data_9KQI
# 
_entry.id   9KQI 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9KQI         pdb_00009kqi 10.2210/pdb9kqi/pdb 
WWPDB D_1300054107 ?            ?                   
EMDB  EMD-62505    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-04-02 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9KQI 
_pdbx_database_status.recvd_initial_deposition_date   2024-11-26 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of PSS1 with calcium' 
_pdbx_database_related.db_id          EMD-62505 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              gejp@shanghaitech.edu.cn 
_pdbx_contact_author.name_first         Jingpeng 
_pdbx_contact_author.name_last          Ge 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-6164-1221 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Ning, Y.' 1 0009-0004-7041-1857 
'Yu, J.'   2 0000-0001-9227-038X 
'Ge, J.'   3 0000-0001-6164-1221 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Cell Discov' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2056-5968 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            11 
_citation.language                  ? 
_citation.page_first                20 
_citation.page_last                 20 
_citation.title                     'Structural basis for catalytic mechanism of human phosphatidylserine synthase 1.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41421-025-00775-3 
_citation.pdbx_database_id_PubMed   40044636 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Ning, Y.' 1 ?                   
primary 'Xu, R.'   2 ?                   
primary 'Yu, J.'   3 0000-0001-9227-038X 
primary 'Ge, J.'   4 0000-0001-6164-1221 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Phosphatidylserine synthase 1'                  55590.383 2  2.7.8.29 ? ? ? 
2 non-polymer syn 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE           455.437   4  ?        ? ? ? 
3 non-polymer syn Phosphatidylinositol                             887.128   2  ?        ? ? ? 
4 non-polymer syn 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine 760.076   10 ?        ? ? ? 
5 non-polymer syn DODECANE                                         170.335   2  ?        ? ? ? 
6 non-polymer syn TETRADECANE                                      198.388   2  ?        ? ? ? 
7 non-polymer syn 'CALCIUM ION'                                    40.078    2  ?        ? ? ? 
8 non-polymer syn SERINE                                           105.093   2  ?        ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'PSS-1,PtdSer synthase 1,Serine-exchange enzyme I' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MASCVGSRTLSKDDVNYKMHFRMINEQQVEDITIDFFYRPHTITLLSFTIVSLMYFAFTRDDSVPEDNIWRGILSVIFFF
LIISVLAFPNGPFTRPHPALWRMVFGLSVLYFLFLVFLLFLNFEQVKSLMYWLDPNLRYATREADVMEYAVNCHVITWER
IISHFDIFAFGHFWGWAMKALLIRSYGLCWTISITWELTELFFMHLLPNFAECWWDQVILDILLCNGGGIWLGMVVCRFL
EMRTYHWASFKDIHTTTGKIKRAVLQFTPASWTYVRWFDPKSSFQRVAGVYLFMIIWQLTELNTFFLKHIFVFQASHPLS
WGRILFIGGITAPTVRQYYAYLTDTQCKRVGTQCWVFGVIGFLEAIVCIKFGQDLFSKTQILYVVLWLLCVAFTTFLCLY
GMIWYAEHYGHREKTYSECEDGTYSPEISWHHRKGTKGSEDSPPKHAGNNESHSSRRRNRHSKSKVTNGVGKK
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MASCVGSRTLSKDDVNYKMHFRMINEQQVEDITIDFFYRPHTITLLSFTIVSLMYFAFTRDDSVPEDNIWRGILSVIFFF
LIISVLAFPNGPFTRPHPALWRMVFGLSVLYFLFLVFLLFLNFEQVKSLMYWLDPNLRYATREADVMEYAVNCHVITWER
IISHFDIFAFGHFWGWAMKALLIRSYGLCWTISITWELTELFFMHLLPNFAECWWDQVILDILLCNGGGIWLGMVVCRFL
EMRTYHWASFKDIHTTTGKIKRAVLQFTPASWTYVRWFDPKSSFQRVAGVYLFMIIWQLTELNTFFLKHIFVFQASHPLS
WGRILFIGGITAPTVRQYYAYLTDTQCKRVGTQCWVFGVIGFLEAIVCIKFGQDLFSKTQILYVVLWLLCVAFTTFLCLY
GMIWYAEHYGHREKTYSECEDGTYSPEISWHHRKGTKGSEDSPPKHAGNNESHSSRRRNRHSKSKVTNGVGKK
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE           PSF 
3 Phosphatidylinositol                             T7X 
4 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine LBN 
5 DODECANE                                         D12 
6 TETRADECANE                                      C14 
7 'CALCIUM ION'                                    CA  
8 SERINE                                           SER 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ALA n 
1 3   SER n 
1 4   CYS n 
1 5   VAL n 
1 6   GLY n 
1 7   SER n 
1 8   ARG n 
1 9   THR n 
1 10  LEU n 
1 11  SER n 
1 12  LYS n 
1 13  ASP n 
1 14  ASP n 
1 15  VAL n 
1 16  ASN n 
1 17  TYR n 
1 18  LYS n 
1 19  MET n 
1 20  HIS n 
1 21  PHE n 
1 22  ARG n 
1 23  MET n 
1 24  ILE n 
1 25  ASN n 
1 26  GLU n 
1 27  GLN n 
1 28  GLN n 
1 29  VAL n 
1 30  GLU n 
1 31  ASP n 
1 32  ILE n 
1 33  THR n 
1 34  ILE n 
1 35  ASP n 
1 36  PHE n 
1 37  PHE n 
1 38  TYR n 
1 39  ARG n 
1 40  PRO n 
1 41  HIS n 
1 42  THR n 
1 43  ILE n 
1 44  THR n 
1 45  LEU n 
1 46  LEU n 
1 47  SER n 
1 48  PHE n 
1 49  THR n 
1 50  ILE n 
1 51  VAL n 
1 52  SER n 
1 53  LEU n 
1 54  MET n 
1 55  TYR n 
1 56  PHE n 
1 57  ALA n 
1 58  PHE n 
1 59  THR n 
1 60  ARG n 
1 61  ASP n 
1 62  ASP n 
1 63  SER n 
1 64  VAL n 
1 65  PRO n 
1 66  GLU n 
1 67  ASP n 
1 68  ASN n 
1 69  ILE n 
1 70  TRP n 
1 71  ARG n 
1 72  GLY n 
1 73  ILE n 
1 74  LEU n 
1 75  SER n 
1 76  VAL n 
1 77  ILE n 
1 78  PHE n 
1 79  PHE n 
1 80  PHE n 
1 81  LEU n 
1 82  ILE n 
1 83  ILE n 
1 84  SER n 
1 85  VAL n 
1 86  LEU n 
1 87  ALA n 
1 88  PHE n 
1 89  PRO n 
1 90  ASN n 
1 91  GLY n 
1 92  PRO n 
1 93  PHE n 
1 94  THR n 
1 95  ARG n 
1 96  PRO n 
1 97  HIS n 
1 98  PRO n 
1 99  ALA n 
1 100 LEU n 
1 101 TRP n 
1 102 ARG n 
1 103 MET n 
1 104 VAL n 
1 105 PHE n 
1 106 GLY n 
1 107 LEU n 
1 108 SER n 
1 109 VAL n 
1 110 LEU n 
1 111 TYR n 
1 112 PHE n 
1 113 LEU n 
1 114 PHE n 
1 115 LEU n 
1 116 VAL n 
1 117 PHE n 
1 118 LEU n 
1 119 LEU n 
1 120 PHE n 
1 121 LEU n 
1 122 ASN n 
1 123 PHE n 
1 124 GLU n 
1 125 GLN n 
1 126 VAL n 
1 127 LYS n 
1 128 SER n 
1 129 LEU n 
1 130 MET n 
1 131 TYR n 
1 132 TRP n 
1 133 LEU n 
1 134 ASP n 
1 135 PRO n 
1 136 ASN n 
1 137 LEU n 
1 138 ARG n 
1 139 TYR n 
1 140 ALA n 
1 141 THR n 
1 142 ARG n 
1 143 GLU n 
1 144 ALA n 
1 145 ASP n 
1 146 VAL n 
1 147 MET n 
1 148 GLU n 
1 149 TYR n 
1 150 ALA n 
1 151 VAL n 
1 152 ASN n 
1 153 CYS n 
1 154 HIS n 
1 155 VAL n 
1 156 ILE n 
1 157 THR n 
1 158 TRP n 
1 159 GLU n 
1 160 ARG n 
1 161 ILE n 
1 162 ILE n 
1 163 SER n 
1 164 HIS n 
1 165 PHE n 
1 166 ASP n 
1 167 ILE n 
1 168 PHE n 
1 169 ALA n 
1 170 PHE n 
1 171 GLY n 
1 172 HIS n 
1 173 PHE n 
1 174 TRP n 
1 175 GLY n 
1 176 TRP n 
1 177 ALA n 
1 178 MET n 
1 179 LYS n 
1 180 ALA n 
1 181 LEU n 
1 182 LEU n 
1 183 ILE n 
1 184 ARG n 
1 185 SER n 
1 186 TYR n 
1 187 GLY n 
1 188 LEU n 
1 189 CYS n 
1 190 TRP n 
1 191 THR n 
1 192 ILE n 
1 193 SER n 
1 194 ILE n 
1 195 THR n 
1 196 TRP n 
1 197 GLU n 
1 198 LEU n 
1 199 THR n 
1 200 GLU n 
1 201 LEU n 
1 202 PHE n 
1 203 PHE n 
1 204 MET n 
1 205 HIS n 
1 206 LEU n 
1 207 LEU n 
1 208 PRO n 
1 209 ASN n 
1 210 PHE n 
1 211 ALA n 
1 212 GLU n 
1 213 CYS n 
1 214 TRP n 
1 215 TRP n 
1 216 ASP n 
1 217 GLN n 
1 218 VAL n 
1 219 ILE n 
1 220 LEU n 
1 221 ASP n 
1 222 ILE n 
1 223 LEU n 
1 224 LEU n 
1 225 CYS n 
1 226 ASN n 
1 227 GLY n 
1 228 GLY n 
1 229 GLY n 
1 230 ILE n 
1 231 TRP n 
1 232 LEU n 
1 233 GLY n 
1 234 MET n 
1 235 VAL n 
1 236 VAL n 
1 237 CYS n 
1 238 ARG n 
1 239 PHE n 
1 240 LEU n 
1 241 GLU n 
1 242 MET n 
1 243 ARG n 
1 244 THR n 
1 245 TYR n 
1 246 HIS n 
1 247 TRP n 
1 248 ALA n 
1 249 SER n 
1 250 PHE n 
1 251 LYS n 
1 252 ASP n 
1 253 ILE n 
1 254 HIS n 
1 255 THR n 
1 256 THR n 
1 257 THR n 
1 258 GLY n 
1 259 LYS n 
1 260 ILE n 
1 261 LYS n 
1 262 ARG n 
1 263 ALA n 
1 264 VAL n 
1 265 LEU n 
1 266 GLN n 
1 267 PHE n 
1 268 THR n 
1 269 PRO n 
1 270 ALA n 
1 271 SER n 
1 272 TRP n 
1 273 THR n 
1 274 TYR n 
1 275 VAL n 
1 276 ARG n 
1 277 TRP n 
1 278 PHE n 
1 279 ASP n 
1 280 PRO n 
1 281 LYS n 
1 282 SER n 
1 283 SER n 
1 284 PHE n 
1 285 GLN n 
1 286 ARG n 
1 287 VAL n 
1 288 ALA n 
1 289 GLY n 
1 290 VAL n 
1 291 TYR n 
1 292 LEU n 
1 293 PHE n 
1 294 MET n 
1 295 ILE n 
1 296 ILE n 
1 297 TRP n 
1 298 GLN n 
1 299 LEU n 
1 300 THR n 
1 301 GLU n 
1 302 LEU n 
1 303 ASN n 
1 304 THR n 
1 305 PHE n 
1 306 PHE n 
1 307 LEU n 
1 308 LYS n 
1 309 HIS n 
1 310 ILE n 
1 311 PHE n 
1 312 VAL n 
1 313 PHE n 
1 314 GLN n 
1 315 ALA n 
1 316 SER n 
1 317 HIS n 
1 318 PRO n 
1 319 LEU n 
1 320 SER n 
1 321 TRP n 
1 322 GLY n 
1 323 ARG n 
1 324 ILE n 
1 325 LEU n 
1 326 PHE n 
1 327 ILE n 
1 328 GLY n 
1 329 GLY n 
1 330 ILE n 
1 331 THR n 
1 332 ALA n 
1 333 PRO n 
1 334 THR n 
1 335 VAL n 
1 336 ARG n 
1 337 GLN n 
1 338 TYR n 
1 339 TYR n 
1 340 ALA n 
1 341 TYR n 
1 342 LEU n 
1 343 THR n 
1 344 ASP n 
1 345 THR n 
1 346 GLN n 
1 347 CYS n 
1 348 LYS n 
1 349 ARG n 
1 350 VAL n 
1 351 GLY n 
1 352 THR n 
1 353 GLN n 
1 354 CYS n 
1 355 TRP n 
1 356 VAL n 
1 357 PHE n 
1 358 GLY n 
1 359 VAL n 
1 360 ILE n 
1 361 GLY n 
1 362 PHE n 
1 363 LEU n 
1 364 GLU n 
1 365 ALA n 
1 366 ILE n 
1 367 VAL n 
1 368 CYS n 
1 369 ILE n 
1 370 LYS n 
1 371 PHE n 
1 372 GLY n 
1 373 GLN n 
1 374 ASP n 
1 375 LEU n 
1 376 PHE n 
1 377 SER n 
1 378 LYS n 
1 379 THR n 
1 380 GLN n 
1 381 ILE n 
1 382 LEU n 
1 383 TYR n 
1 384 VAL n 
1 385 VAL n 
1 386 LEU n 
1 387 TRP n 
1 388 LEU n 
1 389 LEU n 
1 390 CYS n 
1 391 VAL n 
1 392 ALA n 
1 393 PHE n 
1 394 THR n 
1 395 THR n 
1 396 PHE n 
1 397 LEU n 
1 398 CYS n 
1 399 LEU n 
1 400 TYR n 
1 401 GLY n 
1 402 MET n 
1 403 ILE n 
1 404 TRP n 
1 405 TYR n 
1 406 ALA n 
1 407 GLU n 
1 408 HIS n 
1 409 TYR n 
1 410 GLY n 
1 411 HIS n 
1 412 ARG n 
1 413 GLU n 
1 414 LYS n 
1 415 THR n 
1 416 TYR n 
1 417 SER n 
1 418 GLU n 
1 419 CYS n 
1 420 GLU n 
1 421 ASP n 
1 422 GLY n 
1 423 THR n 
1 424 TYR n 
1 425 SER n 
1 426 PRO n 
1 427 GLU n 
1 428 ILE n 
1 429 SER n 
1 430 TRP n 
1 431 HIS n 
1 432 HIS n 
1 433 ARG n 
1 434 LYS n 
1 435 GLY n 
1 436 THR n 
1 437 LYS n 
1 438 GLY n 
1 439 SER n 
1 440 GLU n 
1 441 ASP n 
1 442 SER n 
1 443 PRO n 
1 444 PRO n 
1 445 LYS n 
1 446 HIS n 
1 447 ALA n 
1 448 GLY n 
1 449 ASN n 
1 450 ASN n 
1 451 GLU n 
1 452 SER n 
1 453 HIS n 
1 454 SER n 
1 455 SER n 
1 456 ARG n 
1 457 ARG n 
1 458 ARG n 
1 459 ASN n 
1 460 ARG n 
1 461 HIS n 
1 462 SER n 
1 463 LYS n 
1 464 SER n 
1 465 LYS n 
1 466 VAL n 
1 467 THR n 
1 468 ASN n 
1 469 GLY n 
1 470 VAL n 
1 471 GLY n 
1 472 LYS n 
1 473 LYS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   473 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'PTDSS1, KIAA0024, PSSA' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     9606 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                          ? 'C3 H7 N O2'      89.093  
ARG 'L-peptide linking' y ARGININE                                         ? 'C6 H15 N4 O2 1'  175.209 
ASN 'L-peptide linking' y ASPARAGINE                                       ? 'C4 H8 N2 O3'     132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                                  ? 'C4 H7 N O4'      133.103 
C14 non-polymer         . TETRADECANE                                      ? 'C14 H30'         198.388 
CA  non-polymer         . 'CALCIUM ION'                                    ? 'Ca 2'            40.078  
CYS 'L-peptide linking' y CYSTEINE                                         ? 'C3 H7 N O2 S'    121.158 
D12 non-polymer         . DODECANE                                         ? 'C12 H26'         170.335 
GLN 'L-peptide linking' y GLUTAMINE                                        ? 'C5 H10 N2 O3'    146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                                  ? 'C5 H9 N O4'      147.129 
GLY 'peptide linking'   y GLYCINE                                          ? 'C2 H5 N O2'      75.067  
HIS 'L-peptide linking' y HISTIDINE                                        ? 'C6 H10 N3 O2 1'  156.162 
ILE 'L-peptide linking' y ISOLEUCINE                                       ? 'C6 H13 N O2'     131.173 
LBN non-polymer         . 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine 
'(2R)-2-[(9Z)-9-Octadecenoyloxy]-3-(palmitoyloxy)propyl 2-(trimethylammonio)ethyl phosphate' 'C42 H82 N O8 P'  760.076 
LEU 'L-peptide linking' y LEUCINE                                          ? 'C6 H13 N O2'     131.173 
LYS 'L-peptide linking' y LYSINE                                           ? 'C6 H15 N2 O2 1'  147.195 
MET 'L-peptide linking' y METHIONINE                                       ? 'C5 H11 N O2 S'   149.211 
PHE 'L-peptide linking' y PHENYLALANINE                                    ? 'C9 H11 N O2'     165.189 
PRO 'L-peptide linking' y PROLINE                                          ? 'C5 H9 N O2'      115.130 
PSF non-polymer         . 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE           PHOSPHATIDYLSERINE 'C18 H34 N O10 P' 455.437 
SER 'L-peptide linking' y SERINE                                           ? 'C3 H7 N O3'      105.093 
T7X non-polymer         . Phosphatidylinositol                             ? 'C47 H83 O13 P'   887.128 
THR 'L-peptide linking' y THREONINE                                        ? 'C4 H9 N O3'      119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                                       ? 'C11 H12 N2 O2'   204.225 
TYR 'L-peptide linking' y TYROSINE                                         ? 'C9 H11 N O3'     181.189 
VAL 'L-peptide linking' y VALINE                                           ? 'C5 H11 N O2'     117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   ALA 2   2   ?   ?   ?   A . n 
A 1 3   SER 3   3   ?   ?   ?   A . n 
A 1 4   CYS 4   4   ?   ?   ?   A . n 
A 1 5   VAL 5   5   ?   ?   ?   A . n 
A 1 6   GLY 6   6   ?   ?   ?   A . n 
A 1 7   SER 7   7   ?   ?   ?   A . n 
A 1 8   ARG 8   8   ?   ?   ?   A . n 
A 1 9   THR 9   9   ?   ?   ?   A . n 
A 1 10  LEU 10  10  ?   ?   ?   A . n 
A 1 11  SER 11  11  ?   ?   ?   A . n 
A 1 12  LYS 12  12  ?   ?   ?   A . n 
A 1 13  ASP 13  13  ?   ?   ?   A . n 
A 1 14  ASP 14  14  14  ASP ASP A . n 
A 1 15  VAL 15  15  15  VAL VAL A . n 
A 1 16  ASN 16  16  16  ASN ASN A . n 
A 1 17  TYR 17  17  17  TYR TYR A . n 
A 1 18  LYS 18  18  18  LYS LYS A . n 
A 1 19  MET 19  19  19  MET MET A . n 
A 1 20  HIS 20  20  20  HIS HIS A . n 
A 1 21  PHE 21  21  21  PHE PHE A . n 
A 1 22  ARG 22  22  22  ARG ARG A . n 
A 1 23  MET 23  23  23  MET MET A . n 
A 1 24  ILE 24  24  24  ILE ILE A . n 
A 1 25  ASN 25  25  25  ASN ASN A . n 
A 1 26  GLU 26  26  26  GLU GLU A . n 
A 1 27  GLN 27  27  27  GLN GLN A . n 
A 1 28  GLN 28  28  28  GLN GLN A . n 
A 1 29  VAL 29  29  29  VAL VAL A . n 
A 1 30  GLU 30  30  30  GLU GLU A . n 
A 1 31  ASP 31  31  31  ASP ASP A . n 
A 1 32  ILE 32  32  32  ILE ILE A . n 
A 1 33  THR 33  33  33  THR THR A . n 
A 1 34  ILE 34  34  34  ILE ILE A . n 
A 1 35  ASP 35  35  35  ASP ASP A . n 
A 1 36  PHE 36  36  36  PHE PHE A . n 
A 1 37  PHE 37  37  37  PHE PHE A . n 
A 1 38  TYR 38  38  38  TYR TYR A . n 
A 1 39  ARG 39  39  39  ARG ARG A . n 
A 1 40  PRO 40  40  40  PRO PRO A . n 
A 1 41  HIS 41  41  41  HIS HIS A . n 
A 1 42  THR 42  42  42  THR THR A . n 
A 1 43  ILE 43  43  43  ILE ILE A . n 
A 1 44  THR 44  44  44  THR THR A . n 
A 1 45  LEU 45  45  45  LEU LEU A . n 
A 1 46  LEU 46  46  46  LEU LEU A . n 
A 1 47  SER 47  47  47  SER SER A . n 
A 1 48  PHE 48  48  48  PHE PHE A . n 
A 1 49  THR 49  49  49  THR THR A . n 
A 1 50  ILE 50  50  50  ILE ILE A . n 
A 1 51  VAL 51  51  51  VAL VAL A . n 
A 1 52  SER 52  52  52  SER SER A . n 
A 1 53  LEU 53  53  53  LEU LEU A . n 
A 1 54  MET 54  54  54  MET MET A . n 
A 1 55  TYR 55  55  55  TYR TYR A . n 
A 1 56  PHE 56  56  56  PHE PHE A . n 
A 1 57  ALA 57  57  57  ALA ALA A . n 
A 1 58  PHE 58  58  58  PHE PHE A . n 
A 1 59  THR 59  59  59  THR THR A . n 
A 1 60  ARG 60  60  60  ARG ARG A . n 
A 1 61  ASP 61  61  61  ASP ASP A . n 
A 1 62  ASP 62  62  62  ASP ASP A . n 
A 1 63  SER 63  63  63  SER SER A . n 
A 1 64  VAL 64  64  64  VAL VAL A . n 
A 1 65  PRO 65  65  65  PRO PRO A . n 
A 1 66  GLU 66  66  66  GLU GLU A . n 
A 1 67  ASP 67  67  67  ASP ASP A . n 
A 1 68  ASN 68  68  68  ASN ASN A . n 
A 1 69  ILE 69  69  69  ILE ILE A . n 
A 1 70  TRP 70  70  70  TRP TRP A . n 
A 1 71  ARG 71  71  71  ARG ARG A . n 
A 1 72  GLY 72  72  72  GLY GLY A . n 
A 1 73  ILE 73  73  73  ILE ILE A . n 
A 1 74  LEU 74  74  74  LEU LEU A . n 
A 1 75  SER 75  75  75  SER SER A . n 
A 1 76  VAL 76  76  76  VAL VAL A . n 
A 1 77  ILE 77  77  77  ILE ILE A . n 
A 1 78  PHE 78  78  78  PHE PHE A . n 
A 1 79  PHE 79  79  79  PHE PHE A . n 
A 1 80  PHE 80  80  80  PHE PHE A . n 
A 1 81  LEU 81  81  81  LEU LEU A . n 
A 1 82  ILE 82  82  82  ILE ILE A . n 
A 1 83  ILE 83  83  83  ILE ILE A . n 
A 1 84  SER 84  84  84  SER SER A . n 
A 1 85  VAL 85  85  85  VAL VAL A . n 
A 1 86  LEU 86  86  86  LEU LEU A . n 
A 1 87  ALA 87  87  87  ALA ALA A . n 
A 1 88  PHE 88  88  88  PHE PHE A . n 
A 1 89  PRO 89  89  89  PRO PRO A . n 
A 1 90  ASN 90  90  90  ASN ASN A . n 
A 1 91  GLY 91  91  91  GLY GLY A . n 
A 1 92  PRO 92  92  92  PRO PRO A . n 
A 1 93  PHE 93  93  93  PHE PHE A . n 
A 1 94  THR 94  94  94  THR THR A . n 
A 1 95  ARG 95  95  95  ARG ARG A . n 
A 1 96  PRO 96  96  96  PRO PRO A . n 
A 1 97  HIS 97  97  97  HIS HIS A . n 
A 1 98  PRO 98  98  98  PRO PRO A . n 
A 1 99  ALA 99  99  99  ALA ALA A . n 
A 1 100 LEU 100 100 100 LEU LEU A . n 
A 1 101 TRP 101 101 101 TRP TRP A . n 
A 1 102 ARG 102 102 102 ARG ARG A . n 
A 1 103 MET 103 103 103 MET MET A . n 
A 1 104 VAL 104 104 104 VAL VAL A . n 
A 1 105 PHE 105 105 105 PHE PHE A . n 
A 1 106 GLY 106 106 106 GLY GLY A . n 
A 1 107 LEU 107 107 107 LEU LEU A . n 
A 1 108 SER 108 108 108 SER SER A . n 
A 1 109 VAL 109 109 109 VAL VAL A . n 
A 1 110 LEU 110 110 110 LEU LEU A . n 
A 1 111 TYR 111 111 111 TYR TYR A . n 
A 1 112 PHE 112 112 112 PHE PHE A . n 
A 1 113 LEU 113 113 113 LEU LEU A . n 
A 1 114 PHE 114 114 114 PHE PHE A . n 
A 1 115 LEU 115 115 115 LEU LEU A . n 
A 1 116 VAL 116 116 116 VAL VAL A . n 
A 1 117 PHE 117 117 117 PHE PHE A . n 
A 1 118 LEU 118 118 118 LEU LEU A . n 
A 1 119 LEU 119 119 119 LEU LEU A . n 
A 1 120 PHE 120 120 120 PHE PHE A . n 
A 1 121 LEU 121 121 121 LEU LEU A . n 
A 1 122 ASN 122 122 122 ASN ASN A . n 
A 1 123 PHE 123 123 123 PHE PHE A . n 
A 1 124 GLU 124 124 124 GLU GLU A . n 
A 1 125 GLN 125 125 125 GLN GLN A . n 
A 1 126 VAL 126 126 126 VAL VAL A . n 
A 1 127 LYS 127 127 127 LYS LYS A . n 
A 1 128 SER 128 128 128 SER SER A . n 
A 1 129 LEU 129 129 129 LEU LEU A . n 
A 1 130 MET 130 130 130 MET MET A . n 
A 1 131 TYR 131 131 131 TYR TYR A . n 
A 1 132 TRP 132 132 132 TRP TRP A . n 
A 1 133 LEU 133 133 133 LEU LEU A . n 
A 1 134 ASP 134 134 134 ASP ASP A . n 
A 1 135 PRO 135 135 135 PRO PRO A . n 
A 1 136 ASN 136 136 136 ASN ASN A . n 
A 1 137 LEU 137 137 137 LEU LEU A . n 
A 1 138 ARG 138 138 138 ARG ARG A . n 
A 1 139 TYR 139 139 139 TYR TYR A . n 
A 1 140 ALA 140 140 140 ALA ALA A . n 
A 1 141 THR 141 141 ?   ?   ?   A . n 
A 1 142 ARG 142 142 ?   ?   ?   A . n 
A 1 143 GLU 143 143 ?   ?   ?   A . n 
A 1 144 ALA 144 144 ?   ?   ?   A . n 
A 1 145 ASP 145 145 ?   ?   ?   A . n 
A 1 146 VAL 146 146 ?   ?   ?   A . n 
A 1 147 MET 147 147 ?   ?   ?   A . n 
A 1 148 GLU 148 148 ?   ?   ?   A . n 
A 1 149 TYR 149 149 ?   ?   ?   A . n 
A 1 150 ALA 150 150 ?   ?   ?   A . n 
A 1 151 VAL 151 151 ?   ?   ?   A . n 
A 1 152 ASN 152 152 ?   ?   ?   A . n 
A 1 153 CYS 153 153 ?   ?   ?   A . n 
A 1 154 HIS 154 154 ?   ?   ?   A . n 
A 1 155 VAL 155 155 ?   ?   ?   A . n 
A 1 156 ILE 156 156 ?   ?   ?   A . n 
A 1 157 THR 157 157 ?   ?   ?   A . n 
A 1 158 TRP 158 158 ?   ?   ?   A . n 
A 1 159 GLU 159 159 159 GLU GLU A . n 
A 1 160 ARG 160 160 160 ARG ARG A . n 
A 1 161 ILE 161 161 161 ILE ILE A . n 
A 1 162 ILE 162 162 162 ILE ILE A . n 
A 1 163 SER 163 163 163 SER SER A . n 
A 1 164 HIS 164 164 164 HIS HIS A . n 
A 1 165 PHE 165 165 165 PHE PHE A . n 
A 1 166 ASP 166 166 166 ASP ASP A . n 
A 1 167 ILE 167 167 167 ILE ILE A . n 
A 1 168 PHE 168 168 168 PHE PHE A . n 
A 1 169 ALA 169 169 169 ALA ALA A . n 
A 1 170 PHE 170 170 170 PHE PHE A . n 
A 1 171 GLY 171 171 171 GLY GLY A . n 
A 1 172 HIS 172 172 172 HIS HIS A . n 
A 1 173 PHE 173 173 173 PHE PHE A . n 
A 1 174 TRP 174 174 174 TRP TRP A . n 
A 1 175 GLY 175 175 175 GLY GLY A . n 
A 1 176 TRP 176 176 176 TRP TRP A . n 
A 1 177 ALA 177 177 177 ALA ALA A . n 
A 1 178 MET 178 178 178 MET MET A . n 
A 1 179 LYS 179 179 179 LYS LYS A . n 
A 1 180 ALA 180 180 180 ALA ALA A . n 
A 1 181 LEU 181 181 181 LEU LEU A . n 
A 1 182 LEU 182 182 182 LEU LEU A . n 
A 1 183 ILE 183 183 183 ILE ILE A . n 
A 1 184 ARG 184 184 184 ARG ARG A . n 
A 1 185 SER 185 185 185 SER SER A . n 
A 1 186 TYR 186 186 186 TYR TYR A . n 
A 1 187 GLY 187 187 187 GLY GLY A . n 
A 1 188 LEU 188 188 188 LEU LEU A . n 
A 1 189 CYS 189 189 189 CYS CYS A . n 
A 1 190 TRP 190 190 190 TRP TRP A . n 
A 1 191 THR 191 191 191 THR THR A . n 
A 1 192 ILE 192 192 192 ILE ILE A . n 
A 1 193 SER 193 193 193 SER SER A . n 
A 1 194 ILE 194 194 194 ILE ILE A . n 
A 1 195 THR 195 195 195 THR THR A . n 
A 1 196 TRP 196 196 196 TRP TRP A . n 
A 1 197 GLU 197 197 197 GLU GLU A . n 
A 1 198 LEU 198 198 198 LEU LEU A . n 
A 1 199 THR 199 199 199 THR THR A . n 
A 1 200 GLU 200 200 200 GLU GLU A . n 
A 1 201 LEU 201 201 201 LEU LEU A . n 
A 1 202 PHE 202 202 202 PHE PHE A . n 
A 1 203 PHE 203 203 203 PHE PHE A . n 
A 1 204 MET 204 204 204 MET MET A . n 
A 1 205 HIS 205 205 205 HIS HIS A . n 
A 1 206 LEU 206 206 206 LEU LEU A . n 
A 1 207 LEU 207 207 207 LEU LEU A . n 
A 1 208 PRO 208 208 208 PRO PRO A . n 
A 1 209 ASN 209 209 209 ASN ASN A . n 
A 1 210 PHE 210 210 210 PHE PHE A . n 
A 1 211 ALA 211 211 211 ALA ALA A . n 
A 1 212 GLU 212 212 212 GLU GLU A . n 
A 1 213 CYS 213 213 213 CYS CYS A . n 
A 1 214 TRP 214 214 214 TRP TRP A . n 
A 1 215 TRP 215 215 215 TRP TRP A . n 
A 1 216 ASP 216 216 216 ASP ASP A . n 
A 1 217 GLN 217 217 217 GLN GLN A . n 
A 1 218 VAL 218 218 218 VAL VAL A . n 
A 1 219 ILE 219 219 219 ILE ILE A . n 
A 1 220 LEU 220 220 220 LEU LEU A . n 
A 1 221 ASP 221 221 221 ASP ASP A . n 
A 1 222 ILE 222 222 222 ILE ILE A . n 
A 1 223 LEU 223 223 223 LEU LEU A . n 
A 1 224 LEU 224 224 224 LEU LEU A . n 
A 1 225 CYS 225 225 225 CYS CYS A . n 
A 1 226 ASN 226 226 226 ASN ASN A . n 
A 1 227 GLY 227 227 227 GLY GLY A . n 
A 1 228 GLY 228 228 228 GLY GLY A . n 
A 1 229 GLY 229 229 229 GLY GLY A . n 
A 1 230 ILE 230 230 230 ILE ILE A . n 
A 1 231 TRP 231 231 231 TRP TRP A . n 
A 1 232 LEU 232 232 232 LEU LEU A . n 
A 1 233 GLY 233 233 233 GLY GLY A . n 
A 1 234 MET 234 234 234 MET MET A . n 
A 1 235 VAL 235 235 235 VAL VAL A . n 
A 1 236 VAL 236 236 236 VAL VAL A . n 
A 1 237 CYS 237 237 237 CYS CYS A . n 
A 1 238 ARG 238 238 238 ARG ARG A . n 
A 1 239 PHE 239 239 239 PHE PHE A . n 
A 1 240 LEU 240 240 240 LEU LEU A . n 
A 1 241 GLU 241 241 241 GLU GLU A . n 
A 1 242 MET 242 242 242 MET MET A . n 
A 1 243 ARG 243 243 243 ARG ARG A . n 
A 1 244 THR 244 244 244 THR THR A . n 
A 1 245 TYR 245 245 245 TYR TYR A . n 
A 1 246 HIS 246 246 246 HIS HIS A . n 
A 1 247 TRP 247 247 247 TRP TRP A . n 
A 1 248 ALA 248 248 248 ALA ALA A . n 
A 1 249 SER 249 249 249 SER SER A . n 
A 1 250 PHE 250 250 250 PHE PHE A . n 
A 1 251 LYS 251 251 251 LYS LYS A . n 
A 1 252 ASP 252 252 252 ASP ASP A . n 
A 1 253 ILE 253 253 253 ILE ILE A . n 
A 1 254 HIS 254 254 254 HIS HIS A . n 
A 1 255 THR 255 255 255 THR THR A . n 
A 1 256 THR 256 256 256 THR THR A . n 
A 1 257 THR 257 257 257 THR THR A . n 
A 1 258 GLY 258 258 258 GLY GLY A . n 
A 1 259 LYS 259 259 259 LYS LYS A . n 
A 1 260 ILE 260 260 260 ILE ILE A . n 
A 1 261 LYS 261 261 261 LYS LYS A . n 
A 1 262 ARG 262 262 262 ARG ARG A . n 
A 1 263 ALA 263 263 263 ALA ALA A . n 
A 1 264 VAL 264 264 264 VAL VAL A . n 
A 1 265 LEU 265 265 265 LEU LEU A . n 
A 1 266 GLN 266 266 266 GLN GLN A . n 
A 1 267 PHE 267 267 267 PHE PHE A . n 
A 1 268 THR 268 268 268 THR THR A . n 
A 1 269 PRO 269 269 269 PRO PRO A . n 
A 1 270 ALA 270 270 270 ALA ALA A . n 
A 1 271 SER 271 271 271 SER SER A . n 
A 1 272 TRP 272 272 272 TRP TRP A . n 
A 1 273 THR 273 273 273 THR THR A . n 
A 1 274 TYR 274 274 274 TYR TYR A . n 
A 1 275 VAL 275 275 275 VAL VAL A . n 
A 1 276 ARG 276 276 276 ARG ARG A . n 
A 1 277 TRP 277 277 277 TRP TRP A . n 
A 1 278 PHE 278 278 278 PHE PHE A . n 
A 1 279 ASP 279 279 279 ASP ASP A . n 
A 1 280 PRO 280 280 280 PRO PRO A . n 
A 1 281 LYS 281 281 281 LYS LYS A . n 
A 1 282 SER 282 282 282 SER SER A . n 
A 1 283 SER 283 283 283 SER SER A . n 
A 1 284 PHE 284 284 284 PHE PHE A . n 
A 1 285 GLN 285 285 285 GLN GLN A . n 
A 1 286 ARG 286 286 286 ARG ARG A . n 
A 1 287 VAL 287 287 287 VAL VAL A . n 
A 1 288 ALA 288 288 288 ALA ALA A . n 
A 1 289 GLY 289 289 289 GLY GLY A . n 
A 1 290 VAL 290 290 290 VAL VAL A . n 
A 1 291 TYR 291 291 291 TYR TYR A . n 
A 1 292 LEU 292 292 292 LEU LEU A . n 
A 1 293 PHE 293 293 293 PHE PHE A . n 
A 1 294 MET 294 294 294 MET MET A . n 
A 1 295 ILE 295 295 295 ILE ILE A . n 
A 1 296 ILE 296 296 296 ILE ILE A . n 
A 1 297 TRP 297 297 297 TRP TRP A . n 
A 1 298 GLN 298 298 298 GLN GLN A . n 
A 1 299 LEU 299 299 299 LEU LEU A . n 
A 1 300 THR 300 300 300 THR THR A . n 
A 1 301 GLU 301 301 301 GLU GLU A . n 
A 1 302 LEU 302 302 302 LEU LEU A . n 
A 1 303 ASN 303 303 303 ASN ASN A . n 
A 1 304 THR 304 304 304 THR THR A . n 
A 1 305 PHE 305 305 305 PHE PHE A . n 
A 1 306 PHE 306 306 306 PHE PHE A . n 
A 1 307 LEU 307 307 307 LEU LEU A . n 
A 1 308 LYS 308 308 308 LYS LYS A . n 
A 1 309 HIS 309 309 309 HIS HIS A . n 
A 1 310 ILE 310 310 310 ILE ILE A . n 
A 1 311 PHE 311 311 311 PHE PHE A . n 
A 1 312 VAL 312 312 312 VAL VAL A . n 
A 1 313 PHE 313 313 313 PHE PHE A . n 
A 1 314 GLN 314 314 314 GLN GLN A . n 
A 1 315 ALA 315 315 315 ALA ALA A . n 
A 1 316 SER 316 316 316 SER SER A . n 
A 1 317 HIS 317 317 317 HIS HIS A . n 
A 1 318 PRO 318 318 318 PRO PRO A . n 
A 1 319 LEU 319 319 319 LEU LEU A . n 
A 1 320 SER 320 320 320 SER SER A . n 
A 1 321 TRP 321 321 321 TRP TRP A . n 
A 1 322 GLY 322 322 322 GLY GLY A . n 
A 1 323 ARG 323 323 323 ARG ARG A . n 
A 1 324 ILE 324 324 324 ILE ILE A . n 
A 1 325 LEU 325 325 325 LEU LEU A . n 
A 1 326 PHE 326 326 326 PHE PHE A . n 
A 1 327 ILE 327 327 327 ILE ILE A . n 
A 1 328 GLY 328 328 328 GLY GLY A . n 
A 1 329 GLY 329 329 329 GLY GLY A . n 
A 1 330 ILE 330 330 330 ILE ILE A . n 
A 1 331 THR 331 331 331 THR THR A . n 
A 1 332 ALA 332 332 332 ALA ALA A . n 
A 1 333 PRO 333 333 333 PRO PRO A . n 
A 1 334 THR 334 334 334 THR THR A . n 
A 1 335 VAL 335 335 335 VAL VAL A . n 
A 1 336 ARG 336 336 336 ARG ARG A . n 
A 1 337 GLN 337 337 337 GLN GLN A . n 
A 1 338 TYR 338 338 338 TYR TYR A . n 
A 1 339 TYR 339 339 339 TYR TYR A . n 
A 1 340 ALA 340 340 340 ALA ALA A . n 
A 1 341 TYR 341 341 341 TYR TYR A . n 
A 1 342 LEU 342 342 342 LEU LEU A . n 
A 1 343 THR 343 343 343 THR THR A . n 
A 1 344 ASP 344 344 344 ASP ASP A . n 
A 1 345 THR 345 345 345 THR THR A . n 
A 1 346 GLN 346 346 346 GLN GLN A . n 
A 1 347 CYS 347 347 347 CYS CYS A . n 
A 1 348 LYS 348 348 348 LYS LYS A . n 
A 1 349 ARG 349 349 349 ARG ARG A . n 
A 1 350 VAL 350 350 350 VAL VAL A . n 
A 1 351 GLY 351 351 351 GLY GLY A . n 
A 1 352 THR 352 352 352 THR THR A . n 
A 1 353 GLN 353 353 353 GLN GLN A . n 
A 1 354 CYS 354 354 354 CYS CYS A . n 
A 1 355 TRP 355 355 355 TRP TRP A . n 
A 1 356 VAL 356 356 356 VAL VAL A . n 
A 1 357 PHE 357 357 357 PHE PHE A . n 
A 1 358 GLY 358 358 358 GLY GLY A . n 
A 1 359 VAL 359 359 359 VAL VAL A . n 
A 1 360 ILE 360 360 360 ILE ILE A . n 
A 1 361 GLY 361 361 361 GLY GLY A . n 
A 1 362 PHE 362 362 362 PHE PHE A . n 
A 1 363 LEU 363 363 363 LEU LEU A . n 
A 1 364 GLU 364 364 364 GLU GLU A . n 
A 1 365 ALA 365 365 365 ALA ALA A . n 
A 1 366 ILE 366 366 366 ILE ILE A . n 
A 1 367 VAL 367 367 367 VAL VAL A . n 
A 1 368 CYS 368 368 368 CYS CYS A . n 
A 1 369 ILE 369 369 369 ILE ILE A . n 
A 1 370 LYS 370 370 370 LYS LYS A . n 
A 1 371 PHE 371 371 371 PHE PHE A . n 
A 1 372 GLY 372 372 372 GLY GLY A . n 
A 1 373 GLN 373 373 373 GLN GLN A . n 
A 1 374 ASP 374 374 374 ASP ASP A . n 
A 1 375 LEU 375 375 375 LEU LEU A . n 
A 1 376 PHE 376 376 376 PHE PHE A . n 
A 1 377 SER 377 377 377 SER SER A . n 
A 1 378 LYS 378 378 378 LYS LYS A . n 
A 1 379 THR 379 379 379 THR THR A . n 
A 1 380 GLN 380 380 380 GLN GLN A . n 
A 1 381 ILE 381 381 381 ILE ILE A . n 
A 1 382 LEU 382 382 382 LEU LEU A . n 
A 1 383 TYR 383 383 383 TYR TYR A . n 
A 1 384 VAL 384 384 384 VAL VAL A . n 
A 1 385 VAL 385 385 385 VAL VAL A . n 
A 1 386 LEU 386 386 386 LEU LEU A . n 
A 1 387 TRP 387 387 387 TRP TRP A . n 
A 1 388 LEU 388 388 388 LEU LEU A . n 
A 1 389 LEU 389 389 389 LEU LEU A . n 
A 1 390 CYS 390 390 390 CYS CYS A . n 
A 1 391 VAL 391 391 391 VAL VAL A . n 
A 1 392 ALA 392 392 392 ALA ALA A . n 
A 1 393 PHE 393 393 393 PHE PHE A . n 
A 1 394 THR 394 394 394 THR THR A . n 
A 1 395 THR 395 395 395 THR THR A . n 
A 1 396 PHE 396 396 396 PHE PHE A . n 
A 1 397 LEU 397 397 397 LEU LEU A . n 
A 1 398 CYS 398 398 398 CYS CYS A . n 
A 1 399 LEU 399 399 399 LEU LEU A . n 
A 1 400 TYR 400 400 400 TYR TYR A . n 
A 1 401 GLY 401 401 401 GLY GLY A . n 
A 1 402 MET 402 402 402 MET MET A . n 
A 1 403 ILE 403 403 403 ILE ILE A . n 
A 1 404 TRP 404 404 404 TRP TRP A . n 
A 1 405 TYR 405 405 405 TYR TYR A . n 
A 1 406 ALA 406 406 406 ALA ALA A . n 
A 1 407 GLU 407 407 407 GLU GLU A . n 
A 1 408 HIS 408 408 408 HIS HIS A . n 
A 1 409 TYR 409 409 ?   ?   ?   A . n 
A 1 410 GLY 410 410 ?   ?   ?   A . n 
A 1 411 HIS 411 411 ?   ?   ?   A . n 
A 1 412 ARG 412 412 ?   ?   ?   A . n 
A 1 413 GLU 413 413 ?   ?   ?   A . n 
A 1 414 LYS 414 414 ?   ?   ?   A . n 
A 1 415 THR 415 415 ?   ?   ?   A . n 
A 1 416 TYR 416 416 ?   ?   ?   A . n 
A 1 417 SER 417 417 ?   ?   ?   A . n 
A 1 418 GLU 418 418 ?   ?   ?   A . n 
A 1 419 CYS 419 419 ?   ?   ?   A . n 
A 1 420 GLU 420 420 ?   ?   ?   A . n 
A 1 421 ASP 421 421 ?   ?   ?   A . n 
A 1 422 GLY 422 422 ?   ?   ?   A . n 
A 1 423 THR 423 423 ?   ?   ?   A . n 
A 1 424 TYR 424 424 ?   ?   ?   A . n 
A 1 425 SER 425 425 ?   ?   ?   A . n 
A 1 426 PRO 426 426 ?   ?   ?   A . n 
A 1 427 GLU 427 427 ?   ?   ?   A . n 
A 1 428 ILE 428 428 ?   ?   ?   A . n 
A 1 429 SER 429 429 ?   ?   ?   A . n 
A 1 430 TRP 430 430 ?   ?   ?   A . n 
A 1 431 HIS 431 431 ?   ?   ?   A . n 
A 1 432 HIS 432 432 ?   ?   ?   A . n 
A 1 433 ARG 433 433 ?   ?   ?   A . n 
A 1 434 LYS 434 434 ?   ?   ?   A . n 
A 1 435 GLY 435 435 ?   ?   ?   A . n 
A 1 436 THR 436 436 ?   ?   ?   A . n 
A 1 437 LYS 437 437 ?   ?   ?   A . n 
A 1 438 GLY 438 438 ?   ?   ?   A . n 
A 1 439 SER 439 439 ?   ?   ?   A . n 
A 1 440 GLU 440 440 ?   ?   ?   A . n 
A 1 441 ASP 441 441 ?   ?   ?   A . n 
A 1 442 SER 442 442 ?   ?   ?   A . n 
A 1 443 PRO 443 443 ?   ?   ?   A . n 
A 1 444 PRO 444 444 ?   ?   ?   A . n 
A 1 445 LYS 445 445 ?   ?   ?   A . n 
A 1 446 HIS 446 446 ?   ?   ?   A . n 
A 1 447 ALA 447 447 ?   ?   ?   A . n 
A 1 448 GLY 448 448 ?   ?   ?   A . n 
A 1 449 ASN 449 449 ?   ?   ?   A . n 
A 1 450 ASN 450 450 ?   ?   ?   A . n 
A 1 451 GLU 451 451 ?   ?   ?   A . n 
A 1 452 SER 452 452 ?   ?   ?   A . n 
A 1 453 HIS 453 453 ?   ?   ?   A . n 
A 1 454 SER 454 454 ?   ?   ?   A . n 
A 1 455 SER 455 455 ?   ?   ?   A . n 
A 1 456 ARG 456 456 ?   ?   ?   A . n 
A 1 457 ARG 457 457 ?   ?   ?   A . n 
A 1 458 ARG 458 458 ?   ?   ?   A . n 
A 1 459 ASN 459 459 ?   ?   ?   A . n 
A 1 460 ARG 460 460 ?   ?   ?   A . n 
A 1 461 HIS 461 461 ?   ?   ?   A . n 
A 1 462 SER 462 462 ?   ?   ?   A . n 
A 1 463 LYS 463 463 ?   ?   ?   A . n 
A 1 464 SER 464 464 ?   ?   ?   A . n 
A 1 465 LYS 465 465 ?   ?   ?   A . n 
A 1 466 VAL 466 466 ?   ?   ?   A . n 
A 1 467 THR 467 467 ?   ?   ?   A . n 
A 1 468 ASN 468 468 ?   ?   ?   A . n 
A 1 469 GLY 469 469 ?   ?   ?   A . n 
A 1 470 VAL 470 470 ?   ?   ?   A . n 
A 1 471 GLY 471 471 ?   ?   ?   A . n 
A 1 472 LYS 472 472 ?   ?   ?   A . n 
A 1 473 LYS 473 473 ?   ?   ?   A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   ALA 2   2   ?   ?   ?   B . n 
B 1 3   SER 3   3   ?   ?   ?   B . n 
B 1 4   CYS 4   4   ?   ?   ?   B . n 
B 1 5   VAL 5   5   ?   ?   ?   B . n 
B 1 6   GLY 6   6   ?   ?   ?   B . n 
B 1 7   SER 7   7   ?   ?   ?   B . n 
B 1 8   ARG 8   8   ?   ?   ?   B . n 
B 1 9   THR 9   9   ?   ?   ?   B . n 
B 1 10  LEU 10  10  ?   ?   ?   B . n 
B 1 11  SER 11  11  ?   ?   ?   B . n 
B 1 12  LYS 12  12  ?   ?   ?   B . n 
B 1 13  ASP 13  13  ?   ?   ?   B . n 
B 1 14  ASP 14  14  14  ASP ASP B . n 
B 1 15  VAL 15  15  15  VAL VAL B . n 
B 1 16  ASN 16  16  16  ASN ASN B . n 
B 1 17  TYR 17  17  17  TYR TYR B . n 
B 1 18  LYS 18  18  18  LYS LYS B . n 
B 1 19  MET 19  19  19  MET MET B . n 
B 1 20  HIS 20  20  20  HIS HIS B . n 
B 1 21  PHE 21  21  21  PHE PHE B . n 
B 1 22  ARG 22  22  22  ARG ARG B . n 
B 1 23  MET 23  23  23  MET MET B . n 
B 1 24  ILE 24  24  24  ILE ILE B . n 
B 1 25  ASN 25  25  25  ASN ASN B . n 
B 1 26  GLU 26  26  26  GLU GLU B . n 
B 1 27  GLN 27  27  27  GLN GLN B . n 
B 1 28  GLN 28  28  28  GLN GLN B . n 
B 1 29  VAL 29  29  29  VAL VAL B . n 
B 1 30  GLU 30  30  30  GLU GLU B . n 
B 1 31  ASP 31  31  31  ASP ASP B . n 
B 1 32  ILE 32  32  32  ILE ILE B . n 
B 1 33  THR 33  33  33  THR THR B . n 
B 1 34  ILE 34  34  34  ILE ILE B . n 
B 1 35  ASP 35  35  35  ASP ASP B . n 
B 1 36  PHE 36  36  36  PHE PHE B . n 
B 1 37  PHE 37  37  37  PHE PHE B . n 
B 1 38  TYR 38  38  38  TYR TYR B . n 
B 1 39  ARG 39  39  39  ARG ARG B . n 
B 1 40  PRO 40  40  40  PRO PRO B . n 
B 1 41  HIS 41  41  41  HIS HIS B . n 
B 1 42  THR 42  42  42  THR THR B . n 
B 1 43  ILE 43  43  43  ILE ILE B . n 
B 1 44  THR 44  44  44  THR THR B . n 
B 1 45  LEU 45  45  45  LEU LEU B . n 
B 1 46  LEU 46  46  46  LEU LEU B . n 
B 1 47  SER 47  47  47  SER SER B . n 
B 1 48  PHE 48  48  48  PHE PHE B . n 
B 1 49  THR 49  49  49  THR THR B . n 
B 1 50  ILE 50  50  50  ILE ILE B . n 
B 1 51  VAL 51  51  51  VAL VAL B . n 
B 1 52  SER 52  52  52  SER SER B . n 
B 1 53  LEU 53  53  53  LEU LEU B . n 
B 1 54  MET 54  54  54  MET MET B . n 
B 1 55  TYR 55  55  55  TYR TYR B . n 
B 1 56  PHE 56  56  56  PHE PHE B . n 
B 1 57  ALA 57  57  57  ALA ALA B . n 
B 1 58  PHE 58  58  58  PHE PHE B . n 
B 1 59  THR 59  59  59  THR THR B . n 
B 1 60  ARG 60  60  60  ARG ARG B . n 
B 1 61  ASP 61  61  61  ASP ASP B . n 
B 1 62  ASP 62  62  62  ASP ASP B . n 
B 1 63  SER 63  63  63  SER SER B . n 
B 1 64  VAL 64  64  64  VAL VAL B . n 
B 1 65  PRO 65  65  65  PRO PRO B . n 
B 1 66  GLU 66  66  66  GLU GLU B . n 
B 1 67  ASP 67  67  67  ASP ASP B . n 
B 1 68  ASN 68  68  68  ASN ASN B . n 
B 1 69  ILE 69  69  69  ILE ILE B . n 
B 1 70  TRP 70  70  70  TRP TRP B . n 
B 1 71  ARG 71  71  71  ARG ARG B . n 
B 1 72  GLY 72  72  72  GLY GLY B . n 
B 1 73  ILE 73  73  73  ILE ILE B . n 
B 1 74  LEU 74  74  74  LEU LEU B . n 
B 1 75  SER 75  75  75  SER SER B . n 
B 1 76  VAL 76  76  76  VAL VAL B . n 
B 1 77  ILE 77  77  77  ILE ILE B . n 
B 1 78  PHE 78  78  78  PHE PHE B . n 
B 1 79  PHE 79  79  79  PHE PHE B . n 
B 1 80  PHE 80  80  80  PHE PHE B . n 
B 1 81  LEU 81  81  81  LEU LEU B . n 
B 1 82  ILE 82  82  82  ILE ILE B . n 
B 1 83  ILE 83  83  83  ILE ILE B . n 
B 1 84  SER 84  84  84  SER SER B . n 
B 1 85  VAL 85  85  85  VAL VAL B . n 
B 1 86  LEU 86  86  86  LEU LEU B . n 
B 1 87  ALA 87  87  87  ALA ALA B . n 
B 1 88  PHE 88  88  88  PHE PHE B . n 
B 1 89  PRO 89  89  89  PRO PRO B . n 
B 1 90  ASN 90  90  90  ASN ASN B . n 
B 1 91  GLY 91  91  91  GLY GLY B . n 
B 1 92  PRO 92  92  92  PRO PRO B . n 
B 1 93  PHE 93  93  93  PHE PHE B . n 
B 1 94  THR 94  94  94  THR THR B . n 
B 1 95  ARG 95  95  95  ARG ARG B . n 
B 1 96  PRO 96  96  96  PRO PRO B . n 
B 1 97  HIS 97  97  97  HIS HIS B . n 
B 1 98  PRO 98  98  98  PRO PRO B . n 
B 1 99  ALA 99  99  99  ALA ALA B . n 
B 1 100 LEU 100 100 100 LEU LEU B . n 
B 1 101 TRP 101 101 101 TRP TRP B . n 
B 1 102 ARG 102 102 102 ARG ARG B . n 
B 1 103 MET 103 103 103 MET MET B . n 
B 1 104 VAL 104 104 104 VAL VAL B . n 
B 1 105 PHE 105 105 105 PHE PHE B . n 
B 1 106 GLY 106 106 106 GLY GLY B . n 
B 1 107 LEU 107 107 107 LEU LEU B . n 
B 1 108 SER 108 108 108 SER SER B . n 
B 1 109 VAL 109 109 109 VAL VAL B . n 
B 1 110 LEU 110 110 110 LEU LEU B . n 
B 1 111 TYR 111 111 111 TYR TYR B . n 
B 1 112 PHE 112 112 112 PHE PHE B . n 
B 1 113 LEU 113 113 113 LEU LEU B . n 
B 1 114 PHE 114 114 114 PHE PHE B . n 
B 1 115 LEU 115 115 115 LEU LEU B . n 
B 1 116 VAL 116 116 116 VAL VAL B . n 
B 1 117 PHE 117 117 117 PHE PHE B . n 
B 1 118 LEU 118 118 118 LEU LEU B . n 
B 1 119 LEU 119 119 119 LEU LEU B . n 
B 1 120 PHE 120 120 120 PHE PHE B . n 
B 1 121 LEU 121 121 121 LEU LEU B . n 
B 1 122 ASN 122 122 122 ASN ASN B . n 
B 1 123 PHE 123 123 123 PHE PHE B . n 
B 1 124 GLU 124 124 124 GLU GLU B . n 
B 1 125 GLN 125 125 125 GLN GLN B . n 
B 1 126 VAL 126 126 126 VAL VAL B . n 
B 1 127 LYS 127 127 127 LYS LYS B . n 
B 1 128 SER 128 128 128 SER SER B . n 
B 1 129 LEU 129 129 129 LEU LEU B . n 
B 1 130 MET 130 130 130 MET MET B . n 
B 1 131 TYR 131 131 131 TYR TYR B . n 
B 1 132 TRP 132 132 132 TRP TRP B . n 
B 1 133 LEU 133 133 133 LEU LEU B . n 
B 1 134 ASP 134 134 134 ASP ASP B . n 
B 1 135 PRO 135 135 135 PRO PRO B . n 
B 1 136 ASN 136 136 136 ASN ASN B . n 
B 1 137 LEU 137 137 137 LEU LEU B . n 
B 1 138 ARG 138 138 138 ARG ARG B . n 
B 1 139 TYR 139 139 139 TYR TYR B . n 
B 1 140 ALA 140 140 140 ALA ALA B . n 
B 1 141 THR 141 141 ?   ?   ?   B . n 
B 1 142 ARG 142 142 ?   ?   ?   B . n 
B 1 143 GLU 143 143 ?   ?   ?   B . n 
B 1 144 ALA 144 144 ?   ?   ?   B . n 
B 1 145 ASP 145 145 ?   ?   ?   B . n 
B 1 146 VAL 146 146 ?   ?   ?   B . n 
B 1 147 MET 147 147 ?   ?   ?   B . n 
B 1 148 GLU 148 148 ?   ?   ?   B . n 
B 1 149 TYR 149 149 ?   ?   ?   B . n 
B 1 150 ALA 150 150 ?   ?   ?   B . n 
B 1 151 VAL 151 151 ?   ?   ?   B . n 
B 1 152 ASN 152 152 ?   ?   ?   B . n 
B 1 153 CYS 153 153 ?   ?   ?   B . n 
B 1 154 HIS 154 154 ?   ?   ?   B . n 
B 1 155 VAL 155 155 ?   ?   ?   B . n 
B 1 156 ILE 156 156 ?   ?   ?   B . n 
B 1 157 THR 157 157 ?   ?   ?   B . n 
B 1 158 TRP 158 158 ?   ?   ?   B . n 
B 1 159 GLU 159 159 159 GLU GLU B . n 
B 1 160 ARG 160 160 160 ARG ARG B . n 
B 1 161 ILE 161 161 161 ILE ILE B . n 
B 1 162 ILE 162 162 162 ILE ILE B . n 
B 1 163 SER 163 163 163 SER SER B . n 
B 1 164 HIS 164 164 164 HIS HIS B . n 
B 1 165 PHE 165 165 165 PHE PHE B . n 
B 1 166 ASP 166 166 166 ASP ASP B . n 
B 1 167 ILE 167 167 167 ILE ILE B . n 
B 1 168 PHE 168 168 168 PHE PHE B . n 
B 1 169 ALA 169 169 169 ALA ALA B . n 
B 1 170 PHE 170 170 170 PHE PHE B . n 
B 1 171 GLY 171 171 171 GLY GLY B . n 
B 1 172 HIS 172 172 172 HIS HIS B . n 
B 1 173 PHE 173 173 173 PHE PHE B . n 
B 1 174 TRP 174 174 174 TRP TRP B . n 
B 1 175 GLY 175 175 175 GLY GLY B . n 
B 1 176 TRP 176 176 176 TRP TRP B . n 
B 1 177 ALA 177 177 177 ALA ALA B . n 
B 1 178 MET 178 178 178 MET MET B . n 
B 1 179 LYS 179 179 179 LYS LYS B . n 
B 1 180 ALA 180 180 180 ALA ALA B . n 
B 1 181 LEU 181 181 181 LEU LEU B . n 
B 1 182 LEU 182 182 182 LEU LEU B . n 
B 1 183 ILE 183 183 183 ILE ILE B . n 
B 1 184 ARG 184 184 184 ARG ARG B . n 
B 1 185 SER 185 185 185 SER SER B . n 
B 1 186 TYR 186 186 186 TYR TYR B . n 
B 1 187 GLY 187 187 187 GLY GLY B . n 
B 1 188 LEU 188 188 188 LEU LEU B . n 
B 1 189 CYS 189 189 189 CYS CYS B . n 
B 1 190 TRP 190 190 190 TRP TRP B . n 
B 1 191 THR 191 191 191 THR THR B . n 
B 1 192 ILE 192 192 192 ILE ILE B . n 
B 1 193 SER 193 193 193 SER SER B . n 
B 1 194 ILE 194 194 194 ILE ILE B . n 
B 1 195 THR 195 195 195 THR THR B . n 
B 1 196 TRP 196 196 196 TRP TRP B . n 
B 1 197 GLU 197 197 197 GLU GLU B . n 
B 1 198 LEU 198 198 198 LEU LEU B . n 
B 1 199 THR 199 199 199 THR THR B . n 
B 1 200 GLU 200 200 200 GLU GLU B . n 
B 1 201 LEU 201 201 201 LEU LEU B . n 
B 1 202 PHE 202 202 202 PHE PHE B . n 
B 1 203 PHE 203 203 203 PHE PHE B . n 
B 1 204 MET 204 204 204 MET MET B . n 
B 1 205 HIS 205 205 205 HIS HIS B . n 
B 1 206 LEU 206 206 206 LEU LEU B . n 
B 1 207 LEU 207 207 207 LEU LEU B . n 
B 1 208 PRO 208 208 208 PRO PRO B . n 
B 1 209 ASN 209 209 209 ASN ASN B . n 
B 1 210 PHE 210 210 210 PHE PHE B . n 
B 1 211 ALA 211 211 211 ALA ALA B . n 
B 1 212 GLU 212 212 212 GLU GLU B . n 
B 1 213 CYS 213 213 213 CYS CYS B . n 
B 1 214 TRP 214 214 214 TRP TRP B . n 
B 1 215 TRP 215 215 215 TRP TRP B . n 
B 1 216 ASP 216 216 216 ASP ASP B . n 
B 1 217 GLN 217 217 217 GLN GLN B . n 
B 1 218 VAL 218 218 218 VAL VAL B . n 
B 1 219 ILE 219 219 219 ILE ILE B . n 
B 1 220 LEU 220 220 220 LEU LEU B . n 
B 1 221 ASP 221 221 221 ASP ASP B . n 
B 1 222 ILE 222 222 222 ILE ILE B . n 
B 1 223 LEU 223 223 223 LEU LEU B . n 
B 1 224 LEU 224 224 224 LEU LEU B . n 
B 1 225 CYS 225 225 225 CYS CYS B . n 
B 1 226 ASN 226 226 226 ASN ASN B . n 
B 1 227 GLY 227 227 227 GLY GLY B . n 
B 1 228 GLY 228 228 228 GLY GLY B . n 
B 1 229 GLY 229 229 229 GLY GLY B . n 
B 1 230 ILE 230 230 230 ILE ILE B . n 
B 1 231 TRP 231 231 231 TRP TRP B . n 
B 1 232 LEU 232 232 232 LEU LEU B . n 
B 1 233 GLY 233 233 233 GLY GLY B . n 
B 1 234 MET 234 234 234 MET MET B . n 
B 1 235 VAL 235 235 235 VAL VAL B . n 
B 1 236 VAL 236 236 236 VAL VAL B . n 
B 1 237 CYS 237 237 237 CYS CYS B . n 
B 1 238 ARG 238 238 238 ARG ARG B . n 
B 1 239 PHE 239 239 239 PHE PHE B . n 
B 1 240 LEU 240 240 240 LEU LEU B . n 
B 1 241 GLU 241 241 241 GLU GLU B . n 
B 1 242 MET 242 242 242 MET MET B . n 
B 1 243 ARG 243 243 243 ARG ARG B . n 
B 1 244 THR 244 244 244 THR THR B . n 
B 1 245 TYR 245 245 245 TYR TYR B . n 
B 1 246 HIS 246 246 246 HIS HIS B . n 
B 1 247 TRP 247 247 247 TRP TRP B . n 
B 1 248 ALA 248 248 248 ALA ALA B . n 
B 1 249 SER 249 249 249 SER SER B . n 
B 1 250 PHE 250 250 250 PHE PHE B . n 
B 1 251 LYS 251 251 251 LYS LYS B . n 
B 1 252 ASP 252 252 252 ASP ASP B . n 
B 1 253 ILE 253 253 253 ILE ILE B . n 
B 1 254 HIS 254 254 254 HIS HIS B . n 
B 1 255 THR 255 255 255 THR THR B . n 
B 1 256 THR 256 256 256 THR THR B . n 
B 1 257 THR 257 257 257 THR THR B . n 
B 1 258 GLY 258 258 258 GLY GLY B . n 
B 1 259 LYS 259 259 259 LYS LYS B . n 
B 1 260 ILE 260 260 260 ILE ILE B . n 
B 1 261 LYS 261 261 261 LYS LYS B . n 
B 1 262 ARG 262 262 262 ARG ARG B . n 
B 1 263 ALA 263 263 263 ALA ALA B . n 
B 1 264 VAL 264 264 264 VAL VAL B . n 
B 1 265 LEU 265 265 265 LEU LEU B . n 
B 1 266 GLN 266 266 266 GLN GLN B . n 
B 1 267 PHE 267 267 267 PHE PHE B . n 
B 1 268 THR 268 268 268 THR THR B . n 
B 1 269 PRO 269 269 269 PRO PRO B . n 
B 1 270 ALA 270 270 270 ALA ALA B . n 
B 1 271 SER 271 271 271 SER SER B . n 
B 1 272 TRP 272 272 272 TRP TRP B . n 
B 1 273 THR 273 273 273 THR THR B . n 
B 1 274 TYR 274 274 274 TYR TYR B . n 
B 1 275 VAL 275 275 275 VAL VAL B . n 
B 1 276 ARG 276 276 276 ARG ARG B . n 
B 1 277 TRP 277 277 277 TRP TRP B . n 
B 1 278 PHE 278 278 278 PHE PHE B . n 
B 1 279 ASP 279 279 279 ASP ASP B . n 
B 1 280 PRO 280 280 280 PRO PRO B . n 
B 1 281 LYS 281 281 281 LYS LYS B . n 
B 1 282 SER 282 282 282 SER SER B . n 
B 1 283 SER 283 283 283 SER SER B . n 
B 1 284 PHE 284 284 284 PHE PHE B . n 
B 1 285 GLN 285 285 285 GLN GLN B . n 
B 1 286 ARG 286 286 286 ARG ARG B . n 
B 1 287 VAL 287 287 287 VAL VAL B . n 
B 1 288 ALA 288 288 288 ALA ALA B . n 
B 1 289 GLY 289 289 289 GLY GLY B . n 
B 1 290 VAL 290 290 290 VAL VAL B . n 
B 1 291 TYR 291 291 291 TYR TYR B . n 
B 1 292 LEU 292 292 292 LEU LEU B . n 
B 1 293 PHE 293 293 293 PHE PHE B . n 
B 1 294 MET 294 294 294 MET MET B . n 
B 1 295 ILE 295 295 295 ILE ILE B . n 
B 1 296 ILE 296 296 296 ILE ILE B . n 
B 1 297 TRP 297 297 297 TRP TRP B . n 
B 1 298 GLN 298 298 298 GLN GLN B . n 
B 1 299 LEU 299 299 299 LEU LEU B . n 
B 1 300 THR 300 300 300 THR THR B . n 
B 1 301 GLU 301 301 301 GLU GLU B . n 
B 1 302 LEU 302 302 302 LEU LEU B . n 
B 1 303 ASN 303 303 303 ASN ASN B . n 
B 1 304 THR 304 304 304 THR THR B . n 
B 1 305 PHE 305 305 305 PHE PHE B . n 
B 1 306 PHE 306 306 306 PHE PHE B . n 
B 1 307 LEU 307 307 307 LEU LEU B . n 
B 1 308 LYS 308 308 308 LYS LYS B . n 
B 1 309 HIS 309 309 309 HIS HIS B . n 
B 1 310 ILE 310 310 310 ILE ILE B . n 
B 1 311 PHE 311 311 311 PHE PHE B . n 
B 1 312 VAL 312 312 312 VAL VAL B . n 
B 1 313 PHE 313 313 313 PHE PHE B . n 
B 1 314 GLN 314 314 314 GLN GLN B . n 
B 1 315 ALA 315 315 315 ALA ALA B . n 
B 1 316 SER 316 316 316 SER SER B . n 
B 1 317 HIS 317 317 317 HIS HIS B . n 
B 1 318 PRO 318 318 318 PRO PRO B . n 
B 1 319 LEU 319 319 319 LEU LEU B . n 
B 1 320 SER 320 320 320 SER SER B . n 
B 1 321 TRP 321 321 321 TRP TRP B . n 
B 1 322 GLY 322 322 322 GLY GLY B . n 
B 1 323 ARG 323 323 323 ARG ARG B . n 
B 1 324 ILE 324 324 324 ILE ILE B . n 
B 1 325 LEU 325 325 325 LEU LEU B . n 
B 1 326 PHE 326 326 326 PHE PHE B . n 
B 1 327 ILE 327 327 327 ILE ILE B . n 
B 1 328 GLY 328 328 328 GLY GLY B . n 
B 1 329 GLY 329 329 329 GLY GLY B . n 
B 1 330 ILE 330 330 330 ILE ILE B . n 
B 1 331 THR 331 331 331 THR THR B . n 
B 1 332 ALA 332 332 332 ALA ALA B . n 
B 1 333 PRO 333 333 333 PRO PRO B . n 
B 1 334 THR 334 334 334 THR THR B . n 
B 1 335 VAL 335 335 335 VAL VAL B . n 
B 1 336 ARG 336 336 336 ARG ARG B . n 
B 1 337 GLN 337 337 337 GLN GLN B . n 
B 1 338 TYR 338 338 338 TYR TYR B . n 
B 1 339 TYR 339 339 339 TYR TYR B . n 
B 1 340 ALA 340 340 340 ALA ALA B . n 
B 1 341 TYR 341 341 341 TYR TYR B . n 
B 1 342 LEU 342 342 342 LEU LEU B . n 
B 1 343 THR 343 343 343 THR THR B . n 
B 1 344 ASP 344 344 344 ASP ASP B . n 
B 1 345 THR 345 345 345 THR THR B . n 
B 1 346 GLN 346 346 346 GLN GLN B . n 
B 1 347 CYS 347 347 347 CYS CYS B . n 
B 1 348 LYS 348 348 348 LYS LYS B . n 
B 1 349 ARG 349 349 349 ARG ARG B . n 
B 1 350 VAL 350 350 350 VAL VAL B . n 
B 1 351 GLY 351 351 351 GLY GLY B . n 
B 1 352 THR 352 352 352 THR THR B . n 
B 1 353 GLN 353 353 353 GLN GLN B . n 
B 1 354 CYS 354 354 354 CYS CYS B . n 
B 1 355 TRP 355 355 355 TRP TRP B . n 
B 1 356 VAL 356 356 356 VAL VAL B . n 
B 1 357 PHE 357 357 357 PHE PHE B . n 
B 1 358 GLY 358 358 358 GLY GLY B . n 
B 1 359 VAL 359 359 359 VAL VAL B . n 
B 1 360 ILE 360 360 360 ILE ILE B . n 
B 1 361 GLY 361 361 361 GLY GLY B . n 
B 1 362 PHE 362 362 362 PHE PHE B . n 
B 1 363 LEU 363 363 363 LEU LEU B . n 
B 1 364 GLU 364 364 364 GLU GLU B . n 
B 1 365 ALA 365 365 365 ALA ALA B . n 
B 1 366 ILE 366 366 366 ILE ILE B . n 
B 1 367 VAL 367 367 367 VAL VAL B . n 
B 1 368 CYS 368 368 368 CYS CYS B . n 
B 1 369 ILE 369 369 369 ILE ILE B . n 
B 1 370 LYS 370 370 370 LYS LYS B . n 
B 1 371 PHE 371 371 371 PHE PHE B . n 
B 1 372 GLY 372 372 372 GLY GLY B . n 
B 1 373 GLN 373 373 373 GLN GLN B . n 
B 1 374 ASP 374 374 374 ASP ASP B . n 
B 1 375 LEU 375 375 375 LEU LEU B . n 
B 1 376 PHE 376 376 376 PHE PHE B . n 
B 1 377 SER 377 377 377 SER SER B . n 
B 1 378 LYS 378 378 378 LYS LYS B . n 
B 1 379 THR 379 379 379 THR THR B . n 
B 1 380 GLN 380 380 380 GLN GLN B . n 
B 1 381 ILE 381 381 381 ILE ILE B . n 
B 1 382 LEU 382 382 382 LEU LEU B . n 
B 1 383 TYR 383 383 383 TYR TYR B . n 
B 1 384 VAL 384 384 384 VAL VAL B . n 
B 1 385 VAL 385 385 385 VAL VAL B . n 
B 1 386 LEU 386 386 386 LEU LEU B . n 
B 1 387 TRP 387 387 387 TRP TRP B . n 
B 1 388 LEU 388 388 388 LEU LEU B . n 
B 1 389 LEU 389 389 389 LEU LEU B . n 
B 1 390 CYS 390 390 390 CYS CYS B . n 
B 1 391 VAL 391 391 391 VAL VAL B . n 
B 1 392 ALA 392 392 392 ALA ALA B . n 
B 1 393 PHE 393 393 393 PHE PHE B . n 
B 1 394 THR 394 394 394 THR THR B . n 
B 1 395 THR 395 395 395 THR THR B . n 
B 1 396 PHE 396 396 396 PHE PHE B . n 
B 1 397 LEU 397 397 397 LEU LEU B . n 
B 1 398 CYS 398 398 398 CYS CYS B . n 
B 1 399 LEU 399 399 399 LEU LEU B . n 
B 1 400 TYR 400 400 400 TYR TYR B . n 
B 1 401 GLY 401 401 401 GLY GLY B . n 
B 1 402 MET 402 402 402 MET MET B . n 
B 1 403 ILE 403 403 403 ILE ILE B . n 
B 1 404 TRP 404 404 404 TRP TRP B . n 
B 1 405 TYR 405 405 405 TYR TYR B . n 
B 1 406 ALA 406 406 406 ALA ALA B . n 
B 1 407 GLU 407 407 407 GLU GLU B . n 
B 1 408 HIS 408 408 408 HIS HIS B . n 
B 1 409 TYR 409 409 ?   ?   ?   B . n 
B 1 410 GLY 410 410 ?   ?   ?   B . n 
B 1 411 HIS 411 411 ?   ?   ?   B . n 
B 1 412 ARG 412 412 ?   ?   ?   B . n 
B 1 413 GLU 413 413 ?   ?   ?   B . n 
B 1 414 LYS 414 414 ?   ?   ?   B . n 
B 1 415 THR 415 415 ?   ?   ?   B . n 
B 1 416 TYR 416 416 ?   ?   ?   B . n 
B 1 417 SER 417 417 ?   ?   ?   B . n 
B 1 418 GLU 418 418 ?   ?   ?   B . n 
B 1 419 CYS 419 419 ?   ?   ?   B . n 
B 1 420 GLU 420 420 ?   ?   ?   B . n 
B 1 421 ASP 421 421 ?   ?   ?   B . n 
B 1 422 GLY 422 422 ?   ?   ?   B . n 
B 1 423 THR 423 423 ?   ?   ?   B . n 
B 1 424 TYR 424 424 ?   ?   ?   B . n 
B 1 425 SER 425 425 ?   ?   ?   B . n 
B 1 426 PRO 426 426 ?   ?   ?   B . n 
B 1 427 GLU 427 427 ?   ?   ?   B . n 
B 1 428 ILE 428 428 ?   ?   ?   B . n 
B 1 429 SER 429 429 ?   ?   ?   B . n 
B 1 430 TRP 430 430 ?   ?   ?   B . n 
B 1 431 HIS 431 431 ?   ?   ?   B . n 
B 1 432 HIS 432 432 ?   ?   ?   B . n 
B 1 433 ARG 433 433 ?   ?   ?   B . n 
B 1 434 LYS 434 434 ?   ?   ?   B . n 
B 1 435 GLY 435 435 ?   ?   ?   B . n 
B 1 436 THR 436 436 ?   ?   ?   B . n 
B 1 437 LYS 437 437 ?   ?   ?   B . n 
B 1 438 GLY 438 438 ?   ?   ?   B . n 
B 1 439 SER 439 439 ?   ?   ?   B . n 
B 1 440 GLU 440 440 ?   ?   ?   B . n 
B 1 441 ASP 441 441 ?   ?   ?   B . n 
B 1 442 SER 442 442 ?   ?   ?   B . n 
B 1 443 PRO 443 443 ?   ?   ?   B . n 
B 1 444 PRO 444 444 ?   ?   ?   B . n 
B 1 445 LYS 445 445 ?   ?   ?   B . n 
B 1 446 HIS 446 446 ?   ?   ?   B . n 
B 1 447 ALA 447 447 ?   ?   ?   B . n 
B 1 448 GLY 448 448 ?   ?   ?   B . n 
B 1 449 ASN 449 449 ?   ?   ?   B . n 
B 1 450 ASN 450 450 ?   ?   ?   B . n 
B 1 451 GLU 451 451 ?   ?   ?   B . n 
B 1 452 SER 452 452 ?   ?   ?   B . n 
B 1 453 HIS 453 453 ?   ?   ?   B . n 
B 1 454 SER 454 454 ?   ?   ?   B . n 
B 1 455 SER 455 455 ?   ?   ?   B . n 
B 1 456 ARG 456 456 ?   ?   ?   B . n 
B 1 457 ARG 457 457 ?   ?   ?   B . n 
B 1 458 ARG 458 458 ?   ?   ?   B . n 
B 1 459 ASN 459 459 ?   ?   ?   B . n 
B 1 460 ARG 460 460 ?   ?   ?   B . n 
B 1 461 HIS 461 461 ?   ?   ?   B . n 
B 1 462 SER 462 462 ?   ?   ?   B . n 
B 1 463 LYS 463 463 ?   ?   ?   B . n 
B 1 464 SER 464 464 ?   ?   ?   B . n 
B 1 465 LYS 465 465 ?   ?   ?   B . n 
B 1 466 VAL 466 466 ?   ?   ?   B . n 
B 1 467 THR 467 467 ?   ?   ?   B . n 
B 1 468 ASN 468 468 ?   ?   ?   B . n 
B 1 469 GLY 469 469 ?   ?   ?   B . n 
B 1 470 VAL 470 470 ?   ?   ?   B . n 
B 1 471 GLY 471 471 ?   ?   ?   B . n 
B 1 472 LYS 472 472 ?   ?   ?   B . n 
B 1 473 LYS 473 473 ?   ?   ?   B . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 LBN ? ? LBN ? ? 'SUBJECT OF INVESTIGATION' ? 
2 PSF ? ? PSF ? ? 'SUBJECT OF INVESTIGATION' ? 
3 T7X ? ? T7X ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 PSF 1 501 502 PSF PSF A . 
D 2 PSF 1 502 503 PSF PSF A . 
E 3 T7X 1 503 504 T7X T7X A . 
F 4 LBN 1 504 505 LBN LBN A . 
G 4 LBN 1 505 507 LBN LBN A . 
H 5 D12 1 506 508 D12 D12 A . 
I 6 C14 1 507 509 C14 C14 A . 
J 4 LBN 1 508 510 LBN LBN A . 
K 7 CA  1 509 512 CA  CA  A . 
L 4 LBN 1 510 513 LBN LBN A . 
M 8 SER 1 511 514 SER SER A . 
N 4 LBN 1 512 511 LBN LBN A . 
O 4 LBN 1 501 511 LBN LBN B . 
P 2 PSF 1 502 502 PSF PSF B . 
Q 2 PSF 1 503 503 PSF PSF B . 
R 3 T7X 1 504 504 T7X T7X B . 
S 4 LBN 1 505 505 LBN LBN B . 
T 4 LBN 1 506 507 LBN LBN B . 
U 5 D12 1 507 508 D12 D12 B . 
V 6 C14 1 508 509 C14 C14 B . 
W 4 LBN 1 509 510 LBN LBN B . 
X 7 CA  1 510 512 CA  CA  B . 
Y 4 LBN 1 511 513 LBN LBN B . 
Z 8 SER 1 512 514 SER SER B . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 N 1 A T7X 503 ? C39 ? E T7X 1 C39 
2  1 N 1 A T7X 503 ? C40 ? E T7X 1 C40 
3  1 N 1 A T7X 503 ? C41 ? E T7X 1 C41 
4  1 N 1 A T7X 503 ? C29 ? E T7X 1 C29 
5  1 N 1 A T7X 503 ? C30 ? E T7X 1 C30 
6  1 N 1 A T7X 503 ? C42 ? E T7X 1 C42 
7  1 N 1 A T7X 503 ? C43 ? E T7X 1 C43 
8  1 N 1 A T7X 503 ? C44 ? E T7X 1 C44 
9  1 N 1 A T7X 503 ? C45 ? E T7X 1 C45 
10 1 N 1 A T7X 503 ? C46 ? E T7X 1 C46 
11 1 N 1 A T7X 503 ? C47 ? E T7X 1 C47 
12 1 N 1 A LBN 505 ? C4  ? G LBN 1 C4  
13 1 N 1 A LBN 505 ? C5  ? G LBN 1 C5  
14 1 N 1 A LBN 505 ? C7  ? G LBN 1 C7  
15 1 N 1 A LBN 505 ? C8  ? G LBN 1 C8  
16 1 N 1 A LBN 505 ? C10 ? G LBN 1 C10 
17 1 N 1 A LBN 505 ? C11 ? G LBN 1 C11 
18 1 N 1 A LBN 505 ? C13 ? G LBN 1 C13 
19 1 N 1 A LBN 505 ? C14 ? G LBN 1 C14 
20 1 N 1 A LBN 505 ? C16 ? G LBN 1 C16 
21 1 N 1 A LBN 505 ? C17 ? G LBN 1 C17 
22 1 N 1 A LBN 505 ? C19 ? G LBN 1 C19 
23 1 N 1 A LBN 505 ? C20 ? G LBN 1 C20 
24 1 N 1 A LBN 505 ? C21 ? G LBN 1 C21 
25 1 N 1 A LBN 505 ? C22 ? G LBN 1 C22 
26 1 N 1 A LBN 505 ? C23 ? G LBN 1 C23 
27 1 N 1 A LBN 505 ? C24 ? G LBN 1 C24 
28 1 N 1 A LBN 505 ? C31 ? G LBN 1 C31 
29 1 N 1 A LBN 505 ? C32 ? G LBN 1 C32 
30 1 N 1 A LBN 505 ? C33 ? G LBN 1 C33 
31 1 N 1 A LBN 505 ? C42 ? G LBN 1 C42 
32 1 N 1 A LBN 512 ? C5  ? N LBN 1 C5  
33 1 N 1 A LBN 512 ? C8  ? N LBN 1 C8  
34 1 N 1 A LBN 512 ? C11 ? N LBN 1 C11 
35 1 N 1 A LBN 512 ? C14 ? N LBN 1 C14 
36 1 N 1 A LBN 512 ? C17 ? N LBN 1 C17 
37 1 N 1 A LBN 512 ? C20 ? N LBN 1 C20 
38 1 N 1 A LBN 512 ? C22 ? N LBN 1 C22 
39 1 N 1 A LBN 512 ? C23 ? N LBN 1 C23 
40 1 N 1 A LBN 512 ? C24 ? N LBN 1 C24 
41 1 N 1 A LBN 512 ? C38 ? N LBN 1 C38 
42 1 N 1 A LBN 512 ? C39 ? N LBN 1 C39 
43 1 N 1 A LBN 512 ? C40 ? N LBN 1 C40 
44 1 N 1 A LBN 512 ? C41 ? N LBN 1 C41 
45 1 N 1 A LBN 512 ? C42 ? N LBN 1 C42 
46 1 N 1 B LBN 501 ? C5  ? O LBN 1 C5  
47 1 N 1 B LBN 501 ? C8  ? O LBN 1 C8  
48 1 N 1 B LBN 501 ? C11 ? O LBN 1 C11 
49 1 N 1 B LBN 501 ? C14 ? O LBN 1 C14 
50 1 N 1 B LBN 501 ? C17 ? O LBN 1 C17 
51 1 N 1 B LBN 501 ? C20 ? O LBN 1 C20 
52 1 N 1 B LBN 501 ? C22 ? O LBN 1 C22 
53 1 N 1 B LBN 501 ? C23 ? O LBN 1 C23 
54 1 N 1 B LBN 501 ? C24 ? O LBN 1 C24 
55 1 N 1 B LBN 501 ? C38 ? O LBN 1 C38 
56 1 N 1 B LBN 501 ? C39 ? O LBN 1 C39 
57 1 N 1 B LBN 501 ? C40 ? O LBN 1 C40 
58 1 N 1 B LBN 501 ? C41 ? O LBN 1 C41 
59 1 N 1 B LBN 501 ? C42 ? O LBN 1 C42 
60 1 N 1 B T7X 504 ? C39 ? R T7X 1 C39 
61 1 N 1 B T7X 504 ? C40 ? R T7X 1 C40 
62 1 N 1 B T7X 504 ? C41 ? R T7X 1 C41 
63 1 N 1 B T7X 504 ? C29 ? R T7X 1 C29 
64 1 N 1 B T7X 504 ? C30 ? R T7X 1 C30 
65 1 N 1 B T7X 504 ? C42 ? R T7X 1 C42 
66 1 N 1 B T7X 504 ? C43 ? R T7X 1 C43 
67 1 N 1 B T7X 504 ? C44 ? R T7X 1 C44 
68 1 N 1 B T7X 504 ? C45 ? R T7X 1 C45 
69 1 N 1 B T7X 504 ? C46 ? R T7X 1 C46 
70 1 N 1 B T7X 504 ? C47 ? R T7X 1 C47 
71 1 N 1 B LBN 506 ? C4  ? T LBN 1 C4  
72 1 N 1 B LBN 506 ? C5  ? T LBN 1 C5  
73 1 N 1 B LBN 506 ? C7  ? T LBN 1 C7  
74 1 N 1 B LBN 506 ? C8  ? T LBN 1 C8  
75 1 N 1 B LBN 506 ? C10 ? T LBN 1 C10 
76 1 N 1 B LBN 506 ? C11 ? T LBN 1 C11 
77 1 N 1 B LBN 506 ? C13 ? T LBN 1 C13 
78 1 N 1 B LBN 506 ? C14 ? T LBN 1 C14 
79 1 N 1 B LBN 506 ? C16 ? T LBN 1 C16 
80 1 N 1 B LBN 506 ? C17 ? T LBN 1 C17 
81 1 N 1 B LBN 506 ? C19 ? T LBN 1 C19 
82 1 N 1 B LBN 506 ? C20 ? T LBN 1 C20 
83 1 N 1 B LBN 506 ? C21 ? T LBN 1 C21 
84 1 N 1 B LBN 506 ? C22 ? T LBN 1 C22 
85 1 N 1 B LBN 506 ? C23 ? T LBN 1 C23 
86 1 N 1 B LBN 506 ? C24 ? T LBN 1 C24 
87 1 N 1 B LBN 506 ? C31 ? T LBN 1 C31 
88 1 N 1 B LBN 506 ? C32 ? T LBN 1 C32 
89 1 N 1 B LBN 506 ? C33 ? T LBN 1 C33 
90 1 N 1 B LBN 506 ? C42 ? T LBN 1 C42 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9KQI 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9KQI 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9KQI 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9KQI 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            3.02 
_refine.ls_d_res_low                             ? 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'REAL-SPACE (WEIGHTED MAP SUM AT ATOM CENTERS)' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.005  ? 7288 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.550  ? 9796 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 18.893 ? 1246 ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.042  ? 1004 ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.004  ? 1128 ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9KQI 
_struct.title                        'Cryo-EM structure of PSS1 with calcium' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9KQI 
_struct_keywords.text            
'phosphatidylserine synthase, ER membrane protein, integral membrane protein, transmembrane enzyme, PS, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 2 ? 
E N N 3 ? 
F N N 4 ? 
G N N 4 ? 
H N N 5 ? 
I N N 6 ? 
J N N 4 ? 
K N N 7 ? 
L N N 4 ? 
M N N 8 ? 
N N N 4 ? 
O N N 4 ? 
P N N 2 ? 
Q N N 2 ? 
R N N 3 ? 
S N N 4 ? 
T N N 4 ? 
U N N 5 ? 
V N N 6 ? 
W N N 4 ? 
X N N 7 ? 
Y N N 4 ? 
Z N N 8 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    PTSS1_HUMAN 
_struct_ref.pdbx_db_accession          P48651 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MASCVGSRTLSKDDVNYKMHFRMINEQQVEDITIDFFYRPHTITLLSFTIVSLMYFAFTRDDSVPEDNIWRGILSVIFFF
LIISVLAFPNGPFTRPHPALWRMVFGLSVLYFLFLVFLLFLNFEQVKSLMYWLDPNLRYATREADVMEYAVNCHVITWER
IISHFDIFAFGHFWGWAMKALLIRSYGLCWTISITWELTELFFMHLLPNFAECWWDQVILDILLCNGGGIWLGMVVCRFL
EMRTYHWASFKDIHTTTGKIKRAVLQFTPASWTYVRWFDPKSSFQRVAGVYLFMIIWQLTELNTFFLKHIFVFQASHPLS
WGRILFIGGITAPTVRQYYAYLTDTQCKRVGTQCWVFGVIGFLEAIVCIKFGQDLFSKTQILYVVLWLLCVAFTTFLCLY
GMIWYAEHYGHREKTYSECEDGTYSPEISWHHRKGTKGSEDSPPKHAGNNESHSSRRRNRHSKSKVTNGVGKK
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9KQI A 1 ? 473 ? P48651 1 ? 473 ? 1 473 
2 1 9KQI B 1 ? 473 ? P48651 1 ? 473 ? 1 473 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X,Y,Z 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ASP A 14  ? MET A 23  ? ASP A 14  MET A 23  1 ? 10 
HELX_P HELX_P2  AA2 ILE A 34  ? ARG A 39  ? ILE A 34  ARG A 39  5 ? 6  
HELX_P HELX_P3  AA3 HIS A 41  ? THR A 59  ? HIS A 41  THR A 59  1 ? 19 
HELX_P HELX_P4  AA4 VAL A 64  ? PHE A 88  ? VAL A 64  PHE A 88  1 ? 25 
HELX_P HELX_P5  AA5 PRO A 98  ? LEU A 119 ? PRO A 98  LEU A 119 1 ? 22 
HELX_P HELX_P6  AA6 ASN A 122 ? ASP A 134 ? ASN A 122 ASP A 134 1 ? 13 
HELX_P HELX_P7  AA7 PRO A 135 ? ALA A 140 ? PRO A 135 ALA A 140 1 ? 6  
HELX_P HELX_P8  AA8 ARG A 160 ? PHE A 165 ? ARG A 160 PHE A 165 1 ? 6  
HELX_P HELX_P9  AA9 ASP A 166 ? ARG A 184 ? ASP A 166 ARG A 184 1 ? 19 
HELX_P HELX_P10 AB1 SER A 185 ? MET A 204 ? SER A 185 MET A 204 1 ? 20 
HELX_P HELX_P11 AB2 CYS A 213 ? GLN A 217 ? CYS A 213 GLN A 217 5 ? 5  
HELX_P HELX_P12 AB3 LEU A 224 ? MET A 242 ? LEU A 224 MET A 242 1 ? 19 
HELX_P HELX_P13 AB4 THR A 255 ? GLN A 266 ? THR A 255 GLN A 266 1 ? 12 
HELX_P HELX_P14 AB5 SER A 283 ? PHE A 311 ? SER A 283 PHE A 311 1 ? 29 
HELX_P HELX_P15 AB6 HIS A 317 ? ASP A 344 ? HIS A 317 ASP A 344 1 ? 28 
HELX_P HELX_P16 AB7 GLY A 351 ? GLY A 372 ? GLY A 351 GLY A 372 1 ? 22 
HELX_P HELX_P17 AB8 ILE A 381 ? HIS A 408 ? ILE A 381 HIS A 408 1 ? 28 
HELX_P HELX_P18 AB9 VAL B 15  ? MET B 23  ? VAL B 15  MET B 23  1 ? 9  
HELX_P HELX_P19 AC1 ILE B 34  ? ARG B 39  ? ILE B 34  ARG B 39  5 ? 6  
HELX_P HELX_P20 AC2 HIS B 41  ? THR B 59  ? HIS B 41  THR B 59  1 ? 19 
HELX_P HELX_P21 AC3 VAL B 64  ? PHE B 88  ? VAL B 64  PHE B 88  1 ? 25 
HELX_P HELX_P22 AC4 PRO B 98  ? LEU B 119 ? PRO B 98  LEU B 119 1 ? 22 
HELX_P HELX_P23 AC5 ASN B 122 ? ASP B 134 ? ASN B 122 ASP B 134 1 ? 13 
HELX_P HELX_P24 AC6 PRO B 135 ? ALA B 140 ? PRO B 135 ALA B 140 1 ? 6  
HELX_P HELX_P25 AC7 ARG B 160 ? PHE B 165 ? ARG B 160 PHE B 165 1 ? 6  
HELX_P HELX_P26 AC8 ASP B 166 ? ARG B 184 ? ASP B 166 ARG B 184 1 ? 19 
HELX_P HELX_P27 AC9 SER B 185 ? MET B 204 ? SER B 185 MET B 204 1 ? 20 
HELX_P HELX_P28 AD1 CYS B 213 ? ILE B 219 ? CYS B 213 ILE B 219 1 ? 7  
HELX_P HELX_P29 AD2 LEU B 224 ? MET B 242 ? LEU B 224 MET B 242 1 ? 19 
HELX_P HELX_P30 AD3 THR B 255 ? GLN B 266 ? THR B 255 GLN B 266 1 ? 12 
HELX_P HELX_P31 AD4 SER B 283 ? PHE B 311 ? SER B 283 PHE B 311 1 ? 29 
HELX_P HELX_P32 AD5 HIS B 317 ? ASP B 344 ? HIS B 317 ASP B 344 1 ? 28 
HELX_P HELX_P33 AD6 GLY B 351 ? GLY B 372 ? GLY B 351 GLY B 372 1 ? 22 
HELX_P HELX_P34 AD7 ILE B 381 ? HIS B 408 ? ILE B 381 HIS B 408 1 ? 28 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1 metalc ? ? A GLU 197 OE1 ? ? ? 1_555 K CA  . CA ? ? A GLU 197 A CA  509 1_555 ? ? ? ? ? ? ? 3.035 ? ? 
metalc2 metalc ? ? A GLU 200 OE1 ? ? ? 1_555 K CA  . CA ? ? A GLU 200 A CA  509 1_555 ? ? ? ? ? ? ? 2.419 ? ? 
metalc3 metalc ? ? A GLN 217 OE1 ? ? ? 1_555 K CA  . CA ? ? A GLN 217 A CA  509 1_555 ? ? ? ? ? ? ? 2.780 ? ? 
metalc4 metalc ? ? K CA  .   CA  ? ? ? 1_555 M SER . O  ? ? A CA  509 A SER 511 1_555 ? ? ? ? ? ? ? 2.484 ? ? 
metalc5 metalc ? ? B GLU 197 OE1 ? ? ? 1_555 X CA  . CA ? ? B GLU 197 B CA  510 1_555 ? ? ? ? ? ? ? 2.793 ? ? 
metalc6 metalc ? ? B GLU 200 OE1 ? ? ? 1_555 X CA  . CA ? ? B GLU 200 B CA  510 1_555 ? ? ? ? ? ? ? 2.465 ? ? 
metalc7 metalc ? ? B GLN 217 OE1 ? ? ? 1_555 X CA  . CA ? ? B GLN 217 B CA  510 1_555 ? ? ? ? ? ? ? 2.809 ? ? 
metalc8 metalc ? ? X CA  .   CA  ? ? ? 1_555 Z SER . O  ? ? B CA  510 B SER 512 1_555 ? ? ? ? ? ? ? 2.445 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  OE1 ? A GLU 197 ? A GLU 197 ? 1_555 CA ? K CA . ? A CA 509 ? 1_555 OE1 ? A GLU 200 ? A GLU 200 ? 1_555 89.3  ? 
2  OE1 ? A GLU 197 ? A GLU 197 ? 1_555 CA ? K CA . ? A CA 509 ? 1_555 OE1 ? A GLN 217 ? A GLN 217 ? 1_555 58.6  ? 
3  OE1 ? A GLU 200 ? A GLU 200 ? 1_555 CA ? K CA . ? A CA 509 ? 1_555 OE1 ? A GLN 217 ? A GLN 217 ? 1_555 63.2  ? 
4  OE1 ? A GLU 197 ? A GLU 197 ? 1_555 CA ? K CA . ? A CA 509 ? 1_555 O   ? M SER .   ? A SER 511 ? 1_555 137.0 ? 
5  OE1 ? A GLU 200 ? A GLU 200 ? 1_555 CA ? K CA . ? A CA 509 ? 1_555 O   ? M SER .   ? A SER 511 ? 1_555 70.2  ? 
6  OE1 ? A GLN 217 ? A GLN 217 ? 1_555 CA ? K CA . ? A CA 509 ? 1_555 O   ? M SER .   ? A SER 511 ? 1_555 130.8 ? 
7  OE1 ? B GLU 197 ? B GLU 197 ? 1_555 CA ? X CA . ? B CA 510 ? 1_555 OE1 ? B GLU 200 ? B GLU 200 ? 1_555 90.4  ? 
8  OE1 ? B GLU 197 ? B GLU 197 ? 1_555 CA ? X CA . ? B CA 510 ? 1_555 OE1 ? B GLN 217 ? B GLN 217 ? 1_555 60.8  ? 
9  OE1 ? B GLU 200 ? B GLU 200 ? 1_555 CA ? X CA . ? B CA 510 ? 1_555 OE1 ? B GLN 217 ? B GLN 217 ? 1_555 61.2  ? 
10 OE1 ? B GLU 197 ? B GLU 197 ? 1_555 CA ? X CA . ? B CA 510 ? 1_555 O   ? Z SER .   ? B SER 512 ? 1_555 139.9 ? 
11 OE1 ? B GLU 200 ? B GLU 200 ? 1_555 CA ? X CA . ? B CA 510 ? 1_555 O   ? Z SER .   ? B SER 512 ? 1_555 69.0  ? 
12 OE1 ? B GLN 217 ? B GLN 217 ? 1_555 CA ? X CA . ? B CA 510 ? 1_555 O   ? Z SER .   ? B SER 512 ? 1_555 126.4 ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 ARG 95 A . ? ARG 95 A PRO 96 A ? PRO 96 A 1 -4.39 
2 ARG 95 B . ? ARG 95 B PRO 96 B ? PRO 96 B 1 -3.39 
# 
_pdbx_entry_details.entry_id                   9KQI 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
_pdbx_validate_torsion.id              1 
_pdbx_validate_torsion.PDB_model_num   1 
_pdbx_validate_torsion.auth_comp_id    SER 
_pdbx_validate_torsion.auth_asym_id    A 
_pdbx_validate_torsion.auth_seq_id     320 
_pdbx_validate_torsion.PDB_ins_code    ? 
_pdbx_validate_torsion.label_alt_id    ? 
_pdbx_validate_torsion.phi             -94.74 
_pdbx_validate_torsion.psi             -62.20 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9KQI 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9KQI 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.02 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               446795 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'cryoEM structure of PSS1 dimer' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9KQI 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9KQI 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9KQI 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1   ? A MET 1   
2   1 Y 1 A ALA 2   ? A ALA 2   
3   1 Y 1 A SER 3   ? A SER 3   
4   1 Y 1 A CYS 4   ? A CYS 4   
5   1 Y 1 A VAL 5   ? A VAL 5   
6   1 Y 1 A GLY 6   ? A GLY 6   
7   1 Y 1 A SER 7   ? A SER 7   
8   1 Y 1 A ARG 8   ? A ARG 8   
9   1 Y 1 A THR 9   ? A THR 9   
10  1 Y 1 A LEU 10  ? A LEU 10  
11  1 Y 1 A SER 11  ? A SER 11  
12  1 Y 1 A LYS 12  ? A LYS 12  
13  1 Y 1 A ASP 13  ? A ASP 13  
14  1 Y 1 A THR 141 ? A THR 141 
15  1 Y 1 A ARG 142 ? A ARG 142 
16  1 Y 1 A GLU 143 ? A GLU 143 
17  1 Y 1 A ALA 144 ? A ALA 144 
18  1 Y 1 A ASP 145 ? A ASP 145 
19  1 Y 1 A VAL 146 ? A VAL 146 
20  1 Y 1 A MET 147 ? A MET 147 
21  1 Y 1 A GLU 148 ? A GLU 148 
22  1 Y 1 A TYR 149 ? A TYR 149 
23  1 Y 1 A ALA 150 ? A ALA 150 
24  1 Y 1 A VAL 151 ? A VAL 151 
25  1 Y 1 A ASN 152 ? A ASN 152 
26  1 Y 1 A CYS 153 ? A CYS 153 
27  1 Y 1 A HIS 154 ? A HIS 154 
28  1 Y 1 A VAL 155 ? A VAL 155 
29  1 Y 1 A ILE 156 ? A ILE 156 
30  1 Y 1 A THR 157 ? A THR 157 
31  1 Y 1 A TRP 158 ? A TRP 158 
32  1 Y 1 A TYR 409 ? A TYR 409 
33  1 Y 1 A GLY 410 ? A GLY 410 
34  1 Y 1 A HIS 411 ? A HIS 411 
35  1 Y 1 A ARG 412 ? A ARG 412 
36  1 Y 1 A GLU 413 ? A GLU 413 
37  1 Y 1 A LYS 414 ? A LYS 414 
38  1 Y 1 A THR 415 ? A THR 415 
39  1 Y 1 A TYR 416 ? A TYR 416 
40  1 Y 1 A SER 417 ? A SER 417 
41  1 Y 1 A GLU 418 ? A GLU 418 
42  1 Y 1 A CYS 419 ? A CYS 419 
43  1 Y 1 A GLU 420 ? A GLU 420 
44  1 Y 1 A ASP 421 ? A ASP 421 
45  1 Y 1 A GLY 422 ? A GLY 422 
46  1 Y 1 A THR 423 ? A THR 423 
47  1 Y 1 A TYR 424 ? A TYR 424 
48  1 Y 1 A SER 425 ? A SER 425 
49  1 Y 1 A PRO 426 ? A PRO 426 
50  1 Y 1 A GLU 427 ? A GLU 427 
51  1 Y 1 A ILE 428 ? A ILE 428 
52  1 Y 1 A SER 429 ? A SER 429 
53  1 Y 1 A TRP 430 ? A TRP 430 
54  1 Y 1 A HIS 431 ? A HIS 431 
55  1 Y 1 A HIS 432 ? A HIS 432 
56  1 Y 1 A ARG 433 ? A ARG 433 
57  1 Y 1 A LYS 434 ? A LYS 434 
58  1 Y 1 A GLY 435 ? A GLY 435 
59  1 Y 1 A THR 436 ? A THR 436 
60  1 Y 1 A LYS 437 ? A LYS 437 
61  1 Y 1 A GLY 438 ? A GLY 438 
62  1 Y 1 A SER 439 ? A SER 439 
63  1 Y 1 A GLU 440 ? A GLU 440 
64  1 Y 1 A ASP 441 ? A ASP 441 
65  1 Y 1 A SER 442 ? A SER 442 
66  1 Y 1 A PRO 443 ? A PRO 443 
67  1 Y 1 A PRO 444 ? A PRO 444 
68  1 Y 1 A LYS 445 ? A LYS 445 
69  1 Y 1 A HIS 446 ? A HIS 446 
70  1 Y 1 A ALA 447 ? A ALA 447 
71  1 Y 1 A GLY 448 ? A GLY 448 
72  1 Y 1 A ASN 449 ? A ASN 449 
73  1 Y 1 A ASN 450 ? A ASN 450 
74  1 Y 1 A GLU 451 ? A GLU 451 
75  1 Y 1 A SER 452 ? A SER 452 
76  1 Y 1 A HIS 453 ? A HIS 453 
77  1 Y 1 A SER 454 ? A SER 454 
78  1 Y 1 A SER 455 ? A SER 455 
79  1 Y 1 A ARG 456 ? A ARG 456 
80  1 Y 1 A ARG 457 ? A ARG 457 
81  1 Y 1 A ARG 458 ? A ARG 458 
82  1 Y 1 A ASN 459 ? A ASN 459 
83  1 Y 1 A ARG 460 ? A ARG 460 
84  1 Y 1 A HIS 461 ? A HIS 461 
85  1 Y 1 A SER 462 ? A SER 462 
86  1 Y 1 A LYS 463 ? A LYS 463 
87  1 Y 1 A SER 464 ? A SER 464 
88  1 Y 1 A LYS 465 ? A LYS 465 
89  1 Y 1 A VAL 466 ? A VAL 466 
90  1 Y 1 A THR 467 ? A THR 467 
91  1 Y 1 A ASN 468 ? A ASN 468 
92  1 Y 1 A GLY 469 ? A GLY 469 
93  1 Y 1 A VAL 470 ? A VAL 470 
94  1 Y 1 A GLY 471 ? A GLY 471 
95  1 Y 1 A LYS 472 ? A LYS 472 
96  1 Y 1 A LYS 473 ? A LYS 473 
97  1 Y 1 B MET 1   ? B MET 1   
98  1 Y 1 B ALA 2   ? B ALA 2   
99  1 Y 1 B SER 3   ? B SER 3   
100 1 Y 1 B CYS 4   ? B CYS 4   
101 1 Y 1 B VAL 5   ? B VAL 5   
102 1 Y 1 B GLY 6   ? B GLY 6   
103 1 Y 1 B SER 7   ? B SER 7   
104 1 Y 1 B ARG 8   ? B ARG 8   
105 1 Y 1 B THR 9   ? B THR 9   
106 1 Y 1 B LEU 10  ? B LEU 10  
107 1 Y 1 B SER 11  ? B SER 11  
108 1 Y 1 B LYS 12  ? B LYS 12  
109 1 Y 1 B ASP 13  ? B ASP 13  
110 1 Y 1 B THR 141 ? B THR 141 
111 1 Y 1 B ARG 142 ? B ARG 142 
112 1 Y 1 B GLU 143 ? B GLU 143 
113 1 Y 1 B ALA 144 ? B ALA 144 
114 1 Y 1 B ASP 145 ? B ASP 145 
115 1 Y 1 B VAL 146 ? B VAL 146 
116 1 Y 1 B MET 147 ? B MET 147 
117 1 Y 1 B GLU 148 ? B GLU 148 
118 1 Y 1 B TYR 149 ? B TYR 149 
119 1 Y 1 B ALA 150 ? B ALA 150 
120 1 Y 1 B VAL 151 ? B VAL 151 
121 1 Y 1 B ASN 152 ? B ASN 152 
122 1 Y 1 B CYS 153 ? B CYS 153 
123 1 Y 1 B HIS 154 ? B HIS 154 
124 1 Y 1 B VAL 155 ? B VAL 155 
125 1 Y 1 B ILE 156 ? B ILE 156 
126 1 Y 1 B THR 157 ? B THR 157 
127 1 Y 1 B TRP 158 ? B TRP 158 
128 1 Y 1 B TYR 409 ? B TYR 409 
129 1 Y 1 B GLY 410 ? B GLY 410 
130 1 Y 1 B HIS 411 ? B HIS 411 
131 1 Y 1 B ARG 412 ? B ARG 412 
132 1 Y 1 B GLU 413 ? B GLU 413 
133 1 Y 1 B LYS 414 ? B LYS 414 
134 1 Y 1 B THR 415 ? B THR 415 
135 1 Y 1 B TYR 416 ? B TYR 416 
136 1 Y 1 B SER 417 ? B SER 417 
137 1 Y 1 B GLU 418 ? B GLU 418 
138 1 Y 1 B CYS 419 ? B CYS 419 
139 1 Y 1 B GLU 420 ? B GLU 420 
140 1 Y 1 B ASP 421 ? B ASP 421 
141 1 Y 1 B GLY 422 ? B GLY 422 
142 1 Y 1 B THR 423 ? B THR 423 
143 1 Y 1 B TYR 424 ? B TYR 424 
144 1 Y 1 B SER 425 ? B SER 425 
145 1 Y 1 B PRO 426 ? B PRO 426 
146 1 Y 1 B GLU 427 ? B GLU 427 
147 1 Y 1 B ILE 428 ? B ILE 428 
148 1 Y 1 B SER 429 ? B SER 429 
149 1 Y 1 B TRP 430 ? B TRP 430 
150 1 Y 1 B HIS 431 ? B HIS 431 
151 1 Y 1 B HIS 432 ? B HIS 432 
152 1 Y 1 B ARG 433 ? B ARG 433 
153 1 Y 1 B LYS 434 ? B LYS 434 
154 1 Y 1 B GLY 435 ? B GLY 435 
155 1 Y 1 B THR 436 ? B THR 436 
156 1 Y 1 B LYS 437 ? B LYS 437 
157 1 Y 1 B GLY 438 ? B GLY 438 
158 1 Y 1 B SER 439 ? B SER 439 
159 1 Y 1 B GLU 440 ? B GLU 440 
160 1 Y 1 B ASP 441 ? B ASP 441 
161 1 Y 1 B SER 442 ? B SER 442 
162 1 Y 1 B PRO 443 ? B PRO 443 
163 1 Y 1 B PRO 444 ? B PRO 444 
164 1 Y 1 B LYS 445 ? B LYS 445 
165 1 Y 1 B HIS 446 ? B HIS 446 
166 1 Y 1 B ALA 447 ? B ALA 447 
167 1 Y 1 B GLY 448 ? B GLY 448 
168 1 Y 1 B ASN 449 ? B ASN 449 
169 1 Y 1 B ASN 450 ? B ASN 450 
170 1 Y 1 B GLU 451 ? B GLU 451 
171 1 Y 1 B SER 452 ? B SER 452 
172 1 Y 1 B HIS 453 ? B HIS 453 
173 1 Y 1 B SER 454 ? B SER 454 
174 1 Y 1 B SER 455 ? B SER 455 
175 1 Y 1 B ARG 456 ? B ARG 456 
176 1 Y 1 B ARG 457 ? B ARG 457 
177 1 Y 1 B ARG 458 ? B ARG 458 
178 1 Y 1 B ASN 459 ? B ASN 459 
179 1 Y 1 B ARG 460 ? B ARG 460 
180 1 Y 1 B HIS 461 ? B HIS 461 
181 1 Y 1 B SER 462 ? B SER 462 
182 1 Y 1 B LYS 463 ? B LYS 463 
183 1 Y 1 B SER 464 ? B SER 464 
184 1 Y 1 B LYS 465 ? B LYS 465 
185 1 Y 1 B VAL 466 ? B VAL 466 
186 1 Y 1 B THR 467 ? B THR 467 
187 1 Y 1 B ASN 468 ? B ASN 468 
188 1 Y 1 B GLY 469 ? B GLY 469 
189 1 Y 1 B VAL 470 ? B VAL 470 
190 1 Y 1 B GLY 471 ? B GLY 471 
191 1 Y 1 B LYS 472 ? B LYS 472 
192 1 Y 1 B LYS 473 ? B LYS 473 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
C14 C01  C  N N 74  
C14 C02  C  N N 75  
C14 C03  C  N N 76  
C14 C04  C  N N 77  
C14 C05  C  N N 78  
C14 C06  C  N N 79  
C14 C07  C  N N 80  
C14 C08  C  N N 81  
C14 C09  C  N N 82  
C14 C10  C  N N 83  
C14 C11  C  N N 84  
C14 C12  C  N N 85  
C14 C13  C  N N 86  
C14 C14  C  N N 87  
C14 H011 H  N N 88  
C14 H012 H  N N 89  
C14 H013 H  N N 90  
C14 H021 H  N N 91  
C14 H022 H  N N 92  
C14 H031 H  N N 93  
C14 H032 H  N N 94  
C14 H041 H  N N 95  
C14 H042 H  N N 96  
C14 H051 H  N N 97  
C14 H052 H  N N 98  
C14 H061 H  N N 99  
C14 H062 H  N N 100 
C14 H071 H  N N 101 
C14 H072 H  N N 102 
C14 H081 H  N N 103 
C14 H082 H  N N 104 
C14 H091 H  N N 105 
C14 H092 H  N N 106 
C14 H101 H  N N 107 
C14 H102 H  N N 108 
C14 H111 H  N N 109 
C14 H112 H  N N 110 
C14 H121 H  N N 111 
C14 H122 H  N N 112 
C14 H131 H  N N 113 
C14 H132 H  N N 114 
C14 H141 H  N N 115 
C14 H142 H  N N 116 
C14 H143 H  N N 117 
CA  CA   CA N N 118 
CYS N    N  N N 119 
CYS CA   C  N R 120 
CYS C    C  N N 121 
CYS O    O  N N 122 
CYS CB   C  N N 123 
CYS SG   S  N N 124 
CYS OXT  O  N N 125 
CYS H    H  N N 126 
CYS H2   H  N N 127 
CYS HA   H  N N 128 
CYS HB2  H  N N 129 
CYS HB3  H  N N 130 
CYS HG   H  N N 131 
CYS HXT  H  N N 132 
D12 C1   C  N N 133 
D12 C2   C  N N 134 
D12 C3   C  N N 135 
D12 C4   C  N N 136 
D12 C5   C  N N 137 
D12 C6   C  N N 138 
D12 C7   C  N N 139 
D12 C8   C  N N 140 
D12 C9   C  N N 141 
D12 C10  C  N N 142 
D12 C11  C  N N 143 
D12 C12  C  N N 144 
D12 H11  H  N N 145 
D12 H12  H  N N 146 
D12 H13  H  N N 147 
D12 H21  H  N N 148 
D12 H22  H  N N 149 
D12 H31  H  N N 150 
D12 H32  H  N N 151 
D12 H41  H  N N 152 
D12 H42  H  N N 153 
D12 H51  H  N N 154 
D12 H52  H  N N 155 
D12 H61  H  N N 156 
D12 H62  H  N N 157 
D12 H71  H  N N 158 
D12 H72  H  N N 159 
D12 H81  H  N N 160 
D12 H82  H  N N 161 
D12 H91  H  N N 162 
D12 H92  H  N N 163 
D12 H101 H  N N 164 
D12 H102 H  N N 165 
D12 H111 H  N N 166 
D12 H112 H  N N 167 
D12 H121 H  N N 168 
D12 H122 H  N N 169 
D12 H123 H  N N 170 
GLN N    N  N N 171 
GLN CA   C  N S 172 
GLN C    C  N N 173 
GLN O    O  N N 174 
GLN CB   C  N N 175 
GLN CG   C  N N 176 
GLN CD   C  N N 177 
GLN OE1  O  N N 178 
GLN NE2  N  N N 179 
GLN OXT  O  N N 180 
GLN H    H  N N 181 
GLN H2   H  N N 182 
GLN HA   H  N N 183 
GLN HB2  H  N N 184 
GLN HB3  H  N N 185 
GLN HG2  H  N N 186 
GLN HG3  H  N N 187 
GLN HE21 H  N N 188 
GLN HE22 H  N N 189 
GLN HXT  H  N N 190 
GLU N    N  N N 191 
GLU CA   C  N S 192 
GLU C    C  N N 193 
GLU O    O  N N 194 
GLU CB   C  N N 195 
GLU CG   C  N N 196 
GLU CD   C  N N 197 
GLU OE1  O  N N 198 
GLU OE2  O  N N 199 
GLU OXT  O  N N 200 
GLU H    H  N N 201 
GLU H2   H  N N 202 
GLU HA   H  N N 203 
GLU HB2  H  N N 204 
GLU HB3  H  N N 205 
GLU HG2  H  N N 206 
GLU HG3  H  N N 207 
GLU HE2  H  N N 208 
GLU HXT  H  N N 209 
GLY N    N  N N 210 
GLY CA   C  N N 211 
GLY C    C  N N 212 
GLY O    O  N N 213 
GLY OXT  O  N N 214 
GLY H    H  N N 215 
GLY H2   H  N N 216 
GLY HA2  H  N N 217 
GLY HA3  H  N N 218 
GLY HXT  H  N N 219 
HIS N    N  N N 220 
HIS CA   C  N S 221 
HIS C    C  N N 222 
HIS O    O  N N 223 
HIS CB   C  N N 224 
HIS CG   C  Y N 225 
HIS ND1  N  Y N 226 
HIS CD2  C  Y N 227 
HIS CE1  C  Y N 228 
HIS NE2  N  Y N 229 
HIS OXT  O  N N 230 
HIS H    H  N N 231 
HIS H2   H  N N 232 
HIS HA   H  N N 233 
HIS HB2  H  N N 234 
HIS HB3  H  N N 235 
HIS HD1  H  N N 236 
HIS HD2  H  N N 237 
HIS HE1  H  N N 238 
HIS HE2  H  N N 239 
HIS HXT  H  N N 240 
ILE N    N  N N 241 
ILE CA   C  N S 242 
ILE C    C  N N 243 
ILE O    O  N N 244 
ILE CB   C  N S 245 
ILE CG1  C  N N 246 
ILE CG2  C  N N 247 
ILE CD1  C  N N 248 
ILE OXT  O  N N 249 
ILE H    H  N N 250 
ILE H2   H  N N 251 
ILE HA   H  N N 252 
ILE HB   H  N N 253 
ILE HG12 H  N N 254 
ILE HG13 H  N N 255 
ILE HG21 H  N N 256 
ILE HG22 H  N N 257 
ILE HG23 H  N N 258 
ILE HD11 H  N N 259 
ILE HD12 H  N N 260 
ILE HD13 H  N N 261 
ILE HXT  H  N N 262 
LBN C1   C  N N 263 
LBN N1   N  N N 264 
LBN P1   P  N N 265 
LBN C2   C  N R 266 
LBN C3   C  N N 267 
LBN C4   C  N N 268 
LBN C5   C  N N 269 
LBN C6   C  N N 270 
LBN O1   O  N N 271 
LBN C7   C  N N 272 
LBN C8   C  N N 273 
LBN C9   C  N N 274 
LBN O2   O  N N 275 
LBN C10  C  N N 276 
LBN C11  C  N N 277 
LBN C12  C  N N 278 
LBN O3   O  N N 279 
LBN C13  C  N N 280 
LBN C14  C  N N 281 
LBN C15  C  N N 282 
LBN O4   O  N N 283 
LBN C16  C  N N 284 
LBN C17  C  N N 285 
LBN C18  C  N N 286 
LBN C19  C  N N 287 
LBN C20  C  N N 288 
LBN C21  C  N N 289 
LBN C22  C  N N 290 
LBN C23  C  N N 291 
LBN C24  C  N N 292 
LBN C25  C  N N 293 
LBN O5   O  N N 294 
LBN C26  C  N N 295 
LBN O6   O  N N 296 
LBN C27  C  N N 297 
LBN C28  C  N N 298 
LBN C29  C  N N 299 
LBN C30  C  N N 300 
LBN C31  C  N N 301 
LBN C32  C  N N 302 
LBN C33  C  N N 303 
LBN C34  C  N N 304 
LBN O7   O  N N 305 
LBN C35  C  N N 306 
LBN O8   O  N N 307 
LBN C36  C  N N 308 
LBN C37  C  N N 309 
LBN C38  C  N N 310 
LBN C39  C  N N 311 
LBN C40  C  N N 312 
LBN C41  C  N N 313 
LBN C42  C  N N 314 
LBN H1   H  N N 315 
LBN H2   H  N N 316 
LBN H3   H  N N 317 
LBN H4   H  N N 318 
LBN H5   H  N N 319 
LBN H6   H  N N 320 
LBN H7   H  N N 321 
LBN H8   H  N N 322 
LBN H9   H  N N 323 
LBN H10  H  N N 324 
LBN H11  H  N N 325 
LBN H12  H  N N 326 
LBN H13  H  N N 327 
LBN H14  H  N N 328 
LBN H15  H  N N 329 
LBN H16  H  N N 330 
LBN H17  H  N N 331 
LBN H18  H  N N 332 
LBN H19  H  N N 333 
LBN H20  H  N N 334 
LBN H21  H  N N 335 
LBN H22  H  N N 336 
LBN H23  H  N N 337 
LBN H24  H  N N 338 
LBN H25  H  N N 339 
LBN H26  H  N N 340 
LBN H27  H  N N 341 
LBN H28  H  N N 342 
LBN H30  H  N N 343 
LBN H31  H  N N 344 
LBN H32  H  N N 345 
LBN H33  H  N N 346 
LBN H34  H  N N 347 
LBN H35  H  N N 348 
LBN H36  H  N N 349 
LBN H37  H  N N 350 
LBN H38  H  N N 351 
LBN H39  H  N N 352 
LBN H40  H  N N 353 
LBN H41  H  N N 354 
LBN H42  H  N N 355 
LBN H43  H  N N 356 
LBN H44  H  N N 357 
LBN H45  H  N N 358 
LBN H46  H  N N 359 
LBN H47  H  N N 360 
LBN H48  H  N N 361 
LBN H49  H  N N 362 
LBN H50  H  N N 363 
LBN H51  H  N N 364 
LBN H52  H  N N 365 
LBN H53  H  N N 366 
LBN H54  H  N N 367 
LBN H55  H  N N 368 
LBN H56  H  N N 369 
LBN H57  H  N N 370 
LBN H58  H  N N 371 
LBN H59  H  N N 372 
LBN H60  H  N N 373 
LBN H61  H  N N 374 
LBN H62  H  N N 375 
LBN H63  H  N N 376 
LBN H64  H  N N 377 
LBN H65  H  N N 378 
LBN H66  H  N N 379 
LBN H67  H  N N 380 
LBN H68  H  N N 381 
LBN H69  H  N N 382 
LBN H70  H  N N 383 
LBN H71  H  N N 384 
LBN H72  H  N N 385 
LBN H73  H  N N 386 
LBN H74  H  N N 387 
LBN H75  H  N N 388 
LBN H76  H  N N 389 
LBN H77  H  N N 390 
LBN H78  H  N N 391 
LBN H79  H  N N 392 
LBN H80  H  N N 393 
LBN H81  H  N N 394 
LBN H82  H  N N 395 
LBN H83  H  N N 396 
LEU N    N  N N 397 
LEU CA   C  N S 398 
LEU C    C  N N 399 
LEU O    O  N N 400 
LEU CB   C  N N 401 
LEU CG   C  N N 402 
LEU CD1  C  N N 403 
LEU CD2  C  N N 404 
LEU OXT  O  N N 405 
LEU H    H  N N 406 
LEU H2   H  N N 407 
LEU HA   H  N N 408 
LEU HB2  H  N N 409 
LEU HB3  H  N N 410 
LEU HG   H  N N 411 
LEU HD11 H  N N 412 
LEU HD12 H  N N 413 
LEU HD13 H  N N 414 
LEU HD21 H  N N 415 
LEU HD22 H  N N 416 
LEU HD23 H  N N 417 
LEU HXT  H  N N 418 
LYS N    N  N N 419 
LYS CA   C  N S 420 
LYS C    C  N N 421 
LYS O    O  N N 422 
LYS CB   C  N N 423 
LYS CG   C  N N 424 
LYS CD   C  N N 425 
LYS CE   C  N N 426 
LYS NZ   N  N N 427 
LYS OXT  O  N N 428 
LYS H    H  N N 429 
LYS H2   H  N N 430 
LYS HA   H  N N 431 
LYS HB2  H  N N 432 
LYS HB3  H  N N 433 
LYS HG2  H  N N 434 
LYS HG3  H  N N 435 
LYS HD2  H  N N 436 
LYS HD3  H  N N 437 
LYS HE2  H  N N 438 
LYS HE3  H  N N 439 
LYS HZ1  H  N N 440 
LYS HZ2  H  N N 441 
LYS HZ3  H  N N 442 
LYS HXT  H  N N 443 
MET N    N  N N 444 
MET CA   C  N S 445 
MET C    C  N N 446 
MET O    O  N N 447 
MET CB   C  N N 448 
MET CG   C  N N 449 
MET SD   S  N N 450 
MET CE   C  N N 451 
MET OXT  O  N N 452 
MET H    H  N N 453 
MET H2   H  N N 454 
MET HA   H  N N 455 
MET HB2  H  N N 456 
MET HB3  H  N N 457 
MET HG2  H  N N 458 
MET HG3  H  N N 459 
MET HE1  H  N N 460 
MET HE2  H  N N 461 
MET HE3  H  N N 462 
MET HXT  H  N N 463 
PHE N    N  N N 464 
PHE CA   C  N S 465 
PHE C    C  N N 466 
PHE O    O  N N 467 
PHE CB   C  N N 468 
PHE CG   C  Y N 469 
PHE CD1  C  Y N 470 
PHE CD2  C  Y N 471 
PHE CE1  C  Y N 472 
PHE CE2  C  Y N 473 
PHE CZ   C  Y N 474 
PHE OXT  O  N N 475 
PHE H    H  N N 476 
PHE H2   H  N N 477 
PHE HA   H  N N 478 
PHE HB2  H  N N 479 
PHE HB3  H  N N 480 
PHE HD1  H  N N 481 
PHE HD2  H  N N 482 
PHE HE1  H  N N 483 
PHE HE2  H  N N 484 
PHE HZ   H  N N 485 
PHE HXT  H  N N 486 
PRO N    N  N N 487 
PRO CA   C  N S 488 
PRO C    C  N N 489 
PRO O    O  N N 490 
PRO CB   C  N N 491 
PRO CG   C  N N 492 
PRO CD   C  N N 493 
PRO OXT  O  N N 494 
PRO H    H  N N 495 
PRO HA   H  N N 496 
PRO HB2  H  N N 497 
PRO HB3  H  N N 498 
PRO HG2  H  N N 499 
PRO HG3  H  N N 500 
PRO HD2  H  N N 501 
PRO HD3  H  N N 502 
PRO HXT  H  N N 503 
PSF O2   O  N N 504 
PSF O1   O  N N 505 
PSF P    P  N R 506 
PSF O4   O  N N 507 
PSF O3   O  N N 508 
PSF C2   C  N N 509 
PSF C3   C  N N 510 
PSF O11  O  N N 511 
PSF O12  O  N N 512 
PSF C1   C  N N 513 
PSF C4   C  N N 514 
PSF C5   C  N N 515 
PSF O51  O  N N 516 
PSF O52  O  N N 517 
PSF C6   C  N N 518 
PSF C7   C  N N 519 
PSF C13  C  N N 520 
PSF C14  C  N N 521 
PSF C15  C  N N 522 
PSF N    N  N N 523 
PSF CA   C  N S 524 
PSF CB   C  N N 525 
PSF C    C  N N 526 
PSF OT1  O  N N 527 
PSF OT2  O  N N 528 
PSF C8   C  N N 529 
PSF C9   C  N N 530 
PSF C10  C  N N 531 
PSF C16  C  N N 532 
PSF C17  C  N N 533 
PSF HO3  H  N N 534 
PSF H21  H  N N 535 
PSF H22  H  N N 536 
PSF H31  H  N N 537 
PSF H41  H  N N 538 
PSF H42  H  N N 539 
PSF H61  H  N N 540 
PSF H62  H  N N 541 
PSF H71  H  N N 542 
PSF H72  H  N N 543 
PSF H131 H  N N 544 
PSF H132 H  N N 545 
PSF H141 H  N N 546 
PSF H142 H  N N 547 
PSF H151 H  N N 548 
PSF H152 H  N N 549 
PSF H1   H  N N 550 
PSF H2   H  N N 551 
PSF HA   H  N N 552 
PSF HB1  H  N N 553 
PSF HB2  H  N N 554 
PSF HXT  H  N N 555 
PSF H81  H  N N 556 
PSF H82  H  N N 557 
PSF H91  H  N N 558 
PSF H92  H  N N 559 
PSF H101 H  N N 560 
PSF H102 H  N N 561 
PSF H103 H  N N 562 
PSF H161 H  N N 563 
PSF H162 H  N N 564 
PSF H171 H  N N 565 
PSF H172 H  N N 566 
PSF H173 H  N N 567 
SER N    N  N N 568 
SER CA   C  N S 569 
SER C    C  N N 570 
SER O    O  N N 571 
SER CB   C  N N 572 
SER OG   O  N N 573 
SER OXT  O  N N 574 
SER H    H  N N 575 
SER H2   H  N N 576 
SER HA   H  N N 577 
SER HB2  H  N N 578 
SER HB3  H  N N 579 
SER HG   H  N N 580 
SER HXT  H  N N 581 
T7X C1   C  N N 582 
T7X O1   O  N N 583 
T7X P1   P  N N 584 
T7X C2   C  N R 585 
T7X O2   O  N N 586 
T7X C3   C  N S 587 
T7X O3   O  N N 588 
T7X C4   C  N N 589 
T7X O4   O  N N 590 
T7X C5   C  N R 591 
T7X O5   O  N N 592 
T7X C6   C  N R 593 
T7X O6   O  N N 594 
T7X C7   C  N N 595 
T7X C8   C  N R 596 
T7X C9   C  N N 597 
T7X C10  C  N N 598 
T7X C11  C  N N 599 
T7X O11  O  N N 600 
T7X C12  C  N N 601 
T7X O12  O  N N 602 
T7X C13  C  N N 603 
T7X O13  O  N N 604 
T7X C14  C  N N 605 
T7X C15  C  N N 606 
T7X C16  C  N N 607 
T7X O16  O  N N 608 
T7X C17  C  N N 609 
T7X O17  O  N N 610 
T7X C18  C  N N 611 
T7X O18  O  N N 612 
T7X C19  C  N N 613 
T7X O19  O  N N 614 
T7X C20  C  N N 615 
T7X C21  C  N N 616 
T7X C22  C  N N 617 
T7X C23  C  N N 618 
T7X C24  C  N N 619 
T7X C25  C  N N 620 
T7X C26  C  N N 621 
T7X C27  C  N N 622 
T7X C31  C  N N 623 
T7X C32  C  N N 624 
T7X C33  C  N N 625 
T7X C34  C  N N 626 
T7X C35  C  N N 627 
T7X C36  C  N N 628 
T7X C37  C  N N 629 
T7X C38  C  N N 630 
T7X C39  C  N N 631 
T7X C40  C  N N 632 
T7X C41  C  N N 633 
T7X H1   H  N N 634 
T7X H2   H  N N 635 
T7X H3   H  N N 636 
T7X H4   H  N N 637 
T7X H5   H  N N 638 
T7X H6   H  N N 639 
T7X H7   H  N N 640 
T7X H8   H  N N 641 
T7X H9   H  N N 642 
T7X H10  H  N N 643 
T7X H11  H  N N 644 
T7X H12  H  N N 645 
T7X H13  H  N N 646 
T7X H14  H  N N 647 
T7X H15  H  N N 648 
T7X H16  H  N N 649 
T7X H17  H  N N 650 
T7X H18  H  N N 651 
T7X H19  H  N N 652 
T7X H20  H  N N 653 
T7X H21  H  N N 654 
T7X H22  H  N N 655 
T7X H23  H  N N 656 
T7X H24  H  N N 657 
T7X H25  H  N N 658 
T7X H26  H  N N 659 
T7X H27  H  N N 660 
T7X H28  H  N N 661 
T7X H29  H  N N 662 
T7X H30  H  N N 663 
T7X H32  H  N N 664 
T7X H34  H  N N 665 
T7X H36  H  N N 666 
T7X H38  H  N N 667 
T7X H40  H  N N 668 
T7X H42  H  N N 669 
T7X H43  H  N N 670 
T7X H44  H  N N 671 
T7X H45  H  N N 672 
T7X H47  H  N N 673 
T7X H48  H  N N 674 
T7X H49  H  N N 675 
T7X H50  H  N N 676 
T7X H51  H  N N 677 
T7X H52  H  N N 678 
T7X H53  H  N N 679 
T7X H54  H  N N 680 
T7X H55  H  N N 681 
T7X H56  H  N N 682 
T7X H57  H  N N 683 
T7X H58  H  N N 684 
T7X H59  H  N N 685 
T7X H60  H  N N 686 
T7X H61  H  N N 687 
T7X H62  H  N N 688 
T7X H63  H  N N 689 
T7X H64  H  N N 690 
T7X H65  H  N N 691 
T7X H66  H  N N 692 
T7X H67  H  N N 693 
T7X H68  H  N N 694 
T7X C28  C  N N 695 
T7X C29  C  N N 696 
T7X C30  C  N N 697 
T7X C42  C  N N 698 
T7X C43  C  N N 699 
T7X C44  C  N N 700 
T7X C45  C  N N 701 
T7X C46  C  N N 702 
T7X H31  H  N N 703 
T7X H33  H  N N 704 
T7X H35  H  N N 705 
T7X H37  H  N N 706 
T7X H39  H  N N 707 
T7X H41  H  N N 708 
T7X H46  H  N N 709 
T7X H69  H  N N 710 
T7X H70  H  N N 711 
T7X H71  H  N N 712 
T7X H72  H  N N 713 
T7X H73  H  N N 714 
T7X H74  H  N N 715 
T7X H75  H  N N 716 
T7X H76  H  N N 717 
T7X H77  H  N N 718 
T7X H78  H  N N 719 
T7X H79  H  N N 720 
T7X H80  H  N N 721 
T7X C47  C  N N 722 
T7X H81  H  N N 723 
T7X H82  H  N N 724 
T7X H83  H  N N 725 
THR N    N  N N 726 
THR CA   C  N S 727 
THR C    C  N N 728 
THR O    O  N N 729 
THR CB   C  N R 730 
THR OG1  O  N N 731 
THR CG2  C  N N 732 
THR OXT  O  N N 733 
THR H    H  N N 734 
THR H2   H  N N 735 
THR HA   H  N N 736 
THR HB   H  N N 737 
THR HG1  H  N N 738 
THR HG21 H  N N 739 
THR HG22 H  N N 740 
THR HG23 H  N N 741 
THR HXT  H  N N 742 
TRP N    N  N N 743 
TRP CA   C  N S 744 
TRP C    C  N N 745 
TRP O    O  N N 746 
TRP CB   C  N N 747 
TRP CG   C  Y N 748 
TRP CD1  C  Y N 749 
TRP CD2  C  Y N 750 
TRP NE1  N  Y N 751 
TRP CE2  C  Y N 752 
TRP CE3  C  Y N 753 
TRP CZ2  C  Y N 754 
TRP CZ3  C  Y N 755 
TRP CH2  C  Y N 756 
TRP OXT  O  N N 757 
TRP H    H  N N 758 
TRP H2   H  N N 759 
TRP HA   H  N N 760 
TRP HB2  H  N N 761 
TRP HB3  H  N N 762 
TRP HD1  H  N N 763 
TRP HE1  H  N N 764 
TRP HE3  H  N N 765 
TRP HZ2  H  N N 766 
TRP HZ3  H  N N 767 
TRP HH2  H  N N 768 
TRP HXT  H  N N 769 
TYR N    N  N N 770 
TYR CA   C  N S 771 
TYR C    C  N N 772 
TYR O    O  N N 773 
TYR CB   C  N N 774 
TYR CG   C  Y N 775 
TYR CD1  C  Y N 776 
TYR CD2  C  Y N 777 
TYR CE1  C  Y N 778 
TYR CE2  C  Y N 779 
TYR CZ   C  Y N 780 
TYR OH   O  N N 781 
TYR OXT  O  N N 782 
TYR H    H  N N 783 
TYR H2   H  N N 784 
TYR HA   H  N N 785 
TYR HB2  H  N N 786 
TYR HB3  H  N N 787 
TYR HD1  H  N N 788 
TYR HD2  H  N N 789 
TYR HE1  H  N N 790 
TYR HE2  H  N N 791 
TYR HH   H  N N 792 
TYR HXT  H  N N 793 
VAL N    N  N N 794 
VAL CA   C  N S 795 
VAL C    C  N N 796 
VAL O    O  N N 797 
VAL CB   C  N N 798 
VAL CG1  C  N N 799 
VAL CG2  C  N N 800 
VAL OXT  O  N N 801 
VAL H    H  N N 802 
VAL H2   H  N N 803 
VAL HA   H  N N 804 
VAL HB   H  N N 805 
VAL HG11 H  N N 806 
VAL HG12 H  N N 807 
VAL HG13 H  N N 808 
VAL HG21 H  N N 809 
VAL HG22 H  N N 810 
VAL HG23 H  N N 811 
VAL HXT  H  N N 812 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
C14 C01 C02  sing N N 70  
C14 C01 H011 sing N N 71  
C14 C01 H012 sing N N 72  
C14 C01 H013 sing N N 73  
C14 C02 C03  sing N N 74  
C14 C02 H021 sing N N 75  
C14 C02 H022 sing N N 76  
C14 C03 C04  sing N N 77  
C14 C03 H031 sing N N 78  
C14 C03 H032 sing N N 79  
C14 C04 C05  sing N N 80  
C14 C04 H041 sing N N 81  
C14 C04 H042 sing N N 82  
C14 C05 C06  sing N N 83  
C14 C05 H051 sing N N 84  
C14 C05 H052 sing N N 85  
C14 C06 C07  sing N N 86  
C14 C06 H061 sing N N 87  
C14 C06 H062 sing N N 88  
C14 C07 C08  sing N N 89  
C14 C07 H071 sing N N 90  
C14 C07 H072 sing N N 91  
C14 C08 C09  sing N N 92  
C14 C08 H081 sing N N 93  
C14 C08 H082 sing N N 94  
C14 C09 C10  sing N N 95  
C14 C09 H091 sing N N 96  
C14 C09 H092 sing N N 97  
C14 C10 C11  sing N N 98  
C14 C10 H101 sing N N 99  
C14 C10 H102 sing N N 100 
C14 C11 C12  sing N N 101 
C14 C11 H111 sing N N 102 
C14 C11 H112 sing N N 103 
C14 C12 C13  sing N N 104 
C14 C12 H121 sing N N 105 
C14 C12 H122 sing N N 106 
C14 C13 C14  sing N N 107 
C14 C13 H131 sing N N 108 
C14 C13 H132 sing N N 109 
C14 C14 H141 sing N N 110 
C14 C14 H142 sing N N 111 
C14 C14 H143 sing N N 112 
CYS N   CA   sing N N 113 
CYS N   H    sing N N 114 
CYS N   H2   sing N N 115 
CYS CA  C    sing N N 116 
CYS CA  CB   sing N N 117 
CYS CA  HA   sing N N 118 
CYS C   O    doub N N 119 
CYS C   OXT  sing N N 120 
CYS CB  SG   sing N N 121 
CYS CB  HB2  sing N N 122 
CYS CB  HB3  sing N N 123 
CYS SG  HG   sing N N 124 
CYS OXT HXT  sing N N 125 
D12 C1  C2   sing N N 126 
D12 C1  H11  sing N N 127 
D12 C1  H12  sing N N 128 
D12 C1  H13  sing N N 129 
D12 C2  C3   sing N N 130 
D12 C2  H21  sing N N 131 
D12 C2  H22  sing N N 132 
D12 C3  C4   sing N N 133 
D12 C3  H31  sing N N 134 
D12 C3  H32  sing N N 135 
D12 C4  C5   sing N N 136 
D12 C4  H41  sing N N 137 
D12 C4  H42  sing N N 138 
D12 C5  C6   sing N N 139 
D12 C5  H51  sing N N 140 
D12 C5  H52  sing N N 141 
D12 C6  C7   sing N N 142 
D12 C6  H61  sing N N 143 
D12 C6  H62  sing N N 144 
D12 C7  C8   sing N N 145 
D12 C7  H71  sing N N 146 
D12 C7  H72  sing N N 147 
D12 C8  C9   sing N N 148 
D12 C8  H81  sing N N 149 
D12 C8  H82  sing N N 150 
D12 C9  C10  sing N N 151 
D12 C9  H91  sing N N 152 
D12 C9  H92  sing N N 153 
D12 C10 C11  sing N N 154 
D12 C10 H101 sing N N 155 
D12 C10 H102 sing N N 156 
D12 C11 C12  sing N N 157 
D12 C11 H111 sing N N 158 
D12 C11 H112 sing N N 159 
D12 C12 H121 sing N N 160 
D12 C12 H122 sing N N 161 
D12 C12 H123 sing N N 162 
GLN N   CA   sing N N 163 
GLN N   H    sing N N 164 
GLN N   H2   sing N N 165 
GLN CA  C    sing N N 166 
GLN CA  CB   sing N N 167 
GLN CA  HA   sing N N 168 
GLN C   O    doub N N 169 
GLN C   OXT  sing N N 170 
GLN CB  CG   sing N N 171 
GLN CB  HB2  sing N N 172 
GLN CB  HB3  sing N N 173 
GLN CG  CD   sing N N 174 
GLN CG  HG2  sing N N 175 
GLN CG  HG3  sing N N 176 
GLN CD  OE1  doub N N 177 
GLN CD  NE2  sing N N 178 
GLN NE2 HE21 sing N N 179 
GLN NE2 HE22 sing N N 180 
GLN OXT HXT  sing N N 181 
GLU N   CA   sing N N 182 
GLU N   H    sing N N 183 
GLU N   H2   sing N N 184 
GLU CA  C    sing N N 185 
GLU CA  CB   sing N N 186 
GLU CA  HA   sing N N 187 
GLU C   O    doub N N 188 
GLU C   OXT  sing N N 189 
GLU CB  CG   sing N N 190 
GLU CB  HB2  sing N N 191 
GLU CB  HB3  sing N N 192 
GLU CG  CD   sing N N 193 
GLU CG  HG2  sing N N 194 
GLU CG  HG3  sing N N 195 
GLU CD  OE1  doub N N 196 
GLU CD  OE2  sing N N 197 
GLU OE2 HE2  sing N N 198 
GLU OXT HXT  sing N N 199 
GLY N   CA   sing N N 200 
GLY N   H    sing N N 201 
GLY N   H2   sing N N 202 
GLY CA  C    sing N N 203 
GLY CA  HA2  sing N N 204 
GLY CA  HA3  sing N N 205 
GLY C   O    doub N N 206 
GLY C   OXT  sing N N 207 
GLY OXT HXT  sing N N 208 
HIS N   CA   sing N N 209 
HIS N   H    sing N N 210 
HIS N   H2   sing N N 211 
HIS CA  C    sing N N 212 
HIS CA  CB   sing N N 213 
HIS CA  HA   sing N N 214 
HIS C   O    doub N N 215 
HIS C   OXT  sing N N 216 
HIS CB  CG   sing N N 217 
HIS CB  HB2  sing N N 218 
HIS CB  HB3  sing N N 219 
HIS CG  ND1  sing Y N 220 
HIS CG  CD2  doub Y N 221 
HIS ND1 CE1  doub Y N 222 
HIS ND1 HD1  sing N N 223 
HIS CD2 NE2  sing Y N 224 
HIS CD2 HD2  sing N N 225 
HIS CE1 NE2  sing Y N 226 
HIS CE1 HE1  sing N N 227 
HIS NE2 HE2  sing N N 228 
HIS OXT HXT  sing N N 229 
ILE N   CA   sing N N 230 
ILE N   H    sing N N 231 
ILE N   H2   sing N N 232 
ILE CA  C    sing N N 233 
ILE CA  CB   sing N N 234 
ILE CA  HA   sing N N 235 
ILE C   O    doub N N 236 
ILE C   OXT  sing N N 237 
ILE CB  CG1  sing N N 238 
ILE CB  CG2  sing N N 239 
ILE CB  HB   sing N N 240 
ILE CG1 CD1  sing N N 241 
ILE CG1 HG12 sing N N 242 
ILE CG1 HG13 sing N N 243 
ILE CG2 HG21 sing N N 244 
ILE CG2 HG22 sing N N 245 
ILE CG2 HG23 sing N N 246 
ILE CD1 HD11 sing N N 247 
ILE CD1 HD12 sing N N 248 
ILE CD1 HD13 sing N N 249 
ILE OXT HXT  sing N N 250 
LBN C12 N1   sing N N 251 
LBN O3  P1   sing N N 252 
LBN O2  C9   sing N N 253 
LBN O2  P1   sing N N 254 
LBN C9  C6   sing N N 255 
LBN O4  P1   doub N N 256 
LBN P1  O1   sing N N 257 
LBN C6  N1   sing N N 258 
LBN N1  C15  sing N N 259 
LBN N1  C18  sing N N 260 
LBN O1  C1   sing N N 261 
LBN C2  C1   sing N N 262 
LBN C2  C3   sing N N 263 
LBN C2  O7   sing N N 264 
LBN C3  O5   sing N N 265 
LBN O6  C25  doub N N 266 
LBN O5  C25  sing N N 267 
LBN O7  C34  sing N N 268 
LBN C25 C26  sing N N 269 
LBN C34 C35  sing N N 270 
LBN C34 O8   doub N N 271 
LBN C26 C27  sing N N 272 
LBN C35 C36  sing N N 273 
LBN C27 C28  sing N N 274 
LBN C36 C37  sing N N 275 
LBN C28 C29  sing N N 276 
LBN C37 C38  sing N N 277 
LBN C29 C30  sing N N 278 
LBN C39 C38  sing N N 279 
LBN C39 C40  sing N N 280 
LBN C41 C40  sing N N 281 
LBN C41 C42  sing N N 282 
LBN C30 C31  sing N N 283 
LBN C42 C5   doub N Z 284 
LBN C31 C32  sing N N 285 
LBN C5  C8   sing N N 286 
LBN C8  C11  sing N N 287 
LBN C32 C33  sing N N 288 
LBN C11 C14  sing N N 289 
LBN C33 C4   sing N N 290 
LBN C14 C17  sing N N 291 
LBN C4  C7   sing N N 292 
LBN C17 C20  sing N N 293 
LBN C7  C10  sing N N 294 
LBN C20 C22  sing N N 295 
LBN C10 C13  sing N N 296 
LBN C22 C23  sing N N 297 
LBN C13 C16  sing N N 298 
LBN C23 C24  sing N N 299 
LBN C16 C19  sing N N 300 
LBN C19 C21  sing N N 301 
LBN C1  H1   sing N N 302 
LBN C1  H2   sing N N 303 
LBN C2  H3   sing N N 304 
LBN C3  H4   sing N N 305 
LBN C3  H5   sing N N 306 
LBN C4  H6   sing N N 307 
LBN C4  H7   sing N N 308 
LBN C5  H8   sing N N 309 
LBN C6  H9   sing N N 310 
LBN C6  H10  sing N N 311 
LBN C7  H11  sing N N 312 
LBN C7  H12  sing N N 313 
LBN C8  H13  sing N N 314 
LBN C8  H14  sing N N 315 
LBN C9  H15  sing N N 316 
LBN C9  H16  sing N N 317 
LBN C10 H17  sing N N 318 
LBN C10 H18  sing N N 319 
LBN C11 H19  sing N N 320 
LBN C12 H20  sing N N 321 
LBN C12 H21  sing N N 322 
LBN C12 H22  sing N N 323 
LBN C13 H23  sing N N 324 
LBN C13 H24  sing N N 325 
LBN C14 H25  sing N N 326 
LBN C15 H26  sing N N 327 
LBN C15 H27  sing N N 328 
LBN C15 H28  sing N N 329 
LBN C16 H30  sing N N 330 
LBN C16 H31  sing N N 331 
LBN C17 H32  sing N N 332 
LBN C17 H33  sing N N 333 
LBN C18 H34  sing N N 334 
LBN C18 H35  sing N N 335 
LBN C18 H36  sing N N 336 
LBN C19 H37  sing N N 337 
LBN C19 H38  sing N N 338 
LBN C20 H39  sing N N 339 
LBN C20 H40  sing N N 340 
LBN C21 H41  sing N N 341 
LBN C21 H42  sing N N 342 
LBN C21 H43  sing N N 343 
LBN C22 H44  sing N N 344 
LBN C22 H45  sing N N 345 
LBN C23 H46  sing N N 346 
LBN C23 H47  sing N N 347 
LBN C24 H48  sing N N 348 
LBN C24 H49  sing N N 349 
LBN C24 H50  sing N N 350 
LBN C26 H51  sing N N 351 
LBN C26 H52  sing N N 352 
LBN C27 H53  sing N N 353 
LBN C27 H54  sing N N 354 
LBN C28 H55  sing N N 355 
LBN C28 H56  sing N N 356 
LBN C29 H57  sing N N 357 
LBN C29 H58  sing N N 358 
LBN C30 H59  sing N N 359 
LBN C30 H60  sing N N 360 
LBN C31 H61  sing N N 361 
LBN C31 H62  sing N N 362 
LBN C32 H63  sing N N 363 
LBN C32 H64  sing N N 364 
LBN C33 H65  sing N N 365 
LBN C33 H66  sing N N 366 
LBN C35 H67  sing N N 367 
LBN C35 H68  sing N N 368 
LBN C36 H69  sing N N 369 
LBN C36 H70  sing N N 370 
LBN C37 H71  sing N N 371 
LBN C37 H72  sing N N 372 
LBN C38 H73  sing N N 373 
LBN C38 H74  sing N N 374 
LBN C39 H75  sing N N 375 
LBN C40 H76  sing N N 376 
LBN C41 H77  sing N N 377 
LBN C41 H78  sing N N 378 
LBN C42 H79  sing N N 379 
LBN C11 H80  sing N N 380 
LBN C14 H81  sing N N 381 
LBN C39 H82  sing N N 382 
LBN C40 H83  sing N N 383 
LEU N   CA   sing N N 384 
LEU N   H    sing N N 385 
LEU N   H2   sing N N 386 
LEU CA  C    sing N N 387 
LEU CA  CB   sing N N 388 
LEU CA  HA   sing N N 389 
LEU C   O    doub N N 390 
LEU C   OXT  sing N N 391 
LEU CB  CG   sing N N 392 
LEU CB  HB2  sing N N 393 
LEU CB  HB3  sing N N 394 
LEU CG  CD1  sing N N 395 
LEU CG  CD2  sing N N 396 
LEU CG  HG   sing N N 397 
LEU CD1 HD11 sing N N 398 
LEU CD1 HD12 sing N N 399 
LEU CD1 HD13 sing N N 400 
LEU CD2 HD21 sing N N 401 
LEU CD2 HD22 sing N N 402 
LEU CD2 HD23 sing N N 403 
LEU OXT HXT  sing N N 404 
LYS N   CA   sing N N 405 
LYS N   H    sing N N 406 
LYS N   H2   sing N N 407 
LYS CA  C    sing N N 408 
LYS CA  CB   sing N N 409 
LYS CA  HA   sing N N 410 
LYS C   O    doub N N 411 
LYS C   OXT  sing N N 412 
LYS CB  CG   sing N N 413 
LYS CB  HB2  sing N N 414 
LYS CB  HB3  sing N N 415 
LYS CG  CD   sing N N 416 
LYS CG  HG2  sing N N 417 
LYS CG  HG3  sing N N 418 
LYS CD  CE   sing N N 419 
LYS CD  HD2  sing N N 420 
LYS CD  HD3  sing N N 421 
LYS CE  NZ   sing N N 422 
LYS CE  HE2  sing N N 423 
LYS CE  HE3  sing N N 424 
LYS NZ  HZ1  sing N N 425 
LYS NZ  HZ2  sing N N 426 
LYS NZ  HZ3  sing N N 427 
LYS OXT HXT  sing N N 428 
MET N   CA   sing N N 429 
MET N   H    sing N N 430 
MET N   H2   sing N N 431 
MET CA  C    sing N N 432 
MET CA  CB   sing N N 433 
MET CA  HA   sing N N 434 
MET C   O    doub N N 435 
MET C   OXT  sing N N 436 
MET CB  CG   sing N N 437 
MET CB  HB2  sing N N 438 
MET CB  HB3  sing N N 439 
MET CG  SD   sing N N 440 
MET CG  HG2  sing N N 441 
MET CG  HG3  sing N N 442 
MET SD  CE   sing N N 443 
MET CE  HE1  sing N N 444 
MET CE  HE2  sing N N 445 
MET CE  HE3  sing N N 446 
MET OXT HXT  sing N N 447 
PHE N   CA   sing N N 448 
PHE N   H    sing N N 449 
PHE N   H2   sing N N 450 
PHE CA  C    sing N N 451 
PHE CA  CB   sing N N 452 
PHE CA  HA   sing N N 453 
PHE C   O    doub N N 454 
PHE C   OXT  sing N N 455 
PHE CB  CG   sing N N 456 
PHE CB  HB2  sing N N 457 
PHE CB  HB3  sing N N 458 
PHE CG  CD1  doub Y N 459 
PHE CG  CD2  sing Y N 460 
PHE CD1 CE1  sing Y N 461 
PHE CD1 HD1  sing N N 462 
PHE CD2 CE2  doub Y N 463 
PHE CD2 HD2  sing N N 464 
PHE CE1 CZ   doub Y N 465 
PHE CE1 HE1  sing N N 466 
PHE CE2 CZ   sing Y N 467 
PHE CE2 HE2  sing N N 468 
PHE CZ  HZ   sing N N 469 
PHE OXT HXT  sing N N 470 
PRO N   CA   sing N N 471 
PRO N   CD   sing N N 472 
PRO N   H    sing N N 473 
PRO CA  C    sing N N 474 
PRO CA  CB   sing N N 475 
PRO CA  HA   sing N N 476 
PRO C   O    doub N N 477 
PRO C   OXT  sing N N 478 
PRO CB  CG   sing N N 479 
PRO CB  HB2  sing N N 480 
PRO CB  HB3  sing N N 481 
PRO CG  CD   sing N N 482 
PRO CG  HG2  sing N N 483 
PRO CG  HG3  sing N N 484 
PRO CD  HD2  sing N N 485 
PRO CD  HD3  sing N N 486 
PRO OXT HXT  sing N N 487 
PSF O2  P    sing N N 488 
PSF O2  C2   sing N N 489 
PSF O1  P    sing N N 490 
PSF O1  CB   sing N N 491 
PSF P   O4   doub N N 492 
PSF P   O3   sing N N 493 
PSF O3  HO3  sing N N 494 
PSF C2  C3   sing N N 495 
PSF C2  H21  sing N N 496 
PSF C2  H22  sing N N 497 
PSF C3  O11  sing N N 498 
PSF C3  C4   sing N N 499 
PSF C3  H31  sing N N 500 
PSF O11 C1   sing N N 501 
PSF O12 C1   doub N N 502 
PSF C1  C13  sing N N 503 
PSF C4  O52  sing N N 504 
PSF C4  H41  sing N N 505 
PSF C4  H42  sing N N 506 
PSF C5  O51  doub N N 507 
PSF C5  O52  sing N N 508 
PSF C5  C6   sing N N 509 
PSF C6  C7   sing N N 510 
PSF C6  H61  sing N N 511 
PSF C6  H62  sing N N 512 
PSF C7  C8   sing N N 513 
PSF C7  H71  sing N N 514 
PSF C7  H72  sing N N 515 
PSF C13 C14  sing N N 516 
PSF C13 H131 sing N N 517 
PSF C13 H132 sing N N 518 
PSF C14 C15  sing N N 519 
PSF C14 H141 sing N N 520 
PSF C14 H142 sing N N 521 
PSF C15 C16  sing N N 522 
PSF C15 H151 sing N N 523 
PSF C15 H152 sing N N 524 
PSF N   CA   sing N N 525 
PSF N   H1   sing N N 526 
PSF N   H2   sing N N 527 
PSF CA  CB   sing N N 528 
PSF CA  C    sing N N 529 
PSF CA  HA   sing N N 530 
PSF CB  HB1  sing N N 531 
PSF CB  HB2  sing N N 532 
PSF C   OT1  doub N N 533 
PSF C   OT2  sing N N 534 
PSF OT2 HXT  sing N N 535 
PSF C8  C9   sing N N 536 
PSF C8  H81  sing N N 537 
PSF C8  H82  sing N N 538 
PSF C9  C10  sing N N 539 
PSF C9  H91  sing N N 540 
PSF C9  H92  sing N N 541 
PSF C10 H101 sing N N 542 
PSF C10 H102 sing N N 543 
PSF C10 H103 sing N N 544 
PSF C16 C17  sing N N 545 
PSF C16 H161 sing N N 546 
PSF C16 H162 sing N N 547 
PSF C17 H171 sing N N 548 
PSF C17 H172 sing N N 549 
PSF C17 H173 sing N N 550 
SER N   CA   sing N N 551 
SER N   H    sing N N 552 
SER N   H2   sing N N 553 
SER CA  C    sing N N 554 
SER CA  CB   sing N N 555 
SER CA  HA   sing N N 556 
SER C   O    doub N N 557 
SER C   OXT  sing N N 558 
SER CB  OG   sing N N 559 
SER CB  HB2  sing N N 560 
SER CB  HB3  sing N N 561 
SER OG  HG   sing N N 562 
SER OXT HXT  sing N N 563 
T7X O2  C2   sing N N 564 
T7X O3  C3   sing N N 565 
T7X C2  C3   sing N N 566 
T7X C2  C1   sing N N 567 
T7X O1  C1   sing N N 568 
T7X O1  P1   sing N N 569 
T7X O11 P1   doub N N 570 
T7X O6  C6   sing N N 571 
T7X C3  C4   sing N N 572 
T7X C1  C6   sing N N 573 
T7X C7  C8   sing N N 574 
T7X C7  O13  sing N N 575 
T7X P1  O13  sing N N 576 
T7X P1  O12  sing N N 577 
T7X O17 C10  doub N N 578 
T7X C6  C5   sing N N 579 
T7X C4  O4   sing N N 580 
T7X C4  C5   sing N N 581 
T7X C8  O16  sing N N 582 
T7X C8  C9   sing N N 583 
T7X O16 C10  sing N N 584 
T7X C10 C12  sing N N 585 
T7X C5  O5   sing N N 586 
T7X C9  O18  sing N N 587 
T7X C14 C13  sing N N 588 
T7X C14 C15  sing N N 589 
T7X C13 C12  sing N N 590 
T7X O18 C11  sing N N 591 
T7X C17 C16  sing N N 592 
T7X C17 C18  sing N N 593 
T7X C15 C16  doub N Z 594 
T7X C11 O19  doub N N 595 
T7X C11 C31  sing N N 596 
T7X C20 C21  sing N N 597 
T7X C20 C19  sing N N 598 
T7X C22 C21  doub N E 599 
T7X C22 C23  sing N N 600 
T7X C31 C32  sing N N 601 
T7X C23 C24  sing N N 602 
T7X C24 C25  doub N E 603 
T7X C18 C19  doub N Z 604 
T7X C25 C26  sing N N 605 
T7X C32 C33  sing N N 606 
T7X C33 C34  sing N N 607 
T7X C26 C27  sing N N 608 
T7X C35 C34  sing N N 609 
T7X C35 C36  sing N N 610 
T7X C37 C36  sing N N 611 
T7X C37 C38  sing N N 612 
T7X C41 C40  sing N N 613 
T7X C39 C38  sing N N 614 
T7X C39 C40  sing N N 615 
T7X C1  H1   sing N N 616 
T7X C2  H2   sing N N 617 
T7X O2  H3   sing N N 618 
T7X C3  H4   sing N N 619 
T7X O3  H5   sing N N 620 
T7X C4  H6   sing N N 621 
T7X O4  H7   sing N N 622 
T7X C5  H8   sing N N 623 
T7X O5  H9   sing N N 624 
T7X C6  H10  sing N N 625 
T7X O6  H11  sing N N 626 
T7X C7  H12  sing N N 627 
T7X C7  H13  sing N N 628 
T7X C8  H14  sing N N 629 
T7X C9  H15  sing N N 630 
T7X C9  H16  sing N N 631 
T7X C12 H17  sing N N 632 
T7X C12 H18  sing N N 633 
T7X O12 H19  sing N N 634 
T7X C13 H20  sing N N 635 
T7X C13 H21  sing N N 636 
T7X C14 H22  sing N N 637 
T7X C14 H23  sing N N 638 
T7X C15 H24  sing N N 639 
T7X C16 H25  sing N N 640 
T7X C17 H26  sing N N 641 
T7X C17 H27  sing N N 642 
T7X C18 H28  sing N N 643 
T7X C19 H29  sing N N 644 
T7X C20 H30  sing N N 645 
T7X C21 H32  sing N N 646 
T7X C22 H34  sing N N 647 
T7X C23 H36  sing N N 648 
T7X C24 H38  sing N N 649 
T7X C25 H40  sing N N 650 
T7X C26 H42  sing N N 651 
T7X C26 H43  sing N N 652 
T7X C27 H44  sing N N 653 
T7X C27 H45  sing N N 654 
T7X C31 H47  sing N N 655 
T7X C31 H48  sing N N 656 
T7X C32 H49  sing N N 657 
T7X C32 H50  sing N N 658 
T7X C33 H51  sing N N 659 
T7X C33 H52  sing N N 660 
T7X C34 H53  sing N N 661 
T7X C34 H54  sing N N 662 
T7X C35 H55  sing N N 663 
T7X C35 H56  sing N N 664 
T7X C36 H57  sing N N 665 
T7X C36 H58  sing N N 666 
T7X C37 H59  sing N N 667 
T7X C37 H60  sing N N 668 
T7X C38 H61  sing N N 669 
T7X C38 H62  sing N N 670 
T7X C39 H63  sing N N 671 
T7X C39 H64  sing N N 672 
T7X C40 H65  sing N N 673 
T7X C40 H66  sing N N 674 
T7X C41 H67  sing N N 675 
T7X C41 H68  sing N N 676 
T7X C27 C28  sing N N 677 
T7X C28 C29  sing N N 678 
T7X C29 C30  sing N N 679 
T7X C41 C42  sing N N 680 
T7X C42 C43  sing N N 681 
T7X C43 C44  sing N N 682 
T7X C44 C45  sing N N 683 
T7X C45 C46  sing N N 684 
T7X C20 H31  sing N N 685 
T7X C23 H33  sing N N 686 
T7X C28 H35  sing N N 687 
T7X C28 H37  sing N N 688 
T7X C29 H39  sing N N 689 
T7X C29 H41  sing N N 690 
T7X C30 H46  sing N N 691 
T7X C30 H69  sing N N 692 
T7X C30 H70  sing N N 693 
T7X C42 H71  sing N N 694 
T7X C42 H72  sing N N 695 
T7X C43 H73  sing N N 696 
T7X C43 H74  sing N N 697 
T7X C44 H75  sing N N 698 
T7X C44 H76  sing N N 699 
T7X C45 H77  sing N N 700 
T7X C45 H78  sing N N 701 
T7X C46 H79  sing N N 702 
T7X C46 H80  sing N N 703 
T7X C46 C47  sing N N 704 
T7X C47 H81  sing N N 705 
T7X C47 H82  sing N N 706 
T7X C47 H83  sing N N 707 
THR N   CA   sing N N 708 
THR N   H    sing N N 709 
THR N   H2   sing N N 710 
THR CA  C    sing N N 711 
THR CA  CB   sing N N 712 
THR CA  HA   sing N N 713 
THR C   O    doub N N 714 
THR C   OXT  sing N N 715 
THR CB  OG1  sing N N 716 
THR CB  CG2  sing N N 717 
THR CB  HB   sing N N 718 
THR OG1 HG1  sing N N 719 
THR CG2 HG21 sing N N 720 
THR CG2 HG22 sing N N 721 
THR CG2 HG23 sing N N 722 
THR OXT HXT  sing N N 723 
TRP N   CA   sing N N 724 
TRP N   H    sing N N 725 
TRP N   H2   sing N N 726 
TRP CA  C    sing N N 727 
TRP CA  CB   sing N N 728 
TRP CA  HA   sing N N 729 
TRP C   O    doub N N 730 
TRP C   OXT  sing N N 731 
TRP CB  CG   sing N N 732 
TRP CB  HB2  sing N N 733 
TRP CB  HB3  sing N N 734 
TRP CG  CD1  doub Y N 735 
TRP CG  CD2  sing Y N 736 
TRP CD1 NE1  sing Y N 737 
TRP CD1 HD1  sing N N 738 
TRP CD2 CE2  doub Y N 739 
TRP CD2 CE3  sing Y N 740 
TRP NE1 CE2  sing Y N 741 
TRP NE1 HE1  sing N N 742 
TRP CE2 CZ2  sing Y N 743 
TRP CE3 CZ3  doub Y N 744 
TRP CE3 HE3  sing N N 745 
TRP CZ2 CH2  doub Y N 746 
TRP CZ2 HZ2  sing N N 747 
TRP CZ3 CH2  sing Y N 748 
TRP CZ3 HZ3  sing N N 749 
TRP CH2 HH2  sing N N 750 
TRP OXT HXT  sing N N 751 
TYR N   CA   sing N N 752 
TYR N   H    sing N N 753 
TYR N   H2   sing N N 754 
TYR CA  C    sing N N 755 
TYR CA  CB   sing N N 756 
TYR CA  HA   sing N N 757 
TYR C   O    doub N N 758 
TYR C   OXT  sing N N 759 
TYR CB  CG   sing N N 760 
TYR CB  HB2  sing N N 761 
TYR CB  HB3  sing N N 762 
TYR CG  CD1  doub Y N 763 
TYR CG  CD2  sing Y N 764 
TYR CD1 CE1  sing Y N 765 
TYR CD1 HD1  sing N N 766 
TYR CD2 CE2  doub Y N 767 
TYR CD2 HD2  sing N N 768 
TYR CE1 CZ   doub Y N 769 
TYR CE1 HE1  sing N N 770 
TYR CE2 CZ   sing Y N 771 
TYR CE2 HE2  sing N N 772 
TYR CZ  OH   sing N N 773 
TYR OH  HH   sing N N 774 
TYR OXT HXT  sing N N 775 
VAL N   CA   sing N N 776 
VAL N   H    sing N N 777 
VAL N   H2   sing N N 778 
VAL CA  C    sing N N 779 
VAL CA  CB   sing N N 780 
VAL CA  HA   sing N N 781 
VAL C   O    doub N N 782 
VAL C   OXT  sing N N 783 
VAL CB  CG1  sing N N 784 
VAL CB  CG2  sing N N 785 
VAL CB  HB   sing N N 786 
VAL CG1 HG11 sing N N 787 
VAL CG1 HG12 sing N N 788 
VAL CG1 HG13 sing N N 789 
VAL CG2 HG21 sing N N 790 
VAL CG2 HG22 sing N N 791 
VAL CG2 HG23 sing N N 792 
VAL OXT HXT  sing N N 793 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-11-26 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           9KQI 
_em_admin.last_update        2025-04-02 
_em_admin.map_release_date   2025-04-02 
_em_admin.title              'Cryo-EM structure of PSS1 with calcium' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     NONE 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         48 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ?      ?           
'MODEL REFINEMENT'         ? 2  ? ? ? PHENIX 1.20.1_4487 
'IMAGE ACQUISITION'        ? 3  ? ? 1 ?      ?           
MASKING                    ? 4  ? ? ? ?      ?           
'CTF CORRECTION'           ? 5  1 ? ? ?      ?           
'LAYERLINE INDEXING'       ? 6  ? ? ? ?      ?           
'DIFFRACTION INDEXING'     ? 7  ? ? ? ?      ?           
'MODEL FITTING'            ? 8  ? ? ? ?      ?           
OTHER                      ? 9  ? ? ? ?      ?           
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ?      ?           
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ?      ?           
CLASSIFICATION             ? 12 1 ? ? ?      ?           
RECONSTRUCTION             ? 13 1 ? ? ?      ?           
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Other government' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           'LG-QS-202203-05; 22PJ1410300;32471016' 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9KQI 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
CA 
N  
O  
P  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . ASP A 1 14  ? 138.754 131.045 112.339 1.00 79.46  ? 14  ASP A N   1 
ATOM   2    C  CA  . ASP A 1 14  ? 138.173 131.198 113.667 1.00 81.99  ? 14  ASP A CA  1 
ATOM   3    C  C   . ASP A 1 14  ? 136.805 130.529 113.728 1.00 82.14  ? 14  ASP A C   1 
ATOM   4    O  O   . ASP A 1 14  ? 136.307 130.210 114.806 1.00 77.76  ? 14  ASP A O   1 
ATOM   5    C  CB  . ASP A 1 14  ? 138.060 132.677 114.040 1.00 82.82  ? 14  ASP A CB  1 
ATOM   6    C  CG  . ASP A 1 14  ? 138.145 132.910 115.536 1.00 82.92  ? 14  ASP A CG  1 
ATOM   7    O  OD1 . ASP A 1 14  ? 137.335 132.319 116.279 1.00 81.51  ? 14  ASP A OD1 1 
ATOM   8    O  OD2 . ASP A 1 14  ? 139.022 133.686 115.969 1.00 82.29  ? 14  ASP A OD2 1 
ATOM   9    N  N   . VAL A 1 15  ? 136.197 130.324 112.558 1.00 85.36  ? 15  VAL A N   1 
ATOM   10   C  CA  . VAL A 1 15  ? 134.950 129.567 112.498 1.00 84.67  ? 15  VAL A CA  1 
ATOM   11   C  C   . VAL A 1 15  ? 135.175 128.150 113.000 1.00 81.84  ? 15  VAL A C   1 
ATOM   12   O  O   . VAL A 1 15  ? 134.314 127.564 113.667 1.00 78.83  ? 15  VAL A O   1 
ATOM   13   C  CB  . VAL A 1 15  ? 134.382 129.576 111.068 1.00 81.76  ? 15  VAL A CB  1 
ATOM   14   C  CG1 . VAL A 1 15  ? 132.941 129.093 111.071 1.00 80.89  ? 15  VAL A CG1 1 
ATOM   15   C  CG2 . VAL A 1 15  ? 134.486 130.964 110.461 1.00 81.76  ? 15  VAL A CG2 1 
ATOM   16   N  N   . ASN A 1 16  ? 136.332 127.572 112.677 1.00 78.12  ? 16  ASN A N   1 
ATOM   17   C  CA  . ASN A 1 16  ? 136.697 126.268 113.211 1.00 75.36  ? 16  ASN A CA  1 
ATOM   18   C  C   . ASN A 1 16  ? 137.171 126.358 114.655 1.00 78.41  ? 16  ASN A C   1 
ATOM   19   O  O   . ASN A 1 16  ? 136.984 125.411 115.423 1.00 80.10  ? 16  ASN A O   1 
ATOM   20   C  CB  . ASN A 1 16  ? 137.784 125.634 112.346 1.00 77.35  ? 16  ASN A CB  1 
ATOM   21   C  CG  . ASN A 1 16  ? 137.505 125.782 110.866 1.00 81.62  ? 16  ASN A CG  1 
ATOM   22   O  OD1 . ASN A 1 16  ? 136.359 125.958 110.454 1.00 82.39  ? 16  ASN A OD1 1 
ATOM   23   N  ND2 . ASN A 1 16  ? 138.556 125.716 110.057 1.00 79.77  ? 16  ASN A ND2 1 
ATOM   24   N  N   . TYR A 1 17  ? 137.783 127.479 115.041 1.00 76.30  ? 17  TYR A N   1 
ATOM   25   C  CA  . TYR A 1 17  ? 138.351 127.588 116.382 1.00 74.52  ? 17  TYR A CA  1 
ATOM   26   C  C   . TYR A 1 17  ? 137.261 127.645 117.444 1.00 75.85  ? 17  TYR A C   1 
ATOM   27   O  O   . TYR A 1 17  ? 137.490 127.262 118.597 1.00 75.01  ? 17  TYR A O   1 
ATOM   28   C  CB  . TYR A 1 17  ? 139.255 128.818 116.470 1.00 74.47  ? 17  TYR A CB  1 
ATOM   29   C  CG  . TYR A 1 17  ? 140.606 128.644 115.812 1.00 76.98  ? 17  TYR A CG  1 
ATOM   30   C  CD1 . TYR A 1 17  ? 140.825 127.640 114.880 1.00 78.06  ? 17  TYR A CD1 1 
ATOM   31   C  CD2 . TYR A 1 17  ? 141.661 129.492 116.113 1.00 76.35  ? 17  TYR A CD2 1 
ATOM   32   C  CE1 . TYR A 1 17  ? 142.054 127.480 114.273 1.00 75.07  ? 17  TYR A CE1 1 
ATOM   33   C  CE2 . TYR A 1 17  ? 142.897 129.340 115.510 1.00 76.42  ? 17  TYR A CE2 1 
ATOM   34   C  CZ  . TYR A 1 17  ? 143.087 128.331 114.592 1.00 75.18  ? 17  TYR A CZ  1 
ATOM   35   O  OH  . TYR A 1 17  ? 144.312 128.172 113.988 1.00 75.39  ? 17  TYR A OH  1 
ATOM   36   N  N   . LYS A 1 18  ? 136.076 128.134 117.082 1.00 68.72  ? 18  LYS A N   1 
ATOM   37   C  CA  . LYS A 1 18  ? 134.939 128.136 117.993 1.00 63.97  ? 18  LYS A CA  1 
ATOM   38   C  C   . LYS A 1 18  ? 134.034 126.931 117.796 1.00 58.73  ? 18  LYS A C   1 
ATOM   39   O  O   . LYS A 1 18  ? 133.307 126.556 118.720 1.00 59.91  ? 18  LYS A O   1 
ATOM   40   C  CB  . LYS A 1 18  ? 134.124 129.419 117.818 1.00 64.23  ? 18  LYS A CB  1 
ATOM   41   C  CG  . LYS A 1 18  ? 133.535 129.964 119.104 1.00 65.61  ? 18  LYS A CG  1 
ATOM   42   C  CD  . LYS A 1 18  ? 133.126 131.418 118.938 1.00 66.66  ? 18  LYS A CD  1 
ATOM   43   C  CE  . LYS A 1 18  ? 133.009 132.119 120.278 1.00 63.29  ? 18  LYS A CE  1 
ATOM   44   N  NZ  . LYS A 1 18  ? 131.873 131.598 121.081 1.00 61.20  ? 18  LYS A NZ  1 
ATOM   45   N  N   . MET A 1 19  ? 134.044 126.332 116.604 1.00 64.18  ? 19  MET A N   1 
ATOM   46   C  CA  . MET A 1 19  ? 133.301 125.098 116.383 1.00 65.01  ? 19  MET A CA  1 
ATOM   47   C  C   . MET A 1 19  ? 134.032 123.898 116.970 1.00 61.09  ? 19  MET A C   1 
ATOM   48   O  O   . MET A 1 19  ? 133.395 122.964 117.466 1.00 67.28  ? 19  MET A O   1 
ATOM   49   C  CB  . MET A 1 19  ? 133.052 124.891 114.890 1.00 69.70  ? 19  MET A CB  1 
ATOM   50   C  CG  . MET A 1 19  ? 132.594 123.488 114.524 1.00 69.54  ? 19  MET A CG  1 
ATOM   51   S  SD  . MET A 1 19  ? 133.073 122.995 112.858 1.00 81.75  ? 19  MET A SD  1 
ATOM   52   C  CE  . MET A 1 19  ? 132.481 121.307 112.826 1.00 68.06  ? 19  MET A CE  1 
ATOM   53   N  N   . HIS A 1 20  ? 135.365 123.902 116.920 1.00 51.95  ? 20  HIS A N   1 
ATOM   54   C  CA  . HIS A 1 20  ? 136.130 122.800 117.487 1.00 52.70  ? 20  HIS A CA  1 
ATOM   55   C  C   . HIS A 1 20  ? 136.055 122.765 119.004 1.00 57.02  ? 20  HIS A C   1 
ATOM   56   O  O   . HIS A 1 20  ? 136.333 121.721 119.599 1.00 55.74  ? 20  HIS A O   1 
ATOM   57   C  CB  . HIS A 1 20  ? 137.588 122.879 117.045 1.00 55.28  ? 20  HIS A CB  1 
ATOM   58   C  CG  . HIS A 1 20  ? 137.943 121.902 115.971 1.00 59.96  ? 20  HIS A CG  1 
ATOM   59   N  ND1 . HIS A 1 20  ? 138.202 120.574 116.230 1.00 59.98  ? 20  HIS A ND1 1 
ATOM   60   C  CD2 . HIS A 1 20  ? 138.063 122.054 114.631 1.00 59.42  ? 20  HIS A CD2 1 
ATOM   61   C  CE1 . HIS A 1 20  ? 138.476 119.952 115.098 1.00 60.25  ? 20  HIS A CE1 1 
ATOM   62   N  NE2 . HIS A 1 20  ? 138.397 120.827 114.112 1.00 59.47  ? 20  HIS A NE2 1 
ATOM   63   N  N   . PHE A 1 21  ? 135.699 123.876 119.644 1.00 50.45  ? 21  PHE A N   1 
ATOM   64   C  CA  . PHE A 1 21  ? 135.490 123.849 121.084 1.00 34.51  ? 21  PHE A CA  1 
ATOM   65   C  C   . PHE A 1 21  ? 134.188 123.148 121.442 1.00 40.92  ? 21  PHE A C   1 
ATOM   66   O  O   . PHE A 1 21  ? 134.121 122.445 122.453 1.00 54.60  ? 21  PHE A O   1 
ATOM   67   C  CB  . PHE A 1 21  ? 135.498 125.264 121.650 1.00 31.36  ? 21  PHE A CB  1 
ATOM   68   C  CG  . PHE A 1 21  ? 135.278 125.319 123.128 1.00 37.25  ? 21  PHE A CG  1 
ATOM   69   C  CD1 . PHE A 1 21  ? 136.167 124.709 123.992 1.00 42.21  ? 21  PHE A CD1 1 
ATOM   70   C  CD2 . PHE A 1 21  ? 134.183 125.970 123.655 1.00 45.21  ? 21  PHE A CD2 1 
ATOM   71   C  CE1 . PHE A 1 21  ? 135.971 124.754 125.349 1.00 35.11  ? 21  PHE A CE1 1 
ATOM   72   C  CE2 . PHE A 1 21  ? 133.982 126.014 125.012 1.00 48.85  ? 21  PHE A CE2 1 
ATOM   73   C  CZ  . PHE A 1 21  ? 134.879 125.407 125.859 1.00 41.37  ? 21  PHE A CZ  1 
ATOM   74   N  N   . ARG A 1 22  ? 133.148 123.316 120.632 1.00 44.26  ? 22  ARG A N   1 
ATOM   75   C  CA  . ARG A 1 22  ? 131.891 122.636 120.901 1.00 45.04  ? 22  ARG A CA  1 
ATOM   76   C  C   . ARG A 1 22  ? 131.917 121.158 120.548 1.00 49.49  ? 22  ARG A C   1 
ATOM   77   O  O   . ARG A 1 22  ? 130.956 120.455 120.858 1.00 57.31  ? 22  ARG A O   1 
ATOM   78   C  CB  . ARG A 1 22  ? 130.740 123.309 120.161 1.00 45.31  ? 22  ARG A CB  1 
ATOM   79   C  CG  . ARG A 1 22  ? 130.707 124.812 120.269 1.00 52.25  ? 22  ARG A CG  1 
ATOM   80   C  CD  . ARG A 1 22  ? 129.507 125.356 119.516 1.00 54.20  ? 22  ARG A CD  1 
ATOM   81   N  NE  . ARG A 1 22  ? 128.343 125.453 120.386 1.00 57.95  ? 22  ARG A NE  1 
ATOM   82   C  CZ  . ARG A 1 22  ? 127.464 124.475 120.563 1.00 62.84  ? 22  ARG A CZ  1 
ATOM   83   N  NH1 . ARG A 1 22  ? 127.553 123.335 119.898 1.00 61.44  ? 22  ARG A NH1 1 
ATOM   84   N  NH2 . ARG A 1 22  ? 126.471 124.642 121.430 1.00 57.51  ? 22  ARG A NH2 1 
ATOM   85   N  N   . MET A 1 23  ? 132.964 120.664 119.900 1.00 45.64  ? 23  MET A N   1 
ATOM   86   C  CA  . MET A 1 23  ? 133.154 119.224 119.838 1.00 42.96  ? 23  MET A CA  1 
ATOM   87   C  C   . MET A 1 23  ? 133.846 118.694 121.079 1.00 48.27  ? 23  MET A C   1 
ATOM   88   O  O   . MET A 1 23  ? 133.800 117.487 121.335 1.00 52.74  ? 23  MET A O   1 
ATOM   89   C  CB  . MET A 1 23  ? 133.961 118.837 118.598 1.00 45.28  ? 23  MET A CB  1 
ATOM   90   C  CG  . MET A 1 23  ? 133.312 119.230 117.286 1.00 52.55  ? 23  MET A CG  1 
ATOM   91   S  SD  . MET A 1 23  ? 134.467 119.219 115.904 1.00 64.78  ? 23  MET A SD  1 
ATOM   92   C  CE  . MET A 1 23  ? 135.764 118.170 116.554 1.00 50.48  ? 23  MET A CE  1 
ATOM   93   N  N   . ILE A 1 24  ? 134.479 119.576 121.847 1.00 38.23  ? 24  ILE A N   1 
ATOM   94   C  CA  . ILE A 1 24  ? 135.063 119.207 123.129 1.00 28.00  ? 24  ILE A CA  1 
ATOM   95   C  C   . ILE A 1 24  ? 134.071 119.454 124.251 1.00 33.53  ? 24  ILE A C   1 
ATOM   96   O  O   . ILE A 1 24  ? 133.803 118.570 125.070 1.00 50.34  ? 24  ILE A O   1 
ATOM   97   C  CB  . ILE A 1 24  ? 136.364 119.996 123.361 1.00 35.10  ? 24  ILE A CB  1 
ATOM   98   C  CG1 . ILE A 1 24  ? 137.549 119.324 122.688 1.00 33.52  ? 24  ILE A CG1 1 
ATOM   99   C  CG2 . ILE A 1 24  ? 136.648 120.147 124.834 1.00 41.42  ? 24  ILE A CG2 1 
ATOM   100  C  CD1 . ILE A 1 24  ? 138.836 120.054 122.969 1.00 37.82  ? 24  ILE A CD1 1 
ATOM   101  N  N   . ASN A 1 25  ? 133.506 120.659 124.301 1.00 21.22  ? 25  ASN A N   1 
ATOM   102  C  CA  . ASN A 1 25  ? 132.706 121.064 125.449 1.00 24.41  ? 25  ASN A CA  1 
ATOM   103  C  C   . ASN A 1 25  ? 131.304 120.468 125.397 1.00 34.51  ? 25  ASN A C   1 
ATOM   104  O  O   . ASN A 1 25  ? 130.878 119.783 126.330 1.00 36.98  ? 25  ASN A O   1 
ATOM   105  C  CB  . ASN A 1 25  ? 132.646 122.587 125.525 1.00 28.14  ? 25  ASN A CB  1 
ATOM   106  C  CG  . ASN A 1 25  ? 132.558 123.089 126.940 1.00 38.85  ? 25  ASN A CG  1 
ATOM   107  O  OD1 . ASN A 1 25  ? 132.930 122.389 127.878 1.00 41.58  ? 25  ASN A OD1 1 
ATOM   108  N  ND2 . ASN A 1 25  ? 132.062 124.308 127.107 1.00 35.16  ? 25  ASN A ND2 1 
ATOM   109  N  N   . GLU A 1 26  ? 130.564 120.720 124.321 1.00 39.10  ? 26  GLU A N   1 
ATOM   110  C  CA  . GLU A 1 26  ? 129.176 120.272 124.208 1.00 34.34  ? 26  GLU A CA  1 
ATOM   111  C  C   . GLU A 1 26  ? 129.027 119.407 122.966 1.00 39.42  ? 26  GLU A C   1 
ATOM   112  O  O   . GLU A 1 26  ? 128.583 119.880 121.920 1.00 45.97  ? 26  GLU A O   1 
ATOM   113  C  CB  . GLU A 1 26  ? 128.240 121.448 124.159 1.00 37.69  ? 26  GLU A CB  1 
ATOM   114  C  CG  . GLU A 1 26  ? 128.701 122.657 124.933 1.00 46.28  ? 26  GLU A CG  1 
ATOM   115  C  CD  . GLU A 1 26  ? 127.541 123.437 125.502 1.00 50.85  ? 26  GLU A CD  1 
ATOM   116  O  OE1 . GLU A 1 26  ? 126.512 122.811 125.829 1.00 46.01  ? 26  GLU A OE1 1 
ATOM   117  O  OE2 . GLU A 1 26  ? 127.652 124.674 125.621 1.00 55.01  ? 26  GLU A OE2 1 
ATOM   118  N  N   . GLN A 1 27  ? 129.348 118.125 123.096 1.00 38.04  ? 27  GLN A N   1 
ATOM   119  C  CA  . GLN A 1 27  ? 129.210 117.213 121.972 1.00 32.43  ? 27  GLN A CA  1 
ATOM   120  C  C   . GLN A 1 27  ? 127.736 116.952 121.695 1.00 41.10  ? 27  GLN A C   1 
ATOM   121  O  O   . GLN A 1 27  ? 126.971 116.628 122.607 1.00 44.46  ? 27  GLN A O   1 
ATOM   122  C  CB  . GLN A 1 27  ? 129.939 115.907 122.258 1.00 35.63  ? 27  GLN A CB  1 
ATOM   123  C  CG  . GLN A 1 27  ? 129.643 114.808 121.264 1.00 44.98  ? 27  GLN A CG  1 
ATOM   124  C  CD  . GLN A 1 27  ? 130.341 115.020 119.944 1.00 49.76  ? 27  GLN A CD  1 
ATOM   125  O  OE1 . GLN A 1 27  ? 131.248 115.841 119.837 1.00 56.35  ? 27  GLN A OE1 1 
ATOM   126  N  NE2 . GLN A 1 27  ? 129.916 114.287 118.924 1.00 47.37  ? 27  GLN A NE2 1 
ATOM   127  N  N   . GLN A 1 28  ? 127.340 117.088 120.434 1.00 50.86  ? 28  GLN A N   1 
ATOM   128  C  CA  . GLN A 1 28  ? 125.943 116.987 120.044 1.00 51.28  ? 28  GLN A CA  1 
ATOM   129  C  C   . GLN A 1 28  ? 125.594 115.564 119.636 1.00 53.21  ? 28  GLN A C   1 
ATOM   130  O  O   . GLN A 1 28  ? 126.435 114.815 119.136 1.00 53.66  ? 28  GLN A O   1 
ATOM   131  C  CB  . GLN A 1 28  ? 125.638 117.941 118.891 1.00 49.89  ? 28  GLN A CB  1 
ATOM   132  C  CG  . GLN A 1 28  ? 125.896 119.396 119.216 1.00 54.98  ? 28  GLN A CG  1 
ATOM   133  C  CD  . GLN A 1 28  ? 124.706 120.060 119.866 1.00 61.30  ? 28  GLN A CD  1 
ATOM   134  O  OE1 . GLN A 1 28  ? 123.667 120.246 119.235 1.00 60.51  ? 28  GLN A OE1 1 
ATOM   135  N  NE2 . GLN A 1 28  ? 124.848 120.421 121.136 1.00 56.21  ? 28  GLN A NE2 1 
ATOM   136  N  N   . VAL A 1 29  ? 124.336 115.199 119.852 1.00 49.48  ? 29  VAL A N   1 
ATOM   137  C  CA  . VAL A 1 29  ? 123.860 113.863 119.518 1.00 48.38  ? 29  VAL A CA  1 
ATOM   138  C  C   . VAL A 1 29  ? 123.631 113.776 118.017 1.00 52.85  ? 29  VAL A C   1 
ATOM   139  O  O   . VAL A 1 29  ? 122.973 114.638 117.424 1.00 52.58  ? 29  VAL A O   1 
ATOM   140  C  CB  . VAL A 1 29  ? 122.579 113.530 120.293 1.00 46.46  ? 29  VAL A CB  1 
ATOM   141  C  CG1 . VAL A 1 29  ? 122.366 112.034 120.323 1.00 45.24  ? 29  VAL A CG1 1 
ATOM   142  C  CG2 . VAL A 1 29  ? 122.657 114.088 121.695 1.00 47.31  ? 29  VAL A CG2 1 
ATOM   143  N  N   . GLU A 1 30  ? 124.171 112.731 117.402 1.00 60.60  ? 30  GLU A N   1 
ATOM   144  C  CA  . GLU A 1 30  ? 124.055 112.510 115.970 1.00 58.81  ? 30  GLU A CA  1 
ATOM   145  C  C   . GLU A 1 30  ? 123.020 111.431 115.694 1.00 60.64  ? 30  GLU A C   1 
ATOM   146  O  O   . GLU A 1 30  ? 122.933 110.441 116.426 1.00 64.21  ? 30  GLU A O   1 
ATOM   147  C  CB  . GLU A 1 30  ? 125.402 112.106 115.368 1.00 61.86  ? 30  GLU A CB  1 
ATOM   148  C  CG  . GLU A 1 30  ? 126.258 113.280 114.921 1.00 63.29  ? 30  GLU A CG  1 
ATOM   149  C  CD  . GLU A 1 30  ? 127.267 113.703 115.969 1.00 66.79  ? 30  GLU A CD  1 
ATOM   150  O  OE1 . GLU A 1 30  ? 127.429 112.974 116.969 1.00 64.86  ? 30  GLU A OE1 1 
ATOM   151  O  OE2 . GLU A 1 30  ? 127.898 114.765 115.792 1.00 62.90  ? 30  GLU A OE2 1 
ATOM   152  N  N   . ASP A 1 31  ? 122.236 111.634 114.637 1.00 64.38  ? 31  ASP A N   1 
ATOM   153  C  CA  . ASP A 1 31  ? 121.266 110.651 114.159 1.00 65.25  ? 31  ASP A CA  1 
ATOM   154  C  C   . ASP A 1 31  ? 120.256 110.293 115.250 1.00 67.50  ? 31  ASP A C   1 
ATOM   155  O  O   . ASP A 1 31  ? 120.178 109.158 115.719 1.00 66.85  ? 31  ASP A O   1 
ATOM   156  C  CB  . ASP A 1 31  ? 121.972 109.400 113.627 1.00 64.52  ? 31  ASP A CB  1 
ATOM   157  C  CG  . ASP A 1 31  ? 122.770 109.671 112.365 1.00 69.83  ? 31  ASP A CG  1 
ATOM   158  O  OD1 . ASP A 1 31  ? 122.600 110.755 111.769 1.00 68.81  ? 31  ASP A OD1 1 
ATOM   159  O  OD2 . ASP A 1 31  ? 123.568 108.798 111.968 1.00 70.94  ? 31  ASP A OD2 1 
ATOM   160  N  N   . ILE A 1 32  ? 119.481 111.294 115.650 1.00 65.48  ? 32  ILE A N   1 
ATOM   161  C  CA  . ILE A 1 32  ? 118.401 111.095 116.607 1.00 60.85  ? 32  ILE A CA  1 
ATOM   162  C  C   . ILE A 1 32  ? 117.191 110.533 115.876 1.00 63.72  ? 32  ILE A C   1 
ATOM   163  O  O   . ILE A 1 32  ? 116.740 111.099 114.875 1.00 69.70  ? 32  ILE A O   1 
ATOM   164  C  CB  . ILE A 1 32  ? 118.050 112.413 117.312 1.00 57.49  ? 32  ILE A CB  1 
ATOM   165  C  CG1 . ILE A 1 32  ? 119.266 112.975 118.041 1.00 61.97  ? 32  ILE A CG1 1 
ATOM   166  C  CG2 . ILE A 1 32  ? 116.903 112.209 118.277 1.00 59.03  ? 32  ILE A CG2 1 
ATOM   167  C  CD1 . ILE A 1 32  ? 119.095 114.409 118.465 1.00 63.81  ? 32  ILE A CD1 1 
ATOM   168  N  N   . THR A 1 33  ? 116.664 109.416 116.370 1.00 58.76  ? 33  THR A N   1 
ATOM   169  C  CA  . THR A 1 33  ? 115.451 108.822 115.826 1.00 61.03  ? 33  THR A CA  1 
ATOM   170  C  C   . THR A 1 33  ? 114.274 108.929 116.782 1.00 61.93  ? 33  THR A C   1 
ATOM   171  O  O   . THR A 1 33  ? 113.185 109.345 116.379 1.00 65.57  ? 33  THR A O   1 
ATOM   172  C  CB  . THR A 1 33  ? 115.689 107.352 115.463 1.00 61.37  ? 33  THR A CB  1 
ATOM   173  O  OG1 . THR A 1 33  ? 116.050 106.620 116.637 1.00 63.83  ? 33  THR A OG1 1 
ATOM   174  C  CG2 . THR A 1 33  ? 116.801 107.237 114.441 1.00 61.49  ? 33  THR A CG2 1 
ATOM   175  N  N   . ILE A 1 34  ? 114.467 108.560 118.045 1.00 53.91  ? 34  ILE A N   1 
ATOM   176  C  CA  . ILE A 1 34  ? 113.470 108.780 119.084 1.00 50.56  ? 34  ILE A CA  1 
ATOM   177  C  C   . ILE A 1 34  ? 113.722 110.182 119.629 1.00 58.28  ? 34  ILE A C   1 
ATOM   178  O  O   . ILE A 1 34  ? 114.669 110.410 120.381 1.00 63.03  ? 34  ILE A O   1 
ATOM   179  C  CB  . ILE A 1 34  ? 113.543 107.716 120.178 1.00 50.01  ? 34  ILE A CB  1 
ATOM   180  C  CG1 . ILE A 1 34  ? 113.034 106.379 119.647 1.00 55.56  ? 34  ILE A CG1 1 
ATOM   181  C  CG2 . ILE A 1 34  ? 112.728 108.128 121.380 1.00 51.69  ? 34  ILE A CG2 1 
ATOM   182  C  CD1 . ILE A 1 34  ? 113.028 105.289 120.680 1.00 57.90  ? 34  ILE A CD1 1 
ATOM   183  N  N   . ASP A 1 35  ? 112.882 111.130 119.227 1.00 58.46  ? 35  ASP A N   1 
ATOM   184  C  CA  . ASP A 1 35  ? 113.055 112.527 119.593 1.00 50.97  ? 35  ASP A CA  1 
ATOM   185  C  C   . ASP A 1 35  ? 112.376 112.885 120.904 1.00 54.39  ? 35  ASP A C   1 
ATOM   186  O  O   . ASP A 1 35  ? 112.484 114.032 121.344 1.00 57.28  ? 35  ASP A O   1 
ATOM   187  C  CB  . ASP A 1 35  ? 112.531 113.434 118.477 1.00 54.50  ? 35  ASP A CB  1 
ATOM   188  C  CG  . ASP A 1 35  ? 113.499 114.551 118.129 1.00 63.95  ? 35  ASP A CG  1 
ATOM   189  O  OD1 . ASP A 1 35  ? 113.939 115.270 119.050 1.00 59.87  ? 35  ASP A OD1 1 
ATOM   190  O  OD2 . ASP A 1 35  ? 113.822 114.711 116.933 1.00 66.98  ? 35  ASP A OD2 1 
ATOM   191  N  N   . PHE A 1 36  ? 111.673 111.943 121.533 1.00 54.96  ? 36  PHE A N   1 
ATOM   192  C  CA  . PHE A 1 36  ? 111.119 112.211 122.855 1.00 55.52  ? 36  PHE A CA  1 
ATOM   193  C  C   . PHE A 1 36  ? 112.220 112.359 123.896 1.00 56.15  ? 36  PHE A C   1 
ATOM   194  O  O   . PHE A 1 36  ? 112.046 113.077 124.886 1.00 55.33  ? 36  PHE A O   1 
ATOM   195  C  CB  . PHE A 1 36  ? 110.148 111.100 123.259 1.00 48.58  ? 36  PHE A CB  1 
ATOM   196  C  CG  . PHE A 1 36  ? 110.017 110.925 124.743 1.00 51.34  ? 36  PHE A CG  1 
ATOM   197  C  CD1 . PHE A 1 36  ? 109.207 111.768 125.480 1.00 57.93  ? 36  PHE A CD1 1 
ATOM   198  C  CD2 . PHE A 1 36  ? 110.701 109.921 125.402 1.00 54.96  ? 36  PHE A CD2 1 
ATOM   199  C  CE1 . PHE A 1 36  ? 109.085 111.617 126.847 1.00 59.16  ? 36  PHE A CE1 1 
ATOM   200  C  CE2 . PHE A 1 36  ? 110.584 109.766 126.767 1.00 55.64  ? 36  PHE A CE2 1 
ATOM   201  C  CZ  . PHE A 1 36  ? 109.774 110.615 127.491 1.00 55.15  ? 36  PHE A CZ  1 
ATOM   202  N  N   . PHE A 1 37  ? 113.356 111.701 123.686 1.00 51.35  ? 37  PHE A N   1 
ATOM   203  C  CA  . PHE A 1 37  ? 114.456 111.710 124.638 1.00 45.87  ? 37  PHE A CA  1 
ATOM   204  C  C   . PHE A 1 37  ? 115.368 112.915 124.486 1.00 45.74  ? 37  PHE A C   1 
ATOM   205  O  O   . PHE A 1 37  ? 116.310 113.054 125.271 1.00 49.99  ? 37  PHE A O   1 
ATOM   206  C  CB  . PHE A 1 37  ? 115.285 110.433 124.490 1.00 47.18  ? 37  PHE A CB  1 
ATOM   207  C  CG  . PHE A 1 37  ? 114.729 109.257 125.232 1.00 49.33  ? 37  PHE A CG  1 
ATOM   208  C  CD1 . PHE A 1 37  ? 114.841 109.174 126.603 1.00 46.67  ? 37  PHE A CD1 1 
ATOM   209  C  CD2 . PHE A 1 37  ? 114.098 108.233 124.556 1.00 47.32  ? 37  PHE A CD2 1 
ATOM   210  C  CE1 . PHE A 1 37  ? 114.332 108.095 127.285 1.00 46.00  ? 37  PHE A CE1 1 
ATOM   211  C  CE2 . PHE A 1 37  ? 113.589 107.152 125.234 1.00 46.83  ? 37  PHE A CE2 1 
ATOM   212  C  CZ  . PHE A 1 37  ? 113.707 107.083 126.600 1.00 45.97  ? 37  PHE A CZ  1 
ATOM   213  N  N   . TYR A 1 38  ? 115.125 113.784 123.500 1.00 49.01  ? 38  TYR A N   1 
ATOM   214  C  CA  . TYR A 1 38  ? 116.034 114.894 123.242 1.00 49.56  ? 38  TYR A CA  1 
ATOM   215  C  C   . TYR A 1 38  ? 115.301 116.207 122.985 1.00 49.92  ? 38  TYR A C   1 
ATOM   216  O  O   . TYR A 1 38  ? 115.886 117.124 122.400 1.00 54.19  ? 38  TYR A O   1 
ATOM   217  C  CB  . TYR A 1 38  ? 116.946 114.578 122.053 1.00 45.74  ? 38  TYR A CB  1 
ATOM   218  C  CG  . TYR A 1 38  ? 117.891 113.425 122.295 1.00 46.18  ? 38  TYR A CG  1 
ATOM   219  C  CD1 . TYR A 1 38  ? 119.020 113.585 123.079 1.00 51.03  ? 38  TYR A CD1 1 
ATOM   220  C  CD2 . TYR A 1 38  ? 117.652 112.177 121.743 1.00 47.57  ? 38  TYR A CD2 1 
ATOM   221  C  CE1 . TYR A 1 38  ? 119.884 112.536 123.305 1.00 54.08  ? 38  TYR A CE1 1 
ATOM   222  C  CE2 . TYR A 1 38  ? 118.511 111.122 121.964 1.00 49.21  ? 38  TYR A CE2 1 
ATOM   223  C  CZ  . TYR A 1 38  ? 119.627 111.309 122.746 1.00 51.10  ? 38  TYR A CZ  1 
ATOM   224  O  OH  . TYR A 1 38  ? 120.493 110.268 122.975 1.00 46.29  ? 38  TYR A OH  1 
ATOM   225  N  N   . ARG A 1 39  ? 114.041 116.323 123.400 1.00 48.90  ? 39  ARG A N   1 
ATOM   226  C  CA  . ARG A 1 39  ? 113.287 117.559 123.258 1.00 45.53  ? 39  ARG A CA  1 
ATOM   227  C  C   . ARG A 1 39  ? 113.097 118.193 124.624 1.00 53.22  ? 39  ARG A C   1 
ATOM   228  O  O   . ARG A 1 39  ? 112.488 117.568 125.505 1.00 58.30  ? 39  ARG A O   1 
ATOM   229  C  CB  . ARG A 1 39  ? 111.937 117.301 122.599 1.00 49.40  ? 39  ARG A CB  1 
ATOM   230  C  CG  . ARG A 1 39  ? 111.861 117.766 121.158 1.00 53.08  ? 39  ARG A CG  1 
ATOM   231  C  CD  . ARG A 1 39  ? 110.673 117.156 120.446 1.00 53.47  ? 39  ARG A CD  1 
ATOM   232  N  NE  . ARG A 1 39  ? 110.870 117.124 119.003 1.00 59.15  ? 39  ARG A NE  1 
ATOM   233  C  CZ  . ARG A 1 39  ? 110.114 116.435 118.159 1.00 57.82  ? 39  ARG A CZ  1 
ATOM   234  N  NH1 . ARG A 1 39  ? 109.089 115.713 118.582 1.00 58.59  ? 39  ARG A NH1 1 
ATOM   235  N  NH2 . ARG A 1 39  ? 110.395 116.469 116.860 1.00 53.07  ? 39  ARG A NH2 1 
ATOM   236  N  N   . PRO A 1 40  ? 113.591 119.407 124.850 1.00 44.55  ? 40  PRO A N   1 
ATOM   237  C  CA  . PRO A 1 40  ? 113.506 120.004 126.184 1.00 39.89  ? 40  PRO A CA  1 
ATOM   238  C  C   . PRO A 1 40  ? 112.071 120.270 126.599 1.00 48.12  ? 40  PRO A C   1 
ATOM   239  O  O   . PRO A 1 40  ? 111.188 120.487 125.768 1.00 53.03  ? 40  PRO A O   1 
ATOM   240  C  CB  . PRO A 1 40  ? 114.285 121.312 126.030 1.00 41.64  ? 40  PRO A CB  1 
ATOM   241  C  CG  . PRO A 1 40  ? 114.160 121.635 124.597 1.00 42.99  ? 40  PRO A CG  1 
ATOM   242  C  CD  . PRO A 1 40  ? 114.206 120.326 123.882 1.00 44.10  ? 40  PRO A CD  1 
ATOM   243  N  N   . HIS A 1 41  ? 111.845 120.231 127.907 1.00 42.65  ? 41  HIS A N   1 
ATOM   244  C  CA  . HIS A 1 41  ? 110.556 120.568 128.502 1.00 38.30  ? 41  HIS A CA  1 
ATOM   245  C  C   . HIS A 1 41  ? 110.780 121.450 129.725 1.00 39.15  ? 41  HIS A C   1 
ATOM   246  O  O   . HIS A 1 41  ? 110.272 121.189 130.814 1.00 41.81  ? 41  HIS A O   1 
ATOM   247  C  CB  . HIS A 1 41  ? 109.768 119.309 128.846 1.00 39.99  ? 41  HIS A CB  1 
ATOM   248  C  CG  . HIS A 1 41  ? 109.351 118.520 127.648 1.00 41.73  ? 41  HIS A CG  1 
ATOM   249  N  ND1 . HIS A 1 41  ? 108.706 119.088 126.572 1.00 42.34  ? 41  HIS A ND1 1 
ATOM   250  C  CD2 . HIS A 1 41  ? 109.491 117.207 127.351 1.00 45.18  ? 41  HIS A CD2 1 
ATOM   251  C  CE1 . HIS A 1 41  ? 108.465 118.160 125.665 1.00 43.83  ? 41  HIS A CE1 1 
ATOM   252  N  NE2 . HIS A 1 41  ? 108.931 117.009 126.113 1.00 48.36  ? 41  HIS A NE2 1 
ATOM   253  N  N   . THR A 1 42  ? 111.570 122.509 129.544 1.00 34.85  ? 42  THR A N   1 
ATOM   254  C  CA  . THR A 1 42  ? 112.035 123.308 130.671 1.00 32.12  ? 42  THR A CA  1 
ATOM   255  C  C   . THR A 1 42  ? 110.892 123.947 131.448 1.00 34.41  ? 42  THR A C   1 
ATOM   256  O  O   . THR A 1 42  ? 111.038 124.203 132.645 1.00 45.85  ? 42  THR A O   1 
ATOM   257  C  CB  . THR A 1 42  ? 112.998 124.384 130.181 1.00 33.53  ? 42  THR A CB  1 
ATOM   258  O  OG1 . THR A 1 42  ? 112.348 125.192 129.198 1.00 35.55  ? 42  THR A OG1 1 
ATOM   259  C  CG2 . THR A 1 42  ? 114.212 123.746 129.559 1.00 34.12  ? 42  THR A CG2 1 
ATOM   260  N  N   . ILE A 1 43  ? 109.763 124.234 130.800 1.00 35.50  ? 43  ILE A N   1 
ATOM   261  C  CA  . ILE A 1 43  ? 108.624 124.778 131.536 1.00 32.31  ? 43  ILE A CA  1 
ATOM   262  C  C   . ILE A 1 43  ? 107.986 123.703 132.410 1.00 37.41  ? 43  ILE A C   1 
ATOM   263  O  O   . ILE A 1 43  ? 107.538 123.978 133.528 1.00 42.61  ? 43  ILE A O   1 
ATOM   264  C  CB  . ILE A 1 43  ? 107.610 125.413 130.571 1.00 35.97  ? 43  ILE A CB  1 
ATOM   265  C  CG1 . ILE A 1 43  ? 108.233 126.616 129.872 1.00 35.91  ? 43  ILE A CG1 1 
ATOM   266  C  CG2 . ILE A 1 43  ? 106.366 125.837 131.313 1.00 37.64  ? 43  ILE A CG2 1 
ATOM   267  C  CD1 . ILE A 1 43  ? 107.323 127.275 128.879 1.00 34.01  ? 43  ILE A CD1 1 
ATOM   268  N  N   . THR A 1 44  ? 107.934 122.464 131.922 1.00 40.29  ? 44  THR A N   1 
ATOM   269  C  CA  . THR A 1 44  ? 107.486 121.368 132.774 1.00 38.75  ? 44  THR A CA  1 
ATOM   270  C  C   . THR A 1 44  ? 108.456 121.137 133.924 1.00 42.87  ? 44  THR A C   1 
ATOM   271  O  O   . THR A 1 44  ? 108.039 120.804 135.037 1.00 48.14  ? 44  THR A O   1 
ATOM   272  C  CB  . THR A 1 44  ? 107.314 120.091 131.959 1.00 39.41  ? 44  THR A CB  1 
ATOM   273  O  OG1 . THR A 1 44  ? 106.555 120.378 130.781 1.00 46.78  ? 44  THR A OG1 1 
ATOM   274  C  CG2 . THR A 1 44  ? 106.579 119.049 132.770 1.00 41.02  ? 44  THR A CG2 1 
ATOM   275  N  N   . LEU A 1 45  ? 109.755 121.310 133.677 1.00 39.66  ? 45  LEU A N   1 
ATOM   276  C  CA  . LEU A 1 45  ? 110.728 121.240 134.761 1.00 41.07  ? 45  LEU A CA  1 
ATOM   277  C  C   . LEU A 1 45  ? 110.496 122.348 135.779 1.00 39.44  ? 45  LEU A C   1 
ATOM   278  O  O   . LEU A 1 45  ? 110.596 122.122 136.989 1.00 45.02  ? 45  LEU A O   1 
ATOM   279  C  CB  . LEU A 1 45  ? 112.142 121.318 134.194 1.00 39.46  ? 45  LEU A CB  1 
ATOM   280  C  CG  . LEU A 1 45  ? 113.243 120.701 135.043 1.00 37.84  ? 45  LEU A CG  1 
ATOM   281  C  CD1 . LEU A 1 45  ? 112.930 119.253 135.309 1.00 42.58  ? 45  LEU A CD1 1 
ATOM   282  C  CD2 . LEU A 1 45  ? 114.573 120.838 134.342 1.00 37.07  ? 45  LEU A CD2 1 
ATOM   283  N  N   . LEU A 1 46  ? 110.187 123.554 135.305 1.00 29.80  ? 46  LEU A N   1 
ATOM   284  C  CA  . LEU A 1 46  ? 109.863 124.658 136.201 1.00 30.39  ? 46  LEU A CA  1 
ATOM   285  C  C   . LEU A 1 46  ? 108.649 124.331 137.060 1.00 35.91  ? 46  LEU A C   1 
ATOM   286  O  O   . LEU A 1 46  ? 108.674 124.513 138.284 1.00 48.54  ? 46  LEU A O   1 
ATOM   287  C  CB  . LEU A 1 46  ? 109.629 125.921 135.374 1.00 32.31  ? 46  LEU A CB  1 
ATOM   288  C  CG  . LEU A 1 46  ? 109.033 127.194 135.963 1.00 26.92  ? 46  LEU A CG  1 
ATOM   289  C  CD1 . LEU A 1 46  ? 109.704 127.555 137.244 1.00 30.46  ? 46  LEU A CD1 1 
ATOM   290  C  CD2 . LEU A 1 46  ? 109.185 128.318 134.965 1.00 29.39  ? 46  LEU A CD2 1 
ATOM   291  N  N   . SER A 1 47  ? 107.586 123.826 136.438 1.00 36.14  ? 47  SER A N   1 
ATOM   292  C  CA  . SER A 1 47  ? 106.391 123.464 137.190 1.00 36.34  ? 47  SER A CA  1 
ATOM   293  C  C   . SER A 1 47  ? 106.685 122.362 138.201 1.00 39.38  ? 47  SER A C   1 
ATOM   294  O  O   . SER A 1 47  ? 106.195 122.406 139.335 1.00 44.30  ? 47  SER A O   1 
ATOM   295  C  CB  . SER A 1 47  ? 105.284 123.034 136.233 1.00 38.49  ? 47  SER A CB  1 
ATOM   296  O  OG  . SER A 1 47  ? 104.290 122.295 136.915 1.00 45.76  ? 47  SER A OG  1 
ATOM   297  N  N   . PHE A 1 48  ? 107.482 121.367 137.809 1.00 35.45  ? 48  PHE A N   1 
ATOM   298  C  CA  . PHE A 1 48  ? 107.824 120.288 138.727 1.00 37.12  ? 48  PHE A CA  1 
ATOM   299  C  C   . PHE A 1 48  ? 108.607 120.807 139.923 1.00 43.56  ? 48  PHE A C   1 
ATOM   300  O  O   . PHE A 1 48  ? 108.334 120.416 141.062 1.00 46.05  ? 48  PHE A O   1 
ATOM   301  C  CB  . PHE A 1 48  ? 108.620 119.208 137.998 1.00 39.14  ? 48  PHE A CB  1 
ATOM   302  C  CG  . PHE A 1 48  ? 109.592 118.472 138.878 1.00 48.17  ? 48  PHE A CG  1 
ATOM   303  C  CD1 . PHE A 1 48  ? 109.156 117.473 139.731 1.00 46.90  ? 48  PHE A CD1 1 
ATOM   304  C  CD2 . PHE A 1 48  ? 110.943 118.776 138.848 1.00 45.76  ? 48  PHE A CD2 1 
ATOM   305  C  CE1 . PHE A 1 48  ? 110.047 116.795 140.539 1.00 43.03  ? 48  PHE A CE1 1 
ATOM   306  C  CE2 . PHE A 1 48  ? 111.835 118.102 139.653 1.00 45.20  ? 48  PHE A CE2 1 
ATOM   307  C  CZ  . PHE A 1 48  ? 111.387 117.110 140.499 1.00 41.33  ? 48  PHE A CZ  1 
ATOM   308  N  N   . THR A 1 49  ? 109.591 121.682 139.690 1.00 40.33  ? 49  THR A N   1 
ATOM   309  C  CA  . THR A 1 49  ? 110.358 122.220 140.808 1.00 37.56  ? 49  THR A CA  1 
ATOM   310  C  C   . THR A 1 49  ? 109.469 123.024 141.743 1.00 38.62  ? 49  THR A C   1 
ATOM   311  O  O   . THR A 1 49  ? 109.568 122.894 142.969 1.00 48.35  ? 49  THR A O   1 
ATOM   312  C  CB  . THR A 1 49  ? 111.519 123.085 140.315 1.00 32.72  ? 49  THR A CB  1 
ATOM   313  O  OG1 . THR A 1 49  ? 111.013 124.212 139.598 1.00 40.19  ? 49  THR A OG1 1 
ATOM   314  C  CG2 . THR A 1 49  ? 112.439 122.291 139.419 1.00 38.90  ? 49  THR A CG2 1 
ATOM   315  N  N   . ILE A 1 50  ? 108.578 123.848 141.186 1.00 35.81  ? 50  ILE A N   1 
ATOM   316  C  CA  . ILE A 1 50  ? 107.728 124.669 142.040 1.00 35.75  ? 50  ILE A CA  1 
ATOM   317  C  C   . ILE A 1 50  ? 106.789 123.800 142.866 1.00 43.26  ? 50  ILE A C   1 
ATOM   318  O  O   . ILE A 1 50  ? 106.604 124.038 144.063 1.00 46.92  ? 50  ILE A O   1 
ATOM   319  C  CB  . ILE A 1 50  ? 106.959 125.711 141.212 1.00 39.92  ? 50  ILE A CB  1 
ATOM   320  C  CG1 . ILE A 1 50  ? 107.935 126.542 140.387 1.00 41.26  ? 50  ILE A CG1 1 
ATOM   321  C  CG2 . ILE A 1 50  ? 106.143 126.601 142.120 1.00 37.79  ? 50  ILE A CG2 1 
ATOM   322  C  CD1 . ILE A 1 50  ? 108.817 127.418 141.207 1.00 43.63  ? 50  ILE A CD1 1 
ATOM   323  N  N   . VAL A 1 51  ? 106.191 122.774 142.258 1.00 43.36  ? 51  VAL A N   1 
ATOM   324  C  CA  . VAL A 1 51  ? 105.257 121.936 143.007 1.00 42.93  ? 51  VAL A CA  1 
ATOM   325  C  C   . VAL A 1 51  ? 105.990 121.092 144.046 1.00 47.54  ? 51  VAL A C   1 
ATOM   326  O  O   . VAL A 1 51  ? 105.499 120.901 145.166 1.00 52.07  ? 51  VAL A O   1 
ATOM   327  C  CB  . VAL A 1 51  ? 104.424 121.069 142.050 1.00 37.85  ? 51  VAL A CB  1 
ATOM   328  C  CG1 . VAL A 1 51  ? 103.474 120.191 142.834 1.00 37.74  ? 51  VAL A CG1 1 
ATOM   329  C  CG2 . VAL A 1 51  ? 103.649 121.951 141.099 1.00 41.41  ? 51  VAL A CG2 1 
ATOM   330  N  N   . SER A 1 52  ? 107.174 120.575 143.704 1.00 41.87  ? 52  SER A N   1 
ATOM   331  C  CA  . SER A 1 52  ? 107.952 119.807 144.669 1.00 40.30  ? 52  SER A CA  1 
ATOM   332  C  C   . SER A 1 52  ? 108.326 120.660 145.872 1.00 48.04  ? 52  SER A C   1 
ATOM   333  O  O   . SER A 1 52  ? 108.187 120.230 147.024 1.00 52.51  ? 52  SER A O   1 
ATOM   334  C  CB  . SER A 1 52  ? 109.210 119.257 144.003 1.00 40.45  ? 52  SER A CB  1 
ATOM   335  O  OG  . SER A 1 52  ? 108.924 118.789 142.702 1.00 48.28  ? 52  SER A OG  1 
ATOM   336  N  N   . LEU A 1 53  ? 108.796 121.882 145.624 1.00 39.74  ? 53  LEU A N   1 
ATOM   337  C  CA  . LEU A 1 53  ? 109.182 122.739 146.733 1.00 33.96  ? 53  LEU A CA  1 
ATOM   338  C  C   . LEU A 1 53  ? 107.969 123.217 147.517 1.00 39.26  ? 53  LEU A C   1 
ATOM   339  O  O   . LEU A 1 53  ? 108.065 123.412 148.730 1.00 48.80  ? 53  LEU A O   1 
ATOM   340  C  CB  . LEU A 1 53  ? 110.012 123.912 146.223 1.00 38.90  ? 53  LEU A CB  1 
ATOM   341  C  CG  . LEU A 1 53  ? 111.415 123.478 145.797 1.00 42.30  ? 53  LEU A CG  1 
ATOM   342  C  CD1 . LEU A 1 53  ? 112.044 124.490 144.873 1.00 42.18  ? 53  LEU A CD1 1 
ATOM   343  C  CD2 . LEU A 1 53  ? 112.292 123.244 147.009 1.00 41.10  ? 53  LEU A CD2 1 
ATOM   344  N  N   . MET A 1 54  ? 106.818 123.380 146.864 1.00 46.25  ? 54  MET A N   1 
ATOM   345  C  CA  . MET A 1 54  ? 105.596 123.691 147.598 1.00 49.35  ? 54  MET A CA  1 
ATOM   346  C  C   . MET A 1 54  ? 105.232 122.562 148.551 1.00 49.38  ? 54  MET A C   1 
ATOM   347  O  O   . MET A 1 54  ? 104.906 122.799 149.720 1.00 53.67  ? 54  MET A O   1 
ATOM   348  C  CB  . MET A 1 54  ? 104.450 123.956 146.623 1.00 45.58  ? 54  MET A CB  1 
ATOM   349  C  CG  . MET A 1 54  ? 104.047 125.409 146.522 1.00 48.80  ? 54  MET A CG  1 
ATOM   350  S  SD  . MET A 1 54  ? 102.967 125.726 145.121 1.00 69.81  ? 54  MET A SD  1 
ATOM   351  C  CE  . MET A 1 54  ? 102.280 127.312 145.589 1.00 57.11  ? 54  MET A CE  1 
ATOM   352  N  N   . TYR A 1 55  ? 105.284 121.321 148.065 1.00 46.93  ? 55  TYR A N   1 
ATOM   353  C  CA  . TYR A 1 55  ? 104.974 120.186 148.925 1.00 50.48  ? 55  TYR A CA  1 
ATOM   354  C  C   . TYR A 1 55  ? 105.948 120.099 150.093 1.00 55.90  ? 55  TYR A C   1 
ATOM   355  O  O   . TYR A 1 55  ? 105.536 119.896 151.241 1.00 55.83  ? 55  TYR A O   1 
ATOM   356  C  CB  . TYR A 1 55  ? 104.991 118.891 148.118 1.00 49.12  ? 55  TYR A CB  1 
ATOM   357  C  CG  . TYR A 1 55  ? 104.808 117.656 148.966 1.00 56.80  ? 55  TYR A CG  1 
ATOM   358  C  CD1 . TYR A 1 55  ? 103.560 117.309 149.462 1.00 56.32  ? 55  TYR A CD1 1 
ATOM   359  C  CD2 . TYR A 1 55  ? 105.885 116.839 149.278 1.00 55.28  ? 55  TYR A CD2 1 
ATOM   360  C  CE1 . TYR A 1 55  ? 103.390 116.185 150.238 1.00 57.35  ? 55  TYR A CE1 1 
ATOM   361  C  CE2 . TYR A 1 55  ? 105.725 115.714 150.056 1.00 56.70  ? 55  TYR A CE2 1 
ATOM   362  C  CZ  . TYR A 1 55  ? 104.476 115.392 150.533 1.00 61.34  ? 55  TYR A CZ  1 
ATOM   363  O  OH  . TYR A 1 55  ? 104.313 114.269 151.310 1.00 61.71  ? 55  TYR A OH  1 
ATOM   364  N  N   . PHE A 1 56  ? 107.244 120.272 149.826 1.00 54.83  ? 56  PHE A N   1 
ATOM   365  C  CA  . PHE A 1 56  ? 108.239 120.157 150.886 1.00 52.36  ? 56  PHE A CA  1 
ATOM   366  C  C   . PHE A 1 56  ? 108.254 121.354 151.828 1.00 53.76  ? 56  PHE A C   1 
ATOM   367  O  O   . PHE A 1 56  ? 108.782 121.240 152.937 1.00 54.37  ? 56  PHE A O   1 
ATOM   368  C  CB  . PHE A 1 56  ? 109.630 119.962 150.286 1.00 53.48  ? 56  PHE A CB  1 
ATOM   369  C  CG  . PHE A 1 56  ? 109.846 118.600 149.704 1.00 54.44  ? 56  PHE A CG  1 
ATOM   370  C  CD1 . PHE A 1 56  ? 109.529 117.468 150.429 1.00 54.70  ? 56  PHE A CD1 1 
ATOM   371  C  CD2 . PHE A 1 56  ? 110.367 118.450 148.434 1.00 51.94  ? 56  PHE A CD2 1 
ATOM   372  C  CE1 . PHE A 1 56  ? 109.720 116.216 149.899 1.00 55.82  ? 56  PHE A CE1 1 
ATOM   373  C  CE2 . PHE A 1 56  ? 110.564 117.200 147.900 1.00 53.42  ? 56  PHE A CE2 1 
ATOM   374  C  CZ  . PHE A 1 56  ? 110.240 116.080 148.634 1.00 55.11  ? 56  PHE A CZ  1 
ATOM   375  N  N   . ALA A 1 57  ? 107.703 122.494 151.419 1.00 45.34  ? 57  ALA A N   1 
ATOM   376  C  CA  . ALA A 1 57  ? 107.630 123.649 152.298 1.00 41.31  ? 57  ALA A CA  1 
ATOM   377  C  C   . ALA A 1 57  ? 106.354 123.687 153.117 1.00 46.07  ? 57  ALA A C   1 
ATOM   378  O  O   . ALA A 1 57  ? 106.357 124.252 154.215 1.00 54.11  ? 57  ALA A O   1 
ATOM   379  C  CB  . ALA A 1 57  ? 107.743 124.944 151.490 1.00 39.24  ? 57  ALA A CB  1 
ATOM   380  N  N   . PHE A 1 58  ? 105.267 123.099 152.621 1.00 46.79  ? 58  PHE A N   1 
ATOM   381  C  CA  . PHE A 1 58  ? 104.006 123.121 153.341 1.00 48.74  ? 58  PHE A CA  1 
ATOM   382  C  C   . PHE A 1 58  ? 103.667 121.806 154.026 1.00 48.79  ? 58  PHE A C   1 
ATOM   383  O  O   . PHE A 1 58  ? 102.682 121.757 154.767 1.00 54.32  ? 58  PHE A O   1 
ATOM   384  C  CB  . PHE A 1 58  ? 102.866 123.509 152.390 1.00 49.11  ? 58  PHE A CB  1 
ATOM   385  C  CG  . PHE A 1 58  ? 103.047 124.857 151.756 1.00 48.65  ? 58  PHE A CG  1 
ATOM   386  C  CD1 . PHE A 1 58  ? 103.390 125.953 152.523 1.00 45.03  ? 58  PHE A CD1 1 
ATOM   387  C  CD2 . PHE A 1 58  ? 102.883 125.027 150.396 1.00 49.29  ? 58  PHE A CD2 1 
ATOM   388  C  CE1 . PHE A 1 58  ? 103.563 127.188 151.945 1.00 45.86  ? 58  PHE A CE1 1 
ATOM   389  C  CE2 . PHE A 1 58  ? 103.056 126.262 149.815 1.00 49.80  ? 58  PHE A CE2 1 
ATOM   390  C  CZ  . PHE A 1 58  ? 103.396 127.342 150.590 1.00 51.76  ? 58  PHE A CZ  1 
ATOM   391  N  N   . THR A 1 59  ? 104.449 120.751 153.815 1.00 50.78  ? 59  THR A N   1 
ATOM   392  C  CA  . THR A 1 59  ? 104.158 119.457 154.415 1.00 52.07  ? 59  THR A CA  1 
ATOM   393  C  C   . THR A 1 59  ? 105.245 118.951 155.350 1.00 52.17  ? 59  THR A C   1 
ATOM   394  O  O   . THR A 1 59  ? 104.929 118.273 156.329 1.00 49.57  ? 59  THR A O   1 
ATOM   395  C  CB  . THR A 1 59  ? 103.920 118.410 153.318 1.00 51.96  ? 59  THR A CB  1 
ATOM   396  O  OG1 . THR A 1 59  ? 103.000 118.934 152.354 1.00 47.52  ? 59  THR A OG1 1 
ATOM   397  C  CG2 . THR A 1 59  ? 103.333 117.142 153.908 1.00 53.60  ? 59  THR A CG2 1 
ATOM   398  N  N   . ARG A 1 60  ? 106.508 119.270 155.087 1.00 58.31  ? 60  ARG A N   1 
ATOM   399  C  CA  . ARG A 1 60  ? 107.597 118.777 155.918 1.00 53.89  ? 60  ARG A CA  1 
ATOM   400  C  C   . ARG A 1 60  ? 107.560 119.412 157.301 1.00 53.87  ? 60  ARG A C   1 
ATOM   401  O  O   . ARG A 1 60  ? 107.302 120.609 157.448 1.00 59.31  ? 60  ARG A O   1 
ATOM   402  C  CB  . ARG A 1 60  ? 108.939 119.067 155.254 1.00 52.07  ? 60  ARG A CB  1 
ATOM   403  C  CG  . ARG A 1 60  ? 109.921 117.925 155.336 1.00 57.64  ? 60  ARG A CG  1 
ATOM   404  C  CD  . ARG A 1 60  ? 111.307 118.364 154.927 1.00 57.05  ? 60  ARG A CD  1 
ATOM   405  N  NE  . ARG A 1 60  ? 111.695 119.604 155.583 1.00 56.17  ? 60  ARG A NE  1 
ATOM   406  C  CZ  . ARG A 1 60  ? 112.469 119.668 156.655 1.00 52.83  ? 60  ARG A CZ  1 
ATOM   407  N  NH1 . ARG A 1 60  ? 112.936 118.575 157.234 1.00 51.28  ? 60  ARG A NH1 1 
ATOM   408  N  NH2 . ARG A 1 60  ? 112.782 120.857 157.159 1.00 53.45  ? 60  ARG A NH2 1 
ATOM   409  N  N   . ASP A 1 61  ? 107.832 118.602 158.320 1.00 57.21  ? 61  ASP A N   1 
ATOM   410  C  CA  . ASP A 1 61  ? 107.919 119.085 159.691 1.00 58.90  ? 61  ASP A CA  1 
ATOM   411  C  C   . ASP A 1 61  ? 109.336 119.581 159.951 1.00 64.91  ? 61  ASP A C   1 
ATOM   412  O  O   . ASP A 1 61  ? 110.295 118.807 159.866 1.00 66.55  ? 61  ASP A O   1 
ATOM   413  C  CB  . ASP A 1 61  ? 107.543 117.988 160.683 1.00 57.53  ? 61  ASP A CB  1 
ATOM   414  C  CG  . ASP A 1 61  ? 107.587 118.466 162.120 1.00 61.17  ? 61  ASP A CG  1 
ATOM   415  O  OD1 . ASP A 1 61  ? 106.784 119.352 162.475 1.00 64.31  ? 61  ASP A OD1 1 
ATOM   416  O  OD2 . ASP A 1 61  ? 108.425 117.959 162.894 1.00 61.50  ? 61  ASP A OD2 1 
ATOM   417  N  N   . ASP A 1 62  ? 109.461 120.864 160.279 1.00 59.95  ? 62  ASP A N   1 
ATOM   418  C  CA  . ASP A 1 62  ? 110.748 121.529 160.446 1.00 54.64  ? 62  ASP A CA  1 
ATOM   419  C  C   . ASP A 1 62  ? 111.018 121.879 161.906 1.00 57.83  ? 62  ASP A C   1 
ATOM   420  O  O   . ASP A 1 62  ? 111.511 122.963 162.220 1.00 54.69  ? 62  ASP A O   1 
ATOM   421  C  CB  . ASP A 1 62  ? 110.819 122.779 159.577 1.00 54.33  ? 62  ASP A CB  1 
ATOM   422  C  CG  . ASP A 1 62  ? 109.631 123.692 159.775 1.00 62.56  ? 62  ASP A CG  1 
ATOM   423  O  OD1 . ASP A 1 62  ? 108.701 123.305 160.509 1.00 64.59  ? 62  ASP A OD1 1 
ATOM   424  O  OD2 . ASP A 1 62  ? 109.626 124.799 159.198 1.00 64.68  ? 62  ASP A OD2 1 
ATOM   425  N  N   . SER A 1 63  ? 110.692 120.964 162.813 1.00 63.92  ? 63  SER A N   1 
ATOM   426  C  CA  . SER A 1 63  ? 110.837 121.190 164.243 1.00 63.11  ? 63  SER A CA  1 
ATOM   427  C  C   . SER A 1 63  ? 112.206 120.796 164.782 1.00 62.54  ? 63  SER A C   1 
ATOM   428  O  O   . SER A 1 63  ? 112.456 120.977 165.977 1.00 64.13  ? 63  SER A O   1 
ATOM   429  C  CB  . SER A 1 63  ? 109.753 120.424 165.003 1.00 67.21  ? 63  SER A CB  1 
ATOM   430  O  OG  . SER A 1 63  ? 109.739 119.059 164.621 1.00 67.95  ? 63  SER A OG  1 
ATOM   431  N  N   . VAL A 1 64  ? 113.090 120.260 163.945 1.00 60.08  ? 64  VAL A N   1 
ATOM   432  C  CA  . VAL A 1 64  ? 114.432 119.860 164.349 1.00 60.55  ? 64  VAL A CA  1 
ATOM   433  C  C   . VAL A 1 64  ? 115.425 120.560 163.433 1.00 62.19  ? 64  VAL A C   1 
ATOM   434  O  O   . VAL A 1 64  ? 115.326 120.424 162.213 1.00 67.02  ? 64  VAL A O   1 
ATOM   435  C  CB  . VAL A 1 64  ? 114.633 118.335 164.293 1.00 61.58  ? 64  VAL A CB  1 
ATOM   436  C  CG1 . VAL A 1 64  ? 114.103 117.690 165.556 1.00 61.64  ? 64  VAL A CG1 1 
ATOM   437  C  CG2 . VAL A 1 64  ? 113.925 117.757 163.085 1.00 61.08  ? 64  VAL A CG2 1 
ATOM   438  N  N   . PRO A 1 65  ? 116.388 121.315 163.966 1.00 52.97  ? 65  PRO A N   1 
ATOM   439  C  CA  . PRO A 1 65  ? 117.279 122.087 163.085 1.00 54.52  ? 65  PRO A CA  1 
ATOM   440  C  C   . PRO A 1 65  ? 118.284 121.243 162.316 1.00 58.60  ? 65  PRO A C   1 
ATOM   441  O  O   . PRO A 1 65  ? 118.604 121.583 161.169 1.00 62.15  ? 65  PRO A O   1 
ATOM   442  C  CB  . PRO A 1 65  ? 117.980 123.047 164.057 1.00 54.15  ? 65  PRO A CB  1 
ATOM   443  C  CG  . PRO A 1 65  ? 117.106 123.072 165.274 1.00 55.52  ? 65  PRO A CG  1 
ATOM   444  C  CD  . PRO A 1 65  ? 116.545 121.697 165.376 1.00 57.00  ? 65  PRO A CD  1 
ATOM   445  N  N   . GLU A 1 66  ? 118.802 120.165 162.906 1.00 61.87  ? 66  GLU A N   1 
ATOM   446  C  CA  . GLU A 1 66  ? 119.806 119.357 162.220 1.00 60.75  ? 66  GLU A CA  1 
ATOM   447  C  C   . GLU A 1 66  ? 119.232 118.727 160.956 1.00 61.94  ? 66  GLU A C   1 
ATOM   448  O  O   . GLU A 1 66  ? 119.865 118.743 159.891 1.00 62.93  ? 66  GLU A O   1 
ATOM   449  C  CB  . GLU A 1 66  ? 120.337 118.278 163.164 1.00 62.25  ? 66  GLU A CB  1 
ATOM   450  C  CG  . GLU A 1 66  ? 121.140 118.809 164.344 1.00 63.85  ? 66  GLU A CG  1 
ATOM   451  C  CD  . GLU A 1 66  ? 120.261 119.273 165.493 1.00 67.38  ? 66  GLU A CD  1 
ATOM   452  O  OE1 . GLU A 1 66  ? 119.212 118.640 165.733 1.00 66.98  ? 66  GLU A OE1 1 
ATOM   453  O  OE2 . GLU A 1 66  ? 120.621 120.265 166.159 1.00 66.18  ? 66  GLU A OE2 1 
ATOM   454  N  N   . ASP A 1 67  ? 118.024 118.172 161.057 1.00 55.55  ? 67  ASP A N   1 
ATOM   455  C  CA  . ASP A 1 67  ? 117.378 117.589 159.889 1.00 54.98  ? 67  ASP A CA  1 
ATOM   456  C  C   . ASP A 1 67  ? 117.030 118.648 158.858 1.00 57.62  ? 67  ASP A C   1 
ATOM   457  O  O   . ASP A 1 67  ? 117.105 118.383 157.653 1.00 63.78  ? 67  ASP A O   1 
ATOM   458  C  CB  . ASP A 1 67  ? 116.131 116.819 160.314 1.00 57.23  ? 67  ASP A CB  1 
ATOM   459  C  CG  . ASP A 1 67  ? 116.460 115.621 161.180 1.00 64.64  ? 67  ASP A CG  1 
ATOM   460  O  OD1 . ASP A 1 67  ? 116.999 114.630 160.644 1.00 65.91  ? 67  ASP A OD1 1 
ATOM   461  O  OD2 . ASP A 1 67  ? 116.194 115.671 162.398 1.00 64.43  ? 67  ASP A OD2 1 
ATOM   462  N  N   . ASN A 1 68  ? 116.653 119.848 159.305 1.00 48.46  ? 68  ASN A N   1 
ATOM   463  C  CA  . ASN A 1 68  ? 116.397 120.934 158.367 1.00 41.08  ? 68  ASN A CA  1 
ATOM   464  C  C   . ASN A 1 68  ? 117.645 121.277 157.571 1.00 46.35  ? 68  ASN A C   1 
ATOM   465  O  O   . ASN A 1 68  ? 117.585 121.431 156.348 1.00 53.71  ? 68  ASN A O   1 
ATOM   466  C  CB  . ASN A 1 68  ? 115.888 122.164 159.109 1.00 38.87  ? 68  ASN A CB  1 
ATOM   467  C  CG  . ASN A 1 68  ? 114.575 121.918 159.794 1.00 46.43  ? 68  ASN A CG  1 
ATOM   468  O  OD1 . ASN A 1 68  ? 113.669 121.323 159.220 1.00 55.63  ? 68  ASN A OD1 1 
ATOM   469  N  ND2 . ASN A 1 68  ? 114.456 122.380 161.027 1.00 45.86  ? 68  ASN A ND2 1 
ATOM   470  N  N   . ILE A 1 69  ? 118.790 121.382 158.245 1.00 42.96  ? 69  ILE A N   1 
ATOM   471  C  CA  . ILE A 1 69  ? 120.027 121.709 157.541 1.00 43.90  ? 69  ILE A CA  1 
ATOM   472  C  C   . ILE A 1 69  ? 120.407 120.591 156.579 1.00 46.36  ? 69  ILE A C   1 
ATOM   473  O  O   . ILE A 1 69  ? 120.823 120.847 155.441 1.00 51.37  ? 69  ILE A O   1 
ATOM   474  C  CB  . ILE A 1 69  ? 121.153 122.008 158.544 1.00 46.46  ? 69  ILE A CB  1 
ATOM   475  C  CG1 . ILE A 1 69  ? 120.787 123.225 159.389 1.00 47.10  ? 69  ILE A CG1 1 
ATOM   476  C  CG2 . ILE A 1 69  ? 122.457 122.256 157.820 1.00 46.09  ? 69  ILE A CG2 1 
ATOM   477  C  CD1 . ILE A 1 69  ? 121.839 123.604 160.389 1.00 47.25  ? 69  ILE A CD1 1 
ATOM   478  N  N   . TRP A 1 70  ? 120.269 119.336 157.013 1.00 44.30  ? 70  TRP A N   1 
ATOM   479  C  CA  . TRP A 1 70  ? 120.626 118.220 156.140 1.00 42.28  ? 70  TRP A CA  1 
ATOM   480  C  C   . TRP A 1 70  ? 119.755 118.193 154.889 1.00 39.51  ? 70  TRP A C   1 
ATOM   481  O  O   . TRP A 1 70  ? 120.260 118.065 153.766 1.00 46.13  ? 70  TRP A O   1 
ATOM   482  C  CB  . TRP A 1 70  ? 120.515 116.901 156.902 1.00 40.93  ? 70  TRP A CB  1 
ATOM   483  C  CG  . TRP A 1 70  ? 120.955 115.709 156.110 1.00 43.83  ? 70  TRP A CG  1 
ATOM   484  C  CD1 . TRP A 1 70  ? 120.264 114.552 155.928 1.00 42.97  ? 70  TRP A CD1 1 
ATOM   485  C  CD2 . TRP A 1 70  ? 122.188 115.556 155.393 1.00 47.75  ? 70  TRP A CD2 1 
ATOM   486  N  NE1 . TRP A 1 70  ? 120.984 113.688 155.143 1.00 42.87  ? 70  TRP A NE1 1 
ATOM   487  C  CE2 . TRP A 1 70  ? 122.171 114.281 154.804 1.00 43.99  ? 70  TRP A CE2 1 
ATOM   488  C  CE3 . TRP A 1 70  ? 123.305 116.373 155.194 1.00 44.06  ? 70  TRP A CE3 1 
ATOM   489  C  CZ2 . TRP A 1 70  ? 123.221 113.806 154.030 1.00 45.65  ? 70  TRP A CZ2 1 
ATOM   490  C  CZ3 . TRP A 1 70  ? 124.344 115.898 154.427 1.00 41.24  ? 70  TRP A CZ3 1 
ATOM   491  C  CH2 . TRP A 1 70  ? 124.296 114.628 153.855 1.00 44.29  ? 70  TRP A CH2 1 
ATOM   492  N  N   . ARG A 1 71  ? 118.439 118.323 155.061 1.00 38.76  ? 71  ARG A N   1 
ATOM   493  C  CA  . ARG A 1 71  ? 117.550 118.289 153.908 1.00 37.94  ? 71  ARG A CA  1 
ATOM   494  C  C   . ARG A 1 71  ? 117.733 119.512 153.023 1.00 44.48  ? 71  ARG A C   1 
ATOM   495  O  O   . ARG A 1 71  ? 117.580 119.413 151.802 1.00 49.39  ? 71  ARG A O   1 
ATOM   496  C  CB  . ARG A 1 71  ? 116.100 118.160 154.362 1.00 37.68  ? 71  ARG A CB  1 
ATOM   497  C  CG  . ARG A 1 71  ? 115.734 116.755 154.792 1.00 40.50  ? 71  ARG A CG  1 
ATOM   498  C  CD  . ARG A 1 71  ? 114.692 116.149 153.865 1.00 46.20  ? 71  ARG A CD  1 
ATOM   499  N  NE  . ARG A 1 71  ? 115.035 116.320 152.457 1.00 52.41  ? 71  ARG A NE  1 
ATOM   500  C  CZ  . ARG A 1 71  ? 114.288 115.899 151.445 1.00 51.76  ? 71  ARG A CZ  1 
ATOM   501  N  NH1 . ARG A 1 71  ? 113.147 115.262 151.647 1.00 48.90  ? 71  ARG A NH1 1 
ATOM   502  N  NH2 . ARG A 1 71  ? 114.696 116.124 150.200 1.00 41.52  ? 71  ARG A NH2 1 
ATOM   503  N  N   . GLY A 1 72  ? 118.075 120.663 153.602 1.00 36.06  ? 72  GLY A N   1 
ATOM   504  C  CA  . GLY A 1 72  ? 118.380 121.820 152.782 1.00 35.93  ? 72  GLY A CA  1 
ATOM   505  C  C   . GLY A 1 72  ? 119.610 121.613 151.922 1.00 39.95  ? 72  GLY A C   1 
ATOM   506  O  O   . GLY A 1 72  ? 119.625 121.983 150.749 1.00 41.61  ? 72  GLY A O   1 
ATOM   507  N  N   . ILE A 1 73  ? 120.658 121.015 152.494 1.00 39.99  ? 73  ILE A N   1 
ATOM   508  C  CA  . ILE A 1 73  ? 121.858 120.708 151.716 1.00 33.22  ? 73  ILE A CA  1 
ATOM   509  C  C   . ILE A 1 73  ? 121.527 119.741 150.586 1.00 34.83  ? 73  ILE A C   1 
ATOM   510  O  O   . ILE A 1 73  ? 121.952 119.925 149.437 1.00 42.56  ? 73  ILE A O   1 
ATOM   511  C  CB  . ILE A 1 73  ? 122.957 120.143 152.631 1.00 31.22  ? 73  ILE A CB  1 
ATOM   512  C  CG1 . ILE A 1 73  ? 123.408 121.192 153.640 1.00 41.62  ? 73  ILE A CG1 1 
ATOM   513  C  CG2 . ILE A 1 73  ? 124.134 119.664 151.814 1.00 31.28  ? 73  ILE A CG2 1 
ATOM   514  C  CD1 . ILE A 1 73  ? 124.321 120.645 154.696 1.00 41.00  ? 73  ILE A CD1 1 
ATOM   515  N  N   . LEU A 1 74  ? 120.763 118.691 150.899 1.00 34.03  ? 74  LEU A N   1 
ATOM   516  C  CA  . LEU A 1 74  ? 120.396 117.714 149.876 1.00 28.95  ? 74  LEU A CA  1 
ATOM   517  C  C   . LEU A 1 74  ? 119.586 118.359 148.759 1.00 34.24  ? 74  LEU A C   1 
ATOM   518  O  O   . LEU A 1 74  ? 119.818 118.090 147.574 1.00 40.70  ? 74  LEU A O   1 
ATOM   519  C  CB  . LEU A 1 74  ? 119.610 116.568 150.507 1.00 29.19  ? 74  LEU A CB  1 
ATOM   520  C  CG  . LEU A 1 74  ? 120.368 115.645 151.453 1.00 27.73  ? 74  LEU A CG  1 
ATOM   521  C  CD1 . LEU A 1 74  ? 119.549 114.405 151.732 1.00 31.74  ? 74  LEU A CD1 1 
ATOM   522  C  CD2 . LEU A 1 74  ? 121.709 115.277 150.865 1.00 37.09  ? 74  LEU A CD2 1 
ATOM   523  N  N   . SER A 1 75  ? 118.632 119.217 149.119 1.00 34.88  ? 75  SER A N   1 
ATOM   524  C  CA  . SER A 1 75  ? 117.802 119.877 148.121 1.00 34.18  ? 75  SER A CA  1 
ATOM   525  C  C   . SER A 1 75  ? 118.613 120.847 147.275 1.00 31.81  ? 75  SER A C   1 
ATOM   526  O  O   . SER A 1 75  ? 118.378 120.968 146.069 1.00 33.81  ? 75  SER A O   1 
ATOM   527  C  CB  . SER A 1 75  ? 116.651 120.600 148.806 1.00 34.05  ? 75  SER A CB  1 
ATOM   528  O  OG  . SER A 1 75  ? 115.700 121.036 147.859 1.00 51.65  ? 75  SER A OG  1 
ATOM   529  N  N   . VAL A 1 76  ? 119.564 121.553 147.886 1.00 29.73  ? 76  VAL A N   1 
ATOM   530  C  CA  . VAL A 1 76  ? 120.426 122.446 147.122 1.00 23.41  ? 76  VAL A CA  1 
ATOM   531  C  C   . VAL A 1 76  ? 121.243 121.657 146.109 1.00 32.95  ? 76  VAL A C   1 
ATOM   532  O  O   . VAL A 1 76  ? 121.384 122.069 144.954 1.00 39.23  ? 76  VAL A O   1 
ATOM   533  C  CB  . VAL A 1 76  ? 121.326 123.261 148.065 1.00 26.37  ? 76  VAL A CB  1 
ATOM   534  C  CG1 . VAL A 1 76  ? 122.488 123.842 147.304 1.00 27.72  ? 76  VAL A CG1 1 
ATOM   535  C  CG2 . VAL A 1 76  ? 120.533 124.362 148.729 1.00 31.13  ? 76  VAL A CG2 1 
ATOM   536  N  N   . ILE A 1 77  ? 121.782 120.506 146.514 1.00 34.81  ? 77  ILE A N   1 
ATOM   537  C  CA  . ILE A 1 77  ? 122.546 119.680 145.578 1.00 27.56  ? 77  ILE A CA  1 
ATOM   538  C  C   . ILE A 1 77  ? 121.655 119.204 144.434 1.00 25.08  ? 77  ILE A C   1 
ATOM   539  O  O   . ILE A 1 77  ? 122.036 119.261 143.257 1.00 31.66  ? 77  ILE A O   1 
ATOM   540  C  CB  . ILE A 1 77  ? 123.197 118.498 146.315 1.00 25.90  ? 77  ILE A CB  1 
ATOM   541  C  CG1 . ILE A 1 77  ? 124.229 118.999 147.321 1.00 27.62  ? 77  ILE A CG1 1 
ATOM   542  C  CG2 . ILE A 1 77  ? 123.843 117.554 145.329 1.00 32.35  ? 77  ILE A CG2 1 
ATOM   543  C  CD1 . ILE A 1 77  ? 124.761 117.921 148.220 1.00 28.60  ? 77  ILE A CD1 1 
ATOM   544  N  N   . PHE A 1 78  ? 120.451 118.732 144.762 1.00 29.64  ? 78  PHE A N   1 
ATOM   545  C  CA  . PHE A 1 78  ? 119.550 118.213 143.736 1.00 24.58  ? 78  PHE A CA  1 
ATOM   546  C  C   . PHE A 1 78  ? 119.159 119.299 142.738 1.00 35.44  ? 78  PHE A C   1 
ATOM   547  O  O   . PHE A 1 78  ? 119.175 119.084 141.519 1.00 42.62  ? 78  PHE A O   1 
ATOM   548  C  CB  . PHE A 1 78  ? 118.313 117.613 144.400 1.00 25.01  ? 78  PHE A CB  1 
ATOM   549  C  CG  . PHE A 1 78  ? 117.266 117.154 143.434 1.00 30.20  ? 78  PHE A CG  1 
ATOM   550  C  CD1 . PHE A 1 78  ? 117.405 115.961 142.758 1.00 38.82  ? 78  PHE A CD1 1 
ATOM   551  C  CD2 . PHE A 1 78  ? 116.135 117.910 143.210 1.00 33.06  ? 78  PHE A CD2 1 
ATOM   552  C  CE1 . PHE A 1 78  ? 116.442 115.536 141.875 1.00 37.22  ? 78  PHE A CE1 1 
ATOM   553  C  CE2 . PHE A 1 78  ? 115.170 117.489 142.329 1.00 28.36  ? 78  PHE A CE2 1 
ATOM   554  C  CZ  . PHE A 1 78  ? 115.324 116.302 141.659 1.00 30.24  ? 78  PHE A CZ  1 
ATOM   555  N  N   . PHE A 1 79  ? 118.815 120.484 143.232 1.00 34.30  ? 79  PHE A N   1 
ATOM   556  C  CA  . PHE A 1 79  ? 118.395 121.538 142.324 1.00 21.10  ? 79  PHE A CA  1 
ATOM   557  C  C   . PHE A 1 79  ? 119.564 122.183 141.596 1.00 24.48  ? 79  PHE A C   1 
ATOM   558  O  O   . PHE A 1 79  ? 119.368 122.728 140.508 1.00 36.70  ? 79  PHE A O   1 
ATOM   559  C  CB  . PHE A 1 79  ? 117.570 122.574 143.080 1.00 28.95  ? 79  PHE A CB  1 
ATOM   560  C  CG  . PHE A 1 79  ? 116.164 122.127 143.340 1.00 34.71  ? 79  PHE A CG  1 
ATOM   561  C  CD1 . PHE A 1 79  ? 115.225 122.137 142.330 1.00 34.91  ? 79  PHE A CD1 1 
ATOM   562  C  CD2 . PHE A 1 79  ? 115.792 121.654 144.582 1.00 33.39  ? 79  PHE A CD2 1 
ATOM   563  C  CE1 . PHE A 1 79  ? 113.941 121.707 142.563 1.00 37.16  ? 79  PHE A CE1 1 
ATOM   564  C  CE2 . PHE A 1 79  ? 114.507 121.226 144.818 1.00 30.30  ? 79  PHE A CE2 1 
ATOM   565  C  CZ  . PHE A 1 79  ? 113.581 121.252 143.807 1.00 32.55  ? 79  PHE A CZ  1 
ATOM   566  N  N   . PHE A 1 80  ? 120.782 122.092 142.130 1.00 18.14  ? 80  PHE A N   1 
ATOM   567  C  CA  . PHE A 1 80  ? 121.937 122.468 141.326 1.00 19.43  ? 80  PHE A CA  1 
ATOM   568  C  C   . PHE A 1 80  ? 122.156 121.477 140.195 1.00 27.32  ? 80  PHE A C   1 
ATOM   569  O  O   . PHE A 1 80  ? 122.586 121.860 139.106 1.00 30.52  ? 80  PHE A O   1 
ATOM   570  C  CB  . PHE A 1 80  ? 123.190 122.571 142.186 1.00 20.85  ? 80  PHE A CB  1 
ATOM   571  C  CG  . PHE A 1 80  ? 124.345 123.209 141.477 1.00 23.76  ? 80  PHE A CG  1 
ATOM   572  C  CD1 . PHE A 1 80  ? 124.276 124.522 141.059 1.00 23.79  ? 80  PHE A CD1 1 
ATOM   573  C  CD2 . PHE A 1 80  ? 125.491 122.492 141.210 1.00 21.75  ? 80  PHE A CD2 1 
ATOM   574  C  CE1 . PHE A 1 80  ? 125.331 125.109 140.404 1.00 26.69  ? 80  PHE A CE1 1 
ATOM   575  C  CE2 . PHE A 1 80  ? 126.548 123.076 140.556 1.00 22.22  ? 80  PHE A CE2 1 
ATOM   576  C  CZ  . PHE A 1 80  ? 126.467 124.386 140.154 1.00 25.26  ? 80  PHE A CZ  1 
ATOM   577  N  N   . LEU A 1 81  ? 121.870 120.196 140.431 1.00 27.43  ? 81  LEU A N   1 
ATOM   578  C  CA  . LEU A 1 81  ? 121.902 119.236 139.330 1.00 15.85  ? 81  LEU A CA  1 
ATOM   579  C  C   . LEU A 1 81  ? 120.858 119.581 138.271 1.00 23.91  ? 81  LEU A C   1 
ATOM   580  O  O   . LEU A 1 81  ? 121.120 119.479 137.065 1.00 31.58  ? 81  LEU A O   1 
ATOM   581  C  CB  . LEU A 1 81  ? 121.683 117.821 139.858 1.00 25.73  ? 81  LEU A CB  1 
ATOM   582  C  CG  . LEU A 1 81  ? 122.777 117.232 140.746 1.00 30.46  ? 81  LEU A CG  1 
ATOM   583  C  CD1 . LEU A 1 81  ? 122.696 115.722 140.733 1.00 27.44  ? 81  LEU A CD1 1 
ATOM   584  C  CD2 . LEU A 1 81  ? 124.146 117.696 140.309 1.00 21.33  ? 81  LEU A CD2 1 
ATOM   585  N  N   . ILE A 1 82  ? 119.665 119.991 138.707 1.00 29.11  ? 82  ILE A N   1 
ATOM   586  C  CA  . ILE A 1 82  ? 118.629 120.405 137.759 1.00 24.46  ? 82  ILE A CA  1 
ATOM   587  C  C   . ILE A 1 82  ? 119.066 121.638 136.971 1.00 21.89  ? 82  ILE A C   1 
ATOM   588  O  O   . ILE A 1 82  ? 118.805 121.744 135.769 1.00 30.18  ? 82  ILE A O   1 
ATOM   589  C  CB  . ILE A 1 82  ? 117.290 120.635 138.484 1.00 30.62  ? 82  ILE A CB  1 
ATOM   590  C  CG1 . ILE A 1 82  ? 116.559 119.309 138.670 1.00 30.33  ? 82  ILE A CG1 1 
ATOM   591  C  CG2 . ILE A 1 82  ? 116.416 121.610 137.726 1.00 28.31  ? 82  ILE A CG2 1 
ATOM   592  C  CD1 . ILE A 1 82  ? 115.300 119.429 139.470 1.00 27.07  ? 82  ILE A CD1 1 
ATOM   593  N  N   . ILE A 1 83  ? 119.722 122.594 137.631 1.00 21.19  ? 83  ILE A N   1 
ATOM   594  C  CA  . ILE A 1 83  ? 120.267 123.753 136.922 1.00 20.52  ? 83  ILE A CA  1 
ATOM   595  C  C   . ILE A 1 83  ? 121.340 123.326 135.928 1.00 24.09  ? 83  ILE A C   1 
ATOM   596  O  O   . ILE A 1 83  ? 121.413 123.847 134.810 1.00 32.00  ? 83  ILE A O   1 
ATOM   597  C  CB  . ILE A 1 83  ? 120.814 124.791 137.918 1.00 28.18  ? 83  ILE A CB  1 
ATOM   598  C  CG1 . ILE A 1 83  ? 119.675 125.504 138.645 1.00 28.33  ? 83  ILE A CG1 1 
ATOM   599  C  CG2 . ILE A 1 83  ? 121.712 125.785 137.210 1.00 23.54  ? 83  ILE A CG2 1 
ATOM   600  C  CD1 . ILE A 1 83  ? 118.976 126.534 137.800 1.00 26.87  ? 83  ILE A CD1 1 
ATOM   601  N  N   . SER A 1 84  ? 122.200 122.389 136.324 1.00 24.49  ? 84  SER A N   1 
ATOM   602  C  CA  . SER A 1 84  ? 123.264 121.925 135.442 1.00 21.10  ? 84  SER A CA  1 
ATOM   603  C  C   . SER A 1 84  ? 122.710 121.243 134.204 1.00 23.56  ? 84  SER A C   1 
ATOM   604  O  O   . SER A 1 84  ? 123.314 121.324 133.131 1.00 30.42  ? 84  SER A O   1 
ATOM   605  C  CB  . SER A 1 84  ? 124.187 120.976 136.198 1.00 20.16  ? 84  SER A CB  1 
ATOM   606  O  OG  . SER A 1 84  ? 123.487 119.824 136.613 1.00 33.82  ? 84  SER A OG  1 
ATOM   607  N  N   . VAL A 1 85  ? 121.577 120.554 134.332 1.00 20.10  ? 85  VAL A N   1 
ATOM   608  C  CA  . VAL A 1 85  ? 120.952 119.943 133.161 1.00 20.00  ? 85  VAL A CA  1 
ATOM   609  C  C   . VAL A 1 85  ? 120.573 121.001 132.131 1.00 27.75  ? 85  VAL A C   1 
ATOM   610  O  O   . VAL A 1 85  ? 120.638 120.753 130.922 1.00 35.07  ? 85  VAL A O   1 
ATOM   611  C  CB  . VAL A 1 85  ? 119.734 119.103 133.588 1.00 20.05  ? 85  VAL A CB  1 
ATOM   612  C  CG1 . VAL A 1 85  ? 118.901 118.721 132.396 1.00 27.04  ? 85  VAL A CG1 1 
ATOM   613  C  CG2 . VAL A 1 85  ? 120.193 117.865 134.298 1.00 23.73  ? 85  VAL A CG2 1 
ATOM   614  N  N   . LEU A 1 86  ? 120.191 122.194 132.580 1.00 25.95  ? 86  LEU A N   1 
ATOM   615  C  CA  . LEU A 1 86  ? 119.783 123.252 131.665 1.00 25.94  ? 86  LEU A CA  1 
ATOM   616  C  C   . LEU A 1 86  ? 120.929 124.139 131.205 1.00 24.61  ? 86  LEU A C   1 
ATOM   617  O  O   . LEU A 1 86  ? 120.849 124.713 130.115 1.00 36.84  ? 86  LEU A O   1 
ATOM   618  C  CB  . LEU A 1 86  ? 118.723 124.145 132.313 1.00 26.00  ? 86  LEU A CB  1 
ATOM   619  C  CG  . LEU A 1 86  ? 117.582 123.531 133.111 1.00 21.65  ? 86  LEU A CG  1 
ATOM   620  C  CD1 . LEU A 1 86  ? 116.981 124.596 133.984 1.00 26.99  ? 86  LEU A CD1 1 
ATOM   621  C  CD2 . LEU A 1 86  ? 116.538 122.967 132.190 1.00 24.45  ? 86  LEU A CD2 1 
ATOM   622  N  N   . ALA A 1 87  ? 121.990 124.281 131.999 1.00 24.97  ? 87  ALA A N   1 
ATOM   623  C  CA  . ALA A 1 87  ? 122.969 125.327 131.748 1.00 26.44  ? 87  ALA A CA  1 
ATOM   624  C  C   . ALA A 1 87  ? 124.427 124.891 131.769 1.00 29.12  ? 87  ALA A C   1 
ATOM   625  O  O   . ALA A 1 87  ? 125.302 125.760 131.748 1.00 33.23  ? 87  ALA A O   1 
ATOM   626  C  CB  . ALA A 1 87  ? 122.789 126.465 132.762 1.00 25.53  ? 87  ALA A CB  1 
ATOM   627  N  N   . PHE A 1 88  ? 124.726 123.598 131.801 1.00 20.61  ? 88  PHE A N   1 
ATOM   628  C  CA  . PHE A 1 88  ? 126.143 123.270 131.874 1.00 19.31  ? 88  PHE A CA  1 
ATOM   629  C  C   . PHE A 1 88  ? 126.568 122.394 130.698 1.00 31.78  ? 88  PHE A C   1 
ATOM   630  O  O   . PHE A 1 88  ? 125.755 121.646 130.151 1.00 41.09  ? 88  PHE A O   1 
ATOM   631  C  CB  . PHE A 1 88  ? 126.480 122.555 133.187 1.00 18.57  ? 88  PHE A CB  1 
ATOM   632  C  CG  . PHE A 1 88  ? 126.887 123.484 134.294 1.00 20.22  ? 88  PHE A CG  1 
ATOM   633  C  CD1 . PHE A 1 88  ? 127.568 124.649 134.019 1.00 25.63  ? 88  PHE A CD1 1 
ATOM   634  C  CD2 . PHE A 1 88  ? 126.600 123.186 135.607 1.00 24.04  ? 88  PHE A CD2 1 
ATOM   635  C  CE1 . PHE A 1 88  ? 127.942 125.498 135.032 1.00 30.34  ? 88  PHE A CE1 1 
ATOM   636  C  CE2 . PHE A 1 88  ? 126.971 124.032 136.620 1.00 24.42  ? 88  PHE A CE2 1 
ATOM   637  C  CZ  . PHE A 1 88  ? 127.645 125.187 136.332 1.00 24.20  ? 88  PHE A CZ  1 
ATOM   638  N  N   . PRO A 1 89  ? 127.829 122.479 130.273 1.00 20.13  ? 89  PRO A N   1 
ATOM   639  C  CA  . PRO A 1 89  ? 128.282 121.674 129.136 1.00 12.28  ? 89  PRO A CA  1 
ATOM   640  C  C   . PRO A 1 89  ? 128.410 120.203 129.490 1.00 21.33  ? 89  PRO A C   1 
ATOM   641  O  O   . PRO A 1 89  ? 128.709 119.838 130.627 1.00 33.93  ? 89  PRO A O   1 
ATOM   642  C  CB  . PRO A 1 89  ? 129.646 122.281 128.805 1.00 22.63  ? 89  PRO A CB  1 
ATOM   643  C  CG  . PRO A 1 89  ? 130.106 122.847 130.079 1.00 16.58  ? 89  PRO A CG  1 
ATOM   644  C  CD  . PRO A 1 89  ? 128.884 123.388 130.743 1.00 20.63  ? 89  PRO A CD  1 
ATOM   645  N  N   . ASN A 1 90  ? 128.212 119.352 128.483 1.00 19.60  ? 90  ASN A N   1 
ATOM   646  C  CA  . ASN A 1 90  ? 128.140 117.912 128.691 1.00 17.03  ? 90  ASN A CA  1 
ATOM   647  C  C   . ASN A 1 90  ? 129.398 117.177 128.243 1.00 25.24  ? 90  ASN A C   1 
ATOM   648  O  O   . ASN A 1 90  ? 129.359 115.958 128.061 1.00 40.10  ? 90  ASN A O   1 
ATOM   649  C  CB  . ASN A 1 90  ? 126.915 117.334 127.987 1.00 25.20  ? 90  ASN A CB  1 
ATOM   650  C  CG  . ASN A 1 90  ? 127.044 117.340 126.487 1.00 26.75  ? 90  ASN A CG  1 
ATOM   651  O  OD1 . ASN A 1 90  ? 127.558 116.398 125.894 1.00 24.42  ? 90  ASN A OD1 1 
ATOM   652  N  ND2 . ASN A 1 90  ? 126.562 118.401 125.860 1.00 29.92  ? 90  ASN A ND2 1 
ATOM   653  N  N   . GLY A 1 91  ? 130.511 117.882 128.070 1.00 26.16  ? 91  GLY A N   1 
ATOM   654  C  CA  . GLY A 1 91  ? 131.761 117.244 127.730 1.00 24.94  ? 91  GLY A CA  1 
ATOM   655  C  C   . GLY A 1 91  ? 131.761 116.729 126.309 1.00 18.14  ? 91  GLY A C   1 
ATOM   656  O  O   . GLY A 1 91  ? 130.897 117.075 125.502 1.00 24.56  ? 91  GLY A O   1 
ATOM   657  N  N   . PRO A 1 92  ? 132.741 115.893 125.968 1.00 14.90  ? 92  PRO A N   1 
ATOM   658  C  CA  . PRO A 1 92  ? 132.746 115.242 124.659 1.00 27.51  ? 92  PRO A CA  1 
ATOM   659  C  C   . PRO A 1 92  ? 131.926 113.965 124.597 1.00 34.94  ? 92  PRO A C   1 
ATOM   660  O  O   . PRO A 1 92  ? 132.014 113.239 123.604 1.00 41.58  ? 92  PRO A O   1 
ATOM   661  C  CB  . PRO A 1 92  ? 134.236 114.943 124.452 1.00 27.96  ? 92  PRO A CB  1 
ATOM   662  C  CG  . PRO A 1 92  ? 134.742 114.691 125.816 1.00 22.90  ? 92  PRO A CG  1 
ATOM   663  C  CD  . PRO A 1 92  ? 133.903 115.495 126.776 1.00 22.22  ? 92  PRO A CD  1 
ATOM   664  N  N   . PHE A 1 93  ? 131.135 113.685 125.625 1.00 27.23  ? 93  PHE A N   1 
ATOM   665  C  CA  . PHE A 1 93  ? 130.382 112.450 125.736 1.00 26.45  ? 93  PHE A CA  1 
ATOM   666  C  C   . PHE A 1 93  ? 128.901 112.732 125.545 1.00 33.81  ? 93  PHE A C   1 
ATOM   667  O  O   . PHE A 1 93  ? 128.384 113.741 126.026 1.00 36.03  ? 93  PHE A O   1 
ATOM   668  C  CB  . PHE A 1 93  ? 130.612 111.792 127.093 1.00 24.94  ? 93  PHE A CB  1 
ATOM   669  C  CG  . PHE A 1 93  ? 131.993 111.254 127.277 1.00 19.77  ? 93  PHE A CG  1 
ATOM   670  C  CD1 . PHE A 1 93  ? 132.881 111.220 126.228 1.00 29.46  ? 93  PHE A CD1 1 
ATOM   671  C  CD2 . PHE A 1 93  ? 132.398 110.775 128.497 1.00 27.97  ? 93  PHE A CD2 1 
ATOM   672  C  CE1 . PHE A 1 93  ? 134.142 110.730 126.393 1.00 26.86  ? 93  PHE A CE1 1 
ATOM   673  C  CE2 . PHE A 1 93  ? 133.659 110.280 128.664 1.00 31.26  ? 93  PHE A CE2 1 
ATOM   674  C  CZ  . PHE A 1 93  ? 134.532 110.258 127.611 1.00 30.20  ? 93  PHE A CZ  1 
ATOM   675  N  N   . THR A 1 94  ? 128.223 111.831 124.843 1.00 39.28  ? 94  THR A N   1 
ATOM   676  C  CA  . THR A 1 94  ? 126.810 112.004 124.550 1.00 31.23  ? 94  THR A CA  1 
ATOM   677  C  C   . THR A 1 94  ? 126.044 110.705 124.733 1.00 33.76  ? 94  THR A C   1 
ATOM   678  O  O   . THR A 1 94  ? 125.004 110.502 124.100 1.00 46.72  ? 94  THR A O   1 
ATOM   679  C  CB  . THR A 1 94  ? 126.602 112.531 123.136 1.00 33.56  ? 94  THR A CB  1 
ATOM   680  O  OG1 . THR A 1 94  ? 125.230 112.369 122.768 1.00 48.58  ? 94  THR A OG1 1 
ATOM   681  C  CG2 . THR A 1 94  ? 127.471 111.771 122.156 1.00 35.10  ? 94  THR A CG2 1 
ATOM   682  N  N   . ARG A 1 95  ? 126.547 109.809 125.580 1.00 29.25  ? 95  ARG A N   1 
ATOM   683  C  CA  . ARG A 1 95  ? 125.883 108.553 125.872 1.00 29.08  ? 95  ARG A CA  1 
ATOM   684  C  C   . ARG A 1 95  ? 126.042 108.229 127.350 1.00 37.44  ? 95  ARG A C   1 
ATOM   685  O  O   . ARG A 1 95  ? 127.086 108.537 127.941 1.00 42.47  ? 95  ARG A O   1 
ATOM   686  C  CB  . ARG A 1 95  ? 126.449 107.407 125.028 1.00 28.81  ? 95  ARG A CB  1 
ATOM   687  C  CG  . ARG A 1 95  ? 125.820 107.292 123.664 1.00 35.09  ? 95  ARG A CG  1 
ATOM   688  C  CD  . ARG A 1 95  ? 125.543 105.855 123.325 1.00 34.65  ? 95  ARG A CD  1 
ATOM   689  N  NE  . ARG A 1 95  ? 124.671 105.730 122.167 1.00 32.84  ? 95  ARG A NE  1 
ATOM   690  C  CZ  . ARG A 1 95  ? 124.622 104.667 121.379 1.00 38.17  ? 95  ARG A CZ  1 
ATOM   691  N  NH1 . ARG A 1 95  ? 125.386 103.612 121.598 1.00 40.47  ? 95  ARG A NH1 1 
ATOM   692  N  NH2 . ARG A 1 95  ? 123.785 104.661 120.348 1.00 45.84  ? 95  ARG A NH2 1 
ATOM   693  N  N   . PRO A 1 96  ? 125.030 107.622 127.980 1.00 35.43  ? 96  PRO A N   1 
ATOM   694  C  CA  . PRO A 1 96  ? 123.699 107.283 127.454 1.00 34.49  ? 96  PRO A CA  1 
ATOM   695  C  C   . PRO A 1 96  ? 122.860 108.520 127.152 1.00 42.60  ? 96  PRO A C   1 
ATOM   696  O  O   . PRO A 1 96  ? 122.066 108.528 126.219 1.00 46.51  ? 96  PRO A O   1 
ATOM   697  C  CB  . PRO A 1 96  ? 123.089 106.438 128.578 1.00 33.29  ? 96  PRO A CB  1 
ATOM   698  C  CG  . PRO A 1 96  ? 123.812 106.852 129.808 1.00 34.80  ? 96  PRO A CG  1 
ATOM   699  C  CD  . PRO A 1 96  ? 125.207 107.144 129.359 1.00 31.06  ? 96  PRO A CD  1 
ATOM   700  N  N   . HIS A 1 97  ? 123.020 109.584 127.929 1.00 36.63  ? 97  HIS A N   1 
ATOM   701  C  CA  . HIS A 1 97  ? 122.389 110.862 127.657 1.00 33.84  ? 97  HIS A CA  1 
ATOM   702  C  C   . HIS A 1 97  ? 123.365 111.970 128.015 1.00 32.49  ? 97  HIS A C   1 
ATOM   703  O  O   . HIS A 1 97  ? 124.147 111.825 128.960 1.00 40.67  ? 97  HIS A O   1 
ATOM   704  C  CB  . HIS A 1 97  ? 121.092 111.032 128.459 1.00 37.62  ? 97  HIS A CB  1 
ATOM   705  C  CG  . HIS A 1 97  ? 120.082 111.911 127.793 1.00 36.77  ? 97  HIS A CG  1 
ATOM   706  N  ND1 . HIS A 1 97  ? 119.972 113.255 128.068 1.00 36.05  ? 97  HIS A ND1 1 
ATOM   707  C  CD2 . HIS A 1 97  ? 119.136 111.638 126.866 1.00 34.11  ? 97  HIS A CD2 1 
ATOM   708  C  CE1 . HIS A 1 97  ? 119.005 113.774 127.337 1.00 32.31  ? 97  HIS A CE1 1 
ATOM   709  N  NE2 . HIS A 1 97  ? 118.480 112.814 126.600 1.00 32.81  ? 97  HIS A NE2 1 
ATOM   710  N  N   . PRO A 1 98  ? 123.356 113.077 127.273 1.00 25.50  ? 98  PRO A N   1 
ATOM   711  C  CA  . PRO A 1 98  ? 124.224 114.206 127.640 1.00 20.55  ? 98  PRO A CA  1 
ATOM   712  C  C   . PRO A 1 98  ? 123.914 114.793 129.004 1.00 24.23  ? 98  PRO A C   1 
ATOM   713  O  O   . PRO A 1 98  ? 124.818 115.323 129.665 1.00 37.88  ? 98  PRO A O   1 
ATOM   714  C  CB  . PRO A 1 98  ? 123.960 115.218 126.520 1.00 29.26  ? 98  PRO A CB  1 
ATOM   715  C  CG  . PRO A 1 98  ? 123.436 114.413 125.390 1.00 26.14  ? 98  PRO A CG  1 
ATOM   716  C  CD  . PRO A 1 98  ? 122.647 113.318 126.008 1.00 31.60  ? 98  PRO A CD  1 
ATOM   717  N  N   . ALA A 1 99  ? 122.658 114.720 129.447 1.00 25.87  ? 99  ALA A N   1 
ATOM   718  C  CA  . ALA A 1 99  ? 122.283 115.301 130.730 1.00 27.46  ? 99  ALA A CA  1 
ATOM   719  C  C   . ALA A 1 99  ? 122.971 114.602 131.890 1.00 29.91  ? 99  ALA A C   1 
ATOM   720  O  O   . ALA A 1 99  ? 123.282 115.240 132.901 1.00 42.45  ? 99  ALA A O   1 
ATOM   721  C  CB  . ALA A 1 99  ? 120.770 115.249 130.904 1.00 27.73  ? 99  ALA A CB  1 
ATOM   722  N  N   . LEU A 1 100 ? 123.215 113.298 131.773 1.00 23.64  ? 100 LEU A N   1 
ATOM   723  C  CA  . LEU A 1 100 ? 123.933 112.582 132.818 1.00 21.86  ? 100 LEU A CA  1 
ATOM   724  C  C   . LEU A 1 100 ? 125.384 113.017 132.930 1.00 23.29  ? 100 LEU A C   1 
ATOM   725  O  O   . LEU A 1 100 ? 126.036 112.676 133.920 1.00 37.16  ? 100 LEU A O   1 
ATOM   726  C  CB  . LEU A 1 100 ? 123.858 111.072 132.584 1.00 25.29  ? 100 LEU A CB  1 
ATOM   727  C  CG  . LEU A 1 100 ? 122.603 110.303 133.025 1.00 40.78  ? 100 LEU A CG  1 
ATOM   728  C  CD1 . LEU A 1 100 ? 121.314 111.089 132.872 1.00 41.27  ? 100 LEU A CD1 1 
ATOM   729  C  CD2 . LEU A 1 100 ? 122.492 108.995 132.277 1.00 37.79  ? 100 LEU A CD2 1 
ATOM   730  N  N   . TRP A 1 101 ? 125.903 113.749 131.947 1.00 20.92  ? 101 TRP A N   1 
ATOM   731  C  CA  . TRP A 1 101 ? 127.233 114.335 132.029 1.00 15.04  ? 101 TRP A CA  1 
ATOM   732  C  C   . TRP A 1 101 ? 127.199 115.809 132.390 1.00 24.86  ? 101 TRP A C   1 
ATOM   733  O  O   . TRP A 1 101 ? 128.140 116.306 133.018 1.00 35.96  ? 101 TRP A O   1 
ATOM   734  C  CB  . TRP A 1 101 ? 127.975 114.135 130.707 1.00 17.64  ? 101 TRP A CB  1 
ATOM   735  C  CG  . TRP A 1 101 ? 128.197 112.693 130.409 1.00 22.99  ? 101 TRP A CG  1 
ATOM   736  C  CD1 . TRP A 1 101 ? 127.512 111.928 129.520 1.00 18.25  ? 101 TRP A CD1 1 
ATOM   737  C  CD2 . TRP A 1 101 ? 129.158 111.829 131.022 1.00 29.31  ? 101 TRP A CD2 1 
ATOM   738  N  NE1 . TRP A 1 101 ? 127.988 110.645 129.534 1.00 23.97  ? 101 TRP A NE1 1 
ATOM   739  C  CE2 . TRP A 1 101 ? 129.002 110.559 130.449 1.00 29.02  ? 101 TRP A CE2 1 
ATOM   740  C  CE3 . TRP A 1 101 ? 130.140 112.010 132.000 1.00 30.65  ? 101 TRP A CE3 1 
ATOM   741  C  CZ2 . TRP A 1 101 ? 129.788 109.475 130.819 1.00 29.57  ? 101 TRP A CZ2 1 
ATOM   742  C  CZ3 . TRP A 1 101 ? 130.918 110.935 132.363 1.00 23.50  ? 101 TRP A CZ3 1 
ATOM   743  C  CH2 . TRP A 1 101 ? 130.739 109.684 131.776 1.00 24.32  ? 101 TRP A CH2 1 
ATOM   744  N  N   . ARG A 1 102 ? 126.118 116.510 132.045 1.00 22.54  ? 102 ARG A N   1 
ATOM   745  C  CA  . ARG A 1 102 ? 125.899 117.834 132.617 1.00 6.55   ? 102 ARG A CA  1 
ATOM   746  C  C   . ARG A 1 102 ? 125.779 117.756 134.133 1.00 21.58  ? 102 ARG A C   1 
ATOM   747  O  O   . ARG A 1 102 ? 126.285 118.626 134.850 1.00 34.64  ? 102 ARG A O   1 
ATOM   748  C  CB  . ARG A 1 102 ? 124.650 118.466 132.017 1.00 15.12  ? 102 ARG A CB  1 
ATOM   749  C  CG  . ARG A 1 102 ? 124.697 118.608 130.525 1.00 17.99  ? 102 ARG A CG  1 
ATOM   750  C  CD  . ARG A 1 102 ? 123.502 119.362 130.003 1.00 18.49  ? 102 ARG A CD  1 
ATOM   751  N  NE  . ARG A 1 102 ? 123.435 119.304 128.551 1.00 18.12  ? 102 ARG A NE  1 
ATOM   752  C  CZ  . ARG A 1 102 ? 122.457 118.723 127.874 1.00 30.35  ? 102 ARG A CZ  1 
ATOM   753  N  NH1 . ARG A 1 102 ? 121.432 118.160 128.489 1.00 32.55  ? 102 ARG A NH1 1 
ATOM   754  N  NH2 . ARG A 1 102 ? 122.511 118.704 126.547 1.00 30.42  ? 102 ARG A NH2 1 
ATOM   755  N  N   . MET A 1 103 ? 125.123 116.714 134.643 1.00 26.07  ? 103 MET A N   1 
ATOM   756  C  CA  . MET A 1 103 ? 125.000 116.550 136.089 1.00 17.40  ? 103 MET A CA  1 
ATOM   757  C  C   . MET A 1 103 ? 126.338 116.200 136.733 1.00 23.56  ? 103 MET A C   1 
ATOM   758  O  O   . MET A 1 103 ? 126.630 116.640 137.852 1.00 38.65  ? 103 MET A O   1 
ATOM   759  C  CB  . MET A 1 103 ? 123.948 115.492 136.400 1.00 13.85  ? 103 MET A CB  1 
ATOM   760  C  CG  . MET A 1 103 ? 122.541 115.961 136.095 1.00 24.97  ? 103 MET A CG  1 
ATOM   761  S  SD  . MET A 1 103 ? 121.291 114.671 136.086 1.00 42.56  ? 103 MET A SD  1 
ATOM   762  C  CE  . MET A 1 103 ? 122.055 113.454 137.140 1.00 30.56  ? 103 MET A CE  1 
ATOM   763  N  N   . VAL A 1 104 ? 127.172 115.421 136.044 1.00 19.84  ? 104 VAL A N   1 
ATOM   764  C  CA  . VAL A 1 104 ? 128.515 115.145 136.547 1.00 12.70  ? 104 VAL A CA  1 
ATOM   765  C  C   . VAL A 1 104 ? 129.336 116.427 136.602 1.00 18.63  ? 104 VAL A C   1 
ATOM   766  O  O   . VAL A 1 104 ? 130.084 116.661 137.558 1.00 39.83  ? 104 VAL A O   1 
ATOM   767  C  CB  . VAL A 1 104 ? 129.197 114.065 135.689 1.00 22.79  ? 104 VAL A CB  1 
ATOM   768  C  CG1 . VAL A 1 104 ? 130.684 114.051 135.933 1.00 23.73  ? 104 VAL A CG1 1 
ATOM   769  C  CG2 . VAL A 1 104 ? 128.604 112.706 135.989 1.00 21.68  ? 104 VAL A CG2 1 
ATOM   770  N  N   . PHE A 1 105 ? 129.208 117.282 135.586 1.00 25.34  ? 105 PHE A N   1 
ATOM   771  C  CA  . PHE A 1 105 ? 129.890 118.573 135.630 1.00 17.26  ? 105 PHE A CA  1 
ATOM   772  C  C   . PHE A 1 105 ? 129.366 119.442 136.769 1.00 19.04  ? 105 PHE A C   1 
ATOM   773  O  O   . PHE A 1 105 ? 130.131 120.175 137.408 1.00 28.52  ? 105 PHE A O   1 
ATOM   774  C  CB  . PHE A 1 105 ? 129.742 119.298 134.294 1.00 17.18  ? 105 PHE A CB  1 
ATOM   775  C  CG  . PHE A 1 105 ? 130.492 120.589 134.230 1.00 21.09  ? 105 PHE A CG  1 
ATOM   776  C  CD1 . PHE A 1 105 ? 131.851 120.604 134.032 1.00 23.55  ? 105 PHE A CD1 1 
ATOM   777  C  CD2 . PHE A 1 105 ? 129.839 121.790 134.387 1.00 25.37  ? 105 PHE A CD2 1 
ATOM   778  C  CE1 . PHE A 1 105 ? 132.536 121.787 133.985 1.00 23.73  ? 105 PHE A CE1 1 
ATOM   779  C  CE2 . PHE A 1 105 ? 130.529 122.974 134.340 1.00 13.96  ? 105 PHE A CE2 1 
ATOM   780  C  CZ  . PHE A 1 105 ? 131.873 122.970 134.140 1.00 13.65  ? 105 PHE A CZ  1 
ATOM   781  N  N   . GLY A 1 106 ? 128.060 119.389 137.025 1.00 20.76  ? 106 GLY A N   1 
ATOM   782  C  CA  . GLY A 1 106 ? 127.512 120.123 138.155 1.00 15.06  ? 106 GLY A CA  1 
ATOM   783  C  C   . GLY A 1 106 ? 128.091 119.662 139.478 1.00 24.91  ? 106 GLY A C   1 
ATOM   784  O  O   . GLY A 1 106 ? 128.427 120.479 140.339 1.00 39.87  ? 106 GLY A O   1 
ATOM   785  N  N   . LEU A 1 107 ? 128.227 118.347 139.654 1.00 19.61  ? 107 LEU A N   1 
ATOM   786  C  CA  . LEU A 1 107 ? 128.869 117.827 140.858 1.00 12.23  ? 107 LEU A CA  1 
ATOM   787  C  C   . LEU A 1 107 ? 130.332 118.249 140.932 1.00 19.83  ? 107 LEU A C   1 
ATOM   788  O  O   . LEU A 1 107 ? 130.854 118.520 142.020 1.00 31.60  ? 107 LEU A O   1 
ATOM   789  C  CB  . LEU A 1 107 ? 128.754 116.307 140.908 1.00 19.51  ? 107 LEU A CB  1 
ATOM   790  C  CG  . LEU A 1 107 ? 127.372 115.701 141.129 1.00 21.18  ? 107 LEU A CG  1 
ATOM   791  C  CD1 . LEU A 1 107 ? 127.472 114.196 141.126 1.00 22.76  ? 107 LEU A CD1 1 
ATOM   792  C  CD2 . LEU A 1 107 ? 126.775 116.189 142.426 1.00 27.09  ? 107 LEU A CD2 1 
ATOM   793  N  N   . SER A 1 108 ? 131.013 118.300 139.786 1.00 24.24  ? 108 SER A N   1 
ATOM   794  C  CA  . SER A 1 108 ? 132.395 118.772 139.756 1.00 16.88  ? 108 SER A CA  1 
ATOM   795  C  C   . SER A 1 108 ? 132.498 120.198 140.273 1.00 28.91  ? 108 SER A C   1 
ATOM   796  O  O   . SER A 1 108 ? 133.383 120.521 141.072 1.00 38.29  ? 108 SER A O   1 
ATOM   797  C  CB  . SER A 1 108 ? 132.946 118.694 138.337 1.00 15.21  ? 108 SER A CB  1 
ATOM   798  O  OG  . SER A 1 108 ? 132.583 117.478 137.717 1.00 41.90  ? 108 SER A OG  1 
ATOM   799  N  N   . VAL A 1 109 ? 131.601 121.071 139.814 1.00 29.11  ? 109 VAL A N   1 
ATOM   800  C  CA  . VAL A 1 109 ? 131.624 122.461 140.260 1.00 13.68  ? 109 VAL A CA  1 
ATOM   801  C  C   . VAL A 1 109 ? 131.282 122.555 141.743 1.00 18.03  ? 109 VAL A C   1 
ATOM   802  O  O   . VAL A 1 109 ? 131.875 123.353 142.483 1.00 28.16  ? 109 VAL A O   1 
ATOM   803  C  CB  . VAL A 1 109 ? 130.677 123.313 139.399 1.00 12.37  ? 109 VAL A CB  1 
ATOM   804  C  CG1 . VAL A 1 109 ? 130.503 124.686 140.004 1.00 27.94  ? 109 VAL A CG1 1 
ATOM   805  C  CG2 . VAL A 1 109 ? 131.216 123.427 137.994 1.00 20.43  ? 109 VAL A CG2 1 
ATOM   806  N  N   . LEU A 1 110 ? 130.325 121.745 142.204 1.00 26.44  ? 110 LEU A N   1 
ATOM   807  C  CA  . LEU A 1 110 ? 130.005 121.710 143.629 1.00 20.57  ? 110 LEU A CA  1 
ATOM   808  C  C   . LEU A 1 110 ? 131.235 121.364 144.456 1.00 31.10  ? 110 LEU A C   1 
ATOM   809  O  O   . LEU A 1 110 ? 131.537 122.029 145.453 1.00 35.29  ? 110 LEU A O   1 
ATOM   810  C  CB  . LEU A 1 110 ? 128.897 120.694 143.897 1.00 22.69  ? 110 LEU A CB  1 
ATOM   811  C  CG  . LEU A 1 110 ? 127.441 121.082 143.670 1.00 24.43  ? 110 LEU A CG  1 
ATOM   812  C  CD1 . LEU A 1 110 ? 126.541 119.902 143.956 1.00 26.09  ? 110 LEU A CD1 1 
ATOM   813  C  CD2 . LEU A 1 110 ? 127.060 122.249 144.536 1.00 31.79  ? 110 LEU A CD2 1 
ATOM   814  N  N   . TYR A 1 111 ? 131.963 120.323 144.050 1.00 31.34  ? 111 TYR A N   1 
ATOM   815  C  CA  . TYR A 1 111 ? 133.145 119.905 144.797 1.00 23.12  ? 111 TYR A CA  1 
ATOM   816  C  C   . TYR A 1 111 ? 134.250 120.950 144.727 1.00 26.12  ? 111 TYR A C   1 
ATOM   817  O  O   . TYR A 1 111 ? 134.961 121.176 145.712 1.00 38.39  ? 111 TYR A O   1 
ATOM   818  C  CB  . TYR A 1 111 ? 133.644 118.563 144.278 1.00 19.39  ? 111 TYR A CB  1 
ATOM   819  C  CG  . TYR A 1 111 ? 134.758 117.973 145.099 1.00 32.16  ? 111 TYR A CG  1 
ATOM   820  C  CD1 . TYR A 1 111 ? 134.668 117.907 146.477 1.00 34.29  ? 111 TYR A CD1 1 
ATOM   821  C  CD2 . TYR A 1 111 ? 135.898 117.475 144.496 1.00 40.70  ? 111 TYR A CD2 1 
ATOM   822  C  CE1 . TYR A 1 111 ? 135.683 117.365 147.229 1.00 32.87  ? 111 TYR A CE1 1 
ATOM   823  C  CE2 . TYR A 1 111 ? 136.918 116.934 145.240 1.00 31.31  ? 111 TYR A CE2 1 
ATOM   824  C  CZ  . TYR A 1 111 ? 136.806 116.880 146.604 1.00 31.65  ? 111 TYR A CZ  1 
ATOM   825  O  OH  . TYR A 1 111 ? 137.825 116.337 147.347 1.00 36.72  ? 111 TYR A OH  1 
ATOM   826  N  N   . PHE A 1 112 ? 134.416 121.595 143.573 1.00 27.07  ? 112 PHE A N   1 
ATOM   827  C  CA  . PHE A 1 112 ? 135.423 122.643 143.451 1.00 20.48  ? 112 PHE A CA  1 
ATOM   828  C  C   . PHE A 1 112 ? 135.138 123.783 144.421 1.00 22.08  ? 112 PHE A C   1 
ATOM   829  O  O   . PHE A 1 112 ? 136.039 124.259 145.121 1.00 25.38  ? 112 PHE A O   1 
ATOM   830  C  CB  . PHE A 1 112 ? 135.469 123.139 142.005 1.00 20.19  ? 112 PHE A CB  1 
ATOM   831  C  CG  . PHE A 1 112 ? 136.039 124.517 141.840 1.00 22.07  ? 112 PHE A CG  1 
ATOM   832  C  CD1 . PHE A 1 112 ? 137.319 124.814 142.264 1.00 30.89  ? 112 PHE A CD1 1 
ATOM   833  C  CD2 . PHE A 1 112 ? 135.295 125.511 141.240 1.00 25.70  ? 112 PHE A CD2 1 
ATOM   834  C  CE1 . PHE A 1 112 ? 137.837 126.082 142.104 1.00 25.78  ? 112 PHE A CE1 1 
ATOM   835  C  CE2 . PHE A 1 112 ? 135.809 126.775 141.079 1.00 27.02  ? 112 PHE A CE2 1 
ATOM   836  C  CZ  . PHE A 1 112 ? 137.082 127.060 141.511 1.00 27.36  ? 112 PHE A CZ  1 
ATOM   837  N  N   . LEU A 1 113 ? 133.879 124.215 144.500 1.00 30.06  ? 113 LEU A N   1 
ATOM   838  C  CA  . LEU A 1 113 ? 133.544 125.304 145.413 1.00 21.40  ? 113 LEU A CA  1 
ATOM   839  C  C   . LEU A 1 113 ? 133.622 124.867 146.869 1.00 30.28  ? 113 LEU A C   1 
ATOM   840  O  O   . LEU A 1 113 ? 133.985 125.671 147.735 1.00 41.58  ? 113 LEU A O   1 
ATOM   841  C  CB  . LEU A 1 113 ? 132.160 125.851 145.090 1.00 20.37  ? 113 LEU A CB  1 
ATOM   842  C  CG  . LEU A 1 113 ? 132.050 126.414 143.679 1.00 21.25  ? 113 LEU A CG  1 
ATOM   843  C  CD1 . LEU A 1 113 ? 130.612 126.688 143.349 1.00 27.95  ? 113 LEU A CD1 1 
ATOM   844  C  CD2 . LEU A 1 113 ? 132.882 127.664 143.558 1.00 25.06  ? 113 LEU A CD2 1 
ATOM   845  N  N   . PHE A 1 114 ? 133.297 123.606 147.160 1.00 32.08  ? 114 PHE A N   1 
ATOM   846  C  CA  . PHE A 1 114 ? 133.484 123.092 148.512 1.00 24.31  ? 114 PHE A CA  1 
ATOM   847  C  C   . PHE A 1 114 ? 134.949 123.146 148.917 1.00 28.80  ? 114 PHE A C   1 
ATOM   848  O  O   . PHE A 1 114 ? 135.273 123.521 150.048 1.00 38.83  ? 114 PHE A O   1 
ATOM   849  C  CB  . PHE A 1 114 ? 132.956 121.664 148.607 1.00 23.47  ? 114 PHE A CB  1 
ATOM   850  C  CG  . PHE A 1 114 ? 133.188 121.019 149.938 1.00 33.26  ? 114 PHE A CG  1 
ATOM   851  C  CD1 . PHE A 1 114 ? 132.686 121.584 151.092 1.00 33.52  ? 114 PHE A CD1 1 
ATOM   852  C  CD2 . PHE A 1 114 ? 133.905 119.844 150.034 1.00 32.58  ? 114 PHE A CD2 1 
ATOM   853  C  CE1 . PHE A 1 114 ? 132.895 120.990 152.316 1.00 27.04  ? 114 PHE A CE1 1 
ATOM   854  C  CE2 . PHE A 1 114 ? 134.116 119.248 151.257 1.00 35.96  ? 114 PHE A CE2 1 
ATOM   855  C  CZ  . PHE A 1 114 ? 133.610 119.823 152.398 1.00 29.03  ? 114 PHE A CZ  1 
ATOM   856  N  N   . LEU A 1 115 ? 135.850 122.771 148.009 1.00 32.55  ? 115 LEU A N   1 
ATOM   857  C  CA  . LEU A 1 115 ? 137.277 122.873 148.301 1.00 28.52  ? 115 LEU A CA  1 
ATOM   858  C  C   . LEU A 1 115 ? 137.701 124.323 148.481 1.00 24.86  ? 115 LEU A C   1 
ATOM   859  O  O   . LEU A 1 115 ? 138.541 124.628 149.333 1.00 31.30  ? 115 LEU A O   1 
ATOM   860  C  CB  . LEU A 1 115 ? 138.096 122.219 147.192 1.00 30.79  ? 115 LEU A CB  1 
ATOM   861  C  CG  . LEU A 1 115 ? 138.022 120.702 147.102 1.00 27.78  ? 115 LEU A CG  1 
ATOM   862  C  CD1 . LEU A 1 115 ? 138.863 120.223 145.945 1.00 27.52  ? 115 LEU A CD1 1 
ATOM   863  C  CD2 . LEU A 1 115 ? 138.478 120.081 148.403 1.00 32.15  ? 115 LEU A CD2 1 
ATOM   864  N  N   . VAL A 1 116 ? 137.150 125.229 147.670 1.00 27.30  ? 116 VAL A N   1 
ATOM   865  C  CA  . VAL A 1 116 ? 137.461 126.650 147.823 1.00 26.41  ? 116 VAL A CA  1 
ATOM   866  C  C   . VAL A 1 116 ? 137.074 127.130 149.214 1.00 31.20  ? 116 VAL A C   1 
ATOM   867  O  O   . VAL A 1 116 ? 137.803 127.899 149.849 1.00 34.78  ? 116 VAL A O   1 
ATOM   868  C  CB  . VAL A 1 116 ? 136.761 127.478 146.730 1.00 28.68  ? 116 VAL A CB  1 
ATOM   869  C  CG1 . VAL A 1 116 ? 136.890 128.948 147.024 1.00 33.02  ? 116 VAL A CG1 1 
ATOM   870  C  CG2 . VAL A 1 116 ? 137.352 127.179 145.384 1.00 30.79  ? 116 VAL A CG2 1 
ATOM   871  N  N   . PHE A 1 117 ? 135.916 126.687 149.707 1.00 40.11  ? 117 PHE A N   1 
ATOM   872  C  CA  . PHE A 1 117 ? 135.480 127.077 151.044 1.00 36.55  ? 117 PHE A CA  1 
ATOM   873  C  C   . PHE A 1 117 ? 136.425 126.552 152.119 1.00 31.22  ? 117 PHE A C   1 
ATOM   874  O  O   . PHE A 1 117 ? 136.744 127.266 153.075 1.00 34.37  ? 117 PHE A O   1 
ATOM   875  C  CB  . PHE A 1 117 ? 134.059 126.575 151.291 1.00 31.40  ? 117 PHE A CB  1 
ATOM   876  C  CG  . PHE A 1 117 ? 133.502 126.964 152.624 1.00 31.88  ? 117 PHE A CG  1 
ATOM   877  C  CD1 . PHE A 1 117 ? 133.262 128.286 152.927 1.00 35.40  ? 117 PHE A CD1 1 
ATOM   878  C  CD2 . PHE A 1 117 ? 133.221 126.006 153.574 1.00 36.29  ? 117 PHE A CD2 1 
ATOM   879  C  CE1 . PHE A 1 117 ? 132.753 128.645 154.150 1.00 35.75  ? 117 PHE A CE1 1 
ATOM   880  C  CE2 . PHE A 1 117 ? 132.710 126.361 154.798 1.00 41.88  ? 117 PHE A CE2 1 
ATOM   881  C  CZ  . PHE A 1 117 ? 132.477 127.683 155.086 1.00 36.62  ? 117 PHE A CZ  1 
ATOM   882  N  N   . LEU A 1 118 ? 136.889 125.307 151.977 1.00 31.55  ? 118 LEU A N   1 
ATOM   883  C  CA  . LEU A 1 118 ? 137.662 124.666 153.039 1.00 29.23  ? 118 LEU A CA  1 
ATOM   884  C  C   . LEU A 1 118 ? 138.996 125.354 153.285 1.00 31.78  ? 118 LEU A C   1 
ATOM   885  O  O   . LEU A 1 118 ? 139.535 125.275 154.392 1.00 38.90  ? 118 LEU A O   1 
ATOM   886  C  CB  . LEU A 1 118 ? 137.899 123.195 152.705 1.00 25.78  ? 118 LEU A CB  1 
ATOM   887  C  CG  . LEU A 1 118 ? 136.759 122.221 152.975 1.00 29.78  ? 118 LEU A CG  1 
ATOM   888  C  CD1 . LEU A 1 118 ? 137.281 120.805 152.969 1.00 32.42  ? 118 LEU A CD1 1 
ATOM   889  C  CD2 . LEU A 1 118 ? 136.096 122.537 154.293 1.00 39.68  ? 118 LEU A CD2 1 
ATOM   890  N  N   . LEU A 1 119 ? 139.556 126.012 152.271 1.00 34.49  ? 119 LEU A N   1 
ATOM   891  C  CA  . LEU A 1 119 ? 140.858 126.645 152.438 1.00 29.61  ? 119 LEU A CA  1 
ATOM   892  C  C   . LEU A 1 119 ? 140.810 127.773 153.454 1.00 41.28  ? 119 LEU A C   1 
ATOM   893  O  O   . LEU A 1 119 ? 141.832 128.105 154.061 1.00 48.19  ? 119 LEU A O   1 
ATOM   894  C  CB  . LEU A 1 119 ? 141.360 127.174 151.097 1.00 25.86  ? 119 LEU A CB  1 
ATOM   895  C  CG  . LEU A 1 119 ? 141.582 126.132 150.008 1.00 34.15  ? 119 LEU A CG  1 
ATOM   896  C  CD1 . LEU A 1 119 ? 141.643 126.793 148.659 1.00 35.92  ? 119 LEU A CD1 1 
ATOM   897  C  CD2 . LEU A 1 119 ? 142.858 125.395 150.284 1.00 36.78  ? 119 LEU A CD2 1 
ATOM   898  N  N   . PHE A 1 120 ? 139.640 128.374 153.653 1.00 46.00  ? 120 PHE A N   1 
ATOM   899  C  CA  . PHE A 1 120 ? 139.517 129.538 154.515 1.00 38.92  ? 120 PHE A CA  1 
ATOM   900  C  C   . PHE A 1 120 ? 139.156 129.193 155.950 1.00 42.24  ? 120 PHE A C   1 
ATOM   901  O  O   . PHE A 1 120 ? 139.198 130.080 156.807 1.00 49.90  ? 120 PHE A O   1 
ATOM   902  C  CB  . PHE A 1 120 ? 138.483 130.501 153.935 1.00 33.41  ? 120 PHE A CB  1 
ATOM   903  C  CG  . PHE A 1 120 ? 138.992 131.277 152.763 1.00 38.08  ? 120 PHE A CG  1 
ATOM   904  C  CD1 . PHE A 1 120 ? 138.891 130.768 151.485 1.00 37.39  ? 120 PHE A CD1 1 
ATOM   905  C  CD2 . PHE A 1 120 ? 139.591 132.506 152.942 1.00 40.44  ? 120 PHE A CD2 1 
ATOM   906  C  CE1 . PHE A 1 120 ? 139.366 131.474 150.413 1.00 40.02  ? 120 PHE A CE1 1 
ATOM   907  C  CE2 . PHE A 1 120 ? 140.069 133.214 151.873 1.00 39.20  ? 120 PHE A CE2 1 
ATOM   908  C  CZ  . PHE A 1 120 ? 139.957 132.698 150.607 1.00 41.27  ? 120 PHE A CZ  1 
ATOM   909  N  N   . LEU A 1 121 ? 138.817 127.942 156.238 1.00 34.52  ? 121 LEU A N   1 
ATOM   910  C  CA  . LEU A 1 121 ? 138.579 127.520 157.607 1.00 32.01  ? 121 LEU A CA  1 
ATOM   911  C  C   . LEU A 1 121 ? 139.908 127.187 158.277 1.00 36.40  ? 121 LEU A C   1 
ATOM   912  O  O   . LEU A 1 121 ? 140.985 127.380 157.711 1.00 42.07  ? 121 LEU A O   1 
ATOM   913  C  CB  . LEU A 1 121 ? 137.641 126.317 157.637 1.00 35.78  ? 121 LEU A CB  1 
ATOM   914  C  CG  . LEU A 1 121 ? 136.318 126.384 156.877 1.00 31.33  ? 121 LEU A CG  1 
ATOM   915  C  CD1 . LEU A 1 121 ? 135.475 125.173 157.195 1.00 34.56  ? 121 LEU A CD1 1 
ATOM   916  C  CD2 . LEU A 1 121 ? 135.565 127.651 157.201 1.00 34.75  ? 121 LEU A CD2 1 
ATOM   917  N  N   . ASN A 1 122 ? 139.838 126.688 159.504 1.00 44.40  ? 122 ASN A N   1 
ATOM   918  C  CA  . ASN A 1 122 ? 140.986 126.100 160.177 1.00 42.81  ? 122 ASN A CA  1 
ATOM   919  C  C   . ASN A 1 122 ? 140.702 124.624 160.425 1.00 51.08  ? 122 ASN A C   1 
ATOM   920  O  O   . ASN A 1 122 ? 139.635 124.112 160.088 1.00 57.64  ? 122 ASN A O   1 
ATOM   921  C  CB  . ASN A 1 122 ? 141.317 126.834 161.480 1.00 46.32  ? 122 ASN A CB  1 
ATOM   922  C  CG  . ASN A 1 122 ? 140.090 127.166 162.294 1.00 51.88  ? 122 ASN A CG  1 
ATOM   923  O  OD1 . ASN A 1 122 ? 138.966 126.975 161.842 1.00 56.77  ? 122 ASN A OD1 1 
ATOM   924  N  ND2 . ASN A 1 122 ? 140.300 127.664 163.504 1.00 47.26  ? 122 ASN A ND2 1 
ATOM   925  N  N   . PHE A 1 123 ? 141.677 123.932 161.014 1.00 54.08  ? 123 PHE A N   1 
ATOM   926  C  CA  . PHE A 1 123 ? 141.557 122.486 161.161 1.00 54.52  ? 123 PHE A CA  1 
ATOM   927  C  C   . PHE A 1 123 ? 140.434 122.112 162.116 1.00 56.73  ? 123 PHE A C   1 
ATOM   928  O  O   . PHE A 1 123 ? 139.752 121.102 161.909 1.00 59.33  ? 123 PHE A O   1 
ATOM   929  C  CB  . PHE A 1 123 ? 142.879 121.891 161.632 1.00 55.09  ? 123 PHE A CB  1 
ATOM   930  C  CG  . PHE A 1 123 ? 142.978 120.410 161.424 1.00 55.16  ? 123 PHE A CG  1 
ATOM   931  C  CD1 . PHE A 1 123 ? 142.517 119.833 160.256 1.00 53.82  ? 123 PHE A CD1 1 
ATOM   932  C  CD2 . PHE A 1 123 ? 143.530 119.595 162.393 1.00 54.11  ? 123 PHE A CD2 1 
ATOM   933  C  CE1 . PHE A 1 123 ? 142.607 118.476 160.060 1.00 54.33  ? 123 PHE A CE1 1 
ATOM   934  C  CE2 . PHE A 1 123 ? 143.622 118.236 162.199 1.00 55.15  ? 123 PHE A CE2 1 
ATOM   935  C  CZ  . PHE A 1 123 ? 143.160 117.678 161.031 1.00 55.94  ? 123 PHE A CZ  1 
ATOM   936  N  N   . GLU A 1 124 ? 140.233 122.897 163.174 1.00 56.06  ? 124 GLU A N   1 
ATOM   937  C  CA  . GLU A 1 124 ? 139.156 122.597 164.111 1.00 54.19  ? 124 GLU A CA  1 
ATOM   938  C  C   . GLU A 1 124 ? 137.791 122.729 163.449 1.00 57.63  ? 124 GLU A C   1 
ATOM   939  O  O   . GLU A 1 124 ? 136.902 121.906 163.686 1.00 61.19  ? 124 GLU A O   1 
ATOM   940  C  CB  . GLU A 1 124 ? 139.255 123.503 165.334 1.00 56.85  ? 124 GLU A CB  1 
ATOM   941  C  CG  . GLU A 1 124 ? 140.180 122.970 166.411 1.00 63.64  ? 124 GLU A CG  1 
ATOM   942  C  CD  . GLU A 1 124 ? 141.643 123.112 166.049 1.00 65.64  ? 124 GLU A CD  1 
ATOM   943  O  OE1 . GLU A 1 124 ? 141.959 123.888 165.124 1.00 63.12  ? 124 GLU A OE1 1 
ATOM   944  O  OE2 . GLU A 1 124 ? 142.478 122.437 166.687 1.00 66.98  ? 124 GLU A OE2 1 
ATOM   945  N  N   . GLN A 1 125 ? 137.605 123.751 162.613 1.00 52.57  ? 125 GLN A N   1 
ATOM   946  C  CA  . GLN A 1 125 ? 136.331 123.912 161.922 1.00 46.86  ? 125 GLN A CA  1 
ATOM   947  C  C   . GLN A 1 125 ? 136.091 122.785 160.928 1.00 46.59  ? 125 GLN A C   1 
ATOM   948  O  O   . GLN A 1 125 ? 134.966 122.293 160.804 1.00 54.72  ? 125 GLN A O   1 
ATOM   949  C  CB  . GLN A 1 125 ? 136.279 125.263 161.218 1.00 46.92  ? 125 GLN A CB  1 
ATOM   950  C  CG  . GLN A 1 125 ? 135.843 126.402 162.107 1.00 48.97  ? 125 GLN A CG  1 
ATOM   951  C  CD  . GLN A 1 125 ? 135.939 127.741 161.420 1.00 50.61  ? 125 GLN A CD  1 
ATOM   952  O  OE1 . GLN A 1 125 ? 134.940 128.431 161.244 1.00 55.49  ? 125 GLN A OE1 1 
ATOM   953  N  NE2 . GLN A 1 125 ? 137.146 128.119 161.032 1.00 50.85  ? 125 GLN A NE2 1 
ATOM   954  N  N   . VAL A 1 126 ? 137.131 122.363 160.210 1.00 44.93  ? 126 VAL A N   1 
ATOM   955  C  CA  . VAL A 1 126 ? 136.965 121.275 159.252 1.00 47.50  ? 126 VAL A CA  1 
ATOM   956  C  C   . VAL A 1 126 ? 136.670 119.968 159.975 1.00 51.47  ? 126 VAL A C   1 
ATOM   957  O  O   . VAL A 1 126 ? 135.851 119.160 159.522 1.00 52.39  ? 126 VAL A O   1 
ATOM   958  C  CB  . VAL A 1 126 ? 138.205 121.165 158.350 1.00 44.78  ? 126 VAL A CB  1 
ATOM   959  C  CG1 . VAL A 1 126 ? 138.068 119.993 157.410 1.00 49.98  ? 126 VAL A CG1 1 
ATOM   960  C  CG2 . VAL A 1 126 ? 138.382 122.438 157.566 1.00 43.75  ? 126 VAL A CG2 1 
ATOM   961  N  N   . LYS A 1 127 ? 137.325 119.738 161.113 1.00 56.18  ? 127 LYS A N   1 
ATOM   962  C  CA  . LYS A 1 127 ? 137.037 118.546 161.899 1.00 54.00  ? 127 LYS A CA  1 
ATOM   963  C  C   . LYS A 1 127 ? 135.617 118.576 162.453 1.00 55.49  ? 127 LYS A C   1 
ATOM   964  O  O   . LYS A 1 127 ? 134.938 117.545 162.483 1.00 61.72  ? 127 LYS A O   1 
ATOM   965  C  CB  . LYS A 1 127 ? 138.059 118.407 163.022 1.00 54.72  ? 127 LYS A CB  1 
ATOM   966  C  CG  . LYS A 1 127 ? 139.256 117.551 162.654 1.00 56.93  ? 127 LYS A CG  1 
ATOM   967  C  CD  . LYS A 1 127 ? 138.828 116.135 162.327 1.00 58.67  ? 127 LYS A CD  1 
ATOM   968  C  CE  . LYS A 1 127 ? 140.013 115.261 161.975 1.00 59.35  ? 127 LYS A CE  1 
ATOM   969  N  NZ  . LYS A 1 127 ? 139.635 113.822 161.929 1.00 59.40  ? 127 LYS A NZ  1 
ATOM   970  N  N   . SER A 1 128 ? 135.150 119.747 162.894 1.00 53.41  ? 128 SER A N   1 
ATOM   971  C  CA  . SER A 1 128 ? 133.769 119.871 163.351 1.00 49.51  ? 128 SER A CA  1 
ATOM   972  C  C   . SER A 1 128 ? 132.787 119.606 162.218 1.00 54.01  ? 128 SER A C   1 
ATOM   973  O  O   . SER A 1 128 ? 131.746 118.976 162.424 1.00 61.91  ? 128 SER A O   1 
ATOM   974  C  CB  . SER A 1 128 ? 133.534 121.257 163.943 1.00 53.67  ? 128 SER A CB  1 
ATOM   975  O  OG  . SER A 1 128 ? 133.986 121.320 165.283 1.00 61.61  ? 128 SER A OG  1 
ATOM   976  N  N   . LEU A 1 129 ? 133.099 120.089 161.015 1.00 51.70  ? 129 LEU A N   1 
ATOM   977  C  CA  . LEU A 1 129 ? 132.259 119.807 159.855 1.00 47.62  ? 129 LEU A CA  1 
ATOM   978  C  C   . LEU A 1 129 ? 132.213 118.313 159.559 1.00 50.98  ? 129 LEU A C   1 
ATOM   979  O  O   . LEU A 1 129 ? 131.144 117.759 159.277 1.00 56.12  ? 129 LEU A O   1 
ATOM   980  C  CB  . LEU A 1 129 ? 132.784 120.580 158.647 1.00 49.92  ? 129 LEU A CB  1 
ATOM   981  C  CG  . LEU A 1 129 ? 131.875 120.801 157.444 1.00 52.84  ? 129 LEU A CG  1 
ATOM   982  C  CD1 . LEU A 1 129 ? 132.254 122.093 156.750 1.00 50.78  ? 129 LEU A CD1 1 
ATOM   983  C  CD2 . LEU A 1 129 ? 131.977 119.635 156.480 1.00 53.43  ? 129 LEU A CD2 1 
ATOM   984  N  N   . MET A 1 130 ? 133.367 117.647 159.619 1.00 59.96  ? 130 MET A N   1 
ATOM   985  C  CA  . MET A 1 130 ? 133.412 116.208 159.378 1.00 58.18  ? 130 MET A CA  1 
ATOM   986  C  C   . MET A 1 130 ? 132.613 115.447 160.423 1.00 57.48  ? 130 MET A C   1 
ATOM   987  O  O   . MET A 1 130 ? 131.909 114.486 160.097 1.00 60.96  ? 130 MET A O   1 
ATOM   988  C  CB  . MET A 1 130 ? 134.858 115.722 159.367 1.00 58.73  ? 130 MET A CB  1 
ATOM   989  C  CG  . MET A 1 130 ? 135.621 116.055 158.108 1.00 58.62  ? 130 MET A CG  1 
ATOM   990  S  SD  . MET A 1 130 ? 137.191 115.185 158.011 1.00 77.48  ? 130 MET A SD  1 
ATOM   991  C  CE  . MET A 1 130 ? 137.150 114.187 159.496 1.00 60.60  ? 130 MET A CE  1 
ATOM   992  N  N   . TYR A 1 131 ? 132.719 115.851 161.690 1.00 58.70  ? 131 TYR A N   1 
ATOM   993  C  CA  . TYR A 1 131 ? 131.947 115.195 162.740 1.00 58.66  ? 131 TYR A CA  1 
ATOM   994  C  C   . TYR A 1 131 ? 130.456 115.451 162.575 1.00 63.48  ? 131 TYR A C   1 
ATOM   995  O  O   . TYR A 1 131 ? 129.642 114.582 162.902 1.00 70.06  ? 131 TYR A O   1 
ATOM   996  C  CB  . TYR A 1 131 ? 132.408 115.661 164.118 1.00 58.08  ? 131 TYR A CB  1 
ATOM   997  C  CG  . TYR A 1 131 ? 133.870 115.421 164.408 1.00 61.32  ? 131 TYR A CG  1 
ATOM   998  C  CD1 . TYR A 1 131 ? 134.599 114.481 163.696 1.00 62.34  ? 131 TYR A CD1 1 
ATOM   999  C  CD2 . TYR A 1 131 ? 134.522 116.139 165.397 1.00 63.28  ? 131 TYR A CD2 1 
ATOM   1000 C  CE1 . TYR A 1 131 ? 135.934 114.266 163.961 1.00 64.61  ? 131 TYR A CE1 1 
ATOM   1001 C  CE2 . TYR A 1 131 ? 135.853 115.931 165.668 1.00 64.26  ? 131 TYR A CE2 1 
ATOM   1002 C  CZ  . TYR A 1 131 ? 136.555 114.995 164.949 1.00 64.52  ? 131 TYR A CZ  1 
ATOM   1003 O  OH  . TYR A 1 131 ? 137.886 114.790 165.224 1.00 61.67  ? 131 TYR A OH  1 
ATOM   1004 N  N   . TRP A 1 132 ? 130.079 116.636 162.094 1.00 57.12  ? 132 TRP A N   1 
ATOM   1005 C  CA  . TRP A 1 132 ? 128.678 116.890 161.781 1.00 55.34  ? 132 TRP A CA  1 
ATOM   1006 C  C   . TRP A 1 132 ? 128.192 115.971 160.670 1.00 55.15  ? 132 TRP A C   1 
ATOM   1007 O  O   . TRP A 1 132 ? 127.079 115.440 160.738 1.00 59.26  ? 132 TRP A O   1 
ATOM   1008 C  CB  . TRP A 1 132 ? 128.482 118.354 161.389 1.00 56.58  ? 132 TRP A CB  1 
ATOM   1009 C  CG  . TRP A 1 132 ? 127.061 118.710 161.081 1.00 59.13  ? 132 TRP A CG  1 
ATOM   1010 C  CD1 . TRP A 1 132 ? 126.138 119.206 161.949 1.00 60.36  ? 132 TRP A CD1 1 
ATOM   1011 C  CD2 . TRP A 1 132 ? 126.401 118.598 159.815 1.00 58.25  ? 132 TRP A CD2 1 
ATOM   1012 N  NE1 . TRP A 1 132 ? 124.942 119.407 161.305 1.00 62.25  ? 132 TRP A NE1 1 
ATOM   1013 C  CE2 . TRP A 1 132 ? 125.079 119.043 159.993 1.00 58.04  ? 132 TRP A CE2 1 
ATOM   1014 C  CE3 . TRP A 1 132 ? 126.800 118.163 158.548 1.00 58.84  ? 132 TRP A CE3 1 
ATOM   1015 C  CZ2 . TRP A 1 132 ? 124.156 119.066 158.956 1.00 54.80  ? 132 TRP A CZ2 1 
ATOM   1016 C  CZ3 . TRP A 1 132 ? 125.881 118.188 157.520 1.00 60.26  ? 132 TRP A CZ3 1 
ATOM   1017 C  CH2 . TRP A 1 132 ? 124.576 118.635 157.729 1.00 55.40  ? 132 TRP A CH2 1 
ATOM   1018 N  N   . LEU A 1 133 ? 129.012 115.776 159.635 1.00 58.00  ? 133 LEU A N   1 
ATOM   1019 C  CA  . LEU A 1 133 ? 128.631 114.871 158.554 1.00 58.33  ? 133 LEU A CA  1 
ATOM   1020 C  C   . LEU A 1 133 ? 128.443 113.450 159.064 1.00 59.31  ? 133 LEU A C   1 
ATOM   1021 O  O   . LEU A 1 133 ? 127.482 112.770 158.690 1.00 65.10  ? 133 LEU A O   1 
ATOM   1022 C  CB  . LEU A 1 133 ? 129.679 114.904 157.446 1.00 58.96  ? 133 LEU A CB  1 
ATOM   1023 C  CG  . LEU A 1 133 ? 129.155 114.955 156.012 1.00 56.53  ? 133 LEU A CG  1 
ATOM   1024 C  CD1 . LEU A 1 133 ? 128.264 116.164 155.806 1.00 57.76  ? 133 LEU A CD1 1 
ATOM   1025 C  CD2 . LEU A 1 133 ? 130.316 114.976 155.040 1.00 58.59  ? 133 LEU A CD2 1 
ATOM   1026 N  N   . ASP A 1 134 ? 129.351 112.983 159.912 1.00 60.92  ? 134 ASP A N   1 
ATOM   1027 C  CA  . ASP A 1 134 ? 129.232 111.668 160.528 1.00 63.12  ? 134 ASP A CA  1 
ATOM   1028 C  C   . ASP A 1 134 ? 129.743 111.728 161.960 1.00 64.18  ? 134 ASP A C   1 
ATOM   1029 O  O   . ASP A 1 134 ? 130.955 111.830 162.182 1.00 66.95  ? 134 ASP A O   1 
ATOM   1030 C  CB  . ASP A 1 134 ? 130.004 110.618 159.732 1.00 67.09  ? 134 ASP A CB  1 
ATOM   1031 C  CG  . ASP A 1 134 ? 129.592 109.203 160.085 1.00 69.90  ? 134 ASP A CG  1 
ATOM   1032 O  OD1 . ASP A 1 134 ? 128.962 109.008 161.143 1.00 67.74  ? 134 ASP A OD1 1 
ATOM   1033 O  OD2 . ASP A 1 134 ? 129.901 108.279 159.305 1.00 70.96  ? 134 ASP A OD2 1 
ATOM   1034 N  N   . PRO A 1 135 ? 128.855 111.674 162.954 1.00 70.57  ? 135 PRO A N   1 
ATOM   1035 C  CA  . PRO A 1 135 ? 129.318 111.697 164.352 1.00 70.91  ? 135 PRO A CA  1 
ATOM   1036 C  C   . PRO A 1 135 ? 130.206 110.522 164.717 1.00 74.23  ? 135 PRO A C   1 
ATOM   1037 O  O   . PRO A 1 135 ? 130.987 110.632 165.669 1.00 71.70  ? 135 PRO A O   1 
ATOM   1038 C  CB  . PRO A 1 135 ? 128.020 111.686 165.171 1.00 71.84  ? 135 PRO A CB  1 
ATOM   1039 C  CG  . PRO A 1 135 ? 126.901 111.785 164.214 1.00 73.26  ? 135 PRO A CG  1 
ATOM   1040 C  CD  . PRO A 1 135 ? 127.391 111.683 162.818 1.00 70.03  ? 135 PRO A CD  1 
ATOM   1041 N  N   . ASN A 1 136 ? 130.113 109.403 163.997 1.00 83.37  ? 136 ASN A N   1 
ATOM   1042 C  CA  . ASN A 1 136 ? 130.955 108.248 164.281 1.00 83.56  ? 136 ASN A CA  1 
ATOM   1043 C  C   . ASN A 1 136 ? 132.415 108.471 163.913 1.00 83.11  ? 136 ASN A C   1 
ATOM   1044 O  O   . ASN A 1 136 ? 133.259 107.651 164.286 1.00 81.33  ? 136 ASN A O   1 
ATOM   1045 C  CB  . ASN A 1 136 ? 130.422 107.017 163.546 1.00 82.18  ? 136 ASN A CB  1 
ATOM   1046 C  CG  . ASN A 1 136 ? 129.074 106.567 164.068 1.00 84.40  ? 136 ASN A CG  1 
ATOM   1047 O  OD1 . ASN A 1 136 ? 128.212 107.387 164.378 1.00 82.92  ? 136 ASN A OD1 1 
ATOM   1048 N  ND2 . ASN A 1 136 ? 128.886 105.257 164.169 1.00 84.79  ? 136 ASN A ND2 1 
ATOM   1049 N  N   . LEU A 1 137 ? 132.732 109.543 163.188 1.00 78.16  ? 137 LEU A N   1 
ATOM   1050 C  CA  . LEU A 1 137 ? 134.119 109.854 162.873 1.00 74.27  ? 137 LEU A CA  1 
ATOM   1051 C  C   . LEU A 1 137 ? 134.865 110.457 164.053 1.00 74.56  ? 137 LEU A C   1 
ATOM   1052 O  O   . LEU A 1 137 ? 136.100 110.439 164.064 1.00 74.13  ? 137 LEU A O   1 
ATOM   1053 C  CB  . LEU A 1 137 ? 134.186 110.818 161.689 1.00 70.64  ? 137 LEU A CB  1 
ATOM   1054 C  CG  . LEU A 1 137 ? 133.984 110.217 160.301 1.00 69.44  ? 137 LEU A CG  1 
ATOM   1055 C  CD1 . LEU A 1 137 ? 134.199 111.270 159.233 1.00 71.52  ? 137 LEU A CD1 1 
ATOM   1056 C  CD2 . LEU A 1 137 ? 134.919 109.045 160.094 1.00 73.12  ? 137 LEU A CD2 1 
ATOM   1057 N  N   . ARG A 1 138 ? 134.145 110.992 165.039 1.00 78.57  ? 138 ARG A N   1 
ATOM   1058 C  CA  . ARG A 1 138 ? 134.800 111.620 166.180 1.00 78.24  ? 138 ARG A CA  1 
ATOM   1059 C  C   . ARG A 1 138 ? 135.465 110.584 167.075 1.00 81.03  ? 138 ARG A C   1 
ATOM   1060 O  O   . ARG A 1 138 ? 136.594 110.784 167.536 1.00 81.09  ? 138 ARG A O   1 
ATOM   1061 C  CB  . ARG A 1 138 ? 133.784 112.441 166.972 1.00 78.38  ? 138 ARG A CB  1 
ATOM   1062 C  CG  . ARG A 1 138 ? 134.394 113.414 167.963 1.00 77.91  ? 138 ARG A CG  1 
ATOM   1063 C  CD  . ARG A 1 138 ? 133.367 113.874 168.984 1.00 79.43  ? 138 ARG A CD  1 
ATOM   1064 N  NE  . ARG A 1 138 ? 132.645 115.060 168.540 1.00 81.97  ? 138 ARG A NE  1 
ATOM   1065 C  CZ  . ARG A 1 138 ? 131.491 115.035 167.888 1.00 81.98  ? 138 ARG A CZ  1 
ATOM   1066 N  NH1 . ARG A 1 138 ? 130.888 113.896 167.594 1.00 84.09  ? 138 ARG A NH1 1 
ATOM   1067 N  NH2 . ARG A 1 138 ? 130.926 116.183 167.525 1.00 79.39  ? 138 ARG A NH2 1 
ATOM   1068 N  N   . TYR A 1 139 ? 134.779 109.471 167.328 1.00 90.96  ? 139 TYR A N   1 
ATOM   1069 C  CA  . TYR A 1 139 ? 135.281 108.467 168.257 1.00 91.95  ? 139 TYR A CA  1 
ATOM   1070 C  C   . TYR A 1 139 ? 136.379 107.611 167.642 1.00 90.62  ? 139 TYR A C   1 
ATOM   1071 O  O   . TYR A 1 139 ? 137.250 107.117 168.366 1.00 90.91  ? 139 TYR A O   1 
ATOM   1072 C  CB  . TYR A 1 139 ? 134.119 107.602 168.744 1.00 90.39  ? 139 TYR A CB  1 
ATOM   1073 C  CG  . TYR A 1 139 ? 132.831 108.386 168.870 1.00 93.40  ? 139 TYR A CG  1 
ATOM   1074 C  CD1 . TYR A 1 139 ? 132.752 109.501 169.698 1.00 92.05  ? 139 TYR A CD1 1 
ATOM   1075 C  CD2 . TYR A 1 139 ? 131.702 108.027 168.145 1.00 91.69  ? 139 TYR A CD2 1 
ATOM   1076 C  CE1 . TYR A 1 139 ? 131.583 110.229 169.809 1.00 90.25  ? 139 TYR A CE1 1 
ATOM   1077 C  CE2 . TYR A 1 139 ? 130.526 108.750 168.252 1.00 92.36  ? 139 TYR A CE2 1 
ATOM   1078 C  CZ  . TYR A 1 139 ? 130.474 109.850 169.084 1.00 92.71  ? 139 TYR A CZ  1 
ATOM   1079 O  OH  . TYR A 1 139 ? 129.308 110.572 169.193 1.00 90.73  ? 139 TYR A OH  1 
ATOM   1080 N  N   . ALA A 1 140 ? 136.361 107.431 166.326 1.00 86.48  ? 140 ALA A N   1 
ATOM   1081 C  CA  . ALA A 1 140 ? 137.399 106.667 165.643 1.00 87.52  ? 140 ALA A CA  1 
ATOM   1082 C  C   . ALA A 1 140 ? 138.735 107.402 165.692 1.00 87.44  ? 140 ALA A C   1 
ATOM   1083 O  O   . ALA A 1 140 ? 139.239 107.864 164.668 1.00 87.57  ? 140 ALA A O   1 
ATOM   1084 C  CB  . ALA A 1 140 ? 136.998 106.394 164.204 1.00 87.38  ? 140 ALA A CB  1 
ATOM   1085 N  N   . GLU A 1 159 ? 146.645 81.935  150.899 1.00 130.36 ? 159 GLU A N   1 
ATOM   1086 C  CA  . GLU A 1 159 ? 145.650 82.080  151.955 1.00 131.23 ? 159 GLU A CA  1 
ATOM   1087 C  C   . GLU A 1 159 ? 145.531 83.535  152.389 1.00 131.08 ? 159 GLU A C   1 
ATOM   1088 O  O   . GLU A 1 159 ? 144.452 84.124  152.331 1.00 130.47 ? 159 GLU A O   1 
ATOM   1089 C  CB  . GLU A 1 159 ? 146.005 81.197  153.153 1.00 130.71 ? 159 GLU A CB  1 
ATOM   1090 C  CG  . GLU A 1 159 ? 145.836 79.708  152.899 1.00 130.95 ? 159 GLU A CG  1 
ATOM   1091 C  CD  . GLU A 1 159 ? 147.023 79.096  152.179 1.00 131.25 ? 159 GLU A CD  1 
ATOM   1092 O  OE1 . GLU A 1 159 ? 148.004 79.825  151.917 1.00 131.18 ? 159 GLU A OE1 1 
ATOM   1093 O  OE2 . GLU A 1 159 ? 146.975 77.886  151.873 1.00 131.17 ? 159 GLU A OE2 1 
ATOM   1094 N  N   . ARG A 1 160 ? 146.653 84.107  152.834 1.00 127.76 ? 160 ARG A N   1 
ATOM   1095 C  CA  . ARG A 1 160 ? 146.670 85.517  153.210 1.00 127.72 ? 160 ARG A CA  1 
ATOM   1096 C  C   . ARG A 1 160 ? 146.416 86.415  152.006 1.00 127.25 ? 160 ARG A C   1 
ATOM   1097 O  O   . ARG A 1 160 ? 145.689 87.410  152.109 1.00 125.34 ? 160 ARG A O   1 
ATOM   1098 C  CB  . ARG A 1 160 ? 148.005 85.860  153.871 1.00 126.45 ? 160 ARG A CB  1 
ATOM   1099 C  CG  . ARG A 1 160 ? 148.188 87.329  154.214 1.00 126.42 ? 160 ARG A CG  1 
ATOM   1100 C  CD  . ARG A 1 160 ? 149.533 87.551  154.882 1.00 127.06 ? 160 ARG A CD  1 
ATOM   1101 N  NE  . ARG A 1 160 ? 149.973 88.938  154.806 1.00 126.98 ? 160 ARG A NE  1 
ATOM   1102 C  CZ  . ARG A 1 160 ? 151.128 89.381  155.284 1.00 126.73 ? 160 ARG A CZ  1 
ATOM   1103 N  NH1 . ARG A 1 160 ? 151.982 88.570  155.887 1.00 125.23 ? 160 ARG A NH1 1 
ATOM   1104 N  NH2 . ARG A 1 160 ? 151.434 90.668  155.153 1.00 126.83 ? 160 ARG A NH2 1 
ATOM   1105 N  N   . ILE A 1 161 ? 147.006 86.080  150.857 1.00 124.32 ? 161 ILE A N   1 
ATOM   1106 C  CA  . ILE A 1 161 ? 146.787 86.868  149.647 1.00 123.63 ? 161 ILE A CA  1 
ATOM   1107 C  C   . ILE A 1 161 ? 145.323 86.817  149.236 1.00 123.37 ? 161 ILE A C   1 
ATOM   1108 O  O   . ILE A 1 161 ? 144.764 87.806  148.747 1.00 123.25 ? 161 ILE A O   1 
ATOM   1109 C  CB  . ILE A 1 161 ? 147.712 86.380  148.518 1.00 122.58 ? 161 ILE A CB  1 
ATOM   1110 C  CG1 . ILE A 1 161 ? 149.124 86.136  149.055 1.00 123.17 ? 161 ILE A CG1 1 
ATOM   1111 C  CG2 . ILE A 1 161 ? 147.737 87.382  147.377 1.00 121.55 ? 161 ILE A CG2 1 
ATOM   1112 C  CD1 . ILE A 1 161 ? 150.133 85.779  147.987 1.00 122.79 ? 161 ILE A CD1 1 
ATOM   1113 N  N   . ILE A 1 162 ? 144.679 85.662  149.420 1.00 122.93 ? 162 ILE A N   1 
ATOM   1114 C  CA  . ILE A 1 162 ? 143.262 85.539  149.091 1.00 123.09 ? 162 ILE A CA  1 
ATOM   1115 C  C   . ILE A 1 162 ? 142.430 86.465  149.968 1.00 123.44 ? 162 ILE A C   1 
ATOM   1116 O  O   . ILE A 1 162 ? 141.477 87.099  149.500 1.00 123.11 ? 162 ILE A O   1 
ATOM   1117 C  CB  . ILE A 1 162 ? 142.809 84.074  149.222 1.00 123.12 ? 162 ILE A CB  1 
ATOM   1118 C  CG1 . ILE A 1 162 ? 143.914 83.133  148.742 1.00 123.26 ? 162 ILE A CG1 1 
ATOM   1119 C  CG2 . ILE A 1 162 ? 141.536 83.840  148.429 1.00 122.48 ? 162 ILE A CG2 1 
ATOM   1120 C  CD1 . ILE A 1 162 ? 143.573 81.666  148.886 1.00 122.75 ? 162 ILE A CD1 1 
ATOM   1121 N  N   . SER A 1 163 ? 142.772 86.554  151.255 1.00 124.50 ? 163 SER A N   1 
ATOM   1122 C  CA  . SER A 1 163 ? 142.062 87.452  152.156 1.00 124.68 ? 163 SER A CA  1 
ATOM   1123 C  C   . SER A 1 163 ? 142.361 88.917  151.868 1.00 124.23 ? 163 SER A C   1 
ATOM   1124 O  O   . SER A 1 163 ? 141.563 89.784  152.241 1.00 123.41 ? 163 SER A O   1 
ATOM   1125 C  CB  . SER A 1 163 ? 142.408 87.122  153.609 1.00 124.53 ? 163 SER A CB  1 
ATOM   1126 O  OG  . SER A 1 163 ? 143.761 87.426  153.898 1.00 125.01 ? 163 SER A OG  1 
ATOM   1127 N  N   . HIS A 1 164 ? 143.493 89.214  151.223 1.00 122.98 ? 164 HIS A N   1 
ATOM   1128 C  CA  . HIS A 1 164 ? 143.803 90.595  150.867 1.00 123.14 ? 164 HIS A CA  1 
ATOM   1129 C  C   . HIS A 1 164 ? 142.813 91.138  149.845 1.00 122.77 ? 164 HIS A C   1 
ATOM   1130 O  O   . HIS A 1 164 ? 142.404 92.302  149.928 1.00 122.38 ? 164 HIS A O   1 
ATOM   1131 C  CB  . HIS A 1 164 ? 145.231 90.693  150.331 1.00 123.50 ? 164 HIS A CB  1 
ATOM   1132 C  CG  . HIS A 1 164 ? 146.242 91.073  151.368 1.00 125.41 ? 164 HIS A CG  1 
ATOM   1133 N  ND1 . HIS A 1 164 ? 146.477 90.312  152.493 1.00 124.24 ? 164 HIS A ND1 1 
ATOM   1134 C  CD2 . HIS A 1 164 ? 147.083 92.131  151.447 1.00 124.64 ? 164 HIS A CD2 1 
ATOM   1135 C  CE1 . HIS A 1 164 ? 147.418 90.885  153.221 1.00 123.64 ? 164 HIS A CE1 1 
ATOM   1136 N  NE2 . HIS A 1 164 ? 147.803 91.991  152.609 1.00 124.71 ? 164 HIS A NE2 1 
ATOM   1137 N  N   . PHE A 1 165 ? 142.419 90.314  148.876 1.00 118.14 ? 165 PHE A N   1 
ATOM   1138 C  CA  . PHE A 1 165 ? 141.488 90.736  147.834 1.00 117.83 ? 165 PHE A CA  1 
ATOM   1139 C  C   . PHE A 1 165 ? 140.116 90.993  148.443 1.00 116.47 ? 165 PHE A C   1 
ATOM   1140 O  O   . PHE A 1 165 ? 139.416 90.056  148.838 1.00 115.71 ? 165 PHE A O   1 
ATOM   1141 C  CB  . PHE A 1 165 ? 141.405 89.678  146.740 1.00 116.49 ? 165 PHE A CB  1 
ATOM   1142 C  CG  . PHE A 1 165 ? 142.691 89.473  146.001 1.00 116.01 ? 165 PHE A CG  1 
ATOM   1143 C  CD1 . PHE A 1 165 ? 143.282 90.517  145.311 1.00 115.71 ? 165 PHE A CD1 1 
ATOM   1144 C  CD2 . PHE A 1 165 ? 143.315 88.238  146.002 1.00 116.03 ? 165 PHE A CD2 1 
ATOM   1145 C  CE1 . PHE A 1 165 ? 144.470 90.331  144.631 1.00 116.55 ? 165 PHE A CE1 1 
ATOM   1146 C  CE2 . PHE A 1 165 ? 144.501 88.046  145.325 1.00 116.40 ? 165 PHE A CE2 1 
ATOM   1147 C  CZ  . PHE A 1 165 ? 145.079 89.094  144.639 1.00 117.05 ? 165 PHE A CZ  1 
ATOM   1148 N  N   . ASP A 1 166 ? 139.731 92.261  148.515 1.00 103.72 ? 166 ASP A N   1 
ATOM   1149 C  CA  . ASP A 1 166 ? 138.434 92.680  149.021 1.00 102.20 ? 166 ASP A CA  1 
ATOM   1150 C  C   . ASP A 1 166 ? 137.695 93.437  147.921 1.00 101.06 ? 166 ASP A C   1 
ATOM   1151 O  O   . ASP A 1 166 ? 138.127 93.471  146.766 1.00 103.04 ? 166 ASP A O   1 
ATOM   1152 C  CB  . ASP A 1 166 ? 138.600 93.533  150.280 1.00 102.17 ? 166 ASP A CB  1 
ATOM   1153 C  CG  . ASP A 1 166 ? 139.822 94.422  150.218 1.00 104.57 ? 166 ASP A CG  1 
ATOM   1154 O  OD1 . ASP A 1 166 ? 140.572 94.328  149.225 1.00 102.56 ? 166 ASP A OD1 1 
ATOM   1155 O  OD2 . ASP A 1 166 ? 140.035 95.213  151.160 1.00 105.40 ? 166 ASP A OD2 1 
ATOM   1156 N  N   . ILE A 1 167 ? 136.563 94.041  148.286 1.00 93.02  ? 167 ILE A N   1 
ATOM   1157 C  CA  . ILE A 1 167 ? 135.842 94.875  147.331 1.00 93.62  ? 167 ILE A CA  1 
ATOM   1158 C  C   . ILE A 1 167 ? 136.686 96.075  146.931 1.00 93.74  ? 167 ILE A C   1 
ATOM   1159 O  O   . ILE A 1 167 ? 136.535 96.612  145.827 1.00 95.87  ? 167 ILE A O   1 
ATOM   1160 C  CB  . ILE A 1 167 ? 134.477 95.299  147.910 1.00 95.22  ? 167 ILE A CB  1 
ATOM   1161 C  CG1 . ILE A 1 167 ? 133.611 95.946  146.828 1.00 93.61  ? 167 ILE A CG1 1 
ATOM   1162 C  CG2 . ILE A 1 167 ? 134.657 96.236  149.093 1.00 94.84  ? 167 ILE A CG2 1 
ATOM   1163 C  CD1 . ILE A 1 167 ? 132.154 96.062  147.203 1.00 92.53  ? 167 ILE A CD1 1 
ATOM   1164 N  N   . PHE A 1 168 ? 137.599 96.504  147.805 1.00 88.97  ? 168 PHE A N   1 
ATOM   1165 C  CA  . PHE A 1 168 ? 138.487 97.610  147.463 1.00 88.42  ? 168 PHE A CA  1 
ATOM   1166 C  C   . PHE A 1 168 ? 139.478 97.209  146.377 1.00 88.29  ? 168 PHE A C   1 
ATOM   1167 O  O   . PHE A 1 168 ? 139.779 98.006  145.484 1.00 88.13  ? 168 PHE A O   1 
ATOM   1168 C  CB  . PHE A 1 168 ? 139.216 98.098  148.713 1.00 87.99  ? 168 PHE A CB  1 
ATOM   1169 C  CG  . PHE A 1 168 ? 138.310 98.729  149.730 1.00 89.23  ? 168 PHE A CG  1 
ATOM   1170 C  CD1 . PHE A 1 168 ? 137.273 99.554  149.333 1.00 88.85  ? 168 PHE A CD1 1 
ATOM   1171 C  CD2 . PHE A 1 168 ? 138.490 98.490  151.079 1.00 89.99  ? 168 PHE A CD2 1 
ATOM   1172 C  CE1 . PHE A 1 168 ? 136.436 100.132 150.262 1.00 90.73  ? 168 PHE A CE1 1 
ATOM   1173 C  CE2 . PHE A 1 168 ? 137.656 99.066  152.012 1.00 90.40  ? 168 PHE A CE2 1 
ATOM   1174 C  CZ  . PHE A 1 168 ? 136.628 99.887  151.603 1.00 90.56  ? 168 PHE A CZ  1 
ATOM   1175 N  N   . ALA A 1 169 ? 139.995 95.980  146.435 1.00 87.97  ? 169 ALA A N   1 
ATOM   1176 C  CA  . ALA A 1 169 ? 140.875 95.501  145.373 1.00 87.40  ? 169 ALA A CA  1 
ATOM   1177 C  C   . ALA A 1 169 ? 140.134 95.408  144.047 1.00 82.89  ? 169 ALA A C   1 
ATOM   1178 O  O   . ALA A 1 169 ? 140.683 95.741  142.992 1.00 84.20  ? 169 ALA A O   1 
ATOM   1179 C  CB  . ALA A 1 169 ? 141.467 94.145  145.752 1.00 87.58  ? 169 ALA A CB  1 
ATOM   1180 N  N   . PHE A 1 170 ? 138.884 94.948  144.086 1.00 82.12  ? 170 PHE A N   1 
ATOM   1181 C  CA  . PHE A 1 170 ? 138.068 94.881  142.880 1.00 81.05  ? 170 PHE A CA  1 
ATOM   1182 C  C   . PHE A 1 170 ? 137.846 96.275  142.307 1.00 82.99  ? 170 PHE A C   1 
ATOM   1183 O  O   . PHE A 1 170 ? 137.936 96.483  141.089 1.00 85.55  ? 170 PHE A O   1 
ATOM   1184 C  CB  . PHE A 1 170 ? 136.738 94.207  143.221 1.00 83.14  ? 170 PHE A CB  1 
ATOM   1185 C  CG  . PHE A 1 170 ? 136.007 93.639  142.042 1.00 83.52  ? 170 PHE A CG  1 
ATOM   1186 C  CD1 . PHE A 1 170 ? 136.699 93.147  140.949 1.00 85.25  ? 170 PHE A CD1 1 
ATOM   1187 C  CD2 . PHE A 1 170 ? 134.626 93.560  142.045 1.00 83.81  ? 170 PHE A CD2 1 
ATOM   1188 C  CE1 . PHE A 1 170 ? 136.025 92.602  139.875 1.00 85.08  ? 170 PHE A CE1 1 
ATOM   1189 C  CE2 . PHE A 1 170 ? 133.945 93.023  140.972 1.00 85.60  ? 170 PHE A CE2 1 
ATOM   1190 C  CZ  . PHE A 1 170 ? 134.645 92.542  139.886 1.00 85.35  ? 170 PHE A CZ  1 
ATOM   1191 N  N   . GLY A 1 171 ? 137.574 97.249  143.179 1.00 82.41  ? 171 GLY A N   1 
ATOM   1192 C  CA  . GLY A 1 171 ? 137.412 98.619  142.723 1.00 78.88  ? 171 GLY A CA  1 
ATOM   1193 C  C   . GLY A 1 171 ? 138.685 99.199  142.137 1.00 81.36  ? 171 GLY A C   1 
ATOM   1194 O  O   . GLY A 1 171 ? 138.644 99.931  141.151 1.00 82.24  ? 171 GLY A O   1 
ATOM   1195 N  N   . HIS A 1 172 ? 139.832 98.884  142.741 1.00 82.16  ? 172 HIS A N   1 
ATOM   1196 C  CA  . HIS A 1 172 ? 141.111 99.338  142.200 1.00 80.56  ? 172 HIS A CA  1 
ATOM   1197 C  C   . HIS A 1 172 ? 141.373 98.732  140.827 1.00 77.12  ? 172 HIS A C   1 
ATOM   1198 O  O   . HIS A 1 172 ? 141.841 99.421  139.911 1.00 77.63  ? 172 HIS A O   1 
ATOM   1199 C  CB  . HIS A 1 172 ? 142.239 98.978  143.164 1.00 79.65  ? 172 HIS A CB  1 
ATOM   1200 C  CG  . HIS A 1 172 ? 143.220 100.084 143.389 1.00 83.07  ? 172 HIS A CG  1 
ATOM   1201 N  ND1 . HIS A 1 172 ? 143.875 100.722 142.358 1.00 84.81  ? 172 HIS A ND1 1 
ATOM   1202 C  CD2 . HIS A 1 172 ? 143.657 100.667 144.530 1.00 82.95  ? 172 HIS A CD2 1 
ATOM   1203 C  CE1 . HIS A 1 172 ? 144.673 101.650 142.854 1.00 83.52  ? 172 HIS A CE1 1 
ATOM   1204 N  NE2 . HIS A 1 172 ? 144.560 101.637 144.170 1.00 86.23  ? 172 HIS A NE2 1 
ATOM   1205 N  N   . PHE A 1 173 ? 141.079 97.441  140.671 1.00 67.46  ? 173 PHE A N   1 
ATOM   1206 C  CA  . PHE A 1 173 ? 141.247 96.783  139.381 1.00 63.87  ? 173 PHE A CA  1 
ATOM   1207 C  C   . PHE A 1 173 ? 140.374 97.436  138.320 1.00 63.20  ? 173 PHE A C   1 
ATOM   1208 O  O   . PHE A 1 173 ? 140.834 97.722  137.208 1.00 69.47  ? 173 PHE A O   1 
ATOM   1209 C  CB  . PHE A 1 173 ? 140.920 95.296  139.518 1.00 64.31  ? 173 PHE A CB  1 
ATOM   1210 C  CG  . PHE A 1 173 ? 140.627 94.611  138.217 1.00 64.67  ? 173 PHE A CG  1 
ATOM   1211 C  CD1 . PHE A 1 173 ? 141.648 94.077  137.459 1.00 63.68  ? 173 PHE A CD1 1 
ATOM   1212 C  CD2 . PHE A 1 173 ? 139.328 94.481  137.763 1.00 66.97  ? 173 PHE A CD2 1 
ATOM   1213 C  CE1 . PHE A 1 173 ? 141.383 93.443  136.267 1.00 61.18  ? 173 PHE A CE1 1 
ATOM   1214 C  CE2 . PHE A 1 173 ? 139.059 93.850  136.571 1.00 66.76  ? 173 PHE A CE2 1 
ATOM   1215 C  CZ  . PHE A 1 173 ? 140.088 93.329  135.823 1.00 63.01  ? 173 PHE A CZ  1 
ATOM   1216 N  N   . TRP A 1 174 ? 139.108 97.697  138.648 1.00 59.76  ? 174 TRP A N   1 
ATOM   1217 C  CA  . TRP A 1 174 ? 138.231 98.310  137.658 1.00 61.67  ? 174 TRP A CA  1 
ATOM   1218 C  C   . TRP A 1 174 ? 138.602 99.763  137.397 1.00 64.48  ? 174 TRP A C   1 
ATOM   1219 O  O   . TRP A 1 174 ? 138.413 100.256 136.281 1.00 68.54  ? 174 TRP A O   1 
ATOM   1220 C  CB  . TRP A 1 174 ? 136.773 98.196  138.090 1.00 66.59  ? 174 TRP A CB  1 
ATOM   1221 C  CG  . TRP A 1 174 ? 136.185 96.871  137.756 1.00 66.51  ? 174 TRP A CG  1 
ATOM   1222 C  CD1 . TRP A 1 174 ? 135.811 95.902  138.630 1.00 68.01  ? 174 TRP A CD1 1 
ATOM   1223 C  CD2 . TRP A 1 174 ? 135.931 96.351  136.445 1.00 68.07  ? 174 TRP A CD2 1 
ATOM   1224 N  NE1 . TRP A 1 174 ? 135.323 94.817  137.950 1.00 68.55  ? 174 TRP A NE1 1 
ATOM   1225 C  CE2 . TRP A 1 174 ? 135.389 95.065  136.607 1.00 68.60  ? 174 TRP A CE2 1 
ATOM   1226 C  CE3 . TRP A 1 174 ? 136.101 96.852  135.153 1.00 68.26  ? 174 TRP A CE3 1 
ATOM   1227 C  CZ2 . TRP A 1 174 ? 135.016 94.272  135.529 1.00 68.99  ? 174 TRP A CZ2 1 
ATOM   1228 C  CZ3 . TRP A 1 174 ? 135.730 96.063  134.084 1.00 68.59  ? 174 TRP A CZ3 1 
ATOM   1229 C  CH2 . TRP A 1 174 ? 135.193 94.787  134.277 1.00 69.61  ? 174 TRP A CH2 1 
ATOM   1230 N  N   . GLY A 1 175 ? 139.135 100.462 138.397 1.00 55.23  ? 175 GLY A N   1 
ATOM   1231 C  CA  . GLY A 1 175 ? 139.611 101.812 138.161 1.00 50.70  ? 175 GLY A CA  1 
ATOM   1232 C  C   . GLY A 1 175 ? 140.784 101.845 137.206 1.00 52.40  ? 175 GLY A C   1 
ATOM   1233 O  O   . GLY A 1 175 ? 140.851 102.696 136.318 1.00 57.57  ? 175 GLY A O   1 
ATOM   1234 N  N   . TRP A 1 176 ? 141.722 100.912 137.367 1.00 56.96  ? 176 TRP A N   1 
ATOM   1235 C  CA  . TRP A 1 176 ? 142.839 100.834 136.431 1.00 47.03  ? 176 TRP A CA  1 
ATOM   1236 C  C   . TRP A 1 176 ? 142.370 100.425 135.042 1.00 49.67  ? 176 TRP A C   1 
ATOM   1237 O  O   . TRP A 1 176 ? 142.888 100.923 134.037 1.00 53.43  ? 176 TRP A O   1 
ATOM   1238 C  CB  . TRP A 1 176 ? 143.898 99.869  136.952 1.00 48.05  ? 176 TRP A CB  1 
ATOM   1239 C  CG  . TRP A 1 176 ? 144.963 100.569 137.703 1.00 49.84  ? 176 TRP A CG  1 
ATOM   1240 C  CD1 . TRP A 1 176 ? 145.258 100.431 139.021 1.00 52.52  ? 176 TRP A CD1 1 
ATOM   1241 C  CD2 . TRP A 1 176 ? 145.868 101.547 137.187 1.00 48.95  ? 176 TRP A CD2 1 
ATOM   1242 N  NE1 . TRP A 1 176 ? 146.298 101.256 139.361 1.00 54.23  ? 176 TRP A NE1 1 
ATOM   1243 C  CE2 . TRP A 1 176 ? 146.691 101.953 138.249 1.00 51.81  ? 176 TRP A CE2 1 
ATOM   1244 C  CE3 . TRP A 1 176 ? 146.066 102.117 135.927 1.00 49.97  ? 176 TRP A CE3 1 
ATOM   1245 C  CZ2 . TRP A 1 176 ? 147.695 102.899 138.093 1.00 50.72  ? 176 TRP A CZ2 1 
ATOM   1246 C  CZ3 . TRP A 1 176 ? 147.060 103.055 135.776 1.00 50.59  ? 176 TRP A CZ3 1 
ATOM   1247 C  CH2 . TRP A 1 176 ? 147.864 103.435 136.851 1.00 49.76  ? 176 TRP A CH2 1 
ATOM   1248 N  N   . ALA A 1 177 ? 141.390 99.522  134.964 1.00 49.87  ? 177 ALA A N   1 
ATOM   1249 C  CA  . ALA A 1 177 ? 140.822 99.170  133.668 1.00 46.76  ? 177 ALA A CA  1 
ATOM   1250 C  C   . ALA A 1 177 ? 140.193 100.375 132.985 1.00 50.38  ? 177 ALA A C   1 
ATOM   1251 O  O   . ALA A 1 177 ? 140.441 100.616 131.799 1.00 58.07  ? 177 ALA A O   1 
ATOM   1252 C  CB  . ALA A 1 177 ? 139.792 98.055  133.832 1.00 46.43  ? 177 ALA A CB  1 
ATOM   1253 N  N   . MET A 1 178 ? 139.407 101.162 133.720 1.00 47.83  ? 178 MET A N   1 
ATOM   1254 C  CA  . MET A 1 178 ? 138.799 102.356 133.146 1.00 44.50  ? 178 MET A CA  1 
ATOM   1255 C  C   . MET A 1 178 ? 139.848 103.388 132.749 1.00 45.63  ? 178 MET A C   1 
ATOM   1256 O  O   . MET A 1 178 ? 139.705 104.049 131.716 1.00 46.78  ? 178 MET A O   1 
ATOM   1257 C  CB  . MET A 1 178 ? 137.796 102.959 134.127 1.00 44.94  ? 178 MET A CB  1 
ATOM   1258 C  CG  . MET A 1 178 ? 137.226 104.299 133.693 1.00 50.92  ? 178 MET A CG  1 
ATOM   1259 S  SD  . MET A 1 178 ? 137.075 105.458 135.063 1.00 69.56  ? 178 MET A SD  1 
ATOM   1260 C  CE  . MET A 1 178 ? 138.445 106.556 134.726 1.00 50.79  ? 178 MET A CE  1 
ATOM   1261 N  N   . LYS A 1 179 ? 140.901 103.551 133.552 1.00 45.80  ? 179 LYS A N   1 
ATOM   1262 C  CA  . LYS A 1 179 ? 141.954 104.496 133.195 1.00 40.93  ? 179 LYS A CA  1 
ATOM   1263 C  C   . LYS A 1 179 ? 142.648 104.078 131.907 1.00 42.29  ? 179 LYS A C   1 
ATOM   1264 O  O   . LYS A 1 179 ? 142.753 104.870 130.966 1.00 53.43  ? 179 LYS A O   1 
ATOM   1265 C  CB  . LYS A 1 179 ? 142.970 104.618 134.328 1.00 42.60  ? 179 LYS A CB  1 
ATOM   1266 C  CG  . LYS A 1 179 ? 142.472 105.353 135.554 1.00 46.56  ? 179 LYS A CG  1 
ATOM   1267 C  CD  . LYS A 1 179 ? 143.314 104.980 136.759 1.00 48.25  ? 179 LYS A CD  1 
ATOM   1268 C  CE  . LYS A 1 179 ? 142.702 105.469 138.055 1.00 47.55  ? 179 LYS A CE  1 
ATOM   1269 N  NZ  . LYS A 1 179 ? 143.428 104.917 139.232 1.00 49.83  ? 179 LYS A NZ  1 
ATOM   1270 N  N   . ALA A 1 180 ? 143.110 102.828 131.840 1.00 41.39  ? 180 ALA A N   1 
ATOM   1271 C  CA  . ALA A 1 180 ? 143.758 102.336 130.632 1.00 38.17  ? 180 ALA A CA  1 
ATOM   1272 C  C   . ALA A 1 180 ? 142.815 102.336 129.440 1.00 40.10  ? 180 ALA A C   1 
ATOM   1273 O  O   . ALA A 1 180 ? 143.279 102.336 128.296 1.00 30.24  ? 180 ALA A O   1 
ATOM   1274 C  CB  . ALA A 1 180 ? 144.304 100.930 130.867 1.00 39.36  ? 180 ALA A CB  1 
ATOM   1275 N  N   . LEU A 1 181 ? 141.504 102.335 129.685 1.00 48.71  ? 181 LEU A N   1 
ATOM   1276 C  CA  . LEU A 1 181 ? 140.543 102.429 128.595 1.00 35.39  ? 181 LEU A CA  1 
ATOM   1277 C  C   . LEU A 1 181 ? 140.605 103.782 127.898 1.00 37.15  ? 181 LEU A C   1 
ATOM   1278 O  O   . LEU A 1 181 ? 140.299 103.878 126.706 1.00 43.27  ? 181 LEU A O   1 
ATOM   1279 C  CB  . LEU A 1 181 ? 139.137 102.157 129.124 1.00 34.32  ? 181 LEU A CB  1 
ATOM   1280 C  CG  . LEU A 1 181 ? 138.006 102.174 128.107 1.00 38.90  ? 181 LEU A CG  1 
ATOM   1281 C  CD1 . LEU A 1 181 ? 138.222 101.075 127.104 1.00 44.68  ? 181 LEU A CD1 1 
ATOM   1282 C  CD2 . LEU A 1 181 ? 136.679 102.002 128.802 1.00 43.17  ? 181 LEU A CD2 1 
ATOM   1283 N  N   . LEU A 1 182 ? 141.001 104.833 128.611 1.00 37.57  ? 182 LEU A N   1 
ATOM   1284 C  CA  . LEU A 1 182 ? 141.027 106.179 128.052 1.00 38.46  ? 182 LEU A CA  1 
ATOM   1285 C  C   . LEU A 1 182 ? 142.428 106.663 127.710 1.00 46.02  ? 182 LEU A C   1 
ATOM   1286 O  O   . LEU A 1 182 ? 142.603 107.376 126.720 1.00 46.09  ? 182 LEU A O   1 
ATOM   1287 C  CB  . LEU A 1 182 ? 140.373 107.160 129.025 1.00 35.16  ? 182 LEU A CB  1 
ATOM   1288 C  CG  . LEU A 1 182 ? 139.013 106.716 129.550 1.00 41.19  ? 182 LEU A CG  1 
ATOM   1289 C  CD1 . LEU A 1 182 ? 138.845 107.141 130.989 1.00 42.89  ? 182 LEU A CD1 1 
ATOM   1290 C  CD2 . LEU A 1 182 ? 137.915 107.293 128.688 1.00 34.06  ? 182 LEU A CD2 1 
ATOM   1291 N  N   . ILE A 1 183 ? 143.431 106.305 128.513 1.00 46.75  ? 183 ILE A N   1 
ATOM   1292 C  CA  . ILE A 1 183 ? 144.798 106.700 128.195 1.00 33.95  ? 183 ILE A CA  1 
ATOM   1293 C  C   . ILE A 1 183 ? 145.292 105.965 126.958 1.00 38.56  ? 183 ILE A C   1 
ATOM   1294 O  O   . ILE A 1 183 ? 146.015 106.533 126.133 1.00 47.47  ? 183 ILE A O   1 
ATOM   1295 C  CB  . ILE A 1 183 ? 145.726 106.460 129.396 1.00 33.45  ? 183 ILE A CB  1 
ATOM   1296 C  CG1 . ILE A 1 183 ? 145.046 106.881 130.694 1.00 32.23  ? 183 ILE A CG1 1 
ATOM   1297 C  CG2 . ILE A 1 183 ? 147.018 107.212 129.212 1.00 47.29  ? 183 ILE A CG2 1 
ATOM   1298 C  CD1 . ILE A 1 183 ? 144.880 108.352 130.840 1.00 33.15  ? 183 ILE A CD1 1 
ATOM   1299 N  N   . ARG A 1 184 ? 144.915 104.696 126.812 1.00 44.76  ? 184 ARG A N   1 
ATOM   1300 C  CA  . ARG A 1 184 ? 145.305 103.863 125.677 1.00 51.63  ? 184 ARG A CA  1 
ATOM   1301 C  C   . ARG A 1 184 ? 146.825 103.887 125.517 1.00 54.56  ? 184 ARG A C   1 
ATOM   1302 O  O   . ARG A 1 184 ? 147.379 104.399 124.544 1.00 53.67  ? 184 ARG A O   1 
ATOM   1303 C  CB  . ARG A 1 184 ? 144.572 104.313 124.406 1.00 54.82  ? 184 ARG A CB  1 
ATOM   1304 C  CG  . ARG A 1 184 ? 144.444 103.293 123.251 1.00 51.35  ? 184 ARG A CG  1 
ATOM   1305 C  CD  . ARG A 1 184 ? 145.744 102.977 122.525 1.00 55.23  ? 184 ARG A CD  1 
ATOM   1306 N  NE  . ARG A 1 184 ? 145.533 102.215 121.300 1.00 58.55  ? 184 ARG A NE  1 
ATOM   1307 C  CZ  . ARG A 1 184 ? 145.465 100.893 121.236 1.00 59.88  ? 184 ARG A CZ  1 
ATOM   1308 N  NH1 . ARG A 1 184 ? 145.588 100.141 122.315 1.00 57.67  ? 184 ARG A NH1 1 
ATOM   1309 N  NH2 . ARG A 1 184 ? 145.272 100.310 120.057 1.00 58.04  ? 184 ARG A NH2 1 
ATOM   1310 N  N   . SER A 1 185 ? 147.499 103.364 126.540 1.00 50.14  ? 185 SER A N   1 
ATOM   1311 C  CA  . SER A 1 185 ? 148.950 103.244 126.528 1.00 48.36  ? 185 SER A CA  1 
ATOM   1312 C  C   . SER A 1 185 ? 149.423 102.327 127.645 1.00 49.41  ? 185 SER A C   1 
ATOM   1313 O  O   . SER A 1 185 ? 149.022 102.490 128.800 1.00 53.91  ? 185 SER A O   1 
ATOM   1314 C  CB  . SER A 1 185 ? 149.609 104.615 126.665 1.00 48.90  ? 185 SER A CB  1 
ATOM   1315 O  OG  . SER A 1 185 ? 151.017 104.505 126.593 1.00 49.69  ? 185 SER A OG  1 
ATOM   1316 N  N   . TYR A 1 186 ? 150.265 101.351 127.308 1.00 59.53  ? 186 TYR A N   1 
ATOM   1317 C  CA  . TYR A 1 186 ? 150.917 100.554 128.339 1.00 58.46  ? 186 TYR A CA  1 
ATOM   1318 C  C   . TYR A 1 186 ? 151.997 101.359 129.045 1.00 55.72  ? 186 TYR A C   1 
ATOM   1319 O  O   . TYR A 1 186 ? 152.169 101.245 130.262 1.00 56.68  ? 186 TYR A O   1 
ATOM   1320 C  CB  . TYR A 1 186 ? 151.521 99.291  127.728 1.00 57.77  ? 186 TYR A CB  1 
ATOM   1321 C  CG  . TYR A 1 186 ? 150.535 98.183  127.460 1.00 53.44  ? 186 TYR A CG  1 
ATOM   1322 C  CD1 . TYR A 1 186 ? 150.043 97.401  128.489 1.00 56.20  ? 186 TYR A CD1 1 
ATOM   1323 C  CD2 . TYR A 1 186 ? 150.108 97.912  126.172 1.00 51.10  ? 186 TYR A CD2 1 
ATOM   1324 C  CE1 . TYR A 1 186 ? 149.148 96.385  128.244 1.00 56.86  ? 186 TYR A CE1 1 
ATOM   1325 C  CE2 . TYR A 1 186 ? 149.214 96.899  125.918 1.00 57.62  ? 186 TYR A CE2 1 
ATOM   1326 C  CZ  . TYR A 1 186 ? 148.737 96.138  126.957 1.00 58.45  ? 186 TYR A CZ  1 
ATOM   1327 O  OH  . TYR A 1 186 ? 147.844 95.127  126.705 1.00 59.70  ? 186 TYR A OH  1 
ATOM   1328 N  N   . GLY A 1 187 ? 152.734 102.178 128.296 1.00 52.56  ? 187 GLY A N   1 
ATOM   1329 C  CA  . GLY A 1 187 ? 153.844 102.905 128.887 1.00 53.10  ? 187 GLY A CA  1 
ATOM   1330 C  C   . GLY A 1 187 ? 153.403 103.886 129.954 1.00 53.94  ? 187 GLY A C   1 
ATOM   1331 O  O   . GLY A 1 187 ? 153.924 103.879 131.069 1.00 61.75  ? 187 GLY A O   1 
ATOM   1332 N  N   . LEU A 1 188 ? 152.420 104.732 129.632 1.00 51.08  ? 188 LEU A N   1 
ATOM   1333 C  CA  . LEU A 1 188 ? 151.945 105.724 130.593 1.00 49.83  ? 188 LEU A CA  1 
ATOM   1334 C  C   . LEU A 1 188 ? 151.372 105.051 131.832 1.00 52.61  ? 188 LEU A C   1 
ATOM   1335 O  O   . LEU A 1 188 ? 151.718 105.401 132.970 1.00 57.49  ? 188 LEU A O   1 
ATOM   1336 C  CB  . LEU A 1 188 ? 150.884 106.615 129.947 1.00 45.04  ? 188 LEU A CB  1 
ATOM   1337 C  CG  . LEU A 1 188 ? 151.208 107.498 128.741 1.00 49.80  ? 188 LEU A CG  1 
ATOM   1338 C  CD1 . LEU A 1 188 ? 150.280 108.696 128.723 1.00 48.96  ? 188 LEU A CD1 1 
ATOM   1339 C  CD2 . LEU A 1 188 ? 152.656 107.949 128.738 1.00 48.56  ? 188 LEU A CD2 1 
ATOM   1340 N  N   . CYS A 1 189 ? 150.489 104.075 131.623 1.00 42.98  ? 189 CYS A N   1 
ATOM   1341 C  CA  . CYS A 1 189 ? 149.799 103.442 132.737 1.00 39.24  ? 189 CYS A CA  1 
ATOM   1342 C  C   . CYS A 1 189 ? 150.767 102.682 133.627 1.00 45.17  ? 189 CYS A C   1 
ATOM   1343 O  O   . CYS A 1 189 ? 150.692 102.785 134.853 1.00 54.35  ? 189 CYS A O   1 
ATOM   1344 C  CB  . CYS A 1 189 ? 148.701 102.522 132.212 1.00 45.60  ? 189 CYS A CB  1 
ATOM   1345 S  SG  . CYS A 1 189 ? 147.361 103.390 131.372 1.00 54.57  ? 189 CYS A SG  1 
ATOM   1346 N  N   . TRP A 1 190 ? 151.697 101.932 133.037 1.00 50.45  ? 190 TRP A N   1 
ATOM   1347 C  CA  . TRP A 1 190 ? 152.644 101.183 133.854 1.00 49.06  ? 190 TRP A CA  1 
ATOM   1348 C  C   . TRP A 1 190 ? 153.628 102.110 134.550 1.00 46.35  ? 190 TRP A C   1 
ATOM   1349 O  O   . TRP A 1 190 ? 153.992 101.875 135.706 1.00 50.59  ? 190 TRP A O   1 
ATOM   1350 C  CB  . TRP A 1 190 ? 153.374 100.150 133.001 1.00 46.16  ? 190 TRP A CB  1 
ATOM   1351 C  CG  . TRP A 1 190 ? 152.671 98.841  132.974 1.00 43.80  ? 190 TRP A CG  1 
ATOM   1352 C  CD1 . TRP A 1 190 ? 151.801 98.402  132.028 1.00 46.56  ? 190 TRP A CD1 1 
ATOM   1353 C  CD2 . TRP A 1 190 ? 152.761 97.800  133.950 1.00 47.84  ? 190 TRP A CD2 1 
ATOM   1354 N  NE1 . TRP A 1 190 ? 151.346 97.149  132.346 1.00 49.56  ? 190 TRP A NE1 1 
ATOM   1355 C  CE2 . TRP A 1 190 ? 151.922 96.757  133.525 1.00 49.01  ? 190 TRP A CE2 1 
ATOM   1356 C  CE3 . TRP A 1 190 ? 153.474 97.647  135.141 1.00 51.85  ? 190 TRP A CE3 1 
ATOM   1357 C  CZ2 . TRP A 1 190 ? 151.775 95.578  134.246 1.00 49.24  ? 190 TRP A CZ2 1 
ATOM   1358 C  CZ3 . TRP A 1 190 ? 153.327 96.478  135.853 1.00 53.21  ? 190 TRP A CZ3 1 
ATOM   1359 C  CH2 . TRP A 1 190 ? 152.485 95.459  135.405 1.00 51.79  ? 190 TRP A CH2 1 
ATOM   1360 N  N   . THR A 1 191 ? 154.054 103.180 133.876 1.00 47.58  ? 191 THR A N   1 
ATOM   1361 C  CA  . THR A 1 191 ? 154.930 104.159 134.504 1.00 45.70  ? 191 THR A CA  1 
ATOM   1362 C  C   . THR A 1 191 ? 154.291 104.738 135.753 1.00 55.34  ? 191 THR A C   1 
ATOM   1363 O  O   . THR A 1 191 ? 154.901 104.757 136.828 1.00 59.78  ? 191 THR A O   1 
ATOM   1364 C  CB  . THR A 1 191 ? 155.243 105.276 133.515 1.00 50.83  ? 191 THR A CB  1 
ATOM   1365 O  OG1 . THR A 1 191 ? 155.875 104.722 132.357 1.00 62.36  ? 191 THR A OG1 1 
ATOM   1366 C  CG2 . THR A 1 191 ? 156.148 106.308 134.150 1.00 54.32  ? 191 THR A CG2 1 
ATOM   1367 N  N   . ILE A 1 192 ? 153.051 105.212 135.632 1.00 52.78  ? 192 ILE A N   1 
ATOM   1368 C  CA  . ILE A 1 192 ? 152.423 105.866 136.772 1.00 48.72  ? 192 ILE A CA  1 
ATOM   1369 C  C   . ILE A 1 192 ? 152.026 104.853 137.839 1.00 51.07  ? 192 ILE A C   1 
ATOM   1370 O  O   . ILE A 1 192 ? 152.135 105.132 139.037 1.00 55.74  ? 192 ILE A O   1 
ATOM   1371 C  CB  . ILE A 1 192 ? 151.251 106.743 136.310 1.00 37.90  ? 192 ILE A CB  1 
ATOM   1372 C  CG1 . ILE A 1 192 ? 151.829 108.081 135.868 1.00 37.82  ? 192 ILE A CG1 1 
ATOM   1373 C  CG2 . ILE A 1 192 ? 150.238 106.926 137.416 1.00 41.65  ? 192 ILE A CG2 1 
ATOM   1374 C  CD1 . ILE A 1 192 ? 150.858 108.999 135.283 1.00 46.35  ? 192 ILE A CD1 1 
ATOM   1375 N  N   . SER A 1 193 ? 151.607 103.652 137.437 1.00 45.15  ? 193 SER A N   1 
ATOM   1376 C  CA  . SER A 1 193 ? 151.335 102.609 138.417 1.00 41.18  ? 193 SER A CA  1 
ATOM   1377 C  C   . SER A 1 193 ? 152.572 102.307 139.250 1.00 46.25  ? 193 SER A C   1 
ATOM   1378 O  O   . SER A 1 193 ? 152.515 102.294 140.484 1.00 56.49  ? 193 SER A O   1 
ATOM   1379 C  CB  . SER A 1 193 ? 150.845 101.348 137.709 1.00 49.44  ? 193 SER A CB  1 
ATOM   1380 O  OG  . SER A 1 193 ? 150.964 100.214 138.545 1.00 56.41  ? 193 SER A OG  1 
ATOM   1381 N  N   . ILE A 1 194 ? 153.709 102.088 138.589 1.00 41.14  ? 194 ILE A N   1 
ATOM   1382 C  CA  . ILE A 1 194 ? 154.933 101.740 139.302 1.00 43.59  ? 194 ILE A CA  1 
ATOM   1383 C  C   . ILE A 1 194 ? 155.379 102.892 140.191 1.00 47.90  ? 194 ILE A C   1 
ATOM   1384 O  O   . ILE A 1 194 ? 155.730 102.694 141.361 1.00 57.45  ? 194 ILE A O   1 
ATOM   1385 C  CB  . ILE A 1 194 ? 156.030 101.331 138.303 1.00 48.94  ? 194 ILE A CB  1 
ATOM   1386 C  CG1 . ILE A 1 194 ? 155.958 99.829  138.024 1.00 53.63  ? 194 ILE A CG1 1 
ATOM   1387 C  CG2 . ILE A 1 194 ? 157.408 101.709 138.821 1.00 49.27  ? 194 ILE A CG2 1 
ATOM   1388 C  CD1 . ILE A 1 194 ? 156.661 99.411  136.755 1.00 52.65  ? 194 ILE A CD1 1 
ATOM   1389 N  N   . THR A 1 195 ? 155.364 104.118 139.657 1.00 46.08  ? 195 THR A N   1 
ATOM   1390 C  CA  . THR A 1 195 ? 155.825 105.258 140.442 1.00 48.23  ? 195 THR A CA  1 
ATOM   1391 C  C   . THR A 1 195 ? 154.945 105.479 141.663 1.00 49.64  ? 195 THR A C   1 
ATOM   1392 O  O   . THR A 1 195 ? 155.451 105.736 142.760 1.00 49.98  ? 195 THR A O   1 
ATOM   1393 C  CB  . THR A 1 195 ? 155.868 106.522 139.585 1.00 49.63  ? 195 THR A CB  1 
ATOM   1394 O  OG1 . THR A 1 195 ? 154.728 106.555 138.724 1.00 47.09  ? 195 THR A OG1 1 
ATOM   1395 C  CG2 . THR A 1 195 ? 157.130 106.555 138.743 1.00 54.57  ? 195 THR A CG2 1 
ATOM   1396 N  N   . TRP A 1 196 ? 153.624 105.372 141.503 1.00 51.23  ? 196 TRP A N   1 
ATOM   1397 C  CA  . TRP A 1 196 ? 152.743 105.598 142.641 1.00 46.12  ? 196 TRP A CA  1 
ATOM   1398 C  C   . TRP A 1 196 ? 152.857 104.484 143.670 1.00 51.81  ? 196 TRP A C   1 
ATOM   1399 O  O   . TRP A 1 196 ? 152.792 104.746 144.874 1.00 56.89  ? 196 TRP A O   1 
ATOM   1400 C  CB  . TRP A 1 196 ? 151.295 105.744 142.191 1.00 47.85  ? 196 TRP A CB  1 
ATOM   1401 C  CG  . TRP A 1 196 ? 150.365 105.700 143.351 1.00 48.93  ? 196 TRP A CG  1 
ATOM   1402 C  CD1 . TRP A 1 196 ? 149.363 104.809 143.560 1.00 53.17  ? 196 TRP A CD1 1 
ATOM   1403 C  CD2 . TRP A 1 196 ? 150.370 106.574 144.487 1.00 50.43  ? 196 TRP A CD2 1 
ATOM   1404 N  NE1 . TRP A 1 196 ? 148.733 105.076 144.748 1.00 53.96  ? 196 TRP A NE1 1 
ATOM   1405 C  CE2 . TRP A 1 196 ? 149.335 106.156 145.336 1.00 51.56  ? 196 TRP A CE2 1 
ATOM   1406 C  CE3 . TRP A 1 196 ? 151.145 107.674 144.862 1.00 52.95  ? 196 TRP A CE3 1 
ATOM   1407 C  CZ2 . TRP A 1 196 ? 149.053 106.798 146.534 1.00 53.14  ? 196 TRP A CZ2 1 
ATOM   1408 C  CZ3 . TRP A 1 196 ? 150.865 108.305 146.051 1.00 48.49  ? 196 TRP A CZ3 1 
ATOM   1409 C  CH2 . TRP A 1 196 ? 149.830 107.866 146.873 1.00 50.56  ? 196 TRP A CH2 1 
ATOM   1410 N  N   . GLU A 1 197 ? 152.995 103.231 143.232 1.00 56.26  ? 197 GLU A N   1 
ATOM   1411 C  CA  . GLU A 1 197 ? 153.163 102.158 144.204 1.00 56.86  ? 197 GLU A CA  1 
ATOM   1412 C  C   . GLU A 1 197 ? 154.462 102.325 144.980 1.00 61.29  ? 197 GLU A C   1 
ATOM   1413 O  O   . GLU A 1 197 ? 154.498 102.116 146.197 1.00 64.84  ? 197 GLU A O   1 
ATOM   1414 C  CB  . GLU A 1 197 ? 153.111 100.799 143.514 1.00 55.44  ? 197 GLU A CB  1 
ATOM   1415 C  CG  . GLU A 1 197 ? 151.770 100.477 142.885 1.00 57.32  ? 197 GLU A CG  1 
ATOM   1416 C  CD  . GLU A 1 197 ? 150.599 101.043 143.657 1.00 60.63  ? 197 GLU A CD  1 
ATOM   1417 O  OE1 . GLU A 1 197 ? 150.446 100.705 144.848 1.00 64.90  ? 197 GLU A OE1 1 
ATOM   1418 O  OE2 . GLU A 1 197 ? 149.821 101.819 143.067 1.00 59.97  ? 197 GLU A OE2 1 
ATOM   1419 N  N   . LEU A 1 198 ? 155.538 102.721 144.297 1.00 52.67  ? 198 LEU A N   1 
ATOM   1420 C  CA  . LEU A 1 198 ? 156.783 103.013 144.998 1.00 48.39  ? 198 LEU A CA  1 
ATOM   1421 C  C   . LEU A 1 198 ? 156.603 104.164 145.979 1.00 55.10  ? 198 LEU A C   1 
ATOM   1422 O  O   . LEU A 1 198 ? 157.113 104.117 147.105 1.00 60.92  ? 198 LEU A O   1 
ATOM   1423 C  CB  . LEU A 1 198 ? 157.881 103.339 143.989 1.00 50.57  ? 198 LEU A CB  1 
ATOM   1424 C  CG  . LEU A 1 198 ? 158.857 102.229 143.610 1.00 55.58  ? 198 LEU A CG  1 
ATOM   1425 C  CD1 . LEU A 1 198 ? 158.129 100.928 143.326 1.00 54.60  ? 198 LEU A CD1 1 
ATOM   1426 C  CD2 . LEU A 1 198 ? 159.676 102.656 142.408 1.00 54.70  ? 198 LEU A CD2 1 
ATOM   1427 N  N   . THR A 1 199 ? 155.879 105.209 145.569 1.00 57.66  ? 199 THR A N   1 
ATOM   1428 C  CA  . THR A 1 199 ? 155.676 106.363 146.439 1.00 55.45  ? 199 THR A CA  1 
ATOM   1429 C  C   . THR A 1 199 ? 154.866 105.992 147.673 1.00 58.83  ? 199 THR A C   1 
ATOM   1430 O  O   . THR A 1 199 ? 155.167 106.453 148.776 1.00 61.21  ? 199 THR A O   1 
ATOM   1431 C  CB  . THR A 1 199 ? 154.995 107.490 145.664 1.00 53.74  ? 199 THR A CB  1 
ATOM   1432 O  OG1 . THR A 1 199 ? 155.976 108.209 144.909 1.00 59.14  ? 199 THR A OG1 1 
ATOM   1433 C  CG2 . THR A 1 199 ? 154.305 108.454 146.606 1.00 55.22  ? 199 THR A CG2 1 
ATOM   1434 N  N   . GLU A 1 200 ? 153.837 105.161 147.510 1.00 65.99  ? 200 GLU A N   1 
ATOM   1435 C  CA  . GLU A 1 200 ? 153.043 104.742 148.659 1.00 64.28  ? 200 GLU A CA  1 
ATOM   1436 C  C   . GLU A 1 200 ? 153.814 103.785 149.556 1.00 70.75  ? 200 GLU A C   1 
ATOM   1437 O  O   . GLU A 1 200 ? 153.614 103.788 150.775 1.00 71.46  ? 200 GLU A O   1 
ATOM   1438 C  CB  . GLU A 1 200 ? 151.737 104.102 148.200 1.00 60.57  ? 200 GLU A CB  1 
ATOM   1439 C  CG  . GLU A 1 200 ? 150.529 104.651 148.925 1.00 66.93  ? 200 GLU A CG  1 
ATOM   1440 C  CD  . GLU A 1 200 ? 149.226 104.055 148.441 1.00 72.07  ? 200 GLU A CD  1 
ATOM   1441 O  OE1 . GLU A 1 200 ? 149.264 103.134 147.601 1.00 73.69  ? 200 GLU A OE1 1 
ATOM   1442 O  OE2 . GLU A 1 200 ? 148.160 104.515 148.900 1.00 70.63  ? 200 GLU A OE2 1 
ATOM   1443 N  N   . LEU A 1 201 ? 154.685 102.953 148.980 1.00 71.98  ? 201 LEU A N   1 
ATOM   1444 C  CA  . LEU A 1 201 ? 155.561 102.124 149.800 1.00 69.16  ? 201 LEU A CA  1 
ATOM   1445 C  C   . LEU A 1 201 ? 156.510 102.983 150.626 1.00 68.54  ? 201 LEU A C   1 
ATOM   1446 O  O   . LEU A 1 201 ? 156.773 102.686 151.796 1.00 68.84  ? 201 LEU A O   1 
ATOM   1447 C  CB  . LEU A 1 201 ? 156.344 101.159 148.913 1.00 70.21  ? 201 LEU A CB  1 
ATOM   1448 C  CG  . LEU A 1 201 ? 157.451 100.356 149.592 1.00 73.26  ? 201 LEU A CG  1 
ATOM   1449 C  CD1 . LEU A 1 201 ? 156.887 99.521  150.732 1.00 69.85  ? 201 LEU A CD1 1 
ATOM   1450 C  CD2 . LEU A 1 201 ? 158.176 99.482  148.583 1.00 72.14  ? 201 LEU A CD2 1 
ATOM   1451 N  N   . PHE A 1 202 ? 157.041 104.049 150.028 1.00 63.50  ? 202 PHE A N   1 
ATOM   1452 C  CA  . PHE A 1 202 ? 157.928 104.947 150.760 1.00 63.23  ? 202 PHE A CA  1 
ATOM   1453 C  C   . PHE A 1 202 ? 157.170 105.720 151.834 1.00 70.32  ? 202 PHE A C   1 
ATOM   1454 O  O   . PHE A 1 202 ? 157.627 105.824 152.977 1.00 74.09  ? 202 PHE A O   1 
ATOM   1455 C  CB  . PHE A 1 202 ? 158.608 105.906 149.788 1.00 62.63  ? 202 PHE A CB  1 
ATOM   1456 C  CG  . PHE A 1 202 ? 159.283 107.067 150.451 1.00 65.86  ? 202 PHE A CG  1 
ATOM   1457 C  CD1 . PHE A 1 202 ? 160.419 106.880 151.215 1.00 65.96  ? 202 PHE A CD1 1 
ATOM   1458 C  CD2 . PHE A 1 202 ? 158.787 108.347 150.304 1.00 67.28  ? 202 PHE A CD2 1 
ATOM   1459 C  CE1 . PHE A 1 202 ? 161.044 107.946 151.820 1.00 68.53  ? 202 PHE A CE1 1 
ATOM   1460 C  CE2 . PHE A 1 202 ? 159.406 109.416 150.908 1.00 68.11  ? 202 PHE A CE2 1 
ATOM   1461 C  CZ  . PHE A 1 202 ? 160.537 109.215 151.667 1.00 70.36  ? 202 PHE A CZ  1 
ATOM   1462 N  N   . PHE A 1 203 ? 156.006 106.267 151.483 1.00 68.25  ? 203 PHE A N   1 
ATOM   1463 C  CA  . PHE A 1 203 ? 155.252 107.113 152.401 1.00 65.67  ? 203 PHE A CA  1 
ATOM   1464 C  C   . PHE A 1 203 ? 154.695 106.336 153.579 1.00 66.90  ? 203 PHE A C   1 
ATOM   1465 O  O   . PHE A 1 203 ? 154.283 106.949 154.567 1.00 74.11  ? 203 PHE A O   1 
ATOM   1466 C  CB  . PHE A 1 203 ? 154.111 107.811 151.662 1.00 63.31  ? 203 PHE A CB  1 
ATOM   1467 C  CG  . PHE A 1 203 ? 154.516 109.091 151.002 1.00 64.24  ? 203 PHE A CG  1 
ATOM   1468 C  CD1 . PHE A 1 203 ? 155.745 109.660 151.269 1.00 63.63  ? 203 PHE A CD1 1 
ATOM   1469 C  CD2 . PHE A 1 203 ? 153.674 109.720 150.111 1.00 63.53  ? 203 PHE A CD2 1 
ATOM   1470 C  CE1 . PHE A 1 203 ? 156.124 110.831 150.663 1.00 61.74  ? 203 PHE A CE1 1 
ATOM   1471 C  CE2 . PHE A 1 203 ? 154.048 110.894 149.503 1.00 63.80  ? 203 PHE A CE2 1 
ATOM   1472 C  CZ  . PHE A 1 203 ? 155.275 111.450 149.780 1.00 64.65  ? 203 PHE A CZ  1 
ATOM   1473 N  N   . MET A 1 204 ? 154.666 105.013 153.501 1.00 77.96  ? 204 MET A N   1 
ATOM   1474 C  CA  . MET A 1 204 ? 154.269 104.200 154.638 1.00 80.55  ? 204 MET A CA  1 
ATOM   1475 C  C   . MET A 1 204 ? 155.364 104.101 155.690 1.00 81.99  ? 204 MET A C   1 
ATOM   1476 O  O   . MET A 1 204 ? 155.221 103.333 156.646 1.00 83.13  ? 204 MET A O   1 
ATOM   1477 C  CB  . MET A 1 204 ? 153.852 102.806 154.166 1.00 81.85  ? 204 MET A CB  1 
ATOM   1478 C  CG  . MET A 1 204 ? 152.350 102.651 153.990 1.00 82.55  ? 204 MET A CG  1 
ATOM   1479 S  SD  . MET A 1 204 ? 151.893 101.385 152.792 1.00 93.23  ? 204 MET A SD  1 
ATOM   1480 C  CE  . MET A 1 204 ? 150.573 102.218 151.915 1.00 83.19  ? 204 MET A CE  1 
ATOM   1481 N  N   . HIS A 1 205 ? 156.458 104.850 155.524 1.00 82.67  ? 205 HIS A N   1 
ATOM   1482 C  CA  . HIS A 1 205 ? 157.440 104.982 156.592 1.00 85.77  ? 205 HIS A CA  1 
ATOM   1483 C  C   . HIS A 1 205 ? 156.889 105.792 157.757 1.00 88.45  ? 205 HIS A C   1 
ATOM   1484 O  O   . HIS A 1 205 ? 157.232 105.525 158.914 1.00 88.42  ? 205 HIS A O   1 
ATOM   1485 C  CB  . HIS A 1 205 ? 158.716 105.632 156.058 1.00 85.72  ? 205 HIS A CB  1 
ATOM   1486 C  CG  . HIS A 1 205 ? 158.665 107.128 156.023 1.00 86.32  ? 205 HIS A CG  1 
ATOM   1487 N  ND1 . HIS A 1 205 ? 157.862 107.825 155.146 1.00 83.98  ? 205 HIS A ND1 1 
ATOM   1488 C  CD2 . HIS A 1 205 ? 159.312 108.061 156.761 1.00 85.97  ? 205 HIS A CD2 1 
ATOM   1489 C  CE1 . HIS A 1 205 ? 158.021 109.122 155.342 1.00 83.69  ? 205 HIS A CE1 1 
ATOM   1490 N  NE2 . HIS A 1 205 ? 158.895 109.292 156.317 1.00 84.11  ? 205 HIS A NE2 1 
ATOM   1491 N  N   . LEU A 1 206 ? 156.039 106.784 157.477 1.00 86.24  ? 206 LEU A N   1 
ATOM   1492 C  CA  . LEU A 1 206 ? 155.447 107.569 158.553 1.00 85.47  ? 206 LEU A CA  1 
ATOM   1493 C  C   . LEU A 1 206 ? 154.358 106.794 159.281 1.00 88.78  ? 206 LEU A C   1 
ATOM   1494 O  O   . LEU A 1 206 ? 154.139 107.016 160.477 1.00 87.59  ? 206 LEU A O   1 
ATOM   1495 C  CB  . LEU A 1 206 ? 154.888 108.884 158.003 1.00 86.53  ? 206 LEU A CB  1 
ATOM   1496 C  CG  . LEU A 1 206 ? 153.647 108.857 157.102 1.00 84.73  ? 206 LEU A CG  1 
ATOM   1497 C  CD1 . LEU A 1 206 ? 152.359 109.036 157.890 1.00 85.85  ? 206 LEU A CD1 1 
ATOM   1498 C  CD2 . LEU A 1 206 ? 153.760 109.928 156.029 1.00 85.42  ? 206 LEU A CD2 1 
ATOM   1499 N  N   . LEU A 1 207 ? 153.678 105.890 158.591 1.00 104.81 ? 207 LEU A N   1 
ATOM   1500 C  CA  . LEU A 1 207 ? 152.498 105.227 159.131 1.00 105.67 ? 207 LEU A CA  1 
ATOM   1501 C  C   . LEU A 1 207 ? 152.927 104.163 160.134 1.00 106.40 ? 207 LEU A C   1 
ATOM   1502 O  O   . LEU A 1 207 ? 153.476 103.132 159.723 1.00 102.44 ? 207 LEU A O   1 
ATOM   1503 C  CB  . LEU A 1 207 ? 151.691 104.598 157.996 1.00 104.04 ? 207 LEU A CB  1 
ATOM   1504 C  CG  . LEU A 1 207 ? 150.190 104.341 158.179 1.00 105.66 ? 207 LEU A CG  1 
ATOM   1505 C  CD1 . LEU A 1 207 ? 149.577 103.846 156.868 1.00 104.37 ? 207 LEU A CD1 1 
ATOM   1506 C  CD2 . LEU A 1 207 ? 149.845 103.421 159.340 1.00 104.98 ? 207 LEU A CD2 1 
ATOM   1507 N  N   . PRO A 1 208 ? 152.700 104.355 161.433 1.00 120.97 ? 208 PRO A N   1 
ATOM   1508 C  CA  . PRO A 1 208 ? 153.223 103.401 162.421 1.00 121.09 ? 208 PRO A CA  1 
ATOM   1509 C  C   . PRO A 1 208 ? 152.436 102.102 162.531 1.00 120.87 ? 208 PRO A C   1 
ATOM   1510 O  O   . PRO A 1 208 ? 153.031 101.020 162.564 1.00 120.37 ? 208 PRO A O   1 
ATOM   1511 C  CB  . PRO A 1 208 ? 153.163 104.198 163.729 1.00 119.62 ? 208 PRO A CB  1 
ATOM   1512 C  CG  . PRO A 1 208 ? 152.029 105.150 163.535 1.00 118.76 ? 208 PRO A CG  1 
ATOM   1513 C  CD  . PRO A 1 208 ? 151.945 105.455 162.060 1.00 118.49 ? 208 PRO A CD  1 
ATOM   1514 N  N   . ASN A 1 209 ? 151.104 102.185 162.582 1.00 128.81 ? 209 ASN A N   1 
ATOM   1515 C  CA  . ASN A 1 209 ? 150.311 101.026 162.982 1.00 128.61 ? 209 ASN A CA  1 
ATOM   1516 C  C   . ASN A 1 209 ? 150.192 99.978  161.882 1.00 129.57 ? 209 ASN A C   1 
ATOM   1517 O  O   . ASN A 1 209 ? 150.210 98.778  162.180 1.00 127.97 ? 209 ASN A O   1 
ATOM   1518 C  CB  . ASN A 1 209 ? 148.918 101.469 163.438 1.00 127.52 ? 209 ASN A CB  1 
ATOM   1519 C  CG  . ASN A 1 209 ? 148.283 102.465 162.492 1.00 128.39 ? 209 ASN A CG  1 
ATOM   1520 O  OD1 . ASN A 1 209 ? 148.677 103.630 162.443 1.00 128.63 ? 209 ASN A OD1 1 
ATOM   1521 N  ND2 . ASN A 1 209 ? 147.286 102.014 161.741 1.00 128.36 ? 209 ASN A ND2 1 
ATOM   1522 N  N   . PHE A 1 210 ? 150.063 100.395 160.625 1.00 127.96 ? 210 PHE A N   1 
ATOM   1523 C  CA  . PHE A 1 210 ? 149.869 99.441  159.540 1.00 126.28 ? 210 PHE A CA  1 
ATOM   1524 C  C   . PHE A 1 210 ? 151.116 98.585  159.359 1.00 126.16 ? 210 PHE A C   1 
ATOM   1525 O  O   . PHE A 1 210 ? 152.241 99.095  159.371 1.00 126.92 ? 210 PHE A O   1 
ATOM   1526 C  CB  . PHE A 1 210 ? 149.537 100.169 158.238 1.00 125.62 ? 210 PHE A CB  1 
ATOM   1527 C  CG  . PHE A 1 210 ? 148.068 100.212 157.922 1.00 126.82 ? 210 PHE A CG  1 
ATOM   1528 C  CD1 . PHE A 1 210 ? 147.179 100.837 158.782 1.00 126.03 ? 210 PHE A CD1 1 
ATOM   1529 C  CD2 . PHE A 1 210 ? 147.575 99.634  156.765 1.00 126.48 ? 210 PHE A CD2 1 
ATOM   1530 C  CE1 . PHE A 1 210 ? 145.826 100.882 158.493 1.00 126.05 ? 210 PHE A CE1 1 
ATOM   1531 C  CE2 . PHE A 1 210 ? 146.224 99.674  156.471 1.00 125.24 ? 210 PHE A CE2 1 
ATOM   1532 C  CZ  . PHE A 1 210 ? 145.349 100.299 157.336 1.00 125.90 ? 210 PHE A CZ  1 
ATOM   1533 N  N   . ALA A 1 211 ? 150.913 97.278  159.195 1.00 124.45 ? 211 ALA A N   1 
ATOM   1534 C  CA  . ALA A 1 211 ? 151.999 96.333  158.979 1.00 124.57 ? 211 ALA A CA  1 
ATOM   1535 C  C   . ALA A 1 211 ? 152.031 95.810  157.547 1.00 125.06 ? 211 ALA A C   1 
ATOM   1536 O  O   . ALA A 1 211 ? 152.495 94.690  157.311 1.00 123.90 ? 211 ALA A O   1 
ATOM   1537 C  CB  . ALA A 1 211 ? 151.897 95.170  159.966 1.00 123.57 ? 211 ALA A CB  1 
ATOM   1538 N  N   . GLU A 1 212 ? 151.543 96.596  156.588 1.00 124.49 ? 212 GLU A N   1 
ATOM   1539 C  CA  . GLU A 1 212 ? 151.515 96.164  155.196 1.00 124.44 ? 212 GLU A CA  1 
ATOM   1540 C  C   . GLU A 1 212 ? 152.926 95.994  154.654 1.00 124.67 ? 212 GLU A C   1 
ATOM   1541 O  O   . GLU A 1 212 ? 153.637 96.978  154.427 1.00 124.82 ? 212 GLU A O   1 
ATOM   1542 C  CB  . GLU A 1 212 ? 150.734 97.159  154.336 1.00 123.31 ? 212 GLU A CB  1 
ATOM   1543 C  CG  . GLU A 1 212 ? 149.295 97.356  154.768 1.00 123.35 ? 212 GLU A CG  1 
ATOM   1544 C  CD  . GLU A 1 212 ? 148.410 97.819  153.630 1.00 123.75 ? 212 GLU A CD  1 
ATOM   1545 O  OE1 . GLU A 1 212 ? 148.694 98.891  153.056 1.00 122.25 ? 212 GLU A OE1 1 
ATOM   1546 O  OE2 . GLU A 1 212 ? 147.432 97.112  153.307 1.00 124.31 ? 212 GLU A OE2 1 
ATOM   1547 N  N   . CYS A 1 213 ? 153.333 94.746  154.438 1.00 119.71 ? 213 CYS A N   1 
ATOM   1548 C  CA  . CYS A 1 213 ? 154.672 94.463  153.955 1.00 120.17 ? 213 CYS A CA  1 
ATOM   1549 C  C   . CYS A 1 213 ? 154.834 94.965  152.521 1.00 118.86 ? 213 CYS A C   1 
ATOM   1550 O  O   . CYS A 1 213 ? 153.865 95.305  151.836 1.00 117.37 ? 213 CYS A O   1 
ATOM   1551 C  CB  . CYS A 1 213 ? 154.963 92.966  154.040 1.00 119.27 ? 213 CYS A CB  1 
ATOM   1552 S  SG  . CYS A 1 213 ? 156.648 92.503  153.585 1.00 119.26 ? 213 CYS A SG  1 
ATOM   1553 N  N   . TRP A 1 214 ? 156.090 95.017  152.071 1.00 116.45 ? 214 TRP A N   1 
ATOM   1554 C  CA  . TRP A 1 214 ? 156.374 95.571  150.752 1.00 116.38 ? 214 TRP A CA  1 
ATOM   1555 C  C   . TRP A 1 214 ? 155.717 94.760  149.647 1.00 115.51 ? 214 TRP A C   1 
ATOM   1556 O  O   . TRP A 1 214 ? 155.388 95.310  148.588 1.00 114.25 ? 214 TRP A O   1 
ATOM   1557 C  CB  . TRP A 1 214 ? 157.884 95.650  150.522 1.00 117.04 ? 214 TRP A CB  1 
ATOM   1558 C  CG  . TRP A 1 214 ? 158.612 94.378  150.831 1.00 117.55 ? 214 TRP A CG  1 
ATOM   1559 C  CD1 . TRP A 1 214 ? 159.202 94.038  152.013 1.00 116.50 ? 214 TRP A CD1 1 
ATOM   1560 C  CD2 . TRP A 1 214 ? 158.828 93.275  149.943 1.00 117.66 ? 214 TRP A CD2 1 
ATOM   1561 N  NE1 . TRP A 1 214 ? 159.772 92.792  151.917 1.00 117.03 ? 214 TRP A NE1 1 
ATOM   1562 C  CE2 . TRP A 1 214 ? 159.556 92.302  150.656 1.00 118.04 ? 214 TRP A CE2 1 
ATOM   1563 C  CE3 . TRP A 1 214 ? 158.477 93.016  148.616 1.00 116.64 ? 214 TRP A CE3 1 
ATOM   1564 C  CZ2 . TRP A 1 214 ? 159.939 91.090  150.085 1.00 116.43 ? 214 TRP A CZ2 1 
ATOM   1565 C  CZ3 . TRP A 1 214 ? 158.858 91.813  148.052 1.00 116.76 ? 214 TRP A CZ3 1 
ATOM   1566 C  CH2 . TRP A 1 214 ? 159.582 90.865  148.785 1.00 115.60 ? 214 TRP A CH2 1 
ATOM   1567 N  N   . TRP A 1 215 ? 155.509 93.459  149.870 1.00 114.78 ? 215 TRP A N   1 
ATOM   1568 C  CA  . TRP A 1 215 ? 154.893 92.637  148.836 1.00 115.76 ? 215 TRP A CA  1 
ATOM   1569 C  C   . TRP A 1 215 ? 153.496 93.131  148.495 1.00 115.92 ? 215 TRP A C   1 
ATOM   1570 O  O   . TRP A 1 215 ? 153.114 93.116  147.322 1.00 115.18 ? 215 TRP A O   1 
ATOM   1571 C  CB  . TRP A 1 215 ? 154.867 91.165  149.261 1.00 115.84 ? 215 TRP A CB  1 
ATOM   1572 C  CG  . TRP A 1 215 ? 153.900 90.829  150.360 1.00 116.15 ? 215 TRP A CG  1 
ATOM   1573 C  CD1 . TRP A 1 215 ? 154.190 90.676  151.683 1.00 116.76 ? 215 TRP A CD1 1 
ATOM   1574 C  CD2 . TRP A 1 215 ? 152.494 90.576  150.227 1.00 116.26 ? 215 TRP A CD2 1 
ATOM   1575 N  NE1 . TRP A 1 215 ? 153.053 90.360  152.386 1.00 116.78 ? 215 TRP A NE1 1 
ATOM   1576 C  CE2 . TRP A 1 215 ? 151.998 90.292  151.515 1.00 116.75 ? 215 TRP A CE2 1 
ATOM   1577 C  CE3 . TRP A 1 215 ? 151.607 90.570  149.147 1.00 115.47 ? 215 TRP A CE3 1 
ATOM   1578 C  CZ2 . TRP A 1 215 ? 150.656 90.005  151.750 1.00 116.70 ? 215 TRP A CZ2 1 
ATOM   1579 C  CZ3 . TRP A 1 215 ? 150.275 90.289  149.384 1.00 116.57 ? 215 TRP A CZ3 1 
ATOM   1580 C  CH2 . TRP A 1 215 ? 149.813 90.008  150.674 1.00 117.17 ? 215 TRP A CH2 1 
ATOM   1581 N  N   . ASP A 1 216 ? 152.752 93.627  149.489 1.00 110.61 ? 216 ASP A N   1 
ATOM   1582 C  CA  . ASP A 1 216 ? 151.373 94.051  149.262 1.00 109.56 ? 216 ASP A CA  1 
ATOM   1583 C  C   . ASP A 1 216 ? 151.276 95.097  148.159 1.00 109.07 ? 216 ASP A C   1 
ATOM   1584 O  O   . ASP A 1 216 ? 150.346 95.063  147.345 1.00 108.75 ? 216 ASP A O   1 
ATOM   1585 C  CB  . ASP A 1 216 ? 150.773 94.595  150.557 1.00 110.46 ? 216 ASP A CB  1 
ATOM   1586 C  CG  . ASP A 1 216 ? 149.355 95.103  150.375 1.00 110.78 ? 216 ASP A CG  1 
ATOM   1587 O  OD1 . ASP A 1 216 ? 148.623 94.544  149.533 1.00 109.17 ? 216 ASP A OD1 1 
ATOM   1588 O  OD2 . ASP A 1 216 ? 148.974 96.067  151.071 1.00 111.58 ? 216 ASP A OD2 1 
ATOM   1589 N  N   . GLN A 1 217 ? 152.221 96.036  148.110 1.00 95.47  ? 217 GLN A N   1 
ATOM   1590 C  CA  . GLN A 1 217 ? 152.178 97.106  147.121 1.00 95.72  ? 217 GLN A CA  1 
ATOM   1591 C  C   . GLN A 1 217 ? 153.353 97.053  146.152 1.00 95.03  ? 217 GLN A C   1 
ATOM   1592 O  O   . GLN A 1 217 ? 153.653 98.054  145.496 1.00 92.77  ? 217 GLN A O   1 
ATOM   1593 C  CB  . GLN A 1 217 ? 152.113 98.472  147.806 1.00 93.73  ? 217 GLN A CB  1 
ATOM   1594 C  CG  . GLN A 1 217 ? 150.933 98.623  148.749 1.00 94.72  ? 217 GLN A CG  1 
ATOM   1595 C  CD  . GLN A 1 217 ? 150.206 99.931  148.550 1.00 94.20  ? 217 GLN A CD  1 
ATOM   1596 O  OE1 . GLN A 1 217 ? 150.582 100.734 147.700 1.00 90.31  ? 217 GLN A OE1 1 
ATOM   1597 N  NE2 . GLN A 1 217 ? 149.152 100.149 149.327 1.00 94.17  ? 217 GLN A NE2 1 
ATOM   1598 N  N   . VAL A 1 218 ? 154.031 95.914  146.055 1.00 100.46 ? 218 VAL A N   1 
ATOM   1599 C  CA  . VAL A 1 218 ? 155.014 95.704  145.000 1.00 100.98 ? 218 VAL A CA  1 
ATOM   1600 C  C   . VAL A 1 218 ? 154.690 94.503  144.117 1.00 98.71  ? 218 VAL A C   1 
ATOM   1601 O  O   . VAL A 1 218 ? 155.089 94.488  142.940 1.00 99.76  ? 218 VAL A O   1 
ATOM   1602 C  CB  . VAL A 1 218 ? 156.438 95.581  145.589 1.00 100.65 ? 218 VAL A CB  1 
ATOM   1603 C  CG1 . VAL A 1 218 ? 157.474 95.298  144.511 1.00 98.97  ? 218 VAL A CG1 1 
ATOM   1604 C  CG2 . VAL A 1 218 ? 156.808 96.862  146.314 1.00 99.15  ? 218 VAL A CG2 1 
ATOM   1605 N  N   . ILE A 1 219 ? 153.938 93.516  144.599 1.00 95.48  ? 219 ILE A N   1 
ATOM   1606 C  CA  . ILE A 1 219 ? 153.608 92.344  143.803 1.00 98.24  ? 219 ILE A CA  1 
ATOM   1607 C  C   . ILE A 1 219 ? 152.102 92.308  143.588 1.00 98.76  ? 219 ILE A C   1 
ATOM   1608 O  O   . ILE A 1 219 ? 151.628 92.372  142.448 1.00 98.61  ? 219 ILE A O   1 
ATOM   1609 C  CB  . ILE A 1 219 ? 154.111 91.058  144.484 1.00 98.99  ? 219 ILE A CB  1 
ATOM   1610 C  CG1 . ILE A 1 219 ? 155.556 91.242  144.954 1.00 97.57  ? 219 ILE A CG1 1 
ATOM   1611 C  CG2 . ILE A 1 219 ? 153.998 89.869  143.542 1.00 95.94  ? 219 ILE A CG2 1 
ATOM   1612 C  CD1 . ILE A 1 219 ? 156.169 90.001  145.556 1.00 98.89  ? 219 ILE A CD1 1 
ATOM   1613 N  N   . LEU A 1 220 ? 151.344 92.244  144.685 1.00 97.30  ? 220 LEU A N   1 
ATOM   1614 C  CA  . LEU A 1 220 ? 149.890 92.146  144.584 1.00 96.66  ? 220 LEU A CA  1 
ATOM   1615 C  C   . LEU A 1 220 ? 149.298 93.358  143.878 1.00 96.62  ? 220 LEU A C   1 
ATOM   1616 O  O   . LEU A 1 220 ? 148.374 93.224  143.069 1.00 96.76  ? 220 LEU A O   1 
ATOM   1617 C  CB  . LEU A 1 220 ? 149.279 91.982  145.978 1.00 98.63  ? 220 LEU A CB  1 
ATOM   1618 C  CG  . LEU A 1 220 ? 147.757 92.072  146.138 1.00 99.21  ? 220 LEU A CG  1 
ATOM   1619 C  CD1 . LEU A 1 220 ? 147.269 91.036  147.135 1.00 98.80  ? 220 LEU A CD1 1 
ATOM   1620 C  CD2 . LEU A 1 220 ? 147.322 93.461  146.580 1.00 97.96  ? 220 LEU A CD2 1 
ATOM   1621 N  N   . ASP A 1 221 ? 149.812 94.551  144.172 1.00 89.25  ? 221 ASP A N   1 
ATOM   1622 C  CA  . ASP A 1 221 ? 149.265 95.757  143.563 1.00 86.22  ? 221 ASP A CA  1 
ATOM   1623 C  C   . ASP A 1 221 ? 149.798 95.963  142.151 1.00 86.60  ? 221 ASP A C   1 
ATOM   1624 O  O   . ASP A 1 221 ? 149.019 96.099  141.204 1.00 87.38  ? 221 ASP A O   1 
ATOM   1625 C  CB  . ASP A 1 221 ? 149.578 96.974  144.432 1.00 86.20  ? 221 ASP A CB  1 
ATOM   1626 C  CG  . ASP A 1 221 ? 148.436 97.339  145.350 1.00 87.63  ? 221 ASP A CG  1 
ATOM   1627 O  OD1 . ASP A 1 221 ? 147.370 97.742  144.841 1.00 87.31  ? 221 ASP A OD1 1 
ATOM   1628 O  OD2 . ASP A 1 221 ? 148.603 97.223  146.581 1.00 88.00  ? 221 ASP A OD2 1 
ATOM   1629 N  N   . ILE A 1 222 ? 151.122 95.986  141.991 1.00 83.68  ? 222 ILE A N   1 
ATOM   1630 C  CA  . ILE A 1 222 ? 151.710 96.301  140.691 1.00 84.43  ? 222 ILE A CA  1 
ATOM   1631 C  C   . ILE A 1 222 ? 151.336 95.243  139.660 1.00 82.97  ? 222 ILE A C   1 
ATOM   1632 O  O   . ILE A 1 222 ? 150.903 95.563  138.547 1.00 83.85  ? 222 ILE A O   1 
ATOM   1633 C  CB  . ILE A 1 222 ? 153.236 96.455  140.812 1.00 82.75  ? 222 ILE A CB  1 
ATOM   1634 C  CG1 . ILE A 1 222 ? 153.589 97.787  141.464 1.00 77.84  ? 222 ILE A CG1 1 
ATOM   1635 C  CG2 . ILE A 1 222 ? 153.890 96.380  139.450 1.00 80.95  ? 222 ILE A CG2 1 
ATOM   1636 C  CD1 . ILE A 1 222 ? 155.057 98.115  141.409 1.00 75.99  ? 222 ILE A CD1 1 
ATOM   1637 N  N   . LEU A 1 223 ? 151.482 93.965  140.014 1.00 77.89  ? 223 LEU A N   1 
ATOM   1638 C  CA  . LEU A 1 223 ? 151.274 92.906  139.033 1.00 78.52  ? 223 LEU A CA  1 
ATOM   1639 C  C   . LEU A 1 223 ? 149.797 92.572  138.860 1.00 79.28  ? 223 LEU A C   1 
ATOM   1640 O  O   . LEU A 1 223 ? 149.247 92.703  137.763 1.00 83.25  ? 223 LEU A O   1 
ATOM   1641 C  CB  . LEU A 1 223 ? 152.060 91.651  139.426 1.00 80.34  ? 223 LEU A CB  1 
ATOM   1642 C  CG  . LEU A 1 223 ? 153.547 91.524  139.073 1.00 81.75  ? 223 LEU A CG  1 
ATOM   1643 C  CD1 . LEU A 1 223 ? 154.290 92.846  139.125 1.00 79.04  ? 223 LEU A CD1 1 
ATOM   1644 C  CD2 . LEU A 1 223 ? 154.218 90.498  139.974 1.00 80.67  ? 223 LEU A CD2 1 
ATOM   1645 N  N   . LEU A 1 224 ? 149.137 92.128  139.929 1.00 78.22  ? 224 LEU A N   1 
ATOM   1646 C  CA  . LEU A 1 224 ? 147.810 91.542  139.767 1.00 80.42  ? 224 LEU A CA  1 
ATOM   1647 C  C   . LEU A 1 224 ? 146.738 92.606  139.556 1.00 77.38  ? 224 LEU A C   1 
ATOM   1648 O  O   . LEU A 1 224 ? 146.107 92.657  138.499 1.00 77.86  ? 224 LEU A O   1 
ATOM   1649 C  CB  . LEU A 1 224 ? 147.472 90.659  140.969 1.00 80.74  ? 224 LEU A CB  1 
ATOM   1650 C  CG  . LEU A 1 224 ? 147.755 89.170  140.755 1.00 79.28  ? 224 LEU A CG  1 
ATOM   1651 C  CD1 . LEU A 1 224 ? 149.240 88.875  140.878 1.00 79.45  ? 224 LEU A CD1 1 
ATOM   1652 C  CD2 . LEU A 1 224 ? 146.955 88.321  141.724 1.00 79.06  ? 224 LEU A CD2 1 
ATOM   1653 N  N   . CYS A 1 225 ? 146.528 93.478  140.541 1.00 74.91  ? 225 CYS A N   1 
ATOM   1654 C  CA  . CYS A 1 225 ? 145.435 94.441  140.440 1.00 73.67  ? 225 CYS A CA  1 
ATOM   1655 C  C   . CYS A 1 225 ? 145.690 95.450  139.326 1.00 74.63  ? 225 CYS A C   1 
ATOM   1656 O  O   . CYS A 1 225 ? 144.933 95.523  138.351 1.00 76.91  ? 225 CYS A O   1 
ATOM   1657 C  CB  . CYS A 1 225 ? 145.235 95.150  141.780 1.00 76.55  ? 225 CYS A CB  1 
ATOM   1658 S  SG  . CYS A 1 225 ? 145.223 94.053  143.215 1.00 84.20  ? 225 CYS A SG  1 
ATOM   1659 N  N   . ASN A 1 226 ? 146.765 96.232  139.449 1.00 67.14  ? 226 ASN A N   1 
ATOM   1660 C  CA  . ASN A 1 226 ? 147.055 97.253  138.448 1.00 65.33  ? 226 ASN A CA  1 
ATOM   1661 C  C   . ASN A 1 226 ? 147.332 96.635  137.084 1.00 66.56  ? 226 ASN A C   1 
ATOM   1662 O  O   . ASN A 1 226 ? 146.832 97.120  136.066 1.00 67.46  ? 226 ASN A O   1 
ATOM   1663 C  CB  . ASN A 1 226 ? 148.240 98.107  138.895 1.00 65.56  ? 226 ASN A CB  1 
ATOM   1664 C  CG  . ASN A 1 226 ? 147.996 98.793  140.220 1.00 66.74  ? 226 ASN A CG  1 
ATOM   1665 O  OD1 . ASN A 1 226 ? 146.970 98.582  140.862 1.00 66.27  ? 226 ASN A OD1 1 
ATOM   1666 N  ND2 . ASN A 1 226 ? 148.942 99.622  140.637 1.00 64.42  ? 226 ASN A ND2 1 
ATOM   1667 N  N   . GLY A 1 227 ? 148.129 95.567  137.042 1.00 62.98  ? 227 GLY A N   1 
ATOM   1668 C  CA  . GLY A 1 227 ? 148.462 94.957  135.766 1.00 59.51  ? 227 GLY A CA  1 
ATOM   1669 C  C   . GLY A 1 227 ? 147.260 94.346  135.073 1.00 59.50  ? 227 GLY A C   1 
ATOM   1670 O  O   . GLY A 1 227 ? 147.090 94.499  133.861 1.00 63.70  ? 227 GLY A O   1 
ATOM   1671 N  N   . GLY A 1 228 ? 146.413 93.646  135.826 1.00 50.82  ? 228 GLY A N   1 
ATOM   1672 C  CA  . GLY A 1 228 ? 145.204 93.094  135.242 1.00 52.85  ? 228 GLY A CA  1 
ATOM   1673 C  C   . GLY A 1 228 ? 144.249 94.170  134.769 1.00 56.41  ? 228 GLY A C   1 
ATOM   1674 O  O   . GLY A 1 228 ? 143.638 94.046  133.704 1.00 58.80  ? 228 GLY A O   1 
ATOM   1675 N  N   . GLY A 1 229 ? 144.111 95.245  135.547 1.00 58.54  ? 229 GLY A N   1 
ATOM   1676 C  CA  . GLY A 1 229 ? 143.286 96.353  135.102 1.00 55.60  ? 229 GLY A CA  1 
ATOM   1677 C  C   . GLY A 1 229 ? 143.802 96.971  133.819 1.00 58.03  ? 229 GLY A C   1 
ATOM   1678 O  O   . GLY A 1 229 ? 143.037 97.225  132.889 1.00 62.19  ? 229 GLY A O   1 
ATOM   1679 N  N   . ILE A 1 230 ? 145.114 97.203  133.745 1.00 51.77  ? 230 ILE A N   1 
ATOM   1680 C  CA  . ILE A 1 230 ? 145.698 97.799  132.548 1.00 46.81  ? 230 ILE A CA  1 
ATOM   1681 C  C   . ILE A 1 230 ? 145.503 96.882  131.350 1.00 55.63  ? 230 ILE A C   1 
ATOM   1682 O  O   . ILE A 1 230 ? 145.149 97.333  130.254 1.00 62.81  ? 230 ILE A O   1 
ATOM   1683 C  CB  . ILE A 1 230 ? 147.186 98.116  132.781 1.00 45.19  ? 230 ILE A CB  1 
ATOM   1684 C  CG1 . ILE A 1 230 ? 147.343 99.199  133.841 1.00 43.14  ? 230 ILE A CG1 1 
ATOM   1685 C  CG2 . ILE A 1 230 ? 147.845 98.566  131.496 1.00 53.92  ? 230 ILE A CG2 1 
ATOM   1686 C  CD1 . ILE A 1 230 ? 148.767 99.422  134.249 1.00 47.52  ? 230 ILE A CD1 1 
ATOM   1687 N  N   . TRP A 1 231 ? 145.725 95.581  131.540 1.00 51.20  ? 231 TRP A N   1 
ATOM   1688 C  CA  . TRP A 1 231 ? 145.558 94.628  130.450 1.00 48.70  ? 231 TRP A CA  1 
ATOM   1689 C  C   . TRP A 1 231 ? 144.123 94.616  129.946 1.00 52.40  ? 231 TRP A C   1 
ATOM   1690 O  O   . TRP A 1 231 ? 143.878 94.658  128.735 1.00 57.58  ? 231 TRP A O   1 
ATOM   1691 C  CB  . TRP A 1 231 ? 145.975 93.236  130.919 1.00 53.46  ? 231 TRP A CB  1 
ATOM   1692 C  CG  . TRP A 1 231 ? 146.189 92.256  129.816 1.00 58.10  ? 231 TRP A CG  1 
ATOM   1693 C  CD1 . TRP A 1 231 ? 146.250 92.522  128.481 1.00 57.54  ? 231 TRP A CD1 1 
ATOM   1694 C  CD2 . TRP A 1 231 ? 146.385 90.845  129.954 1.00 55.85  ? 231 TRP A CD2 1 
ATOM   1695 N  NE1 . TRP A 1 231 ? 146.468 91.364  127.778 1.00 52.83  ? 231 TRP A NE1 1 
ATOM   1696 C  CE2 . TRP A 1 231 ? 146.555 90.320  128.661 1.00 55.67  ? 231 TRP A CE2 1 
ATOM   1697 C  CE3 . TRP A 1 231 ? 146.434 89.976  131.048 1.00 55.34  ? 231 TRP A CE3 1 
ATOM   1698 C  CZ2 . TRP A 1 231 ? 146.767 88.964  128.430 1.00 60.54  ? 231 TRP A CZ2 1 
ATOM   1699 C  CZ3 . TRP A 1 231 ? 146.645 88.632  130.818 1.00 55.77  ? 231 TRP A CZ3 1 
ATOM   1700 C  CH2 . TRP A 1 231 ? 146.809 88.138  129.520 1.00 60.11  ? 231 TRP A CH2 1 
ATOM   1701 N  N   . LEU A 1 232 ? 143.156 94.564  130.864 1.00 52.51  ? 232 LEU A N   1 
ATOM   1702 C  CA  . LEU A 1 232 ? 141.756 94.540  130.457 1.00 53.16  ? 232 LEU A CA  1 
ATOM   1703 C  C   . LEU A 1 232 ? 141.363 95.835  129.762 1.00 49.99  ? 232 LEU A C   1 
ATOM   1704 O  O   . LEU A 1 232 ? 140.638 95.816  128.760 1.00 56.89  ? 232 LEU A O   1 
ATOM   1705 C  CB  . LEU A 1 232 ? 140.863 94.288  131.667 1.00 55.78  ? 232 LEU A CB  1 
ATOM   1706 C  CG  . LEU A 1 232 ? 139.385 94.094  131.353 1.00 55.77  ? 232 LEU A CG  1 
ATOM   1707 C  CD1 . LEU A 1 232 ? 139.158 92.709  130.784 1.00 54.85  ? 232 LEU A CD1 1 
ATOM   1708 C  CD2 . LEU A 1 232 ? 138.543 94.316  132.595 1.00 55.07  ? 232 LEU A CD2 1 
ATOM   1709 N  N   . GLY A 1 233 ? 141.834 96.970  130.274 1.00 46.73  ? 233 GLY A N   1 
ATOM   1710 C  CA  . GLY A 1 233 ? 141.518 98.237  129.642 1.00 44.58  ? 233 GLY A CA  1 
ATOM   1711 C  C   . GLY A 1 233 ? 142.069 98.339  128.236 1.00 52.38  ? 233 GLY A C   1 
ATOM   1712 O  O   . GLY A 1 233 ? 141.380 98.796  127.324 1.00 55.31  ? 233 GLY A O   1 
ATOM   1713 N  N   . MET A 1 234 ? 143.312 97.901  128.033 1.00 58.45  ? 234 MET A N   1 
ATOM   1714 C  CA  . MET A 1 234 ? 143.890 97.968  126.695 1.00 57.00  ? 234 MET A CA  1 
ATOM   1715 C  C   . MET A 1 234 ? 143.247 96.961  125.747 1.00 58.17  ? 234 MET A C   1 
ATOM   1716 O  O   . MET A 1 234 ? 143.108 97.240  124.550 1.00 61.25  ? 234 MET A O   1 
ATOM   1717 C  CB  . MET A 1 234 ? 145.401 97.762  126.765 1.00 53.90  ? 234 MET A CB  1 
ATOM   1718 C  CG  . MET A 1 234 ? 146.104 98.770  127.650 1.00 51.24  ? 234 MET A CG  1 
ATOM   1719 S  SD  . MET A 1 234 ? 146.468 100.300 126.785 1.00 67.82  ? 234 MET A SD  1 
ATOM   1720 C  CE  . MET A 1 234 ? 146.961 99.666  125.191 1.00 58.84  ? 234 MET A CE  1 
ATOM   1721 N  N   . VAL A 1 235 ? 142.832 95.799  126.257 1.00 55.66  ? 235 VAL A N   1 
ATOM   1722 C  CA  . VAL A 1 235 ? 142.115 94.841  125.419 1.00 58.01  ? 235 VAL A CA  1 
ATOM   1723 C  C   . VAL A 1 235 ? 140.778 95.419  124.971 1.00 60.39  ? 235 VAL A C   1 
ATOM   1724 O  O   . VAL A 1 235 ? 140.394 95.308  123.798 1.00 66.41  ? 235 VAL A O   1 
ATOM   1725 C  CB  . VAL A 1 235 ? 141.938 93.510  126.169 1.00 55.99  ? 235 VAL A CB  1 
ATOM   1726 C  CG1 . VAL A 1 235 ? 140.823 92.693  125.549 1.00 56.35  ? 235 VAL A CG1 1 
ATOM   1727 C  CG2 . VAL A 1 235 ? 143.239 92.732  126.166 1.00 59.92  ? 235 VAL A CG2 1 
ATOM   1728 N  N   . VAL A 1 236 ? 140.053 96.056  125.892 1.00 54.66  ? 236 VAL A N   1 
ATOM   1729 C  CA  . VAL A 1 236 ? 138.791 96.685  125.522 1.00 47.90  ? 236 VAL A CA  1 
ATOM   1730 C  C   . VAL A 1 236 ? 139.024 97.859  124.577 1.00 54.53  ? 236 VAL A C   1 
ATOM   1731 O  O   . VAL A 1 236 ? 138.200 98.115  123.697 1.00 61.55  ? 236 VAL A O   1 
ATOM   1732 C  CB  . VAL A 1 236 ? 138.010 97.101  126.779 1.00 49.73  ? 236 VAL A CB  1 
ATOM   1733 C  CG1 . VAL A 1 236 ? 136.749 97.844  126.404 1.00 52.06  ? 236 VAL A CG1 1 
ATOM   1734 C  CG2 . VAL A 1 236 ? 137.658 95.878  127.592 1.00 51.70  ? 236 VAL A CG2 1 
ATOM   1735 N  N   . CYS A 1 237 ? 140.128 98.595  124.734 1.00 59.61  ? 237 CYS A N   1 
ATOM   1736 C  CA  . CYS A 1 237 ? 140.460 99.641  123.768 1.00 55.88  ? 237 CYS A CA  1 
ATOM   1737 C  C   . CYS A 1 237 ? 140.638 99.062  122.376 1.00 61.71  ? 237 CYS A C   1 
ATOM   1738 O  O   . CYS A 1 237 ? 140.107 99.593  121.395 1.00 65.58  ? 237 CYS A O   1 
ATOM   1739 C  CB  . CYS A 1 237 ? 141.739 100.364 124.173 1.00 58.96  ? 237 CYS A CB  1 
ATOM   1740 S  SG  . CYS A 1 237 ? 141.619 101.368 125.620 1.00 84.06  ? 237 CYS A SG  1 
ATOM   1741 N  N   . ARG A 1 238 ? 141.408 97.978  122.273 1.00 66.04  ? 238 ARG A N   1 
ATOM   1742 C  CA  . ARG A 1 238 ? 141.631 97.357  120.974 1.00 66.85  ? 238 ARG A CA  1 
ATOM   1743 C  C   . ARG A 1 238 ? 140.318 96.893  120.365 1.00 67.97  ? 238 ARG A C   1 
ATOM   1744 O  O   . ARG A 1 238 ? 140.088 97.060  119.163 1.00 72.54  ? 238 ARG A O   1 
ATOM   1745 C  CB  . ARG A 1 238 ? 142.603 96.188  121.113 1.00 68.66  ? 238 ARG A CB  1 
ATOM   1746 C  CG  . ARG A 1 238 ? 143.553 96.027  119.942 1.00 72.11  ? 238 ARG A CG  1 
ATOM   1747 C  CD  . ARG A 1 238 ? 144.441 94.810  120.133 1.00 72.93  ? 238 ARG A CD  1 
ATOM   1748 N  NE  . ARG A 1 238 ? 145.374 94.990  121.239 1.00 74.47  ? 238 ARG A NE  1 
ATOM   1749 C  CZ  . ARG A 1 238 ? 145.478 94.168  122.273 1.00 72.05  ? 238 ARG A CZ  1 
ATOM   1750 N  NH1 . ARG A 1 238 ? 144.715 93.092  122.380 1.00 70.60  ? 238 ARG A NH1 1 
ATOM   1751 N  NH2 . ARG A 1 238 ? 146.367 94.434  123.226 1.00 70.92  ? 238 ARG A NH2 1 
ATOM   1752 N  N   . PHE A 1 239 ? 139.438 96.316  121.183 1.00 61.09  ? 239 PHE A N   1 
ATOM   1753 C  CA  . PHE A 1 239 ? 138.151 95.857  120.670 1.00 61.37  ? 239 PHE A CA  1 
ATOM   1754 C  C   . PHE A 1 239 ? 137.279 97.027  120.220 1.00 63.31  ? 239 PHE A C   1 
ATOM   1755 O  O   . PHE A 1 239 ? 136.702 97.000  119.128 1.00 68.77  ? 239 PHE A O   1 
ATOM   1756 C  CB  . PHE A 1 239 ? 137.436 95.027  121.731 1.00 57.45  ? 239 PHE A CB  1 
ATOM   1757 C  CG  . PHE A 1 239 ? 136.049 94.627  121.348 1.00 60.82  ? 239 PHE A CG  1 
ATOM   1758 C  CD1 . PHE A 1 239 ? 135.830 93.790  120.270 1.00 62.85  ? 239 PHE A CD1 1 
ATOM   1759 C  CD2 . PHE A 1 239 ? 134.961 95.087  122.065 1.00 63.97  ? 239 PHE A CD2 1 
ATOM   1760 C  CE1 . PHE A 1 239 ? 134.551 93.419  119.913 1.00 63.97  ? 239 PHE A CE1 1 
ATOM   1761 C  CE2 . PHE A 1 239 ? 133.680 94.720  121.713 1.00 66.35  ? 239 PHE A CE2 1 
ATOM   1762 C  CZ  . PHE A 1 239 ? 133.475 93.884  120.636 1.00 67.03  ? 239 PHE A CZ  1 
ATOM   1763 N  N   . LEU A 1 240 ? 137.183 98.071  121.045 1.00 55.88  ? 240 LEU A N   1 
ATOM   1764 C  CA  . LEU A 1 240 ? 136.264 99.171  120.776 1.00 52.38  ? 240 LEU A CA  1 
ATOM   1765 C  C   . LEU A 1 240 ? 136.721 100.033 119.610 1.00 54.09  ? 240 LEU A C   1 
ATOM   1766 O  O   . LEU A 1 240 ? 135.884 100.551 118.864 1.00 57.96  ? 240 LEU A O   1 
ATOM   1767 C  CB  . LEU A 1 240 ? 136.108 100.036 122.024 1.00 50.92  ? 240 LEU A CB  1 
ATOM   1768 C  CG  . LEU A 1 240 ? 135.138 99.563  123.102 1.00 49.32  ? 240 LEU A CG  1 
ATOM   1769 C  CD1 . LEU A 1 240 ? 135.208 100.490 124.293 1.00 47.43  ? 240 LEU A CD1 1 
ATOM   1770 C  CD2 . LEU A 1 240 ? 133.731 99.513  122.556 1.00 54.17  ? 240 LEU A CD2 1 
ATOM   1771 N  N   . GLU A 1 241 ? 138.027 100.224 119.444 1.00 61.64  ? 241 GLU A N   1 
ATOM   1772 C  CA  . GLU A 1 241 ? 138.501 101.096 118.379 1.00 66.27  ? 241 GLU A CA  1 
ATOM   1773 C  C   . GLU A 1 241 ? 138.515 100.417 117.018 1.00 68.47  ? 241 GLU A C   1 
ATOM   1774 O  O   . GLU A 1 241 ? 138.628 101.110 116.003 1.00 71.63  ? 241 GLU A O   1 
ATOM   1775 C  CB  . GLU A 1 241 ? 139.897 101.625 118.713 1.00 65.82  ? 241 GLU A CB  1 
ATOM   1776 C  CG  . GLU A 1 241 ? 141.033 100.782 118.181 1.00 64.55  ? 241 GLU A CG  1 
ATOM   1777 C  CD  . GLU A 1 241 ? 142.384 101.345 118.557 1.00 65.79  ? 241 GLU A CD  1 
ATOM   1778 O  OE1 . GLU A 1 241 ? 142.422 102.335 119.315 1.00 66.89  ? 241 GLU A OE1 1 
ATOM   1779 O  OE2 . GLU A 1 241 ? 143.407 100.800 118.094 1.00 67.61  ? 241 GLU A OE2 1 
ATOM   1780 N  N   . MET A 1 242 ? 138.403 99.091  116.969 1.00 69.38  ? 242 MET A N   1 
ATOM   1781 C  CA  . MET A 1 242 ? 138.304 98.354  115.718 1.00 70.02  ? 242 MET A CA  1 
ATOM   1782 C  C   . MET A 1 242 ? 136.874 97.949  115.393 1.00 73.05  ? 242 MET A C   1 
ATOM   1783 O  O   . MET A 1 242 ? 136.649 97.234  114.413 1.00 74.78  ? 242 MET A O   1 
ATOM   1784 C  CB  . MET A 1 242 ? 139.198 97.115  115.762 1.00 69.19  ? 242 MET A CB  1 
ATOM   1785 C  CG  . MET A 1 242 ? 140.549 97.305  115.106 1.00 73.56  ? 242 MET A CG  1 
ATOM   1786 S  SD  . MET A 1 242 ? 141.591 95.836  115.195 1.00 87.01  ? 242 MET A SD  1 
ATOM   1787 C  CE  . MET A 1 242 ? 141.052 95.113  116.741 1.00 70.52  ? 242 MET A CE  1 
ATOM   1788 N  N   . ARG A 1 243 ? 135.908 98.386  116.194 1.00 65.18  ? 243 ARG A N   1 
ATOM   1789 C  CA  . ARG A 1 243 ? 134.517 98.010  115.997 1.00 62.01  ? 243 ARG A CA  1 
ATOM   1790 C  C   . ARG A 1 243 ? 133.857 98.910  114.963 1.00 66.05  ? 243 ARG A C   1 
ATOM   1791 O  O   . ARG A 1 243 ? 134.139 100.109 114.891 1.00 67.86  ? 243 ARG A O   1 
ATOM   1792 C  CB  . ARG A 1 243 ? 133.759 98.088  117.322 1.00 59.68  ? 243 ARG A CB  1 
ATOM   1793 C  CG  . ARG A 1 243 ? 132.267 97.883  117.203 1.00 61.73  ? 243 ARG A CG  1 
ATOM   1794 C  CD  . ARG A 1 243 ? 131.709 97.174  118.414 1.00 61.72  ? 243 ARG A CD  1 
ATOM   1795 N  NE  . ARG A 1 243 ? 131.278 98.115  119.438 1.00 65.55  ? 243 ARG A NE  1 
ATOM   1796 C  CZ  . ARG A 1 243 ? 130.015 98.451  119.660 1.00 67.96  ? 243 ARG A CZ  1 
ATOM   1797 N  NH1 . ARG A 1 243 ? 129.030 97.955  118.930 1.00 65.09  ? 243 ARG A NH1 1 
ATOM   1798 N  NH2 . ARG A 1 243 ? 129.734 99.308  120.637 1.00 65.81  ? 243 ARG A NH2 1 
ATOM   1799 N  N   . THR A 1 244 ? 132.983 98.320  114.150 1.00 68.52  ? 244 THR A N   1 
ATOM   1800 C  CA  . THR A 1 244 ? 132.181 99.067  113.183 1.00 66.58  ? 244 THR A CA  1 
ATOM   1801 C  C   . THR A 1 244 ? 130.899 99.494  113.882 1.00 66.88  ? 244 THR A C   1 
ATOM   1802 O  O   . THR A 1 244 ? 129.995 98.684  114.098 1.00 70.38  ? 244 THR A O   1 
ATOM   1803 C  CB  . THR A 1 244 ? 131.885 98.222  111.952 1.00 67.63  ? 244 THR A CB  1 
ATOM   1804 O  OG1 . THR A 1 244 ? 130.750 97.387  112.212 1.00 70.31  ? 244 THR A OG1 1 
ATOM   1805 C  CG2 . THR A 1 244 ? 133.080 97.349  111.608 1.00 64.37  ? 244 THR A CG2 1 
ATOM   1806 N  N   . TYR A 1 245 ? 130.814 100.773 114.232 1.00 59.01  ? 245 TYR A N   1 
ATOM   1807 C  CA  . TYR A 1 245 ? 129.709 101.280 115.039 1.00 60.27  ? 245 TYR A CA  1 
ATOM   1808 C  C   . TYR A 1 245 ? 128.519 101.554 114.130 1.00 61.01  ? 245 TYR A C   1 
ATOM   1809 O  O   . TYR A 1 245 ? 128.439 102.600 113.483 1.00 61.40  ? 245 TYR A O   1 
ATOM   1810 C  CB  . TYR A 1 245 ? 130.138 102.529 115.799 1.00 59.27  ? 245 TYR A CB  1 
ATOM   1811 C  CG  . TYR A 1 245 ? 131.151 102.247 116.883 1.00 57.76  ? 245 TYR A CG  1 
ATOM   1812 C  CD1 . TYR A 1 245 ? 130.756 101.765 118.121 1.00 55.79  ? 245 TYR A CD1 1 
ATOM   1813 C  CD2 . TYR A 1 245 ? 132.503 102.444 116.661 1.00 59.35  ? 245 TYR A CD2 1 
ATOM   1814 C  CE1 . TYR A 1 245 ? 131.679 101.498 119.108 1.00 56.49  ? 245 TYR A CE1 1 
ATOM   1815 C  CE2 . TYR A 1 245 ? 133.432 102.182 117.643 1.00 59.28  ? 245 TYR A CE2 1 
ATOM   1816 C  CZ  . TYR A 1 245 ? 133.015 101.708 118.863 1.00 60.18  ? 245 TYR A CZ  1 
ATOM   1817 O  OH  . TYR A 1 245 ? 133.940 101.446 119.843 1.00 61.67  ? 245 TYR A OH  1 
ATOM   1818 N  N   . HIS A 1 246 ? 127.590 100.603 114.078 1.00 63.86  ? 246 HIS A N   1 
ATOM   1819 C  CA  . HIS A 1 246 ? 126.351 100.730 113.322 1.00 63.97  ? 246 HIS A CA  1 
ATOM   1820 C  C   . HIS A 1 246 ? 125.194 100.670 114.306 1.00 62.90  ? 246 HIS A C   1 
ATOM   1821 O  O   . HIS A 1 246 ? 125.003 99.650  114.976 1.00 64.83  ? 246 HIS A O   1 
ATOM   1822 C  CB  . HIS A 1 246 ? 126.234 99.622  112.273 1.00 66.24  ? 246 HIS A CB  1 
ATOM   1823 C  CG  . HIS A 1 246 ? 124.924 99.608  111.550 1.00 69.51  ? 246 HIS A CG  1 
ATOM   1824 N  ND1 . HIS A 1 246 ? 124.499 100.655 110.761 1.00 71.13  ? 246 HIS A ND1 1 
ATOM   1825 C  CD2 . HIS A 1 246 ? 123.946 98.674  111.496 1.00 67.91  ? 246 HIS A CD2 1 
ATOM   1826 C  CE1 . HIS A 1 246 ? 123.314 100.366 110.253 1.00 68.26  ? 246 HIS A CE1 1 
ATOM   1827 N  NE2 . HIS A 1 246 ? 122.956 99.170  110.683 1.00 68.62  ? 246 HIS A NE2 1 
ATOM   1828 N  N   . TRP A 1 247 ? 124.427 101.753 114.393 1.00 53.08  ? 247 TRP A N   1 
ATOM   1829 C  CA  . TRP A 1 247 ? 123.412 101.918 115.432 1.00 55.91  ? 247 TRP A CA  1 
ATOM   1830 C  C   . TRP A 1 247 ? 122.031 101.974 114.794 1.00 54.61  ? 247 TRP A C   1 
ATOM   1831 O  O   . TRP A 1 247 ? 121.582 103.038 114.359 1.00 56.83  ? 247 TRP A O   1 
ATOM   1832 C  CB  . TRP A 1 247 ? 123.687 103.169 116.261 1.00 55.22  ? 247 TRP A CB  1 
ATOM   1833 C  CG  . TRP A 1 247 ? 124.936 103.058 117.055 1.00 49.69  ? 247 TRP A CG  1 
ATOM   1834 C  CD1 . TRP A 1 247 ? 126.080 103.769 116.881 1.00 46.87  ? 247 TRP A CD1 1 
ATOM   1835 C  CD2 . TRP A 1 247 ? 125.179 102.161 118.140 1.00 49.00  ? 247 TRP A CD2 1 
ATOM   1836 N  NE1 . TRP A 1 247 ? 127.022 103.377 117.795 1.00 50.11  ? 247 TRP A NE1 1 
ATOM   1837 C  CE2 . TRP A 1 247 ? 126.493 102.388 118.580 1.00 50.32  ? 247 TRP A CE2 1 
ATOM   1838 C  CE3 . TRP A 1 247 ? 124.412 101.188 118.783 1.00 50.91  ? 247 TRP A CE3 1 
ATOM   1839 C  CZ2 . TRP A 1 247 ? 127.057 101.681 119.634 1.00 49.69  ? 247 TRP A CZ2 1 
ATOM   1840 C  CZ3 . TRP A 1 247 ? 124.971 100.489 119.825 1.00 51.95  ? 247 TRP A CZ3 1 
ATOM   1841 C  CH2 . TRP A 1 247 ? 126.281 100.739 120.243 1.00 49.60  ? 247 TRP A CH2 1 
ATOM   1842 N  N   . ALA A 1 248 ? 121.355 100.831 114.748 1.00 62.29  ? 248 ALA A N   1 
ATOM   1843 C  CA  . ALA A 1 248 ? 119.983 100.802 114.270 1.00 64.27  ? 248 ALA A CA  1 
ATOM   1844 C  C   . ALA A 1 248 ? 119.054 101.431 115.300 1.00 65.28  ? 248 ALA A C   1 
ATOM   1845 O  O   . ALA A 1 248 ? 119.273 101.332 116.509 1.00 66.42  ? 248 ALA A O   1 
ATOM   1846 C  CB  . ALA A 1 248 ? 119.549 99.369  113.975 1.00 63.48  ? 248 ALA A CB  1 
ATOM   1847 N  N   . SER A 1 249 ? 118.010 102.090 114.809 1.00 72.96  ? 249 SER A N   1 
ATOM   1848 C  CA  . SER A 1 249 ? 117.058 102.735 115.700 1.00 73.22  ? 249 SER A CA  1 
ATOM   1849 C  C   . SER A 1 249 ? 116.285 101.697 116.505 1.00 72.63  ? 249 SER A C   1 
ATOM   1850 O  O   . SER A 1 249 ? 116.042 100.578 116.049 1.00 70.89  ? 249 SER A O   1 
ATOM   1851 C  CB  . SER A 1 249 ? 116.089 103.608 114.910 1.00 71.80  ? 249 SER A CB  1 
ATOM   1852 O  OG  . SER A 1 249 ? 115.140 104.206 115.774 1.00 74.41  ? 249 SER A OG  1 
ATOM   1853 N  N   . PHE A 1 250 ? 115.898 102.085 117.721 1.00 69.00  ? 250 PHE A N   1 
ATOM   1854 C  CA  . PHE A 1 250 ? 115.197 101.164 118.609 1.00 69.12  ? 250 PHE A CA  1 
ATOM   1855 C  C   . PHE A 1 250 ? 113.853 100.748 118.030 1.00 69.98  ? 250 PHE A C   1 
ATOM   1856 O  O   . PHE A 1 250 ? 113.431 99.597  118.184 1.00 71.22  ? 250 PHE A O   1 
ATOM   1857 C  CB  . PHE A 1 250 ? 115.013 101.804 119.983 1.00 68.71  ? 250 PHE A CB  1 
ATOM   1858 C  CG  . PHE A 1 250 ? 114.377 100.898 120.996 1.00 67.53  ? 250 PHE A CG  1 
ATOM   1859 C  CD1 . PHE A 1 250 ? 113.004 100.849 121.137 1.00 67.64  ? 250 PHE A CD1 1 
ATOM   1860 C  CD2 . PHE A 1 250 ? 115.155 100.104 121.814 1.00 67.35  ? 250 PHE A CD2 1 
ATOM   1861 C  CE1 . PHE A 1 250 ? 112.426 100.023 122.067 1.00 69.07  ? 250 PHE A CE1 1 
ATOM   1862 C  CE2 . PHE A 1 250 ? 114.578 99.277  122.744 1.00 65.78  ? 250 PHE A CE2 1 
ATOM   1863 C  CZ  . PHE A 1 250 ? 113.214 99.236  122.871 1.00 66.48  ? 250 PHE A CZ  1 
ATOM   1864 N  N   . LYS A 1 251 ? 113.155 101.678 117.378 1.00 74.98  ? 251 LYS A N   1 
ATOM   1865 C  CA  . LYS A 1 251 ? 111.847 101.360 116.817 1.00 77.74  ? 251 LYS A CA  1 
ATOM   1866 C  C   . LYS A 1 251 ? 111.953 100.374 115.662 1.00 77.70  ? 251 LYS A C   1 
ATOM   1867 O  O   . LYS A 1 251 ? 111.062 99.536  115.483 1.00 78.15  ? 251 LYS A O   1 
ATOM   1868 C  CB  . LYS A 1 251 ? 111.151 102.641 116.360 1.00 75.86  ? 251 LYS A CB  1 
ATOM   1869 C  CG  . LYS A 1 251 ? 111.332 103.812 117.310 1.00 74.62  ? 251 LYS A CG  1 
ATOM   1870 C  CD  . LYS A 1 251 ? 111.013 105.132 116.631 1.00 75.48  ? 251 LYS A CD  1 
ATOM   1871 C  CE  . LYS A 1 251 ? 111.852 105.322 115.381 1.00 76.25  ? 251 LYS A CE  1 
ATOM   1872 N  NZ  . LYS A 1 251 ? 111.554 106.610 114.699 1.00 77.23  ? 251 LYS A NZ  1 
ATOM   1873 N  N   . ASP A 1 252 ? 113.027 100.456 114.875 1.00 76.26  ? 252 ASP A N   1 
ATOM   1874 C  CA  . ASP A 1 252 ? 113.126 99.643  113.667 1.00 77.53  ? 252 ASP A CA  1 
ATOM   1875 C  C   . ASP A 1 252 ? 113.304 98.165  113.992 1.00 77.88  ? 252 ASP A C   1 
ATOM   1876 O  O   . ASP A 1 252 ? 112.794 97.303  113.266 1.00 80.22  ? 252 ASP A O   1 
ATOM   1877 C  CB  . ASP A 1 252 ? 114.274 100.145 112.796 1.00 79.29  ? 252 ASP A CB  1 
ATOM   1878 C  CG  . ASP A 1 252 ? 114.160 101.620 112.484 1.00 79.77  ? 252 ASP A CG  1 
ATOM   1879 O  OD1 . ASP A 1 252 ? 113.149 102.233 112.885 1.00 77.64  ? 252 ASP A OD1 1 
ATOM   1880 O  OD2 . ASP A 1 252 ? 115.078 102.166 111.838 1.00 79.55  ? 252 ASP A OD2 1 
ATOM   1881 N  N   . ILE A 1 253 ? 114.026 97.849  115.066 1.00 76.27  ? 253 ILE A N   1 
ATOM   1882 C  CA  . ILE A 1 253 ? 114.252 96.454  115.426 1.00 76.99  ? 253 ILE A CA  1 
ATOM   1883 C  C   . ILE A 1 253 ? 112.928 95.807  115.806 1.00 79.27  ? 253 ILE A C   1 
ATOM   1884 O  O   . ILE A 1 253 ? 112.148 96.362  116.591 1.00 78.62  ? 253 ILE A O   1 
ATOM   1885 C  CB  . ILE A 1 253 ? 115.269 96.342  116.569 1.00 76.66  ? 253 ILE A CB  1 
ATOM   1886 C  CG1 . ILE A 1 253 ? 116.568 97.059  116.207 1.00 76.46  ? 253 ILE A CG1 1 
ATOM   1887 C  CG2 . ILE A 1 253 ? 115.548 94.888  116.884 1.00 76.95  ? 253 ILE A CG2 1 
ATOM   1888 C  CD1 . ILE A 1 253 ? 117.113 97.907  117.321 1.00 74.87  ? 253 ILE A CD1 1 
ATOM   1889 N  N   . HIS A 1 254 ? 112.670 94.626  115.251 1.00 82.44  ? 254 HIS A N   1 
ATOM   1890 C  CA  . HIS A 1 254 ? 111.420 93.912  115.476 1.00 81.47  ? 254 HIS A CA  1 
ATOM   1891 C  C   . HIS A 1 254 ? 111.537 92.821  116.531 1.00 82.42  ? 254 HIS A C   1 
ATOM   1892 O  O   . HIS A 1 254 ? 110.636 92.674  117.362 1.00 82.00  ? 254 HIS A O   1 
ATOM   1893 C  CB  . HIS A 1 254 ? 110.923 93.305  114.161 1.00 80.36  ? 254 HIS A CB  1 
ATOM   1894 C  CG  . HIS A 1 254 ? 110.802 94.299  113.049 1.00 82.89  ? 254 HIS A CG  1 
ATOM   1895 N  ND1 . HIS A 1 254 ? 109.829 95.275  113.026 1.00 81.41  ? 254 HIS A ND1 1 
ATOM   1896 C  CD2 . HIS A 1 254 ? 111.536 94.474  111.924 1.00 83.25  ? 254 HIS A CD2 1 
ATOM   1897 C  CE1 . HIS A 1 254 ? 109.967 96.005  111.934 1.00 80.67  ? 254 HIS A CE1 1 
ATOM   1898 N  NE2 . HIS A 1 254 ? 110.996 95.540  111.248 1.00 82.27  ? 254 HIS A NE2 1 
ATOM   1899 N  N   . THR A 1 255 ? 112.620 92.050  116.519 1.00 88.18  ? 255 THR A N   1 
ATOM   1900 C  CA  . THR A 1 255 ? 112.800 91.005  117.516 1.00 89.75  ? 255 THR A CA  1 
ATOM   1901 C  C   . THR A 1 255 ? 112.958 91.615  118.903 1.00 88.59  ? 255 THR A C   1 
ATOM   1902 O  O   . THR A 1 255 ? 113.617 92.643  119.078 1.00 86.94  ? 255 THR A O   1 
ATOM   1903 C  CB  . THR A 1 255 ? 114.019 90.145  117.180 1.00 86.44  ? 255 THR A CB  1 
ATOM   1904 O  OG1 . THR A 1 255 ? 115.205 90.948  117.236 1.00 85.47  ? 255 THR A OG1 1 
ATOM   1905 C  CG2 . THR A 1 255 ? 113.883 89.552  115.791 1.00 84.34  ? 255 THR A CG2 1 
ATOM   1906 N  N   . THR A 1 256 ? 112.338 90.972  119.895 1.00 83.39  ? 256 THR A N   1 
ATOM   1907 C  CA  . THR A 1 256 ? 112.417 91.470  121.264 1.00 84.29  ? 256 THR A CA  1 
ATOM   1908 C  C   . THR A 1 256 ? 113.844 91.419  121.790 1.00 81.83  ? 256 THR A C   1 
ATOM   1909 O  O   . THR A 1 256 ? 114.280 92.325  122.510 1.00 77.06  ? 256 THR A O   1 
ATOM   1910 C  CB  . THR A 1 256 ? 111.487 90.666  122.167 1.00 85.45  ? 256 THR A CB  1 
ATOM   1911 O  OG1 . THR A 1 256 ? 111.783 89.270  122.034 1.00 84.12  ? 256 THR A OG1 1 
ATOM   1912 C  CG2 . THR A 1 256 ? 110.040 90.908  121.777 1.00 83.89  ? 256 THR A CG2 1 
ATOM   1913 N  N   . THR A 1 257 ? 114.583 90.360  121.456 1.00 82.75  ? 257 THR A N   1 
ATOM   1914 C  CA  . THR A 1 257 ? 115.975 90.271  121.883 1.00 83.37  ? 257 THR A CA  1 
ATOM   1915 C  C   . THR A 1 257 ? 116.809 91.385  121.265 1.00 83.89  ? 257 THR A C   1 
ATOM   1916 O  O   . THR A 1 257 ? 117.700 91.938  121.919 1.00 82.47  ? 257 THR A O   1 
ATOM   1917 C  CB  . THR A 1 257 ? 116.552 88.897  121.531 1.00 83.02  ? 257 THR A CB  1 
ATOM   1918 O  OG1 . THR A 1 257 ? 117.964 88.891  121.774 1.00 84.24  ? 257 THR A OG1 1 
ATOM   1919 C  CG2 . THR A 1 257 ? 116.288 88.550  120.072 1.00 80.16  ? 257 THR A CG2 1 
ATOM   1920 N  N   . GLY A 1 258 ? 116.527 91.737  120.010 1.00 77.74  ? 258 GLY A N   1 
ATOM   1921 C  CA  . GLY A 1 258 ? 117.208 92.867  119.400 1.00 75.55  ? 258 GLY A CA  1 
ATOM   1922 C  C   . GLY A 1 258 ? 116.879 94.181  120.083 1.00 75.56  ? 258 GLY A C   1 
ATOM   1923 O  O   . GLY A 1 258 ? 117.749 95.035  120.257 1.00 73.25  ? 258 GLY A O   1 
ATOM   1924 N  N   . LYS A 1 259 ? 115.617 94.360  120.477 1.00 74.72  ? 259 LYS A N   1 
ATOM   1925 C  CA  . LYS A 1 259 ? 115.238 95.558  121.218 1.00 72.39  ? 259 LYS A CA  1 
ATOM   1926 C  C   . LYS A 1 259 ? 115.957 95.629  122.558 1.00 71.59  ? 259 LYS A C   1 
ATOM   1927 O  O   . LYS A 1 259 ? 116.415 96.699  122.969 1.00 72.16  ? 259 LYS A O   1 
ATOM   1928 C  CB  . LYS A 1 259 ? 113.725 95.593  121.421 1.00 71.72  ? 259 LYS A CB  1 
ATOM   1929 C  CG  . LYS A 1 259 ? 112.949 96.106  120.226 1.00 72.55  ? 259 LYS A CG  1 
ATOM   1930 C  CD  . LYS A 1 259 ? 111.505 96.393  120.595 1.00 72.54  ? 259 LYS A CD  1 
ATOM   1931 C  CE  . LYS A 1 259 ? 110.875 97.386  119.634 1.00 72.44  ? 259 LYS A CE  1 
ATOM   1932 N  NZ  . LYS A 1 259 ? 110.689 96.811  118.278 1.00 72.39  ? 259 LYS A NZ  1 
ATOM   1933 N  N   . ILE A 1 260 ? 116.056 94.499  123.260 1.00 68.21  ? 260 ILE A N   1 
ATOM   1934 C  CA  . ILE A 1 260 ? 116.770 94.471  124.534 1.00 66.24  ? 260 ILE A CA  1 
ATOM   1935 C  C   . ILE A 1 260 ? 118.242 94.796  124.323 1.00 67.68  ? 260 ILE A C   1 
ATOM   1936 O  O   . ILE A 1 260 ? 118.846 95.550  125.096 1.00 70.03  ? 260 ILE A O   1 
ATOM   1937 C  CB  . ILE A 1 260 ? 116.587 93.107  125.226 1.00 65.56  ? 260 ILE A CB  1 
ATOM   1938 C  CG1 . ILE A 1 260 ? 115.115 92.832  125.556 1.00 68.84  ? 260 ILE A CG1 1 
ATOM   1939 C  CG2 . ILE A 1 260 ? 117.429 93.030  126.483 1.00 65.46  ? 260 ILE A CG2 1 
ATOM   1940 C  CD1 . ILE A 1 260 ? 114.255 94.066  125.758 1.00 70.04  ? 260 ILE A CD1 1 
ATOM   1941 N  N   . LYS A 1 261 ? 118.842 94.230  123.275 1.00 66.33  ? 261 LYS A N   1 
ATOM   1942 C  CA  . LYS A 1 261 ? 120.238 94.518  122.971 1.00 61.56  ? 261 LYS A CA  1 
ATOM   1943 C  C   . LYS A 1 261 ? 120.443 95.998  122.679 1.00 61.49  ? 261 LYS A C   1 
ATOM   1944 O  O   . LYS A 1 261 ? 121.403 96.604  123.165 1.00 61.69  ? 261 LYS A O   1 
ATOM   1945 C  CB  . LYS A 1 261 ? 120.699 93.666  121.788 1.00 61.31  ? 261 LYS A CB  1 
ATOM   1946 C  CG  . LYS A 1 261 ? 122.162 93.836  121.422 1.00 63.29  ? 261 LYS A CG  1 
ATOM   1947 C  CD  . LYS A 1 261 ? 122.552 92.923  120.268 1.00 66.48  ? 261 LYS A CD  1 
ATOM   1948 C  CE  . LYS A 1 261 ? 123.985 93.170  119.812 1.00 63.38  ? 261 LYS A CE  1 
ATOM   1949 N  NZ  . LYS A 1 261 ? 124.986 92.840  120.864 1.00 63.99  ? 261 LYS A NZ  1 
ATOM   1950 N  N   . ARG A 1 262 ? 119.546 96.599  121.897 1.00 56.88  ? 262 ARG A N   1 
ATOM   1951 C  CA  . ARG A 1 262 ? 119.680 98.016  121.575 1.00 53.12  ? 262 ARG A CA  1 
ATOM   1952 C  C   . ARG A 1 262 ? 119.488 98.888  122.807 1.00 54.73  ? 262 ARG A C   1 
ATOM   1953 O  O   . ARG A 1 262 ? 120.189 99.891  122.977 1.00 58.94  ? 262 ARG A O   1 
ATOM   1954 C  CB  . ARG A 1 262 ? 118.686 98.408  120.489 1.00 53.89  ? 262 ARG A CB  1 
ATOM   1955 C  CG  . ARG A 1 262 ? 118.775 99.863  120.078 1.00 52.22  ? 262 ARG A CG  1 
ATOM   1956 C  CD  . ARG A 1 262 ? 120.195 100.244 119.716 1.00 55.22  ? 262 ARG A CD  1 
ATOM   1957 N  NE  . ARG A 1 262 ? 120.310 101.656 119.380 1.00 58.14  ? 262 ARG A NE  1 
ATOM   1958 C  CZ  . ARG A 1 262 ? 120.365 102.636 120.270 1.00 54.38  ? 262 ARG A CZ  1 
ATOM   1959 N  NH1 . ARG A 1 262 ? 120.310 102.394 121.568 1.00 53.85  ? 262 ARG A NH1 1 
ATOM   1960 N  NH2 . ARG A 1 262 ? 120.480 103.889 119.847 1.00 50.64  ? 262 ARG A NH2 1 
ATOM   1961 N  N   . ALA A 1 263 ? 118.535 98.535  123.670 1.00 54.14  ? 263 ALA A N   1 
ATOM   1962 C  CA  . ALA A 1 263 ? 118.338 99.297  124.896 1.00 53.57  ? 263 ALA A CA  1 
ATOM   1963 C  C   . ALA A 1 263 ? 119.563 99.221  125.795 1.00 54.17  ? 263 ALA A C   1 
ATOM   1964 O  O   . ALA A 1 263 ? 120.005 100.237 126.342 1.00 58.51  ? 263 ALA A O   1 
ATOM   1965 C  CB  . ALA A 1 263 ? 117.102 98.791  125.634 1.00 55.27  ? 263 ALA A CB  1 
ATOM   1966 N  N   . VAL A 1 264 ? 120.127 98.024  125.958 1.00 50.31  ? 264 VAL A N   1 
ATOM   1967 C  CA  . VAL A 1 264 ? 121.306 97.865  126.803 1.00 47.78  ? 264 VAL A CA  1 
ATOM   1968 C  C   . VAL A 1 264 ? 122.518 98.531  126.165 1.00 48.54  ? 264 VAL A C   1 
ATOM   1969 O  O   . VAL A 1 264 ? 123.345 99.136  126.856 1.00 47.67  ? 264 VAL A O   1 
ATOM   1970 C  CB  . VAL A 1 264 ? 121.553 96.373  127.086 1.00 48.49  ? 264 VAL A CB  1 
ATOM   1971 C  CG1 . VAL A 1 264 ? 122.889 96.170  127.763 1.00 51.61  ? 264 VAL A CG1 1 
ATOM   1972 C  CG2 . VAL A 1 264 ? 120.442 95.815  127.947 1.00 50.61  ? 264 VAL A CG2 1 
ATOM   1973 N  N   . LEU A 1 265 ? 122.635 98.450  124.838 1.00 51.83  ? 265 LEU A N   1 
ATOM   1974 C  CA  . LEU A 1 265 ? 123.786 99.012  124.142 1.00 49.94  ? 265 LEU A CA  1 
ATOM   1975 C  C   . LEU A 1 265 ? 123.813 100.532 124.169 1.00 48.63  ? 265 LEU A C   1 
ATOM   1976 O  O   . LEU A 1 265 ? 124.818 101.119 123.757 1.00 49.58  ? 265 LEU A O   1 
ATOM   1977 C  CB  . LEU A 1 265 ? 123.820 98.534  122.691 1.00 47.10  ? 265 LEU A CB  1 
ATOM   1978 C  CG  . LEU A 1 265 ? 124.471 97.181  122.405 1.00 44.40  ? 265 LEU A CG  1 
ATOM   1979 C  CD1 . LEU A 1 265 ? 124.592 96.974  120.911 1.00 47.44  ? 265 LEU A CD1 1 
ATOM   1980 C  CD2 . LEU A 1 265 ? 125.825 97.081  123.070 1.00 48.06  ? 265 LEU A CD2 1 
ATOM   1981 N  N   . GLN A 1 266 ? 122.741 101.183 124.620 1.00 43.94  ? 266 GLN A N   1 
ATOM   1982 C  CA  . GLN A 1 266 ? 122.758 102.634 124.753 1.00 44.28  ? 266 GLN A CA  1 
ATOM   1983 C  C   . GLN A 1 266 ? 123.737 103.105 125.820 1.00 44.80  ? 266 GLN A C   1 
ATOM   1984 O  O   . GLN A 1 266 ? 124.231 104.233 125.738 1.00 45.53  ? 266 GLN A O   1 
ATOM   1985 C  CB  . GLN A 1 266 ? 121.353 103.145 125.068 1.00 41.27  ? 266 GLN A CB  1 
ATOM   1986 C  CG  . GLN A 1 266 ? 121.254 104.644 125.223 1.00 43.25  ? 266 GLN A CG  1 
ATOM   1987 C  CD  . GLN A 1 266 ? 121.325 105.368 123.904 1.00 44.86  ? 266 GLN A CD  1 
ATOM   1988 O  OE1 . GLN A 1 266 ? 121.325 104.748 122.845 1.00 46.30  ? 266 GLN A OE1 1 
ATOM   1989 N  NE2 . GLN A 1 266 ? 121.380 106.690 123.958 1.00 42.56  ? 266 GLN A NE2 1 
ATOM   1990 N  N   . PHE A 1 267 ? 124.043 102.267 126.807 1.00 43.78  ? 267 PHE A N   1 
ATOM   1991 C  CA  . PHE A 1 267 ? 124.965 102.624 127.874 1.00 41.26  ? 267 PHE A CA  1 
ATOM   1992 C  C   . PHE A 1 267 ? 126.411 102.283 127.540 1.00 44.08  ? 267 PHE A C   1 
ATOM   1993 O  O   . PHE A 1 267 ? 127.229 102.130 128.452 1.00 43.50  ? 267 PHE A O   1 
ATOM   1994 C  CB  . PHE A 1 267 ? 124.537 101.948 129.176 1.00 40.08  ? 267 PHE A CB  1 
ATOM   1995 C  CG  . PHE A 1 267 ? 123.225 102.445 129.695 1.00 40.84  ? 267 PHE A CG  1 
ATOM   1996 C  CD1 . PHE A 1 267 ? 122.040 101.874 129.276 1.00 44.24  ? 267 PHE A CD1 1 
ATOM   1997 C  CD2 . PHE A 1 267 ? 123.172 103.505 130.575 1.00 44.28  ? 267 PHE A CD2 1 
ATOM   1998 C  CE1 . PHE A 1 267 ? 120.833 102.340 129.737 1.00 45.75  ? 267 PHE A CE1 1 
ATOM   1999 C  CE2 . PHE A 1 267 ? 121.969 103.974 131.036 1.00 46.53  ? 267 PHE A CE2 1 
ATOM   2000 C  CZ  . PHE A 1 267 ? 120.798 103.390 130.618 1.00 45.46  ? 267 PHE A CZ  1 
ATOM   2001 N  N   . THR A 1 268 ? 126.739 102.165 126.259 1.00 37.97  ? 268 THR A N   1 
ATOM   2002 C  CA  . THR A 1 268 ? 128.079 101.904 125.765 1.00 40.77  ? 268 THR A CA  1 
ATOM   2003 C  C   . THR A 1 268 ? 128.461 102.987 124.764 1.00 42.73  ? 268 THR A C   1 
ATOM   2004 O  O   . THR A 1 268 ? 127.585 103.619 124.165 1.00 47.74  ? 268 THR A O   1 
ATOM   2005 C  CB  . THR A 1 268 ? 128.162 100.522 125.099 1.00 39.44  ? 268 THR A CB  1 
ATOM   2006 O  OG1 . THR A 1 268 ? 127.482 100.552 123.841 1.00 41.53  ? 268 THR A OG1 1 
ATOM   2007 C  CG2 . THR A 1 268 ? 127.535 99.464  125.983 1.00 35.21  ? 268 THR A CG2 1 
ATOM   2008 N  N   . PRO A 1 269 ? 129.756 103.246 124.572 1.00 38.72  ? 269 PRO A N   1 
ATOM   2009 C  CA  . PRO A 1 269 ? 130.158 104.340 123.680 1.00 36.64  ? 269 PRO A CA  1 
ATOM   2010 C  C   . PRO A 1 269 ? 129.653 104.141 122.261 1.00 42.75  ? 269 PRO A C   1 
ATOM   2011 O  O   . PRO A 1 269 ? 129.656 103.030 121.730 1.00 47.44  ? 269 PRO A O   1 
ATOM   2012 C  CB  . PRO A 1 269 ? 131.689 104.300 123.737 1.00 37.58  ? 269 PRO A CB  1 
ATOM   2013 C  CG  . PRO A 1 269 ? 132.027 102.971 124.295 1.00 39.50  ? 269 PRO A CG  1 
ATOM   2014 C  CD  . PRO A 1 269 ? 130.920 102.625 125.220 1.00 39.89  ? 269 PRO A CD  1 
ATOM   2015 N  N   . ALA A 1 270 ? 129.218 105.240 121.646 1.00 41.85  ? 270 ALA A N   1 
ATOM   2016 C  CA  . ALA A 1 270 ? 128.766 105.222 120.263 1.00 38.94  ? 270 ALA A CA  1 
ATOM   2017 C  C   . ALA A 1 270 ? 129.911 105.322 119.266 1.00 47.28  ? 270 ALA A C   1 
ATOM   2018 O  O   . ALA A 1 270 ? 129.700 105.063 118.078 1.00 51.80  ? 270 ALA A O   1 
ATOM   2019 C  CB  . ALA A 1 270 ? 127.778 106.361 120.019 1.00 37.78  ? 270 ALA A CB  1 
ATOM   2020 N  N   . SER A 1 271 ? 131.104 105.691 119.719 1.00 46.18  ? 271 SER A N   1 
ATOM   2021 C  CA  . SER A 1 271 ? 132.283 105.753 118.869 1.00 42.44  ? 271 SER A CA  1 
ATOM   2022 C  C   . SER A 1 271 ? 133.506 105.788 119.768 1.00 43.73  ? 271 SER A C   1 
ATOM   2023 O  O   . SER A 1 271 ? 133.409 106.076 120.962 1.00 40.95  ? 271 SER A O   1 
ATOM   2024 C  CB  . SER A 1 271 ? 132.248 106.970 117.944 1.00 42.87  ? 271 SER A CB  1 
ATOM   2025 O  OG  . SER A 1 271 ? 131.870 108.133 118.656 1.00 49.99  ? 271 SER A OG  1 
ATOM   2026 N  N   . TRP A 1 272 ? 134.662 105.488 119.185 1.00 49.69  ? 272 TRP A N   1 
ATOM   2027 C  CA  . TRP A 1 272 ? 135.909 105.441 119.938 1.00 49.81  ? 272 TRP A CA  1 
ATOM   2028 C  C   . TRP A 1 272 ? 136.985 106.209 119.192 1.00 51.65  ? 272 TRP A C   1 
ATOM   2029 O  O   . TRP A 1 272 ? 137.243 105.939 118.015 1.00 54.11  ? 272 TRP A O   1 
ATOM   2030 C  CB  . TRP A 1 272 ? 136.354 104.001 120.185 1.00 46.88  ? 272 TRP A CB  1 
ATOM   2031 C  CG  . TRP A 1 272 ? 137.054 103.836 121.486 1.00 48.27  ? 272 TRP A CG  1 
ATOM   2032 C  CD1 . TRP A 1 272 ? 138.329 103.405 121.678 1.00 52.42  ? 272 TRP A CD1 1 
ATOM   2033 C  CD2 . TRP A 1 272 ? 136.523 104.112 122.785 1.00 48.19  ? 272 TRP A CD2 1 
ATOM   2034 N  NE1 . TRP A 1 272 ? 138.625 103.390 123.016 1.00 51.52  ? 272 TRP A NE1 1 
ATOM   2035 C  CE2 . TRP A 1 272 ? 137.529 103.819 123.717 1.00 47.66  ? 272 TRP A CE2 1 
ATOM   2036 C  CE3 . TRP A 1 272 ? 135.290 104.572 123.250 1.00 44.96  ? 272 TRP A CE3 1 
ATOM   2037 C  CZ2 . TRP A 1 272 ? 137.344 103.974 125.083 1.00 48.82  ? 272 TRP A CZ2 1 
ATOM   2038 C  CZ3 . TRP A 1 272 ? 135.110 104.726 124.604 1.00 47.57  ? 272 TRP A CZ3 1 
ATOM   2039 C  CH2 . TRP A 1 272 ? 136.130 104.428 125.506 1.00 50.26  ? 272 TRP A CH2 1 
ATOM   2040 N  N   . THR A 1 273 ? 137.608 107.158 119.880 1.00 54.50  ? 273 THR A N   1 
ATOM   2041 C  CA  . THR A 1 273 ? 138.687 107.942 119.308 1.00 52.15  ? 273 THR A CA  1 
ATOM   2042 C  C   . THR A 1 273 ? 139.979 107.139 119.306 1.00 53.69  ? 273 THR A C   1 
ATOM   2043 O  O   . THR A 1 273 ? 140.262 106.388 120.242 1.00 57.42  ? 273 THR A O   1 
ATOM   2044 C  CB  . THR A 1 273 ? 138.874 109.231 120.106 1.00 53.36  ? 273 THR A CB  1 
ATOM   2045 O  OG1 . THR A 1 273 ? 137.605 109.871 120.270 1.00 52.29  ? 273 THR A OG1 1 
ATOM   2046 C  CG2 . THR A 1 273 ? 139.814 110.178 119.384 1.00 52.84  ? 273 THR A CG2 1 
ATOM   2047 N  N   . TYR A 1 274 ? 140.763 107.296 118.245 1.00 58.71  ? 274 TYR A N   1 
ATOM   2048 C  CA  . TYR A 1 274 ? 142.071 106.661 118.146 1.00 59.73  ? 274 TYR A CA  1 
ATOM   2049 C  C   . TYR A 1 274 ? 143.087 107.569 118.829 1.00 62.55  ? 274 TYR A C   1 
ATOM   2050 O  O   . TYR A 1 274 ? 143.333 108.689 118.373 1.00 66.60  ? 274 TYR A O   1 
ATOM   2051 C  CB  . TYR A 1 274 ? 142.434 106.408 116.687 1.00 59.64  ? 274 TYR A CB  1 
ATOM   2052 C  CG  . TYR A 1 274 ? 143.710 105.626 116.494 1.00 62.93  ? 274 TYR A CG  1 
ATOM   2053 C  CD1 . TYR A 1 274 ? 143.957 104.471 117.221 1.00 63.00  ? 274 TYR A CD1 1 
ATOM   2054 C  CD2 . TYR A 1 274 ? 144.665 106.038 115.579 1.00 62.19  ? 274 TYR A CD2 1 
ATOM   2055 C  CE1 . TYR A 1 274 ? 145.122 103.753 117.048 1.00 62.30  ? 274 TYR A CE1 1 
ATOM   2056 C  CE2 . TYR A 1 274 ? 145.831 105.325 115.396 1.00 63.18  ? 274 TYR A CE2 1 
ATOM   2057 C  CZ  . TYR A 1 274 ? 146.056 104.185 116.133 1.00 64.18  ? 274 TYR A CZ  1 
ATOM   2058 O  OH  . TYR A 1 274 ? 147.219 103.472 115.953 1.00 64.91  ? 274 TYR A OH  1 
ATOM   2059 N  N   . VAL A 1 275 ? 143.676 107.086 119.919 1.00 48.28  ? 275 VAL A N   1 
ATOM   2060 C  CA  . VAL A 1 275 ? 144.535 107.890 120.780 1.00 46.43  ? 275 VAL A CA  1 
ATOM   2061 C  C   . VAL A 1 275 ? 145.991 107.610 120.441 1.00 53.00  ? 275 VAL A C   1 
ATOM   2062 O  O   . VAL A 1 275 ? 146.426 106.452 120.435 1.00 54.96  ? 275 VAL A O   1 
ATOM   2063 C  CB  . VAL A 1 275 ? 144.254 107.603 122.263 1.00 42.87  ? 275 VAL A CB  1 
ATOM   2064 C  CG1 . VAL A 1 275 ? 144.930 108.625 123.135 1.00 45.33  ? 275 VAL A CG1 1 
ATOM   2065 C  CG2 . VAL A 1 275 ? 142.771 107.610 122.518 1.00 46.44  ? 275 VAL A CG2 1 
ATOM   2066 N  N   . ARG A 1 276 ? 146.744 108.671 120.157 1.00 53.69  ? 276 ARG A N   1 
ATOM   2067 C  CA  . ARG A 1 276 ? 148.184 108.586 119.913 1.00 50.18  ? 276 ARG A CA  1 
ATOM   2068 C  C   . ARG A 1 276 ? 148.828 109.732 120.683 1.00 53.91  ? 276 ARG A C   1 
ATOM   2069 O  O   . ARG A 1 276 ? 148.863 110.866 120.198 1.00 58.20  ? 276 ARG A O   1 
ATOM   2070 C  CB  . ARG A 1 276 ? 148.514 108.675 118.429 1.00 54.94  ? 276 ARG A CB  1 
ATOM   2071 C  CG  . ARG A 1 276 ? 148.019 107.517 117.592 1.00 52.13  ? 276 ARG A CG  1 
ATOM   2072 C  CD  . ARG A 1 276 ? 147.941 107.916 116.128 1.00 56.76  ? 276 ARG A CD  1 
ATOM   2073 N  NE  . ARG A 1 276 ? 146.726 108.665 115.834 1.00 62.40  ? 276 ARG A NE  1 
ATOM   2074 C  CZ  . ARG A 1 276 ? 146.600 109.527 114.834 1.00 63.47  ? 276 ARG A CZ  1 
ATOM   2075 N  NH1 . ARG A 1 276 ? 147.598 109.772 114.002 1.00 59.19  ? 276 ARG A NH1 1 
ATOM   2076 N  NH2 . ARG A 1 276 ? 145.441 110.157 114.663 1.00 59.31  ? 276 ARG A NH2 1 
ATOM   2077 N  N   . TRP A 1 277 ? 149.329 109.439 121.881 1.00 44.83  ? 277 TRP A N   1 
ATOM   2078 C  CA  . TRP A 1 277 ? 149.919 110.492 122.698 1.00 43.72  ? 277 TRP A CA  1 
ATOM   2079 C  C   . TRP A 1 277 ? 151.229 110.993 122.110 1.00 43.37  ? 277 TRP A C   1 
ATOM   2080 O  O   . TRP A 1 277 ? 151.534 112.186 122.212 1.00 45.87  ? 277 TRP A O   1 
ATOM   2081 C  CB  . TRP A 1 277 ? 150.128 109.992 124.126 1.00 39.22  ? 277 TRP A CB  1 
ATOM   2082 C  CG  . TRP A 1 277 ? 148.847 109.752 124.848 1.00 38.76  ? 277 TRP A CG  1 
ATOM   2083 C  CD1 . TRP A 1 277 ? 148.193 108.568 124.978 1.00 35.43  ? 277 TRP A CD1 1 
ATOM   2084 C  CD2 . TRP A 1 277 ? 148.053 110.726 125.531 1.00 37.36  ? 277 TRP A CD2 1 
ATOM   2085 N  NE1 . TRP A 1 277 ? 147.043 108.740 125.701 1.00 36.90  ? 277 TRP A NE1 1 
ATOM   2086 C  CE2 . TRP A 1 277 ? 146.934 110.059 126.052 1.00 36.06  ? 277 TRP A CE2 1 
ATOM   2087 C  CE3 . TRP A 1 277 ? 148.180 112.100 125.750 1.00 38.45  ? 277 TRP A CE3 1 
ATOM   2088 C  CZ2 . TRP A 1 277 ? 145.951 110.715 126.781 1.00 38.48  ? 277 TRP A CZ2 1 
ATOM   2089 C  CZ3 . TRP A 1 277 ? 147.205 112.745 126.474 1.00 35.89  ? 277 TRP A CZ3 1 
ATOM   2090 C  CH2 . TRP A 1 277 ? 146.104 112.055 126.980 1.00 34.54  ? 277 TRP A CH2 1 
ATOM   2091 N  N   . PHE A 1 278 ? 152.004 110.114 121.484 1.00 64.59  ? 278 PHE A N   1 
ATOM   2092 C  CA  . PHE A 1 278 ? 153.332 110.448 120.996 1.00 64.93  ? 278 PHE A CA  1 
ATOM   2093 C  C   . PHE A 1 278 ? 153.400 110.288 119.486 1.00 65.51  ? 278 PHE A C   1 
ATOM   2094 O  O   . PHE A 1 278 ? 152.756 109.411 118.905 1.00 64.55  ? 278 PHE A O   1 
ATOM   2095 C  CB  . PHE A 1 278 ? 154.401 109.561 121.640 1.00 65.03  ? 278 PHE A CB  1 
ATOM   2096 C  CG  . PHE A 1 278 ? 154.486 109.701 123.127 1.00 62.15  ? 278 PHE A CG  1 
ATOM   2097 C  CD1 . PHE A 1 278 ? 155.033 110.834 123.698 1.00 62.63  ? 278 PHE A CD1 1 
ATOM   2098 C  CD2 . PHE A 1 278 ? 154.030 108.692 123.953 1.00 62.65  ? 278 PHE A CD2 1 
ATOM   2099 C  CE1 . PHE A 1 278 ? 155.109 110.963 125.063 1.00 64.39  ? 278 PHE A CE1 1 
ATOM   2100 C  CE2 . PHE A 1 278 ? 154.105 108.814 125.318 1.00 65.65  ? 278 PHE A CE2 1 
ATOM   2101 C  CZ  . PHE A 1 278 ? 154.647 109.952 125.875 1.00 70.25  ? 278 PHE A CZ  1 
ATOM   2102 N  N   . ASP A 1 279 ? 154.198 111.142 118.860 1.00 81.57  ? 279 ASP A N   1 
ATOM   2103 C  CA  . ASP A 1 279 ? 154.510 111.058 117.445 1.00 85.97  ? 279 ASP A CA  1 
ATOM   2104 C  C   . ASP A 1 279 ? 156.018 111.120 117.262 1.00 87.42  ? 279 ASP A C   1 
ATOM   2105 O  O   . ASP A 1 279 ? 156.722 111.708 118.089 1.00 83.64  ? 279 ASP A O   1 
ATOM   2106 C  CB  . ASP A 1 279 ? 153.849 112.197 116.656 1.00 84.49  ? 279 ASP A CB  1 
ATOM   2107 C  CG  . ASP A 1 279 ? 152.346 112.059 116.585 1.00 83.34  ? 279 ASP A CG  1 
ATOM   2108 O  OD1 . ASP A 1 279 ? 151.864 111.008 116.117 1.00 85.39  ? 279 ASP A OD1 1 
ATOM   2109 O  OD2 . ASP A 1 279 ? 151.644 113.005 116.992 1.00 81.94  ? 279 ASP A OD2 1 
ATOM   2110 N  N   . PRO A 1 280 ? 156.546 110.504 116.201 1.00 98.39  ? 280 PRO A N   1 
ATOM   2111 C  CA  . PRO A 1 280 ? 157.990 110.617 115.947 1.00 98.35  ? 280 PRO A CA  1 
ATOM   2112 C  C   . PRO A 1 280 ? 158.440 112.048 115.724 1.00 97.91  ? 280 PRO A C   1 
ATOM   2113 O  O   . PRO A 1 280 ? 159.571 112.400 116.081 1.00 96.46  ? 280 PRO A O   1 
ATOM   2114 C  CB  . PRO A 1 280 ? 158.196 109.752 114.696 1.00 95.95  ? 280 PRO A CB  1 
ATOM   2115 C  CG  . PRO A 1 280 ? 157.012 108.841 114.659 1.00 96.98  ? 280 PRO A CG  1 
ATOM   2116 C  CD  . PRO A 1 280 ? 155.878 109.643 115.212 1.00 95.56  ? 280 PRO A CD  1 
ATOM   2117 N  N   . LYS A 1 281 ? 157.584 112.885 115.143 1.00 94.91  ? 281 LYS A N   1 
ATOM   2118 C  CA  . LYS A 1 281 ? 157.884 114.288 114.906 1.00 94.25  ? 281 LYS A CA  1 
ATOM   2119 C  C   . LYS A 1 281 ? 157.294 115.197 115.973 1.00 95.72  ? 281 LYS A C   1 
ATOM   2120 O  O   . LYS A 1 281 ? 157.239 116.415 115.772 1.00 98.04  ? 281 LYS A O   1 
ATOM   2121 C  CB  . LYS A 1 281 ? 157.374 114.710 113.528 1.00 96.03  ? 281 LYS A CB  1 
ATOM   2122 C  CG  . LYS A 1 281 ? 157.861 113.842 112.378 1.00 96.72  ? 281 LYS A CG  1 
ATOM   2123 C  CD  . LYS A 1 281 ? 159.372 113.892 112.242 1.00 95.98  ? 281 LYS A CD  1 
ATOM   2124 C  CE  . LYS A 1 281 ? 159.839 113.114 111.025 1.00 96.09  ? 281 LYS A CE  1 
ATOM   2125 N  NZ  . LYS A 1 281 ? 159.333 111.715 111.035 1.00 98.03  ? 281 LYS A NZ  1 
ATOM   2126 N  N   . SER A 1 282 ? 156.841 114.634 117.092 1.00 88.80  ? 282 SER A N   1 
ATOM   2127 C  CA  . SER A 1 282 ? 156.190 115.423 118.131 1.00 87.61  ? 282 SER A CA  1 
ATOM   2128 C  C   . SER A 1 282 ? 157.140 116.474 118.690 1.00 84.80  ? 282 SER A C   1 
ATOM   2129 O  O   . SER A 1 282 ? 158.304 116.189 118.981 1.00 81.67  ? 282 SER A O   1 
ATOM   2130 C  CB  . SER A 1 282 ? 155.692 114.508 119.247 1.00 86.16  ? 282 SER A CB  1 
ATOM   2131 O  OG  . SER A 1 282 ? 156.665 113.534 119.573 1.00 86.20  ? 282 SER A OG  1 
ATOM   2132 N  N   . SER A 1 283 ? 156.630 117.689 118.849 1.00 76.08  ? 283 SER A N   1 
ATOM   2133 C  CA  . SER A 1 283 ? 157.443 118.828 119.247 1.00 77.94  ? 283 SER A CA  1 
ATOM   2134 C  C   . SER A 1 283 ? 157.764 118.751 120.738 1.00 77.42  ? 283 SER A C   1 
ATOM   2135 O  O   . SER A 1 283 ? 157.470 117.764 121.417 1.00 76.16  ? 283 SER A O   1 
ATOM   2136 C  CB  . SER A 1 283 ? 156.729 120.128 118.891 1.00 75.96  ? 283 SER A CB  1 
ATOM   2137 O  OG  . SER A 1 283 ? 155.352 120.052 119.215 1.00 75.23  ? 283 SER A OG  1 
ATOM   2138 N  N   . PHE A 1 284 ? 158.395 119.803 121.260 1.00 70.88  ? 284 PHE A N   1 
ATOM   2139 C  CA  . PHE A 1 284 ? 158.623 119.889 122.697 1.00 66.31  ? 284 PHE A CA  1 
ATOM   2140 C  C   . PHE A 1 284 ? 157.331 120.209 123.432 1.00 68.56  ? 284 PHE A C   1 
ATOM   2141 O  O   . PHE A 1 284 ? 157.159 119.813 124.591 1.00 74.41  ? 284 PHE A O   1 
ATOM   2142 C  CB  . PHE A 1 284 ? 159.679 120.951 123.005 1.00 68.55  ? 284 PHE A CB  1 
ATOM   2143 C  CG  . PHE A 1 284 ? 161.079 120.569 122.593 1.00 75.97  ? 284 PHE A CG  1 
ATOM   2144 C  CD1 . PHE A 1 284 ? 161.317 119.457 121.802 1.00 75.49  ? 284 PHE A CD1 1 
ATOM   2145 C  CD2 . PHE A 1 284 ? 162.159 121.340 122.991 1.00 75.08  ? 284 PHE A CD2 1 
ATOM   2146 C  CE1 . PHE A 1 284 ? 162.601 119.117 121.423 1.00 71.67  ? 284 PHE A CE1 1 
ATOM   2147 C  CE2 . PHE A 1 284 ? 163.446 121.005 122.615 1.00 73.94  ? 284 PHE A CE2 1 
ATOM   2148 C  CZ  . PHE A 1 284 ? 163.667 119.892 121.831 1.00 72.68  ? 284 PHE A CZ  1 
ATOM   2149 N  N   . GLN A 1 285 ? 156.417 120.923 122.773 1.00 58.74  ? 285 GLN A N   1 
ATOM   2150 C  CA  . GLN A 1 285 ? 155.141 121.258 123.390 1.00 54.59  ? 285 GLN A CA  1 
ATOM   2151 C  C   . GLN A 1 285 ? 154.333 120.006 123.699 1.00 59.77  ? 285 GLN A C   1 
ATOM   2152 O  O   . GLN A 1 285 ? 153.780 119.874 124.793 1.00 65.57  ? 285 GLN A O   1 
ATOM   2153 C  CB  . GLN A 1 285 ? 154.352 122.187 122.471 1.00 58.42  ? 285 GLN A CB  1 
ATOM   2154 C  CG  . GLN A 1 285 ? 154.847 123.619 122.457 1.00 61.51  ? 285 GLN A CG  1 
ATOM   2155 C  CD  . GLN A 1 285 ? 154.091 124.503 123.424 1.00 66.44  ? 285 GLN A CD  1 
ATOM   2156 O  OE1 . GLN A 1 285 ? 154.093 124.266 124.630 1.00 65.78  ? 285 GLN A OE1 1 
ATOM   2157 N  NE2 . GLN A 1 285 ? 153.432 125.528 122.897 1.00 62.50  ? 285 GLN A NE2 1 
ATOM   2158 N  N   . ARG A 1 286 ? 154.261 119.069 122.754 1.00 56.69  ? 286 ARG A N   1 
ATOM   2159 C  CA  . ARG A 1 286 ? 153.487 117.852 122.977 1.00 50.83  ? 286 ARG A CA  1 
ATOM   2160 C  C   . ARG A 1 286 ? 154.109 116.990 124.065 1.00 50.04  ? 286 ARG A C   1 
ATOM   2161 O  O   . ARG A 1 286 ? 153.398 116.421 124.904 1.00 58.42  ? 286 ARG A O   1 
ATOM   2162 C  CB  . ARG A 1 286 ? 153.373 117.069 121.674 1.00 49.17  ? 286 ARG A CB  1 
ATOM   2163 C  CG  . ARG A 1 286 ? 152.417 115.906 121.727 1.00 48.74  ? 286 ARG A CG  1 
ATOM   2164 C  CD  . ARG A 1 286 ? 151.474 115.949 120.546 1.00 53.73  ? 286 ARG A CD  1 
ATOM   2165 N  NE  . ARG A 1 286 ? 150.864 114.654 120.282 1.00 52.23  ? 286 ARG A NE  1 
ATOM   2166 C  CZ  . ARG A 1 286 ? 150.145 114.379 119.205 1.00 57.34  ? 286 ARG A CZ  1 
ATOM   2167 N  NH1 . ARG A 1 286 ? 149.915 115.291 118.276 1.00 57.65  ? 286 ARG A NH1 1 
ATOM   2168 N  NH2 . ARG A 1 286 ? 149.650 113.156 119.052 1.00 55.94  ? 286 ARG A NH2 1 
ATOM   2169 N  N   . VAL A 1 287 ? 155.437 116.874 124.061 1.00 50.09  ? 287 VAL A N   1 
ATOM   2170 C  CA  . VAL A 1 287 ? 156.121 116.072 125.068 1.00 47.53  ? 287 VAL A CA  1 
ATOM   2171 C  C   . VAL A 1 287 ? 155.897 116.661 126.451 1.00 46.91  ? 287 VAL A C   1 
ATOM   2172 O  O   . VAL A 1 287 ? 155.596 115.940 127.411 1.00 55.47  ? 287 VAL A O   1 
ATOM   2173 C  CB  . VAL A 1 287 ? 157.616 115.970 124.723 1.00 54.59  ? 287 VAL A CB  1 
ATOM   2174 C  CG1 . VAL A 1 287 ? 158.453 115.769 125.976 1.00 52.74  ? 287 VAL A CG1 1 
ATOM   2175 C  CG2 . VAL A 1 287 ? 157.841 114.870 123.715 1.00 54.07  ? 287 VAL A CG2 1 
ATOM   2176 N  N   . ALA A 1 288 ? 156.016 117.984 126.573 1.00 39.27  ? 288 ALA A N   1 
ATOM   2177 C  CA  . ALA A 1 288 ? 155.749 118.626 127.852 1.00 35.67  ? 288 ALA A CA  1 
ATOM   2178 C  C   . ALA A 1 288 ? 154.278 118.526 128.238 1.00 39.92  ? 288 ALA A C   1 
ATOM   2179 O  O   . ALA A 1 288 ? 153.956 118.489 129.427 1.00 51.67  ? 288 ALA A O   1 
ATOM   2180 C  CB  . ALA A 1 288 ? 156.197 120.083 127.809 1.00 39.70  ? 288 ALA A CB  1 
ATOM   2181 N  N   . GLY A 1 289 ? 153.374 118.471 127.261 1.00 32.06  ? 289 GLY A N   1 
ATOM   2182 C  CA  . GLY A 1 289 ? 151.971 118.277 127.583 1.00 31.93  ? 289 GLY A CA  1 
ATOM   2183 C  C   . GLY A 1 289 ? 151.692 116.912 128.177 1.00 39.80  ? 289 GLY A C   1 
ATOM   2184 O  O   . GLY A 1 289 ? 150.939 116.791 129.144 1.00 47.77  ? 289 GLY A O   1 
ATOM   2185 N  N   . VAL A 1 290 ? 152.295 115.868 127.611 1.00 41.56  ? 290 VAL A N   1 
ATOM   2186 C  CA  . VAL A 1 290 ? 152.163 114.536 128.200 1.00 33.55  ? 290 VAL A CA  1 
ATOM   2187 C  C   . VAL A 1 290 ? 152.828 114.491 129.572 1.00 40.33  ? 290 VAL A C   1 
ATOM   2188 O  O   . VAL A 1 290 ? 152.340 113.830 130.500 1.00 52.79  ? 290 VAL A O   1 
ATOM   2189 C  CB  . VAL A 1 290 ? 152.740 113.469 127.255 1.00 36.38  ? 290 VAL A CB  1 
ATOM   2190 C  CG1 . VAL A 1 290 ? 152.417 112.090 127.772 1.00 42.41  ? 290 VAL A CG1 1 
ATOM   2191 C  CG2 . VAL A 1 290 ? 152.177 113.644 125.868 1.00 38.19  ? 290 VAL A CG2 1 
ATOM   2192 N  N   . TYR A 1 291 ? 153.950 115.195 129.724 1.00 37.11  ? 291 TYR A N   1 
ATOM   2193 C  CA  . TYR A 1 291 ? 154.619 115.262 131.019 1.00 39.54  ? 291 TYR A CA  1 
ATOM   2194 C  C   . TYR A 1 291 ? 153.718 115.890 132.076 1.00 41.25  ? 291 TYR A C   1 
ATOM   2195 O  O   . TYR A 1 291 ? 153.592 115.371 133.192 1.00 47.76  ? 291 TYR A O   1 
ATOM   2196 C  CB  . TYR A 1 291 ? 155.918 116.052 130.878 1.00 38.95  ? 291 TYR A CB  1 
ATOM   2197 C  CG  . TYR A 1 291 ? 156.789 116.036 132.102 1.00 41.03  ? 291 TYR A CG  1 
ATOM   2198 C  CD1 . TYR A 1 291 ? 157.268 114.846 132.614 1.00 46.87  ? 291 TYR A CD1 1 
ATOM   2199 C  CD2 . TYR A 1 291 ? 157.143 117.211 132.740 1.00 41.94  ? 291 TYR A CD2 1 
ATOM   2200 C  CE1 . TYR A 1 291 ? 158.069 114.824 133.725 1.00 46.06  ? 291 TYR A CE1 1 
ATOM   2201 C  CE2 . TYR A 1 291 ? 157.945 117.197 133.855 1.00 44.13  ? 291 TYR A CE2 1 
ATOM   2202 C  CZ  . TYR A 1 291 ? 158.402 115.999 134.344 1.00 46.70  ? 291 TYR A CZ  1 
ATOM   2203 O  OH  . TYR A 1 291 ? 159.208 115.966 135.453 1.00 48.44  ? 291 TYR A OH  1 
ATOM   2204 N  N   . LEU A 1 292 ? 153.079 117.009 131.740 1.00 30.98  ? 292 LEU A N   1 
ATOM   2205 C  CA  . LEU A 1 292 ? 152.148 117.642 132.666 1.00 27.53  ? 292 LEU A CA  1 
ATOM   2206 C  C   . LEU A 1 292 ? 150.944 116.750 132.930 1.00 33.46  ? 292 LEU A C   1 
ATOM   2207 O  O   . LEU A 1 292 ? 150.424 116.713 134.049 1.00 49.36  ? 292 LEU A O   1 
ATOM   2208 C  CB  . LEU A 1 292 ? 151.702 118.993 132.116 1.00 36.24  ? 292 LEU A CB  1 
ATOM   2209 C  CG  . LEU A 1 292 ? 150.543 119.678 132.833 1.00 36.03  ? 292 LEU A CG  1 
ATOM   2210 C  CD1 . LEU A 1 292 ? 150.971 120.128 134.213 1.00 39.53  ? 292 LEU A CD1 1 
ATOM   2211 C  CD2 . LEU A 1 292 ? 150.041 120.852 132.019 1.00 37.30  ? 292 LEU A CD2 1 
ATOM   2212 N  N   . PHE A 1 293 ? 150.482 116.030 131.908 1.00 27.26  ? 293 PHE A N   1 
ATOM   2213 C  CA  . PHE A 1 293 ? 149.379 115.097 132.097 1.00 20.97  ? 293 PHE A CA  1 
ATOM   2214 C  C   . PHE A 1 293 ? 149.713 114.077 133.173 1.00 25.63  ? 293 PHE A C   1 
ATOM   2215 O  O   . PHE A 1 293 ? 148.929 113.853 134.101 1.00 42.62  ? 293 PHE A O   1 
ATOM   2216 C  CB  . PHE A 1 293 ? 149.063 114.399 130.776 1.00 29.33  ? 293 PHE A CB  1 
ATOM   2217 C  CG  . PHE A 1 293 ? 147.937 113.419 130.859 1.00 33.46  ? 293 PHE A CG  1 
ATOM   2218 C  CD1 . PHE A 1 293 ? 146.628 113.850 130.820 1.00 34.66  ? 293 PHE A CD1 1 
ATOM   2219 C  CD2 . PHE A 1 293 ? 148.186 112.067 130.962 1.00 29.04  ? 293 PHE A CD2 1 
ATOM   2220 C  CE1 . PHE A 1 293 ? 145.594 112.957 130.888 1.00 31.69  ? 293 PHE A CE1 1 
ATOM   2221 C  CE2 . PHE A 1 293 ? 147.154 111.171 131.035 1.00 28.60  ? 293 PHE A CE2 1 
ATOM   2222 C  CZ  . PHE A 1 293 ? 145.857 111.619 130.997 1.00 31.17  ? 293 PHE A CZ  1 
ATOM   2223 N  N   . MET A 1 294 ? 150.892 113.471 133.082 1.00 28.76  ? 294 MET A N   1 
ATOM   2224 C  CA  . MET A 1 294 ? 151.253 112.452 134.061 1.00 27.46  ? 294 MET A CA  1 
ATOM   2225 C  C   . MET A 1 294 ? 151.562 113.051 135.430 1.00 32.89  ? 294 MET A C   1 
ATOM   2226 O  O   . MET A 1 294 ? 151.298 112.414 136.459 1.00 36.44  ? 294 MET A O   1 
ATOM   2227 C  CB  . MET A 1 294 ? 152.424 111.630 133.540 1.00 30.82  ? 294 MET A CB  1 
ATOM   2228 C  CG  . MET A 1 294 ? 152.042 110.777 132.351 1.00 37.42  ? 294 MET A CG  1 
ATOM   2229 S  SD  . MET A 1 294 ? 153.348 109.648 131.880 1.00 61.02  ? 294 MET A SD  1 
ATOM   2230 C  CE  . MET A 1 294 ? 154.720 110.781 131.898 1.00 43.42  ? 294 MET A CE  1 
ATOM   2231 N  N   . ILE A 1 295 ? 152.088 114.276 135.474 1.00 39.43  ? 295 ILE A N   1 
ATOM   2232 C  CA  . ILE A 1 295 ? 152.305 114.937 136.760 1.00 37.07  ? 295 ILE A CA  1 
ATOM   2233 C  C   . ILE A 1 295 ? 150.978 115.176 137.471 1.00 36.68  ? 295 ILE A C   1 
ATOM   2234 O  O   . ILE A 1 295 ? 150.847 114.921 138.673 1.00 45.76  ? 295 ILE A O   1 
ATOM   2235 C  CB  . ILE A 1 295 ? 153.081 116.248 136.569 1.00 31.21  ? 295 ILE A CB  1 
ATOM   2236 C  CG1 . ILE A 1 295 ? 154.575 115.976 136.526 1.00 34.56  ? 295 ILE A CG1 1 
ATOM   2237 C  CG2 . ILE A 1 295 ? 152.775 117.216 137.687 1.00 32.82  ? 295 ILE A CG2 1 
ATOM   2238 C  CD1 . ILE A 1 295 ? 155.357 117.192 136.170 1.00 43.98  ? 295 ILE A CD1 1 
ATOM   2239 N  N   . ILE A 1 296 ? 149.974 115.673 136.747 1.00 28.07  ? 296 ILE A N   1 
ATOM   2240 C  CA  . ILE A 1 296 ? 148.670 115.886 137.370 1.00 24.94  ? 296 ILE A CA  1 
ATOM   2241 C  C   . ILE A 1 296 ? 148.031 114.553 137.742 1.00 29.84  ? 296 ILE A C   1 
ATOM   2242 O  O   . ILE A 1 296 ? 147.348 114.442 138.767 1.00 41.62  ? 296 ILE A O   1 
ATOM   2243 C  CB  . ILE A 1 296 ? 147.752 116.720 136.460 1.00 31.35  ? 296 ILE A CB  1 
ATOM   2244 C  CG1 . ILE A 1 296 ? 148.446 118.006 136.029 1.00 30.40  ? 296 ILE A CG1 1 
ATOM   2245 C  CG2 . ILE A 1 296 ? 146.472 117.073 137.190 1.00 36.30  ? 296 ILE A CG2 1 
ATOM   2246 C  CD1 . ILE A 1 296 ? 149.032 118.784 137.165 1.00 40.84  ? 296 ILE A CD1 1 
ATOM   2247 N  N   . TRP A 1 297 ? 148.246 113.520 136.926 1.00 29.27  ? 297 TRP A N   1 
ATOM   2248 C  CA  . TRP A 1 297 ? 147.726 112.197 137.255 1.00 32.06  ? 297 TRP A CA  1 
ATOM   2249 C  C   . TRP A 1 297 ? 148.274 111.717 138.594 1.00 36.16  ? 297 TRP A C   1 
ATOM   2250 O  O   . TRP A 1 297 ? 147.525 111.207 139.433 1.00 52.40  ? 297 TRP A O   1 
ATOM   2251 C  CB  . TRP A 1 297 ? 148.067 111.217 136.129 1.00 35.34  ? 297 TRP A CB  1 
ATOM   2252 C  CG  . TRP A 1 297 ? 147.536 109.811 136.275 1.00 34.83  ? 297 TRP A CG  1 
ATOM   2253 C  CD1 . TRP A 1 297 ? 147.006 109.235 137.390 1.00 34.60  ? 297 TRP A CD1 1 
ATOM   2254 C  CD2 . TRP A 1 297 ? 147.495 108.807 135.253 1.00 42.67  ? 297 TRP A CD2 1 
ATOM   2255 N  NE1 . TRP A 1 297 ? 146.642 107.940 137.131 1.00 41.00  ? 297 TRP A NE1 1 
ATOM   2256 C  CE2 . TRP A 1 297 ? 146.930 107.653 135.824 1.00 44.23  ? 297 TRP A CE2 1 
ATOM   2257 C  CE3 . TRP A 1 297 ? 147.878 108.774 133.910 1.00 39.94  ? 297 TRP A CE3 1 
ATOM   2258 C  CZ2 . TRP A 1 297 ? 146.743 106.481 135.102 1.00 42.60  ? 297 TRP A CZ2 1 
ATOM   2259 C  CZ3 . TRP A 1 297 ? 147.699 107.610 133.200 1.00 42.39  ? 297 TRP A CZ3 1 
ATOM   2260 C  CH2 . TRP A 1 297 ? 147.135 106.480 133.794 1.00 42.46  ? 297 TRP A CH2 1 
ATOM   2261 N  N   . GLN A 1 298 ? 149.576 111.882 138.823 1.00 36.20  ? 298 GLN A N   1 
ATOM   2262 C  CA  . GLN A 1 298 ? 150.142 111.441 140.096 1.00 35.94  ? 298 GLN A CA  1 
ATOM   2263 C  C   . GLN A 1 298 ? 149.789 112.376 141.247 1.00 40.65  ? 298 GLN A C   1 
ATOM   2264 O  O   . GLN A 1 298 ? 149.706 111.938 142.405 1.00 47.68  ? 298 GLN A O   1 
ATOM   2265 C  CB  . GLN A 1 298 ? 151.653 111.304 139.976 1.00 37.16  ? 298 GLN A CB  1 
ATOM   2266 C  CG  . GLN A 1 298 ? 152.076 110.371 138.873 1.00 45.23  ? 298 GLN A CG  1 
ATOM   2267 C  CD  . GLN A 1 298 ? 153.257 109.522 139.258 1.00 48.31  ? 298 GLN A CD  1 
ATOM   2268 O  OE1 . GLN A 1 298 ? 154.334 109.645 138.680 1.00 49.90  ? 298 GLN A OE1 1 
ATOM   2269 N  NE2 . GLN A 1 298 ? 153.068 108.655 140.245 1.00 42.30  ? 298 GLN A NE2 1 
ATOM   2270 N  N   . LEU A 1 299 ? 149.586 113.660 140.955 1.00 38.04  ? 299 LEU A N   1 
ATOM   2271 C  CA  . LEU A 1 299 ? 149.092 114.575 141.974 1.00 29.66  ? 299 LEU A CA  1 
ATOM   2272 C  C   . LEU A 1 299 ? 147.718 114.150 142.462 1.00 30.81  ? 299 LEU A C   1 
ATOM   2273 O  O   . LEU A 1 299 ? 147.402 114.293 143.646 1.00 40.95  ? 299 LEU A O   1 
ATOM   2274 C  CB  . LEU A 1 299 ? 149.046 115.996 141.422 1.00 29.31  ? 299 LEU A CB  1 
ATOM   2275 C  CG  . LEU A 1 299 ? 148.735 117.116 142.408 1.00 31.99  ? 299 LEU A CG  1 
ATOM   2276 C  CD1 . LEU A 1 299 ? 149.916 117.361 143.319 1.00 37.54  ? 299 LEU A CD1 1 
ATOM   2277 C  CD2 . LEU A 1 299 ? 148.369 118.377 141.654 1.00 33.18  ? 299 LEU A CD2 1 
ATOM   2278 N  N   . THR A 1 300 ? 146.881 113.632 141.563 1.00 28.96  ? 300 THR A N   1 
ATOM   2279 C  CA  . THR A 1 300 ? 145.555 113.180 141.970 1.00 31.31  ? 300 THR A CA  1 
ATOM   2280 C  C   . THR A 1 300 ? 145.590 111.943 142.859 1.00 34.41  ? 300 THR A C   1 
ATOM   2281 O  O   . THR A 1 300 ? 144.572 111.626 143.480 1.00 36.69  ? 300 THR A O   1 
ATOM   2282 C  CB  . THR A 1 300 ? 144.686 112.902 140.749 1.00 31.87  ? 300 THR A CB  1 
ATOM   2283 O  OG1 . THR A 1 300 ? 145.332 111.942 139.910 1.00 39.15  ? 300 THR A OG1 1 
ATOM   2284 C  CG2 . THR A 1 300 ? 144.453 114.177 139.974 1.00 27.54  ? 300 THR A CG2 1 
ATOM   2285 N  N   . GLU A 1 301 ? 146.717 111.238 142.932 1.00 43.43  ? 301 GLU A N   1 
ATOM   2286 C  CA  . GLU A 1 301 ? 146.875 110.132 143.868 1.00 46.17  ? 301 GLU A CA  1 
ATOM   2287 C  C   . GLU A 1 301 ? 147.488 110.592 145.182 1.00 43.98  ? 301 GLU A C   1 
ATOM   2288 O  O   . GLU A 1 301 ? 147.113 110.098 146.257 1.00 49.51  ? 301 GLU A O   1 
ATOM   2289 C  CB  . GLU A 1 301 ? 147.741 109.038 143.246 1.00 45.14  ? 301 GLU A CB  1 
ATOM   2290 C  CG  . GLU A 1 301 ? 147.087 108.307 142.097 1.00 46.11  ? 301 GLU A CG  1 
ATOM   2291 C  CD  . GLU A 1 301 ? 146.413 107.027 142.539 1.00 55.25  ? 301 GLU A CD  1 
ATOM   2292 O  OE1 . GLU A 1 301 ? 145.961 106.967 143.700 1.00 53.51  ? 301 GLU A OE1 1 
ATOM   2293 O  OE2 . GLU A 1 301 ? 146.338 106.081 141.727 1.00 55.46  ? 301 GLU A OE2 1 
ATOM   2294 N  N   . LEU A 1 302 ? 148.429 111.535 145.112 1.00 39.62  ? 302 LEU A N   1 
ATOM   2295 C  CA  . LEU A 1 302 ? 148.902 112.175 146.336 1.00 42.84  ? 302 LEU A CA  1 
ATOM   2296 C  C   . LEU A 1 302 ? 147.750 112.836 147.084 1.00 43.22  ? 302 LEU A C   1 
ATOM   2297 O  O   . LEU A 1 302 ? 147.700 112.802 148.319 1.00 45.31  ? 302 LEU A O   1 
ATOM   2298 C  CB  . LEU A 1 302 ? 149.984 113.202 146.019 1.00 37.20  ? 302 LEU A CB  1 
ATOM   2299 C  CG  . LEU A 1 302 ? 151.335 112.643 145.602 1.00 38.95  ? 302 LEU A CG  1 
ATOM   2300 C  CD1 . LEU A 1 302 ? 152.128 113.697 144.867 1.00 48.31  ? 302 LEU A CD1 1 
ATOM   2301 C  CD2 . LEU A 1 302 ? 152.081 112.163 146.821 1.00 43.28  ? 302 LEU A CD2 1 
ATOM   2302 N  N   . ASN A 1 303 ? 146.815 113.442 146.349 1.00 41.17  ? 303 ASN A N   1 
ATOM   2303 C  CA  . ASN A 1 303 ? 145.649 114.054 146.973 1.00 31.13  ? 303 ASN A CA  1 
ATOM   2304 C  C   . ASN A 1 303 ? 144.845 113.030 147.758 1.00 43.22  ? 303 ASN A C   1 
ATOM   2305 O  O   . ASN A 1 303 ? 144.490 113.264 148.915 1.00 56.10  ? 303 ASN A O   1 
ATOM   2306 C  CB  . ASN A 1 303 ? 144.770 114.715 145.913 1.00 30.17  ? 303 ASN A CB  1 
ATOM   2307 C  CG  . ASN A 1 303 ? 145.426 115.911 145.283 1.00 40.51  ? 303 ASN A CG  1 
ATOM   2308 O  OD1 . ASN A 1 303 ? 146.497 116.337 145.704 1.00 45.51  ? 303 ASN A OD1 1 
ATOM   2309 N  ND2 . ASN A 1 303 ? 144.788 116.465 144.263 1.00 41.82  ? 303 ASN A ND2 1 
ATOM   2310 N  N   . THR A 1 304 ? 144.546 111.884 147.145 1.00 40.63  ? 304 THR A N   1 
ATOM   2311 C  CA  . THR A 1 304 ? 143.768 110.863 147.837 1.00 39.16  ? 304 THR A CA  1 
ATOM   2312 C  C   . THR A 1 304 ? 144.492 110.381 149.086 1.00 38.75  ? 304 THR A C   1 
ATOM   2313 O  O   . THR A 1 304 ? 143.909 110.334 150.179 1.00 43.30  ? 304 THR A O   1 
ATOM   2314 C  CB  . THR A 1 304 ? 143.480 109.691 146.899 1.00 40.53  ? 304 THR A CB  1 
ATOM   2315 O  OG1 . THR A 1 304 ? 142.484 110.070 145.943 1.00 43.77  ? 304 THR A OG1 1 
ATOM   2316 C  CG2 . THR A 1 304 ? 142.980 108.500 147.682 1.00 41.95  ? 304 THR A CG2 1 
ATOM   2317 N  N   . PHE A 1 305 ? 145.777 110.041 148.946 1.00 41.23  ? 305 PHE A N   1 
ATOM   2318 C  CA  . PHE A 1 305 ? 146.535 109.533 150.086 1.00 36.39  ? 305 PHE A CA  1 
ATOM   2319 C  C   . PHE A 1 305 ? 146.537 110.532 151.233 1.00 43.74  ? 305 PHE A C   1 
ATOM   2320 O  O   . PHE A 1 305 ? 146.207 110.189 152.376 1.00 49.79  ? 305 PHE A O   1 
ATOM   2321 C  CB  . PHE A 1 305 ? 147.966 109.213 149.662 1.00 39.01  ? 305 PHE A CB  1 
ATOM   2322 C  CG  . PHE A 1 305 ? 148.790 108.572 150.740 1.00 44.02  ? 305 PHE A CG  1 
ATOM   2323 C  CD1 . PHE A 1 305 ? 148.731 107.208 150.956 1.00 50.71  ? 305 PHE A CD1 1 
ATOM   2324 C  CD2 . PHE A 1 305 ? 149.628 109.331 151.534 1.00 43.72  ? 305 PHE A CD2 1 
ATOM   2325 C  CE1 . PHE A 1 305 ? 149.490 106.616 151.943 1.00 46.87  ? 305 PHE A CE1 1 
ATOM   2326 C  CE2 . PHE A 1 305 ? 150.386 108.743 152.524 1.00 42.37  ? 305 PHE A CE2 1 
ATOM   2327 C  CZ  . PHE A 1 305 ? 150.316 107.385 152.727 1.00 45.16  ? 305 PHE A CZ  1 
ATOM   2328 N  N   . PHE A 1 306 ? 146.884 111.784 150.945 1.00 50.62  ? 306 PHE A N   1 
ATOM   2329 C  CA  . PHE A 1 306 ? 147.053 112.744 152.023 1.00 46.38  ? 306 PHE A CA  1 
ATOM   2330 C  C   . PHE A 1 306 ? 145.727 113.211 152.595 1.00 45.31  ? 306 PHE A C   1 
ATOM   2331 O  O   . PHE A 1 306 ? 145.660 113.510 153.785 1.00 55.08  ? 306 PHE A O   1 
ATOM   2332 C  CB  . PHE A 1 306 ? 147.890 113.925 151.548 1.00 44.06  ? 306 PHE A CB  1 
ATOM   2333 C  CG  . PHE A 1 306 ? 149.346 113.620 151.490 1.00 42.41  ? 306 PHE A CG  1 
ATOM   2334 C  CD1 . PHE A 1 306 ? 150.010 113.184 152.617 1.00 44.65  ? 306 PHE A CD1 1 
ATOM   2335 C  CD2 . PHE A 1 306 ? 150.046 113.738 150.310 1.00 46.46  ? 306 PHE A CD2 1 
ATOM   2336 C  CE1 . PHE A 1 306 ? 151.347 112.885 152.572 1.00 49.42  ? 306 PHE A CE1 1 
ATOM   2337 C  CE2 . PHE A 1 306 ? 151.386 113.440 150.260 1.00 51.82  ? 306 PHE A CE2 1 
ATOM   2338 C  CZ  . PHE A 1 306 ? 152.038 113.014 151.393 1.00 50.13  ? 306 PHE A CZ  1 
ATOM   2339 N  N   . LEU A 1 307 ? 144.662 113.267 151.795 1.00 41.04  ? 307 LEU A N   1 
ATOM   2340 C  CA  . LEU A 1 307 ? 143.352 113.564 152.357 1.00 40.72  ? 307 LEU A CA  1 
ATOM   2341 C  C   . LEU A 1 307 ? 142.928 112.476 153.330 1.00 47.26  ? 307 LEU A C   1 
ATOM   2342 O  O   . LEU A 1 307 ? 142.522 112.762 154.464 1.00 50.44  ? 307 LEU A O   1 
ATOM   2343 C  CB  . LEU A 1 307 ? 142.324 113.712 151.238 1.00 38.36  ? 307 LEU A CB  1 
ATOM   2344 C  CG  . LEU A 1 307 ? 142.312 115.031 150.475 1.00 44.07  ? 307 LEU A CG  1 
ATOM   2345 C  CD1 . LEU A 1 307 ? 141.229 114.995 149.427 1.00 44.47  ? 307 LEU A CD1 1 
ATOM   2346 C  CD2 . LEU A 1 307 ? 142.099 116.193 151.418 1.00 45.23  ? 307 LEU A CD2 1 
ATOM   2347 N  N   . LYS A 1 308 ? 143.043 111.212 152.911 1.00 54.64  ? 308 LYS A N   1 
ATOM   2348 C  CA  . LYS A 1 308 ? 142.646 110.113 153.783 1.00 50.82  ? 308 LYS A CA  1 
ATOM   2349 C  C   . LYS A 1 308 ? 143.497 110.058 155.044 1.00 51.48  ? 308 LYS A C   1 
ATOM   2350 O  O   . LYS A 1 308 ? 143.010 109.644 156.100 1.00 53.66  ? 308 LYS A O   1 
ATOM   2351 C  CB  . LYS A 1 308 ? 142.729 108.788 153.024 1.00 52.26  ? 308 LYS A CB  1 
ATOM   2352 C  CG  . LYS A 1 308 ? 142.425 107.564 153.866 1.00 54.82  ? 308 LYS A CG  1 
ATOM   2353 C  CD  . LYS A 1 308 ? 143.056 106.316 153.277 1.00 54.90  ? 308 LYS A CD  1 
ATOM   2354 C  CE  . LYS A 1 308 ? 142.530 105.064 153.960 1.00 59.19  ? 308 LYS A CE  1 
ATOM   2355 N  NZ  . LYS A 1 308 ? 143.560 103.991 154.045 1.00 55.01  ? 308 LYS A NZ  1 
ATOM   2356 N  N   . HIS A 1 309 ? 144.764 110.472 154.965 1.00 53.61  ? 309 HIS A N   1 
ATOM   2357 C  CA  . HIS A 1 309 ? 145.606 110.380 156.154 1.00 54.94  ? 309 HIS A CA  1 
ATOM   2358 C  C   . HIS A 1 309 ? 145.453 111.592 157.069 1.00 54.60  ? 309 HIS A C   1 
ATOM   2359 O  O   . HIS A 1 309 ? 145.496 111.449 158.295 1.00 59.96  ? 309 HIS A O   1 
ATOM   2360 C  CB  . HIS A 1 309 ? 147.064 110.187 155.751 1.00 54.69  ? 309 HIS A CB  1 
ATOM   2361 C  CG  . HIS A 1 309 ? 147.565 108.798 155.988 1.00 62.59  ? 309 HIS A CG  1 
ATOM   2362 N  ND1 . HIS A 1 309 ? 147.968 108.354 157.229 1.00 61.70  ? 309 HIS A ND1 1 
ATOM   2363 C  CD2 . HIS A 1 309 ? 147.700 107.743 155.150 1.00 62.28  ? 309 HIS A CD2 1 
ATOM   2364 C  CE1 . HIS A 1 309 ? 148.343 107.091 157.142 1.00 60.69  ? 309 HIS A CE1 1 
ATOM   2365 N  NE2 . HIS A 1 309 ? 148.190 106.696 155.891 1.00 60.78  ? 309 HIS A NE2 1 
ATOM   2366 N  N   . ILE A 1 310 ? 145.284 112.788 156.502 1.00 46.25  ? 310 ILE A N   1 
ATOM   2367 C  CA  . ILE A 1 310 ? 145.108 113.989 157.312 1.00 47.73  ? 310 ILE A CA  1 
ATOM   2368 C  C   . ILE A 1 310 ? 143.761 113.963 158.018 1.00 51.74  ? 310 ILE A C   1 
ATOM   2369 O  O   . ILE A 1 310 ? 143.670 114.211 159.226 1.00 50.65  ? 310 ILE A O   1 
ATOM   2370 C  CB  . ILE A 1 310 ? 145.258 115.244 156.435 1.00 47.13  ? 310 ILE A CB  1 
ATOM   2371 C  CG1 . ILE A 1 310 ? 146.726 115.499 156.114 1.00 51.64  ? 310 ILE A CG1 1 
ATOM   2372 C  CG2 . ILE A 1 310 ? 144.648 116.448 157.114 1.00 47.92  ? 310 ILE A CG2 1 
ATOM   2373 C  CD1 . ILE A 1 310 ? 146.929 116.385 154.926 1.00 50.98  ? 310 ILE A CD1 1 
ATOM   2374 N  N   . PHE A 1 311 ? 142.695 113.672 157.279 1.00 58.33  ? 311 PHE A N   1 
ATOM   2375 C  CA  . PHE A 1 311 ? 141.357 113.555 157.849 1.00 53.98  ? 311 PHE A CA  1 
ATOM   2376 C  C   . PHE A 1 311 ? 141.112 112.073 158.086 1.00 56.11  ? 311 PHE A C   1 
ATOM   2377 O  O   . PHE A 1 311 ? 140.736 111.342 157.169 1.00 60.82  ? 311 PHE A O   1 
ATOM   2378 C  CB  . PHE A 1 311 ? 140.315 114.165 156.921 1.00 48.87  ? 311 PHE A CB  1 
ATOM   2379 C  CG  . PHE A 1 311 ? 140.639 115.562 156.495 1.00 51.69  ? 311 PHE A CG  1 
ATOM   2380 C  CD1 . PHE A 1 311 ? 140.532 116.610 157.387 1.00 54.23  ? 311 PHE A CD1 1 
ATOM   2381 C  CD2 . PHE A 1 311 ? 141.064 115.825 155.208 1.00 55.83  ? 311 PHE A CD2 1 
ATOM   2382 C  CE1 . PHE A 1 311 ? 140.836 117.892 157.000 1.00 56.62  ? 311 PHE A CE1 1 
ATOM   2383 C  CE2 . PHE A 1 311 ? 141.370 117.107 154.817 1.00 57.06  ? 311 PHE A CE2 1 
ATOM   2384 C  CZ  . PHE A 1 311 ? 141.255 118.141 155.713 1.00 57.26  ? 311 PHE A CZ  1 
ATOM   2385 N  N   . VAL A 1 312 ? 141.327 111.630 159.320 1.00 57.28  ? 312 VAL A N   1 
ATOM   2386 C  CA  . VAL A 1 312 ? 141.376 110.203 159.602 1.00 59.75  ? 312 VAL A CA  1 
ATOM   2387 C  C   . VAL A 1 312 ? 139.988 109.598 159.465 1.00 61.72  ? 312 VAL A C   1 
ATOM   2388 O  O   . VAL A 1 312 ? 139.140 109.750 160.350 1.00 62.72  ? 312 VAL A O   1 
ATOM   2389 C  CB  . VAL A 1 312 ? 141.954 109.938 161.003 1.00 58.13  ? 312 VAL A CB  1 
ATOM   2390 C  CG1 . VAL A 1 312 ? 142.257 108.460 161.182 1.00 56.88  ? 312 VAL A CG1 1 
ATOM   2391 C  CG2 . VAL A 1 312 ? 143.202 110.775 161.227 1.00 57.15  ? 312 VAL A CG2 1 
ATOM   2392 N  N   . PHE A 1 313 ? 139.751 108.909 158.352 1.00 57.78  ? 313 PHE A N   1 
ATOM   2393 C  CA  . PHE A 1 313 ? 138.580 108.060 158.202 1.00 58.41  ? 313 PHE A CA  1 
ATOM   2394 C  C   . PHE A 1 313 ? 138.998 106.780 157.497 1.00 62.08  ? 313 PHE A C   1 
ATOM   2395 O  O   . PHE A 1 313 ? 139.947 106.767 156.710 1.00 58.13  ? 313 PHE A O   1 
ATOM   2396 C  CB  . PHE A 1 313 ? 137.435 108.750 157.436 1.00 58.45  ? 313 PHE A CB  1 
ATOM   2397 C  CG  . PHE A 1 313 ? 137.870 109.504 156.213 1.00 57.90  ? 313 PHE A CG  1 
ATOM   2398 C  CD1 . PHE A 1 313 ? 138.240 108.837 155.064 1.00 62.85  ? 313 PHE A CD1 1 
ATOM   2399 C  CD2 . PHE A 1 313 ? 137.872 110.885 156.206 1.00 57.70  ? 313 PHE A CD2 1 
ATOM   2400 C  CE1 . PHE A 1 313 ? 138.627 109.531 153.940 1.00 61.97  ? 313 PHE A CE1 1 
ATOM   2401 C  CE2 . PHE A 1 313 ? 138.259 111.584 155.085 1.00 57.37  ? 313 PHE A CE2 1 
ATOM   2402 C  CZ  . PHE A 1 313 ? 138.636 110.908 153.951 1.00 58.35  ? 313 PHE A CZ  1 
ATOM   2403 N  N   . GLN A 1 314 ? 138.285 105.700 157.796 1.00 74.33  ? 314 GLN A N   1 
ATOM   2404 C  CA  . GLN A 1 314 ? 138.610 104.411 157.213 1.00 71.70  ? 314 GLN A CA  1 
ATOM   2405 C  C   . GLN A 1 314 ? 138.305 104.409 155.720 1.00 72.62  ? 314 GLN A C   1 
ATOM   2406 O  O   . GLN A 1 314 ? 137.553 105.243 155.209 1.00 73.15  ? 314 GLN A O   1 
ATOM   2407 C  CB  . GLN A 1 314 ? 137.833 103.296 157.911 1.00 70.76  ? 314 GLN A CB  1 
ATOM   2408 C  CG  . GLN A 1 314 ? 138.153 103.151 159.387 1.00 74.56  ? 314 GLN A CG  1 
ATOM   2409 C  CD  . GLN A 1 314 ? 137.115 102.335 160.128 1.00 77.14  ? 314 GLN A CD  1 
ATOM   2410 O  OE1 . GLN A 1 314 ? 136.159 101.840 159.533 1.00 78.15  ? 314 GLN A OE1 1 
ATOM   2411 N  NE2 . GLN A 1 314 ? 137.294 102.195 161.436 1.00 74.01  ? 314 GLN A NE2 1 
ATOM   2412 N  N   . ALA A 1 315 ? 138.910 103.454 155.014 1.00 70.97  ? 315 ALA A N   1 
ATOM   2413 C  CA  . ALA A 1 315 ? 138.677 103.333 153.582 1.00 71.96  ? 315 ALA A CA  1 
ATOM   2414 C  C   . ALA A 1 315 ? 137.245 102.935 153.262 1.00 73.15  ? 315 ALA A C   1 
ATOM   2415 O  O   . ALA A 1 315 ? 136.801 103.129 152.127 1.00 71.73  ? 315 ALA A O   1 
ATOM   2416 C  CB  . ALA A 1 315 ? 139.648 102.323 152.975 1.00 71.67  ? 315 ALA A CB  1 
ATOM   2417 N  N   . SER A 1 316 ? 136.515 102.386 154.232 1.00 71.09  ? 316 SER A N   1 
ATOM   2418 C  CA  . SER A 1 316 ? 135.127 101.998 154.030 1.00 68.31  ? 316 SER A CA  1 
ATOM   2419 C  C   . SER A 1 316 ? 134.152 103.158 154.175 1.00 68.15  ? 316 SER A C   1 
ATOM   2420 O  O   . SER A 1 316 ? 132.983 103.009 153.806 1.00 66.73  ? 316 SER A O   1 
ATOM   2421 C  CB  . SER A 1 316 ? 134.749 100.891 155.015 1.00 71.09  ? 316 SER A CB  1 
ATOM   2422 O  OG  . SER A 1 316 ? 135.034 101.280 156.346 1.00 69.96  ? 316 SER A OG  1 
ATOM   2423 N  N   . HIS A 1 317 ? 134.594 104.293 154.706 1.00 65.75  ? 317 HIS A N   1 
ATOM   2424 C  CA  . HIS A 1 317 ? 133.700 105.426 154.879 1.00 62.90  ? 317 HIS A CA  1 
ATOM   2425 C  C   . HIS A 1 317 ? 133.322 106.008 153.520 1.00 63.71  ? 317 HIS A C   1 
ATOM   2426 O  O   . HIS A 1 317 ? 134.149 106.030 152.605 1.00 68.14  ? 317 HIS A O   1 
ATOM   2427 C  CB  . HIS A 1 317 ? 134.354 106.503 155.738 1.00 60.76  ? 317 HIS A CB  1 
ATOM   2428 C  CG  . HIS A 1 317 ? 133.385 107.493 156.300 1.00 64.23  ? 317 HIS A CG  1 
ATOM   2429 N  ND1 . HIS A 1 317 ? 133.192 108.740 155.748 1.00 65.23  ? 317 HIS A ND1 1 
ATOM   2430 C  CD2 . HIS A 1 317 ? 132.550 107.419 157.362 1.00 66.65  ? 317 HIS A CD2 1 
ATOM   2431 C  CE1 . HIS A 1 317 ? 132.280 109.392 156.445 1.00 63.57  ? 317 HIS A CE1 1 
ATOM   2432 N  NE2 . HIS A 1 317 ? 131.875 108.613 157.431 1.00 68.80  ? 317 HIS A NE2 1 
ATOM   2433 N  N   . PRO A 1 318 ? 132.086 106.486 153.356 1.00 54.73  ? 318 PRO A N   1 
ATOM   2434 C  CA  . PRO A 1 318 ? 131.699 107.075 152.067 1.00 51.89  ? 318 PRO A CA  1 
ATOM   2435 C  C   . PRO A 1 318 ? 132.548 108.261 151.661 1.00 53.96  ? 318 PRO A C   1 
ATOM   2436 O  O   . PRO A 1 318 ? 132.700 108.509 150.462 1.00 59.49  ? 318 PRO A O   1 
ATOM   2437 C  CB  . PRO A 1 318 ? 130.238 107.476 152.296 1.00 52.82  ? 318 PRO A CB  1 
ATOM   2438 C  CG  . PRO A 1 318 ? 129.765 106.551 153.342 1.00 57.97  ? 318 PRO A CG  1 
ATOM   2439 C  CD  . PRO A 1 318 ? 130.933 106.347 154.258 1.00 57.08  ? 318 PRO A CD  1 
ATOM   2440 N  N   . LEU A 1 319 ? 133.124 108.993 152.613 1.00 52.12  ? 319 LEU A N   1 
ATOM   2441 C  CA  . LEU A 1 319 ? 133.989 110.109 152.252 1.00 48.19  ? 319 LEU A CA  1 
ATOM   2442 C  C   . LEU A 1 319 ? 135.198 109.657 151.449 1.00 47.19  ? 319 LEU A C   1 
ATOM   2443 O  O   . LEU A 1 319 ? 135.826 110.483 150.781 1.00 52.84  ? 319 LEU A O   1 
ATOM   2444 C  CB  . LEU A 1 319 ? 134.455 110.850 153.505 1.00 51.56  ? 319 LEU A CB  1 
ATOM   2445 C  CG  . LEU A 1 319 ? 133.481 111.827 154.160 1.00 54.77  ? 319 LEU A CG  1 
ATOM   2446 C  CD1 . LEU A 1 319 ? 134.155 112.538 155.316 1.00 51.75  ? 319 LEU A CD1 1 
ATOM   2447 C  CD2 . LEU A 1 319 ? 132.965 112.825 153.148 1.00 55.08  ? 319 LEU A CD2 1 
ATOM   2448 N  N   . SER A 1 320 ? 135.543 108.372 151.504 1.00 53.38  ? 320 SER A N   1 
ATOM   2449 C  CA  . SER A 1 320 ? 136.689 107.850 150.769 1.00 54.85  ? 320 SER A CA  1 
ATOM   2450 C  C   . SER A 1 320 ? 136.284 107.268 149.418 1.00 56.14  ? 320 SER A C   1 
ATOM   2451 O  O   . SER A 1 320 ? 136.697 107.768 148.366 1.00 58.64  ? 320 SER A O   1 
ATOM   2452 C  CB  . SER A 1 320 ? 137.404 106.792 151.616 1.00 56.04  ? 320 SER A CB  1 
ATOM   2453 O  OG  . SER A 1 320 ? 138.284 106.016 150.827 1.00 62.78  ? 320 SER A OG  1 
ATOM   2454 N  N   . TRP A 1 321 ? 135.453 106.225 149.427 1.00 52.57  ? 321 TRP A N   1 
ATOM   2455 C  CA  . TRP A 1 321 ? 135.122 105.574 148.168 1.00 51.96  ? 321 TRP A CA  1 
ATOM   2456 C  C   . TRP A 1 321 ? 134.118 106.373 147.352 1.00 51.67  ? 321 TRP A C   1 
ATOM   2457 O  O   . TRP A 1 321 ? 134.142 106.295 146.123 1.00 59.68  ? 321 TRP A O   1 
ATOM   2458 C  CB  . TRP A 1 321 ? 134.620 104.149 148.405 1.00 50.18  ? 321 TRP A CB  1 
ATOM   2459 C  CG  . TRP A 1 321 ? 133.456 104.008 149.315 1.00 51.12  ? 321 TRP A CG  1 
ATOM   2460 C  CD1 . TRP A 1 321 ? 133.489 103.688 150.636 1.00 54.94  ? 321 TRP A CD1 1 
ATOM   2461 C  CD2 . TRP A 1 321 ? 132.074 104.137 148.967 1.00 54.31  ? 321 TRP A CD2 1 
ATOM   2462 N  NE1 . TRP A 1 321 ? 132.214 103.626 151.139 1.00 56.83  ? 321 TRP A NE1 1 
ATOM   2463 C  CE2 . TRP A 1 321 ? 131.327 103.899 150.133 1.00 53.07  ? 321 TRP A CE2 1 
ATOM   2464 C  CE3 . TRP A 1 321 ? 131.396 104.440 147.785 1.00 55.58  ? 321 TRP A CE3 1 
ATOM   2465 C  CZ2 . TRP A 1 321 ? 129.940 103.955 150.152 1.00 53.63  ? 321 TRP A CZ2 1 
ATOM   2466 C  CZ3 . TRP A 1 321 ? 130.019 104.495 147.806 1.00 54.44  ? 321 TRP A CZ3 1 
ATOM   2467 C  CH2 . TRP A 1 321 ? 129.306 104.255 148.980 1.00 55.64  ? 321 TRP A CH2 1 
ATOM   2468 N  N   . GLY A 1 322 ? 133.244 107.150 147.989 1.00 43.58  ? 322 GLY A N   1 
ATOM   2469 C  CA  . GLY A 1 322 ? 132.403 108.057 147.229 1.00 42.60  ? 322 GLY A CA  1 
ATOM   2470 C  C   . GLY A 1 322 ? 133.210 109.108 146.494 1.00 44.64  ? 322 GLY A C   1 
ATOM   2471 O  O   . GLY A 1 322 ? 132.948 109.402 145.326 1.00 54.57  ? 322 GLY A O   1 
ATOM   2472 N  N   . ARG A 1 323 ? 134.214 109.678 147.163 1.00 39.77  ? 323 ARG A N   1 
ATOM   2473 C  CA  . ARG A 1 323 ? 135.091 110.637 146.501 1.00 39.97  ? 323 ARG A CA  1 
ATOM   2474 C  C   . ARG A 1 323 ? 135.871 109.980 145.373 1.00 42.00  ? 323 ARG A C   1 
ATOM   2475 O  O   . ARG A 1 323 ? 136.056 110.577 144.306 1.00 42.12  ? 323 ARG A O   1 
ATOM   2476 C  CB  . ARG A 1 323 ? 136.050 111.263 147.509 1.00 37.42  ? 323 ARG A CB  1 
ATOM   2477 C  CG  . ARG A 1 323 ? 137.057 112.194 146.872 1.00 38.75  ? 323 ARG A CG  1 
ATOM   2478 C  CD  . ARG A 1 323 ? 138.166 112.570 147.828 1.00 38.15  ? 323 ARG A CD  1 
ATOM   2479 N  NE  . ARG A 1 323 ? 139.265 113.223 147.130 1.00 38.81  ? 323 ARG A NE  1 
ATOM   2480 C  CZ  . ARG A 1 323 ? 140.187 112.587 146.424 1.00 42.26  ? 323 ARG A CZ  1 
ATOM   2481 N  NH1 . ARG A 1 323 ? 140.197 111.270 146.328 1.00 46.29  ? 323 ARG A NH1 1 
ATOM   2482 N  NH2 . ARG A 1 323 ? 141.124 113.290 145.798 1.00 44.74  ? 323 ARG A NH2 1 
ATOM   2483 N  N   . ILE A 1 324 ? 136.349 108.755 145.593 1.00 48.29  ? 324 ILE A N   1 
ATOM   2484 C  CA  . ILE A 1 324 ? 137.094 108.057 144.549 1.00 42.03  ? 324 ILE A CA  1 
ATOM   2485 C  C   . ILE A 1 324 ? 136.202 107.781 143.343 1.00 43.72  ? 324 ILE A C   1 
ATOM   2486 O  O   . ILE A 1 324 ? 136.614 107.974 142.194 1.00 51.51  ? 324 ILE A O   1 
ATOM   2487 C  CB  . ILE A 1 324 ? 137.714 106.767 145.112 1.00 43.79  ? 324 ILE A CB  1 
ATOM   2488 C  CG1 . ILE A 1 324 ? 138.954 107.105 145.935 1.00 47.26  ? 324 ILE A CG1 1 
ATOM   2489 C  CG2 . ILE A 1 324 ? 138.080 105.826 143.998 1.00 47.55  ? 324 ILE A CG2 1 
ATOM   2490 C  CD1 . ILE A 1 324 ? 139.260 106.104 147.006 1.00 46.18  ? 324 ILE A CD1 1 
ATOM   2491 N  N   . LEU A 1 325 ? 134.966 107.339 143.583 1.00 42.41  ? 325 LEU A N   1 
ATOM   2492 C  CA  . LEU A 1 325 ? 134.027 107.112 142.489 1.00 41.36  ? 325 LEU A CA  1 
ATOM   2493 C  C   . LEU A 1 325 ? 133.732 108.402 141.739 1.00 45.55  ? 325 LEU A C   1 
ATOM   2494 O  O   . LEU A 1 325 ? 133.651 108.407 140.507 1.00 48.28  ? 325 LEU A O   1 
ATOM   2495 C  CB  . LEU A 1 325 ? 132.729 106.513 143.027 1.00 43.86  ? 325 LEU A CB  1 
ATOM   2496 C  CG  . LEU A 1 325 ? 132.725 105.056 143.480 1.00 46.49  ? 325 LEU A CG  1 
ATOM   2497 C  CD1 . LEU A 1 325 ? 131.407 104.731 144.145 1.00 47.72  ? 325 LEU A CD1 1 
ATOM   2498 C  CD2 . LEU A 1 325 ? 132.956 104.137 142.307 1.00 49.67  ? 325 LEU A CD2 1 
ATOM   2499 N  N   . PHE A 1 326 ? 133.551 109.504 142.465 1.00 40.93  ? 326 PHE A N   1 
ATOM   2500 C  CA  . PHE A 1 326 ? 133.250 110.772 141.813 1.00 38.15  ? 326 PHE A CA  1 
ATOM   2501 C  C   . PHE A 1 326 ? 134.420 111.257 140.961 1.00 42.82  ? 326 PHE A C   1 
ATOM   2502 O  O   . PHE A 1 326 ? 134.221 111.726 139.834 1.00 46.51  ? 326 PHE A O   1 
ATOM   2503 C  CB  . PHE A 1 326 ? 132.875 111.811 142.862 1.00 37.15  ? 326 PHE A CB  1 
ATOM   2504 C  CG  . PHE A 1 326 ? 132.847 113.206 142.341 1.00 41.19  ? 326 PHE A CG  1 
ATOM   2505 C  CD1 . PHE A 1 326 ? 131.957 113.566 141.349 1.00 38.69  ? 326 PHE A CD1 1 
ATOM   2506 C  CD2 . PHE A 1 326 ? 133.713 114.159 142.841 1.00 41.09  ? 326 PHE A CD2 1 
ATOM   2507 C  CE1 . PHE A 1 326 ? 131.934 114.843 140.867 1.00 35.19  ? 326 PHE A CE1 1 
ATOM   2508 C  CE2 . PHE A 1 326 ? 133.692 115.439 142.362 1.00 40.84  ? 326 PHE A CE2 1 
ATOM   2509 C  CZ  . PHE A 1 326 ? 132.799 115.782 141.378 1.00 44.07  ? 326 PHE A CZ  1 
ATOM   2510 N  N   . ILE A 1 327 ? 135.646 111.150 141.475 1.00 39.89  ? 327 ILE A N   1 
ATOM   2511 C  CA  . ILE A 1 327 ? 136.810 111.547 140.689 1.00 33.41  ? 327 ILE A CA  1 
ATOM   2512 C  C   . ILE A 1 327 ? 136.975 110.633 139.480 1.00 37.91  ? 327 ILE A C   1 
ATOM   2513 O  O   . ILE A 1 327 ? 137.348 111.084 138.392 1.00 48.42  ? 327 ILE A O   1 
ATOM   2514 C  CB  . ILE A 1 327 ? 138.071 111.566 141.572 1.00 35.78  ? 327 ILE A CB  1 
ATOM   2515 C  CG1 . ILE A 1 327 ? 137.946 112.633 142.656 1.00 33.90  ? 327 ILE A CG1 1 
ATOM   2516 C  CG2 . ILE A 1 327 ? 139.307 111.830 140.744 1.00 34.37  ? 327 ILE A CG2 1 
ATOM   2517 C  CD1 . ILE A 1 327 ? 138.088 114.038 142.147 1.00 41.75  ? 327 ILE A CD1 1 
ATOM   2518 N  N   . GLY A 1 328 ? 136.689 109.341 139.640 1.00 33.92  ? 328 GLY A N   1 
ATOM   2519 C  CA  . GLY A 1 328 ? 136.756 108.437 138.504 1.00 35.58  ? 328 GLY A CA  1 
ATOM   2520 C  C   . GLY A 1 328 ? 135.723 108.754 137.441 1.00 41.25  ? 328 GLY A C   1 
ATOM   2521 O  O   . GLY A 1 328 ? 135.988 108.615 136.246 1.00 40.79  ? 328 GLY A O   1 
ATOM   2522 N  N   . GLY A 1 329 ? 134.527 109.164 137.860 1.00 40.69  ? 329 GLY A N   1 
ATOM   2523 C  CA  . GLY A 1 329 ? 133.526 109.595 136.898 1.00 35.12  ? 329 GLY A CA  1 
ATOM   2524 C  C   . GLY A 1 329 ? 133.918 110.877 136.191 1.00 34.52  ? 329 GLY A C   1 
ATOM   2525 O  O   . GLY A 1 329 ? 133.649 111.047 135.001 1.00 42.11  ? 329 GLY A O   1 
ATOM   2526 N  N   . ILE A 1 330 ? 134.549 111.800 136.919 1.00 34.92  ? 330 ILE A N   1 
ATOM   2527 C  CA  . ILE A 1 330 ? 135.053 113.030 136.312 1.00 28.70  ? 330 ILE A CA  1 
ATOM   2528 C  C   . ILE A 1 330 ? 136.131 112.717 135.282 1.00 31.19  ? 330 ILE A C   1 
ATOM   2529 O  O   . ILE A 1 330 ? 136.221 113.366 134.235 1.00 32.48  ? 330 ILE A O   1 
ATOM   2530 C  CB  . ILE A 1 330 ? 135.599 113.968 137.402 1.00 33.84  ? 330 ILE A CB  1 
ATOM   2531 C  CG1 . ILE A 1 330 ? 134.507 114.821 138.020 1.00 41.12  ? 330 ILE A CG1 1 
ATOM   2532 C  CG2 . ILE A 1 330 ? 136.610 114.906 136.824 1.00 34.98  ? 330 ILE A CG2 1 
ATOM   2533 C  CD1 . ILE A 1 330 ? 135.089 115.913 138.888 1.00 43.01  ? 330 ILE A CD1 1 
ATOM   2534 N  N   . THR A 1 331 ? 136.977 111.728 135.577 1.00 32.91  ? 331 THR A N   1 
ATOM   2535 C  CA  . THR A 1 331 ? 138.170 111.477 134.775 1.00 24.42  ? 331 THR A CA  1 
ATOM   2536 C  C   . THR A 1 331 ? 137.838 111.084 133.340 1.00 30.57  ? 331 THR A C   1 
ATOM   2537 O  O   . THR A 1 331 ? 138.600 111.403 132.422 1.00 36.44  ? 331 THR A O   1 
ATOM   2538 C  CB  . THR A 1 331 ? 139.010 110.389 135.448 1.00 28.98  ? 331 THR A CB  1 
ATOM   2539 O  OG1 . THR A 1 331 ? 139.569 110.902 136.662 1.00 36.44  ? 331 THR A OG1 1 
ATOM   2540 C  CG2 . THR A 1 331 ? 140.129 109.920 134.549 1.00 34.59  ? 331 THR A CG2 1 
ATOM   2541 N  N   . ALA A 1 332 ? 136.708 110.414 133.120 1.00 27.08  ? 332 ALA A N   1 
ATOM   2542 C  CA  . ALA A 1 332 ? 136.410 109.891 131.788 1.00 22.40  ? 332 ALA A CA  1 
ATOM   2543 C  C   . ALA A 1 332 ? 136.313 110.976 130.720 1.00 25.88  ? 332 ALA A C   1 
ATOM   2544 O  O   . ALA A 1 332 ? 136.902 110.792 129.641 1.00 36.39  ? 332 ALA A O   1 
ATOM   2545 C  CB  . ALA A 1 332 ? 135.145 109.029 131.846 1.00 29.16  ? 332 ALA A CB  1 
ATOM   2546 N  N   . PRO A 1 333 ? 135.608 112.101 130.919 1.00 21.66  ? 333 PRO A N   1 
ATOM   2547 C  CA  . PRO A 1 333 ? 135.683 113.182 129.922 1.00 21.47  ? 333 PRO A CA  1 
ATOM   2548 C  C   . PRO A 1 333 ? 136.905 114.076 130.052 1.00 26.70  ? 333 PRO A C   1 
ATOM   2549 O  O   . PRO A 1 333 ? 137.294 114.701 129.058 1.00 38.20  ? 333 PRO A O   1 
ATOM   2550 C  CB  . PRO A 1 333 ? 134.399 113.979 130.172 1.00 19.97  ? 333 PRO A CB  1 
ATOM   2551 C  CG  . PRO A 1 333 ? 134.096 113.747 131.581 1.00 21.95  ? 333 PRO A CG  1 
ATOM   2552 C  CD  . PRO A 1 333 ? 134.513 112.341 131.875 1.00 21.14  ? 333 PRO A CD  1 
ATOM   2553 N  N   . THR A 1 334 ? 137.520 114.164 131.231 1.00 20.61  ? 334 THR A N   1 
ATOM   2554 C  CA  . THR A 1 334 ? 138.709 114.995 131.385 1.00 7.61   ? 334 THR A CA  1 
ATOM   2555 C  C   . THR A 1 334 ? 139.855 114.488 130.524 1.00 18.24  ? 334 THR A C   1 
ATOM   2556 O  O   . THR A 1 334 ? 140.570 115.280 129.904 1.00 37.66  ? 334 THR A O   1 
ATOM   2557 C  CB  . THR A 1 334 ? 139.133 115.037 132.847 1.00 21.04  ? 334 THR A CB  1 
ATOM   2558 O  OG1 . THR A 1 334 ? 138.137 115.719 133.612 1.00 28.91  ? 334 THR A OG1 1 
ATOM   2559 C  CG2 . THR A 1 334 ? 140.455 115.757 132.991 1.00 25.84  ? 334 THR A CG2 1 
ATOM   2560 N  N   . VAL A 1 335 ? 140.056 113.170 130.486 1.00 18.91  ? 335 VAL A N   1 
ATOM   2561 C  CA  . VAL A 1 335 ? 141.121 112.605 129.664 1.00 17.51  ? 335 VAL A CA  1 
ATOM   2562 C  C   . VAL A 1 335 ? 140.858 112.879 128.191 1.00 23.38  ? 335 VAL A C   1 
ATOM   2563 O  O   . VAL A 1 335 ? 141.764 113.266 127.442 1.00 39.04  ? 335 VAL A O   1 
ATOM   2564 C  CB  . VAL A 1 335 ? 141.263 111.098 129.942 1.00 17.38  ? 335 VAL A CB  1 
ATOM   2565 C  CG1 . VAL A 1 335 ? 142.234 110.471 128.973 1.00 30.72  ? 335 VAL A CG1 1 
ATOM   2566 C  CG2 . VAL A 1 335 ? 141.711 110.869 131.360 1.00 22.86  ? 335 VAL A CG2 1 
ATOM   2567 N  N   . ARG A 1 336 ? 139.613 112.697 127.755 1.00 22.91  ? 336 ARG A N   1 
ATOM   2568 C  CA  . ARG A 1 336 ? 139.270 112.873 126.352 1.00 24.13  ? 336 ARG A CA  1 
ATOM   2569 C  C   . ARG A 1 336 ? 139.244 114.335 125.934 1.00 21.48  ? 336 ARG A C   1 
ATOM   2570 O  O   . ARG A 1 336 ? 139.262 114.620 124.735 1.00 31.47  ? 336 ARG A O   1 
ATOM   2571 C  CB  . ARG A 1 336 ? 137.920 112.223 126.065 1.00 29.07  ? 336 ARG A CB  1 
ATOM   2572 C  CG  . ARG A 1 336 ? 137.968 110.711 126.015 1.00 23.26  ? 336 ARG A CG  1 
ATOM   2573 C  CD  . ARG A 1 336 ? 138.003 110.223 124.583 1.00 31.55  ? 336 ARG A CD  1 
ATOM   2574 N  NE  . ARG A 1 336 ? 138.111 108.774 124.492 1.00 29.59  ? 336 ARG A NE  1 
ATOM   2575 C  CZ  . ARG A 1 336 ? 139.260 108.118 124.446 1.00 36.29  ? 336 ARG A CZ  1 
ATOM   2576 N  NH1 . ARG A 1 336 ? 140.418 108.754 124.491 1.00 41.97  ? 336 ARG A NH1 1 
ATOM   2577 N  NH2 . ARG A 1 336 ? 139.248 106.793 124.351 1.00 37.12  ? 336 ARG A NH2 1 
ATOM   2578 N  N   . GLN A 1 337 ? 139.173 115.263 126.885 1.00 21.95  ? 337 GLN A N   1 
ATOM   2579 C  CA  . GLN A 1 337 ? 139.295 116.678 126.563 1.00 16.18  ? 337 GLN A CA  1 
ATOM   2580 C  C   . GLN A 1 337 ? 140.739 117.156 126.600 1.00 19.85  ? 337 GLN A C   1 
ATOM   2581 O  O   . GLN A 1 337 ? 141.142 117.970 125.764 1.00 30.59  ? 337 GLN A O   1 
ATOM   2582 C  CB  . GLN A 1 337 ? 138.454 117.510 127.525 1.00 15.20  ? 337 GLN A CB  1 
ATOM   2583 C  CG  . GLN A 1 337 ? 136.976 117.369 127.308 1.00 12.90  ? 337 GLN A CG  1 
ATOM   2584 C  CD  . GLN A 1 337 ? 136.198 118.351 128.121 1.00 18.90  ? 337 GLN A CD  1 
ATOM   2585 O  OE1 . GLN A 1 337 ? 136.758 119.052 128.949 1.00 36.09  ? 337 GLN A OE1 1 
ATOM   2586 N  NE2 . GLN A 1 337 ? 134.902 118.416 127.892 1.00 20.66  ? 337 GLN A NE2 1 
ATOM   2587 N  N   . TYR A 1 338 ? 141.530 116.672 127.559 1.00 28.11  ? 338 TYR A N   1 
ATOM   2588 C  CA  . TYR A 1 338 ? 142.948 117.005 127.583 1.00 22.53  ? 338 TYR A CA  1 
ATOM   2589 C  C   . TYR A 1 338 ? 143.655 116.464 126.352 1.00 29.89  ? 338 TYR A C   1 
ATOM   2590 O  O   . TYR A 1 338 ? 144.503 117.147 125.771 1.00 43.78  ? 338 TYR A O   1 
ATOM   2591 C  CB  . TYR A 1 338 ? 143.602 116.464 128.852 1.00 29.91  ? 338 TYR A CB  1 
ATOM   2592 C  CG  . TYR A 1 338 ? 145.031 116.922 129.052 1.00 33.71  ? 338 TYR A CG  1 
ATOM   2593 C  CD1 . TYR A 1 338 ? 146.081 116.293 128.406 1.00 31.41  ? 338 TYR A CD1 1 
ATOM   2594 C  CD2 . TYR A 1 338 ? 145.329 117.975 129.893 1.00 34.13  ? 338 TYR A CD2 1 
ATOM   2595 C  CE1 . TYR A 1 338 ? 147.375 116.705 128.586 1.00 30.64  ? 338 TYR A CE1 1 
ATOM   2596 C  CE2 . TYR A 1 338 ? 146.624 118.386 130.081 1.00 30.94  ? 338 TYR A CE2 1 
ATOM   2597 C  CZ  . TYR A 1 338 ? 147.641 117.750 129.423 1.00 32.23  ? 338 TYR A CZ  1 
ATOM   2598 O  OH  . TYR A 1 338 ? 148.937 118.160 129.602 1.00 42.71  ? 338 TYR A OH  1 
ATOM   2599 N  N   . TYR A 1 339 ? 143.332 115.237 125.941 1.00 28.44  ? 339 TYR A N   1 
ATOM   2600 C  CA  . TYR A 1 339 ? 143.927 114.698 124.724 1.00 24.98  ? 339 TYR A CA  1 
ATOM   2601 C  C   . TYR A 1 339 ? 143.560 115.545 123.516 1.00 31.78  ? 339 TYR A C   1 
ATOM   2602 O  O   . TYR A 1 339 ? 144.421 115.869 122.689 1.00 48.17  ? 339 TYR A O   1 
ATOM   2603 C  CB  . TYR A 1 339 ? 143.480 113.254 124.515 1.00 27.98  ? 339 TYR A CB  1 
ATOM   2604 C  CG  . TYR A 1 339 ? 143.853 112.701 123.164 1.00 36.74  ? 339 TYR A CG  1 
ATOM   2605 C  CD1 . TYR A 1 339 ? 145.158 112.330 122.883 1.00 39.34  ? 339 TYR A CD1 1 
ATOM   2606 C  CD2 . TYR A 1 339 ? 142.905 112.552 122.170 1.00 38.08  ? 339 TYR A CD2 1 
ATOM   2607 C  CE1 . TYR A 1 339 ? 145.503 111.826 121.654 1.00 32.34  ? 339 TYR A CE1 1 
ATOM   2608 C  CE2 . TYR A 1 339 ? 143.244 112.050 120.937 1.00 36.54  ? 339 TYR A CE2 1 
ATOM   2609 C  CZ  . TYR A 1 339 ? 144.545 111.692 120.685 1.00 36.41  ? 339 TYR A CZ  1 
ATOM   2610 O  OH  . TYR A 1 339 ? 144.888 111.189 119.454 1.00 43.32  ? 339 TYR A OH  1 
ATOM   2611 N  N   . ALA A 1 340 ? 142.288 115.926 123.406 1.00 21.87  ? 340 ALA A N   1 
ATOM   2612 C  CA  . ALA A 1 340 ? 141.848 116.713 122.263 1.00 16.05  ? 340 ALA A CA  1 
ATOM   2613 C  C   . ALA A 1 340 ? 142.537 118.068 122.222 1.00 21.34  ? 340 ALA A C   1 
ATOM   2614 O  O   . ALA A 1 340 ? 142.972 118.514 121.157 1.00 36.46  ? 340 ALA A O   1 
ATOM   2615 C  CB  . ALA A 1 340 ? 140.333 116.882 122.298 1.00 24.51  ? 340 ALA A CB  1 
ATOM   2616 N  N   . TYR A 1 341 ? 142.650 118.741 123.368 1.00 31.17  ? 341 TYR A N   1 
ATOM   2617 C  CA  . TYR A 1 341 ? 143.355 120.018 123.395 1.00 26.65  ? 341 TYR A CA  1 
ATOM   2618 C  C   . TYR A 1 341 ? 144.829 119.842 123.063 1.00 27.51  ? 341 TYR A C   1 
ATOM   2619 O  O   . TYR A 1 341 ? 145.398 120.631 122.305 1.00 34.52  ? 341 TYR A O   1 
ATOM   2620 C  CB  . TYR A 1 341 ? 143.203 120.686 124.758 1.00 27.05  ? 341 TYR A CB  1 
ATOM   2621 C  CG  . TYR A 1 341 ? 143.966 121.983 124.880 1.00 32.52  ? 341 TYR A CG  1 
ATOM   2622 C  CD1 . TYR A 1 341 ? 143.461 123.156 124.353 1.00 32.71  ? 341 TYR A CD1 1 
ATOM   2623 C  CD2 . TYR A 1 341 ? 145.191 122.035 125.521 1.00 37.48  ? 341 TYR A CD2 1 
ATOM   2624 C  CE1 . TYR A 1 341 ? 144.151 124.342 124.460 1.00 36.79  ? 341 TYR A CE1 1 
ATOM   2625 C  CE2 . TYR A 1 341 ? 145.889 123.218 125.627 1.00 36.38  ? 341 TYR A CE2 1 
ATOM   2626 C  CZ  . TYR A 1 341 ? 145.362 124.367 125.095 1.00 36.74  ? 341 TYR A CZ  1 
ATOM   2627 O  OH  . TYR A 1 341 ? 146.046 125.551 125.198 1.00 40.06  ? 341 TYR A OH  1 
ATOM   2628 N  N   . LEU A 1 342 ? 145.463 118.812 123.619 1.00 25.51  ? 342 LEU A N   1 
ATOM   2629 C  CA  . LEU A 1 342 ? 146.900 118.647 123.451 1.00 30.06  ? 342 LEU A CA  1 
ATOM   2630 C  C   . LEU A 1 342 ? 147.269 118.337 122.006 1.00 41.03  ? 342 LEU A C   1 
ATOM   2631 O  O   . LEU A 1 342 ? 148.257 118.869 121.489 1.00 46.72  ? 342 LEU A O   1 
ATOM   2632 C  CB  . LEU A 1 342 ? 147.399 117.549 124.387 1.00 29.13  ? 342 LEU A CB  1 
ATOM   2633 C  CG  . LEU A 1 342 ? 148.731 116.886 124.056 1.00 38.33  ? 342 LEU A CG  1 
ATOM   2634 C  CD1 . LEU A 1 342 ? 149.868 117.705 124.619 1.00 39.08  ? 342 LEU A CD1 1 
ATOM   2635 C  CD2 . LEU A 1 342 ? 148.766 115.470 124.590 1.00 38.66  ? 342 LEU A CD2 1 
ATOM   2636 N  N   . THR A 1 343 ? 146.492 117.490 121.333 1.00 40.83  ? 343 THR A N   1 
ATOM   2637 C  CA  . THR A 1 343 ? 146.895 117.059 119.999 1.00 35.81  ? 343 THR A CA  1 
ATOM   2638 C  C   . THR A 1 343 ? 146.296 117.913 118.887 1.00 44.64  ? 343 THR A C   1 
ATOM   2639 O  O   . THR A 1 343 ? 147.030 118.403 118.025 1.00 52.73  ? 343 THR A O   1 
ATOM   2640 C  CB  . THR A 1 343 ? 146.522 115.596 119.783 1.00 34.67  ? 343 THR A CB  1 
ATOM   2641 O  OG1 . THR A 1 343 ? 145.112 115.490 119.571 1.00 35.21  ? 343 THR A OG1 1 
ATOM   2642 C  CG2 . THR A 1 343 ? 146.913 114.789 120.989 1.00 39.92  ? 343 THR A CG2 1 
ATOM   2643 N  N   . ASP A 1 344 ? 144.976 118.084 118.877 1.00 49.27  ? 344 ASP A N   1 
ATOM   2644 C  CA  . ASP A 1 344 ? 144.332 118.846 117.814 1.00 45.27  ? 344 ASP A CA  1 
ATOM   2645 C  C   . ASP A 1 344 ? 144.864 120.270 117.783 1.00 50.52  ? 344 ASP A C   1 
ATOM   2646 O  O   . ASP A 1 344 ? 144.939 120.939 118.814 1.00 52.82  ? 344 ASP A O   1 
ATOM   2647 C  CB  . ASP A 1 344 ? 142.820 118.855 118.011 1.00 44.67  ? 344 ASP A CB  1 
ATOM   2648 C  CG  . ASP A 1 344 ? 142.064 118.545 116.737 1.00 58.96  ? 344 ASP A CG  1 
ATOM   2649 O  OD1 . ASP A 1 344 ? 142.470 119.039 115.665 1.00 61.12  ? 344 ASP A OD1 1 
ATOM   2650 O  OD2 . ASP A 1 344 ? 141.059 117.809 116.807 1.00 60.63  ? 344 ASP A OD2 1 
ATOM   2651 N  N   . THR A 1 345 ? 145.241 120.731 116.594 1.00 59.77  ? 345 THR A N   1 
ATOM   2652 C  CA  . THR A 1 345 ? 145.828 122.054 116.438 1.00 60.94  ? 345 THR A CA  1 
ATOM   2653 C  C   . THR A 1 345 ? 144.799 123.136 116.152 1.00 61.77  ? 345 THR A C   1 
ATOM   2654 O  O   . THR A 1 345 ? 145.161 124.316 116.105 1.00 63.28  ? 345 THR A O   1 
ATOM   2655 C  CB  . THR A 1 345 ? 146.874 122.041 115.320 1.00 56.69  ? 345 THR A CB  1 
ATOM   2656 O  OG1 . THR A 1 345 ? 147.670 123.228 115.397 1.00 58.70  ? 345 THR A OG1 1 
ATOM   2657 C  CG2 . THR A 1 345 ? 146.198 121.982 113.965 1.00 57.02  ? 345 THR A CG2 1 
ATOM   2658 N  N   . GLN A 1 346 ? 143.534 122.771 115.964 1.00 62.47  ? 346 GLN A N   1 
ATOM   2659 C  CA  . GLN A 1 346 ? 142.465 123.729 115.738 1.00 59.45  ? 346 GLN A CA  1 
ATOM   2660 C  C   . GLN A 1 346 ? 141.581 123.915 116.959 1.00 64.21  ? 346 GLN A C   1 
ATOM   2661 O  O   . GLN A 1 346 ? 140.496 124.490 116.842 1.00 69.51  ? 346 GLN A O   1 
ATOM   2662 C  CB  . GLN A 1 346 ? 141.607 123.298 114.549 1.00 60.59  ? 346 GLN A CB  1 
ATOM   2663 C  CG  . GLN A 1 346 ? 142.391 122.886 113.320 1.00 65.94  ? 346 GLN A CG  1 
ATOM   2664 C  CD  . GLN A 1 346 ? 141.527 122.166 112.306 1.00 69.89  ? 346 GLN A CD  1 
ATOM   2665 O  OE1 . GLN A 1 346 ? 140.529 122.706 111.830 1.00 70.91  ? 346 GLN A OE1 1 
ATOM   2666 N  NE2 . GLN A 1 346 ? 141.903 120.938 111.972 1.00 68.06  ? 346 GLN A NE2 1 
ATOM   2667 N  N   . CYS A 1 347 ? 142.012 123.435 118.126 1.00 51.81  ? 347 CYS A N   1 
ATOM   2668 C  CA  . CYS A 1 347 ? 141.161 123.490 119.309 1.00 51.97  ? 347 CYS A CA  1 
ATOM   2669 C  C   . CYS A 1 347 ? 141.216 124.860 119.973 1.00 52.80  ? 347 CYS A C   1 
ATOM   2670 O  O   . CYS A 1 347 ? 140.189 125.533 120.116 1.00 55.57  ? 347 CYS A O   1 
ATOM   2671 C  CB  . CYS A 1 347 ? 141.559 122.388 120.287 1.00 44.06  ? 347 CYS A CB  1 
ATOM   2672 S  SG  . CYS A 1 347 ? 140.644 120.860 120.034 1.00 50.81  ? 347 CYS A SG  1 
ATOM   2673 N  N   . LYS A 1 348 ? 142.404 125.281 120.399 1.00 43.36  ? 348 LYS A N   1 
ATOM   2674 C  CA  . LYS A 1 348 ? 142.655 126.629 120.904 1.00 46.43  ? 348 LYS A CA  1 
ATOM   2675 C  C   . LYS A 1 348 ? 141.865 126.956 122.168 1.00 44.92  ? 348 LYS A C   1 
ATOM   2676 O  O   . LYS A 1 348 ? 141.734 128.127 122.524 1.00 47.76  ? 348 LYS A O   1 
ATOM   2677 C  CB  . LYS A 1 348 ? 142.371 127.685 119.828 1.00 48.64  ? 348 LYS A CB  1 
ATOM   2678 C  CG  . LYS A 1 348 ? 143.308 127.639 118.635 1.00 48.27  ? 348 LYS A CG  1 
ATOM   2679 C  CD  . LYS A 1 348 ? 144.750 127.800 119.061 1.00 50.84  ? 348 LYS A CD  1 
ATOM   2680 C  CE  . LYS A 1 348 ? 145.687 127.698 117.874 1.00 49.60  ? 348 LYS A CE  1 
ATOM   2681 N  NZ  . LYS A 1 348 ? 145.418 126.484 117.060 1.00 51.46  ? 348 LYS A NZ  1 
ATOM   2682 N  N   . ARG A 1 349 ? 141.321 125.952 122.853 1.00 41.11  ? 349 ARG A N   1 
ATOM   2683 C  CA  . ARG A 1 349 ? 140.715 126.157 124.162 1.00 33.57  ? 349 ARG A CA  1 
ATOM   2684 C  C   . ARG A 1 349 ? 140.582 124.813 124.859 1.00 33.99  ? 349 ARG A C   1 
ATOM   2685 O  O   . ARG A 1 349 ? 140.297 123.803 124.214 1.00 45.02  ? 349 ARG A O   1 
ATOM   2686 C  CB  . ARG A 1 349 ? 139.347 126.838 124.076 1.00 35.48  ? 349 ARG A CB  1 
ATOM   2687 C  CG  . ARG A 1 349 ? 139.043 127.677 125.297 1.00 37.84  ? 349 ARG A CG  1 
ATOM   2688 C  CD  . ARG A 1 349 ? 137.610 128.151 125.352 1.00 37.39  ? 349 ARG A CD  1 
ATOM   2689 N  NE  . ARG A 1 349 ? 137.171 128.319 126.730 1.00 40.99  ? 349 ARG A NE  1 
ATOM   2690 C  CZ  . ARG A 1 349 ? 135.933 128.614 127.093 1.00 41.54  ? 349 ARG A CZ  1 
ATOM   2691 N  NH1 . ARG A 1 349 ? 134.980 128.807 126.201 1.00 39.97  ? 349 ARG A NH1 1 
ATOM   2692 N  NH2 . ARG A 1 349 ? 135.642 128.710 128.385 1.00 38.41  ? 349 ARG A NH2 1 
ATOM   2693 N  N   . VAL A 1 350 ? 140.790 124.812 126.171 1.00 30.52  ? 350 VAL A N   1 
ATOM   2694 C  CA  . VAL A 1 350 ? 140.747 123.592 126.969 1.00 37.86  ? 350 VAL A CA  1 
ATOM   2695 C  C   . VAL A 1 350 ? 139.354 123.443 127.565 1.00 37.15  ? 350 VAL A C   1 
ATOM   2696 O  O   . VAL A 1 350 ? 138.790 124.404 128.100 1.00 45.40  ? 350 VAL A O   1 
ATOM   2697 C  CB  . VAL A 1 350 ? 141.833 123.607 128.059 1.00 30.71  ? 350 VAL A CB  1 
ATOM   2698 C  CG1 . VAL A 1 350 ? 141.683 124.803 128.966 1.00 29.69  ? 350 VAL A CG1 1 
ATOM   2699 C  CG2 . VAL A 1 350 ? 141.804 122.322 128.857 1.00 33.86  ? 350 VAL A CG2 1 
ATOM   2700 N  N   . GLY A 1 351 ? 138.790 122.243 127.452 1.00 27.37  ? 351 GLY A N   1 
ATOM   2701 C  CA  . GLY A 1 351 ? 137.409 122.038 127.837 1.00 27.32  ? 351 GLY A CA  1 
ATOM   2702 C  C   . GLY A 1 351 ? 137.161 122.382 129.290 1.00 28.18  ? 351 GLY A C   1 
ATOM   2703 O  O   . GLY A 1 351 ? 138.063 122.381 130.122 1.00 35.20  ? 351 GLY A O   1 
ATOM   2704 N  N   . THR A 1 352 ? 135.903 122.704 129.590 1.00 27.39  ? 352 THR A N   1 
ATOM   2705 C  CA  . THR A 1 352 ? 135.576 123.194 130.924 1.00 25.51  ? 352 THR A CA  1 
ATOM   2706 C  C   . THR A 1 352 ? 135.704 122.095 131.971 1.00 32.34  ? 352 THR A C   1 
ATOM   2707 O  O   . THR A 1 352 ? 136.103 122.363 133.108 1.00 36.92  ? 352 THR A O   1 
ATOM   2708 C  CB  . THR A 1 352 ? 134.174 123.792 130.941 1.00 28.33  ? 352 THR A CB  1 
ATOM   2709 O  OG1 . THR A 1 352 ? 133.985 124.595 129.772 1.00 36.25  ? 352 THR A OG1 1 
ATOM   2710 C  CG2 . THR A 1 352 ? 134.012 124.674 132.153 1.00 21.73  ? 352 THR A CG2 1 
ATOM   2711 N  N   . GLN A 1 353 ? 135.370 120.855 131.615 1.00 29.56  ? 353 GLN A N   1 
ATOM   2712 C  CA  . GLN A 1 353 ? 135.542 119.758 132.562 1.00 18.19  ? 353 GLN A CA  1 
ATOM   2713 C  C   . GLN A 1 353 ? 137.014 119.530 132.880 1.00 24.26  ? 353 GLN A C   1 
ATOM   2714 O  O   . GLN A 1 353 ? 137.365 119.216 134.020 1.00 31.20  ? 353 GLN A O   1 
ATOM   2715 C  CB  . GLN A 1 353 ? 134.908 118.484 132.017 1.00 19.02  ? 353 GLN A CB  1 
ATOM   2716 C  CG  . GLN A 1 353 ? 135.078 117.286 132.920 1.00 22.03  ? 353 GLN A CG  1 
ATOM   2717 C  CD  . GLN A 1 353 ? 134.131 117.303 134.091 1.00 27.22  ? 353 GLN A CD  1 
ATOM   2718 O  OE1 . GLN A 1 353 ? 134.336 118.027 135.060 1.00 26.87  ? 353 GLN A OE1 1 
ATOM   2719 N  NE2 . GLN A 1 353 ? 133.083 116.501 134.008 1.00 33.40  ? 353 GLN A NE2 1 
ATOM   2720 N  N   . CYS A 1 354 ? 137.889 119.677 131.884 1.00 21.62  ? 354 CYS A N   1 
ATOM   2721 C  CA  . CYS A 1 354 ? 139.323 119.591 132.141 1.00 18.31  ? 354 CYS A CA  1 
ATOM   2722 C  C   . CYS A 1 354 ? 139.784 120.716 133.063 1.00 26.57  ? 354 CYS A C   1 
ATOM   2723 O  O   . CYS A 1 354 ? 140.597 120.496 133.966 1.00 40.02  ? 354 CYS A O   1 
ATOM   2724 C  CB  . CYS A 1 354 ? 140.086 119.620 130.820 1.00 18.74  ? 354 CYS A CB  1 
ATOM   2725 S  SG  . CYS A 1 354 ? 141.826 119.215 130.938 1.00 48.05  ? 354 CYS A SG  1 
ATOM   2726 N  N   . TRP A 1 355 ? 139.260 121.926 132.859 1.00 22.04  ? 355 TRP A N   1 
ATOM   2727 C  CA  . TRP A 1 355 ? 139.575 123.048 133.738 1.00 18.87  ? 355 TRP A CA  1 
ATOM   2728 C  C   . TRP A 1 355 ? 139.153 122.760 135.174 1.00 22.63  ? 355 TRP A C   1 
ATOM   2729 O  O   . TRP A 1 355 ? 139.910 123.012 136.121 1.00 29.08  ? 355 TRP A O   1 
ATOM   2730 C  CB  . TRP A 1 355 ? 138.878 124.303 133.212 1.00 19.33  ? 355 TRP A CB  1 
ATOM   2731 C  CG  . TRP A 1 355 ? 139.358 125.608 133.767 1.00 27.57  ? 355 TRP A CG  1 
ATOM   2732 C  CD1 . TRP A 1 355 ? 140.254 126.457 133.195 1.00 27.96  ? 355 TRP A CD1 1 
ATOM   2733 C  CD2 . TRP A 1 355 ? 138.941 126.232 134.987 1.00 26.51  ? 355 TRP A CD2 1 
ATOM   2734 N  NE1 . TRP A 1 355 ? 140.433 127.560 133.988 1.00 29.06  ? 355 TRP A NE1 1 
ATOM   2735 C  CE2 . TRP A 1 355 ? 139.636 127.445 135.095 1.00 24.81  ? 355 TRP A CE2 1 
ATOM   2736 C  CE3 . TRP A 1 355 ? 138.052 125.875 136.004 1.00 28.16  ? 355 TRP A CE3 1 
ATOM   2737 C  CZ2 . TRP A 1 355 ? 139.473 128.300 136.174 1.00 28.35  ? 355 TRP A CZ2 1 
ATOM   2738 C  CZ3 . TRP A 1 355 ? 137.894 126.726 137.072 1.00 18.08  ? 355 TRP A CZ3 1 
ATOM   2739 C  CH2 . TRP A 1 355 ? 138.597 127.923 137.150 1.00 23.02  ? 355 TRP A CH2 1 
ATOM   2740 N  N   . VAL A 1 356 ? 137.945 122.224 135.352 1.00 23.83  ? 356 VAL A N   1 
ATOM   2741 C  CA  . VAL A 1 356 ? 137.438 121.954 136.692 1.00 19.61  ? 356 VAL A CA  1 
ATOM   2742 C  C   . VAL A 1 356 ? 138.216 120.819 137.346 1.00 29.72  ? 356 VAL A C   1 
ATOM   2743 O  O   . VAL A 1 356 ? 138.508 120.866 138.545 1.00 41.37  ? 356 VAL A O   1 
ATOM   2744 C  CB  . VAL A 1 356 ? 135.930 121.666 136.647 1.00 16.97  ? 356 VAL A CB  1 
ATOM   2745 C  CG1 . VAL A 1 356 ? 135.445 121.255 138.004 1.00 30.31  ? 356 VAL A CG1 1 
ATOM   2746 C  CG2 . VAL A 1 356 ? 135.184 122.894 136.188 1.00 19.06  ? 356 VAL A CG2 1 
ATOM   2747 N  N   . PHE A 1 357 ? 138.574 119.786 136.581 1.00 23.82  ? 357 PHE A N   1 
ATOM   2748 C  CA  . PHE A 1 357 ? 139.423 118.736 137.133 1.00 24.37  ? 357 PHE A CA  1 
ATOM   2749 C  C   . PHE A 1 357 ? 140.775 119.294 137.555 1.00 31.01  ? 357 PHE A C   1 
ATOM   2750 O  O   . PHE A 1 357 ? 141.326 118.893 138.585 1.00 37.22  ? 357 PHE A O   1 
ATOM   2751 C  CB  . PHE A 1 357 ? 139.605 117.609 136.120 1.00 24.60  ? 357 PHE A CB  1 
ATOM   2752 C  CG  . PHE A 1 357 ? 140.403 116.445 136.643 1.00 28.56  ? 357 PHE A CG  1 
ATOM   2753 C  CD1 . PHE A 1 357 ? 139.792 115.429 137.340 1.00 28.53  ? 357 PHE A CD1 1 
ATOM   2754 C  CD2 . PHE A 1 357 ? 141.766 116.372 136.440 1.00 33.20  ? 357 PHE A CD2 1 
ATOM   2755 C  CE1 . PHE A 1 357 ? 140.509 114.361 137.816 1.00 28.54  ? 357 PHE A CE1 1 
ATOM   2756 C  CE2 . PHE A 1 357 ? 142.491 115.305 136.923 1.00 31.61  ? 357 PHE A CE2 1 
ATOM   2757 C  CZ  . PHE A 1 357 ? 141.858 114.300 137.608 1.00 32.17  ? 357 PHE A CZ  1 
ATOM   2758 N  N   . GLY A 1 358 ? 141.326 120.224 136.775 1.00 28.12  ? 358 GLY A N   1 
ATOM   2759 C  CA  . GLY A 1 358 ? 142.596 120.824 137.150 1.00 21.51  ? 358 GLY A CA  1 
ATOM   2760 C  C   . GLY A 1 358 ? 142.515 121.602 138.448 1.00 26.78  ? 358 GLY A C   1 
ATOM   2761 O  O   . GLY A 1 358 ? 143.364 121.447 139.333 1.00 36.83  ? 358 GLY A O   1 
ATOM   2762 N  N   . VAL A 1 359 ? 141.490 122.450 138.589 1.00 26.44  ? 359 VAL A N   1 
ATOM   2763 C  CA  . VAL A 1 359 ? 141.378 123.216 139.829 1.00 21.99  ? 359 VAL A CA  1 
ATOM   2764 C  C   . VAL A 1 359 ? 141.115 122.290 141.006 1.00 29.22  ? 359 VAL A C   1 
ATOM   2765 O  O   . VAL A 1 359 ? 141.640 122.505 142.098 1.00 38.04  ? 359 VAL A O   1 
ATOM   2766 C  CB  . VAL A 1 359 ? 140.311 124.324 139.750 1.00 19.00  ? 359 VAL A CB  1 
ATOM   2767 C  CG1 . VAL A 1 359 ? 140.836 125.527 139.020 1.00 24.81  ? 359 VAL A CG1 1 
ATOM   2768 C  CG2 . VAL A 1 359 ? 139.057 123.828 139.119 1.00 31.07  ? 359 VAL A CG2 1 
ATOM   2769 N  N   . ILE A 1 360 ? 140.302 121.250 140.813 1.00 31.57  ? 360 ILE A N   1 
ATOM   2770 C  CA  . ILE A 1 360 ? 140.039 120.310 141.900 1.00 24.45  ? 360 ILE A CA  1 
ATOM   2771 C  C   . ILE A 1 360 ? 141.330 119.632 142.337 1.00 28.57  ? 360 ILE A C   1 
ATOM   2772 O  O   . ILE A 1 360 ? 141.632 119.540 143.534 1.00 37.26  ? 360 ILE A O   1 
ATOM   2773 C  CB  . ILE A 1 360 ? 138.978 119.282 141.472 1.00 19.27  ? 360 ILE A CB  1 
ATOM   2774 C  CG1 . ILE A 1 360 ? 137.601 119.935 141.402 1.00 16.64  ? 360 ILE A CG1 1 
ATOM   2775 C  CG2 . ILE A 1 360 ? 138.951 118.115 142.429 1.00 24.88  ? 360 ILE A CG2 1 
ATOM   2776 C  CD1 . ILE A 1 360 ? 136.501 118.971 141.087 1.00 20.51  ? 360 ILE A CD1 1 
ATOM   2777 N  N   . GLY A 1 361 ? 142.120 119.159 141.370 1.00 25.79  ? 361 GLY A N   1 
ATOM   2778 C  CA  . GLY A 1 361 ? 143.351 118.463 141.695 1.00 23.00  ? 361 GLY A CA  1 
ATOM   2779 C  C   . GLY A 1 361 ? 144.383 119.341 142.367 1.00 25.81  ? 361 GLY A C   1 
ATOM   2780 O  O   . GLY A 1 361 ? 145.136 118.869 143.222 1.00 28.14  ? 361 GLY A O   1 
ATOM   2781 N  N   . PHE A 1 362 ? 144.453 120.615 141.984 1.00 29.50  ? 362 PHE A N   1 
ATOM   2782 C  CA  . PHE A 1 362 ? 145.398 121.518 142.636 1.00 31.31  ? 362 PHE A CA  1 
ATOM   2783 C  C   . PHE A 1 362 ? 144.905 121.960 144.011 1.00 37.66  ? 362 PHE A C   1 
ATOM   2784 O  O   . PHE A 1 362 ? 145.698 122.077 144.953 1.00 37.93  ? 362 PHE A O   1 
ATOM   2785 C  CB  . PHE A 1 362 ? 145.661 122.728 141.745 1.00 27.19  ? 362 PHE A CB  1 
ATOM   2786 C  CG  . PHE A 1 362 ? 146.679 122.478 140.673 1.00 28.84  ? 362 PHE A CG  1 
ATOM   2787 C  CD1 . PHE A 1 362 ? 148.016 122.341 140.991 1.00 34.63  ? 362 PHE A CD1 1 
ATOM   2788 C  CD2 . PHE A 1 362 ? 146.300 122.380 139.349 1.00 30.06  ? 362 PHE A CD2 1 
ATOM   2789 C  CE1 . PHE A 1 362 ? 148.952 122.110 140.010 1.00 29.61  ? 362 PHE A CE1 1 
ATOM   2790 C  CE2 . PHE A 1 362 ? 147.230 122.149 138.367 1.00 32.96  ? 362 PHE A CE2 1 
ATOM   2791 C  CZ  . PHE A 1 362 ? 148.558 122.015 138.698 1.00 29.22  ? 362 PHE A CZ  1 
ATOM   2792 N  N   . LEU A 1 363 ? 143.598 122.197 144.151 1.00 34.40  ? 363 LEU A N   1 
ATOM   2793 C  CA  . LEU A 1 363 ? 143.051 122.649 145.423 1.00 27.34  ? 363 LEU A CA  1 
ATOM   2794 C  C   . LEU A 1 363 ? 143.087 121.556 146.475 1.00 26.50  ? 363 LEU A C   1 
ATOM   2795 O  O   . LEU A 1 363 ? 143.254 121.854 147.659 1.00 38.11  ? 363 LEU A O   1 
ATOM   2796 C  CB  . LEU A 1 363 ? 141.621 123.144 145.232 1.00 23.46  ? 363 LEU A CB  1 
ATOM   2797 C  CG  . LEU A 1 363 ? 141.482 124.494 144.540 1.00 25.77  ? 363 LEU A CG  1 
ATOM   2798 C  CD1 . LEU A 1 363 ? 140.074 125.000 144.680 1.00 25.05  ? 363 LEU A CD1 1 
ATOM   2799 C  CD2 . LEU A 1 363 ? 142.465 125.475 145.125 1.00 28.61  ? 363 LEU A CD2 1 
ATOM   2800 N  N   . GLU A 1 364 ? 142.923 120.293 146.080 1.00 20.82  ? 364 GLU A N   1 
ATOM   2801 C  CA  . GLU A 1 364 ? 143.069 119.215 147.049 1.00 26.63  ? 364 GLU A CA  1 
ATOM   2802 C  C   . GLU A 1 364 ? 144.489 119.164 147.597 1.00 40.61  ? 364 GLU A C   1 
ATOM   2803 O  O   . GLU A 1 364 ? 144.696 118.945 148.796 1.00 46.99  ? 364 GLU A O   1 
ATOM   2804 C  CB  . GLU A 1 364 ? 142.687 117.883 146.416 1.00 32.62  ? 364 GLU A CB  1 
ATOM   2805 C  CG  . GLU A 1 364 ? 141.259 117.476 146.671 1.00 34.57  ? 364 GLU A CG  1 
ATOM   2806 C  CD  . GLU A 1 364 ? 140.808 116.350 145.772 1.00 47.70  ? 364 GLU A CD  1 
ATOM   2807 O  OE1 . GLU A 1 364 ? 141.521 116.043 144.796 1.00 47.76  ? 364 GLU A OE1 1 
ATOM   2808 O  OE2 . GLU A 1 364 ? 139.741 115.763 146.042 1.00 47.81  ? 364 GLU A OE2 1 
ATOM   2809 N  N   . ALA A 1 365 ? 145.484 119.367 146.732 1.00 34.94  ? 365 ALA A N   1 
ATOM   2810 C  CA  . ALA A 1 365 ? 146.866 119.413 147.193 1.00 28.42  ? 365 ALA A CA  1 
ATOM   2811 C  C   . ALA A 1 365 ? 147.099 120.599 148.118 1.00 32.07  ? 365 ALA A C   1 
ATOM   2812 O  O   . ALA A 1 365 ? 147.804 120.479 149.125 1.00 38.57  ? 365 ALA A O   1 
ATOM   2813 C  CB  . ALA A 1 365 ? 147.818 119.468 146.002 1.00 28.65  ? 365 ALA A CB  1 
ATOM   2814 N  N   . ILE A 1 366 ? 146.524 121.756 147.789 1.00 33.98  ? 366 ILE A N   1 
ATOM   2815 C  CA  . ILE A 1 366 ? 146.670 122.921 148.662 1.00 32.81  ? 366 ILE A CA  1 
ATOM   2816 C  C   . ILE A 1 366 ? 146.026 122.657 150.019 1.00 32.66  ? 366 ILE A C   1 
ATOM   2817 O  O   . ILE A 1 366 ? 146.557 123.053 151.062 1.00 39.37  ? 366 ILE A O   1 
ATOM   2818 C  CB  . ILE A 1 366 ? 146.089 124.178 147.991 1.00 31.36  ? 366 ILE A CB  1 
ATOM   2819 C  CG1 . ILE A 1 366 ? 146.825 124.477 146.690 1.00 30.74  ? 366 ILE A CG1 1 
ATOM   2820 C  CG2 . ILE A 1 366 ? 146.210 125.370 148.907 1.00 38.07  ? 366 ILE A CG2 1 
ATOM   2821 C  CD1 . ILE A 1 366 ? 146.210 125.593 145.901 1.00 36.39  ? 366 ILE A CD1 1 
ATOM   2822 N  N   . VAL A 1 367 ? 144.874 121.984 150.026 1.00 36.39  ? 367 VAL A N   1 
ATOM   2823 C  CA  . VAL A 1 367 ? 144.207 121.624 151.276 1.00 35.74  ? 367 VAL A CA  1 
ATOM   2824 C  C   . VAL A 1 367 ? 145.086 120.692 152.099 1.00 36.24  ? 367 VAL A C   1 
ATOM   2825 O  O   . VAL A 1 367 ? 145.232 120.862 153.316 1.00 42.06  ? 367 VAL A O   1 
ATOM   2826 C  CB  . VAL A 1 367 ? 142.835 120.988 150.979 1.00 30.37  ? 367 VAL A CB  1 
ATOM   2827 C  CG1 . VAL A 1 367 ? 142.418 120.075 152.103 1.00 33.59  ? 367 VAL A CG1 1 
ATOM   2828 C  CG2 . VAL A 1 367 ? 141.787 122.050 150.753 1.00 31.03  ? 367 VAL A CG2 1 
ATOM   2829 N  N   . CYS A 1 368 ? 145.684 119.693 151.447 1.00 42.56  ? 368 CYS A N   1 
ATOM   2830 C  CA  . CYS A 1 368 ? 146.545 118.751 152.156 1.00 42.71  ? 368 CYS A CA  1 
ATOM   2831 C  C   . CYS A 1 368 ? 147.782 119.440 152.718 1.00 42.33  ? 368 CYS A C   1 
ATOM   2832 O  O   . CYS A 1 368 ? 148.260 119.084 153.799 1.00 44.91  ? 368 CYS A O   1 
ATOM   2833 C  CB  . CYS A 1 368 ? 146.947 117.606 151.228 1.00 42.45  ? 368 CYS A CB  1 
ATOM   2834 S  SG  . CYS A 1 368 ? 145.590 116.543 150.726 1.00 51.82  ? 368 CYS A SG  1 
ATOM   2835 N  N   . ILE A 1 369 ? 148.329 120.414 151.990 1.00 39.57  ? 369 ILE A N   1 
ATOM   2836 C  CA  . ILE A 1 369 ? 149.489 121.143 152.497 1.00 36.62  ? 369 ILE A CA  1 
ATOM   2837 C  C   . ILE A 1 369 ? 149.095 122.034 153.669 1.00 43.77  ? 369 ILE A C   1 
ATOM   2838 O  O   . ILE A 1 369 ? 149.837 122.152 154.650 1.00 48.55  ? 369 ILE A O   1 
ATOM   2839 C  CB  . ILE A 1 369 ? 150.155 121.957 151.374 1.00 31.97  ? 369 ILE A CB  1 
ATOM   2840 C  CG1 . ILE A 1 369 ? 150.698 121.032 150.292 1.00 34.52  ? 369 ILE A CG1 1 
ATOM   2841 C  CG2 . ILE A 1 369 ? 151.286 122.783 151.928 1.00 38.25  ? 369 ILE A CG2 1 
ATOM   2842 C  CD1 . ILE A 1 369 ? 151.183 121.759 149.071 1.00 38.76  ? 369 ILE A CD1 1 
ATOM   2843 N  N   . LYS A 1 370 ? 147.929 122.677 153.590 1.00 43.32  ? 370 LYS A N   1 
ATOM   2844 C  CA  . LYS A 1 370 ? 147.517 123.589 154.652 1.00 40.79  ? 370 LYS A CA  1 
ATOM   2845 C  C   . LYS A 1 370 ? 147.195 122.839 155.938 1.00 38.53  ? 370 LYS A C   1 
ATOM   2846 O  O   . LYS A 1 370 ? 147.668 123.211 157.018 1.00 42.03  ? 370 LYS A O   1 
ATOM   2847 C  CB  . LYS A 1 370 ? 146.316 124.418 154.198 1.00 39.71  ? 370 LYS A CB  1 
ATOM   2848 C  CG  . LYS A 1 370 ? 145.767 125.343 155.268 1.00 38.68  ? 370 LYS A CG  1 
ATOM   2849 C  CD  . LYS A 1 370 ? 144.313 125.684 155.011 1.00 38.76  ? 370 LYS A CD  1 
ATOM   2850 C  CE  . LYS A 1 370 ? 143.727 126.514 156.140 1.00 37.55  ? 370 LYS A CE  1 
ATOM   2851 N  NZ  . LYS A 1 370 ? 144.226 127.910 156.140 1.00 35.19  ? 370 LYS A NZ  1 
ATOM   2852 N  N   . PHE A 1 371 ? 146.391 121.780 155.849 1.00 41.12  ? 371 PHE A N   1 
ATOM   2853 C  CA  . PHE A 1 371 ? 145.987 121.043 157.038 1.00 44.41  ? 371 PHE A CA  1 
ATOM   2854 C  C   . PHE A 1 371 ? 146.969 119.948 157.427 1.00 50.17  ? 371 PHE A C   1 
ATOM   2855 O  O   . PHE A 1 371 ? 146.816 119.355 158.500 1.00 53.02  ? 371 PHE A O   1 
ATOM   2856 C  CB  . PHE A 1 371 ? 144.599 120.427 156.839 1.00 42.65  ? 371 PHE A CB  1 
ATOM   2857 C  CG  . PHE A 1 371 ? 143.512 121.440 156.637 1.00 44.35  ? 371 PHE A CG  1 
ATOM   2858 C  CD1 . PHE A 1 371 ? 143.373 122.504 157.503 1.00 46.09  ? 371 PHE A CD1 1 
ATOM   2859 C  CD2 . PHE A 1 371 ? 142.630 121.329 155.581 1.00 42.58  ? 371 PHE A CD2 1 
ATOM   2860 C  CE1 . PHE A 1 371 ? 142.381 123.435 157.318 1.00 40.58  ? 371 PHE A CE1 1 
ATOM   2861 C  CE2 . PHE A 1 371 ? 141.636 122.262 155.395 1.00 45.84  ? 371 PHE A CE2 1 
ATOM   2862 C  CZ  . PHE A 1 371 ? 141.514 123.315 156.264 1.00 40.57  ? 371 PHE A CZ  1 
ATOM   2863 N  N   . GLY A 1 372 ? 147.965 119.668 156.595 1.00 53.87  ? 372 GLY A N   1 
ATOM   2864 C  CA  . GLY A 1 372 ? 148.938 118.638 156.897 1.00 54.85  ? 372 GLY A CA  1 
ATOM   2865 C  C   . GLY A 1 372 ? 150.249 119.215 157.379 1.00 57.11  ? 372 GLY A C   1 
ATOM   2866 O  O   . GLY A 1 372 ? 151.311 118.613 157.199 1.00 59.76  ? 372 GLY A O   1 
ATOM   2867 N  N   . GLN A 1 373 ? 150.183 120.399 157.984 1.00 63.12  ? 373 GLN A N   1 
ATOM   2868 C  CA  . GLN A 1 373 ? 151.377 121.065 158.484 1.00 63.84  ? 373 GLN A CA  1 
ATOM   2869 C  C   . GLN A 1 373 ? 151.980 120.362 159.692 1.00 68.14  ? 373 GLN A C   1 
ATOM   2870 O  O   . GLN A 1 373 ? 153.110 120.686 160.073 1.00 70.60  ? 373 GLN A O   1 
ATOM   2871 C  CB  . GLN A 1 373 ? 151.044 122.515 158.848 1.00 65.72  ? 373 GLN A CB  1 
ATOM   2872 C  CG  . GLN A 1 373 ? 150.908 123.457 157.660 1.00 62.12  ? 373 GLN A CG  1 
ATOM   2873 C  CD  . GLN A 1 373 ? 152.176 123.565 156.843 1.00 65.81  ? 373 GLN A CD  1 
ATOM   2874 O  OE1 . GLN A 1 373 ? 152.439 122.741 155.969 1.00 64.65  ? 373 GLN A OE1 1 
ATOM   2875 N  NE2 . GLN A 1 373 ? 152.971 124.590 157.122 1.00 69.39  ? 373 GLN A NE2 1 
ATOM   2876 N  N   . ASP A 1 374 ? 151.266 119.413 160.297 1.00 76.52  ? 374 ASP A N   1 
ATOM   2877 C  CA  . ASP A 1 374 ? 151.676 118.810 161.559 1.00 78.52  ? 374 ASP A CA  1 
ATOM   2878 C  C   . ASP A 1 374 ? 152.243 117.403 161.415 1.00 76.78  ? 374 ASP A C   1 
ATOM   2879 O  O   . ASP A 1 374 ? 153.167 117.042 162.148 1.00 78.85  ? 374 ASP A O   1 
ATOM   2880 C  CB  . ASP A 1 374 ? 150.494 118.782 162.532 1.00 76.59  ? 374 ASP A CB  1 
ATOM   2881 C  CG  . ASP A 1 374 ? 149.319 117.986 161.999 1.00 78.68  ? 374 ASP A CG  1 
ATOM   2882 O  OD1 . ASP A 1 374 ? 149.292 117.704 160.782 1.00 76.62  ? 374 ASP A OD1 1 
ATOM   2883 O  OD2 . ASP A 1 374 ? 148.421 117.644 162.796 1.00 77.86  ? 374 ASP A OD2 1 
ATOM   2884 N  N   . LEU A 1 375 ? 151.724 116.592 160.494 1.00 73.37  ? 375 LEU A N   1 
ATOM   2885 C  CA  . LEU A 1 375 ? 152.159 115.203 160.396 1.00 77.22  ? 375 LEU A CA  1 
ATOM   2886 C  C   . LEU A 1 375 ? 153.496 115.035 159.679 1.00 79.90  ? 375 LEU A C   1 
ATOM   2887 O  O   . LEU A 1 375 ? 153.858 113.904 159.339 1.00 78.30  ? 375 LEU A O   1 
ATOM   2888 C  CB  . LEU A 1 375 ? 151.084 114.351 159.713 1.00 80.85  ? 375 LEU A CB  1 
ATOM   2889 C  CG  . LEU A 1 375 ? 150.300 114.856 158.502 1.00 79.81  ? 375 LEU A CG  1 
ATOM   2890 C  CD1 . LEU A 1 375 ? 151.160 114.924 157.263 1.00 76.19  ? 375 LEU A CD1 1 
ATOM   2891 C  CD2 . LEU A 1 375 ? 149.116 113.940 158.265 1.00 76.78  ? 375 LEU A CD2 1 
ATOM   2892 N  N   . PHE A 1 376 ? 154.228 116.118 159.437 1.00 83.47  ? 376 PHE A N   1 
ATOM   2893 C  CA  . PHE A 1 376 ? 155.599 116.054 158.955 1.00 85.43  ? 376 PHE A CA  1 
ATOM   2894 C  C   . PHE A 1 376 ? 156.496 116.879 159.866 1.00 86.05  ? 376 PHE A C   1 
ATOM   2895 O  O   . PHE A 1 376 ? 156.143 117.997 160.252 1.00 84.41  ? 376 PHE A O   1 
ATOM   2896 C  CB  . PHE A 1 376 ? 155.726 116.566 157.517 1.00 85.32  ? 376 PHE A CB  1 
ATOM   2897 C  CG  . PHE A 1 376 ? 154.960 115.759 156.509 1.00 86.89  ? 376 PHE A CG  1 
ATOM   2898 C  CD1 . PHE A 1 376 ? 155.178 114.397 156.380 1.00 85.19  ? 376 PHE A CD1 1 
ATOM   2899 C  CD2 . PHE A 1 376 ? 154.050 116.371 155.663 1.00 87.87  ? 376 PHE A CD2 1 
ATOM   2900 C  CE1 . PHE A 1 376 ? 154.488 113.653 155.444 1.00 84.19  ? 376 PHE A CE1 1 
ATOM   2901 C  CE2 . PHE A 1 376 ? 153.358 115.633 154.721 1.00 88.29  ? 376 PHE A CE2 1 
ATOM   2902 C  CZ  . PHE A 1 376 ? 153.577 114.271 154.614 1.00 86.84  ? 376 PHE A CZ  1 
ATOM   2903 N  N   . SER A 1 377 ? 157.651 116.318 160.217 1.00 84.35  ? 377 SER A N   1 
ATOM   2904 C  CA  . SER A 1 377 ? 158.661 117.034 160.986 1.00 83.02  ? 377 SER A CA  1 
ATOM   2905 C  C   . SER A 1 377 ? 159.946 117.245 160.203 1.00 85.06  ? 377 SER A C   1 
ATOM   2906 O  O   . SER A 1 377 ? 160.381 118.388 160.027 1.00 83.02  ? 377 SER A O   1 
ATOM   2907 C  CB  . SER A 1 377 ? 158.957 116.277 162.289 1.00 81.40  ? 377 SER A CB  1 
ATOM   2908 O  OG  . SER A 1 377 ? 159.266 114.919 162.028 1.00 82.37  ? 377 SER A OG  1 
ATOM   2909 N  N   . LYS A 1 378 ? 160.564 116.166 159.720 1.00 87.83  ? 378 LYS A N   1 
ATOM   2910 C  CA  . LYS A 1 378 ? 161.763 116.244 158.896 1.00 85.06  ? 378 LYS A CA  1 
ATOM   2911 C  C   . LYS A 1 378 ? 161.591 115.483 157.589 1.00 86.14  ? 378 LYS A C   1 
ATOM   2912 O  O   . LYS A 1 378 ? 162.592 115.127 156.957 1.00 85.88  ? 378 LYS A O   1 
ATOM   2913 C  CB  . LYS A 1 378 ? 162.990 115.706 159.645 1.00 85.66  ? 378 LYS A CB  1 
ATOM   2914 C  CG  . LYS A 1 378 ? 163.415 116.520 160.861 1.00 87.41  ? 378 LYS A CG  1 
ATOM   2915 C  CD  . LYS A 1 378 ? 162.643 116.119 162.107 1.00 87.78  ? 378 LYS A CD  1 
ATOM   2916 C  CE  . LYS A 1 378 ? 162.864 117.107 163.237 1.00 86.69  ? 378 LYS A CE  1 
ATOM   2917 N  NZ  . LYS A 1 378 ? 161.708 117.135 164.175 1.00 86.71  ? 378 LYS A NZ  1 
ATOM   2918 N  N   . THR A 1 379 ? 160.353 115.220 157.180 1.00 84.69  ? 379 THR A N   1 
ATOM   2919 C  CA  . THR A 1 379 ? 160.093 114.407 156.002 1.00 85.07  ? 379 THR A CA  1 
ATOM   2920 C  C   . THR A 1 379 ? 160.565 115.115 154.738 1.00 85.84  ? 379 THR A C   1 
ATOM   2921 O  O   . THR A 1 379 ? 160.620 116.346 154.666 1.00 81.62  ? 379 THR A O   1 
ATOM   2922 C  CB  . THR A 1 379 ? 158.605 114.086 155.907 1.00 83.45  ? 379 THR A CB  1 
ATOM   2923 O  OG1 . THR A 1 379 ? 158.074 113.937 157.229 1.00 83.47  ? 379 THR A OG1 1 
ATOM   2924 C  CG2 . THR A 1 379 ? 158.384 112.793 155.136 1.00 86.12  ? 379 THR A CG2 1 
ATOM   2925 N  N   . GLN A 1 380 ? 160.899 114.315 153.729 1.00 79.97  ? 380 GLN A N   1 
ATOM   2926 C  CA  . GLN A 1 380 ? 161.609 114.782 152.548 1.00 74.55  ? 380 GLN A CA  1 
ATOM   2927 C  C   . GLN A 1 380 ? 160.656 114.969 151.375 1.00 77.73  ? 380 GLN A C   1 
ATOM   2928 O  O   . GLN A 1 380 ? 159.832 114.095 151.086 1.00 72.57  ? 380 GLN A O   1 
ATOM   2929 C  CB  . GLN A 1 380 ? 162.710 113.793 152.169 1.00 69.84  ? 380 GLN A CB  1 
ATOM   2930 C  CG  . GLN A 1 380 ? 163.845 113.732 153.169 1.00 77.16  ? 380 GLN A CG  1 
ATOM   2931 C  CD  . GLN A 1 380 ? 163.713 112.565 154.126 1.00 78.34  ? 380 GLN A CD  1 
ATOM   2932 O  OE1 . GLN A 1 380 ? 162.801 111.748 154.004 1.00 75.98  ? 380 GLN A OE1 1 
ATOM   2933 N  NE2 . GLN A 1 380 ? 164.628 112.479 155.085 1.00 75.00  ? 380 GLN A NE2 1 
ATOM   2934 N  N   . ILE A 1 381 ? 160.773 116.123 150.710 1.00 73.30  ? 381 ILE A N   1 
ATOM   2935 C  CA  . ILE A 1 381 ? 160.191 116.317 149.384 1.00 65.68  ? 381 ILE A CA  1 
ATOM   2936 C  C   . ILE A 1 381 ? 161.102 115.794 148.289 1.00 64.92  ? 381 ILE A C   1 
ATOM   2937 O  O   . ILE A 1 381 ? 160.712 115.794 147.115 1.00 64.68  ? 381 ILE A O   1 
ATOM   2938 C  CB  . ILE A 1 381 ? 159.887 117.810 149.146 1.00 64.91  ? 381 ILE A CB  1 
ATOM   2939 C  CG1 . ILE A 1 381 ? 158.771 117.978 148.111 1.00 70.14  ? 381 ILE A CG1 1 
ATOM   2940 C  CG2 . ILE A 1 381 ? 161.147 118.546 148.724 1.00 61.10  ? 381 ILE A CG2 1 
ATOM   2941 C  CD1 . ILE A 1 381 ? 158.389 119.416 147.841 1.00 66.94  ? 381 ILE A CD1 1 
ATOM   2942 N  N   . LEU A 1 382 ? 162.307 115.339 148.643 1.00 67.89  ? 382 LEU A N   1 
ATOM   2943 C  CA  . LEU A 1 382 ? 163.270 114.896 147.641 1.00 65.49  ? 382 LEU A CA  1 
ATOM   2944 C  C   . LEU A 1 382 ? 162.737 113.716 146.844 1.00 64.02  ? 382 LEU A C   1 
ATOM   2945 O  O   . LEU A 1 382 ? 163.003 113.598 145.643 1.00 63.41  ? 382 LEU A O   1 
ATOM   2946 C  CB  . LEU A 1 382 ? 164.598 114.531 148.305 1.00 63.27  ? 382 LEU A CB  1 
ATOM   2947 C  CG  . LEU A 1 382 ? 165.550 115.661 148.710 1.00 65.27  ? 382 LEU A CG  1 
ATOM   2948 C  CD1 . LEU A 1 382 ? 165.970 116.462 147.487 1.00 64.02  ? 382 LEU A CD1 1 
ATOM   2949 C  CD2 . LEU A 1 382 ? 164.962 116.570 149.781 1.00 67.31  ? 382 LEU A CD2 1 
ATOM   2950 N  N   . TYR A 1 383 ? 161.991 112.824 147.498 1.00 60.26  ? 383 TYR A N   1 
ATOM   2951 C  CA  . TYR A 1 383 ? 161.379 111.714 146.779 1.00 58.82  ? 383 TYR A CA  1 
ATOM   2952 C  C   . TYR A 1 383 ? 160.401 112.220 145.728 1.00 64.05  ? 383 TYR A C   1 
ATOM   2953 O  O   . TYR A 1 383 ? 160.355 111.697 144.609 1.00 67.20  ? 383 TYR A O   1 
ATOM   2954 C  CB  . TYR A 1 383 ? 160.676 110.781 147.757 1.00 56.68  ? 383 TYR A CB  1 
ATOM   2955 C  CG  . TYR A 1 383 ? 160.354 109.429 147.179 1.00 57.20  ? 383 TYR A CG  1 
ATOM   2956 C  CD1 . TYR A 1 383 ? 161.304 108.419 147.167 1.00 59.33  ? 383 TYR A CD1 1 
ATOM   2957 C  CD2 . TYR A 1 383 ? 159.106 109.162 146.645 1.00 54.68  ? 383 TYR A CD2 1 
ATOM   2958 C  CE1 . TYR A 1 383 ? 161.019 107.183 146.644 1.00 59.06  ? 383 TYR A CE1 1 
ATOM   2959 C  CE2 . TYR A 1 383 ? 158.814 107.929 146.118 1.00 56.76  ? 383 TYR A CE2 1 
ATOM   2960 C  CZ  . TYR A 1 383 ? 159.773 106.943 146.122 1.00 58.59  ? 383 TYR A CZ  1 
ATOM   2961 O  OH  . TYR A 1 383 ? 159.488 105.706 145.598 1.00 60.83  ? 383 TYR A OH  1 
ATOM   2962 N  N   . VAL A 1 384 ? 159.607 113.236 146.071 1.00 60.83  ? 384 VAL A N   1 
ATOM   2963 C  CA  . VAL A 1 384 ? 158.736 113.866 145.084 1.00 59.19  ? 384 VAL A CA  1 
ATOM   2964 C  C   . VAL A 1 384 ? 159.566 114.500 143.975 1.00 57.11  ? 384 VAL A C   1 
ATOM   2965 O  O   . VAL A 1 384 ? 159.236 114.387 142.790 1.00 55.39  ? 384 VAL A O   1 
ATOM   2966 C  CB  . VAL A 1 384 ? 157.808 114.886 145.767 1.00 56.52  ? 384 VAL A CB  1 
ATOM   2967 C  CG1 . VAL A 1 384 ? 157.272 115.873 144.760 1.00 61.70  ? 384 VAL A CG1 1 
ATOM   2968 C  CG2 . VAL A 1 384 ? 156.660 114.168 146.457 1.00 48.79  ? 384 VAL A CG2 1 
ATOM   2969 N  N   . VAL A 1 385 ? 160.661 115.170 144.338 1.00 62.29  ? 385 VAL A N   1 
ATOM   2970 C  CA  . VAL A 1 385 ? 161.578 115.690 143.326 1.00 63.72  ? 385 VAL A CA  1 
ATOM   2971 C  C   . VAL A 1 385 ? 162.189 114.546 142.527 1.00 62.48  ? 385 VAL A C   1 
ATOM   2972 O  O   . VAL A 1 385 ? 162.318 114.626 141.300 1.00 67.46  ? 385 VAL A O   1 
ATOM   2973 C  CB  . VAL A 1 385 ? 162.661 116.568 143.982 1.00 63.49  ? 385 VAL A CB  1 
ATOM   2974 C  CG1 . VAL A 1 385 ? 163.750 116.909 142.981 1.00 61.93  ? 385 VAL A CG1 1 
ATOM   2975 C  CG2 . VAL A 1 385 ? 162.047 117.834 144.543 1.00 62.78  ? 385 VAL A CG2 1 
ATOM   2976 N  N   . LEU A 1 386 ? 162.583 113.468 143.207 1.00 57.39  ? 386 LEU A N   1 
ATOM   2977 C  CA  . LEU A 1 386 ? 163.140 112.317 142.504 1.00 59.82  ? 386 LEU A CA  1 
ATOM   2978 C  C   . LEU A 1 386 ? 162.096 111.667 141.608 1.00 59.25  ? 386 LEU A C   1 
ATOM   2979 O  O   . LEU A 1 386 ? 162.409 111.232 140.495 1.00 62.48  ? 386 LEU A O   1 
ATOM   2980 C  CB  . LEU A 1 386 ? 163.701 111.310 143.507 1.00 64.13  ? 386 LEU A CB  1 
ATOM   2981 C  CG  . LEU A 1 386 ? 165.167 111.518 143.894 1.00 65.61  ? 386 LEU A CG  1 
ATOM   2982 C  CD1 . LEU A 1 386 ? 165.708 110.316 144.648 1.00 63.04  ? 386 LEU A CD1 1 
ATOM   2983 C  CD2 . LEU A 1 386 ? 166.018 111.815 142.668 1.00 63.96  ? 386 LEU A CD2 1 
ATOM   2984 N  N   . TRP A 1 387 ? 160.851 111.580 142.083 1.00 58.91  ? 387 TRP A N   1 
ATOM   2985 C  CA  . TRP A 1 387 ? 159.752 111.130 141.233 1.00 62.08  ? 387 TRP A CA  1 
ATOM   2986 C  C   . TRP A 1 387 ? 159.586 112.008 139.998 1.00 62.17  ? 387 TRP A C   1 
ATOM   2987 O  O   . TRP A 1 387 ? 159.222 111.507 138.929 1.00 59.88  ? 387 TRP A O   1 
ATOM   2988 C  CB  . TRP A 1 387 ? 158.458 111.078 142.049 1.00 60.01  ? 387 TRP A CB  1 
ATOM   2989 C  CG  . TRP A 1 387 ? 157.230 111.380 141.255 1.00 64.36  ? 387 TRP A CG  1 
ATOM   2990 C  CD1 . TRP A 1 387 ? 156.734 110.675 140.203 1.00 64.82  ? 387 TRP A CD1 1 
ATOM   2991 C  CD2 . TRP A 1 387 ? 156.327 112.475 141.466 1.00 67.41  ? 387 TRP A CD2 1 
ATOM   2992 N  NE1 . TRP A 1 387 ? 155.592 111.277 139.729 1.00 65.60  ? 387 TRP A NE1 1 
ATOM   2993 C  CE2 . TRP A 1 387 ? 155.318 112.379 140.495 1.00 66.06  ? 387 TRP A CE2 1 
ATOM   2994 C  CE3 . TRP A 1 387 ? 156.277 113.527 142.383 1.00 68.29  ? 387 TRP A CE3 1 
ATOM   2995 C  CZ2 . TRP A 1 387 ? 154.274 113.298 140.411 1.00 63.00  ? 387 TRP A CZ2 1 
ATOM   2996 C  CZ3 . TRP A 1 387 ? 155.236 114.439 142.296 1.00 62.88  ? 387 TRP A CZ3 1 
ATOM   2997 C  CH2 . TRP A 1 387 ? 154.252 114.316 141.321 1.00 59.57  ? 387 TRP A CH2 1 
ATOM   2998 N  N   . LEU A 1 388 ? 159.857 113.308 140.115 1.00 60.74  ? 388 LEU A N   1 
ATOM   2999 C  CA  . LEU A 1 388 ? 159.739 114.192 138.961 1.00 58.20  ? 388 LEU A CA  1 
ATOM   3000 C  C   . LEU A 1 388 ? 160.704 113.797 137.851 1.00 59.50  ? 388 LEU A C   1 
ATOM   3001 O  O   . LEU A 1 388 ? 160.341 113.813 136.670 1.00 61.88  ? 388 LEU A O   1 
ATOM   3002 C  CB  . LEU A 1 388 ? 159.984 115.639 139.381 1.00 61.11  ? 388 LEU A CB  1 
ATOM   3003 C  CG  . LEU A 1 388 ? 158.756 116.532 139.539 1.00 65.61  ? 388 LEU A CG  1 
ATOM   3004 C  CD1 . LEU A 1 388 ? 158.151 116.809 138.195 1.00 60.96  ? 388 LEU A CD1 1 
ATOM   3005 C  CD2 . LEU A 1 388 ? 157.735 115.900 140.442 1.00 63.88  ? 388 LEU A CD2 1 
ATOM   3006 N  N   . LEU A 1 389 ? 161.945 113.458 138.207 1.00 63.52  ? 389 LEU A N   1 
ATOM   3007 C  CA  . LEU A 1 389 ? 162.925 113.079 137.193 1.00 62.51  ? 389 LEU A CA  1 
ATOM   3008 C  C   . LEU A 1 389 ? 162.615 111.711 136.600 1.00 63.60  ? 389 LEU A C   1 
ATOM   3009 O  O   . LEU A 1 389 ? 162.681 111.530 135.379 1.00 67.31  ? 389 LEU A O   1 
ATOM   3010 C  CB  . LEU A 1 389 ? 164.332 113.095 137.786 1.00 62.23  ? 389 LEU A CB  1 
ATOM   3011 C  CG  . LEU A 1 389 ? 165.447 112.731 136.806 1.00 63.92  ? 389 LEU A CG  1 
ATOM   3012 C  CD1 . LEU A 1 389 ? 165.766 113.904 135.895 1.00 59.15  ? 389 LEU A CD1 1 
ATOM   3013 C  CD2 . LEU A 1 389 ? 166.690 112.262 137.540 1.00 64.74  ? 389 LEU A CD2 1 
ATOM   3014 N  N   . CYS A 1 390 ? 162.264 110.739 137.443 1.00 66.15  ? 390 CYS A N   1 
ATOM   3015 C  CA  . CYS A 1 390 ? 161.983 109.391 136.964 1.00 64.54  ? 390 CYS A CA  1 
ATOM   3016 C  C   . CYS A 1 390 ? 160.725 109.313 136.115 1.00 70.26  ? 390 CYS A C   1 
ATOM   3017 O  O   . CYS A 1 390 ? 160.496 108.278 135.482 1.00 77.79  ? 390 CYS A O   1 
ATOM   3018 C  CB  . CYS A 1 390 ? 161.867 108.428 138.142 1.00 68.58  ? 390 CYS A CB  1 
ATOM   3019 S  SG  . CYS A 1 390 ? 163.293 108.447 139.243 1.00 86.30  ? 390 CYS A SG  1 
ATOM   3020 N  N   . VAL A 1 391 ? 159.902 110.361 136.092 1.00 63.93  ? 391 VAL A N   1 
ATOM   3021 C  CA  . VAL A 1 391 ? 158.784 110.403 135.156 1.00 63.89  ? 391 VAL A CA  1 
ATOM   3022 C  C   . VAL A 1 391 ? 159.248 110.909 133.796 1.00 62.61  ? 391 VAL A C   1 
ATOM   3023 O  O   . VAL A 1 391 ? 158.891 110.349 132.754 1.00 60.83  ? 391 VAL A O   1 
ATOM   3024 C  CB  . VAL A 1 391 ? 157.638 111.260 135.727 1.00 61.36  ? 391 VAL A CB  1 
ATOM   3025 C  CG1 . VAL A 1 391 ? 156.764 111.790 134.617 1.00 56.94  ? 391 VAL A CG1 1 
ATOM   3026 C  CG2 . VAL A 1 391 ? 156.805 110.447 136.689 1.00 58.99  ? 391 VAL A CG2 1 
ATOM   3027 N  N   . ALA A 1 392 ? 160.061 111.968 133.783 1.00 62.29  ? 392 ALA A N   1 
ATOM   3028 C  CA  . ALA A 1 392 ? 160.628 112.447 132.527 1.00 61.11  ? 392 ALA A CA  1 
ATOM   3029 C  C   . ALA A 1 392 ? 161.576 111.419 131.927 1.00 66.27  ? 392 ALA A C   1 
ATOM   3030 O  O   . ALA A 1 392 ? 161.649 111.271 130.702 1.00 70.42  ? 392 ALA A O   1 
ATOM   3031 C  CB  . ALA A 1 392 ? 161.349 113.776 132.742 1.00 58.88  ? 392 ALA A CB  1 
ATOM   3032 N  N   . PHE A 1 393 ? 162.319 110.708 132.777 1.00 71.60  ? 393 PHE A N   1 
ATOM   3033 C  CA  . PHE A 1 393 ? 163.153 109.608 132.304 1.00 70.02  ? 393 PHE A CA  1 
ATOM   3034 C  C   . PHE A 1 393 ? 162.323 108.580 131.544 1.00 69.70  ? 393 PHE A C   1 
ATOM   3035 O  O   . PHE A 1 393 ? 162.798 107.979 130.576 1.00 71.96  ? 393 PHE A O   1 
ATOM   3036 C  CB  . PHE A 1 393 ? 163.868 108.960 133.492 1.00 73.99  ? 393 PHE A CB  1 
ATOM   3037 C  CG  . PHE A 1 393 ? 164.667 107.732 133.144 1.00 78.98  ? 393 PHE A CG  1 
ATOM   3038 C  CD1 . PHE A 1 393 ? 165.390 107.654 131.964 1.00 77.03  ? 393 PHE A CD1 1 
ATOM   3039 C  CD2 . PHE A 1 393 ? 164.680 106.643 134.000 1.00 78.13  ? 393 PHE A CD2 1 
ATOM   3040 C  CE1 . PHE A 1 393 ? 166.113 106.518 131.650 1.00 73.84  ? 393 PHE A CE1 1 
ATOM   3041 C  CE2 . PHE A 1 393 ? 165.400 105.507 133.692 1.00 75.42  ? 393 PHE A CE2 1 
ATOM   3042 C  CZ  . PHE A 1 393 ? 166.118 105.444 132.516 1.00 74.09  ? 393 PHE A CZ  1 
ATOM   3043 N  N   . THR A 1 394 ? 161.073 108.376 131.954 1.00 69.41  ? 394 THR A N   1 
ATOM   3044 C  CA  . THR A 1 394 ? 160.233 107.371 131.320 1.00 70.19  ? 394 THR A CA  1 
ATOM   3045 C  C   . THR A 1 394 ? 159.397 107.922 130.169 1.00 69.80  ? 394 THR A C   1 
ATOM   3046 O  O   . THR A 1 394 ? 158.918 107.137 129.344 1.00 70.16  ? 394 THR A O   1 
ATOM   3047 C  CB  . THR A 1 394 ? 159.317 106.719 132.357 1.00 69.05  ? 394 THR A CB  1 
ATOM   3048 O  OG1 . THR A 1 394 ? 160.027 106.571 133.591 1.00 68.32  ? 394 THR A OG1 1 
ATOM   3049 C  CG2 . THR A 1 394 ? 158.907 105.340 131.885 1.00 70.92  ? 394 THR A CG2 1 
ATOM   3050 N  N   . THR A 1 395 ? 159.197 109.239 130.089 1.00 70.84  ? 395 THR A N   1 
ATOM   3051 C  CA  . THR A 1 395 ? 158.633 109.806 128.867 1.00 71.65  ? 395 THR A CA  1 
ATOM   3052 C  C   . THR A 1 395 ? 159.665 109.807 127.749 1.00 72.83  ? 395 THR A C   1 
ATOM   3053 O  O   . THR A 1 395 ? 159.361 109.422 126.615 1.00 76.99  ? 395 THR A O   1 
ATOM   3054 C  CB  . THR A 1 395 ? 158.112 111.224 129.113 1.00 71.88  ? 395 THR A CB  1 
ATOM   3055 O  OG1 . THR A 1 395 ? 156.906 111.165 129.873 1.00 70.93  ? 395 THR A OG1 1 
ATOM   3056 C  CG2 . THR A 1 395 ? 157.812 111.922 127.804 1.00 67.84  ? 395 THR A CG2 1 
ATOM   3057 N  N   . PHE A 1 396 ? 160.896 110.217 128.055 1.00 78.15  ? 396 PHE A N   1 
ATOM   3058 C  CA  . PHE A 1 396 ? 161.946 110.215 127.044 1.00 78.30  ? 396 PHE A CA  1 
ATOM   3059 C  C   . PHE A 1 396 ? 162.238 108.802 126.558 1.00 81.03  ? 396 PHE A C   1 
ATOM   3060 O  O   . PHE A 1 396 ? 162.479 108.586 125.365 1.00 85.12  ? 396 PHE A O   1 
ATOM   3061 C  CB  . PHE A 1 396 ? 163.210 110.870 127.597 1.00 77.52  ? 396 PHE A CB  1 
ATOM   3062 C  CG  . PHE A 1 396 ? 164.430 110.629 126.759 1.00 82.79  ? 396 PHE A CG  1 
ATOM   3063 C  CD1 . PHE A 1 396 ? 164.513 111.135 125.474 1.00 84.07  ? 396 PHE A CD1 1 
ATOM   3064 C  CD2 . PHE A 1 396 ? 165.491 109.893 127.254 1.00 82.67  ? 396 PHE A CD2 1 
ATOM   3065 C  CE1 . PHE A 1 396 ? 165.635 110.912 124.699 1.00 83.03  ? 396 PHE A CE1 1 
ATOM   3066 C  CE2 . PHE A 1 396 ? 166.615 109.668 126.485 1.00 82.06  ? 396 PHE A CE2 1 
ATOM   3067 C  CZ  . PHE A 1 396 ? 166.687 110.178 125.206 1.00 81.35  ? 396 PHE A CZ  1 
ATOM   3068 N  N   . LEU A 1 397 ? 162.227 107.824 127.465 1.00 77.87  ? 397 LEU A N   1 
ATOM   3069 C  CA  . LEU A 1 397 ? 162.384 106.438 127.040 1.00 77.03  ? 397 LEU A CA  1 
ATOM   3070 C  C   . LEU A 1 397 ? 161.171 105.951 126.260 1.00 77.56  ? 397 LEU A C   1 
ATOM   3071 O  O   . LEU A 1 397 ? 161.300 105.062 125.413 1.00 82.30  ? 397 LEU A O   1 
ATOM   3072 C  CB  . LEU A 1 397 ? 162.632 105.531 128.245 1.00 83.78  ? 397 LEU A CB  1 
ATOM   3073 C  CG  . LEU A 1 397 ? 164.052 105.431 128.820 1.00 87.42  ? 397 LEU A CG  1 
ATOM   3074 C  CD1 . LEU A 1 397 ? 164.160 104.232 129.755 1.00 81.60  ? 397 LEU A CD1 1 
ATOM   3075 C  CD2 . LEU A 1 397 ? 165.107 105.353 127.724 1.00 84.98  ? 397 LEU A CD2 1 
ATOM   3076 N  N   . CYS A 1 398 ? 159.988 106.505 126.537 1.00 81.15  ? 398 CYS A N   1 
ATOM   3077 C  CA  . CYS A 1 398 ? 158.800 106.121 125.779 1.00 83.71  ? 398 CYS A CA  1 
ATOM   3078 C  C   . CYS A 1 398 ? 158.876 106.618 124.341 1.00 82.67  ? 398 CYS A C   1 
ATOM   3079 O  O   . CYS A 1 398 ? 158.498 105.899 123.410 1.00 84.73  ? 398 CYS A O   1 
ATOM   3080 C  CB  . CYS A 1 398 ? 157.539 106.655 126.460 1.00 86.88  ? 398 CYS A CB  1 
ATOM   3081 S  SG  . CYS A 1 398 ? 156.731 105.500 127.592 1.00 89.97  ? 398 CYS A SG  1 
ATOM   3082 N  N   . LEU A 1 399 ? 159.346 107.850 124.141 1.00 85.26  ? 399 LEU A N   1 
ATOM   3083 C  CA  . LEU A 1 399 ? 159.477 108.379 122.789 1.00 85.88  ? 399 LEU A CA  1 
ATOM   3084 C  C   . LEU A 1 399 ? 160.536 107.624 121.999 1.00 87.71  ? 399 LEU A C   1 
ATOM   3085 O  O   . LEU A 1 399 ? 160.334 107.314 120.821 1.00 90.85  ? 399 LEU A O   1 
ATOM   3086 C  CB  . LEU A 1 399 ? 159.810 109.866 122.837 1.00 85.88  ? 399 LEU A CB  1 
ATOM   3087 C  CG  . LEU A 1 399 ? 158.660 110.774 123.256 1.00 85.43  ? 399 LEU A CG  1 
ATOM   3088 C  CD1 . LEU A 1 399 ? 159.116 111.688 124.369 1.00 86.06  ? 399 LEU A CD1 1 
ATOM   3089 C  CD2 . LEU A 1 399 ? 158.166 111.574 122.071 1.00 88.88  ? 399 LEU A CD2 1 
ATOM   3090 N  N   . TYR A 1 400 ? 161.673 107.326 122.628 1.00 96.74  ? 400 TYR A N   1 
ATOM   3091 C  CA  . TYR A 1 400 ? 162.714 106.567 121.946 1.00 97.85  ? 400 TYR A CA  1 
ATOM   3092 C  C   . TYR A 1 400 ? 162.218 105.178 121.567 1.00 97.55  ? 400 TYR A C   1 
ATOM   3093 O  O   . TYR A 1 400 ? 162.491 104.692 120.465 1.00 100.48 ? 400 TYR A O   1 
ATOM   3094 C  CB  . TYR A 1 400 ? 163.957 106.473 122.829 1.00 99.42  ? 400 TYR A CB  1 
ATOM   3095 C  CG  . TYR A 1 400 ? 164.739 105.193 122.655 1.00 100.60 ? 400 TYR A CG  1 
ATOM   3096 C  CD1 . TYR A 1 400 ? 165.638 105.044 121.607 1.00 99.04  ? 400 TYR A CD1 1 
ATOM   3097 C  CD2 . TYR A 1 400 ? 164.582 104.133 123.538 1.00 100.64 ? 400 TYR A CD2 1 
ATOM   3098 C  CE1 . TYR A 1 400 ? 166.355 103.877 121.444 1.00 99.35  ? 400 TYR A CE1 1 
ATOM   3099 C  CE2 . TYR A 1 400 ? 165.293 102.962 123.381 1.00 99.83  ? 400 TYR A CE2 1 
ATOM   3100 C  CZ  . TYR A 1 400 ? 166.178 102.839 122.333 1.00 99.91  ? 400 TYR A CZ  1 
ATOM   3101 O  OH  . TYR A 1 400 ? 166.891 101.672 122.175 1.00 100.68 ? 400 TYR A OH  1 
ATOM   3102 N  N   . GLY A 1 401 ? 161.479 104.527 122.466 1.00 99.15  ? 401 GLY A N   1 
ATOM   3103 C  CA  . GLY A 1 401 ? 160.961 103.201 122.186 1.00 99.45  ? 401 GLY A CA  1 
ATOM   3104 C  C   . GLY A 1 401 ? 159.884 103.172 121.125 1.00 101.49 ? 401 GLY A C   1 
ATOM   3105 O  O   . GLY A 1 401 ? 159.528 102.089 120.649 1.00 103.48 ? 401 GLY A O   1 
ATOM   3106 N  N   . MET A 1 402 ? 159.347 104.332 120.752 1.00 104.31 ? 402 MET A N   1 
ATOM   3107 C  CA  . MET A 1 402 ? 158.373 104.420 119.673 1.00 104.59 ? 402 MET A CA  1 
ATOM   3108 C  C   . MET A 1 402 ? 158.930 105.081 118.421 1.00 105.27 ? 402 MET A C   1 
ATOM   3109 O  O   . MET A 1 402 ? 158.474 104.769 117.317 1.00 106.70 ? 402 MET A O   1 
ATOM   3110 C  CB  . MET A 1 402 ? 157.108 105.148 120.162 1.00 105.08 ? 402 MET A CB  1 
ATOM   3111 C  CG  . MET A 1 402 ? 157.196 106.659 120.424 1.00 108.08 ? 402 MET A CG  1 
ATOM   3112 S  SD  . MET A 1 402 ? 157.492 107.772 119.034 1.00 111.45 ? 402 MET A SD  1 
ATOM   3113 C  CE  . MET A 1 402 ? 155.956 107.582 118.136 1.00 105.53 ? 402 MET A CE  1 
ATOM   3114 N  N   . ILE A 1 403 ? 159.900 105.986 118.565 1.00 110.31 ? 403 ILE A N   1 
ATOM   3115 C  CA  . ILE A 1 403 ? 160.624 106.490 117.402 1.00 112.20 ? 403 ILE A CA  1 
ATOM   3116 C  C   . ILE A 1 403 ? 161.415 105.364 116.747 1.00 113.55 ? 403 ILE A C   1 
ATOM   3117 O  O   . ILE A 1 403 ? 161.407 105.207 115.521 1.00 114.75 ? 403 ILE A O   1 
ATOM   3118 C  CB  . ILE A 1 403 ? 161.536 107.664 117.804 1.00 112.83 ? 403 ILE A CB  1 
ATOM   3119 C  CG1 . ILE A 1 403 ? 160.735 108.966 117.863 1.00 113.07 ? 403 ILE A CG1 1 
ATOM   3120 C  CG2 . ILE A 1 403 ? 162.713 107.789 116.846 1.00 112.01 ? 403 ILE A CG2 1 
ATOM   3121 C  CD1 . ILE A 1 403 ? 161.574 110.191 118.159 1.00 111.94 ? 403 ILE A CD1 1 
ATOM   3122 N  N   . TRP A 1 404 ? 162.104 104.559 117.558 1.00 123.69 ? 404 TRP A N   1 
ATOM   3123 C  CA  . TRP A 1 404 ? 162.802 103.390 117.040 1.00 124.57 ? 404 TRP A CA  1 
ATOM   3124 C  C   . TRP A 1 404 ? 161.834 102.315 116.562 1.00 124.30 ? 404 TRP A C   1 
ATOM   3125 O  O   . TRP A 1 404 ? 162.216 101.478 115.737 1.00 124.09 ? 404 TRP A O   1 
ATOM   3126 C  CB  . TRP A 1 404 ? 163.740 102.832 118.116 1.00 124.30 ? 404 TRP A CB  1 
ATOM   3127 C  CG  . TRP A 1 404 ? 164.039 101.364 118.002 1.00 126.33 ? 404 TRP A CG  1 
ATOM   3128 C  CD1 . TRP A 1 404 ? 165.150 100.796 117.450 1.00 126.18 ? 404 TRP A CD1 1 
ATOM   3129 C  CD2 . TRP A 1 404 ? 163.219 100.278 118.458 1.00 126.51 ? 404 TRP A CD2 1 
ATOM   3130 N  NE1 . TRP A 1 404 ? 165.073 99.427  117.531 1.00 127.68 ? 404 TRP A NE1 1 
ATOM   3131 C  CE2 . TRP A 1 404 ? 163.896 99.083  118.143 1.00 127.80 ? 404 TRP A CE2 1 
ATOM   3132 C  CE3 . TRP A 1 404 ? 161.977 100.201 119.095 1.00 123.71 ? 404 TRP A CE3 1 
ATOM   3133 C  CZ2 . TRP A 1 404 ? 163.374 97.828  118.446 1.00 126.01 ? 404 TRP A CZ2 1 
ATOM   3134 C  CZ3 . TRP A 1 404 ? 161.460 98.955  119.393 1.00 124.51 ? 404 TRP A CZ3 1 
ATOM   3135 C  CH2 . TRP A 1 404 ? 162.158 97.785  119.070 1.00 125.06 ? 404 TRP A CH2 1 
ATOM   3136 N  N   . TYR A 1 405 ? 160.593 102.324 117.057 1.00 124.13 ? 405 TYR A N   1 
ATOM   3137 C  CA  . TYR A 1 405 ? 159.623 101.306 116.666 1.00 124.29 ? 405 TYR A CA  1 
ATOM   3138 C  C   . TYR A 1 405 ? 159.339 101.356 115.171 1.00 125.81 ? 405 TYR A C   1 
ATOM   3139 O  O   . TYR A 1 405 ? 159.179 100.312 114.527 1.00 125.36 ? 405 TYR A O   1 
ATOM   3140 C  CB  . TYR A 1 405 ? 158.329 101.481 117.461 1.00 124.83 ? 405 TYR A CB  1 
ATOM   3141 C  CG  . TYR A 1 405 ? 157.133 100.781 116.854 1.00 127.14 ? 405 TYR A CG  1 
ATOM   3142 C  CD1 . TYR A 1 405 ? 157.015 99.399  116.897 1.00 127.31 ? 405 TYR A CD1 1 
ATOM   3143 C  CD2 . TYR A 1 405 ? 156.124 101.505 116.232 1.00 126.36 ? 405 TYR A CD2 1 
ATOM   3144 C  CE1 . TYR A 1 405 ? 155.922 98.756  116.341 1.00 125.77 ? 405 TYR A CE1 1 
ATOM   3145 C  CE2 . TYR A 1 405 ? 155.029 100.871 115.674 1.00 125.42 ? 405 TYR A CE2 1 
ATOM   3146 C  CZ  . TYR A 1 405 ? 154.933 99.498  115.731 1.00 125.49 ? 405 TYR A CZ  1 
ATOM   3147 O  OH  . TYR A 1 405 ? 153.845 98.866  115.177 1.00 124.71 ? 405 TYR A OH  1 
ATOM   3148 N  N   . ALA A 1 406 ? 159.262 102.561 114.603 1.00 129.00 ? 406 ALA A N   1 
ATOM   3149 C  CA  . ALA A 1 406 ? 159.047 102.688 113.165 1.00 129.30 ? 406 ALA A CA  1 
ATOM   3150 C  C   . ALA A 1 406 ? 160.203 102.081 112.382 1.00 128.90 ? 406 ALA A C   1 
ATOM   3151 O  O   . ALA A 1 406 ? 159.992 101.426 111.354 1.00 127.64 ? 406 ALA A O   1 
ATOM   3152 C  CB  . ALA A 1 406 ? 158.855 104.157 112.789 1.00 129.20 ? 406 ALA A CB  1 
ATOM   3153 N  N   . GLU A 1 407 ? 161.436 102.293 112.851 1.00 133.88 ? 407 GLU A N   1 
ATOM   3154 C  CA  . GLU A 1 407 ? 162.598 101.731 112.171 1.00 133.56 ? 407 GLU A CA  1 
ATOM   3155 C  C   . GLU A 1 407 ? 162.571 100.208 112.191 1.00 134.44 ? 407 GLU A C   1 
ATOM   3156 O  O   . GLU A 1 407 ? 162.883 99.561  111.184 1.00 134.54 ? 407 GLU A O   1 
ATOM   3157 C  CB  . GLU A 1 407 ? 163.881 102.258 112.812 1.00 133.98 ? 407 GLU A CB  1 
ATOM   3158 C  CG  . GLU A 1 407 ? 163.951 103.777 112.882 1.00 134.79 ? 407 GLU A CG  1 
ATOM   3159 C  CD  . GLU A 1 407 ? 165.087 104.271 113.753 1.00 134.37 ? 407 GLU A CD  1 
ATOM   3160 O  OE1 . GLU A 1 407 ? 165.860 103.431 114.260 1.00 135.13 ? 407 GLU A OE1 1 
ATOM   3161 O  OE2 . GLU A 1 407 ? 165.207 105.501 113.931 1.00 133.12 ? 407 GLU A OE2 1 
ATOM   3162 N  N   . HIS A 1 408 ? 162.202 99.617  113.322 1.00 136.63 ? 408 HIS A N   1 
ATOM   3163 C  CA  . HIS A 1 408 ? 162.095 98.166  113.425 1.00 137.18 ? 408 HIS A CA  1 
ATOM   3164 C  C   . HIS A 1 408 ? 160.642 97.733  113.591 1.00 135.74 ? 408 HIS A C   1 
ATOM   3165 O  O   . HIS A 1 408 ? 159.778 98.110  112.799 1.00 135.50 ? 408 HIS A O   1 
ATOM   3166 C  CB  . HIS A 1 408 ? 162.936 97.644  114.590 1.00 135.59 ? 408 HIS A CB  1 
ATOM   3167 C  CG  . HIS A 1 408 ? 164.401 97.564  114.290 1.00 135.89 ? 408 HIS A CG  1 
ATOM   3168 N  ND1 . HIS A 1 408 ? 165.150 98.666  113.937 1.00 135.76 ? 408 HIS A ND1 1 
ATOM   3169 C  CD2 . HIS A 1 408 ? 165.255 96.513  114.290 1.00 135.49 ? 408 HIS A CD2 1 
ATOM   3170 C  CE1 . HIS A 1 408 ? 166.402 98.297  113.733 1.00 135.89 ? 408 HIS A CE1 1 
ATOM   3171 N  NE2 . HIS A 1 408 ? 166.492 96.996  113.940 1.00 135.63 ? 408 HIS A NE2 1 
ATOM   3172 N  N   . ASP B 1 14  ? 114.472 122.187 112.302 1.00 83.94  ? 14  ASP B N   1 
ATOM   3173 C  CA  . ASP B 1 14  ? 115.053 122.037 113.630 1.00 85.92  ? 14  ASP B CA  1 
ATOM   3174 C  C   . ASP B 1 14  ? 116.420 122.709 113.692 1.00 86.60  ? 14  ASP B C   1 
ATOM   3175 O  O   . ASP B 1 14  ? 116.913 123.037 114.770 1.00 82.95  ? 14  ASP B O   1 
ATOM   3176 C  CB  . ASP B 1 14  ? 115.167 120.560 114.008 1.00 86.98  ? 14  ASP B CB  1 
ATOM   3177 C  CG  . ASP B 1 14  ? 115.083 120.332 115.504 1.00 87.12  ? 14  ASP B CG  1 
ATOM   3178 O  OD1 . ASP B 1 14  ? 115.893 120.925 116.246 1.00 85.33  ? 14  ASP B OD1 1 
ATOM   3179 O  OD2 . ASP B 1 14  ? 114.207 119.556 115.940 1.00 87.50  ? 14  ASP B OD2 1 
ATOM   3180 N  N   . VAL B 1 15  ? 117.033 122.905 112.523 1.00 89.84  ? 15  VAL B N   1 
ATOM   3181 C  CA  . VAL B 1 15  ? 118.280 123.662 112.463 1.00 88.77  ? 15  VAL B CA  1 
ATOM   3182 C  C   . VAL B 1 15  ? 118.051 125.084 112.953 1.00 85.43  ? 15  VAL B C   1 
ATOM   3183 O  O   . VAL B 1 15  ? 118.909 125.675 113.618 1.00 82.62  ? 15  VAL B O   1 
ATOM   3184 C  CB  . VAL B 1 15  ? 118.855 123.643 111.035 1.00 86.17  ? 15  VAL B CB  1 
ATOM   3185 C  CG1 . VAL B 1 15  ? 120.298 124.120 111.043 1.00 85.44  ? 15  VAL B CG1 1 
ATOM   3186 C  CG2 . VAL B 1 15  ? 118.749 122.251 110.437 1.00 85.56  ? 15  VAL B CG2 1 
ATOM   3187 N  N   . ASN B 1 16  ? 116.894 125.657 112.622 1.00 81.02  ? 16  ASN B N   1 
ATOM   3188 C  CA  . ASN B 1 16  ? 116.523 126.961 113.151 1.00 79.22  ? 16  ASN B CA  1 
ATOM   3189 C  C   . ASN B 1 16  ? 116.044 126.873 114.593 1.00 81.82  ? 16  ASN B C   1 
ATOM   3190 O  O   . ASN B 1 16  ? 116.231 127.820 115.362 1.00 83.14  ? 16  ASN B O   1 
ATOM   3191 C  CB  . ASN B 1 16  ? 115.435 127.587 112.281 1.00 81.00  ? 16  ASN B CB  1 
ATOM   3192 C  CG  . ASN B 1 16  ? 115.715 127.434 110.803 1.00 85.56  ? 16  ASN B CG  1 
ATOM   3193 O  OD1 . ASN B 1 16  ? 116.862 127.261 110.392 1.00 86.21  ? 16  ASN B OD1 1 
ATOM   3194 N  ND2 . ASN B 1 16  ? 114.665 127.493 109.992 1.00 83.29  ? 16  ASN B ND2 1 
ATOM   3195 N  N   . TYR B 1 17  ? 115.428 125.752 114.976 1.00 79.28  ? 17  TYR B N   1 
ATOM   3196 C  CA  . TYR B 1 17  ? 114.856 125.639 116.314 1.00 77.86  ? 17  TYR B CA  1 
ATOM   3197 C  C   . TYR B 1 17  ? 115.935 125.572 117.387 1.00 78.14  ? 17  TYR B C   1 
ATOM   3198 O  O   . TYR B 1 17  ? 115.689 125.955 118.536 1.00 76.07  ? 17  TYR B O   1 
ATOM   3199 C  CB  . TYR B 1 17  ? 113.948 124.411 116.392 1.00 76.78  ? 17  TYR B CB  1 
ATOM   3200 C  CG  . TYR B 1 17  ? 112.591 124.598 115.746 1.00 79.33  ? 17  TYR B CG  1 
ATOM   3201 C  CD1 . TYR B 1 17  ? 112.397 125.545 114.750 1.00 79.81  ? 17  TYR B CD1 1 
ATOM   3202 C  CD2 . TYR B 1 17  ? 111.510 123.814 116.118 1.00 79.40  ? 17  TYR B CD2 1 
ATOM   3203 C  CE1 . TYR B 1 17  ? 111.163 125.714 114.153 1.00 77.14  ? 17  TYR B CE1 1 
ATOM   3204 C  CE2 . TYR B 1 17  ? 110.271 123.977 115.525 1.00 79.30  ? 17  TYR B CE2 1 
ATOM   3205 C  CZ  . TYR B 1 17  ? 110.104 124.929 114.544 1.00 77.66  ? 17  TYR B CZ  1 
ATOM   3206 O  OH  . TYR B 1 17  ? 108.876 125.097 113.950 1.00 77.27  ? 17  TYR B OH  1 
ATOM   3207 N  N   . LYS B 1 18  ? 117.123 125.076 117.042 1.00 70.09  ? 18  LYS B N   1 
ATOM   3208 C  CA  . LYS B 1 18  ? 118.248 125.069 117.966 1.00 64.80  ? 18  LYS B CA  1 
ATOM   3209 C  C   . LYS B 1 18  ? 119.164 126.267 117.776 1.00 59.86  ? 18  LYS B C   1 
ATOM   3210 O  O   . LYS B 1 18  ? 119.891 126.633 118.704 1.00 61.70  ? 18  LYS B O   1 
ATOM   3211 C  CB  . LYS B 1 18  ? 119.057 123.781 117.805 1.00 65.23  ? 18  LYS B CB  1 
ATOM   3212 C  CG  . LYS B 1 18  ? 119.653 123.251 119.096 1.00 65.88  ? 18  LYS B CG  1 
ATOM   3213 C  CD  . LYS B 1 18  ? 120.063 121.796 118.942 1.00 67.06  ? 18  LYS B CD  1 
ATOM   3214 C  CE  . LYS B 1 18  ? 120.190 121.108 120.288 1.00 63.45  ? 18  LYS B CE  1 
ATOM   3215 N  NZ  . LYS B 1 18  ? 121.326 121.642 121.082 1.00 61.47  ? 18  LYS B NZ  1 
ATOM   3216 N  N   . MET B 1 19  ? 119.160 126.871 116.587 1.00 64.97  ? 19  MET B N   1 
ATOM   3217 C  CA  . MET B 1 19  ? 119.907 128.105 116.374 1.00 66.66  ? 19  MET B CA  1 
ATOM   3218 C  C   . MET B 1 19  ? 119.177 129.304 116.962 1.00 63.49  ? 19  MET B C   1 
ATOM   3219 O  O   . MET B 1 19  ? 119.814 130.234 117.466 1.00 69.27  ? 19  MET B O   1 
ATOM   3220 C  CB  . MET B 1 19  ? 120.164 128.318 114.882 1.00 72.12  ? 19  MET B CB  1 
ATOM   3221 C  CG  . MET B 1 19  ? 120.619 129.723 114.524 1.00 72.45  ? 19  MET B CG  1 
ATOM   3222 S  SD  . MET B 1 19  ? 120.148 130.221 112.858 1.00 83.05  ? 19  MET B SD  1 
ATOM   3223 C  CE  . MET B 1 19  ? 120.737 131.911 112.835 1.00 70.15  ? 19  MET B CE  1 
ATOM   3224 N  N   . HIS B 1 20  ? 117.844 129.303 116.905 1.00 54.18  ? 20  HIS B N   1 
ATOM   3225 C  CA  . HIS B 1 20  ? 117.079 130.404 117.476 1.00 53.99  ? 20  HIS B CA  1 
ATOM   3226 C  C   . HIS B 1 20  ? 117.162 130.440 118.992 1.00 58.41  ? 20  HIS B C   1 
ATOM   3227 O  O   . HIS B 1 20  ? 116.885 131.484 119.588 1.00 58.27  ? 20  HIS B O   1 
ATOM   3228 C  CB  . HIS B 1 20  ? 115.618 130.321 117.039 1.00 57.45  ? 20  HIS B CB  1 
ATOM   3229 C  CG  . HIS B 1 20  ? 115.257 131.297 115.966 1.00 62.47  ? 20  HIS B CG  1 
ATOM   3230 N  ND1 . HIS B 1 20  ? 114.996 132.624 116.225 1.00 61.45  ? 20  HIS B ND1 1 
ATOM   3231 C  CD2 . HIS B 1 20  ? 115.131 131.144 114.627 1.00 62.75  ? 20  HIS B CD2 1 
ATOM   3232 C  CE1 . HIS B 1 20  ? 114.716 133.245 115.093 1.00 62.50  ? 20  HIS B CE1 1 
ATOM   3233 N  NE2 . HIS B 1 20  ? 114.793 132.369 114.108 1.00 61.99  ? 20  HIS B NE2 1 
ATOM   3234 N  N   . PHE B 1 21  ? 117.524 129.330 119.631 1.00 50.87  ? 21  PHE B N   1 
ATOM   3235 C  CA  . PHE B 1 21  ? 117.744 129.355 121.070 1.00 34.48  ? 21  PHE B CA  1 
ATOM   3236 C  C   . PHE B 1 21  ? 119.063 130.028 121.420 1.00 40.75  ? 21  PHE B C   1 
ATOM   3237 O  O   . PHE B 1 21  ? 119.162 130.703 122.448 1.00 54.15  ? 21  PHE B O   1 
ATOM   3238 C  CB  . PHE B 1 21  ? 117.702 127.943 121.640 1.00 31.55  ? 21  PHE B CB  1 
ATOM   3239 C  CG  . PHE B 1 21  ? 117.938 127.887 123.114 1.00 37.00  ? 21  PHE B CG  1 
ATOM   3240 C  CD1 . PHE B 1 21  ? 117.075 128.520 123.987 1.00 42.38  ? 21  PHE B CD1 1 
ATOM   3241 C  CD2 . PHE B 1 21  ? 119.022 127.209 123.630 1.00 45.15  ? 21  PHE B CD2 1 
ATOM   3242 C  CE1 . PHE B 1 21  ? 117.286 128.475 125.341 1.00 35.28  ? 21  PHE B CE1 1 
ATOM   3243 C  CE2 . PHE B 1 21  ? 119.237 127.163 124.984 1.00 48.81  ? 21  PHE B CE2 1 
ATOM   3244 C  CZ  . PHE B 1 21  ? 118.366 127.796 125.839 1.00 40.69  ? 21  PHE B CZ  1 
ATOM   3245 N  N   . ARG B 1 22  ? 120.085 129.860 120.587 1.00 46.44  ? 22  ARG B N   1 
ATOM   3246 C  CA  . ARG B 1 22  ? 121.357 130.528 120.823 1.00 47.40  ? 22  ARG B CA  1 
ATOM   3247 C  C   . ARG B 1 22  ? 121.324 132.015 120.507 1.00 51.64  ? 22  ARG B C   1 
ATOM   3248 O  O   . ARG B 1 22  ? 122.289 132.713 120.820 1.00 58.21  ? 22  ARG B O   1 
ATOM   3249 C  CB  . ARG B 1 22  ? 122.473 129.860 120.025 1.00 48.27  ? 22  ARG B CB  1 
ATOM   3250 C  CG  . ARG B 1 22  ? 122.633 128.383 120.300 1.00 52.55  ? 22  ARG B CG  1 
ATOM   3251 C  CD  . ARG B 1 22  ? 124.022 127.931 119.894 1.00 54.86  ? 22  ARG B CD  1 
ATOM   3252 N  NE  . ARG B 1 22  ? 125.030 128.922 120.256 1.00 63.39  ? 22  ARG B NE  1 
ATOM   3253 C  CZ  . ARG B 1 22  ? 126.057 128.699 121.066 1.00 64.39  ? 22  ARG B CZ  1 
ATOM   3254 N  NH1 . ARG B 1 22  ? 126.232 127.530 121.657 1.00 58.57  ? 22  ARG B NH1 1 
ATOM   3255 N  NH2 . ARG B 1 22  ? 126.927 129.679 121.292 1.00 59.74  ? 22  ARG B NH2 1 
ATOM   3256 N  N   . MET B 1 23  ? 120.260 132.525 119.896 1.00 45.57  ? 23  MET B N   1 
ATOM   3257 C  CA  . MET B 1 23  ? 120.065 133.965 119.847 1.00 42.04  ? 23  MET B CA  1 
ATOM   3258 C  C   . MET B 1 23  ? 119.376 134.492 121.092 1.00 47.64  ? 23  MET B C   1 
ATOM   3259 O  O   . MET B 1 23  ? 119.460 135.691 121.371 1.00 52.91  ? 23  MET B O   1 
ATOM   3260 C  CB  . MET B 1 23  ? 119.251 134.354 118.610 1.00 45.32  ? 23  MET B CB  1 
ATOM   3261 C  CG  . MET B 1 23  ? 119.900 133.967 117.297 1.00 53.50  ? 23  MET B CG  1 
ATOM   3262 S  SD  . MET B 1 23  ? 118.747 133.975 115.914 1.00 67.42  ? 23  MET B SD  1 
ATOM   3263 C  CE  . MET B 1 23  ? 117.432 134.993 116.574 1.00 50.48  ? 23  MET B CE  1 
ATOM   3264 N  N   . ILE B 1 24  ? 118.702 133.618 121.835 1.00 37.81  ? 24  ILE B N   1 
ATOM   3265 C  CA  . ILE B 1 24  ? 118.118 133.985 123.117 1.00 27.56  ? 24  ILE B CA  1 
ATOM   3266 C  C   . ILE B 1 24  ? 119.113 133.746 124.239 1.00 33.86  ? 24  ILE B C   1 
ATOM   3267 O  O   . ILE B 1 24  ? 119.368 134.629 125.062 1.00 50.67  ? 24  ILE B O   1 
ATOM   3268 C  CB  . ILE B 1 24  ? 116.822 133.190 123.352 1.00 33.55  ? 24  ILE B CB  1 
ATOM   3269 C  CG1 . ILE B 1 24  ? 115.630 133.851 122.681 1.00 33.76  ? 24  ILE B CG1 1 
ATOM   3270 C  CG2 . ILE B 1 24  ? 116.541 133.037 124.824 1.00 38.63  ? 24  ILE B CG2 1 
ATOM   3271 C  CD1 . ILE B 1 24  ? 114.350 133.108 122.964 1.00 38.77  ? 24  ILE B CD1 1 
ATOM   3272 N  N   . ASN B 1 25  ? 119.697 132.550 124.282 1.00 22.91  ? 25  ASN B N   1 
ATOM   3273 C  CA  . ASN B 1 25  ? 120.492 132.144 125.432 1.00 25.07  ? 25  ASN B CA  1 
ATOM   3274 C  C   . ASN B 1 25  ? 121.896 132.737 125.386 1.00 34.65  ? 25  ASN B C   1 
ATOM   3275 O  O   . ASN B 1 25  ? 122.319 133.420 126.321 1.00 36.85  ? 25  ASN B O   1 
ATOM   3276 C  CB  . ASN B 1 25  ? 120.552 130.621 125.508 1.00 28.21  ? 25  ASN B CB  1 
ATOM   3277 C  CG  . ASN B 1 25  ? 120.637 130.118 126.923 1.00 38.84  ? 25  ASN B CG  1 
ATOM   3278 O  OD1 . ASN B 1 25  ? 120.270 130.820 127.862 1.00 40.54  ? 25  ASN B OD1 1 
ATOM   3279 N  ND2 . ASN B 1 25  ? 121.130 128.898 127.090 1.00 36.03  ? 25  ASN B ND2 1 
ATOM   3280 N  N   . GLU B 1 26  ? 122.640 132.482 124.314 1.00 38.40  ? 26  GLU B N   1 
ATOM   3281 C  CA  . GLU B 1 26  ? 124.029 132.930 124.209 1.00 36.64  ? 26  GLU B CA  1 
ATOM   3282 C  C   . GLU B 1 26  ? 124.183 133.793 122.965 1.00 40.60  ? 26  GLU B C   1 
ATOM   3283 O  O   . GLU B 1 26  ? 124.639 133.321 121.925 1.00 46.65  ? 26  GLU B O   1 
ATOM   3284 C  CB  . GLU B 1 26  ? 124.965 131.751 124.166 1.00 40.54  ? 26  GLU B CB  1 
ATOM   3285 C  CG  . GLU B 1 26  ? 124.486 130.535 124.919 1.00 47.49  ? 26  GLU B CG  1 
ATOM   3286 C  CD  . GLU B 1 26  ? 125.631 129.732 125.487 1.00 51.05  ? 26  GLU B CD  1 
ATOM   3287 O  OE1 . GLU B 1 26  ? 126.734 130.296 125.627 1.00 46.49  ? 26  GLU B OE1 1 
ATOM   3288 O  OE2 . GLU B 1 26  ? 125.433 128.538 125.791 1.00 56.18  ? 26  GLU B OE2 1 
ATOM   3289 N  N   . GLN B 1 27  ? 123.849 135.073 123.089 1.00 37.84  ? 27  GLN B N   1 
ATOM   3290 C  CA  . GLN B 1 27  ? 123.994 135.985 121.967 1.00 31.84  ? 27  GLN B CA  1 
ATOM   3291 C  C   . GLN B 1 27  ? 125.469 136.244 121.695 1.00 40.96  ? 27  GLN B C   1 
ATOM   3292 O  O   . GLN B 1 27  ? 126.234 136.559 122.610 1.00 44.29  ? 27  GLN B O   1 
ATOM   3293 C  CB  . GLN B 1 27  ? 123.266 137.293 122.251 1.00 34.93  ? 27  GLN B CB  1 
ATOM   3294 C  CG  . GLN B 1 27  ? 123.568 138.394 121.261 1.00 45.35  ? 27  GLN B CG  1 
ATOM   3295 C  CD  . GLN B 1 27  ? 122.875 138.187 119.937 1.00 49.94  ? 27  GLN B CD  1 
ATOM   3296 O  OE1 . GLN B 1 27  ? 121.968 137.366 119.824 1.00 55.99  ? 27  GLN B OE1 1 
ATOM   3297 N  NE2 . GLN B 1 27  ? 123.302 138.925 118.923 1.00 47.73  ? 27  GLN B NE2 1 
ATOM   3298 N  N   . GLN B 1 28  ? 125.868 136.112 120.434 1.00 52.42  ? 28  GLN B N   1 
ATOM   3299 C  CA  . GLN B 1 28  ? 127.266 136.209 120.045 1.00 53.13  ? 28  GLN B CA  1 
ATOM   3300 C  C   . GLN B 1 28  ? 127.622 137.631 119.640 1.00 53.29  ? 28  GLN B C   1 
ATOM   3301 O  O   . GLN B 1 28  ? 126.779 138.392 119.163 1.00 51.70  ? 28  GLN B O   1 
ATOM   3302 C  CB  . GLN B 1 28  ? 127.569 135.254 118.893 1.00 51.12  ? 28  GLN B CB  1 
ATOM   3303 C  CG  . GLN B 1 28  ? 127.301 133.801 119.217 1.00 55.23  ? 28  GLN B CG  1 
ATOM   3304 C  CD  . GLN B 1 28  ? 128.487 133.129 119.868 1.00 61.85  ? 28  GLN B CD  1 
ATOM   3305 O  OE1 . GLN B 1 28  ? 129.525 132.936 119.238 1.00 62.76  ? 28  GLN B OE1 1 
ATOM   3306 N  NE2 . GLN B 1 28  ? 128.342 132.771 121.138 1.00 56.12  ? 28  GLN B NE2 1 
ATOM   3307 N  N   . VAL B 1 29  ? 128.887 137.980 119.835 1.00 52.47  ? 29  VAL B N   1 
ATOM   3308 C  CA  . VAL B 1 29  ? 129.371 139.313 119.500 1.00 50.95  ? 29  VAL B CA  1 
ATOM   3309 C  C   . VAL B 1 29  ? 129.578 139.405 117.996 1.00 54.77  ? 29  VAL B C   1 
ATOM   3310 O  O   . VAL B 1 29  ? 130.222 138.542 117.389 1.00 54.73  ? 29  VAL B O   1 
ATOM   3311 C  CB  . VAL B 1 29  ? 130.668 139.629 120.257 1.00 48.37  ? 29  VAL B CB  1 
ATOM   3312 C  CG1 . VAL B 1 29  ? 130.879 141.124 120.322 1.00 47.09  ? 29  VAL B CG1 1 
ATOM   3313 C  CG2 . VAL B 1 29  ? 130.623 139.031 121.643 1.00 47.59  ? 29  VAL B CG2 1 
ATOM   3314 N  N   . GLU B 1 30  ? 129.036 140.456 117.393 1.00 61.70  ? 30  GLU B N   1 
ATOM   3315 C  CA  . GLU B 1 30  ? 129.143 140.686 115.962 1.00 59.82  ? 30  GLU B CA  1 
ATOM   3316 C  C   . GLU B 1 30  ? 130.177 141.768 115.690 1.00 62.13  ? 30  GLU B C   1 
ATOM   3317 O  O   . GLU B 1 30  ? 130.264 142.753 116.427 1.00 64.92  ? 30  GLU B O   1 
ATOM   3318 C  CB  . GLU B 1 30  ? 127.793 141.095 115.369 1.00 62.99  ? 30  GLU B CB  1 
ATOM   3319 C  CG  . GLU B 1 30  ? 126.933 139.924 114.920 1.00 64.37  ? 30  GLU B CG  1 
ATOM   3320 C  CD  . GLU B 1 30  ? 125.929 139.495 115.971 1.00 67.64  ? 30  GLU B CD  1 
ATOM   3321 O  OE1 . GLU B 1 30  ? 125.772 140.219 116.976 1.00 65.65  ? 30  GLU B OE1 1 
ATOM   3322 O  OE2 . GLU B 1 30  ? 125.297 138.433 115.792 1.00 65.03  ? 30  GLU B OE2 1 
ATOM   3323 N  N   . ASP B 1 31  ? 130.961 141.570 114.632 1.00 66.18  ? 31  ASP B N   1 
ATOM   3324 C  CA  . ASP B 1 31  ? 131.932 142.555 114.159 1.00 66.05  ? 31  ASP B CA  1 
ATOM   3325 C  C   . ASP B 1 31  ? 132.940 142.911 115.253 1.00 67.70  ? 31  ASP B C   1 
ATOM   3326 O  O   . ASP B 1 31  ? 133.015 144.045 115.726 1.00 67.46  ? 31  ASP B O   1 
ATOM   3327 C  CB  . ASP B 1 31  ? 131.226 143.808 113.629 1.00 64.79  ? 31  ASP B CB  1 
ATOM   3328 C  CG  . ASP B 1 31  ? 130.432 143.540 112.364 1.00 69.86  ? 31  ASP B CG  1 
ATOM   3329 O  OD1 . ASP B 1 31  ? 130.604 142.457 111.766 1.00 68.65  ? 31  ASP B OD1 1 
ATOM   3330 O  OD2 . ASP B 1 31  ? 129.634 144.413 111.967 1.00 70.64  ? 31  ASP B OD2 1 
ATOM   3331 N  N   . ILE B 1 32  ? 133.716 141.910 115.650 1.00 65.75  ? 32  ILE B N   1 
ATOM   3332 C  CA  . ILE B 1 32  ? 134.797 142.109 116.607 1.00 62.09  ? 32  ILE B CA  1 
ATOM   3333 C  C   . ILE B 1 32  ? 136.006 142.672 115.876 1.00 64.95  ? 32  ILE B C   1 
ATOM   3334 O  O   . ILE B 1 32  ? 136.455 142.108 114.872 1.00 70.85  ? 32  ILE B O   1 
ATOM   3335 C  CB  . ILE B 1 32  ? 135.149 140.790 117.310 1.00 58.94  ? 32  ILE B CB  1 
ATOM   3336 C  CG1 . ILE B 1 32  ? 133.933 140.228 118.040 1.00 62.69  ? 32  ILE B CG1 1 
ATOM   3337 C  CG2 . ILE B 1 32  ? 136.296 140.993 118.275 1.00 60.32  ? 32  ILE B CG2 1 
ATOM   3338 C  CD1 . ILE B 1 32  ? 134.105 138.795 118.465 1.00 64.21  ? 32  ILE B CD1 1 
ATOM   3339 N  N   . THR B 1 33  ? 136.535 143.787 116.372 1.00 60.31  ? 33  THR B N   1 
ATOM   3340 C  CA  . THR B 1 33  ? 137.750 144.380 115.828 1.00 63.23  ? 33  THR B CA  1 
ATOM   3341 C  C   . THR B 1 33  ? 138.926 144.272 116.784 1.00 64.57  ? 33  THR B C   1 
ATOM   3342 O  O   . THR B 1 33  ? 140.016 143.857 116.380 1.00 68.53  ? 33  THR B O   1 
ATOM   3343 C  CB  . THR B 1 33  ? 137.513 145.849 115.464 1.00 63.27  ? 33  THR B CB  1 
ATOM   3344 O  OG1 . THR B 1 33  ? 137.150 146.582 116.639 1.00 65.62  ? 33  THR B OG1 1 
ATOM   3345 C  CG2 . THR B 1 33  ? 136.402 145.965 114.441 1.00 63.75  ? 33  THR B CG2 1 
ATOM   3346 N  N   . ILE B 1 34  ? 138.733 144.639 118.047 1.00 57.27  ? 34  ILE B N   1 
ATOM   3347 C  CA  . ILE B 1 34  ? 139.731 144.419 119.086 1.00 53.74  ? 34  ILE B CA  1 
ATOM   3348 C  C   . ILE B 1 34  ? 139.482 143.016 119.629 1.00 61.29  ? 34  ILE B C   1 
ATOM   3349 O  O   . ILE B 1 34  ? 138.536 142.785 120.381 1.00 65.92  ? 34  ILE B O   1 
ATOM   3350 C  CB  . ILE B 1 34  ? 139.658 145.482 120.181 1.00 54.23  ? 34  ILE B CB  1 
ATOM   3351 C  CG1 . ILE B 1 34  ? 140.164 146.820 119.650 1.00 58.78  ? 34  ILE B CG1 1 
ATOM   3352 C  CG2 . ILE B 1 34  ? 140.475 145.070 121.381 1.00 55.84  ? 34  ILE B CG2 1 
ATOM   3353 C  CD1 . ILE B 1 34  ? 140.168 147.910 120.683 1.00 61.55  ? 34  ILE B CD1 1 
ATOM   3354 N  N   . ASP B 1 35  ? 140.325 142.070 119.227 1.00 59.99  ? 35  ASP B N   1 
ATOM   3355 C  CA  . ASP B 1 35  ? 140.155 140.672 119.593 1.00 53.19  ? 35  ASP B CA  1 
ATOM   3356 C  C   . ASP B 1 35  ? 140.839 140.315 120.901 1.00 55.25  ? 35  ASP B C   1 
ATOM   3357 O  O   . ASP B 1 35  ? 140.746 139.164 121.335 1.00 57.77  ? 35  ASP B O   1 
ATOM   3358 C  CB  . ASP B 1 35  ? 140.678 139.767 118.475 1.00 56.58  ? 35  ASP B CB  1 
ATOM   3359 C  CG  . ASP B 1 35  ? 139.707 138.654 118.122 1.00 65.27  ? 35  ASP B CG  1 
ATOM   3360 O  OD1 . ASP B 1 35  ? 139.260 137.937 119.040 1.00 60.96  ? 35  ASP B OD1 1 
ATOM   3361 O  OD2 . ASP B 1 35  ? 139.389 138.496 116.924 1.00 68.19  ? 35  ASP B OD2 1 
ATOM   3362 N  N   . PHE B 1 36  ? 141.530 141.262 121.536 1.00 55.73  ? 36  PHE B N   1 
ATOM   3363 C  CA  . PHE B 1 36  ? 142.084 140.994 122.858 1.00 55.76  ? 36  PHE B CA  1 
ATOM   3364 C  C   . PHE B 1 36  ? 140.982 140.842 123.898 1.00 57.52  ? 36  PHE B C   1 
ATOM   3365 O  O   . PHE B 1 36  ? 141.157 140.123 124.887 1.00 56.99  ? 36  PHE B O   1 
ATOM   3366 C  CB  . PHE B 1 36  ? 143.052 142.106 123.265 1.00 49.34  ? 36  PHE B CB  1 
ATOM   3367 C  CG  . PHE B 1 36  ? 143.182 142.280 124.749 1.00 51.97  ? 36  PHE B CG  1 
ATOM   3368 C  CD1 . PHE B 1 36  ? 143.993 141.437 125.485 1.00 58.14  ? 36  PHE B CD1 1 
ATOM   3369 C  CD2 . PHE B 1 36  ? 142.495 143.281 125.408 1.00 55.99  ? 36  PHE B CD2 1 
ATOM   3370 C  CE1 . PHE B 1 36  ? 144.113 141.587 126.853 1.00 60.02  ? 36  PHE B CE1 1 
ATOM   3371 C  CE2 . PHE B 1 36  ? 142.610 143.434 126.774 1.00 56.58  ? 36  PHE B CE2 1 
ATOM   3372 C  CZ  . PHE B 1 36  ? 143.421 142.587 127.497 1.00 56.43  ? 36  PHE B CZ  1 
ATOM   3373 N  N   . PHE B 1 37  ? 139.846 141.499 123.688 1.00 54.16  ? 37  PHE B N   1 
ATOM   3374 C  CA  . PHE B 1 37  ? 138.745 141.489 124.639 1.00 48.18  ? 37  PHE B CA  1 
ATOM   3375 C  C   . PHE B 1 37  ? 137.833 140.283 124.485 1.00 46.98  ? 37  PHE B C   1 
ATOM   3376 O  O   . PHE B 1 37  ? 136.891 140.144 125.269 1.00 51.75  ? 37  PHE B O   1 
ATOM   3377 C  CB  . PHE B 1 37  ? 137.916 142.765 124.490 1.00 49.40  ? 37  PHE B CB  1 
ATOM   3378 C  CG  . PHE B 1 37  ? 138.471 143.941 125.232 1.00 50.69  ? 37  PHE B CG  1 
ATOM   3379 C  CD1 . PHE B 1 37  ? 138.359 144.025 126.603 1.00 47.90  ? 37  PHE B CD1 1 
ATOM   3380 C  CD2 . PHE B 1 37  ? 139.102 144.966 124.556 1.00 48.85  ? 37  PHE B CD2 1 
ATOM   3381 C  CE1 . PHE B 1 37  ? 138.867 145.104 127.285 1.00 47.80  ? 37  PHE B CE1 1 
ATOM   3382 C  CE2 . PHE B 1 37  ? 139.610 146.047 125.234 1.00 49.06  ? 37  PHE B CE2 1 
ATOM   3383 C  CZ  . PHE B 1 37  ? 139.492 146.116 126.600 1.00 48.43  ? 37  PHE B CZ  1 
ATOM   3384 N  N   . TYR B 1 38  ? 138.077 139.415 123.499 1.00 49.99  ? 38  TYR B N   1 
ATOM   3385 C  CA  . TYR B 1 38  ? 137.166 138.307 123.239 1.00 50.91  ? 38  TYR B CA  1 
ATOM   3386 C  C   . TYR B 1 38  ? 137.896 136.993 122.982 1.00 51.97  ? 38  TYR B C   1 
ATOM   3387 O  O   . TYR B 1 38  ? 137.309 136.077 122.396 1.00 56.36  ? 38  TYR B O   1 
ATOM   3388 C  CB  . TYR B 1 38  ? 136.256 138.626 122.050 1.00 47.41  ? 38  TYR B CB  1 
ATOM   3389 C  CG  . TYR B 1 38  ? 135.309 139.777 122.294 1.00 47.38  ? 38  TYR B CG  1 
ATOM   3390 C  CD1 . TYR B 1 38  ? 134.180 139.615 123.077 1.00 51.85  ? 38  TYR B CD1 1 
ATOM   3391 C  CD2 . TYR B 1 38  ? 135.547 141.027 121.743 1.00 49.47  ? 38  TYR B CD2 1 
ATOM   3392 C  CE1 . TYR B 1 38  ? 133.316 140.663 123.305 1.00 56.03  ? 38  TYR B CE1 1 
ATOM   3393 C  CE2 . TYR B 1 38  ? 134.687 142.080 121.967 1.00 49.71  ? 38  TYR B CE2 1 
ATOM   3394 C  CZ  . TYR B 1 38  ? 133.572 141.892 122.747 1.00 51.96  ? 38  TYR B CZ  1 
ATOM   3395 O  OH  . TYR B 1 38  ? 132.705 142.932 122.978 1.00 47.44  ? 38  TYR B OH  1 
ATOM   3396 N  N   . ARG B 1 39  ? 139.155 136.873 123.397 1.00 49.00  ? 39  ARG B N   1 
ATOM   3397 C  CA  . ARG B 1 39  ? 139.905 135.634 123.256 1.00 46.11  ? 39  ARG B CA  1 
ATOM   3398 C  C   . ARG B 1 39  ? 140.092 135.001 124.623 1.00 53.95  ? 39  ARG B C   1 
ATOM   3399 O  O   . ARG B 1 39  ? 140.693 135.629 125.507 1.00 58.29  ? 39  ARG B O   1 
ATOM   3400 C  CB  . ARG B 1 39  ? 141.257 135.886 122.597 1.00 50.90  ? 39  ARG B CB  1 
ATOM   3401 C  CG  . ARG B 1 39  ? 141.330 135.424 121.156 1.00 53.89  ? 39  ARG B CG  1 
ATOM   3402 C  CD  . ARG B 1 39  ? 142.520 136.033 120.444 1.00 54.67  ? 39  ARG B CD  1 
ATOM   3403 N  NE  . ARG B 1 39  ? 142.321 136.072 119.001 1.00 59.60  ? 39  ARG B NE  1 
ATOM   3404 C  CZ  . ARG B 1 39  ? 143.078 136.761 118.160 1.00 57.80  ? 39  ARG B CZ  1 
ATOM   3405 N  NH1 . ARG B 1 39  ? 144.108 137.475 118.584 1.00 59.29  ? 39  ARG B NH1 1 
ATOM   3406 N  NH2 . ARG B 1 39  ? 142.796 136.734 116.860 1.00 53.43  ? 39  ARG B NH2 1 
ATOM   3407 N  N   . PRO B 1 40  ? 139.606 133.783 124.846 1.00 44.41  ? 40  PRO B N   1 
ATOM   3408 C  CA  . PRO B 1 40  ? 139.690 133.187 126.180 1.00 39.60  ? 40  PRO B CA  1 
ATOM   3409 C  C   . PRO B 1 40  ? 141.125 132.930 126.600 1.00 48.25  ? 40  PRO B C   1 
ATOM   3410 O  O   . PRO B 1 40  ? 142.010 132.707 125.773 1.00 53.57  ? 40  PRO B O   1 
ATOM   3411 C  CB  . PRO B 1 40  ? 138.919 131.875 126.024 1.00 41.04  ? 40  PRO B CB  1 
ATOM   3412 C  CG  . PRO B 1 40  ? 139.049 131.553 124.591 1.00 42.10  ? 40  PRO B CG  1 
ATOM   3413 C  CD  . PRO B 1 40  ? 139.000 132.861 123.876 1.00 42.45  ? 40  PRO B CD  1 
ATOM   3414 N  N   . HIS B 1 41  ? 141.350 132.982 127.909 1.00 43.50  ? 41  HIS B N   1 
ATOM   3415 C  CA  . HIS B 1 41  ? 142.640 132.663 128.510 1.00 39.74  ? 41  HIS B CA  1 
ATOM   3416 C  C   . HIS B 1 41  ? 142.425 131.797 129.745 1.00 39.76  ? 41  HIS B C   1 
ATOM   3417 O  O   . HIS B 1 41  ? 142.926 132.083 130.831 1.00 43.86  ? 41  HIS B O   1 
ATOM   3418 C  CB  . HIS B 1 41  ? 143.420 133.932 128.837 1.00 40.00  ? 41  HIS B CB  1 
ATOM   3419 C  CG  . HIS B 1 41  ? 143.839 134.704 127.627 1.00 41.55  ? 41  HIS B CG  1 
ATOM   3420 N  ND1 . HIS B 1 41  ? 144.511 134.126 126.574 1.00 42.14  ? 41  HIS B ND1 1 
ATOM   3421 C  CD2 . HIS B 1 41  ? 143.677 136.007 127.301 1.00 46.82  ? 41  HIS B CD2 1 
ATOM   3422 C  CE1 . HIS B 1 41  ? 144.747 135.040 125.651 1.00 44.01  ? 41  HIS B CE1 1 
ATOM   3423 N  NE2 . HIS B 1 41  ? 144.252 136.190 126.068 1.00 49.25  ? 41  HIS B NE2 1 
ATOM   3424 N  N   . THR B 1 42  ? 141.647 130.726 129.581 1.00 34.57  ? 42  THR B N   1 
ATOM   3425 C  CA  . THR B 1 42  ? 141.204 129.931 130.721 1.00 32.69  ? 42  THR B CA  1 
ATOM   3426 C  C   . THR B 1 42  ? 142.375 129.349 131.503 1.00 34.48  ? 42  THR B C   1 
ATOM   3427 O  O   . THR B 1 42  ? 142.307 129.238 132.732 1.00 46.43  ? 42  THR B O   1 
ATOM   3428 C  CB  . THR B 1 42  ? 140.276 128.819 130.247 1.00 34.84  ? 42  THR B CB  1 
ATOM   3429 O  OG1 . THR B 1 42  ? 140.950 128.019 129.274 1.00 39.83  ? 42  THR B OG1 1 
ATOM   3430 C  CG2 . THR B 1 42  ? 139.041 129.409 129.619 1.00 34.49  ? 42  THR B CG2 1 
ATOM   3431 N  N   . ILE B 1 43  ? 143.449 128.952 130.820 1.00 35.69  ? 43  ILE B N   1 
ATOM   3432 C  CA  . ILE B 1 43  ? 144.603 128.408 131.531 1.00 31.23  ? 43  ILE B CA  1 
ATOM   3433 C  C   . ILE B 1 43  ? 145.271 129.486 132.377 1.00 36.60  ? 43  ILE B C   1 
ATOM   3434 O  O   . ILE B 1 43  ? 145.775 129.210 133.470 1.00 42.43  ? 43  ILE B O   1 
ATOM   3435 C  CB  . ILE B 1 43  ? 145.588 127.758 130.545 1.00 35.20  ? 43  ILE B CB  1 
ATOM   3436 C  CG1 . ILE B 1 43  ? 144.936 126.560 129.863 1.00 36.66  ? 43  ILE B CG1 1 
ATOM   3437 C  CG2 . ILE B 1 43  ? 146.842 127.317 131.259 1.00 37.12  ? 43  ILE B CG2 1 
ATOM   3438 C  CD1 . ILE B 1 43  ? 145.822 125.877 128.864 1.00 33.66  ? 43  ILE B CD1 1 
ATOM   3439 N  N   . THR B 1 44  ? 145.291 130.729 131.891 1.00 37.69  ? 44  THR B N   1 
ATOM   3440 C  CA  . THR B 1 44  ? 145.721 131.833 132.742 1.00 36.85  ? 44  THR B CA  1 
ATOM   3441 C  C   . THR B 1 44  ? 144.732 132.075 133.872 1.00 40.70  ? 44  THR B C   1 
ATOM   3442 O  O   . THR B 1 44  ? 145.133 132.460 134.974 1.00 46.05  ? 44  THR B O   1 
ATOM   3443 C  CB  . THR B 1 44  ? 145.898 133.106 131.922 1.00 38.98  ? 44  THR B CB  1 
ATOM   3444 O  OG1 . THR B 1 44  ? 146.645 132.811 130.740 1.00 47.79  ? 44  THR B OG1 1 
ATOM   3445 C  CG2 . THR B 1 44  ? 146.645 134.146 132.726 1.00 40.00  ? 44  THR B CG2 1 
ATOM   3446 N  N   . LEU B 1 45  ? 143.440 131.875 133.615 1.00 38.58  ? 45  LEU B N   1 
ATOM   3447 C  CA  . LEU B 1 45  ? 142.463 131.892 134.695 1.00 38.30  ? 45  LEU B CA  1 
ATOM   3448 C  C   . LEU B 1 45  ? 142.637 130.692 135.614 1.00 37.06  ? 45  LEU B C   1 
ATOM   3449 O  O   . LEU B 1 45  ? 142.429 130.806 136.824 1.00 41.50  ? 45  LEU B O   1 
ATOM   3450 C  CB  . LEU B 1 45  ? 141.051 131.925 134.119 1.00 36.79  ? 45  LEU B CB  1 
ATOM   3451 C  CG  . LEU B 1 45  ? 139.954 132.438 135.040 1.00 35.61  ? 45  LEU B CG  1 
ATOM   3452 C  CD1 . LEU B 1 45  ? 140.276 133.840 135.483 1.00 40.59  ? 45  LEU B CD1 1 
ATOM   3453 C  CD2 . LEU B 1 45  ? 138.623 132.395 134.328 1.00 35.98  ? 45  LEU B CD2 1 
ATOM   3454 N  N   . LEU B 1 46  ? 143.009 129.538 135.061 1.00 34.71  ? 46  LEU B N   1 
ATOM   3455 C  CA  . LEU B 1 46  ? 143.313 128.377 135.891 1.00 30.90  ? 46  LEU B CA  1 
ATOM   3456 C  C   . LEU B 1 46  ? 144.521 128.641 136.778 1.00 35.46  ? 46  LEU B C   1 
ATOM   3457 O  O   . LEU B 1 46  ? 144.535 128.256 137.951 1.00 47.12  ? 46  LEU B O   1 
ATOM   3458 C  CB  . LEU B 1 46  ? 143.545 127.157 134.999 1.00 35.06  ? 46  LEU B CB  1 
ATOM   3459 C  CG  . LEU B 1 46  ? 144.111 125.845 135.537 1.00 27.81  ? 46  LEU B CG  1 
ATOM   3460 C  CD1 . LEU B 1 46  ? 143.474 125.470 136.832 1.00 26.61  ? 46  LEU B CD1 1 
ATOM   3461 C  CD2 . LEU B 1 46  ? 143.882 124.753 134.524 1.00 33.77  ? 46  LEU B CD2 1 
ATOM   3462 N  N   . SER B 1 47  ? 145.546 129.292 136.237 1.00 39.86  ? 47  SER B N   1 
ATOM   3463 C  CA  . SER B 1 47  ? 146.729 129.611 137.022 1.00 40.12  ? 47  SER B CA  1 
ATOM   3464 C  C   . SER B 1 47  ? 146.498 130.752 137.999 1.00 40.78  ? 47  SER B C   1 
ATOM   3465 O  O   . SER B 1 47  ? 147.221 130.851 138.992 1.00 44.20  ? 47  SER B O   1 
ATOM   3466 C  CB  . SER B 1 47  ? 147.891 129.961 136.097 1.00 40.11  ? 47  SER B CB  1 
ATOM   3467 O  OG  . SER B 1 47  ? 148.874 130.706 136.789 1.00 44.96  ? 47  SER B OG  1 
ATOM   3468 N  N   . PHE B 1 48  ? 145.525 131.623 137.735 1.00 39.45  ? 48  PHE B N   1 
ATOM   3469 C  CA  . PHE B 1 48  ? 145.257 132.726 138.649 1.00 39.99  ? 48  PHE B CA  1 
ATOM   3470 C  C   . PHE B 1 48  ? 144.535 132.249 139.903 1.00 43.28  ? 48  PHE B C   1 
ATOM   3471 O  O   . PHE B 1 48  ? 144.848 132.700 141.010 1.00 46.76  ? 48  PHE B O   1 
ATOM   3472 C  CB  . PHE B 1 48  ? 144.447 133.809 137.938 1.00 41.10  ? 48  PHE B CB  1 
ATOM   3473 C  CG  . PHE B 1 48  ? 143.563 134.610 138.852 1.00 47.94  ? 48  PHE B CG  1 
ATOM   3474 C  CD1 . PHE B 1 48  ? 144.082 135.646 139.610 1.00 46.58  ? 48  PHE B CD1 1 
ATOM   3475 C  CD2 . PHE B 1 48  ? 142.208 134.335 138.944 1.00 47.38  ? 48  PHE B CD2 1 
ATOM   3476 C  CE1 . PHE B 1 48  ? 143.267 136.387 140.445 1.00 45.40  ? 48  PHE B CE1 1 
ATOM   3477 C  CE2 . PHE B 1 48  ? 141.393 135.070 139.778 1.00 45.70  ? 48  PHE B CE2 1 
ATOM   3478 C  CZ  . PHE B 1 48  ? 141.923 136.096 140.530 1.00 42.47  ? 48  PHE B CZ  1 
ATOM   3479 N  N   . THR B 1 49  ? 143.564 131.342 139.755 1.00 40.26  ? 49  THR B N   1 
ATOM   3480 C  CA  . THR B 1 49  ? 142.799 130.891 140.915 1.00 40.99  ? 49  THR B CA  1 
ATOM   3481 C  C   . THR B 1 49  ? 143.678 130.136 141.901 1.00 42.61  ? 49  THR B C   1 
ATOM   3482 O  O   . THR B 1 49  ? 143.506 130.266 143.117 1.00 50.29  ? 49  THR B O   1 
ATOM   3483 C  CB  . THR B 1 49  ? 141.624 130.014 140.485 1.00 36.96  ? 49  THR B CB  1 
ATOM   3484 O  OG1 . THR B 1 49  ? 142.108 128.763 139.991 1.00 42.36  ? 49  THR B OG1 1 
ATOM   3485 C  CG2 . THR B 1 49  ? 140.811 130.696 139.414 1.00 37.37  ? 49  THR B CG2 1 
ATOM   3486 N  N   . ILE B 1 50  ? 144.614 129.333 141.400 1.00 36.85  ? 50  ILE B N   1 
ATOM   3487 C  CA  . ILE B 1 50  ? 145.457 128.541 142.289 1.00 37.65  ? 50  ILE B CA  1 
ATOM   3488 C  C   . ILE B 1 50  ? 146.431 129.432 143.047 1.00 46.22  ? 50  ILE B C   1 
ATOM   3489 O  O   . ILE B 1 50  ? 146.645 129.253 144.250 1.00 50.24  ? 50  ILE B O   1 
ATOM   3490 C  CB  . ILE B 1 50  ? 146.178 127.446 141.490 1.00 38.68  ? 50  ILE B CB  1 
ATOM   3491 C  CG1 . ILE B 1 50  ? 145.148 126.522 140.852 1.00 40.42  ? 50  ILE B CG1 1 
ATOM   3492 C  CG2 . ILE B 1 50  ? 147.104 126.657 142.387 1.00 38.51  ? 50  ILE B CG2 1 
ATOM   3493 C  CD1 . ILE B 1 50  ? 145.666 125.780 139.674 1.00 42.85  ? 50  ILE B CD1 1 
ATOM   3494 N  N   . VAL B 1 51  ? 147.040 130.403 142.364 1.00 45.07  ? 51  VAL B N   1 
ATOM   3495 C  CA  . VAL B 1 51  ? 147.947 131.316 143.049 1.00 43.85  ? 51  VAL B CA  1 
ATOM   3496 C  C   . VAL B 1 51  ? 147.179 132.266 143.962 1.00 46.99  ? 51  VAL B C   1 
ATOM   3497 O  O   . VAL B 1 51  ? 147.689 132.672 145.012 1.00 50.96  ? 51  VAL B O   1 
ATOM   3498 C  CB  . VAL B 1 51  ? 148.809 132.076 142.029 1.00 39.27  ? 51  VAL B CB  1 
ATOM   3499 C  CG1 . VAL B 1 51  ? 149.818 132.950 142.741 1.00 38.77  ? 51  VAL B CG1 1 
ATOM   3500 C  CG2 . VAL B 1 51  ? 149.517 131.097 141.122 1.00 42.64  ? 51  VAL B CG2 1 
ATOM   3501 N  N   . SER B 1 52  ? 145.956 132.644 143.585 1.00 41.87  ? 52  SER B N   1 
ATOM   3502 C  CA  . SER B 1 52  ? 145.129 133.448 144.478 1.00 39.87  ? 52  SER B CA  1 
ATOM   3503 C  C   . SER B 1 52  ? 144.828 132.693 145.763 1.00 49.22  ? 52  SER B C   1 
ATOM   3504 O  O   . SER B 1 52  ? 145.019 133.216 146.865 1.00 55.40  ? 52  SER B O   1 
ATOM   3505 C  CB  . SER B 1 52  ? 143.828 133.841 143.785 1.00 42.01  ? 52  SER B CB  1 
ATOM   3506 O  OG  . SER B 1 52  ? 144.061 134.185 142.438 1.00 51.04  ? 52  SER B OG  1 
ATOM   3507 N  N   . LEU B 1 53  ? 144.363 131.451 145.639 1.00 41.09  ? 53  LEU B N   1 
ATOM   3508 C  CA  . LEU B 1 53  ? 144.017 130.668 146.816 1.00 36.11  ? 53  LEU B CA  1 
ATOM   3509 C  C   . LEU B 1 53  ? 145.245 130.199 147.579 1.00 39.88  ? 53  LEU B C   1 
ATOM   3510 O  O   . LEU B 1 53  ? 145.145 129.936 148.780 1.00 49.86  ? 53  LEU B O   1 
ATOM   3511 C  CB  . LEU B 1 53  ? 143.154 129.475 146.415 1.00 40.08  ? 53  LEU B CB  1 
ATOM   3512 C  CG  . LEU B 1 53  ? 141.741 129.845 145.964 1.00 42.33  ? 53  LEU B CG  1 
ATOM   3513 C  CD1 . LEU B 1 53  ? 141.146 128.753 145.111 1.00 39.86  ? 53  LEU B CD1 1 
ATOM   3514 C  CD2 . LEU B 1 53  ? 140.856 130.128 147.159 1.00 42.55  ? 53  LEU B CD2 1 
ATOM   3515 N  N   . MET B 1 54  ? 146.395 130.081 146.917 1.00 45.99  ? 54  MET B N   1 
ATOM   3516 C  CA  . MET B 1 54  ? 147.621 129.756 147.637 1.00 49.23  ? 54  MET B CA  1 
ATOM   3517 C  C   . MET B 1 54  ? 148.008 130.874 148.593 1.00 51.28  ? 54  MET B C   1 
ATOM   3518 O  O   . MET B 1 54  ? 148.446 130.615 149.719 1.00 55.56  ? 54  MET B O   1 
ATOM   3519 C  CB  . MET B 1 54  ? 148.755 129.475 146.654 1.00 46.52  ? 54  MET B CB  1 
ATOM   3520 C  CG  . MET B 1 54  ? 149.109 128.009 146.532 1.00 48.45  ? 54  MET B CG  1 
ATOM   3521 S  SD  . MET B 1 54  ? 150.119 127.655 145.088 1.00 65.91  ? 54  MET B SD  1 
ATOM   3522 C  CE  . MET B 1 54  ? 150.882 126.116 145.590 1.00 56.86  ? 54  MET B CE  1 
ATOM   3523 N  N   . TYR B 1 55  ? 147.858 132.127 148.164 1.00 48.76  ? 55  TYR B N   1 
ATOM   3524 C  CA  . TYR B 1 55  ? 148.173 133.245 149.043 1.00 51.61  ? 55  TYR B CA  1 
ATOM   3525 C  C   . TYR B 1 55  ? 147.222 133.300 150.233 1.00 57.01  ? 55  TYR B C   1 
ATOM   3526 O  O   . TYR B 1 55  ? 147.620 133.696 151.333 1.00 59.15  ? 55  TYR B O   1 
ATOM   3527 C  CB  . TYR B 1 55  ? 148.131 134.557 148.265 1.00 49.45  ? 55  TYR B CB  1 
ATOM   3528 C  CG  . TYR B 1 55  ? 148.391 135.770 149.126 1.00 57.93  ? 55  TYR B CG  1 
ATOM   3529 C  CD1 . TYR B 1 55  ? 149.669 136.059 149.581 1.00 57.34  ? 55  TYR B CD1 1 
ATOM   3530 C  CD2 . TYR B 1 55  ? 147.357 136.619 149.495 1.00 56.55  ? 55  TYR B CD2 1 
ATOM   3531 C  CE1 . TYR B 1 55  ? 149.911 137.160 150.370 1.00 58.74  ? 55  TYR B CE1 1 
ATOM   3532 C  CE2 . TYR B 1 55  ? 147.590 137.723 150.287 1.00 58.15  ? 55  TYR B CE2 1 
ATOM   3533 C  CZ  . TYR B 1 55  ? 148.868 137.989 150.722 1.00 62.36  ? 55  TYR B CZ  1 
ATOM   3534 O  OH  . TYR B 1 55  ? 149.106 139.089 151.512 1.00 62.11  ? 55  TYR B OH  1 
ATOM   3535 N  N   . PHE B 1 56  ? 145.961 132.918 150.035 1.00 54.59  ? 56  PHE B N   1 
ATOM   3536 C  CA  . PHE B 1 56  ? 144.986 132.958 151.117 1.00 52.13  ? 56  PHE B CA  1 
ATOM   3537 C  C   . PHE B 1 56  ? 145.002 131.706 151.981 1.00 54.67  ? 56  PHE B C   1 
ATOM   3538 O  O   . PHE B 1 56  ? 144.535 131.755 153.122 1.00 55.71  ? 56  PHE B O   1 
ATOM   3539 C  CB  . PHE B 1 56  ? 143.581 133.168 150.555 1.00 54.31  ? 56  PHE B CB  1 
ATOM   3540 C  CG  . PHE B 1 56  ? 143.381 134.506 149.913 1.00 56.22  ? 56  PHE B CG  1 
ATOM   3541 C  CD1 . PHE B 1 56  ? 143.665 135.668 150.604 1.00 57.28  ? 56  PHE B CD1 1 
ATOM   3542 C  CD2 . PHE B 1 56  ? 142.905 134.603 148.621 1.00 52.17  ? 56  PHE B CD2 1 
ATOM   3543 C  CE1 . PHE B 1 56  ? 143.484 136.898 150.016 1.00 57.02  ? 56  PHE B CE1 1 
ATOM   3544 C  CE2 . PHE B 1 56  ? 142.721 135.829 148.030 1.00 53.09  ? 56  PHE B CE2 1 
ATOM   3545 C  CZ  . PHE B 1 56  ? 143.011 136.979 148.729 1.00 54.42  ? 56  PHE B CZ  1 
ATOM   3546 N  N   . ALA B 1 57  ? 145.513 130.588 151.471 1.00 47.95  ? 57  ALA B N   1 
ATOM   3547 C  CA  . ALA B 1 57  ? 145.590 129.363 152.252 1.00 44.06  ? 57  ALA B CA  1 
ATOM   3548 C  C   . ALA B 1 57  ? 146.885 129.237 153.036 1.00 48.83  ? 57  ALA B C   1 
ATOM   3549 O  O   . ALA B 1 57  ? 147.023 128.296 153.822 1.00 56.16  ? 57  ALA B O   1 
ATOM   3550 C  CB  . ALA B 1 57  ? 145.431 128.138 151.349 1.00 42.89  ? 57  ALA B CB  1 
ATOM   3551 N  N   . PHE B 1 58  ? 147.835 130.151 152.845 1.00 45.92  ? 58  PHE B N   1 
ATOM   3552 C  CA  . PHE B 1 58  ? 149.112 130.082 153.537 1.00 49.08  ? 58  PHE B CA  1 
ATOM   3553 C  C   . PHE B 1 58  ? 149.485 131.355 154.277 1.00 50.66  ? 58  PHE B C   1 
ATOM   3554 O  O   . PHE B 1 58  ? 150.393 131.309 155.113 1.00 56.18  ? 58  PHE B O   1 
ATOM   3555 C  CB  . PHE B 1 58  ? 150.239 129.736 152.551 1.00 49.28  ? 58  PHE B CB  1 
ATOM   3556 C  CG  . PHE B 1 58  ? 150.079 128.394 151.896 1.00 49.27  ? 58  PHE B CG  1 
ATOM   3557 C  CD1 . PHE B 1 58  ? 149.810 127.269 152.651 1.00 47.06  ? 58  PHE B CD1 1 
ATOM   3558 C  CD2 . PHE B 1 58  ? 150.201 128.258 150.527 1.00 49.16  ? 58  PHE B CD2 1 
ATOM   3559 C  CE1 . PHE B 1 58  ? 149.662 126.041 152.051 1.00 46.89  ? 58  PHE B CE1 1 
ATOM   3560 C  CE2 . PHE B 1 58  ? 150.053 127.029 149.924 1.00 49.53  ? 58  PHE B CE2 1 
ATOM   3561 C  CZ  . PHE B 1 58  ? 149.784 125.921 150.687 1.00 51.27  ? 58  PHE B CZ  1 
ATOM   3562 N  N   . THR B 1 59  ? 148.827 132.479 154.010 1.00 52.49  ? 59  THR B N   1 
ATOM   3563 C  CA  . THR B 1 59  ? 149.135 133.737 154.674 1.00 53.98  ? 59  THR B CA  1 
ATOM   3564 C  C   . THR B 1 59  ? 147.995 134.285 155.516 1.00 51.66  ? 59  THR B C   1 
ATOM   3565 O  O   . THR B 1 59  ? 148.255 135.016 156.472 1.00 50.69  ? 59  THR B O   1 
ATOM   3566 C  CB  . THR B 1 59  ? 149.531 134.807 153.648 1.00 52.69  ? 59  THR B CB  1 
ATOM   3567 O  OG1 . THR B 1 59  ? 148.372 135.206 152.909 1.00 58.12  ? 59  THR B OG1 1 
ATOM   3568 C  CG2 . THR B 1 59  ? 150.571 134.265 152.686 1.00 48.97  ? 59  THR B CG2 1 
ATOM   3569 N  N   . ARG B 1 60  ? 146.749 133.965 155.185 1.00 54.87  ? 60  ARG B N   1 
ATOM   3570 C  CA  . ARG B 1 60  ? 145.621 134.455 155.964 1.00 53.61  ? 60  ARG B CA  1 
ATOM   3571 C  C   . ARG B 1 60  ? 145.619 133.839 157.355 1.00 54.55  ? 60  ARG B C   1 
ATOM   3572 O  O   . ARG B 1 60  ? 145.815 132.632 157.519 1.00 59.00  ? 60  ARG B O   1 
ATOM   3573 C  CB  . ARG B 1 60  ? 144.309 134.138 155.252 1.00 51.90  ? 60  ARG B CB  1 
ATOM   3574 C  CG  . ARG B 1 60  ? 143.304 135.265 155.302 1.00 57.19  ? 60  ARG B CG  1 
ATOM   3575 C  CD  . ARG B 1 60  ? 141.930 134.797 154.887 1.00 57.05  ? 60  ARG B CD  1 
ATOM   3576 N  NE  . ARG B 1 60  ? 141.544 133.571 155.569 1.00 56.44  ? 60  ARG B NE  1 
ATOM   3577 C  CZ  . ARG B 1 60  ? 140.763 133.527 156.637 1.00 52.78  ? 60  ARG B CZ  1 
ATOM   3578 N  NH1 . ARG B 1 60  ? 140.293 134.629 157.195 1.00 49.50  ? 60  ARG B NH1 1 
ATOM   3579 N  NH2 . ARG B 1 60  ? 140.447 132.347 157.160 1.00 54.27  ? 60  ARG B NH2 1 
ATOM   3580 N  N   . ASP B 1 61  ? 145.393 134.677 158.362 1.00 57.23  ? 61  ASP B N   1 
ATOM   3581 C  CA  . ASP B 1 61  ? 145.280 134.203 159.736 1.00 57.53  ? 61  ASP B CA  1 
ATOM   3582 C  C   . ASP B 1 61  ? 143.857 133.716 159.961 1.00 62.80  ? 61  ASP B C   1 
ATOM   3583 O  O   . ASP B 1 61  ? 142.907 134.503 159.911 1.00 63.78  ? 61  ASP B O   1 
ATOM   3584 C  CB  . ASP B 1 61  ? 145.648 135.306 160.723 1.00 56.36  ? 61  ASP B CB  1 
ATOM   3585 C  CG  . ASP B 1 61  ? 145.598 134.834 162.162 1.00 60.66  ? 61  ASP B CG  1 
ATOM   3586 O  OD1 . ASP B 1 61  ? 146.409 133.960 162.528 1.00 62.82  ? 61  ASP B OD1 1 
ATOM   3587 O  OD2 . ASP B 1 61  ? 144.749 135.335 162.928 1.00 61.13  ? 61  ASP B OD2 1 
ATOM   3588 N  N   . ASP B 1 62  ? 143.709 132.419 160.211 1.00 58.11  ? 62  ASP B N   1 
ATOM   3589 C  CA  . ASP B 1 62  ? 142.414 131.780 160.398 1.00 53.14  ? 62  ASP B CA  1 
ATOM   3590 C  C   . ASP B 1 62  ? 142.195 131.395 161.856 1.00 56.40  ? 62  ASP B C   1 
ATOM   3591 O  O   . ASP B 1 62  ? 141.639 130.340 162.163 1.00 53.37  ? 62  ASP B O   1 
ATOM   3592 C  CB  . ASP B 1 62  ? 142.288 130.559 159.494 1.00 52.74  ? 62  ASP B CB  1 
ATOM   3593 C  CG  . ASP B 1 62  ? 143.454 129.607 159.642 1.00 60.35  ? 62  ASP B CG  1 
ATOM   3594 O  OD1 . ASP B 1 62  ? 144.396 129.937 160.390 1.00 62.45  ? 62  ASP B OD1 1 
ATOM   3595 O  OD2 . ASP B 1 62  ? 143.434 128.531 159.010 1.00 62.71  ? 62  ASP B OD2 1 
ATOM   3596 N  N   . SER B 1 63  ? 142.639 132.255 162.771 1.00 62.29  ? 63  SER B N   1 
ATOM   3597 C  CA  . SER B 1 63  ? 142.552 131.980 164.197 1.00 62.19  ? 63  SER B CA  1 
ATOM   3598 C  C   . SER B 1 63  ? 141.194 132.317 164.792 1.00 61.04  ? 63  SER B C   1 
ATOM   3599 O  O   . SER B 1 63  ? 140.931 131.935 165.936 1.00 63.25  ? 63  SER B O   1 
ATOM   3600 C  CB  . SER B 1 63  ? 143.637 132.756 164.943 1.00 65.86  ? 63  SER B CB  1 
ATOM   3601 O  OG  . SER B 1 63  ? 143.578 134.135 164.626 1.00 66.62  ? 63  SER B OG  1 
ATOM   3602 N  N   . VAL B 1 64  ? 140.336 133.025 164.064 1.00 59.01  ? 64  VAL B N   1 
ATOM   3603 C  CA  . VAL B 1 64  ? 138.987 133.304 164.549 1.00 60.63  ? 64  VAL B CA  1 
ATOM   3604 C  C   . VAL B 1 64  ? 138.002 132.530 163.680 1.00 61.65  ? 64  VAL B C   1 
ATOM   3605 O  O   . VAL B 1 64  ? 138.140 132.501 162.448 1.00 63.81  ? 64  VAL B O   1 
ATOM   3606 C  CB  . VAL B 1 64  ? 138.693 134.816 164.576 1.00 61.79  ? 64  VAL B CB  1 
ATOM   3607 C  CG1 . VAL B 1 64  ? 139.884 135.575 165.130 1.00 62.62  ? 64  VAL B CG1 1 
ATOM   3608 C  CG2 . VAL B 1 64  ? 138.334 135.346 163.207 1.00 62.12  ? 64  VAL B CG2 1 
ATOM   3609 N  N   . PRO B 1 65  ? 137.034 131.833 164.278 1.00 58.02  ? 65  PRO B N   1 
ATOM   3610 C  CA  . PRO B 1 65  ? 136.082 131.062 163.468 1.00 55.99  ? 65  PRO B CA  1 
ATOM   3611 C  C   . PRO B 1 65  ? 134.985 131.902 162.847 1.00 60.29  ? 65  PRO B C   1 
ATOM   3612 O  O   . PRO B 1 65  ? 134.328 131.435 161.909 1.00 61.34  ? 65  PRO B O   1 
ATOM   3613 C  CB  . PRO B 1 65  ? 135.497 130.057 164.474 1.00 56.15  ? 65  PRO B CB  1 
ATOM   3614 C  CG  . PRO B 1 65  ? 136.415 130.107 165.664 1.00 60.35  ? 65  PRO B CG  1 
ATOM   3615 C  CD  . PRO B 1 65  ? 136.920 131.507 165.704 1.00 62.99  ? 65  PRO B CD  1 
ATOM   3616 N  N   . GLU B 1 66  ? 134.756 133.116 163.344 1.00 66.72  ? 66  GLU B N   1 
ATOM   3617 C  CA  . GLU B 1 66  ? 133.670 133.934 162.820 1.00 64.99  ? 66  GLU B CA  1 
ATOM   3618 C  C   . GLU B 1 66  ? 134.023 134.515 161.457 1.00 64.72  ? 66  GLU B C   1 
ATOM   3619 O  O   . GLU B 1 66  ? 133.179 134.556 160.556 1.00 63.01  ? 66  GLU B O   1 
ATOM   3620 C  CB  . GLU B 1 66  ? 133.337 135.048 163.810 1.00 65.19  ? 66  GLU B CB  1 
ATOM   3621 C  CG  . GLU B 1 66  ? 132.370 134.631 164.903 1.00 66.71  ? 66  GLU B CG  1 
ATOM   3622 C  CD  . GLU B 1 66  ? 133.036 133.792 165.977 1.00 68.89  ? 66  GLU B CD  1 
ATOM   3623 O  OE1 . GLU B 1 66  ? 132.350 132.939 166.576 1.00 69.39  ? 66  GLU B OE1 1 
ATOM   3624 O  OE2 . GLU B 1 66  ? 134.243 133.988 166.227 1.00 66.75  ? 66  GLU B OE2 1 
ATOM   3625 N  N   . ASP B 1 67  ? 135.263 134.970 161.288 1.00 61.04  ? 67  ASP B N   1 
ATOM   3626 C  CA  . ASP B 1 67  ? 135.704 135.594 160.049 1.00 59.51  ? 67  ASP B CA  1 
ATOM   3627 C  C   . ASP B 1 67  ? 136.183 134.584 159.021 1.00 61.59  ? 67  ASP B C   1 
ATOM   3628 O  O   . ASP B 1 67  ? 136.407 134.958 157.866 1.00 66.16  ? 67  ASP B O   1 
ATOM   3629 C  CB  . ASP B 1 67  ? 136.823 136.599 160.335 1.00 59.96  ? 67  ASP B CB  1 
ATOM   3630 C  CG  . ASP B 1 67  ? 136.786 137.800 159.409 1.00 66.56  ? 67  ASP B CG  1 
ATOM   3631 O  OD1 . ASP B 1 67  ? 136.421 138.898 159.879 1.00 66.44  ? 67  ASP B OD1 1 
ATOM   3632 O  OD2 . ASP B 1 67  ? 137.122 137.654 158.215 1.00 67.83  ? 67  ASP B OD2 1 
ATOM   3633 N  N   . ASN B 1 68  ? 136.358 133.322 159.410 1.00 54.65  ? 68  ASN B N   1 
ATOM   3634 C  CA  . ASN B 1 68  ? 136.706 132.292 158.438 1.00 45.54  ? 68  ASN B CA  1 
ATOM   3635 C  C   . ASN B 1 68  ? 135.494 131.885 157.616 1.00 49.36  ? 68  ASN B C   1 
ATOM   3636 O  O   . ASN B 1 68  ? 135.605 131.645 156.410 1.00 55.64  ? 68  ASN B O   1 
ATOM   3637 C  CB  . ASN B 1 68  ? 137.300 131.085 159.152 1.00 42.81  ? 68  ASN B CB  1 
ATOM   3638 C  CG  . ASN B 1 68  ? 138.668 131.365 159.712 1.00 50.19  ? 68  ASN B CG  1 
ATOM   3639 O  OD1 . ASN B 1 68  ? 139.412 132.181 159.175 1.00 58.42  ? 68  ASN B OD1 1 
ATOM   3640 N  ND2 . ASN B 1 68  ? 139.010 130.695 160.798 1.00 49.47  ? 68  ASN B ND2 1 
ATOM   3641 N  N   . ILE B 1 69  ? 134.329 131.799 158.255 1.00 47.01  ? 69  ILE B N   1 
ATOM   3642 C  CA  . ILE B 1 69  ? 133.109 131.454 157.537 1.00 47.72  ? 69  ILE B CA  1 
ATOM   3643 C  C   . ILE B 1 69  ? 132.711 132.578 156.595 1.00 48.90  ? 69  ILE B C   1 
ATOM   3644 O  O   . ILE B 1 69  ? 132.198 132.332 155.499 1.00 53.98  ? 69  ILE B O   1 
ATOM   3645 C  CB  . ILE B 1 69  ? 131.987 131.114 158.532 1.00 48.90  ? 69  ILE B CB  1 
ATOM   3646 C  CG1 . ILE B 1 69  ? 132.396 129.920 159.392 1.00 50.24  ? 69  ILE B CG1 1 
ATOM   3647 C  CG2 . ILE B 1 69  ? 130.695 130.819 157.803 1.00 48.63  ? 69  ILE B CG2 1 
ATOM   3648 C  CD1 . ILE B 1 69  ? 131.358 129.518 160.399 1.00 50.16  ? 69  ILE B CD1 1 
ATOM   3649 N  N   . TRP B 1 70  ? 132.933 133.828 157.001 1.00 45.73  ? 70  TRP B N   1 
ATOM   3650 C  CA  . TRP B 1 70  ? 132.572 134.952 156.144 1.00 44.07  ? 70  TRP B CA  1 
ATOM   3651 C  C   . TRP B 1 70  ? 133.440 134.996 154.894 1.00 41.79  ? 70  TRP B C   1 
ATOM   3652 O  O   . TRP B 1 70  ? 132.929 135.119 153.777 1.00 46.18  ? 70  TRP B O   1 
ATOM   3653 C  CB  . TRP B 1 70  ? 132.678 136.262 156.921 1.00 43.05  ? 70  TRP B CB  1 
ATOM   3654 C  CG  . TRP B 1 70  ? 132.260 137.461 156.131 1.00 45.20  ? 70  TRP B CG  1 
ATOM   3655 C  CD1 . TRP B 1 70  ? 132.965 138.611 155.962 1.00 44.77  ? 70  TRP B CD1 1 
ATOM   3656 C  CD2 . TRP B 1 70  ? 131.035 137.632 155.404 1.00 48.70  ? 70  TRP B CD2 1 
ATOM   3657 N  NE1 . TRP B 1 70  ? 132.262 139.486 155.173 1.00 43.21  ? 70  TRP B NE1 1 
ATOM   3658 C  CE2 . TRP B 1 70  ? 131.072 138.909 154.821 1.00 44.22  ? 70  TRP B CE2 1 
ATOM   3659 C  CE3 . TRP B 1 70  ? 129.911 136.828 155.190 1.00 44.68  ? 70  TRP B CE3 1 
ATOM   3660 C  CZ2 . TRP B 1 70  ? 130.035 139.399 154.039 1.00 46.34  ? 70  TRP B CZ2 1 
ATOM   3661 C  CZ3 . TRP B 1 70  ? 128.885 137.317 154.416 1.00 41.20  ? 70  TRP B CZ3 1 
ATOM   3662 C  CH2 . TRP B 1 70  ? 128.952 138.590 153.850 1.00 44.49  ? 70  TRP B CH2 1 
ATOM   3663 N  N   . ARG B 1 71  ? 134.759 134.893 155.058 1.00 42.45  ? 71  ARG B N   1 
ATOM   3664 C  CA  . ARG B 1 71  ? 135.642 134.945 153.899 1.00 41.30  ? 71  ARG B CA  1 
ATOM   3665 C  C   . ARG B 1 71  ? 135.504 133.705 153.029 1.00 46.52  ? 71  ARG B C   1 
ATOM   3666 O  O   . ARG B 1 71  ? 135.771 133.765 151.824 1.00 50.20  ? 71  ARG B O   1 
ATOM   3667 C  CB  . ARG B 1 71  ? 137.089 135.131 154.344 1.00 41.10  ? 71  ARG B CB  1 
ATOM   3668 C  CG  . ARG B 1 71  ? 137.420 136.557 154.731 1.00 43.52  ? 71  ARG B CG  1 
ATOM   3669 C  CD  . ARG B 1 71  ? 138.480 137.142 153.811 1.00 49.31  ? 71  ARG B CD  1 
ATOM   3670 N  NE  . ARG B 1 71  ? 138.172 136.922 152.402 1.00 54.18  ? 71  ARG B NE  1 
ATOM   3671 C  CZ  . ARG B 1 71  ? 138.935 137.325 151.394 1.00 54.00  ? 71  ARG B CZ  1 
ATOM   3672 N  NH1 . ARG B 1 71  ? 140.062 137.984 151.601 1.00 51.49  ? 71  ARG B NH1 1 
ATOM   3673 N  NH2 . ARG B 1 71  ? 138.557 137.058 150.147 1.00 43.46  ? 71  ARG B NH2 1 
ATOM   3674 N  N   . GLY B 1 72  ? 135.107 132.575 153.612 1.00 38.58  ? 72  GLY B N   1 
ATOM   3675 C  CA  . GLY B 1 72  ? 134.822 131.403 152.803 1.00 37.32  ? 72  GLY B CA  1 
ATOM   3676 C  C   . GLY B 1 72  ? 133.589 131.582 151.940 1.00 42.10  ? 72  GLY B C   1 
ATOM   3677 O  O   . GLY B 1 72  ? 133.563 131.155 150.785 1.00 43.74  ? 72  GLY B O   1 
ATOM   3678 N  N   . ILE B 1 73  ? 132.547 132.205 152.493 1.00 41.90  ? 73  ILE B N   1 
ATOM   3679 C  CA  . ILE B 1 73  ? 131.344 132.500 151.720 1.00 33.76  ? 73  ILE B CA  1 
ATOM   3680 C  C   . ILE B 1 73  ? 131.655 133.480 150.600 1.00 36.97  ? 73  ILE B C   1 
ATOM   3681 O  O   . ILE B 1 73  ? 131.180 133.322 149.471 1.00 44.90  ? 73  ILE B O   1 
ATOM   3682 C  CB  . ILE B 1 73  ? 130.239 133.037 152.645 1.00 33.61  ? 73  ILE B CB  1 
ATOM   3683 C  CG1 . ILE B 1 73  ? 129.765 131.949 153.601 1.00 44.32  ? 73  ILE B CG1 1 
ATOM   3684 C  CG2 . ILE B 1 73  ? 129.075 133.564 151.840 1.00 32.21  ? 73  ILE B CG2 1 
ATOM   3685 C  CD1 . ILE B 1 73  ? 128.848 132.461 154.670 1.00 43.53  ? 73  ILE B CD1 1 
ATOM   3686 N  N   . LEU B 1 74  ? 132.446 134.513 150.893 1.00 36.00  ? 74  LEU B N   1 
ATOM   3687 C  CA  . LEU B 1 74  ? 132.804 135.492 149.873 1.00 30.90  ? 74  LEU B CA  1 
ATOM   3688 C  C   . LEU B 1 74  ? 133.614 134.854 148.755 1.00 36.09  ? 74  LEU B C   1 
ATOM   3689 O  O   . LEU B 1 74  ? 133.499 135.252 147.591 1.00 43.20  ? 74  LEU B O   1 
ATOM   3690 C  CB  . LEU B 1 74  ? 133.585 136.641 150.503 1.00 32.20  ? 74  LEU B CB  1 
ATOM   3691 C  CG  . LEU B 1 74  ? 132.826 137.558 151.455 1.00 30.01  ? 74  LEU B CG  1 
ATOM   3692 C  CD1 . LEU B 1 74  ? 133.644 138.796 151.742 1.00 34.11  ? 74  LEU B CD1 1 
ATOM   3693 C  CD2 . LEU B 1 74  ? 131.487 137.930 150.865 1.00 38.13  ? 74  LEU B CD2 1 
ATOM   3694 N  N   . SER B 1 75  ? 134.452 133.873 149.089 1.00 35.70  ? 75  SER B N   1 
ATOM   3695 C  CA  . SER B 1 75  ? 135.280 133.229 148.076 1.00 34.25  ? 75  SER B CA  1 
ATOM   3696 C  C   . SER B 1 75  ? 134.477 132.244 147.240 1.00 33.26  ? 75  SER B C   1 
ATOM   3697 O  O   . SER B 1 75  ? 134.749 132.071 146.049 1.00 39.78  ? 75  SER B O   1 
ATOM   3698 C  CB  . SER B 1 75  ? 136.462 132.535 148.737 1.00 36.11  ? 75  SER B CB  1 
ATOM   3699 O  OG  . SER B 1 75  ? 137.583 133.396 148.756 1.00 51.13  ? 75  SER B OG  1 
ATOM   3700 N  N   . VAL B 1 76  ? 133.498 131.573 147.846 1.00 31.92  ? 76  VAL B N   1 
ATOM   3701 C  CA  . VAL B 1 76  ? 132.621 130.698 147.076 1.00 24.19  ? 76  VAL B CA  1 
ATOM   3702 C  C   . VAL B 1 76  ? 131.796 131.511 146.088 1.00 32.94  ? 76  VAL B C   1 
ATOM   3703 O  O   . VAL B 1 76  ? 131.591 131.100 144.941 1.00 40.06  ? 76  VAL B O   1 
ATOM   3704 C  CB  . VAL B 1 76  ? 131.731 129.872 148.020 1.00 28.61  ? 76  VAL B CB  1 
ATOM   3705 C  CG1 . VAL B 1 76  ? 130.584 129.254 147.258 1.00 32.12  ? 76  VAL B CG1 1 
ATOM   3706 C  CG2 . VAL B 1 76  ? 132.545 128.802 148.709 1.00 30.81  ? 76  VAL B CG2 1 
ATOM   3707 N  N   . ILE B 1 77  ? 131.304 132.674 146.516 1.00 34.46  ? 77  ILE B N   1 
ATOM   3708 C  CA  . ILE B 1 77  ? 130.556 133.545 145.614 1.00 29.28  ? 77  ILE B CA  1 
ATOM   3709 C  C   . ILE B 1 77  ? 131.455 134.063 144.501 1.00 26.67  ? 77  ILE B C   1 
ATOM   3710 O  O   . ILE B 1 77  ? 131.058 134.103 143.333 1.00 32.79  ? 77  ILE B O   1 
ATOM   3711 C  CB  . ILE B 1 77  ? 129.911 134.700 146.401 1.00 26.44  ? 77  ILE B CB  1 
ATOM   3712 C  CG1 . ILE B 1 77  ? 128.877 134.165 147.387 1.00 27.40  ? 77  ILE B CG1 1 
ATOM   3713 C  CG2 . ILE B 1 77  ? 129.269 135.690 145.458 1.00 33.18  ? 77  ILE B CG2 1 
ATOM   3714 C  CD1 . ILE B 1 77  ? 128.353 135.212 148.328 1.00 29.50  ? 77  ILE B CD1 1 
ATOM   3715 N  N   . PHE B 1 78  ? 132.675 134.480 144.843 1.00 29.50  ? 78  PHE B N   1 
ATOM   3716 C  CA  . PHE B 1 78  ? 133.580 135.029 143.839 1.00 25.30  ? 78  PHE B CA  1 
ATOM   3717 C  C   . PHE B 1 78  ? 133.985 133.973 142.821 1.00 34.17  ? 78  PHE B C   1 
ATOM   3718 O  O   . PHE B 1 78  ? 133.985 134.231 141.614 1.00 43.20  ? 78  PHE B O   1 
ATOM   3719 C  CB  . PHE B 1 78  ? 134.818 135.620 144.508 1.00 26.21  ? 78  PHE B CB  1 
ATOM   3720 C  CG  . PHE B 1 78  ? 135.886 136.037 143.540 1.00 29.74  ? 78  PHE B CG  1 
ATOM   3721 C  CD1 . PHE B 1 78  ? 135.788 137.228 142.852 1.00 37.53  ? 78  PHE B CD1 1 
ATOM   3722 C  CD2 . PHE B 1 78  ? 136.984 135.234 143.314 1.00 33.06  ? 78  PHE B CD2 1 
ATOM   3723 C  CE1 . PHE B 1 78  ? 136.767 137.610 141.963 1.00 36.36  ? 78  PHE B CE1 1 
ATOM   3724 C  CE2 . PHE B 1 78  ? 137.963 135.612 142.424 1.00 29.78  ? 78  PHE B CE2 1 
ATOM   3725 C  CZ  . PHE B 1 78  ? 137.853 136.800 141.750 1.00 29.75  ? 78  PHE B CZ  1 
ATOM   3726 N  N   . PHE B 1 79  ? 134.339 132.777 143.285 1.00 33.70  ? 79  PHE B N   1 
ATOM   3727 C  CA  . PHE B 1 79  ? 134.805 131.739 142.379 1.00 22.17  ? 79  PHE B CA  1 
ATOM   3728 C  C   . PHE B 1 79  ? 133.671 131.035 141.653 1.00 25.34  ? 79  PHE B C   1 
ATOM   3729 O  O   . PHE B 1 79  ? 133.935 130.304 140.696 1.00 41.50  ? 79  PHE B O   1 
ATOM   3730 C  CB  . PHE B 1 79  ? 135.657 130.724 143.137 1.00 27.30  ? 79  PHE B CB  1 
ATOM   3731 C  CG  . PHE B 1 79  ? 137.062 131.184 143.371 1.00 33.66  ? 79  PHE B CG  1 
ATOM   3732 C  CD1 . PHE B 1 79  ? 137.975 131.204 142.337 1.00 34.66  ? 79  PHE B CD1 1 
ATOM   3733 C  CD2 . PHE B 1 79  ? 137.466 131.620 144.618 1.00 33.50  ? 79  PHE B CD2 1 
ATOM   3734 C  CE1 . PHE B 1 79  ? 139.260 131.639 142.545 1.00 37.44  ? 79  PHE B CE1 1 
ATOM   3735 C  CE2 . PHE B 1 79  ? 138.754 132.052 144.829 1.00 29.80  ? 79  PHE B CE2 1 
ATOM   3736 C  CZ  . PHE B 1 79  ? 139.651 132.062 143.791 1.00 33.34  ? 79  PHE B CZ  1 
ATOM   3737 N  N   . PHE B 1 80  ? 132.426 131.224 142.083 1.00 18.23  ? 80  PHE B N   1 
ATOM   3738 C  CA  . PHE B 1 80  ? 131.298 130.816 141.259 1.00 19.87  ? 80  PHE B CA  1 
ATOM   3739 C  C   . PHE B 1 80  ? 131.067 131.791 140.117 1.00 27.88  ? 80  PHE B C   1 
ATOM   3740 O  O   . PHE B 1 80  ? 130.516 131.409 139.081 1.00 29.02  ? 80  PHE B O   1 
ATOM   3741 C  CB  . PHE B 1 80  ? 130.032 130.694 142.102 1.00 18.35  ? 80  PHE B CB  1 
ATOM   3742 C  CG  . PHE B 1 80  ? 128.906 130.001 141.398 1.00 22.61  ? 80  PHE B CG  1 
ATOM   3743 C  CD1 . PHE B 1 80  ? 129.045 128.700 140.958 1.00 24.42  ? 80  PHE B CD1 1 
ATOM   3744 C  CD2 . PHE B 1 80  ? 127.710 130.648 141.175 1.00 19.68  ? 80  PHE B CD2 1 
ATOM   3745 C  CE1 . PHE B 1 80  ? 128.013 128.061 140.315 1.00 25.20  ? 80  PHE B CE1 1 
ATOM   3746 C  CE2 . PHE B 1 80  ? 126.677 130.012 140.531 1.00 19.26  ? 80  PHE B CE2 1 
ATOM   3747 C  CZ  . PHE B 1 80  ? 126.829 128.718 140.102 1.00 22.11  ? 80  PHE B CZ  1 
ATOM   3748 N  N   . LEU B 1 81  ? 131.469 133.050 140.289 1.00 29.81  ? 81  LEU B N   1 
ATOM   3749 C  CA  . LEU B 1 81  ? 131.408 134.000 139.187 1.00 19.17  ? 81  LEU B CA  1 
ATOM   3750 C  C   . LEU B 1 81  ? 132.475 133.707 138.142 1.00 25.45  ? 81  LEU B C   1 
ATOM   3751 O  O   . LEU B 1 81  ? 132.271 133.984 136.957 1.00 32.15  ? 81  LEU B O   1 
ATOM   3752 C  CB  . LEU B 1 81  ? 131.555 135.425 139.714 1.00 27.05  ? 81  LEU B CB  1 
ATOM   3753 C  CG  . LEU B 1 81  ? 130.475 135.939 140.665 1.00 29.05  ? 81  LEU B CG  1 
ATOM   3754 C  CD1 . LEU B 1 81  ? 130.468 137.452 140.673 1.00 28.28  ? 81  LEU B CD1 1 
ATOM   3755 C  CD2 . LEU B 1 81  ? 129.113 135.403 140.294 1.00 20.88  ? 81  LEU B CD2 1 
ATOM   3756 N  N   . ILE B 1 82  ? 133.620 133.166 138.561 1.00 28.35  ? 82  ILE B N   1 
ATOM   3757 C  CA  . ILE B 1 82  ? 134.652 132.758 137.614 1.00 26.31  ? 82  ILE B CA  1 
ATOM   3758 C  C   . ILE B 1 82  ? 134.212 131.521 136.841 1.00 23.50  ? 82  ILE B C   1 
ATOM   3759 O  O   . ILE B 1 82  ? 134.473 131.399 135.640 1.00 34.84  ? 82  ILE B O   1 
ATOM   3760 C  CB  . ILE B 1 82  ? 135.984 132.533 138.351 1.00 30.04  ? 82  ILE B CB  1 
ATOM   3761 C  CG1 . ILE B 1 82  ? 136.709 133.862 138.547 1.00 30.36  ? 82  ILE B CG1 1 
ATOM   3762 C  CG2 . ILE B 1 82  ? 136.866 131.560 137.602 1.00 29.05  ? 82  ILE B CG2 1 
ATOM   3763 C  CD1 . ILE B 1 82  ? 138.023 133.729 139.260 1.00 29.55  ? 82  ILE B CD1 1 
ATOM   3764 N  N   . ILE B 1 83  ? 133.548 130.580 137.513 1.00 18.54  ? 83  ILE B N   1 
ATOM   3765 C  CA  . ILE B 1 83  ? 133.007 129.412 136.823 1.00 21.38  ? 83  ILE B CA  1 
ATOM   3766 C  C   . ILE B 1 83  ? 131.888 129.821 135.875 1.00 26.19  ? 83  ILE B C   1 
ATOM   3767 O  O   . ILE B 1 83  ? 131.743 129.260 134.783 1.00 32.39  ? 83  ILE B O   1 
ATOM   3768 C  CB  . ILE B 1 83  ? 132.531 128.362 137.843 1.00 28.95  ? 83  ILE B CB  1 
ATOM   3769 C  CG1 . ILE B 1 83  ? 133.687 127.449 138.246 1.00 27.68  ? 83  ILE B CG1 1 
ATOM   3770 C  CG2 . ILE B 1 83  ? 131.371 127.554 137.288 1.00 23.94  ? 83  ILE B CG2 1 
ATOM   3771 C  CD1 . ILE B 1 83  ? 133.985 126.372 137.239 1.00 26.71  ? 83  ILE B CD1 1 
ATOM   3772 N  N   . SER B 1 84  ? 131.082 130.806 136.269 1.00 27.28  ? 84  SER B N   1 
ATOM   3773 C  CA  . SER B 1 84  ? 129.983 131.250 135.421 1.00 22.61  ? 84  SER B CA  1 
ATOM   3774 C  C   . SER B 1 84  ? 130.481 131.910 134.143 1.00 23.56  ? 84  SER B C   1 
ATOM   3775 O  O   . SER B 1 84  ? 129.790 131.870 133.122 1.00 29.40  ? 84  SER B O   1 
ATOM   3776 C  CB  . SER B 1 84  ? 129.084 132.206 136.195 1.00 20.80  ? 84  SER B CB  1 
ATOM   3777 O  OG  . SER B 1 84  ? 129.777 133.390 136.520 1.00 35.43  ? 84  SER B OG  1 
ATOM   3778 N  N   . VAL B 1 85  ? 131.660 132.529 134.176 1.00 17.94  ? 85  VAL B N   1 
ATOM   3779 C  CA  . VAL B 1 85  ? 132.228 133.104 132.961 1.00 20.77  ? 85  VAL B CA  1 
ATOM   3780 C  C   . VAL B 1 85  ? 132.592 132.011 131.965 1.00 30.39  ? 85  VAL B C   1 
ATOM   3781 O  O   . VAL B 1 85  ? 132.459 132.197 130.750 1.00 37.87  ? 85  VAL B O   1 
ATOM   3782 C  CB  . VAL B 1 85  ? 133.439 133.985 133.312 1.00 18.49  ? 85  VAL B CB  1 
ATOM   3783 C  CG1 . VAL B 1 85  ? 134.197 134.371 132.073 1.00 29.92  ? 85  VAL B CG1 1 
ATOM   3784 C  CG2 . VAL B 1 85  ? 132.983 135.220 134.033 1.00 21.69  ? 85  VAL B CG2 1 
ATOM   3785 N  N   . LEU B 1 86  ? 133.043 130.857 132.449 1.00 25.32  ? 86  LEU B N   1 
ATOM   3786 C  CA  . LEU B 1 86  ? 133.445 129.771 131.570 1.00 25.61  ? 86  LEU B CA  1 
ATOM   3787 C  C   . LEU B 1 86  ? 132.300 128.854 131.166 1.00 24.58  ? 86  LEU B C   1 
ATOM   3788 O  O   . LEU B 1 86  ? 132.438 128.126 130.179 1.00 35.54  ? 86  LEU B O   1 
ATOM   3789 C  CB  . LEU B 1 86  ? 134.526 128.918 132.235 1.00 27.46  ? 86  LEU B CB  1 
ATOM   3790 C  CG  . LEU B 1 86  ? 135.601 129.589 133.078 1.00 20.98  ? 86  LEU B CG  1 
ATOM   3791 C  CD1 . LEU B 1 86  ? 136.231 128.555 133.967 1.00 27.25  ? 86  LEU B CD1 1 
ATOM   3792 C  CD2 . LEU B 1 86  ? 136.644 130.225 132.203 1.00 22.26  ? 86  LEU B CD2 1 
ATOM   3793 N  N   . ALA B 1 87  ? 131.182 128.859 131.889 1.00 25.00  ? 87  ALA B N   1 
ATOM   3794 C  CA  . ALA B 1 87  ? 130.181 127.824 131.684 1.00 27.95  ? 87  ALA B CA  1 
ATOM   3795 C  C   . ALA B 1 87  ? 128.735 128.298 131.651 1.00 29.17  ? 87  ALA B C   1 
ATOM   3796 O  O   . ALA B 1 87  ? 127.849 127.461 131.461 1.00 34.17  ? 87  ALA B O   1 
ATOM   3797 C  CB  . ALA B 1 87  ? 130.319 126.746 132.767 1.00 26.83  ? 87  ALA B CB  1 
ATOM   3798 N  N   . PHE B 1 88  ? 128.454 129.583 131.815 1.00 20.64  ? 88  PHE B N   1 
ATOM   3799 C  CA  . PHE B 1 88  ? 127.042 129.928 131.879 1.00 18.63  ? 88  PHE B CA  1 
ATOM   3800 C  C   . PHE B 1 88  ? 126.629 130.800 130.697 1.00 30.93  ? 88  PHE B C   1 
ATOM   3801 O  O   . PHE B 1 88  ? 127.448 131.541 130.150 1.00 41.51  ? 88  PHE B O   1 
ATOM   3802 C  CB  . PHE B 1 88  ? 126.713 130.654 133.188 1.00 19.27  ? 88  PHE B CB  1 
ATOM   3803 C  CG  . PHE B 1 88  ? 126.306 129.733 134.301 1.00 19.82  ? 88  PHE B CG  1 
ATOM   3804 C  CD1 . PHE B 1 88  ? 125.625 128.565 134.030 1.00 24.67  ? 88  PHE B CD1 1 
ATOM   3805 C  CD2 . PHE B 1 88  ? 126.600 130.034 135.611 1.00 22.97  ? 88  PHE B CD2 1 
ATOM   3806 C  CE1 . PHE B 1 88  ? 125.252 127.721 135.046 1.00 28.84  ? 88  PHE B CE1 1 
ATOM   3807 C  CE2 . PHE B 1 88  ? 126.229 129.192 136.628 1.00 25.04  ? 88  PHE B CE2 1 
ATOM   3808 C  CZ  . PHE B 1 88  ? 125.553 128.037 136.345 1.00 25.04  ? 88  PHE B CZ  1 
ATOM   3809 N  N   . PRO B 1 89  ? 125.369 130.719 130.267 1.00 19.10  ? 89  PRO B N   1 
ATOM   3810 C  CA  . PRO B 1 89  ? 124.922 131.525 129.129 1.00 11.77  ? 89  PRO B CA  1 
ATOM   3811 C  C   . PRO B 1 89  ? 124.790 132.995 129.487 1.00 22.16  ? 89  PRO B C   1 
ATOM   3812 O  O   . PRO B 1 89  ? 124.491 133.358 130.625 1.00 33.90  ? 89  PRO B O   1 
ATOM   3813 C  CB  . PRO B 1 89  ? 123.560 130.918 128.789 1.00 21.46  ? 89  PRO B CB  1 
ATOM   3814 C  CG  . PRO B 1 89  ? 123.093 130.353 130.061 1.00 16.90  ? 89  PRO B CG  1 
ATOM   3815 C  CD  . PRO B 1 89  ? 124.310 129.813 130.734 1.00 21.27  ? 89  PRO B CD  1 
ATOM   3816 N  N   . ASN B 1 90  ? 124.986 133.849 128.482 1.00 18.20  ? 90  ASN B N   1 
ATOM   3817 C  CA  . ASN B 1 90  ? 125.050 135.287 128.692 1.00 13.67  ? 90  ASN B CA  1 
ATOM   3818 C  C   . ASN B 1 90  ? 123.791 136.018 128.242 1.00 24.99  ? 90  ASN B C   1 
ATOM   3819 O  O   . ASN B 1 90  ? 123.831 137.237 128.056 1.00 41.34  ? 90  ASN B O   1 
ATOM   3820 C  CB  . ASN B 1 90  ? 126.275 135.871 127.990 1.00 25.45  ? 90  ASN B CB  1 
ATOM   3821 C  CG  . ASN B 1 90  ? 126.151 135.858 126.490 1.00 27.50  ? 90  ASN B CG  1 
ATOM   3822 O  OD1 . ASN B 1 90  ? 125.633 136.793 125.890 1.00 27.21  ? 90  ASN B OD1 1 
ATOM   3823 N  ND2 . ASN B 1 90  ? 126.643 134.797 125.869 1.00 29.64  ? 90  ASN B ND2 1 
ATOM   3824 N  N   . GLY B 1 91  ? 122.679 135.312 128.072 1.00 26.02  ? 91  GLY B N   1 
ATOM   3825 C  CA  . GLY B 1 91  ? 121.429 135.949 127.730 1.00 25.66  ? 91  GLY B CA  1 
ATOM   3826 C  C   . GLY B 1 91  ? 121.432 136.465 126.310 1.00 18.99  ? 91  GLY B C   1 
ATOM   3827 O  O   . GLY B 1 91  ? 122.297 136.119 125.504 1.00 25.60  ? 91  GLY B O   1 
ATOM   3828 N  N   . PRO B 1 92  ? 120.456 137.303 125.969 1.00 14.64  ? 92  PRO B N   1 
ATOM   3829 C  CA  . PRO B 1 92  ? 120.449 137.958 124.657 1.00 26.21  ? 92  PRO B CA  1 
ATOM   3830 C  C   . PRO B 1 92  ? 121.269 139.237 124.592 1.00 35.12  ? 92  PRO B C   1 
ATOM   3831 O  O   . PRO B 1 92  ? 121.162 139.968 123.604 1.00 42.33  ? 92  PRO B O   1 
ATOM   3832 C  CB  . PRO B 1 92  ? 118.962 138.266 124.461 1.00 25.02  ? 92  PRO B CB  1 
ATOM   3833 C  CG  . PRO B 1 92  ? 118.465 138.520 125.828 1.00 22.71  ? 92  PRO B CG  1 
ATOM   3834 C  CD  . PRO B 1 92  ? 119.300 137.708 126.783 1.00 22.18  ? 92  PRO B CD  1 
ATOM   3835 N  N   . PHE B 1 93  ? 122.073 139.514 125.611 1.00 26.64  ? 93  PHE B N   1 
ATOM   3836 C  CA  . PHE B 1 93  ? 122.824 140.752 125.719 1.00 25.48  ? 93  PHE B CA  1 
ATOM   3837 C  C   . PHE B 1 93  ? 124.305 140.474 125.533 1.00 33.82  ? 93  PHE B C   1 
ATOM   3838 O  O   . PHE B 1 93  ? 124.826 139.473 126.028 1.00 35.68  ? 93  PHE B O   1 
ATOM   3839 C  CB  . PHE B 1 93  ? 122.596 141.409 127.076 1.00 24.52  ? 93  PHE B CB  1 
ATOM   3840 C  CG  . PHE B 1 93  ? 121.217 141.948 127.264 1.00 19.49  ? 93  PHE B CG  1 
ATOM   3841 C  CD1 . PHE B 1 93  ? 120.323 141.979 126.220 1.00 28.45  ? 93  PHE B CD1 1 
ATOM   3842 C  CD2 . PHE B 1 93  ? 120.820 142.427 128.485 1.00 27.77  ? 93  PHE B CD2 1 
ATOM   3843 C  CE1 . PHE B 1 93  ? 119.063 142.470 126.394 1.00 24.88  ? 93  PHE B CE1 1 
ATOM   3844 C  CE2 . PHE B 1 93  ? 119.562 142.921 128.660 1.00 31.10  ? 93  PHE B CE2 1 
ATOM   3845 C  CZ  . PHE B 1 93  ? 118.682 142.943 127.614 1.00 29.08  ? 93  PHE B CZ  1 
ATOM   3846 N  N   . THR B 1 94  ? 124.980 141.372 124.824 1.00 38.98  ? 94  THR B N   1 
ATOM   3847 C  CA  . THR B 1 94  ? 126.393 141.200 124.532 1.00 28.69  ? 94  THR B CA  1 
ATOM   3848 C  C   . THR B 1 94  ? 127.159 142.500 124.717 1.00 31.70  ? 94  THR B C   1 
ATOM   3849 O  O   . THR B 1 94  ? 128.199 142.705 124.085 1.00 44.30  ? 94  THR B O   1 
ATOM   3850 C  CB  . THR B 1 94  ? 126.593 140.661 123.117 1.00 32.65  ? 94  THR B CB  1 
ATOM   3851 O  OG1 . THR B 1 94  ? 127.989 140.476 122.873 1.00 49.26  ? 94  THR B OG1 1 
ATOM   3852 C  CG2 . THR B 1 94  ? 126.020 141.618 122.088 1.00 33.76  ? 94  THR B CG2 1 
ATOM   3853 N  N   . ARG B 1 95  ? 126.663 143.384 125.575 1.00 28.96  ? 95  ARG B N   1 
ATOM   3854 C  CA  . ARG B 1 95  ? 127.319 144.644 125.882 1.00 30.30  ? 95  ARG B CA  1 
ATOM   3855 C  C   . ARG B 1 95  ? 127.143 144.955 127.360 1.00 37.99  ? 95  ARG B C   1 
ATOM   3856 O  O   . ARG B 1 95  ? 126.106 144.623 127.944 1.00 42.61  ? 95  ARG B O   1 
ATOM   3857 C  CB  . ARG B 1 95  ? 126.750 145.797 125.043 1.00 29.83  ? 95  ARG B CB  1 
ATOM   3858 C  CG  . ARG B 1 95  ? 127.367 145.913 123.674 1.00 35.39  ? 95  ARG B CG  1 
ATOM   3859 C  CD  . ARG B 1 95  ? 127.650 147.350 123.331 1.00 34.68  ? 95  ARG B CD  1 
ATOM   3860 N  NE  . ARG B 1 95  ? 128.509 147.469 122.163 1.00 33.14  ? 95  ARG B NE  1 
ATOM   3861 C  CZ  . ARG B 1 95  ? 128.551 148.530 121.372 1.00 38.40  ? 95  ARG B CZ  1 
ATOM   3862 N  NH1 . ARG B 1 95  ? 127.790 149.586 121.594 1.00 40.67  ? 95  ARG B NH1 1 
ATOM   3863 N  NH2 . ARG B 1 95  ? 129.379 148.531 120.334 1.00 46.10  ? 95  ARG B NH2 1 
ATOM   3864 N  N   . PRO B 1 96  ? 128.139 145.587 127.995 1.00 36.22  ? 96  PRO B N   1 
ATOM   3865 C  CA  . PRO B 1 96  ? 129.456 145.984 127.474 1.00 34.08  ? 96  PRO B CA  1 
ATOM   3866 C  C   . PRO B 1 96  ? 130.334 144.786 127.139 1.00 42.43  ? 96  PRO B C   1 
ATOM   3867 O  O   . PRO B 1 96  ? 131.105 144.814 126.186 1.00 47.21  ? 96  PRO B O   1 
ATOM   3868 C  CB  . PRO B 1 96  ? 130.044 146.813 128.622 1.00 31.78  ? 96  PRO B CB  1 
ATOM   3869 C  CG  . PRO B 1 96  ? 129.347 146.329 129.842 1.00 35.18  ? 96  PRO B CG  1 
ATOM   3870 C  CD  . PRO B 1 96  ? 127.958 146.009 129.392 1.00 32.43  ? 96  PRO B CD  1 
ATOM   3871 N  N   . HIS B 1 97  ? 130.228 143.714 127.913 1.00 37.94  ? 97  HIS B N   1 
ATOM   3872 C  CA  . HIS B 1 97  ? 130.873 142.450 127.610 1.00 35.01  ? 97  HIS B CA  1 
ATOM   3873 C  C   . HIS B 1 97  ? 129.901 141.328 127.926 1.00 32.35  ? 97  HIS B C   1 
ATOM   3874 O  O   . HIS B 1 97  ? 129.110 141.442 128.867 1.00 38.96  ? 97  HIS B O   1 
ATOM   3875 C  CB  . HIS B 1 97  ? 132.166 142.261 128.415 1.00 40.02  ? 97  HIS B CB  1 
ATOM   3876 C  CG  . HIS B 1 97  ? 133.144 141.331 127.772 1.00 38.43  ? 97  HIS B CG  1 
ATOM   3877 N  ND1 . HIS B 1 97  ? 133.211 139.993 128.085 1.00 36.64  ? 97  HIS B ND1 1 
ATOM   3878 C  CD2 . HIS B 1 97  ? 134.095 141.546 126.835 1.00 34.94  ? 97  HIS B CD2 1 
ATOM   3879 C  CE1 . HIS B 1 97  ? 134.158 139.421 127.366 1.00 33.07  ? 97  HIS B CE1 1 
ATOM   3880 N  NE2 . HIS B 1 97  ? 134.711 140.342 126.600 1.00 33.78  ? 97  HIS B NE2 1 
ATOM   3881 N  N   . PRO B 1 98  ? 129.923 140.243 127.152 1.00 26.51  ? 98  PRO B N   1 
ATOM   3882 C  CA  . PRO B 1 98  ? 129.065 139.101 127.486 1.00 21.77  ? 98  PRO B CA  1 
ATOM   3883 C  C   . PRO B 1 98  ? 129.363 138.501 128.843 1.00 25.80  ? 98  PRO B C   1 
ATOM   3884 O  O   . PRO B 1 98  ? 128.454 137.961 129.480 1.00 36.70  ? 98  PRO B O   1 
ATOM   3885 C  CB  . PRO B 1 98  ? 129.356 138.111 126.354 1.00 29.09  ? 98  PRO B CB  1 
ATOM   3886 C  CG  . PRO B 1 98  ? 129.831 138.949 125.238 1.00 27.48  ? 98  PRO B CG  1 
ATOM   3887 C  CD  . PRO B 1 98  ? 130.615 140.047 125.870 1.00 31.63  ? 98  PRO B CD  1 
ATOM   3888 N  N   . ALA B 1 99  ? 130.611 138.581 129.310 1.00 29.03  ? 99  ALA B N   1 
ATOM   3889 C  CA  . ALA B 1 99  ? 130.983 137.936 130.563 1.00 26.81  ? 99  ALA B CA  1 
ATOM   3890 C  C   . ALA B 1 99  ? 130.335 138.601 131.767 1.00 29.96  ? 99  ALA B C   1 
ATOM   3891 O  O   . ALA B 1 99  ? 130.141 137.948 132.795 1.00 42.84  ? 99  ALA B O   1 
ATOM   3892 C  CB  . ALA B 1 99  ? 132.498 137.933 130.724 1.00 30.88  ? 99  ALA B CB  1 
ATOM   3893 N  N   . LEU B 1 100 ? 130.005 139.888 131.673 1.00 25.30  ? 100 LEU B N   1 
ATOM   3894 C  CA  . LEU B 1 100 ? 129.303 140.550 132.766 1.00 22.81  ? 100 LEU B CA  1 
ATOM   3895 C  C   . LEU B 1 100 ? 127.861 140.093 132.890 1.00 23.96  ? 100 LEU B C   1 
ATOM   3896 O  O   . LEU B 1 100 ? 127.223 140.389 133.904 1.00 35.56  ? 100 LEU B O   1 
ATOM   3897 C  CB  . LEU B 1 100 ? 129.350 142.070 132.597 1.00 24.76  ? 100 LEU B CB  1 
ATOM   3898 C  CG  . LEU B 1 100 ? 130.595 142.837 133.066 1.00 40.44  ? 100 LEU B CG  1 
ATOM   3899 C  CD1 . LEU B 1 100 ? 131.891 142.072 132.872 1.00 41.37  ? 100 LEU B CD1 1 
ATOM   3900 C  CD2 . LEU B 1 100 ? 130.684 144.181 132.377 1.00 38.17  ? 100 LEU B CD2 1 
ATOM   3901 N  N   . TRP B 1 101 ? 127.333 139.392 131.888 1.00 22.18  ? 101 TRP B N   1 
ATOM   3902 C  CA  . TRP B 1 101 ? 125.997 138.823 131.950 1.00 15.32  ? 101 TRP B CA  1 
ATOM   3903 C  C   . TRP B 1 101 ? 126.005 137.338 132.268 1.00 26.49  ? 101 TRP B C   1 
ATOM   3904 O  O   . TRP B 1 101 ? 124.971 136.805 132.681 1.00 36.13  ? 101 TRP B O   1 
ATOM   3905 C  CB  . TRP B 1 101 ? 125.258 139.068 130.632 1.00 17.86  ? 101 TRP B CB  1 
ATOM   3906 C  CG  . TRP B 1 101 ? 125.040 140.517 130.366 1.00 23.80  ? 101 TRP B CG  1 
ATOM   3907 C  CD1 . TRP B 1 101 ? 125.739 141.305 129.509 1.00 19.31  ? 101 TRP B CD1 1 
ATOM   3908 C  CD2 . TRP B 1 101 ? 124.067 141.362 130.985 1.00 30.07  ? 101 TRP B CD2 1 
ATOM   3909 N  NE1 . TRP B 1 101 ? 125.259 142.587 129.546 1.00 21.86  ? 101 TRP B NE1 1 
ATOM   3910 C  CE2 . TRP B 1 101 ? 124.229 142.647 130.446 1.00 28.32  ? 101 TRP B CE2 1 
ATOM   3911 C  CE3 . TRP B 1 101 ? 123.070 141.155 131.941 1.00 31.74  ? 101 TRP B CE3 1 
ATOM   3912 C  CZ2 . TRP B 1 101 ? 123.434 143.719 130.830 1.00 30.05  ? 101 TRP B CZ2 1 
ATOM   3913 C  CZ3 . TRP B 1 101 ? 122.283 142.218 132.319 1.00 23.47  ? 101 TRP B CZ3 1 
ATOM   3914 C  CH2 . TRP B 1 101 ? 122.468 143.484 131.767 1.00 25.45  ? 101 TRP B CH2 1 
ATOM   3915 N  N   . ARG B 1 102 ? 127.137 136.660 132.074 1.00 23.41  ? 102 ARG B N   1 
ATOM   3916 C  CA  . ARG B 1 102 ? 127.319 135.338 132.658 1.00 9.24   ? 102 ARG B CA  1 
ATOM   3917 C  C   . ARG B 1 102 ? 127.516 135.429 134.162 1.00 22.29  ? 102 ARG B C   1 
ATOM   3918 O  O   . ARG B 1 102 ? 127.135 134.511 134.893 1.00 33.74  ? 102 ARG B O   1 
ATOM   3919 C  CB  . ARG B 1 102 ? 128.513 134.639 132.022 1.00 15.64  ? 102 ARG B CB  1 
ATOM   3920 C  CG  . ARG B 1 102 ? 128.478 134.587 130.522 1.00 18.47  ? 102 ARG B CG  1 
ATOM   3921 C  CD  . ARG B 1 102 ? 129.664 133.828 129.978 1.00 19.64  ? 102 ARG B CD  1 
ATOM   3922 N  NE  . ARG B 1 102 ? 129.764 133.959 128.533 1.00 19.64  ? 102 ARG B NE  1 
ATOM   3923 C  CZ  . ARG B 1 102 ? 130.775 134.540 127.907 1.00 30.58  ? 102 ARG B CZ  1 
ATOM   3924 N  NH1 . ARG B 1 102 ? 131.803 135.040 128.570 1.00 30.83  ? 102 ARG B NH1 1 
ATOM   3925 N  NH2 . ARG B 1 102 ? 130.754 134.624 126.581 1.00 31.52  ? 102 ARG B NH2 1 
ATOM   3926 N  N   . MET B 1 103 ? 128.120 136.516 134.638 1.00 25.21  ? 103 MET B N   1 
ATOM   3927 C  CA  . MET B 1 103 ? 128.292 136.742 136.065 1.00 16.99  ? 103 MET B CA  1 
ATOM   3928 C  C   . MET B 1 103 ? 127.022 137.235 136.737 1.00 23.99  ? 103 MET B C   1 
ATOM   3929 O  O   . MET B 1 103 ? 126.908 137.134 137.960 1.00 41.96  ? 103 MET B O   1 
ATOM   3930 C  CB  . MET B 1 103 ? 129.421 137.743 136.296 1.00 18.76  ? 103 MET B CB  1 
ATOM   3931 C  CG  . MET B 1 103 ? 130.797 137.155 136.095 1.00 28.27  ? 103 MET B CG  1 
ATOM   3932 S  SD  . MET B 1 103 ? 132.109 138.382 136.085 1.00 46.78  ? 103 MET B SD  1 
ATOM   3933 C  CE  . MET B 1 103 ? 131.402 139.637 137.135 1.00 30.71  ? 103 MET B CE  1 
ATOM   3934 N  N   . VAL B 1 104 ? 126.077 137.780 135.974 1.00 21.76  ? 104 VAL B N   1 
ATOM   3935 C  CA  . VAL B 1 104 ? 124.764 138.100 136.519 1.00 13.36  ? 104 VAL B CA  1 
ATOM   3936 C  C   . VAL B 1 104 ? 123.895 136.853 136.565 1.00 19.84  ? 104 VAL B C   1 
ATOM   3937 O  O   . VAL B 1 104 ? 123.117 136.659 137.502 1.00 38.60  ? 104 VAL B O   1 
ATOM   3938 C  CB  . VAL B 1 104 ? 124.110 139.228 135.701 1.00 23.18  ? 104 VAL B CB  1 
ATOM   3939 C  CG1 . VAL B 1 104 ? 122.619 139.260 135.925 1.00 22.78  ? 104 VAL B CG1 1 
ATOM   3940 C  CG2 . VAL B 1 104 ? 124.724 140.563 136.063 1.00 23.95  ? 104 VAL B CG2 1 
ATOM   3941 N  N   . PHE B 1 105 ? 124.016 135.984 135.560 1.00 29.86  ? 105 PHE B N   1 
ATOM   3942 C  CA  . PHE B 1 105 ? 123.355 134.687 135.623 1.00 21.05  ? 105 PHE B CA  1 
ATOM   3943 C  C   . PHE B 1 105 ? 123.957 133.808 136.708 1.00 21.08  ? 105 PHE B C   1 
ATOM   3944 O  O   . PHE B 1 105 ? 123.267 132.946 137.259 1.00 28.15  ? 105 PHE B O   1 
ATOM   3945 C  CB  . PHE B 1 105 ? 123.435 133.985 134.269 1.00 18.69  ? 105 PHE B CB  1 
ATOM   3946 C  CG  . PHE B 1 105 ? 122.698 132.683 134.220 1.00 22.30  ? 105 PHE B CG  1 
ATOM   3947 C  CD1 . PHE B 1 105 ? 121.338 132.653 134.025 1.00 24.38  ? 105 PHE B CD1 1 
ATOM   3948 C  CD2 . PHE B 1 105 ? 123.364 131.490 134.376 1.00 26.73  ? 105 PHE B CD2 1 
ATOM   3949 C  CE1 . PHE B 1 105 ? 120.664 131.461 133.986 1.00 23.34  ? 105 PHE B CE1 1 
ATOM   3950 C  CE2 . PHE B 1 105 ? 122.687 130.297 134.338 1.00 14.43  ? 105 PHE B CE2 1 
ATOM   3951 C  CZ  . PHE B 1 105 ? 121.341 130.286 134.145 1.00 13.42  ? 105 PHE B CZ  1 
ATOM   3952 N  N   . GLY B 1 106 ? 125.238 133.999 137.020 1.00 24.83  ? 106 GLY B N   1 
ATOM   3953 C  CA  . GLY B 1 106 ? 125.841 133.250 138.108 1.00 18.54  ? 106 GLY B CA  1 
ATOM   3954 C  C   . GLY B 1 106 ? 125.255 133.614 139.456 1.00 25.97  ? 106 GLY B C   1 
ATOM   3955 O  O   . GLY B 1 106 ? 125.129 132.760 140.335 1.00 40.50  ? 106 GLY B O   1 
ATOM   3956 N  N   . LEU B 1 107 ? 124.899 134.885 139.644 1.00 20.19  ? 107 LEU B N   1 
ATOM   3957 C  CA  . LEU B 1 107 ? 124.261 135.312 140.883 1.00 15.38  ? 107 LEU B CA  1 
ATOM   3958 C  C   . LEU B 1 107 ? 122.797 134.900 140.946 1.00 24.20  ? 107 LEU B C   1 
ATOM   3959 O  O   . LEU B 1 107 ? 122.260 134.719 142.041 1.00 36.17  ? 107 LEU B O   1 
ATOM   3960 C  CB  . LEU B 1 107 ? 124.376 136.825 141.046 1.00 22.13  ? 107 LEU B CB  1 
ATOM   3961 C  CG  . LEU B 1 107 ? 125.773 137.429 141.152 1.00 21.15  ? 107 LEU B CG  1 
ATOM   3962 C  CD1 . LEU B 1 107 ? 125.681 138.934 141.169 1.00 23.25  ? 107 LEU B CD1 1 
ATOM   3963 C  CD2 . LEU B 1 107 ? 126.478 136.931 142.391 1.00 27.87  ? 107 LEU B CD2 1 
ATOM   3964 N  N   . SER B 1 108 ? 122.135 134.767 139.795 1.00 23.19  ? 108 SER B N   1 
ATOM   3965 C  CA  . SER B 1 108 ? 120.760 134.279 139.783 1.00 15.88  ? 108 SER B CA  1 
ATOM   3966 C  C   . SER B 1 108 ? 120.676 132.859 140.315 1.00 31.47  ? 108 SER B C   1 
ATOM   3967 O  O   . SER B 1 108 ? 119.774 132.530 141.092 1.00 40.37  ? 108 SER B O   1 
ATOM   3968 C  CB  . SER B 1 108 ? 120.197 134.337 138.367 1.00 14.85  ? 108 SER B CB  1 
ATOM   3969 O  OG  . SER B 1 108 ? 120.565 135.537 137.723 1.00 38.49  ? 108 SER B OG  1 
ATOM   3970 N  N   . VAL B 1 109 ? 121.602 131.997 139.894 1.00 28.72  ? 109 VAL B N   1 
ATOM   3971 C  CA  . VAL B 1 109 ? 121.606 130.616 140.358 1.00 13.21  ? 109 VAL B CA  1 
ATOM   3972 C  C   . VAL B 1 109 ? 121.974 130.548 141.834 1.00 19.27  ? 109 VAL B C   1 
ATOM   3973 O  O   . VAL B 1 109 ? 121.445 129.718 142.579 1.00 30.77  ? 109 VAL B O   1 
ATOM   3974 C  CB  . VAL B 1 109 ? 122.552 129.770 139.490 1.00 16.42  ? 109 VAL B CB  1 
ATOM   3975 C  CG1 . VAL B 1 109 ? 122.641 128.360 140.021 1.00 29.06  ? 109 VAL B CG1 1 
ATOM   3976 C  CG2 . VAL B 1 109 ? 122.073 129.765 138.058 1.00 21.85  ? 109 VAL B CG2 1 
ATOM   3977 N  N   . LEU B 1 110 ? 122.888 131.411 142.281 1.00 25.74  ? 110 LEU B N   1 
ATOM   3978 C  CA  . LEU B 1 110 ? 123.209 131.467 143.704 1.00 21.29  ? 110 LEU B CA  1 
ATOM   3979 C  C   . LEU B 1 110 ? 121.987 131.849 144.525 1.00 32.87  ? 110 LEU B C   1 
ATOM   3980 O  O   . LEU B 1 110 ? 121.712 131.241 145.564 1.00 38.28  ? 110 LEU B O   1 
ATOM   3981 C  CB  . LEU B 1 110 ? 124.334 132.465 143.955 1.00 22.68  ? 110 LEU B CB  1 
ATOM   3982 C  CG  . LEU B 1 110 ? 125.770 132.030 143.693 1.00 25.08  ? 110 LEU B CG  1 
ATOM   3983 C  CD1 . LEU B 1 110 ? 126.716 133.175 143.971 1.00 26.75  ? 110 LEU B CD1 1 
ATOM   3984 C  CD2 . LEU B 1 110 ? 126.124 130.836 144.536 1.00 35.09  ? 110 LEU B CD2 1 
ATOM   3985 N  N   . TYR B 1 111 ? 121.237 132.854 144.071 1.00 31.02  ? 111 TYR B N   1 
ATOM   3986 C  CA  . TYR B 1 111 ? 120.060 133.290 144.809 1.00 22.52  ? 111 TYR B CA  1 
ATOM   3987 C  C   . TYR B 1 111 ? 118.918 132.293 144.694 1.00 27.41  ? 111 TYR B C   1 
ATOM   3988 O  O   . TYR B 1 111 ? 118.117 132.167 145.623 1.00 40.68  ? 111 TYR B O   1 
ATOM   3989 C  CB  . TYR B 1 111 ? 119.612 134.661 144.320 1.00 17.93  ? 111 TYR B CB  1 
ATOM   3990 C  CG  . TYR B 1 111 ? 118.485 135.244 145.125 1.00 32.64  ? 111 TYR B CG  1 
ATOM   3991 C  CD1 . TYR B 1 111 ? 118.538 135.270 146.506 1.00 35.03  ? 111 TYR B CD1 1 
ATOM   3992 C  CD2 . TYR B 1 111 ? 117.367 135.771 144.506 1.00 41.31  ? 111 TYR B CD2 1 
ATOM   3993 C  CE1 . TYR B 1 111 ? 117.511 135.805 147.246 1.00 32.16  ? 111 TYR B CE1 1 
ATOM   3994 C  CE2 . TYR B 1 111 ? 116.335 136.305 145.237 1.00 33.38  ? 111 TYR B CE2 1 
ATOM   3995 C  CZ  . TYR B 1 111 ? 116.412 136.321 146.605 1.00 33.02  ? 111 TYR B CZ  1 
ATOM   3996 O  OH  . TYR B 1 111 ? 115.381 136.856 147.337 1.00 37.16  ? 111 TYR B OH  1 
ATOM   3997 N  N   . PHE B 1 112 ? 118.811 131.592 143.566 1.00 28.31  ? 112 PHE B N   1 
ATOM   3998 C  CA  . PHE B 1 112 ? 117.788 130.561 143.442 1.00 22.08  ? 112 PHE B CA  1 
ATOM   3999 C  C   . PHE B 1 112 ? 118.024 129.437 144.440 1.00 25.64  ? 112 PHE B C   1 
ATOM   4000 O  O   . PHE B 1 112 ? 117.089 128.990 145.110 1.00 29.19  ? 112 PHE B O   1 
ATOM   4001 C  CB  . PHE B 1 112 ? 117.760 130.031 142.007 1.00 19.91  ? 112 PHE B CB  1 
ATOM   4002 C  CG  . PHE B 1 112 ? 117.159 128.662 141.864 1.00 22.14  ? 112 PHE B CG  1 
ATOM   4003 C  CD1 . PHE B 1 112 ? 115.882 128.389 142.317 1.00 32.01  ? 112 PHE B CD1 1 
ATOM   4004 C  CD2 . PHE B 1 112 ? 117.871 127.650 141.254 1.00 24.60  ? 112 PHE B CD2 1 
ATOM   4005 C  CE1 . PHE B 1 112 ? 115.339 127.129 142.180 1.00 26.81  ? 112 PHE B CE1 1 
ATOM   4006 C  CE2 . PHE B 1 112 ? 117.330 126.395 141.114 1.00 26.88  ? 112 PHE B CE2 1 
ATOM   4007 C  CZ  . PHE B 1 112 ? 116.063 126.135 141.575 1.00 26.78  ? 112 PHE B CZ  1 
ATOM   4008 N  N   . LEU B 1 113 ? 119.272 128.983 144.572 1.00 32.17  ? 113 LEU B N   1 
ATOM   4009 C  CA  . LEU B 1 113 ? 119.567 127.879 145.480 1.00 23.91  ? 113 LEU B CA  1 
ATOM   4010 C  C   . LEU B 1 113 ? 119.539 128.319 146.934 1.00 31.80  ? 113 LEU B C   1 
ATOM   4011 O  O   . LEU B 1 113 ? 119.299 127.495 147.821 1.00 42.88  ? 113 LEU B O   1 
ATOM   4012 C  CB  . LEU B 1 113 ? 120.922 127.270 145.143 1.00 18.98  ? 113 LEU B CB  1 
ATOM   4013 C  CG  . LEU B 1 113 ? 121.086 126.750 143.721 1.00 22.13  ? 113 LEU B CG  1 
ATOM   4014 C  CD1 . LEU B 1 113 ? 122.546 126.516 143.436 1.00 29.51  ? 113 LEU B CD1 1 
ATOM   4015 C  CD2 . LEU B 1 113 ? 120.288 125.486 143.537 1.00 27.84  ? 113 LEU B CD2 1 
ATOM   4016 N  N   . PHE B 1 114 ? 119.797 129.598 147.204 1.00 32.58  ? 114 PHE B N   1 
ATOM   4017 C  CA  . PHE B 1 114 ? 119.653 130.106 148.563 1.00 25.90  ? 114 PHE B CA  1 
ATOM   4018 C  C   . PHE B 1 114 ? 118.210 130.002 149.031 1.00 32.67  ? 114 PHE B C   1 
ATOM   4019 O  O   . PHE B 1 114 ? 117.947 129.639 150.181 1.00 42.08  ? 114 PHE B O   1 
ATOM   4020 C  CB  . PHE B 1 114 ? 120.140 131.550 148.637 1.00 24.43  ? 114 PHE B CB  1 
ATOM   4021 C  CG  . PHE B 1 114 ? 119.963 132.182 149.981 1.00 34.31  ? 114 PHE B CG  1 
ATOM   4022 C  CD1 . PHE B 1 114 ? 120.502 131.600 151.110 1.00 35.15  ? 114 PHE B CD1 1 
ATOM   4023 C  CD2 . PHE B 1 114 ? 119.265 133.364 150.116 1.00 34.34  ? 114 PHE B CD2 1 
ATOM   4024 C  CE1 . PHE B 1 114 ? 120.345 132.182 152.347 1.00 28.67  ? 114 PHE B CE1 1 
ATOM   4025 C  CE2 . PHE B 1 114 ? 119.105 133.949 151.352 1.00 36.66  ? 114 PHE B CE2 1 
ATOM   4026 C  CZ  . PHE B 1 114 ? 119.647 133.356 152.467 1.00 30.36  ? 114 PHE B CZ  1 
ATOM   4027 N  N   . LEU B 1 115 ? 117.259 130.314 148.150 1.00 33.06  ? 115 LEU B N   1 
ATOM   4028 C  CA  . LEU B 1 115 ? 115.849 130.205 148.505 1.00 29.22  ? 115 LEU B CA  1 
ATOM   4029 C  C   . LEU B 1 115 ? 115.419 128.756 148.675 1.00 26.66  ? 115 LEU B C   1 
ATOM   4030 O  O   . LEU B 1 115 ? 114.539 128.468 149.490 1.00 36.82  ? 115 LEU B O   1 
ATOM   4031 C  CB  . LEU B 1 115 ? 114.987 130.885 147.446 1.00 31.74  ? 115 LEU B CB  1 
ATOM   4032 C  CG  . LEU B 1 115 ? 115.200 132.382 147.259 1.00 29.56  ? 115 LEU B CG  1 
ATOM   4033 C  CD1 . LEU B 1 115 ? 114.382 132.882 146.093 1.00 27.40  ? 115 LEU B CD1 1 
ATOM   4034 C  CD2 . LEU B 1 115 ? 114.841 133.122 148.529 1.00 32.22  ? 115 LEU B CD2 1 
ATOM   4035 N  N   . VAL B 1 116 ? 116.005 127.838 147.903 1.00 27.28  ? 116 VAL B N   1 
ATOM   4036 C  CA  . VAL B 1 116 ? 115.691 126.421 148.063 1.00 28.34  ? 116 VAL B CA  1 
ATOM   4037 C  C   . VAL B 1 116 ? 116.103 125.945 149.447 1.00 34.12  ? 116 VAL B C   1 
ATOM   4038 O  O   . VAL B 1 116 ? 115.408 125.140 150.079 1.00 38.10  ? 116 VAL B O   1 
ATOM   4039 C  CB  . VAL B 1 116 ? 116.368 125.595 146.955 1.00 29.86  ? 116 VAL B CB  1 
ATOM   4040 C  CG1 . VAL B 1 116 ? 116.050 124.138 147.124 1.00 32.33  ? 116 VAL B CG1 1 
ATOM   4041 C  CG2 . VAL B 1 116 ? 115.917 126.062 145.596 1.00 31.88  ? 116 VAL B CG2 1 
ATOM   4042 N  N   . PHE B 1 117 ? 117.246 126.426 149.935 1.00 38.77  ? 117 PHE B N   1 
ATOM   4043 C  CA  . PHE B 1 117 ? 117.682 126.098 151.286 1.00 35.60  ? 117 PHE B CA  1 
ATOM   4044 C  C   . PHE B 1 117 ? 116.727 126.661 152.330 1.00 32.15  ? 117 PHE B C   1 
ATOM   4045 O  O   . PHE B 1 117 ? 116.384 125.977 153.299 1.00 37.60  ? 117 PHE B O   1 
ATOM   4046 C  CB  . PHE B 1 117 ? 119.097 126.629 151.509 1.00 29.95  ? 117 PHE B CB  1 
ATOM   4047 C  CG  . PHE B 1 117 ? 119.707 126.206 152.806 1.00 31.07  ? 117 PHE B CG  1 
ATOM   4048 C  CD1 . PHE B 1 117 ? 119.987 124.880 153.052 1.00 33.54  ? 117 PHE B CD1 1 
ATOM   4049 C  CD2 . PHE B 1 117 ? 119.999 127.135 153.781 1.00 36.83  ? 117 PHE B CD2 1 
ATOM   4050 C  CE1 . PHE B 1 117 ? 120.544 124.490 154.242 1.00 35.81  ? 117 PHE B CE1 1 
ATOM   4051 C  CE2 . PHE B 1 117 ? 120.558 126.749 154.973 1.00 42.14  ? 117 PHE B CE2 1 
ATOM   4052 C  CZ  . PHE B 1 117 ? 120.830 125.425 155.203 1.00 37.52  ? 117 PHE B CZ  1 
ATOM   4053 N  N   . LEU B 1 118 ? 116.274 127.903 152.140 1.00 30.32  ? 118 LEU B N   1 
ATOM   4054 C  CA  . LEU B 1 118 ? 115.459 128.569 153.152 1.00 28.71  ? 118 LEU B CA  1 
ATOM   4055 C  C   . LEU B 1 118 ? 114.121 127.877 153.359 1.00 31.49  ? 118 LEU B C   1 
ATOM   4056 O  O   . LEU B 1 118 ? 113.568 127.920 154.462 1.00 39.11  ? 118 LEU B O   1 
ATOM   4057 C  CB  . LEU B 1 118 ? 115.229 130.029 152.768 1.00 24.20  ? 118 LEU B CB  1 
ATOM   4058 C  CG  . LEU B 1 118 ? 116.390 130.994 152.973 1.00 27.75  ? 118 LEU B CG  1 
ATOM   4059 C  CD1 . LEU B 1 118 ? 115.886 132.416 152.964 1.00 31.89  ? 118 LEU B CD1 1 
ATOM   4060 C  CD2 . LEU B 1 118 ? 117.105 130.693 154.267 1.00 38.68  ? 118 LEU B CD2 1 
ATOM   4061 N  N   . LEU B 1 119 ? 113.575 127.253 152.317 1.00 32.99  ? 119 LEU B N   1 
ATOM   4062 C  CA  . LEU B 1 119 ? 112.293 126.575 152.449 1.00 29.07  ? 119 LEU B CA  1 
ATOM   4063 C  C   . LEU B 1 119 ? 112.350 125.422 153.436 1.00 40.69  ? 119 LEU B C   1 
ATOM   4064 O  O   . LEU B 1 119 ? 111.315 125.045 153.992 1.00 46.88  ? 119 LEU B O   1 
ATOM   4065 C  CB  . LEU B 1 119 ? 111.830 126.061 151.088 1.00 23.82  ? 119 LEU B CB  1 
ATOM   4066 C  CG  . LEU B 1 119 ? 111.578 127.121 150.022 1.00 34.21  ? 119 LEU B CG  1 
ATOM   4067 C  CD1 . LEU B 1 119 ? 111.470 126.482 148.665 1.00 34.14  ? 119 LEU B CD1 1 
ATOM   4068 C  CD2 . LEU B 1 119 ? 110.317 127.874 150.347 1.00 37.30  ? 119 LEU B CD2 1 
ATOM   4069 N  N   . PHE B 1 120 ? 113.530 124.855 153.667 1.00 45.94  ? 120 PHE B N   1 
ATOM   4070 C  CA  . PHE B 1 120 ? 113.664 123.689 154.524 1.00 39.19  ? 120 PHE B CA  1 
ATOM   4071 C  C   . PHE B 1 120 ? 114.018 124.032 155.962 1.00 42.98  ? 120 PHE B C   1 
ATOM   4072 O  O   . PHE B 1 120 ? 113.940 123.152 156.823 1.00 52.16  ? 120 PHE B O   1 
ATOM   4073 C  CB  . PHE B 1 120 ? 114.712 122.740 153.945 1.00 32.74  ? 120 PHE B CB  1 
ATOM   4074 C  CG  . PHE B 1 120 ? 114.217 121.955 152.772 1.00 38.51  ? 120 PHE B CG  1 
ATOM   4075 C  CD1 . PHE B 1 120 ? 114.300 122.470 151.495 1.00 36.95  ? 120 PHE B CD1 1 
ATOM   4076 C  CD2 . PHE B 1 120 ? 113.651 120.709 152.948 1.00 42.05  ? 120 PHE B CD2 1 
ATOM   4077 C  CE1 . PHE B 1 120 ? 113.839 121.756 150.422 1.00 40.18  ? 120 PHE B CE1 1 
ATOM   4078 C  CE2 . PHE B 1 120 ? 113.188 119.993 151.878 1.00 40.84  ? 120 PHE B CE2 1 
ATOM   4079 C  CZ  . PHE B 1 120 ? 113.283 120.516 150.613 1.00 42.37  ? 120 PHE B CZ  1 
ATOM   4080 N  N   . LEU B 1 121 ? 114.390 125.274 156.246 1.00 35.18  ? 121 LEU B N   1 
ATOM   4081 C  CA  . LEU B 1 121 ? 114.649 125.701 157.613 1.00 33.22  ? 121 LEU B CA  1 
ATOM   4082 C  C   . LEU B 1 121 ? 113.321 126.027 158.289 1.00 36.43  ? 121 LEU B C   1 
ATOM   4083 O  O   . LEU B 1 121 ? 112.245 125.828 157.722 1.00 41.22  ? 121 LEU B O   1 
ATOM   4084 C  CB  . LEU B 1 121 ? 115.595 126.897 157.626 1.00 36.89  ? 121 LEU B CB  1 
ATOM   4085 C  CG  . LEU B 1 121 ? 116.920 126.817 156.871 1.00 30.58  ? 121 LEU B CG  1 
ATOM   4086 C  CD1 . LEU B 1 121 ? 117.770 128.023 157.196 1.00 34.95  ? 121 LEU B CD1 1 
ATOM   4087 C  CD2 . LEU B 1 121 ? 117.660 125.545 157.199 1.00 34.62  ? 121 LEU B CD2 1 
ATOM   4088 N  N   . ASN B 1 122 ? 113.379 126.527 159.516 1.00 44.46  ? 122 ASN B N   1 
ATOM   4089 C  CA  . ASN B 1 122 ? 112.226 127.109 160.187 1.00 43.65  ? 122 ASN B CA  1 
ATOM   4090 C  C   . ASN B 1 122 ? 112.508 128.583 160.452 1.00 51.40  ? 122 ASN B C   1 
ATOM   4091 O  O   . ASN B 1 122 ? 113.583 129.095 160.142 1.00 56.87  ? 122 ASN B O   1 
ATOM   4092 C  CB  . ASN B 1 122 ? 111.888 126.361 161.480 1.00 47.45  ? 122 ASN B CB  1 
ATOM   4093 C  CG  . ASN B 1 122 ? 113.109 126.031 162.303 1.00 53.27  ? 122 ASN B CG  1 
ATOM   4094 O  OD1 . ASN B 1 122 ? 114.236 126.226 161.862 1.00 57.56  ? 122 ASN B OD1 1 
ATOM   4095 N  ND2 . ASN B 1 122 ? 112.890 125.529 163.510 1.00 48.97  ? 122 ASN B ND2 1 
ATOM   4096 N  N   . PHE B 1 123 ? 111.523 129.273 161.025 1.00 55.92  ? 123 PHE B N   1 
ATOM   4097 C  CA  . PHE B 1 123 ? 111.645 130.716 161.189 1.00 55.68  ? 123 PHE B CA  1 
ATOM   4098 C  C   . PHE B 1 123 ? 112.732 131.089 162.185 1.00 57.44  ? 123 PHE B C   1 
ATOM   4099 O  O   . PHE B 1 123 ? 113.335 132.160 162.066 1.00 60.72  ? 123 PHE B O   1 
ATOM   4100 C  CB  . PHE B 1 123 ? 110.311 131.315 161.620 1.00 56.18  ? 123 PHE B CB  1 
ATOM   4101 C  CG  . PHE B 1 123 ? 110.224 132.797 161.415 1.00 56.81  ? 123 PHE B CG  1 
ATOM   4102 C  CD1 . PHE B 1 123 ? 110.709 133.376 160.258 1.00 55.14  ? 123 PHE B CD1 1 
ATOM   4103 C  CD2 . PHE B 1 123 ? 109.657 133.612 162.376 1.00 56.41  ? 123 PHE B CD2 1 
ATOM   4104 C  CE1 . PHE B 1 123 ? 110.629 134.734 160.064 1.00 55.48  ? 123 PHE B CE1 1 
ATOM   4105 C  CE2 . PHE B 1 123 ? 109.576 134.971 162.185 1.00 57.51  ? 123 PHE B CE2 1 
ATOM   4106 C  CZ  . PHE B 1 123 ? 110.061 135.532 161.028 1.00 57.79  ? 123 PHE B CZ  1 
ATOM   4107 N  N   . GLU B 1 124 ? 112.993 130.237 163.175 1.00 56.12  ? 124 GLU B N   1 
ATOM   4108 C  CA  . GLU B 1 124 ? 114.041 130.542 164.140 1.00 53.68  ? 124 GLU B CA  1 
ATOM   4109 C  C   . GLU B 1 124 ? 115.431 130.347 163.555 1.00 56.51  ? 124 GLU B C   1 
ATOM   4110 O  O   . GLU B 1 124 ? 116.378 131.004 163.997 1.00 59.62  ? 124 GLU B O   1 
ATOM   4111 C  CB  . GLU B 1 124 ? 113.870 129.685 165.393 1.00 57.69  ? 124 GLU B CB  1 
ATOM   4112 C  CG  . GLU B 1 124 ? 112.905 130.271 166.406 1.00 64.22  ? 124 GLU B CG  1 
ATOM   4113 C  CD  . GLU B 1 124 ? 111.457 130.129 165.986 1.00 66.30  ? 124 GLU B CD  1 
ATOM   4114 O  OE1 . GLU B 1 124 ? 111.172 129.313 165.085 1.00 63.88  ? 124 GLU B OE1 1 
ATOM   4115 O  OE2 . GLU B 1 124 ? 110.604 130.841 166.554 1.00 66.90  ? 124 GLU B OE2 1 
ATOM   4116 N  N   . GLN B 1 125 ? 115.579 129.448 162.582 1.00 52.99  ? 125 GLN B N   1 
ATOM   4117 C  CA  . GLN B 1 125 ? 116.862 129.290 161.910 1.00 46.70  ? 125 GLN B CA  1 
ATOM   4118 C  C   . GLN B 1 125 ? 117.105 130.403 160.903 1.00 46.74  ? 125 GLN B C   1 
ATOM   4119 O  O   . GLN B 1 125 ? 118.238 130.867 160.752 1.00 54.73  ? 125 GLN B O   1 
ATOM   4120 C  CB  . GLN B 1 125 ? 116.933 127.932 161.219 1.00 46.36  ? 125 GLN B CB  1 
ATOM   4121 C  CG  . GLN B 1 125 ? 117.362 126.801 162.119 1.00 48.59  ? 125 GLN B CG  1 
ATOM   4122 C  CD  . GLN B 1 125 ? 117.271 125.459 161.439 1.00 50.67  ? 125 GLN B CD  1 
ATOM   4123 O  OE1 . GLN B 1 125 ? 118.276 124.781 161.246 1.00 54.50  ? 125 GLN B OE1 1 
ATOM   4124 N  NE2 . GLN B 1 125 ? 116.062 125.064 161.072 1.00 50.52  ? 125 GLN B NE2 1 
ATOM   4125 N  N   . VAL B 1 126 ? 116.061 130.832 160.194 1.00 45.34  ? 126 VAL B N   1 
ATOM   4126 C  CA  . VAL B 1 126 ? 116.224 131.907 159.223 1.00 46.51  ? 126 VAL B CA  1 
ATOM   4127 C  C   . VAL B 1 126 ? 116.490 133.228 159.930 1.00 50.56  ? 126 VAL B C   1 
ATOM   4128 O  O   . VAL B 1 126 ? 117.312 134.034 159.481 1.00 51.99  ? 126 VAL B O   1 
ATOM   4129 C  CB  . VAL B 1 126 ? 114.994 131.987 158.305 1.00 45.13  ? 126 VAL B CB  1 
ATOM   4130 C  CG1 . VAL B 1 126 ? 115.125 133.150 157.351 1.00 48.78  ? 126 VAL B CG1 1 
ATOM   4131 C  CG2 . VAL B 1 126 ? 114.839 130.701 157.537 1.00 44.57  ? 126 VAL B CG2 1 
ATOM   4132 N  N   . LYS B 1 127 ? 115.801 133.474 161.044 1.00 57.61  ? 127 LYS B N   1 
ATOM   4133 C  CA  . LYS B 1 127 ? 116.071 134.675 161.823 1.00 56.74  ? 127 LYS B CA  1 
ATOM   4134 C  C   . LYS B 1 127 ? 117.471 134.640 162.421 1.00 57.49  ? 127 LYS B C   1 
ATOM   4135 O  O   . LYS B 1 127 ? 118.155 135.668 162.470 1.00 62.73  ? 127 LYS B O   1 
ATOM   4136 C  CB  . LYS B 1 127 ? 115.017 134.836 162.914 1.00 57.72  ? 127 LYS B CB  1 
ATOM   4137 C  CG  . LYS B 1 127 ? 113.872 135.751 162.526 1.00 58.27  ? 127 LYS B CG  1 
ATOM   4138 C  CD  . LYS B 1 127 ? 114.361 137.165 162.291 1.00 59.17  ? 127 LYS B CD  1 
ATOM   4139 C  CE  . LYS B 1 127 ? 113.217 138.100 161.956 1.00 59.75  ? 127 LYS B CE  1 
ATOM   4140 N  NZ  . LYS B 1 127 ? 113.642 139.526 162.008 1.00 60.35  ? 127 LYS B NZ  1 
ATOM   4141 N  N   . SER B 1 128 ? 117.916 133.469 162.882 1.00 56.10  ? 128 SER B N   1 
ATOM   4142 C  CA  . SER B 1 128 ? 119.284 133.339 163.370 1.00 52.41  ? 128 SER B CA  1 
ATOM   4143 C  C   . SER B 1 128 ? 120.298 133.518 162.251 1.00 55.65  ? 128 SER B C   1 
ATOM   4144 O  O   . SER B 1 128 ? 121.414 133.985 162.498 1.00 62.19  ? 128 SER B O   1 
ATOM   4145 C  CB  . SER B 1 128 ? 119.479 131.981 164.039 1.00 56.91  ? 128 SER B CB  1 
ATOM   4146 O  OG  . SER B 1 128 ? 119.215 132.057 165.427 1.00 65.12  ? 128 SER B OG  1 
ATOM   4147 N  N   . LEU B 1 129 ? 119.940 133.136 161.025 1.00 54.15  ? 129 LEU B N   1 
ATOM   4148 C  CA  . LEU B 1 129 ? 120.818 133.369 159.884 1.00 48.99  ? 129 LEU B CA  1 
ATOM   4149 C  C   . LEU B 1 129 ? 120.936 134.854 159.573 1.00 52.42  ? 129 LEU B C   1 
ATOM   4150 O  O   . LEU B 1 129 ? 122.025 135.342 159.254 1.00 57.66  ? 129 LEU B O   1 
ATOM   4151 C  CB  . LEU B 1 129 ? 120.298 132.604 158.668 1.00 50.48  ? 129 LEU B CB  1 
ATOM   4152 C  CG  . LEU B 1 129 ? 121.256 132.324 157.513 1.00 53.20  ? 129 LEU B CG  1 
ATOM   4153 C  CD1 . LEU B 1 129 ? 120.853 131.045 156.811 1.00 52.19  ? 129 LEU B CD1 1 
ATOM   4154 C  CD2 . LEU B 1 129 ? 121.260 133.482 156.536 1.00 53.94  ? 129 LEU B CD2 1 
ATOM   4155 N  N   . MET B 1 130 ? 119.823 135.586 159.649 1.00 61.36  ? 130 MET B N   1 
ATOM   4156 C  CA  . MET B 1 130 ? 119.850 137.018 159.368 1.00 60.84  ? 130 MET B CA  1 
ATOM   4157 C  C   . MET B 1 130 ? 120.662 137.773 160.408 1.00 61.47  ? 130 MET B C   1 
ATOM   4158 O  O   . MET B 1 130 ? 121.384 138.716 160.070 1.00 65.03  ? 130 MET B O   1 
ATOM   4159 C  CB  . MET B 1 130 ? 118.430 137.570 159.311 1.00 60.56  ? 130 MET B CB  1 
ATOM   4160 C  CG  . MET B 1 130 ? 117.646 137.147 158.094 1.00 60.58  ? 130 MET B CG  1 
ATOM   4161 S  SD  . MET B 1 130 ? 115.943 137.714 158.167 1.00 76.32  ? 130 MET B SD  1 
ATOM   4162 C  CE  . MET B 1 130 ? 116.050 139.010 159.397 1.00 62.02  ? 130 MET B CE  1 
ATOM   4163 N  N   . TYR B 1 131 ? 120.545 137.387 161.680 1.00 62.13  ? 131 TYR B N   1 
ATOM   4164 C  CA  . TYR B 1 131 ? 121.325 138.048 162.719 1.00 61.82  ? 131 TYR B CA  1 
ATOM   4165 C  C   . TYR B 1 131 ? 122.812 137.780 162.550 1.00 66.42  ? 131 TYR B C   1 
ATOM   4166 O  O   . TYR B 1 131 ? 123.637 138.614 162.935 1.00 72.39  ? 131 TYR B O   1 
ATOM   4167 C  CB  . TYR B 1 131 ? 120.866 137.596 164.103 1.00 61.01  ? 131 TYR B CB  1 
ATOM   4168 C  CG  . TYR B 1 131 ? 119.399 137.816 164.384 1.00 64.52  ? 131 TYR B CG  1 
ATOM   4169 C  CD1 . TYR B 1 131 ? 118.660 138.747 163.669 1.00 64.98  ? 131 TYR B CD1 1 
ATOM   4170 C  CD2 . TYR B 1 131 ? 118.752 137.090 165.370 1.00 66.54  ? 131 TYR B CD2 1 
ATOM   4171 C  CE1 . TYR B 1 131 ? 117.321 138.943 163.928 1.00 67.55  ? 131 TYR B CE1 1 
ATOM   4172 C  CE2 . TYR B 1 131 ? 117.417 137.279 165.635 1.00 66.91  ? 131 TYR B CE2 1 
ATOM   4173 C  CZ  . TYR B 1 131 ? 116.706 138.205 164.913 1.00 67.09  ? 131 TYR B CZ  1 
ATOM   4174 O  OH  . TYR B 1 131 ? 115.371 138.392 165.182 1.00 64.35  ? 131 TYR B OH  1 
ATOM   4175 N  N   . TRP B 1 132 ? 123.174 136.623 161.994 1.00 58.28  ? 132 TRP B N   1 
ATOM   4176 C  CA  . TRP B 1 132 ? 124.574 136.364 161.680 1.00 57.32  ? 132 TRP B CA  1 
ATOM   4177 C  C   . TRP B 1 132 ? 125.079 137.313 160.601 1.00 58.35  ? 132 TRP B C   1 
ATOM   4178 O  O   . TRP B 1 132 ? 126.202 137.820 160.691 1.00 62.91  ? 132 TRP B O   1 
ATOM   4179 C  CB  . TRP B 1 132 ? 124.754 134.910 161.248 1.00 57.76  ? 132 TRP B CB  1 
ATOM   4180 C  CG  . TRP B 1 132 ? 126.172 134.546 160.947 1.00 60.36  ? 132 TRP B CG  1 
ATOM   4181 C  CD1 . TRP B 1 132 ? 127.096 134.067 161.823 1.00 61.06  ? 132 TRP B CD1 1 
ATOM   4182 C  CD2 . TRP B 1 132 ? 126.828 134.632 159.678 1.00 60.24  ? 132 TRP B CD2 1 
ATOM   4183 N  NE1 . TRP B 1 132 ? 128.290 133.852 161.181 1.00 61.77  ? 132 TRP B NE1 1 
ATOM   4184 C  CE2 . TRP B 1 132 ? 128.150 134.190 159.862 1.00 58.08  ? 132 TRP B CE2 1 
ATOM   4185 C  CE3 . TRP B 1 132 ? 126.426 135.040 158.404 1.00 61.99  ? 132 TRP B CE3 1 
ATOM   4186 C  CZ2 . TRP B 1 132 ? 129.070 134.145 158.824 1.00 57.26  ? 132 TRP B CZ2 1 
ATOM   4187 C  CZ3 . TRP B 1 132 ? 127.343 134.996 157.375 1.00 62.71  ? 132 TRP B CZ3 1 
ATOM   4188 C  CH2 . TRP B 1 132 ? 128.648 134.552 157.590 1.00 58.43  ? 132 TRP B CH2 1 
ATOM   4189 N  N   . LEU B 1 133 ? 124.267 137.562 159.571 1.00 58.41  ? 133 LEU B N   1 
ATOM   4190 C  CA  . LEU B 1 133 ? 124.660 138.504 158.528 1.00 58.67  ? 133 LEU B CA  1 
ATOM   4191 C  C   . LEU B 1 133 ? 124.839 139.904 159.093 1.00 62.11  ? 133 LEU B C   1 
ATOM   4192 O  O   . LEU B 1 133 ? 125.816 140.591 158.775 1.00 68.63  ? 133 LEU B O   1 
ATOM   4193 C  CB  . LEU B 1 133 ? 123.619 138.517 157.411 1.00 59.94  ? 133 LEU B CB  1 
ATOM   4194 C  CG  . LEU B 1 133 ? 123.942 137.745 156.134 1.00 60.21  ? 133 LEU B CG  1 
ATOM   4195 C  CD1 . LEU B 1 133 ? 122.819 137.917 155.131 1.00 60.03  ? 133 LEU B CD1 1 
ATOM   4196 C  CD2 . LEU B 1 133 ? 125.258 138.205 155.546 1.00 59.32  ? 133 LEU B CD2 1 
ATOM   4197 N  N   . ASP B 1 134 ? 123.906 140.345 159.925 1.00 64.64  ? 134 ASP B N   1 
ATOM   4198 C  CA  . ASP B 1 134 ? 124.003 141.640 160.582 1.00 66.70  ? 134 ASP B CA  1 
ATOM   4199 C  C   . ASP B 1 134 ? 123.481 141.523 162.007 1.00 67.29  ? 134 ASP B C   1 
ATOM   4200 O  O   . ASP B 1 134 ? 122.272 141.370 162.214 1.00 69.68  ? 134 ASP B O   1 
ATOM   4201 C  CB  . ASP B 1 134 ? 123.222 142.703 159.812 1.00 69.73  ? 134 ASP B CB  1 
ATOM   4202 C  CG  . ASP B 1 134 ? 123.637 144.111 160.182 1.00 72.59  ? 134 ASP B CG  1 
ATOM   4203 O  OD1 . ASP B 1 134 ? 124.272 144.289 161.241 1.00 70.57  ? 134 ASP B OD1 1 
ATOM   4204 O  OD2 . ASP B 1 134 ? 123.327 145.045 159.416 1.00 73.62  ? 134 ASP B OD2 1 
ATOM   4205 N  N   . PRO B 1 135 ? 124.358 141.576 163.010 1.00 73.50  ? 135 PRO B N   1 
ATOM   4206 C  CA  . PRO B 1 135 ? 123.880 141.544 164.402 1.00 74.45  ? 135 PRO B CA  1 
ATOM   4207 C  C   . PRO B 1 135 ? 122.968 142.704 164.753 1.00 77.12  ? 135 PRO B C   1 
ATOM   4208 O  O   . PRO B 1 135 ? 122.169 142.581 165.688 1.00 74.69  ? 135 PRO B O   1 
ATOM   4209 C  CB  . PRO B 1 135 ? 125.169 141.585 165.235 1.00 74.92  ? 135 PRO B CB  1 
ATOM   4210 C  CG  . PRO B 1 135 ? 126.297 141.425 164.294 1.00 75.80  ? 135 PRO B CG  1 
ATOM   4211 C  CD  . PRO B 1 135 ? 125.815 141.422 162.889 1.00 72.94  ? 135 PRO B CD  1 
ATOM   4212 N  N   . ASN B 1 136 ? 123.059 143.827 164.037 1.00 85.31  ? 136 ASN B N   1 
ATOM   4213 C  CA  . ASN B 1 136 ? 122.207 144.976 164.310 1.00 85.63  ? 136 ASN B CA  1 
ATOM   4214 C  C   . ASN B 1 136 ? 120.752 144.742 163.929 1.00 85.54  ? 136 ASN B C   1 
ATOM   4215 O  O   . ASN B 1 136 ? 119.898 145.556 164.292 1.00 83.67  ? 136 ASN B O   1 
ATOM   4216 C  CB  . ASN B 1 136 ? 122.739 146.207 163.576 1.00 84.52  ? 136 ASN B CB  1 
ATOM   4217 C  CG  . ASN B 1 136 ? 124.090 146.654 164.093 1.00 87.09  ? 136 ASN B CG  1 
ATOM   4218 O  OD1 . ASN B 1 136 ? 124.952 145.831 164.395 1.00 86.13  ? 136 ASN B OD1 1 
ATOM   4219 N  ND2 . ASN B 1 136 ? 124.281 147.963 164.199 1.00 87.47  ? 136 ASN B ND2 1 
ATOM   4220 N  N   . LEU B 1 137 ? 120.450 143.666 163.203 1.00 80.71  ? 137 LEU B N   1 
ATOM   4221 C  CA  . LEU B 1 137 ? 119.068 143.341 162.880 1.00 77.13  ? 137 LEU B CA  1 
ATOM   4222 C  C   . LEU B 1 137 ? 118.322 142.733 164.058 1.00 77.17  ? 137 LEU B C   1 
ATOM   4223 O  O   . LEU B 1 137 ? 117.087 142.732 164.059 1.00 76.19  ? 137 LEU B O   1 
ATOM   4224 C  CB  . LEU B 1 137 ? 119.016 142.376 161.696 1.00 73.82  ? 137 LEU B CB  1 
ATOM   4225 C  CG  . LEU B 1 137 ? 119.215 142.982 160.309 1.00 71.49  ? 137 LEU B CG  1 
ATOM   4226 C  CD1 . LEU B 1 137 ? 119.022 141.927 159.240 1.00 73.25  ? 137 LEU B CD1 1 
ATOM   4227 C  CD2 . LEU B 1 137 ? 118.265 144.139 160.100 1.00 75.21  ? 137 LEU B CD2 1 
ATOM   4228 N  N   . ARG B 1 138 ? 119.043 142.214 165.052 1.00 81.02  ? 138 ARG B N   1 
ATOM   4229 C  CA  . ARG B 1 138 ? 118.389 141.584 166.192 1.00 80.86  ? 138 ARG B CA  1 
ATOM   4230 C  C   . ARG B 1 138 ? 117.727 142.619 167.090 1.00 83.61  ? 138 ARG B C   1 
ATOM   4231 O  O   . ARG B 1 138 ? 116.603 142.413 167.563 1.00 83.18  ? 138 ARG B O   1 
ATOM   4232 C  CB  . ARG B 1 138 ? 119.406 140.761 166.981 1.00 80.94  ? 138 ARG B CB  1 
ATOM   4233 C  CG  . ARG B 1 138 ? 118.797 139.786 167.971 1.00 80.80  ? 138 ARG B CG  1 
ATOM   4234 C  CD  . ARG B 1 138 ? 119.826 139.322 168.988 1.00 82.34  ? 138 ARG B CD  1 
ATOM   4235 N  NE  . ARG B 1 138 ? 120.544 138.136 168.538 1.00 84.16  ? 138 ARG B NE  1 
ATOM   4236 C  CZ  . ARG B 1 138 ? 121.696 138.159 167.883 1.00 84.34  ? 138 ARG B CZ  1 
ATOM   4237 N  NH1 . ARG B 1 138 ? 122.302 139.297 167.591 1.00 86.76  ? 138 ARG B NH1 1 
ATOM   4238 N  NH2 . ARG B 1 138 ? 122.256 137.011 167.513 1.00 81.60  ? 138 ARG B NH2 1 
ATOM   4239 N  N   . TYR B 1 139 ? 118.408 143.736 167.334 1.00 93.09  ? 139 TYR B N   1 
ATOM   4240 C  CA  . TYR B 1 139 ? 117.904 144.742 168.260 1.00 94.18  ? 139 TYR B CA  1 
ATOM   4241 C  C   . TYR B 1 139 ? 116.802 145.591 167.643 1.00 93.33  ? 139 TYR B C   1 
ATOM   4242 O  O   . TYR B 1 139 ? 115.929 146.083 168.366 1.00 93.02  ? 139 TYR B O   1 
ATOM   4243 C  CB  . TYR B 1 139 ? 119.064 145.612 168.743 1.00 92.56  ? 139 TYR B CB  1 
ATOM   4244 C  CG  . TYR B 1 139 ? 120.355 144.833 168.867 1.00 95.38  ? 139 TYR B CG  1 
ATOM   4245 C  CD1 . TYR B 1 139 ? 120.437 143.716 169.694 1.00 94.15  ? 139 TYR B CD1 1 
ATOM   4246 C  CD2 . TYR B 1 139 ? 121.483 145.194 168.142 1.00 94.20  ? 139 TYR B CD2 1 
ATOM   4247 C  CE1 . TYR B 1 139 ? 121.608 142.991 169.803 1.00 92.86  ? 139 TYR B CE1 1 
ATOM   4248 C  CE2 . TYR B 1 139 ? 122.660 144.474 168.247 1.00 94.53  ? 139 TYR B CE2 1 
ATOM   4249 C  CZ  . TYR B 1 139 ? 122.716 143.374 169.078 1.00 94.93  ? 139 TYR B CZ  1 
ATOM   4250 O  OH  . TYR B 1 139 ? 123.884 142.654 169.186 1.00 92.78  ? 139 TYR B OH  1 
ATOM   4251 N  N   . ALA B 1 140 ? 116.817 145.768 166.326 1.00 90.01  ? 140 ALA B N   1 
ATOM   4252 C  CA  . ALA B 1 140 ? 115.777 146.528 165.643 1.00 90.66  ? 140 ALA B CA  1 
ATOM   4253 C  C   . ALA B 1 140 ? 114.443 145.790 165.689 1.00 90.19  ? 140 ALA B C   1 
ATOM   4254 O  O   . ALA B 1 140 ? 113.946 145.322 164.666 1.00 90.11  ? 140 ALA B O   1 
ATOM   4255 C  CB  . ALA B 1 140 ? 116.180 146.804 164.205 1.00 90.80  ? 140 ALA B CB  1 
ATOM   4256 N  N   . GLU B 1 159 ? 106.550 171.273 150.883 1.00 131.80 ? 159 GLU B N   1 
ATOM   4257 C  CA  . GLU B 1 159 ? 107.551 171.127 151.932 1.00 132.56 ? 159 GLU B CA  1 
ATOM   4258 C  C   . GLU B 1 159 ? 107.671 169.672 152.367 1.00 132.21 ? 159 GLU B C   1 
ATOM   4259 O  O   . GLU B 1 159 ? 108.750 169.083 152.307 1.00 131.25 ? 159 GLU B O   1 
ATOM   4260 C  CB  . GLU B 1 159 ? 107.205 172.010 153.133 1.00 131.94 ? 159 GLU B CB  1 
ATOM   4261 C  CG  . GLU B 1 159 ? 107.372 173.499 152.877 1.00 132.04 ? 159 GLU B CG  1 
ATOM   4262 C  CD  . GLU B 1 159 ? 106.180 174.111 152.167 1.00 132.59 ? 159 GLU B CD  1 
ATOM   4263 O  OE1 . GLU B 1 159 ? 105.197 173.382 151.912 1.00 132.75 ? 159 GLU B OE1 1 
ATOM   4264 O  OE2 . GLU B 1 159 ? 106.224 175.322 151.864 1.00 132.25 ? 159 GLU B OE2 1 
ATOM   4265 N  N   . ARG B 1 160 ? 106.550 169.101 152.814 1.00 128.35 ? 160 ARG B N   1 
ATOM   4266 C  CA  . ARG B 1 160 ? 106.535 167.694 153.201 1.00 127.99 ? 160 ARG B CA  1 
ATOM   4267 C  C   . ARG B 1 160 ? 106.793 166.786 152.005 1.00 127.20 ? 160 ARG B C   1 
ATOM   4268 O  O   . ARG B 1 160 ? 107.521 165.793 152.117 1.00 125.19 ? 160 ARG B O   1 
ATOM   4269 C  CB  . ARG B 1 160 ? 105.200 167.353 153.863 1.00 126.75 ? 160 ARG B CB  1 
ATOM   4270 C  CG  . ARG B 1 160 ? 105.033 165.893 154.248 1.00 126.58 ? 160 ARG B CG  1 
ATOM   4271 C  CD  . ARG B 1 160 ? 103.693 165.675 154.925 1.00 127.59 ? 160 ARG B CD  1 
ATOM   4272 N  NE  . ARG B 1 160 ? 103.274 164.280 154.901 1.00 127.60 ? 160 ARG B NE  1 
ATOM   4273 C  CZ  . ARG B 1 160 ? 102.120 163.840 155.384 1.00 127.40 ? 160 ARG B CZ  1 
ATOM   4274 N  NH1 . ARG B 1 160 ? 101.248 164.661 155.946 1.00 125.63 ? 160 ARG B NH1 1 
ATOM   4275 N  NH2 . ARG B 1 160 ? 101.834 162.543 155.301 1.00 127.49 ? 160 ARG B NH2 1 
ATOM   4276 N  N   . ILE B 1 161 ? 106.204 167.111 150.852 1.00 124.46 ? 161 ILE B N   1 
ATOM   4277 C  CA  . ILE B 1 161 ? 106.422 166.309 149.651 1.00 123.95 ? 161 ILE B CA  1 
ATOM   4278 C  C   . ILE B 1 161 ? 107.885 166.360 149.234 1.00 123.50 ? 161 ILE B C   1 
ATOM   4279 O  O   . ILE B 1 161 ? 108.442 165.371 148.744 1.00 123.92 ? 161 ILE B O   1 
ATOM   4280 C  CB  . ILE B 1 161 ? 105.492 166.779 148.518 1.00 123.14 ? 161 ILE B CB  1 
ATOM   4281 C  CG1 . ILE B 1 161 ? 104.089 167.054 149.061 1.00 123.70 ? 161 ILE B CG1 1 
ATOM   4282 C  CG2 . ILE B 1 161 ? 105.444 165.747 147.404 1.00 121.86 ? 161 ILE B CG2 1 
ATOM   4283 C  CD1 . ILE B 1 161 ? 103.078 167.408 147.994 1.00 123.13 ? 161 ILE B CD1 1 
ATOM   4284 N  N   . ILE B 1 162 ? 108.528 167.516 149.413 1.00 123.70 ? 162 ILE B N   1 
ATOM   4285 C  CA  . ILE B 1 162 ? 109.946 167.637 149.084 1.00 124.45 ? 162 ILE B CA  1 
ATOM   4286 C  C   . ILE B 1 162 ? 110.776 166.710 149.962 1.00 124.68 ? 162 ILE B C   1 
ATOM   4287 O  O   . ILE B 1 162 ? 111.708 166.051 149.487 1.00 123.82 ? 162 ILE B O   1 
ATOM   4288 C  CB  . ILE B 1 162 ? 110.401 169.102 149.215 1.00 124.34 ? 162 ILE B CB  1 
ATOM   4289 C  CG1 . ILE B 1 162 ? 109.299 170.045 148.731 1.00 124.25 ? 162 ILE B CG1 1 
ATOM   4290 C  CG2 . ILE B 1 162 ? 111.678 169.332 148.428 1.00 123.42 ? 162 ILE B CG2 1 
ATOM   4291 C  CD1 . ILE B 1 162 ? 109.643 171.511 148.877 1.00 123.69 ? 162 ILE B CD1 1 
ATOM   4292 N  N   . SER B 1 163 ? 110.456 166.649 151.256 1.00 124.96 ? 163 SER B N   1 
ATOM   4293 C  CA  . SER B 1 163 ? 111.159 165.744 152.156 1.00 124.66 ? 163 SER B CA  1 
ATOM   4294 C  C   . SER B 1 163 ? 110.843 164.282 151.869 1.00 124.06 ? 163 SER B C   1 
ATOM   4295 O  O   . SER B 1 163 ? 111.633 163.408 152.240 1.00 123.51 ? 163 SER B O   1 
ATOM   4296 C  CB  . SER B 1 163 ? 110.820 166.077 153.610 1.00 124.62 ? 163 SER B CB  1 
ATOM   4297 O  OG  . SER B 1 163 ? 109.462 165.792 153.900 1.00 125.45 ? 163 SER B OG  1 
ATOM   4298 N  N   . HIS B 1 164 ? 109.706 163.998 151.227 1.00 121.71 ? 164 HIS B N   1 
ATOM   4299 C  CA  . HIS B 1 164 ? 109.381 162.620 150.872 1.00 121.71 ? 164 HIS B CA  1 
ATOM   4300 C  C   . HIS B 1 164 ? 110.360 162.066 149.845 1.00 121.40 ? 164 HIS B C   1 
ATOM   4301 O  O   . HIS B 1 164 ? 110.749 160.895 149.921 1.00 121.48 ? 164 HIS B O   1 
ATOM   4302 C  CB  . HIS B 1 164 ? 107.950 162.535 150.344 1.00 122.33 ? 164 HIS B CB  1 
ATOM   4303 C  CG  . HIS B 1 164 ? 106.944 162.150 151.383 1.00 123.93 ? 164 HIS B CG  1 
ATOM   4304 N  ND1 . HIS B 1 164 ? 106.726 162.896 152.521 1.00 123.05 ? 164 HIS B ND1 1 
ATOM   4305 C  CD2 . HIS B 1 164 ? 106.094 161.098 151.454 1.00 123.31 ? 164 HIS B CD2 1 
ATOM   4306 C  CE1 . HIS B 1 164 ? 105.786 162.321 153.249 1.00 122.71 ? 164 HIS B CE1 1 
ATOM   4307 N  NE2 . HIS B 1 164 ? 105.385 161.228 152.624 1.00 123.63 ? 164 HIS B NE2 1 
ATOM   4308 N  N   . PHE B 1 165 ? 110.766 162.887 148.878 1.00 116.72 ? 165 PHE B N   1 
ATOM   4309 C  CA  . PHE B 1 165 ? 111.708 162.456 147.850 1.00 116.78 ? 165 PHE B CA  1 
ATOM   4310 C  C   . PHE B 1 165 ? 113.067 162.186 148.481 1.00 115.90 ? 165 PHE B C   1 
ATOM   4311 O  O   . PHE B 1 165 ? 113.779 163.118 148.870 1.00 115.37 ? 165 PHE B O   1 
ATOM   4312 C  CB  . PHE B 1 165 ? 111.814 163.510 146.754 1.00 115.44 ? 165 PHE B CB  1 
ATOM   4313 C  CG  . PHE B 1 165 ? 110.536 163.728 146.002 1.00 115.12 ? 165 PHE B CG  1 
ATOM   4314 C  CD1 . PHE B 1 165 ? 109.944 162.689 145.305 1.00 114.59 ? 165 PHE B CD1 1 
ATOM   4315 C  CD2 . PHE B 1 165 ? 109.923 164.969 145.993 1.00 115.52 ? 165 PHE B CD2 1 
ATOM   4316 C  CE1 . PHE B 1 165 ? 108.765 162.883 144.612 1.00 115.60 ? 165 PHE B CE1 1 
ATOM   4317 C  CE2 . PHE B 1 165 ? 108.744 165.169 145.302 1.00 115.66 ? 165 PHE B CE2 1 
ATOM   4318 C  CZ  . PHE B 1 165 ? 108.165 164.124 144.609 1.00 116.04 ? 165 PHE B CZ  1 
ATOM   4319 N  N   . ASP B 1 166 ? 113.428 160.913 148.579 1.00 101.41 ? 166 ASP B N   1 
ATOM   4320 C  CA  . ASP B 1 166 ? 114.689 160.472 149.155 1.00 99.36  ? 166 ASP B CA  1 
ATOM   4321 C  C   . ASP B 1 166 ? 115.492 159.732 148.089 1.00 98.58  ? 166 ASP B C   1 
ATOM   4322 O  O   . ASP B 1 166 ? 115.119 159.696 146.914 1.00 100.25 ? 166 ASP B O   1 
ATOM   4323 C  CB  . ASP B 1 166 ? 114.433 159.597 150.383 1.00 99.97  ? 166 ASP B CB  1 
ATOM   4324 C  CG  . ASP B 1 166 ? 113.209 158.722 150.224 1.00 101.76 ? 166 ASP B CG  1 
ATOM   4325 O  OD1 . ASP B 1 166 ? 112.527 158.843 149.186 1.00 99.67  ? 166 ASP B OD1 1 
ATOM   4326 O  OD2 . ASP B 1 166 ? 112.927 157.915 151.134 1.00 102.19 ? 166 ASP B OD2 1 
ATOM   4327 N  N   . ILE B 1 167 ? 116.612 159.138 148.509 1.00 90.46  ? 167 ILE B N   1 
ATOM   4328 C  CA  . ILE B 1 167 ? 117.417 158.348 147.588 1.00 90.35  ? 167 ILE B CA  1 
ATOM   4329 C  C   . ILE B 1 167 ? 116.655 157.126 147.104 1.00 90.03  ? 167 ILE B C   1 
ATOM   4330 O  O   . ILE B 1 167 ? 116.976 156.575 146.047 1.00 90.89  ? 167 ILE B O   1 
ATOM   4331 C  CB  . ILE B 1 167 ? 118.755 157.950 148.247 1.00 92.29  ? 167 ILE B CB  1 
ATOM   4332 C  CG1 . ILE B 1 167 ? 119.739 157.431 147.197 1.00 90.75  ? 167 ILE B CG1 1 
ATOM   4333 C  CG2 . ILE B 1 167 ? 118.533 156.914 149.334 1.00 92.09  ? 167 ILE B CG2 1 
ATOM   4334 C  CD1 . ILE B 1 167 ? 121.156 157.304 147.700 1.00 89.01  ? 167 ILE B CD1 1 
ATOM   4335 N  N   . PHE B 1 168 ? 115.644 156.684 147.855 1.00 87.26  ? 168 PHE B N   1 
ATOM   4336 C  CA  . PHE B 1 168 ? 114.819 155.570 147.399 1.00 87.35  ? 168 PHE B CA  1 
ATOM   4337 C  C   . PHE B 1 168 ? 113.871 156.004 146.289 1.00 86.03  ? 168 PHE B C   1 
ATOM   4338 O  O   . PHE B 1 168 ? 113.640 155.251 145.336 1.00 85.42  ? 168 PHE B O   1 
ATOM   4339 C  CB  . PHE B 1 168 ? 114.044 154.977 148.573 1.00 86.31  ? 168 PHE B CB  1 
ATOM   4340 C  CG  . PHE B 1 168 ? 114.921 154.451 149.670 1.00 87.13  ? 168 PHE B CG  1 
ATOM   4341 C  CD1 . PHE B 1 168 ? 115.919 153.532 149.396 1.00 87.32  ? 168 PHE B CD1 1 
ATOM   4342 C  CD2 . PHE B 1 168 ? 114.752 154.878 150.974 1.00 88.40  ? 168 PHE B CD2 1 
ATOM   4343 C  CE1 . PHE B 1 168 ? 116.729 153.049 150.400 1.00 89.06  ? 168 PHE B CE1 1 
ATOM   4344 C  CE2 . PHE B 1 168 ? 115.558 154.398 151.982 1.00 88.85  ? 168 PHE B CE2 1 
ATOM   4345 C  CZ  . PHE B 1 168 ? 116.548 153.483 151.694 1.00 88.62  ? 168 PHE B CZ  1 
ATOM   4346 N  N   . ALA B 1 169 ? 113.313 157.212 146.393 1.00 85.36  ? 169 ALA B N   1 
ATOM   4347 C  CA  . ALA B 1 169 ? 112.455 157.724 145.330 1.00 85.32  ? 169 ALA B CA  1 
ATOM   4348 C  C   . ALA B 1 169 ? 113.215 157.866 144.021 1.00 81.51  ? 169 ALA B C   1 
ATOM   4349 O  O   . ALA B 1 169 ? 112.642 157.671 142.945 1.00 82.65  ? 169 ALA B O   1 
ATOM   4350 C  CB  . ALA B 1 169 ? 111.849 159.065 145.740 1.00 85.95  ? 169 ALA B CB  1 
ATOM   4351 N  N   . PHE B 1 170 ? 114.500 158.214 144.090 1.00 83.68  ? 170 PHE B N   1 
ATOM   4352 C  CA  . PHE B 1 170 ? 115.325 158.240 142.890 1.00 82.60  ? 170 PHE B CA  1 
ATOM   4353 C  C   . PHE B 1 170 ? 115.472 156.843 142.303 1.00 84.31  ? 170 PHE B C   1 
ATOM   4354 O  O   . PHE B 1 170 ? 115.434 156.668 141.081 1.00 86.67  ? 170 PHE B O   1 
ATOM   4355 C  CB  . PHE B 1 170 ? 116.695 158.836 143.212 1.00 84.33  ? 170 PHE B CB  1 
ATOM   4356 C  CG  . PHE B 1 170 ? 117.339 159.541 142.056 1.00 84.49  ? 170 PHE B CG  1 
ATOM   4357 C  CD1 . PHE B 1 170 ? 116.567 160.138 141.074 1.00 86.12  ? 170 PHE B CD1 1 
ATOM   4358 C  CD2 . PHE B 1 170 ? 118.716 159.617 141.956 1.00 85.13  ? 170 PHE B CD2 1 
ATOM   4359 C  CE1 . PHE B 1 170 ? 117.157 160.794 140.012 1.00 86.75  ? 170 PHE B CE1 1 
ATOM   4360 C  CE2 . PHE B 1 170 ? 119.313 160.270 140.896 1.00 86.49  ? 170 PHE B CE2 1 
ATOM   4361 C  CZ  . PHE B 1 170 ? 118.532 160.859 139.923 1.00 86.75  ? 170 PHE B CZ  1 
ATOM   4362 N  N   . GLY B 1 171 ? 115.652 155.836 143.160 1.00 81.66  ? 171 GLY B N   1 
ATOM   4363 C  CA  . GLY B 1 171 ? 115.725 154.469 142.673 1.00 78.06  ? 171 GLY B CA  1 
ATOM   4364 C  C   . GLY B 1 171 ? 114.403 153.973 142.119 1.00 80.36  ? 171 GLY B C   1 
ATOM   4365 O  O   . GLY B 1 171 ? 114.372 153.229 141.136 1.00 80.04  ? 171 GLY B O   1 
ATOM   4366 N  N   . HIS B 1 172 ? 113.294 154.368 142.747 1.00 82.41  ? 172 HIS B N   1 
ATOM   4367 C  CA  . HIS B 1 172 ? 111.980 153.980 142.245 1.00 80.30  ? 172 HIS B CA  1 
ATOM   4368 C  C   . HIS B 1 172 ? 111.696 154.627 140.896 1.00 76.42  ? 172 HIS B C   1 
ATOM   4369 O  O   . HIS B 1 172 ? 111.064 154.017 140.028 1.00 75.86  ? 172 HIS B O   1 
ATOM   4370 C  CB  . HIS B 1 172 ? 110.901 154.357 143.257 1.00 79.66  ? 172 HIS B CB  1 
ATOM   4371 C  CG  . HIS B 1 172 ? 109.904 153.272 143.508 1.00 82.62  ? 172 HIS B CG  1 
ATOM   4372 N  ND1 . HIS B 1 172 ? 108.924 152.937 142.599 1.00 83.45  ? 172 HIS B ND1 1 
ATOM   4373 C  CD2 . HIS B 1 172 ? 109.735 152.444 144.565 1.00 82.48  ? 172 HIS B CD2 1 
ATOM   4374 C  CE1 . HIS B 1 172 ? 108.194 151.949 143.085 1.00 83.52  ? 172 HIS B CE1 1 
ATOM   4375 N  NE2 . HIS B 1 172 ? 108.665 151.632 144.278 1.00 85.98  ? 172 HIS B NE2 1 
ATOM   4376 N  N   . PHE B 1 173 ? 112.137 155.872 140.711 1.00 67.99  ? 173 PHE B N   1 
ATOM   4377 C  CA  . PHE B 1 173 ? 111.973 156.532 139.422 1.00 64.20  ? 173 PHE B CA  1 
ATOM   4378 C  C   . PHE B 1 173 ? 112.786 155.837 138.340 1.00 63.16  ? 173 PHE B C   1 
ATOM   4379 O  O   . PHE B 1 173 ? 112.296 155.628 137.226 1.00 70.57  ? 173 PHE B O   1 
ATOM   4380 C  CB  . PHE B 1 173 ? 112.372 158.003 139.537 1.00 64.22  ? 173 PHE B CB  1 
ATOM   4381 C  CG  . PHE B 1 173 ? 112.611 158.676 138.218 1.00 63.85  ? 173 PHE B CG  1 
ATOM   4382 C  CD1 . PHE B 1 173 ? 111.566 159.252 137.524 1.00 62.88  ? 173 PHE B CD1 1 
ATOM   4383 C  CD2 . PHE B 1 173 ? 113.883 158.751 137.681 1.00 66.87  ? 173 PHE B CD2 1 
ATOM   4384 C  CE1 . PHE B 1 173 ? 111.781 159.876 136.316 1.00 61.67  ? 173 PHE B CE1 1 
ATOM   4385 C  CE2 . PHE B 1 173 ? 114.100 159.370 136.472 1.00 66.46  ? 173 PHE B CE2 1 
ATOM   4386 C  CZ  . PHE B 1 173 ? 113.049 159.935 135.791 1.00 62.81  ? 173 PHE B CZ  1 
ATOM   4387 N  N   . TRP B 1 174 ? 114.031 155.474 138.644 1.00 60.87  ? 174 TRP B N   1 
ATOM   4388 C  CA  . TRP B 1 174 ? 114.875 154.817 137.657 1.00 63.41  ? 174 TRP B CA  1 
ATOM   4389 C  C   . TRP B 1 174 ? 114.519 153.352 137.467 1.00 66.55  ? 174 TRP B C   1 
ATOM   4390 O  O   . TRP B 1 174 ? 114.898 152.765 136.450 1.00 68.68  ? 174 TRP B O   1 
ATOM   4391 C  CB  . TRP B 1 174 ? 116.345 154.946 138.051 1.00 68.01  ? 174 TRP B CB  1 
ATOM   4392 C  CG  . TRP B 1 174 ? 116.904 156.299 137.778 1.00 67.64  ? 174 TRP B CG  1 
ATOM   4393 C  CD1 . TRP B 1 174 ? 117.215 157.253 138.696 1.00 68.42  ? 174 TRP B CD1 1 
ATOM   4394 C  CD2 . TRP B 1 174 ? 117.211 156.859 136.498 1.00 69.70  ? 174 TRP B CD2 1 
ATOM   4395 N  NE1 . TRP B 1 174 ? 117.701 158.372 138.069 1.00 68.53  ? 174 TRP B NE1 1 
ATOM   4396 C  CE2 . TRP B 1 174 ? 117.707 158.155 136.718 1.00 69.53  ? 174 TRP B CE2 1 
ATOM   4397 C  CE3 . TRP B 1 174 ? 117.117 156.387 135.187 1.00 69.12  ? 174 TRP B CE3 1 
ATOM   4398 C  CZ2 . TRP B 1 174 ? 118.109 158.986 135.679 1.00 69.68  ? 174 TRP B CZ2 1 
ATOM   4399 C  CZ3 . TRP B 1 174 ? 117.515 157.213 134.157 1.00 68.85  ? 174 TRP B CZ3 1 
ATOM   4400 C  CH2 . TRP B 1 174 ? 118.005 158.498 134.408 1.00 70.77  ? 174 TRP B CH2 1 
ATOM   4401 N  N   . GLY B 1 175 ? 113.820 152.744 138.423 1.00 58.00  ? 175 GLY B N   1 
ATOM   4402 C  CA  . GLY B 1 175 ? 113.315 151.401 138.205 1.00 51.15  ? 175 GLY B CA  1 
ATOM   4403 C  C   . GLY B 1 175 ? 112.252 151.358 137.126 1.00 53.44  ? 175 GLY B C   1 
ATOM   4404 O  O   . GLY B 1 175 ? 112.250 150.464 136.279 1.00 57.97  ? 175 GLY B O   1 
ATOM   4405 N  N   . TRP B 1 176 ? 111.333 152.325 137.142 1.00 55.58  ? 176 TRP B N   1 
ATOM   4406 C  CA  . TRP B 1 176 ? 110.317 152.401 136.099 1.00 46.11  ? 176 TRP B CA  1 
ATOM   4407 C  C   . TRP B 1 176 ? 110.907 152.895 134.787 1.00 52.00  ? 176 TRP B C   1 
ATOM   4408 O  O   . TRP B 1 176 ? 110.496 152.452 133.709 1.00 56.57  ? 176 TRP B O   1 
ATOM   4409 C  CB  . TRP B 1 176 ? 109.178 153.310 136.551 1.00 47.40  ? 176 TRP B CB  1 
ATOM   4410 C  CG  . TRP B 1 176 ? 108.203 152.629 137.437 1.00 50.10  ? 176 TRP B CG  1 
ATOM   4411 C  CD1 . TRP B 1 176 ? 108.023 152.841 138.767 1.00 52.15  ? 176 TRP B CD1 1 
ATOM   4412 C  CD2 . TRP B 1 176 ? 107.270 151.614 137.061 1.00 51.80  ? 176 TRP B CD2 1 
ATOM   4413 N  NE1 . TRP B 1 176 ? 107.034 152.022 139.246 1.00 53.22  ? 176 TRP B NE1 1 
ATOM   4414 C  CE2 . TRP B 1 176 ? 106.555 151.258 138.216 1.00 53.24  ? 176 TRP B CE2 1 
ATOM   4415 C  CE3 . TRP B 1 176 ? 106.970 150.972 135.858 1.00 51.89  ? 176 TRP B CE3 1 
ATOM   4416 C  CZ2 . TRP B 1 176 ? 105.560 150.291 138.205 1.00 51.23  ? 176 TRP B CZ2 1 
ATOM   4417 C  CZ3 . TRP B 1 176 ? 105.984 150.013 135.851 1.00 52.45  ? 176 TRP B CZ3 1 
ATOM   4418 C  CH2 . TRP B 1 176 ? 105.288 149.683 137.015 1.00 50.57  ? 176 TRP B CH2 1 
ATOM   4419 N  N   . ALA B 1 177 ? 111.872 153.813 134.856 1.00 50.76  ? 177 ALA B N   1 
ATOM   4420 C  CA  . ALA B 1 177 ? 112.551 154.275 133.653 1.00 49.08  ? 177 ALA B CA  1 
ATOM   4421 C  C   . ALA B 1 177 ? 113.358 153.173 132.986 1.00 52.10  ? 177 ALA B C   1 
ATOM   4422 O  O   . ALA B 1 177 ? 113.739 153.322 131.822 1.00 58.33  ? 177 ALA B O   1 
ATOM   4423 C  CB  . ALA B 1 177 ? 113.458 155.458 133.984 1.00 48.46  ? 177 ALA B CB  1 
ATOM   4424 N  N   . MET B 1 178 ? 113.638 152.083 133.697 1.00 49.22  ? 178 MET B N   1 
ATOM   4425 C  CA  . MET B 1 178 ? 114.280 150.911 133.119 1.00 46.30  ? 178 MET B CA  1 
ATOM   4426 C  C   . MET B 1 178 ? 113.285 149.826 132.739 1.00 47.48  ? 178 MET B C   1 
ATOM   4427 O  O   . MET B 1 178 ? 113.473 149.154 131.723 1.00 49.51  ? 178 MET B O   1 
ATOM   4428 C  CB  . MET B 1 178 ? 115.315 150.337 134.092 1.00 46.86  ? 178 MET B CB  1 
ATOM   4429 C  CG  . MET B 1 178 ? 115.982 149.058 133.612 1.00 52.17  ? 178 MET B CG  1 
ATOM   4430 S  SD  . MET B 1 178 ? 116.312 147.899 134.950 1.00 70.22  ? 178 MET B SD  1 
ATOM   4431 C  CE  . MET B 1 178 ? 114.963 146.744 134.740 1.00 50.76  ? 178 MET B CE  1 
ATOM   4432 N  N   . LYS B 1 179 ? 112.227 149.634 133.528 1.00 47.36  ? 179 LYS B N   1 
ATOM   4433 C  CA  . LYS B 1 179 ? 111.200 148.670 133.151 1.00 41.66  ? 179 LYS B CA  1 
ATOM   4434 C  C   . LYS B 1 179 ? 110.512 149.090 131.862 1.00 42.95  ? 179 LYS B C   1 
ATOM   4435 O  O   . LYS B 1 179 ? 110.444 148.316 130.903 1.00 54.36  ? 179 LYS B O   1 
ATOM   4436 C  CB  . LYS B 1 179 ? 110.176 148.511 134.273 1.00 42.89  ? 179 LYS B CB  1 
ATOM   4437 C  CG  . LYS B 1 179 ? 110.694 147.803 135.507 1.00 47.99  ? 179 LYS B CG  1 
ATOM   4438 C  CD  . LYS B 1 179 ? 109.829 148.143 136.706 1.00 47.78  ? 179 LYS B CD  1 
ATOM   4439 C  CE  . LYS B 1 179 ? 110.469 147.707 138.007 1.00 47.13  ? 179 LYS B CE  1 
ATOM   4440 N  NZ  . LYS B 1 179 ? 109.719 148.235 139.179 1.00 49.76  ? 179 LYS B NZ  1 
ATOM   4441 N  N   . ALA B 1 180 ? 110.025 150.330 131.808 1.00 42.91  ? 180 ALA B N   1 
ATOM   4442 C  CA  . ALA B 1 180 ? 109.367 150.824 130.605 1.00 40.42  ? 180 ALA B CA  1 
ATOM   4443 C  C   . ALA B 1 180 ? 110.302 150.837 129.406 1.00 40.42  ? 180 ALA B C   1 
ATOM   4444 O  O   . ALA B 1 180 ? 109.831 150.864 128.266 1.00 31.37  ? 180 ALA B O   1 
ATOM   4445 C  CB  . ALA B 1 180 ? 108.814 152.226 130.849 1.00 42.00  ? 180 ALA B CB  1 
ATOM   4446 N  N   . LEU B 1 181 ? 111.613 150.819 129.644 1.00 48.81  ? 181 LEU B N   1 
ATOM   4447 C  CA  . LEU B 1 181 ? 112.577 150.766 128.553 1.00 37.84  ? 181 LEU B CA  1 
ATOM   4448 C  C   . LEU B 1 181 ? 112.551 149.421 127.842 1.00 37.83  ? 181 LEU B C   1 
ATOM   4449 O  O   . LEU B 1 181 ? 112.878 149.343 126.654 1.00 43.46  ? 181 LEU B O   1 
ATOM   4450 C  CB  . LEU B 1 181 ? 113.976 151.063 129.087 1.00 36.51  ? 181 LEU B CB  1 
ATOM   4451 C  CG  . LEU B 1 181 ? 115.114 151.093 128.076 1.00 38.72  ? 181 LEU B CG  1 
ATOM   4452 C  CD1 . LEU B 1 181 ? 114.979 152.303 127.192 1.00 45.60  ? 181 LEU B CD1 1 
ATOM   4453 C  CD2 . LEU B 1 181 ? 116.445 151.101 128.787 1.00 42.75  ? 181 LEU B CD2 1 
ATOM   4454 N  N   . LEU B 1 182 ? 112.165 148.358 128.542 1.00 37.89  ? 182 LEU B N   1 
ATOM   4455 C  CA  . LEU B 1 182 ? 112.154 147.012 127.984 1.00 39.02  ? 182 LEU B CA  1 
ATOM   4456 C  C   . LEU B 1 182 ? 110.756 146.510 127.655 1.00 46.22  ? 182 LEU B C   1 
ATOM   4457 O  O   . LEU B 1 182 ? 110.580 145.790 126.670 1.00 47.01  ? 182 LEU B O   1 
ATOM   4458 C  CB  . LEU B 1 182 ? 112.826 146.040 128.955 1.00 36.25  ? 182 LEU B CB  1 
ATOM   4459 C  CG  . LEU B 1 182 ? 114.182 146.494 129.482 1.00 40.64  ? 182 LEU B CG  1 
ATOM   4460 C  CD1 . LEU B 1 182 ? 114.342 146.083 130.925 1.00 41.56  ? 182 LEU B CD1 1 
ATOM   4461 C  CD2 . LEU B 1 182 ? 115.287 145.908 128.635 1.00 34.54  ? 182 LEU B CD2 1 
ATOM   4462 N  N   . ILE B 1 183 ? 109.758 146.855 128.469 1.00 45.39  ? 183 ILE B N   1 
ATOM   4463 C  CA  . ILE B 1 183 ? 108.388 146.464 128.162 1.00 32.46  ? 183 ILE B CA  1 
ATOM   4464 C  C   . ILE B 1 183 ? 107.876 147.218 126.945 1.00 38.13  ? 183 ILE B C   1 
ATOM   4465 O  O   . ILE B 1 183 ? 107.149 146.660 126.117 1.00 49.25  ? 183 ILE B O   1 
ATOM   4466 C  CB  . ILE B 1 183 ? 107.477 146.683 129.380 1.00 32.34  ? 183 ILE B CB  1 
ATOM   4467 C  CG1 . ILE B 1 183 ? 108.193 146.290 130.667 1.00 32.66  ? 183 ILE B CG1 1 
ATOM   4468 C  CG2 . ILE B 1 183 ? 106.212 145.892 129.229 1.00 46.89  ? 183 ILE B CG2 1 
ATOM   4469 C  CD1 . ILE B 1 183 ? 108.363 144.822 130.841 1.00 34.29  ? 183 ILE B CD1 1 
ATOM   4470 N  N   . ARG B 1 184 ? 108.234 148.494 126.824 1.00 44.26  ? 184 ARG B N   1 
ATOM   4471 C  CA  . ARG B 1 184 ? 107.843 149.338 125.698 1.00 51.05  ? 184 ARG B CA  1 
ATOM   4472 C  C   . ARG B 1 184 ? 106.323 149.319 125.535 1.00 54.80  ? 184 ARG B C   1 
ATOM   4473 O  O   . ARG B 1 184 ? 105.771 148.790 124.570 1.00 54.79  ? 184 ARG B O   1 
ATOM   4474 C  CB  . ARG B 1 184 ? 108.573 148.898 124.422 1.00 53.71  ? 184 ARG B CB  1 
ATOM   4475 C  CG  . ARG B 1 184 ? 108.717 149.937 123.291 1.00 50.87  ? 184 ARG B CG  1 
ATOM   4476 C  CD  . ARG B 1 184 ? 107.427 150.244 122.546 1.00 54.87  ? 184 ARG B CD  1 
ATOM   4477 N  NE  . ARG B 1 184 ? 107.654 151.010 121.326 1.00 57.75  ? 184 ARG B NE  1 
ATOM   4478 C  CZ  . ARG B 1 184 ? 107.696 152.334 121.264 1.00 59.34  ? 184 ARG B CZ  1 
ATOM   4479 N  NH1 . ARG B 1 184 ? 107.541 153.081 122.343 1.00 56.26  ? 184 ARG B NH1 1 
ATOM   4480 N  NH2 . ARG B 1 184 ? 107.898 152.921 120.089 1.00 58.23  ? 184 ARG B NH2 1 
ATOM   4481 N  N   . SER B 1 185 ? 105.647 149.865 126.547 1.00 49.60  ? 185 SER B N   1 
ATOM   4482 C  CA  . SER B 1 185 ? 104.196 149.993 126.529 1.00 46.88  ? 185 SER B CA  1 
ATOM   4483 C  C   . SER B 1 185 ? 103.716 150.895 127.656 1.00 48.74  ? 185 SER B C   1 
ATOM   4484 O  O   . SER B 1 185 ? 104.116 150.717 128.810 1.00 52.47  ? 185 SER B O   1 
ATOM   4485 C  CB  . SER B 1 185 ? 103.529 148.622 126.642 1.00 46.49  ? 185 SER B CB  1 
ATOM   4486 O  OG  . SER B 1 185 ? 102.121 148.740 126.588 1.00 48.04  ? 185 SER B OG  1 
ATOM   4487 N  N   . TYR B 1 186 ? 102.870 151.875 127.333 1.00 59.92  ? 186 TYR B N   1 
ATOM   4488 C  CA  . TYR B 1 186 ? 102.214 152.658 128.374 1.00 57.96  ? 186 TYR B CA  1 
ATOM   4489 C  C   . TYR B 1 186 ? 101.112 151.852 129.047 1.00 55.52  ? 186 TYR B C   1 
ATOM   4490 O  O   . TYR B 1 186 ? 100.939 151.920 130.267 1.00 57.25  ? 186 TYR B O   1 
ATOM   4491 C  CB  . TYR B 1 186 ? 101.630 153.941 127.787 1.00 59.14  ? 186 TYR B CB  1 
ATOM   4492 C  CG  . TYR B 1 186 ? 102.630 155.036 127.511 1.00 54.89  ? 186 TYR B CG  1 
ATOM   4493 C  CD1 . TYR B 1 186 ? 103.161 155.794 128.539 1.00 58.06  ? 186 TYR B CD1 1 
ATOM   4494 C  CD2 . TYR B 1 186 ? 103.023 155.324 126.217 1.00 50.86  ? 186 TYR B CD2 1 
ATOM   4495 C  CE1 . TYR B 1 186 ? 104.068 156.800 128.285 1.00 58.27  ? 186 TYR B CE1 1 
ATOM   4496 C  CE2 . TYR B 1 186 ? 103.925 156.326 125.955 1.00 56.86  ? 186 TYR B CE2 1 
ATOM   4497 C  CZ  . TYR B 1 186 ? 104.446 157.060 126.990 1.00 58.68  ? 186 TYR B CZ  1 
ATOM   4498 O  OH  . TYR B 1 186 ? 105.348 158.060 126.725 1.00 59.73  ? 186 TYR B OH  1 
ATOM   4499 N  N   . GLY B 1 187 ? 100.350 151.092 128.262 1.00 51.48  ? 187 GLY B N   1 
ATOM   4500 C  CA  . GLY B 1 187 ? 99.237  150.347 128.823 1.00 51.99  ? 187 GLY B CA  1 
ATOM   4501 C  C   . GLY B 1 187 ? 99.676  149.246 129.767 1.00 51.46  ? 187 GLY B C   1 
ATOM   4502 O  O   . GLY B 1 187 ? 99.003  148.967 130.760 1.00 55.86  ? 187 GLY B O   1 
ATOM   4503 N  N   . LEU B 1 188 ? 100.798 148.590 129.462 1.00 51.46  ? 188 LEU B N   1 
ATOM   4504 C  CA  . LEU B 1 188 ? 101.298 147.543 130.345 1.00 49.12  ? 188 LEU B CA  1 
ATOM   4505 C  C   . LEU B 1 188 ? 101.906 148.131 131.610 1.00 51.16  ? 188 LEU B C   1 
ATOM   4506 O  O   . LEU B 1 188 ? 101.702 147.601 132.707 1.00 57.36  ? 188 LEU B O   1 
ATOM   4507 C  CB  . LEU B 1 188 ? 102.326 146.680 129.614 1.00 46.74  ? 188 LEU B CB  1 
ATOM   4508 C  CG  . LEU B 1 188 ? 101.874 145.276 129.210 1.00 49.88  ? 188 LEU B CG  1 
ATOM   4509 C  CD1 . LEU B 1 188 ? 100.781 145.333 128.164 1.00 46.27  ? 188 LEU B CD1 1 
ATOM   4510 C  CD2 . LEU B 1 188 ? 103.043 144.451 128.715 1.00 48.87  ? 188 LEU B CD2 1 
ATOM   4511 N  N   . CYS B 1 189 ? 102.651 149.227 131.480 1.00 44.35  ? 189 CYS B N   1 
ATOM   4512 C  CA  . CYS B 1 189 ? 103.359 149.781 132.627 1.00 39.34  ? 189 CYS B CA  1 
ATOM   4513 C  C   . CYS B 1 189 ? 102.422 150.529 133.564 1.00 44.46  ? 189 CYS B C   1 
ATOM   4514 O  O   . CYS B 1 189 ? 102.605 150.487 134.783 1.00 54.37  ? 189 CYS B O   1 
ATOM   4515 C  CB  . CYS B 1 189 ? 104.489 150.690 132.152 1.00 45.92  ? 189 CYS B CB  1 
ATOM   4516 S  SG  . CYS B 1 189 ? 105.838 149.810 131.338 1.00 52.26  ? 189 CYS B SG  1 
ATOM   4517 N  N   . TRP B 1 190 ? 101.421 151.222 133.025 1.00 49.84  ? 190 TRP B N   1 
ATOM   4518 C  CA  . TRP B 1 190 ? 100.469 151.917 133.884 1.00 48.19  ? 190 TRP B CA  1 
ATOM   4519 C  C   . TRP B 1 190 ? 99.473  150.962 134.522 1.00 46.59  ? 190 TRP B C   1 
ATOM   4520 O  O   . TRP B 1 190 ? 98.952  151.251 135.602 1.00 50.23  ? 190 TRP B O   1 
ATOM   4521 C  CB  . TRP B 1 190 ? 99.732  152.994 133.092 1.00 46.10  ? 190 TRP B CB  1 
ATOM   4522 C  CG  . TRP B 1 190 ? 100.470 154.283 133.037 1.00 43.69  ? 190 TRP B CG  1 
ATOM   4523 C  CD1 . TRP B 1 190 ? 101.354 154.675 132.084 1.00 46.44  ? 190 TRP B CD1 1 
ATOM   4524 C  CD2 . TRP B 1 190 ? 100.394 155.354 133.980 1.00 47.78  ? 190 TRP B CD2 1 
ATOM   4525 N  NE1 . TRP B 1 190 ? 101.836 155.925 132.370 1.00 49.94  ? 190 TRP B NE1 1 
ATOM   4526 C  CE2 . TRP B 1 190 ? 101.260 156.365 133.532 1.00 50.07  ? 190 TRP B CE2 1 
ATOM   4527 C  CE3 . TRP B 1 190 ? 99.675  155.558 135.159 1.00 51.90  ? 190 TRP B CE3 1 
ATOM   4528 C  CZ2 . TRP B 1 190 ? 101.428 157.560 134.219 1.00 49.62  ? 190 TRP B CZ2 1 
ATOM   4529 C  CZ3 . TRP B 1 190 ? 99.844  156.743 135.840 1.00 53.13  ? 190 TRP B CZ3 1 
ATOM   4530 C  CH2 . TRP B 1 190 ? 100.713 157.729 135.369 1.00 52.01  ? 190 TRP B CH2 1 
ATOM   4531 N  N   . THR B 1 191 ? 99.192  149.832 133.872 1.00 49.96  ? 191 THR B N   1 
ATOM   4532 C  CA  . THR B 1 191 ? 98.311  148.832 134.462 1.00 45.12  ? 191 THR B CA  1 
ATOM   4533 C  C   . THR B 1 191 ? 98.899  148.274 135.747 1.00 55.71  ? 191 THR B C   1 
ATOM   4534 O  O   . THR B 1 191 ? 98.182  148.067 136.730 1.00 59.55  ? 191 THR B O   1 
ATOM   4535 C  CB  . THR B 1 191 ? 98.065  147.701 133.471 1.00 50.69  ? 191 THR B CB  1 
ATOM   4536 O  OG1 . THR B 1 191 ? 97.505  148.238 132.269 1.00 62.67  ? 191 THR B OG1 1 
ATOM   4537 C  CG2 . THR B 1 191 ? 97.118  146.674 134.056 1.00 54.91  ? 191 THR B CG2 1 
ATOM   4538 N  N   . ILE B 1 192 ? 100.203 148.022 135.757 1.00 54.11  ? 192 ILE B N   1 
ATOM   4539 C  CA  . ILE B 1 192 ? 100.837 147.442 136.930 1.00 50.97  ? 192 ILE B CA  1 
ATOM   4540 C  C   . ILE B 1 192 ? 101.316 148.510 137.909 1.00 51.03  ? 192 ILE B C   1 
ATOM   4541 O  O   . ILE B 1 192 ? 101.333 148.274 139.121 1.00 56.39  ? 192 ILE B O   1 
ATOM   4542 C  CB  . ILE B 1 192 ? 101.971 146.508 136.483 1.00 38.74  ? 192 ILE B CB  1 
ATOM   4543 C  CG1 . ILE B 1 192 ? 101.366 145.155 136.134 1.00 37.70  ? 192 ILE B CG1 1 
ATOM   4544 C  CG2 . ILE B 1 192 ? 103.035 146.365 137.552 1.00 43.89  ? 192 ILE B CG2 1 
ATOM   4545 C  CD1 . ILE B 1 192 ? 102.297 144.231 135.478 1.00 46.87  ? 192 ILE B CD1 1 
ATOM   4546 N  N   . SER B 1 193 ? 101.666 149.698 137.419 1.00 46.96  ? 193 SER B N   1 
ATOM   4547 C  CA  . SER B 1 193 ? 101.933 150.804 138.329 1.00 44.34  ? 193 SER B CA  1 
ATOM   4548 C  C   . SER B 1 193 ? 100.701 151.136 139.156 1.00 47.41  ? 193 SER B C   1 
ATOM   4549 O  O   . SER B 1 193 ? 100.801 151.369 140.363 1.00 58.57  ? 193 SER B O   1 
ATOM   4550 C  CB  . SER B 1 193 ? 102.397 152.030 137.547 1.00 52.73  ? 193 SER B CB  1 
ATOM   4551 O  OG  . SER B 1 193 ? 102.283 153.206 138.325 1.00 57.89  ? 193 SER B OG  1 
ATOM   4552 N  N   . ILE B 1 194 ? 99.528  151.151 138.528 1.00 41.64  ? 194 ILE B N   1 
ATOM   4553 C  CA  . ILE B 1 194 ? 98.307  151.514 139.237 1.00 44.69  ? 194 ILE B CA  1 
ATOM   4554 C  C   . ILE B 1 194 ? 97.856  150.390 140.162 1.00 48.83  ? 194 ILE B C   1 
ATOM   4555 O  O   . ILE B 1 194 ? 97.522  150.628 141.326 1.00 57.13  ? 194 ILE B O   1 
ATOM   4556 C  CB  . ILE B 1 194 ? 97.207  151.903 138.233 1.00 50.01  ? 194 ILE B CB  1 
ATOM   4557 C  CG1 . ILE B 1 194 ? 97.288  153.396 137.914 1.00 53.32  ? 194 ILE B CG1 1 
ATOM   4558 C  CG2 . ILE B 1 194 ? 95.828  151.550 138.768 1.00 50.54  ? 194 ILE B CG2 1 
ATOM   4559 C  CD1 . ILE B 1 194 ? 96.659  153.773 136.594 1.00 52.78  ? 194 ILE B CD1 1 
ATOM   4560 N  N   . THR B 1 195 ? 97.837  149.150 139.665 1.00 48.06  ? 195 THR B N   1 
ATOM   4561 C  CA  . THR B 1 195 ? 97.322  148.043 140.470 1.00 50.98  ? 195 THR B CA  1 
ATOM   4562 C  C   . THR B 1 195 ? 98.172  147.807 141.711 1.00 52.53  ? 195 THR B C   1 
ATOM   4563 O  O   . THR B 1 195 ? 97.638  147.535 142.791 1.00 51.48  ? 195 THR B O   1 
ATOM   4564 C  CB  . THR B 1 195 ? 97.239  146.760 139.641 1.00 49.16  ? 195 THR B CB  1 
ATOM   4565 O  OG1 . THR B 1 195 ? 98.465  146.564 138.931 1.00 44.41  ? 195 THR B OG1 1 
ATOM   4566 C  CG2 . THR B 1 195 ? 96.074  146.811 138.666 1.00 54.82  ? 195 THR B CG2 1 
ATOM   4567 N  N   . TRP B 1 196 ? 99.495  147.892 141.578 1.00 52.88  ? 196 TRP B N   1 
ATOM   4568 C  CA  . TRP B 1 196 ? 100.353 147.630 142.728 1.00 47.36  ? 196 TRP B CA  1 
ATOM   4569 C  C   . TRP B 1 196 ? 100.211 148.715 143.786 1.00 53.41  ? 196 TRP B C   1 
ATOM   4570 O  O   . TRP B 1 196 ? 100.072 148.415 144.977 1.00 57.88  ? 196 TRP B O   1 
ATOM   4571 C  CB  . TRP B 1 196 ? 101.810 147.500 142.299 1.00 47.36  ? 196 TRP B CB  1 
ATOM   4572 C  CG  . TRP B 1 196 ? 102.724 147.464 143.473 1.00 47.91  ? 196 TRP B CG  1 
ATOM   4573 C  CD1 . TRP B 1 196 ? 103.738 148.325 143.744 1.00 51.35  ? 196 TRP B CD1 1 
ATOM   4574 C  CD2 . TRP B 1 196 ? 102.692 146.528 144.556 1.00 51.12  ? 196 TRP B CD2 1 
ATOM   4575 N  NE1 . TRP B 1 196 ? 104.348 147.982 144.922 1.00 53.17  ? 196 TRP B NE1 1 
ATOM   4576 C  CE2 . TRP B 1 196 ? 103.722 146.881 145.441 1.00 51.11  ? 196 TRP B CE2 1 
ATOM   4577 C  CE3 . TRP B 1 196 ? 101.896 145.420 144.859 1.00 53.19  ? 196 TRP B CE3 1 
ATOM   4578 C  CZ2 . TRP B 1 196 ? 103.978 146.170 146.605 1.00 53.04  ? 196 TRP B CZ2 1 
ATOM   4579 C  CZ3 . TRP B 1 196 ? 102.151 144.720 146.014 1.00 49.72  ? 196 TRP B CZ3 1 
ATOM   4580 C  CH2 . TRP B 1 196 ? 103.180 145.096 146.874 1.00 51.38  ? 196 TRP B CH2 1 
ATOM   4581 N  N   . GLU B 1 197 ? 100.249 149.985 143.376 1.00 58.89  ? 197 GLU B N   1 
ATOM   4582 C  CA  . GLU B 1 197 ? 100.099 151.067 144.342 1.00 61.06  ? 197 GLU B CA  1 
ATOM   4583 C  C   . GLU B 1 197 ? 98.751  150.989 145.044 1.00 64.62  ? 197 GLU B C   1 
ATOM   4584 O  O   . GLU B 1 197 ? 98.637  151.320 146.228 1.00 68.55  ? 197 GLU B O   1 
ATOM   4585 C  CB  . GLU B 1 197 ? 100.267 152.418 143.654 1.00 57.65  ? 197 GLU B CB  1 
ATOM   4586 C  CG  . GLU B 1 197 ? 101.627 152.655 143.025 1.00 58.73  ? 197 GLU B CG  1 
ATOM   4587 C  CD  . GLU B 1 197 ? 102.773 152.084 143.829 1.00 64.77  ? 197 GLU B CD  1 
ATOM   4588 O  OE1 . GLU B 1 197 ? 102.891 152.417 145.025 1.00 68.82  ? 197 GLU B OE1 1 
ATOM   4589 O  OE2 . GLU B 1 197 ? 103.571 151.314 143.257 1.00 63.45  ? 197 GLU B OE2 1 
ATOM   4590 N  N   . LEU B 1 198 ? 97.715  150.557 144.326 1.00 54.81  ? 198 LEU B N   1 
ATOM   4591 C  CA  . LEU B 1 198 ? 96.438  150.280 144.969 1.00 52.03  ? 198 LEU B CA  1 
ATOM   4592 C  C   . LEU B 1 198 ? 96.570  149.145 145.974 1.00 57.42  ? 198 LEU B C   1 
ATOM   4593 O  O   . LEU B 1 198 ? 95.981  149.196 147.059 1.00 64.03  ? 198 LEU B O   1 
ATOM   4594 C  CB  . LEU B 1 198 ? 95.386  149.939 143.916 1.00 53.00  ? 198 LEU B CB  1 
ATOM   4595 C  CG  . LEU B 1 198 ? 94.381  151.025 143.545 1.00 59.24  ? 198 LEU B CG  1 
ATOM   4596 C  CD1 . LEU B 1 198 ? 95.076  152.349 143.288 1.00 58.31  ? 198 LEU B CD1 1 
ATOM   4597 C  CD2 . LEU B 1 198 ? 93.584  150.594 142.330 1.00 57.36  ? 198 LEU B CD2 1 
ATOM   4598 N  N   . THR B 1 199 ? 97.335  148.108 145.628 1.00 57.44  ? 199 THR B N   1 
ATOM   4599 C  CA  . THR B 1 199 ? 97.490  146.965 146.522 1.00 56.78  ? 199 THR B CA  1 
ATOM   4600 C  C   . THR B 1 199 ? 98.276  147.345 147.770 1.00 60.70  ? 199 THR B C   1 
ATOM   4601 O  O   . THR B 1 199 ? 97.878  147.010 148.891 1.00 62.03  ? 199 THR B O   1 
ATOM   4602 C  CB  . THR B 1 199 ? 98.170  145.812 145.786 1.00 54.08  ? 199 THR B CB  1 
ATOM   4603 O  OG1 . THR B 1 199 ? 97.205  145.114 144.993 1.00 60.49  ? 199 THR B OG1 1 
ATOM   4604 C  CG2 . THR B 1 199 ? 98.779  144.841 146.768 1.00 56.29  ? 199 THR B CG2 1 
ATOM   4605 N  N   . GLU B 1 200 ? 99.393  148.054 147.597 1.00 66.88  ? 200 GLU B N   1 
ATOM   4606 C  CA  . GLU B 1 200 ? 100.180 148.479 148.750 1.00 64.73  ? 200 GLU B CA  1 
ATOM   4607 C  C   . GLU B 1 200 ? 99.410  149.461 149.620 1.00 70.92  ? 200 GLU B C   1 
ATOM   4608 O  O   . GLU B 1 200 ? 99.609  149.497 150.838 1.00 72.04  ? 200 GLU B O   1 
ATOM   4609 C  CB  . GLU B 1 200 ? 101.499 149.091 148.290 1.00 60.39  ? 200 GLU B CB  1 
ATOM   4610 C  CG  . GLU B 1 200 ? 102.704 148.478 148.965 1.00 67.77  ? 200 GLU B CG  1 
ATOM   4611 C  CD  . GLU B 1 200 ? 104.014 149.019 148.439 1.00 71.77  ? 200 GLU B CD  1 
ATOM   4612 O  OE1 . GLU B 1 200 ? 103.988 149.960 147.622 1.00 73.38  ? 200 GLU B OE1 1 
ATOM   4613 O  OE2 . GLU B 1 200 ? 105.075 148.497 148.841 1.00 70.14  ? 200 GLU B OE2 1 
ATOM   4614 N  N   . LEU B 1 201 ? 98.538  150.270 149.017 1.00 68.72  ? 201 LEU B N   1 
ATOM   4615 C  CA  . LEU B 1 201 ? 97.635  151.100 149.806 1.00 66.25  ? 201 LEU B CA  1 
ATOM   4616 C  C   . LEU B 1 201 ? 96.682  150.240 150.626 1.00 67.14  ? 201 LEU B C   1 
ATOM   4617 O  O   . LEU B 1 201 ? 96.399  150.545 151.790 1.00 67.80  ? 201 LEU B O   1 
ATOM   4618 C  CB  . LEU B 1 201 ? 96.857  152.040 148.890 1.00 67.50  ? 201 LEU B CB  1 
ATOM   4619 C  CG  . LEU B 1 201 ? 95.705  152.814 149.530 1.00 70.89  ? 201 LEU B CG  1 
ATOM   4620 C  CD1 . LEU B 1 201 ? 96.212  153.691 150.664 1.00 67.50  ? 201 LEU B CD1 1 
ATOM   4621 C  CD2 . LEU B 1 201 ? 94.971  153.640 148.488 1.00 70.06  ? 201 LEU B CD2 1 
ATOM   4622 N  N   . PHE B 1 202 ? 96.170  149.163 150.031 1.00 62.52  ? 202 PHE B N   1 
ATOM   4623 C  CA  . PHE B 1 202 ? 95.304  148.250 150.766 1.00 61.15  ? 202 PHE B CA  1 
ATOM   4624 C  C   . PHE B 1 202 ? 96.098  147.428 151.770 1.00 69.38  ? 202 PHE B C   1 
ATOM   4625 O  O   . PHE B 1 202 ? 95.679  147.261 152.921 1.00 73.56  ? 202 PHE B O   1 
ATOM   4626 C  CB  . PHE B 1 202 ? 94.567  147.335 149.792 1.00 60.76  ? 202 PHE B CB  1 
ATOM   4627 C  CG  . PHE B 1 202 ? 93.920  146.151 150.443 1.00 65.07  ? 202 PHE B CG  1 
ATOM   4628 C  CD1 . PHE B 1 202 ? 92.790  146.305 151.223 1.00 64.72  ? 202 PHE B CD1 1 
ATOM   4629 C  CD2 . PHE B 1 202 ? 94.439  144.883 150.271 1.00 66.86  ? 202 PHE B CD2 1 
ATOM   4630 C  CE1 . PHE B 1 202 ? 92.193  145.217 151.819 1.00 67.54  ? 202 PHE B CE1 1 
ATOM   4631 C  CE2 . PHE B 1 202 ? 93.847  143.793 150.866 1.00 66.97  ? 202 PHE B CE2 1 
ATOM   4632 C  CZ  . PHE B 1 202 ? 92.721  143.960 151.640 1.00 69.37  ? 202 PHE B CZ  1 
ATOM   4633 N  N   . PHE B 1 203 ? 97.254  146.905 151.356 1.00 68.71  ? 203 PHE B N   1 
ATOM   4634 C  CA  . PHE B 1 203 ? 98.042  146.049 152.234 1.00 65.52  ? 203 PHE B CA  1 
ATOM   4635 C  C   . PHE B 1 203 ? 98.635  146.802 153.412 1.00 64.90  ? 203 PHE B C   1 
ATOM   4636 O  O   . PHE B 1 203 ? 99.138  146.162 154.339 1.00 71.97  ? 203 PHE B O   1 
ATOM   4637 C  CB  . PHE B 1 203 ? 99.159  145.367 151.447 1.00 63.08  ? 203 PHE B CB  1 
ATOM   4638 C  CG  . PHE B 1 203 ? 98.758  144.055 150.853 1.00 64.14  ? 203 PHE B CG  1 
ATOM   4639 C  CD1 . PHE B 1 203 ? 97.531  143.497 151.151 1.00 62.80  ? 203 PHE B CD1 1 
ATOM   4640 C  CD2 . PHE B 1 203 ? 99.600  143.384 149.993 1.00 63.61  ? 203 PHE B CD2 1 
ATOM   4641 C  CE1 . PHE B 1 203 ? 97.153  142.296 150.605 1.00 61.92  ? 203 PHE B CE1 1 
ATOM   4642 C  CE2 . PHE B 1 203 ? 99.228  142.180 149.446 1.00 64.63  ? 203 PHE B CE2 1 
ATOM   4643 C  CZ  . PHE B 1 203 ? 98.002  141.636 149.752 1.00 65.64  ? 203 PHE B CZ  1 
ATOM   4644 N  N   . MET B 1 204 ? 98.597  148.128 153.399 1.00 76.56  ? 204 MET B N   1 
ATOM   4645 C  CA  . MET B 1 204 ? 99.012  148.913 154.550 1.00 80.03  ? 204 MET B CA  1 
ATOM   4646 C  C   . MET B 1 204 ? 97.920  149.024 155.602 1.00 81.66  ? 204 MET B C   1 
ATOM   4647 O  O   . MET B 1 204 ? 98.081  149.777 156.567 1.00 82.72  ? 204 MET B O   1 
ATOM   4648 C  CB  . MET B 1 204 ? 99.464  150.304 154.105 1.00 81.40  ? 204 MET B CB  1 
ATOM   4649 C  CG  . MET B 1 204 ? 100.971 150.434 153.956 1.00 82.26  ? 204 MET B CG  1 
ATOM   4650 S  SD  . MET B 1 204 ? 101.465 151.718 152.793 1.00 93.84  ? 204 MET B SD  1 
ATOM   4651 C  CE  . MET B 1 204 ? 102.781 150.882 151.914 1.00 82.36  ? 204 MET B CE  1 
ATOM   4652 N  N   . HIS B 1 205 ? 96.807  148.308 155.425 1.00 82.51  ? 205 HIS B N   1 
ATOM   4653 C  CA  . HIS B 1 205 ? 95.818  148.202 156.491 1.00 85.77  ? 205 HIS B CA  1 
ATOM   4654 C  C   . HIS B 1 205 ? 96.352  147.394 157.667 1.00 87.97  ? 205 HIS B C   1 
ATOM   4655 O  O   . HIS B 1 205 ? 96.008  147.679 158.819 1.00 87.85  ? 205 HIS B O   1 
ATOM   4656 C  CB  . HIS B 1 205 ? 94.531  147.574 155.958 1.00 85.44  ? 205 HIS B CB  1 
ATOM   4657 C  CG  . HIS B 1 205 ? 94.539  146.076 155.969 1.00 86.35  ? 205 HIS B CG  1 
ATOM   4658 N  ND1 . HIS B 1 205 ? 95.317  145.329 155.110 1.00 83.36  ? 205 HIS B ND1 1 
ATOM   4659 C  CD2 . HIS B 1 205 ? 93.870  145.185 156.738 1.00 86.22  ? 205 HIS B CD2 1 
ATOM   4660 C  CE1 . HIS B 1 205 ? 95.121  144.044 155.346 1.00 82.79  ? 205 HIS B CE1 1 
ATOM   4661 N  NE2 . HIS B 1 205 ? 94.248  143.930 156.329 1.00 83.91  ? 205 HIS B NE2 1 
ATOM   4662 N  N   . LEU B 1 206 ? 97.184  146.385 157.398 1.00 86.13  ? 206 LEU B N   1 
ATOM   4663 C  CA  . LEU B 1 206 ? 97.748  145.584 158.478 1.00 84.80  ? 206 LEU B CA  1 
ATOM   4664 C  C   . LEU B 1 206 ? 98.849  146.326 159.221 1.00 87.46  ? 206 LEU B C   1 
ATOM   4665 O  O   . LEU B 1 206 ? 99.032  146.113 160.424 1.00 86.30  ? 206 LEU B O   1 
ATOM   4666 C  CB  . LEU B 1 206 ? 98.281  144.259 157.928 1.00 86.44  ? 206 LEU B CB  1 
ATOM   4667 C  CG  . LEU B 1 206 ? 99.489  144.276 156.984 1.00 84.17  ? 206 LEU B CG  1 
ATOM   4668 C  CD1 . LEU B 1 206 ? 100.803 144.089 157.727 1.00 83.90  ? 206 LEU B CD1 1 
ATOM   4669 C  CD2 . LEU B 1 206 ? 99.329  143.205 155.920 1.00 85.42  ? 206 LEU B CD2 1 
ATOM   4670 N  N   . LEU B 1 207 ? 99.577  147.195 158.537 1.00 105.52 ? 207 LEU B N   1 
ATOM   4671 C  CA  . LEU B 1 207 ? 100.778 147.798 159.100 1.00 106.90 ? 207 LEU B CA  1 
ATOM   4672 C  C   . LEU B 1 207 ? 100.358 148.905 160.060 1.00 107.71 ? 207 LEU B C   1 
ATOM   4673 O  O   . LEU B 1 207 ? 99.877  149.951 159.603 1.00 104.09 ? 207 LEU B O   1 
ATOM   4674 C  CB  . LEU B 1 207 ? 101.654 148.347 157.973 1.00 105.11 ? 207 LEU B CB  1 
ATOM   4675 C  CG  . LEU B 1 207 ? 103.095 148.831 158.193 1.00 106.40 ? 207 LEU B CG  1 
ATOM   4676 C  CD1 . LEU B 1 207 ? 103.706 149.266 156.861 1.00 105.50 ? 207 LEU B CD1 1 
ATOM   4677 C  CD2 . LEU B 1 207 ? 103.269 149.904 159.247 1.00 105.52 ? 207 LEU B CD2 1 
ATOM   4678 N  N   . PRO B 1 208 ? 100.523 148.736 161.374 1.00 122.77 ? 208 PRO B N   1 
ATOM   4679 C  CA  . PRO B 1 208 ? 99.973  149.718 162.320 1.00 122.73 ? 208 PRO B CA  1 
ATOM   4680 C  C   . PRO B 1 208 ? 100.741 151.030 162.412 1.00 122.67 ? 208 PRO B C   1 
ATOM   4681 O  O   . PRO B 1 208 ? 100.129 152.101 162.458 1.00 122.42 ? 208 PRO B O   1 
ATOM   4682 C  CB  . PRO B 1 208 ? 100.009 148.963 163.654 1.00 121.29 ? 208 PRO B CB  1 
ATOM   4683 C  CG  . PRO B 1 208 ? 101.149 148.011 163.514 1.00 120.57 ? 208 PRO B CG  1 
ATOM   4684 C  CD  . PRO B 1 208 ? 101.260 147.654 162.053 1.00 120.46 ? 208 PRO B CD  1 
ATOM   4685 N  N   . ASN B 1 209 ? 102.075 150.967 162.443 1.00 130.09 ? 209 ASN B N   1 
ATOM   4686 C  CA  . ASN B 1 209 ? 102.859 152.128 162.860 1.00 130.03 ? 209 ASN B CA  1 
ATOM   4687 C  C   . ASN B 1 209 ? 102.956 153.210 161.790 1.00 130.68 ? 209 ASN B C   1 
ATOM   4688 O  O   . ASN B 1 209 ? 102.933 154.400 162.125 1.00 129.45 ? 209 ASN B O   1 
ATOM   4689 C  CB  . ASN B 1 209 ? 104.260 151.690 163.295 1.00 128.82 ? 209 ASN B CB  1 
ATOM   4690 C  CG  . ASN B 1 209 ? 104.900 150.720 162.324 1.00 129.67 ? 209 ASN B CG  1 
ATOM   4691 O  OD1 . ASN B 1 209 ? 104.481 149.569 162.214 1.00 130.15 ? 209 ASN B OD1 1 
ATOM   4692 N  ND2 . ASN B 1 209 ? 105.927 151.179 161.620 1.00 129.70 ? 209 ASN B ND2 1 
ATOM   4693 N  N   . PHE B 1 210 ? 103.071 152.838 160.517 1.00 128.55 ? 210 PHE B N   1 
ATOM   4694 C  CA  . PHE B 1 210 ? 103.257 153.833 159.467 1.00 127.40 ? 210 PHE B CA  1 
ATOM   4695 C  C   . PHE B 1 210 ? 102.004 154.683 159.308 1.00 127.62 ? 210 PHE B C   1 
ATOM   4696 O  O   . PHE B 1 210 ? 100.882 154.168 159.319 1.00 128.46 ? 210 PHE B O   1 
ATOM   4697 C  CB  . PHE B 1 210 ? 103.606 153.158 158.140 1.00 127.14 ? 210 PHE B CB  1 
ATOM   4698 C  CG  . PHE B 1 210 ? 105.084 153.064 157.875 1.00 128.41 ? 210 PHE B CG  1 
ATOM   4699 C  CD1 . PHE B 1 210 ? 105.903 152.306 158.695 1.00 127.31 ? 210 PHE B CD1 1 
ATOM   4700 C  CD2 . PHE B 1 210 ? 105.654 153.730 156.802 1.00 128.08 ? 210 PHE B CD2 1 
ATOM   4701 C  CE1 . PHE B 1 210 ? 107.263 152.216 158.452 1.00 126.96 ? 210 PHE B CE1 1 
ATOM   4702 C  CE2 . PHE B 1 210 ? 107.012 153.643 156.554 1.00 126.63 ? 210 PHE B CE2 1 
ATOM   4703 C  CZ  . PHE B 1 210 ? 107.817 152.885 157.380 1.00 127.03 ? 210 PHE B CZ  1 
ATOM   4704 N  N   . ALA B 1 211 ? 102.200 155.994 159.161 1.00 125.77 ? 211 ALA B N   1 
ATOM   4705 C  CA  . ALA B 1 211 ? 101.114 156.943 158.958 1.00 125.53 ? 211 ALA B CA  1 
ATOM   4706 C  C   . ALA B 1 211 ? 101.080 157.481 157.532 1.00 126.11 ? 211 ALA B C   1 
ATOM   4707 O  O   . ALA B 1 211 ? 100.623 158.607 157.303 1.00 124.73 ? 211 ALA B O   1 
ATOM   4708 C  CB  . ALA B 1 211 ? 101.220 158.094 159.958 1.00 124.34 ? 211 ALA B CB  1 
ATOM   4709 N  N   . GLU B 1 212 ? 101.564 156.698 156.568 1.00 125.02 ? 212 GLU B N   1 
ATOM   4710 C  CA  . GLU B 1 212 ? 101.611 157.130 155.177 1.00 124.49 ? 212 GLU B CA  1 
ATOM   4711 C  C   . GLU B 1 212 ? 100.212 157.353 154.622 1.00 124.51 ? 212 GLU B C   1 
ATOM   4712 O  O   . GLU B 1 212 ? 99.450  156.398 154.435 1.00 124.80 ? 212 GLU B O   1 
ATOM   4713 C  CB  . GLU B 1 212 ? 102.357 156.104 154.324 1.00 123.52 ? 212 GLU B CB  1 
ATOM   4714 C  CG  . GLU B 1 212 ? 103.774 155.833 154.785 1.00 123.23 ? 212 GLU B CG  1 
ATOM   4715 C  CD  . GLU B 1 212 ? 104.644 155.278 153.680 1.00 123.88 ? 212 GLU B CD  1 
ATOM   4716 O  OE1 . GLU B 1 212 ? 104.301 154.208 153.136 1.00 122.95 ? 212 GLU B OE1 1 
ATOM   4717 O  OE2 . GLU B 1 212 ? 105.671 155.910 153.353 1.00 124.66 ? 212 GLU B OE2 1 
ATOM   4718 N  N   . CYS B 1 213 ? 99.872  158.609 154.348 1.00 119.04 ? 213 CYS B N   1 
ATOM   4719 C  CA  . CYS B 1 213 ? 98.561  158.933 153.814 1.00 119.85 ? 213 CYS B CA  1 
ATOM   4720 C  C   . CYS B 1 213 ? 98.413  158.373 152.401 1.00 118.51 ? 213 CYS B C   1 
ATOM   4721 O  O   . CYS B 1 213 ? 99.379  157.939 151.767 1.00 117.05 ? 213 CYS B O   1 
ATOM   4722 C  CB  . CYS B 1 213 ? 98.342  160.445 153.823 1.00 118.66 ? 213 CYS B CB  1 
ATOM   4723 S  SG  . CYS B 1 213 ? 96.670  160.959 153.370 1.00 117.10 ? 213 CYS B SG  1 
ATOM   4724 N  N   . TRP B 1 214 ? 97.172  158.378 151.907 1.00 117.12 ? 214 TRP B N   1 
ATOM   4725 C  CA  . TRP B 1 214 ? 96.902  157.777 150.606 1.00 116.81 ? 214 TRP B CA  1 
ATOM   4726 C  C   . TRP B 1 214 ? 97.626  158.508 149.485 1.00 115.84 ? 214 TRP B C   1 
ATOM   4727 O  O   . TRP B 1 214 ? 98.027  157.881 148.499 1.00 114.69 ? 214 TRP B O   1 
ATOM   4728 C  CB  . TRP B 1 214 ? 95.398  157.746 150.331 1.00 117.24 ? 214 TRP B CB  1 
ATOM   4729 C  CG  . TRP B 1 214 ? 94.681  159.011 150.688 1.00 117.94 ? 214 TRP B CG  1 
ATOM   4730 C  CD1 . TRP B 1 214 ? 94.133  159.329 151.896 1.00 117.04 ? 214 TRP B CD1 1 
ATOM   4731 C  CD2 . TRP B 1 214 ? 94.426  160.125 149.826 1.00 118.51 ? 214 TRP B CD2 1 
ATOM   4732 N  NE1 . TRP B 1 214 ? 93.556  160.574 151.840 1.00 117.66 ? 214 TRP B NE1 1 
ATOM   4733 C  CE2 . TRP B 1 214 ? 93.722  161.084 150.580 1.00 118.88 ? 214 TRP B CE2 1 
ATOM   4734 C  CE3 . TRP B 1 214 ? 94.726  160.405 148.490 1.00 117.68 ? 214 TRP B CE3 1 
ATOM   4735 C  CZ2 . TRP B 1 214 ? 93.313  162.302 150.044 1.00 117.06 ? 214 TRP B CZ2 1 
ATOM   4736 C  CZ3 . TRP B 1 214 ? 94.319  161.616 147.959 1.00 117.35 ? 214 TRP B CZ3 1 
ATOM   4737 C  CH2 . TRP B 1 214 ? 93.620  162.549 148.735 1.00 116.23 ? 214 TRP B CH2 1 
ATOM   4738 N  N   . TRP B 1 215 ? 97.815  159.823 149.617 1.00 113.68 ? 215 TRP B N   1 
ATOM   4739 C  CA  . TRP B 1 215 ? 98.492  160.579 148.569 1.00 114.27 ? 215 TRP B CA  1 
ATOM   4740 C  C   . TRP B 1 215 ? 99.932  160.131 148.366 1.00 114.23 ? 215 TRP B C   1 
ATOM   4741 O  O   . TRP B 1 215 ? 100.504 160.392 147.302 1.00 113.40 ? 215 TRP B O   1 
ATOM   4742 C  CB  . TRP B 1 215 ? 98.449  162.078 148.880 1.00 113.83 ? 215 TRP B CB  1 
ATOM   4743 C  CG  . TRP B 1 215 ? 99.238  162.492 150.091 1.00 114.49 ? 215 TRP B CG  1 
ATOM   4744 C  CD1 . TRP B 1 215 ? 98.744  162.746 151.336 1.00 115.15 ? 215 TRP B CD1 1 
ATOM   4745 C  CD2 . TRP B 1 215 ? 100.654 162.717 150.170 1.00 114.61 ? 215 TRP B CD2 1 
ATOM   4746 N  NE1 . TRP B 1 215 ? 99.760  163.104 152.187 1.00 115.04 ? 215 TRP B NE1 1 
ATOM   4747 C  CE2 . TRP B 1 215 ? 100.942 163.095 151.496 1.00 114.72 ? 215 TRP B CE2 1 
ATOM   4748 C  CE3 . TRP B 1 215 ? 101.704 162.631 149.250 1.00 113.96 ? 215 TRP B CE3 1 
ATOM   4749 C  CZ2 . TRP B 1 215 ? 102.235 163.385 151.924 1.00 114.56 ? 215 TRP B CZ2 1 
ATOM   4750 C  CZ3 . TRP B 1 215 ? 102.986 162.917 149.678 1.00 115.26 ? 215 TRP B CZ3 1 
ATOM   4751 C  CH2 . TRP B 1 215 ? 103.240 163.291 151.002 1.00 115.42 ? 215 TRP B CH2 1 
ATOM   4752 N  N   . ASP B 1 216 ? 100.534 159.471 149.359 1.00 108.65 ? 216 ASP B N   1 
ATOM   4753 C  CA  . ASP B 1 216 ? 101.917 159.029 149.221 1.00 107.79 ? 216 ASP B CA  1 
ATOM   4754 C  C   . ASP B 1 216 ? 102.068 158.017 148.093 1.00 106.95 ? 216 ASP B C   1 
ATOM   4755 O  O   . ASP B 1 216 ? 103.035 158.072 147.327 1.00 106.69 ? 216 ASP B O   1 
ATOM   4756 C  CB  . ASP B 1 216 ? 102.415 158.434 150.536 1.00 108.85 ? 216 ASP B CB  1 
ATOM   4757 C  CG  . ASP B 1 216 ? 103.844 157.933 150.443 1.00 108.55 ? 216 ASP B CG  1 
ATOM   4758 O  OD1 . ASP B 1 216 ? 104.629 158.506 149.660 1.00 106.56 ? 216 ASP B OD1 1 
ATOM   4759 O  OD2 . ASP B 1 216 ? 104.182 156.961 151.151 1.00 109.64 ? 216 ASP B OD2 1 
ATOM   4760 N  N   . GLN B 1 217 ? 101.126 157.080 147.976 1.00 94.03  ? 217 GLN B N   1 
ATOM   4761 C  CA  . GLN B 1 217 ? 101.207 156.033 146.965 1.00 94.14  ? 217 GLN B CA  1 
ATOM   4762 C  C   . GLN B 1 217 ? 100.038 156.076 145.989 1.00 93.77  ? 217 GLN B C   1 
ATOM   4763 O  O   . GLN B 1 217 ? 99.780  155.091 145.293 1.00 91.91  ? 217 GLN B O   1 
ATOM   4764 C  CB  . GLN B 1 217 ? 101.303 154.656 147.624 1.00 92.07  ? 217 GLN B CB  1 
ATOM   4765 C  CG  . GLN B 1 217 ? 102.478 154.525 148.570 1.00 93.41  ? 217 GLN B CG  1 
ATOM   4766 C  CD  . GLN B 1 217 ? 103.069 153.138 148.557 1.00 92.71  ? 217 GLN B CD  1 
ATOM   4767 O  OE1 . GLN B 1 217 ? 102.594 152.263 147.839 1.00 89.32  ? 217 GLN B OE1 1 
ATOM   4768 N  NE2 . GLN B 1 217 ? 104.118 152.931 149.344 1.00 92.45  ? 217 GLN B NE2 1 
ATOM   4769 N  N   . VAL B 1 218 ? 99.318  157.193 145.933 1.00 100.26 ? 218 VAL B N   1 
ATOM   4770 C  CA  . VAL B 1 218 ? 98.314  157.408 144.894 1.00 101.34 ? 218 VAL B CA  1 
ATOM   4771 C  C   . VAL B 1 218 ? 98.531  158.699 144.122 1.00 98.98  ? 218 VAL B C   1 
ATOM   4772 O  O   . VAL B 1 218 ? 98.098  158.806 142.960 1.00 99.96  ? 218 VAL B O   1 
ATOM   4773 C  CB  . VAL B 1 218 ? 96.891  157.370 145.503 1.00 101.44 ? 218 VAL B CB  1 
ATOM   4774 C  CG1 . VAL B 1 218 ? 95.820  157.513 144.431 1.00 100.11 ? 218 VAL B CG1 1 
ATOM   4775 C  CG2 . VAL B 1 218 ? 96.680  156.074 146.264 1.00 100.04 ? 218 VAL B CG2 1 
ATOM   4776 N  N   . ILE B 1 219 ? 99.220  159.693 144.682 1.00 97.16  ? 219 ILE B N   1 
ATOM   4777 C  CA  . ILE B 1 219 ? 99.527  160.928 143.980 1.00 100.21 ? 219 ILE B CA  1 
ATOM   4778 C  C   . ILE B 1 219 ? 101.027 161.121 143.805 1.00 100.92 ? 219 ILE B C   1 
ATOM   4779 O  O   . ILE B 1 219 ? 101.484 161.510 142.725 1.00 101.75 ? 219 ILE B O   1 
ATOM   4780 C  CB  . ILE B 1 219 ? 98.903  162.144 144.698 1.00 101.09 ? 219 ILE B CB  1 
ATOM   4781 C  CG1 . ILE B 1 219 ? 97.422  161.885 144.983 1.00 99.56  ? 219 ILE B CG1 1 
ATOM   4782 C  CG2 . ILE B 1 219 ? 99.077  163.406 143.866 1.00 98.05  ? 219 ILE B CG2 1 
ATOM   4783 C  CD1 . ILE B 1 219 ? 96.700  163.062 145.594 1.00 101.10 ? 219 ILE B CD1 1 
ATOM   4784 N  N   . LEU B 1 220 ? 101.813 160.855 144.850 1.00 97.42  ? 220 LEU B N   1 
ATOM   4785 C  CA  . LEU B 1 220 ? 103.261 161.002 144.736 1.00 97.07  ? 220 LEU B CA  1 
ATOM   4786 C  C   . LEU B 1 220 ? 103.874 159.861 143.933 1.00 96.42  ? 220 LEU B C   1 
ATOM   4787 O  O   . LEU B 1 220 ? 104.787 160.081 143.131 1.00 96.06  ? 220 LEU B O   1 
ATOM   4788 C  CB  . LEU B 1 220 ? 103.893 161.086 146.127 1.00 98.72  ? 220 LEU B CB  1 
ATOM   4789 C  CG  . LEU B 1 220 ? 105.422 161.054 146.247 1.00 98.95  ? 220 LEU B CG  1 
ATOM   4790 C  CD1 . LEU B 1 220 ? 105.887 162.023 147.318 1.00 98.55  ? 220 LEU B CD1 1 
ATOM   4791 C  CD2 . LEU B 1 220 ? 105.930 159.654 146.560 1.00 97.59  ? 220 LEU B CD2 1 
ATOM   4792 N  N   . ASP B 1 221 ? 103.390 158.637 144.136 1.00 87.87  ? 221 ASP B N   1 
ATOM   4793 C  CA  . ASP B 1 221 ? 103.991 157.469 143.505 1.00 85.00  ? 221 ASP B CA  1 
ATOM   4794 C  C   . ASP B 1 221 ? 103.434 157.210 142.110 1.00 85.42  ? 221 ASP B C   1 
ATOM   4795 O  O   . ASP B 1 221 ? 104.201 157.079 141.154 1.00 86.18  ? 221 ASP B O   1 
ATOM   4796 C  CB  . ASP B 1 221 ? 103.788 156.233 144.383 1.00 84.85  ? 221 ASP B CB  1 
ATOM   4797 C  CG  . ASP B 1 221 ? 104.987 155.937 145.252 1.00 86.35  ? 221 ASP B CG  1 
ATOM   4798 O  OD1 . ASP B 1 221 ? 106.067 155.652 144.696 1.00 85.95  ? 221 ASP B OD1 1 
ATOM   4799 O  OD2 . ASP B 1 221 ? 104.850 155.990 146.492 1.00 87.05  ? 221 ASP B OD2 1 
ATOM   4800 N  N   . ILE B 1 222 ? 102.109 157.135 141.980 1.00 83.33  ? 222 ILE B N   1 
ATOM   4801 C  CA  . ILE B 1 222 ? 101.506 156.802 140.691 1.00 83.87  ? 222 ILE B CA  1 
ATOM   4802 C  C   . ILE B 1 222 ? 101.858 157.853 139.646 1.00 82.14  ? 222 ILE B C   1 
ATOM   4803 O  O   . ILE B 1 222 ? 102.218 157.523 138.510 1.00 82.24  ? 222 ILE B O   1 
ATOM   4804 C  CB  . ILE B 1 222 ? 99.982  156.640 140.841 1.00 81.86  ? 222 ILE B CB  1 
ATOM   4805 C  CG1 . ILE B 1 222 ? 99.645  155.289 141.464 1.00 77.89  ? 222 ILE B CG1 1 
ATOM   4806 C  CG2 . ILE B 1 222 ? 99.293  156.767 139.498 1.00 80.43  ? 222 ILE B CG2 1 
ATOM   4807 C  CD1 . ILE B 1 222 ? 98.174  154.969 141.443 1.00 76.30  ? 222 ILE B CD1 1 
ATOM   4808 N  N   . LEU B 1 223 ? 101.780 159.130 140.015 1.00 78.30  ? 223 LEU B N   1 
ATOM   4809 C  CA  . LEU B 1 223 ? 101.984 160.199 139.044 1.00 78.81  ? 223 LEU B CA  1 
ATOM   4810 C  C   . LEU B 1 223 ? 103.464 160.477 138.802 1.00 80.40  ? 223 LEU B C   1 
ATOM   4811 O  O   . LEU B 1 223 ? 103.950 160.362 137.674 1.00 84.19  ? 223 LEU B O   1 
ATOM   4812 C  CB  . LEU B 1 223 ? 101.269 161.474 139.501 1.00 80.27  ? 223 LEU B CB  1 
ATOM   4813 C  CG  . LEU B 1 223 ? 99.776  161.666 139.209 1.00 82.46  ? 223 LEU B CG  1 
ATOM   4814 C  CD1 . LEU B 1 223 ? 98.989  160.368 139.260 1.00 79.94  ? 223 LEU B CD1 1 
ATOM   4815 C  CD2 . LEU B 1 223 ? 99.185  162.686 140.173 1.00 81.13  ? 223 LEU B CD2 1 
ATOM   4816 N  N   . LEU B 1 224 ? 104.197 160.851 139.849 1.00 77.62  ? 224 LEU B N   1 
ATOM   4817 C  CA  . LEU B 1 224 ? 105.542 161.390 139.662 1.00 79.33  ? 224 LEU B CA  1 
ATOM   4818 C  C   . LEU B 1 224 ? 106.610 160.300 139.594 1.00 76.29  ? 224 LEU B C   1 
ATOM   4819 O  O   . LEU B 1 224 ? 107.330 160.194 138.597 1.00 76.11  ? 224 LEU B O   1 
ATOM   4820 C  CB  . LEU B 1 224 ? 105.865 162.386 140.780 1.00 80.13  ? 224 LEU B CB  1 
ATOM   4821 C  CG  . LEU B 1 224 ? 105.556 163.854 140.481 1.00 78.65  ? 224 LEU B CG  1 
ATOM   4822 C  CD1 . LEU B 1 224 ? 104.078 164.148 140.666 1.00 77.97  ? 224 LEU B CD1 1 
ATOM   4823 C  CD2 . LEU B 1 224 ? 106.398 164.764 141.357 1.00 78.30  ? 224 LEU B CD2 1 
ATOM   4824 N  N   . CYS B 1 225 ? 106.736 159.495 140.649 1.00 76.73  ? 225 CYS B N   1 
ATOM   4825 C  CA  . CYS B 1 225 ? 107.802 158.499 140.684 1.00 75.96  ? 225 CYS B CA  1 
ATOM   4826 C  C   . CYS B 1 225 ? 107.614 157.439 139.605 1.00 75.75  ? 225 CYS B C   1 
ATOM   4827 O  O   . CYS B 1 225 ? 108.584 157.019 138.966 1.00 76.71  ? 225 CYS B O   1 
ATOM   4828 C  CB  . CYS B 1 225 ? 107.875 157.853 142.067 1.00 78.13  ? 225 CYS B CB  1 
ATOM   4829 S  SG  . CYS B 1 225 ? 107.830 159.022 143.444 1.00 84.02  ? 225 CYS B SG  1 
ATOM   4830 N  N   . ASN B 1 226 ? 106.379 156.991 139.388 1.00 66.93  ? 226 ASN B N   1 
ATOM   4831 C  CA  . ASN B 1 226 ? 106.109 155.985 138.366 1.00 65.19  ? 226 ASN B CA  1 
ATOM   4832 C  C   . ASN B 1 226 ? 105.899 156.621 136.994 1.00 66.25  ? 226 ASN B C   1 
ATOM   4833 O  O   . ASN B 1 226 ? 106.626 156.314 136.046 1.00 69.43  ? 226 ASN B O   1 
ATOM   4834 C  CB  . ASN B 1 226 ? 104.890 155.146 138.762 1.00 67.28  ? 226 ASN B CB  1 
ATOM   4835 C  CG  . ASN B 1 226 ? 105.095 154.399 140.062 1.00 68.41  ? 226 ASN B CG  1 
ATOM   4836 O  OD1 . ASN B 1 226 ? 106.132 154.530 140.709 1.00 66.81  ? 226 ASN B OD1 1 
ATOM   4837 N  ND2 . ASN B 1 226 ? 104.104 153.612 140.452 1.00 65.93  ? 226 ASN B ND2 1 
ATOM   4838 N  N   . GLY B 1 227 ? 104.914 157.512 136.881 1.00 63.00  ? 227 GLY B N   1 
ATOM   4839 C  CA  . GLY B 1 227 ? 104.623 158.121 135.594 1.00 59.75  ? 227 GLY B CA  1 
ATOM   4840 C  C   . GLY B 1 227 ? 105.788 158.916 135.041 1.00 59.55  ? 227 GLY B C   1 
ATOM   4841 O  O   . GLY B 1 227 ? 105.998 158.966 133.828 1.00 63.48  ? 227 GLY B O   1 
ATOM   4842 N  N   . GLY B 1 228 ? 106.551 159.566 135.920 1.00 52.93  ? 228 GLY B N   1 
ATOM   4843 C  CA  . GLY B 1 228 ? 107.772 160.213 135.474 1.00 54.79  ? 228 GLY B CA  1 
ATOM   4844 C  C   . GLY B 1 228 ? 108.812 159.212 135.012 1.00 56.57  ? 228 GLY B C   1 
ATOM   4845 O  O   . GLY B 1 228 ? 109.518 159.444 134.028 1.00 58.69  ? 228 GLY B O   1 
ATOM   4846 N  N   . GLY B 1 229 ? 108.931 158.091 135.723 1.00 59.98  ? 229 GLY B N   1 
ATOM   4847 C  CA  . GLY B 1 229 ? 109.812 157.031 135.268 1.00 56.49  ? 229 GLY B CA  1 
ATOM   4848 C  C   . GLY B 1 229 ? 109.329 156.380 133.988 1.00 58.39  ? 229 GLY B C   1 
ATOM   4849 O  O   . GLY B 1 229 ? 110.116 156.140 133.071 1.00 60.92  ? 229 GLY B O   1 
ATOM   4850 N  N   . ILE B 1 230 ? 108.028 156.091 133.905 1.00 56.03  ? 230 ILE B N   1 
ATOM   4851 C  CA  . ILE B 1 230 ? 107.480 155.444 132.716 1.00 48.17  ? 230 ILE B CA  1 
ATOM   4852 C  C   . ILE B 1 230 ? 107.655 156.337 131.498 1.00 55.55  ? 230 ILE B C   1 
ATOM   4853 O  O   . ILE B 1 230 ? 107.984 155.864 130.404 1.00 63.75  ? 230 ILE B O   1 
ATOM   4854 C  CB  . ILE B 1 230 ? 106.001 155.078 132.938 1.00 46.31  ? 230 ILE B CB  1 
ATOM   4855 C  CG1 . ILE B 1 230 ? 105.863 154.030 134.034 1.00 44.50  ? 230 ILE B CG1 1 
ATOM   4856 C  CG2 . ILE B 1 230 ? 105.379 154.555 131.662 1.00 54.00  ? 230 ILE B CG2 1 
ATOM   4857 C  CD1 . ILE B 1 230 ? 104.437 153.718 134.373 1.00 48.32  ? 230 ILE B CD1 1 
ATOM   4858 N  N   . TRP B 1 231 ? 107.432 157.640 131.664 1.00 52.46  ? 231 TRP B N   1 
ATOM   4859 C  CA  . TRP B 1 231 ? 107.585 158.572 130.553 1.00 50.52  ? 231 TRP B CA  1 
ATOM   4860 C  C   . TRP B 1 231 ? 109.022 158.604 130.054 1.00 54.11  ? 231 TRP B C   1 
ATOM   4861 O  O   . TRP B 1 231 ? 109.272 158.543 128.846 1.00 58.39  ? 231 TRP B O   1 
ATOM   4862 C  CB  . TRP B 1 231 ? 107.138 159.966 130.985 1.00 55.37  ? 231 TRP B CB  1 
ATOM   4863 C  CG  . TRP B 1 231 ? 106.970 160.935 129.862 1.00 58.93  ? 231 TRP B CG  1 
ATOM   4864 C  CD1 . TRP B 1 231 ? 106.943 160.652 128.530 1.00 59.70  ? 231 TRP B CD1 1 
ATOM   4865 C  CD2 . TRP B 1 231 ? 106.798 162.350 129.977 1.00 56.64  ? 231 TRP B CD2 1 
ATOM   4866 N  NE1 . TRP B 1 231 ? 106.766 161.804 127.807 1.00 55.48  ? 231 TRP B NE1 1 
ATOM   4867 C  CE2 . TRP B 1 231 ? 106.674 162.862 128.673 1.00 56.72  ? 231 TRP B CE2 1 
ATOM   4868 C  CE3 . TRP B 1 231 ? 106.735 163.235 131.058 1.00 57.35  ? 231 TRP B CE3 1 
ATOM   4869 C  CZ2 . TRP B 1 231 ? 106.493 164.218 128.419 1.00 61.81  ? 231 TRP B CZ2 1 
ATOM   4870 C  CZ3 . TRP B 1 231 ? 106.555 164.579 130.804 1.00 58.18  ? 231 TRP B CZ3 1 
ATOM   4871 C  CH2 . TRP B 1 231 ? 106.437 165.058 129.496 1.00 61.75  ? 231 TRP B CH2 1 
ATOM   4872 N  N   . LEU B 1 232 ? 109.983 158.702 130.973 1.00 55.69  ? 232 LEU B N   1 
ATOM   4873 C  CA  . LEU B 1 232 ? 111.383 158.777 130.571 1.00 55.22  ? 232 LEU B CA  1 
ATOM   4874 C  C   . LEU B 1 232 ? 111.840 157.490 129.901 1.00 51.89  ? 232 LEU B C   1 
ATOM   4875 O  O   . LEU B 1 232 ? 112.594 157.527 128.924 1.00 57.68  ? 232 LEU B O   1 
ATOM   4876 C  CB  . LEU B 1 232 ? 112.263 159.087 131.778 1.00 57.59  ? 232 LEU B CB  1 
ATOM   4877 C  CG  . LEU B 1 232 ? 113.744 159.236 131.444 1.00 56.09  ? 232 LEU B CG  1 
ATOM   4878 C  CD1 . LEU B 1 232 ? 113.987 160.562 130.752 1.00 56.45  ? 232 LEU B CD1 1 
ATOM   4879 C  CD2 . LEU B 1 232 ? 114.599 159.104 132.690 1.00 55.59  ? 232 LEU B CD2 1 
ATOM   4880 N  N   . GLY B 1 233 ? 111.409 156.343 130.419 1.00 49.72  ? 233 GLY B N   1 
ATOM   4881 C  CA  . GLY B 1 233 ? 111.793 155.084 129.808 1.00 47.44  ? 233 GLY B CA  1 
ATOM   4882 C  C   . GLY B 1 233 ? 111.231 154.920 128.411 1.00 53.73  ? 233 GLY B C   1 
ATOM   4883 O  O   . GLY B 1 233 ? 111.927 154.466 127.503 1.00 57.37  ? 233 GLY B O   1 
ATOM   4884 N  N   . MET B 1 234 ? 109.965 155.290 128.219 1.00 59.15  ? 234 MET B N   1 
ATOM   4885 C  CA  . MET B 1 234 ? 109.344 155.152 126.908 1.00 58.12  ? 234 MET B CA  1 
ATOM   4886 C  C   . MET B 1 234 ? 109.828 156.211 125.927 1.00 58.93  ? 234 MET B C   1 
ATOM   4887 O  O   . MET B 1 234 ? 109.719 156.010 124.714 1.00 62.06  ? 234 MET B O   1 
ATOM   4888 C  CB  . MET B 1 234 ? 107.824 155.218 127.039 1.00 53.10  ? 234 MET B CB  1 
ATOM   4889 C  CG  . MET B 1 234 ? 107.218 153.996 127.690 1.00 52.03  ? 234 MET B CG  1 
ATOM   4890 S  SD  . MET B 1 234 ? 106.707 152.746 126.508 1.00 69.74  ? 234 MET B SD  1 
ATOM   4891 C  CE  . MET B 1 234 ? 106.135 153.769 125.163 1.00 61.49  ? 234 MET B CE  1 
ATOM   4892 N  N   . VAL B 1 235 ? 110.340 157.337 126.423 1.00 56.90  ? 235 VAL B N   1 
ATOM   4893 C  CA  . VAL B 1 235 ? 110.933 158.337 125.541 1.00 58.18  ? 235 VAL B CA  1 
ATOM   4894 C  C   . VAL B 1 235 ? 112.250 157.829 124.970 1.00 61.33  ? 235 VAL B C   1 
ATOM   4895 O  O   . VAL B 1 235 ? 112.566 158.062 123.797 1.00 68.02  ? 235 VAL B O   1 
ATOM   4896 C  CB  . VAL B 1 235 ? 111.108 159.668 126.293 1.00 56.26  ? 235 VAL B CB  1 
ATOM   4897 C  CG1 . VAL B 1 235 ? 112.221 160.494 125.679 1.00 55.87  ? 235 VAL B CG1 1 
ATOM   4898 C  CG2 . VAL B 1 235 ? 109.806 160.444 126.285 1.00 59.46  ? 235 VAL B CG2 1 
ATOM   4899 N  N   . VAL B 1 236 ? 113.036 157.125 125.784 1.00 56.06  ? 236 VAL B N   1 
ATOM   4900 C  CA  . VAL B 1 236 ? 114.308 156.586 125.316 1.00 51.08  ? 236 VAL B CA  1 
ATOM   4901 C  C   . VAL B 1 236 ? 114.084 155.472 124.298 1.00 57.80  ? 236 VAL B C   1 
ATOM   4902 O  O   . VAL B 1 236 ? 114.841 155.344 123.330 1.00 65.62  ? 236 VAL B O   1 
ATOM   4903 C  CB  . VAL B 1 236 ? 115.152 156.112 126.511 1.00 49.58  ? 236 VAL B CB  1 
ATOM   4904 C  CG1 . VAL B 1 236 ? 116.427 155.461 126.037 1.00 53.96  ? 236 VAL B CG1 1 
ATOM   4905 C  CG2 . VAL B 1 236 ? 115.474 157.283 127.409 1.00 51.52  ? 236 VAL B CG2 1 
ATOM   4906 N  N   . CYS B 1 237 ? 113.045 154.652 124.490 1.00 60.42  ? 237 CYS B N   1 
ATOM   4907 C  CA  . CYS B 1 237 ? 112.766 153.581 123.535 1.00 59.22  ? 237 CYS B CA  1 
ATOM   4908 C  C   . CYS B 1 237 ? 112.540 154.132 122.137 1.00 65.98  ? 237 CYS B C   1 
ATOM   4909 O  O   . CYS B 1 237 ? 112.987 153.541 121.149 1.00 70.08  ? 237 CYS B O   1 
ATOM   4910 C  CB  . CYS B 1 237 ? 111.546 152.777 123.966 1.00 61.32  ? 237 CYS B CB  1 
ATOM   4911 S  SG  . CYS B 1 237 ? 111.662 152.071 125.586 1.00 80.83  ? 237 CYS B SG  1 
ATOM   4912 N  N   . ARG B 1 238 ? 111.825 155.252 122.032 1.00 65.86  ? 238 ARG B N   1 
ATOM   4913 C  CA  . ARG B 1 238 ? 111.678 155.903 120.738 1.00 67.31  ? 238 ARG B CA  1 
ATOM   4914 C  C   . ARG B 1 238 ? 113.036 156.298 120.179 1.00 68.74  ? 238 ARG B C   1 
ATOM   4915 O  O   . ARG B 1 238 ? 113.314 156.092 118.994 1.00 72.20  ? 238 ARG B O   1 
ATOM   4916 C  CB  . ARG B 1 238 ? 110.775 157.127 120.869 1.00 69.59  ? 238 ARG B CB  1 
ATOM   4917 C  CG  . ARG B 1 238 ? 109.889 157.381 119.666 1.00 72.87  ? 238 ARG B CG  1 
ATOM   4918 C  CD  . ARG B 1 238 ? 108.492 156.822 119.878 1.00 72.24  ? 238 ARG B CD  1 
ATOM   4919 N  NE  . ARG B 1 238 ? 107.983 157.098 121.217 1.00 75.51  ? 238 ARG B NE  1 
ATOM   4920 C  CZ  . ARG B 1 238 ? 107.606 158.294 121.651 1.00 74.05  ? 238 ARG B CZ  1 
ATOM   4921 N  NH1 . ARG B 1 238 ? 107.658 159.361 120.872 1.00 72.07  ? 238 ARG B NH1 1 
ATOM   4922 N  NH2 . ARG B 1 238 ? 107.161 158.421 122.898 1.00 70.41  ? 238 ARG B NH2 1 
ATOM   4923 N  N   . PHE B 1 239 ? 113.903 156.849 121.027 1.00 60.52  ? 239 PHE B N   1 
ATOM   4924 C  CA  . PHE B 1 239 ? 115.227 157.257 120.575 1.00 61.45  ? 239 PHE B CA  1 
ATOM   4925 C  C   . PHE B 1 239 ? 116.107 156.049 120.270 1.00 63.16  ? 239 PHE B C   1 
ATOM   4926 O  O   . PHE B 1 239 ? 116.794 156.013 119.244 1.00 68.13  ? 239 PHE B O   1 
ATOM   4927 C  CB  . PHE B 1 239 ? 115.875 158.149 121.632 1.00 56.04  ? 239 PHE B CB  1 
ATOM   4928 C  CG  . PHE B 1 239 ? 117.265 158.576 121.291 1.00 61.17  ? 239 PHE B CG  1 
ATOM   4929 C  CD1 . PHE B 1 239 ? 117.504 159.387 120.198 1.00 63.49  ? 239 PHE B CD1 1 
ATOM   4930 C  CD2 . PHE B 1 239 ? 118.335 158.168 122.064 1.00 62.82  ? 239 PHE B CD2 1 
ATOM   4931 C  CE1 . PHE B 1 239 ? 118.785 159.783 119.880 1.00 63.34  ? 239 PHE B CE1 1 
ATOM   4932 C  CE2 . PHE B 1 239 ? 119.618 158.561 121.753 1.00 65.81  ? 239 PHE B CE2 1 
ATOM   4933 C  CZ  . PHE B 1 239 ? 119.843 159.370 120.659 1.00 67.21  ? 239 PHE B CZ  1 
ATOM   4934 N  N   . LEU B 1 240 ? 116.091 155.044 121.147 1.00 56.29  ? 240 LEU B N   1 
ATOM   4935 C  CA  . LEU B 1 240 ? 116.992 153.909 120.986 1.00 52.01  ? 240 LEU B CA  1 
ATOM   4936 C  C   . LEU B 1 240 ? 116.599 153.024 119.812 1.00 53.16  ? 240 LEU B C   1 
ATOM   4937 O  O   . LEU B 1 240 ? 117.455 152.339 119.245 1.00 55.48  ? 240 LEU B O   1 
ATOM   4938 C  CB  . LEU B 1 240 ? 117.029 153.081 122.267 1.00 50.63  ? 240 LEU B CB  1 
ATOM   4939 C  CG  . LEU B 1 240 ? 118.049 153.488 123.324 1.00 47.67  ? 240 LEU B CG  1 
ATOM   4940 C  CD1 . LEU B 1 240 ? 117.986 152.531 124.492 1.00 48.76  ? 240 LEU B CD1 1 
ATOM   4941 C  CD2 . LEU B 1 240 ? 119.438 153.514 122.730 1.00 50.83  ? 240 LEU B CD2 1 
ATOM   4942 N  N   . GLU B 1 241 ? 115.322 153.006 119.439 1.00 60.35  ? 241 GLU B N   1 
ATOM   4943 C  CA  . GLU B 1 241 ? 114.880 152.124 118.368 1.00 66.05  ? 241 GLU B CA  1 
ATOM   4944 C  C   . GLU B 1 241 ? 114.844 152.803 117.008 1.00 68.60  ? 241 GLU B C   1 
ATOM   4945 O  O   . GLU B 1 241 ? 114.811 152.107 115.989 1.00 72.10  ? 241 GLU B O   1 
ATOM   4946 C  CB  . GLU B 1 241 ? 113.499 151.546 118.691 1.00 65.98  ? 241 GLU B CB  1 
ATOM   4947 C  CG  . GLU B 1 241 ? 112.336 152.350 118.156 1.00 64.60  ? 241 GLU B CG  1 
ATOM   4948 C  CD  . GLU B 1 241 ? 111.004 151.786 118.590 1.00 65.64  ? 241 GLU B CD  1 
ATOM   4949 O  OE1 . GLU B 1 241 ? 110.999 150.817 119.375 1.00 66.90  ? 241 GLU B OE1 1 
ATOM   4950 O  OE2 . GLU B 1 241 ? 109.962 152.308 118.145 1.00 66.85  ? 241 GLU B OE2 1 
ATOM   4951 N  N   . MET B 1 242 ? 114.849 154.133 116.965 1.00 69.70  ? 242 MET B N   1 
ATOM   4952 C  CA  . MET B 1 242 ? 114.952 154.871 115.714 1.00 69.89  ? 242 MET B CA  1 
ATOM   4953 C  C   . MET B 1 242 ? 116.381 155.278 115.394 1.00 73.56  ? 242 MET B C   1 
ATOM   4954 O  O   . MET B 1 242 ? 116.606 155.980 114.404 1.00 75.49  ? 242 MET B O   1 
ATOM   4955 C  CB  . MET B 1 242 ? 114.060 156.114 115.753 1.00 68.89  ? 242 MET B CB  1 
ATOM   4956 C  CG  . MET B 1 242 ? 112.704 155.917 115.105 1.00 73.51  ? 242 MET B CG  1 
ATOM   4957 S  SD  . MET B 1 242 ? 111.640 157.370 115.212 1.00 86.11  ? 242 MET B SD  1 
ATOM   4958 C  CE  . MET B 1 242 ? 112.171 158.091 116.760 1.00 71.30  ? 242 MET B CE  1 
ATOM   4959 N  N   . ARG B 1 243 ? 117.345 154.856 116.205 1.00 65.92  ? 243 ARG B N   1 
ATOM   4960 C  CA  . ARG B 1 243 ? 118.737 155.230 116.009 1.00 62.17  ? 243 ARG B CA  1 
ATOM   4961 C  C   . ARG B 1 243 ? 119.393 154.331 114.972 1.00 66.21  ? 243 ARG B C   1 
ATOM   4962 O  O   . ARG B 1 243 ? 119.118 153.130 114.906 1.00 68.47  ? 243 ARG B O   1 
ATOM   4963 C  CB  . ARG B 1 243 ? 119.493 155.145 117.334 1.00 59.41  ? 243 ARG B CB  1 
ATOM   4964 C  CG  . ARG B 1 243 ? 120.987 155.338 117.217 1.00 62.80  ? 243 ARG B CG  1 
ATOM   4965 C  CD  . ARG B 1 243 ? 121.549 156.035 118.433 1.00 62.30  ? 243 ARG B CD  1 
ATOM   4966 N  NE  . ARG B 1 243 ? 121.970 155.085 119.453 1.00 65.12  ? 243 ARG B NE  1 
ATOM   4967 C  CZ  . ARG B 1 243 ? 123.231 154.747 119.684 1.00 67.72  ? 243 ARG B CZ  1 
ATOM   4968 N  NH1 . ARG B 1 243 ? 124.223 155.248 118.967 1.00 65.00  ? 243 ARG B NH1 1 
ATOM   4969 N  NH2 . ARG B 1 243 ? 123.504 153.885 120.659 1.00 66.49  ? 243 ARG B NH2 1 
ATOM   4970 N  N   . THR B 1 244 ? 120.257 154.923 114.150 1.00 66.88  ? 244 THR B N   1 
ATOM   4971 C  CA  . THR B 1 244 ? 121.053 154.179 113.181 1.00 66.40  ? 244 THR B CA  1 
ATOM   4972 C  C   . THR B 1 244 ? 122.335 153.728 113.870 1.00 67.47  ? 244 THR B C   1 
ATOM   4973 O  O   . THR B 1 244 ? 123.242 154.534 114.097 1.00 71.27  ? 244 THR B O   1 
ATOM   4974 C  CB  . THR B 1 244 ? 121.365 155.035 111.958 1.00 67.61  ? 244 THR B CB  1 
ATOM   4975 O  OG1 . THR B 1 244 ? 122.581 155.758 112.183 1.00 70.38  ? 244 THR B OG1 1 
ATOM   4976 C  CG2 . THR B 1 244 ? 120.237 156.019 111.698 1.00 64.37  ? 244 THR B CG2 1 
ATOM   4977 N  N   . TYR B 1 245 ? 122.412 152.443 114.196 1.00 57.84  ? 245 TYR B N   1 
ATOM   4978 C  CA  . TYR B 1 245 ? 123.513 151.915 114.995 1.00 58.41  ? 245 TYR B CA  1 
ATOM   4979 C  C   . TYR B 1 245 ? 124.704 151.650 114.085 1.00 59.50  ? 245 TYR B C   1 
ATOM   4980 O  O   . TYR B 1 245 ? 124.782 150.612 113.425 1.00 61.33  ? 245 TYR B O   1 
ATOM   4981 C  CB  . TYR B 1 245 ? 123.075 150.657 115.733 1.00 57.55  ? 245 TYR B CB  1 
ATOM   4982 C  CG  . TYR B 1 245 ? 122.114 150.940 116.861 1.00 57.43  ? 245 TYR B CG  1 
ATOM   4983 C  CD1 . TYR B 1 245 ? 122.571 151.378 118.093 1.00 55.42  ? 245 TYR B CD1 1 
ATOM   4984 C  CD2 . TYR B 1 245 ? 120.748 150.792 116.687 1.00 58.43  ? 245 TYR B CD2 1 
ATOM   4985 C  CE1 . TYR B 1 245 ? 121.697 151.649 119.121 1.00 54.59  ? 245 TYR B CE1 1 
ATOM   4986 C  CE2 . TYR B 1 245 ? 119.868 151.057 117.710 1.00 57.48  ? 245 TYR B CE2 1 
ATOM   4987 C  CZ  . TYR B 1 245 ? 120.348 151.487 118.923 1.00 58.37  ? 245 TYR B CZ  1 
ATOM   4988 O  OH  . TYR B 1 245 ? 119.473 151.753 119.947 1.00 62.07  ? 245 TYR B OH  1 
ATOM   4989 N  N   . HIS B 1 246 ? 125.635 152.599 114.048 1.00 61.65  ? 246 HIS B N   1 
ATOM   4990 C  CA  . HIS B 1 246 ? 126.877 152.477 113.296 1.00 62.68  ? 246 HIS B CA  1 
ATOM   4991 C  C   . HIS B 1 246 ? 128.030 152.532 114.286 1.00 61.81  ? 246 HIS B C   1 
ATOM   4992 O  O   . HIS B 1 246 ? 128.232 153.555 114.947 1.00 64.66  ? 246 HIS B O   1 
ATOM   4993 C  CB  . HIS B 1 246 ? 126.998 153.592 112.255 1.00 65.99  ? 246 HIS B CB  1 
ATOM   4994 C  CG  . HIS B 1 246 ? 128.308 153.605 111.533 1.00 69.22  ? 246 HIS B CG  1 
ATOM   4995 N  ND1 . HIS B 1 246 ? 128.731 152.561 110.739 1.00 69.90  ? 246 HIS B ND1 1 
ATOM   4996 C  CD2 . HIS B 1 246 ? 129.290 154.536 111.484 1.00 67.56  ? 246 HIS B CD2 1 
ATOM   4997 C  CE1 . HIS B 1 246 ? 129.917 152.848 110.232 1.00 67.51  ? 246 HIS B CE1 1 
ATOM   4998 N  NE2 . HIS B 1 246 ? 130.278 154.041 110.669 1.00 68.26  ? 246 HIS B NE2 1 
ATOM   4999 N  N   . TRP B 1 247 ? 128.780 151.438 114.389 1.00 52.82  ? 247 TRP B N   1 
ATOM   5000 C  CA  . TRP B 1 247 ? 129.791 151.272 115.432 1.00 56.00  ? 247 TRP B CA  1 
ATOM   5001 C  C   . TRP B 1 247 ? 131.173 151.215 114.796 1.00 54.77  ? 247 TRP B C   1 
ATOM   5002 O  O   . TRP B 1 247 ? 131.624 150.151 114.363 1.00 56.52  ? 247 TRP B O   1 
ATOM   5003 C  CB  . TRP B 1 247 ? 129.509 150.020 116.257 1.00 54.36  ? 247 TRP B CB  1 
ATOM   5004 C  CG  . TRP B 1 247 ? 128.261 150.135 117.051 1.00 50.47  ? 247 TRP B CG  1 
ATOM   5005 C  CD1 . TRP B 1 247 ? 127.114 149.428 116.876 1.00 47.16  ? 247 TRP B CD1 1 
ATOM   5006 C  CD2 . TRP B 1 247 ? 128.020 151.032 118.137 1.00 49.41  ? 247 TRP B CD2 1 
ATOM   5007 N  NE1 . TRP B 1 247 ? 126.173 149.822 117.790 1.00 50.51  ? 247 TRP B NE1 1 
ATOM   5008 C  CE2 . TRP B 1 247 ? 126.705 150.809 118.576 1.00 49.83  ? 247 TRP B CE2 1 
ATOM   5009 C  CE3 . TRP B 1 247 ? 128.791 152.001 118.781 1.00 50.57  ? 247 TRP B CE3 1 
ATOM   5010 C  CZ2 . TRP B 1 247 ? 126.144 151.516 119.631 1.00 48.42  ? 247 TRP B CZ2 1 
ATOM   5011 C  CZ3 . TRP B 1 247 ? 128.233 152.700 119.824 1.00 52.44  ? 247 TRP B CZ3 1 
ATOM   5012 C  CH2 . TRP B 1 247 ? 126.923 152.455 120.241 1.00 49.24  ? 247 TRP B CH2 1 
ATOM   5013 N  N   . ALA B 1 248 ? 131.845 152.359 114.750 1.00 63.74  ? 248 ALA B N   1 
ATOM   5014 C  CA  . ALA B 1 248 ? 133.217 152.392 114.271 1.00 65.97  ? 248 ALA B CA  1 
ATOM   5015 C  C   . ALA B 1 248 ? 134.148 151.764 115.300 1.00 67.09  ? 248 ALA B C   1 
ATOM   5016 O  O   . ALA B 1 248 ? 133.929 151.862 116.510 1.00 67.67  ? 248 ALA B O   1 
ATOM   5017 C  CB  . ALA B 1 248 ? 133.648 153.827 113.979 1.00 65.22  ? 248 ALA B CB  1 
ATOM   5018 N  N   . SER B 1 249 ? 135.192 151.106 114.809 1.00 75.36  ? 249 SER B N   1 
ATOM   5019 C  CA  . SER B 1 249 ? 136.146 150.463 115.699 1.00 75.90  ? 249 SER B CA  1 
ATOM   5020 C  C   . SER B 1 249 ? 136.917 151.503 116.503 1.00 75.34  ? 249 SER B C   1 
ATOM   5021 O  O   . SER B 1 249 ? 137.153 152.624 116.050 1.00 73.49  ? 249 SER B O   1 
ATOM   5022 C  CB  . SER B 1 249 ? 137.117 149.592 114.908 1.00 74.86  ? 249 SER B CB  1 
ATOM   5023 O  OG  . SER B 1 249 ? 138.065 148.993 115.772 1.00 77.10  ? 249 SER B OG  1 
ATOM   5024 N  N   . PHE B 1 250 ? 137.311 151.113 117.717 1.00 71.00  ? 250 PHE B N   1 
ATOM   5025 C  CA  . PHE B 1 250 ? 138.009 152.036 118.605 1.00 70.71  ? 250 PHE B CA  1 
ATOM   5026 C  C   . PHE B 1 250 ? 139.355 152.451 118.028 1.00 71.97  ? 250 PHE B C   1 
ATOM   5027 O  O   . PHE B 1 250 ? 139.778 153.601 118.186 1.00 73.11  ? 250 PHE B O   1 
ATOM   5028 C  CB  . PHE B 1 250 ? 138.190 151.398 119.980 1.00 69.50  ? 250 PHE B CB  1 
ATOM   5029 C  CG  . PHE B 1 250 ? 138.820 152.306 120.995 1.00 68.54  ? 250 PHE B CG  1 
ATOM   5030 C  CD1 . PHE B 1 250 ? 140.192 152.357 121.142 1.00 68.52  ? 250 PHE B CD1 1 
ATOM   5031 C  CD2 . PHE B 1 250 ? 138.038 153.102 121.806 1.00 69.04  ? 250 PHE B CD2 1 
ATOM   5032 C  CE1 . PHE B 1 250 ? 140.765 153.185 122.073 1.00 70.76  ? 250 PHE B CE1 1 
ATOM   5033 C  CE2 . PHE B 1 250 ? 138.609 153.932 122.738 1.00 67.19  ? 250 PHE B CE2 1 
ATOM   5034 C  CZ  . PHE B 1 250 ? 139.973 153.973 122.872 1.00 68.63  ? 250 PHE B CZ  1 
ATOM   5035 N  N   . LYS B 1 251 ? 140.052 151.522 117.375 1.00 77.77  ? 251 LYS B N   1 
ATOM   5036 C  CA  . LYS B 1 251 ? 141.359 151.840 116.813 1.00 79.56  ? 251 LYS B CA  1 
ATOM   5037 C  C   . LYS B 1 251 ? 141.253 152.825 115.658 1.00 79.34  ? 251 LYS B C   1 
ATOM   5038 O  O   . LYS B 1 251 ? 142.144 153.663 115.477 1.00 79.94  ? 251 LYS B O   1 
ATOM   5039 C  CB  . LYS B 1 251 ? 142.055 150.559 116.356 1.00 77.64  ? 251 LYS B CB  1 
ATOM   5040 C  CG  . LYS B 1 251 ? 141.875 149.389 117.308 1.00 76.95  ? 251 LYS B CG  1 
ATOM   5041 C  CD  . LYS B 1 251 ? 142.190 148.068 116.629 1.00 77.77  ? 251 LYS B CD  1 
ATOM   5042 C  CE  . LYS B 1 251 ? 141.347 147.878 115.382 1.00 78.23  ? 251 LYS B CE  1 
ATOM   5043 N  NZ  . LYS B 1 251 ? 141.642 146.589 114.701 1.00 78.78  ? 251 LYS B NZ  1 
ATOM   5044 N  N   . ASP B 1 252 ? 140.178 152.743 114.871 1.00 77.82  ? 252 ASP B N   1 
ATOM   5045 C  CA  . ASP B 1 252 ? 140.079 153.555 113.662 1.00 78.99  ? 252 ASP B CA  1 
ATOM   5046 C  C   . ASP B 1 252 ? 139.902 155.033 113.986 1.00 79.23  ? 252 ASP B C   1 
ATOM   5047 O  O   . ASP B 1 252 ? 140.409 155.894 113.258 1.00 81.37  ? 252 ASP B O   1 
ATOM   5048 C  CB  . ASP B 1 252 ? 138.930 153.052 112.792 1.00 81.14  ? 252 ASP B CB  1 
ATOM   5049 C  CG  . ASP B 1 252 ? 139.045 151.577 112.480 1.00 81.31  ? 252 ASP B CG  1 
ATOM   5050 O  OD1 . ASP B 1 252 ? 140.054 150.963 112.885 1.00 79.27  ? 252 ASP B OD1 1 
ATOM   5051 O  OD2 . ASP B 1 252 ? 138.128 151.032 111.832 1.00 81.46  ? 252 ASP B OD2 1 
ATOM   5052 N  N   . ILE B 1 253 ? 139.181 155.350 115.063 1.00 77.96  ? 253 ILE B N   1 
ATOM   5053 C  CA  . ILE B 1 253 ? 138.964 156.747 115.419 1.00 79.34  ? 253 ILE B CA  1 
ATOM   5054 C  C   . ILE B 1 253 ? 140.290 157.388 115.795 1.00 80.83  ? 253 ILE B C   1 
ATOM   5055 O  O   . ILE B 1 253 ? 141.072 156.832 116.575 1.00 79.53  ? 253 ILE B O   1 
ATOM   5056 C  CB  . ILE B 1 253 ? 137.946 156.865 116.561 1.00 78.93  ? 253 ILE B CB  1 
ATOM   5057 C  CG1 . ILE B 1 253 ? 136.649 156.142 116.203 1.00 78.41  ? 253 ILE B CG1 1 
ATOM   5058 C  CG2 . ILE B 1 253 ? 137.664 158.321 116.867 1.00 78.55  ? 253 ILE B CG2 1 
ATOM   5059 C  CD1 . ILE B 1 253 ? 136.095 155.314 117.327 1.00 75.99  ? 253 ILE B CD1 1 
ATOM   5060 N  N   . HIS B 1 254 ? 140.548 158.570 115.239 1.00 83.33  ? 254 HIS B N   1 
ATOM   5061 C  CA  . HIS B 1 254 ? 141.803 159.280 115.452 1.00 82.19  ? 254 HIS B CA  1 
ATOM   5062 C  C   . HIS B 1 254 ? 141.693 160.360 116.520 1.00 82.97  ? 254 HIS B C   1 
ATOM   5063 O  O   . HIS B 1 254 ? 142.575 160.477 117.374 1.00 82.19  ? 254 HIS B O   1 
ATOM   5064 C  CB  . HIS B 1 254 ? 142.283 159.889 114.130 1.00 81.33  ? 254 HIS B CB  1 
ATOM   5065 C  CG  . HIS B 1 254 ? 142.391 158.896 113.015 1.00 83.94  ? 254 HIS B CG  1 
ATOM   5066 N  ND1 . HIS B 1 254 ? 143.366 157.923 112.978 1.00 81.55  ? 254 HIS B ND1 1 
ATOM   5067 C  CD2 . HIS B 1 254 ? 141.643 158.722 111.900 1.00 84.23  ? 254 HIS B CD2 1 
ATOM   5068 C  CE1 . HIS B 1 254 ? 143.215 157.193 111.887 1.00 81.38  ? 254 HIS B CE1 1 
ATOM   5069 N  NE2 . HIS B 1 254 ? 142.176 157.657 111.216 1.00 83.06  ? 254 HIS B NE2 1 
ATOM   5070 N  N   . THR B 1 255 ? 140.629 161.157 116.489 1.00 88.35  ? 255 THR B N   1 
ATOM   5071 C  CA  . THR B 1 255 ? 140.442 162.183 117.504 1.00 89.72  ? 255 THR B CA  1 
ATOM   5072 C  C   . THR B 1 255 ? 140.218 161.543 118.868 1.00 88.13  ? 255 THR B C   1 
ATOM   5073 O  O   . THR B 1 255 ? 139.512 160.539 118.994 1.00 87.33  ? 255 THR B O   1 
ATOM   5074 C  CB  . THR B 1 255 ? 139.259 163.083 117.148 1.00 86.94  ? 255 THR B CB  1 
ATOM   5075 O  OG1 . THR B 1 255 ? 138.049 162.316 117.160 1.00 85.96  ? 255 THR B OG1 1 
ATOM   5076 C  CG2 . THR B 1 255 ? 139.451 163.691 115.771 1.00 84.46  ? 255 THR B CG2 1 
ATOM   5077 N  N   . THR B 1 256 ? 140.832 162.131 119.896 1.00 83.26  ? 256 THR B N   1 
ATOM   5078 C  CA  . THR B 1 256 ? 140.696 161.592 121.244 1.00 84.90  ? 256 THR B CA  1 
ATOM   5079 C  C   . THR B 1 256 ? 139.265 161.688 121.750 1.00 82.44  ? 256 THR B C   1 
ATOM   5080 O  O   . THR B 1 256 ? 138.803 160.792 122.464 1.00 77.93  ? 256 THR B O   1 
ATOM   5081 C  CB  . THR B 1 256 ? 141.641 162.318 122.197 1.00 85.78  ? 256 THR B CB  1 
ATOM   5082 O  OG1 . THR B 1 256 ? 141.381 163.726 122.144 1.00 83.96  ? 256 THR B OG1 1 
ATOM   5083 C  CG2 . THR B 1 256 ? 143.083 162.059 121.803 1.00 83.90  ? 256 THR B CG2 1 
ATOM   5084 N  N   . THR B 1 257 ? 138.553 162.763 121.405 1.00 81.88  ? 257 THR B N   1 
ATOM   5085 C  CA  . THR B 1 257 ? 137.162 162.888 121.823 1.00 82.15  ? 257 THR B CA  1 
ATOM   5086 C  C   . THR B 1 257 ? 136.295 161.798 121.208 1.00 83.41  ? 257 THR B C   1 
ATOM   5087 O  O   . THR B 1 257 ? 135.322 161.357 121.828 1.00 82.04  ? 257 THR B O   1 
ATOM   5088 C  CB  . THR B 1 257 ? 136.621 164.274 121.464 1.00 82.27  ? 257 THR B CB  1 
ATOM   5089 O  OG1 . THR B 1 257 ? 135.227 164.346 121.786 1.00 84.18  ? 257 THR B OG1 1 
ATOM   5090 C  CG2 . THR B 1 257 ? 136.810 164.565 119.982 1.00 79.66  ? 257 THR B CG2 1 
ATOM   5091 N  N   . GLY B 1 258 ? 136.623 161.359 119.992 1.00 76.85  ? 258 GLY B N   1 
ATOM   5092 C  CA  . GLY B 1 258 ? 135.937 160.212 119.423 1.00 73.97  ? 258 GLY B CA  1 
ATOM   5093 C  C   . GLY B 1 258 ? 136.266 158.923 120.150 1.00 74.70  ? 258 GLY B C   1 
ATOM   5094 O  O   . GLY B 1 258 ? 135.393 158.076 120.355 1.00 73.86  ? 258 GLY B O   1 
ATOM   5095 N  N   . LYS B 1 259 ? 137.530 158.753 120.543 1.00 73.84  ? 259 LYS B N   1 
ATOM   5096 C  CA  . LYS B 1 259 ? 137.914 157.576 121.315 1.00 72.06  ? 259 LYS B CA  1 
ATOM   5097 C  C   . LYS B 1 259 ? 137.207 157.547 122.663 1.00 72.24  ? 259 LYS B C   1 
ATOM   5098 O  O   . LYS B 1 259 ? 136.746 156.491 123.109 1.00 72.37  ? 259 LYS B O   1 
ATOM   5099 C  CB  . LYS B 1 259 ? 139.429 157.548 121.506 1.00 71.42  ? 259 LYS B CB  1 
ATOM   5100 C  CG  . LYS B 1 259 ? 140.201 157.069 120.295 1.00 72.13  ? 259 LYS B CG  1 
ATOM   5101 C  CD  . LYS B 1 259 ? 141.649 156.785 120.649 1.00 72.49  ? 259 LYS B CD  1 
ATOM   5102 C  CE  . LYS B 1 259 ? 142.293 155.845 119.645 1.00 72.81  ? 259 LYS B CE  1 
ATOM   5103 N  NZ  . LYS B 1 259 ? 142.491 156.495 118.325 1.00 72.60  ? 259 LYS B NZ  1 
ATOM   5104 N  N   . ILE B 1 260 ? 137.122 158.697 123.333 1.00 68.41  ? 260 ILE B N   1 
ATOM   5105 C  CA  . ILE B 1 260 ? 136.389 158.771 124.595 1.00 66.10  ? 260 ILE B CA  1 
ATOM   5106 C  C   . ILE B 1 260 ? 134.913 158.490 124.360 1.00 67.74  ? 260 ILE B C   1 
ATOM   5107 O  O   . ILE B 1 260 ? 134.261 157.802 125.154 1.00 70.65  ? 260 ILE B O   1 
ATOM   5108 C  CB  . ILE B 1 260 ? 136.605 160.141 125.267 1.00 66.02  ? 260 ILE B CB  1 
ATOM   5109 C  CG1 . ILE B 1 260 ? 138.086 160.399 125.567 1.00 69.69  ? 260 ILE B CG1 1 
ATOM   5110 C  CG2 . ILE B 1 260 ? 135.792 160.243 126.540 1.00 65.64  ? 260 ILE B CG2 1 
ATOM   5111 C  CD1 . ILE B 1 260 ? 138.932 159.158 125.789 1.00 70.22  ? 260 ILE B CD1 1 
ATOM   5112 N  N   . LYS B 1 261 ? 134.362 159.025 123.270 1.00 66.27  ? 261 LYS B N   1 
ATOM   5113 C  CA  . LYS B 1 261 ? 132.974 158.741 122.928 1.00 61.45  ? 261 LYS B CA  1 
ATOM   5114 C  C   . LYS B 1 261 ? 132.769 157.258 122.653 1.00 61.92  ? 261 LYS B C   1 
ATOM   5115 O  O   . LYS B 1 261 ? 131.791 156.666 123.117 1.00 64.35  ? 261 LYS B O   1 
ATOM   5116 C  CB  . LYS B 1 261 ? 132.553 159.579 121.720 1.00 62.50  ? 261 LYS B CB  1 
ATOM   5117 C  CG  . LYS B 1 261 ? 131.101 159.406 121.316 1.00 64.66  ? 261 LYS B CG  1 
ATOM   5118 C  CD  . LYS B 1 261 ? 130.729 160.340 120.174 1.00 68.17  ? 261 LYS B CD  1 
ATOM   5119 C  CE  . LYS B 1 261 ? 129.307 160.090 119.685 1.00 64.67  ? 261 LYS B CE  1 
ATOM   5120 N  NZ  . LYS B 1 261 ? 128.284 160.363 120.732 1.00 64.95  ? 261 LYS B NZ  1 
ATOM   5121 N  N   . ARG B 1 262 ? 133.688 156.637 121.910 1.00 56.90  ? 262 ARG B N   1 
ATOM   5122 C  CA  . ARG B 1 262 ? 133.540 155.222 121.589 1.00 54.10  ? 262 ARG B CA  1 
ATOM   5123 C  C   . ARG B 1 262 ? 133.725 154.346 122.820 1.00 55.32  ? 262 ARG B C   1 
ATOM   5124 O  O   . ARG B 1 262 ? 133.022 153.344 122.983 1.00 59.36  ? 262 ARG B O   1 
ATOM   5125 C  CB  . ARG B 1 262 ? 134.531 154.821 120.502 1.00 55.89  ? 262 ARG B CB  1 
ATOM   5126 C  CG  . ARG B 1 262 ? 134.432 153.367 120.090 1.00 53.43  ? 262 ARG B CG  1 
ATOM   5127 C  CD  . ARG B 1 262 ? 133.009 152.993 119.735 1.00 56.20  ? 262 ARG B CD  1 
ATOM   5128 N  NE  . ARG B 1 262 ? 132.890 151.583 119.388 1.00 59.71  ? 262 ARG B NE  1 
ATOM   5129 C  CZ  . ARG B 1 262 ? 132.840 150.596 120.270 1.00 55.40  ? 262 ARG B CZ  1 
ATOM   5130 N  NH1 . ARG B 1 262 ? 132.903 150.827 121.569 1.00 54.61  ? 262 ARG B NH1 1 
ATOM   5131 N  NH2 . ARG B 1 262 ? 132.722 149.346 119.837 1.00 51.79  ? 262 ARG B NH2 1 
ATOM   5132 N  N   . ALA B 1 263 ? 134.673 154.695 123.688 1.00 54.91  ? 263 ALA B N   1 
ATOM   5133 C  CA  . ALA B 1 263 ? 134.879 153.917 124.905 1.00 54.81  ? 263 ALA B CA  1 
ATOM   5134 C  C   . ALA B 1 263 ? 133.648 153.966 125.799 1.00 55.16  ? 263 ALA B C   1 
ATOM   5135 O  O   . ALA B 1 263 ? 133.208 152.940 126.328 1.00 59.61  ? 263 ALA B O   1 
ATOM   5136 C  CB  . ALA B 1 263 ? 136.107 154.430 125.652 1.00 57.17  ? 263 ALA B CB  1 
ATOM   5137 N  N   . VAL B 1 264 ? 133.076 155.158 125.977 1.00 48.84  ? 264 VAL B N   1 
ATOM   5138 C  CA  . VAL B 1 264 ? 131.894 155.303 126.819 1.00 46.37  ? 264 VAL B CA  1 
ATOM   5139 C  C   . VAL B 1 264 ? 130.686 154.643 126.168 1.00 47.01  ? 264 VAL B C   1 
ATOM   5140 O  O   . VAL B 1 264 ? 129.856 154.030 126.849 1.00 47.92  ? 264 VAL B O   1 
ATOM   5141 C  CB  . VAL B 1 264 ? 131.642 156.791 127.119 1.00 47.68  ? 264 VAL B CB  1 
ATOM   5142 C  CG1 . VAL B 1 264 ? 130.296 156.986 127.779 1.00 51.37  ? 264 VAL B CG1 1 
ATOM   5143 C  CG2 . VAL B 1 264 ? 132.741 157.336 128.004 1.00 49.22  ? 264 VAL B CG2 1 
ATOM   5144 N  N   . LEU B 1 265 ? 130.576 154.737 124.842 1.00 50.65  ? 265 LEU B N   1 
ATOM   5145 C  CA  . LEU B 1 265 ? 129.429 154.182 124.134 1.00 49.85  ? 265 LEU B CA  1 
ATOM   5146 C  C   . LEU B 1 265 ? 129.397 152.662 124.155 1.00 48.02  ? 265 LEU B C   1 
ATOM   5147 O  O   . LEU B 1 265 ? 128.393 152.079 123.735 1.00 48.65  ? 265 LEU B O   1 
ATOM   5148 C  CB  . LEU B 1 265 ? 129.410 154.668 122.686 1.00 47.39  ? 265 LEU B CB  1 
ATOM   5149 C  CG  . LEU B 1 265 ? 128.734 156.008 122.399 1.00 44.52  ? 265 LEU B CG  1 
ATOM   5150 C  CD1 . LEU B 1 265 ? 128.518 156.169 120.910 1.00 47.58  ? 265 LEU B CD1 1 
ATOM   5151 C  CD2 . LEU B 1 265 ? 127.425 156.126 123.145 1.00 47.11  ? 265 LEU B CD2 1 
ATOM   5152 N  N   . GLN B 1 266 ? 130.465 152.007 124.610 1.00 45.23  ? 266 GLN B N   1 
ATOM   5153 C  CA  . GLN B 1 266 ? 130.443 150.557 124.749 1.00 45.45  ? 266 GLN B CA  1 
ATOM   5154 C  C   . GLN B 1 266 ? 129.463 150.093 125.818 1.00 46.33  ? 266 GLN B C   1 
ATOM   5155 O  O   . GLN B 1 266 ? 128.968 148.965 125.743 1.00 47.40  ? 266 GLN B O   1 
ATOM   5156 C  CB  . GLN B 1 266 ? 131.847 150.042 125.063 1.00 41.44  ? 266 GLN B CB  1 
ATOM   5157 C  CG  . GLN B 1 266 ? 131.940 148.542 125.219 1.00 43.33  ? 266 GLN B CG  1 
ATOM   5158 C  CD  . GLN B 1 266 ? 131.875 147.819 123.899 1.00 45.28  ? 266 GLN B CD  1 
ATOM   5159 O  OE1 . GLN B 1 266 ? 131.875 148.440 122.842 1.00 48.78  ? 266 GLN B OE1 1 
ATOM   5160 N  NE2 . GLN B 1 266 ? 131.825 146.497 123.951 1.00 43.26  ? 266 GLN B NE2 1 
ATOM   5161 N  N   . PHE B 1 267 ? 129.154 150.938 126.798 1.00 45.03  ? 267 PHE B N   1 
ATOM   5162 C  CA  . PHE B 1 267 ? 128.236 150.583 127.869 1.00 42.85  ? 267 PHE B CA  1 
ATOM   5163 C  C   . PHE B 1 267 ? 126.789 150.922 127.536 1.00 44.54  ? 267 PHE B C   1 
ATOM   5164 O  O   . PHE B 1 267 ? 125.972 151.073 128.450 1.00 44.31  ? 267 PHE B O   1 
ATOM   5165 C  CB  . PHE B 1 267 ? 128.664 151.264 129.168 1.00 40.15  ? 267 PHE B CB  1 
ATOM   5166 C  CG  . PHE B 1 267 ? 129.971 150.762 129.694 1.00 41.02  ? 267 PHE B CG  1 
ATOM   5167 C  CD1 . PHE B 1 267 ? 131.161 151.311 129.261 1.00 44.73  ? 267 PHE B CD1 1 
ATOM   5168 C  CD2 . PHE B 1 267 ? 130.012 149.719 130.594 1.00 44.84  ? 267 PHE B CD2 1 
ATOM   5169 C  CE1 . PHE B 1 267 ? 132.363 150.840 129.728 1.00 45.78  ? 267 PHE B CE1 1 
ATOM   5170 C  CE2 . PHE B 1 267 ? 131.212 149.245 131.062 1.00 47.04  ? 267 PHE B CE2 1 
ATOM   5171 C  CZ  . PHE B 1 267 ? 132.388 149.808 130.631 1.00 45.20  ? 267 PHE B CZ  1 
ATOM   5172 N  N   . THR B 1 268 ? 126.461 151.041 126.257 1.00 39.13  ? 268 THR B N   1 
ATOM   5173 C  CA  . THR B 1 268 ? 125.121 151.301 125.762 1.00 42.72  ? 268 THR B CA  1 
ATOM   5174 C  C   . THR B 1 268 ? 124.740 150.216 124.764 1.00 44.02  ? 268 THR B C   1 
ATOM   5175 O  O   . THR B 1 268 ? 125.617 149.584 124.167 1.00 48.71  ? 268 THR B O   1 
ATOM   5176 C  CB  . THR B 1 268 ? 125.035 152.682 125.095 1.00 41.41  ? 268 THR B CB  1 
ATOM   5177 O  OG1 . THR B 1 268 ? 125.712 152.651 123.835 1.00 43.77  ? 268 THR B OG1 1 
ATOM   5178 C  CG2 . THR B 1 268 ? 125.664 153.741 125.977 1.00 35.57  ? 268 THR B CG2 1 
ATOM   5179 N  N   . PRO B 1 269 ? 123.445 149.955 124.571 1.00 38.32  ? 269 PRO B N   1 
ATOM   5180 C  CA  . PRO B 1 269 ? 123.044 148.859 123.681 1.00 36.91  ? 269 PRO B CA  1 
ATOM   5181 C  C   . PRO B 1 269 ? 123.549 149.059 122.261 1.00 43.09  ? 269 PRO B C   1 
ATOM   5182 O  O   . PRO B 1 269 ? 123.545 150.170 121.730 1.00 47.02  ? 269 PRO B O   1 
ATOM   5183 C  CB  . PRO B 1 269 ? 121.513 148.898 123.738 1.00 38.28  ? 269 PRO B CB  1 
ATOM   5184 C  CG  . PRO B 1 269 ? 121.174 150.227 124.296 1.00 38.74  ? 269 PRO B CG  1 
ATOM   5185 C  CD  . PRO B 1 269 ? 122.281 150.576 125.220 1.00 40.20  ? 269 PRO B CD  1 
ATOM   5186 N  N   . ALA B 1 270 ? 123.984 147.959 121.647 1.00 43.94  ? 270 ALA B N   1 
ATOM   5187 C  CA  . ALA B 1 270 ? 124.435 147.978 120.263 1.00 38.58  ? 270 ALA B CA  1 
ATOM   5188 C  C   . ALA B 1 270 ? 123.290 147.880 119.268 1.00 47.19  ? 270 ALA B C   1 
ATOM   5189 O  O   . ALA B 1 270 ? 123.499 148.141 118.080 1.00 52.02  ? 270 ALA B O   1 
ATOM   5190 C  CB  . ALA B 1 270 ? 125.423 146.839 120.018 1.00 36.94  ? 270 ALA B CB  1 
ATOM   5191 N  N   . SER B 1 271 ? 122.097 147.510 119.721 1.00 46.52  ? 271 SER B N   1 
ATOM   5192 C  CA  . SER B 1 271 ? 120.917 147.448 118.872 1.00 42.73  ? 271 SER B CA  1 
ATOM   5193 C  C   . SER B 1 271 ? 119.694 147.410 119.772 1.00 43.04  ? 271 SER B C   1 
ATOM   5194 O  O   . SER B 1 271 ? 119.793 147.122 120.965 1.00 38.94  ? 271 SER B O   1 
ATOM   5195 C  CB  . SER B 1 271 ? 120.953 146.233 117.945 1.00 43.87  ? 271 SER B CB  1 
ATOM   5196 O  OG  . SER B 1 271 ? 121.335 145.070 118.654 1.00 49.54  ? 271 SER B OG  1 
ATOM   5197 N  N   . TRP B 1 272 ? 118.537 147.707 119.190 1.00 51.08  ? 272 TRP B N   1 
ATOM   5198 C  CA  . TRP B 1 272 ? 117.291 147.752 119.942 1.00 51.56  ? 272 TRP B CA  1 
ATOM   5199 C  C   . TRP B 1 272 ? 116.216 146.981 119.198 1.00 53.78  ? 272 TRP B C   1 
ATOM   5200 O  O   . TRP B 1 272 ? 115.975 147.232 118.013 1.00 55.47  ? 272 TRP B O   1 
ATOM   5201 C  CB  . TRP B 1 272 ? 116.842 149.191 120.188 1.00 48.70  ? 272 TRP B CB  1 
ATOM   5202 C  CG  . TRP B 1 272 ? 116.141 149.359 121.488 1.00 48.92  ? 272 TRP B CG  1 
ATOM   5203 C  CD1 . TRP B 1 272 ? 114.867 149.791 121.679 1.00 53.44  ? 272 TRP B CD1 1 
ATOM   5204 C  CD2 . TRP B 1 272 ? 116.673 149.089 122.788 1.00 48.37  ? 272 TRP B CD2 1 
ATOM   5205 N  NE1 . TRP B 1 272 ? 114.571 149.810 123.018 1.00 54.31  ? 272 TRP B NE1 1 
ATOM   5206 C  CE2 . TRP B 1 272 ? 115.667 149.385 123.719 1.00 49.45  ? 272 TRP B CE2 1 
ATOM   5207 C  CE3 . TRP B 1 272 ? 117.906 148.630 123.254 1.00 46.19  ? 272 TRP B CE3 1 
ATOM   5208 C  CZ2 . TRP B 1 272 ? 115.852 149.235 125.086 1.00 49.59  ? 272 TRP B CZ2 1 
ATOM   5209 C  CZ3 . TRP B 1 272 ? 118.087 148.482 124.609 1.00 49.34  ? 272 TRP B CZ3 1 
ATOM   5210 C  CH2 . TRP B 1 272 ? 117.067 148.782 125.510 1.00 50.81  ? 272 TRP B CH2 1 
ATOM   5211 N  N   . THR B 1 273 ? 115.575 146.050 119.896 1.00 56.08  ? 273 THR B N   1 
ATOM   5212 C  CA  . THR B 1 273 ? 114.500 145.269 119.310 1.00 53.75  ? 273 THR B CA  1 
ATOM   5213 C  C   . THR B 1 273 ? 113.204 146.066 119.311 1.00 53.14  ? 273 THR B C   1 
ATOM   5214 O  O   . THR B 1 273 ? 112.905 146.796 120.259 1.00 56.56  ? 273 THR B O   1 
ATOM   5215 C  CB  . THR B 1 273 ? 114.316 143.970 120.090 1.00 53.37  ? 273 THR B CB  1 
ATOM   5216 O  OG1 . THR B 1 273 ? 115.590 143.344 120.270 1.00 50.75  ? 273 THR B OG1 1 
ATOM   5217 C  CG2 . THR B 1 273 ? 113.399 143.019 119.343 1.00 52.99  ? 273 THR B CG2 1 
ATOM   5218 N  N   . TYR B 1 274 ? 112.431 145.927 118.240 1.00 57.89  ? 274 TYR B N   1 
ATOM   5219 C  CA  . TYR B 1 274 ? 111.119 146.555 118.142 1.00 59.38  ? 274 TYR B CA  1 
ATOM   5220 C  C   . TYR B 1 274 ? 110.108 145.642 118.825 1.00 62.34  ? 274 TYR B C   1 
ATOM   5221 O  O   . TYR B 1 274 ? 109.865 144.522 118.367 1.00 68.17  ? 274 TYR B O   1 
ATOM   5222 C  CB  . TYR B 1 274 ? 110.756 146.808 116.683 1.00 61.22  ? 274 TYR B CB  1 
ATOM   5223 C  CG  . TYR B 1 274 ? 109.476 147.583 116.491 1.00 63.49  ? 274 TYR B CG  1 
ATOM   5224 C  CD1 . TYR B 1 274 ? 109.225 148.737 117.217 1.00 63.85  ? 274 TYR B CD1 1 
ATOM   5225 C  CD2 . TYR B 1 274 ? 108.524 147.167 115.574 1.00 63.39  ? 274 TYR B CD2 1 
ATOM   5226 C  CE1 . TYR B 1 274 ? 108.056 149.449 117.043 1.00 63.63  ? 274 TYR B CE1 1 
ATOM   5227 C  CE2 . TYR B 1 274 ? 107.356 147.875 115.390 1.00 64.32  ? 274 TYR B CE2 1 
ATOM   5228 C  CZ  . TYR B 1 274 ? 107.125 149.014 116.128 1.00 65.24  ? 274 TYR B CZ  1 
ATOM   5229 O  OH  . TYR B 1 274 ? 105.959 149.721 115.948 1.00 65.25  ? 274 TYR B OH  1 
ATOM   5230 N  N   . VAL B 1 275 ? 109.520 146.120 119.919 1.00 47.64  ? 275 VAL B N   1 
ATOM   5231 C  CA  . VAL B 1 275 ? 108.664 145.311 120.778 1.00 45.53  ? 275 VAL B CA  1 
ATOM   5232 C  C   . VAL B 1 275 ? 107.207 145.590 120.441 1.00 53.01  ? 275 VAL B C   1 
ATOM   5233 O  O   . VAL B 1 275 ? 106.770 146.747 120.441 1.00 56.29  ? 275 VAL B O   1 
ATOM   5234 C  CB  . VAL B 1 275 ? 108.947 145.595 122.262 1.00 41.46  ? 275 VAL B CB  1 
ATOM   5235 C  CG1 . VAL B 1 275 ? 108.271 144.571 123.133 1.00 44.16  ? 275 VAL B CG1 1 
ATOM   5236 C  CG2 . VAL B 1 275 ? 110.430 145.590 122.516 1.00 45.98  ? 275 VAL B CG2 1 
ATOM   5237 N  N   . ARG B 1 276 ? 106.456 144.529 120.154 1.00 55.45  ? 276 ARG B N   1 
ATOM   5238 C  CA  . ARG B 1 276 ? 105.016 144.611 119.911 1.00 52.12  ? 276 ARG B CA  1 
ATOM   5239 C  C   . ARG B 1 276 ? 104.373 143.464 120.679 1.00 54.82  ? 276 ARG B C   1 
ATOM   5240 O  O   . ARG B 1 276 ? 104.341 142.331 120.193 1.00 58.47  ? 276 ARG B O   1 
ATOM   5241 C  CB  . ARG B 1 276 ? 104.685 144.525 118.427 1.00 56.35  ? 276 ARG B CB  1 
ATOM   5242 C  CG  . ARG B 1 276 ? 105.180 145.683 117.591 1.00 53.01  ? 276 ARG B CG  1 
ATOM   5243 C  CD  . ARG B 1 276 ? 105.257 145.286 116.127 1.00 57.74  ? 276 ARG B CD  1 
ATOM   5244 N  NE  . ARG B 1 276 ? 106.471 144.535 115.833 1.00 63.21  ? 276 ARG B NE  1 
ATOM   5245 C  CZ  . ARG B 1 276 ? 106.597 143.674 114.832 1.00 65.22  ? 276 ARG B CZ  1 
ATOM   5246 N  NH1 . ARG B 1 276 ? 105.598 143.431 114.000 1.00 60.68  ? 276 ARG B NH1 1 
ATOM   5247 N  NH2 . ARG B 1 276 ? 107.754 143.042 114.661 1.00 61.20  ? 276 ARG B NH2 1 
ATOM   5248 N  N   . TRP B 1 277 ? 103.869 143.755 121.877 1.00 46.00  ? 277 TRP B N   1 
ATOM   5249 C  CA  . TRP B 1 277 ? 103.279 142.700 122.691 1.00 45.89  ? 277 TRP B CA  1 
ATOM   5250 C  C   . TRP B 1 277 ? 101.973 142.196 122.099 1.00 45.41  ? 277 TRP B C   1 
ATOM   5251 O  O   . TRP B 1 277 ? 101.674 141.001 122.192 1.00 47.81  ? 277 TRP B O   1 
ATOM   5252 C  CB  . TRP B 1 277 ? 103.066 143.199 124.119 1.00 40.56  ? 277 TRP B CB  1 
ATOM   5253 C  CG  . TRP B 1 277 ? 104.346 143.445 124.842 1.00 39.99  ? 277 TRP B CG  1 
ATOM   5254 C  CD1 . TRP B 1 277 ? 104.996 144.631 124.970 1.00 36.25  ? 277 TRP B CD1 1 
ATOM   5255 C  CD2 . TRP B 1 277 ? 105.142 142.475 125.528 1.00 39.83  ? 277 TRP B CD2 1 
ATOM   5256 N  NE1 . TRP B 1 277 ? 106.146 144.464 125.694 1.00 38.90  ? 277 TRP B NE1 1 
ATOM   5257 C  CE2 . TRP B 1 277 ? 106.259 143.146 126.048 1.00 37.90  ? 277 TRP B CE2 1 
ATOM   5258 C  CE3 . TRP B 1 277 ? 105.019 141.102 125.750 1.00 39.74  ? 277 TRP B CE3 1 
ATOM   5259 C  CZ2 . TRP B 1 277 ? 107.244 142.495 126.779 1.00 39.00  ? 277 TRP B CZ2 1 
ATOM   5260 C  CZ3 . TRP B 1 277 ? 105.995 140.460 126.475 1.00 37.36  ? 277 TRP B CZ3 1 
ATOM   5261 C  CH2 . TRP B 1 277 ? 107.094 141.155 126.981 1.00 35.57  ? 277 TRP B CH2 1 
ATOM   5262 N  N   . PHE B 1 278 ? 101.193 143.076 121.480 1.00 65.07  ? 278 PHE B N   1 
ATOM   5263 C  CA  . PHE B 1 278 ? 99.874  142.734 120.974 1.00 66.13  ? 278 PHE B CA  1 
ATOM   5264 C  C   . PHE B 1 278 ? 99.823  142.891 119.463 1.00 66.09  ? 278 PHE B C   1 
ATOM   5265 O  O   . PHE B 1 278 ? 100.479 143.762 118.887 1.00 64.39  ? 278 PHE B O   1 
ATOM   5266 C  CB  . PHE B 1 278 ? 98.790  143.613 121.601 1.00 66.91  ? 278 PHE B CB  1 
ATOM   5267 C  CG  . PHE B 1 278 ? 98.708  143.503 123.089 1.00 63.80  ? 278 PHE B CG  1 
ATOM   5268 C  CD1 . PHE B 1 278 ? 99.160  144.531 123.893 1.00 63.33  ? 278 PHE B CD1 1 
ATOM   5269 C  CD2 . PHE B 1 278 ? 98.187  142.370 123.685 1.00 63.89  ? 278 PHE B CD2 1 
ATOM   5270 C  CE1 . PHE B 1 278 ? 99.089  144.435 125.258 1.00 65.89  ? 278 PHE B CE1 1 
ATOM   5271 C  CE2 . PHE B 1 278 ? 98.115  142.267 125.052 1.00 65.83  ? 278 PHE B CE2 1 
ATOM   5272 C  CZ  . PHE B 1 278 ? 98.567  143.300 125.840 1.00 71.06  ? 278 PHE B CZ  1 
ATOM   5273 N  N   . ASP B 1 279 ? 99.023  142.043 118.832 1.00 81.00  ? 279 ASP B N   1 
ATOM   5274 C  CA  . ASP B 1 279 ? 98.710  142.133 117.417 1.00 84.82  ? 279 ASP B CA  1 
ATOM   5275 C  C   . ASP B 1 279 ? 97.201  142.082 117.240 1.00 86.90  ? 279 ASP B C   1 
ATOM   5276 O  O   . ASP B 1 279 ? 96.497  141.502 118.072 1.00 82.48  ? 279 ASP B O   1 
ATOM   5277 C  CB  . ASP B 1 279 ? 99.361  140.989 116.626 1.00 82.85  ? 279 ASP B CB  1 
ATOM   5278 C  CG  . ASP B 1 279 ? 100.866 141.109 116.562 1.00 81.69  ? 279 ASP B CG  1 
ATOM   5279 O  OD1 . ASP B 1 279 ? 101.363 142.157 116.104 1.00 84.40  ? 279 ASP B OD1 1 
ATOM   5280 O  OD2 . ASP B 1 279 ? 101.553 140.150 116.963 1.00 79.99  ? 279 ASP B OD2 1 
ATOM   5281 N  N   . PRO B 1 280 ? 96.674  142.699 116.181 1.00 97.43  ? 280 PRO B N   1 
ATOM   5282 C  CA  . PRO B 1 280 ? 95.227  142.596 115.935 1.00 97.57  ? 280 PRO B CA  1 
ATOM   5283 C  C   . PRO B 1 280 ? 94.766  141.168 115.718 1.00 97.11  ? 280 PRO B C   1 
ATOM   5284 O  O   . PRO B 1 280 ? 93.629  140.828 116.069 1.00 95.45  ? 280 PRO B O   1 
ATOM   5285 C  CB  . PRO B 1 280 ? 95.021  143.458 114.682 1.00 94.64  ? 280 PRO B CB  1 
ATOM   5286 C  CG  . PRO B 1 280 ? 96.211  144.362 114.637 1.00 95.98  ? 280 PRO B CG  1 
ATOM   5287 C  CD  . PRO B 1 280 ? 97.342  143.555 115.188 1.00 94.18  ? 280 PRO B CD  1 
ATOM   5288 N  N   . LYS B 1 281 ? 95.621  140.318 115.151 1.00 94.05  ? 281 LYS B N   1 
ATOM   5289 C  CA  . LYS B 1 281 ? 95.313  138.915 114.921 1.00 92.79  ? 281 LYS B CA  1 
ATOM   5290 C  C   . LYS B 1 281 ? 95.909  138.010 115.992 1.00 94.26  ? 281 LYS B C   1 
ATOM   5291 O  O   . LYS B 1 281 ? 95.994  136.795 115.786 1.00 96.56  ? 281 LYS B O   1 
ATOM   5292 C  CB  . LYS B 1 281 ? 95.809  138.486 113.540 1.00 94.65  ? 281 LYS B CB  1 
ATOM   5293 C  CG  . LYS B 1 281 ? 95.322  139.357 112.392 1.00 95.94  ? 281 LYS B CG  1 
ATOM   5294 C  CD  . LYS B 1 281 ? 93.809  139.321 112.265 1.00 94.97  ? 281 LYS B CD  1 
ATOM   5295 C  CE  . LYS B 1 281 ? 93.344  140.097 111.046 1.00 94.73  ? 281 LYS B CE  1 
ATOM   5296 N  NZ  . LYS B 1 281 ? 93.864  141.491 111.046 1.00 96.30  ? 281 LYS B NZ  1 
ATOM   5297 N  N   . SER B 1 282 ? 96.333  138.579 117.119 1.00 86.79  ? 282 SER B N   1 
ATOM   5298 C  CA  . SER B 1 282 ? 96.991  137.799 118.160 1.00 85.01  ? 282 SER B CA  1 
ATOM   5299 C  C   . SER B 1 282 ? 96.061  136.721 118.699 1.00 81.94  ? 282 SER B C   1 
ATOM   5300 O  O   . SER B 1 282 ? 94.891  136.978 118.992 1.00 78.12  ? 282 SER B O   1 
ATOM   5301 C  CB  . SER B 1 282 ? 97.453  138.717 119.289 1.00 83.20  ? 282 SER B CB  1 
ATOM   5302 O  OG  . SER B 1 282 ? 96.456  139.672 119.602 1.00 83.18  ? 282 SER B OG  1 
ATOM   5303 N  N   . SER B 1 283 ? 96.594  135.512 118.838 1.00 75.04  ? 283 SER B N   1 
ATOM   5304 C  CA  . SER B 1 283 ? 95.791  134.360 119.207 1.00 76.37  ? 283 SER B CA  1 
ATOM   5305 C  C   . SER B 1 283 ? 95.427  134.410 120.688 1.00 75.85  ? 283 SER B C   1 
ATOM   5306 O  O   . SER B 1 283 ? 95.719  135.372 121.404 1.00 74.01  ? 283 SER B O   1 
ATOM   5307 C  CB  . SER B 1 283 ? 96.539  133.072 118.876 1.00 73.68  ? 283 SER B CB  1 
ATOM   5308 O  OG  . SER B 1 283 ? 97.910  133.183 119.215 1.00 72.42  ? 283 SER B OG  1 
ATOM   5309 N  N   . PHE B 1 284 ? 94.758  133.352 121.147 1.00 69.13  ? 284 PHE B N   1 
ATOM   5310 C  CA  . PHE B 1 284 ? 94.468  133.213 122.567 1.00 64.07  ? 284 PHE B CA  1 
ATOM   5311 C  C   . PHE B 1 284 ? 95.708  132.821 123.353 1.00 65.01  ? 284 PHE B C   1 
ATOM   5312 O  O   . PHE B 1 284 ? 95.755  133.038 124.567 1.00 69.42  ? 284 PHE B O   1 
ATOM   5313 C  CB  . PHE B 1 284 ? 93.369  132.171 122.787 1.00 66.77  ? 284 PHE B CB  1 
ATOM   5314 C  CG  . PHE B 1 284 ? 91.990  132.630 122.381 1.00 73.10  ? 284 PHE B CG  1 
ATOM   5315 C  CD1 . PHE B 1 284 ? 91.811  133.761 121.602 1.00 71.84  ? 284 PHE B CD1 1 
ATOM   5316 C  CD2 . PHE B 1 284 ? 90.871  131.914 122.775 1.00 72.34  ? 284 PHE B CD2 1 
ATOM   5317 C  CE1 . PHE B 1 284 ? 90.547  134.172 121.230 1.00 68.27  ? 284 PHE B CE1 1 
ATOM   5318 C  CE2 . PHE B 1 284 ? 89.604  132.321 122.406 1.00 71.34  ? 284 PHE B CE2 1 
ATOM   5319 C  CZ  . PHE B 1 284 ? 89.442  133.452 121.633 1.00 69.86  ? 284 PHE B CZ  1 
ATOM   5320 N  N   . GLN B 1 285 ? 96.700  132.229 122.688 1.00 57.49  ? 285 GLN B N   1 
ATOM   5321 C  CA  . GLN B 1 285 ? 97.950  131.887 123.355 1.00 53.15  ? 285 GLN B CA  1 
ATOM   5322 C  C   . GLN B 1 285 ? 98.777  133.134 123.634 1.00 57.98  ? 285 GLN B C   1 
ATOM   5323 O  O   . GLN B 1 285 ? 99.312  133.303 124.733 1.00 63.32  ? 285 GLN B O   1 
ATOM   5324 C  CB  . GLN B 1 285 ? 98.740  130.902 122.497 1.00 56.58  ? 285 GLN B CB  1 
ATOM   5325 C  CG  . GLN B 1 285 ? 98.287  129.463 122.619 1.00 60.06  ? 285 GLN B CG  1 
ATOM   5326 C  CD  . GLN B 1 285 ? 99.117  128.677 123.610 1.00 66.01  ? 285 GLN B CD  1 
ATOM   5327 O  OE1 . GLN B 1 285 ? 99.170  129.010 124.792 1.00 65.22  ? 285 GLN B OE1 1 
ATOM   5328 N  NE2 . GLN B 1 285 ? 99.780  127.633 123.130 1.00 61.75  ? 285 GLN B NE2 1 
ATOM   5329 N  N   . ARG B 1 286 ? 98.895  134.021 122.645 1.00 58.04  ? 286 ARG B N   1 
ATOM   5330 C  CA  . ARG B 1 286 ? 99.678  135.237 122.834 1.00 51.82  ? 286 ARG B CA  1 
ATOM   5331 C  C   . ARG B 1 286 ? 99.022  136.165 123.842 1.00 49.00  ? 286 ARG B C   1 
ATOM   5332 O  O   . ARG B 1 286 ? 99.709  136.799 124.647 1.00 55.96  ? 286 ARG B O   1 
ATOM   5333 C  CB  . ARG B 1 286 ? 99.869  135.951 121.501 1.00 51.90  ? 286 ARG B CB  1 
ATOM   5334 C  CG  . ARG B 1 286 ? 100.727 137.190 121.583 1.00 48.57  ? 286 ARG B CG  1 
ATOM   5335 C  CD  . ARG B 1 286 ? 101.762 137.191 120.481 1.00 54.63  ? 286 ARG B CD  1 
ATOM   5336 N  NE  . ARG B 1 286 ? 102.335 138.512 120.267 1.00 53.11  ? 286 ARG B NE  1 
ATOM   5337 C  CZ  . ARG B 1 286 ? 103.069 138.840 119.215 1.00 56.49  ? 286 ARG B CZ  1 
ATOM   5338 N  NH1 . ARG B 1 286 ? 103.346 137.963 118.266 1.00 56.50  ? 286 ARG B NH1 1 
ATOM   5339 N  NH2 . ARG B 1 286 ? 103.528 140.082 119.107 1.00 56.03  ? 286 ARG B NH2 1 
ATOM   5340 N  N   . VAL B 1 287 ? 97.694  136.260 123.808 1.00 51.77  ? 287 VAL B N   1 
ATOM   5341 C  CA  . VAL B 1 287 ? 96.982  137.141 124.728 1.00 48.21  ? 287 VAL B CA  1 
ATOM   5342 C  C   . VAL B 1 287 ? 97.168  136.668 126.162 1.00 44.41  ? 287 VAL B C   1 
ATOM   5343 O  O   . VAL B 1 287 ? 97.299  137.476 127.088 1.00 52.10  ? 287 VAL B O   1 
ATOM   5344 C  CB  . VAL B 1 287 ? 95.496  137.213 124.337 1.00 54.62  ? 287 VAL B CB  1 
ATOM   5345 C  CG1 . VAL B 1 287 ? 94.621  137.506 125.545 1.00 51.97  ? 287 VAL B CG1 1 
ATOM   5346 C  CG2 . VAL B 1 287 ? 95.295  138.240 123.243 1.00 53.34  ? 287 VAL B CG2 1 
ATOM   5347 N  N   . ALA B 1 288 ? 97.197  135.356 126.366 1.00 39.15  ? 288 ALA B N   1 
ATOM   5348 C  CA  . ALA B 1 288 ? 97.419  134.772 127.680 1.00 35.08  ? 288 ALA B CA  1 
ATOM   5349 C  C   . ALA B 1 288 ? 98.895  134.615 128.016 1.00 38.75  ? 288 ALA B C   1 
ATOM   5350 O  O   . ALA B 1 288 ? 99.218  134.103 129.089 1.00 45.98  ? 288 ALA B O   1 
ATOM   5351 C  CB  . ALA B 1 288 ? 96.722  133.415 127.779 1.00 36.05  ? 288 ALA B CB  1 
ATOM   5352 N  N   . GLY B 1 289 ? 99.794  135.021 127.128 1.00 35.93  ? 289 GLY B N   1 
ATOM   5353 C  CA  . GLY B 1 289 ? 101.204 135.040 127.452 1.00 34.28  ? 289 GLY B CA  1 
ATOM   5354 C  C   . GLY B 1 289 ? 101.623 136.388 127.991 1.00 40.93  ? 289 GLY B C   1 
ATOM   5355 O  O   . GLY B 1 289 ? 102.618 136.500 128.710 1.00 44.43  ? 289 GLY B O   1 
ATOM   5356 N  N   . VAL B 1 290 ? 100.869 137.427 127.628 1.00 43.73  ? 290 VAL B N   1 
ATOM   5357 C  CA  . VAL B 1 290 ? 101.029 138.731 128.256 1.00 33.52  ? 290 VAL B CA  1 
ATOM   5358 C  C   . VAL B 1 290 ? 100.225 138.821 129.543 1.00 40.58  ? 290 VAL B C   1 
ATOM   5359 O  O   . VAL B 1 290 ? 100.486 139.697 130.372 1.00 50.29  ? 290 VAL B O   1 
ATOM   5360 C  CB  . VAL B 1 290 ? 100.613 139.854 127.294 1.00 34.49  ? 290 VAL B CB  1 
ATOM   5361 C  CG1 . VAL B 1 290 ? 101.251 141.162 127.700 1.00 41.80  ? 290 VAL B CG1 1 
ATOM   5362 C  CG2 . VAL B 1 290 ? 100.997 139.498 125.881 1.00 39.42  ? 290 VAL B CG2 1 
ATOM   5363 N  N   . TYR B 1 291 ? 99.243  137.942 129.728 1.00 39.96  ? 291 TYR B N   1 
ATOM   5364 C  CA  . TYR B 1 291 ? 98.532  137.880 130.997 1.00 41.91  ? 291 TYR B CA  1 
ATOM   5365 C  C   . TYR B 1 291 ? 99.370  137.200 132.069 1.00 44.54  ? 291 TYR B C   1 
ATOM   5366 O  O   . TYR B 1 291 ? 99.329  137.598 133.236 1.00 48.60  ? 291 TYR B O   1 
ATOM   5367 C  CB  . TYR B 1 291 ? 97.206  137.150 130.820 1.00 39.19  ? 291 TYR B CB  1 
ATOM   5368 C  CG  . TYR B 1 291 ? 96.356  137.150 132.059 1.00 41.81  ? 291 TYR B CG  1 
ATOM   5369 C  CD1 . TYR B 1 291 ? 95.852  138.331 132.570 1.00 47.22  ? 291 TYR B CD1 1 
ATOM   5370 C  CD2 . TYR B 1 291 ? 96.060  135.973 132.721 1.00 43.34  ? 291 TYR B CD2 1 
ATOM   5371 C  CE1 . TYR B 1 291 ? 95.076  138.340 133.699 1.00 46.52  ? 291 TYR B CE1 1 
ATOM   5372 C  CE2 . TYR B 1 291 ? 95.282  135.973 133.854 1.00 45.56  ? 291 TYR B CE2 1 
ATOM   5373 C  CZ  . TYR B 1 291 ? 94.795  137.163 134.339 1.00 47.99  ? 291 TYR B CZ  1 
ATOM   5374 O  OH  . TYR B 1 291 ? 94.014  137.182 135.465 1.00 49.19  ? 291 TYR B OH  1 
ATOM   5375 N  N   . LEU B 1 292 ? 100.123 136.166 131.698 1.00 38.05  ? 292 LEU B N   1 
ATOM   5376 C  CA  . LEU B 1 292 ? 101.059 135.563 132.637 1.00 31.80  ? 292 LEU B CA  1 
ATOM   5377 C  C   . LEU B 1 292 ? 102.261 136.464 132.871 1.00 38.16  ? 292 LEU B C   1 
ATOM   5378 O  O   . LEU B 1 292 ? 102.876 136.411 133.939 1.00 50.85  ? 292 LEU B O   1 
ATOM   5379 C  CB  . LEU B 1 292 ? 101.506 134.198 132.120 1.00 38.42  ? 292 LEU B CB  1 
ATOM   5380 C  CG  . LEU B 1 292 ? 102.636 133.490 132.861 1.00 40.65  ? 292 LEU B CG  1 
ATOM   5381 C  CD1 . LEU B 1 292 ? 102.171 133.049 134.232 1.00 43.06  ? 292 LEU B CD1 1 
ATOM   5382 C  CD2 . LEU B 1 292 ? 103.134 132.306 132.057 1.00 41.23  ? 292 LEU B CD2 1 
ATOM   5383 N  N   . PHE B 1 293 ? 102.611 137.295 131.891 1.00 32.58  ? 293 PHE B N   1 
ATOM   5384 C  CA  . PHE B 1 293 ? 103.727 138.214 132.071 1.00 24.41  ? 293 PHE B CA  1 
ATOM   5385 C  C   . PHE B 1 293 ? 103.431 139.231 133.159 1.00 29.59  ? 293 PHE B C   1 
ATOM   5386 O  O   . PHE B 1 293 ? 104.305 139.560 133.965 1.00 44.77  ? 293 PHE B O   1 
ATOM   5387 C  CB  . PHE B 1 293 ? 104.040 138.922 130.756 1.00 31.63  ? 293 PHE B CB  1 
ATOM   5388 C  CG  . PHE B 1 293 ? 105.210 139.850 130.834 1.00 35.17  ? 293 PHE B CG  1 
ATOM   5389 C  CD1 . PHE B 1 293 ? 106.497 139.358 130.819 1.00 36.78  ? 293 PHE B CD1 1 
ATOM   5390 C  CD2 . PHE B 1 293 ? 105.022 141.213 130.917 1.00 32.48  ? 293 PHE B CD2 1 
ATOM   5391 C  CE1 . PHE B 1 293 ? 107.571 140.203 130.886 1.00 32.98  ? 293 PHE B CE1 1 
ATOM   5392 C  CE2 . PHE B 1 293 ? 106.094 142.061 130.989 1.00 30.96  ? 293 PHE B CE2 1 
ATOM   5393 C  CZ  . PHE B 1 293 ? 107.369 141.553 130.973 1.00 31.26  ? 293 PHE B CZ  1 
ATOM   5394 N  N   . MET B 1 294 ? 102.207 139.740 133.200 1.00 32.19  ? 294 MET B N   1 
ATOM   5395 C  CA  . MET B 1 294 ? 101.825 140.759 134.163 1.00 31.94  ? 294 MET B CA  1 
ATOM   5396 C  C   . MET B 1 294 ? 101.342 140.183 135.485 1.00 37.87  ? 294 MET B C   1 
ATOM   5397 O  O   . MET B 1 294 ? 100.975 140.948 136.379 1.00 40.27  ? 294 MET B O   1 
ATOM   5398 C  CB  . MET B 1 294 ? 100.751 141.661 133.565 1.00 35.44  ? 294 MET B CB  1 
ATOM   5399 C  CG  . MET B 1 294 ? 101.267 142.545 132.454 1.00 39.86  ? 294 MET B CG  1 
ATOM   5400 S  SD  . MET B 1 294 ? 99.953  143.512 131.714 1.00 62.54  ? 294 MET B SD  1 
ATOM   5401 C  CE  . MET B 1 294 ? 98.599  142.370 131.902 1.00 43.68  ? 294 MET B CE  1 
ATOM   5402 N  N   . ILE B 1 295 ? 101.326 138.863 135.629 1.00 42.11  ? 295 ILE B N   1 
ATOM   5403 C  CA  . ILE B 1 295 ? 101.104 138.247 136.931 1.00 40.75  ? 295 ILE B CA  1 
ATOM   5404 C  C   . ILE B 1 295 ? 102.425 137.920 137.610 1.00 38.76  ? 295 ILE B C   1 
ATOM   5405 O  O   . ILE B 1 295 ? 102.586 138.152 138.808 1.00 48.64  ? 295 ILE B O   1 
ATOM   5406 C  CB  . ILE B 1 295 ? 100.225 136.996 136.780 1.00 34.07  ? 295 ILE B CB  1 
ATOM   5407 C  CG1 . ILE B 1 295 ? 98.768  137.396 136.606 1.00 36.01  ? 295 ILE B CG1 1 
ATOM   5408 C  CG2 . ILE B 1 295 ? 100.371 136.093 137.980 1.00 36.41  ? 295 ILE B CG2 1 
ATOM   5409 C  CD1 . ILE B 1 295 ? 97.921  136.268 136.132 1.00 44.21  ? 295 ILE B CD1 1 
ATOM   5410 N  N   . ILE B 1 296 ? 103.389 137.385 136.861 1.00 28.42  ? 296 ILE B N   1 
ATOM   5411 C  CA  . ILE B 1 296 ? 104.720 137.198 137.422 1.00 30.36  ? 296 ILE B CA  1 
ATOM   5412 C  C   . ILE B 1 296 ? 105.376 138.544 137.693 1.00 34.39  ? 296 ILE B C   1 
ATOM   5413 O  O   . ILE B 1 296 ? 106.200 138.664 138.604 1.00 45.41  ? 296 ILE B O   1 
ATOM   5414 C  CB  . ILE B 1 296 ? 105.587 136.325 136.499 1.00 35.87  ? 296 ILE B CB  1 
ATOM   5415 C  CG1 . ILE B 1 296 ? 104.809 135.100 136.032 1.00 33.66  ? 296 ILE B CG1 1 
ATOM   5416 C  CG2 . ILE B 1 296 ? 106.840 135.877 137.225 1.00 39.92  ? 296 ILE B CG2 1 
ATOM   5417 C  CD1 . ILE B 1 296 ? 104.210 134.299 137.150 1.00 42.53  ? 296 ILE B CD1 1 
ATOM   5418 N  N   . TRP B 1 297 ? 105.038 139.573 136.914 1.00 33.93  ? 297 TRP B N   1 
ATOM   5419 C  CA  . TRP B 1 297 ? 105.532 140.913 137.212 1.00 37.17  ? 297 TRP B CA  1 
ATOM   5420 C  C   . TRP B 1 297 ? 105.001 141.393 138.555 1.00 39.49  ? 297 TRP B C   1 
ATOM   5421 O  O   . TRP B 1 297 ? 105.758 141.899 139.388 1.00 53.05  ? 297 TRP B O   1 
ATOM   5422 C  CB  . TRP B 1 297 ? 105.139 141.879 136.091 1.00 37.43  ? 297 TRP B CB  1 
ATOM   5423 C  CG  . TRP B 1 297 ? 105.656 143.297 136.222 1.00 35.87  ? 297 TRP B CG  1 
ATOM   5424 C  CD1 . TRP B 1 297 ? 106.210 143.879 137.324 1.00 35.72  ? 297 TRP B CD1 1 
ATOM   5425 C  CD2 . TRP B 1 297 ? 105.647 144.307 135.205 1.00 44.08  ? 297 TRP B CD2 1 
ATOM   5426 N  NE1 . TRP B 1 297 ? 106.549 145.179 137.057 1.00 41.12  ? 297 TRP B NE1 1 
ATOM   5427 C  CE2 . TRP B 1 297 ? 106.213 145.467 135.762 1.00 44.47  ? 297 TRP B CE2 1 
ATOM   5428 C  CE3 . TRP B 1 297 ? 105.218 144.340 133.875 1.00 40.67  ? 297 TRP B CE3 1 
ATOM   5429 C  CZ2 . TRP B 1 297 ? 106.359 146.644 135.039 1.00 44.08  ? 297 TRP B CZ2 1 
ATOM   5430 C  CZ3 . TRP B 1 297 ? 105.359 145.510 133.164 1.00 41.75  ? 297 TRP B CZ3 1 
ATOM   5431 C  CH2 . TRP B 1 297 ? 105.925 146.645 133.745 1.00 43.06  ? 297 TRP B CH2 1 
ATOM   5432 N  N   . GLN B 1 298 ? 103.701 141.231 138.792 1.00 39.95  ? 298 GLN B N   1 
ATOM   5433 C  CA  . GLN B 1 298 ? 103.124 141.665 140.055 1.00 39.37  ? 298 GLN B CA  1 
ATOM   5434 C  C   . GLN B 1 298 ? 103.389 140.692 141.190 1.00 42.91  ? 298 GLN B C   1 
ATOM   5435 O  O   . GLN B 1 298 ? 103.275 141.079 142.355 1.00 50.45  ? 298 GLN B O   1 
ATOM   5436 C  CB  . GLN B 1 298 ? 101.623 141.869 139.909 1.00 39.60  ? 298 GLN B CB  1 
ATOM   5437 C  CG  . GLN B 1 298 ? 101.251 142.901 138.884 1.00 49.37  ? 298 GLN B CG  1 
ATOM   5438 C  CD  . GLN B 1 298 ? 100.010 143.665 139.260 1.00 50.37  ? 298 GLN B CD  1 
ATOM   5439 O  OE1 . GLN B 1 298 ? 98.962  143.504 138.638 1.00 51.32  ? 298 GLN B OE1 1 
ATOM   5440 N  NE2 . GLN B 1 298 ? 100.115 144.502 140.284 1.00 44.13  ? 298 GLN B NE2 1 
ATOM   5441 N  N   . LEU B 1 299 ? 103.723 139.441 140.882 1.00 40.63  ? 299 LEU B N   1 
ATOM   5442 C  CA  . LEU B 1 299 ? 104.172 138.530 141.925 1.00 31.97  ? 299 LEU B CA  1 
ATOM   5443 C  C   . LEU B 1 299 ? 105.492 138.997 142.514 1.00 34.79  ? 299 LEU B C   1 
ATOM   5444 O  O   . LEU B 1 299 ? 105.712 138.883 143.723 1.00 46.19  ? 299 LEU B O   1 
ATOM   5445 C  CB  . LEU B 1 299 ? 104.303 137.117 141.370 1.00 33.37  ? 299 LEU B CB  1 
ATOM   5446 C  CG  . LEU B 1 299 ? 104.501 135.992 142.379 1.00 35.72  ? 299 LEU B CG  1 
ATOM   5447 C  CD1 . LEU B 1 299 ? 103.230 135.757 143.162 1.00 40.22  ? 299 LEU B CD1 1 
ATOM   5448 C  CD2 . LEU B 1 299 ? 104.924 134.731 141.658 1.00 38.39  ? 299 LEU B CD2 1 
ATOM   5449 N  N   . THR B 1 300 ? 106.379 139.534 141.677 1.00 30.30  ? 300 THR B N   1 
ATOM   5450 C  CA  . THR B 1 300 ? 107.664 140.028 142.152 1.00 33.30  ? 300 THR B CA  1 
ATOM   5451 C  C   . THR B 1 300 ? 107.539 141.297 142.979 1.00 35.64  ? 300 THR B C   1 
ATOM   5452 O  O   . THR B 1 300 ? 108.531 141.726 143.573 1.00 36.84  ? 300 THR B O   1 
ATOM   5453 C  CB  . THR B 1 300 ? 108.603 140.277 140.976 1.00 34.76  ? 300 THR B CB  1 
ATOM   5454 O  OG1 . THR B 1 300 ? 108.008 141.220 140.081 1.00 38.23  ? 300 THR B OG1 1 
ATOM   5455 C  CG2 . THR B 1 300 ? 108.875 138.986 140.239 1.00 28.07  ? 300 THR B CG2 1 
ATOM   5456 N  N   . GLU B 1 301 ? 106.360 141.910 143.022 1.00 45.16  ? 301 GLU B N   1 
ATOM   5457 C  CA  . GLU B 1 301 ? 106.123 143.051 143.893 1.00 45.19  ? 301 GLU B CA  1 
ATOM   5458 C  C   . GLU B 1 301 ? 105.529 142.645 145.232 1.00 42.13  ? 301 GLU B C   1 
ATOM   5459 O  O   . GLU B 1 301 ? 105.714 143.358 146.223 1.00 49.86  ? 301 GLU B O   1 
ATOM   5460 C  CB  . GLU B 1 301 ? 105.203 144.057 143.203 1.00 47.08  ? 301 GLU B CB  1 
ATOM   5461 C  CG  . GLU B 1 301 ? 105.855 144.799 142.057 1.00 47.55  ? 301 GLU B CG  1 
ATOM   5462 C  CD  . GLU B 1 301 ? 106.574 146.051 142.509 1.00 55.97  ? 301 GLU B CD  1 
ATOM   5463 O  OE1 . GLU B 1 301 ? 107.036 146.086 143.668 1.00 53.48  ? 301 GLU B OE1 1 
ATOM   5464 O  OE2 . GLU B 1 301 ? 106.679 147.001 141.707 1.00 55.51  ? 301 GLU B OE2 1 
ATOM   5465 N  N   . LEU B 1 302 ? 104.812 141.523 145.285 1.00 38.75  ? 302 LEU B N   1 
ATOM   5466 C  CA  . LEU B 1 302 ? 104.405 140.974 146.572 1.00 43.26  ? 302 LEU B CA  1 
ATOM   5467 C  C   . LEU B 1 302 ? 105.577 140.319 147.287 1.00 43.41  ? 302 LEU B C   1 
ATOM   5468 O  O   . LEU B 1 302 ? 105.602 140.274 148.520 1.00 49.38  ? 302 LEU B O   1 
ATOM   5469 C  CB  . LEU B 1 302 ? 103.277 139.964 146.388 1.00 37.76  ? 302 LEU B CB  1 
ATOM   5470 C  CG  . LEU B 1 302 ? 102.029 140.474 145.683 1.00 39.75  ? 302 LEU B CG  1 
ATOM   5471 C  CD1 . LEU B 1 302 ? 101.235 139.315 145.135 1.00 47.76  ? 302 LEU B CD1 1 
ATOM   5472 C  CD2 . LEU B 1 302 ? 101.199 141.284 146.645 1.00 45.07  ? 302 LEU B CD2 1 
ATOM   5473 N  N   . ASN B 1 303 ? 106.544 139.794 146.534 1.00 38.58  ? 303 ASN B N   1 
ATOM   5474 C  CA  . ASN B 1 303 ? 107.751 139.260 147.149 1.00 33.20  ? 303 ASN B CA  1 
ATOM   5475 C  C   . ASN B 1 303 ? 108.527 140.352 147.869 1.00 46.42  ? 303 ASN B C   1 
ATOM   5476 O  O   . ASN B 1 303 ? 108.998 140.148 148.991 1.00 59.00  ? 303 ASN B O   1 
ATOM   5477 C  CB  . ASN B 1 303 ? 108.628 138.596 146.092 1.00 31.72  ? 303 ASN B CB  1 
ATOM   5478 C  CG  . ASN B 1 303 ? 107.920 137.480 145.374 1.00 39.36  ? 303 ASN B CG  1 
ATOM   5479 O  OD1 . ASN B 1 303 ? 106.813 137.099 145.741 1.00 43.08  ? 303 ASN B OD1 1 
ATOM   5480 N  ND2 . ASN B 1 303 ? 108.552 136.948 144.340 1.00 40.88  ? 303 ASN B ND2 1 
ATOM   5481 N  N   . THR B 1 304 ? 108.671 141.518 147.244 1.00 42.42  ? 304 THR B N   1 
ATOM   5482 C  CA  . THR B 1 304 ? 109.406 142.601 147.886 1.00 40.44  ? 304 THR B CA  1 
ATOM   5483 C  C   . THR B 1 304 ? 108.668 143.115 149.115 1.00 43.19  ? 304 THR B C   1 
ATOM   5484 O  O   . THR B 1 304 ? 109.291 143.419 150.136 1.00 50.81  ? 304 THR B O   1 
ATOM   5485 C  CB  . THR B 1 304 ? 109.657 143.732 146.890 1.00 43.50  ? 304 THR B CB  1 
ATOM   5486 O  OG1 . THR B 1 304 ? 110.549 143.281 145.865 1.00 46.09  ? 304 THR B OG1 1 
ATOM   5487 C  CG2 . THR B 1 304 ? 110.281 144.921 147.582 1.00 44.95  ? 304 THR B CG2 1 
ATOM   5488 N  N   . PHE B 1 305 ? 107.339 143.211 149.040 1.00 43.32  ? 305 PHE B N   1 
ATOM   5489 C  CA  . PHE B 1 305 ? 106.574 143.751 150.159 1.00 39.32  ? 305 PHE B CA  1 
ATOM   5490 C  C   . PHE B 1 305 ? 106.634 142.840 151.375 1.00 47.76  ? 305 PHE B C   1 
ATOM   5491 O  O   . PHE B 1 305 ? 106.756 143.320 152.506 1.00 53.64  ? 305 PHE B O   1 
ATOM   5492 C  CB  . PHE B 1 305 ? 105.122 143.976 149.751 1.00 40.02  ? 305 PHE B CB  1 
ATOM   5493 C  CG  . PHE B 1 305 ? 104.294 144.637 150.812 1.00 47.02  ? 305 PHE B CG  1 
ATOM   5494 C  CD1 . PHE B 1 305 ? 104.358 146.004 151.005 1.00 52.37  ? 305 PHE B CD1 1 
ATOM   5495 C  CD2 . PHE B 1 305 ? 103.455 143.893 151.619 1.00 46.59  ? 305 PHE B CD2 1 
ATOM   5496 C  CE1 . PHE B 1 305 ? 103.599 146.614 151.979 1.00 48.48  ? 305 PHE B CE1 1 
ATOM   5497 C  CE2 . PHE B 1 305 ? 102.696 144.499 152.596 1.00 44.98  ? 305 PHE B CE2 1 
ATOM   5498 C  CZ  . PHE B 1 305 ? 102.769 145.861 152.775 1.00 48.62  ? 305 PHE B CZ  1 
ATOM   5499 N  N   . PHE B 1 306 ? 106.539 141.530 151.171 1.00 49.09  ? 306 PHE B N   1 
ATOM   5500 C  CA  . PHE B 1 306 ? 106.425 140.612 152.296 1.00 48.18  ? 306 PHE B CA  1 
ATOM   5501 C  C   . PHE B 1 306 ? 107.770 140.174 152.849 1.00 51.39  ? 306 PHE B C   1 
ATOM   5502 O  O   . PHE B 1 306 ? 107.886 139.959 154.060 1.00 60.15  ? 306 PHE B O   1 
ATOM   5503 C  CB  . PHE B 1 306 ? 105.607 139.385 151.894 1.00 44.55  ? 306 PHE B CB  1 
ATOM   5504 C  CG  . PHE B 1 306 ? 104.141 139.656 151.794 1.00 44.80  ? 306 PHE B CG  1 
ATOM   5505 C  CD1 . PHE B 1 306 ? 103.439 140.117 152.889 1.00 49.02  ? 306 PHE B CD1 1 
ATOM   5506 C  CD2 . PHE B 1 306 ? 103.469 139.466 150.607 1.00 45.06  ? 306 PHE B CD2 1 
ATOM   5507 C  CE1 . PHE B 1 306 ? 102.094 140.377 152.801 1.00 54.39  ? 306 PHE B CE1 1 
ATOM   5508 C  CE2 . PHE B 1 306 ? 102.124 139.726 150.514 1.00 49.70  ? 306 PHE B CE2 1 
ATOM   5509 C  CZ  . PHE B 1 306 ? 101.435 140.181 151.612 1.00 51.94  ? 306 PHE B CZ  1 
ATOM   5510 N  N   . LEU B 1 307 ? 108.788 140.033 152.001 1.00 43.79  ? 307 LEU B N   1 
ATOM   5511 C  CA  . LEU B 1 307 ? 110.114 139.707 152.509 1.00 44.41  ? 307 LEU B CA  1 
ATOM   5512 C  C   . LEU B 1 307 ? 110.618 140.798 153.441 1.00 50.84  ? 307 LEU B C   1 
ATOM   5513 O  O   . LEU B 1 307 ? 111.293 140.515 154.436 1.00 54.62  ? 307 LEU B O   1 
ATOM   5514 C  CB  . LEU B 1 307 ? 111.082 139.502 151.348 1.00 41.65  ? 307 LEU B CB  1 
ATOM   5515 C  CG  . LEU B 1 307 ? 110.931 138.205 150.559 1.00 45.22  ? 307 LEU B CG  1 
ATOM   5516 C  CD1 . LEU B 1 307 ? 111.929 138.185 149.430 1.00 46.24  ? 307 LEU B CD1 1 
ATOM   5517 C  CD2 . LEU B 1 307 ? 111.122 137.005 151.458 1.00 47.79  ? 307 LEU B CD2 1 
ATOM   5518 N  N   . LYS B 1 308 ? 110.291 142.054 153.136 1.00 55.05  ? 308 LYS B N   1 
ATOM   5519 C  CA  . LYS B 1 308 ? 110.674 143.162 154.001 1.00 53.46  ? 308 LYS B CA  1 
ATOM   5520 C  C   . LYS B 1 308 ? 109.823 143.206 155.265 1.00 54.67  ? 308 LYS B C   1 
ATOM   5521 O  O   . LYS B 1 308 ? 110.280 143.702 156.301 1.00 56.47  ? 308 LYS B O   1 
ATOM   5522 C  CB  . LYS B 1 308 ? 110.568 144.475 153.223 1.00 54.06  ? 308 LYS B CB  1 
ATOM   5523 C  CG  . LYS B 1 308 ? 110.651 145.736 154.059 1.00 58.05  ? 308 LYS B CG  1 
ATOM   5524 C  CD  . LYS B 1 308 ? 110.446 146.972 153.203 1.00 58.66  ? 308 LYS B CD  1 
ATOM   5525 C  CE  . LYS B 1 308 ? 110.827 148.236 153.957 1.00 61.46  ? 308 LYS B CE  1 
ATOM   5526 N  NZ  . LYS B 1 308 ? 109.637 149.053 154.322 1.00 57.40  ? 308 LYS B NZ  1 
ATOM   5527 N  N   . HIS B 1 309 ? 108.599 142.684 155.210 1.00 54.37  ? 309 HIS B N   1 
ATOM   5528 C  CA  . HIS B 1 309 ? 107.710 142.727 156.366 1.00 56.36  ? 309 HIS B CA  1 
ATOM   5529 C  C   . HIS B 1 309 ? 107.808 141.477 157.230 1.00 56.95  ? 309 HIS B C   1 
ATOM   5530 O  O   . HIS B 1 309 ? 107.758 141.575 158.460 1.00 62.87  ? 309 HIS B O   1 
ATOM   5531 C  CB  . HIS B 1 309 ? 106.266 142.934 155.911 1.00 56.13  ? 309 HIS B CB  1 
ATOM   5532 C  CG  . HIS B 1 309 ? 105.793 144.346 156.049 1.00 64.45  ? 309 HIS B CG  1 
ATOM   5533 N  ND1 . HIS B 1 309 ? 105.573 144.940 157.273 1.00 63.10  ? 309 HIS B ND1 1 
ATOM   5534 C  CD2 . HIS B 1 309 ? 105.515 145.290 155.118 1.00 64.55  ? 309 HIS B CD2 1 
ATOM   5535 C  CE1 . HIS B 1 309 ? 105.172 146.185 157.090 1.00 61.74  ? 309 HIS B CE1 1 
ATOM   5536 N  NE2 . HIS B 1 309 ? 105.129 146.422 155.792 1.00 61.88  ? 309 HIS B NE2 1 
ATOM   5537 N  N   . ILE B 1 310 ? 107.935 140.302 156.614 1.00 47.46  ? 310 ILE B N   1 
ATOM   5538 C  CA  . ILE B 1 310 ? 108.086 139.070 157.383 1.00 50.89  ? 310 ILE B CA  1 
ATOM   5539 C  C   . ILE B 1 310 ? 109.417 139.066 158.123 1.00 54.42  ? 310 ILE B C   1 
ATOM   5540 O  O   . ILE B 1 310 ? 109.480 138.780 159.324 1.00 51.59  ? 310 ILE B O   1 
ATOM   5541 C  CB  . ILE B 1 310 ? 107.949 137.849 156.458 1.00 48.50  ? 310 ILE B CB  1 
ATOM   5542 C  CG1 . ILE B 1 310 ? 106.487 137.643 156.081 1.00 52.12  ? 310 ILE B CG1 1 
ATOM   5543 C  CG2 . ILE B 1 310 ? 108.509 136.611 157.117 1.00 49.53  ? 310 ILE B CG2 1 
ATOM   5544 C  CD1 . ILE B 1 310 ? 106.298 136.792 154.873 1.00 51.42  ? 310 ILE B CD1 1 
ATOM   5545 N  N   . PHE B 1 311 ? 110.496 139.384 157.419 1.00 58.21  ? 311 PHE B N   1 
ATOM   5546 C  CA  . PHE B 1 311 ? 111.820 139.547 158.011 1.00 54.50  ? 311 PHE B CA  1 
ATOM   5547 C  C   . PHE B 1 311 ? 112.038 141.041 158.194 1.00 56.05  ? 311 PHE B C   1 
ATOM   5548 O  O   . PHE B 1 311 ? 112.392 141.746 157.249 1.00 58.20  ? 311 PHE B O   1 
ATOM   5549 C  CB  . PHE B 1 311 ? 112.891 138.929 157.122 1.00 50.34  ? 311 PHE B CB  1 
ATOM   5550 C  CG  . PHE B 1 311 ? 112.548 137.560 156.628 1.00 52.87  ? 311 PHE B CG  1 
ATOM   5551 C  CD1 . PHE B 1 311 ? 112.613 136.471 157.473 1.00 55.29  ? 311 PHE B CD1 1 
ATOM   5552 C  CD2 . PHE B 1 311 ? 112.151 137.363 155.320 1.00 55.42  ? 311 PHE B CD2 1 
ATOM   5553 C  CE1 . PHE B 1 311 ? 112.293 135.214 157.022 1.00 56.27  ? 311 PHE B CE1 1 
ATOM   5554 C  CE2 . PHE B 1 311 ? 111.830 136.106 154.864 1.00 56.81  ? 311 PHE B CE2 1 
ATOM   5555 C  CZ  . PHE B 1 311 ? 111.901 135.032 155.715 1.00 56.61  ? 311 PHE B CZ  1 
ATOM   5556 N  N   . VAL B 1 312 ? 111.830 141.525 159.413 1.00 58.97  ? 312 VAL B N   1 
ATOM   5557 C  CA  . VAL B 1 312 ? 111.782 142.960 159.651 1.00 60.58  ? 312 VAL B CA  1 
ATOM   5558 C  C   . VAL B 1 312 ? 113.169 143.565 159.499 1.00 62.19  ? 312 VAL B C   1 
ATOM   5559 O  O   . VAL B 1 312 ? 114.019 143.428 160.385 1.00 62.50  ? 312 VAL B O   1 
ATOM   5560 C  CB  . VAL B 1 312 ? 111.200 143.268 161.042 1.00 58.17  ? 312 VAL B CB  1 
ATOM   5561 C  CG1 . VAL B 1 312 ? 110.884 144.748 161.170 1.00 56.78  ? 312 VAL B CG1 1 
ATOM   5562 C  CG2 . VAL B 1 312 ? 109.960 142.428 161.292 1.00 57.26  ? 312 VAL B CG2 1 
ATOM   5563 N  N   . PHE B 1 313 ? 113.406 144.238 158.375 1.00 57.62  ? 313 PHE B N   1 
ATOM   5564 C  CA  . PHE B 1 313 ? 114.578 145.084 158.216 1.00 57.51  ? 313 PHE B CA  1 
ATOM   5565 C  C   . PHE B 1 313 ? 114.167 146.363 157.503 1.00 60.72  ? 313 PHE B C   1 
ATOM   5566 O  O   . PHE B 1 313 ? 113.218 146.376 156.716 1.00 57.30  ? 313 PHE B O   1 
ATOM   5567 C  CB  . PHE B 1 313 ? 115.721 144.386 157.456 1.00 57.84  ? 313 PHE B CB  1 
ATOM   5568 C  CG  . PHE B 1 313 ? 115.293 143.663 156.213 1.00 57.63  ? 313 PHE B CG  1 
ATOM   5569 C  CD1 . PHE B 1 313 ? 114.995 144.356 155.057 1.00 61.17  ? 313 PHE B CD1 1 
ATOM   5570 C  CD2 . PHE B 1 313 ? 115.226 142.284 156.193 1.00 57.25  ? 313 PHE B CD2 1 
ATOM   5571 C  CE1 . PHE B 1 313 ? 114.613 143.689 153.915 1.00 60.45  ? 313 PHE B CE1 1 
ATOM   5572 C  CE2 . PHE B 1 313 ? 114.845 141.612 155.054 1.00 55.56  ? 313 PHE B CE2 1 
ATOM   5573 C  CZ  . PHE B 1 313 ? 114.538 142.314 153.914 1.00 57.14  ? 313 PHE B CZ  1 
ATOM   5574 N  N   . GLN B 1 314 ? 114.888 147.440 157.796 1.00 72.26  ? 314 GLN B N   1 
ATOM   5575 C  CA  . GLN B 1 314 ? 114.568 148.734 157.220 1.00 70.10  ? 314 GLN B CA  1 
ATOM   5576 C  C   . GLN B 1 314 ? 114.870 148.746 155.725 1.00 71.02  ? 314 GLN B C   1 
ATOM   5577 O  O   . GLN B 1 314 ? 115.609 147.908 155.205 1.00 71.27  ? 314 GLN B O   1 
ATOM   5578 C  CB  . GLN B 1 314 ? 115.352 149.842 157.921 1.00 69.21  ? 314 GLN B CB  1 
ATOM   5579 C  CG  . GLN B 1 314 ? 115.022 149.998 159.393 1.00 73.41  ? 314 GLN B CG  1 
ATOM   5580 C  CD  . GLN B 1 314 ? 116.050 150.829 160.132 1.00 76.10  ? 314 GLN B CD  1 
ATOM   5581 O  OE1 . GLN B 1 314 ? 117.008 151.322 159.539 1.00 77.07  ? 314 GLN B OE1 1 
ATOM   5582 N  NE2 . GLN B 1 314 ? 115.859 150.984 161.437 1.00 72.44  ? 314 GLN B NE2 1 
ATOM   5583 N  N   . ALA B 1 315 ? 114.275 149.716 155.030 1.00 69.78  ? 315 ALA B N   1 
ATOM   5584 C  CA  . ALA B 1 315 ? 114.501 149.848 153.598 1.00 70.18  ? 315 ALA B CA  1 
ATOM   5585 C  C   . ALA B 1 315 ? 115.933 150.245 153.272 1.00 70.41  ? 315 ALA B C   1 
ATOM   5586 O  O   . ALA B 1 315 ? 116.365 150.068 152.130 1.00 68.76  ? 315 ALA B O   1 
ATOM   5587 C  CB  . ALA B 1 315 ? 113.530 150.866 153.004 1.00 69.99  ? 315 ALA B CB  1 
ATOM   5588 N  N   . SER B 1 316 ? 116.674 150.774 154.244 1.00 69.37  ? 316 SER B N   1 
ATOM   5589 C  CA  . SER B 1 316 ? 118.058 151.174 154.027 1.00 67.55  ? 316 SER B CA  1 
ATOM   5590 C  C   . SER B 1 316 ? 119.045 150.024 154.175 1.00 67.58  ? 316 SER B C   1 
ATOM   5591 O  O   . SER B 1 316 ? 120.225 150.201 153.857 1.00 64.74  ? 316 SER B O   1 
ATOM   5592 C  CB  . SER B 1 316 ? 118.434 152.294 154.998 1.00 70.40  ? 316 SER B CB  1 
ATOM   5593 O  OG  . SER B 1 316 ? 118.160 151.920 156.335 1.00 68.06  ? 316 SER B OG  1 
ATOM   5594 N  N   . HIS B 1 317 ? 118.601 148.866 154.650 1.00 65.00  ? 317 HIS B N   1 
ATOM   5595 C  CA  . HIS B 1 317 ? 119.505 147.741 154.824 1.00 61.14  ? 317 HIS B CA  1 
ATOM   5596 C  C   . HIS B 1 317 ? 119.887 147.160 153.465 1.00 62.20  ? 317 HIS B C   1 
ATOM   5597 O  O   . HIS B 1 317 ? 119.063 147.137 152.548 1.00 67.83  ? 317 HIS B O   1 
ATOM   5598 C  CB  . HIS B 1 317 ? 118.857 146.660 155.684 1.00 60.21  ? 317 HIS B CB  1 
ATOM   5599 C  CG  . HIS B 1 317 ? 119.834 145.693 156.271 1.00 64.53  ? 317 HIS B CG  1 
ATOM   5600 N  ND1 . HIS B 1 317 ? 120.048 144.439 155.742 1.00 66.00  ? 317 HIS B ND1 1 
ATOM   5601 C  CD2 . HIS B 1 317 ? 120.657 145.795 157.340 1.00 66.23  ? 317 HIS B CD2 1 
ATOM   5602 C  CE1 . HIS B 1 317 ? 120.962 143.811 156.459 1.00 63.74  ? 317 HIS B CE1 1 
ATOM   5603 N  NE2 . HIS B 1 317 ? 121.347 144.612 157.435 1.00 68.31  ? 317 HIS B NE2 1 
ATOM   5604 N  N   . PRO B 1 318 ? 121.124 146.685 153.303 1.00 54.87  ? 318 PRO B N   1 
ATOM   5605 C  CA  . PRO B 1 318 ? 121.513 146.081 152.021 1.00 52.67  ? 318 PRO B CA  1 
ATOM   5606 C  C   . PRO B 1 318 ? 120.692 144.866 151.648 1.00 54.42  ? 318 PRO B C   1 
ATOM   5607 O  O   . PRO B 1 318 ? 120.616 144.535 150.462 1.00 60.85  ? 318 PRO B O   1 
ATOM   5608 C  CB  . PRO B 1 318 ? 122.985 145.717 152.240 1.00 52.66  ? 318 PRO B CB  1 
ATOM   5609 C  CG  . PRO B 1 318 ? 123.444 146.655 153.284 1.00 58.16  ? 318 PRO B CG  1 
ATOM   5610 C  CD  . PRO B 1 318 ? 122.277 146.836 154.204 1.00 57.81  ? 318 PRO B CD  1 
ATOM   5611 N  N   . LEU B 1 319 ? 120.082 144.179 152.612 1.00 52.19  ? 319 LEU B N   1 
ATOM   5612 C  CA  . LEU B 1 319 ? 119.164 143.103 152.266 1.00 48.40  ? 319 LEU B CA  1 
ATOM   5613 C  C   . LEU B 1 319 ? 117.933 143.620 151.541 1.00 48.48  ? 319 LEU B C   1 
ATOM   5614 O  O   . LEU B 1 319 ? 117.238 142.836 150.889 1.00 53.92  ? 319 LEU B O   1 
ATOM   5615 C  CB  . LEU B 1 319 ? 118.736 142.342 153.521 1.00 52.36  ? 319 LEU B CB  1 
ATOM   5616 C  CG  . LEU B 1 319 ? 119.735 141.370 154.145 1.00 54.67  ? 319 LEU B CG  1 
ATOM   5617 C  CD1 . LEU B 1 319 ? 119.092 140.639 155.306 1.00 51.64  ? 319 LEU B CD1 1 
ATOM   5618 C  CD2 . LEU B 1 319 ? 120.240 140.388 153.112 1.00 55.48  ? 319 LEU B CD2 1 
ATOM   5619 N  N   . SER B 1 320 ? 117.651 144.918 151.638 1.00 56.27  ? 320 SER B N   1 
ATOM   5620 C  CA  . SER B 1 320 ? 116.461 145.503 151.032 1.00 56.24  ? 320 SER B CA  1 
ATOM   5621 C  C   . SER B 1 320 ? 116.744 146.027 149.628 1.00 57.51  ? 320 SER B C   1 
ATOM   5622 O  O   . SER B 1 320 ? 116.117 145.590 148.660 1.00 60.45  ? 320 SER B O   1 
ATOM   5623 C  CB  . SER B 1 320 ? 115.918 146.623 151.924 1.00 57.88  ? 320 SER B CB  1 
ATOM   5624 O  OG  . SER B 1 320 ? 115.003 147.437 151.214 1.00 63.96  ? 320 SER B OG  1 
ATOM   5625 N  N   . TRP B 1 321 ? 117.681 146.965 149.503 1.00 52.58  ? 321 TRP B N   1 
ATOM   5626 C  CA  . TRP B 1 321 ? 117.998 147.533 148.201 1.00 52.49  ? 321 TRP B CA  1 
ATOM   5627 C  C   . TRP B 1 321 ? 119.074 146.763 147.455 1.00 51.58  ? 321 TRP B C   1 
ATOM   5628 O  O   . TRP B 1 321 ? 119.215 146.949 146.244 1.00 59.58  ? 321 TRP B O   1 
ATOM   5629 C  CB  . TRP B 1 321 ? 118.424 148.996 148.342 1.00 51.28  ? 321 TRP B CB  1 
ATOM   5630 C  CG  . TRP B 1 321 ? 119.544 149.232 149.293 1.00 51.09  ? 321 TRP B CG  1 
ATOM   5631 C  CD1 . TRP B 1 321 ? 119.441 149.626 150.590 1.00 55.34  ? 321 TRP B CD1 1 
ATOM   5632 C  CD2 . TRP B 1 321 ? 120.944 149.115 149.019 1.00 54.71  ? 321 TRP B CD2 1 
ATOM   5633 N  NE1 . TRP B 1 321 ? 120.688 149.753 151.147 1.00 58.84  ? 321 TRP B NE1 1 
ATOM   5634 C  CE2 . TRP B 1 321 ? 121.629 149.445 150.201 1.00 53.33  ? 321 TRP B CE2 1 
ATOM   5635 C  CE3 . TRP B 1 321 ? 121.686 148.760 147.890 1.00 55.85  ? 321 TRP B CE3 1 
ATOM   5636 C  CZ2 . TRP B 1 321 ? 123.014 149.430 150.288 1.00 51.71  ? 321 TRP B CZ2 1 
ATOM   5637 C  CZ3 . TRP B 1 321 ? 123.061 148.746 147.979 1.00 54.74  ? 321 TRP B CZ3 1 
ATOM   5638 C  CH2 . TRP B 1 321 ? 123.711 149.077 149.168 1.00 55.05  ? 321 TRP B CH2 1 
ATOM   5639 N  N   . GLY B 1 322 ? 119.843 145.918 148.138 1.00 45.52  ? 322 GLY B N   1 
ATOM   5640 C  CA  . GLY B 1 322 ? 120.737 145.024 147.427 1.00 43.90  ? 322 GLY B CA  1 
ATOM   5641 C  C   . GLY B 1 322 ? 119.982 143.971 146.643 1.00 45.16  ? 322 GLY B C   1 
ATOM   5642 O  O   . GLY B 1 322 ? 120.391 143.588 145.546 1.00 51.49  ? 322 GLY B O   1 
ATOM   5643 N  N   . ARG B 1 323 ? 118.875 143.480 147.201 1.00 42.33  ? 323 ARG B N   1 
ATOM   5644 C  CA  . ARG B 1 323 ? 118.047 142.519 146.483 1.00 41.16  ? 323 ARG B CA  1 
ATOM   5645 C  C   . ARG B 1 323 ? 117.312 143.181 145.327 1.00 41.72  ? 323 ARG B C   1 
ATOM   5646 O  O   . ARG B 1 323 ? 117.141 142.577 144.265 1.00 43.83  ? 323 ARG B O   1 
ATOM   5647 C  CB  . ARG B 1 323 ? 117.054 141.865 147.441 1.00 37.89  ? 323 ARG B CB  1 
ATOM   5648 C  CG  . ARG B 1 323 ? 116.053 140.963 146.757 1.00 40.06  ? 323 ARG B CG  1 
ATOM   5649 C  CD  . ARG B 1 323 ? 114.958 140.514 147.700 1.00 39.31  ? 323 ARG B CD  1 
ATOM   5650 N  NE  . ARG B 1 323 ? 113.856 139.899 146.973 1.00 41.11  ? 323 ARG B NE  1 
ATOM   5651 C  CZ  . ARG B 1 323 ? 112.914 140.573 146.330 1.00 42.72  ? 323 ARG B CZ  1 
ATOM   5652 N  NH1 . ARG B 1 323 ? 112.887 141.893 146.331 1.00 46.05  ? 323 ARG B NH1 1 
ATOM   5653 N  NH2 . ARG B 1 323 ? 111.977 139.904 145.668 1.00 45.00  ? 323 ARG B NH2 1 
ATOM   5654 N  N   . ILE B 1 324 ? 116.867 144.422 145.518 1.00 47.77  ? 324 ILE B N   1 
ATOM   5655 C  CA  . ILE B 1 324 ? 116.130 145.123 144.473 1.00 44.00  ? 324 ILE B CA  1 
ATOM   5656 C  C   . ILE B 1 324 ? 117.034 145.423 143.285 1.00 47.30  ? 324 ILE B C   1 
ATOM   5657 O  O   . ILE B 1 324 ? 116.625 145.287 142.127 1.00 54.93  ? 324 ILE B O   1 
ATOM   5658 C  CB  . ILE B 1 324 ? 115.492 146.399 145.047 1.00 45.19  ? 324 ILE B CB  1 
ATOM   5659 C  CG1 . ILE B 1 324 ? 114.243 146.043 145.848 1.00 49.05  ? 324 ILE B CG1 1 
ATOM   5660 C  CG2 . ILE B 1 324 ? 115.134 147.357 143.943 1.00 49.24  ? 324 ILE B CG2 1 
ATOM   5661 C  CD1 . ILE B 1 324 ? 113.861 147.080 146.859 1.00 48.54  ? 324 ILE B CD1 1 
ATOM   5662 N  N   . LEU B 1 325 ? 118.275 145.838 143.547 1.00 45.89  ? 325 LEU B N   1 
ATOM   5663 C  CA  . LEU B 1 325 ? 119.223 146.061 142.461 1.00 42.95  ? 325 LEU B CA  1 
ATOM   5664 C  C   . LEU B 1 325 ? 119.505 144.771 141.705 1.00 46.92  ? 325 LEU B C   1 
ATOM   5665 O  O   . LEU B 1 325 ? 119.576 144.768 140.472 1.00 50.80  ? 325 LEU B O   1 
ATOM   5666 C  CB  . LEU B 1 325 ? 120.523 146.645 143.009 1.00 46.55  ? 325 LEU B CB  1 
ATOM   5667 C  CG  . LEU B 1 325 ? 120.522 148.097 143.480 1.00 49.26  ? 325 LEU B CG  1 
ATOM   5668 C  CD1 . LEU B 1 325 ? 121.850 148.428 144.123 1.00 50.00  ? 325 LEU B CD1 1 
ATOM   5669 C  CD2 . LEU B 1 325 ? 120.253 149.029 142.325 1.00 51.97  ? 325 LEU B CD2 1 
ATOM   5670 N  N   . PHE B 1 326 ? 119.679 143.666 142.429 1.00 41.27  ? 326 PHE B N   1 
ATOM   5671 C  CA  . PHE B 1 326 ? 119.992 142.399 141.779 1.00 38.89  ? 326 PHE B CA  1 
ATOM   5672 C  C   . PHE B 1 326 ? 118.815 141.882 140.960 1.00 42.63  ? 326 PHE B C   1 
ATOM   5673 O  O   . PHE B 1 326 ? 119.001 141.389 139.843 1.00 47.39  ? 326 PHE B O   1 
ATOM   5674 C  CB  . PHE B 1 326 ? 120.411 141.370 142.822 1.00 38.28  ? 326 PHE B CB  1 
ATOM   5675 C  CG  . PHE B 1 326 ? 120.372 139.964 142.323 1.00 41.30  ? 326 PHE B CG  1 
ATOM   5676 C  CD1 . PHE B 1 326 ? 121.219 139.554 141.311 1.00 38.92  ? 326 PHE B CD1 1 
ATOM   5677 C  CD2 . PHE B 1 326 ? 119.479 139.054 142.856 1.00 41.59  ? 326 PHE B CD2 1 
ATOM   5678 C  CE1 . PHE B 1 326 ? 121.178 138.267 140.847 1.00 37.47  ? 326 PHE B CE1 1 
ATOM   5679 C  CE2 . PHE B 1 326 ? 119.435 137.765 142.395 1.00 41.51  ? 326 PHE B CE2 1 
ATOM   5680 C  CZ  . PHE B 1 326 ? 120.286 137.370 141.392 1.00 45.93  ? 326 PHE B CZ  1 
ATOM   5681 N  N   . ILE B 1 327 ? 117.598 141.971 141.500 1.00 40.51  ? 327 ILE B N   1 
ATOM   5682 C  CA  . ILE B 1 327 ? 116.417 141.593 140.727 1.00 34.56  ? 327 ILE B CA  1 
ATOM   5683 C  C   . ILE B 1 327 ? 116.237 142.533 139.544 1.00 40.58  ? 327 ILE B C   1 
ATOM   5684 O  O   . ILE B 1 327 ? 115.784 142.118 138.473 1.00 50.73  ? 327 ILE B O   1 
ATOM   5685 C  CB  . ILE B 1 327 ? 115.172 141.565 141.636 1.00 34.97  ? 327 ILE B CB  1 
ATOM   5686 C  CG1 . ILE B 1 327 ? 115.294 140.452 142.673 1.00 35.04  ? 327 ILE B CG1 1 
ATOM   5687 C  CG2 . ILE B 1 327 ? 113.910 141.369 140.827 1.00 36.17  ? 327 ILE B CG2 1 
ATOM   5688 C  CD1 . ILE B 1 327 ? 115.082 139.073 142.115 1.00 44.03  ? 327 ILE B CD1 1 
ATOM   5689 N  N   . GLY B 1 328 ? 116.587 143.808 139.711 1.00 38.24  ? 328 GLY B N   1 
ATOM   5690 C  CA  . GLY B 1 328 ? 116.519 144.734 138.594 1.00 38.58  ? 328 GLY B CA  1 
ATOM   5691 C  C   . GLY B 1 328 ? 117.513 144.407 137.496 1.00 43.39  ? 328 GLY B C   1 
ATOM   5692 O  O   . GLY B 1 328 ? 117.218 144.577 136.312 1.00 42.78  ? 328 GLY B O   1 
ATOM   5693 N  N   . GLY B 1 329 ? 118.708 143.950 137.871 1.00 40.77  ? 329 GLY B N   1 
ATOM   5694 C  CA  . GLY B 1 329 ? 119.676 143.534 136.869 1.00 35.80  ? 329 GLY B CA  1 
ATOM   5695 C  C   . GLY B 1 329 ? 119.246 142.287 136.123 1.00 37.27  ? 329 GLY B C   1 
ATOM   5696 O  O   . GLY B 1 329 ? 119.502 142.151 134.926 1.00 45.88  ? 329 GLY B O   1 
ATOM   5697 N  N   . ILE B 1 330 ? 118.598 141.357 136.825 1.00 35.59  ? 330 ILE B N   1 
ATOM   5698 C  CA  . ILE B 1 330 ? 118.087 140.142 136.200 1.00 30.09  ? 330 ILE B CA  1 
ATOM   5699 C  C   . ILE B 1 330 ? 116.995 140.475 135.193 1.00 32.27  ? 330 ILE B C   1 
ATOM   5700 O  O   . ILE B 1 330 ? 116.860 139.817 134.156 1.00 34.68  ? 330 ILE B O   1 
ATOM   5701 C  CB  . ILE B 1 330 ? 117.562 139.187 137.284 1.00 34.08  ? 330 ILE B CB  1 
ATOM   5702 C  CG1 . ILE B 1 330 ? 118.671 138.330 137.869 1.00 39.13  ? 330 ILE B CG1 1 
ATOM   5703 C  CG2 . ILE B 1 330 ? 116.530 138.264 136.717 1.00 37.06  ? 330 ILE B CG2 1 
ATOM   5704 C  CD1 . ILE B 1 330 ? 118.116 137.229 138.739 1.00 43.00  ? 330 ILE B CD1 1 
ATOM   5705 N  N   . THR B 1 331 ? 116.190 141.496 135.492 1.00 31.15  ? 331 THR B N   1 
ATOM   5706 C  CA  . THR B 1 331 ? 114.994 141.782 134.708 1.00 23.58  ? 331 THR B CA  1 
ATOM   5707 C  C   . THR B 1 331 ? 115.326 142.178 133.276 1.00 30.17  ? 331 THR B C   1 
ATOM   5708 O  O   . THR B 1 331 ? 114.569 141.853 132.355 1.00 37.80  ? 331 THR B O   1 
ATOM   5709 C  CB  . THR B 1 331 ? 114.190 142.884 135.399 1.00 31.11  ? 331 THR B CB  1 
ATOM   5710 O  OG1 . THR B 1 331 ? 113.605 142.366 136.598 1.00 36.84  ? 331 THR B OG1 1 
ATOM   5711 C  CG2 . THR B 1 331 ? 113.096 143.413 134.502 1.00 36.66  ? 331 THR B CG2 1 
ATOM   5712 N  N   . ALA B 1 332 ? 116.449 142.859 133.062 1.00 25.77  ? 332 ALA B N   1 
ATOM   5713 C  CA  . ALA B 1 332 ? 116.771 143.345 131.721 1.00 22.98  ? 332 ALA B CA  1 
ATOM   5714 C  C   . ALA B 1 332 ? 116.915 142.226 130.696 1.00 26.26  ? 332 ALA B C   1 
ATOM   5715 O  O   . ALA B 1 332 ? 116.340 142.355 129.602 1.00 35.74  ? 332 ALA B O   1 
ATOM   5716 C  CB  . ALA B 1 332 ? 118.018 144.233 131.783 1.00 29.42  ? 332 ALA B CB  1 
ATOM   5717 N  N   . PRO B 1 333 ? 117.643 141.127 130.950 1.00 22.76  ? 333 PRO B N   1 
ATOM   5718 C  CA  . PRO B 1 333 ? 117.631 140.018 129.983 1.00 22.06  ? 333 PRO B CA  1 
ATOM   5719 C  C   . PRO B 1 333 ? 116.429 139.096 130.091 1.00 27.04  ? 333 PRO B C   1 
ATOM   5720 O  O   . PRO B 1 333 ? 116.188 138.323 129.158 1.00 36.64  ? 333 PRO B O   1 
ATOM   5721 C  CB  . PRO B 1 333 ? 118.924 139.260 130.301 1.00 21.40  ? 333 PRO B CB  1 
ATOM   5722 C  CG  . PRO B 1 333 ? 119.168 139.538 131.711 1.00 24.49  ? 333 PRO B CG  1 
ATOM   5723 C  CD  . PRO B 1 333 ? 118.714 140.943 131.945 1.00 22.86  ? 333 PRO B CD  1 
ATOM   5724 N  N   . THR B 1 334 ? 115.680 139.130 131.192 1.00 21.91  ? 334 THR B N   1 
ATOM   5725 C  CA  . THR B 1 334 ? 114.501 138.278 131.311 1.00 5.77   ? 334 THR B CA  1 
ATOM   5726 C  C   . THR B 1 334 ? 113.351 138.802 130.465 1.00 18.04  ? 334 THR B C   1 
ATOM   5727 O  O   . THR B 1 334 ? 112.629 138.021 129.838 1.00 38.96  ? 334 THR B O   1 
ATOM   5728 C  CB  . THR B 1 334 ? 114.074 138.177 132.770 1.00 19.13  ? 334 THR B CB  1 
ATOM   5729 O  OG1 . THR B 1 334 ? 115.079 137.482 133.513 1.00 29.45  ? 334 THR B OG1 1 
ATOM   5730 C  CG2 . THR B 1 334 ? 112.763 137.433 132.888 1.00 24.74  ? 334 THR B CG2 1 
ATOM   5731 N  N   . VAL B 1 335 ? 113.156 140.120 130.445 1.00 19.48  ? 335 VAL B N   1 
ATOM   5732 C  CA  . VAL B 1 335 ? 112.079 140.702 129.652 1.00 16.78  ? 335 VAL B CA  1 
ATOM   5733 C  C   . VAL B 1 335 ? 112.328 140.474 128.168 1.00 25.52  ? 335 VAL B C   1 
ATOM   5734 O  O   . VAL B 1 335 ? 111.391 140.261 127.391 1.00 40.32  ? 335 VAL B O   1 
ATOM   5735 C  CB  . VAL B 1 335 ? 111.928 142.196 129.983 1.00 16.97  ? 335 VAL B CB  1 
ATOM   5736 C  CG1 . VAL B 1 335 ? 110.951 142.856 129.041 1.00 31.97  ? 335 VAL B CG1 1 
ATOM   5737 C  CG2 . VAL B 1 335 ? 111.476 142.367 131.407 1.00 23.63  ? 335 VAL B CG2 1 
ATOM   5738 N  N   . ARG B 1 336 ? 113.590 140.508 127.749 1.00 25.28  ? 336 ARG B N   1 
ATOM   5739 C  CA  . ARG B 1 336 ? 113.931 140.318 126.349 1.00 26.21  ? 336 ARG B CA  1 
ATOM   5740 C  C   . ARG B 1 336 ? 113.951 138.855 125.932 1.00 24.14  ? 336 ARG B C   1 
ATOM   5741 O  O   . ARG B 1 336 ? 113.979 138.574 124.732 1.00 35.27  ? 336 ARG B O   1 
ATOM   5742 C  CB  . ARG B 1 336 ? 115.286 140.957 126.057 1.00 29.98  ? 336 ARG B CB  1 
ATOM   5743 C  CG  . ARG B 1 336 ? 115.246 142.470 126.010 1.00 22.98  ? 336 ARG B CG  1 
ATOM   5744 C  CD  . ARG B 1 336 ? 115.202 142.962 124.579 1.00 31.42  ? 336 ARG B CD  1 
ATOM   5745 N  NE  . ARG B 1 336 ? 115.091 144.412 124.493 1.00 29.82  ? 336 ARG B NE  1 
ATOM   5746 C  CZ  . ARG B 1 336 ? 113.940 145.065 124.449 1.00 37.39  ? 336 ARG B CZ  1 
ATOM   5747 N  NH1 . ARG B 1 336 ? 112.784 144.426 124.491 1.00 43.94  ? 336 ARG B NH1 1 
ATOM   5748 N  NH2 . ARG B 1 336 ? 113.949 146.390 124.357 1.00 38.05  ? 336 ARG B NH2 1 
ATOM   5749 N  N   . GLN B 1 337 ? 113.940 137.925 126.883 1.00 22.21  ? 337 GLN B N   1 
ATOM   5750 C  CA  . GLN B 1 337 ? 113.855 136.501 126.591 1.00 16.36  ? 337 GLN B CA  1 
ATOM   5751 C  C   . GLN B 1 337 ? 112.443 135.957 126.700 1.00 19.93  ? 337 GLN B C   1 
ATOM   5752 O  O   . GLN B 1 337 ? 112.116 134.978 126.027 1.00 29.66  ? 337 GLN B O   1 
ATOM   5753 C  CB  . GLN B 1 337 ? 114.757 135.710 127.536 1.00 16.82  ? 337 GLN B CB  1 
ATOM   5754 C  CG  . GLN B 1 337 ? 116.216 135.799 127.212 1.00 14.30  ? 337 GLN B CG  1 
ATOM   5755 C  CD  . GLN B 1 337 ? 117.026 134.875 128.062 1.00 17.54  ? 337 GLN B CD  1 
ATOM   5756 O  OE1 . GLN B 1 337 ? 116.512 134.281 128.997 1.00 33.79  ? 337 GLN B OE1 1 
ATOM   5757 N  NE2 . GLN B 1 337 ? 118.297 134.736 127.743 1.00 21.32  ? 337 GLN B NE2 1 
ATOM   5758 N  N   . TYR B 1 338 ? 111.613 136.545 127.559 1.00 29.26  ? 338 TYR B N   1 
ATOM   5759 C  CA  . TYR B 1 338 ? 110.200 136.191 127.579 1.00 24.40  ? 338 TYR B CA  1 
ATOM   5760 C  C   . TYR B 1 338 ? 109.487 136.752 126.361 1.00 33.21  ? 338 TYR B C   1 
ATOM   5761 O  O   . TYR B 1 338 ? 108.586 136.110 125.813 1.00 46.12  ? 338 TYR B O   1 
ATOM   5762 C  CB  . TYR B 1 338 ? 109.548 136.698 128.863 1.00 31.28  ? 338 TYR B CB  1 
ATOM   5763 C  CG  . TYR B 1 338 ? 108.118 136.249 129.056 1.00 33.81  ? 338 TYR B CG  1 
ATOM   5764 C  CD1 . TYR B 1 338 ? 107.072 136.912 128.442 1.00 32.45  ? 338 TYR B CD1 1 
ATOM   5765 C  CD2 . TYR B 1 338 ? 107.815 135.173 129.865 1.00 35.58  ? 338 TYR B CD2 1 
ATOM   5766 C  CE1 . TYR B 1 338 ? 105.775 136.510 128.618 1.00 32.73  ? 338 TYR B CE1 1 
ATOM   5767 C  CE2 . TYR B 1 338 ? 106.520 134.771 130.050 1.00 32.93  ? 338 TYR B CE2 1 
ATOM   5768 C  CZ  . TYR B 1 338 ? 105.505 135.440 129.420 1.00 34.62  ? 338 TYR B CZ  1 
ATOM   5769 O  OH  . TYR B 1 338 ? 104.205 135.040 129.596 1.00 46.12  ? 338 TYR B OH  1 
ATOM   5770 N  N   . TYR B 1 339 ? 109.860 137.959 125.933 1.00 29.91  ? 339 TYR B N   1 
ATOM   5771 C  CA  . TYR B 1 339 ? 109.281 138.515 124.718 1.00 26.34  ? 339 TYR B CA  1 
ATOM   5772 C  C   . TYR B 1 339 ? 109.665 137.690 123.502 1.00 33.49  ? 339 TYR B C   1 
ATOM   5773 O  O   . TYR B 1 339 ? 108.834 137.448 122.622 1.00 49.35  ? 339 TYR B O   1 
ATOM   5774 C  CB  . TYR B 1 339 ? 109.720 139.963 124.531 1.00 29.30  ? 339 TYR B CB  1 
ATOM   5775 C  CG  . TYR B 1 339 ? 109.336 140.524 123.184 1.00 38.57  ? 339 TYR B CG  1 
ATOM   5776 C  CD1 . TYR B 1 339 ? 108.022 140.860 122.901 1.00 40.08  ? 339 TYR B CD1 1 
ATOM   5777 C  CD2 . TYR B 1 339 ? 110.283 140.708 122.194 1.00 39.61  ? 339 TYR B CD2 1 
ATOM   5778 C  CE1 . TYR B 1 339 ? 107.666 141.369 121.677 1.00 33.39  ? 339 TYR B CE1 1 
ATOM   5779 C  CE2 . TYR B 1 339 ? 109.933 141.213 120.966 1.00 37.13  ? 339 TYR B CE2 1 
ATOM   5780 C  CZ  . TYR B 1 339 ? 108.624 141.539 120.712 1.00 36.88  ? 339 TYR B CZ  1 
ATOM   5781 O  OH  . TYR B 1 339 ? 108.273 142.045 119.485 1.00 44.46  ? 339 TYR B OH  1 
ATOM   5782 N  N   . ALA B 1 340 ? 110.920 137.254 123.429 1.00 25.48  ? 340 ALA B N   1 
ATOM   5783 C  CA  . ALA B 1 340 ? 111.365 136.482 122.276 1.00 18.94  ? 340 ALA B CA  1 
ATOM   5784 C  C   . ALA B 1 340 ? 110.643 135.144 122.195 1.00 22.24  ? 340 ALA B C   1 
ATOM   5785 O  O   . ALA B 1 340 ? 110.191 134.736 121.122 1.00 38.08  ? 340 ALA B O   1 
ATOM   5786 C  CB  . ALA B 1 340 ? 112.875 136.280 122.336 1.00 26.43  ? 340 ALA B CB  1 
ATOM   5787 N  N   . TYR B 1 341 ? 110.524 134.445 123.325 1.00 31.62  ? 341 TYR B N   1 
ATOM   5788 C  CA  . TYR B 1 341 ? 109.817 133.168 123.333 1.00 29.29  ? 341 TYR B CA  1 
ATOM   5789 C  C   . TYR B 1 341 ? 108.341 133.350 123.015 1.00 30.60  ? 341 TYR B C   1 
ATOM   5790 O  O   . TYR B 1 341 ? 107.762 132.568 122.257 1.00 36.48  ? 341 TYR B O   1 
ATOM   5791 C  CB  . TYR B 1 341 ? 109.984 132.484 124.688 1.00 28.09  ? 341 TYR B CB  1 
ATOM   5792 C  CG  . TYR B 1 341 ? 109.218 131.191 124.826 1.00 33.25  ? 341 TYR B CG  1 
ATOM   5793 C  CD1 . TYR B 1 341 ? 109.720 130.009 124.313 1.00 34.66  ? 341 TYR B CD1 1 
ATOM   5794 C  CD2 . TYR B 1 341 ? 107.998 131.149 125.477 1.00 39.53  ? 341 TYR B CD2 1 
ATOM   5795 C  CE1 . TYR B 1 341 ? 109.027 128.826 124.438 1.00 39.07  ? 341 TYR B CE1 1 
ATOM   5796 C  CE2 . TYR B 1 341 ? 107.298 129.968 125.602 1.00 38.87  ? 341 TYR B CE2 1 
ATOM   5797 C  CZ  . TYR B 1 341 ? 107.820 128.812 125.080 1.00 39.38  ? 341 TYR B CZ  1 
ATOM   5798 O  OH  . TYR B 1 341 ? 107.134 127.631 125.202 1.00 43.65  ? 341 TYR B OH  1 
ATOM   5799 N  N   . LEU B 1 342 ? 107.716 134.376 123.587 1.00 29.04  ? 342 LEU B N   1 
ATOM   5800 C  CA  . LEU B 1 342 ? 106.274 134.539 123.449 1.00 33.86  ? 342 LEU B CA  1 
ATOM   5801 C  C   . LEU B 1 342 ? 105.868 134.814 122.005 1.00 43.94  ? 342 LEU B C   1 
ATOM   5802 O  O   . LEU B 1 342 ? 104.866 134.272 121.526 1.00 47.57  ? 342 LEU B O   1 
ATOM   5803 C  CB  . LEU B 1 342 ? 105.795 135.659 124.370 1.00 32.36  ? 342 LEU B CB  1 
ATOM   5804 C  CG  . LEU B 1 342 ? 104.477 136.341 124.027 1.00 41.66  ? 342 LEU B CG  1 
ATOM   5805 C  CD1 . LEU B 1 342 ? 103.323 135.517 124.544 1.00 41.07  ? 342 LEU B CD1 1 
ATOM   5806 C  CD2 . LEU B 1 342 ? 104.440 137.742 124.599 1.00 40.42  ? 342 LEU B CD2 1 
ATOM   5807 N  N   . THR B 1 343 ? 106.630 135.643 121.294 1.00 42.34  ? 343 THR B N   1 
ATOM   5808 C  CA  . THR B 1 343 ? 106.228 136.075 119.961 1.00 37.83  ? 343 THR B CA  1 
ATOM   5809 C  C   . THR B 1 343 ? 106.839 135.227 118.852 1.00 47.08  ? 343 THR B C   1 
ATOM   5810 O  O   . THR B 1 343 ? 106.112 134.715 117.996 1.00 55.83  ? 343 THR B O   1 
ATOM   5811 C  CB  . THR B 1 343 ? 106.601 137.540 119.748 1.00 36.67  ? 343 THR B CB  1 
ATOM   5812 O  OG1 . THR B 1 343 ? 108.001 137.640 119.477 1.00 36.05  ? 343 THR B OG1 1 
ATOM   5813 C  CG2 . THR B 1 343 ? 106.271 138.340 120.980 1.00 42.12  ? 343 THR B CG2 1 
ATOM   5814 N  N   . ASP B 1 344 ? 108.163 135.085 118.839 1.00 49.78  ? 344 ASP B N   1 
ATOM   5815 C  CA  . ASP B 1 344 ? 108.823 134.329 117.782 1.00 45.86  ? 344 ASP B CA  1 
ATOM   5816 C  C   . ASP B 1 344 ? 108.310 132.898 117.755 1.00 50.62  ? 344 ASP B C   1 
ATOM   5817 O  O   . ASP B 1 344 ? 108.247 132.231 118.789 1.00 53.19  ? 344 ASP B O   1 
ATOM   5818 C  CB  . ASP B 1 344 ? 110.334 134.342 117.987 1.00 46.20  ? 344 ASP B CB  1 
ATOM   5819 C  CG  . ASP B 1 344 ? 111.093 134.651 116.715 1.00 59.05  ? 344 ASP B CG  1 
ATOM   5820 O  OD1 . ASP B 1 344 ? 110.700 134.144 115.645 1.00 61.75  ? 344 ASP B OD1 1 
ATOM   5821 O  OD2 . ASP B 1 344 ? 112.088 135.401 116.785 1.00 60.90  ? 344 ASP B OD2 1 
ATOM   5822 N  N   . THR B 1 345 ? 107.939 132.429 116.568 1.00 59.63  ? 345 THR B N   1 
ATOM   5823 C  CA  . THR B 1 345 ? 107.364 131.101 116.417 1.00 61.98  ? 345 THR B CA  1 
ATOM   5824 C  C   . THR B 1 345 ? 108.405 130.027 116.139 1.00 62.46  ? 345 THR B C   1 
ATOM   5825 O  O   . THR B 1 345 ? 108.054 128.844 116.098 1.00 63.17  ? 345 THR B O   1 
ATOM   5826 C  CB  . THR B 1 345 ? 106.321 131.099 115.297 1.00 57.25  ? 345 THR B CB  1 
ATOM   5827 O  OG1 . THR B 1 345 ? 105.530 129.908 115.382 1.00 60.80  ? 345 THR B OG1 1 
ATOM   5828 C  CG2 . THR B 1 345 ? 106.998 131.152 113.944 1.00 57.17  ? 345 THR B CG2 1 
ATOM   5829 N  N   . GLN B 1 346 ? 109.666 130.404 115.953 1.00 62.65  ? 346 GLN B N   1 
ATOM   5830 C  CA  . GLN B 1 346 ? 110.745 129.455 115.733 1.00 59.96  ? 346 GLN B CA  1 
ATOM   5831 C  C   . GLN B 1 346 ? 111.625 129.280 116.958 1.00 65.73  ? 346 GLN B C   1 
ATOM   5832 O  O   . GLN B 1 346 ? 112.714 128.710 116.847 1.00 71.01  ? 346 GLN B O   1 
ATOM   5833 C  CB  . GLN B 1 346 ? 111.603 129.893 114.547 1.00 61.57  ? 346 GLN B CB  1 
ATOM   5834 C  CG  . GLN B 1 346 ? 110.820 130.304 113.317 1.00 67.56  ? 346 GLN B CG  1 
ATOM   5835 C  CD  . GLN B 1 346 ? 111.682 131.032 112.307 1.00 70.58  ? 346 GLN B CD  1 
ATOM   5836 O  OE1 . GLN B 1 346 ? 112.683 130.499 111.830 1.00 71.60  ? 346 GLN B OE1 1 
ATOM   5837 N  NE2 . GLN B 1 346 ? 111.301 132.260 111.979 1.00 69.12  ? 346 GLN B NE2 1 
ATOM   5838 N  N   . CYS B 1 347 ? 111.188 129.762 118.121 1.00 53.48  ? 347 CYS B N   1 
ATOM   5839 C  CA  . CYS B 1 347 ? 112.035 129.715 119.307 1.00 52.84  ? 347 CYS B CA  1 
ATOM   5840 C  C   . CYS B 1 347 ? 111.983 128.347 119.977 1.00 52.70  ? 347 CYS B C   1 
ATOM   5841 O  O   . CYS B 1 347 ? 113.009 127.674 120.117 1.00 55.80  ? 347 CYS B O   1 
ATOM   5842 C  CB  . CYS B 1 347 ? 111.630 130.820 120.279 1.00 44.78  ? 347 CYS B CB  1 
ATOM   5843 S  SG  . CYS B 1 347 ? 112.536 132.352 120.016 1.00 54.41  ? 347 CYS B SG  1 
ATOM   5844 N  N   . LYS B 1 348 ? 110.796 127.930 120.410 1.00 43.74  ? 348 LYS B N   1 
ATOM   5845 C  CA  . LYS B 1 348 ? 110.545 126.582 120.917 1.00 46.21  ? 348 LYS B CA  1 
ATOM   5846 C  C   . LYS B 1 348 ? 111.343 126.254 122.176 1.00 45.18  ? 348 LYS B C   1 
ATOM   5847 O  O   . LYS B 1 348 ? 111.485 125.082 122.524 1.00 49.59  ? 348 LYS B O   1 
ATOM   5848 C  CB  . LYS B 1 348 ? 110.820 125.526 119.840 1.00 49.05  ? 348 LYS B CB  1 
ATOM   5849 C  CG  . LYS B 1 348 ? 109.878 125.579 118.653 1.00 49.39  ? 348 LYS B CG  1 
ATOM   5850 C  CD  . LYS B 1 348 ? 108.437 125.410 119.085 1.00 51.63  ? 348 LYS B CD  1 
ATOM   5851 C  CE  . LYS B 1 348 ? 107.498 125.481 117.897 1.00 50.93  ? 348 LYS B CE  1 
ATOM   5852 N  NZ  . LYS B 1 348 ? 107.767 126.672 117.048 1.00 52.88  ? 348 LYS B NZ  1 
ATOM   5853 N  N   . ARG B 1 349 ? 111.883 127.259 122.864 1.00 41.93  ? 349 ARG B N   1 
ATOM   5854 C  CA  . ARG B 1 349 ? 112.492 127.053 124.172 1.00 34.28  ? 349 ARG B CA  1 
ATOM   5855 C  C   . ARG B 1 349 ? 112.622 128.397 124.869 1.00 34.82  ? 349 ARG B C   1 
ATOM   5856 O  O   . ARG B 1 349 ? 112.906 129.407 124.225 1.00 44.56  ? 349 ARG B O   1 
ATOM   5857 C  CB  . ARG B 1 349 ? 113.861 126.376 124.082 1.00 33.78  ? 349 ARG B CB  1 
ATOM   5858 C  CG  . ARG B 1 349 ? 114.164 125.530 125.300 1.00 36.48  ? 349 ARG B CG  1 
ATOM   5859 C  CD  . ARG B 1 349 ? 115.597 125.056 125.355 1.00 37.70  ? 349 ARG B CD  1 
ATOM   5860 N  NE  . ARG B 1 349 ? 116.033 124.884 126.734 1.00 42.34  ? 349 ARG B NE  1 
ATOM   5861 C  CZ  . ARG B 1 349 ? 117.270 124.588 127.099 1.00 41.86  ? 349 ARG B CZ  1 
ATOM   5862 N  NH1 . ARG B 1 349 ? 118.224 124.395 126.209 1.00 40.34  ? 349 ARG B NH1 1 
ATOM   5863 N  NH2 . ARG B 1 349 ? 117.559 124.491 128.392 1.00 38.45  ? 349 ARG B NH2 1 
ATOM   5864 N  N   . VAL B 1 350 ? 112.414 128.396 126.181 1.00 30.62  ? 350 VAL B N   1 
ATOM   5865 C  CA  . VAL B 1 350 ? 112.456 129.615 126.980 1.00 37.39  ? 350 VAL B CA  1 
ATOM   5866 C  C   . VAL B 1 350 ? 113.848 129.765 127.577 1.00 35.30  ? 350 VAL B C   1 
ATOM   5867 O  O   . VAL B 1 350 ? 114.412 128.804 128.112 1.00 42.67  ? 350 VAL B O   1 
ATOM   5868 C  CB  . VAL B 1 350 ? 111.369 129.598 128.070 1.00 31.87  ? 350 VAL B CB  1 
ATOM   5869 C  CG1 . VAL B 1 350 ? 111.515 128.396 128.969 1.00 30.39  ? 350 VAL B CG1 1 
ATOM   5870 C  CG2 . VAL B 1 350 ? 111.403 130.878 128.876 1.00 33.99  ? 350 VAL B CG2 1 
ATOM   5871 N  N   . GLY B 1 351 ? 114.411 130.965 127.465 1.00 27.77  ? 351 GLY B N   1 
ATOM   5872 C  CA  . GLY B 1 351 ? 115.793 131.170 127.849 1.00 28.17  ? 351 GLY B CA  1 
ATOM   5873 C  C   . GLY B 1 351 ? 116.044 130.819 129.299 1.00 26.65  ? 351 GLY B C   1 
ATOM   5874 O  O   . GLY B 1 351 ? 115.144 130.819 130.134 1.00 34.48  ? 351 GLY B O   1 
ATOM   5875 N  N   . THR B 1 352 ? 117.303 130.495 129.594 1.00 26.39  ? 352 THR B N   1 
ATOM   5876 C  CA  . THR B 1 352 ? 117.635 130.007 130.927 1.00 24.47  ? 352 THR B CA  1 
ATOM   5877 C  C   . THR B 1 352 ? 117.509 131.107 131.974 1.00 32.12  ? 352 THR B C   1 
ATOM   5878 O  O   . THR B 1 352 ? 117.085 130.844 133.103 1.00 36.60  ? 352 THR B O   1 
ATOM   5879 C  CB  . THR B 1 352 ? 119.038 129.410 130.940 1.00 26.73  ? 352 THR B CB  1 
ATOM   5880 O  OG1 . THR B 1 352 ? 119.219 128.605 129.771 1.00 35.50  ? 352 THR B OG1 1 
ATOM   5881 C  CG2 . THR B 1 352 ? 119.209 128.534 132.156 1.00 21.39  ? 352 THR B CG2 1 
ATOM   5882 N  N   . GLN B 1 353 ? 117.873 132.342 131.628 1.00 30.16  ? 353 GLN B N   1 
ATOM   5883 C  CA  . GLN B 1 353 ? 117.703 133.441 132.573 1.00 17.53  ? 353 GLN B CA  1 
ATOM   5884 C  C   . GLN B 1 353 ? 116.231 133.684 132.875 1.00 23.09  ? 353 GLN B C   1 
ATOM   5885 O  O   . GLN B 1 353 ? 115.866 133.993 134.013 1.00 30.46  ? 353 GLN B O   1 
ATOM   5886 C  CB  . GLN B 1 353 ? 118.353 134.709 132.034 1.00 21.69  ? 353 GLN B CB  1 
ATOM   5887 C  CG  . GLN B 1 353 ? 118.160 135.914 132.922 1.00 20.44  ? 353 GLN B CG  1 
ATOM   5888 C  CD  . GLN B 1 353 ? 119.085 135.912 134.110 1.00 28.07  ? 353 GLN B CD  1 
ATOM   5889 O  OE1 . GLN B 1 353 ? 118.870 135.189 135.079 1.00 27.58  ? 353 GLN B OE1 1 
ATOM   5890 N  NE2 . GLN B 1 353 ? 120.126 136.726 134.044 1.00 35.18  ? 353 GLN B NE2 1 
ATOM   5891 N  N   . CYS B 1 354 ? 115.372 133.565 131.863 1.00 23.25  ? 354 CYS B N   1 
ATOM   5892 C  CA  . CYS B 1 354 ? 113.937 133.662 132.097 1.00 18.89  ? 354 CYS B CA  1 
ATOM   5893 C  C   . CYS B 1 354 ? 113.426 132.493 132.929 1.00 26.36  ? 354 CYS B C   1 
ATOM   5894 O  O   . CYS B 1 354 ? 112.488 132.658 133.714 1.00 38.40  ? 354 CYS B O   1 
ATOM   5895 C  CB  . CYS B 1 354 ? 113.199 133.736 130.764 1.00 18.63  ? 354 CYS B CB  1 
ATOM   5896 S  SG  . CYS B 1 354 ? 111.429 133.985 130.890 1.00 47.72  ? 354 CYS B SG  1 
ATOM   5897 N  N   . TRP B 1 355 ? 114.017 131.308 132.765 1.00 24.89  ? 355 TRP B N   1 
ATOM   5898 C  CA  . TRP B 1 355 ? 113.667 130.173 133.611 1.00 17.38  ? 355 TRP B CA  1 
ATOM   5899 C  C   . TRP B 1 355 ? 114.048 130.439 135.061 1.00 21.91  ? 355 TRP B C   1 
ATOM   5900 O  O   . TRP B 1 355 ? 113.266 130.179 135.980 1.00 28.42  ? 355 TRP B O   1 
ATOM   5901 C  CB  . TRP B 1 355 ? 114.358 128.912 133.092 1.00 18.12  ? 355 TRP B CB  1 
ATOM   5902 C  CG  . TRP B 1 355 ? 113.866 127.622 133.683 1.00 26.99  ? 355 TRP B CG  1 
ATOM   5903 C  CD1 . TRP B 1 355 ? 112.945 126.777 133.143 1.00 27.89  ? 355 TRP B CD1 1 
ATOM   5904 C  CD2 . TRP B 1 355 ? 114.285 127.021 134.915 1.00 27.52  ? 355 TRP B CD2 1 
ATOM   5905 N  NE1 . TRP B 1 355 ? 112.757 125.695 133.965 1.00 28.30  ? 355 TRP B NE1 1 
ATOM   5906 C  CE2 . TRP B 1 355 ? 113.570 125.822 135.059 1.00 25.36  ? 355 TRP B CE2 1 
ATOM   5907 C  CE3 . TRP B 1 355 ? 115.191 127.385 135.913 1.00 29.23  ? 355 TRP B CE3 1 
ATOM   5908 C  CZ2 . TRP B 1 355 ? 113.732 124.988 136.157 1.00 28.05  ? 355 TRP B CZ2 1 
ATOM   5909 C  CZ3 . TRP B 1 355 ? 115.348 126.555 137.000 1.00 19.10  ? 355 TRP B CZ3 1 
ATOM   5910 C  CH2 . TRP B 1 355 ? 114.625 125.372 137.114 1.00 22.67  ? 355 TRP B CH2 1 
ATOM   5911 N  N   . VAL B 1 356 ? 115.253 130.967 135.283 1.00 24.31  ? 356 VAL B N   1 
ATOM   5912 C  CA  . VAL B 1 356 ? 115.729 131.203 136.642 1.00 18.03  ? 356 VAL B CA  1 
ATOM   5913 C  C   . VAL B 1 356 ? 114.964 132.346 137.296 1.00 30.07  ? 356 VAL B C   1 
ATOM   5914 O  O   . VAL B 1 356 ? 114.662 132.297 138.492 1.00 43.16  ? 356 VAL B O   1 
ATOM   5915 C  CB  . VAL B 1 356 ? 117.245 131.457 136.641 1.00 16.05  ? 356 VAL B CB  1 
ATOM   5916 C  CG1 . VAL B 1 356 ? 117.704 131.827 138.018 1.00 26.81  ? 356 VAL B CG1 1 
ATOM   5917 C  CG2 . VAL B 1 356 ? 117.977 130.224 136.173 1.00 21.28  ? 356 VAL B CG2 1 
ATOM   5918 N  N   . PHE B 1 357 ? 114.641 133.397 136.542 1.00 27.17  ? 357 PHE B N   1 
ATOM   5919 C  CA  . PHE B 1 357 ? 113.777 134.434 137.095 1.00 26.81  ? 357 PHE B CA  1 
ATOM   5920 C  C   . PHE B 1 357 ? 112.369 133.917 137.361 1.00 33.31  ? 357 PHE B C   1 
ATOM   5921 O  O   . PHE B 1 357 ? 111.606 134.567 138.080 1.00 38.07  ? 357 PHE B O   1 
ATOM   5922 C  CB  . PHE B 1 357 ? 113.724 135.642 136.163 1.00 25.46  ? 357 PHE B CB  1 
ATOM   5923 C  CG  . PHE B 1 357 ? 112.936 136.801 136.712 1.00 28.75  ? 357 PHE B CG  1 
ATOM   5924 C  CD1 . PHE B 1 357 ? 113.468 137.616 137.686 1.00 31.20  ? 357 PHE B CD1 1 
ATOM   5925 C  CD2 . PHE B 1 357 ? 111.666 137.073 136.252 1.00 33.46  ? 357 PHE B CD2 1 
ATOM   5926 C  CE1 . PHE B 1 357 ? 112.757 138.679 138.186 1.00 31.68  ? 357 PHE B CE1 1 
ATOM   5927 C  CE2 . PHE B 1 357 ? 110.949 138.135 136.758 1.00 32.75  ? 357 PHE B CE2 1 
ATOM   5928 C  CZ  . PHE B 1 357 ? 111.498 138.937 137.722 1.00 32.90  ? 357 PHE B CZ  1 
ATOM   5929 N  N   . GLY B 1 358 ? 112.012 132.764 136.807 1.00 31.00  ? 358 GLY B N   1 
ATOM   5930 C  CA  . GLY B 1 358 ? 110.733 132.152 137.091 1.00 23.24  ? 358 GLY B CA  1 
ATOM   5931 C  C   . GLY B 1 358 ? 110.702 131.454 138.433 1.00 28.54  ? 358 GLY B C   1 
ATOM   5932 O  O   . GLY B 1 358 ? 109.750 131.628 139.194 1.00 37.55  ? 358 GLY B O   1 
ATOM   5933 N  N   . VAL B 1 359 ? 111.725 130.650 138.734 1.00 28.82  ? 359 VAL B N   1 
ATOM   5934 C  CA  . VAL B 1 359 ? 111.784 129.994 140.036 1.00 23.60  ? 359 VAL B CA  1 
ATOM   5935 C  C   . VAL B 1 359 ? 111.995 131.016 141.143 1.00 31.88  ? 359 VAL B C   1 
ATOM   5936 O  O   . VAL B 1 359 ? 111.360 130.941 142.199 1.00 37.98  ? 359 VAL B O   1 
ATOM   5937 C  CB  . VAL B 1 359 ? 112.874 128.907 140.057 1.00 19.39  ? 359 VAL B CB  1 
ATOM   5938 C  CG1 . VAL B 1 359 ? 112.401 127.671 139.352 1.00 23.07  ? 359 VAL B CG1 1 
ATOM   5939 C  CG2 . VAL B 1 359 ? 114.128 129.404 139.404 1.00 29.92  ? 359 VAL B CG2 1 
ATOM   5940 N  N   . ILE B 1 360 ? 112.879 131.990 140.922 1.00 33.29  ? 360 ILE B N   1 
ATOM   5941 C  CA  . ILE B 1 360 ? 113.174 132.978 141.956 1.00 27.27  ? 360 ILE B CA  1 
ATOM   5942 C  C   . ILE B 1 360 ? 111.912 133.732 142.350 1.00 33.15  ? 360 ILE B C   1 
ATOM   5943 O  O   . ILE B 1 360 ? 111.639 133.934 143.537 1.00 39.19  ? 360 ILE B O   1 
ATOM   5944 C  CB  . ILE B 1 360 ? 114.278 133.936 141.476 1.00 23.00  ? 360 ILE B CB  1 
ATOM   5945 C  CG1 . ILE B 1 360 ? 115.611 133.203 141.370 1.00 20.20  ? 360 ILE B CG1 1 
ATOM   5946 C  CG2 . ILE B 1 360 ? 114.409 135.111 142.415 1.00 29.65  ? 360 ILE B CG2 1 
ATOM   5947 C  CD1 . ILE B 1 360 ? 116.753 134.095 140.997 1.00 22.24  ? 360 ILE B CD1 1 
ATOM   5948 N  N   . GLY B 1 361 ? 111.122 134.156 141.363 1.00 30.76  ? 361 GLY B N   1 
ATOM   5949 C  CA  . GLY B 1 361 ? 109.885 134.856 141.660 1.00 27.51  ? 361 GLY B CA  1 
ATOM   5950 C  C   . GLY B 1 361 ? 108.846 133.985 142.334 1.00 27.19  ? 361 GLY B C   1 
ATOM   5951 O  O   . GLY B 1 361 ? 108.084 134.465 143.175 1.00 29.13  ? 361 GLY B O   1 
ATOM   5952 N  N   . PHE B 1 362 ? 108.786 132.707 141.964 1.00 31.71  ? 362 PHE B N   1 
ATOM   5953 C  CA  . PHE B 1 362 ? 107.819 131.792 142.560 1.00 33.59  ? 362 PHE B CA  1 
ATOM   5954 C  C   . PHE B 1 362 ? 108.281 131.290 143.922 1.00 37.73  ? 362 PHE B C   1 
ATOM   5955 O  O   . PHE B 1 362 ? 107.461 131.111 144.826 1.00 38.28  ? 362 PHE B O   1 
ATOM   5956 C  CB  . PHE B 1 362 ? 107.574 130.609 141.628 1.00 28.66  ? 362 PHE B CB  1 
ATOM   5957 C  CG  . PHE B 1 362 ? 106.457 130.820 140.652 1.00 31.54  ? 362 PHE B CG  1 
ATOM   5958 C  CD1 . PHE B 1 362 ? 105.151 130.921 141.089 1.00 37.19  ? 362 PHE B CD1 1 
ATOM   5959 C  CD2 . PHE B 1 362 ? 106.712 130.895 139.298 1.00 31.80  ? 362 PHE B CD2 1 
ATOM   5960 C  CE1 . PHE B 1 362 ? 104.124 131.110 140.194 1.00 32.23  ? 362 PHE B CE1 1 
ATOM   5961 C  CE2 . PHE B 1 362 ? 105.690 131.084 138.401 1.00 34.85  ? 362 PHE B CE2 1 
ATOM   5962 C  CZ  . PHE B 1 362 ? 104.393 131.190 138.850 1.00 29.73  ? 362 PHE B CZ  1 
ATOM   5963 N  N   . LEU B 1 363 ? 109.584 131.041 144.081 1.00 34.89  ? 363 LEU B N   1 
ATOM   5964 C  CA  . LEU B 1 363 ? 110.096 130.552 145.358 1.00 28.24  ? 363 LEU B CA  1 
ATOM   5965 C  C   . LEU B 1 363 ? 110.019 131.622 146.435 1.00 27.87  ? 363 LEU B C   1 
ATOM   5966 O  O   . LEU B 1 363 ? 109.787 131.311 147.606 1.00 37.45  ? 363 LEU B O   1 
ATOM   5967 C  CB  . LEU B 1 363 ? 111.534 130.067 145.203 1.00 25.58  ? 363 LEU B CB  1 
ATOM   5968 C  CG  . LEU B 1 363 ? 111.709 128.710 144.535 1.00 28.56  ? 363 LEU B CG  1 
ATOM   5969 C  CD1 . LEU B 1 363 ? 113.111 128.204 144.743 1.00 27.44  ? 363 LEU B CD1 1 
ATOM   5970 C  CD2 . LEU B 1 363 ? 110.700 127.737 145.090 1.00 31.26  ? 363 LEU B CD2 1 
ATOM   5971 N  N   . GLU B 1 364 ? 110.233 132.884 146.065 1.00 24.71  ? 364 GLU B N   1 
ATOM   5972 C  CA  . GLU B 1 364 ? 110.115 133.962 147.037 1.00 28.54  ? 364 GLU B CA  1 
ATOM   5973 C  C   . GLU B 1 364 ? 108.698 134.069 147.576 1.00 42.73  ? 364 GLU B C   1 
ATOM   5974 O  O   . GLU B 1 364 ? 108.499 134.512 148.710 1.00 45.89  ? 364 GLU B O   1 
ATOM   5975 C  CB  . GLU B 1 364 ? 110.542 135.284 146.410 1.00 31.88  ? 364 GLU B CB  1 
ATOM   5976 C  CG  . GLU B 1 364 ? 111.965 135.676 146.704 1.00 34.88  ? 364 GLU B CG  1 
ATOM   5977 C  CD  . GLU B 1 364 ? 112.436 136.826 145.843 1.00 48.78  ? 364 GLU B CD  1 
ATOM   5978 O  OE1 . GLU B 1 364 ? 111.747 137.151 144.856 1.00 49.53  ? 364 GLU B OE1 1 
ATOM   5979 O  OE2 . GLU B 1 364 ? 113.493 137.410 146.154 1.00 48.69  ? 364 GLU B OE2 1 
ATOM   5980 N  N   . ALA B 1 365 ? 107.702 133.684 146.777 1.00 38.46  ? 365 ALA B N   1 
ATOM   5981 C  CA  . ALA B 1 365 ? 106.330 133.671 147.267 1.00 29.01  ? 365 ALA B CA  1 
ATOM   5982 C  C   . ALA B 1 365 ? 106.107 132.525 148.242 1.00 33.27  ? 365 ALA B C   1 
ATOM   5983 O  O   . ALA B 1 365 ? 105.432 132.695 149.261 1.00 41.20  ? 365 ALA B O   1 
ATOM   5984 C  CB  . ALA B 1 365 ? 105.353 133.580 146.099 1.00 29.56  ? 365 ALA B CB  1 
ATOM   5985 N  N   . ILE B 1 366 ? 106.665 131.349 147.947 1.00 34.59  ? 366 ILE B N   1 
ATOM   5986 C  CA  . ILE B 1 366 ? 106.547 130.219 148.861 1.00 33.34  ? 366 ILE B CA  1 
ATOM   5987 C  C   . ILE B 1 366 ? 107.277 130.505 150.165 1.00 34.07  ? 366 ILE B C   1 
ATOM   5988 O  O   . ILE B 1 366 ? 106.840 130.073 151.236 1.00 40.99  ? 366 ILE B O   1 
ATOM   5989 C  CB  . ILE B 1 366 ? 107.068 128.935 148.193 1.00 32.05  ? 366 ILE B CB  1 
ATOM   5990 C  CG1 . ILE B 1 366 ? 106.425 128.750 146.823 1.00 30.30  ? 366 ILE B CG1 1 
ATOM   5991 C  CG2 . ILE B 1 366 ? 106.776 127.731 149.057 1.00 38.60  ? 366 ILE B CG2 1 
ATOM   5992 C  CD1 . ILE B 1 366 ? 107.031 127.635 146.025 1.00 36.14  ? 366 ILE B CD1 1 
ATOM   5993 N  N   . VAL B 1 367 ? 108.400 131.221 150.098 1.00 37.34  ? 367 VAL B N   1 
ATOM   5994 C  CA  . VAL B 1 367 ? 109.109 131.627 151.309 1.00 36.91  ? 367 VAL B CA  1 
ATOM   5995 C  C   . VAL B 1 367 ? 108.235 132.547 152.150 1.00 38.24  ? 367 VAL B C   1 
ATOM   5996 O  O   . VAL B 1 367 ? 108.187 132.431 153.379 1.00 44.17  ? 367 VAL B O   1 
ATOM   5997 C  CB  . VAL B 1 367 ? 110.448 132.291 150.939 1.00 31.44  ? 367 VAL B CB  1 
ATOM   5998 C  CG1 . VAL B 1 367 ? 110.887 133.247 152.020 1.00 34.34  ? 367 VAL B CG1 1 
ATOM   5999 C  CG2 . VAL B 1 367 ? 111.513 131.247 150.702 1.00 31.32  ? 367 VAL B CG2 1 
ATOM   6000 N  N   . CYS B 1 368 ? 107.524 133.470 151.501 1.00 43.01  ? 368 CYS B N   1 
ATOM   6001 C  CA  . CYS B 1 368 ? 106.665 134.399 152.228 1.00 43.09  ? 368 CYS B CA  1 
ATOM   6002 C  C   . CYS B 1 368 ? 105.428 133.713 152.796 1.00 42.34  ? 368 CYS B C   1 
ATOM   6003 O  O   . CYS B 1 368 ? 104.955 134.095 153.870 1.00 46.51  ? 368 CYS B O   1 
ATOM   6004 C  CB  . CYS B 1 368 ? 106.256 135.557 151.321 1.00 42.59  ? 368 CYS B CB  1 
ATOM   6005 S  SG  . CYS B 1 368 ? 107.610 136.639 150.841 1.00 50.72  ? 368 CYS B SG  1 
ATOM   6006 N  N   . ILE B 1 369 ? 104.877 132.724 152.092 1.00 39.35  ? 369 ILE B N   1 
ATOM   6007 C  CA  . ILE B 1 369 ? 103.718 132.009 152.619 1.00 37.97  ? 369 ILE B CA  1 
ATOM   6008 C  C   . ILE B 1 369 ? 104.117 131.133 153.799 1.00 45.51  ? 369 ILE B C   1 
ATOM   6009 O  O   . ILE B 1 369 ? 103.378 131.022 154.783 1.00 50.74  ? 369 ILE B O   1 
ATOM   6010 C  CB  . ILE B 1 369 ? 103.039 131.185 151.511 1.00 31.53  ? 369 ILE B CB  1 
ATOM   6011 C  CG1 . ILE B 1 369 ? 102.532 132.096 150.400 1.00 34.46  ? 369 ILE B CG1 1 
ATOM   6012 C  CG2 . ILE B 1 369 ? 101.879 130.406 152.076 1.00 38.84  ? 369 ILE B CG2 1 
ATOM   6013 C  CD1 . ILE B 1 369 ? 102.058 131.353 149.186 1.00 37.69  ? 369 ILE B CD1 1 
ATOM   6014 N  N   . LYS B 1 370 ? 105.284 130.493 153.721 1.00 42.91  ? 370 LYS B N   1 
ATOM   6015 C  CA  . LYS B 1 370 ? 105.699 129.576 154.778 1.00 40.60  ? 370 LYS B CA  1 
ATOM   6016 C  C   . LYS B 1 370 ? 106.008 130.320 156.072 1.00 38.68  ? 370 LYS B C   1 
ATOM   6017 O  O   . LYS B 1 370 ? 105.531 129.939 157.146 1.00 42.05  ? 370 LYS B O   1 
ATOM   6018 C  CB  . LYS B 1 370 ? 106.909 128.764 154.317 1.00 39.28  ? 370 LYS B CB  1 
ATOM   6019 C  CG  . LYS B 1 370 ? 107.467 127.825 155.367 1.00 37.85  ? 370 LYS B CG  1 
ATOM   6020 C  CD  . LYS B 1 370 ? 108.908 127.466 155.066 1.00 38.21  ? 370 LYS B CD  1 
ATOM   6021 C  CE  . LYS B 1 370 ? 109.507 126.602 156.159 1.00 37.74  ? 370 LYS B CE  1 
ATOM   6022 N  NZ  . LYS B 1 370 ? 108.980 125.217 156.140 1.00 36.17  ? 370 LYS B NZ  1 
ATOM   6023 N  N   . PHE B 1 371 ? 106.804 131.385 155.992 1.00 42.67  ? 371 PHE B N   1 
ATOM   6024 C  CA  . PHE B 1 371 ? 107.187 132.145 157.174 1.00 46.95  ? 371 PHE B CA  1 
ATOM   6025 C  C   . PHE B 1 371 ? 106.198 133.246 157.524 1.00 51.89  ? 371 PHE B C   1 
ATOM   6026 O  O   . PHE B 1 371 ? 106.323 133.851 158.593 1.00 53.74  ? 371 PHE B O   1 
ATOM   6027 C  CB  . PHE B 1 371 ? 108.577 132.761 156.984 1.00 44.59  ? 371 PHE B CB  1 
ATOM   6028 C  CG  . PHE B 1 371 ? 109.657 131.753 156.728 1.00 44.68  ? 371 PHE B CG  1 
ATOM   6029 C  CD1 . PHE B 1 371 ? 109.819 130.667 157.562 1.00 46.32  ? 371 PHE B CD1 1 
ATOM   6030 C  CD2 . PHE B 1 371 ? 110.510 131.892 155.652 1.00 43.11  ? 371 PHE B CD2 1 
ATOM   6031 C  CE1 . PHE B 1 371 ? 110.808 129.741 157.326 1.00 42.56  ? 371 PHE B CE1 1 
ATOM   6032 C  CE2 . PHE B 1 371 ? 111.499 130.965 155.415 1.00 45.74  ? 371 PHE B CE2 1 
ATOM   6033 C  CZ  . PHE B 1 371 ? 111.646 129.890 156.252 1.00 41.30  ? 371 PHE B CZ  1 
ATOM   6034 N  N   . GLY B 1 372 ? 105.227 133.522 156.660 1.00 55.02  ? 372 GLY B N   1 
ATOM   6035 C  CA  . GLY B 1 372 ? 104.250 134.557 156.925 1.00 56.09  ? 372 GLY B CA  1 
ATOM   6036 C  C   . GLY B 1 372 ? 102.930 133.985 157.388 1.00 59.68  ? 372 GLY B C   1 
ATOM   6037 O  O   . GLY B 1 372 ? 101.874 134.594 157.202 1.00 63.36  ? 372 GLY B O   1 
ATOM   6038 N  N   . GLN B 1 373 ? 102.983 132.796 157.986 1.00 65.51  ? 373 GLN B N   1 
ATOM   6039 C  CA  . GLN B 1 373 ? 101.784 132.137 158.481 1.00 66.20  ? 373 GLN B CA  1 
ATOM   6040 C  C   . GLN B 1 373 ? 101.180 132.842 159.687 1.00 70.25  ? 373 GLN B C   1 
ATOM   6041 O  O   . GLN B 1 373 ? 100.047 132.524 160.064 1.00 71.66  ? 373 GLN B O   1 
ATOM   6042 C  CB  . GLN B 1 373 ? 102.106 130.685 158.844 1.00 67.02  ? 373 GLN B CB  1 
ATOM   6043 C  CG  . GLN B 1 373 ? 102.242 129.743 157.657 1.00 63.62  ? 373 GLN B CG  1 
ATOM   6044 C  CD  . GLN B 1 373 ? 100.979 129.648 156.831 1.00 67.88  ? 373 GLN B CD  1 
ATOM   6045 O  OE1 . GLN B 1 373 ? 100.731 130.474 155.954 1.00 67.03  ? 373 GLN B OE1 1 
ATOM   6046 N  NE2 . GLN B 1 373 ? 100.170 128.633 157.105 1.00 70.49  ? 373 GLN B NE2 1 
ATOM   6047 N  N   . ASP B 1 374 ? 101.897 133.786 160.294 1.00 78.42  ? 374 ASP B N   1 
ATOM   6048 C  CA  . ASP B 1 374 ? 101.486 134.396 161.552 1.00 79.82  ? 374 ASP B CA  1 
ATOM   6049 C  C   . ASP B 1 374 ? 100.927 135.806 161.400 1.00 77.82  ? 374 ASP B C   1 
ATOM   6050 O  O   . ASP B 1 374 ? 100.000 136.173 162.127 1.00 80.55  ? 374 ASP B O   1 
ATOM   6051 C  CB  . ASP B 1 374 ? 102.665 134.421 162.529 1.00 77.91  ? 374 ASP B CB  1 
ATOM   6052 C  CG  . ASP B 1 374 ? 103.846 135.208 161.996 1.00 79.85  ? 374 ASP B CG  1 
ATOM   6053 O  OD1 . ASP B 1 374 ? 103.878 135.483 160.778 1.00 77.59  ? 374 ASP B OD1 1 
ATOM   6054 O  OD2 . ASP B 1 374 ? 104.745 135.547 162.794 1.00 79.16  ? 374 ASP B OD2 1 
ATOM   6055 N  N   . LEU B 1 375 ? 101.456 136.610 160.481 1.00 73.21  ? 375 LEU B N   1 
ATOM   6056 C  CA  . LEU B 1 375 ? 101.045 138.007 160.387 1.00 78.49  ? 375 LEU B CA  1 
ATOM   6057 C  C   . LEU B 1 375 ? 99.707  138.201 159.680 1.00 81.32  ? 375 LEU B C   1 
ATOM   6058 O  O   . LEU B 1 375 ? 99.344  139.345 159.383 1.00 79.89  ? 375 LEU B O   1 
ATOM   6059 C  CB  . LEU B 1 375 ? 102.130 138.840 159.698 1.00 82.01  ? 375 LEU B CB  1 
ATOM   6060 C  CG  . LEU B 1 375 ? 102.890 138.324 158.476 1.00 80.75  ? 375 LEU B CG  1 
ATOM   6061 C  CD1 . LEU B 1 375 ? 102.023 138.299 157.238 1.00 77.51  ? 375 LEU B CD1 1 
ATOM   6062 C  CD2 . LEU B 1 375 ? 104.104 139.201 158.248 1.00 77.84  ? 375 LEU B CD2 1 
ATOM   6063 N  N   . PHE B 1 376 ? 98.972  137.129 159.400 1.00 85.58  ? 376 PHE B N   1 
ATOM   6064 C  CA  . PHE B 1 376 ? 97.595  137.216 158.938 1.00 87.48  ? 376 PHE B CA  1 
ATOM   6065 C  C   . PHE B 1 376 ? 96.709  136.360 159.831 1.00 88.09  ? 376 PHE B C   1 
ATOM   6066 O  O   . PHE B 1 376 ? 97.075  135.237 160.190 1.00 86.77  ? 376 PHE B O   1 
ATOM   6067 C  CB  . PHE B 1 376 ? 97.447  136.761 157.483 1.00 86.75  ? 376 PHE B CB  1 
ATOM   6068 C  CG  . PHE B 1 376 ? 98.193  137.610 156.495 1.00 88.50  ? 376 PHE B CG  1 
ATOM   6069 C  CD1 . PHE B 1 376 ? 97.977  138.977 156.430 1.00 87.07  ? 376 PHE B CD1 1 
ATOM   6070 C  CD2 . PHE B 1 376 ? 99.081  137.035 155.601 1.00 89.91  ? 376 PHE B CD2 1 
ATOM   6071 C  CE1 . PHE B 1 376 ? 98.649  139.760 155.512 1.00 85.69  ? 376 PHE B CE1 1 
ATOM   6072 C  CE2 . PHE B 1 376 ? 99.756  137.813 154.677 1.00 90.33  ? 376 PHE B CE2 1 
ATOM   6073 C  CZ  . PHE B 1 376 ? 99.539  139.178 154.635 1.00 87.96  ? 376 PHE B CZ  1 
ATOM   6074 N  N   . SER B 1 377 ? 95.548  136.899 160.197 1.00 86.56  ? 377 SER B N   1 
ATOM   6075 C  CA  . SER B 1 377 ? 94.553  136.158 160.962 1.00 85.02  ? 377 SER B CA  1 
ATOM   6076 C  C   . SER B 1 377 ? 93.263  135.947 160.189 1.00 87.30  ? 377 SER B C   1 
ATOM   6077 O  O   . SER B 1 377 ? 92.839  134.802 159.995 1.00 85.47  ? 377 SER B O   1 
ATOM   6078 C  CB  . SER B 1 377 ? 94.262  136.888 162.282 1.00 84.16  ? 377 SER B CB  1 
ATOM   6079 O  OG  . SER B 1 377 ? 93.934  138.247 162.048 1.00 85.11  ? 377 SER B OG  1 
ATOM   6080 N  N   . LYS B 1 378 ? 92.627  137.028 159.732 1.00 90.55  ? 378 LYS B N   1 
ATOM   6081 C  CA  . LYS B 1 378 ? 91.417  136.951 158.924 1.00 88.50  ? 378 LYS B CA  1 
ATOM   6082 C  C   . LYS B 1 378 ? 91.574  137.713 157.615 1.00 88.59  ? 378 LYS B C   1 
ATOM   6083 O  O   . LYS B 1 378 ? 90.567  138.076 156.998 1.00 88.91  ? 378 LYS B O   1 
ATOM   6084 C  CB  . LYS B 1 378 ? 90.202  137.493 159.689 1.00 89.16  ? 378 LYS B CB  1 
ATOM   6085 C  CG  . LYS B 1 378 ? 89.792  136.681 160.912 1.00 90.36  ? 378 LYS B CG  1 
ATOM   6086 C  CD  . LYS B 1 378 ? 90.589  137.076 162.146 1.00 90.66  ? 378 LYS B CD  1 
ATOM   6087 C  CE  . LYS B 1 378 ? 90.576  135.971 163.185 1.00 89.88  ? 378 LYS B CE  1 
ATOM   6088 N  NZ  . LYS B 1 378 ? 91.496  136.265 164.319 1.00 89.72  ? 378 LYS B NZ  1 
ATOM   6089 N  N   . THR B 1 379 ? 92.808  137.967 157.188 1.00 85.54  ? 379 THR B N   1 
ATOM   6090 C  CA  . THR B 1 379 ? 93.058  138.788 156.014 1.00 86.80  ? 379 THR B CA  1 
ATOM   6091 C  C   . THR B 1 379 ? 92.596  138.079 154.746 1.00 88.24  ? 379 THR B C   1 
ATOM   6092 O  O   . THR B 1 379 ? 92.536  136.848 154.677 1.00 84.49  ? 379 THR B O   1 
ATOM   6093 C  CB  . THR B 1 379 ? 94.541  139.129 155.924 1.00 85.55  ? 379 THR B CB  1 
ATOM   6094 O  OG1 . THR B 1 379 ? 95.067  139.277 157.248 1.00 85.40  ? 379 THR B OG1 1 
ATOM   6095 C  CG2 . THR B 1 379 ? 94.748  140.429 155.161 1.00 87.89  ? 379 THR B CG2 1 
ATOM   6096 N  N   . GLN B 1 380 ? 92.279  138.878 153.731 1.00 81.02  ? 380 GLN B N   1 
ATOM   6097 C  CA  . GLN B 1 380 ? 91.574  138.414 152.547 1.00 75.53  ? 380 GLN B CA  1 
ATOM   6098 C  C   . GLN B 1 380 ? 92.532  138.227 151.378 1.00 78.74  ? 380 GLN B C   1 
ATOM   6099 O  O   . GLN B 1 380 ? 93.360  139.099 151.094 1.00 73.85  ? 380 GLN B O   1 
ATOM   6100 C  CB  . GLN B 1 380 ? 90.475  139.403 152.164 1.00 71.46  ? 380 GLN B CB  1 
ATOM   6101 C  CG  . GLN B 1 380 ? 89.341  139.472 153.164 1.00 78.74  ? 380 GLN B CG  1 
ATOM   6102 C  CD  . GLN B 1 380 ? 89.483  140.637 154.123 1.00 79.55  ? 380 GLN B CD  1 
ATOM   6103 O  OE1 . GLN B 1 380 ? 90.402  141.447 154.001 1.00 77.89  ? 380 GLN B OE1 1 
ATOM   6104 N  NE2 . GLN B 1 380 ? 88.570  140.729 155.084 1.00 75.47  ? 380 GLN B NE2 1 
ATOM   6105 N  N   . ILE B 1 381 ? 92.417  137.075 150.711 1.00 75.32  ? 381 ILE B N   1 
ATOM   6106 C  CA  . ILE B 1 381 ? 93.008  136.884 149.389 1.00 67.60  ? 381 ILE B CA  1 
ATOM   6107 C  C   . ILE B 1 381 ? 92.104  137.413 148.290 1.00 66.47  ? 381 ILE B C   1 
ATOM   6108 O  O   . ILE B 1 381 ? 92.499  137.416 147.119 1.00 66.35  ? 381 ILE B O   1 
ATOM   6109 C  CB  . ILE B 1 381 ? 93.311  135.393 149.150 1.00 66.81  ? 381 ILE B CB  1 
ATOM   6110 C  CG1 . ILE B 1 381 ? 94.430  135.224 148.119 1.00 71.69  ? 381 ILE B CG1 1 
ATOM   6111 C  CG2 . ILE B 1 381 ? 92.051  134.659 148.721 1.00 62.87  ? 381 ILE B CG2 1 
ATOM   6112 C  CD1 . ILE B 1 381 ? 94.809  133.786 147.847 1.00 68.79  ? 381 ILE B CD1 1 
ATOM   6113 N  N   . LEU B 1 382 ? 90.900  137.869 148.644 1.00 67.11  ? 382 LEU B N   1 
ATOM   6114 C  CA  . LEU B 1 382 ? 89.936  138.312 147.641 1.00 64.56  ? 382 LEU B CA  1 
ATOM   6115 C  C   . LEU B 1 382 ? 90.469  139.492 146.844 1.00 62.59  ? 382 LEU B C   1 
ATOM   6116 O  O   . LEU B 1 382 ? 90.203  139.609 145.643 1.00 62.20  ? 382 LEU B O   1 
ATOM   6117 C  CB  . LEU B 1 382 ? 88.608  138.676 148.306 1.00 62.84  ? 382 LEU B CB  1 
ATOM   6118 C  CG  . LEU B 1 382 ? 87.658  137.544 148.710 1.00 64.88  ? 382 LEU B CG  1 
ATOM   6119 C  CD1 . LEU B 1 382 ? 87.240  136.743 147.488 1.00 63.81  ? 382 LEU B CD1 1 
ATOM   6120 C  CD2 . LEU B 1 382 ? 88.248  136.635 149.781 1.00 66.38  ? 382 LEU B CD2 1 
ATOM   6121 N  N   . TYR B 1 383 ? 91.214  140.384 147.497 1.00 60.05  ? 383 TYR B N   1 
ATOM   6122 C  CA  . TYR B 1 383 ? 91.825  141.495 146.777 1.00 59.78  ? 383 TYR B CA  1 
ATOM   6123 C  C   . TYR B 1 383 ? 92.801  140.992 145.724 1.00 64.43  ? 383 TYR B C   1 
ATOM   6124 O  O   . TYR B 1 383 ? 92.845  141.516 144.605 1.00 67.75  ? 383 TYR B O   1 
ATOM   6125 C  CB  . TYR B 1 383 ? 92.529  142.428 147.753 1.00 57.97  ? 383 TYR B CB  1 
ATOM   6126 C  CG  . TYR B 1 383 ? 92.837  143.785 147.178 1.00 58.03  ? 383 TYR B CG  1 
ATOM   6127 C  CD1 . TYR B 1 383 ? 91.877  144.785 147.166 1.00 59.29  ? 383 TYR B CD1 1 
ATOM   6128 C  CD2 . TYR B 1 383 ? 94.083  144.067 146.645 1.00 54.62  ? 383 TYR B CD2 1 
ATOM   6129 C  CE1 . TYR B 1 383 ? 92.150  146.026 146.645 1.00 59.91  ? 383 TYR B CE1 1 
ATOM   6130 C  CE2 . TYR B 1 383 ? 94.363  145.304 146.123 1.00 57.42  ? 383 TYR B CE2 1 
ATOM   6131 C  CZ  . TYR B 1 383 ? 93.394  146.280 146.126 1.00 59.80  ? 383 TYR B CZ  1 
ATOM   6132 O  OH  . TYR B 1 383 ? 93.669  147.520 145.605 1.00 61.76  ? 383 TYR B OH  1 
ATOM   6133 N  N   . VAL B 1 384 ? 93.598  139.978 146.065 1.00 62.19  ? 384 VAL B N   1 
ATOM   6134 C  CA  . VAL B 1 384 ? 94.472  139.355 145.076 1.00 60.06  ? 384 VAL B CA  1 
ATOM   6135 C  C   . VAL B 1 384 ? 93.645  138.718 143.967 1.00 57.79  ? 384 VAL B C   1 
ATOM   6136 O  O   . VAL B 1 384 ? 93.971  138.840 142.782 1.00 57.03  ? 384 VAL B O   1 
ATOM   6137 C  CB  . VAL B 1 384 ? 95.406  138.339 145.757 1.00 57.80  ? 384 VAL B CB  1 
ATOM   6138 C  CG1 . VAL B 1 384 ? 95.930  137.344 144.751 1.00 62.25  ? 384 VAL B CG1 1 
ATOM   6139 C  CG2 . VAL B 1 384 ? 96.561  139.058 146.433 1.00 50.64  ? 384 VAL B CG2 1 
ATOM   6140 N  N   . VAL B 1 385 ? 92.555  138.039 144.330 1.00 64.02  ? 385 VAL B N   1 
ATOM   6141 C  CA  . VAL B 1 385 ? 91.641  137.511 143.321 1.00 65.13  ? 385 VAL B CA  1 
ATOM   6142 C  C   . VAL B 1 385 ? 91.021  138.649 142.520 1.00 64.28  ? 385 VAL B C   1 
ATOM   6143 O  O   . VAL B 1 385 ? 90.891  138.566 141.293 1.00 69.33  ? 385 VAL B O   1 
ATOM   6144 C  CB  . VAL B 1 385 ? 90.566  136.627 143.979 1.00 64.40  ? 385 VAL B CB  1 
ATOM   6145 C  CG1 . VAL B 1 385 ? 89.477  136.278 142.982 1.00 62.68  ? 385 VAL B CG1 1 
ATOM   6146 C  CG2 . VAL B 1 385 ? 91.190  135.364 144.536 1.00 63.21  ? 385 VAL B CG2 1 
ATOM   6147 N  N   . LEU B 1 386 ? 90.620  139.726 143.199 1.00 59.03  ? 386 LEU B N   1 
ATOM   6148 C  CA  . LEU B 1 386 ? 90.057  140.873 142.495 1.00 61.46  ? 386 LEU B CA  1 
ATOM   6149 C  C   . LEU B 1 386 ? 91.096  141.527 141.596 1.00 60.35  ? 386 LEU B C   1 
ATOM   6150 O  O   . LEU B 1 386 ? 90.781  141.951 140.479 1.00 64.47  ? 386 LEU B O   1 
ATOM   6151 C  CB  . LEU B 1 386 ? 89.495  141.881 143.497 1.00 64.27  ? 386 LEU B CB  1 
ATOM   6152 C  CG  . LEU B 1 386 ? 88.030  141.673 143.890 1.00 65.87  ? 386 LEU B CG  1 
ATOM   6153 C  CD1 . LEU B 1 386 ? 87.496  142.875 144.647 1.00 63.87  ? 386 LEU B CD1 1 
ATOM   6154 C  CD2 . LEU B 1 386 ? 87.175  141.381 142.667 1.00 64.57  ? 386 LEU B CD2 1 
ATOM   6155 N  N   . TRP B 1 387 ? 92.340  141.628 142.072 1.00 58.50  ? 387 TRP B N   1 
ATOM   6156 C  CA  . TRP B 1 387 ? 93.432  142.098 141.225 1.00 61.73  ? 387 TRP B CA  1 
ATOM   6157 C  C   . TRP B 1 387 ? 93.623  141.218 139.994 1.00 61.86  ? 387 TRP B C   1 
ATOM   6158 O  O   . TRP B 1 387 ? 93.995  141.720 138.928 1.00 60.06  ? 387 TRP B O   1 
ATOM   6159 C  CB  . TRP B 1 387 ? 94.721  142.186 142.047 1.00 60.32  ? 387 TRP B CB  1 
ATOM   6160 C  CG  . TRP B 1 387 ? 95.956  141.894 141.263 1.00 64.15  ? 387 TRP B CG  1 
ATOM   6161 C  CD1 . TRP B 1 387 ? 96.457  142.607 140.219 1.00 65.17  ? 387 TRP B CD1 1 
ATOM   6162 C  CD2 . TRP B 1 387 ? 96.864  140.803 141.477 1.00 67.07  ? 387 TRP B CD2 1 
ATOM   6163 N  NE1 . TRP B 1 387 ? 97.607  142.014 139.753 1.00 66.97  ? 387 TRP B NE1 1 
ATOM   6164 C  CE2 . TRP B 1 387 ? 97.881  140.910 140.516 1.00 66.76  ? 387 TRP B CE2 1 
ATOM   6165 C  CE3 . TRP B 1 387 ? 96.913  139.748 142.390 1.00 68.47  ? 387 TRP B CE3 1 
ATOM   6166 C  CZ2 . TRP B 1 387 ? 98.931  139.999 140.437 1.00 63.31  ? 387 TRP B CZ2 1 
ATOM   6167 C  CZ3 . TRP B 1 387 ? 97.961  138.843 142.309 1.00 63.10  ? 387 TRP B CZ3 1 
ATOM   6168 C  CH2 . TRP B 1 387 ? 98.952  138.976 141.343 1.00 60.09  ? 387 TRP B CH2 1 
ATOM   6169 N  N   . LEU B 1 388 ? 93.366  139.915 140.112 1.00 61.32  ? 388 LEU B N   1 
ATOM   6170 C  CA  . LEU B 1 388 ? 93.492  139.031 138.958 1.00 58.75  ? 388 LEU B CA  1 
ATOM   6171 C  C   . LEU B 1 388 ? 92.523  139.418 137.849 1.00 59.25  ? 388 LEU B C   1 
ATOM   6172 O  O   . LEU B 1 388 ? 92.885  139.404 136.668 1.00 61.84  ? 388 LEU B O   1 
ATOM   6173 C  CB  . LEU B 1 388 ? 93.260  137.582 139.379 1.00 62.68  ? 388 LEU B CB  1 
ATOM   6174 C  CG  . LEU B 1 388 ? 94.493  136.699 139.550 1.00 66.59  ? 388 LEU B CG  1 
ATOM   6175 C  CD1 . LEU B 1 388 ? 95.121  136.421 138.214 1.00 61.19  ? 388 LEU B CD1 1 
ATOM   6176 C  CD2 . LEU B 1 388 ? 95.498  137.336 140.465 1.00 64.78  ? 388 LEU B CD2 1 
ATOM   6177 N  N   . LEU B 1 389 ? 91.279  139.747 138.205 1.00 63.47  ? 389 LEU B N   1 
ATOM   6178 C  CA  . LEU B 1 389 ? 90.297  140.124 137.193 1.00 63.34  ? 389 LEU B CA  1 
ATOM   6179 C  C   . LEU B 1 389 ? 90.603  141.493 136.600 1.00 64.83  ? 389 LEU B C   1 
ATOM   6180 O  O   . LEU B 1 389 ? 90.522  141.678 135.381 1.00 68.89  ? 389 LEU B O   1 
ATOM   6181 C  CB  . LEU B 1 389 ? 88.890  140.104 137.788 1.00 62.21  ? 389 LEU B CB  1 
ATOM   6182 C  CG  . LEU B 1 389 ? 87.771  140.461 136.809 1.00 64.21  ? 389 LEU B CG  1 
ATOM   6183 C  CD1 . LEU B 1 389 ? 87.462  139.286 135.898 1.00 59.26  ? 389 LEU B CD1 1 
ATOM   6184 C  CD2 . LEU B 1 389 ? 86.524  140.917 137.545 1.00 65.41  ? 389 LEU B CD2 1 
ATOM   6185 N  N   . CYS B 1 390 ? 90.964  142.463 137.441 1.00 66.57  ? 390 CYS B N   1 
ATOM   6186 C  CA  . CYS B 1 390 ? 91.251  143.809 136.963 1.00 64.32  ? 390 CYS B CA  1 
ATOM   6187 C  C   . CYS B 1 390 ? 92.502  143.879 136.101 1.00 70.41  ? 390 CYS B C   1 
ATOM   6188 O  O   . CYS B 1 390 ? 92.730  144.912 135.463 1.00 78.79  ? 390 CYS B O   1 
ATOM   6189 C  CB  . CYS B 1 390 ? 91.385  144.769 138.141 1.00 69.27  ? 390 CYS B CB  1 
ATOM   6190 S  SG  . CYS B 1 390 ? 89.961  144.768 139.245 1.00 87.03  ? 390 CYS B SG  1 
ATOM   6191 N  N   . VAL B 1 391 ? 93.320  142.828 136.075 1.00 64.18  ? 391 VAL B N   1 
ATOM   6192 C  CA  . VAL B 1 391 ? 94.432  142.779 135.131 1.00 64.03  ? 391 VAL B CA  1 
ATOM   6193 C  C   . VAL B 1 391 ? 93.954  142.279 133.773 1.00 63.16  ? 391 VAL B C   1 
ATOM   6194 O  O   . VAL B 1 391 ? 94.309  142.837 132.730 1.00 61.96  ? 391 VAL B O   1 
ATOM   6195 C  CB  . VAL B 1 391 ? 95.574  141.909 135.691 1.00 62.46  ? 391 VAL B CB  1 
ATOM   6196 C  CG1 . VAL B 1 391 ? 96.441  141.381 134.572 1.00 59.27  ? 391 VAL B CG1 1 
ATOM   6197 C  CG2 . VAL B 1 391 ? 96.415  142.707 136.661 1.00 59.26  ? 391 VAL B CG2 1 
ATOM   6198 N  N   . ALA B 1 392 ? 93.133  141.226 133.765 1.00 62.62  ? 392 ALA B N   1 
ATOM   6199 C  CA  . ALA B 1 392 ? 92.556  140.751 132.512 1.00 62.18  ? 392 ALA B CA  1 
ATOM   6200 C  C   . ALA B 1 392 ? 91.624  141.792 131.909 1.00 67.98  ? 392 ALA B C   1 
ATOM   6201 O  O   . ALA B 1 392 ? 91.575  141.959 130.685 1.00 72.67  ? 392 ALA B O   1 
ATOM   6202 C  CB  . ALA B 1 392 ? 91.813  139.436 132.734 1.00 60.55  ? 392 ALA B CB  1 
ATOM   6203 N  N   . PHE B 1 393 ? 90.869  142.496 132.755 1.00 72.71  ? 393 PHE B N   1 
ATOM   6204 C  CA  . PHE B 1 393 ? 90.030  143.590 132.276 1.00 71.39  ? 393 PHE B CA  1 
ATOM   6205 C  C   . PHE B 1 393 ? 90.860  144.644 131.553 1.00 70.69  ? 393 PHE B C   1 
ATOM   6206 O  O   . PHE B 1 393 ? 90.370  145.306 130.633 1.00 73.13  ? 393 PHE B O   1 
ATOM   6207 C  CB  . PHE B 1 393 ? 89.271  144.208 133.452 1.00 75.69  ? 393 PHE B CB  1 
ATOM   6208 C  CG  . PHE B 1 393 ? 88.500  145.452 133.103 1.00 79.95  ? 393 PHE B CG  1 
ATOM   6209 C  CD1 . PHE B 1 393 ? 87.706  145.506 131.968 1.00 77.57  ? 393 PHE B CD1 1 
ATOM   6210 C  CD2 . PHE B 1 393 ? 88.580  146.574 133.910 1.00 79.23  ? 393 PHE B CD2 1 
ATOM   6211 C  CE1 . PHE B 1 393 ? 87.005  146.656 131.649 1.00 74.64  ? 393 PHE B CE1 1 
ATOM   6212 C  CE2 . PHE B 1 393 ? 87.882  147.724 133.597 1.00 77.02  ? 393 PHE B CE2 1 
ATOM   6213 C  CZ  . PHE B 1 393 ? 87.094  147.764 132.465 1.00 75.51  ? 393 PHE B CZ  1 
ATOM   6214 N  N   . THR B 1 394 ? 92.122  144.806 131.942 1.00 69.44  ? 394 THR B N   1 
ATOM   6215 C  CA  . THR B 1 394 ? 92.970  145.817 131.326 1.00 70.02  ? 394 THR B CA  1 
ATOM   6216 C  C   . THR B 1 394 ? 93.800  145.278 130.165 1.00 69.35  ? 394 THR B C   1 
ATOM   6217 O  O   . THR B 1 394 ? 94.254  146.068 129.331 1.00 70.30  ? 394 THR B O   1 
ATOM   6218 C  CB  . THR B 1 394 ? 93.892  146.442 132.375 1.00 69.36  ? 394 THR B CB  1 
ATOM   6219 O  OG1 . THR B 1 394 ? 93.164  146.631 133.593 1.00 70.16  ? 394 THR B OG1 1 
ATOM   6220 C  CG2 . THR B 1 394 ? 94.371  147.799 131.900 1.00 71.18  ? 394 THR B CG2 1 
ATOM   6221 N  N   . THR B 1 395 ? 94.019  143.964 130.085 1.00 70.08  ? 395 THR B N   1 
ATOM   6222 C  CA  . THR B 1 395 ? 94.594  143.403 128.866 1.00 71.27  ? 395 THR B CA  1 
ATOM   6223 C  C   . THR B 1 395 ? 93.560  143.368 127.749 1.00 73.26  ? 395 THR B C   1 
ATOM   6224 O  O   . THR B 1 395 ? 93.862  143.721 126.604 1.00 76.77  ? 395 THR B O   1 
ATOM   6225 C  CB  . THR B 1 395 ? 95.152  142.001 129.122 1.00 70.02  ? 395 THR B CB  1 
ATOM   6226 O  OG1 . THR B 1 395 ? 96.344  142.098 129.903 1.00 70.22  ? 395 THR B OG1 1 
ATOM   6227 C  CG2 . THR B 1 395 ? 95.495  141.311 127.818 1.00 65.97  ? 395 THR B CG2 1 
ATOM   6228 N  N   . PHE B 1 396 ? 92.331  142.962 128.068 1.00 78.01  ? 396 PHE B N   1 
ATOM   6229 C  CA  . PHE B 1 396 ? 91.276  142.953 127.063 1.00 77.68  ? 396 PHE B CA  1 
ATOM   6230 C  C   . PHE B 1 396 ? 90.978  144.362 126.567 1.00 80.93  ? 396 PHE B C   1 
ATOM   6231 O  O   . PHE B 1 396 ? 90.734  144.567 125.373 1.00 84.90  ? 396 PHE B O   1 
ATOM   6232 C  CB  . PHE B 1 396 ? 90.016  142.300 127.626 1.00 76.96  ? 396 PHE B CB  1 
ATOM   6233 C  CG  . PHE B 1 396 ? 88.790  142.544 126.798 1.00 82.38  ? 396 PHE B CG  1 
ATOM   6234 C  CD1 . PHE B 1 396 ? 88.692  142.031 125.517 1.00 83.65  ? 396 PHE B CD1 1 
ATOM   6235 C  CD2 . PHE B 1 396 ? 87.738  143.289 127.298 1.00 82.74  ? 396 PHE B CD2 1 
ATOM   6236 C  CE1 . PHE B 1 396 ? 87.565  142.256 124.750 1.00 83.02  ? 396 PHE B CE1 1 
ATOM   6237 C  CE2 . PHE B 1 396 ? 86.609  143.517 126.537 1.00 82.13  ? 396 PHE B CE2 1 
ATOM   6238 C  CZ  . PHE B 1 396 ? 86.522  143.000 125.262 1.00 81.77  ? 396 PHE B CZ  1 
ATOM   6239 N  N   . LEU B 1 397 ? 90.985  145.346 127.467 1.00 78.39  ? 397 LEU B N   1 
ATOM   6240 C  CA  . LEU B 1 397 ? 90.816  146.727 127.033 1.00 76.84  ? 397 LEU B CA  1 
ATOM   6241 C  C   . LEU B 1 397 ? 92.029  147.222 126.257 1.00 76.85  ? 397 LEU B C   1 
ATOM   6242 O  O   . LEU B 1 397 ? 91.895  148.107 125.406 1.00 81.67  ? 397 LEU B O   1 
ATOM   6243 C  CB  . LEU B 1 397 ? 90.551  147.638 128.232 1.00 83.85  ? 397 LEU B CB  1 
ATOM   6244 C  CG  . LEU B 1 397 ? 89.122  147.734 128.784 1.00 87.47  ? 397 LEU B CG  1 
ATOM   6245 C  CD1 . LEU B 1 397 ? 88.986  148.949 129.695 1.00 81.77  ? 397 LEU B CD1 1 
ATOM   6246 C  CD2 . LEU B 1 397 ? 88.082  147.779 127.671 1.00 85.21  ? 397 LEU B CD2 1 
ATOM   6247 N  N   . CYS B 1 398 ? 93.216  146.683 126.542 1.00 80.74  ? 398 CYS B N   1 
ATOM   6248 C  CA  . CYS B 1 398 ? 94.401  147.067 125.781 1.00 83.20  ? 398 CYS B CA  1 
ATOM   6249 C  C   . CYS B 1 398 ? 94.325  146.560 124.347 1.00 82.99  ? 398 CYS B C   1 
ATOM   6250 O  O   . CYS B 1 398 ? 94.699  147.273 123.410 1.00 85.37  ? 398 CYS B O   1 
ATOM   6251 C  CB  . CYS B 1 398 ? 95.664  146.541 126.463 1.00 86.06  ? 398 CYS B CB  1 
ATOM   6252 S  SG  . CYS B 1 398 ? 96.464  147.700 127.598 1.00 88.60  ? 398 CYS B SG  1 
ATOM   6253 N  N   . LEU B 1 399 ? 93.858  145.325 124.158 1.00 86.26  ? 399 LEU B N   1 
ATOM   6254 C  CA  . LEU B 1 399 ? 93.722  144.785 122.810 1.00 86.98  ? 399 LEU B CA  1 
ATOM   6255 C  C   . LEU B 1 399 ? 92.656  145.528 122.020 1.00 88.19  ? 399 LEU B C   1 
ATOM   6256 O  O   . LEU B 1 399 ? 92.845  145.818 120.834 1.00 90.95  ? 399 LEU B O   1 
ATOM   6257 C  CB  . LEU B 1 399 ? 93.400  143.296 122.874 1.00 87.13  ? 399 LEU B CB  1 
ATOM   6258 C  CG  . LEU B 1 399 ? 94.569  142.403 123.276 1.00 86.41  ? 399 LEU B CG  1 
ATOM   6259 C  CD1 . LEU B 1 399 ? 94.133  141.406 124.329 1.00 86.23  ? 399 LEU B CD1 1 
ATOM   6260 C  CD2 . LEU B 1 399 ? 95.115  141.695 122.056 1.00 89.79  ? 399 LEU B CD2 1 
ATOM   6261 N  N   . TYR B 1 400 ? 91.526  145.839 122.655 1.00 97.81  ? 400 TYR B N   1 
ATOM   6262 C  CA  . TYR B 1 400 ? 90.482  146.595 121.973 1.00 99.23  ? 400 TYR B CA  1 
ATOM   6263 C  C   . TYR B 1 400 ? 90.979  147.979 121.577 1.00 98.72  ? 400 TYR B C   1 
ATOM   6264 O  O   . TYR B 1 400 ? 90.712  148.449 120.467 1.00 101.82 ? 400 TYR B O   1 
ATOM   6265 C  CB  . TYR B 1 400 ? 89.246  146.701 122.864 1.00 100.89 ? 400 TYR B CB  1 
ATOM   6266 C  CG  . TYR B 1 400 ? 88.461  147.978 122.675 1.00 101.94 ? 400 TYR B CG  1 
ATOM   6267 C  CD1 . TYR B 1 400 ? 87.560  148.112 121.628 1.00 100.03 ? 400 TYR B CD1 1 
ATOM   6268 C  CD2 . TYR B 1 400 ? 88.620  149.050 123.543 1.00 101.68 ? 400 TYR B CD2 1 
ATOM   6269 C  CE1 . TYR B 1 400 ? 86.841  149.276 121.451 1.00 100.59 ? 400 TYR B CE1 1 
ATOM   6270 C  CE2 . TYR B 1 400 ? 87.907  150.218 123.373 1.00 101.15 ? 400 TYR B CE2 1 
ATOM   6271 C  CZ  . TYR B 1 400 ? 87.019  150.326 122.326 1.00 101.55 ? 400 TYR B CZ  1 
ATOM   6272 O  OH  . TYR B 1 400 ? 86.305  151.489 122.155 1.00 102.50 ? 400 TYR B OH  1 
ATOM   6273 N  N   . GLY B 1 401 ? 91.715  148.642 122.470 1.00 100.73 ? 401 GLY B N   1 
ATOM   6274 C  CA  . GLY B 1 401 ? 92.224  149.970 122.180 1.00 101.09 ? 401 GLY B CA  1 
ATOM   6275 C  C   . GLY B 1 401 ? 93.300  149.999 121.118 1.00 102.69 ? 401 GLY B C   1 
ATOM   6276 O  O   . GLY B 1 401 ? 93.651  151.082 120.638 1.00 104.38 ? 401 GLY B O   1 
ATOM   6277 N  N   . MET B 1 402 ? 93.841  148.840 120.749 1.00 106.01 ? 402 MET B N   1 
ATOM   6278 C  CA  . MET B 1 402 ? 94.817  148.755 119.670 1.00 106.59 ? 402 MET B CA  1 
ATOM   6279 C  C   . MET B 1 402 ? 94.261  148.098 118.416 1.00 107.00 ? 402 MET B C   1 
ATOM   6280 O  O   . MET B 1 402 ? 94.716  148.417 117.313 1.00 108.22 ? 402 MET B O   1 
ATOM   6281 C  CB  . MET B 1 402 ? 96.081  148.025 120.159 1.00 107.00 ? 402 MET B CB  1 
ATOM   6282 C  CG  . MET B 1 402 ? 95.993  146.514 120.417 1.00 109.70 ? 402 MET B CG  1 
ATOM   6283 S  SD  . MET B 1 402 ? 95.699  145.405 119.024 1.00 113.63 ? 402 MET B SD  1 
ATOM   6284 C  CE  . MET B 1 402 ? 97.235  145.596 118.127 1.00 107.21 ? 402 MET B CE  1 
ATOM   6285 N  N   . ILE B 1 403 ? 93.294  147.189 118.557 1.00 112.25 ? 403 ILE B N   1 
ATOM   6286 C  CA  . ILE B 1 403 ? 92.570  146.688 117.393 1.00 114.02 ? 403 ILE B CA  1 
ATOM   6287 C  C   . ILE B 1 403 ? 91.776  147.816 116.745 1.00 115.61 ? 403 ILE B C   1 
ATOM   6288 O  O   . ILE B 1 403 ? 91.785  147.983 115.520 1.00 116.70 ? 403 ILE B O   1 
ATOM   6289 C  CB  . ILE B 1 403 ? 91.661  145.512 117.792 1.00 114.90 ? 403 ILE B CB  1 
ATOM   6290 C  CG1 . ILE B 1 403 ? 92.466  144.212 117.849 1.00 114.86 ? 403 ILE B CG1 1 
ATOM   6291 C  CG2 . ILE B 1 403 ? 90.487  145.384 116.831 1.00 114.56 ? 403 ILE B CG2 1 
ATOM   6292 C  CD1 . ILE B 1 403 ? 91.631  142.984 118.142 1.00 113.92 ? 403 ILE B CD1 1 
ATOM   6293 N  N   . TRP B 1 404 ? 91.081  148.610 117.561 1.00 126.46 ? 404 TRP B N   1 
ATOM   6294 C  CA  . TRP B 1 404 ? 90.390  149.791 117.060 1.00 127.07 ? 404 TRP B CA  1 
ATOM   6295 C  C   . TRP B 1 404 ? 91.361  150.863 116.582 1.00 126.85 ? 404 TRP B C   1 
ATOM   6296 O  O   . TRP B 1 404 ? 90.979  151.704 115.761 1.00 127.07 ? 404 TRP B O   1 
ATOM   6297 C  CB  . TRP B 1 404 ? 89.468  150.348 118.149 1.00 127.29 ? 404 TRP B CB  1 
ATOM   6298 C  CG  . TRP B 1 404 ? 89.085  151.790 117.980 1.00 129.21 ? 404 TRP B CG  1 
ATOM   6299 C  CD1 . TRP B 1 404 ? 87.932  152.272 117.434 1.00 128.83 ? 404 TRP B CD1 1 
ATOM   6300 C  CD2 . TRP B 1 404 ? 89.853  152.936 118.374 1.00 129.61 ? 404 TRP B CD2 1 
ATOM   6301 N  NE1 . TRP B 1 404 ? 87.936  153.646 117.457 1.00 130.26 ? 404 TRP B NE1 1 
ATOM   6302 C  CE2 . TRP B 1 404 ? 89.105  154.078 118.027 1.00 130.82 ? 404 TRP B CE2 1 
ATOM   6303 C  CE3 . TRP B 1 404 ? 91.102  153.106 118.977 1.00 126.59 ? 404 TRP B CE3 1 
ATOM   6304 C  CZ2 . TRP B 1 404 ? 89.564  155.372 118.266 1.00 129.02 ? 404 TRP B CZ2 1 
ATOM   6305 C  CZ3 . TRP B 1 404 ? 91.556  154.389 119.213 1.00 127.26 ? 404 TRP B CZ3 1 
ATOM   6306 C  CH2 . TRP B 1 404 ? 90.789  155.506 118.859 1.00 127.80 ? 404 TRP B CH2 1 
ATOM   6307 N  N   . TYR B 1 405 ? 92.604  150.848 117.071 1.00 126.66 ? 405 TYR B N   1 
ATOM   6308 C  CA  . TYR B 1 405 ? 93.571  151.871 116.684 1.00 126.92 ? 405 TYR B CA  1 
ATOM   6309 C  C   . TYR B 1 405 ? 93.855  151.827 115.189 1.00 128.34 ? 405 TYR B C   1 
ATOM   6310 O  O   . TYR B 1 405 ? 94.018  152.874 114.550 1.00 127.63 ? 405 TYR B O   1 
ATOM   6311 C  CB  . TYR B 1 405 ? 94.866  151.696 117.478 1.00 127.49 ? 405 TYR B CB  1 
ATOM   6312 C  CG  . TYR B 1 405 ? 96.057  152.404 116.873 1.00 129.80 ? 405 TYR B CG  1 
ATOM   6313 C  CD1 . TYR B 1 405 ? 96.167  153.787 116.920 1.00 129.94 ? 405 TYR B CD1 1 
ATOM   6314 C  CD2 . TYR B 1 405 ? 97.069  151.689 116.246 1.00 129.00 ? 405 TYR B CD2 1 
ATOM   6315 C  CE1 . TYR B 1 405 ? 97.256  154.438 116.365 1.00 128.35 ? 405 TYR B CE1 1 
ATOM   6316 C  CE2 . TYR B 1 405 ? 98.159  152.330 115.688 1.00 128.00 ? 405 TYR B CE2 1 
ATOM   6317 C  CZ  . TYR B 1 405 ? 98.248  153.703 115.751 1.00 128.20 ? 405 TYR B CZ  1 
ATOM   6318 O  OH  . TYR B 1 405 ? 99.332  154.343 115.197 1.00 127.52 ? 405 TYR B OH  1 
ATOM   6319 N  N   . ALA B 1 406 ? 93.930  150.624 114.615 1.00 131.57 ? 406 ALA B N   1 
ATOM   6320 C  CA  . ALA B 1 406 ? 94.146  150.504 113.177 1.00 131.85 ? 406 ALA B CA  1 
ATOM   6321 C  C   . ALA B 1 406 ? 92.992  151.116 112.395 1.00 131.42 ? 406 ALA B C   1 
ATOM   6322 O  O   . ALA B 1 406 ? 93.207  151.775 111.370 1.00 130.36 ? 406 ALA B O   1 
ATOM   6323 C  CB  . ALA B 1 406 ? 94.337  149.037 112.794 1.00 131.75 ? 406 ALA B CB  1 
ATOM   6324 N  N   . GLU B 1 407 ? 91.759  150.905 112.861 1.00 136.61 ? 407 GLU B N   1 
ATOM   6325 C  CA  . GLU B 1 407 ? 90.598  151.468 112.178 1.00 136.50 ? 407 GLU B CA  1 
ATOM   6326 C  C   . GLU B 1 407 ? 90.626  152.991 112.198 1.00 137.27 ? 407 GLU B C   1 
ATOM   6327 O  O   . GLU B 1 407 ? 90.317  153.638 111.190 1.00 137.63 ? 407 GLU B O   1 
ATOM   6328 C  CB  . GLU B 1 407 ? 89.313  150.941 112.816 1.00 136.52 ? 407 GLU B CB  1 
ATOM   6329 C  CG  . GLU B 1 407 ? 89.241  149.422 112.886 1.00 137.48 ? 407 GLU B CG  1 
ATOM   6330 C  CD  . GLU B 1 407 ? 88.103  148.929 113.755 1.00 137.00 ? 407 GLU B CD  1 
ATOM   6331 O  OE1 . GLU B 1 407 ? 87.331  149.770 114.262 1.00 137.23 ? 407 GLU B OE1 1 
ATOM   6332 O  OE2 . GLU B 1 407 ? 87.981  147.700 113.933 1.00 136.14 ? 407 GLU B OE2 1 
ATOM   6333 N  N   . HIS B 1 408 ? 90.992  153.581 113.330 1.00 140.57 ? 408 HIS B N   1 
ATOM   6334 C  CA  . HIS B 1 408 ? 91.100  155.033 113.433 1.00 141.08 ? 408 HIS B CA  1 
ATOM   6335 C  C   . HIS B 1 408 ? 92.554  155.463 113.601 1.00 139.87 ? 408 HIS B C   1 
ATOM   6336 O  O   . HIS B 1 408 ? 93.419  155.085 112.811 1.00 139.50 ? 408 HIS B O   1 
ATOM   6337 C  CB  . HIS B 1 408 ? 90.257  155.556 114.597 1.00 139.48 ? 408 HIS B CB  1 
ATOM   6338 C  CG  . HIS B 1 408 ? 88.794  155.639 114.294 1.00 139.81 ? 408 HIS B CG  1 
ATOM   6339 N  ND1 . HIS B 1 408 ? 88.043  154.539 113.940 1.00 139.77 ? 408 HIS B ND1 1 
ATOM   6340 C  CD2 . HIS B 1 408 ? 87.942  156.691 114.291 1.00 139.41 ? 408 HIS B CD2 1 
ATOM   6341 C  CE1 . HIS B 1 408 ? 86.792  154.909 113.733 1.00 139.94 ? 408 HIS B CE1 1 
ATOM   6342 N  NE2 . HIS B 1 408 ? 86.704  156.211 113.940 1.00 139.66 ? 408 HIS B NE2 1 
HETATM 6343 O  O2  . PSF C 2 .   ? 130.866 107.609 125.161 1.00 40.27  ? 501 PSF A O2  1 
HETATM 6344 O  O1  . PSF C 2 .   ? 131.344 109.311 123.411 1.00 40.85  ? 501 PSF A O1  1 
HETATM 6345 P  P   . PSF C 2 .   ? 130.090 108.472 124.015 1.00 44.36  ? 501 PSF A P   1 
HETATM 6346 O  O4  . PSF C 2 .   ? 129.639 107.485 122.997 1.00 38.47  ? 501 PSF A O4  1 
HETATM 6347 O  O3  . PSF C 2 .   ? 129.116 109.398 124.662 1.00 54.37  ? 501 PSF A O3  1 
HETATM 6348 C  C2  . PSF C 2 .   ? 130.142 107.074 126.241 1.00 36.37  ? 501 PSF A C2  1 
HETATM 6349 C  C3  . PSF C 2 .   ? 130.991 107.154 127.493 1.00 35.23  ? 501 PSF A C3  1 
HETATM 6350 O  O11 . PSF C 2 .   ? 132.125 106.293 127.398 1.00 44.42  ? 501 PSF A O11 1 
HETATM 6351 O  O12 . PSF C 2 .   ? 133.394 107.078 129.059 1.00 40.72  ? 501 PSF A O12 1 
HETATM 6352 C  C1  . PSF C 2 .   ? 132.945 106.153 128.437 1.00 43.66  ? 501 PSF A C1  1 
HETATM 6353 C  C4  . PSF C 2 .   ? 130.214 106.697 128.699 1.00 38.55  ? 501 PSF A C4  1 
HETATM 6354 C  C5  . PSF C 2 .   ? 128.987 104.733 128.949 1.00 39.73  ? 501 PSF A C5  1 
HETATM 6355 O  O51 . PSF C 2 .   ? 129.546 103.710 128.661 1.00 46.81  ? 501 PSF A O51 1 
HETATM 6356 O  O52 . PSF C 2 .   ? 129.150 105.857 128.267 1.00 40.62  ? 501 PSF A O52 1 
HETATM 6357 C  C6  . PSF C 2 .   ? 128.066 104.913 130.118 1.00 39.60  ? 501 PSF A C6  1 
HETATM 6358 C  C7  . PSF C 2 .   ? 128.587 104.259 131.385 1.00 44.41  ? 501 PSF A C7  1 
HETATM 6359 C  C13 . PSF C 2 .   ? 133.229 104.701 128.710 1.00 44.37  ? 501 PSF A C13 1 
HETATM 6360 C  C14 . PSF C 2 .   ? 134.010 104.489 130.012 1.00 43.30  ? 501 PSF A C14 1 
HETATM 6361 C  C15 . PSF C 2 .   ? 133.140 104.366 131.258 1.00 39.34  ? 501 PSF A C15 1 
HETATM 6362 N  N   . PSF C 2 .   ? 133.954 109.576 120.994 1.00 37.36  ? 501 PSF A N   1 
HETATM 6363 C  CA  . PSF C 2 .   ? 133.538 109.361 122.380 1.00 37.78  ? 501 PSF A CA  1 
HETATM 6364 C  CB  . PSF C 2 .   ? 132.140 108.772 122.380 1.00 37.84  ? 501 PSF A CB  1 
HETATM 6365 C  C   . PSF C 2 .   ? 134.503 108.451 123.155 1.00 45.78  ? 501 PSF A C   1 
HETATM 6366 O  OT1 . PSF C 2 .   ? 135.715 108.664 122.952 1.00 50.36  ? 501 PSF A OT1 1 
HETATM 6367 O  OT2 . PSF C 2 .   ? 134.015 107.591 123.909 1.00 45.94  ? 501 PSF A OT2 1 
HETATM 6368 C  C8  . PSF C 2 .   ? 127.461 103.777 132.288 1.00 46.86  ? 501 PSF A C8  1 
HETATM 6369 C  C9  . PSF C 2 .   ? 126.654 104.920 132.887 1.00 45.14  ? 501 PSF A C9  1 
HETATM 6370 C  C10 . PSF C 2 .   ? 125.453 104.445 133.691 1.00 39.54  ? 501 PSF A C10 1 
HETATM 6371 C  C16 . PSF C 2 .   ? 132.941 105.691 131.982 1.00 44.51  ? 501 PSF A C16 1 
HETATM 6372 C  C17 . PSF C 2 .   ? 132.229 105.540 133.318 1.00 38.92  ? 501 PSF A C17 1 
HETATM 6373 O  O2  . PSF D 2 .   ? 118.013 106.555 120.788 1.00 45.78  ? 502 PSF A O2  1 
HETATM 6374 O  O1  . PSF D 2 .   ? 119.318 107.973 119.215 1.00 50.30  ? 502 PSF A O1  1 
HETATM 6375 P  P   . PSF D 2 .   ? 117.966 107.063 119.241 1.00 54.67  ? 502 PSF A P   1 
HETATM 6376 O  O4  . PSF D 2 .   ? 118.160 105.832 118.420 1.00 55.60  ? 502 PSF A O4  1 
HETATM 6377 O  O3  . PSF D 2 .   ? 116.773 107.942 119.038 1.00 54.62  ? 502 PSF A O3  1 
HETATM 6378 C  C2  . PSF D 2 .   ? 117.554 107.409 121.805 1.00 42.84  ? 502 PSF A C2  1 
HETATM 6379 C  C3  . PSF D 2 .   ? 117.251 106.555 123.016 1.00 45.33  ? 502 PSF A C3  1 
HETATM 6380 O  O11 . PSF D 2 .   ? 118.345 106.610 123.925 1.00 49.73  ? 502 PSF A O11 1 
HETATM 6381 O  O12 . PSF D 2 .   ? 118.160 108.625 124.859 1.00 55.04  ? 502 PSF A O12 1 
HETATM 6382 C  C1  . PSF D 2 .   ? 118.312 107.438 124.961 1.00 50.54  ? 502 PSF A C1  1 
HETATM 6383 C  C4  . PSF D 2 .   ? 117.104 105.107 122.624 1.00 45.05  ? 502 PSF A C4  1 
HETATM 6384 C  C5  . PSF D 2 .   ? 116.083 103.481 123.944 1.00 50.50  ? 502 PSF A C5  1 
HETATM 6385 O  O51 . PSF D 2 .   ? 115.491 103.053 122.990 1.00 51.38  ? 502 PSF A O51 1 
HETATM 6386 O  O52 . PSF D 2 .   ? 117.070 104.353 123.830 1.00 49.27  ? 502 PSF A O52 1 
HETATM 6387 C  C6  . PSF D 2 .   ? 115.816 103.130 125.378 1.00 47.35  ? 502 PSF A C6  1 
HETATM 6388 C  C7  . PSF D 2 .   ? 117.079 102.968 126.201 1.00 50.19  ? 502 PSF A C7  1 
HETATM 6389 C  C13 . PSF D 2 .   ? 118.499 106.690 126.249 1.00 45.81  ? 502 PSF A C13 1 
HETATM 6390 C  C14 . PSF D 2 .   ? 118.381 107.608 127.466 1.00 43.35  ? 502 PSF A C14 1 
HETATM 6391 C  C15 . PSF D 2 .   ? 118.848 106.944 128.751 1.00 46.13  ? 502 PSF A C15 1 
HETATM 6392 N  N   . PSF D 2 .   ? 121.877 108.938 117.918 1.00 53.44  ? 502 PSF A N   1 
HETATM 6393 C  CA  . PSF D 2 .   ? 121.702 108.398 119.265 1.00 51.08  ? 502 PSF A CA  1 
HETATM 6394 C  CB  . PSF D 2 .   ? 120.592 107.367 119.215 1.00 49.72  ? 502 PSF A CB  1 
HETATM 6395 C  C   . PSF D 2 .   ? 122.996 107.787 119.834 1.00 53.82  ? 502 PSF A C   1 
HETATM 6396 O  OT1 . PSF D 2 .   ? 123.536 108.430 120.759 1.00 57.74  ? 502 PSF A OT1 1 
HETATM 6397 O  OT2 . PSF D 2 .   ? 123.401 106.720 119.337 1.00 50.35  ? 502 PSF A OT2 1 
HETATM 6398 C  C8  . PSF D 2 .   ? 116.782 102.842 127.689 1.00 52.86  ? 502 PSF A C8  1 
HETATM 6399 C  C9  . PSF D 2 .   ? 116.050 104.054 128.247 1.00 53.24  ? 502 PSF A C9  1 
HETATM 6400 C  C10 . PSF D 2 .   ? 115.880 104.001 129.758 1.00 48.74  ? 502 PSF A C10 1 
HETATM 6401 C  C16 . PSF D 2 .   ? 118.447 107.731 129.989 1.00 51.75  ? 502 PSF A C16 1 
HETATM 6402 C  C17 . PSF D 2 .   ? 119.215 107.296 131.226 1.00 48.71  ? 502 PSF A C17 1 
HETATM 6403 C  C1  . T7X E 3 .   ? 121.089 122.782 125.922 1.00 42.89  ? 503 T7X A C1  1 
HETATM 6404 O  O1  . T7X E 3 .   ? 120.489 121.523 126.096 1.00 49.97  ? 503 T7X A O1  1 
HETATM 6405 P  P1  . T7X E 3 .   ? 119.515 120.810 124.993 1.00 51.35  ? 503 T7X A P1  1 
HETATM 6406 C  C2  . T7X E 3 .   ? 122.232 122.847 126.925 1.00 40.58  ? 503 T7X A C2  1 
HETATM 6407 O  O2  . T7X E 3 .   ? 121.664 122.797 128.206 1.00 41.28  ? 503 T7X A O2  1 
HETATM 6408 C  C3  . T7X E 3 .   ? 123.051 124.120 126.781 1.00 46.74  ? 503 T7X A C3  1 
HETATM 6409 O  O3  . T7X E 3 .   ? 124.177 123.933 127.609 1.00 44.61  ? 503 T7X A O3  1 
HETATM 6410 C  C4  . T7X E 3 .   ? 123.464 124.403 125.343 1.00 51.49  ? 503 T7X A C4  1 
HETATM 6411 O  O4  . T7X E 3 .   ? 124.029 125.692 125.233 1.00 55.64  ? 503 T7X A O4  1 
HETATM 6412 C  C5  . T7X E 3 .   ? 122.253 124.378 124.428 1.00 49.85  ? 503 T7X A C5  1 
HETATM 6413 O  O5  . T7X E 3 .   ? 122.610 124.600 123.088 1.00 54.13  ? 503 T7X A O5  1 
HETATM 6414 C  C6  . T7X E 3 .   ? 121.572 123.021 124.498 1.00 44.96  ? 503 T7X A C6  1 
HETATM 6415 O  O6  . T7X E 3 .   ? 122.454 121.995 124.132 1.00 51.61  ? 503 T7X A O6  1 
HETATM 6416 C  C7  . T7X E 3 .   ? 118.423 120.607 127.367 1.00 42.19  ? 503 T7X A C7  1 
HETATM 6417 C  C8  . T7X E 3 .   ? 117.757 119.676 128.358 1.00 45.34  ? 503 T7X A C8  1 
HETATM 6418 C  C9  . T7X E 3 .   ? 116.743 120.316 129.271 1.00 44.32  ? 503 T7X A C9  1 
HETATM 6419 C  C10 . T7X E 3 .   ? 117.727 117.433 127.586 1.00 52.97  ? 503 T7X A C10 1 
HETATM 6420 C  C11 . T7X E 3 .   ? 114.851 119.395 130.272 1.00 47.44  ? 503 T7X A C11 1 
HETATM 6421 O  O11 . T7X E 3 .   ? 120.280 119.842 124.154 1.00 44.97  ? 503 T7X A O11 1 
HETATM 6422 C  C12 . T7X E 3 .   ? 117.061 116.519 126.600 1.00 45.42  ? 503 T7X A C12 1 
HETATM 6423 O  O12 . T7X E 3 .   ? 118.617 121.820 124.348 1.00 53.98  ? 503 T7X A O12 1 
HETATM 6424 C  C13 . T7X E 3 .   ? 115.552 116.481 126.717 1.00 43.25  ? 503 T7X A C13 1 
HETATM 6425 O  O13 . T7X E 3 .   ? 118.675 119.987 126.132 1.00 42.40  ? 503 T7X A O13 1 
HETATM 6426 C  C14 . T7X E 3 .   ? 115.132 116.075 128.125 1.00 43.79  ? 503 T7X A C14 1 
HETATM 6427 C  C15 . T7X E 3 .   ? 114.517 114.717 128.163 1.00 47.88  ? 503 T7X A C15 1 
HETATM 6428 C  C16 . T7X E 3 .   ? 113.378 114.349 128.740 1.00 49.51  ? 503 T7X A C16 1 
HETATM 6429 O  O16 . T7X E 3 .   ? 117.105 118.601 127.678 1.00 50.99  ? 503 T7X A O16 1 
HETATM 6430 C  C17 . T7X E 3 .   ? 112.804 112.965 128.763 1.00 53.66  ? 503 T7X A C17 1 
HETATM 6431 O  O17 . T7X E 3 .   ? 118.712 117.153 128.216 1.00 55.37  ? 503 T7X A O17 1 
HETATM 6432 C  C18 . T7X E 3 .   ? 113.695 112.102 129.609 1.00 53.53  ? 503 T7X A C18 1 
HETATM 6433 O  O18 . T7X E 3 .   ? 116.152 119.308 130.071 1.00 44.10  ? 503 T7X A O18 1 
HETATM 6434 C  C19 . T7X E 3 .   ? 114.744 111.391 129.196 1.00 52.67  ? 503 T7X A C19 1 
HETATM 6435 O  O19 . T7X E 3 .   ? 114.216 120.367 129.966 1.00 52.92  ? 503 T7X A O19 1 
HETATM 6436 C  C20 . T7X E 3 .   ? 115.660 110.527 130.013 1.00 52.46  ? 503 T7X A C20 1 
HETATM 6437 C  C21 . T7X E 3 .   ? 116.876 111.314 130.402 1.00 53.56  ? 503 T7X A C21 1 
HETATM 6438 C  C22 . T7X E 3 .   ? 117.030 111.931 131.566 1.00 52.44  ? 503 T7X A C22 1 
HETATM 6439 C  C23 . T7X E 3 .   ? 118.234 112.727 131.972 1.00 49.96  ? 503 T7X A C23 1 
HETATM 6440 C  C24 . T7X E 3 .   ? 117.842 114.123 132.362 1.00 53.98  ? 503 T7X A C24 1 
HETATM 6441 C  C25 . T7X E 3 .   ? 116.605 114.539 132.616 1.00 51.78  ? 503 T7X A C25 1 
HETATM 6442 C  C26 . T7X E 3 .   ? 116.235 115.935 133.004 1.00 46.89  ? 503 T7X A C26 1 
HETATM 6443 C  C27 . T7X E 3 .   ? 115.854 116.050 134.479 1.00 42.18  ? 503 T7X A C27 1 
HETATM 6444 C  C31 . T7X E 3 .   ? 114.297 118.160 130.903 1.00 47.98  ? 503 T7X A C31 1 
HETATM 6445 C  C32 . T7X E 3 .   ? 112.852 118.263 131.346 1.00 46.66  ? 503 T7X A C32 1 
HETATM 6446 C  C33 . T7X E 3 .   ? 112.151 116.926 131.174 1.00 45.51  ? 503 T7X A C33 1 
HETATM 6447 C  C34 . T7X E 3 .   ? 111.476 116.423 132.439 1.00 45.20  ? 503 T7X A C34 1 
HETATM 6448 C  C35 . T7X E 3 .   ? 110.142 117.105 132.692 1.00 47.91  ? 503 T7X A C35 1 
HETATM 6449 C  C36 . T7X E 3 .   ? 109.279 116.374 133.711 1.00 47.46  ? 503 T7X A C36 1 
HETATM 6450 C  C37 . T7X E 3 .   ? 109.886 116.328 135.105 1.00 48.02  ? 503 T7X A C37 1 
HETATM 6451 C  C38 . T7X E 3 .   ? 108.918 115.783 136.146 1.00 48.21  ? 503 T7X A C38 1 
HETATM 6452 C  C28 . T7X E 3 .   ? 117.052 116.004 135.417 1.00 40.06  ? 503 T7X A C28 1 
HETATM 6453 C  C1  . LBN F 4 .   ? 130.016 122.671 163.107 1.00 61.66  ? 504 LBN A C1  1 
HETATM 6454 N  N1  . LBN F 4 .   ? 126.680 123.389 168.800 1.00 66.59  ? 504 LBN A N1  1 
HETATM 6455 P  P1  . LBN F 4 .   ? 128.487 122.393 165.220 1.00 88.76  ? 504 LBN A P1  1 
HETATM 6456 C  C2  . LBN F 4 .   ? 129.972 122.583 161.590 1.00 62.08  ? 504 LBN A C2  1 
HETATM 6457 C  C3  . LBN F 4 .   ? 128.769 123.263 160.980 1.00 57.36  ? 504 LBN A C3  1 
HETATM 6458 C  C4  . LBN F 4 .   ? 129.742 124.331 151.649 1.00 58.94  ? 504 LBN A C4  1 
HETATM 6459 C  C5  . LBN F 4 .   ? 128.363 128.248 151.961 1.00 57.70  ? 504 LBN A C5  1 
HETATM 6460 C  C6  . LBN F 4 .   ? 126.601 122.589 167.525 1.00 61.13  ? 504 LBN A C6  1 
HETATM 6461 O  O1  . LBN F 4 .   ? 128.707 122.544 163.610 1.00 70.89  ? 504 LBN A O1  1 
HETATM 6462 C  C7  . LBN F 4 .   ? 130.559 124.813 150.461 1.00 56.59  ? 504 LBN A C7  1 
HETATM 6463 C  C8  . LBN F 4 .   ? 128.665 129.161 150.816 1.00 57.33  ? 504 LBN A C8  1 
HETATM 6464 C  C9  . LBN F 4 .   ? 126.223 123.322 166.257 1.00 58.44  ? 504 LBN A C9  1 
HETATM 6465 O  O2  . LBN F 4 .   ? 126.913 122.881 165.108 1.00 67.58  ? 504 LBN A O2  1 
HETATM 6466 C  C10 . LBN F 4 .   ? 129.765 125.665 149.485 1.00 55.12  ? 504 LBN A C10 1 
HETATM 6467 C  C11 . LBN F 4 .   ? 127.411 129.765 150.185 1.00 58.70  ? 504 LBN A C11 1 
HETATM 6468 C  C12 . LBN F 4 .   ? 127.453 124.652 168.621 1.00 62.04  ? 504 LBN A C12 1 
HETATM 6469 O  O3  . LBN F 4 .   ? 128.542 120.949 165.632 1.00 64.64  ? 504 LBN A O3  1 
HETATM 6470 C  C13 . LBN F 4 .   ? 129.537 124.992 148.141 1.00 53.97  ? 504 LBN A C13 1 
HETATM 6471 C  C14 . LBN F 4 .   ? 127.732 130.931 149.260 1.00 59.63  ? 504 LBN A C14 1 
HETATM 6472 C  C15 . LBN F 4 .   ? 127.299 122.595 169.897 1.00 61.01  ? 504 LBN A C15 1 
HETATM 6473 O  O4  . LBN F 4 .   ? 129.315 123.402 165.953 1.00 63.70  ? 504 LBN A O4  1 
HETATM 6474 C  C16 . LBN F 4 .   ? 128.879 125.910 147.121 1.00 55.48  ? 504 LBN A C16 1 
HETATM 6475 C  C17 . LBN F 4 .   ? 126.522 131.506 148.537 1.00 56.77  ? 504 LBN A C17 1 
HETATM 6476 C  C18 . LBN F 4 .   ? 125.281 123.737 169.180 1.00 62.64  ? 504 LBN A C18 1 
HETATM 6477 C  C19 . LBN F 4 .   ? 127.820 125.205 146.287 1.00 59.54  ? 504 LBN A C19 1 
HETATM 6478 C  C20 . LBN F 4 .   ? 125.452 132.050 149.472 1.00 57.24  ? 504 LBN A C20 1 
HETATM 6479 C  C21 . LBN F 4 .   ? 127.520 125.887 144.959 1.00 61.27  ? 504 LBN A C21 1 
HETATM 6480 C  C22 . LBN F 4 .   ? 124.169 132.444 148.755 1.00 59.03  ? 504 LBN A C22 1 
HETATM 6481 C  C23 . LBN F 4 .   ? 124.224 133.809 148.083 1.00 59.63  ? 504 LBN A C23 1 
HETATM 6482 C  C24 . LBN F 4 .   ? 122.846 134.427 147.914 1.00 55.76  ? 504 LBN A C24 1 
HETATM 6483 C  C25 . LBN F 4 .   ? 126.936 122.730 159.627 1.00 62.87  ? 504 LBN A C25 1 
HETATM 6484 O  O5  . LBN F 4 .   ? 128.164 122.421 160.009 1.00 61.64  ? 504 LBN A O5  1 
HETATM 6485 C  C26 . LBN F 4 .   ? 126.729 122.481 158.163 1.00 58.87  ? 504 LBN A C26 1 
HETATM 6486 O  O6  . LBN F 4 .   ? 126.105 123.171 160.379 1.00 61.71  ? 504 LBN A O6  1 
HETATM 6487 C  C27 . LBN F 4 .   ? 127.793 121.610 157.519 1.00 55.47  ? 504 LBN A C27 1 
HETATM 6488 C  C28 . LBN F 4 .   ? 127.558 121.482 156.022 1.00 59.26  ? 504 LBN A C28 1 
HETATM 6489 C  C29 . LBN F 4 .   ? 128.635 120.680 155.304 1.00 61.51  ? 504 LBN A C29 1 
HETATM 6490 C  C30 . LBN F 4 .   ? 128.603 120.844 153.791 1.00 60.18  ? 504 LBN A C30 1 
HETATM 6491 C  C31 . LBN F 4 .   ? 128.656 122.297 153.338 1.00 62.41  ? 504 LBN A C31 1 
HETATM 6492 C  C32 . LBN F 4 .   ? 129.871 123.050 153.862 1.00 60.92  ? 504 LBN A C32 1 
HETATM 6493 C  C33 . LBN F 4 .   ? 130.614 123.843 152.796 1.00 61.45  ? 504 LBN A C33 1 
HETATM 6494 C  C34 . LBN F 4 .   ? 131.327 124.414 160.779 1.00 65.76  ? 504 LBN A C34 1 
HETATM 6495 O  O7  . LBN F 4 .   ? 131.162 123.107 160.982 1.00 66.49  ? 504 LBN A O7  1 
HETATM 6496 C  C35 . LBN F 4 .   ? 131.609 124.706 159.330 1.00 61.96  ? 504 LBN A C35 1 
HETATM 6497 O  O8  . LBN F 4 .   ? 131.270 125.238 161.654 1.00 63.42  ? 504 LBN A O8  1 
HETATM 6498 C  C36 . LBN F 4 .   ? 131.048 126.029 158.831 1.00 61.00  ? 504 LBN A C36 1 
HETATM 6499 C  C37 . LBN F 4 .   ? 129.525 126.079 158.890 1.00 60.50  ? 504 LBN A C37 1 
HETATM 6500 C  C38 . LBN F 4 .   ? 128.927 127.176 158.022 1.00 59.35  ? 504 LBN A C38 1 
HETATM 6501 C  C39 . LBN F 4 .   ? 128.710 126.750 156.576 1.00 61.37  ? 504 LBN A C39 1 
HETATM 6502 C  C40 . LBN F 4 .   ? 128.708 127.919 155.599 1.00 59.15  ? 504 LBN A C40 1 
HETATM 6503 C  C41 . LBN F 4 .   ? 127.844 127.655 154.365 1.00 59.30  ? 504 LBN A C41 1 
HETATM 6504 C  C42 . LBN F 4 .   ? 128.145 128.583 153.231 1.00 57.39  ? 504 LBN A C42 1 
HETATM 6505 C  C1  . LBN G 4 .   ? 138.529 101.325 146.528 1.00 89.01  ? 505 LBN A C1  1 
HETATM 6506 N  N1  . LBN G 4 .   ? 142.565 99.647  150.865 1.00 93.20  ? 505 LBN A N1  1 
HETATM 6507 P  P1  . LBN G 4 .   ? 140.833 102.435 147.099 1.00 103.46 ? 505 LBN A P1  1 
HETATM 6508 C  C2  . LBN G 4 .   ? 137.358 101.450 145.563 1.00 88.97  ? 505 LBN A C2  1 
HETATM 6509 C  C3  . LBN G 4 .   ? 136.001 101.463 146.226 1.00 90.23  ? 505 LBN A C3  1 
HETATM 6510 C  C6  . LBN G 4 .   ? 141.738 100.572 150.008 1.00 91.79  ? 505 LBN A C6  1 
HETATM 6511 O  O1  . LBN G 4 .   ? 139.650 102.032 146.047 1.00 93.61  ? 505 LBN A O1  1 
HETATM 6512 C  C9  . LBN G 4 .   ? 142.124 100.710 148.552 1.00 88.99  ? 505 LBN A C9  1 
HETATM 6513 O  O2  . LBN G 4 .   ? 141.020 100.913 147.701 1.00 93.23  ? 505 LBN A O2  1 
HETATM 6514 C  C12 . LBN G 4 .   ? 142.425 98.222  150.455 1.00 90.06  ? 505 LBN A C12 1 
HETATM 6515 O  O3  . LBN G 4 .   ? 140.315 103.315 148.199 1.00 91.49  ? 505 LBN A O3  1 
HETATM 6516 C  C15 . LBN G 4 .   ? 142.205 99.771  152.304 1.00 87.66  ? 505 LBN A C15 1 
HETATM 6517 O  O4  . LBN G 4 .   ? 142.068 102.838 146.359 1.00 88.88  ? 505 LBN A O4  1 
HETATM 6518 C  C18 . LBN G 4 .   ? 143.988 100.050 150.690 1.00 91.26  ? 505 LBN A C18 1 
HETATM 6519 C  C25 . LBN G 4 .   ? 134.126 100.277 145.421 1.00 91.00  ? 505 LBN A C25 1 
HETATM 6520 O  O5  . LBN G 4 .   ? 135.329 100.234 145.978 1.00 92.58  ? 505 LBN A O5  1 
HETATM 6521 C  C26 . LBN G 4 .   ? 134.166 99.829  143.989 1.00 89.91  ? 505 LBN A C26 1 
HETATM 6522 O  O6  . LBN G 4 .   ? 133.135 100.632 146.006 1.00 89.31  ? 505 LBN A O6  1 
HETATM 6523 C  C27 . LBN G 4 .   ? 132.808 99.781  143.307 1.00 91.30  ? 505 LBN A C27 1 
HETATM 6524 C  C28 . LBN G 4 .   ? 132.766 98.725  142.209 1.00 92.93  ? 505 LBN A C28 1 
HETATM 6525 C  C29 . LBN G 4 .   ? 133.839 98.909  141.145 1.00 90.97  ? 505 LBN A C29 1 
HETATM 6526 C  C30 . LBN G 4 .   ? 133.663 100.181 140.327 1.00 88.54  ? 505 LBN A C30 1 
HETATM 6527 C  C34 . LBN G 4 .   ? 137.587 102.534 143.443 1.00 92.40  ? 505 LBN A C34 1 
HETATM 6528 O  O7  . LBN G 4 .   ? 137.457 102.635 144.767 1.00 90.00  ? 505 LBN A O7  1 
HETATM 6529 C  C35 . LBN G 4 .   ? 136.255 102.653 142.750 1.00 87.72  ? 505 LBN A C35 1 
HETATM 6530 O  O8  . LBN G 4 .   ? 138.648 102.375 142.893 1.00 91.97  ? 505 LBN A O8  1 
HETATM 6531 C  C36 . LBN G 4 .   ? 136.317 102.561 141.234 1.00 86.87  ? 505 LBN A C36 1 
HETATM 6532 C  C37 . LBN G 4 .   ? 136.967 103.783 140.594 1.00 86.89  ? 505 LBN A C37 1 
HETATM 6533 C  C38 . LBN G 4 .   ? 135.996 104.607 139.759 1.00 86.58  ? 505 LBN A C38 1 
HETATM 6534 C  C39 . LBN G 4 .   ? 135.128 103.768 138.832 1.00 88.88  ? 505 LBN A C39 1 
HETATM 6535 C  C40 . LBN G 4 .   ? 134.329 104.599 137.837 1.00 85.50  ? 505 LBN A C40 1 
HETATM 6536 C  C41 . LBN G 4 .   ? 133.286 105.500 138.498 1.00 85.25  ? 505 LBN A C41 1 
HETATM 6537 C  C1  . D12 H 5 .   ? 132.333 97.779  153.984 1.00 75.86  ? 506 D12 A C1  1 
HETATM 6538 C  C2  . D12 H 5 .   ? 132.651 98.115  152.534 1.00 79.45  ? 506 D12 A C2  1 
HETATM 6539 C  C3  . D12 H 5 .   ? 131.510 98.843  151.835 1.00 77.70  ? 506 D12 A C3  1 
HETATM 6540 C  C4  . D12 H 5 .   ? 131.808 99.162  150.376 1.00 76.90  ? 506 D12 A C4  1 
HETATM 6541 C  C5  . D12 H 5 .   ? 130.569 99.563  149.589 1.00 74.29  ? 506 D12 A C5  1 
HETATM 6542 C  C6  . D12 H 5 .   ? 130.836 99.717  148.098 1.00 75.32  ? 506 D12 A C6  1 
HETATM 6543 C  C7  . D12 H 5 .   ? 129.606 100.136 147.305 1.00 75.88  ? 506 D12 A C7  1 
HETATM 6544 C  C8  . D12 H 5 .   ? 129.850 100.158 145.802 1.00 78.14  ? 506 D12 A C8  1 
HETATM 6545 C  C9  . D12 H 5 .   ? 128.763 100.876 145.015 1.00 77.72  ? 506 D12 A C9  1 
HETATM 6546 C  C10 . D12 H 5 .   ? 129.158 101.129 143.567 1.00 74.75  ? 506 D12 A C10 1 
HETATM 6547 C  C11 . D12 H 5 .   ? 128.126 101.933 142.786 1.00 75.52  ? 506 D12 A C11 1 
HETATM 6548 C  C12 . D12 H 5 .   ? 128.532 102.150 141.335 1.00 77.12  ? 506 D12 A C12 1 
HETATM 6549 C  C01 . C14 I 6 .   ? 130.116 110.167 138.224 1.00 53.32  ? 507 C14 A C01 1 
HETATM 6550 C  C02 . C14 I 6 .   ? 129.764 109.356 139.460 1.00 56.19  ? 507 C14 A C02 1 
HETATM 6551 C  C03 . C14 I 6 .   ? 129.165 110.209 140.570 1.00 58.41  ? 507 C14 A C03 1 
HETATM 6552 C  C04 . C14 I 6 .   ? 128.710 109.388 141.768 1.00 55.00  ? 507 C14 A C04 1 
HETATM 6553 C  C05 . C14 I 6 .   ? 128.710 110.161 143.079 1.00 56.18  ? 507 C14 A C05 1 
HETATM 6554 C  C06 . C14 I 6 .   ? 129.258 109.337 144.235 1.00 59.34  ? 507 C14 A C06 1 
HETATM 6555 C  C07 . C14 I 6 .   ? 128.626 109.670 145.578 1.00 60.09  ? 507 C14 A C07 1 
HETATM 6556 C  C08 . C14 I 6 .   ? 128.294 108.425 146.391 1.00 59.75  ? 507 C14 A C08 1 
HETATM 6557 C  C09 . C14 I 6 .   ? 127.829 108.726 147.809 1.00 58.86  ? 507 C14 A C09 1 
HETATM 6558 C  C10 . C14 I 6 .   ? 127.506 107.470 148.608 1.00 55.25  ? 507 C14 A C10 1 
HETATM 6559 C  C11 . C14 I 6 .   ? 127.120 107.763 150.050 1.00 58.27  ? 507 C14 A C11 1 
HETATM 6560 C  C12 . C14 I 6 .   ? 126.547 106.555 150.779 1.00 57.94  ? 507 C14 A C12 1 
HETATM 6561 C  C13 . C14 I 6 .   ? 126.175 106.848 152.227 1.00 57.63  ? 507 C14 A C13 1 
HETATM 6562 C  C14 . C14 I 6 .   ? 125.687 105.616 152.975 1.00 59.77  ? 507 C14 A C14 1 
HETATM 6563 C  C1  . LBN J 4 .   ? 150.367 121.745 124.356 1.00 44.35  ? 508 LBN A C1  1 
HETATM 6564 N  N1  . LBN J 4 .   ? 146.454 123.777 120.609 1.00 45.91  ? 508 LBN A N1  1 
HETATM 6565 P  P1  . LBN J 4 .   ? 150.081 123.909 122.922 1.00 69.24  ? 508 LBN A P1  1 
HETATM 6566 C  C2  . LBN J 4 .   ? 149.810 122.147 125.714 1.00 44.01  ? 508 LBN A C2  1 
HETATM 6567 C  C3  . LBN J 4 .   ? 149.227 121.020 126.532 1.00 47.03  ? 508 LBN A C3  1 
HETATM 6568 C  C4  . LBN J 4 .   ? 143.931 117.312 133.600 1.00 37.99  ? 508 LBN A C4  1 
HETATM 6569 C  C5  . LBN J 4 .   ? 156.727 121.036 136.185 1.00 51.45  ? 508 LBN A C5  1 
HETATM 6570 C  C6  . LBN J 4 .   ? 147.303 122.545 120.736 1.00 45.84  ? 508 LBN A C6  1 
HETATM 6571 O  O1  . LBN J 4 .   ? 150.996 122.850 123.754 1.00 51.83  ? 508 LBN A O1  1 
HETATM 6572 C  C7  . LBN J 4 .   ? 144.777 116.058 133.758 1.00 39.59  ? 508 LBN A C7  1 
HETATM 6573 C  C8  . LBN J 4 .   ? 157.647 120.299 137.107 1.00 47.26  ? 508 LBN A C8  1 
HETATM 6574 C  C9  . LBN J 4 .   ? 148.775 122.737 121.007 1.00 51.64  ? 508 LBN A C9  1 
HETATM 6575 O  O2  . LBN J 4 .   ? 149.073 122.732 122.381 1.00 50.67  ? 508 LBN A O2  1 
HETATM 6576 C  C10 . LBN J 4 .   ? 143.973 114.771 133.692 1.00 39.70  ? 508 LBN A C10 1 
HETATM 6577 C  C11 . LBN J 4 .   ? 157.020 120.152 138.494 1.00 47.27  ? 508 LBN A C11 1 
HETATM 6578 C  C12 . LBN J 4 .   ? 146.804 124.827 121.602 1.00 43.00  ? 508 LBN A C12 1 
HETATM 6579 O  O3  . LBN J 4 .   ? 149.314 124.817 123.833 1.00 55.61  ? 508 LBN A O3  1 
HETATM 6580 C  C13 . LBN J 4 .   ? 144.572 113.659 134.539 1.00 41.28  ? 508 LBN A C13 1 
HETATM 6581 C  C14 . LBN J 4 .   ? 158.041 120.070 139.621 1.00 50.31  ? 508 LBN A C14 1 
HETATM 6582 C  C15 . LBN J 4 .   ? 145.018 123.435 120.760 1.00 46.90  ? 508 LBN A C15 1 
HETATM 6583 O  O4  . LBN J 4 .   ? 150.858 124.490 121.786 1.00 50.61  ? 508 LBN A O4  1 
HETATM 6584 C  C16 . LBN J 4 .   ? 143.740 112.388 134.548 1.00 37.89  ? 508 LBN A C16 1 
HETATM 6585 C  C17 . LBN J 4 .   ? 157.408 119.767 140.973 1.00 49.07  ? 508 LBN A C17 1 
HETATM 6586 C  C18 . LBN J 4 .   ? 146.685 124.334 119.251 1.00 46.89  ? 508 LBN A C18 1 
HETATM 6587 C  C19 . LBN J 4 .   ? 144.421 111.254 135.296 1.00 38.80  ? 508 LBN A C19 1 
HETATM 6588 C  C20 . LBN J 4 .   ? 158.383 119.205 142.002 1.00 50.69  ? 508 LBN A C20 1 
HETATM 6589 C  C21 . LBN J 4 .   ? 143.733 109.917 135.087 1.00 42.52  ? 508 LBN A C21 1 
HETATM 6590 C  C22 . LBN J 4 .   ? 157.843 119.222 143.426 1.00 54.18  ? 508 LBN A C22 1 
HETATM 6591 C  C23 . LBN J 4 .   ? 156.321 119.171 143.502 1.00 51.29  ? 508 LBN A C23 1 
HETATM 6592 C  C24 . LBN J 4 .   ? 155.764 119.725 144.807 1.00 46.78  ? 508 LBN A C24 1 
HETATM 6593 C  C25 . LBN J 4 .   ? 148.023 122.245 128.137 1.00 46.94  ? 508 LBN A C25 1 
HETATM 6594 O  O5  . LBN J 4 .   ? 149.058 121.471 127.865 1.00 51.01  ? 508 LBN A O5  1 
HETATM 6595 C  C26 . LBN J 4 .   ? 146.841 121.446 128.579 1.00 45.11  ? 508 LBN A C26 1 
HETATM 6596 O  O6  . LBN J 4 .   ? 148.042 123.443 128.045 1.00 49.61  ? 508 LBN A O6  1 
HETATM 6597 C  C27 . LBN J 4 .   ? 145.945 122.182 129.559 1.00 47.53  ? 508 LBN A C27 1 
HETATM 6598 C  C28 . LBN J 4 .   ? 146.622 122.380 130.905 1.00 43.53  ? 508 LBN A C28 1 
HETATM 6599 C  C29 . LBN J 4 .   ? 145.662 122.904 131.961 1.00 44.38  ? 508 LBN A C29 1 
HETATM 6600 C  C30 . LBN J 4 .   ? 144.555 121.922 132.315 1.00 41.85  ? 508 LBN A C30 1 
HETATM 6601 C  C31 . LBN J 4 .   ? 144.888 121.055 133.521 1.00 47.43  ? 508 LBN A C31 1 
HETATM 6602 C  C32 . LBN J 4 .   ? 143.958 119.863 133.682 1.00 43.12  ? 508 LBN A C32 1 
HETATM 6603 C  C33 . LBN J 4 .   ? 144.697 118.568 133.985 1.00 43.84  ? 508 LBN A C33 1 
HETATM 6604 C  C34 . LBN J 4 .   ? 151.954 122.373 126.841 1.00 47.34  ? 508 LBN A C34 1 
HETATM 6605 O  O7  . LBN J 4 .   ? 150.754 122.858 126.528 1.00 46.13  ? 508 LBN A O7  1 
HETATM 6606 C  C35 . LBN J 4 .   ? 152.834 123.435 127.431 1.00 47.61  ? 508 LBN A C35 1 
HETATM 6607 O  O8  . LBN J 4 .   ? 152.298 121.236 126.682 1.00 52.99  ? 508 LBN A O8  1 
HETATM 6608 C  C36 . LBN J 4 .   ? 153.983 122.887 128.255 1.00 47.74  ? 508 LBN A C36 1 
HETATM 6609 C  C37 . LBN J 4 .   ? 153.533 122.430 129.636 1.00 42.92  ? 508 LBN A C37 1 
HETATM 6610 C  C38 . LBN J 4 .   ? 154.701 122.030 130.526 1.00 40.28  ? 508 LBN A C38 1 
HETATM 6611 C  C39 . LBN J 4 .   ? 154.311 121.885 131.989 1.00 43.22  ? 508 LBN A C39 1 
HETATM 6612 C  C40 . LBN J 4 .   ? 155.402 121.279 132.857 1.00 43.39  ? 508 LBN A C40 1 
HETATM 6613 C  C41 . LBN J 4 .   ? 155.024 121.325 134.336 1.00 47.60  ? 508 LBN A C41 1 
HETATM 6614 C  C42 . LBN J 4 .   ? 155.939 120.545 135.227 1.00 50.68  ? 508 LBN A C42 1 
HETATM 6615 CA CA  . CA  K 7 .   ? 148.065 101.263 146.645 1.00 68.88  ? 509 CA  A CA  1 
HETATM 6616 C  C1  . LBN L 4 .   ? 123.308 109.229 155.644 1.00 61.39  ? 510 LBN A C1  1 
HETATM 6617 N  N1  . LBN L 4 .   ? 123.676 114.055 159.098 1.00 61.25  ? 510 LBN A N1  1 
HETATM 6618 P  P1  . LBN L 4 .   ? 123.283 109.446 158.248 1.00 87.07  ? 510 LBN A P1  1 
HETATM 6619 C  C2  . LBN L 4 .   ? 124.589 109.323 154.833 1.00 65.25  ? 510 LBN A C2  1 
HETATM 6620 C  C3  . LBN L 4 .   ? 124.494 110.237 153.636 1.00 66.00  ? 510 LBN A C3  1 
HETATM 6621 C  C4  . LBN L 4 .   ? 124.415 112.747 143.662 1.00 63.63  ? 510 LBN A C4  1 
HETATM 6622 C  C5  . LBN L 4 .   ? 130.820 111.858 148.840 1.00 62.52  ? 510 LBN A C5  1 
HETATM 6623 C  C6  . LBN L 4 .   ? 122.421 113.229 159.042 1.00 64.02  ? 510 LBN A C6  1 
HETATM 6624 O  O1  . LBN L 4 .   ? 123.366 110.094 156.754 1.00 63.93  ? 510 LBN A O1  1 
HETATM 6625 C  C7  . LBN L 4 .   ? 124.485 111.868 142.418 1.00 64.39  ? 510 LBN A C7  1 
HETATM 6626 C  C8  . LBN L 4 .   ? 131.758 113.004 149.054 1.00 62.08  ? 510 LBN A C8  1 
HETATM 6627 C  C9  . LBN L 4 .   ? 122.471 111.921 158.290 1.00 64.15  ? 510 LBN A C9  1 
HETATM 6628 O  O2  . LBN L 4 .   ? 123.202 110.926 158.966 1.00 71.09  ? 510 LBN A O2  1 
HETATM 6629 C  C10 . LBN L 4 .   ? 123.379 112.177 141.417 1.00 65.88  ? 510 LBN A C10 1 
HETATM 6630 C  C11 . LBN L 4 .   ? 132.834 113.106 147.973 1.00 64.17  ? 510 LBN A C11 1 
HETATM 6631 C  C12 . LBN L 4 .   ? 123.371 115.495 159.305 1.00 60.66  ? 510 LBN A C12 1 
HETATM 6632 O  O3  . LBN L 4 .   ? 121.974 108.741 158.454 1.00 70.98  ? 510 LBN A O3  1 
HETATM 6633 C  C13 . LBN L 4 .   ? 123.658 111.689 140.000 1.00 63.72  ? 510 LBN A C13 1 
HETATM 6634 C  C14 . LBN L 4 .   ? 132.478 114.056 146.836 1.00 61.13  ? 510 LBN A C14 1 
HETATM 6635 C  C15 . LBN L 4 .   ? 124.489 113.899 157.862 1.00 58.20  ? 510 LBN A C15 1 
HETATM 6636 O  O4  . LBN L 4 .   ? 124.561 108.758 158.614 1.00 66.45  ? 510 LBN A O4  1 
HETATM 6637 C  C16 . LBN L 4 .   ? 124.978 112.183 139.426 1.00 62.37  ? 510 LBN A C16 1 
HETATM 6638 C  C17 . LBN L 4 .   ? 131.385 113.533 145.914 1.00 64.56  ? 510 LBN A C17 1 
HETATM 6639 C  C18 . LBN L 4 .   ? 124.465 113.573 160.264 1.00 63.31  ? 510 LBN A C18 1 
HETATM 6640 C  C19 . LBN L 4 .   ? 125.166 111.858 137.950 1.00 60.95  ? 510 LBN A C19 1 
HETATM 6641 C  C20 . LBN L 4 .   ? 130.805 114.590 144.982 1.00 61.01  ? 510 LBN A C20 1 
HETATM 6642 C  C21 . LBN L 4 .   ? 124.490 110.566 137.517 1.00 60.59  ? 510 LBN A C21 1 
HETATM 6643 C  C22 . LBN L 4 .   ? 130.772 115.985 145.590 1.00 61.84  ? 510 LBN A C22 1 
HETATM 6644 C  C23 . LBN L 4 .   ? 129.610 116.833 145.096 1.00 57.85  ? 510 LBN A C23 1 
HETATM 6645 C  C24 . LBN L 4 .   ? 128.293 116.460 145.754 1.00 57.52  ? 510 LBN A C24 1 
HETATM 6646 C  C25 . LBN L 4 .   ? 122.975 110.576 151.852 1.00 65.80  ? 510 LBN A C25 1 
HETATM 6647 O  O5  . LBN L 4 .   ? 123.474 109.759 152.769 1.00 67.67  ? 510 LBN A O5  1 
HETATM 6648 C  C26 . LBN L 4 .   ? 124.052 111.197 151.010 1.00 63.04  ? 510 LBN A C26 1 
HETATM 6649 O  O6  . LBN L 4 .   ? 121.793 110.775 151.720 1.00 64.43  ? 510 LBN A O6  1 
HETATM 6650 C  C27 . LBN L 4 .   ? 123.526 111.930 149.788 1.00 62.77  ? 510 LBN A C27 1 
HETATM 6651 C  C28 . LBN L 4 .   ? 124.617 112.179 148.756 1.00 66.56  ? 510 LBN A C28 1 
HETATM 6652 C  C29 . LBN L 4 .   ? 125.716 113.120 149.233 1.00 66.92  ? 510 LBN A C29 1 
HETATM 6653 C  C30 . LBN L 4 .   ? 126.265 114.025 148.135 1.00 64.92  ? 510 LBN A C30 1 
HETATM 6654 C  C31 . LBN L 4 .   ? 126.597 113.302 146.835 1.00 64.58  ? 510 LBN A C31 1 
HETATM 6655 C  C32 . LBN L 4 .   ? 125.654 113.652 145.690 1.00 63.66  ? 510 LBN A C32 1 
HETATM 6656 C  C33 . LBN L 4 .   ? 125.609 112.593 144.594 1.00 65.23  ? 510 LBN A C33 1 
HETATM 6657 C  C34 . LBN L 4 .   ? 126.471 108.878 156.231 1.00 68.80  ? 510 LBN A C34 1 
HETATM 6658 O  O7  . LBN L 4 .   ? 125.686 109.773 155.634 1.00 69.68  ? 510 LBN A O7  1 
HETATM 6659 C  C35 . LBN L 4 .   ? 127.600 109.551 156.959 1.00 64.27  ? 510 LBN A C35 1 
HETATM 6660 O  O8  . LBN L 4 .   ? 126.288 107.688 156.185 1.00 67.08  ? 510 LBN A O8  1 
HETATM 6661 C  C36 . LBN L 4 .   ? 128.364 110.531 156.087 1.00 63.70  ? 510 LBN A C36 1 
HETATM 6662 C  C37 . LBN L 4 .   ? 128.824 109.878 154.793 1.00 63.36  ? 510 LBN A C37 1 
HETATM 6663 C  C38 . LBN L 4 .   ? 128.180 110.494 153.562 1.00 60.12  ? 510 LBN A C38 1 
HETATM 6664 C  C39 . LBN L 4 .   ? 128.710 111.885 153.250 1.00 62.55  ? 510 LBN A C39 1 
HETATM 6665 C  C40 . LBN L 4 .   ? 128.922 112.103 151.760 1.00 59.96  ? 510 LBN A C40 1 
HETATM 6666 C  C41 . LBN L 4 .   ? 130.181 111.405 151.249 1.00 58.25  ? 510 LBN A C41 1 
HETATM 6667 C  C42 . LBN L 4 .   ? 130.151 111.183 149.771 1.00 64.78  ? 510 LBN A C42 1 
HETATM 6668 N  N   . SER M 8 .   ? 146.081 105.727 148.390 1.00 72.78  ? 511 SER A N   1 
HETATM 6669 C  CA  . SER M 8 .   ? 145.030 104.884 147.836 1.00 77.81  ? 511 SER A CA  1 
HETATM 6670 C  C   . SER M 8 .   ? 145.497 103.437 147.707 1.00 80.49  ? 511 SER A C   1 
HETATM 6671 O  O   . SER M 8 .   ? 146.499 103.147 147.053 1.00 79.88  ? 511 SER A O   1 
HETATM 6672 C  CB  . SER M 8 .   ? 144.581 105.416 146.474 1.00 74.92  ? 511 SER A CB  1 
HETATM 6673 O  OG  . SER M 8 .   ? 143.569 104.599 145.914 1.00 76.11  ? 511 SER A OG  1 
HETATM 6674 O  OXT . SER M 8 .   ? 144.881 102.520 148.251 1.00 78.42  ? 511 SER A OXT 1 
HETATM 6675 C  C1  . LBN N 4 .   ? 104.355 121.885 128.957 1.00 49.61  ? 512 LBN A C1  1 
HETATM 6676 N  N1  . LBN N 4 .   ? 110.117 124.300 126.310 1.00 47.26  ? 512 LBN A N1  1 
HETATM 6677 P  P1  . LBN N 4 .   ? 106.599 122.003 127.654 1.00 53.40  ? 512 LBN A P1  1 
HETATM 6678 C  C2  . LBN N 4 .   ? 103.830 123.243 129.376 1.00 50.19  ? 512 LBN A C2  1 
HETATM 6679 C  C3  . LBN N 4 .   ? 103.285 124.051 128.224 1.00 52.64  ? 512 LBN A C3  1 
HETATM 6680 C  C4  . LBN N 4 .   ? 104.468 127.203 137.366 1.00 50.39  ? 512 LBN A C4  1 
HETATM 6681 C  C6  . LBN N 4 .   ? 109.027 123.705 127.148 1.00 46.55  ? 512 LBN A C6  1 
HETATM 6682 O  O1  . LBN N 4 .   ? 104.976 122.027 127.705 1.00 56.81  ? 512 LBN A O1  1 
HETATM 6683 C  C7  . LBN N 4 .   ? 103.484 127.584 138.461 1.00 51.73  ? 512 LBN A C7  1 
HETATM 6684 C  C9  . LBN N 4 .   ? 107.650 124.251 126.879 1.00 49.99  ? 512 LBN A C9  1 
HETATM 6685 O  O2  . LBN N 4 .   ? 106.658 123.637 127.655 1.00 50.66  ? 512 LBN A O2  1 
HETATM 6686 C  C10 . LBN N 4 .   ? 103.449 126.582 139.602 1.00 52.78  ? 512 LBN A C10 1 
HETATM 6687 C  C12 . LBN N 4 .   ? 111.430 123.649 126.525 1.00 48.33  ? 512 LBN A C12 1 
HETATM 6688 O  O3  . LBN N 4 .   ? 107.191 121.525 128.939 1.00 45.64  ? 512 LBN A O3  1 
HETATM 6689 C  C13 . LBN N 4 .   ? 102.112 125.865 139.721 1.00 54.36  ? 512 LBN A C13 1 
HETATM 6690 C  C15 . LBN N 4 .   ? 110.239 125.750 126.600 1.00 49.04  ? 512 LBN A C15 1 
HETATM 6691 O  O4  . LBN N 4 .   ? 107.071 121.450 126.351 1.00 55.17  ? 512 LBN A O4  1 
HETATM 6692 C  C16 . LBN N 4 .   ? 101.567 125.865 141.141 1.00 53.51  ? 512 LBN A C16 1 
HETATM 6693 C  C18 . LBN N 4 .   ? 109.720 124.093 124.895 1.00 50.35  ? 512 LBN A C18 1 
HETATM 6694 C  C19 . LBN N 4 .   ? 101.587 127.244 141.788 1.00 52.59  ? 512 LBN A C19 1 
HETATM 6695 C  C21 . LBN N 4 .   ? 100.551 128.195 141.209 1.00 53.56  ? 512 LBN A C21 1 
HETATM 6696 C  C25 . LBN N 4 .   ? 103.195 126.399 127.975 1.00 58.48  ? 512 LBN A C25 1 
HETATM 6697 O  O5  . LBN N 4 .   ? 102.916 125.333 128.708 1.00 62.93  ? 512 LBN A O5  1 
HETATM 6698 C  C26 . LBN N 4 .   ? 102.830 127.655 128.705 1.00 52.42  ? 512 LBN A C26 1 
HETATM 6699 O  O6  . LBN N 4 .   ? 103.678 126.346 126.871 1.00 55.84  ? 512 LBN A O6  1 
HETATM 6700 C  C27 . LBN N 4 .   ? 103.234 127.655 130.168 1.00 46.45  ? 512 LBN A C27 1 
HETATM 6701 C  C28 . LBN N 4 .   ? 102.018 127.656 131.078 1.00 47.24  ? 512 LBN A C28 1 
HETATM 6702 C  C29 . LBN N 4 .   ? 102.280 128.300 132.431 1.00 55.29  ? 512 LBN A C29 1 
HETATM 6703 C  C30 . LBN N 4 .   ? 103.110 127.427 133.360 1.00 55.24  ? 512 LBN A C30 1 
HETATM 6704 C  C31 . LBN N 4 .   ? 104.516 127.961 133.592 1.00 55.80  ? 512 LBN A C31 1 
HETATM 6705 C  C32 . LBN N 4 .   ? 105.104 127.534 134.928 1.00 52.29  ? 512 LBN A C32 1 
HETATM 6706 C  C33 . LBN N 4 .   ? 104.296 128.044 136.111 1.00 52.01  ? 512 LBN A C33 1 
HETATM 6707 C  C34 . LBN N 4 .   ? 103.144 123.070 131.648 1.00 52.04  ? 512 LBN A C34 1 
HETATM 6708 O  O7  . LBN N 4 .   ? 102.806 123.132 130.364 1.00 56.23  ? 512 LBN A O7  1 
HETATM 6709 C  C35 . LBN N 4 .   ? 101.993 123.448 132.534 1.00 49.73  ? 512 LBN A C35 1 
HETATM 6710 O  O8  . LBN N 4 .   ? 104.234 122.749 132.036 1.00 54.75  ? 512 LBN A O8  1 
HETATM 6711 C  C36 . LBN N 4 .   ? 102.345 123.440 134.010 1.00 53.80  ? 512 LBN A C36 1 
HETATM 6712 C  C37 . LBN N 4 .   ? 101.268 124.110 134.857 1.00 54.76  ? 512 LBN A C37 1 
HETATM 6713 C  C1  . LBN O 4 .   ? 148.842 131.315 128.956 1.00 49.46  ? 501 LBN B C1  1 
HETATM 6714 N  N1  . LBN O 4 .   ? 143.087 128.903 126.327 1.00 46.06  ? 501 LBN B N1  1 
HETATM 6715 P  P1  . LBN O 4 .   ? 146.605 131.186 127.638 1.00 51.20  ? 501 LBN B P1  1 
HETATM 6716 C  C2  . LBN O 4 .   ? 149.375 129.961 129.378 1.00 49.92  ? 501 LBN B C2  1 
HETATM 6717 C  C3  . LBN O 4 .   ? 149.922 129.153 128.228 1.00 51.94  ? 501 LBN B C3  1 
HETATM 6718 C  C4  . LBN O 4 .   ? 148.724 126.030 137.349 1.00 49.32  ? 501 LBN B C4  1 
HETATM 6719 C  C6  . LBN O 4 .   ? 144.180 129.488 127.168 1.00 46.88  ? 501 LBN B C6  1 
HETATM 6720 O  O1  . LBN O 4 .   ? 148.228 131.169 127.701 1.00 55.60  ? 501 LBN B O1  1 
HETATM 6721 C  C7  . LBN O 4 .   ? 149.648 125.600 138.477 1.00 51.04  ? 501 LBN B C7  1 
HETATM 6722 C  C9  . LBN O 4 .   ? 145.551 128.927 126.902 1.00 50.31  ? 501 LBN B C9  1 
HETATM 6723 O  O2  . LBN O 4 .   ? 146.553 129.551 127.655 1.00 50.57  ? 501 LBN B O2  1 
HETATM 6724 C  C10 . LBN O 4 .   ? 149.700 126.601 139.618 1.00 50.92  ? 501 LBN B C10 1 
HETATM 6725 C  C12 . LBN O 4 .   ? 141.774 129.549 126.558 1.00 46.20  ? 501 LBN B C12 1 
HETATM 6726 O  O3  . LBN O 4 .   ? 146.000 131.672 128.914 1.00 44.29  ? 501 LBN B O3  1 
HETATM 6727 C  C13 . LBN O 4 .   ? 151.031 127.334 139.701 1.00 52.93  ? 501 LBN B C13 1 
HETATM 6728 C  C15 . LBN O 4 .   ? 142.969 127.449 126.598 1.00 46.78  ? 501 LBN B C15 1 
HETATM 6729 O  O4  . LBN O 4 .   ? 146.141 131.724 126.327 1.00 55.50  ? 501 LBN B O4  1 
HETATM 6730 C  C16 . LBN O 4 .   ? 151.606 127.351 141.109 1.00 53.21  ? 501 LBN B C16 1 
HETATM 6731 C  C18 . LBN O 4 .   ? 143.479 129.130 124.913 1.00 50.73  ? 501 LBN B C18 1 
HETATM 6732 C  C19 . LBN O 4 .   ? 151.595 125.981 141.776 1.00 52.97  ? 501 LBN B C19 1 
HETATM 6733 C  C21 . LBN O 4 .   ? 152.620 125.019 141.193 1.00 52.33  ? 501 LBN B C21 1 
HETATM 6734 C  C25 . LBN O 4 .   ? 149.975 126.805 127.982 1.00 58.34  ? 501 LBN B C25 1 
HETATM 6735 O  O5  . LBN O 4 .   ? 150.280 127.867 128.710 1.00 62.35  ? 501 LBN B O5  1 
HETATM 6736 C  C26 . LBN O 4 .   ? 150.331 125.545 128.710 1.00 51.18  ? 501 LBN B C26 1 
HETATM 6737 O  O6  . LBN O 4 .   ? 149.479 126.863 126.884 1.00 55.52  ? 501 LBN B O6  1 
HETATM 6738 C  C27 . LBN O 4 .   ? 149.950 125.545 130.178 1.00 45.86  ? 501 LBN B C27 1 
HETATM 6739 C  C28 . LBN O 4 .   ? 151.181 125.544 131.070 1.00 47.24  ? 501 LBN B C28 1 
HETATM 6740 C  C29 . LBN O 4 .   ? 150.941 124.894 132.423 1.00 54.70  ? 501 LBN B C29 1 
HETATM 6741 C  C30 . LBN O 4 .   ? 150.124 125.760 133.371 1.00 54.33  ? 501 LBN B C30 1 
HETATM 6742 C  C31 . LBN O 4 .   ? 148.706 125.249 133.584 1.00 55.85  ? 501 LBN B C31 1 
HETATM 6743 C  C32 . LBN O 4 .   ? 148.104 125.693 134.908 1.00 51.13  ? 501 LBN B C32 1 
HETATM 6744 C  C33 . LBN O 4 .   ? 148.879 125.168 136.107 1.00 50.86  ? 501 LBN B C33 1 
HETATM 6745 C  C34 . LBN O 4 .   ? 150.069 130.134 131.647 1.00 51.55  ? 501 LBN B C34 1 
HETATM 6746 O  O7  . LBN O 4 .   ? 150.402 130.083 130.362 1.00 55.98  ? 501 LBN B O7  1 
HETATM 6747 C  C35 . LBN O 4 .   ? 151.221 129.738 132.523 1.00 50.01  ? 501 LBN B C35 1 
HETATM 6748 O  O8  . LBN O 4 .   ? 148.983 130.459 132.042 1.00 53.83  ? 501 LBN B O8  1 
HETATM 6749 C  C36 . LBN O 4 .   ? 150.886 129.766 134.003 1.00 52.97  ? 501 LBN B C36 1 
HETATM 6750 C  C37 . LBN O 4 .   ? 151.947 129.064 134.842 1.00 52.89  ? 501 LBN B C37 1 
HETATM 6751 O  O2  . PSF P 2 .   ? 122.334 145.590 125.161 1.00 39.94  ? 502 PSF B O2  1 
HETATM 6752 O  O1  . PSF P 2 .   ? 121.855 143.889 123.412 1.00 41.02  ? 502 PSF B O1  1 
HETATM 6753 P  P   . PSF P 2 .   ? 123.109 144.729 124.016 1.00 43.50  ? 502 PSF B P   1 
HETATM 6754 O  O4  . PSF P 2 .   ? 123.561 145.715 122.997 1.00 37.15  ? 502 PSF B O4  1 
HETATM 6755 O  O3  . PSF P 2 .   ? 124.084 143.801 124.662 1.00 56.31  ? 502 PSF B O3  1 
HETATM 6756 C  C2  . PSF P 2 .   ? 123.059 146.125 126.243 1.00 37.84  ? 502 PSF B C2  1 
HETATM 6757 C  C3  . PSF P 2 .   ? 122.209 146.045 127.494 1.00 36.25  ? 502 PSF B C3  1 
HETATM 6758 O  O11 . PSF P 2 .   ? 121.076 146.907 127.399 1.00 44.71  ? 502 PSF B O11 1 
HETATM 6759 O  O12 . PSF P 2 .   ? 119.805 146.122 129.058 1.00 41.32  ? 502 PSF B O12 1 
HETATM 6760 C  C1  . PSF P 2 .   ? 120.256 147.048 128.437 1.00 44.14  ? 502 PSF B C1  1 
HETATM 6761 C  C4  . PSF P 2 .   ? 122.987 146.503 128.701 1.00 39.58  ? 502 PSF B C4  1 
HETATM 6762 C  C5  . PSF P 2 .   ? 124.212 148.469 128.949 1.00 42.15  ? 502 PSF B C5  1 
HETATM 6763 O  O51 . PSF P 2 .   ? 123.655 149.492 128.659 1.00 48.18  ? 502 PSF B O51 1 
HETATM 6764 O  O52 . PSF P 2 .   ? 124.049 147.345 128.268 1.00 42.47  ? 502 PSF B O52 1 
HETATM 6765 C  C6  . PSF P 2 .   ? 125.130 148.289 130.121 1.00 41.59  ? 502 PSF B C6  1 
HETATM 6766 C  C7  . PSF P 2 .   ? 124.609 148.949 131.383 1.00 45.71  ? 502 PSF B C7  1 
HETATM 6767 C  C13 . PSF P 2 .   ? 119.972 148.499 128.710 1.00 45.22  ? 502 PSF B C13 1 
HETATM 6768 C  C14 . PSF P 2 .   ? 119.189 148.711 130.011 1.00 44.50  ? 502 PSF B C14 1 
HETATM 6769 C  C15 . PSF P 2 .   ? 120.057 148.836 131.257 1.00 40.56  ? 502 PSF B C15 1 
HETATM 6770 N  N   . PSF P 2 .   ? 119.245 143.625 120.995 1.00 39.77  ? 502 PSF B N   1 
HETATM 6771 C  CA  . PSF P 2 .   ? 119.662 143.840 122.380 1.00 40.28  ? 502 PSF B CA  1 
HETATM 6772 C  CB  . PSF P 2 .   ? 121.060 144.428 122.380 1.00 39.89  ? 502 PSF B CB  1 
HETATM 6773 C  C   . PSF P 2 .   ? 118.697 144.751 123.154 1.00 46.89  ? 502 PSF B C   1 
HETATM 6774 O  OT1 . PSF P 2 .   ? 117.485 144.537 122.953 1.00 51.38  ? 502 PSF B OT1 1 
HETATM 6775 O  OT2 . PSF P 2 .   ? 119.185 145.614 123.905 1.00 46.07  ? 502 PSF B OT2 1 
HETATM 6776 C  C8  . PSF P 2 .   ? 125.736 149.429 132.288 1.00 48.50  ? 502 PSF B C8  1 
HETATM 6777 C  C9  . PSF P 2 .   ? 126.540 148.283 132.886 1.00 45.83  ? 502 PSF B C9  1 
HETATM 6778 C  C10 . PSF P 2 .   ? 127.743 148.755 133.688 1.00 41.28  ? 502 PSF B C10 1 
HETATM 6779 C  C16 . PSF P 2 .   ? 120.261 147.509 131.979 1.00 45.37  ? 502 PSF B C16 1 
HETATM 6780 C  C17 . PSF P 2 .   ? 120.968 147.662 133.318 1.00 40.50  ? 502 PSF B C17 1 
HETATM 6781 O  O2  . PSF Q 2 .   ? 135.188 146.645 120.787 1.00 46.83  ? 503 PSF B O2  1 
HETATM 6782 O  O1  . PSF Q 2 .   ? 133.882 145.227 119.216 1.00 53.22  ? 503 PSF B O1  1 
HETATM 6783 P  P   . PSF Q 2 .   ? 135.235 146.136 119.241 1.00 59.09  ? 503 PSF B P   1 
HETATM 6784 O  O4  . PSF Q 2 .   ? 135.041 147.368 118.420 1.00 58.56  ? 503 PSF B O4  1 
HETATM 6785 O  O3  . PSF Q 2 .   ? 136.427 145.258 119.038 1.00 56.70  ? 503 PSF B O3  1 
HETATM 6786 C  C2  . PSF Q 2 .   ? 135.646 145.791 121.805 1.00 44.22  ? 503 PSF B C2  1 
HETATM 6787 C  C3  . PSF Q 2 .   ? 135.948 146.645 123.015 1.00 47.19  ? 503 PSF B C3  1 
HETATM 6788 O  O11 . PSF Q 2 .   ? 134.855 146.590 123.925 1.00 51.00  ? 503 PSF B O11 1 
HETATM 6789 O  O12 . PSF Q 2 .   ? 135.040 144.575 124.859 1.00 58.07  ? 503 PSF B O12 1 
HETATM 6790 C  C1  . PSF Q 2 .   ? 134.889 145.762 124.961 1.00 52.88  ? 503 PSF B C1  1 
HETATM 6791 C  C4  . PSF Q 2 .   ? 136.095 148.092 122.623 1.00 48.48  ? 503 PSF B C4  1 
HETATM 6792 C  C5  . PSF Q 2 .   ? 137.116 149.720 123.943 1.00 51.82  ? 503 PSF B C5  1 
HETATM 6793 O  O51 . PSF Q 2 .   ? 137.707 150.150 122.988 1.00 52.08  ? 503 PSF B O51 1 
HETATM 6794 O  O52 . PSF Q 2 .   ? 136.130 148.847 123.829 1.00 52.54  ? 503 PSF B O52 1 
HETATM 6795 C  C6  . PSF Q 2 .   ? 137.385 150.071 125.377 1.00 49.49  ? 503 PSF B C6  1 
HETATM 6796 C  C7  . PSF Q 2 .   ? 136.122 150.232 126.200 1.00 52.36  ? 503 PSF B C7  1 
HETATM 6797 C  C13 . PSF Q 2 .   ? 134.703 146.511 126.249 1.00 47.05  ? 503 PSF B C13 1 
HETATM 6798 C  C14 . PSF Q 2 .   ? 134.819 145.592 127.466 1.00 45.09  ? 503 PSF B C14 1 
HETATM 6799 C  C15 . PSF Q 2 .   ? 134.353 146.256 128.752 1.00 49.28  ? 503 PSF B C15 1 
HETATM 6800 N  N   . PSF Q 2 .   ? 131.321 144.269 117.910 1.00 54.65  ? 503 PSF B N   1 
HETATM 6801 C  CA  . PSF Q 2 .   ? 131.498 144.801 119.260 1.00 52.44  ? 503 PSF B CA  1 
HETATM 6802 C  CB  . PSF Q 2 .   ? 132.608 145.832 119.215 1.00 50.96  ? 503 PSF B CB  1 
HETATM 6803 C  C   . PSF Q 2 .   ? 130.205 145.409 119.835 1.00 54.81  ? 503 PSF B C   1 
HETATM 6804 O  OT1 . PSF Q 2 .   ? 129.669 144.764 120.762 1.00 59.16  ? 503 PSF B OT1 1 
HETATM 6805 O  OT2 . PSF Q 2 .   ? 129.795 146.475 119.340 1.00 51.86  ? 503 PSF B OT2 1 
HETATM 6806 C  C8  . PSF Q 2 .   ? 136.420 150.359 127.688 1.00 54.71  ? 503 PSF B C8  1 
HETATM 6807 C  C9  . PSF Q 2 .   ? 137.150 149.146 128.247 1.00 53.76  ? 503 PSF B C9  1 
HETATM 6808 C  C10 . PSF Q 2 .   ? 137.321 149.199 129.757 1.00 51.01  ? 503 PSF B C10 1 
HETATM 6809 C  C16 . PSF Q 2 .   ? 134.752 145.468 129.989 1.00 54.16  ? 503 PSF B C16 1 
HETATM 6810 C  C17 . PSF Q 2 .   ? 133.985 145.906 131.227 1.00 50.59  ? 503 PSF B C17 1 
HETATM 6811 C  C1  . T7X R 3 .   ? 132.110 130.414 125.917 1.00 43.05  ? 504 T7X B C1  1 
HETATM 6812 O  O1  . T7X R 3 .   ? 132.711 131.673 126.089 1.00 49.82  ? 504 T7X B O1  1 
HETATM 6813 P  P1  . T7X R 3 .   ? 133.677 132.387 124.981 1.00 52.49  ? 504 T7X B P1  1 
HETATM 6814 C  C2  . T7X R 3 .   ? 130.967 130.350 126.920 1.00 41.01  ? 504 T7X B C2  1 
HETATM 6815 O  O2  . T7X R 3 .   ? 131.535 130.406 128.201 1.00 41.29  ? 504 T7X B O2  1 
HETATM 6816 C  C3  . T7X R 3 .   ? 130.150 129.075 126.780 1.00 47.55  ? 504 T7X B C3  1 
HETATM 6817 O  O3  . T7X R 3 .   ? 129.023 129.264 127.607 1.00 43.70  ? 504 T7X B O3  1 
HETATM 6818 C  C4  . T7X R 3 .   ? 129.738 128.787 125.343 1.00 52.44  ? 504 T7X B C4  1 
HETATM 6819 O  O4  . T7X R 3 .   ? 129.178 127.496 125.237 1.00 56.84  ? 504 T7X B O4  1 
HETATM 6820 C  C5  . T7X R 3 .   ? 130.948 128.814 124.426 1.00 49.52  ? 504 T7X B C5  1 
HETATM 6821 O  O5  . T7X R 3 .   ? 130.590 128.590 123.087 1.00 53.07  ? 504 T7X B O5  1 
HETATM 6822 C  C6  . T7X R 3 .   ? 131.625 130.173 124.494 1.00 44.78  ? 504 T7X B C6  1 
HETATM 6823 O  O6  . T7X R 3 .   ? 130.739 131.196 124.130 1.00 51.64  ? 504 T7X B O6  1 
HETATM 6824 C  C7  . T7X R 3 .   ? 134.787 132.593 127.344 1.00 42.19  ? 504 T7X B C7  1 
HETATM 6825 C  C8  . T7X R 3 .   ? 135.443 133.528 128.337 1.00 43.65  ? 504 T7X B C8  1 
HETATM 6826 C  C9  . T7X R 3 .   ? 136.456 132.896 129.256 1.00 43.76  ? 504 T7X B C9  1 
HETATM 6827 C  C10 . T7X R 3 .   ? 135.473 135.777 127.583 1.00 52.85  ? 504 T7X B C10 1 
HETATM 6828 C  C11 . T7X R 3 .   ? 138.338 133.783 130.307 1.00 47.75  ? 504 T7X B C11 1 
HETATM 6829 O  O11 . T7X R 3 .   ? 132.906 133.351 124.143 1.00 45.27  ? 504 T7X B O11 1 
HETATM 6830 C  C12 . T7X R 3 .   ? 136.130 136.699 126.600 1.00 45.23  ? 504 T7X B C12 1 
HETATM 6831 O  O12 . T7X R 3 .   ? 134.578 131.380 124.335 1.00 54.60  ? 504 T7X B O12 1 
HETATM 6832 C  C13 . T7X R 3 .   ? 137.640 136.733 126.700 1.00 42.59  ? 504 T7X B C13 1 
HETATM 6833 O  O13 . T7X R 3 .   ? 134.517 133.216 126.116 1.00 43.87  ? 504 T7X B O13 1 
HETATM 6834 C  C14 . T7X R 3 .   ? 138.076 137.124 128.107 1.00 43.96  ? 504 T7X B C14 1 
HETATM 6835 C  C15 . T7X R 3 .   ? 138.684 138.485 128.156 1.00 47.98  ? 504 T7X B C15 1 
HETATM 6836 C  C16 . T7X R 3 .   ? 139.825 138.853 128.728 1.00 49.92  ? 504 T7X B C16 1 
HETATM 6837 O  O16 . T7X R 3 .   ? 136.095 134.606 127.659 1.00 50.93  ? 504 T7X B O16 1 
HETATM 6838 C  C17 . T7X R 3 .   ? 140.390 140.240 128.762 1.00 53.51  ? 504 T7X B C17 1 
HETATM 6839 O  O17 . T7X R 3 .   ? 134.493 136.049 128.224 1.00 54.62  ? 504 T7X B O17 1 
HETATM 6840 C  C18 . T7X R 3 .   ? 139.492 141.089 129.615 1.00 53.30  ? 504 T7X B C18 1 
HETATM 6841 O  O18 . T7X R 3 .   ? 137.054 133.914 130.037 1.00 45.69  ? 504 T7X B O18 1 
HETATM 6842 C  C19 . T7X R 3 .   ? 138.462 141.826 129.203 1.00 52.88  ? 504 T7X B C19 1 
HETATM 6843 O  O19 . T7X R 3 .   ? 138.934 132.759 130.108 1.00 53.15  ? 504 T7X B O19 1 
HETATM 6844 C  C20 . T7X R 3 .   ? 137.540 142.676 130.029 1.00 52.62  ? 504 T7X B C20 1 
HETATM 6845 C  C21 . T7X R 3 .   ? 136.322 141.883 130.395 1.00 53.63  ? 504 T7X B C21 1 
HETATM 6846 C  C22 . T7X R 3 .   ? 136.193 141.181 131.514 1.00 52.85  ? 504 T7X B C22 1 
HETATM 6847 C  C23 . T7X R 3 .   ? 134.989 140.375 131.900 1.00 50.81  ? 504 T7X B C23 1 
HETATM 6848 C  C24 . T7X R 3 .   ? 135.389 138.987 132.312 1.00 53.55  ? 504 T7X B C24 1 
HETATM 6849 C  C25 . T7X R 3 .   ? 136.620 138.596 132.623 1.00 51.41  ? 504 T7X B C25 1 
HETATM 6850 C  C26 . T7X R 3 .   ? 137.001 137.210 133.033 1.00 47.15  ? 504 T7X B C26 1 
HETATM 6851 C  C27 . T7X R 3 .   ? 137.352 137.117 134.517 1.00 43.69  ? 504 T7X B C27 1 
HETATM 6852 C  C31 . T7X R 3 .   ? 138.921 135.040 130.866 1.00 47.17  ? 504 T7X B C31 1 
HETATM 6853 C  C32 . T7X R 3 .   ? 140.352 134.927 131.352 1.00 47.13  ? 504 T7X B C32 1 
HETATM 6854 C  C33 . T7X R 3 .   ? 141.070 136.254 131.174 1.00 46.20  ? 504 T7X B C33 1 
HETATM 6855 C  C34 . T7X R 3 .   ? 141.736 136.766 132.439 1.00 45.16  ? 504 T7X B C34 1 
HETATM 6856 C  C35 . T7X R 3 .   ? 143.072 136.095 132.703 1.00 48.15  ? 504 T7X B C35 1 
HETATM 6857 C  C36 . T7X R 3 .   ? 143.926 136.836 133.722 1.00 48.12  ? 504 T7X B C36 1 
HETATM 6858 C  C37 . T7X R 3 .   ? 143.318 136.874 135.116 1.00 48.02  ? 504 T7X B C37 1 
HETATM 6859 C  C38 . T7X R 3 .   ? 144.281 137.425 136.158 1.00 47.97  ? 504 T7X B C38 1 
HETATM 6860 C  C28 . T7X R 3 .   ? 136.137 137.194 135.431 1.00 41.75  ? 504 T7X B C28 1 
HETATM 6861 C  C1  . LBN S 4 .   ? 123.167 130.610 163.083 1.00 62.96  ? 505 LBN B C1  1 
HETATM 6862 N  N1  . LBN S 4 .   ? 126.576 129.901 168.800 1.00 67.58  ? 505 LBN B N1  1 
HETATM 6863 P  P1  . LBN S 4 .   ? 124.701 130.818 165.199 1.00 87.77  ? 505 LBN B P1  1 
HETATM 6864 C  C2  . LBN S 4 .   ? 123.229 130.646 161.566 1.00 63.41  ? 505 LBN B C2  1 
HETATM 6865 C  C3  . LBN S 4 .   ? 124.441 129.941 161.005 1.00 56.98  ? 505 LBN B C3  1 
HETATM 6866 C  C4  . LBN S 4 .   ? 123.496 128.402 151.807 1.00 59.91  ? 505 LBN B C4  1 
HETATM 6867 C  C5  . LBN S 4 .   ? 124.922 124.511 152.028 1.00 58.53  ? 505 LBN B C5  1 
HETATM 6868 C  C6  . LBN S 4 .   ? 126.645 130.632 167.484 1.00 61.76  ? 505 LBN B C6  1 
HETATM 6869 O  O1  . LBN S 4 .   ? 124.480 130.665 163.590 1.00 70.48  ? 505 LBN B O1  1 
HETATM 6870 C  C7  . LBN S 4 .   ? 122.894 128.056 150.455 1.00 54.74  ? 505 LBN B C7  1 
HETATM 6871 C  C8  . LBN S 4 .   ? 125.545 123.467 151.159 1.00 58.56  ? 505 LBN B C8  1 
HETATM 6872 C  C9  . LBN S 4 .   ? 126.926 129.820 166.240 1.00 59.97  ? 505 LBN B C9  1 
HETATM 6873 O  O2  . LBN S 4 .   ? 126.264 130.296 165.089 1.00 69.24  ? 505 LBN B O2  1 
HETATM 6874 C  C10 . LBN S 4 .   ? 123.436 128.967 149.369 1.00 59.35  ? 505 LBN B C10 1 
HETATM 6875 C  C11 . LBN S 4 .   ? 125.386 123.749 149.668 1.00 61.88  ? 505 LBN B C11 1 
HETATM 6876 C  C12 . LBN S 4 .   ? 125.670 128.719 168.737 1.00 62.35  ? 505 LBN B C12 1 
HETATM 6877 O  O3  . LBN S 4 .   ? 124.676 132.263 165.608 1.00 65.42  ? 505 LBN B O3  1 
HETATM 6878 C  C13 . LBN S 4 .   ? 123.101 128.527 147.953 1.00 57.42  ? 505 LBN B C13 1 
HETATM 6879 C  C14 . LBN S 4 .   ? 125.547 122.493 148.822 1.00 61.69  ? 505 LBN B C14 1 
HETATM 6880 C  C15 . LBN S 4 .   ? 126.118 130.803 169.894 1.00 62.51  ? 505 LBN B C15 1 
HETATM 6881 O  O4  . LBN S 4 .   ? 123.853 129.829 165.936 1.00 64.79  ? 505 LBN B O4  1 
HETATM 6882 C  C16 . LBN S 4 .   ? 123.764 127.220 147.561 1.00 59.58  ? 505 LBN B C16 1 
HETATM 6883 C  C17 . LBN S 4 .   ? 126.989 122.198 148.438 1.00 58.98  ? 505 LBN B C17 1 
HETATM 6884 C  C18 . LBN S 4 .   ? 127.957 129.428 169.107 1.00 65.29  ? 505 LBN B C18 1 
HETATM 6885 C  C19 . LBN S 4 .   ? 125.261 127.209 147.817 1.00 62.62  ? 505 LBN B C19 1 
HETATM 6886 C  C20 . LBN S 4 .   ? 127.602 121.042 149.215 1.00 57.30  ? 505 LBN B C20 1 
HETATM 6887 C  C21 . LBN S 4 .   ? 126.003 128.286 147.043 1.00 61.25  ? 505 LBN B C21 1 
HETATM 6888 C  C22 . LBN S 4 .   ? 129.009 120.690 148.756 1.00 59.88  ? 505 LBN B C22 1 
HETATM 6889 C  C23 . LBN S 4 .   ? 129.092 119.380 147.983 1.00 59.05  ? 505 LBN B C23 1 
HETATM 6890 C  C24 . LBN S 4 .   ? 130.495 118.794 147.979 1.00 56.54  ? 505 LBN B C24 1 
HETATM 6891 C  C25 . LBN S 4 .   ? 126.295 130.402 159.658 1.00 64.11  ? 505 LBN B C25 1 
HETATM 6892 O  O5  . LBN S 4 .   ? 125.079 130.758 160.035 1.00 61.05  ? 505 LBN B O5  1 
HETATM 6893 C  C26 . LBN S 4 .   ? 126.543 130.738 158.219 1.00 60.40  ? 505 LBN B C26 1 
HETATM 6894 O  O6  . LBN S 4 .   ? 127.084 129.863 160.394 1.00 64.72  ? 505 LBN B O6  1 
HETATM 6895 C  C27 . LBN S 4 .   ? 125.325 131.280 157.495 1.00 57.61  ? 505 LBN B C27 1 
HETATM 6896 C  C28 . LBN S 4 .   ? 125.651 131.592 156.043 1.00 60.82  ? 505 LBN B C28 1 
HETATM 6897 C  C29 . LBN S 4 .   ? 124.542 132.337 155.314 1.00 62.74  ? 505 LBN B C29 1 
HETATM 6898 C  C30 . LBN S 4 .   ? 124.482 131.991 153.834 1.00 62.41  ? 505 LBN B C30 1 
HETATM 6899 C  C31 . LBN S 4 .   ? 124.532 130.490 153.584 1.00 62.55  ? 505 LBN B C31 1 
HETATM 6900 C  C32 . LBN S 4 .   ? 123.231 129.780 153.926 1.00 59.93  ? 505 LBN B C32 1 
HETATM 6901 C  C33 . LBN S 4 .   ? 122.548 129.182 152.703 1.00 62.58  ? 505 LBN B C33 1 
HETATM 6902 C  C34 . LBN S 4 .   ? 121.889 128.789 160.792 1.00 67.29  ? 505 LBN B C34 1 
HETATM 6903 O  O7  . LBN S 4 .   ? 122.048 130.101 160.960 1.00 67.94  ? 505 LBN B O7  1 
HETATM 6904 C  C35 . LBN S 4 .   ? 121.630 128.453 159.348 1.00 62.81  ? 505 LBN B C35 1 
HETATM 6905 O  O8  . LBN S 4 .   ? 121.935 127.990 161.691 1.00 64.38  ? 505 LBN B O8  1 
HETATM 6906 C  C36 . LBN S 4 .   ? 122.216 127.126 158.889 1.00 61.37  ? 505 LBN B C36 1 
HETATM 6907 C  C37 . LBN S 4 .   ? 123.734 127.080 159.024 1.00 61.52  ? 505 LBN B C37 1 
HETATM 6908 C  C38 . LBN S 4 .   ? 124.395 126.083 158.083 1.00 60.02  ? 505 LBN B C38 1 
HETATM 6909 C  C39 . LBN S 4 .   ? 124.324 126.501 156.621 1.00 62.01  ? 505 LBN B C39 1 
HETATM 6910 C  C40 . LBN S 4 .   ? 124.669 125.372 155.658 1.00 60.05  ? 505 LBN B C40 1 
HETATM 6911 C  C41 . LBN S 4 .   ? 124.667 125.818 154.196 1.00 59.56  ? 505 LBN B C41 1 
HETATM 6912 C  C42 . LBN S 4 .   ? 125.258 124.788 153.286 1.00 58.80  ? 505 LBN B C42 1 
HETATM 6913 C  C1  . LBN T 4 .   ? 114.668 151.879 146.528 1.00 90.06  ? 506 LBN B C1  1 
HETATM 6914 N  N1  . LBN T 4 .   ? 110.675 153.581 150.875 1.00 92.76  ? 506 LBN B N1  1 
HETATM 6915 P  P1  . LBN T 4 .   ? 112.399 150.725 147.149 1.00 105.66 ? 506 LBN B P1  1 
HETATM 6916 C  C2  . LBN T 4 .   ? 115.840 151.750 145.565 1.00 89.53  ? 506 LBN B C2  1 
HETATM 6917 C  C3  . LBN T 4 .   ? 117.197 151.739 146.228 1.00 91.21  ? 506 LBN B C3  1 
HETATM 6918 C  C6  . LBN T 4 .   ? 111.477 152.607 150.049 1.00 92.23  ? 506 LBN B C6  1 
HETATM 6919 O  O1  . LBN T 4 .   ? 113.565 151.125 146.077 1.00 94.61  ? 506 LBN B O1  1 
HETATM 6920 C  C9  . LBN T 4 .   ? 111.113 152.465 148.588 1.00 89.97  ? 506 LBN B C9  1 
HETATM 6921 O  O2  . LBN T 4 .   ? 112.229 152.247 147.755 1.00 95.00  ? 506 LBN B O2  1 
HETATM 6922 C  C12 . LBN T 4 .   ? 110.888 154.992 150.449 1.00 91.03  ? 506 LBN B C12 1 
HETATM 6923 O  O3  . LBN T 4 .   ? 112.932 149.840 148.239 1.00 92.34  ? 506 LBN B O3  1 
HETATM 6924 C  C15 . LBN T 4 .   ? 110.996 153.459 152.324 1.00 88.27  ? 506 LBN B C15 1 
HETATM 6925 O  O4  . LBN T 4 .   ? 111.150 150.327 146.429 1.00 90.03  ? 506 LBN B O4  1 
HETATM 6926 C  C18 . LBN T 4 .   ? 109.239 153.241 150.672 1.00 91.31  ? 506 LBN B C18 1 
HETATM 6927 C  C25 . LBN T 4 .   ? 119.059 152.946 145.429 1.00 91.98  ? 506 LBN B C25 1 
HETATM 6928 O  O5  . LBN T 4 .   ? 117.861 152.975 145.996 1.00 93.91  ? 506 LBN B O5  1 
HETATM 6929 C  C26 . LBN T 4 .   ? 118.995 153.351 143.985 1.00 90.82  ? 506 LBN B C26 1 
HETATM 6930 O  O6  . LBN T 4 .   ? 120.065 152.635 146.015 1.00 90.47  ? 506 LBN B O6  1 
HETATM 6931 C  C27 . LBN T 4 .   ? 120.350 153.491 143.309 1.00 92.28  ? 506 LBN B C27 1 
HETATM 6932 C  C28 . LBN T 4 .   ? 120.314 154.518 142.183 1.00 93.26  ? 506 LBN B C28 1 
HETATM 6933 C  C29 . LBN T 4 .   ? 119.270 154.215 141.116 1.00 91.74  ? 506 LBN B C29 1 
HETATM 6934 C  C30 . LBN T 4 .   ? 119.579 152.958 140.314 1.00 89.58  ? 506 LBN B C30 1 
HETATM 6935 C  C34 . LBN T 4 .   ? 115.613 150.659 143.449 1.00 93.72  ? 506 LBN B C34 1 
HETATM 6936 O  O7  . LBN T 4 .   ? 115.741 150.562 144.773 1.00 90.74  ? 506 LBN B O7  1 
HETATM 6937 C  C35 . LBN T 4 .   ? 116.944 150.524 142.758 1.00 89.07  ? 506 LBN B C35 1 
HETATM 6938 O  O8  . LBN T 4 .   ? 114.554 150.826 142.897 1.00 93.48  ? 506 LBN B O8  1 
HETATM 6939 C  C36 . LBN T 4 .   ? 116.885 150.630 141.242 1.00 87.72  ? 506 LBN B C36 1 
HETATM 6940 C  C37 . LBN T 4 .   ? 116.226 149.420 140.591 1.00 87.30  ? 506 LBN B C37 1 
HETATM 6941 C  C38 . LBN T 4 .   ? 117.190 148.595 139.749 1.00 87.58  ? 506 LBN B C38 1 
HETATM 6942 C  C39 . LBN T 4 .   ? 118.071 149.436 138.836 1.00 90.17  ? 506 LBN B C39 1 
HETATM 6943 C  C40 . LBN T 4 .   ? 118.869 148.609 137.837 1.00 86.71  ? 506 LBN B C40 1 
HETATM 6944 C  C41 . LBN T 4 .   ? 119.907 147.700 138.496 1.00 86.08  ? 506 LBN B C41 1 
HETATM 6945 C  C1  . D12 U 5 .   ? 120.855 155.402 154.005 1.00 75.53  ? 507 D12 B C1  1 
HETATM 6946 C  C2  . D12 U 5 .   ? 120.550 155.099 152.544 1.00 78.74  ? 507 D12 B C2  1 
HETATM 6947 C  C3  . D12 U 5 .   ? 121.680 154.351 151.849 1.00 77.18  ? 507 D12 B C3  1 
HETATM 6948 C  C4  . D12 U 5 .   ? 121.389 154.055 150.384 1.00 76.72  ? 507 D12 B C4  1 
HETATM 6949 C  C5  . D12 U 5 .   ? 122.625 153.626 149.606 1.00 74.09  ? 507 D12 B C5  1 
HETATM 6950 C  C6  . D12 U 5 .   ? 122.374 153.513 148.109 1.00 75.10  ? 507 D12 B C6  1 
HETATM 6951 C  C7  . D12 U 5 .   ? 123.596 153.053 147.325 1.00 75.58  ? 507 D12 B C7  1 
HETATM 6952 C  C8  . D12 U 5 .   ? 123.374 153.071 145.819 1.00 77.46  ? 507 D12 B C8  1 
HETATM 6953 C  C9  . D12 U 5 .   ? 124.437 152.314 145.035 1.00 77.49  ? 507 D12 B C9  1 
HETATM 6954 C  C10 . D12 U 5 .   ? 124.048 152.093 143.580 1.00 74.90  ? 507 D12 B C10 1 
HETATM 6955 C  C11 . D12 U 5 .   ? 125.051 151.251 142.803 1.00 74.92  ? 507 D12 B C11 1 
HETATM 6956 C  C12 . D12 U 5 .   ? 124.655 151.068 141.345 1.00 76.70  ? 507 D12 B C12 1 
HETATM 6957 C  C01 . C14 V 6 .   ? 123.077 143.059 138.217 1.00 53.97  ? 508 C14 B C01 1 
HETATM 6958 C  C02 . C14 V 6 .   ? 123.438 143.861 139.457 1.00 56.18  ? 508 C14 B C02 1 
HETATM 6959 C  C03 . C14 V 6 .   ? 124.032 142.998 140.561 1.00 59.36  ? 508 C14 B C03 1 
HETATM 6960 C  C04 . C14 V 6 .   ? 124.491 143.809 141.764 1.00 56.17  ? 508 C14 B C04 1 
HETATM 6961 C  C05 . C14 V 6 .   ? 124.490 143.026 143.069 1.00 56.22  ? 508 C14 B C05 1 
HETATM 6962 C  C06 . C14 V 6 .   ? 123.948 143.843 144.233 1.00 58.15  ? 508 C14 B C06 1 
HETATM 6963 C  C07 . C14 V 6 .   ? 124.607 143.522 145.566 1.00 59.65  ? 508 C14 B C07 1 
HETATM 6964 C  C08 . C14 V 6 .   ? 124.833 144.763 146.418 1.00 61.01  ? 508 C14 B C08 1 
HETATM 6965 C  C09 . C14 V 6 .   ? 125.413 144.463 147.794 1.00 58.99  ? 508 C14 B C09 1 
HETATM 6966 C  C10 . C14 V 6 .   ? 125.627 145.714 148.634 1.00 55.02  ? 508 C14 B C10 1 
HETATM 6967 C  C11 . C14 V 6 .   ? 126.155 145.412 150.029 1.00 57.98  ? 508 C14 B C11 1 
HETATM 6968 C  C12 . C14 V 6 .   ? 126.599 146.656 150.788 1.00 57.70  ? 508 C14 B C12 1 
HETATM 6969 C  C13 . C14 V 6 .   ? 127.117 146.353 152.188 1.00 58.08  ? 508 C14 B C13 1 
HETATM 6970 C  C14 . C14 V 6 .   ? 127.455 147.610 152.975 1.00 58.60  ? 508 C14 B C14 1 
HETATM 6971 C  C1  . LBN W 4 .   ? 102.898 131.439 124.392 1.00 46.57  ? 509 LBN B C1  1 
HETATM 6972 N  N1  . LBN W 4 .   ? 106.740 129.402 120.600 1.00 48.18  ? 509 LBN B N1  1 
HETATM 6973 P  P1  . LBN W 4 .   ? 103.115 129.282 122.941 1.00 71.45  ? 509 LBN B P1  1 
HETATM 6974 C  C2  . LBN W 4 .   ? 103.390 131.028 125.772 1.00 46.15  ? 509 LBN B C2  1 
HETATM 6975 C  C3  . LBN W 4 .   ? 103.986 132.143 126.600 1.00 48.77  ? 509 LBN B C3  1 
HETATM 6976 C  C4  . LBN W 4 .   ? 109.276 135.878 133.566 1.00 39.21  ? 509 LBN B C4  1 
HETATM 6977 C  C5  . LBN W 4 .   ? 96.331  132.182 136.289 1.00 54.04  ? 509 LBN B C5  1 
HETATM 6978 C  C6  . LBN W 4 .   ? 105.878 130.626 120.711 1.00 47.67  ? 509 LBN B C6  1 
HETATM 6979 O  O1  . LBN W 4 .   ? 102.232 130.360 123.783 1.00 52.58  ? 509 LBN B O1  1 
HETATM 6980 C  C7  . LBN W 4 .   ? 108.429 137.127 133.754 1.00 41.13  ? 509 LBN B C7  1 
HETATM 6981 C  C8  . LBN W 4 .   ? 95.443  132.930 137.231 1.00 48.89  ? 509 LBN B C8  1 
HETATM 6982 C  C9  . LBN W 4 .   ? 104.412 130.425 121.003 1.00 52.52  ? 509 LBN B C9  1 
HETATM 6983 O  O2  . LBN W 4 .   ? 104.131 130.443 122.380 1.00 52.04  ? 509 LBN B O2  1 
HETATM 6984 C  C10 . LBN W 4 .   ? 109.222 138.419 133.665 1.00 42.36  ? 509 LBN B C10 1 
HETATM 6985 C  C11 . LBN W 4 .   ? 96.093  133.040 138.611 1.00 49.31  ? 509 LBN B C11 1 
HETATM 6986 C  C12 . LBN W 4 .   ? 106.391 128.354 121.596 1.00 45.13  ? 509 LBN B C12 1 
HETATM 6987 O  O3  . LBN W 4 .   ? 103.883 128.367 123.844 1.00 56.61  ? 509 LBN B O3  1 
HETATM 6988 C  C13 . LBN W 4 .   ? 108.612 139.538 134.496 1.00 44.00  ? 509 LBN B C13 1 
HETATM 6989 C  C14 . LBN W 4 .   ? 95.095  133.181 139.753 1.00 51.05  ? 509 LBN B C14 1 
HETATM 6990 C  C15 . LBN W 4 .   ? 108.171 129.758 120.761 1.00 48.29  ? 509 LBN B C15 1 
HETATM 6991 O  O4  . LBN W 4 .   ? 102.312 128.709 121.819 1.00 52.15  ? 509 LBN B O4  1 
HETATM 6992 C  C16 . LBN W 4 .   ? 109.463 140.795 134.540 1.00 39.31  ? 509 LBN B C16 1 
HETATM 6993 C  C17 . LBN W 4 .   ? 95.765  133.446 141.095 1.00 50.63  ? 509 LBN B C17 1 
HETATM 6994 C  C18 . LBN W 4 .   ? 106.527 128.835 119.243 1.00 48.11  ? 509 LBN B C18 1 
HETATM 6995 C  C19 . LBN W 4 .   ? 108.778 141.933 135.277 1.00 41.17  ? 509 LBN B C19 1 
HETATM 6996 C  C20 . LBN W 4 .   ? 94.849  134.086 142.132 1.00 51.01  ? 509 LBN B C20 1 
HETATM 6997 C  C21 . LBN W 4 .   ? 109.504 143.257 135.121 1.00 45.74  ? 509 LBN B C21 1 
HETATM 6998 C  C22 . LBN W 4 .   ? 95.371  133.959 143.557 1.00 54.83  ? 509 LBN B C22 1 
HETATM 6999 C  C23 . LBN W 4 .   ? 96.893  133.988 143.649 1.00 53.14  ? 509 LBN B C23 1 
HETATM 7000 C  C24 . LBN W 4 .   ? 97.428  133.400 144.948 1.00 47.63  ? 509 LBN B C24 1 
HETATM 7001 C  C25 . LBN W 4 .   ? 105.211 130.895 128.174 1.00 48.02  ? 509 LBN B C25 1 
HETATM 7002 O  O5  . LBN W 4 .   ? 104.177 131.679 127.925 1.00 51.01  ? 509 LBN B O5  1 
HETATM 7003 C  C26 . LBN W 4 .   ? 106.403 131.679 128.619 1.00 47.30  ? 509 LBN B C26 1 
HETATM 7004 O  O6  . LBN W 4 .   ? 105.183 129.699 128.059 1.00 50.80  ? 509 LBN B O6  1 
HETATM 7005 C  C27 . LBN W 4 .   ? 107.277 130.942 129.619 1.00 48.82  ? 509 LBN B C27 1 
HETATM 7006 C  C28 . LBN W 4 .   ? 106.605 130.815 130.976 1.00 44.83  ? 509 LBN B C28 1 
HETATM 7007 C  C29 . LBN W 4 .   ? 107.523 130.201 132.023 1.00 47.39  ? 509 LBN B C29 1 
HETATM 7008 C  C30 . LBN W 4 .   ? 108.665 131.118 132.437 1.00 42.89  ? 509 LBN B C30 1 
HETATM 7009 C  C31 . LBN W 4 .   ? 108.251 132.154 133.471 1.00 48.69  ? 509 LBN B C31 1 
HETATM 7010 C  C32 . LBN W 4 .   ? 109.217 133.324 133.576 1.00 44.57  ? 509 LBN B C32 1 
HETATM 7011 C  C33 . LBN W 4 .   ? 108.531 134.620 133.984 1.00 45.98  ? 509 LBN B C33 1 
HETATM 7012 C  C34 . LBN W 4 .   ? 101.222 130.904 126.874 1.00 49.33  ? 509 LBN B C34 1 
HETATM 7013 O  O7  . LBN W 4 .   ? 102.393 130.355 126.556 1.00 47.65  ? 509 LBN B O7  1 
HETATM 7014 C  C35 . LBN W 4 .   ? 100.342 129.932 127.604 1.00 49.06  ? 509 LBN B C35 1 
HETATM 7015 O  O8  . LBN W 4 .   ? 100.901 132.031 126.619 1.00 54.84  ? 509 LBN B O8  1 
HETATM 7016 C  C36 . LBN W 4 .   ? 99.222  130.595 128.384 1.00 48.87  ? 509 LBN B C36 1 
HETATM 7017 C  C37 . LBN W 4 .   ? 99.606  130.820 129.840 1.00 43.41  ? 509 LBN B C37 1 
HETATM 7018 C  C38 . LBN W 4 .   ? 98.453  131.342 130.685 1.00 41.67  ? 509 LBN B C38 1 
HETATM 7019 C  C39 . LBN W 4 .   ? 98.738  131.242 132.175 1.00 44.73  ? 509 LBN B C39 1 
HETATM 7020 C  C40 . LBN W 4 .   ? 97.760  132.013 133.046 1.00 45.32  ? 509 LBN B C40 1 
HETATM 7021 C  C41 . LBN W 4 .   ? 98.115  131.874 134.526 1.00 50.30  ? 509 LBN B C41 1 
HETATM 7022 C  C42 . LBN W 4 .   ? 97.238  132.668 135.442 1.00 53.12  ? 509 LBN B C42 1 
HETATM 7023 CA CA  . CA  X 7 .   ? 105.113 151.923 146.644 1.00 68.17  ? 510 CA  B CA  1 
HETATM 7024 C  C1  . LBN Y 4 .   ? 129.889 144.014 155.648 1.00 62.68  ? 511 LBN B C1  1 
HETATM 7025 N  N1  . LBN Y 4 .   ? 129.560 139.164 159.098 1.00 62.74  ? 511 LBN B N1  1 
HETATM 7026 P  P1  . LBN Y 4 .   ? 129.931 143.774 158.249 1.00 87.06  ? 511 LBN B P1  1 
HETATM 7027 C  C2  . LBN Y 4 .   ? 128.605 143.901 154.842 1.00 65.30  ? 511 LBN B C2  1 
HETATM 7028 C  C3  . LBN Y 4 .   ? 128.710 142.986 153.647 1.00 66.78  ? 511 LBN B C3  1 
HETATM 7029 C  C4  . LBN Y 4 .   ? 128.752 140.370 143.779 1.00 64.58  ? 511 LBN B C4  1 
HETATM 7030 C  C5  . LBN Y 4 .   ? 122.380 141.346 148.852 1.00 62.72  ? 511 LBN B C5  1 
HETATM 7031 C  C6  . LBN Y 4 .   ? 130.814 139.986 158.997 1.00 65.34  ? 511 LBN B C6  1 
HETATM 7032 O  O1  . LBN Y 4 .   ? 129.855 143.138 156.749 1.00 65.61  ? 511 LBN B O1  1 
HETATM 7033 C  C7  . LBN Y 4 .   ? 128.710 141.274 142.552 1.00 64.87  ? 511 LBN B C7  1 
HETATM 7034 C  C8  . LBN Y 4 .   ? 121.424 140.219 149.084 1.00 61.81  ? 511 LBN B C8  1 
HETATM 7035 C  C9  . LBN Y 4 .   ? 130.741 141.296 158.251 1.00 64.77  ? 511 LBN B C9  1 
HETATM 7036 O  O2  . LBN Y 4 .   ? 130.035 142.290 158.955 1.00 69.74  ? 511 LBN B O2  1 
HETATM 7037 C  C10 . LBN Y 4 .   ? 129.832 140.977 141.564 1.00 66.63  ? 511 LBN B C10 1 
HETATM 7038 C  C11 . LBN Y 4 .   ? 120.354 140.108 147.998 1.00 63.66  ? 511 LBN B C11 1 
HETATM 7039 C  C12 . LBN Y 4 .   ? 129.865 137.723 159.306 1.00 61.57  ? 511 LBN B C12 1 
HETATM 7040 O  O3  . LBN Y 4 .   ? 131.229 144.498 158.459 1.00 71.17  ? 511 LBN B O3  1 
HETATM 7041 C  C13 . LBN Y 4 .   ? 129.572 141.482 140.150 1.00 64.12  ? 511 LBN B C13 1 
HETATM 7042 C  C14 . LBN Y 4 .   ? 120.722 139.157 146.865 1.00 61.76  ? 511 LBN B C14 1 
HETATM 7043 C  C15 . LBN Y 4 .   ? 128.710 139.314 157.886 1.00 59.37  ? 511 LBN B C15 1 
HETATM 7044 O  O4  . LBN Y 4 .   ? 128.643 144.440 158.621 1.00 67.91  ? 511 LBN B O4  1 
HETATM 7045 C  C16 . LBN Y 4 .   ? 128.294 140.938 139.525 1.00 62.79  ? 511 LBN B C16 1 
HETATM 7046 C  C17 . LBN Y 4 .   ? 121.787 139.704 145.923 1.00 64.97  ? 511 LBN B C17 1 
HETATM 7047 C  C18 . LBN Y 4 .   ? 128.810 139.657 160.284 1.00 63.36  ? 511 LBN B C18 1 
HETATM 7048 C  C19 . LBN Y 4 .   ? 128.222 141.151 138.019 1.00 61.32  ? 511 LBN B C19 1 
HETATM 7049 C  C20 . LBN Y 4 .   ? 122.380 138.660 144.986 1.00 62.46  ? 511 LBN B C20 1 
HETATM 7050 C  C21 . LBN Y 4 .   ? 128.710 142.522 137.576 1.00 61.37  ? 511 LBN B C21 1 
HETATM 7051 C  C22 . LBN Y 4 .   ? 122.443 137.264 145.590 1.00 63.01  ? 511 LBN B C22 1 
HETATM 7052 C  C23 . LBN Y 4 .   ? 123.579 136.419 145.036 1.00 59.09  ? 511 LBN B C23 1 
HETATM 7053 C  C24 . LBN Y 4 .   ? 124.907 136.713 145.711 1.00 57.54  ? 511 LBN B C24 1 
HETATM 7054 C  C25 . LBN Y 4 .   ? 130.252 142.634 151.885 1.00 66.54  ? 511 LBN B C25 1 
HETATM 7055 O  O5  . LBN Y 4 .   ? 129.751 143.452 152.799 1.00 68.26  ? 511 LBN B O5  1 
HETATM 7056 C  C26 . LBN Y 4 .   ? 129.178 142.023 151.033 1.00 63.20  ? 511 LBN B C26 1 
HETATM 7057 O  O6  . LBN Y 4 .   ? 131.433 142.425 151.764 1.00 66.19  ? 511 LBN B O6  1 
HETATM 7058 C  C27 . LBN Y 4 .   ? 129.709 141.313 149.798 1.00 63.21  ? 511 LBN B C27 1 
HETATM 7059 C  C28 . LBN Y 4 .   ? 128.605 141.013 148.794 1.00 67.43  ? 511 LBN B C28 1 
HETATM 7060 C  C29 . LBN Y 4 .   ? 127.528 140.076 149.324 1.00 67.65  ? 511 LBN B C29 1 
HETATM 7061 C  C30 . LBN Y 4 .   ? 126.947 139.150 148.260 1.00 65.51  ? 511 LBN B C30 1 
HETATM 7062 C  C31 . LBN Y 4 .   ? 126.580 139.848 146.956 1.00 64.77  ? 511 LBN B C31 1 
HETATM 7063 C  C32 . LBN Y 4 .   ? 127.486 139.469 145.791 1.00 64.39  ? 511 LBN B C32 1 
HETATM 7064 C  C33 . LBN Y 4 .   ? 127.557 140.537 144.707 1.00 67.29  ? 511 LBN B C33 1 
HETATM 7065 C  C34 . LBN Y 4 .   ? 126.724 144.328 156.246 1.00 69.42  ? 511 LBN B C34 1 
HETATM 7066 O  O7  . LBN Y 4 .   ? 127.517 143.440 155.647 1.00 68.59  ? 511 LBN B O7  1 
HETATM 7067 C  C35 . LBN Y 4 .   ? 125.596 143.646 156.966 1.00 64.71  ? 511 LBN B C35 1 
HETATM 7068 O  O8  . LBN Y 4 .   ? 126.900 145.519 156.206 1.00 68.47  ? 511 LBN B O8  1 
HETATM 7069 C  C36 . LBN Y 4 .   ? 124.834 142.673 156.085 1.00 63.99  ? 511 LBN B C36 1 
HETATM 7070 C  C37 . LBN Y 4 .   ? 124.391 143.333 154.788 1.00 64.21  ? 511 LBN B C37 1 
HETATM 7071 C  C38 . LBN Y 4 .   ? 125.031 142.706 153.560 1.00 60.42  ? 511 LBN B C38 1 
HETATM 7072 C  C39 . LBN Y 4 .   ? 124.490 141.318 153.256 1.00 63.88  ? 511 LBN B C39 1 
HETATM 7073 C  C40 . LBN Y 4 .   ? 124.272 141.095 151.768 1.00 59.85  ? 511 LBN B C40 1 
HETATM 7074 C  C41 . LBN Y 4 .   ? 123.034 141.824 151.252 1.00 58.16  ? 511 LBN B C41 1 
HETATM 7075 C  C42 . LBN Y 4 .   ? 123.062 142.024 149.771 1.00 64.38  ? 511 LBN B C42 1 
HETATM 7076 N  N   . SER Z 8 .   ? 107.223 147.511 148.391 1.00 73.08  ? 512 SER B N   1 
HETATM 7077 C  CA  . SER Z 8 .   ? 108.223 148.390 147.798 1.00 77.38  ? 512 SER B CA  1 
HETATM 7078 C  C   . SER Z 8 .   ? 107.728 149.834 147.756 1.00 78.85  ? 512 SER B C   1 
HETATM 7079 O  O   . SER Z 8 .   ? 106.718 150.142 147.123 1.00 78.39  ? 512 SER B O   1 
HETATM 7080 C  CB  . SER Z 8 .   ? 108.583 147.916 146.389 1.00 74.66  ? 512 SER B CB  1 
HETATM 7081 O  OG  . SER Z 8 .   ? 109.563 148.753 145.802 1.00 76.33  ? 512 SER B OG  1 
HETATM 7082 O  OXT . SER Z 8 .   ? 108.330 150.729 148.350 1.00 76.29  ? 512 SER B OXT 1 
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