49.75249  ? 260 ASN C ND2 1 
ATOM   6692 N N   . ASN C 1 301 ? -23.90182 -33.67192 20.92196  1.000 54.58950  ? 261 ASN C N   1 
ATOM   6693 C CA  . ASN C 1 301 ? -23.35431 -32.74932 21.91631  1.000 52.23159  ? 261 ASN C CA  1 
ATOM   6694 C C   . ASN C 1 301 ? -22.67137 -33.46868 23.07566  1.000 57.48727  ? 261 ASN C C   1 
ATOM   6695 O O   . ASN C 1 301 ? -21.47577 -33.21850 23.31158  1.000 51.02515  ? 261 ASN C O   1 
ATOM   6696 C CB  . ASN C 1 301 ? -24.45353 -31.78333 22.37632  1.000 46.53594  ? 261 ASN C CB  1 
ATOM   6697 C CG  . ASN C 1 301 ? -23.92106 -30.64282 23.23847  1.000 60.01838  ? 261 ASN C CG  1 
ATOM   6698 O OD1 . ASN C 1 301 ? -22.79768 -30.68863 23.74220  1.000 64.01336  ? 261 ASN C OD1 1 
ATOM   6699 N ND2 . ASN C 1 301 ? -24.73782 -29.61109 23.41245  1.000 66.73903  ? 261 ASN C ND2 1 
ATOM   6700 N N   . PRO C 1 302 ? -23.33982 -34.34669 23.83905  1.000 54.43359  ? 262 PRO C N   1 
ATOM   6701 C CA  . PRO C 1 302 ? -22.62227 -35.00943 24.94402  1.000 55.04620  ? 262 PRO C CA  1 
ATOM   6702 C C   . PRO C 1 302 ? -21.47169 -35.88837 24.48210  1.000 54.07119  ? 262 PRO C C   1 
ATOM   6703 O O   . PRO C 1 302 ? -20.44574 -35.96545 25.16965  1.000 48.54901  ? 262 PRO C O   1 
ATOM   6704 C CB  . PRO C 1 302 ? -23.72097 -35.82593 25.64109  1.000 57.95737  ? 262 PRO C CB  1 
ATOM   6705 C CG  . PRO C 1 302 ? -24.78805 -35.98560 24.62491  1.000 58.60392  ? 262 PRO C CG  1 
ATOM   6706 C CD  . PRO C 1 302 ? -24.76159 -34.73712 23.81192  1.000 49.41755  ? 262 PRO C CD  1 
ATOM   6707 N N   . ALA C 1 303 ? -21.62085 -36.57141 23.34468  1.000 50.40267  ? 263 ALA C N   1 
ATOM   6708 C CA  . ALA C 1 303 ? -20.53574 -37.39904 22.82430  1.000 48.98013  ? 263 ALA C CA  1 
ATOM   6709 C C   . ALA C 1 303 ? -19.27288 -36.57820 22.59288  1.000 56.71288  ? 263 ALA C C   1 
ATOM   6710 O O   . ALA C 1 303 ? -18.17214 -36.98548 22.98173  1.000 54.62245  ? 263 ALA C O   1 
ATOM   6711 C CB  . ALA C 1 303 ? -20.97359 -38.08625 21.53068  1.000 41.88823  ? 263 ALA C CB  1 
ATOM   6712 N N   . LEU C 1 304 ? -19.41197 -35.41968 21.94796  1.000 50.93318  ? 264 LEU C N   1 
ATOM   6713 C CA  . LEU C 1 304 ? -18.24901 -34.58459 21.67009  1.000 46.61943  ? 264 LEU C CA  1 
ATOM   6714 C C   . LEU C 1 304 ? -17.67662 -33.98096 22.94652  1.000 53.00692  ? 264 LEU C C   1 
ATOM   6715 O O   . LEU C 1 304 ? -16.45941 -34.00992 23.16502  1.000 48.75205  ? 264 LEU C O   1 
ATOM   6716 C CB  . LEU C 1 304 ? -18.61796 -33.47994 20.68659  1.000 48.79782  ? 264 LEU C CB  1 
ATOM   6717 C CG  . LEU C 1 304 ? -17.42927 -32.57884 20.36215  1.000 43.64587  ? 264 LEU C CG  1 
ATOM   6718 C CD1 . LEU C 1 304 ? -16.47874 -33.26745 19.39961  1.000 51.00591  ? 264 LEU C CD1 1 
ATOM   6719 C CD2 . LEU C 1 304 ? -17.89043 -31.24480 19.83031  1.000 48.36241  ? 264 LEU C CD2 1 
ATOM   6720 N N   . THR C 1 305 ? -18.54062 -33.40858 23.79129  1.000 51.89896  ? 265 THR C N   1 
ATOM   6721 C CA  . THR C 1 305 ? -18.07344 -32.77607 25.02182  1.000 52.97755  ? 265 THR C CA  1 
ATOM   6722 C C   . THR C 1 305 ? -17.30978 -33.76446 25.89220  1.000 53.56214  ? 265 THR C C   1 
ATOM   6723 O O   . THR C 1 305 ? -16.25951 -33.42913 26.45248  1.000 58.81279  ? 265 THR C O   1 
ATOM   6724 C CB  . THR C 1 305 ? -19.25486 -32.18421 25.79445  1.000 49.44035  ? 265 THR C CB  1 
ATOM   6725 O OG1 . THR C 1 305 ? -19.91257 -31.19714 24.98975  1.000 48.58111  ? 265 THR C OG1 1 
ATOM   6726 C CG2 . THR C 1 305 ? -18.78211 -31.53509 27.08545  1.000 48.69896  ? 265 THR C CG2 1 
ATOM   6727 N N   . SER C 1 306 ? -17.82549 -34.98700 26.02246  1.000 50.85462  ? 266 SER C N   1 
ATOM   6728 C CA  . SER C 1 306 ? -17.12890 -35.99680 26.80993  1.000 48.80523  ? 266 SER C CA  1 
ATOM   6729 C C   . SER C 1 306 ? -15.80950 -36.38520 26.15782  1.000 53.79967  ? 266 SER C C   1 
ATOM   6730 O O   . SER C 1 306 ? -14.82392 -36.66113 26.85156  1.000 53.09178  ? 266 SER C O   1 
ATOM   6731 C CB  . SER C 1 306 ? -18.01326 -37.22684 26.98535  1.000 49.85751  ? 266 SER C CB  1 
ATOM   6732 O OG  . SER C 1 306 ? -18.31200 -37.79983 25.72573  1.000 57.99052  ? 266 SER C OG  1 
ATOM   6733 N N   . GLN C 1 307 ? -15.77581 -36.42259 24.82408  1.000 45.81475  ? 267 GLN C N   1 
ATOM   6734 C CA  . GLN C 1 307 ? -14.53877 -36.75332 24.12673  1.000 44.92606  ? 267 GLN C CA  1 
ATOM   6735 C C   . GLN C 1 307 ? -13.47528 -35.69031 24.35724  1.000 58.63065  ? 267 GLN C C   1 
ATOM   6736 O O   . GLN C 1 307 ? -12.30243 -36.01132 24.58350  1.000 46.65175  ? 267 GLN C O   1 
ATOM   6737 C CB  . GLN C 1 307 ? -14.80276 -36.91941 22.63269  1.000 35.38389  ? 267 GLN C CB  1 
ATOM   6738 C CG  . GLN C 1 307 ? -13.53861 -37.09018 21.80423  1.000 52.38503  ? 267 GLN C CG  1 
ATOM   6739 C CD  . GLN C 1 307 ? -12.79984 -38.37920 22.10862  1.000 42.78709  ? 267 GLN C CD  1 
ATOM   6740 O OE1 . GLN C 1 307 ? -13.05126 -39.41114 21.48895  1.000 48.82645  ? 267 GLN C OE1 1 
ATOM   6741 N NE2 . GLN C 1 307 ? -11.86441 -38.31921 23.05115  1.000 43.18567  ? 267 GLN C NE2 1 
ATOM   6742 N N   . VAL C 1 308 ? -13.86636 -34.41687 24.30172  1.000 47.91365  ? 268 VAL C N   1 
ATOM   6743 C CA  . VAL C 1 308 ? -12.91663 -33.33865 24.55403  1.000 45.06129  ? 268 VAL C CA  1 
ATOM   6744 C C   . VAL C 1 308 ? -12.38305 -33.42241 25.97826  1.000 45.01284  ? 268 VAL C C   1 
ATOM   6745 O O   . VAL C 1 308 ? -11.18725 -33.21960 26.22175  1.000 59.66053  ? 268 VAL C O   1 
ATOM   6746 C CB  . VAL C 1 308 ? -13.57149 -31.97544 24.26389  1.000 56.99063  ? 268 VAL C CB  1 
ATOM   6747 C CG1 . VAL C 1 308 ? -12.68964 -30.83877 24.75914  1.000 48.57805  ? 268 VAL C CG1 1 
ATOM   6748 C CG2 . VAL C 1 308 ? -13.85582 -31.83417 22.77194  1.000 43.64546  ? 268 VAL C CG2 1 
ATOM   6749 N N   . MET C 1 309 ? -13.25506 -33.74309 26.93747  1.000 51.07875  ? 269 MET C N   1 
ATOM   6750 C CA  . MET C 1 309 ? -12.82150 -33.86284 28.32649  1.000 51.18986  ? 269 MET C CA  1 
ATOM   6751 C C   . MET C 1 309 ? -11.81570 -34.99415 28.50298  1.000 53.20613  ? 269 MET C C   1 
ATOM   6752 O O   . MET C 1 309 ? -10.89234 -34.88852 29.31916  1.000 58.96763  ? 269 MET C O   1 
ATOM   6753 C CB  . MET C 1 309 ? -14.02973 -34.06944 29.23884  1.000 55.55254  ? 269 MET C CB  1 
ATOM   6754 C CG  . MET C 1 309 ? -14.96598 -32.87657 29.28165  1.000 61.09095  ? 269 MET C CG  1 
ATOM   6755 S SD  . MET C 1 309 ? -16.47089 -33.18423 30.21680  1.000 65.87917  ? 269 MET C SD  1 
ATOM   6756 C CE  . MET C 1 309 ? -15.85554 -33.01637 31.88854  1.000 61.36866  ? 269 MET C CE  1 
ATOM   6757 N N   . ILE C 1 310 ? -11.97958 -36.08835 27.75470  1.000 50.17290  ? 270 ILE C N   1 
ATOM   6758 C CA  . ILE C 1 310 ? -11.01506 -37.18211 27.83368  1.000 54.59036  ? 270 ILE C CA  1 
ATOM   6759 C C   . ILE C 1 310 ? -9.67949  -36.75608 27.23403  1.000 50.78878  ? 270 ILE C C   1 
ATOM   6760 O O   . ILE C 1 310 ? -8.61400  -37.04874 27.78913  1.000 57.87974  ? 270 ILE C O   1 
ATOM   6761 C CB  . ILE C 1 310 ? -11.57620 -38.44832 27.15569  1.000 54.39687  ? 270 ILE C CB  1 
ATOM   6762 C CG1 . ILE C 1 310 ? -12.25548 -39.35907 28.18715  1.000 47.67443  ? 270 ILE C CG1 1 
ATOM   6763 C CG2 . ILE C 1 310 ? -10.47856 -39.21410 26.41425  1.000 46.41402  ? 270 ILE C CG2 1 
ATOM   6764 C CD1 . ILE C 1 310 ? -13.40682 -38.72056 28.94141  1.000 50.26857  ? 270 ILE C CD1 1 
ATOM   6765 N N   . ALA C 1 311 ? -9.71256  -36.04703 26.10233  1.000 51.28309  ? 271 ALA C N   1 
ATOM   6766 C CA  . ALA C 1 311 ? -8.48008  -35.51813 25.52564  1.000 48.35569  ? 271 ALA C CA  1 
ATOM   6767 C C   . ALA C 1 311 ? -7.81654  -34.51455 26.46133  1.000 54.07029  ? 271 ALA C C   1 
ATOM   6768 O O   . ALA C 1 311 ? -6.58377  -34.43839 26.52945  1.000 55.97458  ? 271 ALA C O   1 
ATOM   6769 C CB  . ALA C 1 311 ? -8.76415  -34.87916 24.16699  1.000 46.28796  ? 271 ALA C CB  1 
ATOM   6770 N N   . SER C 1 312 ? -8.61901  -33.72686 27.18282  1.000 47.79794  ? 272 SER C N   1 
ATOM   6771 C CA  . SER C 1 312 ? -8.06012  -32.78134 28.14313  1.000 50.94644  ? 272 SER C CA  1 
ATOM   6772 C C   . SER C 1 312 ? -7.41065  -33.49551 29.32012  1.000 54.90016  ? 272 SER C C   1 
ATOM   6773 O O   . SER C 1 312 ? -6.41784  -33.00445 29.86763  1.000 52.10883  ? 272 SER C O   1 
ATOM   6774 C CB  . SER C 1 312 ? -9.14543  -31.82522 28.63591  1.000 52.04690  ? 272 SER C CB  1 
ATOM   6775 O OG  . SER C 1 312 ? -9.63268  -31.02284 27.57506  1.000 56.39590  ? 272 SER C OG  1 
ATOM   6776 N N   . ALA C 1 313 ? -7.96605  -34.63491 29.73925  1.000 55.15072  ? 273 ALA C N   1 
ATOM   6777 C CA  . ALA C 1 313 ? -7.31920  -35.43111 30.77671  1.000 49.38873  ? 273 ALA C CA  1 
ATOM   6778 C C   . ALA C 1 313 ? -5.91375  -35.83506 30.35262  1.000 55.69950  ? 273 ALA C C   1 
ATOM   6779 O O   . ALA C 1 313 ? -4.98485  -35.84353 31.16976  1.000 63.17661  ? 273 ALA C O   1 
ATOM   6780 C CB  . ALA C 1 313 ? -8.16409  -36.66285 31.09531  1.000 47.36017  ? 273 ALA C CB  1 
ATOM   6781 N N   . ARG C 1 314 ? -5.74933  -36.19352 29.07785  1.000 59.47611  ? 274 ARG C N   1 
ATOM   6782 C CA  . ARG C 1 314 ? -4.42582  -36.47051 28.52932  1.000 57.25767  ? 274 ARG C CA  1 
ATOM   6783 C C   . ARG C 1 314 ? -3.51906  -35.24833 28.63528  1.000 49.93105  ? 274 ARG C C   1 
ATOM   6784 O O   . ARG C 1 314 ? -2.34666  -35.36042 29.01178  1.000 57.84419  ? 274 ARG C O   1 
ATOM   6785 C CB  . ARG C 1 314 ? -4.56886  -36.92688 27.07649  1.000 47.20873  ? 274 ARG C CB  1 
ATOM   6786 C CG  . ARG C 1 314 ? -3.27537  -37.25263 26.36961  1.000 50.43665  ? 274 ARG C CG  1 
ATOM   6787 C CD  . ARG C 1 314 ? -3.54576  -37.65452 24.92749  1.000 55.17474  ? 274 ARG C CD  1 
ATOM   6788 N NE  . ARG C 1 314 ? -4.40085  -38.83329 24.83899  1.000 55.77164  ? 274 ARG C NE  1 
ATOM   6789 C CZ  . ARG C 1 314 ? -5.63599  -38.82813 24.35547  1.000 49.92330  ? 274 ARG C CZ  1 
ATOM   6790 N NH1 . ARG C 1 314 ? -6.18389  -37.72553 23.87108  1.000 49.56293  ? 274 ARG C NH1 1 
ATOM   6791 N NH2 . ARG C 1 314 ? -6.33584  -39.95918 24.34994  1.000 46.14819  ? 274 ARG C NH2 1 
ATOM   6792 N N   . ALA C 1 315 ? -4.04638  -34.06808 28.29504  1.000 57.42210  ? 275 ALA C N   1 
ATOM   6793 C CA  . ALA C 1 315 ? -3.24754  -32.84817 28.35758  1.000 56.80391  ? 275 ALA C CA  1 
ATOM   6794 C C   . ALA C 1 315 ? -2.88423  -32.48211 29.79143  1.000 56.82719  ? 275 ALA C C   1 
ATOM   6795 O O   . ALA C 1 315 ? -1.81403  -31.91112 30.02957  1.000 54.96859  ? 275 ALA C O   1 
ATOM   6796 C CB  . ALA C 1 315 ? -3.99370  -31.69479 27.68974  1.000 49.05162  ? 275 ALA C CB  1 
ATOM   6797 N N   . ALA C 1 316 ? -3.76417  -32.78614 30.75037  1.000 51.60356  ? 276 ALA C N   1 
ATOM   6798 C CA  . ALA C 1 316 ? -3.50195  -32.45078 32.14754  1.000 51.67460  ? 276 ALA C CA  1 
ATOM   6799 C C   . ALA C 1 316 ? -2.22363  -33.11086 32.65124  1.000 52.30353  ? 276 ALA C C   1 
ATOM   6800 O O   . ALA C 1 316 ? -1.49199  -32.52744 33.45913  1.000 57.50103  ? 276 ALA C O   1 
ATOM   6801 C CB  . ALA C 1 316 ? -4.69403  -32.85880 33.01430  1.000 51.43600  ? 276 ALA C CB  1 
ATOM   6802 N N   . MET C 1 317 ? -1.94436  -34.33411 32.19638  1.000 52.40025  ? 277 MET C N   1 
ATOM   6803 C CA  . MET C 1 317 ? -0.73503  -35.04199 32.60063  1.000 48.51197  ? 277 MET C CA  1 
ATOM   6804 C C   . MET C 1 317 ? 0.53973   -34.40188 32.06554  1.000 54.91324  ? 277 MET C C   1 
ATOM   6805 O O   . MET C 1 317 ? 1.63263   -34.80701 32.47520  1.000 60.16819  ? 277 MET C O   1 
ATOM   6806 C CB  . MET C 1 317 ? -0.80243  -36.49910 32.14363  1.000 50.23829  ? 277 MET C CB  1 
ATOM   6807 C CG  . MET C 1 317 ? -1.97080  -37.27534 32.72122  1.000 57.83357  ? 277 MET C CG  1 
ATOM   6808 S SD  . MET C 1 317 ? -1.90006  -37.40404 34.51580  1.000 62.72094  ? 277 MET C SD  1 
ATOM   6809 C CE  . MET C 1 317 ? -0.48646  -38.48719 34.71519  1.000 58.48097  ? 277 MET C CE  1 
ATOM   6810 N N   . ARG C 1 318 ? 0.43468   -33.41847 31.17402  1.000 50.96954  ? 278 ARG C N   1 
ATOM   6811 C CA  . ARG C 1 318 ? 1.59989   -32.80734 30.55029  1.000 44.05013  ? 278 ARG C CA  1 
ATOM   6812 C C   . ARG C 1 318 ? 1.81820   -31.36431 30.98845  1.000 49.09927  ? 278 ARG C C   1 
ATOM   6813 O O   . ARG C 1 318 ? 2.66590   -30.67674 30.41423  1.000 51.34374  ? 278 ARG C O   1 
ATOM   6814 C CB  . ARG C 1 318 ? 1.47081   -32.88380 29.02735  1.000 44.11417  ? 278 ARG C CB  1 
ATOM   6815 C CG  . ARG C 1 318 ? 1.30981   -34.30440 28.50996  1.000 42.86410  ? 278 ARG C CG  1 
ATOM   6816 C CD  . ARG C 1 318 ? 0.86513   -34.35000 27.05867  1.000 43.66469  ? 278 ARG C CD  1 
ATOM   6817 N NE  . ARG C 1 318 ? 1.08318   -35.66896 26.47432  1.000 58.67898  ? 278 ARG C NE  1 
ATOM   6818 C CZ  . ARG C 1 318 ? 0.42437   -36.14584 25.42692  1.000 55.07858  ? 278 ARG C CZ  1 
ATOM   6819 N NH1 . ARG C 1 318 ? -0.53088  -35.44822 24.83481  1.000 57.79802  ? 278 ARG C NH1 1 
ATOM   6820 N NH2 . ARG C 1 318 ? 0.73251   -37.35290 24.96115  1.000 61.85999  ? 278 ARG C NH2 1 
ATOM   6821 N N   . GLN C 1 319 ? 1.07793   -30.88585 31.98227  1.000 48.10080  ? 279 GLN C N   1 
ATOM   6822 C CA  . GLN C 1 319 ? 1.15293   -29.49782 32.41159  1.000 52.13378  ? 279 GLN C CA  1 
ATOM   6823 C C   . GLN C 1 319 ? 1.84189   -29.37825 33.76491  1.000 47.92182  ? 279 GLN C C   1 
ATOM   6824 O O   . GLN C 1 319 ? 1.93128   -30.33546 34.53729  1.000 54.63824  ? 279 GLN C O   1 
ATOM   6825 C CB  . GLN C 1 319 ? -0.24787  -28.86962 32.48588  1.000 53.57143  ? 279 GLN C CB  1 
ATOM   6826 C CG  . GLN C 1 319 ? -1.03687  -28.99921 31.20431  1.000 47.22506  ? 279 GLN C CG  1 
ATOM   6827 C CD  . GLN C 1 319 ? -0.21735  -28.62663 29.98922  1.000 46.94052  ? 279 GLN C CD  1 
ATOM   6828 O OE1 . GLN C 1 319 ? 0.34488   -27.53148 29.91260  1.000 56.71548  ? 279 GLN C OE1 1 
ATOM   6829 N NE2 . GLN C 1 319 ? -0.14060  -29.53996 29.02985  1.000 44.26521  ? 279 GLN C NE2 1 
ATOM   6830 N N   . LYS C 1 320 ? 2.33959   -28.18151 34.03132  1.000 58.00698  ? 280 LYS C N   1 
ATOM   6831 C CA  . LYS C 1 320 ? 2.77392   -27.79945 35.35928  1.000 58.26795  ? 280 LYS C CA  1 
ATOM   6832 C C   . LYS C 1 320 ? 1.54961   -27.55180 36.23665  1.000 58.94455  ? 280 LYS C C   1 
ATOM   6833 O O   . LYS C 1 320 ? 0.45973   -27.29365 35.72455  1.000 62.04841  ? 280 LYS C O   1 
ATOM   6834 C CB  . LYS C 1 320 ? 3.65637   -26.55901 35.26694  1.000 61.88266  ? 280 LYS C CB  1 
ATOM   6835 C CG  . LYS C 1 320 ? 4.92611   -26.80184 34.45677  1.000 62.82324  ? 280 LYS C CG  1 
ATOM   6836 C CD  . LYS C 1 320 ? 5.77683   -25.55381 34.31140  1.000 67.17074  ? 280 LYS C CD  1 
ATOM   6837 C CE  . LYS C 1 320 ? 6.93014   -25.82239 33.35382  1.000 69.05947  ? 280 LYS C CE  1 
ATOM   6838 N NZ  . LYS C 1 320 ? 7.91967   -24.71262 33.29989  1.000 79.48903  ? 280 LYS C NZ  1 
ATOM   6839 N N   . PRO C 1 321 ? 1.69654   -27.63482 37.56080  1.000 65.93576  ? 281 PRO C N   1 
ATOM   6840 C CA  . PRO C 1 321 ? 0.54829   -27.39282 38.44740  1.000 61.36880  ? 281 PRO C CA  1 
ATOM   6841 C C   . PRO C 1 321 ? -0.10757  -26.03865 38.19400  1.000 58.27317  ? 281 PRO C C   1 
ATOM   6842 O O   . PRO C 1 321 ? 0.56211   -25.03173 37.94456  1.000 66.65578  ? 281 PRO C O   1 
ATOM   6843 C CB  . PRO C 1 321 ? 1.16824   -27.46365 39.84512  1.000 56.99420  ? 281 PRO C CB  1 
ATOM   6844 C CG  . PRO C 1 321 ? 2.36478   -28.34605 39.66615  1.000 64.74612  ? 281 PRO C CG  1 
ATOM   6845 C CD  . PRO C 1 321 ? 2.90133   -28.02717 38.31369  1.000 53.39660  ? 281 PRO C CD  1 
ATOM   6846 N N   . GLY C 1 322 ? -1.43752  -26.02611 38.26983  1.000 63.73646  ? 282 GLY C N   1 
ATOM   6847 C CA  . GLY C 1 322 ? -2.21282  -24.82652 38.01863  1.000 62.33507  ? 282 GLY C CA  1 
ATOM   6848 C C   . GLY C 1 322 ? -3.51678  -25.10760 37.29846  1.000 67.89775  ? 282 GLY C C   1 
ATOM   6849 O O   . GLY C 1 322 ? -3.83394  -26.26506 37.01104  1.000 63.71542  ? 282 GLY C O   1 
ATOM   6850 N N   . ALA C 1 323 ? -4.28388  -24.06156 37.00295  1.000 60.76406  ? 283 ALA C N   1 
ATOM   6851 C CA  . ALA C 1 323 ? -5.54226  -24.18254 36.27961  1.000 54.38534  ? 283 ALA C CA  1 
ATOM   6852 C C   . ALA C 1 323 ? -5.40390  -23.55202 34.89992  1.000 56.80664  ? 283 ALA C C   1 
ATOM   6853 O O   . ALA C 1 323 ? -4.82591  -22.46936 34.75612  1.000 68.26327  ? 283 ALA C O   1 
ATOM   6854 C CB  . ALA C 1 323 ? -6.69497  -23.52462 37.04555  1.000 60.91793  ? 283 ALA C CB  1 
ATOM   6855 N N   . TYR C 1 324 ? -5.93255  -24.23625 33.88634  1.000 58.40083  ? 284 TYR C N   1 
ATOM   6856 C CA  . TYR C 1 324 ? -5.79299  -23.81724 32.49967  1.000 56.02651  ? 284 TYR C CA  1 
ATOM   6857 C C   . TYR C 1 324 ? -7.12981  -23.90703 31.78058  1.000 60.94901  ? 284 TYR C C   1 
ATOM   6858 O O   . TYR C 1 324 ? -7.87537  -24.87644 31.95506  1.000 56.41533  ? 284 TYR C O   1 
ATOM   6859 C CB  . TYR C 1 324 ? -4.78114  -24.69094 31.73919  1.000 54.72152  ? 284 TYR C CB  1 
ATOM   6860 C CG  . TYR C 1 324 ? -3.42638  -24.85787 32.38917  1.000 53.56504  ? 284 TYR C CG  1 
ATOM   6861 C CD1 . TYR C 1 324 ? -3.23593  -25.76182 33.42681  1.000 57.40264  ? 284 TYR C CD1 1 
ATOM   6862 C CD2 . TYR C 1 324 ? -2.32591  -24.14237 31.93465  1.000 60.54492  ? 284 TYR C CD2 1 
ATOM   6863 C CE1 . TYR C 1 324 ? -1.99420  -25.92839 34.01330  1.000 62.99356  ? 284 TYR C CE1 1 
ATOM   6864 C CE2 . TYR C 1 324 ? -1.07934  -24.30365 32.51294  1.000 48.35506  ? 284 TYR C CE2 1 
ATOM   6865 C CZ  . TYR C 1 324 ? -0.91944  -25.19787 33.55090  1.000 58.27417  ? 284 TYR C CZ  1 
ATOM   6866 O OH  . TYR C 1 324 ? 0.31979   -25.35943 34.12736  1.000 57.17171  ? 284 TYR C OH  1 
ATOM   6867 N N   . THR C 1 325 ? -7.42337  -22.89701 30.96557  1.000 54.10457  ? 285 THR C N   1 
ATOM   6868 C CA  . THR C 1 325 ? -8.41235  -23.05724 29.91252  1.000 51.74114  ? 285 THR C CA  1 
ATOM   6869 C C   . THR C 1 325 ? -7.75604  -23.69016 28.68550  1.000 50.90679  ? 285 THR C C   1 
ATOM   6870 O O   . THR C 1 325 ? -6.53708  -23.87185 28.62488  1.000 59.36228  ? 285 THR C O   1 
ATOM   6871 C CB  . THR C 1 325 ? -9.05714  -21.71603 29.55466  1.000 49.43828  ? 285 THR C CB  1 
ATOM   6872 O OG1 . THR C 1 325 ? -8.05527  -20.79687 29.10400  1.000 47.76588  ? 285 THR C OG1 1 
ATOM   6873 C CG2 . THR C 1 325 ? -9.76755  -21.12974 30.76055  1.000 49.37638  ? 285 THR C CG2 1 
ATOM   6874 N N   . MET C 1 326 ? -8.58043  -24.03057 27.69207  1.000 44.45170  ? 286 MET C N   1 
ATOM   6875 C CA  . MET C 1 326 ? -8.06830  -24.77191 26.54452  1.000 45.60260  ? 286 MET C CA  1 
ATOM   6876 C C   . MET C 1 326 ? -7.20857  -23.92175 25.61345  1.000 54.65337  ? 286 MET C C   1 
ATOM   6877 O O   . MET C 1 326 ? -6.47469  -24.48557 24.79458  1.000 65.06028  ? 286 MET C O   1 
ATOM   6878 C CB  . MET C 1 326 ? -9.21824  -25.40057 25.75665  1.000 47.88470  ? 286 MET C CB  1 
ATOM   6879 C CG  . MET C 1 326 ? -9.94107  -26.50325 26.50840  1.000 51.52797  ? 286 MET C CG  1 
ATOM   6880 S SD  . MET C 1 326 ? -10.97120 -27.51811 25.43881  1.000 54.59846  ? 286 MET C SD  1 
ATOM   6881 C CE  . MET C 1 326 ? -9.73484  -28.56458 24.67224  1.000 55.15511  ? 286 MET C CE  1 
ATOM   6882 N N   . ILE C 1 327 ? -7.27061  -22.59231 25.70892  1.000 48.79142  ? 287 ILE C N   1 
ATOM   6883 C CA  . ILE C 1 327 ? -6.44482  -21.74822 24.84857  1.000 52.42204  ? 287 ILE C CA  1 
ATOM   6884 C C   . ILE C 1 327 ? -5.10424  -21.47180 25.51870  1.000 53.88904  ? 287 ILE C C   1 
ATOM   6885 O O   . ILE C 1 327 ? -4.28998  -20.69636 25.00513  1.000 45.40931  ? 287 ILE C O   1 
ATOM   6886 C CB  . ILE C 1 327 ? -7.15354  -20.42884 24.49118  1.000 48.76354  ? 287 ILE C CB  1 
ATOM   6887 C CG1 . ILE C 1 327 ? -7.39688  -19.58710 25.74421  1.000 45.13110  ? 287 ILE C CG1 1 
ATOM   6888 C CG2 . ILE C 1 327 ? -8.45270  -20.70305 23.74902  1.000 43.74299  ? 287 ILE C CG2 1 
ATOM   6889 C CD1 . ILE C 1 327 ? -7.97314  -18.21776 25.45119  1.000 46.72654  ? 287 ILE C CD1 1 
ATOM   6890 N N   . GLU C 1 328 ? -4.85806  -22.11230 26.66047  1.000 51.78982  ? 288 GLU C N   1 
ATOM   6891 C CA  . GLU C 1 328 ? -3.59656  -21.97479 27.37664  1.000 54.99500  ? 288 GLU C CA  1 
ATOM   6892 C C   . GLU C 1 328 ? -2.76560  -23.24977 27.33073  1.000 54.08410  ? 288 GLU C C   1 
ATOM   6893 O O   . GLU C 1 328 ? -1.79273  -23.37088 28.08151  1.000 59.60067  ? 288 GLU C O   1 
ATOM   6894 C CB  . GLU C 1 328 ? -3.84492  -21.57629 28.83447  1.000 44.63270  ? 288 GLU C CB  1 
ATOM   6895 C CG  . GLU C 1 328 ? -4.78350  -20.39944 29.02454  1.000 54.84337  ? 288 GLU C CG  1 
ATOM   6896 C CD  . GLU C 1 328 ? -5.01041  -20.07030 30.48789  1.000 66.78262  ? 288 GLU C CD  1 
ATOM   6897 O OE1 . GLU C 1 328 ? -4.01638  -19.95615 31.23396  1.000 66.20295  ? 288 GLU C OE1 1 
ATOM   6898 O OE2 . GLU C 1 328 ? -6.18275  -19.92938 30.89383  1.000 63.80087  ? 288 GLU C OE2 1 
ATOM   6899 N N   . ILE C 1 329 ? -3.12163  -24.19871 26.47012  1.000 50.61799  ? 289 ILE C N   1 
ATOM   6900 C CA  . ILE C 1 329 ? -2.43838  -25.48809 26.39879  1.000 52.43772  ? 289 ILE C CA  1 
ATOM   6901 C C   . ILE C 1 329 ? -2.06615  -25.78284 24.95037  1.000 58.36109  ? 289 ILE C C   1 
ATOM   6902 O O   . ILE C 1 329 ? -2.89755  -25.59591 24.04948  1.000 56.33390  ? 289 ILE C O   1 
ATOM   6903 C CB  . ILE C 1 329 ? -3.30698  -26.60539 26.99930  1.000 57.07947  ? 289 ILE C CB  1 
ATOM   6904 C CG1 . ILE C 1 329 ? -3.54841  -26.32654 28.48460  1.000 54.07124  ? 289 ILE C CG1 1 
ATOM   6905 C CG2 . ILE C 1 329 ? -2.66388  -27.97599 26.79582  1.000 52.83421  ? 289 ILE C CG2 1 
ATOM   6906 C CD1 . ILE C 1 329 ? -4.44713  -27.31868 29.15525  1.000 63.67083  ? 289 ILE C CD1 1 
ATOM   6907 N N   . PRO C 1 330 ? -0.83393  -26.21973 24.68090  1.000 51.08893  ? 290 PRO C N   1 
ATOM   6908 C CA  . PRO C 1 330 ? -0.46418  -26.60439 23.31142  1.000 58.61477  ? 290 PRO C CA  1 
ATOM   6909 C C   . PRO C 1 330 ? -1.39298  -27.67344 22.75226  1.000 55.85944  ? 290 PRO C C   1 
ATOM   6910 O O   . PRO C 1 330 ? -1.73457  -28.64443 23.43100  1.000 52.47641  ? 290 PRO C O   1 
ATOM   6911 C CB  . PRO C 1 330 ? 0.96966   -27.12972 23.45950  1.000 55.93111  ? 290 PRO C CB  1 
ATOM   6912 C CG  . PRO C 1 330 ? 1.47177   -26.56445 24.74117  1.000 47.16592  ? 290 PRO C CG  1 
ATOM   6913 C CD  . PRO C 1 330 ? 0.28480   -26.35903 25.62896  1.000 50.07322  ? 290 PRO C CD  1 
ATOM   6914 N N   . ILE C 1 331 ? -1.81233  -27.46658 21.49967  1.000 46.63460  ? 291 ILE C N   1 
ATOM   6915 C CA  . ILE C 1 331 ? -2.76595  -28.36622 20.85176  1.000 48.41024  ? 291 ILE C CA  1 
ATOM   6916 C C   . ILE C 1 331 ? -2.25247  -29.80198 20.85687  1.000 51.45394  ? 291 ILE C C   1 
ATOM   6917 O O   . ILE C 1 331 ? -3.02445  -30.75302 21.04012  1.000 51.01996  ? 291 ILE C O   1 
ATOM   6918 C CB  . ILE C 1 331 ? -3.05961  -27.87801 19.42006  1.000 50.57386  ? 291 ILE C CB  1 
ATOM   6919 C CG1 . ILE C 1 331 ? -3.73251  -26.50449 19.44645  1.000 46.54003  ? 291 ILE C CG1 1 
ATOM   6920 C CG2 . ILE C 1 331 ? -3.93553  -28.87516 18.67430  1.000 46.69817  ? 291 ILE C CG2 1 
ATOM   6921 C CD1 . ILE C 1 331 ? -3.97337  -25.92660 18.07110  1.000 47.16454  ? 291 ILE C CD1 1 
ATOM   6922 N N   . ILE C 1 332 ? -0.94146  -29.98178 20.67016  1.000 44.28190  ? 292 ILE C N   1 
ATOM   6923 C CA  . ILE C 1 332 ? -0.37240  -31.32492 20.58946  1.000 43.13310  ? 292 ILE C CA  1 
ATOM   6924 C C   . ILE C 1 332 ? -0.53462  -32.07189 21.90762  1.000 50.61870  ? 292 ILE C C   1 
ATOM   6925 O O   . ILE C 1 332 ? -0.55487  -33.30893 21.92965  1.000 48.33134  ? 292 ILE C O   1 
ATOM   6926 C CB  . ILE C 1 332 ? 1.10586   -31.25653 20.15117  1.000 58.00949  ? 292 ILE C CB  1 
ATOM   6927 C CG1 . ILE C 1 332 ? 1.58514   -32.62124 19.65625  1.000 48.62958  ? 292 ILE C CG1 1 
ATOM   6928 C CG2 . ILE C 1 332 ? 1.98757   -30.75635 21.28877  1.000 49.86292  ? 292 ILE C CG2 1 
ATOM   6929 C CD1 . ILE C 1 332 ? 2.96594   -32.59727 19.04712  1.000 50.39854  ? 292 ILE C CD1 1 
ATOM   6930 N N   . ASP C 1 333 ? -0.65265  -31.34601 23.02330  1.000 48.68017  ? 293 ASP C N   1 
ATOM   6931 C CA  . ASP C 1 333 ? -0.78433  -31.99456 24.32399  1.000 51.68993  ? 293 ASP C CA  1 
ATOM   6932 C C   . ASP C 1 333 ? -2.09363  -32.75941 24.47354  1.000 54.28408  ? 293 ASP C C   1 
ATOM   6933 O O   . ASP C 1 333 ? -2.17020  -33.66840 25.30641  1.000 49.32882  ? 293 ASP C O   1 
ATOM   6934 C CB  . ASP C 1 333 ? -0.66016  -30.96098 25.44421  1.000 51.93098  ? 293 ASP C CB  1 
ATOM   6935 C CG  . ASP C 1 333 ? 0.76238   -30.47760 25.63325  1.000 56.58171  ? 293 ASP C CG  1 
ATOM   6936 O OD1 . ASP C 1 333 ? 1.66462   -31.00350 24.94763  1.000 72.26777  ? 293 ASP C OD1 1 
ATOM   6937 O OD2 . ASP C 1 333 ? 0.97869   -29.57458 26.46732  1.000 63.96100  ? 293 ASP C OD2 1 
ATOM   6938 N N   . PHE C 1 334 ? -3.11847  -32.41966 23.69257  1.000 46.38148  ? 294 PHE C N   1 
ATOM   6939 C CA  . PHE C 1 334 ? -4.37888  -33.14869 23.73746  1.000 52.86849  ? 294 PHE C CA  1 
ATOM   6940 C C   . PHE C 1 334 ? -4.35468  -34.42992 22.91380  1.000 56.19863  ? 294 PHE C C   1 
ATOM   6941 O O   . PHE C 1 334 ? -5.30812  -35.21260 22.98845  1.000 46.77774  ? 294 PHE C O   1 
ATOM   6942 C CB  . PHE C 1 334 ? -5.52894  -32.25877 23.25476  1.000 51.53660  ? 294 PHE C CB  1 
ATOM   6943 C CG  . PHE C 1 334 ? -5.77759  -31.05925 24.12371  1.000 49.93367  ? 294 PHE C CG  1 
ATOM   6944 C CD1 . PHE C 1 334 ? -6.58662  -31.15518 25.24455  1.000 48.58827  ? 294 PHE C CD1 1 
ATOM   6945 C CD2 . PHE C 1 334 ? -5.21072  -29.83393 23.81589  1.000 48.95565  ? 294 PHE C CD2 1 
ATOM   6946 C CE1 . PHE C 1 334 ? -6.82146  -30.05509 26.04373  1.000 45.51755  ? 294 PHE C CE1 1 
ATOM   6947 C CE2 . PHE C 1 334 ? -5.44243  -28.72825 24.61170  1.000 48.77216  ? 294 PHE C CE2 1 
ATOM   6948 C CZ  . PHE C 1 334 ? -6.24904  -28.83933 25.72734  1.000 54.48934  ? 294 PHE C CZ  1 
ATOM   6949 N N   . LEU C 1 335 ? -3.30040  -34.66685 22.14114  1.000 50.89696  ? 295 LEU C N   1 
ATOM   6950 C CA  . LEU C 1 335 ? -3.25998  -35.77029 21.19357  1.000 49.26986  ? 295 LEU C CA  1 
ATOM   6951 C C   . LEU C 1 335 ? -2.45110  -36.93716 21.74412  1.000 62.04748  ? 295 LEU C C   1 
ATOM   6952 O O   . LEU C 1 335 ? -1.44949  -36.74636 22.44103  1.000 56.03792  ? 295 LEU C O   1 
ATOM   6953 C CB  . LEU C 1 335 ? -2.66010  -35.31955 19.86045  1.000 49.82640  ? 295 LEU C CB  1 
ATOM   6954 C CG  . LEU C 1 335 ? -3.45850  -34.29075 19.06379  1.000 52.57998  ? 295 LEU C CG  1 
ATOM   6955 C CD1 . LEU C 1 335 ? -2.56970  -33.60443 18.04900  1.000 65.64858  ? 295 LEU C CD1 1 
ATOM   6956 C CD2 . LEU C 1 335 ? -4.62965  -34.95974 18.37124  1.000 43.66904  ? 295 LEU C CD2 1 
ATOM   6957 N N   . TYR C 1 336 ? -2.90199  -38.14643 21.42592  1.000 55.16462  ? 296 TYR C N   1 
ATOM   6958 C CA  . TYR C 1 336 ? -2.18219  -39.37053 21.74274  1.000 55.01893  ? 296 TYR C CA  1 
ATOM   6959 C C   . TYR C 1 336 ? -1.22035  -39.72431 20.61721  1.000 55.47278  ? 296 TYR C C   1 
ATOM   6960 O O   . TYR C 1 336 ? -1.55486  -39.59390 19.43610  1.000 58.13558  ? 296 TYR C O   1 
ATOM   6961 C CB  . TYR C 1 336 ? -3.16046  -40.52533 21.96603  1.000 47.89658  ? 296 TYR C CB  1 
ATOM   6962 C CG  . TYR C 1 336 ? -2.49082  -41.87616 22.08001  1.000 52.99324  ? 296 TYR C CG  1 
ATOM   6963 C CD1 . TYR C 1 336 ? -1.81242  -42.24839 23.23289  1.000 58.24040  ? 296 TYR C CD1 1 
ATOM   6964 C CD2 . TYR C 1 336 ? -2.51754  -42.77201 21.01836  1.000 54.29674  ? 296 TYR C CD2 1 
ATOM   6965 C CE1 . TYR C 1 336 ? -1.19290  -43.48484 23.33046  1.000 58.11466  ? 296 TYR C CE1 1 
ATOM   6966 C CE2 . TYR C 1 336 ? -1.89881  -44.00545 21.10476  1.000 51.83115  ? 296 TYR C CE2 1 
ATOM   6967 C CZ  . TYR C 1 336 ? -1.24011  -44.35805 22.26338  1.000 55.60261  ? 296 TYR C CZ  1 
ATOM   6968 O OH  . TYR C 1 336 ? -0.62628  -45.58751 22.35025  1.000 58.66864  ? 296 TYR C OH  1 
ATOM   6969 N N   . GLY C 1 337 ? -0.02894  -40.17680 20.98621  1.000 52.83395  ? 297 GLY C N   1 
ATOM   6970 C CA  . GLY C 1 337 ? 0.92866   -40.68074 20.02326  1.000 47.68612  ? 297 GLY C CA  1 
ATOM   6971 C C   . GLY C 1 337 ? 2.30693   -40.07964 20.21274  1.000 56.07410  ? 297 GLY C C   1 
ATOM   6972 O O   . GLY C 1 337 ? 2.53296   -39.19511 21.03609  1.000 53.06312  ? 297 GLY C O   1 
ATOM   6973 N N   . ASP C 1 338 ? 3.23968   -40.60441 19.42253  1.000 54.74444  ? 298 ASP C N   1 
ATOM   6974 C CA  . ASP C 1 338 ? 4.59906   -40.08529 19.39787  1.000 54.65755  ? 298 ASP C CA  1 
ATOM   6975 C C   . ASP C 1 338 ? 4.60156   -38.65850 18.86303  1.000 53.54723  ? 298 ASP C C   1 
ATOM   6976 O O   . ASP C 1 338 ? 3.93572   -38.35848 17.86723  1.000 54.19671  ? 298 ASP C O   1 
ATOM   6977 C CB  . ASP C 1 338 ? 5.48041   -40.98639 18.53364  1.000 49.24175  ? 298 ASP C CB  1 
ATOM   6978 C CG  . ASP C 1 338 ? 6.87456   -40.42948 18.33653  1.000 64.06826  ? 298 ASP C CG  1 
ATOM   6979 O OD1 . ASP C 1 338 ? 7.70126   -40.54639 19.26499  1.000 62.89563  ? 298 ASP C OD1 1 
ATOM   6980 O OD2 . ASP C 1 338 ? 7.14594   -39.88308 17.24733  1.000 68.03337  ? 298 ASP C OD2 1 
ATOM   6981 N N   . ARG C 1 339 ? 5.34698   -37.77713 19.53582  1.000 52.50217  ? 299 ARG C N   1 
ATOM   6982 C CA  . ARG C 1 339 ? 5.35484   -36.36400 19.16484  1.000 56.41182  ? 299 ARG C CA  1 
ATOM   6983 C C   . ARG C 1 339 ? 5.80109   -36.16115 17.71995  1.000 55.32000  ? 299 ARG C C   1 
ATOM   6984 O O   . ARG C 1 339 ? 5.16459   -35.41874 16.96311  1.000 54.86117  ? 299 ARG C O   1 
ATOM   6985 C CB  . ARG C 1 339 ? 6.24558   -35.56845 20.12243  1.000 44.73163  ? 299 ARG C CB  1 
ATOM   6986 C CG  . ARG C 1 339 ? 6.41130   -34.10610 19.71535  1.000 55.84858  ? 299 ARG C CG  1 
ATOM   6987 C CD  . ARG C 1 339 ? 7.13267   -33.28041 20.77657  1.000 70.02830  ? 299 ARG C CD  1 
ATOM   6988 N NE  . ARG C 1 339 ? 6.25262   -32.88542 21.87041  1.000 67.11220  ? 299 ARG C NE  1 
ATOM   6989 C CZ  . ARG C 1 339 ? 5.79521   -31.65327 22.05137  1.000 75.07605  ? 299 ARG C CZ  1 
ATOM   6990 N NH1 . ARG C 1 339 ? 6.11073   -30.66988 21.22363  1.000 61.95735  ? 299 ARG C NH1 1 
ATOM   6991 N NH2 . ARG C 1 339 ? 4.99887   -31.40129 23.08665  1.000 81.55471  ? 299 ARG C NH2 1 
ATOM   6992 N N   . ASP C 1 340 ? 6.90033   -36.80493 17.31876  1.000 54.57534  ? 300 ASP C N   1 
ATOM   6993 C CA  . ASP C 1 340 ? 7.40450   -36.60556 15.96231  1.000 57.61780  ? 300 ASP C CA  1 
ATOM   6994 C C   . ASP C 1 340 ? 6.43550   -37.13941 14.91570  1.000 57.29501  ? 300 ASP C C   1 
ATOM   6995 O O   . ASP C 1 340 ? 6.26523   -36.52849 13.85384  1.000 58.34520  ? 300 ASP C O   1 
ATOM   6996 C CB  . ASP C 1 340 ? 8.77887   -37.25449 15.80315  1.000 56.03526  ? 300 ASP C CB  1 
ATOM   6997 C CG  . ASP C 1 340 ? 9.91054   -36.30482 16.14939  1.000 59.36664  ? 300 ASP C CG  1 
ATOM   6998 O OD1 . ASP C 1 340 ? 9.61968   -35.13549 16.47923  1.000 58.75149  ? 300 ASP C OD1 1 
ATOM   6999 O OD2 . ASP C 1 340 ? 11.08654  -36.71811 16.08147  1.000 56.09440  ? 300 ASP C OD2 1 
ATOM   7000 N N   . GLU C 1 341 ? 5.79316   -38.27596 15.18874  1.000 63.59942  ? 301 GLU C N   1 
ATOM   7001 C CA  . GLU C 1 341 ? 4.84164   -38.81111 14.22265  1.000 66.78727  ? 301 GLU C CA  1 
ATOM   7002 C C   . GLU C 1 341 ? 3.59212   -37.94555 14.13258  1.000 57.73917  ? 301 GLU C C   1 
ATOM   7003 O O   . GLU C 1 341 ? 3.00711   -37.81644 13.05109  1.000 59.15742  ? 301 GLU C O   1 
ATOM   7004 C CB  . GLU C 1 341 ? 4.47468   -40.25127 14.57559  1.000 60.18351  ? 301 GLU C CB  1 
ATOM   7005 C CG  . GLU C 1 341 ? 4.81638   -41.25822 13.48246  1.000 86.87909  ? 301 GLU C CG  1 
ATOM   7006 C CD  . GLU C 1 341 ? 4.18538   -40.92038 12.13820  1.000 99.87087  ? 301 GLU C CD  1 
ATOM   7007 O OE1 . GLU C 1 341 ? 3.05001   -40.40085 12.11271  1.000 78.28563  ? 301 GLU C OE1 1 
ATOM   7008 O OE2 . GLU C 1 341 ? 4.82839   -41.18124 11.10001  1.000 104.77462 ? 301 GLU C OE2 1 
ATOM   7009 N N   . LEU C 1 342 ? 3.17390   -37.33977 15.24715  1.000 51.55755  ? 302 LEU C N   1 
ATOM   7010 C CA  . LEU C 1 342 ? 2.04337   -36.41876 15.19691  1.000 59.74394  ? 302 LEU C CA  1 
ATOM   7011 C C   . LEU C 1 342 ? 2.37230   -35.19559 14.35218  1.000 55.72075  ? 302 LEU C C   1 
ATOM   7012 O O   . LEU C 1 342 ? 1.54648   -34.74745 13.54835  1.000 54.93127  ? 302 LEU C O   1 
ATOM   7013 C CB  . LEU C 1 342 ? 1.63468   -36.00155 16.61027  1.000 55.64017  ? 302 LEU C CB  1 
ATOM   7014 C CG  . LEU C 1 342 ? 0.94509   -37.05660 17.47630  1.000 61.50936  ? 302 LEU C CG  1 
ATOM   7015 C CD1 . LEU C 1 342 ? 0.82196   -36.57509 18.91657  1.000 57.11325  ? 302 LEU C CD1 1 
ATOM   7016 C CD2 . LEU C 1 342 ? -0.42416  -37.40408 16.90213  1.000 48.77615  ? 302 LEU C CD2 1 
ATOM   7017 N N   . ILE C 1 343 ? 3.57215   -34.63728 14.52613  1.000 47.85049  ? 303 ILE C N   1 
ATOM   7018 C CA  . ILE C 1 343 ? 3.98142   -33.48407 13.72897  1.000 54.33906  ? 303 ILE C CA  1 
ATOM   7019 C C   . ILE C 1 343 ? 4.09547   -33.86837 12.25903  1.000 50.77343  ? 303 ILE C C   1 
ATOM   7020 O O   . ILE C 1 343 ? 3.69658   -33.10855 11.36702  1.000 55.06960  ? 303 ILE C O   1 
ATOM   7021 C CB  . ILE C 1 343 ? 5.30213   -32.90682 14.27087  1.000 47.20974  ? 303 ILE C CB  1 
ATOM   7022 C CG1 . ILE C 1 343 ? 5.09706   -32.31749 15.66852  1.000 53.42474  ? 303 ILE C CG1 1 
ATOM   7023 C CG2 . ILE C 1 343 ? 5.86325   -31.85812 13.32661  1.000 48.68188  ? 303 ILE C CG2 1 
ATOM   7024 C CD1 . ILE C 1 343 ? 6.38851   -31.91359 16.35199  1.000 49.53222  ? 303 ILE C CD1 1 
ATOM   7025 N N   . ARG C 1 344 ? 4.65344   -35.04934 11.98437  1.000 50.62365  ? 304 ARG C N   1 
ATOM   7026 C CA  . ARG C 1 344 ? 4.76103   -35.52276 10.60792  1.000 56.79151  ? 304 ARG C CA  1 
ATOM   7027 C C   . ARG C 1 344 ? 3.38620   -35.71804 9.98128   1.000 53.87648  ? 304 ARG C C   1 
ATOM   7028 O O   . ARG C 1 344 ? 3.19577   -35.45385 8.78785   1.000 60.84466  ? 304 ARG C O   1 
ATOM   7029 C CB  . ARG C 1 344 ? 5.56614   -36.82215 10.56635  1.000 54.90309  ? 304 ARG C CB  1 
ATOM   7030 C CG  . ARG C 1 344 ? 5.72799   -37.42910 9.17898   1.000 52.12929  ? 304 ARG C CG  1 
ATOM   7031 C CD  . ARG C 1 344 ? 6.61011   -38.67072 9.23270   1.000 62.15994  ? 304 ARG C CD  1 
ATOM   7032 N NE  . ARG C 1 344 ? 7.93791   -38.36277 9.75238   1.000 76.04546  ? 304 ARG C NE  1 
ATOM   7033 C CZ  . ARG C 1 344 ? 8.38660   -38.74407 10.94094  1.000 74.78951  ? 304 ARG C CZ  1 
ATOM   7034 N NH1 . ARG C 1 344 ? 7.63957   -39.46086 11.76492  1.000 69.92015  ? 304 ARG C NH1 1 
ATOM   7035 N NH2 . ARG C 1 344 ? 9.61174   -38.38813 11.31667  1.000 68.75557  ? 304 ARG C NH2 1 
ATOM   7036 N N   . ARG C 1 345 ? 2.41313   -36.17700 10.77156  1.000 61.13578  ? 305 ARG C N   1 
ATOM   7037 C CA  . ARG C 1 345 ? 1.09837   -36.48894 10.22456  1.000 60.96560  ? 305 ARG C CA  1 
ATOM   7038 C C   . ARG C 1 345 ? 0.21631   -35.25593 10.08794  1.000 60.03347  ? 305 ARG C C   1 
ATOM   7039 O O   . ARG C 1 345 ? -0.65500  -35.21992 9.21159   1.000 63.64732  ? 305 ARG C O   1 
ATOM   7040 C CB  . ARG C 1 345 ? 0.36729   -37.49262 11.11748  1.000 53.10533  ? 305 ARG C CB  1 
ATOM   7041 C CG  . ARG C 1 345 ? -0.89317  -38.07353 10.48735  1.000 74.36830  ? 305 ARG C CG  1 
ATOM   7042 C CD  . ARG C 1 345 ? -1.88952  -38.51391 11.54524  1.000 73.34206  ? 305 ARG C CD  1 
ATOM   7043 N NE  . ARG C 1 345 ? -1.27906  -39.28249 12.62125  1.000 66.68486  ? 305 ARG C NE  1 
ATOM   7044 C CZ  . ARG C 1 345 ? -1.84076  -39.46529 13.80809  1.000 65.19805  ? 305 ARG C CZ  1 
ATOM   7045 N NH1 . ARG C 1 345 ? -3.02358  -38.94888 14.09799  1.000 55.46475  ? 305 ARG C NH1 1 
ATOM   7046 N NH2 . ARG C 1 345 ? -1.19828  -40.17869 14.72840  1.000 79.75940  ? 305 ARG C NH2 1 
ATOM   7047 N N   . LEU C 1 346 ? 0.42982   -34.23724 10.91732  1.000 48.71392  ? 306 LEU C N   1 
ATOM   7048 C CA  . LEU C 1 346 ? -0.55754  -33.17972 11.07668  1.000 52.00619  ? 306 LEU C CA  1 
ATOM   7049 C C   . LEU C 1 346 ? -0.08044  -31.79486 10.67060  1.000 62.38385  ? 306 LEU C C   1 
ATOM   7050 O O   . LEU C 1 346 ? -0.90331  -30.98748 10.23072  1.000 52.77239  ? 306 LEU C O   1 
ATOM   7051 C CB  . LEU C 1 346 ? -1.03483  -33.12833 12.53531  1.000 50.78322  ? 306 LEU C CB  1 
ATOM   7052 C CG  . LEU C 1 346 ? -1.82970  -34.36229 12.95841  1.000 58.11153  ? 306 LEU C CG  1 
ATOM   7053 C CD1 . LEU C 1 346 ? -2.07526  -34.36105 14.45684  1.000 47.60230  ? 306 LEU C CD1 1 
ATOM   7054 C CD2 . LEU C 1 346 ? -3.13366  -34.41916 12.18874  1.000 54.81027  ? 306 LEU C CD2 1 
ATOM   7055 N N   . VAL C 1 347 ? 1.20558   -31.48874 10.80585  1.000 49.61181  ? 307 VAL C N   1 
ATOM   7056 C CA  . VAL C 1 347 ? 1.68111   -30.15176 10.47669  1.000 50.06679  ? 307 VAL C CA  1 
ATOM   7057 C C   . VAL C 1 347 ? 1.96847   -30.06884 8.98366   1.000 60.66933  ? 307 VAL C C   1 
ATOM   7058 O O   . VAL C 1 347 ? 1.36211   -29.27400 8.26298   1.000 56.99487  ? 307 VAL C O   1 
ATOM   7059 C CB  . VAL C 1 347 ? 2.92677   -29.77365 11.29286  1.000 45.55687  ? 307 VAL C CB  1 
ATOM   7060 C CG1 . VAL C 1 347 ? 3.45816   -28.42403 10.84611  1.000 43.58281  ? 307 VAL C CG1 1 
ATOM   7061 C CG2 . VAL C 1 347 ? 2.60664   -29.75929 12.77908  1.000 42.99890  ? 307 VAL C CG2 1 
ATOM   7062 O OXT . VAL C 1 347 ? 2.80161   -30.81031 8.46063   1.000 56.14376  ? 307 VAL C OXT 1 
HETATM 7063 P PA  . NAP D 2 .   ? 8.90349   -14.46113 -3.33480  1.000 64.70141  ? 401 NAP A PA  1 
HETATM 7064 O O1A . NAP D 2 .   ? 7.93820   -13.42235 -3.76694  1.000 74.44771  ? 401 NAP A O1A 1 
HETATM 7065 O O2A . NAP D 2 .   ? 9.57027   -15.10864 -4.48549  1.000 65.00755  ? 401 NAP A O2A 1 
HETATM 7066 O O5B . NAP D 2 .   ? 9.98842   -13.81452 -2.34453  1.000 73.48984  ? 401 NAP A O5B 1 
HETATM 7067 C C5B . NAP D 2 .   ? 11.26133  -14.39616 -2.19221  1.000 63.89207  ? 401 NAP A C5B 1 
HETATM 7068 C C4B . NAP D 2 .   ? 12.15843  -13.33472 -1.57700  1.000 65.98078  ? 401 NAP A C4B 1 
HETATM 7069 O O4B . NAP D 2 .   ? 13.22946  -13.92868 -0.87233  1.000 67.77779  ? 401 NAP A O4B 1 
HETATM 7070 C C3B . NAP D 2 .   ? 12.77142  -12.44757 -2.64351  1.000 58.28677  ? 401 NAP A C3B 1 
HETATM 7071 O O3B . NAP D 2 .   ? 12.02452  -11.26325 -2.78303  1.000 62.90602  ? 401 NAP A O3B 1 
HETATM 7072 C C2B . NAP D 2 .   ? 14.14734  -12.13046 -2.10827  1.000 65.58475  ? 401 NAP A C2B 1 
HETATM 7073 O O2B . NAP D 2 .   ? 14.03949  -10.92002 -1.40733  1.000 72.50111  ? 401 NAP A O2B 1 
HETATM 7074 C C1B . NAP D 2 .   ? 14.45231  -13.28020 -1.16274  1.000 58.63294  ? 401 NAP A C1B 1 
HETATM 7075 N N9A . NAP D 2 .   ? 15.35936  -14.23303 -1.82766  1.000 63.13609  ? 401 NAP A N9A 1 
HETATM 7076 C C8A . NAP D 2 .   ? 15.17419  -14.78831 -3.06831  1.000 62.22156  ? 401 NAP A C8A 1 
HETATM 7077 N N7A . NAP D 2 .   ? 16.21038  -15.61237 -3.33272  1.000 67.71410  ? 401 NAP A N7A 1 
HETATM 7078 C C5A . NAP D 2 .   ? 17.05354  -15.59821 -2.27841  1.000 68.41171  ? 401 NAP A C5A 1 
HETATM 7079 C C6A . NAP D 2 .   ? 18.25082  -16.25876 -2.03734  1.000 77.70486  ? 401 NAP A C6A 1 
HETATM 7080 N N6A . NAP D 2 .   ? 18.75168  -17.08549 -2.95345  1.000 72.15609  ? 401 NAP A N6A 1 
HETATM 7081 N N1A . NAP D 2 .   ? 18.91356  -16.05046 -0.84400  1.000 84.71836  ? 401 NAP A N1A 1 
HETATM 7082 C C2A . NAP D 2 .   ? 18.38081  -15.18901 0.09627   1.000 70.69533  ? 401 NAP A C2A 1 
HETATM 7083 N N3A . NAP D 2 .   ? 17.18856  -14.53565 -0.15304  1.000 64.96144  ? 401 NAP A N3A 1 
HETATM 7084 C C4A . NAP D 2 .   ? 16.53448  -14.73408 -1.32387  1.000 65.64447  ? 401 NAP A C4A 1 
HETATM 7085 O O3  . NAP D 2 .   ? 8.16247   -15.54933 -2.41033  1.000 64.63973  ? 401 NAP A O3  1 
HETATM 7086 P PN  . NAP D 2 .   ? 6.92490   -15.40262 -1.39179  1.000 65.67502  ? 401 NAP A PN  1 
HETATM 7087 O O1N . NAP D 2 .   ? 5.65932   -15.50613 -2.15258  1.000 74.58203  ? 401 NAP A O1N 1 
HETATM 7088 O O2N . NAP D 2 .   ? 7.17877   -14.22863 -0.52965  1.000 67.40274  ? 401 NAP A O2N 1 
HETATM 7089 O O5D . NAP D 2 .   ? 7.09117   -16.72730 -0.49629  1.000 70.87053  ? 401 NAP A O5D 1 
HETATM 7090 C C5D . NAP D 2 .   ? 8.22364   -16.86260 0.32982   1.000 61.65940  ? 401 NAP A C5D 1 
HETATM 7091 C C4D . NAP D 2 .   ? 8.18436   -18.17888 1.09579   1.000 60.49321  ? 401 NAP A C4D 1 
HETATM 7092 O O4D . NAP D 2 .   ? 7.06155   -18.25230 1.95251   1.000 62.12394  ? 401 NAP A O4D 1 
HETATM 7093 C C3D . NAP D 2 .   ? 8.07435   -19.36448 0.15076   1.000 53.71855  ? 401 NAP A C3D 1 
HETATM 7094 O O3D . NAP D 2 .   ? 9.34115   -19.92756 -0.09615  1.000 75.69942  ? 401 NAP A O3D 1 
HETATM 7095 C C2D . NAP D 2 .   ? 7.18863   -20.35875 0.87150   1.000 64.59382  ? 401 NAP A C2D 1 
HETATM 7096 O O2D . NAP D 2 .   ? 7.94999   -21.44681 1.33736   1.000 68.95793  ? 401 NAP A O2D 1 
HETATM 7097 C C1D . NAP D 2 .   ? 6.60734   -19.59112 2.04848   1.000 68.87219  ? 401 NAP A C1D 1 
HETATM 7098 N N1N . NAP D 2 .   ? 5.13456   -19.67941 2.03745   1.000 72.96253  ? 401 NAP A N1N 1 
HETATM 7099 C C2N . NAP D 2 .   ? 4.52415   -20.57429 2.86732   1.000 62.80426  ? 401 NAP A C2N 1 
HETATM 7100 C C3N . NAP D 2 .   ? 3.14071   -20.69431 2.88828   1.000 71.87268  ? 401 NAP A C3N 1 
HETATM 7101 C C7N . NAP D 2 .   ? 2.48433   -21.44404 4.01080   1.000 63.21161  ? 401 NAP A C7N 1 
HETATM 7102 O O7N . NAP D 2 .   ? 1.08495   -21.61177 4.00194   1.000 65.36575  ? 401 NAP A O7N 1 
HETATM 7103 N N7N . NAP D 2 .   ? 3.24333   -21.93125 4.99204   1.000 62.24388  ? 401 NAP A N7N 1 
HETATM 7104 C C4N . NAP D 2 .   ? 2.37572   -19.88974 2.05165   1.000 64.37270  ? 401 NAP A C4N 1 
HETATM 7105 C C5N . NAP D 2 .   ? 3.00416   -18.98092 1.20822   1.000 60.76750  ? 401 NAP A C5N 1 
HETATM 7106 C C6N . NAP D 2 .   ? 4.39125   -18.88452 1.21156   1.000 69.07836  ? 401 NAP A C6N 1 
HETATM 7107 P P2B . NAP D 2 .   ? 15.12754  -9.75822  -1.61646  1.000 65.74279  ? 401 NAP A P2B 1 
HETATM 7108 O O1X . NAP D 2 .   ? 14.79955  -8.61451  -0.68767  1.000 57.94162  ? 401 NAP A O1X 1 
HETATM 7109 O O2X . NAP D 2 .   ? 15.03553  -9.26978  -3.04312  1.000 70.60324  ? 401 NAP A O2X 1 
HETATM 7110 O O3X . NAP D 2 .   ? 16.50589  -10.29929 -1.32536  1.000 57.92812  ? 401 NAP A O3X 1 
HETATM 7111 C C1  . OXM E 3 .   ? 0.32168   -22.51331 -0.65449  1.000 95.81116  ? 402 OXM A C1  1 
HETATM 7112 N N1  . OXM E 3 .   ? 0.20561   -22.46988 0.66151   1.000 80.25766  ? 402 OXM A N1  1 
HETATM 7113 O O1  . OXM E 3 .   ? 0.73860   -21.55098 -1.33272  1.000 90.86548  ? 402 OXM A O1  1 
HETATM 7114 C C2  . OXM E 3 .   ? -0.04742  -23.76357 -1.35615  1.000 97.26633  ? 402 OXM A C2  1 
HETATM 7115 O O2  . OXM E 3 .   ? -0.73872  -24.61578 -0.75946  1.000 82.21482  ? 402 OXM A O2  1 
HETATM 7116 O O3  . OXM E 3 .   ? 0.33182   -23.93125 -2.53490  1.000 94.85897  ? 402 OXM A O3  1 
HETATM 7117 N N1  . IMD F 4 .   ? -0.76548  -32.44380 3.61697   1.000 83.08976  ? 403 IMD A N1  1 
HETATM 7118 C C2  . IMD F 4 .   ? -2.01263  -32.45647 3.09310   1.000 92.20326  ? 403 IMD A C2  1 
HETATM 7119 N N3  . IMD F 4 .   ? -2.38169  -31.18577 2.81451   1.000 86.31453  ? 403 IMD A N3  1 
HETATM 7120 C C4  . IMD F 4 .   ? -1.36586  -30.36697 3.16232   1.000 71.08337  ? 403 IMD A C4  1 
HETATM 7121 C C5  . IMD F 4 .   ? -0.34507  -31.16250 3.66842   1.000 74.49841  ? 403 IMD A C5  1 
HETATM 7122 C C   . ACY G 5 .   ? -1.56648  -30.13119 -1.21447  1.000 83.06387  ? 404 ACY A C   1 
HETATM 7123 O O   . ACY G 5 .   ? -2.63975  -30.51265 -0.66190  1.000 82.13833  ? 404 ACY A O   1 
HETATM 7124 O OXT . ACY G 5 .   ? -0.48467  -29.76716 -0.67266  1.000 86.69963  ? 404 ACY A OXT 1 
HETATM 7125 C CH3 . ACY G 5 .   ? -1.55830  -30.09962 -2.78059  1.000 59.26333  ? 404 ACY A CH3 1 
HETATM 7126 P PA  . NAP H 2 .   ? 19.88072  -56.31263 38.70562  1.000 64.12405  ? 401 NAP B PA  1 
HETATM 7127 O O1A . NAP H 2 .   ? 20.84589  -56.87654 39.67301  1.000 70.78304  ? 401 NAP B O1A 1 
HETATM 7128 O O2A . NAP H 2 .   ? 19.09949  -57.37211 38.03050  1.000 59.25274  ? 401 NAP B O2A 1 
HETATM 7129 O O5B . NAP H 2 .   ? 18.88703  -55.29732 39.44930  1.000 65.96533  ? 401 NAP B O5B 1 
HETATM 7130 C C5B . NAP H 2 .   ? 17.59876  -55.05648 38.94131  1.000 65.01926  ? 401 NAP B C5B 1 
HETATM 7131 C C4B . NAP H 2 .   ? 16.77566  -54.42118 40.05022  1.000 66.49501  ? 401 NAP B C4B 1 
HETATM 7132 O O4B . NAP H 2 .   ? 15.71519  -53.67403 39.49174  1.000 63.45338  ? 401 NAP B O4B 1 
HETATM 7133 C C3B . NAP H 2 .   ? 16.16193  -55.45778 40.97537  1.000 76.76624  ? 401 NAP B C3B 1 
HETATM 7134 O O3B . NAP H 2 .   ? 16.94983  -55.60083 42.13145  1.000 66.49163  ? 401 NAP B O3B 1 
HETATM 7135 C C2B . NAP H 2 .   ? 14.81730  -54.87248 41.33368  1.000 71.33133  ? 401 NAP B C2B 1 
HETATM 7136 O O2B . NAP H 2 .   ? 14.97951  -54.14655 42.52482  1.000 65.67437  ? 401 NAP B O2B 1 
HETATM 7137 C C1B . NAP H 2 .   ? 14.51190  -53.92083 40.18961  1.000 70.64085  ? 401 NAP B C1B 1 
HETATM 7138 N N9A . NAP H 2 .   ? 13.55985  -54.55152 39.26202  1.000 72.96507  ? 401 NAP B N9A 1 
HETATM 7139 C C8A . NAP H 2 .   ? 13.69972  -55.77921 38.66694  1.000 67.70546  ? 401 NAP B C8A 1 
HETATM 7140 N N7A . NAP H 2 .   ? 12.62223  -55.99734 37.88329  1.000 73.84073  ? 401 NAP B N7A 1 
HETATM 7141 C C5A . NAP H 2 .   ? 11.80093  -54.92687 37.96235  1.000 78.49466  ? 401 NAP B C5A 1 
HETATM 7142 C C6A . NAP H 2 .   ? 10.58021  -54.63611 37.36517  1.000 84.06912  ? 401 NAP B C6A 1 
HETATM 7143 N N6A . NAP H 2 .   ? 10.01547  -55.51069 36.53576  1.000 78.37099  ? 401 NAP B N6A 1 
HETATM 7144 N N1A . NAP H 2 .   ? 9.95809   -53.43377 37.63930  1.000 88.63956  ? 401 NAP B N1A 1 
HETATM 7145 C C2A . NAP H 2 .   ? 10.55065  -52.53093 38.50214  1.000 87.07584  ? 401 NAP B C2A 1 
HETATM 7146 N N3A . NAP H 2 .   ? 11.76460  -52.82905 39.09056  1.000 76.54370  ? 401 NAP B N3A 1 
HETATM 7147 C C4A . NAP H 2 .   ? 12.37789  -54.00901 38.82777  1.000 66.10374  ? 401 NAP B C4A 1 
HETATM 7148 O O3  . NAP H 2 .   ? 20.64351  -55.37641 37.64257  1.000 74.11102  ? 401 NAP B O3  1 
HETATM 7149 P PN  . NAP H 2 .   ? 21.95101  -54.45442 37.83417  1.000 69.15536  ? 401 NAP B PN  1 
HETATM 7150 O O1N . NAP H 2 .   ? 23.15334  -55.30254 37.70352  1.000 79.08355  ? 401 NAP B O1N 1 
HETATM 7151 O O2N . NAP H 2 .   ? 21.74151  -53.63769 39.05051  1.000 60.98132  ? 401 NAP B O2N 1 
HETATM 7152 O O5D . NAP H 2 .   ? 21.88116  -53.46446 36.56599  1.000 69.78288  ? 401 NAP B O5D 1 
HETATM 7153 C C5D . NAP H 2 .   ? 20.63090  -53.11901 36.01717  1.000 61.35284  ? 401 NAP B C5D 1 
HETATM 7154 C C4D . NAP H 2 .   ? 20.77376  -52.16291 34.84262  1.000 66.30009  ? 401 NAP B C4D 1 
HETATM 7155 O O4D . NAP H 2 .   ? 21.97289  -51.41075 34.88113  1.000 75.81607  ? 401 NAP B O4D 1 
HETATM 7156 C C3D . NAP H 2 .   ? 20.80615  -52.93966 33.53999  1.000 74.84045  ? 401 NAP B C3D 1 
HETATM 7157 O O3D . NAP H 2 .   ? 19.53242  -52.98344 32.93941  1.000 76.42350  ? 401 NAP B O3D 1 
HETATM 7158 C C2D . NAP H 2 .   ? 21.76279  -52.18296 32.64695  1.000 73.88059  ? 401 NAP B C2D 1 
HETATM 7159 O O2D . NAP H 2 .   ? 21.04232  -51.52217 31.63277  1.000 67.30400  ? 401 NAP B O2D 1 
HETATM 7160 C C1D . NAP H 2 .   ? 22.44332  -51.17019 33.56083  1.000 65.78799  ? 401 NAP B C1D 1 
HETATM 7161 N N1N . NAP H 2 .   ? 23.91184  -51.26864 33.43769  1.000 61.71352  ? 401 NAP B N1N 1 
HETATM 7162 C C2N . NAP H 2 .   ? 24.55277  -50.36774 32.63706  1.000 66.80825  ? 401 NAP B C2N 1 
HETATM 7163 C C3N . NAP H 2 .   ? 25.93070  -50.41211 32.47737  1.000 70.83697  ? 401 NAP B C3N 1 
HETATM 7164 C C7N . NAP H 2 .   ? 26.61244  -49.39922 31.60291  1.000 68.73109  ? 401 NAP B C7N 1 
HETATM 7165 O O7N . NAP H 2 .   ? 25.87901  -48.29461 31.12066  1.000 67.58912  ? 401 NAP B O7N 1 
HETATM 7166 N N7N . NAP H 2 .   ? 27.90007  -49.56852 31.31018  1.000 73.36321  ? 401 NAP B N7N 1 
HETATM 7167 C C4N . NAP H 2 .   ? 26.66195  -51.39319 33.13989  1.000 64.69727  ? 401 NAP B C4N 1 
HETATM 7168 C C5N . NAP H 2 .   ? 26.00115  -52.30835 33.95321  1.000 62.56456  ? 401 NAP B C5N 1 
HETATM 7169 C C6N . NAP H 2 .   ? 24.61908  -52.23537 34.09748  1.000 68.13128  ? 401 NAP B C6N 1 
HETATM 7170 P P2B . NAP H 2 .   ? 13.91561  -54.29491 43.72122  1.000 70.89000  ? 401 NAP B P2B 1 
HETATM 7171 O O1X . NAP H 2 .   ? 14.51795  -53.67593 44.96128  1.000 59.62648  ? 401 NAP B O1X 1 
HETATM 7172 O O2X . NAP H 2 .   ? 12.63908  -53.57767 43.35236  1.000 60.37816  ? 401 NAP B O2X 1 
HETATM 7173 O O3X . NAP H 2 .   ? 13.63979  -55.75849 43.95935  1.000 82.55086  ? 401 NAP B O3X 1 
HETATM 7174 C C1  . OXM I 3 .   ? 29.20728  -53.42848 29.82257  1.000 87.39352  ? 402 OXM B C1  1 
HETATM 7175 N N1  . OXM I 3 .   ? 29.01785  -52.61746 30.84724  1.000 75.66633  ? 402 OXM B N1  1 
HETATM 7176 O O1  . OXM I 3 .   ? 29.41251  -53.01931 28.65970  1.000 85.48241  ? 402 OXM B O1  1 
HETATM 7177 C C2  . OXM I 3 .   ? 29.18066  -54.88570 30.07747  1.000 84.30867  ? 402 OXM B C2  1 
HETATM 7178 O O2  . OXM I 3 .   ? 28.71123  -55.29341 31.15967  1.000 84.18124  ? 402 OXM B O2  1 
HETATM 7179 O O3  . OXM I 3 .   ? 29.61359  -55.67134 29.20620  1.000 73.57489  ? 402 OXM B O3  1 
HETATM 7180 N N1  . IMD J 4 .   ? 30.98271  -27.43815 38.05913  1.000 63.64603  ? 403 IMD B N1  1 
HETATM 7181 C C2  . IMD J 4 .   ? 31.61123  -27.94359 39.14275  1.000 65.20521  ? 403 IMD B C2  1 
HETATM 7182 N N3  . IMD J 4 .   ? 31.44732  -27.10793 40.18974  1.000 58.90896  ? 403 IMD B N3  1 
HETATM 7183 C C4  . IMD J 4 .   ? 30.70385  -26.06717 39.76534  1.000 69.11890  ? 403 IMD B C4  1 
HETATM 7184 C C5  . IMD J 4 .   ? 30.41124  -26.27492 38.42220  1.000 61.71034  ? 403 IMD B C5  1 
HETATM 7185 N N1  . IMD K 4 .   ? 34.99754  -47.53649 11.57108  1.000 81.50961  ? 404 IMD B N1  1 
HETATM 7186 C C2  . IMD K 4 .   ? 35.26531  -48.70090 12.20382  1.000 84.90719  ? 404 IMD B C2  1 
HETATM 7187 N N3  . IMD K 4 .   ? 34.17974  -49.50128 12.11488  1.000 98.69806  ? 404 IMD B N3  1 
HETATM 7188 C C4  . IMD K 4 .   ? 33.22348  -48.84337 11.42488  1.000 89.40704  ? 404 IMD B C4  1 
HETATM 7189 C C5  . IMD K 4 .   ? 33.74111  -47.60106 11.08094  1.000 86.03868  ? 404 IMD B C5  1 
HETATM 7190 N N1  . IMD L 4 .   ? 29.31928  -49.06743 20.62697  1.000 82.45993  ? 405 IMD B N1  1 
HETATM 7191 C C2  . IMD L 4 .   ? 29.81125  -49.23344 21.87546  1.000 82.51440  ? 405 IMD B C2  1 
HETATM 7192 N N3  . IMD L 4 .   ? 30.80375  -50.15163 21.83658  1.000 82.64659  ? 405 IMD B N3  1 
HETATM 7193 C C4  . IMD L 4 .   ? 30.94272  -50.57002 20.56063  1.000 86.67591  ? 405 IMD B C4  1 
HETATM 7194 C C5  . IMD L 4 .   ? 30.00456  -49.88434 19.79851  1.000 99.39267  ? 405 IMD B C5  1 
HETATM 7195 C C   . ACY M 5 .   ? 35.14110  -63.33873 35.18647  1.000 78.03455  ? 406 ACY B C   1 
HETATM 7196 O O   . ACY M 5 .   ? 34.03653  -63.77980 35.63467  1.000 60.18260  ? 406 ACY B O   1 
HETATM 7197 O OXT . ACY M 5 .   ? 36.31257  -63.46038 35.67596  1.000 63.72249  ? 406 ACY B OXT 1 
HETATM 7198 C CH3 . ACY M 5 .   ? 35.06647  -62.52993 33.84148  1.000 61.98603  ? 406 ACY B CH3 1 
HETATM 7199 N N1  . IMD N 4 .   ? 35.08549  -51.72852 18.44503  1.000 74.05924  ? 407 IMD B N1  1 
HETATM 7200 C C2  . IMD N 4 .   ? 33.86586  -52.20036 18.10225  1.000 86.97491  ? 407 IMD B C2  1 
HETATM 7201 N N3  . IMD N 4 .   ? 33.49932  -51.63472 16.92839  1.000 99.15821  ? 407 IMD B N3  1 
HETATM 7202 C C4  . IMD N 4 .   ? 34.48798  -50.80565 16.52956  1.000 79.88015  ? 407 IMD B C4  1 
HETATM 7203 C C5  . IMD N 4 .   ? 35.49128  -50.86481 17.48850  1.000 58.80503  ? 407 IMD B C5  1 
HETATM 7204 P PA  . NAP O 2 .   ? -26.92376 -34.22418 34.04551  1.000 81.29445  ? 401 NAP C PA  1 
HETATM 7205 O O1A . NAP O 2 .   ? -27.55947 -35.24147 33.18367  1.000 82.48801  ? 401 NAP C O1A 1 
HETATM 7206 O O2A . NAP O 2 .   ? -27.95377 -33.45522 34.77861  1.000 83.74407  ? 401 NAP C O2A 1 
HETATM 7207 O O5B . NAP O 2 .   ? -25.92435 -34.97666 35.05309  1.000 69.03480  ? 401 NAP C O5B 1 
HETATM 7208 C C5B . NAP O 2 .   ? -25.55232 -34.44874 36.30474  1.000 74.85891  ? 401 NAP C C5B 1 
HETATM 7209 C C4B . NAP O 2 .   ? -24.99489 -35.61751 37.10404  1.000 71.59340  ? 401 NAP C C4B 1 
HETATM 7210 O O4B . NAP O 2 .   ? -24.07239 -35.20350 38.09326  1.000 81.73542  ? 401 NAP C O4B 1 
HETATM 7211 C C3B . NAP O 2 .   ? -26.09816 -36.36811 37.82781  1.000 73.23865  ? 401 NAP C C3B 1 
HETATM 7212 O O3B . NAP O 2 .   ? -26.49650 -37.48314 37.06799  1.000 71.92339  ? 401 NAP C O3B 1 
HETATM 7213 C C2B . NAP O 2 .   ? -25.45616 -36.83065 39.11151  1.000 74.44850  ? 401 NAP C C2B 1 
HETATM 7214 O O2B . NAP O 2 .   ? -24.97685 -38.11812 38.82586  1.000 65.72221  ? 401 NAP C O2B 1 
HETATM 7215 C C1B . NAP O 2 .   ? -24.29177 -35.87635 39.32060  1.000 76.39690  ? 401 NAP C C1B 1 
HETATM 7216 N N9A . NAP O 2 .   ? -24.56418 -34.90032 40.40210  1.000 80.69659  ? 401 NAP C N9A 1 
HETATM 7217 C C8A . NAP O 2 .   ? -23.64999 -34.53967 41.35848  1.000 86.31276  ? 401 NAP C C8A 1 
HETATM 7218 N N7A . NAP O 2 .   ? -24.21460 -33.63881 42.18988  1.000 78.47113  ? 401 NAP C N7A 1 
HETATM 7219 C C5A . NAP O 2 .   ? -25.47971 -33.40615 41.78222  1.000 85.36732  ? 401 NAP C C5A 1 
HETATM 7220 C C6A . NAP O 2 .   ? -26.47361 -32.57348 42.28286  1.000 90.99111  ? 401 NAP C C6A 1 
HETATM 7221 N N6A . NAP O 2 .   ? -26.24340 -31.82310 43.35788  1.000 88.47022  ? 401 NAP C N6A 1 
HETATM 7222 N N1A . NAP O 2 .   ? -27.70177 -32.52929 41.65862  1.000 92.47119  ? 401 NAP C N1A 1 
HETATM 7223 C C2A . NAP O 2 .   ? -27.92948 -33.31083 40.54356  1.000 84.33052  ? 401 NAP C C2A 1 
HETATM 7224 N N3A . NAP O 2 .   ? -26.93514 -34.13481 40.05471  1.000 74.09699  ? 401 NAP C N3A 1 
HETATM 7225 C C4A . NAP O 2 .   ? -25.72389 -34.19464 40.66274  1.000 77.21650  ? 401 NAP C C4A 1 
HETATM 7226 O O3  . NAP O 2 .   ? -25.95393 -33.25198 33.19641  1.000 81.16212  ? 401 NAP C O3  1 
HETATM 7227 P PN  . NAP O 2 .   ? -25.05080 -33.50495 31.88559  1.000 76.33848  ? 401 NAP C PN  1 
HETATM 7228 O O1N . NAP O 2 .   ? -25.88809 -33.23789 30.69361  1.000 56.36466  ? 401 NAP C O1N 1 
HETATM 7229 O O2N . NAP O 2 .   ? -24.33815 -34.79171 32.03771  1.000 78.79552  ? 401 NAP C O2N 1 
HETATM 7230 O O5D . NAP O 2 .   ? -24.02623 -32.26587 31.91544  1.000 74.41422  ? 401 NAP C O5D 1 
HETATM 7231 C C5D . NAP O 2 .   ? -23.91816 -31.50580 33.09957  1.000 79.55063  ? 401 NAP C C5D 1 
HETATM 7232 C C4D . NAP O 2 .   ? -22.84961 -30.42519 32.96812  1.000 74.73956  ? 401 NAP C C4D 1 
HETATM 7233 O O4D . NAP O 2 .   ? -22.10466 -30.57108 31.77082  1.000 74.29447  ? 401 NAP C O4D 1 
HETATM 7234 C C3D . NAP O 2 .   ? -23.40644 -29.01674 32.96035  1.000 73.11417  ? 401 NAP C C3D 1 
HETATM 7235 O O3D . NAP O 2 .   ? -23.35020 -28.47481 34.26022  1.000 82.81907  ? 401 NAP C O3D 1 
HETATM 7236 C C2D . NAP O 2 .   ? -22.49522 -28.24483 32.03243  1.000 79.33385  ? 401 NAP C C2D 1 
HETATM 7237 O O2D . NAP O 2 .   ? -21.66146 -27.40365 32.79566  1.000 69.60335  ? 401 NAP C O2D 1 
HETATM 7238 C C1D . NAP O 2 .   ? -21.65973 -29.30013 31.32084  1.000 69.87358  ? 401 NAP C C1D 1 
HETATM 7239 N N1N . NAP O 2 .   ? -21.77929 -29.15160 29.85662  1.000 73.27499  ? 401 NAP C N1N 1 
HETATM 7240 C C2N . NAP O 2 .   ? -20.77997 -28.52354 29.16951  1.000 71.28898  ? 401 NAP C C2N 1 
HETATM 7241 C C3N . NAP O 2 .   ? -20.85434 -28.36132 27.79255  1.000 72.70714  ? 401 NAP C C3N 1 
HETATM 7242 C C7N . NAP O 2 .   ? -19.83174 -27.52787 27.07681  1.000 67.25009  ? 401 NAP C C7N 1 
HETATM 7243 O O7N . NAP O 2 .   ? -19.85630 -27.47184 25.66792  1.000 66.74908  ? 401 NAP C O7N 1 
HETATM 7244 N N7N . NAP O 2 .   ? -18.92520 -26.86335 27.79233  1.000 63.53522  ? 401 NAP C N7N 1 
HETATM 7245 C C4N . NAP O 2 .   ? -21.96328 -28.84307 27.10988  1.000 78.41129  ? 401 NAP C C4N 1 
HETATM 7246 C C5N . NAP O 2 .   ? -22.97781 -29.47885 27.81699  1.000 82.54749  ? 401 NAP C C5N 1 
HETATM 7247 C C6N . NAP O 2 .   ? -22.87485 -29.63085 29.19618  1.000 76.83942  ? 401 NAP C C6N 1 
HETATM 7248 P P2B . NAP O 2 .   ? -25.09974 -39.33074 39.87366  1.000 78.75970  ? 401 NAP C P2B 1 
HETATM 7249 O O1X . NAP O 2 .   ? -25.43342 -38.81881 41.25476  1.000 90.43820  ? 401 NAP C O1X 1 
HETATM 7250 O O2X . NAP O 2 .   ? -26.11331 -40.33782 39.38567  1.000 92.96019  ? 401 NAP C O2X 1 
HETATM 7251 O O3X . NAP O 2 .   ? -23.75048 -40.00425 39.89129  1.000 78.95849  ? 401 NAP C O3X 1 
HETATM 7252 C C1  . OXM P 3 .   ? -24.38397 -26.20573 24.80176  1.000 98.56009  ? 402 OXM C C1  1 
HETATM 7253 N N1  . OXM P 3 .   ? -23.07467 -26.05037 24.73104  1.000 81.02435  ? 402 OXM C N1  1 
HETATM 7254 O O1  . OXM P 3 .   ? -24.92233 -27.28123 25.14215  1.000 95.17037  ? 402 OXM C O1  1 
HETATM 7255 C C2  . OXM P 3 .   ? -25.23991 -25.04650 24.46144  1.000 101.53379 ? 402 OXM C C2  1 
HETATM 7256 O O2  . OXM P 3 .   ? -26.47644 -25.20369 24.35972  1.000 97.29333  ? 402 OXM C O2  1 
HETATM 7257 O O3  . OXM P 3 .   ? -24.70059 -23.93430 24.28392  1.000 94.19352  ? 402 OXM C O3  1 
HETATM 7258 C C1  . OXM Q 3 .   ? -20.80348 -16.95354 22.97797  1.000 78.96306  ? 403 OXM C C1  1 
HETATM 7259 N N1  . OXM Q 3 .   ? -20.88934 -18.14622 22.41775  1.000 56.64873  ? 403 OXM C N1  1 
HETATM 7260 O O1  . OXM Q 3 .   ? -21.53038 -15.99174 22.65331  1.000 84.21322  ? 403 OXM C O1  1 
HETATM 7261 C C2  . OXM Q 3 .   ? -19.79293 -16.75483 24.03924  1.000 88.54945  ? 403 OXM C C2  1 
HETATM 7262 O O2  . OXM Q 3 .   ? -19.57680 -15.60124 24.46863  1.000 88.02888  ? 403 OXM C O2  1 
HETATM 7263 O O3  . OXM Q 3 .   ? -19.17901 -17.74874 24.47832  1.000 81.82105  ? 403 OXM C O3  1 
HETATM 7264 N N1  . IMD R 4 .   ? 1.71179   -34.96518 22.70351  1.000 62.68205  ? 404 IMD C N1  1 
HETATM 7265 C C2  . IMD R 4 .   ? 2.94624   -34.53357 23.04677  1.000 71.83956  ? 404 IMD C C2  1 
HETATM 7266 N N3  . IMD R 4 .   ? 3.83014   -35.53118 22.82479  1.000 71.15127  ? 404 IMD C N3  1 
HETATM 7267 C C4  . IMD R 4 .   ? 3.15608   -36.59484 22.34116  1.000 62.10315  ? 404 IMD C C4  1 
HETATM 7268 C C5  . IMD R 4 .   ? 1.81693   -36.23633 22.26365  1.000 62.23087  ? 404 IMD C C5  1 
HETATM 7269 O O   . HOH S 6 .   ? -7.90440  -34.44353 11.15612  1.000 53.02284  ? 501 HOH A O   1 
HETATM 7270 O O   . HOH S 6 .   ? 5.04016   -11.74521 22.75280  1.000 50.47252  ? 502 HOH A O   1 
HETATM 7271 O O   . HOH S 6 .   ? -1.08630  -24.78784 19.95120  1.000 44.72154  ? 503 HOH A O   1 
HETATM 7272 O O   . HOH S 6 .   ? 2.37664   -9.13457  -3.55807  1.000 51.47267  ? 504 HOH A O   1 
HETATM 7273 O O   . HOH S 6 .   ? 12.30014  -20.01486 12.70207  1.000 49.91913  ? 505 HOH A O   1 
HETATM 7274 O O   . HOH S 6 .   ? -9.50431  -31.71042 -2.91213  1.000 52.58031  ? 506 HOH A O   1 
HETATM 7275 O O   . HOH S 6 .   ? 3.91709   -24.85858 12.83232  1.000 43.70299  ? 507 HOH A O   1 
HETATM 7276 O O   . HOH S 6 .   ? 3.48506   -8.99140  23.08850  1.000 61.08301  ? 508 HOH A O   1 
HETATM 7277 O O   . HOH S 6 .   ? 10.90569  -32.56251 15.49610  1.000 43.05262  ? 509 HOH A O   1 
HETATM 7278 O O   . HOH S 6 .   ? -0.53700  -7.21657  13.10321  1.000 43.07183  ? 510 HOH A O   1 
HETATM 7279 O O   . HOH S 6 .   ? -10.27852 -20.19843 -4.98154  1.000 48.96028  ? 511 HOH A O   1 
HETATM 7280 O O   . HOH S 6 .   ? 8.94606   -12.35026 0.42239   1.000 55.04351  ? 512 HOH A O   1 
HETATM 7281 O O   . HOH S 6 .   ? 7.78360   -22.25913 26.24847  1.000 44.35918  ? 513 HOH A O   1 
HETATM 7282 O O   . HOH S 6 .   ? -3.56540  -13.95193 -21.48714 1.000 70.07946  ? 514 HOH A O   1 
HETATM 7283 O O   . HOH S 6 .   ? 18.31529  -30.09164 6.61745   1.000 70.47564  ? 515 HOH A O   1 
HETATM 7284 O O   . HOH S 6 .   ? -1.25064  -8.24396  15.21334  1.000 54.17587  ? 516 HOH A O   1 
HETATM 7285 O O   . HOH S 6 .   ? -5.45014  -34.11586 4.34396   1.000 55.48873  ? 517 HOH A O   1 
HETATM 7286 O O   . HOH S 6 .   ? -5.85020  -35.12530 2.36108   1.000 69.06340  ? 518 HOH A O   1 
HETATM 7287 O O   . HOH T 6 .   ? 29.68419  -47.08165 43.22323  1.000 47.94143  ? 501 HOH B O   1 
HETATM 7288 O O   . HOH T 6 .   ? 37.06109  -42.48480 18.24413  1.000 50.04476  ? 502 HOH B O   1 
HETATM 7289 O O   . HOH T 6 .   ? 23.06801  -51.64630 22.33945  1.000 66.33422  ? 503 HOH B O   1 
HETATM 7290 O O   . HOH T 6 .   ? 17.82958  -38.29150 20.45942  1.000 58.12068  ? 504 HOH B O   1 
HETATM 7291 O O   . HOH T 6 .   ? 39.46988  -66.36505 17.96352  1.000 71.40377  ? 505 HOH B O   1 
HETATM 7292 O O   . HOH T 6 .   ? 17.43957  -44.80489 17.57778  1.000 56.42306  ? 506 HOH B O   1 
HETATM 7293 O O   . HOH T 6 .   ? 29.74554  -28.05805 43.69413  1.000 54.91511  ? 507 HOH B O   1 
HETATM 7294 O O   . HOH T 6 .   ? 33.14433  -77.45281 36.70428  1.000 72.04562  ? 508 HOH B O   1 
HETATM 7295 O O   . HOH T 6 .   ? 44.759    -47.635   9.527     1.000 52.80176  ? 509 HOH B O   1 
HETATM 7296 O O   . HOH T 6 .   ? 35.71198  -42.26082 12.34889  1.000 58.20062  ? 510 HOH B O   1 
HETATM 7297 O O   . HOH T 6 .   ? 35.97926  -45.52141 14.60927  1.000 57.01250  ? 511 HOH B O   1 
HETATM 7298 O O   . HOH T 6 .   ? 31.53712  -37.97502 44.54553  1.000 56.48546  ? 512 HOH B O   1 
HETATM 7299 O O   . HOH T 6 .   ? 40.85109  -56.38339 34.39204  1.000 63.78997  ? 513 HOH B O   1 
HETATM 7300 O O   . HOH T 6 .   ? 43.72825  -46.33462 10.90177  1.000 48.31983  ? 514 HOH B O   1 
HETATM 7301 O O   . HOH T 6 .   ? 32.77505  -75.02909 38.27457  1.000 71.35698  ? 515 HOH B O   1 
HETATM 7302 O O   . HOH U 6 .   ? -12.41553 -20.73863 47.07334  1.000 67.40464  ? 501 HOH C O   1 
HETATM 7303 O O   . HOH U 6 .   ? -19.83863 -24.87397 43.31899  1.000 60.46495  ? 502 HOH C O   1 
HETATM 7304 O O   . HOH U 6 .   ? -11.28454 -28.67067 36.18213  1.000 51.66002  ? 503 HOH C O   1 
HETATM 7305 O O   . HOH U 6 .   ? 4.31629   -29.24844 24.23595  1.000 58.13922  ? 504 HOH C O   1 
HETATM 7306 O O   . HOH U 6 .   ? -29.88071 -30.90776 21.06549  1.000 54.37213  ? 505 HOH C O   1 
HETATM 7307 O O   . HOH U 6 .   ? -8.25139  -16.58923 35.42234  1.000 51.32216  ? 506 HOH C O   1 
HETATM 7308 O O   . HOH U 6 .   ? 8.50853   -46.23648 27.16361  1.000 52.88310  ? 507 HOH C O   1 
HETATM 7309 O O   . HOH U 6 .   ? 12.85252  -38.49147 14.61863  1.000 68.38470  ? 508 HOH C O   1 
HETATM 7310 O O   . HOH U 6 .   ? -8.55516  -40.57437 22.35837  1.000 56.63166  ? 509 HOH C O   1 
HETATM 7311 O O   . HOH U 6 .   ? -19.00163 -50.91927 29.64975  1.000 65.48262  ? 510 HOH C O   1 
HETATM 7312 O O   . HOH U 6 .   ? -12.60716 -8.55824  17.48181  1.000 56.63166  ? 511 HOH C O   1 
HETATM 7313 O O   . HOH U 6 .   ? -34.27185 -31.49277 19.69652  1.000 51.25899  ? 512 HOH C O   1 
# 
