data_9KQF
# 
_entry.id   9KQF 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9KQF         pdb_00009kqf 10.2210/pdb9kqf/pdb 
WWPDB D_1300054096 ?            ?                   
EMDB  EMD-62503    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-04-02 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9KQF 
_pdbx_database_status.recvd_initial_deposition_date   2024-11-25 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of PSS1 in the absence of calcium or L-serine' 
_pdbx_database_related.db_id          EMD-62503 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              gejp@shanghaitech.edu.cn 
_pdbx_contact_author.name_first         Jingpeng 
_pdbx_contact_author.name_last          Ge 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-6164-1221 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Ning, Y.' 1 0009-0004-7041-1857 
'Yu, J.'   2 0000-0001-9227-038X 
'Ge, J.'   3 0000-0001-6164-1221 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Cell Discov' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2056-5968 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            11 
_citation.language                  ? 
_citation.page_first                20 
_citation.page_last                 20 
_citation.title                     'Structural basis for catalytic mechanism of human phosphatidylserine synthase 1.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41421-025-00775-3 
_citation.pdbx_database_id_PubMed   40044636 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Ning, Y.' 1 ?                   
primary 'Xu, R.'   2 ?                   
primary 'Yu, J.'   3 0000-0001-9227-038X 
primary 'Ge, J.'   4 0000-0001-6164-1221 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Phosphatidylserine synthase 1'                  55590.383 2  2.7.8.29 ? ? ? 
2 non-polymer syn 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE           455.437   4  ?        ? ? ? 
3 non-polymer syn 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine 760.076   10 ?        ? ? ? 
4 non-polymer syn DODECANE                                         170.335   2  ?        ? ? ? 
5 non-polymer syn TETRADECANE                                      198.388   2  ?        ? ? ? 
6 non-polymer syn Phosphatidylinositol                             887.128   2  ?        ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'PSS-1,PtdSer synthase 1,Serine-exchange enzyme I' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MASCVGSRTLSKDDVNYKMHFRMINEQQVEDITIDFFYRPHTITLLSFTIVSLMYFAFTRDDSVPEDNIWRGILSVIFFF
LIISVLAFPNGPFTRPHPALWRMVFGLSVLYFLFLVFLLFLNFEQVKSLMYWLDPNLRYATREADVMEYAVNCHVITWER
IISHFDIFAFGHFWGWAMKALLIRSYGLCWTISITWELTELFFMHLLPNFAECWWDQVILDILLCNGGGIWLGMVVCRFL
EMRTYHWASFKDIHTTTGKIKRAVLQFTPASWTYVRWFDPKSSFQRVAGVYLFMIIWQLTELNTFFLKHIFVFQASHPLS
WGRILFIGGITAPTVRQYYAYLTDTQCKRVGTQCWVFGVIGFLEAIVCIKFGQDLFSKTQILYVVLWLLCVAFTTFLCLY
GMIWYAEHYGHREKTYSECEDGTYSPEISWHHRKGTKGSEDSPPKHAGNNESHSSRRRNRHSKSKVTNGVGKK
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MASCVGSRTLSKDDVNYKMHFRMINEQQVEDITIDFFYRPHTITLLSFTIVSLMYFAFTRDDSVPEDNIWRGILSVIFFF
LIISVLAFPNGPFTRPHPALWRMVFGLSVLYFLFLVFLLFLNFEQVKSLMYWLDPNLRYATREADVMEYAVNCHVITWER
IISHFDIFAFGHFWGWAMKALLIRSYGLCWTISITWELTELFFMHLLPNFAECWWDQVILDILLCNGGGIWLGMVVCRFL
EMRTYHWASFKDIHTTTGKIKRAVLQFTPASWTYVRWFDPKSSFQRVAGVYLFMIIWQLTELNTFFLKHIFVFQASHPLS
WGRILFIGGITAPTVRQYYAYLTDTQCKRVGTQCWVFGVIGFLEAIVCIKFGQDLFSKTQILYVVLWLLCVAFTTFLCLY
GMIWYAEHYGHREKTYSECEDGTYSPEISWHHRKGTKGSEDSPPKHAGNNESHSSRRRNRHSKSKVTNGVGKK
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE           PSF 
3 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine LBN 
4 DODECANE                                         D12 
5 TETRADECANE                                      C14 
6 Phosphatidylinositol                             T7X 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ALA n 
1 3   SER n 
1 4   CYS n 
1 5   VAL n 
1 6   GLY n 
1 7   SER n 
1 8   ARG n 
1 9   THR n 
1 10  LEU n 
1 11  SER n 
1 12  LYS n 
1 13  ASP n 
1 14  ASP n 
1 15  VAL n 
1 16  ASN n 
1 17  TYR n 
1 18  LYS n 
1 19  MET n 
1 20  HIS n 
1 21  PHE n 
1 22  ARG n 
1 23  MET n 
1 24  ILE n 
1 25  ASN n 
1 26  GLU n 
1 27  GLN n 
1 28  GLN n 
1 29  VAL n 
1 30  GLU n 
1 31  ASP n 
1 32  ILE n 
1 33  THR n 
1 34  ILE n 
1 35  ASP n 
1 36  PHE n 
1 37  PHE n 
1 38  TYR n 
1 39  ARG n 
1 40  PRO n 
1 41  HIS n 
1 42  THR n 
1 43  ILE n 
1 44  THR n 
1 45  LEU n 
1 46  LEU n 
1 47  SER n 
1 48  PHE n 
1 49  THR n 
1 50  ILE n 
1 51  VAL n 
1 52  SER n 
1 53  LEU n 
1 54  MET n 
1 55  TYR n 
1 56  PHE n 
1 57  ALA n 
1 58  PHE n 
1 59  THR n 
1 60  ARG n 
1 61  ASP n 
1 62  ASP n 
1 63  SER n 
1 64  VAL n 
1 65  PRO n 
1 66  GLU n 
1 67  ASP n 
1 68  ASN n 
1 69  ILE n 
1 70  TRP n 
1 71  ARG n 
1 72  GLY n 
1 73  ILE n 
1 74  LEU n 
1 75  SER n 
1 76  VAL n 
1 77  ILE n 
1 78  PHE n 
1 79  PHE n 
1 80  PHE n 
1 81  LEU n 
1 82  ILE n 
1 83  ILE n 
1 84  SER n 
1 85  VAL n 
1 86  LEU n 
1 87  ALA n 
1 88  PHE n 
1 89  PRO n 
1 90  ASN n 
1 91  GLY n 
1 92  PRO n 
1 93  PHE n 
1 94  THR n 
1 95  ARG n 
1 96  PRO n 
1 97  HIS n 
1 98  PRO n 
1 99  ALA n 
1 100 LEU n 
1 101 TRP n 
1 102 ARG n 
1 103 MET n 
1 104 VAL n 
1 105 PHE n 
1 106 GLY n 
1 107 LEU n 
1 108 SER n 
1 109 VAL n 
1 110 LEU n 
1 111 TYR n 
1 112 PHE n 
1 113 LEU n 
1 114 PHE n 
1 115 LEU n 
1 116 VAL n 
1 117 PHE n 
1 118 LEU n 
1 119 LEU n 
1 120 PHE n 
1 121 LEU n 
1 122 ASN n 
1 123 PHE n 
1 124 GLU n 
1 125 GLN n 
1 126 VAL n 
1 127 LYS n 
1 128 SER n 
1 129 LEU n 
1 130 MET n 
1 131 TYR n 
1 132 TRP n 
1 133 LEU n 
1 134 ASP n 
1 135 PRO n 
1 136 ASN n 
1 137 LEU n 
1 138 ARG n 
1 139 TYR n 
1 140 ALA n 
1 141 THR n 
1 142 ARG n 
1 143 GLU n 
1 144 ALA n 
1 145 ASP n 
1 146 VAL n 
1 147 MET n 
1 148 GLU n 
1 149 TYR n 
1 150 ALA n 
1 151 VAL n 
1 152 ASN n 
1 153 CYS n 
1 154 HIS n 
1 155 VAL n 
1 156 ILE n 
1 157 THR n 
1 158 TRP n 
1 159 GLU n 
1 160 ARG n 
1 161 ILE n 
1 162 ILE n 
1 163 SER n 
1 164 HIS n 
1 165 PHE n 
1 166 ASP n 
1 167 ILE n 
1 168 PHE n 
1 169 ALA n 
1 170 PHE n 
1 171 GLY n 
1 172 HIS n 
1 173 PHE n 
1 174 TRP n 
1 175 GLY n 
1 176 TRP n 
1 177 ALA n 
1 178 MET n 
1 179 LYS n 
1 180 ALA n 
1 181 LEU n 
1 182 LEU n 
1 183 ILE n 
1 184 ARG n 
1 185 SER n 
1 186 TYR n 
1 187 GLY n 
1 188 LEU n 
1 189 CYS n 
1 190 TRP n 
1 191 THR n 
1 192 ILE n 
1 193 SER n 
1 194 ILE n 
1 195 THR n 
1 196 TRP n 
1 197 GLU n 
1 198 LEU n 
1 199 THR n 
1 200 GLU n 
1 201 LEU n 
1 202 PHE n 
1 203 PHE n 
1 204 MET n 
1 205 HIS n 
1 206 LEU n 
1 207 LEU n 
1 208 PRO n 
1 209 ASN n 
1 210 PHE n 
1 211 ALA n 
1 212 GLU n 
1 213 CYS n 
1 214 TRP n 
1 215 TRP n 
1 216 ASP n 
1 217 GLN n 
1 218 VAL n 
1 219 ILE n 
1 220 LEU n 
1 221 ASP n 
1 222 ILE n 
1 223 LEU n 
1 224 LEU n 
1 225 CYS n 
1 226 ASN n 
1 227 GLY n 
1 228 GLY n 
1 229 GLY n 
1 230 ILE n 
1 231 TRP n 
1 232 LEU n 
1 233 GLY n 
1 234 MET n 
1 235 VAL n 
1 236 VAL n 
1 237 CYS n 
1 238 ARG n 
1 239 PHE n 
1 240 LEU n 
1 241 GLU n 
1 242 MET n 
1 243 ARG n 
1 244 THR n 
1 245 TYR n 
1 246 HIS n 
1 247 TRP n 
1 248 ALA n 
1 249 SER n 
1 250 PHE n 
1 251 LYS n 
1 252 ASP n 
1 253 ILE n 
1 254 HIS n 
1 255 THR n 
1 256 THR n 
1 257 THR n 
1 258 GLY n 
1 259 LYS n 
1 260 ILE n 
1 261 LYS n 
1 262 ARG n 
1 263 ALA n 
1 264 VAL n 
1 265 LEU n 
1 266 GLN n 
1 267 PHE n 
1 268 THR n 
1 269 PRO n 
1 270 ALA n 
1 271 SER n 
1 272 TRP n 
1 273 THR n 
1 274 TYR n 
1 275 VAL n 
1 276 ARG n 
1 277 TRP n 
1 278 PHE n 
1 279 ASP n 
1 280 PRO n 
1 281 LYS n 
1 282 SER n 
1 283 SER n 
1 284 PHE n 
1 285 GLN n 
1 286 ARG n 
1 287 VAL n 
1 288 ALA n 
1 289 GLY n 
1 290 VAL n 
1 291 TYR n 
1 292 LEU n 
1 293 PHE n 
1 294 MET n 
1 295 ILE n 
1 296 ILE n 
1 297 TRP n 
1 298 GLN n 
1 299 LEU n 
1 300 THR n 
1 301 GLU n 
1 302 LEU n 
1 303 ASN n 
1 304 THR n 
1 305 PHE n 
1 306 PHE n 
1 307 LEU n 
1 308 LYS n 
1 309 HIS n 
1 310 ILE n 
1 311 PHE n 
1 312 VAL n 
1 313 PHE n 
1 314 GLN n 
1 315 ALA n 
1 316 SER n 
1 317 HIS n 
1 318 PRO n 
1 319 LEU n 
1 320 SER n 
1 321 TRP n 
1 322 GLY n 
1 323 ARG n 
1 324 ILE n 
1 325 LEU n 
1 326 PHE n 
1 327 ILE n 
1 328 GLY n 
1 329 GLY n 
1 330 ILE n 
1 331 THR n 
1 332 ALA n 
1 333 PRO n 
1 334 THR n 
1 335 VAL n 
1 336 ARG n 
1 337 GLN n 
1 338 TYR n 
1 339 TYR n 
1 340 ALA n 
1 341 TYR n 
1 342 LEU n 
1 343 THR n 
1 344 ASP n 
1 345 THR n 
1 346 GLN n 
1 347 CYS n 
1 348 LYS n 
1 349 ARG n 
1 350 VAL n 
1 351 GLY n 
1 352 THR n 
1 353 GLN n 
1 354 CYS n 
1 355 TRP n 
1 356 VAL n 
1 357 PHE n 
1 358 GLY n 
1 359 VAL n 
1 360 ILE n 
1 361 GLY n 
1 362 PHE n 
1 363 LEU n 
1 364 GLU n 
1 365 ALA n 
1 366 ILE n 
1 367 VAL n 
1 368 CYS n 
1 369 ILE n 
1 370 LYS n 
1 371 PHE n 
1 372 GLY n 
1 373 GLN n 
1 374 ASP n 
1 375 LEU n 
1 376 PHE n 
1 377 SER n 
1 378 LYS n 
1 379 THR n 
1 380 GLN n 
1 381 ILE n 
1 382 LEU n 
1 383 TYR n 
1 384 VAL n 
1 385 VAL n 
1 386 LEU n 
1 387 TRP n 
1 388 LEU n 
1 389 LEU n 
1 390 CYS n 
1 391 VAL n 
1 392 ALA n 
1 393 PHE n 
1 394 THR n 
1 395 THR n 
1 396 PHE n 
1 397 LEU n 
1 398 CYS n 
1 399 LEU n 
1 400 TYR n 
1 401 GLY n 
1 402 MET n 
1 403 ILE n 
1 404 TRP n 
1 405 TYR n 
1 406 ALA n 
1 407 GLU n 
1 408 HIS n 
1 409 TYR n 
1 410 GLY n 
1 411 HIS n 
1 412 ARG n 
1 413 GLU n 
1 414 LYS n 
1 415 THR n 
1 416 TYR n 
1 417 SER n 
1 418 GLU n 
1 419 CYS n 
1 420 GLU n 
1 421 ASP n 
1 422 GLY n 
1 423 THR n 
1 424 TYR n 
1 425 SER n 
1 426 PRO n 
1 427 GLU n 
1 428 ILE n 
1 429 SER n 
1 430 TRP n 
1 431 HIS n 
1 432 HIS n 
1 433 ARG n 
1 434 LYS n 
1 435 GLY n 
1 436 THR n 
1 437 LYS n 
1 438 GLY n 
1 439 SER n 
1 440 GLU n 
1 441 ASP n 
1 442 SER n 
1 443 PRO n 
1 444 PRO n 
1 445 LYS n 
1 446 HIS n 
1 447 ALA n 
1 448 GLY n 
1 449 ASN n 
1 450 ASN n 
1 451 GLU n 
1 452 SER n 
1 453 HIS n 
1 454 SER n 
1 455 SER n 
1 456 ARG n 
1 457 ARG n 
1 458 ARG n 
1 459 ASN n 
1 460 ARG n 
1 461 HIS n 
1 462 SER n 
1 463 LYS n 
1 464 SER n 
1 465 LYS n 
1 466 VAL n 
1 467 THR n 
1 468 ASN n 
1 469 GLY n 
1 470 VAL n 
1 471 GLY n 
1 472 LYS n 
1 473 LYS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   473 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'PTDSS1, KIAA0024, PSSA' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     9606 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                          ? 'C3 H7 N O2'      89.093  
ARG 'L-peptide linking' y ARGININE                                         ? 'C6 H15 N4 O2 1'  175.209 
ASN 'L-peptide linking' y ASPARAGINE                                       ? 'C4 H8 N2 O3'     132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                                  ? 'C4 H7 N O4'      133.103 
C14 non-polymer         . TETRADECANE                                      ? 'C14 H30'         198.388 
CYS 'L-peptide linking' y CYSTEINE                                         ? 'C3 H7 N O2 S'    121.158 
D12 non-polymer         . DODECANE                                         ? 'C12 H26'         170.335 
GLN 'L-peptide linking' y GLUTAMINE                                        ? 'C5 H10 N2 O3'    146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                                  ? 'C5 H9 N O4'      147.129 
GLY 'peptide linking'   y GLYCINE                                          ? 'C2 H5 N O2'      75.067  
HIS 'L-peptide linking' y HISTIDINE                                        ? 'C6 H10 N3 O2 1'  156.162 
ILE 'L-peptide linking' y ISOLEUCINE                                       ? 'C6 H13 N O2'     131.173 
LBN non-polymer         . 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine 
'(2R)-2-[(9Z)-9-Octadecenoyloxy]-3-(palmitoyloxy)propyl 2-(trimethylammonio)ethyl phosphate' 'C42 H82 N O8 P'  760.076 
LEU 'L-peptide linking' y LEUCINE                                          ? 'C6 H13 N O2'     131.173 
LYS 'L-peptide linking' y LYSINE                                           ? 'C6 H15 N2 O2 1'  147.195 
MET 'L-peptide linking' y METHIONINE                                       ? 'C5 H11 N O2 S'   149.211 
PHE 'L-peptide linking' y PHENYLALANINE                                    ? 'C9 H11 N O2'     165.189 
PRO 'L-peptide linking' y PROLINE                                          ? 'C5 H9 N O2'      115.130 
PSF non-polymer         . 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE           PHOSPHATIDYLSERINE 'C18 H34 N O10 P' 455.437 
SER 'L-peptide linking' y SERINE                                           ? 'C3 H7 N O3'      105.093 
T7X non-polymer         . Phosphatidylinositol                             ? 'C47 H83 O13 P'   887.128 
THR 'L-peptide linking' y THREONINE                                        ? 'C4 H9 N O3'      119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                                       ? 'C11 H12 N2 O2'   204.225 
TYR 'L-peptide linking' y TYROSINE                                         ? 'C9 H11 N O3'     181.189 
VAL 'L-peptide linking' y VALINE                                           ? 'C5 H11 N O2'     117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   ALA 2   2   ?   ?   ?   A . n 
A 1 3   SER 3   3   ?   ?   ?   A . n 
A 1 4   CYS 4   4   ?   ?   ?   A . n 
A 1 5   VAL 5   5   ?   ?   ?   A . n 
A 1 6   GLY 6   6   ?   ?   ?   A . n 
A 1 7   SER 7   7   ?   ?   ?   A . n 
A 1 8   ARG 8   8   ?   ?   ?   A . n 
A 1 9   THR 9   9   ?   ?   ?   A . n 
A 1 10  LEU 10  10  ?   ?   ?   A . n 
A 1 11  SER 11  11  ?   ?   ?   A . n 
A 1 12  LYS 12  12  ?   ?   ?   A . n 
A 1 13  ASP 13  13  ?   ?   ?   A . n 
A 1 14  ASP 14  14  14  ASP ASP A . n 
A 1 15  VAL 15  15  15  VAL VAL A . n 
A 1 16  ASN 16  16  16  ASN ASN A . n 
A 1 17  TYR 17  17  17  TYR TYR A . n 
A 1 18  LYS 18  18  18  LYS LYS A . n 
A 1 19  MET 19  19  19  MET MET A . n 
A 1 20  HIS 20  20  20  HIS HIS A . n 
A 1 21  PHE 21  21  21  PHE PHE A . n 
A 1 22  ARG 22  22  22  ARG ARG A . n 
A 1 23  MET 23  23  23  MET MET A . n 
A 1 24  ILE 24  24  24  ILE ILE A . n 
A 1 25  ASN 25  25  25  ASN ASN A . n 
A 1 26  GLU 26  26  26  GLU GLU A . n 
A 1 27  GLN 27  27  27  GLN GLN A . n 
A 1 28  GLN 28  28  28  GLN GLN A . n 
A 1 29  VAL 29  29  29  VAL VAL A . n 
A 1 30  GLU 30  30  30  GLU GLU A . n 
A 1 31  ASP 31  31  31  ASP ASP A . n 
A 1 32  ILE 32  32  32  ILE ILE A . n 
A 1 33  THR 33  33  33  THR THR A . n 
A 1 34  ILE 34  34  34  ILE ILE A . n 
A 1 35  ASP 35  35  35  ASP ASP A . n 
A 1 36  PHE 36  36  36  PHE PHE A . n 
A 1 37  PHE 37  37  37  PHE PHE A . n 
A 1 38  TYR 38  38  38  TYR TYR A . n 
A 1 39  ARG 39  39  39  ARG ARG A . n 
A 1 40  PRO 40  40  40  PRO PRO A . n 
A 1 41  HIS 41  41  41  HIS HIS A . n 
A 1 42  THR 42  42  42  THR THR A . n 
A 1 43  ILE 43  43  43  ILE ILE A . n 
A 1 44  THR 44  44  44  THR THR A . n 
A 1 45  LEU 45  45  45  LEU LEU A . n 
A 1 46  LEU 46  46  46  LEU LEU A . n 
A 1 47  SER 47  47  47  SER SER A . n 
A 1 48  PHE 48  48  48  PHE PHE A . n 
A 1 49  THR 49  49  49  THR THR A . n 
A 1 50  ILE 50  50  50  ILE ILE A . n 
A 1 51  VAL 51  51  51  VAL VAL A . n 
A 1 52  SER 52  52  52  SER SER A . n 
A 1 53  LEU 53  53  53  LEU LEU A . n 
A 1 54  MET 54  54  54  MET MET A . n 
A 1 55  TYR 55  55  55  TYR TYR A . n 
A 1 56  PHE 56  56  56  PHE PHE A . n 
A 1 57  ALA 57  57  57  ALA ALA A . n 
A 1 58  PHE 58  58  58  PHE PHE A . n 
A 1 59  THR 59  59  59  THR THR A . n 
A 1 60  ARG 60  60  60  ARG ARG A . n 
A 1 61  ASP 61  61  61  ASP ASP A . n 
A 1 62  ASP 62  62  62  ASP ASP A . n 
A 1 63  SER 63  63  63  SER SER A . n 
A 1 64  VAL 64  64  64  VAL VAL A . n 
A 1 65  PRO 65  65  65  PRO PRO A . n 
A 1 66  GLU 66  66  66  GLU GLU A . n 
A 1 67  ASP 67  67  67  ASP ASP A . n 
A 1 68  ASN 68  68  68  ASN ASN A . n 
A 1 69  ILE 69  69  69  ILE ILE A . n 
A 1 70  TRP 70  70  70  TRP TRP A . n 
A 1 71  ARG 71  71  71  ARG ARG A . n 
A 1 72  GLY 72  72  72  GLY GLY A . n 
A 1 73  ILE 73  73  73  ILE ILE A . n 
A 1 74  LEU 74  74  74  LEU LEU A . n 
A 1 75  SER 75  75  75  SER SER A . n 
A 1 76  VAL 76  76  76  VAL VAL A . n 
A 1 77  ILE 77  77  77  ILE ILE A . n 
A 1 78  PHE 78  78  78  PHE PHE A . n 
A 1 79  PHE 79  79  79  PHE PHE A . n 
A 1 80  PHE 80  80  80  PHE PHE A . n 
A 1 81  LEU 81  81  81  LEU LEU A . n 
A 1 82  ILE 82  82  82  ILE ILE A . n 
A 1 83  ILE 83  83  83  ILE ILE A . n 
A 1 84  SER 84  84  84  SER SER A . n 
A 1 85  VAL 85  85  85  VAL VAL A . n 
A 1 86  LEU 86  86  86  LEU LEU A . n 
A 1 87  ALA 87  87  87  ALA ALA A . n 
A 1 88  PHE 88  88  88  PHE PHE A . n 
A 1 89  PRO 89  89  89  PRO PRO A . n 
A 1 90  ASN 90  90  90  ASN ASN A . n 
A 1 91  GLY 91  91  91  GLY GLY A . n 
A 1 92  PRO 92  92  92  PRO PRO A . n 
A 1 93  PHE 93  93  93  PHE PHE A . n 
A 1 94  THR 94  94  94  THR THR A . n 
A 1 95  ARG 95  95  95  ARG ARG A . n 
A 1 96  PRO 96  96  96  PRO PRO A . n 
A 1 97  HIS 97  97  97  HIS HIS A . n 
A 1 98  PRO 98  98  98  PRO PRO A . n 
A 1 99  ALA 99  99  99  ALA ALA A . n 
A 1 100 LEU 100 100 100 LEU LEU A . n 
A 1 101 TRP 101 101 101 TRP TRP A . n 
A 1 102 ARG 102 102 102 ARG ARG A . n 
A 1 103 MET 103 103 103 MET MET A . n 
A 1 104 VAL 104 104 104 VAL VAL A . n 
A 1 105 PHE 105 105 105 PHE PHE A . n 
A 1 106 GLY 106 106 106 GLY GLY A . n 
A 1 107 LEU 107 107 107 LEU LEU A . n 
A 1 108 SER 108 108 108 SER SER A . n 
A 1 109 VAL 109 109 109 VAL VAL A . n 
A 1 110 LEU 110 110 110 LEU LEU A . n 
A 1 111 TYR 111 111 111 TYR TYR A . n 
A 1 112 PHE 112 112 112 PHE PHE A . n 
A 1 113 LEU 113 113 113 LEU LEU A . n 
A 1 114 PHE 114 114 114 PHE PHE A . n 
A 1 115 LEU 115 115 115 LEU LEU A . n 
A 1 116 VAL 116 116 116 VAL VAL A . n 
A 1 117 PHE 117 117 117 PHE PHE A . n 
A 1 118 LEU 118 118 118 LEU LEU A . n 
A 1 119 LEU 119 119 119 LEU LEU A . n 
A 1 120 PHE 120 120 120 PHE PHE A . n 
A 1 121 LEU 121 121 121 LEU LEU A . n 
A 1 122 ASN 122 122 122 ASN ASN A . n 
A 1 123 PHE 123 123 123 PHE PHE A . n 
A 1 124 GLU 124 124 124 GLU GLU A . n 
A 1 125 GLN 125 125 125 GLN GLN A . n 
A 1 126 VAL 126 126 126 VAL VAL A . n 
A 1 127 LYS 127 127 127 LYS LYS A . n 
A 1 128 SER 128 128 128 SER SER A . n 
A 1 129 LEU 129 129 129 LEU LEU A . n 
A 1 130 MET 130 130 130 MET MET A . n 
A 1 131 TYR 131 131 131 TYR TYR A . n 
A 1 132 TRP 132 132 132 TRP TRP A . n 
A 1 133 LEU 133 133 133 LEU LEU A . n 
A 1 134 ASP 134 134 134 ASP ASP A . n 
A 1 135 PRO 135 135 135 PRO PRO A . n 
A 1 136 ASN 136 136 136 ASN ASN A . n 
A 1 137 LEU 137 137 137 LEU LEU A . n 
A 1 138 ARG 138 138 138 ARG ARG A . n 
A 1 139 TYR 139 139 139 TYR TYR A . n 
A 1 140 ALA 140 140 140 ALA ALA A . n 
A 1 141 THR 141 141 ?   ?   ?   A . n 
A 1 142 ARG 142 142 ?   ?   ?   A . n 
A 1 143 GLU 143 143 ?   ?   ?   A . n 
A 1 144 ALA 144 144 ?   ?   ?   A . n 
A 1 145 ASP 145 145 ?   ?   ?   A . n 
A 1 146 VAL 146 146 ?   ?   ?   A . n 
A 1 147 MET 147 147 ?   ?   ?   A . n 
A 1 148 GLU 148 148 ?   ?   ?   A . n 
A 1 149 TYR 149 149 ?   ?   ?   A . n 
A 1 150 ALA 150 150 ?   ?   ?   A . n 
A 1 151 VAL 151 151 ?   ?   ?   A . n 
A 1 152 ASN 152 152 ?   ?   ?   A . n 
A 1 153 CYS 153 153 ?   ?   ?   A . n 
A 1 154 HIS 154 154 ?   ?   ?   A . n 
A 1 155 VAL 155 155 ?   ?   ?   A . n 
A 1 156 ILE 156 156 ?   ?   ?   A . n 
A 1 157 THR 157 157 ?   ?   ?   A . n 
A 1 158 TRP 158 158 ?   ?   ?   A . n 
A 1 159 GLU 159 159 159 GLU GLU A . n 
A 1 160 ARG 160 160 160 ARG ARG A . n 
A 1 161 ILE 161 161 161 ILE ILE A . n 
A 1 162 ILE 162 162 162 ILE ILE A . n 
A 1 163 SER 163 163 163 SER SER A . n 
A 1 164 HIS 164 164 164 HIS HIS A . n 
A 1 165 PHE 165 165 165 PHE PHE A . n 
A 1 166 ASP 166 166 166 ASP ASP A . n 
A 1 167 ILE 167 167 167 ILE ILE A . n 
A 1 168 PHE 168 168 168 PHE PHE A . n 
A 1 169 ALA 169 169 169 ALA ALA A . n 
A 1 170 PHE 170 170 170 PHE PHE A . n 
A 1 171 GLY 171 171 171 GLY GLY A . n 
A 1 172 HIS 172 172 172 HIS HIS A . n 
A 1 173 PHE 173 173 173 PHE PHE A . n 
A 1 174 TRP 174 174 174 TRP TRP A . n 
A 1 175 GLY 175 175 175 GLY GLY A . n 
A 1 176 TRP 176 176 176 TRP TRP A . n 
A 1 177 ALA 177 177 177 ALA ALA A . n 
A 1 178 MET 178 178 178 MET MET A . n 
A 1 179 LYS 179 179 179 LYS LYS A . n 
A 1 180 ALA 180 180 180 ALA ALA A . n 
A 1 181 LEU 181 181 181 LEU LEU A . n 
A 1 182 LEU 182 182 182 LEU LEU A . n 
A 1 183 ILE 183 183 183 ILE ILE A . n 
A 1 184 ARG 184 184 184 ARG ARG A . n 
A 1 185 SER 185 185 185 SER SER A . n 
A 1 186 TYR 186 186 186 TYR TYR A . n 
A 1 187 GLY 187 187 187 GLY GLY A . n 
A 1 188 LEU 188 188 188 LEU LEU A . n 
A 1 189 CYS 189 189 189 CYS CYS A . n 
A 1 190 TRP 190 190 190 TRP TRP A . n 
A 1 191 THR 191 191 191 THR THR A . n 
A 1 192 ILE 192 192 192 ILE ILE A . n 
A 1 193 SER 193 193 193 SER SER A . n 
A 1 194 ILE 194 194 194 ILE ILE A . n 
A 1 195 THR 195 195 195 THR THR A . n 
A 1 196 TRP 196 196 196 TRP TRP A . n 
A 1 197 GLU 197 197 197 GLU GLU A . n 
A 1 198 LEU 198 198 198 LEU LEU A . n 
A 1 199 THR 199 199 199 THR THR A . n 
A 1 200 GLU 200 200 200 GLU GLU A . n 
A 1 201 LEU 201 201 201 LEU LEU A . n 
A 1 202 PHE 202 202 202 PHE PHE A . n 
A 1 203 PHE 203 203 203 PHE PHE A . n 
A 1 204 MET 204 204 204 MET MET A . n 
A 1 205 HIS 205 205 205 HIS HIS A . n 
A 1 206 LEU 206 206 206 LEU LEU A . n 
A 1 207 LEU 207 207 207 LEU LEU A . n 
A 1 208 PRO 208 208 208 PRO PRO A . n 
A 1 209 ASN 209 209 209 ASN ASN A . n 
A 1 210 PHE 210 210 210 PHE PHE A . n 
A 1 211 ALA 211 211 211 ALA ALA A . n 
A 1 212 GLU 212 212 212 GLU GLU A . n 
A 1 213 CYS 213 213 213 CYS CYS A . n 
A 1 214 TRP 214 214 214 TRP TRP A . n 
A 1 215 TRP 215 215 215 TRP TRP A . n 
A 1 216 ASP 216 216 216 ASP ASP A . n 
A 1 217 GLN 217 217 217 GLN GLN A . n 
A 1 218 VAL 218 218 218 VAL VAL A . n 
A 1 219 ILE 219 219 219 ILE ILE A . n 
A 1 220 LEU 220 220 220 LEU LEU A . n 
A 1 221 ASP 221 221 221 ASP ASP A . n 
A 1 222 ILE 222 222 222 ILE ILE A . n 
A 1 223 LEU 223 223 223 LEU LEU A . n 
A 1 224 LEU 224 224 224 LEU LEU A . n 
A 1 225 CYS 225 225 225 CYS CYS A . n 
A 1 226 ASN 226 226 226 ASN ASN A . n 
A 1 227 GLY 227 227 227 GLY GLY A . n 
A 1 228 GLY 228 228 228 GLY GLY A . n 
A 1 229 GLY 229 229 229 GLY GLY A . n 
A 1 230 ILE 230 230 230 ILE ILE A . n 
A 1 231 TRP 231 231 231 TRP TRP A . n 
A 1 232 LEU 232 232 232 LEU LEU A . n 
A 1 233 GLY 233 233 233 GLY GLY A . n 
A 1 234 MET 234 234 234 MET MET A . n 
A 1 235 VAL 235 235 235 VAL VAL A . n 
A 1 236 VAL 236 236 236 VAL VAL A . n 
A 1 237 CYS 237 237 237 CYS CYS A . n 
A 1 238 ARG 238 238 238 ARG ARG A . n 
A 1 239 PHE 239 239 239 PHE PHE A . n 
A 1 240 LEU 240 240 240 LEU LEU A . n 
A 1 241 GLU 241 241 241 GLU GLU A . n 
A 1 242 MET 242 242 242 MET MET A . n 
A 1 243 ARG 243 243 243 ARG ARG A . n 
A 1 244 THR 244 244 244 THR THR A . n 
A 1 245 TYR 245 245 245 TYR TYR A . n 
A 1 246 HIS 246 246 246 HIS HIS A . n 
A 1 247 TRP 247 247 247 TRP TRP A . n 
A 1 248 ALA 248 248 248 ALA ALA A . n 
A 1 249 SER 249 249 249 SER SER A . n 
A 1 250 PHE 250 250 250 PHE PHE A . n 
A 1 251 LYS 251 251 251 LYS LYS A . n 
A 1 252 ASP 252 252 252 ASP ASP A . n 
A 1 253 ILE 253 253 253 ILE ILE A . n 
A 1 254 HIS 254 254 254 HIS HIS A . n 
A 1 255 THR 255 255 255 THR THR A . n 
A 1 256 THR 256 256 256 THR THR A . n 
A 1 257 THR 257 257 257 THR THR A . n 
A 1 258 GLY 258 258 258 GLY GLY A . n 
A 1 259 LYS 259 259 259 LYS LYS A . n 
A 1 260 ILE 260 260 260 ILE ILE A . n 
A 1 261 LYS 261 261 261 LYS LYS A . n 
A 1 262 ARG 262 262 262 ARG ARG A . n 
A 1 263 ALA 263 263 263 ALA ALA A . n 
A 1 264 VAL 264 264 264 VAL VAL A . n 
A 1 265 LEU 265 265 265 LEU LEU A . n 
A 1 266 GLN 266 266 266 GLN GLN A . n 
A 1 267 PHE 267 267 267 PHE PHE A . n 
A 1 268 THR 268 268 268 THR THR A . n 
A 1 269 PRO 269 269 269 PRO PRO A . n 
A 1 270 ALA 270 270 270 ALA ALA A . n 
A 1 271 SER 271 271 271 SER SER A . n 
A 1 272 TRP 272 272 272 TRP TRP A . n 
A 1 273 THR 273 273 273 THR THR A . n 
A 1 274 TYR 274 274 274 TYR TYR A . n 
A 1 275 VAL 275 275 275 VAL VAL A . n 
A 1 276 ARG 276 276 276 ARG ARG A . n 
A 1 277 TRP 277 277 277 TRP TRP A . n 
A 1 278 PHE 278 278 278 PHE PHE A . n 
A 1 279 ASP 279 279 279 ASP ASP A . n 
A 1 280 PRO 280 280 280 PRO PRO A . n 
A 1 281 LYS 281 281 281 LYS LYS A . n 
A 1 282 SER 282 282 282 SER SER A . n 
A 1 283 SER 283 283 283 SER SER A . n 
A 1 284 PHE 284 284 284 PHE PHE A . n 
A 1 285 GLN 285 285 285 GLN GLN A . n 
A 1 286 ARG 286 286 286 ARG ARG A . n 
A 1 287 VAL 287 287 287 VAL VAL A . n 
A 1 288 ALA 288 288 288 ALA ALA A . n 
A 1 289 GLY 289 289 289 GLY GLY A . n 
A 1 290 VAL 290 290 290 VAL VAL A . n 
A 1 291 TYR 291 291 291 TYR TYR A . n 
A 1 292 LEU 292 292 292 LEU LEU A . n 
A 1 293 PHE 293 293 293 PHE PHE A . n 
A 1 294 MET 294 294 294 MET MET A . n 
A 1 295 ILE 295 295 295 ILE ILE A . n 
A 1 296 ILE 296 296 296 ILE ILE A . n 
A 1 297 TRP 297 297 297 TRP TRP A . n 
A 1 298 GLN 298 298 298 GLN GLN A . n 
A 1 299 LEU 299 299 299 LEU LEU A . n 
A 1 300 THR 300 300 300 THR THR A . n 
A 1 301 GLU 301 301 301 GLU GLU A . n 
A 1 302 LEU 302 302 302 LEU LEU A . n 
A 1 303 ASN 303 303 303 ASN ASN A . n 
A 1 304 THR 304 304 304 THR THR A . n 
A 1 305 PHE 305 305 305 PHE PHE A . n 
A 1 306 PHE 306 306 306 PHE PHE A . n 
A 1 307 LEU 307 307 307 LEU LEU A . n 
A 1 308 LYS 308 308 308 LYS LYS A . n 
A 1 309 HIS 309 309 309 HIS HIS A . n 
A 1 310 ILE 310 310 310 ILE ILE A . n 
A 1 311 PHE 311 311 311 PHE PHE A . n 
A 1 312 VAL 312 312 312 VAL VAL A . n 
A 1 313 PHE 313 313 313 PHE PHE A . n 
A 1 314 GLN 314 314 314 GLN GLN A . n 
A 1 315 ALA 315 315 315 ALA ALA A . n 
A 1 316 SER 316 316 316 SER SER A . n 
A 1 317 HIS 317 317 317 HIS HIS A . n 
A 1 318 PRO 318 318 318 PRO PRO A . n 
A 1 319 LEU 319 319 319 LEU LEU A . n 
A 1 320 SER 320 320 320 SER SER A . n 
A 1 321 TRP 321 321 321 TRP TRP A . n 
A 1 322 GLY 322 322 322 GLY GLY A . n 
A 1 323 ARG 323 323 323 ARG ARG A . n 
A 1 324 ILE 324 324 324 ILE ILE A . n 
A 1 325 LEU 325 325 325 LEU LEU A . n 
A 1 326 PHE 326 326 326 PHE PHE A . n 
A 1 327 ILE 327 327 327 ILE ILE A . n 
A 1 328 GLY 328 328 328 GLY GLY A . n 
A 1 329 GLY 329 329 329 GLY GLY A . n 
A 1 330 ILE 330 330 330 ILE ILE A . n 
A 1 331 THR 331 331 331 THR THR A . n 
A 1 332 ALA 332 332 332 ALA ALA A . n 
A 1 333 PRO 333 333 333 PRO PRO A . n 
A 1 334 THR 334 334 334 THR THR A . n 
A 1 335 VAL 335 335 335 VAL VAL A . n 
A 1 336 ARG 336 336 336 ARG ARG A . n 
A 1 337 GLN 337 337 337 GLN GLN A . n 
A 1 338 TYR 338 338 338 TYR TYR A . n 
A 1 339 TYR 339 339 339 TYR TYR A . n 
A 1 340 ALA 340 340 340 ALA ALA A . n 
A 1 341 TYR 341 341 341 TYR TYR A . n 
A 1 342 LEU 342 342 342 LEU LEU A . n 
A 1 343 THR 343 343 343 THR THR A . n 
A 1 344 ASP 344 344 344 ASP ASP A . n 
A 1 345 THR 345 345 345 THR THR A . n 
A 1 346 GLN 346 346 346 GLN GLN A . n 
A 1 347 CYS 347 347 347 CYS CYS A . n 
A 1 348 LYS 348 348 348 LYS LYS A . n 
A 1 349 ARG 349 349 349 ARG ARG A . n 
A 1 350 VAL 350 350 350 VAL VAL A . n 
A 1 351 GLY 351 351 351 GLY GLY A . n 
A 1 352 THR 352 352 352 THR THR A . n 
A 1 353 GLN 353 353 353 GLN GLN A . n 
A 1 354 CYS 354 354 354 CYS CYS A . n 
A 1 355 TRP 355 355 355 TRP TRP A . n 
A 1 356 VAL 356 356 356 VAL VAL A . n 
A 1 357 PHE 357 357 357 PHE PHE A . n 
A 1 358 GLY 358 358 358 GLY GLY A . n 
A 1 359 VAL 359 359 359 VAL VAL A . n 
A 1 360 ILE 360 360 360 ILE ILE A . n 
A 1 361 GLY 361 361 361 GLY GLY A . n 
A 1 362 PHE 362 362 362 PHE PHE A . n 
A 1 363 LEU 363 363 363 LEU LEU A . n 
A 1 364 GLU 364 364 364 GLU GLU A . n 
A 1 365 ALA 365 365 365 ALA ALA A . n 
A 1 366 ILE 366 366 366 ILE ILE A . n 
A 1 367 VAL 367 367 367 VAL VAL A . n 
A 1 368 CYS 368 368 368 CYS CYS A . n 
A 1 369 ILE 369 369 369 ILE ILE A . n 
A 1 370 LYS 370 370 370 LYS LYS A . n 
A 1 371 PHE 371 371 371 PHE PHE A . n 
A 1 372 GLY 372 372 372 GLY GLY A . n 
A 1 373 GLN 373 373 373 GLN GLN A . n 
A 1 374 ASP 374 374 374 ASP ASP A . n 
A 1 375 LEU 375 375 375 LEU LEU A . n 
A 1 376 PHE 376 376 376 PHE PHE A . n 
A 1 377 SER 377 377 377 SER SER A . n 
A 1 378 LYS 378 378 378 LYS LYS A . n 
A 1 379 THR 379 379 379 THR THR A . n 
A 1 380 GLN 380 380 380 GLN GLN A . n 
A 1 381 ILE 381 381 381 ILE ILE A . n 
A 1 382 LEU 382 382 382 LEU LEU A . n 
A 1 383 TYR 383 383 383 TYR TYR A . n 
A 1 384 VAL 384 384 384 VAL VAL A . n 
A 1 385 VAL 385 385 385 VAL VAL A . n 
A 1 386 LEU 386 386 386 LEU LEU A . n 
A 1 387 TRP 387 387 387 TRP TRP A . n 
A 1 388 LEU 388 388 388 LEU LEU A . n 
A 1 389 LEU 389 389 389 LEU LEU A . n 
A 1 390 CYS 390 390 390 CYS CYS A . n 
A 1 391 VAL 391 391 391 VAL VAL A . n 
A 1 392 ALA 392 392 392 ALA ALA A . n 
A 1 393 PHE 393 393 393 PHE PHE A . n 
A 1 394 THR 394 394 394 THR THR A . n 
A 1 395 THR 395 395 395 THR THR A . n 
A 1 396 PHE 396 396 396 PHE PHE A . n 
A 1 397 LEU 397 397 397 LEU LEU A . n 
A 1 398 CYS 398 398 398 CYS CYS A . n 
A 1 399 LEU 399 399 399 LEU LEU A . n 
A 1 400 TYR 400 400 400 TYR TYR A . n 
A 1 401 GLY 401 401 401 GLY GLY A . n 
A 1 402 MET 402 402 402 MET MET A . n 
A 1 403 ILE 403 403 403 ILE ILE A . n 
A 1 404 TRP 404 404 404 TRP TRP A . n 
A 1 405 TYR 405 405 405 TYR TYR A . n 
A 1 406 ALA 406 406 406 ALA ALA A . n 
A 1 407 GLU 407 407 407 GLU GLU A . n 
A 1 408 HIS 408 408 408 HIS HIS A . n 
A 1 409 TYR 409 409 ?   ?   ?   A . n 
A 1 410 GLY 410 410 ?   ?   ?   A . n 
A 1 411 HIS 411 411 ?   ?   ?   A . n 
A 1 412 ARG 412 412 ?   ?   ?   A . n 
A 1 413 GLU 413 413 ?   ?   ?   A . n 
A 1 414 LYS 414 414 ?   ?   ?   A . n 
A 1 415 THR 415 415 ?   ?   ?   A . n 
A 1 416 TYR 416 416 ?   ?   ?   A . n 
A 1 417 SER 417 417 ?   ?   ?   A . n 
A 1 418 GLU 418 418 ?   ?   ?   A . n 
A 1 419 CYS 419 419 ?   ?   ?   A . n 
A 1 420 GLU 420 420 ?   ?   ?   A . n 
A 1 421 ASP 421 421 ?   ?   ?   A . n 
A 1 422 GLY 422 422 ?   ?   ?   A . n 
A 1 423 THR 423 423 ?   ?   ?   A . n 
A 1 424 TYR 424 424 ?   ?   ?   A . n 
A 1 425 SER 425 425 ?   ?   ?   A . n 
A 1 426 PRO 426 426 ?   ?   ?   A . n 
A 1 427 GLU 427 427 ?   ?   ?   A . n 
A 1 428 ILE 428 428 ?   ?   ?   A . n 
A 1 429 SER 429 429 ?   ?   ?   A . n 
A 1 430 TRP 430 430 ?   ?   ?   A . n 
A 1 431 HIS 431 431 ?   ?   ?   A . n 
A 1 432 HIS 432 432 ?   ?   ?   A . n 
A 1 433 ARG 433 433 ?   ?   ?   A . n 
A 1 434 LYS 434 434 ?   ?   ?   A . n 
A 1 435 GLY 435 435 ?   ?   ?   A . n 
A 1 436 THR 436 436 ?   ?   ?   A . n 
A 1 437 LYS 437 437 ?   ?   ?   A . n 
A 1 438 GLY 438 438 ?   ?   ?   A . n 
A 1 439 SER 439 439 ?   ?   ?   A . n 
A 1 440 GLU 440 440 ?   ?   ?   A . n 
A 1 441 ASP 441 441 ?   ?   ?   A . n 
A 1 442 SER 442 442 ?   ?   ?   A . n 
A 1 443 PRO 443 443 ?   ?   ?   A . n 
A 1 444 PRO 444 444 ?   ?   ?   A . n 
A 1 445 LYS 445 445 ?   ?   ?   A . n 
A 1 446 HIS 446 446 ?   ?   ?   A . n 
A 1 447 ALA 447 447 ?   ?   ?   A . n 
A 1 448 GLY 448 448 ?   ?   ?   A . n 
A 1 449 ASN 449 449 ?   ?   ?   A . n 
A 1 450 ASN 450 450 ?   ?   ?   A . n 
A 1 451 GLU 451 451 ?   ?   ?   A . n 
A 1 452 SER 452 452 ?   ?   ?   A . n 
A 1 453 HIS 453 453 ?   ?   ?   A . n 
A 1 454 SER 454 454 ?   ?   ?   A . n 
A 1 455 SER 455 455 ?   ?   ?   A . n 
A 1 456 ARG 456 456 ?   ?   ?   A . n 
A 1 457 ARG 457 457 ?   ?   ?   A . n 
A 1 458 ARG 458 458 ?   ?   ?   A . n 
A 1 459 ASN 459 459 ?   ?   ?   A . n 
A 1 460 ARG 460 460 ?   ?   ?   A . n 
A 1 461 HIS 461 461 ?   ?   ?   A . n 
A 1 462 SER 462 462 ?   ?   ?   A . n 
A 1 463 LYS 463 463 ?   ?   ?   A . n 
A 1 464 SER 464 464 ?   ?   ?   A . n 
A 1 465 LYS 465 465 ?   ?   ?   A . n 
A 1 466 VAL 466 466 ?   ?   ?   A . n 
A 1 467 THR 467 467 ?   ?   ?   A . n 
A 1 468 ASN 468 468 ?   ?   ?   A . n 
A 1 469 GLY 469 469 ?   ?   ?   A . n 
A 1 470 VAL 470 470 ?   ?   ?   A . n 
A 1 471 GLY 471 471 ?   ?   ?   A . n 
A 1 472 LYS 472 472 ?   ?   ?   A . n 
A 1 473 LYS 473 473 ?   ?   ?   A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   ALA 2   2   ?   ?   ?   B . n 
B 1 3   SER 3   3   ?   ?   ?   B . n 
B 1 4   CYS 4   4   ?   ?   ?   B . n 
B 1 5   VAL 5   5   ?   ?   ?   B . n 
B 1 6   GLY 6   6   ?   ?   ?   B . n 
B 1 7   SER 7   7   ?   ?   ?   B . n 
B 1 8   ARG 8   8   ?   ?   ?   B . n 
B 1 9   THR 9   9   ?   ?   ?   B . n 
B 1 10  LEU 10  10  ?   ?   ?   B . n 
B 1 11  SER 11  11  ?   ?   ?   B . n 
B 1 12  LYS 12  12  ?   ?   ?   B . n 
B 1 13  ASP 13  13  ?   ?   ?   B . n 
B 1 14  ASP 14  14  14  ASP ASP B . n 
B 1 15  VAL 15  15  15  VAL VAL B . n 
B 1 16  ASN 16  16  16  ASN ASN B . n 
B 1 17  TYR 17  17  17  TYR TYR B . n 
B 1 18  LYS 18  18  18  LYS LYS B . n 
B 1 19  MET 19  19  19  MET MET B . n 
B 1 20  HIS 20  20  20  HIS HIS B . n 
B 1 21  PHE 21  21  21  PHE PHE B . n 
B 1 22  ARG 22  22  22  ARG ARG B . n 
B 1 23  MET 23  23  23  MET MET B . n 
B 1 24  ILE 24  24  24  ILE ILE B . n 
B 1 25  ASN 25  25  25  ASN ASN B . n 
B 1 26  GLU 26  26  26  GLU GLU B . n 
B 1 27  GLN 27  27  27  GLN GLN B . n 
B 1 28  GLN 28  28  28  GLN GLN B . n 
B 1 29  VAL 29  29  29  VAL VAL B . n 
B 1 30  GLU 30  30  30  GLU GLU B . n 
B 1 31  ASP 31  31  31  ASP ASP B . n 
B 1 32  ILE 32  32  32  ILE ILE B . n 
B 1 33  THR 33  33  33  THR THR B . n 
B 1 34  ILE 34  34  34  ILE ILE B . n 
B 1 35  ASP 35  35  35  ASP ASP B . n 
B 1 36  PHE 36  36  36  PHE PHE B . n 
B 1 37  PHE 37  37  37  PHE PHE B . n 
B 1 38  TYR 38  38  38  TYR TYR B . n 
B 1 39  ARG 39  39  39  ARG ARG B . n 
B 1 40  PRO 40  40  40  PRO PRO B . n 
B 1 41  HIS 41  41  41  HIS HIS B . n 
B 1 42  THR 42  42  42  THR THR B . n 
B 1 43  ILE 43  43  43  ILE ILE B . n 
B 1 44  THR 44  44  44  THR THR B . n 
B 1 45  LEU 45  45  45  LEU LEU B . n 
B 1 46  LEU 46  46  46  LEU LEU B . n 
B 1 47  SER 47  47  47  SER SER B . n 
B 1 48  PHE 48  48  48  PHE PHE B . n 
B 1 49  THR 49  49  49  THR THR B . n 
B 1 50  ILE 50  50  50  ILE ILE B . n 
B 1 51  VAL 51  51  51  VAL VAL B . n 
B 1 52  SER 52  52  52  SER SER B . n 
B 1 53  LEU 53  53  53  LEU LEU B . n 
B 1 54  MET 54  54  54  MET MET B . n 
B 1 55  TYR 55  55  55  TYR TYR B . n 
B 1 56  PHE 56  56  56  PHE PHE B . n 
B 1 57  ALA 57  57  57  ALA ALA B . n 
B 1 58  PHE 58  58  58  PHE PHE B . n 
B 1 59  THR 59  59  59  THR THR B . n 
B 1 60  ARG 60  60  60  ARG ARG B . n 
B 1 61  ASP 61  61  61  ASP ASP B . n 
B 1 62  ASP 62  62  62  ASP ASP B . n 
B 1 63  SER 63  63  63  SER SER B . n 
B 1 64  VAL 64  64  64  VAL VAL B . n 
B 1 65  PRO 65  65  65  PRO PRO B . n 
B 1 66  GLU 66  66  66  GLU GLU B . n 
B 1 67  ASP 67  67  67  ASP ASP B . n 
B 1 68  ASN 68  68  68  ASN ASN B . n 
B 1 69  ILE 69  69  69  ILE ILE B . n 
B 1 70  TRP 70  70  70  TRP TRP B . n 
B 1 71  ARG 71  71  71  ARG ARG B . n 
B 1 72  GLY 72  72  72  GLY GLY B . n 
B 1 73  ILE 73  73  73  ILE ILE B . n 
B 1 74  LEU 74  74  74  LEU LEU B . n 
B 1 75  SER 75  75  75  SER SER B . n 
B 1 76  VAL 76  76  76  VAL VAL B . n 
B 1 77  ILE 77  77  77  ILE ILE B . n 
B 1 78  PHE 78  78  78  PHE PHE B . n 
B 1 79  PHE 79  79  79  PHE PHE B . n 
B 1 80  PHE 80  80  80  PHE PHE B . n 
B 1 81  LEU 81  81  81  LEU LEU B . n 
B 1 82  ILE 82  82  82  ILE ILE B . n 
B 1 83  ILE 83  83  83  ILE ILE B . n 
B 1 84  SER 84  84  84  SER SER B . n 
B 1 85  VAL 85  85  85  VAL VAL B . n 
B 1 86  LEU 86  86  86  LEU LEU B . n 
B 1 87  ALA 87  87  87  ALA ALA B . n 
B 1 88  PHE 88  88  88  PHE PHE B . n 
B 1 89  PRO 89  89  89  PRO PRO B . n 
B 1 90  ASN 90  90  90  ASN ASN B . n 
B 1 91  GLY 91  91  91  GLY GLY B . n 
B 1 92  PRO 92  92  92  PRO PRO B . n 
B 1 93  PHE 93  93  93  PHE PHE B . n 
B 1 94  THR 94  94  94  THR THR B . n 
B 1 95  ARG 95  95  95  ARG ARG B . n 
B 1 96  PRO 96  96  96  PRO PRO B . n 
B 1 97  HIS 97  97  97  HIS HIS B . n 
B 1 98  PRO 98  98  98  PRO PRO B . n 
B 1 99  ALA 99  99  99  ALA ALA B . n 
B 1 100 LEU 100 100 100 LEU LEU B . n 
B 1 101 TRP 101 101 101 TRP TRP B . n 
B 1 102 ARG 102 102 102 ARG ARG B . n 
B 1 103 MET 103 103 103 MET MET B . n 
B 1 104 VAL 104 104 104 VAL VAL B . n 
B 1 105 PHE 105 105 105 PHE PHE B . n 
B 1 106 GLY 106 106 106 GLY GLY B . n 
B 1 107 LEU 107 107 107 LEU LEU B . n 
B 1 108 SER 108 108 108 SER SER B . n 
B 1 109 VAL 109 109 109 VAL VAL B . n 
B 1 110 LEU 110 110 110 LEU LEU B . n 
B 1 111 TYR 111 111 111 TYR TYR B . n 
B 1 112 PHE 112 112 112 PHE PHE B . n 
B 1 113 LEU 113 113 113 LEU LEU B . n 
B 1 114 PHE 114 114 114 PHE PHE B . n 
B 1 115 LEU 115 115 115 LEU LEU B . n 
B 1 116 VAL 116 116 116 VAL VAL B . n 
B 1 117 PHE 117 117 117 PHE PHE B . n 
B 1 118 LEU 118 118 118 LEU LEU B . n 
B 1 119 LEU 119 119 119 LEU LEU B . n 
B 1 120 PHE 120 120 120 PHE PHE B . n 
B 1 121 LEU 121 121 121 LEU LEU B . n 
B 1 122 ASN 122 122 122 ASN ASN B . n 
B 1 123 PHE 123 123 123 PHE PHE B . n 
B 1 124 GLU 124 124 124 GLU GLU B . n 
B 1 125 GLN 125 125 125 GLN GLN B . n 
B 1 126 VAL 126 126 126 VAL VAL B . n 
B 1 127 LYS 127 127 127 LYS LYS B . n 
B 1 128 SER 128 128 128 SER SER B . n 
B 1 129 LEU 129 129 129 LEU LEU B . n 
B 1 130 MET 130 130 130 MET MET B . n 
B 1 131 TYR 131 131 131 TYR TYR B . n 
B 1 132 TRP 132 132 132 TRP TRP B . n 
B 1 133 LEU 133 133 133 LEU LEU B . n 
B 1 134 ASP 134 134 134 ASP ASP B . n 
B 1 135 PRO 135 135 135 PRO PRO B . n 
B 1 136 ASN 136 136 136 ASN ASN B . n 
B 1 137 LEU 137 137 137 LEU LEU B . n 
B 1 138 ARG 138 138 138 ARG ARG B . n 
B 1 139 TYR 139 139 139 TYR TYR B . n 
B 1 140 ALA 140 140 140 ALA ALA B . n 
B 1 141 THR 141 141 ?   ?   ?   B . n 
B 1 142 ARG 142 142 ?   ?   ?   B . n 
B 1 143 GLU 143 143 ?   ?   ?   B . n 
B 1 144 ALA 144 144 ?   ?   ?   B . n 
B 1 145 ASP 145 145 ?   ?   ?   B . n 
B 1 146 VAL 146 146 ?   ?   ?   B . n 
B 1 147 MET 147 147 ?   ?   ?   B . n 
B 1 148 GLU 148 148 ?   ?   ?   B . n 
B 1 149 TYR 149 149 ?   ?   ?   B . n 
B 1 150 ALA 150 150 ?   ?   ?   B . n 
B 1 151 VAL 151 151 ?   ?   ?   B . n 
B 1 152 ASN 152 152 ?   ?   ?   B . n 
B 1 153 CYS 153 153 ?   ?   ?   B . n 
B 1 154 HIS 154 154 ?   ?   ?   B . n 
B 1 155 VAL 155 155 ?   ?   ?   B . n 
B 1 156 ILE 156 156 ?   ?   ?   B . n 
B 1 157 THR 157 157 ?   ?   ?   B . n 
B 1 158 TRP 158 158 ?   ?   ?   B . n 
B 1 159 GLU 159 159 159 GLU GLU B . n 
B 1 160 ARG 160 160 160 ARG ARG B . n 
B 1 161 ILE 161 161 161 ILE ILE B . n 
B 1 162 ILE 162 162 162 ILE ILE B . n 
B 1 163 SER 163 163 163 SER SER B . n 
B 1 164 HIS 164 164 164 HIS HIS B . n 
B 1 165 PHE 165 165 165 PHE PHE B . n 
B 1 166 ASP 166 166 166 ASP ASP B . n 
B 1 167 ILE 167 167 167 ILE ILE B . n 
B 1 168 PHE 168 168 168 PHE PHE B . n 
B 1 169 ALA 169 169 169 ALA ALA B . n 
B 1 170 PHE 170 170 170 PHE PHE B . n 
B 1 171 GLY 171 171 171 GLY GLY B . n 
B 1 172 HIS 172 172 172 HIS HIS B . n 
B 1 173 PHE 173 173 173 PHE PHE B . n 
B 1 174 TRP 174 174 174 TRP TRP B . n 
B 1 175 GLY 175 175 175 GLY GLY B . n 
B 1 176 TRP 176 176 176 TRP TRP B . n 
B 1 177 ALA 177 177 177 ALA ALA B . n 
B 1 178 MET 178 178 178 MET MET B . n 
B 1 179 LYS 179 179 179 LYS LYS B . n 
B 1 180 ALA 180 180 180 ALA ALA B . n 
B 1 181 LEU 181 181 181 LEU LEU B . n 
B 1 182 LEU 182 182 182 LEU LEU B . n 
B 1 183 ILE 183 183 183 ILE ILE B . n 
B 1 184 ARG 184 184 184 ARG ARG B . n 
B 1 185 SER 185 185 185 SER SER B . n 
B 1 186 TYR 186 186 186 TYR TYR B . n 
B 1 187 GLY 187 187 187 GLY GLY B . n 
B 1 188 LEU 188 188 188 LEU LEU B . n 
B 1 189 CYS 189 189 189 CYS CYS B . n 
B 1 190 TRP 190 190 190 TRP TRP B . n 
B 1 191 THR 191 191 191 THR THR B . n 
B 1 192 ILE 192 192 192 ILE ILE B . n 
B 1 193 SER 193 193 193 SER SER B . n 
B 1 194 ILE 194 194 194 ILE ILE B . n 
B 1 195 THR 195 195 195 THR THR B . n 
B 1 196 TRP 196 196 196 TRP TRP B . n 
B 1 197 GLU 197 197 197 GLU GLU B . n 
B 1 198 LEU 198 198 198 LEU LEU B . n 
B 1 199 THR 199 199 199 THR THR B . n 
B 1 200 GLU 200 200 200 GLU GLU B . n 
B 1 201 LEU 201 201 201 LEU LEU B . n 
B 1 202 PHE 202 202 202 PHE PHE B . n 
B 1 203 PHE 203 203 203 PHE PHE B . n 
B 1 204 MET 204 204 204 MET MET B . n 
B 1 205 HIS 205 205 205 HIS HIS B . n 
B 1 206 LEU 206 206 206 LEU LEU B . n 
B 1 207 LEU 207 207 207 LEU LEU B . n 
B 1 208 PRO 208 208 208 PRO PRO B . n 
B 1 209 ASN 209 209 209 ASN ASN B . n 
B 1 210 PHE 210 210 210 PHE PHE B . n 
B 1 211 ALA 211 211 211 ALA ALA B . n 
B 1 212 GLU 212 212 212 GLU GLU B . n 
B 1 213 CYS 213 213 213 CYS CYS B . n 
B 1 214 TRP 214 214 214 TRP TRP B . n 
B 1 215 TRP 215 215 215 TRP TRP B . n 
B 1 216 ASP 216 216 216 ASP ASP B . n 
B 1 217 GLN 217 217 217 GLN GLN B . n 
B 1 218 VAL 218 218 218 VAL VAL B . n 
B 1 219 ILE 219 219 219 ILE ILE B . n 
B 1 220 LEU 220 220 220 LEU LEU B . n 
B 1 221 ASP 221 221 221 ASP ASP B . n 
B 1 222 ILE 222 222 222 ILE ILE B . n 
B 1 223 LEU 223 223 223 LEU LEU B . n 
B 1 224 LEU 224 224 224 LEU LEU B . n 
B 1 225 CYS 225 225 225 CYS CYS B . n 
B 1 226 ASN 226 226 226 ASN ASN B . n 
B 1 227 GLY 227 227 227 GLY GLY B . n 
B 1 228 GLY 228 228 228 GLY GLY B . n 
B 1 229 GLY 229 229 229 GLY GLY B . n 
B 1 230 ILE 230 230 230 ILE ILE B . n 
B 1 231 TRP 231 231 231 TRP TRP B . n 
B 1 232 LEU 232 232 232 LEU LEU B . n 
B 1 233 GLY 233 233 233 GLY GLY B . n 
B 1 234 MET 234 234 234 MET MET B . n 
B 1 235 VAL 235 235 235 VAL VAL B . n 
B 1 236 VAL 236 236 236 VAL VAL B . n 
B 1 237 CYS 237 237 237 CYS CYS B . n 
B 1 238 ARG 238 238 238 ARG ARG B . n 
B 1 239 PHE 239 239 239 PHE PHE B . n 
B 1 240 LEU 240 240 240 LEU LEU B . n 
B 1 241 GLU 241 241 241 GLU GLU B . n 
B 1 242 MET 242 242 242 MET MET B . n 
B 1 243 ARG 243 243 243 ARG ARG B . n 
B 1 244 THR 244 244 244 THR THR B . n 
B 1 245 TYR 245 245 245 TYR TYR B . n 
B 1 246 HIS 246 246 246 HIS HIS B . n 
B 1 247 TRP 247 247 247 TRP TRP B . n 
B 1 248 ALA 248 248 248 ALA ALA B . n 
B 1 249 SER 249 249 249 SER SER B . n 
B 1 250 PHE 250 250 250 PHE PHE B . n 
B 1 251 LYS 251 251 251 LYS LYS B . n 
B 1 252 ASP 252 252 252 ASP ASP B . n 
B 1 253 ILE 253 253 253 ILE ILE B . n 
B 1 254 HIS 254 254 254 HIS HIS B . n 
B 1 255 THR 255 255 255 THR THR B . n 
B 1 256 THR 256 256 256 THR THR B . n 
B 1 257 THR 257 257 257 THR THR B . n 
B 1 258 GLY 258 258 258 GLY GLY B . n 
B 1 259 LYS 259 259 259 LYS LYS B . n 
B 1 260 ILE 260 260 260 ILE ILE B . n 
B 1 261 LYS 261 261 261 LYS LYS B . n 
B 1 262 ARG 262 262 262 ARG ARG B . n 
B 1 263 ALA 263 263 263 ALA ALA B . n 
B 1 264 VAL 264 264 264 VAL VAL B . n 
B 1 265 LEU 265 265 265 LEU LEU B . n 
B 1 266 GLN 266 266 266 GLN GLN B . n 
B 1 267 PHE 267 267 267 PHE PHE B . n 
B 1 268 THR 268 268 268 THR THR B . n 
B 1 269 PRO 269 269 269 PRO PRO B . n 
B 1 270 ALA 270 270 270 ALA ALA B . n 
B 1 271 SER 271 271 271 SER SER B . n 
B 1 272 TRP 272 272 272 TRP TRP B . n 
B 1 273 THR 273 273 273 THR THR B . n 
B 1 274 TYR 274 274 274 TYR TYR B . n 
B 1 275 VAL 275 275 275 VAL VAL B . n 
B 1 276 ARG 276 276 276 ARG ARG B . n 
B 1 277 TRP 277 277 277 TRP TRP B . n 
B 1 278 PHE 278 278 278 PHE PHE B . n 
B 1 279 ASP 279 279 279 ASP ASP B . n 
B 1 280 PRO 280 280 280 PRO PRO B . n 
B 1 281 LYS 281 281 281 LYS LYS B . n 
B 1 282 SER 282 282 282 SER SER B . n 
B 1 283 SER 283 283 283 SER SER B . n 
B 1 284 PHE 284 284 284 PHE PHE B . n 
B 1 285 GLN 285 285 285 GLN GLN B . n 
B 1 286 ARG 286 286 286 ARG ARG B . n 
B 1 287 VAL 287 287 287 VAL VAL B . n 
B 1 288 ALA 288 288 288 ALA ALA B . n 
B 1 289 GLY 289 289 289 GLY GLY B . n 
B 1 290 VAL 290 290 290 VAL VAL B . n 
B 1 291 TYR 291 291 291 TYR TYR B . n 
B 1 292 LEU 292 292 292 LEU LEU B . n 
B 1 293 PHE 293 293 293 PHE PHE B . n 
B 1 294 MET 294 294 294 MET MET B . n 
B 1 295 ILE 295 295 295 ILE ILE B . n 
B 1 296 ILE 296 296 296 ILE ILE B . n 
B 1 297 TRP 297 297 297 TRP TRP B . n 
B 1 298 GLN 298 298 298 GLN GLN B . n 
B 1 299 LEU 299 299 299 LEU LEU B . n 
B 1 300 THR 300 300 300 THR THR B . n 
B 1 301 GLU 301 301 301 GLU GLU B . n 
B 1 302 LEU 302 302 302 LEU LEU B . n 
B 1 303 ASN 303 303 303 ASN ASN B . n 
B 1 304 THR 304 304 304 THR THR B . n 
B 1 305 PHE 305 305 305 PHE PHE B . n 
B 1 306 PHE 306 306 306 PHE PHE B . n 
B 1 307 LEU 307 307 307 LEU LEU B . n 
B 1 308 LYS 308 308 308 LYS LYS B . n 
B 1 309 HIS 309 309 309 HIS HIS B . n 
B 1 310 ILE 310 310 310 ILE ILE B . n 
B 1 311 PHE 311 311 311 PHE PHE B . n 
B 1 312 VAL 312 312 312 VAL VAL B . n 
B 1 313 PHE 313 313 313 PHE PHE B . n 
B 1 314 GLN 314 314 314 GLN GLN B . n 
B 1 315 ALA 315 315 315 ALA ALA B . n 
B 1 316 SER 316 316 316 SER SER B . n 
B 1 317 HIS 317 317 317 HIS HIS B . n 
B 1 318 PRO 318 318 318 PRO PRO B . n 
B 1 319 LEU 319 319 319 LEU LEU B . n 
B 1 320 SER 320 320 320 SER SER B . n 
B 1 321 TRP 321 321 321 TRP TRP B . n 
B 1 322 GLY 322 322 322 GLY GLY B . n 
B 1 323 ARG 323 323 323 ARG ARG B . n 
B 1 324 ILE 324 324 324 ILE ILE B . n 
B 1 325 LEU 325 325 325 LEU LEU B . n 
B 1 326 PHE 326 326 326 PHE PHE B . n 
B 1 327 ILE 327 327 327 ILE ILE B . n 
B 1 328 GLY 328 328 328 GLY GLY B . n 
B 1 329 GLY 329 329 329 GLY GLY B . n 
B 1 330 ILE 330 330 330 ILE ILE B . n 
B 1 331 THR 331 331 331 THR THR B . n 
B 1 332 ALA 332 332 332 ALA ALA B . n 
B 1 333 PRO 333 333 333 PRO PRO B . n 
B 1 334 THR 334 334 334 THR THR B . n 
B 1 335 VAL 335 335 335 VAL VAL B . n 
B 1 336 ARG 336 336 336 ARG ARG B . n 
B 1 337 GLN 337 337 337 GLN GLN B . n 
B 1 338 TYR 338 338 338 TYR TYR B . n 
B 1 339 TYR 339 339 339 TYR TYR B . n 
B 1 340 ALA 340 340 340 ALA ALA B . n 
B 1 341 TYR 341 341 341 TYR TYR B . n 
B 1 342 LEU 342 342 342 LEU LEU B . n 
B 1 343 THR 343 343 343 THR THR B . n 
B 1 344 ASP 344 344 344 ASP ASP B . n 
B 1 345 THR 345 345 345 THR THR B . n 
B 1 346 GLN 346 346 346 GLN GLN B . n 
B 1 347 CYS 347 347 347 CYS CYS B . n 
B 1 348 LYS 348 348 348 LYS LYS B . n 
B 1 349 ARG 349 349 349 ARG ARG B . n 
B 1 350 VAL 350 350 350 VAL VAL B . n 
B 1 351 GLY 351 351 351 GLY GLY B . n 
B 1 352 THR 352 352 352 THR THR B . n 
B 1 353 GLN 353 353 353 GLN GLN B . n 
B 1 354 CYS 354 354 354 CYS CYS B . n 
B 1 355 TRP 355 355 355 TRP TRP B . n 
B 1 356 VAL 356 356 356 VAL VAL B . n 
B 1 357 PHE 357 357 357 PHE PHE B . n 
B 1 358 GLY 358 358 358 GLY GLY B . n 
B 1 359 VAL 359 359 359 VAL VAL B . n 
B 1 360 ILE 360 360 360 ILE ILE B . n 
B 1 361 GLY 361 361 361 GLY GLY B . n 
B 1 362 PHE 362 362 362 PHE PHE B . n 
B 1 363 LEU 363 363 363 LEU LEU B . n 
B 1 364 GLU 364 364 364 GLU GLU B . n 
B 1 365 ALA 365 365 365 ALA ALA B . n 
B 1 366 ILE 366 366 366 ILE ILE B . n 
B 1 367 VAL 367 367 367 VAL VAL B . n 
B 1 368 CYS 368 368 368 CYS CYS B . n 
B 1 369 ILE 369 369 369 ILE ILE B . n 
B 1 370 LYS 370 370 370 LYS LYS B . n 
B 1 371 PHE 371 371 371 PHE PHE B . n 
B 1 372 GLY 372 372 372 GLY GLY B . n 
B 1 373 GLN 373 373 373 GLN GLN B . n 
B 1 374 ASP 374 374 374 ASP ASP B . n 
B 1 375 LEU 375 375 375 LEU LEU B . n 
B 1 376 PHE 376 376 376 PHE PHE B . n 
B 1 377 SER 377 377 377 SER SER B . n 
B 1 378 LYS 378 378 378 LYS LYS B . n 
B 1 379 THR 379 379 379 THR THR B . n 
B 1 380 GLN 380 380 380 GLN GLN B . n 
B 1 381 ILE 381 381 381 ILE ILE B . n 
B 1 382 LEU 382 382 382 LEU LEU B . n 
B 1 383 TYR 383 383 383 TYR TYR B . n 
B 1 384 VAL 384 384 384 VAL VAL B . n 
B 1 385 VAL 385 385 385 VAL VAL B . n 
B 1 386 LEU 386 386 386 LEU LEU B . n 
B 1 387 TRP 387 387 387 TRP TRP B . n 
B 1 388 LEU 388 388 388 LEU LEU B . n 
B 1 389 LEU 389 389 389 LEU LEU B . n 
B 1 390 CYS 390 390 390 CYS CYS B . n 
B 1 391 VAL 391 391 391 VAL VAL B . n 
B 1 392 ALA 392 392 392 ALA ALA B . n 
B 1 393 PHE 393 393 393 PHE PHE B . n 
B 1 394 THR 394 394 394 THR THR B . n 
B 1 395 THR 395 395 395 THR THR B . n 
B 1 396 PHE 396 396 396 PHE PHE B . n 
B 1 397 LEU 397 397 397 LEU LEU B . n 
B 1 398 CYS 398 398 398 CYS CYS B . n 
B 1 399 LEU 399 399 399 LEU LEU B . n 
B 1 400 TYR 400 400 400 TYR TYR B . n 
B 1 401 GLY 401 401 401 GLY GLY B . n 
B 1 402 MET 402 402 402 MET MET B . n 
B 1 403 ILE 403 403 403 ILE ILE B . n 
B 1 404 TRP 404 404 404 TRP TRP B . n 
B 1 405 TYR 405 405 405 TYR TYR B . n 
B 1 406 ALA 406 406 406 ALA ALA B . n 
B 1 407 GLU 407 407 407 GLU GLU B . n 
B 1 408 HIS 408 408 408 HIS HIS B . n 
B 1 409 TYR 409 409 ?   ?   ?   B . n 
B 1 410 GLY 410 410 ?   ?   ?   B . n 
B 1 411 HIS 411 411 ?   ?   ?   B . n 
B 1 412 ARG 412 412 ?   ?   ?   B . n 
B 1 413 GLU 413 413 ?   ?   ?   B . n 
B 1 414 LYS 414 414 ?   ?   ?   B . n 
B 1 415 THR 415 415 ?   ?   ?   B . n 
B 1 416 TYR 416 416 ?   ?   ?   B . n 
B 1 417 SER 417 417 ?   ?   ?   B . n 
B 1 418 GLU 418 418 ?   ?   ?   B . n 
B 1 419 CYS 419 419 ?   ?   ?   B . n 
B 1 420 GLU 420 420 ?   ?   ?   B . n 
B 1 421 ASP 421 421 ?   ?   ?   B . n 
B 1 422 GLY 422 422 ?   ?   ?   B . n 
B 1 423 THR 423 423 ?   ?   ?   B . n 
B 1 424 TYR 424 424 ?   ?   ?   B . n 
B 1 425 SER 425 425 ?   ?   ?   B . n 
B 1 426 PRO 426 426 ?   ?   ?   B . n 
B 1 427 GLU 427 427 ?   ?   ?   B . n 
B 1 428 ILE 428 428 ?   ?   ?   B . n 
B 1 429 SER 429 429 ?   ?   ?   B . n 
B 1 430 TRP 430 430 ?   ?   ?   B . n 
B 1 431 HIS 431 431 ?   ?   ?   B . n 
B 1 432 HIS 432 432 ?   ?   ?   B . n 
B 1 433 ARG 433 433 ?   ?   ?   B . n 
B 1 434 LYS 434 434 ?   ?   ?   B . n 
B 1 435 GLY 435 435 ?   ?   ?   B . n 
B 1 436 THR 436 436 ?   ?   ?   B . n 
B 1 437 LYS 437 437 ?   ?   ?   B . n 
B 1 438 GLY 438 438 ?   ?   ?   B . n 
B 1 439 SER 439 439 ?   ?   ?   B . n 
B 1 440 GLU 440 440 ?   ?   ?   B . n 
B 1 441 ASP 441 441 ?   ?   ?   B . n 
B 1 442 SER 442 442 ?   ?   ?   B . n 
B 1 443 PRO 443 443 ?   ?   ?   B . n 
B 1 444 PRO 444 444 ?   ?   ?   B . n 
B 1 445 LYS 445 445 ?   ?   ?   B . n 
B 1 446 HIS 446 446 ?   ?   ?   B . n 
B 1 447 ALA 447 447 ?   ?   ?   B . n 
B 1 448 GLY 448 448 ?   ?   ?   B . n 
B 1 449 ASN 449 449 ?   ?   ?   B . n 
B 1 450 ASN 450 450 ?   ?   ?   B . n 
B 1 451 GLU 451 451 ?   ?   ?   B . n 
B 1 452 SER 452 452 ?   ?   ?   B . n 
B 1 453 HIS 453 453 ?   ?   ?   B . n 
B 1 454 SER 454 454 ?   ?   ?   B . n 
B 1 455 SER 455 455 ?   ?   ?   B . n 
B 1 456 ARG 456 456 ?   ?   ?   B . n 
B 1 457 ARG 457 457 ?   ?   ?   B . n 
B 1 458 ARG 458 458 ?   ?   ?   B . n 
B 1 459 ASN 459 459 ?   ?   ?   B . n 
B 1 460 ARG 460 460 ?   ?   ?   B . n 
B 1 461 HIS 461 461 ?   ?   ?   B . n 
B 1 462 SER 462 462 ?   ?   ?   B . n 
B 1 463 LYS 463 463 ?   ?   ?   B . n 
B 1 464 SER 464 464 ?   ?   ?   B . n 
B 1 465 LYS 465 465 ?   ?   ?   B . n 
B 1 466 VAL 466 466 ?   ?   ?   B . n 
B 1 467 THR 467 467 ?   ?   ?   B . n 
B 1 468 ASN 468 468 ?   ?   ?   B . n 
B 1 469 GLY 469 469 ?   ?   ?   B . n 
B 1 470 VAL 470 470 ?   ?   ?   B . n 
B 1 471 GLY 471 471 ?   ?   ?   B . n 
B 1 472 LYS 472 472 ?   ?   ?   B . n 
B 1 473 LYS 473 473 ?   ?   ?   B . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 LBN ? ? LBN ? ? 'SUBJECT OF INVESTIGATION' ? 
2 PSF ? ? PSF ? ? 'SUBJECT OF INVESTIGATION' ? 
3 T7X ? ? T7X ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 PSF 1 501 502 PSF PSF A . 
D 2 PSF 1 502 503 PSF PSF A . 
E 3 LBN 1 503 505 LBN LBN A . 
F 3 LBN 1 504 507 LBN LBN A . 
G 4 D12 1 505 508 D12 D12 A . 
H 5 C14 1 506 509 C14 C14 A . 
I 3 LBN 1 507 510 LBN LBN A . 
J 3 LBN 1 508 511 LBN LBN A . 
K 3 LBN 1 509 512 LBN LBN A . 
L 6 T7X 1 510 504 T7X T7X A . 
M 3 LBN 1 511 511 LBN LBN A . 
N 6 T7X 1 501 504 T7X T7X B . 
O 2 PSF 1 502 502 PSF PSF B . 
P 2 PSF 1 503 503 PSF PSF B . 
Q 3 LBN 1 504 505 LBN LBN B . 
R 3 LBN 1 505 507 LBN LBN B . 
S 4 D12 1 506 508 D12 D12 B . 
T 5 C14 1 507 509 C14 C14 B . 
U 3 LBN 1 508 510 LBN LBN B . 
V 3 LBN 1 509 512 LBN LBN B . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 N 1 A LBN 504 ? C4  ? F LBN 1 C4  
2  1 N 1 A LBN 504 ? C5  ? F LBN 1 C5  
3  1 N 1 A LBN 504 ? C7  ? F LBN 1 C7  
4  1 N 1 A LBN 504 ? C8  ? F LBN 1 C8  
5  1 N 1 A LBN 504 ? C10 ? F LBN 1 C10 
6  1 N 1 A LBN 504 ? C11 ? F LBN 1 C11 
7  1 N 1 A LBN 504 ? C13 ? F LBN 1 C13 
8  1 N 1 A LBN 504 ? C14 ? F LBN 1 C14 
9  1 N 1 A LBN 504 ? C16 ? F LBN 1 C16 
10 1 N 1 A LBN 504 ? C17 ? F LBN 1 C17 
11 1 N 1 A LBN 504 ? C19 ? F LBN 1 C19 
12 1 N 1 A LBN 504 ? C20 ? F LBN 1 C20 
13 1 N 1 A LBN 504 ? C21 ? F LBN 1 C21 
14 1 N 1 A LBN 504 ? C22 ? F LBN 1 C22 
15 1 N 1 A LBN 504 ? C23 ? F LBN 1 C23 
16 1 N 1 A LBN 504 ? C24 ? F LBN 1 C24 
17 1 N 1 A LBN 504 ? C31 ? F LBN 1 C31 
18 1 N 1 A LBN 504 ? C32 ? F LBN 1 C32 
19 1 N 1 A LBN 504 ? C33 ? F LBN 1 C33 
20 1 N 1 A LBN 504 ? C42 ? F LBN 1 C42 
21 1 N 1 A LBN 508 ? C5  ? J LBN 1 C5  
22 1 N 1 A LBN 508 ? C8  ? J LBN 1 C8  
23 1 N 1 A LBN 508 ? C11 ? J LBN 1 C11 
24 1 N 1 A LBN 508 ? C14 ? J LBN 1 C14 
25 1 N 1 A LBN 508 ? C17 ? J LBN 1 C17 
26 1 N 1 A LBN 508 ? C20 ? J LBN 1 C20 
27 1 N 1 A LBN 508 ? C22 ? J LBN 1 C22 
28 1 N 1 A LBN 508 ? C23 ? J LBN 1 C23 
29 1 N 1 A LBN 508 ? C24 ? J LBN 1 C24 
30 1 N 1 A LBN 508 ? C38 ? J LBN 1 C38 
31 1 N 1 A LBN 508 ? C39 ? J LBN 1 C39 
32 1 N 1 A LBN 508 ? C40 ? J LBN 1 C40 
33 1 N 1 A LBN 508 ? C41 ? J LBN 1 C41 
34 1 N 1 A LBN 508 ? C42 ? J LBN 1 C42 
35 1 N 1 A T7X 510 ? C39 ? L T7X 1 C39 
36 1 N 1 A T7X 510 ? C40 ? L T7X 1 C40 
37 1 N 1 A T7X 510 ? C41 ? L T7X 1 C41 
38 1 N 1 A T7X 510 ? C29 ? L T7X 1 C29 
39 1 N 1 A T7X 510 ? C30 ? L T7X 1 C30 
40 1 N 1 A T7X 510 ? C42 ? L T7X 1 C42 
41 1 N 1 A T7X 510 ? C43 ? L T7X 1 C43 
42 1 N 1 A T7X 510 ? C44 ? L T7X 1 C44 
43 1 N 1 A T7X 510 ? C45 ? L T7X 1 C45 
44 1 N 1 A T7X 510 ? C46 ? L T7X 1 C46 
45 1 N 1 A T7X 510 ? C47 ? L T7X 1 C47 
46 1 N 1 A LBN 511 ? C5  ? M LBN 1 C5  
47 1 N 1 A LBN 511 ? C8  ? M LBN 1 C8  
48 1 N 1 A LBN 511 ? C11 ? M LBN 1 C11 
49 1 N 1 A LBN 511 ? C14 ? M LBN 1 C14 
50 1 N 1 A LBN 511 ? C17 ? M LBN 1 C17 
51 1 N 1 A LBN 511 ? C20 ? M LBN 1 C20 
52 1 N 1 A LBN 511 ? C22 ? M LBN 1 C22 
53 1 N 1 A LBN 511 ? C23 ? M LBN 1 C23 
54 1 N 1 A LBN 511 ? C24 ? M LBN 1 C24 
55 1 N 1 A LBN 511 ? C38 ? M LBN 1 C38 
56 1 N 1 A LBN 511 ? C39 ? M LBN 1 C39 
57 1 N 1 A LBN 511 ? C40 ? M LBN 1 C40 
58 1 N 1 A LBN 511 ? C41 ? M LBN 1 C41 
59 1 N 1 A LBN 511 ? C42 ? M LBN 1 C42 
60 1 N 1 B T7X 501 ? C39 ? N T7X 1 C39 
61 1 N 1 B T7X 501 ? C40 ? N T7X 1 C40 
62 1 N 1 B T7X 501 ? C41 ? N T7X 1 C41 
63 1 N 1 B T7X 501 ? C29 ? N T7X 1 C29 
64 1 N 1 B T7X 501 ? C30 ? N T7X 1 C30 
65 1 N 1 B T7X 501 ? C42 ? N T7X 1 C42 
66 1 N 1 B T7X 501 ? C43 ? N T7X 1 C43 
67 1 N 1 B T7X 501 ? C44 ? N T7X 1 C44 
68 1 N 1 B T7X 501 ? C45 ? N T7X 1 C45 
69 1 N 1 B T7X 501 ? C46 ? N T7X 1 C46 
70 1 N 1 B T7X 501 ? C47 ? N T7X 1 C47 
71 1 N 1 B LBN 505 ? C4  ? R LBN 1 C4  
72 1 N 1 B LBN 505 ? C5  ? R LBN 1 C5  
73 1 N 1 B LBN 505 ? C7  ? R LBN 1 C7  
74 1 N 1 B LBN 505 ? C8  ? R LBN 1 C8  
75 1 N 1 B LBN 505 ? C10 ? R LBN 1 C10 
76 1 N 1 B LBN 505 ? C11 ? R LBN 1 C11 
77 1 N 1 B LBN 505 ? C13 ? R LBN 1 C13 
78 1 N 1 B LBN 505 ? C14 ? R LBN 1 C14 
79 1 N 1 B LBN 505 ? C16 ? R LBN 1 C16 
80 1 N 1 B LBN 505 ? C17 ? R LBN 1 C17 
81 1 N 1 B LBN 505 ? C19 ? R LBN 1 C19 
82 1 N 1 B LBN 505 ? C20 ? R LBN 1 C20 
83 1 N 1 B LBN 505 ? C21 ? R LBN 1 C21 
84 1 N 1 B LBN 505 ? C22 ? R LBN 1 C22 
85 1 N 1 B LBN 505 ? C23 ? R LBN 1 C23 
86 1 N 1 B LBN 505 ? C24 ? R LBN 1 C24 
87 1 N 1 B LBN 505 ? C31 ? R LBN 1 C31 
88 1 N 1 B LBN 505 ? C32 ? R LBN 1 C32 
89 1 N 1 B LBN 505 ? C33 ? R LBN 1 C33 
90 1 N 1 B LBN 505 ? C42 ? R LBN 1 C42 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9KQF 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9KQF 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9KQF 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9KQF 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            3.25 
_refine.ls_d_res_low                             ? 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'REAL-SPACE (WEIGHTED MAP SUM AT ATOM CENTERS)' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.005  ? 7276 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.599  ? 9782 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 19.102 ? 1244 ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.042  ? 1002 ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.004  ? 1126 ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9KQF 
_struct.title                        'Cryo-EM structure of PSS1 in the absence of calcium or L-serine' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9KQF 
_struct_keywords.text            
'phosphatidylserine synthase, ER membrane protein, integral membrane protein, transmembrane enzyme, PS, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 2 ? 
E N N 3 ? 
F N N 3 ? 
G N N 4 ? 
H N N 5 ? 
I N N 3 ? 
J N N 3 ? 
K N N 3 ? 
L N N 6 ? 
M N N 3 ? 
N N N 6 ? 
O N N 2 ? 
P N N 2 ? 
Q N N 3 ? 
R N N 3 ? 
S N N 4 ? 
T N N 5 ? 
U N N 3 ? 
V N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    PTSS1_HUMAN 
_struct_ref.pdbx_db_accession          P48651 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MASCVGSRTLSKDDVNYKMHFRMINEQQVEDITIDFFYRPHTITLLSFTIVSLMYFAFTRDDSVPEDNIWRGILSVIFFF
LIISVLAFPNGPFTRPHPALWRMVFGLSVLYFLFLVFLLFLNFEQVKSLMYWLDPNLRYATREADVMEYAVNCHVITWER
IISHFDIFAFGHFWGWAMKALLIRSYGLCWTISITWELTELFFMHLLPNFAECWWDQVILDILLCNGGGIWLGMVVCRFL
EMRTYHWASFKDIHTTTGKIKRAVLQFTPASWTYVRWFDPKSSFQRVAGVYLFMIIWQLTELNTFFLKHIFVFQASHPLS
WGRILFIGGITAPTVRQYYAYLTDTQCKRVGTQCWVFGVIGFLEAIVCIKFGQDLFSKTQILYVVLWLLCVAFTTFLCLY
GMIWYAEHYGHREKTYSECEDGTYSPEISWHHRKGTKGSEDSPPKHAGNNESHSSRRRNRHSKSKVTNGVGKK
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9KQF A 1 ? 473 ? P48651 1 ? 473 ? 1 473 
2 1 9KQF B 1 ? 473 ? P48651 1 ? 473 ? 1 473 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ASP A 14  ? GLU A 26  ? ASP A 14  GLU A 26  1 ? 13 
HELX_P HELX_P2  AA2 ILE A 34  ? TYR A 38  ? ILE A 34  TYR A 38  5 ? 5  
HELX_P HELX_P3  AA3 HIS A 41  ? THR A 59  ? HIS A 41  THR A 59  1 ? 19 
HELX_P HELX_P4  AA4 VAL A 64  ? PHE A 88  ? VAL A 64  PHE A 88  1 ? 25 
HELX_P HELX_P5  AA5 HIS A 97  ? LEU A 119 ? HIS A 97  LEU A 119 1 ? 23 
HELX_P HELX_P6  AA6 ASN A 122 ? ASP A 134 ? ASN A 122 ASP A 134 1 ? 13 
HELX_P HELX_P7  AA7 PRO A 135 ? ARG A 138 ? PRO A 135 ARG A 138 5 ? 4  
HELX_P HELX_P8  AA8 ARG A 160 ? PHE A 165 ? ARG A 160 PHE A 165 1 ? 6  
HELX_P HELX_P9  AA9 ASP A 166 ? ARG A 184 ? ASP A 166 ARG A 184 1 ? 19 
HELX_P HELX_P10 AB1 SER A 185 ? PHE A 203 ? SER A 185 PHE A 203 1 ? 19 
HELX_P HELX_P11 AB2 MET A 204 ? LEU A 206 ? MET A 204 LEU A 206 5 ? 3  
HELX_P HELX_P12 AB3 VAL A 218 ? LEU A 223 ? VAL A 218 LEU A 223 1 ? 6  
HELX_P HELX_P13 AB4 LEU A 224 ? ARG A 243 ? LEU A 224 ARG A 243 1 ? 20 
HELX_P HELX_P14 AB5 THR A 255 ? PHE A 267 ? THR A 255 PHE A 267 1 ? 13 
HELX_P HELX_P15 AB6 SER A 283 ? VAL A 312 ? SER A 283 VAL A 312 1 ? 30 
HELX_P HELX_P16 AB7 HIS A 317 ? ASP A 344 ? HIS A 317 ASP A 344 1 ? 28 
HELX_P HELX_P17 AB8 GLY A 351 ? GLY A 372 ? GLY A 351 GLY A 372 1 ? 22 
HELX_P HELX_P18 AB9 ILE A 381 ? HIS A 408 ? ILE A 381 HIS A 408 1 ? 28 
HELX_P HELX_P19 AC1 VAL B 15  ? GLU B 26  ? VAL B 15  GLU B 26  1 ? 12 
HELX_P HELX_P20 AC2 ILE B 34  ? TYR B 38  ? ILE B 34  TYR B 38  5 ? 5  
HELX_P HELX_P21 AC3 ILE B 43  ? THR B 59  ? ILE B 43  THR B 59  1 ? 17 
HELX_P HELX_P22 AC4 VAL B 64  ? PHE B 88  ? VAL B 64  PHE B 88  1 ? 25 
HELX_P HELX_P23 AC5 HIS B 97  ? LEU B 119 ? HIS B 97  LEU B 119 1 ? 23 
HELX_P HELX_P24 AC6 ASN B 122 ? ASP B 134 ? ASN B 122 ASP B 134 1 ? 13 
HELX_P HELX_P25 AC7 PRO B 135 ? ARG B 138 ? PRO B 135 ARG B 138 5 ? 4  
HELX_P HELX_P26 AC8 ARG B 160 ? PHE B 165 ? ARG B 160 PHE B 165 1 ? 6  
HELX_P HELX_P27 AC9 ASP B 166 ? ARG B 184 ? ASP B 166 ARG B 184 1 ? 19 
HELX_P HELX_P28 AD1 SER B 185 ? PHE B 203 ? SER B 185 PHE B 203 1 ? 19 
HELX_P HELX_P29 AD2 MET B 204 ? LEU B 206 ? MET B 204 LEU B 206 5 ? 3  
HELX_P HELX_P30 AD3 CYS B 213 ? GLN B 217 ? CYS B 213 GLN B 217 5 ? 5  
HELX_P HELX_P31 AD4 LEU B 224 ? MET B 242 ? LEU B 224 MET B 242 1 ? 19 
HELX_P HELX_P32 AD5 THR B 255 ? PHE B 267 ? THR B 255 PHE B 267 1 ? 13 
HELX_P HELX_P33 AD6 SER B 283 ? PHE B 311 ? SER B 283 PHE B 311 1 ? 29 
HELX_P HELX_P34 AD7 HIS B 317 ? ASP B 344 ? HIS B 317 ASP B 344 1 ? 28 
HELX_P HELX_P35 AD8 GLY B 351 ? GLY B 372 ? GLY B 351 GLY B 372 1 ? 22 
HELX_P HELX_P36 AD9 ILE B 381 ? HIS B 408 ? ILE B 381 HIS B 408 1 ? 28 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 ARG 95 A . ? ARG 95 A PRO 96 A ? PRO 96 A 1 -1.52 
2 ARG 95 B . ? ARG 95 B PRO 96 B ? PRO 96 B 1 -1.39 
# 
_pdbx_entry_details.entry_id                   9KQF 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1  1 O   A CYS 347 ? ? C15 A LBN 507 ? ? 1.37 
2  1 O   B CYS 347 ? ? C15 B LBN 508 ? ? 1.38 
3  1 C21 A LBN 503 ? ? C21 B LBN 504 ? ? 1.49 
4  1 CD1 B LEU 388 ? ? C14 B LBN 508 ? ? 1.49 
5  1 CZ3 A TRP 297 ? ? C21 A LBN 507 ? ? 1.49 
6  1 CD1 A LEU 388 ? ? C14 A LBN 507 ? ? 1.49 
7  1 C16 A LBN 509 ? ? C24 B LBN 504 ? ? 1.49 
8  1 CE3 A TRP 297 ? ? C21 A LBN 507 ? ? 1.69 
9  1 C19 A LBN 503 ? ? C21 B LBN 504 ? ? 1.76 
10 1 C13 A LBN 509 ? ? C24 B LBN 504 ? ? 1.86 
11 1 C21 A LBN 503 ? ? C19 B LBN 504 ? ? 1.98 
12 1 O   B LEU 265 ? ? OG1 B THR 268 ? ? 2.18 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 SER A 185 ? ? -162.59 119.57 
2 1 VAL A 218 ? ? -106.43 -64.75 
3 1 ASP A 221 ? ? -95.43  -61.93 
4 1 LEU A 224 ? ? -93.83  -63.09 
5 1 VAL A 312 ? ? 38.51   65.00  
6 1 SER A 320 ? ? -98.55  -60.41 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9KQF 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9KQF 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.25 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               109125 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'cryoEM structure of PSS1 dimer' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9KQF 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9KQF 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9KQF 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1   ? A MET 1   
2   1 Y 1 A ALA 2   ? A ALA 2   
3   1 Y 1 A SER 3   ? A SER 3   
4   1 Y 1 A CYS 4   ? A CYS 4   
5   1 Y 1 A VAL 5   ? A VAL 5   
6   1 Y 1 A GLY 6   ? A GLY 6   
7   1 Y 1 A SER 7   ? A SER 7   
8   1 Y 1 A ARG 8   ? A ARG 8   
9   1 Y 1 A THR 9   ? A THR 9   
10  1 Y 1 A LEU 10  ? A LEU 10  
11  1 Y 1 A SER 11  ? A SER 11  
12  1 Y 1 A LYS 12  ? A LYS 12  
13  1 Y 1 A ASP 13  ? A ASP 13  
14  1 Y 1 A THR 141 ? A THR 141 
15  1 Y 1 A ARG 142 ? A ARG 142 
16  1 Y 1 A GLU 143 ? A GLU 143 
17  1 Y 1 A ALA 144 ? A ALA 144 
18  1 Y 1 A ASP 145 ? A ASP 145 
19  1 Y 1 A VAL 146 ? A VAL 146 
20  1 Y 1 A MET 147 ? A MET 147 
21  1 Y 1 A GLU 148 ? A GLU 148 
22  1 Y 1 A TYR 149 ? A TYR 149 
23  1 Y 1 A ALA 150 ? A ALA 150 
24  1 Y 1 A VAL 151 ? A VAL 151 
25  1 Y 1 A ASN 152 ? A ASN 152 
26  1 Y 1 A CYS 153 ? A CYS 153 
27  1 Y 1 A HIS 154 ? A HIS 154 
28  1 Y 1 A VAL 155 ? A VAL 155 
29  1 Y 1 A ILE 156 ? A ILE 156 
30  1 Y 1 A THR 157 ? A THR 157 
31  1 Y 1 A TRP 158 ? A TRP 158 
32  1 Y 1 A TYR 409 ? A TYR 409 
33  1 Y 1 A GLY 410 ? A GLY 410 
34  1 Y 1 A HIS 411 ? A HIS 411 
35  1 Y 1 A ARG 412 ? A ARG 412 
36  1 Y 1 A GLU 413 ? A GLU 413 
37  1 Y 1 A LYS 414 ? A LYS 414 
38  1 Y 1 A THR 415 ? A THR 415 
39  1 Y 1 A TYR 416 ? A TYR 416 
40  1 Y 1 A SER 417 ? A SER 417 
41  1 Y 1 A GLU 418 ? A GLU 418 
42  1 Y 1 A CYS 419 ? A CYS 419 
43  1 Y 1 A GLU 420 ? A GLU 420 
44  1 Y 1 A ASP 421 ? A ASP 421 
45  1 Y 1 A GLY 422 ? A GLY 422 
46  1 Y 1 A THR 423 ? A THR 423 
47  1 Y 1 A TYR 424 ? A TYR 424 
48  1 Y 1 A SER 425 ? A SER 425 
49  1 Y 1 A PRO 426 ? A PRO 426 
50  1 Y 1 A GLU 427 ? A GLU 427 
51  1 Y 1 A ILE 428 ? A ILE 428 
52  1 Y 1 A SER 429 ? A SER 429 
53  1 Y 1 A TRP 430 ? A TRP 430 
54  1 Y 1 A HIS 431 ? A HIS 431 
55  1 Y 1 A HIS 432 ? A HIS 432 
56  1 Y 1 A ARG 433 ? A ARG 433 
57  1 Y 1 A LYS 434 ? A LYS 434 
58  1 Y 1 A GLY 435 ? A GLY 435 
59  1 Y 1 A THR 436 ? A THR 436 
60  1 Y 1 A LYS 437 ? A LYS 437 
61  1 Y 1 A GLY 438 ? A GLY 438 
62  1 Y 1 A SER 439 ? A SER 439 
63  1 Y 1 A GLU 440 ? A GLU 440 
64  1 Y 1 A ASP 441 ? A ASP 441 
65  1 Y 1 A SER 442 ? A SER 442 
66  1 Y 1 A PRO 443 ? A PRO 443 
67  1 Y 1 A PRO 444 ? A PRO 444 
68  1 Y 1 A LYS 445 ? A LYS 445 
69  1 Y 1 A HIS 446 ? A HIS 446 
70  1 Y 1 A ALA 447 ? A ALA 447 
71  1 Y 1 A GLY 448 ? A GLY 448 
72  1 Y 1 A ASN 449 ? A ASN 449 
73  1 Y 1 A ASN 450 ? A ASN 450 
74  1 Y 1 A GLU 451 ? A GLU 451 
75  1 Y 1 A SER 452 ? A SER 452 
76  1 Y 1 A HIS 453 ? A HIS 453 
77  1 Y 1 A SER 454 ? A SER 454 
78  1 Y 1 A SER 455 ? A SER 455 
79  1 Y 1 A ARG 456 ? A ARG 456 
80  1 Y 1 A ARG 457 ? A ARG 457 
81  1 Y 1 A ARG 458 ? A ARG 458 
82  1 Y 1 A ASN 459 ? A ASN 459 
83  1 Y 1 A ARG 460 ? A ARG 460 
84  1 Y 1 A HIS 461 ? A HIS 461 
85  1 Y 1 A SER 462 ? A SER 462 
86  1 Y 1 A LYS 463 ? A LYS 463 
87  1 Y 1 A SER 464 ? A SER 464 
88  1 Y 1 A LYS 465 ? A LYS 465 
89  1 Y 1 A VAL 466 ? A VAL 466 
90  1 Y 1 A THR 467 ? A THR 467 
91  1 Y 1 A ASN 468 ? A ASN 468 
92  1 Y 1 A GLY 469 ? A GLY 469 
93  1 Y 1 A VAL 470 ? A VAL 470 
94  1 Y 1 A GLY 471 ? A GLY 471 
95  1 Y 1 A LYS 472 ? A LYS 472 
96  1 Y 1 A LYS 473 ? A LYS 473 
97  1 Y 1 B MET 1   ? B MET 1   
98  1 Y 1 B ALA 2   ? B ALA 2   
99  1 Y 1 B SER 3   ? B SER 3   
100 1 Y 1 B CYS 4   ? B CYS 4   
101 1 Y 1 B VAL 5   ? B VAL 5   
102 1 Y 1 B GLY 6   ? B GLY 6   
103 1 Y 1 B SER 7   ? B SER 7   
104 1 Y 1 B ARG 8   ? B ARG 8   
105 1 Y 1 B THR 9   ? B THR 9   
106 1 Y 1 B LEU 10  ? B LEU 10  
107 1 Y 1 B SER 11  ? B SER 11  
108 1 Y 1 B LYS 12  ? B LYS 12  
109 1 Y 1 B ASP 13  ? B ASP 13  
110 1 Y 1 B THR 141 ? B THR 141 
111 1 Y 1 B ARG 142 ? B ARG 142 
112 1 Y 1 B GLU 143 ? B GLU 143 
113 1 Y 1 B ALA 144 ? B ALA 144 
114 1 Y 1 B ASP 145 ? B ASP 145 
115 1 Y 1 B VAL 146 ? B VAL 146 
116 1 Y 1 B MET 147 ? B MET 147 
117 1 Y 1 B GLU 148 ? B GLU 148 
118 1 Y 1 B TYR 149 ? B TYR 149 
119 1 Y 1 B ALA 150 ? B ALA 150 
120 1 Y 1 B VAL 151 ? B VAL 151 
121 1 Y 1 B ASN 152 ? B ASN 152 
122 1 Y 1 B CYS 153 ? B CYS 153 
123 1 Y 1 B HIS 154 ? B HIS 154 
124 1 Y 1 B VAL 155 ? B VAL 155 
125 1 Y 1 B ILE 156 ? B ILE 156 
126 1 Y 1 B THR 157 ? B THR 157 
127 1 Y 1 B TRP 158 ? B TRP 158 
128 1 Y 1 B TYR 409 ? B TYR 409 
129 1 Y 1 B GLY 410 ? B GLY 410 
130 1 Y 1 B HIS 411 ? B HIS 411 
131 1 Y 1 B ARG 412 ? B ARG 412 
132 1 Y 1 B GLU 413 ? B GLU 413 
133 1 Y 1 B LYS 414 ? B LYS 414 
134 1 Y 1 B THR 415 ? B THR 415 
135 1 Y 1 B TYR 416 ? B TYR 416 
136 1 Y 1 B SER 417 ? B SER 417 
137 1 Y 1 B GLU 418 ? B GLU 418 
138 1 Y 1 B CYS 419 ? B CYS 419 
139 1 Y 1 B GLU 420 ? B GLU 420 
140 1 Y 1 B ASP 421 ? B ASP 421 
141 1 Y 1 B GLY 422 ? B GLY 422 
142 1 Y 1 B THR 423 ? B THR 423 
143 1 Y 1 B TYR 424 ? B TYR 424 
144 1 Y 1 B SER 425 ? B SER 425 
145 1 Y 1 B PRO 426 ? B PRO 426 
146 1 Y 1 B GLU 427 ? B GLU 427 
147 1 Y 1 B ILE 428 ? B ILE 428 
148 1 Y 1 B SER 429 ? B SER 429 
149 1 Y 1 B TRP 430 ? B TRP 430 
150 1 Y 1 B HIS 431 ? B HIS 431 
151 1 Y 1 B HIS 432 ? B HIS 432 
152 1 Y 1 B ARG 433 ? B ARG 433 
153 1 Y 1 B LYS 434 ? B LYS 434 
154 1 Y 1 B GLY 435 ? B GLY 435 
155 1 Y 1 B THR 436 ? B THR 436 
156 1 Y 1 B LYS 437 ? B LYS 437 
157 1 Y 1 B GLY 438 ? B GLY 438 
158 1 Y 1 B SER 439 ? B SER 439 
159 1 Y 1 B GLU 440 ? B GLU 440 
160 1 Y 1 B ASP 441 ? B ASP 441 
161 1 Y 1 B SER 442 ? B SER 442 
162 1 Y 1 B PRO 443 ? B PRO 443 
163 1 Y 1 B PRO 444 ? B PRO 444 
164 1 Y 1 B LYS 445 ? B LYS 445 
165 1 Y 1 B HIS 446 ? B HIS 446 
166 1 Y 1 B ALA 447 ? B ALA 447 
167 1 Y 1 B GLY 448 ? B GLY 448 
168 1 Y 1 B ASN 449 ? B ASN 449 
169 1 Y 1 B ASN 450 ? B ASN 450 
170 1 Y 1 B GLU 451 ? B GLU 451 
171 1 Y 1 B SER 452 ? B SER 452 
172 1 Y 1 B HIS 453 ? B HIS 453 
173 1 Y 1 B SER 454 ? B SER 454 
174 1 Y 1 B SER 455 ? B SER 455 
175 1 Y 1 B ARG 456 ? B ARG 456 
176 1 Y 1 B ARG 457 ? B ARG 457 
177 1 Y 1 B ARG 458 ? B ARG 458 
178 1 Y 1 B ASN 459 ? B ASN 459 
179 1 Y 1 B ARG 460 ? B ARG 460 
180 1 Y 1 B HIS 461 ? B HIS 461 
181 1 Y 1 B SER 462 ? B SER 462 
182 1 Y 1 B LYS 463 ? B LYS 463 
183 1 Y 1 B SER 464 ? B SER 464 
184 1 Y 1 B LYS 465 ? B LYS 465 
185 1 Y 1 B VAL 466 ? B VAL 466 
186 1 Y 1 B THR 467 ? B THR 467 
187 1 Y 1 B ASN 468 ? B ASN 468 
188 1 Y 1 B GLY 469 ? B GLY 469 
189 1 Y 1 B VAL 470 ? B VAL 470 
190 1 Y 1 B GLY 471 ? B GLY 471 
191 1 Y 1 B LYS 472 ? B LYS 472 
192 1 Y 1 B LYS 473 ? B LYS 473 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
C14 C01  C N N 74  
C14 C02  C N N 75  
C14 C03  C N N 76  
C14 C04  C N N 77  
C14 C05  C N N 78  
C14 C06  C N N 79  
C14 C07  C N N 80  
C14 C08  C N N 81  
C14 C09  C N N 82  
C14 C10  C N N 83  
C14 C11  C N N 84  
C14 C12  C N N 85  
C14 C13  C N N 86  
C14 C14  C N N 87  
C14 H011 H N N 88  
C14 H012 H N N 89  
C14 H013 H N N 90  
C14 H021 H N N 91  
C14 H022 H N N 92  
C14 H031 H N N 93  
C14 H032 H N N 94  
C14 H041 H N N 95  
C14 H042 H N N 96  
C14 H051 H N N 97  
C14 H052 H N N 98  
C14 H061 H N N 99  
C14 H062 H N N 100 
C14 H071 H N N 101 
C14 H072 H N N 102 
C14 H081 H N N 103 
C14 H082 H N N 104 
C14 H091 H N N 105 
C14 H092 H N N 106 
C14 H101 H N N 107 
C14 H102 H N N 108 
C14 H111 H N N 109 
C14 H112 H N N 110 
C14 H121 H N N 111 
C14 H122 H N N 112 
C14 H131 H N N 113 
C14 H132 H N N 114 
C14 H141 H N N 115 
C14 H142 H N N 116 
C14 H143 H N N 117 
CYS N    N N N 118 
CYS CA   C N R 119 
CYS C    C N N 120 
CYS O    O N N 121 
CYS CB   C N N 122 
CYS SG   S N N 123 
CYS OXT  O N N 124 
CYS H    H N N 125 
CYS H2   H N N 126 
CYS HA   H N N 127 
CYS HB2  H N N 128 
CYS HB3  H N N 129 
CYS HG   H N N 130 
CYS HXT  H N N 131 
D12 C1   C N N 132 
D12 C2   C N N 133 
D12 C3   C N N 134 
D12 C4   C N N 135 
D12 C5   C N N 136 
D12 C6   C N N 137 
D12 C7   C N N 138 
D12 C8   C N N 139 
D12 C9   C N N 140 
D12 C10  C N N 141 
D12 C11  C N N 142 
D12 C12  C N N 143 
D12 H11  H N N 144 
D12 H12  H N N 145 
D12 H13  H N N 146 
D12 H21  H N N 147 
D12 H22  H N N 148 
D12 H31  H N N 149 
D12 H32  H N N 150 
D12 H41  H N N 151 
D12 H42  H N N 152 
D12 H51  H N N 153 
D12 H52  H N N 154 
D12 H61  H N N 155 
D12 H62  H N N 156 
D12 H71  H N N 157 
D12 H72  H N N 158 
D12 H81  H N N 159 
D12 H82  H N N 160 
D12 H91  H N N 161 
D12 H92  H N N 162 
D12 H101 H N N 163 
D12 H102 H N N 164 
D12 H111 H N N 165 
D12 H112 H N N 166 
D12 H121 H N N 167 
D12 H122 H N N 168 
D12 H123 H N N 169 
GLN N    N N N 170 
GLN CA   C N S 171 
GLN C    C N N 172 
GLN O    O N N 173 
GLN CB   C N N 174 
GLN CG   C N N 175 
GLN CD   C N N 176 
GLN OE1  O N N 177 
GLN NE2  N N N 178 
GLN OXT  O N N 179 
GLN H    H N N 180 
GLN H2   H N N 181 
GLN HA   H N N 182 
GLN HB2  H N N 183 
GLN HB3  H N N 184 
GLN HG2  H N N 185 
GLN HG3  H N N 186 
GLN HE21 H N N 187 
GLN HE22 H N N 188 
GLN HXT  H N N 189 
GLU N    N N N 190 
GLU CA   C N S 191 
GLU C    C N N 192 
GLU O    O N N 193 
GLU CB   C N N 194 
GLU CG   C N N 195 
GLU CD   C N N 196 
GLU OE1  O N N 197 
GLU OE2  O N N 198 
GLU OXT  O N N 199 
GLU H    H N N 200 
GLU H2   H N N 201 
GLU HA   H N N 202 
GLU HB2  H N N 203 
GLU HB3  H N N 204 
GLU HG2  H N N 205 
GLU HG3  H N N 206 
GLU HE2  H N N 207 
GLU HXT  H N N 208 
GLY N    N N N 209 
GLY CA   C N N 210 
GLY C    C N N 211 
GLY O    O N N 212 
GLY OXT  O N N 213 
GLY H    H N N 214 
GLY H2   H N N 215 
GLY HA2  H N N 216 
GLY HA3  H N N 217 
GLY HXT  H N N 218 
HIS N    N N N 219 
HIS CA   C N S 220 
HIS C    C N N 221 
HIS O    O N N 222 
HIS CB   C N N 223 
HIS CG   C Y N 224 
HIS ND1  N Y N 225 
HIS CD2  C Y N 226 
HIS CE1  C Y N 227 
HIS NE2  N Y N 228 
HIS OXT  O N N 229 
HIS H    H N N 230 
HIS H2   H N N 231 
HIS HA   H N N 232 
HIS HB2  H N N 233 
HIS HB3  H N N 234 
HIS HD1  H N N 235 
HIS HD2  H N N 236 
HIS HE1  H N N 237 
HIS HE2  H N N 238 
HIS HXT  H N N 239 
ILE N    N N N 240 
ILE CA   C N S 241 
ILE C    C N N 242 
ILE O    O N N 243 
ILE CB   C N S 244 
ILE CG1  C N N 245 
ILE CG2  C N N 246 
ILE CD1  C N N 247 
ILE OXT  O N N 248 
ILE H    H N N 249 
ILE H2   H N N 250 
ILE HA   H N N 251 
ILE HB   H N N 252 
ILE HG12 H N N 253 
ILE HG13 H N N 254 
ILE HG21 H N N 255 
ILE HG22 H N N 256 
ILE HG23 H N N 257 
ILE HD11 H N N 258 
ILE HD12 H N N 259 
ILE HD13 H N N 260 
ILE HXT  H N N 261 
LBN C1   C N N 262 
LBN N1   N N N 263 
LBN P1   P N N 264 
LBN C2   C N R 265 
LBN C3   C N N 266 
LBN C4   C N N 267 
LBN C5   C N N 268 
LBN C6   C N N 269 
LBN O1   O N N 270 
LBN C7   C N N 271 
LBN C8   C N N 272 
LBN C9   C N N 273 
LBN O2   O N N 274 
LBN C10  C N N 275 
LBN C11  C N N 276 
LBN C12  C N N 277 
LBN O3   O N N 278 
LBN C13  C N N 279 
LBN C14  C N N 280 
LBN C15  C N N 281 
LBN O4   O N N 282 
LBN C16  C N N 283 
LBN C17  C N N 284 
LBN C18  C N N 285 
LBN C19  C N N 286 
LBN C20  C N N 287 
LBN C21  C N N 288 
LBN C22  C N N 289 
LBN C23  C N N 290 
LBN C24  C N N 291 
LBN C25  C N N 292 
LBN O5   O N N 293 
LBN C26  C N N 294 
LBN O6   O N N 295 
LBN C27  C N N 296 
LBN C28  C N N 297 
LBN C29  C N N 298 
LBN C30  C N N 299 
LBN C31  C N N 300 
LBN C32  C N N 301 
LBN C33  C N N 302 
LBN C34  C N N 303 
LBN O7   O N N 304 
LBN C35  C N N 305 
LBN O8   O N N 306 
LBN C36  C N N 307 
LBN C37  C N N 308 
LBN C38  C N N 309 
LBN C39  C N N 310 
LBN C40  C N N 311 
LBN C41  C N N 312 
LBN C42  C N N 313 
LBN H1   H N N 314 
LBN H2   H N N 315 
LBN H3   H N N 316 
LBN H4   H N N 317 
LBN H5   H N N 318 
LBN H6   H N N 319 
LBN H7   H N N 320 
LBN H8   H N N 321 
LBN H9   H N N 322 
LBN H10  H N N 323 
LBN H11  H N N 324 
LBN H12  H N N 325 
LBN H13  H N N 326 
LBN H14  H N N 327 
LBN H15  H N N 328 
LBN H16  H N N 329 
LBN H17  H N N 330 
LBN H18  H N N 331 
LBN H19  H N N 332 
LBN H20  H N N 333 
LBN H21  H N N 334 
LBN H22  H N N 335 
LBN H23  H N N 336 
LBN H24  H N N 337 
LBN H25  H N N 338 
LBN H26  H N N 339 
LBN H27  H N N 340 
LBN H28  H N N 341 
LBN H30  H N N 342 
LBN H31  H N N 343 
LBN H32  H N N 344 
LBN H33  H N N 345 
LBN H34  H N N 346 
LBN H35  H N N 347 
LBN H36  H N N 348 
LBN H37  H N N 349 
LBN H38  H N N 350 
LBN H39  H N N 351 
LBN H40  H N N 352 
LBN H41  H N N 353 
LBN H42  H N N 354 
LBN H43  H N N 355 
LBN H44  H N N 356 
LBN H45  H N N 357 
LBN H46  H N N 358 
LBN H47  H N N 359 
LBN H48  H N N 360 
LBN H49  H N N 361 
LBN H50  H N N 362 
LBN H51  H N N 363 
LBN H52  H N N 364 
LBN H53  H N N 365 
LBN H54  H N N 366 
LBN H55  H N N 367 
LBN H56  H N N 368 
LBN H57  H N N 369 
LBN H58  H N N 370 
LBN H59  H N N 371 
LBN H60  H N N 372 
LBN H61  H N N 373 
LBN H62  H N N 374 
LBN H63  H N N 375 
LBN H64  H N N 376 
LBN H65  H N N 377 
LBN H66  H N N 378 
LBN H67  H N N 379 
LBN H68  H N N 380 
LBN H69  H N N 381 
LBN H70  H N N 382 
LBN H71  H N N 383 
LBN H72  H N N 384 
LBN H73  H N N 385 
LBN H74  H N N 386 
LBN H75  H N N 387 
LBN H76  H N N 388 
LBN H77  H N N 389 
LBN H78  H N N 390 
LBN H79  H N N 391 
LBN H80  H N N 392 
LBN H81  H N N 393 
LBN H82  H N N 394 
LBN H83  H N N 395 
LEU N    N N N 396 
LEU CA   C N S 397 
LEU C    C N N 398 
LEU O    O N N 399 
LEU CB   C N N 400 
LEU CG   C N N 401 
LEU CD1  C N N 402 
LEU CD2  C N N 403 
LEU OXT  O N N 404 
LEU H    H N N 405 
LEU H2   H N N 406 
LEU HA   H N N 407 
LEU HB2  H N N 408 
LEU HB3  H N N 409 
LEU HG   H N N 410 
LEU HD11 H N N 411 
LEU HD12 H N N 412 
LEU HD13 H N N 413 
LEU HD21 H N N 414 
LEU HD22 H N N 415 
LEU HD23 H N N 416 
LEU HXT  H N N 417 
LYS N    N N N 418 
LYS CA   C N S 419 
LYS C    C N N 420 
LYS O    O N N 421 
LYS CB   C N N 422 
LYS CG   C N N 423 
LYS CD   C N N 424 
LYS CE   C N N 425 
LYS NZ   N N N 426 
LYS OXT  O N N 427 
LYS H    H N N 428 
LYS H2   H N N 429 
LYS HA   H N N 430 
LYS HB2  H N N 431 
LYS HB3  H N N 432 
LYS HG2  H N N 433 
LYS HG3  H N N 434 
LYS HD2  H N N 435 
LYS HD3  H N N 436 
LYS HE2  H N N 437 
LYS HE3  H N N 438 
LYS HZ1  H N N 439 
LYS HZ2  H N N 440 
LYS HZ3  H N N 441 
LYS HXT  H N N 442 
MET N    N N N 443 
MET CA   C N S 444 
MET C    C N N 445 
MET O    O N N 446 
MET CB   C N N 447 
MET CG   C N N 448 
MET SD   S N N 449 
MET CE   C N N 450 
MET OXT  O N N 451 
MET H    H N N 452 
MET H2   H N N 453 
MET HA   H N N 454 
MET HB2  H N N 455 
MET HB3  H N N 456 
MET HG2  H N N 457 
MET HG3  H N N 458 
MET HE1  H N N 459 
MET HE2  H N N 460 
MET HE3  H N N 461 
MET HXT  H N N 462 
PHE N    N N N 463 
PHE CA   C N S 464 
PHE C    C N N 465 
PHE O    O N N 466 
PHE CB   C N N 467 
PHE CG   C Y N 468 
PHE CD1  C Y N 469 
PHE CD2  C Y N 470 
PHE CE1  C Y N 471 
PHE CE2  C Y N 472 
PHE CZ   C Y N 473 
PHE OXT  O N N 474 
PHE H    H N N 475 
PHE H2   H N N 476 
PHE HA   H N N 477 
PHE HB2  H N N 478 
PHE HB3  H N N 479 
PHE HD1  H N N 480 
PHE HD2  H N N 481 
PHE HE1  H N N 482 
PHE HE2  H N N 483 
PHE HZ   H N N 484 
PHE HXT  H N N 485 
PRO N    N N N 486 
PRO CA   C N S 487 
PRO C    C N N 488 
PRO O    O N N 489 
PRO CB   C N N 490 
PRO CG   C N N 491 
PRO CD   C N N 492 
PRO OXT  O N N 493 
PRO H    H N N 494 
PRO HA   H N N 495 
PRO HB2  H N N 496 
PRO HB3  H N N 497 
PRO HG2  H N N 498 
PRO HG3  H N N 499 
PRO HD2  H N N 500 
PRO HD3  H N N 501 
PRO HXT  H N N 502 
PSF O2   O N N 503 
PSF O1   O N N 504 
PSF P    P N R 505 
PSF O4   O N N 506 
PSF O3   O N N 507 
PSF C2   C N N 508 
PSF C3   C N N 509 
PSF O11  O N N 510 
PSF O12  O N N 511 
PSF C1   C N N 512 
PSF C4   C N N 513 
PSF C5   C N N 514 
PSF O51  O N N 515 
PSF O52  O N N 516 
PSF C6   C N N 517 
PSF C7   C N N 518 
PSF C13  C N N 519 
PSF C14  C N N 520 
PSF C15  C N N 521 
PSF N    N N N 522 
PSF CA   C N S 523 
PSF CB   C N N 524 
PSF C    C N N 525 
PSF OT1  O N N 526 
PSF OT2  O N N 527 
PSF C8   C N N 528 
PSF C9   C N N 529 
PSF C10  C N N 530 
PSF C16  C N N 531 
PSF C17  C N N 532 
PSF HO3  H N N 533 
PSF H21  H N N 534 
PSF H22  H N N 535 
PSF H31  H N N 536 
PSF H41  H N N 537 
PSF H42  H N N 538 
PSF H61  H N N 539 
PSF H62  H N N 540 
PSF H71  H N N 541 
PSF H72  H N N 542 
PSF H131 H N N 543 
PSF H132 H N N 544 
PSF H141 H N N 545 
PSF H142 H N N 546 
PSF H151 H N N 547 
PSF H152 H N N 548 
PSF H1   H N N 549 
PSF H2   H N N 550 
PSF HA   H N N 551 
PSF HB1  H N N 552 
PSF HB2  H N N 553 
PSF HXT  H N N 554 
PSF H81  H N N 555 
PSF H82  H N N 556 
PSF H91  H N N 557 
PSF H92  H N N 558 
PSF H101 H N N 559 
PSF H102 H N N 560 
PSF H103 H N N 561 
PSF H161 H N N 562 
PSF H162 H N N 563 
PSF H171 H N N 564 
PSF H172 H N N 565 
PSF H173 H N N 566 
SER N    N N N 567 
SER CA   C N S 568 
SER C    C N N 569 
SER O    O N N 570 
SER CB   C N N 571 
SER OG   O N N 572 
SER OXT  O N N 573 
SER H    H N N 574 
SER H2   H N N 575 
SER HA   H N N 576 
SER HB2  H N N 577 
SER HB3  H N N 578 
SER HG   H N N 579 
SER HXT  H N N 580 
T7X C1   C N N 581 
T7X O1   O N N 582 
T7X P1   P N N 583 
T7X C2   C N R 584 
T7X O2   O N N 585 
T7X C3   C N S 586 
T7X O3   O N N 587 
T7X C4   C N N 588 
T7X O4   O N N 589 
T7X C5   C N R 590 
T7X O5   O N N 591 
T7X C6   C N R 592 
T7X O6   O N N 593 
T7X C7   C N N 594 
T7X C8   C N R 595 
T7X C9   C N N 596 
T7X C10  C N N 597 
T7X C11  C N N 598 
T7X O11  O N N 599 
T7X C12  C N N 600 
T7X O12  O N N 601 
T7X C13  C N N 602 
T7X O13  O N N 603 
T7X C14  C N N 604 
T7X C15  C N N 605 
T7X C16  C N N 606 
T7X O16  O N N 607 
T7X C17  C N N 608 
T7X O17  O N N 609 
T7X C18  C N N 610 
T7X O18  O N N 611 
T7X C19  C N N 612 
T7X O19  O N N 613 
T7X C20  C N N 614 
T7X C21  C N N 615 
T7X C22  C N N 616 
T7X C23  C N N 617 
T7X C24  C N N 618 
T7X C25  C N N 619 
T7X C26  C N N 620 
T7X C27  C N N 621 
T7X C31  C N N 622 
T7X C32  C N N 623 
T7X C33  C N N 624 
T7X C34  C N N 625 
T7X C35  C N N 626 
T7X C36  C N N 627 
T7X C37  C N N 628 
T7X C38  C N N 629 
T7X C39  C N N 630 
T7X C40  C N N 631 
T7X C41  C N N 632 
T7X H1   H N N 633 
T7X H2   H N N 634 
T7X H3   H N N 635 
T7X H4   H N N 636 
T7X H5   H N N 637 
T7X H6   H N N 638 
T7X H7   H N N 639 
T7X H8   H N N 640 
T7X H9   H N N 641 
T7X H10  H N N 642 
T7X H11  H N N 643 
T7X H12  H N N 644 
T7X H13  H N N 645 
T7X H14  H N N 646 
T7X H15  H N N 647 
T7X H16  H N N 648 
T7X H17  H N N 649 
T7X H18  H N N 650 
T7X H19  H N N 651 
T7X H20  H N N 652 
T7X H21  H N N 653 
T7X H22  H N N 654 
T7X H23  H N N 655 
T7X H24  H N N 656 
T7X H25  H N N 657 
T7X H26  H N N 658 
T7X H27  H N N 659 
T7X H28  H N N 660 
T7X H29  H N N 661 
T7X H30  H N N 662 
T7X H32  H N N 663 
T7X H34  H N N 664 
T7X H36  H N N 665 
T7X H38  H N N 666 
T7X H40  H N N 667 
T7X H42  H N N 668 
T7X H43  H N N 669 
T7X H44  H N N 670 
T7X H45  H N N 671 
T7X H47  H N N 672 
T7X H48  H N N 673 
T7X H49  H N N 674 
T7X H50  H N N 675 
T7X H51  H N N 676 
T7X H52  H N N 677 
T7X H53  H N N 678 
T7X H54  H N N 679 
T7X H55  H N N 680 
T7X H56  H N N 681 
T7X H57  H N N 682 
T7X H58  H N N 683 
T7X H59  H N N 684 
T7X H60  H N N 685 
T7X H61  H N N 686 
T7X H62  H N N 687 
T7X H63  H N N 688 
T7X H64  H N N 689 
T7X H65  H N N 690 
T7X H66  H N N 691 
T7X H67  H N N 692 
T7X H68  H N N 693 
T7X C28  C N N 694 
T7X C29  C N N 695 
T7X C30  C N N 696 
T7X C42  C N N 697 
T7X C43  C N N 698 
T7X C44  C N N 699 
T7X C45  C N N 700 
T7X C46  C N N 701 
T7X H31  H N N 702 
T7X H33  H N N 703 
T7X H35  H N N 704 
T7X H37  H N N 705 
T7X H39  H N N 706 
T7X H41  H N N 707 
T7X H46  H N N 708 
T7X H69  H N N 709 
T7X H70  H N N 710 
T7X H71  H N N 711 
T7X H72  H N N 712 
T7X H73  H N N 713 
T7X H74  H N N 714 
T7X H75  H N N 715 
T7X H76  H N N 716 
T7X H77  H N N 717 
T7X H78  H N N 718 
T7X H79  H N N 719 
T7X H80  H N N 720 
T7X C47  C N N 721 
T7X H81  H N N 722 
T7X H82  H N N 723 
T7X H83  H N N 724 
THR N    N N N 725 
THR CA   C N S 726 
THR C    C N N 727 
THR O    O N N 728 
THR CB   C N R 729 
THR OG1  O N N 730 
THR CG2  C N N 731 
THR OXT  O N N 732 
THR H    H N N 733 
THR H2   H N N 734 
THR HA   H N N 735 
THR HB   H N N 736 
THR HG1  H N N 737 
THR HG21 H N N 738 
THR HG22 H N N 739 
THR HG23 H N N 740 
THR HXT  H N N 741 
TRP N    N N N 742 
TRP CA   C N S 743 
TRP C    C N N 744 
TRP O    O N N 745 
TRP CB   C N N 746 
TRP CG   C Y N 747 
TRP CD1  C Y N 748 
TRP CD2  C Y N 749 
TRP NE1  N Y N 750 
TRP CE2  C Y N 751 
TRP CE3  C Y N 752 
TRP CZ2  C Y N 753 
TRP CZ3  C Y N 754 
TRP CH2  C Y N 755 
TRP OXT  O N N 756 
TRP H    H N N 757 
TRP H2   H N N 758 
TRP HA   H N N 759 
TRP HB2  H N N 760 
TRP HB3  H N N 761 
TRP HD1  H N N 762 
TRP HE1  H N N 763 
TRP HE3  H N N 764 
TRP HZ2  H N N 765 
TRP HZ3  H N N 766 
TRP HH2  H N N 767 
TRP HXT  H N N 768 
TYR N    N N N 769 
TYR CA   C N S 770 
TYR C    C N N 771 
TYR O    O N N 772 
TYR CB   C N N 773 
TYR CG   C Y N 774 
TYR CD1  C Y N 775 
TYR CD2  C Y N 776 
TYR CE1  C Y N 777 
TYR CE2  C Y N 778 
TYR CZ   C Y N 779 
TYR OH   O N N 780 
TYR OXT  O N N 781 
TYR H    H N N 782 
TYR H2   H N N 783 
TYR HA   H N N 784 
TYR HB2  H N N 785 
TYR HB3  H N N 786 
TYR HD1  H N N 787 
TYR HD2  H N N 788 
TYR HE1  H N N 789 
TYR HE2  H N N 790 
TYR HH   H N N 791 
TYR HXT  H N N 792 
VAL N    N N N 793 
VAL CA   C N S 794 
VAL C    C N N 795 
VAL O    O N N 796 
VAL CB   C N N 797 
VAL CG1  C N N 798 
VAL CG2  C N N 799 
VAL OXT  O N N 800 
VAL H    H N N 801 
VAL H2   H N N 802 
VAL HA   H N N 803 
VAL HB   H N N 804 
VAL HG11 H N N 805 
VAL HG12 H N N 806 
VAL HG13 H N N 807 
VAL HG21 H N N 808 
VAL HG22 H N N 809 
VAL HG23 H N N 810 
VAL HXT  H N N 811 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
C14 C01 C02  sing N N 70  
C14 C01 H011 sing N N 71  
C14 C01 H012 sing N N 72  
C14 C01 H013 sing N N 73  
C14 C02 C03  sing N N 74  
C14 C02 H021 sing N N 75  
C14 C02 H022 sing N N 76  
C14 C03 C04  sing N N 77  
C14 C03 H031 sing N N 78  
C14 C03 H032 sing N N 79  
C14 C04 C05  sing N N 80  
C14 C04 H041 sing N N 81  
C14 C04 H042 sing N N 82  
C14 C05 C06  sing N N 83  
C14 C05 H051 sing N N 84  
C14 C05 H052 sing N N 85  
C14 C06 C07  sing N N 86  
C14 C06 H061 sing N N 87  
C14 C06 H062 sing N N 88  
C14 C07 C08  sing N N 89  
C14 C07 H071 sing N N 90  
C14 C07 H072 sing N N 91  
C14 C08 C09  sing N N 92  
C14 C08 H081 sing N N 93  
C14 C08 H082 sing N N 94  
C14 C09 C10  sing N N 95  
C14 C09 H091 sing N N 96  
C14 C09 H092 sing N N 97  
C14 C10 C11  sing N N 98  
C14 C10 H101 sing N N 99  
C14 C10 H102 sing N N 100 
C14 C11 C12  sing N N 101 
C14 C11 H111 sing N N 102 
C14 C11 H112 sing N N 103 
C14 C12 C13  sing N N 104 
C14 C12 H121 sing N N 105 
C14 C12 H122 sing N N 106 
C14 C13 C14  sing N N 107 
C14 C13 H131 sing N N 108 
C14 C13 H132 sing N N 109 
C14 C14 H141 sing N N 110 
C14 C14 H142 sing N N 111 
C14 C14 H143 sing N N 112 
CYS N   CA   sing N N 113 
CYS N   H    sing N N 114 
CYS N   H2   sing N N 115 
CYS CA  C    sing N N 116 
CYS CA  CB   sing N N 117 
CYS CA  HA   sing N N 118 
CYS C   O    doub N N 119 
CYS C   OXT  sing N N 120 
CYS CB  SG   sing N N 121 
CYS CB  HB2  sing N N 122 
CYS CB  HB3  sing N N 123 
CYS SG  HG   sing N N 124 
CYS OXT HXT  sing N N 125 
D12 C1  C2   sing N N 126 
D12 C1  H11  sing N N 127 
D12 C1  H12  sing N N 128 
D12 C1  H13  sing N N 129 
D12 C2  C3   sing N N 130 
D12 C2  H21  sing N N 131 
D12 C2  H22  sing N N 132 
D12 C3  C4   sing N N 133 
D12 C3  H31  sing N N 134 
D12 C3  H32  sing N N 135 
D12 C4  C5   sing N N 136 
D12 C4  H41  sing N N 137 
D12 C4  H42  sing N N 138 
D12 C5  C6   sing N N 139 
D12 C5  H51  sing N N 140 
D12 C5  H52  sing N N 141 
D12 C6  C7   sing N N 142 
D12 C6  H61  sing N N 143 
D12 C6  H62  sing N N 144 
D12 C7  C8   sing N N 145 
D12 C7  H71  sing N N 146 
D12 C7  H72  sing N N 147 
D12 C8  C9   sing N N 148 
D12 C8  H81  sing N N 149 
D12 C8  H82  sing N N 150 
D12 C9  C10  sing N N 151 
D12 C9  H91  sing N N 152 
D12 C9  H92  sing N N 153 
D12 C10 C11  sing N N 154 
D12 C10 H101 sing N N 155 
D12 C10 H102 sing N N 156 
D12 C11 C12  sing N N 157 
D12 C11 H111 sing N N 158 
D12 C11 H112 sing N N 159 
D12 C12 H121 sing N N 160 
D12 C12 H122 sing N N 161 
D12 C12 H123 sing N N 162 
GLN N   CA   sing N N 163 
GLN N   H    sing N N 164 
GLN N   H2   sing N N 165 
GLN CA  C    sing N N 166 
GLN CA  CB   sing N N 167 
GLN CA  HA   sing N N 168 
GLN C   O    doub N N 169 
GLN C   OXT  sing N N 170 
GLN CB  CG   sing N N 171 
GLN CB  HB2  sing N N 172 
GLN CB  HB3  sing N N 173 
GLN CG  CD   sing N N 174 
GLN CG  HG2  sing N N 175 
GLN CG  HG3  sing N N 176 
GLN CD  OE1  doub N N 177 
GLN CD  NE2  sing N N 178 
GLN NE2 HE21 sing N N 179 
GLN NE2 HE22 sing N N 180 
GLN OXT HXT  sing N N 181 
GLU N   CA   sing N N 182 
GLU N   H    sing N N 183 
GLU N   H2   sing N N 184 
GLU CA  C    sing N N 185 
GLU CA  CB   sing N N 186 
GLU CA  HA   sing N N 187 
GLU C   O    doub N N 188 
GLU C   OXT  sing N N 189 
GLU CB  CG   sing N N 190 
GLU CB  HB2  sing N N 191 
GLU CB  HB3  sing N N 192 
GLU CG  CD   sing N N 193 
GLU CG  HG2  sing N N 194 
GLU CG  HG3  sing N N 195 
GLU CD  OE1  doub N N 196 
GLU CD  OE2  sing N N 197 
GLU OE2 HE2  sing N N 198 
GLU OXT HXT  sing N N 199 
GLY N   CA   sing N N 200 
GLY N   H    sing N N 201 
GLY N   H2   sing N N 202 
GLY CA  C    sing N N 203 
GLY CA  HA2  sing N N 204 
GLY CA  HA3  sing N N 205 
GLY C   O    doub N N 206 
GLY C   OXT  sing N N 207 
GLY OXT HXT  sing N N 208 
HIS N   CA   sing N N 209 
HIS N   H    sing N N 210 
HIS N   H2   sing N N 211 
HIS CA  C    sing N N 212 
HIS CA  CB   sing N N 213 
HIS CA  HA   sing N N 214 
HIS C   O    doub N N 215 
HIS C   OXT  sing N N 216 
HIS CB  CG   sing N N 217 
HIS CB  HB2  sing N N 218 
HIS CB  HB3  sing N N 219 
HIS CG  ND1  sing Y N 220 
HIS CG  CD2  doub Y N 221 
HIS ND1 CE1  doub Y N 222 
HIS ND1 HD1  sing N N 223 
HIS CD2 NE2  sing Y N 224 
HIS CD2 HD2  sing N N 225 
HIS CE1 NE2  sing Y N 226 
HIS CE1 HE1  sing N N 227 
HIS NE2 HE2  sing N N 228 
HIS OXT HXT  sing N N 229 
ILE N   CA   sing N N 230 
ILE N   H    sing N N 231 
ILE N   H2   sing N N 232 
ILE CA  C    sing N N 233 
ILE CA  CB   sing N N 234 
ILE CA  HA   sing N N 235 
ILE C   O    doub N N 236 
ILE C   OXT  sing N N 237 
ILE CB  CG1  sing N N 238 
ILE CB  CG2  sing N N 239 
ILE CB  HB   sing N N 240 
ILE CG1 CD1  sing N N 241 
ILE CG1 HG12 sing N N 242 
ILE CG1 HG13 sing N N 243 
ILE CG2 HG21 sing N N 244 
ILE CG2 HG22 sing N N 245 
ILE CG2 HG23 sing N N 246 
ILE CD1 HD11 sing N N 247 
ILE CD1 HD12 sing N N 248 
ILE CD1 HD13 sing N N 249 
ILE OXT HXT  sing N N 250 
LBN C12 N1   sing N N 251 
LBN O3  P1   sing N N 252 
LBN O2  C9   sing N N 253 
LBN O2  P1   sing N N 254 
LBN C9  C6   sing N N 255 
LBN O4  P1   doub N N 256 
LBN P1  O1   sing N N 257 
LBN C6  N1   sing N N 258 
LBN N1  C15  sing N N 259 
LBN N1  C18  sing N N 260 
LBN O1  C1   sing N N 261 
LBN C2  C1   sing N N 262 
LBN C2  C3   sing N N 263 
LBN C2  O7   sing N N 264 
LBN C3  O5   sing N N 265 
LBN O6  C25  doub N N 266 
LBN O5  C25  sing N N 267 
LBN O7  C34  sing N N 268 
LBN C25 C26  sing N N 269 
LBN C34 C35  sing N N 270 
LBN C34 O8   doub N N 271 
LBN C26 C27  sing N N 272 
LBN C35 C36  sing N N 273 
LBN C27 C28  sing N N 274 
LBN C36 C37  sing N N 275 
LBN C28 C29  sing N N 276 
LBN C37 C38  sing N N 277 
LBN C29 C30  sing N N 278 
LBN C39 C38  sing N N 279 
LBN C39 C40  sing N N 280 
LBN C41 C40  sing N N 281 
LBN C41 C42  sing N N 282 
LBN C30 C31  sing N N 283 
LBN C42 C5   doub N Z 284 
LBN C31 C32  sing N N 285 
LBN C5  C8   sing N N 286 
LBN C8  C11  sing N N 287 
LBN C32 C33  sing N N 288 
LBN C11 C14  sing N N 289 
LBN C33 C4   sing N N 290 
LBN C14 C17  sing N N 291 
LBN C4  C7   sing N N 292 
LBN C17 C20  sing N N 293 
LBN C7  C10  sing N N 294 
LBN C20 C22  sing N N 295 
LBN C10 C13  sing N N 296 
LBN C22 C23  sing N N 297 
LBN C13 C16  sing N N 298 
LBN C23 C24  sing N N 299 
LBN C16 C19  sing N N 300 
LBN C19 C21  sing N N 301 
LBN C1  H1   sing N N 302 
LBN C1  H2   sing N N 303 
LBN C2  H3   sing N N 304 
LBN C3  H4   sing N N 305 
LBN C3  H5   sing N N 306 
LBN C4  H6   sing N N 307 
LBN C4  H7   sing N N 308 
LBN C5  H8   sing N N 309 
LBN C6  H9   sing N N 310 
LBN C6  H10  sing N N 311 
LBN C7  H11  sing N N 312 
LBN C7  H12  sing N N 313 
LBN C8  H13  sing N N 314 
LBN C8  H14  sing N N 315 
LBN C9  H15  sing N N 316 
LBN C9  H16  sing N N 317 
LBN C10 H17  sing N N 318 
LBN C10 H18  sing N N 319 
LBN C11 H19  sing N N 320 
LBN C12 H20  sing N N 321 
LBN C12 H21  sing N N 322 
LBN C12 H22  sing N N 323 
LBN C13 H23  sing N N 324 
LBN C13 H24  sing N N 325 
LBN C14 H25  sing N N 326 
LBN C15 H26  sing N N 327 
LBN C15 H27  sing N N 328 
LBN C15 H28  sing N N 329 
LBN C16 H30  sing N N 330 
LBN C16 H31  sing N N 331 
LBN C17 H32  sing N N 332 
LBN C17 H33  sing N N 333 
LBN C18 H34  sing N N 334 
LBN C18 H35  sing N N 335 
LBN C18 H36  sing N N 336 
LBN C19 H37  sing N N 337 
LBN C19 H38  sing N N 338 
LBN C20 H39  sing N N 339 
LBN C20 H40  sing N N 340 
LBN C21 H41  sing N N 341 
LBN C21 H42  sing N N 342 
LBN C21 H43  sing N N 343 
LBN C22 H44  sing N N 344 
LBN C22 H45  sing N N 345 
LBN C23 H46  sing N N 346 
LBN C23 H47  sing N N 347 
LBN C24 H48  sing N N 348 
LBN C24 H49  sing N N 349 
LBN C24 H50  sing N N 350 
LBN C26 H51  sing N N 351 
LBN C26 H52  sing N N 352 
LBN C27 H53  sing N N 353 
LBN C27 H54  sing N N 354 
LBN C28 H55  sing N N 355 
LBN C28 H56  sing N N 356 
LBN C29 H57  sing N N 357 
LBN C29 H58  sing N N 358 
LBN C30 H59  sing N N 359 
LBN C30 H60  sing N N 360 
LBN C31 H61  sing N N 361 
LBN C31 H62  sing N N 362 
LBN C32 H63  sing N N 363 
LBN C32 H64  sing N N 364 
LBN C33 H65  sing N N 365 
LBN C33 H66  sing N N 366 
LBN C35 H67  sing N N 367 
LBN C35 H68  sing N N 368 
LBN C36 H69  sing N N 369 
LBN C36 H70  sing N N 370 
LBN C37 H71  sing N N 371 
LBN C37 H72  sing N N 372 
LBN C38 H73  sing N N 373 
LBN C38 H74  sing N N 374 
LBN C39 H75  sing N N 375 
LBN C40 H76  sing N N 376 
LBN C41 H77  sing N N 377 
LBN C41 H78  sing N N 378 
LBN C42 H79  sing N N 379 
LBN C11 H80  sing N N 380 
LBN C14 H81  sing N N 381 
LBN C39 H82  sing N N 382 
LBN C40 H83  sing N N 383 
LEU N   CA   sing N N 384 
LEU N   H    sing N N 385 
LEU N   H2   sing N N 386 
LEU CA  C    sing N N 387 
LEU CA  CB   sing N N 388 
LEU CA  HA   sing N N 389 
LEU C   O    doub N N 390 
LEU C   OXT  sing N N 391 
LEU CB  CG   sing N N 392 
LEU CB  HB2  sing N N 393 
LEU CB  HB3  sing N N 394 
LEU CG  CD1  sing N N 395 
LEU CG  CD2  sing N N 396 
LEU CG  HG   sing N N 397 
LEU CD1 HD11 sing N N 398 
LEU CD1 HD12 sing N N 399 
LEU CD1 HD13 sing N N 400 
LEU CD2 HD21 sing N N 401 
LEU CD2 HD22 sing N N 402 
LEU CD2 HD23 sing N N 403 
LEU OXT HXT  sing N N 404 
LYS N   CA   sing N N 405 
LYS N   H    sing N N 406 
LYS N   H2   sing N N 407 
LYS CA  C    sing N N 408 
LYS CA  CB   sing N N 409 
LYS CA  HA   sing N N 410 
LYS C   O    doub N N 411 
LYS C   OXT  sing N N 412 
LYS CB  CG   sing N N 413 
LYS CB  HB2  sing N N 414 
LYS CB  HB3  sing N N 415 
LYS CG  CD   sing N N 416 
LYS CG  HG2  sing N N 417 
LYS CG  HG3  sing N N 418 
LYS CD  CE   sing N N 419 
LYS CD  HD2  sing N N 420 
LYS CD  HD3  sing N N 421 
LYS CE  NZ   sing N N 422 
LYS CE  HE2  sing N N 423 
LYS CE  HE3  sing N N 424 
LYS NZ  HZ1  sing N N 425 
LYS NZ  HZ2  sing N N 426 
LYS NZ  HZ3  sing N N 427 
LYS OXT HXT  sing N N 428 
MET N   CA   sing N N 429 
MET N   H    sing N N 430 
MET N   H2   sing N N 431 
MET CA  C    sing N N 432 
MET CA  CB   sing N N 433 
MET CA  HA   sing N N 434 
MET C   O    doub N N 435 
MET C   OXT  sing N N 436 
MET CB  CG   sing N N 437 
MET CB  HB2  sing N N 438 
MET CB  HB3  sing N N 439 
MET CG  SD   sing N N 440 
MET CG  HG2  sing N N 441 
MET CG  HG3  sing N N 442 
MET SD  CE   sing N N 443 
MET CE  HE1  sing N N 444 
MET CE  HE2  sing N N 445 
MET CE  HE3  sing N N 446 
MET OXT HXT  sing N N 447 
PHE N   CA   sing N N 448 
PHE N   H    sing N N 449 
PHE N   H2   sing N N 450 
PHE CA  C    sing N N 451 
PHE CA  CB   sing N N 452 
PHE CA  HA   sing N N 453 
PHE C   O    doub N N 454 
PHE C   OXT  sing N N 455 
PHE CB  CG   sing N N 456 
PHE CB  HB2  sing N N 457 
PHE CB  HB3  sing N N 458 
PHE CG  CD1  doub Y N 459 
PHE CG  CD2  sing Y N 460 
PHE CD1 CE1  sing Y N 461 
PHE CD1 HD1  sing N N 462 
PHE CD2 CE2  doub Y N 463 
PHE CD2 HD2  sing N N 464 
PHE CE1 CZ   doub Y N 465 
PHE CE1 HE1  sing N N 466 
PHE CE2 CZ   sing Y N 467 
PHE CE2 HE2  sing N N 468 
PHE CZ  HZ   sing N N 469 
PHE OXT HXT  sing N N 470 
PRO N   CA   sing N N 471 
PRO N   CD   sing N N 472 
PRO N   H    sing N N 473 
PRO CA  C    sing N N 474 
PRO CA  CB   sing N N 475 
PRO CA  HA   sing N N 476 
PRO C   O    doub N N 477 
PRO C   OXT  sing N N 478 
PRO CB  CG   sing N N 479 
PRO CB  HB2  sing N N 480 
PRO CB  HB3  sing N N 481 
PRO CG  CD   sing N N 482 
PRO CG  HG2  sing N N 483 
PRO CG  HG3  sing N N 484 
PRO CD  HD2  sing N N 485 
PRO CD  HD3  sing N N 486 
PRO OXT HXT  sing N N 487 
PSF O2  P    sing N N 488 
PSF O2  C2   sing N N 489 
PSF O1  P    sing N N 490 
PSF O1  CB   sing N N 491 
PSF P   O4   doub N N 492 
PSF P   O3   sing N N 493 
PSF O3  HO3  sing N N 494 
PSF C2  C3   sing N N 495 
PSF C2  H21  sing N N 496 
PSF C2  H22  sing N N 497 
PSF C3  O11  sing N N 498 
PSF C3  C4   sing N N 499 
PSF C3  H31  sing N N 500 
PSF O11 C1   sing N N 501 
PSF O12 C1   doub N N 502 
PSF C1  C13  sing N N 503 
PSF C4  O52  sing N N 504 
PSF C4  H41  sing N N 505 
PSF C4  H42  sing N N 506 
PSF C5  O51  doub N N 507 
PSF C5  O52  sing N N 508 
PSF C5  C6   sing N N 509 
PSF C6  C7   sing N N 510 
PSF C6  H61  sing N N 511 
PSF C6  H62  sing N N 512 
PSF C7  C8   sing N N 513 
PSF C7  H71  sing N N 514 
PSF C7  H72  sing N N 515 
PSF C13 C14  sing N N 516 
PSF C13 H131 sing N N 517 
PSF C13 H132 sing N N 518 
PSF C14 C15  sing N N 519 
PSF C14 H141 sing N N 520 
PSF C14 H142 sing N N 521 
PSF C15 C16  sing N N 522 
PSF C15 H151 sing N N 523 
PSF C15 H152 sing N N 524 
PSF N   CA   sing N N 525 
PSF N   H1   sing N N 526 
PSF N   H2   sing N N 527 
PSF CA  CB   sing N N 528 
PSF CA  C    sing N N 529 
PSF CA  HA   sing N N 530 
PSF CB  HB1  sing N N 531 
PSF CB  HB2  sing N N 532 
PSF C   OT1  doub N N 533 
PSF C   OT2  sing N N 534 
PSF OT2 HXT  sing N N 535 
PSF C8  C9   sing N N 536 
PSF C8  H81  sing N N 537 
PSF C8  H82  sing N N 538 
PSF C9  C10  sing N N 539 
PSF C9  H91  sing N N 540 
PSF C9  H92  sing N N 541 
PSF C10 H101 sing N N 542 
PSF C10 H102 sing N N 543 
PSF C10 H103 sing N N 544 
PSF C16 C17  sing N N 545 
PSF C16 H161 sing N N 546 
PSF C16 H162 sing N N 547 
PSF C17 H171 sing N N 548 
PSF C17 H172 sing N N 549 
PSF C17 H173 sing N N 550 
SER N   CA   sing N N 551 
SER N   H    sing N N 552 
SER N   H2   sing N N 553 
SER CA  C    sing N N 554 
SER CA  CB   sing N N 555 
SER CA  HA   sing N N 556 
SER C   O    doub N N 557 
SER C   OXT  sing N N 558 
SER CB  OG   sing N N 559 
SER CB  HB2  sing N N 560 
SER CB  HB3  sing N N 561 
SER OG  HG   sing N N 562 
SER OXT HXT  sing N N 563 
T7X O2  C2   sing N N 564 
T7X O3  C3   sing N N 565 
T7X C2  C3   sing N N 566 
T7X C2  C1   sing N N 567 
T7X O1  C1   sing N N 568 
T7X O1  P1   sing N N 569 
T7X O11 P1   doub N N 570 
T7X O6  C6   sing N N 571 
T7X C3  C4   sing N N 572 
T7X C1  C6   sing N N 573 
T7X C7  C8   sing N N 574 
T7X C7  O13  sing N N 575 
T7X P1  O13  sing N N 576 
T7X P1  O12  sing N N 577 
T7X O17 C10  doub N N 578 
T7X C6  C5   sing N N 579 
T7X C4  O4   sing N N 580 
T7X C4  C5   sing N N 581 
T7X C8  O16  sing N N 582 
T7X C8  C9   sing N N 583 
T7X O16 C10  sing N N 584 
T7X C10 C12  sing N N 585 
T7X C5  O5   sing N N 586 
T7X C9  O18  sing N N 587 
T7X C14 C13  sing N N 588 
T7X C14 C15  sing N N 589 
T7X C13 C12  sing N N 590 
T7X O18 C11  sing N N 591 
T7X C17 C16  sing N N 592 
T7X C17 C18  sing N N 593 
T7X C15 C16  doub N Z 594 
T7X C11 O19  doub N N 595 
T7X C11 C31  sing N N 596 
T7X C20 C21  sing N N 597 
T7X C20 C19  sing N N 598 
T7X C22 C21  doub N E 599 
T7X C22 C23  sing N N 600 
T7X C31 C32  sing N N 601 
T7X C23 C24  sing N N 602 
T7X C24 C25  doub N E 603 
T7X C18 C19  doub N Z 604 
T7X C25 C26  sing N N 605 
T7X C32 C33  sing N N 606 
T7X C33 C34  sing N N 607 
T7X C26 C27  sing N N 608 
T7X C35 C34  sing N N 609 
T7X C35 C36  sing N N 610 
T7X C37 C36  sing N N 611 
T7X C37 C38  sing N N 612 
T7X C41 C40  sing N N 613 
T7X C39 C38  sing N N 614 
T7X C39 C40  sing N N 615 
T7X C1  H1   sing N N 616 
T7X C2  H2   sing N N 617 
T7X O2  H3   sing N N 618 
T7X C3  H4   sing N N 619 
T7X O3  H5   sing N N 620 
T7X C4  H6   sing N N 621 
T7X O4  H7   sing N N 622 
T7X C5  H8   sing N N 623 
T7X O5  H9   sing N N 624 
T7X C6  H10  sing N N 625 
T7X O6  H11  sing N N 626 
T7X C7  H12  sing N N 627 
T7X C7  H13  sing N N 628 
T7X C8  H14  sing N N 629 
T7X C9  H15  sing N N 630 
T7X C9  H16  sing N N 631 
T7X C12 H17  sing N N 632 
T7X C12 H18  sing N N 633 
T7X O12 H19  sing N N 634 
T7X C13 H20  sing N N 635 
T7X C13 H21  sing N N 636 
T7X C14 H22  sing N N 637 
T7X C14 H23  sing N N 638 
T7X C15 H24  sing N N 639 
T7X C16 H25  sing N N 640 
T7X C17 H26  sing N N 641 
T7X C17 H27  sing N N 642 
T7X C18 H28  sing N N 643 
T7X C19 H29  sing N N 644 
T7X C20 H30  sing N N 645 
T7X C21 H32  sing N N 646 
T7X C22 H34  sing N N 647 
T7X C23 H36  sing N N 648 
T7X C24 H38  sing N N 649 
T7X C25 H40  sing N N 650 
T7X C26 H42  sing N N 651 
T7X C26 H43  sing N N 652 
T7X C27 H44  sing N N 653 
T7X C27 H45  sing N N 654 
T7X C31 H47  sing N N 655 
T7X C31 H48  sing N N 656 
T7X C32 H49  sing N N 657 
T7X C32 H50  sing N N 658 
T7X C33 H51  sing N N 659 
T7X C33 H52  sing N N 660 
T7X C34 H53  sing N N 661 
T7X C34 H54  sing N N 662 
T7X C35 H55  sing N N 663 
T7X C35 H56  sing N N 664 
T7X C36 H57  sing N N 665 
T7X C36 H58  sing N N 666 
T7X C37 H59  sing N N 667 
T7X C37 H60  sing N N 668 
T7X C38 H61  sing N N 669 
T7X C38 H62  sing N N 670 
T7X C39 H63  sing N N 671 
T7X C39 H64  sing N N 672 
T7X C40 H65  sing N N 673 
T7X C40 H66  sing N N 674 
T7X C41 H67  sing N N 675 
T7X C41 H68  sing N N 676 
T7X C27 C28  sing N N 677 
T7X C28 C29  sing N N 678 
T7X C29 C30  sing N N 679 
T7X C41 C42  sing N N 680 
T7X C42 C43  sing N N 681 
T7X C43 C44  sing N N 682 
T7X C44 C45  sing N N 683 
T7X C45 C46  sing N N 684 
T7X C20 H31  sing N N 685 
T7X C23 H33  sing N N 686 
T7X C28 H35  sing N N 687 
T7X C28 H37  sing N N 688 
T7X C29 H39  sing N N 689 
T7X C29 H41  sing N N 690 
T7X C30 H46  sing N N 691 
T7X C30 H69  sing N N 692 
T7X C30 H70  sing N N 693 
T7X C42 H71  sing N N 694 
T7X C42 H72  sing N N 695 
T7X C43 H73  sing N N 696 
T7X C43 H74  sing N N 697 
T7X C44 H75  sing N N 698 
T7X C44 H76  sing N N 699 
T7X C45 H77  sing N N 700 
T7X C45 H78  sing N N 701 
T7X C46 H79  sing N N 702 
T7X C46 H80  sing N N 703 
T7X C46 C47  sing N N 704 
T7X C47 H81  sing N N 705 
T7X C47 H82  sing N N 706 
T7X C47 H83  sing N N 707 
THR N   CA   sing N N 708 
THR N   H    sing N N 709 
THR N   H2   sing N N 710 
THR CA  C    sing N N 711 
THR CA  CB   sing N N 712 
THR CA  HA   sing N N 713 
THR C   O    doub N N 714 
THR C   OXT  sing N N 715 
THR CB  OG1  sing N N 716 
THR CB  CG2  sing N N 717 
THR CB  HB   sing N N 718 
THR OG1 HG1  sing N N 719 
THR CG2 HG21 sing N N 720 
THR CG2 HG22 sing N N 721 
THR CG2 HG23 sing N N 722 
THR OXT HXT  sing N N 723 
TRP N   CA   sing N N 724 
TRP N   H    sing N N 725 
TRP N   H2   sing N N 726 
TRP CA  C    sing N N 727 
TRP CA  CB   sing N N 728 
TRP CA  HA   sing N N 729 
TRP C   O    doub N N 730 
TRP C   OXT  sing N N 731 
TRP CB  CG   sing N N 732 
TRP CB  HB2  sing N N 733 
TRP CB  HB3  sing N N 734 
TRP CG  CD1  doub Y N 735 
TRP CG  CD2  sing Y N 736 
TRP CD1 NE1  sing Y N 737 
TRP CD1 HD1  sing N N 738 
TRP CD2 CE2  doub Y N 739 
TRP CD2 CE3  sing Y N 740 
TRP NE1 CE2  sing Y N 741 
TRP NE1 HE1  sing N N 742 
TRP CE2 CZ2  sing Y N 743 
TRP CE3 CZ3  doub Y N 744 
TRP CE3 HE3  sing N N 745 
TRP CZ2 CH2  doub Y N 746 
TRP CZ2 HZ2  sing N N 747 
TRP CZ3 CH2  sing Y N 748 
TRP CZ3 HZ3  sing N N 749 
TRP CH2 HH2  sing N N 750 
TRP OXT HXT  sing N N 751 
TYR N   CA   sing N N 752 
TYR N   H    sing N N 753 
TYR N   H2   sing N N 754 
TYR CA  C    sing N N 755 
TYR CA  CB   sing N N 756 
TYR CA  HA   sing N N 757 
TYR C   O    doub N N 758 
TYR C   OXT  sing N N 759 
TYR CB  CG   sing N N 760 
TYR CB  HB2  sing N N 761 
TYR CB  HB3  sing N N 762 
TYR CG  CD1  doub Y N 763 
TYR CG  CD2  sing Y N 764 
TYR CD1 CE1  sing Y N 765 
TYR CD1 HD1  sing N N 766 
TYR CD2 CE2  doub Y N 767 
TYR CD2 HD2  sing N N 768 
TYR CE1 CZ   doub Y N 769 
TYR CE1 HE1  sing N N 770 
TYR CE2 CZ   sing Y N 771 
TYR CE2 HE2  sing N N 772 
TYR CZ  OH   sing N N 773 
TYR OH  HH   sing N N 774 
TYR OXT HXT  sing N N 775 
VAL N   CA   sing N N 776 
VAL N   H    sing N N 777 
VAL N   H2   sing N N 778 
VAL CA  C    sing N N 779 
VAL CA  CB   sing N N 780 
VAL CA  HA   sing N N 781 
VAL C   O    doub N N 782 
VAL C   OXT  sing N N 783 
VAL CB  CG1  sing N N 784 
VAL CB  CG2  sing N N 785 
VAL CB  HB   sing N N 786 
VAL CG1 HG11 sing N N 787 
VAL CG1 HG12 sing N N 788 
VAL CG1 HG13 sing N N 789 
VAL CG2 HG21 sing N N 790 
VAL CG2 HG22 sing N N 791 
VAL CG2 HG23 sing N N 792 
VAL OXT HXT  sing N N 793 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-11-25 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           9KQF 
_em_admin.last_update        2025-04-02 
_em_admin.map_release_date   2025-04-02 
_em_admin.title              'Cryo-EM structure of PSS1 in the absence of calcium or L-serine' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     NONE 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         48 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ?      ?           
'MODEL REFINEMENT'         ? 2  ? ? ? PHENIX 1.20.1_4487 
'IMAGE ACQUISITION'        ? 3  ? ? 1 ?      ?           
MASKING                    ? 4  ? ? ? ?      ?           
'CTF CORRECTION'           ? 5  1 ? ? ?      ?           
'LAYERLINE INDEXING'       ? 6  ? ? ? ?      ?           
'DIFFRACTION INDEXING'     ? 7  ? ? ? ?      ?           
'MODEL FITTING'            ? 8  ? ? ? ?      ?           
OTHER                      ? 9  ? ? ? ?      ?           
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ?      ?           
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ?      ?           
CLASSIFICATION             ? 12 1 ? ? ?      ?           
RECONSTRUCTION             ? 13 1 ? ? ?      ?           
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Other government' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           'LG-QS-202203-05; 22PJ1410300;32471016' 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9KQF 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . ASP A 1 14  ? 138.734 130.613 115.267 1.00 116.63 ? 14  ASP A N   1 
ATOM   2    C CA  . ASP A 1 14  ? 137.644 131.547 115.517 1.00 116.65 ? 14  ASP A CA  1 
ATOM   3    C C   . ASP A 1 14  ? 136.300 130.846 115.369 1.00 115.26 ? 14  ASP A C   1 
ATOM   4    O O   . ASP A 1 14  ? 135.702 130.417 116.353 1.00 110.58 ? 14  ASP A O   1 
ATOM   5    C CB  . ASP A 1 14  ? 137.732 132.736 114.563 1.00 118.60 ? 14  ASP A CB  1 
ATOM   6    C CG  . ASP A 1 14  ? 139.161 133.140 114.273 1.00 117.13 ? 14  ASP A CG  1 
ATOM   7    O OD1 . ASP A 1 14  ? 139.934 133.324 115.235 1.00 117.08 ? 14  ASP A OD1 1 
ATOM   8    O OD2 . ASP A 1 14  ? 139.512 133.268 113.082 1.00 114.42 ? 14  ASP A OD2 1 
ATOM   9    N N   . VAL A 1 15  ? 135.827 130.742 114.126 1.00 120.51 ? 15  VAL A N   1 
ATOM   10   C CA  . VAL A 1 15  ? 134.605 129.989 113.860 1.00 119.57 ? 15  VAL A CA  1 
ATOM   11   C C   . VAL A 1 15  ? 134.813 128.517 114.183 1.00 118.14 ? 15  VAL A C   1 
ATOM   12   O O   . VAL A 1 15  ? 133.958 127.873 114.802 1.00 117.81 ? 15  VAL A O   1 
ATOM   13   C CB  . VAL A 1 15  ? 134.156 130.197 112.402 1.00 119.20 ? 15  VAL A CB  1 
ATOM   14   C CG1 . VAL A 1 15  ? 133.140 129.139 112.001 1.00 117.83 ? 15  VAL A CG1 1 
ATOM   15   C CG2 . VAL A 1 15  ? 133.576 131.592 112.222 1.00 116.68 ? 15  VAL A CG2 1 
ATOM   16   N N   . ASN A 1 16  ? 135.955 127.961 113.770 1.00 113.81 ? 16  ASN A N   1 
ATOM   17   C CA  . ASN A 1 16  ? 136.277 126.585 114.132 1.00 112.20 ? 16  ASN A CA  1 
ATOM   18   C C   . ASN A 1 16  ? 136.627 126.470 115.609 1.00 114.01 ? 16  ASN A C   1 
ATOM   19   O O   . ASN A 1 16  ? 136.312 125.459 116.247 1.00 112.68 ? 16  ASN A O   1 
ATOM   20   C CB  . ASN A 1 16  ? 137.426 126.065 113.271 1.00 111.01 ? 16  ASN A CB  1 
ATOM   21   C CG  . ASN A 1 16  ? 137.040 125.909 111.817 1.00 116.48 ? 16  ASN A CG  1 
ATOM   22   O OD1 . ASN A 1 16  ? 135.906 126.190 111.431 1.00 116.51 ? 16  ASN A OD1 1 
ATOM   23   N ND2 . ASN A 1 16  ? 137.985 125.461 110.999 1.00 117.25 ? 16  ASN A ND2 1 
ATOM   24   N N   . TYR A 1 17  ? 137.281 127.492 116.169 1.00 108.99 ? 17  TYR A N   1 
ATOM   25   C CA  . TYR A 1 17  ? 137.701 127.426 117.565 1.00 104.72 ? 17  TYR A CA  1 
ATOM   26   C C   . TYR A 1 17  ? 136.507 127.232 118.489 1.00 103.70 ? 17  TYR A C   1 
ATOM   27   O O   . TYR A 1 17  ? 136.507 126.337 119.341 1.00 106.47 ? 17  TYR A O   1 
ATOM   28   C CB  . TYR A 1 17  ? 138.474 128.689 117.951 1.00 103.28 ? 17  TYR A CB  1 
ATOM   29   C CG  . TYR A 1 17  ? 138.152 129.182 119.344 1.00 105.26 ? 17  TYR A CG  1 
ATOM   30   C CD1 . TYR A 1 17  ? 138.611 128.507 120.469 1.00 105.94 ? 17  TYR A CD1 1 
ATOM   31   C CD2 . TYR A 1 17  ? 137.368 130.312 119.534 1.00 105.45 ? 17  TYR A CD2 1 
ATOM   32   C CE1 . TYR A 1 17  ? 138.303 128.948 121.740 1.00 104.54 ? 17  TYR A CE1 1 
ATOM   33   C CE2 . TYR A 1 17  ? 137.057 130.760 120.801 1.00 106.98 ? 17  TYR A CE2 1 
ATOM   34   C CZ  . TYR A 1 17  ? 137.527 130.075 121.900 1.00 105.37 ? 17  TYR A CZ  1 
ATOM   35   O OH  . TYR A 1 17  ? 137.216 130.520 123.161 1.00 105.13 ? 17  TYR A OH  1 
ATOM   36   N N   . LYS A 1 18  ? 135.477 128.066 118.338 1.00 97.85  ? 18  LYS A N   1 
ATOM   37   C CA  . LYS A 1 18  ? 134.306 127.931 119.194 1.00 98.84  ? 18  LYS A CA  1 
ATOM   38   C C   . LYS A 1 18  ? 133.582 126.621 118.933 1.00 96.47  ? 18  LYS A C   1 
ATOM   39   O O   . LYS A 1 18  ? 132.981 126.051 119.850 1.00 96.52  ? 18  LYS A O   1 
ATOM   40   C CB  . LYS A 1 18  ? 133.363 129.116 118.988 1.00 98.90  ? 18  LYS A CB  1 
ATOM   41   C CG  . LYS A 1 18  ? 132.337 129.290 120.095 1.00 101.64 ? 18  LYS A CG  1 
ATOM   42   C CD  . LYS A 1 18  ? 132.959 129.924 121.329 1.00 102.27 ? 18  LYS A CD  1 
ATOM   43   C CE  . LYS A 1 18  ? 133.149 131.421 121.150 1.00 100.98 ? 18  LYS A CE  1 
ATOM   44   N NZ  . LYS A 1 18  ? 131.875 132.165 121.325 1.00 98.24  ? 18  LYS A NZ  1 
ATOM   45   N N   . MET A 1 19  ? 133.624 126.129 117.694 1.00 99.42  ? 19  MET A N   1 
ATOM   46   C CA  . MET A 1 19  ? 133.024 124.834 117.400 1.00 99.82  ? 19  MET A CA  1 
ATOM   47   C C   . MET A 1 19  ? 133.885 123.699 117.934 1.00 97.94  ? 19  MET A C   1 
ATOM   48   O O   . MET A 1 19  ? 133.362 122.706 118.450 1.00 105.35 ? 19  MET A O   1 
ATOM   49   C CB  . MET A 1 19  ? 132.803 124.681 115.896 1.00 102.19 ? 19  MET A CB  1 
ATOM   50   C CG  . MET A 1 19  ? 132.872 123.245 115.404 1.00 102.66 ? 19  MET A CG  1 
ATOM   51   S SD  . MET A 1 19  ? 132.930 123.099 113.610 1.00 113.93 ? 19  MET A SD  1 
ATOM   52   C CE  . MET A 1 19  ? 132.921 121.318 113.426 1.00 99.05  ? 19  MET A CE  1 
ATOM   53   N N   . HIS A 1 20  ? 135.208 123.823 117.816 1.00 84.23  ? 20  HIS A N   1 
ATOM   54   C CA  . HIS A 1 20  ? 136.089 122.780 118.330 1.00 86.66  ? 20  HIS A CA  1 
ATOM   55   C C   . HIS A 1 20  ? 135.995 122.679 119.844 1.00 87.99  ? 20  HIS A C   1 
ATOM   56   O O   . HIS A 1 20  ? 136.008 121.575 120.400 1.00 84.68  ? 20  HIS A O   1 
ATOM   57   C CB  . HIS A 1 20  ? 137.528 123.042 117.898 1.00 90.03  ? 20  HIS A CB  1 
ATOM   58   C CG  . HIS A 1 20  ? 137.966 122.202 116.743 1.00 90.67  ? 20  HIS A CG  1 
ATOM   59   N ND1 . HIS A 1 20  ? 138.496 120.940 116.901 1.00 88.26  ? 20  HIS A ND1 1 
ATOM   60   C CD2 . HIS A 1 20  ? 137.944 122.438 115.411 1.00 91.92  ? 20  HIS A CD2 1 
ATOM   61   C CE1 . HIS A 1 20  ? 138.782 120.435 115.714 1.00 89.39  ? 20  HIS A CE1 1 
ATOM   62   N NE2 . HIS A 1 20  ? 138.459 121.325 114.793 1.00 92.51  ? 20  HIS A NE2 1 
ATOM   63   N N   . PHE A 1 21  ? 135.906 123.818 120.528 1.00 78.59  ? 21  PHE A N   1 
ATOM   64   C CA  . PHE A 1 21  ? 135.730 123.789 121.973 1.00 72.31  ? 21  PHE A CA  1 
ATOM   65   C C   . PHE A 1 21  ? 134.356 123.262 122.359 1.00 73.80  ? 21  PHE A C   1 
ATOM   66   O O   . PHE A 1 21  ? 134.221 122.587 123.384 1.00 82.97  ? 21  PHE A O   1 
ATOM   67   C CB  . PHE A 1 21  ? 135.945 125.178 122.559 1.00 70.51  ? 21  PHE A CB  1 
ATOM   68   C CG  . PHE A 1 21  ? 135.498 125.302 123.977 1.00 72.56  ? 21  PHE A CG  1 
ATOM   69   C CD1 . PHE A 1 21  ? 136.141 124.605 124.980 1.00 72.83  ? 21  PHE A CD1 1 
ATOM   70   C CD2 . PHE A 1 21  ? 134.432 126.112 124.310 1.00 75.38  ? 21  PHE A CD2 1 
ATOM   71   C CE1 . PHE A 1 21  ? 135.733 124.718 126.283 1.00 69.12  ? 21  PHE A CE1 1 
ATOM   72   C CE2 . PHE A 1 21  ? 134.021 126.227 125.614 1.00 75.90  ? 21  PHE A CE2 1 
ATOM   73   C CZ  . PHE A 1 21  ? 134.675 125.531 126.600 1.00 74.08  ? 21  PHE A CZ  1 
ATOM   74   N N   . ARG A 1 22  ? 133.328 123.556 121.563 1.00 74.17  ? 22  ARG A N   1 
ATOM   75   C CA  . ARG A 1 22  ? 132.009 123.002 121.838 1.00 70.41  ? 22  ARG A CA  1 
ATOM   76   C C   . ARG A 1 22  ? 132.001 121.484 121.746 1.00 71.89  ? 22  ARG A C   1 
ATOM   77   O O   . ARG A 1 22  ? 131.166 120.841 122.384 1.00 79.33  ? 22  ARG A O   1 
ATOM   78   C CB  . ARG A 1 22  ? 130.977 123.588 120.880 1.00 73.89  ? 22  ARG A CB  1 
ATOM   79   C CG  . ARG A 1 22  ? 129.542 123.400 121.325 1.00 72.86  ? 22  ARG A CG  1 
ATOM   80   C CD  . ARG A 1 22  ? 128.790 124.715 121.312 1.00 77.18  ? 22  ARG A CD  1 
ATOM   81   N NE  . ARG A 1 22  ? 128.710 125.277 119.970 1.00 87.91  ? 22  ARG A NE  1 
ATOM   82   C CZ  . ARG A 1 22  ? 128.835 126.567 119.690 1.00 86.65  ? 22  ARG A CZ  1 
ATOM   83   N NH1 . ARG A 1 22  ? 129.043 127.464 120.639 1.00 84.61  ? 22  ARG A NH1 1 
ATOM   84   N NH2 . ARG A 1 22  ? 128.750 126.966 118.424 1.00 81.77  ? 22  ARG A NH2 1 
ATOM   85   N N   . MET A 1 23  ? 132.914 120.898 120.973 1.00 76.52  ? 23  MET A N   1 
ATOM   86   C CA  . MET A 1 23  ? 133.035 119.449 120.922 1.00 77.20  ? 23  MET A CA  1 
ATOM   87   C C   . MET A 1 23  ? 133.686 118.878 122.172 1.00 81.96  ? 23  MET A C   1 
ATOM   88   O O   . MET A 1 23  ? 133.576 117.674 122.418 1.00 82.79  ? 23  MET A O   1 
ATOM   89   C CB  . MET A 1 23  ? 133.836 119.035 119.688 1.00 81.77  ? 23  MET A CB  1 
ATOM   90   C CG  . MET A 1 23  ? 133.089 119.215 118.381 1.00 84.41  ? 23  MET A CG  1 
ATOM   91   S SD  . MET A 1 23  ? 134.178 119.203 116.946 1.00 98.31  ? 23  MET A SD  1 
ATOM   92   C CE  . MET A 1 23  ? 135.505 118.153 117.530 1.00 84.42  ? 23  MET A CE  1 
ATOM   93   N N   . ILE A 1 24  ? 134.366 119.708 122.956 1.00 70.16  ? 24  ILE A N   1 
ATOM   94   C CA  . ILE A 1 24  ? 134.912 119.273 124.236 1.00 62.27  ? 24  ILE A CA  1 
ATOM   95   C C   . ILE A 1 24  ? 133.943 119.558 125.374 1.00 67.99  ? 24  ILE A C   1 
ATOM   96   O O   . ILE A 1 24  ? 133.714 118.703 126.229 1.00 74.61  ? 24  ILE A O   1 
ATOM   97   C CB  . ILE A 1 24  ? 136.274 119.946 124.490 1.00 67.42  ? 24  ILE A CB  1 
ATOM   98   C CG1 . ILE A 1 24  ? 137.219 119.738 123.313 1.00 68.77  ? 24  ILE A CG1 1 
ATOM   99   C CG2 . ILE A 1 24  ? 136.902 119.405 125.745 1.00 74.59  ? 24  ILE A CG2 1 
ATOM   100  C CD1 . ILE A 1 24  ? 138.609 120.270 123.577 1.00 68.37  ? 24  ILE A CD1 1 
ATOM   101  N N   . ASN A 1 25  ? 133.360 120.755 125.404 1.00 54.10  ? 25  ASN A N   1 
ATOM   102  C CA  . ASN A 1 25  ? 132.480 121.119 126.507 1.00 52.73  ? 25  ASN A CA  1 
ATOM   103  C C   . ASN A 1 25  ? 131.103 120.485 126.365 1.00 60.89  ? 25  ASN A C   1 
ATOM   104  O O   . ASN A 1 25  ? 130.690 119.683 127.206 1.00 65.80  ? 25  ASN A O   1 
ATOM   105  C CB  . ASN A 1 25  ? 132.353 122.638 126.599 1.00 57.78  ? 25  ASN A CB  1 
ATOM   106  C CG  . ASN A 1 25  ? 132.823 123.174 127.921 1.00 64.60  ? 25  ASN A CG  1 
ATOM   107  O OD1 . ASN A 1 25  ? 133.646 122.559 128.592 1.00 69.87  ? 25  ASN A OD1 1 
ATOM   108  N ND2 . ASN A 1 25  ? 132.291 124.323 128.315 1.00 61.69  ? 25  ASN A ND2 1 
ATOM   109  N N   . GLU A 1 26  ? 130.374 120.831 125.308 1.00 66.12  ? 26  GLU A N   1 
ATOM   110  C CA  . GLU A 1 26  ? 128.982 120.417 125.147 1.00 61.86  ? 26  GLU A CA  1 
ATOM   111  C C   . GLU A 1 26  ? 128.868 119.546 123.904 1.00 65.11  ? 26  GLU A C   1 
ATOM   112  O O   . GLU A 1 26  ? 128.542 120.028 122.820 1.00 77.72  ? 26  GLU A O   1 
ATOM   113  C CB  . GLU A 1 26  ? 128.070 121.633 125.062 1.00 65.43  ? 26  GLU A CB  1 
ATOM   114  C CG  . GLU A 1 26  ? 127.909 122.378 126.372 1.00 74.79  ? 26  GLU A CG  1 
ATOM   115  C CD  . GLU A 1 26  ? 127.848 123.881 126.186 1.00 83.45  ? 26  GLU A CD  1 
ATOM   116  O OE1 . GLU A 1 26  ? 128.808 124.454 125.630 1.00 81.54  ? 26  GLU A OE1 1 
ATOM   117  O OE2 . GLU A 1 26  ? 126.841 124.490 126.600 1.00 81.80  ? 26  GLU A OE2 1 
ATOM   118  N N   . GLN A 1 27  ? 129.120 118.254 124.069 1.00 63.27  ? 27  GLN A N   1 
ATOM   119  C CA  . GLN A 1 27  ? 128.958 117.325 122.962 1.00 63.30  ? 27  GLN A CA  1 
ATOM   120  C C   . GLN A 1 27  ? 127.478 117.084 122.702 1.00 67.38  ? 27  GLN A C   1 
ATOM   121  O O   . GLN A 1 27  ? 126.708 116.830 123.632 1.00 73.42  ? 27  GLN A O   1 
ATOM   122  C CB  . GLN A 1 27  ? 129.665 116.009 123.266 1.00 65.58  ? 27  GLN A CB  1 
ATOM   123  C CG  . GLN A 1 27  ? 129.573 114.995 122.149 1.00 68.46  ? 27  GLN A CG  1 
ATOM   124  C CD  . GLN A 1 27  ? 130.640 115.197 121.103 1.00 76.52  ? 27  GLN A CD  1 
ATOM   125  O OE1 . GLN A 1 27  ? 131.512 116.050 121.251 1.00 72.13  ? 27  GLN A OE1 1 
ATOM   126  N NE2 . GLN A 1 27  ? 130.578 114.415 120.035 1.00 80.66  ? 27  GLN A NE2 1 
ATOM   127  N N   . GLN A 1 28  ? 127.081 117.164 121.437 1.00 69.58  ? 28  GLN A N   1 
ATOM   128  C CA  . GLN A 1 28  ? 125.687 117.002 121.057 1.00 72.88  ? 28  GLN A CA  1 
ATOM   129  C C   . GLN A 1 28  ? 125.371 115.540 120.773 1.00 76.37  ? 28  GLN A C   1 
ATOM   130  O O   . GLN A 1 28  ? 126.246 114.752 120.409 1.00 80.59  ? 28  GLN A O   1 
ATOM   131  C CB  . GLN A 1 28  ? 125.361 117.850 119.829 1.00 71.83  ? 28  GLN A CB  1 
ATOM   132  C CG  . GLN A 1 28  ? 124.657 119.155 120.148 1.00 75.07  ? 28  GLN A CG  1 
ATOM   133  C CD  . GLN A 1 28  ? 125.624 120.258 120.522 1.00 79.04  ? 28  GLN A CD  1 
ATOM   134  O OE1 . GLN A 1 28  ? 126.712 120.360 119.959 1.00 76.56  ? 28  GLN A OE1 1 
ATOM   135  N NE2 . GLN A 1 28  ? 125.231 121.092 121.477 1.00 80.10  ? 28  GLN A NE2 1 
ATOM   136  N N   . VAL A 1 29  ? 124.101 115.188 120.941 1.00 76.30  ? 29  VAL A N   1 
ATOM   137  C CA  . VAL A 1 29  ? 123.638 113.829 120.686 1.00 72.53  ? 29  VAL A CA  1 
ATOM   138  C C   . VAL A 1 29  ? 123.365 113.667 119.199 1.00 74.52  ? 29  VAL A C   1 
ATOM   139  O O   . VAL A 1 29  ? 122.660 114.481 118.592 1.00 80.56  ? 29  VAL A O   1 
ATOM   140  C CB  . VAL A 1 29  ? 122.380 113.521 121.509 1.00 74.09  ? 29  VAL A CB  1 
ATOM   141  C CG1 . VAL A 1 29  ? 122.104 112.035 121.501 1.00 71.91  ? 29  VAL A CG1 1 
ATOM   142  C CG2 . VAL A 1 29  ? 122.530 114.043 122.924 1.00 72.49  ? 29  VAL A CG2 1 
ATOM   143  N N   . GLU A 1 30  ? 123.917 112.615 118.609 1.00 80.89  ? 30  GLU A N   1 
ATOM   144  C CA  . GLU A 1 30  ? 123.754 112.345 117.190 1.00 83.33  ? 30  GLU A CA  1 
ATOM   145  C C   . GLU A 1 30  ? 122.681 111.288 116.963 1.00 87.21  ? 30  GLU A C   1 
ATOM   146  O O   . GLU A 1 30  ? 122.525 110.356 117.754 1.00 89.17  ? 30  GLU A O   1 
ATOM   147  C CB  . GLU A 1 30  ? 125.072 111.883 116.568 1.00 84.05  ? 30  GLU A CB  1 
ATOM   148  C CG  . GLU A 1 30  ? 125.992 113.016 116.161 1.00 86.22  ? 30  GLU A CG  1 
ATOM   149  C CD  . GLU A 1 30  ? 127.386 112.535 115.821 1.00 90.37  ? 30  GLU A CD  1 
ATOM   150  O OE1 . GLU A 1 30  ? 127.979 111.808 116.643 1.00 91.49  ? 30  GLU A OE1 1 
ATOM   151  O OE2 . GLU A 1 30  ? 127.888 112.884 114.732 1.00 87.44  ? 30  GLU A OE2 1 
ATOM   152  N N   . ASP A 1 31  ? 121.942 111.448 115.864 1.00 87.32  ? 31  ASP A N   1 
ATOM   153  C CA  . ASP A 1 31  ? 120.937 110.481 115.426 1.00 86.40  ? 31  ASP A CA  1 
ATOM   154  C C   . ASP A 1 31  ? 119.864 110.276 116.497 1.00 86.34  ? 31  ASP A C   1 
ATOM   155  O O   . ASP A 1 31  ? 119.690 109.188 117.047 1.00 82.93  ? 31  ASP A O   1 
ATOM   156  C CB  . ASP A 1 31  ? 121.599 109.153 115.041 1.00 87.96  ? 31  ASP A CB  1 
ATOM   157  C CG  . ASP A 1 31  ? 120.715 108.290 114.164 1.00 90.57  ? 31  ASP A CG  1 
ATOM   158  O OD1 . ASP A 1 31  ? 119.478 108.447 114.214 1.00 89.70  ? 31  ASP A OD1 1 
ATOM   159  O OD2 . ASP A 1 31  ? 121.263 107.451 113.419 1.00 92.03  ? 31  ASP A OD2 1 
ATOM   160  N N   . ILE A 1 32  ? 119.138 111.354 116.783 1.00 87.21  ? 32  ILE A N   1 
ATOM   161  C CA  . ILE A 1 32  ? 118.074 111.325 117.781 1.00 83.75  ? 32  ILE A CA  1 
ATOM   162  C C   . ILE A 1 32  ? 116.832 110.718 117.140 1.00 86.74  ? 32  ILE A C   1 
ATOM   163  O O   . ILE A 1 32  ? 116.214 111.328 116.265 1.00 88.44  ? 32  ILE A O   1 
ATOM   164  C CB  . ILE A 1 32  ? 117.782 112.724 118.330 1.00 80.49  ? 32  ILE A CB  1 
ATOM   165  C CG1 . ILE A 1 32  ? 118.973 113.244 119.132 1.00 80.65  ? 32  ILE A CG1 1 
ATOM   166  C CG2 . ILE A 1 32  ? 116.540 112.699 119.188 1.00 84.53  ? 32  ILE A CG2 1 
ATOM   167  C CD1 . ILE A 1 32  ? 118.988 114.747 119.283 1.00 84.12  ? 32  ILE A CD1 1 
ATOM   168  N N   . THR A 1 33  ? 116.459 109.516 117.578 1.00 94.38  ? 33  THR A N   1 
ATOM   169  C CA  . THR A 1 33  ? 115.263 108.842 117.081 1.00 96.95  ? 33  THR A CA  1 
ATOM   170  C C   . THR A 1 33  ? 114.072 109.057 118.008 1.00 97.04  ? 33  THR A C   1 
ATOM   171  O O   . THR A 1 33  ? 113.017 109.524 117.572 1.00 100.03 ? 33  THR A O   1 
ATOM   172  C CB  . THR A 1 33  ? 115.532 107.345 116.898 1.00 95.76  ? 33  THR A CB  1 
ATOM   173  O OG1 . THR A 1 33  ? 116.050 106.800 118.117 1.00 96.41  ? 33  THR A OG1 1 
ATOM   174  C CG2 . THR A 1 33  ? 116.533 107.123 115.781 1.00 93.05  ? 33  THR A CG2 1 
ATOM   175  N N   . ILE A 1 34  ? 114.222 108.718 119.287 1.00 82.54  ? 34  ILE A N   1 
ATOM   176  C CA  . ILE A 1 34  ? 113.188 109.011 120.270 1.00 80.49  ? 34  ILE A CA  1 
ATOM   177  C C   . ILE A 1 34  ? 113.382 110.441 120.747 1.00 85.99  ? 34  ILE A C   1 
ATOM   178  O O   . ILE A 1 34  ? 114.088 110.690 121.729 1.00 89.22  ? 34  ILE A O   1 
ATOM   179  C CB  . ILE A 1 34  ? 113.225 108.019 121.444 1.00 79.28  ? 34  ILE A CB  1 
ATOM   180  C CG1 . ILE A 1 34  ? 113.185 106.584 120.926 1.00 83.41  ? 34  ILE A CG1 1 
ATOM   181  C CG2 . ILE A 1 34  ? 112.066 108.267 122.385 1.00 85.25  ? 34  ILE A CG2 1 
ATOM   182  C CD1 . ILE A 1 34  ? 112.936 105.556 122.003 1.00 86.98  ? 34  ILE A CD1 1 
ATOM   183  N N   . ASP A 1 35  ? 112.755 111.391 120.051 1.00 87.18  ? 35  ASP A N   1 
ATOM   184  C CA  . ASP A 1 35  ? 112.929 112.803 120.369 1.00 87.72  ? 35  ASP A CA  1 
ATOM   185  C C   . ASP A 1 35  ? 112.371 113.161 121.738 1.00 87.90  ? 35  ASP A C   1 
ATOM   186  O O   . ASP A 1 35  ? 112.711 114.220 122.273 1.00 88.73  ? 35  ASP A O   1 
ATOM   187  C CB  . ASP A 1 35  ? 112.265 113.664 119.294 1.00 91.11  ? 35  ASP A CB  1 
ATOM   188  C CG  . ASP A 1 35  ? 112.607 115.136 119.428 1.00 95.29  ? 35  ASP A CG  1 
ATOM   189  O OD1 . ASP A 1 35  ? 111.796 115.978 118.989 1.00 96.85  ? 35  ASP A OD1 1 
ATOM   190  O OD2 . ASP A 1 35  ? 113.690 115.451 119.963 1.00 92.20  ? 35  ASP A OD2 1 
ATOM   191  N N   . PHE A 1 36  ? 111.529 112.304 122.316 1.00 83.59  ? 36  PHE A N   1 
ATOM   192  C CA  . PHE A 1 36  ? 110.957 112.596 123.625 1.00 84.93  ? 36  PHE A CA  1 
ATOM   193  C C   . PHE A 1 36  ? 112.044 112.716 124.685 1.00 85.87  ? 36  PHE A C   1 
ATOM   194  O O   . PHE A 1 36  ? 111.974 113.585 125.561 1.00 86.64  ? 36  PHE A O   1 
ATOM   195  C CB  . PHE A 1 36  ? 109.944 111.509 123.994 1.00 86.22  ? 36  PHE A CB  1 
ATOM   196  C CG  . PHE A 1 36  ? 109.972 111.102 125.441 1.00 86.88  ? 36  PHE A CG  1 
ATOM   197  C CD1 . PHE A 1 36  ? 109.542 111.968 126.435 1.00 87.64  ? 36  PHE A CD1 1 
ATOM   198  C CD2 . PHE A 1 36  ? 110.427 109.848 125.806 1.00 84.29  ? 36  PHE A CD2 1 
ATOM   199  C CE1 . PHE A 1 36  ? 109.571 111.591 127.760 1.00 84.98  ? 36  PHE A CE1 1 
ATOM   200  C CE2 . PHE A 1 36  ? 110.456 109.466 127.129 1.00 85.91  ? 36  PHE A CE2 1 
ATOM   201  C CZ  . PHE A 1 36  ? 110.028 110.339 128.109 1.00 84.42  ? 36  PHE A CZ  1 
ATOM   202  N N   . PHE A 1 37  ? 113.066 111.864 124.613 1.00 76.60  ? 37  PHE A N   1 
ATOM   203  C CA  . PHE A 1 37  ? 114.105 111.846 125.634 1.00 74.28  ? 37  PHE A CA  1 
ATOM   204  C C   . PHE A 1 37  ? 114.973 113.094 125.631 1.00 77.31  ? 37  PHE A C   1 
ATOM   205  O O   . PHE A 1 37  ? 115.734 113.291 126.581 1.00 79.43  ? 37  PHE A O   1 
ATOM   206  C CB  . PHE A 1 37  ? 114.994 110.620 125.454 1.00 74.09  ? 37  PHE A CB  1 
ATOM   207  C CG  . PHE A 1 37  ? 114.537 109.423 126.227 1.00 74.44  ? 37  PHE A CG  1 
ATOM   208  C CD1 . PHE A 1 37  ? 114.702 109.365 127.596 1.00 75.25  ? 37  PHE A CD1 1 
ATOM   209  C CD2 . PHE A 1 37  ? 113.943 108.355 125.585 1.00 74.15  ? 37  PHE A CD2 1 
ATOM   210  C CE1 . PHE A 1 37  ? 114.281 108.266 128.307 1.00 77.52  ? 37  PHE A CE1 1 
ATOM   211  C CE2 . PHE A 1 37  ? 113.524 107.255 126.294 1.00 73.28  ? 37  PHE A CE2 1 
ATOM   212  C CZ  . PHE A 1 37  ? 113.694 107.211 127.655 1.00 75.40  ? 37  PHE A CZ  1 
ATOM   213  N N   . TYR A 1 38  ? 114.886 113.936 124.601 1.00 77.83  ? 38  TYR A N   1 
ATOM   214  C CA  . TYR A 1 38  ? 115.751 115.099 124.490 1.00 73.40  ? 38  TYR A CA  1 
ATOM   215  C C   . TYR A 1 38  ? 115.012 116.423 124.376 1.00 70.58  ? 38  TYR A C   1 
ATOM   216  O O   . TYR A 1 38  ? 115.659 117.473 124.439 1.00 68.58  ? 38  TYR A O   1 
ATOM   217  C CB  . TYR A 1 38  ? 116.690 114.951 123.284 1.00 71.00  ? 38  TYR A CB  1 
ATOM   218  C CG  . TYR A 1 38  ? 117.590 113.745 123.371 1.00 70.92  ? 38  TYR A CG  1 
ATOM   219  C CD1 . TYR A 1 38  ? 118.671 113.727 124.234 1.00 75.61  ? 38  TYR A CD1 1 
ATOM   220  C CD2 . TYR A 1 38  ? 117.356 112.623 122.595 1.00 69.24  ? 38  TYR A CD2 1 
ATOM   221  C CE1 . TYR A 1 38  ? 119.495 112.630 124.321 1.00 75.73  ? 38  TYR A CE1 1 
ATOM   222  C CE2 . TYR A 1 38  ? 118.176 111.522 122.676 1.00 71.99  ? 38  TYR A CE2 1 
ATOM   223  C CZ  . TYR A 1 38  ? 119.243 111.532 123.542 1.00 71.20  ? 38  TYR A CZ  1 
ATOM   224  O OH  . TYR A 1 38  ? 120.069 110.441 123.632 1.00 71.07  ? 38  TYR A OH  1 
ATOM   225  N N   . ARG A 1 39  ? 113.701 116.415 124.210 1.00 83.10  ? 39  ARG A N   1 
ATOM   226  C CA  . ARG A 1 39  ? 112.951 117.661 124.145 1.00 79.98  ? 39  ARG A CA  1 
ATOM   227  C C   . ARG A 1 39  ? 112.910 118.300 125.525 1.00 81.10  ? 39  ARG A C   1 
ATOM   228  O O   . ARG A 1 39  ? 112.424 117.669 126.472 1.00 85.03  ? 39  ARG A O   1 
ATOM   229  C CB  . ARG A 1 39  ? 111.536 117.406 123.640 1.00 80.12  ? 39  ARG A CB  1 
ATOM   230  C CG  . ARG A 1 39  ? 111.350 117.629 122.151 1.00 79.84  ? 39  ARG A CG  1 
ATOM   231  C CD  . ARG A 1 39  ? 109.895 117.459 121.758 1.00 80.94  ? 39  ARG A CD  1 
ATOM   232  N NE  . ARG A 1 39  ? 108.993 117.999 122.768 1.00 86.89  ? 39  ARG A NE  1 
ATOM   233  C CZ  . ARG A 1 39  ? 107.905 118.708 122.500 1.00 87.61  ? 39  ARG A CZ  1 
ATOM   234  N NH1 . ARG A 1 39  ? 107.542 118.972 121.256 1.00 84.76  ? 39  ARG A NH1 1 
ATOM   235  N NH2 . ARG A 1 39  ? 107.162 119.162 123.505 1.00 83.94  ? 39  ARG A NH2 1 
ATOM   236  N N   . PRO A 1 40  ? 113.399 119.525 125.692 1.00 71.06  ? 40  PRO A N   1 
ATOM   237  C CA  . PRO A 1 40  ? 113.359 120.155 127.012 1.00 64.29  ? 40  PRO A CA  1 
ATOM   238  C C   . PRO A 1 40  ? 111.936 120.456 127.445 1.00 70.66  ? 40  PRO A C   1 
ATOM   239  O O   . PRO A 1 40  ? 111.058 120.747 126.631 1.00 76.52  ? 40  PRO A O   1 
ATOM   240  C CB  . PRO A 1 40  ? 114.156 121.444 126.809 1.00 61.86  ? 40  PRO A CB  1 
ATOM   241  C CG  . PRO A 1 40  ? 113.971 121.752 125.386 1.00 66.37  ? 40  PRO A CG  1 
ATOM   242  C CD  . PRO A 1 40  ? 113.940 120.434 124.672 1.00 69.39  ? 40  PRO A CD  1 
ATOM   243  N N   . HIS A 1 41  ? 111.716 120.377 128.752 1.00 73.13  ? 41  HIS A N   1 
ATOM   244  C CA  . HIS A 1 41  ? 110.432 120.703 129.358 1.00 67.88  ? 41  HIS A CA  1 
ATOM   245  C C   . HIS A 1 41  ? 110.668 121.560 130.595 1.00 70.70  ? 41  HIS A C   1 
ATOM   246  O O   . HIS A 1 41  ? 110.155 121.291 131.680 1.00 69.36  ? 41  HIS A O   1 
ATOM   247  C CB  . HIS A 1 41  ? 109.652 119.435 129.679 1.00 68.52  ? 41  HIS A CB  1 
ATOM   248  C CG  . HIS A 1 41  ? 109.112 118.744 128.468 1.00 74.13  ? 41  HIS A CG  1 
ATOM   249  N ND1 . HIS A 1 41  ? 109.295 117.399 128.234 1.00 78.45  ? 41  HIS A ND1 1 
ATOM   250  C CD2 . HIS A 1 41  ? 108.399 119.215 127.418 1.00 70.46  ? 41  HIS A CD2 1 
ATOM   251  C CE1 . HIS A 1 41  ? 108.713 117.069 127.095 1.00 76.51  ? 41  HIS A CE1 1 
ATOM   252  N NE2 . HIS A 1 41  ? 108.161 118.153 126.580 1.00 74.22  ? 41  HIS A NE2 1 
ATOM   253  N N   . THR A 1 42  ? 111.469 122.612 130.426 1.00 61.12  ? 42  THR A N   1 
ATOM   254  C CA  . THR A 1 42  ? 111.993 123.355 131.566 1.00 53.99  ? 42  THR A CA  1 
ATOM   255  C C   . THR A 1 42  ? 110.895 124.035 132.378 1.00 59.73  ? 42  THR A C   1 
ATOM   256  O O   . THR A 1 42  ? 111.066 124.250 133.582 1.00 63.34  ? 42  THR A O   1 
ATOM   257  C CB  . THR A 1 42  ? 113.019 124.371 131.076 1.00 43.16  ? 42  THR A CB  1 
ATOM   258  O OG1 . THR A 1 42  ? 113.378 125.245 132.147 1.00 59.23  ? 42  THR A OG1 1 
ATOM   259  C CG2 . THR A 1 42  ? 112.456 125.180 129.941 1.00 49.92  ? 42  THR A CG2 1 
ATOM   260  N N   . ILE A 1 43  ? 109.766 124.380 131.757 1.00 66.40  ? 43  ILE A N   1 
ATOM   261  C CA  . ILE A 1 43  ? 108.661 124.946 132.528 1.00 52.96  ? 43  ILE A CA  1 
ATOM   262  C C   . ILE A 1 43  ? 108.047 123.886 133.433 1.00 58.13  ? 43  ILE A C   1 
ATOM   263  O O   . ILE A 1 43  ? 107.646 124.173 134.568 1.00 68.64  ? 43  ILE A O   1 
ATOM   264  C CB  . ILE A 1 43  ? 107.613 125.577 131.596 1.00 58.11  ? 43  ILE A CB  1 
ATOM   265  C CG1 . ILE A 1 43  ? 108.189 126.819 130.922 1.00 65.32  ? 43  ILE A CG1 1 
ATOM   266  C CG2 . ILE A 1 43  ? 106.378 125.962 132.372 1.00 57.22  ? 43  ILE A CG2 1 
ATOM   267  C CD1 . ILE A 1 43  ? 107.191 127.575 130.085 1.00 61.46  ? 43  ILE A CD1 1 
ATOM   268  N N   . THR A 1 44  ? 107.961 122.646 132.951 1.00 62.44  ? 44  THR A N   1 
ATOM   269  C CA  . THR A 1 44  ? 107.518 121.558 133.816 1.00 61.36  ? 44  THR A CA  1 
ATOM   270  C C   . THR A 1 44  ? 108.485 121.360 134.974 1.00 62.98  ? 44  THR A C   1 
ATOM   271  O O   . THR A 1 44  ? 108.067 121.064 136.096 1.00 69.57  ? 44  THR A O   1 
ATOM   272  C CB  . THR A 1 44  ? 107.370 120.268 133.013 1.00 61.14  ? 44  THR A CB  1 
ATOM   273  O OG1 . THR A 1 44  ? 106.555 120.511 131.862 1.00 67.52  ? 44  THR A OG1 1 
ATOM   274  C CG2 . THR A 1 44  ? 106.714 119.198 133.854 1.00 66.23  ? 44  THR A CG2 1 
ATOM   275  N N   . LEU A 1 45  ? 109.784 121.528 134.721 1.00 57.64  ? 45  LEU A N   1 
ATOM   276  C CA  . LEU A 1 45  ? 110.765 121.462 135.799 1.00 56.30  ? 45  LEU A CA  1 
ATOM   277  C C   . LEU A 1 45  ? 110.540 122.574 136.816 1.00 56.51  ? 45  LEU A C   1 
ATOM   278  O O   . LEU A 1 45  ? 110.635 122.347 138.027 1.00 64.88  ? 45  LEU A O   1 
ATOM   279  C CB  . LEU A 1 45  ? 112.174 121.543 135.221 1.00 53.60  ? 45  LEU A CB  1 
ATOM   280  C CG  . LEU A 1 45  ? 113.296 120.933 136.046 1.00 53.70  ? 45  LEU A CG  1 
ATOM   281  C CD1 . LEU A 1 45  ? 113.069 119.453 136.180 1.00 60.51  ? 45  LEU A CD1 1 
ATOM   282  C CD2 . LEU A 1 45  ? 114.621 121.202 135.377 1.00 57.33  ? 45  LEU A CD2 1 
ATOM   283  N N   . LEU A 1 46  ? 110.241 123.783 136.339 1.00 50.73  ? 46  LEU A N   1 
ATOM   284  C CA  . LEU A 1 46  ? 109.943 124.894 137.240 1.00 49.94  ? 46  LEU A CA  1 
ATOM   285  C C   . LEU A 1 46  ? 108.732 124.581 138.110 1.00 52.74  ? 46  LEU A C   1 
ATOM   286  O O   . LEU A 1 46  ? 108.755 124.781 139.333 1.00 63.65  ? 46  LEU A O   1 
ATOM   287  C CB  . LEU A 1 46  ? 109.720 126.163 136.412 1.00 49.84  ? 46  LEU A CB  1 
ATOM   288  C CG  . LEU A 1 46  ? 109.659 127.569 137.001 1.00 43.65  ? 46  LEU A CG  1 
ATOM   289  C CD1 . LEU A 1 46  ? 109.826 128.572 135.891 1.00 50.38  ? 46  LEU A CD1 1 
ATOM   290  C CD2 . LEU A 1 46  ? 108.327 127.796 137.630 1.00 49.02  ? 46  LEU A CD2 1 
ATOM   291  N N   . SER A 1 47  ? 107.664 124.079 137.492 1.00 48.35  ? 47  SER A N   1 
ATOM   292  C CA  . SER A 1 47  ? 106.465 123.742 138.248 1.00 50.17  ? 47  SER A CA  1 
ATOM   293  C C   . SER A 1 47  ? 106.743 122.642 139.260 1.00 57.07  ? 47  SER A C   1 
ATOM   294  O O   . SER A 1 47  ? 106.255 122.695 140.395 1.00 64.90  ? 47  SER A O   1 
ATOM   295  C CB  . SER A 1 47  ? 105.346 123.322 137.302 1.00 53.61  ? 47  SER A CB  1 
ATOM   296  O OG  . SER A 1 47  ? 104.093 123.389 137.954 1.00 65.74  ? 47  SER A OG  1 
ATOM   297  N N   . PHE A 1 48  ? 107.521 121.633 138.867 1.00 57.94  ? 48  PHE A N   1 
ATOM   298  C CA  . PHE A 1 48  ? 107.848 120.545 139.780 1.00 51.01  ? 48  PHE A CA  1 
ATOM   299  C C   . PHE A 1 48  ? 108.627 121.057 140.981 1.00 56.90  ? 48  PHE A C   1 
ATOM   300  O O   . PHE A 1 48  ? 108.331 120.693 142.123 1.00 65.47  ? 48  PHE A O   1 
ATOM   301  C CB  . PHE A 1 48  ? 108.640 119.465 139.045 1.00 54.97  ? 48  PHE A CB  1 
ATOM   302  C CG  . PHE A 1 48  ? 109.576 118.691 139.928 1.00 63.49  ? 48  PHE A CG  1 
ATOM   303  C CD1 . PHE A 1 48  ? 109.100 117.691 140.757 1.00 61.85  ? 48  PHE A CD1 1 
ATOM   304  C CD2 . PHE A 1 48  ? 110.935 118.958 139.924 1.00 59.95  ? 48  PHE A CD2 1 
ATOM   305  C CE1 . PHE A 1 48  ? 109.958 116.978 141.568 1.00 60.39  ? 48  PHE A CE1 1 
ATOM   306  C CE2 . PHE A 1 48  ? 111.797 118.248 140.734 1.00 61.71  ? 48  PHE A CE2 1 
ATOM   307  C CZ  . PHE A 1 48  ? 111.307 117.257 141.556 1.00 64.50  ? 48  PHE A CZ  1 
ATOM   308  N N   . THR A 1 49  ? 109.628 121.912 140.746 1.00 51.86  ? 49  THR A N   1 
ATOM   309  C CA  . THR A 1 49  ? 110.407 122.436 141.864 1.00 49.49  ? 49  THR A CA  1 
ATOM   310  C C   . THR A 1 49  ? 109.541 123.264 142.799 1.00 57.28  ? 49  THR A C   1 
ATOM   311  O O   . THR A 1 49  ? 109.634 123.127 144.024 1.00 66.62  ? 49  THR A O   1 
ATOM   312  C CB  . THR A 1 49  ? 111.583 123.272 141.367 1.00 46.60  ? 49  THR A CB  1 
ATOM   313  O OG1 . THR A 1 49  ? 111.094 124.392 140.626 1.00 59.68  ? 49  THR A OG1 1 
ATOM   314  C CG2 . THR A 1 49  ? 112.493 122.445 140.490 1.00 56.25  ? 49  THR A CG2 1 
ATOM   315  N N   . ILE A 1 50  ? 108.682 124.122 142.246 1.00 48.49  ? 50  ILE A N   1 
ATOM   316  C CA  . ILE A 1 50  ? 107.857 124.968 143.102 1.00 42.87  ? 50  ILE A CA  1 
ATOM   317  C C   . ILE A 1 50  ? 106.885 124.130 143.921 1.00 55.38  ? 50  ILE A C   1 
ATOM   318  O O   . ILE A 1 50  ? 106.714 124.357 145.124 1.00 63.28  ? 50  ILE A O   1 
ATOM   319  C CB  . ILE A 1 50  ? 107.126 126.031 142.270 1.00 43.61  ? 50  ILE A CB  1 
ATOM   320  C CG1 . ILE A 1 50  ? 108.120 127.074 141.788 1.00 52.04  ? 50  ILE A CG1 1 
ATOM   321  C CG2 . ILE A 1 50  ? 106.043 126.693 143.086 1.00 48.48  ? 50  ILE A CG2 1 
ATOM   322  C CD1 . ILE A 1 50  ? 107.492 128.114 140.946 1.00 58.17  ? 50  ILE A CD1 1 
ATOM   323  N N   . VAL A 1 51  ? 106.234 123.150 143.293 1.00 48.50  ? 51  VAL A N   1 
ATOM   324  C CA  . VAL A 1 51  ? 105.275 122.329 144.024 1.00 47.52  ? 51  VAL A CA  1 
ATOM   325  C C   . VAL A 1 51  ? 105.982 121.489 145.082 1.00 57.87  ? 51  VAL A C   1 
ATOM   326  O O   . VAL A 1 51  ? 105.474 121.316 146.199 1.00 63.55  ? 51  VAL A O   1 
ATOM   327  C CB  . VAL A 1 51  ? 104.467 121.461 143.046 1.00 49.04  ? 51  VAL A CB  1 
ATOM   328  C CG1 . VAL A 1 51  ? 103.667 120.422 143.799 1.00 58.33  ? 51  VAL A CG1 1 
ATOM   329  C CG2 . VAL A 1 51  ? 103.551 122.335 142.222 1.00 48.51  ? 51  VAL A CG2 1 
ATOM   330  N N   . SER A 1 52  ? 107.167 120.964 144.761 1.00 52.48  ? 52  SER A N   1 
ATOM   331  C CA  . SER A 1 52  ? 107.922 120.195 145.742 1.00 50.37  ? 52  SER A CA  1 
ATOM   332  C C   . SER A 1 52  ? 108.304 121.052 146.938 1.00 56.88  ? 52  SER A C   1 
ATOM   333  O O   . SER A 1 52  ? 108.214 120.603 148.087 1.00 61.30  ? 52  SER A O   1 
ATOM   334  C CB  . SER A 1 52  ? 109.167 119.602 145.092 1.00 50.85  ? 52  SER A CB  1 
ATOM   335  O OG  . SER A 1 52  ? 108.812 118.697 144.066 1.00 59.77  ? 52  SER A OG  1 
ATOM   336  N N   . LEU A 1 53  ? 108.739 122.289 146.693 1.00 48.50  ? 53  LEU A N   1 
ATOM   337  C CA  . LEU A 1 53  ? 109.093 123.154 147.810 1.00 47.73  ? 53  LEU A CA  1 
ATOM   338  C C   . LEU A 1 53  ? 107.866 123.527 148.626 1.00 53.93  ? 53  LEU A C   1 
ATOM   339  O O   . LEU A 1 53  ? 107.941 123.619 149.854 1.00 65.99  ? 53  LEU A O   1 
ATOM   340  C CB  . LEU A 1 53  ? 109.815 124.408 147.326 1.00 51.79  ? 53  LEU A CB  1 
ATOM   341  C CG  . LEU A 1 53  ? 111.338 124.307 147.358 1.00 54.10  ? 53  LEU A CG  1 
ATOM   342  C CD1 . LEU A 1 53  ? 111.830 124.262 148.785 1.00 56.60  ? 53  LEU A CD1 1 
ATOM   343  C CD2 . LEU A 1 53  ? 111.797 123.095 146.629 1.00 54.83  ? 53  LEU A CD2 1 
ATOM   344  N N   . MET A 1 54  ? 106.725 123.742 147.969 1.00 51.73  ? 54  MET A N   1 
ATOM   345  C CA  . MET A 1 54  ? 105.504 124.019 148.718 1.00 55.71  ? 54  MET A CA  1 
ATOM   346  C C   . MET A 1 54  ? 105.154 122.857 149.633 1.00 55.67  ? 54  MET A C   1 
ATOM   347  O O   . MET A 1 54  ? 104.793 123.059 150.799 1.00 55.65  ? 54  MET A O   1 
ATOM   348  C CB  . MET A 1 54  ? 104.346 124.313 147.769 1.00 53.12  ? 54  MET A CB  1 
ATOM   349  C CG  . MET A 1 54  ? 104.471 125.619 147.025 1.00 54.07  ? 54  MET A CG  1 
ATOM   350  S SD  . MET A 1 54  ? 102.881 126.418 146.789 1.00 79.65  ? 54  MET A SD  1 
ATOM   351  C CE  . MET A 1 54  ? 102.293 125.536 145.355 1.00 61.67  ? 54  MET A CE  1 
ATOM   352  N N   . TYR A 1 55  ? 105.265 121.630 149.125 1.00 56.96  ? 55  TYR A N   1 
ATOM   353  C CA  . TYR A 1 55  ? 104.977 120.471 149.961 1.00 56.57  ? 55  TYR A CA  1 
ATOM   354  C C   . TYR A 1 55  ? 105.945 120.388 151.134 1.00 63.71  ? 55  TYR A C   1 
ATOM   355  O O   . TYR A 1 55  ? 105.527 120.283 152.294 1.00 71.58  ? 55  TYR A O   1 
ATOM   356  C CB  . TYR A 1 55  ? 105.033 119.192 149.135 1.00 55.82  ? 55  TYR A CB  1 
ATOM   357  C CG  . TYR A 1 55  ? 104.747 117.962 149.954 1.00 60.41  ? 55  TYR A CG  1 
ATOM   358  C CD1 . TYR A 1 55  ? 103.472 117.709 150.435 1.00 60.97  ? 55  TYR A CD1 1 
ATOM   359  C CD2 . TYR A 1 55  ? 105.753 117.062 150.263 1.00 62.12  ? 55  TYR A CD2 1 
ATOM   360  C CE1 . TYR A 1 55  ? 103.205 116.589 151.190 1.00 65.56  ? 55  TYR A CE1 1 
ATOM   361  C CE2 . TYR A 1 55  ? 105.496 115.938 151.016 1.00 66.47  ? 55  TYR A CE2 1 
ATOM   362  C CZ  . TYR A 1 55  ? 104.221 115.707 151.478 1.00 70.08  ? 55  TYR A CZ  1 
ATOM   363  O OH  . TYR A 1 55  ? 103.961 114.587 152.231 1.00 68.09  ? 55  TYR A OH  1 
ATOM   364  N N   . PHE A 1 56  ? 107.248 120.454 150.853 1.00 65.64  ? 56  PHE A N   1 
ATOM   365  C CA  . PHE A 1 56  ? 108.247 120.324 151.907 1.00 61.82  ? 56  PHE A CA  1 
ATOM   366  C C   . PHE A 1 56  ? 108.270 121.510 152.857 1.00 63.04  ? 56  PHE A C   1 
ATOM   367  O O   . PHE A 1 56  ? 108.915 121.425 153.905 1.00 72.40  ? 56  PHE A O   1 
ATOM   368  C CB  . PHE A 1 56  ? 109.635 120.135 151.302 1.00 56.38  ? 56  PHE A CB  1 
ATOM   369  C CG  . PHE A 1 56  ? 109.855 118.773 150.727 1.00 62.75  ? 56  PHE A CG  1 
ATOM   370  C CD1 . PHE A 1 56  ? 109.522 117.645 151.449 1.00 65.38  ? 56  PHE A CD1 1 
ATOM   371  C CD2 . PHE A 1 56  ? 110.398 118.620 149.467 1.00 62.83  ? 56  PHE A CD2 1 
ATOM   372  C CE1 . PHE A 1 56  ? 109.720 116.390 150.926 1.00 64.61  ? 56  PHE A CE1 1 
ATOM   373  C CE2 . PHE A 1 56  ? 110.600 117.367 148.939 1.00 62.50  ? 56  PHE A CE2 1 
ATOM   374  C CZ  . PHE A 1 56  ? 110.259 116.250 149.669 1.00 63.90  ? 56  PHE A CZ  1 
ATOM   375  N N   . ALA A 1 57  ? 107.602 122.608 152.522 1.00 51.24  ? 57  ALA A N   1 
ATOM   376  C CA  . ALA A 1 57  ? 107.538 123.752 153.415 1.00 48.25  ? 57  ALA A CA  1 
ATOM   377  C C   . ALA A 1 57  ? 106.258 123.810 154.228 1.00 60.55  ? 57  ALA A C   1 
ATOM   378  O O   . ALA A 1 57  ? 106.278 124.326 155.349 1.00 65.83  ? 57  ALA A O   1 
ATOM   379  C CB  . ALA A 1 57  ? 107.678 125.050 152.621 1.00 50.15  ? 57  ALA A CB  1 
ATOM   380  N N   . PHE A 1 58  ? 105.146 123.297 153.705 1.00 64.10  ? 58  PHE A N   1 
ATOM   381  C CA  . PHE A 1 58  ? 103.882 123.385 154.421 1.00 65.45  ? 58  PHE A CA  1 
ATOM   382  C C   . PHE A 1 58  ? 103.466 122.083 155.090 1.00 64.49  ? 58  PHE A C   1 
ATOM   383  O O   . PHE A 1 58  ? 102.557 122.104 155.925 1.00 69.32  ? 58  PHE A O   1 
ATOM   384  C CB  . PHE A 1 58  ? 102.768 123.848 153.476 1.00 60.38  ? 58  PHE A CB  1 
ATOM   385  C CG  . PHE A 1 58  ? 103.062 125.147 152.791 1.00 58.63  ? 58  PHE A CG  1 
ATOM   386  C CD1 . PHE A 1 58  ? 103.783 126.135 153.433 1.00 54.14  ? 58  PHE A CD1 1 
ATOM   387  C CD2 . PHE A 1 58  ? 102.614 125.384 151.505 1.00 63.66  ? 58  PHE A CD2 1 
ATOM   388  C CE1 . PHE A 1 58  ? 104.056 127.327 152.805 1.00 55.65  ? 58  PHE A CE1 1 
ATOM   389  C CE2 . PHE A 1 58  ? 102.884 126.577 150.875 1.00 61.87  ? 58  PHE A CE2 1 
ATOM   390  C CZ  . PHE A 1 58  ? 103.606 127.548 151.527 1.00 61.81  ? 58  PHE A CZ  1 
ATOM   391  N N   . THR A 1 59  ? 104.099 120.955 154.762 1.00 60.81  ? 59  THR A N   1 
ATOM   392  C CA  . THR A 1 59  ? 103.746 119.694 155.393 1.00 59.82  ? 59  THR A CA  1 
ATOM   393  C C   . THR A 1 59  ? 104.840 119.117 156.275 1.00 64.88  ? 59  THR A C   1 
ATOM   394  O O   . THR A 1 59  ? 104.532 118.321 157.166 1.00 70.93  ? 59  THR A O   1 
ATOM   395  C CB  . THR A 1 59  ? 103.375 118.649 154.334 1.00 60.47  ? 59  THR A CB  1 
ATOM   396  O OG1 . THR A 1 59  ? 104.449 118.517 153.398 1.00 67.55  ? 59  THR A OG1 1 
ATOM   397  C CG2 . THR A 1 59  ? 102.119 119.068 153.600 1.00 66.46  ? 59  THR A CG2 1 
ATOM   398  N N   . ARG A 1 60  ? 106.094 119.493 156.058 1.00 62.03  ? 60  ARG A N   1 
ATOM   399  C CA  . ARG A 1 60  ? 107.188 118.926 156.827 1.00 64.01  ? 60  ARG A CA  1 
ATOM   400  C C   . ARG A 1 60  ? 107.181 119.468 158.253 1.00 67.51  ? 60  ARG A C   1 
ATOM   401  O O   . ARG A 1 60  ? 106.636 120.536 158.540 1.00 67.61  ? 60  ARG A O   1 
ATOM   402  C CB  . ARG A 1 60  ? 108.521 119.232 156.151 1.00 62.36  ? 60  ARG A CB  1 
ATOM   403  C CG  . ARG A 1 60  ? 109.550 118.134 156.288 1.00 69.20  ? 60  ARG A CG  1 
ATOM   404  C CD  . ARG A 1 60  ? 110.899 118.601 155.795 1.00 64.45  ? 60  ARG A CD  1 
ATOM   405  N NE  . ARG A 1 60  ? 111.228 119.919 156.316 1.00 58.83  ? 60  ARG A NE  1 
ATOM   406  C CZ  . ARG A 1 60  ? 112.066 120.136 157.318 1.00 60.92  ? 60  ARG A CZ  1 
ATOM   407  N NH1 . ARG A 1 60  ? 112.682 119.140 157.931 1.00 58.88  ? 60  ARG A NH1 1 
ATOM   408  N NH2 . ARG A 1 60  ? 112.290 121.383 157.717 1.00 68.31  ? 60  ARG A NH2 1 
ATOM   409  N N   . ASP A 1 61  ? 107.795 118.708 159.157 1.00 77.59  ? 61  ASP A N   1 
ATOM   410  C CA  . ASP A 1 61  ? 107.937 119.100 160.554 1.00 77.98  ? 61  ASP A CA  1 
ATOM   411  C C   . ASP A 1 61  ? 109.328 119.683 160.754 1.00 82.36  ? 61  ASP A C   1 
ATOM   412  O O   . ASP A 1 61  ? 110.329 119.013 160.485 1.00 85.63  ? 61  ASP A O   1 
ATOM   413  C CB  . ASP A 1 61  ? 107.716 117.907 161.484 1.00 77.35  ? 61  ASP A CB  1 
ATOM   414  C CG  . ASP A 1 61  ? 107.489 118.322 162.929 1.00 83.53  ? 61  ASP A CG  1 
ATOM   415  O OD1 . ASP A 1 61  ? 107.970 119.400 163.333 1.00 81.74  ? 61  ASP A OD1 1 
ATOM   416  O OD2 . ASP A 1 61  ? 106.831 117.561 163.667 1.00 88.29  ? 61  ASP A OD2 1 
ATOM   417  N N   . ASP A 1 62  ? 109.388 120.918 161.241 1.00 75.27  ? 62  ASP A N   1 
ATOM   418  C CA  . ASP A 1 62  ? 110.631 121.668 161.359 1.00 73.63  ? 62  ASP A CA  1 
ATOM   419  C C   . ASP A 1 62  ? 110.925 122.079 162.800 1.00 75.81  ? 62  ASP A C   1 
ATOM   420  O O   . ASP A 1 62  ? 111.455 123.160 163.066 1.00 80.60  ? 62  ASP A O   1 
ATOM   421  C CB  . ASP A 1 62  ? 110.614 122.861 160.399 1.00 73.07  ? 62  ASP A CB  1 
ATOM   422  C CG  . ASP A 1 62  ? 109.663 123.981 160.825 1.00 81.68  ? 62  ASP A CG  1 
ATOM   423  O OD1 . ASP A 1 62  ? 109.234 124.056 161.993 1.00 84.78  ? 62  ASP A OD1 1 
ATOM   424  O OD2 . ASP A 1 62  ? 109.333 124.813 159.954 1.00 88.13  ? 62  ASP A OD2 1 
ATOM   425  N N   . SER A 1 63  ? 110.624 121.192 163.749 1.00 77.86  ? 63  SER A N   1 
ATOM   426  C CA  . SER A 1 63  ? 110.861 121.493 165.156 1.00 82.10  ? 63  SER A CA  1 
ATOM   427  C C   . SER A 1 63  ? 112.259 121.092 165.611 1.00 81.75  ? 63  SER A C   1 
ATOM   428  O O   . SER A 1 63  ? 112.697 121.518 166.685 1.00 83.53  ? 63  SER A O   1 
ATOM   429  C CB  . SER A 1 63  ? 109.809 120.800 166.023 1.00 83.64  ? 63  SER A CB  1 
ATOM   430  O OG  . SER A 1 63  ? 109.762 119.409 165.761 1.00 84.43  ? 63  SER A OG  1 
ATOM   431  N N   . VAL A 1 64  ? 112.966 120.279 164.835 1.00 75.49  ? 64  VAL A N   1 
ATOM   432  C CA  . VAL A 1 64  ? 114.310 119.831 165.187 1.00 78.41  ? 64  VAL A CA  1 
ATOM   433  C C   . VAL A 1 64  ? 115.310 120.643 164.369 1.00 80.53  ? 64  VAL A C   1 
ATOM   434  O O   . VAL A 1 64  ? 115.247 120.606 163.131 1.00 80.78  ? 64  VAL A O   1 
ATOM   435  C CB  . VAL A 1 64  ? 114.487 118.331 164.937 1.00 77.72  ? 64  VAL A CB  1 
ATOM   436  C CG1 . VAL A 1 64  ? 115.735 117.829 165.637 1.00 74.01  ? 64  VAL A CG1 1 
ATOM   437  C CG2 . VAL A 1 64  ? 113.263 117.570 165.411 1.00 75.30  ? 64  VAL A CG2 1 
ATOM   438  N N   . PRO A 1 65  ? 116.224 121.378 165.001 1.00 78.98  ? 65  PRO A N   1 
ATOM   439  C CA  . PRO A 1 65  ? 117.165 122.216 164.242 1.00 73.71  ? 65  PRO A CA  1 
ATOM   440  C C   . PRO A 1 65  ? 118.158 121.442 163.385 1.00 77.48  ? 65  PRO A C   1 
ATOM   441  O O   . PRO A 1 65  ? 118.323 121.753 162.201 1.00 82.93  ? 65  PRO A O   1 
ATOM   442  C CB  . PRO A 1 65  ? 117.889 123.004 165.340 1.00 71.92  ? 65  PRO A CB  1 
ATOM   443  C CG  . PRO A 1 65  ? 116.964 122.971 166.507 1.00 75.70  ? 65  PRO A CG  1 
ATOM   444  C CD  . PRO A 1 65  ? 116.303 121.634 166.446 1.00 76.46  ? 65  PRO A CD  1 
ATOM   445  N N   . GLU A 1 66  ? 118.837 120.450 163.966 1.00 75.31  ? 66  GLU A N   1 
ATOM   446  C CA  . GLU A 1 66  ? 119.896 119.759 163.235 1.00 73.60  ? 66  GLU A CA  1 
ATOM   447  C C   . GLU A 1 66  ? 119.347 119.028 162.017 1.00 75.39  ? 66  GLU A C   1 
ATOM   448  O O   . GLU A 1 66  ? 119.952 119.060 160.938 1.00 80.26  ? 66  GLU A O   1 
ATOM   449  C CB  . GLU A 1 66  ? 120.628 118.787 164.157 1.00 73.08  ? 66  GLU A CB  1 
ATOM   450  C CG  . GLU A 1 66  ? 120.932 119.349 165.530 1.00 79.66  ? 66  GLU A CG  1 
ATOM   451  C CD  . GLU A 1 66  ? 119.976 118.844 166.591 1.00 83.99  ? 66  GLU A CD  1 
ATOM   452  O OE1 . GLU A 1 66  ? 118.904 118.323 166.226 1.00 82.66  ? 66  GLU A OE1 1 
ATOM   453  O OE2 . GLU A 1 66  ? 120.296 118.970 167.790 1.00 85.52  ? 66  GLU A OE2 1 
ATOM   454  N N   . ASP A 1 67  ? 118.207 118.353 162.169 1.00 70.47  ? 67  ASP A N   1 
ATOM   455  C CA  . ASP A 1 67  ? 117.606 117.685 161.023 1.00 67.27  ? 67  ASP A CA  1 
ATOM   456  C C   . ASP A 1 67  ? 117.141 118.688 159.980 1.00 72.43  ? 67  ASP A C   1 
ATOM   457  O O   . ASP A 1 67  ? 117.190 118.397 158.780 1.00 78.55  ? 67  ASP A O   1 
ATOM   458  C CB  . ASP A 1 67  ? 116.452 116.796 161.475 1.00 71.85  ? 67  ASP A CB  1 
ATOM   459  C CG  . ASP A 1 67  ? 116.920 115.625 162.314 1.00 80.86  ? 67  ASP A CG  1 
ATOM   460  O OD1 . ASP A 1 67  ? 117.259 114.574 161.731 1.00 83.36  ? 67  ASP A OD1 1 
ATOM   461  O OD2 . ASP A 1 67  ? 116.959 115.755 163.554 1.00 77.77  ? 67  ASP A OD2 1 
ATOM   462  N N   . ASN A 1 68  ? 116.702 119.871 160.411 1.00 68.37  ? 68  ASN A N   1 
ATOM   463  C CA  . ASN A 1 68  ? 116.359 120.919 159.458 1.00 60.79  ? 68  ASN A CA  1 
ATOM   464  C C   . ASN A 1 68  ? 117.574 121.335 158.645 1.00 64.79  ? 68  ASN A C   1 
ATOM   465  O O   . ASN A 1 68  ? 117.488 121.486 157.423 1.00 70.67  ? 68  ASN A O   1 
ATOM   466  C CB  . ASN A 1 68  ? 115.774 122.121 160.189 1.00 59.29  ? 68  ASN A CB  1 
ATOM   467  C CG  . ASN A 1 68  ? 114.302 121.974 160.444 1.00 70.04  ? 68  ASN A CG  1 
ATOM   468  O OD1 . ASN A 1 68  ? 113.616 121.223 159.755 1.00 72.12  ? 68  ASN A OD1 1 
ATOM   469  N ND2 . ASN A 1 68  ? 113.802 122.687 161.442 1.00 71.94  ? 68  ASN A ND2 1 
ATOM   470  N N   . ILE A 1 69  ? 118.718 121.514 159.306 1.00 64.92  ? 69  ILE A N   1 
ATOM   471  C CA  . ILE A 1 69  ? 119.934 121.885 158.588 1.00 64.76  ? 69  ILE A CA  1 
ATOM   472  C C   . ILE A 1 69  ? 120.332 120.785 157.615 1.00 64.60  ? 69  ILE A C   1 
ATOM   473  O O   . ILE A 1 69  ? 120.719 121.055 156.471 1.00 71.78  ? 69  ILE A O   1 
ATOM   474  C CB  . ILE A 1 69  ? 121.070 122.196 159.578 1.00 61.07  ? 69  ILE A CB  1 
ATOM   475  C CG1 . ILE A 1 69  ? 120.631 123.267 160.571 1.00 62.55  ? 69  ILE A CG1 1 
ATOM   476  C CG2 . ILE A 1 69  ? 122.314 122.631 158.836 1.00 57.57  ? 69  ILE A CG2 1 
ATOM   477  C CD1 . ILE A 1 69  ? 120.650 124.651 160.010 1.00 66.61  ? 69  ILE A CD1 1 
ATOM   478  N N   . TRP A 1 70  ? 120.250 119.529 158.052 1.00 61.44  ? 70  TRP A N   1 
ATOM   479  C CA  . TRP A 1 70  ? 120.643 118.422 157.186 1.00 58.54  ? 70  TRP A CA  1 
ATOM   480  C C   . TRP A 1 70  ? 119.751 118.339 155.953 1.00 65.10  ? 70  TRP A C   1 
ATOM   481  O O   . TRP A 1 70  ? 120.239 118.209 154.823 1.00 71.99  ? 70  TRP A O   1 
ATOM   482  C CB  . TRP A 1 70  ? 120.607 117.111 157.967 1.00 59.18  ? 70  TRP A CB  1 
ATOM   483  C CG  . TRP A 1 70  ? 121.004 115.931 157.150 1.00 62.72  ? 70  TRP A CG  1 
ATOM   484  C CD1 . TRP A 1 70  ? 120.270 114.808 156.930 1.00 62.45  ? 70  TRP A CD1 1 
ATOM   485  C CD2 . TRP A 1 70  ? 122.233 115.753 156.439 1.00 68.20  ? 70  TRP A CD2 1 
ATOM   486  N NE1 . TRP A 1 70  ? 120.963 113.940 156.127 1.00 65.12  ? 70  TRP A NE1 1 
ATOM   487  C CE2 . TRP A 1 70  ? 122.172 114.499 155.812 1.00 65.99  ? 70  TRP A CE2 1 
ATOM   488  C CE3 . TRP A 1 70  ? 123.380 116.534 156.273 1.00 65.03  ? 70  TRP A CE3 1 
ATOM   489  C CZ2 . TRP A 1 70  ? 123.211 114.007 155.033 1.00 66.04  ? 70  TRP A CZ2 1 
ATOM   490  C CZ3 . TRP A 1 70  ? 124.407 116.045 155.500 1.00 64.16  ? 70  TRP A CZ3 1 
ATOM   491  C CH2 . TRP A 1 70  ? 124.317 114.794 154.889 1.00 67.85  ? 70  TRP A CH2 1 
ATOM   492  N N   . ARG A 1 71  ? 118.434 118.418 156.150 1.00 60.91  ? 71  ARG A N   1 
ATOM   493  C CA  . ARG A 1 71  ? 117.526 118.346 155.014 1.00 55.67  ? 71  ARG A CA  1 
ATOM   494  C C   . ARG A 1 71  ? 117.670 119.558 154.105 1.00 63.21  ? 71  ARG A C   1 
ATOM   495  O O   . ARG A 1 71  ? 117.542 119.429 152.884 1.00 65.05  ? 71  ARG A O   1 
ATOM   496  C CB  . ARG A 1 71  ? 116.089 118.199 155.499 1.00 50.98  ? 71  ARG A CB  1 
ATOM   497  C CG  . ARG A 1 71  ? 115.832 116.889 156.212 1.00 57.90  ? 71  ARG A CG  1 
ATOM   498  C CD  . ARG A 1 71  ? 114.715 116.117 155.542 1.00 63.09  ? 71  ARG A CD  1 
ATOM   499  N NE  . ARG A 1 71  ? 114.883 116.065 154.095 1.00 70.80  ? 71  ARG A NE  1 
ATOM   500  C CZ  . ARG A 1 71  ? 113.948 115.664 153.246 1.00 74.31  ? 71  ARG A CZ  1 
ATOM   501  N NH1 . ARG A 1 71  ? 112.755 115.273 153.665 1.00 72.61  ? 71  ARG A NH1 1 
ATOM   502  N NH2 . ARG A 1 71  ? 114.214 115.656 151.943 1.00 62.85  ? 71  ARG A NH2 1 
ATOM   503  N N   . GLY A 1 72  ? 117.946 120.735 154.669 1.00 56.95  ? 72  GLY A N   1 
ATOM   504  C CA  . GLY A 1 72  ? 118.209 121.891 153.833 1.00 56.35  ? 72  GLY A CA  1 
ATOM   505  C C   . GLY A 1 72  ? 119.445 121.715 152.975 1.00 63.12  ? 72  GLY A C   1 
ATOM   506  O O   . GLY A 1 72  ? 119.457 122.097 151.804 1.00 67.40  ? 72  GLY A O   1 
ATOM   507  N N   . ILE A 1 73  ? 120.504 121.137 153.546 1.00 59.05  ? 73  ILE A N   1 
ATOM   508  C CA  . ILE A 1 73  ? 121.711 120.867 152.769 1.00 51.60  ? 73  ILE A CA  1 
ATOM   509  C C   . ILE A 1 73  ? 121.412 119.886 151.644 1.00 55.44  ? 73  ILE A C   1 
ATOM   510  O O   . ILE A 1 73  ? 121.844 120.076 150.498 1.00 66.05  ? 73  ILE A O   1 
ATOM   511  C CB  . ILE A 1 73  ? 122.832 120.351 153.687 1.00 48.30  ? 73  ILE A CB  1 
ATOM   512  C CG1 . ILE A 1 73  ? 123.389 121.494 154.530 1.00 57.04  ? 73  ILE A CG1 1 
ATOM   513  C CG2 . ILE A 1 73  ? 123.936 119.718 152.877 1.00 58.17  ? 73  ILE A CG2 1 
ATOM   514  C CD1 . ILE A 1 73  ? 124.295 121.041 155.639 1.00 59.96  ? 73  ILE A CD1 1 
ATOM   515  N N   . LEU A 1 74  ? 120.665 118.823 151.950 1.00 50.51  ? 74  LEU A N   1 
ATOM   516  C CA  . LEU A 1 74  ? 120.313 117.850 150.918 1.00 50.69  ? 74  LEU A CA  1 
ATOM   517  C C   . LEU A 1 74  ? 119.497 118.492 149.803 1.00 56.70  ? 74  LEU A C   1 
ATOM   518  O O   . LEU A 1 74  ? 119.732 118.229 148.618 1.00 61.58  ? 74  LEU A O   1 
ATOM   519  C CB  . LEU A 1 74  ? 119.544 116.687 151.536 1.00 50.04  ? 74  LEU A CB  1 
ATOM   520  C CG  . LEU A 1 74  ? 120.338 115.812 152.496 1.00 53.84  ? 74  LEU A CG  1 
ATOM   521  C CD1 . LEU A 1 74  ? 119.549 114.570 152.844 1.00 57.87  ? 74  LEU A CD1 1 
ATOM   522  C CD2 . LEU A 1 74  ? 121.667 115.450 151.878 1.00 55.04  ? 74  LEU A CD2 1 
ATOM   523  N N   . SER A 1 75  ? 118.531 119.337 150.163 1.00 44.96  ? 75  SER A N   1 
ATOM   524  C CA  . SER A 1 75  ? 117.707 119.990 149.154 1.00 49.13  ? 75  SER A CA  1 
ATOM   525  C C   . SER A 1 75  ? 118.520 120.966 148.316 1.00 48.88  ? 75  SER A C   1 
ATOM   526  O O   . SER A 1 75  ? 118.315 121.069 147.101 1.00 54.41  ? 75  SER A O   1 
ATOM   527  C CB  . SER A 1 75  ? 116.539 120.705 149.819 1.00 53.01  ? 75  SER A CB  1 
ATOM   528  O OG  . SER A 1 75  ? 115.686 121.274 148.846 1.00 65.27  ? 75  SER A OG  1 
ATOM   529  N N   . VAL A 1 76  ? 119.439 121.701 148.944 1.00 43.19  ? 76  VAL A N   1 
ATOM   530  C CA  . VAL A 1 76  ? 120.297 122.611 148.194 1.00 42.24  ? 76  VAL A CA  1 
ATOM   531  C C   . VAL A 1 76  ? 121.137 121.837 147.192 1.00 46.75  ? 76  VAL A C   1 
ATOM   532  O O   . VAL A 1 76  ? 121.304 122.260 146.045 1.00 57.95  ? 76  VAL A O   1 
ATOM   533  C CB  . VAL A 1 76  ? 121.173 123.434 149.155 1.00 44.97  ? 76  VAL A CB  1 
ATOM   534  C CG1 . VAL A 1 76  ? 122.427 123.910 148.454 1.00 47.17  ? 76  VAL A CG1 1 
ATOM   535  C CG2 . VAL A 1 76  ? 120.392 124.604 149.705 1.00 45.00  ? 76  VAL A CG2 1 
ATOM   536  N N   . ILE A 1 77  ? 121.664 120.682 147.601 1.00 51.07  ? 77  ILE A N   1 
ATOM   537  C CA  . ILE A 1 77  ? 122.450 119.866 146.678 1.00 55.19  ? 77  ILE A CA  1 
ATOM   538  C C   . ILE A 1 77  ? 121.583 119.368 145.528 1.00 53.71  ? 77  ILE A C   1 
ATOM   539  O O   . ILE A 1 77  ? 121.989 119.409 144.359 1.00 61.65  ? 77  ILE A O   1 
ATOM   540  C CB  . ILE A 1 77  ? 123.119 118.705 147.431 1.00 45.79  ? 77  ILE A CB  1 
ATOM   541  C CG1 . ILE A 1 77  ? 124.356 119.207 148.172 1.00 54.85  ? 77  ILE A CG1 1 
ATOM   542  C CG2 . ILE A 1 77  ? 123.488 117.597 146.477 1.00 40.17  ? 77  ILE A CG2 1 
ATOM   543  C CD1 . ILE A 1 77  ? 125.023 118.160 149.005 1.00 55.04  ? 77  ILE A CD1 1 
ATOM   544  N N   . PHE A 1 78  ? 120.372 118.902 145.835 1.00 38.59  ? 78  PHE A N   1 
ATOM   545  C CA  . PHE A 1 78  ? 119.492 118.391 144.787 1.00 37.53  ? 78  PHE A CA  1 
ATOM   546  C C   . PHE A 1 78  ? 119.149 119.475 143.773 1.00 41.20  ? 78  PHE A C   1 
ATOM   547  O O   . PHE A 1 78  ? 119.196 119.245 142.557 1.00 57.03  ? 78  PHE A O   1 
ATOM   548  C CB  . PHE A 1 78  ? 118.223 117.819 145.412 1.00 38.02  ? 78  PHE A CB  1 
ATOM   549  C CG  . PHE A 1 78  ? 117.185 117.416 144.414 1.00 40.36  ? 78  PHE A CG  1 
ATOM   550  C CD1 . PHE A 1 78  ? 117.498 116.566 143.378 1.00 52.45  ? 78  PHE A CD1 1 
ATOM   551  C CD2 . PHE A 1 78  ? 115.891 117.876 144.522 1.00 46.01  ? 78  PHE A CD2 1 
ATOM   552  C CE1 . PHE A 1 78  ? 116.542 116.192 142.463 1.00 53.50  ? 78  PHE A CE1 1 
ATOM   553  C CE2 . PHE A 1 78  ? 114.932 117.503 143.609 1.00 47.30  ? 78  PHE A CE2 1 
ATOM   554  C CZ  . PHE A 1 78  ? 115.258 116.662 142.580 1.00 43.38  ? 78  PHE A CZ  1 
ATOM   555  N N   . PHE A 1 79  ? 118.819 120.671 144.246 1.00 38.87  ? 79  PHE A N   1 
ATOM   556  C CA  . PHE A 1 79  ? 118.422 121.708 143.308 1.00 39.73  ? 79  PHE A CA  1 
ATOM   557  C C   . PHE A 1 79  ? 119.608 122.367 142.626 1.00 36.54  ? 79  PHE A C   1 
ATOM   558  O O   . PHE A 1 79  ? 119.448 122.904 141.528 1.00 41.19  ? 79  PHE A O   1 
ATOM   559  C CB  . PHE A 1 79  ? 117.528 122.719 144.013 1.00 40.66  ? 79  PHE A CB  1 
ATOM   560  C CG  . PHE A 1 79  ? 116.163 122.182 144.281 1.00 44.35  ? 79  PHE A CG  1 
ATOM   561  C CD1 . PHE A 1 79  ? 115.268 122.011 143.249 1.00 41.29  ? 79  PHE A CD1 1 
ATOM   562  C CD2 . PHE A 1 79  ? 115.797 121.777 145.545 1.00 50.75  ? 79  PHE A CD2 1 
ATOM   563  C CE1 . PHE A 1 79  ? 114.024 121.486 143.479 1.00 50.57  ? 79  PHE A CE1 1 
ATOM   564  C CE2 . PHE A 1 79  ? 114.552 121.249 145.779 1.00 45.66  ? 79  PHE A CE2 1 
ATOM   565  C CZ  . PHE A 1 79  ? 113.667 121.102 144.742 1.00 51.37  ? 79  PHE A CZ  1 
ATOM   566  N N   . PHE A 1 80  ? 120.808 122.278 143.200 1.00 33.81  ? 80  PHE A N   1 
ATOM   567  C CA  . PHE A 1 80  ? 121.984 122.618 142.414 1.00 37.44  ? 80  PHE A CA  1 
ATOM   568  C C   . PHE A 1 80  ? 122.219 121.601 141.311 1.00 39.75  ? 80  PHE A C   1 
ATOM   569  O O   . PHE A 1 80  ? 122.676 121.966 140.227 1.00 47.20  ? 80  PHE A O   1 
ATOM   570  C CB  . PHE A 1 80  ? 123.224 122.725 143.290 1.00 37.95  ? 80  PHE A CB  1 
ATOM   571  C CG  . PHE A 1 80  ? 124.410 123.279 142.566 1.00 40.93  ? 80  PHE A CG  1 
ATOM   572  C CD1 . PHE A 1 80  ? 124.502 124.628 142.300 1.00 39.07  ? 80  PHE A CD1 1 
ATOM   573  C CD2 . PHE A 1 80  ? 125.420 122.451 142.131 1.00 44.70  ? 80  PHE A CD2 1 
ATOM   574  C CE1 . PHE A 1 80  ? 125.581 125.142 141.630 1.00 41.76  ? 80  PHE A CE1 1 
ATOM   575  C CE2 . PHE A 1 80  ? 126.505 122.963 141.460 1.00 47.48  ? 80  PHE A CE2 1 
ATOM   576  C CZ  . PHE A 1 80  ? 126.584 124.309 141.210 1.00 43.55  ? 80  PHE A CZ  1 
ATOM   577  N N   . LEU A 1 81  ? 121.915 120.326 141.559 1.00 37.15  ? 81  LEU A N   1 
ATOM   578  C CA  . LEU A 1 81  ? 121.981 119.345 140.481 1.00 35.55  ? 81  LEU A CA  1 
ATOM   579  C C   . LEU A 1 81  ? 120.990 119.683 139.375 1.00 39.12  ? 81  LEU A C   1 
ATOM   580  O O   . LEU A 1 81  ? 121.303 119.555 138.187 1.00 49.81  ? 81  LEU A O   1 
ATOM   581  C CB  . LEU A 1 81  ? 121.715 117.942 141.021 1.00 39.74  ? 81  LEU A CB  1 
ATOM   582  C CG  . LEU A 1 81  ? 122.792 117.314 141.899 1.00 43.80  ? 81  LEU A CG  1 
ATOM   583  C CD1 . LEU A 1 81  ? 122.585 115.818 141.981 1.00 46.46  ? 81  LEU A CD1 1 
ATOM   584  C CD2 . LEU A 1 81  ? 124.168 117.634 141.369 1.00 45.43  ? 81  LEU A CD2 1 
ATOM   585  N N   . ILE A 1 82  ? 119.785 120.111 139.749 1.00 38.76  ? 82  ILE A N   1 
ATOM   586  C CA  . ILE A 1 82  ? 118.795 120.495 138.742 1.00 30.97  ? 82  ILE A CA  1 
ATOM   587  C C   . ILE A 1 82  ? 119.262 121.719 137.953 1.00 36.74  ? 82  ILE A C   1 
ATOM   588  O O   . ILE A 1 82  ? 119.135 121.770 136.721 1.00 44.34  ? 82  ILE A O   1 
ATOM   589  C CB  . ILE A 1 82  ? 117.427 120.725 139.407 1.00 40.01  ? 82  ILE A CB  1 
ATOM   590  C CG1 . ILE A 1 82  ? 116.639 119.419 139.441 1.00 39.82  ? 82  ILE A CG1 1 
ATOM   591  C CG2 . ILE A 1 82  ? 116.643 121.802 138.684 1.00 38.30  ? 82  ILE A CG2 1 
ATOM   592  C CD1 . ILE A 1 82  ? 115.311 119.537 140.131 1.00 49.82  ? 82  ILE A CD1 1 
ATOM   593  N N   . ILE A 1 83  ? 119.817 122.718 138.642 1.00 48.30  ? 83  ILE A N   1 
ATOM   594  C CA  . ILE A 1 83  ? 120.366 123.885 137.953 1.00 41.94  ? 83  ILE A CA  1 
ATOM   595  C C   . ILE A 1 83  ? 121.498 123.473 137.019 1.00 42.06  ? 83  ILE A C   1 
ATOM   596  O O   . ILE A 1 83  ? 121.636 124.008 135.914 1.00 48.35  ? 83  ILE A O   1 
ATOM   597  C CB  . ILE A 1 83  ? 120.829 124.939 138.975 1.00 43.02  ? 83  ILE A CB  1 
ATOM   598  C CG1 . ILE A 1 83  ? 119.684 125.889 139.313 1.00 42.39  ? 83  ILE A CG1 1 
ATOM   599  C CG2 . ILE A 1 83  ? 122.018 125.714 138.450 1.00 40.59  ? 83  ILE A CG2 1 
ATOM   600  C CD1 . ILE A 1 83  ? 119.268 126.759 138.162 1.00 42.51  ? 83  ILE A CD1 1 
ATOM   601  N N   . SER A 1 84  ? 122.324 122.518 137.446 1.00 47.57  ? 84  SER A N   1 
ATOM   602  C CA  . SER A 1 84  ? 123.395 122.016 136.593 1.00 47.91  ? 84  SER A CA  1 
ATOM   603  C C   . SER A 1 84  ? 122.838 121.344 135.348 1.00 45.44  ? 84  SER A C   1 
ATOM   604  O O   . SER A 1 84  ? 123.380 121.510 134.251 1.00 47.54  ? 84  SER A O   1 
ATOM   605  C CB  . SER A 1 84  ? 124.271 121.045 137.376 1.00 43.98  ? 84  SER A CB  1 
ATOM   606  O OG  . SER A 1 84  ? 123.591 119.829 137.599 1.00 57.77  ? 84  SER A OG  1 
ATOM   607  N N   . VAL A 1 85  ? 121.766 120.568 135.503 1.00 41.26  ? 85  VAL A N   1 
ATOM   608  C CA  . VAL A 1 85  ? 121.094 119.985 134.345 1.00 38.49  ? 85  VAL A CA  1 
ATOM   609  C C   . VAL A 1 85  ? 120.647 121.081 133.391 1.00 43.46  ? 85  VAL A C   1 
ATOM   610  O O   . VAL A 1 85  ? 120.769 120.952 132.168 1.00 48.80  ? 85  VAL A O   1 
ATOM   611  C CB  . VAL A 1 85  ? 119.908 119.114 134.797 1.00 39.60  ? 85  VAL A CB  1 
ATOM   612  C CG1 . VAL A 1 85  ? 118.848 119.056 133.724 1.00 40.07  ? 85  VAL A CG1 1 
ATOM   613  C CG2 . VAL A 1 85  ? 120.376 117.725 135.118 1.00 42.03  ? 85  VAL A CG2 1 
ATOM   614  N N   . LEU A 1 86  ? 120.129 122.179 133.937 1.00 54.41  ? 86  LEU A N   1 
ATOM   615  C CA  . LEU A 1 86  ? 119.619 123.247 133.083 1.00 55.56  ? 86  LEU A CA  1 
ATOM   616  C C   . LEU A 1 86  ? 120.740 124.006 132.377 1.00 52.18  ? 86  LEU A C   1 
ATOM   617  O O   . LEU A 1 86  ? 120.579 124.414 131.222 1.00 56.02  ? 86  LEU A O   1 
ATOM   618  C CB  . LEU A 1 86  ? 118.758 124.207 133.900 1.00 49.25  ? 86  LEU A CB  1 
ATOM   619  C CG  . LEU A 1 86  ? 117.353 123.713 134.228 1.00 43.84  ? 86  LEU A CG  1 
ATOM   620  C CD1 . LEU A 1 86  ? 116.601 124.770 134.989 1.00 47.55  ? 86  LEU A CD1 1 
ATOM   621  C CD2 . LEU A 1 86  ? 116.615 123.356 132.962 1.00 49.73  ? 86  LEU A CD2 1 
ATOM   622  N N   . ALA A 1 87  ? 121.875 124.213 133.041 1.00 46.89  ? 87  ALA A N   1 
ATOM   623  C CA  . ALA A 1 87  ? 122.849 125.191 132.564 1.00 49.02  ? 87  ALA A CA  1 
ATOM   624  C C   . ALA A 1 87  ? 124.239 124.638 132.293 1.00 52.44  ? 87  ALA A C   1 
ATOM   625  O O   . ALA A 1 87  ? 124.870 125.044 131.318 1.00 58.58  ? 87  ALA A O   1 
ATOM   626  C CB  . ALA A 1 87  ? 122.965 126.342 133.569 1.00 44.25  ? 87  ALA A CB  1 
ATOM   627  N N   . PHE A 1 88  ? 124.748 123.741 133.130 1.00 50.12  ? 88  PHE A N   1 
ATOM   628  C CA  . PHE A 1 88  ? 126.154 123.377 133.056 1.00 43.87  ? 88  PHE A CA  1 
ATOM   629  C C   . PHE A 1 88  ? 126.437 122.496 131.838 1.00 56.70  ? 88  PHE A C   1 
ATOM   630  O O   . PHE A 1 88  ? 125.541 121.820 131.329 1.00 67.07  ? 88  PHE A O   1 
ATOM   631  C CB  . PHE A 1 88  ? 126.583 122.661 134.331 1.00 37.56  ? 88  PHE A CB  1 
ATOM   632  C CG  . PHE A 1 88  ? 126.954 123.591 135.447 1.00 45.18  ? 88  PHE A CG  1 
ATOM   633  C CD1 . PHE A 1 88  ? 127.664 124.742 135.192 1.00 53.59  ? 88  PHE A CD1 1 
ATOM   634  C CD2 . PHE A 1 88  ? 126.610 123.307 136.748 1.00 46.54  ? 88  PHE A CD2 1 
ATOM   635  C CE1 . PHE A 1 88  ? 128.010 125.594 136.211 1.00 51.23  ? 88  PHE A CE1 1 
ATOM   636  C CE2 . PHE A 1 88  ? 126.953 124.154 137.768 1.00 48.87  ? 88  PHE A CE2 1 
ATOM   637  C CZ  . PHE A 1 88  ? 127.656 125.296 137.501 1.00 50.66  ? 88  PHE A CZ  1 
ATOM   638  N N   . PRO A 1 89  ? 127.672 122.504 131.340 1.00 52.67  ? 89  PRO A N   1 
ATOM   639  C CA  . PRO A 1 89  ? 128.018 121.675 130.182 1.00 48.96  ? 89  PRO A CA  1 
ATOM   640  C C   . PRO A 1 89  ? 128.162 120.205 130.546 1.00 55.63  ? 89  PRO A C   1 
ATOM   641  O O   . PRO A 1 89  ? 128.344 119.835 131.705 1.00 59.20  ? 89  PRO A O   1 
ATOM   642  C CB  . PRO A 1 89  ? 129.358 122.257 129.728 1.00 52.72  ? 89  PRO A CB  1 
ATOM   643  C CG  . PRO A 1 89  ? 129.931 122.849 130.944 1.00 51.00  ? 89  PRO A CG  1 
ATOM   644  C CD  . PRO A 1 89  ? 128.777 123.400 131.714 1.00 49.77  ? 89  PRO A CD  1 
ATOM   645  N N   . ASN A 1 90  ? 128.094 119.360 129.515 1.00 60.41  ? 90  ASN A N   1 
ATOM   646  C CA  . ASN A 1 90  ? 128.045 117.915 129.699 1.00 57.25  ? 90  ASN A CA  1 
ATOM   647  C C   . ASN A 1 90  ? 129.310 117.202 129.230 1.00 59.73  ? 90  ASN A C   1 
ATOM   648  O O   . ASN A 1 90  ? 129.280 115.991 129.004 1.00 64.60  ? 90  ASN A O   1 
ATOM   649  C CB  . ASN A 1 90  ? 126.819 117.333 128.995 1.00 57.08  ? 90  ASN A CB  1 
ATOM   650  C CG  . ASN A 1 90  ? 126.947 117.340 127.492 1.00 57.84  ? 90  ASN A CG  1 
ATOM   651  O OD1 . ASN A 1 90  ? 127.564 116.456 126.905 1.00 53.69  ? 90  ASN A OD1 1 
ATOM   652  N ND2 . ASN A 1 90  ? 126.354 118.340 126.856 1.00 64.20  ? 90  ASN A ND2 1 
ATOM   653  N N   . GLY A 1 91  ? 130.420 117.918 129.085 1.00 54.40  ? 91  GLY A N   1 
ATOM   654  C CA  . GLY A 1 91  ? 131.688 117.289 128.795 1.00 51.09  ? 91  GLY A CA  1 
ATOM   655  C C   . GLY A 1 91  ? 131.747 116.686 127.407 1.00 53.22  ? 91  GLY A C   1 
ATOM   656  O O   . GLY A 1 91  ? 130.942 117.008 126.531 1.00 58.40  ? 91  GLY A O   1 
ATOM   657  N N   . PRO A 1 92  ? 132.710 115.792 127.180 1.00 55.44  ? 92  PRO A N   1 
ATOM   658  C CA  . PRO A 1 92  ? 132.823 115.121 125.885 1.00 61.65  ? 92  PRO A CA  1 
ATOM   659  C C   . PRO A 1 92  ? 131.963 113.878 125.747 1.00 65.33  ? 92  PRO A C   1 
ATOM   660  O O   . PRO A 1 92  ? 132.091 113.169 124.745 1.00 71.14  ? 92  PRO A O   1 
ATOM   661  C CB  . PRO A 1 92  ? 134.308 114.748 125.847 1.00 60.00  ? 92  PRO A CB  1 
ATOM   662  C CG  . PRO A 1 92  ? 134.624 114.449 127.264 1.00 56.43  ? 92  PRO A CG  1 
ATOM   663  C CD  . PRO A 1 92  ? 133.737 115.322 128.122 1.00 52.61  ? 92  PRO A CD  1 
ATOM   664  N N   . PHE A 1 93  ? 131.105 113.599 126.718 1.00 53.95  ? 93  PHE A N   1 
ATOM   665  C CA  . PHE A 1 93  ? 130.336 112.369 126.770 1.00 52.90  ? 93  PHE A CA  1 
ATOM   666  C C   . PHE A 1 93  ? 128.865 112.661 126.522 1.00 62.86  ? 93  PHE A C   1 
ATOM   667  O O   . PHE A 1 93  ? 128.351 113.717 126.898 1.00 69.08  ? 93  PHE A O   1 
ATOM   668  C CB  . PHE A 1 93  ? 130.511 111.681 128.123 1.00 49.63  ? 93  PHE A CB  1 
ATOM   669  C CG  . PHE A 1 93  ? 131.881 111.119 128.342 1.00 53.43  ? 93  PHE A CG  1 
ATOM   670  C CD1 . PHE A 1 93  ? 132.743 110.932 127.283 1.00 58.10  ? 93  PHE A CD1 1 
ATOM   671  C CD2 . PHE A 1 93  ? 132.305 110.774 129.605 1.00 59.71  ? 93  PHE A CD2 1 
ATOM   672  C CE1 . PHE A 1 93  ? 134.001 110.415 127.479 1.00 53.59  ? 93  PHE A CE1 1 
ATOM   673  C CE2 . PHE A 1 93  ? 133.562 110.255 129.803 1.00 61.03  ? 93  PHE A CE2 1 
ATOM   674  C CZ  . PHE A 1 93  ? 134.409 110.076 128.738 1.00 59.41  ? 93  PHE A CZ  1 
ATOM   675  N N   . THR A 1 94  ? 128.188 111.709 125.880 1.00 68.05  ? 94  THR A N   1 
ATOM   676  C CA  . THR A 1 94  ? 126.782 111.889 125.545 1.00 62.51  ? 94  THR A CA  1 
ATOM   677  C C   . THR A 1 94  ? 125.948 110.646 125.826 1.00 65.48  ? 94  THR A C   1 
ATOM   678  O O   . THR A 1 94  ? 124.825 110.543 125.322 1.00 77.92  ? 94  THR A O   1 
ATOM   679  C CB  . THR A 1 94  ? 126.617 112.278 124.079 1.00 67.08  ? 94  THR A CB  1 
ATOM   680  O OG1 . THR A 1 94  ? 125.229 112.475 123.794 1.00 71.09  ? 94  THR A OG1 1 
ATOM   681  C CG2 . THR A 1 94  ? 127.165 111.189 123.176 1.00 66.82  ? 94  THR A CG2 1 
ATOM   682  N N   . ARG A 1 95  ? 126.461 109.701 126.602 1.00 60.08  ? 95  ARG A N   1 
ATOM   683  C CA  . ARG A 1 95  ? 125.687 108.540 127.005 1.00 56.68  ? 95  ARG A CA  1 
ATOM   684  C C   . ARG A 1 95  ? 125.820 108.329 128.504 1.00 63.08  ? 95  ARG A C   1 
ATOM   685  O O   . ARG A 1 95  ? 126.868 108.622 129.085 1.00 69.96  ? 95  ARG A O   1 
ATOM   686  C CB  . ARG A 1 95  ? 126.142 107.275 126.267 1.00 57.00  ? 95  ARG A CB  1 
ATOM   687  C CG  . ARG A 1 95  ? 125.588 107.126 124.862 1.00 61.28  ? 95  ARG A CG  1 
ATOM   688  C CD  . ARG A 1 95  ? 125.599 105.666 124.461 1.00 61.44  ? 95  ARG A CD  1 
ATOM   689  N NE  . ARG A 1 95  ? 125.118 105.429 123.108 1.00 59.72  ? 95  ARG A NE  1 
ATOM   690  C CZ  . ARG A 1 95  ? 123.845 105.455 122.746 1.00 66.78  ? 95  ARG A CZ  1 
ATOM   691  N NH1 . ARG A 1 95  ? 122.885 105.739 123.610 1.00 73.25  ? 95  ARG A NH1 1 
ATOM   692  N NH2 . ARG A 1 95  ? 123.524 105.185 121.484 1.00 67.57  ? 95  ARG A NH2 1 
ATOM   693  N N   . PRO A 1 96  ? 124.770 107.829 129.162 1.00 56.03  ? 96  PRO A N   1 
ATOM   694  C CA  . PRO A 1 96  ? 123.450 107.469 128.630 1.00 59.91  ? 96  PRO A CA  1 
ATOM   695  C C   . PRO A 1 96  ? 122.621 108.690 128.262 1.00 67.68  ? 96  PRO A C   1 
ATOM   696  O O   . PRO A 1 96  ? 121.719 108.621 127.437 1.00 70.17  ? 96  PRO A O   1 
ATOM   697  C CB  . PRO A 1 96  ? 122.824 106.693 129.788 1.00 56.73  ? 96  PRO A CB  1 
ATOM   698  C CG  . PRO A 1 96  ? 123.427 107.311 131.000 1.00 58.14  ? 96  PRO A CG  1 
ATOM   699  C CD  . PRO A 1 96  ? 124.846 107.604 130.613 1.00 57.59  ? 96  PRO A CD  1 
ATOM   700  N N   . HIS A 1 97  ? 122.930 109.837 128.863 1.00 61.79  ? 97  HIS A N   1 
ATOM   701  C CA  . HIS A 1 97  ? 122.214 111.071 128.600 1.00 53.63  ? 97  HIS A CA  1 
ATOM   702  C C   . HIS A 1 97  ? 123.111 112.204 129.054 1.00 61.09  ? 97  HIS A C   1 
ATOM   703  O O   . HIS A 1 97  ? 123.755 112.074 130.102 1.00 71.85  ? 97  HIS A O   1 
ATOM   704  C CB  . HIS A 1 97  ? 120.878 111.110 129.345 1.00 59.05  ? 97  HIS A CB  1 
ATOM   705  C CG  . HIS A 1 97  ? 119.888 112.071 128.767 1.00 59.50  ? 97  HIS A CG  1 
ATOM   706  N ND1 . HIS A 1 97  ? 119.417 113.161 129.463 1.00 69.19  ? 97  HIS A ND1 1 
ATOM   707  C CD2 . HIS A 1 97  ? 119.275 112.102 127.562 1.00 61.89  ? 97  HIS A CD2 1 
ATOM   708  C CE1 . HIS A 1 97  ? 118.561 113.826 128.710 1.00 67.38  ? 97  HIS A CE1 1 
ATOM   709  N NE2 . HIS A 1 97  ? 118.456 113.203 127.551 1.00 58.07  ? 97  HIS A NE2 1 
ATOM   710  N N   . PRO A 1 98  ? 123.193 113.307 128.312 1.00 55.11  ? 98  PRO A N   1 
ATOM   711  C CA  . PRO A 1 98  ? 124.066 114.409 128.739 1.00 57.78  ? 98  PRO A CA  1 
ATOM   712  C C   . PRO A 1 98  ? 123.682 114.999 130.081 1.00 60.01  ? 98  PRO A C   1 
ATOM   713  O O   . PRO A 1 98  ? 124.533 115.611 130.739 1.00 67.26  ? 98  PRO A O   1 
ATOM   714  C CB  . PRO A 1 98  ? 123.910 115.435 127.611 1.00 59.48  ? 98  PRO A CB  1 
ATOM   715  C CG  . PRO A 1 98  ? 123.410 114.655 126.450 1.00 58.12  ? 98  PRO A CG  1 
ATOM   716  C CD  . PRO A 1 98  ? 122.546 113.586 127.024 1.00 58.24  ? 98  PRO A CD  1 
ATOM   717  N N   . ALA A 1 99  ? 122.428 114.839 130.508 1.00 50.99  ? 99  ALA A N   1 
ATOM   718  C CA  . ALA A 1 99  ? 122.016 115.360 131.805 1.00 51.02  ? 99  ALA A CA  1 
ATOM   719  C C   . ALA A 1 99  ? 122.800 114.711 132.935 1.00 56.16  ? 99  ALA A C   1 
ATOM   720  O O   . ALA A 1 99  ? 123.105 115.360 133.940 1.00 64.52  ? 99  ALA A O   1 
ATOM   721  C CB  . ALA A 1 99  ? 120.518 115.147 132.001 1.00 51.93  ? 99  ALA A CB  1 
ATOM   722  N N   . LEU A 1 100 ? 123.137 113.429 132.792 1.00 48.52  ? 100 LEU A N   1 
ATOM   723  C CA  . LEU A 1 100 ? 123.921 112.754 133.820 1.00 46.12  ? 100 LEU A CA  1 
ATOM   724  C C   . LEU A 1 100 ? 125.284 113.407 133.991 1.00 52.29  ? 100 LEU A C   1 
ATOM   725  O O   . LEU A 1 100 ? 125.745 113.622 135.118 1.00 65.30  ? 100 LEU A O   1 
ATOM   726  C CB  . LEU A 1 100 ? 124.071 111.279 133.466 1.00 42.02  ? 100 LEU A CB  1 
ATOM   727  C CG  . LEU A 1 100 ? 124.323 110.307 134.611 1.00 55.05  ? 100 LEU A CG  1 
ATOM   728  C CD1 . LEU A 1 100 ? 123.729 108.962 134.263 1.00 59.77  ? 100 LEU A CD1 1 
ATOM   729  C CD2 . LEU A 1 100 ? 125.805 110.169 134.886 1.00 51.24  ? 100 LEU A CD2 1 
ATOM   730  N N   . TRP A 1 101 ? 125.944 113.741 132.887 1.00 46.70  ? 101 TRP A N   1 
ATOM   731  C CA  . TRP A 1 101 ? 127.254 114.366 132.990 1.00 44.27  ? 101 TRP A CA  1 
ATOM   732  C C   . TRP A 1 101 ? 127.154 115.823 133.412 1.00 48.28  ? 101 TRP A C   1 
ATOM   733  O O   . TRP A 1 101 ? 128.071 116.339 134.058 1.00 56.74  ? 101 TRP A O   1 
ATOM   734  C CB  . TRP A 1 101 ? 127.999 114.206 131.671 1.00 47.24  ? 101 TRP A CB  1 
ATOM   735  C CG  . TRP A 1 101 ? 128.255 112.768 131.388 1.00 54.99  ? 101 TRP A CG  1 
ATOM   736  C CD1 . TRP A 1 101 ? 127.631 111.990 130.467 1.00 51.30  ? 101 TRP A CD1 1 
ATOM   737  C CD2 . TRP A 1 101 ? 129.184 111.919 132.068 1.00 54.94  ? 101 TRP A CD2 1 
ATOM   738  N NE1 . TRP A 1 101 ? 128.122 110.711 130.518 1.00 48.02  ? 101 TRP A NE1 1 
ATOM   739  C CE2 . TRP A 1 101 ? 129.078 110.644 131.494 1.00 52.44  ? 101 TRP A CE2 1 
ATOM   740  C CE3 . TRP A 1 101 ? 130.101 112.118 133.101 1.00 49.78  ? 101 TRP A CE3 1 
ATOM   741  C CZ2 . TRP A 1 101 ? 129.853 109.574 131.917 1.00 53.43  ? 101 TRP A CZ2 1 
ATOM   742  C CZ3 . TRP A 1 101 ? 130.867 111.055 133.518 1.00 50.40  ? 101 TRP A CZ3 1 
ATOM   743  C CH2 . TRP A 1 101 ? 130.740 109.799 132.929 1.00 50.25  ? 101 TRP A CH2 1 
ATOM   744  N N   . ARG A 1 102 ? 126.041 116.489 133.107 1.00 50.09  ? 102 ARG A N   1 
ATOM   745  C CA  . ARG A 1 102 ? 125.802 117.803 133.695 1.00 43.84  ? 102 ARG A CA  1 
ATOM   746  C C   . ARG A 1 102 ? 125.679 117.710 135.212 1.00 47.04  ? 102 ARG A C   1 
ATOM   747  O O   . ARG A 1 102 ? 126.204 118.560 135.938 1.00 54.05  ? 102 ARG A O   1 
ATOM   748  C CB  . ARG A 1 102 ? 124.550 118.425 133.091 1.00 44.53  ? 102 ARG A CB  1 
ATOM   749  C CG  . ARG A 1 102 ? 124.705 118.816 131.646 1.00 46.48  ? 102 ARG A CG  1 
ATOM   750  C CD  . ARG A 1 102 ? 123.382 119.213 131.046 1.00 49.95  ? 102 ARG A CD  1 
ATOM   751  N NE  . ARG A 1 102 ? 123.438 119.229 129.593 1.00 47.91  ? 102 ARG A NE  1 
ATOM   752  C CZ  . ARG A 1 102 ? 122.380 119.119 128.806 1.00 56.47  ? 102 ARG A CZ  1 
ATOM   753  N NH1 . ARG A 1 102 ? 121.164 118.980 129.303 1.00 61.25  ? 102 ARG A NH1 1 
ATOM   754  N NH2 . ARG A 1 102 ? 122.547 119.143 127.488 1.00 53.00  ? 102 ARG A NH2 1 
ATOM   755  N N   . MET A 1 103 ? 124.987 116.684 135.709 1.00 46.28  ? 103 MET A N   1 
ATOM   756  C CA  . MET A 1 103 ? 124.877 116.489 137.152 1.00 43.44  ? 103 MET A CA  1 
ATOM   757  C C   . MET A 1 103 ? 126.229 116.165 137.775 1.00 48.20  ? 103 MET A C   1 
ATOM   758  O O   . MET A 1 103 ? 126.538 116.626 138.879 1.00 56.72  ? 103 MET A O   1 
ATOM   759  C CB  . MET A 1 103 ? 123.872 115.384 137.458 1.00 35.74  ? 103 MET A CB  1 
ATOM   760  C CG  . MET A 1 103 ? 122.443 115.755 137.149 1.00 42.46  ? 103 MET A CG  1 
ATOM   761  S SD  . MET A 1 103 ? 121.333 114.341 137.151 1.00 62.87  ? 103 MET A SD  1 
ATOM   762  C CE  . MET A 1 103 ? 119.968 114.996 138.097 1.00 47.63  ? 103 MET A CE  1 
ATOM   763  N N   . VAL A 1 104 ? 127.044 115.361 137.090 1.00 45.72  ? 104 VAL A N   1 
ATOM   764  C CA  . VAL A 1 104 ? 128.386 115.073 137.591 1.00 35.32  ? 104 VAL A CA  1 
ATOM   765  C C   . VAL A 1 104 ? 129.217 116.349 137.656 1.00 44.65  ? 104 VAL A C   1 
ATOM   766  O O   . VAL A 1 104 ? 129.970 116.569 138.611 1.00 59.87  ? 104 VAL A O   1 
ATOM   767  C CB  . VAL A 1 104 ? 129.063 113.995 136.727 1.00 35.54  ? 104 VAL A CB  1 
ATOM   768  C CG1 . VAL A 1 104 ? 130.532 113.903 137.063 1.00 36.23  ? 104 VAL A CG1 1 
ATOM   769  C CG2 . VAL A 1 104 ? 128.393 112.658 136.942 1.00 42.77  ? 104 VAL A CG2 1 
ATOM   770  N N   . PHE A 1 105 ? 129.093 117.214 136.648 1.00 43.27  ? 105 PHE A N   1 
ATOM   771  C CA  . PHE A 1 105 ? 129.796 118.493 136.690 1.00 35.38  ? 105 PHE A CA  1 
ATOM   772  C C   . PHE A 1 105 ? 129.288 119.372 137.825 1.00 42.42  ? 105 PHE A C   1 
ATOM   773  O O   . PHE A 1 105 ? 130.068 120.095 138.455 1.00 40.91  ? 105 PHE A O   1 
ATOM   774  C CB  . PHE A 1 105 ? 129.657 119.217 135.356 1.00 36.34  ? 105 PHE A CB  1 
ATOM   775  C CG  . PHE A 1 105 ? 130.437 120.489 135.284 1.00 41.00  ? 105 PHE A CG  1 
ATOM   776  C CD1 . PHE A 1 105 ? 131.803 120.481 135.427 1.00 52.48  ? 105 PHE A CD1 1 
ATOM   777  C CD2 . PHE A 1 105 ? 129.803 121.692 135.097 1.00 42.14  ? 105 PHE A CD2 1 
ATOM   778  C CE1 . PHE A 1 105 ? 132.520 121.648 135.369 1.00 46.14  ? 105 PHE A CE1 1 
ATOM   779  C CE2 . PHE A 1 105 ? 130.519 122.859 135.040 1.00 41.17  ? 105 PHE A CE2 1 
ATOM   780  C CZ  . PHE A 1 105 ? 131.875 122.836 135.178 1.00 35.53  ? 105 PHE A CZ  1 
ATOM   781  N N   . GLY A 1 106 ? 127.982 119.352 138.081 1.00 44.32  ? 106 GLY A N   1 
ATOM   782  C CA  . GLY A 1 106 ? 127.454 120.096 139.213 1.00 34.33  ? 106 GLY A CA  1 
ATOM   783  C C   . GLY A 1 106 ? 128.021 119.608 140.530 1.00 44.67  ? 106 GLY A C   1 
ATOM   784  O O   . GLY A 1 106 ? 128.359 120.405 141.408 1.00 62.51  ? 106 GLY A O   1 
ATOM   785  N N   . LEU A 1 107 ? 128.148 118.290 140.679 1.00 42.92  ? 107 LEU A N   1 
ATOM   786  C CA  . LEU A 1 107 ? 128.799 117.738 141.863 1.00 35.41  ? 107 LEU A CA  1 
ATOM   787  C C   . LEU A 1 107 ? 130.254 118.182 141.947 1.00 45.13  ? 107 LEU A C   1 
ATOM   788  O O   . LEU A 1 107 ? 130.757 118.480 143.036 1.00 62.38  ? 107 LEU A O   1 
ATOM   789  C CB  . LEU A 1 107 ? 128.710 116.214 141.853 1.00 40.81  ? 107 LEU A CB  1 
ATOM   790  C CG  . LEU A 1 107 ? 127.358 115.588 142.174 1.00 43.21  ? 107 LEU A CG  1 
ATOM   791  C CD1 . LEU A 1 107 ? 127.481 114.081 142.206 1.00 47.03  ? 107 LEU A CD1 1 
ATOM   792  C CD2 . LEU A 1 107 ? 126.832 116.110 143.492 1.00 43.87  ? 107 LEU A CD2 1 
ATOM   793  N N   . SER A 1 108 ? 130.952 118.219 140.809 1.00 40.41  ? 108 SER A N   1 
ATOM   794  C CA  . SER A 1 108 ? 132.337 118.682 140.804 1.00 31.52  ? 108 SER A CA  1 
ATOM   795  C C   . SER A 1 108 ? 132.439 120.119 141.287 1.00 52.27  ? 108 SER A C   1 
ATOM   796  O O   . SER A 1 108 ? 133.331 120.458 142.071 1.00 61.79  ? 108 SER A O   1 
ATOM   797  C CB  . SER A 1 108 ? 132.930 118.566 139.405 1.00 34.57  ? 108 SER A CB  1 
ATOM   798  O OG  . SER A 1 108 ? 132.482 117.394 138.757 1.00 60.61  ? 108 SER A OG  1 
ATOM   799  N N   . VAL A 1 109 ? 131.543 120.984 140.814 1.00 44.75  ? 109 VAL A N   1 
ATOM   800  C CA  . VAL A 1 109 ? 131.566 122.380 141.237 1.00 31.59  ? 109 VAL A CA  1 
ATOM   801  C C   . VAL A 1 109 ? 131.256 122.493 142.723 1.00 40.72  ? 109 VAL A C   1 
ATOM   802  O O   . VAL A 1 109 ? 131.888 123.275 143.445 1.00 58.84  ? 109 VAL A O   1 
ATOM   803  C CB  . VAL A 1 109 ? 130.590 123.211 140.389 1.00 32.48  ? 109 VAL A CB  1 
ATOM   804  C CG1 . VAL A 1 109 ? 130.434 124.598 140.973 1.00 36.48  ? 109 VAL A CG1 1 
ATOM   805  C CG2 . VAL A 1 109 ? 131.078 123.292 138.962 1.00 45.98  ? 109 VAL A CG2 1 
ATOM   806  N N   . LEU A 1 110 ? 130.282 121.717 143.206 1.00 44.91  ? 110 LEU A N   1 
ATOM   807  C CA  . LEU A 1 110 ? 129.968 121.725 144.632 1.00 37.76  ? 110 LEU A CA  1 
ATOM   808  C C   . LEU A 1 110 ? 131.180 121.325 145.459 1.00 42.26  ? 110 LEU A C   1 
ATOM   809  O O   . LEU A 1 110 ? 131.496 121.961 146.470 1.00 53.34  ? 110 LEU A O   1 
ATOM   810  C CB  . LEU A 1 110 ? 128.805 120.780 144.921 1.00 40.11  ? 110 LEU A CB  1 
ATOM   811  C CG  . LEU A 1 110 ? 127.377 121.288 144.768 1.00 46.07  ? 110 LEU A CG  1 
ATOM   812  C CD1 . LEU A 1 110 ? 126.408 120.209 145.188 1.00 49.35  ? 110 LEU A CD1 1 
ATOM   813  C CD2 . LEU A 1 110 ? 127.167 122.525 145.590 1.00 50.03  ? 110 LEU A CD2 1 
ATOM   814  N N   . TYR A 1 111 ? 131.874 120.267 145.040 1.00 40.95  ? 111 TYR A N   1 
ATOM   815  C CA  . TYR A 1 111 ? 133.039 119.806 145.785 1.00 41.38  ? 111 TYR A CA  1 
ATOM   816  C C   . TYR A 1 111 ? 134.165 120.829 145.746 1.00 47.80  ? 111 TYR A C   1 
ATOM   817  O O   . TYR A 1 111 ? 134.850 121.044 146.752 1.00 60.37  ? 111 TYR A O   1 
ATOM   818  C CB  . TYR A 1 111 ? 133.519 118.467 145.239 1.00 35.82  ? 111 TYR A CB  1 
ATOM   819  C CG  . TYR A 1 111 ? 134.566 117.821 146.103 1.00 44.23  ? 111 TYR A CG  1 
ATOM   820  C CD1 . TYR A 1 111 ? 134.405 117.747 147.474 1.00 58.18  ? 111 TYR A CD1 1 
ATOM   821  C CD2 . TYR A 1 111 ? 135.715 117.285 145.552 1.00 47.51  ? 111 TYR A CD2 1 
ATOM   822  C CE1 . TYR A 1 111 ? 135.355 117.159 148.270 1.00 58.31  ? 111 TYR A CE1 1 
ATOM   823  C CE2 . TYR A 1 111 ? 136.671 116.697 146.343 1.00 43.26  ? 111 TYR A CE2 1 
ATOM   824  C CZ  . TYR A 1 111 ? 136.484 116.638 147.700 1.00 52.83  ? 111 TYR A CZ  1 
ATOM   825  O OH  . TYR A 1 111 ? 137.433 116.050 148.495 1.00 63.10  ? 111 TYR A OH  1 
ATOM   826  N N   . PHE A 1 112 ? 134.384 121.459 144.592 1.00 38.57  ? 112 PHE A N   1 
ATOM   827  C CA  . PHE A 1 112 ? 135.422 122.478 144.498 1.00 36.09  ? 112 PHE A CA  1 
ATOM   828  C C   . PHE A 1 112 ? 135.125 123.642 145.432 1.00 48.84  ? 112 PHE A C   1 
ATOM   829  O O   . PHE A 1 112 ? 136.021 124.131 146.130 1.00 55.58  ? 112 PHE A O   1 
ATOM   830  C CB  . PHE A 1 112 ? 135.554 122.940 143.044 1.00 34.33  ? 112 PHE A CB  1 
ATOM   831  C CG  . PHE A 1 112 ? 135.997 124.366 142.880 1.00 38.45  ? 112 PHE A CG  1 
ATOM   832  C CD1 . PHE A 1 112 ? 137.221 124.794 143.351 1.00 45.82  ? 112 PHE A CD1 1 
ATOM   833  C CD2 . PHE A 1 112 ? 135.194 125.272 142.219 1.00 42.13  ? 112 PHE A CD2 1 
ATOM   834  C CE1 . PHE A 1 112 ? 137.615 126.102 143.188 1.00 43.72  ? 112 PHE A CE1 1 
ATOM   835  C CE2 . PHE A 1 112 ? 135.591 126.577 142.053 1.00 46.57  ? 112 PHE A CE2 1 
ATOM   836  C CZ  . PHE A 1 112 ? 136.802 126.990 142.536 1.00 45.69  ? 112 PHE A CZ  1 
ATOM   837  N N   . LEU A 1 113 ? 133.869 124.088 145.482 1.00 50.37  ? 113 LEU A N   1 
ATOM   838  C CA  . LEU A 1 113 ? 133.515 125.173 146.393 1.00 37.94  ? 113 LEU A CA  1 
ATOM   839  C C   . LEU A 1 113 ? 133.665 124.748 147.847 1.00 44.31  ? 113 LEU A C   1 
ATOM   840  O O   . LEU A 1 113 ? 134.113 125.536 148.688 1.00 56.35  ? 113 LEU A O   1 
ATOM   841  C CB  . LEU A 1 113 ? 132.095 125.647 146.117 1.00 32.87  ? 113 LEU A CB  1 
ATOM   842  C CG  . LEU A 1 113 ? 131.885 126.269 144.745 1.00 30.86  ? 113 LEU A CG  1 
ATOM   843  C CD1 . LEU A 1 113 ? 130.443 126.657 144.593 1.00 43.42  ? 113 LEU A CD1 1 
ATOM   844  C CD2 . LEU A 1 113 ? 132.787 127.464 144.569 1.00 33.51  ? 113 LEU A CD2 1 
ATOM   845  N N   . PHE A 1 114 ? 133.290 123.509 148.165 1.00 38.47  ? 114 PHE A N   1 
ATOM   846  C CA  . PHE A 1 114 ? 133.459 123.012 149.524 1.00 40.89  ? 114 PHE A CA  1 
ATOM   847  C C   . PHE A 1 114 ? 134.925 123.020 149.931 1.00 49.78  ? 114 PHE A C   1 
ATOM   848  O O   . PHE A 1 114 ? 135.264 123.409 151.053 1.00 52.41  ? 114 PHE A O   1 
ATOM   849  C CB  . PHE A 1 114 ? 132.877 121.605 149.633 1.00 40.83  ? 114 PHE A CB  1 
ATOM   850  C CG  . PHE A 1 114 ? 133.148 120.935 150.939 1.00 44.46  ? 114 PHE A CG  1 
ATOM   851  C CD1 . PHE A 1 114 ? 132.564 121.393 152.101 1.00 51.11  ? 114 PHE A CD1 1 
ATOM   852  C CD2 . PHE A 1 114 ? 133.983 119.838 151.003 1.00 46.72  ? 114 PHE A CD2 1 
ATOM   853  C CE1 . PHE A 1 114 ? 132.811 120.773 153.302 1.00 52.38  ? 114 PHE A CE1 1 
ATOM   854  C CE2 . PHE A 1 114 ? 134.233 119.215 152.200 1.00 54.04  ? 114 PHE A CE2 1 
ATOM   855  C CZ  . PHE A 1 114 ? 133.647 119.683 153.352 1.00 55.33  ? 114 PHE A CZ  1 
ATOM   856  N N   . LEU A 1 115 ? 135.810 122.597 149.028 1.00 56.47  ? 115 LEU A N   1 
ATOM   857  C CA  . LEU A 1 115 ? 137.241 122.654 149.307 1.00 47.21  ? 115 LEU A CA  1 
ATOM   858  C C   . LEU A 1 115 ? 137.730 124.088 149.444 1.00 48.47  ? 115 LEU A C   1 
ATOM   859  O O   . LEU A 1 115 ? 138.651 124.353 150.221 1.00 54.83  ? 115 LEU A O   1 
ATOM   860  C CB  . LEU A 1 115 ? 138.023 121.940 148.211 1.00 43.80  ? 115 LEU A CB  1 
ATOM   861  C CG  . LEU A 1 115 ? 137.861 120.427 148.178 1.00 50.99  ? 115 LEU A CG  1 
ATOM   862  C CD1 . LEU A 1 115 ? 138.662 119.852 147.040 1.00 50.24  ? 115 LEU A CD1 1 
ATOM   863  C CD2 . LEU A 1 115 ? 138.295 119.833 149.497 1.00 52.54  ? 115 LEU A CD2 1 
ATOM   864  N N   . VAL A 1 116 ? 137.150 125.017 148.683 1.00 35.99  ? 116 VAL A N   1 
ATOM   865  C CA  . VAL A 1 116 ? 137.490 126.427 148.855 1.00 38.35  ? 116 VAL A CA  1 
ATOM   866  C C   . VAL A 1 116 ? 137.140 126.884 150.262 1.00 46.91  ? 116 VAL A C   1 
ATOM   867  O O   . VAL A 1 116 ? 137.905 127.612 150.906 1.00 45.31  ? 116 VAL A O   1 
ATOM   868  C CB  . VAL A 1 116 ? 136.783 127.287 147.794 1.00 41.27  ? 116 VAL A CB  1 
ATOM   869  C CG1 . VAL A 1 116 ? 136.813 128.739 148.193 1.00 39.17  ? 116 VAL A CG1 1 
ATOM   870  C CG2 . VAL A 1 116 ? 137.444 127.120 146.461 1.00 45.89  ? 116 VAL A CG2 1 
ATOM   871  N N   . PHE A 1 117 ? 135.976 126.467 150.760 1.00 55.33  ? 117 PHE A N   1 
ATOM   872  C CA  . PHE A 1 117 ? 135.555 126.865 152.099 1.00 41.15  ? 117 PHE A CA  1 
ATOM   873  C C   . PHE A 1 117 ? 136.490 126.309 153.165 1.00 43.56  ? 117 PHE A C   1 
ATOM   874  O O   . PHE A 1 117 ? 136.884 127.024 154.092 1.00 56.61  ? 117 PHE A O   1 
ATOM   875  C CB  . PHE A 1 117 ? 134.124 126.403 152.353 1.00 40.36  ? 117 PHE A CB  1 
ATOM   876  C CG  . PHE A 1 117 ? 133.523 126.966 153.599 1.00 48.11  ? 117 PHE A CG  1 
ATOM   877  C CD1 . PHE A 1 117 ? 133.107 128.280 153.648 1.00 53.30  ? 117 PHE A CD1 1 
ATOM   878  C CD2 . PHE A 1 117 ? 133.374 126.182 154.722 1.00 54.13  ? 117 PHE A CD2 1 
ATOM   879  C CE1 . PHE A 1 117 ? 132.555 128.800 154.792 1.00 54.95  ? 117 PHE A CE1 1 
ATOM   880  C CE2 . PHE A 1 117 ? 132.822 126.699 155.869 1.00 56.59  ? 117 PHE A CE2 1 
ATOM   881  C CZ  . PHE A 1 117 ? 132.413 128.008 155.904 1.00 56.35  ? 117 PHE A CZ  1 
ATOM   882  N N   . LEU A 1 118 ? 136.865 125.034 153.046 1.00 53.05  ? 118 LEU A N   1 
ATOM   883  C CA  . LEU A 1 118 ? 137.669 124.390 154.081 1.00 47.92  ? 118 LEU A CA  1 
ATOM   884  C C   . LEU A 1 118 ? 139.023 125.051 154.273 1.00 57.69  ? 118 LEU A C   1 
ATOM   885  O O   . LEU A 1 118 ? 139.618 124.912 155.345 1.00 56.96  ? 118 LEU A O   1 
ATOM   886  C CB  . LEU A 1 118 ? 137.883 122.916 153.752 1.00 45.19  ? 118 LEU A CB  1 
ATOM   887  C CG  . LEU A 1 118 ? 136.741 121.958 154.055 1.00 48.56  ? 118 LEU A CG  1 
ATOM   888  C CD1 . LEU A 1 118 ? 137.252 120.533 154.030 1.00 54.71  ? 118 LEU A CD1 1 
ATOM   889  C CD2 . LEU A 1 118 ? 136.124 122.286 155.395 1.00 53.80  ? 118 LEU A CD2 1 
ATOM   890  N N   . LEU A 1 119 ? 139.528 125.756 153.265 1.00 57.92  ? 119 LEU A N   1 
ATOM   891  C CA  . LEU A 1 119 ? 140.841 126.375 153.372 1.00 52.02  ? 119 LEU A CA  1 
ATOM   892  C C   . LEU A 1 119 ? 140.854 127.558 154.325 1.00 52.66  ? 119 LEU A C   1 
ATOM   893  O O   . LEU A 1 119 ? 141.934 128.068 154.637 1.00 53.21  ? 119 LEU A O   1 
ATOM   894  C CB  . LEU A 1 119 ? 141.323 126.807 151.991 1.00 38.25  ? 119 LEU A CB  1 
ATOM   895  C CG  . LEU A 1 119 ? 142.055 125.703 151.237 1.00 39.88  ? 119 LEU A CG  1 
ATOM   896  C CD1 . LEU A 1 119 ? 142.433 126.156 149.854 1.00 50.05  ? 119 LEU A CD1 1 
ATOM   897  C CD2 . LEU A 1 119 ? 143.284 125.307 152.010 1.00 51.49  ? 119 LEU A CD2 1 
ATOM   898  N N   . PHE A 1 120 ? 139.692 128.005 154.790 1.00 53.06  ? 120 PHE A N   1 
ATOM   899  C CA  . PHE A 1 120 ? 139.610 129.112 155.729 1.00 51.25  ? 120 PHE A CA  1 
ATOM   900  C C   . PHE A 1 120 ? 139.289 128.681 157.150 1.00 57.42  ? 120 PHE A C   1 
ATOM   901  O O   . PHE A 1 120 ? 139.700 129.360 158.089 1.00 71.10  ? 120 PHE A O   1 
ATOM   902  C CB  . PHE A 1 120 ? 138.563 130.126 155.258 1.00 50.46  ? 120 PHE A CB  1 
ATOM   903  C CG  . PHE A 1 120 ? 138.982 130.895 154.043 1.00 46.42  ? 120 PHE A CG  1 
ATOM   904  C CD1 . PHE A 1 120 ? 138.869 130.340 152.786 1.00 49.42  ? 120 PHE A CD1 1 
ATOM   905  C CD2 . PHE A 1 120 ? 139.504 132.166 154.159 1.00 54.78  ? 120 PHE A CD2 1 
ATOM   906  C CE1 . PHE A 1 120 ? 139.260 131.038 151.674 1.00 52.09  ? 120 PHE A CE1 1 
ATOM   907  C CE2 . PHE A 1 120 ? 139.895 132.868 153.045 1.00 59.23  ? 120 PHE A CE2 1 
ATOM   908  C CZ  . PHE A 1 120 ? 139.771 132.303 151.803 1.00 55.50  ? 120 PHE A CZ  1 
ATOM   909  N N   . LEU A 1 121 ? 138.575 127.576 157.333 1.00 44.92  ? 121 LEU A N   1 
ATOM   910  C CA  . LEU A 1 121 ? 138.356 127.051 158.670 1.00 46.20  ? 121 LEU A CA  1 
ATOM   911  C C   . LEU A 1 121 ? 139.657 126.506 159.244 1.00 57.81  ? 121 LEU A C   1 
ATOM   912  O O   . LEU A 1 121 ? 140.509 125.987 158.522 1.00 61.53  ? 121 LEU A O   1 
ATOM   913  C CB  . LEU A 1 121 ? 137.303 125.947 158.649 1.00 44.70  ? 121 LEU A CB  1 
ATOM   914  C CG  . LEU A 1 121 ? 136.009 126.182 157.877 1.00 47.07  ? 121 LEU A CG  1 
ATOM   915  C CD1 . LEU A 1 121 ? 135.040 125.062 158.158 1.00 57.37  ? 121 LEU A CD1 1 
ATOM   916  C CD2 . LEU A 1 121 ? 135.393 127.504 158.249 1.00 53.55  ? 121 LEU A CD2 1 
ATOM   917  N N   . ASN A 1 122 ? 139.811 126.633 160.557 1.00 64.25  ? 122 ASN A N   1 
ATOM   918  C CA  . ASN A 1 122 ? 140.945 126.036 161.241 1.00 60.67  ? 122 ASN A CA  1 
ATOM   919  C C   . ASN A 1 122 ? 140.665 124.566 161.538 1.00 67.94  ? 122 ASN A C   1 
ATOM   920  O O   . ASN A 1 122 ? 139.560 124.064 161.333 1.00 72.35  ? 122 ASN A O   1 
ATOM   921  C CB  . ASN A 1 122 ? 141.272 126.807 162.520 1.00 61.03  ? 122 ASN A CB  1 
ATOM   922  C CG  . ASN A 1 122 ? 140.069 126.990 163.414 1.00 67.10  ? 122 ASN A CG  1 
ATOM   923  O OD1 . ASN A 1 122 ? 138.932 126.931 162.958 1.00 64.98  ? 122 ASN A OD1 1 
ATOM   924  N ND2 . ASN A 1 122 ? 140.315 127.226 164.696 1.00 66.92  ? 122 ASN A ND2 1 
ATOM   925  N N   . PHE A 1 123 ? 141.693 123.871 162.029 1.00 68.90  ? 123 PHE A N   1 
ATOM   926  C CA  . PHE A 1 123 ? 141.604 122.420 162.171 1.00 73.68  ? 123 PHE A CA  1 
ATOM   927  C C   . PHE A 1 123 ? 140.480 122.016 163.114 1.00 73.66  ? 123 PHE A C   1 
ATOM   928  O O   . PHE A 1 123 ? 139.800 121.009 162.883 1.00 78.29  ? 123 PHE A O   1 
ATOM   929  C CB  . PHE A 1 123 ? 142.937 121.857 162.657 1.00 74.16  ? 123 PHE A CB  1 
ATOM   930  C CG  . PHE A 1 123 ? 143.044 120.368 162.532 1.00 76.91  ? 123 PHE A CG  1 
ATOM   931  C CD1 . PHE A 1 123 ? 142.419 119.701 161.497 1.00 74.29  ? 123 PHE A CD1 1 
ATOM   932  C CD2 . PHE A 1 123 ? 143.773 119.634 163.449 1.00 73.50  ? 123 PHE A CD2 1 
ATOM   933  C CE1 . PHE A 1 123 ? 142.517 118.333 161.380 1.00 70.70  ? 123 PHE A CE1 1 
ATOM   934  C CE2 . PHE A 1 123 ? 143.873 118.265 163.336 1.00 72.39  ? 123 PHE A CE2 1 
ATOM   935  C CZ  . PHE A 1 123 ? 143.245 117.614 162.301 1.00 72.12  ? 123 PHE A CZ  1 
ATOM   936  N N   . GLU A 1 124 ? 140.271 122.784 164.184 1.00 73.15  ? 124 GLU A N   1 
ATOM   937  C CA  . GLU A 1 124 ? 139.198 122.467 165.120 1.00 71.86  ? 124 GLU A CA  1 
ATOM   938  C C   . GLU A 1 124 ? 137.837 122.552 164.444 1.00 71.33  ? 124 GLU A C   1 
ATOM   939  O O   . GLU A 1 124 ? 136.970 121.701 164.669 1.00 76.61  ? 124 GLU A O   1 
ATOM   940  C CB  . GLU A 1 124 ? 139.252 123.399 166.332 1.00 71.38  ? 124 GLU A CB  1 
ATOM   941  C CG  . GLU A 1 124 ? 140.415 123.161 167.295 1.00 78.58  ? 124 GLU A CG  1 
ATOM   942  C CD  . GLU A 1 124 ? 141.781 123.258 166.638 1.00 81.94  ? 124 GLU A CD  1 
ATOM   943  O OE1 . GLU A 1 124 ? 142.033 124.255 165.929 1.00 80.79  ? 124 GLU A OE1 1 
ATOM   944  O OE2 . GLU A 1 124 ? 142.601 122.336 166.829 1.00 80.70  ? 124 GLU A OE2 1 
ATOM   945  N N   . GLN A 1 125 ? 137.631 123.568 163.606 1.00 66.62  ? 125 GLN A N   1 
ATOM   946  C CA  . GLN A 1 125 ? 136.345 123.719 162.933 1.00 65.60  ? 125 GLN A CA  1 
ATOM   947  C C   . GLN A 1 125 ? 136.119 122.618 161.908 1.00 65.54  ? 125 GLN A C   1 
ATOM   948  O O   . GLN A 1 125 ? 134.999 122.118 161.767 1.00 72.26  ? 125 GLN A O   1 
ATOM   949  C CB  . GLN A 1 125 ? 136.257 125.091 162.273 1.00 69.28  ? 125 GLN A CB  1 
ATOM   950  C CG  . GLN A 1 125 ? 135.862 126.201 163.215 1.00 70.30  ? 125 GLN A CG  1 
ATOM   951  C CD  . GLN A 1 125 ? 135.835 127.545 162.532 1.00 74.30  ? 125 GLN A CD  1 
ATOM   952  O OE1 . GLN A 1 125 ? 134.775 128.134 162.341 1.00 76.40  ? 125 GLN A OE1 1 
ATOM   953  N NE2 . GLN A 1 125 ? 137.006 128.042 162.162 1.00 70.29  ? 125 GLN A NE2 1 
ATOM   954  N N   . VAL A 1 126 ? 137.166 122.233 161.175 1.00 61.15  ? 126 VAL A N   1 
ATOM   955  C CA  . VAL A 1 126 ? 137.034 121.137 160.219 1.00 61.86  ? 126 VAL A CA  1 
ATOM   956  C C   . VAL A 1 126 ? 136.713 119.837 160.943 1.00 66.39  ? 126 VAL A C   1 
ATOM   957  O O   . VAL A 1 126 ? 135.863 119.055 160.500 1.00 69.74  ? 126 VAL A O   1 
ATOM   958  C CB  . VAL A 1 126 ? 138.306 121.015 159.364 1.00 55.89  ? 126 VAL A CB  1 
ATOM   959  C CG1 . VAL A 1 126 ? 138.294 119.723 158.589 1.00 64.88  ? 126 VAL A CG1 1 
ATOM   960  C CG2 . VAL A 1 126 ? 138.407 122.180 158.416 1.00 56.27  ? 126 VAL A CG2 1 
ATOM   961  N N   . LYS A 1 127 ? 137.383 119.587 162.069 1.00 70.37  ? 127 LYS A N   1 
ATOM   962  C CA  . LYS A 1 127 ? 137.081 118.394 162.852 1.00 68.90  ? 127 LYS A CA  1 
ATOM   963  C C   . LYS A 1 127 ? 135.650 118.423 163.372 1.00 70.95  ? 127 LYS A C   1 
ATOM   964  O O   . LYS A 1 127 ? 134.962 117.397 163.367 1.00 83.23  ? 127 LYS A O   1 
ATOM   965  C CB  . LYS A 1 127 ? 138.070 118.260 164.006 1.00 71.42  ? 127 LYS A CB  1 
ATOM   966  C CG  . LYS A 1 127 ? 139.442 117.775 163.585 1.00 76.02  ? 127 LYS A CG  1 
ATOM   967  C CD  . LYS A 1 127 ? 139.363 116.393 162.966 1.00 80.02  ? 127 LYS A CD  1 
ATOM   968  C CE  . LYS A 1 127 ? 140.434 115.469 163.518 1.00 78.45  ? 127 LYS A CE  1 
ATOM   969  N NZ  . LYS A 1 127 ? 139.995 114.047 163.493 1.00 77.67  ? 127 LYS A NZ  1 
ATOM   970  N N   . SER A 1 128 ? 135.185 119.587 163.831 1.00 67.06  ? 128 SER A N   1 
ATOM   971  C CA  . SER A 1 128 ? 133.810 119.697 164.308 1.00 69.19  ? 128 SER A CA  1 
ATOM   972  C C   . SER A 1 128 ? 132.816 119.433 163.187 1.00 72.87  ? 128 SER A C   1 
ATOM   973  O O   . SER A 1 128 ? 131.803 118.755 163.390 1.00 76.38  ? 128 SER A O   1 
ATOM   974  C CB  . SER A 1 128 ? 133.573 121.079 164.914 1.00 71.58  ? 128 SER A CB  1 
ATOM   975  O OG  . SER A 1 128 ? 134.440 121.310 166.010 1.00 81.51  ? 128 SER A OG  1 
ATOM   976  N N   . LEU A 1 129 ? 133.091 119.960 161.994 1.00 79.17  ? 129 LEU A N   1 
ATOM   977  C CA  . LEU A 1 129 ? 132.226 119.706 160.847 1.00 73.97  ? 129 LEU A CA  1 
ATOM   978  C C   . LEU A 1 129 ? 132.194 118.224 160.506 1.00 73.84  ? 129 LEU A C   1 
ATOM   979  O O   . LEU A 1 129 ? 131.128 117.666 160.218 1.00 80.36  ? 129 LEU A O   1 
ATOM   980  C CB  . LEU A 1 129 ? 132.710 120.524 159.651 1.00 73.09  ? 129 LEU A CB  1 
ATOM   981  C CG  . LEU A 1 129 ? 131.796 120.762 158.453 1.00 75.22  ? 129 LEU A CG  1 
ATOM   982  C CD1 . LEU A 1 129 ? 132.250 122.008 157.724 1.00 74.26  ? 129 LEU A CD1 1 
ATOM   983  C CD2 . LEU A 1 129 ? 131.805 119.578 157.510 1.00 78.40  ? 129 LEU A CD2 1 
ATOM   984  N N   . MET A 1 130 ? 133.355 117.570 160.528 1.00 77.08  ? 130 MET A N   1 
ATOM   985  C CA  . MET A 1 130 ? 133.402 116.148 160.210 1.00 75.47  ? 130 MET A CA  1 
ATOM   986  C C   . MET A 1 130 ? 132.651 115.325 161.246 1.00 73.19  ? 130 MET A C   1 
ATOM   987  O O   . MET A 1 130 ? 131.933 114.384 160.894 1.00 80.58  ? 130 MET A O   1 
ATOM   988  C CB  . MET A 1 130 ? 134.850 115.683 160.097 1.00 76.47  ? 130 MET A CB  1 
ATOM   989  C CG  . MET A 1 130 ? 135.008 114.408 159.301 1.00 83.14  ? 130 MET A CG  1 
ATOM   990  S SD  . MET A 1 130 ? 136.684 113.751 159.295 1.00 105.88 ? 130 MET A SD  1 
ATOM   991  C CE  . MET A 1 130 ? 137.548 114.995 160.242 1.00 81.79  ? 130 MET A CE  1 
ATOM   992  N N   . TYR A 1 131 ? 132.801 115.663 162.529 1.00 72.50  ? 131 TYR A N   1 
ATOM   993  C CA  . TYR A 1 131 ? 132.029 114.979 163.561 1.00 75.13  ? 131 TYR A CA  1 
ATOM   994  C C   . TYR A 1 131 ? 130.539 115.222 163.385 1.00 78.35  ? 131 TYR A C   1 
ATOM   995  O O   . TYR A 1 131 ? 129.726 114.338 163.674 1.00 79.31  ? 131 TYR A O   1 
ATOM   996  C CB  . TYR A 1 131 ? 132.471 115.429 164.952 1.00 76.27  ? 131 TYR A CB  1 
ATOM   997  C CG  . TYR A 1 131 ? 133.931 115.198 165.248 1.00 78.16  ? 131 TYR A CG  1 
ATOM   998  C CD1 . TYR A 1 131 ? 134.623 114.151 164.661 1.00 79.56  ? 131 TYR A CD1 1 
ATOM   999  C CD2 . TYR A 1 131 ? 134.616 116.026 166.123 1.00 80.22  ? 131 TYR A CD2 1 
ATOM   1000 C CE1 . TYR A 1 131 ? 135.959 113.940 164.931 1.00 84.50  ? 131 TYR A CE1 1 
ATOM   1001 C CE2 . TYR A 1 131 ? 135.951 115.824 166.399 1.00 82.61  ? 131 TYR A CE2 1 
ATOM   1002 C CZ  . TYR A 1 131 ? 136.617 114.780 165.802 1.00 85.51  ? 131 TYR A CZ  1 
ATOM   1003 O OH  . TYR A 1 131 ? 137.948 114.576 166.078 1.00 84.82  ? 131 TYR A OH  1 
ATOM   1004 N N   . TRP A 1 132 ? 130.161 116.415 162.927 1.00 83.02  ? 132 TRP A N   1 
ATOM   1005 C CA  . TRP A 1 132 ? 128.758 116.681 162.635 1.00 81.80  ? 132 TRP A CA  1 
ATOM   1006 C C   . TRP A 1 132 ? 128.261 115.814 161.488 1.00 81.87  ? 132 TRP A C   1 
ATOM   1007 O O   . TRP A 1 132 ? 127.110 115.366 161.499 1.00 89.09  ? 132 TRP A O   1 
ATOM   1008 C CB  . TRP A 1 132 ? 128.560 118.160 162.316 1.00 79.49  ? 132 TRP A CB  1 
ATOM   1009 C CG  . TRP A 1 132 ? 127.130 118.534 162.161 1.00 78.32  ? 132 TRP A CG  1 
ATOM   1010 C CD1 . TRP A 1 132 ? 126.253 118.843 163.154 1.00 80.28  ? 132 TRP A CD1 1 
ATOM   1011 C CD2 . TRP A 1 132 ? 126.402 118.635 160.935 1.00 78.98  ? 132 TRP A CD2 1 
ATOM   1012 N NE1 . TRP A 1 132 ? 125.022 119.132 162.623 1.00 86.10  ? 132 TRP A NE1 1 
ATOM   1013 C CE2 . TRP A 1 132 ? 125.088 119.011 161.261 1.00 82.44  ? 132 TRP A CE2 1 
ATOM   1014 C CE3 . TRP A 1 132 ? 126.735 118.445 159.592 1.00 78.95  ? 132 TRP A CE3 1 
ATOM   1015 C CZ2 . TRP A 1 132 ? 124.107 119.199 160.296 1.00 81.20  ? 132 TRP A CZ2 1 
ATOM   1016 C CZ3 . TRP A 1 132 ? 125.761 118.635 158.637 1.00 81.97  ? 132 TRP A CZ3 1 
ATOM   1017 C CH2 . TRP A 1 132 ? 124.464 119.007 158.993 1.00 79.03  ? 132 TRP A CH2 1 
ATOM   1018 N N   . LEU A 1 133 ? 129.108 115.572 160.486 1.00 86.63  ? 133 LEU A N   1 
ATOM   1019 C CA  . LEU A 1 133 ? 128.705 114.716 159.374 1.00 83.35  ? 133 LEU A CA  1 
ATOM   1020 C C   . LEU A 1 133 ? 128.409 113.299 159.846 1.00 88.90  ? 133 LEU A C   1 
ATOM   1021 O O   . LEU A 1 133 ? 127.449 112.674 159.385 1.00 99.58  ? 133 LEU A O   1 
ATOM   1022 C CB  . LEU A 1 133 ? 129.781 114.710 158.291 1.00 83.46  ? 133 LEU A CB  1 
ATOM   1023 C CG  . LEU A 1 133 ? 129.669 115.841 157.271 1.00 87.02  ? 133 LEU A CG  1 
ATOM   1024 C CD1 . LEU A 1 133 ? 130.881 115.871 156.358 1.00 87.21  ? 133 LEU A CD1 1 
ATOM   1025 C CD2 . LEU A 1 133 ? 128.394 115.690 156.467 1.00 88.47  ? 133 LEU A CD2 1 
ATOM   1026 N N   . ASP A 1 134 ? 129.220 112.773 160.758 1.00 86.98  ? 134 ASP A N   1 
ATOM   1027 C CA  . ASP A 1 134 ? 128.935 111.467 161.335 1.00 88.66  ? 134 ASP A CA  1 
ATOM   1028 C C   . ASP A 1 134 ? 129.559 111.455 162.725 1.00 87.80  ? 134 ASP A C   1 
ATOM   1029 O O   . ASP A 1 134 ? 130.788 111.460 162.852 1.00 94.90  ? 134 ASP A O   1 
ATOM   1030 C CB  . ASP A 1 134 ? 129.478 110.355 160.425 1.00 91.41  ? 134 ASP A CB  1 
ATOM   1031 C CG  . ASP A 1 134 ? 129.564 108.982 161.101 1.00 96.81  ? 134 ASP A CG  1 
ATOM   1032 O OD1 . ASP A 1 134 ? 129.529 108.855 162.340 1.00 92.29  ? 134 ASP A OD1 1 
ATOM   1033 O OD2 . ASP A 1 134 ? 129.660 107.988 160.352 1.00 100.84 ? 134 ASP A OD2 1 
ATOM   1034 N N   . PRO A 1 135 ? 128.749 111.434 163.786 1.00 88.81  ? 135 PRO A N   1 
ATOM   1035 C CA  . PRO A 1 135 ? 129.310 111.531 165.144 1.00 90.34  ? 135 PRO A CA  1 
ATOM   1036 C C   . PRO A 1 135 ? 130.210 110.372 165.534 1.00 95.46  ? 135 PRO A C   1 
ATOM   1037 O O   . PRO A 1 135 ? 131.023 110.529 166.452 1.00 94.56  ? 135 PRO A O   1 
ATOM   1038 C CB  . PRO A 1 135 ? 128.061 111.588 166.035 1.00 91.59  ? 135 PRO A CB  1 
ATOM   1039 C CG  . PRO A 1 135 ? 126.949 111.992 165.122 1.00 94.48  ? 135 PRO A CG  1 
ATOM   1040 C CD  . PRO A 1 135 ? 127.280 111.392 163.798 1.00 93.71  ? 135 PRO A CD  1 
ATOM   1041 N N   . ASN A 1 136 ? 130.099 109.216 164.877 1.00 104.59 ? 136 ASN A N   1 
ATOM   1042 C CA  . ASN A 1 136 ? 130.927 108.074 165.246 1.00 103.73 ? 136 ASN A CA  1 
ATOM   1043 C C   . ASN A 1 136 ? 132.402 108.288 164.937 1.00 103.51 ? 136 ASN A C   1 
ATOM   1044 O O   . ASN A 1 136 ? 133.230 107.490 165.385 1.00 104.47 ? 136 ASN A O   1 
ATOM   1045 C CB  . ASN A 1 136 ? 130.431 106.809 164.543 1.00 100.92 ? 136 ASN A CB  1 
ATOM   1046 C CG  . ASN A 1 136 ? 129.056 106.383 165.017 1.00 103.93 ? 136 ASN A CG  1 
ATOM   1047 O OD1 . ASN A 1 136 ? 128.330 107.163 165.634 1.00 104.19 ? 136 ASN A OD1 1 
ATOM   1048 N ND2 . ASN A 1 136 ? 128.691 105.139 164.733 1.00 101.47 ? 136 ASN A ND2 1 
ATOM   1049 N N   . LEU A 1 137 ? 132.748 109.332 164.182 1.00 95.40  ? 137 LEU A N   1 
ATOM   1050 C CA  . LEU A 1 137 ? 134.153 109.617 163.917 1.00 92.58  ? 137 LEU A CA  1 
ATOM   1051 C C   . LEU A 1 137 ? 134.858 110.168 165.146 1.00 94.45  ? 137 LEU A C   1 
ATOM   1052 O O   . LEU A 1 137 ? 136.076 110.012 165.279 1.00 95.72  ? 137 LEU A O   1 
ATOM   1053 C CB  . LEU A 1 137 ? 134.284 110.601 162.759 1.00 86.69  ? 137 LEU A CB  1 
ATOM   1054 C CG  . LEU A 1 137 ? 133.985 110.030 161.379 1.00 86.07  ? 137 LEU A CG  1 
ATOM   1055 C CD1 . LEU A 1 137 ? 134.297 111.052 160.315 1.00 88.95  ? 137 LEU A CD1 1 
ATOM   1056 C CD2 . LEU A 1 137 ? 134.798 108.773 161.163 1.00 92.99  ? 137 LEU A CD2 1 
ATOM   1057 N N   . ARG A 1 138 ? 134.116 110.813 166.048 1.00 91.48  ? 138 ARG A N   1 
ATOM   1058 C CA  . ARG A 1 138 ? 134.738 111.430 167.214 1.00 91.28  ? 138 ARG A CA  1 
ATOM   1059 C C   . ARG A 1 138 ? 135.437 110.392 168.081 1.00 94.80  ? 138 ARG A C   1 
ATOM   1060 O O   . ARG A 1 138 ? 136.548 110.627 168.570 1.00 95.59  ? 138 ARG A O   1 
ATOM   1061 C CB  . ARG A 1 138 ? 133.689 112.192 168.022 1.00 92.56  ? 138 ARG A CB  1 
ATOM   1062 C CG  . ARG A 1 138 ? 134.222 112.831 169.290 1.00 95.00  ? 138 ARG A CG  1 
ATOM   1063 C CD  . ARG A 1 138 ? 133.515 114.140 169.589 1.00 94.39  ? 138 ARG A CD  1 
ATOM   1064 N NE  . ARG A 1 138 ? 132.130 113.935 169.996 1.00 97.07  ? 138 ARG A NE  1 
ATOM   1065 C CZ  . ARG A 1 138 ? 131.084 114.084 169.196 1.00 93.86  ? 138 ARG A CZ  1 
ATOM   1066 N NH1 . ARG A 1 138 ? 131.227 114.435 167.930 1.00 93.76  ? 138 ARG A NH1 1 
ATOM   1067 N NH2 . ARG A 1 138 ? 129.863 113.880 169.680 1.00 92.94  ? 138 ARG A NH2 1 
ATOM   1068 N N   . TYR A 1 139 ? 134.802 109.237 168.280 1.00 106.35 ? 139 TYR A N   1 
ATOM   1069 C CA  . TYR A 1 139 ? 135.425 108.175 169.062 1.00 107.39 ? 139 TYR A CA  1 
ATOM   1070 C C   . TYR A 1 139 ? 136.691 107.663 168.386 1.00 109.36 ? 139 TYR A C   1 
ATOM   1071 O O   . TYR A 1 139 ? 137.684 107.359 169.058 1.00 107.44 ? 139 TYR A O   1 
ATOM   1072 C CB  . TYR A 1 139 ? 134.431 107.035 169.279 1.00 108.93 ? 139 TYR A CB  1 
ATOM   1073 C CG  . TYR A 1 139 ? 133.070 107.494 169.751 1.00 113.20 ? 139 TYR A CG  1 
ATOM   1074 C CD1 . TYR A 1 139 ? 132.943 108.510 170.691 1.00 111.69 ? 139 TYR A CD1 1 
ATOM   1075 C CD2 . TYR A 1 139 ? 131.910 106.914 169.251 1.00 109.31 ? 139 TYR A CD2 1 
ATOM   1076 C CE1 . TYR A 1 139 ? 131.698 108.934 171.122 1.00 110.96 ? 139 TYR A CE1 1 
ATOM   1077 C CE2 . TYR A 1 139 ? 130.662 107.330 169.677 1.00 110.73 ? 139 TYR A CE2 1 
ATOM   1078 C CZ  . TYR A 1 139 ? 130.562 108.340 170.612 1.00 113.54 ? 139 TYR A CZ  1 
ATOM   1079 O OH  . TYR A 1 139 ? 129.322 108.758 171.037 1.00 110.43 ? 139 TYR A OH  1 
ATOM   1080 N N   . ALA A 1 140 ? 136.672 107.555 167.060 1.00 110.66 ? 140 ALA A N   1 
ATOM   1081 C CA  . ALA A 1 140 ? 137.831 107.093 166.303 1.00 109.56 ? 140 ALA A CA  1 
ATOM   1082 C C   . ALA A 1 140 ? 139.024 108.026 166.487 1.00 110.72 ? 140 ALA A C   1 
ATOM   1083 O O   . ALA A 1 140 ? 139.051 109.131 165.946 1.00 111.27 ? 140 ALA A O   1 
ATOM   1084 C CB  . ALA A 1 140 ? 137.483 106.969 164.828 1.00 102.39 ? 140 ALA A CB  1 
ATOM   1085 N N   . GLU A 1 159 ? 147.184 81.258  151.970 1.00 150.53 ? 159 GLU A N   1 
ATOM   1086 C CA  . GLU A 1 159 ? 147.470 81.635  153.349 1.00 152.21 ? 159 GLU A CA  1 
ATOM   1087 C C   . GLU A 1 159 ? 147.273 83.130  153.565 1.00 152.17 ? 159 GLU A C   1 
ATOM   1088 O O   . GLU A 1 159 ? 146.151 83.635  153.509 1.00 151.88 ? 159 GLU A O   1 
ATOM   1089 C CB  . GLU A 1 159 ? 148.899 81.241  153.731 1.00 150.05 ? 159 GLU A CB  1 
ATOM   1090 C CG  . GLU A 1 159 ? 149.126 79.745  153.859 1.00 150.05 ? 159 GLU A CG  1 
ATOM   1091 C CD  . GLU A 1 159 ? 149.428 79.083  152.530 1.00 150.80 ? 159 GLU A CD  1 
ATOM   1092 O OE1 . GLU A 1 159 ? 149.540 79.803  151.517 1.00 152.17 ? 159 GLU A OE1 1 
ATOM   1093 O OE2 . GLU A 1 159 ? 149.556 77.841  152.500 1.00 149.21 ? 159 GLU A OE2 1 
ATOM   1094 N N   . ARG A 1 160 ? 148.381 83.831  153.817 1.00 149.10 ? 160 ARG A N   1 
ATOM   1095 C CA  . ARG A 1 160 ? 148.318 85.270  154.044 1.00 148.18 ? 160 ARG A CA  1 
ATOM   1096 C C   . ARG A 1 160 ? 147.917 86.020  152.781 1.00 150.17 ? 160 ARG A C   1 
ATOM   1097 O O   . ARG A 1 160 ? 147.383 87.131  152.864 1.00 148.42 ? 160 ARG A O   1 
ATOM   1098 C CB  . ARG A 1 160 ? 149.666 85.765  154.568 1.00 147.34 ? 160 ARG A CB  1 
ATOM   1099 C CG  . ARG A 1 160 ? 149.632 87.132  155.221 1.00 148.92 ? 160 ARG A CG  1 
ATOM   1100 C CD  . ARG A 1 160 ? 151.014 87.513  155.732 1.00 148.44 ? 160 ARG A CD  1 
ATOM   1101 N NE  . ARG A 1 160 ? 151.161 88.952  155.916 1.00 149.13 ? 160 ARG A NE  1 
ATOM   1102 C CZ  . ARG A 1 160 ? 152.250 89.536  156.397 1.00 149.35 ? 160 ARG A CZ  1 
ATOM   1103 N NH1 . ARG A 1 160 ? 153.310 88.832  156.760 1.00 147.85 ? 160 ARG A NH1 1 
ATOM   1104 N NH2 . ARG A 1 160 ? 152.276 90.861  156.516 1.00 149.16 ? 160 ARG A NH2 1 
ATOM   1105 N N   . ILE A 1 161 ? 148.167 85.432  151.608 1.00 154.79 ? 161 ILE A N   1 
ATOM   1106 C CA  . ILE A 1 161 ? 147.734 86.043  150.355 1.00 152.72 ? 161 ILE A CA  1 
ATOM   1107 C C   . ILE A 1 161 ? 146.215 86.112  150.290 1.00 151.60 ? 161 ILE A C   1 
ATOM   1108 O O   . ILE A 1 161 ? 145.639 87.135  149.904 1.00 150.55 ? 161 ILE A O   1 
ATOM   1109 C CB  . ILE A 1 161 ? 148.310 85.266  149.157 1.00 152.46 ? 161 ILE A CB  1 
ATOM   1110 C CG1 . ILE A 1 161 ? 149.770 84.890  149.415 1.00 152.66 ? 161 ILE A CG1 1 
ATOM   1111 C CG2 . ILE A 1 161 ? 148.175 86.077  147.880 1.00 150.75 ? 161 ILE A CG2 1 
ATOM   1112 C CD1 . ILE A 1 161 ? 150.374 84.002  148.348 1.00 152.56 ? 161 ILE A CD1 1 
ATOM   1113 N N   . ILE A 1 162 ? 145.544 85.021  150.667 1.00 154.15 ? 162 ILE A N   1 
ATOM   1114 C CA  . ILE A 1 162 ? 144.093 84.947  150.526 1.00 154.57 ? 162 ILE A CA  1 
ATOM   1115 C C   . ILE A 1 162 ? 143.408 85.947  151.447 1.00 153.70 ? 162 ILE A C   1 
ATOM   1116 O O   . ILE A 1 162 ? 142.402 86.565  151.079 1.00 152.36 ? 162 ILE A O   1 
ATOM   1117 C CB  . ILE A 1 162 ? 143.607 83.510  150.786 1.00 153.33 ? 162 ILE A CB  1 
ATOM   1118 C CG1 . ILE A 1 162 ? 144.499 82.508  150.052 1.00 152.14 ? 162 ILE A CG1 1 
ATOM   1119 C CG2 . ILE A 1 162 ? 142.159 83.351  150.350 1.00 151.71 ? 162 ILE A CG2 1 
ATOM   1120 C CD1 . ILE A 1 162 ? 144.082 81.066  150.238 1.00 152.52 ? 162 ILE A CD1 1 
ATOM   1121 N N   . SER A 1 163 ? 143.938 86.120  152.659 1.00 154.12 ? 163 SER A N   1 
ATOM   1122 C CA  . SER A 1 163 ? 143.278 86.973  153.642 1.00 155.06 ? 163 SER A CA  1 
ATOM   1123 C C   . SER A 1 163 ? 143.260 88.434  153.213 1.00 154.91 ? 163 SER A C   1 
ATOM   1124 O O   . SER A 1 163 ? 142.360 89.184  153.608 1.00 153.90 ? 163 SER A O   1 
ATOM   1125 C CB  . SER A 1 163 ? 143.963 86.829  155.000 1.00 154.88 ? 163 SER A CB  1 
ATOM   1126 O OG  . SER A 1 163 ? 145.285 87.336  154.955 1.00 155.63 ? 163 SER A OG  1 
ATOM   1127 N N   . HIS A 1 164 ? 144.237 88.860  152.411 1.00 151.78 ? 164 HIS A N   1 
ATOM   1128 C CA  . HIS A 1 164 ? 144.350 90.270  152.065 1.00 152.05 ? 164 HIS A CA  1 
ATOM   1129 C C   . HIS A 1 164 ? 143.311 90.726  151.051 1.00 151.13 ? 164 HIS A C   1 
ATOM   1130 O O   . HIS A 1 164 ? 143.032 91.927  150.976 1.00 151.96 ? 164 HIS A O   1 
ATOM   1131 C CB  . HIS A 1 164 ? 145.755 90.571  151.543 1.00 151.46 ? 164 HIS A CB  1 
ATOM   1132 C CG  . HIS A 1 164 ? 146.753 90.835  152.627 1.00 152.16 ? 164 HIS A CG  1 
ATOM   1133 N ND1 . HIS A 1 164 ? 146.919 89.993  153.705 1.00 151.38 ? 164 HIS A ND1 1 
ATOM   1134 C CD2 . HIS A 1 164 ? 147.629 91.852  152.805 1.00 152.11 ? 164 HIS A CD2 1 
ATOM   1135 C CE1 . HIS A 1 164 ? 147.858 90.477  154.498 1.00 150.76 ? 164 HIS A CE1 1 
ATOM   1136 N NE2 . HIS A 1 164 ? 148.305 91.604  153.975 1.00 152.33 ? 164 HIS A NE2 1 
ATOM   1137 N N   . PHE A 1 165 ? 142.737 89.812  150.273 1.00 147.09 ? 165 PHE A N   1 
ATOM   1138 C CA  . PHE A 1 165 ? 141.685 90.191  149.340 1.00 147.14 ? 165 PHE A CA  1 
ATOM   1139 C C   . PHE A 1 165 ? 140.449 90.656  150.097 1.00 145.91 ? 165 PHE A C   1 
ATOM   1140 O O   . PHE A 1 165 ? 140.088 90.092  151.134 1.00 146.42 ? 165 PHE A O   1 
ATOM   1141 C CB  . PHE A 1 165 ? 141.325 89.021  148.426 1.00 146.25 ? 165 PHE A CB  1 
ATOM   1142 C CG  . PHE A 1 165 ? 142.514 88.310  147.853 1.00 148.62 ? 165 PHE A CG  1 
ATOM   1143 C CD1 . PHE A 1 165 ? 143.529 89.018  147.235 1.00 148.65 ? 165 PHE A CD1 1 
ATOM   1144 C CD2 . PHE A 1 165 ? 142.610 86.931  147.919 1.00 147.79 ? 165 PHE A CD2 1 
ATOM   1145 C CE1 . PHE A 1 165 ? 144.622 88.363  146.702 1.00 148.91 ? 165 PHE A CE1 1 
ATOM   1146 C CE2 . PHE A 1 165 ? 143.700 86.271  147.384 1.00 148.11 ? 165 PHE A CE2 1 
ATOM   1147 C CZ  . PHE A 1 165 ? 144.707 86.987  146.778 1.00 148.92 ? 165 PHE A CZ  1 
ATOM   1148 N N   . ASP A 1 166 ? 139.798 91.689  149.576 1.00 128.98 ? 166 ASP A N   1 
ATOM   1149 C CA  . ASP A 1 166 ? 138.633 92.269  150.233 1.00 129.59 ? 166 ASP A CA  1 
ATOM   1150 C C   . ASP A 1 166 ? 137.841 93.063  149.201 1.00 129.13 ? 166 ASP A C   1 
ATOM   1151 O O   . ASP A 1 166 ? 138.168 93.068  148.010 1.00 128.98 ? 166 ASP A O   1 
ATOM   1152 C CB  . ASP A 1 166 ? 139.057 93.134  151.424 1.00 130.30 ? 166 ASP A CB  1 
ATOM   1153 C CG  . ASP A 1 166 ? 140.191 94.079  151.083 1.00 128.70 ? 166 ASP A CG  1 
ATOM   1154 O OD1 . ASP A 1 166 ? 141.030 93.720  150.232 1.00 127.42 ? 166 ASP A OD1 1 
ATOM   1155 O OD2 . ASP A 1 166 ? 140.250 95.176  151.673 1.00 129.44 ? 166 ASP A OD2 1 
ATOM   1156 N N   . ILE A 1 167 ? 136.787 93.735  149.665 1.00 121.19 ? 167 ILE A N   1 
ATOM   1157 C CA  . ILE A 1 167 ? 135.975 94.556  148.774 1.00 122.42 ? 167 ILE A CA  1 
ATOM   1158 C C   . ILE A 1 167 ? 136.785 95.737  148.251 1.00 123.05 ? 167 ILE A C   1 
ATOM   1159 O O   . ILE A 1 167 ? 136.621 96.162  147.102 1.00 122.99 ? 167 ILE A O   1 
ATOM   1160 C CB  . ILE A 1 167 ? 134.693 95.011  149.495 1.00 121.92 ? 167 ILE A CB  1 
ATOM   1161 C CG1 . ILE A 1 167 ? 133.917 96.014  148.644 1.00 121.11 ? 167 ILE A CG1 1 
ATOM   1162 C CG2 . ILE A 1 167 ? 135.025 95.605  150.849 1.00 122.46 ? 167 ILE A CG2 1 
ATOM   1163 C CD1 . ILE A 1 167 ? 133.062 95.373  147.580 1.00 120.11 ? 167 ILE A CD1 1 
ATOM   1164 N N   . PHE A 1 168 ? 137.676 96.282  149.080 1.00 119.96 ? 168 PHE A N   1 
ATOM   1165 C CA  . PHE A 1 168 ? 138.472 97.426  148.652 1.00 119.41 ? 168 PHE A CA  1 
ATOM   1166 C C   . PHE A 1 168 ? 139.543 97.026  147.645 1.00 119.87 ? 168 PHE A C   1 
ATOM   1167 O O   . PHE A 1 168 ? 139.921 97.837  146.797 1.00 117.73 ? 168 PHE A O   1 
ATOM   1168 C CB  . PHE A 1 168 ? 139.083 98.113  149.869 1.00 116.91 ? 168 PHE A CB  1 
ATOM   1169 C CG  . PHE A 1 168 ? 138.117 98.272  151.001 1.00 119.31 ? 168 PHE A CG  1 
ATOM   1170 C CD1 . PHE A 1 168 ? 136.967 99.027  150.839 1.00 119.10 ? 168 PHE A CD1 1 
ATOM   1171 C CD2 . PHE A 1 168 ? 138.339 97.649  152.216 1.00 120.34 ? 168 PHE A CD2 1 
ATOM   1172 C CE1 . PHE A 1 168 ? 136.065 99.170  151.871 1.00 118.58 ? 168 PHE A CE1 1 
ATOM   1173 C CE2 . PHE A 1 168 ? 137.441 97.787  153.254 1.00 120.66 ? 168 PHE A CE2 1 
ATOM   1174 C CZ  . PHE A 1 168 ? 136.302 98.549  153.081 1.00 119.42 ? 168 PHE A CZ  1 
ATOM   1175 N N   . ALA A 1 169 ? 140.035 95.787  147.706 1.00 117.78 ? 169 ALA A N   1 
ATOM   1176 C CA  . ALA A 1 169 ? 140.892 95.298  146.631 1.00 115.40 ? 169 ALA A CA  1 
ATOM   1177 C C   . ALA A 1 169 ? 140.119 95.217  145.321 1.00 113.80 ? 169 ALA A C   1 
ATOM   1178 O O   . ALA A 1 169 ? 140.645 95.559  144.256 1.00 113.22 ? 169 ALA A O   1 
ATOM   1179 C CB  . ALA A 1 169 ? 141.476 93.935  146.998 1.00 116.36 ? 169 ALA A CB  1 
ATOM   1180 N N   . PHE A 1 170 ? 138.864 94.771  145.389 1.00 115.40 ? 170 PHE A N   1 
ATOM   1181 C CA  . PHE A 1 170 ? 137.988 94.776  144.222 1.00 114.03 ? 170 PHE A CA  1 
ATOM   1182 C C   . PHE A 1 170 ? 137.827 96.186  143.672 1.00 114.36 ? 170 PHE A C   1 
ATOM   1183 O O   . PHE A 1 170 ? 137.907 96.411  142.457 1.00 114.69 ? 170 PHE A O   1 
ATOM   1184 C CB  . PHE A 1 170 ? 136.631 94.191  144.614 1.00 113.85 ? 170 PHE A CB  1 
ATOM   1185 C CG  . PHE A 1 170 ? 135.806 93.713  143.460 1.00 115.80 ? 170 PHE A CG  1 
ATOM   1186 C CD1 . PHE A 1 170 ? 136.195 92.613  142.719 1.00 115.74 ? 170 PHE A CD1 1 
ATOM   1187 C CD2 . PHE A 1 170 ? 134.621 94.352  143.134 1.00 115.79 ? 170 PHE A CD2 1 
ATOM   1188 C CE1 . PHE A 1 170 ? 135.424 92.167  141.663 1.00 116.46 ? 170 PHE A CE1 1 
ATOM   1189 C CE2 . PHE A 1 170 ? 133.847 93.913  142.080 1.00 115.04 ? 170 PHE A CE2 1 
ATOM   1190 C CZ  . PHE A 1 170 ? 134.247 92.818  141.345 1.00 115.52 ? 170 PHE A CZ  1 
ATOM   1191 N N   . GLY A 1 171 ? 137.603 97.154  144.561 1.00 110.97 ? 171 GLY A N   1 
ATOM   1192 C CA  . GLY A 1 171 ? 137.453 98.530  144.122 1.00 110.13 ? 171 GLY A CA  1 
ATOM   1193 C C   . GLY A 1 171 ? 138.716 99.087  143.496 1.00 114.12 ? 171 GLY A C   1 
ATOM   1194 O O   . GLY A 1 171 ? 138.661 99.770  142.474 1.00 113.11 ? 171 GLY A O   1 
ATOM   1195 N N   . HIS A 1 172 ? 139.871 98.807  144.104 1.00 109.90 ? 172 HIS A N   1 
ATOM   1196 C CA  . HIS A 1 172 ? 141.139 99.258  143.542 1.00 103.65 ? 172 HIS A CA  1 
ATOM   1197 C C   . HIS A 1 172 ? 141.367 98.657  142.163 1.00 99.87  ? 172 HIS A C   1 
ATOM   1198 O O   . HIS A 1 172 ? 141.776 99.358  141.230 1.00 102.08 ? 172 HIS A O   1 
ATOM   1199 C CB  . HIS A 1 172 ? 142.284 98.887  144.484 1.00 101.58 ? 172 HIS A CB  1 
ATOM   1200 C CG  . HIS A 1 172 ? 143.413 99.869  144.484 1.00 106.30 ? 172 HIS A CG  1 
ATOM   1201 N ND1 . HIS A 1 172 ? 143.966 100.369 143.326 1.00 109.19 ? 172 HIS A ND1 1 
ATOM   1202 C CD2 . HIS A 1 172 ? 144.095 100.442 145.504 1.00 107.81 ? 172 HIS A CD2 1 
ATOM   1203 C CE1 . HIS A 1 172 ? 144.940 101.208 143.632 1.00 105.72 ? 172 HIS A CE1 1 
ATOM   1204 N NE2 . HIS A 1 172 ? 145.039 101.271 144.947 1.00 108.33 ? 172 HIS A NE2 1 
ATOM   1205 N N   . PHE A 1 173 ? 141.088 97.361  142.012 1.00 92.40  ? 173 PHE A N   1 
ATOM   1206 C CA  . PHE A 1 173 ? 141.267 96.711  140.720 1.00 92.69  ? 173 PHE A CA  1 
ATOM   1207 C C   . PHE A 1 173 ? 140.347 97.317  139.669 1.00 95.45  ? 173 PHE A C   1 
ATOM   1208 O O   . PHE A 1 173 ? 140.774 97.577  138.539 1.00 97.95  ? 173 PHE A O   1 
ATOM   1209 C CB  . PHE A 1 173 ? 141.035 95.204  140.863 1.00 94.33  ? 173 PHE A CB  1 
ATOM   1210 C CG  . PHE A 1 173 ? 140.578 94.522  139.603 1.00 92.75  ? 173 PHE A CG  1 
ATOM   1211 C CD1 . PHE A 1 173 ? 141.488 93.860  138.804 1.00 92.85  ? 173 PHE A CD1 1 
ATOM   1212 C CD2 . PHE A 1 173 ? 139.240 94.484  139.252 1.00 94.44  ? 173 PHE A CD2 1 
ATOM   1213 C CE1 . PHE A 1 173 ? 141.085 93.220  137.656 1.00 92.13  ? 173 PHE A CE1 1 
ATOM   1214 C CE2 . PHE A 1 173 ? 138.833 93.847  138.104 1.00 96.25  ? 173 PHE A CE2 1 
ATOM   1215 C CZ  . PHE A 1 173 ? 139.757 93.210  137.307 1.00 95.39  ? 173 PHE A CZ  1 
ATOM   1216 N N   . TRP A 1 174 ? 139.080 97.555  140.016 1.00 94.80  ? 174 TRP A N   1 
ATOM   1217 C CA  . TRP A 1 174 ? 138.161 98.097  139.021 1.00 91.92  ? 174 TRP A CA  1 
ATOM   1218 C C   . TRP A 1 174 ? 138.469 99.552  138.697 1.00 94.41  ? 174 TRP A C   1 
ATOM   1219 O O   . TRP A 1 174 ? 138.301 99.977  137.549 1.00 97.76  ? 174 TRP A O   1 
ATOM   1220 C CB  . TRP A 1 174 ? 136.717 97.936  139.485 1.00 91.73  ? 174 TRP A CB  1 
ATOM   1221 C CG  . TRP A 1 174 ? 136.136 96.641  139.037 1.00 95.05  ? 174 TRP A CG  1 
ATOM   1222 C CD1 . TRP A 1 174 ? 135.858 95.554  139.809 1.00 97.56  ? 174 TRP A CD1 1 
ATOM   1223 C CD2 . TRP A 1 174 ? 135.785 96.283  137.698 1.00 96.17  ? 174 TRP A CD2 1 
ATOM   1224 N NE1 . TRP A 1 174 ? 135.343 94.544  139.034 1.00 93.07  ? 174 TRP A NE1 1 
ATOM   1225 C CE2 . TRP A 1 174 ? 135.288 94.968  137.733 1.00 96.38  ? 174 TRP A CE2 1 
ATOM   1226 C CE3 . TRP A 1 174 ? 135.836 96.951  136.472 1.00 98.61  ? 174 TRP A CE3 1 
ATOM   1227 C CZ2 . TRP A 1 174 ? 134.847 94.307  136.593 1.00 98.13  ? 174 TRP A CZ2 1 
ATOM   1228 C CZ3 . TRP A 1 174 ? 135.397 96.294  135.340 1.00 96.77  ? 174 TRP A CZ3 1 
ATOM   1229 C CH2 . TRP A 1 174 ? 134.909 94.986  135.407 1.00 97.07  ? 174 TRP A CH2 1 
ATOM   1230 N N   . GLY A 1 175 ? 138.933 100.324 139.678 1.00 86.19  ? 175 GLY A N   1 
ATOM   1231 C CA  . GLY A 1 175 ? 139.400 101.664 139.380 1.00 84.52  ? 175 GLY A CA  1 
ATOM   1232 C C   . GLY A 1 175 ? 140.587 101.655 138.441 1.00 86.23  ? 175 GLY A C   1 
ATOM   1233 O O   . GLY A 1 175 ? 140.662 102.461 137.512 1.00 87.26  ? 175 GLY A O   1 
ATOM   1234 N N   . TRP A 1 176 ? 141.523 100.728 138.657 1.00 85.04  ? 176 TRP A N   1 
ATOM   1235 C CA  . TRP A 1 176 ? 142.658 100.607 137.749 1.00 80.86  ? 176 TRP A CA  1 
ATOM   1236 C C   . TRP A 1 176 ? 142.206 100.189 136.359 1.00 80.99  ? 176 TRP A C   1 
ATOM   1237 O O   . TRP A 1 176 ? 142.763 100.644 135.355 1.00 82.33  ? 176 TRP A O   1 
ATOM   1238 C CB  . TRP A 1 176 ? 143.678 99.617  138.304 1.00 76.58  ? 176 TRP A CB  1 
ATOM   1239 C CG  . TRP A 1 176 ? 144.808 100.277 139.017 1.00 78.90  ? 176 TRP A CG  1 
ATOM   1240 C CD1 . TRP A 1 176 ? 145.223 100.034 140.289 1.00 81.63  ? 176 TRP A CD1 1 
ATOM   1241 C CD2 . TRP A 1 176 ? 145.668 101.300 138.504 1.00 79.31  ? 176 TRP A CD2 1 
ATOM   1242 N NE1 . TRP A 1 176 ? 146.289 100.838 140.601 1.00 82.54  ? 176 TRP A NE1 1 
ATOM   1243 C CE2 . TRP A 1 176 ? 146.581 101.624 139.520 1.00 81.48  ? 176 TRP A CE2 1 
ATOM   1244 C CE3 . TRP A 1 176 ? 145.756 101.969 137.282 1.00 77.18  ? 176 TRP A CE3 1 
ATOM   1245 C CZ2 . TRP A 1 176 ? 147.565 102.587 139.353 1.00 79.65  ? 176 TRP A CZ2 1 
ATOM   1246 C CZ3 . TRP A 1 176 ? 146.730 102.922 137.120 1.00 74.90  ? 176 TRP A CZ3 1 
ATOM   1247 C CH2 . TRP A 1 176 ? 147.624 103.223 138.148 1.00 79.48  ? 176 TRP A CH2 1 
ATOM   1248 N N   . ALA A 1 177 ? 141.200 99.316  136.278 1.00 75.67  ? 177 ALA A N   1 
ATOM   1249 C CA  . ALA A 1 177 ? 140.665 98.927  134.978 1.00 74.31  ? 177 ALA A CA  1 
ATOM   1250 C C   . ALA A 1 177 ? 140.054 100.119 134.255 1.00 76.62  ? 177 ALA A C   1 
ATOM   1251 O O   . ALA A 1 177 ? 140.272 100.306 133.052 1.00 83.06  ? 177 ALA A O   1 
ATOM   1252 C CB  . ALA A 1 177 ? 139.634 97.815  135.145 1.00 74.00  ? 177 ALA A CB  1 
ATOM   1253 N N   . MET A 1 178 ? 139.290 100.942 134.973 1.00 73.83  ? 178 MET A N   1 
ATOM   1254 C CA  . MET A 1 178 ? 138.713 102.133 134.358 1.00 78.66  ? 178 MET A CA  1 
ATOM   1255 C C   . MET A 1 178 ? 139.802 103.103 133.909 1.00 79.56  ? 178 MET A C   1 
ATOM   1256 O O   . MET A 1 178 ? 139.711 103.701 132.827 1.00 74.45  ? 178 MET A O   1 
ATOM   1257 C CB  . MET A 1 178 ? 137.749 102.807 135.335 1.00 75.53  ? 178 MET A CB  1 
ATOM   1258 C CG  . MET A 1 178 ? 136.853 103.860 134.709 1.00 76.27  ? 178 MET A CG  1 
ATOM   1259 S SD  . MET A 1 178 ? 137.508 105.531 134.872 1.00 89.79  ? 178 MET A SD  1 
ATOM   1260 C CE  . MET A 1 178 ? 137.979 105.544 136.598 1.00 76.88  ? 178 MET A CE  1 
ATOM   1261 N N   . LYS A 1 179 ? 140.842 103.273 134.728 1.00 77.43  ? 179 LYS A N   1 
ATOM   1262 C CA  . LYS A 1 179 ? 141.949 104.140 134.338 1.00 72.60  ? 179 LYS A CA  1 
ATOM   1263 C C   . LYS A 1 179 ? 142.629 103.616 133.083 1.00 75.86  ? 179 LYS A C   1 
ATOM   1264 O O   . LYS A 1 179 ? 142.959 104.386 132.179 1.00 82.76  ? 179 LYS A O   1 
ATOM   1265 C CB  . LYS A 1 179 ? 142.958 104.266 135.478 1.00 76.23  ? 179 LYS A CB  1 
ATOM   1266 C CG  . LYS A 1 179 ? 142.400 104.852 136.756 1.00 76.27  ? 179 LYS A CG  1 
ATOM   1267 C CD  . LYS A 1 179 ? 143.237 104.430 137.952 1.00 74.66  ? 179 LYS A CD  1 
ATOM   1268 C CE  . LYS A 1 179 ? 142.680 104.984 139.248 1.00 76.75  ? 179 LYS A CE  1 
ATOM   1269 N NZ  . LYS A 1 179 ? 143.431 104.476 140.429 1.00 78.08  ? 179 LYS A NZ  1 
ATOM   1270 N N   . ALA A 1 180 ? 142.849 102.303 133.010 1.00 76.29  ? 180 ALA A N   1 
ATOM   1271 C CA  . ALA A 1 180 ? 143.447 101.719 131.815 1.00 77.11  ? 180 ALA A CA  1 
ATOM   1272 C C   . ALA A 1 180 ? 142.564 101.946 130.598 1.00 77.30  ? 180 ALA A C   1 
ATOM   1273 O O   . ALA A 1 180 ? 143.063 102.192 129.495 1.00 73.34  ? 180 ALA A O   1 
ATOM   1274 C CB  . ALA A 1 180 ? 143.693 100.227 132.027 1.00 76.57  ? 180 ALA A CB  1 
ATOM   1275 N N   . LEU A 1 181 ? 141.246 101.864 130.784 1.00 74.83  ? 181 LEU A N   1 
ATOM   1276 C CA  . LEU A 1 181 ? 140.320 102.155 129.695 1.00 72.84  ? 181 LEU A CA  1 
ATOM   1277 C C   . LEU A 1 181 ? 140.491 103.582 129.198 1.00 75.49  ? 181 LEU A C   1 
ATOM   1278 O O   . LEU A 1 181 ? 140.545 103.830 127.988 1.00 75.41  ? 181 LEU A O   1 
ATOM   1279 C CB  . LEU A 1 181 ? 138.883 101.930 130.160 1.00 69.29  ? 181 LEU A CB  1 
ATOM   1280 C CG  . LEU A 1 181 ? 137.928 101.309 129.148 1.00 71.72  ? 181 LEU A CG  1 
ATOM   1281 C CD1 . LEU A 1 181 ? 138.377 99.911  128.826 1.00 76.07  ? 181 LEU A CD1 1 
ATOM   1282 C CD2 . LEU A 1 181 ? 136.508 101.312 129.679 1.00 72.14  ? 181 LEU A CD2 1 
ATOM   1283 N N   . LEU A 1 182 ? 140.579 104.537 130.121 1.00 71.62  ? 182 LEU A N   1 
ATOM   1284 C CA  . LEU A 1 182 ? 140.584 105.940 129.725 1.00 69.57  ? 182 LEU A CA  1 
ATOM   1285 C C   . LEU A 1 182 ? 141.944 106.434 129.239 1.00 74.83  ? 182 LEU A C   1 
ATOM   1286 O O   . LEU A 1 182 ? 141.991 107.354 128.417 1.00 75.69  ? 182 LEU A O   1 
ATOM   1287 C CB  . LEU A 1 182 ? 140.106 106.819 130.880 1.00 67.60  ? 182 LEU A CB  1 
ATOM   1288 C CG  . LEU A 1 182 ? 138.599 107.072 130.939 1.00 70.43  ? 182 LEU A CG  1 
ATOM   1289 C CD1 . LEU A 1 182 ? 138.137 107.729 129.655 1.00 67.37  ? 182 LEU A CD1 1 
ATOM   1290 C CD2 . LEU A 1 182 ? 137.828 105.800 131.200 1.00 73.25  ? 182 LEU A CD2 1 
ATOM   1291 N N   . ILE A 1 183 ? 143.041 105.854 129.717 1.00 73.01  ? 183 ILE A N   1 
ATOM   1292 C CA  . ILE A 1 183 ? 144.380 106.319 129.378 1.00 65.33  ? 183 ILE A CA  1 
ATOM   1293 C C   . ILE A 1 183 ? 144.930 105.598 128.157 1.00 63.45  ? 183 ILE A C   1 
ATOM   1294 O O   . ILE A 1 183 ? 145.492 106.230 127.263 1.00 64.66  ? 183 ILE A O   1 
ATOM   1295 C CB  . ILE A 1 183 ? 145.328 106.149 130.584 1.00 64.09  ? 183 ILE A CB  1 
ATOM   1296 C CG1 . ILE A 1 183 ? 144.741 106.803 131.830 1.00 60.66  ? 183 ILE A CG1 1 
ATOM   1297 C CG2 . ILE A 1 183 ? 146.677 106.744 130.281 1.00 68.04  ? 183 ILE A CG2 1 
ATOM   1298 C CD1 . ILE A 1 183 ? 144.369 108.218 131.640 1.00 63.78  ? 183 ILE A CD1 1 
ATOM   1299 N N   . ARG A 1 184 ? 144.778 104.275 128.118 1.00 67.87  ? 184 ARG A N   1 
ATOM   1300 C CA  . ARG A 1 184 ? 145.227 103.437 127.009 1.00 74.87  ? 184 ARG A CA  1 
ATOM   1301 C C   . ARG A 1 184 ? 146.717 103.687 126.741 1.00 78.94  ? 184 ARG A C   1 
ATOM   1302 O O   . ARG A 1 184 ? 147.127 104.229 125.714 1.00 81.87  ? 184 ARG A O   1 
ATOM   1303 C CB  . ARG A 1 184 ? 144.338 103.671 125.774 1.00 77.46  ? 184 ARG A CB  1 
ATOM   1304 C CG  . ARG A 1 184 ? 144.826 103.173 124.408 1.00 75.62  ? 184 ARG A CG  1 
ATOM   1305 C CD  . ARG A 1 184 ? 145.473 101.797 124.488 1.00 77.00  ? 184 ARG A CD  1 
ATOM   1306 N NE  . ARG A 1 184 ? 145.313 101.047 123.250 1.00 84.60  ? 184 ARG A NE  1 
ATOM   1307 C CZ  . ARG A 1 184 ? 145.599 99.761  123.107 1.00 84.78  ? 184 ARG A CZ  1 
ATOM   1308 N NH1 . ARG A 1 184 ? 146.050 99.036  124.117 1.00 77.65  ? 184 ARG A NH1 1 
ATOM   1309 N NH2 . ARG A 1 184 ? 145.434 99.191  121.919 1.00 81.16  ? 184 ARG A NH2 1 
ATOM   1310 N N   . SER A 1 185 ? 147.524 103.334 127.739 1.00 72.85  ? 185 SER A N   1 
ATOM   1311 C CA  . SER A 1 185 ? 148.969 103.243 127.582 1.00 69.27  ? 185 SER A CA  1 
ATOM   1312 C C   . SER A 1 185 ? 149.556 102.424 128.722 1.00 68.99  ? 185 SER A C   1 
ATOM   1313 O O   . SER A 1 185 ? 149.409 102.791 129.890 1.00 73.68  ? 185 SER A O   1 
ATOM   1314 C CB  . SER A 1 185 ? 149.603 104.632 127.543 1.00 71.90  ? 185 SER A CB  1 
ATOM   1315 O OG  . SER A 1 185 ? 150.946 104.562 127.100 1.00 76.97  ? 185 SER A OG  1 
ATOM   1316 N N   . TYR A 1 186 ? 150.213 101.309 128.401 1.00 72.19  ? 186 TYR A N   1 
ATOM   1317 C CA  . TYR A 1 186 ? 150.863 100.523 129.444 1.00 72.68  ? 186 TYR A CA  1 
ATOM   1318 C C   . TYR A 1 186 ? 151.971 101.319 130.116 1.00 72.76  ? 186 TYR A C   1 
ATOM   1319 O O   . TYR A 1 186 ? 152.111 101.288 131.342 1.00 75.37  ? 186 TYR A O   1 
ATOM   1320 C CB  . TYR A 1 186 ? 151.423 99.228  128.863 1.00 73.92  ? 186 TYR A CB  1 
ATOM   1321 C CG  . TYR A 1 186 ? 150.402 98.154  128.566 1.00 73.85  ? 186 TYR A CG  1 
ATOM   1322 C CD1 . TYR A 1 186 ? 149.990 97.271  129.551 1.00 75.77  ? 186 TYR A CD1 1 
ATOM   1323 C CD2 . TYR A 1 186 ? 149.871 98.009  127.296 1.00 71.24  ? 186 TYR A CD2 1 
ATOM   1324 C CE1 . TYR A 1 186 ? 149.071 96.280  129.281 1.00 74.73  ? 186 TYR A CE1 1 
ATOM   1325 C CE2 . TYR A 1 186 ? 148.951 97.022  127.018 1.00 73.46  ? 186 TYR A CE2 1 
ATOM   1326 C CZ  . TYR A 1 186 ? 148.557 96.160  128.012 1.00 72.70  ? 186 TYR A CZ  1 
ATOM   1327 O OH  . TYR A 1 186 ? 147.640 95.176  127.734 1.00 70.14  ? 186 TYR A OH  1 
ATOM   1328 N N   . GLY A 1 187 ? 152.752 102.053 129.334 1.00 74.43  ? 187 GLY A N   1 
ATOM   1329 C CA  . GLY A 1 187 ? 153.849 102.840 129.847 1.00 73.40  ? 187 GLY A CA  1 
ATOM   1330 C C   . GLY A 1 187 ? 153.445 104.047 130.653 1.00 75.37  ? 187 GLY A C   1 
ATOM   1331 O O   . GLY A 1 187 ? 154.313 104.773 131.142 1.00 81.67  ? 187 GLY A O   1 
ATOM   1332 N N   . LEU A 1 188 ? 152.145 104.304 130.783 1.00 71.45  ? 188 LEU A N   1 
ATOM   1333 C CA  . LEU A 1 188 ? 151.618 105.317 131.684 1.00 69.38  ? 188 LEU A CA  1 
ATOM   1334 C C   . LEU A 1 188 ? 150.994 104.703 132.925 1.00 65.66  ? 188 LEU A C   1 
ATOM   1335 O O   . LEU A 1 188 ? 151.353 105.068 134.049 1.00 73.75  ? 188 LEU A O   1 
ATOM   1336 C CB  . LEU A 1 188 ? 150.574 106.182 130.968 1.00 64.19  ? 188 LEU A CB  1 
ATOM   1337 C CG  . LEU A 1 188 ? 151.043 107.126 129.867 1.00 66.98  ? 188 LEU A CG  1 
ATOM   1338 C CD1 . LEU A 1 188 ? 150.036 108.239 129.693 1.00 69.02  ? 188 LEU A CD1 1 
ATOM   1339 C CD2 . LEU A 1 188 ? 152.414 107.683 130.184 1.00 70.40  ? 188 LEU A CD2 1 
ATOM   1340 N N   . CYS A 1 189 ? 150.060 103.771 132.740 1.00 65.52  ? 189 CYS A N   1 
ATOM   1341 C CA  . CYS A 1 189 ? 149.401 103.147 133.878 1.00 66.24  ? 189 CYS A CA  1 
ATOM   1342 C C   . CYS A 1 189 ? 150.395 102.382 134.738 1.00 71.90  ? 189 CYS A C   1 
ATOM   1343 O O   . CYS A 1 189 ? 150.345 102.462 135.968 1.00 83.29  ? 189 CYS A O   1 
ATOM   1344 C CB  . CYS A 1 189 ? 148.283 102.227 133.395 1.00 73.39  ? 189 CYS A CB  1 
ATOM   1345 S SG  . CYS A 1 189 ? 146.893 103.081 132.626 1.00 80.79  ? 189 CYS A SG  1 
ATOM   1346 N N   . TRP A 1 190 ? 151.314 101.643 134.115 1.00 72.56  ? 190 TRP A N   1 
ATOM   1347 C CA  . TRP A 1 190 ? 152.293 100.891 134.893 1.00 71.91  ? 190 TRP A CA  1 
ATOM   1348 C C   . TRP A 1 190 ? 153.269 101.817 135.606 1.00 72.17  ? 190 TRP A C   1 
ATOM   1349 O O   . TRP A 1 190 ? 153.654 101.553 136.751 1.00 77.25  ? 190 TRP A O   1 
ATOM   1350 C CB  . TRP A 1 190 ? 153.036 99.911  133.992 1.00 69.92  ? 190 TRP A CB  1 
ATOM   1351 C CG  . TRP A 1 190 ? 152.431 98.553  134.000 1.00 69.44  ? 190 TRP A CG  1 
ATOM   1352 C CD1 . TRP A 1 190 ? 151.600 98.024  133.064 1.00 73.88  ? 190 TRP A CD1 1 
ATOM   1353 C CD2 . TRP A 1 190 ? 152.615 97.540  134.991 1.00 70.00  ? 190 TRP A CD2 1 
ATOM   1354 N NE1 . TRP A 1 190 ? 151.248 96.747  133.412 1.00 77.40  ? 190 TRP A NE1 1 
ATOM   1355 C CE2 . TRP A 1 190 ? 151.861 96.426  134.592 1.00 75.22  ? 190 TRP A CE2 1 
ATOM   1356 C CE3 . TRP A 1 190 ? 153.344 97.469  136.179 1.00 73.67  ? 190 TRP A CE3 1 
ATOM   1357 C CZ2 . TRP A 1 190 ? 151.813 95.255  135.337 1.00 74.70  ? 190 TRP A CZ2 1 
ATOM   1358 C CZ3 . TRP A 1 190 ? 153.295 96.307  136.916 1.00 76.08  ? 190 TRP A CZ3 1 
ATOM   1359 C CH2 . TRP A 1 190 ? 152.536 95.216  136.493 1.00 78.05  ? 190 TRP A CH2 1 
ATOM   1360 N N   . THR A 1 191 ? 153.686 102.901 134.950 1.00 66.67  ? 191 THR A N   1 
ATOM   1361 C CA  . THR A 1 191 ? 154.569 103.859 135.606 1.00 70.80  ? 191 THR A CA  1 
ATOM   1362 C C   . THR A 1 191 ? 153.898 104.468 136.826 1.00 76.10  ? 191 THR A C   1 
ATOM   1363 O O   . THR A 1 191 ? 154.493 104.537 137.909 1.00 78.14  ? 191 THR A O   1 
ATOM   1364 C CB  . THR A 1 191 ? 154.981 104.955 134.630 1.00 70.31  ? 191 THR A CB  1 
ATOM   1365 O OG1 . THR A 1 191 ? 155.517 104.359 133.445 1.00 87.45  ? 191 THR A OG1 1 
ATOM   1366 C CG2 . THR A 1 191 ? 156.024 105.853 135.258 1.00 68.06  ? 191 THR A CG2 1 
ATOM   1367 N N   . ILE A 1 192 ? 152.647 104.903 136.673 1.00 70.84  ? 192 ILE A N   1 
ATOM   1368 C CA  . ILE A 1 192 ? 151.920 105.483 137.797 1.00 61.57  ? 192 ILE A CA  1 
ATOM   1369 C C   . ILE A 1 192 ? 151.748 104.452 138.904 1.00 66.76  ? 192 ILE A C   1 
ATOM   1370 O O   . ILE A 1 192 ? 151.925 104.755 140.088 1.00 80.49  ? 192 ILE A O   1 
ATOM   1371 C CB  . ILE A 1 192 ? 150.564 106.037 137.335 1.00 59.10  ? 192 ILE A CB  1 
ATOM   1372 C CG1 . ILE A 1 192 ? 150.751 107.337 136.555 1.00 62.58  ? 192 ILE A CG1 1 
ATOM   1373 C CG2 . ILE A 1 192 ? 149.659 106.244 138.523 1.00 62.28  ? 192 ILE A CG2 1 
ATOM   1374 C CD1 . ILE A 1 192 ? 149.517 107.758 135.775 1.00 66.97  ? 192 ILE A CD1 1 
ATOM   1375 N N   . SER A 1 193 ? 151.407 103.217 138.536 1.00 55.37  ? 193 SER A N   1 
ATOM   1376 C CA  . SER A 1 193 ? 151.194 102.178 139.535 1.00 56.13  ? 193 SER A CA  1 
ATOM   1377 C C   . SER A 1 193 ? 152.459 101.915 140.338 1.00 63.11  ? 193 SER A C   1 
ATOM   1378 O O   . SER A 1 193 ? 152.429 101.900 141.572 1.00 79.70  ? 193 SER A O   1 
ATOM   1379 C CB  . SER A 1 193 ? 150.712 100.898 138.861 1.00 63.60  ? 193 SER A CB  1 
ATOM   1380 O OG  . SER A 1 193 ? 150.633 99.838  139.793 1.00 71.57  ? 193 SER A OG  1 
ATOM   1381 N N   . ILE A 1 194 ? 153.587 101.717 139.655 1.00 54.56  ? 194 ILE A N   1 
ATOM   1382 C CA  . ILE A 1 194 ? 154.830 101.414 140.359 1.00 66.70  ? 194 ILE A CA  1 
ATOM   1383 C C   . ILE A 1 194 ? 155.251 102.592 141.227 1.00 76.13  ? 194 ILE A C   1 
ATOM   1384 O O   . ILE A 1 194 ? 155.621 102.425 142.397 1.00 83.29  ? 194 ILE A O   1 
ATOM   1385 C CB  . ILE A 1 194 ? 155.936 101.025 139.364 1.00 65.32  ? 194 ILE A CB  1 
ATOM   1386 C CG1 . ILE A 1 194 ? 155.588 99.707  138.677 1.00 71.48  ? 194 ILE A CG1 1 
ATOM   1387 C CG2 . ILE A 1 194 ? 157.266 100.912 140.075 1.00 66.42  ? 194 ILE A CG2 1 
ATOM   1388 C CD1 . ILE A 1 194 ? 156.630 99.246  137.690 1.00 72.00  ? 194 ILE A CD1 1 
ATOM   1389 N N   . THR A 1 195 ? 155.191 103.805 140.673 1.00 66.42  ? 195 THR A N   1 
ATOM   1390 C CA  . THR A 1 195 ? 155.605 104.979 141.429 1.00 63.98  ? 195 THR A CA  1 
ATOM   1391 C C   . THR A 1 195 ? 154.746 105.167 142.672 1.00 63.26  ? 195 THR A C   1 
ATOM   1392 O O   . THR A 1 195 ? 155.265 105.395 143.771 1.00 71.45  ? 195 THR A O   1 
ATOM   1393 C CB  . THR A 1 195 ? 155.541 106.214 140.535 1.00 65.42  ? 195 THR A CB  1 
ATOM   1394 O OG1 . THR A 1 195 ? 156.723 106.284 139.730 1.00 72.80  ? 195 THR A OG1 1 
ATOM   1395 C CG2 . THR A 1 195 ? 155.424 107.462 141.368 1.00 71.70  ? 195 THR A CG2 1 
ATOM   1396 N N   . TRP A 1 196 ? 153.425 105.051 142.528 1.00 58.09  ? 196 TRP A N   1 
ATOM   1397 C CA  . TRP A 1 196 ? 152.554 105.280 143.672 1.00 60.22  ? 196 TRP A CA  1 
ATOM   1398 C C   . TRP A 1 196 ? 152.687 104.176 144.709 1.00 66.54  ? 196 TRP A C   1 
ATOM   1399 O O   . TRP A 1 196 ? 152.617 104.443 145.912 1.00 77.68  ? 196 TRP A O   1 
ATOM   1400 C CB  . TRP A 1 196 ? 151.101 105.412 143.233 1.00 63.14  ? 196 TRP A CB  1 
ATOM   1401 C CG  . TRP A 1 196 ? 150.187 105.499 144.401 1.00 63.03  ? 196 TRP A CG  1 
ATOM   1402 C CD1 . TRP A 1 196 ? 149.128 104.691 144.670 1.00 62.80  ? 196 TRP A CD1 1 
ATOM   1403 C CD2 . TRP A 1 196 ? 150.264 106.433 145.483 1.00 69.69  ? 196 TRP A CD2 1 
ATOM   1404 N NE1 . TRP A 1 196 ? 148.531 105.068 145.845 1.00 66.43  ? 196 TRP A NE1 1 
ATOM   1405 C CE2 . TRP A 1 196 ? 149.212 106.137 146.364 1.00 71.61  ? 196 TRP A CE2 1 
ATOM   1406 C CE3 . TRP A 1 196 ? 151.115 107.499 145.786 1.00 72.78  ? 196 TRP A CE3 1 
ATOM   1407 C CZ2 . TRP A 1 196 ? 148.988 106.864 147.527 1.00 72.52  ? 196 TRP A CZ2 1 
ATOM   1408 C CZ3 . TRP A 1 196 ? 150.894 108.215 146.941 1.00 64.78  ? 196 TRP A CZ3 1 
ATOM   1409 C CH2 . TRP A 1 196 ? 149.840 107.896 147.797 1.00 66.78  ? 196 TRP A CH2 1 
ATOM   1410 N N   . GLU A 1 197 ? 152.854 102.927 144.276 1.00 72.21  ? 197 GLU A N   1 
ATOM   1411 C CA  . GLU A 1 197 ? 153.033 101.857 145.249 1.00 76.44  ? 197 GLU A CA  1 
ATOM   1412 C C   . GLU A 1 197 ? 154.323 102.045 146.031 1.00 78.39  ? 197 GLU A C   1 
ATOM   1413 O O   . GLU A 1 197 ? 154.352 101.847 147.252 1.00 83.49  ? 197 GLU A O   1 
ATOM   1414 C CB  . GLU A 1 197 ? 153.007 100.498 144.554 1.00 74.11  ? 197 GLU A CB  1 
ATOM   1415 C CG  . GLU A 1 197 ? 151.639 100.116 144.028 1.00 76.69  ? 197 GLU A CG  1 
ATOM   1416 C CD  . GLU A 1 197 ? 150.521 100.516 144.965 1.00 82.28  ? 197 GLU A CD  1 
ATOM   1417 O OE1 . GLU A 1 197 ? 150.531 100.076 146.132 1.00 86.11  ? 197 GLU A OE1 1 
ATOM   1418 O OE2 . GLU A 1 197 ? 149.630 101.276 144.535 1.00 82.38  ? 197 GLU A OE2 1 
ATOM   1419 N N   . LEU A 1 198 ? 155.399 102.452 145.353 1.00 69.37  ? 198 LEU A N   1 
ATOM   1420 C CA  . LEU A 1 198 ? 156.638 102.722 146.071 1.00 69.90  ? 198 LEU A CA  1 
ATOM   1421 C C   . LEU A 1 198 ? 156.499 103.922 147.002 1.00 73.13  ? 198 LEU A C   1 
ATOM   1422 O O   . LEU A 1 198 ? 157.095 103.932 148.082 1.00 76.25  ? 198 LEU A O   1 
ATOM   1423 C CB  . LEU A 1 198 ? 157.782 102.929 145.084 1.00 70.79  ? 198 LEU A CB  1 
ATOM   1424 C CG  . LEU A 1 198 ? 158.140 101.674 144.292 1.00 69.22  ? 198 LEU A CG  1 
ATOM   1425 C CD1 . LEU A 1 198 ? 159.424 101.872 143.515 1.00 73.58  ? 198 LEU A CD1 1 
ATOM   1426 C CD2 . LEU A 1 198 ? 158.250 100.483 145.220 1.00 69.69  ? 198 LEU A CD2 1 
ATOM   1427 N N   . THR A 1 199 ? 155.706 104.927 146.621 1.00 71.58  ? 199 THR A N   1 
ATOM   1428 C CA  . THR A 1 199 ? 155.490 106.063 147.516 1.00 69.31  ? 199 THR A CA  1 
ATOM   1429 C C   . THR A 1 199 ? 154.675 105.664 148.743 1.00 73.74  ? 199 THR A C   1 
ATOM   1430 O O   . THR A 1 199 ? 154.972 106.099 149.862 1.00 81.21  ? 199 THR A O   1 
ATOM   1431 C CB  . THR A 1 199 ? 154.811 107.206 146.768 1.00 67.99  ? 199 THR A CB  1 
ATOM   1432 O OG1 . THR A 1 199 ? 155.585 107.546 145.613 1.00 74.60  ? 199 THR A OG1 1 
ATOM   1433 C CG2 . THR A 1 199 ? 154.700 108.423 147.656 1.00 70.94  ? 199 THR A CG2 1 
ATOM   1434 N N   . GLU A 1 200 ? 153.644 104.836 148.555 1.00 79.13  ? 200 GLU A N   1 
ATOM   1435 C CA  . GLU A 1 200 ? 152.890 104.317 149.693 1.00 78.14  ? 200 GLU A CA  1 
ATOM   1436 C C   . GLU A 1 200 ? 153.782 103.504 150.614 1.00 79.68  ? 200 GLU A C   1 
ATOM   1437 O O   . GLU A 1 200 ? 153.658 103.585 151.841 1.00 83.80  ? 200 GLU A O   1 
ATOM   1438 C CB  . GLU A 1 200 ? 151.721 103.458 149.218 1.00 77.86  ? 200 GLU A CB  1 
ATOM   1439 C CG  . GLU A 1 200 ? 150.395 104.178 149.137 1.00 77.96  ? 200 GLU A CG  1 
ATOM   1440 C CD  . GLU A 1 200 ? 149.250 103.235 148.836 1.00 84.92  ? 200 GLU A CD  1 
ATOM   1441 O OE1 . GLU A 1 200 ? 149.088 102.242 149.574 1.00 86.42  ? 200 GLU A OE1 1 
ATOM   1442 O OE2 . GLU A 1 200 ? 148.509 103.486 147.865 1.00 89.79  ? 200 GLU A OE2 1 
ATOM   1443 N N   . LEU A 1 201 ? 154.673 102.697 150.042 1.00 80.62  ? 201 LEU A N   1 
ATOM   1444 C CA  . LEU A 1 201 ? 155.607 101.948 150.871 1.00 82.34  ? 201 LEU A CA  1 
ATOM   1445 C C   . LEU A 1 201 ? 156.554 102.881 151.616 1.00 82.58  ? 201 LEU A C   1 
ATOM   1446 O O   . LEU A 1 201 ? 156.876 102.641 152.784 1.00 84.67  ? 201 LEU A O   1 
ATOM   1447 C CB  . LEU A 1 201 ? 156.387 100.955 150.018 1.00 83.76  ? 201 LEU A CB  1 
ATOM   1448 C CG  . LEU A 1 201 ? 157.197 99.945  150.823 1.00 87.19  ? 201 LEU A CG  1 
ATOM   1449 C CD1 . LEU A 1 201 ? 156.272 99.164  151.735 1.00 86.23  ? 201 LEU A CD1 1 
ATOM   1450 C CD2 . LEU A 1 201 ? 157.956 99.016  149.895 1.00 87.31  ? 201 LEU A CD2 1 
ATOM   1451 N N   . PHE A 1 202 ? 157.012 103.948 150.959 1.00 73.74  ? 202 PHE A N   1 
ATOM   1452 C CA  . PHE A 1 202 ? 157.925 104.876 151.617 1.00 77.15  ? 202 PHE A CA  1 
ATOM   1453 C C   . PHE A 1 202 ? 157.240 105.631 152.744 1.00 85.99  ? 202 PHE A C   1 
ATOM   1454 O O   . PHE A 1 202 ? 157.882 105.995 153.734 1.00 91.50  ? 202 PHE A O   1 
ATOM   1455 C CB  . PHE A 1 202 ? 158.499 105.868 150.615 1.00 77.02  ? 202 PHE A CB  1 
ATOM   1456 C CG  . PHE A 1 202 ? 159.356 106.923 151.245 1.00 80.26  ? 202 PHE A CG  1 
ATOM   1457 C CD1 . PHE A 1 202 ? 160.592 106.603 151.774 1.00 79.15  ? 202 PHE A CD1 1 
ATOM   1458 C CD2 . PHE A 1 202 ? 158.915 108.230 151.334 1.00 80.42  ? 202 PHE A CD2 1 
ATOM   1459 C CE1 . PHE A 1 202 ? 161.380 107.570 152.358 1.00 81.10  ? 202 PHE A CE1 1 
ATOM   1460 C CE2 . PHE A 1 202 ? 159.698 109.199 151.920 1.00 80.53  ? 202 PHE A CE2 1 
ATOM   1461 C CZ  . PHE A 1 202 ? 160.932 108.869 152.431 1.00 81.47  ? 202 PHE A CZ  1 
ATOM   1462 N N   . PHE A 1 203 ? 155.937 105.876 152.618 1.00 84.36  ? 203 PHE A N   1 
ATOM   1463 C CA  . PHE A 1 203 ? 155.234 106.664 153.623 1.00 79.69  ? 203 PHE A CA  1 
ATOM   1464 C C   . PHE A 1 203 ? 154.830 105.789 154.802 1.00 77.63  ? 203 PHE A C   1 
ATOM   1465 O O   . PHE A 1 203 ? 153.892 106.115 155.534 1.00 80.28  ? 203 PHE A O   1 
ATOM   1466 C CB  . PHE A 1 203 ? 154.013 107.351 153.014 1.00 73.38  ? 203 PHE A CB  1 
ATOM   1467 C CG  . PHE A 1 203 ? 154.340 108.607 152.262 1.00 73.29  ? 203 PHE A CG  1 
ATOM   1468 C CD1 . PHE A 1 203 ? 155.630 109.095 152.234 1.00 72.65  ? 203 PHE A CD1 1 
ATOM   1469 C CD2 . PHE A 1 203 ? 153.359 109.296 151.577 1.00 76.06  ? 203 PHE A CD2 1 
ATOM   1470 C CE1 . PHE A 1 203 ? 155.933 110.244 151.542 1.00 74.93  ? 203 PHE A CE1 1 
ATOM   1471 C CE2 . PHE A 1 203 ? 153.660 110.446 150.883 1.00 75.16  ? 203 PHE A CE2 1 
ATOM   1472 C CZ  . PHE A 1 203 ? 154.948 110.919 150.866 1.00 75.58  ? 203 PHE A CZ  1 
ATOM   1473 N N   . MET A 1 204 ? 155.529 104.665 154.979 1.00 84.54  ? 204 MET A N   1 
ATOM   1474 C CA  . MET A 1 204 ? 155.295 103.809 156.135 1.00 88.88  ? 204 MET A CA  1 
ATOM   1475 C C   . MET A 1 204 ? 155.660 104.504 157.439 1.00 97.06  ? 204 MET A C   1 
ATOM   1476 O O   . MET A 1 204 ? 155.065 104.208 158.481 1.00 99.11  ? 204 MET A O   1 
ATOM   1477 C CB  . MET A 1 204 ? 156.093 102.514 155.997 1.00 90.67  ? 204 MET A CB  1 
ATOM   1478 C CG  . MET A 1 204 ? 157.598 102.722 155.954 1.00 90.28  ? 204 MET A CG  1 
ATOM   1479 S SD  . MET A 1 204 ? 158.524 101.179 156.031 1.00 95.61  ? 204 MET A SD  1 
ATOM   1480 C CE  . MET A 1 204 ? 159.682 101.551 157.343 1.00 90.25  ? 204 MET A CE  1 
ATOM   1481 N N   . HIS A 1 205 ? 156.633 105.417 157.408 1.00 96.65  ? 205 HIS A N   1 
ATOM   1482 C CA  . HIS A 1 205 ? 157.083 106.055 158.641 1.00 99.63  ? 205 HIS A CA  1 
ATOM   1483 C C   . HIS A 1 205 ? 155.999 106.929 159.261 1.00 97.59  ? 205 HIS A C   1 
ATOM   1484 O O   . HIS A 1 205 ? 156.023 107.180 160.471 1.00 94.34  ? 205 HIS A O   1 
ATOM   1485 C CB  . HIS A 1 205 ? 158.350 106.868 158.378 1.00 93.48  ? 205 HIS A CB  1 
ATOM   1486 C CG  . HIS A 1 205 ? 158.219 107.855 157.262 1.00 92.89  ? 205 HIS A CG  1 
ATOM   1487 N ND1 . HIS A 1 205 ? 157.266 108.849 157.251 1.00 95.85  ? 205 HIS A ND1 1 
ATOM   1488 C CD2 . HIS A 1 205 ? 158.928 108.002 156.118 1.00 96.14  ? 205 HIS A CD2 1 
ATOM   1489 C CE1 . HIS A 1 205 ? 157.391 109.565 156.149 1.00 98.67  ? 205 HIS A CE1 1 
ATOM   1490 N NE2 . HIS A 1 205 ? 158.392 109.071 155.444 1.00 96.46  ? 205 HIS A NE2 1 
ATOM   1491 N N   . LEU A 1 206 ? 155.047 107.406 158.455 1.00 96.75  ? 206 LEU A N   1 
ATOM   1492 C CA  . LEU A 1 206 ? 153.955 108.202 159.002 1.00 95.17  ? 206 LEU A CA  1 
ATOM   1493 C C   . LEU A 1 206 ? 153.085 107.373 159.936 1.00 102.07 ? 206 LEU A C   1 
ATOM   1494 O O   . LEU A 1 206 ? 152.681 107.847 161.003 1.00 103.80 ? 206 LEU A O   1 
ATOM   1495 C CB  . LEU A 1 206 ? 153.113 108.791 157.871 1.00 91.95  ? 206 LEU A CB  1 
ATOM   1496 C CG  . LEU A 1 206 ? 153.799 109.832 156.984 1.00 100.78 ? 206 LEU A CG  1 
ATOM   1497 C CD1 . LEU A 1 206 ? 152.781 110.521 156.101 1.00 103.74 ? 206 LEU A CD1 1 
ATOM   1498 C CD2 . LEU A 1 206 ? 154.560 110.854 157.812 1.00 103.02 ? 206 LEU A CD2 1 
ATOM   1499 N N   . LEU A 1 207 ? 152.797 106.129 159.558 1.00 120.85 ? 207 LEU A N   1 
ATOM   1500 C CA  . LEU A 1 207 ? 151.921 105.248 160.333 1.00 121.71 ? 207 LEU A CA  1 
ATOM   1501 C C   . LEU A 1 207 ? 152.615 103.911 160.549 1.00 120.04 ? 207 LEU A C   1 
ATOM   1502 O O   . LEU A 1 207 ? 152.222 102.885 159.979 1.00 115.62 ? 207 LEU A O   1 
ATOM   1503 C CB  . LEU A 1 207 ? 150.578 105.064 159.624 1.00 118.55 ? 207 LEU A CB  1 
ATOM   1504 C CG  . LEU A 1 207 ? 149.376 104.726 160.504 1.00 119.37 ? 207 LEU A CG  1 
ATOM   1505 C CD1 . LEU A 1 207 ? 148.840 105.981 161.174 1.00 117.02 ? 207 LEU A CD1 1 
ATOM   1506 C CD2 . LEU A 1 207 ? 148.288 104.041 159.691 1.00 118.86 ? 207 LEU A CD2 1 
ATOM   1507 N N   . PRO A 1 208 ? 153.658 103.882 161.382 1.00 128.31 ? 208 PRO A N   1 
ATOM   1508 C CA  . PRO A 1 208 ? 154.372 102.626 161.634 1.00 128.40 ? 208 PRO A CA  1 
ATOM   1509 C C   . PRO A 1 208 ? 153.688 101.713 162.638 1.00 130.48 ? 208 PRO A C   1 
ATOM   1510 O O   . PRO A 1 208 ? 154.157 100.588 162.841 1.00 131.01 ? 208 PRO A O   1 
ATOM   1511 C CB  . PRO A 1 208 ? 155.723 103.112 162.172 1.00 126.31 ? 208 PRO A CB  1 
ATOM   1512 C CG  . PRO A 1 208 ? 155.388 104.377 162.886 1.00 126.25 ? 208 PRO A CG  1 
ATOM   1513 C CD  . PRO A 1 208 ? 154.232 105.006 162.146 1.00 124.87 ? 208 PRO A CD  1 
ATOM   1514 N N   . ASN A 1 209 ? 152.604 102.166 163.274 1.00 139.43 ? 209 ASN A N   1 
ATOM   1515 C CA  . ASN A 1 209 ? 151.932 101.342 164.274 1.00 139.24 ? 209 ASN A CA  1 
ATOM   1516 C C   . ASN A 1 209 ? 151.295 100.108 163.647 1.00 140.44 ? 209 ASN A C   1 
ATOM   1517 O O   . ASN A 1 209 ? 151.336 99.018  164.230 1.00 138.33 ? 209 ASN A O   1 
ATOM   1518 C CB  . ASN A 1 209 ? 150.884 102.171 165.014 1.00 137.60 ? 209 ASN A CB  1 
ATOM   1519 C CG  . ASN A 1 209 ? 150.148 103.128 164.098 1.00 138.64 ? 209 ASN A CG  1 
ATOM   1520 O OD1 . ASN A 1 209 ? 150.747 103.738 163.212 1.00 136.00 ? 209 ASN A OD1 1 
ATOM   1521 N ND2 . ASN A 1 209 ? 148.843 103.265 164.307 1.00 139.67 ? 209 ASN A ND2 1 
ATOM   1522 N N   . PHE A 1 210 ? 150.697 100.258 162.467 1.00 147.52 ? 210 PHE A N   1 
ATOM   1523 C CA  . PHE A 1 210 ? 150.033 99.136  161.818 1.00 147.02 ? 210 PHE A CA  1 
ATOM   1524 C C   . PHE A 1 210 ? 151.049 98.084  161.393 1.00 145.83 ? 210 PHE A C   1 
ATOM   1525 O O   . PHE A 1 210 ? 152.131 98.404  160.893 1.00 144.69 ? 210 PHE A O   1 
ATOM   1526 C CB  . PHE A 1 210 ? 149.233 99.621  160.609 1.00 146.22 ? 210 PHE A CB  1 
ATOM   1527 C CG  . PHE A 1 210 ? 148.696 98.511  159.750 1.00 146.23 ? 210 PHE A CG  1 
ATOM   1528 C CD1 . PHE A 1 210 ? 147.896 97.519  160.294 1.00 146.56 ? 210 PHE A CD1 1 
ATOM   1529 C CD2 . PHE A 1 210 ? 148.983 98.464  158.396 1.00 145.37 ? 210 PHE A CD2 1 
ATOM   1530 C CE1 . PHE A 1 210 ? 147.401 96.497  159.505 1.00 145.98 ? 210 PHE A CE1 1 
ATOM   1531 C CE2 . PHE A 1 210 ? 148.487 97.445  157.603 1.00 146.64 ? 210 PHE A CE2 1 
ATOM   1532 C CZ  . PHE A 1 210 ? 147.697 96.461  158.158 1.00 146.73 ? 210 PHE A CZ  1 
ATOM   1533 N N   . ALA A 1 211 ? 150.693 96.818  161.596 1.00 149.64 ? 211 ALA A N   1 
ATOM   1534 C CA  . ALA A 1 211 ? 151.551 95.696  161.230 1.00 149.41 ? 211 ALA A CA  1 
ATOM   1535 C C   . ALA A 1 211 ? 151.373 95.415  159.743 1.00 149.50 ? 211 ALA A C   1 
ATOM   1536 O O   . ALA A 1 211 ? 150.311 94.954  159.313 1.00 149.13 ? 211 ALA A O   1 
ATOM   1537 C CB  . ALA A 1 211 ? 151.218 94.465  162.069 1.00 148.89 ? 211 ALA A CB  1 
ATOM   1538 N N   . GLU A 1 212 ? 152.413 95.690  158.961 1.00 150.47 ? 212 GLU A N   1 
ATOM   1539 C CA  . GLU A 1 212 ? 152.369 95.470  157.524 1.00 150.46 ? 212 GLU A CA  1 
ATOM   1540 C C   . GLU A 1 212 ? 153.780 95.198  157.030 1.00 150.34 ? 212 GLU A C   1 
ATOM   1541 O O   . GLU A 1 212 ? 154.766 95.521  157.697 1.00 151.22 ? 212 GLU A O   1 
ATOM   1542 C CB  . GLU A 1 212 ? 151.759 96.666  156.785 1.00 148.46 ? 212 GLU A CB  1 
ATOM   1543 C CG  . GLU A 1 212 ? 152.314 98.017  157.211 1.00 147.21 ? 212 GLU A CG  1 
ATOM   1544 C CD  . GLU A 1 212 ? 153.562 98.408  156.445 1.00 148.09 ? 212 GLU A CD  1 
ATOM   1545 O OE1 . GLU A 1 212 ? 153.507 98.457  155.198 1.00 148.41 ? 212 GLU A OE1 1 
ATOM   1546 O OE2 . GLU A 1 212 ? 154.600 98.664  157.091 1.00 146.88 ? 212 GLU A OE2 1 
ATOM   1547 N N   . CYS A 1 213 ? 153.860 94.600  155.848 1.00 139.00 ? 213 CYS A N   1 
ATOM   1548 C CA  . CYS A 1 213 ? 155.126 94.280  155.212 1.00 138.41 ? 213 CYS A CA  1 
ATOM   1549 C C   . CYS A 1 213 ? 155.145 94.848  153.800 1.00 137.56 ? 213 CYS A C   1 
ATOM   1550 O O   . CYS A 1 213 ? 154.110 95.195  153.226 1.00 136.01 ? 213 CYS A O   1 
ATOM   1551 C CB  . CYS A 1 213 ? 155.363 92.765  155.189 1.00 137.43 ? 213 CYS A CB  1 
ATOM   1552 S SG  . CYS A 1 213 ? 157.087 92.284  154.951 1.00 139.89 ? 213 CYS A SG  1 
ATOM   1553 N N   . TRP A 1 214 ? 156.353 94.948  153.244 1.00 132.88 ? 214 TRP A N   1 
ATOM   1554 C CA  . TRP A 1 214 ? 156.499 95.436  151.878 1.00 131.84 ? 214 TRP A CA  1 
ATOM   1555 C C   . TRP A 1 214 ? 155.808 94.518  150.881 1.00 132.74 ? 214 TRP A C   1 
ATOM   1556 O O   . TRP A 1 214 ? 155.343 94.978  149.832 1.00 133.00 ? 214 TRP A O   1 
ATOM   1557 C CB  . TRP A 1 214 ? 157.979 95.574  151.529 1.00 131.17 ? 214 TRP A CB  1 
ATOM   1558 C CG  . TRP A 1 214 ? 158.841 94.572  152.226 1.00 133.24 ? 214 TRP A CG  1 
ATOM   1559 C CD1 . TRP A 1 214 ? 159.512 94.745  153.402 1.00 133.82 ? 214 TRP A CD1 1 
ATOM   1560 C CD2 . TRP A 1 214 ? 159.124 93.235  151.795 1.00 133.94 ? 214 TRP A CD2 1 
ATOM   1561 N NE1 . TRP A 1 214 ? 160.196 93.599  153.729 1.00 134.89 ? 214 TRP A NE1 1 
ATOM   1562 C CE2 . TRP A 1 214 ? 159.975 92.657  152.758 1.00 134.89 ? 214 TRP A CE2 1 
ATOM   1563 C CE3 . TRP A 1 214 ? 158.743 92.472  150.687 1.00 130.73 ? 214 TRP A CE3 1 
ATOM   1564 C CZ2 . TRP A 1 214 ? 160.450 91.352  152.648 1.00 132.05 ? 214 TRP A CZ2 1 
ATOM   1565 C CZ3 . TRP A 1 214 ? 159.215 91.177  150.580 1.00 131.68 ? 214 TRP A CZ3 1 
ATOM   1566 C CH2 . TRP A 1 214 ? 160.060 90.631  151.554 1.00 132.31 ? 214 TRP A CH2 1 
ATOM   1567 N N   . TRP A 1 215 ? 155.725 93.222  151.191 1.00 136.10 ? 215 TRP A N   1 
ATOM   1568 C CA  . TRP A 1 215 ? 155.139 92.277  150.249 1.00 135.06 ? 215 TRP A CA  1 
ATOM   1569 C C   . TRP A 1 215 ? 153.658 92.550  150.030 1.00 135.27 ? 215 TRP A C   1 
ATOM   1570 O O   . TRP A 1 215 ? 153.161 92.367  148.914 1.00 136.28 ? 215 TRP A O   1 
ATOM   1571 C CB  . TRP A 1 215 ? 155.369 90.845  150.735 1.00 134.44 ? 215 TRP A CB  1 
ATOM   1572 C CG  . TRP A 1 215 ? 154.276 90.296  151.590 1.00 138.01 ? 215 TRP A CG  1 
ATOM   1573 C CD1 . TRP A 1 215 ? 154.071 90.544  152.913 1.00 139.27 ? 215 TRP A CD1 1 
ATOM   1574 C CD2 . TRP A 1 215 ? 153.255 89.375  151.190 1.00 139.49 ? 215 TRP A CD2 1 
ATOM   1575 N NE1 . TRP A 1 215 ? 152.971 89.850  153.360 1.00 140.87 ? 215 TRP A NE1 1 
ATOM   1576 C CE2 . TRP A 1 215 ? 152.455 89.122  152.321 1.00 139.24 ? 215 TRP A CE2 1 
ATOM   1577 C CE3 . TRP A 1 215 ? 152.936 88.744  149.984 1.00 137.01 ? 215 TRP A CE3 1 
ATOM   1578 C CZ2 . TRP A 1 215 ? 151.357 88.267  152.283 1.00 136.48 ? 215 TRP A CZ2 1 
ATOM   1579 C CZ3 . TRP A 1 215 ? 151.845 87.894  149.948 1.00 137.17 ? 215 TRP A CZ3 1 
ATOM   1580 C CH2 . TRP A 1 215 ? 151.069 87.664  151.090 1.00 136.63 ? 215 TRP A CH2 1 
ATOM   1581 N N   . ASP A 1 216 ? 152.953 93.022  151.061 1.00 126.33 ? 216 ASP A N   1 
ATOM   1582 C CA  . ASP A 1 216 ? 151.531 93.322  150.921 1.00 126.41 ? 216 ASP A CA  1 
ATOM   1583 C C   . ASP A 1 216 ? 151.310 94.393  149.860 1.00 129.05 ? 216 ASP A C   1 
ATOM   1584 O O   . ASP A 1 216 ? 150.460 94.242  148.975 1.00 128.05 ? 216 ASP A O   1 
ATOM   1585 C CB  . ASP A 1 216 ? 150.968 93.760  152.279 1.00 129.85 ? 216 ASP A CB  1 
ATOM   1586 C CG  . ASP A 1 216 ? 149.759 94.694  152.172 1.00 131.87 ? 216 ASP A CG  1 
ATOM   1587 O OD1 . ASP A 1 216 ? 148.959 94.589  151.218 1.00 129.64 ? 216 ASP A OD1 1 
ATOM   1588 O OD2 . ASP A 1 216 ? 149.611 95.556  153.065 1.00 131.47 ? 216 ASP A OD2 1 
ATOM   1589 N N   . GLN A 1 217 ? 152.080 95.474  149.917 1.00 122.02 ? 217 GLN A N   1 
ATOM   1590 C CA  . GLN A 1 217 ? 151.931 96.571  148.974 1.00 117.37 ? 217 GLN A CA  1 
ATOM   1591 C C   . GLN A 1 217 ? 152.834 96.429  147.759 1.00 115.52 ? 217 GLN A C   1 
ATOM   1592 O O   . GLN A 1 217 ? 152.940 97.371  146.969 1.00 114.60 ? 217 GLN A O   1 
ATOM   1593 C CB  . GLN A 1 217 ? 152.193 97.910  149.669 1.00 117.03 ? 217 GLN A CB  1 
ATOM   1594 C CG  . GLN A 1 217 ? 151.121 98.291  150.676 1.00 118.32 ? 217 GLN A CG  1 
ATOM   1595 C CD  . GLN A 1 217 ? 150.119 99.282  150.116 1.00 118.46 ? 217 GLN A CD  1 
ATOM   1596 O OE1 . GLN A 1 217 ? 150.004 99.449  148.903 1.00 115.65 ? 217 GLN A OE1 1 
ATOM   1597 N NE2 . GLN A 1 217 ? 149.382 99.942  151.002 1.00 119.22 ? 217 GLN A NE2 1 
ATOM   1598 N N   . VAL A 1 218 ? 153.500 95.287  147.598 1.00 118.61 ? 218 VAL A N   1 
ATOM   1599 C CA  . VAL A 1 218 ? 154.225 95.027  146.361 1.00 119.32 ? 218 VAL A CA  1 
ATOM   1600 C C   . VAL A 1 218 ? 153.462 93.993  145.541 1.00 119.59 ? 218 VAL A C   1 
ATOM   1601 O O   . VAL A 1 218 ? 152.929 94.313  144.476 1.00 119.30 ? 218 VAL A O   1 
ATOM   1602 C CB  . VAL A 1 218 ? 155.670 94.573  146.636 1.00 116.96 ? 218 VAL A CB  1 
ATOM   1603 C CG1 . VAL A 1 218 ? 156.238 93.826  145.437 1.00 116.55 ? 218 VAL A CG1 1 
ATOM   1604 C CG2 . VAL A 1 218 ? 156.539 95.777  146.964 1.00 115.16 ? 218 VAL A CG2 1 
ATOM   1605 N N   . ILE A 1 219 ? 153.343 92.767  146.051 1.00 122.80 ? 219 ILE A N   1 
ATOM   1606 C CA  . ILE A 1 219 ? 152.723 91.706  145.263 1.00 122.36 ? 219 ILE A CA  1 
ATOM   1607 C C   . ILE A 1 219 ? 151.240 91.989  145.066 1.00 120.29 ? 219 ILE A C   1 
ATOM   1608 O O   . ILE A 1 219 ? 150.776 92.197  143.938 1.00 118.94 ? 219 ILE A O   1 
ATOM   1609 C CB  . ILE A 1 219 ? 152.949 90.336  145.924 1.00 124.12 ? 219 ILE A CB  1 
ATOM   1610 C CG1 . ILE A 1 219 ? 154.440 89.995  145.948 1.00 122.69 ? 219 ILE A CG1 1 
ATOM   1611 C CG2 . ILE A 1 219 ? 152.159 89.258  145.199 1.00 120.09 ? 219 ILE A CG2 1 
ATOM   1612 C CD1 . ILE A 1 219 ? 154.747 88.644  146.553 1.00 120.63 ? 219 ILE A CD1 1 
ATOM   1613 N N   . LEU A 1 220 ? 150.491 92.051  146.171 1.00 117.95 ? 220 LEU A N   1 
ATOM   1614 C CA  . LEU A 1 220 ? 149.035 92.131  146.106 1.00 120.17 ? 220 LEU A CA  1 
ATOM   1615 C C   . LEU A 1 220 ? 148.564 93.312  145.270 1.00 120.06 ? 220 LEU A C   1 
ATOM   1616 O O   . LEU A 1 220 ? 147.499 93.242  144.647 1.00 121.55 ? 220 LEU A O   1 
ATOM   1617 C CB  . LEU A 1 220 ? 148.458 92.212  147.524 1.00 122.37 ? 220 LEU A CB  1 
ATOM   1618 C CG  . LEU A 1 220 ? 146.987 92.589  147.731 1.00 121.33 ? 220 LEU A CG  1 
ATOM   1619 C CD1 . LEU A 1 220 ? 146.123 91.347  147.748 1.00 119.86 ? 220 LEU A CD1 1 
ATOM   1620 C CD2 . LEU A 1 220 ? 146.791 93.382  149.012 1.00 118.64 ? 220 LEU A CD2 1 
ATOM   1621 N N   . ASP A 1 221 ? 149.335 94.399  145.231 1.00 107.83 ? 221 ASP A N   1 
ATOM   1622 C CA  . ASP A 1 221 ? 148.938 95.577  144.470 1.00 105.73 ? 221 ASP A CA  1 
ATOM   1623 C C   . ASP A 1 221 ? 149.547 95.608  143.072 1.00 106.68 ? 221 ASP A C   1 
ATOM   1624 O O   . ASP A 1 221 ? 148.811 95.579  142.082 1.00 111.46 ? 221 ASP A O   1 
ATOM   1625 C CB  . ASP A 1 221 ? 149.298 96.847  145.247 1.00 106.37 ? 221 ASP A CB  1 
ATOM   1626 C CG  . ASP A 1 221 ? 148.268 97.185  146.303 1.00 110.34 ? 221 ASP A CG  1 
ATOM   1627 O OD1 . ASP A 1 221 ? 147.368 96.352  146.534 1.00 108.60 ? 221 ASP A OD1 1 
ATOM   1628 O OD2 . ASP A 1 221 ? 148.351 98.280  146.896 1.00 112.71 ? 221 ASP A OD2 1 
ATOM   1629 N N   . ILE A 1 222 ? 150.877 95.656  142.962 1.00 99.75  ? 222 ILE A N   1 
ATOM   1630 C CA  . ILE A 1 222 ? 151.495 95.822  141.651 1.00 103.60 ? 222 ILE A CA  1 
ATOM   1631 C C   . ILE A 1 222 ? 151.212 94.618  140.764 1.00 102.62 ? 222 ILE A C   1 
ATOM   1632 O O   . ILE A 1 222 ? 150.885 94.768  139.581 1.00 103.54 ? 222 ILE A O   1 
ATOM   1633 C CB  . ILE A 1 222 ? 153.007 96.069  141.798 1.00 102.60 ? 222 ILE A CB  1 
ATOM   1634 C CG1 . ILE A 1 222 ? 153.273 97.118  142.874 1.00 100.97 ? 222 ILE A CG1 1 
ATOM   1635 C CG2 . ILE A 1 222 ? 153.599 96.521  140.481 1.00 98.60  ? 222 ILE A CG2 1 
ATOM   1636 C CD1 . ILE A 1 222 ? 154.722 97.515  142.986 1.00 98.39  ? 222 ILE A CD1 1 
ATOM   1637 N N   . LEU A 1 223 ? 151.328 93.407  141.310 1.00 102.74 ? 223 LEU A N   1 
ATOM   1638 C CA  . LEU A 1 223 ? 151.220 92.230  140.457 1.00 102.76 ? 223 LEU A CA  1 
ATOM   1639 C C   . LEU A 1 223 ? 149.770 91.825  140.234 1.00 102.43 ? 223 LEU A C   1 
ATOM   1640 O O   . LEU A 1 223 ? 149.357 91.585  139.096 1.00 107.08 ? 223 LEU A O   1 
ATOM   1641 C CB  . LEU A 1 223 ? 152.013 91.070  141.057 1.00 104.29 ? 223 LEU A CB  1 
ATOM   1642 C CG  . LEU A 1 223 ? 153.528 91.263  141.104 1.00 105.08 ? 223 LEU A CG  1 
ATOM   1643 C CD1 . LEU A 1 223 ? 154.222 89.941  141.370 1.00 104.76 ? 223 LEU A CD1 1 
ATOM   1644 C CD2 . LEU A 1 223 ? 154.025 91.881  139.810 1.00 101.83 ? 223 LEU A CD2 1 
ATOM   1645 N N   . LEU A 1 224 ? 148.977 91.746  141.300 1.00 96.97  ? 224 LEU A N   1 
ATOM   1646 C CA  . LEU A 1 224 ? 147.629 91.206  141.161 1.00 97.66  ? 224 LEU A CA  1 
ATOM   1647 C C   . LEU A 1 224 ? 146.588 92.298  140.929 1.00 97.16  ? 224 LEU A C   1 
ATOM   1648 O O   . LEU A 1 224 ? 145.967 92.346  139.866 1.00 99.53  ? 224 LEU A O   1 
ATOM   1649 C CB  . LEU A 1 224 ? 147.272 90.371  142.394 1.00 101.47 ? 224 LEU A CB  1 
ATOM   1650 C CG  . LEU A 1 224 ? 148.198 89.184  142.663 1.00 104.15 ? 224 LEU A CG  1 
ATOM   1651 C CD1 . LEU A 1 224 ? 147.570 88.230  143.667 1.00 104.34 ? 224 LEU A CD1 1 
ATOM   1652 C CD2 . LEU A 1 224 ? 148.538 88.461  141.370 1.00 100.25 ? 224 LEU A CD2 1 
ATOM   1653 N N   . CYS A 1 225 ? 146.408 93.197  141.895 1.00 97.76  ? 225 CYS A N   1 
ATOM   1654 C CA  . CYS A 1 225 ? 145.350 94.196  141.788 1.00 98.30  ? 225 CYS A CA  1 
ATOM   1655 C C   . CYS A 1 225 ? 145.574 95.136  140.609 1.00 98.04  ? 225 CYS A C   1 
ATOM   1656 O O   . CYS A 1 225 ? 144.796 95.131  139.649 1.00 100.59 ? 225 CYS A O   1 
ATOM   1657 C CB  . CYS A 1 225 ? 145.242 95.005  143.082 1.00 101.35 ? 225 CYS A CB  1 
ATOM   1658 S SG  . CYS A 1 225 ? 144.465 94.135  144.459 1.00 105.68 ? 225 CYS A SG  1 
ATOM   1659 N N   . ASN A 1 226 ? 146.640 95.936  140.669 1.00 93.03  ? 226 ASN A N   1 
ATOM   1660 C CA  . ASN A 1 226 ? 146.885 96.919  139.620 1.00 87.45  ? 226 ASN A CA  1 
ATOM   1661 C C   . ASN A 1 226 ? 147.174 96.247  138.285 1.00 93.20  ? 226 ASN A C   1 
ATOM   1662 O O   . ASN A 1 226 ? 146.682 96.694  137.245 1.00 95.61  ? 226 ASN A O   1 
ATOM   1663 C CB  . ASN A 1 226 ? 148.040 97.838  140.015 1.00 88.15  ? 226 ASN A CB  1 
ATOM   1664 C CG  . ASN A 1 226 ? 147.929 98.334  141.441 1.00 93.02  ? 226 ASN A CG  1 
ATOM   1665 O OD1 . ASN A 1 226 ? 146.884 98.209  142.075 1.00 94.63  ? 226 ASN A OD1 1 
ATOM   1666 N ND2 . ASN A 1 226 ? 149.010 98.905  141.953 1.00 92.12  ? 226 ASN A ND2 1 
ATOM   1667 N N   . GLY A 1 227 ? 147.972 95.179  138.292 1.00 94.09  ? 227 GLY A N   1 
ATOM   1668 C CA  . GLY A 1 227 ? 148.301 94.509  137.043 1.00 91.08  ? 227 GLY A CA  1 
ATOM   1669 C C   . GLY A 1 227 ? 147.084 93.909  136.368 1.00 88.19  ? 227 GLY A C   1 
ATOM   1670 O O   . GLY A 1 227 ? 146.881 94.074  135.162 1.00 90.50  ? 227 GLY A O   1 
ATOM   1671 N N   . GLY A 1 228 ? 146.253 93.208  137.139 1.00 76.83  ? 228 GLY A N   1 
ATOM   1672 C CA  . GLY A 1 228 ? 145.037 92.651  136.579 1.00 78.45  ? 228 GLY A CA  1 
ATOM   1673 C C   . GLY A 1 228 ? 144.079 93.720  136.095 1.00 76.21  ? 228 GLY A C   1 
ATOM   1674 O O   . GLY A 1 228 ? 143.461 93.578  135.038 1.00 83.30  ? 228 GLY A O   1 
ATOM   1675 N N   . GLY A 1 229 ? 143.940 94.804  136.860 1.00 78.66  ? 229 GLY A N   1 
ATOM   1676 C CA  . GLY A 1 229 ? 143.081 95.887  136.419 1.00 77.64  ? 229 GLY A CA  1 
ATOM   1677 C C   . GLY A 1 229 ? 143.553 96.500  135.118 1.00 81.19  ? 229 GLY A C   1 
ATOM   1678 O O   . GLY A 1 229 ? 142.756 96.738  134.209 1.00 89.20  ? 229 GLY A O   1 
ATOM   1679 N N   . ILE A 1 230 ? 144.858 96.750  135.005 1.00 76.94  ? 230 ILE A N   1 
ATOM   1680 C CA  . ILE A 1 230 ? 145.400 97.329  133.782 1.00 76.68  ? 230 ILE A CA  1 
ATOM   1681 C C   . ILE A 1 230 ? 145.201 96.378  132.611 1.00 78.72  ? 230 ILE A C   1 
ATOM   1682 O O   . ILE A 1 230 ? 144.821 96.799  131.514 1.00 79.36  ? 230 ILE A O   1 
ATOM   1683 C CB  . ILE A 1 230 ? 146.881 97.697  133.974 1.00 73.38  ? 230 ILE A CB  1 
ATOM   1684 C CG1 . ILE A 1 230 ? 147.016 98.835  134.979 1.00 70.28  ? 230 ILE A CG1 1 
ATOM   1685 C CG2 . ILE A 1 230 ? 147.499 98.112  132.662 1.00 75.57  ? 230 ILE A CG2 1 
ATOM   1686 C CD1 . ILE A 1 230 ? 148.443 99.170  135.309 1.00 73.85  ? 230 ILE A CD1 1 
ATOM   1687 N N   . TRP A 1 231 ? 145.444 95.082  132.821 1.00 72.25  ? 231 TRP A N   1 
ATOM   1688 C CA  . TRP A 1 231 ? 145.270 94.116  131.741 1.00 68.37  ? 231 TRP A CA  1 
ATOM   1689 C C   . TRP A 1 231 ? 143.821 94.070  131.270 1.00 71.54  ? 231 TRP A C   1 
ATOM   1690 O O   . TRP A 1 231 ? 143.547 94.087  130.063 1.00 78.79  ? 231 TRP A O   1 
ATOM   1691 C CB  . TRP A 1 231 ? 145.727 92.733  132.201 1.00 68.69  ? 231 TRP A CB  1 
ATOM   1692 C CG  . TRP A 1 231 ? 145.971 91.768  131.086 1.00 72.41  ? 231 TRP A CG  1 
ATOM   1693 C CD1 . TRP A 1 231 ? 145.590 91.902  129.787 1.00 76.06  ? 231 TRP A CD1 1 
ATOM   1694 C CD2 . TRP A 1 231 ? 146.658 90.516  131.174 1.00 74.82  ? 231 TRP A CD2 1 
ATOM   1695 N NE1 . TRP A 1 231 ? 145.994 90.813  129.059 1.00 75.09  ? 231 TRP A NE1 1 
ATOM   1696 C CE2 . TRP A 1 231 ? 146.654 89.947  129.889 1.00 77.25  ? 231 TRP A CE2 1 
ATOM   1697 C CE3 . TRP A 1 231 ? 147.277 89.821  132.217 1.00 73.85  ? 231 TRP A CE3 1 
ATOM   1698 C CZ2 . TRP A 1 231 ? 147.243 88.717  129.616 1.00 81.08  ? 231 TRP A CZ2 1 
ATOM   1699 C CZ3 . TRP A 1 231 ? 147.861 88.601  131.945 1.00 72.95  ? 231 TRP A CZ3 1 
ATOM   1700 C CH2 . TRP A 1 231 ? 147.840 88.060  130.656 1.00 79.19  ? 231 TRP A CH2 1 
ATOM   1701 N N   . LEU A 1 232 ? 142.877 94.001  132.211 1.00 73.28  ? 232 LEU A N   1 
ATOM   1702 C CA  . LEU A 1 232 ? 141.470 93.949  131.832 1.00 73.98  ? 232 LEU A CA  1 
ATOM   1703 C C   . LEU A 1 232 ? 141.050 95.220  131.112 1.00 73.81  ? 232 LEU A C   1 
ATOM   1704 O O   . LEU A 1 232 ? 140.366 95.163  130.082 1.00 83.40  ? 232 LEU A O   1 
ATOM   1705 C CB  . LEU A 1 232 ? 140.600 93.721  133.064 1.00 76.77  ? 232 LEU A CB  1 
ATOM   1706 C CG  . LEU A 1 232 ? 139.100 93.900  132.837 1.00 75.57  ? 232 LEU A CG  1 
ATOM   1707 C CD1 . LEU A 1 232 ? 138.577 92.825  131.906 1.00 75.93  ? 232 LEU A CD1 1 
ATOM   1708 C CD2 . LEU A 1 232 ? 138.346 93.888  134.151 1.00 76.06  ? 232 LEU A CD2 1 
ATOM   1709 N N   . GLY A 1 233 ? 141.454 96.379  131.633 1.00 67.88  ? 233 GLY A N   1 
ATOM   1710 C CA  . GLY A 1 233 ? 141.121 97.625  130.971 1.00 71.86  ? 233 GLY A CA  1 
ATOM   1711 C C   . GLY A 1 233 ? 141.703 97.708  129.575 1.00 77.64  ? 233 GLY A C   1 
ATOM   1712 O O   . GLY A 1 233 ? 141.053 98.196  128.650 1.00 84.26  ? 233 GLY A O   1 
ATOM   1713 N N   . MET A 1 234 ? 142.927 97.212  129.399 1.00 76.26  ? 234 MET A N   1 
ATOM   1714 C CA  . MET A 1 234 ? 143.556 97.262  128.089 1.00 76.90  ? 234 MET A CA  1 
ATOM   1715 C C   . MET A 1 234 ? 142.866 96.344  127.099 1.00 76.69  ? 234 MET A C   1 
ATOM   1716 O O   . MET A 1 234 ? 142.681 96.720  125.940 1.00 76.32  ? 234 MET A O   1 
ATOM   1717 C CB  . MET A 1 234 ? 145.026 96.888  128.200 1.00 75.70  ? 234 MET A CB  1 
ATOM   1718 C CG  . MET A 1 234 ? 145.866 98.009  128.717 1.00 73.26  ? 234 MET A CG  1 
ATOM   1719 S SD  . MET A 1 234 ? 145.680 99.504  127.760 1.00 79.97  ? 234 MET A SD  1 
ATOM   1720 C CE  . MET A 1 234 ? 146.746 100.541 128.730 1.00 81.07  ? 234 MET A CE  1 
ATOM   1721 N N   . VAL A 1 235 ? 142.482 95.142  127.526 1.00 74.30  ? 235 VAL A N   1 
ATOM   1722 C CA  . VAL A 1 235 ? 141.797 94.245  126.602 1.00 74.98  ? 235 VAL A CA  1 
ATOM   1723 C C   . VAL A 1 235 ? 140.420 94.797  126.248 1.00 78.68  ? 235 VAL A C   1 
ATOM   1724 O O   . VAL A 1 235 ? 139.975 94.692  125.097 1.00 84.42  ? 235 VAL A O   1 
ATOM   1725 C CB  . VAL A 1 235 ? 141.733 92.815  127.173 1.00 73.75  ? 235 VAL A CB  1 
ATOM   1726 C CG1 . VAL A 1 235 ? 140.538 92.621  128.089 1.00 72.90  ? 235 VAL A CG1 1 
ATOM   1727 C CG2 . VAL A 1 235 ? 141.708 91.807  126.041 1.00 76.08  ? 235 VAL A CG2 1 
ATOM   1728 N N   . VAL A 1 236 ? 139.740 95.435  127.205 1.00 70.94  ? 236 VAL A N   1 
ATOM   1729 C CA  . VAL A 1 236 ? 138.433 96.008  126.900 1.00 68.50  ? 236 VAL A CA  1 
ATOM   1730 C C   . VAL A 1 236 ? 138.575 97.201  125.961 1.00 75.83  ? 236 VAL A C   1 
ATOM   1731 O O   . VAL A 1 236 ? 137.764 97.385  125.045 1.00 81.36  ? 236 VAL A O   1 
ATOM   1732 C CB  . VAL A 1 236 ? 137.692 96.382  128.194 1.00 68.84  ? 236 VAL A CB  1 
ATOM   1733 C CG1 . VAL A 1 236 ? 136.403 97.103  127.867 1.00 74.70  ? 236 VAL A CG1 1 
ATOM   1734 C CG2 . VAL A 1 236 ? 137.395 95.140  129.003 1.00 72.95  ? 236 VAL A CG2 1 
ATOM   1735 N N   . CYS A 1 237 ? 139.606 98.026  126.162 1.00 79.19  ? 237 CYS A N   1 
ATOM   1736 C CA  . CYS A 1 237 ? 139.850 99.142  125.252 1.00 77.86  ? 237 CYS A CA  1 
ATOM   1737 C C   . CYS A 1 237 ? 140.206 98.649  123.856 1.00 80.25  ? 237 CYS A C   1 
ATOM   1738 O O   . CYS A 1 237 ? 139.761 99.221  122.855 1.00 81.54  ? 237 CYS A O   1 
ATOM   1739 C CB  . CYS A 1 237 ? 140.958 100.037 125.799 1.00 76.98  ? 237 CYS A CB  1 
ATOM   1740 S SG  . CYS A 1 237 ? 141.177 101.575 124.890 1.00 89.47  ? 237 CYS A SG  1 
ATOM   1741 N N   . ARG A 1 238 ? 141.014 97.590  123.771 1.00 84.84  ? 238 ARG A N   1 
ATOM   1742 C CA  . ARG A 1 238 ? 141.332 96.999  122.478 1.00 84.42  ? 238 ARG A CA  1 
ATOM   1743 C C   . ARG A 1 238 ? 140.073 96.515  121.781 1.00 89.04  ? 238 ARG A C   1 
ATOM   1744 O O   . ARG A 1 238 ? 139.904 96.721  120.574 1.00 91.81  ? 238 ARG A O   1 
ATOM   1745 C CB  . ARG A 1 238 ? 142.312 95.842  122.660 1.00 85.66  ? 238 ARG A CB  1 
ATOM   1746 C CG  . ARG A 1 238 ? 143.270 95.632  121.505 1.00 85.85  ? 238 ARG A CG  1 
ATOM   1747 C CD  . ARG A 1 238 ? 144.665 96.142  121.827 1.00 87.76  ? 238 ARG A CD  1 
ATOM   1748 N NE  . ARG A 1 238 ? 145.183 95.608  123.081 1.00 89.19  ? 238 ARG A NE  1 
ATOM   1749 C CZ  . ARG A 1 238 ? 145.566 94.351  123.266 1.00 91.35  ? 238 ARG A CZ  1 
ATOM   1750 N NH1 . ARG A 1 238 ? 145.526 93.463  122.286 1.00 90.06  ? 238 ARG A NH1 1 
ATOM   1751 N NH2 . ARG A 1 238 ? 146.004 93.977  124.464 1.00 90.63  ? 238 ARG A NH2 1 
ATOM   1752 N N   . PHE A 1 239 ? 139.178 95.864  122.525 1.00 87.95  ? 239 PHE A N   1 
ATOM   1753 C CA  . PHE A 1 239 ? 137.909 95.438  121.947 1.00 85.31  ? 239 PHE A CA  1 
ATOM   1754 C C   . PHE A 1 239 ? 137.117 96.631  121.431 1.00 86.51  ? 239 PHE A C   1 
ATOM   1755 O O   . PHE A 1 239 ? 136.649 96.634  120.287 1.00 91.81  ? 239 PHE A O   1 
ATOM   1756 C CB  . PHE A 1 239 ? 137.098 94.666  122.986 1.00 81.12  ? 239 PHE A CB  1 
ATOM   1757 C CG  . PHE A 1 239 ? 135.851 94.037  122.438 1.00 84.37  ? 239 PHE A CG  1 
ATOM   1758 C CD1 . PHE A 1 239 ? 135.725 93.771  121.086 1.00 90.06  ? 239 PHE A CD1 1 
ATOM   1759 C CD2 . PHE A 1 239 ? 134.797 93.727  123.277 1.00 86.06  ? 239 PHE A CD2 1 
ATOM   1760 C CE1 . PHE A 1 239 ? 134.576 93.199  120.584 1.00 90.65  ? 239 PHE A CE1 1 
ATOM   1761 C CE2 . PHE A 1 239 ? 133.647 93.154  122.781 1.00 91.84  ? 239 PHE A CE2 1 
ATOM   1762 C CZ  . PHE A 1 239 ? 133.536 92.890  121.432 1.00 91.53  ? 239 PHE A CZ  1 
ATOM   1763 N N   . LEU A 1 240 ? 136.971 97.664  122.259 1.00 82.57  ? 240 LEU A N   1 
ATOM   1764 C CA  . LEU A 1 240 ? 136.118 98.791  121.896 1.00 84.63  ? 240 LEU A CA  1 
ATOM   1765 C C   . LEU A 1 240 ? 136.673 99.570  120.711 1.00 86.84  ? 240 LEU A C   1 
ATOM   1766 O O   . LEU A 1 240 ? 135.899 100.119 119.920 1.00 87.20  ? 240 LEU A O   1 
ATOM   1767 C CB  . LEU A 1 240 ? 135.932 99.714  123.097 1.00 80.13  ? 240 LEU A CB  1 
ATOM   1768 C CG  . LEU A 1 240 ? 134.661 99.491  123.911 1.00 74.50  ? 240 LEU A CG  1 
ATOM   1769 C CD1 . LEU A 1 240 ? 134.620 98.078  124.453 1.00 83.42  ? 240 LEU A CD1 1 
ATOM   1770 C CD2 . LEU A 1 240 ? 134.600 100.484 125.041 1.00 72.57  ? 240 LEU A CD2 1 
ATOM   1771 N N   . GLU A 1 241 ? 137.997 99.645  120.579 1.00 94.39  ? 241 GLU A N   1 
ATOM   1772 C CA  . GLU A 1 241 ? 138.578 100.405 119.477 1.00 94.31  ? 241 GLU A CA  1 
ATOM   1773 C C   . GLU A 1 241 ? 138.281 99.759  118.130 1.00 97.01  ? 241 GLU A C   1 
ATOM   1774 O O   . GLU A 1 241 ? 137.963 100.456 117.161 1.00 98.44  ? 241 GLU A O   1 
ATOM   1775 C CB  . GLU A 1 241 ? 140.083 100.555 119.679 1.00 92.94  ? 241 GLU A CB  1 
ATOM   1776 C CG  . GLU A 1 241 ? 140.464 101.732 120.548 1.00 94.63  ? 241 GLU A CG  1 
ATOM   1777 C CD  . GLU A 1 241 ? 141.960 101.925 120.633 1.00 99.50  ? 241 GLU A CD  1 
ATOM   1778 O OE1 . GLU A 1 241 ? 142.674 101.403 119.751 1.00 100.13 ? 241 GLU A OE1 1 
ATOM   1779 O OE2 . GLU A 1 241 ? 142.423 102.599 121.577 1.00 96.92  ? 241 GLU A OE2 1 
ATOM   1780 N N   . MET A 1 242 ? 138.380 98.435  118.044 1.00 97.15  ? 242 MET A N   1 
ATOM   1781 C CA  . MET A 1 242 ? 138.130 97.730  116.794 1.00 96.54  ? 242 MET A CA  1 
ATOM   1782 C C   . MET A 1 242 ? 136.688 97.270  116.638 1.00 100.67 ? 242 MET A C   1 
ATOM   1783 O O   . MET A 1 242 ? 136.387 96.546  115.685 1.00 103.14 ? 242 MET A O   1 
ATOM   1784 C CB  . MET A 1 242 ? 139.063 96.524  116.655 1.00 98.16  ? 242 MET A CB  1 
ATOM   1785 C CG  . MET A 1 242 ? 140.511 96.793  117.009 1.00 102.61 ? 242 MET A CG  1 
ATOM   1786 S SD  . MET A 1 242 ? 141.483 95.276  116.966 1.00 119.79 ? 242 MET A SD  1 
ATOM   1787 C CE  . MET A 1 242 ? 142.867 95.726  118.003 1.00 101.60 ? 242 MET A CE  1 
ATOM   1788 N N   . ARG A 1 243 ? 135.800 97.654  117.546 1.00 94.76  ? 243 ARG A N   1 
ATOM   1789 C CA  . ARG A 1 243 ? 134.391 97.324  117.405 1.00 92.32  ? 243 ARG A CA  1 
ATOM   1790 C C   . ARG A 1 243 ? 133.681 98.388  116.578 1.00 95.35  ? 243 ARG A C   1 
ATOM   1791 O O   . ARG A 1 243 ? 133.868 99.588  116.793 1.00 94.87  ? 243 ARG A O   1 
ATOM   1792 C CB  . ARG A 1 243 ? 133.736 97.196  118.780 1.00 91.90  ? 243 ARG A CB  1 
ATOM   1793 C CG  . ARG A 1 243 ? 132.228 97.308  118.761 1.00 94.87  ? 243 ARG A CG  1 
ATOM   1794 C CD  . ARG A 1 243 ? 131.677 97.623  120.142 1.00 94.94  ? 243 ARG A CD  1 
ATOM   1795 N NE  . ARG A 1 243 ? 130.240 97.868  120.113 1.00 95.31  ? 243 ARG A NE  1 
ATOM   1796 C CZ  . ARG A 1 243 ? 129.320 96.938  119.896 1.00 96.58  ? 243 ARG A CZ  1 
ATOM   1797 N NH1 . ARG A 1 243 ? 129.647 95.669  119.714 1.00 97.68  ? 243 ARG A NH1 1 
ATOM   1798 N NH2 . ARG A 1 243 ? 128.038 97.290  119.866 1.00 96.23  ? 243 ARG A NH2 1 
ATOM   1799 N N   . THR A 1 244 ? 132.874 97.941  115.618 1.00 96.45  ? 244 THR A N   1 
ATOM   1800 C CA  . THR A 1 244 ? 132.087 98.839  114.785 1.00 96.18  ? 244 THR A CA  1 
ATOM   1801 C C   . THR A 1 244 ? 130.741 99.102  115.444 1.00 96.30  ? 244 THR A C   1 
ATOM   1802 O O   . THR A 1 244 ? 130.105 98.185  115.971 1.00 98.47  ? 244 THR A O   1 
ATOM   1803 C CB  . THR A 1 244 ? 131.873 98.249  113.393 1.00 93.23  ? 244 THR A CB  1 
ATOM   1804 O OG1 . THR A 1 244 ? 130.821 97.279  113.447 1.00 94.58  ? 244 THR A OG1 1 
ATOM   1805 C CG2 . THR A 1 244 ? 133.143 97.577  112.905 1.00 92.10  ? 244 THR A CG2 1 
ATOM   1806 N N   . TYR A 1 245 ? 130.308 100.357 115.407 1.00 85.16  ? 245 TYR A N   1 
ATOM   1807 C CA  . TYR A 1 245 ? 129.131 100.799 116.143 1.00 85.88  ? 245 TYR A CA  1 
ATOM   1808 C C   . TYR A 1 245 ? 127.956 100.965 115.188 1.00 91.70  ? 245 TYR A C   1 
ATOM   1809 O O   . TYR A 1 245 ? 128.019 101.763 114.247 1.00 93.46  ? 245 TYR A O   1 
ATOM   1810 C CB  . TYR A 1 245 ? 129.436 102.093 116.892 1.00 84.48  ? 245 TYR A CB  1 
ATOM   1811 C CG  . TYR A 1 245 ? 130.523 101.901 117.923 1.00 85.97  ? 245 TYR A CG  1 
ATOM   1812 C CD1 . TYR A 1 245 ? 130.237 101.354 119.166 1.00 86.29  ? 245 TYR A CD1 1 
ATOM   1813 C CD2 . TYR A 1 245 ? 131.838 102.231 117.643 1.00 90.58  ? 245 TYR A CD2 1 
ATOM   1814 C CE1 . TYR A 1 245 ? 131.224 101.162 120.105 1.00 83.98  ? 245 TYR A CE1 1 
ATOM   1815 C CE2 . TYR A 1 245 ? 132.832 102.040 118.578 1.00 91.51  ? 245 TYR A CE2 1 
ATOM   1816 C CZ  . TYR A 1 245 ? 132.519 101.505 119.805 1.00 89.78  ? 245 TYR A CZ  1 
ATOM   1817 O OH  . TYR A 1 245 ? 133.507 101.314 120.739 1.00 94.04  ? 245 TYR A OH  1 
ATOM   1818 N N   . HIS A 1 246 ? 126.887 100.214 115.440 1.00 97.26  ? 246 HIS A N   1 
ATOM   1819 C CA  . HIS A 1 246 ? 125.726 100.100 114.562 1.00 96.75  ? 246 HIS A CA  1 
ATOM   1820 C C   . HIS A 1 246 ? 124.452 100.391 115.367 1.00 96.98  ? 246 HIS A C   1 
ATOM   1821 O O   . HIS A 1 246 ? 123.494 99.619  115.420 1.00 98.42  ? 246 HIS A O   1 
ATOM   1822 C CB  . HIS A 1 246 ? 125.782 98.728  113.867 1.00 98.86  ? 246 HIS A CB  1 
ATOM   1823 C CG  . HIS A 1 246 ? 124.450 98.126  113.544 1.00 102.37 ? 246 HIS A CG  1 
ATOM   1824 N ND1 . HIS A 1 246 ? 123.490 98.791  112.813 1.00 100.10 ? 246 HIS A ND1 1 
ATOM   1825 C CD2 . HIS A 1 246 ? 123.913 96.926  113.866 1.00 99.46  ? 246 HIS A CD2 1 
ATOM   1826 C CE1 . HIS A 1 246 ? 122.421 98.024  112.693 1.00 99.43  ? 246 HIS A CE1 1 
ATOM   1827 N NE2 . HIS A 1 246 ? 122.652 96.887  113.323 1.00 100.94 ? 246 HIS A NE2 1 
ATOM   1828 N N   . TRP A 1 247 ? 124.462 101.520 116.066 1.00 83.77  ? 247 TRP A N   1 
ATOM   1829 C CA  . TRP A 1 247 ? 123.324 101.890 116.896 1.00 83.97  ? 247 TRP A CA  1 
ATOM   1830 C C   . TRP A 1 247 ? 122.097 102.159 116.039 1.00 83.67  ? 247 TRP A C   1 
ATOM   1831 O O   . TRP A 1 247 ? 122.083 103.089 115.227 1.00 81.20  ? 247 TRP A O   1 
ATOM   1832 C CB  . TRP A 1 247 ? 123.675 103.113 117.737 1.00 80.48  ? 247 TRP A CB  1 
ATOM   1833 C CG  . TRP A 1 247 ? 124.878 102.879 118.563 1.00 74.53  ? 247 TRP A CG  1 
ATOM   1834 C CD1 . TRP A 1 247 ? 126.088 103.475 118.430 1.00 75.46  ? 247 TRP A CD1 1 
ATOM   1835 C CD2 . TRP A 1 247 ? 125.001 101.951 119.643 1.00 75.91  ? 247 TRP A CD2 1 
ATOM   1836 N NE1 . TRP A 1 247 ? 126.959 102.985 119.366 1.00 78.18  ? 247 TRP A NE1 1 
ATOM   1837 C CE2 . TRP A 1 247 ? 126.314 102.047 120.125 1.00 75.39  ? 247 TRP A CE2 1 
ATOM   1838 C CE3 . TRP A 1 247 ? 124.123 101.053 120.252 1.00 80.01  ? 247 TRP A CE3 1 
ATOM   1839 C CZ2 . TRP A 1 247 ? 126.774 101.280 121.188 1.00 76.29  ? 247 TRP A CZ2 1 
ATOM   1840 C CZ3 . TRP A 1 247 ? 124.580 100.294 121.305 1.00 77.47  ? 247 TRP A CZ3 1 
ATOM   1841 C CH2 . TRP A 1 247 ? 125.892 100.411 121.764 1.00 77.17  ? 247 TRP A CH2 1 
ATOM   1842 N N   . ALA A 1 248 ? 121.070 101.337 116.224 1.00 88.71  ? 248 ALA A N   1 
ATOM   1843 C CA  . ALA A 1 248 ? 119.805 101.469 115.523 1.00 87.82  ? 248 ALA A CA  1 
ATOM   1844 C C   . ALA A 1 248 ? 118.760 102.067 116.452 1.00 90.99  ? 248 ALA A C   1 
ATOM   1845 O O   . ALA A 1 248 ? 118.956 102.163 117.666 1.00 93.26  ? 248 ALA A O   1 
ATOM   1846 C CB  . ALA A 1 248 ? 119.321 100.115 114.996 1.00 88.70  ? 248 ALA A CB  1 
ATOM   1847 N N   . SER A 1 249 ? 117.642 102.476 115.863 1.00 106.71 ? 249 SER A N   1 
ATOM   1848 C CA  . SER A 1 249 ? 116.566 103.060 116.649 1.00 109.26 ? 249 SER A CA  1 
ATOM   1849 C C   . SER A 1 249 ? 115.941 102.014 117.562 1.00 109.33 ? 249 SER A C   1 
ATOM   1850 O O   . SER A 1 249 ? 115.711 100.871 117.160 1.00 108.24 ? 249 SER A O   1 
ATOM   1851 C CB  . SER A 1 249 ? 115.501 103.654 115.730 1.00 107.37 ? 249 SER A CB  1 
ATOM   1852 O OG  . SER A 1 249 ? 114.340 103.993 116.465 1.00 110.22 ? 249 SER A OG  1 
ATOM   1853 N N   . PHE A 1 250 ? 115.670 102.414 118.805 1.00 97.54  ? 250 PHE A N   1 
ATOM   1854 C CA  . PHE A 1 250 ? 114.995 101.516 119.734 1.00 95.87  ? 250 PHE A CA  1 
ATOM   1855 C C   . PHE A 1 250 ? 113.609 101.144 119.232 1.00 98.29  ? 250 PHE A C   1 
ATOM   1856 O O   . PHE A 1 250 ? 113.126 100.038 119.500 1.00 99.91  ? 250 PHE A O   1 
ATOM   1857 C CB  . PHE A 1 250 ? 114.915 102.167 121.115 1.00 96.79  ? 250 PHE A CB  1 
ATOM   1858 C CG  . PHE A 1 250 ? 114.258 101.312 122.161 1.00 98.65  ? 250 PHE A CG  1 
ATOM   1859 C CD1 . PHE A 1 250 ? 112.896 101.389 122.386 1.00 98.39  ? 250 PHE A CD1 1 
ATOM   1860 C CD2 . PHE A 1 250 ? 115.006 100.446 122.933 1.00 98.25  ? 250 PHE A CD2 1 
ATOM   1861 C CE1 . PHE A 1 250 ? 112.295 100.613 123.350 1.00 97.57  ? 250 PHE A CE1 1 
ATOM   1862 C CE2 . PHE A 1 250 ? 114.408 99.668  123.898 1.00 97.44  ? 250 PHE A CE2 1 
ATOM   1863 C CZ  . PHE A 1 250 ? 113.051 99.753  124.106 1.00 97.56  ? 250 PHE A CZ  1 
ATOM   1864 N N   . LYS A 1 251 ? 112.955 102.051 118.505 1.00 106.05 ? 251 LYS A N   1 
ATOM   1865 C CA  . LYS A 1 251 ? 111.625 101.763 117.980 1.00 106.68 ? 251 LYS A CA  1 
ATOM   1866 C C   . LYS A 1 251 ? 111.681 100.743 116.850 1.00 105.13 ? 251 LYS A C   1 
ATOM   1867 O O   . LYS A 1 251 ? 110.830 99.851  116.771 1.00 106.50 ? 251 LYS A O   1 
ATOM   1868 C CB  . LYS A 1 251 ? 110.963 103.054 117.504 1.00 104.94 ? 251 LYS A CB  1 
ATOM   1869 C CG  . LYS A 1 251 ? 110.943 104.157 118.548 1.00 103.38 ? 251 LYS A CG  1 
ATOM   1870 C CD  . LYS A 1 251 ? 110.750 105.526 117.916 1.00 102.95 ? 251 LYS A CD  1 
ATOM   1871 C CE  . LYS A 1 251 ? 111.569 105.671 116.646 1.00 104.66 ? 251 LYS A CE  1 
ATOM   1872 N NZ  . LYS A 1 251 ? 111.676 107.091 116.215 1.00 106.95 ? 251 LYS A NZ  1 
ATOM   1873 N N   . ASP A 1 252 ? 112.674 100.858 115.966 1.00 106.72 ? 252 ASP A N   1 
ATOM   1874 C CA  . ASP A 1 252 ? 112.728 99.982  114.802 1.00 108.45 ? 252 ASP A CA  1 
ATOM   1875 C C   . ASP A 1 252 ? 112.940 98.527  115.194 1.00 110.72 ? 252 ASP A C   1 
ATOM   1876 O O   . ASP A 1 252 ? 112.463 97.625  114.496 1.00 112.67 ? 252 ASP A O   1 
ATOM   1877 C CB  . ASP A 1 252 ? 113.828 100.442 113.848 1.00 111.16 ? 252 ASP A CB  1 
ATOM   1878 C CG  . ASP A 1 252 ? 113.302 101.340 112.745 1.00 114.25 ? 252 ASP A CG  1 
ATOM   1879 O OD1 . ASP A 1 252 ? 112.175 101.096 112.267 1.00 114.67 ? 252 ASP A OD1 1 
ATOM   1880 O OD2 . ASP A 1 252 ? 114.012 102.291 112.358 1.00 115.35 ? 252 ASP A OD2 1 
ATOM   1881 N N   . ILE A 1 253 ? 113.651 98.275  116.295 1.00 108.66 ? 253 ILE A N   1 
ATOM   1882 C CA  . ILE A 1 253 ? 113.835 96.907  116.759 1.00 111.35 ? 253 ILE A CA  1 
ATOM   1883 C C   . ILE A 1 253 ? 112.485 96.333  117.165 1.00 111.10 ? 253 ILE A C   1 
ATOM   1884 O O   . ILE A 1 253 ? 111.666 97.009  117.798 1.00 109.04 ? 253 ILE A O   1 
ATOM   1885 C CB  . ILE A 1 253 ? 114.848 96.869  117.917 1.00 111.09 ? 253 ILE A CB  1 
ATOM   1886 C CG1 . ILE A 1 253 ? 116.270 97.010  117.379 1.00 108.75 ? 253 ILE A CG1 1 
ATOM   1887 C CG2 . ILE A 1 253 ? 114.729 95.581  118.706 1.00 107.66 ? 253 ILE A CG2 1 
ATOM   1888 C CD1 . ILE A 1 253 ? 116.606 96.020  116.286 1.00 108.10 ? 253 ILE A CD1 1 
ATOM   1889 N N   . HIS A 1 254 ? 112.236 95.082  116.779 1.00 112.50 ? 254 HIS A N   1 
ATOM   1890 C CA  . HIS A 1 254 ? 110.946 94.442  117.007 1.00 113.19 ? 254 HIS A CA  1 
ATOM   1891 C C   . HIS A 1 254 ? 110.961 93.458  118.170 1.00 112.70 ? 254 HIS A C   1 
ATOM   1892 O O   . HIS A 1 254 ? 110.124 93.556  119.072 1.00 111.97 ? 254 HIS A O   1 
ATOM   1893 C CB  . HIS A 1 254 ? 110.486 93.730  115.731 1.00 112.89 ? 254 HIS A CB  1 
ATOM   1894 C CG  . HIS A 1 254 ? 110.059 94.664  114.643 1.00 113.63 ? 254 HIS A CG  1 
ATOM   1895 N ND1 . HIS A 1 254 ? 109.839 96.007  114.861 1.00 113.59 ? 254 HIS A ND1 1 
ATOM   1896 C CD2 . HIS A 1 254 ? 109.809 94.450  113.330 1.00 111.60 ? 254 HIS A CD2 1 
ATOM   1897 C CE1 . HIS A 1 254 ? 109.474 96.580  113.729 1.00 111.55 ? 254 HIS A CE1 1 
ATOM   1898 N NE2 . HIS A 1 254 ? 109.448 95.657  112.784 1.00 112.25 ? 254 HIS A NE2 1 
ATOM   1899 N N   . THR A 1 255 ? 111.890 92.507  118.167 1.00 114.96 ? 255 THR A N   1 
ATOM   1900 C CA  . THR A 1 255 ? 111.904 91.464  119.182 1.00 115.66 ? 255 THR A CA  1 
ATOM   1901 C C   . THR A 1 255 ? 112.178 92.045  120.564 1.00 111.93 ? 255 THR A C   1 
ATOM   1902 O O   . THR A 1 255 ? 112.933 93.007  120.722 1.00 111.33 ? 255 THR A O   1 
ATOM   1903 C CB  . THR A 1 255 ? 112.956 90.409  118.848 1.00 115.27 ? 255 THR A CB  1 
ATOM   1904 O OG1 . THR A 1 255 ? 114.228 90.826  119.357 1.00 117.13 ? 255 THR A OG1 1 
ATOM   1905 C CG2 . THR A 1 255 ? 113.057 90.220  117.344 1.00 111.79 ? 255 THR A CG2 1 
ATOM   1906 N N   . THR A 1 256 ? 111.545 91.445  121.574 1.00 114.45 ? 256 THR A N   1 
ATOM   1907 C CA  . THR A 1 256 ? 111.714 91.922  122.943 1.00 119.13 ? 256 THR A CA  1 
ATOM   1908 C C   . THR A 1 256 ? 113.156 91.772  123.406 1.00 116.93 ? 256 THR A C   1 
ATOM   1909 O O   . THR A 1 256 ? 113.697 92.661  124.075 1.00 115.99 ? 256 THR A O   1 
ATOM   1910 C CB  . THR A 1 256 ? 110.774 91.170  123.884 1.00 118.32 ? 256 THR A CB  1 
ATOM   1911 O OG1 . THR A 1 256 ? 111.317 89.876  124.172 1.00 117.55 ? 256 THR A OG1 1 
ATOM   1912 C CG2 . THR A 1 256 ? 109.402 91.009  123.246 1.00 114.71 ? 256 THR A CG2 1 
ATOM   1913 N N   . THR A 1 257 ? 113.794 90.651  123.067 1.00 108.69 ? 257 THR A N   1 
ATOM   1914 C CA  . THR A 1 257 ? 115.197 90.473  123.422 1.00 109.72 ? 257 THR A CA  1 
ATOM   1915 C C   . THR A 1 257 ? 116.067 91.534  122.761 1.00 110.03 ? 257 THR A C   1 
ATOM   1916 O O   . THR A 1 257 ? 117.006 92.048  123.378 1.00 108.87 ? 257 THR A O   1 
ATOM   1917 C CB  . THR A 1 257 ? 115.666 89.067  123.047 1.00 111.91 ? 257 THR A CB  1 
ATOM   1918 O OG1 . THR A 1 257 ? 117.071 88.944  123.301 1.00 113.04 ? 257 THR A OG1 1 
ATOM   1919 C CG2 . THR A 1 257 ? 115.376 88.760  121.582 1.00 108.59 ? 257 THR A CG2 1 
ATOM   1920 N N   . GLY A 1 258 ? 115.761 91.885  121.511 1.00 107.87 ? 258 GLY A N   1 
ATOM   1921 C CA  . GLY A 1 258 ? 116.500 92.949  120.853 1.00 106.92 ? 258 GLY A CA  1 
ATOM   1922 C C   . GLY A 1 258 ? 116.303 94.294  121.525 1.00 106.32 ? 258 GLY A C   1 
ATOM   1923 O O   . GLY A 1 258 ? 117.249 95.069  121.671 1.00 106.10 ? 258 GLY A O   1 
ATOM   1924 N N   . LYS A 1 259 ? 115.070 94.588  121.944 1.00 104.28 ? 259 LYS A N   1 
ATOM   1925 C CA  . LYS A 1 259 ? 114.814 95.836  122.655 1.00 104.62 ? 259 LYS A CA  1 
ATOM   1926 C C   . LYS A 1 259 ? 115.584 95.885  123.967 1.00 103.08 ? 259 LYS A C   1 
ATOM   1927 O O   . LYS A 1 259 ? 116.168 96.918  124.315 1.00 104.66 ? 259 LYS A O   1 
ATOM   1928 C CB  . LYS A 1 259 ? 113.318 95.998  122.912 1.00 104.01 ? 259 LYS A CB  1 
ATOM   1929 C CG  . LYS A 1 259 ? 112.499 96.304  121.675 1.00 101.59 ? 259 LYS A CG  1 
ATOM   1930 C CD  . LYS A 1 259 ? 111.540 97.446  121.932 1.00 101.08 ? 259 LYS A CD  1 
ATOM   1931 C CE  . LYS A 1 259 ? 110.678 97.720  120.722 1.00 102.00 ? 259 LYS A CE  1 
ATOM   1932 N NZ  . LYS A 1 259 ? 110.649 96.550  119.805 1.00 102.18 ? 259 LYS A NZ  1 
ATOM   1933 N N   . ILE A 1 260 ? 115.598 94.776  124.707 1.00 94.11  ? 260 ILE A N   1 
ATOM   1934 C CA  . ILE A 1 260 ? 116.337 94.731  125.965 1.00 93.90  ? 260 ILE A CA  1 
ATOM   1935 C C   . ILE A 1 260 ? 117.827 94.916  125.715 1.00 94.58  ? 260 ILE A C   1 
ATOM   1936 O O   . ILE A 1 260 ? 118.508 95.651  126.441 1.00 94.60  ? 260 ILE A O   1 
ATOM   1937 C CB  . ILE A 1 260 ? 116.046 93.415  126.705 1.00 95.89  ? 260 ILE A CB  1 
ATOM   1938 C CG1 . ILE A 1 260 ? 114.584 93.370  127.145 1.00 98.98  ? 260 ILE A CG1 1 
ATOM   1939 C CG2 . ILE A 1 260 ? 116.965 93.263  127.899 1.00 96.21  ? 260 ILE A CG2 1 
ATOM   1940 C CD1 . ILE A 1 260 ? 114.104 94.650  127.793 1.00 96.60  ? 260 ILE A CD1 1 
ATOM   1941 N N   . LYS A 1 261 ? 118.357 94.251  124.687 1.00 93.46  ? 261 LYS A N   1 
ATOM   1942 C CA  . LYS A 1 261 ? 119.772 94.389  124.365 1.00 93.07  ? 261 LYS A CA  1 
ATOM   1943 C C   . LYS A 1 261 ? 120.109 95.825  123.996 1.00 93.85  ? 261 LYS A C   1 
ATOM   1944 O O   . LYS A 1 261 ? 121.148 96.353  124.406 1.00 96.88  ? 261 LYS A O   1 
ATOM   1945 C CB  . LYS A 1 261 ? 120.144 93.435  123.231 1.00 92.23  ? 261 LYS A CB  1 
ATOM   1946 C CG  . LYS A 1 261 ? 121.371 93.839  122.438 1.00 90.69  ? 261 LYS A CG  1 
ATOM   1947 C CD  . LYS A 1 261 ? 121.809 92.717  121.511 1.00 95.93  ? 261 LYS A CD  1 
ATOM   1948 C CE  . LYS A 1 261 ? 123.185 92.983  120.925 1.00 94.43  ? 261 LYS A CE  1 
ATOM   1949 N NZ  . LYS A 1 261 ? 124.266 92.373  121.747 1.00 93.48  ? 261 LYS A NZ  1 
ATOM   1950 N N   . ARG A 1 262 ? 119.237 96.478  123.227 1.00 83.64  ? 262 ARG A N   1 
ATOM   1951 C CA  . ARG A 1 262 ? 119.465 97.874  122.876 1.00 80.04  ? 262 ARG A CA  1 
ATOM   1952 C C   . ARG A 1 262 ? 119.427 98.763  124.111 1.00 79.87  ? 262 ARG A C   1 
ATOM   1953 O O   . ARG A 1 262 ? 120.231 99.692  124.242 1.00 82.77  ? 262 ARG A O   1 
ATOM   1954 C CB  . ARG A 1 262 ? 118.431 98.330  121.849 1.00 76.69  ? 262 ARG A CB  1 
ATOM   1955 C CG  . ARG A 1 262 ? 118.607 99.756  121.375 1.00 74.81  ? 262 ARG A CG  1 
ATOM   1956 C CD  . ARG A 1 262 ? 120.052 100.079 121.067 1.00 73.23  ? 262 ARG A CD  1 
ATOM   1957 N NE  . ARG A 1 262 ? 120.214 101.486 120.732 1.00 79.13  ? 262 ARG A NE  1 
ATOM   1958 C CZ  . ARG A 1 262 ? 120.288 102.461 121.624 1.00 77.56  ? 262 ARG A CZ  1 
ATOM   1959 N NH1 . ARG A 1 262 ? 120.260 102.213 122.921 1.00 75.00  ? 262 ARG A NH1 1 
ATOM   1960 N NH2 . ARG A 1 262 ? 120.396 103.717 121.205 1.00 80.05  ? 262 ARG A NH2 1 
ATOM   1961 N N   . ALA A 1 263 ? 118.497 98.496  125.028 1.00 76.95  ? 263 ALA A N   1 
ATOM   1962 C CA  . ALA A 1 263 ? 118.399 99.311  126.232 1.00 74.57  ? 263 ALA A CA  1 
ATOM   1963 C C   . ALA A 1 263 ? 119.645 99.170  127.094 1.00 78.47  ? 263 ALA A C   1 
ATOM   1964 O O   . ALA A 1 263 ? 120.221 100.168 127.540 1.00 82.64  ? 263 ALA A O   1 
ATOM   1965 C CB  . ALA A 1 263 ? 117.151 98.930  127.025 1.00 77.71  ? 263 ALA A CB  1 
ATOM   1966 N N   . VAL A 1 264 ? 120.081 97.934  127.337 1.00 81.89  ? 264 VAL A N   1 
ATOM   1967 C CA  . VAL A 1 264 ? 121.232 97.717  128.208 1.00 82.54  ? 264 VAL A CA  1 
ATOM   1968 C C   . VAL A 1 264 ? 122.507 98.240  127.559 1.00 83.54  ? 264 VAL A C   1 
ATOM   1969 O O   . VAL A 1 264 ? 123.348 98.855  128.223 1.00 80.81  ? 264 VAL A O   1 
ATOM   1970 C CB  . VAL A 1 264 ? 121.353 96.229  128.578 1.00 78.83  ? 264 VAL A CB  1 
ATOM   1971 C CG1 . VAL A 1 264 ? 122.565 96.006  129.457 1.00 80.57  ? 264 VAL A CG1 1 
ATOM   1972 C CG2 . VAL A 1 264 ? 120.099 95.759  129.284 1.00 79.21  ? 264 VAL A CG2 1 
ATOM   1973 N N   . LEU A 1 265 ? 122.668 98.015  126.253 1.00 84.30  ? 265 LEU A N   1 
ATOM   1974 C CA  . LEU A 1 265 ? 123.859 98.473  125.546 1.00 76.32  ? 265 LEU A CA  1 
ATOM   1975 C C   . LEU A 1 265 ? 123.971 99.987  125.491 1.00 82.19  ? 265 LEU A C   1 
ATOM   1976 O O   . LEU A 1 265 ? 125.037 100.494 125.132 1.00 84.34  ? 265 LEU A O   1 
ATOM   1977 C CB  . LEU A 1 265 ? 123.887 97.919  124.122 1.00 74.55  ? 265 LEU A CB  1 
ATOM   1978 C CG  . LEU A 1 265 ? 124.584 96.581  123.878 1.00 82.35  ? 265 LEU A CG  1 
ATOM   1979 C CD1 . LEU A 1 265 ? 126.086 96.785  123.867 1.00 85.71  ? 265 LEU A CD1 1 
ATOM   1980 C CD2 . LEU A 1 265 ? 124.202 95.541  124.914 1.00 85.61  ? 265 LEU A CD2 1 
ATOM   1981 N N   . GLN A 1 266 ? 122.905 100.717 125.820 1.00 83.40  ? 266 GLN A N   1 
ATOM   1982 C CA  . GLN A 1 266 ? 122.991 102.171 125.827 1.00 80.01  ? 266 GLN A CA  1 
ATOM   1983 C C   . GLN A 1 266 ? 123.993 102.679 126.851 1.00 81.50  ? 266 GLN A C   1 
ATOM   1984 O O   . GLN A 1 266 ? 124.721 103.637 126.577 1.00 83.84  ? 266 GLN A O   1 
ATOM   1985 C CB  . GLN A 1 266 ? 121.622 102.782 126.087 1.00 70.37  ? 266 GLN A CB  1 
ATOM   1986 C CG  . GLN A 1 266 ? 121.679 104.271 126.271 1.00 72.91  ? 266 GLN A CG  1 
ATOM   1987 C CD  . GLN A 1 266 ? 120.556 104.971 125.574 1.00 80.26  ? 266 GLN A CD  1 
ATOM   1988 O OE1 . GLN A 1 266 ? 120.650 105.297 124.394 1.00 83.05  ? 266 GLN A OE1 1 
ATOM   1989 N NE2 . GLN A 1 266 ? 119.465 105.178 126.287 1.00 85.66  ? 266 GLN A NE2 1 
ATOM   1990 N N   . PHE A 1 267 ? 124.051 102.064 128.030 1.00 76.96  ? 267 PHE A N   1 
ATOM   1991 C CA  . PHE A 1 267 ? 125.013 102.507 129.029 1.00 73.47  ? 267 PHE A CA  1 
ATOM   1992 C C   . PHE A 1 267 ? 126.451 102.303 128.574 1.00 76.57  ? 267 PHE A C   1 
ATOM   1993 O O   . PHE A 1 267 ? 127.353 102.954 129.106 1.00 81.45  ? 267 PHE A O   1 
ATOM   1994 C CB  . PHE A 1 267 ? 124.753 101.789 130.348 1.00 77.13  ? 267 PHE A CB  1 
ATOM   1995 C CG  . PHE A 1 267 ? 123.445 102.156 130.979 1.00 79.17  ? 267 PHE A CG  1 
ATOM   1996 C CD1 . PHE A 1 267 ? 122.904 103.411 130.788 1.00 76.29  ? 267 PHE A CD1 1 
ATOM   1997 C CD2 . PHE A 1 267 ? 122.750 101.247 131.753 1.00 81.49  ? 267 PHE A CD2 1 
ATOM   1998 C CE1 . PHE A 1 267 ? 121.701 103.760 131.359 1.00 74.94  ? 267 PHE A CE1 1 
ATOM   1999 C CE2 . PHE A 1 267 ? 121.545 101.591 132.326 1.00 82.50  ? 267 PHE A CE2 1 
ATOM   2000 C CZ  . PHE A 1 267 ? 121.022 102.852 132.127 1.00 77.82  ? 267 PHE A CZ  1 
ATOM   2001 N N   . THR A 1 268 ? 126.687 101.425 127.606 1.00 66.00  ? 268 THR A N   1 
ATOM   2002 C CA  . THR A 1 268 ? 128.007 101.318 127.013 1.00 69.20  ? 268 THR A CA  1 
ATOM   2003 C C   . THR A 1 268 ? 128.273 102.525 126.112 1.00 72.86  ? 268 THR A C   1 
ATOM   2004 O O   . THR A 1 268 ? 127.337 103.158 125.622 1.00 75.89  ? 268 THR A O   1 
ATOM   2005 C CB  . THR A 1 268 ? 128.128 100.031 126.206 1.00 71.23  ? 268 THR A CB  1 
ATOM   2006 O OG1 . THR A 1 268 ? 127.286 100.112 125.052 1.00 77.54  ? 268 THR A OG1 1 
ATOM   2007 C CG2 . THR A 1 268 ? 127.710 98.845  127.046 1.00 73.64  ? 268 THR A CG2 1 
ATOM   2008 N N   . PRO A 1 269 ? 129.540 102.872 125.890 1.00 66.77  ? 269 PRO A N   1 
ATOM   2009 C CA  . PRO A 1 269 ? 129.845 104.013 125.023 1.00 62.26  ? 269 PRO A CA  1 
ATOM   2010 C C   . PRO A 1 269 ? 129.402 103.776 123.589 1.00 66.64  ? 269 PRO A C   1 
ATOM   2011 O O   . PRO A 1 269 ? 129.392 102.647 123.096 1.00 71.68  ? 269 PRO A O   1 
ATOM   2012 C CB  . PRO A 1 269 ? 131.368 104.134 125.119 1.00 66.28  ? 269 PRO A CB  1 
ATOM   2013 C CG  . PRO A 1 269 ? 131.824 102.813 125.608 1.00 70.62  ? 269 PRO A CG  1 
ATOM   2014 C CD  . PRO A 1 269 ? 130.753 102.329 126.515 1.00 71.09  ? 269 PRO A CD  1 
ATOM   2015 N N   . ALA A 1 270 ? 129.034 104.868 122.917 1.00 66.23  ? 270 ALA A N   1 
ATOM   2016 C CA  . ALA A 1 270 ? 128.621 104.818 121.522 1.00 67.61  ? 270 ALA A CA  1 
ATOM   2017 C C   . ALA A 1 270 ? 129.786 104.876 120.547 1.00 70.66  ? 270 ALA A C   1 
ATOM   2018 O O   . ALA A 1 270 ? 129.611 104.534 119.373 1.00 69.89  ? 270 ALA A O   1 
ATOM   2019 C CB  . ALA A 1 270 ? 127.663 105.967 121.211 1.00 63.96  ? 270 ALA A CB  1 
ATOM   2020 N N   . SER A 1 271 ? 130.959 105.306 120.998 1.00 76.28  ? 271 SER A N   1 
ATOM   2021 C CA  . SER A 1 271 ? 132.140 105.360 120.152 1.00 70.43  ? 271 SER A CA  1 
ATOM   2022 C C   . SER A 1 271 ? 133.361 105.420 121.053 1.00 74.94  ? 271 SER A C   1 
ATOM   2023 O O   . SER A 1 271 ? 133.269 105.786 122.226 1.00 74.62  ? 271 SER A O   1 
ATOM   2024 C CB  . SER A 1 271 ? 132.098 106.562 119.205 1.00 68.80  ? 271 SER A CB  1 
ATOM   2025 O OG  . SER A 1 271 ? 132.080 107.775 119.933 1.00 76.98  ? 271 SER A OG  1 
ATOM   2026 N N   . TRP A 1 272 ? 134.509 105.051 120.494 1.00 77.34  ? 272 TRP A N   1 
ATOM   2027 C CA  . TRP A 1 272 ? 135.762 105.051 121.237 1.00 76.76  ? 272 TRP A CA  1 
ATOM   2028 C C   . TRP A 1 272 ? 136.823 105.778 120.431 1.00 79.25  ? 272 TRP A C   1 
ATOM   2029 O O   . TRP A 1 272 ? 137.184 105.339 119.336 1.00 83.63  ? 272 TRP A O   1 
ATOM   2030 C CB  . TRP A 1 272 ? 136.207 103.627 121.570 1.00 73.71  ? 272 TRP A CB  1 
ATOM   2031 C CG  . TRP A 1 272 ? 136.984 103.560 122.835 1.00 78.77  ? 272 TRP A CG  1 
ATOM   2032 C CD1 . TRP A 1 272 ? 138.333 103.442 122.963 1.00 79.46  ? 272 TRP A CD1 1 
ATOM   2033 C CD2 . TRP A 1 272 ? 136.465 103.688 124.161 1.00 80.91  ? 272 TRP A CD2 1 
ATOM   2034 N NE1 . TRP A 1 272 ? 138.685 103.446 124.290 1.00 75.12  ? 272 TRP A NE1 1 
ATOM   2035 C CE2 . TRP A 1 272 ? 137.554 103.601 125.045 1.00 80.77  ? 272 TRP A CE2 1 
ATOM   2036 C CE3 . TRP A 1 272 ? 135.182 103.855 124.687 1.00 76.92  ? 272 TRP A CE3 1 
ATOM   2037 C CZ2 . TRP A 1 272 ? 137.399 103.671 126.424 1.00 84.29  ? 272 TRP A CZ2 1 
ATOM   2038 C CZ3 . TRP A 1 272 ? 135.033 103.924 126.055 1.00 73.60  ? 272 TRP A CZ3 1 
ATOM   2039 C CH2 . TRP A 1 272 ? 136.131 103.831 126.908 1.00 77.77  ? 272 TRP A CH2 1 
ATOM   2040 N N   . THR A 1 273 ? 137.319 106.884 120.976 1.00 75.15  ? 273 THR A N   1 
ATOM   2041 C CA  . THR A 1 273 ? 138.332 107.660 120.282 1.00 76.76  ? 273 THR A CA  1 
ATOM   2042 C C   . THR A 1 273 ? 139.673 106.939 120.313 1.00 76.64  ? 273 THR A C   1 
ATOM   2043 O O   . THR A 1 273 ? 139.942 106.121 121.196 1.00 79.77  ? 273 THR A O   1 
ATOM   2044 C CB  . THR A 1 273 ? 138.457 109.051 120.897 1.00 82.08  ? 273 THR A CB  1 
ATOM   2045 O OG1 . THR A 1 273 ? 139.259 109.880 120.046 1.00 84.39  ? 273 THR A OG1 1 
ATOM   2046 C CG2 . THR A 1 273 ? 139.085 108.978 122.266 1.00 77.09  ? 273 THR A CG2 1 
ATOM   2047 N N   . TYR A 1 274 ? 140.505 107.240 119.324 1.00 82.40  ? 274 TYR A N   1 
ATOM   2048 C CA  . TYR A 1 274 ? 141.772 106.553 119.124 1.00 78.35  ? 274 TYR A CA  1 
ATOM   2049 C C   . TYR A 1 274 ? 142.859 107.284 119.902 1.00 80.71  ? 274 TYR A C   1 
ATOM   2050 O O   . TYR A 1 274 ? 143.379 108.302 119.437 1.00 88.20  ? 274 TYR A O   1 
ATOM   2051 C CB  . TYR A 1 274 ? 142.084 106.531 117.632 1.00 83.98  ? 274 TYR A CB  1 
ATOM   2052 C CG  . TYR A 1 274 ? 143.317 105.777 117.223 1.00 88.69  ? 274 TYR A CG  1 
ATOM   2053 C CD1 . TYR A 1 274 ? 144.160 106.281 116.240 1.00 89.21  ? 274 TYR A CD1 1 
ATOM   2054 C CD2 . TYR A 1 274 ? 143.605 104.535 117.759 1.00 86.09  ? 274 TYR A CD2 1 
ATOM   2055 C CE1 . TYR A 1 274 ? 145.282 105.592 115.839 1.00 90.20  ? 274 TYR A CE1 1 
ATOM   2056 C CE2 . TYR A 1 274 ? 144.717 103.832 117.356 1.00 85.69  ? 274 TYR A CE2 1 
ATOM   2057 C CZ  . TYR A 1 274 ? 145.560 104.367 116.402 1.00 88.86  ? 274 TYR A CZ  1 
ATOM   2058 O OH  . TYR A 1 274 ? 146.677 103.670 116.004 1.00 85.70  ? 274 TYR A OH  1 
ATOM   2059 N N   . VAL A 1 275 ? 143.215 106.768 121.074 1.00 72.65  ? 275 VAL A N   1 
ATOM   2060 C CA  . VAL A 1 275 ? 144.044 107.498 122.028 1.00 70.00  ? 275 VAL A CA  1 
ATOM   2061 C C   . VAL A 1 275 ? 145.479 106.993 121.927 1.00 73.36  ? 275 VAL A C   1 
ATOM   2062 O O   . VAL A 1 275 ? 145.797 105.907 122.424 1.00 80.84  ? 275 VAL A O   1 
ATOM   2063 C CB  . VAL A 1 275 ? 143.508 107.345 123.461 1.00 71.34  ? 275 VAL A CB  1 
ATOM   2064 C CG1 . VAL A 1 275 ? 144.556 107.757 124.480 1.00 72.82  ? 275 VAL A CG1 1 
ATOM   2065 C CG2 . VAL A 1 275 ? 142.248 108.152 123.644 1.00 73.99  ? 275 VAL A CG2 1 
ATOM   2066 N N   . ARG A 1 276 ? 146.341 107.779 121.279 1.00 74.64  ? 276 ARG A N   1 
ATOM   2067 C CA  . ARG A 1 276 ? 147.796 107.599 121.294 1.00 75.73  ? 276 ARG A CA  1 
ATOM   2068 C C   . ARG A 1 276 ? 148.419 108.873 121.858 1.00 79.27  ? 276 ARG A C   1 
ATOM   2069 O O   . ARG A 1 276 ? 148.395 109.921 121.207 1.00 79.15  ? 276 ARG A O   1 
ATOM   2070 C CB  . ARG A 1 276 ? 148.374 107.287 119.909 1.00 76.24  ? 276 ARG A CB  1 
ATOM   2071 C CG  . ARG A 1 276 ? 148.275 105.845 119.380 1.00 77.56  ? 276 ARG A CG  1 
ATOM   2072 C CD  . ARG A 1 276 ? 147.129 105.032 119.920 1.00 83.16  ? 276 ARG A CD  1 
ATOM   2073 N NE  . ARG A 1 276 ? 147.028 103.721 119.291 1.00 84.46  ? 276 ARG A NE  1 
ATOM   2074 C CZ  . ARG A 1 276 ? 146.471 102.661 119.859 1.00 82.82  ? 276 ARG A CZ  1 
ATOM   2075 N NH1 . ARG A 1 276 ? 145.954 102.724 121.073 1.00 75.82  ? 276 ARG A NH1 1 
ATOM   2076 N NH2 . ARG A 1 276 ? 146.432 101.512 119.193 1.00 82.50  ? 276 ARG A NH2 1 
ATOM   2077 N N   . TRP A 1 277 ? 148.983 108.775 123.063 1.00 68.88  ? 277 TRP A N   1 
ATOM   2078 C CA  . TRP A 1 277 ? 149.533 109.952 123.727 1.00 63.47  ? 277 TRP A CA  1 
ATOM   2079 C C   . TRP A 1 277 ? 150.800 110.442 123.042 1.00 68.99  ? 277 TRP A C   1 
ATOM   2080 O O   . TRP A 1 277 ? 150.995 111.651 122.875 1.00 69.83  ? 277 TRP A O   1 
ATOM   2081 C CB  . TRP A 1 277 ? 149.808 109.631 125.193 1.00 61.46  ? 277 TRP A CB  1 
ATOM   2082 C CG  . TRP A 1 277 ? 148.560 109.444 125.979 1.00 62.74  ? 277 TRP A CG  1 
ATOM   2083 C CD1 . TRP A 1 277 ? 147.927 108.268 126.231 1.00 67.82  ? 277 TRP A CD1 1 
ATOM   2084 C CD2 . TRP A 1 277 ? 147.784 110.462 126.615 1.00 60.99  ? 277 TRP A CD2 1 
ATOM   2085 N NE1 . TRP A 1 277 ? 146.802 108.487 126.982 1.00 67.52  ? 277 TRP A NE1 1 
ATOM   2086 C CE2 . TRP A 1 277 ? 146.694 109.828 127.233 1.00 62.85  ? 277 TRP A CE2 1 
ATOM   2087 C CE3 . TRP A 1 277 ? 147.907 111.847 126.723 1.00 62.15  ? 277 TRP A CE3 1 
ATOM   2088 C CZ2 . TRP A 1 277 ? 145.735 110.529 127.946 1.00 59.77  ? 277 TRP A CZ2 1 
ATOM   2089 C CZ3 . TRP A 1 277 ? 146.955 112.539 127.433 1.00 62.35  ? 277 TRP A CZ3 1 
ATOM   2090 C CH2 . TRP A 1 277 ? 145.882 111.881 128.034 1.00 62.74  ? 277 TRP A CH2 1 
ATOM   2091 N N   . PHE A 1 278 ? 151.670 109.523 122.640 1.00 85.86  ? 278 PHE A N   1 
ATOM   2092 C CA  . PHE A 1 278 ? 152.995 109.852 122.133 1.00 82.65  ? 278 PHE A CA  1 
ATOM   2093 C C   . PHE A 1 278 ? 153.017 109.732 120.618 1.00 82.13  ? 278 PHE A C   1 
ATOM   2094 O O   . PHE A 1 278 ? 152.924 108.626 120.078 1.00 81.74  ? 278 PHE A O   1 
ATOM   2095 C CB  . PHE A 1 278 ? 154.049 108.934 122.746 1.00 80.90  ? 278 PHE A CB  1 
ATOM   2096 C CG  . PHE A 1 278 ? 154.228 109.121 124.217 1.00 81.59  ? 278 PHE A CG  1 
ATOM   2097 C CD1 . PHE A 1 278 ? 154.696 110.319 124.716 1.00 77.68  ? 278 PHE A CD1 1 
ATOM   2098 C CD2 . PHE A 1 278 ? 153.927 108.103 125.100 1.00 84.57  ? 278 PHE A CD2 1 
ATOM   2099 C CE1 . PHE A 1 278 ? 154.866 110.498 126.065 1.00 85.38  ? 278 PHE A CE1 1 
ATOM   2100 C CE2 . PHE A 1 278 ? 154.091 108.276 126.453 1.00 83.76  ? 278 PHE A CE2 1 
ATOM   2101 C CZ  . PHE A 1 278 ? 154.562 109.476 126.937 1.00 88.95  ? 278 PHE A CZ  1 
ATOM   2102 N N   . ASP A 1 279 ? 153.145 110.862 119.944 1.00 95.98  ? 279 ASP A N   1 
ATOM   2103 C CA  . ASP A 1 279 ? 153.391 110.848 118.515 1.00 101.20 ? 279 ASP A CA  1 
ATOM   2104 C C   . ASP A 1 279 ? 154.836 110.437 118.241 1.00 102.71 ? 279 ASP A C   1 
ATOM   2105 O O   . ASP A 1 279 ? 155.725 110.695 119.057 1.00 100.28 ? 279 ASP A O   1 
ATOM   2106 C CB  . ASP A 1 279 ? 153.122 112.223 117.915 1.00 99.04  ? 279 ASP A CB  1 
ATOM   2107 C CG  . ASP A 1 279 ? 151.828 112.273 117.136 1.00 99.09  ? 279 ASP A CG  1 
ATOM   2108 O OD1 . ASP A 1 279 ? 151.485 111.262 116.489 1.00 98.97  ? 279 ASP A OD1 1 
ATOM   2109 O OD2 . ASP A 1 279 ? 151.153 113.322 117.169 1.00 98.64  ? 279 ASP A OD2 1 
ATOM   2110 N N   . PRO A 1 280 ? 155.094 109.780 117.109 1.00 112.35 ? 280 PRO A N   1 
ATOM   2111 C CA  . PRO A 1 280 ? 156.483 109.419 116.781 1.00 110.54 ? 280 PRO A CA  1 
ATOM   2112 C C   . PRO A 1 280 ? 157.405 110.619 116.675 1.00 111.52 ? 280 PRO A C   1 
ATOM   2113 O O   . PRO A 1 280 ? 158.590 110.513 117.014 1.00 112.11 ? 280 PRO A O   1 
ATOM   2114 C CB  . PRO A 1 280 ? 156.346 108.687 115.439 1.00 110.80 ? 280 PRO A CB  1 
ATOM   2115 C CG  . PRO A 1 280 ? 154.938 108.189 115.425 1.00 111.92 ? 280 PRO A CG  1 
ATOM   2116 C CD  . PRO A 1 280 ? 154.136 109.240 116.131 1.00 111.66 ? 280 PRO A CD  1 
ATOM   2117 N N   . LYS A 1 281 ? 156.897 111.759 116.217 1.00 109.35 ? 281 LYS A N   1 
ATOM   2118 C CA  . LYS A 1 281 ? 157.661 112.998 116.123 1.00 110.88 ? 281 LYS A CA  1 
ATOM   2119 C C   . LYS A 1 281 ? 157.170 114.018 117.145 1.00 110.15 ? 281 LYS A C   1 
ATOM   2120 O O   . LYS A 1 281 ? 157.046 115.207 116.849 1.00 111.99 ? 281 LYS A O   1 
ATOM   2121 C CB  . LYS A 1 281 ? 157.585 113.580 114.713 1.00 110.62 ? 281 LYS A CB  1 
ATOM   2122 C CG  . LYS A 1 281 ? 158.104 112.665 113.611 1.00 109.74 ? 281 LYS A CG  1 
ATOM   2123 C CD  . LYS A 1 281 ? 159.326 111.875 114.049 1.00 109.50 ? 281 LYS A CD  1 
ATOM   2124 C CE  . LYS A 1 281 ? 159.753 110.890 112.971 1.00 108.84 ? 281 LYS A CE  1 
ATOM   2125 N NZ  . LYS A 1 281 ? 158.867 109.695 112.925 1.00 104.70 ? 281 LYS A NZ  1 
ATOM   2126 N N   . SER A 1 282 ? 156.873 113.552 118.357 1.00 100.86 ? 282 SER A N   1 
ATOM   2127 C CA  . SER A 1 282 ? 156.250 114.403 119.361 1.00 99.58  ? 282 SER A CA  1 
ATOM   2128 C C   . SER A 1 282 ? 157.149 115.578 119.721 1.00 98.53  ? 282 SER A C   1 
ATOM   2129 O O   . SER A 1 282 ? 158.357 115.423 119.915 1.00 99.75  ? 282 SER A O   1 
ATOM   2130 C CB  . SER A 1 282 ? 155.934 113.592 120.615 1.00 99.32  ? 282 SER A CB  1 
ATOM   2131 O OG  . SER A 1 282 ? 156.915 113.808 121.610 1.00 102.78 ? 282 SER A OG  1 
ATOM   2132 N N   . SER A 1 283 ? 156.545 116.759 119.808 1.00 91.74  ? 283 SER A N   1 
ATOM   2133 C CA  . SER A 1 283 ? 157.266 117.968 120.162 1.00 94.02  ? 283 SER A CA  1 
ATOM   2134 C C   . SER A 1 283 ? 157.479 118.039 121.671 1.00 92.13  ? 283 SER A C   1 
ATOM   2135 O O   . SER A 1 283 ? 156.971 117.219 122.437 1.00 94.22  ? 283 SER A O   1 
ATOM   2136 C CB  . SER A 1 283 ? 156.512 119.200 119.668 1.00 93.47  ? 283 SER A CB  1 
ATOM   2137 O OG  . SER A 1 283 ? 155.152 119.152 120.058 1.00 90.92  ? 283 SER A OG  1 
ATOM   2138 N N   . PHE A 1 284 ? 158.254 119.036 122.098 1.00 93.44  ? 284 PHE A N   1 
ATOM   2139 C CA  . PHE A 1 284 ? 158.487 119.216 123.527 1.00 91.60  ? 284 PHE A CA  1 
ATOM   2140 C C   . PHE A 1 284 ? 157.200 119.559 124.263 1.00 90.77  ? 284 PHE A C   1 
ATOM   2141 O O   . PHE A 1 284 ? 157.032 119.180 125.427 1.00 96.25  ? 284 PHE A O   1 
ATOM   2142 C CB  . PHE A 1 284 ? 159.536 120.303 123.759 1.00 93.69  ? 284 PHE A CB  1 
ATOM   2143 C CG  . PHE A 1 284 ? 160.949 119.824 123.599 1.00 98.92  ? 284 PHE A CG  1 
ATOM   2144 C CD1 . PHE A 1 284 ? 161.234 118.470 123.552 1.00 96.05  ? 284 PHE A CD1 1 
ATOM   2145 C CD2 . PHE A 1 284 ? 161.993 120.726 123.489 1.00 98.34  ? 284 PHE A CD2 1 
ATOM   2146 C CE1 . PHE A 1 284 ? 162.534 118.026 123.402 1.00 95.78  ? 284 PHE A CE1 1 
ATOM   2147 C CE2 . PHE A 1 284 ? 163.295 120.288 123.340 1.00 96.18  ? 284 PHE A CE2 1 
ATOM   2148 C CZ  . PHE A 1 284 ? 163.565 118.937 123.296 1.00 95.41  ? 284 PHE A CZ  1 
ATOM   2149 N N   . GLN A 1 285 ? 156.286 120.274 123.607 1.00 84.22  ? 285 GLN A N   1 
ATOM   2150 C CA  . GLN A 1 285 ? 155.031 120.638 124.254 1.00 83.19  ? 285 GLN A CA  1 
ATOM   2151 C C   . GLN A 1 285 ? 154.203 119.404 124.591 1.00 84.63  ? 285 GLN A C   1 
ATOM   2152 O O   . GLN A 1 285 ? 153.612 119.324 125.671 1.00 92.59  ? 285 GLN A O   1 
ATOM   2153 C CB  . GLN A 1 285 ? 154.241 121.590 123.361 1.00 88.67  ? 285 GLN A CB  1 
ATOM   2154 C CG  . GLN A 1 285 ? 155.076 122.716 122.779 1.00 90.98  ? 285 GLN A CG  1 
ATOM   2155 C CD  . GLN A 1 285 ? 155.085 123.950 123.655 1.00 93.55  ? 285 GLN A CD  1 
ATOM   2156 O OE1 . GLN A 1 285 ? 155.054 123.856 124.881 1.00 93.76  ? 285 GLN A OE1 1 
ATOM   2157 N NE2 . GLN A 1 285 ? 155.130 125.120 123.027 1.00 90.05  ? 285 GLN A NE2 1 
ATOM   2158 N N   . ARG A 1 286 ? 154.150 118.429 123.684 1.00 78.69  ? 286 ARG A N   1 
ATOM   2159 C CA  . ARG A 1 286 ? 153.388 117.214 123.955 1.00 78.21  ? 286 ARG A CA  1 
ATOM   2160 C C   . ARG A 1 286 ? 154.008 116.409 125.092 1.00 77.96  ? 286 ARG A C   1 
ATOM   2161 O O   . ARG A 1 286 ? 153.291 115.866 125.943 1.00 83.03  ? 286 ARG A O   1 
ATOM   2162 C CB  . ARG A 1 286 ? 153.288 116.372 122.688 1.00 77.78  ? 286 ARG A CB  1 
ATOM   2163 C CG  . ARG A 1 286 ? 152.203 115.320 122.714 1.00 75.30  ? 286 ARG A CG  1 
ATOM   2164 C CD  . ARG A 1 286 ? 151.448 115.333 121.401 1.00 78.76  ? 286 ARG A CD  1 
ATOM   2165 N NE  . ARG A 1 286 ? 150.628 114.146 121.212 1.00 78.83  ? 286 ARG A NE  1 
ATOM   2166 C CZ  . ARG A 1 286 ? 149.878 113.926 120.142 1.00 83.47  ? 286 ARG A CZ  1 
ATOM   2167 N NH1 . ARG A 1 286 ? 149.811 114.802 119.154 1.00 81.87  ? 286 ARG A NH1 1 
ATOM   2168 N NH2 . ARG A 1 286 ? 149.183 112.797 120.058 1.00 85.15  ? 286 ARG A NH2 1 
ATOM   2169 N N   . VAL A 1 287 ? 155.338 116.316 125.123 1.00 70.21  ? 287 VAL A N   1 
ATOM   2170 C CA  . VAL A 1 287 ? 156.003 115.608 126.212 1.00 65.47  ? 287 VAL A CA  1 
ATOM   2171 C C   . VAL A 1 287 ? 155.727 116.300 127.537 1.00 65.71  ? 287 VAL A C   1 
ATOM   2172 O O   . VAL A 1 287 ? 155.456 115.646 128.550 1.00 77.38  ? 287 VAL A O   1 
ATOM   2173 C CB  . VAL A 1 287 ? 157.512 115.492 125.937 1.00 70.84  ? 287 VAL A CB  1 
ATOM   2174 C CG1 . VAL A 1 287 ? 158.169 114.613 126.982 1.00 73.70  ? 287 VAL A CG1 1 
ATOM   2175 C CG2 . VAL A 1 287 ? 157.753 114.935 124.552 1.00 70.84  ? 287 VAL A CG2 1 
ATOM   2176 N N   . ALA A 1 288 ? 155.788 117.631 127.553 1.00 61.78  ? 288 ALA A N   1 
ATOM   2177 C CA  . ALA A 1 288 ? 155.493 118.365 128.778 1.00 67.05  ? 288 ALA A CA  1 
ATOM   2178 C C   . ALA A 1 288 ? 154.041 118.179 129.198 1.00 69.81  ? 288 ALA A C   1 
ATOM   2179 O O   . ALA A 1 288 ? 153.742 118.099 130.394 1.00 78.30  ? 288 ALA A O   1 
ATOM   2180 C CB  . ALA A 1 288 ? 155.816 119.846 128.595 1.00 69.23  ? 288 ALA A CB  1 
ATOM   2181 N N   . GLY A 1 289 ? 153.126 118.109 128.234 1.00 58.96  ? 289 GLY A N   1 
ATOM   2182 C CA  . GLY A 1 289 ? 151.733 117.870 128.573 1.00 60.27  ? 289 GLY A CA  1 
ATOM   2183 C C   . GLY A 1 289 ? 151.517 116.511 129.208 1.00 67.09  ? 289 GLY A C   1 
ATOM   2184 O O   . GLY A 1 289 ? 150.803 116.381 130.205 1.00 75.84  ? 289 GLY A O   1 
ATOM   2185 N N   . VAL A 1 290 ? 152.138 115.476 128.642 1.00 62.03  ? 290 VAL A N   1 
ATOM   2186 C CA  . VAL A 1 290 ? 152.014 114.145 129.231 1.00 56.58  ? 290 VAL A CA  1 
ATOM   2187 C C   . VAL A 1 290 ? 152.667 114.108 130.608 1.00 66.52  ? 290 VAL A C   1 
ATOM   2188 O O   . VAL A 1 290 ? 152.172 113.445 131.531 1.00 79.90  ? 290 VAL A O   1 
ATOM   2189 C CB  . VAL A 1 290 ? 152.602 113.081 128.290 1.00 55.38  ? 290 VAL A CB  1 
ATOM   2190 C CG1 . VAL A 1 290 ? 152.427 111.706 128.882 1.00 60.14  ? 290 VAL A CG1 1 
ATOM   2191 C CG2 . VAL A 1 290 ? 151.922 113.143 126.945 1.00 62.97  ? 290 VAL A CG2 1 
ATOM   2192 N N   . TYR A 1 291 ? 153.785 114.820 130.775 1.00 62.34  ? 291 TYR A N   1 
ATOM   2193 C CA  . TYR A 1 291 ? 154.430 114.880 132.082 1.00 57.06  ? 291 TYR A CA  1 
ATOM   2194 C C   . TYR A 1 291 ? 153.527 115.533 133.115 1.00 53.03  ? 291 TYR A C   1 
ATOM   2195 O O   . TYR A 1 291 ? 153.418 115.052 134.248 1.00 61.68  ? 291 TYR A O   1 
ATOM   2196 C CB  . TYR A 1 291 ? 155.749 115.637 131.988 1.00 56.29  ? 291 TYR A CB  1 
ATOM   2197 C CG  . TYR A 1 291 ? 156.580 115.521 133.234 1.00 54.75  ? 291 TYR A CG  1 
ATOM   2198 C CD1 . TYR A 1 291 ? 156.860 114.285 133.786 1.00 60.68  ? 291 TYR A CD1 1 
ATOM   2199 C CD2 . TYR A 1 291 ? 157.074 116.645 133.867 1.00 62.16  ? 291 TYR A CD2 1 
ATOM   2200 C CE1 . TYR A 1 291 ? 157.616 114.170 134.926 1.00 58.84  ? 291 TYR A CE1 1 
ATOM   2201 C CE2 . TYR A 1 291 ? 157.830 116.540 135.009 1.00 65.72  ? 291 TYR A CE2 1 
ATOM   2202 C CZ  . TYR A 1 291 ? 158.098 115.299 135.533 1.00 64.72  ? 291 TYR A CZ  1 
ATOM   2203 O OH  . TYR A 1 291 ? 158.851 115.189 136.675 1.00 74.09  ? 291 TYR A OH  1 
ATOM   2204 N N   . LEU A 1 292 ? 152.875 116.633 132.745 1.00 51.86  ? 292 LEU A N   1 
ATOM   2205 C CA  . LEU A 1 292 ? 151.938 117.272 133.659 1.00 54.87  ? 292 LEU A CA  1 
ATOM   2206 C C   . LEU A 1 292 ? 150.768 116.351 133.971 1.00 55.90  ? 292 LEU A C   1 
ATOM   2207 O O   . LEU A 1 292 ? 150.273 116.328 135.101 1.00 64.60  ? 292 LEU A O   1 
ATOM   2208 C CB  . LEU A 1 292 ? 151.442 118.590 133.072 1.00 58.56  ? 292 LEU A CB  1 
ATOM   2209 C CG  . LEU A 1 292 ? 150.454 119.343 133.955 1.00 57.70  ? 292 LEU A CG  1 
ATOM   2210 C CD1 . LEU A 1 292 ? 151.150 119.831 135.202 1.00 62.56  ? 292 LEU A CD1 1 
ATOM   2211 C CD2 . LEU A 1 292 ? 149.839 120.497 133.196 1.00 59.59  ? 292 LEU A CD2 1 
ATOM   2212 N N   . PHE A 1 293 ? 150.309 115.591 132.978 1.00 45.94  ? 293 PHE A N   1 
ATOM   2213 C CA  . PHE A 1 293 ? 149.246 114.620 133.217 1.00 44.02  ? 293 PHE A CA  1 
ATOM   2214 C C   . PHE A 1 293 ? 149.649 113.620 134.290 1.00 52.85  ? 293 PHE A C   1 
ATOM   2215 O O   . PHE A 1 293 ? 148.906 113.381 135.251 1.00 67.33  ? 293 PHE A O   1 
ATOM   2216 C CB  . PHE A 1 293 ? 148.911 113.900 131.916 1.00 50.79  ? 293 PHE A CB  1 
ATOM   2217 C CG  . PHE A 1 293 ? 147.745 112.972 132.017 1.00 52.65  ? 293 PHE A CG  1 
ATOM   2218 C CD1 . PHE A 1 293 ? 146.469 113.465 132.184 1.00 54.48  ? 293 PHE A CD1 1 
ATOM   2219 C CD2 . PHE A 1 293 ? 147.922 111.609 131.926 1.00 49.09  ? 293 PHE A CD2 1 
ATOM   2220 C CE1 . PHE A 1 293 ? 145.398 112.619 132.263 1.00 49.31  ? 293 PHE A CE1 1 
ATOM   2221 C CE2 . PHE A 1 293 ? 146.850 110.762 132.008 1.00 49.67  ? 293 PHE A CE2 1 
ATOM   2222 C CZ  . PHE A 1 293 ? 145.589 111.271 132.179 1.00 50.23  ? 293 PHE A CZ  1 
ATOM   2223 N N   . MET A 1 294 ? 150.835 113.030 134.145 1.00 52.88  ? 294 MET A N   1 
ATOM   2224 C CA  . MET A 1 294 ? 151.296 112.050 135.125 1.00 50.39  ? 294 MET A CA  1 
ATOM   2225 C C   . MET A 1 294 ? 151.478 112.685 136.500 1.00 56.48  ? 294 MET A C   1 
ATOM   2226 O O   . MET A 1 294 ? 151.157 112.071 137.528 1.00 60.43  ? 294 MET A O   1 
ATOM   2227 C CB  . MET A 1 294 ? 152.596 111.411 134.647 1.00 54.06  ? 294 MET A CB  1 
ATOM   2228 C CG  . MET A 1 294 ? 152.496 110.774 133.277 1.00 58.48  ? 294 MET A CG  1 
ATOM   2229 S SD  . MET A 1 294 ? 153.913 109.735 132.897 1.00 64.95  ? 294 MET A SD  1 
ATOM   2230 C CE  . MET A 1 294 ? 153.599 108.355 133.985 1.00 63.33  ? 294 MET A CE  1 
ATOM   2231 N N   . ILE A 1 295 ? 151.995 113.914 136.538 1.00 58.21  ? 295 ILE A N   1 
ATOM   2232 C CA  . ILE A 1 295 ? 152.208 114.597 137.811 1.00 50.12  ? 295 ILE A CA  1 
ATOM   2233 C C   . ILE A 1 295 ? 150.881 114.834 138.519 1.00 53.37  ? 295 ILE A C   1 
ATOM   2234 O O   . ILE A 1 295 ? 150.755 114.607 139.726 1.00 63.41  ? 295 ILE A O   1 
ATOM   2235 C CB  . ILE A 1 295 ? 152.973 115.913 137.591 1.00 48.58  ? 295 ILE A CB  1 
ATOM   2236 C CG1 . ILE A 1 295 ? 154.429 115.620 137.258 1.00 53.83  ? 295 ILE A CG1 1 
ATOM   2237 C CG2 . ILE A 1 295 ? 152.888 116.785 138.817 1.00 53.21  ? 295 ILE A CG2 1 
ATOM   2238 C CD1 . ILE A 1 295 ? 155.177 114.992 138.383 1.00 54.18  ? 295 ILE A CD1 1 
ATOM   2239 N N   . ILE A 1 296 ? 149.868 115.289 137.781 1.00 52.76  ? 296 ILE A N   1 
ATOM   2240 C CA  . ILE A 1 296 ? 148.567 115.520 138.402 1.00 50.48  ? 296 ILE A CA  1 
ATOM   2241 C C   . ILE A 1 296 ? 147.941 114.206 138.848 1.00 56.29  ? 296 ILE A C   1 
ATOM   2242 O O   . ILE A 1 296 ? 147.243 114.160 139.868 1.00 69.64  ? 296 ILE A O   1 
ATOM   2243 C CB  . ILE A 1 296 ? 147.636 116.292 137.454 1.00 55.79  ? 296 ILE A CB  1 
ATOM   2244 C CG1 . ILE A 1 296 ? 148.274 117.614 137.047 1.00 56.57  ? 296 ILE A CG1 1 
ATOM   2245 C CG2 . ILE A 1 296 ? 146.310 116.572 138.131 1.00 61.50  ? 296 ILE A CG2 1 
ATOM   2246 C CD1 . ILE A 1 296 ? 148.755 118.423 138.205 1.00 60.40  ? 296 ILE A CD1 1 
ATOM   2247 N N   . TRP A 1 297 ? 148.167 113.121 138.108 1.00 53.83  ? 297 TRP A N   1 
ATOM   2248 C CA  . TRP A 1 297 ? 147.658 111.826 138.552 1.00 52.10  ? 297 TRP A CA  1 
ATOM   2249 C C   . TRP A 1 297 ? 148.260 111.428 139.893 1.00 61.64  ? 297 TRP A C   1 
ATOM   2250 O O   . TRP A 1 297 ? 147.541 111.037 140.829 1.00 72.73  ? 297 TRP A O   1 
ATOM   2251 C CB  . TRP A 1 297 ? 147.948 110.761 137.501 1.00 59.11  ? 297 TRP A CB  1 
ATOM   2252 C CG  . TRP A 1 297 ? 147.061 109.599 137.650 1.00 63.69  ? 297 TRP A CG  1 
ATOM   2253 C CD1 . TRP A 1 297 ? 147.266 108.513 138.437 1.00 68.28  ? 297 TRP A CD1 1 
ATOM   2254 C CD2 . TRP A 1 297 ? 145.792 109.414 137.031 1.00 73.08  ? 297 TRP A CD2 1 
ATOM   2255 N NE1 . TRP A 1 297 ? 146.212 107.645 138.332 1.00 67.99  ? 297 TRP A NE1 1 
ATOM   2256 C CE2 . TRP A 1 297 ? 145.290 108.180 137.473 1.00 71.39  ? 297 TRP A CE2 1 
ATOM   2257 C CE3 . TRP A 1 297 ? 145.033 110.168 136.134 1.00 74.04  ? 297 TRP A CE3 1 
ATOM   2258 C CZ2 . TRP A 1 297 ? 144.063 107.687 137.055 1.00 71.34  ? 297 TRP A CZ2 1 
ATOM   2259 C CZ3 . TRP A 1 297 ? 143.816 109.678 135.721 1.00 71.48  ? 297 TRP A CZ3 1 
ATOM   2260 C CH2 . TRP A 1 297 ? 143.343 108.447 136.177 1.00 74.34  ? 297 TRP A CH2 1 
ATOM   2261 N N   . GLN A 1 298 ? 149.587 111.522 140.007 1.00 56.92  ? 298 GLN A N   1 
ATOM   2262 C CA  . GLN A 1 298 ? 150.216 111.223 141.287 1.00 50.38  ? 298 GLN A CA  1 
ATOM   2263 C C   . GLN A 1 298 ? 149.741 112.176 142.370 1.00 59.99  ? 298 GLN A C   1 
ATOM   2264 O O   . GLN A 1 298 ? 149.627 111.783 143.533 1.00 71.38  ? 298 GLN A O   1 
ATOM   2265 C CB  . GLN A 1 298 ? 151.734 111.280 141.178 1.00 53.95  ? 298 GLN A CB  1 
ATOM   2266 C CG  . GLN A 1 298 ? 152.375 109.938 140.925 1.00 57.79  ? 298 GLN A CG  1 
ATOM   2267 C CD  . GLN A 1 298 ? 152.819 109.779 139.496 1.00 69.45  ? 298 GLN A CD  1 
ATOM   2268 O OE1 . GLN A 1 298 ? 152.641 108.721 138.896 1.00 77.71  ? 298 GLN A OE1 1 
ATOM   2269 N NE2 . GLN A 1 298 ? 153.403 110.829 138.937 1.00 65.04  ? 298 GLN A NE2 1 
ATOM   2270 N N   . LEU A 1 299 ? 149.457 113.426 142.010 1.00 56.47  ? 299 LEU A N   1 
ATOM   2271 C CA  . LEU A 1 299 ? 148.940 114.373 142.989 1.00 46.79  ? 299 LEU A CA  1 
ATOM   2272 C C   . LEU A 1 299 ? 147.585 113.936 143.516 1.00 46.64  ? 299 LEU A C   1 
ATOM   2273 O O   . LEU A 1 299 ? 147.307 114.076 144.707 1.00 62.51  ? 299 LEU A O   1 
ATOM   2274 C CB  . LEU A 1 299 ? 148.844 115.767 142.379 1.00 55.50  ? 299 LEU A CB  1 
ATOM   2275 C CG  . LEU A 1 299 ? 148.755 116.914 143.377 1.00 52.32  ? 299 LEU A CG  1 
ATOM   2276 C CD1 . LEU A 1 299 ? 150.082 117.088 144.074 1.00 55.69  ? 299 LEU A CD1 1 
ATOM   2277 C CD2 . LEU A 1 299 ? 148.353 118.185 142.671 1.00 54.16  ? 299 LEU A CD2 1 
ATOM   2278 N N   . THR A 1 300 ? 146.718 113.423 142.645 1.00 50.50  ? 300 THR A N   1 
ATOM   2279 C CA  . THR A 1 300 ? 145.416 112.948 143.111 1.00 53.89  ? 300 THR A CA  1 
ATOM   2280 C C   . THR A 1 300 ? 145.570 111.747 144.038 1.00 56.89  ? 300 THR A C   1 
ATOM   2281 O O   . THR A 1 300 ? 144.884 111.646 145.066 1.00 65.87  ? 300 THR A O   1 
ATOM   2282 C CB  . THR A 1 300 ? 144.515 112.599 141.929 1.00 59.30  ? 300 THR A CB  1 
ATOM   2283 O OG1 . THR A 1 300 ? 145.094 111.522 141.185 1.00 69.49  ? 300 THR A OG1 1 
ATOM   2284 C CG2 . THR A 1 300 ? 144.338 113.800 141.032 1.00 58.09  ? 300 THR A CG2 1 
ATOM   2285 N N   . GLU A 1 301 ? 146.469 110.823 143.693 1.00 58.09  ? 301 GLU A N   1 
ATOM   2286 C CA  . GLU A 1 301 ? 146.717 109.690 144.586 1.00 57.92  ? 301 GLU A CA  1 
ATOM   2287 C C   . GLU A 1 301 ? 147.237 110.163 145.941 1.00 58.92  ? 301 GLU A C   1 
ATOM   2288 O O   . GLU A 1 301 ? 146.808 109.680 147.000 1.00 61.95  ? 301 GLU A O   1 
ATOM   2289 C CB  . GLU A 1 301 ? 147.705 108.719 143.942 1.00 58.51  ? 301 GLU A CB  1 
ATOM   2290 C CG  . GLU A 1 301 ? 147.313 108.260 142.555 1.00 65.64  ? 301 GLU A CG  1 
ATOM   2291 C CD  . GLU A 1 301 ? 146.638 106.906 142.563 1.00 70.43  ? 301 GLU A CD  1 
ATOM   2292 O OE1 . GLU A 1 301 ? 146.612 106.248 141.503 1.00 63.77  ? 301 GLU A OE1 1 
ATOM   2293 O OE2 . GLU A 1 301 ? 146.136 106.499 143.631 1.00 73.72  ? 301 GLU A OE2 1 
ATOM   2294 N N   . LEU A 1 302 ? 148.160 111.124 145.920 1.00 59.03  ? 302 LEU A N   1 
ATOM   2295 C CA  . LEU A 1 302 ? 148.722 111.675 147.147 1.00 54.51  ? 302 LEU A CA  1 
ATOM   2296 C C   . LEU A 1 302 ? 147.650 112.376 147.972 1.00 52.96  ? 302 LEU A C   1 
ATOM   2297 O O   . LEU A 1 302 ? 147.640 112.287 149.203 1.00 59.13  ? 302 LEU A O   1 
ATOM   2298 C CB  . LEU A 1 302 ? 149.850 112.641 146.790 1.00 51.60  ? 302 LEU A CB  1 
ATOM   2299 C CG  . LEU A 1 302 ? 151.001 112.823 147.766 1.00 51.88  ? 302 LEU A CG  1 
ATOM   2300 C CD1 . LEU A 1 302 ? 151.867 111.584 147.764 1.00 57.88  ? 302 LEU A CD1 1 
ATOM   2301 C CD2 . LEU A 1 302 ? 151.810 114.033 147.374 1.00 58.29  ? 302 LEU A CD2 1 
ATOM   2302 N N   . ASN A 1 303 ? 146.747 113.093 147.303 1.00 48.58  ? 303 ASN A N   1 
ATOM   2303 C CA  . ASN A 1 303 ? 145.653 113.758 147.997 1.00 42.22  ? 303 ASN A CA  1 
ATOM   2304 C C   . ASN A 1 303 ? 144.758 112.752 148.695 1.00 56.75  ? 303 ASN A C   1 
ATOM   2305 O O   . ASN A 1 303 ? 144.366 112.960 149.845 1.00 67.39  ? 303 ASN A O   1 
ATOM   2306 C CB  . ASN A 1 303 ? 144.837 114.595 147.016 1.00 42.93  ? 303 ASN A CB  1 
ATOM   2307 C CG  . ASN A 1 303 ? 145.586 115.808 146.526 1.00 62.87  ? 303 ASN A CG  1 
ATOM   2308 O OD1 . ASN A 1 303 ? 146.668 116.122 147.016 1.00 65.61  ? 303 ASN A OD1 1 
ATOM   2309 N ND2 . ASN A 1 303 ? 145.019 116.495 145.545 1.00 70.71  ? 303 ASN A ND2 1 
ATOM   2310 N N   . THR A 1 304 ? 144.419 111.656 148.016 1.00 62.77  ? 304 THR A N   1 
ATOM   2311 C CA  . THR A 1 304 ? 143.611 110.624 148.662 1.00 52.87  ? 304 THR A CA  1 
ATOM   2312 C C   . THR A 1 304 ? 144.305 110.085 149.905 1.00 51.33  ? 304 THR A C   1 
ATOM   2313 O O   . THR A 1 304 ? 143.714 110.033 150.996 1.00 66.74  ? 304 THR A O   1 
ATOM   2314 C CB  . THR A 1 304 ? 143.324 109.489 147.683 1.00 55.52  ? 304 THR A CB  1 
ATOM   2315 O OG1 . THR A 1 304 ? 142.336 109.909 146.735 1.00 62.06  ? 304 THR A OG1 1 
ATOM   2316 C CG2 . THR A 1 304 ? 142.821 108.273 148.430 1.00 55.52  ? 304 THR A CG2 1 
ATOM   2317 N N   . PHE A 1 305 ? 145.576 109.702 149.760 1.00 54.46  ? 305 PHE A N   1 
ATOM   2318 C CA  . PHE A 1 305 ? 146.320 109.152 150.891 1.00 50.12  ? 305 PHE A CA  1 
ATOM   2319 C C   . PHE A 1 305 ? 146.356 110.126 152.060 1.00 55.96  ? 305 PHE A C   1 
ATOM   2320 O O   . PHE A 1 305 ? 146.039 109.763 153.199 1.00 65.56  ? 305 PHE A O   1 
ATOM   2321 C CB  . PHE A 1 305 ? 147.739 108.797 150.459 1.00 57.41  ? 305 PHE A CB  1 
ATOM   2322 C CG  . PHE A 1 305 ? 148.559 108.166 151.542 1.00 65.58  ? 305 PHE A CG  1 
ATOM   2323 C CD1 . PHE A 1 305 ? 149.609 108.855 152.118 1.00 63.74  ? 305 PHE A CD1 1 
ATOM   2324 C CD2 . PHE A 1 305 ? 148.288 106.884 151.979 1.00 69.45  ? 305 PHE A CD2 1 
ATOM   2325 C CE1 . PHE A 1 305 ? 150.368 108.282 153.112 1.00 61.41  ? 305 PHE A CE1 1 
ATOM   2326 C CE2 . PHE A 1 305 ? 149.047 106.306 152.975 1.00 65.49  ? 305 PHE A CE2 1 
ATOM   2327 C CZ  . PHE A 1 305 ? 150.087 107.008 153.540 1.00 60.93  ? 305 PHE A CZ  1 
ATOM   2328 N N   . PHE A 1 306 ? 146.724 111.378 151.798 1.00 62.48  ? 306 PHE A N   1 
ATOM   2329 C CA  . PHE A 1 306 ? 146.940 112.311 152.895 1.00 60.52  ? 306 PHE A CA  1 
ATOM   2330 C C   . PHE A 1 306 ? 145.629 112.791 153.497 1.00 58.75  ? 306 PHE A C   1 
ATOM   2331 O O   . PHE A 1 306 ? 145.571 113.084 154.690 1.00 70.92  ? 306 PHE A O   1 
ATOM   2332 C CB  . PHE A 1 306 ? 147.788 113.488 152.432 1.00 62.80  ? 306 PHE A CB  1 
ATOM   2333 C CG  . PHE A 1 306 ? 149.255 113.266 152.610 1.00 61.01  ? 306 PHE A CG  1 
ATOM   2334 C CD1 . PHE A 1 306 ? 149.771 112.992 153.858 1.00 59.38  ? 306 PHE A CD1 1 
ATOM   2335 C CD2 . PHE A 1 306 ? 150.114 113.320 151.532 1.00 65.21  ? 306 PHE A CD2 1 
ATOM   2336 C CE1 . PHE A 1 306 ? 151.113 112.783 154.030 1.00 63.73  ? 306 PHE A CE1 1 
ATOM   2337 C CE2 . PHE A 1 306 ? 151.458 113.110 151.698 1.00 66.91  ? 306 PHE A CE2 1 
ATOM   2338 C CZ  . PHE A 1 306 ? 151.959 112.841 152.949 1.00 68.22  ? 306 PHE A CZ  1 
ATOM   2339 N N   . LEU A 1 307 ? 144.561 112.879 152.704 1.00 51.90  ? 307 LEU A N   1 
ATOM   2340 C CA  . LEU A 1 307 ? 143.257 113.183 153.278 1.00 54.12  ? 307 LEU A CA  1 
ATOM   2341 C C   . LEU A 1 307 ? 142.844 112.099 154.261 1.00 66.91  ? 307 LEU A C   1 
ATOM   2342 O O   . LEU A 1 307 ? 142.469 112.385 155.408 1.00 70.17  ? 307 LEU A O   1 
ATOM   2343 C CB  . LEU A 1 307 ? 142.218 113.326 152.168 1.00 55.10  ? 307 LEU A CB  1 
ATOM   2344 C CG  . LEU A 1 307 ? 142.083 114.701 151.524 1.00 60.51  ? 307 LEU A CG  1 
ATOM   2345 C CD1 . LEU A 1 307 ? 140.870 114.739 150.621 1.00 63.59  ? 307 LEU A CD1 1 
ATOM   2346 C CD2 . LEU A 1 307 ? 141.982 115.771 152.585 1.00 63.01  ? 307 LEU A CD2 1 
ATOM   2347 N N   . LYS A 1 308 ? 142.942 110.835 153.833 1.00 79.46  ? 308 LYS A N   1 
ATOM   2348 C CA  . LYS A 1 308 ? 142.597 109.733 154.724 1.00 72.08  ? 308 LYS A CA  1 
ATOM   2349 C C   . LYS A 1 308 ? 143.475 109.739 155.968 1.00 72.11  ? 308 LYS A C   1 
ATOM   2350 O O   . LYS A 1 308 ? 143.010 109.418 157.067 1.00 73.80  ? 308 LYS A O   1 
ATOM   2351 C CB  . LYS A 1 308 ? 142.722 108.404 153.980 1.00 67.06  ? 308 LYS A CB  1 
ATOM   2352 C CG  . LYS A 1 308 ? 142.504 107.173 154.835 1.00 75.47  ? 308 LYS A CG  1 
ATOM   2353 C CD  . LYS A 1 308 ? 142.380 105.929 153.972 1.00 78.68  ? 308 LYS A CD  1 
ATOM   2354 C CE  . LYS A 1 308 ? 142.314 104.658 154.813 1.00 82.30  ? 308 LYS A CE  1 
ATOM   2355 N NZ  . LYS A 1 308 ? 141.277 104.725 155.880 1.00 78.06  ? 308 LYS A NZ  1 
ATOM   2356 N N   . HIS A 1 309 ? 144.747 110.107 155.815 1.00 72.89  ? 309 HIS A N   1 
ATOM   2357 C CA  . HIS A 1 309 ? 145.658 110.112 156.955 1.00 70.98  ? 309 HIS A CA  1 
ATOM   2358 C C   . HIS A 1 309 ? 145.329 111.235 157.930 1.00 72.21  ? 309 HIS A C   1 
ATOM   2359 O O   . HIS A 1 309 ? 145.273 111.023 159.146 1.00 78.62  ? 309 HIS A O   1 
ATOM   2360 C CB  . HIS A 1 309 ? 147.095 110.242 156.462 1.00 76.10  ? 309 HIS A CB  1 
ATOM   2361 C CG  . HIS A 1 309 ? 148.066 109.381 157.200 1.00 81.00  ? 309 HIS A CG  1 
ATOM   2362 N ND1 . HIS A 1 309 ? 149.107 109.901 157.937 1.00 80.96  ? 309 HIS A ND1 1 
ATOM   2363 C CD2 . HIS A 1 309 ? 148.155 108.036 157.317 1.00 83.22  ? 309 HIS A CD2 1 
ATOM   2364 C CE1 . HIS A 1 309 ? 149.797 108.913 158.476 1.00 83.39  ? 309 HIS A CE1 1 
ATOM   2365 N NE2 . HIS A 1 309 ? 149.240 107.771 158.116 1.00 87.61  ? 309 HIS A NE2 1 
ATOM   2366 N N   . ILE A 1 310 ? 145.114 112.443 157.410 1.00 69.12  ? 310 ILE A N   1 
ATOM   2367 C CA  . ILE A 1 310 ? 144.976 113.627 158.253 1.00 66.08  ? 310 ILE A CA  1 
ATOM   2368 C C   . ILE A 1 310 ? 143.641 113.619 158.981 1.00 70.91  ? 310 ILE A C   1 
ATOM   2369 O O   . ILE A 1 310 ? 143.577 113.848 160.194 1.00 69.23  ? 310 ILE A O   1 
ATOM   2370 C CB  . ILE A 1 310 ? 145.137 114.898 157.404 1.00 63.69  ? 310 ILE A CB  1 
ATOM   2371 C CG1 . ILE A 1 310 ? 146.551 114.993 156.849 1.00 67.91  ? 310 ILE A CG1 1 
ATOM   2372 C CG2 . ILE A 1 310 ? 144.824 116.122 158.227 1.00 68.96  ? 310 ILE A CG2 1 
ATOM   2373 C CD1 . ILE A 1 310 ? 146.833 116.300 156.196 1.00 68.64  ? 310 ILE A CD1 1 
ATOM   2374 N N   . PHE A 1 311 ? 142.553 113.368 158.257 1.00 81.30  ? 311 PHE A N   1 
ATOM   2375 C CA  . PHE A 1 311 ? 141.236 113.450 158.873 1.00 80.76  ? 311 PHE A CA  1 
ATOM   2376 C C   . PHE A 1 311 ? 140.773 112.123 159.455 1.00 81.87  ? 311 PHE A C   1 
ATOM   2377 O O   . PHE A 1 311 ? 139.641 112.039 159.940 1.00 83.80  ? 311 PHE A O   1 
ATOM   2378 C CB  . PHE A 1 311 ? 140.221 113.983 157.864 1.00 76.78  ? 311 PHE A CB  1 
ATOM   2379 C CG  . PHE A 1 311 ? 140.551 115.352 157.351 1.00 76.72  ? 311 PHE A CG  1 
ATOM   2380 C CD1 . PHE A 1 311 ? 141.221 116.257 158.152 1.00 78.57  ? 311 PHE A CD1 1 
ATOM   2381 C CD2 . PHE A 1 311 ? 140.212 115.727 156.067 1.00 80.07  ? 311 PHE A CD2 1 
ATOM   2382 C CE1 . PHE A 1 311 ? 141.535 117.515 157.686 1.00 79.44  ? 311 PHE A CE1 1 
ATOM   2383 C CE2 . PHE A 1 311 ? 140.526 116.986 155.596 1.00 81.76  ? 311 PHE A CE2 1 
ATOM   2384 C CZ  . PHE A 1 311 ? 141.189 117.879 156.406 1.00 79.27  ? 311 PHE A CZ  1 
ATOM   2385 N N   . VAL A 1 312 ? 141.632 111.103 159.422 1.00 81.18  ? 312 VAL A N   1 
ATOM   2386 C CA  . VAL A 1 312 ? 141.482 109.816 160.101 1.00 82.34  ? 312 VAL A CA  1 
ATOM   2387 C C   . VAL A 1 312 ? 140.043 109.298 160.087 1.00 83.19  ? 312 VAL A C   1 
ATOM   2388 O O   . VAL A 1 312 ? 139.390 109.178 161.129 1.00 81.98  ? 312 VAL A O   1 
ATOM   2389 C CB  . VAL A 1 312 ? 142.070 109.889 161.531 1.00 77.13  ? 312 VAL A CB  1 
ATOM   2390 C CG1 . VAL A 1 312 ? 141.362 110.916 162.422 1.00 75.99  ? 312 VAL A CG1 1 
ATOM   2391 C CG2 . VAL A 1 312 ? 142.119 108.503 162.182 1.00 78.47  ? 312 VAL A CG2 1 
ATOM   2392 N N   . PHE A 1 313 ? 139.534 108.993 158.898 1.00 81.42  ? 313 PHE A N   1 
ATOM   2393 C CA  . PHE A 1 313 ? 138.352 108.155 158.765 1.00 78.58  ? 313 PHE A CA  1 
ATOM   2394 C C   . PHE A 1 313 ? 138.763 106.844 158.112 1.00 79.70  ? 313 PHE A C   1 
ATOM   2395 O O   . PHE A 1 313 ? 139.632 106.828 157.234 1.00 77.37  ? 313 PHE A O   1 
ATOM   2396 C CB  . PHE A 1 313 ? 137.246 108.826 157.948 1.00 79.58  ? 313 PHE A CB  1 
ATOM   2397 C CG  . PHE A 1 313 ? 137.740 109.764 156.892 1.00 77.71  ? 313 PHE A CG  1 
ATOM   2398 C CD1 . PHE A 1 313 ? 138.197 109.283 155.682 1.00 82.41  ? 313 PHE A CD1 1 
ATOM   2399 C CD2 . PHE A 1 313 ? 137.696 111.129 157.088 1.00 72.11  ? 313 PHE A CD2 1 
ATOM   2400 C CE1 . PHE A 1 313 ? 138.635 110.146 154.702 1.00 82.48  ? 313 PHE A CE1 1 
ATOM   2401 C CE2 . PHE A 1 313 ? 138.129 111.992 156.110 1.00 75.94  ? 313 PHE A CE2 1 
ATOM   2402 C CZ  . PHE A 1 313 ? 138.600 111.502 154.918 1.00 79.55  ? 313 PHE A CZ  1 
ATOM   2403 N N   . GLN A 1 314 ? 138.147 105.750 158.547 1.00 93.36  ? 314 GLN A N   1 
ATOM   2404 C CA  . GLN A 1 314 ? 138.488 104.439 158.015 1.00 93.91  ? 314 GLN A CA  1 
ATOM   2405 C C   . GLN A 1 314 ? 138.095 104.341 156.547 1.00 96.18  ? 314 GLN A C   1 
ATOM   2406 O O   . GLN A 1 314 ? 137.303 105.142 156.044 1.00 97.88  ? 314 GLN A O   1 
ATOM   2407 C CB  . GLN A 1 314 ? 137.786 103.349 158.821 1.00 92.76  ? 314 GLN A CB  1 
ATOM   2408 C CG  . GLN A 1 314 ? 137.840 103.564 160.322 1.00 96.07  ? 314 GLN A CG  1 
ATOM   2409 C CD  . GLN A 1 314 ? 136.798 102.749 161.058 1.00 98.88  ? 314 GLN A CD  1 
ATOM   2410 O OE1 . GLN A 1 314 ? 136.018 102.020 160.446 1.00 100.48 ? 314 GLN A OE1 1 
ATOM   2411 N NE2 . GLN A 1 314 ? 136.777 102.870 162.380 1.00 94.16  ? 314 GLN A NE2 1 
ATOM   2412 N N   . ALA A 1 315 ? 138.661 103.349 155.856 1.00 93.48  ? 315 ALA A N   1 
ATOM   2413 C CA  . ALA A 1 315 ? 138.346 103.157 154.444 1.00 91.27  ? 315 ALA A CA  1 
ATOM   2414 C C   . ALA A 1 315 ? 136.882 102.794 154.245 1.00 91.33  ? 315 ALA A C   1 
ATOM   2415 O O   . ALA A 1 315 ? 136.288 103.118 153.211 1.00 88.93  ? 315 ALA A O   1 
ATOM   2416 C CB  . ALA A 1 315 ? 139.246 102.077 153.847 1.00 88.91  ? 315 ALA A CB  1 
ATOM   2417 N N   . SER A 1 316 ? 136.282 102.118 155.225 1.00 95.62  ? 316 SER A N   1 
ATOM   2418 C CA  . SER A 1 316 ? 134.882 101.731 155.114 1.00 95.87  ? 316 SER A CA  1 
ATOM   2419 C C   . SER A 1 316 ? 133.935 102.912 155.286 1.00 96.33  ? 316 SER A C   1 
ATOM   2420 O O   . SER A 1 316 ? 132.741 102.777 155.004 1.00 96.09  ? 316 SER A O   1 
ATOM   2421 C CB  . SER A 1 316 ? 134.557 100.654 156.148 1.00 98.10  ? 316 SER A CB  1 
ATOM   2422 O OG  . SER A 1 316 ? 135.536 99.632  156.140 1.00 99.47  ? 316 SER A OG  1 
ATOM   2423 N N   . HIS A 1 317 ? 134.433 104.051 155.752 1.00 90.01  ? 317 HIS A N   1 
ATOM   2424 C CA  . HIS A 1 317 ? 133.573 105.202 155.973 1.00 86.67  ? 317 HIS A CA  1 
ATOM   2425 C C   . HIS A 1 317 ? 133.129 105.793 154.637 1.00 83.68  ? 317 HIS A C   1 
ATOM   2426 O O   . HIS A 1 317 ? 133.896 105.785 153.672 1.00 86.05  ? 317 HIS A O   1 
ATOM   2427 C CB  . HIS A 1 317 ? 134.307 106.254 156.801 1.00 83.47  ? 317 HIS A CB  1 
ATOM   2428 C CG  . HIS A 1 317 ? 133.420 107.334 157.330 1.00 84.23  ? 317 HIS A CG  1 
ATOM   2429 N ND1 . HIS A 1 317 ? 132.987 107.365 158.637 1.00 85.20  ? 317 HIS A ND1 1 
ATOM   2430 C CD2 . HIS A 1 317 ? 132.900 108.432 156.735 1.00 84.51  ? 317 HIS A CD2 1 
ATOM   2431 C CE1 . HIS A 1 317 ? 132.225 108.427 158.820 1.00 89.74  ? 317 HIS A CE1 1 
ATOM   2432 N NE2 . HIS A 1 317 ? 132.156 109.091 157.681 1.00 87.94  ? 317 HIS A NE2 1 
ATOM   2433 N N   . PRO A 1 318 ? 131.898 106.302 154.547 1.00 79.06  ? 318 PRO A N   1 
ATOM   2434 C CA  . PRO A 1 318 ? 131.440 106.894 153.281 1.00 77.57  ? 318 PRO A CA  1 
ATOM   2435 C C   . PRO A 1 318 ? 132.295 108.043 152.790 1.00 81.51  ? 318 PRO A C   1 
ATOM   2436 O O   . PRO A 1 318 ? 132.423 108.213 151.573 1.00 87.36  ? 318 PRO A O   1 
ATOM   2437 C CB  . PRO A 1 318 ? 130.018 107.356 153.612 1.00 79.64  ? 318 PRO A CB  1 
ATOM   2438 C CG  . PRO A 1 318 ? 129.573 106.412 154.663 1.00 84.28  ? 318 PRO A CG  1 
ATOM   2439 C CD  . PRO A 1 318 ? 130.792 106.143 155.505 1.00 84.75  ? 318 PRO A CD  1 
ATOM   2440 N N   . LEU A 1 319 ? 132.912 108.819 153.682 1.00 79.08  ? 319 LEU A N   1 
ATOM   2441 C CA  . LEU A 1 319 ? 133.747 109.932 153.246 1.00 75.79  ? 319 LEU A CA  1 
ATOM   2442 C C   . LEU A 1 319 ? 134.993 109.476 152.503 1.00 77.40  ? 319 LEU A C   1 
ATOM   2443 O O   . LEU A 1 319 ? 135.683 110.316 151.920 1.00 80.63  ? 319 LEU A O   1 
ATOM   2444 C CB  . LEU A 1 319 ? 134.162 110.792 154.439 1.00 78.28  ? 319 LEU A CB  1 
ATOM   2445 C CG  . LEU A 1 319 ? 133.154 111.793 155.000 1.00 77.08  ? 319 LEU A CG  1 
ATOM   2446 C CD1 . LEU A 1 319 ? 133.305 111.910 156.500 1.00 73.63  ? 319 LEU A CD1 1 
ATOM   2447 C CD2 . LEU A 1 319 ? 133.336 113.142 154.350 1.00 78.29  ? 319 LEU A CD2 1 
ATOM   2448 N N   . SER A 1 320 ? 135.306 108.182 152.520 1.00 74.31  ? 320 SER A N   1 
ATOM   2449 C CA  . SER A 1 320 ? 136.460 107.677 151.792 1.00 72.17  ? 320 SER A CA  1 
ATOM   2450 C C   . SER A 1 320 ? 136.053 107.080 150.452 1.00 71.93  ? 320 SER A C   1 
ATOM   2451 O O   . SER A 1 320 ? 136.471 107.567 149.394 1.00 75.34  ? 320 SER A O   1 
ATOM   2452 C CB  . SER A 1 320 ? 137.194 106.632 152.630 1.00 75.39  ? 320 SER A CB  1 
ATOM   2453 O OG  . SER A 1 320 ? 138.119 105.906 151.842 1.00 85.64  ? 320 SER A OG  1 
ATOM   2454 N N   . TRP A 1 321 ? 135.209 106.048 150.475 1.00 71.22  ? 321 TRP A N   1 
ATOM   2455 C CA  . TRP A 1 321 ? 134.877 105.381 149.223 1.00 71.11  ? 321 TRP A CA  1 
ATOM   2456 C C   . TRP A 1 321 ? 133.929 106.217 148.377 1.00 66.98  ? 321 TRP A C   1 
ATOM   2457 O O   . TRP A 1 321 ? 133.997 106.159 147.145 1.00 76.01  ? 321 TRP A O   1 
ATOM   2458 C CB  . TRP A 1 321 ? 134.299 103.989 149.484 1.00 71.55  ? 321 TRP A CB  1 
ATOM   2459 C CG  . TRP A 1 321 ? 133.079 103.942 150.333 1.00 69.08  ? 321 TRP A CG  1 
ATOM   2460 C CD1 . TRP A 1 321 ? 133.023 103.658 151.659 1.00 71.35  ? 321 TRP A CD1 1 
ATOM   2461 C CD2 . TRP A 1 321 ? 131.728 104.150 149.909 1.00 70.93  ? 321 TRP A CD2 1 
ATOM   2462 N NE1 . TRP A 1 321 ? 131.723 103.690 152.096 1.00 71.33  ? 321 TRP A NE1 1 
ATOM   2463 C CE2 . TRP A 1 321 ? 130.909 103.990 151.038 1.00 69.59  ? 321 TRP A CE2 1 
ATOM   2464 C CE3 . TRP A 1 321 ? 131.133 104.464 148.685 1.00 74.17  ? 321 TRP A CE3 1 
ATOM   2465 C CZ2 . TRP A 1 321 ? 129.531 104.136 150.983 1.00 74.39  ? 321 TRP A CZ2 1 
ATOM   2466 C CZ3 . TRP A 1 321 ? 129.765 104.606 148.633 1.00 74.58  ? 321 TRP A CZ3 1 
ATOM   2467 C CH2 . TRP A 1 321 ? 128.979 104.445 149.773 1.00 77.52  ? 321 TRP A CH2 1 
ATOM   2468 N N   . GLY A 1 322 ? 133.053 107.006 148.999 1.00 60.81  ? 322 GLY A N   1 
ATOM   2469 C CA  . GLY A 1 322 ? 132.254 107.934 148.223 1.00 65.55  ? 322 GLY A CA  1 
ATOM   2470 C C   . GLY A 1 322 ? 133.111 108.941 147.484 1.00 74.83  ? 322 GLY A C   1 
ATOM   2471 O O   . GLY A 1 322 ? 132.871 109.235 146.310 1.00 83.57  ? 322 GLY A O   1 
ATOM   2472 N N   . ARG A 1 323 ? 134.137 109.468 148.153 1.00 62.09  ? 323 ARG A N   1 
ATOM   2473 C CA  . ARG A 1 323 ? 135.039 110.401 147.492 1.00 57.91  ? 323 ARG A CA  1 
ATOM   2474 C C   . ARG A 1 323 ? 135.801 109.725 146.361 1.00 61.78  ? 323 ARG A C   1 
ATOM   2475 O O   . ARG A 1 323 ? 136.004 110.325 145.302 1.00 67.48  ? 323 ARG A O   1 
ATOM   2476 C CB  . ARG A 1 323 ? 136.012 111.010 148.497 1.00 57.85  ? 323 ARG A CB  1 
ATOM   2477 C CG  . ARG A 1 323 ? 136.977 111.987 147.864 1.00 56.87  ? 323 ARG A CG  1 
ATOM   2478 C CD  . ARG A 1 323 ? 138.088 112.382 148.809 1.00 54.27  ? 323 ARG A CD  1 
ATOM   2479 N NE  . ARG A 1 323 ? 139.187 113.011 148.090 1.00 59.14  ? 323 ARG A NE  1 
ATOM   2480 C CZ  . ARG A 1 323 ? 140.070 112.354 147.353 1.00 63.98  ? 323 ARG A CZ  1 
ATOM   2481 N NH1 . ARG A 1 323 ? 140.036 111.037 147.244 1.00 63.91  ? 323 ARG A NH1 1 
ATOM   2482 N NH2 . ARG A 1 323 ? 141.012 113.035 146.709 1.00 63.64  ? 323 ARG A NH2 1 
ATOM   2483 N N   . ILE A 1 324 ? 136.237 108.480 146.564 1.00 66.09  ? 324 ILE A N   1 
ATOM   2484 C CA  . ILE A 1 324 ? 136.951 107.782 145.494 1.00 61.21  ? 324 ILE A CA  1 
ATOM   2485 C C   . ILE A 1 324 ? 136.042 107.568 144.287 1.00 65.56  ? 324 ILE A C   1 
ATOM   2486 O O   . ILE A 1 324 ? 136.453 107.772 143.136 1.00 72.09  ? 324 ILE A O   1 
ATOM   2487 C CB  . ILE A 1 324 ? 137.534 106.452 145.999 1.00 62.85  ? 324 ILE A CB  1 
ATOM   2488 C CG1 . ILE A 1 324 ? 138.418 106.679 147.218 1.00 68.80  ? 324 ILE A CG1 1 
ATOM   2489 C CG2 . ILE A 1 324 ? 138.355 105.808 144.913 1.00 65.81  ? 324 ILE A CG2 1 
ATOM   2490 C CD1 . ILE A 1 324 ? 139.530 107.650 146.977 1.00 71.63  ? 324 ILE A CD1 1 
ATOM   2491 N N   . LEU A 1 325 ? 134.798 107.141 144.525 1.00 67.23  ? 325 LEU A N   1 
ATOM   2492 C CA  . LEU A 1 325 ? 133.861 106.948 143.422 1.00 65.37  ? 325 LEU A CA  1 
ATOM   2493 C C   . LEU A 1 325 ? 133.615 108.253 142.682 1.00 67.68  ? 325 LEU A C   1 
ATOM   2494 O O   . LEU A 1 325 ? 133.604 108.287 141.443 1.00 75.81  ? 325 LEU A O   1 
ATOM   2495 C CB  . LEU A 1 325 ? 132.538 106.386 143.939 1.00 63.99  ? 325 LEU A CB  1 
ATOM   2496 C CG  . LEU A 1 325 ? 132.510 104.980 144.535 1.00 71.97  ? 325 LEU A CG  1 
ATOM   2497 C CD1 . LEU A 1 325 ? 131.094 104.442 144.528 1.00 70.06  ? 325 LEU A CD1 1 
ATOM   2498 C CD2 . LEU A 1 325 ? 133.441 104.048 143.788 1.00 72.48  ? 325 LEU A CD2 1 
ATOM   2499 N N   . PHE A 1 326 ? 133.417 109.340 143.428 1.00 57.60  ? 326 PHE A N   1 
ATOM   2500 C CA  . PHE A 1 326 ? 133.188 110.635 142.803 1.00 61.49  ? 326 PHE A CA  1 
ATOM   2501 C C   . PHE A 1 326 ? 134.394 111.074 141.984 1.00 64.47  ? 326 PHE A C   1 
ATOM   2502 O O   . PHE A 1 326 ? 134.244 111.628 140.888 1.00 62.24  ? 326 PHE A O   1 
ATOM   2503 C CB  . PHE A 1 326 ? 132.860 111.666 143.877 1.00 60.42  ? 326 PHE A CB  1 
ATOM   2504 C CG  . PHE A 1 326 ? 132.782 113.061 143.365 1.00 59.56  ? 326 PHE A CG  1 
ATOM   2505 C CD1 . PHE A 1 326 ? 131.946 113.378 142.317 1.00 56.17  ? 326 PHE A CD1 1 
ATOM   2506 C CD2 . PHE A 1 326 ? 133.542 114.059 143.935 1.00 60.72  ? 326 PHE A CD2 1 
ATOM   2507 C CE1 . PHE A 1 326 ? 131.874 114.660 141.847 1.00 55.90  ? 326 PHE A CE1 1 
ATOM   2508 C CE2 . PHE A 1 326 ? 133.472 115.341 143.467 1.00 65.74  ? 326 PHE A CE2 1 
ATOM   2509 C CZ  . PHE A 1 326 ? 132.634 115.642 142.425 1.00 60.94  ? 326 PHE A CZ  1 
ATOM   2510 N N   . ILE A 1 327 ? 135.599 110.828 142.494 1.00 59.43  ? 327 ILE A N   1 
ATOM   2511 C CA  . ILE A 1 327 ? 136.798 111.239 141.779 1.00 51.27  ? 327 ILE A CA  1 
ATOM   2512 C C   . ILE A 1 327 ? 136.957 110.441 140.494 1.00 61.85  ? 327 ILE A C   1 
ATOM   2513 O O   . ILE A 1 327 ? 137.374 110.981 139.470 1.00 76.03  ? 327 ILE A O   1 
ATOM   2514 C CB  . ILE A 1 327 ? 138.031 111.122 142.690 1.00 54.11  ? 327 ILE A CB  1 
ATOM   2515 C CG1 . ILE A 1 327 ? 138.123 112.351 143.588 1.00 59.09  ? 327 ILE A CG1 1 
ATOM   2516 C CG2 . ILE A 1 327 ? 139.298 110.982 141.873 1.00 52.37  ? 327 ILE A CG2 1 
ATOM   2517 C CD1 . ILE A 1 327 ? 138.169 113.648 142.829 1.00 56.72  ? 327 ILE A CD1 1 
ATOM   2518 N N   . GLY A 1 328 ? 136.615 109.152 140.511 1.00 57.91  ? 328 GLY A N   1 
ATOM   2519 C CA  . GLY A 1 328 ? 136.656 108.385 139.271 1.00 58.73  ? 328 GLY A CA  1 
ATOM   2520 C C   . GLY A 1 328 ? 135.641 108.867 138.248 1.00 60.47  ? 328 GLY A C   1 
ATOM   2521 O O   . GLY A 1 328 ? 135.946 108.986 137.046 1.00 59.55  ? 328 GLY A O   1 
ATOM   2522 N N   . GLY A 1 329 ? 134.418 109.143 138.707 1.00 52.37  ? 329 GLY A N   1 
ATOM   2523 C CA  . GLY A 1 329 ? 133.400 109.662 137.810 1.00 53.82  ? 329 GLY A CA  1 
ATOM   2524 C C   . GLY A 1 329 ? 133.791 110.992 137.199 1.00 50.82  ? 329 GLY A C   1 
ATOM   2525 O O   . GLY A 1 329 ? 133.473 111.273 136.043 1.00 49.87  ? 329 GLY A O   1 
ATOM   2526 N N   . ILE A 1 330 ? 134.469 111.836 137.975 1.00 50.69  ? 330 ILE A N   1 
ATOM   2527 C CA  . ILE A 1 330 ? 135.045 113.058 137.423 1.00 48.14  ? 330 ILE A CA  1 
ATOM   2528 C C   . ILE A 1 330 ? 136.159 112.722 136.440 1.00 49.67  ? 330 ILE A C   1 
ATOM   2529 O O   . ILE A 1 330 ? 136.293 113.352 135.386 1.00 55.13  ? 330 ILE A O   1 
ATOM   2530 C CB  . ILE A 1 330 ? 135.572 113.950 138.556 1.00 50.10  ? 330 ILE A CB  1 
ATOM   2531 C CG1 . ILE A 1 330 ? 134.482 114.837 139.127 1.00 55.89  ? 330 ILE A CG1 1 
ATOM   2532 C CG2 . ILE A 1 330 ? 136.650 114.848 138.044 1.00 49.56  ? 330 ILE A CG2 1 
ATOM   2533 C CD1 . ILE A 1 330 ? 135.051 115.870 140.068 1.00 63.66  ? 330 ILE A CD1 1 
ATOM   2534 N N   . THR A 1 331 ? 136.974 111.722 136.778 1.00 45.63  ? 331 THR A N   1 
ATOM   2535 C CA  . THR A 1 331 ? 138.212 111.460 136.058 1.00 46.33  ? 331 THR A CA  1 
ATOM   2536 C C   . THR A 1 331 ? 137.952 111.067 134.616 1.00 50.62  ? 331 THR A C   1 
ATOM   2537 O O   . THR A 1 331 ? 138.694 111.475 133.715 1.00 56.38  ? 331 THR A O   1 
ATOM   2538 C CB  . THR A 1 331 ? 138.998 110.365 136.777 1.00 53.63  ? 331 THR A CB  1 
ATOM   2539 O OG1 . THR A 1 331 ? 139.549 110.888 137.991 1.00 55.91  ? 331 THR A OG1 1 
ATOM   2540 C CG2 . THR A 1 331 ? 140.116 109.840 135.903 1.00 53.44  ? 331 THR A CG2 1 
ATOM   2541 N N   . ALA A 1 332 ? 136.912 110.268 134.373 1.00 49.81  ? 332 ALA A N   1 
ATOM   2542 C CA  . ALA A 1 332 ? 136.680 109.807 133.002 1.00 44.79  ? 332 ALA A CA  1 
ATOM   2543 C C   . ALA A 1 332 ? 136.533 110.961 132.004 1.00 48.14  ? 332 ALA A C   1 
ATOM   2544 O O   . ALA A 1 332 ? 137.374 111.078 131.090 1.00 61.65  ? 332 ALA A O   1 
ATOM   2545 C CB  . ALA A 1 332 ? 135.492 108.842 132.974 1.00 45.88  ? 332 ALA A CB  1 
ATOM   2546 N N   . PRO A 1 333 ? 135.532 111.847 132.116 1.00 46.24  ? 333 PRO A N   1 
ATOM   2547 C CA  . PRO A 1 333 ? 135.468 112.968 131.166 1.00 48.83  ? 333 PRO A CA  1 
ATOM   2548 C C   . PRO A 1 333 ? 136.664 113.891 131.243 1.00 47.59  ? 333 PRO A C   1 
ATOM   2549 O O   . PRO A 1 333 ? 137.044 114.476 130.225 1.00 58.27  ? 333 PRO A O   1 
ATOM   2550 C CB  . PRO A 1 333 ? 134.175 113.691 131.560 1.00 49.57  ? 333 PRO A CB  1 
ATOM   2551 C CG  . PRO A 1 333 ? 133.985 113.363 132.963 1.00 47.13  ? 333 PRO A CG  1 
ATOM   2552 C CD  . PRO A 1 333 ? 134.466 111.959 133.126 1.00 51.83  ? 333 PRO A CD  1 
ATOM   2553 N N   . THR A 1 334 ? 137.269 114.048 132.421 1.00 39.38  ? 334 THR A N   1 
ATOM   2554 C CA  . THR A 1 334 ? 138.460 114.882 132.529 1.00 38.77  ? 334 THR A CA  1 
ATOM   2555 C C   . THR A 1 334 ? 139.614 114.302 131.727 1.00 47.80  ? 334 THR A C   1 
ATOM   2556 O O   . THR A 1 334 ? 140.331 115.035 131.040 1.00 65.16  ? 334 THR A O   1 
ATOM   2557 C CB  . THR A 1 334 ? 138.863 115.037 133.989 1.00 48.85  ? 334 THR A CB  1 
ATOM   2558 O OG1 . THR A 1 334 ? 138.065 116.059 134.591 1.00 65.47  ? 334 THR A OG1 1 
ATOM   2559 C CG2 . THR A 1 334 ? 140.315 115.425 134.088 1.00 43.71  ? 334 THR A CG2 1 
ATOM   2560 N N   . VAL A 1 335 ? 139.813 112.986 131.802 1.00 43.70  ? 335 VAL A N   1 
ATOM   2561 C CA  . VAL A 1 335 ? 140.858 112.352 131.008 1.00 37.33  ? 335 VAL A CA  1 
ATOM   2562 C C   . VAL A 1 335 ? 140.593 112.559 129.527 1.00 41.39  ? 335 VAL A C   1 
ATOM   2563 O O   . VAL A 1 335 ? 141.502 112.904 128.759 1.00 54.87  ? 335 VAL A O   1 
ATOM   2564 C CB  . VAL A 1 335 ? 140.962 110.858 131.353 1.00 46.19  ? 335 VAL A CB  1 
ATOM   2565 C CG1 . VAL A 1 335 ? 141.659 110.117 130.240 1.00 53.60  ? 335 VAL A CG1 1 
ATOM   2566 C CG2 . VAL A 1 335 ? 141.696 110.668 132.657 1.00 49.48  ? 335 VAL A CG2 1 
ATOM   2567 N N   . ARG A 1 336 ? 139.344 112.359 129.099 1.00 51.78  ? 336 ARG A N   1 
ATOM   2568 C CA  . ARG A 1 336 ? 139.047 112.524 127.679 1.00 56.83  ? 336 ARG A CA  1 
ATOM   2569 C C   . ARG A 1 336 ? 139.273 113.963 127.220 1.00 56.45  ? 336 ARG A C   1 
ATOM   2570 O O   . ARG A 1 336 ? 139.836 114.199 126.144 1.00 63.61  ? 336 ARG A O   1 
ATOM   2571 C CB  . ARG A 1 336 ? 137.619 112.081 127.384 1.00 56.88  ? 336 ARG A CB  1 
ATOM   2572 C CG  . ARG A 1 336 ? 137.419 111.663 125.948 1.00 64.39  ? 336 ARG A CG  1 
ATOM   2573 C CD  . ARG A 1 336 ? 138.381 110.553 125.565 1.00 70.27  ? 336 ARG A CD  1 
ATOM   2574 N NE  . ARG A 1 336 ? 137.746 109.242 125.605 1.00 75.52  ? 336 ARG A NE  1 
ATOM   2575 C CZ  . ARG A 1 336 ? 138.404 108.094 125.669 1.00 71.24  ? 336 ARG A CZ  1 
ATOM   2576 N NH1 . ARG A 1 336 ? 139.724 108.059 125.728 1.00 65.63  ? 336 ARG A NH1 1 
ATOM   2577 N NH2 . ARG A 1 336 ? 137.721 106.954 125.676 1.00 68.84  ? 336 ARG A NH2 1 
ATOM   2578 N N   . GLN A 1 337 ? 138.859 114.939 128.030 1.00 46.87  ? 337 GLN A N   1 
ATOM   2579 C CA  . GLN A 1 337 ? 139.039 116.341 127.666 1.00 37.40  ? 337 GLN A CA  1 
ATOM   2580 C C   . GLN A 1 337 ? 140.507 116.736 127.646 1.00 46.93  ? 337 GLN A C   1 
ATOM   2581 O O   . GLN A 1 337 ? 140.932 117.508 126.781 1.00 62.63  ? 337 GLN A O   1 
ATOM   2582 C CB  . GLN A 1 337 ? 138.274 117.235 128.632 1.00 38.24  ? 337 GLN A CB  1 
ATOM   2583 C CG  . GLN A 1 337 ? 136.788 117.125 128.506 1.00 43.93  ? 337 GLN A CG  1 
ATOM   2584 C CD  . GLN A 1 337 ? 136.086 118.306 129.102 1.00 48.07  ? 337 GLN A CD  1 
ATOM   2585 O OE1 . GLN A 1 337 ? 136.695 119.111 129.792 1.00 53.85  ? 337 GLN A OE1 1 
ATOM   2586 N NE2 . GLN A 1 337 ? 134.798 118.424 128.835 1.00 52.59  ? 337 GLN A NE2 1 
ATOM   2587 N N   . TYR A 1 338 ? 141.296 116.244 128.602 1.00 48.73  ? 338 TYR A N   1 
ATOM   2588 C CA  . TYR A 1 338 ? 142.719 116.557 128.599 1.00 40.77  ? 338 TYR A CA  1 
ATOM   2589 C C   . TYR A 1 338 ? 143.404 115.968 127.380 1.00 51.86  ? 338 TYR A C   1 
ATOM   2590 O O   . TYR A 1 338 ? 144.265 116.612 126.774 1.00 64.34  ? 338 TYR A O   1 
ATOM   2591 C CB  . TYR A 1 338 ? 143.385 116.051 129.871 1.00 44.08  ? 338 TYR A CB  1 
ATOM   2592 C CG  . TYR A 1 338 ? 144.820 116.490 129.993 1.00 47.83  ? 338 TYR A CG  1 
ATOM   2593 C CD1 . TYR A 1 338 ? 145.139 117.753 130.455 1.00 55.43  ? 338 TYR A CD1 1 
ATOM   2594 C CD2 . TYR A 1 338 ? 145.856 115.649 129.633 1.00 56.29  ? 338 TYR A CD2 1 
ATOM   2595 C CE1 . TYR A 1 338 ? 146.446 118.160 130.566 1.00 52.93  ? 338 TYR A CE1 1 
ATOM   2596 C CE2 . TYR A 1 338 ? 147.167 116.051 129.738 1.00 55.90  ? 338 TYR A CE2 1 
ATOM   2597 C CZ  . TYR A 1 338 ? 147.455 117.306 130.204 1.00 51.59  ? 338 TYR A CZ  1 
ATOM   2598 O OH  . TYR A 1 338 ? 148.761 117.711 130.310 1.00 58.87  ? 338 TYR A OH  1 
ATOM   2599 N N   . TYR A 1 339 ? 143.042 114.739 127.004 1.00 54.92  ? 339 TYR A N   1 
ATOM   2600 C CA  . TYR A 1 339 ? 143.602 114.167 125.786 1.00 56.30  ? 339 TYR A CA  1 
ATOM   2601 C C   . TYR A 1 339 ? 143.225 114.995 124.569 1.00 60.22  ? 339 TYR A C   1 
ATOM   2602 O O   . TYR A 1 339 ? 144.072 115.277 123.711 1.00 68.97  ? 339 TYR A O   1 
ATOM   2603 C CB  . TYR A 1 339 ? 143.127 112.731 125.606 1.00 58.23  ? 339 TYR A CB  1 
ATOM   2604 C CG  . TYR A 1 339 ? 143.610 112.112 124.321 1.00 61.43  ? 339 TYR A CG  1 
ATOM   2605 C CD1 . TYR A 1 339 ? 144.909 111.657 124.199 1.00 61.93  ? 339 TYR A CD1 1 
ATOM   2606 C CD2 . TYR A 1 339 ? 142.771 111.993 123.228 1.00 59.35  ? 339 TYR A CD2 1 
ATOM   2607 C CE1 . TYR A 1 339 ? 145.355 111.089 123.035 1.00 56.97  ? 339 TYR A CE1 1 
ATOM   2608 C CE2 . TYR A 1 339 ? 143.210 111.432 122.056 1.00 55.83  ? 339 TYR A CE2 1 
ATOM   2609 C CZ  . TYR A 1 339 ? 144.504 110.982 121.965 1.00 58.47  ? 339 TYR A CZ  1 
ATOM   2610 O OH  . TYR A 1 339 ? 144.951 110.418 120.795 1.00 69.52  ? 339 TYR A OH  1 
ATOM   2611 N N   . ALA A 1 340 ? 141.956 115.400 124.479 1.00 57.07  ? 340 ALA A N   1 
ATOM   2612 C CA  . ALA A 1 340 ? 141.520 116.198 123.340 1.00 54.04  ? 340 ALA A CA  1 
ATOM   2613 C C   . ALA A 1 340 ? 142.273 117.518 123.269 1.00 55.65  ? 340 ALA A C   1 
ATOM   2614 O O   . ALA A 1 340 ? 142.696 117.940 122.189 1.00 68.58  ? 340 ALA A O   1 
ATOM   2615 C CB  . ALA A 1 340 ? 140.015 116.442 123.415 1.00 56.40  ? 340 ALA A CB  1 
ATOM   2616 N N   . TYR A 1 341 ? 142.452 118.185 124.410 1.00 56.45  ? 341 TYR A N   1 
ATOM   2617 C CA  . TYR A 1 341 ? 143.187 119.445 124.414 1.00 58.74  ? 341 TYR A CA  1 
ATOM   2618 C C   . TYR A 1 341 ? 144.646 119.239 124.039 1.00 58.73  ? 341 TYR A C   1 
ATOM   2619 O O   . TYR A 1 341 ? 145.212 120.029 123.278 1.00 68.31  ? 341 TYR A O   1 
ATOM   2620 C CB  . TYR A 1 341 ? 143.085 120.116 125.781 1.00 57.67  ? 341 TYR A CB  1 
ATOM   2621 C CG  . TYR A 1 341 ? 143.867 121.404 125.882 1.00 57.40  ? 341 TYR A CG  1 
ATOM   2622 C CD1 . TYR A 1 341 ? 143.322 122.601 125.453 1.00 60.26  ? 341 TYR A CD1 1 
ATOM   2623 C CD2 . TYR A 1 341 ? 145.146 121.423 126.407 1.00 63.55  ? 341 TYR A CD2 1 
ATOM   2624 C CE1 . TYR A 1 341 ? 144.029 123.778 125.544 1.00 61.66  ? 341 TYR A CE1 1 
ATOM   2625 C CE2 . TYR A 1 341 ? 145.860 122.597 126.498 1.00 67.59  ? 341 TYR A CE2 1 
ATOM   2626 C CZ  . TYR A 1 341 ? 145.296 123.770 126.065 1.00 66.53  ? 341 TYR A CZ  1 
ATOM   2627 O OH  . TYR A 1 341 ? 146.004 124.945 126.155 1.00 68.89  ? 341 TYR A OH  1 
ATOM   2628 N N   . LEU A 1 342 ? 145.278 118.194 124.570 1.00 53.06  ? 342 LEU A N   1 
ATOM   2629 C CA  . LEU A 1 342 ? 146.700 117.994 124.327 1.00 57.51  ? 342 LEU A CA  1 
ATOM   2630 C C   . LEU A 1 342 ? 146.979 117.659 122.869 1.00 61.39  ? 342 LEU A C   1 
ATOM   2631 O O   . LEU A 1 342 ? 147.939 118.173 122.284 1.00 66.12  ? 342 LEU A O   1 
ATOM   2632 C CB  . LEU A 1 342 ? 147.236 116.892 125.236 1.00 61.99  ? 342 LEU A CB  1 
ATOM   2633 C CG  . LEU A 1 342 ? 148.755 116.764 125.288 1.00 62.86  ? 342 LEU A CG  1 
ATOM   2634 C CD1 . LEU A 1 342 ? 149.393 118.116 125.532 1.00 62.40  ? 342 LEU A CD1 1 
ATOM   2635 C CD2 . LEU A 1 342 ? 149.159 115.774 126.357 1.00 62.22  ? 342 LEU A CD2 1 
ATOM   2636 N N   . THR A 1 343 ? 146.161 116.797 122.264 1.00 61.53  ? 343 THR A N   1 
ATOM   2637 C CA  . THR A 1 343 ? 146.464 116.339 120.912 1.00 63.25  ? 343 THR A CA  1 
ATOM   2638 C C   . THR A 1 343 ? 145.980 117.325 119.856 1.00 64.07  ? 343 THR A C   1 
ATOM   2639 O O   . THR A 1 343 ? 146.776 117.849 119.070 1.00 69.69  ? 343 THR A O   1 
ATOM   2640 C CB  . THR A 1 343 ? 145.846 114.965 120.669 1.00 66.16  ? 343 THR A CB  1 
ATOM   2641 O OG1 . THR A 1 343 ? 144.437 115.029 120.908 1.00 69.45  ? 343 THR A OG1 1 
ATOM   2642 C CG2 . THR A 1 343 ? 146.467 113.953 121.596 1.00 67.10  ? 343 THR A CG2 1 
ATOM   2643 N N   . ASP A 1 344 ? 144.678 117.583 119.823 1.00 72.08  ? 344 ASP A N   1 
ATOM   2644 C CA  . ASP A 1 344 ? 144.094 118.355 118.736 1.00 75.02  ? 344 ASP A CA  1 
ATOM   2645 C C   . ASP A 1 344 ? 144.629 119.778 118.738 1.00 79.70  ? 344 ASP A C   1 
ATOM   2646 O O   . ASP A 1 344 ? 144.414 120.532 119.690 1.00 69.68  ? 344 ASP A O   1 
ATOM   2647 C CB  . ASP A 1 344 ? 142.574 118.358 118.856 1.00 70.38  ? 344 ASP A CB  1 
ATOM   2648 C CG  . ASP A 1 344 ? 141.891 118.490 117.517 1.00 76.50  ? 344 ASP A CG  1 
ATOM   2649 O OD1 . ASP A 1 344 ? 142.368 117.870 116.543 1.00 79.32  ? 344 ASP A OD1 1 
ATOM   2650 O OD2 . ASP A 1 344 ? 140.880 119.215 117.435 1.00 80.52  ? 344 ASP A OD2 1 
ATOM   2651 N N   . THR A 1 345 ? 145.327 120.143 117.661 1.00 89.13  ? 345 THR A N   1 
ATOM   2652 C CA  . THR A 1 345 ? 145.886 121.483 117.545 1.00 85.13  ? 345 THR A CA  1 
ATOM   2653 C C   . THR A 1 345 ? 144.819 122.538 117.301 1.00 86.94  ? 345 THR A C   1 
ATOM   2654 O O   . THR A 1 345 ? 145.092 123.729 117.478 1.00 84.98  ? 345 THR A O   1 
ATOM   2655 C CB  . THR A 1 345 ? 146.918 121.526 116.421 1.00 83.71  ? 345 THR A CB  1 
ATOM   2656 O OG1 . THR A 1 345 ? 147.420 122.860 116.284 1.00 85.29  ? 345 THR A OG1 1 
ATOM   2657 C CG2 . THR A 1 345 ? 146.288 121.082 115.109 1.00 80.25  ? 345 THR A CG2 1 
ATOM   2658 N N   . GLN A 1 346 ? 143.621 122.134 116.884 1.00 89.65  ? 346 GLN A N   1 
ATOM   2659 C CA  . GLN A 1 346 ? 142.537 123.092 116.708 1.00 83.19  ? 346 GLN A CA  1 
ATOM   2660 C C   . GLN A 1 346 ? 141.919 123.506 118.035 1.00 82.91  ? 346 GLN A C   1 
ATOM   2661 O O   . GLN A 1 346 ? 141.435 124.635 118.160 1.00 88.28  ? 346 GLN A O   1 
ATOM   2662 C CB  . GLN A 1 346 ? 141.465 122.508 115.790 1.00 84.80  ? 346 GLN A CB  1 
ATOM   2663 C CG  . GLN A 1 346 ? 141.977 122.102 114.421 1.00 90.55  ? 346 GLN A CG  1 
ATOM   2664 C CD  . GLN A 1 346 ? 141.450 122.998 113.321 1.00 93.85  ? 346 GLN A CD  1 
ATOM   2665 O OE1 . GLN A 1 346 ? 141.923 124.119 113.139 1.00 94.50  ? 346 GLN A OE1 1 
ATOM   2666 N NE2 . GLN A 1 346 ? 140.460 122.508 112.582 1.00 90.58  ? 346 GLN A NE2 1 
ATOM   2667 N N   . CYS A 1 347 ? 141.916 122.617 119.024 1.00 76.86  ? 347 CYS A N   1 
ATOM   2668 C CA  . CYS A 1 347 ? 141.368 122.948 120.332 1.00 76.01  ? 347 CYS A CA  1 
ATOM   2669 C C   . CYS A 1 347 ? 142.320 123.885 121.060 1.00 79.23  ? 347 CYS A C   1 
ATOM   2670 O O   . CYS A 1 347 ? 143.472 123.528 121.328 1.00 80.99  ? 347 CYS A O   1 
ATOM   2671 C CB  . CYS A 1 347 ? 141.129 121.679 121.146 1.00 74.56  ? 347 CYS A CB  1 
ATOM   2672 S SG  . CYS A 1 347 ? 140.058 120.468 120.337 1.00 80.75  ? 347 CYS A SG  1 
ATOM   2673 N N   . LYS A 1 348 ? 141.839 125.090 121.371 1.00 75.44  ? 348 LYS A N   1 
ATOM   2674 C CA  . LYS A 1 348 ? 142.650 126.116 122.013 1.00 71.04  ? 348 LYS A CA  1 
ATOM   2675 C C   . LYS A 1 348 ? 142.032 126.571 123.326 1.00 78.73  ? 348 LYS A C   1 
ATOM   2676 O O   . LYS A 1 348 ? 142.337 127.659 123.816 1.00 85.17  ? 348 LYS A O   1 
ATOM   2677 C CB  . LYS A 1 348 ? 142.862 127.307 121.082 1.00 66.37  ? 348 LYS A CB  1 
ATOM   2678 C CG  . LYS A 1 348 ? 143.198 126.914 119.660 1.00 75.06  ? 348 LYS A CG  1 
ATOM   2679 C CD  . LYS A 1 348 ? 143.655 128.102 118.844 1.00 80.94  ? 348 LYS A CD  1 
ATOM   2680 C CE  . LYS A 1 348 ? 144.541 127.655 117.697 1.00 82.03  ? 348 LYS A CE  1 
ATOM   2681 N NZ  . LYS A 1 348 ? 145.588 126.702 118.160 1.00 78.30  ? 348 LYS A NZ  1 
ATOM   2682 N N   . ARG A 1 349 ? 141.157 125.754 123.905 1.00 65.84  ? 349 ARG A N   1 
ATOM   2683 C CA  . ARG A 1 349 ? 140.630 126.028 125.234 1.00 54.89  ? 349 ARG A CA  1 
ATOM   2684 C C   . ARG A 1 349 ? 140.391 124.705 125.939 1.00 60.61  ? 349 ARG A C   1 
ATOM   2685 O O   . ARG A 1 349 ? 139.795 123.795 125.359 1.00 66.53  ? 349 ARG A O   1 
ATOM   2686 C CB  . ARG A 1 349 ? 139.336 126.839 125.173 1.00 58.32  ? 349 ARG A CB  1 
ATOM   2687 C CG  . ARG A 1 349 ? 139.096 127.656 126.421 1.00 63.23  ? 349 ARG A CG  1 
ATOM   2688 C CD  . ARG A 1 349 ? 137.669 128.141 126.522 1.00 59.06  ? 349 ARG A CD  1 
ATOM   2689 N NE  . ARG A 1 349 ? 137.160 127.996 127.879 1.00 60.38  ? 349 ARG A NE  1 
ATOM   2690 C CZ  . ARG A 1 349 ? 135.921 128.282 128.245 1.00 62.82  ? 349 ARG A CZ  1 
ATOM   2691 N NH1 . ARG A 1 349 ? 135.038 128.747 127.381 1.00 65.19  ? 349 ARG A NH1 1 
ATOM   2692 N NH2 . ARG A 1 349 ? 135.559 128.097 129.510 1.00 63.42  ? 349 ARG A NH2 1 
ATOM   2693 N N   . VAL A 1 350 ? 140.860 124.601 127.174 1.00 57.93  ? 350 VAL A N   1 
ATOM   2694 C CA  . VAL A 1 350 ? 140.685 123.380 127.949 1.00 57.38  ? 350 VAL A CA  1 
ATOM   2695 C C   . VAL A 1 350 ? 139.254 123.322 128.459 1.00 57.62  ? 350 VAL A C   1 
ATOM   2696 O O   . VAL A 1 350 ? 138.677 124.339 128.860 1.00 61.87  ? 350 VAL A O   1 
ATOM   2697 C CB  . VAL A 1 350 ? 141.709 123.310 129.096 1.00 50.50  ? 350 VAL A CB  1 
ATOM   2698 C CG1 . VAL A 1 350 ? 141.482 124.421 130.099 1.00 48.28  ? 350 VAL A CG1 1 
ATOM   2699 C CG2 . VAL A 1 350 ? 141.662 121.952 129.766 1.00 51.85  ? 350 VAL A CG2 1 
ATOM   2700 N N   . GLY A 1 351 ? 138.663 122.132 128.416 1.00 54.49  ? 351 GLY A N   1 
ATOM   2701 C CA  . GLY A 1 351 ? 137.278 121.988 128.809 1.00 56.39  ? 351 GLY A CA  1 
ATOM   2702 C C   . GLY A 1 351 ? 137.056 122.360 130.260 1.00 50.47  ? 351 GLY A C   1 
ATOM   2703 O O   . GLY A 1 351 ? 137.973 122.373 131.079 1.00 57.22  ? 351 GLY A O   1 
ATOM   2704 N N   . THR A 1 352 ? 135.803 122.681 130.578 1.00 46.46  ? 352 THR A N   1 
ATOM   2705 C CA  . THR A 1 352 ? 135.503 123.172 131.916 1.00 49.76  ? 352 THR A CA  1 
ATOM   2706 C C   . THR A 1 352 ? 135.621 122.075 132.966 1.00 54.46  ? 352 THR A C   1 
ATOM   2707 O O   . THR A 1 352 ? 136.047 122.348 134.092 1.00 65.63  ? 352 THR A O   1 
ATOM   2708 C CB  . THR A 1 352 ? 134.113 123.798 131.949 1.00 54.75  ? 352 THR A CB  1 
ATOM   2709 O OG1 . THR A 1 352 ? 133.917 124.575 130.763 1.00 60.99  ? 352 THR A OG1 1 
ATOM   2710 C CG2 . THR A 1 352 ? 133.985 124.710 133.146 1.00 54.72  ? 352 THR A CG2 1 
ATOM   2711 N N   . GLN A 1 353 ? 135.256 120.837 132.630 1.00 44.87  ? 353 GLN A N   1 
ATOM   2712 C CA  . GLN A 1 353 ? 135.379 119.758 133.605 1.00 41.99  ? 353 GLN A CA  1 
ATOM   2713 C C   . GLN A 1 353 ? 136.838 119.457 133.923 1.00 47.56  ? 353 GLN A C   1 
ATOM   2714 O O   . GLN A 1 353 ? 137.179 119.184 135.078 1.00 47.32  ? 353 GLN A O   1 
ATOM   2715 C CB  . GLN A 1 353 ? 134.670 118.504 133.106 1.00 47.16  ? 353 GLN A CB  1 
ATOM   2716 C CG  . GLN A 1 353 ? 134.999 117.252 133.900 1.00 50.42  ? 353 GLN A CG  1 
ATOM   2717 C CD  . GLN A 1 353 ? 134.275 117.170 135.229 1.00 45.04  ? 353 GLN A CD  1 
ATOM   2718 O OE1 . GLN A 1 353 ? 133.985 118.179 135.861 1.00 33.74  ? 353 GLN A OE1 1 
ATOM   2719 N NE2 . GLN A 1 353 ? 133.983 115.954 135.659 1.00 55.75  ? 353 GLN A NE2 1 
ATOM   2720 N N   . CYS A 1 354 ? 137.713 119.494 132.917 1.00 46.46  ? 354 CYS A N   1 
ATOM   2721 C CA  . CYS A 1 354 ? 139.137 119.304 133.176 1.00 40.05  ? 354 CYS A CA  1 
ATOM   2722 C C   . CYS A 1 354 ? 139.688 120.427 134.041 1.00 44.33  ? 354 CYS A C   1 
ATOM   2723 O O   . CYS A 1 354 ? 140.494 120.189 134.948 1.00 60.82  ? 354 CYS A O   1 
ATOM   2724 C CB  . CYS A 1 354 ? 139.905 119.216 131.861 1.00 44.42  ? 354 CYS A CB  1 
ATOM   2725 S SG  . CYS A 1 354 ? 141.678 119.023 132.060 1.00 62.07  ? 354 CYS A SG  1 
ATOM   2726 N N   . TRP A 1 355 ? 139.259 121.661 133.775 1.00 37.84  ? 355 TRP A N   1 
ATOM   2727 C CA  . TRP A 1 355 ? 139.631 122.784 134.625 1.00 38.54  ? 355 TRP A CA  1 
ATOM   2728 C C   . TRP A 1 355 ? 139.221 122.530 136.068 1.00 41.11  ? 355 TRP A C   1 
ATOM   2729 O O   . TRP A 1 355 ? 140.032 122.668 136.992 1.00 43.54  ? 355 TRP A O   1 
ATOM   2730 C CB  . TRP A 1 355 ? 138.975 124.058 134.095 1.00 39.79  ? 355 TRP A CB  1 
ATOM   2731 C CG  . TRP A 1 355 ? 139.417 125.312 134.762 1.00 46.33  ? 355 TRP A CG  1 
ATOM   2732 C CD1 . TRP A 1 355 ? 140.413 126.137 134.356 1.00 50.76  ? 355 TRP A CD1 1 
ATOM   2733 C CD2 . TRP A 1 355 ? 138.868 125.898 135.948 1.00 50.60  ? 355 TRP A CD2 1 
ATOM   2734 N NE1 . TRP A 1 355 ? 140.527 127.200 135.213 1.00 49.58  ? 355 TRP A NE1 1 
ATOM   2735 C CE2 . TRP A 1 355 ? 139.589 127.074 136.202 1.00 45.28  ? 355 TRP A CE2 1 
ATOM   2736 C CE3 . TRP A 1 355 ? 137.841 125.540 136.822 1.00 51.09  ? 355 TRP A CE3 1 
ATOM   2737 C CZ2 . TRP A 1 355 ? 139.319 127.893 137.290 1.00 46.48  ? 355 TRP A CZ2 1 
ATOM   2738 C CZ3 . TRP A 1 355 ? 137.575 126.355 137.901 1.00 46.53  ? 355 TRP A CZ3 1 
ATOM   2739 C CH2 . TRP A 1 355 ? 138.310 127.516 138.126 1.00 47.06  ? 355 TRP A CH2 1 
ATOM   2740 N N   . VAL A 1 356 ? 137.962 122.140 136.275 1.00 39.59  ? 356 VAL A N   1 
ATOM   2741 C CA  . VAL A 1 356 ? 137.447 121.949 137.626 1.00 35.52  ? 356 VAL A CA  1 
ATOM   2742 C C   . VAL A 1 356 ? 138.175 120.809 138.322 1.00 46.09  ? 356 VAL A C   1 
ATOM   2743 O O   . VAL A 1 356 ? 138.466 120.887 139.519 1.00 58.79  ? 356 VAL A O   1 
ATOM   2744 C CB  . VAL A 1 356 ? 135.927 121.718 137.588 1.00 38.99  ? 356 VAL A CB  1 
ATOM   2745 C CG1 . VAL A 1 356 ? 135.443 121.183 138.910 1.00 37.36  ? 356 VAL A CG1 1 
ATOM   2746 C CG2 . VAL A 1 356 ? 135.217 123.006 137.252 1.00 37.75  ? 356 VAL A CG2 1 
ATOM   2747 N N   . PHE A 1 357 ? 138.483 119.734 137.594 1.00 40.54  ? 357 PHE A N   1 
ATOM   2748 C CA  . PHE A 1 357 ? 139.224 118.635 138.206 1.00 37.63  ? 357 PHE A CA  1 
ATOM   2749 C C   . PHE A 1 357 ? 140.631 119.061 138.600 1.00 41.25  ? 357 PHE A C   1 
ATOM   2750 O O   . PHE A 1 357 ? 141.134 118.652 139.653 1.00 55.70  ? 357 PHE A O   1 
ATOM   2751 C CB  . PHE A 1 357 ? 139.295 117.437 137.274 1.00 36.00  ? 357 PHE A CB  1 
ATOM   2752 C CG  . PHE A 1 357 ? 140.137 116.320 137.809 1.00 40.68  ? 357 PHE A CG  1 
ATOM   2753 C CD1 . PHE A 1 357 ? 139.719 115.581 138.891 1.00 43.67  ? 357 PHE A CD1 1 
ATOM   2754 C CD2 . PHE A 1 357 ? 141.358 116.028 137.250 1.00 50.32  ? 357 PHE A CD2 1 
ATOM   2755 C CE1 . PHE A 1 357 ? 140.483 114.559 139.383 1.00 45.03  ? 357 PHE A CE1 1 
ATOM   2756 C CE2 . PHE A 1 357 ? 142.125 115.009 137.746 1.00 50.36  ? 357 PHE A CE2 1 
ATOM   2757 C CZ  . PHE A 1 357 ? 141.687 114.274 138.811 1.00 42.69  ? 357 PHE A CZ  1 
ATOM   2758 N N   . GLY A 1 358 ? 141.292 119.862 137.766 1.00 30.05  ? 358 GLY A N   1 
ATOM   2759 C CA  . GLY A 1 358 ? 142.595 120.376 138.151 1.00 35.29  ? 358 GLY A CA  1 
ATOM   2760 C C   . GLY A 1 358 ? 142.530 121.220 139.409 1.00 42.82  ? 358 GLY A C   1 
ATOM   2761 O O   . GLY A 1 358 ? 143.361 121.074 140.314 1.00 53.13  ? 358 GLY A O   1 
ATOM   2762 N N   . VAL A 1 359 ? 141.531 122.103 139.492 1.00 37.67  ? 359 VAL A N   1 
ATOM   2763 C CA  . VAL A 1 359 ? 141.385 122.921 140.693 1.00 34.89  ? 359 VAL A CA  1 
ATOM   2764 C C   . VAL A 1 359 ? 141.111 122.044 141.903 1.00 38.91  ? 359 VAL A C   1 
ATOM   2765 O O   . VAL A 1 359 ? 141.629 122.295 142.992 1.00 49.45  ? 359 VAL A O   1 
ATOM   2766 C CB  . VAL A 1 359 ? 140.286 123.983 140.525 1.00 38.73  ? 359 VAL A CB  1 
ATOM   2767 C CG1 . VAL A 1 359 ? 140.401 124.991 141.630 1.00 38.82  ? 359 VAL A CG1 1 
ATOM   2768 C CG2 . VAL A 1 359 ? 140.409 124.686 139.214 1.00 51.86  ? 359 VAL A CG2 1 
ATOM   2769 N N   . ILE A 1 360 ? 140.282 121.013 141.741 1.00 39.24  ? 360 ILE A N   1 
ATOM   2770 C CA  . ILE A 1 360 ? 139.950 120.144 142.865 1.00 37.89  ? 360 ILE A CA  1 
ATOM   2771 C C   . ILE A 1 360 ? 141.194 119.423 143.366 1.00 41.24  ? 360 ILE A C   1 
ATOM   2772 O O   . ILE A 1 360 ? 141.447 119.352 144.574 1.00 55.65  ? 360 ILE A O   1 
ATOM   2773 C CB  . ILE A 1 360 ? 138.847 119.150 142.468 1.00 33.15  ? 360 ILE A CB  1 
ATOM   2774 C CG1 . ILE A 1 360 ? 137.497 119.851 142.423 1.00 36.95  ? 360 ILE A CG1 1 
ATOM   2775 C CG2 . ILE A 1 360 ? 138.788 118.010 143.449 1.00 38.62  ? 360 ILE A CG2 1 
ATOM   2776 C CD1 . ILE A 1 360 ? 136.357 118.928 142.124 1.00 44.84  ? 360 ILE A CD1 1 
ATOM   2777 N N   . GLY A 1 361 ? 141.993 118.882 142.446 1.00 33.89  ? 361 GLY A N   1 
ATOM   2778 C CA  . GLY A 1 361 ? 143.210 118.196 142.856 1.00 29.87  ? 361 GLY A CA  1 
ATOM   2779 C C   . GLY A 1 361 ? 144.172 119.115 143.583 1.00 40.78  ? 361 GLY A C   1 
ATOM   2780 O O   . GLY A 1 361 ? 144.698 118.776 144.650 1.00 54.69  ? 361 GLY A O   1 
ATOM   2781 N N   . PHE A 1 362 ? 144.392 120.310 143.033 1.00 38.24  ? 362 PHE A N   1 
ATOM   2782 C CA  . PHE A 1 362 ? 145.335 121.225 143.664 1.00 37.42  ? 362 PHE A CA  1 
ATOM   2783 C C   . PHE A 1 362 ? 144.813 121.735 145.001 1.00 41.82  ? 362 PHE A C   1 
ATOM   2784 O O   . PHE A 1 362 ? 145.590 121.926 145.941 1.00 50.46  ? 362 PHE A O   1 
ATOM   2785 C CB  . PHE A 1 362 ? 145.651 122.381 142.725 1.00 40.35  ? 362 PHE A CB  1 
ATOM   2786 C CG  . PHE A 1 362 ? 146.708 122.057 141.718 1.00 48.90  ? 362 PHE A CG  1 
ATOM   2787 C CD1 . PHE A 1 362 ? 148.013 121.850 142.116 1.00 48.63  ? 362 PHE A CD1 1 
ATOM   2788 C CD2 . PHE A 1 362 ? 146.398 121.944 140.378 1.00 48.46  ? 362 PHE A CD2 1 
ATOM   2789 C CE1 . PHE A 1 362 ? 148.988 121.548 141.199 1.00 47.49  ? 362 PHE A CE1 1 
ATOM   2790 C CE2 . PHE A 1 362 ? 147.370 121.643 139.456 1.00 49.69  ? 362 PHE A CE2 1 
ATOM   2791 C CZ  . PHE A 1 362 ? 148.668 121.446 139.868 1.00 46.23  ? 362 PHE A CZ  1 
ATOM   2792 N N   . LEU A 1 363 ? 143.502 121.949 145.117 1.00 44.83  ? 363 LEU A N   1 
ATOM   2793 C CA  . LEU A 1 363 ? 142.944 122.424 146.377 1.00 45.90  ? 363 LEU A CA  1 
ATOM   2794 C C   . LEU A 1 363 ? 142.987 121.340 147.442 1.00 48.28  ? 363 LEU A C   1 
ATOM   2795 O O   . LEU A 1 363 ? 143.195 121.635 148.621 1.00 56.79  ? 363 LEU A O   1 
ATOM   2796 C CB  . LEU A 1 363 ? 141.516 122.915 146.170 1.00 41.10  ? 363 LEU A CB  1 
ATOM   2797 C CG  . LEU A 1 363 ? 141.406 124.283 145.508 1.00 45.71  ? 363 LEU A CG  1 
ATOM   2798 C CD1 . LEU A 1 363 ? 139.988 124.780 145.590 1.00 47.74  ? 363 LEU A CD1 1 
ATOM   2799 C CD2 . LEU A 1 363 ? 142.360 125.267 146.151 1.00 41.29  ? 363 LEU A CD2 1 
ATOM   2800 N N   . GLU A 1 364 ? 142.791 120.081 147.055 1.00 41.45  ? 364 GLU A N   1 
ATOM   2801 C CA  . GLU A 1 364 ? 142.976 118.999 148.012 1.00 39.43  ? 364 GLU A CA  1 
ATOM   2802 C C   . GLU A 1 364 ? 144.422 118.937 148.481 1.00 46.97  ? 364 GLU A C   1 
ATOM   2803 O O   . GLU A 1 364 ? 144.692 118.697 149.665 1.00 63.06  ? 364 GLU A O   1 
ATOM   2804 C CB  . GLU A 1 364 ? 142.554 117.670 147.396 1.00 43.30  ? 364 GLU A CB  1 
ATOM   2805 C CG  . GLU A 1 364 ? 141.132 117.271 147.700 1.00 45.01  ? 364 GLU A CG  1 
ATOM   2806 C CD  . GLU A 1 364 ? 140.667 116.117 146.843 1.00 62.48  ? 364 GLU A CD  1 
ATOM   2807 O OE1 . GLU A 1 364 ? 141.358 115.794 145.857 1.00 66.66  ? 364 GLU A OE1 1 
ATOM   2808 O OE2 . GLU A 1 364 ? 139.615 115.525 147.158 1.00 64.23  ? 364 GLU A OE2 1 
ATOM   2809 N N   . ALA A 1 365 ? 145.371 119.156 147.568 1.00 45.37  ? 365 ALA A N   1 
ATOM   2810 C CA  . ALA A 1 365 ? 146.771 119.196 147.980 1.00 48.99  ? 365 ALA A CA  1 
ATOM   2811 C C   . ALA A 1 365 ? 147.030 120.338 148.957 1.00 53.38  ? 365 ALA A C   1 
ATOM   2812 O O   . ALA A 1 365 ? 147.733 120.161 149.959 1.00 60.70  ? 365 ALA A O   1 
ATOM   2813 C CB  . ALA A 1 365 ? 147.678 119.320 146.758 1.00 54.58  ? 365 ALA A CB  1 
ATOM   2814 N N   . ILE A 1 366 ? 146.466 121.516 148.687 1.00 46.46  ? 366 ILE A N   1 
ATOM   2815 C CA  . ILE A 1 366 ? 146.659 122.656 149.582 1.00 46.07  ? 366 ILE A CA  1 
ATOM   2816 C C   . ILE A 1 366 ? 146.036 122.380 150.943 1.00 52.48  ? 366 ILE A C   1 
ATOM   2817 O O   . ILE A 1 366 ? 146.591 122.752 151.981 1.00 62.01  ? 366 ILE A O   1 
ATOM   2818 C CB  . ILE A 1 366 ? 146.090 123.941 148.958 1.00 47.44  ? 366 ILE A CB  1 
ATOM   2819 C CG1 . ILE A 1 366 ? 146.786 124.257 147.643 1.00 51.02  ? 366 ILE A CG1 1 
ATOM   2820 C CG2 . ILE A 1 366 ? 146.268 125.104 149.899 1.00 45.34  ? 366 ILE A CG2 1 
ATOM   2821 C CD1 . ILE A 1 366 ? 146.097 125.333 146.856 1.00 52.30  ? 366 ILE A CD1 1 
ATOM   2822 N N   . VAL A 1 367 ? 144.865 121.744 150.961 1.00 48.27  ? 367 VAL A N   1 
ATOM   2823 C CA  . VAL A 1 367 ? 144.213 121.415 152.225 1.00 46.43  ? 367 VAL A CA  1 
ATOM   2824 C C   . VAL A 1 367 ? 145.078 120.455 153.030 1.00 55.84  ? 367 VAL A C   1 
ATOM   2825 O O   . VAL A 1 367 ? 145.297 120.645 154.234 1.00 65.32  ? 367 VAL A O   1 
ATOM   2826 C CB  . VAL A 1 367 ? 142.811 120.834 151.965 1.00 44.03  ? 367 VAL A CB  1 
ATOM   2827 C CG1 . VAL A 1 367 ? 142.392 119.925 153.098 1.00 48.89  ? 367 VAL A CG1 1 
ATOM   2828 C CG2 . VAL A 1 367 ? 141.805 121.947 151.782 1.00 48.94  ? 367 VAL A CG2 1 
ATOM   2829 N N   . CYS A 1 368 ? 145.597 119.417 152.371 1.00 61.36  ? 368 CYS A N   1 
ATOM   2830 C CA  . CYS A 1 368 ? 146.454 118.460 153.063 1.00 58.43  ? 368 CYS A CA  1 
ATOM   2831 C C   . CYS A 1 368 ? 147.716 119.131 153.589 1.00 65.65  ? 368 CYS A C   1 
ATOM   2832 O O   . CYS A 1 368 ? 148.217 118.771 154.659 1.00 71.52  ? 368 CYS A O   1 
ATOM   2833 C CB  . CYS A 1 368 ? 146.810 117.304 152.132 1.00 56.92  ? 368 CYS A CB  1 
ATOM   2834 S SG  . CYS A 1 368 ? 145.429 116.224 151.743 1.00 81.46  ? 368 CYS A SG  1 
ATOM   2835 N N   . ILE A 1 369 ? 148.251 120.101 152.847 1.00 59.33  ? 369 ILE A N   1 
ATOM   2836 C CA  . ILE A 1 369 ? 149.424 120.829 153.321 1.00 52.01  ? 369 ILE A CA  1 
ATOM   2837 C C   . ILE A 1 369 ? 149.077 121.660 154.549 1.00 58.39  ? 369 ILE A C   1 
ATOM   2838 O O   . ILE A 1 369 ? 149.788 121.633 155.559 1.00 69.65  ? 369 ILE A O   1 
ATOM   2839 C CB  . ILE A 1 369 ? 150.001 121.710 152.200 1.00 44.29  ? 369 ILE A CB  1 
ATOM   2840 C CG1 . ILE A 1 369 ? 150.700 120.857 151.149 1.00 54.94  ? 369 ILE A CG1 1 
ATOM   2841 C CG2 . ILE A 1 369 ? 150.972 122.715 152.771 1.00 53.02  ? 369 ILE A CG2 1 
ATOM   2842 C CD1 . ILE A 1 369 ? 151.254 121.660 150.005 1.00 61.61  ? 369 ILE A CD1 1 
ATOM   2843 N N   . LYS A 1 370 ? 147.978 122.411 154.479 1.00 57.37  ? 370 LYS A N   1 
ATOM   2844 C CA  . LYS A 1 370 ? 147.650 123.356 155.541 1.00 60.95  ? 370 LYS A CA  1 
ATOM   2845 C C   . LYS A 1 370 ? 147.293 122.643 156.837 1.00 62.50  ? 370 LYS A C   1 
ATOM   2846 O O   . LYS A 1 370 ? 147.720 123.063 157.918 1.00 59.13  ? 370 LYS A O   1 
ATOM   2847 C CB  . LYS A 1 370 ? 146.506 124.266 155.095 1.00 55.14  ? 370 LYS A CB  1 
ATOM   2848 C CG  . LYS A 1 370 ? 145.884 125.072 156.214 1.00 55.53  ? 370 LYS A CG  1 
ATOM   2849 C CD  . LYS A 1 370 ? 144.571 125.688 155.781 1.00 57.45  ? 370 LYS A CD  1 
ATOM   2850 C CE  . LYS A 1 370 ? 143.784 126.202 156.970 1.00 55.40  ? 370 LYS A CE  1 
ATOM   2851 N NZ  . LYS A 1 370 ? 144.536 127.228 157.732 1.00 58.07  ? 370 LYS A NZ  1 
ATOM   2852 N N   . PHE A 1 371 ? 146.515 121.567 156.755 1.00 66.24  ? 371 PHE A N   1 
ATOM   2853 C CA  . PHE A 1 371 ? 146.064 120.870 157.951 1.00 64.87  ? 371 PHE A CA  1 
ATOM   2854 C C   . PHE A 1 371 ? 147.001 119.753 158.387 1.00 68.47  ? 371 PHE A C   1 
ATOM   2855 O O   . PHE A 1 371 ? 146.730 119.101 159.399 1.00 71.58  ? 371 PHE A O   1 
ATOM   2856 C CB  . PHE A 1 371 ? 144.665 120.292 157.729 1.00 60.09  ? 371 PHE A CB  1 
ATOM   2857 C CG  . PHE A 1 371 ? 143.599 121.329 157.574 1.00 59.73  ? 371 PHE A CG  1 
ATOM   2858 C CD1 . PHE A 1 371 ? 143.417 122.301 158.534 1.00 56.21  ? 371 PHE A CD1 1 
ATOM   2859 C CD2 . PHE A 1 371 ? 142.776 121.331 156.468 1.00 63.61  ? 371 PHE A CD2 1 
ATOM   2860 C CE1 . PHE A 1 371 ? 142.434 123.252 158.390 1.00 58.48  ? 371 PHE A CE1 1 
ATOM   2861 C CE2 . PHE A 1 371 ? 141.794 122.283 156.322 1.00 61.02  ? 371 PHE A CE2 1 
ATOM   2862 C CZ  . PHE A 1 371 ? 141.624 123.243 157.282 1.00 58.89  ? 371 PHE A CZ  1 
ATOM   2863 N N   . GLY A 1 372 ? 148.087 119.514 157.660 1.00 82.90  ? 372 GLY A N   1 
ATOM   2864 C CA  . GLY A 1 372 ? 148.950 118.380 157.913 1.00 87.67  ? 372 GLY A CA  1 
ATOM   2865 C C   . GLY A 1 372 ? 150.256 118.660 158.617 1.00 87.48  ? 372 GLY A C   1 
ATOM   2866 O O   . GLY A 1 372 ? 151.078 117.745 158.740 1.00 89.67  ? 372 GLY A O   1 
ATOM   2867 N N   . GLN A 1 373 ? 150.479 119.883 159.095 1.00 91.08  ? 373 GLN A N   1 
ATOM   2868 C CA  . GLN A 1 373 ? 151.756 120.200 159.720 1.00 96.04  ? 373 GLN A CA  1 
ATOM   2869 C C   . GLN A 1 373 ? 151.949 119.492 161.054 1.00 98.93  ? 373 GLN A C   1 
ATOM   2870 O O   . GLN A 1 373 ? 153.074 119.452 161.561 1.00 101.06 ? 373 GLN A O   1 
ATOM   2871 C CB  . GLN A 1 373 ? 151.886 121.711 159.900 1.00 94.65  ? 373 GLN A CB  1 
ATOM   2872 C CG  . GLN A 1 373 ? 152.508 122.405 158.707 1.00 95.77  ? 373 GLN A CG  1 
ATOM   2873 C CD  . GLN A 1 373 ? 151.762 123.657 158.315 1.00 98.26  ? 373 GLN A CD  1 
ATOM   2874 O OE1 . GLN A 1 373 ? 150.903 124.136 159.053 1.00 101.44 ? 373 GLN A OE1 1 
ATOM   2875 N NE2 . GLN A 1 373 ? 152.080 124.192 157.142 1.00 93.14  ? 373 GLN A NE2 1 
ATOM   2876 N N   . ASP A 1 374 ? 150.885 118.936 161.636 1.00 102.76 ? 374 ASP A N   1 
ATOM   2877 C CA  . ASP A 1 374 ? 151.028 118.259 162.920 1.00 105.10 ? 374 ASP A CA  1 
ATOM   2878 C C   . ASP A 1 374 ? 151.729 116.914 162.767 1.00 106.64 ? 374 ASP A C   1 
ATOM   2879 O O   . ASP A 1 374 ? 152.586 116.559 163.585 1.00 105.55 ? 374 ASP A O   1 
ATOM   2880 C CB  . ASP A 1 374 ? 149.659 118.089 163.580 1.00 104.59 ? 374 ASP A CB  1 
ATOM   2881 C CG  . ASP A 1 374 ? 148.670 117.350 162.699 1.00 106.09 ? 374 ASP A CG  1 
ATOM   2882 O OD1 . ASP A 1 374 ? 148.895 116.155 162.415 1.00 107.78 ? 374 ASP A OD1 1 
ATOM   2883 O OD2 . ASP A 1 374 ? 147.666 117.967 162.290 1.00 102.47 ? 374 ASP A OD2 1 
ATOM   2884 N N   . LEU A 1 375 ? 151.381 116.150 161.730 1.00 103.53 ? 375 LEU A N   1 
ATOM   2885 C CA  . LEU A 1 375 ? 152.000 114.844 161.536 1.00 103.31 ? 375 LEU A CA  1 
ATOM   2886 C C   . LEU A 1 375 ? 153.408 114.953 160.965 1.00 102.76 ? 375 LEU A C   1 
ATOM   2887 O O   . LEU A 1 375 ? 154.244 114.080 161.225 1.00 102.34 ? 375 LEU A O   1 
ATOM   2888 C CB  . LEU A 1 375 ? 151.120 113.975 160.634 1.00 103.79 ? 375 LEU A CB  1 
ATOM   2889 C CG  . LEU A 1 375 ? 150.987 114.345 159.157 1.00 99.38  ? 375 LEU A CG  1 
ATOM   2890 C CD1 . LEU A 1 375 ? 151.828 113.427 158.297 1.00 99.04  ? 375 LEU A CD1 1 
ATOM   2891 C CD2 . LEU A 1 375 ? 149.538 114.278 158.734 1.00 98.74  ? 375 LEU A CD2 1 
ATOM   2892 N N   . PHE A 1 376 ? 153.689 115.999 160.194 1.00 108.17 ? 376 PHE A N   1 
ATOM   2893 C CA  . PHE A 1 376 ? 155.028 116.196 159.659 1.00 112.29 ? 376 PHE A CA  1 
ATOM   2894 C C   . PHE A 1 376 ? 156.007 116.561 160.769 1.00 112.73 ? 376 PHE A C   1 
ATOM   2895 O O   . PHE A 1 376 ? 155.735 117.435 161.596 1.00 110.72 ? 376 PHE A O   1 
ATOM   2896 C CB  . PHE A 1 376 ? 155.025 117.299 158.599 1.00 113.07 ? 376 PHE A CB  1 
ATOM   2897 C CG  . PHE A 1 376 ? 154.186 116.992 157.385 1.00 116.25 ? 376 PHE A CG  1 
ATOM   2898 C CD1 . PHE A 1 376 ? 154.120 115.707 156.873 1.00 113.37 ? 376 PHE A CD1 1 
ATOM   2899 C CD2 . PHE A 1 376 ? 153.498 118.006 156.730 1.00 113.43 ? 376 PHE A CD2 1 
ATOM   2900 C CE1 . PHE A 1 376 ? 153.357 115.435 155.749 1.00 115.64 ? 376 PHE A CE1 1 
ATOM   2901 C CE2 . PHE A 1 376 ? 152.737 117.740 155.606 1.00 108.36 ? 376 PHE A CE2 1 
ATOM   2902 C CZ  . PHE A 1 376 ? 152.666 116.455 155.115 1.00 111.04 ? 376 PHE A CZ  1 
ATOM   2903 N N   . SER A 1 377 ? 157.153 115.879 160.790 1.00 112.93 ? 377 SER A N   1 
ATOM   2904 C CA  . SER A 1 377 ? 158.217 116.198 161.736 1.00 108.83 ? 377 SER A CA  1 
ATOM   2905 C C   . SER A 1 377 ? 159.507 116.612 161.041 1.00 109.61 ? 377 SER A C   1 
ATOM   2906 O O   . SER A 1 377 ? 159.997 117.723 161.270 1.00 105.73 ? 377 SER A O   1 
ATOM   2907 C CB  . SER A 1 377 ? 158.462 114.998 162.659 1.00 107.67 ? 377 SER A CB  1 
ATOM   2908 O OG  . SER A 1 377 ? 158.568 113.797 161.914 1.00 110.40 ? 377 SER A OG  1 
ATOM   2909 N N   . LYS A 1 378 ? 160.071 115.756 160.195 1.00 108.38 ? 378 LYS A N   1 
ATOM   2910 C CA  . LYS A 1 378 ? 161.353 116.001 159.535 1.00 104.26 ? 378 LYS A CA  1 
ATOM   2911 C C   . LYS A 1 378 ? 161.198 115.623 158.058 1.00 103.26 ? 378 LYS A C   1 
ATOM   2912 O O   . LYS A 1 378 ? 161.899 114.769 157.516 1.00 99.41  ? 378 LYS A O   1 
ATOM   2913 C CB  . LYS A 1 378 ? 162.475 115.271 160.290 1.00 102.35 ? 378 LYS A CB  1 
ATOM   2914 C CG  . LYS A 1 378 ? 163.771 114.945 159.549 1.00 102.69 ? 378 LYS A CG  1 
ATOM   2915 C CD  . LYS A 1 378 ? 164.636 113.983 160.343 1.00 103.58 ? 378 LYS A CD  1 
ATOM   2916 C CE  . LYS A 1 378 ? 165.566 114.730 161.283 1.00 102.73 ? 378 LYS A CE  1 
ATOM   2917 N NZ  . LYS A 1 378 ? 166.113 113.841 162.344 1.00 103.03 ? 378 LYS A NZ  1 
ATOM   2918 N N   . THR A 1 379 ? 160.177 116.201 157.425 1.00 100.00 ? 379 THR A N   1 
ATOM   2919 C CA  . THR A 1 379 ? 159.810 115.862 156.054 1.00 97.53  ? 379 THR A CA  1 
ATOM   2920 C C   . THR A 1 379 ? 161.018 115.823 155.129 1.00 98.14  ? 379 THR A C   1 
ATOM   2921 O O   . THR A 1 379 ? 161.692 116.835 154.918 1.00 94.61  ? 379 THR A O   1 
ATOM   2922 C CB  . THR A 1 379 ? 158.805 116.876 155.515 1.00 93.76  ? 379 THR A CB  1 
ATOM   2923 O OG1 . THR A 1 379 ? 159.481 118.104 155.220 1.00 94.90  ? 379 THR A OG1 1 
ATOM   2924 C CG2 . THR A 1 379 ? 157.737 117.146 156.534 1.00 88.47  ? 379 THR A CG2 1 
ATOM   2925 N N   . GLN A 1 380 ? 161.284 114.643 154.574 1.00 96.51  ? 380 GLN A N   1 
ATOM   2926 C CA  . GLN A 1 380 ? 162.210 114.501 153.459 1.00 92.59  ? 380 GLN A CA  1 
ATOM   2927 C C   . GLN A 1 380 ? 161.407 114.621 152.171 1.00 96.77  ? 380 GLN A C   1 
ATOM   2928 O O   . GLN A 1 380 ? 160.694 113.690 151.783 1.00 95.15  ? 380 GLN A O   1 
ATOM   2929 C CB  . GLN A 1 380 ? 162.962 113.174 153.524 1.00 87.87  ? 380 GLN A CB  1 
ATOM   2930 C CG  . GLN A 1 380 ? 163.870 113.033 154.731 1.00 93.52  ? 380 GLN A CG  1 
ATOM   2931 C CD  . GLN A 1 380 ? 163.493 111.868 155.618 1.00 97.64  ? 380 GLN A CD  1 
ATOM   2932 O OE1 . GLN A 1 380 ? 162.368 111.373 155.566 1.00 101.58 ? 380 GLN A OE1 1 
ATOM   2933 N NE2 . GLN A 1 380 ? 164.435 111.419 156.437 1.00 91.87  ? 380 GLN A NE2 1 
ATOM   2934 N N   . ILE A 1 381 ? 161.508 115.779 151.525 1.00 87.55  ? 381 ILE A N   1 
ATOM   2935 C CA  . ILE A 1 381 ? 160.875 116.030 150.238 1.00 76.95  ? 381 ILE A CA  1 
ATOM   2936 C C   . ILE A 1 381 ? 161.821 115.462 149.188 1.00 77.39  ? 381 ILE A C   1 
ATOM   2937 O O   . ILE A 1 381 ? 161.496 115.386 147.999 1.00 82.28  ? 381 ILE A O   1 
ATOM   2938 C CB  . ILE A 1 381 ? 160.597 117.536 150.059 1.00 79.05  ? 381 ILE A CB  1 
ATOM   2939 C CG1 . ILE A 1 381 ? 160.203 117.891 148.628 1.00 77.97  ? 381 ILE A CG1 1 
ATOM   2940 C CG2 . ILE A 1 381 ? 161.810 118.346 150.467 1.00 84.36  ? 381 ILE A CG2 1 
ATOM   2941 C CD1 . ILE A 1 381 ? 159.323 119.107 148.536 1.00 80.80  ? 381 ILE A CD1 1 
ATOM   2942 N N   . LEU A 1 382 ? 162.997 115.021 149.644 1.00 80.94  ? 382 LEU A N   1 
ATOM   2943 C CA  . LEU A 1 382 ? 163.956 114.383 148.752 1.00 79.03  ? 382 LEU A CA  1 
ATOM   2944 C C   . LEU A 1 382 ? 163.342 113.187 148.037 1.00 81.48  ? 382 LEU A C   1 
ATOM   2945 O O   . LEU A 1 382 ? 163.694 112.908 146.887 1.00 86.56  ? 382 LEU A O   1 
ATOM   2946 C CB  . LEU A 1 382 ? 165.194 113.954 149.537 1.00 81.23  ? 382 LEU A CB  1 
ATOM   2947 C CG  . LEU A 1 382 ? 166.161 115.061 149.966 1.00 85.28  ? 382 LEU A CG  1 
ATOM   2948 C CD1 . LEU A 1 382 ? 166.299 116.126 148.889 1.00 84.59  ? 382 LEU A CD1 1 
ATOM   2949 C CD2 . LEU A 1 382 ? 165.739 115.677 151.292 1.00 81.64  ? 382 LEU A CD2 1 
ATOM   2950 N N   . TYR A 1 383 ? 162.434 112.464 148.695 1.00 76.69  ? 383 TYR A N   1 
ATOM   2951 C CA  . TYR A 1 383 ? 161.660 111.460 147.975 1.00 72.34  ? 383 TYR A CA  1 
ATOM   2952 C C   . TYR A 1 383 ? 160.542 112.097 147.165 1.00 71.52  ? 383 TYR A C   1 
ATOM   2953 O O   . TYR A 1 383 ? 160.174 111.585 146.105 1.00 76.78  ? 383 TYR A O   1 
ATOM   2954 C CB  . TYR A 1 383 ? 161.079 110.427 148.932 1.00 71.72  ? 383 TYR A CB  1 
ATOM   2955 C CG  . TYR A 1 383 ? 160.463 109.245 148.220 1.00 70.72  ? 383 TYR A CG  1 
ATOM   2956 C CD1 . TYR A 1 383 ? 161.239 108.168 147.815 1.00 71.03  ? 383 TYR A CD1 1 
ATOM   2957 C CD2 . TYR A 1 383 ? 159.110 109.220 147.930 1.00 70.07  ? 383 TYR A CD2 1 
ATOM   2958 C CE1 . TYR A 1 383 ? 160.680 107.093 147.163 1.00 69.73  ? 383 TYR A CE1 1 
ATOM   2959 C CE2 . TYR A 1 383 ? 158.544 108.154 147.277 1.00 73.05  ? 383 TYR A CE2 1 
ATOM   2960 C CZ  . TYR A 1 383 ? 159.333 107.094 146.895 1.00 72.68  ? 383 TYR A CZ  1 
ATOM   2961 O OH  . TYR A 1 383 ? 158.761 106.031 146.243 1.00 73.11  ? 383 TYR A OH  1 
ATOM   2962 N N   . VAL A 1 384 ? 159.967 113.196 147.652 1.00 79.70  ? 384 VAL A N   1 
ATOM   2963 C CA  . VAL A 1 384 ? 158.945 113.866 146.860 1.00 78.44  ? 384 VAL A CA  1 
ATOM   2964 C C   . VAL A 1 384 ? 159.550 114.416 145.574 1.00 76.39  ? 384 VAL A C   1 
ATOM   2965 O O   . VAL A 1 384 ? 158.911 114.395 144.518 1.00 72.51  ? 384 VAL A O   1 
ATOM   2966 C CB  . VAL A 1 384 ? 158.232 114.956 147.683 1.00 85.39  ? 384 VAL A CB  1 
ATOM   2967 C CG1 . VAL A 1 384 ? 157.480 115.908 146.776 1.00 81.05  ? 384 VAL A CG1 1 
ATOM   2968 C CG2 . VAL A 1 384 ? 157.255 114.326 148.662 1.00 84.54  ? 384 VAL A CG2 1 
ATOM   2969 N N   . VAL A 1 385 ? 160.789 114.899 145.625 1.00 85.94  ? 385 VAL A N   1 
ATOM   2970 C CA  . VAL A 1 385 ? 161.471 115.227 144.380 1.00 80.47  ? 385 VAL A CA  1 
ATOM   2971 C C   . VAL A 1 385 ? 161.737 113.961 143.580 1.00 78.89  ? 385 VAL A C   1 
ATOM   2972 O O   . VAL A 1 385 ? 161.779 113.992 142.345 1.00 88.73  ? 385 VAL A O   1 
ATOM   2973 C CB  . VAL A 1 385 ? 162.767 116.005 144.678 1.00 82.27  ? 385 VAL A CB  1 
ATOM   2974 C CG1 . VAL A 1 385 ? 163.690 116.031 143.467 1.00 79.75  ? 385 VAL A CG1 1 
ATOM   2975 C CG2 . VAL A 1 385 ? 162.439 117.418 145.132 1.00 82.10  ? 385 VAL A CG2 1 
ATOM   2976 N N   . LEU A 1 386 ? 161.885 112.824 144.261 1.00 78.01  ? 386 LEU A N   1 
ATOM   2977 C CA  . LEU A 1 386 ? 162.451 111.646 143.617 1.00 80.30  ? 386 LEU A CA  1 
ATOM   2978 C C   . LEU A 1 386 ? 161.544 111.097 142.521 1.00 83.56  ? 386 LEU A C   1 
ATOM   2979 O O   . LEU A 1 386 ? 162.040 110.744 141.445 1.00 84.77  ? 386 LEU A O   1 
ATOM   2980 C CB  . LEU A 1 386 ? 162.785 110.579 144.664 1.00 86.00  ? 386 LEU A CB  1 
ATOM   2981 C CG  . LEU A 1 386 ? 163.389 109.219 144.293 1.00 88.97  ? 386 LEU A CG  1 
ATOM   2982 C CD1 . LEU A 1 386 ? 164.031 108.609 145.523 1.00 88.18  ? 386 LEU A CD1 1 
ATOM   2983 C CD2 . LEU A 1 386 ? 162.362 108.246 143.743 1.00 80.00  ? 386 LEU A CD2 1 
ATOM   2984 N N   . TRP A 1 387 ? 160.219 110.998 142.741 1.00 79.66  ? 387 TRP A N   1 
ATOM   2985 C CA  . TRP A 1 387 ? 159.497 110.406 141.619 1.00 81.75  ? 387 TRP A CA  1 
ATOM   2986 C C   . TRP A 1 387 ? 159.297 111.403 140.492 1.00 86.38  ? 387 TRP A C   1 
ATOM   2987 O O   . TRP A 1 387 ? 158.962 110.994 139.377 1.00 91.62  ? 387 TRP A O   1 
ATOM   2988 C CB  . TRP A 1 387 ? 158.104 109.826 141.915 1.00 78.93  ? 387 TRP A CB  1 
ATOM   2989 C CG  . TRP A 1 387 ? 156.921 110.775 142.020 1.00 84.93  ? 387 TRP A CG  1 
ATOM   2990 C CD1 . TRP A 1 387 ? 155.846 110.761 141.185 1.00 89.98  ? 387 TRP A CD1 1 
ATOM   2991 C CD2 . TRP A 1 387 ? 156.537 111.630 143.111 1.00 93.45  ? 387 TRP A CD2 1 
ATOM   2992 N NE1 . TRP A 1 387 ? 154.910 111.670 141.574 1.00 86.38  ? 387 TRP A NE1 1 
ATOM   2993 C CE2 . TRP A 1 387 ? 155.291 112.204 142.771 1.00 88.42  ? 387 TRP A CE2 1 
ATOM   2994 C CE3 . TRP A 1 387 ? 157.143 112.019 144.302 1.00 99.12  ? 387 TRP A CE3 1 
ATOM   2995 C CZ2 . TRP A 1 387 ? 154.645 113.139 143.574 1.00 84.90  ? 387 TRP A CZ2 1 
ATOM   2996 C CZ3 . TRP A 1 387 ? 156.482 112.949 145.105 1.00 93.43  ? 387 TRP A CZ3 1 
ATOM   2997 C CH2 . TRP A 1 387 ? 155.259 113.500 144.733 1.00 93.49  ? 387 TRP A CH2 1 
ATOM   2998 N N   . LEU A 1 388 ? 159.490 112.696 140.751 1.00 71.86  ? 388 LEU A N   1 
ATOM   2999 C CA  . LEU A 1 388 ? 159.366 113.675 139.680 1.00 67.78  ? 388 LEU A CA  1 
ATOM   3000 C C   . LEU A 1 388 ? 160.402 113.415 138.597 1.00 74.62  ? 388 LEU A C   1 
ATOM   3001 O O   . LEU A 1 388 ? 160.107 113.533 137.403 1.00 85.04  ? 388 LEU A O   1 
ATOM   3002 C CB  . LEU A 1 388 ? 159.508 115.091 140.233 1.00 75.38  ? 388 LEU A CB  1 
ATOM   3003 C CG  . LEU A 1 388 ? 158.549 115.573 141.328 1.00 84.28  ? 388 LEU A CG  1 
ATOM   3004 C CD1 . LEU A 1 388 ? 158.343 117.078 141.220 1.00 84.02  ? 388 LEU A CD1 1 
ATOM   3005 C CD2 . LEU A 1 388 ? 157.211 114.846 141.304 1.00 78.47  ? 388 LEU A CD2 1 
ATOM   3006 N N   . LEU A 1 389 ? 161.624 113.060 138.994 1.00 72.37  ? 389 LEU A N   1 
ATOM   3007 C CA  . LEU A 1 389 ? 162.622 112.647 138.014 1.00 74.92  ? 389 LEU A CA  1 
ATOM   3008 C C   . LEU A 1 389 ? 162.349 111.235 137.508 1.00 79.15  ? 389 LEU A C   1 
ATOM   3009 O O   . LEU A 1 389 ? 162.529 110.953 136.319 1.00 84.07  ? 389 LEU A O   1 
ATOM   3010 C CB  . LEU A 1 389 ? 164.023 112.742 138.614 1.00 74.82  ? 389 LEU A CB  1 
ATOM   3011 C CG  . LEU A 1 389 ? 165.173 112.832 137.609 1.00 78.54  ? 389 LEU A CG  1 
ATOM   3012 C CD1 . LEU A 1 389 ? 166.142 113.928 138.006 1.00 79.52  ? 389 LEU A CD1 1 
ATOM   3013 C CD2 . LEU A 1 389 ? 165.897 111.502 137.486 1.00 79.94  ? 389 LEU A CD2 1 
ATOM   3014 N N   . CYS A 1 390 ? 161.907 110.336 138.392 1.00 77.16  ? 390 CYS A N   1 
ATOM   3015 C CA  . CYS A 1 390 ? 161.658 108.958 137.980 1.00 75.94  ? 390 CYS A CA  1 
ATOM   3016 C C   . CYS A 1 390 ? 160.508 108.861 136.989 1.00 82.23  ? 390 CYS A C   1 
ATOM   3017 O O   . CYS A 1 390 ? 160.523 107.992 136.111 1.00 88.09  ? 390 CYS A O   1 
ATOM   3018 C CB  . CYS A 1 390 ? 161.384 108.083 139.199 1.00 80.17  ? 390 CYS A CB  1 
ATOM   3019 S SG  . CYS A 1 390 ? 162.854 107.712 140.172 1.00 101.27 ? 390 CYS A SG  1 
ATOM   3020 N N   . VAL A 1 391 ? 159.499 109.723 137.116 1.00 72.73  ? 391 VAL A N   1 
ATOM   3021 C CA  . VAL A 1 391 ? 158.461 109.793 136.094 1.00 72.30  ? 391 VAL A CA  1 
ATOM   3022 C C   . VAL A 1 391 ? 159.020 110.399 134.812 1.00 70.71  ? 391 VAL A C   1 
ATOM   3023 O O   . VAL A 1 391 ? 158.712 109.942 133.706 1.00 71.59  ? 391 VAL A O   1 
ATOM   3024 C CB  . VAL A 1 391 ? 157.245 110.576 136.620 1.00 68.43  ? 391 VAL A CB  1 
ATOM   3025 C CG1 . VAL A 1 391 ? 156.304 110.916 135.491 1.00 70.96  ? 391 VAL A CG1 1 
ATOM   3026 C CG2 . VAL A 1 391 ? 156.517 109.766 137.669 1.00 63.35  ? 391 VAL A CG2 1 
ATOM   3027 N N   . ALA A 1 392 ? 159.862 111.428 134.938 1.00 70.75  ? 392 ALA A N   1 
ATOM   3028 C CA  . ALA A 1 392 ? 160.464 112.041 133.758 1.00 67.63  ? 392 ALA A CA  1 
ATOM   3029 C C   . ALA A 1 392 ? 161.378 111.066 133.032 1.00 73.01  ? 392 ALA A C   1 
ATOM   3030 O O   . ALA A 1 392 ? 161.424 111.049 131.798 1.00 80.47  ? 392 ALA A O   1 
ATOM   3031 C CB  . ALA A 1 392 ? 161.234 113.301 134.150 1.00 65.78  ? 392 ALA A CB  1 
ATOM   3032 N N   . PHE A 1 393 ? 162.131 110.258 133.780 1.00 84.09  ? 393 PHE A N   1 
ATOM   3033 C CA  . PHE A 1 393 ? 162.980 109.254 133.150 1.00 84.74  ? 393 PHE A CA  1 
ATOM   3034 C C   . PHE A 1 393 ? 162.143 108.207 132.429 1.00 81.69  ? 393 PHE A C   1 
ATOM   3035 O O   . PHE A 1 393 ? 162.503 107.759 131.336 1.00 84.61  ? 393 PHE A O   1 
ATOM   3036 C CB  . PHE A 1 393 ? 163.883 108.601 134.197 1.00 85.58  ? 393 PHE A CB  1 
ATOM   3037 C CG  . PHE A 1 393 ? 164.127 107.134 133.967 1.00 90.22  ? 393 PHE A CG  1 
ATOM   3038 C CD1 . PHE A 1 393 ? 164.959 106.705 132.945 1.00 87.38  ? 393 PHE A CD1 1 
ATOM   3039 C CD2 . PHE A 1 393 ? 163.522 106.183 134.772 1.00 90.84  ? 393 PHE A CD2 1 
ATOM   3040 C CE1 . PHE A 1 393 ? 165.185 105.357 132.735 1.00 86.45  ? 393 PHE A CE1 1 
ATOM   3041 C CE2 . PHE A 1 393 ? 163.743 104.832 134.565 1.00 88.54  ? 393 PHE A CE2 1 
ATOM   3042 C CZ  . PHE A 1 393 ? 164.575 104.420 133.545 1.00 87.32  ? 393 PHE A CZ  1 
ATOM   3043 N N   . THR A 1 394 ? 161.021 107.803 133.025 1.00 76.55  ? 394 THR A N   1 
ATOM   3044 C CA  . THR A 1 394 ? 160.201 106.764 132.416 1.00 83.23  ? 394 THR A CA  1 
ATOM   3045 C C   . THR A 1 394 ? 159.423 107.286 131.213 1.00 87.06  ? 394 THR A C   1 
ATOM   3046 O O   . THR A 1 394 ? 159.305 106.587 130.201 1.00 89.49  ? 394 THR A O   1 
ATOM   3047 C CB  . THR A 1 394 ? 159.247 106.169 133.451 1.00 84.83  ? 394 THR A CB  1 
ATOM   3048 O OG1 . THR A 1 394 ? 159.948 105.960 134.682 1.00 85.51  ? 394 THR A OG1 1 
ATOM   3049 C CG2 . THR A 1 394 ? 158.715 104.837 132.963 1.00 82.61  ? 394 THR A CG2 1 
ATOM   3050 N N   . THR A 1 395 ? 158.888 108.508 131.294 1.00 82.77  ? 395 THR A N   1 
ATOM   3051 C CA  . THR A 1 395 ? 158.213 109.083 130.135 1.00 79.84  ? 395 THR A CA  1 
ATOM   3052 C C   . THR A 1 395 ? 159.197 109.458 129.038 1.00 79.94  ? 395 THR A C   1 
ATOM   3053 O O   . THR A 1 395 ? 158.774 109.740 127.914 1.00 86.25  ? 395 THR A O   1 
ATOM   3054 C CB  . THR A 1 395 ? 157.393 110.311 130.532 1.00 81.72  ? 395 THR A CB  1 
ATOM   3055 O OG1 . THR A 1 395 ? 156.539 110.688 129.446 1.00 79.47  ? 395 THR A OG1 1 
ATOM   3056 C CG2 . THR A 1 395 ? 158.301 111.475 130.843 1.00 83.54  ? 395 THR A CG2 1 
ATOM   3057 N N   . PHE A 1 396 ? 160.493 109.483 129.342 1.00 86.24  ? 396 PHE A N   1 
ATOM   3058 C CA  . PHE A 1 396 ? 161.501 109.642 128.303 1.00 86.86  ? 396 PHE A CA  1 
ATOM   3059 C C   . PHE A 1 396 ? 161.850 108.304 127.664 1.00 88.84  ? 396 PHE A C   1 
ATOM   3060 O O   . PHE A 1 396 ? 162.136 108.244 126.464 1.00 94.48  ? 396 PHE A O   1 
ATOM   3061 C CB  . PHE A 1 396 ? 162.751 110.305 128.880 1.00 85.70  ? 396 PHE A CB  1 
ATOM   3062 C CG  . PHE A 1 396 ? 163.840 110.522 127.873 1.00 89.18  ? 396 PHE A CG  1 
ATOM   3063 C CD1 . PHE A 1 396 ? 163.844 111.650 127.072 1.00 89.78  ? 396 PHE A CD1 1 
ATOM   3064 C CD2 . PHE A 1 396 ? 164.866 109.603 127.735 1.00 90.21  ? 396 PHE A CD2 1 
ATOM   3065 C CE1 . PHE A 1 396 ? 164.846 111.853 126.147 1.00 90.56  ? 396 PHE A CE1 1 
ATOM   3066 C CE2 . PHE A 1 396 ? 165.869 109.800 126.812 1.00 90.60  ? 396 PHE A CE2 1 
ATOM   3067 C CZ  . PHE A 1 396 ? 165.861 110.926 126.017 1.00 91.09  ? 396 PHE A CZ  1 
ATOM   3068 N N   . LEU A 1 397 ? 161.841 107.225 128.448 1.00 88.23  ? 397 LEU A N   1 
ATOM   3069 C CA  . LEU A 1 397 ? 162.045 105.902 127.870 1.00 88.79  ? 397 LEU A CA  1 
ATOM   3070 C C   . LEU A 1 397 ? 160.838 105.470 127.051 1.00 89.43  ? 397 LEU A C   1 
ATOM   3071 O O   . LEU A 1 397 ? 160.972 104.685 126.106 1.00 95.72  ? 397 LEU A O   1 
ATOM   3072 C CB  . LEU A 1 397 ? 162.339 104.877 128.965 1.00 97.31  ? 397 LEU A CB  1 
ATOM   3073 C CG  . LEU A 1 397 ? 163.804 104.551 129.279 1.00 100.22 ? 397 LEU A CG  1 
ATOM   3074 C CD1 . LEU A 1 397 ? 163.892 103.332 130.185 1.00 95.12  ? 397 LEU A CD1 1 
ATOM   3075 C CD2 . LEU A 1 397 ? 164.610 104.332 128.007 1.00 93.32  ? 397 LEU A CD2 1 
ATOM   3076 N N   . CYS A 1 398 ? 159.649 105.964 127.401 1.00 87.16  ? 398 CYS A N   1 
ATOM   3077 C CA  . CYS A 1 398 ? 158.467 105.666 126.600 1.00 91.57  ? 398 CYS A CA  1 
ATOM   3078 C C   . CYS A 1 398 ? 158.625 106.194 125.181 1.00 93.20  ? 398 CYS A C   1 
ATOM   3079 O O   . CYS A 1 398 ? 158.191 105.552 124.219 1.00 97.69  ? 398 CYS A O   1 
ATOM   3080 C CB  . CYS A 1 398 ? 157.220 106.257 127.255 1.00 93.57  ? 398 CYS A CB  1 
ATOM   3081 S SG  . CYS A 1 398 ? 156.423 105.188 128.475 1.00 101.71 ? 398 CYS A SG  1 
ATOM   3082 N N   . LEU A 1 399 ? 159.238 107.368 125.031 1.00 97.75  ? 399 LEU A N   1 
ATOM   3083 C CA  . LEU A 1 399 ? 159.507 107.899 123.701 1.00 97.74  ? 399 LEU A CA  1 
ATOM   3084 C C   . LEU A 1 399 ? 160.446 106.980 122.932 1.00 101.37 ? 399 LEU A C   1 
ATOM   3085 O O   . LEU A 1 399 ? 160.128 106.526 121.828 1.00 103.67 ? 399 LEU A O   1 
ATOM   3086 C CB  . LEU A 1 399 ? 160.103 109.302 123.809 1.00 97.02  ? 399 LEU A CB  1 
ATOM   3087 C CG  . LEU A 1 399 ? 159.202 110.471 123.424 1.00 97.69  ? 399 LEU A CG  1 
ATOM   3088 C CD1 . LEU A 1 399 ? 158.171 110.720 124.507 1.00 94.19  ? 399 LEU A CD1 1 
ATOM   3089 C CD2 . LEU A 1 399 ? 160.034 111.713 123.165 1.00 100.13 ? 399 LEU A CD2 1 
ATOM   3090 N N   . TYR A 1 400 ? 161.609 106.682 123.514 1.00 118.14 ? 400 TYR A N   1 
ATOM   3091 C CA  . TYR A 1 400 ? 162.570 105.815 122.841 1.00 117.54 ? 400 TYR A CA  1 
ATOM   3092 C C   . TYR A 1 400 ? 162.005 104.417 122.639 1.00 117.65 ? 400 TYR A C   1 
ATOM   3093 O O   . TYR A 1 400 ? 162.199 103.808 121.581 1.00 122.48 ? 400 TYR A O   1 
ATOM   3094 C CB  . TYR A 1 400 ? 163.872 105.747 123.633 1.00 118.79 ? 400 TYR A CB  1 
ATOM   3095 C CG  . TYR A 1 400 ? 164.646 104.474 123.388 1.00 120.73 ? 400 TYR A CG  1 
ATOM   3096 C CD1 . TYR A 1 400 ? 165.452 104.337 122.267 1.00 122.38 ? 400 TYR A CD1 1 
ATOM   3097 C CD2 . TYR A 1 400 ? 164.567 103.407 124.273 1.00 119.43 ? 400 TYR A CD2 1 
ATOM   3098 C CE1 . TYR A 1 400 ? 166.158 103.175 122.034 1.00 123.37 ? 400 TYR A CE1 1 
ATOM   3099 C CE2 . TYR A 1 400 ? 165.268 102.241 124.048 1.00 119.83 ? 400 TYR A CE2 1 
ATOM   3100 C CZ  . TYR A 1 400 ? 166.063 102.130 122.929 1.00 121.80 ? 400 TYR A CZ  1 
ATOM   3101 O OH  . TYR A 1 400 ? 166.765 100.969 122.703 1.00 120.62 ? 400 TYR A OH  1 
ATOM   3102 N N   . GLY A 1 401 ? 161.306 103.890 123.644 1.00 117.45 ? 401 GLY A N   1 
ATOM   3103 C CA  . GLY A 1 401 ? 160.721 102.568 123.512 1.00 120.94 ? 401 GLY A CA  1 
ATOM   3104 C C   . GLY A 1 401 ? 159.703 102.480 122.394 1.00 123.17 ? 401 GLY A C   1 
ATOM   3105 O O   . GLY A 1 401 ? 159.360 101.383 121.948 1.00 123.32 ? 401 GLY A O   1 
ATOM   3106 N N   . MET A 1 402 ? 159.200 103.624 121.935 1.00 130.17 ? 402 MET A N   1 
ATOM   3107 C CA  . MET A 1 402 ? 158.298 103.657 120.792 1.00 129.66 ? 402 MET A CA  1 
ATOM   3108 C C   . MET A 1 402 ? 159.000 104.162 119.535 1.00 132.17 ? 402 MET A C   1 
ATOM   3109 O O   . MET A 1 402 ? 158.739 103.660 118.437 1.00 134.20 ? 402 MET A O   1 
ATOM   3110 C CB  . MET A 1 402 ? 157.085 104.538 121.106 1.00 129.50 ? 402 MET A CB  1 
ATOM   3111 C CG  . MET A 1 402 ? 155.955 104.464 120.085 1.00 134.14 ? 402 MET A CG  1 
ATOM   3112 S SD  . MET A 1 402 ? 155.866 102.886 119.214 1.00 143.31 ? 402 MET A SD  1 
ATOM   3113 C CE  . MET A 1 402 ? 154.443 103.155 118.161 1.00 133.36 ? 402 MET A CE  1 
ATOM   3114 N N   . ILE A 1 403 ? 159.893 105.143 119.678 1.00 133.26 ? 403 ILE A N   1 
ATOM   3115 C CA  . ILE A 1 403 ? 160.613 105.670 118.520 1.00 135.21 ? 403 ILE A CA  1 
ATOM   3116 C C   . ILE A 1 403 ? 161.485 104.585 117.900 1.00 135.17 ? 403 ILE A C   1 
ATOM   3117 O O   . ILE A 1 403 ? 161.505 104.400 116.678 1.00 134.62 ? 403 ILE A O   1 
ATOM   3118 C CB  . ILE A 1 403 ? 161.440 106.907 118.919 1.00 133.68 ? 403 ILE A CB  1 
ATOM   3119 C CG1 . ILE A 1 403 ? 160.570 108.165 118.866 1.00 131.37 ? 403 ILE A CG1 1 
ATOM   3120 C CG2 . ILE A 1 403 ? 162.662 107.057 118.021 1.00 132.86 ? 403 ILE A CG2 1 
ATOM   3121 C CD1 . ILE A 1 403 ? 161.318 109.440 119.176 1.00 131.29 ? 403 ILE A CD1 1 
ATOM   3122 N N   . TRP A 1 404 ? 162.216 103.847 118.738 1.00 143.77 ? 404 TRP A N   1 
ATOM   3123 C CA  . TRP A 1 404 ? 162.999 102.723 118.236 1.00 143.62 ? 404 TRP A CA  1 
ATOM   3124 C C   . TRP A 1 404 ? 162.095 101.609 117.724 1.00 143.97 ? 404 TRP A C   1 
ATOM   3125 O O   . TRP A 1 404 ? 162.403 100.964 116.715 1.00 144.21 ? 404 TRP A O   1 
ATOM   3126 C CB  . TRP A 1 404 ? 163.944 102.216 119.328 1.00 142.21 ? 404 TRP A CB  1 
ATOM   3127 C CG  . TRP A 1 404 ? 164.448 100.818 119.121 1.00 144.56 ? 404 TRP A CG  1 
ATOM   3128 C CD1 . TRP A 1 404 ? 165.644 100.453 118.578 1.00 143.68 ? 404 TRP A CD1 1 
ATOM   3129 C CD2 . TRP A 1 404 ? 163.797 99.600  119.510 1.00 146.11 ? 404 TRP A CD2 1 
ATOM   3130 N NE1 . TRP A 1 404 ? 165.764 99.084  118.572 1.00 144.78 ? 404 TRP A NE1 1 
ATOM   3131 C CE2 . TRP A 1 404 ? 164.645 98.538  119.142 1.00 146.54 ? 404 TRP A CE2 1 
ATOM   3132 C CE3 . TRP A 1 404 ? 162.573 99.306  120.121 1.00 142.88 ? 404 TRP A CE3 1 
ATOM   3133 C CZ2 . TRP A 1 404 ? 164.309 97.204  119.364 1.00 145.59 ? 404 TRP A CZ2 1 
ATOM   3134 C CZ3 . TRP A 1 404 ? 162.241 97.982  120.337 1.00 141.72 ? 404 TRP A CZ3 1 
ATOM   3135 C CH2 . TRP A 1 404 ? 163.105 96.948  119.962 1.00 143.67 ? 404 TRP A CH2 1 
ATOM   3136 N N   . TYR A 1 405 ? 160.973 101.368 118.406 1.00 147.28 ? 405 TYR A N   1 
ATOM   3137 C CA  . TYR A 1 405 ? 160.040 100.345 117.945 1.00 148.48 ? 405 TYR A CA  1 
ATOM   3138 C C   . TYR A 1 405 ? 159.341 100.767 116.660 1.00 148.19 ? 405 TYR A C   1 
ATOM   3139 O O   . TYR A 1 405 ? 158.944 99.909  115.863 1.00 147.36 ? 405 TYR A O   1 
ATOM   3140 C CB  . TYR A 1 405 ? 159.014 100.033 119.033 1.00 149.80 ? 405 TYR A CB  1 
ATOM   3141 C CG  . TYR A 1 405 ? 157.941 99.061  118.600 1.00 152.54 ? 405 TYR A CG  1 
ATOM   3142 C CD1 . TYR A 1 405 ? 158.261 97.755  118.249 1.00 152.36 ? 405 TYR A CD1 1 
ATOM   3143 C CD2 . TYR A 1 405 ? 156.609 99.447  118.539 1.00 150.84 ? 405 TYR A CD2 1 
ATOM   3144 C CE1 . TYR A 1 405 ? 157.284 96.861  117.851 1.00 150.88 ? 405 TYR A CE1 1 
ATOM   3145 C CE2 . TYR A 1 405 ? 155.625 98.560  118.142 1.00 149.90 ? 405 TYR A CE2 1 
ATOM   3146 C CZ  . TYR A 1 405 ? 155.969 97.269  117.799 1.00 150.79 ? 405 TYR A CZ  1 
ATOM   3147 O OH  . TYR A 1 405 ? 154.993 96.383  117.404 1.00 150.53 ? 405 TYR A OH  1 
ATOM   3148 N N   . ALA A 1 406 ? 159.176 102.074 116.443 1.00 150.66 ? 406 ALA A N   1 
ATOM   3149 C CA  . ALA A 1 406 ? 158.596 102.547 115.190 1.00 152.76 ? 406 ALA A CA  1 
ATOM   3150 C C   . ALA A 1 406 ? 159.481 102.184 114.004 1.00 155.20 ? 406 ALA A C   1 
ATOM   3151 O O   . ALA A 1 406 ? 158.979 101.816 112.935 1.00 153.02 ? 406 ALA A O   1 
ATOM   3152 C CB  . ALA A 1 406 ? 158.368 104.057 115.250 1.00 150.76 ? 406 ALA A CB  1 
ATOM   3153 N N   . GLU A 1 407 ? 160.802 102.293 114.169 1.00 159.14 ? 407 GLU A N   1 
ATOM   3154 C CA  . GLU A 1 407 ? 161.715 101.876 113.110 1.00 156.55 ? 407 GLU A CA  1 
ATOM   3155 C C   . GLU A 1 407 ? 161.600 100.381 112.842 1.00 156.78 ? 407 GLU A C   1 
ATOM   3156 O O   . GLU A 1 407 ? 161.582 99.950  111.683 1.00 156.80 ? 407 GLU A O   1 
ATOM   3157 C CB  . GLU A 1 407 ? 163.154 102.240 113.478 1.00 155.97 ? 407 GLU A CB  1 
ATOM   3158 C CG  . GLU A 1 407 ? 163.443 103.730 113.509 1.00 157.35 ? 407 GLU A CG  1 
ATOM   3159 C CD  . GLU A 1 407 ? 164.685 104.061 114.312 1.00 157.67 ? 407 GLU A CD  1 
ATOM   3160 O OE1 . GLU A 1 407 ? 165.315 103.123 114.846 1.00 157.62 ? 407 GLU A OE1 1 
ATOM   3161 O OE2 . GLU A 1 407 ? 165.035 105.256 114.407 1.00 158.29 ? 407 GLU A OE2 1 
ATOM   3162 N N   . HIS A 1 408 ? 161.519 99.577  113.897 1.00 153.93 ? 408 HIS A N   1 
ATOM   3163 C CA  . HIS A 1 408 ? 161.418 98.130  113.750 1.00 154.50 ? 408 HIS A CA  1 
ATOM   3164 C C   . HIS A 1 408 ? 159.965 97.695  113.582 1.00 153.46 ? 408 HIS A C   1 
ATOM   3165 O O   . HIS A 1 408 ? 159.285 98.114  112.646 1.00 153.32 ? 408 HIS A O   1 
ATOM   3166 C CB  . HIS A 1 408 ? 162.042 97.421  114.955 1.00 153.14 ? 408 HIS A CB  1 
ATOM   3167 C CG  . HIS A 1 408 ? 163.516 97.645  115.094 1.00 151.79 ? 408 HIS A CG  1 
ATOM   3168 N ND1 . HIS A 1 408 ? 164.061 98.888  115.331 1.00 151.96 ? 408 HIS A ND1 1 
ATOM   3169 C CD2 . HIS A 1 408 ? 164.559 96.784  115.025 1.00 151.02 ? 408 HIS A CD2 1 
ATOM   3170 C CE1 . HIS A 1 408 ? 165.376 98.783  115.406 1.00 151.80 ? 408 HIS A CE1 1 
ATOM   3171 N NE2 . HIS A 1 408 ? 165.704 97.517  115.224 1.00 151.54 ? 408 HIS A NE2 1 
ATOM   3172 N N   . ASP B 1 14  ? 114.494 122.625 115.086 1.00 117.86 ? 14  ASP B N   1 
ATOM   3173 C CA  . ASP B 1 14  ? 115.555 121.691 115.441 1.00 118.63 ? 14  ASP B CA  1 
ATOM   3174 C C   . ASP B 1 14  ? 116.915 122.361 115.305 1.00 117.83 ? 14  ASP B C   1 
ATOM   3175 O O   . ASP B 1 14  ? 117.510 122.785 116.293 1.00 111.37 ? 14  ASP B O   1 
ATOM   3176 C CB  . ASP B 1 14  ? 115.485 120.445 114.561 1.00 120.73 ? 14  ASP B CB  1 
ATOM   3177 C CG  . ASP B 1 14  ? 114.062 120.032 114.256 1.00 118.44 ? 14  ASP B CG  1 
ATOM   3178 O OD1 . ASP B 1 14  ? 113.261 119.913 115.207 1.00 119.01 ? 14  ASP B OD1 1 
ATOM   3179 O OD2 . ASP B 1 14  ? 113.743 119.831 113.067 1.00 114.96 ? 14  ASP B OD2 1 
ATOM   3180 N N   . VAL B 1 15  ? 117.407 122.444 114.067 1.00 122.71 ? 15  VAL B N   1 
ATOM   3181 C CA  . VAL B 1 15  ? 118.643 123.176 113.810 1.00 119.83 ? 15  VAL B CA  1 
ATOM   3182 C C   . VAL B 1 15  ? 118.453 124.652 114.124 1.00 118.59 ? 15  VAL B C   1 
ATOM   3183 O O   . VAL B 1 15  ? 119.314 125.288 114.745 1.00 118.33 ? 15  VAL B O   1 
ATOM   3184 C CB  . VAL B 1 15  ? 119.103 122.954 112.357 1.00 117.27 ? 15  VAL B CB  1 
ATOM   3185 C CG1 . VAL B 1 15  ? 120.142 123.992 111.962 1.00 117.32 ? 15  VAL B CG1 1 
ATOM   3186 C CG2 . VAL B 1 15  ? 119.660 121.548 112.189 1.00 115.07 ? 15  VAL B CG2 1 
ATOM   3187 N N   . ASN B 1 16  ? 117.322 125.222 113.701 1.00 115.01 ? 16  ASN B N   1 
ATOM   3188 C CA  . ASN B 1 16  ? 117.008 126.598 114.070 1.00 112.09 ? 16  ASN B CA  1 
ATOM   3189 C C   . ASN B 1 16  ? 116.648 126.704 115.545 1.00 114.10 ? 16  ASN B C   1 
ATOM   3190 O O   . ASN B 1 16  ? 116.974 127.704 116.195 1.00 114.45 ? 16  ASN B O   1 
ATOM   3191 C CB  . ASN B 1 16  ? 115.869 127.134 113.205 1.00 112.63 ? 16  ASN B CB  1 
ATOM   3192 C CG  . ASN B 1 16  ? 116.248 127.240 111.744 1.00 118.36 ? 16  ASN B CG  1 
ATOM   3193 O OD1 . ASN B 1 16  ? 117.369 126.911 111.357 1.00 118.39 ? 16  ASN B OD1 1 
ATOM   3194 N ND2 . ASN B 1 16  ? 115.312 127.699 110.922 1.00 118.14 ? 16  ASN B ND2 1 
ATOM   3195 N N   . TYR B 1 17  ? 115.978 125.685 116.092 1.00 108.64 ? 17  TYR B N   1 
ATOM   3196 C CA  . TYR B 1 17  ? 115.533 125.752 117.481 1.00 106.24 ? 17  TYR B CA  1 
ATOM   3197 C C   . TYR B 1 17  ? 116.712 125.927 118.428 1.00 104.15 ? 17  TYR B C   1 
ATOM   3198 O O   . TYR B 1 17  ? 116.720 126.836 119.264 1.00 105.20 ? 17  TYR B O   1 
ATOM   3199 C CB  . TYR B 1 17  ? 114.736 124.498 117.847 1.00 103.67 ? 17  TYR B CB  1 
ATOM   3200 C CG  . TYR B 1 17  ? 115.011 124.011 119.252 1.00 106.59 ? 17  TYR B CG  1 
ATOM   3201 C CD1 . TYR B 1 17  ? 114.542 124.708 120.359 1.00 107.47 ? 17  TYR B CD1 1 
ATOM   3202 C CD2 . TYR B 1 17  ? 115.763 122.865 119.472 1.00 107.76 ? 17  TYR B CD2 1 
ATOM   3203 C CE1 . TYR B 1 17  ? 114.808 124.272 121.641 1.00 106.44 ? 17  TYR B CE1 1 
ATOM   3204 C CE2 . TYR B 1 17  ? 116.032 122.422 120.750 1.00 107.88 ? 17  TYR B CE2 1 
ATOM   3205 C CZ  . TYR B 1 17  ? 115.553 123.129 121.830 1.00 105.86 ? 17  TYR B CZ  1 
ATOM   3206 O OH  . TYR B 1 17  ? 115.823 122.688 123.101 1.00 105.89 ? 17  TYR B OH  1 
ATOM   3207 N N   . LYS B 1 18  ? 117.720 125.061 118.315 1.00 98.92  ? 18  LYS B N   1 
ATOM   3208 C CA  . LYS B 1 18  ? 118.888 125.192 119.176 1.00 98.58  ? 18  LYS B CA  1 
ATOM   3209 C C   . LYS B 1 18  ? 119.635 126.484 118.892 1.00 97.02  ? 18  LYS B C   1 
ATOM   3210 O O   . LYS B 1 18  ? 120.161 127.114 119.815 1.00 96.70  ? 18  LYS B O   1 
ATOM   3211 C CB  . LYS B 1 18  ? 119.813 123.989 119.000 1.00 100.17 ? 18  LYS B CB  1 
ATOM   3212 C CG  . LYS B 1 18  ? 120.843 123.834 120.107 1.00 102.56 ? 18  LYS B CG  1 
ATOM   3213 C CD  . LYS B 1 18  ? 120.230 123.211 121.350 1.00 102.77 ? 18  LYS B CD  1 
ATOM   3214 C CE  . LYS B 1 18  ? 120.040 121.714 121.183 1.00 99.89  ? 18  LYS B CE  1 
ATOM   3215 N NZ  . LYS B 1 18  ? 121.320 120.975 121.337 1.00 98.35  ? 18  LYS B NZ  1 
ATOM   3216 N N   . MET B 1 19  ? 119.696 126.891 117.623 1.00 102.52 ? 19  MET B N   1 
ATOM   3217 C CA  . MET B 1 19  ? 120.302 128.174 117.290 1.00 100.73 ? 19  MET B CA  1 
ATOM   3218 C C   . MET B 1 19  ? 119.487 129.328 117.851 1.00 98.05  ? 19  MET B C   1 
ATOM   3219 O O   . MET B 1 19  ? 120.051 130.314 118.335 1.00 104.24 ? 19  MET B O   1 
ATOM   3220 C CB  . MET B 1 19  ? 120.447 128.314 115.775 1.00 101.92 ? 19  MET B CB  1 
ATOM   3221 C CG  . MET B 1 19  ? 120.895 129.696 115.329 1.00 102.85 ? 19  MET B CG  1 
ATOM   3222 S SD  . MET B 1 19  ? 120.275 130.154 113.701 1.00 114.44 ? 19  MET B SD  1 
ATOM   3223 C CE  . MET B 1 19  ? 120.354 131.940 113.803 1.00 97.19  ? 19  MET B CE  1 
ATOM   3224 N N   . HIS B 1 20  ? 118.158 129.231 117.787 1.00 81.72  ? 20  HIS B N   1 
ATOM   3225 C CA  . HIS B 1 20  ? 117.330 130.335 118.254 1.00 84.52  ? 20  HIS B CA  1 
ATOM   3226 C C   . HIS B 1 20  ? 117.363 130.454 119.769 1.00 87.85  ? 20  HIS B C   1 
ATOM   3227 O O   . HIS B 1 20  ? 117.356 131.565 120.310 1.00 82.74  ? 20  HIS B O   1 
ATOM   3228 C CB  . HIS B 1 20  ? 115.895 130.173 117.769 1.00 88.61  ? 20  HIS B CB  1 
ATOM   3229 C CG  . HIS B 1 20  ? 115.325 131.427 117.196 1.00 89.59  ? 20  HIS B CG  1 
ATOM   3230 N ND1 . HIS B 1 20  ? 114.999 132.514 117.977 1.00 89.99  ? 20  HIS B ND1 1 
ATOM   3231 C CD2 . HIS B 1 20  ? 115.030 131.775 115.923 1.00 87.03  ? 20  HIS B CD2 1 
ATOM   3232 C CE1 . HIS B 1 20  ? 114.535 133.481 117.208 1.00 89.77  ? 20  HIS B CE1 1 
ATOM   3233 N NE2 . HIS B 1 20  ? 114.535 133.055 115.958 1.00 88.98  ? 20  HIS B NE2 1 
ATOM   3234 N N   . PHE B 1 21  ? 117.383 129.323 120.473 1.00 79.04  ? 21  PHE B N   1 
ATOM   3235 C CA  . PHE B 1 21  ? 117.514 129.376 121.922 1.00 68.33  ? 21  PHE B CA  1 
ATOM   3236 C C   . PHE B 1 21  ? 118.879 129.900 122.337 1.00 71.75  ? 21  PHE B C   1 
ATOM   3237 O O   . PHE B 1 21  ? 118.998 130.564 123.370 1.00 84.04  ? 21  PHE B O   1 
ATOM   3238 C CB  . PHE B 1 21  ? 117.273 127.999 122.526 1.00 68.59  ? 21  PHE B CB  1 
ATOM   3239 C CG  . PHE B 1 21  ? 117.677 127.900 123.958 1.00 70.29  ? 21  PHE B CG  1 
ATOM   3240 C CD1 . PHE B 1 21  ? 117.001 128.611 124.928 1.00 72.25  ? 21  PHE B CD1 1 
ATOM   3241 C CD2 . PHE B 1 21  ? 118.739 127.105 124.336 1.00 73.58  ? 21  PHE B CD2 1 
ATOM   3242 C CE1 . PHE B 1 21  ? 117.371 128.523 126.244 1.00 66.25  ? 21  PHE B CE1 1 
ATOM   3243 C CE2 . PHE B 1 21  ? 119.112 127.016 125.651 1.00 74.36  ? 21  PHE B CE2 1 
ATOM   3244 C CZ  . PHE B 1 21  ? 118.424 127.724 126.605 1.00 71.44  ? 21  PHE B CZ  1 
ATOM   3245 N N   . ARG B 1 22  ? 119.917 129.617 121.550 1.00 75.05  ? 22  ARG B N   1 
ATOM   3246 C CA  . ARG B 1 22  ? 121.230 130.175 121.836 1.00 71.37  ? 22  ARG B CA  1 
ATOM   3247 C C   . ARG B 1 22  ? 121.234 131.693 121.742 1.00 72.93  ? 22  ARG B C   1 
ATOM   3248 O O   . ARG B 1 22  ? 122.069 132.338 122.381 1.00 81.47  ? 22  ARG B O   1 
ATOM   3249 C CB  . ARG B 1 22  ? 122.266 129.589 120.881 1.00 74.61  ? 22  ARG B CB  1 
ATOM   3250 C CG  . ARG B 1 22  ? 123.701 129.772 121.325 1.00 74.80  ? 22  ARG B CG  1 
ATOM   3251 C CD  . ARG B 1 22  ? 124.441 128.451 121.289 1.00 78.92  ? 22  ARG B CD  1 
ATOM   3252 N NE  . ARG B 1 22  ? 124.482 127.894 119.944 1.00 89.18  ? 22  ARG B NE  1 
ATOM   3253 C CZ  . ARG B 1 22  ? 124.451 126.597 119.670 1.00 88.27  ? 22  ARG B CZ  1 
ATOM   3254 N NH1 . ARG B 1 22  ? 124.378 125.690 120.630 1.00 86.07  ? 22  ARG B NH1 1 
ATOM   3255 N NH2 . ARG B 1 22  ? 124.489 126.200 118.401 1.00 83.08  ? 22  ARG B NH2 1 
ATOM   3256 N N   . MET B 1 23  ? 120.320 132.278 120.970 1.00 74.80  ? 23  MET B N   1 
ATOM   3257 C CA  . MET B 1 23  ? 120.238 133.730 120.890 1.00 73.95  ? 23  MET B CA  1 
ATOM   3258 C C   . MET B 1 23  ? 119.617 134.341 122.136 1.00 76.91  ? 23  MET B C   1 
ATOM   3259 O O   . MET B 1 23  ? 119.791 135.540 122.373 1.00 76.93  ? 23  MET B O   1 
ATOM   3260 C CB  . MET B 1 23  ? 119.440 134.145 119.656 1.00 80.78  ? 23  MET B CB  1 
ATOM   3261 C CG  . MET B 1 23  ? 120.196 133.985 118.351 1.00 83.62  ? 23  MET B CG  1 
ATOM   3262 S SD  . MET B 1 23  ? 119.111 133.984 116.912 1.00 98.24  ? 23  MET B SD  1 
ATOM   3263 C CE  . MET B 1 23  ? 117.771 135.020 117.493 1.00 82.47  ? 23  MET B CE  1 
ATOM   3264 N N   . ILE B 1 24  ? 118.896 133.556 122.929 1.00 70.60  ? 24  ILE B N   1 
ATOM   3265 C CA  . ILE B 1 24  ? 118.348 134.024 124.192 1.00 64.54  ? 24  ILE B CA  1 
ATOM   3266 C C   . ILE B 1 24  ? 119.272 133.698 125.356 1.00 66.17  ? 24  ILE B C   1 
ATOM   3267 O O   . ILE B 1 24  ? 119.477 134.530 126.240 1.00 72.52  ? 24  ILE B O   1 
ATOM   3268 C CB  . ILE B 1 24  ? 116.944 133.433 124.430 1.00 66.02  ? 24  ILE B CB  1 
ATOM   3269 C CG1 . ILE B 1 24  ? 116.135 133.400 123.140 1.00 70.10  ? 24  ILE B CG1 1 
ATOM   3270 C CG2 . ILE B 1 24  ? 116.200 134.260 125.437 1.00 69.56  ? 24  ILE B CG2 1 
ATOM   3271 C CD1 . ILE B 1 24  ? 114.714 132.930 123.353 1.00 68.74  ? 24  ILE B CD1 1 
ATOM   3272 N N   . ASN B 1 25  ? 119.837 132.492 125.376 1.00 48.88  ? 25  ASN B N   1 
ATOM   3273 C CA  . ASN B 1 25  ? 120.708 132.106 126.479 1.00 49.98  ? 25  ASN B CA  1 
ATOM   3274 C C   . ASN B 1 25  ? 122.093 132.725 126.345 1.00 60.33  ? 25  ASN B C   1 
ATOM   3275 O O   . ASN B 1 25  ? 122.516 133.509 127.198 1.00 67.25  ? 25  ASN B O   1 
ATOM   3276 C CB  . ASN B 1 25  ? 120.817 130.585 126.557 1.00 57.83  ? 25  ASN B CB  1 
ATOM   3277 C CG  . ASN B 1 25  ? 120.385 130.046 127.890 1.00 65.64  ? 25  ASN B CG  1 
ATOM   3278 O OD1 . ASN B 1 25  ? 119.639 130.695 128.618 1.00 70.57  ? 25  ASN B OD1 1 
ATOM   3279 N ND2 . ASN B 1 25  ? 120.867 128.860 128.233 1.00 62.28  ? 25  ASN B ND2 1 
ATOM   3280 N N   . GLU B 1 26  ? 122.817 132.385 125.283 1.00 67.76  ? 26  GLU B N   1 
ATOM   3281 C CA  . GLU B 1 26  ? 124.212 132.790 125.122 1.00 64.21  ? 26  GLU B CA  1 
ATOM   3282 C C   . GLU B 1 26  ? 124.327 133.673 123.888 1.00 65.55  ? 26  GLU B C   1 
ATOM   3283 O O   . GLU B 1 26  ? 124.661 133.202 122.802 1.00 79.38  ? 26  GLU B O   1 
ATOM   3284 C CB  . GLU B 1 26  ? 125.113 131.567 125.016 1.00 66.95  ? 26  GLU B CB  1 
ATOM   3285 C CG  . GLU B 1 26  ? 125.433 130.907 126.342 1.00 75.90  ? 26  GLU B CG  1 
ATOM   3286 C CD  . GLU B 1 26  ? 125.403 129.393 126.260 1.00 84.94  ? 26  GLU B CD  1 
ATOM   3287 O OE1 . GLU B 1 26  ? 124.493 128.849 125.600 1.00 83.55  ? 26  GLU B OE1 1 
ATOM   3288 O OE2 . GLU B 1 26  ? 126.290 128.747 126.853 1.00 80.90  ? 26  GLU B OE2 1 
ATOM   3289 N N   . GLN B 1 27  ? 124.069 134.963 124.061 1.00 59.95  ? 27  GLN B N   1 
ATOM   3290 C CA  . GLN B 1 27  ? 124.234 135.899 122.959 1.00 61.51  ? 27  GLN B CA  1 
ATOM   3291 C C   . GLN B 1 27  ? 125.714 136.138 122.703 1.00 68.92  ? 27  GLN B C   1 
ATOM   3292 O O   . GLN B 1 27  ? 126.484 136.383 123.636 1.00 74.58  ? 27  GLN B O   1 
ATOM   3293 C CB  . GLN B 1 27  ? 123.528 137.214 123.268 1.00 65.92  ? 27  GLN B CB  1 
ATOM   3294 C CG  . GLN B 1 27  ? 123.437 138.151 122.083 1.00 69.52  ? 27  GLN B CG  1 
ATOM   3295 C CD  . GLN B 1 27  ? 122.262 137.837 121.190 1.00 75.98  ? 27  GLN B CD  1 
ATOM   3296 O OE1 . GLN B 1 27  ? 121.127 138.205 121.486 1.00 74.35  ? 27  GLN B OE1 1 
ATOM   3297 N NE2 . GLN B 1 27  ? 122.526 137.150 120.088 1.00 78.30  ? 27  GLN B NE2 1 
ATOM   3298 N N   . GLN B 1 28  ? 126.113 136.066 121.438 1.00 72.92  ? 28  GLN B N   1 
ATOM   3299 C CA  . GLN B 1 28  ? 127.508 136.226 121.063 1.00 77.08  ? 28  GLN B CA  1 
ATOM   3300 C C   . GLN B 1 28  ? 127.821 137.686 120.765 1.00 79.33  ? 28  GLN B C   1 
ATOM   3301 O O   . GLN B 1 28  ? 126.941 138.471 120.405 1.00 82.44  ? 28  GLN B O   1 
ATOM   3302 C CB  . GLN B 1 28  ? 127.842 135.366 119.846 1.00 72.87  ? 28  GLN B CB  1 
ATOM   3303 C CG  . GLN B 1 28  ? 128.545 134.064 120.181 1.00 78.59  ? 28  GLN B CG  1 
ATOM   3304 C CD  . GLN B 1 28  ? 127.576 132.957 120.534 1.00 81.35  ? 28  GLN B CD  1 
ATOM   3305 O OE1 . GLN B 1 28  ? 126.497 132.853 119.953 1.00 77.53  ? 28  GLN B OE1 1 
ATOM   3306 N NE2 . GLN B 1 28  ? 127.956 132.120 121.492 1.00 80.23  ? 28  GLN B NE2 1 
ATOM   3307 N N   . VAL B 1 29  ? 129.092 138.040 120.915 1.00 77.99  ? 29  VAL B N   1 
ATOM   3308 C CA  . VAL B 1 29  ? 129.550 139.398 120.644 1.00 73.89  ? 29  VAL B CA  1 
ATOM   3309 C C   . VAL B 1 29  ? 129.797 139.551 119.152 1.00 75.00  ? 29  VAL B C   1 
ATOM   3310 O O   . VAL B 1 29  ? 130.440 138.701 118.525 1.00 80.40  ? 29  VAL B O   1 
ATOM   3311 C CB  . VAL B 1 29  ? 130.820 139.712 121.445 1.00 75.03  ? 29  VAL B CB  1 
ATOM   3312 C CG1 . VAL B 1 29  ? 131.083 141.201 121.438 1.00 74.77  ? 29  VAL B CG1 1 
ATOM   3313 C CG2 . VAL B 1 29  ? 130.694 139.190 122.858 1.00 72.91  ? 29  VAL B CG2 1 
ATOM   3314 N N   . GLU B 1 30  ? 129.295 140.637 118.579 1.00 80.26  ? 30  GLU B N   1 
ATOM   3315 C CA  . GLU B 1 30  ? 129.426 140.898 117.155 1.00 85.22  ? 30  GLU B CA  1 
ATOM   3316 C C   . GLU B 1 30  ? 130.504 141.944 116.906 1.00 89.61  ? 30  GLU B C   1 
ATOM   3317 O O   . GLU B 1 30  ? 130.651 142.894 117.680 1.00 91.41  ? 30  GLU B O   1 
ATOM   3318 C CB  . GLU B 1 30  ? 128.097 141.371 116.566 1.00 87.03  ? 30  GLU B CB  1 
ATOM   3319 C CG  . GLU B 1 30  ? 127.219 140.248 116.050 1.00 87.33  ? 30  GLU B CG  1 
ATOM   3320 C CD  . GLU B 1 30  ? 125.811 140.709 115.744 1.00 91.53  ? 30  GLU B CD  1 
ATOM   3321 O OE1 . GLU B 1 30  ? 125.202 141.370 116.610 1.00 93.82  ? 30  GLU B OE1 1 
ATOM   3322 O OE2 . GLU B 1 30  ? 125.312 140.410 114.639 1.00 88.94  ? 30  GLU B OE2 1 
ATOM   3323 N N   . ASP B 1 31  ? 131.254 141.759 115.819 1.00 86.60  ? 31  ASP B N   1 
ATOM   3324 C CA  . ASP B 1 31  ? 132.277 142.707 115.380 1.00 84.13  ? 31  ASP B CA  1 
ATOM   3325 C C   . ASP B 1 31  ? 133.328 142.905 116.475 1.00 84.25  ? 31  ASP B C   1 
ATOM   3326 O O   . ASP B 1 31  ? 133.482 143.985 117.047 1.00 81.70  ? 31  ASP B O   1 
ATOM   3327 C CB  . ASP B 1 31  ? 131.634 144.036 114.961 1.00 87.62  ? 31  ASP B CB  1 
ATOM   3328 C CG  . ASP B 1 31  ? 132.625 145.019 114.349 1.00 90.62  ? 31  ASP B CG  1 
ATOM   3329 O OD1 . ASP B 1 31  ? 132.164 145.990 113.715 1.00 91.44  ? 31  ASP B OD1 1 
ATOM   3330 O OD2 . ASP B 1 31  ? 133.852 144.823 114.469 1.00 89.99  ? 31  ASP B OD2 1 
ATOM   3331 N N   . ILE B 1 32  ? 134.046 141.825 116.769 1.00 83.68  ? 32  ILE B N   1 
ATOM   3332 C CA  . ILE B 1 32  ? 135.102 141.852 117.775 1.00 81.45  ? 32  ILE B CA  1 
ATOM   3333 C C   . ILE B 1 32  ? 136.350 142.456 117.140 1.00 84.27  ? 32  ILE B C   1 
ATOM   3334 O O   . ILE B 1 32  ? 136.956 141.856 116.250 1.00 85.92  ? 32  ILE B O   1 
ATOM   3335 C CB  . ILE B 1 32  ? 135.389 140.453 118.327 1.00 78.12  ? 32  ILE B CB  1 
ATOM   3336 C CG1 . ILE B 1 32  ? 134.195 139.936 119.126 1.00 79.34  ? 32  ILE B CG1 1 
ATOM   3337 C CG2 . ILE B 1 32  ? 136.630 140.476 119.188 1.00 83.98  ? 32  ILE B CG2 1 
ATOM   3338 C CD1 . ILE B 1 32  ? 134.177 138.434 119.280 1.00 82.63  ? 32  ILE B CD1 1 
ATOM   3339 N N   . THR B 1 33  ? 136.741 143.643 117.602 1.00 89.91  ? 33  THR B N   1 
ATOM   3340 C CA  . THR B 1 33  ? 137.935 144.317 117.105 1.00 91.49  ? 33  THR B CA  1 
ATOM   3341 C C   . THR B 1 33  ? 139.128 144.103 118.030 1.00 91.36  ? 33  THR B C   1 
ATOM   3342 O O   . THR B 1 33  ? 140.180 143.627 117.593 1.00 94.21  ? 33  THR B O   1 
ATOM   3343 C CB  . THR B 1 33  ? 137.667 145.815 116.928 1.00 91.43  ? 33  THR B CB  1 
ATOM   3344 O OG1 . THR B 1 33  ? 137.136 146.353 118.145 1.00 93.94  ? 33  THR B OG1 1 
ATOM   3345 C CG2 . THR B 1 33  ? 136.680 146.047 115.800 1.00 87.43  ? 33  THR B CG2 1 
ATOM   3346 N N   . ILE B 1 34  ? 138.984 144.450 119.306 1.00 80.73  ? 34  ILE B N   1 
ATOM   3347 C CA  . ILE B 1 34  ? 140.022 144.162 120.286 1.00 80.04  ? 34  ILE B CA  1 
ATOM   3348 C C   . ILE B 1 34  ? 139.827 142.733 120.767 1.00 84.21  ? 34  ILE B C   1 
ATOM   3349 O O   . ILE B 1 34  ? 139.122 142.488 121.751 1.00 86.13  ? 34  ILE B O   1 
ATOM   3350 C CB  . ILE B 1 34  ? 139.989 145.157 121.457 1.00 77.15  ? 34  ILE B CB  1 
ATOM   3351 C CG1 . ILE B 1 34  ? 140.034 146.591 120.935 1.00 82.30  ? 34  ILE B CG1 1 
ATOM   3352 C CG2 . ILE B 1 34  ? 141.148 144.908 122.398 1.00 82.51  ? 34  ILE B CG2 1 
ATOM   3353 C CD1 . ILE B 1 34  ? 140.290 147.620 122.008 1.00 84.59  ? 34  ILE B CD1 1 
ATOM   3354 N N   . ASP B 1 35  ? 140.451 141.781 120.071 1.00 82.97  ? 35  ASP B N   1 
ATOM   3355 C CA  . ASP B 1 35  ? 140.272 140.370 120.392 1.00 83.53  ? 35  ASP B CA  1 
ATOM   3356 C C   . ASP B 1 35  ? 140.825 140.013 121.763 1.00 84.22  ? 35  ASP B C   1 
ATOM   3357 O O   . ASP B 1 35  ? 140.476 138.959 122.302 1.00 84.13  ? 35  ASP B O   1 
ATOM   3358 C CB  . ASP B 1 35  ? 140.935 139.505 119.319 1.00 88.61  ? 35  ASP B CB  1 
ATOM   3359 C CG  . ASP B 1 35  ? 140.599 138.034 119.461 1.00 92.67  ? 35  ASP B CG  1 
ATOM   3360 O OD1 . ASP B 1 35  ? 141.424 137.191 119.050 1.00 94.03  ? 35  ASP B OD1 1 
ATOM   3361 O OD2 . ASP B 1 35  ? 139.506 137.718 119.977 1.00 88.54  ? 35  ASP B OD2 1 
ATOM   3362 N N   . PHE B 1 36  ? 141.674 140.865 122.338 1.00 82.18  ? 36  PHE B N   1 
ATOM   3363 C CA  . PHE B 1 36  ? 142.240 140.574 123.650 1.00 84.53  ? 36  PHE B CA  1 
ATOM   3364 C C   . PHE B 1 36  ? 141.150 140.474 124.709 1.00 85.66  ? 36  PHE B C   1 
ATOM   3365 O O   . PHE B 1 36  ? 141.211 139.612 125.592 1.00 84.85  ? 36  PHE B O   1 
ATOM   3366 C CB  . PHE B 1 36  ? 143.265 141.649 124.017 1.00 84.02  ? 36  PHE B CB  1 
ATOM   3367 C CG  . PHE B 1 36  ? 143.224 142.073 125.457 1.00 84.84  ? 36  PHE B CG  1 
ATOM   3368 C CD1 . PHE B 1 36  ? 143.683 141.235 126.460 1.00 84.60  ? 36  PHE B CD1 1 
ATOM   3369 C CD2 . PHE B 1 36  ? 142.731 143.317 125.806 1.00 82.31  ? 36  PHE B CD2 1 
ATOM   3370 C CE1 . PHE B 1 36  ? 143.644 141.626 127.781 1.00 83.01  ? 36  PHE B CE1 1 
ATOM   3371 C CE2 . PHE B 1 36  ? 142.691 143.715 127.125 1.00 83.14  ? 36  PHE B CE2 1 
ATOM   3372 C CZ  . PHE B 1 36  ? 143.148 142.868 128.114 1.00 82.72  ? 36  PHE B CZ  1 
ATOM   3373 N N   . PHE B 1 37  ? 140.140 141.340 124.632 1.00 77.87  ? 37  PHE B N   1 
ATOM   3374 C CA  . PHE B 1 37  ? 139.090 141.363 125.641 1.00 72.55  ? 37  PHE B CA  1 
ATOM   3375 C C   . PHE B 1 37  ? 138.220 140.116 125.632 1.00 75.23  ? 37  PHE B C   1 
ATOM   3376 O O   . PHE B 1 37  ? 137.463 139.912 126.585 1.00 77.05  ? 37  PHE B O   1 
ATOM   3377 C CB  . PHE B 1 37  ? 138.205 142.592 125.451 1.00 73.46  ? 37  PHE B CB  1 
ATOM   3378 C CG  . PHE B 1 37  ? 138.659 143.788 126.225 1.00 72.98  ? 37  PHE B CG  1 
ATOM   3379 C CD1 . PHE B 1 37  ? 138.485 143.849 127.593 1.00 73.11  ? 37  PHE B CD1 1 
ATOM   3380 C CD2 . PHE B 1 37  ? 139.259 144.854 125.585 1.00 75.52  ? 37  PHE B CD2 1 
ATOM   3381 C CE1 . PHE B 1 37  ? 138.903 144.949 128.305 1.00 76.14  ? 37  PHE B CE1 1 
ATOM   3382 C CE2 . PHE B 1 37  ? 139.675 145.954 126.295 1.00 74.19  ? 37  PHE B CE2 1 
ATOM   3383 C CZ  . PHE B 1 37  ? 139.497 146.001 127.655 1.00 75.44  ? 37  PHE B CZ  1 
ATOM   3384 N N   . TYR B 1 38  ? 138.300 139.282 124.594 1.00 79.20  ? 38  TYR B N   1 
ATOM   3385 C CA  . TYR B 1 38  ? 137.425 138.127 124.475 1.00 75.31  ? 38  TYR B CA  1 
ATOM   3386 C C   . TYR B 1 38  ? 138.152 136.796 124.357 1.00 73.74  ? 38  TYR B C   1 
ATOM   3387 O O   . TYR B 1 38  ? 137.495 135.753 124.425 1.00 70.09  ? 38  TYR B O   1 
ATOM   3388 C CB  . TYR B 1 38  ? 136.493 138.288 123.266 1.00 73.19  ? 38  TYR B CB  1 
ATOM   3389 C CG  . TYR B 1 38  ? 135.590 139.491 123.360 1.00 72.19  ? 38  TYR B CG  1 
ATOM   3390 C CD1 . TYR B 1 38  ? 134.507 139.500 124.221 1.00 75.37  ? 38  TYR B CD1 1 
ATOM   3391 C CD2 . TYR B 1 38  ? 135.822 140.619 122.593 1.00 70.11  ? 38  TYR B CD2 1 
ATOM   3392 C CE1 . TYR B 1 38  ? 133.680 140.594 124.313 1.00 76.72  ? 38  TYR B CE1 1 
ATOM   3393 C CE2 . TYR B 1 38  ? 135.000 141.718 122.680 1.00 72.62  ? 38  TYR B CE2 1 
ATOM   3394 C CZ  . TYR B 1 38  ? 133.931 141.698 123.543 1.00 72.87  ? 38  TYR B CZ  1 
ATOM   3395 O OH  . TYR B 1 38  ? 133.102 142.787 123.639 1.00 71.61  ? 38  TYR B OH  1 
ATOM   3396 N N   . ARG B 1 39  ? 139.462 136.791 124.183 1.00 85.31  ? 39  ARG B N   1 
ATOM   3397 C CA  . ARG B 1 39  ? 140.195 135.533 124.119 1.00 80.28  ? 39  ARG B CA  1 
ATOM   3398 C C   . ARG B 1 39  ? 140.228 134.894 125.498 1.00 79.48  ? 39  ARG B C   1 
ATOM   3399 O O   . ARG B 1 39  ? 140.700 135.528 126.450 1.00 83.80  ? 39  ARG B O   1 
ATOM   3400 C CB  . ARG B 1 39  ? 141.614 135.762 123.613 1.00 79.80  ? 39  ARG B CB  1 
ATOM   3401 C CG  . ARG B 1 39  ? 141.735 135.874 122.106 1.00 80.14  ? 39  ARG B CG  1 
ATOM   3402 C CD  . ARG B 1 39  ? 143.189 135.837 121.680 1.00 79.69  ? 39  ARG B CD  1 
ATOM   3403 N NE  . ARG B 1 39  ? 144.003 135.062 122.608 1.00 85.49  ? 39  ARG B NE  1 
ATOM   3404 C CZ  . ARG B 1 39  ? 145.257 134.696 122.379 1.00 86.25  ? 39  ARG B CZ  1 
ATOM   3405 N NH1 . ARG B 1 39  ? 145.878 135.022 121.258 1.00 84.30  ? 39  ARG B NH1 1 
ATOM   3406 N NH2 . ARG B 1 39  ? 145.904 133.985 123.299 1.00 82.99  ? 39  ARG B NH2 1 
ATOM   3407 N N   . PRO B 1 40  ? 139.747 133.665 125.659 1.00 71.42  ? 40  PRO B N   1 
ATOM   3408 C CA  . PRO B 1 40  ? 139.787 133.031 126.977 1.00 66.34  ? 40  PRO B CA  1 
ATOM   3409 C C   . PRO B 1 40  ? 141.212 132.740 127.409 1.00 72.15  ? 40  PRO B C   1 
ATOM   3410 O O   . PRO B 1 40  ? 142.094 132.468 126.593 1.00 79.00  ? 40  PRO B O   1 
ATOM   3411 C CB  . PRO B 1 40  ? 139.001 131.738 126.766 1.00 62.89  ? 40  PRO B CB  1 
ATOM   3412 C CG  . PRO B 1 40  ? 139.212 131.428 125.346 1.00 68.43  ? 40  PRO B CG  1 
ATOM   3413 C CD  . PRO B 1 40  ? 139.240 132.747 124.630 1.00 70.83  ? 40  PRO B CD  1 
ATOM   3414 N N   . HIS B 1 41  ? 141.429 132.803 128.716 1.00 74.15  ? 41  HIS B N   1 
ATOM   3415 C CA  . HIS B 1 41  ? 142.703 132.467 129.337 1.00 69.15  ? 41  HIS B CA  1 
ATOM   3416 C C   . HIS B 1 41  ? 142.464 131.601 130.562 1.00 72.51  ? 41  HIS B C   1 
ATOM   3417 O O   . HIS B 1 41  ? 142.986 131.846 131.649 1.00 71.61  ? 41  HIS B O   1 
ATOM   3418 C CB  . HIS B 1 41  ? 143.480 133.728 129.679 1.00 69.40  ? 41  HIS B CB  1 
ATOM   3419 C CG  . HIS B 1 41  ? 144.031 134.434 128.481 1.00 75.42  ? 41  HIS B CG  1 
ATOM   3420 N ND1 . HIS B 1 41  ? 143.844 135.780 128.258 1.00 79.17  ? 41  HIS B ND1 1 
ATOM   3421 C CD2 . HIS B 1 41  ? 144.761 133.977 127.437 1.00 73.31  ? 41  HIS B CD2 1 
ATOM   3422 C CE1 . HIS B 1 41  ? 144.439 136.124 127.130 1.00 77.50  ? 41  HIS B CE1 1 
ATOM   3423 N NE2 . HIS B 1 41  ? 145.002 135.048 126.612 1.00 76.83  ? 41  HIS B NE2 1 
ATOM   3424 N N   . THR B 1 42  ? 141.654 130.558 130.382 1.00 60.20  ? 42  THR B N   1 
ATOM   3425 C CA  . THR B 1 42  ? 141.147 129.765 131.492 1.00 52.00  ? 42  THR B CA  1 
ATOM   3426 C C   . THR B 1 42  ? 142.229 128.997 132.239 1.00 58.89  ? 42  THR B C   1 
ATOM   3427 O O   . THR B 1 42  ? 141.951 128.491 133.329 1.00 60.09  ? 42  THR B O   1 
ATOM   3428 C CB  . THR B 1 42  ? 140.083 128.798 130.984 1.00 42.27  ? 42  THR B CB  1 
ATOM   3429 O OG1 . THR B 1 42  ? 139.729 127.887 132.026 1.00 59.12  ? 42  THR B OG1 1 
ATOM   3430 C CG2 . THR B 1 42  ? 140.604 128.023 129.807 1.00 49.27  ? 42  THR B CG2 1 
ATOM   3431 N N   . ILE B 1 43  ? 143.440 128.883 131.695 1.00 67.56  ? 43  ILE B N   1 
ATOM   3432 C CA  . ILE B 1 43  ? 144.527 128.296 132.472 1.00 54.31  ? 43  ILE B CA  1 
ATOM   3433 C C   . ILE B 1 43  ? 145.157 129.344 133.377 1.00 56.09  ? 43  ILE B C   1 
ATOM   3434 O O   . ILE B 1 43  ? 145.525 129.053 134.519 1.00 65.19  ? 43  ILE B O   1 
ATOM   3435 C CB  . ILE B 1 43  ? 145.567 127.640 131.549 1.00 57.54  ? 43  ILE B CB  1 
ATOM   3436 C CG1 . ILE B 1 43  ? 144.983 126.387 130.903 1.00 62.97  ? 43  ILE B CG1 1 
ATOM   3437 C CG2 . ILE B 1 43  ? 146.804 127.267 132.328 1.00 56.49  ? 43  ILE B CG2 1 
ATOM   3438 C CD1 . ILE B 1 43  ? 145.971 125.614 130.073 1.00 59.68  ? 43  ILE B CD1 1 
ATOM   3439 N N   . THR B 1 44  ? 145.288 130.579 132.891 1.00 63.17  ? 44  THR B N   1 
ATOM   3440 C CA  . THR B 1 44  ? 145.704 131.668 133.767 1.00 60.76  ? 44  THR B CA  1 
ATOM   3441 C C   . THR B 1 44  ? 144.701 131.875 134.891 1.00 63.54  ? 44  THR B C   1 
ATOM   3442 O O   . THR B 1 44  ? 145.089 132.183 136.022 1.00 70.07  ? 44  THR B O   1 
ATOM   3443 C CB  . THR B 1 44  ? 145.875 132.959 132.970 1.00 59.30  ? 44  THR B CB  1 
ATOM   3444 O OG1 . THR B 1 44  ? 146.678 132.705 131.813 1.00 66.21  ? 44  THR B OG1 1 
ATOM   3445 C CG2 . THR B 1 44  ? 146.559 134.009 133.813 1.00 63.30  ? 44  THR B CG2 1 
ATOM   3446 N N   . LEU B 1 45  ? 143.411 131.710 134.600 1.00 57.39  ? 45  LEU B N   1 
ATOM   3447 C CA  . LEU B 1 45  ? 142.404 131.746 135.652 1.00 55.63  ? 45  LEU B CA  1 
ATOM   3448 C C   . LEU B 1 45  ? 142.523 130.545 136.578 1.00 54.50  ? 45  LEU B C   1 
ATOM   3449 O O   . LEU B 1 45  ? 142.086 130.609 137.729 1.00 59.67  ? 45  LEU B O   1 
ATOM   3450 C CB  . LEU B 1 45  ? 141.009 131.805 135.040 1.00 53.09  ? 45  LEU B CB  1 
ATOM   3451 C CG  . LEU B 1 45  ? 139.882 132.249 135.959 1.00 51.08  ? 45  LEU B CG  1 
ATOM   3452 C CD1 . LEU B 1 45  ? 140.157 133.643 136.452 1.00 58.18  ? 45  LEU B CD1 1 
ATOM   3453 C CD2 . LEU B 1 45  ? 138.569 132.201 135.219 1.00 55.86  ? 45  LEU B CD2 1 
ATOM   3454 N N   . LEU B 1 46  ? 143.092 129.440 136.095 1.00 54.57  ? 46  LEU B N   1 
ATOM   3455 C CA  . LEU B 1 46  ? 143.335 128.297 136.969 1.00 52.59  ? 46  LEU B CA  1 
ATOM   3456 C C   . LEU B 1 46  ? 144.515 128.555 137.893 1.00 52.57  ? 46  LEU B C   1 
ATOM   3457 O O   . LEU B 1 46  ? 144.470 128.210 139.078 1.00 61.58  ? 46  LEU B O   1 
ATOM   3458 C CB  . LEU B 1 46  ? 143.572 127.040 136.134 1.00 53.42  ? 46  LEU B CB  1 
ATOM   3459 C CG  . LEU B 1 46  ? 144.354 125.898 136.773 1.00 48.18  ? 46  LEU B CG  1 
ATOM   3460 C CD1 . LEU B 1 46  ? 143.503 125.213 137.791 1.00 51.13  ? 46  LEU B CD1 1 
ATOM   3461 C CD2 . LEU B 1 46  ? 144.785 124.911 135.719 1.00 54.23  ? 46  LEU B CD2 1 
ATOM   3462 N N   . SER B 1 47  ? 145.582 129.159 137.371 1.00 49.50  ? 47  SER B N   1 
ATOM   3463 C CA  . SER B 1 47  ? 146.738 129.456 138.204 1.00 48.42  ? 47  SER B CA  1 
ATOM   3464 C C   . SER B 1 47  ? 146.455 130.583 139.183 1.00 58.40  ? 47  SER B C   1 
ATOM   3465 O O   . SER B 1 47  ? 147.049 130.623 140.263 1.00 67.65  ? 47  SER B O   1 
ATOM   3466 C CB  . SER B 1 47  ? 147.938 129.812 137.336 1.00 52.29  ? 47  SER B CB  1 
ATOM   3467 O OG  . SER B 1 47  ? 149.134 129.745 138.088 1.00 61.06  ? 47  SER B OG  1 
ATOM   3468 N N   . PHE B 1 48  ? 145.577 131.517 138.817 1.00 59.26  ? 48  PHE B N   1 
ATOM   3469 C CA  . PHE B 1 48  ? 145.264 132.620 139.717 1.00 51.20  ? 48  PHE B CA  1 
ATOM   3470 C C   . PHE B 1 48  ? 144.562 132.127 140.975 1.00 55.94  ? 48  PHE B C   1 
ATOM   3471 O O   . PHE B 1 48  ? 144.896 132.560 142.081 1.00 62.68  ? 48  PHE B O   1 
ATOM   3472 C CB  . PHE B 1 48  ? 144.410 133.660 138.996 1.00 51.93  ? 48  PHE B CB  1 
ATOM   3473 C CG  . PHE B 1 48  ? 143.529 134.463 139.909 1.00 59.22  ? 48  PHE B CG  1 
ATOM   3474 C CD1 . PHE B 1 48  ? 144.045 135.521 140.635 1.00 61.39  ? 48  PHE B CD1 1 
ATOM   3475 C CD2 . PHE B 1 48  ? 142.180 134.170 140.031 1.00 57.37  ? 48  PHE B CD2 1 
ATOM   3476 C CE1 . PHE B 1 48  ? 143.238 136.263 141.473 1.00 62.99  ? 48  PHE B CE1 1 
ATOM   3477 C CE2 . PHE B 1 48  ? 141.370 134.909 140.867 1.00 58.82  ? 48  PHE B CE2 1 
ATOM   3478 C CZ  . PHE B 1 48  ? 141.900 135.956 141.588 1.00 62.99  ? 48  PHE B CZ  1 
ATOM   3479 N N   . THR B 1 49  ? 143.588 131.224 140.831 1.00 52.31  ? 49  THR B N   1 
ATOM   3480 C CA  . THR B 1 49  ? 142.852 130.752 142.000 1.00 50.00  ? 49  THR B CA  1 
ATOM   3481 C C   . THR B 1 49  ? 143.738 129.932 142.925 1.00 58.03  ? 49  THR B C   1 
ATOM   3482 O O   . THR B 1 49  ? 143.708 130.121 144.145 1.00 66.96  ? 49  THR B O   1 
ATOM   3483 C CB  . THR B 1 49  ? 141.639 129.929 141.580 1.00 46.77  ? 49  THR B CB  1 
ATOM   3484 O OG1 . THR B 1 49  ? 142.074 128.686 141.025 1.00 56.15  ? 49  THR B OG1 1 
ATOM   3485 C CG2 . THR B 1 49  ? 140.823 130.675 140.556 1.00 54.96  ? 49  THR B CG2 1 
ATOM   3486 N N   . ILE B 1 50  ? 144.533 129.020 142.369 1.00 49.14  ? 50  ILE B N   1 
ATOM   3487 C CA  . ILE B 1 50  ? 145.375 128.163 143.199 1.00 45.94  ? 50  ILE B CA  1 
ATOM   3488 C C   . ILE B 1 50  ? 146.382 128.998 143.974 1.00 59.15  ? 50  ILE B C   1 
ATOM   3489 O O   . ILE B 1 50  ? 146.593 128.792 145.174 1.00 67.82  ? 50  ILE B O   1 
ATOM   3490 C CB  . ILE B 1 50  ? 146.071 127.101 142.335 1.00 42.92  ? 50  ILE B CB  1 
ATOM   3491 C CG1 . ILE B 1 50  ? 145.035 126.159 141.740 1.00 53.30  ? 50  ILE B CG1 1 
ATOM   3492 C CG2 . ILE B 1 50  ? 147.074 126.325 143.155 1.00 49.29  ? 50  ILE B CG2 1 
ATOM   3493 C CD1 . ILE B 1 50  ? 145.590 125.287 140.668 1.00 59.31  ? 50  ILE B CD1 1 
ATOM   3494 N N   . VAL B 1 51  ? 147.017 129.956 143.302 1.00 50.03  ? 51  VAL B N   1 
ATOM   3495 C CA  . VAL B 1 51  ? 147.958 130.834 143.987 1.00 48.31  ? 51  VAL B CA  1 
ATOM   3496 C C   . VAL B 1 51  ? 147.229 131.719 144.990 1.00 59.23  ? 51  VAL B C   1 
ATOM   3497 O O   . VAL B 1 51  ? 147.748 132.008 146.074 1.00 64.21  ? 51  VAL B O   1 
ATOM   3498 C CB  . VAL B 1 51  ? 148.755 131.659 142.963 1.00 49.91  ? 51  VAL B CB  1 
ATOM   3499 C CG1 . VAL B 1 51  ? 149.546 132.743 143.657 1.00 59.08  ? 51  VAL B CG1 1 
ATOM   3500 C CG2 . VAL B 1 51  ? 149.679 130.755 142.183 1.00 50.44  ? 51  VAL B CG2 1 
ATOM   3501 N N   . SER B 1 52  ? 146.015 132.160 144.652 1.00 53.05  ? 52  SER B N   1 
ATOM   3502 C CA  . SER B 1 52  ? 145.247 132.981 145.583 1.00 47.31  ? 52  SER B CA  1 
ATOM   3503 C C   . SER B 1 52  ? 144.906 132.213 146.851 1.00 56.49  ? 52  SER B C   1 
ATOM   3504 O O   . SER B 1 52  ? 145.014 132.753 147.957 1.00 63.37  ? 52  SER B O   1 
ATOM   3505 C CB  . SER B 1 52  ? 143.973 133.488 144.914 1.00 49.87  ? 52  SER B CB  1 
ATOM   3506 O OG  . SER B 1 52  ? 144.281 134.384 143.866 1.00 63.37  ? 52  SER B OG  1 
ATOM   3507 N N   . LEU B 1 53  ? 144.486 130.955 146.717 1.00 49.50  ? 53  LEU B N   1 
ATOM   3508 C CA  . LEU B 1 53  ? 144.152 130.181 147.906 1.00 48.52  ? 53  LEU B CA  1 
ATOM   3509 C C   . LEU B 1 53  ? 145.391 129.840 148.716 1.00 56.60  ? 53  LEU B C   1 
ATOM   3510 O O   . LEU B 1 53  ? 145.316 129.746 149.945 1.00 67.28  ? 53  LEU B O   1 
ATOM   3511 C CB  . LEU B 1 53  ? 143.403 128.903 147.538 1.00 51.19  ? 53  LEU B CB  1 
ATOM   3512 C CG  . LEU B 1 53  ? 141.879 128.999 147.472 1.00 54.24  ? 53  LEU B CG  1 
ATOM   3513 C CD1 . LEU B 1 53  ? 141.308 129.358 148.828 1.00 57.04  ? 53  LEU B CD1 1 
ATOM   3514 C CD2 . LEU B 1 53  ? 141.440 129.987 146.441 1.00 54.43  ? 53  LEU B CD2 1 
ATOM   3515 N N   . MET B 1 54  ? 146.533 129.648 148.057 1.00 54.18  ? 54  MET B N   1 
ATOM   3516 C CA  . MET B 1 54  ? 147.760 129.364 148.792 1.00 58.77  ? 54  MET B CA  1 
ATOM   3517 C C   . MET B 1 54  ? 148.136 130.527 149.696 1.00 59.44  ? 54  MET B C   1 
ATOM   3518 O O   . MET B 1 54  ? 148.605 130.323 150.821 1.00 62.53  ? 54  MET B O   1 
ATOM   3519 C CB  . MET B 1 54  ? 148.896 129.046 147.823 1.00 58.75  ? 54  MET B CB  1 
ATOM   3520 C CG  . MET B 1 54  ? 148.797 127.671 147.203 1.00 59.45  ? 54  MET B CG  1 
ATOM   3521 S SD  . MET B 1 54  ? 150.394 126.873 147.020 1.00 83.62  ? 54  MET B SD  1 
ATOM   3522 C CE  . MET B 1 54  ? 150.969 127.659 145.526 1.00 66.58  ? 54  MET B CE  1 
ATOM   3523 N N   . TYR B 1 55  ? 147.944 131.757 149.223 1.00 57.88  ? 55  TYR B N   1 
ATOM   3524 C CA  . TYR B 1 55  ? 148.214 132.910 150.072 1.00 58.62  ? 55  TYR B CA  1 
ATOM   3525 C C   . TYR B 1 55  ? 147.228 132.989 151.229 1.00 67.43  ? 55  TYR B C   1 
ATOM   3526 O O   . TYR B 1 55  ? 147.615 133.304 152.359 1.00 77.36  ? 55  TYR B O   1 
ATOM   3527 C CB  . TYR B 1 55  ? 148.173 134.195 149.255 1.00 56.68  ? 55  TYR B CB  1 
ATOM   3528 C CG  . TYR B 1 55  ? 148.463 135.418 150.084 1.00 63.85  ? 55  TYR B CG  1 
ATOM   3529 C CD1 . TYR B 1 55  ? 149.714 135.612 150.648 1.00 66.70  ? 55  TYR B CD1 1 
ATOM   3530 C CD2 . TYR B 1 55  ? 147.486 136.370 150.315 1.00 63.95  ? 55  TYR B CD2 1 
ATOM   3531 C CE1 . TYR B 1 55  ? 149.986 136.724 151.411 1.00 69.60  ? 55  TYR B CE1 1 
ATOM   3532 C CE2 . TYR B 1 55  ? 147.748 137.488 151.076 1.00 67.88  ? 55  TYR B CE2 1 
ATOM   3533 C CZ  . TYR B 1 55  ? 148.999 137.660 151.622 1.00 72.80  ? 55  TYR B CZ  1 
ATOM   3534 O OH  . TYR B 1 55  ? 149.265 138.773 152.383 1.00 72.92  ? 55  TYR B OH  1 
ATOM   3535 N N   . PHE B 1 56  ? 145.952 132.706 150.971 1.00 65.86  ? 56  PHE B N   1 
ATOM   3536 C CA  . PHE B 1 56  ? 144.934 132.799 152.008 1.00 63.44  ? 56  PHE B CA  1 
ATOM   3537 C C   . PHE B 1 56  ? 144.895 131.583 152.919 1.00 64.66  ? 56  PHE B C   1 
ATOM   3538 O O   . PHE B 1 56  ? 144.151 131.597 153.903 1.00 72.87  ? 56  PHE B O   1 
ATOM   3539 C CB  . PHE B 1 56  ? 143.555 133.001 151.382 1.00 58.16  ? 56  PHE B CB  1 
ATOM   3540 C CG  . PHE B 1 56  ? 143.357 134.361 150.795 1.00 62.43  ? 56  PHE B CG  1 
ATOM   3541 C CD1 . PHE B 1 56  ? 143.710 135.491 151.506 1.00 64.93  ? 56  PHE B CD1 1 
ATOM   3542 C CD2 . PHE B 1 56  ? 142.814 134.511 149.535 1.00 63.17  ? 56  PHE B CD2 1 
ATOM   3543 C CE1 . PHE B 1 56  ? 143.530 136.744 150.970 1.00 64.31  ? 56  PHE B CE1 1 
ATOM   3544 C CE2 . PHE B 1 56  ? 142.631 135.762 148.995 1.00 65.24  ? 56  PHE B CE2 1 
ATOM   3545 C CZ  . PHE B 1 56  ? 142.991 136.881 149.713 1.00 64.91  ? 56  PHE B CZ  1 
ATOM   3546 N N   . ALA B 1 57  ? 145.661 130.538 152.623 1.00 53.31  ? 57  ALA B N   1 
ATOM   3547 C CA  . ALA B 1 57  ? 145.685 129.359 153.473 1.00 51.75  ? 57  ALA B CA  1 
ATOM   3548 C C   . ALA B 1 57  ? 146.922 129.274 154.350 1.00 62.78  ? 57  ALA B C   1 
ATOM   3549 O O   . ALA B 1 57  ? 146.850 128.709 155.444 1.00 66.03  ? 57  ALA B O   1 
ATOM   3550 C CB  . ALA B 1 57  ? 145.589 128.088 152.626 1.00 54.15  ? 57  ALA B CB  1 
ATOM   3551 N N   . PHE B 1 58  ? 148.051 129.824 153.908 1.00 65.22  ? 58  PHE B N   1 
ATOM   3552 C CA  . PHE B 1 58  ? 149.297 129.714 154.651 1.00 67.05  ? 58  PHE B CA  1 
ATOM   3553 C C   . PHE B 1 58  ? 149.718 131.004 155.337 1.00 68.46  ? 58  PHE B C   1 
ATOM   3554 O O   . PHE B 1 58  ? 150.549 130.953 156.249 1.00 71.84  ? 58  PHE B O   1 
ATOM   3555 C CB  . PHE B 1 58  ? 150.429 129.244 153.727 1.00 59.13  ? 58  PHE B CB  1 
ATOM   3556 C CG  . PHE B 1 58  ? 150.098 128.007 152.948 1.00 59.99  ? 58  PHE B CG  1 
ATOM   3557 C CD1 . PHE B 1 58  ? 149.348 126.995 153.515 1.00 59.18  ? 58  PHE B CD1 1 
ATOM   3558 C CD2 . PHE B 1 58  ? 150.543 127.852 151.649 1.00 64.52  ? 58  PHE B CD2 1 
ATOM   3559 C CE1 . PHE B 1 58  ? 149.042 125.860 152.800 1.00 58.08  ? 58  PHE B CE1 1 
ATOM   3560 C CE2 . PHE B 1 58  ? 150.241 126.716 150.932 1.00 62.78  ? 58  PHE B CE2 1 
ATOM   3561 C CZ  . PHE B 1 58  ? 149.489 125.720 151.509 1.00 61.45  ? 58  PHE B CZ  1 
ATOM   3562 N N   . THR B 1 59  ? 149.174 132.151 154.936 1.00 64.20  ? 59  THR B N   1 
ATOM   3563 C CA  . THR B 1 59  ? 149.511 133.418 155.567 1.00 63.15  ? 59  THR B CA  1 
ATOM   3564 C C   . THR B 1 59  ? 148.389 133.998 156.408 1.00 66.17  ? 59  THR B C   1 
ATOM   3565 O O   . THR B 1 59  ? 148.664 134.755 157.339 1.00 71.64  ? 59  THR B O   1 
ATOM   3566 C CB  . THR B 1 59  ? 149.910 134.453 154.512 1.00 60.94  ? 59  THR B CB  1 
ATOM   3567 O OG1 . THR B 1 59  ? 148.787 134.730 153.668 1.00 63.87  ? 59  THR B OG1 1 
ATOM   3568 C CG2 . THR B 1 59  ? 151.053 133.931 153.668 1.00 66.99  ? 59  THR B CG2 1 
ATOM   3569 N N   . ARG B 1 60  ? 147.140 133.666 156.106 1.00 62.90  ? 60  ARG B N   1 
ATOM   3570 C CA  . ARG B 1 60  ? 146.018 134.210 156.850 1.00 64.38  ? 60  ARG B CA  1 
ATOM   3571 C C   . ARG B 1 60  ? 145.997 133.660 158.271 1.00 67.96  ? 60  ARG B C   1 
ATOM   3572 O O   . ARG B 1 60  ? 146.504 132.571 158.547 1.00 66.94  ? 60  ARG B O   1 
ATOM   3573 C CB  . ARG B 1 60  ? 144.708 133.883 156.140 1.00 62.76  ? 60  ARG B CB  1 
ATOM   3574 C CG  . ARG B 1 60  ? 143.657 134.963 156.252 1.00 68.64  ? 60  ARG B CG  1 
ATOM   3575 C CD  . ARG B 1 60  ? 142.315 134.464 155.770 1.00 64.28  ? 60  ARG B CD  1 
ATOM   3576 N NE  . ARG B 1 60  ? 141.951 133.209 156.412 1.00 60.77  ? 60  ARG B NE  1 
ATOM   3577 C CZ  . ARG B 1 60  ? 141.086 133.106 157.410 1.00 62.49  ? 60  ARG B CZ  1 
ATOM   3578 N NH1 . ARG B 1 60  ? 140.481 134.168 157.911 1.00 57.48  ? 60  ARG B NH1 1 
ATOM   3579 N NH2 . ARG B 1 60  ? 140.825 131.908 157.919 1.00 68.37  ? 60  ARG B NH2 1 
ATOM   3580 N N   . ASP B 1 61  ? 145.410 134.434 159.179 1.00 75.69  ? 61  ASP B N   1 
ATOM   3581 C CA  . ASP B 1 61  ? 145.267 134.044 160.575 1.00 74.75  ? 61  ASP B CA  1 
ATOM   3582 C C   . ASP B 1 61  ? 143.861 133.503 160.787 1.00 79.01  ? 61  ASP B C   1 
ATOM   3583 O O   . ASP B 1 61  ? 142.879 134.222 160.577 1.00 81.63  ? 61  ASP B O   1 
ATOM   3584 C CB  . ASP B 1 61  ? 145.535 135.229 161.503 1.00 74.72  ? 61  ASP B CB  1 
ATOM   3585 C CG  . ASP B 1 61  ? 145.767 134.809 162.944 1.00 80.22  ? 61  ASP B CG  1 
ATOM   3586 O OD1 . ASP B 1 61  ? 145.177 133.801 163.385 1.00 77.95  ? 61  ASP B OD1 1 
ATOM   3587 O OD2 . ASP B 1 61  ? 146.543 135.493 163.641 1.00 84.91  ? 61  ASP B OD2 1 
ATOM   3588 N N   . ASP B 1 62  ? 143.766 132.247 161.211 1.00 76.68  ? 62  ASP B N   1 
ATOM   3589 C CA  . ASP B 1 62  ? 142.491 131.567 161.398 1.00 75.02  ? 62  ASP B CA  1 
ATOM   3590 C C   . ASP B 1 62  ? 142.278 131.188 162.857 1.00 75.60  ? 62  ASP B C   1 
ATOM   3591 O O   . ASP B 1 62  ? 141.788 130.103 163.173 1.00 78.97  ? 62  ASP B O   1 
ATOM   3592 C CB  . ASP B 1 62  ? 142.396 130.337 160.500 1.00 73.43  ? 62  ASP B CB  1 
ATOM   3593 C CG  . ASP B 1 62  ? 143.644 129.487 160.540 1.00 80.95  ? 62  ASP B CG  1 
ATOM   3594 O OD1 . ASP B 1 62  ? 144.356 129.515 161.564 1.00 81.74  ? 62  ASP B OD1 1 
ATOM   3595 O OD2 . ASP B 1 62  ? 143.915 128.785 159.545 1.00 88.00  ? 62  ASP B OD2 1 
ATOM   3596 N N   . SER B 1 63  ? 142.657 132.084 163.768 1.00 78.43  ? 63  SER B N   1 
ATOM   3597 C CA  . SER B 1 63  ? 142.470 131.828 165.189 1.00 81.28  ? 63  SER B CA  1 
ATOM   3598 C C   . SER B 1 63  ? 141.054 132.144 165.654 1.00 81.56  ? 63  SER B C   1 
ATOM   3599 O O   . SER B 1 63  ? 140.615 131.615 166.680 1.00 83.15  ? 63  SER B O   1 
ATOM   3600 C CB  . SER B 1 63  ? 143.481 132.634 166.003 1.00 83.10  ? 63  SER B CB  1 
ATOM   3601 O OG  . SER B 1 63  ? 143.417 134.009 165.671 1.00 84.38  ? 63  SER B OG  1 
ATOM   3602 N N   . VAL B 1 64  ? 140.334 132.998 164.936 1.00 77.68  ? 64  VAL B N   1 
ATOM   3603 C CA  . VAL B 1 64  ? 138.982 133.397 165.319 1.00 79.14  ? 64  VAL B CA  1 
ATOM   3604 C C   . VAL B 1 64  ? 137.998 132.465 164.619 1.00 79.51  ? 64  VAL B C   1 
ATOM   3605 O O   . VAL B 1 64  ? 137.910 132.497 163.383 1.00 80.61  ? 64  VAL B O   1 
ATOM   3606 C CB  . VAL B 1 64  ? 138.704 134.859 164.954 1.00 78.30  ? 64  VAL B CB  1 
ATOM   3607 C CG1 . VAL B 1 64  ? 137.550 135.396 165.780 1.00 75.34  ? 64  VAL B CG1 1 
ATOM   3608 C CG2 . VAL B 1 64  ? 139.949 135.701 165.163 1.00 77.03  ? 64  VAL B CG2 1 
ATOM   3609 N N   . PRO B 1 65  ? 137.259 131.629 165.353 1.00 77.76  ? 65  PRO B N   1 
ATOM   3610 C CA  . PRO B 1 65  ? 136.311 130.721 164.687 1.00 73.22  ? 65  PRO B CA  1 
ATOM   3611 C C   . PRO B 1 65  ? 135.207 131.431 163.925 1.00 75.43  ? 65  PRO B C   1 
ATOM   3612 O O   . PRO B 1 65  ? 134.775 130.941 162.877 1.00 79.89  ? 65  PRO B O   1 
ATOM   3613 C CB  . PRO B 1 65  ? 135.750 129.894 165.852 1.00 73.58  ? 65  PRO B CB  1 
ATOM   3614 C CG  . PRO B 1 65  ? 136.770 130.007 166.929 1.00 75.65  ? 65  PRO B CG  1 
ATOM   3615 C CD  . PRO B 1 65  ? 137.330 131.386 166.801 1.00 77.56  ? 65  PRO B CD  1 
ATOM   3616 N N   . GLU B 1 66  ? 134.728 132.569 164.426 1.00 79.77  ? 66  GLU B N   1 
ATOM   3617 C CA  . GLU B 1 66  ? 133.586 133.221 163.793 1.00 82.47  ? 66  GLU B CA  1 
ATOM   3618 C C   . GLU B 1 66  ? 133.983 133.915 162.497 1.00 80.79  ? 66  GLU B C   1 
ATOM   3619 O O   . GLU B 1 66  ? 133.256 133.838 161.501 1.00 78.95  ? 66  GLU B O   1 
ATOM   3620 C CB  . GLU B 1 66  ? 132.949 134.215 164.761 1.00 81.57  ? 66  GLU B CB  1 
ATOM   3621 C CG  . GLU B 1 66  ? 131.887 135.092 164.129 1.00 81.87  ? 66  GLU B CG  1 
ATOM   3622 C CD  . GLU B 1 66  ? 131.549 136.295 164.983 1.00 89.82  ? 66  GLU B CD  1 
ATOM   3623 O OE1 . GLU B 1 66  ? 130.837 137.194 164.489 1.00 91.57  ? 66  GLU B OE1 1 
ATOM   3624 O OE2 . GLU B 1 66  ? 131.996 136.338 166.148 1.00 86.37  ? 66  GLU B OE2 1 
ATOM   3625 N N   . ASP B 1 67  ? 135.125 134.603 162.488 1.00 78.14  ? 67  ASP B N   1 
ATOM   3626 C CA  . ASP B 1 67  ? 135.538 135.325 161.292 1.00 70.19  ? 67  ASP B CA  1 
ATOM   3627 C C   . ASP B 1 67  ? 136.030 134.396 160.195 1.00 74.31  ? 67  ASP B C   1 
ATOM   3628 O O   . ASP B 1 67  ? 136.094 134.810 159.035 1.00 77.26  ? 67  ASP B O   1 
ATOM   3629 C CB  . ASP B 1 67  ? 136.623 136.344 161.633 1.00 73.95  ? 67  ASP B CB  1 
ATOM   3630 C CG  . ASP B 1 67  ? 136.102 137.483 162.485 1.00 81.96  ? 67  ASP B CG  1 
ATOM   3631 O OD1 . ASP B 1 67  ? 135.877 137.270 163.695 1.00 80.16  ? 67  ASP B OD1 1 
ATOM   3632 O OD2 . ASP B 1 67  ? 135.911 138.591 161.944 1.00 84.41  ? 67  ASP B OD2 1 
ATOM   3633 N N   . ASN B 1 68  ? 136.390 133.159 160.535 1.00 71.26  ? 68  ASN B N   1 
ATOM   3634 C CA  . ASN B 1 68  ? 136.768 132.193 159.510 1.00 63.44  ? 68  ASN B CA  1 
ATOM   3635 C C   . ASN B 1 68  ? 135.574 131.812 158.651 1.00 68.78  ? 68  ASN B C   1 
ATOM   3636 O O   . ASN B 1 68  ? 135.701 131.660 157.432 1.00 72.83  ? 68  ASN B O   1 
ATOM   3637 C CB  . ASN B 1 68  ? 137.370 130.954 160.161 1.00 59.81  ? 68  ASN B CB  1 
ATOM   3638 C CG  . ASN B 1 68  ? 138.821 131.134 160.497 1.00 70.22  ? 68  ASN B CG  1 
ATOM   3639 O OD1 . ASN B 1 68  ? 139.516 131.932 159.874 1.00 71.66  ? 68  ASN B OD1 1 
ATOM   3640 N ND2 . ASN B 1 68  ? 139.291 130.400 161.494 1.00 72.44  ? 68  ASN B ND2 1 
ATOM   3641 N N   . ILE B 1 69  ? 134.408 131.644 159.272 1.00 67.89  ? 69  ILE B N   1 
ATOM   3642 C CA  . ILE B 1 69  ? 133.214 131.280 158.520 1.00 65.09  ? 69  ILE B CA  1 
ATOM   3643 C C   . ILE B 1 69  ? 132.796 132.417 157.600 1.00 62.60  ? 69  ILE B C   1 
ATOM   3644 O O   . ILE B 1 69  ? 132.328 132.186 156.481 1.00 70.65  ? 69  ILE B O   1 
ATOM   3645 C CB  . ILE B 1 69  ? 132.084 130.881 159.484 1.00 60.26  ? 69  ILE B CB  1 
ATOM   3646 C CG1 . ILE B 1 69  ? 132.499 129.661 160.298 1.00 61.11  ? 69  ILE B CG1 1 
ATOM   3647 C CG2 . ILE B 1 69  ? 130.811 130.592 158.725 1.00 58.59  ? 69  ILE B CG2 1 
ATOM   3648 C CD1 . ILE B 1 69  ? 131.512 129.293 161.361 1.00 67.23  ? 69  ILE B CD1 1 
ATOM   3649 N N   . TRP B 1 70  ? 132.953 133.661 158.051 1.00 61.08  ? 70  TRP B N   1 
ATOM   3650 C CA  . TRP B 1 70  ? 132.561 134.788 157.214 1.00 61.74  ? 70  TRP B CA  1 
ATOM   3651 C C   . TRP B 1 70  ? 133.449 134.895 155.982 1.00 68.72  ? 70  TRP B C   1 
ATOM   3652 O O   . TRP B 1 70  ? 132.952 134.991 154.856 1.00 74.45  ? 70  TRP B O   1 
ATOM   3653 C CB  . TRP B 1 70  ? 132.601 136.086 158.015 1.00 62.80  ? 70  TRP B CB  1 
ATOM   3654 C CG  . TRP B 1 70  ? 132.227 137.272 157.194 1.00 66.33  ? 70  TRP B CG  1 
ATOM   3655 C CD1 . TRP B 1 70  ? 132.976 138.386 156.980 1.00 65.04  ? 70  TRP B CD1 1 
ATOM   3656 C CD2 . TRP B 1 70  ? 131.007 137.463 156.469 1.00 71.98  ? 70  TRP B CD2 1 
ATOM   3657 N NE1 . TRP B 1 70  ? 132.302 139.260 156.167 1.00 68.20  ? 70  TRP B NE1 1 
ATOM   3658 C CE2 . TRP B 1 70  ? 131.089 138.716 155.841 1.00 68.60  ? 70  TRP B CE2 1 
ATOM   3659 C CE3 . TRP B 1 70  ? 129.853 136.695 156.292 1.00 68.56  ? 70  TRP B CE3 1 
ATOM   3660 C CZ2 . TRP B 1 70  ? 130.064 139.218 155.050 1.00 67.89  ? 70  TRP B CZ2 1 
ATOM   3661 C CZ3 . TRP B 1 70  ? 128.840 137.195 155.508 1.00 66.91  ? 70  TRP B CZ3 1 
ATOM   3662 C CH2 . TRP B 1 70  ? 128.950 138.444 154.897 1.00 70.37  ? 70  TRP B CH2 1 
ATOM   3663 N N   . ARG B 1 71  ? 134.769 134.876 156.173 1.00 64.71  ? 71  ARG B N   1 
ATOM   3664 C CA  . ARG B 1 71  ? 135.667 134.961 155.028 1.00 59.68  ? 71  ARG B CA  1 
ATOM   3665 C C   . ARG B 1 71  ? 135.541 133.741 154.127 1.00 66.29  ? 71  ARG B C   1 
ATOM   3666 O O   . ARG B 1 71  ? 135.721 133.853 152.911 1.00 68.11  ? 71  ARG B O   1 
ATOM   3667 C CB  . ARG B 1 71  ? 137.108 135.137 155.494 1.00 55.14  ? 71  ARG B CB  1 
ATOM   3668 C CG  . ARG B 1 71  ? 137.474 136.572 155.830 1.00 62.77  ? 71  ARG B CG  1 
ATOM   3669 C CD  . ARG B 1 71  ? 138.887 136.659 156.375 1.00 74.73  ? 71  ARG B CD  1 
ATOM   3670 N NE  . ARG B 1 71  ? 139.338 138.033 156.568 1.00 81.42  ? 71  ARG B NE  1 
ATOM   3671 C CZ  . ARG B 1 71  ? 140.510 138.501 156.159 1.00 78.05  ? 71  ARG B CZ  1 
ATOM   3672 N NH1 . ARG B 1 71  ? 141.372 137.736 155.509 1.00 68.41  ? 71  ARG B NH1 1 
ATOM   3673 N NH2 . ARG B 1 71  ? 140.827 139.768 156.409 1.00 74.88  ? 71  ARG B NH2 1 
ATOM   3674 N N   . GLY B 1 72  ? 135.234 132.576 154.695 1.00 60.98  ? 72  GLY B N   1 
ATOM   3675 C CA  . GLY B 1 72  ? 134.984 131.410 153.866 1.00 58.21  ? 72  GLY B CA  1 
ATOM   3676 C C   . GLY B 1 72  ? 133.753 131.572 152.995 1.00 65.61  ? 72  GLY B C   1 
ATOM   3677 O O   . GLY B 1 72  ? 133.746 131.166 151.832 1.00 66.02  ? 72  GLY B O   1 
ATOM   3678 N N   . ILE B 1 73  ? 132.693 132.162 153.549 1.00 61.43  ? 73  ILE B N   1 
ATOM   3679 C CA  . ILE B 1 73  ? 131.479 132.404 152.776 1.00 50.44  ? 73  ILE B CA  1 
ATOM   3680 C C   . ILE B 1 73  ? 131.749 133.395 151.653 1.00 56.07  ? 73  ILE B C   1 
ATOM   3681 O O   . ILE B 1 73  ? 131.269 133.223 150.528 1.00 67.19  ? 73  ILE B O   1 
ATOM   3682 C CB  . ILE B 1 73  ? 130.350 132.884 153.702 1.00 47.82  ? 73  ILE B CB  1 
ATOM   3683 C CG1 . ILE B 1 73  ? 129.803 131.712 154.509 1.00 57.05  ? 73  ILE B CG1 1 
ATOM   3684 C CG2 . ILE B 1 73  ? 129.239 133.525 152.906 1.00 59.07  ? 73  ILE B CG2 1 
ATOM   3685 C CD1 . ILE B 1 73  ? 128.925 132.125 155.652 1.00 59.22  ? 73  ILE B CD1 1 
ATOM   3686 N N   . LEU B 1 74  ? 132.517 134.448 151.937 1.00 51.82  ? 74  LEU B N   1 
ATOM   3687 C CA  . LEU B 1 74  ? 132.883 135.399 150.893 1.00 51.88  ? 74  LEU B CA  1 
ATOM   3688 C C   . LEU B 1 74  ? 133.719 134.734 149.810 1.00 56.53  ? 74  LEU B C   1 
ATOM   3689 O O   . LEU B 1 74  ? 133.546 135.017 148.620 1.00 61.98  ? 74  LEU B O   1 
ATOM   3690 C CB  . LEU B 1 74  ? 133.640 136.576 151.499 1.00 51.93  ? 74  LEU B CB  1 
ATOM   3691 C CG  . LEU B 1 74  ? 132.854 137.415 152.496 1.00 54.62  ? 74  LEU B CG  1 
ATOM   3692 C CD1 . LEU B 1 74  ? 133.624 138.670 152.844 1.00 58.27  ? 74  LEU B CD1 1 
ATOM   3693 C CD2 . LEU B 1 74  ? 131.501 137.757 151.919 1.00 59.77  ? 74  LEU B CD2 1 
ATOM   3694 N N   . SER B 1 75  ? 134.643 133.858 150.204 1.00 45.33  ? 75  SER B N   1 
ATOM   3695 C CA  . SER B 1 75  ? 135.479 133.178 149.223 1.00 50.41  ? 75  SER B CA  1 
ATOM   3696 C C   . SER B 1 75  ? 134.663 132.232 148.353 1.00 51.41  ? 75  SER B C   1 
ATOM   3697 O O   . SER B 1 75  ? 134.887 132.151 147.142 1.00 59.46  ? 75  SER B O   1 
ATOM   3698 C CB  . SER B 1 75  ? 136.597 132.420 149.927 1.00 58.13  ? 75  SER B CB  1 
ATOM   3699 O OG  . SER B 1 75  ? 137.427 131.773 148.985 1.00 67.31  ? 75  SER B OG  1 
ATOM   3700 N N   . VAL B 1 76  ? 133.719 131.504 148.950 1.00 41.72  ? 76  VAL B N   1 
ATOM   3701 C CA  . VAL B 1 76  ? 132.870 130.609 148.169 1.00 41.40  ? 76  VAL B CA  1 
ATOM   3702 C C   . VAL B 1 76  ? 132.039 131.403 147.173 1.00 42.48  ? 76  VAL B C   1 
ATOM   3703 O O   . VAL B 1 76  ? 131.871 130.998 146.018 1.00 54.83  ? 76  VAL B O   1 
ATOM   3704 C CB  . VAL B 1 76  ? 131.985 129.765 149.102 1.00 46.40  ? 76  VAL B CB  1 
ATOM   3705 C CG1 . VAL B 1 76  ? 130.743 129.294 148.376 1.00 48.79  ? 76  VAL B CG1 1 
ATOM   3706 C CG2 . VAL B 1 76  ? 132.766 128.591 149.644 1.00 43.52  ? 76  VAL B CG2 1 
ATOM   3707 N N   . ILE B 1 77  ? 131.507 132.547 147.602 1.00 49.12  ? 77  ILE B N   1 
ATOM   3708 C CA  . ILE B 1 77  ? 130.738 133.396 146.699 1.00 51.20  ? 77  ILE B CA  1 
ATOM   3709 C C   . ILE B 1 77  ? 131.625 133.943 145.591 1.00 50.27  ? 77  ILE B C   1 
ATOM   3710 O O   . ILE B 1 77  ? 131.225 133.984 144.423 1.00 61.45  ? 77  ILE B O   1 
ATOM   3711 C CB  . ILE B 1 77  ? 130.052 134.524 147.487 1.00 45.03  ? 77  ILE B CB  1 
ATOM   3712 C CG1 . ILE B 1 77  ? 128.822 133.985 148.212 1.00 53.33  ? 77  ILE B CG1 1 
ATOM   3713 C CG2 . ILE B 1 77  ? 129.665 135.655 146.567 1.00 38.90  ? 77  ILE B CG2 1 
ATOM   3714 C CD1 . ILE B 1 77  ? 128.167 134.993 149.105 1.00 53.63  ? 77  ILE B CD1 1 
ATOM   3715 N N   . PHE B 1 78  ? 132.840 134.373 145.933 1.00 38.23  ? 78  PHE B N   1 
ATOM   3716 C CA  . PHE B 1 78  ? 133.736 134.910 144.915 1.00 38.88  ? 78  PHE B CA  1 
ATOM   3717 C C   . PHE B 1 78  ? 134.101 133.853 143.887 1.00 42.42  ? 78  PHE B C   1 
ATOM   3718 O O   . PHE B 1 78  ? 134.128 134.134 142.685 1.00 58.07  ? 78  PHE B O   1 
ATOM   3719 C CB  . PHE B 1 78  ? 135.000 135.473 145.556 1.00 39.74  ? 78  PHE B CB  1 
ATOM   3720 C CG  . PHE B 1 78  ? 136.063 135.835 144.564 1.00 42.38  ? 78  PHE B CG  1 
ATOM   3721 C CD1 . PHE B 1 78  ? 135.793 136.699 143.526 1.00 51.88  ? 78  PHE B CD1 1 
ATOM   3722 C CD2 . PHE B 1 78  ? 137.333 135.308 144.669 1.00 51.33  ? 78  PHE B CD2 1 
ATOM   3723 C CE1 . PHE B 1 78  ? 136.767 137.030 142.615 1.00 51.88  ? 78  PHE B CE1 1 
ATOM   3724 C CE2 . PHE B 1 78  ? 138.310 135.639 143.758 1.00 52.60  ? 78  PHE B CE2 1 
ATOM   3725 C CZ  . PHE B 1 78  ? 138.026 136.499 142.731 1.00 44.81  ? 78  PHE B CZ  1 
ATOM   3726 N N   . PHE B 1 79  ? 134.382 132.634 144.333 1.00 41.68  ? 79  PHE B N   1 
ATOM   3727 C CA  . PHE B 1 79  ? 134.807 131.575 143.431 1.00 43.34  ? 79  PHE B CA  1 
ATOM   3728 C C   . PHE B 1 79  ? 133.644 130.820 142.813 1.00 37.67  ? 79  PHE B C   1 
ATOM   3729 O O   . PHE B 1 79  ? 133.873 129.898 142.029 1.00 38.42  ? 79  PHE B O   1 
ATOM   3730 C CB  . PHE B 1 79  ? 135.745 130.613 144.157 1.00 40.20  ? 79  PHE B CB  1 
ATOM   3731 C CG  . PHE B 1 79  ? 137.115 131.172 144.362 1.00 43.80  ? 79  PHE B CG  1 
ATOM   3732 C CD1 . PHE B 1 79  ? 137.982 131.306 143.300 1.00 39.61  ? 79  PHE B CD1 1 
ATOM   3733 C CD2 . PHE B 1 79  ? 137.525 131.598 145.608 1.00 51.64  ? 79  PHE B CD2 1 
ATOM   3734 C CE1 . PHE B 1 79  ? 139.234 131.836 143.481 1.00 50.09  ? 79  PHE B CE1 1 
ATOM   3735 C CE2 . PHE B 1 79  ? 138.779 132.130 145.791 1.00 45.67  ? 79  PHE B CE2 1 
ATOM   3736 C CZ  . PHE B 1 79  ? 139.632 132.251 144.724 1.00 51.62  ? 79  PHE B CZ  1 
ATOM   3737 N N   . PHE B 1 80  ? 132.408 131.174 143.157 1.00 35.55  ? 80  PHE B N   1 
ATOM   3738 C CA  . PHE B 1 80  ? 131.275 130.736 142.354 1.00 36.60  ? 80  PHE B CA  1 
ATOM   3739 C C   . PHE B 1 80  ? 131.033 131.677 141.187 1.00 39.34  ? 80  PHE B C   1 
ATOM   3740 O O   . PHE B 1 80  ? 130.513 131.253 140.151 1.00 51.33  ? 80  PHE B O   1 
ATOM   3741 C CB  . PHE B 1 80  ? 130.013 130.633 143.206 1.00 37.83  ? 80  PHE B CB  1 
ATOM   3742 C CG  . PHE B 1 80  ? 128.864 129.983 142.498 1.00 39.52  ? 80  PHE B CG  1 
ATOM   3743 C CD1 . PHE B 1 80  ? 128.847 128.621 142.289 1.00 38.33  ? 80  PHE B CD1 1 
ATOM   3744 C CD2 . PHE B 1 80  ? 127.805 130.733 142.039 1.00 44.58  ? 80  PHE B CD2 1 
ATOM   3745 C CE1 . PHE B 1 80  ? 127.798 128.020 141.641 1.00 40.67  ? 80  PHE B CE1 1 
ATOM   3746 C CE2 . PHE B 1 80  ? 126.752 130.133 141.389 1.00 47.14  ? 80  PHE B CE2 1 
ATOM   3747 C CZ  . PHE B 1 80  ? 126.749 128.777 141.192 1.00 44.05  ? 80  PHE B CZ  1 
ATOM   3748 N N   . LEU B 1 81  ? 131.390 132.952 141.338 1.00 36.28  ? 81  LEU B N   1 
ATOM   3749 C CA  . LEU B 1 81  ? 131.345 133.868 140.207 1.00 36.68  ? 81  LEU B CA  1 
ATOM   3750 C C   . LEU B 1 81  ? 132.354 133.466 139.142 1.00 42.46  ? 81  LEU B C   1 
ATOM   3751 O O   . LEU B 1 81  ? 132.060 133.527 137.944 1.00 54.32  ? 81  LEU B O   1 
ATOM   3752 C CB  . LEU B 1 81  ? 131.603 135.296 140.680 1.00 38.27  ? 81  LEU B CB  1 
ATOM   3753 C CG  . LEU B 1 81  ? 130.626 135.865 141.706 1.00 41.93  ? 81  LEU B CG  1 
ATOM   3754 C CD1 . LEU B 1 81  ? 130.762 137.368 141.780 1.00 46.08  ? 81  LEU B CD1 1 
ATOM   3755 C CD2 . LEU B 1 81  ? 129.206 135.479 141.371 1.00 42.79  ? 81  LEU B CD2 1 
ATOM   3756 N N   . ILE B 1 82  ? 133.550 133.051 139.560 1.00 38.02  ? 82  ILE B N   1 
ATOM   3757 C CA  . ILE B 1 82  ? 134.573 132.628 138.611 1.00 36.84  ? 82  ILE B CA  1 
ATOM   3758 C C   . ILE B 1 82  ? 134.131 131.373 137.870 1.00 46.04  ? 82  ILE B C   1 
ATOM   3759 O O   . ILE B 1 82  ? 134.364 131.235 136.665 1.00 50.51  ? 82  ILE B O   1 
ATOM   3760 C CB  . ILE B 1 82  ? 135.912 132.430 139.341 1.00 40.03  ? 82  ILE B CB  1 
ATOM   3761 C CG1 . ILE B 1 82  ? 136.678 133.749 139.390 1.00 41.94  ? 82  ILE B CG1 1 
ATOM   3762 C CG2 . ILE B 1 82  ? 136.742 131.344 138.686 1.00 37.39  ? 82  ILE B CG2 1 
ATOM   3763 C CD1 . ILE B 1 82  ? 137.954 133.674 140.180 1.00 50.06  ? 82  ILE B CD1 1 
ATOM   3764 N N   . ILE B 1 83  ? 133.490 130.439 138.572 1.00 50.16  ? 83  ILE B N   1 
ATOM   3765 C CA  . ILE B 1 83  ? 132.899 129.285 137.902 1.00 43.75  ? 83  ILE B CA  1 
ATOM   3766 C C   . ILE B 1 83  ? 131.770 129.726 136.981 1.00 43.54  ? 83  ILE B C   1 
ATOM   3767 O O   . ILE B 1 83  ? 131.625 129.218 135.864 1.00 54.17  ? 83  ILE B O   1 
ATOM   3768 C CB  . ILE B 1 83  ? 132.417 128.253 138.937 1.00 45.14  ? 83  ILE B CB  1 
ATOM   3769 C CG1 . ILE B 1 83  ? 133.548 127.292 139.288 1.00 44.49  ? 83  ILE B CG1 1 
ATOM   3770 C CG2 . ILE B 1 83  ? 131.214 127.494 138.419 1.00 45.86  ? 83  ILE B CG2 1 
ATOM   3771 C CD1 . ILE B 1 83  ? 133.842 126.293 138.205 1.00 46.53  ? 83  ILE B CD1 1 
ATOM   3772 N N   . SER B 1 84  ? 130.956 130.682 137.431 1.00 41.82  ? 84  SER B N   1 
ATOM   3773 C CA  . SER B 1 84  ? 129.855 131.166 136.605 1.00 45.71  ? 84  SER B CA  1 
ATOM   3774 C C   . SER B 1 84  ? 130.357 131.848 135.342 1.00 47.74  ? 84  SER B C   1 
ATOM   3775 O O   . SER B 1 84  ? 129.684 131.803 134.308 1.00 50.42  ? 84  SER B O   1 
ATOM   3776 C CB  . SER B 1 84  ? 128.978 132.122 137.406 1.00 40.12  ? 84  SER B CB  1 
ATOM   3777 O OG  . SER B 1 84  ? 129.576 133.397 137.488 1.00 53.16  ? 84  SER B OG  1 
ATOM   3778 N N   . VAL B 1 85  ? 131.524 132.490 135.404 1.00 40.77  ? 85  VAL B N   1 
ATOM   3779 C CA  . VAL B 1 85  ? 132.114 133.075 134.205 1.00 38.78  ? 85  VAL B CA  1 
ATOM   3780 C C   . VAL B 1 85  ? 132.483 131.986 133.209 1.00 45.32  ? 85  VAL B C   1 
ATOM   3781 O O   . VAL B 1 85  ? 132.332 132.157 131.994 1.00 54.11  ? 85  VAL B O   1 
ATOM   3782 C CB  . VAL B 1 85  ? 133.331 133.938 134.583 1.00 37.11  ? 85  VAL B CB  1 
ATOM   3783 C CG1 . VAL B 1 85  ? 134.186 134.216 133.373 1.00 43.94  ? 85  VAL B CG1 1 
ATOM   3784 C CG2 . VAL B 1 85  ? 132.876 135.232 135.197 1.00 39.23  ? 85  VAL B CG2 1 
ATOM   3785 N N   . LEU B 1 86  ? 132.961 130.848 133.704 1.00 50.35  ? 86  LEU B N   1 
ATOM   3786 C CA  . LEU B 1 86  ? 133.416 129.779 132.827 1.00 54.27  ? 86  LEU B CA  1 
ATOM   3787 C C   . LEU B 1 86  ? 132.266 128.993 132.211 1.00 54.48  ? 86  LEU B C   1 
ATOM   3788 O O   . LEU B 1 86  ? 132.382 128.543 131.068 1.00 60.35  ? 86  LEU B O   1 
ATOM   3789 C CB  . LEU B 1 86  ? 134.336 128.832 133.596 1.00 51.93  ? 86  LEU B CB  1 
ATOM   3790 C CG  . LEU B 1 86  ? 135.653 129.421 134.097 1.00 44.72  ? 86  LEU B CG  1 
ATOM   3791 C CD1 . LEU B 1 86  ? 136.437 128.373 134.842 1.00 44.76  ? 86  LEU B CD1 1 
ATOM   3792 C CD2 . LEU B 1 86  ? 136.465 129.957 132.947 1.00 49.15  ? 86  LEU B CD2 1 
ATOM   3793 N N   . ALA B 1 87  ? 131.163 128.814 132.930 1.00 45.37  ? 87  ALA B N   1 
ATOM   3794 C CA  . ALA B 1 87  ? 130.146 127.857 132.509 1.00 47.11  ? 87  ALA B CA  1 
ATOM   3795 C C   . ALA B 1 87  ? 128.774 128.458 132.258 1.00 50.70  ? 87  ALA B C   1 
ATOM   3796 O O   . ALA B 1 87  ? 128.109 128.066 131.298 1.00 58.23  ? 87  ALA B O   1 
ATOM   3797 C CB  . ALA B 1 87  ? 130.018 126.745 133.554 1.00 43.46  ? 87  ALA B CB  1 
ATOM   3798 N N   . PHE B 1 88  ? 128.318 129.385 133.092 1.00 46.12  ? 88  PHE B N   1 
ATOM   3799 C CA  . PHE B 1 88  ? 126.929 129.808 133.033 1.00 44.89  ? 88  PHE B CA  1 
ATOM   3800 C C   . PHE B 1 88  ? 126.675 130.714 131.828 1.00 54.13  ? 88  PHE B C   1 
ATOM   3801 O O   . PHE B 1 88  ? 127.578 131.411 131.363 1.00 65.29  ? 88  PHE B O   1 
ATOM   3802 C CB  . PHE B 1 88  ? 126.538 130.525 134.319 1.00 38.73  ? 88  PHE B CB  1 
ATOM   3803 C CG  . PHE B 1 88  ? 126.176 129.595 135.438 1.00 44.76  ? 88  PHE B CG  1 
ATOM   3804 C CD1 . PHE B 1 88  ? 125.353 128.514 135.211 1.00 54.33  ? 88  PHE B CD1 1 
ATOM   3805 C CD2 . PHE B 1 88  ? 126.638 129.812 136.715 1.00 44.19  ? 88  PHE B CD2 1 
ATOM   3806 C CE1 . PHE B 1 88  ? 125.016 127.662 136.232 1.00 50.78  ? 88  PHE B CE1 1 
ATOM   3807 C CE2 . PHE B 1 88  ? 126.304 128.965 137.738 1.00 47.26  ? 88  PHE B CE2 1 
ATOM   3808 C CZ  . PHE B 1 88  ? 125.491 127.892 137.498 1.00 47.10  ? 88  PHE B CZ  1 
ATOM   3809 N N   . PRO B 1 89  ? 125.455 130.707 131.297 1.00 49.22  ? 89  PRO B N   1 
ATOM   3810 C CA  . PRO B 1 89  ? 125.138 131.544 130.137 1.00 46.72  ? 89  PRO B CA  1 
ATOM   3811 C C   . PRO B 1 89  ? 124.989 133.012 130.505 1.00 55.17  ? 89  PRO B C   1 
ATOM   3812 O O   . PRO B 1 89  ? 124.746 133.374 131.655 1.00 57.89  ? 89  PRO B O   1 
ATOM   3813 C CB  . PRO B 1 89  ? 123.807 130.968 129.649 1.00 52.28  ? 89  PRO B CB  1 
ATOM   3814 C CG  . PRO B 1 89  ? 123.204 130.375 130.853 1.00 53.16  ? 89  PRO B CG  1 
ATOM   3815 C CD  . PRO B 1 89  ? 124.339 129.815 131.645 1.00 49.64  ? 89  PRO B CD  1 
ATOM   3816 N N   . ASN B 1 90  ? 125.122 133.863 129.486 1.00 59.54  ? 90  ASN B N   1 
ATOM   3817 C CA  . ASN B 1 90  ? 125.165 135.307 129.680 1.00 56.40  ? 90  ASN B CA  1 
ATOM   3818 C C   . ASN B 1 90  ? 123.891 136.014 129.229 1.00 57.56  ? 90  ASN B C   1 
ATOM   3819 O O   . ASN B 1 90  ? 123.907 137.230 129.026 1.00 62.62  ? 90  ASN B O   1 
ATOM   3820 C CB  . ASN B 1 90  ? 126.380 135.902 128.968 1.00 55.79  ? 90  ASN B CB  1 
ATOM   3821 C CG  . ASN B 1 90  ? 126.243 135.889 127.466 1.00 55.11  ? 90  ASN B CG  1 
ATOM   3822 O OD1 . ASN B 1 90  ? 125.603 136.757 126.882 1.00 51.44  ? 90  ASN B OD1 1 
ATOM   3823 N ND2 . ASN B 1 90  ? 126.856 134.902 126.828 1.00 63.55  ? 90  ASN B ND2 1 
ATOM   3824 N N   . GLY B 1 91  ? 122.790 135.288 129.069 1.00 53.94  ? 91  GLY B N   1 
ATOM   3825 C CA  . GLY B 1 91  ? 121.518 135.907 128.779 1.00 51.73  ? 91  GLY B CA  1 
ATOM   3826 C C   . GLY B 1 91  ? 121.461 136.517 127.395 1.00 52.11  ? 91  GLY B C   1 
ATOM   3827 O O   . GLY B 1 91  ? 122.270 136.203 126.520 1.00 60.73  ? 91  GLY B O   1 
ATOM   3828 N N   . PRO B 1 92  ? 120.497 137.407 127.168 1.00 52.47  ? 92  PRO B N   1 
ATOM   3829 C CA  . PRO B 1 92  ? 120.387 138.093 125.876 1.00 58.35  ? 92  PRO B CA  1 
ATOM   3830 C C   . PRO B 1 92  ? 121.239 139.345 125.749 1.00 64.13  ? 92  PRO B C   1 
ATOM   3831 O O   . PRO B 1 92  ? 121.083 140.073 124.765 1.00 67.93  ? 92  PRO B O   1 
ATOM   3832 C CB  . PRO B 1 92  ? 118.902 138.463 125.840 1.00 58.93  ? 92  PRO B CB  1 
ATOM   3833 C CG  . PRO B 1 92  ? 118.578 138.740 127.259 1.00 58.74  ? 92  PRO B CG  1 
ATOM   3834 C CD  . PRO B 1 92  ? 119.459 137.856 128.108 1.00 52.29  ? 92  PRO B CD  1 
ATOM   3835 N N   . PHE B 1 93  ? 122.117 139.609 126.707 1.00 55.74  ? 93  PHE B N   1 
ATOM   3836 C CA  . PHE B 1 93  ? 122.883 140.840 126.764 1.00 52.85  ? 93  PHE B CA  1 
ATOM   3837 C C   . PHE B 1 93  ? 124.357 140.550 126.522 1.00 63.79  ? 93  PHE B C   1 
ATOM   3838 O O   . PHE B 1 93  ? 124.871 139.498 126.907 1.00 69.23  ? 93  PHE B O   1 
ATOM   3839 C CB  . PHE B 1 93  ? 122.703 141.526 128.117 1.00 49.82  ? 93  PHE B CB  1 
ATOM   3840 C CG  . PHE B 1 93  ? 121.329 142.082 128.334 1.00 54.10  ? 93  PHE B CG  1 
ATOM   3841 C CD1 . PHE B 1 93  ? 120.468 142.266 127.274 1.00 58.37  ? 93  PHE B CD1 1 
ATOM   3842 C CD2 . PHE B 1 93  ? 120.901 142.425 129.596 1.00 58.66  ? 93  PHE B CD2 1 
ATOM   3843 C CE1 . PHE B 1 93  ? 119.207 142.777 127.469 1.00 52.98  ? 93  PHE B CE1 1 
ATOM   3844 C CE2 . PHE B 1 93  ? 119.642 142.939 129.794 1.00 58.67  ? 93  PHE B CE2 1 
ATOM   3845 C CZ  . PHE B 1 93  ? 118.796 143.115 128.727 1.00 57.52  ? 93  PHE B CZ  1 
ATOM   3846 N N   . THR B 1 94  ? 125.034 141.497 125.873 1.00 70.35  ? 94  THR B N   1 
ATOM   3847 C CA  . THR B 1 94  ? 126.442 141.313 125.545 1.00 66.08  ? 94  THR B CA  1 
ATOM   3848 C C   . THR B 1 94  ? 127.273 142.563 125.802 1.00 68.29  ? 94  THR B C   1 
ATOM   3849 O O   . THR B 1 94  ? 128.371 142.685 125.248 1.00 79.17  ? 94  THR B O   1 
ATOM   3850 C CB  . THR B 1 94  ? 126.611 140.897 124.088 1.00 68.56  ? 94  THR B CB  1 
ATOM   3851 O OG1 . THR B 1 94  ? 128.000 140.926 123.745 1.00 72.32  ? 94  THR B OG1 1 
ATOM   3852 C CG2 . THR B 1 94  ? 125.854 141.843 123.176 1.00 69.16  ? 94  THR B CG2 1 
ATOM   3853 N N   . ARG B 1 95  ? 126.783 143.497 126.607 1.00 60.01  ? 95  ARG B N   1 
ATOM   3854 C CA  . ARG B 1 95  ? 127.562 144.656 127.006 1.00 58.47  ? 95  ARG B CA  1 
ATOM   3855 C C   . ARG B 1 95  ? 127.438 144.859 128.507 1.00 66.87  ? 95  ARG B C   1 
ATOM   3856 O O   . ARG B 1 95  ? 126.401 144.541 129.095 1.00 73.85  ? 95  ARG B O   1 
ATOM   3857 C CB  . ARG B 1 95  ? 127.099 145.924 126.278 1.00 57.78  ? 95  ARG B CB  1 
ATOM   3858 C CG  . ARG B 1 95  ? 127.630 146.081 124.865 1.00 64.85  ? 95  ARG B CG  1 
ATOM   3859 C CD  . ARG B 1 95  ? 127.564 147.537 124.456 1.00 64.98  ? 95  ARG B CD  1 
ATOM   3860 N NE  . ARG B 1 95  ? 127.987 147.777 123.083 1.00 64.04  ? 95  ARG B NE  1 
ATOM   3861 C CZ  . ARG B 1 95  ? 129.246 147.802 122.676 1.00 68.12  ? 95  ARG B CZ  1 
ATOM   3862 N NH1 . ARG B 1 95  ? 130.247 147.579 123.509 1.00 71.85  ? 95  ARG B NH1 1 
ATOM   3863 N NH2 . ARG B 1 95  ? 129.509 148.061 121.399 1.00 69.85  ? 95  ARG B NH2 1 
ATOM   3864 N N   . PRO B 1 96  ? 128.481 145.380 129.158 1.00 60.70  ? 96  PRO B N   1 
ATOM   3865 C CA  . PRO B 1 96  ? 129.790 145.777 128.625 1.00 63.82  ? 96  PRO B CA  1 
ATOM   3866 C C   . PRO B 1 96  ? 130.668 144.584 128.283 1.00 71.65  ? 96  PRO B C   1 
ATOM   3867 O O   . PRO B 1 96  ? 131.652 144.705 127.561 1.00 75.07  ? 96  PRO B O   1 
ATOM   3868 C CB  . PRO B 1 96  ? 130.383 146.592 129.772 1.00 59.82  ? 96  PRO B CB  1 
ATOM   3869 C CG  . PRO B 1 96  ? 129.802 145.964 130.991 1.00 60.78  ? 96  PRO B CG  1 
ATOM   3870 C CD  . PRO B 1 96  ? 128.395 145.622 130.606 1.00 58.81  ? 96  PRO B CD  1 
ATOM   3871 N N   . HIS B 1 97  ? 130.319 143.409 128.803 1.00 64.40  ? 97  HIS B N   1 
ATOM   3872 C CA  . HIS B 1 97  ? 131.049 142.185 128.531 1.00 57.76  ? 97  HIS B CA  1 
ATOM   3873 C C   . HIS B 1 97  ? 130.153 141.038 128.947 1.00 59.96  ? 97  HIS B C   1 
ATOM   3874 O O   . HIS B 1 97  ? 129.480 141.148 129.979 1.00 70.37  ? 97  HIS B O   1 
ATOM   3875 C CB  . HIS B 1 97  ? 132.373 142.137 129.296 1.00 61.74  ? 97  HIS B CB  1 
ATOM   3876 C CG  . HIS B 1 97  ? 133.359 141.161 128.739 1.00 62.41  ? 97  HIS B CG  1 
ATOM   3877 N ND1 . HIS B 1 97  ? 133.807 140.070 129.448 1.00 68.64  ? 97  HIS B ND1 1 
ATOM   3878 C CD2 . HIS B 1 97  ? 133.985 141.113 127.541 1.00 65.80  ? 97  HIS B CD2 1 
ATOM   3879 C CE1 . HIS B 1 97  ? 134.664 139.389 128.710 1.00 68.54  ? 97  HIS B CE1 1 
ATOM   3880 N NE2 . HIS B 1 97  ? 134.789 140.001 127.548 1.00 63.50  ? 97  HIS B NE2 1 
ATOM   3881 N N   . PRO B 1 98  ? 130.104 139.943 128.191 1.00 50.98  ? 98  PRO B N   1 
ATOM   3882 C CA  . PRO B 1 98  ? 129.241 138.824 128.589 1.00 55.29  ? 98  PRO B CA  1 
ATOM   3883 C C   . PRO B 1 98  ? 129.629 138.207 129.915 1.00 61.43  ? 98  PRO B C   1 
ATOM   3884 O O   . PRO B 1 98  ? 128.793 137.541 130.534 1.00 66.18  ? 98  PRO B O   1 
ATOM   3885 C CB  . PRO B 1 98  ? 129.408 137.826 127.437 1.00 59.07  ? 98  PRO B CB  1 
ATOM   3886 C CG  . PRO B 1 98  ? 129.910 138.632 126.303 1.00 59.23  ? 98  PRO B CG  1 
ATOM   3887 C CD  . PRO B 1 98  ? 130.764 139.694 126.904 1.00 59.49  ? 98  PRO B CD  1 
ATOM   3888 N N   . ALA B 1 99  ? 130.868 138.397 130.369 1.00 56.50  ? 99  ALA B N   1 
ATOM   3889 C CA  . ALA B 1 99  ? 131.277 137.838 131.652 1.00 51.09  ? 99  ALA B CA  1 
ATOM   3890 C C   . ALA B 1 99  ? 130.478 138.438 132.797 1.00 54.64  ? 99  ALA B C   1 
ATOM   3891 O O   . ALA B 1 99  ? 130.114 137.732 133.742 1.00 64.55  ? 99  ALA B O   1 
ATOM   3892 C CB  . ALA B 1 99  ? 132.770 138.059 131.870 1.00 53.95  ? 99  ALA B CB  1 
ATOM   3893 N N   . LEU B 1 100 ? 130.195 139.740 132.732 1.00 49.21  ? 100 LEU B N   1 
ATOM   3894 C CA  . LEU B 1 100 ? 129.444 140.385 133.804 1.00 49.50  ? 100 LEU B CA  1 
ATOM   3895 C C   . LEU B 1 100 ? 128.065 139.763 133.963 1.00 55.04  ? 100 LEU B C   1 
ATOM   3896 O O   . LEU B 1 100 ? 127.616 139.511 135.085 1.00 66.61  ? 100 LEU B O   1 
ATOM   3897 C CB  . LEU B 1 100 ? 129.322 141.882 133.532 1.00 45.48  ? 100 LEU B CB  1 
ATOM   3898 C CG  . LEU B 1 100 ? 128.201 142.591 134.289 1.00 50.68  ? 100 LEU B CG  1 
ATOM   3899 C CD1 . LEU B 1 100 ? 128.469 142.586 135.781 1.00 60.51  ? 100 LEU B CD1 1 
ATOM   3900 C CD2 . LEU B 1 100 ? 128.019 144.003 133.790 1.00 54.90  ? 100 LEU B CD2 1 
ATOM   3901 N N   . TRP B 1 101 ? 127.380 139.501 132.854 1.00 49.84  ? 101 TRP B N   1 
ATOM   3902 C CA  . TRP B 1 101 ? 126.055 138.907 132.921 1.00 46.78  ? 101 TRP B CA  1 
ATOM   3903 C C   . TRP B 1 101 ? 126.088 137.426 133.257 1.00 49.58  ? 101 TRP B C   1 
ATOM   3904 O O   . TRP B 1 101 ? 125.040 136.859 133.579 1.00 57.20  ? 101 TRP B O   1 
ATOM   3905 C CB  . TRP B 1 101 ? 125.317 139.138 131.606 1.00 47.72  ? 101 TRP B CB  1 
ATOM   3906 C CG  . TRP B 1 101 ? 125.016 140.578 131.387 1.00 56.89  ? 101 TRP B CG  1 
ATOM   3907 C CD1 . TRP B 1 101 ? 125.632 141.419 130.516 1.00 52.39  ? 101 TRP B CD1 1 
ATOM   3908 C CD2 . TRP B 1 101 ? 124.037 141.358 132.075 1.00 57.99  ? 101 TRP B CD2 1 
ATOM   3909 N NE1 . TRP B 1 101 ? 125.092 142.674 130.610 1.00 47.57  ? 101 TRP B NE1 1 
ATOM   3910 C CE2 . TRP B 1 101 ? 124.108 142.661 131.562 1.00 52.44  ? 101 TRP B CE2 1 
ATOM   3911 C CE3 . TRP B 1 101 ? 123.102 141.078 133.072 1.00 53.07  ? 101 TRP B CE3 1 
ATOM   3912 C CZ2 . TRP B 1 101 ? 123.283 143.681 132.010 1.00 53.96  ? 101 TRP B CZ2 1 
ATOM   3913 C CZ3 . TRP B 1 101 ? 122.285 142.093 133.515 1.00 54.09  ? 101 TRP B CZ3 1 
ATOM   3914 C CH2 . TRP B 1 101 ? 122.380 143.378 132.986 1.00 53.04  ? 101 TRP B CH2 1 
ATOM   3915 N N   . ARG B 1 102 ? 127.252 136.784 133.179 1.00 52.25  ? 102 ARG B N   1 
ATOM   3916 C CA  . ARG B 1 102 ? 127.397 135.452 133.749 1.00 43.52  ? 102 ARG B CA  1 
ATOM   3917 C C   . ARG B 1 102 ? 127.532 135.517 135.264 1.00 43.01  ? 102 ARG B C   1 
ATOM   3918 O O   . ARG B 1 102 ? 126.984 134.671 135.975 1.00 54.75  ? 102 ARG B O   1 
ATOM   3919 C CB  . ARG B 1 102 ? 128.604 134.747 133.140 1.00 48.56  ? 102 ARG B CB  1 
ATOM   3920 C CG  . ARG B 1 102 ? 128.451 134.425 131.677 1.00 46.39  ? 102 ARG B CG  1 
ATOM   3921 C CD  . ARG B 1 102 ? 129.766 133.984 131.086 1.00 47.87  ? 102 ARG B CD  1 
ATOM   3922 N NE  . ARG B 1 102 ? 129.733 133.985 129.631 1.00 45.10  ? 102 ARG B NE  1 
ATOM   3923 C CZ  . ARG B 1 102 ? 130.810 134.043 128.863 1.00 54.76  ? 102 ARG B CZ  1 
ATOM   3924 N NH1 . ARG B 1 102 ? 132.024 134.107 129.381 1.00 61.06  ? 102 ARG B NH1 1 
ATOM   3925 N NH2 . ARG B 1 102 ? 130.664 134.044 127.543 1.00 51.73  ? 102 ARG B NH2 1 
ATOM   3926 N N   . MET B 1 103 ? 128.262 136.512 135.772 1.00 42.74  ? 103 MET B N   1 
ATOM   3927 C CA  . MET B 1 103 ? 128.350 136.708 137.214 1.00 44.20  ? 103 MET B CA  1 
ATOM   3928 C C   . MET B 1 103 ? 126.997 137.076 137.803 1.00 48.29  ? 103 MET B C   1 
ATOM   3929 O O   . MET B 1 103 ? 126.651 136.632 138.902 1.00 56.82  ? 103 MET B O   1 
ATOM   3930 C CB  . MET B 1 103 ? 129.374 137.789 137.540 1.00 37.34  ? 103 MET B CB  1 
ATOM   3931 C CG  . MET B 1 103 ? 130.792 137.457 137.154 1.00 41.33  ? 103 MET B CG  1 
ATOM   3932 S SD  . MET B 1 103 ? 131.820 138.930 137.164 1.00 63.74  ? 103 MET B SD  1 
ATOM   3933 C CE  . MET B 1 103 ? 133.446 138.197 137.190 1.00 53.30  ? 103 MET B CE  1 
ATOM   3934 N N   . VAL B 1 104 ? 126.227 137.900 137.094 1.00 45.62  ? 104 VAL B N   1 
ATOM   3935 C CA  . VAL B 1 104 ? 124.893 138.261 137.561 1.00 36.48  ? 104 VAL B CA  1 
ATOM   3936 C C   . VAL B 1 104 ? 123.998 137.030 137.615 1.00 42.84  ? 104 VAL B C   1 
ATOM   3937 O O   . VAL B 1 104 ? 123.184 136.877 138.531 1.00 53.82  ? 104 VAL B O   1 
ATOM   3938 C CB  . VAL B 1 104 ? 124.305 139.367 136.668 1.00 40.57  ? 104 VAL B CB  1 
ATOM   3939 C CG1 . VAL B 1 104 ? 122.846 139.553 136.947 1.00 38.76  ? 104 VAL B CG1 1 
ATOM   3940 C CG2 . VAL B 1 104 ? 125.044 140.666 136.897 1.00 45.41  ? 104 VAL B CG2 1 
ATOM   3941 N N   . PHE B 1 105 ? 124.130 136.134 136.635 1.00 44.88  ? 105 PHE B N   1 
ATOM   3942 C CA  . PHE B 1 105 ? 123.440 134.850 136.714 1.00 34.47  ? 105 PHE B CA  1 
ATOM   3943 C C   . PHE B 1 105 ? 123.978 134.006 137.859 1.00 42.52  ? 105 PHE B C   1 
ATOM   3944 O O   . PHE B 1 105 ? 123.214 133.324 138.550 1.00 42.49  ? 105 PHE B O   1 
ATOM   3945 C CB  . PHE B 1 105 ? 123.575 134.088 135.399 1.00 34.83  ? 105 PHE B CB  1 
ATOM   3946 C CG  . PHE B 1 105 ? 122.780 132.821 135.355 1.00 39.27  ? 105 PHE B CG  1 
ATOM   3947 C CD1 . PHE B 1 105 ? 121.546 132.744 135.956 1.00 52.48  ? 105 PHE B CD1 1 
ATOM   3948 C CD2 . PHE B 1 105 ? 123.281 131.697 134.745 1.00 44.45  ? 105 PHE B CD2 1 
ATOM   3949 C CE1 . PHE B 1 105 ? 120.820 131.579 135.924 1.00 50.06  ? 105 PHE B CE1 1 
ATOM   3950 C CE2 . PHE B 1 105 ? 122.556 130.531 134.716 1.00 40.09  ? 105 PHE B CE2 1 
ATOM   3951 C CZ  . PHE B 1 105 ? 121.327 130.474 135.306 1.00 32.68  ? 105 PHE B CZ  1 
ATOM   3952 N N   . GLY B 1 106 ? 125.294 134.028 138.069 1.00 51.37  ? 106 GLY B N   1 
ATOM   3953 C CA  . GLY B 1 106 ? 125.873 133.257 139.153 1.00 36.96  ? 106 GLY B CA  1 
ATOM   3954 C C   . GLY B 1 106 ? 125.368 133.681 140.515 1.00 45.89  ? 106 GLY B C   1 
ATOM   3955 O O   . GLY B 1 106 ? 125.371 132.887 141.455 1.00 62.31  ? 106 GLY B O   1 
ATOM   3956 N N   . LEU B 1 107 ? 124.939 134.935 140.645 1.00 43.84  ? 107 LEU B N   1 
ATOM   3957 C CA  . LEU B 1 107 ? 124.313 135.374 141.885 1.00 36.73  ? 107 LEU B CA  1 
ATOM   3958 C C   . LEU B 1 107 ? 122.885 134.857 141.995 1.00 46.90  ? 107 LEU B C   1 
ATOM   3959 O O   . LEU B 1 107 ? 122.413 134.558 143.096 1.00 64.76  ? 107 LEU B O   1 
ATOM   3960 C CB  . LEU B 1 107 ? 124.339 136.897 141.975 1.00 41.67  ? 107 LEU B CB  1 
ATOM   3961 C CG  . LEU B 1 107 ? 125.703 137.559 142.144 1.00 45.66  ? 107 LEU B CG  1 
ATOM   3962 C CD1 . LEU B 1 107 ? 125.545 139.060 142.242 1.00 46.60  ? 107 LEU B CD1 1 
ATOM   3963 C CD2 . LEU B 1 107 ? 126.408 137.016 143.366 1.00 42.85  ? 107 LEU B CD2 1 
ATOM   3964 N N   . SER B 1 108 ? 122.177 134.751 140.868 1.00 43.10  ? 108 SER B N   1 
ATOM   3965 C CA  . SER B 1 108 ? 120.810 134.240 140.897 1.00 38.68  ? 108 SER B CA  1 
ATOM   3966 C C   . SER B 1 108 ? 120.770 132.805 141.392 1.00 56.64  ? 108 SER B C   1 
ATOM   3967 O O   . SER B 1 108 ? 119.907 132.441 142.197 1.00 65.40  ? 108 SER B O   1 
ATOM   3968 C CB  . SER B 1 108 ? 120.186 134.317 139.511 1.00 35.67  ? 108 SER B CB  1 
ATOM   3969 O OG  . SER B 1 108 ? 120.592 135.482 138.837 1.00 55.89  ? 108 SER B OG  1 
ATOM   3970 N N   . VAL B 1 109 ? 121.689 131.969 140.912 1.00 42.33  ? 109 VAL B N   1 
ATOM   3971 C CA  . VAL B 1 109 ? 121.734 130.587 141.369 1.00 32.61  ? 109 VAL B CA  1 
ATOM   3972 C C   . VAL B 1 109 ? 122.118 130.532 142.840 1.00 47.08  ? 109 VAL B C   1 
ATOM   3973 O O   . VAL B 1 109 ? 121.582 129.723 143.604 1.00 60.37  ? 109 VAL B O   1 
ATOM   3974 C CB  . VAL B 1 109 ? 122.697 129.769 140.495 1.00 33.05  ? 109 VAL B CB  1 
ATOM   3975 C CG1 . VAL B 1 109 ? 122.819 128.356 141.022 1.00 41.16  ? 109 VAL B CG1 1 
ATOM   3976 C CG2 . VAL B 1 109 ? 122.223 129.766 139.062 1.00 44.83  ? 109 VAL B CG2 1 
ATOM   3977 N N   . LEU B 1 110 ? 123.048 131.388 143.264 1.00 45.48  ? 110 LEU B N   1 
ATOM   3978 C CA  . LEU B 1 110 ? 123.379 131.468 144.682 1.00 34.96  ? 110 LEU B CA  1 
ATOM   3979 C C   . LEU B 1 110 ? 122.173 131.896 145.501 1.00 39.85  ? 110 LEU B C   1 
ATOM   3980 O O   . LEU B 1 110 ? 121.911 131.341 146.572 1.00 53.28  ? 110 LEU B O   1 
ATOM   3981 C CB  . LEU B 1 110 ? 124.532 132.441 144.903 1.00 36.34  ? 110 LEU B CB  1 
ATOM   3982 C CG  . LEU B 1 110 ? 125.957 131.917 144.788 1.00 42.52  ? 110 LEU B CG  1 
ATOM   3983 C CD1 . LEU B 1 110 ? 126.928 133.008 145.168 1.00 48.51  ? 110 LEU B CD1 1 
ATOM   3984 C CD2 . LEU B 1 110 ? 126.147 130.713 145.668 1.00 47.64  ? 110 LEU B CD2 1 
ATOM   3985 N N   . TYR B 1 111 ? 121.427 132.888 145.016 1.00 39.96  ? 111 TYR B N   1 
ATOM   3986 C CA  . TYR B 1 111 ? 120.271 133.369 145.763 1.00 40.85  ? 111 TYR B CA  1 
ATOM   3987 C C   . TYR B 1 111 ? 119.133 132.361 145.737 1.00 44.60  ? 111 TYR B C   1 
ATOM   3988 O O   . TYR B 1 111 ? 118.465 132.150 146.754 1.00 57.46  ? 111 TYR B O   1 
ATOM   3989 C CB  . TYR B 1 111 ? 119.802 134.709 145.210 1.00 35.36  ? 111 TYR B CB  1 
ATOM   3990 C CG  . TYR B 1 111 ? 118.734 135.348 146.054 1.00 42.98  ? 111 TYR B CG  1 
ATOM   3991 C CD1 . TYR B 1 111 ? 118.865 135.417 147.428 1.00 56.74  ? 111 TYR B CD1 1 
ATOM   3992 C CD2 . TYR B 1 111 ? 117.596 135.882 145.480 1.00 50.41  ? 111 TYR B CD2 1 
ATOM   3993 C CE1 . TYR B 1 111 ? 117.895 135.999 148.206 1.00 58.08  ? 111 TYR B CE1 1 
ATOM   3994 C CE2 . TYR B 1 111 ? 116.621 136.465 146.252 1.00 47.96  ? 111 TYR B CE2 1 
ATOM   3995 C CZ  . TYR B 1 111 ? 116.777 136.519 147.613 1.00 52.68  ? 111 TYR B CZ  1 
ATOM   3996 O OH  . TYR B 1 111 ? 115.809 137.101 148.389 1.00 59.12  ? 111 TYR B OH  1 
ATOM   3997 N N   . PHE B 1 112 ? 118.887 131.736 144.585 1.00 37.91  ? 112 PHE B N   1 
ATOM   3998 C CA  . PHE B 1 112 ? 117.802 130.765 144.495 1.00 35.73  ? 112 PHE B CA  1 
ATOM   3999 C C   . PHE B 1 112 ? 118.042 129.593 145.435 1.00 51.02  ? 112 PHE B C   1 
ATOM   4000 O O   . PHE B 1 112 ? 117.122 129.150 146.128 1.00 55.73  ? 112 PHE B O   1 
ATOM   4001 C CB  . PHE B 1 112 ? 117.646 130.299 143.044 1.00 31.41  ? 112 PHE B CB  1 
ATOM   4002 C CG  . PHE B 1 112 ? 117.202 128.869 142.890 1.00 38.67  ? 112 PHE B CG  1 
ATOM   4003 C CD1 . PHE B 1 112 ? 115.986 128.437 143.382 1.00 45.89  ? 112 PHE B CD1 1 
ATOM   4004 C CD2 . PHE B 1 112 ? 117.996 127.964 142.216 1.00 42.68  ? 112 PHE B CD2 1 
ATOM   4005 C CE1 . PHE B 1 112 ? 115.593 127.126 143.230 1.00 43.20  ? 112 PHE B CE1 1 
ATOM   4006 C CE2 . PHE B 1 112 ? 117.599 126.657 142.059 1.00 47.00  ? 112 PHE B CE2 1 
ATOM   4007 C CZ  . PHE B 1 112 ? 116.397 126.241 142.564 1.00 46.18  ? 112 PHE B CZ  1 
ATOM   4008 N N   . LEU B 1 113 ? 119.276 129.089 145.488 1.00 54.73  ? 113 LEU B N   1 
ATOM   4009 C CA  . LEU B 1 113 ? 119.585 127.988 146.393 1.00 40.37  ? 113 LEU B CA  1 
ATOM   4010 C C   . LEU B 1 113 ? 119.498 128.417 147.849 1.00 46.53  ? 113 LEU B C   1 
ATOM   4011 O O   . LEU B 1 113 ? 119.139 127.609 148.710 1.00 62.53  ? 113 LEU B O   1 
ATOM   4012 C CB  . LEU B 1 113 ? 120.973 127.435 146.094 1.00 31.72  ? 113 LEU B CB  1 
ATOM   4013 C CG  . LEU B 1 113 ? 121.164 126.795 144.727 1.00 34.12  ? 113 LEU B CG  1 
ATOM   4014 C CD1 . LEU B 1 113 ? 122.607 126.415 144.559 1.00 46.22  ? 113 LEU B CD1 1 
ATOM   4015 C CD2 . LEU B 1 113 ? 120.270 125.592 144.577 1.00 40.40  ? 113 LEU B CD2 1 
ATOM   4016 N N   . PHE B 1 114 ? 119.835 129.671 148.143 1.00 38.38  ? 114 PHE B N   1 
ATOM   4017 C CA  . PHE B 1 114 ? 119.712 130.172 149.506 1.00 39.12  ? 114 PHE B CA  1 
ATOM   4018 C C   . PHE B 1 114 ? 118.264 130.132 149.973 1.00 48.48  ? 114 PHE B C   1 
ATOM   4019 O O   . PHE B 1 114 ? 117.983 129.768 151.119 1.00 53.17  ? 114 PHE B O   1 
ATOM   4020 C CB  . PHE B 1 114 ? 120.268 131.591 149.580 1.00 41.52  ? 114 PHE B CB  1 
ATOM   4021 C CG  . PHE B 1 114 ? 120.045 132.265 150.894 1.00 44.01  ? 114 PHE B CG  1 
ATOM   4022 C CD1 . PHE B 1 114 ? 120.668 131.807 152.036 1.00 49.08  ? 114 PHE B CD1 1 
ATOM   4023 C CD2 . PHE B 1 114 ? 119.216 133.364 150.985 1.00 45.29  ? 114 PHE B CD2 1 
ATOM   4024 C CE1 . PHE B 1 114 ? 120.466 132.431 153.243 1.00 48.28  ? 114 PHE B CE1 1 
ATOM   4025 C CE2 . PHE B 1 114 ? 119.010 133.991 152.189 1.00 52.18  ? 114 PHE B CE2 1 
ATOM   4026 C CZ  . PHE B 1 114 ? 119.637 133.524 153.319 1.00 52.64  ? 114 PHE B CZ  1 
ATOM   4027 N N   . LEU B 1 115 ? 117.329 130.499 149.095 1.00 54.33  ? 115 LEU B N   1 
ATOM   4028 C CA  . LEU B 1 115 ? 115.914 130.439 149.442 1.00 49.04  ? 115 LEU B CA  1 
ATOM   4029 C C   . LEU B 1 115 ? 115.430 129.006 149.594 1.00 50.77  ? 115 LEU B C   1 
ATOM   4030 O O   . LEU B 1 115 ? 114.485 128.751 150.345 1.00 61.16  ? 115 LEU B O   1 
ATOM   4031 C CB  . LEU B 1 115 ? 115.084 131.157 148.384 1.00 45.25  ? 115 LEU B CB  1 
ATOM   4032 C CG  . LEU B 1 115 ? 115.340 132.652 148.252 1.00 50.43  ? 115 LEU B CG  1 
ATOM   4033 C CD1 . LEU B 1 115 ? 114.533 133.210 147.111 1.00 51.19  ? 115 LEU B CD1 1 
ATOM   4034 C CD2 . LEU B 1 115 ? 114.994 133.351 149.545 1.00 53.45  ? 115 LEU B CD2 1 
ATOM   4035 N N   . VAL B 1 116 ? 116.039 128.063 148.874 1.00 36.58  ? 116 VAL B N   1 
ATOM   4036 C CA  . VAL B 1 116 ? 115.694 126.658 149.058 1.00 40.88  ? 116 VAL B CA  1 
ATOM   4037 C C   . VAL B 1 116 ? 116.063 126.208 150.464 1.00 47.98  ? 116 VAL B C   1 
ATOM   4038 O O   . VAL B 1 116 ? 115.334 125.438 151.100 1.00 49.19  ? 116 VAL B O   1 
ATOM   4039 C CB  . VAL B 1 116 ? 116.382 125.794 147.987 1.00 40.51  ? 116 VAL B CB  1 
ATOM   4040 C CG1 . VAL B 1 116 ? 116.146 124.334 148.260 1.00 38.92  ? 116 VAL B CG1 1 
ATOM   4041 C CG2 . VAL B 1 116 ? 115.869 126.151 146.619 1.00 44.09  ? 116 VAL B CG2 1 
ATOM   4042 N N   . PHE B 1 117 ? 117.201 126.682 150.969 1.00 51.76  ? 117 PHE B N   1 
ATOM   4043 C CA  . PHE B 1 117 ? 117.630 126.327 152.316 1.00 36.24  ? 117 PHE B CA  1 
ATOM   4044 C C   . PHE B 1 117 ? 116.676 126.887 153.362 1.00 45.16  ? 117 PHE B C   1 
ATOM   4045 O O   . PHE B 1 117 ? 116.252 126.173 154.276 1.00 61.24  ? 117 PHE B O   1 
ATOM   4046 C CB  . PHE B 1 117 ? 119.048 126.837 152.552 1.00 34.59  ? 117 PHE B CB  1 
ATOM   4047 C CG  . PHE B 1 117 ? 119.709 126.251 153.756 1.00 47.46  ? 117 PHE B CG  1 
ATOM   4048 C CD1 . PHE B 1 117 ? 120.073 124.922 153.779 1.00 49.29  ? 117 PHE B CD1 1 
ATOM   4049 C CD2 . PHE B 1 117 ? 119.977 127.031 154.860 1.00 55.72  ? 117 PHE B CD2 1 
ATOM   4050 C CE1 . PHE B 1 117 ? 120.683 124.381 154.882 1.00 54.92  ? 117 PHE B CE1 1 
ATOM   4051 C CE2 . PHE B 1 117 ? 120.589 126.494 155.965 1.00 55.27  ? 117 PHE B CE2 1 
ATOM   4052 C CZ  . PHE B 1 117 ? 120.941 125.167 155.976 1.00 57.53  ? 117 PHE B CZ  1 
ATOM   4053 N N   . LEU B 1 118 ? 116.313 128.164 153.235 1.00 50.82  ? 118 LEU B N   1 
ATOM   4054 C CA  . LEU B 1 118 ? 115.455 128.805 154.225 1.00 49.59  ? 118 LEU B CA  1 
ATOM   4055 C C   . LEU B 1 118 ? 114.096 128.139 154.346 1.00 55.86  ? 118 LEU B C   1 
ATOM   4056 O O   . LEU B 1 118 ? 113.458 128.251 155.396 1.00 58.79  ? 118 LEU B O   1 
ATOM   4057 C CB  . LEU B 1 118 ? 115.261 130.278 153.887 1.00 44.76  ? 118 LEU B CB  1 
ATOM   4058 C CG  . LEU B 1 118 ? 116.107 131.283 154.655 1.00 51.99  ? 118 LEU B CG  1 
ATOM   4059 C CD1 . LEU B 1 118 ? 117.565 130.914 154.578 1.00 57.32  ? 118 LEU B CD1 1 
ATOM   4060 C CD2 . LEU B 1 118 ? 115.876 132.669 154.092 1.00 56.51  ? 118 LEU B CD2 1 
ATOM   4061 N N   . LEU B 1 119 ? 113.632 127.456 153.303 1.00 54.69  ? 119 LEU B N   1 
ATOM   4062 C CA  . LEU B 1 119 ? 112.316 126.840 153.362 1.00 52.75  ? 119 LEU B CA  1 
ATOM   4063 C C   . LEU B 1 119 ? 112.287 125.615 154.260 1.00 56.10  ? 119 LEU B C   1 
ATOM   4064 O O   . LEU B 1 119 ? 111.202 125.093 154.533 1.00 56.12  ? 119 LEU B O   1 
ATOM   4065 C CB  . LEU B 1 119 ? 111.850 126.483 151.953 1.00 39.08  ? 119 LEU B CB  1 
ATOM   4066 C CG  . LEU B 1 119 ? 111.123 127.655 151.302 1.00 41.91  ? 119 LEU B CG  1 
ATOM   4067 C CD1 . LEU B 1 119 ? 111.013 127.491 149.810 1.00 51.07  ? 119 LEU B CD1 1 
ATOM   4068 C CD2 . LEU B 1 119 ? 109.760 127.820 151.920 1.00 52.04  ? 119 LEU B CD2 1 
ATOM   4069 N N   . PHE B 1 120 ? 113.443 125.149 154.724 1.00 54.40  ? 120 PHE B N   1 
ATOM   4070 C CA  . PHE B 1 120 ? 113.510 124.045 155.669 1.00 51.51  ? 120 PHE B CA  1 
ATOM   4071 C C   . PHE B 1 120 ? 113.826 124.496 157.085 1.00 56.45  ? 120 PHE B C   1 
ATOM   4072 O O   . PHE B 1 120 ? 113.441 123.817 158.039 1.00 69.48  ? 120 PHE B O   1 
ATOM   4073 C CB  . PHE B 1 120 ? 114.558 123.026 155.215 1.00 46.93  ? 120 PHE B CB  1 
ATOM   4074 C CG  . PHE B 1 120 ? 114.160 122.262 153.992 1.00 43.12  ? 120 PHE B CG  1 
ATOM   4075 C CD1 . PHE B 1 120 ? 114.309 122.815 152.739 1.00 48.06  ? 120 PHE B CD1 1 
ATOM   4076 C CD2 . PHE B 1 120 ? 113.625 120.996 154.096 1.00 54.68  ? 120 PHE B CD2 1 
ATOM   4077 C CE1 . PHE B 1 120 ? 113.940 122.121 151.618 1.00 52.80  ? 120 PHE B CE1 1 
ATOM   4078 C CE2 . PHE B 1 120 ? 113.254 120.298 152.975 1.00 57.91  ? 120 PHE B CE2 1 
ATOM   4079 C CZ  . PHE B 1 120 ? 113.413 120.861 151.736 1.00 55.60  ? 120 PHE B CZ  1 
ATOM   4080 N N   . LEU B 1 121 ? 114.512 125.621 157.243 1.00 44.87  ? 121 LEU B N   1 
ATOM   4081 C CA  . LEU B 1 121 ? 114.781 126.161 158.565 1.00 50.57  ? 121 LEU B CA  1 
ATOM   4082 C C   . LEU B 1 121 ? 113.499 126.701 159.187 1.00 61.16  ? 121 LEU B C   1 
ATOM   4083 O O   . LEU B 1 121 ? 112.609 127.195 158.493 1.00 66.28  ? 121 LEU B O   1 
ATOM   4084 C CB  . LEU B 1 121 ? 115.826 127.270 158.482 1.00 49.66  ? 121 LEU B CB  1 
ATOM   4085 C CG  . LEU B 1 121 ? 117.308 126.904 158.551 1.00 52.75  ? 121 LEU B CG  1 
ATOM   4086 C CD1 . LEU B 1 121 ? 117.648 125.756 157.635 1.00 56.93  ? 121 LEU B CD1 1 
ATOM   4087 C CD2 . LEU B 1 121 ? 118.152 128.109 158.210 1.00 60.11  ? 121 LEU B CD2 1 
ATOM   4088 N N   . ASN B 1 122 ? 113.405 126.598 160.507 1.00 64.04  ? 122 ASN B N   1 
ATOM   4089 C CA  . ASN B 1 122 ? 112.273 127.164 161.224 1.00 59.61  ? 122 ASN B CA  1 
ATOM   4090 C C   . ASN B 1 122 ? 112.540 128.628 161.562 1.00 66.63  ? 122 ASN B C   1 
ATOM   4091 O O   . ASN B 1 122 ? 113.652 129.135 161.417 1.00 72.24  ? 122 ASN B O   1 
ATOM   4092 C CB  . ASN B 1 122 ? 111.969 126.354 162.483 1.00 63.17  ? 122 ASN B CB  1 
ATOM   4093 C CG  . ASN B 1 122 ? 113.173 126.192 163.380 1.00 69.04  ? 122 ASN B CG  1 
ATOM   4094 O OD1 . ASN B 1 122 ? 114.310 126.282 162.928 1.00 68.80  ? 122 ASN B OD1 1 
ATOM   4095 N ND2 . ASN B 1 122 ? 112.929 125.942 164.659 1.00 67.84  ? 122 ASN B ND2 1 
ATOM   4096 N N   . PHE B 1 123 ? 111.490 129.313 162.021 1.00 68.27  ? 123 PHE B N   1 
ATOM   4097 C CA  . PHE B 1 123 ? 111.565 130.763 162.179 1.00 73.66  ? 123 PHE B CA  1 
ATOM   4098 C C   . PHE B 1 123 ? 112.622 131.177 163.191 1.00 72.21  ? 123 PHE B C   1 
ATOM   4099 O O   . PHE B 1 123 ? 113.190 132.268 163.079 1.00 74.82  ? 123 PHE B O   1 
ATOM   4100 C CB  . PHE B 1 123 ? 110.204 131.320 162.586 1.00 74.99  ? 123 PHE B CB  1 
ATOM   4101 C CG  . PHE B 1 123 ? 110.113 132.813 162.497 1.00 78.20  ? 123 PHE B CG  1 
ATOM   4102 C CD1 . PHE B 1 123 ? 110.775 133.502 161.499 1.00 74.81  ? 123 PHE B CD1 1 
ATOM   4103 C CD2 . PHE B 1 123 ? 109.364 133.530 163.411 1.00 76.29  ? 123 PHE B CD2 1 
ATOM   4104 C CE1 . PHE B 1 123 ? 110.693 134.874 161.415 1.00 69.49  ? 123 PHE B CE1 1 
ATOM   4105 C CE2 . PHE B 1 123 ? 109.279 134.903 163.331 1.00 75.32  ? 123 PHE B CE2 1 
ATOM   4106 C CZ  . PHE B 1 123 ? 109.944 135.574 162.333 1.00 73.11  ? 123 PHE B CZ  1 
ATOM   4107 N N   . GLU B 1 124 ? 112.898 130.335 164.187 1.00 75.21  ? 124 GLU B N   1 
ATOM   4108 C CA  . GLU B 1 124 ? 113.940 130.666 165.152 1.00 73.18  ? 124 GLU B CA  1 
ATOM   4109 C C   . GLU B 1 124 ? 115.324 130.594 164.524 1.00 72.16  ? 124 GLU B C   1 
ATOM   4110 O O   . GLU B 1 124 ? 116.209 131.373 164.891 1.00 78.36  ? 124 GLU B O   1 
ATOM   4111 C CB  . GLU B 1 124 ? 113.867 129.743 166.370 1.00 73.91  ? 124 GLU B CB  1 
ATOM   4112 C CG  . GLU B 1 124 ? 112.651 129.933 167.281 1.00 79.55  ? 124 GLU B CG  1 
ATOM   4113 C CD  . GLU B 1 124 ? 111.318 129.810 166.562 1.00 83.15  ? 124 GLU B CD  1 
ATOM   4114 O OE1 . GLU B 1 124 ? 111.124 128.820 165.827 1.00 81.54  ? 124 GLU B OE1 1 
ATOM   4115 O OE2 . GLU B 1 124 ? 110.465 130.705 166.732 1.00 81.79  ? 124 GLU B OE2 1 
ATOM   4116 N N   . GLN B 1 125 ? 115.533 129.667 163.590 1.00 68.34  ? 125 GLN B N   1 
ATOM   4117 C CA  . GLN B 1 125 ? 116.837 129.535 162.952 1.00 64.87  ? 125 GLN B CA  1 
ATOM   4118 C C   . GLN B 1 125 ? 117.072 130.626 161.919 1.00 65.08  ? 125 GLN B C   1 
ATOM   4119 O O   . GLN B 1 125 ? 118.196 131.116 161.779 1.00 71.14  ? 125 GLN B O   1 
ATOM   4120 C CB  . GLN B 1 125 ? 116.968 128.159 162.306 1.00 65.97  ? 125 GLN B CB  1 
ATOM   4121 C CG  . GLN B 1 125 ? 117.358 127.062 163.266 1.00 69.84  ? 125 GLN B CG  1 
ATOM   4122 C CD  . GLN B 1 125 ? 117.410 125.711 162.597 1.00 73.28  ? 125 GLN B CD  1 
ATOM   4123 O OE1 . GLN B 1 125 ? 118.476 125.120 162.453 1.00 74.93  ? 125 GLN B OE1 1 
ATOM   4124 N NE2 . GLN B 1 125 ? 116.254 125.211 162.187 1.00 70.78  ? 125 GLN B NE2 1 
ATOM   4125 N N   . VAL B 1 126 ? 116.030 131.010 161.179 1.00 64.35  ? 126 VAL B N   1 
ATOM   4126 C CA  . VAL B 1 126 ? 116.169 132.099 160.217 1.00 65.09  ? 126 VAL B CA  1 
ATOM   4127 C C   . VAL B 1 126 ? 116.475 133.404 160.937 1.00 67.47  ? 126 VAL B C   1 
ATOM   4128 O O   . VAL B 1 126 ? 117.342 134.176 160.512 1.00 72.72  ? 126 VAL B O   1 
ATOM   4129 C CB  . VAL B 1 126 ? 114.906 132.211 159.347 1.00 58.54  ? 126 VAL B CB  1 
ATOM   4130 C CG1 . VAL B 1 126 ? 114.934 133.488 158.548 1.00 66.05  ? 126 VAL B CG1 1 
ATOM   4131 C CG2 . VAL B 1 126 ? 114.806 131.028 158.421 1.00 56.99  ? 126 VAL B CG2 1 
ATOM   4132 N N   . LYS B 1 127 ? 115.776 133.668 162.042 1.00 67.80  ? 127 LYS B N   1 
ATOM   4133 C CA  . LYS B 1 127 ? 116.088 134.845 162.844 1.00 66.96  ? 127 LYS B CA  1 
ATOM   4134 C C   . LYS B 1 127 ? 117.501 134.765 163.405 1.00 70.08  ? 127 LYS B C   1 
ATOM   4135 O O   . LYS B 1 127 ? 118.243 135.753 163.379 1.00 83.41  ? 127 LYS B O   1 
ATOM   4136 C CB  . LYS B 1 127 ? 115.073 134.994 163.973 1.00 71.05  ? 127 LYS B CB  1 
ATOM   4137 C CG  . LYS B 1 127 ? 113.715 135.495 163.525 1.00 77.18  ? 127 LYS B CG  1 
ATOM   4138 C CD  . LYS B 1 127 ? 113.812 136.901 162.967 1.00 80.12  ? 127 LYS B CD  1 
ATOM   4139 C CE  . LYS B 1 127 ? 112.706 137.794 163.499 1.00 78.52  ? 127 LYS B CE  1 
ATOM   4140 N NZ  . LYS B 1 127 ? 113.125 139.222 163.525 1.00 76.67  ? 127 LYS B NZ  1 
ATOM   4141 N N   . SER B 1 128 ? 117.896 133.594 163.908 1.00 69.51  ? 128 SER B N   1 
ATOM   4142 C CA  . SER B 1 128 ? 119.249 133.429 164.428 1.00 71.08  ? 128 SER B CA  1 
ATOM   4143 C C   . SER B 1 128 ? 120.283 133.618 163.330 1.00 71.53  ? 128 SER B C   1 
ATOM   4144 O O   . SER B 1 128 ? 121.352 134.192 163.563 1.00 74.16  ? 128 SER B O   1 
ATOM   4145 C CB  . SER B 1 128 ? 119.403 132.053 165.074 1.00 73.56  ? 128 SER B CB  1 
ATOM   4146 O OG  . SER B 1 128 ? 118.517 131.901 166.169 1.00 82.36  ? 128 SER B OG  1 
ATOM   4147 N N   . LEU B 1 129 ? 119.990 133.122 162.129 1.00 78.10  ? 129 LEU B N   1 
ATOM   4148 C CA  . LEU B 1 129 ? 120.882 133.340 160.996 1.00 72.98  ? 129 LEU B CA  1 
ATOM   4149 C C   . LEU B 1 129 ? 120.955 134.815 160.627 1.00 72.54  ? 129 LEU B C   1 
ATOM   4150 O O   . LEU B 1 129 ? 122.035 135.331 160.323 1.00 80.23  ? 129 LEU B O   1 
ATOM   4151 C CB  . LEU B 1 129 ? 120.412 132.505 159.805 1.00 71.75  ? 129 LEU B CB  1 
ATOM   4152 C CG  . LEU B 1 129 ? 120.881 132.893 158.408 1.00 72.52  ? 129 LEU B CG  1 
ATOM   4153 C CD1 . LEU B 1 129 ? 122.384 132.848 158.337 1.00 78.47  ? 129 LEU B CD1 1 
ATOM   4154 C CD2 . LEU B 1 129 ? 120.270 131.962 157.377 1.00 73.73  ? 129 LEU B CD2 1 
ATOM   4155 N N   . MET B 1 130 ? 119.817 135.510 160.646 1.00 78.17  ? 130 MET B N   1 
ATOM   4156 C CA  . MET B 1 130 ? 119.809 136.916 160.260 1.00 76.50  ? 130 MET B CA  1 
ATOM   4157 C C   . MET B 1 130 ? 120.580 137.771 161.255 1.00 73.69  ? 130 MET B C   1 
ATOM   4158 O O   . MET B 1 130 ? 121.312 138.682 160.856 1.00 80.53  ? 130 MET B O   1 
ATOM   4159 C CB  . MET B 1 130 ? 118.376 137.415 160.121 1.00 75.72  ? 130 MET B CB  1 
ATOM   4160 C CG  . MET B 1 130 ? 118.259 138.675 159.295 1.00 81.95  ? 130 MET B CG  1 
ATOM   4161 S SD  . MET B 1 130 ? 116.606 139.383 159.286 1.00 102.48 ? 130 MET B SD  1 
ATOM   4162 C CE  . MET B 1 130 ? 115.725 138.206 160.298 1.00 81.80  ? 130 MET B CE  1 
ATOM   4163 N N   . TYR B 1 131 ? 120.428 137.499 162.553 1.00 72.98  ? 131 TYR B N   1 
ATOM   4164 C CA  . TYR B 1 131 ? 121.205 138.232 163.546 1.00 76.23  ? 131 TYR B CA  1 
ATOM   4165 C C   . TYR B 1 131 ? 122.695 137.991 163.368 1.00 79.79  ? 131 TYR B C   1 
ATOM   4166 O O   . TYR B 1 131 ? 123.510 138.857 163.701 1.00 82.85  ? 131 TYR B O   1 
ATOM   4167 C CB  . TYR B 1 131 ? 120.779 137.839 164.959 1.00 75.62  ? 131 TYR B CB  1 
ATOM   4168 C CG  . TYR B 1 131 ? 119.312 138.036 165.245 1.00 78.20  ? 131 TYR B CG  1 
ATOM   4169 C CD1 . TYR B 1 131 ? 118.601 139.069 164.655 1.00 79.45  ? 131 TYR B CD1 1 
ATOM   4170 C CD2 . TYR B 1 131 ? 118.640 137.192 166.115 1.00 81.14  ? 131 TYR B CD2 1 
ATOM   4171 C CE1 . TYR B 1 131 ? 117.259 139.250 164.918 1.00 84.35  ? 131 TYR B CE1 1 
ATOM   4172 C CE2 . TYR B 1 131 ? 117.300 137.364 166.383 1.00 83.19  ? 131 TYR B CE2 1 
ATOM   4173 C CZ  . TYR B 1 131 ? 116.614 138.394 165.783 1.00 85.24  ? 131 TYR B CZ  1 
ATOM   4174 O OH  . TYR B 1 131 ? 115.277 138.567 166.051 1.00 84.08  ? 131 TYR B OH  1 
ATOM   4175 N N   . TRP B 1 132 ? 123.071 136.819 162.856 1.00 79.77  ? 132 TRP B N   1 
ATOM   4176 C CA  . TRP B 1 132 ? 124.475 136.553 162.575 1.00 77.80  ? 132 TRP B CA  1 
ATOM   4177 C C   . TRP B 1 132 ? 124.998 137.459 161.469 1.00 78.30  ? 132 TRP B C   1 
ATOM   4178 O O   . TRP B 1 132 ? 126.135 137.937 161.539 1.00 88.11  ? 132 TRP B O   1 
ATOM   4179 C CB  . TRP B 1 132 ? 124.664 135.085 162.203 1.00 79.37  ? 132 TRP B CB  1 
ATOM   4180 C CG  . TRP B 1 132 ? 126.089 134.689 162.085 1.00 79.07  ? 132 TRP B CG  1 
ATOM   4181 C CD1 . TRP B 1 132 ? 126.926 134.335 163.098 1.00 78.48  ? 132 TRP B CD1 1 
ATOM   4182 C CD2 . TRP B 1 132 ? 126.857 134.610 160.882 1.00 78.41  ? 132 TRP B CD2 1 
ATOM   4183 N NE1 . TRP B 1 132 ? 128.169 134.037 162.601 1.00 80.99  ? 132 TRP B NE1 1 
ATOM   4184 C CE2 . TRP B 1 132 ? 128.152 134.199 161.241 1.00 81.58  ? 132 TRP B CE2 1 
ATOM   4185 C CE3 . TRP B 1 132 ? 126.574 134.845 159.535 1.00 74.56  ? 132 TRP B CE3 1 
ATOM   4186 C CZ2 . TRP B 1 132 ? 129.162 134.020 160.305 1.00 82.09  ? 132 TRP B CZ2 1 
ATOM   4187 C CZ3 . TRP B 1 132 ? 127.576 134.665 158.609 1.00 79.21  ? 132 TRP B CZ3 1 
ATOM   4188 C CH2 . TRP B 1 132 ? 128.853 134.257 158.997 1.00 78.46  ? 132 TRP B CH2 1 
ATOM   4189 N N   . LEU B 1 133 ? 124.185 137.707 160.440 1.00 83.97  ? 133 LEU B N   1 
ATOM   4190 C CA  . LEU B 1 133 ? 124.607 138.594 159.361 1.00 84.15  ? 133 LEU B CA  1 
ATOM   4191 C C   . LEU B 1 133 ? 124.838 140.009 159.868 1.00 89.70  ? 133 LEU B C   1 
ATOM   4192 O O   . LEU B 1 133 ? 125.798 140.672 159.461 1.00 99.19  ? 133 LEU B O   1 
ATOM   4193 C CB  . LEU B 1 133 ? 123.570 138.589 158.239 1.00 82.28  ? 133 LEU B CB  1 
ATOM   4194 C CG  . LEU B 1 133 ? 123.675 137.423 157.258 1.00 85.35  ? 133 LEU B CG  1 
ATOM   4195 C CD1 . LEU B 1 133 ? 122.474 137.390 156.332 1.00 85.85  ? 133 LEU B CD1 1 
ATOM   4196 C CD2 . LEU B 1 133 ? 124.961 137.526 156.463 1.00 87.59  ? 133 LEU B CD2 1 
ATOM   4197 N N   . ASP B 1 134 ? 123.974 140.491 160.752 1.00 88.29  ? 134 ASP B N   1 
ATOM   4198 C CA  . ASP B 1 134 ? 124.157 141.816 161.324 1.00 89.62  ? 134 ASP B CA  1 
ATOM   4199 C C   . ASP B 1 134 ? 123.567 141.795 162.728 1.00 87.19  ? 134 ASP B C   1 
ATOM   4200 O O   . ASP B 1 134 ? 122.342 141.767 162.884 1.00 93.67  ? 134 ASP B O   1 
ATOM   4201 C CB  . ASP B 1 134 ? 123.494 142.874 160.435 1.00 91.83  ? 134 ASP B CB  1 
ATOM   4202 C CG  . ASP B 1 134 ? 123.547 144.281 161.024 1.00 96.16  ? 134 ASP B CG  1 
ATOM   4203 O OD1 . ASP B 1 134 ? 123.615 144.455 162.256 1.00 92.04  ? 134 ASP B OD1 1 
ATOM   4204 O OD2 . ASP B 1 134 ? 123.519 145.239 160.224 1.00 99.51  ? 134 ASP B OD2 1 
ATOM   4205 N N   . PRO B 1 135 ? 124.401 141.812 163.769 1.00 87.25  ? 135 PRO B N   1 
ATOM   4206 C CA  . PRO B 1 135 ? 123.871 141.707 165.138 1.00 88.97  ? 135 PRO B CA  1 
ATOM   4207 C C   . PRO B 1 135 ? 122.971 142.860 165.546 1.00 94.39  ? 135 PRO B C   1 
ATOM   4208 O O   . PRO B 1 135 ? 122.179 142.699 166.482 1.00 93.66  ? 135 PRO B O   1 
ATOM   4209 C CB  . PRO B 1 135 ? 125.138 141.658 166.003 1.00 91.64  ? 135 PRO B CB  1 
ATOM   4210 C CG  . PRO B 1 135 ? 126.232 141.258 165.066 1.00 94.37  ? 135 PRO B CG  1 
ATOM   4211 C CD  . PRO B 1 135 ? 125.870 141.859 163.750 1.00 92.13  ? 135 PRO B CD  1 
ATOM   4212 N N   . ASN B 1 136 ? 123.060 144.015 164.884 1.00 104.22 ? 136 ASN B N   1 
ATOM   4213 C CA  . ASN B 1 136 ? 122.215 145.145 165.251 1.00 103.56 ? 136 ASN B CA  1 
ATOM   4214 C C   . ASN B 1 136 ? 120.743 144.902 164.955 1.00 102.46 ? 136 ASN B C   1 
ATOM   4215 O O   . ASN B 1 136 ? 119.902 145.675 165.424 1.00 104.95 ? 136 ASN B O   1 
ATOM   4216 C CB  . ASN B 1 136 ? 122.680 146.412 164.532 1.00 100.32 ? 136 ASN B CB  1 
ATOM   4217 C CG  . ASN B 1 136 ? 124.071 146.843 164.952 1.00 103.79 ? 136 ASN B CG  1 
ATOM   4218 O OD1 . ASN B 1 136 ? 124.635 146.312 165.908 1.00 104.90 ? 136 ASN B OD1 1 
ATOM   4219 N ND2 . ASN B 1 136 ? 124.630 147.813 164.241 1.00 101.75 ? 136 ASN B ND2 1 
ATOM   4220 N N   . LEU B 1 137 ? 120.411 143.861 164.189 1.00 91.70  ? 137 LEU B N   1 
ATOM   4221 C CA  . LEU B 1 137 ? 119.010 143.561 163.917 1.00 89.38  ? 137 LEU B CA  1 
ATOM   4222 C C   . LEU B 1 137 ? 118.301 143.016 165.147 1.00 91.71  ? 137 LEU B C   1 
ATOM   4223 O O   . LEU B 1 137 ? 117.079 143.156 165.265 1.00 95.19  ? 137 LEU B O   1 
ATOM   4224 C CB  . LEU B 1 137 ? 118.896 142.564 162.767 1.00 85.09  ? 137 LEU B CB  1 
ATOM   4225 C CG  . LEU B 1 137 ? 119.232 143.105 161.382 1.00 84.25  ? 137 LEU B CG  1 
ATOM   4226 C CD1 . LEU B 1 137 ? 118.910 142.073 160.329 1.00 86.73  ? 137 LEU B CD1 1 
ATOM   4227 C CD2 . LEU B 1 137 ? 118.466 144.385 161.127 1.00 88.44  ? 137 LEU B CD2 1 
ATOM   4228 N N   . ARG B 1 138 ? 119.043 142.393 166.065 1.00 87.77  ? 138 ARG B N   1 
ATOM   4229 C CA  . ARG B 1 138 ? 118.417 141.790 167.236 1.00 87.91  ? 138 ARG B CA  1 
ATOM   4230 C C   . ARG B 1 138 ? 117.700 142.835 168.079 1.00 91.37  ? 138 ARG B C   1 
ATOM   4231 O O   . ARG B 1 138 ? 116.592 142.593 168.572 1.00 92.73  ? 138 ARG B O   1 
ATOM   4232 C CB  . ARG B 1 138 ? 119.466 141.055 168.069 1.00 90.88  ? 138 ARG B CB  1 
ATOM   4233 C CG  . ARG B 1 138 ? 118.950 139.802 168.755 1.00 88.90  ? 138 ARG B CG  1 
ATOM   4234 C CD  . ARG B 1 138 ? 119.851 139.398 169.905 1.00 90.53  ? 138 ARG B CD  1 
ATOM   4235 N NE  . ARG B 1 138 ? 121.241 139.762 169.659 1.00 92.08  ? 138 ARG B NE  1 
ATOM   4236 C CZ  . ARG B 1 138 ? 122.094 139.026 168.961 1.00 92.19  ? 138 ARG B CZ  1 
ATOM   4237 N NH1 . ARG B 1 138 ? 121.733 137.873 168.423 1.00 92.08  ? 138 ARG B NH1 1 
ATOM   4238 N NH2 . ARG B 1 138 ? 123.341 139.457 168.800 1.00 90.89  ? 138 ARG B NH2 1 
ATOM   4239 N N   . TYR B 1 139 ? 118.316 144.005 168.254 1.00 106.06 ? 139 TYR B N   1 
ATOM   4240 C CA  . TYR B 1 139 ? 117.675 145.072 169.014 1.00 106.77 ? 139 TYR B CA  1 
ATOM   4241 C C   . TYR B 1 139 ? 116.422 145.575 168.308 1.00 109.69 ? 139 TYR B C   1 
ATOM   4242 O O   . TYR B 1 139 ? 115.426 145.912 168.960 1.00 109.52 ? 139 TYR B O   1 
ATOM   4243 C CB  . TYR B 1 139 ? 118.663 146.215 169.240 1.00 107.29 ? 139 TYR B CB  1 
ATOM   4244 C CG  . TYR B 1 139 ? 120.021 145.759 169.723 1.00 112.83 ? 139 TYR B CG  1 
ATOM   4245 C CD1 . TYR B 1 139 ? 120.141 144.754 170.676 1.00 112.41 ? 139 TYR B CD1 1 
ATOM   4246 C CD2 . TYR B 1 139 ? 121.185 146.329 169.220 1.00 108.72 ? 139 TYR B CD2 1 
ATOM   4247 C CE1 . TYR B 1 139 ? 121.383 144.333 171.118 1.00 111.20 ? 139 TYR B CE1 1 
ATOM   4248 C CE2 . TYR B 1 139 ? 122.430 145.915 169.656 1.00 111.23 ? 139 TYR B CE2 1 
ATOM   4249 C CZ  . TYR B 1 139 ? 122.523 144.917 170.604 1.00 114.13 ? 139 TYR B CZ  1 
ATOM   4250 O OH  . TYR B 1 139 ? 123.760 144.501 171.040 1.00 111.22 ? 139 TYR B OH  1 
ATOM   4251 N N   . ALA B 1 140 ? 116.454 145.637 166.980 1.00 110.06 ? 140 ALA B N   1 
ATOM   4252 C CA  . ALA B 1 140 ? 115.309 146.091 166.197 1.00 109.67 ? 140 ALA B CA  1 
ATOM   4253 C C   . ALA B 1 140 ? 114.105 145.173 166.388 1.00 110.43 ? 140 ALA B C   1 
ATOM   4254 O O   . ALA B 1 140 ? 114.111 144.024 165.948 1.00 110.48 ? 140 ALA B O   1 
ATOM   4255 C CB  . ALA B 1 140 ? 115.676 146.178 164.724 1.00 101.99 ? 140 ALA B CB  1 
ATOM   4256 N N   . GLU B 1 159 ? 106.016 172.055 151.941 1.00 149.67 ? 159 GLU B N   1 
ATOM   4257 C CA  . GLU B 1 159 ? 105.649 171.626 153.285 1.00 151.38 ? 159 GLU B CA  1 
ATOM   4258 C C   . GLU B 1 159 ? 105.890 170.135 153.475 1.00 151.88 ? 159 GLU B C   1 
ATOM   4259 O O   . GLU B 1 159 ? 107.017 169.655 153.349 1.00 151.90 ? 159 GLU B O   1 
ATOM   4260 C CB  . GLU B 1 159 ? 104.183 171.957 153.574 1.00 149.22 ? 159 GLU B CB  1 
ATOM   4261 C CG  . GLU B 1 159 ? 103.898 173.437 153.761 1.00 149.41 ? 159 GLU B CG  1 
ATOM   4262 C CD  . GLU B 1 159 ? 103.696 174.166 152.449 1.00 150.04 ? 159 GLU B CD  1 
ATOM   4263 O OE1 . GLU B 1 159 ? 103.696 173.502 151.391 1.00 151.44 ? 159 GLU B OE1 1 
ATOM   4264 O OE2 . GLU B 1 159 ? 103.533 175.404 152.476 1.00 148.88 ? 159 GLU B OE2 1 
ATOM   4265 N N   . ARG B 1 160 ? 104.814 169.407 153.784 1.00 150.29 ? 160 ARG B N   1 
ATOM   4266 C CA  . ARG B 1 160 ? 104.908 167.968 153.993 1.00 149.59 ? 160 ARG B CA  1 
ATOM   4267 C C   . ARG B 1 160 ? 105.289 167.224 152.719 1.00 150.78 ? 160 ARG B C   1 
ATOM   4268 O O   . ARG B 1 160 ? 105.830 166.116 152.800 1.00 148.92 ? 160 ARG B O   1 
ATOM   4269 C CB  . ARG B 1 160 ? 103.582 167.443 154.543 1.00 148.46 ? 160 ARG B CB  1 
ATOM   4270 C CG  . ARG B 1 160 ? 103.654 166.062 155.164 1.00 149.25 ? 160 ARG B CG  1 
ATOM   4271 C CD  . ARG B 1 160 ? 102.293 165.638 155.691 1.00 148.80 ? 160 ARG B CD  1 
ATOM   4272 N NE  . ARG B 1 160 ? 102.163 164.188 155.783 1.00 150.16 ? 160 ARG B NE  1 
ATOM   4273 C CZ  . ARG B 1 160 ? 101.083 163.561 156.230 1.00 150.93 ? 160 ARG B CZ  1 
ATOM   4274 N NH1 . ARG B 1 160 ? 100.017 164.228 156.642 1.00 149.55 ? 160 ARG B NH1 1 
ATOM   4275 N NH2 . ARG B 1 160 ? 101.073 162.231 156.264 1.00 150.09 ? 160 ARG B NH2 1 
ATOM   4276 N N   . ILE B 1 161 ? 105.018 167.807 151.549 1.00 154.11 ? 161 ILE B N   1 
ATOM   4277 C CA  . ILE B 1 161 ? 105.421 167.187 150.290 1.00 151.80 ? 161 ILE B CA  1 
ATOM   4278 C C   . ILE B 1 161 ? 106.938 167.099 150.200 1.00 151.31 ? 161 ILE B C   1 
ATOM   4279 O O   . ILE B 1 161 ? 107.494 166.065 149.810 1.00 150.51 ? 161 ILE B O   1 
ATOM   4280 C CB  . ILE B 1 161 ? 104.835 167.968 149.100 1.00 151.52 ? 161 ILE B CB  1 
ATOM   4281 C CG1 . ILE B 1 161 ? 103.384 168.362 149.382 1.00 152.07 ? 161 ILE B CG1 1 
ATOM   4282 C CG2 . ILE B 1 161 ? 104.938 167.152 147.823 1.00 150.46 ? 161 ILE B CG2 1 
ATOM   4283 C CD1 . ILE B 1 161 ? 102.767 169.238 148.312 1.00 152.32 ? 161 ILE B CD1 1 
ATOM   4284 N N   . ILE B 1 162 ? 107.630 168.181 150.560 1.00 153.25 ? 162 ILE B N   1 
ATOM   4285 C CA  . ILE B 1 162 ? 109.081 168.231 150.401 1.00 153.76 ? 162 ILE B CA  1 
ATOM   4286 C C   . ILE B 1 162 ? 109.762 167.247 151.343 1.00 152.87 ? 162 ILE B C   1 
ATOM   4287 O O   . ILE B 1 162 ? 110.773 166.627 150.992 1.00 151.67 ? 162 ILE B O   1 
ATOM   4288 C CB  . ILE B 1 162 ? 109.590 169.668 150.616 1.00 152.19 ? 162 ILE B CB  1 
ATOM   4289 C CG1 . ILE B 1 162 ? 108.689 170.663 149.882 1.00 150.82 ? 162 ILE B CG1 1 
ATOM   4290 C CG2 . ILE B 1 162 ? 111.028 169.800 150.140 1.00 150.34 ? 162 ILE B CG2 1 
ATOM   4291 C CD1 . ILE B 1 162 ? 109.124 172.104 150.029 1.00 151.19 ? 162 ILE B CD1 1 
ATOM   4292 N N   . SER B 1 163 ? 109.222 167.089 152.553 1.00 152.66 ? 163 SER B N   1 
ATOM   4293 C CA  . SER B 1 163 ? 109.880 166.259 153.555 1.00 153.98 ? 163 SER B CA  1 
ATOM   4294 C C   . SER B 1 163 ? 109.909 164.789 153.155 1.00 154.44 ? 163 SER B C   1 
ATOM   4295 O O   . SER B 1 163 ? 110.817 164.055 153.561 1.00 154.03 ? 163 SER B O   1 
ATOM   4296 C CB  . SER B 1 163 ? 109.183 166.423 154.905 1.00 154.18 ? 163 SER B CB  1 
ATOM   4297 O OG  . SER B 1 163 ? 107.863 165.910 154.859 1.00 154.76 ? 163 SER B OG  1 
ATOM   4298 N N   . HIS B 1 164 ? 108.934 164.339 152.363 1.00 150.92 ? 164 HIS B N   1 
ATOM   4299 C CA  . HIS B 1 164 ? 108.833 162.917 152.060 1.00 151.28 ? 164 HIS B CA  1 
ATOM   4300 C C   . HIS B 1 164 ? 109.878 162.448 151.056 1.00 150.35 ? 164 HIS B C   1 
ATOM   4301 O O   . HIS B 1 164 ? 110.173 161.250 151.012 1.00 151.42 ? 164 HIS B O   1 
ATOM   4302 C CB  . HIS B 1 164 ? 107.430 162.587 151.553 1.00 150.38 ? 164 HIS B CB  1 
ATOM   4303 C CG  . HIS B 1 164 ? 106.448 162.308 152.647 1.00 151.97 ? 164 HIS B CG  1 
ATOM   4304 N ND1 . HIS B 1 164 ? 106.272 163.154 153.721 1.00 151.45 ? 164 HIS B ND1 1 
ATOM   4305 C CD2 . HIS B 1 164 ? 105.596 161.274 152.840 1.00 151.64 ? 164 HIS B CD2 1 
ATOM   4306 C CE1 . HIS B 1 164 ? 105.351 162.655 154.526 1.00 149.70 ? 164 HIS B CE1 1 
ATOM   4307 N NE2 . HIS B 1 164 ? 104.924 161.515 154.014 1.00 151.04 ? 164 HIS B NE2 1 
ATOM   4308 N N   . PHE B 1 165 ? 110.439 163.348 150.253 1.00 146.63 ? 165 PHE B N   1 
ATOM   4309 C CA  . PHE B 1 165 ? 111.488 162.956 149.322 1.00 147.37 ? 165 PHE B CA  1 
ATOM   4310 C C   . PHE B 1 165 ? 112.732 162.515 150.080 1.00 146.27 ? 165 PHE B C   1 
ATOM   4311 O O   . PHE B 1 165 ? 113.107 163.113 151.092 1.00 146.29 ? 165 PHE B O   1 
ATOM   4312 C CB  . PHE B 1 165 ? 111.832 164.109 148.381 1.00 146.19 ? 165 PHE B CB  1 
ATOM   4313 C CG  . PHE B 1 165 ? 110.635 164.787 147.788 1.00 148.30 ? 165 PHE B CG  1 
ATOM   4314 C CD1 . PHE B 1 165 ? 109.644 164.050 147.164 1.00 147.76 ? 165 PHE B CD1 1 
ATOM   4315 C CD2 . PHE B 1 165 ? 110.504 166.164 147.844 1.00 147.89 ? 165 PHE B CD2 1 
ATOM   4316 C CE1 . PHE B 1 165 ? 108.542 164.674 146.612 1.00 148.03 ? 165 PHE B CE1 1 
ATOM   4317 C CE2 . PHE B 1 165 ? 109.405 166.793 147.292 1.00 148.24 ? 165 PHE B CE2 1 
ATOM   4318 C CZ  . PHE B 1 165 ? 108.422 166.049 146.678 1.00 148.21 ? 165 PHE B CZ  1 
ATOM   4319 N N   . ASP B 1 166 ? 113.375 161.463 149.587 1.00 128.84 ? 166 ASP B N   1 
ATOM   4320 C CA  . ASP B 1 166 ? 114.541 160.899 150.254 1.00 129.08 ? 166 ASP B CA  1 
ATOM   4321 C C   . ASP B 1 166 ? 115.349 160.108 149.233 1.00 127.60 ? 166 ASP B C   1 
ATOM   4322 O O   . ASP B 1 166 ? 115.055 160.126 148.033 1.00 128.74 ? 166 ASP B O   1 
ATOM   4323 C CB  . ASP B 1 166 ? 114.118 160.037 151.449 1.00 130.85 ? 166 ASP B CB  1 
ATOM   4324 C CG  . ASP B 1 166 ? 112.998 159.077 151.106 1.00 129.23 ? 166 ASP B CG  1 
ATOM   4325 O OD1 . ASP B 1 166 ? 112.151 159.428 150.260 1.00 127.58 ? 166 ASP B OD1 1 
ATOM   4326 O OD2 . ASP B 1 166 ? 112.959 157.975 151.688 1.00 129.73 ? 166 ASP B OD2 1 
ATOM   4327 N N   . ILE B 1 167 ? 116.382 159.414 149.715 1.00 117.22 ? 167 ILE B N   1 
ATOM   4328 C CA  . ILE B 1 167 ? 117.223 158.616 148.830 1.00 119.50 ? 167 ILE B CA  1 
ATOM   4329 C C   . ILE B 1 167 ? 116.435 157.446 148.253 1.00 120.75 ? 167 ILE B C   1 
ATOM   4330 O O   . ILE B 1 167 ? 116.642 157.048 147.101 1.00 120.98 ? 167 ILE B O   1 
ATOM   4331 C CB  . ILE B 1 167 ? 118.484 158.148 149.579 1.00 119.21 ? 167 ILE B CB  1 
ATOM   4332 C CG1 . ILE B 1 167 ? 119.301 157.187 148.719 1.00 118.81 ? 167 ILE B CG1 1 
ATOM   4333 C CG2 . ILE B 1 167 ? 118.112 157.501 150.899 1.00 119.73 ? 167 ILE B CG2 1 
ATOM   4334 C CD1 . ILE B 1 167 ? 120.202 157.879 147.727 1.00 118.79 ? 167 ILE B CD1 1 
ATOM   4335 N N   . PHE B 1 168 ? 115.521 156.877 149.037 1.00 117.79 ? 168 PHE B N   1 
ATOM   4336 C CA  . PHE B 1 168 ? 114.730 155.751 148.556 1.00 117.41 ? 168 PHE B CA  1 
ATOM   4337 C C   . PHE B 1 168 ? 113.656 156.186 147.568 1.00 118.65 ? 168 PHE B C   1 
ATOM   4338 O O   . PHE B 1 168 ? 113.255 155.393 146.710 1.00 117.51 ? 168 PHE B O   1 
ATOM   4339 C CB  . PHE B 1 168 ? 114.120 155.011 149.744 1.00 114.16 ? 168 PHE B CB  1 
ATOM   4340 C CG  . PHE B 1 168 ? 115.070 154.852 150.889 1.00 117.18 ? 168 PHE B CG  1 
ATOM   4341 C CD1 . PHE B 1 168 ? 116.241 154.130 150.733 1.00 117.58 ? 168 PHE B CD1 1 
ATOM   4342 C CD2 . PHE B 1 168 ? 114.810 155.444 152.112 1.00 118.79 ? 168 PHE B CD2 1 
ATOM   4343 C CE1 . PHE B 1 168 ? 117.128 153.988 151.779 1.00 117.49 ? 168 PHE B CE1 1 
ATOM   4344 C CE2 . PHE B 1 168 ? 115.694 155.307 153.163 1.00 118.98 ? 168 PHE B CE2 1 
ATOM   4345 C CZ  . PHE B 1 168 ? 116.855 154.577 152.996 1.00 117.72 ? 168 PHE B CZ  1 
ATOM   4346 N N   . ALA B 1 169 ? 113.178 157.427 147.668 1.00 114.95 ? 169 ALA B N   1 
ATOM   4347 C CA  . ALA B 1 169 ? 112.339 157.968 146.604 1.00 111.76 ? 169 ALA B CA  1 
ATOM   4348 C C   . ALA B 1 169 ? 113.136 158.111 145.316 1.00 110.80 ? 169 ALA B C   1 
ATOM   4349 O O   . ALA B 1 169 ? 112.601 157.920 144.218 1.00 111.28 ? 169 ALA B O   1 
ATOM   4350 C CB  . ALA B 1 169 ? 111.748 159.312 147.026 1.00 114.39 ? 169 ALA B CB  1 
ATOM   4351 N N   . PHE B 1 170 ? 114.417 158.461 145.434 1.00 114.12 ? 170 PHE B N   1 
ATOM   4352 C CA  . PHE B 1 170 ? 115.311 158.452 144.281 1.00 112.21 ? 170 PHE B CA  1 
ATOM   4353 C C   . PHE B 1 170 ? 115.438 157.048 143.707 1.00 112.45 ? 170 PHE B C   1 
ATOM   4354 O O   . PHE B 1 170 ? 115.391 156.855 142.487 1.00 112.99 ? 170 PHE B O   1 
ATOM   4355 C CB  . PHE B 1 170 ? 116.679 158.995 144.694 1.00 112.13 ? 170 PHE B CB  1 
ATOM   4356 C CG  . PHE B 1 170 ? 117.558 159.386 143.546 1.00 113.15 ? 170 PHE B CG  1 
ATOM   4357 C CD1 . PHE B 1 170 ? 117.248 160.479 142.757 1.00 114.97 ? 170 PHE B CD1 1 
ATOM   4358 C CD2 . PHE B 1 170 ? 118.708 158.667 143.267 1.00 113.86 ? 170 PHE B CD2 1 
ATOM   4359 C CE1 . PHE B 1 170 ? 118.067 160.841 141.704 1.00 116.49 ? 170 PHE B CE1 1 
ATOM   4360 C CE2 . PHE B 1 170 ? 119.529 159.024 142.217 1.00 113.13 ? 170 PHE B CE2 1 
ATOM   4361 C CZ  . PHE B 1 170 ? 119.210 160.113 141.436 1.00 113.87 ? 170 PHE B CZ  1 
ATOM   4362 N N   . GLY B 1 171 ? 115.607 156.051 144.576 1.00 109.99 ? 171 GLY B N   1 
ATOM   4363 C CA  . GLY B 1 171 ? 115.688 154.678 144.105 1.00 109.21 ? 171 GLY B CA  1 
ATOM   4364 C C   . GLY B 1 171 ? 114.383 154.177 143.517 1.00 113.63 ? 171 GLY B C   1 
ATOM   4365 O O   . GLY B 1 171 ? 114.372 153.543 142.459 1.00 112.61 ? 171 GLY B O   1 
ATOM   4366 N N   . HIS B 1 172 ? 113.265 154.454 144.193 1.00 109.89 ? 172 HIS B N   1 
ATOM   4367 C CA  . HIS B 1 172 ? 111.968 154.005 143.699 1.00 104.28 ? 172 HIS B CA  1 
ATOM   4368 C C   . HIS B 1 172 ? 111.658 154.622 142.343 1.00 99.70  ? 172 HIS B C   1 
ATOM   4369 O O   . HIS B 1 172 ? 111.104 153.957 141.462 1.00 99.92  ? 172 HIS B O   1 
ATOM   4370 C CB  . HIS B 1 172 ? 110.875 154.352 144.709 1.00 103.94 ? 172 HIS B CB  1 
ATOM   4371 C CG  . HIS B 1 172 ? 109.709 153.415 144.685 1.00 108.08 ? 172 HIS B CG  1 
ATOM   4372 N ND1 . HIS B 1 172 ? 109.080 153.038 143.519 1.00 109.93 ? 172 HIS B ND1 1 
ATOM   4373 C CD2 . HIS B 1 172 ? 109.060 152.775 145.686 1.00 109.65 ? 172 HIS B CD2 1 
ATOM   4374 C CE1 . HIS B 1 172 ? 108.092 152.208 143.803 1.00 106.92 ? 172 HIS B CE1 1 
ATOM   4375 N NE2 . HIS B 1 172 ? 108.058 152.031 145.111 1.00 110.68 ? 172 HIS B NE2 1 
ATOM   4376 N N   . PHE B 1 173 ? 112.004 155.896 142.164 1.00 93.26  ? 173 PHE B N   1 
ATOM   4377 C CA  . PHE B 1 173 ? 111.839 156.542 140.868 1.00 91.55  ? 173 PHE B CA  1 
ATOM   4378 C C   . PHE B 1 173 ? 112.718 155.879 139.815 1.00 93.28  ? 173 PHE B C   1 
ATOM   4379 O O   . PHE B 1 173 ? 112.242 155.505 138.738 1.00 97.16  ? 173 PHE B O   1 
ATOM   4380 C CB  . PHE B 1 173 ? 112.163 158.032 140.999 1.00 93.87  ? 173 PHE B CB  1 
ATOM   4381 C CG  . PHE B 1 173 ? 112.543 158.700 139.709 1.00 90.97  ? 173 PHE B CG  1 
ATOM   4382 C CD1 . PHE B 1 173 ? 111.583 159.306 138.927 1.00 92.32  ? 173 PHE B CD1 1 
ATOM   4383 C CD2 . PHE B 1 173 ? 113.862 158.755 139.298 1.00 93.39  ? 173 PHE B CD2 1 
ATOM   4384 C CE1 . PHE B 1 173 ? 111.923 159.932 137.751 1.00 91.55  ? 173 PHE B CE1 1 
ATOM   4385 C CE2 . PHE B 1 173 ? 114.206 159.373 138.121 1.00 94.52  ? 173 PHE B CE2 1 
ATOM   4386 C CZ  . PHE B 1 173 ? 113.234 159.964 137.348 1.00 93.98  ? 173 PHE B CZ  1 
ATOM   4387 N N   . TRP B 1 174 ? 114.008 155.713 140.117 1.00 96.01  ? 174 TRP B N   1 
ATOM   4388 C CA  . TRP B 1 174 ? 114.928 155.160 139.129 1.00 94.39  ? 174 TRP B CA  1 
ATOM   4389 C C   . TRP B 1 174 ? 114.656 153.687 138.867 1.00 96.33  ? 174 TRP B C   1 
ATOM   4390 O O   . TRP B 1 174 ? 114.924 153.199 137.765 1.00 96.58  ? 174 TRP B O   1 
ATOM   4391 C CB  . TRP B 1 174 ? 116.371 155.369 139.577 1.00 93.15  ? 174 TRP B CB  1 
ATOM   4392 C CG  . TRP B 1 174 ? 116.942 156.661 139.097 1.00 95.56  ? 174 TRP B CG  1 
ATOM   4393 C CD1 . TRP B 1 174 ? 117.207 157.769 139.845 1.00 97.76  ? 174 TRP B CD1 1 
ATOM   4394 C CD2 . TRP B 1 174 ? 117.313 156.985 137.754 1.00 96.79  ? 174 TRP B CD2 1 
ATOM   4395 N NE1 . TRP B 1 174 ? 117.721 158.763 139.051 1.00 94.66  ? 174 TRP B NE1 1 
ATOM   4396 C CE2 . TRP B 1 174 ? 117.798 158.307 137.762 1.00 96.88  ? 174 TRP B CE2 1 
ATOM   4397 C CE3 . TRP B 1 174 ? 117.284 156.286 136.545 1.00 99.82  ? 174 TRP B CE3 1 
ATOM   4398 C CZ2 . TRP B 1 174 ? 118.248 158.942 136.611 1.00 98.23  ? 174 TRP B CZ2 1 
ATOM   4399 C CZ3 . TRP B 1 174 ? 117.733 156.919 135.402 1.00 97.72  ? 174 TRP B CZ3 1 
ATOM   4400 C CH2 . TRP B 1 174 ? 118.208 158.233 135.443 1.00 97.63  ? 174 TRP B CH2 1 
ATOM   4401 N N   . GLY B 1 175 ? 114.138 152.963 139.858 1.00 89.13  ? 175 GLY B N   1 
ATOM   4402 C CA  . GLY B 1 175 ? 113.687 151.608 139.598 1.00 87.58  ? 175 GLY B CA  1 
ATOM   4403 C C   . GLY B 1 175 ? 112.532 151.571 138.618 1.00 89.23  ? 175 GLY B C   1 
ATOM   4404 O O   . GLY B 1 175 ? 112.483 150.717 137.731 1.00 88.43  ? 175 GLY B O   1 
ATOM   4405 N N   . TRP B 1 176 ? 111.586 152.501 138.764 1.00 86.72  ? 176 TRP B N   1 
ATOM   4406 C CA  . TRP B 1 176 ? 110.483 152.593 137.816 1.00 80.11  ? 176 TRP B CA  1 
ATOM   4407 C C   . TRP B 1 176 ? 110.969 153.033 136.444 1.00 79.70  ? 176 TRP B C   1 
ATOM   4408 O O   . TRP B 1 176 ? 110.462 152.560 135.420 1.00 82.75  ? 176 TRP B O   1 
ATOM   4409 C CB  . TRP B 1 176 ? 109.415 153.548 138.341 1.00 77.41  ? 176 TRP B CB  1 
ATOM   4410 C CG  . TRP B 1 176 ? 108.311 152.849 139.052 1.00 79.20  ? 176 TRP B CG  1 
ATOM   4411 C CD1 . TRP B 1 176 ? 107.909 153.049 140.334 1.00 81.21  ? 176 TRP B CD1 1 
ATOM   4412 C CD2 . TRP B 1 176 ? 107.465 151.826 138.520 1.00 79.10  ? 176 TRP B CD2 1 
ATOM   4413 N NE1 . TRP B 1 176 ? 106.863 152.216 140.638 1.00 83.66  ? 176 TRP B NE1 1 
ATOM   4414 C CE2 . TRP B 1 176 ? 106.571 151.455 139.538 1.00 81.91  ? 176 TRP B CE2 1 
ATOM   4415 C CE3 . TRP B 1 176 ? 107.375 151.190 137.281 1.00 76.96  ? 176 TRP B CE3 1 
ATOM   4416 C CZ2 . TRP B 1 176 ? 105.604 150.479 139.357 1.00 80.08  ? 176 TRP B CZ2 1 
ATOM   4417 C CZ3 . TRP B 1 176 ? 106.417 150.223 137.104 1.00 77.64  ? 176 TRP B CZ3 1 
ATOM   4418 C CH2 . TRP B 1 176 ? 105.543 149.876 138.134 1.00 82.39  ? 176 TRP B CH2 1 
ATOM   4419 N N   . ALA B 1 177 ? 111.942 153.945 136.401 1.00 77.22  ? 177 ALA B N   1 
ATOM   4420 C CA  . ALA B 1 177 ? 112.504 154.355 135.120 1.00 77.94  ? 177 ALA B CA  1 
ATOM   4421 C C   . ALA B 1 177 ? 113.177 153.186 134.419 1.00 80.11  ? 177 ALA B C   1 
ATOM   4422 O O   . ALA B 1 177 ? 113.031 153.016 133.204 1.00 83.88  ? 177 ALA B O   1 
ATOM   4423 C CB  . ALA B 1 177 ? 113.492 155.501 135.320 1.00 76.91  ? 177 ALA B CB  1 
ATOM   4424 N N   . MET B 1 178 ? 113.913 152.364 135.167 1.00 79.78  ? 178 MET B N   1 
ATOM   4425 C CA  . MET B 1 178 ? 114.592 151.225 134.561 1.00 83.34  ? 178 MET B CA  1 
ATOM   4426 C C   . MET B 1 178 ? 113.593 150.223 133.996 1.00 86.13  ? 178 MET B C   1 
ATOM   4427 O O   . MET B 1 178 ? 113.801 149.679 132.906 1.00 82.15  ? 178 MET B O   1 
ATOM   4428 C CB  . MET B 1 178 ? 115.508 150.554 135.585 1.00 80.77  ? 178 MET B CB  1 
ATOM   4429 C CG  . MET B 1 178 ? 116.545 149.624 134.980 1.00 82.37  ? 178 MET B CG  1 
ATOM   4430 S SD  . MET B 1 178 ? 115.979 147.918 134.847 1.00 93.61  ? 178 MET B SD  1 
ATOM   4431 C CE  . MET B 1 178 ? 115.321 147.649 136.489 1.00 80.09  ? 178 MET B CE  1 
ATOM   4432 N N   . LYS B 1 179 ? 112.501 149.965 134.720 1.00 82.06  ? 179 LYS B N   1 
ATOM   4433 C CA  . LYS B 1 179 ? 111.500 149.025 134.226 1.00 76.69  ? 179 LYS B CA  1 
ATOM   4434 C C   . LYS B 1 179 ? 110.901 149.506 132.915 1.00 78.41  ? 179 LYS B C   1 
ATOM   4435 O O   . LYS B 1 179 ? 110.699 148.712 131.991 1.00 85.51  ? 179 LYS B O   1 
ATOM   4436 C CB  . LYS B 1 179 ? 110.399 148.819 135.264 1.00 77.42  ? 179 LYS B CB  1 
ATOM   4437 C CG  . LYS B 1 179 ? 110.850 148.152 136.547 1.00 79.93  ? 179 LYS B CG  1 
ATOM   4438 C CD  . LYS B 1 179 ? 109.975 148.583 137.711 1.00 76.18  ? 179 LYS B CD  1 
ATOM   4439 C CE  . LYS B 1 179 ? 110.464 148.001 139.020 1.00 78.11  ? 179 LYS B CE  1 
ATOM   4440 N NZ  . LYS B 1 179 ? 109.708 148.553 140.176 1.00 77.97  ? 179 LYS B NZ  1 
ATOM   4441 N N   . ALA B 1 180 ? 110.623 150.808 132.811 1.00 76.62  ? 180 ALA B N   1 
ATOM   4442 C CA  . ALA B 1 180 ? 109.979 151.340 131.615 1.00 76.40  ? 180 ALA B CA  1 
ATOM   4443 C C   . ALA B 1 180 ? 110.799 151.078 130.360 1.00 78.22  ? 180 ALA B C   1 
ATOM   4444 O O   . ALA B 1 180 ? 110.231 150.905 129.276 1.00 73.41  ? 180 ALA B O   1 
ATOM   4445 C CB  . ALA B 1 180 ? 109.729 152.837 131.781 1.00 73.65  ? 180 ALA B CB  1 
ATOM   4446 N N   . LEU B 1 181 ? 112.129 151.046 130.479 1.00 76.18  ? 181 LEU B N   1 
ATOM   4447 C CA  . LEU B 1 181 ? 112.962 150.730 129.324 1.00 74.34  ? 181 LEU B CA  1 
ATOM   4448 C C   . LEU B 1 181 ? 112.702 149.319 128.821 1.00 78.51  ? 181 LEU B C   1 
ATOM   4449 O O   . LEU B 1 181 ? 112.624 149.086 127.610 1.00 76.69  ? 181 LEU B O   1 
ATOM   4450 C CB  . LEU B 1 181 ? 114.442 150.895 129.665 1.00 70.27  ? 181 LEU B CB  1 
ATOM   4451 C CG  . LEU B 1 181 ? 115.096 152.261 129.464 1.00 71.52  ? 181 LEU B CG  1 
ATOM   4452 C CD1 . LEU B 1 181 ? 114.648 153.244 130.517 1.00 75.48  ? 181 LEU B CD1 1 
ATOM   4453 C CD2 . LEU B 1 181 ? 116.607 152.117 129.474 1.00 74.91  ? 181 LEU B CD2 1 
ATOM   4454 N N   . LEU B 1 182 ? 112.566 148.363 129.732 1.00 74.57  ? 182 LEU B N   1 
ATOM   4455 C CA  . LEU B 1 182 ? 112.472 146.967 129.338 1.00 71.55  ? 182 LEU B CA  1 
ATOM   4456 C C   . LEU B 1 182 ? 111.068 146.553 128.922 1.00 75.43  ? 182 LEU B C   1 
ATOM   4457 O O   . LEU B 1 182 ? 110.916 145.532 128.243 1.00 78.48  ? 182 LEU B O   1 
ATOM   4458 C CB  . LEU B 1 182 ? 112.950 146.065 130.479 1.00 69.05  ? 182 LEU B CB  1 
ATOM   4459 C CG  . LEU B 1 182 ? 114.461 145.938 130.685 1.00 72.36  ? 182 LEU B CG  1 
ATOM   4460 C CD1 . LEU B 1 182 ? 115.138 145.567 129.381 1.00 72.28  ? 182 LEU B CD1 1 
ATOM   4461 C CD2 . LEU B 1 182 ? 115.069 147.189 131.282 1.00 72.02  ? 182 LEU B CD2 1 
ATOM   4462 N N   . ILE B 1 183 ? 110.048 147.316 129.297 1.00 69.47  ? 183 ILE B N   1 
ATOM   4463 C CA  . ILE B 1 183 ? 108.663 146.980 128.985 1.00 63.93  ? 183 ILE B CA  1 
ATOM   4464 C C   . ILE B 1 183 ? 108.168 147.735 127.761 1.00 64.31  ? 183 ILE B C   1 
ATOM   4465 O O   . ILE B 1 183 ? 107.612 147.137 126.840 1.00 71.17  ? 183 ILE B O   1 
ATOM   4466 C CB  . ILE B 1 183 ? 107.760 147.251 130.208 1.00 66.64  ? 183 ILE B CB  1 
ATOM   4467 C CG1 . ILE B 1 183 ? 108.391 146.689 131.478 1.00 62.42  ? 183 ILE B CG1 1 
ATOM   4468 C CG2 . ILE B 1 183 ? 106.400 146.642 130.005 1.00 69.81  ? 183 ILE B CG2 1 
ATOM   4469 C CD1 . ILE B 1 183 ? 108.644 145.226 131.427 1.00 63.28  ? 183 ILE B CD1 1 
ATOM   4470 N N   . ARG B 1 184 ? 108.373 149.050 127.738 1.00 68.58  ? 184 ARG B N   1 
ATOM   4471 C CA  . ARG B 1 184 ? 107.879 149.944 126.690 1.00 77.43  ? 184 ARG B CA  1 
ATOM   4472 C C   . ARG B 1 184 ? 106.386 149.675 126.458 1.00 82.55  ? 184 ARG B C   1 
ATOM   4473 O O   . ARG B 1 184 ? 105.949 149.062 125.485 1.00 86.57  ? 184 ARG B O   1 
ATOM   4474 C CB  . ARG B 1 184 ? 108.766 149.833 125.434 1.00 77.74  ? 184 ARG B CB  1 
ATOM   4475 C CG  . ARG B 1 184 ? 108.160 149.930 124.014 1.00 76.39  ? 184 ARG B CG  1 
ATOM   4476 C CD  . ARG B 1 184 ? 107.269 151.164 123.805 1.00 78.98  ? 184 ARG B CD  1 
ATOM   4477 N NE  . ARG B 1 184 ? 107.039 151.457 122.396 1.00 86.98  ? 184 ARG B NE  1 
ATOM   4478 C CZ  . ARG B 1 184 ? 107.950 151.961 121.577 1.00 84.70  ? 184 ARG B CZ  1 
ATOM   4479 N NH1 . ARG B 1 184 ? 109.153 152.299 122.007 1.00 83.48  ? 184 ARG B NH1 1 
ATOM   4480 N NH2 . ARG B 1 184 ? 107.641 152.143 120.297 1.00 80.66  ? 184 ARG B NH2 1 
ATOM   4481 N N   . SER B 1 185 ? 105.621 150.054 127.476 1.00 73.94  ? 185 SER B N   1 
ATOM   4482 C CA  . SER B 1 185 ? 104.178 150.193 127.360 1.00 70.00  ? 185 SER B CA  1 
ATOM   4483 C C   . SER B 1 185 ? 103.639 150.934 128.572 1.00 68.57  ? 185 SER B C   1 
ATOM   4484 O O   . SER B 1 185 ? 103.885 150.526 129.709 1.00 68.91  ? 185 SER B O   1 
ATOM   4485 C CB  . SER B 1 185 ? 103.503 148.833 127.234 1.00 69.49  ? 185 SER B CB  1 
ATOM   4486 O OG  . SER B 1 185 ? 103.026 148.421 128.492 1.00 72.85  ? 185 SER B OG  1 
ATOM   4487 N N   . TYR B 1 186 ? 102.913 152.028 128.347 1.00 71.58  ? 186 TYR B N   1 
ATOM   4488 C CA  . TYR B 1 186 ? 102.277 152.712 129.465 1.00 71.56  ? 186 TYR B CA  1 
ATOM   4489 C C   . TYR B 1 186 ? 101.177 151.860 130.078 1.00 70.64  ? 186 TYR B C   1 
ATOM   4490 O O   . TYR B 1 186 ? 100.951 151.921 131.289 1.00 74.12  ? 186 TYR B O   1 
ATOM   4491 C CB  . TYR B 1 186 ? 101.710 154.055 129.013 1.00 73.23  ? 186 TYR B CB  1 
ATOM   4492 C CG  . TYR B 1 186 ? 102.744 155.110 128.698 1.00 72.92  ? 186 TYR B CG  1 
ATOM   4493 C CD1 . TYR B 1 186 ? 103.342 155.170 127.451 1.00 69.53  ? 186 TYR B CD1 1 
ATOM   4494 C CD2 . TYR B 1 186 ? 103.102 156.062 129.639 1.00 75.81  ? 186 TYR B CD2 1 
ATOM   4495 C CE1 . TYR B 1 186 ? 104.276 156.138 127.154 1.00 72.02  ? 186 TYR B CE1 1 
ATOM   4496 C CE2 . TYR B 1 186 ? 104.035 157.035 129.351 1.00 74.73  ? 186 TYR B CE2 1 
ATOM   4497 C CZ  . TYR B 1 186 ? 104.617 157.068 128.106 1.00 72.25  ? 186 TYR B CZ  1 
ATOM   4498 O OH  . TYR B 1 186 ? 105.547 158.034 127.809 1.00 68.59  ? 186 TYR B OH  1 
ATOM   4499 N N   . GLY B 1 187 ? 100.499 151.054 129.272 1.00 71.50  ? 187 GLY B N   1 
ATOM   4500 C CA  . GLY B 1 187 ? 99.407  150.239 129.758 1.00 70.71  ? 187 GLY B CA  1 
ATOM   4501 C C   . GLY B 1 187 ? 99.812  149.064 130.613 1.00 72.53  ? 187 GLY B C   1 
ATOM   4502 O O   . GLY B 1 187 ? 98.937  148.324 131.070 1.00 77.78  ? 187 GLY B O   1 
ATOM   4503 N N   . LEU B 1 188 ? 101.110 148.852 130.821 1.00 67.93  ? 188 LEU B N   1 
ATOM   4504 C CA  . LEU B 1 188 ? 101.610 147.895 131.796 1.00 63.47  ? 188 LEU B CA  1 
ATOM   4505 C C   . LEU B 1 188 ? 102.264 148.582 132.982 1.00 62.36  ? 188 LEU B C   1 
ATOM   4506 O O   . LEU B 1 188 ? 101.898 148.321 134.130 1.00 72.28  ? 188 LEU B O   1 
ATOM   4507 C CB  . LEU B 1 188 ? 102.615 146.932 131.150 1.00 59.31  ? 188 LEU B CB  1 
ATOM   4508 C CG  . LEU B 1 188 ? 102.125 145.956 130.085 1.00 62.65  ? 188 LEU B CG  1 
ATOM   4509 C CD1 . LEU B 1 188 ? 103.062 144.770 130.003 1.00 68.14  ? 188 LEU B CD1 1 
ATOM   4510 C CD2 . LEU B 1 188 ? 100.708 145.509 130.368 1.00 66.15  ? 188 LEU B CD2 1 
ATOM   4511 N N   . CYS B 1 189 ? 103.221 149.473 132.727 1.00 66.03  ? 189 CYS B N   1 
ATOM   4512 C CA  . CYS B 1 189 ? 103.920 150.145 133.811 1.00 66.79  ? 189 CYS B CA  1 
ATOM   4513 C C   . CYS B 1 189 ? 102.996 151.018 134.646 1.00 71.92  ? 189 CYS B C   1 
ATOM   4514 O O   . CYS B 1 189 ? 103.319 151.304 135.801 1.00 78.92  ? 189 CYS B O   1 
ATOM   4515 C CB  . CYS B 1 189 ? 105.066 150.985 133.251 1.00 74.51  ? 189 CYS B CB  1 
ATOM   4516 S SG  . CYS B 1 189 ? 106.451 150.026 132.609 1.00 84.62  ? 189 CYS B SG  1 
ATOM   4517 N N   . TRP B 1 190 ? 101.862 151.452 134.097 1.00 71.45  ? 190 TRP B N   1 
ATOM   4518 C CA  . TRP B 1 190 ? 100.911 152.241 134.872 1.00 68.12  ? 190 TRP B CA  1 
ATOM   4519 C C   . TRP B 1 190 ? 99.857  151.374 135.545 1.00 68.51  ? 190 TRP B C   1 
ATOM   4520 O O   . TRP B 1 190 ? 99.408  151.696 136.648 1.00 74.27  ? 190 TRP B O   1 
ATOM   4521 C CB  . TRP B 1 190 ? 100.226 153.280 133.985 1.00 67.28  ? 190 TRP B CB  1 
ATOM   4522 C CG  . TRP B 1 190 ? 100.859 154.624 134.048 1.00 67.71  ? 190 TRP B CG  1 
ATOM   4523 C CD1 . TRP B 1 190 ? 101.812 155.116 133.214 1.00 71.41  ? 190 TRP B CD1 1 
ATOM   4524 C CD2 . TRP B 1 190 ? 100.585 155.655 134.999 1.00 69.37  ? 190 TRP B CD2 1 
ATOM   4525 N NE1 . TRP B 1 190 ? 102.152 156.391 133.584 1.00 74.72  ? 190 TRP B NE1 1 
ATOM   4526 C CE2 . TRP B 1 190 ? 101.410 156.745 134.679 1.00 73.06  ? 190 TRP B CE2 1 
ATOM   4527 C CE3 . TRP B 1 190 ? 99.722  155.762 136.090 1.00 73.45  ? 190 TRP B CE3 1 
ATOM   4528 C CZ2 . TRP B 1 190 ? 101.400 157.926 135.410 1.00 73.06  ? 190 TRP B CZ2 1 
ATOM   4529 C CZ3 . TRP B 1 190 ? 99.713  156.934 136.814 1.00 74.43  ? 190 TRP B CZ3 1 
ATOM   4530 C CH2 . TRP B 1 190 ? 100.545 158.001 136.471 1.00 76.95  ? 190 TRP B CH2 1 
ATOM   4531 N N   . THR B 1 191 ? 99.444  150.283 134.897 1.00 64.56  ? 191 THR B N   1 
ATOM   4532 C CA  . THR B 1 191 ? 98.506  149.366 135.533 1.00 68.73  ? 191 THR B CA  1 
ATOM   4533 C C   . THR B 1 191 ? 99.106  148.767 136.791 1.00 74.88  ? 191 THR B C   1 
ATOM   4534 O O   . THR B 1 191 ? 98.432  148.643 137.818 1.00 79.07  ? 191 THR B O   1 
ATOM   4535 C CB  . THR B 1 191 ? 98.114  148.257 134.564 1.00 67.77  ? 191 THR B CB  1 
ATOM   4536 O OG1 . THR B 1 191 ? 97.540  148.836 133.388 1.00 87.96  ? 191 THR B OG1 1 
ATOM   4537 C CG2 . THR B 1 191 ? 97.111  147.325 135.208 1.00 66.25  ? 191 THR B CG2 1 
ATOM   4538 N N   . ILE B 1 192 ? 100.380 148.393 136.726 1.00 68.32  ? 192 ILE B N   1 
ATOM   4539 C CA  . ILE B 1 192 ? 101.037 147.755 137.858 1.00 61.50  ? 192 ILE B CA  1 
ATOM   4540 C C   . ILE B 1 192 ? 101.462 148.792 138.888 1.00 65.45  ? 192 ILE B C   1 
ATOM   4541 O O   . ILE B 1 192 ? 101.482 148.519 140.093 1.00 78.99  ? 192 ILE B O   1 
ATOM   4542 C CB  . ILE B 1 192 ? 102.205 146.904 137.339 1.00 50.65  ? 192 ILE B CB  1 
ATOM   4543 C CG1 . ILE B 1 192 ? 101.602 145.693 136.634 1.00 57.55  ? 192 ILE B CG1 1 
ATOM   4544 C CG2 . ILE B 1 192 ? 103.131 146.507 138.462 1.00 58.25  ? 192 ILE B CG2 1 
ATOM   4545 C CD1 . ILE B 1 192 ? 102.357 145.194 135.479 1.00 68.65  ? 192 ILE B CD1 1 
ATOM   4546 N N   . SER B 1 193 ? 101.788 150.003 138.439 1.00 57.30  ? 193 SER B N   1 
ATOM   4547 C CA  . SER B 1 193 ? 102.044 151.082 139.384 1.00 55.67  ? 193 SER B CA  1 
ATOM   4548 C C   . SER B 1 193 ? 100.786 151.451 140.156 1.00 60.83  ? 193 SER B C   1 
ATOM   4549 O O   . SER B 1 193 ? 100.837 151.670 141.370 1.00 75.88  ? 193 SER B O   1 
ATOM   4550 C CB  . SER B 1 193 ? 102.592 152.304 138.657 1.00 64.44  ? 193 SER B CB  1 
ATOM   4551 O OG  . SER B 1 193 ? 102.588 153.433 139.508 1.00 73.13  ? 193 SER B OG  1 
ATOM   4552 N N   . ILE B 1 194 ? 99.648  151.544 139.469 1.00 54.80  ? 194 ILE B N   1 
ATOM   4553 C CA  . ILE B 1 194 ? 98.416  151.945 140.141 1.00 64.33  ? 194 ILE B CA  1 
ATOM   4554 C C   . ILE B 1 194 ? 97.908  150.836 141.051 1.00 72.45  ? 194 ILE B C   1 
ATOM   4555 O O   . ILE B 1 194 ? 97.509  151.089 142.192 1.00 83.03  ? 194 ILE B O   1 
ATOM   4556 C CB  . ILE B 1 194 ? 97.351  152.363 139.114 1.00 67.37  ? 194 ILE B CB  1 
ATOM   4557 C CG1 . ILE B 1 194 ? 97.664  153.753 138.564 1.00 72.54  ? 194 ILE B CG1 1 
ATOM   4558 C CG2 . ILE B 1 194 ? 95.973  152.348 139.743 1.00 65.82  ? 194 ILE B CG2 1 
ATOM   4559 C CD1 . ILE B 1 194 ? 96.585  154.309 137.663 1.00 71.67  ? 194 ILE B CD1 1 
ATOM   4560 N N   . THR B 1 195 ? 97.908  149.594 140.569 1.00 63.12  ? 195 THR B N   1 
ATOM   4561 C CA  . THR B 1 195 ? 97.290  148.526 141.343 1.00 65.59  ? 195 THR B CA  1 
ATOM   4562 C C   . THR B 1 195 ? 98.154  148.085 142.517 1.00 63.31  ? 195 THR B C   1 
ATOM   4563 O O   . THR B 1 195 ? 97.619  147.604 143.519 1.00 73.12  ? 195 THR B O   1 
ATOM   4564 C CB  . THR B 1 195 ? 96.960  147.335 140.440 1.00 68.94  ? 195 THR B CB  1 
ATOM   4565 O OG1 . THR B 1 195 ? 95.947  146.536 141.059 1.00 77.69  ? 195 THR B OG1 1 
ATOM   4566 C CG2 . THR B 1 195 ? 98.183  146.477 140.195 1.00 65.16  ? 195 THR B CG2 1 
ATOM   4567 N N   . TRP B 1 196 ? 99.476  148.233 142.428 1.00 56.99  ? 196 TRP B N   1 
ATOM   4568 C CA  . TRP B 1 196 ? 100.317 147.884 143.567 1.00 60.35  ? 196 TRP B CA  1 
ATOM   4569 C C   . TRP B 1 196 ? 100.231 148.942 144.659 1.00 63.91  ? 196 TRP B C   1 
ATOM   4570 O O   . TRP B 1 196 ? 100.132 148.614 145.847 1.00 72.22  ? 196 TRP B O   1 
ATOM   4571 C CB  . TRP B 1 196 ? 101.766 147.692 143.131 1.00 60.46  ? 196 TRP B CB  1 
ATOM   4572 C CG  . TRP B 1 196 ? 102.711 147.747 144.277 1.00 60.63  ? 196 TRP B CG  1 
ATOM   4573 C CD1 . TRP B 1 196 ? 103.697 148.661 144.478 1.00 61.77  ? 196 TRP B CD1 1 
ATOM   4574 C CD2 . TRP B 1 196 ? 102.753 146.858 145.397 1.00 66.79  ? 196 TRP B CD2 1 
ATOM   4575 N NE1 . TRP B 1 196 ? 104.358 148.395 145.649 1.00 58.43  ? 196 TRP B NE1 1 
ATOM   4576 C CE2 . TRP B 1 196 ? 103.794 147.292 146.234 1.00 66.66  ? 196 TRP B CE2 1 
ATOM   4577 C CE3 . TRP B 1 196 ? 102.013 145.734 145.771 1.00 68.01  ? 196 TRP B CE3 1 
ATOM   4578 C CZ2 . TRP B 1 196 ? 104.114 146.645 147.421 1.00 72.06  ? 196 TRP B CZ2 1 
ATOM   4579 C CZ3 . TRP B 1 196 ? 102.332 145.094 146.950 1.00 59.48  ? 196 TRP B CZ3 1 
ATOM   4580 C CH2 . TRP B 1 196 ? 103.372 145.550 147.760 1.00 66.31  ? 196 TRP B CH2 1 
ATOM   4581 N N   . GLU B 1 197 ? 100.264 150.220 144.277 1.00 72.32  ? 197 GLU B N   1 
ATOM   4582 C CA  . GLU B 1 197 ? 100.203 151.285 145.271 1.00 76.88  ? 197 GLU B CA  1 
ATOM   4583 C C   . GLU B 1 197 ? 98.913  151.222 146.073 1.00 78.45  ? 197 GLU B C   1 
ATOM   4584 O O   . GLU B 1 197 ? 98.897  151.599 147.249 1.00 83.06  ? 197 GLU B O   1 
ATOM   4585 C CB  . GLU B 1 197 ? 100.342 152.648 144.597 1.00 77.87  ? 197 GLU B CB  1 
ATOM   4586 C CG  . GLU B 1 197 ? 101.748 152.974 144.130 1.00 78.87  ? 197 GLU B CG  1 
ATOM   4587 C CD  . GLU B 1 197 ? 102.803 152.629 145.156 1.00 84.98  ? 197 GLU B CD  1 
ATOM   4588 O OE1 . GLU B 1 197 ? 102.677 153.068 146.317 1.00 86.75  ? 197 GLU B OE1 1 
ATOM   4589 O OE2 . GLU B 1 197 ? 103.766 151.920 144.801 1.00 85.49  ? 197 GLU B OE2 1 
ATOM   4590 N N   . LEU B 1 198 ? 97.826  150.756 145.461 1.00 69.08  ? 198 LEU B N   1 
ATOM   4591 C CA  . LEU B 1 198 ? 96.601  150.514 146.210 1.00 69.28  ? 198 LEU B CA  1 
ATOM   4592 C C   . LEU B 1 198 ? 96.692  149.247 147.048 1.00 71.41  ? 198 LEU B C   1 
ATOM   4593 O O   . LEU B 1 198 ? 96.052  149.159 148.100 1.00 73.77  ? 198 LEU B O   1 
ATOM   4594 C CB  . LEU B 1 198 ? 95.410  150.437 145.259 1.00 68.03  ? 198 LEU B CB  1 
ATOM   4595 C CG  . LEU B 1 198 ? 95.165  151.711 144.455 1.00 68.51  ? 198 LEU B CG  1 
ATOM   4596 C CD1 . LEU B 1 198 ? 93.972  151.545 143.539 1.00 69.67  ? 198 LEU B CD1 1 
ATOM   4597 C CD2 . LEU B 1 198 ? 94.965  152.882 145.390 1.00 71.25  ? 198 LEU B CD2 1 
ATOM   4598 N N   . THR B 1 199 ? 97.471  148.258 146.602 1.00 67.81  ? 199 THR B N   1 
ATOM   4599 C CA  . THR B 1 199 ? 97.698  147.066 147.412 1.00 66.29  ? 199 THR B CA  1 
ATOM   4600 C C   . THR B 1 199 ? 98.690  147.330 148.536 1.00 69.66  ? 199 THR B C   1 
ATOM   4601 O O   . THR B 1 199 ? 98.550  146.768 149.626 1.00 77.30  ? 199 THR B O   1 
ATOM   4602 C CB  . THR B 1 199 ? 98.182  145.914 146.532 1.00 68.18  ? 199 THR B CB  1 
ATOM   4603 O OG1 . THR B 1 199 ? 97.209  145.648 145.517 1.00 74.89  ? 199 THR B OG1 1 
ATOM   4604 C CG2 . THR B 1 199 ? 98.380  144.659 147.352 1.00 69.00  ? 199 THR B CG2 1 
ATOM   4605 N N   . GLU B 1 200 ? 99.692  148.177 148.296 1.00 78.26  ? 200 GLU B N   1 
ATOM   4606 C CA  . GLU B 1 200 ? 100.560 148.615 149.384 1.00 77.47  ? 200 GLU B CA  1 
ATOM   4607 C C   . GLU B 1 200 ? 99.795  149.473 150.378 1.00 75.45  ? 200 GLU B C   1 
ATOM   4608 O O   . GLU B 1 200 ? 100.065 149.430 151.582 1.00 76.33  ? 200 GLU B O   1 
ATOM   4609 C CB  . GLU B 1 200 ? 101.753 149.389 148.830 1.00 78.37  ? 200 GLU B CB  1 
ATOM   4610 C CG  . GLU B 1 200 ? 102.999 149.315 149.688 1.00 75.60  ? 200 GLU B CG  1 
ATOM   4611 C CD  . GLU B 1 200 ? 104.180 150.011 149.047 1.00 84.88  ? 200 GLU B CD  1 
ATOM   4612 O OE1 . GLU B 1 200 ? 104.021 151.166 148.606 1.00 82.61  ? 200 GLU B OE1 1 
ATOM   4613 O OE2 . GLU B 1 200 ? 105.268 149.405 148.983 1.00 89.86  ? 200 GLU B OE2 1 
ATOM   4614 N N   . LEU B 1 201 ? 98.846  150.270 149.889 1.00 79.77  ? 201 LEU B N   1 
ATOM   4615 C CA  . LEU B 1 201 ? 98.045  151.094 150.785 1.00 80.46  ? 201 LEU B CA  1 
ATOM   4616 C C   . LEU B 1 201 ? 97.017  150.261 151.536 1.00 80.21  ? 201 LEU B C   1 
ATOM   4617 O O   . LEU B 1 201 ? 96.757  150.510 152.716 1.00 81.50  ? 201 LEU B O   1 
ATOM   4618 C CB  . LEU B 1 201 ? 97.359  152.209 150.002 1.00 80.65  ? 201 LEU B CB  1 
ATOM   4619 C CG  . LEU B 1 201 ? 96.460  153.128 150.825 1.00 81.36  ? 201 LEU B CG  1 
ATOM   4620 C CD1 . LEU B 1 201 ? 97.282  153.883 151.852 1.00 82.49  ? 201 LEU B CD1 1 
ATOM   4621 C CD2 . LEU B 1 201 ? 95.710  154.086 149.919 1.00 85.02  ? 201 LEU B CD2 1 
ATOM   4622 N N   . PHE B 1 202 ? 96.416  149.270 150.872 1.00 74.63  ? 202 PHE B N   1 
ATOM   4623 C CA  . PHE B 1 202 ? 95.404  148.456 151.538 1.00 76.19  ? 202 PHE B CA  1 
ATOM   4624 C C   . PHE B 1 202 ? 95.985  147.677 152.705 1.00 83.46  ? 202 PHE B C   1 
ATOM   4625 O O   . PHE B 1 202 ? 95.268  147.368 153.662 1.00 89.06  ? 202 PHE B O   1 
ATOM   4626 C CB  . PHE B 1 202 ? 94.758  147.489 150.552 1.00 76.47  ? 202 PHE B CB  1 
ATOM   4627 C CG  . PHE B 1 202 ? 93.895  146.451 151.207 1.00 78.90  ? 202 PHE B CG  1 
ATOM   4628 C CD1 . PHE B 1 202 ? 92.657  146.787 151.720 1.00 78.55  ? 202 PHE B CD1 1 
ATOM   4629 C CD2 . PHE B 1 202 ? 94.324  145.142 151.317 1.00 78.92  ? 202 PHE B CD2 1 
ATOM   4630 C CE1 . PHE B 1 202 ? 91.862  145.835 152.321 1.00 79.68  ? 202 PHE B CE1 1 
ATOM   4631 C CE2 . PHE B 1 202 ? 93.534  144.188 151.920 1.00 78.28  ? 202 PHE B CE2 1 
ATOM   4632 C CZ  . PHE B 1 202 ? 92.301  144.535 152.421 1.00 79.87  ? 202 PHE B CZ  1 
ATOM   4633 N N   . PHE B 1 203 ? 97.276  147.362 152.656 1.00 83.99  ? 203 PHE B N   1 
ATOM   4634 C CA  . PHE B 1 203 ? 97.932  146.583 153.696 1.00 80.00  ? 203 PHE B CA  1 
ATOM   4635 C C   . PHE B 1 203 ? 98.297  147.424 154.909 1.00 76.14  ? 203 PHE B C   1 
ATOM   4636 O O   . PHE B 1 203 ? 99.170  147.027 155.688 1.00 78.98  ? 203 PHE B O   1 
ATOM   4637 C CB  . PHE B 1 203 ? 99.169  145.890 153.122 1.00 74.21  ? 203 PHE B CB  1 
ATOM   4638 C CG  . PHE B 1 203 ? 98.858  144.636 152.351 1.00 73.31  ? 203 PHE B CG  1 
ATOM   4639 C CD1 . PHE B 1 203 ? 97.570  144.365 151.936 1.00 72.98  ? 203 PHE B CD1 1 
ATOM   4640 C CD2 . PHE B 1 203 ? 99.856  143.746 152.011 1.00 74.61  ? 203 PHE B CD2 1 
ATOM   4641 C CE1 . PHE B 1 203 ? 97.283  143.224 151.223 1.00 74.24  ? 203 PHE B CE1 1 
ATOM   4642 C CE2 . PHE B 1 203 ? 99.571  142.607 151.294 1.00 72.89  ? 203 PHE B CE2 1 
ATOM   4643 C CZ  . PHE B 1 203 ? 98.285  142.347 150.900 1.00 73.33  ? 203 PHE B CZ  1 
ATOM   4644 N N   . MET B 1 204 ? 97.657  148.586 155.065 1.00 83.46  ? 204 MET B N   1 
ATOM   4645 C CA  . MET B 1 204 ? 97.846  149.399 156.262 1.00 89.72  ? 204 MET B CA  1 
ATOM   4646 C C   . MET B 1 204 ? 97.424  148.656 157.519 1.00 97.26  ? 204 MET B C   1 
ATOM   4647 O O   . MET B 1 204 ? 98.011  148.862 158.587 1.00 99.24  ? 204 MET B O   1 
ATOM   4648 C CB  . MET B 1 204 ? 97.054  150.699 156.140 1.00 91.21  ? 204 MET B CB  1 
ATOM   4649 C CG  . MET B 1 204 ? 95.654  150.518 155.567 1.00 90.14  ? 204 MET B CG  1 
ATOM   4650 S SD  . MET B 1 204 ? 94.421  149.946 156.747 1.00 97.96  ? 204 MET B SD  1 
ATOM   4651 C CE  . MET B 1 204 ? 94.181  151.429 157.720 1.00 92.07  ? 204 MET B CE  1 
ATOM   4652 N N   . HIS B 1 205 ? 96.406  147.799 157.419 1.00 96.40  ? 205 HIS B N   1 
ATOM   4653 C CA  . HIS B 1 205 ? 95.925  147.080 158.593 1.00 99.35  ? 205 HIS B CA  1 
ATOM   4654 C C   . HIS B 1 205 ? 96.989  146.156 159.170 1.00 99.63  ? 205 HIS B C   1 
ATOM   4655 O O   . HIS B 1 205 ? 96.999  145.901 160.379 1.00 96.87  ? 205 HIS B O   1 
ATOM   4656 C CB  . HIS B 1 205 ? 94.665  146.294 158.238 1.00 92.45  ? 205 HIS B CB  1 
ATOM   4657 C CG  . HIS B 1 205 ? 94.875  145.267 157.171 1.00 92.39  ? 205 HIS B CG  1 
ATOM   4658 N ND1 . HIS B 1 205 ? 95.578  144.102 157.384 1.00 94.37  ? 205 HIS B ND1 1 
ATOM   4659 C CD2 . HIS B 1 205 ? 94.475  145.234 155.879 1.00 96.95  ? 205 HIS B CD2 1 
ATOM   4660 C CE1 . HIS B 1 205 ? 95.601  143.394 156.269 1.00 97.43  ? 205 HIS B CE1 1 
ATOM   4661 N NE2 . HIS B 1 205 ? 94.939  144.059 155.341 1.00 97.55  ? 205 HIS B NE2 1 
ATOM   4662 N N   . LEU B 1 206 ? 97.886  145.639 158.327 1.00 98.59  ? 206 LEU B N   1 
ATOM   4663 C CA  . LEU B 1 206 ? 98.957  144.784 158.827 1.00 96.04  ? 206 LEU B CA  1 
ATOM   4664 C C   . LEU B 1 206 ? 99.904  145.562 159.730 1.00 99.82  ? 206 LEU B C   1 
ATOM   4665 O O   . LEU B 1 206 ? 100.327 145.057 160.776 1.00 103.50 ? 206 LEU B O   1 
ATOM   4666 C CB  . LEU B 1 206 ? 99.720  144.158 157.660 1.00 95.33  ? 206 LEU B CB  1 
ATOM   4667 C CG  . LEU B 1 206 ? 99.022  142.996 156.945 1.00 102.78 ? 206 LEU B CG  1 
ATOM   4668 C CD1 . LEU B 1 206 ? 99.985  142.278 156.026 1.00 101.63 ? 206 LEU B CD1 1 
ATOM   4669 C CD2 . LEU B 1 206 ? 98.402  142.019 157.931 1.00 102.48 ? 206 LEU B CD2 1 
ATOM   4670 N N   . LEU B 1 207 ? 100.240 146.793 159.351 1.00 117.45 ? 207 LEU B N   1 
ATOM   4671 C CA  . LEU B 1 207 ? 101.163 147.639 160.109 1.00 120.33 ? 207 LEU B CA  1 
ATOM   4672 C C   . LEU B 1 207 ? 100.505 148.997 160.322 1.00 119.70 ? 207 LEU B C   1 
ATOM   4673 O O   . LEU B 1 207 ? 100.857 149.986 159.663 1.00 116.65 ? 207 LEU B O   1 
ATOM   4674 C CB  . LEU B 1 207 ? 102.507 147.762 159.388 1.00 117.81 ? 207 LEU B CB  1 
ATOM   4675 C CG  . LEU B 1 207 ? 103.629 148.573 160.038 1.00 118.18 ? 207 LEU B CG  1 
ATOM   4676 C CD1 . LEU B 1 207 ? 104.853 147.699 160.253 1.00 116.99 ? 207 LEU B CD1 1 
ATOM   4677 C CD2 . LEU B 1 207 ? 103.982 149.781 159.185 1.00 118.99 ? 207 LEU B CD2 1 
ATOM   4678 N N   . PRO B 1 208 ? 99.529  149.081 161.229 1.00 128.47 ? 208 PRO B N   1 
ATOM   4679 C CA  . PRO B 1 208 ? 98.859  150.360 161.484 1.00 128.80 ? 208 PRO B CA  1 
ATOM   4680 C C   . PRO B 1 208 ? 99.579  151.251 162.481 1.00 129.69 ? 208 PRO B C   1 
ATOM   4681 O O   . PRO B 1 208 ? 99.117  152.371 162.726 1.00 129.75 ? 208 PRO B O   1 
ATOM   4682 C CB  . PRO B 1 208 ? 97.497  149.919 162.032 1.00 126.98 ? 208 PRO B CB  1 
ATOM   4683 C CG  . PRO B 1 208 ? 97.801  148.649 162.754 1.00 126.19 ? 208 PRO B CG  1 
ATOM   4684 C CD  . PRO B 1 208 ? 98.938  147.983 162.015 1.00 124.48 ? 208 PRO B CD  1 
ATOM   4685 N N   . ASN B 1 209 ? 100.684 150.784 163.066 1.00 138.00 ? 209 ASN B N   1 
ATOM   4686 C CA  . ASN B 1 209 ? 101.384 151.573 164.075 1.00 137.55 ? 209 ASN B CA  1 
ATOM   4687 C C   . ASN B 1 209 ? 101.975 152.847 163.483 1.00 138.32 ? 209 ASN B C   1 
ATOM   4688 O O   . ASN B 1 209 ? 101.919 153.912 164.109 1.00 135.80 ? 209 ASN B O   1 
ATOM   4689 C CB  . ASN B 1 209 ? 102.473 150.727 164.732 1.00 137.03 ? 209 ASN B CB  1 
ATOM   4690 C CG  . ASN B 1 209 ? 103.255 149.902 163.729 1.00 137.59 ? 209 ASN B CG  1 
ATOM   4691 O OD1 . ASN B 1 209 ? 102.748 148.917 163.190 1.00 135.86 ? 209 ASN B OD1 1 
ATOM   4692 N ND2 . ASN B 1 209 ? 104.498 150.295 163.478 1.00 136.64 ? 209 ASN B ND2 1 
ATOM   4693 N N   . PHE B 1 210 ? 102.548 152.759 162.285 1.00 145.58 ? 210 PHE B N   1 
ATOM   4694 C CA  . PHE B 1 210 ? 103.186 153.917 161.675 1.00 145.96 ? 210 PHE B CA  1 
ATOM   4695 C C   . PHE B 1 210 ? 102.147 154.962 161.285 1.00 144.83 ? 210 PHE B C   1 
ATOM   4696 O O   . PHE B 1 210 ? 101.070 154.635 160.778 1.00 144.40 ? 210 PHE B O   1 
ATOM   4697 C CB  . PHE B 1 210 ? 103.996 153.491 160.450 1.00 144.77 ? 210 PHE B CB  1 
ATOM   4698 C CG  . PHE B 1 210 ? 104.499 154.640 159.622 1.00 144.63 ? 210 PHE B CG  1 
ATOM   4699 C CD1 . PHE B 1 210 ? 105.282 155.631 160.190 1.00 144.55 ? 210 PHE B CD1 1 
ATOM   4700 C CD2 . PHE B 1 210 ? 104.200 154.722 158.273 1.00 144.28 ? 210 PHE B CD2 1 
ATOM   4701 C CE1 . PHE B 1 210 ? 105.749 156.688 159.430 1.00 144.02 ? 210 PHE B CE1 1 
ATOM   4702 C CE2 . PHE B 1 210 ? 104.667 155.775 157.509 1.00 145.58 ? 210 PHE B CE2 1 
ATOM   4703 C CZ  . PHE B 1 210 ? 105.440 156.760 158.088 1.00 145.08 ? 210 PHE B CZ  1 
ATOM   4704 N N   . ALA B 1 211 ? 102.476 156.228 161.529 1.00 145.30 ? 211 ALA B N   1 
ATOM   4705 C CA  . ALA B 1 211 ? 101.594 157.343 161.204 1.00 145.14 ? 211 ALA B CA  1 
ATOM   4706 C C   . ALA B 1 211 ? 101.770 157.692 159.731 1.00 146.54 ? 211 ALA B C   1 
ATOM   4707 O O   . ALA B 1 211 ? 102.829 158.179 159.322 1.00 146.30 ? 211 ALA B O   1 
ATOM   4708 C CB  . ALA B 1 211 ? 101.893 158.546 162.095 1.00 145.38 ? 211 ALA B CB  1 
ATOM   4709 N N   . GLU B 1 212 ? 100.732 157.445 158.936 1.00 148.90 ? 212 GLU B N   1 
ATOM   4710 C CA  . GLU B 1 212 ? 100.771 157.737 157.512 1.00 148.23 ? 212 GLU B CA  1 
ATOM   4711 C C   . GLU B 1 212 ? 99.359  158.018 157.024 1.00 148.23 ? 212 GLU B C   1 
ATOM   4712 O O   . GLU B 1 212 ? 98.372  157.660 157.672 1.00 148.86 ? 212 GLU B O   1 
ATOM   4713 C CB  . GLU B 1 212 ? 101.395 156.586 156.712 1.00 146.53 ? 212 GLU B CB  1 
ATOM   4714 C CG  . GLU B 1 212 ? 100.865 155.207 157.080 1.00 145.94 ? 212 GLU B CG  1 
ATOM   4715 C CD  . GLU B 1 212 ? 99.611  154.836 156.315 1.00 146.72 ? 212 GLU B CD  1 
ATOM   4716 O OE1 . GLU B 1 212 ? 99.643  154.861 155.066 1.00 146.73 ? 212 GLU B OE1 1 
ATOM   4717 O OE2 . GLU B 1 212 ? 98.591  154.519 156.962 1.00 146.30 ? 212 GLU B OE2 1 
ATOM   4718 N N   . CYS B 1 213 ? 99.278  158.664 155.867 1.00 139.30 ? 213 CYS B N   1 
ATOM   4719 C CA  . CYS B 1 213 ? 98.012  158.986 155.232 1.00 139.15 ? 213 CYS B CA  1 
ATOM   4720 C C   . CYS B 1 213 ? 97.965  158.362 153.844 1.00 138.33 ? 213 CYS B C   1 
ATOM   4721 O O   . CYS B 1 213 ? 98.976  157.904 153.306 1.00 136.15 ? 213 CYS B O   1 
ATOM   4722 C CB  . CYS B 1 213 ? 97.808  160.504 155.149 1.00 137.46 ? 213 CYS B CB  1 
ATOM   4723 S SG  . CYS B 1 213 ? 96.092  161.014 154.913 1.00 139.76 ? 213 CYS B SG  1 
ATOM   4724 N N   . TRP B 1 214 ? 96.762  158.340 153.269 1.00 132.94 ? 214 TRP B N   1 
ATOM   4725 C CA  . TRP B 1 214 ? 96.602  157.806 151.922 1.00 130.81 ? 214 TRP B CA  1 
ATOM   4726 C C   . TRP B 1 214 ? 97.364  158.636 150.899 1.00 131.51 ? 214 TRP B C   1 
ATOM   4727 O O   . TRP B 1 214 ? 97.855  158.094 149.903 1.00 131.48 ? 214 TRP B O   1 
ATOM   4728 C CB  . TRP B 1 214 ? 95.120  157.740 151.557 1.00 130.27 ? 214 TRP B CB  1 
ATOM   4729 C CG  . TRP B 1 214 ? 94.298  158.790 152.230 1.00 133.02 ? 214 TRP B CG  1 
ATOM   4730 C CD1 . TRP B 1 214 ? 93.605  158.665 153.399 1.00 133.14 ? 214 TRP B CD1 1 
ATOM   4731 C CD2 . TRP B 1 214 ? 94.073  160.129 151.772 1.00 133.96 ? 214 TRP B CD2 1 
ATOM   4732 N NE1 . TRP B 1 214 ? 92.967  159.844 153.700 1.00 133.99 ? 214 TRP B NE1 1 
ATOM   4733 C CE2 . TRP B 1 214 ? 93.237  160.759 152.716 1.00 134.78 ? 214 TRP B CE2 1 
ATOM   4734 C CE3 . TRP B 1 214 ? 94.497  160.857 150.656 1.00 130.62 ? 214 TRP B CE3 1 
ATOM   4735 C CZ2 . TRP B 1 214 ? 92.818  162.080 152.578 1.00 132.21 ? 214 TRP B CZ2 1 
ATOM   4736 C CZ3 . TRP B 1 214 ? 94.081  162.168 150.522 1.00 131.02 ? 214 TRP B CZ3 1 
ATOM   4737 C CH2 . TRP B 1 214 ? 93.250  162.766 151.477 1.00 131.88 ? 214 TRP B CH2 1 
ATOM   4738 N N   . TRP B 1 215 ? 97.485  159.943 151.129 1.00 136.16 ? 215 TRP B N   1 
ATOM   4739 C CA  . TRP B 1 215 ? 98.166  160.821 150.189 1.00 135.37 ? 215 TRP B CA  1 
ATOM   4740 C C   . TRP B 1 215 ? 99.672  160.598 150.158 1.00 134.63 ? 215 TRP B C   1 
ATOM   4741 O O   . TRP B 1 215 ? 100.342 161.136 149.269 1.00 134.10 ? 215 TRP B O   1 
ATOM   4742 C CB  . TRP B 1 215 ? 97.860  162.283 150.523 1.00 135.09 ? 215 TRP B CB  1 
ATOM   4743 C CG  . TRP B 1 215 ? 98.848  162.918 151.441 1.00 138.62 ? 215 TRP B CG  1 
ATOM   4744 C CD1 . TRP B 1 215 ? 98.942  162.744 152.788 1.00 138.89 ? 215 TRP B CD1 1 
ATOM   4745 C CD2 . TRP B 1 215 ? 99.870  163.855 151.083 1.00 140.12 ? 215 TRP B CD2 1 
ATOM   4746 N NE1 . TRP B 1 215 ? 99.971  163.502 153.292 1.00 141.10 ? 215 TRP B NE1 1 
ATOM   4747 C CE2 . TRP B 1 215 ? 100.556 164.195 152.266 1.00 140.20 ? 215 TRP B CE2 1 
ATOM   4748 C CE3 . TRP B 1 215 ? 100.276 164.435 149.878 1.00 136.85 ? 215 TRP B CE3 1 
ATOM   4749 C CZ2 . TRP B 1 215 ? 101.623 165.089 152.278 1.00 137.20 ? 215 TRP B CZ2 1 
ATOM   4750 C CZ3 . TRP B 1 215 ? 101.337 165.323 149.893 1.00 137.41 ? 215 TRP B CZ3 1 
ATOM   4751 C CH2 . TRP B 1 215 ? 101.998 165.641 151.085 1.00 137.72 ? 215 TRP B CH2 1 
ATOM   4752 N N   . ASP B 1 216 ? 100.220 159.835 151.104 1.00 125.44 ? 216 ASP B N   1 
ATOM   4753 C CA  . ASP B 1 216 ? 101.624 159.447 151.020 1.00 126.67 ? 216 ASP B CA  1 
ATOM   4754 C C   . ASP B 1 216 ? 101.863 158.546 149.815 1.00 128.33 ? 216 ASP B C   1 
ATOM   4755 O O   . ASP B 1 216 ? 102.867 158.684 149.108 1.00 127.52 ? 216 ASP B O   1 
ATOM   4756 C CB  . ASP B 1 216 ? 102.047 158.747 152.312 1.00 130.92 ? 216 ASP B CB  1 
ATOM   4757 C CG  . ASP B 1 216 ? 103.448 158.162 152.236 1.00 130.51 ? 216 ASP B CG  1 
ATOM   4758 O OD1 . ASP B 1 216 ? 104.280 158.682 151.464 1.00 127.84 ? 216 ASP B OD1 1 
ATOM   4759 O OD2 . ASP B 1 216 ? 103.715 157.172 152.951 1.00 129.26 ? 216 ASP B OD2 1 
ATOM   4760 N N   . GLN B 1 217 ? 100.944 157.614 149.564 1.00 118.51 ? 217 GLN B N   1 
ATOM   4761 C CA  . GLN B 1 217 ? 101.056 156.673 148.458 1.00 112.83 ? 217 GLN B CA  1 
ATOM   4762 C C   . GLN B 1 217 ? 100.046 156.961 147.354 1.00 113.41 ? 217 GLN B C   1 
ATOM   4763 O O   . GLN B 1 217 ? 99.609  156.041 146.657 1.00 114.93 ? 217 GLN B O   1 
ATOM   4764 C CB  . GLN B 1 217 ? 100.896 155.240 148.963 1.00 112.54 ? 217 GLN B CB  1 
ATOM   4765 C CG  . GLN B 1 217 ? 101.876 154.858 150.061 1.00 115.13 ? 217 GLN B CG  1 
ATOM   4766 C CD  . GLN B 1 217 ? 103.202 154.366 149.518 1.00 116.12 ? 217 GLN B CD  1 
ATOM   4767 O OE1 . GLN B 1 217 ? 104.237 155.005 149.705 1.00 115.93 ? 217 GLN B OE1 1 
ATOM   4768 N NE2 . GLN B 1 217 ? 103.178 153.228 148.838 1.00 113.46 ? 217 GLN B NE2 1 
ATOM   4769 N N   . VAL B 1 218 ? 99.655  158.225 147.192 1.00 117.38 ? 218 VAL B N   1 
ATOM   4770 C CA  . VAL B 1 218 ? 98.733  158.649 146.145 1.00 118.06 ? 218 VAL B CA  1 
ATOM   4771 C C   . VAL B 1 218 ? 99.343  159.742 145.277 1.00 115.90 ? 218 VAL B C   1 
ATOM   4772 O O   . VAL B 1 218 ? 99.252  159.699 144.046 1.00 113.64 ? 218 VAL B O   1 
ATOM   4773 C CB  . VAL B 1 218 ? 97.382  159.107 146.737 1.00 116.63 ? 218 VAL B CB  1 
ATOM   4774 C CG1 . VAL B 1 218 ? 96.700  160.108 145.818 1.00 113.89 ? 218 VAL B CG1 1 
ATOM   4775 C CG2 . VAL B 1 218 ? 96.483  157.903 146.974 1.00 115.05 ? 218 VAL B CG2 1 
ATOM   4776 N N   . ILE B 1 219 ? 99.971  160.733 145.901 1.00 121.39 ? 219 ILE B N   1 
ATOM   4777 C CA  . ILE B 1 219 ? 100.631 161.801 145.160 1.00 120.96 ? 219 ILE B CA  1 
ATOM   4778 C C   . ILE B 1 219 ? 102.133 161.575 145.084 1.00 119.13 ? 219 ILE B C   1 
ATOM   4779 O O   . ILE B 1 219 ? 102.736 161.695 144.015 1.00 119.41 ? 219 ILE B O   1 
ATOM   4780 C CB  . ILE B 1 219 ? 100.301 163.168 145.795 1.00 123.77 ? 219 ILE B CB  1 
ATOM   4781 C CG1 . ILE B 1 219 ? 98.797  163.440 145.721 1.00 123.14 ? 219 ILE B CG1 1 
ATOM   4782 C CG2 . ILE B 1 219 ? 101.086 164.277 145.115 1.00 119.53 ? 219 ILE B CG2 1 
ATOM   4783 C CD1 . ILE B 1 219 ? 98.392  164.787 146.275 1.00 120.38 ? 219 ILE B CD1 1 
ATOM   4784 N N   . LEU B 1 220 ? 102.759 161.239 146.214 1.00 116.51 ? 220 LEU B N   1 
ATOM   4785 C CA  . LEU B 1 220 ? 104.211 161.106 146.241 1.00 119.04 ? 220 LEU B CA  1 
ATOM   4786 C C   . LEU B 1 220 ? 104.693 159.957 145.364 1.00 119.04 ? 220 LEU B C   1 
ATOM   4787 O O   . LEU B 1 220 ? 105.777 160.043 144.778 1.00 120.05 ? 220 LEU B O   1 
ATOM   4788 C CB  . LEU B 1 220 ? 104.697 160.918 147.681 1.00 120.57 ? 220 LEU B CB  1 
ATOM   4789 C CG  . LEU B 1 220 ? 106.174 160.581 147.916 1.00 118.61 ? 220 LEU B CG  1 
ATOM   4790 C CD1 . LEU B 1 220 ? 106.999 161.848 147.992 1.00 117.79 ? 220 LEU B CD1 1 
ATOM   4791 C CD2 . LEU B 1 220 ? 106.365 159.752 149.174 1.00 116.00 ? 220 LEU B CD2 1 
ATOM   4792 N N   . ASP B 1 221 ? 103.909 158.885 145.249 1.00 105.80 ? 221 ASP B N   1 
ATOM   4793 C CA  . ASP B 1 221 ? 104.341 157.700 144.515 1.00 104.02 ? 221 ASP B CA  1 
ATOM   4794 C C   . ASP B 1 221 ? 103.635 157.548 143.171 1.00 103.64 ? 221 ASP B C   1 
ATOM   4795 O O   . ASP B 1 221 ? 104.297 157.457 142.134 1.00 108.24 ? 221 ASP B O   1 
ATOM   4796 C CB  . ASP B 1 221 ? 104.133 156.449 145.374 1.00 104.17 ? 221 ASP B CB  1 
ATOM   4797 C CG  . ASP B 1 221 ? 105.253 156.242 146.368 1.00 106.19 ? 221 ASP B CG  1 
ATOM   4798 O OD1 . ASP B 1 221 ? 106.108 157.143 146.487 1.00 104.31 ? 221 ASP B OD1 1 
ATOM   4799 O OD2 . ASP B 1 221 ? 105.282 155.181 147.025 1.00 108.90 ? 221 ASP B OD2 1 
ATOM   4800 N N   . ILE B 1 222 ? 102.301 157.526 143.166 1.00 97.01  ? 222 ILE B N   1 
ATOM   4801 C CA  . ILE B 1 222 ? 101.576 157.238 141.930 1.00 101.91 ? 222 ILE B CA  1 
ATOM   4802 C C   . ILE B 1 222 ? 101.847 158.309 140.882 1.00 101.85 ? 222 ILE B C   1 
ATOM   4803 O O   . ILE B 1 222 ? 102.021 158.005 139.696 1.00 100.53 ? 222 ILE B O   1 
ATOM   4804 C CB  . ILE B 1 222 ? 100.070 157.086 142.206 1.00 100.49 ? 222 ILE B CB  1 
ATOM   4805 C CG1 . ILE B 1 222 ? 99.836  156.128 143.371 1.00 99.85  ? 222 ILE B CG1 1 
ATOM   4806 C CG2 . ILE B 1 222 ? 99.354  156.581 140.970 1.00 97.73  ? 222 ILE B CG2 1 
ATOM   4807 C CD1 . ILE B 1 222 ? 98.379  155.815 143.613 1.00 97.94  ? 222 ILE B CD1 1 
ATOM   4808 N N   . LEU B 1 223 ? 101.890 159.573 141.295 1.00 102.86 ? 223 LEU B N   1 
ATOM   4809 C CA  . LEU B 1 223 ? 102.052 160.664 140.343 1.00 100.94 ? 223 LEU B CA  1 
ATOM   4810 C C   . LEU B 1 223 ? 103.514 161.032 140.111 1.00 100.71 ? 223 LEU B C   1 
ATOM   4811 O O   . LEU B 1 223 ? 103.948 161.151 138.963 1.00 104.24 ? 223 LEU B O   1 
ATOM   4812 C CB  . LEU B 1 223 ? 101.276 161.894 140.818 1.00 100.69 ? 223 LEU B CB  1 
ATOM   4813 C CG  . LEU B 1 223 ? 99.763  161.728 140.926 1.00 102.38 ? 223 LEU B CG  1 
ATOM   4814 C CD1 . LEU B 1 223 ? 99.099  163.072 141.157 1.00 102.67 ? 223 LEU B CD1 1 
ATOM   4815 C CD2 . LEU B 1 223 ? 99.212  161.062 139.680 1.00 100.21 ? 223 LEU B CD2 1 
ATOM   4816 N N   . LEU B 1 224 ? 104.287 161.217 141.179 1.00 98.87  ? 224 LEU B N   1 
ATOM   4817 C CA  . LEU B 1 224 ? 105.630 161.771 141.034 1.00 99.25  ? 224 LEU B CA  1 
ATOM   4818 C C   . LEU B 1 224 ? 106.698 160.686 140.905 1.00 98.63  ? 224 LEU B C   1 
ATOM   4819 O O   . LEU B 1 224 ? 107.410 160.631 139.899 1.00 101.27 ? 224 LEU B O   1 
ATOM   4820 C CB  . LEU B 1 224 ? 105.941 162.696 142.215 1.00 101.42 ? 224 LEU B CB  1 
ATOM   4821 C CG  . LEU B 1 224 ? 104.962 163.855 142.407 1.00 104.61 ? 224 LEU B CG  1 
ATOM   4822 C CD1 . LEU B 1 224 ? 105.519 164.870 143.390 1.00 104.44 ? 224 LEU B CD1 1 
ATOM   4823 C CD2 . LEU B 1 224 ? 104.639 164.513 141.078 1.00 101.80 ? 224 LEU B CD2 1 
ATOM   4824 N N   . CYS B 1 225 ? 106.823 159.822 141.912 1.00 97.48  ? 225 CYS B N   1 
ATOM   4825 C CA  . CYS B 1 225 ? 107.879 158.814 141.890 1.00 97.98  ? 225 CYS B CA  1 
ATOM   4826 C C   . CYS B 1 225 ? 107.674 157.826 140.747 1.00 99.12  ? 225 CYS B C   1 
ATOM   4827 O O   . CYS B 1 225 ? 108.527 157.690 139.865 1.00 102.95 ? 225 CYS B O   1 
ATOM   4828 C CB  . CYS B 1 225 ? 107.938 158.082 143.232 1.00 100.19 ? 225 CYS B CB  1 
ATOM   4829 S SG  . CYS B 1 225 ? 108.727 159.004 144.568 1.00 106.87 ? 225 CYS B SG  1 
ATOM   4830 N N   . ASN B 1 226 ? 106.545 157.117 140.751 1.00 93.50  ? 226 ASN B N   1 
ATOM   4831 C CA  . ASN B 1 226 ? 106.291 156.140 139.699 1.00 88.03  ? 226 ASN B CA  1 
ATOM   4832 C C   . ASN B 1 226 ? 105.953 156.824 138.381 1.00 92.51  ? 226 ASN B C   1 
ATOM   4833 O O   . ASN B 1 226 ? 106.469 156.445 137.324 1.00 95.04  ? 226 ASN B O   1 
ATOM   4834 C CB  . ASN B 1 226 ? 105.166 155.196 140.118 1.00 90.17  ? 226 ASN B CB  1 
ATOM   4835 C CG  . ASN B 1 226 ? 105.296 154.735 141.554 1.00 94.18  ? 226 ASN B CG  1 
ATOM   4836 O OD1 . ASN B 1 226 ? 106.337 154.909 142.182 1.00 95.70  ? 226 ASN B OD1 1 
ATOM   4837 N ND2 . ASN B 1 226 ? 104.235 154.140 142.080 1.00 91.25  ? 226 ASN B ND2 1 
ATOM   4838 N N   . GLY B 1 227 ? 105.085 157.836 138.425 1.00 94.03  ? 227 GLY B N   1 
ATOM   4839 C CA  . GLY B 1 227 ? 104.681 158.505 137.199 1.00 93.54  ? 227 GLY B CA  1 
ATOM   4840 C C   . GLY B 1 227 ? 105.824 159.237 136.524 1.00 89.92  ? 227 GLY B C   1 
ATOM   4841 O O   . GLY B 1 227 ? 105.956 159.206 135.299 1.00 92.04  ? 227 GLY B O   1 
ATOM   4842 N N   . GLY B 1 228 ? 106.659 159.916 137.310 1.00 74.48  ? 228 GLY B N   1 
ATOM   4843 C CA  . GLY B 1 228 ? 107.828 160.559 136.740 1.00 77.26  ? 228 GLY B CA  1 
ATOM   4844 C C   . GLY B 1 228 ? 108.841 159.561 136.216 1.00 76.38  ? 228 GLY B C   1 
ATOM   4845 O O   . GLY B 1 228 ? 109.488 159.799 135.195 1.00 82.36  ? 228 GLY B O   1 
ATOM   4846 N N   . GLY B 1 229 ? 108.999 158.436 136.912 1.00 77.31  ? 229 GLY B N   1 
ATOM   4847 C CA  . GLY B 1 229 ? 109.950 157.433 136.466 1.00 76.67  ? 229 GLY B CA  1 
ATOM   4848 C C   . GLY B 1 229 ? 109.565 156.811 135.141 1.00 81.20  ? 229 GLY B C   1 
ATOM   4849 O O   . GLY B 1 229 ? 110.419 156.585 134.282 1.00 90.06  ? 229 GLY B O   1 
ATOM   4850 N N   . ILE B 1 230 ? 108.277 156.522 134.958 1.00 77.97  ? 230 ILE B N   1 
ATOM   4851 C CA  . ILE B 1 230 ? 107.821 155.931 133.705 1.00 77.33  ? 230 ILE B CA  1 
ATOM   4852 C C   . ILE B 1 230 ? 108.053 156.892 132.547 1.00 77.69  ? 230 ILE B C   1 
ATOM   4853 O O   . ILE B 1 230 ? 108.512 156.491 131.472 1.00 77.89  ? 230 ILE B O   1 
ATOM   4854 C CB  . ILE B 1 230 ? 106.342 155.525 133.818 1.00 72.78  ? 230 ILE B CB  1 
ATOM   4855 C CG1 . ILE B 1 230 ? 106.175 154.433 134.867 1.00 69.58  ? 230 ILE B CG1 1 
ATOM   4856 C CG2 . ILE B 1 230 ? 105.823 155.039 132.489 1.00 75.72  ? 230 ILE B CG2 1 
ATOM   4857 C CD1 . ILE B 1 230 ? 104.742 154.081 135.128 1.00 74.98  ? 230 ILE B CD1 1 
ATOM   4858 N N   . TRP B 1 231 ? 107.750 158.175 132.751 1.00 71.89  ? 231 TRP B N   1 
ATOM   4859 C CA  . TRP B 1 231 ? 107.930 159.159 131.689 1.00 71.01  ? 231 TRP B CA  1 
ATOM   4860 C C   . TRP B 1 231 ? 109.387 159.240 131.256 1.00 73.75  ? 231 TRP B C   1 
ATOM   4861 O O   . TRP B 1 231 ? 109.692 159.232 130.059 1.00 82.29  ? 231 TRP B O   1 
ATOM   4862 C CB  . TRP B 1 231 ? 107.432 160.525 132.155 1.00 70.42  ? 231 TRP B CB  1 
ATOM   4863 C CG  . TRP B 1 231 ? 107.199 161.499 131.047 1.00 72.54  ? 231 TRP B CG  1 
ATOM   4864 C CD1 . TRP B 1 231 ? 107.590 161.374 129.750 1.00 77.04  ? 231 TRP B CD1 1 
ATOM   4865 C CD2 . TRP B 1 231 ? 106.511 162.750 131.140 1.00 76.44  ? 231 TRP B CD2 1 
ATOM   4866 N NE1 . TRP B 1 231 ? 107.191 162.470 129.028 1.00 76.98  ? 231 TRP B NE1 1 
ATOM   4867 C CE2 . TRP B 1 231 ? 106.526 163.330 129.860 1.00 80.30  ? 231 TRP B CE2 1 
ATOM   4868 C CE3 . TRP B 1 231 ? 105.885 163.436 132.184 1.00 76.63  ? 231 TRP B CE3 1 
ATOM   4869 C CZ2 . TRP B 1 231 ? 105.939 164.562 129.593 1.00 83.91  ? 231 TRP B CZ2 1 
ATOM   4870 C CZ3 . TRP B 1 231 ? 105.303 164.659 131.918 1.00 76.44  ? 231 TRP B CZ3 1 
ATOM   4871 C CH2 . TRP B 1 231 ? 105.334 165.210 130.634 1.00 81.21  ? 231 TRP B CH2 1 
ATOM   4872 N N   . LEU B 1 232 ? 110.306 159.316 132.220 1.00 71.49  ? 232 LEU B N   1 
ATOM   4873 C CA  . LEU B 1 232 ? 111.723 159.347 131.877 1.00 72.98  ? 232 LEU B CA  1 
ATOM   4874 C C   . LEU B 1 232 ? 112.147 158.058 131.193 1.00 75.62  ? 232 LEU B C   1 
ATOM   4875 O O   . LEU B 1 232 ? 112.910 158.084 130.222 1.00 84.66  ? 232 LEU B O   1 
ATOM   4876 C CB  . LEU B 1 232 ? 112.567 159.586 133.126 1.00 75.07  ? 232 LEU B CB  1 
ATOM   4877 C CG  . LEU B 1 232 ? 114.064 159.345 132.937 1.00 74.45  ? 232 LEU B CG  1 
ATOM   4878 C CD1 . LEU B 1 232 ? 114.650 160.370 131.987 1.00 75.75  ? 232 LEU B CD1 1 
ATOM   4879 C CD2 . LEU B 1 232 ? 114.794 159.363 134.265 1.00 75.39  ? 232 LEU B CD2 1 
ATOM   4880 N N   . GLY B 1 233 ? 111.662 156.920 131.684 1.00 71.57  ? 233 GLY B N   1 
ATOM   4881 C CA  . GLY B 1 233 ? 111.993 155.657 131.054 1.00 72.85  ? 233 GLY B CA  1 
ATOM   4882 C C   . GLY B 1 233 ? 111.466 155.545 129.639 1.00 78.88  ? 233 GLY B C   1 
ATOM   4883 O O   . GLY B 1 233 ? 112.103 154.928 128.783 1.00 84.85  ? 233 GLY B O   1 
ATOM   4884 N N   . MET B 1 234 ? 110.300 156.132 129.373 1.00 76.19  ? 234 MET B N   1 
ATOM   4885 C CA  . MET B 1 234 ? 109.695 156.010 128.053 1.00 75.95  ? 234 MET B CA  1 
ATOM   4886 C C   . MET B 1 234 ? 110.388 156.895 127.029 1.00 76.38  ? 234 MET B C   1 
ATOM   4887 O O   . MET B 1 234 ? 110.575 156.486 125.879 1.00 76.24  ? 234 MET B O   1 
ATOM   4888 C CB  . MET B 1 234 ? 108.215 156.357 128.127 1.00 74.42  ? 234 MET B CB  1 
ATOM   4889 C CG  . MET B 1 234 ? 107.386 155.240 128.682 1.00 72.16  ? 234 MET B CG  1 
ATOM   4890 S SD  . MET B 1 234 ? 107.614 153.705 127.794 1.00 73.21  ? 234 MET B SD  1 
ATOM   4891 C CE  . MET B 1 234 ? 106.557 152.677 128.788 1.00 79.89  ? 234 MET B CE  1 
ATOM   4892 N N   . VAL B 1 235 ? 110.766 158.114 127.420 1.00 75.37  ? 235 VAL B N   1 
ATOM   4893 C CA  . VAL B 1 235 ? 111.462 158.991 126.492 1.00 76.67  ? 235 VAL B CA  1 
ATOM   4894 C C   . VAL B 1 235 ? 112.854 158.465 126.174 1.00 80.99  ? 235 VAL B C   1 
ATOM   4895 O O   . VAL B 1 235 ? 113.405 158.786 125.116 1.00 87.33  ? 235 VAL B O   1 
ATOM   4896 C CB  . VAL B 1 235 ? 111.521 160.428 127.040 1.00 74.67  ? 235 VAL B CB  1 
ATOM   4897 C CG1 . VAL B 1 235 ? 112.647 160.580 128.046 1.00 73.68  ? 235 VAL B CG1 1 
ATOM   4898 C CG2 . VAL B 1 235 ? 111.675 161.418 125.902 1.00 78.25  ? 235 VAL B CG2 1 
ATOM   4899 N N   . VAL B 1 236 ? 113.440 157.659 127.061 1.00 70.61  ? 236 VAL B N   1 
ATOM   4900 C CA  . VAL B 1 236 ? 114.714 157.025 126.746 1.00 69.84  ? 236 VAL B CA  1 
ATOM   4901 C C   . VAL B 1 236 ? 114.528 155.953 125.681 1.00 80.56  ? 236 VAL B C   1 
ATOM   4902 O O   . VAL B 1 236 ? 115.314 155.862 124.732 1.00 84.71  ? 236 VAL B O   1 
ATOM   4903 C CB  . VAL B 1 236 ? 115.359 156.456 128.020 1.00 69.33  ? 236 VAL B CB  1 
ATOM   4904 C CG1 . VAL B 1 236 ? 116.517 155.551 127.658 1.00 75.00  ? 236 VAL B CG1 1 
ATOM   4905 C CG2 . VAL B 1 236 ? 115.834 157.583 128.912 1.00 71.92  ? 236 VAL B CG2 1 
ATOM   4906 N N   . CYS B 1 237 ? 113.486 155.127 125.815 1.00 80.30  ? 237 CYS B N   1 
ATOM   4907 C CA  . CYS B 1 237 ? 113.203 154.128 124.787 1.00 77.60  ? 237 CYS B CA  1 
ATOM   4908 C C   . CYS B 1 237 ? 112.881 154.781 123.453 1.00 80.34  ? 237 CYS B C   1 
ATOM   4909 O O   . CYS B 1 237 ? 113.339 154.318 122.403 1.00 82.09  ? 237 CYS B O   1 
ATOM   4910 C CB  . CYS B 1 237 ? 112.054 153.225 125.219 1.00 75.41  ? 237 CYS B CB  1 
ATOM   4911 S SG  . CYS B 1 237 ? 112.591 151.751 126.067 1.00 85.70  ? 237 CYS B SG  1 
ATOM   4912 N N   . ARG B 1 238 ? 112.084 155.849 123.472 1.00 88.23  ? 238 ARG B N   1 
ATOM   4913 C CA  . ARG B 1 238 ? 111.795 156.565 122.237 1.00 88.10  ? 238 ARG B CA  1 
ATOM   4914 C C   . ARG B 1 238 ? 113.081 157.020 121.566 1.00 93.80  ? 238 ARG B C   1 
ATOM   4915 O O   . ARG B 1 238 ? 113.201 156.974 120.337 1.00 96.79  ? 238 ARG B O   1 
ATOM   4916 C CB  . ARG B 1 238 ? 110.890 157.762 122.523 1.00 89.25  ? 238 ARG B CB  1 
ATOM   4917 C CG  . ARG B 1 238 ? 109.844 158.021 121.457 1.00 90.12  ? 238 ARG B CG  1 
ATOM   4918 C CD  . ARG B 1 238 ? 108.488 157.445 121.843 1.00 91.03  ? 238 ARG B CD  1 
ATOM   4919 N NE  . ARG B 1 238 ? 108.045 157.915 123.150 1.00 94.58  ? 238 ARG B NE  1 
ATOM   4920 C CZ  . ARG B 1 238 ? 107.641 159.152 123.409 1.00 95.51  ? 238 ARG B CZ  1 
ATOM   4921 N NH1 . ARG B 1 238 ? 107.595 160.078 122.466 1.00 92.35  ? 238 ARG B NH1 1 
ATOM   4922 N NH2 . ARG B 1 238 ? 107.275 159.469 124.648 1.00 94.58  ? 238 ARG B NH2 1 
ATOM   4923 N N   . PHE B 1 239 ? 114.056 157.461 122.361 1.00 87.69  ? 239 PHE B N   1 
ATOM   4924 C CA  . PHE B 1 239 ? 115.343 157.858 121.805 1.00 85.49  ? 239 PHE B CA  1 
ATOM   4925 C C   . PHE B 1 239 ? 116.111 156.646 121.290 1.00 86.60  ? 239 PHE B C   1 
ATOM   4926 O O   . PHE B 1 239 ? 116.582 156.637 120.148 1.00 91.97  ? 239 PHE B O   1 
ATOM   4927 C CB  . PHE B 1 239 ? 116.152 158.602 122.868 1.00 80.20  ? 239 PHE B CB  1 
ATOM   4928 C CG  . PHE B 1 239 ? 117.466 159.142 122.378 1.00 84.67  ? 239 PHE B CG  1 
ATOM   4929 C CD1 . PHE B 1 239 ? 117.699 159.343 121.029 1.00 90.83  ? 239 PHE B CD1 1 
ATOM   4930 C CD2 . PHE B 1 239 ? 118.474 159.441 123.276 1.00 85.15  ? 239 PHE B CD2 1 
ATOM   4931 C CE1 . PHE B 1 239 ? 118.908 159.835 120.587 1.00 91.92  ? 239 PHE B CE1 1 
ATOM   4932 C CE2 . PHE B 1 239 ? 119.683 159.934 122.840 1.00 90.94  ? 239 PHE B CE2 1 
ATOM   4933 C CZ  . PHE B 1 239 ? 119.901 160.131 121.493 1.00 91.95  ? 239 PHE B CZ  1 
ATOM   4934 N N   . LEU B 1 240 ? 116.221 155.601 122.110 1.00 80.37  ? 240 LEU B N   1 
ATOM   4935 C CA  . LEU B 1 240 ? 117.109 154.491 121.777 1.00 84.41  ? 240 LEU B CA  1 
ATOM   4936 C C   . LEU B 1 240 ? 116.590 153.672 120.604 1.00 88.48  ? 240 LEU B C   1 
ATOM   4937 O O   . LEU B 1 240 ? 117.383 153.062 119.880 1.00 89.03  ? 240 LEU B O   1 
ATOM   4938 C CB  . LEU B 1 240 ? 117.313 153.595 122.995 1.00 77.94  ? 240 LEU B CB  1 
ATOM   4939 C CG  . LEU B 1 240 ? 118.537 153.894 123.856 1.00 74.37  ? 240 LEU B CG  1 
ATOM   4940 C CD1 . LEU B 1 240 ? 118.522 155.331 124.337 1.00 86.61  ? 240 LEU B CD1 1 
ATOM   4941 C CD2 . LEU B 1 240 ? 118.586 152.950 125.031 1.00 72.21  ? 240 LEU B CD2 1 
ATOM   4942 N N   . GLU B 1 241 ? 115.275 153.635 120.403 1.00 95.10  ? 241 GLU B N   1 
ATOM   4943 C CA  . GLU B 1 241 ? 114.730 152.827 119.321 1.00 93.85  ? 241 GLU B CA  1 
ATOM   4944 C C   . GLU B 1 241 ? 114.969 153.467 117.960 1.00 96.32  ? 241 GLU B C   1 
ATOM   4945 O O   . GLU B 1 241 ? 115.274 152.766 116.990 1.00 99.09  ? 241 GLU B O   1 
ATOM   4946 C CB  . GLU B 1 241 ? 113.241 152.588 119.547 1.00 90.56  ? 241 GLU B CB  1 
ATOM   4947 C CG  . GLU B 1 241 ? 112.961 151.414 120.451 1.00 91.84  ? 241 GLU B CG  1 
ATOM   4948 C CD  . GLU B 1 241 ? 111.491 151.104 120.549 1.00 97.83  ? 241 GLU B CD  1 
ATOM   4949 O OE1 . GLU B 1 241 ? 110.726 151.601 119.697 1.00 96.70  ? 241 GLU B OE1 1 
ATOM   4950 O OE2 . GLU B 1 241 ? 111.096 150.366 121.476 1.00 98.68  ? 241 GLU B OE2 1 
ATOM   4951 N N   . MET B 1 242 ? 114.839 154.787 117.864 1.00 94.79  ? 242 MET B N   1 
ATOM   4952 C CA  . MET B 1 242 ? 115.105 155.489 116.617 1.00 95.84  ? 242 MET B CA  1 
ATOM   4953 C C   . MET B 1 242 ? 116.526 156.024 116.525 1.00 99.11  ? 242 MET B C   1 
ATOM   4954 O O   . MET B 1 242 ? 116.804 156.854 115.654 1.00 101.52 ? 242 MET B O   1 
ATOM   4955 C CB  . MET B 1 242 ? 114.110 156.634 116.418 1.00 97.86  ? 242 MET B CB  1 
ATOM   4956 C CG  . MET B 1 242 ? 112.748 156.404 117.038 1.00 100.87 ? 242 MET B CG  1 
ATOM   4957 S SD  . MET B 1 242 ? 111.746 157.901 116.996 1.00 115.84 ? 242 MET B SD  1 
ATOM   4958 C CE  . MET B 1 242 ? 110.369 157.412 118.024 1.00 101.05 ? 242 MET B CE  1 
ATOM   4959 N N   . ARG B 1 243 ? 117.422 155.584 117.401 1.00 91.06  ? 243 ARG B N   1 
ATOM   4960 C CA  . ARG B 1 243 ? 118.828 155.932 117.283 1.00 91.01  ? 243 ARG B CA  1 
ATOM   4961 C C   . ARG B 1 243 ? 119.567 154.856 116.499 1.00 95.42  ? 243 ARG B C   1 
ATOM   4962 O O   . ARG B 1 243 ? 119.417 153.661 116.766 1.00 95.03  ? 243 ARG B O   1 
ATOM   4963 C CB  . ARG B 1 243 ? 119.451 156.106 118.667 1.00 89.61  ? 243 ARG B CB  1 
ATOM   4964 C CG  . ARG B 1 243 ? 120.926 155.771 118.731 1.00 91.20  ? 243 ARG B CG  1 
ATOM   4965 C CD  . ARG B 1 243 ? 121.406 155.639 120.166 1.00 92.46  ? 243 ARG B CD  1 
ATOM   4966 N NE  . ARG B 1 243 ? 122.831 155.342 120.234 1.00 93.70  ? 243 ARG B NE  1 
ATOM   4967 C CZ  . ARG B 1 243 ? 123.795 156.220 119.996 1.00 94.43  ? 243 ARG B CZ  1 
ATOM   4968 N NH1 . ARG B 1 243 ? 123.524 157.479 119.689 1.00 95.92  ? 243 ARG B NH1 1 
ATOM   4969 N NH2 . ARG B 1 243 ? 125.063 155.827 120.069 1.00 94.36  ? 243 ARG B NH2 1 
ATOM   4970 N N   . THR B 1 244 ? 120.357 155.285 115.518 1.00 94.89  ? 244 THR B N   1 
ATOM   4971 C CA  . THR B 1 244 ? 121.152 154.371 114.710 1.00 92.69  ? 244 THR B CA  1 
ATOM   4972 C C   . THR B 1 244 ? 122.486 154.110 115.394 1.00 92.96  ? 244 THR B C   1 
ATOM   4973 O O   . THR B 1 244 ? 123.124 155.032 115.908 1.00 94.73  ? 244 THR B O   1 
ATOM   4974 C CB  . THR B 1 244 ? 121.391 154.941 113.314 1.00 90.89  ? 244 THR B CB  1 
ATOM   4975 O OG1 . THR B 1 244 ? 122.448 155.904 113.370 1.00 91.88  ? 244 THR B OG1 1 
ATOM   4976 C CG2 . THR B 1 244 ? 120.133 155.615 112.799 1.00 90.90  ? 244 THR B CG2 1 
ATOM   4977 N N   . TYR B 1 245 ? 122.905 152.849 115.392 1.00 82.38  ? 245 TYR B N   1 
ATOM   4978 C CA  . TYR B 1 245 ? 124.078 152.417 116.139 1.00 83.76  ? 245 TYR B CA  1 
ATOM   4979 C C   . TYR B 1 245 ? 125.258 152.244 115.190 1.00 87.76  ? 245 TYR B C   1 
ATOM   4980 O O   . TYR B 1 245 ? 125.195 151.447 114.249 1.00 89.77  ? 245 TYR B O   1 
ATOM   4981 C CB  . TYR B 1 245 ? 123.772 151.129 116.898 1.00 81.85  ? 245 TYR B CB  1 
ATOM   4982 C CG  . TYR B 1 245 ? 122.682 151.327 117.924 1.00 84.21  ? 245 TYR B CG  1 
ATOM   4983 C CD1 . TYR B 1 245 ? 122.963 151.884 119.163 1.00 83.02  ? 245 TYR B CD1 1 
ATOM   4984 C CD2 . TYR B 1 245 ? 121.370 150.987 117.645 1.00 88.27  ? 245 TYR B CD2 1 
ATOM   4985 C CE1 . TYR B 1 245 ? 121.973 152.080 120.099 1.00 79.81  ? 245 TYR B CE1 1 
ATOM   4986 C CE2 . TYR B 1 245 ? 120.372 151.181 118.575 1.00 89.24  ? 245 TYR B CE2 1 
ATOM   4987 C CZ  . TYR B 1 245 ? 120.680 151.728 119.799 1.00 86.88  ? 245 TYR B CZ  1 
ATOM   4988 O OH  . TYR B 1 245 ? 119.688 151.921 120.727 1.00 92.91  ? 245 TYR B OH  1 
ATOM   4989 N N   . HIS B 1 246 ? 126.329 152.989 115.448 1.00 90.80  ? 246 HIS B N   1 
ATOM   4990 C CA  . HIS B 1 246 ? 127.490 153.103 114.570 1.00 91.66  ? 246 HIS B CA  1 
ATOM   4991 C C   . HIS B 1 246 ? 128.763 152.801 115.373 1.00 93.39  ? 246 HIS B C   1 
ATOM   4992 O O   . HIS B 1 246 ? 129.734 153.557 115.409 1.00 95.31  ? 246 HIS B O   1 
ATOM   4993 C CB  . HIS B 1 246 ? 127.436 154.478 113.882 1.00 93.98  ? 246 HIS B CB  1 
ATOM   4994 C CG  . HIS B 1 246 ? 128.769 155.082 113.564 1.00 97.29  ? 246 HIS B CG  1 
ATOM   4995 N ND1 . HIS B 1 246 ? 129.731 154.419 112.833 1.00 95.00  ? 246 HIS B ND1 1 
ATOM   4996 C CD2 . HIS B 1 246 ? 129.304 156.281 113.891 1.00 93.42  ? 246 HIS B CD2 1 
ATOM   4997 C CE1 . HIS B 1 246 ? 130.800 155.187 112.718 1.00 94.40  ? 246 HIS B CE1 1 
ATOM   4998 N NE2 . HIS B 1 246 ? 130.566 156.323 113.351 1.00 95.34  ? 246 HIS B NE2 1 
ATOM   4999 N N   . TRP B 1 247 ? 128.740 151.680 116.084 1.00 81.24  ? 247 TRP B N   1 
ATOM   5000 C CA  . TRP B 1 247 ? 129.874 151.295 116.914 1.00 81.33  ? 247 TRP B CA  1 
ATOM   5001 C C   . TRP B 1 247 ? 131.092 151.018 116.045 1.00 83.62  ? 247 TRP B C   1 
ATOM   5002 O O   . TRP B 1 247 ? 131.095 150.080 115.241 1.00 80.36  ? 247 TRP B O   1 
ATOM   5003 C CB  . TRP B 1 247 ? 129.514 150.074 117.752 1.00 77.38  ? 247 TRP B CB  1 
ATOM   5004 C CG  . TRP B 1 247 ? 128.311 150.313 118.576 1.00 71.20  ? 247 TRP B CG  1 
ATOM   5005 C CD1 . TRP B 1 247 ? 127.100 149.718 118.443 1.00 71.84  ? 247 TRP B CD1 1 
ATOM   5006 C CD2 . TRP B 1 247 ? 128.188 151.243 119.654 1.00 74.67  ? 247 TRP B CD2 1 
ATOM   5007 N NE1 . TRP B 1 247 ? 126.229 150.210 119.377 1.00 75.68  ? 247 TRP B NE1 1 
ATOM   5008 C CE2 . TRP B 1 247 ? 126.875 151.150 120.135 1.00 73.80  ? 247 TRP B CE2 1 
ATOM   5009 C CE3 . TRP B 1 247 ? 129.067 152.141 120.262 1.00 79.29  ? 247 TRP B CE3 1 
ATOM   5010 C CZ2 . TRP B 1 247 ? 126.414 151.920 121.195 1.00 74.82  ? 247 TRP B CZ2 1 
ATOM   5011 C CZ3 . TRP B 1 247 ? 128.610 152.904 121.312 1.00 76.37  ? 247 TRP B CZ3 1 
ATOM   5012 C CH2 . TRP B 1 247 ? 127.297 152.789 121.770 1.00 75.85  ? 247 TRP B CH2 1 
ATOM   5013 N N   . ALA B 1 248 ? 132.123 151.838 116.208 1.00 90.21  ? 248 ALA B N   1 
ATOM   5014 C CA  . ALA B 1 248 ? 133.371 151.713 115.474 1.00 88.44  ? 248 ALA B CA  1 
ATOM   5015 C C   . ALA B 1 248 ? 134.448 151.130 116.375 1.00 88.57  ? 248 ALA B C   1 
ATOM   5016 O O   . ALA B 1 248 ? 134.274 150.993 117.588 1.00 89.70  ? 248 ALA B O   1 
ATOM   5017 C CB  . ALA B 1 248 ? 133.817 153.071 114.920 1.00 89.42  ? 248 ALA B CB  1 
ATOM   5018 N N   . SER B 1 249 ? 135.571 150.778 115.759 1.00 102.56 ? 249 SER B N   1 
ATOM   5019 C CA  . SER B 1 249 ? 136.689 150.222 116.506 1.00 105.94 ? 249 SER B CA  1 
ATOM   5020 C C   . SER B 1 249 ? 137.264 151.258 117.461 1.00 105.40 ? 249 SER B C   1 
ATOM   5021 O O   . SER B 1 249 ? 137.453 152.421 117.096 1.00 105.09 ? 249 SER B O   1 
ATOM   5022 C CB  . SER B 1 249 ? 137.770 149.735 115.544 1.00 104.73 ? 249 SER B CB  1 
ATOM   5023 O OG  . SER B 1 249 ? 138.580 148.748 116.154 1.00 105.68 ? 249 SER B OG  1 
ATOM   5024 N N   . PHE B 1 250 ? 137.540 150.831 118.694 1.00 94.23  ? 250 PHE B N   1 
ATOM   5025 C CA  . PHE B 1 250 ? 138.205 151.717 119.641 1.00 93.14  ? 250 PHE B CA  1 
ATOM   5026 C C   . PHE B 1 250 ? 139.596 152.091 119.156 1.00 94.44  ? 250 PHE B C   1 
ATOM   5027 O O   . PHE B 1 250 ? 140.060 153.210 119.399 1.00 95.32  ? 250 PHE B O   1 
ATOM   5028 C CB  . PHE B 1 250 ? 138.272 151.052 121.016 1.00 94.23  ? 250 PHE B CB  1 
ATOM   5029 C CG  . PHE B 1 250 ? 138.932 151.892 122.073 1.00 95.81  ? 250 PHE B CG  1 
ATOM   5030 C CD1 . PHE B 1 250 ? 140.292 151.799 122.304 1.00 95.32  ? 250 PHE B CD1 1 
ATOM   5031 C CD2 . PHE B 1 250 ? 138.190 152.761 122.847 1.00 95.99  ? 250 PHE B CD2 1 
ATOM   5032 C CE1 . PHE B 1 250 ? 140.897 152.561 123.277 1.00 93.46  ? 250 PHE B CE1 1 
ATOM   5033 C CE2 . PHE B 1 250 ? 138.791 153.524 123.821 1.00 94.39  ? 250 PHE B CE2 1 
ATOM   5034 C CZ  . PHE B 1 250 ? 140.146 153.424 124.035 1.00 93.48  ? 250 PHE B CZ  1 
ATOM   5035 N N   . LYS B 1 251 ? 140.276 151.168 118.474 1.00 102.81 ? 251 LYS B N   1 
ATOM   5036 C CA  . LYS B 1 251 ? 141.602 151.462 117.945 1.00 104.61 ? 251 LYS B CA  1 
ATOM   5037 C C   . LYS B 1 251 ? 141.538 152.484 116.818 1.00 103.69 ? 251 LYS B C   1 
ATOM   5038 O O   . LYS B 1 251 ? 142.385 153.380 116.736 1.00 105.10 ? 251 LYS B O   1 
ATOM   5039 C CB  . LYS B 1 251 ? 142.266 150.174 117.461 1.00 102.34 ? 251 LYS B CB  1 
ATOM   5040 C CG  . LYS B 1 251 ? 142.241 149.047 118.478 1.00 100.57 ? 251 LYS B CG  1 
ATOM   5041 C CD  . LYS B 1 251 ? 142.400 147.689 117.812 1.00 100.52 ? 251 LYS B CD  1 
ATOM   5042 C CE  . LYS B 1 251 ? 141.608 147.611 116.518 1.00 103.78 ? 251 LYS B CE  1 
ATOM   5043 N NZ  . LYS B 1 251 ? 141.478 146.212 116.026 1.00 105.00 ? 251 LYS B NZ  1 
ATOM   5044 N N   . ASP B 1 252 ? 140.540 152.368 115.939 1.00 103.10 ? 252 ASP B N   1 
ATOM   5045 C CA  . ASP B 1 252 ? 140.478 153.245 114.775 1.00 104.76 ? 252 ASP B CA  1 
ATOM   5046 C C   . ASP B 1 252 ? 140.264 154.698 115.172 1.00 107.72 ? 252 ASP B C   1 
ATOM   5047 O O   . ASP B 1 252 ? 140.731 155.604 114.473 1.00 110.69 ? 252 ASP B O   1 
ATOM   5048 C CB  . ASP B 1 252 ? 139.374 152.782 113.827 1.00 108.48 ? 252 ASP B CB  1 
ATOM   5049 C CG  . ASP B 1 252 ? 139.899 151.899 112.712 1.00 111.88 ? 252 ASP B CG  1 
ATOM   5050 O OD1 . ASP B 1 252 ? 140.958 152.229 112.139 1.00 111.30 ? 252 ASP B OD1 1 
ATOM   5051 O OD2 . ASP B 1 252 ? 139.254 150.874 112.407 1.00 112.92 ? 252 ASP B OD2 1 
ATOM   5052 N N   . ILE B 1 253 ? 139.559 154.943 116.278 1.00 104.95 ? 253 ILE B N   1 
ATOM   5053 C CA  . ILE B 1 253 ? 139.378 156.308 116.752 1.00 107.31 ? 253 ILE B CA  1 
ATOM   5054 C C   . ILE B 1 253 ? 140.734 156.888 117.130 1.00 107.06 ? 253 ILE B C   1 
ATOM   5055 O O   . ILE B 1 253 ? 141.570 156.215 117.744 1.00 106.09 ? 253 ILE B O   1 
ATOM   5056 C CB  . ILE B 1 253 ? 138.394 156.337 117.934 1.00 107.62 ? 253 ILE B CB  1 
ATOM   5057 C CG1 . ILE B 1 253 ? 136.973 156.060 117.444 1.00 105.78 ? 253 ILE B CG1 1 
ATOM   5058 C CG2 . ILE B 1 253 ? 138.432 157.675 118.643 1.00 104.44 ? 253 ILE B CG2 1 
ATOM   5059 C CD1 . ILE B 1 253 ? 136.530 156.973 116.323 1.00 104.82 ? 253 ILE B CD1 1 
ATOM   5060 N N   . HIS B 1 254 ? 140.968 158.141 116.740 1.00 107.81 ? 254 HIS B N   1 
ATOM   5061 C CA  . HIS B 1 254 ? 142.257 158.789 116.948 1.00 108.58 ? 254 HIS B CA  1 
ATOM   5062 C C   . HIS B 1 254 ? 142.239 159.809 118.081 1.00 108.01 ? 254 HIS B C   1 
ATOM   5063 O O   . HIS B 1 254 ? 143.084 159.750 118.978 1.00 106.09 ? 254 HIS B O   1 
ATOM   5064 C CB  . HIS B 1 254 ? 142.715 159.462 115.650 1.00 107.45 ? 254 HIS B CB  1 
ATOM   5065 C CG  . HIS B 1 254 ? 143.050 158.496 114.559 1.00 108.32 ? 254 HIS B CG  1 
ATOM   5066 N ND1 . HIS B 1 254 ? 143.410 157.189 114.808 1.00 108.47 ? 254 HIS B ND1 1 
ATOM   5067 C CD2 . HIS B 1 254 ? 143.078 158.644 113.214 1.00 107.21 ? 254 HIS B CD2 1 
ATOM   5068 C CE1 . HIS B 1 254 ? 143.646 156.574 113.664 1.00 107.45 ? 254 HIS B CE1 1 
ATOM   5069 N NE2 . HIS B 1 254 ? 143.452 157.435 112.681 1.00 108.27 ? 254 HIS B NE2 1 
ATOM   5070 N N   . THR B 1 255 ? 141.295 160.746 118.054 1.00 110.71 ? 255 THR B N   1 
ATOM   5071 C CA  . THR B 1 255 ? 141.269 161.811 119.048 1.00 111.12 ? 255 THR B CA  1 
ATOM   5072 C C   . THR B 1 255 ? 141.009 161.249 120.440 1.00 108.48 ? 255 THR B C   1 
ATOM   5073 O O   . THR B 1 255 ? 140.280 160.270 120.616 1.00 107.52 ? 255 THR B O   1 
ATOM   5074 C CB  . THR B 1 255 ? 140.200 162.842 118.695 1.00 109.93 ? 255 THR B CB  1 
ATOM   5075 O OG1 . THR B 1 255 ? 138.928 162.398 119.182 1.00 109.90 ? 255 THR B OG1 1 
ATOM   5076 C CG2 . THR B 1 255 ? 140.121 163.027 117.189 1.00 107.32 ? 255 THR B CG2 1 
ATOM   5077 N N   . THR B 1 256 ? 141.628 161.882 121.440 1.00 110.28 ? 256 THR B N   1 
ATOM   5078 C CA  . THR B 1 256 ? 141.479 161.417 122.815 1.00 112.60 ? 256 THR B CA  1 
ATOM   5079 C C   . THR B 1 256 ? 140.034 161.524 123.281 1.00 112.06 ? 256 THR B C   1 
ATOM   5080 O O   . THR B 1 256 ? 139.528 160.629 123.968 1.00 110.13 ? 256 THR B O   1 
ATOM   5081 C CB  . THR B 1 256 ? 142.397 162.211 123.744 1.00 111.26 ? 256 THR B CB  1 
ATOM   5082 O OG1 . THR B 1 256 ? 141.787 163.467 124.063 1.00 111.20 ? 256 THR B OG1 1 
ATOM   5083 C CG2 . THR B 1 256 ? 143.741 162.461 123.076 1.00 108.39 ? 256 THR B CG2 1 
ATOM   5084 N N   . THR B 1 257 ? 139.355 162.616 122.925 1.00 106.61 ? 257 THR B N   1 
ATOM   5085 C CA  . THR B 1 257 ? 137.956 162.764 123.309 1.00 106.37 ? 257 THR B CA  1 
ATOM   5086 C C   . THR B 1 257 ? 137.098 161.663 122.700 1.00 106.61 ? 257 THR B C   1 
ATOM   5087 O O   . THR B 1 257 ? 136.153 161.181 123.334 1.00 106.16 ? 257 THR B O   1 
ATOM   5088 C CB  . THR B 1 257 ? 137.440 164.147 122.906 1.00 109.02 ? 257 THR B CB  1 
ATOM   5089 O OG1 . THR B 1 257 ? 136.057 164.268 123.265 1.00 110.24 ? 257 THR B OG1 1 
ATOM   5090 C CG2 . THR B 1 257 ? 137.608 164.388 121.411 1.00 105.75 ? 257 THR B CG2 1 
ATOM   5091 N N   . GLY B 1 258 ? 137.412 161.248 121.471 1.00 103.16 ? 258 GLY B N   1 
ATOM   5092 C CA  . GLY B 1 258 ? 136.681 160.148 120.867 1.00 101.96 ? 258 GLY B CA  1 
ATOM   5093 C C   . GLY B 1 258 ? 136.921 158.829 121.576 1.00 101.52 ? 258 GLY B C   1 
ATOM   5094 O O   . GLY B 1 258 ? 135.990 158.047 121.782 1.00 100.94 ? 258 GLY B O   1 
ATOM   5095 N N   . LYS B 1 259 ? 138.173 158.562 121.955 1.00 101.18 ? 259 LYS B N   1 
ATOM   5096 C CA  . LYS B 1 259 ? 138.475 157.334 122.682 1.00 101.08 ? 259 LYS B CA  1 
ATOM   5097 C C   . LYS B 1 259 ? 137.760 157.303 124.024 1.00 100.68 ? 259 LYS B C   1 
ATOM   5098 O O   . LYS B 1 259 ? 137.215 156.267 124.422 1.00 102.66 ? 259 LYS B O   1 
ATOM   5099 C CB  . LYS B 1 259 ? 139.982 157.195 122.878 1.00 101.50 ? 259 LYS B CB  1 
ATOM   5100 C CG  . LYS B 1 259 ? 140.747 156.871 121.611 1.00 99.71  ? 259 LYS B CG  1 
ATOM   5101 C CD  . LYS B 1 259 ? 141.707 155.724 121.840 1.00 98.79  ? 259 LYS B CD  1 
ATOM   5102 C CE  . LYS B 1 259 ? 142.603 155.511 120.641 1.00 99.31  ? 259 LYS B CE  1 
ATOM   5103 N NZ  . LYS B 1 259 ? 142.626 156.711 119.763 1.00 100.98 ? 259 LYS B NZ  1 
ATOM   5104 N N   . ILE B 1 260 ? 137.754 158.428 124.739 1.00 92.79  ? 260 ILE B N   1 
ATOM   5105 C CA  . ILE B 1 260 ? 137.028 158.498 126.003 1.00 92.45  ? 260 ILE B CA  1 
ATOM   5106 C C   . ILE B 1 260 ? 135.535 158.334 125.767 1.00 92.59  ? 260 ILE B C   1 
ATOM   5107 O O   . ILE B 1 260 ? 134.851 157.610 126.500 1.00 92.14  ? 260 ILE B O   1 
ATOM   5108 C CB  . ILE B 1 260 ? 137.345 159.818 126.727 1.00 94.44  ? 260 ILE B CB  1 
ATOM   5109 C CG1 . ILE B 1 260 ? 138.828 159.878 127.090 1.00 96.98  ? 260 ILE B CG1 1 
ATOM   5110 C CG2 . ILE B 1 260 ? 136.487 159.960 127.967 1.00 95.20  ? 260 ILE B CG2 1 
ATOM   5111 C CD1 . ILE B 1 260 ? 139.354 158.605 127.717 1.00 95.19  ? 260 ILE B CD1 1 
ATOM   5112 N N   . LYS B 1 261 ? 135.006 158.997 124.737 1.00 91.75  ? 261 LYS B N   1 
ATOM   5113 C CA  . LYS B 1 261 ? 133.585 158.877 124.428 1.00 90.64  ? 261 LYS B CA  1 
ATOM   5114 C C   . LYS B 1 261 ? 133.221 157.442 124.085 1.00 90.32  ? 261 LYS B C   1 
ATOM   5115 O O   . LYS B 1 261 ? 132.164 156.948 124.491 1.00 94.57  ? 261 LYS B O   1 
ATOM   5116 C CB  . LYS B 1 261 ? 133.217 159.817 123.279 1.00 90.25  ? 261 LYS B CB  1 
ATOM   5117 C CG  . LYS B 1 261 ? 131.965 159.424 122.517 1.00 89.26  ? 261 LYS B CG  1 
ATOM   5118 C CD  . LYS B 1 261 ? 131.518 160.545 121.594 1.00 94.34  ? 261 LYS B CD  1 
ATOM   5119 C CE  . LYS B 1 261 ? 130.134 160.281 121.024 1.00 92.27  ? 261 LYS B CE  1 
ATOM   5120 N NZ  . LYS B 1 261 ? 129.063 160.892 121.856 1.00 91.01  ? 261 LYS B NZ  1 
ATOM   5121 N N   . ARG B 1 262 ? 134.086 156.756 123.338 1.00 80.24  ? 262 ARG B N   1 
ATOM   5122 C CA  . ARG B 1 262 ? 133.825 155.362 122.999 1.00 77.72  ? 262 ARG B CA  1 
ATOM   5123 C C   . ARG B 1 262 ? 133.823 154.481 124.241 1.00 77.70  ? 262 ARG B C   1 
ATOM   5124 O O   . ARG B 1 262 ? 133.006 153.560 124.352 1.00 81.30  ? 262 ARG B O   1 
ATOM   5125 C CB  . ARG B 1 262 ? 134.858 154.872 121.988 1.00 76.25  ? 262 ARG B CB  1 
ATOM   5126 C CG  . ARG B 1 262 ? 134.638 153.456 121.498 1.00 72.01  ? 262 ARG B CG  1 
ATOM   5127 C CD  . ARG B 1 262 ? 133.187 153.183 121.171 1.00 70.00  ? 262 ARG B CD  1 
ATOM   5128 N NE  . ARG B 1 262 ? 132.996 151.796 120.773 1.00 77.08  ? 262 ARG B NE  1 
ATOM   5129 C CZ  . ARG B 1 262 ? 132.902 150.782 121.620 1.00 76.72  ? 262 ARG B CZ  1 
ATOM   5130 N NH1 . ARG B 1 262 ? 132.935 150.970 122.927 1.00 73.50  ? 262 ARG B NH1 1 
ATOM   5131 N NH2 . ARG B 1 262 ? 132.770 149.549 121.144 1.00 80.38  ? 262 ARG B NH2 1 
ATOM   5132 N N   . ALA B 1 263 ? 134.728 154.743 125.183 1.00 74.06  ? 263 ALA B N   1 
ATOM   5133 C CA  . ALA B 1 263 ? 134.811 153.908 126.376 1.00 72.51  ? 263 ALA B CA  1 
ATOM   5134 C C   . ALA B 1 263 ? 133.542 154.008 127.211 1.00 77.31  ? 263 ALA B C   1 
ATOM   5135 O O   . ALA B 1 263 ? 132.932 152.991 127.557 1.00 79.76  ? 263 ALA B O   1 
ATOM   5136 C CB  . ALA B 1 263 ? 136.032 154.297 127.206 1.00 76.25  ? 263 ALA B CB  1 
ATOM   5137 N N   . VAL B 1 264 ? 133.122 155.232 127.539 1.00 81.52  ? 264 VAL B N   1 
ATOM   5138 C CA  . VAL B 1 264 ? 131.937 155.399 128.374 1.00 79.96  ? 264 VAL B CA  1 
ATOM   5139 C C   . VAL B 1 264 ? 130.691 154.924 127.642 1.00 80.44  ? 264 VAL B C   1 
ATOM   5140 O O   . VAL B 1 264 ? 129.770 154.382 128.262 1.00 80.13  ? 264 VAL B O   1 
ATOM   5141 C CB  . VAL B 1 264 ? 131.798 156.861 128.835 1.00 75.91  ? 264 VAL B CB  1 
ATOM   5142 C CG1 . VAL B 1 264 ? 132.861 157.195 129.863 1.00 76.29  ? 264 VAL B CG1 1 
ATOM   5143 C CG2 . VAL B 1 264 ? 131.885 157.806 127.654 1.00 78.75  ? 264 VAL B CG2 1 
ATOM   5144 N N   . LEU B 1 265 ? 130.636 155.114 126.323 1.00 80.75  ? 265 LEU B N   1 
ATOM   5145 C CA  . LEU B 1 265 ? 129.487 154.682 125.540 1.00 72.68  ? 265 LEU B CA  1 
ATOM   5146 C C   . LEU B 1 265 ? 129.350 153.171 125.474 1.00 78.53  ? 265 LEU B C   1 
ATOM   5147 O O   . LEU B 1 265 ? 128.302 152.685 125.039 1.00 80.05  ? 265 LEU B O   1 
ATOM   5148 C CB  . LEU B 1 265 ? 129.574 155.241 124.122 1.00 73.26  ? 265 LEU B CB  1 
ATOM   5149 C CG  . LEU B 1 265 ? 128.641 156.400 123.788 1.00 78.15  ? 265 LEU B CG  1 
ATOM   5150 C CD1 . LEU B 1 265 ? 127.219 155.908 123.620 1.00 82.28  ? 265 LEU B CD1 1 
ATOM   5151 C CD2 . LEU B 1 265 ? 128.710 157.463 124.867 1.00 79.09  ? 265 LEU B CD2 1 
ATOM   5152 N N   . GLN B 1 266 ? 130.376 152.416 125.871 1.00 80.83  ? 266 GLN B N   1 
ATOM   5153 C CA  . GLN B 1 266 ? 130.249 150.964 125.863 1.00 78.76  ? 266 GLN B CA  1 
ATOM   5154 C C   . GLN B 1 266 ? 129.207 150.489 126.864 1.00 79.86  ? 266 GLN B C   1 
ATOM   5155 O O   . GLN B 1 266 ? 128.455 149.551 126.585 1.00 81.87  ? 266 GLN B O   1 
ATOM   5156 C CB  . GLN B 1 266 ? 131.593 150.304 126.146 1.00 70.72  ? 266 GLN B CB  1 
ATOM   5157 C CG  . GLN B 1 266 ? 131.466 148.812 126.317 1.00 75.46  ? 266 GLN B CG  1 
ATOM   5158 C CD  . GLN B 1 266 ? 132.511 148.056 125.553 1.00 80.66  ? 266 GLN B CD  1 
ATOM   5159 O OE1 . GLN B 1 266 ? 133.456 148.644 125.037 1.00 83.26  ? 266 GLN B OE1 1 
ATOM   5160 N NE2 . GLN B 1 266 ? 132.339 146.746 125.452 1.00 77.10  ? 266 GLN B NE2 1 
ATOM   5161 N N   . PHE B 1 267 ? 129.145 151.119 128.034 1.00 75.89  ? 267 PHE B N   1 
ATOM   5162 C CA  . PHE B 1 267 ? 128.170 150.703 129.031 1.00 73.72  ? 267 PHE B CA  1 
ATOM   5163 C C   . PHE B 1 267 ? 126.738 150.907 128.556 1.00 75.91  ? 267 PHE B C   1 
ATOM   5164 O O   . PHE B 1 267 ? 125.829 150.245 129.064 1.00 79.61  ? 267 PHE B O   1 
ATOM   5165 C CB  . PHE B 1 267 ? 128.424 151.448 130.336 1.00 76.57  ? 267 PHE B CB  1 
ATOM   5166 C CG  . PHE B 1 267 ? 129.724 151.084 130.987 1.00 78.03  ? 267 PHE B CG  1 
ATOM   5167 C CD1 . PHE B 1 267 ? 130.259 149.822 130.820 1.00 77.11  ? 267 PHE B CD1 1 
ATOM   5168 C CD2 . PHE B 1 267 ? 130.415 152.001 131.753 1.00 79.81  ? 267 PHE B CD2 1 
ATOM   5169 C CE1 . PHE B 1 267 ? 131.455 149.477 131.409 1.00 75.85  ? 267 PHE B CE1 1 
ATOM   5170 C CE2 . PHE B 1 267 ? 131.612 151.660 132.345 1.00 82.08  ? 267 PHE B CE2 1 
ATOM   5171 C CZ  . PHE B 1 267 ? 132.131 150.393 132.171 1.00 78.72  ? 267 PHE B CZ  1 
ATOM   5172 N N   . THR B 1 268 ? 126.514 151.797 127.596 1.00 66.72  ? 268 THR B N   1 
ATOM   5173 C CA  . THR B 1 268 ? 125.202 151.904 126.986 1.00 69.84  ? 268 THR B CA  1 
ATOM   5174 C C   . THR B 1 268 ? 124.949 150.702 126.077 1.00 71.59  ? 268 THR B C   1 
ATOM   5175 O O   . THR B 1 268 ? 125.892 150.083 125.581 1.00 76.97  ? 268 THR B O   1 
ATOM   5176 C CB  . THR B 1 268 ? 125.085 153.196 126.186 1.00 71.70  ? 268 THR B CB  1 
ATOM   5177 O OG1 . THR B 1 268 ? 126.307 153.432 125.481 1.00 73.59  ? 268 THR B OG1 1 
ATOM   5178 C CG2 . THR B 1 268 ? 124.807 154.366 127.109 1.00 74.68  ? 268 THR B CG2 1 
ATOM   5179 N N   . PRO B 1 269 ? 123.687 150.343 125.851 1.00 65.87  ? 269 PRO B N   1 
ATOM   5180 C CA  . PRO B 1 269 ? 123.394 149.182 125.005 1.00 65.03  ? 269 PRO B CA  1 
ATOM   5181 C C   . PRO B 1 269 ? 123.839 149.389 123.567 1.00 68.64  ? 269 PRO B C   1 
ATOM   5182 O O   . PRO B 1 269 ? 123.845 150.506 123.048 1.00 71.89  ? 269 PRO B O   1 
ATOM   5183 C CB  . PRO B 1 269 ? 121.871 149.052 125.099 1.00 66.19  ? 269 PRO B CB  1 
ATOM   5184 C CG  . PRO B 1 269 ? 121.404 150.381 125.553 1.00 70.47  ? 269 PRO B CG  1 
ATOM   5185 C CD  . PRO B 1 269 ? 122.466 150.892 126.455 1.00 69.79  ? 269 PRO B CD  1 
ATOM   5186 N N   . ALA B 1 270 ? 124.213 148.282 122.922 1.00 64.76  ? 270 ALA B N   1 
ATOM   5187 C CA  . ALA B 1 270 ? 124.609 148.307 121.520 1.00 64.97  ? 270 ALA B CA  1 
ATOM   5188 C C   . ALA B 1 270 ? 123.423 148.314 120.569 1.00 70.90  ? 270 ALA B C   1 
ATOM   5189 O O   . ALA B 1 270 ? 123.567 148.752 119.424 1.00 72.50  ? 270 ALA B O   1 
ATOM   5190 C CB  . ALA B 1 270 ? 125.496 147.107 121.198 1.00 61.53  ? 270 ALA B CB  1 
ATOM   5191 N N   . SER B 1 271 ? 122.266 147.830 121.007 1.00 75.25  ? 271 SER B N   1 
ATOM   5192 C CA  . SER B 1 271 ? 121.080 147.820 120.168 1.00 69.99  ? 271 SER B CA  1 
ATOM   5193 C C   . SER B 1 271 ? 119.856 147.758 121.067 1.00 74.43  ? 271 SER B C   1 
ATOM   5194 O O   . SER B 1 271 ? 119.926 147.306 122.211 1.00 75.70  ? 271 SER B O   1 
ATOM   5195 C CB  . SER B 1 271 ? 121.097 146.645 119.188 1.00 67.92  ? 271 SER B CB  1 
ATOM   5196 O OG  . SER B 1 271 ? 121.080 145.410 119.878 1.00 73.66  ? 271 SER B OG  1 
ATOM   5197 N N   . TRP B 1 272 ? 118.730 148.221 120.533 1.00 79.05  ? 272 TRP B N   1 
ATOM   5198 C CA  . TRP B 1 272 ? 117.462 148.210 121.251 1.00 79.64  ? 272 TRP B CA  1 
ATOM   5199 C C   . TRP B 1 272 ? 116.399 147.561 120.386 1.00 81.56  ? 272 TRP B C   1 
ATOM   5200 O O   . TRP B 1 272 ? 116.062 148.076 119.317 1.00 83.74  ? 272 TRP B O   1 
ATOM   5201 C CB  . TRP B 1 272 ? 117.043 149.622 121.663 1.00 77.63  ? 272 TRP B CB  1 
ATOM   5202 C CG  . TRP B 1 272 ? 116.237 149.628 122.913 1.00 79.95  ? 272 TRP B CG  1 
ATOM   5203 C CD1 . TRP B 1 272 ? 114.880 149.583 123.007 1.00 80.21  ? 272 TRP B CD1 1 
ATOM   5204 C CD2 . TRP B 1 272 ? 116.732 149.590 124.252 1.00 80.22  ? 272 TRP B CD2 1 
ATOM   5205 N NE1 . TRP B 1 272 ? 114.496 149.569 124.323 1.00 77.03  ? 272 TRP B NE1 1 
ATOM   5206 C CE2 . TRP B 1 272 ? 115.618 149.566 125.108 1.00 83.12  ? 272 TRP B CE2 1 
ATOM   5207 C CE3 . TRP B 1 272 ? 118.011 149.588 124.812 1.00 76.14  ? 272 TRP B CE3 1 
ATOM   5208 C CZ2 . TRP B 1 272 ? 115.744 149.547 126.492 1.00 85.01  ? 272 TRP B CZ2 1 
ATOM   5209 C CZ3 . TRP B 1 272 ? 118.131 149.570 126.185 1.00 77.41  ? 272 TRP B CZ3 1 
ATOM   5210 C CH2 . TRP B 1 272 ? 117.008 149.549 127.009 1.00 79.23  ? 272 TRP B CH2 1 
ATOM   5211 N N   . THR B 1 273 ? 115.878 146.431 120.851 1.00 77.89  ? 273 THR B N   1 
ATOM   5212 C CA  . THR B 1 273 ? 114.843 145.728 120.114 1.00 78.40  ? 273 THR B CA  1 
ATOM   5213 C C   . THR B 1 273 ? 113.512 146.456 120.230 1.00 78.65  ? 273 THR B C   1 
ATOM   5214 O O   . THR B 1 273 ? 113.169 146.999 121.283 1.00 81.22  ? 273 THR B O   1 
ATOM   5215 C CB  . THR B 1 273 ? 114.703 144.299 120.628 1.00 82.69  ? 273 THR B CB  1 
ATOM   5216 O OG1 . THR B 1 273 ? 113.509 143.715 120.095 1.00 84.54  ? 273 THR B OG1 1 
ATOM   5217 C CG2 . THR B 1 273 ? 114.633 144.287 122.138 1.00 77.10  ? 273 THR B CG2 1 
ATOM   5218 N N   . TYR B 1 274 ? 112.764 146.468 119.133 1.00 80.83  ? 274 TYR B N   1 
ATOM   5219 C CA  . TYR B 1 274 ? 111.426 147.045 119.112 1.00 76.90  ? 274 TYR B CA  1 
ATOM   5220 C C   . TYR B 1 274 ? 110.462 146.077 119.781 1.00 77.86  ? 274 TYR B C   1 
ATOM   5221 O O   . TYR B 1 274 ? 110.122 145.039 119.208 1.00 83.91  ? 274 TYR B O   1 
ATOM   5222 C CB  . TYR B 1 274 ? 111.013 147.328 117.672 1.00 83.05  ? 274 TYR B CB  1 
ATOM   5223 C CG  . TYR B 1 274 ? 109.688 148.032 117.522 1.00 89.37  ? 274 TYR B CG  1 
ATOM   5224 C CD1 . TYR B 1 274 ? 108.721 147.549 116.652 1.00 88.48  ? 274 TYR B CD1 1 
ATOM   5225 C CD2 . TYR B 1 274 ? 109.402 149.179 118.246 1.00 88.95  ? 274 TYR B CD2 1 
ATOM   5226 C CE1 . TYR B 1 274 ? 107.507 148.188 116.506 1.00 88.88  ? 274 TYR B CE1 1 
ATOM   5227 C CE2 . TYR B 1 274 ? 108.189 149.825 118.109 1.00 87.94  ? 274 TYR B CE2 1 
ATOM   5228 C CZ  . TYR B 1 274 ? 107.245 149.326 117.237 1.00 89.11  ? 274 TYR B CZ  1 
ATOM   5229 O OH  . TYR B 1 274 ? 106.035 149.966 117.097 1.00 85.93  ? 274 TYR B OH  1 
ATOM   5230 N N   . VAL B 1 275 ? 110.018 146.405 120.990 1.00 77.13  ? 275 VAL B N   1 
ATOM   5231 C CA  . VAL B 1 275 ? 109.157 145.522 121.767 1.00 79.62  ? 275 VAL B CA  1 
ATOM   5232 C C   . VAL B 1 275 ? 107.727 146.051 121.718 1.00 78.88  ? 275 VAL B C   1 
ATOM   5233 O O   . VAL B 1 275 ? 107.467 147.222 122.015 1.00 82.21  ? 275 VAL B O   1 
ATOM   5234 C CB  . VAL B 1 275 ? 109.674 145.350 123.208 1.00 75.83  ? 275 VAL B CB  1 
ATOM   5235 C CG1 . VAL B 1 275 ? 111.173 145.166 123.197 1.00 79.04  ? 275 VAL B CG1 1 
ATOM   5236 C CG2 . VAL B 1 275 ? 109.334 146.524 124.091 1.00 76.60  ? 275 VAL B CG2 1 
ATOM   5237 N N   . ARG B 1 276 ? 106.810 145.199 121.265 1.00 79.47  ? 276 ARG B N   1 
ATOM   5238 C CA  . ARG B 1 276 ? 105.375 145.476 121.252 1.00 79.30  ? 276 ARG B CA  1 
ATOM   5239 C C   . ARG B 1 276 ? 104.696 144.255 121.859 1.00 82.15  ? 276 ARG B C   1 
ATOM   5240 O O   . ARG B 1 276 ? 104.631 143.198 121.227 1.00 81.72  ? 276 ARG B O   1 
ATOM   5241 C CB  . ARG B 1 276 ? 104.861 145.749 119.841 1.00 80.83  ? 276 ARG B CB  1 
ATOM   5242 C CG  . ARG B 1 276 ? 105.496 146.934 119.128 1.00 82.30  ? 276 ARG B CG  1 
ATOM   5243 C CD  . ARG B 1 276 ? 105.431 148.222 119.952 1.00 84.69  ? 276 ARG B CD  1 
ATOM   5244 N NE  . ARG B 1 276 ? 104.154 148.462 120.621 1.00 89.08  ? 276 ARG B NE  1 
ATOM   5245 C CZ  . ARG B 1 276 ? 102.965 148.507 120.030 1.00 90.13  ? 276 ARG B CZ  1 
ATOM   5246 N NH1 . ARG B 1 276 ? 102.834 148.392 118.718 1.00 85.96  ? 276 ARG B NH1 1 
ATOM   5247 N NH2 . ARG B 1 276 ? 101.879 148.692 120.775 1.00 87.64  ? 276 ARG B NH2 1 
ATOM   5248 N N   . TRP B 1 277 ? 104.196 144.399 123.086 1.00 69.10  ? 277 TRP B N   1 
ATOM   5249 C CA  . TRP B 1 277 ? 103.634 143.250 123.785 1.00 64.32  ? 277 TRP B CA  1 
ATOM   5250 C C   . TRP B 1 277 ? 102.351 142.770 123.125 1.00 68.81  ? 277 TRP B C   1 
ATOM   5251 O O   . TRP B 1 277 ? 102.112 141.562 123.028 1.00 69.43  ? 277 TRP B O   1 
ATOM   5252 C CB  . TRP B 1 277 ? 103.390 143.601 125.250 1.00 61.03  ? 277 TRP B CB  1 
ATOM   5253 C CG  . TRP B 1 277 ? 104.656 143.786 126.007 1.00 61.01  ? 277 TRP B CG  1 
ATOM   5254 C CD1 . TRP B 1 277 ? 105.318 144.954 126.216 1.00 68.32  ? 277 TRP B CD1 1 
ATOM   5255 C CD2 . TRP B 1 277 ? 105.432 142.767 126.640 1.00 57.24  ? 277 TRP B CD2 1 
ATOM   5256 N NE1 . TRP B 1 277 ? 106.456 144.730 126.946 1.00 66.31  ? 277 TRP B NE1 1 
ATOM   5257 C CE2 . TRP B 1 277 ? 106.546 143.392 127.221 1.00 60.54  ? 277 TRP B CE2 1 
ATOM   5258 C CE3 . TRP B 1 277 ? 105.288 141.386 126.778 1.00 61.20  ? 277 TRP B CE3 1 
ATOM   5259 C CZ2 . TRP B 1 277 ? 107.510 142.688 127.924 1.00 57.85  ? 277 TRP B CZ2 1 
ATOM   5260 C CZ3 . TRP B 1 277 ? 106.243 140.690 127.478 1.00 63.90  ? 277 TRP B CZ3 1 
ATOM   5261 C CH2 . TRP B 1 277 ? 107.341 141.340 128.042 1.00 61.44  ? 277 TRP B CH2 1 
ATOM   5262 N N   . PHE B 1 278 ? 101.521 143.693 122.655 1.00 86.89  ? 278 PHE B N   1 
ATOM   5263 C CA  . PHE B 1 278 ? 100.189 143.372 122.161 1.00 83.33  ? 278 PHE B CA  1 
ATOM   5264 C C   . PHE B 1 278 ? 100.153 143.489 120.646 1.00 84.00  ? 278 PHE B C   1 
ATOM   5265 O O   . PHE B 1 278 ? 100.226 144.597 120.103 1.00 80.96  ? 278 PHE B O   1 
ATOM   5266 C CB  . PHE B 1 278 ? 99.148  144.292 122.788 1.00 82.34  ? 278 PHE B CB  1 
ATOM   5267 C CG  . PHE B 1 278 ? 98.919  144.031 124.240 1.00 81.56  ? 278 PHE B CG  1 
ATOM   5268 C CD1 . PHE B 1 278 ? 98.381  142.831 124.660 1.00 80.32  ? 278 PHE B CD1 1 
ATOM   5269 C CD2 . PHE B 1 278 ? 99.245  144.983 125.186 1.00 83.15  ? 278 PHE B CD2 1 
ATOM   5270 C CE1 . PHE B 1 278 ? 98.170  142.587 125.993 1.00 86.01  ? 278 PHE B CE1 1 
ATOM   5271 C CE2 . PHE B 1 278 ? 99.038  144.744 126.522 1.00 84.01  ? 278 PHE B CE2 1 
ATOM   5272 C CZ  . PHE B 1 278 ? 98.500  143.544 126.927 1.00 88.55  ? 278 PHE B CZ  1 
ATOM   5273 N N   . ASP B 1 279 ? 100.031 142.355 119.973 1.00 98.60  ? 279 ASP B N   1 
ATOM   5274 C CA  . ASP B 1 279 ? 99.786  142.360 118.543 1.00 101.74 ? 279 ASP B CA  1 
ATOM   5275 C C   . ASP B 1 279 ? 98.337  142.754 118.263 1.00 103.39 ? 279 ASP B C   1 
ATOM   5276 O O   . ASP B 1 279 ? 97.448  142.486 119.075 1.00 101.48 ? 279 ASP B O   1 
ATOM   5277 C CB  . ASP B 1 279 ? 100.071 140.986 117.949 1.00 99.37  ? 279 ASP B CB  1 
ATOM   5278 C CG  . ASP B 1 279 ? 101.367 140.949 117.169 1.00 99.84  ? 279 ASP B CG  1 
ATOM   5279 O OD1 . ASP B 1 279 ? 101.692 141.958 116.511 1.00 101.51 ? 279 ASP B OD1 1 
ATOM   5280 O OD2 . ASP B 1 279 ? 102.060 139.912 117.213 1.00 98.31  ? 279 ASP B OD2 1 
ATOM   5281 N N   . PRO B 1 280 ? 98.077  143.408 117.129 1.00 112.05 ? 280 PRO B N   1 
ATOM   5282 C CA  . PRO B 1 280 ? 96.686  143.752 116.794 1.00 110.40 ? 280 PRO B CA  1 
ATOM   5283 C C   . PRO B 1 280 ? 95.781  142.540 116.679 1.00 111.83 ? 280 PRO B C   1 
ATOM   5284 O O   . PRO B 1 280 ? 94.592  142.631 117.010 1.00 112.98 ? 280 PRO B O   1 
ATOM   5285 C CB  . PRO B 1 280 ? 96.822  144.489 115.455 1.00 110.22 ? 280 PRO B CB  1 
ATOM   5286 C CG  . PRO B 1 280 ? 98.224  145.004 115.450 1.00 111.89 ? 280 PRO B CG  1 
ATOM   5287 C CD  . PRO B 1 280 ? 99.034  143.961 116.158 1.00 111.91 ? 280 PRO B CD  1 
ATOM   5288 N N   . LYS B 1 281 ? 96.306  141.408 116.222 1.00 108.70 ? 281 LYS B N   1 
ATOM   5289 C CA  . LYS B 1 281 ? 95.557  140.161 116.116 1.00 109.77 ? 281 LYS B CA  1 
ATOM   5290 C C   . LYS B 1 281 ? 96.052  139.141 117.137 1.00 109.48 ? 281 LYS B C   1 
ATOM   5291 O O   . LYS B 1 281 ? 96.192  137.955 116.836 1.00 111.04 ? 281 LYS B O   1 
ATOM   5292 C CB  . LYS B 1 281 ? 95.649  139.587 114.704 1.00 109.29 ? 281 LYS B CB  1 
ATOM   5293 C CG  . LYS B 1 281 ? 95.132  140.503 113.602 1.00 109.89 ? 281 LYS B CG  1 
ATOM   5294 C CD  . LYS B 1 281 ? 93.896  141.278 114.030 1.00 108.48 ? 281 LYS B CD  1 
ATOM   5295 C CE  . LYS B 1 281 ? 93.480  142.275 112.960 1.00 108.18 ? 281 LYS B CE  1 
ATOM   5296 N NZ  . LYS B 1 281 ? 94.351  143.483 112.955 1.00 105.08 ? 281 LYS B NZ  1 
ATOM   5297 N N   . SER B 1 282 ? 96.335  139.604 118.353 1.00 100.88 ? 282 SER B N   1 
ATOM   5298 C CA  . SER B 1 282 ? 96.952  138.754 119.362 1.00 99.59  ? 282 SER B CA  1 
ATOM   5299 C C   . SER B 1 282 ? 96.053  137.576 119.713 1.00 98.49  ? 282 SER B C   1 
ATOM   5300 O O   . SER B 1 282 ? 94.838  137.723 119.867 1.00 97.93  ? 282 SER B O   1 
ATOM   5301 C CB  . SER B 1 282 ? 97.259  139.566 120.616 1.00 98.60  ? 282 SER B CB  1 
ATOM   5302 O OG  . SER B 1 282 ? 96.237  139.398 121.580 1.00 102.32 ? 282 SER B OG  1 
ATOM   5303 N N   . SER B 1 283 ? 96.663  136.403 119.838 1.00 89.91  ? 283 SER B N   1 
ATOM   5304 C CA  . SER B 1 283 ? 95.951  135.177 120.154 1.00 92.29  ? 283 SER B CA  1 
ATOM   5305 C C   . SER B 1 283 ? 95.769  135.035 121.662 1.00 89.55  ? 283 SER B C   1 
ATOM   5306 O O   . SER B 1 283 ? 96.393  135.735 122.458 1.00 90.08  ? 283 SER B O   1 
ATOM   5307 C CB  . SER B 1 283 ? 96.697  133.971 119.587 1.00 91.78  ? 283 SER B CB  1 
ATOM   5308 O OG  . SER B 1 283 ? 98.068  134.009 119.941 1.00 88.82  ? 283 SER B OG  1 
ATOM   5309 N N   . PHE B 1 284 ? 94.897  134.102 122.052 1.00 93.59  ? 284 PHE B N   1 
ATOM   5310 C CA  . PHE B 1 284 ? 94.637  133.888 123.471 1.00 92.24  ? 284 PHE B CA  1 
ATOM   5311 C C   . PHE B 1 284 ? 95.890  133.450 124.214 1.00 89.91  ? 284 PHE B C   1 
ATOM   5312 O O   . PHE B 1 284 ? 96.030  133.726 125.410 1.00 92.92  ? 284 PHE B O   1 
ATOM   5313 C CB  . PHE B 1 284 ? 93.526  132.853 123.657 1.00 92.99  ? 284 PHE B CB  1 
ATOM   5314 C CG  . PHE B 1 284 ? 92.142  133.423 123.540 1.00 96.45  ? 284 PHE B CG  1 
ATOM   5315 C CD1 . PHE B 1 284 ? 91.940  134.792 123.533 1.00 95.60  ? 284 PHE B CD1 1 
ATOM   5316 C CD2 . PHE B 1 284 ? 91.043  132.588 123.435 1.00 95.16  ? 284 PHE B CD2 1 
ATOM   5317 C CE1 . PHE B 1 284 ? 90.668  135.317 123.425 1.00 95.22  ? 284 PHE B CE1 1 
ATOM   5318 C CE2 . PHE B 1 284 ? 89.767  133.108 123.326 1.00 94.15  ? 284 PHE B CE2 1 
ATOM   5319 C CZ  . PHE B 1 284 ? 89.580  134.474 123.321 1.00 94.36  ? 284 PHE B CZ  1 
ATOM   5320 N N   . GLN B 1 285 ? 96.807  132.763 123.533 1.00 83.05  ? 285 GLN B N   1 
ATOM   5321 C CA  . GLN B 1 285 ? 98.062  132.386 124.173 1.00 81.49  ? 285 GLN B CA  1 
ATOM   5322 C C   . GLN B 1 285 ? 98.916  133.612 124.470 1.00 82.08  ? 285 GLN B C   1 
ATOM   5323 O O   . GLN B 1 285 ? 99.630  133.647 125.477 1.00 90.13  ? 285 GLN B O   1 
ATOM   5324 C CB  . GLN B 1 285 ? 98.824  131.400 123.292 1.00 86.15  ? 285 GLN B CB  1 
ATOM   5325 C CG  . GLN B 1 285 ? 97.976  130.255 122.772 1.00 88.15  ? 285 GLN B CG  1 
ATOM   5326 C CD  . GLN B 1 285 ? 98.019  129.041 123.674 1.00 91.66  ? 285 GLN B CD  1 
ATOM   5327 O OE1 . GLN B 1 285 ? 98.115  129.163 124.894 1.00 90.65  ? 285 GLN B OE1 1 
ATOM   5328 N NE2 . GLN B 1 285 ? 97.944  127.858 123.076 1.00 91.12  ? 285 GLN B NE2 1 
ATOM   5329 N N   . ARG B 1 286 ? 98.862  134.623 123.604 1.00 76.89  ? 286 ARG B N   1 
ATOM   5330 C CA  . ARG B 1 286 ? 99.646  135.831 123.830 1.00 76.35  ? 286 ARG B CA  1 
ATOM   5331 C C   . ARG B 1 286 ? 99.051  136.694 124.937 1.00 74.30  ? 286 ARG B C   1 
ATOM   5332 O O   . ARG B 1 286 ? 99.792  137.245 125.756 1.00 77.68  ? 286 ARG B O   1 
ATOM   5333 C CB  . ARG B 1 286 ? 99.764  136.632 122.535 1.00 78.25  ? 286 ARG B CB  1 
ATOM   5334 C CG  . ARG B 1 286 ? 100.278 138.042 122.730 1.00 73.57  ? 286 ARG B CG  1 
ATOM   5335 C CD  . ARG B 1 286 ? 101.791 138.064 122.719 1.00 73.68  ? 286 ARG B CD  1 
ATOM   5336 N NE  . ARG B 1 286 ? 102.335 137.832 121.388 1.00 77.31  ? 286 ARG B NE  1 
ATOM   5337 C CZ  . ARG B 1 286 ? 102.857 138.779 120.623 1.00 79.30  ? 286 ARG B CZ  1 
ATOM   5338 N NH1 . ARG B 1 286 ? 102.924 140.035 121.029 1.00 77.05  ? 286 ARG B NH1 1 
ATOM   5339 N NH2 . ARG B 1 286 ? 103.327 138.457 119.422 1.00 78.91  ? 286 ARG B NH2 1 
ATOM   5340 N N   . VAL B 1 287 ? 97.724  136.830 124.981 1.00 70.34  ? 287 VAL B N   1 
ATOM   5341 C CA  . VAL B 1 287 ? 97.105  137.609 126.050 1.00 66.67  ? 287 VAL B CA  1 
ATOM   5342 C C   . VAL B 1 287 ? 97.364  136.956 127.398 1.00 65.44  ? 287 VAL B C   1 
ATOM   5343 O O   . VAL B 1 287 ? 97.708  137.629 128.375 1.00 72.73  ? 287 VAL B O   1 
ATOM   5344 C CB  . VAL B 1 287 ? 95.599  137.789 125.794 1.00 72.76  ? 287 VAL B CB  1 
ATOM   5345 C CG1 . VAL B 1 287 ? 95.066  138.951 126.609 1.00 73.58  ? 287 VAL B CG1 1 
ATOM   5346 C CG2 . VAL B 1 287 ? 95.337  138.023 124.327 1.00 70.62  ? 287 VAL B CG2 1 
ATOM   5347 N N   . ALA B 1 288 ? 97.204  135.635 127.476 1.00 65.20  ? 288 ALA B N   1 
ATOM   5348 C CA  . ALA B 1 288 ? 97.523  134.931 128.710 1.00 67.69  ? 288 ALA B CA  1 
ATOM   5349 C C   . ALA B 1 288 ? 99.016  134.927 128.994 1.00 68.12  ? 288 ALA B C   1 
ATOM   5350 O O   . ALA B 1 288 ? 99.413  134.772 130.152 1.00 73.85  ? 288 ALA B O   1 
ATOM   5351 C CB  . ALA B 1 288 ? 96.998  133.498 128.654 1.00 66.89  ? 288 ALA B CB  1 
ATOM   5352 N N   . GLY B 1 289 ? 99.851  135.076 127.968 1.00 61.10  ? 289 GLY B N   1 
ATOM   5353 C CA  . GLY B 1 289 ? 101.275 135.227 128.211 1.00 60.56  ? 289 GLY B CA  1 
ATOM   5354 C C   . GLY B 1 289 ? 101.611 136.532 128.905 1.00 64.55  ? 289 GLY B C   1 
ATOM   5355 O O   . GLY B 1 289 ? 102.426 136.560 129.828 1.00 69.94  ? 289 GLY B O   1 
ATOM   5356 N N   . VAL B 1 290 ? 100.998 137.632 128.463 1.00 64.06  ? 290 VAL B N   1 
ATOM   5357 C CA  . VAL B 1 290 ? 101.233 138.916 129.111 1.00 57.48  ? 290 VAL B CA  1 
ATOM   5358 C C   . VAL B 1 290 ? 100.584 138.948 130.485 1.00 64.42  ? 290 VAL B C   1 
ATOM   5359 O O   . VAL B 1 290 ? 101.095 139.598 131.403 1.00 77.32  ? 290 VAL B O   1 
ATOM   5360 C CB  . VAL B 1 290 ? 100.732 140.070 128.225 1.00 56.96  ? 290 VAL B CB  1 
ATOM   5361 C CG1 . VAL B 1 290 ? 101.152 141.398 128.805 1.00 59.98  ? 290 VAL B CG1 1 
ATOM   5362 C CG2 . VAL B 1 290 ? 101.274 139.928 126.825 1.00 62.43  ? 290 VAL B CG2 1 
ATOM   5363 N N   . TYR B 1 291 ? 99.455  138.257 130.656 1.00 61.66  ? 291 TYR B N   1 
ATOM   5364 C CA  . TYR B 1 291 ? 98.789  138.247 131.955 1.00 57.05  ? 291 TYR B CA  1 
ATOM   5365 C C   . TYR B 1 291 ? 99.669  137.618 133.021 1.00 52.46  ? 291 TYR B C   1 
ATOM   5366 O O   . TYR B 1 291 ? 99.691  138.078 134.167 1.00 57.54  ? 291 TYR B O   1 
ATOM   5367 C CB  . TYR B 1 291 ? 97.461  137.505 131.873 1.00 56.33  ? 291 TYR B CB  1 
ATOM   5368 C CG  . TYR B 1 291 ? 96.641  137.648 133.126 1.00 54.67  ? 291 TYR B CG  1 
ATOM   5369 C CD1 . TYR B 1 291 ? 96.445  138.888 133.704 1.00 59.31  ? 291 TYR B CD1 1 
ATOM   5370 C CD2 . TYR B 1 291 ? 96.074  136.547 133.738 1.00 62.26  ? 291 TYR B CD2 1 
ATOM   5371 C CE1 . TYR B 1 291 ? 95.702  139.030 134.849 1.00 59.63  ? 291 TYR B CE1 1 
ATOM   5372 C CE2 . TYR B 1 291 ? 95.329  136.678 134.885 1.00 63.34  ? 291 TYR B CE2 1 
ATOM   5373 C CZ  . TYR B 1 291 ? 95.146  137.924 135.436 1.00 62.93  ? 291 TYR B CZ  1 
ATOM   5374 O OH  . TYR B 1 291 ? 94.404  138.065 136.582 1.00 72.14  ? 291 TYR B OH  1 
ATOM   5375 N N   . LEU B 1 292 ? 100.388 136.554 132.671 1.00 54.44  ? 292 LEU B N   1 
ATOM   5376 C CA  . LEU B 1 292 ? 101.325 135.964 133.616 1.00 55.04  ? 292 LEU B CA  1 
ATOM   5377 C C   . LEU B 1 292 ? 102.477 136.908 133.920 1.00 54.65  ? 292 LEU B C   1 
ATOM   5378 O O   . LEU B 1 292 ? 102.957 136.950 135.055 1.00 64.93  ? 292 LEU B O   1 
ATOM   5379 C CB  . LEU B 1 292 ? 101.848 134.638 133.073 1.00 60.52  ? 292 LEU B CB  1 
ATOM   5380 C CG  . LEU B 1 292 ? 102.810 133.894 133.989 1.00 57.15  ? 292 LEU B CG  1 
ATOM   5381 C CD1 . LEU B 1 292 ? 102.080 133.432 135.227 1.00 62.13  ? 292 LEU B CD1 1 
ATOM   5382 C CD2 . LEU B 1 292 ? 103.424 132.720 133.261 1.00 55.58  ? 292 LEU B CD2 1 
ATOM   5383 N N   . PHE B 1 293 ? 102.933 137.671 132.927 1.00 47.12  ? 293 PHE B N   1 
ATOM   5384 C CA  . PHE B 1 293 ? 103.980 138.656 133.172 1.00 46.07  ? 293 PHE B CA  1 
ATOM   5385 C C   . PHE B 1 293 ? 103.513 139.712 134.160 1.00 54.79  ? 293 PHE B C   1 
ATOM   5386 O O   . PHE B 1 293 ? 104.274 140.135 135.035 1.00 66.88  ? 293 PHE B O   1 
ATOM   5387 C CB  . PHE B 1 293 ? 104.397 139.311 131.861 1.00 54.40  ? 293 PHE B CB  1 
ATOM   5388 C CG  . PHE B 1 293 ? 105.523 140.287 131.999 1.00 54.97  ? 293 PHE B CG  1 
ATOM   5389 C CD1 . PHE B 1 293 ? 106.808 139.850 132.248 1.00 55.32  ? 293 PHE B CD1 1 
ATOM   5390 C CD2 . PHE B 1 293 ? 105.298 141.641 131.872 1.00 48.89  ? 293 PHE B CD2 1 
ATOM   5391 C CE1 . PHE B 1 293 ? 107.841 140.744 132.364 1.00 52.05  ? 293 PHE B CE1 1 
ATOM   5392 C CE2 . PHE B 1 293 ? 106.329 142.535 131.990 1.00 49.64  ? 293 PHE B CE2 1 
ATOM   5393 C CZ  . PHE B 1 293 ? 107.601 142.084 132.238 1.00 53.22  ? 293 PHE B CZ  1 
ATOM   5394 N N   . MET B 1 294 ? 102.266 140.157 134.028 1.00 55.20  ? 294 MET B N   1 
ATOM   5395 C CA  . MET B 1 294 ? 101.728 141.143 134.955 1.00 51.68  ? 294 MET B CA  1 
ATOM   5396 C C   . MET B 1 294 ? 101.586 140.562 136.356 1.00 53.17  ? 294 MET B C   1 
ATOM   5397 O O   . MET B 1 294 ? 101.803 141.265 137.349 1.00 52.35  ? 294 MET B O   1 
ATOM   5398 C CB  . MET B 1 294 ? 100.382 141.647 134.439 1.00 56.63  ? 294 MET B CB  1 
ATOM   5399 C CG  . MET B 1 294 ? 100.454 142.323 133.083 1.00 55.79  ? 294 MET B CG  1 
ATOM   5400 S SD  . MET B 1 294 ? 99.013  143.341 132.730 1.00 68.04  ? 294 MET B SD  1 
ATOM   5401 C CE  . MET B 1 294 ? 99.288  144.724 133.820 1.00 58.24  ? 294 MET B CE  1 
ATOM   5402 N N   . ILE B 1 295 ? 101.216 139.285 136.458 1.00 56.38  ? 295 ILE B N   1 
ATOM   5403 C CA  . ILE B 1 295 ? 101.013 138.666 137.765 1.00 48.51  ? 295 ILE B CA  1 
ATOM   5404 C C   . ILE B 1 295 ? 102.343 138.479 138.486 1.00 48.78  ? 295 ILE B C   1 
ATOM   5405 O O   . ILE B 1 295 ? 102.477 138.819 139.666 1.00 57.30  ? 295 ILE B O   1 
ATOM   5406 C CB  . ILE B 1 295 ? 100.265 137.332 137.614 1.00 43.97  ? 295 ILE B CB  1 
ATOM   5407 C CG1 . ILE B 1 295 ? 98.786  137.588 137.361 1.00 48.48  ? 295 ILE B CG1 1 
ATOM   5408 C CG2 . ILE B 1 295 ? 100.434 136.490 138.853 1.00 49.79  ? 295 ILE B CG2 1 
ATOM   5409 C CD1 . ILE B 1 295 ? 98.144  138.422 138.413 1.00 48.62  ? 295 ILE B CD1 1 
ATOM   5410 N N   . ILE B 1 296 ? 103.346 137.938 137.792 1.00 47.87  ? 296 ILE B N   1 
ATOM   5411 C CA  . ILE B 1 296 ? 104.638 137.713 138.430 1.00 44.44  ? 296 ILE B CA  1 
ATOM   5412 C C   . ILE B 1 296 ? 105.280 139.034 138.824 1.00 55.00  ? 296 ILE B C   1 
ATOM   5413 O O   . ILE B 1 296 ? 106.024 139.102 139.807 1.00 69.69  ? 296 ILE B O   1 
ATOM   5414 C CB  . ILE B 1 296 ? 105.563 136.892 137.516 1.00 49.26  ? 296 ILE B CB  1 
ATOM   5415 C CG1 . ILE B 1 296 ? 104.878 135.601 137.083 1.00 53.31  ? 296 ILE B CG1 1 
ATOM   5416 C CG2 . ILE B 1 296 ? 106.855 136.557 138.230 1.00 57.92  ? 296 ILE B CG2 1 
ATOM   5417 C CD1 . ILE B 1 296 ? 104.345 134.799 138.224 1.00 57.38  ? 296 ILE B CD1 1 
ATOM   5418 N N   . TRP B 1 297 ? 105.009 140.102 138.075 1.00 51.91  ? 297 TRP B N   1 
ATOM   5419 C CA  . TRP B 1 297 ? 105.520 141.416 138.447 1.00 48.98  ? 297 TRP B CA  1 
ATOM   5420 C C   . TRP B 1 297 ? 104.976 141.859 139.798 1.00 56.49  ? 297 TRP B C   1 
ATOM   5421 O O   . TRP B 1 297 ? 105.721 142.382 140.632 1.00 65.21  ? 297 TRP B O   1 
ATOM   5422 C CB  . TRP B 1 297 ? 105.190 142.427 137.353 1.00 52.04  ? 297 TRP B CB  1 
ATOM   5423 C CG  . TRP B 1 297 ? 105.971 143.693 137.436 1.00 55.05  ? 297 TRP B CG  1 
ATOM   5424 C CD1 . TRP B 1 297 ? 106.767 144.097 138.460 1.00 58.42  ? 297 TRP B CD1 1 
ATOM   5425 C CD2 . TRP B 1 297 ? 106.060 144.709 136.435 1.00 55.36  ? 297 TRP B CD2 1 
ATOM   5426 N NE1 . TRP B 1 297 ? 107.325 145.315 138.175 1.00 59.89  ? 297 TRP B NE1 1 
ATOM   5427 C CE2 . TRP B 1 297 ? 106.909 145.709 136.932 1.00 63.45  ? 297 TRP B CE2 1 
ATOM   5428 C CE3 . TRP B 1 297 ? 105.506 144.867 135.166 1.00 51.85  ? 297 TRP B CE3 1 
ATOM   5429 C CZ2 . TRP B 1 297 ? 107.209 146.857 136.208 1.00 69.99  ? 297 TRP B CZ2 1 
ATOM   5430 C CZ3 . TRP B 1 297 ? 105.792 146.008 134.456 1.00 56.66  ? 297 TRP B CZ3 1 
ATOM   5431 C CH2 . TRP B 1 297 ? 106.641 146.986 134.973 1.00 64.68  ? 297 TRP B CH2 1 
ATOM   5432 N N   . GLN B 1 298 ? 103.679 141.656 140.039 1.00 54.00  ? 298 GLN B N   1 
ATOM   5433 C CA  . GLN B 1 298 ? 103.133 141.962 141.358 1.00 48.27  ? 298 GLN B CA  1 
ATOM   5434 C C   . GLN B 1 298 ? 103.738 141.069 142.426 1.00 58.57  ? 298 GLN B C   1 
ATOM   5435 O O   . GLN B 1 298 ? 103.993 141.517 143.548 1.00 70.38  ? 298 GLN B O   1 
ATOM   5436 C CB  . GLN B 1 298 ? 101.618 141.816 141.367 1.00 49.78  ? 298 GLN B CB  1 
ATOM   5437 C CG  . GLN B 1 298 ? 100.881 143.105 141.167 1.00 54.12  ? 298 GLN B CG  1 
ATOM   5438 C CD  . GLN B 1 298 ? 100.311 143.228 139.785 1.00 64.44  ? 298 GLN B CD  1 
ATOM   5439 O OE1 . GLN B 1 298 ? 99.655  142.317 139.285 1.00 64.38  ? 298 GLN B OE1 1 
ATOM   5440 N NE2 . GLN B 1 298 ? 100.533 144.368 139.165 1.00 70.53  ? 298 GLN B NE2 1 
ATOM   5441 N N   . LEU B 1 299 ? 103.968 139.799 142.098 1.00 48.85  ? 299 LEU B N   1 
ATOM   5442 C CA  . LEU B 1 299 ? 104.500 138.870 143.086 1.00 39.28  ? 299 LEU B CA  1 
ATOM   5443 C C   . LEU B 1 299 ? 105.856 139.332 143.595 1.00 45.01  ? 299 LEU B C   1 
ATOM   5444 O O   . LEU B 1 299 ? 106.129 139.264 144.797 1.00 64.39  ? 299 LEU B O   1 
ATOM   5445 C CB  . LEU B 1 299 ? 104.596 137.473 142.483 1.00 48.89  ? 299 LEU B CB  1 
ATOM   5446 C CG  . LEU B 1 299 ? 104.653 136.314 143.467 1.00 48.19  ? 299 LEU B CG  1 
ATOM   5447 C CD1 . LEU B 1 299 ? 103.351 136.229 144.223 1.00 52.08  ? 299 LEU B CD1 1 
ATOM   5448 C CD2 . LEU B 1 299 ? 104.922 135.028 142.727 1.00 49.41  ? 299 LEU B CD2 1 
ATOM   5449 N N   . THR B 1 300 ? 106.720 139.814 142.701 1.00 43.73  ? 300 THR B N   1 
ATOM   5450 C CA  . THR B 1 300 ? 107.998 140.361 143.143 1.00 51.61  ? 300 THR B CA  1 
ATOM   5451 C C   . THR B 1 300 ? 107.800 141.614 143.985 1.00 55.24  ? 300 THR B C   1 
ATOM   5452 O O   . THR B 1 300 ? 108.526 141.836 144.958 1.00 62.99  ? 300 THR B O   1 
ATOM   5453 C CB  . THR B 1 300 ? 108.892 140.660 141.944 1.00 57.88  ? 300 THR B CB  1 
ATOM   5454 O OG1 . THR B 1 300 ? 108.350 141.759 141.206 1.00 61.34  ? 300 THR B OG1 1 
ATOM   5455 C CG2 . THR B 1 300 ? 108.984 139.448 141.044 1.00 56.97  ? 300 THR B CG2 1 
ATOM   5456 N N   . GLU B 1 301 ? 106.835 142.458 143.614 1.00 52.87  ? 301 GLU B N   1 
ATOM   5457 C CA  . GLU B 1 301 ? 106.494 143.599 144.457 1.00 55.23  ? 301 GLU B CA  1 
ATOM   5458 C C   . GLU B 1 301 ? 105.902 143.144 145.783 1.00 55.04  ? 301 GLU B C   1 
ATOM   5459 O O   . GLU B 1 301 ? 106.168 143.744 146.829 1.00 54.63  ? 301 GLU B O   1 
ATOM   5460 C CB  . GLU B 1 301 ? 105.520 144.522 143.728 1.00 53.06  ? 301 GLU B CB  1 
ATOM   5461 C CG  . GLU B 1 301 ? 106.048 145.077 142.424 1.00 61.83  ? 301 GLU B CG  1 
ATOM   5462 C CD  . GLU B 1 301 ? 106.658 146.452 142.581 1.00 67.82  ? 301 GLU B CD  1 
ATOM   5463 O OE1 . GLU B 1 301 ? 107.172 146.754 143.678 1.00 70.34  ? 301 GLU B OE1 1 
ATOM   5464 O OE2 . GLU B 1 301 ? 106.624 147.232 141.607 1.00 63.81  ? 301 GLU B OE2 1 
ATOM   5465 N N   . LEU B 1 302 ? 105.083 142.093 145.754 1.00 56.09  ? 302 LEU B N   1 
ATOM   5466 C CA  . LEU B 1 302 ? 104.488 141.575 146.981 1.00 50.74  ? 302 LEU B CA  1 
ATOM   5467 C C   . LEU B 1 302 ? 105.538 140.909 147.861 1.00 50.80  ? 302 LEU B C   1 
ATOM   5468 O O   . LEU B 1 302 ? 105.486 141.005 149.091 1.00 60.10  ? 302 LEU B O   1 
ATOM   5469 C CB  . LEU B 1 302 ? 103.370 140.595 146.637 1.00 47.25  ? 302 LEU B CB  1 
ATOM   5470 C CG  . LEU B 1 302 ? 102.267 140.401 147.667 1.00 46.06  ? 302 LEU B CG  1 
ATOM   5471 C CD1 . LEU B 1 302 ? 101.348 141.602 147.662 1.00 55.02  ? 302 LEU B CD1 1 
ATOM   5472 C CD2 . LEU B 1 302 ? 101.494 139.145 147.355 1.00 53.39  ? 302 LEU B CD2 1 
ATOM   5473 N N   . ASN B 1 303 ? 106.497 140.217 147.245 1.00 46.90  ? 303 ASN B N   1 
ATOM   5474 C CA  . ASN B 1 303 ? 107.571 139.588 148.005 1.00 38.85  ? 303 ASN B CA  1 
ATOM   5475 C C   . ASN B 1 303 ? 108.393 140.624 148.754 1.00 56.17  ? 303 ASN B C   1 
ATOM   5476 O O   . ASN B 1 303 ? 108.723 140.440 149.928 1.00 66.89  ? 303 ASN B O   1 
ATOM   5477 C CB  . ASN B 1 303 ? 108.465 138.777 147.071 1.00 41.20  ? 303 ASN B CB  1 
ATOM   5478 C CG  . ASN B 1 303 ? 107.804 137.510 146.589 1.00 59.37  ? 303 ASN B CG  1 
ATOM   5479 O OD1 . ASN B 1 303 ? 106.765 137.104 147.104 1.00 61.41  ? 303 ASN B OD1 1 
ATOM   5480 N ND2 . ASN B 1 303 ? 108.394 136.884 145.581 1.00 64.93  ? 303 ASN B ND2 1 
ATOM   5481 N N   . THR B 1 304 ? 108.730 141.727 148.086 1.00 61.87  ? 304 THR B N   1 
ATOM   5482 C CA  . THR B 1 304 ? 109.564 142.754 148.702 1.00 53.95  ? 304 THR B CA  1 
ATOM   5483 C C   . THR B 1 304 ? 108.887 143.355 149.925 1.00 53.14  ? 304 THR B C   1 
ATOM   5484 O O   . THR B 1 304 ? 109.525 143.571 150.960 1.00 62.33  ? 304 THR B O   1 
ATOM   5485 C CB  . THR B 1 304 ? 109.883 143.843 147.680 1.00 56.57  ? 304 THR B CB  1 
ATOM   5486 O OG1 . THR B 1 304 ? 110.884 143.372 146.772 1.00 62.96  ? 304 THR B OG1 1 
ATOM   5487 C CG2 . THR B 1 304 ? 110.383 145.091 148.374 1.00 60.18  ? 304 THR B CG2 1 
ATOM   5488 N N   . PHE B 1 305 ? 107.589 143.631 149.822 1.00 53.73  ? 305 PHE B N   1 
ATOM   5489 C CA  . PHE B 1 305 ? 106.869 144.235 150.936 1.00 51.14  ? 305 PHE B CA  1 
ATOM   5490 C C   . PHE B 1 305 ? 106.802 143.295 152.130 1.00 55.58  ? 305 PHE B C   1 
ATOM   5491 O O   . PHE B 1 305 ? 106.937 143.725 153.279 1.00 68.57  ? 305 PHE B O   1 
ATOM   5492 C CB  . PHE B 1 305 ? 105.462 144.629 150.498 1.00 56.54  ? 305 PHE B CB  1 
ATOM   5493 C CG  . PHE B 1 305 ? 104.600 145.123 151.618 1.00 66.22  ? 305 PHE B CG  1 
ATOM   5494 C CD1 . PHE B 1 305 ? 104.823 146.363 152.183 1.00 68.76  ? 305 PHE B CD1 1 
ATOM   5495 C CD2 . PHE B 1 305 ? 103.577 144.342 152.118 1.00 63.27  ? 305 PHE B CD2 1 
ATOM   5496 C CE1 . PHE B 1 305 ? 104.034 146.817 153.216 1.00 64.48  ? 305 PHE B CE1 1 
ATOM   5497 C CE2 . PHE B 1 305 ? 102.790 144.792 153.151 1.00 61.59  ? 305 PHE B CE2 1 
ATOM   5498 C CZ  . PHE B 1 305 ? 103.018 146.029 153.700 1.00 61.71  ? 305 PHE B CZ  1 
ATOM   5499 N N   . PHE B 1 306 ? 106.587 142.004 151.881 1.00 57.91  ? 306 PHE B N   1 
ATOM   5500 C CA  . PHE B 1 306 ? 106.282 141.090 152.975 1.00 61.20  ? 306 PHE B CA  1 
ATOM   5501 C C   . PHE B 1 306 ? 107.536 140.664 153.726 1.00 64.10  ? 306 PHE B C   1 
ATOM   5502 O O   . PHE B 1 306 ? 107.563 140.687 154.960 1.00 76.07  ? 306 PHE B O   1 
ATOM   5503 C CB  . PHE B 1 306 ? 105.526 139.876 152.448 1.00 62.27  ? 306 PHE B CB  1 
ATOM   5504 C CG  . PHE B 1 306 ? 104.048 139.972 152.637 1.00 61.86  ? 306 PHE B CG  1 
ATOM   5505 C CD1 . PHE B 1 306 ? 103.526 140.395 153.840 1.00 61.72  ? 306 PHE B CD1 1 
ATOM   5506 C CD2 . PHE B 1 306 ? 103.182 139.660 151.609 1.00 64.95  ? 306 PHE B CD2 1 
ATOM   5507 C CE1 . PHE B 1 306 ? 102.174 140.492 154.020 1.00 66.18  ? 306 PHE B CE1 1 
ATOM   5508 C CE2 . PHE B 1 306 ? 101.826 139.758 151.785 1.00 65.73  ? 306 PHE B CE2 1 
ATOM   5509 C CZ  . PHE B 1 306 ? 101.321 140.175 152.993 1.00 68.62  ? 306 PHE B CZ  1 
ATOM   5510 N N   . LEU B 1 307 ? 108.587 140.267 153.006 1.00 55.50  ? 307 LEU B N   1 
ATOM   5511 C CA  . LEU B 1 307 ? 109.775 139.773 153.698 1.00 65.39  ? 307 LEU B CA  1 
ATOM   5512 C C   . LEU B 1 307 ? 110.423 140.870 154.533 1.00 70.02  ? 307 LEU B C   1 
ATOM   5513 O O   . LEU B 1 307 ? 111.085 140.585 155.536 1.00 71.91  ? 307 LEU B O   1 
ATOM   5514 C CB  . LEU B 1 307 ? 110.775 139.173 152.711 1.00 55.89  ? 307 LEU B CB  1 
ATOM   5515 C CG  . LEU B 1 307 ? 111.325 139.988 151.548 1.00 66.73  ? 307 LEU B CG  1 
ATOM   5516 C CD1 . LEU B 1 307 ? 112.533 140.806 151.963 1.00 73.16  ? 307 LEU B CD1 1 
ATOM   5517 C CD2 . LEU B 1 307 ? 111.693 139.045 150.423 1.00 64.77  ? 307 LEU B CD2 1 
ATOM   5518 N N   . LYS B 1 308 ? 110.253 142.130 154.133 1.00 70.31  ? 308 LYS B N   1 
ATOM   5519 C CA  . LYS B 1 308 ? 110.627 143.227 155.018 1.00 68.32  ? 308 LYS B CA  1 
ATOM   5520 C C   . LYS B 1 308 ? 109.755 143.236 156.263 1.00 68.94  ? 308 LYS B C   1 
ATOM   5521 O O   . LYS B 1 308 ? 110.243 143.468 157.375 1.00 70.70  ? 308 LYS B O   1 
ATOM   5522 C CB  . LYS B 1 308 ? 110.509 144.563 154.288 1.00 66.73  ? 308 LYS B CB  1 
ATOM   5523 C CG  . LYS B 1 308 ? 111.833 145.225 153.967 1.00 70.27  ? 308 LYS B CG  1 
ATOM   5524 C CD  . LYS B 1 308 ? 111.654 146.362 152.975 1.00 72.23  ? 308 LYS B CD  1 
ATOM   5525 C CE  . LYS B 1 308 ? 110.308 147.053 153.155 1.00 74.20  ? 308 LYS B CE  1 
ATOM   5526 N NZ  . LYS B 1 308 ? 110.021 148.015 152.057 1.00 74.36  ? 308 LYS B NZ  1 
ATOM   5527 N N   . HIS B 1 309 ? 108.458 142.988 156.094 1.00 70.17  ? 309 HIS B N   1 
ATOM   5528 C CA  . HIS B 1 309 ? 107.530 143.054 157.215 1.00 70.36  ? 309 HIS B CA  1 
ATOM   5529 C C   . HIS B 1 309 ? 107.688 141.853 158.137 1.00 75.07  ? 309 HIS B C   1 
ATOM   5530 O O   . HIS B 1 309 ? 107.518 141.973 159.355 1.00 82.68  ? 309 HIS B O   1 
ATOM   5531 C CB  . HIS B 1 309 ? 106.100 143.149 156.689 1.00 71.65  ? 309 HIS B CB  1 
ATOM   5532 C CG  . HIS B 1 309 ? 105.091 143.502 157.732 1.00 79.67  ? 309 HIS B CG  1 
ATOM   5533 N ND1 . HIS B 1 309 ? 104.809 142.684 158.804 1.00 82.20  ? 309 HIS B ND1 1 
ATOM   5534 C CD2 . HIS B 1 309 ? 104.290 144.586 157.865 1.00 83.99  ? 309 HIS B CD2 1 
ATOM   5535 C CE1 . HIS B 1 309 ? 103.881 143.251 159.555 1.00 82.19  ? 309 HIS B CE1 1 
ATOM   5536 N NE2 . HIS B 1 309 ? 103.549 144.405 159.007 1.00 85.65  ? 309 HIS B NE2 1 
ATOM   5537 N N   . ILE B 1 310 ? 108.013 140.691 157.577 1.00 66.99  ? 310 ILE B N   1 
ATOM   5538 C CA  . ILE B 1 310 ? 108.093 139.446 158.333 1.00 65.57  ? 310 ILE B CA  1 
ATOM   5539 C C   . ILE B 1 310 ? 109.401 139.392 159.108 1.00 68.47  ? 310 ILE B C   1 
ATOM   5540 O O   . ILE B 1 310 ? 109.405 139.317 160.341 1.00 69.16  ? 310 ILE B O   1 
ATOM   5541 C CB  . ILE B 1 310 ? 107.959 138.237 157.395 1.00 61.39  ? 310 ILE B CB  1 
ATOM   5542 C CG1 . ILE B 1 310 ? 106.560 138.205 156.793 1.00 66.89  ? 310 ILE B CG1 1 
ATOM   5543 C CG2 . ILE B 1 310 ? 108.231 136.956 158.142 1.00 68.03  ? 310 ILE B CG2 1 
ATOM   5544 C CD1 . ILE B 1 310 ? 106.288 136.975 156.002 1.00 69.70  ? 310 ILE B CD1 1 
ATOM   5545 N N   . PHE B 1 311 ? 110.519 139.417 158.389 1.00 73.40  ? 311 PHE B N   1 
ATOM   5546 C CA  . PHE B 1 311 ? 111.838 139.545 159.002 1.00 77.12  ? 311 PHE B CA  1 
ATOM   5547 C C   . PHE B 1 311 ? 112.118 141.031 159.163 1.00 77.01  ? 311 PHE B C   1 
ATOM   5548 O O   . PHE B 1 311 ? 112.496 141.710 158.209 1.00 78.20  ? 311 PHE B O   1 
ATOM   5549 C CB  . PHE B 1 311 ? 112.896 138.864 158.145 1.00 73.88  ? 311 PHE B CB  1 
ATOM   5550 C CG  . PHE B 1 311 ? 112.458 137.551 157.578 1.00 74.96  ? 311 PHE B CG  1 
ATOM   5551 C CD1 . PHE B 1 311 ? 112.211 136.474 158.407 1.00 78.57  ? 311 PHE B CD1 1 
ATOM   5552 C CD2 . PHE B 1 311 ? 112.276 137.396 156.217 1.00 72.63  ? 311 PHE B CD2 1 
ATOM   5553 C CE1 . PHE B 1 311 ? 111.803 135.266 157.888 1.00 78.10  ? 311 PHE B CE1 1 
ATOM   5554 C CE2 . PHE B 1 311 ? 111.864 136.190 155.693 1.00 73.96  ? 311 PHE B CE2 1 
ATOM   5555 C CZ  . PHE B 1 311 ? 111.628 135.124 156.529 1.00 74.29  ? 311 PHE B CZ  1 
ATOM   5556 N N   . VAL B 1 312 ? 111.931 141.542 160.376 1.00 78.21  ? 312 VAL B N   1 
ATOM   5557 C CA  . VAL B 1 312 ? 111.933 142.981 160.605 1.00 79.67  ? 312 VAL B CA  1 
ATOM   5558 C C   . VAL B 1 312 ? 113.321 143.565 160.386 1.00 83.23  ? 312 VAL B C   1 
ATOM   5559 O O   . VAL B 1 312 ? 114.230 143.357 161.196 1.00 86.43  ? 312 VAL B O   1 
ATOM   5560 C CB  . VAL B 1 312 ? 111.425 143.314 162.017 1.00 78.70  ? 312 VAL B CB  1 
ATOM   5561 C CG1 . VAL B 1 312 ? 111.450 144.815 162.241 1.00 78.11  ? 312 VAL B CG1 1 
ATOM   5562 C CG2 . VAL B 1 312 ? 110.028 142.760 162.216 1.00 78.63  ? 312 VAL B CG2 1 
ATOM   5563 N N   . PHE B 1 313 ? 113.488 144.301 159.290 1.00 80.74  ? 313 PHE B N   1 
ATOM   5564 C CA  . PHE B 1 313 ? 114.655 145.151 159.097 1.00 78.22  ? 313 PHE B CA  1 
ATOM   5565 C C   . PHE B 1 313 ? 114.238 146.343 158.250 1.00 76.59  ? 313 PHE B C   1 
ATOM   5566 O O   . PHE B 1 313 ? 113.380 146.214 157.373 1.00 75.68  ? 313 PHE B O   1 
ATOM   5567 C CB  . PHE B 1 313 ? 115.826 144.390 158.456 1.00 78.60  ? 313 PHE B CB  1 
ATOM   5568 C CG  . PHE B 1 313 ? 115.451 143.545 157.268 1.00 75.44  ? 313 PHE B CG  1 
ATOM   5569 C CD1 . PHE B 1 313 ? 115.121 144.121 156.058 1.00 79.95  ? 313 PHE B CD1 1 
ATOM   5570 C CD2 . PHE B 1 313 ? 115.466 142.167 157.359 1.00 72.74  ? 313 PHE B CD2 1 
ATOM   5571 C CE1 . PHE B 1 313 ? 114.792 143.340 154.972 1.00 80.52  ? 313 PHE B CE1 1 
ATOM   5572 C CE2 . PHE B 1 313 ? 115.135 141.383 156.277 1.00 76.17  ? 313 PHE B CE2 1 
ATOM   5573 C CZ  . PHE B 1 313 ? 114.799 141.970 155.083 1.00 77.16  ? 313 PHE B CZ  1 
ATOM   5574 N N   . GLN B 1 314 ? 114.831 147.498 158.529 1.00 90.71  ? 314 GLN B N   1 
ATOM   5575 C CA  . GLN B 1 314 ? 114.420 148.728 157.874 1.00 92.24  ? 314 GLN B CA  1 
ATOM   5576 C C   . GLN B 1 314 ? 114.930 148.771 156.438 1.00 93.29  ? 314 GLN B C   1 
ATOM   5577 O O   . GLN B 1 314 ? 115.750 147.952 156.014 1.00 94.58  ? 314 GLN B O   1 
ATOM   5578 C CB  . GLN B 1 314 ? 114.930 149.946 158.645 1.00 91.83  ? 314 GLN B CB  1 
ATOM   5579 C CG  . GLN B 1 314 ? 114.925 149.779 160.156 1.00 94.76  ? 314 GLN B CG  1 
ATOM   5580 C CD  . GLN B 1 314 ? 116.194 149.131 160.673 1.00 98.23  ? 314 GLN B CD  1 
ATOM   5581 O OE1 . GLN B 1 314 ? 117.300 149.564 160.352 1.00 97.37  ? 314 GLN B OE1 1 
ATOM   5582 N NE2 . GLN B 1 314 ? 116.039 148.082 161.471 1.00 96.56  ? 314 GLN B NE2 1 
ATOM   5583 N N   . ALA B 1 315 ? 114.425 149.749 155.682 1.00 91.53  ? 315 ALA B N   1 
ATOM   5584 C CA  . ALA B 1 315 ? 114.847 149.905 154.294 1.00 91.31  ? 315 ALA B CA  1 
ATOM   5585 C C   . ALA B 1 315 ? 116.316 150.284 154.189 1.00 90.51  ? 315 ALA B C   1 
ATOM   5586 O O   . ALA B 1 315 ? 116.979 149.927 153.210 1.00 88.47  ? 315 ALA B O   1 
ATOM   5587 C CB  . ALA B 1 315 ? 113.984 150.953 153.596 1.00 88.39  ? 315 ALA B CB  1 
ATOM   5588 N N   . SER B 1 316 ? 116.842 151.006 155.178 1.00 94.08  ? 316 SER B N   1 
ATOM   5589 C CA  . SER B 1 316 ? 118.234 151.435 155.142 1.00 94.57  ? 316 SER B CA  1 
ATOM   5590 C C   . SER B 1 316 ? 119.217 150.286 155.319 1.00 95.59  ? 316 SER B C   1 
ATOM   5591 O O   . SER B 1 316 ? 120.413 150.478 155.079 1.00 95.72  ? 316 SER B O   1 
ATOM   5592 C CB  . SER B 1 316 ? 118.478 152.489 156.221 1.00 96.66  ? 316 SER B CB  1 
ATOM   5593 O OG  . SER B 1 316 ? 117.520 153.528 156.140 1.00 99.18  ? 316 SER B OG  1 
ATOM   5594 N N   . HIS B 1 317 ? 118.756 149.114 155.740 1.00 90.63  ? 317 HIS B N   1 
ATOM   5595 C CA  . HIS B 1 317 ? 119.661 148.000 155.964 1.00 87.57  ? 317 HIS B CA  1 
ATOM   5596 C C   . HIS B 1 317 ? 120.147 147.437 154.631 1.00 82.07  ? 317 HIS B C   1 
ATOM   5597 O O   . HIS B 1 317 ? 119.381 147.376 153.667 1.00 83.19  ? 317 HIS B O   1 
ATOM   5598 C CB  . HIS B 1 317 ? 118.968 146.904 156.768 1.00 84.99  ? 317 HIS B CB  1 
ATOM   5599 C CG  . HIS B 1 317 ? 119.913 145.993 157.484 1.00 86.29  ? 317 HIS B CG  1 
ATOM   5600 N ND1 . HIS B 1 317 ? 120.014 144.650 157.195 1.00 86.78  ? 317 HIS B ND1 1 
ATOM   5601 C CD2 . HIS B 1 317 ? 120.801 146.232 158.477 1.00 85.48  ? 317 HIS B CD2 1 
ATOM   5602 C CE1 . HIS B 1 317 ? 120.924 144.101 157.978 1.00 89.56  ? 317 HIS B CE1 1 
ATOM   5603 N NE2 . HIS B 1 317 ? 121.417 145.040 158.765 1.00 91.70  ? 317 HIS B NE2 1 
ATOM   5604 N N   . PRO B 1 318 ? 121.410 147.015 154.544 1.00 79.28  ? 318 PRO B N   1 
ATOM   5605 C CA  . PRO B 1 318 ? 121.893 146.404 153.294 1.00 77.45  ? 318 PRO B CA  1 
ATOM   5606 C C   . PRO B 1 318 ? 121.175 145.120 152.937 1.00 80.48  ? 318 PRO B C   1 
ATOM   5607 O O   . PRO B 1 318 ? 121.237 144.698 151.778 1.00 84.40  ? 318 PRO B O   1 
ATOM   5608 C CB  . PRO B 1 318 ? 123.384 146.152 153.554 1.00 80.43  ? 318 PRO B CB  1 
ATOM   5609 C CG  . PRO B 1 318 ? 123.689 146.669 154.895 1.00 86.25  ? 318 PRO B CG  1 
ATOM   5610 C CD  . PRO B 1 318 ? 122.473 147.230 155.538 1.00 86.14  ? 318 PRO B CD  1 
ATOM   5611 N N   . LEU B 1 319 ? 120.513 144.472 153.892 1.00 80.18  ? 319 LEU B N   1 
ATOM   5612 C CA  . LEU B 1 319 ? 119.677 143.323 153.573 1.00 77.99  ? 319 LEU B CA  1 
ATOM   5613 C C   . LEU B 1 319 ? 118.403 143.719 152.843 1.00 77.43  ? 319 LEU B C   1 
ATOM   5614 O O   . LEU B 1 319 ? 117.741 142.847 152.274 1.00 75.78  ? 319 LEU B O   1 
ATOM   5615 C CB  . LEU B 1 319 ? 119.321 142.565 154.851 1.00 79.49  ? 319 LEU B CB  1 
ATOM   5616 C CG  . LEU B 1 319 ? 119.262 141.041 154.818 1.00 78.83  ? 319 LEU B CG  1 
ATOM   5617 C CD1 . LEU B 1 319 ? 120.486 140.480 154.143 1.00 79.81  ? 319 LEU B CD1 1 
ATOM   5618 C CD2 . LEU B 1 319 ? 119.152 140.505 156.227 1.00 76.09  ? 319 LEU B CD2 1 
ATOM   5619 N N   . SER B 1 320 ? 118.044 145.003 152.851 1.00 76.14  ? 320 SER B N   1 
ATOM   5620 C CA  . SER B 1 320 ? 116.820 145.459 152.208 1.00 71.54  ? 320 SER B CA  1 
ATOM   5621 C C   . SER B 1 320 ? 117.093 146.071 150.842 1.00 70.22  ? 320 SER B C   1 
ATOM   5622 O O   . SER B 1 320 ? 116.573 145.590 149.834 1.00 69.56  ? 320 SER B O   1 
ATOM   5623 C CB  . SER B 1 320 ? 116.099 146.475 153.091 1.00 72.74  ? 320 SER B CB  1 
ATOM   5624 O OG  . SER B 1 320 ? 115.211 147.267 152.323 1.00 82.06  ? 320 SER B OG  1 
ATOM   5625 N N   . TRP B 1 321 ? 117.905 147.129 150.791 1.00 73.08  ? 321 TRP B N   1 
ATOM   5626 C CA  . TRP B 1 321 ? 118.188 147.759 149.506 1.00 69.60  ? 321 TRP B CA  1 
ATOM   5627 C C   . TRP B 1 321 ? 119.163 146.934 148.683 1.00 66.89  ? 321 TRP B C   1 
ATOM   5628 O O   . TRP B 1 321 ? 119.204 147.067 147.456 1.00 73.67  ? 321 TRP B O   1 
ATOM   5629 C CB  . TRP B 1 321 ? 118.718 149.181 149.704 1.00 71.24  ? 321 TRP B CB  1 
ATOM   5630 C CG  . TRP B 1 321 ? 120.002 149.286 150.461 1.00 70.77  ? 321 TRP B CG  1 
ATOM   5631 C CD1 . TRP B 1 321 ? 120.147 149.633 151.766 1.00 74.20  ? 321 TRP B CD1 1 
ATOM   5632 C CD2 . TRP B 1 321 ? 121.325 149.069 149.955 1.00 71.76  ? 321 TRP B CD2 1 
ATOM   5633 N NE1 . TRP B 1 321 ? 121.474 149.636 152.112 1.00 72.95  ? 321 TRP B NE1 1 
ATOM   5634 C CE2 . TRP B 1 321 ? 122.217 149.293 151.016 1.00 68.91  ? 321 TRP B CE2 1 
ATOM   5635 C CE3 . TRP B 1 321 ? 121.840 148.703 148.710 1.00 75.90  ? 321 TRP B CE3 1 
ATOM   5636 C CZ2 . TRP B 1 321 ? 123.591 149.160 150.873 1.00 74.02  ? 321 TRP B CZ2 1 
ATOM   5637 C CZ3 . TRP B 1 321 ? 123.204 148.572 148.571 1.00 76.01  ? 321 TRP B CZ3 1 
ATOM   5638 C CH2 . TRP B 1 321 ? 124.064 148.798 149.645 1.00 76.99  ? 321 TRP B CH2 1 
ATOM   5639 N N   . GLY B 1 322 ? 119.961 146.090 149.331 1.00 65.55  ? 322 GLY B N   1 
ATOM   5640 C CA  . GLY B 1 322 ? 120.831 145.202 148.581 1.00 67.08  ? 322 GLY B CA  1 
ATOM   5641 C C   . GLY B 1 322 ? 120.047 144.208 147.748 1.00 72.95  ? 322 GLY B C   1 
ATOM   5642 O O   . GLY B 1 322 ? 120.432 143.876 146.626 1.00 79.57  ? 322 GLY B O   1 
ATOM   5643 N N   . ARG B 1 323 ? 118.936 143.714 148.293 1.00 64.99  ? 323 ARG B N   1 
ATOM   5644 C CA  . ARG B 1 323 ? 118.104 142.777 147.549 1.00 58.07  ? 323 ARG B CA  1 
ATOM   5645 C C   . ARG B 1 323 ? 117.410 143.460 146.378 1.00 61.02  ? 323 ARG B C   1 
ATOM   5646 O O   . ARG B 1 323 ? 117.275 142.871 145.301 1.00 64.51  ? 323 ARG B O   1 
ATOM   5647 C CB  . ARG B 1 323 ? 117.079 142.134 148.478 1.00 56.69  ? 323 ARG B CB  1 
ATOM   5648 C CG  . ARG B 1 323 ? 116.146 141.172 147.783 1.00 57.04  ? 323 ARG B CG  1 
ATOM   5649 C CD  . ARG B 1 323 ? 115.087 140.647 148.728 1.00 56.86  ? 323 ARG B CD  1 
ATOM   5650 N NE  . ARG B 1 323 ? 113.960 140.078 148.003 1.00 61.50  ? 323 ARG B NE  1 
ATOM   5651 C CZ  . ARG B 1 323 ? 113.082 140.785 147.306 1.00 62.70  ? 323 ARG B CZ  1 
ATOM   5652 N NH1 . ARG B 1 323 ? 113.140 142.104 147.256 1.00 61.78  ? 323 ARG B NH1 1 
ATOM   5653 N NH2 . ARG B 1 323 ? 112.118 140.152 146.645 1.00 64.29  ? 323 ARG B NH2 1 
ATOM   5654 N N   . ILE B 1 324 ? 116.958 144.701 146.568 1.00 64.40  ? 324 ILE B N   1 
ATOM   5655 C CA  . ILE B 1 324 ? 116.261 145.408 145.495 1.00 57.00  ? 324 ILE B CA  1 
ATOM   5656 C C   . ILE B 1 324 ? 117.204 145.670 144.330 1.00 61.35  ? 324 ILE B C   1 
ATOM   5657 O O   . ILE B 1 324 ? 116.819 145.559 143.161 1.00 70.65  ? 324 ILE B O   1 
ATOM   5658 C CB  . ILE B 1 324 ? 115.641 146.715 146.016 1.00 60.85  ? 324 ILE B CB  1 
ATOM   5659 C CG1 . ILE B 1 324 ? 114.914 146.482 147.335 1.00 66.13  ? 324 ILE B CG1 1 
ATOM   5660 C CG2 . ILE B 1 324 ? 114.672 147.267 144.999 1.00 63.41  ? 324 ILE B CG2 1 
ATOM   5661 C CD1 . ILE B 1 324 ? 113.816 145.466 147.245 1.00 66.95  ? 324 ILE B CD1 1 
ATOM   5662 N N   . LEU B 1 325 ? 118.450 146.043 144.629 1.00 68.29  ? 325 LEU B N   1 
ATOM   5663 C CA  . LEU B 1 325 ? 119.425 146.247 143.563 1.00 67.09  ? 325 LEU B CA  1 
ATOM   5664 C C   . LEU B 1 325 ? 119.689 144.954 142.809 1.00 67.97  ? 325 LEU B C   1 
ATOM   5665 O O   . LEU B 1 325 ? 119.821 144.959 141.581 1.00 74.30  ? 325 LEU B O   1 
ATOM   5666 C CB  . LEU B 1 325 ? 120.730 146.802 144.129 1.00 67.14  ? 325 LEU B CB  1 
ATOM   5667 C CG  . LEU B 1 325 ? 120.730 148.243 144.636 1.00 73.70  ? 325 LEU B CG  1 
ATOM   5668 C CD1 . LEU B 1 325 ? 122.148 148.771 144.693 1.00 71.51  ? 325 LEU B CD1 1 
ATOM   5669 C CD2 . LEU B 1 325 ? 119.859 149.130 143.768 1.00 73.86  ? 325 LEU B CD2 1 
ATOM   5670 N N   . PHE B 1 326 ? 119.782 143.836 143.529 1.00 58.85  ? 326 PHE B N   1 
ATOM   5671 C CA  . PHE B 1 326 ? 120.026 142.554 142.878 1.00 60.55  ? 326 PHE B CA  1 
ATOM   5672 C C   . PHE B 1 326 ? 118.860 142.160 141.982 1.00 64.69  ? 326 PHE B C   1 
ATOM   5673 O O   . PHE B 1 326 ? 119.057 141.721 140.844 1.00 60.63  ? 326 PHE B O   1 
ATOM   5674 C CB  . PHE B 1 326 ? 120.282 141.477 143.927 1.00 59.96  ? 326 PHE B CB  1 
ATOM   5675 C CG  . PHE B 1 326 ? 120.321 140.095 143.364 1.00 59.60  ? 326 PHE B CG  1 
ATOM   5676 C CD1 . PHE B 1 326 ? 121.221 139.768 142.372 1.00 56.34  ? 326 PHE B CD1 1 
ATOM   5677 C CD2 . PHE B 1 326 ? 119.449 139.127 143.814 1.00 61.75  ? 326 PHE B CD2 1 
ATOM   5678 C CE1 . PHE B 1 326 ? 121.256 138.502 141.850 1.00 56.58  ? 326 PHE B CE1 1 
ATOM   5679 C CE2 . PHE B 1 326 ? 119.480 137.859 143.293 1.00 66.67  ? 326 PHE B CE2 1 
ATOM   5680 C CZ  . PHE B 1 326 ? 120.384 137.546 142.309 1.00 62.12  ? 326 PHE B CZ  1 
ATOM   5681 N N   . ILE B 1 327 ? 117.632 142.306 142.480 1.00 59.01  ? 327 ILE B N   1 
ATOM   5682 C CA  . ILE B 1 327 ? 116.464 141.974 141.671 1.00 50.20  ? 327 ILE B CA  1 
ATOM   5683 C C   . ILE B 1 327 ? 116.328 142.943 140.508 1.00 60.65  ? 327 ILE B C   1 
ATOM   5684 O O   . ILE B 1 327 ? 115.825 142.577 139.440 1.00 73.83  ? 327 ILE B O   1 
ATOM   5685 C CB  . ILE B 1 327 ? 115.201 141.945 142.550 1.00 51.37  ? 327 ILE B CB  1 
ATOM   5686 C CG1 . ILE B 1 327 ? 115.323 140.844 143.598 1.00 60.29  ? 327 ILE B CG1 1 
ATOM   5687 C CG2 . ILE B 1 327 ? 113.965 141.711 141.714 1.00 52.01  ? 327 ILE B CG2 1 
ATOM   5688 C CD1 . ILE B 1 327 ? 115.564 139.479 143.012 1.00 55.89  ? 327 ILE B CD1 1 
ATOM   5689 N N   . GLY B 1 328 ? 116.770 144.187 140.686 1.00 60.33  ? 328 GLY B N   1 
ATOM   5690 C CA  . GLY B 1 328 ? 116.772 145.117 139.570 1.00 57.97  ? 328 GLY B CA  1 
ATOM   5691 C C   . GLY B 1 328 ? 117.703 144.681 138.457 1.00 60.69  ? 328 GLY B C   1 
ATOM   5692 O O   . GLY B 1 328 ? 117.350 144.743 137.279 1.00 60.72  ? 328 GLY B O   1 
ATOM   5693 N N   . GLY B 1 329 ? 118.906 144.234 138.815 1.00 54.33  ? 329 GLY B N   1 
ATOM   5694 C CA  . GLY B 1 329 ? 119.827 143.738 137.807 1.00 57.63  ? 329 GLY B CA  1 
ATOM   5695 C C   . GLY B 1 329 ? 119.369 142.431 137.193 1.00 51.79  ? 329 GLY B C   1 
ATOM   5696 O O   . GLY B 1 329 ? 119.674 142.136 136.037 1.00 51.89  ? 329 GLY B O   1 
ATOM   5697 N N   . ILE B 1 330 ? 118.647 141.621 137.966 1.00 51.25  ? 330 ILE B N   1 
ATOM   5698 C CA  . ILE B 1 330 ? 118.140 140.353 137.453 1.00 52.37  ? 330 ILE B CA  1 
ATOM   5699 C C   . ILE B 1 330 ? 117.005 140.601 136.469 1.00 49.61  ? 330 ILE B C   1 
ATOM   5700 O O   . ILE B 1 330 ? 116.822 139.853 135.503 1.00 53.47  ? 330 ILE B O   1 
ATOM   5701 C CB  . ILE B 1 330 ? 117.692 139.461 138.623 1.00 58.42  ? 330 ILE B CB  1 
ATOM   5702 C CG1 . ILE B 1 330 ? 118.903 138.843 139.295 1.00 60.94  ? 330 ILE B CG1 1 
ATOM   5703 C CG2 . ILE B 1 330 ? 116.834 138.332 138.138 1.00 49.66  ? 330 ILE B CG2 1 
ATOM   5704 C CD1 . ILE B 1 330 ? 119.912 138.369 138.333 1.00 54.58  ? 330 ILE B CD1 1 
ATOM   5705 N N   . THR B 1 331 ? 116.232 141.661 136.699 1.00 47.76  ? 331 THR B N   1 
ATOM   5706 C CA  . THR B 1 331 ? 115.031 141.914 135.912 1.00 47.37  ? 331 THR B CA  1 
ATOM   5707 C C   . THR B 1 331 ? 115.367 142.237 134.461 1.00 55.60  ? 331 THR B C   1 
ATOM   5708 O O   . THR B 1 331 ? 114.643 141.838 133.544 1.00 59.80  ? 331 THR B O   1 
ATOM   5709 C CB  . THR B 1 331 ? 114.236 143.050 136.552 1.00 55.13  ? 331 THR B CB  1 
ATOM   5710 O OG1 . THR B 1 331 ? 113.733 142.621 137.823 1.00 58.65  ? 331 THR B OG1 1 
ATOM   5711 C CG2 . THR B 1 331 ? 113.079 143.463 135.672 1.00 56.02  ? 331 THR B CG2 1 
ATOM   5712 N N   . ALA B 1 332 ? 116.463 142.959 134.232 1.00 56.25  ? 332 ALA B N   1 
ATOM   5713 C CA  . ALA B 1 332 ? 116.785 143.447 132.894 1.00 45.51  ? 332 ALA B CA  1 
ATOM   5714 C C   . ALA B 1 332 ? 116.953 142.318 131.876 1.00 49.54  ? 332 ALA B C   1 
ATOM   5715 O O   . ALA B 1 332 ? 116.358 142.396 130.796 1.00 62.25  ? 332 ALA B O   1 
ATOM   5716 C CB  . ALA B 1 332 ? 118.032 144.331 132.930 1.00 53.70  ? 332 ALA B CB  1 
ATOM   5717 N N   . PRO B 1 333 ? 117.728 141.261 132.149 1.00 50.16  ? 333 PRO B N   1 
ATOM   5718 C CA  . PRO B 1 333 ? 117.768 140.155 131.183 1.00 52.10  ? 333 PRO B CA  1 
ATOM   5719 C C   . PRO B 1 333 ? 116.533 139.279 131.218 1.00 49.37  ? 333 PRO B C   1 
ATOM   5720 O O   . PRO B 1 333 ? 116.208 138.657 130.202 1.00 56.33  ? 333 PRO B O   1 
ATOM   5721 C CB  . PRO B 1 333 ? 119.023 139.374 131.589 1.00 50.44  ? 333 PRO B CB  1 
ATOM   5722 C CG  . PRO B 1 333 ? 119.183 139.659 133.006 1.00 47.60  ? 333 PRO B CG  1 
ATOM   5723 C CD  . PRO B 1 333 ? 118.738 141.071 133.204 1.00 53.55  ? 333 PRO B CD  1 
ATOM   5724 N N   . THR B 1 334 ? 115.835 139.201 132.351 1.00 39.49  ? 334 THR B N   1 
ATOM   5725 C CA  . THR B 1 334 ? 114.649 138.356 132.428 1.00 40.06  ? 334 THR B CA  1 
ATOM   5726 C C   . THR B 1 334 ? 113.510 138.911 131.584 1.00 50.76  ? 334 THR B C   1 
ATOM   5727 O O   . THR B 1 334 ? 112.806 138.153 130.910 1.00 67.24  ? 334 THR B O   1 
ATOM   5728 C CB  . THR B 1 334 ? 114.204 138.205 133.876 1.00 48.53  ? 334 THR B CB  1 
ATOM   5729 O OG1 . THR B 1 334 ? 115.156 137.406 134.580 1.00 64.29  ? 334 THR B OG1 1 
ATOM   5730 C CG2 . THR B 1 334 ? 112.857 137.533 133.937 1.00 44.72  ? 334 THR B CG2 1 
ATOM   5731 N N   . VAL B 1 335 ? 113.312 140.229 131.607 1.00 44.61  ? 335 VAL B N   1 
ATOM   5732 C CA  . VAL B 1 335 ? 112.241 140.826 130.818 1.00 40.83  ? 335 VAL B CA  1 
ATOM   5733 C C   . VAL B 1 335 ? 112.482 140.594 129.335 1.00 47.67  ? 335 VAL B C   1 
ATOM   5734 O O   . VAL B 1 335 ? 111.551 140.304 128.577 1.00 59.13  ? 335 VAL B O   1 
ATOM   5735 C CB  . VAL B 1 335 ? 112.112 142.323 131.137 1.00 45.54  ? 335 VAL B CB  1 
ATOM   5736 C CG1 . VAL B 1 335 ? 111.202 142.982 130.137 1.00 56.51  ? 335 VAL B CG1 1 
ATOM   5737 C CG2 . VAL B 1 335 ? 111.586 142.518 132.534 1.00 45.86  ? 335 VAL B CG2 1 
ATOM   5738 N N   . ARG B 1 336 ? 113.731 140.720 128.895 1.00 53.86  ? 336 ARG B N   1 
ATOM   5739 C CA  . ARG B 1 336 ? 114.031 140.548 127.481 1.00 59.39  ? 336 ARG B CA  1 
ATOM   5740 C C   . ARG B 1 336 ? 113.988 139.088 127.054 1.00 59.18  ? 336 ARG B C   1 
ATOM   5741 O O   . ARG B 1 336 ? 113.747 138.803 125.878 1.00 65.56  ? 336 ARG B O   1 
ATOM   5742 C CB  . ARG B 1 336 ? 115.395 141.150 127.160 1.00 58.26  ? 336 ARG B CB  1 
ATOM   5743 C CG  . ARG B 1 336 ? 115.502 141.655 125.743 1.00 67.44  ? 336 ARG B CG  1 
ATOM   5744 C CD  . ARG B 1 336 ? 114.550 142.810 125.502 1.00 70.54  ? 336 ARG B CD  1 
ATOM   5745 N NE  . ARG B 1 336 ? 115.239 144.094 125.525 1.00 73.57  ? 336 ARG B NE  1 
ATOM   5746 C CZ  . ARG B 1 336 ? 114.632 145.265 125.655 1.00 71.61  ? 336 ARG B CZ  1 
ATOM   5747 N NH1 . ARG B 1 336 ? 113.321 145.350 125.795 1.00 69.26  ? 336 ARG B NH1 1 
ATOM   5748 N NH2 . ARG B 1 336 ? 115.360 146.377 125.643 1.00 69.08  ? 336 ARG B NH2 1 
ATOM   5749 N N   . GLN B 1 337 ? 114.237 138.156 127.973 1.00 45.72  ? 337 GLN B N   1 
ATOM   5750 C CA  . GLN B 1 337 ? 114.086 136.742 127.656 1.00 36.54  ? 337 GLN B CA  1 
ATOM   5751 C C   . GLN B 1 337 ? 112.624 136.321 127.653 1.00 47.70  ? 337 GLN B C   1 
ATOM   5752 O O   . GLN B 1 337 ? 112.220 135.481 126.845 1.00 63.16  ? 337 GLN B O   1 
ATOM   5753 C CB  . GLN B 1 337 ? 114.877 135.894 128.644 1.00 38.48  ? 337 GLN B CB  1 
ATOM   5754 C CG  . GLN B 1 337 ? 116.363 136.045 128.507 1.00 44.27  ? 337 GLN B CG  1 
ATOM   5755 C CD  . GLN B 1 337 ? 117.105 134.891 129.111 1.00 47.49  ? 337 GLN B CD  1 
ATOM   5756 O OE1 . GLN B 1 337 ? 116.525 134.074 129.812 1.00 50.81  ? 337 GLN B OE1 1 
ATOM   5757 N NE2 . GLN B 1 337 ? 118.394 134.809 128.837 1.00 53.49  ? 337 GLN B NE2 1 
ATOM   5758 N N   . TYR B 1 338 ? 111.824 136.872 128.566 1.00 51.54  ? 338 TYR B N   1 
ATOM   5759 C CA  . TYR B 1 338 ? 110.397 136.577 128.562 1.00 46.05  ? 338 TYR B CA  1 
ATOM   5760 C C   . TYR B 1 338 ? 109.721 137.162 127.333 1.00 55.98  ? 338 TYR B C   1 
ATOM   5761 O O   . TYR B 1 338 ? 108.825 136.538 126.755 1.00 65.94  ? 338 TYR B O   1 
ATOM   5762 C CB  . TYR B 1 338 ? 109.739 137.113 129.827 1.00 47.01  ? 338 TYR B CB  1 
ATOM   5763 C CG  . TYR B 1 338 ? 108.312 136.664 129.986 1.00 51.90  ? 338 TYR B CG  1 
ATOM   5764 C CD1 . TYR B 1 338 ? 108.013 135.416 130.499 1.00 58.43  ? 338 TYR B CD1 1 
ATOM   5765 C CD2 . TYR B 1 338 ? 107.265 137.483 129.615 1.00 58.93  ? 338 TYR B CD2 1 
ATOM   5766 C CE1 . TYR B 1 338 ? 106.713 135.004 130.644 1.00 57.12  ? 338 TYR B CE1 1 
ATOM   5767 C CE2 . TYR B 1 338 ? 105.961 137.075 129.756 1.00 57.25  ? 338 TYR B CE2 1 
ATOM   5768 C CZ  . TYR B 1 338 ? 105.692 135.835 130.269 1.00 54.58  ? 338 TYR B CZ  1 
ATOM   5769 O OH  . TYR B 1 338 ? 104.391 135.425 130.411 1.00 59.87  ? 338 TYR B OH  1 
ATOM   5770 N N   . TYR B 1 339 ? 110.121 138.367 126.928 1.00 56.64  ? 339 TYR B N   1 
ATOM   5771 C CA  . TYR B 1 339 ? 109.567 138.952 125.714 1.00 55.64  ? 339 TYR B CA  1 
ATOM   5772 C C   . TYR B 1 339 ? 109.934 138.128 124.492 1.00 62.72  ? 339 TYR B C   1 
ATOM   5773 O O   . TYR B 1 339 ? 109.108 137.933 123.595 1.00 72.37  ? 339 TYR B O   1 
ATOM   5774 C CB  . TYR B 1 339 ? 110.052 140.384 125.541 1.00 56.78  ? 339 TYR B CB  1 
ATOM   5775 C CG  . TYR B 1 339 ? 109.578 140.998 124.252 1.00 62.27  ? 339 TYR B CG  1 
ATOM   5776 C CD1 . TYR B 1 339 ? 108.267 141.412 124.106 1.00 64.14  ? 339 TYR B CD1 1 
ATOM   5777 C CD2 . TYR B 1 339 ? 110.433 141.144 123.176 1.00 60.63  ? 339 TYR B CD2 1 
ATOM   5778 C CE1 . TYR B 1 339 ? 107.827 141.969 122.935 1.00 57.87  ? 339 TYR B CE1 1 
ATOM   5779 C CE2 . TYR B 1 339 ? 109.999 141.695 121.997 1.00 56.62  ? 339 TYR B CE2 1 
ATOM   5780 C CZ  . TYR B 1 339 ? 108.693 142.105 121.882 1.00 58.88  ? 339 TYR B CZ  1 
ATOM   5781 O OH  . TYR B 1 339 ? 108.252 142.658 120.705 1.00 69.50  ? 339 TYR B OH  1 
ATOM   5782 N N   . ALA B 1 340 ? 111.177 137.650 124.429 1.00 56.79  ? 340 ALA B N   1 
ATOM   5783 C CA  . ALA B 1 340 ? 111.588 136.826 123.300 1.00 53.43  ? 340 ALA B CA  1 
ATOM   5784 C C   . ALA B 1 340 ? 110.786 135.535 123.242 1.00 58.03  ? 340 ALA B C   1 
ATOM   5785 O O   . ALA B 1 340 ? 110.349 135.117 122.166 1.00 73.84  ? 340 ALA B O   1 
ATOM   5786 C CB  . ALA B 1 340 ? 113.082 136.528 123.384 1.00 55.41  ? 340 ALA B CB  1 
ATOM   5787 N N   . TYR B 1 341 ? 110.578 134.891 124.390 1.00 55.92  ? 341 TYR B N   1 
ATOM   5788 C CA  . TYR B 1 341 ? 109.807 133.653 124.407 1.00 60.18  ? 341 TYR B CA  1 
ATOM   5789 C C   . TYR B 1 341 ? 108.348 133.903 124.053 1.00 61.84  ? 341 TYR B C   1 
ATOM   5790 O O   . TYR B 1 341 ? 107.732 133.102 123.345 1.00 67.78  ? 341 TYR B O   1 
ATOM   5791 C CB  . TYR B 1 341 ? 109.916 132.983 125.774 1.00 55.81  ? 341 TYR B CB  1 
ATOM   5792 C CG  . TYR B 1 341 ? 109.165 131.680 125.875 1.00 56.68  ? 341 TYR B CG  1 
ATOM   5793 C CD1 . TYR B 1 341 ? 109.738 130.494 125.453 1.00 60.68  ? 341 TYR B CD1 1 
ATOM   5794 C CD2 . TYR B 1 341 ? 107.885 131.634 126.397 1.00 65.42  ? 341 TYR B CD2 1 
ATOM   5795 C CE1 . TYR B 1 341 ? 109.058 129.302 125.545 1.00 63.89  ? 341 TYR B CE1 1 
ATOM   5796 C CE2 . TYR B 1 341 ? 107.198 130.446 126.490 1.00 70.39  ? 341 TYR B CE2 1 
ATOM   5797 C CZ  . TYR B 1 341 ? 107.789 129.283 126.063 1.00 70.42  ? 341 TYR B CZ  1 
ATOM   5798 O OH  . TYR B 1 341 ? 107.106 128.094 126.155 1.00 72.88  ? 341 TYR B OH  1 
ATOM   5799 N N   . LEU B 1 342 ? 107.775 135.000 124.545 1.00 57.43  ? 342 LEU B N   1 
ATOM   5800 C CA  . LEU B 1 342 ? 106.358 135.258 124.316 1.00 62.94  ? 342 LEU B CA  1 
ATOM   5801 C C   . LEU B 1 342 ? 106.049 135.484 122.844 1.00 65.63  ? 342 LEU B C   1 
ATOM   5802 O O   . LEU B 1 342 ? 105.054 134.963 122.328 1.00 67.55  ? 342 LEU B O   1 
ATOM   5803 C CB  . LEU B 1 342 ? 105.904 136.465 125.131 1.00 64.64  ? 342 LEU B CB  1 
ATOM   5804 C CG  . LEU B 1 342 ? 104.418 136.503 125.478 1.00 63.98  ? 342 LEU B CG  1 
ATOM   5805 C CD1 . LEU B 1 342 ? 103.850 135.102 125.600 1.00 63.09  ? 342 LEU B CD1 1 
ATOM   5806 C CD2 . LEU B 1 342 ? 104.193 137.294 126.746 1.00 64.32  ? 342 LEU B CD2 1 
ATOM   5807 N N   . THR B 1 343 ? 106.880 136.259 122.151 1.00 62.16  ? 343 THR B N   1 
ATOM   5808 C CA  . THR B 1 343 ? 106.524 136.726 120.817 1.00 65.17  ? 343 THR B CA  1 
ATOM   5809 C C   . THR B 1 343 ? 106.997 135.776 119.723 1.00 68.36  ? 343 THR B C   1 
ATOM   5810 O O   . THR B 1 343 ? 106.184 135.252 118.955 1.00 76.33  ? 343 THR B O   1 
ATOM   5811 C CB  . THR B 1 343 ? 107.098 138.124 120.581 1.00 67.15  ? 343 THR B CB  1 
ATOM   5812 O OG1 . THR B 1 343 ? 108.526 138.069 120.651 1.00 64.99  ? 343 THR B OG1 1 
ATOM   5813 C CG2 . THR B 1 343 ? 106.581 139.077 121.629 1.00 66.59  ? 343 THR B CG2 1 
ATOM   5814 N N   . ASP B 1 344 ? 108.304 135.547 119.639 1.00 74.10  ? 344 ASP B N   1 
ATOM   5815 C CA  . ASP B 1 344 ? 108.836 134.789 118.517 1.00 79.09  ? 344 ASP B CA  1 
ATOM   5816 C C   . ASP B 1 344 ? 108.391 133.337 118.581 1.00 82.12  ? 344 ASP B C   1 
ATOM   5817 O O   . ASP B 1 344 ? 108.703 132.625 119.539 1.00 73.07  ? 344 ASP B O   1 
ATOM   5818 C CB  . ASP B 1 344 ? 110.357 134.869 118.468 1.00 72.62  ? 344 ASP B CB  1 
ATOM   5819 C CG  . ASP B 1 344 ? 110.877 134.928 117.052 1.00 81.72  ? 344 ASP B CG  1 
ATOM   5820 O OD1 . ASP B 1 344 ? 110.264 135.638 116.227 1.00 85.58  ? 344 ASP B OD1 1 
ATOM   5821 O OD2 . ASP B 1 344 ? 111.867 134.242 116.746 1.00 85.60  ? 344 ASP B OD2 1 
ATOM   5822 N N   . THR B 1 345 ? 107.660 132.893 117.558 1.00 90.20  ? 345 THR B N   1 
ATOM   5823 C CA  . THR B 1 345 ? 107.169 131.523 117.520 1.00 88.57  ? 345 THR B CA  1 
ATOM   5824 C C   . THR B 1 345 ? 108.281 130.514 117.276 1.00 91.25  ? 345 THR B C   1 
ATOM   5825 O O   . THR B 1 345 ? 108.058 129.312 117.445 1.00 89.79  ? 345 THR B O   1 
ATOM   5826 C CB  . THR B 1 345 ? 106.099 131.384 116.440 1.00 88.17  ? 345 THR B CB  1 
ATOM   5827 O OG1 . THR B 1 345 ? 105.666 130.020 116.366 1.00 90.88  ? 345 THR B OG1 1 
ATOM   5828 C CG2 . THR B 1 345 ? 106.654 131.818 115.092 1.00 83.81  ? 345 THR B CG2 1 
ATOM   5829 N N   . GLN B 1 346 ? 109.466 130.970 116.871 1.00 91.47  ? 346 GLN B N   1 
ATOM   5830 C CA  . GLN B 1 346 ? 110.588 130.058 116.697 1.00 85.43  ? 346 GLN B CA  1 
ATOM   5831 C C   . GLN B 1 346 ? 111.220 129.668 118.025 1.00 83.52  ? 346 GLN B C   1 
ATOM   5832 O O   . GLN B 1 346 ? 111.711 128.544 118.164 1.00 88.97  ? 346 GLN B O   1 
ATOM   5833 C CB  . GLN B 1 346 ? 111.638 130.686 115.781 1.00 86.50  ? 346 GLN B CB  1 
ATOM   5834 C CG  . GLN B 1 346 ? 111.105 131.078 114.416 1.00 92.84  ? 346 GLN B CG  1 
ATOM   5835 C CD  . GLN B 1 346 ? 111.650 130.199 113.312 1.00 95.51  ? 346 GLN B CD  1 
ATOM   5836 O OE1 . GLN B 1 346 ? 111.209 129.065 113.134 1.00 94.46  ? 346 GLN B OE1 1 
ATOM   5837 N NE2 . GLN B 1 346 ? 112.618 130.718 112.564 1.00 92.61  ? 346 GLN B NE2 1 
ATOM   5838 N N   . CYS B 1 347 ? 111.223 130.572 119.001 1.00 78.22  ? 347 CYS B N   1 
ATOM   5839 C CA  . CYS B 1 347 ? 111.786 130.268 120.310 1.00 75.78  ? 347 CYS B CA  1 
ATOM   5840 C C   . CYS B 1 347 ? 110.863 129.310 121.050 1.00 79.99  ? 347 CYS B C   1 
ATOM   5841 O O   . CYS B 1 347 ? 109.705 129.640 121.326 1.00 83.67  ? 347 CYS B O   1 
ATOM   5842 C CB  . CYS B 1 347 ? 111.990 131.551 121.110 1.00 75.06  ? 347 CYS B CB  1 
ATOM   5843 S SG  . CYS B 1 347 ? 113.000 132.794 120.270 1.00 83.35  ? 347 CYS B SG  1 
ATOM   5844 N N   . LYS B 1 348 ? 111.377 128.122 121.366 1.00 76.71  ? 348 LYS B N   1 
ATOM   5845 C CA  . LYS B 1 348 ? 110.596 127.067 121.997 1.00 73.31  ? 348 LYS B CA  1 
ATOM   5846 C C   . LYS B 1 348 ? 111.211 126.619 123.316 1.00 79.52  ? 348 LYS B C   1 
ATOM   5847 O O   . LYS B 1 348 ? 110.933 125.520 123.794 1.00 85.61  ? 348 LYS B O   1 
ATOM   5848 C CB  . LYS B 1 348 ? 110.434 125.879 121.052 1.00 68.10  ? 348 LYS B CB  1 
ATOM   5849 C CG  . LYS B 1 348 ? 109.394 126.104 119.974 1.00 73.78  ? 348 LYS B CG  1 
ATOM   5850 C CD  . LYS B 1 348 ? 109.838 125.545 118.639 1.00 82.03  ? 348 LYS B CD  1 
ATOM   5851 C CE  . LYS B 1 348 ? 108.681 125.523 117.657 1.00 83.77  ? 348 LYS B CE  1 
ATOM   5852 N NZ  . LYS B 1 348 ? 107.613 126.484 118.050 1.00 79.96  ? 348 LYS B NZ  1 
ATOM   5853 N N   . ARG B 1 349 ? 112.052 127.458 123.912 1.00 67.19  ? 349 ARG B N   1 
ATOM   5854 C CA  . ARG B 1 349 ? 112.576 127.186 125.242 1.00 59.80  ? 349 ARG B CA  1 
ATOM   5855 C C   . ARG B 1 349 ? 112.810 128.509 125.948 1.00 61.73  ? 349 ARG B C   1 
ATOM   5856 O O   . ARG B 1 349 ? 113.374 129.433 125.358 1.00 68.93  ? 349 ARG B O   1 
ATOM   5857 C CB  . ARG B 1 349 ? 113.871 126.376 125.186 1.00 62.09  ? 349 ARG B CB  1 
ATOM   5858 C CG  . ARG B 1 349 ? 114.109 125.557 126.433 1.00 62.86  ? 349 ARG B CG  1 
ATOM   5859 C CD  . ARG B 1 349 ? 115.532 125.058 126.527 1.00 59.64  ? 349 ARG B CD  1 
ATOM   5860 N NE  . ARG B 1 349 ? 116.049 125.195 127.881 1.00 62.67  ? 349 ARG B NE  1 
ATOM   5861 C CZ  . ARG B 1 349 ? 117.290 124.907 128.239 1.00 63.02  ? 349 ARG B CZ  1 
ATOM   5862 N NH1 . ARG B 1 349 ? 118.168 124.447 127.367 1.00 65.36  ? 349 ARG B NH1 1 
ATOM   5863 N NH2 . ARG B 1 349 ? 117.660 125.085 129.502 1.00 64.12  ? 349 ARG B NH2 1 
ATOM   5864 N N   . VAL B 1 350 ? 112.373 128.599 127.197 1.00 56.54  ? 350 VAL B N   1 
ATOM   5865 C CA  . VAL B 1 350 ? 112.550 129.818 127.975 1.00 56.06  ? 350 VAL B CA  1 
ATOM   5866 C C   . VAL B 1 350 ? 113.979 129.871 128.490 1.00 57.14  ? 350 VAL B C   1 
ATOM   5867 O O   . VAL B 1 350 ? 114.556 128.850 128.881 1.00 64.62  ? 350 VAL B O   1 
ATOM   5868 C CB  . VAL B 1 350 ? 111.521 129.889 129.118 1.00 52.28  ? 350 VAL B CB  1 
ATOM   5869 C CG1 . VAL B 1 350 ? 111.760 128.797 130.137 1.00 50.83  ? 350 VAL B CG1 1 
ATOM   5870 C CG2 . VAL B 1 350 ? 111.546 131.257 129.766 1.00 52.44  ? 350 VAL B CG2 1 
ATOM   5871 N N   . GLY B 1 351 ? 114.570 131.061 128.458 1.00 52.45  ? 351 GLY B N   1 
ATOM   5872 C CA  . GLY B 1 351 ? 115.963 131.197 128.827 1.00 56.69  ? 351 GLY B CA  1 
ATOM   5873 C C   . GLY B 1 351 ? 116.211 130.819 130.273 1.00 49.68  ? 351 GLY B C   1 
ATOM   5874 O O   . GLY B 1 351 ? 115.325 130.867 131.123 1.00 50.64  ? 351 GLY B O   1 
ATOM   5875 N N   . THR B 1 352 ? 117.454 130.422 130.547 1.00 48.69  ? 352 THR B N   1 
ATOM   5876 C CA  . THR B 1 352 ? 117.784 129.934 131.879 1.00 50.62  ? 352 THR B CA  1 
ATOM   5877 C C   . THR B 1 352 ? 117.718 131.042 132.920 1.00 54.81  ? 352 THR B C   1 
ATOM   5878 O O   . THR B 1 352 ? 117.390 130.777 134.081 1.00 63.93  ? 352 THR B O   1 
ATOM   5879 C CB  . THR B 1 352 ? 119.165 129.286 131.875 1.00 55.34  ? 352 THR B CB  1 
ATOM   5880 O OG1 . THR B 1 352 ? 119.276 128.413 130.746 1.00 57.74  ? 352 THR B OG1 1 
ATOM   5881 C CG2 . THR B 1 352 ? 119.367 128.474 133.135 1.00 56.34  ? 352 THR B CG2 1 
ATOM   5882 N N   . GLN B 1 353 ? 118.019 132.282 132.538 1.00 48.11  ? 353 GLN B N   1 
ATOM   5883 C CA  . GLN B 1 353 ? 117.896 133.382 133.488 1.00 45.18  ? 353 GLN B CA  1 
ATOM   5884 C C   . GLN B 1 353 ? 116.438 133.697 133.791 1.00 48.23  ? 353 GLN B C   1 
ATOM   5885 O O   . GLN B 1 353 ? 116.089 133.990 134.938 1.00 47.25  ? 353 GLN B O   1 
ATOM   5886 C CB  . GLN B 1 353 ? 118.610 134.620 132.960 1.00 51.02  ? 353 GLN B CB  1 
ATOM   5887 C CG  . GLN B 1 353 ? 118.261 135.894 133.699 1.00 49.20  ? 353 GLN B CG  1 
ATOM   5888 C CD  . GLN B 1 353 ? 118.950 136.022 135.040 1.00 46.34  ? 353 GLN B CD  1 
ATOM   5889 O OE1 . GLN B 1 353 ? 119.194 135.040 135.733 1.00 33.64  ? 353 GLN B OE1 1 
ATOM   5890 N NE2 . GLN B 1 353 ? 119.273 137.247 135.409 1.00 56.98  ? 353 GLN B NE2 1 
ATOM   5891 N N   . CYS B 1 354 ? 115.573 133.651 132.776 1.00 48.62  ? 354 CYS B N   1 
ATOM   5892 C CA  . CYS B 1 354 ? 114.149 133.857 133.015 1.00 39.98  ? 354 CYS B CA  1 
ATOM   5893 C C   . CYS B 1 354 ? 113.554 132.720 133.828 1.00 39.99  ? 354 CYS B C   1 
ATOM   5894 O O   . CYS B 1 354 ? 112.595 132.930 134.575 1.00 48.86  ? 354 CYS B O   1 
ATOM   5895 C CB  . CYS B 1 354 ? 113.402 133.999 131.694 1.00 48.94  ? 354 CYS B CB  1 
ATOM   5896 S SG  . CYS B 1 354 ? 111.636 134.268 131.876 1.00 61.41  ? 354 CYS B SG  1 
ATOM   5897 N N   . TRP B 1 355 ? 114.095 131.513 133.683 1.00 43.57  ? 355 TRP B N   1 
ATOM   5898 C CA  . TRP B 1 355 ? 113.659 130.400 134.516 1.00 39.81  ? 355 TRP B CA  1 
ATOM   5899 C C   . TRP B 1 355 ? 113.992 130.654 135.978 1.00 42.73  ? 355 TRP B C   1 
ATOM   5900 O O   . TRP B 1 355 ? 113.137 130.501 136.856 1.00 46.66  ? 355 TRP B O   1 
ATOM   5901 C CB  . TRP B 1 355 ? 114.314 129.108 134.033 1.00 38.63  ? 355 TRP B CB  1 
ATOM   5902 C CG  . TRP B 1 355 ? 113.815 127.880 134.707 1.00 42.11  ? 355 TRP B CG  1 
ATOM   5903 C CD1 . TRP B 1 355 ? 112.797 127.086 134.294 1.00 45.93  ? 355 TRP B CD1 1 
ATOM   5904 C CD2 . TRP B 1 355 ? 114.315 127.295 135.915 1.00 49.35  ? 355 TRP B CD2 1 
ATOM   5905 N NE1 . TRP B 1 355 ? 112.629 126.040 135.162 1.00 47.00  ? 355 TRP B NE1 1 
ATOM   5906 C CE2 . TRP B 1 355 ? 113.549 126.149 136.170 1.00 45.44  ? 355 TRP B CE2 1 
ATOM   5907 C CE3 . TRP B 1 355 ? 115.335 127.632 136.806 1.00 49.66  ? 355 TRP B CE3 1 
ATOM   5908 C CZ2 . TRP B 1 355 ? 113.767 125.339 137.276 1.00 44.44  ? 355 TRP B CZ2 1 
ATOM   5909 C CZ3 . TRP B 1 355 ? 115.549 126.825 137.903 1.00 44.74  ? 355 TRP B CZ3 1 
ATOM   5910 C CH2 . TRP B 1 355 ? 114.770 125.694 138.128 1.00 43.52  ? 355 TRP B CH2 1 
ATOM   5911 N N   . VAL B 1 356 ? 115.233 131.056 136.255 1.00 40.38  ? 356 VAL B N   1 
ATOM   5912 C CA  . VAL B 1 356 ? 115.674 131.228 137.635 1.00 36.35  ? 356 VAL B CA  1 
ATOM   5913 C C   . VAL B 1 356 ? 114.918 132.365 138.305 1.00 45.23  ? 356 VAL B C   1 
ATOM   5914 O O   . VAL B 1 356 ? 114.488 132.244 139.457 1.00 55.38  ? 356 VAL B O   1 
ATOM   5915 C CB  . VAL B 1 356 ? 117.194 131.449 137.685 1.00 33.38  ? 356 VAL B CB  1 
ATOM   5916 C CG1 . VAL B 1 356 ? 117.596 131.953 139.042 1.00 33.80  ? 356 VAL B CG1 1 
ATOM   5917 C CG2 . VAL B 1 356 ? 117.916 130.162 137.366 1.00 33.20  ? 356 VAL B CG2 1 
ATOM   5918 N N   . PHE B 1 357 ? 114.739 133.487 137.603 1.00 39.69  ? 357 PHE B N   1 
ATOM   5919 C CA  . PHE B 1 357 ? 113.959 134.581 138.170 1.00 39.41  ? 357 PHE B CA  1 
ATOM   5920 C C   . PHE B 1 357 ? 112.515 134.188 138.432 1.00 40.54  ? 357 PHE B C   1 
ATOM   5921 O O   . PHE B 1 357 ? 111.892 134.743 139.340 1.00 50.02  ? 357 PHE B O   1 
ATOM   5922 C CB  . PHE B 1 357 ? 113.979 135.798 137.255 1.00 38.97  ? 357 PHE B CB  1 
ATOM   5923 C CG  . PHE B 1 357 ? 113.166 136.948 137.770 1.00 37.77  ? 357 PHE B CG  1 
ATOM   5924 C CD1 . PHE B 1 357 ? 113.612 137.705 138.830 1.00 44.34  ? 357 PHE B CD1 1 
ATOM   5925 C CD2 . PHE B 1 357 ? 111.947 137.257 137.211 1.00 45.83  ? 357 PHE B CD2 1 
ATOM   5926 C CE1 . PHE B 1 357 ? 112.872 138.758 139.302 1.00 48.64  ? 357 PHE B CE1 1 
ATOM   5927 C CE2 . PHE B 1 357 ? 111.204 138.307 137.685 1.00 47.20  ? 357 PHE B CE2 1 
ATOM   5928 C CZ  . PHE B 1 357 ? 111.666 139.057 138.730 1.00 43.92  ? 357 PHE B CZ  1 
ATOM   5929 N N   . GLY B 1 358 ? 111.963 133.263 137.653 1.00 35.50  ? 358 GLY B N   1 
ATOM   5930 C CA  . GLY B 1 358 ? 110.638 132.759 137.962 1.00 38.69  ? 358 GLY B CA  1 
ATOM   5931 C C   . GLY B 1 358 ? 110.612 131.965 139.251 1.00 43.48  ? 358 GLY B C   1 
ATOM   5932 O O   . GLY B 1 358 ? 109.674 132.079 140.041 1.00 47.40  ? 358 GLY B O   1 
ATOM   5933 N N   . VAL B 1 359 ? 111.636 131.142 139.478 1.00 41.58  ? 359 VAL B N   1 
ATOM   5934 C CA  . VAL B 1 359 ? 111.691 130.352 140.702 1.00 38.28  ? 359 VAL B CA  1 
ATOM   5935 C C   . VAL B 1 359 ? 111.976 131.242 141.904 1.00 40.52  ? 359 VAL B C   1 
ATOM   5936 O O   . VAL B 1 359 ? 111.391 131.062 142.977 1.00 50.35  ? 359 VAL B O   1 
ATOM   5937 C CB  . VAL B 1 359 ? 112.732 129.230 140.572 1.00 38.69  ? 359 VAL B CB  1 
ATOM   5938 C CG1 . VAL B 1 359 ? 112.767 128.420 141.833 1.00 41.12  ? 359 VAL B CG1 1 
ATOM   5939 C CG2 . VAL B 1 359 ? 112.398 128.343 139.400 1.00 50.06  ? 359 VAL B CG2 1 
ATOM   5940 N N   . ILE B 1 360 ? 112.881 132.210 141.751 1.00 39.52  ? 360 ILE B N   1 
ATOM   5941 C CA  . ILE B 1 360 ? 113.185 133.118 142.852 1.00 40.23  ? 360 ILE B CA  1 
ATOM   5942 C C   . ILE B 1 360 ? 111.949 133.912 143.248 1.00 42.78  ? 360 ILE B C   1 
ATOM   5943 O O   . ILE B 1 360 ? 111.645 134.064 144.435 1.00 53.50  ? 360 ILE B O   1 
ATOM   5944 C CB  . ILE B 1 360 ? 114.352 134.046 142.475 1.00 32.87  ? 360 ILE B CB  1 
ATOM   5945 C CG1 . ILE B 1 360 ? 115.644 133.251 142.362 1.00 36.76  ? 360 ILE B CG1 1 
ATOM   5946 C CG2 . ILE B 1 360 ? 114.515 135.132 143.504 1.00 35.35  ? 360 ILE B CG2 1 
ATOM   5947 C CD1 . ILE B 1 360 ? 116.847 134.105 142.105 1.00 43.33  ? 360 ILE B CD1 1 
ATOM   5948 N N   . GLY B 1 361 ? 111.210 134.421 142.263 1.00 38.60  ? 361 GLY B N   1 
ATOM   5949 C CA  . GLY B 1 361 ? 110.032 135.213 142.567 1.00 38.63  ? 361 GLY B CA  1 
ATOM   5950 C C   . GLY B 1 361 ? 108.935 134.421 143.245 1.00 41.11  ? 361 GLY B C   1 
ATOM   5951 O O   . GLY B 1 361 ? 108.074 134.996 143.913 1.00 48.49  ? 361 GLY B O   1 
ATOM   5952 N N   . PHE B 1 362 ? 108.942 133.100 143.081 1.00 42.94  ? 362 PHE B N   1 
ATOM   5953 C CA  . PHE B 1 362 ? 107.960 132.235 143.720 1.00 37.52  ? 362 PHE B CA  1 
ATOM   5954 C C   . PHE B 1 362 ? 108.446 131.701 145.057 1.00 42.00  ? 362 PHE B C   1 
ATOM   5955 O O   . PHE B 1 362 ? 107.657 131.589 145.999 1.00 50.84  ? 362 PHE B O   1 
ATOM   5956 C CB  . PHE B 1 362 ? 107.610 131.063 142.807 1.00 41.19  ? 362 PHE B CB  1 
ATOM   5957 C CG  . PHE B 1 362 ? 106.484 131.344 141.859 1.00 52.49  ? 362 PHE B CG  1 
ATOM   5958 C CD1 . PHE B 1 362 ? 105.194 131.488 142.325 1.00 53.32  ? 362 PHE B CD1 1 
ATOM   5959 C CD2 . PHE B 1 362 ? 106.715 131.456 140.503 1.00 48.21  ? 362 PHE B CD2 1 
ATOM   5960 C CE1 . PHE B 1 362 ? 104.158 131.743 141.458 1.00 54.27  ? 362 PHE B CE1 1 
ATOM   5961 C CE2 . PHE B 1 362 ? 105.683 131.711 139.633 1.00 43.94  ? 362 PHE B CE2 1 
ATOM   5962 C CZ  . PHE B 1 362 ? 104.403 131.854 140.112 1.00 46.28  ? 362 PHE B CZ  1 
ATOM   5963 N N   . LEU B 1 363 ? 109.732 131.357 145.157 1.00 46.74  ? 363 LEU B N   1 
ATOM   5964 C CA  . LEU B 1 363 ? 110.267 130.863 146.419 1.00 46.63  ? 363 LEU B CA  1 
ATOM   5965 C C   . LEU B 1 363 ? 110.221 131.932 147.498 1.00 49.33  ? 363 LEU B C   1 
ATOM   5966 O O   . LEU B 1 363 ? 110.013 131.618 148.673 1.00 57.44  ? 363 LEU B O   1 
ATOM   5967 C CB  . LEU B 1 363 ? 111.695 130.363 146.223 1.00 44.01  ? 363 LEU B CB  1 
ATOM   5968 C CG  . LEU B 1 363 ? 111.814 129.015 145.519 1.00 47.61  ? 363 LEU B CG  1 
ATOM   5969 C CD1 . LEU B 1 363 ? 113.221 128.481 145.633 1.00 50.43  ? 363 LEU B CD1 1 
ATOM   5970 C CD2 . LEU B 1 363 ? 110.818 128.026 146.084 1.00 41.08  ? 363 LEU B CD2 1 
ATOM   5971 N N   . GLU B 1 364 ? 110.421 133.195 147.126 1.00 42.13  ? 364 GLU B N   1 
ATOM   5972 C CA  . GLU B 1 364 ? 110.252 134.272 148.090 1.00 41.72  ? 364 GLU B CA  1 
ATOM   5973 C C   . GLU B 1 364 ? 108.808 134.384 148.552 1.00 51.17  ? 364 GLU B C   1 
ATOM   5974 O O   . GLU B 1 364 ? 108.549 134.868 149.658 1.00 63.00  ? 364 GLU B O   1 
ATOM   5975 C CB  . GLU B 1 364 ? 110.712 135.595 147.489 1.00 42.76  ? 364 GLU B CB  1 
ATOM   5976 C CG  . GLU B 1 364 ? 112.170 135.908 147.701 1.00 43.49  ? 364 GLU B CG  1 
ATOM   5977 C CD  . GLU B 1 364 ? 112.629 137.073 146.855 1.00 59.80  ? 364 GLU B CD  1 
ATOM   5978 O OE1 . GLU B 1 364 ? 111.884 137.468 145.935 1.00 66.66  ? 364 GLU B OE1 1 
ATOM   5979 O OE2 . GLU B 1 364 ? 113.729 137.600 147.110 1.00 61.16  ? 364 GLU B OE2 1 
ATOM   5980 N N   . ALA B 1 365 ? 107.855 133.967 147.719 1.00 47.83  ? 365 ALA B N   1 
ATOM   5981 C CA  . ALA B 1 365 ? 106.460 133.975 148.138 1.00 49.16  ? 365 ALA B CA  1 
ATOM   5982 C C   . ALA B 1 365 ? 106.150 132.812 149.070 1.00 53.70  ? 365 ALA B C   1 
ATOM   5983 O O   . ALA B 1 365 ? 105.373 132.965 150.016 1.00 62.76  ? 365 ALA B O   1 
ATOM   5984 C CB  . ALA B 1 365 ? 105.540 133.942 146.920 1.00 51.83  ? 365 ALA B CB  1 
ATOM   5985 N N   . ILE B 1 366 ? 106.736 131.642 148.815 1.00 47.16  ? 366 ILE B N   1 
ATOM   5986 C CA  . ILE B 1 366 ? 106.555 130.516 149.725 1.00 46.31  ? 366 ILE B CA  1 
ATOM   5987 C C   . ILE B 1 366 ? 107.228 130.801 151.058 1.00 54.17  ? 366 ILE B C   1 
ATOM   5988 O O   . ILE B 1 366 ? 106.709 130.442 152.121 1.00 63.96  ? 366 ILE B O   1 
ATOM   5989 C CB  . ILE B 1 366 ? 107.092 129.222 149.093 1.00 43.87  ? 366 ILE B CB  1 
ATOM   5990 C CG1 . ILE B 1 366 ? 106.520 129.031 147.696 1.00 50.33  ? 366 ILE B CG1 1 
ATOM   5991 C CG2 . ILE B 1 366 ? 106.725 128.036 149.944 1.00 43.02  ? 366 ILE B CG2 1 
ATOM   5992 C CD1 . ILE B 1 366 ? 107.190 127.929 146.932 1.00 54.11  ? 366 ILE B CD1 1 
ATOM   5993 N N   . VAL B 1 367 ? 108.397 131.441 151.025 1.00 46.57  ? 367 VAL B N   1 
ATOM   5994 C CA  . VAL B 1 367 ? 109.093 131.787 152.259 1.00 44.14  ? 367 VAL B CA  1 
ATOM   5995 C C   . VAL B 1 367 ? 108.240 132.721 153.104 1.00 55.07  ? 367 VAL B C   1 
ATOM   5996 O O   . VAL B 1 367 ? 108.112 132.540 154.320 1.00 66.67  ? 367 VAL B O   1 
ATOM   5997 C CB  . VAL B 1 367 ? 110.467 132.402 151.936 1.00 44.13  ? 367 VAL B CB  1 
ATOM   5998 C CG1 . VAL B 1 367 ? 110.906 133.340 153.038 1.00 48.73  ? 367 VAL B CG1 1 
ATOM   5999 C CG2 . VAL B 1 367 ? 111.494 131.313 151.732 1.00 49.17  ? 367 VAL B CG2 1 
ATOM   6000 N N   . CYS B 1 368 ? 107.632 133.727 152.474 1.00 56.95  ? 368 CYS B N   1 
ATOM   6001 C CA  . CYS B 1 368 ? 106.777 134.650 153.210 1.00 56.85  ? 368 CYS B CA  1 
ATOM   6002 C C   . CYS B 1 368 ? 105.556 133.942 153.780 1.00 61.70  ? 368 CYS B C   1 
ATOM   6003 O O   . CYS B 1 368 ? 105.123 134.240 154.897 1.00 67.41  ? 368 CYS B O   1 
ATOM   6004 C CB  . CYS B 1 368 ? 106.357 135.808 152.309 1.00 54.92  ? 368 CYS B CB  1 
ATOM   6005 S SG  . CYS B 1 368 ? 107.688 136.955 151.920 1.00 74.13  ? 368 CYS B SG  1 
ATOM   6006 N N   . ILE B 1 369 ? 104.978 133.007 153.025 1.00 54.20  ? 369 ILE B N   1 
ATOM   6007 C CA  . ILE B 1 369 ? 103.806 132.283 153.509 1.00 52.90  ? 369 ILE B CA  1 
ATOM   6008 C C   . ILE B 1 369 ? 104.165 131.433 154.720 1.00 61.42  ? 369 ILE B C   1 
ATOM   6009 O O   . ILE B 1 369 ? 103.455 131.434 155.732 1.00 68.52  ? 369 ILE B O   1 
ATOM   6010 C CB  . ILE B 1 369 ? 103.201 131.425 152.387 1.00 39.60  ? 369 ILE B CB  1 
ATOM   6011 C CG1 . ILE B 1 369 ? 102.541 132.305 151.333 1.00 49.59  ? 369 ILE B CG1 1 
ATOM   6012 C CG2 . ILE B 1 369 ? 102.184 130.464 152.952 1.00 52.55  ? 369 ILE B CG2 1 
ATOM   6013 C CD1 . ILE B 1 369 ? 101.983 131.526 150.175 1.00 59.82  ? 369 ILE B CD1 1 
ATOM   6014 N N   . LYS B 1 370 ? 105.271 130.694 154.636 1.00 60.63  ? 370 LYS B N   1 
ATOM   6015 C CA  . LYS B 1 370 ? 105.612 129.749 155.694 1.00 61.46  ? 370 LYS B CA  1 
ATOM   6016 C C   . LYS B 1 370 ? 105.941 130.464 156.998 1.00 63.53  ? 370 LYS B C   1 
ATOM   6017 O O   . LYS B 1 370 ? 105.500 130.040 158.071 1.00 61.20  ? 370 LYS B O   1 
ATOM   6018 C CB  . LYS B 1 370 ? 106.780 128.870 155.250 1.00 55.17  ? 370 LYS B CB  1 
ATOM   6019 C CG  . LYS B 1 370 ? 107.376 128.027 156.354 1.00 55.97  ? 370 LYS B CG  1 
ATOM   6020 C CD  . LYS B 1 370 ? 108.694 127.420 155.929 1.00 57.74  ? 370 LYS B CD  1 
ATOM   6021 C CE  . LYS B 1 370 ? 109.446 126.854 157.116 1.00 53.98  ? 370 LYS B CE  1 
ATOM   6022 N NZ  . LYS B 1 370 ? 108.664 125.810 157.818 1.00 60.53  ? 370 LYS B NZ  1 
ATOM   6023 N N   . PHE B 1 371 ? 106.709 131.548 156.929 1.00 64.70  ? 371 PHE B N   1 
ATOM   6024 C CA  . PHE B 1 371 ? 107.141 132.265 158.120 1.00 65.87  ? 371 PHE B CA  1 
ATOM   6025 C C   . PHE B 1 371 ? 106.198 133.386 158.529 1.00 69.07  ? 371 PHE B C   1 
ATOM   6026 O O   . PHE B 1 371 ? 106.402 133.985 159.589 1.00 73.44  ? 371 PHE B O   1 
ATOM   6027 C CB  . PHE B 1 371 ? 108.537 132.855 157.905 1.00 59.70  ? 371 PHE B CB  1 
ATOM   6028 C CG  . PHE B 1 371 ? 109.598 131.828 157.678 1.00 56.30  ? 371 PHE B CG  1 
ATOM   6029 C CD1 . PHE B 1 371 ? 109.810 130.821 158.594 1.00 56.22  ? 371 PHE B CD1 1 
ATOM   6030 C CD2 . PHE B 1 371 ? 110.387 131.871 156.549 1.00 58.20  ? 371 PHE B CD2 1 
ATOM   6031 C CE1 . PHE B 1 371 ? 110.789 129.879 158.384 1.00 59.58  ? 371 PHE B CE1 1 
ATOM   6032 C CE2 . PHE B 1 371 ? 111.365 130.929 156.337 1.00 57.48  ? 371 PHE B CE2 1 
ATOM   6033 C CZ  . PHE B 1 371 ? 111.566 129.933 157.254 1.00 56.25  ? 371 PHE B CZ  1 
ATOM   6034 N N   . GLY B 1 372 ? 105.183 133.689 157.728 1.00 76.65  ? 372 GLY B N   1 
ATOM   6035 C CA  . GLY B 1 372 ? 104.329 134.831 157.965 1.00 84.73  ? 372 GLY B CA  1 
ATOM   6036 C C   . GLY B 1 372 ? 102.985 134.546 158.590 1.00 86.85  ? 372 GLY B C   1 
ATOM   6037 O O   . GLY B 1 372 ? 102.148 135.454 158.653 1.00 91.28  ? 372 GLY B O   1 
ATOM   6038 N N   . GLN B 1 373 ? 102.742 133.325 159.061 1.00 87.31  ? 373 GLN B N   1 
ATOM   6039 C CA  . GLN B 1 373 ? 101.442 133.010 159.638 1.00 92.49  ? 373 GLN B CA  1 
ATOM   6040 C C   . GLN B 1 373 ? 101.207 133.713 160.968 1.00 94.48  ? 373 GLN B C   1 
ATOM   6041 O O   . GLN B 1 373 ? 100.061 133.778 161.423 1.00 95.72  ? 373 GLN B O   1 
ATOM   6042 C CB  . GLN B 1 373 ? 101.296 131.499 159.806 1.00 92.12  ? 373 GLN B CB  1 
ATOM   6043 C CG  . GLN B 1 373 ? 100.702 130.817 158.591 1.00 93.55  ? 373 GLN B CG  1 
ATOM   6044 C CD  . GLN B 1 373 ? 101.426 129.543 158.232 1.00 95.73  ? 373 GLN B CD  1 
ATOM   6045 O OE1 . GLN B 1 373 ? 102.335 129.114 158.940 1.00 97.56  ? 373 GLN B OE1 1 
ATOM   6046 N NE2 . GLN B 1 373 ? 101.034 128.932 157.120 1.00 90.83  ? 373 GLN B NE2 1 
ATOM   6047 N N   . ASP B 1 374 ? 102.258 134.234 161.604 1.00 98.57  ? 374 ASP B N   1 
ATOM   6048 C CA  . ASP B 1 374 ? 102.071 134.927 162.875 1.00 101.75 ? 374 ASP B CA  1 
ATOM   6049 C C   . ASP B 1 374 ? 101.308 136.234 162.688 1.00 101.81 ? 374 ASP B C   1 
ATOM   6050 O O   . ASP B 1 374 ? 100.428 136.564 163.491 1.00 102.27 ? 374 ASP B O   1 
ATOM   6051 C CB  . ASP B 1 374 ? 103.423 135.174 163.545 1.00 102.17 ? 374 ASP B CB  1 
ATOM   6052 C CG  . ASP B 1 374 ? 104.385 135.943 162.661 1.00 103.06 ? 374 ASP B CG  1 
ATOM   6053 O OD1 . ASP B 1 374 ? 104.100 137.116 162.340 1.00 102.93 ? 374 ASP B OD1 1 
ATOM   6054 O OD2 . ASP B 1 374 ? 105.432 135.374 162.288 1.00 98.34  ? 374 ASP B OD2 1 
ATOM   6055 N N   . LEU B 1 375 ? 101.631 136.992 161.639 1.00 97.90  ? 375 LEU B N   1 
ATOM   6056 C CA  . LEU B 1 375 ? 100.922 138.240 161.382 1.00 98.96  ? 375 LEU B CA  1 
ATOM   6057 C C   . LEU B 1 375 ? 99.547  138.004 160.772 1.00 99.11  ? 375 LEU B C   1 
ATOM   6058 O O   . LEU B 1 375 ? 98.652  138.841 160.934 1.00 99.42  ? 375 LEU B O   1 
ATOM   6059 C CB  . LEU B 1 375 ? 101.765 139.148 160.483 1.00 99.84  ? 375 LEU B CB  1 
ATOM   6060 C CG  . LEU B 1 375 ? 102.061 138.703 159.050 1.00 96.69  ? 375 LEU B CG  1 
ATOM   6061 C CD1 . LEU B 1 375 ? 101.125 139.371 158.067 1.00 95.49  ? 375 LEU B CD1 1 
ATOM   6062 C CD2 . LEU B 1 375 ? 103.501 139.012 158.699 1.00 95.00  ? 375 LEU B CD2 1 
ATOM   6063 N N   . PHE B 1 376 ? 99.360  136.888 160.072 1.00 106.16 ? 376 PHE B N   1 
ATOM   6064 C CA  . PHE B 1 376 ? 98.052  136.556 159.521 1.00 109.96 ? 376 PHE B CA  1 
ATOM   6065 C C   . PHE B 1 376 ? 97.069  136.244 160.645 1.00 109.40 ? 376 PHE B C   1 
ATOM   6066 O O   . PHE B 1 376 ? 97.261  135.288 161.401 1.00 107.30 ? 376 PHE B O   1 
ATOM   6067 C CB  . PHE B 1 376 ? 98.157  135.357 158.576 1.00 109.09 ? 376 PHE B CB  1 
ATOM   6068 C CG  . PHE B 1 376 ? 98.980  135.612 157.337 1.00 110.99 ? 376 PHE B CG  1 
ATOM   6069 C CD1 . PHE B 1 376 ? 99.002  136.863 156.742 1.00 111.28 ? 376 PHE B CD1 1 
ATOM   6070 C CD2 . PHE B 1 376 ? 99.703  134.583 156.747 1.00 107.46 ? 376 PHE B CD2 1 
ATOM   6071 C CE1 . PHE B 1 376 ? 99.753  137.089 155.598 1.00 113.00 ? 376 PHE B CE1 1 
ATOM   6072 C CE2 . PHE B 1 376 ? 100.451 134.804 155.604 1.00 104.54 ? 376 PHE B CE2 1 
ATOM   6073 C CZ  . PHE B 1 376 ? 100.476 136.057 155.029 1.00 105.33 ? 376 PHE B CZ  1 
ATOM   6074 N N   . SER B 1 377 ? 96.013  137.052 160.758 1.00 111.60 ? 377 SER B N   1 
ATOM   6075 C CA  . SER B 1 377 ? 94.986  136.822 161.768 1.00 108.07 ? 377 SER B CA  1 
ATOM   6076 C C   . SER B 1 377 ? 93.629  136.501 161.156 1.00 109.29 ? 377 SER B C   1 
ATOM   6077 O O   . SER B 1 377 ? 93.072  135.433 161.429 1.00 107.65 ? 377 SER B O   1 
ATOM   6078 C CB  . SER B 1 377 ? 94.887  138.044 162.690 1.00 107.13 ? 377 SER B CB  1 
ATOM   6079 O OG  . SER B 1 377 ? 94.814  139.242 161.937 1.00 108.51 ? 377 SER B OG  1 
ATOM   6080 N N   . LYS B 1 378 ? 93.080  137.389 160.333 1.00 107.31 ? 378 LYS B N   1 
ATOM   6081 C CA  . LYS B 1 378 ? 91.785  137.184 159.689 1.00 104.38 ? 378 LYS B CA  1 
ATOM   6082 C C   . LYS B 1 378 ? 91.924  137.621 158.227 1.00 103.63 ? 378 LYS B C   1 
ATOM   6083 O O   . LYS B 1 378 ? 91.200  138.474 157.715 1.00 100.59 ? 378 LYS B O   1 
ATOM   6084 C CB  . LYS B 1 378 ? 90.685  137.897 160.491 1.00 102.68 ? 378 LYS B CB  1 
ATOM   6085 C CG  . LYS B 1 378 ? 89.378  138.269 159.788 1.00 102.89 ? 378 LYS B CG  1 
ATOM   6086 C CD  . LYS B 1 378 ? 88.542  139.211 160.635 1.00 103.38 ? 378 LYS B CD  1 
ATOM   6087 C CE  . LYS B 1 378 ? 87.616  138.440 161.561 1.00 103.49 ? 378 LYS B CE  1 
ATOM   6088 N NZ  . LYS B 1 378 ? 87.099  139.293 162.666 1.00 104.44 ? 378 LYS B NZ  1 
ATOM   6089 N N   . THR B 1 379 ? 92.942  137.077 157.563 1.00 102.43 ? 379 THR B N   1 
ATOM   6090 C CA  . THR B 1 379 ? 93.277  137.489 156.207 1.00 102.18 ? 379 THR B CA  1 
ATOM   6091 C C   . THR B 1 379 ? 92.094  137.324 155.265 1.00 101.22 ? 379 THR B C   1 
ATOM   6092 O O   . THR B 1 379 ? 91.535  136.232 155.128 1.00 97.64  ? 379 THR B O   1 
ATOM   6093 C CB  . THR B 1 379 ? 94.454  136.668 155.688 1.00 98.14  ? 379 THR B CB  1 
ATOM   6094 O OG1 . THR B 1 379 ? 93.961  135.469 155.079 1.00 98.00  ? 379 THR B OG1 1 
ATOM   6095 C CG2 . THR B 1 379 ? 95.367  136.294 156.821 1.00 93.14  ? 379 THR B CG2 1 
ATOM   6096 N N   . GLN B 1 380 ? 91.724  138.417 154.604 1.00 96.71  ? 380 GLN B N   1 
ATOM   6097 C CA  . GLN B 1 380 ? 90.794  138.377 153.487 1.00 93.84  ? 380 GLN B CA  1 
ATOM   6098 C C   . GLN B 1 380 ? 91.623  138.305 152.212 1.00 98.33  ? 380 GLN B C   1 
ATOM   6099 O O   . GLN B 1 380 ? 92.329  139.257 151.864 1.00 96.76  ? 380 GLN B O   1 
ATOM   6100 C CB  . GLN B 1 380 ? 89.864  139.588 153.479 1.00 90.20  ? 380 GLN B CB  1 
ATOM   6101 C CG  . GLN B 1 380 ? 89.348  140.001 154.844 1.00 94.92  ? 380 GLN B CG  1 
ATOM   6102 C CD  . GLN B 1 380 ? 89.934  141.310 155.316 1.00 97.49  ? 380 GLN B CD  1 
ATOM   6103 O OE1 . GLN B 1 380 ? 90.967  141.753 154.818 1.00 99.55  ? 380 GLN B OE1 1 
ATOM   6104 N NE2 . GLN B 1 380 ? 89.273  141.943 156.278 1.00 92.67  ? 380 GLN B NE2 1 
ATOM   6105 N N   . ILE B 1 381 ? 91.547  137.164 151.532 1.00 91.73  ? 381 ILE B N   1 
ATOM   6106 C CA  . ILE B 1 381 ? 92.211  136.954 150.254 1.00 80.55  ? 381 ILE B CA  1 
ATOM   6107 C C   . ILE B 1 381 ? 91.323  137.562 149.181 1.00 79.70  ? 381 ILE B C   1 
ATOM   6108 O O   . ILE B 1 381 ? 91.633  137.508 147.986 1.00 83.09  ? 381 ILE B O   1 
ATOM   6109 C CB  . ILE B 1 381 ? 92.464  135.456 150.011 1.00 83.05  ? 381 ILE B CB  1 
ATOM   6110 C CG1 . ILE B 1 381 ? 93.521  135.245 148.932 1.00 82.21  ? 381 ILE B CG1 1 
ATOM   6111 C CG2 . ILE B 1 381 ? 91.172  134.753 149.639 1.00 85.25  ? 381 ILE B CG2 1 
ATOM   6112 C CD1 . ILE B 1 381 ? 94.249  133.937 149.058 1.00 86.91  ? 381 ILE B CD1 1 
ATOM   6113 N N   . LEU B 1 382 ? 90.204  138.148 149.613 1.00 78.19  ? 382 LEU B N   1 
ATOM   6114 C CA  . LEU B 1 382 ? 89.282  138.780 148.680 1.00 76.26  ? 382 LEU B CA  1 
ATOM   6115 C C   . LEU B 1 382 ? 89.947  139.941 147.958 1.00 80.18  ? 382 LEU B C   1 
ATOM   6116 O O   . LEU B 1 382 ? 89.729  140.142 146.759 1.00 87.87  ? 382 LEU B O   1 
ATOM   6117 C CB  . LEU B 1 382 ? 88.027  139.250 149.415 1.00 79.89  ? 382 LEU B CB  1 
ATOM   6118 C CG  . LEU B 1 382 ? 87.069  138.168 149.925 1.00 85.89  ? 382 LEU B CG  1 
ATOM   6119 C CD1 . LEU B 1 382 ? 86.828  137.104 148.865 1.00 86.34  ? 382 LEU B CD1 1 
ATOM   6120 C CD2 . LEU B 1 382 ? 87.551  137.549 151.231 1.00 81.27  ? 382 LEU B CD2 1 
ATOM   6121 N N   . TYR B 1 383 ? 90.764  140.721 148.665 1.00 75.36  ? 383 TYR B N   1 
ATOM   6122 C CA  . TYR B 1 383 ? 91.544  141.738 147.972 1.00 72.54  ? 383 TYR B CA  1 
ATOM   6123 C C   . TYR B 1 383 ? 92.681  141.109 147.182 1.00 71.51  ? 383 TYR B C   1 
ATOM   6124 O O   . TYR B 1 383 ? 93.074  141.628 146.134 1.00 75.18  ? 383 TYR B O   1 
ATOM   6125 C CB  . TYR B 1 383 ? 92.094  142.773 148.946 1.00 71.67  ? 383 TYR B CB  1 
ATOM   6126 C CG  . TYR B 1 383 ? 92.710  143.961 148.243 1.00 69.97  ? 383 TYR B CG  1 
ATOM   6127 C CD1 . TYR B 1 383 ? 91.931  145.029 147.818 1.00 69.61  ? 383 TYR B CD1 1 
ATOM   6128 C CD2 . TYR B 1 383 ? 94.068  144.001 147.983 1.00 69.41  ? 383 TYR B CD2 1 
ATOM   6129 C CE1 . TYR B 1 383 ? 92.492  146.110 147.173 1.00 68.66  ? 383 TYR B CE1 1 
ATOM   6130 C CE2 . TYR B 1 383 ? 94.636  145.073 147.339 1.00 72.23  ? 383 TYR B CE2 1 
ATOM   6131 C CZ  . TYR B 1 383 ? 93.846  146.123 146.936 1.00 71.98  ? 383 TYR B CZ  1 
ATOM   6132 O OH  . TYR B 1 383 ? 94.424  147.190 146.294 1.00 73.98  ? 383 TYR B OH  1 
ATOM   6133 N N   . VAL B 1 384 ? 93.237  139.999 147.669 1.00 80.63  ? 384 VAL B N   1 
ATOM   6134 C CA  . VAL B 1 384 ? 94.271  139.335 146.886 1.00 80.32  ? 384 VAL B CA  1 
ATOM   6135 C C   . VAL B 1 384 ? 93.685  138.803 145.587 1.00 75.89  ? 384 VAL B C   1 
ATOM   6136 O O   . VAL B 1 384 ? 94.341  138.822 144.543 1.00 71.66  ? 384 VAL B O   1 
ATOM   6137 C CB  . VAL B 1 384 ? 94.973  138.232 147.705 1.00 87.87  ? 384 VAL B CB  1 
ATOM   6138 C CG1 . VAL B 1 384 ? 95.770  137.312 146.795 1.00 81.97  ? 384 VAL B CG1 1 
ATOM   6139 C CG2 . VAL B 1 384 ? 95.906  138.844 148.732 1.00 84.59  ? 384 VAL B CG2 1 
ATOM   6140 N N   . VAL B 1 385 ? 92.439  138.341 145.614 1.00 83.87  ? 385 VAL B N   1 
ATOM   6141 C CA  . VAL B 1 385 ? 91.763  138.012 144.365 1.00 79.89  ? 385 VAL B CA  1 
ATOM   6142 C C   . VAL B 1 385 ? 91.500  139.279 143.565 1.00 78.46  ? 385 VAL B C   1 
ATOM   6143 O O   . VAL B 1 385 ? 91.473  139.259 142.328 1.00 87.58  ? 385 VAL B O   1 
ATOM   6144 C CB  . VAL B 1 385 ? 90.464  137.233 144.649 1.00 82.02  ? 385 VAL B CB  1 
ATOM   6145 C CG1 . VAL B 1 385 ? 89.558  137.213 143.427 1.00 78.74  ? 385 VAL B CG1 1 
ATOM   6146 C CG2 . VAL B 1 385 ? 90.794  135.822 145.098 1.00 80.87  ? 385 VAL B CG2 1 
ATOM   6147 N N   . LEU B 1 386 ? 91.337  140.408 144.255 1.00 77.42  ? 386 LEU B N   1 
ATOM   6148 C CA  . LEU B 1 386 ? 90.775  141.587 143.609 1.00 79.11  ? 386 LEU B CA  1 
ATOM   6149 C C   . LEU B 1 386 ? 91.676  142.122 142.503 1.00 81.77  ? 386 LEU B C   1 
ATOM   6150 O O   . LEU B 1 386 ? 91.179  142.460 141.423 1.00 82.20  ? 386 LEU B O   1 
ATOM   6151 C CB  . LEU B 1 386 ? 90.479  142.674 144.641 1.00 83.88  ? 386 LEU B CB  1 
ATOM   6152 C CG  . LEU B 1 386 ? 89.849  143.978 144.144 1.00 85.84  ? 386 LEU B CG  1 
ATOM   6153 C CD1 . LEU B 1 386 ? 88.849  144.487 145.164 1.00 86.63  ? 386 LEU B CD1 1 
ATOM   6154 C CD2 . LEU B 1 386 ? 90.901  145.040 143.879 1.00 78.44  ? 386 LEU B CD2 1 
ATOM   6155 N N   . TRP B 1 387 ? 93.002  142.214 142.724 1.00 76.49  ? 387 TRP B N   1 
ATOM   6156 C CA  . TRP B 1 387 ? 93.698  142.805 141.586 1.00 78.87  ? 387 TRP B CA  1 
ATOM   6157 C C   . TRP B 1 387 ? 93.882  141.806 140.458 1.00 83.85  ? 387 TRP B C   1 
ATOM   6158 O O   . TRP B 1 387 ? 94.205  142.218 139.342 1.00 87.42  ? 387 TRP B O   1 
ATOM   6159 C CB  . TRP B 1 387 ? 95.098  143.389 141.840 1.00 76.41  ? 387 TRP B CB  1 
ATOM   6160 C CG  . TRP B 1 387 ? 96.274  142.445 142.000 1.00 81.64  ? 387 TRP B CG  1 
ATOM   6161 C CD1 . TRP B 1 387 ? 97.361  142.433 141.183 1.00 85.67  ? 387 TRP B CD1 1 
ATOM   6162 C CD2 . TRP B 1 387 ? 96.645  141.627 143.125 1.00 91.27  ? 387 TRP B CD2 1 
ATOM   6163 N NE1 . TRP B 1 387 ? 98.290  141.535 141.612 1.00 80.73  ? 387 TRP B NE1 1 
ATOM   6164 C CE2 . TRP B 1 387 ? 97.896  141.043 142.820 1.00 85.72  ? 387 TRP B CE2 1 
ATOM   6165 C CE3 . TRP B 1 387 ? 96.025  141.278 144.320 1.00 95.57  ? 387 TRP B CE3 1 
ATOM   6166 C CZ2 . TRP B 1 387 ? 98.533  140.136 143.664 1.00 84.14  ? 387 TRP B CZ2 1 
ATOM   6167 C CZ3 . TRP B 1 387 ? 96.677  140.376 145.164 1.00 88.25  ? 387 TRP B CZ3 1 
ATOM   6168 C CH2 . TRP B 1 387 ? 97.905  139.816 144.824 1.00 89.42  ? 387 TRP B CH2 1 
ATOM   6169 N N   . LEU B 1 388 ? 93.698  140.513 140.719 1.00 73.65  ? 388 LEU B N   1 
ATOM   6170 C CA  . LEU B 1 388 ? 93.826  139.534 139.649 1.00 70.47  ? 388 LEU B CA  1 
ATOM   6171 C C   . LEU B 1 388 ? 92.779  139.781 138.574 1.00 74.73  ? 388 LEU B C   1 
ATOM   6172 O O   . LEU B 1 388 ? 93.064  139.660 137.379 1.00 83.03  ? 388 LEU B O   1 
ATOM   6173 C CB  . LEU B 1 388 ? 93.706  138.117 140.207 1.00 75.13  ? 388 LEU B CB  1 
ATOM   6174 C CG  . LEU B 1 388 ? 94.696  137.640 141.275 1.00 81.97  ? 388 LEU B CG  1 
ATOM   6175 C CD1 . LEU B 1 388 ? 94.935  136.140 141.134 1.00 82.12  ? 388 LEU B CD1 1 
ATOM   6176 C CD2 . LEU B 1 388 ? 96.013  138.404 141.255 1.00 78.24  ? 388 LEU B CD2 1 
ATOM   6177 N N   . LEU B 1 389 ? 91.557  140.129 138.979 1.00 72.12  ? 389 LEU B N   1 
ATOM   6178 C CA  . LEU B 1 389 ? 90.557  140.553 138.008 1.00 74.37  ? 389 LEU B CA  1 
ATOM   6179 C C   . LEU B 1 389 ? 90.825  141.970 137.515 1.00 79.29  ? 389 LEU B C   1 
ATOM   6180 O O   . LEU B 1 389 ? 90.624  142.264 136.333 1.00 87.03  ? 389 LEU B O   1 
ATOM   6181 C CB  . LEU B 1 389 ? 89.156  140.452 138.610 1.00 73.75  ? 389 LEU B CB  1 
ATOM   6182 C CG  . LEU B 1 389 ? 88.009  140.377 137.599 1.00 76.17  ? 389 LEU B CG  1 
ATOM   6183 C CD1 . LEU B 1 389 ? 87.035  139.279 137.977 1.00 77.34  ? 389 LEU B CD1 1 
ATOM   6184 C CD2 . LEU B 1 389 ? 87.287  141.710 137.484 1.00 77.07  ? 389 LEU B CD2 1 
ATOM   6185 N N   . CYS B 1 390 ? 91.281  142.859 138.402 1.00 74.91  ? 390 CYS B N   1 
ATOM   6186 C CA  . CYS B 1 390 ? 91.538  144.238 137.998 1.00 74.19  ? 390 CYS B CA  1 
ATOM   6187 C C   . CYS B 1 390 ? 92.674  144.331 136.991 1.00 80.71  ? 390 CYS B C   1 
ATOM   6188 O O   . CYS B 1 390 ? 92.644  145.192 136.106 1.00 87.61  ? 390 CYS B O   1 
ATOM   6189 C CB  . CYS B 1 390 ? 91.841  145.098 139.221 1.00 79.95  ? 390 CYS B CB  1 
ATOM   6190 S SG  . CYS B 1 390 ? 90.398  145.464 140.234 1.00 100.19 ? 390 CYS B SG  1 
ATOM   6191 N N   . VAL B 1 391 ? 93.686  143.471 137.112 1.00 69.38  ? 391 VAL B N   1 
ATOM   6192 C CA  . VAL B 1 391 ? 94.728  143.411 136.093 1.00 69.93  ? 391 VAL B CA  1 
ATOM   6193 C C   . VAL B 1 391 ? 94.177  142.812 134.804 1.00 69.90  ? 391 VAL B C   1 
ATOM   6194 O O   . VAL B 1 391 ? 94.486  143.281 133.702 1.00 69.74  ? 391 VAL B O   1 
ATOM   6195 C CB  . VAL B 1 391 ? 95.943  142.628 136.620 1.00 66.50  ? 391 VAL B CB  1 
ATOM   6196 C CG1 . VAL B 1 391 ? 96.892  142.301 135.497 1.00 68.78  ? 391 VAL B CG1 1 
ATOM   6197 C CG2 . VAL B 1 391 ? 96.663  143.432 137.680 1.00 62.86  ? 391 VAL B CG2 1 
ATOM   6198 N N   . ALA B 1 392 ? 93.344  141.775 134.917 1.00 71.05  ? 392 ALA B N   1 
ATOM   6199 C CA  . ALA B 1 392 ? 92.757  141.163 133.729 1.00 68.07  ? 392 ALA B CA  1 
ATOM   6200 C C   . ALA B 1 392 ? 91.836  142.132 133.004 1.00 72.57  ? 392 ALA B C   1 
ATOM   6201 O O   . ALA B 1 392 ? 91.802  142.158 131.769 1.00 78.57  ? 392 ALA B O   1 
ATOM   6202 C CB  . ALA B 1 392 ? 92.000  139.892 134.107 1.00 65.09  ? 392 ALA B CB  1 
ATOM   6203 N N   . PHE B 1 393 ? 91.066  142.924 133.751 1.00 82.52  ? 393 PHE B N   1 
ATOM   6204 C CA  . PHE B 1 393 ? 90.210  143.921 133.119 1.00 82.72  ? 393 PHE B CA  1 
ATOM   6205 C C   . PHE B 1 393 ? 91.038  144.979 132.404 1.00 81.76  ? 393 PHE B C   1 
ATOM   6206 O O   . PHE B 1 393 ? 90.678  145.423 131.309 1.00 85.68  ? 393 PHE B O   1 
ATOM   6207 C CB  . PHE B 1 393 ? 89.294  144.566 134.158 1.00 83.38  ? 393 PHE B CB  1 
ATOM   6208 C CG  . PHE B 1 393 ? 89.047  146.032 133.927 1.00 89.33  ? 393 PHE B CG  1 
ATOM   6209 C CD1 . PHE B 1 393 ? 88.149  146.455 132.962 1.00 86.59  ? 393 PHE B CD1 1 
ATOM   6210 C CD2 . PHE B 1 393 ? 89.711  146.988 134.679 1.00 89.87  ? 393 PHE B CD2 1 
ATOM   6211 C CE1 . PHE B 1 393 ? 87.920  147.803 132.750 1.00 84.68  ? 393 PHE B CE1 1 
ATOM   6212 C CE2 . PHE B 1 393 ? 89.487  148.337 134.471 1.00 88.77  ? 393 PHE B CE2 1 
ATOM   6213 C CZ  . PHE B 1 393 ? 88.590  148.745 133.506 1.00 86.28  ? 393 PHE B CZ  1 
ATOM   6214 N N   . THR B 1 394 ? 92.148  145.399 133.008 1.00 76.53  ? 394 THR B N   1 
ATOM   6215 C CA  . THR B 1 394 ? 92.966  146.438 132.394 1.00 81.60  ? 394 THR B CA  1 
ATOM   6216 C C   . THR B 1 394 ? 93.764  145.902 131.211 1.00 85.02  ? 394 THR B C   1 
ATOM   6217 O O   . THR B 1 394 ? 93.913  146.596 130.199 1.00 85.49  ? 394 THR B O   1 
ATOM   6218 C CB  . THR B 1 394 ? 93.897  147.062 133.431 1.00 82.35  ? 394 THR B CB  1 
ATOM   6219 O OG1 . THR B 1 394 ? 93.183  147.258 134.657 1.00 84.86  ? 394 THR B OG1 1 
ATOM   6220 C CG2 . THR B 1 394 ? 94.394  148.405 132.940 1.00 81.67  ? 394 THR B CG2 1 
ATOM   6221 N N   . THR B 1 395 ? 94.285  144.677 131.310 1.00 81.86  ? 395 THR B N   1 
ATOM   6222 C CA  . THR B 1 395 ? 94.959  144.077 130.164 1.00 79.04  ? 395 THR B CA  1 
ATOM   6223 C C   . THR B 1 395 ? 93.988  143.713 129.052 1.00 80.12  ? 395 THR B C   1 
ATOM   6224 O O   . THR B 1 395 ? 94.430  143.446 127.931 1.00 86.73  ? 395 THR B O   1 
ATOM   6225 C CB  . THR B 1 395 ? 95.749  142.835 130.588 1.00 79.47  ? 395 THR B CB  1 
ATOM   6226 O OG1 . THR B 1 395 ? 96.848  142.637 129.692 1.00 77.81  ? 395 THR B OG1 1 
ATOM   6227 C CG2 . THR B 1 395 ? 94.873  141.601 130.551 1.00 79.45  ? 395 THR B CG2 1 
ATOM   6228 N N   . PHE B 1 396 ? 92.687  143.689 129.332 1.00 87.23  ? 396 PHE B N   1 
ATOM   6229 C CA  . PHE B 1 396 ? 91.679  143.532 128.295 1.00 86.21  ? 396 PHE B CA  1 
ATOM   6230 C C   . PHE B 1 396 ? 91.316  144.865 127.655 1.00 89.38  ? 396 PHE B C   1 
ATOM   6231 O O   . PHE B 1 396 ? 91.056  144.921 126.450 1.00 94.19  ? 396 PHE B O   1 
ATOM   6232 C CB  . PHE B 1 396 ? 90.428  142.866 128.871 1.00 85.39  ? 396 PHE B CB  1 
ATOM   6233 C CG  . PHE B 1 396 ? 89.341  142.643 127.863 1.00 89.81  ? 396 PHE B CG  1 
ATOM   6234 C CD1 . PHE B 1 396 ? 89.342  141.513 127.066 1.00 90.16  ? 396 PHE B CD1 1 
ATOM   6235 C CD2 . PHE B 1 396 ? 88.312  143.558 127.721 1.00 91.12  ? 396 PHE B CD2 1 
ATOM   6236 C CE1 . PHE B 1 396 ? 88.342  141.304 126.139 1.00 91.06  ? 396 PHE B CE1 1 
ATOM   6237 C CE2 . PHE B 1 396 ? 87.311  143.355 126.796 1.00 90.75  ? 396 PHE B CE2 1 
ATOM   6238 C CZ  . PHE B 1 396 ? 87.325  142.226 126.004 1.00 91.47  ? 396 PHE B CZ  1 
ATOM   6239 N N   . LEU B 1 397 ? 91.283  145.942 128.442 1.00 90.63  ? 397 LEU B N   1 
ATOM   6240 C CA  . LEU B 1 397 ? 91.083  147.264 127.861 1.00 91.84  ? 397 LEU B CA  1 
ATOM   6241 C C   . LEU B 1 397 ? 92.294  147.703 127.053 1.00 92.57  ? 397 LEU B C   1 
ATOM   6242 O O   . LEU B 1 397 ? 92.156  148.492 126.113 1.00 97.41  ? 397 LEU B O   1 
ATOM   6243 C CB  . LEU B 1 397 ? 90.778  148.289 128.954 1.00 100.04 ? 397 LEU B CB  1 
ATOM   6244 C CG  . LEU B 1 397 ? 89.310  148.625 129.242 1.00 102.46 ? 397 LEU B CG  1 
ATOM   6245 C CD1 . LEU B 1 397 ? 89.212  149.845 130.146 1.00 96.78  ? 397 LEU B CD1 1 
ATOM   6246 C CD2 . LEU B 1 397 ? 88.526  148.847 127.958 1.00 95.82  ? 397 LEU B CD2 1 
ATOM   6247 N N   . CYS B 1 398 ? 93.484  147.213 127.406 1.00 90.39  ? 398 CYS B N   1 
ATOM   6248 C CA  . CYS B 1 398 ? 94.669  147.510 126.608 1.00 94.41  ? 398 CYS B CA  1 
ATOM   6249 C C   . CYS B 1 398 ? 94.518  146.978 125.190 1.00 93.77  ? 398 CYS B C   1 
ATOM   6250 O O   . CYS B 1 398 ? 94.979  147.605 124.230 1.00 97.23  ? 398 CYS B O   1 
ATOM   6251 C CB  . CYS B 1 398 ? 95.912  146.920 127.272 1.00 95.27  ? 398 CYS B CB  1 
ATOM   6252 S SG  . CYS B 1 398 ? 96.890  148.095 128.232 1.00 97.36  ? 398 CYS B SG  1 
ATOM   6253 N N   . LEU B 1 399 ? 93.882  145.817 125.039 1.00 100.29 ? 399 LEU B N   1 
ATOM   6254 C CA  . LEU B 1 399 ? 93.628  145.274 123.711 1.00 100.79 ? 399 LEU B CA  1 
ATOM   6255 C C   . LEU B 1 399 ? 92.726  146.204 122.912 1.00 104.59 ? 399 LEU B C   1 
ATOM   6256 O O   . LEU B 1 399 ? 93.099  146.682 121.835 1.00 107.75 ? 399 LEU B O   1 
ATOM   6257 C CB  . LEU B 1 399 ? 93.000  143.886 123.823 1.00 100.78 ? 399 LEU B CB  1 
ATOM   6258 C CG  . LEU B 1 399 ? 93.873  142.699 123.430 1.00 99.72  ? 399 LEU B CG  1 
ATOM   6259 C CD1 . LEU B 1 399 ? 94.935  142.458 124.484 1.00 96.64  ? 399 LEU B CD1 1 
ATOM   6260 C CD2 . LEU B 1 399 ? 93.022  141.461 123.219 1.00 102.45 ? 399 LEU B CD2 1 
ATOM   6261 N N   . TYR B 1 400 ? 91.529  146.480 123.435 1.00 118.58 ? 400 TYR B N   1 
ATOM   6262 C CA  . TYR B 1 400 ? 90.600  147.358 122.732 1.00 119.25 ? 400 TYR B CA  1 
ATOM   6263 C C   . TYR B 1 400 ? 91.184  148.752 122.558 1.00 120.04 ? 400 TYR B C   1 
ATOM   6264 O O   . TYR B 1 400 ? 91.023  149.372 121.501 1.00 125.49 ? 400 TYR B O   1 
ATOM   6265 C CB  . TYR B 1 400 ? 89.270  147.430 123.477 1.00 119.75 ? 400 TYR B CB  1 
ATOM   6266 C CG  . TYR B 1 400 ? 88.637  148.801 123.438 1.00 120.87 ? 400 TYR B CG  1 
ATOM   6267 C CD1 . TYR B 1 400 ? 87.849  149.193 122.366 1.00 122.14 ? 400 TYR B CD1 1 
ATOM   6268 C CD2 . TYR B 1 400 ? 88.823  149.704 124.477 1.00 119.77 ? 400 TYR B CD2 1 
ATOM   6269 C CE1 . TYR B 1 400 ? 87.270  150.446 122.326 1.00 122.60 ? 400 TYR B CE1 1 
ATOM   6270 C CE2 . TYR B 1 400 ? 88.250  150.957 124.446 1.00 121.09 ? 400 TYR B CE2 1 
ATOM   6271 C CZ  . TYR B 1 400 ? 87.474  151.323 123.369 1.00 121.54 ? 400 TYR B CZ  1 
ATOM   6272 O OH  . TYR B 1 400 ? 86.899  152.572 123.338 1.00 121.22 ? 400 TYR B OH  1 
ATOM   6273 N N   . GLY B 1 401 ? 91.861  149.264 123.586 1.00 118.66 ? 401 GLY B N   1 
ATOM   6274 C CA  . GLY B 1 401 ? 92.481  150.572 123.471 1.00 122.39 ? 401 GLY B CA  1 
ATOM   6275 C C   . GLY B 1 401 ? 93.498  150.645 122.352 1.00 124.29 ? 401 GLY B C   1 
ATOM   6276 O O   . GLY B 1 401 ? 93.818  151.734 121.868 1.00 124.86 ? 401 GLY B O   1 
ATOM   6277 N N   . MET B 1 402 ? 94.026  149.497 121.931 1.00 130.04 ? 402 MET B N   1 
ATOM   6278 C CA  . MET B 1 402 ? 94.912  149.436 120.776 1.00 129.81 ? 402 MET B CA  1 
ATOM   6279 C C   . MET B 1 402 ? 94.192  148.940 119.528 1.00 132.24 ? 402 MET B C   1 
ATOM   6280 O O   . MET B 1 402 ? 94.474  149.415 118.423 1.00 133.76 ? 402 MET B O   1 
ATOM   6281 C CB  . MET B 1 402 ? 96.112  148.536 121.079 1.00 129.74 ? 402 MET B CB  1 
ATOM   6282 C CG  . MET B 1 402 ? 97.284  148.724 120.129 1.00 134.11 ? 402 MET B CG  1 
ATOM   6283 S SD  . MET B 1 402 ? 97.376  150.398 119.466 1.00 143.56 ? 402 MET B SD  1 
ATOM   6284 C CE  . MET B 1 402 ? 98.567  150.179 118.147 1.00 133.61 ? 402 MET B CE  1 
ATOM   6285 N N   . ILE B 1 403 ? 93.268  147.989 119.681 1.00 134.59 ? 403 ILE B N   1 
ATOM   6286 C CA  . ILE B 1 403 ? 92.536  147.468 118.529 1.00 136.42 ? 403 ILE B CA  1 
ATOM   6287 C C   . ILE B 1 403 ? 91.675  148.563 117.910 1.00 136.73 ? 403 ILE B C   1 
ATOM   6288 O O   . ILE B 1 403 ? 91.648  148.740 116.686 1.00 137.01 ? 403 ILE B O   1 
ATOM   6289 C CB  . ILE B 1 403 ? 91.695  146.244 118.936 1.00 134.46 ? 403 ILE B CB  1 
ATOM   6290 C CG1 . ILE B 1 403 ? 92.549  144.974 118.883 1.00 132.58 ? 403 ILE B CG1 1 
ATOM   6291 C CG2 . ILE B 1 403 ? 90.467  146.107 118.046 1.00 134.45 ? 403 ILE B CG2 1 
ATOM   6292 C CD1 . ILE B 1 403 ? 91.787  143.711 119.205 1.00 133.43 ? 403 ILE B CD1 1 
ATOM   6293 N N   . TRP B 1 404 ? 90.960  149.315 118.748 1.00 144.53 ? 404 TRP B N   1 
ATOM   6294 C CA  . TRP B 1 404 ? 90.179  150.440 118.244 1.00 144.03 ? 404 TRP B CA  1 
ATOM   6295 C C   . TRP B 1 404 ? 91.084  151.538 117.700 1.00 144.63 ? 404 TRP B C   1 
ATOM   6296 O O   . TRP B 1 404 ? 90.763  152.168 116.686 1.00 145.37 ? 404 TRP B O   1 
ATOM   6297 C CB  . TRP B 1 404 ? 89.261  150.973 119.346 1.00 144.21 ? 404 TRP B CB  1 
ATOM   6298 C CG  . TRP B 1 404 ? 88.779  152.377 119.137 1.00 146.67 ? 404 TRP B CG  1 
ATOM   6299 C CD1 . TRP B 1 404 ? 87.589  152.761 118.593 1.00 146.38 ? 404 TRP B CD1 1 
ATOM   6300 C CD2 . TRP B 1 404 ? 89.454  153.585 119.517 1.00 148.21 ? 404 TRP B CD2 1 
ATOM   6301 N NE1 . TRP B 1 404 ? 87.493  154.132 118.583 1.00 147.62 ? 404 TRP B NE1 1 
ATOM   6302 C CE2 . TRP B 1 404 ? 88.624  154.661 119.147 1.00 148.76 ? 404 TRP B CE2 1 
ATOM   6303 C CE3 . TRP B 1 404 ? 90.685  153.859 120.122 1.00 144.92 ? 404 TRP B CE3 1 
ATOM   6304 C CZ2 . TRP B 1 404 ? 88.985  155.989 119.362 1.00 147.04 ? 404 TRP B CZ2 1 
ATOM   6305 C CZ3 . TRP B 1 404 ? 91.041  155.178 120.332 1.00 144.24 ? 404 TRP B CZ3 1 
ATOM   6306 C CH2 . TRP B 1 404 ? 90.194  156.226 119.955 1.00 145.61 ? 404 TRP B CH2 1 
ATOM   6307 N N   . TYR B 1 405 ? 92.219  151.784 118.359 1.00 147.08 ? 405 TYR B N   1 
ATOM   6308 C CA  . TYR B 1 405 ? 93.153  152.787 117.859 1.00 148.63 ? 405 TYR B CA  1 
ATOM   6309 C C   . TYR B 1 405 ? 93.826  152.334 116.571 1.00 149.30 ? 405 TYR B C   1 
ATOM   6310 O O   . TYR B 1 405 ? 94.213  153.172 115.749 1.00 148.60 ? 405 TYR B O   1 
ATOM   6311 C CB  . TYR B 1 405 ? 94.204  153.110 118.921 1.00 149.30 ? 405 TYR B CB  1 
ATOM   6312 C CG  . TYR B 1 405 ? 95.274  154.066 118.441 1.00 151.48 ? 405 TYR B CG  1 
ATOM   6313 C CD1 . TYR B 1 405 ? 94.970  155.390 118.153 1.00 151.76 ? 405 TYR B CD1 1 
ATOM   6314 C CD2 . TYR B 1 405 ? 96.584  153.642 118.266 1.00 149.99 ? 405 TYR B CD2 1 
ATOM   6315 C CE1 . TYR B 1 405 ? 95.943  156.267 117.711 1.00 151.26 ? 405 TYR B CE1 1 
ATOM   6316 C CE2 . TYR B 1 405 ? 97.564  154.511 117.824 1.00 149.39 ? 405 TYR B CE2 1 
ATOM   6317 C CZ  . TYR B 1 405 ? 97.237  155.822 117.548 1.00 150.72 ? 405 TYR B CZ  1 
ATOM   6318 O OH  . TYR B 1 405 ? 98.209  156.691 117.108 1.00 149.67 ? 405 TYR B OH  1 
ATOM   6319 N N   . ALA B 1 406 ? 93.977  151.021 116.379 1.00 151.80 ? 406 ALA B N   1 
ATOM   6320 C CA  . ALA B 1 406 ? 94.552  150.519 115.135 1.00 152.92 ? 406 ALA B CA  1 
ATOM   6321 C C   . ALA B 1 406 ? 93.673  150.869 113.940 1.00 154.51 ? 406 ALA B C   1 
ATOM   6322 O O   . ALA B 1 406 ? 94.180  151.211 112.866 1.00 152.00 ? 406 ALA B O   1 
ATOM   6323 C CB  . ALA B 1 406 ? 94.763  149.008 115.223 1.00 150.53 ? 406 ALA B CB  1 
ATOM   6324 N N   . GLU B 1 407 ? 92.350  150.778 114.106 1.00 162.03 ? 407 GLU B N   1 
ATOM   6325 C CA  . GLU B 1 407 ? 91.444  151.176 113.033 1.00 160.45 ? 407 GLU B CA  1 
ATOM   6326 C C   . GLU B 1 407 ? 91.575  152.661 112.724 1.00 160.55 ? 407 GLU B C   1 
ATOM   6327 O O   . GLU B 1 407 ? 91.606  153.059 111.554 1.00 160.60 ? 407 GLU B O   1 
ATOM   6328 C CB  . GLU B 1 407 ? 90.001  150.837 113.408 1.00 159.66 ? 407 GLU B CB  1 
ATOM   6329 C CG  . GLU B 1 407 ? 89.695  149.352 113.477 1.00 160.87 ? 407 GLU B CG  1 
ATOM   6330 C CD  . GLU B 1 407 ? 88.422  149.060 114.246 1.00 161.56 ? 407 GLU B CD  1 
ATOM   6331 O OE1 . GLU B 1 407 ? 87.787  150.020 114.730 1.00 162.01 ? 407 GLU B OE1 1 
ATOM   6332 O OE2 . GLU B 1 407 ? 88.053  147.873 114.363 1.00 161.79 ? 407 GLU B OE2 1 
ATOM   6333 N N   . HIS B 1 408 ? 91.655  153.494 113.757 1.00 157.17 ? 408 HIS B N   1 
ATOM   6334 C CA  . HIS B 1 408 ? 91.766  154.936 113.570 1.00 157.83 ? 408 HIS B CA  1 
ATOM   6335 C C   . HIS B 1 408 ? 93.212  155.346 113.311 1.00 156.68 ? 408 HIS B C   1 
ATOM   6336 O O   . HIS B 1 408 ? 93.831  154.902 112.344 1.00 155.95 ? 408 HIS B O   1 
ATOM   6337 C CB  . HIS B 1 408 ? 91.218  155.681 114.790 1.00 156.34 ? 408 HIS B CB  1 
ATOM   6338 C CG  . HIS B 1 408 ? 89.749  155.491 115.009 1.00 155.16 ? 408 HIS B CG  1 
ATOM   6339 N ND1 . HIS B 1 408 ? 89.191  154.263 115.291 1.00 154.90 ? 408 HIS B ND1 1 
ATOM   6340 C CD2 . HIS B 1 408 ? 88.723  156.374 114.985 1.00 155.26 ? 408 HIS B CD2 1 
ATOM   6341 C CE1 . HIS B 1 408 ? 87.885  154.398 115.433 1.00 154.97 ? 408 HIS B CE1 1 
ATOM   6342 N NE2 . HIS B 1 408 ? 87.575  155.669 115.252 1.00 155.35 ? 408 HIS B NE2 1 
HETATM 6343 O O2  . PSF C 2 .   ? 130.643 107.609 126.295 1.00 60.16  ? 501 PSF A O2  1 
HETATM 6344 O O1  . PSF C 2 .   ? 131.124 108.665 124.093 1.00 66.59  ? 501 PSF A O1  1 
HETATM 6345 P P   . PSF C 2 .   ? 129.851 108.216 125.003 1.00 74.60  ? 501 PSF A P   1 
HETATM 6346 O O4  . PSF C 2 .   ? 129.187 107.052 124.352 1.00 73.97  ? 501 PSF A O4  1 
HETATM 6347 O O3  . PSF C 2 .   ? 129.052 109.418 125.397 1.00 72.35  ? 501 PSF A O3  1 
HETATM 6348 C C2  . PSF C 2 .   ? 129.924 106.928 127.297 1.00 59.44  ? 501 PSF A C2  1 
HETATM 6349 C C3  . PSF C 2 .   ? 130.704 107.001 128.593 1.00 59.23  ? 501 PSF A C3  1 
HETATM 6350 O O11 . PSF C 2 .   ? 131.606 105.902 128.710 1.00 74.03  ? 501 PSF A O11 1 
HETATM 6351 O O12 . PSF C 2 .   ? 133.222 107.026 129.765 1.00 64.45  ? 501 PSF A O12 1 
HETATM 6352 C C1  . PSF C 2 .   ? 132.664 105.993 129.510 1.00 69.85  ? 501 PSF A C1  1 
HETATM 6353 C C4  . PSF C 2 .   ? 129.783 106.915 129.784 1.00 65.33  ? 501 PSF A C4  1 
HETATM 6354 C C5  . PSF C 2 .   ? 128.818 104.966 130.654 1.00 66.75  ? 501 PSF A C5  1 
HETATM 6355 O O51 . PSF C 2 .   ? 129.641 104.114 130.855 1.00 69.98  ? 501 PSF A O51 1 
HETATM 6356 O O52 . PSF C 2 .   ? 128.889 105.813 129.634 1.00 63.64  ? 501 PSF A O52 1 
HETATM 6357 C C6  . PSF C 2 .   ? 127.618 105.209 131.522 1.00 67.03  ? 501 PSF A C6  1 
HETATM 6358 C C7  . PSF C 2 .   ? 127.663 104.422 132.820 1.00 67.61  ? 501 PSF A C7  1 
HETATM 6359 C C13 . PSF C 2 .   ? 133.051 104.642 130.041 1.00 70.79  ? 501 PSF A C13 1 
HETATM 6360 C C14 . PSF C 2 .   ? 134.175 104.738 131.079 1.00 69.64  ? 501 PSF A C14 1 
HETATM 6361 C C15 . PSF C 2 .   ? 133.713 104.526 132.514 1.00 62.50  ? 501 PSF A C15 1 
HETATM 6362 N N   . PSF C 2 .   ? 132.978 109.849 122.685 1.00 61.72  ? 501 PSF A N   1 
HETATM 6363 C CA  . PSF C 2 .   ? 133.434 109.377 123.992 1.00 68.55  ? 501 PSF A CA  1 
HETATM 6364 C CB  . PSF C 2 .   ? 132.440 108.344 124.490 1.00 68.34  ? 501 PSF A CB  1 
HETATM 6365 C C   . PSF C 2 .   ? 134.861 108.796 123.962 1.00 71.61  ? 501 PSF A C   1 
HETATM 6366 O OT1 . PSF C 2 .   ? 135.646 109.350 123.164 1.00 69.94  ? 501 PSF A OT1 1 
HETATM 6367 O OT2 . PSF C 2 .   ? 135.124 107.841 124.716 1.00 68.04  ? 501 PSF A OT2 1 
HETATM 6368 C C8  . PSF C 2 .   ? 126.297 104.311 133.487 1.00 73.42  ? 501 PSF A C8  1 
HETATM 6369 C C9  . PSF C 2 .   ? 125.961 105.503 134.373 1.00 67.94  ? 501 PSF A C9  1 
HETATM 6370 C C10 . PSF C 2 .   ? 124.580 105.405 135.005 1.00 62.38  ? 501 PSF A C10 1 
HETATM 6371 C C16 . PSF C 2 .   ? 132.877 105.685 133.041 1.00 63.65  ? 501 PSF A C16 1 
HETATM 6372 C C17 . PSF C 2 .   ? 132.457 105.500 134.492 1.00 64.82  ? 501 PSF A C17 1 
HETATM 6373 O O2  . PSF D 2 .   ? 117.284 107.131 122.148 1.00 76.24  ? 502 PSF A O2  1 
HETATM 6374 O O1  . PSF D 2 .   ? 119.305 108.177 121.133 1.00 78.70  ? 502 PSF A O1  1 
HETATM 6375 P P   . PSF D 2 .   ? 117.984 107.329 120.687 1.00 90.17  ? 502 PSF A P   1 
HETATM 6376 O O4  . PSF D 2 .   ? 118.388 105.953 120.270 1.00 90.56  ? 502 PSF A O4  1 
HETATM 6377 O O3  . PSF D 2 .   ? 117.105 108.160 119.804 1.00 80.97  ? 502 PSF A O3  1 
HETATM 6378 C C2  . PSF D 2 .   ? 117.879 107.666 123.306 1.00 75.50  ? 502 PSF A C2  1 
HETATM 6379 C C3  . PSF D 2 .   ? 117.290 106.927 124.492 1.00 78.27  ? 502 PSF A C3  1 
HETATM 6380 O O11 . PSF D 2 .   ? 118.157 106.992 125.633 1.00 80.94  ? 502 PSF A O11 1 
HETATM 6381 O O12 . PSF D 2 .   ? 117.744 109.145 126.054 1.00 91.02  ? 502 PSF A O12 1 
HETATM 6382 C C1  . PSF D 2 .   ? 118.159 108.075 126.412 1.00 82.54  ? 502 PSF A C1  1 
HETATM 6383 C C4  . PSF D 2 .   ? 117.104 105.474 124.121 1.00 75.10  ? 502 PSF A C4  1 
HETATM 6384 C C5  . PSF D 2 .   ? 116.050 103.709 125.226 1.00 82.07  ? 502 PSF A C5  1 
HETATM 6385 O O51 . PSF D 2 .   ? 115.704 103.242 124.173 1.00 83.13  ? 502 PSF A O51 1 
HETATM 6386 O O52 . PSF D 2 .   ? 116.893 104.728 125.315 1.00 82.27  ? 502 PSF A O52 1 
HETATM 6387 C C6  . PSF D 2 .   ? 115.587 103.245 126.576 1.00 82.35  ? 502 PSF A C6  1 
HETATM 6388 C C7  . PSF D 2 .   ? 116.696 102.656 127.426 1.00 79.02  ? 502 PSF A C7  1 
HETATM 6389 C C13 . PSF D 2 .   ? 118.725 107.809 127.781 1.00 74.89  ? 502 PSF A C13 1 
HETATM 6390 C C14 . PSF D 2 .   ? 117.835 106.872 128.600 1.00 76.57  ? 502 PSF A C14 1 
HETATM 6391 C C15 . PSF D 2 .   ? 118.327 106.640 130.021 1.00 81.51  ? 502 PSF A C15 1 
HETATM 6392 N N   . PSF D 2 .   ? 120.957 109.007 119.090 1.00 83.38  ? 502 PSF A N   1 
HETATM 6393 C CA  . PSF D 2 .   ? 121.572 108.555 120.336 1.00 82.96  ? 502 PSF A CA  1 
HETATM 6394 C CB  . PSF D 2 .   ? 120.598 107.615 121.021 1.00 78.44  ? 502 PSF A CB  1 
HETATM 6395 C C   . PSF D 2 .   ? 122.939 107.877 120.117 1.00 86.18  ? 502 PSF A C   1 
HETATM 6396 O OT1 . PSF D 2 .   ? 123.937 108.544 120.463 1.00 88.78  ? 502 PSF A OT1 1 
HETATM 6397 O OT2 . PSF D 2 .   ? 122.952 106.735 119.620 1.00 84.31  ? 502 PSF A OT2 1 
HETATM 6398 C C8  . PSF D 2 .   ? 116.268 102.505 128.879 1.00 81.28  ? 502 PSF A C8  1 
HETATM 6399 C C9  . PSF D 2 .   ? 115.983 103.843 129.548 1.00 79.02  ? 502 PSF A C9  1 
HETATM 6400 C C10 . PSF D 2 .   ? 115.983 103.755 131.067 1.00 82.91  ? 502 PSF A C10 1 
HETATM 6401 C C16 . PSF D 2 .   ? 118.169 107.870 130.903 1.00 82.97  ? 502 PSF A C16 1 
HETATM 6402 C C17 . PSF D 2 .   ? 118.887 107.726 132.237 1.00 78.09  ? 502 PSF A C17 1 
HETATM 6403 C C1  . LBN E 3 .   ? 129.990 122.944 164.333 1.00 80.58  ? 503 LBN A C1  1 
HETATM 6404 N N1  . LBN E 3 .   ? 126.337 123.557 169.963 1.00 89.58  ? 503 LBN A N1  1 
HETATM 6405 P P1  . LBN E 3 .   ? 128.456 122.535 166.405 1.00 108.04 ? 503 LBN A P1  1 
HETATM 6406 C C2  . LBN E 3 .   ? 129.893 122.747 162.829 1.00 86.36  ? 503 LBN A C2  1 
HETATM 6407 C C3  . LBN E 3 .   ? 128.622 123.302 162.229 1.00 84.64  ? 503 LBN A C3  1 
HETATM 6408 C C4  . LBN E 3 .   ? 129.521 124.490 152.496 1.00 78.85  ? 503 LBN A C4  1 
HETATM 6409 C C5  . LBN E 3 .   ? 128.277 128.422 152.476 1.00 75.97  ? 503 LBN A C5  1 
HETATM 6410 C C6  . LBN E 3 .   ? 126.311 124.490 168.778 1.00 83.80  ? 503 LBN A C6  1 
HETATM 6411 O O1  . LBN E 3 .   ? 128.694 123.046 164.875 1.00 83.51  ? 503 LBN A O1  1 
HETATM 6412 C C7  . LBN E 3 .   ? 130.020 125.386 151.374 1.00 74.84  ? 503 LBN A C7  1 
HETATM 6413 C C8  . LBN E 3 .   ? 128.212 129.510 151.452 1.00 77.78  ? 503 LBN A C8  1 
HETATM 6414 C C9  . LBN E 3 .   ? 127.511 124.500 167.860 1.00 83.84  ? 503 LBN A C9  1 
HETATM 6415 O O2  . LBN E 3 .   ? 127.328 123.696 166.717 1.00 92.71  ? 503 LBN A O2  1 
HETATM 6416 C C10 . LBN E 3 .   ? 130.022 124.661 150.038 1.00 75.75  ? 503 LBN A C10 1 
HETATM 6417 C C11 . LBN E 3 .   ? 126.782 129.896 151.080 1.00 81.93  ? 503 LBN A C11 1 
HETATM 6418 C C12 . LBN E 3 .   ? 126.635 122.152 169.563 1.00 78.75  ? 503 LBN A C12 1 
HETATM 6419 O O3  . LBN E 3 .   ? 127.791 121.190 166.435 1.00 87.69  ? 503 LBN A O3  1 
HETATM 6420 C C13 . LBN E 3 .   ? 129.657 125.546 148.859 1.00 77.37  ? 503 LBN A C13 1 
HETATM 6421 C C14 . LBN E 3 .   ? 126.718 131.072 150.116 1.00 79.15  ? 503 LBN A C14 1 
HETATM 6422 C C15 . LBN E 3 .   ? 125.043 123.584 170.700 1.00 86.80  ? 503 LBN A C15 1 
HETATM 6423 O O4  . LBN E 3 .   ? 129.688 122.764 167.222 1.00 86.33  ? 503 LBN A O4  1 
HETATM 6424 C C16 . LBN E 3 .   ? 128.169 125.540 148.550 1.00 78.94  ? 503 LBN A C16 1 
HETATM 6425 C C17 . LBN E 3 .   ? 125.293 131.511 149.811 1.00 78.47  ? 503 LBN A C17 1 
HETATM 6426 C C18 . LBN E 3 .   ? 127.420 124.030 170.872 1.00 83.14  ? 503 LBN A C18 1 
HETATM 6427 C C19 . LBN E 3 .   ? 127.870 125.666 147.062 1.00 79.18  ? 503 LBN A C19 1 
HETATM 6428 C C20 . LBN E 3 .   ? 125.110 133.021 149.812 1.00 77.71  ? 503 LBN A C20 1 
HETATM 6429 C C21 . LBN E 3 .   ? 127.388 127.050 146.657 1.00 83.45  ? 503 LBN A C21 1 
HETATM 6430 C C22 . LBN E 3 .   ? 123.685 133.459 149.514 1.00 82.52  ? 503 LBN A C22 1 
HETATM 6431 C C23 . LBN E 3 .   ? 123.613 134.837 148.870 1.00 81.56  ? 503 LBN A C23 1 
HETATM 6432 C C24 . LBN E 3 .   ? 122.467 135.685 149.400 1.00 84.30  ? 503 LBN A C24 1 
HETATM 6433 C C25 . LBN E 3 .   ? 126.920 122.614 160.758 1.00 79.68  ? 503 LBN A C25 1 
HETATM 6434 O O5  . LBN E 3 .   ? 128.113 122.380 161.277 1.00 84.70  ? 503 LBN A O5  1 
HETATM 6435 C C26 . LBN E 3 .   ? 126.835 122.084 159.358 1.00 79.45  ? 503 LBN A C26 1 
HETATM 6436 O O6  . LBN E 3 .   ? 126.038 123.185 161.348 1.00 77.07  ? 503 LBN A O6  1 
HETATM 6437 C C27 . LBN E 3 .   ? 127.655 122.882 158.360 1.00 77.33  ? 503 LBN A C27 1 
HETATM 6438 C C28 . LBN E 3 .   ? 127.488 122.353 156.942 1.00 79.54  ? 503 LBN A C28 1 
HETATM 6439 C C29 . LBN E 3 .   ? 128.535 121.320 156.551 1.00 80.20  ? 503 LBN A C29 1 
HETATM 6440 C C30 . LBN E 3 .   ? 128.707 121.201 155.043 1.00 82.00  ? 503 LBN A C30 1 
HETATM 6441 C C31 . LBN E 3 .   ? 128.828 122.548 154.339 1.00 85.57  ? 503 LBN A C31 1 
HETATM 6442 C C32 . LBN E 3 .   ? 130.103 123.312 154.676 1.00 84.07  ? 503 LBN A C32 1 
HETATM 6443 C C33 . LBN E 3 .   ? 130.417 124.460 153.724 1.00 77.13  ? 503 LBN A C33 1 
HETATM 6444 C C34 . LBN E 3 .   ? 131.032 124.545 161.669 1.00 87.05  ? 503 LBN A C34 1 
HETATM 6445 O O7  . LBN E 3 .   ? 131.027 123.296 162.140 1.00 90.79  ? 503 LBN A O7  1 
HETATM 6446 C C35 . LBN E 3 .   ? 131.220 124.560 160.176 1.00 80.65  ? 503 LBN A C35 1 
HETATM 6447 O O8  . LBN E 3 .   ? 130.917 125.523 162.364 1.00 84.10  ? 503 LBN A O8  1 
HETATM 6448 C C36 . LBN E 3 .   ? 130.788 125.850 159.499 1.00 81.69  ? 503 LBN A C36 1 
HETATM 6449 C C37 . LBN E 3 .   ? 129.280 126.068 159.555 1.00 76.07  ? 503 LBN A C37 1 
HETATM 6450 C C38 . LBN E 3 .   ? 128.803 127.153 158.598 1.00 81.34  ? 503 LBN A C38 1 
HETATM 6451 C C39 . LBN E 3 .   ? 128.788 126.714 157.139 1.00 82.22  ? 503 LBN A C39 1 
HETATM 6452 C C40 . LBN E 3 .   ? 128.586 127.868 156.165 1.00 79.39  ? 503 LBN A C40 1 
HETATM 6453 C C41 . LBN E 3 .   ? 128.109 127.406 154.787 1.00 78.01  ? 503 LBN A C41 1 
HETATM 6454 C C42 . LBN E 3 .   ? 128.033 128.512 153.782 1.00 73.92  ? 503 LBN A C42 1 
HETATM 6455 C C1  . LBN F 3 .   ? 138.381 102.085 148.036 1.00 111.40 ? 504 LBN A C1  1 
HETATM 6456 N N1  . LBN F 3 .   ? 142.868 100.273 152.782 1.00 117.20 ? 504 LBN A N1  1 
HETATM 6457 P P1  . LBN F 3 .   ? 140.924 102.291 148.615 1.00 128.41 ? 504 LBN A P1  1 
HETATM 6458 C C2  . LBN F 3 .   ? 137.482 101.417 147.005 1.00 112.39 ? 504 LBN A C2  1 
HETATM 6459 C C3  . LBN F 3 .   ? 136.209 100.837 147.575 1.00 113.43 ? 504 LBN A C3  1 
HETATM 6460 C C6  . LBN F 3 .   ? 142.361 101.451 151.987 1.00 113.88 ? 504 LBN A C6  1 
HETATM 6461 O O1  . LBN F 3 .   ? 139.640 101.450 148.060 1.00 117.69 ? 504 LBN A O1  1 
HETATM 6462 C C9  . LBN F 3 .   ? 142.519 101.413 150.484 1.00 112.34 ? 504 LBN A C9  1 
HETATM 6463 O O2  . LBN F 3 .   ? 141.304 101.208 149.800 1.00 114.12 ? 504 LBN A O2  1 
HETATM 6464 C C12 . LBN F 3 .   ? 142.392 98.975  152.221 1.00 113.74 ? 504 LBN A C12 1 
HETATM 6465 O O3  . LBN F 3 .   ? 140.489 103.579 149.253 1.00 115.79 ? 504 LBN A O3  1 
HETATM 6466 C C15 . LBN F 3 .   ? 142.455 100.363 154.210 1.00 111.45 ? 504 LBN A C15 1 
HETATM 6467 O O4  . LBN F 3 .   ? 142.006 102.315 147.581 1.00 115.01 ? 504 LBN A O4  1 
HETATM 6468 C C18 . LBN F 3 .   ? 144.357 100.302 152.712 1.00 113.93 ? 504 LBN A C18 1 
HETATM 6469 C C25 . LBN F 3 .   ? 134.420 100.232 146.165 1.00 113.95 ? 504 LBN A C25 1 
HETATM 6470 O O5  . LBN F 3 .   ? 135.626 99.946  146.634 1.00 115.81 ? 504 LBN A O5  1 
HETATM 6471 C C26 . LBN F 3 .   ? 134.439 100.400 144.673 1.00 112.91 ? 504 LBN A C26 1 
HETATM 6472 O O6  . LBN F 3 .   ? 133.447 100.344 146.867 1.00 112.10 ? 504 LBN A O6  1 
HETATM 6473 C C27 . LBN F 3 .   ? 133.752 99.288  143.895 1.00 114.15 ? 504 LBN A C27 1 
HETATM 6474 C C28 . LBN F 3 .   ? 134.265 99.201  142.464 1.00 110.49 ? 504 LBN A C28 1 
HETATM 6475 C C29 . LBN F 3 .   ? 133.985 100.448 141.638 1.00 111.30 ? 504 LBN A C29 1 
HETATM 6476 C C30 . LBN F 3 .   ? 132.503 100.666 141.372 1.00 109.56 ? 504 LBN A C30 1 
HETATM 6477 C C34 . LBN F 3 .   ? 137.744 102.299 144.797 1.00 115.63 ? 504 LBN A C34 1 
HETATM 6478 O O7  . LBN F 3 .   ? 137.100 102.322 145.965 1.00 116.01 ? 504 LBN A O7  1 
HETATM 6479 C C35 . LBN F 3 .   ? 136.868 102.805 143.681 1.00 111.46 ? 504 LBN A C35 1 
HETATM 6480 O O8  . LBN F 3 .   ? 138.882 101.924 144.675 1.00 113.71 ? 504 LBN A O8  1 
HETATM 6481 C C36 . LBN F 3 .   ? 137.484 102.692 142.298 1.00 108.29 ? 504 LBN A C36 1 
HETATM 6482 C C37 . LBN F 3 .   ? 137.299 103.958 141.473 1.00 110.18 ? 504 LBN A C37 1 
HETATM 6483 C C38 . LBN F 3 .   ? 135.874 104.167 140.982 1.00 111.24 ? 504 LBN A C38 1 
HETATM 6484 C C39 . LBN F 3 .   ? 135.503 103.267 139.813 1.00 110.34 ? 504 LBN A C39 1 
HETATM 6485 C C40 . LBN F 3 .   ? 134.640 103.966 138.773 1.00 108.21 ? 504 LBN A C40 1 
HETATM 6486 C C41 . LBN F 3 .   ? 133.365 104.571 139.362 1.00 107.18 ? 504 LBN A C41 1 
HETATM 6487 C C1  . D12 G 4 .   ? 132.386 96.889  155.262 1.00 92.03  ? 505 D12 A C1  1 
HETATM 6488 C C2  . D12 G 4 .   ? 132.736 97.303  153.839 1.00 93.01  ? 505 D12 A C2  1 
HETATM 6489 C C3  . D12 G 4 .   ? 131.633 98.122  153.179 1.00 93.01  ? 505 D12 A C3  1 
HETATM 6490 C C4  . D12 G 4 .   ? 132.034 98.714  151.834 1.00 91.00  ? 505 D12 A C4  1 
HETATM 6491 C C5  . D12 G 4 .   ? 130.838 99.184  151.019 1.00 89.37  ? 505 D12 A C5  1 
HETATM 6492 C C6  . D12 G 4 .   ? 131.179 99.522  149.575 1.00 90.42  ? 505 D12 A C6  1 
HETATM 6493 C C7  . D12 G 4 .   ? 129.947 99.857  148.745 1.00 92.29  ? 505 D12 A C7  1 
HETATM 6494 C C8  . D12 G 4 .   ? 130.270 100.226 147.303 1.00 92.52  ? 505 D12 A C8  1 
HETATM 6495 C C9  . D12 G 4 .   ? 129.033 100.469 146.449 1.00 90.98  ? 505 D12 A C9  1 
HETATM 6496 C C10 . D12 G 4 .   ? 129.364 100.701 144.981 1.00 90.26  ? 505 D12 A C10 1 
HETATM 6497 C C11 . D12 G 4 .   ? 128.133 100.967 144.124 1.00 94.42  ? 505 D12 A C11 1 
HETATM 6498 C C12 . D12 G 4 .   ? 128.485 101.404 142.709 1.00 90.20  ? 505 D12 A C12 1 
HETATM 6499 C C01 . C14 H 5 .   ? 129.798 110.775 139.878 1.00 79.99  ? 506 C14 A C01 1 
HETATM 6500 C C02 . C14 H 5 .   ? 129.028 109.907 140.861 1.00 82.10  ? 506 C14 A C02 1 
HETATM 6501 C C03 . C14 H 5 .   ? 129.008 110.488 142.269 1.00 80.28  ? 506 C14 A C03 1 
HETATM 6502 C C04 . C14 H 5 .   ? 128.595 109.468 143.321 1.00 79.11  ? 506 C14 A C04 1 
HETATM 6503 C C05 . C14 H 5 .   ? 128.711 109.969 144.755 1.00 81.74  ? 506 C14 A C05 1 
HETATM 6504 C C06 . C14 H 5 .   ? 128.711 108.823 145.758 1.00 83.47  ? 506 C14 A C06 1 
HETATM 6505 C C07 . C14 H 5 .   ? 128.499 109.245 147.206 1.00 83.50  ? 506 C14 A C07 1 
HETATM 6506 C C08 . C14 H 5 .   ? 127.655 108.233 147.967 1.00 81.83  ? 506 C14 A C08 1 
HETATM 6507 C C09 . C14 H 5 .   ? 127.553 108.493 149.462 1.00 80.97  ? 506 C14 A C09 1 
HETATM 6508 C C10 . C14 H 5 .   ? 126.669 107.465 150.158 1.00 84.56  ? 506 C14 A C10 1 
HETATM 6509 C C11 . C14 H 5 .   ? 126.699 107.549 151.678 1.00 83.77  ? 506 C14 A C11 1 
HETATM 6510 C C12 . C14 H 5 .   ? 125.834 106.490 152.348 1.00 82.04  ? 506 C14 A C12 1 
HETATM 6511 C C13 . C14 H 5 .   ? 125.911 106.524 153.869 1.00 84.58  ? 506 C14 A C13 1 
HETATM 6512 C C14 . C14 H 5 .   ? 124.998 105.500 154.531 1.00 83.88  ? 506 C14 A C14 1 
HETATM 6513 C C1  . LBN I 3 .   ? 150.481 121.767 125.500 1.00 69.61  ? 507 LBN A C1  1 
HETATM 6514 N N1  . LBN I 3 .   ? 146.267 123.481 121.548 1.00 79.04  ? 507 LBN A N1  1 
HETATM 6515 P P1  . LBN I 3 .   ? 149.810 123.759 123.960 1.00 91.97  ? 507 LBN A P1  1 
HETATM 6516 C C2  . LBN I 3 .   ? 150.132 122.193 126.920 1.00 65.58  ? 507 LBN A C2  1 
HETATM 6517 C C3  . LBN I 3 .   ? 149.637 121.066 127.794 1.00 69.12  ? 507 LBN A C3  1 
HETATM 6518 C C4  . LBN I 3 .   ? 144.145 117.712 135.040 1.00 63.53  ? 507 LBN A C4  1 
HETATM 6519 C C5  . LBN I 3 .   ? 157.398 119.370 137.627 1.00 69.76  ? 507 LBN A C5  1 
HETATM 6520 C C6  . LBN I 3 .   ? 147.028 122.263 121.997 1.00 71.64  ? 507 LBN A C6  1 
HETATM 6521 O O1  . LBN I 3 .   ? 150.925 122.865 124.740 1.00 73.63  ? 507 LBN A O1  1 
HETATM 6522 C C7  . LBN I 3 .   ? 144.705 116.775 133.985 1.00 67.65  ? 507 LBN A C7  1 
HETATM 6523 C C8  . LBN I 3 .   ? 157.407 118.420 138.784 1.00 69.68  ? 507 LBN A C8  1 
HETATM 6524 C C9  . LBN I 3 .   ? 148.527 122.388 122.141 1.00 70.09  ? 507 LBN A C9  1 
HETATM 6525 O O2  . LBN I 3 .   ? 148.941 122.444 123.484 1.00 76.10  ? 507 LBN A O2  1 
HETATM 6526 C C10 . LBN I 3 .   ? 144.025 115.421 133.985 1.00 66.22  ? 507 LBN A C10 1 
HETATM 6527 C C11 . LBN I 3 .   ? 157.190 119.135 140.119 1.00 71.05  ? 507 LBN A C11 1 
HETATM 6528 C C12 . LBN I 3 .   ? 146.483 124.631 122.469 1.00 71.34  ? 507 LBN A C12 1 
HETATM 6529 O O3  . LBN I 3 .   ? 148.983 124.553 124.926 1.00 79.35  ? 507 LBN A O3  1 
HETATM 6530 C C13 . LBN I 3 .   ? 144.474 114.550 135.142 1.00 67.17  ? 507 LBN A C13 1 
HETATM 6531 C C14 . LBN I 3 .   ? 157.401 118.229 141.326 1.00 74.12  ? 507 LBN A C14 1 
HETATM 6532 C C15 . LBN I 3 .   ? 144.806 123.211 121.425 1.00 78.01  ? 507 LBN A C15 1 
HETATM 6533 O O4  . LBN I 3 .   ? 150.419 124.436 122.775 1.00 75.11  ? 507 LBN A O4  1 
HETATM 6534 C C16 . LBN I 3 .   ? 143.703 113.245 135.210 1.00 67.97  ? 507 LBN A C16 1 
HETATM 6535 C C17 . LBN I 3 .   ? 157.198 118.943 142.655 1.00 71.70  ? 507 LBN A C17 1 
HETATM 6536 C C18 . LBN I 3 .   ? 146.806 123.852 120.211 1.00 75.85  ? 507 LBN A C18 1 
HETATM 6537 C C19 . LBN I 3 .   ? 143.982 112.466 136.482 1.00 63.65  ? 507 LBN A C19 1 
HETATM 6538 C C20 . LBN I 3 .   ? 157.907 118.273 143.826 1.00 73.22  ? 507 LBN A C20 1 
HETATM 6539 C C21 . LBN I 3 .   ? 143.585 111.005 136.360 1.00 67.41  ? 507 LBN A C21 1 
HETATM 6540 C C22 . LBN I 3 .   ? 157.968 119.149 145.071 1.00 77.40  ? 507 LBN A C22 1 
HETATM 6541 C C23 . LBN I 3 .   ? 156.603 119.369 145.712 1.00 76.76  ? 507 LBN A C23 1 
HETATM 6542 C C24 . LBN I 3 .   ? 156.560 120.572 146.642 1.00 71.86  ? 507 LBN A C24 1 
HETATM 6543 C C25 . LBN I 3 .   ? 148.396 122.204 129.430 1.00 78.92  ? 507 LBN A C25 1 
HETATM 6544 O O5  . LBN I 3 .   ? 149.496 121.540 129.122 1.00 82.21  ? 507 LBN A O5  1 
HETATM 6545 C C26 . LBN I 3 .   ? 147.202 121.303 129.448 1.00 71.69  ? 507 LBN A C26 1 
HETATM 6546 O O6  . LBN I 3 .   ? 148.378 123.384 129.666 1.00 80.12  ? 507 LBN A O6  1 
HETATM 6547 C C27 . LBN I 3 .   ? 146.044 121.832 130.275 1.00 68.64  ? 507 LBN A C27 1 
HETATM 6548 C C28 . LBN I 3 .   ? 146.424 121.996 131.737 1.00 70.66  ? 507 LBN A C28 1 
HETATM 6549 C C29 . LBN I 3 .   ? 145.455 122.889 132.496 1.00 72.41  ? 507 LBN A C29 1 
HETATM 6550 C C30 . LBN I 3 .   ? 144.311 122.115 133.129 1.00 68.58  ? 507 LBN A C30 1 
HETATM 6551 C C31 . LBN I 3 .   ? 144.700 121.496 134.459 1.00 71.04  ? 507 LBN A C31 1 
HETATM 6552 C C32 . LBN I 3 .   ? 143.939 120.217 134.757 1.00 72.67  ? 507 LBN A C32 1 
HETATM 6553 C C33 . LBN I 3 .   ? 144.866 119.046 135.040 1.00 72.26  ? 507 LBN A C33 1 
HETATM 6554 C C34 . LBN I 3 .   ? 152.271 122.167 128.057 1.00 78.25  ? 507 LBN A C34 1 
HETATM 6555 O O7  . LBN I 3 .   ? 151.216 122.844 127.600 1.00 79.56  ? 507 LBN A O7  1 
HETATM 6556 C C35 . LBN I 3 .   ? 152.792 122.734 129.347 1.00 70.74  ? 507 LBN A C35 1 
HETATM 6557 O O8  . LBN I 3 .   ? 152.756 121.217 127.504 1.00 82.36  ? 507 LBN A O8  1 
HETATM 6558 C C36 . LBN I 3 .   ? 153.179 121.649 130.336 1.00 67.85  ? 507 LBN A C36 1 
HETATM 6559 C C37 . LBN I 3 .   ? 154.031 122.151 131.496 1.00 72.77  ? 507 LBN A C37 1 
HETATM 6560 C C38 . LBN I 3 .   ? 154.477 121.001 132.391 1.00 70.22  ? 507 LBN A C38 1 
HETATM 6561 C C39 . LBN I 3 .   ? 155.311 121.432 133.588 1.00 70.22  ? 507 LBN A C39 1 
HETATM 6562 C C40 . LBN I 3 .   ? 155.542 120.309 134.590 1.00 68.72  ? 507 LBN A C40 1 
HETATM 6563 C C41 . LBN I 3 .   ? 156.366 120.776 135.790 1.00 73.91  ? 507 LBN A C41 1 
HETATM 6564 C C42 . LBN I 3 .   ? 156.346 119.819 136.941 1.00 73.49  ? 507 LBN A C42 1 
HETATM 6565 C C1  . LBN J 3 .   ? 148.696 130.325 130.945 1.00 73.94  ? 508 LBN A C1  1 
HETATM 6566 N N1  . LBN J 3 .   ? 143.663 128.237 127.218 1.00 73.97  ? 508 LBN A N1  1 
HETATM 6567 P P1  . LBN J 3 .   ? 147.642 130.847 128.632 1.00 91.93  ? 508 LBN A P1  1 
HETATM 6568 C C2  . LBN J 3 .   ? 149.760 129.258 131.124 1.00 75.31  ? 508 LBN A C2  1 
HETATM 6569 C C3  . LBN J 3 .   ? 150.498 128.921 129.852 1.00 78.25  ? 508 LBN A C3  1 
HETATM 6570 C C4  . LBN J 3 .   ? 149.497 126.188 139.316 1.00 72.77  ? 508 LBN A C4  1 
HETATM 6571 C C6  . LBN J 3 .   ? 144.401 128.949 128.318 1.00 73.73  ? 508 LBN A C6  1 
HETATM 6572 O O1  . LBN J 3 .   ? 147.779 129.919 129.958 1.00 73.10  ? 508 LBN A O1  1 
HETATM 6573 C C7  . LBN J 3 .   ? 149.962 125.447 140.560 1.00 73.46  ? 508 LBN A C7  1 
HETATM 6574 C C9  . LBN J 3 .   ? 145.262 130.126 127.940 1.00 73.50  ? 508 LBN A C9  1 
HETATM 6575 O O2  . LBN J 3 .   ? 146.624 129.791 127.896 1.00 80.61  ? 508 LBN A O2  1 
HETATM 6576 C C10 . LBN J 3 .   ? 150.515 126.358 141.643 1.00 76.53  ? 508 LBN A C10 1 
HETATM 6577 C C12 . LBN J 3 .   ? 142.456 128.985 126.781 1.00 73.31  ? 508 LBN A C12 1 
HETATM 6578 O O3  . LBN J 3 .   ? 146.874 132.099 128.927 1.00 82.77  ? 508 LBN A O3  1 
HETATM 6579 C C13 . LBN J 3 .   ? 151.808 127.051 141.239 1.00 76.78  ? 508 LBN A C13 1 
HETATM 6580 C C15 . LBN J 3 .   ? 143.264 126.875 127.655 1.00 74.23  ? 508 LBN A C15 1 
HETATM 6581 O O4  . LBN J 3 .   ? 148.945 130.924 127.905 1.00 80.07  ? 508 LBN A O4  1 
HETATM 6582 C C16 . LBN J 3 .   ? 152.757 127.267 142.409 1.00 74.15  ? 508 LBN A C16 1 
HETATM 6583 C C18 . LBN J 3 .   ? 144.583 128.121 126.054 1.00 73.42  ? 508 LBN A C18 1 
HETATM 6584 C C19 . LBN J 3 .   ? 153.139 125.971 143.113 1.00 72.66  ? 508 LBN A C19 1 
HETATM 6585 C C21 . LBN J 3 .   ? 153.961 125.041 142.234 1.00 76.76  ? 508 LBN A C21 1 
HETATM 6586 C C25 . LBN J 3 .   ? 150.486 126.591 129.547 1.00 83.07  ? 508 LBN A C25 1 
HETATM 6587 O O5  . LBN J 3 .   ? 151.124 127.656 130.003 1.00 87.66  ? 508 LBN A O5  1 
HETATM 6588 C C26 . LBN J 3 .   ? 150.713 125.404 130.433 1.00 75.00  ? 508 LBN A C26 1 
HETATM 6589 O O6  . LBN J 3 .   ? 149.810 126.600 128.550 1.00 81.19  ? 508 LBN A O6  1 
HETATM 6590 C C27 . LBN J 3 .   ? 150.426 125.661 131.903 1.00 74.48  ? 508 LBN A C27 1 
HETATM 6591 C C28 . LBN J 3 .   ? 150.767 124.449 132.756 1.00 75.03  ? 508 LBN A C28 1 
HETATM 6592 C C29 . LBN J 3 .   ? 149.698 124.134 133.790 1.00 75.64  ? 508 LBN A C29 1 
HETATM 6593 C C30 . LBN J 3 .   ? 149.723 125.084 134.976 1.00 73.78  ? 508 LBN A C30 1 
HETATM 6594 C C31 . LBN J 3 .   ? 148.423 125.067 135.769 1.00 77.07  ? 508 LBN A C31 1 
HETATM 6595 C C32 . LBN J 3 .   ? 148.458 125.953 137.005 1.00 73.48  ? 508 LBN A C32 1 
HETATM 6596 C C33 . LBN J 3 .   ? 149.023 125.241 138.225 1.00 75.88  ? 508 LBN A C33 1 
HETATM 6597 C C34 . LBN J 3 .   ? 150.457 129.506 133.396 1.00 75.18  ? 508 LBN A C34 1 
HETATM 6598 O O7  . LBN J 3 .   ? 150.728 129.650 132.101 1.00 76.10  ? 508 LBN A O7  1 
HETATM 6599 C C35 . LBN J 3 .   ? 151.676 129.765 134.233 1.00 78.92  ? 508 LBN A C35 1 
HETATM 6600 O O8  . LBN J 3 .   ? 149.375 129.210 133.827 1.00 78.12  ? 508 LBN A O8  1 
HETATM 6601 C C36 . LBN J 3 .   ? 151.502 129.401 135.699 1.00 80.38  ? 508 LBN A C36 1 
HETATM 6602 C C37 . LBN J 3 .   ? 151.886 127.954 135.983 1.00 75.24  ? 508 LBN A C37 1 
HETATM 6603 C C1  . LBN K 3 .   ? 125.082 108.629 157.671 1.00 80.61  ? 509 LBN A C1  1 
HETATM 6604 N N1  . LBN K 3 .   ? 123.497 113.870 160.417 1.00 81.45  ? 509 LBN A N1  1 
HETATM 6605 P P1  . LBN K 3 .   ? 122.952 109.892 158.494 1.00 108.02 ? 509 LBN A P1  1 
HETATM 6606 C C2  . LBN K 3 .   ? 125.764 109.212 156.442 1.00 87.38  ? 509 LBN A C2  1 
HETATM 6607 C C3  . LBN K 3 .   ? 124.827 109.883 155.463 1.00 87.42  ? 509 LBN A C3  1 
HETATM 6608 C C4  . LBN K 3 .   ? 127.138 114.058 149.136 1.00 85.06  ? 509 LBN A C4  1 
HETATM 6609 C C5  . LBN K 3 .   ? 133.350 113.846 150.854 1.00 83.74  ? 509 LBN A C5  1 
HETATM 6610 C C6  . LBN K 3 .   ? 123.408 112.490 161.012 1.00 81.74  ? 509 LBN A C6  1 
HETATM 6611 O O1  . LBN K 3 .   ? 124.567 109.663 158.477 1.00 85.94  ? 509 LBN A O1  1 
HETATM 6612 C C7  . LBN K 3 .   ? 126.666 114.249 147.700 1.00 79.72  ? 509 LBN A C7  1 
HETATM 6613 C C8  . LBN K 3 .   ? 134.284 115.005 150.984 1.00 81.07  ? 509 LBN A C8  1 
HETATM 6614 C C9  . LBN K 3 .   ? 122.382 111.536 160.443 1.00 86.39  ? 509 LBN A C9  1 
HETATM 6615 O O2  . LBN K 3 .   ? 122.936 110.291 160.092 1.00 93.54  ? 509 LBN A O2  1 
HETATM 6616 C C10 . LBN K 3 .   ? 127.801 114.566 146.736 1.00 81.24  ? 509 LBN A C10 1 
HETATM 6617 C C11 . LBN K 3 .   ? 135.711 114.538 151.279 1.00 80.97  ? 509 LBN A C11 1 
HETATM 6618 C C12 . LBN K 3 .   ? 124.480 113.939 159.305 1.00 76.24  ? 509 LBN A C12 1 
HETATM 6619 O O3  . LBN K 3 .   ? 122.570 111.098 157.687 1.00 85.42  ? 509 LBN A O3  1 
HETATM 6620 C C13 . LBN K 3 .   ? 128.572 115.822 147.128 1.00 83.52  ? 509 LBN A C13 1 
HETATM 6621 C C14 . LBN K 3 .   ? 136.581 115.613 151.912 1.00 76.28  ? 509 LBN A C14 1 
HETATM 6622 C C15 . LBN K 3 .   ? 122.169 114.326 159.929 1.00 87.81  ? 509 LBN A C15 1 
HETATM 6623 O O4  . LBN K 3 .   ? 122.232 108.600 158.270 1.00 88.81  ? 509 LBN A O4  1 
HETATM 6624 C C16 . LBN K 3 .   ? 129.684 116.214 146.165 1.00 78.97  ? 509 LBN A C16 1 
HETATM 6625 C C17 . LBN K 3 .   ? 137.308 115.136 153.159 1.00 75.45  ? 509 LBN A C17 1 
HETATM 6626 C C18 . LBN K 3 .   ? 123.940 114.785 161.503 1.00 78.56  ? 509 LBN A C18 1 
HETATM 6627 C C19 . LBN K 3 .   ? 130.522 115.033 145.697 1.00 82.43  ? 509 LBN A C19 1 
HETATM 6628 C C20 . LBN K 3 .   ? 137.037 116.017 154.372 1.00 85.76  ? 509 LBN A C20 1 
HETATM 6629 C C21 . LBN K 3 .   ? 131.400 114.444 146.790 1.00 83.59  ? 509 LBN A C21 1 
HETATM 6630 C C22 . LBN K 3 .   ? 135.588 115.964 154.839 1.00 86.50  ? 509 LBN A C22 1 
HETATM 6631 C C23 . LBN K 3 .   ? 135.207 117.072 155.812 1.00 80.75  ? 509 LBN A C23 1 
HETATM 6632 C C24 . LBN K 3 .   ? 136.142 117.143 157.007 1.00 77.69  ? 509 LBN A C24 1 
HETATM 6633 C C25 . LBN K 3 .   ? 122.934 109.348 154.161 1.00 87.89  ? 509 LBN A C25 1 
HETATM 6634 O O5  . LBN K 3 .   ? 123.937 108.920 154.914 1.00 88.90  ? 509 LBN A O5  1 
HETATM 6635 C C26 . LBN K 3 .   ? 123.428 110.069 152.941 1.00 84.71  ? 509 LBN A C26 1 
HETATM 6636 O O6  . LBN K 3 .   ? 121.774 109.169 154.436 1.00 86.75  ? 509 LBN A O6  1 
HETATM 6637 C C27 . LBN K 3 .   ? 122.413 111.025 152.334 1.00 83.68  ? 509 LBN A C27 1 
HETATM 6638 C C28 . LBN K 3 .   ? 122.791 111.422 150.914 1.00 79.76  ? 509 LBN A C28 1 
HETATM 6639 C C29 . LBN K 3 .   ? 124.250 111.830 150.768 1.00 79.81  ? 509 LBN A C29 1 
HETATM 6640 C C30 . LBN K 3 .   ? 124.577 113.139 151.471 1.00 83.34  ? 509 LBN A C30 1 
HETATM 6641 C C31 . LBN K 3 .   ? 126.063 113.294 151.770 1.00 87.10  ? 509 LBN A C31 1 
HETATM 6642 C C32 . LBN K 3 .   ? 126.589 114.707 151.556 1.00 84.14  ? 509 LBN A C32 1 
HETATM 6643 C C33 . LBN K 3 .   ? 126.601 115.119 150.089 1.00 87.24  ? 509 LBN A C33 1 
HETATM 6644 C C34 . LBN K 3 .   ? 127.919 110.189 156.153 1.00 87.37  ? 509 LBN A C34 1 
HETATM 6645 O O7  . LBN K 3 .   ? 126.761 110.170 156.806 1.00 89.48  ? 509 LBN A O7  1 
HETATM 6646 C C35 . LBN K 3 .   ? 128.093 111.467 155.383 1.00 84.90  ? 509 LBN A C35 1 
HETATM 6647 O O8  . LBN K 3 .   ? 128.713 109.287 156.191 1.00 85.11  ? 509 LBN A O8  1 
HETATM 6648 C C36 . LBN K 3 .   ? 128.181 111.271 153.880 1.00 79.68  ? 509 LBN A C36 1 
HETATM 6649 C C37 . LBN K 3 .   ? 129.625 111.233 153.400 1.00 81.12  ? 509 LBN A C37 1 
HETATM 6650 C C38 . LBN K 3 .   ? 129.913 112.237 152.293 1.00 80.44  ? 509 LBN A C38 1 
HETATM 6651 C C39 . LBN K 3 .   ? 129.765 111.659 150.892 1.00 84.89  ? 509 LBN A C39 1 
HETATM 6652 C C40 . LBN K 3 .   ? 130.465 112.504 149.837 1.00 85.66  ? 509 LBN A C40 1 
HETATM 6653 C C41 . LBN K 3 .   ? 131.935 112.124 149.664 1.00 86.96  ? 509 LBN A C41 1 
HETATM 6654 C C42 . LBN K 3 .   ? 132.861 113.297 149.744 1.00 84.33  ? 509 LBN A C42 1 
HETATM 6655 C C1  . T7X L 6 .   ? 121.192 123.282 127.037 1.00 69.17  ? 510 T7X A C1  1 
HETATM 6656 O O1  . T7X L 6 .   ? 120.071 122.420 127.088 1.00 77.35  ? 510 T7X A O1  1 
HETATM 6657 P P1  . T7X L 6 .   ? 119.728 121.169 126.083 1.00 86.73  ? 510 T7X A P1  1 
HETATM 6658 C C2  . T7X L 6 .   ? 122.088 122.940 128.218 1.00 61.29  ? 510 T7X A C2  1 
HETATM 6659 O O2  . T7X L 6 .   ? 121.442 123.426 129.362 1.00 62.19  ? 510 T7X A O2  1 
HETATM 6660 C C3  . T7X L 6 .   ? 123.475 123.565 128.104 1.00 66.03  ? 510 T7X A C3  1 
HETATM 6661 O O3  . T7X L 6 .   ? 124.362 122.537 127.726 1.00 71.96  ? 510 T7X A O3  1 
HETATM 6662 C C4  . T7X L 6 .   ? 123.548 124.755 127.149 1.00 72.03  ? 510 T7X A C4  1 
HETATM 6663 O O4  . T7X L 6 .   ? 122.878 125.880 127.685 1.00 79.65  ? 510 T7X A O4  1 
HETATM 6664 C C5  . T7X L 6 .   ? 122.968 124.474 125.760 1.00 71.91  ? 510 T7X A C5  1 
HETATM 6665 O O5  . T7X L 6 .   ? 123.980 124.163 124.833 1.00 77.54  ? 510 T7X A O5  1 
HETATM 6666 C C6  . T7X L 6 .   ? 121.958 123.329 125.718 1.00 71.24  ? 510 T7X A C6  1 
HETATM 6667 O O6  . T7X L 6 .   ? 122.591 122.101 125.465 1.00 82.30  ? 510 T7X A O6  1 
HETATM 6668 C C7  . T7X L 6 .   ? 118.659 120.976 128.467 1.00 69.28  ? 510 T7X A C7  1 
HETATM 6669 C C8  . T7X L 6 .   ? 117.723 120.222 129.391 1.00 72.76  ? 510 T7X A C8  1 
HETATM 6670 C C9  . T7X L 6 .   ? 116.597 121.034 129.980 1.00 73.04  ? 510 T7X A C9  1 
HETATM 6671 C C10 . T7X L 6 .   ? 117.820 117.960 128.729 1.00 73.34  ? 510 T7X A C10 1 
HETATM 6672 C C11 . T7X L 6 .   ? 114.856 119.853 130.997 1.00 72.55  ? 510 T7X A C11 1 
HETATM 6673 O O11 . T7X L 6 .   ? 120.933 120.349 125.756 1.00 81.43  ? 510 T7X A O11 1 
HETATM 6674 C C12 . T7X L 6 .   ? 117.190 116.947 127.822 1.00 71.21  ? 510 T7X A C12 1 
HETATM 6675 O O12 . T7X L 6 .   ? 118.825 121.633 124.984 1.00 77.81  ? 510 T7X A O12 1 
HETATM 6676 C C13 . T7X L 6 .   ? 115.691 116.835 128.012 1.00 66.78  ? 510 T7X A C13 1 
HETATM 6677 O O13 . T7X L 6 .   ? 118.840 120.371 127.209 1.00 63.40  ? 510 T7X A O13 1 
HETATM 6678 C C14 . T7X L 6 .   ? 115.377 116.157 129.341 1.00 67.03  ? 510 T7X A C14 1 
HETATM 6679 C C15 . T7X L 6 .   ? 114.403 115.038 129.177 1.00 74.72  ? 510 T7X A C15 1 
HETATM 6680 C C16 . T7X L 6 .   ? 113.328 114.790 129.917 1.00 75.15  ? 510 T7X A C16 1 
HETATM 6681 O O16 . T7X L 6 .   ? 117.145 119.099 128.724 1.00 72.21  ? 510 T7X A O16 1 
HETATM 6682 C C17 . T7X L 6 .   ? 112.352 113.662 129.765 1.00 73.14  ? 510 T7X A C17 1 
HETATM 6683 O O17 . T7X L 6 .   ? 118.813 117.780 129.384 1.00 79.36  ? 510 T7X A O17 1 
HETATM 6684 C C18 . T7X L 6 .   ? 112.851 112.479 130.544 1.00 71.84  ? 510 T7X A C18 1 
HETATM 6685 O O18 . T7X L 6 .   ? 116.077 120.345 131.103 1.00 73.30  ? 510 T7X A O18 1 
HETATM 6686 C C19 . T7X L 6 .   ? 114.053 111.917 130.442 1.00 73.54  ? 510 T7X A C19 1 
HETATM 6687 O O19 . T7X L 6 .   ? 114.046 120.269 130.211 1.00 72.74  ? 510 T7X A O19 1 
HETATM 6688 C C20 . T7X L 6 .   ? 114.604 110.743 131.196 1.00 76.07  ? 510 T7X A C20 1 
HETATM 6689 C C21 . T7X L 6 .   ? 115.845 111.143 131.939 1.00 79.24  ? 510 T7X A C21 1 
HETATM 6690 C C22 . T7X L 6 .   ? 116.398 112.352 131.905 1.00 73.50  ? 510 T7X A C22 1 
HETATM 6691 C C23 . T7X L 6 .   ? 117.639 112.752 132.647 1.00 69.58  ? 510 T7X A C23 1 
HETATM 6692 C C24 . T7X L 6 .   ? 117.456 114.074 133.332 1.00 72.11  ? 510 T7X A C24 1 
HETATM 6693 C C25 . T7X L 6 .   ? 116.292 114.637 133.637 1.00 73.47  ? 510 T7X A C25 1 
HETATM 6694 C C26 . T7X L 6 .   ? 116.138 115.960 134.319 1.00 73.02  ? 510 T7X A C26 1 
HETATM 6695 C C27 . T7X L 6 .   ? 115.546 115.835 135.722 1.00 68.24  ? 510 T7X A C27 1 
HETATM 6696 C C31 . T7X L 6 .   ? 114.628 118.732 131.958 1.00 76.42  ? 510 T7X A C31 1 
HETATM 6697 C C32 . T7X L 6 .   ? 113.167 118.424 132.230 1.00 74.11  ? 510 T7X A C32 1 
HETATM 6698 C C33 . T7X L 6 .   ? 113.022 116.981 132.686 1.00 77.21  ? 510 T7X A C33 1 
HETATM 6699 C C34 . T7X L 6 .   ? 111.865 116.746 133.643 1.00 73.30  ? 510 T7X A C34 1 
HETATM 6700 C C35 . T7X L 6 .   ? 110.507 116.985 133.006 1.00 71.39  ? 510 T7X A C35 1 
HETATM 6701 C C36 . T7X L 6 .   ? 109.364 116.535 133.903 1.00 70.66  ? 510 T7X A C36 1 
HETATM 6702 C C37 . T7X L 6 .   ? 109.520 116.995 135.345 1.00 71.59  ? 510 T7X A C37 1 
HETATM 6703 C C38 . T7X L 6 .   ? 108.497 116.369 136.284 1.00 71.74  ? 510 T7X A C38 1 
HETATM 6704 C C28 . T7X L 6 .   ? 116.484 115.160 136.712 1.00 68.95  ? 510 T7X A C28 1 
HETATM 6705 C C1  . LBN M 3 .   ? 104.620 123.065 130.882 1.00 74.02  ? 511 LBN A C1  1 
HETATM 6706 N N1  . LBN M 3 .   ? 109.533 125.018 127.207 1.00 73.88  ? 511 LBN A N1  1 
HETATM 6707 P P1  . LBN M 3 .   ? 105.668 122.294 128.641 1.00 92.55  ? 511 LBN A P1  1 
HETATM 6708 C C2  . LBN M 3 .   ? 103.424 123.995 130.955 1.00 74.96  ? 511 LBN A C2  1 
HETATM 6709 C C3  . LBN M 3 .   ? 102.693 124.132 129.642 1.00 76.72  ? 511 LBN A C3  1 
HETATM 6710 C C4  . LBN M 3 .   ? 103.680 126.991 139.359 1.00 73.32  ? 511 LBN A C4  1 
HETATM 6711 C C6  . LBN M 3 .   ? 108.750 124.310 128.277 1.00 73.11  ? 511 LBN A C6  1 
HETATM 6712 O O1  . LBN M 3 .   ? 105.427 123.420 129.787 1.00 74.56  ? 511 LBN A O1  1 
HETATM 6713 C C7  . LBN M 3 .   ? 103.215 127.730 140.604 1.00 74.50  ? 511 LBN A C7  1 
HETATM 6714 C C9  . LBN M 3 .   ? 108.004 123.065 127.877 1.00 74.69  ? 511 LBN A C9  1 
HETATM 6715 O O2  . LBN M 3 .   ? 106.625 123.290 127.755 1.00 81.04  ? 511 LBN A O2  1 
HETATM 6716 C C10 . LBN M 3 .   ? 102.614 126.821 141.664 1.00 77.15  ? 511 LBN A C10 1 
HETATM 6717 C C12 . LBN M 3 .   ? 110.753 124.265 126.817 1.00 71.86  ? 511 LBN A C12 1 
HETATM 6718 O O3  . LBN M 3 .   ? 106.520 121.176 129.157 1.00 81.37  ? 511 LBN A O3  1 
HETATM 6719 C C13 . LBN M 3 .   ? 101.321 126.156 141.218 1.00 77.61  ? 511 LBN A C13 1 
HETATM 6720 C C15 . LBN M 3 .   ? 109.919 126.380 127.654 1.00 74.27  ? 511 LBN A C15 1 
HETATM 6721 O O4  . LBN M 3 .   ? 104.395 121.995 127.918 1.00 80.90  ? 511 LBN A O4  1 
HETATM 6722 C C16 . LBN M 3 .   ? 100.339 125.938 142.359 1.00 75.89  ? 511 LBN A C16 1 
HETATM 6723 C C18 . LBN M 3 .   ? 108.655 125.130 126.010 1.00 75.21  ? 511 LBN A C18 1 
HETATM 6724 C C19 . LBN M 3 .   ? 99.972  127.227 143.083 1.00 72.68  ? 511 LBN A C19 1 
HETATM 6725 C C21 . LBN M 3 .   ? 99.188  128.194 142.208 1.00 76.41  ? 511 LBN A C21 1 
HETATM 6726 C C25 . LBN M 3 .   ? 102.674 126.489 129.660 1.00 82.56  ? 511 LBN A C25 1 
HETATM 6727 O O5  . LBN M 3 .   ? 101.983 125.362 129.611 1.00 86.08  ? 511 LBN A O5  1 
HETATM 6728 C C26 . LBN M 3 .   ? 102.109 127.426 130.685 1.00 76.89  ? 511 LBN A C26 1 
HETATM 6729 O O6  . LBN M 3 .   ? 103.630 126.714 128.963 1.00 81.90  ? 511 LBN A O6  1 
HETATM 6730 C C27 . LBN M 3 .   ? 103.137 127.954 131.670 1.00 72.81  ? 511 LBN A C27 1 
HETATM 6731 C C28 . LBN M 3 .   ? 102.476 128.711 132.811 1.00 75.25  ? 511 LBN A C28 1 
HETATM 6732 C C29 . LBN M 3 .   ? 103.453 129.083 133.914 1.00 74.55  ? 511 LBN A C29 1 
HETATM 6733 C C30 . LBN M 3 .   ? 103.517 128.040 135.016 1.00 73.33  ? 511 LBN A C30 1 
HETATM 6734 C C31 . LBN M 3 .   ? 104.804 128.104 135.826 1.00 76.96  ? 511 LBN A C31 1 
HETATM 6735 C C32 . LBN M 3 .   ? 104.766 127.229 137.070 1.00 73.27  ? 511 LBN A C32 1 
HETATM 6736 C C33 . LBN M 3 .   ? 104.163 127.939 138.273 1.00 76.54  ? 511 LBN A C33 1 
HETATM 6737 C C34 . LBN M 3 .   ? 102.743 123.748 133.235 1.00 74.31  ? 511 LBN A C34 1 
HETATM 6738 O O7  . LBN M 3 .   ? 102.489 123.553 131.942 1.00 77.54  ? 511 LBN A O7  1 
HETATM 6739 C C35 . LBN M 3 .   ? 101.593 123.296 134.087 1.00 78.69  ? 511 LBN A C35 1 
HETATM 6740 O O8  . LBN M 3 .   ? 103.763 124.223 133.658 1.00 74.86  ? 511 LBN A O8  1 
HETATM 6741 C C36 . LBN M 3 .   ? 101.741 123.663 135.554 1.00 81.17  ? 511 LBN A C36 1 
HETATM 6742 C C37 . LBN M 3 .   ? 101.364 125.114 135.827 1.00 76.04  ? 511 LBN A C37 1 
HETATM 6743 C C1  . T7X N 6 .   ? 132.024 129.883 126.940 1.00 71.02  ? 501 T7X B C1  1 
HETATM 6744 O O1  . T7X N 6 .   ? 133.205 130.662 126.857 1.00 81.90  ? 501 T7X B O1  1 
HETATM 6745 P P1  . T7X N 6 .   ? 133.412 132.085 126.064 1.00 87.73  ? 501 T7X B P1  1 
HETATM 6746 C C2  . T7X N 6 .   ? 131.208 130.356 128.133 1.00 60.15  ? 501 T7X B C2  1 
HETATM 6747 O O2  . T7X N 6 .   ? 131.901 129.940 129.278 1.00 61.57  ? 501 T7X B O2  1 
HETATM 6748 C C3  . T7X N 6 .   ? 129.801 129.764 128.146 1.00 65.19  ? 501 T7X B C3  1 
HETATM 6749 O O3  . T7X N 6 .   ? 128.915 130.790 127.761 1.00 70.52  ? 501 T7X B O3  1 
HETATM 6750 C C4  . T7X N 6 .   ? 129.631 128.520 127.276 1.00 71.68  ? 501 T7X B C4  1 
HETATM 6751 O O4  . T7X N 6 .   ? 130.301 127.405 127.834 1.00 80.37  ? 501 T7X B O4  1 
HETATM 6752 C C5  . T7X N 6 .   ? 130.124 128.699 125.837 1.00 72.66  ? 501 T7X B C5  1 
HETATM 6753 O O5  . T7X N 6 .   ? 129.069 129.021 124.966 1.00 76.79  ? 501 T7X B O5  1 
HETATM 6754 C C6  . T7X N 6 .   ? 131.188 129.780 125.666 1.00 73.71  ? 501 T7X B C6  1 
HETATM 6755 O O6  . T7X N 6 .   ? 130.606 131.019 125.354 1.00 82.38  ? 501 T7X B O6  1 
HETATM 6756 C C7  . T7X N 6 .   ? 134.597 132.103 128.408 1.00 70.23  ? 501 T7X B C7  1 
HETATM 6757 C C8  . T7X N 6 .   ? 135.451 132.913 129.363 1.00 70.95  ? 501 T7X B C8  1 
HETATM 6758 C C9  . T7X N 6 .   ? 136.593 132.163 130.003 1.00 72.85  ? 501 T7X B C9  1 
HETATM 6759 C C10 . T7X N 6 .   ? 135.330 135.193 128.758 1.00 73.68  ? 501 T7X B C10 1 
HETATM 6760 C C11 . T7X N 6 .   ? 138.325 133.376 130.996 1.00 72.53  ? 501 T7X B C11 1 
HETATM 6761 O O11 . T7X N 6 .   ? 132.123 132.743 125.695 1.00 82.70  ? 501 T7X B O11 1 
HETATM 6762 C C12 . T7X N 6 .   ? 135.944 136.230 127.866 1.00 72.48  ? 501 T7X B C12 1 
HETATM 6763 O O12 . T7X N 6 .   ? 134.477 131.920 125.025 1.00 74.25  ? 501 T7X B O12 1 
HETATM 6764 C C13 . T7X N 6 .   ? 137.446 136.336 128.030 1.00 68.65  ? 501 T7X B C13 1 
HETATM 6765 O O13 . T7X N 6 .   ? 134.054 132.862 127.357 1.00 65.30  ? 501 T7X B O13 1 
HETATM 6766 C C14 . T7X N 6 .   ? 137.782 137.052 129.333 1.00 66.46  ? 501 T7X B C14 1 
HETATM 6767 C C15 . T7X N 6 .   ? 138.803 138.121 129.136 1.00 74.15  ? 501 T7X B C15 1 
HETATM 6768 C C16 . T7X N 6 .   ? 139.834 138.403 129.926 1.00 75.78  ? 501 T7X B C16 1 
HETATM 6769 O O16 . T7X N 6 .   ? 136.006 134.055 128.710 1.00 71.79  ? 501 T7X B O16 1 
HETATM 6770 C C17 . T7X N 6 .   ? 140.862 139.479 129.750 1.00 74.43  ? 501 T7X B C17 1 
HETATM 6771 O O17 . T7X N 6 .   ? 134.350 135.353 129.435 1.00 78.44  ? 501 T7X B O17 1 
HETATM 6772 C C18 . T7X N 6 .   ? 140.398 140.719 130.457 1.00 72.13  ? 501 T7X B C18 1 
HETATM 6773 O O18 . T7X N 6 .   ? 137.089 132.921 131.091 1.00 73.04  ? 501 T7X B O18 1 
HETATM 6774 C C19 . T7X N 6 .   ? 139.155 141.198 130.470 1.00 73.59  ? 501 T7X B C19 1 
HETATM 6775 O O19 . T7X N 6 .   ? 139.132 132.930 130.222 1.00 73.69  ? 501 T7X B O19 1 
HETATM 6776 C C20 . T7X N 6 .   ? 138.628 142.423 131.157 1.00 74.62  ? 501 T7X B C20 1 
HETATM 6777 C C21 . T7X N 6 .   ? 137.379 142.081 131.915 1.00 78.14  ? 501 T7X B C21 1 
HETATM 6778 C C22 . T7X N 6 .   ? 136.790 140.889 131.905 1.00 73.36  ? 501 T7X B C22 1 
HETATM 6779 C C23 . T7X N 6 .   ? 135.542 140.535 132.660 1.00 70.57  ? 501 T7X B C23 1 
HETATM 6780 C C24 . T7X N 6 .   ? 135.703 139.228 133.378 1.00 73.07  ? 501 T7X B C24 1 
HETATM 6781 C C25 . T7X N 6 .   ? 136.837 138.547 133.500 1.00 74.92  ? 501 T7X B C25 1 
HETATM 6782 C C26 . T7X N 6 .   ? 136.976 137.242 134.218 1.00 73.66  ? 501 T7X B C26 1 
HETATM 6783 C C27 . T7X N 6 .   ? 137.802 137.357 135.498 1.00 69.13  ? 501 T7X B C27 1 
HETATM 6784 C C31 . T7X N 6 .   ? 138.572 134.497 131.952 1.00 75.05  ? 501 T7X B C31 1 
HETATM 6785 C C32 . T7X N 6 .   ? 140.037 134.795 132.217 1.00 73.77  ? 501 T7X B C32 1 
HETATM 6786 C C33 . T7X N 6 .   ? 140.187 136.224 132.714 1.00 77.94  ? 501 T7X B C33 1 
HETATM 6787 C C34 . T7X N 6 .   ? 141.349 136.430 133.670 1.00 73.96  ? 501 T7X B C34 1 
HETATM 6788 C C35 . T7X N 6 .   ? 142.705 136.244 133.010 1.00 72.65  ? 501 T7X B C35 1 
HETATM 6789 C C36 . T7X N 6 .   ? 143.848 136.693 133.908 1.00 68.93  ? 501 T7X B C36 1 
HETATM 6790 C C37 . T7X N 6 .   ? 143.712 136.196 135.340 1.00 71.23  ? 501 T7X B C37 1 
HETATM 6791 C C38 . T7X N 6 .   ? 144.726 136.825 136.286 1.00 71.72  ? 501 T7X B C38 1 
HETATM 6792 C C28 . T7X N 6 .   ? 137.062 138.057 136.628 1.00 68.71  ? 501 T7X B C28 1 
HETATM 6793 O O2  . PSF O 2 .   ? 122.585 145.590 126.278 1.00 59.55  ? 502 PSF B O2  1 
HETATM 6794 O O1  . PSF O 2 .   ? 122.136 144.535 124.073 1.00 68.41  ? 502 PSF B O1  1 
HETATM 6795 P P   . PSF O 2 .   ? 123.397 144.983 124.999 1.00 79.13  ? 502 PSF B P   1 
HETATM 6796 O O4  . PSF O 2 .   ? 124.071 146.144 124.355 1.00 76.93  ? 502 PSF B O4  1 
HETATM 6797 O O3  . PSF O 2 .   ? 124.187 143.780 125.407 1.00 73.13  ? 502 PSF B O3  1 
HETATM 6798 C C2  . PSF O 2 .   ? 123.285 146.285 127.281 1.00 60.95  ? 502 PSF B C2  1 
HETATM 6799 C C3  . PSF O 2 .   ? 122.504 146.191 128.577 1.00 61.06  ? 502 PSF B C3  1 
HETATM 6800 O O11 . PSF O 2 .   ? 121.602 147.288 128.710 1.00 71.78  ? 502 PSF B O11 1 
HETATM 6801 O O12 . PSF O 2 .   ? 119.997 146.149 129.765 1.00 65.73  ? 502 PSF B O12 1 
HETATM 6802 C C1  . PSF O 2 .   ? 120.548 147.187 129.512 1.00 69.40  ? 502 PSF B C1  1 
HETATM 6803 C C4  . PSF O 2 .   ? 123.427 146.261 129.768 1.00 66.58  ? 502 PSF B C4  1 
HETATM 6804 C C5  . PSF O 2 .   ? 124.381 148.221 130.627 1.00 70.00  ? 502 PSF B C5  1 
HETATM 6805 O O51 . PSF O 2 .   ? 123.543 149.063 130.809 1.00 72.77  ? 502 PSF B O51 1 
HETATM 6806 O O52 . PSF O 2 .   ? 124.329 147.356 129.620 1.00 67.04  ? 502 PSF B O52 1 
HETATM 6807 C C6  . PSF O 2 .   ? 125.579 148.010 131.505 1.00 67.93  ? 502 PSF B C6  1 
HETATM 6808 C C7  . PSF O 2 .   ? 125.519 148.824 132.786 1.00 68.10  ? 502 PSF B C7  1 
HETATM 6809 C C13 . PSF O 2 .   ? 120.151 148.533 130.049 1.00 72.26  ? 502 PSF B C13 1 
HETATM 6810 C C14 . PSF O 2 .   ? 119.056 148.423 131.116 1.00 70.08  ? 502 PSF B C14 1 
HETATM 6811 C C15 . PSF O 2 .   ? 119.549 148.654 132.538 1.00 65.35  ? 502 PSF B C15 1 
HETATM 6812 N N   . PSF O 2 .   ? 120.287 143.322 122.670 1.00 64.29  ? 502 PSF B N   1 
HETATM 6813 C CA  . PSF O 2 .   ? 119.839 143.789 123.982 1.00 70.81  ? 502 PSF B CA  1 
HETATM 6814 C CB  . PSF O 2 .   ? 120.816 144.844 124.465 1.00 68.63  ? 502 PSF B CB  1 
HETATM 6815 C C   . PSF O 2 .   ? 118.401 144.341 123.965 1.00 74.53  ? 502 PSF B C   1 
HETATM 6816 O OT1 . PSF O 2 .   ? 117.607 143.724 123.226 1.00 72.25  ? 502 PSF B OT1 1 
HETATM 6817 O OT2 . PSF O 2 .   ? 118.142 145.334 124.670 1.00 71.04  ? 502 PSF B OT2 1 
HETATM 6818 C C8  . PSF O 2 .   ? 126.872 148.922 133.481 1.00 73.57  ? 502 PSF B C8  1 
HETATM 6819 C C9  . PSF O 2 .   ? 127.201 147.700 134.330 1.00 69.91  ? 502 PSF B C9  1 
HETATM 6820 C C10 . PSF O 2 .   ? 128.597 147.750 134.934 1.00 63.15  ? 502 PSF B C10 1 
HETATM 6821 C C16 . PSF O 2 .   ? 120.354 147.482 133.082 1.00 67.15  ? 502 PSF B C16 1 
HETATM 6822 C C17 . PSF O 2 .   ? 120.816 147.698 134.516 1.00 67.67  ? 502 PSF B C17 1 
HETATM 6823 O O2  . PSF P 2 .   ? 135.886 146.158 122.071 1.00 75.28  ? 503 PSF B O2  1 
HETATM 6824 O O1  . PSF P 2 .   ? 133.918 144.897 121.221 1.00 80.27  ? 503 PSF B O1  1 
HETATM 6825 P P   . PSF P 2 .   ? 135.128 145.841 120.662 1.00 90.52  ? 503 PSF B P   1 
HETATM 6826 O O4  . PSF P 2 .   ? 134.578 147.157 120.217 1.00 90.34  ? 503 PSF B O4  1 
HETATM 6827 O O3  . PSF P 2 .   ? 136.029 145.052 119.763 1.00 80.93  ? 503 PSF B O3  1 
HETATM 6828 C C2  . PSF P 2 .   ? 135.555 145.441 123.236 1.00 74.11  ? 503 PSF B C2  1 
HETATM 6829 C C3  . PSF P 2 .   ? 136.003 146.269 124.422 1.00 78.00  ? 503 PSF B C3  1 
HETATM 6830 O O11 . PSF P 2 .   ? 134.979 146.304 125.417 1.00 80.40  ? 503 PSF B O11 1 
HETATM 6831 O O12 . PSF P 2 .   ? 135.413 144.370 126.452 1.00 86.26  ? 503 PSF B O12 1 
HETATM 6832 C C1  . PSF P 2 .   ? 135.038 145.512 126.485 1.00 80.04  ? 503 PSF B C1  1 
HETATM 6833 C C4  . PSF P 2 .   ? 136.245 147.694 123.990 1.00 76.33  ? 503 PSF B C4  1 
HETATM 6834 C C5  . PSF P 2 .   ? 137.201 149.496 125.123 1.00 81.02  ? 503 PSF B C5  1 
HETATM 6835 O O51 . PSF P 2 .   ? 137.598 149.971 124.092 1.00 82.87  ? 503 PSF B O51 1 
HETATM 6836 O O52 . PSF P 2 .   ? 136.329 148.500 125.161 1.00 81.08  ? 503 PSF B O52 1 
HETATM 6837 C C6  . PSF P 2 .   ? 137.628 149.924 126.496 1.00 81.01  ? 503 PSF B C6  1 
HETATM 6838 C C7  . PSF P 2 .   ? 136.509 150.530 127.320 1.00 79.31  ? 503 PSF B C7  1 
HETATM 6839 C C13 . PSF P 2 .   ? 134.575 146.237 127.716 1.00 73.02  ? 503 PSF B C13 1 
HETATM 6840 C C14 . PSF P 2 .   ? 134.984 145.511 128.999 1.00 78.47  ? 503 PSF B C14 1 
HETATM 6841 C C15 . PSF P 2 .   ? 134.935 146.402 130.231 1.00 81.98  ? 503 PSF B C15 1 
HETATM 6842 N N   . PSF P 2 .   ? 132.417 144.604 118.998 1.00 80.29  ? 503 PSF B N   1 
HETATM 6843 C CA  . PSF P 2 .   ? 131.697 144.658 120.270 1.00 81.64  ? 503 PSF B CA  1 
HETATM 6844 C CB  . PSF P 2 .   ? 132.586 145.371 121.271 1.00 80.01  ? 503 PSF B CB  1 
HETATM 6845 C C   . PSF P 2 .   ? 130.322 145.347 120.153 1.00 84.32  ? 503 PSF B C   1 
HETATM 6846 O OT1 . PSF P 2 .   ? 129.345 144.674 120.545 1.00 86.93  ? 503 PSF B OT1 1 
HETATM 6847 O OT2 . PSF P 2 .   ? 130.282 146.500 119.686 1.00 82.65  ? 503 PSF B OT2 1 
HETATM 6848 C C8  . PSF P 2 .   ? 136.888 150.618 128.792 1.00 81.63  ? 503 PSF B C8  1 
HETATM 6849 C C9  . PSF P 2 .   ? 137.150 149.251 129.409 1.00 78.83  ? 503 PSF B C9  1 
HETATM 6850 C C10 . PSF P 2 .   ? 137.258 149.299 130.926 1.00 81.62  ? 503 PSF B C10 1 
HETATM 6851 C C16 . PSF P 2 .   ? 135.227 145.650 131.522 1.00 79.62  ? 503 PSF B C16 1 
HETATM 6852 C C17 . PSF P 2 .   ? 133.985 145.014 132.128 1.00 76.06  ? 503 PSF B C17 1 
HETATM 6853 C C1  . LBN Q 3 .   ? 123.193 130.290 164.041 1.00 79.63  ? 504 LBN B C1  1 
HETATM 6854 N N1  . LBN Q 3 .   ? 126.779 129.620 169.754 1.00 90.57  ? 504 LBN B N1  1 
HETATM 6855 P P1  . LBN Q 3 .   ? 124.650 130.645 166.183 1.00 109.43 ? 504 LBN B P1  1 
HETATM 6856 C C2  . LBN Q 3 .   ? 123.333 130.450 162.534 1.00 84.94  ? 504 LBN B C2  1 
HETATM 6857 C C3  . LBN Q 3 .   ? 124.663 129.968 162.000 1.00 84.58  ? 504 LBN B C3  1 
HETATM 6858 C C4  . LBN Q 3 .   ? 123.631 128.385 152.348 1.00 78.61  ? 504 LBN B C4  1 
HETATM 6859 C C5  . LBN Q 3 .   ? 125.048 124.459 152.024 1.00 77.79  ? 504 LBN B C5  1 
HETATM 6860 C C6  . LBN Q 3 .   ? 126.822 128.710 168.552 1.00 84.66  ? 504 LBN B C6  1 
HETATM 6861 O O1  . LBN Q 3 .   ? 124.471 130.186 164.628 1.00 86.54  ? 504 LBN B O1  1 
HETATM 6862 C C7  . LBN Q 3 .   ? 123.254 127.642 151.076 1.00 72.81  ? 504 LBN B C7  1 
HETATM 6863 C C8  . LBN Q 3 .   ? 125.234 123.319 151.070 1.00 78.27  ? 504 LBN B C8  1 
HETATM 6864 C C9  . LBN Q 3 .   ? 125.618 128.690 167.638 1.00 83.41  ? 504 LBN B C9  1 
HETATM 6865 O O2  . LBN Q 3 .   ? 125.790 129.494 166.493 1.00 92.38  ? 504 LBN B O2  1 
HETATM 6866 C C10 . LBN Q 3 .   ? 123.365 128.527 149.845 1.00 75.03  ? 504 LBN B C10 1 
HETATM 6867 C C11 . LBN Q 3 .   ? 126.701 123.013 150.773 1.00 81.13  ? 504 LBN B C11 1 
HETATM 6868 C C12 . LBN Q 3 .   ? 126.447 131.024 169.379 1.00 80.24  ? 504 LBN B C12 1 
HETATM 6869 O O3  . LBN Q 3 .   ? 125.291 131.998 166.286 1.00 87.20  ? 504 LBN B O3  1 
HETATM 6870 C C13 . LBN Q 3 .   ? 123.659 127.762 148.566 1.00 77.64  ? 504 LBN B C13 1 
HETATM 6871 C C14 . LBN Q 3 .   ? 126.913 121.682 150.064 1.00 77.82  ? 504 LBN B C14 1 
HETATM 6872 C C15 . LBN Q 3 .   ? 128.077 129.610 170.485 1.00 85.32  ? 504 LBN B C15 1 
HETATM 6873 O O4  . LBN Q 3 .   ? 123.399 130.364 166.954 1.00 84.68  ? 504 LBN B O4  1 
HETATM 6874 C C16 . LBN Q 3 .   ? 125.144 127.655 148.267 1.00 77.38  ? 504 LBN B C16 1 
HETATM 6875 C C17 . LBN Q 3 .   ? 128.383 121.370 149.810 1.00 76.67  ? 504 LBN B C17 1 
HETATM 6876 C C18 . LBN Q 3 .   ? 125.713 129.105 170.659 1.00 83.17  ? 504 LBN B C18 1 
HETATM 6877 C C19 . LBN Q 3 .   ? 125.440 127.382 146.797 1.00 79.37  ? 504 LBN B C19 1 
HETATM 6878 C C20 . LBN Q 3 .   ? 128.710 119.883 149.847 1.00 77.85  ? 504 LBN B C20 1 
HETATM 6879 C C21 . LBN Q 3 .   ? 126.237 126.108 146.564 1.00 82.37  ? 504 LBN B C21 1 
HETATM 6880 C C22 . LBN Q 3 .   ? 129.332 119.375 148.554 1.00 81.42  ? 504 LBN B C22 1 
HETATM 6881 C C23 . LBN Q 3 .   ? 129.765 117.915 148.609 1.00 79.46  ? 504 LBN B C23 1 
HETATM 6882 C C24 . LBN Q 3 .   ? 129.766 117.240 147.244 1.00 76.01  ? 504 LBN B C24 1 
HETATM 6883 C C25 . LBN Q 3 .   ? 126.254 130.545 160.379 1.00 82.77  ? 504 LBN B C25 1 
HETATM 6884 O O5  . LBN Q 3 .   ? 125.083 130.808 160.935 1.00 88.13  ? 504 LBN B O5  1 
HETATM 6885 C C26 . LBN Q 3 .   ? 126.460 131.340 159.123 1.00 79.62  ? 504 LBN B C26 1 
HETATM 6886 O O6  . LBN Q 3 .   ? 127.045 129.765 160.847 1.00 81.47  ? 504 LBN B O6  1 
HETATM 6887 C C27 . LBN Q 3 .   ? 125.544 130.982 157.964 1.00 74.24  ? 504 LBN B C27 1 
HETATM 6888 C C28 . LBN Q 3 .   ? 125.552 132.094 156.921 1.00 77.34  ? 504 LBN B C28 1 
HETATM 6889 C C29 . LBN Q 3 .   ? 124.620 131.865 155.739 1.00 81.43  ? 504 LBN B C29 1 
HETATM 6890 C C30 . LBN Q 3 .   ? 125.085 130.747 154.821 1.00 84.98  ? 504 LBN B C30 1 
HETATM 6891 C C31 . LBN Q 3 .   ? 124.192 129.515 154.864 1.00 83.91  ? 504 LBN B C31 1 
HETATM 6892 C C32 . LBN Q 3 .   ? 122.793 129.764 154.318 1.00 79.65  ? 504 LBN B C32 1 
HETATM 6893 C C33 . LBN Q 3 .   ? 122.429 128.876 153.136 1.00 79.89  ? 504 LBN B C33 1 
HETATM 6894 C C34 . LBN Q 3 .   ? 122.382 128.612 161.251 1.00 85.10  ? 504 LBN B C34 1 
HETATM 6895 O O7  . LBN Q 3 .   ? 122.257 129.812 161.825 1.00 89.51  ? 504 LBN B O7  1 
HETATM 6896 C C35 . LBN Q 3 .   ? 122.297 128.711 159.750 1.00 81.02  ? 504 LBN B C35 1 
HETATM 6897 O O8  . LBN Q 3 .   ? 122.526 127.589 161.870 1.00 81.48  ? 504 LBN B O8  1 
HETATM 6898 C C36 . LBN Q 3 .   ? 122.638 127.433 159.000 1.00 80.99  ? 504 LBN B C36 1 
HETATM 6899 C C37 . LBN Q 3 .   ? 124.113 127.055 159.082 1.00 76.21  ? 504 LBN B C37 1 
HETATM 6900 C C38 . LBN Q 3 .   ? 124.488 125.923 158.133 1.00 82.15  ? 504 LBN B C38 1 
HETATM 6901 C C39 . LBN Q 3 .   ? 124.490 126.328 156.662 1.00 81.33  ? 504 LBN B C39 1 
HETATM 6902 C C40 . LBN Q 3 .   ? 124.749 125.166 155.711 1.00 77.09  ? 504 LBN B C40 1 
HETATM 6903 C C41 . LBN Q 3 .   ? 125.075 125.612 154.284 1.00 76.55  ? 504 LBN B C41 1 
HETATM 6904 C C42 . LBN Q 3 .   ? 125.270 124.469 153.338 1.00 75.48  ? 504 LBN B C42 1 
HETATM 6905 C C1  . LBN R 3 .   ? 114.820 151.250 148.116 1.00 113.78 ? 505 LBN B C1  1 
HETATM 6906 N N1  . LBN R 3 .   ? 110.304 152.868 152.776 1.00 118.60 ? 505 LBN B N1  1 
HETATM 6907 P P1  . LBN R 3 .   ? 112.276 150.897 148.621 1.00 134.01 ? 505 LBN B P1  1 
HETATM 6908 C C2  . LBN R 3 .   ? 115.707 151.872 147.047 1.00 115.20 ? 505 LBN B C2  1 
HETATM 6909 C C3  . LBN R 3 .   ? 116.981 152.492 147.573 1.00 116.71 ? 505 LBN B C3  1 
HETATM 6910 C C6  . LBN R 3 .   ? 110.793 151.715 151.934 1.00 115.35 ? 505 LBN B C6  1 
HETATM 6911 O O1  . LBN R 3 .   ? 113.514 151.771 148.013 1.00 119.68 ? 505 LBN B O1  1 
HETATM 6912 C C9  . LBN R 3 .   ? 110.639 151.815 150.433 1.00 113.64 ? 505 LBN B C9  1 
HETATM 6913 O O2  . LBN R 3 .   ? 111.862 152.014 149.761 1.00 116.29 ? 505 LBN B O2  1 
HETATM 6914 C C12 . LBN R 3 .   ? 110.620 154.187 152.157 1.00 115.53 ? 505 LBN B C12 1 
HETATM 6915 O O3  . LBN R 3 .   ? 112.777 149.660 149.307 1.00 118.59 ? 505 LBN B O3  1 
HETATM 6916 C C15 . LBN R 3 .   ? 110.889 152.826 154.146 1.00 113.31 ? 505 LBN B C15 1 
HETATM 6917 O O4  . LBN R 3 .   ? 111.185 150.780 147.602 1.00 117.90 ? 505 LBN B O4  1 
HETATM 6918 C C18 . LBN R 3 .   ? 108.823 152.737 152.886 1.00 115.65 ? 505 LBN B C18 1 
HETATM 6919 C C25 . LBN R 3 .   ? 118.816 152.860 146.142 1.00 117.42 ? 505 LBN B C25 1 
HETATM 6920 O O5  . LBN R 3 .   ? 117.610 153.238 146.538 1.00 119.74 ? 505 LBN B O5  1 
HETATM 6921 C C26 . LBN R 3 .   ? 118.861 152.635 144.657 1.00 115.11 ? 505 LBN B C26 1 
HETATM 6922 O O6  . LBN R 3 .   ? 119.745 152.715 146.896 1.00 114.72 ? 505 LBN B O6  1 
HETATM 6923 C C27 . LBN R 3 .   ? 119.158 153.879 143.834 1.00 114.55 ? 505 LBN B C27 1 
HETATM 6924 C C28 . LBN R 3 .   ? 118.929 153.639 142.348 1.00 112.18 ? 505 LBN B C28 1 
HETATM 6925 C C29 . LBN R 3 .   ? 119.991 152.758 141.707 1.00 112.18 ? 505 LBN B C29 1 
HETATM 6926 C C30 . LBN R 3 .   ? 119.920 152.756 140.186 1.00 110.67 ? 505 LBN B C30 1 
HETATM 6927 C C34 . LBN R 3 .   ? 115.445 150.912 144.879 1.00 116.36 ? 505 LBN B C34 1 
HETATM 6928 O O7  . LBN R 3 .   ? 116.083 150.919 146.049 1.00 117.20 ? 505 LBN B O7  1 
HETATM 6929 C C35 . LBN R 3 .   ? 116.290 150.289 143.799 1.00 113.35 ? 505 LBN B C35 1 
HETATM 6930 O O8  . LBN R 3 .   ? 114.332 151.347 144.728 1.00 113.81 ? 505 LBN B O8  1 
HETATM 6931 C C36 . LBN R 3 .   ? 115.831 150.611 142.388 1.00 111.14 ? 505 LBN B C36 1 
HETATM 6932 C C37 . LBN R 3 .   ? 115.913 149.400 141.468 1.00 110.77 ? 505 LBN B C37 1 
HETATM 6933 C C38 . LBN R 3 .   ? 117.325 149.083 140.997 1.00 111.47 ? 505 LBN B C38 1 
HETATM 6934 C C39 . LBN R 3 .   ? 117.730 149.863 139.755 1.00 110.96 ? 505 LBN B C39 1 
HETATM 6935 C C40 . LBN R 3 .   ? 118.595 149.058 138.797 1.00 109.42 ? 505 LBN B C40 1 
HETATM 6936 C C41 . LBN R 3 .   ? 119.920 148.612 139.415 1.00 108.66 ? 505 LBN B C41 1 
HETATM 6937 C C1  . D12 S 4 .   ? 120.695 156.385 154.993 1.00 92.74  ? 506 D12 B C1  1 
HETATM 6938 C C2  . D12 S 4 .   ? 120.350 155.815 153.624 1.00 92.53  ? 506 D12 B C2  1 
HETATM 6939 C C3  . D12 S 4 .   ? 121.503 155.033 153.006 1.00 92.58  ? 506 D12 B C3  1 
HETATM 6940 C C4  . D12 S 4 .   ? 121.140 154.359 151.689 1.00 92.37  ? 506 D12 B C4  1 
HETATM 6941 C C5  . D12 S 4 .   ? 122.363 153.980 150.865 1.00 90.59  ? 506 D12 B C5  1 
HETATM 6942 C C6  . D12 S 4 .   ? 122.031 153.601 149.429 1.00 90.01  ? 506 D12 B C6  1 
HETATM 6943 C C7  . D12 S 4 .   ? 123.272 153.305 148.597 1.00 91.96  ? 506 D12 B C7  1 
HETATM 6944 C C8  . D12 S 4 .   ? 122.956 152.932 147.155 1.00 91.73  ? 506 D12 B C8  1 
HETATM 6945 C C9  . D12 S 4 .   ? 124.198 152.718 146.300 1.00 92.03  ? 506 D12 B C9  1 
HETATM 6946 C C10 . D12 S 4 .   ? 123.873 152.459 144.836 1.00 90.16  ? 506 D12 B C10 1 
HETATM 6947 C C11 . D12 S 4 .   ? 125.108 152.187 143.986 1.00 92.28  ? 506 D12 B C11 1 
HETATM 6948 C C12 . D12 S 4 .   ? 124.764 151.677 142.593 1.00 88.07  ? 506 D12 B C12 1 
HETATM 6949 C C01 . C14 T 5 .   ? 123.342 142.425 139.781 1.00 77.41  ? 507 C14 B C01 1 
HETATM 6950 C C02 . C14 T 5 .   ? 124.157 143.253 140.762 1.00 79.90  ? 507 C14 B C02 1 
HETATM 6951 C C03 . C14 T 5 .   ? 124.151 142.672 142.169 1.00 78.12  ? 507 C14 B C03 1 
HETATM 6952 C C04 . C14 T 5 .   ? 124.652 143.658 143.216 1.00 76.99  ? 507 C14 B C04 1 
HETATM 6953 C C05 . C14 T 5 .   ? 124.489 143.179 144.652 1.00 77.96  ? 507 C14 B C05 1 
HETATM 6954 C C06 . C14 T 5 .   ? 124.489 144.338 145.641 1.00 79.82  ? 507 C14 B C06 1 
HETATM 6955 C C07 . C14 T 5 .   ? 124.663 143.930 147.098 1.00 81.29  ? 507 C14 B C07 1 
HETATM 6956 C C08 . C14 T 5 .   ? 125.544 144.915 147.854 1.00 81.82  ? 507 C14 B C08 1 
HETATM 6957 C C09 . C14 T 5 .   ? 125.611 144.679 149.355 1.00 77.89  ? 507 C14 B C09 1 
HETATM 6958 C C10 . C14 T 5 .   ? 126.505 145.701 150.048 1.00 80.15  ? 507 C14 B C10 1 
HETATM 6959 C C11 . C14 T 5 .   ? 126.483 145.616 151.568 1.00 81.44  ? 507 C14 B C11 1 
HETATM 6960 C C12 . C14 T 5 .   ? 127.339 146.686 152.233 1.00 80.42  ? 507 C14 B C12 1 
HETATM 6961 C C13 . C14 T 5 .   ? 127.281 146.645 153.755 1.00 82.01  ? 507 C14 B C13 1 
HETATM 6962 C C14 . C14 T 5 .   ? 128.168 147.696 154.410 1.00 80.87  ? 507 C14 B C14 1 
HETATM 6963 C C1  . LBN U 3 .   ? 102.862 131.524 125.531 1.00 70.11  ? 508 LBN B C1  1 
HETATM 6964 N N1  . LBN U 3 .   ? 106.927 129.668 121.545 1.00 80.96  ? 508 LBN B N1  1 
HETATM 6965 P P1  . LBN U 3 .   ? 103.380 129.475 124.009 1.00 94.44  ? 508 LBN B P1  1 
HETATM 6966 C C2  . LBN U 3 .   ? 103.210 131.114 126.955 1.00 64.52  ? 508 LBN B C2  1 
HETATM 6967 C C3  . LBN U 3 .   ? 103.508 132.274 127.871 1.00 69.46  ? 508 LBN B C3  1 
HETATM 6968 C C4  . LBN U 3 .   ? 109.308 135.756 134.794 1.00 64.10  ? 508 LBN B C4  1 
HETATM 6969 C C5  . LBN U 3 .   ? 95.908  133.877 137.479 1.00 73.15  ? 508 LBN B C5  1 
HETATM 6970 C C6  . LBN U 3 .   ? 106.106 130.892 121.845 1.00 74.21  ? 508 LBN B C6  1 
HETATM 6971 O O1  . LBN U 3 .   ? 102.337 130.438 124.806 1.00 73.70  ? 508 LBN B O1  1 
HETATM 6972 C C7  . LBN U 3 .   ? 108.471 137.001 134.554 1.00 66.51  ? 508 LBN B C7  1 
HETATM 6973 C C8  . LBN U 3 .   ? 95.939  134.807 138.652 1.00 72.09  ? 508 LBN B C8  1 
HETATM 6974 C C9  . LBN U 3 .   ? 104.623 130.709 122.070 1.00 71.92  ? 508 LBN B C9  1 
HETATM 6975 O O2  . LBN U 3 .   ? 104.267 130.735 123.431 1.00 78.12  ? 508 LBN B O2  1 
HETATM 6976 C C10 . LBN U 3 .   ? 109.282 138.285 134.587 1.00 67.81  ? 508 LBN B C10 1 
HETATM 6977 C C11 . LBN U 3 .   ? 96.011  134.057 139.985 1.00 72.79  ? 508 LBN B C11 1 
HETATM 6978 C C12 . LBN U 3 .   ? 106.746 128.621 122.587 1.00 71.75  ? 508 LBN B C12 1 
HETATM 6979 O O3  . LBN U 3 .   ? 104.230 128.692 124.964 1.00 80.02  ? 508 LBN B O3  1 
HETATM 6980 C C13 . LBN U 3 .   ? 108.665 139.345 135.488 1.00 70.78  ? 508 LBN B C13 1 
HETATM 6981 C C14 . LBN U 3 .   ? 95.856  134.970 141.197 1.00 75.43  ? 508 LBN B C14 1 
HETATM 6982 C C15 . LBN U 3 .   ? 108.377 129.988 121.411 1.00 79.13  ? 508 LBN B C15 1 
HETATM 6983 O O4  . LBN U 3 .   ? 102.686 128.771 122.888 1.00 78.01  ? 508 LBN B O4  1 
HETATM 6984 C C16 . LBN U 3 .   ? 109.505 140.607 135.595 1.00 69.04  ? 508 LBN B C16 1 
HETATM 6985 C C17 . LBN U 3 .   ? 96.000  134.238 142.526 1.00 72.59  ? 508 LBN B C17 1 
HETATM 6986 C C18 . LBN U 3 .   ? 106.432 129.124 120.251 1.00 76.40  ? 508 LBN B C18 1 
HETATM 6987 C C19 . LBN U 3 .   ? 108.796 141.727 136.339 1.00 66.43  ? 508 LBN B C19 1 
HETATM 6988 C C20 . LBN U 3 .   ? 95.461  135.021 143.718 1.00 73.19  ? 508 LBN B C20 1 
HETATM 6989 C C21 . LBN U 3 .   ? 109.511 143.062 136.212 1.00 67.91  ? 508 LBN B C21 1 
HETATM 6990 C C22 . LBN U 3 .   ? 95.201  134.153 144.943 1.00 77.18  ? 508 LBN B C22 1 
HETATM 6991 C C23 . LBN U 3 .   ? 96.469  133.810 145.715 1.00 77.64  ? 508 LBN B C23 1 
HETATM 6992 C C24 . LBN U 3 .   ? 96.378  132.487 146.462 1.00 74.33  ? 508 LBN B C24 1 
HETATM 6993 C C25 . LBN U 3 .   ? 104.781 131.046 129.425 1.00 78.43  ? 508 LBN B C25 1 
HETATM 6994 O O5  . LBN U 3 .   ? 103.712 131.786 129.187 1.00 83.11  ? 508 LBN B O5  1 
HETATM 6995 C C26 . LBN U 3 .   ? 106.026 131.875 129.457 1.00 69.93  ? 508 LBN B C26 1 
HETATM 6996 O O6  . LBN U 3 .   ? 104.737 129.854 129.598 1.00 80.83  ? 508 LBN B O6  1 
HETATM 6997 C C27 . LBN U 3 .   ? 107.141 131.283 130.302 1.00 68.64  ? 508 LBN B C27 1 
HETATM 6998 C C28 . LBN U 3 .   ? 106.737 131.160 131.763 1.00 72.95  ? 508 LBN B C28 1 
HETATM 6999 C C29 . LBN U 3 .   ? 107.705 130.314 132.577 1.00 73.17  ? 508 LBN B C29 1 
HETATM 7000 C C30 . LBN U 3 .   ? 108.823 131.125 133.209 1.00 68.57  ? 508 LBN B C30 1 
HETATM 7001 C C31 . LBN U 3 .   ? 108.330 132.032 134.325 1.00 71.32  ? 508 LBN B C31 1 
HETATM 7002 C C32 . LBN U 3 .   ? 109.235 133.232 134.551 1.00 72.62  ? 508 LBN B C32 1 
HETATM 7003 C C33 . LBN U 3 .   ? 108.464 134.498 134.899 1.00 70.40  ? 508 LBN B C33 1 
HETATM 7004 C C34 . LBN U 3 .   ? 101.043 130.839 127.989 1.00 77.63  ? 508 LBN B C34 1 
HETATM 7005 O O7  . LBN U 3 .   ? 102.195 130.313 127.575 1.00 76.85  ? 508 LBN B O7  1 
HETATM 7006 C C35 . LBN U 3 .   ? 100.758 130.504 129.427 1.00 71.95  ? 508 LBN B C35 1 
HETATM 7007 O O8  . LBN U 3 .   ? 100.314 131.491 127.290 1.00 81.19  ? 508 LBN B O8  1 
HETATM 7008 C C36 . LBN U 3 .   ? 99.467  131.113 129.946 1.00 70.81  ? 508 LBN B C36 1 
HETATM 7009 C C37 . LBN U 3 .   ? 99.259  130.857 131.434 1.00 72.75  ? 508 LBN B C37 1 
HETATM 7010 C C38 . LBN U 3 .   ? 98.625  132.041 132.153 1.00 70.48  ? 508 LBN B C38 1 
HETATM 7011 C C39 . LBN U 3 .   ? 98.113  131.691 133.543 1.00 70.34  ? 508 LBN B C39 1 
HETATM 7012 C C40 . LBN U 3 .   ? 97.752  132.900 134.397 1.00 69.60  ? 508 LBN B C40 1 
HETATM 7013 C C41 . LBN U 3 .   ? 96.860  132.507 135.575 1.00 74.62  ? 508 LBN B C41 1 
HETATM 7014 C C42 . LBN U 3 .   ? 96.931  133.446 136.739 1.00 74.68  ? 508 LBN B C42 1 
HETATM 7015 C C1  . LBN V 3 .   ? 128.035 144.537 157.572 1.00 80.59  ? 509 LBN B C1  1 
HETATM 7016 N N1  . LBN V 3 .   ? 129.712 139.356 160.409 1.00 83.41  ? 509 LBN B N1  1 
HETATM 7017 P P1  . LBN V 3 .   ? 130.173 143.338 158.470 1.00 108.13 ? 509 LBN B P1  1 
HETATM 7018 C C2  . LBN V 3 .   ? 127.387 143.914 156.344 1.00 88.62  ? 509 LBN B C2  1 
HETATM 7019 C C3  . LBN V 3 .   ? 128.357 143.272 155.379 1.00 87.64  ? 509 LBN B C3  1 
HETATM 7020 C C4  . LBN V 3 .   ? 126.072 139.145 149.148 1.00 85.86  ? 509 LBN B C4  1 
HETATM 7021 C C5  . LBN V 3 .   ? 119.833 139.309 150.859 1.00 83.79  ? 509 LBN B C5  1 
HETATM 7022 C C6  . LBN V 3 .   ? 129.765 140.734 161.011 1.00 83.95  ? 509 LBN B C6  1 
HETATM 7023 O O1  . LBN V 3 .   ? 128.555 143.531 158.410 1.00 86.47  ? 509 LBN B O1  1 
HETATM 7024 C C7  . LBN V 3 .   ? 126.660 139.031 147.747 1.00 81.19  ? 509 LBN B C7  1 
HETATM 7025 C C8  . LBN V 3 .   ? 118.881 138.167 151.004 1.00 82.06  ? 509 LBN B C8  1 
HETATM 7026 C C9  . LBN V 3 .   ? 130.756 141.722 160.438 1.00 87.38  ? 509 LBN B C9  1 
HETATM 7027 O O2  . LBN V 3 .   ? 130.155 142.940 160.068 1.00 95.16  ? 509 LBN B O2  1 
HETATM 7028 C C10 . LBN V 3 .   ? 125.603 138.809 146.677 1.00 83.21  ? 509 LBN B C10 1 
HETATM 7029 C C11 . LBN V 3 .   ? 117.469 138.665 151.322 1.00 82.29  ? 509 LBN B C11 1 
HETATM 7030 C C12 . LBN V 3 .   ? 128.719 139.261 159.305 1.00 76.08  ? 509 LBN B C12 1 
HETATM 7031 O O3  . LBN V 3 .   ? 130.605 142.142 157.675 1.00 86.41  ? 509 LBN B O3  1 
HETATM 7032 C C13 . LBN V 3 .   ? 124.958 137.429 146.758 1.00 82.86  ? 509 LBN B C13 1 
HETATM 7033 C C14 . LBN V 3 .   ? 116.565 137.593 151.910 1.00 77.67  ? 509 LBN B C14 1 
HETATM 7034 C C15 . LBN V 3 .   ? 131.046 138.946 159.904 1.00 88.32  ? 509 LBN B C15 1 
HETATM 7035 O O4  . LBN V 3 .   ? 130.869 144.646 158.265 1.00 89.53  ? 509 LBN B O4  1 
HETATM 7036 C C16 . LBN V 3 .   ? 123.522 137.387 146.255 1.00 78.51  ? 509 LBN B C16 1 
HETATM 7037 C C17 . LBN V 3 .   ? 115.825 138.055 153.156 1.00 77.24  ? 509 LBN B C17 1 
HETATM 7038 C C18 . LBN V 3 .   ? 129.311 138.421 161.493 1.00 80.60  ? 509 LBN B C18 1 
HETATM 7039 C C19 . LBN V 3 .   ? 122.806 138.719 146.426 1.00 85.36  ? 509 LBN B C19 1 
HETATM 7040 C C20 . LBN V 3 .   ? 116.152 137.212 154.381 1.00 86.84  ? 509 LBN B C20 1 
HETATM 7041 C C21 . LBN V 3 .   ? 121.323 138.565 146.714 1.00 83.84  ? 509 LBN B C21 1 
HETATM 7042 C C22 . LBN V 3 .   ? 117.596 137.359 154.845 1.00 88.15  ? 509 LBN B C22 1 
HETATM 7043 C C23 . LBN V 3 .   ? 118.060 136.251 155.781 1.00 83.46  ? 509 LBN B C23 1 
HETATM 7044 C C24 . LBN V 3 .   ? 117.105 136.033 156.943 1.00 80.08  ? 509 LBN B C24 1 
HETATM 7045 C C25 . LBN V 3 .   ? 130.265 143.851 154.120 1.00 89.78  ? 509 LBN B C25 1 
HETATM 7046 O O5  . LBN V 3 .   ? 129.255 144.254 154.877 1.00 91.30  ? 509 LBN B O5  1 
HETATM 7047 C C26 . LBN V 3 .   ? 129.784 143.146 152.887 1.00 86.98  ? 509 LBN B C26 1 
HETATM 7048 O O6  . LBN V 3 .   ? 131.422 144.041 154.402 1.00 86.66  ? 509 LBN B O6  1 
HETATM 7049 C C27 . LBN V 3 .   ? 130.785 142.160 152.305 1.00 83.71  ? 509 LBN B C27 1 
HETATM 7050 C C28 . LBN V 3 .   ? 130.391 141.727 150.900 1.00 80.42  ? 509 LBN B C28 1 
HETATM 7051 C C29 . LBN V 3 .   ? 128.927 141.329 150.780 1.00 81.16  ? 509 LBN B C29 1 
HETATM 7052 C C30 . LBN V 3 .   ? 128.600 140.035 151.510 1.00 85.53  ? 509 LBN B C30 1 
HETATM 7053 C C31 . LBN V 3 .   ? 127.108 139.860 151.769 1.00 88.43  ? 509 LBN B C31 1 
HETATM 7054 C C32 . LBN V 3 .   ? 126.605 138.439 151.556 1.00 84.12  ? 509 LBN B C32 1 
HETATM 7055 C C33 . LBN V 3 .   ? 126.544 138.041 150.087 1.00 87.66  ? 509 LBN B C33 1 
HETATM 7056 C C34 . LBN V 3 .   ? 125.203 142.970 156.205 1.00 88.87  ? 509 LBN B C34 1 
HETATM 7057 O O7  . LBN V 3 .   ? 126.432 142.914 156.709 1.00 92.29  ? 509 LBN B O7  1 
HETATM 7058 C C35 . LBN V 3 .   ? 124.895 141.758 155.373 1.00 86.39  ? 509 LBN B C35 1 
HETATM 7059 O O8  . LBN V 3 .   ? 124.448 143.884 156.407 1.00 85.60  ? 509 LBN B O8  1 
HETATM 7060 C C36 . LBN V 3 .   ? 125.108 141.969 153.885 1.00 79.99  ? 509 LBN B C36 1 
HETATM 7061 C C37 . LBN V 3 .   ? 123.796 142.224 153.155 1.00 80.85  ? 509 LBN B C37 1 
HETATM 7062 C C38 . LBN V 3 .   ? 123.435 141.118 152.175 1.00 80.44  ? 509 LBN B C38 1 
HETATM 7063 C C39 . LBN V 3 .   ? 123.435 141.577 150.723 1.00 84.56  ? 509 LBN B C39 1 
HETATM 7064 C C40 . LBN V 3 .   ? 122.678 140.627 149.806 1.00 86.04  ? 509 LBN B C40 1 
HETATM 7065 C C41 . LBN V 3 .   ? 121.216 141.033 149.631 1.00 87.60  ? 509 LBN B C41 1 
HETATM 7066 C C42 . LBN V 3 .   ? 120.270 139.879 149.738 1.00 83.89  ? 509 LBN B C42 1 
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